pax_global_header00006660000000000000000000000064146706015740014524gustar00rootroot0000000000000052 comment=bcf6c624342d0819e418169e7e5cd1277aefe7f8 bcftools-1.21/000077500000000000000000000000001467060157400132625ustar00rootroot00000000000000bcftools-1.21/AUTHORS000066400000000000000000000006531467060157400143360ustar00rootroot00000000000000BCFtools package is currently maintained by Petr Danecek, Shane McCarthy and John Marshall. Alphabetical list of people who have made contributions: Nicholas Clarke Travis Collier Petr Danecek Javier Herrero Warren Kretzschmar Heng Li Shane McCarthy John Marshall Joel Martin Stephan Schiffels bcftools-1.21/HMM.c000066400000000000000000000435111467060157400140530ustar00rootroot00000000000000/* The MIT License Copyright (c) 2014-2017 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include "HMM.h" typedef struct { int nstates; // number of hmm's states uint32_t snap_at_pos; // snapshot at this position, 0 when inactive double *vit_prob; // viterbi probabilities, NULL for uniform probs double *fwd_prob; // transition probabilities double *bwd_prob; // transition probabilities } snapshot_t; struct _hmm_t { int nstates; // number of states double *vprob, *vprob_tmp; // viterbi probs [nstates] uint8_t *vpath; // viterbi path [nstates*nvpath] double *bwd, *bwd_tmp; // bwd probs [nstates] double *fwd; // fwd probs [nstates*(nfwd+1)] int nvpath, nfwd; int ntprob_arr; // number of pre-calculated tprob matrices double *curr_tprob, *tmp; // Temporary arrays; curr_tprob is short lived, valid only for // one site (that is, one step of Viterbi algorithm) double *tprob_arr; // Array of transition matrices, precalculated to ntprob_arr // positions. The first matrix is the initial tprob matrix // set by hmm_init() or hmm_set_tprob() set_tprob_f set_tprob; // Optional user function to set / modify transition probabilities // at each site (one step of Viterbi algorithm) void *set_tprob_data; snapshot_t init, state; // Initial and current state probs. Set state from snapshot if prev_snap_pos!=0 or from init otherwise snapshot_t *snapshot; // snapshot->snap_at_pos .. request a snapshot at this position // hmm->state.snap_at_pos .. the current state comes from snapshot made at this position }; uint8_t *hmm_get_viterbi_path(hmm_t *hmm) { return hmm->vpath; } double *hmm_get_tprob(hmm_t *hmm) { return hmm->tprob_arr; } int hmm_get_nstates(hmm_t *hmm) { return hmm->nstates; } double *hmm_get_fwd_bwd_prob(hmm_t *hmm) { return hmm->fwd; } static inline void multiply_matrix(int n, double *a, double *b, double *dst, double *tmp) { double *out = dst; if ( a==dst || b==dst ) out = tmp; int i,j,k; for (i=0; iinit.snap_at_pos = hmm->state.snap_at_pos = 0; if ( !hmm->init.vit_prob ) hmm->init.vit_prob = (double*) malloc(sizeof(double)*hmm->nstates); if ( !hmm->init.fwd_prob ) hmm->init.fwd_prob = (double*) malloc(sizeof(double)*hmm->nstates); if ( !hmm->init.bwd_prob ) hmm->init.bwd_prob = (double*) malloc(sizeof(double)*hmm->nstates); if ( !hmm->state.vit_prob ) hmm->state.vit_prob = (double*) malloc(sizeof(double)*hmm->nstates); if ( !hmm->state.fwd_prob ) hmm->state.fwd_prob = (double*) malloc(sizeof(double)*hmm->nstates); if ( !hmm->state.bwd_prob ) hmm->state.bwd_prob = (double*) malloc(sizeof(double)*hmm->nstates); int i; if ( probs ) { memcpy(hmm->init.vit_prob,probs,sizeof(double)*hmm->nstates); double sum = 0; for (i=0; instates; i++) sum += hmm->init.vit_prob[i]; for (i=0; instates; i++) hmm->init.vit_prob[i] /= sum; } else for (i=0; instates; i++) hmm->init.vit_prob[i] = 1./hmm->nstates; memcpy(hmm->init.fwd_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); // these remain unchanged memcpy(hmm->init.bwd_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); memcpy(hmm->state.vit_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); // can be changed by snapshotting memcpy(hmm->state.fwd_prob,hmm->init.fwd_prob,sizeof(double)*hmm->nstates); memcpy(hmm->state.bwd_prob,hmm->init.bwd_prob,sizeof(double)*hmm->nstates); } hmm_t *hmm_init(int nstates, double *tprob, int ntprob) { hmm_t *hmm = (hmm_t*) calloc(1,sizeof(hmm_t)); hmm->nstates = nstates; hmm->curr_tprob = (double*) malloc(sizeof(double)*nstates*nstates); hmm->tmp = (double*) malloc(sizeof(double)*nstates*nstates); hmm_set_tprob(hmm, tprob, ntprob); hmm_init_states(hmm, NULL); return hmm; } void *hmm_snapshot(hmm_t *hmm, void *_snapshot, uint32_t pos) { snapshot_t *snapshot = (snapshot_t*) _snapshot; if ( snapshot && snapshot->nstates!=hmm->nstates ) { free(snapshot); snapshot = NULL; } if ( !snapshot ) { // Allocate the snapshot as a single memory block so that it can be // free()-ed by the user. So make sure the arrays are aligned.. size_t str_size = sizeof(snapshot_t); size_t dbl_size = sizeof(double); size_t pad_size = (dbl_size - str_size % dbl_size) % dbl_size; uint8_t *mem = (uint8_t*) malloc(str_size + pad_size + dbl_size*2*hmm->nstates); snapshot = (snapshot_t*) mem; snapshot->nstates = hmm->nstates; snapshot->vit_prob = (double*) (mem + str_size + pad_size); snapshot->fwd_prob = snapshot->vit_prob + hmm->nstates; } snapshot->snap_at_pos = pos; hmm->snapshot = snapshot; return snapshot; } void hmm_restore(hmm_t *hmm, void *_snapshot) { snapshot_t *snapshot = (snapshot_t*) _snapshot; if ( !snapshot || !snapshot->snap_at_pos ) { hmm->state.snap_at_pos = 0; memcpy(hmm->state.vit_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); memcpy(hmm->state.fwd_prob,hmm->init.fwd_prob,sizeof(double)*hmm->nstates); } else { hmm->state.snap_at_pos = snapshot->snap_at_pos; memcpy(hmm->state.vit_prob,snapshot->vit_prob,sizeof(double)*hmm->nstates); memcpy(hmm->state.fwd_prob,snapshot->fwd_prob,sizeof(double)*hmm->nstates); } } void hmm_reset(hmm_t *hmm, void *_snapshot) { snapshot_t *snapshot = (snapshot_t*) _snapshot; if ( snapshot ) snapshot->snap_at_pos = 0; hmm->state.snap_at_pos = 0; memcpy(hmm->state.vit_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); memcpy(hmm->state.fwd_prob,hmm->init.fwd_prob,sizeof(double)*hmm->nstates); } void hmm_set_tprob(hmm_t *hmm, double *tprob, int ntprob) { hmm->ntprob_arr = ntprob; if ( ntprob<=0 ) ntprob = 1; if ( !hmm->tprob_arr ) hmm->tprob_arr = (double*) malloc(sizeof(double)*hmm->nstates*hmm->nstates*ntprob); memcpy(hmm->tprob_arr,tprob,sizeof(double)*hmm->nstates*hmm->nstates); int i; for (i=1; instates, hmm->tprob_arr, hmm->tprob_arr+(i-1)*hmm->nstates*hmm->nstates, hmm->tprob_arr+i*hmm->nstates*hmm->nstates, hmm->tmp); } void hmm_set_tprob_func(hmm_t *hmm, set_tprob_f set_tprob, void *data) { hmm->set_tprob = set_tprob; hmm->set_tprob_data = data; } static void _set_tprob(hmm_t *hmm, int pos_diff) { assert( pos_diff>=0 ); int i, n; n = hmm->ntprob_arr ? pos_diff % hmm->ntprob_arr : 0; // n-th precalculated matrix memcpy(hmm->curr_tprob, hmm->tprob_arr+n*hmm->nstates*hmm->nstates, sizeof(*hmm->curr_tprob)*hmm->nstates*hmm->nstates); if ( hmm->ntprob_arr > 0 ) { n = pos_diff / hmm->ntprob_arr; // number of full blocks to jump for (i=0; instates, hmm->tprob_arr+(hmm->ntprob_arr-1)*hmm->nstates*hmm->nstates, hmm->curr_tprob, hmm->curr_tprob, hmm->tmp); } } void hmm_run_viterbi(hmm_t *hmm, int n, double *eprobs, uint32_t *sites) { // Init arrays when run for the first time if ( hmm->nvpath < n ) { hmm->nvpath = n; hmm->vpath = (uint8_t*) realloc(hmm->vpath, sizeof(uint8_t)*hmm->nvpath*hmm->nstates); } if ( !hmm->vprob ) { hmm->vprob = (double*) malloc(sizeof(double)*hmm->nstates); hmm->vprob_tmp = (double*) malloc(sizeof(double)*hmm->nstates); } // Init all states with equal likelihood int i,j, nstates = hmm->nstates; memcpy(hmm->vprob, hmm->state.vit_prob, sizeof(*hmm->state.vit_prob)*nstates); uint32_t prev_pos = hmm->state.snap_at_pos ? hmm->state.snap_at_pos : sites[0]; // Run Viterbi for (i=0; ivpath[i*nstates]; double *eprob = &eprobs[i*nstates]; int pos_diff = sites[i] == prev_pos ? 0 : sites[i] - prev_pos - 1; _set_tprob(hmm, pos_diff); if ( hmm->set_tprob ) hmm->set_tprob(hmm, prev_pos, sites[i], hmm->set_tprob_data, hmm->curr_tprob); prev_pos = sites[i]; double vnorm = 0; for (j=0; jvprob[k] * MAT(hmm->curr_tprob,hmm->nstates,j,k); if ( vmax < pval ) { vmax = pval; k_vmax = k; } } vpath[j] = k_vmax; hmm->vprob_tmp[j] = vmax * eprob[j]; vnorm += hmm->vprob_tmp[j]; } for (j=0; jvprob_tmp[j] /= vnorm; double *tmp = hmm->vprob; hmm->vprob = hmm->vprob_tmp; hmm->vprob_tmp = tmp; if ( hmm->snapshot && sites[i]==hmm->snapshot->snap_at_pos ) memcpy(hmm->snapshot->vit_prob, hmm->vprob, sizeof(*hmm->vprob)*nstates); } // Find the most likely state int iptr = 0; for (i=1; ivprob[iptr] < hmm->vprob[i] ) iptr = i; // Trace back the Viterbi path, we are reusing vpath for storing the states (vpath[i*nstates]) for (i=n-1; i>=0; i--) { assert( iptrvpath[i*nstates + iptr]vpath[i*nstates + iptr]; hmm->vpath[i*nstates] = iptr; // reusing the array for different purpose here } } void hmm_run_fwd_bwd(hmm_t *hmm, int n, double *eprobs, uint32_t *sites) { // Init arrays when run for the first time if ( hmm->nfwd < n ) { hmm->nfwd = n; hmm->fwd = (double*) realloc(hmm->fwd, sizeof(double)*(hmm->nfwd+1)*hmm->nstates); } if ( !hmm->bwd ) { hmm->bwd = (double*) malloc(sizeof(double)*hmm->nstates); hmm->bwd_tmp = (double*) malloc(sizeof(double)*hmm->nstates); } int i,j,k, nstates = hmm->nstates; memcpy(hmm->fwd, hmm->state.fwd_prob, sizeof(*hmm->state.fwd_prob)*nstates); memcpy(hmm->bwd, hmm->state.bwd_prob, sizeof(*hmm->state.bwd_prob)*nstates); uint32_t prev_pos = hmm->state.snap_at_pos ? hmm->state.snap_at_pos : sites[0]; // Run fwd for (i=0; ifwd[i*nstates]; double *fwd = &hmm->fwd[(i+1)*nstates]; double *eprob = &eprobs[i*nstates]; int pos_diff = sites[i] == prev_pos ? 0 : sites[i] - prev_pos - 1; _set_tprob(hmm, pos_diff); if ( hmm->set_tprob ) hmm->set_tprob(hmm, prev_pos, sites[i], hmm->set_tprob_data, hmm->curr_tprob); prev_pos = sites[i]; double norm = 0; for (j=0; jcurr_tprob,hmm->nstates,j,k); fwd[j] = pval * eprob[j]; norm += fwd[j]; } for (j=0; jsnapshot && sites[i]==hmm->snapshot->snap_at_pos ) memcpy(hmm->snapshot->fwd_prob, fwd, sizeof(*fwd)*nstates); } // Run bwd double *bwd = hmm->bwd, *bwd_tmp = hmm->bwd_tmp; prev_pos = sites[n-1]; for (i=0; ifwd[(n-i)*nstates]; double *eprob = &eprobs[(n-i-1)*nstates]; int pos_diff = sites[n-i-1] == prev_pos ? 0 : prev_pos - sites[n-i-1] - 1; _set_tprob(hmm, pos_diff); if ( hmm->set_tprob ) hmm->set_tprob(hmm, sites[n-i-1], prev_pos, hmm->set_tprob_data, hmm->curr_tprob); prev_pos = sites[n-i-1]; double bwd_norm = 0; for (j=0; jcurr_tprob,hmm->nstates,k,j); bwd_tmp[j] = pval; bwd_norm += pval; } double norm = 0; for (j=0; jnfwd < n ) { hmm->nfwd = n; hmm->fwd = (double*) realloc(hmm->fwd, sizeof(double)*(hmm->nfwd+1)*hmm->nstates); } if ( !hmm->bwd ) { hmm->bwd = (double*) malloc(sizeof(double)*hmm->nstates); hmm->bwd_tmp = (double*) malloc(sizeof(double)*hmm->nstates); } // Init all states with equal likelihood int i,j,k, nstates = hmm->nstates; memcpy(hmm->fwd, hmm->state.fwd_prob, sizeof(*hmm->state.fwd_prob)*nstates); memcpy(hmm->bwd, hmm->state.bwd_prob, sizeof(*hmm->state.bwd_prob)*nstates); uint32_t prev_pos = hmm->state.snap_at_pos ? hmm->state.snap_at_pos : sites[0]; // New transition matrix: temporary values double *tmp_xi = (double*) calloc(nstates*nstates,sizeof(double)); double *tmp_gamma = (double*) calloc(nstates,sizeof(double)); double *fwd_bwd = (double*) malloc(sizeof(double)*nstates); // Run fwd for (i=0; ifwd[i*nstates]; double *fwd = &hmm->fwd[(i+1)*nstates]; double *eprob = &eprobs[i*nstates]; int pos_diff = sites[i] == prev_pos ? 0 : sites[i] - prev_pos - 1; _set_tprob(hmm, pos_diff); if ( hmm->set_tprob ) hmm->set_tprob(hmm, prev_pos, sites[i], hmm->set_tprob_data, hmm->curr_tprob); prev_pos = sites[i]; double norm = 0; for (j=0; jcurr_tprob,hmm->nstates,j,k); fwd[j] = pval * eprob[j]; norm += fwd[j]; } for (j=0; jbwd, *bwd_tmp = hmm->bwd_tmp; prev_pos = sites[n-1]; for (i=0; ifwd[(n-i)*nstates]; double *eprob = &eprobs[(n-i-1)*nstates]; int pos_diff = sites[n-i-1] == prev_pos ? 0 : prev_pos - sites[n-i-1] - 1; _set_tprob(hmm, pos_diff); if ( hmm->set_tprob ) hmm->set_tprob(hmm, sites[n-i-1], prev_pos, hmm->set_tprob_data, hmm->curr_tprob); prev_pos = sites[n-i-1]; double bwd_norm = 0; for (j=0; jcurr_tprob,hmm->nstates,k,j); bwd_tmp[j] = pval; bwd_norm += pval; } double norm = 0; for (j=0; jtprob_arr,hmm->nstates,k,j)*eprob[k] / norm; } } for (j=0; jcurr_tprob,nstates,k,j) = MAT(tmp_xi,nstates,k,j) / tmp_gamma[j]; norm += MAT(hmm->curr_tprob,nstates,k,j); } for (k=0; kcurr_tprob,nstates,k,j) /= norm; } free(tmp_gamma); free(tmp_xi); free(fwd_bwd); return hmm->curr_tprob; } void hmm_destroy(hmm_t *hmm) { free(hmm->init.vit_prob); free(hmm->init.fwd_prob); free(hmm->init.bwd_prob); free(hmm->state.vit_prob); free(hmm->state.fwd_prob); free(hmm->state.bwd_prob); free(hmm->vprob); free(hmm->vprob_tmp); free(hmm->vpath); free(hmm->curr_tprob); free(hmm->tmp); free(hmm->tprob_arr); free(hmm->fwd); free(hmm->bwd); free(hmm->bwd_tmp); free(hmm); } bcftools-1.21/HMM.h000066400000000000000000000116361467060157400140630ustar00rootroot00000000000000/* The MIT License Copyright (c) 2014-2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __HMM_H__ #define __HMM_H__ #define MAT(matrix,ndim,i,j) (matrix)[(ndim)*(i)+(j)] // P(i|j), that is, transition j->i typedef struct _hmm_t hmm_t; typedef void (*set_tprob_f) (hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob); /** * hmm_init() - initialize HMM * @nstates: number of states * @tprob: transition probabilities matrix (nstates x nstates), for elements ordering * see the MAT macro above. * @ntprob: number of precalculated tprob matrices or 0 for constant probs, independent * of distance */ hmm_t *hmm_init(int nstates, double *tprob, int ntprob); void hmm_set_tprob(hmm_t *hmm, double *tprob, int ntprob); #define HMM_VIT 1 #define HMM_FWD 2 #define HMM_BWD 4 /** * hmm_init_states() - initial state probabilities * @probs: initial state probabilities or NULL to reset to default * * If uncalled, all states are initialized with the same likelihood */ void hmm_init_states(hmm_t *hmm, double *probs); /** * hmm_snapshot() - take the model's snapshot, intended for sliding HMM * @snapshot: NULL or snapshot returned by previous hmm_snapshot() call, must be free()-ed by the caller * @pos: take the snapshot at this position * * If both restore() and snapshot() are needed, restore() must be called first. */ void *hmm_snapshot(hmm_t *hmm, void *snapshot, uint32_t pos); /** * hmm_restore() - restore model's snapshot, intended for sliding HMM * @snapshot: snapshot returned by hmm_snapshot() call or NULL to reset * @isite: take the snapshot at i-th step * * If both restore() and snapshot() are needed, restore() must be called first. */ void hmm_restore(hmm_t *hmm, void *snapshot); void hmm_reset(hmm_t *hmm, void *snapshot); /** * hmm_get_tprob() - return the array of transition matrices, precalculated * to ntprob positions. The first matrix is the initial tprob matrix * set by hmm_init() or hmm_set_tprob() */ double *hmm_get_tprob(hmm_t *hmm); int hmm_get_nstates(hmm_t *hmm); /** * hmm_set_tprob_func() - custom setter of transition probabilities */ void hmm_set_tprob_func(hmm_t *hmm, set_tprob_f set_tprob, void *data); /** * hmm_run_viterbi() - run Viterbi algorithm * @nsites: number of sites * @eprob: emission probabilities for each site and state (nsites x nstates) * @sites: list of positions * * When done, hmm->vpath[] contains the calculated Viterbi path. The states * are indexed starting from 0, a state at i-th site can be accessed as * vpath[nstates*i]. */ void hmm_run_viterbi(hmm_t *hmm, int nsites, double *eprob, uint32_t *sites); /** * hmm_get_viterbi_path() - the viterbi path: state at ith site is the * (nstates*isite)-th element */ uint8_t *hmm_get_viterbi_path(hmm_t *hmm); /** * hmm_run_fwd_bwd() - run the forward-backward algorithm * @nsites: number of sites * @eprob: emission probabilities for each site and state (nsites x nstates) * @sites: list of positions */ void hmm_run_fwd_bwd(hmm_t *hmm, int nsites, double *eprob, uint32_t *sites); /** * hmm_get_fwd_bwd_prob() - the probability of i-th state at j-th site can * be accessed as fwd_bwd[j*nstates+i]. */ double *hmm_get_fwd_bwd_prob(hmm_t *hmm); /** * hmm_run_baum_welch() - run one iteration of Baum-Welch algorithm * @nsites: number of sites * @eprob: emission probabilities for each site and state (nsites x nstates) * @sites: list of positions * * Same as hmm_run_fwd_bwd, in addition a pointer to a matrix with the new * transition probabilities is returned. In this version, emission * probabilities are not updated. */ double *hmm_run_baum_welch(hmm_t *hmm, int nsites, double *eprob, uint32_t *sites); void hmm_destroy(hmm_t *hmm); #endif bcftools-1.21/INSTALL000066400000000000000000000225371467060157400143240ustar00rootroot00000000000000For the impatient ================= The latest source code can be downloaded from github and compiled using: git clone --recurse-submodules https://github.com/samtools/htslib.git git clone https://github.com/samtools/bcftools.git cd bcftools # The following is optional: # autoheader && autoconf && ./configure --enable-libgsl --enable-perl-filters make IMPORTANT: --- In order to use the BCFtools plugins, this environment variable must be set and point to the correct location export BCFTOOLS_PLUGINS=/path/to/bcftools/plugins --- Note that if also the polysomy command or support for Perl filtering should be included, the compilation instructions differ, see Optional Compilation with GSL and Optional Compilation with Perl below. System Requirements =================== BCFtools and HTSlib depend on the following libraries: BCFtools: zlib gsl (optional, for the 'polysomy' command) libperl (optional, to support filters using perl syntax) HTSlib: zlib libbz2 liblzma libcurl (optional but strongly recommended, for network access) libcrypto (optional, for Amazon S3 support; not needed on MacOS) Building them requires development files to be installed on the build machine; note that MacOS and some Linux distributions package these separately from the library itself. See the "System Specific Details" below for guidance on how to install these on a variety of systems. The bzip2 and liblzma dependencies can be removed if full CRAM support is not needed - see HTSlib's INSTALL file for details. To build BCFtools, you will need: GNU make C compiler (e.g. gcc or clang) In addition, building the configure script requires: autoheader autoconf Running the configure script uses awk, along with a number of standard UNIX tools (cat, cp, grep, mv, rm, sed, among others). Almost all installations will have these already. Running the test harness (make test) uses: bash perl Building Configure ================== This step is only needed if configure.ac has been changed, or if configure does not exist (for example, when building from a git clone). The configure script and config.h.in can be built by running: autoheader autoconf If you have a full GNU autotools install, you can alternatively run: autoreconf Warnings like "AC_CONFIG_SUBDIRS: you should use literals" can be ignored or suppressed using 'autoconf -Wno-syntax'. Compilation =========== 'cd' to the bcftools directory containing the package's source and type: ./configure make If installing from a release (as opposed to from GitHub), the BCFtools release tarball contains a copy of HTSlib which will be used to build BCFtools. If you already have a system-installed HTSlib or another HTSlib that you would prefer to build against, you can arrange this by using the configure script's --with-htslib option. Use --with-htslib=DIR to point to an HTSlib source tree or installation in DIR (if the desired source tree has been configured to build in a separate build directory, DIR should refer to the build directory); or use --with-htslib=system to ignore any nearby HTSlib source tree and use only a system-installed HTSlib. When --with-htslib is not used, configure looks for an HTSlib source tree within or alongside the BCFtools source directory; if there are several likely candidates, you will have to use --with-htslib to choose one. When using make without running configure first, the directory ../htslib is used. Optional Compilation with Perl ============================== The '-i' and '-e' options can take external perl scripts for a more sophisticated filtering. This option can be enabled by supplying the --enable-perl-filters option to configure before running make: ./configure --enable-perl-filters Note that enabling this option changes the license from MIT to GPL because bcftools need to be built with perl -MExtUtils::Embed -e ccopts -e ldopts Note that when compiling on MacOS, the default options for linking with Perl provided by the system sometimes do not work. It was reported that removing the occurrence of -arch i386 from config.mk solved the problem. Optional Compilation with GSL ============================= The 'polysomy' command depends on the GNU Scientific Library (GSL) and is not enabled by default. In order to compile it, supply the --enable-libgsl option to configure before running make: ./configure --enable-libgsl The GNU Scientific Library depends on the cblas library. The configure script will look for both libcblas and libgslcblas, in that order. If you have more than one version of cblas installed and want to override its choice you can do this by using either --with-cblas=cblas or --with-cblas=gslcblas. Note that GSL is distributed under the GNU General Public License (GPL). When --enable-libgsl is used to compile bcftools, the resulting program will also be GPL licensed. If you want to distribute the program, you MUST do so under terms compatible with that license. A copy of the GPL is included in the LICENSE file, or can be downloaded from . In the default compilation mode the program is dual licensed and you may choose to be licensed under the terms of the MIT/Expat license or the GNU General Public License (GPL). Information on the GNU Scientific Library, including the rationale for its choice of license can be found at . Installation ============ Type 'make install' to install the bcftools executable and associated scripts and a manual page. The default is to install in /usr/local. This can be changed by using the configure script's --prefix option: ./configure --prefix=/path/to/install/dir The install target also understands DESTDIR and the other usual installation directory variables. The bgzip and tabix utilities are provided by HTSlib. If you have not also installed HTSlib separately, you may wish to install these utilities by hand by copying bcftools-1.x/htslib-1.x/{bgzip,tabix} to the same bin directory to which you have installed bcftools et al. System Specific Details ======================= Installing the prerequisites is system dependent and there is more than one correct way of satisfying these, including downloading them from source, compiling and installing them yourself. For people with super-user access, we provide an example set of commands below for installing the dependencies on a variety of operating system distributions. Note these are not specific recommendations on distribution, compiler or SSL implementation. It is assumed you already have the core set of packages for the given distribution - the lists may be incomplete if this is not the case. Intel Compiler -------------- At some optimisation levels the Intel compiler may use approximate floating point mathematics. We do not believe this to produce substantially erroneous results, but it can cause the test harness to fail due to minor fluctuations in the least significiant digits. If you wish to use icc with the test harness, it is recommended you use the "-fp-model precise" icc option. Debian / Ubuntu --------------- sudo apt-get update # Ensure the package list is up to date sudo apt-get install autoconf automake make gcc perl zlib1g-dev libbz2-dev liblzma-dev libcurl4-gnutls-dev libssl-dev libperl-dev libgsl0-dev Note: libcurl4-openssl-dev can be used as an alternative to libcurl4-gnutls-dev. RedHat / CentOS --------------- Note: To install gsl-devel, it may be necessary to enable the "crb" repository. dnf --enablerepo=crb install gsl-devel sudo yum install autoconf automake make gcc perl-Data-Dumper zlib-devel bzip2 bzip2-devel xz-devel curl-devel openssl-devel gsl-devel perl-ExtUtils-Embed Note: On some versions, Perl FindBin will need to be installed to make the tests work. sudo yum install perl-FindBin Alpine Linux ------------ Note: To install gsl-dev, it may be necessary to enable the "community" repository in /etc/apk/repositories. Note: some older Alpine versions use libressl-dev rather than openssl-dev. doas apk update # Ensure the package list is up to date doas apk add autoconf automake make gcc musl-dev perl bash zlib-dev bzip2-dev xz-dev curl-dev openssl-dev gsl-dev perl-dev OpenSUSE -------- sudo zypper install autoconf automake make gcc perl zlib-devel libbz2-devel xz-devel libcurl-devel libopenssl-devel gsl-devel MacOS, assuming Xcode is installed: ----- xz gsl (optional) Windows MSYS2/MINGW64 --------------------- The configure script must be used as without it the compilation will likely fail. Follow MSYS2 installation instructions at https://www.msys2.org/wiki/MSYS2-installation/ Then relaunch to MSYS2 shell using the "MSYS2 MinGW x64" executable. Once in that environment (check $MSYSTEM equals "MINGW64") install the compilers using pacman -S and the following package list: base-devel mingw-w64-x86_64-toolchain mingw-w64-x86_64-libdeflate mingw-w64-x86_64-zlib mingw-w64-x86_64-bzip2 mingw-w64-x86_64-xz mingw-w64-x86_64-curl mingw-w64-x86_64-autotools mingw-w64-x86_64-tools-git (The last is only needed for building libraries compatible with MSVC.) bcftools-1.21/LICENSE000066400000000000000000001201511467060157400142670ustar00rootroot00000000000000This software is available to you under a choice of one of two licenses. You may chose to be licensed under the terms of the MIT/Expat license or the GNU General Public License (GPL), both included below. If compiled with the GNU Scientific Library (which is optional and disabled by default as explained in the INSTALL document), the use of this software is governed by the GPL license. ----------------------------------------------------------------------------- The MIT/Expat License Copyright (C) 2012-2024 Genome Research Ltd. Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. 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For example, a copyright notice that reads "Copyright (C) 2005, 2007-2009, 2011-2012" should be interpreted as being identical to a notice that reads "Copyright (C) 2005, 2007, 2008, 2009, 2011, 2012" and a copyright notice that reads "Copyright (C) 2005-2012" should be interpreted as being identical to a notice that reads "Copyright (C) 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012".] ----------------------------------------------------------------------------- GNU GENERAL PUBLIC LICENSE Version 3, 29 June 2007 Copyright (C) 2007 Free Software Foundation, Inc. Everyone is permitted to copy and distribute verbatim copies of this license document, but changing it is not allowed. Preamble The GNU General Public License is a free, copyleft license for software and other kinds of works. The licenses for most software and other practical works are designed to take away your freedom to share and change the works. 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A "contributor" is a copyright holder who authorizes use under this License of the Program or a work on which the Program is based. The work thus licensed is called the contributor's "contributor version". A contributor's "essential patent claims" are all patent claims owned or controlled by the contributor, whether already acquired or hereafter acquired, that would be infringed by some manner, permitted by this License, of making, using, or selling its contributor version, but do not include claims that would be infringed only as a consequence of further modification of the contributor version. For purposes of this definition, "control" includes the right to grant patent sublicenses in a manner consistent with the requirements of this License. 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If, pursuant to or in connection with a single transaction or arrangement, you convey, or propagate by procuring conveyance of, a covered work, and grant a patent license to some of the parties receiving the covered work authorizing them to use, propagate, modify or convey a specific copy of the covered work, then the patent license you grant is automatically extended to all recipients of the covered work and works based on it. A patent license is "discriminatory" if it does not include within the scope of its coverage, prohibits the exercise of, or is conditioned on the non-exercise of one or more of the rights that are specifically granted under this License. You may not convey a covered work if you are a party to an arrangement with a third party that is in the business of distributing software, under which you make payment to the third party based on the extent of your activity of conveying the work, and under which the third party grants, to any of the parties who would receive the covered work from you, a discriminatory patent license (a) in connection with copies of the covered work conveyed by you (or copies made from those copies), or (b) primarily for and in connection with specific products or compilations that contain the covered work, unless you entered into that arrangement, or that patent license was granted, prior to 28 March 2007. Nothing in this License shall be construed as excluding or limiting any implied license or other defenses to infringement that may otherwise be available to you under applicable patent law. 12. No Surrender of Others' Freedom. If conditions are imposed on you (whether by court order, agreement or otherwise) that contradict the conditions of this License, they do not excuse you from the conditions of this License. If you cannot convey a covered work so as to satisfy simultaneously your obligations under this License and any other pertinent obligations, then as a consequence you may not convey it at all. For example, if you agree to terms that obligate you to collect a royalty for further conveying from those to whom you convey the Program, the only way you could satisfy both those terms and this License would be to refrain entirely from conveying the Program. 13. Use with the GNU Affero General Public License. Notwithstanding any other provision of this License, you have permission to link or combine any covered work with a work licensed under version 3 of the GNU Affero General Public License into a single combined work, and to convey the resulting work. The terms of this License will continue to apply to the part which is the covered work, but the special requirements of the GNU Affero General Public License, section 13, concerning interaction through a network will apply to the combination as such. 14. Revised Versions of this License. The Free Software Foundation may publish revised and/or new versions of the GNU General Public License from time to time. Such new versions will be similar in spirit to the present version, but may differ in detail to address new problems or concerns. Each version is given a distinguishing version number. If the Program specifies that a certain numbered version of the GNU General Public License "or any later version" applies to it, you have the option of following the terms and conditions either of that numbered version or of any later version published by the Free Software Foundation. If the Program does not specify a version number of the GNU General Public License, you may choose any version ever published by the Free Software Foundation. If the Program specifies that a proxy can decide which future versions of the GNU General Public License can be used, that proxy's public statement of acceptance of a version permanently authorizes you to choose that version for the Program. Later license versions may give you additional or different permissions. However, no additional obligations are imposed on any author or copyright holder as a result of your choosing to follow a later version. 15. Disclaimer of Warranty. THERE IS NO WARRANTY FOR THE PROGRAM, TO THE EXTENT PERMITTED BY APPLICABLE LAW. EXCEPT WHEN OTHERWISE STATED IN WRITING THE COPYRIGHT HOLDERS AND/OR OTHER PARTIES PROVIDE THE PROGRAM "AS IS" WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND PERFORMANCE OF THE PROGRAM IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE, YOU ASSUME THE COST OF ALL NECESSARY SERVICING, REPAIR OR CORRECTION. 16. Limitation of Liability. IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MODIFIES AND/OR CONVEYS THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS), EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. 17. Interpretation of Sections 15 and 16. If the disclaimer of warranty and limitation of liability provided above cannot be given local legal effect according to their terms, reviewing courts shall apply local law that most closely approximates an absolute waiver of all civil liability in connection with the Program, unless a warranty or assumption of liability accompanies a copy of the Program in return for a fee. END OF TERMS AND CONDITIONS How to Apply These Terms to Your New Programs If you develop a new program, and you want it to be of the greatest possible use to the public, the best way to achieve this is to make it free software which everyone can redistribute and change under these terms. To do so, attach the following notices to the program. It is safest to attach them to the start of each source file to most effectively state the exclusion of warranty; and each file should have at least the "copyright" line and a pointer to where the full notice is found. Copyright (C) This program is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this program. If not, see . Also add information on how to contact you by electronic and paper mail. If the program does terminal interaction, make it output a short notice like this when it starts in an interactive mode: Copyright (C) This program comes with ABSOLUTELY NO WARRANTY; for details type `show w'. This is free software, and you are welcome to redistribute it under certain conditions; type `show c' for details. The hypothetical commands `show w' and `show c' should show the appropriate parts of the General Public License. Of course, your program's commands might be different; for a GUI interface, you would use an "about box". You should also get your employer (if you work as a programmer) or school, if any, to sign a "copyright disclaimer" for the program, if necessary. For more information on this, and how to apply and follow the GNU GPL, see . The GNU General Public License does not permit incorporating your program into proprietary programs. If your program is a subroutine library, you may consider it more useful to permit linking proprietary applications with the library. If this is what you want to do, use the GNU Lesser General Public License instead of this License. But first, please read . ----------------------------------------------------------------------------- LICENSE FOR VariantKey (https://github.com/tecnickcom/variantkey) The MIT License Copyright (c) 2017-2018 GENOMICS plc Copyright (c) 2018-2023 Nicola Asuni - Tecnick.com Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. ----------------------------------------------------------------------------- LICENSE for utlist.h Copyright (c) 2007-2014, Troy D. Hanson http://troydhanson.github.com/uthash/ All rights reserved. Redistribution and use in source and binary forms, with or without modification, are permitted provided that the following conditions are met: * Redistributions of source code must retain the above copyright notice, this list of conditions and the following disclaimer. THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. ----------------------------------------------------------------------------- License for edlib.[ch] The MIT License (MIT) Copyright (c) 2014 Martin Šošić Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. bcftools-1.21/Makefile000066400000000000000000000430341467060157400147260ustar00rootroot00000000000000# Makefile for bcftools, utilities for Variant Call Format VCF/BCF files. # # Copyright (C) 2012-2021 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. CC = gcc AR = ar RANLIB = ranlib CPPFLAGS = CFLAGS = -g -Wall -O2 LDFLAGS = LIBS = DYNAMIC_FLAGS = -rdynamic PLUGINS_ENABLED = yes PLUGIN_EXT = .so OBJS = main.o vcfindex.o tabix.o \ vcfstats.o vcfisec.o vcfmerge.o vcfquery.o vcffilter.o filter.o vcfsom.o \ vcfnorm.o vcfgtcheck.o vcfview.o vcfannotate.o vcfroh.o vcfconcat.o \ vcfcall.o mcall.o vcmp.o gvcf.o reheader.o convert.o vcfconvert.o tsv2vcf.o \ vcfcnv.o vcfhead.o HMM.o consensus.o ploidy.o bin.o hclust.o version.o \ regidx.o smpl_ilist.o csq.o vcfbuf.o \ mpileup.o bam2bcf.o bam2bcf_indel.o bam2bcf_iaux.o bam2bcf_edlib.o \ read_consensus.o bam_sample.o \ vcfsort.o cols.o extsort.o dist.o abuf.o \ ccall.o em.o prob1.o kmin.o str_finder.o gff.o edlib.o PLUGIN_OBJS = vcfplugin.o prefix = /usr/local exec_prefix = $(prefix) bindir = $(exec_prefix)/bin libdir = $(exec_prefix)/lib libexecdir = $(exec_prefix)/libexec mandir = $(prefix)/share/man man1dir = $(mandir)/man1 # Installation location for $(PLUGINS) plugindir = $(libexecdir)/bcftools pluginpath = $(plugindir) # Installation location for $(MISC_PROGRAMS) and $(MISC_SCRIPTS) misc_bindir = $(bindir) MKDIR_P = mkdir -p INSTALL = install -p INSTALL_DATA = $(INSTALL) -m 644 INSTALL_DIR = $(MKDIR_P) -m 755 INSTALL_MAN = $(INSTALL_DATA) INSTALL_PROGRAM = $(INSTALL) INSTALL_SCRIPT = $(INSTALL_PROGRAM) PROGRAMS = bcftools MISC_SCRIPTS = \ misc/color-chrs.pl \ misc/gff2gff.py \ misc/guess-ploidy.py \ misc/plot-vcfstats \ misc/plot-roh.py \ misc/run-roh.pl \ misc/vcfutils.pl TEST_PROGRAMS = test/test-rbuf test/test-regidx ALL_CPPFLAGS = -I. $(HTSLIB_CPPFLAGS) $(CPPFLAGS) ALL_LDFLAGS = $(HTSLIB_LDFLAGS) $(LDFLAGS) ALL_LIBS = -lz $(DL_LIBS) $(LIBS) all: $(PROGRAMS) $(TEST_PROGRAMS) plugins EXTRA_CPPFLAGS = GSL_LIBS = # On windows, plugins need to be fully linked. This adds the extra libraries # needed. Defined here so config.mk can override it. W32_PLUGIN_LIBS = libbcftools.a $(HTSLIB_DLL) $(ALL_LIBS) # Usually config.mk and config.h are generated by running configure # or config.status, but if those aren't used create defaults here. config.mk: @sed -e '/^prefix/,/^PLUGIN_EXT/d;s/@Hsource@//;s/@Hinstall@/#/;s#@HTSDIR@#../htslib#g;s/@HTSLIB_CPPFLAGS@/-I$$(HTSDIR)/g;' config.mk.in > $@ config.h: echo '/* Basic config.h generated by Makefile */' > $@ ifneq "$(PLUGINS_ENABLED)" "no" echo '#define ENABLE_BCF_PLUGINS 1' >> $@ echo '#define PLUGIN_EXT "$(PLUGIN_EXT)"' >> $@ endif include config.mk PACKAGE_VERSION = 1.21 # If building from a Git repository, replace $(PACKAGE_VERSION) with the Git # description of the working tree: either a release tag with the same value # as $(PACKAGE_VERSION) above, or an exact description likely based on a tag. # $(shell), :=, etc are GNU Make-specific. If you don't have GNU Make, # comment out this conditional. ifneq "$(wildcard .git)" "" PACKAGE_VERSION := $(shell git describe --always --dirty) DOC_VERSION := $(shell git describe --always)+ DOC_DATE := $(shell date +'%Y-%m-%d %R %Z') # Force version.h to be remade if $(PACKAGE_VERSION) has changed. version.h: $(if $(wildcard version.h),$(if $(findstring "$(PACKAGE_VERSION)",$(shell cat version.h)),,force)) endif # If you don't have GNU Make but are building from a Git repository, you may # wish to replace this with a rule that always rebuilds version.h: # version.h: force # echo '#define BCFTOOLS_VERSION "`git describe --always --dirty`"' > $@ version.h: echo '#define BCFTOOLS_VERSION "$(PACKAGE_VERSION)"' > $@ print-version: @echo $(PACKAGE_VERSION) .SUFFIXES: .c .o .c.o: $(CC) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) -c -o $@ $< # The polysomy command is not compiled by default because it brings dependency # on libgsl. The command can be compiled with `make USE_GPL=1`. See the INSTALL # and LICENSE documents to understand license implications. ifdef USE_GPL main.o : EXTRA_CPPFLAGS += -DUSE_GPL OBJS += polysomy.o peakfit.o ifndef GSL_LIBS GSL_LIBS += -lgsl -lcblas endif endif print-%: @echo '$*=$($*)' # Plugin rules ifneq "$(PLUGINS_ENABLED)" "no" PLUGINC = $(foreach dir, plugins, $(wildcard $(dir)/*.c)) PLUGINS = $(PLUGINC:.c=$(PLUGIN_EXT)) PLUGINM = $(PLUGINC:.c=.mk) OBJS += $(PLUGIN_OBJS) ifneq "$(origin PLATFORM)" "file" PLATFORM := $(shell uname -s) endif ifeq "$(PLATFORM)" "Darwin" $(PLUGINS): | bcftools PLUGIN_FLAGS = -bundle -bundle_loader bcftools -Wl,-undefined,dynamic_lookup DL_LIBS = else ifeq "$(PLATFORM)" "CYGWIN" $(PLUGINS): | bcftools PLUGIN_FLAGS = -fPIC -shared PLUGIN_LIBS = $(W32_PLUGIN_LIBS) DL_LIBS = -ldl else ifneq "$(filter MINGW% MSYS%,$(PLATFORM))" "" DYNAMIC_FLAGS = $(PLUGINS): | bcftools PLUGIN_FLAGS = -fPIC -shared -Wl,-export-all-symbols PLUGIN_LIBS = $(W32_PLUGIN_LIBS) # On windows, plugins need to be fully linked, including bcftools_version() symbol # from the application they will be loaded into. DL_LIBS = else PLUGIN_FLAGS = -fPIC -shared ifeq "$(PLATFORM)" "default" # Configure was used and has already added -ldl to $(LIBS) if necessary DL_LIBS = else DL_LIBS = -ldl endif endif libbcftools.a: $(OBJS) @-rm -f $@ $(AR) -rc $@ $(OBJS) -$(RANLIB) $@ vcfplugin.o: EXTRA_CPPFLAGS += -DPLUGINPATH='"$(pluginpath)"' %.dll %.cygdll: %.c version.h version.c libbcftools.a $(HTSLIB_DLL) $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(PLUGIN_LIBS) %.so: %.c version.h version.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(LIBS) -include $(PLUGINM) test check: test-plugins else # PLUGINS_ENABLED PLUGINC = PLUGINS = PLUGINM = test check: test-no-plugins endif # PLUGINS_ENABLED bcftools: $(OBJS) $(HTSLIB) $(CC) $(DYNAMIC_FLAGS) $(ALL_LDFLAGS) -o $@ $(OBJS) $(HTSLIB_LIB) -lm $(ALL_LIBS) $(GSL_LIBS) $(PERL_LIBS) -lpthread plugins: $(PLUGINS) bcftools_h = bcftools.h $(htslib_hts_defs_h) $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) call_h = call.h $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) vcmp.h variantkey_h = variantkey.h hex.h convert_h = convert.h $(htslib_vcf_h) tsv2vcf_h = tsv2vcf.h $(htslib_vcf_h) filter_h = filter.h $(htslib_vcf_h) gvcf_h = gvcf.h $(bcftools_h) khash_str2str_h = khash_str2str.h $(htslib_khash_h) ploidy_h = ploidy.h regidx.h prob1_h = prob1.h $(htslib_vcf_h) $(call_h) smpl_ilist_h = smpl_ilist.h $(htslib_vcf_h) vcfbuf_h = vcfbuf.h $(htslib_vcf_h) abuf_h = abuf.h $(htslib_vcf_h) dbuf_h = dbuf.h $(htslib_vcf_h) bam2bcf_h = bam2bcf.h $(htslib_hts_h) $(htslib_vcf_h) bam_sample_h = bam_sample.h $(htslib_sam_h) cigar_state_h = cigar_state.h $(htslib_hts_h) $(htslib_sam_h) read_consensus_h = read_consensus.h $(htslib_hts_h) $(htslib_sam_h) str_finder_h = str_finder.h utlist.h str_finder.o: str_finder.c $(str_finder_h) utlist.h main.o: main.c $(htslib_hts_h) config.h version.h $(bcftools_h) vcfannotate.o: vcfannotate.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(htslib_khash_str2int_h) $(bcftools_h) vcmp.h $(filter_h) $(convert_h) $(smpl_ilist_h) regidx.h $(htslib_khash_h) $(dbuf_h) vcfplugin.o: vcfplugin.c config.h $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(htslib_khash_str2int_h) $(bcftools_h) vcmp.h $(filter_h) vcfcall.o: vcfcall.c $(htslib_vcf_h) $(htslib_kfunc_h) $(htslib_synced_bcf_reader_h) $(htslib_khash_str2int_h) $(bcftools_h) $(call_h) $(prob1_h) $(ploidy_h) $(gvcf_h) regidx.h $(vcfbuf_h) vcfconcat.o: vcfconcat.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(htslib_bgzf_h) $(htslib_tbx_h) $(htslib_thread_pool_h) $(htslib_hts_endian_h) $(bcftools_h) vcfconvert.o: vcfconvert.c $(htslib_faidx_h) $(htslib_vcf_h) $(htslib_bgzf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_kseq_h) $(htslib_hts_endian_h) $(bcftools_h) $(filter_h) $(convert_h) $(tsv2vcf_h) vcffilter.o: vcffilter.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) rbuf.h regidx.h vcfgtcheck.o: vcfgtcheck.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_kbitset_h) $(htslib_hts_os_h) $(htslib_bgzf_h) $(bcftools_h) extsort.h $(filter_h) vcfindex.o: vcfindex.c $(htslib_vcf_h) $(htslib_tbx_h) $(htslib_kstring_h) $(htslib_bgzf_h) $(bcftools_h) vcfisec.o: vcfisec.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_hts_os_h) $(htslib_hts_defs_h) $(bcftools_h) $(filter_h) vcfmerge.o: vcfmerge.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_faidx_h) $(htslib_kbitset_h) $(htslib_hts_endian_h) $(bcftools_h) regidx.h vcmp.h $(htslib_khash_h) vcfnorm.o: vcfnorm.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_faidx_h) $(htslib_khash_str2int_h) $(bcftools_h) rbuf.h abuf.h gff.h regidx.h $(filter_h) vcfquery.o: vcfquery.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_khash_str2int_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) $(convert_h) $(smpl_ilist_h) vcfroh.o: vcfroh.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kstring_h) $(htslib_kseq_h) $(htslib_bgzf_h) $(bcftools_h) HMM.h $(smpl_ilist_h) $(filter_h) vcfcnv.o: vcfcnv.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kstring_h) $(htslib_kfunc_h) $(htslib_khash_str2int_h) $(htslib_hts_defs_h) $(bcftools_h) HMM.h rbuf.h vcfhead.o: vcfhead.c $(htslib_kstring_h) $(htslib_vcf_h) $(bcftools_h) vcfsom.o: vcfsom.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_hts_os_h) $(htslib_hts_defs_h) $(bcftools_h) vcfsort.o: vcfsort.c $(htslib_vcf_h) $(htslib_kstring_h) $(htslib_hts_os_h) $(htslib_hts_defs_h) $(htslib_bgzf_h) kheap.h $(bcftools_h) vcfstats.o: vcfstats.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_faidx_h) $(bcftools_h) $(filter_h) bin.h dist.h vcfview.o: vcfview.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) $(htslib_khash_str2int_h) $(htslib_kbitset_h) reheader.o: reheader.c $(htslib_vcf_h) $(htslib_bgzf_h) $(htslib_tbx_h) $(htslib_kseq_h) $(htslib_thread_pool_h) $(htslib_faidx_h) $(htslib_khash_str2int_h) $(bcftools_h) $(khash_str2str_h) tabix.o: tabix.c $(htslib_bgzf_h) $(htslib_tbx_h) ccall.o: ccall.c $(htslib_kfunc_h) $(call_h) kmin.h $(prob1_h) convert.o: convert.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_kfunc_h) $(htslib_khash_str2int_h) $(htslib_hts_endian_h) $(bcftools_h) $(variantkey_h) $(convert_h) $(filter_h) tsv2vcf.o: tsv2vcf.c $(tsv2vcf_h) em.o: em.c $(htslib_vcf_h) kmin.h $(call_h) filter.o: filter.c $(htslib_khash_str2int_h) $(htslib_hts_defs_h) $(htslib_vcfutils_h) $(htslib_kfunc_h) $(htslib_hts_endian_h) config.h $(filter_h) $(bcftools_h) $(CC) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(PERL_CFLAGS) -c -o $@ $< gvcf.o: gvcf.c $(gvcf_h) $(bcftools_h) kmin.o: kmin.c kmin.h mcall.o: mcall.c $(htslib_kfunc_h) $(htslib_khash_str2int_h) $(call_h) $(prob1_h) prob1.o: prob1.c $(prob1_h) vcmp.o: vcmp.c $(htslib_hts_h) $(htslib_vcf_h) vcmp.h ploidy.o: ploidy.c $(htslib_khash_str2int_h) $(htslib_kseq_h) $(htslib_hts_h) $(bcftools_h) $(ploidy_h) polysomy.o: polysomy.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_hts_defs_h) $(bcftools_h) peakfit.h peakfit.o: peakfit.c peakfit.h $(htslib_hts_h) $(htslib_kstring_h) bin.o: bin.c $(bcftools_h) bin.h dist.o: dist.c dist.h cols.o: cols.c cols.h regidx.o: regidx.c $(htslib_hts_h) $(htslib_kstring_h) $(htslib_kseq_h) $(htslib_khash_str2int_h) regidx.h consensus.o: consensus.c $(htslib_vcf_h) $(htslib_kstring_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(htslib_bgzf_h) regidx.h $(bcftools_h) rbuf.h $(filter_h) $(smpl_ilist_h) mpileup.o: mpileup.c $(htslib_sam_h) $(htslib_faidx_h) $(htslib_kstring_h) $(htslib_khash_str2int_h) $(htslib_hts_os_h) regidx.h $(bcftools_h) $(bam2bcf_h) $(bam_sample_h) $(gvcf_h) bam2bcf.o: bam2bcf.c $(htslib_hts_h) $(htslib_sam_h) $(htslib_kstring_h) $(htslib_kfunc_h) $(bam2bcf_h) mw.h bam2bcf_indel.o: bam2bcf_indel.c $(htslib_hts_h) $(htslib_sam_h) $(htslib_khash_str2int_h) $(bam2bcf_h) $(htslib_ksort_h) $(str_finder_h) bam2bcf_iaux.o: bam2bcf_iaux.c $(htslib_hts_h) $(htslib_sam_h) $(htslib_khash_str2int_h) $(bcftools_h) $(bam2bcf_h) $(htslib_ksort_h) $(read_consensus_h) $(cigar_state_h) bam2bcf_edlib.o: bam2bcf_edlib.c $(htslib_hts_h) $(htslib_sam_h) $(htslib_khash_str2int_h) $(bam2bcf_h) $(str_finder_h) $(htslib_ksort_h) edlib.h read_consensus.o: read_consensus.c $(read_consensus_h) $(cigar_state_h) $(bcftools_h) kheap.h bam_sample.o: bam_sample.c $(htslib_hts_h) $(htslib_kstring_h) $(htslib_khash_str2int_h) $(khash_str2str_h) $(bam_sample_h) $(bcftools_h) version.o: version.h version.c hclust.o: hclust.c $(htslib_hts_h) $(htslib_kstring_h) $(bcftools_h) hclust.h HMM.o: HMM.c $(htslib_hts_h) HMM.h vcfbuf.o: vcfbuf.c $(htslib_vcf_h) $(htslib_vcfutils_h) $(htslib_hts_os_h) $(htslib_kbitset_h) $(bcftools_h) $(vcfbuf_h) rbuf.h abuf.o: abuf.c $(htslib_vcf_h) $(bcftools_h) rbuf.h abuf.h edlib.o: edlib.c edlib.h extsort.o: extsort.c $(bcftools_h) extsort.h kheap.h smpl_ilist.o: smpl_ilist.c $(bcftools_h) $(smpl_ilist_h) gff.o: gff.c $(htslib_hts_h) $(htslib_khash_h) $(htslib_khash_str2int_h) $(htslib_kseq_h) $(htslib_bgzf_h) $(bcftools_h) gff.h regidx.h csq.o: csq.c $(htslib_hts_h) $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_khash_h) $(htslib_khash_str2int_h) $(htslib_kseq_h) $(htslib_faidx_h) $(htslib_bgzf_h) $(bcftools_h) $(filter_h) regidx.h kheap.h $(smpl_ilist_h) rbuf.h gff.h # test programs # For tests that might use it, set $REF_PATH explicitly to use only reference # areas within the test suite (or set it to ':' to use no reference areas). # (regression.sh sets $REF_PATH to a subdirectory itself.) # # If using MSYS, avoid poor shell expansion via: # MSYS2_ARG_CONV_EXCL="*" make check check-no-plugins test-no-plugins: $(PROGRAMS) $(TEST_PROGRAMS) $(BGZIP) $(TABIX) ./test/test-rbuf ./test/test-regidx REF_PATH=: ./test/test.pl --exec bgzip=$(BGZIP) --exec tabix=$(TABIX) --htsdir=$(HTSDIR) $${TEST_OPTS:-} check-plugins test-plugins: $(PROGRAMS) $(TEST_PROGRAMS) $(BGZIP) $(TABIX) plugins ./test/test-rbuf ./test/test-regidx REF_PATH=: ./test/test.pl --plugins --exec bgzip=$(BGZIP) --exec tabix=$(TABIX) --htsdir=$(HTSDIR) $${TEST_OPTS:-} # test HTSlib as well, where it is built alongside BCFtools check-all test-all: test-htslib test test/test-rbuf.o: test/test-rbuf.c rbuf.h test/test-rbuf: test/test-rbuf.o $(CC) $(LDFLAGS) -o $@ $^ $(ALL_LIBS) test/test-regidx.o: test/test-regidx.c $(htslib_kstring_h) $(htslib_hts_os_h) $(htslib_hts_defs_h) regidx.h test/test-regidx: test/test-regidx.o regidx.o | $(HTSLIB) $(CC) $(ALL_LDFLAGS) -o $@ $^ $(HTSLIB_LIB) -lpthread $(ALL_LIBS) # make docs target depends the a2x asciidoc program doc/bcftools.1: doc/bcftools.txt cd doc && asciidoctor -adate="$(DOC_DATE)" -aversion=$(DOC_VERSION) -b manpage -a linkcss -a stylesheet=docbook-xsl.css bcftools.txt doc/bcftools.html: doc/bcftools.txt cd doc && asciidoctor -adate="$(DOC_DATE)" -aversion=$(DOC_VERSION) -b html5 -a linkcss -a stylesheet=docbook-xsl.css bcftools.txt docs: doc/bcftools.1 doc/bcftools.html # To avoid an install dependency on asciidoc, the make install target # does not depend on doc/bcftools.1 # bcftools.1 is a generated file from the asciidoc bcftools.txt file. # Since there is no make dependency, bcftools.1 can be out-of-date and # make docs can be run to update if asciidoc is available install: $(PROGRAMS) $(PLUGINS) $(INSTALL_DIR) $(DESTDIR)$(bindir) $(DESTDIR)$(man1dir) $(DESTDIR)$(plugindir) $(INSTALL_PROGRAM) $(PROGRAMS) $(DESTDIR)$(bindir) $(INSTALL_SCRIPT) $(MISC_SCRIPTS) $(DESTDIR)$(misc_bindir) $(INSTALL_MAN) doc/bcftools.1 $(DESTDIR)$(man1dir) $(INSTALL_PROGRAM) plugins/*$(PLUGIN_EXT) $(DESTDIR)$(plugindir) clean: testclean clean-plugins -rm -f gmon.out *.o *.a *~ $(PROGRAMS) version.h -rm -rf *.dSYM test/*.dSYM clean-plugins: -rm -f plugins/*$(PLUGIN_EXT) plugins/*.P -rm -rf plugins/*.dSYM testclean: -rm -f test/*.o test/*.fa.fai test/*~ $(TEST_PROGRAMS) -rm -f test/*.unsorted.hex test/*.unsorted.tsv distclean: clean -rm -f config.cache config.h config.log config.mk config.status -rm -rf autom4te.cache -rm -f TAGS clean-all: clean clean-htslib distclean-all: distclean distclean-htslib testclean-all: testclean testclean-htslib tags: ctags -f TAGS *.[ch] plugins/*.[ch] force: .PHONY: all check check-all clean clean-all clean-plugins .PHONY: distclean distclean-all force install .PHONY: print-version tags test test-all testclean testclean-all plugins docs bcftools-1.21/NEWS000066400000000000000000002165641467060157400137770ustar00rootroot00000000000000## Release 1.21 (12th September 2024) Changes affecting the whole of bcftools, or multiple commands: * Support multiple semicolon-separated strings when filtering by ID using -i/-e (#2190). For example, `-i 'ID="rs123"'` now correctly matches `rs123;rs456` * The filtering expression ILEN can be positive (insertion), negative (deletion), zero (balanced substitutions), or set to missing value (symbolic alleles). * bcftools query * bcftools +split-vep - The columns indices printed by default with `-H` (e.g., "#[1]CHROM") can be now suppressed by giving the option twice `-HH` (#2152) Changes affecting specific commands: * bcftools annotate - Support dynamic variables read from a tab-delimited annotation file (#2151) For example, in the two cases below the field 'STR' from the -a file is required to match the INFO/TAG in VCF. In the first example the alleles REF,ALT must match, in the second example they are ignored. The option -k is required to output also records that were not annotated: bcftools annotate -a ann.tsv.gz -c CHROM,POS,REF,ALT,SCORE,~STR -i'TAG={STR}' -k in.vcf bcftools annotate -a ann.tsv.gz -c CHROM,POS,-,-,SCORE,~STR -i'TAG={STR}' -k in.vcf - When adding Type=String annotations from a tab-delimited file, encode characters with special meaning using percent encoding (';', '=' in INFO and ':' in FORMAT) (#2202) * bcftools consensus - Allow to apply a reference allele which overlaps a previous deletion, there is no need to complain about overlapping alleles in such case - Fix a bug which required `-s -` to be present even when there were no samples in the VCF (#2260) * bcftools csq - Fix a rare bug where indel combined with a substitution ending at exon boundary is incorrectly predicted to have 'inframe' rather than 'frameshift' consequence (#2212) * bcftools gtcheck - Fix a segfault with --no-HWE-prob. The bug was introduced with the output format change in 1.19 which replaced the DC section with DCv2 (#2180) - The number of matching genotypes in the DCv2 output was not calculated correctly with non-zero `-E, --error-probability`. Consequently, also the average HWE score was incorrect. The main output, the discordance score, was not affected by the bug * bcftools +mendelian2 - Include the number of good cases where at least one of the trio genotypes has an alternate allele (#2204) - Fix the error message which would report the wrong sample when non-existent sample is given. Note that bug only affected the error message, the program otherwise assigns the family members correctly (#2242) * bcftools merge - Fix a severe bug in merging of FORMAT fields with Number=R and Number=A values. For example, rows with high-coverage FORMAT/AD values (bigger or equal to 128) could have been assigned to incorrect samples. The bug was introduced in version 1.19. For details see #2244. * bcftools mpileup - Return non-zero error code when the input BAM/CRAM file is truncated (#2177) - Add FORMAT/AD annotation by default, disable with `-a -AD` * bcftools norm - Support realignment of symbolic alleles, similarly to added previously (#1919,#2145) - Fix in reporting reference allele genotypes with `--multi-overlaps .` (#2160) - Support of duplicate removal of symbolic alleles of the same type but different SVLEN (#2182) - New `-S, --sort` switch to optionally sort output records by allele (#1484) - Add the `-i/-e` filtering options to select records for normalization. Note duplicate removal ignores this option. - Fix a bug where `--atomize` would not fill GT alleles for atomized SNVs followed by an indel (#2239) * bcftools +remove-overlaps - Revamp the program to allow greater flexibility, with the following new options: -M, --mark-tag TAG Mark -m sites with INFO/TAG -m, --mark EXPR Mark (if also -M is present) or remove sites [overlap] dup .. all overlapping sites overlap .. overlapping sites min(QUAL) .. mark sites with lowest QUAL until overlaps are resolved --missing EXPR Value to use for missing tags with -m 'min(QUAL)' 0 .. the default DP .. heuristics, scale maximum QUAL value proportionally to INFO/DP --reverse Apply the reverse logic, for example preserve duplicates instead of removing -O, --output-type t t: plain list of sites (chr,pos), tz: compressed list * bcftools +tag2tag - The conversions --LXX-to-XX, --XX-to-LXX were working but specific cases such as --LAD-to-AD were not. - Print more informative error message when source tag type violiates VCF specification * bcftools +trio-dnm2 - Better handling of the --strictly-novel functionality, especically with respect to chrX inheritance ## Release 1.20 (15th April 2024) Changes affecting the whole of bcftools, or multiple commands: * Add short option -W for --write-index. The option now accepts an optional parameter which allows to choose between TBI and CSI index format. Changes affecting specific commands: * bcftools consensus - Add new --regions-overlap option which allows to take into account overlapping deletions that start out of the fasta file target region. * bcftools isec - Add new option `-l, --file-list` to read the list of file names from a file * bcftools merge - Add new option `--force-single` to support single-file edge case (#2100) * bcftools mpileup - Add new option --indels-cns for an alternative indel calling model, which should increase the speed on long read data (thanks to using edlib) and the precision (thanks to a number of heuristics). * bcftools norm - Change the order of atomization and multiallelic splitting (when both -a,-m are given) from "atomize first, then split" to "split first, then atomize". This usually results in a simpler VCF representation. The previous behaviour can be achieved by explicitly streaming the output of the --atomize command into the --multiallelics splitting command. - Fix Type=String multiallelic splitting for Number=A,R,G tags with incorrect number of values. - Merging into multiallelic sites with `bcftools norm -m +indels` did not work. This is now fixed and the merging is now more strict about variant types, for example complex events, such as AC>TGA, are not considered as indels anymore (#2084) * bcftools reheader - Allow reading the input file from a stream with --fai (#2088) * bcftools +setGT - Support for custom genotypes based on the allele with higher depth, such as `--new-gt c:0/X` custom genotypes (#2065) * bcftools +split-vep - When only one of the tags is present, automatically choose INFO/BCSQ (the default tag name produced by `bcftools csq`) or INFO/CSQ (produced by VEP). When both tags are present, use the default INFO/CSQ. - Transcript selection by MANE, PICK, and user-defined transcripts, for example --select CANONICAL=YES --select MANE_SELECT!="" --select PolyPhen~probably_damaging - Select all matching transcripts via --select, not just one - Change automatic type parsing of VEP fields DNA_position, CDS_position, and Protein_position from Integer to String, as it can be of the form "8586-8599/9231". The type Integer can be still enforced with `-c cDNA_position:int,CDS_position:int,Protein_position:int`. - Recognize `-c field:str`, not just `-c field:string`, as advertised in the usage page - Fix a bug which made filtering expression containing missing values crash (#2098) * bcftools stats - When GT is missing but AD is present, the program determines the alternate allele from AD. However, if the AD tag has incorrect number of values, the program would exit with an error printing "Requested allele outside valid range". This is now fixed by taking into account the actual number of ALT alleles. * bcftools +tag2tag - Support for conversion from tags using localized alleles (e.g. LPL, LAD) to the family of standard tags (PL, AD) * bcftools +trio-dnm2 - Extend --strictly-novel to exclude cases where the non-Mendelian allele is the reference allele. The change is motivated by the observation that this class of variants is enriched for errors (especially for indels), and better corresponds with the option name. ## Release 1.19 (12th December 2023) Changes affecting the whole of bcftools, or multiple commands: * Filtering expressions can be given a file with list of strings to match, this was previously possible only for the ID column. For example ID=@file .. selects lines with ID present in the file INFO/TAG=@file.txt .. selects lines where TAG has a string value listed in the file INFO/TAG!=@file.txt .. TAG must not have a string value listed in the file Allow to query REF,ALT columns directly, for example -e 'REF="N"' Changes affecting specific commands: * bcftools annotate - Fix `bcftools annotate --mark-sites`, VCF sites overlapping regions in a BED file were not annotated (#1989) - Add flexibility to FILTER column transfers and allow transfers within the same file, across files, and in combination. For examples see http://samtools.github.io/bcftools/howtos/annotate.html#transfer_filter_to_info * bcftools call - Output MIN_DP rather than MinDP in gVCF mode - New `-*, --keep-unseen-allele` option to output the unobserved allele <*>, intended for gVCF. * bcftools head - New `-s, --samples` option to include the #CHROM header line with samples. * bcftools gtcheck - Add output options `-o, --output` and `-O, --output-type` - Add filtering options `-i, --include` and `-e, --exclude` - Rename the short option `-e, --error-probability` from lower case to upper case `-E, --error-probability` - Changes to the output format, replace the DC section with DCv2: - adds a new column for the number of matching genotypes - The --error-probability is newly interpreted as the probability of erroneous allele rather than genotype. In other words, the calculation of the discordance score now considers the probability of genotyping error to be different for HOM and HET genotypes, i.e. P(0/1|dsg=0) > P(1/1|dsg=0). - fixes in HWE score calculation plus output average HWE score rather than absolute HWE score - better description of fields * bcftools merge - Add `-m` modifiers to suppress the output of the unseen allele <*> or at variant sites (e.g. `-m both,*`) or all sites (e.g. `-m both,**`) * bcftools mpileup - Output MIN_DP rather than MinDP in gVCF mode * bcftools norm - Add the number of joined lines to the summary output, for example Lines total/split/joined/realigned/skipped: 6/0/3/0/0 - Allow combining -m and -a with --old-rec-tag (#2020) - Symbolic alleles caused norm to expand REF to the full length of the deletion. This was not intended and problematic for long deletions, the REF allele should list one base only (#2029) * bcftools query - Add new `-N, --disable-automatic-newline` option for pre-1.18 query formatting behavior when newline would not be added when missing - Make the automatic addition of the newline character in a more predictable way and, when missing, always put it at the end of the expression. In version 1.18 it could be added at the end of the expression (for per-site expressions) or inside the square brackets (for per-sample expressions). The new behavior is: - if the formatting expression contains a newline character, do nothing - if there is no newline character and -N, --disable-automatic-newline is given, do nothing - if there is no newline character and -N is not given, insert newline at the end of the expression See #1969 for details - Add new `-F, --print-filtered` option to output a default string for samples that would otherwise be filtered by `-i/-e` expressions. - Include sample name in the output header with `-H` whenever it makes sense (#1992) * bcftools +spit-vep - Fix on the fly filtering involving numeric subfields, e.g. `-i 'MAX_AF<0.001'` (#2039) - Interpret default column type names (--columns-types) as entire strings, rather than substrings to avoid unexpected spurious matches (i.e. internally add ^ and $ to all field names) * bcftools +trio-dnm2 - Do not flag paternal genotyping errors as de novo mutations. Specifically, when father's chrX genotype is 0/1 and mother's 0/0, 0/1 in the child will not be marked as DNM. * bcftools view - Add new `-A, --trim-unseen-allele` option to remove the unseen allele <*> or at variant sites (`-A`) or all sites (`-AA`) ## Release 1.18 (25th July 2023) Changes affecting the whole of bcftools, or multiple commands: * Support auto indexing during writing BCF and VCF.gz via new `--write-index` option Changes affecting specific commands: * bcftools annotate - The `-m, --mark-sites` option can be now used to mark all sites without the need to provide the `-a` file (#1861) - Fix a bug where the `-m` function did not respect the `--min-overlap` option (#1869) - Fix a bug when update of INFO/END results in assertion error (#1957) * bcftools concat - New option `--drop-genotypes` * bcftools consensus - Support higher-ploidy genotypes with `-H, --haplotype` (#1892) - Allow `--mark-ins` and `--mark-snv` with a character, similarly to `--mark-del` * bcftools convert - Support for conversion from tab-delimited files (CHROM,POS,REF,ALT) to sites-only VCFs * bcftools csq - New `--unify-chr-names` option to automatically unify different chromosome naming conventions in the input GFF, fasta and VCF files (e.g. "chrX" vs "X") - More versatility in parsing various flavors of GFF - A new `--dump-gff` option to help with debugging and investigating the internals of hGFF parsing - When printing consequences in nonsense mediated decay transcripts, include 'NMD_transcript' in the consequence part of the annotation. This is to make filtering easier and analogous to VEP annotations. For example the consequence annotation 3_prime_utr|PCGF3|ENST00000430644|NMD is newly printed as 3_prime_utr&NMD_transcript|PCGF3|ENST00000430644|NMD * bcftools gtcheck - Add stats for the number of sites matched in the GT-vs-GT, GT-vs-PL, etc modes. This information is important for interpretation of the discordance score, as only the GT-vs-GT matching can be interpreted as the number of mismatching genotypes. * bcftools +mendelian2 - Fix in command line argument parsing, the `-p` and `-P` options were not functioning (#1906) * bcftools merge - New `-M, --missing-rules` option to control the behavior of merging of vector tags to prevent mixtures of known and missing values in tags when desired - Use values pertaining to the unknown allele (<*> or ) when available to prevent mixtures of known and missing values (#1888) - Revamped line matching code to fix problems in gVCF merging where split gVCF blocks would not update genotypes (#1891, #1164). * bcftool mpileup - Fix a bug in --indels-v2.0 which caused an endless loop when CIGAR operator 'H' or 'P' was encountered * bcftools norm - The `-m, --multiallelics +` mode now preserves phasing (#1893) - Symbolic alleles are now normalized too (#1919) - New `-g, --gff-annot` option to right-align indels in forward transcripts to follow HGVS 3'rule (#1929) * bcftools query - Force newline character in formatting expression when not given explicitly - Fix `-H` header output in formatting expressions containing newlines * bcftools reheader - Make `-f, --fai` aware of long contigs not representable by 32-bit integer (#1959) * bcftools +split-vep - Prevent a segfault when `-i/-e` use a VEP subfield not included in `-f` or `-c` (#1877) - New `-X, --keep-sites` option complementing the existing `-x, --drop-sites` options - Force newline character in formatting expression when not given explicitly - Fix a subtle ambiguity: identical rows must be returned when `-s` is applied regardless of `-f` containing the `-a` VEP tag itself or not. * bcftools stats - Collect new VAF (variant allele frequency) statistics from FORMAT/AD field - When counting transitions/transversions, consider also alternate het genotypes * plot-vcfstats - Add three new VAF plots ## Release 1.17 (21st February 2023) Changes affecting the whole of bcftools, or multiple commands: * The -i/-e filtering expressions - Error checks were added to prevent incorrect use of vector arithmetics. For example, when evaluating the sum of two vectors A and B, the resulting vector could contain nonsense values when the input vectors were not of the same length. The fix introduces the following logic: - evaluate to C_i = A_i + B_i when length(A)==B(A) and set length(C)=length(A) - evaluate to C_i = A_i + B_0 when length(B)=1 and set length(C)=length(A) - evaluate to C_i = A_0 + B_i when length(A)=1 and set length(C)=length(B) - throw an error when length(A)!=length(B) AND length(A)!=1 AND length(B)!=1 - Arrays in Number=R tags can be now subscripted by alleles found in FORMAT/GT. For example, FORMAT/AD[GT] > 10 .. require support of more than 10 reads for each allele FORMAT/AD[0:GT] > 10 .. same as above, but in the first sample sSUM(FORMAT/AD[GT]) > 20 .. require total sample depth bigger than 20 * The commands `consensus -H` and `+split-vep -H` - Drop unnecessary leading space in the first header column and newly print `#[1]columnName` instead of the previous `# [1]columnName` (#1856) Changes affecting specific commands: * bcftools +allele-length - Fix overflow for indels longer than 512bp and aggregate alleles equal or larger than that in the same bin (#1837) * bcftools annotate - Support sample reordering of annotation file (#1785) - Restore lost functionality of the --pair-logic option (#1808) * bcftools call - Fix a bug where too many alleles passed to `-C alleles` via `-T` caused memory corruption (#1790) - Fix a bug where indels constrained with `-C alleles -T` would sometimes be missed (#1706) * bcftools consensus - BREAKING CHANGE: the option `-I, --iupac-codes` newly outputs IUPAC codes based on FORMAT/GT of all samples. The `-s, --samples` and `-S, --samples-file` options can be used to subset samples. In order to ignore samples and consider only the REF and ALT columns (the original behavior prior to 1.17), run with `-s -` (#1828) * bcftools convert - Make variantkey conversion work for sites without an ALT allele (#1806) * bcftool csq - Fix a bug where a MNV with multiple consequences (e.g. missense + stop_gained) would report only the less severe one (#1810) - GFF file parsing was made slightly more flexible, newly ids can be just 'XXX' rather than, for example, 'gene:XXX' - New gff2gff perl script to fix GFF formatting differences * bcftools +fill-tags - More of the available annotations are now added by the `-t all` option * bcftools +fixref - New INFO/FIXREF annotation - New -m swap mode * bcftools +mendelian - The +mendelian plugin has been deprecated and replaced with +mendelian2. The function of the plugin is the same but the command line options and the output format has changed, and for this was introduced as a new plugin. * bcftools mpileup - Most of the annotations generated by mpileup are now optional via the `-a, --annotate` option and add several new (mostly experimental) annotations. - New option `--indels-2.0` for an EXPERIMENTAL indel calling model. This model aims to address some known deficiencies of the current indel calling algorithm, specifically, it uses diploid reference consensus sequence. Note that in the current version it has the potential to increase sensitivity but at the cost of decreased specificity. - Make the FS annotation (Fisher exact test strand bias) functional and remove it from the default annotations * bcftools norm - New --multi-overlaps option allows setting overlapping alleles either to the ref allele (the current default) or to a missing allele (#1764 and #1802) - Fixed a bug in `-m -` which does not split missing FORMAT values correctly and could lead to empty FORMAT fields such as `::` instead of the correct `:.:` (#1818) - The `--atomize` option previously would not split complex indels such as C>GGG. Newly these will be split into two records C>G and C>CGG (#1832) * bcftools query - Fix a rare bug where the printing of SAMPLE field with `query` was incorrectly suppressed when the `-e` option contained a sample expression while the formatting query did not. See #1783 for details. * bcftools +setGT - Add new `--new-gt X` option (#1800) - Add new `--target-gt r:FLOAT` option to randomly select a proportion of genotypes (#1850) - Fix a bug where `-t ./x` mode was advertised as selecting both phased and unphased half-missing genotypes, but was in fact selecting only unphased genotypes (#1844) * bcftools +split-vep - New options `-g, --gene-list` and `--gene-list-fields` which allow to prioritize consequences from a list of genes, or restrict output to the listed genes - New `-H, --print-header` option to print the header with `-f` - Work around a bug in the LOFTEE VEP plugin used to annotate gnomAD VCFs. There the LoF_info subfield contains commas which, in general, makes it impossible to parse the VEP subfields. The +split-vep plugin can now work with such files, replacing the offending commas with slash (/) characters. See also https://github.com/Ensembl/ensembl-vep/issues/1351 - Newly the `-c, --columns` option can be omitted when a subfield is used in `-i/-e` filtering expression. Note that `-c` may still have to be given when it is not possible to infer the type of the subfield. Note that this is an experimental feature. * bcftools stats - The per-sample stats (PSC) would not be computed when `-i/-e` filtering options and the `-s -` option were given but the expression did not include sample columns (1835) * bcftools +tag2tag - Revamp of the plugin to allow wider range of tag conversions, specifically all combinations from FORMAT/GL,PL,GP to FORMAT/GL,PL,GP,GT * bcftools +trio-dnm2 - New `-n, --strictly-novel` option to downplay alleles which violate Mendelian inheritance but are not novel - Allow to set the `--pn` and `--pns` options separately for SNVs and indels and make the indel settings more strict by default - Output missing FORMAT/VAF values in non-trio samples, rather than random nonsense values * bcftools +variant-distance - New option `-d, --direction` to choose the directionality: forward, reverse, nearest (the default) or both (#1829) ## Release 1.16 (18th August 2022) * New plugin `bcftools +variant-distance` to annotate records with distance to the nearest variant (#1690) Changes affecting the whole of bcftools, or multiple commands: * The -i/-e filtering expressions - Added support for querying of multiple filters, for example `-i 'FILTER="A;B"'` can be used to select sites with two filters "A" and "B" set. See the documentation for more examples. - Added modulo arithmetic operator Changes affecting specific commands: * bcftools annotate - A bug introduced in 1.14 caused that records with INFO/END annotation would incorrectly trigger `-c ~INFO/END` mode of comparison even when not explicitly requested, which would result in not transferring the annotation from a tab-delimited file (#1733) * bcftools merge - New `-m snp-ins-del` switch to merge SNVs, insertions and deletions separately (#1704) * bcftools mpileup - New NMBZ annotation for Mann-Whitney U-z test on number of mismatches within supporting reads - Suppress the output of MQSBZ and FS annotations in absence of alternate allele * bcftools +scatter - Fix erroneous addition of duplicate PG lines * bcftools +setGT - Custom genotypes (e.g. `-n c:1/1`) now correctly override ploidy ## Release 1.15.1 (7th April 2022) * bcftools annotate - New `-H, --header-line` convenience option to pass a header line on command line, this complements the existing `-h, --header-lines` option which requires a file with header lines * bcftools csq - A list of consequence types supported by `bcftools csq` has been added to the manual page. (#1671) * bcftools +fill-tags - Extend generalized functions so that FORMAT tags can be filled as well, for example: bcftools +fill-tags in.bcf -o out.bcf -- -t 'FORMAT/DP:1=int(smpl_sum(FORMAT/AD))' - Allow multiple custom functions in a single run. Previously the program would silently go with the last one, assigning the same values to all (#1684) * bcftools norm - Fix an assertion failure triggered when a faulty VCF file with a '-' character in the REF allele was used with `bcftools norm --atomize`. This option now checks that the REF allele only includes the allowed characters A, C, G, T and N. (#1668) - Fix the loss of phasing in half-missing genotypes in variant atomization (#1689) * bcftools roh - Fix a bug that could result in an endless loop or incorrect AF estimate when missing genotypes are present and the `--estimate-AF -` option was used (#1687) * bcftools +split-vep - VEP fields with characters disallowed in VCF tag names by the specification (such as '-' in 'M-CAP') couldn't be queried. This has been fixed, the program now sanitizes the field names, replacing invalid characters with underscore (#1686) ## Release 1.15 (21st February 2022) * New `bcftools head` subcommand for conveniently displaying the headers of a VCF or BCF file. Without any options, this is equivalent to `bcftools view --header-only --no-version` but more succinct and memorable. * The `-T, --targets-file` option had the following bug originating in HTSlib code: when an uncompressed file with multiple columns CHR,POS,REF was provided, the REF would be interpreted as 0 gigabases (#1598) Changes affecting specific commands: * bcftools annotate - In addition to `--rename-annots`, which requires a file with name mappings, it is now possible to do the same on the command line `-c NEW_TAG:=OLD_TAG` - Add new option --min-overlap to specify the minimum required overlap of intersecting regions - Allow to transfer ALT from VCF with or without replacement using bcftools annotate -a annots.vcf.gz -c ALT file.vcf.gz bcftools annotate -a annots.vcf.gz -c +ALT file.vcf.gz * bcftools convert - Revamp of `--gensample`, `--hapsample` and `--haplegendsample` family of options which includes the following changes: - New `--3N6` option to output/input the new version of the .gen file format, see https://www.cog-genomics.org/plink/2.0/formats#gen - Deprecate the `--chrom` option in favor of `--3N6`. A simple `cut` command can be used to convert from the new 3*M+6 column format to the format printed with `--chrom` (`cut -d' ' -f1,3-`). - The CHROM:POS_REF_ALT IDs which are used to detect strand swaps are required and must appear either in the "SNP ID" column or the "rsID" column. The column is autodetected for `--gensample2vcf`, can be the first or the second for `--hapsample2vcf` (depending on whether the `--vcf-ids` option is given), must be the first for `--haplegendsample2vcf`. * bcftools csq - Allow GFF files with phase column unset * bcftools filter - New `--mask`, `--mask-file` and `--mask-overlap` options to soft filter variants in regions (#1635) * bcftools +fixref - The `-m id` option now works also for non-dbSNP ids, i.e. not just `rsINT` - New `-m flip-all` mode for flipping all sites, including ambiguous A/T and C/G sites * bcftools isec - Prevent segfault on sites filtered with -i/-e in all files (#1632) * bcftools mpileup - More flexible read filtering using the options --ls, --skip-all-set .. skip reads with all of the FLAG bits set --ns, --skip-any-set .. skip reads with any of the FLAG bits set --lu, --skip-all-unset .. skip reads with all of the FLAG bits unset --nu, --skip-any-unset .. skip reads with any of the FLAG bits unset The existing synonymous options will continue to function but their use is discouraged --rf, --incl-flags STR|INT Required flags: skip reads with mask bits unset --ff, --excl-flags STR|INT Filter flags: skip reads with mask bits set * bcftools query - Make the `--samples` and `--samples-file` options work also in the `--list-samples` mode. Add a new `--force-samples` option which enables proceeding even when some of the requested samples are not present in the VCF (#1631) * bcftools +setGT - Fix a bug in `-t q -e EXPR` logic applied on FORMAT fields, sites with all samples failing the expression EXPR were incorrectly skipped. This problem affected only the use of `-e` logic, not the `-i` expressions (#1607) * bcftools sort - make use of the TMPDIR environment variable when defined * bcftools +trio-dnm2 - The --use-NAIVE mode now also adds the de novo allele in FORMAT/VA ## Release 1.14 (22nd October 2021) Changes affecting the whole of bcftools, or multiple commands: * New `--regions-overlap` and `--targets-overlap` options which address a long-standing design problem with subsetting VCF files by region. BCFtools recognize two sets of options, one for streaming (`-t/-T`) and one for index-gumping (`-r/-R`). They behave differently, the first includes only records with POS coordinate within the regions, the other includes overlapping regions. The two new options allow to modify the default behavior, see the man page for more details. * The `--output-type` option can be used to override the default compression level Changes affecting specific commands: * bcftools annotate - when `--set-id` and `--remove` are combined, `--set-id` cannot use tags deleted by `--remove`. This is now detected and the program exists with an informative error message instead of segfaulting (#1540) - while non-symbolic variation are uniquely identified by POS,REF,ALT, symbolic alleles starting at the same position were undistinguishable. This prevented correct matching of records with the same positions and variant type but different length given by INFO/END (samtools/htslib@60977f2). When annotating froma VCF/BCF, the matching is done automatically. When annotating from a tab-delimited text file, this feature can be invoked by using `-c INFO/END`. - add a new '.' modifier to control whether missing values should be carried over from a tab-delimited file or not. For example: -c TAG .. adds TAG if the source value is not missing. If TAG exists in the target file, it will be overwritten -c .TAG .. adds TAG even if the source value is missing. This can overwrite non-missing values with a missing value and can create empty VCF fields (`TAG=.`) * bcftools +check-ploidy - by default missing genotypes are not used when determining ploidy. With the new option `-m, --use-missing` it is possible to use the information carried in the missing and half-missing genotypes (e.g. ".", "./." or "./1") * bcftools concat: - new `--ligate-force` and `--ligate-warn` options for finer control of `-l, --ligate` behavior in imperfect overlaps. The new default is to throw an error when sites present in one chunk but absent in the other are encountered. To drop such sites and proceed, use the new `--ligate-warn` option (previously this was the default). To keep such sites, use the new `--ligate-force` option (#1567). * bcftools consensus: - Apply mask even when the VCF has no notion about the chromosome. It was possible to encounter this problem when `contig` lines were not present in the VCF header and no variants were called on that chromosome (#1592) * bcftools +contrast: - support for chunking within map/reduce framework allowing to collect NASSOC counts even for empty case/control sample sets (#1566) * bcftools csq: - bug fix, compound indels were not recognised in some cases (#1536) - compound variants were incorrectly marked as 'inframe' even when stop codon would occur before the frame was restored (#1551) - bug fix, FORMAT/BCSQ bitmasks could have been assigned incorrectly to some samples at multiallelic sites, a superset of the correct consequences would have been set (#1539) - bug fix, the upstream stop could be falsely assigned to all samples in a multi-sample VCF even if the stop was relevant for a single sample only (#1578) - further improve the detection of mismatching chromosome naming (e.g. "chrX" vs "X") in the GFF, VCF and fasta files * bcftools merge: - keep (sum) INFO/AN,AC values when merging VCFs with no samples (#1394) * bcftools mpileup: - new --indel-size option which allows increase of the maximum considered indel size considered, large deletions in long read data are otherwise lost. * bcftools norm: - atomization now supports Number=A,R string annotations (#1503) - assign as many alternate alleles to genotypes at multiallelic sites in the`-m +` mode, disregarding the phase. Previously the program assumed to be executed as an inverse operation of `-m -`, but when that was not the case, reference alleles would have been filled instead of multiple alternate alleles (#1542) * bcftools sort: - increase accuracy of the --max-mem option limit, previously the limit could be exceeded by more than 20% (#1576) * bcftools +trio-dnm: - new `--with-pAD` option to allow processing of VCFs without FORMAT/QS. The existing `--ppl` option was changed to the analogous `--with-pPL` * bcftools view: - the functionality of the option --compression-level lost in 1.12 has been restored ## Release 1.13 (7th July 2021) This release brings new options and significant changes in BAQ parametrization in `bcftools mpileup`. The previous behavior can be triggered by providing the `--config 1.12` option. Please see https://github.com/samtools/bcftools/pull/1474 for details. Changes affecting the whole of bcftools, or multiple commands: * Improved build system Changes affecting specific commands: * bcftools annotate: - Fix rare a bug when INFO/END is present, all INFO fields are removed with `bcftools annotate -x INFO` and BCF output is produced. Then the removed INFO/END continues to inform the end coordinate and causes incorrect retrieval of records with the -r option (#1483) - Support for matching annotation line by ID, in addition to CHROM,POS,REF, and ALT (#1461) bcftools annotate -a annots.tab.gz -c CHROM,POS,~ID,REF,ALT,INFO/END input.vcf * bcftools csq: - When GFF and VCF/fasta use a different chromosome naming convention (e.g. chrX vs X), no consequences would be added. Newly the program attempts to detect these differences and remove/add the "chr" prefix to chromosome name to match the GFF and VCF/fasta (#1507) - Parametrize brief-predictions parameter to allow explicit number of aminoacids to be printed. Note that the `-b, --brief-predictions` option is being replaced with `-B, --trim-protein-seq INT` * bcftools +fill-tags: - Generalization and better support for custom functions that allow adding new INFO tags based on arbitrary `-i, --include` type of expressions. For example, to calculate a missing INFO/DP annotation from FORMAT/AD, it is possible to use: -t 'DP:1=int(sum(FORMAT/AD))' Here the optional ":1" part specifies that a single value will be added (by default Number=. is used) and the optional int(...) adds an integer value (by default Type=Float is used). - When FORMAT/GT is not present, the INFO/AF tag will be newly calculated from INFO/AC and INFO/AN. * bcftools gtcheck: - Switch between FORMAT/GT or FORMAT/PL when one is (implicitly) requested but only the other is available - Improve diagnostics, printing warnings when a line cannot be matched and the number of lines skipped for various reasons (#1444) - Minor bug fix, with PLs being the default, the `--distinctive-sites` option started to require explicit `--error-probability 0` * bcftools index: - The program now accepts both data file name and the index file name. This adds to user convenience when running index statistics (-n, -s) * bcftools isec: - Always generate sites.txt with isec -p (#1462) * bcftools +mendelian: - Consider only complete trios, do not crash on sample name typos (#1520) * bcftools mpileup: - New `--seed` option for reproducibility of subsampling code in HTSlib - The SCR annotation which shows the number of soft-clipped reads now correctly pools reads together regardless of the variant type. Previously only reads with indels were included at indel sites. - Major revamp of BAQ. Please see https://github.com/samtools/bcftools/pull/1474 for details. The previous behavior can be triggered by providing the `--config 1.12` option. - Thanks to improvements in HTSlib, the removal of overlapping reads (which can be disabled with the `-x, --ignore-overlaps` options) is not systematically biased anymore (https://github.com/samtools/htslib/pull/1273) - Modified scale of Mann-Whitney U tests. Newly INFO/*Z annotations will be printed, for example MQBZ replaces MQB. * bcftools norm: - Fix Type=Flag output in `norm --atomize` (#1472) - Atomization must not discard ALT=. records - Atomization of AD and QS tags now correctly updates occurrences of duplicate alleles within different haplotypes - Fix a bug in atomization of Number=A,R tags * bcftools reheader: - Add `-T, --temp-prefix` option * bcftools +setGT: - A wider range of genotypes can be set by the plugin by allowing specifying custom genotypes. For example, to force a heterozygous genotype it is now possible to use expressions like: c:'m|M' c:0/1 c:0 * bcftools +split-vep: - New `-u, --allow-undef-tags` option - Better handling of ambiguous keys such as INFO/AF and CSQ/AD. The `-p, --annot-prefix` option is now applied before doing anything else which allows its use with `-f, --format` and `-c, --columns` options. - Some consequence field names may not constitute a valid tag name, such as "pos(1-based)". Newly field names are trimmed to exclude brackets. * bcftools +tag2tag: - New --QR-QA-to-QS option to convert annotations generated by Freebays to QS used by BCFtools * bcftools +trio-dnm: - Add support for sites with more than four alleles. Note that only the four most frequent alleles are considered, the model remains unchanged. Previously such sites were skipped. - New --use-NAIVE option for a naive DNM calling based solely on FORMAT/GT and expected Mendelian inheritance. This option is suitable for prefiltering. - Fix behavior to match the documentation, the `--dnm-tag DNG` option now correctly outputs log scaled values by default, not phred scaled. - Fix bug in VAF calculation, homozygous de novo variants were incorrectly reported as having VAF=50% - Fix arithmetic underflow which could lead to imprecise scores and improve sensitivity in high coverage regions - Allow combining --pn and --pns to set the noise trehsholds independently ## Release 1.12 (17th March 2021) Changes affecting the whole of bcftools, or multiple commands: * The output file type is determined from the output file name suffix, where available, so the -O/--output-type option is often no longer necessary. * Make F_MISSING in filtering expressions work for sites with multiple ALT alleles (#1343) * Fix N_PASS and F_PASS to behave according to expectation when reverse logic is used (#1397). This fix has the side effect of `query` (or programs like `+trio-stats`) behaving differently with these expressions, operating now in site-oriented rather than sample-oriented mode. For example, the new behavior could be: bcftools query -f'[%POS %SAMPLE %GT\n]' -i'N_PASS(GT="alt")==1' 11 A 0/0 11 B 0/0 11 C 1/1 while previously the same expression would return: 11 C 1/1 The original mode can be mimicked by splitting the filtering into two steps: bcftools view -i'N_PASS(GT="alt")==1' | \ bcftools query -f'[%POS %SAMPLE %GT\n]' -i'GT="alt"' Changes affecting specific commands: * bcftools annotate: - New `--rename-annots` option to help fix broken VCFs (#1335) - New -C option allows a long list of options to be read from a file to prevent very long command lines. - New `append-missing` logic allows annotations to be added for each ALT allele in the same order as they appear in the VCF. Note that this is not bullet proof. In order for this to work: - the annotation file must have one line per ALT allele - fields must contain a single value as multiple values are appended as they are and would break the correspondence between the alleles and values * bcftools concat: - Do not phase genotypes by mistake if they are not already phased with `-l` (#1346) * bcftools consensus: - New `--mask-with`, `--mark-del`, `--mark-ins`, `--mark-snv` options (#1382, #1381, #1170) - Symbolic should have only one REF base. If there are multiple, take POS+1 as the first deleted base. - Make consensus work when the first base of the reference genome is deleted. In this situation the VCF record has POS=1 and the first REF base cannot precede the event. (#1330) * bcftools +contrast: - The NOVELGT annotation was previously not added when requested. * bcftools convert: - Make the --hapsample and --hapsample2vcf options consistent with each other and with the documentation. * bcftools call: - Revamp of `call -G`, previously sample grouping by population was not truly independent and could still be influenced by the presence of other sample groups. - Optional addition of INFO/PV4 annotation with `call -a INFO/PV4` - Remove generation of useless HOB and ICB annotation; use `+fill-tags -- -t HWE,ExcHet` instead - The `call -f` option was renamed to `-a` to (1) make it consistent with `mpileup` and (2) to indicate that it includes both INFO and FORMAT annotations, not just FORMAT as previously - Any sensible Number=R,Type=Integer annotation can be used with -G, such as AD or QS - Don't trim QUAL; although usefulness of this change is questionable for true probabilistic interpretation (such high precision is unrealistic), using QUAL as a score rather than probability is helpful and permits more fine-grained filtering - Fix a suspected bug in `call -F` in the worst case, for certain improve readability - `call -C trio` is temporarily disabled * bcftools csq: - Fix a bug which caused incorrect FORMAT/BCSQ formatting at sites with too many per-sample consequences - Fix a bug which incorrectly handled the --ncsq parameter and could clash with reserved BCF values, consequently producing truncated or even incorrect output of the %TBCSQ formatting expression in `bcftools query`. To account for the reserved values, the new default value is --ncsq 15 (#1428) * bcftools +fill-tags: - MAF definition revised for multiallelic sites, the second most common allele is considered to be the minor allele (#1313) - New FORMAT/VAF, VAF1 annotations to set the fraction of alternate reads provided FORMAT/AD is present * bcftools gtcheck: - support matching of a single sample against all other samples in the file with `-s qry:sample -s gt:-`. This was previously not possible, either full cross-check mode had to be run or a list of pairs/samples had to be created explicitly * bcftools merge: - Make `merge -R` behavior consistent with other commands and pull in overlapping records with POS outside of the regions (#1374) - Bug fix (#1353) * bcftools mpileup: - Add new optional tag `mpileup -a FORMAT/QS` * bcftools norm: - New `-a, --atomize` functionality to decompose complex variants, for example MNVs into consecutive SNVs - New option `--old-rec-tag` to indicate the original variant * bcftools query: - Incorrect fields were printed in the per-sample output when subset of samples was requested via -s/-S and the order of samples in the header was different from the requested -s/-S order (#1435) * bcftools +prune: - New options --random-seed and --nsites-per-win-mode (#1050) * bcftools +split-vep: - Transcript selection now works also on the raw CSQ/BCSQ annotation. - Bug fix, samples were dropped on VCF input and VCF/BCF output (#1349) * bcftools stats: - Changes to QUAL and ts/tv plotting stats: avoid capping QUAL to predefined bins, use an open-range logarithmic binning instead - plot dual ts/tv stats: per quality bin and cumulative as if threshold applied on the whole dataset * bcftools +trio-dnm2: - Major revamp of +trio-dnm plugin, which is now deprecated and replaced by +trio-dnm2. The original trio-dnm calling model used genotype likelihoods (PLs) as the input for calling. However, that is flawed because PLs make assumptions which are unsuitable for de novo calling: PL(RR) can become bigger than PL(RA) even when the ALT allele is present in the parents. Note that this is true also for other programs such as DeNovoGear which rely on the same samtools calculation. The new recommended workflow is bcftools mpileup -a AD,QS -f ref.fa -Ou proband.bam father.bam mother.bam | bcftools call -mv -Ou | bcftools +trio-dnm -p proband,father,mother -Oz -o output.vcf.gz This new version also implements the DeNovoGear model. The original behavior of trio-dnm is no longer supported. For more details see http://samtools.github.io/bcftools/trio-dnm.pdf ## Release 1.11 (22nd September 2020) Changes affecting the whole of bcftools, or multiple commands: * Filtering -i/-e expressions - Breaking change in -i/-e expressions on the FILTER column. Originally it was possible to query only a subset of filters, but not an exact match. The new behavior is: FILTER="A" .. exact match, for example "A;B" does not pass FILTER!="A" .. exact match, for example "A;B" does pass FILTER~"A" .. both "A" and "A;B" pass FILTER!~"A" .. neither "A" nor "A;B" pass - Fix in commutative comparison operators, in some cases reversing sides would produce incorrect results (#1224; #1266) - Better support for filtering on sample subsests - Add SMPL_*/S* family of functions that evaluate within rather than across all samples. (#1180) * Improvements in the build system Changes affecting specific commands: * bcftools annotate: - Previously it was not possible to use `--columns =TAG` with INFO tags and the `--merge-logic` feature was restricted to tab files with BEG,END columns, now extended to work also with REF,ALT. - Make `annotate -TAG/+TAG` work also with FORMAT fields. (#1259) - ID and FILTER can be transferred to INFO and ID can be populated from INFO. However, the FILTER column still cannot be populated from an INFO tag because all possible FILTER values must be known at the time of writing the header (#947; #1187) * bcftools consensus: - Fix in handling symbolic deletions and overlapping variants. (#1149; #1155; #1295) - Fix `--iupac-codes` crash on REF-only positions with `ALT="."`. (#1273) - Fix `--chain` crash. (#1245) - Preserve the case of the genome reference. (#1150) - Add new `-a, --absent` option which allows setting positions with no supporting evidence to "N" (or any other character). (#848; #940) * bcftools convert: - The option `--vcf-ids` now works also with `-haplegendsample2vcf`. (#1217) - New option `--keep-duplicates` * bcftools csq: - Add `misc/gff2gff.py` script for conversion between various flavors of GFF files. The initial commit supports only one type and was contributed by @flashton2003. (#530) - Add missing consequence types. (PR #1203; #1292) - Allow overlapping CDS to support ribosomal slippage. (#1208) * bcftools +fill-tags: - Added new annotations: INFO/END, TYPE, F_MISSING. * bcftools filter: - Make `--SnpGap` optionally filter also SNPs close to other variant types. (#1126) * bcftools gtcheck: - Complete revamp of the command. The new version is faster and allows N:M sample comparisons, not just 1:N or NxN comparisons. Some functionality was lost (plotting and clustering) but may be added back on popular demand. * bcftools +mendelian: - Revamp of user options, output VCFs with mendelian errors annotation, read PED files (thanks to Giulio Genovese). * bcftools merge: - Update headers when appropriate with the '--info-rules *:join' INFO rule. (#1282) - Local alleles merging that produce LAA and LPL when requested, a draft implementation of https://github.com/samtools/hts-specs/pull/434 (#1138) - New `--no-index` which allows unindexed files to be merged. Requires the input files to have chromosomes in th same order and consistent with the order of sequences in the header. (PR #1253; samtools/htslib#1089) - Fixes in gVCF merging. (#1127; #1164) * bcftools norm: - Fixes in `--check-ref s` reference setting features with non-ACGT bases. (#473; #1300) - New `--keep-sum` switch to keep vector sum constant when splitting multiallelics. (#360) * bcftools +prune: - Extend to allow annotating with various LD metrics: r^2, Lewontin's D' (PMID:19433632), or Ragsdale's D (PMID:31697386). * bcftools query: - New `%N_PASS()` formatting expression to output the number of samples that pass the filtering expression. * bcftools reheader: - Improved error reporting to prevent user mistakes. (#1288) * bcftools roh: - Several fixes and improvements - the `--AF-file` description incorrectly suggested "REF\tALT" instead of the correct "REF,ALT". (#1142) - RG lines could have negative length. (#1144) - new `--include-noalt` option to allow also ALT=. records. (#1137) * bcftools scatter: - New plugin intended as a convenient inverse to `concat` (thanks to Giulio Genovese, PR #1249) * bcftools +split: - New `--groups-file` option for more flexibility of defining desired output. (#1240) - New `--hts-opts` option to reduce required memory by reusing one output header and allow overriding the default hFile's block size with `--hts-opts block_size=XXX`. On some file systems (lustre) the default size can be 4M which becomes a problem when splitting files with 10+ samples. - Add support for multisample output and sample renaming * bcftools +split-vep: - Add default types (Integer, Float, String) for VEP subfields and make `--columns -` extract all subfields into INFO tags in one go. ## Release 1.10.2 (19th December 2019) This is a release fix that corrects minor inconsistencies discovered in previous deliverables. ## Release 1.10 (6th December 2019) * Numerous bug fixes, usability improvements and sanity checks were added to prevent common user errors. * The -r, --regions (and -R, --regions-file) option should never create unsorted VCFs or duplicates records again. This also fixes rare cases where a spanning deletion makes a subsequent record invisible to `bcftools isec` and other commands. * Additions to filtering and formatting expressions - support for the spanning deletion alternate allele (ALT=*) - new ILEN filtering expression to be able to filter by indel length - new MEAN, MEDIAN, MODE, STDEV, phred filtering functions - new formatting expression %PBINOM (phred-scaled binomial probability), %INFO (the whole INFO column), %FORMAT (the whole FORMAT column), %END (end position of the REF allele), %END0 (0-based end position of the REF allele), %MASK (with multiple files indicates the presence of the site in other files) * New plugins - `+gvcfz`: compress gVCF file by resizing gVCF blocks according to specified criteria - `+indel-stats`: collect various indel-specific statistics - `+parental-origin`: determine parental origin of a CNV region - `+remove-overlaps`: remove overlapping variants. - `+split-vep`: query structured annotations such INFO/CSQ created by bcftools/csq or VEP - `+trio-dnm`: screen variants for possible de-novo mutations in trios * `annotate` - new -l, --merge-logic option for combining multiple overlapping regions * `call` - new `bcftools call -G, --group-samples` option which allows grouping samples into populations and applying the HWE assumption within but not across the groups. * `csq` - significant reduction of memory usage in the local -l mode for VCFs with thousands of samples and 20% reduction in the non-local haplotype-aware mode. - fixes a small memory leak and formatting issue in FORMAT/BCSQ at sites with many consequences - do not print protein sequence of start_lost events - support for "start_retained" consequence - support for symbolic insertions (ALT=""), "feature_elongation" consequence - new -b, --brief-predictions option to output abbreviated protein predictions. * `concat` - the `--naive` command now checks header compatibility when concatenating multiple files. * `consensus` - add a new `-H, --haplotype 1pIu/2pIu` feature to output first/second allele for phased genotypes and the IUPAC code for unphased genotypes - new -p, --prefix option to add a prefix to sequence names on output * `+contrast` - added support for Fisher's test probability and other annotations * `+fill-from-fasta` - new -N, --replace-non-ACGTN option * `+dosage` - fix some serious bugs in dosage calculation * `+fill-tags` - extended to perform simple on-the-fly calculations such as calculating INFO/DP from FORMAT/DP. * `merge` - add support for merging FORMAT strings - bug fixed in gVCF merging * `mpileup` - a new optional SCR annotation for the number of soft-clipped reads * `reheader` - new -f, --fai option for updating contig lines in the VCF header * `+trio-stats` - extend output to include DNM homs and recurrent DNMs * VariantKey support ## Release 1.9 (18th July 2018) * `annotate` - REF and ALT columns can be now transferred from the annotation file. - fixed bug when setting vector_end values. * `consensus` - new -M option to control output at missing genotypes - variants immediately following insersions should not be skipped. Note however, that the current fix requires normalized VCF and may still falsely skip variants adjacent to multiallelic indels. - bug fixed in -H selection handling * `convert` - the --tsv2vcf option now makes the missing genotypes diploid, "./." instead of "." - the behavior of -i/-e with --gvcf2vcf changed. Previously only sites with FILTER set to "PASS" or "." were expanded and the -i/-e options dropped sites completely. The new behavior is to let the -i/-e options control which records will be expanded. In order to drop records completely, one can stream through "bcftools view" first. * `csq` - since the real consequence of start/splice events are not known, the amino acid positions at subsequent variants should stay unchanged - add `--force` option to skip malformatted transcripts in GFFs with out-of-phase CDS exons. * `+dosage`: output all alleles and all their dosages at multiallelic sites * `+fixref`: fix serious bug in -m top conversion * `-i/-e` filtering expressions: - add two-tailed binomial test - add functions N_PASS() and F_PASS() - add support for lists of samples in filtering expressions, with many samples it was impractical to list them all on the command line. Samples can be now in a file as, e.g., GT[@samples.txt]="het" - allow multiple perl functions in the expressions and some bug fixes - fix a parsing problem, '@' was not removed from '@filename' expressions * `mpileup`: fixed bug where, if samples were renamed using the `-G` (`--read-groups`) option, some samples could be omitted from the output file. * `norm`: update INFO/END when normalizing indels * `+split`: new -S option to subset samples and to use custom file names instead of the defaults * `+smpl-stats`: new plugin * `+trio-stats`: new plugin * Fixed build problems with non-functional configure script produced on some platforms ## Release 1.8 (April 2018) * `-i, -e` filtering: Support for custom perl scripts * `+contrast`: New plugin to annotate genotype differences between groups of samples * `+fixploidy`: New options for simpler ploidy usage * `+setGT`: Target genotypes can be set to phased by giving `--new-gt p` * `run-roh.pl`: Allow to pass options directly to `bcftools roh` * Number of bug fixes ## Release 1.7 (February 2018) * `-i, -e` filtering: Major revamp, improved filtering by FORMAT fields and missing values. New GT=ref,alt,mis etc keywords, check the documentation for details. * `query`: Only matching expression are printed when both the -f and -i/-e expressions contain genotype fields. Note that this changes the original behavior. Previously all samples were output when one matching sample was found. This functionality can be achieved by pre-filtering with view and then streaming to query. Compare bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' -i'GT="alt"' file.bcf and bcftools view -i'GT="alt"' file.bcf -Ou | bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' * `annotate`: New -k, --keep-sites option * `consensus`: Fix --iupac-codes output * `csq`: Homs always considered phased and other fixes * `norm`: Make `-c none` work and remove `query -c` * `roh`: Fix errors in the RG output * `stats`: Allow IUPAC ambiguity codes in the reference file; report the number of missing genotypes * `+fill-tags`: Add ExcHet annotation * `+setGt`: Fix bug in binom.test calculation, previously it worked only for nAlt` expressions and for lists and ranges (#639) - see the man page for details. * `csq`: relax some GFF3 parsing restrictions to enable using Ensembl GFF3 files for plants (#667) * `stats`: add further documentation to output stats files (#316) and include haploid counts in per-sample output (#671). * `plot-vcfstats`: further fixes for Python3 (@nsoranzo, #645, #666). * `query` bugfix (#632) * `+setGT` plugin: new option to set genotypes based on a two-tailed binomial distribution test. Also, allow combining `-i/-e` with `-t q`. * `mpileup`: fix typo (#636) * `convert --gvcf2vcf` bugfix (#641) * `+mendelian`: recognize some mendelian inconsistencies that were being missed (@oronnavon, #660), also add support for multiallelic sites and sex chromosomes. ## Release 1.5 (June 2017) * Added autoconf support to bcftools. See `INSTALL` for more details. * `norm`: Make norm case insensitive (#601). Trim the reference allele (#602). * `mpileup`: fix for misreported indel depths for reads containing adjacent indels (3c1205c1). * `plot-vcfstats`: Open stats file in text mode, not binary (#618). * `fixref` plugin: Allow multiallelic sites in the `-i, --use-id reference`. Also flip genotypes, not just REF/ALT! * `merge`: fix gVCF merge bug when last record on a chromosome opened a gVCF block (#616) * New options added to the ROH plotting script. * `consensus`: Properly flush chain info (#606, thanks to @krooijers). * New `+prune` plugin for pruning sites by LD (R2) or maximum number of records within a window. * New N_MISSING, F_MISSING (number and fraction missing) filtering expressions. * Fix HMM initialization in `roh` when snapshots are used in multiple chromosome VCF. * Fix buffer overflow (#607) in `filter`. ## Release 1.4.1 (8 May 2017) * `roh`: Fixed malfunctioning options `-m, --genetic-map` and `-M, --rec-rate`, and newly allowed their combination. Added a convenience wrapper `misc/run-roh.pl` and an interactive script for visualizing the calls `misc/plot-roh.py`. * `csq`: More control over warning messages (#585). * Portability improvements (#587). Still work to be done on this front. * Add support for breakends to `view`, `norm`, `query` and filtering (#592). * `plot-vcfstats`: Fix for python 2/3 compatibility (#593). * New `-l, --list` option for `+af-dist` plugin. * New `-i, --use-id` option for `+fix-ref` plugin. * Add `--include/--exclude` options to `+guess-ploidy` plugin. * New `+check-sparsity` plugin. * Miscellaneous bugfixes for #575, #584, #588, #599, #535. ## Release 1.4 (13 March 2017) Two new commands - `mpileup` and `csq`: * The `mpileup` command has been imported from samtools to bcftools. The reasoning behind this is that bcftools calling is intimately tied to mpileup and any changes to one, often requires changes to the other. Only the genotype likelihood (BCF output) part of mpileup has moved to bcftools, while the textual pileup output remains in samtools. The BCF output option in `samtools mpileup` will likely be removed in a release or two or when changes to `bcftools call` are incompatible with the old mpileup output. The basic mpileup functionality remains unchanged as do most of the command line options, but there are some differences and new features that one should be aware of: - The option `samtools mpileup -t, --output-tags` changed to `bcftools mpileup -a, --annotate` to avoid conflict with the `-t, --targets` option common across other bcftools commands. - `-O, --output-BP` and `-s, --output-MQ` are no longer used as they are only for textual pipelup output, which is not included in `bcftools mpileup`. `-O` short option reassigned to `--output-type` and `-s` reassigned to `--samples` for consistency with other bcftools commands. - `-g, --BCF`, `-v, --VCF`, and ` -u, --uncompressed` options from `samtools mpileup` are no longer used, being replaced by the `-O, --output-type` option common to other bcftools commands. - The `-f, --fasta-ref` option is now required by default to help avoid user errors. Can be disabled using `--no-reference`. - The option `-d, --depth .. max per-file depth` now behaves as expected and according to the documentation, and prints a meaningful diagnostics. - The `-S, --samples-file` can be used to rename samples on the fly. See man page for details. - The `-G, --read-groups` functionality has been extended to allow reassignment, grouping and exclusion of readgroups. See man page for details. - The `-l, --positions` replaced by the `-t, --targets` and `-T, --targets-file` options to be consistent with other bcftools commands. - gVCF output is supported. Per-sample gVCFs created by mpileup can be merged using `bcftools merge --gvcf`. - Can generate mpileup output on multiple (indexed) regions using the `-r, --regions` and `-R, --regions-file` options. In samtools, one was restricted to a single region with the `-r, --region` option. - Several speedups thanks to @jkbonfield (cf3a55a). * `csq`: New command for haplotype-aware variant consequence calling. See man page and [paper](https://www.ncbi.nlm.nih.gov/pubmed/28205675). Updates, improvements and bugfixes for many other commands: * `annotate`: `--collapse` option added. `--mark-sites` now works with VCF files rather than just tab-delimited files. Now possible to annotate a subset of samples from tab file, not just VCF file (#469). Bugfixes (#428). * `call`: New option `-F, --prior-freqs` to take advantage of prior knowledge of population allele frequencies. Improved calculation of the QUAL score particularly for REF sites (#449, 7c56870). `PLs>=256` allowed in `call -m`. Bugfixes (#436). * `concat --naive` now works with vcf.gz in addition to bcf files. * `consensus`: handle variants overlapping region boundaries (#400). * `convert`: gvcf2vcf support for mpileup and GATK. new `--sex` option to assign sex to be used in certain output types (#500). Large speedup of `--hapsample` and `--haplegendsample` (e8e369b) especially with `--threads` option enabled. Bugfixes (#460). * `cnv`: improvements to output (be8b378). * `filter`: bugfixes (#406). * `gtcheck`: improved cross-check mode (#441). * `index` can now specify the path to the output index file. Also, gains the `--threads` option. * `merge`: Large overhaul of `merge` command including support for merging gVCF files created by `bcftools mpileup --gvcf` with the new `-g, --gvcf` option. New options `-F` to control filter logic and `-0` to set missing data to REF. Resolved a number of longstanding issues (#296, #361, #401, #408, #412). * `norm`: Bugfixes (#385,#452,#439), more informative error messages (#364). * `query`: `%END` plus `%POS0`, `%END0` (0-indexed) support - allows easy BED format output (#479). `%TBCSQ` for use with the new `csq` command. Bugfixes (#488,#489). * `plugin`: A number of new plugins: - `GTsubset` (thanks to @dlaehnemann) - `ad-bias` - `af-dist` - `fill-from-fasta` - `fixref` - `guess-ploidy` (deprecates `vcf2sex` plugin) - `isecGT` - `trio-switch-rate` and changes to existing plugins: - `tag2tag`: Added `gp-to-gt`, `pl-to-gl` and `--threshold` options and bugfixes (#475). - `ad-bias`: New `-d` option for minimum depth. - `impute-info`: Bugfix (49a9eaf). - `fill-tags`: Added ability to aggregate tags for sample subgroups, thanks to @mh11. (#503). HWE tag added as an option. - `mendelian`: Bugfix (#566). * `reheader`: allow muiltispace delimiters in `--samples` option. * `roh`: Now possible to process multiple samples at once. This allows considerable speedups for files with thousands of samples where the cost of HMM is negligible compared to I/O and decompressing. In order to fit tens of thousands samples in memory, a sliding HMM can be used (new `--buffer-size` option). Viterbi training now uses Baum-Welch algorithm, and works much better. Support for gVCFs or FORMAT/PL tags. Added `-o, output` and `-O, --output-type` options to control output of sites or regions (compression optional). Many bugs fixed - do not segfault on missing PL values anymore, a typo in genetic map calculation resulted in a slowdown and incorrect results. * `stats`: Bugfixes (16414e6), new options `-af-bins` and `-af-tags` to control allele frequency binning of output. Per-sample genotype concordance tables added (#477). * `view -a, --trim-alt-alleles` various bugfixes for missing data and more informative errors should now be given on failure to pinpoint problems. General changes: * Timestamps are now added to header lines summarising the command (#467). * Use of the `--threads` options should be faster across the board thanks to changes in HTSlib meaning meaning threads are now shared by the compression and decompression calls. * Changes to genotype filtering with `-i, --include` and `-e, --exclude` (#454). ## Noteworthy changes in release 1.3.1 (22 April 2016) * The `concat` command has a new `--naive` option for faster operations on large BCFs (PR #359). * `GTisec`: new plugin courtesy of David Laehnemann (@dlaehnemann) to count genotype intersections across all possible sample subsets in a VCF file. * Numerous VCF parsing fixes. * Build fix: _peakfit.c_ now builds correctly with GSL v2 (#378). * Various bug fixes and improvements to the `annotate` (#365), `call` (#366), `index` (#367), `norm` (#368, #385), `reheader` (#356), and `roh` (#328) commands, and to the `fill-tags` (#345) and `tag2tag` (#394) plugins. * Clarified documentation of `view` filter options, and of the `--regions-file` and `--targets-file` options (#357, #411). ## Noteworthy changes in release 1.3 (15 December 2016) * `bcftools call` has new options `--ploidy` and `--ploidy-file` to make handling sample ploidy easier. See man page for details. * `stats`: `-i`/`-e` short options changed to `-I`/`-E` to be consistent with the filtering `-i`/`-e` (`--include`/`--exclude`) options used in other tools. * general `--threads` option to control the number of output compression threads used when outputting compressed VCF or BCF. * `cnv` and `polysomy`: new commands for detecting CNVs, aneuploidy, and contamination from SNP genotyping data. * various new options, plugins, and bug fixes, including #84, #201, #204, #205, #208, #211, #222, #225, #242, #243, #249, #282, #285, #289, #302, #311, #318, #336, and #338. ## Noteworthy changes in release 1.2 (2 February 2016) * new `bcftools consensus` command * new `bcftools annotate` plugins: fixploidy, vcf2sex, tag2tag * more features in `bcftools convert` command, amongst others new `--hapsample` function (thanks to Warren Kretzschmar @wkretzsch) * support for complements in `bcftools annotate --remove` * support for `-i`/`-e` filtering expressions in `bcftools isec` * improved error reporting * `bcftools call` - the default prior increased from `-P 1e-3` to `-P 1.1e-3`, some clear calls were missed with default settings previously - support for the new symbolic allele `<*>` - support for `-f GQ` - bug fixes, such as: proper trimming of DPR tag with `-c`; the `-A` switch does not add back records removed by `-v` and the behaviour has been made consistent with `-c` and `-m` * many bug fixes and improvements, such as - bug in filtering, FMT & INFO vs INFO & FMT - fixes in `bcftools merge` - filter update AN/AC with `-S` - isec outputs matching records for both VCFs in the Venn mode - annotate considers alleles when working with `Number=A,R` tags - new `--set-id` feature for annotate - `convert` can be used similarly to `view` bcftools-1.21/README000066400000000000000000000042201467060157400141400ustar00rootroot00000000000000BCFtools implements utilities for variant calling (in conjunction with SAMtools) and manipulating VCF and BCF files. The program is intended to replace the Perl-based tools from vcftools. See INSTALL for building and installation instructions. Please cite this paper when using BCFtools for your publications: Twelve years of SAMtools and BCFtools Petr Danecek, James K Bonfield, Jennifer Liddle, John Marshall, Valeriu Ohan, Martin O Pollard, Andrew Whitwham, Thomas Keane, Shane A McCarthy, Robert M Davies, Heng Li GigaScience, Volume 10, Issue 2, February 2021, giab008, https://doi.org/10.1093/gigascience/giab008 @article{10.1093/gigascience/giab008, author = {Danecek, Petr and Bonfield, James K and Liddle, Jennifer and Marshall, John and Ohan, Valeriu and Pollard, Martin O and Whitwham, Andrew and Keane, Thomas and McCarthy, Shane A and Davies, Robert M and Li, Heng}, title = "{Twelve years of SAMtools and BCFtools}", journal = {GigaScience}, volume = {10}, number = {2}, year = {2021}, month = {02}, abstract = "{SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. They include tools for file format conversion and manipulation, sorting, querying, statistics, variant calling, and effect analysis amongst other methods.The first version appeared online 12 years ago and has been maintained and further developed ever since, with many new features and improvements added over the years. The SAMtools and BCFtools packages represent a unique collection of tools that have been used in numerous other software projects and countless genomic pipelines.Both SAMtools and BCFtools are freely available on GitHub under the permissive MIT licence, free for both non-commercial and commercial use. Both packages have been installed \\>1 million times via Bioconda. The source code and documentation are available from https://www.htslib.org.}", issn = {2047-217X}, doi = {10.1093/gigascience/giab008}, url = {https://doi.org/10.1093/gigascience/giab008}, note = {giab008}, eprint = {https://academic.oup.com/gigascience/article-pdf/10/2/giab008/36332246/giab008.pdf}, } bcftools-1.21/abuf.c000066400000000000000000001014251467060157400143460ustar00rootroot00000000000000/* The MIT License Copyright (c) 2021-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include "bcftools.h" #include "abuf.h" #include "rbuf.h" typedef enum { M_FIRST, M_SUM } merge_rule_t; typedef struct { kstring_t ref, alt; int ial; // the index of the original ALT allele, 1-based int beg, end; // 0-based inclusive offsets to ref,alt int plen; // the ref,alt prefix length, eg plen=1 for C>CA } atom_t; typedef struct { bcf1_t *rec; int nori, nout; // number of ALTs in the input, and VCF rows on output uint8_t *tbl; // nori columns, nout rows; indicates allele contribution to output rows, see "The atomization works as follows" below uint8_t *overlaps; // is the star allele needed for this variant? atom_t **atoms; int matoms, mtbl, moverlaps; char *info_tag; } split_t; struct _abuf_t { abuf_opt_t mode; split_t split; atom_t *atoms; int natoms, matoms; const bcf_hdr_t *hdr; bcf_hdr_t *out_hdr; bcf1_t **vcf; // dimensions stored in rbuf rbuf_t rbuf; kstring_t tmps; void *tmp, *tmp2; int32_t *gt, *tmpi; int ngt, mgt, ntmpi, mtmpi, mtmp, mtmp2; int star_allele; }; abuf_t *abuf_init(const bcf_hdr_t *hdr, abuf_opt_t mode) { if ( mode!=SPLIT ) error("todo\n"); abuf_t *buf = (abuf_t*) calloc(1,sizeof(abuf_t)); buf->hdr = hdr; buf->out_hdr = (bcf_hdr_t*) hdr; buf->mode = mode; buf->star_allele = 1; rbuf_init(&buf->rbuf, 0); return buf; } void abuf_destroy(abuf_t *buf) { int i; for (i=0; imatoms; i++) { free(buf->atoms[i].ref.s); free(buf->atoms[i].alt.s); } free(buf->atoms); free(buf->split.atoms); free(buf->split.overlaps); free(buf->split.tbl); for (i=0; irbuf.m; i++) if ( buf->vcf[i] ) bcf_destroy(buf->vcf[i]); free(buf->vcf); free(buf->gt); free(buf->tmpi); free(buf->tmp); free(buf->tmp2); free(buf->tmps.s); free(buf); } void abuf_set(abuf_t *buf, abuf_opt_t key, void *value) { if ( key==BCF_HDR ) { buf->out_hdr = *((bcf_hdr_t**)value); return; } if ( key==INFO_TAG ) { buf->split.info_tag = *((char**)value); bcf_hdr_printf(buf->out_hdr,"##INFO=",buf->split.info_tag); return; } if ( key==STAR_ALLELE ) { buf->star_allele = *((int*)value); return; } } /* Split alleles into primitivs, e.g. CC>TT becomes C>T,C>T GCGT>GTGA becomes C>T,T>A There is no sequence alignment, just trimming and hungry matching from left side. */ static void _atomize_allele(abuf_t *buf, bcf1_t *rec, int ial) { // Trim identical sequence from right char *ref = rec->d.allele[0]; char *alt = rec->d.allele[ial]; int rlen = strlen(ref); int alen = strlen(alt); while ( rlen>1 && alen>1 && ref[rlen-1]==alt[alen-1] ) rlen--, alen--; int Mlen = rlen > alen ? rlen : alen; atom_t *atom = NULL; int i; for (i=0; ialt); if ( refb!='-' ) { kputc(refb, &atom->ref); atom->end++; } continue; } buf->natoms++; hts_expand0(atom_t,buf->natoms,buf->matoms,buf->atoms); atom = &buf->atoms[buf->natoms-1]; atom->ref.l = 0; atom->alt.l = 0; kputc(refb, &atom->ref); kputc(altb, &atom->alt); atom->beg = atom->end = i; atom->ial = ial; if ( rlen!=alen && (i+1>=rlen || i+1>=alen) ) // the next base is an indel combined with SNV, e.g. C>GGG? { buf->natoms++; hts_expand0(atom_t,buf->natoms,buf->matoms,buf->atoms); atom = &buf->atoms[buf->natoms-1]; atom->ref.l = 0; atom->alt.l = 0; kputc(refb, &atom->ref); kputc(refb, &atom->alt); atom->beg = atom->end = i; atom->ial = ial; atom->plen = 1; } continue; } if ( i+1>=rlen || i+1>=alen ) // is the next base an indel? { buf->natoms++; hts_expand0(atom_t,buf->natoms,buf->matoms,buf->atoms); atom = &buf->atoms[buf->natoms-1]; atom->ref.l = 0; atom->alt.l = 0; kputc(refb, &atom->ref); kputc(altb, &atom->alt); atom->beg = atom->end = i; atom->ial = ial; } } } static int _atoms_inconsistent(const atom_t *a, const atom_t *b) { if ( a->beg < b->beg ) return -1; if ( a->beg > b->beg ) return 1; int rcmp = strcasecmp(a->ref.s,b->ref.s); if ( rcmp ) return rcmp; return strcasecmp(a->alt.s,b->alt.s); } // returns // 0 .. identical beg,ref,alt // 1 .. non-overlapping variants, but record may overlap (A>AT vs A>C) // 2 .. overlapping (conflicting) variants static int _atoms_overlap(const atom_t *a, const atom_t *b) { if ( a->beg < b->beg ) return 2; if ( a->beg > b->beg ) return 2; // consider SNV followed by DEL as not overlapping // CC > C a.plen=1 (ref,alt prefix len=1) // C > T b.plen=0 (ref,alt prefix len=0) if ( a->plen && a->plen >= b->ref.l ) return 1; if ( b->plen && b->plen >= a->ref.l ) return 1; int rcmp = strcasecmp(a->ref.s,b->ref.s); if ( rcmp ) return 2; // consider SNV followed by INS as not overlapping // A > AT a.plen=1 (ref,alt prefix len=1) // A > C b.plen=0 (ref,alt prefix len=0) if ( a->plen && a->plen >= b->alt.l ) return 1; if ( b->plen && b->plen >= a->alt.l ) return 1; rcmp = strcasecmp(a->alt.s,b->alt.s); if ( rcmp ) return 2; return 0; } /* For reproducibility of tests on different platforms, we need to guarantee the same order of identical atoms originating from different source ALTs. Even though they are consistent, different values can be picked for VCF annotations as currently the values from the one that comes first are used. */ static int _cmp_atoms(const void *aptr, const void *bptr) { const atom_t *a = (const atom_t*) aptr; const atom_t *b = (const atom_t*) bptr; int rcmp = _atoms_inconsistent(a,b); if ( rcmp ) return rcmp; if ( a->ial < b->ial ) return -1; if ( a->ial > b->ial ) return 1; return 0; } static void _split_table_init(abuf_t *buf, bcf1_t *rec, int natoms) { buf->split.rec = rec; buf->split.nori = rec->n_allele - 1; buf->split.nout = 0; hts_expand(uint8_t,buf->split.nori*natoms,buf->split.mtbl,buf->split.tbl); hts_expand(atom_t*,natoms,buf->split.matoms,buf->split.atoms); hts_expand(uint8_t,natoms,buf->split.moverlaps,buf->split.overlaps); memset(buf->split.overlaps,0,sizeof(*buf->split.overlaps)*natoms); } static void _split_table_new(abuf_t *buf, atom_t *atom) { int i, iout = buf->split.nout++; buf->split.atoms[iout] = atom; uint8_t *ptr = buf->split.tbl + iout*buf->split.nori; for (i=0; isplit.nori; i++) ptr[i] = 0; ptr[atom->ial-1] = 1; } static void _split_table_overlap(abuf_t *buf, int iout, atom_t *atom) { uint8_t *ptr = buf->split.tbl + iout*buf->split.nori; int olap = _atoms_overlap(atom,buf->split.atoms[iout]); ptr[atom->ial-1] = olap > 1 ? 2 : 1; // The test test/atomize.split.5.vcf shows why we sometimes can and sometimes // cannot remove the star allele like this // buf->split.overlaps[iout] = olap > 1 ? 1 : 0; // I forgot the details of the code, so don't immediately see // if this could be made smarter buf->split.overlaps[iout] = 1; } #if 0 static void _split_table_print(abuf_t *buf) { int i,j; for (i=0; isplit.nout; i++) { atom_t *atom = buf->split.atoms[i]; uint8_t *ptr = buf->split.tbl + i*buf->split.nori; fprintf(stderr,"%d\t%s\t%s",(int)buf->split.rec->pos+1+atom->beg,atom->ref.s,atom->alt.s); for (j=0; jsplit.nori; j++) fprintf(stderr,"\t%d",(int)ptr[j]); fprintf(stderr,"\n"); } } static void _split_table_print_atoms(abuf_t *buf) { int i; for (i=0; inatoms; i++) { atom_t *atom = &buf->atoms[i]; fprintf(stderr,"atom%d %p: ialt=%d %s>%s %d-%d\n",i,atom,atom->ial,atom->ref.s,atom->alt.s,atom->beg,atom->end); } } #endif static inline uint8_t _has_star_allele(abuf_t *buf, int iout) { if ( !buf->star_allele ) return 0; return buf->split.overlaps[iout]; } static inline int _split_table_get_ial(abuf_t *buf, int irow, int ial) { if ( !ial ) return ial; return buf->split.tbl[irow*buf->split.nori + ial - 1]; } static void _split_table_set_chrom_qual(abuf_t *buf) { int iout,j; bcf1_t *rec = buf->split.rec; for (iout=0; ioutsplit.nout; iout++) { rbuf_expand0(&buf->rbuf, bcf1_t*, buf->rbuf.n+1, buf->vcf); j = rbuf_append(&buf->rbuf); if ( !buf->vcf[j] ) buf->vcf[j] = bcf_init1(); bcf1_t *out = buf->vcf[j]; bcf_clear1(out); atom_t *atom = buf->split.atoms[iout]; out->rid = rec->rid; out->pos = rec->pos + atom->beg; bcf_update_id(buf->out_hdr, out, rec->d.id); const char *als[3]; als[0] = atom->ref.s; als[1] = atom->alt.s; als[2] = "*"; int nals = _has_star_allele(buf,iout) ? 3 : 2; bcf_update_alleles(buf->out_hdr, out, als, nals); if ( bcf_float_is_missing(rec->qual) ) bcf_float_set_missing(out->qual); else out->qual = rec->qual; bcf_update_filter(buf->out_hdr, out, rec->d.flt, rec->d.n_flt); } } int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst); static void _split_table_set_info(abuf_t *buf, bcf_info_t *info, merge_rule_t mode) { const char *tag = bcf_hdr_int2id(buf->hdr,BCF_DT_ID,info->key); int type = bcf_hdr_id2type(buf->hdr,BCF_HL_INFO,info->key); int len = bcf_hdr_id2length(buf->hdr,BCF_HL_INFO,info->key); if ( len==BCF_VL_G ) return; // todo: Number=G INFO tags if ( type==BCF_HT_LONG ) return; // todo: 64bit integers bcf1_t *rec = buf->split.rec; int mtmp = ( type==BCF_HT_INT || type==BCF_HT_REAL ) ? buf->mtmp/4 : buf->mtmp; int nval = bcf_get_info_values(buf->hdr,rec,tag,&buf->tmp,&mtmp,type); if ( type==BCF_HT_INT || type==BCF_HT_REAL ) buf->mtmp = mtmp*4; // Check for incorrect number of values. Note this check does not consider all values missing // and will remove annotations that don't pass. if ( type==BCF_HT_INT || type==BCF_HT_REAL ) { if ( (len==BCF_VL_A && nval != rec->n_allele - 1) || (len==BCF_VL_R && nval != rec->n_allele) ) return; } if ( buf->mtmp2 < buf->mtmp ) { buf->tmp2 = realloc(buf->tmp2, buf->mtmp); if ( !buf->tmp2 ) error("Failed to alloc %d bytes\n", buf->mtmp); buf->mtmp2 = buf->mtmp; } const int num_size = 4; assert( num_size==sizeof(int32_t) && num_size==sizeof(float) ); int32_t missing = bcf_int32_missing; void *missing_ptr = (void*)&missing; if ( type==BCF_HT_REAL ) bcf_float_set_missing(*((float*)missing_ptr)); int32_t vector_end = bcf_int32_vector_end; void *vector_end_ptr = (void*)&vector_end; if ( type==BCF_HT_REAL ) bcf_float_set_vector_end(*((float*)vector_end_ptr)); int iout,i; for (iout=0; ioutsplit.nout; iout++) { bcf1_t *out = buf->vcf[rbuf_kth(&buf->rbuf,iout)]; int star_allele = _has_star_allele(buf,iout); int ret = 0; if ( len==BCF_VL_FIXED || len==BCF_VL_VAR ) ret = bcf_update_info(buf->out_hdr, out, tag, type==BCF_HT_FLAG ? NULL : buf->tmp, nval, type); else if ( len==BCF_VL_A && type!=BCF_HT_STR ) { int iori = buf->split.atoms[iout]->ial - 1; assert( ioritmp+num_size*iori,num_size) ) memcpy(buf->tmp2,missing_ptr,num_size); else memcpy(buf->tmp2,buf->tmp+num_size*iori,num_size); if ( star_allele ) memcpy(buf->tmp2+num_size,missing_ptr,num_size); ret = bcf_update_info(buf->out_hdr, out, tag, buf->tmp2, 1 + star_allele, type); } else if ( len==BCF_VL_A && type==BCF_HT_STR ) { int iori = buf->split.atoms[iout]->ial - 1; kstring_t dst; dst.l = 0; dst.m = buf->mtmp2; dst.s = (char*)buf->tmp2; kputc('.',&dst); if ( star_allele ) kputs(",.",&dst); copy_string_field(buf->tmp, iori, nval, &dst, 0); if ( star_allele ) copy_string_field(".", 0, 1, &dst, 1); buf->mtmp2 = dst.m; buf->tmp2 = dst.s; ret = bcf_update_info(buf->out_hdr, out, tag, buf->tmp2, dst.l, type); } else if ( len==BCF_VL_R && type!=BCF_HT_STR ) { memcpy(buf->tmp2,buf->tmp,num_size); // REF contributes to all records int iori = buf->split.atoms[iout]->ial; assert( iorisplit.nori ); if ( !memcmp(vector_end_ptr,buf->tmp+num_size*iori,num_size) ) memcpy(buf->tmp2+num_size,missing_ptr,num_size); else memcpy(buf->tmp2+num_size,buf->tmp+num_size*iori,num_size); if ( type==BCF_HT_INT && mode==M_SUM ) { uint8_t *tbl = buf->split.tbl + iout*buf->split.nori; for (i=iori; isplit.nori; i++) { if ( tbl[i]==1 ) ((int32_t*)buf->tmp2)[1] += ((int32_t*)buf->tmp)[i+1]; } } if ( star_allele ) memcpy(buf->tmp2+2*num_size,missing_ptr,num_size); ret = bcf_update_info(buf->out_hdr, out, tag, buf->tmp2, 2 + star_allele, type); } else if ( len==BCF_VL_R && type==BCF_HT_STR ) { int iori = buf->split.atoms[iout]->ial - 1; kstring_t dst; dst.l = 0; dst.m = buf->mtmp2; dst.s = (char*)buf->tmp2; kputs(".,.",&dst); if ( star_allele ) kputs(",.",&dst); copy_string_field(buf->tmp, 0, nval, &dst, 0); copy_string_field(buf->tmp, iori+1, nval, &dst, 1); if ( star_allele ) copy_string_field(".", 0, 1, &dst, 2); buf->mtmp2 = dst.m; buf->tmp2 = dst.s; ret = bcf_update_info(buf->out_hdr, out, tag, buf->tmp2, dst.l, type); } if ( ret!=0 ) error("An error occurred while updating INFO/%s (errcode=%d)\n",tag,ret); } } static void _split_table_set_history(abuf_t *buf) { int i,j,ret; bcf1_t *rec = buf->split.rec; // Don't update if the tag already exists. This is to prevent -a from overwriting -m int m = 0; char *tmp = NULL; ret = bcf_get_info_string(buf->hdr,rec,buf->split.info_tag,&tmp,&m); free(tmp); if ( ret>0 ) return; buf->tmps.l = 0; ksprintf(&buf->tmps,"%s|%"PRIhts_pos"|%s|",bcf_seqname(buf->hdr,rec),rec->pos+1,rec->d.allele[0]); for (i=1; in_allele; i++) { kputs(rec->d.allele[i],&buf->tmps); if ( i+1n_allele ) kputc(',',&buf->tmps); else kputc(',',&buf->tmps); } int len = buf->tmps.l; buf->tmps.s[buf->tmps.l-1] = '|'; for (i=0; isplit.nout; i++) { buf->tmps.l = len; bcf1_t *out = buf->vcf[rbuf_kth(&buf->rbuf,i)]; uint8_t *ptr = buf->split.tbl + i*buf->split.nori; for (j=0; jsplit.nori; j++) { if ( ptr[j]!=1 ) continue; kputw(j+1,&buf->tmps); kputc(',',&buf->tmps); } buf->tmps.s[--buf->tmps.l] = 0; if ( (ret=bcf_update_info_string(buf->out_hdr, out, buf->split.info_tag, buf->tmps.s))!=0 ) error("An error occurred while updating INFO/%s (errcode=%d)\n",buf->split.info_tag,ret); } } static void _split_table_set_gt(abuf_t *buf) { int nsmpl = bcf_hdr_nsamples(buf->hdr); if ( !nsmpl ) return; bcf1_t *rec = buf->split.rec; buf->ngt = bcf_get_genotypes(buf->hdr, rec, &buf->gt, &buf->mgt); if ( buf->ngt<=0 ) return; else hts_expand(int32_t,buf->ngt,buf->mtmpi,buf->tmpi); int iout,i,j; for (iout=0; ioutsplit.nout; iout++) { bcf1_t *out = buf->vcf[rbuf_kth(&buf->rbuf,iout)]; int star_allele = _has_star_allele(buf,iout); int max_ploidy = buf->ngt/nsmpl; int32_t *src = buf->gt, *dst = buf->tmpi; for (i=0; i=rec->n_allele ) error("Out-of-bounds genotypes at %s:%"PRIhts_pos"\n",bcf_seqname(buf->hdr,rec),rec->pos+1); int ial = _split_table_get_ial(buf,iout,iori); if ( ial==2 && !star_allele ) { dst[j] = bcf_gt_missing; if ( bcf_gt_is_phased(src[j]) ) dst[j] |= 1; } else dst[j] = bcf_gt_is_phased(src[j]) ? bcf_gt_phased(ial) : bcf_gt_unphased(ial); } src += max_ploidy; dst += max_ploidy; } bcf_update_genotypes(buf->out_hdr,out,buf->tmpi,buf->ngt); } } static void _split_table_set_format(abuf_t *buf, bcf_fmt_t *fmt, merge_rule_t mode) { int nsmpl = bcf_hdr_nsamples(buf->hdr); if ( !nsmpl ) return; const char *tag = bcf_hdr_int2id(buf->hdr,BCF_DT_ID,fmt->id); if ( tag[0]=='G' && tag[1]=='T' && !tag[2] ) // FORMAT/GT { _split_table_set_gt(buf); return; } int type = bcf_hdr_id2type(buf->hdr,BCF_HL_FMT,fmt->id); int len = bcf_hdr_id2length(buf->hdr,BCF_HL_FMT,fmt->id); if ( type==BCF_HT_STR && len==BCF_VL_G ) return; // possible todo: Number=G for strings if ( type==BCF_HT_LONG ) return; // todo: 64bit integers const int num_size = 4; assert( num_size==sizeof(int32_t) && num_size==sizeof(float) ); int32_t missing = bcf_int32_missing; void *missing_ptr = (void*)&missing; if ( type==BCF_HT_REAL ) bcf_float_set_missing(*((float*)missing_ptr)); int32_t vector_end = bcf_int32_vector_end; void *vector_end_ptr = (void*)&vector_end; if ( type==BCF_HT_REAL ) bcf_float_set_vector_end(*((float*)vector_end_ptr)); bcf1_t *rec = buf->split.rec; int mtmp = ( type==BCF_HT_INT || type==BCF_HT_REAL ) ? buf->mtmp/num_size : buf->mtmp; // number of items int nval = bcf_get_format_values(buf->hdr,rec,tag,&buf->tmp,&mtmp,type); if ( type==BCF_HT_INT || type==BCF_HT_REAL ) buf->mtmp = mtmp*num_size; // number of bytes if ( type==BCF_HT_INT || type==BCF_HT_REAL ) { if ( len==BCF_VL_G && nval!=nsmpl*rec->n_allele && nval!=nsmpl*rec->n_allele*(rec->n_allele+1)/2 ) return; // not haploid nor diploid // Check for incorrect number of values. Note this check does not consider all values missing // and will remove annotations that don't pass. if ( (len==BCF_VL_A && nval != nsmpl*(rec->n_allele - 1)) || (len==BCF_VL_R && nval != nsmpl*rec->n_allele) ) return; } // Increase buffer size to accommodate star allele int nval1 = nval / nsmpl; mtmp = buf->mtmp; if ( type==BCF_HT_INT || type==BCF_HT_REAL ) { if ( (len==BCF_VL_A || len==BCF_VL_R) && mtmp < num_size*nsmpl*(nval1+1) ) mtmp = num_size*nsmpl*(nval1+1); // +1 for the possibility of the star allele else if ( len==BCF_VL_G && mtmp < num_size*nsmpl*(nval1+3) ) mtmp = num_size*nsmpl*(nval1+3); } else if ( type==BCF_HT_STR ) { if ( (len==BCF_VL_A || len==BCF_VL_R) && mtmp < nsmpl*(nval1+2) ) mtmp = nsmpl*(nval1+2); // +2 for the possibility of the star allele, ",." else if ( len==BCF_VL_G && mtmp < nsmpl*(nval1+6) ) mtmp = nsmpl*(nval1+6); } if ( buf->mtmp2 < mtmp ) { buf->tmp2 = realloc(buf->tmp2, mtmp); if ( !buf->tmp2 ) error("Failed to alloc %d bytes\n", mtmp); buf->mtmp2 = mtmp; } int iout, i, j; for (iout=0; ioutsplit.nout; iout++) { int star_allele = _has_star_allele(buf,iout); bcf1_t *out = buf->vcf[rbuf_kth(&buf->rbuf,iout)]; int ret = 0; if ( len==BCF_VL_FIXED || len==BCF_VL_VAR ) ret = bcf_update_format(buf->out_hdr, out, tag, buf->tmp, nval, type); else if ( len==BCF_VL_A && type!=BCF_HT_STR ) { int iori = buf->split.atoms[iout]->ial - 1; assert( ioritmp + nval1*num_size*i; void *dst = buf->tmp2 + num_size*i*(star_allele+1); if ( !memcmp(vector_end_ptr,src+iori*num_size,num_size) ) memcpy(dst,missing_ptr,num_size); else memcpy(dst,src+iori*num_size,num_size); if ( star_allele ) memcpy(dst+num_size,missing_ptr,num_size); } ret = bcf_update_format(buf->out_hdr, out, tag, buf->tmp2, nsmpl*(star_allele+1), type); } else if ( (len==BCF_VL_A || len==BCF_VL_R) && type==BCF_HT_STR ) { int ioff = len==BCF_VL_R ? 1 : 0; int iori = buf->split.atoms[iout]->ial - 1; int nval1_dst = star_allele ? nval1 + 2 : nval1; memset(buf->tmp2,0,nval1_dst*nsmpl); for (i=0; itmp2 + nval1_dst*i; kputc_('.',&dst); if ( star_allele ) kputsn_(",.",2,&dst); if ( len==BCF_VL_R ) { kputsn_(",.",2,&dst); copy_string_field(buf->tmp+nval1*i, 0, nval1, &dst, 0); } copy_string_field(buf->tmp+nval1*i, iori+ioff, nval1, &dst, 0+ioff); if ( star_allele ) copy_string_field(".", 0, 1, &dst, 1+ioff); } ret = bcf_update_format(buf->out_hdr, out, tag, buf->tmp2, nval1_dst*nsmpl, type); } else if ( len==BCF_VL_R && type!=BCF_HT_STR ) { int iori = buf->split.atoms[iout]->ial; assert( iori<=nval ); for (i=0; itmp + nval1*num_size*i; void *dst = buf->tmp2 + num_size*i*(star_allele+2); memcpy(dst,src,num_size); memcpy(dst+num_size,src+iori*num_size,num_size); if ( type==BCF_HT_INT && mode==M_SUM ) { uint8_t *tbl = buf->split.tbl + iout*buf->split.nori; for (j=iori; jsplit.nori; j++) if ( tbl[j]==1 ) ((int32_t*)dst)[1] += ((int32_t*)src)[j+1]; } if ( star_allele ) memcpy(dst+num_size*2,missing_ptr,num_size); } ret = bcf_update_format(buf->out_hdr, out, tag, buf->tmp2, nsmpl*(star_allele+2), type); } else if ( len==BCF_VL_G && type!=BCF_HT_STR ) { int iori = buf->split.atoms[iout]->ial; int i01 = bcf_alleles2gt(0,iori); int i11 = bcf_alleles2gt(iori,iori); assert( ioritmp + i*nval1; \ type_t *dst = (type_t*)buf->tmp2 + i*3*(1+star_allele); \ int n=0; /* determine ploidy of this genotype */ \ while ( ntmp + i*nval1; \ memcpy(dst++,src,sizeof(type)); \ int nmiss = 0, nend = 0; \ if ( n==rec->n_allele ) /* haploid */ \ { \ memcpy(dst++,src+iori,sizeof(type)); \ if ( star_allele ) { nmiss = 1; nend = 3; } \ else nend = 1; \ } \ else if ( n==nval1 ) \ { \ memcpy(dst++,src+i01,sizeof(type)); \ memcpy(dst++,src+i11,sizeof(type)); \ if ( star_allele ) nmiss = 3; \ } \ else if ( n==1 && is_missing ) \ { \ if ( star_allele ) nend = 5; \ else nend = 2; \ } \ else \ error("Incorrect number of values at %s:%"PRIhts_pos" .. tag=FORMAT/%s Number=G nAlleles=%d nValues=%d, %d-th sample\n", \ bcf_seqname(buf->hdr,rec),rec->pos+1,tag,rec->n_allele,n,i+1); \ for (j=0; jout_hdr, out, tag, buf->tmp2, 3*(1+star_allele)*nsmpl, type); } if ( ret!=0 ) error("An error occurred while updating FORMAT/%s (errcode=%d)\n",tag,ret); } } static inline int _is_acgtn(char *seq) { while ( *seq ) { char c = toupper(*seq); if ( c!='A' && c!='C' && c!='G' && c!='T' && c!='N' ) return 0; seq++; } return 1; } /* The atomization works as follows: - Atomize each alternate allele separately by leaving out sequence identical to the reference. No alignment is performed, just greedy trimming of the end, then from left. This operation returns a list of atoms (atom_t) which carry fragments of REF,ALT and their positions as 0-based offsets to the original REF allele - Sort atoms by POS, REF and ALT. Each unique atom (POS+REF+ALT) forms a new VCF record, each with a single ALT. - For each new VCF record determine how to translate the original allele index (iori) to this new record: - 1: the original allele matches the atom - 0: the original allele does not overlap this atom or the overlapping part matches the REF allele - 2 (or equivalently "."): there is a mismatch between the original allele and the atom The mapping is encoded in a table with columns corresponding to the original ALTs and rows to the new POS+ALTs (atoms). The table is initialized to 0, then we set 1's for matching atoms and 2's for overlapping mismatching atoms. Note that different ALT alleles can result in the same atom (the same output line) and this code does not know how to reconcile possibly conflicting VCF annotations. This could be improved and merge logic provided, similarly to `merge -l`. For example, the allelic depths (AD) should be summed for the same atomized output allele. However, this level of complexity is not addressed in this initial draft. Higher priority for now is to provide the inverse "join" operation. Update 2021-04-09: Tags QS,AD are now automatically incremented as they should be, for both INFO and FORMAT. Note that the code will fail on missing values (todo) and it needs to be generalized and made customizable. */ void _abuf_split(abuf_t *buf, bcf1_t *rec) { int i,j; if ( rec->n_allele < 2 ) { rbuf_expand0(&buf->rbuf, bcf1_t*, buf->rbuf.n+1, buf->vcf); int j = rbuf_append(&buf->rbuf); if ( buf->vcf[j] ) bcf_destroy(buf->vcf[j]); buf->vcf[j] = bcf_dup(rec); return; } for (i=0; in_allele; i++) { if ( _is_acgtn(rec->d.allele[i]) ) continue; rbuf_expand0(&buf->rbuf, bcf1_t*, buf->rbuf.n+1, buf->vcf); int j = rbuf_append(&buf->rbuf); if ( buf->vcf[j] ) bcf_destroy(buf->vcf[j]); buf->vcf[j] = bcf_dup(rec); return; } buf->natoms = 0; for (i=1; in_allele; i++) _atomize_allele(buf,rec,i); qsort(buf->atoms,buf->natoms,sizeof(*buf->atoms),_cmp_atoms); _split_table_init(buf,rec,buf->natoms); for (i=0; inatoms; i++) { if ( i && _atoms_inconsistent(&buf->atoms[i-1],&buf->atoms[i])==0 ) continue; _split_table_new(buf, &buf->atoms[i]); // add a new unique output atom } for (i=0; inatoms; i++) { // Looping over sorted list of all atoms with possible duplicates from different source ALT alleles atom_t *atom = &buf->atoms[i]; for (j=0; jsplit.nout; j++) { atom_t *out = buf->split.atoms[j]; if ( atom == out ) continue; // table already set to 1 if ( atom->beg > out->end ) continue; // cannot overlap this output atom if ( atom->end < out->beg ) break; // this atom is ahead of all subsequent output records _split_table_overlap(buf, j, atom); } } // _split_table_print(buf); // _split_table_print_atoms(buf); assert( !buf->rbuf.n ); // all records should be flushed first in the SPLIT mode // Create the output records, transferring all annotations: // CHROM-QUAL _split_table_set_chrom_qual(buf); // INFO for (i=0; in_info; i++) { // this implementation of merging rules is temporary: generalize and made customizable through the API merge_rule_t mode = M_FIRST; const char *tag = bcf_hdr_int2id(buf->hdr,BCF_DT_ID,rec->d.info[i].key); if ( !strcmp(tag,"QS") || !strcmp(tag,"AD") ) mode = M_SUM; _split_table_set_info(buf, &rec->d.info[i], mode); } // Set INFO tag showing the original record if ( buf->split.info_tag ) _split_table_set_history(buf); // FORMAT for (i=0; in_fmt; i++) { // this implementation of merging rules is temporary: generalize and made customizable through the API merge_rule_t mode = M_FIRST; const char *tag = bcf_hdr_int2id(buf->hdr,BCF_DT_ID,rec->d.fmt[i].id); if ( !strcmp(tag,"QS") || !strcmp(tag,"AD") ) mode = M_SUM; _split_table_set_format(buf, &rec->d.fmt[i], mode); } // Check that at least one FORMAT field was added, if not, the number of samples must be set manually for (i=0; isplit.nout; i++) { bcf1_t *out = buf->vcf[rbuf_kth(&buf->rbuf,i)]; if ( !out->n_sample ) out->n_sample = rec->n_sample; } } void abuf_push(abuf_t *buf, bcf1_t *rec) { bcf_unpack(rec, BCF_UN_ALL); if ( buf->mode==SPLIT ) _abuf_split(buf,rec); } bcf1_t *abuf_flush(abuf_t *buf, int flush_all) { int i; if ( buf->rbuf.n==0 ) return NULL; if ( flush_all ) goto ret; ret: i = rbuf_shift(&buf->rbuf); return buf->vcf[i]; } bcftools-1.21/abuf.h000066400000000000000000000047311467060157400143550ustar00rootroot00000000000000/* The MIT License Copyright (c) 2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Atomize/deatomize complex variants */ #ifndef __ABUF_H__ #define __ABUF_H__ #include typedef struct _abuf_t abuf_t; // Modes of operation typedef enum { NONE, // mode of operation, to be passed to abuf_init SPLIT, JOIN, BCF_HDR, // should the records be annotated, a writable bcf header is required INFO_TAG, // set BCF_HDR first STAR_ALLELE // 1: use STAR allele (the default), 0: set overlaps to missing } abuf_opt_t; #define abuf_set_opt(buf,type,key,value) { type tmp = value; abuf_set(buf, key, (void*)&tmp); } void abuf_set(abuf_t *buf, abuf_opt_t key, void *value); /* * abuf_init() - init buffer * @win: number of sites (>0) or bp (<0) */ abuf_t *abuf_init(const bcf_hdr_t *hdr, abuf_opt_t mode); void abuf_destroy(abuf_t *buf); /* * abuf_push() - Push a new site for analysis */ void abuf_push(abuf_t *buf, bcf1_t *rec); /* * abuf_flush() - Return next buffered record * @flush_all: Set to 1 if no more overlapping records are coming (e.g. end of chromosome or end of file), * the buffer can be emptied. * return: The next atomized/deatomized VCF record or NULL if no record is ready. The returned * structure will be cleaned by abuf. */ bcf1_t *abuf_flush(abuf_t *buf, int flush_all); #endif bcftools-1.21/bam2bcf.c000066400000000000000000001444611467060157400147340ustar00rootroot00000000000000/* bam2bcf.c -- variant calling. Copyright (C) 2010-2012 Broad Institute. Copyright (C) 2012-2024 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include "bam2bcf.h" extern void ks_introsort_uint32_t(size_t n, uint32_t a[]); #define CALL_DEFTHETA 0.83 #define DEF_MAPQ 20 #define CAP_DIST 25 bcf_callaux_t *bcf_call_init(double theta, int min_baseQ, int max_baseQ, int delta_baseQ) { bcf_callaux_t *bca; if (theta <= 0.) theta = CALL_DEFTHETA; bca = (bcf_callaux_t*) calloc(1, sizeof(bcf_callaux_t)); bca->capQ = 60; bca->openQ = 40; bca->extQ = 20; bca->tandemQ = 100; bca->min_baseQ = min_baseQ; bca->max_baseQ = max_baseQ; bca->delta_baseQ = delta_baseQ; bca->e = errmod_init(1. - theta); bca->min_frac = 0.002; bca->min_support = 1; bca->per_sample_flt = 0; bca->npos = 100; bca->ref_pos = (int*) malloc(bca->npos*sizeof(int)); bca->alt_pos = (int*) malloc(bca->npos*sizeof(int)); bca->iref_pos= (int*) malloc(bca->npos*sizeof(int)); bca->ialt_pos= (int*) malloc(bca->npos*sizeof(int)); bca->nqual = 60; bca->ref_mq = (int*) malloc(bca->nqual*sizeof(int)); bca->alt_mq = (int*) malloc(bca->nqual*sizeof(int)); bca->iref_mq = (int*) malloc(bca->nqual*sizeof(int)); bca->ialt_mq = (int*) malloc(bca->nqual*sizeof(int)); bca->ref_bq = (int*) malloc(bca->nqual*sizeof(int)); bca->alt_bq = (int*) malloc(bca->nqual*sizeof(int)); bca->fwd_mqs = (int*) malloc(bca->nqual*sizeof(int)); bca->rev_mqs = (int*) malloc(bca->nqual*sizeof(int)); return bca; } void bcf_iaux_destroy(bcf_callaux_t *bca); void bcf_call_destroy(bcf_callaux_t *bca) { if (bca == 0) return; bcf_iaux_destroy(bca); errmod_destroy(bca->e); if (bca->npos) { free(bca->ref_pos); free(bca->alt_pos); free(bca->iref_pos); free(bca->ialt_pos); bca->npos = 0; } free(bca->ref_mq); free(bca->alt_mq); free(bca->iref_mq); free(bca->ialt_mq); free(bca->ref_bq); free(bca->alt_bq); free(bca->fwd_mqs); free(bca->rev_mqs); bca->nqual = 0; free(bca->bases); free(bca->inscns); free(bca); } static int get_aux_nm(const bam_pileup1_t *p, int32_t qpos, int is_ref) { int64_t nm; const bam_pileup_cd *cd = &p->cd; if ( PLP_NM(cd) == -1 ) return -1; if ( PLP_NM(cd) == PLP_NM_UNSET ) { // todo: make this localized to be useful for long reads as well bam1_t *rec = p->b; uint8_t *nm_tag = bam_aux_get(rec, "NM"); if ( !nm_tag ) { PLP_NM(cd) = -1; return -1; } nm = bam_aux2i(nm_tag); // Count indels as single events, not as the number of inserted/deleted // bases (which is what NM does). Add soft clips as mismatches. int i; for (i=0; i < rec->core.n_cigar; i++) { int val = bam_get_cigar(rec)[i] & BAM_CIGAR_MASK; if ( val==BAM_CSOFT_CLIP ) { nm += bam_get_cigar(rec)[i] >> BAM_CIGAR_SHIFT; } else if ( val==BAM_CINS || val==BAM_CDEL ) { val = bam_get_cigar(rec)[i] >> BAM_CIGAR_SHIFT; if ( val > 1 ) nm -= val - 1; } } PLP_NM(cd) = nm; } else nm = PLP_NM(cd); // Take into account MNPs, 2% of de novo SNVs appear within 20bp of another de novo SNV // http://www.genome.org/cgi/doi/10.1101/gr.239756.118 nm -= is_ref ? 1 : 2; if ( nm < 0 ) nm = 0; if ( nm >= B2B_N_NM ) nm = B2B_N_NM - 1; return nm; } // position in the sequence with respect to the aligned part of the read static int get_position(const bam_pileup1_t *p, int *len, int *sc_len, int *sc_dist) { int i, j, edist = p->qpos + 1; int sc_left = 0, sc_right = 0; int sc_left_dist = -1, sc_right_dist = -1; // left end for (i = 0; i < p->b->core.n_cigar; i++) { int cig = bam_get_cigar(p->b)[i] & BAM_CIGAR_MASK; if (cig == BAM_CHARD_CLIP) continue; else if (cig == BAM_CSOFT_CLIP) sc_left += bam_get_cigar(p->b)[i] >> BAM_CIGAR_SHIFT; else break; } if (sc_left) sc_left_dist = p->qpos+1 - sc_left; edist -= sc_left; // right end for (j = p->b->core.n_cigar-1; j >= i; j--) { int cig = bam_get_cigar(p->b)[j] & BAM_CIGAR_MASK; if (cig == BAM_CHARD_CLIP) continue; else if (cig == BAM_CSOFT_CLIP) sc_right += bam_get_cigar(p->b)[j] >> BAM_CIGAR_SHIFT; else break; } if (sc_right) sc_right_dist = p->b->core.l_qseq - sc_right - p->qpos; // Distance to nearest soft-clips and length of that clip. if (sc_left_dist >= 0) { if (sc_right_dist < 0 || sc_left_dist < sc_right_dist) { *sc_len = sc_left; *sc_dist = sc_left_dist; } } else if (sc_right_dist >= 0) { *sc_len = sc_right; *sc_dist = sc_right_dist; } else { *sc_len = 0; *sc_dist = 0; } *len = p->b->core.l_qseq - sc_left - sc_right; return edist; } void bcf_callaux_clean(bcf_callaux_t *bca, bcf_call_t *call) { memset(bca->ref_pos,0,sizeof(int)*bca->npos); memset(bca->alt_pos,0,sizeof(int)*bca->npos); memset(bca->iref_pos,0,sizeof(int)*bca->npos); memset(bca->ialt_pos,0,sizeof(int)*bca->npos); memset(bca->ref_mq,0,sizeof(int)*bca->nqual); memset(bca->alt_mq,0,sizeof(int)*bca->nqual); memset(bca->iref_mq,0,sizeof(int)*bca->nqual); memset(bca->ialt_mq,0,sizeof(int)*bca->nqual); memset(bca->ref_bq,0,sizeof(int)*bca->nqual); memset(bca->alt_bq,0,sizeof(int)*bca->nqual); memset(bca->fwd_mqs,0,sizeof(int)*bca->nqual); memset(bca->rev_mqs,0,sizeof(int)*bca->nqual); if ( call->ADF ) memset(call->ADF,0,sizeof(int32_t)*(call->n+1)*B2B_MAX_ALLELES); if ( call->ADR ) memset(call->ADR,0,sizeof(int32_t)*(call->n+1)*B2B_MAX_ALLELES); if ( call->SCR ) memset(call->SCR,0,sizeof(*call->SCR)*(call->n+1)); if ( call->SCR ) memset(call->SCR,0,sizeof(*call->SCR)*(call->n+1)); if ( bca->fmt_flag&B2B_FMT_NMBZ ) { memset(call->ref_nm,0,sizeof(*call->ref_nm)*(call->n+1)*B2B_N_NM); memset(call->alt_nm,0,sizeof(*call->alt_nm)*(call->n+1)*B2B_N_NM); } else { memset(call->ref_nm,0,sizeof(*call->ref_nm)*B2B_N_NM); memset(call->alt_nm,0,sizeof(*call->alt_nm)*B2B_N_NM); } memset(call->QS,0,sizeof(*call->QS)*call->n*B2B_MAX_ALLELES); memset(bca->ref_scl, 0, 100*sizeof(int)); memset(bca->alt_scl, 0, 100*sizeof(int)); memset(bca->iref_scl, 0, 100*sizeof(int)); memset(bca->ialt_scl, 0, 100*sizeof(int)); int i; for (i=0; i<2; i++) bca->nnm[i] = 0; for (i=0; i<2; i++) bca->nm[i] = 0; } /* Notes: - Called from bam_plcmd.c by mpileup. Amongst other things, sets the bcf_callret1_t.QS frequencies which are carried over via bcf_call_combine and bcf_call2bcf to the output BCF as the INFO/QS and FMT/QS annotations. Later it's used for multiallelic calling by `call -m`, `call -mG` and `+trio-dnm`. - ref_base is the 4-bit representation of the reference base. It is negative if we are looking at an indel. */ /* * This function is called once for each sample. * _n is number of pilesups pl contributing reads to this sample * pl is pointer to array of _n pileups (one pileup per read) * ref_base is the 4-bit representation of the reference base. It is negative if we are looking at an indel. * bca is the settings to perform calls across all samples * r is the returned value of the call */ int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r) { int i, n, ref4, is_indel, ori_depth = 0; #ifdef GLF_DEBUG fprintf(stderr, "Call GLFGEN\n"); #endif // clean from previous run r->ori_depth = 0; r->mq0 = 0; memset(r->anno,0,sizeof(double)*16); memset(r->p,0,sizeof(float)*25); r->SCR = 0; if (ref_base >= 0) { ref4 = seq_nt16_int[ref_base]; is_indel = 0; } else ref4 = 4, is_indel = 1; if (_n == 0) return -1; // enlarge the bases array if necessary if (bca->max_bases < _n) { bca->max_bases = _n; kroundup32(bca->max_bases); bca->bases = (uint16_t*)realloc(bca->bases, 2 * bca->max_bases); } // Detect if indel occurs anywhere in this sample int indel_in_sample = 0; if (bca->edlib) { for (i = n = 0; i < _n; ++i) { const bam_pileup1_t *p = pl + i; if (p->indel) indel_in_sample = 1; } } // fill the bases array double nqual_over_60 = bca->nqual / 60.0; int ADR_ref_missed[4] = {0}; int ADF_ref_missed[4] = {0}; for (i = n = 0; i < _n; ++i) { const bam_pileup1_t *p = pl + i; int b; // the base or indel type int q; // the base or indel quality used to calculate PL int seqQ; // used to cap the indel quality given the sequence context int mapQ; // to cap the quality for low MQ reads int baseQ; // used only for supporting INFO annotations int is_diff; // is this base or indel type different from the reference int min_dist; // distance from the end, used for tail distance bias if ( bca->fmt_flag&(B2B_INFO_SCR|B2B_FMT_SCR) && PLP_HAS_SOFT_CLIP(&p->cd) ) r->SCR++; if (p->is_refskip || (p->b->core.flag&BAM_FUNMAP)) continue; // The meaning of the indel related variables: // is_indel .. is this position currently tested for an indel // p->is_del .. is the current base a deletion in this read (unrelated to the tested indel) // p->indel .. is there an indel starting after this position (i.e. does this read have the tested indel) if (p->is_del && !is_indel) continue; // not testing an indel and the read has a spanning deletion int inm = -1; ++ori_depth; if (is_indel) // testing an indel position { b = p->aux>>16&0x3f; // indel type seqQ = q = (p->aux & 0xff); // mp2 + builtin indel-bias if (bca->edlib) { if (indel_in_sample) { seqQ = q = (p->aux & 0xff); // mp2 + builtin indel-bias } else if (p->aux & 0xff) { // An indel in another sample, but not this. So just use // basic sequence confidences. q = bam_get_qual(p->b)[p->qpos]; if (q > bca->max_baseQ) q = bca->max_baseQ; seqQ = 99; } } if ( !bca->indels_v20 && !bca->edlib ) { /* This heuristics was introduced by e4e161068 and claims to fix #1446. However, we obtain correct result on the provided test case even when this code is commented out, so this may not be needed anymore. Leaving it in only for backward compatibility for now. See mpileup-tests homdel-issue-1446 and CHM1_CHM13_2.45x-1-1701408 which work only when this code is disabled. */ if (p->indel == 0 && (q < _n/2 || _n > 20)) { // high quality indel calls without p->indel set aren't // particularly indicative of being a good REF match either, // at least not in low coverage. So require solid coverage // before we start utilising such quals. b = 0; q = (int)bam_get_qual(p->b)[p->qpos]; seqQ = (3*seqQ + 2*q)/8; } if (_n > 20 && seqQ > 40) seqQ = 40; } is_diff = b ? 1 : 0; if ( bca->fmt_flag&(B2B_FMT_NMBZ|B2B_INFO_NMBZ|B2B_INFO_NM) ) { inm = get_aux_nm(p,p->qpos,is_diff?0:1); if ( inm>=0 ) { bca->nnm[is_diff]++; bca->nm[is_diff] += inm; } } #ifdef GLF_DEBUG fprintf(stderr, "GLF %s\t%d\t%d\n", bam_get_qname(p->b), bca->indel_types[b], q); #endif if (q < bca->min_baseQ) { if (!p->indel && b < 4) // not an indel read { if (bam_is_rev(p->b)) ADR_ref_missed[b]++; else ADF_ref_missed[b]++; } continue; } #ifndef MIN #define MIN(a,b) ((a)<(b)?(a):(b)) #endif #ifndef MAX #define MAX(a,b) ((a)>(b)?(a):(b)) #endif #if 1 // TEST 6 if (bca->edlib) { // Deeper data should rely more heavily on counts of data // than quality, as quality can be unreliable and prone to // miscalculations through BAQ, STR analysis, etc. // So we put a cap on how good seqQ can be. // // Is it simply the equivalent of increasing -F filter? // Not quite, as the latter removes many real variants upfront. // This calls them and then post-adjusts quality, potentially // dropping it later or changing genotype. So we still get // calls, but lower qual. seqQ = MIN(seqQ, bca->seqQ_offset-(MIN(20,_n)*5)); if (indel_in_sample && p->indel == 0 && b != 0) { // This read doesn't contain an indel in CIGAR, but it // is assigned to an indel now (b != 0), These are // reads we've corrected with realignment, but they're // also enriched for FPs so at high depth we reduce their // confidence and let the depth do the talking. If it's // real and deep, then we don't need every read aligning. // We also reduce base quality too to reflect the // chance of our realignment being incorrect. seqQ = MIN(seqQ, seqQ/2 + 5); // q2p5 // Finally reduce indel quality. // This is a blend of indelQ and base QUAL. q = MIN((int)bam_get_qual(p->b)[p->qpos]/4+10, q/4+1); } } #endif // Note baseQ changes some output fields such as I16, but has no // significant affect on "call". baseQ = p->aux>>8&0xff; } else { b = bam_seqi(bam_get_seq(p->b), p->qpos); // base b = seq_nt16_int[b? b : ref_base]; // b is the 2-bit base // Lowest of this and neighbour quality values uint8_t *qual = bam_get_qual(p->b); q = qual[p->qpos]; if (p->qpos > 0 && q > qual[p->qpos-1]+bca->delta_baseQ) q = qual[p->qpos-1]+bca->delta_baseQ; if (p->qpos+1 < p->b->core.l_qseq && q > qual[p->qpos+1]+bca->delta_baseQ) q = qual[p->qpos+1]+bca->delta_baseQ; if (q < bca->min_baseQ) continue; if (q > bca->max_baseQ) q = bca->max_baseQ; baseQ = q; seqQ = 99; is_diff = (ref4 < 4 && b == ref4)? 0 : 1; if ( bca->fmt_flag&(B2B_FMT_NMBZ|B2B_INFO_NMBZ|B2B_INFO_NM) ) { inm = get_aux_nm(p,p->qpos,is_diff?0:1); if ( inm>=0 ) { bca->nnm[is_diff]++; bca->nm[is_diff] += inm; } } } mapQ = p->b->core.qual < 255? p->b->core.qual : DEF_MAPQ; // special case for mapQ==255 if ( !mapQ ) r->mq0++; #ifdef GLF_DEBUG fprintf(stderr, "GLF2 %s\t%d\t%d\t%d,%d\n", bam_get_qname(p->b), b, q, seqQ, mapQ); #endif if (q > seqQ) q = seqQ; mapQ = mapQ < bca->capQ? mapQ : bca->capQ; if (q > mapQ) q = mapQ; if (q > 63) q = 63; if (q < 4) q = 4; // MQ=0 reads count as BQ=4 bca->bases[n++] = q<<5 | (int)bam_is_rev(p->b)<<4 | b; //if (is_indel) fprintf(stderr,"xx:base,q,strand\t%d\t%d\t%d\n",b,q,bam_is_rev(p->b)?0:1); // collect annotations if (b < 4) { r->QS[b] += q; if ( r->ADF ) { if ( bam_is_rev(p->b) ) r->ADR[b]++; else r->ADF[b]++; } } ++r->anno[0<<2|is_diff<<1|bam_is_rev(p->b)]; min_dist = p->b->core.l_qseq - 1 - p->qpos; if (min_dist > p->qpos) min_dist = p->qpos; if (min_dist > CAP_DIST) min_dist = CAP_DIST; r->anno[1<<2|is_diff<<1|0] += baseQ; r->anno[1<<2|is_diff<<1|1] += baseQ * baseQ; r->anno[2<<2|is_diff<<1|0] += mapQ; r->anno[2<<2|is_diff<<1|1] += mapQ * mapQ; r->anno[3<<2|is_diff<<1|0] += min_dist; r->anno[3<<2|is_diff<<1|1] += min_dist * min_dist; // collect for bias tests if ( baseQ > 59 ) baseQ = 59; if ( mapQ > 59 ) mapQ = 59; int len, epos = 0, sc_len = 0, sc_dist = 0; if ( bca->fmt_flag & (B2B_INFO_RPBZ|B2B_INFO_VDB|B2B_INFO_SCBZ) ) { int pos = get_position(p, &len, &sc_len, &sc_dist); epos = (double)pos/(len+1) * (bca->npos - 1); if (sc_len) { sc_len = 15.0*sc_len / (sc_dist+1); if (sc_len > 99) sc_len = 99; } assert( epos>=0 && eposnpos ); assert( sc_len>=0 && sc_lennpos ); } int imq = mapQ * nqual_over_60; int ibq = baseQ * nqual_over_60; if ( bam_is_rev(p->b) ) bca->rev_mqs[imq]++; else bca->fwd_mqs[imq]++; if ( !is_diff ) { bca->ref_pos[epos]++; bca->ref_bq[ibq]++; bca->ref_mq[imq]++; bca->ref_scl[sc_len]++; if ( inm>=0 ) { bca->ref_nm[inm]++; if ( r->ref_nm ) r->ref_nm[inm]++; } } else { bca->alt_pos[epos]++; bca->alt_bq[ibq]++; bca->alt_mq[imq]++; bca->alt_scl[sc_len]++; if ( inm>=0 ) { bca->alt_nm[inm]++; if ( r->alt_nm ) r->alt_nm[inm]++; } } } // Compensate for AD not being counted on low quality REF indel matches. if ( r->ADF && bca->ambig_reads==B2B_INC_AD0 ) { for (i=0; i<4; i++) { r->ADR[0] += ADR_ref_missed[i]; r->ADF[0] += ADF_ref_missed[i]; } } else if ( r->ADF && bca->ambig_reads==B2B_INC_AD ) { int dp = 0, dp_ambig = 0; for (i=0; i<4; i++) dp += r->ADR[i]; for (i=0; i<4; i++) dp_ambig += ADR_ref_missed[i]; if ( dp ) for (i=0; i<4; i++) r->ADR[i] += lroundf((float)dp_ambig * r->ADR[i]/dp); dp = 0, dp_ambig = 0; for (i=0; i<4; i++) dp += r->ADF[i]; for (i=0; i<4; i++) dp_ambig += ADF_ref_missed[i]; if ( dp ) for (i=0; i<4; i++) r->ADF[i] += lroundf((float)dp_ambig * r->ADF[i]/dp); } // Else consider downgrading bca->bases[] scores by AD vs AD_ref_missed // ratios. This is detrimental on Illumina, but beneficial on PacBio CCS. // It's possibly related to the homopolyer error likelihoods or overall // Indel accuracy. Maybe tie this in to the -h option? r->ori_depth = ori_depth; // glfgen errmod_cal(bca->e, n, 5, bca->bases, r->p); // calculate PL of each genotype // TODO: account for the number of unassigned reads. If depth is 50, // but AD is 5,7 then it may look like a variant but it probably // should be low quality. return n; } /* * calc_vdb() - returns value between zero (most biased) and one (no bias) * on success, or HUGE_VAL when VDB cannot be calculated because * of insufficient depth (<2x) * * Variant Distance Bias tests if the variant bases are positioned within the * reads with sufficient randomness. Unlike other tests, it looks only at * variant reads and therefore gives different kind of information than Read * Position Bias for instance. VDB was developed for detecting artefacts in * RNA-seq calls where reads from spliced transcripts span splice site * boundaries. The current implementation differs somewhat from the original * version described in supplementary material of PMID:22524474, but the idea * remains the same. (Here the random variable tested is the average distance * from the averaged position, not the average pairwise distance.) * * For coverage of 2x, the calculation is exact but is approximated for the * rest. The result is most accurate between 4-200x. For 3x or >200x, the * reported values are slightly more favourable than those of a true random * distribution. */ double calc_vdb(int *pos, int npos) { // Note well: the parameters were obtained by fitting to simulated data of // 100bp reads. This assumes rescaling to 100bp in bcf_call_glfgen(). const int readlen = 100; assert( npos==readlen ); #define nparam 15 const float param[nparam][3] = { {3,0.079,18}, {4,0.09,19.8}, {5,0.1,20.5}, {6,0.11,21.5}, {7,0.125,21.6}, {8,0.135,22}, {9,0.14,22.2}, {10,0.153,22.3}, {15,0.19,22.8}, {20,0.22,23.2}, {30,0.26,23.4}, {40,0.29,23.5}, {50,0.35,23.65}, {100,0.5,23.7}, {200,0.7,23.7} }; int i, dp = 0; float mean_pos = 0, mean_diff = 0; for (i=0; i=200 ) i = nparam; // shortcut for big depths else { for (i=0; i=dp ) break; } float pshift, pscale; if ( i==nparam ) { // the depth is too high, go with 200x pscale = param[nparam-1][1]; pshift = param[nparam-1][2]; } else if ( i>0 && param[i][0]!=dp ) { // linear interpolation of parameters pscale = (param[i-1][1] + param[i][1])*0.5; pshift = (param[i-1][2] + param[i][2])*0.5; } else { pscale = param[i][1]; pshift = param[i][2]; } return 0.5*kf_erfc(-(mean_diff-pshift)*pscale); } double calc_chisq_bias(int *a, int *b, int n) { int na = 0, nb = 0, i, ndf = n; for (i=0; i= 2 && m >= 2); return (n < 8 && m < 8 && U < 50) ? mw[n-2][m-2][U] : mann_whitney_1947_(n,m,U); } double mann_whitney_1947_cdf(int n, int m, int U) { int i; double sum = 0; for (i=0; i<=U; i++) sum += mann_whitney_1947(n,m,i); return sum; } double calc_mwu_bias_cdf(int *a, int *b, int n) { int na = 0, nb = 0, i; double U = 0; //double ties = 0; for (i=0; i=8 && nb>=8 and reasonable if na<8 or nb<8 if ( na>=8 || nb>=8 ) { double mean = ((double)na*nb)*0.5; // Correction for ties: // double N = na+nb; // double var2 = (N*N-1)*N-ties; // if ( var2==0 ) return 1.0; // var2 *= ((double)na*nb)/N/(N-1)/12.0; // No correction for ties: double var2 = ((double)na*nb)*(na+nb+1)/12.0; double z = (U_min - mean)/sqrt(2*var2); // z is N(0,1) return 2.0 - kf_erfc(z); // which is 1 + erf(z) } // Exact calculation double pval = 2*mann_whitney_1947_cdf(na,nb,U_min); return pval>1 ? 1 : pval; } double calc_mwu_bias(int *a, int *b, int n, int left) { int na = 0, nb = 0, i; double U = 0; // double ties = 0; for (i=0; i mean) return 1; // for MQB which is asymmetrical if ( na==2 || nb==2 ) { // Linear approximation return U>mean ? (2.0*mean-U)/mean : U/mean; } // Correction for ties: // double N = na+nb; // double var2 = (N*N-1)*N-ties; // if ( var2==0 ) return 1.0; // var2 *= ((double)na*nb)/N/(N-1)/12.0; // No correction for ties: double var2 = ((double)na*nb)*(na+nb+1)/12.0; if ( na>=8 || nb>=8 ) { // Normal approximation, very good for na>=8 && nb>=8 and reasonable if na<8 or nb<8 return exp(-0.5*(U-mean)*(U-mean)/var2); } // Exact calculation return mann_whitney_1947(na,nb,U) * sqrt(2*M_PI*var2); } // A Z-score version of the above function. // // See "Normal approximation and tie correction" at // https://en.wikipedia.org/wiki/Mann%E2%80%93Whitney_U_test // // The Z score is the number of standard deviations above or below the mean // with 0 being equality of the two distributions and +ve/-ve from there. // // This is a more robust score to filter on. double calc_mwu_biasZ(int *a, int *b, int n, int left_only, int do_Z) { int i; int64_t t; // Optimisation for (i = 0; i < n; i++) if (b[i]) break; int b_empty = (i == n); // Count equal (e), less-than (l) and greater-than (g) permutations. int e = 0, l = 0, na = 0, nb = 0; if (b_empty) { for (t = 0, i = n-1; i >= 0; i--) { na += a[i]; t += (a[i]*a[i]-1)*a[i]; // adjustment score for ties } } else { for (t = 0, i = n-1; i >= 0; i--) { // Combinations of a[i] and b[j] for i==j e += a[i]*b[i]; // nb is running total of b[i+1]..b[n-1]. // Therefore a[i]*nb is the number of combinations of a[i] and b[j] // for all i < j. l += a[i]*nb; // a= 0 ? 0.5 : -0.5)) / sd; // gatk method? return (U - m) / sqrt(var2); } // Else U score, which can be asymmetric for some data types. if (left_only && U > m) return HUGE_VAL; // one-sided, +ve bias is OK, -ve is not. if (na >= 8 || nb >= 8) { // Normal approximation, very good for na>=8 && nb>=8 and // reasonable if na<8 or nb<8 return exp(-0.5*(U-m)*(U-m)/var2); } // Exact calculation if (na==1 || nb == 1) return mann_whitney_1947_(na, nb, U) * sqrt(2*M_PI*var2); else return mann_whitney_1947(na, nb, U) * sqrt(2*M_PI*var2); } static inline double logsumexp2(double a, double b) { if ( a>b ) return log(1 + exp(b-a)) + a; else return log(1 + exp(a-b)) + b; } void calc_SegBias(const bcf_callret1_t *bcr, bcf_call_t *call) { call->seg_bias = HUGE_VAL; if ( !bcr ) return; int nr = call->anno[2] + call->anno[3]; // number of observed non-reference reads if ( !nr ) return; int avg_dp = (call->anno[0] + call->anno[1] + nr) / call->n; // average depth double M = floor((double)nr / avg_dp + 0.5); // an approximate number of variants samples in the population if ( M>call->n ) M = call->n; // clamp M at the number of samples else if ( M==0 ) M = 1; double f = M / 2. / call->n; // allele frequency double p = (double) nr / call->n; // number of variant reads per sample expected if variant not real (poisson) double q = (double) nr / M; // number of variant reads per sample expected if variant is real (poisson) double sum = 0; const double log2 = log(2.0); // fprintf(stderr,"M=%.1f p=%e q=%e f=%f dp=%d\n",M,p,q,f,avg_dp); int i; for (i=0; in; i++) { int oi = bcr[i].anno[2] + bcr[i].anno[3]; // observed number of non-ref reads double tmp; if ( oi ) { // tmp = log(f) + oi*log(q/p) - q + log(2*(1-f) + f*pow(2,oi)*exp(-q)) + p; // this can under/overflow tmp = logsumexp2(log(2*(1-f)), log(f) + oi*log2 - q); tmp += log(f) + oi*log(q/p) - q + p; } else tmp = log(2*f*(1-f)*exp(-q) + f*f*exp(-2*q) + (1-f)*(1-f)) + p; sum += tmp; // fprintf(stderr,"oi=%d %e\n", oi,tmp); } call->seg_bias = sum; } /** * bcf_call_combine() - sets the PL array and VDB, RPB annotations, finds the top two alleles * @n: number of samples * @calls: each sample's calls * @bca: auxiliary data structure for holding temporary values * @ref_base: the reference base * @call: filled with the annotations * * Combines calls across the various samples being studied * 1. For each allele at each base across all samples the quality is summed so * you end up with a set of quality sums for each allele present 2. The quality * sums are sorted. * 3. Using the sorted quality sums we now create the allele ordering array * A\subN. This is done by doing the following: * a) If the reference allele is known it always comes first, otherwise N * comes first. * b) Then the rest of the alleles are output in descending order of quality * sum (which we already know the qsum array was sorted). Any allelles with * qsum 0 will be excluded. * 4. Using the allele ordering array we create the genotype ordering array. * In the worst case with an unknown reference this will be: A0/A0 A1/A0 A1/A1 * A2/A0 A2/A1 A2/A2 A3/A0 A3/A1 A3/A2 A3/A3 A4/A0 A4/A1 A4/A2 A4/A3 A4/A4 * 5. The genotype ordering array is then used to extract data from the error * model 5*5 matrix and is used to produce a Phread likelihood array for each * sample. */ int bcf_call_combine(int n, const bcf_callret1_t *calls, bcf_callaux_t *bca, int ref_base /*4-bit*/, bcf_call_t *call) { int ref4, i, j; float qsum[B2B_MAX_ALLELES] = {0,0,0,0,0}; if (ref_base >= 0) { call->ori_ref = ref4 = seq_nt16_int[ref_base]; if (ref4 > 4) ref4 = 4; } else call->ori_ref = -1, ref4 = 0; // calculate qsum, this is done by summing normalized qsum across all samples, // to account for differences in coverage for (i = 0; i < n; ++i) { float sum = 0; for (j = 0; j < 4; ++j) sum += calls[i].QS[j]; if ( sum ) for (j = 0; j < 4; j++) qsum[j] += (float)calls[i].QS[j] / sum; } // sort qsum in ascending order (insertion sort) float *ptr[5], *tmp; for (i=0; i<5; i++) ptr[i] = &qsum[i]; for (i=1; i<4; i++) for (j=i; j>0 && *ptr[j] < *ptr[j-1]; j--) tmp = ptr[j], ptr[j] = ptr[j-1], ptr[j-1] = tmp; // Set the reference allele and alternative allele(s) for (i=0; i<5; i++) call->a[i] = -1; for (i=0; iqsum[i] = 0; call->unseen = -1; call->a[0] = ref4; for (i=3, j=1; i>=0; i--) // i: alleles sorted by QS; j, a[j]: output allele ordering { int ipos = ptr[i] - qsum; // position in sorted qsum array if ( ipos==ref4 ) call->qsum[0] = qsum[ipos]; // REF's qsum else { if ( !qsum[ipos] ) break; // qsum is 0, this and consequent alleles are not seen in the pileup call->qsum[j] = qsum[ipos]; call->a[j++] = ipos; } } if (ref_base >= 0) { // for SNPs, find the "unseen" base if (((ref4 < 4 && j < 4) || (ref4 == 4 && j < 5)) && i >= 0) call->unseen = j, call->a[j++] = ptr[i] - qsum; call->n_alleles = j; } else { call->n_alleles = j; if (call->n_alleles == 1) return -1; // no reliable supporting read. stop doing anything } int has_alt = (call->n_alleles==2 && call->unseen!=-1) ? 0 : 1; /* * Set the phread likelihood array (call->PL) This array is 15 entries long * for each sample because that is size of an upper or lower triangle of a * worst case 5x5 matrix of possible genotypes. This worst case matrix will * occur when all 4 possible alleles are present and the reference allele * is unknown. The sides of the matrix will correspond to the reference * allele (if known) followed by the alleles present in descending order of * quality sum */ { int x, g[15], z; double sum_min = 0.; x = call->n_alleles * (call->n_alleles + 1) / 2; // get the possible genotypes // this is done by creating an ordered list of locations g for call (allele a, allele b) in the genotype likelihood matrix for (i = z = 0; i < call->n_alleles; ++i) { for (j = 0; j <= i; ++j) { g[z++] = call->a[j] * 5 + call->a[i]; } } // for each sample calculate the PL for (i = 0; i < n; ++i) { int32_t *PL = call->PL + x * i; const bcf_callret1_t *r = calls + i; float min = FLT_MAX; for (j = 0; j < x; ++j) { if (min > r->p[g[j]]) min = r->p[g[j]]; } sum_min += min; for (j = 0; j < x; ++j) { int y; y = (int)(r->p[g[j]] - min + .499); if (y > 255) y = 255; PL[j] = y; } } if ( call->DP4 ) { for (i=0; iDP4[4*i] = calls[i].anno[0]; call->DP4[4*i+1] = calls[i].anno[1]; call->DP4[4*i+2] = calls[i].anno[2]; call->DP4[4*i+3] = calls[i].anno[3]; } } if ( call->SCR ) { for (i=0; iSCR[0] += calls[i].SCR; call->SCR[1+i] = calls[i].SCR; } } if ( call->ADF ) { assert( call->n_alleles<=B2B_MAX_ALLELES ); // this is always true for SNPs and so far for indels as well // reorder ADR,ADF to match the allele ordering at this site int32_t tmp[B2B_MAX_ALLELES]; int32_t *adr = call->ADR + B2B_MAX_ALLELES, *adr_out = call->ADR + B2B_MAX_ALLELES; int32_t *adf = call->ADF + B2B_MAX_ALLELES, *adf_out = call->ADF + B2B_MAX_ALLELES; int32_t *adr_tot = call->ADR; // the first bin stores total counts per site int32_t *adf_tot = call->ADF; for (i=0; in_alleles; j++) { tmp[j] = adr[ call->a[j] ]; adr_tot[j] += tmp[j]; } for (j=0; jn_alleles; j++) adr_out[j] = tmp[j]; for (j=0; jn_alleles; j++) { tmp[j] = adf[ call->a[j] ]; adf_tot[j] += tmp[j]; } for (j=0; jn_alleles; j++) adf_out[j] = tmp[j]; adf_out += call->n_alleles; adr_out += call->n_alleles; adr += B2B_MAX_ALLELES; adf += B2B_MAX_ALLELES; } } if ( bca->fmt_flag & B2B_FMT_QS ) { assert( call->n_alleles<=B2B_MAX_ALLELES ); // this is always true for SNPs and so far for indels as well // reorder QS to match the allele ordering at this site int32_t tmp[B2B_MAX_ALLELES]; int32_t *qs = call->QS, *qs_out = call->QS; for (i=0; in_alleles; j++) tmp[j] = qs[ call->a[j] ]; for (j=0; jn_alleles; j++) qs_out[j] = tmp[j] < BCF_MAX_BT_INT32 ? tmp[j] : BCF_MAX_BT_INT32; qs_out += call->n_alleles; qs += B2B_MAX_ALLELES; } } // if (ref_base < 0) fprintf(stderr, "%d,%d,%f,%d\n", call->n_alleles, x, sum_min, call->unseen); // fprintf(stderr,"sum_min=%f\n",sum_min); call->shift = (int)(sum_min + .499); } // combine annotations memset(call->anno, 0, 16 * sizeof(double)); call->ori_depth = 0; call->depth = 0; call->mq0 = 0; for (i = 0; i < n; ++i) { call->depth += calls[i].anno[0] + calls[i].anno[1] + calls[i].anno[2] + calls[i].anno[3]; call->ori_depth += calls[i].ori_depth; call->mq0 += calls[i].mq0; for (j = 0; j < 16; ++j) call->anno[j] += calls[i].anno[j]; } // No need to calculate MWU tests when there is no ALT allele, this should speed up things slightly if ( !has_alt ) return 0; if ( bca->fmt_flag & B2B_INFO_FS ) { double left,right,two; call->strand_bias = kt_fisher_exact(call->anno[0], call->anno[1], call->anno[2], call->anno[3], &left, &right, &two); } if ( bca->fmt_flag & B2B_INFO_SGB ) calc_SegBias(calls, call); // calc_chisq_bias("XPOS", call->bcf_hdr->id[BCF_DT_CTG][call->tid].key, call->pos, bca->ref_pos, bca->alt_pos, bca->npos); // calc_chisq_bias("XMQ", call->bcf_hdr->id[BCF_DT_CTG][call->tid].key, call->pos, bca->ref_mq, bca->alt_mq, bca->nqual); // calc_chisq_bias("XBQ", call->bcf_hdr->id[BCF_DT_CTG][call->tid].key, call->pos, bca->ref_bq, bca->alt_bq, bca->nqual); // U z-normalised as +/- number of standard deviations from mean. if (call->ori_ref < 0) { // indel if ( bca->fmt_flag & B2B_INFO_RPBZ ) call->mwu_pos = calc_mwu_biasZ(bca->iref_pos, bca->ialt_pos, bca->npos, 0, 1); if ( bca->fmt_flag & B2B_INFO_MQBZ ) call->mwu_mq = calc_mwu_biasZ(bca->iref_mq, bca->ialt_mq, bca->nqual,1,1); if ( bca->fmt_flag & B2B_INFO_SCBZ ) call->mwu_sc = calc_mwu_biasZ(bca->iref_scl, bca->ialt_scl, 100, 0,1); } else { if ( bca->fmt_flag & B2B_INFO_RPBZ ) call->mwu_pos = calc_mwu_biasZ(bca->ref_pos, bca->alt_pos, bca->npos, 0, 1); if ( bca->fmt_flag & B2B_INFO_MQBZ ) call->mwu_mq = calc_mwu_biasZ(bca->ref_mq, bca->alt_mq, bca->nqual,1,1); if ( bca->fmt_flag & B2B_INFO_BQBZ ) call->mwu_bq = calc_mwu_biasZ(bca->ref_bq, bca->alt_bq, bca->nqual,0,1); if ( bca->fmt_flag & B2B_INFO_MQSBZ ) call->mwu_mqs = calc_mwu_biasZ(bca->fwd_mqs, bca->rev_mqs, bca->nqual,0,1); if ( bca->fmt_flag & B2B_INFO_SCBZ ) call->mwu_sc = calc_mwu_biasZ(bca->ref_scl, bca->alt_scl, 100, 0,1); } if ( bca->fmt_flag & B2B_INFO_NMBZ ) call->mwu_nm[0] = calc_mwu_biasZ(bca->ref_nm, bca->alt_nm, B2B_N_NM,0,1); if ( bca->fmt_flag & B2B_FMT_NMBZ ) { for (i=0; imwu_nm[i+1] = val!=HUGE_VAL ? val : 0; } } if ( bca->fmt_flag & B2B_INFO_VDB ) call->vdb = calc_vdb(bca->alt_pos, bca->npos); return 0; } int bcf_call2bcf(bcf_call_t *bc, bcf1_t *rec, bcf_callret1_t *bcr, int fmt_flag, const bcf_callaux_t *bca, const char *ref) { extern double kt_fisher_exact(int n11, int n12, int n21, int n22, double *_left, double *_right, double *two); int i, j, nals = 1, has_alt = 0; bcf_hdr_t *hdr = bc->bcf_hdr; rec->rid = bc->tid; rec->pos = bc->pos; rec->qual = 0; bc->tmp.l = 0; if (bc->ori_ref < 0) // indel { // REF kputc(ref[bc->pos], &bc->tmp); for (j = 0; j < bca->indelreg; ++j) kputc(ref[bc->pos+1+j], &bc->tmp); // ALT for (i=1; i<4; i++) { if (bc->a[i] < 0) break; kputc(',', &bc->tmp); kputc(ref[bc->pos], &bc->tmp); if (bca->indel_types[bc->a[i]] < 0) { // deletion for (j = -bca->indel_types[bc->a[i]]; j < bca->indelreg; ++j) kputc(ref[bc->pos+1+j], &bc->tmp); } else { // insertion; cannot be a reference unless a bug char *inscns = &bca->inscns[bc->a[i] * bca->maxins]; for (j = 0; j < bca->indel_types[bc->a[i]]; ++j) kputc("ACGTN"[(int)inscns[j]], &bc->tmp); for (j = 0; j < bca->indelreg; ++j) kputc(ref[bc->pos+1+j], &bc->tmp); } nals++; has_alt = 1; } } else // SNP { kputc("ACGTN"[bc->ori_ref], &bc->tmp); for (i=1; i<5; i++) { if (bc->a[i] < 0) break; kputc(',', &bc->tmp); if ( bc->unseen==i ) kputs("<*>", &bc->tmp); else { kputc("ACGT"[bc->a[i]], &bc->tmp); has_alt = 1; } nals++; } } bcf_update_alleles_str(hdr, rec, bc->tmp.s); bc->tmp.l = 0; // INFO if ( bc->ori_ref < 0 ) { bcf_update_info_flag(hdr, rec, "INDEL", NULL, 1); uint32_t idv = bca->max_support; if ( fmt_flag&B2B_INFO_IMF) { float max_frac; // Recompute IDV and IMF based on alignment results for more // accurate counts, but only when in new "--indels-cns" mode. if (bc->ADF && bc->ADR && bca->edlib) { int max_ad = 0; for (int k = 1; k < rec->n_allele; k++) { if (max_ad < bc->ADF[k] + bc->ADR[k]) max_ad = bc->ADF[k] + bc->ADR[k]; } max_frac = (double)(max_ad) / bc->ori_depth; idv = max_ad; } else { max_frac = bca->max_frac; } // Copied here to maintain order for consistency of "make check" if ( fmt_flag&B2B_INFO_IDV ) bcf_update_info_int32(hdr, rec, "IDV", &idv, 1); bcf_update_info_float(hdr, rec, "IMF", &max_frac, 1); } else { if ( fmt_flag&B2B_INFO_IDV ) bcf_update_info_int32(hdr, rec, "IDV", &idv, 1); } } bcf_update_info_int32(hdr, rec, "DP", &bc->ori_depth, 1); if ( fmt_flag&B2B_INFO_ADF ) bcf_update_info_int32(hdr, rec, "ADF", bc->ADF, rec->n_allele); if ( fmt_flag&B2B_INFO_ADR ) bcf_update_info_int32(hdr, rec, "ADR", bc->ADR, rec->n_allele); if ( fmt_flag&(B2B_INFO_AD|B2B_INFO_DPR) ) { for (i=0; in_allele; i++) bc->ADF[i] += bc->ADR[i]; if ( fmt_flag&B2B_INFO_AD ) bcf_update_info_int32(hdr, rec, "AD", bc->ADF, rec->n_allele); if ( fmt_flag&B2B_INFO_DPR ) bcf_update_info_int32(hdr, rec, "DPR", bc->ADF, rec->n_allele); } if ( fmt_flag&B2B_INFO_SCR ) bcf_update_info_int32(hdr, rec, "SCR", bc->SCR, 1); float tmpf[16]; for (i=0; i<16; i++) tmpf[i] = bc->anno[i]; bcf_update_info_float(hdr, rec, "I16", tmpf, 16); bcf_update_info_float(hdr, rec, "QS", bc->qsum, nals); if ( has_alt ) { if ( fmt_flag&B2B_INFO_MIN_PL_SUM ) bcf_update_info_int32(hdr, rec, "MIN_PL_SUM", &bc->shift, 1); if ( fmt_flag&B2B_INFO_VDB && bc->vdb != HUGE_VAL ) bcf_update_info_float(hdr, rec, "VDB", &bc->vdb, 1); if ( fmt_flag&B2B_INFO_SGB && bc->seg_bias != HUGE_VAL ) bcf_update_info_float(hdr, rec, "SGB", &bc->seg_bias, 1); if ( fmt_flag&B2B_INFO_NM && (bca->nnm[0] || bca->nnm[1]) ) { for (i=0; i<2; i++) bc->nm[i] = bca->nnm[i] ? bca->nm[i]/bca->nnm[i] : 0; bcf_update_info_float(hdr, rec, "NM", bc->nm, 2); } if ( fmt_flag&B2B_INFO_RPBZ && bc->mwu_pos != HUGE_VAL ) bcf_update_info_float(hdr, rec, "RPBZ", &bc->mwu_pos, 1); if ( fmt_flag&B2B_INFO_MQBZ && bc->mwu_mq != HUGE_VAL ) bcf_update_info_float(hdr, rec, "MQBZ", &bc->mwu_mq, 1); if ( fmt_flag&B2B_INFO_MQSBZ && bc->mwu_mqs != HUGE_VAL ) bcf_update_info_float(hdr, rec, "MQSBZ", &bc->mwu_mqs, 1); if ( fmt_flag&B2B_INFO_BQBZ && bc->mwu_bq != HUGE_VAL ) bcf_update_info_float(hdr, rec, "BQBZ", &bc->mwu_bq, 1); if ( fmt_flag&B2B_INFO_NMBZ && bc->mwu_nm[0] != HUGE_VAL ) bcf_update_info_float(hdr, rec, "NMBZ", bc->mwu_nm, 1); if ( fmt_flag&B2B_INFO_SCBZ && bc->mwu_sc != HUGE_VAL ) bcf_update_info_float(hdr, rec, "SCBZ", &bc->mwu_sc, 1); if ( fmt_flag&B2B_INFO_FS && bc->strand_bias != HUGE_VAL ) bcf_update_info_float(hdr, rec, "FS", &bc->strand_bias, 1); } tmpf[0] = bc->ori_depth ? (float)bc->mq0/bc->ori_depth : 0; if ( fmt_flag&B2B_INFO_MQ0F ) bcf_update_info_float(hdr, rec, "MQ0F", tmpf, 1); // FORMAT rec->n_sample = bc->n; bcf_update_format_int32(hdr, rec, "PL", bc->PL, nals*(nals+1)/2 * rec->n_sample); if ( fmt_flag&B2B_FMT_DP ) { int32_t *ptr = (int32_t*) bc->fmt_arr; for (i=0; in; i++) ptr[i] = bc->DP4[4*i] + bc->DP4[4*i+1] + bc->DP4[4*i+2] + bc->DP4[4*i+3]; bcf_update_format_int32(hdr, rec, "DP", bc->fmt_arr, rec->n_sample); } if ( fmt_flag&B2B_FMT_DV ) { int32_t *ptr = (int32_t*) bc->fmt_arr; for (i=0; in; i++) ptr[i] = bc->DP4[4*i+2] + bc->DP4[4*i+3]; bcf_update_format_int32(hdr, rec, "DV", bc->fmt_arr, rec->n_sample); } if ( fmt_flag&B2B_FMT_SP ) { int32_t *ptr = (int32_t*) bc->fmt_arr; for (i=0; in; i++) { int fwd_ref = bc->DP4[4*i], rev_ref = bc->DP4[4*i+1], fwd_alt = bc->DP4[4*i+2], rev_alt = bc->DP4[4*i+3]; if ( fwd_ref+rev_ref<2 || fwd_alt+rev_alt<2 || fwd_ref+fwd_alt<2 || rev_ref+rev_alt<2 ) ptr[i] = 0; else { double left, right, two; kt_fisher_exact(fwd_ref, rev_ref, fwd_alt, rev_alt, &left, &right, &two); int32_t x = (int)(-4.343 * log(two) + .499); if (x > 255) x = 255; ptr[i] = x; } } bcf_update_format_int32(hdr, rec, "SP", bc->fmt_arr, rec->n_sample); } if ( fmt_flag&B2B_FMT_DP4 ) bcf_update_format_int32(hdr, rec, "DP4", bc->DP4, rec->n_sample*4); if ( fmt_flag&B2B_FMT_ADF ) bcf_update_format_int32(hdr, rec, "ADF", bc->ADF+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); if ( fmt_flag&B2B_FMT_ADR ) bcf_update_format_int32(hdr, rec, "ADR", bc->ADR+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); if ( fmt_flag&(B2B_FMT_AD|B2B_FMT_DPR) ) { for (i=0; in_sample*rec->n_allele; i++) bc->ADF[B2B_MAX_ALLELES+i] += bc->ADR[B2B_MAX_ALLELES+i]; if ( fmt_flag&B2B_FMT_AD ) bcf_update_format_int32(hdr, rec, "AD", bc->ADF+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); if ( fmt_flag&B2B_FMT_DPR ) bcf_update_format_int32(hdr, rec, "DPR", bc->ADF+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); } if ( fmt_flag&B2B_FMT_SCR ) bcf_update_format_int32(hdr, rec, "SCR", bc->SCR+1, rec->n_sample); if ( fmt_flag&B2B_FMT_QS ) bcf_update_format_int32(hdr, rec, "QS", bc->QS, rec->n_sample*rec->n_allele); if ( has_alt ) { if ( fmt_flag&B2B_FMT_NMBZ ) bcf_update_format_float(hdr, rec, "NMBZ", bc->mwu_nm+1, rec->n_sample); } return 0; } bcftools-1.21/bam2bcf.h000066400000000000000000000224011467060157400147260ustar00rootroot00000000000000/* bam2bcf.h -- variant calling. Copyright (C) 2010-2012 Broad Institute. Copyright (C) 2012-2022 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef BAM2BCF_H #define BAM2BCF_H #include #include #include /** * A simplified version of Mann-Whitney U-test is calculated * by default (no CDF) because it is faster and seems to work * better in machine learning filtering. When enabled by setting * CDF_MWU_TESTS, additional annotations will appear on mpileup's * output (RPB2 in addition to RPB, etc.). */ #ifndef CDF_MWU_TESTS #define CDF_MWU_TESTS 0 #endif #define B2B_INDEL_NULL 10000 #define B2B_FMT_DP (1<<0) #define B2B_FMT_SP (1<<1) #define B2B_FMT_DV (1<<2) #define B2B_FMT_DP4 (1<<3) #define B2B_FMT_DPR (1<<4) #define B2B_INFO_DPR (1<<5) #define B2B_FMT_AD (1<<6) #define B2B_FMT_ADF (1<<7) #define B2B_FMT_ADR (1<<8) #define B2B_INFO_AD (1<<9) #define B2B_INFO_ADF (1<<10) #define B2B_INFO_ADR (1<<11) #define B2B_INFO_SCR (1<<12) #define B2B_FMT_SCR (1<<13) #define B2B_INFO_VDB (1<<14) #define B2B_FMT_QS (1<<15) #define B2B_FMT_NMBZ (1<<16) // per-sample NMBZ #define B2B_INFO_NMBZ (1<<17) #define B2B_INFO_BQBZ (1<<18) #define B2B_INFO_MQBZ (1<<19) #define B2B_INFO_MQSBZ (1<<20) #define B2B_INFO_RPBZ (1<<21) #define B2B_INFO_SCBZ (1<<22) #define B2B_INFO_SGB (1<<23) #define B2B_INFO_MIN_PL_SUM (1<<24) #define B2B_INFO_NM (1<<25) #define B2B_INFO_MQ0F (1<<26) #define B2B_INFO_IDV (1<<27) #define B2B_INFO_IMF (1<<28) #define B2B_INFO_FS (1<<29) #define B2B_MAX_ALLELES 5 #define B2B_N_NM 32 // number of NMBZ bins, i.e. max number of mismatches #define B2B_DROP 0 #define B2B_INC_AD 1 #define B2B_INC_AD0 2 // Pileup "client data" for each read to cache per-read information #define PLP_CD(x) ((plp_cd_t*)((x)->p)) #define PLP_HAS_SOFT_CLIP(cd) (PLP_CD(cd)->i & 1) #define PLP_HAS_INDEL(cd) (PLP_CD(cd)->i & 2) #define PLP_IS_REALN(cd) (PLP_CD(cd)->i & 4) #define PLP_SAMPLE_ID(cd) (PLP_CD(cd)->i >> 3) #define PLP_QLEN(cd) (PLP_CD(cd)->qlen) #define PLP_NM(cd) (PLP_CD(cd)->nm) #define PLP_NM_UNSET -2 #define PLP_SET_SOFT_CLIP(cd) (PLP_CD(cd)->i |= 1) #define PLP_SET_INDEL(cd) (PLP_CD(cd)->i |= 2) #define PLP_SET_REALN(cd) (PLP_CD(cd)->i |= 4) #define PLP_SET_SAMPLE_ID(cd,n) (PLP_CD(cd)->i |= (n)<<3) typedef struct { int64_t i; // used to store sample id and flags for presence of soft-clip and indel uint32_t qlen; // cached output of bam_cigar2qlen(), 0 if unset int nm; // -2 PLP_NM_UNSET; -1 not available; >=0 NM value computed by get_aux_nm() } plp_cd_t; typedef struct __bcf_callaux_t { int fmt_flag, ambig_reads; int capQ, min_baseQ, max_baseQ, delta_baseQ; int openQ, extQ, tandemQ; // for indels uint32_t min_support, max_support; // for collecting indel candidates double min_frac; // for collecting indel candidates float max_frac; // for collecting indel candidates int per_sample_flt; // indel filtering strategy int *ref_pos, *alt_pos, npos, *ref_mq, *alt_mq, *ref_bq, *alt_bq, *fwd_mqs, *rev_mqs, nqual; // for bias tests int *iref_pos, *ialt_pos, *iref_mq, *ialt_mq; // for indels int ref_scl[100], alt_scl[100]; // soft-clip length bias; SNP int iref_scl[100], ialt_scl[100]; // soft-clip length bias; INDEL // for internal uses int max_bases; int indel_types[4]; // indel lengths int indel_win_size, indels_v20, edlib; int seqQ_offset; // edlib mode, seqQ=MIN(seqQ, offset - MIN(20,depth)*5); int maxins, indelreg, poly_mqual; int read_len; char *inscns; uint16_t *bases; // 5bit: unused, 6:quality, 1:is_rev, 4:2-bit base or indel allele (index to bcf_callaux_t.indel_types) errmod_t *e; void *rghash; float indel_bias; // adjusts indel score threshold; lower => call more. float del_bias; // (-.9 < x < .9) error profile; >0 => more del, <0 => more ins float vs_ref; // 0 to 1. 0: score vs next-best. 1: score vs ref int32_t *ref_nm, *alt_nm; // pointers to bcf_call_t.{ref_nm,alt_nm} unsigned int nnm[2]; // number of nm observations float nm[2]; // cumulative count of mismatches in ref and alt reads void *iaux; // auxiliary structure for --indels-2.0 calling char *chr; // current chromosome } bcf_callaux_t; // per-sample values typedef struct { uint32_t ori_depth; // ori_depth = anno[0..3] but before --min-BQ is applied unsigned int mq0; int32_t *ADF, *ADR, SCR, *QS; // FMT/QS int32_t *ref_nm, *alt_nm; // The fields are: // depth fwd .. ref (0) and non-ref (2) // depth rev .. ref (1) and non-ref (3) // baseQ .. ref (4) and non-ref (6) // baseQ^2 .. ref (5) and non-ref (7) // mapQ .. ref (8) and non-ref (10) // mapQ^2 .. ref (9) and non-ref (11) // minDist .. ref (12) and non-ref (14) // minDist^2 .. ref (13) and non-ref (15) // Note that this probably needs a more thorough fix: int types in // bcf_call_t do overflow with high-coverage data, such as exomes, and // BCFv2 supports only floats which may not suffice. double anno[16]; float p[25]; // phred-scaled likelihood of each genotype } bcf_callret1_t; // values for all samples typedef struct { int tid, pos; bcf_hdr_t *bcf_hdr; int a[5]; // alleles: ref, alt, alt2, alt3 float qsum[B2B_MAX_ALLELES]; // INFO/QS tag int n, n_alleles, ori_ref, unseen; int32_t shift; // shift is the sum of min_PL before normalization to 0 across all samples int n_supp; // number of supporting non-reference reads double anno[16]; unsigned int depth, ori_depth, mq0; int32_t *PL, *DP4, *ADR, *ADF, *SCR, *QS, *ref_nm, *alt_nm; uint8_t *fmt_arr; float vdb; // variant distance bias float mwu_pos, mwu_mq, mwu_bq, mwu_mqs, mwu_sc, *mwu_nm, nm[2]; float seg_bias; float strand_bias; // phred-scaled fisher-exact test kstring_t tmp; } bcf_call_t; #ifdef __cplusplus extern "C" { #endif bcf_callaux_t *bcf_call_init(double theta, int min_baseQ, int max_baseQ, int delta_baseQ); void bcf_call_destroy(bcf_callaux_t *bca); int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r); int bcf_call_combine(int n, const bcf_callret1_t *calls, bcf_callaux_t *bca, int ref_base /*4-bit*/, bcf_call_t *call); int bcf_call2bcf(bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int fmt_flag, const bcf_callaux_t *bca, const char *ref); int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref); int bcf_iaux_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref); int bcf_edlib_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, int ref_len); void bcf_callaux_clean(bcf_callaux_t *bca, bcf_call_t *call); int bcf_cgp_l_run(const char *ref, int pos); int est_indelreg(int pos, const char *ref, int l, char *ins4); /* ---------------------------------------------------------------------- * Shared between bam2bcf_indel.c and bam2bcf_edlib.c */ // Take a reference position tpos and convert to a query position (returned). // This uses the CIGAR string plus alignment c->pos to do the mapping. // // *_tpos is returned as tpos if query overlaps tpos, but for deletions // it'll be either the start (is_left) or end (!is_left) ref position. int tpos2qpos(const bam1_core_t *c, const uint32_t *cigar, int32_t tpos, int is_left, int32_t *_tpos); // Identify spft-clip length, position in seq, and clipped seq len void get_pos(const bcf_callaux_t *bca, bam_pileup1_t *p, int *sc_len_r, int *slen_r, int *epos_r, int *end); // Compute the consensus for this sample 's', minus indels which // get added later. char *bcf_cgp_calc_cons(int n, int *n_plp, bam_pileup1_t **plp, int pos, int *types, int n_types, int max_ins, int s); #ifdef __cplusplus } #endif #endif bcftools-1.21/bam2bcf_edlib.c000066400000000000000000002034221467060157400160640ustar00rootroot00000000000000/* bam2bcf_indel.c -- indel caller. Copyright (C) 2010, 2011 Broad Institute. Copyright (C) 2012-2014,2016-2017, 2021-2024 Genome Research Ltd. Author: Heng Li Petr Danecek James Bonfield Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ // Show consensus //#define CONS_DEBUG // Show alignments to consensus //#define ALIGN_DEBUG #include #include #include #include #include #include #include #include "bam2bcf.h" #include "str_finder.h" #include // Is there no way to share these between the 3 implementations? KSORT_INIT_STATIC_GENERIC(uint32_t) #define MINUS_CONST 0x10000000 #define MAX_TYPES 64 #ifndef MIN # define MIN(a,b) ((a)<(b)?(a):(b)) #endif #ifndef ABS # define ABS(a) ((a)<0?-(a):(a)) #endif #ifndef MAX # define MAX(a,b) ((a)>(b)?(a):(b)) #endif // l is the relative gap length and l_run is the length of the homopolymer // on the reference. // // Larger seqQ is good, so increasing tandemQ calls more indels, // and longer l_run means fewer calls. It is capped later at 255. // For short l_runs, the qual is simply based on size of indel // larger ones being considered more likely to be real. // Longer indels get assigned a score based on the relative indel size // to homopolymer, where l_run base will have already been verified by // the caller to ensure it's compatible. static inline int est_seqQ(const bcf_callaux_t *bca, int l, int l_run, int str_len) { int q, qh; // Short indels are more likely sequencing error than large ones. // So "seqQ" scales with size of observation "l". // // Note openQ and extQ are error likelihoods in Phred scale. Hence high // openQ means we're very unlikely to miscall an indel. // Ie it's not the open/ext "costs" normally used in alignment; more the reverse. // // We use MIN(q,qh) below, so we can remove the q component by specifying // a large -o parameter in mpileup. q = bca->openQ + bca->extQ * (abs(l) - 1); // Orig method; best with Illumina (high openQ) // qh = bca->tandemQ * (double)abs(l) / l_run + .499; // Penalise longer homopolymers quadratically more, but boost shorter ones. // Best with CCS (low openQ) //qh = 2 * bca->tandemQ * pow((double)abs(l) / l_run, 1.5) + .499; // (l/l_run)^1.26 for openQ=25 or ^1 for openQ=40. // double openQ = MIN(40, bca->openQ); // qh = (30/openQ) * bca->tandemQ // * pow((double)abs(l) / l_run, 1/sqrt(openQ/40)) + .499; // Linear scaled on openQ too qh = bca->tandemQ * (double)abs(l) / l_run + .499; // Generic maybe ? // power = 1/sqrt(MIN(40,bca->openQ)/40.); // qh = ... * pow((double)abs(l)/l_run, power) // bam2bcf.c caps has "if q>seqQ) q=seqQ" so it caps base qual 'q'. // A 1bp indel would therefore have a maximum qual it could be considered based // on open+ext. Hence why openQ is phred score indicating if the base is real // or an over/under-call. (high openQ means high trust in base) return q < qh? q : qh; } // Part of bcf_call_gap_prep. // // Scans the pileup to identify all the different sizes of indels // present. // types[] returned is sorted by size, from smallest (maybe negative) to largest. // // Returns types and fills out n_types_r, max_rd_len_r and ref_type_r, // or NULL on error. static int *bcf_cgp_find_types(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, int *max_rd_len_r, int *n_types_r, int *ref_type_r, int *N_r) { int i, j, t, s, N, m, max_rd_len, n_types; int n_alt = 0, n_tot = 0, indel_support_ok = 0; uint32_t *aux; int *types; // N is the total number of reads for (s = N = 0; s < n; ++s) N += n_plp[s]; bca->max_support = bca->max_frac = 0; aux = (uint32_t*) calloc(N + 1, 4); if (!aux) return NULL; m = max_rd_len = 0; aux[m++] = MINUS_CONST; // zero indel is always a type (REF) // Fill out aux[] array with all the non-zero indel sizes. // Also tally number with indels (n_alt) and total (n_tot). for (s = 0; s < n; ++s) { int na = 0, nt = 0; for (i = 0; i < n_plp[s]; ++i) { const bam_pileup1_t *p = plp[s] + i; ++nt; if (p->indel != 0) { ++na; aux[m++] = MINUS_CONST + p->indel; } // FIXME: cache me in pileup struct. j = bam_cigar2qlen(p->b->core.n_cigar, bam_get_cigar(p->b)); if (j > max_rd_len) max_rd_len = j; } double frac = (double)na/nt; if ( !indel_support_ok && na >= bca->min_support && frac >= bca->min_frac ) indel_support_ok = 1; if ( na > bca->max_support && frac > 0 ) bca->max_support = na, bca->max_frac = frac; n_alt += na; n_tot += nt; } // Sort aux[] and dedup ks_introsort(uint32_t, m, aux); for (i = 1, n_types = 1; i < m; ++i) if (aux[i] != aux[i-1]) ++n_types; // Taking totals makes it hard to call rare indels (IMF filter) if ( !bca->per_sample_flt ) indel_support_ok = ( (double)n_alt / n_tot < bca->min_frac || n_alt < bca->min_support ) ? 0 : 1; if ( n_types == 1 || !indel_support_ok ) { // then skip free(aux); return NULL; } // Bail out if we have far too many types of indel if (n_types >= MAX_TYPES) { free(aux); // TODO revisit how/whether to control printing this warning if (hts_verbose >= 2) fprintf(stderr, "[%s] excessive INDEL alleles at position %d. " "Skip the position.\n", __func__, pos + 1); return NULL; } // To prevent long stretches of N's to be mistaken for indels // (sometimes thousands of bases), check the number of N's in the // sequence and skip places where half or more reference bases are Ns. int nN=0, i_end = pos + (2*bca->indel_win_size < max_rd_len ?2*bca->indel_win_size : max_rd_len); for (i=pos; i(i-pos) ) { free(aux); return NULL; } // Finally fill out the types[] array detailing the size of insertion // or deletion. types = (int*)calloc(n_types, sizeof(int)); if (!types) { free(aux); return NULL; } t = 0; for (i = 0; i < m; ++i) { int sz = (int32_t)(aux[i] - MINUS_CONST); int j; for (j = i+1; j < m; j++) if (aux[j] != aux[i]) break; if (sz == 0 || (j-i >= bca->min_support && // Note, doesn't handle bca->per_sample_flt yet (bca->per_sample_flt || (double)(j-i) / n_tot >= bca->min_frac))) types[t++] = sz; i = j-1; } free(aux); if (t <= 1) { free(types); return NULL; } n_types = t; // Find reference type; types[?] == 0) for (t = 0; t < n_types; ++t) if (types[t] == 0) break; *ref_type_r = t; *n_types_r = n_types; *max_rd_len_r = max_rd_len; *N_r = N; return types; } // Increment ins["str"] and freq["str"] #define NI 100 // number of alternative insertion sequences // Could use a hash table too, but expectation is a tiny number of alternatives typedef struct { char *str[NI]; int len[NI]; int freq[NI]; } str_freq; static int bcf_cgp_append_cons(str_freq *sf, char *str, int len, int freq) { int j; for (j = 0; j < NI && sf->str[j]; j++) { if (sf->len[j] == len && memcmp(sf->str[j], str, len) == 0) break; } if (j >= NI) return 0; // too many choices; discard sf->freq[j]+=freq; if (!sf->str[j]) { // new insertion if (!(sf->str[j] = malloc(len+1))) return -1; memcpy(sf->str[j], str, len); sf->len[j] = len; } return 0; } /* * Compute the consensus for a specific indel type at pos. * * left_shift is the number of inserted(+) or deleted(-) bases added to * the consensus before we get to pos. This is necessary so the alignment * band is correct as it's expected to start at left/right edges in * sync * * We accumulate into several buffers for counting base types: * cons_base - consensus of data with p->indel == type, bases or gap * ref_base - consensus of data with p->indel != type, bases or gap * cons_ins - consensus of data with p->indel == type, insertions * ref_ins - consensus of data with p->indel == type, bases or gap * * The purpose of cons_ins vs cons_base is if we have very low * coverage due to nearly all reads being another type, then we can * still get a robust consensus using the other data. If we don't * have shallow data, then we'll not use as much of ref_base as we may * have correlated variants. * * Eg: * REF: AGCTATGAGGCTGATA * SEQ: AGGTAGGAGGGTGATA (x1) * SEQ: AGCTACGAGG*TGATA (x24) * SEQ: AGCTACTAGG*TGATA (x24) * * Cons for no-del is Cs not Gs. Cannot trust it, so use N if shallow. * CON: AGCTACNAGGGTGATA * * There are still some problems in cons_ins vs ref_ins assignment. * We sometimes seem multiple similar-length insertions added at * different locations. Ideally we'd like to consider these as all * the same insertion if the size is the same and it's comparable seq. */ #define MAX_INS 8192 static char **bcf_cgp_consensus(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, int ref_len, int left, int right, int sample, int type, int biggest_del, int *left_shift, int *right_shift, int *band, int *tcon_len, int *cpos_pos, int pos_l, int pos_r) { // Map ASCII ACGTN* to 012345 static uint8_t base6[256] = { 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,5,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, //A C G *^ T 4,0,4,1,4,4,4,2, 4,4,4,4,4,4,4,4, 4,4,4,4,3,3,4,4, 4,4,4,4,4,4,4,4, 4,0,4,1,4,4,4,2, 4,4,4,4,4,4,4,4, 4,4,4,4,3,3,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4, }; // single base or del int (*cons_base)[6] = calloc(right - left + 1, sizeof(*cons_base)); // multi-base insertions str_freq *cons_ins = calloc(right - left + 1, sizeof(*cons_ins)); // non-indel ref for all reads on this sample, rather than those just // matching type. We use this for handling the case where we have a // homozygous deletion being studied, but with 1 or 2 reads misaligned // and containing a base there. // // Eg if the type[]=0 consensus is made up of a very small sample size, // which is also enriched for highly error prone data. We can use // the other reads from type[] != 0 to flesh out the consensus and // improve accuracy. int (*ref_base)[6] = calloc(right - left + 1, sizeof(*ref_base)); str_freq *ref_ins = calloc(right - left + 1, sizeof(*ref_ins)); int i, j, k, s = sample; char **cons = NULL; if (!cons_base || !cons_ins || !ref_base || !ref_ins) goto err; //-------------------------------------------------- // Accumulate sequences into cons_base and cons_ins arrays int local_band_max = 0; // maximum absolute deviation from diagonal int total_span_str = 0; int type_depth = 0; for (i = 0; i < n_plp[s]; i++) { const bam_pileup1_t *p = plp[s] + i; bam1_t *b = p->b; int x = b->core.pos; // ref coordinate int y = 0; // seq coordinate uint32_t *cigar = bam_get_cigar(b); uint8_t *seq = bam_get_seq(b); int local_band = 0; // current deviation from diagonal for (k = 0; k < b->core.n_cigar; ++k) { int op = cigar[k] & BAM_CIGAR_MASK; int len = cigar[k] >> BAM_CIGAR_SHIFT; int base; int skip_to = 0; switch(op) { case BAM_CSOFT_CLIP: y += len; break; case BAM_CMATCH: case BAM_CEQUAL: case BAM_CDIFF: { // Can short-cut this with j_start and j_end based on // x+len and left,right for (j = 0; j < len; j++, x++, y++) { if (x < left) continue; if (x >= right) break; base = bam_seqi(seq, y); if (p->indel == type) // Convert 4-bit base ambig code to 0,1,2,3,4 range cons_base[x-left][seq_nt16_int[base]]++; else if (x != pos+1) // indel being assessed question ref_base[x-left][seq_nt16_int[base]]++; } break; } case BAM_CINS: { if (x >= left && x < right) { local_band += p->indel; if (local_band_max < local_band) local_band_max = local_band; } char ins[MAX_INS]; for (j = 0; j < len; j++, y++) { if (x < left) continue; if (x >= right) break; base = bam_seqi(seq, y); if (j < MAX_INS) ins[j] = seq_nt16_int[base]; } // Insertions come before a ref match. // 5I 5M is IIIIIM M M M M events, not // {IIIII,M} M M M M choice. So we need to include the // next match in our sequence when choosing the consensus. if (x >= left && x < right) { int ilen = jindel == type /*&& x == pos+1*/) { // Assume any ins of the same size is the same ins. // (This rescues misaligned insertions.) if (bcf_cgp_append_cons(&cons_ins[x-left], ins, ilen, 1) < 0) goto err; type_depth += (x == pos+1); } else if (x != pos+1){ if (bcf_cgp_append_cons(&ref_ins[x-left], ins, ilen, 1) < 0) goto err; } } break; } case BAM_CDEL: if (x >= left && x < right) { local_band += p->indel; if (local_band_max < -local_band) local_band_max = -local_band; } // Maybe not perfect for I/D combos, but likely sufficient. for (j = 0; j < len; j++, x++) { if (x < left) continue; if (x >= right) break; if ((p->indel == type && !p->is_del) || // starts here (p->indel == 0 && p->is_del && len == -type)) { // left cons_base[x-left][5]++; type_depth += (x == pos+1); } else if (x+len <= pos+1 || (skip_to && x > skip_to)) ref_base[x-left][5]++; else if (x <= pos && x+len > pos+1) { // we have a deletion which overlaps pos, but // isn't the same "type". We don't wish to // include these as they may bias the // evaluation by confirming against a // secondary consensus produced with the other // deletion. We set a marker for how long to // skip adding to ref_base. if (x > skip_to) skip_to = x+len; } } break; } } if (b->core.pos <= pos_l && x >= pos_r) total_span_str++; // Also track the biggest deviation +/- from diagonal. We use // this band observation in our BAQ alignment step. if (*band < local_band_max) *band = local_band_max; } //-------------------------------------------------- // Expand cons_base to include depth from ref_base/ref_ins // Caveat: except at pos itself, where true ref is used if type != 0 #if 1 // TEST 1 // We could retest this heuristic further maybe. for (i = 0; i < right-left; i++) { // Total observed depth int t = cons_base[i][0] + cons_base[i][1] + cons_base[i][2] + cons_base[i][3] + cons_base[i][4] + cons_base[i][5]; for (j = 0; j < NI; j++) { if (!cons_ins[i].str[j]) break; t += cons_ins[i].freq[j]; } // Similarly for depth on the non-ALT calls (NB: not necessarily // REF as maybe it's other ALTs). int r = ref_base[i][0] + ref_base[i][1] + ref_base[i][2] + ref_base[i][3] + ref_base[i][4] + ref_base[i][5]; for (j = 0; j < NI; j++) { if (!ref_ins[i].str[j]) break; r += ref_ins[i].freq[j]; } // When evaluating this particular indel, we don't want to // penalise alignments by SNP errors elsewhere. This can // happen when we have low depth for a particular 'type'. // // So add in a little data from ref_base/ref_ins. double rfract = (r - t*2)*.75 / (r+1); if (rfract < 1.01 / (r+1e-10)) rfract = 1.01 / (r+1e-10); // low depth compensation // if (rfract > 0.2) // rfract = 0.2; // TODO: consider limiting rfract so we never drown out the // signal. We want to use the remaining data only to correct // for sequencing errors in low depth alleles. If we get // conflicts, it's better to use N than to change a base // incase that variant is genuine. if (i+left >= pos+1 && i+left < pos+1-biggest_del) { // We're overlapping the current indel region, so // we don't wish to bring in evidence from the other // "type" data as it'll harm calling. continue; } else { // Otherwise add in a portion of other data to // boost low population numbers. cons_base[i][0] += rfract * ref_base[i][0]; cons_base[i][1] += rfract * ref_base[i][1]; cons_base[i][2] += rfract * ref_base[i][2]; cons_base[i][3] += rfract * ref_base[i][3]; cons_base[i][4] += rfract * ref_base[i][4]; cons_base[i][5] += rfract * ref_base[i][5]; } // Similarly for insertions too; consider a different rfract here? for (j = 0; j < NI; j++) { if (!ref_ins[i].str[j]) break; if (bcf_cgp_append_cons(&cons_ins[i], ref_ins[i].str[j], ref_ins[i].len[j], rfract * ref_ins[i].freq[j]) < 0) goto err; } } #endif //-------------------------------------------------- // Allocate consensus buffer, to worst case length int max_len = right-left; for (i = 0; i < right-left; i++) { if (!cons_ins[i].str[0]) continue; int ins = 0; for (j = 0; j < NI; j++) { if (!cons_ins[i].str[j]) break; if (cons_ins[i].str[j] && ins < cons_ins[i].len[j]) ins = cons_ins[i].len[j]; } max_len += ins; } max_len += MAX(0, type); // incase type inserted bases never occur cons = malloc((max_len+1)*2 + sizeof(char *)*2); if (!cons) goto err; cons[0] = (char *)&cons[2]; cons[1] = cons[0] + max_len+1; //-------------------------------------------------- // Merge insertions where they are the same length but different // sequences. // NB: we could just index by length and have accumulators for each, // instead of storing separately and merging later (here). // Ie str_freq.str is [NI][5] instead. for (i = 0; i < right-left; i++) { int ins[MAX_INS][5]; for (j = 0; j < NI; j++) { if (!cons_ins[i].str[j]) break; if (cons_ins[i].freq[j] == 0) continue; // already merged int l; for (l = 0; l < cons_ins[i].len[j]; l++) { // Append to relevant frequency counter, zero all others ins[l][0] = ins[l][1] = ins[l][2] = ins[l][3] = ins[l][4] = 0; uint8_t b = cons_ins[i].str[j][l]; ins[l][b] = cons_ins[i].freq[j]; } // Merge other insertions of the same length to ins[] counters for (k = j+1; k < NI; k++) { if (!cons_ins[i].str[k]) break; if (cons_ins[i].len[k] != cons_ins[i].len[j]) continue; if (cons_ins[i].freq[k] == 0) continue; // redundant? // Merge str[j] and str[k] for (l = 0; l < cons_ins[i].len[k]; l++) { uint8_t b = cons_ins[i].str[k][l]; ins[l][b] += cons_ins[i].freq[k]; } cons_ins[i].freq[j] += cons_ins[i].freq[k]; cons_ins[i].freq[k] = 0; } // Now replace ins[j] with the consensus insertion of this len. for (l = 0; l < cons_ins[i].len[j]; l++) { int max_v = 0, base = 0; int tot = ins[l][0] + ins[l][1] + ins[l][2] + ins[l][3] + ins[l][4]; if (max_v < ins[l][0]) max_v = ins[l][0], base = 0; if (max_v < ins[l][1]) max_v = ins[l][1], base = 1; if (max_v < ins[l][2]) max_v = ins[l][2], base = 2; if (max_v < ins[l][3]) max_v = ins[l][3], base = 3; if (max_v < ins[l][4]) max_v = ins[l][4], base = 4; cons_ins[i].str[j][l] = (max_v > 0.6*tot) ? base : 4; } } } #define CONS_CUTOFF .40 // % needed for base vs N #define CONS_CUTOFF_DEL .35 // % to include any het del #define CONS_CUTOFF2 .80 // % needed for gap in cons[1] #define CONS_CUTOFF_INC .35 // % to include any insertion cons[0] #define CONS_CUTOFF_INC2 .80 // % to include any insertion cons[1] HOM #define CONS_CUTOFF_INS .60 // and then 60% needed for it to be bases vs N //-------------------------------------------------- // Walk through the frequency arrays to call the consensus. // We produce cons[0] and cons[1]. Both include strongly // homozygous indels. Both also include the indel at 'pos'. // However for heterozygous indels we call the most likely event // for cons[0] and the less-likely alternative in cons[1]. // TODO: a proper phase analysis so multiple events end up // combining together into the correct consensus. *left_shift = 0; *right_shift = 0; int cnum; // Het call filled out in cnum==0 (+ve or -ve). // Used in cnum==1 to do the opposite of whichever way we did before. int heti[MAX_INS] = {0}, hetd[MAX_INS] = {0}; *cpos_pos = -1; for (cnum = 0; cnum < 2; cnum++) { for (i = k = 0; i < right-left; i++) { // Location in consensus matching the indel itself if (i >= pos-left+1 && *cpos_pos == -1) *cpos_pos = k; int max_v = 0, max_v2 = 0, max_j = 4, max_j2 = 4, tot = 0; for (j = 0; j < 6; j++) { // Top 2 consensus calls if (max_v < cons_base[i][j]) { max_v2 = max_v, max_j2 = max_j; max_v = cons_base[i][j], max_j = j; } else if (max_v2 < cons_base[i][j]) { max_v2 = cons_base[i][j], max_j2 = j; } tot += cons_base[i][j]; } // +INS int max_v_ins = 0, max_j_ins = 0; int tot_ins = 0; for (j = 0; j < NI; j++) { if (i+left==pos+1) if (type > 0 && i+left == pos+1 && cons_ins[i].len[j] < type && j == 0) { cons_ins[i].str[j] = realloc(cons_ins[i].str[j], type); if (!cons_ins[i].str[j]) goto err; memset(cons_ins[i].str[j] + cons_ins[i].len[j], 4, type - cons_ins[i].len[j]); cons_ins[i].len[j] = type; } if (!cons_ins[i].str[j]) break; if (cons_ins[i].freq[j] == 0) continue; // previously merged if (max_v_ins < cons_ins[i].freq[j]) //if (i != pos-left+1 || cons_ins[i].len[j] == type) max_v_ins = cons_ins[i].freq[j], max_j_ins = j; tot_ins += cons_ins[i].freq[j]; } // NB: tot is based on next matching base, so it includes // everything with or without the insertion. int tot_sum = tot; int always_ins = (i == pos-left+1 && type>0) || // current eval max_v_ins > CONS_CUTOFF_INC2*tot_sum;// HOM int het_ins = 0; if (!always_ins && max_v_ins >= bca->min_support) { // Candidate HET ins. if (cnum == 0) { het_ins = max_v_ins > CONS_CUTOFF_INC * tot_sum; if (i < MAX_INS) heti[i] = het_ins ? 1 : (max_v_ins > .3*tot_sum ? -1:0); } else { // HET but uncalled before het_ins = i < MAX_INS ? (heti[i] == -1) : 0; } } if (always_ins || het_ins) { if (max_v_ins > CONS_CUTOFF_INS*tot_ins) { // Insert bases for (j = 0; j < cons_ins[i].len[max_j_ins]; j++) { if (cnum == 0) { if (k < pos-left+*left_shift) (*left_shift)++; else (*right_shift)++; } cons[cnum][k++] = cons_ins[i].str[max_j_ins][j]; } } else { for (j = 0; j < cons_ins[i].len[max_j_ins]; j++) cons[cnum][k++] = 4; // 'N'; } } // Call deletions & bases int always_del = (type < 0 && i > pos-left && i <= pos-left-type) || cons_base[i][5] > CONS_CUTOFF2 * tot; // HOM del int het_del = 0; if (!always_del && cons_base[i][5] >= bca->min_support) { // Candidate HET del. if (cnum == 0) { int tot2 = tot; if (i > pos-left && i <= pos-left-biggest_del) tot2 = total_span_str - type_depth; het_del = cons_base[i][5] >= CONS_CUTOFF_DEL * tot2; if (i < MAX_INS) { if (i > pos-left && i <= pos-left-biggest_del) hetd[i] = 0; else hetd[i] = het_del ? 1 : (cons_base[i][5] >= .3 * tot2 ? -1 : 0); } } else { // HET del uncalled on cnum 0 het_del = i < MAX_INS ? (hetd[i] == -1) : 0; if (max_j == 5 && het_del == 0) { max_v = max_v2; max_j = max_j2; } } } if (always_del || het_del) { // Deletion if (k < pos-left+*left_shift) (*left_shift)--; else (*right_shift)++; } else { // Finally the easy case - a non-indel base or an N if (max_v > CONS_CUTOFF*tot) cons[cnum][k++] = max_j; // "ACGTN*" else if (max_v > 0) cons[cnum][k++] = 4; // 'N'; else { cons[cnum][k] = left+k < ref_len ? base6[(uint8_t)ref[left+k]] : 4; k++; } } } tcon_len[cnum] = k; } // TODO: replace by io_lib's string pool for rapid tidying. // For now this isn't the bottleneck though. for (i = 0; i < right-left; i++) { for (j = 0; j < NI; j++) { if (cons_ins[i].str[j]) free(cons_ins[i].str[j]); if (ref_ins[i].str[j]) free(ref_ins[i].str[j]); } } err: free(cons_base); free(ref_base); free(cons_ins); free(ref_ins); return cons; } // A rename of bcf_cgp_calc_cons from bam2bcf_indel.c // // Compute the insertion consensus for this sample 's' via a basic // majority rule. // // TODO: merge this into bcf_cgp_consensus as another return value? static char *bcf_cgp_calc_ins_cons(int n, int *n_plp, bam_pileup1_t **plp, int pos, int *types, int n_types, int max_ins, int s) { return bcf_cgp_calc_cons(n, n_plp, plp, pos, types, n_types, max_ins, s); } #define MAX(a,b) ((a)>(b)?(a):(b)) #define MIN(a,b) ((a)<(b)?(a):(b)) // Compile with LIBS="-L. -ldl -ledlib" CLD=g++ // This is faster than ksw and BAQ, meaning we can use larger --indel-size and // get a more accurate context, improving alignments further. This *may* // compensate for reduced sensitivity. #include "edlib.h" int edlib_glocal(uint8_t *ref, int l_ref, uint8_t *query, int l_query, double m, double del_bias) { EdlibAlignConfig cfg = edlibNewAlignConfig( //ABS(type)+ABS(l_ref-l_query)+10, -1, // k; use small positive for faster alignment EDLIB_MODE_HW, // mode #ifdef ALIGN_DEBUG EDLIB_TASK_PATH, #else EDLIB_TASK_LOC, #endif NULL, // additionalEqualities 0); // additionalEqualitiesLength EdlibAlignResult r = edlibAlign((char *)query, l_query, (char *)ref, l_ref, cfg); if (r.status != EDLIB_STATUS_OK || r.numLocations < 1 || !r.endLocations || !r.startLocations) { edlibFreeAlignResult(r); return INT_MAX; } #ifdef ALIGN_DEBUG // NB: Needs linking against the C++ libedlib.a as our cut-down C // implementation misses the alignment generation code. { int i, j = 0, pt = r.startLocations[0], pq = 0; char line1[80]; char line2[80]; char line3[80]; for (i = 0; i < r.alignmentLength && pt < r.endLocations[0]; i++) { int n; switch (n = r.alignment[i]) { case 0: // match case 3: // mismatch line1[j] = "ACGTN"[ref[pt++]]; line2[j] = "ACGTN"[query[pq++]]; line3[j] = " x"[n==3]; break; case 2: // insertion to ref line1[j] = "ACGTN"[ref[pt++]]; line2[j] = '-'; line3[j] = '-'; break; case 1: // insertion to query line1[j] = '-'; line2[j] = "ACGTN"[query[pq++]]; line3[j] = '+'; break; } if (++j == sizeof(line1)) { fprintf(stderr, "%.*s\n", j, line1); fprintf(stderr, "%.*s\n", j, line2); fprintf(stderr, "%.*s\n", j, line3); j = 0; } } if (j) { fprintf(stderr, "%.*s\n", j, line1); fprintf(stderr, "%.*s\n", j, line2); fprintf(stderr, "%.*s\n", j, line3); } } #endif // Aligned target length minus query length is an indication of the number // of insertions and/or deletions. // // For CIGAR 10M1I10M t_len > l_query ("AC" / "ATC") // For CIGAR 10M1D10M t_len < l_query ("ATC" / "AC") // Hence t_len-l_query is -ve for net insertions and +ve for net deletions. // If we compute nins and ndel directly via walking though EDLIB_TASK_PATH // we'll see t_len-l_query == ndel-nins. // // If a technology has a significantly higher chance of making deletion // errors than insertion errors, then we would view deletions as less // indicative of this sequence not coming from this candidate allele than // if it had insertion (as the deletions are more likely to be errors // rather than real, relative to the insertions). Hence we can skew the // score by the net delta of num_del - num_ins. // // Note this is an approximation that doesn't account for multiple // insertions and deletions within the same sequence, but it is much faster // as it doesn't require EDLIB_TASK_PATH to be computed. // // Given editDistance is +1 for every mismatch, insertion and deletion, // provided the t_len-l_query multiplier < 1 then this is always +ve. int t_len = *r.endLocations - *r.startLocations + 1; int score = m*(r.editDistance - del_bias*(t_len - l_query)); edlibFreeAlignResult(r); return score; } // Part of bcf_call_gap_prep. // // Realign using BAQ to get an alignment score of a single read vs // a haplotype consensus. TODO: replace BAQ with something more robust. // // There are many coordinates, so let's explain them. // - left, right, tbeg, tend, r_start and r_end are in aligned reference // coordinates. // left/right start from pos +/- indel_win_size. // r_start/r_end are the BAM first and last mapped coord on the reference. // tbeg and tend are the intersection of the two. // - qbeg and qend are in BAM sequence coordinates // - qpos is in sequence coordinates, relative to qbeg. // // To see what this means, we have illustrations with coordinates // above the seqs in reference space and below the seqs in BAM seq space. // // Overlap left: // tbeg tend // r_start left pos r_end right // REF :..............|--------------------#------:--------------|... // SEQ :..............|--------------------#------| // 0 qbeg qpos qend // // Overlap right: // r_start tend // left tbeg pos right r_end // REF ...|--------------:-----#---------------------|...........: // SEQ |-----#---------------------|...........: // qbeg qpos qend // 0 // // The "-" sequence is the bit passed in. // Ie ref2 spans left..right and query spans qbeg..qend. // We need to adjust ref2 therefore to tbeg..tend. // // Fills out score // Returns 0 on success, // <0 on error static int bcf_cgp_align_score(bam_pileup1_t *p, bcf_callaux_t *bca, int type, int band, uint8_t *ref1, uint8_t *ref2, uint8_t *query, int r_start, int r_end, int tbeg, int tend1, int tend2, int left, int right, int qbeg, int qend, int pos, int qpos, int max_deletion, double qavg, double del_bias, int *score, int *str_len1_p, int *str_len2_p) { int atype = abs(type); int l, sc1, sc2; // Trim poly_Ns at ends of ref. // This helps to keep len(ref) and len(query) similar, to reduce // band size and reduce the chance of -ve BAQ scores. for (l = 0; l < tend1-tbeg && l < tend2-tbeg; l++) if (ref1[l + tbeg-left] != 4 || ref2[l + tbeg-left] != 4) break; if (l > atype) tbeg += l-atype; for (l = tend1-tbeg-1; l >= 0; l--) if (ref1[l + tbeg-left] != 4) break; l = tend1-tbeg-1 - l; if (l > atype) tend1 -= l-atype; for (l = tend2-tbeg-1; l >= 0; l--) if (ref2[l + tbeg-left] != 4) break; l = tend2-tbeg-1 - l; if (l > atype) { tend2 -= l-atype; } // The bottom 8 bits are length-normalised score while // the top bits are unnormalised. // // Try original cons and new cons and pick best. // This doesn't reduce FN much (infact maybe adds very slightly), // but it does reduce GT errors and is a slight reduction to FP. double mm = 30; // a const average qual for now. Could tune sc2 = edlib_glocal(ref2 + tbeg - left, tend2 - tbeg, query, qend - qbeg, mm, del_bias); if (tend1 != tend2 || memcmp((char *)ref1 + tbeg - left, (char *)ref2 + tbeg - left, tend1 - tbeg) != 0) sc1 = edlib_glocal(ref1 + tbeg - left, tend1 - tbeg, query, qend - qbeg, mm, del_bias); else sc1 = INT_MAX; // skip // Find the best of the two alignments if (sc1 < 0 && sc2 < 0) { *score = 0xffffff; return 0; } if (sc1 < 0) { // sc2 is already correct } else if (sc2 < 0) { sc2 = sc1; } else { // sc1 and sc2 both pass, so use best if (sc2 > sc1) sc2 = sc1; } // Sc is overall alignment score, in top 24 bits (SeqQ). It's based // purely on the scores for the whole alignment. // We also have a separate indel score in bottom 8 bits (IndelQ). // This is a function of all sorts of attributes of the candidate indel // itself, such as STR length and the presence of poor quality bases. // Used for adjusting indelQ below. Lower l is more likely to call // (--FN, ++FP). (NB CLI --indel_bias is 1/indel_bias var). // Starts as average score per base, and then adjusted based on seq // complexity / quality. l = .5*(100. * sc2 / (qend - qbeg) + .499); *score = (sc2<<8) | (int)MIN(255, l * bca->indel_bias * .5); return 0; } // Part of bcf_call_gap_prep. // // Returns n_alt on success // -1 on failure // TODO: almost identical to bam2bcf_indel.c's copy, so we could share // the code and add a check on bca->edlib. static int bcf_cgp_compute_indelQ(int n, int *n_plp, bam_pileup1_t **plp, bcf_callaux_t *bca, char *inscns, int l_run, int max_ins, int ref_type, int *types, int n_types, double qavg, int *score, int str_len1, int str_len2) { // FIXME: n_types has a maximum; no need to alloc - use a #define? int sc[MAX_TYPES], sumq[MAX_TYPES], s, i, j, t, K, n_alt, tmp; memset(sumq, 0, n_types * sizeof(int)); int sum_indelQ1[100] = {0}; // n int sum_indelQ2[100] = {0}; // n // Confusing variable naming and bit usage. // // score[] is low 8 bits normalised (by len) alignment score // top 24 bits full alignment score // This gets cast into "sct"; mnemonic score-per-indel-type. // // sc = (score<<6) | type (index to types[] array for indel size) // So sc>>14 = score>>(14-6) = score>>8. Ie full alignment score for (s = K = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i, ++K) { bam_pileup1_t *p = plp[s] + i; // Labelling is confusing here. // sct is short for score. // sc is score + t(type) // Why aren't these variable names reversed? int *sct = &score[K*n_types], seqQ, indelQ1=0, indelQ2=0, indelQ=0; for (t = 0; t < n_types; ++t) sc[t] = sct[t]<<6 | t; for (t = 1; t < n_types; ++t) // insertion sort for (j = t; j > 0 && sc[j] < sc[j-1]; --j) tmp = sc[j], sc[j] = sc[j-1], sc[j-1] = tmp; #ifdef ALIGN_DEBUG fprintf(stderr, "READ %s\tscores ", bam_get_qname(p->b)); for (t = 0; t < n_types; ++t) { fprintf(stderr, "%+2d/%-3d ", types[sc[t]&0x3f], sc[t]>>14); } #endif /* errmod_cal() assumes that if the call is wrong, the * likelihoods of other events are equal. This is about * right for substitutions, but is not desired for * indels. To reuse errmod_cal(), I have to make * compromise for multi-allelic indels. */ if ((sc[0]&0x3f) == ref_type) { // sc >> 14 is the total score. It's been shifted by 8 // from normalised score and 6 from type. // &0x3f is type number // Best call is REF. Compare vs best indel indelQ = (sc[1]>>14) - (sc[0]>>14); seqQ = est_seqQ(bca, types[sc[1]&0x3f], l_run, str_len1); } else { // look for the reference type for (t = 0; t < n_types; ++t) { if ((sc[t]&0x3f) == ref_type) break; } indelQ = indelQ1 = (sc[t]>>14) - (sc[0]>>14); // fprintf(stderr, "IndelQ = %d: %d-%d", // indelQ, (sc[t]>>14), (sc[0]>>14)); // Best call is non-ref, compare vs next best non-ref, // or ref if it's just 2 choices (most common case). for (t = 1; t < n_types; t++) if ((sc[t]&0x3f) == ref_type) continue; else break; if (t == n_types) t--; // it's ref, but it'll do as next best. indelQ2 = (sc[t]>>14) - (sc[0]>>14); seqQ = est_seqQ(bca, types[sc[0]&0x3f], l_run, str_len1); #if 1 // TEST 3 indelQ = bca->vs_ref*indelQ1 + (1-bca->vs_ref)*indelQ2; #endif } // So we lower qual in some, but raise the average to keep FN/FP // ratios up. // Is this key diff for PacBio old vs new HiFi? indelQ /= bca->indel_bias*0.5; indelQ1 /= bca->indel_bias*0.5; // Or maybe just *2 if bca->poly_mqual and be done with it? // Or perhaps adjust the MIN(qavg/20, ...) to MIN(qavg/10) ? // Skew SeqQ and IndelQ based on a portion of the minimum quality // found within a homopolymer. This is useful where the quality // values are a bit mutable and move around in such data, but less // so on clocked sequencing technologies. // // Enabling this causes lots of GT errors on Illumina. // However on PacBio it's key to removal of false positives. // ONT and UG seem somewhere inbetween. if (bca->poly_mqual) { // TEST 4 int qpos = p->qpos, l; uint8_t *seq = bam_get_seq(p->b); uint8_t *qual = bam_get_qual(p->b); int min_q = qual[qpos]; // scan homopolymer left char baseL = bam_seqi(seq, qpos+1 < p->b->core.l_qseq ? qpos+1 : qpos); for (l = qpos; l >= 0; l--) { if (bam_seqi(seq, l) != baseL) break; if (min_q > qual[l]) min_q = qual[l]; } // scan homo-polymer right (including site of indel) char base = bam_seqi(seq, qpos+1); for (l = qpos+1; l < p->b->core.l_qseq; l++) { if (min_q > qual[l]) min_q = qual[l]; if (bam_seqi(seq, l) != base) break; } // We reduce -h so homopolymers get reduced likelihood of being // called, but then optionally increase or decrease from there // based on base quality. Hence lack of low quality bases in // homopolymer will rescue the score back again, reducing FNs. // The score factors here may also be machine specific, but for // now these work well (tuned on PB HiFi). seqQ += MIN(qavg/20, min_q - qavg/10); indelQ += MIN(qavg/20, min_q - qavg/5); indelQ1+= MIN(qavg/20, min_q - qavg/5); if (seqQ < 0) seqQ = 0; if (indelQ < 0) indelQ = 0; if (indelQ1< 0) indelQ1= 0; } // This is the length-normalised score from bcf_cgp_align_score tmp = sc[0]>>6 & 0xff; // reduce indelQ // high score = bad, low score = good; flip for indelQ // low normalised scores leave indelQ unmodified // high normalised scores set indelQ to 0 // inbetween scores have a linear scale from indelQ to 0 // Altering the MAGIC value below (originally 111, but chosen for unknown // reasons) is comparable to altering --indel-bias. #define TMP_MAGIC 255.0 indelQ = tmp > TMP_MAGIC? 0 : (int)((1. - tmp/TMP_MAGIC) * indelQ + .499); indelQ1= tmp > TMP_MAGIC? 0 : (int)((1. - tmp/TMP_MAGIC) * indelQ1+ .499); indelQ = MIN(indelQ, 255); indelQ1 = MIN(indelQ1, 255); // Doesn't really help accuracy, but permits -h to take // affect still. if (indelQ > seqQ) indelQ = seqQ; if (indelQ > 255) indelQ = 255; if (indelQ1> 255) indelQ1= 255; if (seqQ > 255) seqQ = 255; // Use 22 bits in total. // 0-7 IndelQ // 8-15 SeqQ // 16-22 Score-per-base p->aux = (sc[0]&0x3f)<<16 | seqQ<<8 | indelQ; sumq[sc[0]&0x3f] += indelQ; #ifdef ALIGN_DEBUG fprintf(stderr, "\t%d\t%d\n", indelQ, seqQ); #endif // Experiment in p->aux vs sumq. // One gives likelihood of an indel being here, while the other // is likelihood of a specific genotype? But which is which? sum_indelQ1[s] += indelQ1; sum_indelQ2[s] += indelQ; } } // Determine bca->indel_types[] and bca->inscns. // Sumq[0] is always reference. // Sumq[1] is best non-ref (and maybe better than ref) bca->maxins = max_ins; bca->inscns = (char*) realloc(bca->inscns, bca->maxins * 4); if (bca->maxins && !bca->inscns) return -1; for (t = 0; t < n_types; ++t) sumq[t] = sumq[t]<<6 | t; for (t = 1; t < n_types; ++t) // insertion sort for (j = t; j > 0 && sumq[j] > sumq[j-1]; --j) tmp = sumq[j], sumq[j] = sumq[j-1], sumq[j-1] = tmp; for (t = 0; t < n_types; ++t) // look for the reference type if ((sumq[t]&0x3f) == ref_type) break; if (t) { // then move the reference type to the first tmp = sumq[t]; for (; t > 0; --t) sumq[t] = sumq[t-1]; sumq[0] = tmp; } for (t = 0; t < 4; ++t) bca->indel_types[t] = B2B_INDEL_NULL; for (t = 0; t < 4 && t < n_types; ++t) { bca->indel_types[t] = types[sumq[t]&0x3f]; #ifdef ALIGN_DEBUG fprintf(stderr, "TYPE %+2d %d\n", types[t], sumq[t]>>6); #endif if (bca->maxins) // potentially an insertion memcpy(&bca->inscns[t * bca->maxins], &inscns[(sumq[t]&0x3f) * max_ins], bca->maxins); } // Update p->aux. // If per-alignment type isn't found, then indelQ/seqQ is 0, // otherwise unchanged. for (s = n_alt = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i) { bam_pileup1_t *p = plp[s] + i; int x = types[p->aux>>16&0x3f]; for (j = 0; j < 4; ++j) if (x == bca->indel_types[j]) break; p->aux = j<<16 | (j == 4? 0 : (p->aux&0xffff)); if ((p->aux>>16&0x3f) > 0) ++n_alt; #ifdef ALIGN_DEBUG fprintf(stderr, "FIN %s\t%d\t%d\t%d\n", bam_get_qname(p->b), (p->aux>>16)&0x3f, bca->indel_types[(p->aux>>16)&0x3f], p->aux&0xff); #endif } } return n_alt; } /* FIXME: with high number of samples, do we handle IMF correctly? Is it fraction of indels across entire data set, or just fraction for this specific sample? Needs to check bca->per_sample_flt (--per-sample-mF) opt. */ /* notes: - n .. number of samples - the routine sets bam_pileup1_t.aux of each read as follows: - 6: unused - 6: the call; index to bcf_callaux_t.indel_types .. (aux>>16)&0x3f - 8: estimated sequence quality .. (aux>>8)&0xff - 8: indel quality .. aux&0xff */ int bcf_edlib_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, int ref_len) { if (ref == 0 || bca == 0) return -1; int i, s, t, n_types, *types = NULL, max_rd_len, left, right, max_ins; int *score = NULL; int N, K, l_run, ref_type, n_alt = -1; char *inscns = NULL, *query = NULL; // determine if there is a gap for (s = N = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i) if (plp[s][i].indel != 0) break; if (i < n_plp[s]) break; } if (s == n) // there is no indel at this position. return -1; // Find average base quality over this region double qavg = 30, qsum = 0, qcount = 0; int qmax = 0; for (s = 0; s < n; s++) { for (i = 0; i < n_plp[s]; i++) { #define QWIN 50 bam_pileup1_t *p = plp[s] + i; int kstart = p->qpos - QWIN > 0 ? p->qpos - QWIN : 0; int kend = p->qpos + QWIN < p->b->core.l_qseq ? p->qpos + QWIN : p->b->core.l_qseq; uint8_t *qual = bam_get_qual(p->b); int k; for (k = kstart; k < kend; k++) { qsum += qual[k]; qcount++; if (qmax < qual[k]) qmax = qual[k]; } } } qavg = (qsum+1) / (qcount+1); // find out how many types of indels are present types = bcf_cgp_find_types(n, n_plp, plp, pos, bca, ref, &max_rd_len, &n_types, &ref_type, &N); if (!types) goto err; // calculate left and right boundary, based on type size for a bit more // speed. int max_indel = 20*MAX(ABS(types[0]), ABS(types[n_types-1])) + bca->indel_win_size/4; if (max_indel > bca->indel_win_size) max_indel = bca->indel_win_size; left = pos > max_indel ? pos - max_indel : 0; right = pos + max_indel; int del_size = types[0]<0 ? -types[0] : 0; right += del_size; // in case the alignments stand out the reference for (i = pos; i < right; ++i) if (ref[i] == 0) break; right = i; // compute the likelihood given each type of indel for each read max_ins = types[n_types - 1]; // max_ins is at least 0 // The length of the homopolymer run around the current position l_run = bcf_cgp_l_run(ref, pos); int l_run_base = seq_nt16_table[(uint8_t)ref[pos+1]]; int l_run_ins = 0; // construct the consensus sequence (minus indels, which are added later) if (max_ins > 0) { // TODO: replace filling inscns[] with calc_consensus return // so the merges of the insertion consensus for type[t] is // reported directly. (It may need adjustment to avoid N) inscns = bcf_cgp_calc_ins_cons(n, n_plp, plp, pos, types, n_types, max_ins, s); if (!inscns) return -1; } query = (char*) calloc(right - left + max_rd_len + max_ins + 2, 1); score = (int*) calloc(N * n_types, sizeof(int)); bca->indelreg = 0; double nqual_over_60 = bca->nqual / 60.0; int biggest_del = 0; int biggest_ins = 0; for (t = 0; t < n_types; t++) { if (biggest_del > types[t]) biggest_del = types[t]; if (biggest_ins < types[t]) biggest_ins = types[t]; } int band = biggest_ins - biggest_del; // NB del is -ve // Find left & right extents of STR covering pos, from ref int pos_l = pos, pos_r = pos; { rep_ele *reps, *elt, *tmp; int pstart = MAX(0, pos-30); int pmid = pos-pstart; int pend = MIN(ref_len, pos+30); reps = find_STR((char *)&ref[pstart], pend-pstart, 0); DL_FOREACH_SAFE(reps, elt, tmp) { if (elt->end >= pmid && elt->start <= pmid) { if (pos_l > pstart + elt->start) pos_l = pstart + elt->start; if (pos_r < pstart + elt->end) pos_r = pstart + elt->end; } DL_DELETE(reps, elt); free(elt); } } int str_len1 = l_run, str_len2 = l_run/4; for (t = 0; t < n_types; ++t) { int l, ir; // Compute indelreg. This is the context in the reference. Eg: // // REF: AG--TTTC Inscns is "TT". // SEQ: AGTTTTTC Indelreg is 3; next 3 "TTT" bases // // => GTTT GTTTTT is call. if (types[t] == 0) ir = 0; else if (types[t] > 0) ir = est_indelreg(pos, ref, types[t], &inscns[t*max_ins]); else ir = est_indelreg(pos, ref, -types[t], 0); if (ir > bca->indelreg) bca->indelreg = ir; // Realignment score, computed via BAQ for (s = K = 0; s < n; ++s) { char **tcons; int left_shift, right_shift; int tcon_len[2]; int cpos_pos; tcons = bcf_cgp_consensus(n, n_plp, plp, pos, bca, ref, ref_len, left, right, s, types[t], biggest_del, &left_shift, &right_shift, &band, tcon_len, &cpos_pos, pos_l, pos_r); // TODO: Consensus for a deletion shouldn't match the // consensus for type 0. Eg consider // vv vv // REF: AATGTGTGAACAA REF: AATGTG--AACAA // T0: AATGTG--AACAA T0: AATGTG--AACAA // T-2: AA--TGTGAATAA T-2: AA--TGTGAATAA: // // On left: both T0 and T-2 are the same length, as it's // just a deletion that moved. We may end up assigning // reads to an indel allele based on the SNP they have and // not the actual indel. // There *is* a deletion here though, but only 1. How do // we call it once only? Need to replace entire region // with a reassembly. // // On right: T0 and T-2 have same length again, but there // isn't an indel as it's ins+del vs del+ins. They're // also the same length as the REF for this region. // Hence likelihood of this variant existing is tied in // with their equal and high similarity with/to the ref. // // We could do an alignment of tcons[0] and tcons[1] and check // whether their differences are consistent with (ie the // hamming distance is at least ABS(types[t]/2). I don't think // it'll rescue many FPs though. #ifdef CONS_DEBUG { int j; for (j = 0; j < 2; j++) { int k; fprintf(stderr, "Cons%d @ %d %4d/%4d ", j, pos, types[t], left_shift); for (k = 0; k < tcon_len[j]; k++) { if (k == cpos_pos) putc('#', stderr); putc("ACGTN"[(uint8_t)tcons[j][k]], stderr); } putc('\n', stderr); } } #endif // Scan for base-runs in the insertion. // We use this to avoid over-correction in est_seqQ when the // insertion is not part of the neighbouring homopolymer. int k = tcons[0][cpos_pos], j; for (j = 0; j < types[t]; j++) if (tcons[0][cpos_pos+j] != k) break; if (j && j == types[t]) l_run_ins |= "\x1\x2\x4\x8\xf"[k]; // ACGTN if (types[t] < 0) l_run_ins |= 0xff; // align each read to consensus(es) for (i = 0; i < n_plp[s]; ++i, ++K) { bam_pileup1_t *p = plp[s] + i; // Some basic ref vs alt stats. int imq = p->b->core.qual > 59 ? 59 : p->b->core.qual; imq *= nqual_over_60; int sc_len, slen, epos, sc_end; // Only need to gather stats on one type, as it's // identical calculation for all the subsequent ones // and we're sharing the same stats array if (t == 0) { // Gather stats for INFO field to aid filtering. // mq and sc_len not very helpful for filtering, but could // help in assigning a better QUAL value. // // Pos is slightly useful. // Base qual can be useful, but need qual prior to BAQ? // May need to cache orig quals in aux tag so we can fetch // them even after mpileup step. get_pos(bca, p, &sc_len, &slen, &epos, &sc_end); assert(imq >= 0 && imq < bca->nqual); assert(epos >= 0 && epos < bca->npos); assert(sc_len >= 0 && sc_len < 100); if (p->indel) { bca->ialt_mq[imq]++; bca->ialt_scl[sc_len]++; bca->ialt_pos[epos]++; } else { bca->iref_mq[imq]++; bca->iref_scl[sc_len]++; bca->iref_pos[epos]++; } } int qbeg, qpos, qend, tbeg, tend, kk; uint8_t *seq = bam_get_seq(p->b); uint32_t *cigar = bam_get_cigar(p->b); if (p->b->core.flag & BAM_FUNMAP) continue; // FIXME: the following loop should be better moved outside; // nonetheless, realignment should be much slower anyway. for (kk = 0; kk < p->b->core.n_cigar; ++kk) if ((cigar[kk]&BAM_CIGAR_MASK) == BAM_CREF_SKIP) break; if (kk < p->b->core.n_cigar) continue; // determine the start and end of sequences for alignment int left2 = left, right2 = right; int min_win_size = MAX(-biggest_del, biggest_ins); min_win_size += ABS(left_shift) + ABS(right_shift); { rep_ele *reps, *elt, *tmp; reps = find_STR(tcons[0], tcon_len[0], 0); //int max_str = 0; int tot_str = 0; DL_FOREACH_SAFE(reps, elt, tmp) { // if (max_str < elt->end - elt->start) // max_str = elt->end - elt->start; tot_str += elt->end - elt->start; DL_DELETE(reps, elt); free(elt); } // Ideally max_str should be enough, but it's still not // sufficient in longer range some repeats. //min_win_size += max_str; min_win_size += tot_str; } min_win_size += 10; // TEST 8 if (p->b->core.l_qseq > 1000) { // long read data needs less context. It also tends to // have many more candidate indels to investigate so // speed here matters more. if (pos - left >= min_win_size) left2 = MAX(left2, pos - min_win_size); if (right-pos >= min_win_size) right2 = MIN(right2, pos + min_win_size); } // Genomic coords for first and last base of query // alignment. This is only used in bcf_cgp_align_score // for computing scores by looking for the proximity // of STRs with the end of the query alignment. int r_start = p->b->core.pos; int r_end = bam_cigar2rlen(p->b->core.n_cigar, bam_get_cigar(p->b)); r_end += -1 + r_start; // Map left2/right2 genomic coordinates to qbeg/qend // query coordinates. The query may not span the // entire left/right region, so this also returns the // equivalent genomic coords for qbeg/qend in tbeg/tend. qbeg = tpos2qpos(&p->b->core, bam_get_cigar(p->b), left2, 0, &tbeg); qpos = tpos2qpos(&p->b->core, bam_get_cigar(p->b), pos, 0, &tend) - qbeg; qend = tpos2qpos(&p->b->core, bam_get_cigar(p->b), right2, 1, &tend); int old_tend = tend; int old_tbeg = tbeg; // write the query sequence for (l = qbeg; l < qend; ++l) query[l - qbeg] = seq_nt16_int[bam_seqi(seq, l)]; // tbeg and tend are the genomic locations equivalent // to qbeg and qend on the sequence. // These may being entirely within our left/right // coordinates over which we've computed the // consensus, or overlapping to left/right. // // We know an estimation of band, plus biggest indel, // so we can trim tbeg/tend to a smaller region if we // wish here. This speeds up BAQ scoring. int wband = band + MAX(-biggest_del, biggest_ins)*2 + 20; int tend1 = left + tcon_len[0] - (left2-left); int tend2 = left + tcon_len[1] - (left2-left); tend1 = MIN(tend1, old_tend + wband); tend2 = MIN(tend2, old_tend + wband); tbeg = MAX(left2, old_tbeg - wband); // do realignment; this is the bottleneck. // // Note low score = good, high score = bad. if (tend1 > tbeg && tend2 > tbeg) { //fprintf(stderr, "Num %d\n", i); if (bcf_cgp_align_score(p, bca, types[t], band, (uint8_t *)tcons[0] + left2-left, (uint8_t *)tcons[1] + left2-left, (uint8_t *)query, r_start, r_end, tbeg, tend1, tend2, left2, left + tcon_len[0], qbeg, qend, pos,qpos, -biggest_del, qavg, bca->del_bias, &score[K*n_types + t], &str_len1, &str_len2) < 0) { goto err; } #ifdef ALIGN_DEBUG fprintf(stderr, "type %d %x / %x\t%s\n", types[t], score[K*n_types + t] >> 8, score[K*n_types + t] & 0xff, bam_get_qname(p->b)); #endif } else { // place holder large cost for reads that cover the // region entirely within a deletion (thus tend < tbeg). score[K*n_types + t] = 0xffffff; } } free(tcons); } } // compute indelQ if (!(l_run_base & l_run_ins)) l_run = 1; // different base type in ins to flanking region. n_alt = bcf_cgp_compute_indelQ(n, n_plp, plp, bca, inscns, l_run, max_ins, ref_type, types, n_types, qavg, score, str_len1, str_len2); err: // free free(query); free(score); free(types); free(inscns); return n_alt > 0? 0 : -1; } bcftools-1.21/bam2bcf_iaux.c000066400000000000000000000673731467060157400157700ustar00rootroot00000000000000/* bam2bcf_iaux.c -- modified indel caller Copyright (C) 2022 Genome Research Ltd. Author: pd3@sanger, jkb Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE */ #include #include #include #include #include #include #include #include "bcftools.h" #include "bam2bcf.h" #include "read_consensus.h" #include "cigar_state.h" #include KSORT_INIT_STATIC_GENERIC(uint32_t) #ifndef DEBUG_ALN #define DEBUG_ALN 0 #endif #define MAX_TYPES 64 typedef struct { int pos; // current position char *chr; // current chromosome int nsmpl; // number of samples int *nplp; // per-sample number of reads bam_pileup1_t **plp; // per-sample reads bcf_callaux_t *bca; // auxiliary bam2bcf structure const char *ref; // reference genome (ASCII) uint32_t *uitmp; // temporary unsigned int array char *inscns; // insertions consensus "ACGTN"[itype*max_ins_len+i] int muitmp, minscns; // size of uitmp, inscns int iref_type, ntypes, types[MAX_TYPES]; // indel types int max_ins_len; // largest insertion int left, right; // consensus sequence boundaries, 0-based fa ref coordinates read_cns_t *rcns; // read consensus cns_seq_t *cns_seq; // array of consensus sequences int *cns_pos; // array of relative pos indexes within cns_seq sequences uint8_t *ref_seq, *qry_seq; // reference and query sequence to align int nref_seq, nqry_seq; // the allocated size of ref_seq and qry_seq uint8_t *qual; int nqual; int *read_scores, // read scores for each indel type [ntypes*iread+itype] mread_scores, ref_qual[MAX_TYPES], // refseq quality at pos for each indel type in the context of homopolymer runs sum_qual[MAX_TYPES]; // qual contributions to each indel type from all reads } indel_aux_t; #if DEBUG_ALN static void debug_print_types(indel_aux_t *iaux) { int i,j; fprintf(stderr,"types at %s:%d ntypes=%d... ",iaux->chr,iaux->pos+1,iaux->ntypes); for (i=0; intypes; i++) { fprintf(stderr," type%d=",i); if ( iaux->types[i]<=0 ) { if ( i==iaux->iref_type ) fprintf(stderr,"%d(ref)",iaux->types[i]); else fprintf(stderr,"%d",iaux->types[i]); continue; } char *cns = &iaux->inscns[i*iaux->max_ins_len]; for (j=0; jtypes[i]; j++) fprintf(stderr,"%c","ACGTN"[(int)cns[j]]); } fprintf(stderr,"\n"); } #else #define debug_print_types(iaux) #endif void bcf_iaux_destroy(bcf_callaux_t *bca) { if ( !bca->iaux ) return; indel_aux_t *iaux = (indel_aux_t*)bca->iaux; free(iaux->uitmp); free(iaux->inscns); free(iaux->ref_seq); free(iaux->qry_seq); free(iaux->qual); free(iaux->read_scores); rcns_destroy(iaux->rcns); free(iaux); } static void iaux_init_sequence_context(indel_aux_t *iaux) { // Calculate left and right boundary. The array types is sorted in ascending order, the first // element is the largest deletion (if a deletion present) iaux->left = iaux->pos > iaux->bca->indel_win_size ? iaux->pos - iaux->bca->indel_win_size : 0; iaux->right = iaux->pos + iaux->bca->indel_win_size; if ( iaux->types[0] < 0 ) iaux->right -= iaux->types[0]; // extend by the largest deletion length // In case the alignments stand out the reference int i; for (i=iaux->pos; iright; i++) if ( !iaux->ref[i] ) break; iaux->right = i; // Sequence quality in the context of homopolymers for each indel type int l_run = bcf_cgp_l_run(iaux->ref, iaux->pos); // The length of the homopolymer run around the current position for (i=0; intypes; i++) { int l = iaux->types[i]; // This is the original est_seqQ() code. FIXME: check if the inserted sequence is consistent with the homopolymer run int q = iaux->bca->openQ + iaux->bca->extQ * (abs(l) - 1); int qh = l_run >= 3? (int)(iaux->bca->tandemQ * (double)abs(l) / l_run + .499) : 1000; if ( q > qh ) q = qh; iaux->ref_qual[i] = q < 255 ? q : 255; } // Determine the indel region, this makes the difference between e.g. T>TA vs TA>TAA iaux->bca->indelreg = 0; for (i=0; intypes; i++) { if ( !iaux->types[i] ) continue; int ireg; if ( iaux->types[i] > 0 ) ireg = est_indelreg(iaux->pos, iaux->ref, iaux->types[i], &iaux->inscns[i*iaux->max_ins_len]); else ireg = est_indelreg(iaux->pos, iaux->ref, -iaux->types[i], 0); if ( ireg > iaux->bca->indelreg ) iaux->bca->indelreg = ireg; } } static int iaux_init_scores(indel_aux_t *iaux, int ismpl) { int n = iaux->nplp[ismpl] * iaux->ntypes; if ( iaux->mread_scores < n ) { int *tmp = (int*) realloc(iaux->read_scores,n*sizeof(int)); if ( !tmp ) return -1; iaux->mread_scores = n; iaux->read_scores = tmp; } memset(iaux->read_scores,0,n); return 0; } static int _have_indel_reads(indel_aux_t *iaux) { int i,j; for (i=0; insmpl; i++) { for (j=0; jnplp[i]; j++) if ( iaux->plp[i][j].indel ) return 1; } return 0; } // For insertions only their sizes were collected so far. Now go through the reads and // create consensus sequence for each insert, therefore note that there can be only one // sequence per insertion length static int iaux_init_ins_types(indel_aux_t *iaux) { if ( !iaux->max_ins_len ) return 0; uint32_t *aux; int naux = 5 * iaux->ntypes * iaux->max_ins_len; if ( iaux->muitmp < naux ) { aux = (uint32_t*) realloc(iaux->uitmp,naux*sizeof(*aux)); if ( !aux ) return -1; iaux->uitmp = aux; iaux->muitmp = naux; } else aux = iaux->uitmp; memset(aux,0,naux*sizeof(*aux)); // count the number of occurrences of each base at each position for each type of insertion int t,s,i,j; for (t=0; tntypes; t++) { if ( iaux->types[t] <= 0) continue; for (s=0; snsmpl; s++) { for (i=0; inplp[s]; i++) { bam_pileup1_t *plp = iaux->plp[s] + i; if ( plp->indel != iaux->types[t] ) continue; uint8_t *seq = bam_get_seq(plp->b); for (j=0; jindel; j++) { int c = seq_nt16_int[bam_seqi(seq, plp->qpos+j+1)]; assert(c<5); aux[5*(t*iaux->max_ins_len+j) + c]++; } } } } char *cns; int ncns = iaux->ntypes * iaux->max_ins_len; if ( iaux->minscns < ncns ) { cns = (char*) realloc(iaux->inscns,naux*sizeof(*aux)); if ( !cns ) return -1; iaux->inscns = cns; iaux->minscns = ncns; } else cns = iaux->inscns; memset(aux,0,ncns*sizeof(*cns)); // use the majority rule to construct the consensus for (t=0; tntypes; t++) { for (i=0; itypes[t]; i++) // this naturally includes only insertions { uint32_t *tmp = &aux[5*(t*iaux->max_ins_len+i)], max = tmp[0], max_j = 0; for (j=1; j<5; j++) if ( max < tmp[j] ) max = tmp[j], max_j = j; cns[t*iaux->max_ins_len + i] = max ? max_j : 4; if ( max_j==4 ) { iaux->types[t] = 0; break; } // discard insertions which contain N's } } return 0; } #define MINUS_CONST 0x10000000 static int iaux_init_types(indel_aux_t *iaux) { if ( !_have_indel_reads(iaux) ) return 0; iaux->bca->max_support = 0; memset(iaux->sum_qual,0,MAX_TYPES*sizeof(*iaux->sum_qual)); int i,j, nreads = 0; for (i=0; insmpl; i++) nreads += iaux->nplp[i]; uint32_t *aux; if ( iaux->muitmp < nreads+1 ) { aux = (uint32_t*) realloc(iaux->uitmp,(nreads+1)*sizeof(*iaux->uitmp)); if ( !aux ) return -1; iaux->uitmp = aux; iaux->muitmp = nreads+1; } else aux = iaux->uitmp; memset(aux,0,(nreads+1)*sizeof(*aux)); int naux = 0, indel_support_ok = 0, n_alt = 0, n_tot = 0; int max_rd_len = 0; // max sequence length that includes ref+del bases // Fill out aux[] array with all the non-zero indel sizes. This is an unsorted list with as many // entries as there are reads aux[naux++] = MINUS_CONST; // zero indel is always a type (REF) for (i=0; insmpl; i++) { int nalt = naux, ntot = 0; // per sample values for (j=0; jnplp[i]; j++) { const bam_pileup1_t *plp = iaux->plp[i] + j; ntot++; if ( plp->indel ) aux[naux++] = MINUS_CONST + plp->indel; if ( !PLP_QLEN(&plp->cd) ) PLP_QLEN(&plp->cd) = bam_cigar2qlen(plp->b->core.n_cigar, bam_get_cigar(plp->b)); if ( PLP_QLEN(&plp->cd) > max_rd_len ) max_rd_len = PLP_QLEN(&plp->cd); } nalt = naux - nalt; if ( iaux->bca->per_sample_flt ) { double frac = (double)nalt/naux; if ( nalt >= iaux->bca->min_support && frac >= iaux->bca->min_frac ) indel_support_ok = 1; if ( nalt > iaux->bca->max_support && frac > 0 ) iaux->bca->max_support = nalt, iaux->bca->max_frac = frac; } else { n_alt += nalt; n_tot += ntot; } } // Check if the minimum required number of indel reads has been observed if ( !iaux->bca->per_sample_flt && n_alt >= iaux->bca->min_support && (double)n_alt/n_tot >= iaux->bca->min_frac ) indel_support_ok = 1; if ( naux==1 || !indel_support_ok ) return 0; // To prevent long stretches of N's to be mistaken for indels (sometimes thousands of bases), check the number of N's in the // sequence and skip places where half or more reference bases in the sequence that follows pos are Ns int nN = 0, i_end = iaux->pos + (iaux->bca->indel_win_size < max_rd_len ? iaux->bca->indel_win_size : max_rd_len); for (i=iaux->pos; iref[i]; i++) if ( iaux->ref[i] == 'N' ) nN++; if ( 2*nN > i - iaux->pos ) return -1; // Sort aux[] and dedup indel types int n_types = 1; ks_introsort(uint32_t, naux, aux); for (i=1; i= MAX_TYPES ) { static int warned = 0; if ( !warned ) { fprintf(stderr, "Warning: excessive number of INDEL alleles at %s:%d, skipping. (This warning is printed only once)\n",iaux->chr,iaux->pos+1); warned = 1; } return -1; } // Fill out the types[] array detailing the size of insertion or deletion. iaux->ntypes = 0; iaux->max_ins_len = 0; for (i=0; iiref_type = iaux->ntypes; } else { if ( j-i >= iaux->bca->min_support ) is_ok = 1; // What is the best way to handle the -pmF options: // - consider only sites where a single indel type passes the -mF threshold, as opposed to all indel types cumulatively // - once a site passes, include all indel types in the evaluation, as opposed to considering only the strong candidates // In this implementation sites are selected by counting reads from all indel types cumulatively and all indel types // are considered. // Uncomment the following condition to consider only strong indel candidates once the site has been selected // if ( !iaux->bca->per_sample_flt && (double)(j-i) / n_tot < iaux->bca->min_frac ) is_ok = 0; } if ( is_ok ) { iaux->types[iaux->ntypes++] = isize; if ( isize > 0 && isize > iaux->max_ins_len ) iaux->max_ins_len = isize; } i = j-1; } if ( iaux->ntypes <= 1 ) return 0; // Init insertion types, including their sequence if ( iaux_init_ins_types(iaux) < 0 ) return -1; iaux_init_sequence_context(iaux); return iaux->ntypes; } #undef MINUS_CONST static int iaux_set_consensus(indel_aux_t *iaux, int ismpl) { if ( !iaux->rcns ) iaux->rcns = rcns_init(iaux->pos, iaux->left, iaux->right); else rcns_reset(iaux->rcns, iaux->pos, iaux->left, iaux->right); rcns_set_reads(iaux->rcns, iaux->plp[ismpl], iaux->nplp[ismpl]); iaux->cns_seq = rcns_get_consensus(iaux->rcns, iaux->ref + iaux->left); // todo: // rcns should also collect localized number of mismatches as a substitute // for uninformative MQ. This would not affect calling but would help with // filtering return 0; } #if 0 // Finds the smallest index in the seq_pos array holding value equal to pos, or if there is no // such value, the largest index with value smaller than pos. Starts at initial guess ioff. // This could use a binary search but the assumption is that the initial guess is indel-size close // to the actual coordinate. // // TODO: remove this function and seq_pos from cns creation as it seems unnecessary static int find_ref_offset(hts_pos_t pos, hts_pos_t *seq_pos, int nseq_pos, int ioff) { if ( ioff<0 ) ioff = 0; else if ( ioff >= nseq_pos ) ioff = nseq_pos - 1; if ( seq_pos[ioff] < pos ) { while ( ioff+1 < nseq_pos && seq_pos[ioff] < pos ) ioff++; if ( seq_pos[ioff] > pos ) ioff--; return ioff; } while ( ioff > 0 && seq_pos[ioff-1] >= pos ) ioff--; return ioff; } #endif static int iaux_align_read(indel_aux_t *iaux, bam1_t *bam, uint8_t *ref_seq, int nref_seq) { if ( bam->core.flag & BAM_FUNMAP ) return 1; // skip unmapped reads // Trim both ref and qry to the window of interest hts_pos_t ref_beg = iaux->left; // fa ref coordinates hts_pos_t ref_end = iaux->right < ref_beg + nref_seq ? iaux->right : ref_beg + nref_seq - 1; cigar_state_t cigar; cstate_init(&cigar,bam); int qry_off1, qry_off2, ref_off1, ref_off2; if ( ref_beg > bam->core.pos ) { // the read needs trimming from left qry_off1 = cstate_seek_fwd(&cigar, &ref_beg, 1); ref_off1 = ref_beg - iaux->left; if ( ref_beg + (bam->core.l_qseq - qry_off1) > ref_end ) { // the read needs trimming from right qry_off2 = ref_end - ref_beg + qry_off1; ref_off2 = ref_end - iaux->left; } else { // the ref template needs trimming from right qry_off2 = bam->core.l_qseq - 1; ref_off2 = ref_off1 + qry_off2 - qry_off1; } } else { // the ref template needs trimming from left qry_off1 = 0; ref_off1 = bam->core.pos - ref_beg; if ( bam->core.pos + bam->core.l_qseq - 1 > ref_end ) { // the read needs trimming from right ref_off2 = ref_end - iaux->left; qry_off2 = ref_off2 - ref_off1; } else { // the ref template needs trimming from right qry_off2 = bam->core.l_qseq - 1; ref_off2 = ref_off1 + qry_off2 - qry_off1; } } //fprintf(stderr,"xtrim: %s .. left,right=%d,%d rbeg,end=%d,%d qpos=%d qlen=%d qoff=%d,%d roff=%d,%d rlen=%d\n",bam_get_qname(bam),iaux->left,iaux->right,(int)ref_beg,(int)ref_end,(int)bam->core.pos,bam->core.l_qseq, qry_off1,qry_off2,ref_off1,ref_off2,nref_seq); assert( qry_off1<=qry_off2 ); assert( qry_off1>=0 && qry_off1core.l_qseq ); assert( qry_off2>=0 && qry_off2core.l_qseq ); assert( ref_off1<=ref_off2 ); assert( ref_off1>=0 && ref_off1=0 && ref_off2nqry_seq < qlen ) { uint8_t *tmp = (uint8_t*) realloc(iaux->qry_seq, qlen); if ( !tmp ) return -1; // critical error iaux->qry_seq = tmp; iaux->nqry_seq = qlen; } uint8_t *seq = bam_get_seq(bam); for (i=qry_off1; i<=qry_off2; i++) iaux->qry_seq[i-qry_off1] = seq_nt16_int[bam_seqi(seq,i)]; // prepare qualities, either BQ or BAQ qualities (ZQ) if ( iaux->nqual < qlen ) { uint8_t *tmp = (uint8_t*) realloc(iaux->qual, qlen); if ( !tmp ) return -1; // critical error iaux->qual = tmp; iaux->nqual = qlen; } uint8_t *qual = iaux->qual; const uint8_t *qq = bam_get_qual(bam); const uint8_t *bq = (uint8_t*)bam_aux_get(bam, "ZQ"); if ( bq ) bq++; // skip type for (i=qry_off1; i<=qry_off2; i++) { int j = i - qry_off1; qual[j] = bq ? qq[i] + (bq[i] - 64) : qq[i]; if ( qual[j] > 30 ) qual[j] = 30; if ( qual[j] < 7 ) qual[j] = 7; } // Illumina probaln_par_t apf = { 1e-4, 1e-2, 10 }; // align int score = probaln_glocal(ref_seq + ref_off1, rlen, iaux->qry_seq, qlen, qual, &apf, 0, 0); int adj_score = (int)(100. * score / qlen + .499) * iaux->bca->indel_bias; #if DEBUG_ALN fprintf(stderr,"aln: %d/%d\t%s\n\tref: ",score,adj_score,bam_get_qname(bam)); for (i=0; iqry_seq[i]]); fprintf(stderr,"\n\tqual: "); for (i=0; i 255 ) adj_score = 255; return score<<8 | adj_score; } // Score all reads for this sample and indel type using the up to two consensus sequence templates. // On output sets iaux->read_scores[iread*ntypes+itype] = (raw_score<<8 | length_adjusted_score) static int iaux_score_reads(indel_aux_t *iaux, int ismpl, int itype) { int i; cns_seq_t *cns = iaux->cns_seq; while ( cns->nseq ) { // Resize buffers if necessary int ref_len = cns->nseq + iaux->types[itype]; if ( iaux->nref_seq < ref_len ) { uint8_t *ref_buf = (uint8_t*) realloc(iaux->ref_seq,sizeof(uint8_t)*ref_len); if ( !ref_buf ) return -1; iaux->ref_seq = ref_buf; iaux->nref_seq = ref_len; } // Apply the indel and create the template ref sequence... memcpy(iaux->ref_seq,cns->seq,(cns->ipos+1)*sizeof(*iaux->ref_seq)); if ( iaux->types[itype] < 0 ) // deletion memcpy(iaux->ref_seq + cns->ipos + 1, cns->seq + cns->ipos + 1 - iaux->types[itype], (cns->nseq - cns->ipos - 1 + iaux->types[itype])*sizeof(*iaux->ref_seq)); else { char *ins = &iaux->inscns[itype*iaux->max_ins_len]; for (i=0; itypes[itype]; i++) iaux->ref_seq[cns->ipos+1+i] = ins[i]; memcpy(iaux->ref_seq + cns->ipos + 1 + iaux->types[itype], cns->seq + 1 + cns->ipos, (cns->nseq - cns->ipos - 1)*sizeof(*iaux->ref_seq)); } #if DEBUG_ALN fprintf(stderr,"template %d, type %d, sample %d: ",cns==iaux->cns_seq?0:1,itype,ismpl); for (i=0; iref_seq[i]]); fprintf(stderr,"\n"); #endif // Align and score reads for (i=0; inplp[ismpl]; i++) { const bam_pileup1_t *plp = iaux->plp[ismpl] + i; int aln_score = iaux_align_read(iaux, plp->b, iaux->ref_seq, ref_len); int *score = &iaux->read_scores[i*iaux->ntypes+itype]; if ( cns==iaux->cns_seq || *score > aln_score ) *score = aln_score; } cns++; } return 0; } // Determines indel quality for each read and populates 22 bits of pileup aux field with // three integers as follows // plp->aux = indel_type << 16 | seqQ << 8 | indelQ static int iaux_eval_scored_reads(indel_aux_t *iaux, int ismpl) { int i,j; for (i=0; inplp[ismpl]; i++) { bam_pileup1_t *plp = iaux->plp[ismpl] + i; // Find the best indel type and the ref type, their scores difference is the indel quality int *score = &iaux->read_scores[i*iaux->ntypes]; int alt_score = INT_MAX, alt_j = 0; for (j=0; jiref_type; j++) if ( alt_score > score[j] ) alt_score = score[j], alt_j = j; for (j=iaux->iref_type+1; jntypes; j++) if ( alt_score > score[j] ) alt_score = score[j], alt_j = j; int ref_score = score[iaux->iref_type]; int sc0, sc1, j0; if ( alt_score < ref_score ) sc0 = alt_score, sc1 = ref_score, j0 = alt_j; else sc0 = ref_score, sc1 = alt_score, j0 = iaux->iref_type; int indelQ = (sc1>>8) - (sc0>>8); // low=bad, high=good int seqQ = iaux->ref_qual[alt_j]; // Reduce indelQ. High length-normalized alignment scores (i.e. bad alignments) // lower the quality more (e.g. gnuplot> plot [0:111] (1-x/111.)*255) int len_normQ = sc0 & 0xff; // length-normalized score of the best match (ref or alt) int adj_indelQ; // final indelQ used in calling if ( len_normQ > 111 ) { // In the original code reads matching badly to any indel type or reference had indelQ set to 0 // here and thus would be effectively removed from calling. This leads to problems when there are // many soft clipped reads and a few good matching indel reads (see noisy-softclips.bam in // mpileup-tests). Only the few good quality indel reads would become visible to the caller and // the indel would be called with high quality. Here we change the logic to make the badly matching // reads low quality reference reads. The threshold was set to make the test case still be called // as an indel, but with very low quality. // // Original code: // adj_indelQ = 0; // adj_indelQ = 12; j0 = iaux->iref_type; } else adj_indelQ = (int)((1. - len_normQ/111.) * indelQ + .499); #if DEBUG_ALN // Prints the selected indel type (itype); adjusted indelQ which will be used if bigger than seqQ; // raw indelQ; length-normalized indelQ and sequence context quality; ref and best alt indel type // and their raw and length-normalized scores fprintf(stderr,"itype=%d adj_indelQ=%d\trawQ=%d\tlen_normQ=%d\tseqQ=%d\tref:%d=%d/%d alt:%d=%d/%d)\t%s\n", j0,adj_indelQ,indelQ,len_normQ,seqQ,iaux->iref_type,ref_score>>8,ref_score&0xff,alt_j,alt_score>>8,alt_score&0xff,bam_get_qname(plp->b)); #endif if ( adj_indelQ > seqQ ) adj_indelQ = seqQ; // seqQ already capped at 255 plp->aux = j0<<16 | seqQ<<8 | adj_indelQ; // use 22 bits in total iaux->sum_qual[j0] += adj_indelQ; } return 0; } // Find the best indel types, include the ref type plus maximum three alternate indel alleles. static int iaux_eval_best_indels(indel_aux_t *iaux) { bcf_callaux_t *bca = iaux->bca; bca->maxins = iaux->max_ins_len; bca->inscns = (char*) realloc(bca->inscns, bca->maxins * 4); if ( bca->maxins && !bca->inscns ) return -1; // insertion sort, descending, high-quality indels come first int i,j,t, tmp, *sumq = iaux->sum_qual, ntypes = iaux->ntypes; for (t=0; t0 && sumq[j] > sumq[j-1]; j--) tmp = sumq[j], sumq[j] = sumq[j-1], sumq[j-1] = tmp; for (t=0; tiref_type ) break; if ( t ) { // move the reference type to the first tmp = sumq[t]; for (; t>0; t--) sumq[t] = sumq[t-1]; sumq[0] = tmp; } // Initialize bca's structures and create a mapping between old and new types int old2new_type[MAX_TYPES]; for (t=0; tntypes; t++) { int itype = sumq[t] & 0x3f; old2new_type[itype] = t; if ( t>=4 ) continue; bca->indel_types[t] = iaux->types[itype]; if ( bca->indel_types[t] <= 0 ) continue; memcpy(&bca->inscns[t*bca->maxins], &iaux->inscns[itype*iaux->max_ins_len], bca->maxins); } // Update indel type in plp->aux for all reads int ismpl, n_alt = 0; for (ismpl=0; ismplnsmpl; ismpl++) { for (i=0; inplp[ismpl]; i++) { bam_pileup1_t *plp = iaux->plp[ismpl] + i; int itype_old = (plp->aux >> 16) & 0x3f; int itype_new = old2new_type[itype_old]; plp->aux = itype_new<<16 | (itype_new>=4 ? 0 : (plp->aux & 0xffff)); if ( itype_new>0 ) n_alt++; } } return n_alt; } /* notes: - n .. number of samples - the routine sets bam_pileup1_t.aux (27 bits) of each read as follows: - 5: unused - 6: the call; index to bcf_callaux_t.indel_types .. (aux>>16)&0x3f - 8: estimated sequence quality .. (aux>>8)&0xff - 8: indel quality .. aux&0xff */ int bcf_iaux_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref) { assert(!(ref == 0 || bca == 0)); // can this ever happen? when? if (ref == 0 || bca == 0) return -1; if ( !bca->iaux ) bca->iaux = calloc(1,sizeof(indel_aux_t)); indel_aux_t *iaux = bca->iaux; iaux->nsmpl = n; iaux->nplp = n_plp; iaux->plp = plp; iaux->bca = bca; iaux->ref = ref; iaux->pos = pos; iaux->chr = bca->chr; // Check if there is an indel at this position and if yes, find all indel types and determine // window boundaries. todo: We want this information cached so that for long reads we don't keep // redoing the whole analysis again and again int ntypes = iaux_init_types(iaux); if ( ntypes<=0 ) return -1; debug_print_types(iaux); // Create two template consensus sequences for each sample (assuming max diploid organism). // Then apply each indel type on top of the templates, realign every read and remember score int i,j; for (i=0; insmpl; i++) { iaux_set_consensus(iaux, i); iaux_init_scores(iaux, i); for (j=0; j 0 ? 0 : -1; } bcftools-1.21/bam2bcf_indel.c000066400000000000000000001041571467060157400161050ustar00rootroot00000000000000/* bam2bcf_indel.c -- indel caller. Copyright (C) 2010, 2011 Broad Institute. Copyright (C) 2012-2014,2016-2017, 2021 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include "bam2bcf.h" #include "str_finder.h" #include KSORT_INIT_GENERIC(uint32_t) #define MINUS_CONST 0x10000000 #define MAX_TYPES 64 // Take a reference position tpos and convert to a query position (returned). // This uses the CIGAR string plus alignment c->pos to do the mapping. // // *_tpos is returned as tpos if query overlaps tpos, but for deletions // it'll be either the start (is_left) or end (!is_left) ref position. int tpos2qpos(const bam1_core_t *c, const uint32_t *cigar, int32_t tpos, int is_left, int32_t *_tpos) { // x = pos in ref, y = pos in query seq int k, x = c->pos, y = 0, last_y = 0; *_tpos = c->pos; for (k = 0; k < c->n_cigar; ++k) { int op = cigar[k] & BAM_CIGAR_MASK; int l = cigar[k] >> BAM_CIGAR_SHIFT; if (op == BAM_CMATCH || op == BAM_CEQUAL || op == BAM_CDIFF) { if (c->pos > tpos) return y; if (x + l > tpos) { *_tpos = tpos; return y + (tpos - x); } x += l; y += l; last_y = y; } else if (op == BAM_CINS || op == BAM_CSOFT_CLIP) y += l; else if (op == BAM_CDEL || op == BAM_CREF_SKIP) { if (x + l > tpos) { *_tpos = is_left? x : x + l; return y; } x += l; } } *_tpos = x; return last_y; } // FIXME: check if the inserted sequence is consistent with the homopolymer run // l is the relative gap length and l_run is the length of the homopolymer on the reference static inline int est_seqQ(const bcf_callaux_t *bca, int l, int l_run) { int q, qh; q = bca->openQ + bca->extQ * (abs(l) - 1); qh = l_run >= 3? (int)(bca->tandemQ * (double)abs(l) / l_run + .499) : 1000; return q < qh? q : qh; } inline int est_indelreg(int pos, const char *ref, int l, char *ins4) { int i, j, max = 0, max_i = pos, score = 0; l = abs(l); for (i = pos + 1, j = 0; ref[i]; ++i, ++j) { if (ins4) score += (toupper(ref[i]) != "ACGTN"[(int)ins4[j%l]])? -10 : 1; else score += (toupper(ref[i]) != toupper(ref[pos+1+j%l]))? -10 : 1; if (score < 0) break; if (max < score) max = score, max_i = i; } return max_i - pos; } // Identify spft-clip length, position in seq, and clipped seq len void get_pos(const bcf_callaux_t *bca, bam_pileup1_t *p, int *sc_len_r, int *slen_r, int *epos_r, int *end) { bam1_t *b = p->b; int sc_len = 0, sc_dist = -1, at_left = 1; int epos = p->qpos, slen = b->core.l_qseq; int k; uint32_t *cigar = bam_get_cigar(b); *end = -1; for (k = 0; k < b->core.n_cigar; k++) { int op = bam_cigar_op(cigar[k]); if (op == BAM_CSOFT_CLIP) { slen -= bam_cigar_oplen(cigar[k]); if (at_left) { // left end sc_len += bam_cigar_oplen(cigar[k]); epos -= sc_len; // don't count SC in seq pos sc_dist = epos; *end = 0; } else { // right end int srlen = bam_cigar_oplen(cigar[k]); int rd = b->core.l_qseq - srlen - p->qpos; if (sc_dist < 0 || sc_dist > rd) { // closer to right end than left // FIXME: compensate for indel length too? sc_dist = rd; sc_len = srlen; *end = 1; } } } else if (op != BAM_CHARD_CLIP) { at_left = 0; } } if (p->indel > 0 && slen - (epos+p->indel) < epos) epos += p->indel-1; // end of insertion, if near end of seq // slen is now length of sequence minus soft-clips and // epos is position of indel in seq minus left-clip. *epos_r = (double)epos / (slen+1) * bca->npos; if (sc_len) { // scale importance of clip by distance to closest end *sc_len_r = 15.0*sc_len / (sc_dist+1); if (*sc_len_r > 99) *sc_len_r = 99; } else { *sc_len_r = 0; } *slen_r = slen; } // Part of bcf_call_gap_prep. // // Scans the pileup to identify all the different sizes of indels // present. // types[] returned is sorted by size, from smallest (maybe negative) to largest. // // Returns types and fills out n_types_r, max_rd_len_r and ref_type_r, // or NULL on error. static int *bcf_cgp_find_types(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, int *max_rd_len_r, int *n_types_r, int *ref_type_r, int *N_r) { int i, j, t, s, N, m, max_rd_len, n_types; int n_alt = 0, n_tot = 0, indel_support_ok = 0; uint32_t *aux; int *types; // N is the total number of reads for (s = N = 0; s < n; ++s) N += n_plp[s]; bca->max_support = bca->max_frac = 0; aux = (uint32_t*) calloc(N + 1, 4); if (!aux) return NULL; m = max_rd_len = 0; aux[m++] = MINUS_CONST; // zero indel is always a type (REF) // Fill out aux[] array with all the non-zero indel sizes. // Also tally number with indels (n_alt) and total (n_tot). for (s = 0; s < n; ++s) { int na = 0, nt = 0; for (i = 0; i < n_plp[s]; ++i) { const bam_pileup1_t *p = plp[s] + i; ++nt; if (p->indel != 0) { ++na; aux[m++] = MINUS_CONST + p->indel; } // FIXME: cache me in pileup struct. j = bam_cigar2qlen(p->b->core.n_cigar, bam_get_cigar(p->b)); if (j > max_rd_len) max_rd_len = j; } double frac = (double)na/nt; if ( !indel_support_ok && na >= bca->min_support && frac >= bca->min_frac ) indel_support_ok = 1; if ( na > bca->max_support && frac > 0 ) bca->max_support = na, bca->max_frac = frac; n_alt += na; n_tot += nt; } // Sort aux[] and dedup ks_introsort(uint32_t, m, aux); for (i = 1, n_types = 1; i < m; ++i) if (aux[i] != aux[i-1]) ++n_types; // Taking totals makes it hard to call rare indels (IMF filter) if ( !bca->per_sample_flt ) indel_support_ok = ( (double)n_alt / n_tot < bca->min_frac || n_alt < bca->min_support ) ? 0 : 1; if ( n_types == 1 || !indel_support_ok ) { // then skip free(aux); return NULL; } // Bail out if we have far too many types of indel if (n_types >= MAX_TYPES) { free(aux); // TODO revisit how/whether to control printing this warning if (hts_verbose >= 2) fprintf(stderr, "[%s] excessive INDEL alleles at position %d. " "Skip the position.\n", __func__, pos + 1); return NULL; } // To prevent long stretches of N's to be mistaken for indels // (sometimes thousands of bases), check the number of N's in the // sequence and skip places where half or more reference bases are Ns. int nN=0, i_end = pos + (2*bca->indel_win_size < max_rd_len ?2*bca->indel_win_size : max_rd_len); for (i=pos; i(i-pos) ) { free(aux); return NULL; } // Finally fill out the types[] array detailing the size of insertion // or deletion. types = (int*)calloc(n_types, sizeof(int)); if (!types) { free(aux); return NULL; } t = 0; types[t++] = aux[0] - MINUS_CONST; for (i = 1; i < m; ++i) if (aux[i] != aux[i-1]) types[t++] = aux[i] - MINUS_CONST; free(aux); // Find reference type; types[?] == 0) for (t = 0; t < n_types; ++t) if (types[t] == 0) break; *ref_type_r = t; *n_types_r = n_types; *max_rd_len_r = max_rd_len; *N_r = N; return types; } // Part of bcf_call_gap_prep. // // Construct per-sample consensus. // // Returns an array of consensus seqs, // or NULL on failure. static char **bcf_cgp_ref_sample(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref, int left, int right) { int i, k, s, L = right - left + 1, max_i, max2_i; char **ref_sample; // returned uint32_t *cns = NULL, max, max2; char *ref0 = NULL, *r; ref_sample = (char**) calloc(n, sizeof(char*)); cns = (uint32_t*) calloc(L, 4); ref0 = (char*) calloc(L, 1); if (!ref_sample || !cns || !ref0) { n = 0; goto err; } // Convert ref ASCII to 0-15. for (i = 0; i < right - left; ++i) ref0[i] = seq_nt16_table[(int)ref[i+left]]; // NB: one consensus per sample 'n', not per indel type. // FIXME: consider fixing this. We should compute alignments vs // types, not vs samples? Or types/sample combined? for (s = 0; s < n; ++s) { r = ref_sample[s] = (char*) calloc(L, 1); if (!r) { n = s-1; goto err; } memset(cns, 0, sizeof(int) * L); // collect ref and non-ref counts in cns for (i = 0; i < n_plp[s]; ++i) { bam_pileup1_t *p = plp[s] + i; bam1_t *b = p->b; uint32_t *cigar = bam_get_cigar(b); uint8_t *seq = bam_get_seq(b); int x = b->core.pos, y = 0; // TODO: pileup exposes pileup_ind, but we also need e.g. // pileup_len to know how much of the current CIGAR op-len // we've used (or have remaining). If we had that, we // could start at p->qpos without having to scan through // the entire CIGAR string until we find it. // // Without it about all we could do is have a side channel // to cache the last known coords. Messy, so punt for now. // This is no longer the bottle neck until we get to 1000s of // CIGAR ops. for (k = 0; k < b->core.n_cigar; ++k) { int op = cigar[k]&0xf; int j, l = cigar[k]>>4; if (op == BAM_CMATCH || op == BAM_CEQUAL || op == BAM_CDIFF) { if (x + l >= left) { j = left - x > 0 ? left - x : 0; int j_end = right - x < l ? right - x : l; for (; j < j_end; j++) // Append to cns. Note this is ref coords, // so insertions aren't in cns and deletions // will have lower coverage. // FIXME: want true consensus (with ins) per // type, so we can independently compare each // seq to each consensus and see which it // matches best, so we get proper GT analysis. cns[x+j-left] += (bam_seqi(seq, y+j) == ref0[x+j-left]) ? 1 // REF : (1<<16); // ALT } x += l; y += l; } else if (op == BAM_CDEL || op == BAM_CREF_SKIP) { x += l; } else if (op == BAM_CINS || op == BAM_CSOFT_CLIP) { y += l; } if (x > right) break; } } // Determine a sample specific reference. for (i = 0; i < right - left; ++i) r[i] = ref0[i]; // Find deepest and 2nd deepest ALT region (max & max2). max = max2 = 0; max_i = max2_i = -1; for (i = 0; i < right - left; ++i) { if (cns[i]>>16 >= max>>16) max2 = max, max2_i = max_i, max = cns[i], max_i = i; else if (cns[i]>>16 >= max2>>16) max2 = cns[i], max2_i = i; } // Masks mismatches present in at least 70% of the reads with 'N'. // This code is nREF/(nREF+n_ALT) >= 70% for deepest region. // The effect is that at least 30% of bases differing to REF will // use "N" in consensus, so we don't penalise ALT or REF when // aligning against it. (A poor man IUPAC code) // // Why is it only done in two loci at most? if ((double)(max&0xffff) / ((max&0xffff) + (max>>16)) >= 0.7) max_i = -1; if ((double)(max2&0xffff) / ((max2&0xffff) + (max2>>16)) >= 0.7) max2_i = -1; if (max_i >= 0) r[max_i] = 15; if (max2_i >= 0) r[max2_i] = 15; //for (i = 0; i < right - left; ++i) // fputc("=ACMGRSVTWYHKDBN"[(int)r[i]], stderr); //fputc('\n', stderr); } free(ref0); free(cns); return ref_sample; err: free(ref0); free(cns); if (ref_sample) { for (s = 0; s < n; s++) free(ref_sample[s]); free(ref_sample); } return NULL; } // The length of the homopolymer run around the current position int bcf_cgp_l_run(const char *ref, int pos) { int i, l_run; int c = seq_nt16_table[(int)ref[pos + 1]]; if (c == 15) { l_run = 1; } else { for (i = pos + 2; ref[i]; ++i) if (seq_nt16_table[(int)ref[i]] != c) break; l_run = i; for (i = pos; i >= 0; --i) if (seq_nt16_table[(int)ref[i]] != c) break; l_run -= i + 1; } return l_run; } // Compute the consensus for this sample 's', minus indels which // get added later. char *bcf_cgp_calc_cons(int n, int *n_plp, bam_pileup1_t **plp, int pos, int *types, int n_types, int max_ins, int s) { int i, j, t, k; int *inscns_aux = (int*)calloc(5 * n_types * max_ins, sizeof(int)); if (!inscns_aux) return NULL; // Count the number of occurrences of each base at each position for // each type of insertion. for (t = 0; t < n_types; ++t) { if (types[t] > 0) { for (s = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i) { bam_pileup1_t *p = plp[s] + i; if (p->indel == types[t]) { uint8_t *seq = bam_get_seq(p->b); for (k = 1; k <= p->indel; ++k) { int c = seq_nt16_int[bam_seqi(seq, p->qpos + k)]; assert(c<5); ++inscns_aux[(t*max_ins+(k-1))*5 + c]; } } } } } } // Use the majority rule to construct the consensus char *inscns = (char *)calloc(n_types * max_ins, 1); for (t = 0; t < n_types; ++t) { for (j = 0; j < types[t]; ++j) { int max = 0, max_k = -1, *ia = &inscns_aux[(t*max_ins+j)*5]; for (k = 0; k < 5; ++k) if (ia[k] > max) max = ia[k], max_k = k; inscns[t*max_ins + j] = max ? max_k : 4; if (max_k == 4) { // discard insertions which contain N's types[t] = 0; break; } } } free(inscns_aux); return inscns; } #ifndef MIN # define MIN(a,b) ((a)<(b)?(a):(b)) #endif // Part of bcf_call_gap_prep. // // Realign using BAQ to get an alignment score of a single read vs // a haplotype consensus. // // Fills out score // Returns 0 on success, // <0 on error static int bcf_cgp_align_score(bam_pileup1_t *p, bcf_callaux_t *bca, int type, uint8_t *ref2, uint8_t *query, int r_start, int r_end, int long_read, int tbeg, int tend, int left, int right, int qbeg, int qend, int qpos, int max_deletion, int *score) { // Illumina probaln_par_t apf = { 1e-4, 1e-2, 10 }; // Parameters that work better on PacBio CCS 15k. // We should consider querying the header and RG PU field. // See also htslib/realn.c:sam_prob_realn() if (long_read) { apf.d = 1e-3; apf.e = 1e-1; } type = abs(type); apf.bw = type + 3; int l, sc; const uint8_t *qual = bam_get_qual(p->b), *bq; uint8_t *qq; // Get segment of quality, either ZQ tag or if absent QUAL. if (!(qq = (uint8_t*) calloc(qend - qbeg, 1))) return -1; bq = (uint8_t*)bam_aux_get(p->b, "ZQ"); if (bq) ++bq; // skip type for (l = qbeg; l < qend; ++l) { int qval = bq? qual[l] + (bq[l] - 64) : qual[l]; if (qval > 30) qval = 30; if (qval < 7) qval = 7; qq[l - qbeg] = qval; } // The bottom 8 bits are length-normalised score while // the top bits are unnormalised. sc = probaln_glocal(ref2 + tbeg - left, tend - tbeg + type, query, qend - qbeg, qq, &apf, 0, 0); if (sc < 0) { *score = 0xffffff; free(qq); return 0; } // used for adjusting indelQ below l = (int)(100. * sc / (qend - qbeg) + .499) * bca->indel_bias; *score = sc<<8 | MIN(255, l); rep_ele *reps, *elt, *tmp; uint8_t *seg = ref2 + tbeg - left; int seg_len = tend - tbeg + type; // Note: although seg moves (tbeg varies), ref2 is reused many times // so we could factor out some find_STR calls. However it's not the // bottleneck for now. // FIXME: need to make this work on IUPAC. reps = find_STR((char *)seg, seg_len, 0); int iscore = 0; // Identify STRs in ref covering the indel up to // (or close to) the end of the sequence. // Those having an indel and right at the sequence // end do not confirm the total length of indel // size. Specifically a *lack* of indel at the // end, where we know indels occur in other // sequences, is a possible reference bias. // // This is emphasised further if the sequence ends with // soft clipping. DL_FOREACH_SAFE(reps, elt, tmp) { if (elt->start <= qpos && elt->end >= qpos) { iscore += (elt->end-elt->start) / elt->rep_len; // c if (elt->start+tbeg <= r_start || elt->end+tbeg >= r_end) iscore += 2*(elt->end-elt->start); } DL_DELETE(reps, elt); free(elt); } // Apply STR score to existing indelQ l = (*score&0xff)*.8 + iscore*2; *score = (*score & ~0xff) | MIN(255, l); free(qq); return 0; } // Part of bcf_call_gap_prep. // // Returns n_alt on success // -1 on failure static int bcf_cgp_compute_indelQ(int n, int *n_plp, bam_pileup1_t **plp, bcf_callaux_t *bca, char *inscns, int l_run, int max_ins, int ref_type, int *types, int n_types, int *score) { // FIXME: n_types has a maximum; no need to alloc - use a #define? int sc[MAX_TYPES], sumq[MAX_TYPES], s, i, j, t, K, n_alt, tmp; memset(sumq, 0, n_types * sizeof(int)); for (s = K = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i, ++K) { bam_pileup1_t *p = plp[s] + i; int *sct = &score[K*n_types], seqQ, indelQ; for (t = 0; t < n_types; ++t) sc[t] = sct[t]<<6 | t; for (t = 1; t < n_types; ++t) // insertion sort for (j = t; j > 0 && sc[j] < sc[j-1]; --j) tmp = sc[j], sc[j] = sc[j-1], sc[j-1] = tmp; /* errmod_cal() assumes that if the call is wrong, the * likelihoods of other events are equal. This is about * right for substitutions, but is not desired for * indels. To reuse errmod_cal(), I have to make * compromise for multi-allelic indels. */ if ((sc[0]&0x3f) == ref_type) { indelQ = (sc[1]>>14) - (sc[0]>>14); seqQ = est_seqQ(bca, types[sc[1]&0x3f], l_run); } else { for (t = 0; t < n_types; ++t) // look for the reference type if ((sc[t]&0x3f) == ref_type) break; indelQ = (sc[t]>>14) - (sc[0]>>14); seqQ = est_seqQ(bca, types[sc[0]&0x3f], l_run); } tmp = sc[0]>>6 & 0xff; // reduce indelQ indelQ = tmp > 111? 0 : (int)((1. - tmp/111.) * indelQ + .499); // Doesn't really help accuracy, but permits -h to take // affect still. if (indelQ > seqQ) indelQ = seqQ; if (indelQ > 255) indelQ = 255; if (seqQ > 255) seqQ = 255; p->aux = (sc[0]&0x3f)<<16 | seqQ<<8 | indelQ; // use 22 bits in total sumq[sc[0]&0x3f] += indelQ < seqQ? indelQ : seqQ; // fprintf(stderr, "pos=%d read=%d:%d name=%s call=%d indelQ=%d seqQ=%d\n", pos, s, i, bam1_qname(p->b), types[sc[0]&0x3f], indelQ, seqQ); } } // determine bca->indel_types[] and bca->inscns bca->maxins = max_ins; bca->inscns = (char*) realloc(bca->inscns, bca->maxins * 4); if (bca->maxins && !bca->inscns) return -1; for (t = 0; t < n_types; ++t) sumq[t] = sumq[t]<<6 | t; for (t = 1; t < n_types; ++t) // insertion sort for (j = t; j > 0 && sumq[j] > sumq[j-1]; --j) tmp = sumq[j], sumq[j] = sumq[j-1], sumq[j-1] = tmp; for (t = 0; t < n_types; ++t) // look for the reference type if ((sumq[t]&0x3f) == ref_type) break; if (t) { // then move the reference type to the first tmp = sumq[t]; for (; t > 0; --t) sumq[t] = sumq[t-1]; sumq[0] = tmp; } for (t = 0; t < 4; ++t) bca->indel_types[t] = B2B_INDEL_NULL; for (t = 0; t < 4 && t < n_types; ++t) { bca->indel_types[t] = types[sumq[t]&0x3f]; if (bca->maxins) memcpy(&bca->inscns[t * bca->maxins], &inscns[(sumq[t]&0x3f) * max_ins], bca->maxins); } // update p->aux for (s = n_alt = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i) { bam_pileup1_t *p = plp[s] + i; int x = types[p->aux>>16&0x3f]; for (j = 0; j < 4; ++j) if (x == bca->indel_types[j]) break; p->aux = j<<16 | (j == 4? 0 : (p->aux&0xffff)); if ((p->aux>>16&0x3f) > 0) ++n_alt; //fprintf(stderr, "X pos=%d read=%d:%d name=%s call=%d type=%d seqQ=%d indelQ=%d\n", pos, s, i, bam_get_qname(p->b), (p->aux>>16)&0x3f, bca->indel_types[(p->aux>>16)&0x3f], (p->aux>>8)&0xff, p->aux&0xff); } } return n_alt; } /* FIXME: with high number of samples, do we handle IMF correctly? Is it fraction of indels across entire data set, or just fraction for this specific sample? Needs to check bca->per_sample_flt (--per-sample-mF) opt. */ /* notes: - n .. number of samples - the routine sets bam_pileup1_t.aux of each read as follows: - 6: unused - 6: the call; index to bcf_callaux_t.indel_types .. (aux>>16)&0x3f - 8: estimated sequence quality .. (aux>>8)&0xff - 8: indel quality .. aux&0xff */ int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref) { if (ref == 0 || bca == 0) return -1; int i, s, j, k, t, n_types, *types, max_rd_len, left, right, max_ins; int *score, max_ref2; int N, K, l_run, ref_type, n_alt; char *inscns = 0, *ref2, *query, **ref_sample; // determine if there is a gap for (s = N = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i) if (plp[s][i].indel != 0) break; if (i < n_plp[s]) break; } if (s == n) // there is no indel at this position. return -1; // find out how many types of indels are present types = bcf_cgp_find_types(n, n_plp, plp, pos, bca, ref, &max_rd_len, &n_types, &ref_type, &N); if (!types) return -1; // calculate left and right boundary left = pos > bca->indel_win_size ? pos - bca->indel_win_size : 0; right = pos + bca->indel_win_size; if (types[0] < 0) right -= types[0]; // in case the alignments stand out the reference for (i = pos; i < right; ++i) if (ref[i] == 0) break; right = i; /* The following call fixes a long-existing flaw in the INDEL * calling model: the interference of nearby SNPs. However, it also * reduces the power because sometimes, substitutions caused by * indels are not distinguishable from true mutations. Multiple * sequence realignment helps to increase the power. * * Masks mismatches present in at least 70% of the reads with 'N'. */ ref_sample = bcf_cgp_ref_sample(n, n_plp, plp, pos, bca, ref, left, right); // The length of the homopolymer run around the current position l_run = bcf_cgp_l_run(ref, pos); // construct the consensus sequence (minus indels, which are added later) max_ins = types[n_types - 1]; // max_ins is at least 0 if (max_ins > 0) { inscns = bcf_cgp_calc_cons(n, n_plp, plp, pos, types, n_types, max_ins, s); if (!inscns) return -1; } // compute the likelihood given each type of indel for each read max_ref2 = right - left + 2 + 2 * (max_ins > -types[0]? max_ins : -types[0]); ref2 = (char*) calloc(max_ref2, 1); query = (char*) calloc(right - left + max_rd_len + max_ins + 2, 1); score = (int*) calloc(N * n_types, sizeof(int)); bca->indelreg = 0; double nqual_over_60 = bca->nqual / 60.0; for (t = 0; t < n_types; ++t) { int l, ir; // compute indelreg if (types[t] == 0) ir = 0; else if (types[t] > 0) ir = est_indelreg(pos, ref, types[t], &inscns[t*max_ins]); else ir = est_indelreg(pos, ref, -types[t], 0); if (ir > bca->indelreg) bca->indelreg = ir; // Identify max deletion length int max_deletion = 0; for (s = 0; s < n; ++s) { for (i = 0; i < n_plp[s]; ++i, ++K) { bam_pileup1_t *p = plp[s] + i; if (max_deletion < -p->indel) max_deletion = -p->indel; } } // Realignment score, computed via BAQ for (s = K = 0; s < n; ++s) { // Construct ref2 from ref_sample, inscns and indels. // This is now the true sample consensus (possibly prepended // and appended with reference if sample data doesn't span // the full length). for (k = 0, j = left; j <= pos; ++j) ref2[k++] = seq_nt16_int[(int)ref_sample[s][j-left]]; if (types[t] <= 0) j += -types[t]; else for (l = 0; l < types[t]; ++l) ref2[k++] = inscns[t*max_ins + l]; for (; j < right && ref[j]; ++j) ref2[k++] = seq_nt16_int[(int)ref_sample[s][j-left]]; for (; k < max_ref2; ++k) ref2[k] = 4; if (right > j) right = j; // align each read to ref2 for (i = 0; i < n_plp[s]; ++i, ++K) { bam_pileup1_t *p = plp[s] + i; // Some basic ref vs alt stats. int imq = p->b->core.qual > 59 ? 59 : p->b->core.qual; imq *= nqual_over_60; int sc_len, slen, epos, sc_end; // Only need to gather stats on one type, as it's // identical calculation for all the subsequent ones // and we're sharing the same stats array if (t == 0) { // Gather stats for INFO field to aid filtering. // mq and sc_len not very helpful for filtering, but could // help in assigning a better QUAL value. // // Pos is slightly useful. // Base qual can be useful, but need qual prior to BAQ? // May need to cache orig quals in aux tag so we can fetch // them even after mpileup step. get_pos(bca, p, &sc_len, &slen, &epos, &sc_end); assert(imq >= 0 && imq < bca->nqual); assert(epos >= 0 && epos < bca->npos); assert(sc_len >= 0 && sc_len < 100); if (p->indel) { bca->ialt_mq[imq]++; bca->ialt_scl[sc_len]++; bca->ialt_pos[epos]++; } else { bca->iref_mq[imq]++; bca->iref_scl[sc_len]++; bca->iref_pos[epos]++; } } int qbeg, qpos, qend, tbeg, tend, kk; uint8_t *seq = bam_get_seq(p->b); uint32_t *cigar = bam_get_cigar(p->b); if (p->b->core.flag & BAM_FUNMAP) continue; // FIXME: the following loop should be better moved outside; // nonetheless, realignment should be much slower anyway. for (kk = 0; kk < p->b->core.n_cigar; ++kk) if ((cigar[kk]&BAM_CIGAR_MASK) == BAM_CREF_SKIP) break; if (kk < p->b->core.n_cigar) continue; // determine the start and end of sequences for alignment // FIXME: loops over CIGAR multiple times int left2 = left, right2 = right; if (p->b->core.l_qseq > 1000) { // long read data needs less context. It also tends to // have many more candidate indels to investigate so // speed here matters more. if (pos - left >= bca->indel_win_size) left2 += bca->indel_win_size/2; if (right-pos >= bca->indel_win_size) right2 -= bca->indel_win_size/2; } int r_start = p->b->core.pos; int r_end = bam_cigar2rlen(p->b->core.n_cigar, bam_get_cigar(p->b)) -1 + r_start; qbeg = tpos2qpos(&p->b->core, bam_get_cigar(p->b), left2, 0, &tbeg); qpos = tpos2qpos(&p->b->core, bam_get_cigar(p->b), pos, 0, &tend) - qbeg; qend = tpos2qpos(&p->b->core, bam_get_cigar(p->b), right2, 1, &tend); if (types[t] < 0) { int l = -types[t]; tbeg = tbeg - l > left? tbeg - l : left; } // write the query sequence for (l = qbeg; l < qend; ++l) query[l - qbeg] = seq_nt16_int[bam_seqi(seq, l)]; // A fudge for now. Consider checking SAM header for // RG platform field. int long_read = p->b->core.l_qseq > 1000; // do realignment; this is the bottleneck if (tend > tbeg) { if (bcf_cgp_align_score(p, bca, types[t], (uint8_t *)ref2 + left2-left, (uint8_t *)query, r_start, r_end, long_read, tbeg, tend, left2, right2, qbeg, qend, qpos, max_deletion, &score[K*n_types + t]) < 0) { score[K*n_types + t] = 0xffffff; return -1; } } else { // place holder large cost for reads that cover the // region entirely within a deletion (thus tend < tbeg). score[K*n_types + t] = 0xffffff; } #if 0 for (l = 0; l < tend - tbeg + abs(types[t]); ++l) fputc("ACGTN"[(int)ref2[tbeg-left+l]], stderr); fputc('\n', stderr); for (l = 0; l < qend - qbeg; ++l) fputc("ACGTN"[(int)query[l]], stderr); fputc('\n', stderr); fprintf(stderr, "pos=%d type=%d read=%d:%d name=%s " "qbeg=%d tbeg=%d score=%d\n", pos, types[t], s, i, bam_get_qname(p->b), qbeg, tbeg, score[K*n_types + t]); #endif } } } // compute indelQ n_alt = bcf_cgp_compute_indelQ(n, n_plp, plp, bca, inscns, l_run, max_ins, ref_type, types, n_types, score); // free free(ref2); free(query); free(score); for (i = 0; i < n; ++i) free(ref_sample[i]); free(ref_sample); free(types); free(inscns); return n_alt > 0? 0 : -1; } bcftools-1.21/bam_sample.c000066400000000000000000000326261467060157400155370ustar00rootroot00000000000000/* bam_sample.c -- group data by sample. Copyright (C) 2010, 2011 Broad Institute. Copyright (C) 2013, 2016-2022 Genome Research Ltd. Author: Heng Li , Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include "bam_sample.h" #include "bcftools.h" typedef struct { char *fname; void *rg2idx; // hash: read group name to BCF output sample index. Maintained by bsmpl_add_readgroup int default_idx; // default BCF output sample index, set only when all readgroups are treated as one sample } file_t; struct _bam_smpl_t { kstring_t tmp; file_t *files; int ignore_rg, nsmpl, nfiles; char **smpl; // list of BCF output sample names. Maintained by bsmpl_add_readgroup void *sample_list; // hash: BAM input sample name to BCF output sample name. This is the -s/-S list int sample_logic; // the -s/-S logic, 1: include, 0: exclude void *rg_list; // hash: BAM/rg_id to sample name or */rg_id for global ids. This is the -G list int rg_logic; // the -G logic, 1: include, 0: exclude void *name2idx; // hash: BCF output sample name to BCF output sample index. Maintained by bsmpl_add_readgroup }; bam_smpl_t *bam_smpl_init(void) { bam_smpl_t *bsmpl; bsmpl = (bam_smpl_t*) calloc(1, sizeof(bam_smpl_t)); bsmpl->name2idx = khash_str2int_init(); return bsmpl; } void bam_smpl_destroy(bam_smpl_t *bsmpl) { if ( !bsmpl ) return; if ( bsmpl->name2idx ) khash_str2int_destroy_free(bsmpl->name2idx); if ( bsmpl->sample_list ) khash_str2str_destroy_free_all(bsmpl->sample_list); if ( bsmpl->rg_list ) khash_str2str_destroy_free_all(bsmpl->rg_list); int i; for (i=0; infiles; i++) { file_t *file = &bsmpl->files[i]; if ( file->rg2idx ) khash_str2int_destroy_free(file->rg2idx); free(file->fname); } free(bsmpl->smpl); free(bsmpl->files); free(bsmpl->tmp.s); free(bsmpl); } void bam_smpl_ignore_readgroups(bam_smpl_t* bsmpl) { bsmpl->ignore_rg = 1; } static void bsmpl_add_readgroup(bam_smpl_t *bsmpl, file_t *file, const char *rg_id, const char *smpl_name) { int ismpl = -1; if ( smpl_name ) { if ( khash_str2int_get(bsmpl->name2idx,smpl_name,&ismpl) < 0 ) { // new sample bsmpl->nsmpl++; bsmpl->smpl = (char**) realloc(bsmpl->smpl,sizeof(char*)*bsmpl->nsmpl); bsmpl->smpl[bsmpl->nsmpl-1] = strdup(smpl_name); ismpl = khash_str2int_inc(bsmpl->name2idx,bsmpl->smpl[bsmpl->nsmpl-1]); } } if ( !strcmp("*",rg_id) ) { // all read groups in the bam treated as the same sample file->default_idx = ismpl; return; } if ( !file->rg2idx ) file->rg2idx = khash_str2int_init(); if ( khash_str2int_has_key(file->rg2idx,rg_id) ) return; // duplicate @RG:ID khash_str2int_set(file->rg2idx, strdup(rg_id), ismpl); } static int bsmpl_keep_readgroup(bam_smpl_t *bsmpl, file_t *file, const char *rg_id, const char **smpl_name) { char *rg_smpl = khash_str2str_get(bsmpl->rg_list,rg_id); // unique read group present in one bam only if ( !rg_smpl ) { // read group specific to this bam bsmpl->tmp.l = 0; ksprintf(&bsmpl->tmp,"%s\t%s",rg_id,file->fname); rg_smpl = khash_str2str_get(bsmpl->rg_list,bsmpl->tmp.s); } if ( !rg_smpl ) { // any read group in this file? bsmpl->tmp.l = 0; ksprintf(&bsmpl->tmp,"*\t%s",file->fname); rg_smpl = khash_str2str_get(bsmpl->rg_list,bsmpl->tmp.s); } if ( !rg_smpl && bsmpl->rg_logic ) return 0; if ( rg_smpl && !bsmpl->rg_logic ) return 0; if ( rg_smpl && rg_smpl[0]!='\t' ) *smpl_name = rg_smpl; // rename the sample return 1; } /* The logic of this function is a bit complicated because we want to work also with broken bams containing read groups that are not listed in the header. The desired behavior is as follows: - when -G is given, read groups which are not listed in the header must be given explicitly using the "?" symbol in -G. Otherwise: - if the bam has no header, all reads in the file are assigned to a single sample named after the file - if there is at least one sample defined in the header, reads with no read group id or with a read group id not listed in the header are assigned to the first sample encountered in the header */ int bam_smpl_add_bam(bam_smpl_t *bsmpl, char *bam_hdr, const char *fname) { bsmpl->nfiles++; bsmpl->files = (file_t*) realloc(bsmpl->files,bsmpl->nfiles*sizeof(file_t)); file_t *file = &bsmpl->files[bsmpl->nfiles-1]; memset(file,0,sizeof(file_t)); file->fname = strdup(fname); file->default_idx = -1; if ( bsmpl->ignore_rg || !bam_hdr ) { // The option --ignore-RG is set or there is no BAM header: use the file name as the sample name bsmpl_add_readgroup(bsmpl,file,"*",file->fname); return bsmpl->nfiles-1; } void *bam_smpls = khash_str2int_init(); int first_smpl = -1, nskipped = 0; const char *p = bam_hdr, *q, *r; while (p != NULL && (q = strstr(p, "@RG")) != 0) { char *eol = strchr(q + 3, '\n'); if (q > bam_hdr && *(q - 1) != '\n') { // @RG must be at start of line p = eol; continue; } p = q + 3; if ((q = strstr(p, "\tID:")) != 0) q += 4; if ((r = strstr(p, "\tSM:")) != 0) r += 4; if (r && q) { char *u, *v; int ioq, ior; for (u = (char*)q; *u && *u != '\t' && *u != '\n'; ++u); for (v = (char*)r; *v && *v != '\t' && *v != '\n'; ++v); ioq = *u; ior = *v; *u = *v = '\0'; // q now points to a null terminated read group id // r points to a null terminated sample name if ( !strcmp("*",q) || !strcmp("?",q) ) error("Error: the read group IDs \"*\" and \"?\" have a special meaning in the mpileup code. Please fix the code or the bam: %s\n", fname); int accept_rg = 1; if ( bsmpl->sample_list ) { // restrict samples based on the -s/-S options char *name = khash_str2str_get(bsmpl->sample_list,r); if ( bsmpl->sample_logic==0 ) accept_rg = name ? 0 : 1; else if ( !name ) accept_rg = 0; else r = name; } if ( accept_rg && bsmpl->rg_list ) { // restrict readgroups based on the -G option, possibly renaming the sample accept_rg = bsmpl_keep_readgroup(bsmpl,file,q,&r); } if ( accept_rg ) bsmpl_add_readgroup(bsmpl,file,q,r); else { bsmpl_add_readgroup(bsmpl,file,q,NULL); // ignore this RG but note that it was seen in the header nskipped++; } if ( first_smpl<0 ) khash_str2int_get(bsmpl->name2idx,r,&first_smpl); if ( !khash_str2int_has_key(bam_smpls,r) ) khash_str2int_inc(bam_smpls,strdup(r)); *u = ioq; *v = ior; } else break; p = eol; } int nsmpls = khash_str2int_size(bam_smpls); khash_str2int_destroy_free(bam_smpls); const char *smpl_name = NULL; int accept_null_rg = 1; if ( bsmpl->rg_list && !bsmpl_keep_readgroup(bsmpl,file,"?",&smpl_name) ) accept_null_rg = 0; if ( bsmpl->sample_list && first_smpl==-1 ) accept_null_rg = 0; if ( !accept_null_rg && first_smpl==-1 ) { // no suitable read group is available in this bam: ignore the whole file. free(file->fname); if ( file->rg2idx ) khash_str2int_destroy_free(file->rg2idx); bsmpl->nfiles--; return -1; } if ( !accept_null_rg ) return bsmpl->nfiles-1; if ( nsmpls==1 && !nskipped ) { file->default_idx = first_smpl; return bsmpl->nfiles-1; } if ( !smpl_name ) smpl_name = first_smpl==-1 ? file->fname : bsmpl->smpl[first_smpl]; bsmpl_add_readgroup(bsmpl,file,"?",smpl_name); return bsmpl->nfiles-1; } const char **bam_smpl_get_samples(bam_smpl_t *bsmpl, int *nsmpl) { *nsmpl = bsmpl->nsmpl; return (const char**)bsmpl->smpl; } int bam_smpl_get_sample_id(bam_smpl_t *bsmpl, int bam_id, bam1_t *bam_rec) { file_t *file = &bsmpl->files[bam_id]; if ( file->default_idx >= 0 ) return file->default_idx; char *aux_rg = (char*) bam_aux_get(bam_rec, "RG"); aux_rg = aux_rg ? aux_rg+1 : "?"; int rg_id; if ( khash_str2int_get(file->rg2idx, aux_rg, &rg_id)==0 ) return rg_id; if ( khash_str2int_get(file->rg2idx, "?", &rg_id)==0 ) return rg_id; return -1; } int bam_smpl_add_samples(bam_smpl_t *bsmpl, char *list, int is_file) { if ( list[0]!='^' ) bsmpl->sample_logic = 1; else list++; int i, nsamples = 0; char **samples = hts_readlist(list, is_file, &nsamples); if ( !samples || !nsamples ) return 0; kstring_t ori = {0,0,0}; kstring_t ren = {0,0,0}; bsmpl->sample_list = khash_str2str_init(); for (i=0; isample_list,strdup(ori.s),strdup(ren.l?ren.s:ori.s)); free(samples[i]); } free(samples); free(ori.s); free(ren.s); return nsamples; } int bam_smpl_add_readgroups(bam_smpl_t *bsmpl, char *list, int is_file) { if ( list[0]!='^' ) bsmpl->rg_logic = 1; else list++; int i, nrows = 0; char **rows = hts_readlist(list, is_file, &nrows); if ( !rows || !nrows ) return 0; kstring_t fld1 = {0,0,0}; kstring_t fld2 = {0,0,0}; kstring_t fld3 = {0,0,0}; bsmpl->rg_list = khash_str2str_init(); for (i=0; irg_list,fld1.s); if ( !value ) khash_str2str_set(bsmpl->rg_list,strdup(fld1.s),strdup(fld2.l?fld2.s:"\t")); else if ( strcmp(value,fld2.l?fld2.s:"\t") ) error("Error: The read group \"%s\" was assigned to two different samples: \"%s\" and \"%s\"\n", fld1.s,value,fld2.l?fld2.s:"\t"); free(rows[i]); } free(rows); free(fld1.s); free(fld2.s); free(fld3.s); return nrows; } bcftools-1.21/bam_sample.h000066400000000000000000000037561467060157400155460ustar00rootroot00000000000000/* bam_sample.h -- group data by sample. Copyright (C) 2010 Broad Institute. Copyright (C) 2016 Genome Research Ltd. Author: Heng Li , Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef BAM_SAMPLE_H #define BAM_SAMPLE_H #include typedef struct _bam_smpl_t bam_smpl_t; bam_smpl_t *bam_smpl_init(void); int bam_smpl_add_samples(bam_smpl_t *bsmpl, char *list, int is_file); int bam_smpl_add_readgroups(bam_smpl_t *bsmpl, char *list, int is_file); void bam_smpl_ignore_readgroups(bam_smpl_t* bsmpl); // The above should be called only before bams are added. Returns the BAM id // to be passed to bam_smpl_get_sample_id() later. It is safe to assume // sequential numbering, starting from 0. // int bam_smpl_add_bam(bam_smpl_t *bsmpl, char *bam_hdr, const char *fname); const char **bam_smpl_get_samples(bam_smpl_t *bsmpl, int *nsmpl); int bam_smpl_get_sample_id(bam_smpl_t *bsmpl, int bam_id, bam1_t *bam_rec); void bam_smpl_destroy(bam_smpl_t *bsmpl); #endif bcftools-1.21/bcftools.h000066400000000000000000000147301467060157400152530ustar00rootroot00000000000000/* bcftools.h -- utility function declarations. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef BCFTOOLS_H #define BCFTOOLS_H #include #include #include #include #include #include #define FT_TAB_TEXT 0 // custom tab-delimited text file #define FT_GZ 1 #define FT_VCF 2 #define FT_VCF_GZ (FT_GZ|FT_VCF) #define FT_BCF (1<<2) #define FT_BCF_GZ (FT_GZ|FT_BCF) #define FT_STDIN (1<<3) char *bcftools_version(void); /// Report an error and exit -1 void error(const char *format, ...) HTS_NORETURN HTS_FORMAT(HTS_PRINTF_FMT, 1, 2); /// Report an error and exit -1. If errno != 0, appends strerror(errno). // Note: unlike error() above, the message should not end with "\n" as a // newline will be added by the function. void error_errno(const char *format, ...) HTS_NORETURN HTS_FORMAT(HTS_PRINTF_FMT, 1, 2); // For on the fly index creation with --write-index int init_index2(htsFile *fh, bcf_hdr_t *hdr, const char *fname, char **idx_fname, int idx_fmt); int init_index(htsFile *fh, bcf_hdr_t *hdr, const char *fname, char **idx_fname); // Used to set args->write_index in CLI. // It will be true if set correctly. // Note due to HTS_FMT_CSI being zero we have to use an additional bit. int write_index_parse(char *arg); void bcf_hdr_append_version(bcf_hdr_t *hdr, int argc, char **argv, const char *cmd); const char *hts_bcf_wmode(int file_type); const char *hts_bcf_wmode2(int file_type, const char *fname); void set_wmode(char dst[8], int file_type, const char *fname, int compression_level); // clevel: 0-9 with or zb type, -1 unset char *init_tmp_prefix(const char *prefix); int read_AF(bcf_sr_regions_t *tgt, bcf1_t *line, double *alt_freq); int parse_overlap_option(const char *arg); // Default sort order: chr,pos,alleles int cmp_bcf_pos(const void *aptr, const void *bptr); int cmp_bcf_pos_ref_alt(const void *aptr, const void *bptr); static inline int iupac2bitmask(char iupac) { const int A = 1; const int C = 2; const int G = 4; const int T = 8; if ( iupac >= 97 ) iupac -= 32; if ( iupac == 'A' ) return A; if ( iupac == 'C' ) return C; if ( iupac == 'G' ) return G; if ( iupac == 'T' ) return T; if ( iupac == 'M' ) return A|C; if ( iupac == 'R' ) return A|G; if ( iupac == 'W' ) return A|T; if ( iupac == 'S' ) return C|G; if ( iupac == 'Y' ) return C|T; if ( iupac == 'K' ) return G|T; if ( iupac == 'V' ) return A|C|G; if ( iupac == 'H' ) return A|C|T; if ( iupac == 'D' ) return A|G|T; if ( iupac == 'B' ) return C|G|T; if ( iupac == 'N' ) return A|C|G|T; return -1; } static inline char bitmask2iupac(int bitmask) { const char iupac[16] = {'.','A','C','M','G','R','S','V','T','W','Y','H','K','D','B','N'}; if ( bitmask <= 0 || bitmask > 15 ) return 0; return iupac[bitmask]; } static inline int iupac_consistent(char iupac, char nt) { static const char iupac_mask[90] = { 0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0, 0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0, 0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,14,2, 13,0,0,4,11,0,0,12,0,3,15,0,0,0,5,6,8,0,7,9,0,10 }; if ( iupac > 89 ) return 0; if ( nt > 90 ) nt -= 32; // lowercase if ( nt=='A' ) nt = 1; else if ( nt=='C' ) nt = 2; else if ( nt=='G' ) nt = 4; else if ( nt=='T' ) nt = 8; return iupac_mask[(int)iupac] & nt ? 1 : 0; } static inline char nt_to_upper(char nt) { if ( nt < 97 ) return nt; return nt - 32; } static inline double phred_score(double prob) { if ( prob==0 ) return 99; prob = -4.3429*log(prob); return prob>99 ? 99 : prob; } static inline double calc_binom_two_sided(int na, int nb, double aprob) { if ( !na && !nb ) return -1; if ( na==nb ) return 1; // kfunc.h implements kf_betai, which is the regularized beta function P(X<=k/N;p) = I_{1-p}(N-k,k+1) double prob = na > nb ? 2 * kf_betai(na, nb+1, aprob) : 2 * kf_betai(nb, na+1, aprob); if ( prob > 1 ) prob = 1; // this can happen, machine precision error, eg. kf_betai(1,0,0.5) return prob; } static inline double calc_binom_one_sided(int na, int nb, double aprob, int ge) { return ge ? kf_betai(na, nb + 1, aprob) : kf_betai(nb, na + 1, 1 - aprob); } static const uint64_t bcf_double_missing = 0x7ff0000000000001; static const uint64_t bcf_double_vector_end = 0x7ff0000000000002; static inline void bcf_double_set(double *ptr, uint64_t value) { union { uint64_t i; double d; } u; u.i = value; *ptr = u.d; } static inline int bcf_double_test(double d, uint64_t value) { union { uint64_t i; double d; } u; u.d = d; return u.i==value ? 1 : 0; } #define bcf_double_set_vector_end(x) bcf_double_set(&(x),bcf_double_vector_end) #define bcf_double_set_missing(x) bcf_double_set(&(x),bcf_double_missing) #define bcf_double_is_vector_end(x) bcf_double_test((x),bcf_double_vector_end) #define bcf_double_is_missing(x) bcf_double_test((x),bcf_double_missing) #define bcf_double_is_missing_or_vector_end(x) (bcf_double_test((x),bcf_double_missing) || bcf_double_test((x),bcf_double_vector_end)) static inline int get_unseen_allele(bcf1_t *line) { int i; for (i=1; in_allele; i++) { if ( !strcmp(line->d.allele[i],"<*>") ) return i; if ( !strcmp(line->d.allele[i],"") ) return i; if ( !strcmp(line->d.allele[i],"") ) return i; } return 0; } #endif bcftools-1.21/bin.c000066400000000000000000000066151467060157400142060ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include "bcftools.h" #include "bin.h" struct _bin_t { float *bins; int nbins; }; bin_t *bin_init(const char *list_def, float min, float max) { bin_t *bin = (bin_t*) calloc(1,sizeof(bin_t)); // a comma indicates a list, otherwise a file int is_file = strchr(list_def,',') ? 0 : 1; int i, nlist; char **list = hts_readlist(list_def, is_file, &nlist); if ( !list ) error("Error: failed to read %s\n",list_def); bin->nbins = nlist; bin->bins = (float*) malloc(sizeof(float)*nlist); for (i=0; ibins[i] = strtod(list[i],&tmp); if ( *tmp ) error("Could not parse %s: %s\n", list_def, list[i]); if ( min!=max && (bin->bins[i]bins[i]>max) ) error("Expected values from the interval [%f,%f], found %s\n", min, max, list[i]); free(list[i]); } free(list); if ( min!=max ) { // make sure we've got both boundaries: min,max. assert( nlist>1 ); float max_err = (bin->bins[1] - bin->bins[0])*1e-6; if ( fabs(bin->bins[0] - min) > max_err ) { bin->bins = (float*) realloc(bin->bins, (++bin->nbins)*sizeof(float)); memmove(bin->bins+1, bin->bins, sizeof(float)*(bin->nbins-1)); bin->bins[0] = min; } if ( fabs(bin->bins[bin->nbins-1] - max) > max_err ) { bin->bins = (float*) realloc(bin->bins, (++bin->nbins)*sizeof(float)); bin->bins[bin->nbins-1] = max; } } return bin; } void bin_destroy(bin_t *bin) { free(bin->bins); free(bin); } int bin_get_size(bin_t *bin) { return bin->nbins; } float bin_get_value(bin_t *bin, int idx) { return bin->bins[idx]; } int bin_get_idx(bin_t *bin, float value) { if ( bin->bins[bin->nbins-1] < value ) return bin->nbins-1; // Binary search in half-closed,half-open intervals [) int imin = 0, imax = bin->nbins - 2; while ( iminbins[i] ) imax = i - 1; else if ( value > bin->bins[i] ) imin = i + 1; else return i; } if ( bin->bins[imax] <= value ) return imax; return imin - 1; } bcftools-1.21/bin.h000066400000000000000000000042141467060157400142040ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Simple binning of float values into predefined bins */ #ifndef __BIN_H__ #define __BIN_H__ #include typedef struct _bin_t bin_t; /* * bin_init() - init bins * @list: list of half-open intervals [). If the list does not contain commas, * it is interpreted as a file name. * @min,max: extreme values. This is for user convenience so that well-known * extremes can be left out from the list. Ignored if min=max */ bin_t *bin_init(const char *list, float min, float max); void bin_destroy(bin_t *bin); /* * bin_get_size() - number of boundaries, subtract 1 to get the number of bins */ int bin_get_size(bin_t *bin); /* bin_get_idx() - find the bin index which corresponds to the value (binary search) Returns the bin index 0 <= idx <= size-2 or -1,size-1 for out of range values. */ int bin_get_idx(bin_t *bin, float value); /* bin_get_value() - get the i-th boundary value, i=0,..,size-1 */ float bin_get_value(bin_t *bin, int ith); #endif bcftools-1.21/call.h000066400000000000000000000123251467060157400143510ustar00rootroot00000000000000/* call.h -- variant calling declarations. Copyright (C) 2013-2015, 2019-2020 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __CALL_H__ #define __CALL_H__ #include #include #include "vcmp.h" #define CALL_KEEPALT 1 #define CALL_VARONLY (1<<1) #define CALL_CONSTR_TRIO (1<<2) #define CALL_CONSTR_ALLELES (1<<3) #define CALL_KEEP_UNSEEN (1<<4) #define CALL_FMT_PV4 (1<<5) #define CALL_FMT_GQ (1<<6) #define CALL_FMT_GP (1<<7) #define FATHER 0 #define MOTHER 1 #define CHILD 2 typedef struct { char *name; int sample[3]; // father, mother, child int type; // see FTYPE_* definitions in mcall.c } family_t; // For the single-sample and grouped -G calling typedef struct { double ref_lk, max_lk, lk_sum; float *qsum; // QS(quality sum) values int nqsum; uint32_t *smpl, nsmpl; uint32_t nals, als; } smpl_grp_t; // For the `-C alleles -i` constrained calling typedef struct { uint32_t n:31, used:1; char **allele; } tgt_als_t; typedef struct _ccall_t ccall_t; typedef struct { // mcall only int npdg; int *als_map, nals_map; // mapping from full set of alleles to trimmed set of alleles (old -> new) int *pl_map, npl_map; // same as above for PLs, but reverse (new -> old) char **als; // array to hold the trimmed set of alleles to appear on output int nals; // size of the als array int als_new, nals_new; // bitmask with final alleles and their number family_t *fams; // list of families and samples for trio calling int nfams, mfams; int ntrio[5][5]; // possible trio genotype combinations and their counts; first idx: uint16_t *trio[5][5]; // family type, second index: allele count (2-4, first two are unused) double *GLs; float *GPs; // FORMAT/GP: posterior probabilities int32_t *GQs, *ADs; // FORMAT/GQ: genotype qualities; AD: allelic depth for -G int32_t *itmp; // temporary int array, used for new PLs with CALL_CONSTR_ALLELES int n_itmp, nGPs, nADs; vcmp_t *vcmp; double trio_Pm_SNPs, trio_Pm_del, trio_Pm_ins; // P(mendelian) for trio calling, see mcall_call_trio_genotypes() int32_t *ugts, *cgts; // unconstraind and constrained GTs uint32_t output_tags; char *prior_AN, *prior_AC; // reference panel AF tags (AF=AC/AN) tgt_als_t *tgt_als; // for CALL_CONSTR_ALLELES char *sample_groups; // for single-sample or grouped calling with -G char *sample_groups_tag; // for -G [AD|QS:] smpl_grp_t *smpl_grp; int nsmpl_grp; // ccall only double indel_frac, min_perm_p, min_lrt; double prior_type, pref; int ngrp1_samples, n_perm; char *prior_file; ccall_t *cdat; // shared bcf_srs_t *srs; // BCF synced readers holding target alleles for CALL_CONSTR_ALLELES bcf1_t *rec; bcf_hdr_t *hdr; uint32_t flag; // One or more of the CALL_* flags defined above uint8_t *ploidy, all_diploid, unseen; double pl2p[256]; // PL to 10^(-PL/10) table int32_t *PLs; // VCF PL likelihoods (rw) int nPLs, mPLs, nac; int32_t *gts, *ac; // GTs and AC (w) double *pdg; // PLs converted to P(D|G) float *anno16; int n16; // see anno[16] in bam2bcf.h double theta; // prior } call_t; void error(const char *format, ...); /* * call() - return -1 value on critical error; -2 to skip the site; or the number of alleles on success */ int mcall(call_t *call, bcf1_t *rec); // multiallic and rare-variant calling model int ccall(call_t *call, bcf1_t *rec); // the default consensus calling model int qcall(call_t *call, bcf1_t *rec); // QCall output void mcall_init(call_t *call); void ccall_init(call_t *call); void qcall_init(call_t *call); void mcall_destroy(call_t *call); void ccall_destroy(call_t *call); void qcall_destroy(call_t *call); void call_init_pl2p(call_t *call); uint32_t *call_trio_prep(int is_x, int is_son); void init_allele_trimming_maps(call_t *call, int nals_ori, int als_out); void mcall_trim_and_update_numberR(call_t *call, bcf1_t *rec, int nals_ori, int nals_new); #endif bcftools-1.21/ccall.c000066400000000000000000000316041467060157400145100ustar00rootroot00000000000000/* ccall.c -- consensus variant calling. Copyright (C) 2013-2014 Genome Research Ltd. Portions copyright (C) 2010 Broad Institute. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include "call.h" #include "kmin.h" #include "prob1.h" // Most of the original -c calling was moved to bcftools as it was // and its data structures were wrapped into the ccal_t to make it // functional quickly. This is not the desired state. struct _ccall_t { bcf_p1aux_t *p1; }; void ccall_init(call_t *call) { call->cdat = (ccall_t*) calloc(1,sizeof(ccall_t)); call_init_pl2p(call); call->cdat->p1 = bcf_p1_init(bcf_hdr_nsamples(call->hdr), call->ploidy); call->gts = (int*) calloc(bcf_hdr_nsamples(call->hdr)*2,sizeof(int)); // assuming at most diploid everywhere call->nals_map = 5; call->als_map = (int*) malloc(sizeof(int)*call->nals_map); bcf_hdr_append(call->hdr,"##FORMAT="); if ( call->output_tags & CALL_FMT_GQ ) { bcf_hdr_append(call->hdr,"##FORMAT="); call->GQs = (int32_t*) malloc(sizeof(int32_t)*bcf_hdr_nsamples(call->hdr)); } if ( call->output_tags & CALL_FMT_GP ) error("Sorry, -f GP is not supported with -c\n"); bcf_hdr_append(call->hdr,"##INFO="); // Todo: groups not migrated to 'bcftools call' yet bcf_hdr_append(call->hdr,"##INFO="); bcf_hdr_append(call->hdr,"##INFO="); bcf_hdr_append(call->hdr,"##INFO=\n"); bcf_hdr_append(call->hdr,"##INFO=\n"); bcf_hdr_append(call->hdr,"##INFO=\n"); bcf_hdr_append(call->hdr,"##INFO=\n"); bcf_hdr_append(call->hdr,"##INFO=\n"); // bcf_hdr_append(call->hdr,); // bcf_hdr_append(call->hdr,); bcf_hdr_append(call->hdr,"##INFO="); return; } void ccall_destroy(call_t *call) { free(call->itmp); free(call->als_map); free(call->gts); free(call->anno16); free(call->PLs); free(call->GQs); free(call->pdg); bcf_p1_destroy(call->cdat->p1); free(call->cdat); return; } // Inits P(D|G): convert PLs from log space, only two alleles (three PLs) are used. // NB: The original samtools calling code uses pdgs in reverse order (AA comes // first, RR last), while the -m calling model uses the canonical order. static void set_pdg3(double *pl2p, int *PLs, double *pdg, int n_smpl, int n_gt) { int i; for (i=0; ip[0] = a->p[1] = a->p[2] = a->p[3] = 1.; for (i=0; i<4; i++) a->d[i] = anno[i]; a->depth = anno[0] + anno[1] + anno[2] + anno[3]; a->is_tested = (anno[0] + anno[1] > 0 && anno[2] + anno[3] > 0); if (a->depth == 0) return -1; a->mq = (int)(sqrt((anno[9] + anno[11]) / a->depth) + .499); kt_fisher_exact(anno[0], anno[1], anno[2], anno[3], &left, &right, &a->p[0]); for (i = 1; i < 4; ++i) a->p[i] = ttest(anno[0] + anno[1], anno[2] + anno[3], anno+4*i); return 0; } int test16(float *anno16, anno16_t *a) { a->p[0] = a->p[1] = a->p[2] = a->p[3] = 1.; a->d[0] = a->d[1] = a->d[2] = a->d[3] = 0.; a->mq = a->depth = a->is_tested = 0; return test16_core(anno16, a); } static int update_bcf1(call_t *call, bcf1_t *rec, const bcf_p1rst_t *pr, double em[10]) { int has_I16, is_var; float fq, r; anno16_t a; float tmpf[4], tmpi; bcf_get_info_float(call->hdr, rec, "I16", &call->anno16, &call->n16); has_I16 = test16(call->anno16, &a) >= 0? 1 : 0; // print EM if (em[0] >= 0) { tmpf[0] = 1 - em[0]; bcf_update_info_float(call->hdr, rec, "AF1", tmpf, 1); } if (em[4] >= 0 && em[4] <= 0.05) { tmpf[0] = em[3]; tmpf[1] = em[2]; tmpf[2] = em[1]; tmpf[3] = em[4]; bcf_update_info_float(call->hdr, rec, "G3", tmpf, 3); bcf_update_info_float(call->hdr, rec, "HWE", &tmpf[3], 1); } if (em[5] >= 0 && em[6] >= 0) { tmpf[0] = 1 - em[5]; tmpf[1] = 1 - em[6]; bcf_update_info_float(call->hdr, rec, "AF2", tmpf, 2); } if (em[7] >= 0) { tmpf[0] = em[7]; bcf_update_info_float(call->hdr, rec, "LRT", tmpf, 1); } if (em[8] >= 0) { tmpf[0] = em[8]; bcf_update_info_float(call->hdr, rec, "LRT2", tmpf, 1); } bcf_p1aux_t *p1 = call->cdat->p1; if (p1->cons_llr > 0) { tmpi = p1->cons_llr; bcf_update_info_int32(call->hdr, rec, "CLR", &tmpi, 1); // todo: trio calling with -c if (p1->cons_gt > 0) { char tmp[4]; tmp[0] = p1->cons_gt&0xff; tmp[1] = p1->cons_gt>>8&0xff; tmp[2] = p1->cons_gt>>16&0xff; tmp[3] = 0; bcf_update_info_string(call->hdr, rec, "UGT", tmp); tmp[0] = p1->cons_gt>>32&0xff; tmp[1] = p1->cons_gt>>40&0xff; tmp[2] = p1->cons_gt>>48&0xff; bcf_update_info_string(call->hdr, rec, "CGT", tmp); } } is_var = (pr->p_ref < call->pref); r = is_var? pr->p_ref : pr->p_var; bcf_update_info_int32(call->hdr, rec, "AC1", &pr->ac, 1); int32_t dp[4]; dp[0] = call->anno16[0]; dp[1] = call->anno16[1]; dp[2] = call->anno16[2]; dp[3] = call->anno16[3]; bcf_update_info_int32(call->hdr, rec, "DP4", dp, 4); bcf_update_info_int32(call->hdr, rec, "MQ", &a.mq, 1); fq = pr->p_ref_folded < 0.5? -4.343 * log(pr->p_ref_folded) : 4.343 * log(pr->p_var_folded); if (fq < -999) fq = -999; if (fq > 999) fq = 999; bcf_update_info_float(call->hdr, rec, "FQ", &fq, 1); assert( pr->cmp[0]<0 ); // todo // if (pr->cmp[0] >= 0.) { // two sample groups // int i, q[3]; // for (i = 1; i < 3; ++i) { // double x = pr->cmp[i] + pr->cmp[0]/2.; // q[i] = x == 0? 255 : (int)(-4.343 * log(x) + .499); // if (q[i] > 255) q[i] = 255; // } // if (pr->perm_rank >= 0) ksprintf(&s, "PR=%d;", pr->perm_rank); // // ksprintf(&s, "PCHI2=%.3g;PC2=%d,%d;", q[1], q[2], pr->p_chi2); // } if (has_I16 && a.is_tested) { int i; for (i=0; i<4; i++) tmpf[i] = a.p[i]; bcf_update_info_float(call->hdr, rec, "PV4", tmpf, 4); } bcf_update_info_int32(call->hdr, rec, "I16", NULL, 0); // remove I16 tag bcf_update_info_int32(call->hdr, rec, "QS", NULL, 0); // remove QS tag rec->qual = r < 1e-100? 999 : -4.343 * log(r); if (rec->qual > 999) rec->qual = 999; // Remove unused alleles int nals_ori = rec->n_allele, nals = !is_var && !(call->flag & CALL_KEEPALT) ? 1 : pr->rank0 < 2? 2 : pr->rank0+1; if ( call->flag & CALL_KEEPALT && call->unseen==nals-1 ) nals--; if ( nalsn_allele ) { bcf_update_alleles(call->hdr, rec, (const char**)rec->d.allele, nals); // Update PLs int npls_src = call->nPLs / rec->n_sample, npls_dst = nals*(nals+1)/2; int *pls_src = call->PLs - npls_src, *pls_dst = call->PLs - npls_dst; int isample, i; for (isample = 0; isample < rec->n_sample; isample++) { pls_src += npls_src; pls_dst += npls_dst; if ( !call->ploidy || call->ploidy[isample]==2 ) { for (i=0; ihdr, rec, "PL", call->PLs, npls_dst*rec->n_sample); } // Call genotypes int i; for (i=0; in_sample; i++) { int x = ( is_var || call->output_tags & CALL_FMT_GQ ) ? bcf_p1_call_gt(p1, pr->f_exp, i, is_var) : 2; int gt = x&3; if ( !call->ploidy || call->ploidy[i]==2 ) { if ( gt==1 ) { call->gts[2*i] = bcf_gt_unphased(0); call->gts[2*i+1] = bcf_gt_unphased(1); } else if ( gt==0 ) { call->gts[2*i] = bcf_gt_unphased(1); call->gts[2*i+1] = bcf_gt_unphased(1); } else { call->gts[2*i] = bcf_gt_unphased(0); call->gts[2*i+1] = bcf_gt_unphased(0); } if ( call->output_tags & CALL_FMT_GQ ) call->GQs[i] = x>>2; } else { if ( gt==0 ) call->gts[2*i] = bcf_gt_unphased(1); else call->gts[2*i] = bcf_gt_unphased(0); call->gts[2*i+1] = bcf_int32_vector_end; if ( call->output_tags & CALL_FMT_GQ ) call->GQs[i] = bcf_int32_missing; } } bcf_update_genotypes(call->hdr, rec, call->gts, rec->n_sample*2); if ( call->output_tags & CALL_FMT_GQ ) bcf_update_format_int32(call->hdr, rec, "GQ", call->GQs, rec->n_sample); // trim Number=R tags int out_als = 0; for (i=0; ihdr); // Get the genotype likelihoods int nals = rec->n_allele; call->nPLs = bcf_get_format_int32(call->hdr, rec, "PL", &call->PLs, &call->mPLs); if ( call->nPLs!=nsmpl*nals*(nals+1)/2 && call->nPLs!=nsmpl*nals ) // diploid+haploid or haploid only error("Wrong number of PL fields? nals=%d npl=%d\n", nals,call->nPLs); // Convert PLs to probabilities, only first two alleles are considered int ngts = nals*(nals+1)/2; hts_expand(double, 3*nsmpl, call->npdg, call->pdg); set_pdg3(call->pl2p, call->PLs, call->pdg, nsmpl, ngts); double em[10] = {-1.,-1.,-1.,-1.,-1.,-1.,-1.,-1.,-1.,-1.}; int ret = bcf_em1(call, rec, call->ngrp1_samples, 0x1ff, em); bcf_p1rst_t pr; int do_contrast = (em[7] >= 0 && em[7] < call->min_lrt) ? 1 : 0; ret = bcf_p1_cal(call, rec, do_contrast, call->cdat->p1, &pr); if (pr.p_ref >= call->pref && (call->flag & CALL_VARONLY)) return 0; if (ret >= 0) ret = update_bcf1(call, rec, &pr, em); return ret; } bcftools-1.21/cigar_state.h000066400000000000000000000151201467060157400157170ustar00rootroot00000000000000/* cigar_state.h -- API for efficient parsing of CIGAR strings Copyright (C) 2022 Genome Research Ltd. Author: pd3@sanger Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef CIGAR_STATE_H #define CIGAR_STATE_H #include #include #include typedef struct { bam1_t *bam; uint32_t *cigar; uint8_t *seq; int ncig; int icig; // position in the cigar string int iseq; // the cigar[icigar] operation refers to &seq[iseq] hts_pos_t ref_pos; // reference coordinate, corresponds to iseq; points to // the first base after the read when consumed } cigar_state_t; static inline void cstate_init(cigar_state_t *cs, bam1_t *bam) { cs->bam = bam; cs->cigar = bam_get_cigar(bam); cs->seq = bam_get_seq(bam); cs->ncig = bam->core.n_cigar; cs->icig = 0; cs->iseq = 0; cs->ref_pos = bam->core.pos; } /** * cstate_seek_fwd() - Move in the cigar forward to find query index that * matches the reference position. * * When the position is not contained within the sequence, either because there * is a deletion or there is no overlap, the behavior is controlled by the value * of trim_left: * - read starts after: qry_beg > pos && trim_left=1 .. returns 0 and sets pos to qry_beg * - read starts after: qry_beg > pos && trim_left=0 .. returns -1 * - read ends before: qry_end < pos && trim_left=1 .. returns -2 * - read ends before: qry_end < pos && trim_left=0 .. returns qry_len-1 and sets pos to qry_end * - pos inside a deletion && trim_left=1 .. returns position after the deletion * - pos inside a deletion && trim_left=0 .. returns position before the deletion */ static inline int cstate_seek_fwd(cigar_state_t *cs, hts_pos_t *pos_ptr, int trim_left) { hts_pos_t pos = *pos_ptr; while ( cs->ref_pos <= pos ) { if ( cs->icig >= cs->ncig ) // the read ends before pos { if ( trim_left ) return -2; *pos_ptr = cs->ref_pos - 1; return cs->iseq - 1; } int op = cs->cigar[cs->icig] & BAM_CIGAR_MASK; int len = cs->cigar[cs->icig] >> BAM_CIGAR_SHIFT; if ( op==BAM_CMATCH || op==BAM_CEQUAL || op==BAM_CDIFF ) { if ( cs->ref_pos + len > pos ) return pos - cs->ref_pos + cs->iseq; // the cigar op overlaps pos cs->ref_pos += len; cs->iseq += len; cs->icig++; continue; } if ( op==BAM_CINS || op==BAM_CSOFT_CLIP ) { cs->iseq += len; cs->icig++; continue; } if ( op==BAM_CDEL || op==BAM_CREF_SKIP ) { if ( cs->ref_pos + len > pos ) { // The deletion overlaps the position. NB: assuming del is never the first or last op *pos_ptr = trim_left ? cs->ref_pos + len : cs->ref_pos - 1; return trim_left ? cs->iseq : cs->iseq - 1; } cs->ref_pos += len; cs->icig++; continue; } if ( op==BAM_CHARD_CLIP || op==BAM_CPAD ) { cs->icig++; continue; } error("FIXME: not ready for CIGAR operator %d\n",op); } // the read starts after pos if ( trim_left ) { *pos_ptr = cs->bam->core.pos; return 0; } return -1; } /** * cstate_seek_op_fwd() - Move in the cigar forward to find query index that * matches the seek operator and the reference position. * * In order to match a deletion, pass the position of the first deleted base. * In order to match an insertion, pass the reference coordinate of the base * after the inserted sequence. * * Returns the index to the query sequence cs->seq * on success; -1 when there is no such matching position but the cigar * is still not entirely consumed (e.g. a deletion or a soft-clip); -2 * when there is no overlap (i.e. the read ends before the position). */ static inline int cstate_seek_op_fwd(cigar_state_t *cs, hts_pos_t pos, int seek_op, int *oplen) { while ( cs->ref_pos <= pos ) { if ( cs->icig >= cs->ncig ) return -2; int op = cs->cigar[cs->icig] & BAM_CIGAR_MASK; int len = cs->cigar[cs->icig] >> BAM_CIGAR_SHIFT; if ( op==BAM_CMATCH || op==BAM_CEQUAL || op==BAM_CDIFF ) { if ( cs->ref_pos + len <= pos ) { cs->ref_pos += len; cs->iseq += len; cs->icig++; continue; } if ( seek_op==BAM_CMATCH ) return pos - cs->ref_pos + cs->iseq; return -1; } if ( op==BAM_CINS || op==BAM_CSOFT_CLIP ) { if ( cs->ref_pos == pos && seek_op==op ) { if ( oplen ) *oplen = len; return cs->iseq; } if ( cs->ref_pos >= pos ) return -1; cs->iseq += len; cs->icig++; continue; } if ( op==BAM_CDEL || op==BAM_CREF_SKIP ) { if ( cs->ref_pos == pos && seek_op==op ) { if ( oplen ) *oplen = len; return cs->iseq; } if ( cs->ref_pos >= pos ) return -1; cs->ref_pos += len; cs->icig++; continue; } if ( op==BAM_CHARD_CLIP || op==BAM_CPAD ) { cs->icig++; continue; } error("FIXME: not ready for CIGAR operator %d\n",op); } return cs->icig < cs->ncig ? -1 : -2; } #endif bcftools-1.21/cols.c000066400000000000000000000064131467060157400143720ustar00rootroot00000000000000/* Copyright (C) 2019 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include "cols.h" cols_t *cols_split(const char *line, cols_t *cols, char delim) { if ( !cols ) cols = (cols_t*) calloc(1,sizeof(cols_t)); if ( cols->rmme ) free(cols->rmme); cols->n = 0; cols->rmme = strdup(line); char *ss = cols->rmme; while (1) { char *se = ss; while ( *se && *se!=delim ) se++; char tmp = *se; *se = 0; cols->n++; if ( cols->n > cols->m ) { cols->m += 10; cols->off = (char**) realloc(cols->off, sizeof(*cols->off)*cols->m); } cols->off[ cols->n - 1 ] = ss; if ( !tmp ) break; ss = se + 1; } return cols; } void cols_append(cols_t *cols, char *str) { if ( cols->rmme ) { size_t str_len = strlen(str); size_t lst_len = strlen(cols->off[ cols->n - 1 ]); size_t tot_len = 2 + str_len + lst_len + (cols->off[ cols->n - 1 ] - cols->rmme); cols_t *tmp_cols = (cols_t*)calloc(1,sizeof(cols_t)); tmp_cols->rmme = (char*) calloc(tot_len,1); tmp_cols->off = (char**) calloc(cols->n+1,sizeof(*tmp_cols->off)); char *ptr = tmp_cols->rmme; int i; for (i=0; in; i++) { size_t len = strlen(cols->off[i]); memcpy(ptr, cols->off[i], len); tmp_cols->off[i] = ptr; ptr += len + 1; } memcpy(ptr, str, str_len); tmp_cols->off[i] = ptr; free(cols->off); free(cols->rmme); cols->rmme = tmp_cols->rmme; cols->off = tmp_cols->off; cols->n = cols->n+1; cols->m = cols->n; free(tmp_cols); return; } cols->n++; if ( cols->n > cols->m ) { cols->m++; cols->off = (char**) realloc(cols->off,sizeof(*cols->off)*cols->m); } cols->off[cols->n-1] = str; } void cols_clear(cols_t *cols) { if ( !cols ) return; free(cols->rmme); free(cols->off); cols->rmme = NULL; cols->off = NULL; } void cols_destroy(cols_t *cols) { if ( !cols ) return; cols_clear(cols); free(cols); } bcftools-1.21/cols.h000066400000000000000000000034201467060157400143720ustar00rootroot00000000000000/* Copyright (C) 2019 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __COLS_H__ #define __COLS_H__ #include typedef struct { int n,m; char **off, *rmme; } cols_t; /* cols_split() can be called repeatedly to split new strings, memory is allocated and deallocated automatically */ cols_t *cols_split(const char *line, cols_t *cols, char delim); /* Although cols_append() can be combined with cols_split(), it is much slower and the string must exist throughout the life of cols unless initialized with cols_split(). */ void cols_append(cols_t *cols, char *str); void cols_clear(cols_t *cols); void cols_destroy(cols_t *cols); #endif bcftools-1.21/config.mk.in000066400000000000000000000051131467060157400154650ustar00rootroot00000000000000# Optional configure Makefile overrides for bcftools. # # Copyright (C) 2015,2017, 2019 Genome Research Ltd. # # Author: John Marshall # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. # This is @configure_input@ # # If you use configure, this file overrides variables and augments rules # in the Makefile to reflect your configuration choices. If you don't run # configure, the main Makefile contains suitable conservative defaults. prefix = @prefix@ exec_prefix = @exec_prefix@ bindir = @bindir@ libexecdir = @libexecdir@ datarootdir = @datarootdir@ mandir = @mandir@ CC = @CC@ CPPFLAGS = @CPPFLAGS@ CFLAGS = @CFLAGS@ LDFLAGS = @LDFLAGS@ LIBS = @LIBS@ DYNAMIC_FLAGS = @CC_RDYNAMIC_OPT@ USE_GPL = @USE_GPL@ GSL_LIBS = @GSL_LIBS@ PERL_CFLAGS = @PERL_CCOPTS@ PERL_LIBS = @PERL_LIBS@ PLATFORM = @PLATFORM@ PLUGINS_ENABLED = @enable_bcftools_plugins@ plugindir = @bcf_plugindir@ pluginpath = @bcf_pluginpath@ PLUGIN_EXT = @PLUGIN_EXT@ @Hsource@HTSDIR = @HTSDIR@ @Hsource@include $(HTSDIR)/htslib.mk @Hsource@include $(HTSDIR)/htslib_static.mk @Hsource@HTSLIB = $(HTSDIR)/libhts.a @Hsource@HTSLIB_LIB = $(HTSLIB) $(HTSLIB_static_LIBS) @Hsource@HTSLIB_DLL = $(HTSDIR)/@HTSLIB_DLL@ @Hsource@HTSLIB_LDFLAGS = $(HTSLIB_static_LDFLAGS) @Hsource@W32_PLUGIN_LIBS = libbcftools.a $(HTSLIB_DLL) $(ALL_LIBS) @Hsource@BGZIP = $(HTSDIR)/bgzip @Hsource@TABIX = $(HTSDIR)/tabix HTSLIB_CPPFLAGS = @HTSLIB_CPPFLAGS@ @Hinstall@HTSLIB_LDFLAGS = @HTSLIB_LDFLAGS@ @Hinstall@HTSLIB_LIB = -lhts @Hinstall@W32_PLUGIN_LIBS = libbcftools.a $(HTSLIB_LDFLAGS) $(HTSLIB_LIB) $(ALL_LIBS) bcftools-1.21/configure.ac000066400000000000000000000265161467060157400155620ustar00rootroot00000000000000# Configure script for bcftools, utilities for VCF/BCF files. # # Copyright (C) 2015,2017-2020 Genome Research Ltd. # # Author: John Marshall # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. dnl Process this file with autoconf to produce a configure script AC_INIT([BCFtools], m4_esyscmd_s([./version.sh 2>/dev/null]), [samtools-help@lists.sourceforge.net], [], [http://www.htslib.org/]) AC_PREREQ([2.63]) dnl This version introduced 4-argument AC_CHECK_HEADER AC_CONFIG_SRCDIR([main.c]) AC_CONFIG_HEADERS([config.h]) m4_include([m4/ax_with_htslib.m4]) m4_include([m4/hts_prog_cc_warnings.m4]) dnl Copyright notice to be copied into the generated configure script AC_COPYRIGHT([Portions copyright (C) 2015,2017-2020 Genome Research Ltd. This configure script is free software: you are free to change and redistribute it. There is NO WARRANTY, to the extent permitted by law.]) AC_PROG_CC dnl Turn on compiler warnings, if possible HTS_PROG_CC_WARNINGS dnl Flags to treat warnings as errors. 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AC_SEARCH_LIBS(regcomp, regex, [libregex=needed], []) dnl Force POSIX mode on Windows/Mingw test -n "$host_alias" || host_alias=unknown-`uname -s` case $host_alias in *-msys* | *-MSYS* | *-mingw* | *-MINGW*) host_result="MSYS dll" PLATFORM=MSYS PLUGIN_EXT=.dll # This also sets __USE_MINGW_ANSI_STDIO which in turn makes PRId64, # %lld and %z printf formats work. It also enforces the snprintf to # be C99 compliant so it returns the correct values (in kstring.c). CPPFLAGS="$CPPFLAGS -D_XOPEN_SOURCE=600" ;; esac AC_CONFIG_FILES([config.mk]) AC_OUTPUT AS_IF([test "x$USE_GPL" != "x"], [dnl AC_MSG_NOTICE([License has been changed to GPL. Linking against the GNU scientific library requires that the resulting binary is licensed using the GNU General Public License. In particular, this means you will have to follow the terms of this license in order to distribute binary copies. For more information see the INSTALL file. Text of the GNU General Public License can be found in the LICENSE file, or at http://www.gnu.org/copyleft/gpl.html Information on the GNU Scientific Library, including the rationale for its choice of license can be found at https://www.gnu.org/software/gsl/ ])]) bcftools-1.21/consensus.c000066400000000000000000001510621467060157400154530ustar00rootroot00000000000000/* The MIT License Copyright (c) 2014-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "regidx.h" #include "bcftools.h" #include "rbuf.h" #include "filter.h" #include "smpl_ilist.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define PICK_REF 1 #define PICK_ALT 2 #define PICK_LONG 4 #define PICK_SHORT 8 #define PICK_IUPAC 16 #define TO_UPPER 1 #define TO_LOWER 2 typedef struct { int num; // number of ungapped blocks in this chain int *block_lengths; // length of the ungapped blocks in this chain int *ref_gaps; // length of the gaps on the reference sequence between blocks int *alt_gaps; // length of the gaps on the alternative sequence between blocks int ori_pos; int ref_last_block_ori; // start position on the reference sequence of the following ungapped block (0-based) int alt_last_block_ori; // start position on the alternative sequence of the following ungapped block (0-based) } chain_t; #define MASK_LC 1 #define MASK_UC 2 #define MASK_SKIP(x) (((x)->with!=MASK_LC && (x)->with!=MASK_UC) ? 1 : 0) typedef struct { char *fname, with; regidx_t *idx; regitr_t *itr; } mask_t; typedef struct { kstring_t fa_buf; // buffered reference sequence int fa_ori_pos; // start position of the fa_buffer (wrt original sequence) int fa_frz_pos; // protected position to avoid conflicting variants (last pos for SNPs/ins) int fa_mod_off; // position difference of fa_frz_pos in the ori and modified sequence (ins positive) int fa_frz_mod; // the fa_buf offset of the protected fa_frz_pos position, includes the modified sequence int fa_end_pos; // region's end position in the original sequence int fa_length; // region's length in the original sequence (in case end_pos not provided in the FASTA header) int fa_case; // output upper case or lower case: TO_UPPER|TO_LOWER int fa_src_pos; // last genomic coordinate read from the input fasta (0-based) char prev_base; // this is only to validate the REF allele in the VCF - the modified fa_buf cannot be used for inserts following deletions, see 600#issuecomment-383186778 int prev_base_pos; // the position of prev_base int prev_is_insert; rbuf_t vcf_rbuf; bcf1_t **vcf_buf; int nvcf_buf, rid; char *chr, *chr_prefix; mask_t *mask; int nmask; int chain_id; // chain_id, to provide a unique ID to each chain in the chain output chain_t *chain; // chain structure to store the sequence of ungapped blocks between the ref and alt sequences // Note that the chain is re-initialised for each chromosome/seq_region filter_t *filter; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE bcf_srs_t *files; bcf_hdr_t *hdr; FILE *fp_out; FILE *fp_chain; char **argv; int argc, output_iupac, iupac_GTs, haplotype, allele, isample, napplied; uint8_t *iupac_bitmask, *iupac_als; int miupac_bitmask, miupac_als, regions_overlap; char *fname, *ref_fname, *sample, *sample_fname, *output_fname, *mask_fname, *chain_fname, missing_allele, absent_allele; char mark_del, mark_ins, mark_snv; smpl_ilist_t *smpl; } args_t; static void destroy_chain(chain_t *chain) { if ( !chain ) return; free(chain->ref_gaps); free(chain->alt_gaps); free(chain->block_lengths); free(chain); } static chain_t* init_chain(chain_t *chain, int ref_ori_pos) { if ( chain ) destroy_chain(chain); chain = (chain_t*) calloc(1,sizeof(chain_t)); chain->num = 0; chain->block_lengths = NULL; chain->ref_gaps = NULL; chain->alt_gaps = NULL; chain->ori_pos = ref_ori_pos; chain->ref_last_block_ori = ref_ori_pos; chain->alt_last_block_ori = ref_ori_pos; return chain; } static void print_chain(args_t *args) { /* Example chain format (see: https://genome.ucsc.edu/goldenPath/help/chain.html): chain 1 500 + 480 500 1 501 + 480 501 1 12 3 1 1 0 3 484 chain line is: - chain - score (sum of the length of ungapped block in this case) - ref_seqname (from the fasta header, parsed by htslib) - ref_seqlength (from the fasta header) - ref_strand (+ or -; always + for bcf-consensus) - ref_start (as defined in the fasta header) - ref_end (as defined in the fasta header) - alt_seqname (same as ref_seqname as bcf-consensus only considers SNPs and indels) - alt_seqlength (adjusted to match the length of the alt sequence) - alt_strand (+ or -; always + for bcf-consensus) - alt_start (same as ref_start, as no edits are recorded/applied before that position) - alt_end (adjusted to match the length of the alt sequence) - chain_num (just an auto-increment id) the other (sorted) lines are: - length of the ungapped alignment block - gap on the ref sequence between this and the next block (all but the last line) - gap on the alt sequence between this and the next block (all but the last line) */ chain_t *chain = args->chain; int n = chain->num; int ref_end_pos = args->fa_length + chain->ori_pos; int last_block_size = ref_end_pos - chain->ref_last_block_ori; int alt_end_pos = chain->alt_last_block_ori + last_block_size; int score = 0; for (n=0; nnum; n++) { score += chain->block_lengths[n]; } score += last_block_size; fprintf(args->fp_chain, "chain %d %s %d + %d %d %s %d + %d %d %d\n", score, args->chr, ref_end_pos, chain->ori_pos, ref_end_pos, args->chr, alt_end_pos, chain->ori_pos, alt_end_pos, ++args->chain_id); for (n=0; nnum; n++) { fprintf(args->fp_chain, "%d %d %d\n", chain->block_lengths[n], chain->ref_gaps[n], chain->alt_gaps[n]); } fprintf(args->fp_chain, "%d\n\n", last_block_size); } static void push_chain_gap(chain_t *chain, int ref_start, int ref_len, int alt_start, int alt_len) { // fprintf(stderr, "push_chain_gap(chain=%p, ref_start=%d, ref_len=%d, alt_start=%d, alt_len=%d)\n", chain, ref_start, ref_len, alt_start, alt_len); int num = chain->num; if (num && ref_start <= chain->ref_last_block_ori) { // In case this variant is back-to-back with the previous one chain->ref_last_block_ori = ref_start + ref_len; chain->alt_last_block_ori = alt_start + alt_len; chain->ref_gaps[num-1] += ref_len; chain->alt_gaps[num-1] += alt_len; } else { // Extend the ungapped blocks, store the gap length chain->block_lengths = (int*) realloc(chain->block_lengths, (num + 1) * sizeof(int)); chain->ref_gaps = (int*) realloc(chain->ref_gaps, (num + 1) * sizeof(int)); chain->alt_gaps = (int*) realloc(chain->alt_gaps, (num + 1) * sizeof(int)); chain->block_lengths[num] = ref_start - chain->ref_last_block_ori; chain->ref_gaps[num] = ref_len; chain->alt_gaps[num] = alt_len; // Update the start positions of the next block chain->ref_last_block_ori = ref_start + ref_len; chain->alt_last_block_ori = alt_start + alt_len; // Increment the number of ungapped blocks chain->num++; } } static void init_data(args_t *args) { args->files = bcf_sr_init(); args->files->require_index = 1; if ( !bcf_sr_add_reader(args->files,args->fname) ) error("Failed to read from %s: %s\n", !strcmp("-",args->fname)?"standard input":args->fname, bcf_sr_strerror(args->files->errnum)); args->hdr = args->files->readers[0].header; args->isample = -1; if ( !args->sample ) { args->smpl = smpl_ilist_init(args->hdr,NULL,0,SMPL_NONE|SMPL_VERBOSE); if ( !args->smpl->n ) { smpl_ilist_destroy(args->smpl); args->smpl = NULL; } } else if ( args->sample && strcmp("-",args->sample) ) { args->smpl = smpl_ilist_init(args->hdr,args->sample,0,SMPL_NONE|SMPL_VERBOSE); if ( args->smpl && !args->smpl->n ) error("No matching sample found\n"); } else if ( args->sample_fname ) { args->smpl = smpl_ilist_init(args->hdr,args->sample_fname,1,SMPL_NONE|SMPL_VERBOSE); if ( args->smpl && !args->smpl->n ) error("No matching sample found\n"); } if ( args->smpl ) { if ( args->haplotype || args->allele ) { if ( args->smpl->n > 1 ) error("Too many samples, only one can be used with -H; check the -s,-S options\n"); args->isample = args->smpl->idx[0]; } else { args->iupac_GTs = 1; if ( args->smpl->n==1 ) fprintf(stderr,"Note: applying IUPAC codes based on FORMAT/GT in sample %s\n",bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->smpl->idx[0])); else fprintf(stderr,"Note: applying IUPAC codes based on FORMAT/GT in %d samples\n",args->smpl->n); } } else if ( args->output_iupac ) fprintf(stderr,"Note: applying IUPAC codes based on REF,ALT%s\n",bcf_hdr_nsamples(args->hdr)?", ignoring samples":""); else fprintf(stderr,"Note: applying REF,ALT variants%s\n",bcf_hdr_nsamples(args->hdr)?", ignoring samples":""); int i; for (i=0; inmask; i++) { mask_t *mask = &args->mask[i]; mask->idx = regidx_init(mask->fname,NULL,NULL,0,NULL); if ( !mask->idx ) error("Failed to initialize mask regions\n"); mask->itr = regitr_init(mask->idx); } // In case we want to store the chains if ( args->chain_fname ) { args->fp_chain = fopen(args->chain_fname,"w"); if ( ! args->fp_chain ) error("Failed to create %s: %s\n", args->chain_fname, strerror(errno)); args->chain_id = 0; } rbuf_init(&args->vcf_rbuf, 100); args->vcf_buf = (bcf1_t**) calloc(args->vcf_rbuf.m, sizeof(bcf1_t*)); if ( args->output_fname ) { args->fp_out = fopen(args->output_fname,"w"); if ( ! args->fp_out ) error("Failed to create %s: %s\n", args->output_fname, strerror(errno)); } else args->fp_out = stdout; if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); args->rid = -1; } static void add_mask(args_t *args, char *fname) { args->nmask++; args->mask = (mask_t*)realloc(args->mask,args->nmask*sizeof(*args->mask)); mask_t *mask = &args->mask[args->nmask-1]; mask->fname = fname; mask->with = 'N'; } static void add_mask_with(args_t *args, char *with) { if ( !args->nmask ) error("The --mask-with option must follow --mask\n"); mask_t *mask = &args->mask[args->nmask-1]; if ( !strcasecmp(with,"uc") ) mask->with = MASK_UC; else if ( !strcasecmp(with,"lc") ) mask->with = MASK_LC; else if ( strlen(with)!=1 ) error("Expected \"lc\", \"uc\", or a single character with the --mask-with option\n"); else mask->with = *with; } static void destroy_data(args_t *args) { free(args->iupac_als); free(args->iupac_bitmask); if (args->filter) filter_destroy(args->filter); if ( args->smpl ) smpl_ilist_destroy(args->smpl); bcf_sr_destroy(args->files); int i; for (i=0; ivcf_rbuf.m; i++) if ( args->vcf_buf[i] ) bcf_destroy1(args->vcf_buf[i]); free(args->vcf_buf); free(args->fa_buf.s); free(args->chr); for (i=0; inmask; i++) { mask_t *mask = &args->mask[i]; regidx_destroy(mask->idx); regitr_destroy(mask->itr); } free(args->mask); if ( args->chain_fname ) if ( fclose(args->fp_chain) ) error("Close failed: %s\n", args->chain_fname); if ( fclose(args->fp_out) ) error("Close failed: %s\n", args->output_fname); destroy_chain(args->chain); } static void init_region(args_t *args, char *line) { char *ss, *se = line; while ( *se && !isspace(*se) && *se!=':' ) se++; hts_pos_t from = 0, to = 0; char tmp = 0, *tmp_ptr = NULL; if ( *se ) { tmp = *se; *se = 0; tmp_ptr = se; ss = ++se; from = strtol(ss,&se,10); if ( ss==se || !*se || *se!='-' ) from = 0; else { from--; ss = ++se; to = strtol(ss,&se,10); if ( ss==se || (*se && !isspace(*se)) ) { from = 0; to = 0; } else to--; } } free(args->chr); args->chr = strdup(line); args->rid = bcf_hdr_name2id(args->hdr,line); if ( args->rid<0 ) fprintf(stderr,"Warning: Sequence \"%s\" not in %s\n", line,args->fname); args->prev_base_pos = -1; args->fa_buf.l = 0; args->fa_length = 0; args->fa_end_pos = to; // 0-based args->fa_ori_pos = from; // 0-based args->fa_src_pos = from; // 0-based args->fa_mod_off = 0; args->fa_frz_pos = -1; args->fa_frz_mod = -1; args->fa_case = -1; args->vcf_rbuf.n = 0; // bcf_sr_set_regions accepts 1-based coordinates kstring_t str = {0,0,0}; if ( !from ) from = 1; else from++; #ifndef MAX_CSI_COOR #define MAX_CSI_COOR ((1LL << (14 + 30)) - 1) #endif if ( to==0 ) to = MAX_CSI_COOR - 1; else to++; ksprintf(&str,"%s:%"PRIhts_pos"-%"PRIhts_pos,line,from,to); bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); bcf_sr_set_regions(args->files,str.s,0); free(str.s); if ( tmp_ptr ) *tmp_ptr = tmp; fprintf(args->fp_out,">%s%s\n",args->chr_prefix?args->chr_prefix:"",line); if ( args->chain_fname ) args->chain = init_chain(args->chain, args->fa_ori_pos); } static bcf1_t **next_vcf_line(args_t *args) { if ( args->vcf_rbuf.n ) { int i = rbuf_shift(&args->vcf_rbuf); return &args->vcf_buf[i]; } while ( bcf_sr_next_line(args->files) ) { if ( args->filter ) { int is_ok = filter_test(args->filter, bcf_sr_get_line(args->files,0), NULL); if ( args->filter_logic & FLT_EXCLUDE ) is_ok = is_ok ? 0 : 1; if ( !is_ok ) continue; } return &args->files->readers[0].buffer[0]; } return NULL; } static void unread_vcf_line(args_t *args, bcf1_t **rec_ptr) { bcf1_t *rec = *rec_ptr; if ( args->vcf_rbuf.n >= args->vcf_rbuf.m ) error("FIXME: too many overlapping records near %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); // Insert the new record in the buffer. The line would be overwritten in // the next bcf_sr_next_line call, therefore we need to swap it with an // unused one int i = rbuf_append(&args->vcf_rbuf); if ( !args->vcf_buf[i] ) args->vcf_buf[i] = bcf_init1(); bcf1_t *tmp = rec; *rec_ptr = args->vcf_buf[i]; args->vcf_buf[i] = tmp; } static void flush_fa_buffer(args_t *args, int len) { if ( !args->fa_buf.l ) return; int nwr = 0; while ( nwr + 60 <= args->fa_buf.l ) { if ( fwrite(args->fa_buf.s+nwr,1,60,args->fp_out) != 60 ) error("Could not write: %s\n", args->output_fname); if ( fwrite("\n",1,1,args->fp_out) != 1 ) error("Could not write: %s\n", args->output_fname); nwr += 60; } if ( nwr ) args->fa_ori_pos += nwr; args->fa_frz_mod -= nwr; if ( len ) { // not finished on this chr yet and the buffer cannot be emptied completely if ( nwr && nwr < args->fa_buf.l ) memmove(args->fa_buf.s,args->fa_buf.s+nwr,args->fa_buf.l-nwr); args->fa_buf.l -= nwr; return; } // empty the whole buffer if ( nwr == args->fa_buf.l ) { args->fa_buf.l = 0; return; } if ( fwrite(args->fa_buf.s+nwr,1,args->fa_buf.l - nwr,args->fp_out) != args->fa_buf.l - nwr ) error("Could not write: %s\n", args->output_fname); if ( fwrite("\n",1,1,args->fp_out) != 1 ) error("Could not write: %s\n", args->output_fname); args->fa_ori_pos += args->fa_buf.l - nwr - args->fa_mod_off; args->fa_mod_off = 0; args->fa_buf.l = 0; } static void apply_absent(args_t *args, hts_pos_t pos) { if ( !args->fa_buf.l || pos <= args->fa_frz_pos + 1 || pos <= args->fa_ori_pos ) return; int ie = pos && pos - args->fa_ori_pos + args->fa_mod_off < args->fa_buf.l ? pos - args->fa_ori_pos + args->fa_mod_off : args->fa_buf.l; int ib = args->fa_frz_mod < 0 ? 0 : args->fa_frz_mod; int i; for (i=ib; ifa_buf.s[i] = args->absent_allele; } static void freeze_ref(args_t *args, bcf1_t *rec) { if ( args->fa_frz_pos >= rec->pos + rec->rlen - 1 ) return; args->fa_frz_pos = rec->pos + rec->rlen - 1; args->fa_frz_mod = rec->pos - args->fa_ori_pos + args->fa_mod_off + rec->rlen; } static char *mark_del(char *ref, int rlen, char *alt, int mark) { char *out = malloc(rlen+1); int i; if ( alt ) { int nalt = strlen(alt); for (i=0; i { int nref = strlen(ref); for (i=0; in_allele, &args->miupac_als, &args->iupac_als, 0); for (i=0; imiupac_als; i++) args->iupac_als[i] = 0; } static int iupac_add_gt(args_t *args, bcf1_t *rec, uint8_t *gt, int ngt) { int i, is_set = 0; for (i=0; i= rec->n_allele ) error("Invalid VCF, too few ALT alleles at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); args->iupac_als[ial] = 1; is_set = 1; } return is_set; } static int iupac_set_allele(args_t *args, bcf1_t *rec) { int i,j, max_len = 0, alt_len = 0, ialt = -1, fallback_alt = -1; for (i=0; in_allele; i++) { if ( !args->iupac_als[i] ) continue; if ( fallback_alt <=0 ) fallback_alt = i; int l = strlen(rec->d.allele[i]); for (j=0; jd.allele[i][j]) < 0 ) break; if ( jmax_len ) { hts_resize(uint8_t, l, &args->miupac_bitmask, &args->iupac_bitmask, HTS_RESIZE_CLEAR); for (j=max_len; jiupac_bitmask[j] = 0; max_len = l; } if ( i>0 && l>alt_len ) { alt_len = l; ialt = i; } for (j=0; jiupac_bitmask[j] |= iupac2bitmask(rec->d.allele[i][j]); } if ( alt_len > 0 ) { for (j=0; jd.allele[ialt][j] = bitmask2iupac(args->iupac_bitmask[j]); return ialt; } if ( fallback_alt >= 0 ) return fallback_alt; return ialt; } static void apply_variant(args_t *args, bcf1_t *rec) { static int warned_haplotype = 0; if ( args->absent_allele ) apply_absent(args, rec->pos); if ( rec->n_allele==1 && !args->missing_allele && !args->absent_allele ) { return; } int i,j; if ( args->mask ) { char *chr = (char*)bcf_hdr_id2name(args->hdr,args->rid); int start = rec->pos; int end = rec->pos + rec->rlen - 1; for (i=0; inmask; i++) { mask_t *mask = &args->mask[i]; if ( MASK_SKIP(mask) && regidx_overlap(mask->idx, chr,start,end,NULL) ) return; } } int ialt = 1; // the alternate allele if ( args->iupac_GTs ) { bcf_unpack(rec, BCF_UN_FMT); bcf_fmt_t *fmt = bcf_get_fmt(args->hdr, rec, "GT"); if ( !fmt ) return; if ( fmt->type!=BCF_BT_INT8 ) error("Todo: GT field represented with BCF_BT_INT8, too many alleles at %s:%"PRId64"?\n",bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); ialt = -1; int is_set = 0; iupac_init(args,rec); for (i=0; ismpl->n; i++) { uint8_t *ptr = fmt->p + fmt->size*args->smpl->idx[i]; is_set += iupac_add_gt(args, rec, ptr, fmt->n); } if ( !is_set && !args->missing_allele ) return; if ( is_set ) ialt = iupac_set_allele(args, rec); } else if ( args->isample >= 0 ) { bcf_unpack(rec, BCF_UN_FMT); bcf_fmt_t *fmt = bcf_get_fmt(args->hdr, rec, "GT"); if ( !fmt ) return; if ( fmt->type!=BCF_BT_INT8 ) error("Todo: GT field represented with BCF_BT_INT8, too many alleles at %s:%"PRId64"?\n",bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); uint8_t *ptr = fmt->p + fmt->size*args->isample; enum { use_hap, use_iupac, pick_one } action = use_hap; if ( args->allele==PICK_IUPAC ) { if ( !args->haplotype ) action = use_iupac; if ( !bcf_gt_is_phased(ptr[0]) && !bcf_gt_is_phased(ptr[fmt->n-1]) ) action = use_iupac; } else if ( args->output_iupac ) action = use_iupac; else if ( !args->haplotype ) action = pick_one; if ( action==use_hap ) { if ( args->haplotype > fmt->n ) { if ( bcf_gt_is_missing(ptr[fmt->n-1]) || bcf_gt_is_missing(ptr[0]) ) { if ( !args->missing_allele ) return; ialt = -1; } else { if ( !warned_haplotype ) { fprintf(stderr, "Can't apply %d-th haplotype at %s:%"PRId64". (This warning is printed only once.)\n", args->haplotype,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); warned_haplotype = 1; } return; } } else { ialt = (int8_t)ptr[args->haplotype-1]; if ( bcf_gt_is_missing(ialt) || ialt==bcf_int8_vector_end ) { if ( !args->missing_allele ) return; ialt = -1; } else ialt = bcf_gt_allele(ialt); } } else if ( action==use_iupac ) { ialt = -1; iupac_init(args,rec); int is_set = iupac_add_gt(args, rec, ptr, fmt->n); if ( !is_set && !args->missing_allele ) return; if ( is_set ) ialt = iupac_set_allele(args, rec); } else { int is_hom = 1; for (i=0; in; i++) { if ( bcf_gt_is_missing(ptr[i]) ) { if ( !args->missing_allele ) return; // ignore missing or half-missing genotypes ialt = -1; break; } if ( ptr[i]==(uint8_t)bcf_int8_vector_end ) break; ialt = bcf_gt_allele(ptr[i]); if ( i>0 && ialt!=bcf_gt_allele(ptr[i-1]) ) { is_hom = 0; break; } } if ( !is_hom ) { int prev_len = 0, jalt; for (i=0; in; i++) { if ( ptr[i]==(uint8_t)bcf_int8_vector_end ) break; jalt = bcf_gt_allele(ptr[i]); if ( rec->n_allele <= jalt ) error("Broken VCF, too few alts at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); if ( args->allele & (PICK_LONG|PICK_SHORT) ) { int len = jalt==0 ? rec->rlen : strlen(rec->d.allele[jalt]); if ( i==0 ) ialt = jalt, prev_len = len; else if ( len == prev_len ) { if ( args->allele & PICK_REF && jalt==0 ) ialt = jalt, prev_len = len; else if ( args->allele & PICK_ALT && ialt==0 ) ialt = jalt, prev_len = len; } else if ( args->allele & PICK_LONG && len > prev_len ) ialt = jalt, prev_len = len; else if ( args->allele & PICK_SHORT && len < prev_len ) ialt = jalt, prev_len = len; } else { if ( args->allele & PICK_REF && jalt==0 ) ialt = jalt; else if ( args->allele & PICK_ALT && ialt==0 ) ialt = jalt; } } } } if ( !ialt ) { // ref allele if ( args->absent_allele ) freeze_ref(args,rec); return; } if ( rec->n_allele <= ialt ) error("Broken VCF, too few alts at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); } else if ( args->output_iupac && rec->n_allele>1 ) { int ialt, alen = 0, mlen = 0; for (i=0; in_allele; i++) { int l = strlen(rec->d.allele[i]); for (j=0; jd.allele[i][j]) < 0 ) break; if ( j mlen ) { hts_expand(uint8_t,l,args->miupac_bitmask,args->iupac_bitmask); for (j=mlen; jiupac_bitmask[j] = 0; mlen = l; } if ( i>0 && l>alen ) { alen = l; ialt = i; } for (j=0; jiupac_bitmask[j] |= iupac2bitmask(rec->d.allele[i][j]); } if ( alen > 0 ) for (j=0; jd.allele[ialt][j] = bitmask2iupac(args->iupac_bitmask[j]); else ialt = 1; } if ( rec->n_allele==1 && ialt!=-1 ) { // non-missing reference if ( args->absent_allele ) freeze_ref(args,rec); return; } if ( ialt==-1 ) { char alleles[4]; alleles[0] = rec->d.allele[0][0]; alleles[1] = ','; alleles[2] = args->missing_allele; alleles[3] = 0; bcf_update_alleles_str(args->hdr, rec, alleles); ialt = 1; } // For some variant types POS+REF refer to the base *before* the event; in such case set trim_beg int trim_beg = 0; int var_type = bcf_get_variant_type(rec,ialt); int var_len = rec->d.var[ialt].n; if ( var_type & VCF_INDEL ) { // normally indel starts one base after, but not if the first base of the fa reference is deleted if ( rec->d.allele[0][0] == rec->d.allele[ialt][0] ) trim_beg = 1; else trim_beg = 0; } else if ( (var_type & VCF_OTHER) && !strcasecmp(rec->d.allele[ialt],"") ) { trim_beg = 1; var_len = 1 - rec->rlen; } else if ( (var_type & VCF_OTHER) && !strncasecmp(rec->d.allele[ialt],"pos <= args->fa_frz_pos && rec->pos + rec->rlen - 1 > args->fa_frz_pos ) { // Applying the reference allele which overlaps a previous deletion. If we are here, it // means it goes beyond the freezed position, hence the record can be trimmed and moved // forward int ntrim = args->fa_frz_pos - rec->pos + 1; int nref = strlen(rec->d.allele[0]); assert( ntrim < nref ); rec->pos += ntrim; rec->rlen -= ntrim; memmove(rec->d.allele[0],rec->d.allele[0]+ntrim,nref-ntrim); rec->d.allele[0][nref-ntrim] = 0; } if ( rec->pos <= args->fa_frz_pos ) { // Can be still OK iff this is an insertion (and which does not follow another insertion, see #888). // This still may not be enough for more complicated cases with multiple duplicate positions // and other types in between. In such case let the user normalize the VCF and remove duplicates. int overlap = 0; if ( rec->pos < args->fa_frz_pos || !trim_beg || var_len==0 || args->prev_is_insert ) overlap = 1; if ( overlap ) { fprintf(stderr,"The site %s:%"PRId64" overlaps with another variant, skipping...\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); return; } } char *ref_allele = rec->d.allele[0]; char *alt_allele = rec->d.allele[ialt]; int rmme_alt = 0; int len_diff = 0, alen = 0; int idx = rec->pos - args->fa_ori_pos + args->fa_mod_off; // position of the variant within the modified fasta sequence if ( idx<0 ) { if ( alt_allele[0]=='<' ) // symbolic allele { rec->pos -= idx + 1; rec->rlen += idx + 1; idx = -1; } else if ( strlen(ref_allele) < -idx ) // the ref allele is shorter but overlaps the fa sequence? This should never happen { assert(0); fprintf(stderr,"Warning: ignoring overlapping variant starting at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); return; } else if ( strlen(alt_allele) > -idx ) // the ref allele overlaps the fa and so does the alt allele { rec->pos -= idx; rec->rlen += idx; ref_allele -= idx; alt_allele -= idx; idx = 0; } else // the ref allele overlaps the fa but alt allele does not: trim to leave one base before { rec->pos -= idx + 1; rec->rlen += idx + 1; ref_allele -= idx + 1; alt_allele += strlen(alt_allele) - 1; idx = -1; } } if ( rec->rlen > args->fa_buf.l - idx ) { rec->rlen = args->fa_buf.l - idx; if ( alt_allele[0]!='<' ) { alen = strlen(alt_allele); if ( alen > rec->rlen ) { fprintf(stderr,"Warning: trimming variant \"%s\" starting at %s:%"PRId64"\n", alt_allele,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); alt_allele[rec->rlen] = 0; } } } // the variant is beyond the available fasta sequence if ( idx>0 && idx>=args->fa_buf.l ) return; // sanity check the reference base if ( alt_allele[0]=='<' ) { // TODO: symbolic deletions probably need more work above with PICK_SHORT|PICK_LONG if ( strcasecmp(alt_allele,"") && strcasecmp(alt_allele,"<*>") && strcasecmp(alt_allele,"") ) error("Symbolic alleles other than , <*> or are currently not supported, e.g. \"%s\" at %s:%"PRId64".\n" "Please use filtering expressions to exclude such sites, for example by running with: -e 'ALT~\"<.*>\"'\n", alt_allele,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); if ( !strcasecmp(alt_allele,"") ) { static int multibase_ref_del_warned = 0; if ( ref_allele[1]!=0 && !multibase_ref_del_warned ) { fprintf(stderr, "Warning: one REF base is expected with , assuming the actual deletion starts at POS+1 at %s:%"PRId64".\n" " (This warning is printed only once.)\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); multibase_ref_del_warned = 1; } if ( args->mark_del ) // insert dashes instead of delete sequence { alt_allele = mark_del(ref_allele, rec->rlen, NULL, args->mark_del); alen = rec->rlen; len_diff = 0; rmme_alt = 1; } else { len_diff = 1-rec->rlen; alt_allele = ref_allele; // according to VCF spec, the first REF base must precede the event alen = 1; } } else { // <*> or .. gVCF, evidence for the reference allele throughout the whole block freeze_ref(args,rec); return; } } else if ( idx>=0 && strncasecmp(ref_allele,args->fa_buf.s+idx,rec->rlen) ) { // This is hacky, handle a special case: if SNP or an insert follows a deletion (AAC>A, C>CAA), // the reference base in fa_buf is lost and the check fails. We do not keep a buffer // with the original sequence as it should not be necessary, we should encounter max // one base overlap int fail = 1; if ( args->prev_base_pos==rec->pos && toupper(ref_allele[0])==toupper(args->prev_base) ) { if ( rec->rlen==1 ) fail = 0; else if ( !strncasecmp(ref_allele+1,args->fa_buf.s+idx+1,rec->rlen-1) ) fail = 0; } if ( fail ) { char tmp = 0; if ( args->fa_buf.l - idx > rec->rlen ) { tmp = args->fa_buf.s[idx+rec->rlen]; args->fa_buf.s[idx+rec->rlen] = 0; } error( "The fasta sequence does not match the REF allele at %s:%"PRId64":\n" " REF .vcf: [%s]\n" " ALT .vcf: [%s]\n" " REF .fa : [%s]%c%s\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1, ref_allele, alt_allele, args->fa_buf.s+idx, tmp?tmp:' ',tmp?args->fa_buf.s+idx+rec->rlen+1:"" ); } alen = strlen(alt_allele); len_diff = alen - rec->rlen; if ( args->mark_del && len_diff<0 ) { alt_allele = mark_del(ref_allele, rec->rlen, alt_allele, args->mark_del); alen = rec->rlen; len_diff = 0; rmme_alt = 1; } } else { alen = strlen(alt_allele); len_diff = alen - rec->rlen; if ( args->mark_del && len_diff<0 ) { alt_allele = mark_del(ref_allele, rec->rlen, alt_allele, args->mark_del); alen = rec->rlen; len_diff = 0; rmme_alt = 1; } } int safe_idx = idx<0 ? 0 : idx; // idx can be negative in case of overlapping deletion args->fa_case = toupper(args->fa_buf.s[safe_idx])==args->fa_buf.s[safe_idx] ? TO_UPPER : TO_LOWER; if ( args->fa_case==TO_UPPER ) for (i=0; imark_ins && len_diff>0 ) mark_ins(ref_allele, alt_allele, args->mark_ins); if ( args->mark_snv ) mark_snv(ref_allele, alt_allele, args->mark_snv); if ( len_diff <= 0 ) { // deletion or same size event assert( args->fa_buf.l >= idx+rec->rlen ); args->prev_base = args->fa_buf.s[idx+rec->rlen-1]; args->prev_base_pos = rec->pos + rec->rlen - 1; args->prev_is_insert = 0; args->fa_frz_mod = idx + alen; for (i=trim_beg; ifa_buf.s[idx+i] = alt_allele[i]; if ( len_diff ) memmove(args->fa_buf.s+idx+alen,args->fa_buf.s+idx+rec->rlen,args->fa_buf.l-idx-rec->rlen); } else { args->prev_is_insert = 1; args->prev_base_pos = rec->pos; // insertion ks_resize(&args->fa_buf, args->fa_buf.l + len_diff); memmove(args->fa_buf.s + idx + rec->rlen + len_diff, args->fa_buf.s + idx + rec->rlen, args->fa_buf.l - idx - rec->rlen); // This can get tricky, make sure the bases unchanged by the insertion do not overwrite preceding variants. // For example, here we want to get TAA: // POS REF ALT // 1 C T // 1 C CAA int ibeg = 0; while ( ibegpos + ibeg <= args->prev_base_pos ) ibeg++; for (i=ibeg; ifa_buf.s[idx+i] = alt_allele[i]; args->fa_frz_mod = idx + alen - ibeg + 1; } if (args->chain && len_diff != 0) { // If first nucleotide of both REF and ALT are the same... (indels typically include the nucleotide before the variant) if ( strncasecmp(ref_allele,alt_allele,1) == 0) { // ...extend the block by 1 bp: start is 1 bp further and alleles are 1 bp shorter push_chain_gap(args->chain, rec->pos + 1, rec->rlen - 1, rec->pos + 1 + args->fa_mod_off, alen - 1); } else { // otherwise, just the coordinates of the variant as given push_chain_gap(args->chain, rec->pos, rec->rlen, rec->pos + args->fa_mod_off, alen); } } args->fa_buf.l += len_diff; args->fa_mod_off += len_diff; args->fa_frz_pos = rec->pos + rec->rlen - 1; args->napplied++; if ( rmme_alt ) free(alt_allele); } static void mask_region(args_t *args, char *seq, int len) { int start = args->fa_src_pos - len; int end = args->fa_src_pos; int i; for (i=0; inmask; i++) { mask_t *mask = &args->mask[i]; if ( !regidx_overlap(mask->idx, args->chr,start,end, mask->itr) ) continue; int idx_start, idx_end, j; while ( regitr_overlap(mask->itr) ) { idx_start = mask->itr->beg - start; idx_end = mask->itr->end - start; if ( idx_start < 0 ) idx_start = 0; if ( idx_end >= len ) idx_end = len - 1; if ( mask->with==MASK_UC ) for (j=idx_start; j<=idx_end; j++) seq[j] = toupper(seq[j]); else if ( mask->with==MASK_LC ) for (j=idx_start; j<=idx_end; j++) seq[j] = tolower(seq[j]); else for (j=idx_start; j<=idx_end; j++) seq[j] = mask->with; } } } static void consensus(args_t *args) { BGZF *fasta = bgzf_open(args->ref_fname, "r"); if ( !fasta ) error("Error reading %s\n", args->ref_fname); kstring_t str = {0,0,0}; while ( bgzf_getline(fasta, '\n', &str) > 0 ) { if ( str.s[0]=='>' ) { // new sequence encountered if ( args->chain ) print_chain(args); // apply all cached variants and variants that might have been missed because of short fasta (see test/consensus.9.*) bcf1_t **rec_ptr = NULL; while ( args->rid>=0 && (rec_ptr = next_vcf_line(args)) ) { bcf1_t *rec = *rec_ptr; if ( rec->rid!=args->rid || ( args->fa_end_pos && rec->pos > args->fa_end_pos ) ) break; apply_variant(args, rec); } if ( args->absent_allele ) { int pos = 0; if ( args->vcf_rbuf.n && args->vcf_buf[args->vcf_rbuf.f]->rid==args->rid ) pos = args->vcf_buf[args->vcf_rbuf.f]->pos; apply_absent(args, pos); } flush_fa_buffer(args, 0); init_region(args, str.s+1); continue; } args->fa_length += str.l; args->fa_src_pos += str.l; // determine if uppercase or lowercase is used in this fasta file if ( args->fa_case==-1 ) args->fa_case = toupper(str.s[0])==str.s[0] ? 1 : 0; if ( args->mask ) mask_region(args, str.s, str.l); kputs(str.s, &args->fa_buf); bcf1_t **rec_ptr = NULL; while ( args->rid>=0 && (rec_ptr = next_vcf_line(args)) ) { bcf1_t *rec = *rec_ptr; // still the same chr and the same region? if not, fasta buf can be flushed if ( rec->rid!=args->rid || ( args->fa_end_pos && rec->pos > args->fa_end_pos ) ) { // save the vcf record until next time and flush unread_vcf_line(args, rec_ptr); rec_ptr = NULL; break; } // is the vcf record well beyond cached fasta buffer? if yes, the buf can be flushed if ( args->fa_ori_pos + args->fa_buf.l - args->fa_mod_off <= rec->pos ) { unread_vcf_line(args, rec_ptr); rec_ptr = NULL; break; } // is the cached fasta buffer full enough? if not, read more fasta, no flushing if ( args->fa_ori_pos + args->fa_buf.l - args->fa_mod_off < rec->pos + rec->rlen ) { unread_vcf_line(args, rec_ptr); break; } apply_variant(args, rec); } if ( !rec_ptr ) { if ( args->absent_allele ) apply_absent(args, args->fa_ori_pos - args->fa_mod_off + args->fa_buf.l); flush_fa_buffer(args, 60); } } bcf1_t **rec_ptr = NULL; while ( args->rid>=0 && (rec_ptr = next_vcf_line(args)) ) { bcf1_t *rec = *rec_ptr; if ( rec->rid!=args->rid ) break; if ( args->fa_end_pos && rec->pos > args->fa_end_pos ) break; if ( args->fa_ori_pos + args->fa_buf.l - args->fa_mod_off <= rec->pos ) break; apply_variant(args, rec); } if (args->chain) print_chain(args); if ( args->absent_allele ) apply_absent(args, HTS_POS_MAX); flush_fa_buffer(args, 0); bgzf_close(fasta); free(str.s); fprintf(stderr,"Applied %d variants\n", args->napplied); } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Create consensus sequence by applying VCF variants to a reference fasta\n"); fprintf(stderr, " file. By default, the program will apply all ALT variants. Using the\n"); fprintf(stderr, " --samples (and, optionally, --haplotype) option will apply genotype\n"); fprintf(stderr, " (or haplotype) calls from FORMAT/GT. The program ignores allelic depth\n"); fprintf(stderr, " information, such as INFO/AD or FORMAT/AD.\n"); fprintf(stderr, "Usage: bcftools consensus [OPTIONS] \n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -c, --chain FILE Write a chain file for liftover\n"); fprintf(stderr, " -a, --absent CHAR Replace positions absent from VCF with CHAR\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -f, --fasta-ref FILE Reference sequence in fasta format\n"); fprintf(stderr, " -H, --haplotype WHICH Choose which allele to use from the FORMAT/GT field, note\n"); fprintf(stderr, " the codes are case-insensitive:\n"); fprintf(stderr, " N: N={1,2,3,..} is the index of the allele from GT, regardless of phasing (e.g. \"2\")\n"); fprintf(stderr, " R: REF allele in het genotypes\n"); fprintf(stderr, " A: ALT allele\n"); fprintf(stderr, " I: IUPAC code for all genotypes\n"); fprintf(stderr, " LR,LA: longer allele and REF/ALT if equal length\n"); fprintf(stderr, " SR,SA: shorter allele and REF/ALT if equal length\n"); fprintf(stderr, " NpIu: index of the allele for phased and IUPAC code for unphased GTs (e.g. \"2pIu\")\n"); fprintf(stderr, " -i, --include EXPR Select sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -I, --iupac-codes Output IUPAC codes based on FORMAT/GT, use -s/-S to subset samples\n"); fprintf(stderr, " --mark-del CHAR Instead of removing sequence, insert character CHAR for deletions\n"); fprintf(stderr, " --mark-ins uc|lc|CHAR Highlight insertions in uppercase (uc), lowercase (lc), or use CHAR, leaving the rest as is\n"); fprintf(stderr, " --mark-snv uc|lc|CHAR Highlight substitutions in uppercase (uc), lowercase (lc), or use CHAR, leaving the rest as is\n"); fprintf(stderr, " -m, --mask FILE Replace regions according to the next --mask-with option. The default is --mask-with N\n"); fprintf(stderr, " --mask-with CHAR|uc|lc Replace with CHAR (skips overlapping variants); change to uppercase (uc) or lowercase (lc)\n"); fprintf(stderr, " -M, --missing CHAR Output CHAR instead of skipping a missing genotype \"./.\"\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -p, --prefix STRING Prefix to add to output sequence names\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples LIST Comma-separated list of samples to include, \"-\" to ignore samples and use REF,ALT\n"); fprintf(stderr, " -S, --samples-file FILE File of samples to include\n"); fprintf(stderr, "Examples:\n"); fprintf(stderr, " # Get the consensus for one region. The fasta header lines are then expected\n"); fprintf(stderr, " # in the form \">chr:from-to\".\n"); fprintf(stderr, " samtools faidx ref.fa 8:11870-11890 | bcftools consensus in.vcf.gz > out.fa\n"); fprintf(stderr, "\n"); fprintf(stderr, " # See also http://samtools.github.io/bcftools/howtos/consensus-sequence.html\n"); fprintf(stderr, "\n"); exit(1); } int main_consensus(int argc, char *argv[]) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->regions_overlap = 1; static struct option loptions[] = { {"mark-del",required_argument,NULL,1}, {"mark-ins",required_argument,NULL,2}, {"mark-snv",required_argument,NULL,3}, {"mask-with",1,0,4}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"sample",1,0,'s'}, {"samples",1,0,'s'}, {"samples-file",1,0,'S'}, {"iupac-codes",0,0,'I'}, {"haplotype",1,0,'H'}, {"output",1,0,'o'}, {"fasta-ref",1,0,'f'}, {"mask",1,0,'m'}, {"missing",1,0,'M'}, {"absent",1,0,'a'}, {"chain",1,0,'c'}, {"prefix",required_argument,0,'p'}, {"regions-overlap",required_argument,0,5}, {0,0,0,0} }; int c; while ((c = getopt_long(argc, argv, "h?s:S:1Ii:e:H:f:o:m:c:M:p:a:",loptions,NULL)) >= 0) { switch (c) { case 1 : args->mark_del = optarg[0]; break; case 2 : if ( !strcasecmp(optarg,"uc") ) args->mark_ins = TO_UPPER; else if ( !strcasecmp(optarg,"lc") ) args->mark_ins = TO_LOWER; else if ( !optarg[1] && optarg[0]>32 && optarg[0]<127 ) args->mark_ins = optarg[0]; else error("The argument is not recognised: --mark-ins %s\n",optarg); break; case 3 : if ( !strcasecmp(optarg,"uc") ) args->mark_snv = TO_UPPER; else if ( !strcasecmp(optarg,"lc") ) args->mark_snv = TO_LOWER; else if ( !optarg[1] && optarg[0]>32 && optarg[0]<127 ) args->mark_snv = optarg[0]; else error("The argument is not recognised: --mark-snv %s\n",optarg); break; case 5 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 'p': args->chr_prefix = optarg; break; case 's': args->sample = optarg; break; case 'S': args->sample_fname = optarg; break; case 'o': args->output_fname = optarg; break; case 'I': args->output_iupac = 1; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'f': args->ref_fname = optarg; break; case 'm': add_mask(args,optarg); break; case 4 : add_mask_with(args,optarg); break; case 'a': args->absent_allele = optarg[0]; if ( optarg[1]!=0 ) error("Expected single character with -a, got \"%s\"\n", optarg); break; case 'M': args->missing_allele = optarg[0]; if ( optarg[1]!=0 ) error("Expected single character with -M, got \"%s\"\n", optarg); break; case 'c': args->chain_fname = optarg; break; case 'H': if ( !strcasecmp(optarg,"R") ) args->allele |= PICK_REF; else if ( !strcasecmp(optarg,"A") ) args->allele |= PICK_ALT; else if ( !strcasecmp(optarg,"L") ) args->allele |= PICK_LONG|PICK_REF; else if ( !strcasecmp(optarg,"S") ) args->allele |= PICK_SHORT|PICK_REF; else if ( !strcasecmp(optarg,"LR") ) args->allele |= PICK_LONG|PICK_REF; else if ( !strcasecmp(optarg,"LA") ) args->allele |= PICK_LONG|PICK_ALT; else if ( !strcasecmp(optarg,"SR") ) args->allele |= PICK_SHORT|PICK_REF; else if ( !strcasecmp(optarg,"SA") ) args->allele |= PICK_SHORT|PICK_ALT; else if ( !strcasecmp(optarg,"I") ) args->allele |= PICK_IUPAC; else if ( !strcasecmp(optarg,"1pIu") ) args->allele |= PICK_IUPAC, args->haplotype = 1; else if ( !strcasecmp(optarg,"2pIu") ) args->allele |= PICK_IUPAC, args->haplotype = 2; else { char *tmp; args->haplotype = strtol(optarg, &tmp, 10); if ( tmp==optarg || (*tmp && strcasecmp(tmp,"pIu")) ) error("Error: Could not parse \"--haplotype %s\", expected number of number followed with \"pIu\"\n", optarg); if ( *tmp ) args->allele |= PICK_IUPAC; if ( args->haplotype <=0 ) error("Error: Expected positive integer with --haplotype\n"); } break; default: usage(args); break; } } if ( optind>=argc ) usage(args); args->fname = argv[optind]; if ( !args->ref_fname && !isatty(fileno((FILE *)stdin)) ) args->ref_fname = "-"; if ( !args->ref_fname ) usage(args); init_data(args); consensus(args); destroy_data(args); free(args); return 0; } bcftools-1.21/convert.c000066400000000000000000002071101467060157400151070ustar00rootroot00000000000000/* convert.c -- functions for converting between VCF/BCF and related formats. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #define __STDC_FORMAT_MACROS #include #include #include #include #include #include #include #include #include "bcftools.h" #include "variantkey.h" #include "convert.h" #include "filter.h" #define T_CHROM 1 #define T_POS 2 #define T_ID 3 #define T_REF 4 #define T_ALT 5 #define T_QUAL 6 #define T_FILTER 7 #define T_INFO 8 #define T_FORMAT 9 #define T_SAMPLE 10 #define T_SEP 11 #define T_IS_TS 12 #define T_TYPE 13 #define T_MASK 14 #define T_GT 15 #define T_TGT 16 #define T_LINE 17 #define T_CHROM_POS_ID 18 // not publicly advertised #define T_GT_TO_PROB3 19 // not publicly advertised #define T_PL_TO_PROB3 20 // not publicly advertised #define T_GP_TO_PROB3 21 // not publicly advertised #define T_FIRST_ALT 22 // not publicly advertised #define T_IUPAC_GT 23 #define T_GT_TO_HAP 24 // not publicly advertised #define T_GT_TO_HAP2 25 // not publicly advertised #define T_TBCSQ 26 #define T_END 27 #define T_POS0 28 #define T_END0 29 #define T_RSX 30 // RSID HEX #define T_VKX 31 // VARIANTKEY HEX #define T_PBINOM 32 #define T_NPASS 33 typedef struct _fmt_t { int type, id, is_gt_field, ready, subscript; char *key; bcf_fmt_t *fmt; void *usr; // user data (optional) void (*handler)(convert_t *, bcf1_t *, struct _fmt_t *, int, kstring_t *); void (*destroy)(void*); // clean user data (optional) } fmt_t; struct _convert_t { fmt_t *fmt; int nfmt, mfmt; int nsamples, *samples; bcf_hdr_t *header; int max_unpack; char *format_str; bcf_srs_t *readers; // required only for %MASK int nreaders; void *dat; int ndat; char *undef_info_tag; void *used_tags_hash; char **used_tags_list; char *print_filtered; int nused_tags; int allow_undef_tags; int force_newline; int header_samples; int no_hdr_indices; uint8_t **subset_samples; }; typedef struct { kstring_t hap1,hap2; char **str; int n, m; } bcsq_t; static void process_chrom(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(convert->header->id[BCF_DT_CTG][line->rid].key, str); } static void process_pos(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos+1, str); } static void process_pos0(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos, str); } static void process_end(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos+line->rlen, str); } static void process_end0(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos+line->rlen-1, str); } static void process_id(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(line->d.id, str); } static void process_ref(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(line->d.allele[0], str); } static void process_alt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int i; if ( line->n_allele==1 ) { kputc('.', str); return; } if ( fmt->subscript>=0 ) { if ( line->n_allele > fmt->subscript+1 ) kputs(line->d.allele[fmt->subscript+1], str); else kputc('.', str); return; } for (i=1; in_allele; i++) { if ( i>1 ) kputc(',', str); kputs(line->d.allele[i], str); } } static void process_first_alt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( line->n_allele==1 ) kputc('.', str); else kputs(line->d.allele[1], str); } static void process_qual(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( bcf_float_is_missing(line->qual) ) kputc('.', str); else kputd(line->qual, str); } static void process_filter(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int i; if ( line->d.n_flt ) { for (i=0; id.n_flt; i++) { if (i) kputc(';', str); kputs(convert->header->id[BCF_DT_ID][line->d.flt[i]].key, str); } } else kputc('.', str); } static inline int32_t bcf_array_ivalue(uint8_t *bcf_array, int type, int idx) { if ( type==BCF_BT_INT8 ) { int8_t val = le_to_i8(&bcf_array[idx * sizeof(val)]); if ( val==bcf_int8_missing ) return bcf_int32_missing; if ( val==bcf_int8_vector_end ) return bcf_int32_vector_end; return val; } if ( type==BCF_BT_INT16 ) { int16_t val = le_to_i16(&bcf_array[idx * sizeof(val)]); if ( val==bcf_int16_missing ) return bcf_int32_missing; if ( val==bcf_int16_vector_end ) return bcf_int32_vector_end; return val; } return le_to_i32(&bcf_array[idx * sizeof(int32_t)]); } static inline void _copy_field(char *src, uint32_t len, int idx, kstring_t *str) { int n = 0, ibeg = 0; while ( src[ibeg] && ibegibeg ) kputsn(src+ibeg, iend-ibeg, str); else kputc('.', str); } static void process_info(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int i; if ( !fmt->key ) // the whole INFO column { int first = 1; for (i=0; in_info; i++) { bcf_info_t *inf = &line->d.info[i]; if ( !inf->vptr ) continue; if ( !first ) kputc(';', str); first = 0; if ( inf->key >= convert->header->n[BCF_DT_ID] ) continue; kputs(convert->header->id[BCF_DT_ID][inf->key].key, str); if ( inf->len <= 0 ) continue; kputc('=', str); if ( inf->len == 1 ) { switch (inf->type) { case BCF_BT_INT8: if ( inf->v1.i==bcf_int8_missing ) kputc('.', str); else kputw(inf->v1.i, str); break; case BCF_BT_INT16: if ( inf->v1.i==bcf_int16_missing ) kputc('.', str); else kputw(inf->v1.i, str); break; case BCF_BT_INT32: if ( inf->v1.i==bcf_int32_missing ) kputc('.', str); else kputw(inf->v1.i, str); break; case BCF_BT_FLOAT: if ( bcf_float_is_missing(inf->v1.f) ) kputc('.', str); else kputd(inf->v1.f, str); break; case BCF_BT_CHAR: kputc(inf->v1.i, str); break; default: error("Unexpected type %d", inf->type); break; } } else bcf_fmt_array(str, inf->len, inf->type, inf->vptr); } if ( first ) kputc('.', str); return; } if ( fmt->id<0 ) { kputc('.', str); return; } for (i=0; in_info; i++) if ( line->d.info[i].key == fmt->id ) break; // output "." if the tag is not present if ( i==line->n_info ) { kputc('.', str); return; } bcf_info_t *info = &line->d.info[i]; // if this is a flag, output 1 if ( info->len <=0 ) { kputc('1', str); return; } if ( info->len == 1 ) { switch (info->type) { case BCF_BT_INT8: if ( info->v1.i==bcf_int8_missing ) kputc('.', str); else kputw(info->v1.i, str); break; case BCF_BT_INT16: if ( info->v1.i==bcf_int16_missing ) kputc('.', str); else kputw(info->v1.i, str); break; case BCF_BT_INT32: if ( info->v1.i==bcf_int32_missing ) kputc('.', str); else kputw(info->v1.i, str); break; case BCF_BT_FLOAT: if ( bcf_float_is_missing(info->v1.f) ) kputc('.', str); else kputd(info->v1.f, str); break; case BCF_BT_CHAR: kputc(info->v1.i, str); break; default: fprintf(stderr,"todo: type %d\n", info->type); exit(1); break; } } else if ( fmt->subscript >=0 ) { if ( info->len <= fmt->subscript ) { kputc('.', str); return; } #define BRANCH(type_t, convert, is_missing, is_vector_end, kprint) { \ type_t val = convert(&info->vptr[fmt->subscript * sizeof(type_t)]); \ if ( is_missing || is_vector_end ) kputc('.',str); \ else kprint; \ } switch (info->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, kputw(val, str)); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, kputw(val, str)); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, val==bcf_int32_missing, val==bcf_int32_vector_end, kputw(val, str)); break; case BCF_BT_FLOAT: BRANCH(float, le_to_float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), kputd(val, str)); break; case BCF_BT_CHAR: _copy_field((char*)info->vptr, info->vptr_len, fmt->subscript, str); break; default: fprintf(stderr,"todo: type %d\n", info->type); exit(1); break; } #undef BRANCH } else bcf_fmt_array(str, info->len, info->type, info->vptr); } static void init_format(convert_t *convert, bcf1_t *line, fmt_t *fmt) { fmt->id = bcf_hdr_id2int(convert->header, BCF_DT_ID, fmt->key); if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,fmt->id) ) fmt->id = -1; fmt->fmt = NULL; if ( fmt->id >= 0 ) { int i; for (i=0; i<(int)line->n_fmt; i++) if ( line->d.fmt[i].id==fmt->id ) { fmt->fmt = &line->d.fmt[i]; break; } } else if ( !convert->allow_undef_tags ) error("Error: no such tag defined in the VCF header: FORMAT/%s\n", fmt->key); fmt->ready = 1; } static void process_complete_format(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( convert->nsamples ) { int i,j; if ( line->n_fmt) { int gt_i = -1; bcf_fmt_t *fmt = line->d.fmt; int first = 1; for (i=0; i<(int)line->n_fmt; i++) { if ( !fmt[i].p || fmt[i].id<0 ) continue; if ( !first ) kputc(':', str); first = 0; kputs(convert->header->id[BCF_DT_ID][fmt[i].id].key, str); if ( strcmp(convert->header->id[BCF_DT_ID][fmt[i].id].key, "GT") == 0) gt_i = i; } if ( first ) kputc('.', str); for (j=0; jnsamples; j++) { kputc('\t', str); first = 1; for (i=0; i<(int)line->n_fmt; i++) { bcf_fmt_t *f = &fmt[i]; if ( !f->p ) continue; if ( !first ) kputc(':', str); first = 0; if (gt_i == i) bcf_format_gt(f,convert->samples[j],str); else bcf_fmt_array(str, f->n, f->type, f->p + convert->samples[j] * f->size); } if ( first ) kputc('.', str); } } else for (j=0; j<=line->n_sample; j++) kputs("\t.", str); } else kputc('.',str); } static void process_format(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( !fmt->ready ) init_format(convert, line, fmt); if ( fmt->fmt==NULL ) { kputc('.', str); return; } else if ( fmt->subscript >=0 ) { if ( fmt->fmt->n <= fmt->subscript ) { kputc('.', str); return; } if ( fmt->fmt->type == BCF_BT_FLOAT ) { uint8_t *ptr = fmt->fmt->p + isample*fmt->fmt->size; float val = le_to_float(&ptr[fmt->subscript * sizeof(float)]); if ( bcf_float_is_missing(val) || bcf_float_is_vector_end(val) ) kputc('.', str); else kputd(val, str); } else if ( fmt->fmt->type != BCF_BT_CHAR ) { int32_t ival = bcf_array_ivalue(fmt->fmt->p+isample*fmt->fmt->size,fmt->fmt->type,fmt->subscript); if ( ival==bcf_int32_missing || ival==bcf_int32_vector_end ) kputc('.', str); else kputw(ival, str); } else if ( fmt->fmt->type == BCF_BT_CHAR ) _copy_field((char*)(fmt->fmt->p + isample*fmt->fmt->size), fmt->fmt->size, fmt->subscript, str); else error("TODO: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt->fmt->type); } else bcf_fmt_array(str, fmt->fmt->n, fmt->fmt->type, fmt->fmt->p + isample*fmt->fmt->size); } static void process_gt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( !fmt->ready ) init_format(convert, line, fmt); if ( fmt->fmt==NULL ) { kputc('.', str); return; } bcf_format_gt(fmt->fmt, isample, str); } static void process_tgt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( !fmt->ready ) init_format(convert, line, fmt); if ( fmt->fmt==NULL ) { kputc('.', str); return; } assert( fmt->fmt->type==BCF_BT_INT8 ); int l; int8_t *x = (int8_t*)(fmt->fmt->p + isample*fmt->fmt->size); // FIXME: does not work with n_alt >= 64 for (l = 0; l < fmt->fmt->n && x[l] != bcf_int8_vector_end; ++l) { if (l) kputc("/|"[x[l]&1], str); if (x[l]>>1) { int ial = (x[l]>>1) - 1; kputs(line->d.allele[ial], str); } else kputc('.', str); } if (l == 0) kputc('.', str); } static void destroy_tbcsq(void *usr) { if ( !usr ) return; bcsq_t *csq = (bcsq_t*) usr; free(csq->hap1.s); free(csq->hap2.s); if ( csq->n ) free(csq->str[0]); free(csq->str); free(csq); } static void process_tbcsq(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( !fmt->ready ) { init_format(convert, line, fmt); bcsq_t *csq; if ( fmt->usr ) { csq = (bcsq_t*) fmt->usr; if ( csq->n ) free(csq->str[0]); csq->n = 0; } else csq = (bcsq_t*) calloc(1,sizeof(bcsq_t)); fmt->usr = csq; int i=0, len = 0; char *tmp = NULL; if ( bcf_get_info_string(convert->header,line,fmt->key,&tmp,&len)<0 ) { csq->n = 0; return; } do { csq->n++; hts_expand(char*, csq->n, csq->m, csq->str); csq->str[ csq->n-1 ] = tmp + i; while ( iusr; if ( fmt->fmt==NULL || !csq->n ) return; csq->hap1.l = 0; csq->hap2.l = 0; int mask = fmt->subscript==0 ? 3 : 1; // merge both haplotypes if subscript==0 #define BRANCH(type_t, convert, nbits) { \ uint8_t *x = fmt->fmt->p + isample*fmt->fmt->size; \ int i,j; \ if ( fmt->subscript<=0 || fmt->subscript==1 ) \ { \ for (j=0; j < fmt->fmt->n; j++) \ { \ type_t val = convert(&x[j * sizeof(type_t)]); \ if ( !val ) continue; \ for (i=0; istr[(j*30+i)/2], &csq->hap1); kputc_(',', &csq->hap1); } \ } \ } \ if ( fmt->subscript<0 || fmt->subscript==2 ) \ { \ for (j=0; j < fmt->fmt->n; j++) \ { \ type_t val = convert(&x[j * sizeof(type_t)]); \ if ( !val ) continue; \ for (i=1; istr[(j*30+i)/2], &csq->hap2); kputc_(',', &csq->hap2); } \ } \ } \ } switch (fmt->fmt->type) { case BCF_BT_INT8: BRANCH(uint8_t, le_to_u8, 8); break; case BCF_BT_INT16: BRANCH(uint16_t, le_to_u16, 16); break; case BCF_BT_INT32: BRANCH(uint32_t, le_to_u32, 30); break; // 2 bits unused to account for the reserved BCF values default: error("Unexpected type: %d\n", fmt->fmt->type); exit(1); break; } #undef BRANCH if ( !csq->hap1.l && !csq->hap2.l ) return; if ( csq->hap1.l ) csq->hap1.s[--csq->hap1.l] = 0; if ( csq->hap2.l ) csq->hap2.s[--csq->hap2.l] = 0; if ( fmt->subscript<0 ) { kputs(csq->hap1.l?csq->hap1.s:".", str); kputc_('\t', str); kputs(csq->hap2.l?csq->hap2.s:".", str); } else if ( fmt->subscript<2 ) kputs(csq->hap1.l?csq->hap1.s:".", str); else kputs(csq->hap2.l?csq->hap2.s:".", str); } static void init_format_iupac(convert_t *convert, bcf1_t *line, fmt_t *fmt) { init_format(convert, line, fmt); if ( fmt->fmt==NULL ) return; // Init mapping between alleles and IUPAC table hts_expand(uint8_t, line->n_allele, convert->ndat, convert->dat); int8_t *dat = (int8_t*)convert->dat; int i; for (i=0; in_allele; i++) { if ( line->d.allele[i][1] ) dat[i] = -1; else { switch (line->d.allele[i][0]) { case 'A': dat[i] = 0; break; case 'C': dat[i] = 1; break; case 'G': dat[i] = 2; break; case 'T': dat[i] = 3; break; case 'a': dat[i] = 0; break; case 'c': dat[i] = 1; break; case 'g': dat[i] = 2; break; case 't': dat[i] = 3; break; default: dat[i] = -1; } } } } static void process_iupac_gt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( !fmt->ready ) init_format_iupac(convert, line, fmt); if ( fmt->fmt==NULL ) { kputc('.', str); return; } assert( fmt->fmt->type==BCF_BT_INT8 ); static const char iupac[4][4] = { {'A','M','R','W'},{'M','C','S','Y'},{'R','S','G','K'},{'W','Y','K','T'} }; int8_t *dat = (int8_t*)convert->dat; int8_t *x = (int8_t*)(fmt->fmt->p + isample*fmt->fmt->size); // FIXME: does not work with n_alt >= 64 int l = 0; while ( lfmt->n && x[l]!=bcf_int8_vector_end && x[l]!=bcf_int8_missing ) l++; if ( l==2 ) { // diploid int ia = (x[0]>>1) - 1, ib = (x[1]>>1) - 1; if ( ia>=0 && ian_allele && ib>=0 && ibn_allele && dat[ia]>=0 && dat[ib]>=0 ) { kputc(iupac[dat[ia]][dat[ib]], str); return; } } for (l = 0; l < fmt->fmt->n && x[l] != bcf_int8_vector_end; ++l) { if (l) kputc("/|"[x[l]&1], str); if (x[l]>>1) { int ial = (x[l]>>1) - 1; kputs(line->d.allele[ial], str); } else kputc('.', str); } if (l == 0) kputc('.', str); } static void process_sample(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(convert->header->samples[isample], str); } static void process_sep(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if (fmt->key) kputs(fmt->key, str); } static void process_is_ts(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int is_ts = 0; if ( bcf_get_variant_types(line) & (VCF_SNP|VCF_MNP) ) is_ts = abs(bcf_acgt2int(*line->d.allele[0])-bcf_acgt2int(*line->d.allele[1])) == 2 ? 1 : 0; kputc(is_ts ? '1' : '0', str); } static void process_type(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int line_type = bcf_get_variant_types(line); int i = 0; if ( line_type == VCF_REF ) { kputs("REF", str); i++; } if ( line_type & VCF_SNP ) { if (i) kputc(',',str); kputs("SNP", str); i++; } if ( line_type & VCF_MNP ) { if (i) kputc(',',str); kputs("MNP", str); i++; } if ( line_type & VCF_INDEL ) { if (i) kputc(',',str); kputs("INDEL", str); i++; } if ( line_type & VCF_OTHER ) { if (i) kputc(',',str); kputs("OTHER", str); i++; } if ( line_type & VCF_BND ) { if (i) kputc(',',str); kputs("BND", str); i++; } if ( line_type & VCF_OVERLAP ) { if (i) kputc(',',str); kputs("OVERLAP", str); i++; } } static void process_line(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { vcf_format1(convert->header, line, str); if ( str->s[str->l-1]=='\n' ) str->l--; } static void process_chrom_pos_id(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if ( line->d.id[0]!='.' || line->d.id[1] ) { // ID is present kputs(line->d.id, str); } else { // use CHROM:POS instead of ID kputs(convert->header->id[BCF_DT_CTG][line->rid].key, str); kputc(':', str); kputw(line->pos+1, str); } } static void process_gt_to_prob3(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int m,n,i; m = convert->ndat / sizeof(int32_t); n = bcf_get_genotypes(convert->header,line,&convert->dat,&m); convert->ndat = m * sizeof(int32_t); if ( n<=0 ) { // Throw an error or silently proceed? // // for (i=0; insamples; i++) kputs(" 0.33 0.33 0.33", str); // return; error("Error parsing GT tag at %s:%"PRId64"\n", bcf_seqname(convert->header,line),(int64_t) line->pos+1); } n /= convert->nsamples; for (i=0; insamples; i++) { int32_t *ptr = (int32_t*)convert->dat + i*n; int j; for (j=0; jndat / sizeof(int32_t); n = bcf_get_format_int32(convert->header,line,"PL",&convert->dat,&m); convert->ndat = m * sizeof(int32_t); if ( n<=0 ) { // Throw an error or silently proceed? // // for (i=0; insamples; i++) kputs(" 0.33 0.33 0.33", str); // return; error("Error parsing PL tag at %s:%"PRId64"\n", bcf_seqname(convert->header,line),(int64_t) line->pos+1); } n /= convert->nsamples; for (i=0; insamples; i++) { int32_t *ptr = (int32_t*)convert->dat + i*n; int j; float sum = 0; for (j=0; jn_allele ) { // haploid kputc(' ',str); ksprintf(str,"%f",pow(10,-0.1*ptr[0])/sum); kputs(" 0 ", str); ksprintf(str,"%f",pow(10,-0.1*ptr[1])/sum); } else { // diploid kputc(' ',str); ksprintf(str,"%f",pow(10,-0.1*ptr[0])/sum); kputc(' ',str); ksprintf(str,"%f",pow(10,-0.1*ptr[1])/sum); kputc(' ',str); ksprintf(str,"%f",pow(10,-0.1*ptr[2])/sum); } } } static void process_gp_to_prob3(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int m,n,i; m = convert->ndat / sizeof(float); n = bcf_get_format_float(convert->header,line,"GP",&convert->dat,&m); convert->ndat = m * sizeof(float); if ( n<=0 ) { // Throw an error or silently proceed? // // for (i=0; insamples; i++) kputs(" 0.33 0.33 0.33", str); // return; error("Error parsing GP tag at %s:%"PRId64"\n", bcf_seqname(convert->header,line),(int64_t) line->pos+1); } n /= convert->nsamples; for (i=0; insamples; i++) { float *ptr = (float*)convert->dat + i*n; int j; for (j=0; j1 ) error("[%s:%"PRId64":%f] GP value outside range [0,1]; bcftools convert expects the VCF4.3+ spec for the GP field encoding genotype posterior probabilities", bcf_seqname(convert->header,line),(int64_t) line->pos+1,ptr[j]); } if ( j==line->n_allele ) ksprintf(str," %f %f %f",ptr[0],0.,ptr[1]); // haploid else ksprintf(str," %f %f %f",ptr[0],ptr[1],ptr[2]); // diploid } } static void process_gt_to_hap(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { // https://mathgen.stats.ox.ac.uk/impute/impute_v2.html#-known_haps_g // File containing known haplotypes for the study cohort. The format // is the same as the output format from IMPUTE2's -phase option: // five header columns (as in the -g file) followed by two columns // (haplotypes) per individual. Allowed values in the haplotype // columns are 0, 1, and ?. // If your study dataset is fully phased, you can replace the -g file // with a -known_haps_g file. This will cause IMPUTE2 to perform // haploid imputation, although it will still report diploid imputation // probabilities in the main output file. If any genotypes are missing, // they can be marked as '? ?' (two question marks separated by one // space) in the input file. (The program does not allow just one // allele from a diploid genotype to be missing.) If the reference // panels are also phased, IMPUTE2 will perform a single, fast // imputation step rather than its standard MCMC module this is how // the program imputes into pre-phased GWAS haplotypes. // The -known_haps_g file can also be used to specify study // genotypes that are "partially" phased, in the sense that some // genotypes are phased relative to a fixed reference point while // others are not. We anticipate that this will be most useful when // trying to phase resequencing data onto a scaffold of known // haplotypes. To mark a known genotype as unphased, place an // asterisk immediately after each allele, with no space between // the allele (0/1) and the asterisk (*); e.g., "0* 1*" for a // heterozygous genotype of unknown phase. int i, gt_id = bcf_hdr_id2int(convert->header, BCF_DT_ID, "GT"); if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,gt_id) ) error("FORMAT/GT tag not present at %s:%"PRId64"\n", bcf_seqname(convert->header, line),(int64_t) line->pos+1); if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); bcf_fmt_t *fmt_gt = NULL; for (i=0; in_fmt; i++) if ( line->d.fmt[i].id==gt_id ) { fmt_gt = &line->d.fmt[i]; break; } if ( !fmt_gt ) error("FORMAT/GT tag not present at %s:%"PRId64"\n", bcf_seqname(convert->header, line),(int64_t) line->pos+1); // Alloc all memory in advance to avoid kput routines. The biggest allowed allele index is 99 if ( line->n_allele > 100 ) error("Too many alleles (%d) at %s:%"PRId64"\n", line->n_allele, bcf_seqname(convert->header, line),(int64_t) line->pos+1); if ( ks_resize(str, str->l+convert->nsamples*8) != 0 ) error("Could not alloc %" PRIu64 " bytes\n", (uint64_t)(str->l + convert->nsamples*8)); if ( fmt_gt->type!=BCF_BT_INT8 ) // todo: use BRANCH_INT if the VCF is valid error("Uh, too many alleles (%d) or redundant BCF representation at %s:%"PRId64"\n", line->n_allele, bcf_seqname(convert->header, line),(int64_t) line->pos+1); if ( fmt_gt->n!=1 && fmt_gt->n!=2 ) error("Uh, ploidy of %d not supported, see %s:%"PRId64"\n", fmt_gt->n, bcf_seqname(convert->header, line),(int64_t) line->pos+1); int8_t *ptr = ((int8_t*) fmt_gt->p) - fmt_gt->n; for (i=0; insamples; i++) { ptr += fmt_gt->n; if ( fmt_gt->n==1 ) // haploid genotypes { if ( ptr[0]==2 ) /* 0 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } else if ( ptr[0]==bcf_int8_missing ) /* . */ { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } else if ( ptr[0]==4 ) /* 1 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } else { kputw(bcf_gt_allele(ptr[0]),str); str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } } else if ( ptr[0]==2 ) { if ( ptr[1]==3 ) /* 0|0 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; } else if ( ptr[1]==5 ) /* 0|1 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; } else if ( ptr[1]==bcf_int8_vector_end ) /* 0 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } else if ( ptr[1]==2 ) /* 0/0 */ { str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( ptr[1]==4 ) /* 0/1 */ { str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_missing(ptr[1]) ) /* 0/. */ { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_phased(ptr[1]) ) /* 0|x */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = ' '; } else /* 0/x */ { str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = '*'; str->s[str->l++] = ' '; } } else if ( ptr[0]==4 ) { if ( ptr[1]==3 ) /* 1|0 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; } else if ( ptr[1]==5 ) /* 1|1 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; } else if ( ptr[1]==bcf_int8_vector_end ) /* 1 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } else if ( ptr[1]==2 ) /* 1/0 */ { str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( ptr[1]==4 ) /* 1/1 */ { str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_missing(ptr[1]) ) /* 1/. */ { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_phased(ptr[1]) ) /* 1|x */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = ' '; } else /* 1/x */ { str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = '*'; str->s[str->l++] = ' '; } } else if ( bcf_gt_is_missing(ptr[0]) ) { if ( ptr[1]==bcf_int8_vector_end ) { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } else { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } } else if ( ptr[1]==bcf_int8_vector_end ) { /* use REF for something else than first ALT */ str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; } else { kputw(bcf_gt_allele(ptr[0]),str); if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; str->s[str->l++] = ' '; } } str->s[--str->l] = 0; // delete the last space } static void process_gt_to_hap2(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { // same as process_gt_to_hap but converts haploid genotypes into diploid int i, gt_id = bcf_hdr_id2int(convert->header, BCF_DT_ID, "GT"); if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,gt_id) ) error("FORMAT/GT tag not present at %s:%"PRId64"\n", bcf_seqname(convert->header, line),(int64_t) line->pos+1); if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); bcf_fmt_t *fmt_gt = NULL; for (i=0; in_fmt; i++) if ( line->d.fmt[i].id==gt_id ) { fmt_gt = &line->d.fmt[i]; break; } if ( !fmt_gt ) error("FORMAT/GT tag not present at %s:%"PRId64"\n", bcf_seqname(convert->header, line),(int64_t) line->pos+1); // Alloc all memory in advance to avoid kput routines. The biggest allowed allele index is 99 if ( line->n_allele > 100 ) error("Too many alleles (%d) at %s:%"PRId64"\n", line->n_allele, bcf_seqname(convert->header, line),(int64_t) line->pos+1); if ( ks_resize(str, str->l+convert->nsamples*8) != 0 ) error("Could not alloc %" PRIu64 " bytes\n", (uint64_t)(str->l + convert->nsamples*8)); if ( fmt_gt->type!=BCF_BT_INT8 ) // todo: use BRANCH_INT if the VCF is valid error("Uh, too many alleles (%d) or redundant BCF representation at %s:%"PRId64"\n", line->n_allele, bcf_seqname(convert->header, line),(int64_t) line->pos+1); int8_t *ptr = ((int8_t*) fmt_gt->p) - fmt_gt->n; for (i=0; insamples; i++) { ptr += fmt_gt->n; if ( ptr[0]==2 ) { if ( ptr[1]==3 ) /* 0|0 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; } else if ( ptr[1]==5 ) /* 0|1 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; } else if ( ptr[1]==bcf_int8_vector_end ) /* 0 -> 0|0 */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; } else if ( ptr[1]==2 ) /* 0/0 */ { str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( ptr[1]==4 ) /* 0/1 */ { str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_missing(ptr[1]) ) /* 0/. */ { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_phased(ptr[1]) ) /* 0|x */ { str->s[str->l++] = '0'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = ' '; } else /* 0/x */ { str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = '*'; str->s[str->l++] = ' '; } } else if ( ptr[0]==4 ) { if ( ptr[1]==3 ) /* 1|0 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; } else if ( ptr[1]==5 ) /* 1|1 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; } else if ( ptr[1]==bcf_int8_vector_end ) /* 1 -> 1|1 */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; } else if ( ptr[1]==2 ) /* 1/0 */ { str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( ptr[1]==4 ) /* 1/1 */ { str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_missing(ptr[1]) ) /* 1/. */ { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } else if ( bcf_gt_is_phased(ptr[1]) ) /* 1|x */ { str->s[str->l++] = '1'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = ' '; } else /* 1/x */ { str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); str->s[str->l++] = '*'; str->s[str->l++] = ' '; } } else if ( bcf_gt_is_missing(ptr[0]) ) { str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; } else if ( ptr[1]==bcf_int8_vector_end ) { /* use REF for something else than first ALT */ str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; } else { kputw(bcf_gt_allele(ptr[0]),str); if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; str->s[str->l++] = ' '; kputw(bcf_gt_allele(ptr[1]),str); if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; str->s[str->l++] = ' '; } } str->s[--str->l] = 0; // delete the last space } static void process_rsid_hex(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { char *ptr = line->d.id; ptr += 2; // remove 'rs' ksprintf(str, "%08" PRIx32 "", (uint32_t)strtoul(ptr, NULL, 10)); } static void process_variantkey_hex(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { const char *alt = NULL; size_t sizealt = 0; if ( line->n_allele>1 ) { alt = line->d.allele[1]; sizealt = strlen(line->d.allele[1]); } uint64_t vk = variantkey( convert->header->id[BCF_DT_CTG][line->rid].key, strlen(convert->header->id[BCF_DT_CTG][line->rid].key), line->pos, line->d.allele[0], strlen(line->d.allele[0]), alt, sizealt); ksprintf(str, "%016" PRIx64 "", vk); } static void process_npass(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int i, nsmpl = 0; filter_t *flt = (filter_t*) fmt->usr; const uint8_t *smpl; filter_test(flt,line,&smpl); for (i=0; insamples; i++) if ( smpl[i] ) nsmpl++; kputd(nsmpl, str); } static void destroy_npass(void *usr) { filter_destroy((filter_t*)usr); } static void process_pbinom(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { int i; if ( !fmt->ready ) { fmt->fmt = NULL; // AD fmt->usr = NULL; // GT for (i=0; i<(int)line->n_fmt; i++) if ( line->d.fmt[i].id==fmt->id ) { fmt->fmt = &line->d.fmt[i]; break; } // Check that the first field is GT int gt_id = bcf_hdr_id2int(convert->header, BCF_DT_ID, "GT"); if ( !bcf_hdr_idinfo_exists(convert->header, BCF_HL_FMT, fmt->id) ) error("Error: FORMAT/GT is not defined in the header\n"); for (i=0; i<(int)line->n_fmt; i++) if ( line->d.fmt[i].id==gt_id ) { fmt->usr = &line->d.fmt[i]; break; } // it should always be first according to VCF spec, but... if ( fmt->usr && line->d.fmt[i].type!=BCF_BT_INT8 ) // skip sites with many alleles fmt->usr = NULL; fmt->ready = 1; } bcf_fmt_t *gt_fmt = (bcf_fmt_t*) fmt->usr; if ( !fmt->fmt || !gt_fmt || gt_fmt->n!=2 ) goto invalid; int n[2] = {0,0}; int8_t *gt = (int8_t*)(gt_fmt->p + isample*gt_fmt->size); for (i=0; i<2; i++) { if ( bcf_gt_is_missing(gt[i]) || gt[i] == bcf_int8_vector_end ) goto invalid; int al = bcf_gt_allele(gt[i]); if ( al > line->n_allele || al >= fmt->fmt->n ) goto invalid; #define BRANCH(type_t, convert, missing, vector_end) { \ type_t val = convert(&fmt->fmt->p[(al + isample*fmt->fmt->n)*sizeof(type_t)]); \ if ( val==missing || val==vector_end ) goto invalid; \ else n[i] = val; \ } switch (fmt->fmt->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, bcf_int8_missing, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, bcf_int16_missing, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, bcf_int32_missing, bcf_int32_vector_end); break; default: goto invalid; break; } #undef BRANCH } if ( n[0]==n[1] ) kputc(n[0]==0 ? '.':'0', str); else { double pval = calc_binom_two_sided(n[0],n[1],0.5); // convrt to phred if ( pval>=1 ) pval = 0; else pval = -4.34294481903*log(pval); kputd(pval, str); } return; invalid: kputc('.', str); } static void _used_tags_add(convert_t *convert, int type, char *key) { kstring_t str = {0,0,0}; ksprintf(&str,"%s/%s",type==T_INFO?"INFO":"FORMAT",key); khash_str2int_inc(convert->used_tags_hash,str.s); convert->nused_tags++; convert->used_tags_list = (char**)realloc(convert->used_tags_list,sizeof(*convert->used_tags_list)*convert->nused_tags); convert->used_tags_list[convert->nused_tags-1] = str.s; } #define _SET_NON_FORMAT_TAGS(function,key,...) \ if ( !strcmp("CHROM",key) ) { function(__VA_ARGS__, T_CHROM); } \ else if ( !strcmp("POS",key) ) { function(__VA_ARGS__, T_POS); } \ else if ( !strcmp("POS0",key) ) { function(__VA_ARGS__, T_POS0); } \ else if ( !strcmp("END",key) ) { function(__VA_ARGS__, T_END); } \ else if ( !strcmp("END0",key) ) { function(__VA_ARGS__, T_END0); } \ else if ( !strcmp("ID",key) ) { function(__VA_ARGS__, T_ID); } \ else if ( !strcmp("REF",key) ) { function(__VA_ARGS__, T_REF); } \ else if ( !strcmp("FIRST_ALT",key) ) { function(__VA_ARGS__, T_FIRST_ALT); } \ else if ( !strcmp("QUAL",key) ) { function(__VA_ARGS__, T_QUAL); } \ else if ( !strcmp("TYPE",key) ) { function(__VA_ARGS__, T_TYPE); } \ else if ( !strcmp("FILTER",key) ) { function(__VA_ARGS__, T_FILTER); } \ else if ( !strcmp("IS_TS",key) ) { function(__VA_ARGS__, T_IS_TS); } \ else if ( !strcmp("MASK",key) ) { function(__VA_ARGS__, T_MASK); } \ else if ( !strcmp("LINE",key) ) { function(__VA_ARGS__, T_LINE); } static void set_type(fmt_t *fmt, int type) { fmt->type = type; } static fmt_t *register_tag(convert_t *convert, char *key, int is_gtf, int type) { convert->nfmt++; if ( convert->nfmt > convert->mfmt ) { convert->mfmt += 10; convert->fmt = (fmt_t*) realloc(convert->fmt, convert->mfmt*sizeof(fmt_t)); } fmt_t *fmt = &convert->fmt[ convert->nfmt-1 ]; fmt->type = type; fmt->key = key ? strdup(key) : NULL; fmt->is_gt_field = is_gtf; fmt->subscript = -1; fmt->usr = NULL; fmt->destroy = NULL; // Allow non-format tags, such as CHROM, INFO, etc., to appear amongst the format tags. if ( key ) { int id = bcf_hdr_id2int(convert->header, BCF_DT_ID, key); if ( fmt->type==T_FORMAT && !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,id) ) { _SET_NON_FORMAT_TAGS(set_type,key,fmt) else if ( !strcmp("ALT",key) ) { fmt->type = T_ALT; } else if ( !strcmp("_CHROM_POS_ID",key) ) { fmt->type = T_CHROM_POS_ID; } else if ( !strcmp("RSX",key) ) { fmt->type = T_RSX; } else if ( !strcmp("VKX",key) ) { fmt->type = T_VKX; } else if ( id>=0 && bcf_hdr_idinfo_exists(convert->header,BCF_HL_INFO,id) ) { fmt->type = T_INFO; _used_tags_add(convert,T_INFO,key); } } else if ( fmt->type==T_PBINOM ) { fmt->id = bcf_hdr_id2int(convert->header, BCF_DT_ID, fmt->key); if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT, fmt->id) ) error("No such FORMAT tag defined in the header: %s\n", fmt->key); _used_tags_add(convert,T_FORMAT,key); } else if ( fmt->type==T_NPASS ) { filter_t *flt = filter_init(convert->header,key); convert->max_unpack |= filter_max_unpack(flt); fmt->usr = (void*) flt; } } switch (fmt->type) { case T_FIRST_ALT: fmt->handler = &process_first_alt; break; case T_CHROM_POS_ID: fmt->handler = &process_chrom_pos_id; break; case T_GT_TO_PROB3: fmt->handler = &process_gt_to_prob3; break; case T_PL_TO_PROB3: fmt->handler = &process_pl_to_prob3; break; case T_GP_TO_PROB3: fmt->handler = &process_gp_to_prob3; break; case T_CHROM: fmt->handler = &process_chrom; break; case T_POS: fmt->handler = &process_pos; break; case T_POS0: fmt->handler = &process_pos0; break; case T_END: fmt->handler = &process_end; convert->max_unpack |= BCF_UN_INFO; break; case T_END0: fmt->handler = &process_end0; convert->max_unpack |= BCF_UN_INFO; break; case T_ID: fmt->handler = &process_id; break; case T_REF: fmt->handler = &process_ref; break; case T_ALT: fmt->handler = &process_alt; break; case T_QUAL: fmt->handler = &process_qual; break; case T_FILTER: fmt->handler = &process_filter; convert->max_unpack |= BCF_UN_FLT; break; case T_INFO: fmt->handler = &process_info; convert->max_unpack |= BCF_UN_INFO; break; case T_FORMAT: fmt->handler = fmt->key ? &process_format : &process_complete_format; convert->max_unpack |= BCF_UN_FMT; break; case T_SAMPLE: fmt->handler = &process_sample; break; case T_SEP: fmt->handler = &process_sep; break; case T_IS_TS: fmt->handler = &process_is_ts; break; case T_TYPE: fmt->handler = &process_type; break; case T_MASK: fmt->handler = NULL; break; case T_GT: fmt->handler = &process_gt; convert->max_unpack |= BCF_UN_FMT; break; case T_TGT: fmt->handler = &process_tgt; convert->max_unpack |= BCF_UN_FMT; break; case T_IUPAC_GT: fmt->handler = &process_iupac_gt; convert->max_unpack |= BCF_UN_FMT; break; case T_GT_TO_HAP: fmt->handler = &process_gt_to_hap; convert->max_unpack |= BCF_UN_FMT; break; case T_GT_TO_HAP2: fmt->handler = &process_gt_to_hap2; convert->max_unpack |= BCF_UN_FMT; break; case T_TBCSQ: fmt->handler = &process_tbcsq; fmt->destroy = &destroy_tbcsq; convert->max_unpack |= BCF_UN_FMT; break; case T_LINE: fmt->handler = &process_line; convert->max_unpack |= BCF_UN_FMT; break; case T_RSX: fmt->handler = &process_rsid_hex; break; case T_VKX: fmt->handler = &process_variantkey_hex; break; case T_PBINOM: fmt->handler = &process_pbinom; convert->max_unpack |= BCF_UN_FMT; break; case T_NPASS: fmt->handler = &process_npass; fmt->destroy = &destroy_npass; break; default: error("TODO: handler for type %d\n", fmt->type); } if ( key && fmt->type==T_INFO ) { fmt->id = bcf_hdr_id2int(convert->header, BCF_DT_ID, key); if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_INFO,fmt->id) ) { fmt->id = -1; convert->undef_info_tag = strdup(key); } } return fmt; } static int parse_subscript(char **p) { char *q = *p; if ( *q!='{' ) return -1; q++; while ( *q && *q!='}' && isdigit(*q) ) q++; if ( *q!='}' ) return -1; int idx = atoi((*p)+1); *p = q+1; return idx; } static char *parse_tag(convert_t *convert, char *p, int is_gtf) { char *q = ++p; while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; kstring_t str = {0,0,0}; if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); kputsn(p, q-p, &str); if ( is_gtf ) { if ( !strcmp(str.s, "SAMPLE") ) register_tag(convert, "SAMPLE", is_gtf, T_SAMPLE); else if ( !strcmp(str.s, "GT") ) register_tag(convert, "GT", is_gtf, T_GT); else if ( !strcmp(str.s, "TGT") ) register_tag(convert, "GT", is_gtf, T_TGT); else if ( !strcmp(str.s, "TBCSQ") ) { fmt_t *fmt = register_tag(convert, "BCSQ", is_gtf, T_TBCSQ); fmt->subscript = parse_subscript(&q); if ( fmt->subscript==-1 ) { if ( !strncmp(q,"{*}",3) ) { fmt->subscript = 0; q += 3; } } else fmt->subscript++; } else if ( !strcmp(str.s, "IUPACGT") ) register_tag(convert, "GT", is_gtf, T_IUPAC_GT); else if ( !strcmp(str.s, "INFO") ) { if ( *q!='/' ) { int id = bcf_hdr_id2int(convert->header, BCF_DT_ID, str.s); if ( bcf_hdr_idinfo_exists(convert->header,BCF_HL_INFO,id) ) error("Could not parse format string \"%s\". Did you mean %%INFO/%s?\n", convert->format_str,str.s); else error("Could not parse format string: %s\n", convert->format_str); } p = ++q; str.l = 0; while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); kputsn(p, q-p, &str); fmt_t *fmt = register_tag(convert, str.s, is_gtf, T_INFO); fmt->subscript = parse_subscript(&q); _used_tags_add(convert,T_INFO,str.s); } else if ( !strcmp(str.s,"PBINOM") ) { if ( *q!='(' ) error("Could not parse the expression: %s\n", convert->format_str); p = ++q; str.l = 0; while ( *q && *q!=')' ) q++; if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); kputsn(p, q-p, &str); register_tag(convert, str.s, is_gtf, T_PBINOM); q++; } else if ( !strcmp(str.s,"N_PASS") ) error("N_PASS() must be placed outside the square brackets\n"); else { fmt_t *fmt = register_tag(convert, str.s, is_gtf, T_FORMAT); fmt->subscript = parse_subscript(&q); } } else { _SET_NON_FORMAT_TAGS(register_tag, str.s, convert, str.s, is_gtf) else if ( !strcmp(str.s, "ALT") ) { fmt_t *fmt = register_tag(convert, str.s, is_gtf, T_ALT); fmt->subscript = parse_subscript(&q); } else if ( !strcmp(str.s, "_CHROM_POS_ID") ) register_tag(convert, str.s, is_gtf, T_CHROM_POS_ID); else if ( !strcmp(str.s, "_GT_TO_PROB3") ) register_tag(convert, str.s, is_gtf, T_GT_TO_PROB3); else if ( !strcmp(str.s, "_PL_TO_PROB3") ) register_tag(convert, str.s, is_gtf, T_PL_TO_PROB3); else if ( !strcmp(str.s, "_GP_TO_PROB3") ) register_tag(convert, str.s, is_gtf, T_GP_TO_PROB3); else if ( !strcmp(str.s, "_GT_TO_HAP") ) register_tag(convert, str.s, is_gtf, T_GT_TO_HAP); else if ( !strcmp(str.s, "_GT_TO_HAP2") ) register_tag(convert, str.s, is_gtf, T_GT_TO_HAP2); else if ( !strcmp(str.s, "RSX") ) register_tag(convert, str.s, is_gtf, T_RSX); else if ( !strcmp(str.s, "VKX") ) register_tag(convert, str.s, is_gtf, T_VKX); else if ( !strcmp(str.s,"PBINOM") ) error("Error: PBINOM() is currently supported only with FORMAT tags. (todo)\n"); else if ( !strcmp(str.s, "INFO") ) { if ( *q=='/' ) { p = ++q; str.l = 0; while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); kputsn(p, q-p, &str); fmt_t *fmt = register_tag(convert, str.s, is_gtf, T_INFO); fmt->subscript = parse_subscript(&q); _used_tags_add(convert,T_INFO,str.s); } else register_tag(convert, NULL, is_gtf, T_INFO); // the whole INFO } else if ( !strcmp(str.s, "FORMAT") ) register_tag(convert, NULL, 0, T_FORMAT); else if ( !strcmp(str.s,"N_PASS") ) { if ( *q!='(' ) error("Could not parse the expression: %s\n", convert->format_str); p = ++q; str.l = 0; int nopen = 1; while ( *q && nopen ) { if ( *q=='(' ) nopen++; else if ( *q==')' ) nopen--; q++; } if ( q-p==0 || nopen ) error("Could not parse format string: %s\n", convert->format_str); kputsn(p, q-p-1, &str); register_tag(convert, str.s, is_gtf, T_NPASS); } else { fmt_t *fmt = register_tag(convert, str.s, is_gtf, T_INFO); fmt->subscript = parse_subscript(&q); _used_tags_add(convert,T_INFO,str.s); } } free(str.s); return q; } static char *parse_sep(convert_t *convert, char *p, int is_gtf) { char *q = p; kstring_t str = {0,0,0}; while ( *q && *q!='[' && *q!=']' && *q!='%' ) { if ( *q=='\\' ) { q++; if ( *q=='n' ) kputc('\n', &str); else if ( *q=='t' ) kputc('\t', &str); else kputc(*q, &str); } else kputc(*q, &str); q++; } if ( !str.l ) error("Could not parse format string: %s\n", convert->format_str); register_tag(convert, str.s, is_gtf, T_SEP); free(str.s); return q; } convert_t *convert_init(bcf_hdr_t *hdr, int *samples, int nsamples, const char *format_str) { convert_t *convert = (convert_t*) calloc(1,sizeof(convert_t)); convert->header = hdr; convert->format_str = strdup(format_str); convert->max_unpack = BCF_UN_STR; convert->used_tags_hash = khash_str2int_init(); int i, is_gtf = 0; char *p = convert->format_str; while ( *p ) { //fprintf(stderr,"<%s>\n", p); switch (*p) { case '[': is_gtf = 1; p++; break; case ']': is_gtf = 0; register_tag(convert, NULL, 0, T_SEP); p++; break; case '%': p = parse_tag(convert, p, is_gtf); break; default: p = parse_sep(convert, p, is_gtf); break; } } if ( is_gtf ) error("Could not parse the format string, missing the square bracket \"]\": %s\n", convert->format_str); if ( nsamples ) { convert->nsamples = nsamples; convert->samples = (int*) malloc(sizeof(int)*nsamples); for (i=0; insamples; i++) convert->samples[i] = samples[i]; } else { convert->nsamples = bcf_hdr_nsamples(convert->header); convert->samples = (int*) malloc(sizeof(int)*convert->nsamples); for (i=0; insamples; i++) convert->samples[i] = i; } return convert; } void convert_destroy(convert_t *convert) { int i; for (i=0; infmt; i++) { if ( convert->fmt[i].destroy ) convert->fmt[i].destroy(convert->fmt[i].usr); free(convert->fmt[i].key); } if ( convert->nused_tags ) { for (i=0; inused_tags; i++) free(convert->used_tags_list[i]); free(convert->used_tags_list); } khash_str2int_destroy(convert->used_tags_hash); free(convert->print_filtered); free(convert->fmt); free(convert->undef_info_tag); free(convert->dat); free(convert->samples); free(convert->format_str); free(convert); } int convert_header(convert_t *convert, kstring_t *str) { int i, icol = 0, l_ori = str->l; bcf_hdr_t *hdr = convert->header; // Suppress the header output if LINE is present for (i=0; infmt; i++) if ( convert->fmt[i].type == T_LINE ) break; if ( i!=convert->nfmt ) return str->l - l_ori; // Header formatting becomes problematic when the formatting expression contains a newline. // Simple cases like // -f'[%CHROM %POS %SAMPLE\n]' // can be handled quite easily with has_fmt_newline. Note this will not work if multiple newlines // are present. int has_fmt_newline = 0; kputc('#', str); for (i=0; infmt; i++) { // Genotype fields if ( convert->fmt[i].is_gt_field ) { int j = i, js, k; while ( convert->fmt[j].is_gt_field ) j++; for (js=0; jsnsamples; js++) { int ks = convert->samples[js]; for (k=i; kfmt[k].type == T_SEP ) { if ( convert->fmt[k].key ) { char *tmp = convert->fmt[k].key; while ( *tmp ) { if ( *tmp=='\n' ) has_fmt_newline = 1; else kputc(*tmp,str); tmp++; } } } else if ( convert->header_samples ) { icol++; if ( !convert->no_hdr_indices ) ksprintf(str,"[%d]",icol); ksprintf(str,"%s:%s", hdr->samples[ks], convert->fmt[k].key); } else { icol++; if ( !convert->no_hdr_indices ) ksprintf(str,"[%d]",icol); ksprintf(str,"%s", convert->fmt[k].key); } } if ( has_fmt_newline ) { if ( !convert->header_samples ) break; // this is unfortunate: the formatting expression breaks the per-sample output into separate lines, // therefore including a sample name in the header makes no sense anymore convert->header_samples = 0; str->l = l_ori; return convert_header(convert, str); } } i = j-1; continue; } // Fixed fields if ( convert->fmt[i].type == T_SEP ) { if ( convert->fmt[i].key ) kputs(convert->fmt[i].key, str); continue; } icol++; if ( !convert->no_hdr_indices ) ksprintf(str,"[%d]",icol); ksprintf(str,"%s", convert->fmt[i].key); } if ( has_fmt_newline ) kputc('\n',str); return str->l - l_ori; } int convert_line(convert_t *convert, bcf1_t *line, kstring_t *str) { if ( !convert->allow_undef_tags && convert->undef_info_tag ) { kstring_t msg = {0,0,0}; ksprintf(&msg,"Error: no such tag defined in the VCF header: INFO/%s", convert->undef_info_tag); int hdr_id = bcf_hdr_id2int(convert->header,BCF_DT_ID,convert->undef_info_tag); if ( hdr_id>=0 && bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,hdr_id) ) ksprintf(&msg,". FORMAT fields must be enclosed in square brackets, e.g. \"[ %%%s]\"", convert->undef_info_tag); error("%s\n", msg.s); } int l_ori = str->l; bcf_unpack(line, convert->max_unpack); int i, ir; str->l = 0; for (i=0; infmt; i++) { // Genotype fields. if ( convert->fmt[i].is_gt_field ) { int j = i, js, k; while ( jnfmt && convert->fmt[j].is_gt_field ) { convert->fmt[j].ready = 0; j++; } for (js=0; jsnsamples; js++) { // Skip samples when filtering was requested int ks = convert->samples[js]; if ( convert->subset_samples && *convert->subset_samples && !(*convert->subset_samples)[ks] ) { if ( !convert->print_filtered ) continue; for (k=i; kfmt[k].type==T_SEP ) convert->fmt[k].handler(convert, line, &convert->fmt[k], ks, str); else kputs(convert->print_filtered, str); continue; } // Here comes a hack designed for TBCSQ. When running on large files, // such as 1000GP, there are too many empty fields in the output and // it's very very slow. Therefore in case the handler does not add // anything to the string, we trim all genotype fields enclosed in square // brackets here. This may be changed in future, time will show... size_t l_start = str->l; for (k=i; kfmt[k].type == T_MASK ) { for (ir=0; irnreaders; ir++) kputc(bcf_sr_has_line(convert->readers,ir)?'1':'0', str); } else if ( convert->fmt[k].handler ) { size_t l = str->l; convert->fmt[k].handler(convert, line, &convert->fmt[k], ks, str); if ( l==str->l ) { str->l = l_start; break; } // only TBCSQ does this } } } i = j-1; continue; } // Fixed fields if ( convert->fmt[i].type == T_MASK ) { for (ir=0; irnreaders; ir++) kputc(bcf_sr_has_line(convert->readers,ir)?'1':'0', str); } else if ( convert->fmt[i].handler ) convert->fmt[i].handler(convert, line, &convert->fmt[i], -1, str); } return str->l - l_ori; } static void force_newline_(convert_t *convert) { int i, has_newline = 0; for (i=0; infmt; i++) { if ( !convert->fmt[i].key ) continue; char *tmp = convert->fmt[i].key; while (*tmp) { if ( *tmp=='\n' ) { has_newline = 1; break; } tmp++; } if ( has_newline ) break; } if ( has_newline ) return; // A newline is not present, force it. But where to add it? Always at the end. // // Briefly, in 1.18, we considered the following automatic behavior, which for // per-site output it would add it at the end of the expression and for per-sample // output it would add it inside the square brackets: // -f'%CHROM[ %SAMPLE]\n' // -f'[%CHROM %SAMPLE\n]' // // However, this is an annoyance for users, as it is not entirely clear what // will happen unless one understands the internals well (#1969) register_tag(convert, "\n", 0, T_SEP); } int convert_set_option(convert_t *convert, enum convert_option opt, ...) { int ret = 0; va_list args; va_start(args, opt); switch (opt) { case allow_undef_tags: convert->allow_undef_tags = va_arg(args, int); break; case subset_samples: convert->subset_samples = va_arg(args, uint8_t**); break; case header_samples: convert->header_samples = va_arg(args, int); break; case print_filtered: convert->print_filtered = strdup(va_arg(args, char*)); break; case force_newline: convert->force_newline = va_arg(args, int); if ( convert->force_newline ) force_newline_(convert); break; case no_hdr_indices: convert->no_hdr_indices = va_arg(args, int); break; default: ret = -1; } va_end(args); return ret; } int convert_max_unpack(convert_t *convert) { return convert->max_unpack; } int convert_is_tag_used(convert_t *convert, char *tag) { return khash_str2int_has_key(convert->used_tags_hash, tag); } const char **convert_list_used_tags(convert_t *convert, int *ntags) { *ntags = convert->nused_tags; return (const char **)convert->used_tags_list; } bcftools-1.21/convert.h000066400000000000000000000046761467060157400151300ustar00rootroot00000000000000/* convert.h -- functions for converting between VCF/BCF and related formats. Copyright (C) 2014-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __CONVERT_H__ #define __CONVERT_H__ #include typedef struct _convert_t convert_t; enum convert_option { allow_undef_tags, // see `bcftools query --allow-undef-tags`, throws an error if tag is not defined otherwise subset_samples, // in bracketed expressions (e.g. [ %GT]) consider only marked samples header_samples, // include sample name in bracketed tags (e.g. SAMPLE1:GT SAMPLE2:GT for [ %GT]) force_newline, // automatically insert a newline when not part of the formatting expression print_filtered, // print the provided string instead of discarding samples not included in subset_samples no_hdr_indices, // drop column indices when printing header, i.e. "#CHROM", not "#[1]CHROM" }; convert_t *convert_init(bcf_hdr_t *hdr, int *samples, int nsamples, const char *str); void convert_destroy(convert_t *convert); int convert_set_option(convert_t *convert, enum convert_option opt, ...); int convert_header(convert_t *convert, kstring_t *str); int convert_line(convert_t *convert, bcf1_t *rec, kstring_t *str); int convert_max_unpack(convert_t *convert); int convert_is_tag_used(convert_t *convert, char *tag); const char **convert_list_used_tags(convert_t *convert, int *ntags); #endif bcftools-1.21/csq.c000066400000000000000000004346321467060157400142300ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Things that would be nice to have - dynamic N_REF_PAD - for stop-lost events (also in frameshifts) report the number of truncated aa's - memory could be greatly reduced by indexing gff (but it is quite compact already) - deletions that go beyond transcript boundaries are not checked at sequence level - alloc tscript->ref in hap_finalize, introduce fa_off_beg:16,fa_off_end:16 - see test/csq/ENST00000573314/insertion-overlap.vcf #1476288882 Read about transcript types here http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html https://www.ensembl.org/info/genome/variation/prediction/predicted_data.html https://www.gencodegenes.org/pages/biotypes.html List of supported biotypes antisense IG_C_gene IG_D_gene IG_J_gene IG_LV_gene IG_V_gene lincRNA lncRNA .. generic term for 3prime_overlapping_ncRNA, antisense, bidirectional_promoter_lncRNA, lincRNA, macro_lncRNA, non_coding, processed_transcript, sense_intronic, sense_overlapping macro_lncRNA miRNA misc_RNA Mt_rRNA Mt_tRNA polymorphic_pseudogene processed_transcript protein_coding, mRNA ribozyme rRNA sRNA scRNA scaRNA sense_intronic sense_overlapping snRNA snoRNA TR_C_gene TR_D_gene TR_J_gene TR_V_gene The gff parsing logic We collect features such by combining gff lines A,B,C as follows: A .. gene line with a supported biotype A.ID=~/^gene:/ B .. transcript line referencing A with supported biotype B.ID=~/^transcript:/ && B.Parent=~/^gene:A.ID/ C .. corresponding CDS, exon, and UTR lines: C[3] in {"CDS","exon","three_prime_UTR","five_prime_UTR"} && C.Parent=~/^transcript:B.ID/ For coding biotypes ("protein_coding" or "polymorphic_pseudogene") the complete chain link C -> B -> A is required. For the rest, link B -> A suffices. The supported consequence types, sorted by impact: splice_acceptor_variant .. end region of an intron changed (2bp at the 3' end of an intron) splice_donor_variant .. start region of an intron changed (2bp at the 5' end of an intron) stop_gained .. DNA sequence variant resulting in a stop codon frameshift_variant .. number of inserted/deleted bases not a multiple of three, disrupted translational frame stop_lost .. elongated transcript, stop codon changed start_lost .. the first codon changed inframe_altering .. combination of indels leading to unchanged reading frame and length inframe_insertion .. inserted coding sequence, unchanged reading frame inframe_deletion .. deleted coding sequence, unchanged reading frame missense_variant .. amino acid (aa) change, unchanged length splice_region_variant .. change within 1-3 bases of the exon or 3-8 bases of the intron synonymous_variant .. DNA sequence variant resulting in no amino acid change stop_retained_variant .. different stop codon start_retained_variant .. start codon retained by indel realignment non_coding_variant .. variant in non-coding sequence, such as RNA gene 5_prime_UTR_variant 3_prime_UTR_variant intron_variant .. reported only if none of the above intergenic_variant .. reported only if none of the above The annotation algorithm. The algorithm checks if the variant falls in a region of a supported type. The search is performed in the following order, until a match is found: 1. idx_cds(gf_cds_t) - lookup CDS by position, create haplotypes, call consequences 2. idx_utr(gf_utr_t) - check UTR hits 3. idx_exon(gf_exon_t) - check for splice variants 4. idx_tscript(tscript_t) - check for intronic variants, RNAs, etc. These regidx indexes are created by parsing a gff3 file as follows: 1. create the array "ftr" of all UTR, CDS, exons. This will be processed later and pruned based on transcript types we want to keep. In the same go, create the hash "id2tr" of transcripts to keep (based on biotype) which maps from transcript_id to a transcript. At the same time also build the hash "gid2gene" which maps from gene_id to gf_gene_t pointer. 2. build "idx_cds", "idx_tscript", "idx_utr" and "idx_exon" indexes. Use only features from "ftr" which are present in "id2tr". 3. clean data that won't be needed anymore: ftr, id2tr, gid2gene. Data structures. idx_cds, idx_utr, idx_exon, idx_tscript: as described above, regidx structures for fast lookup of exons/transcripts overlapping a region, the payload is a pointer to tscript.cds */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "regidx.h" #include "kheap.h" #include "smpl_ilist.h" #include "rbuf.h" #include "gff.h" #ifndef __FUNCTION__ # define __FUNCTION__ __func__ #endif // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define N_REF_PAD 10 // number of bases to avoid boundary effects // How to treat phased/unphased genotypes #define PHASE_REQUIRE 0 // --phase r #define PHASE_MERGE 1 // --phase m #define PHASE_AS_IS 2 // --phase a #define PHASE_SKIP 3 // --phase s #define PHASE_NON_REF 4 // --phase R #define PHASE_DROP_GT 5 // --samples - // Node types in the haplotype tree #define HAP_CDS 0 #define HAP_ROOT 1 #define HAP_SSS 2 // start/stop/splice #define CSQ_PRINTED_UPSTREAM (1<<0) #define CSQ_SYNONYMOUS_VARIANT (1<<1) #define CSQ_MISSENSE_VARIANT (1<<2) #define CSQ_STOP_LOST (1<<3) #define CSQ_STOP_GAINED (1<<4) #define CSQ_INFRAME_DELETION (1<<5) #define CSQ_INFRAME_INSERTION (1<<6) #define CSQ_FRAMESHIFT_VARIANT (1<<7) #define CSQ_SPLICE_ACCEPTOR (1<<8) #define CSQ_SPLICE_DONOR (1<<9) #define CSQ_START_LOST (1<<10) #define CSQ_SPLICE_REGION (1<<11) #define CSQ_STOP_RETAINED (1<<12) #define CSQ_UTR5 (1<<13) #define CSQ_UTR3 (1<<14) #define CSQ_NON_CODING (1<<15) #define CSQ_INTRON (1<<16) //#define CSQ_INTERGENIC (1<<17) #define CSQ_INFRAME_ALTERING (1<<18) #define CSQ_UPSTREAM_STOP (1<<19) // adds * in front of the csq string #define CSQ_INCOMPLETE_CDS (1<<20) // to remove START/STOP in incomplete CDS, see ENSG00000173376/synon.vcf #define CSQ_CODING_SEQUENCE (1<<21) // cannot tell exactly what it is, but it does affect the coding sequence #define CSQ_ELONGATION (1<<22) // symbolic insertion #define CSQ_START_RETAINED (1<<23) // Haplotype-aware consequences, printed in one vcf record only, the rest has a reference @12345 #define CSQ_COMPOUND (CSQ_SYNONYMOUS_VARIANT|CSQ_MISSENSE_VARIANT|CSQ_STOP_LOST|CSQ_STOP_GAINED| \ CSQ_INFRAME_DELETION|CSQ_INFRAME_INSERTION|CSQ_FRAMESHIFT_VARIANT| \ CSQ_START_LOST|CSQ_STOP_RETAINED|CSQ_INFRAME_ALTERING|CSQ_INCOMPLETE_CDS| \ CSQ_UPSTREAM_STOP|CSQ_START_RETAINED) #define CSQ_START_STOP (CSQ_STOP_LOST|CSQ_STOP_GAINED|CSQ_STOP_RETAINED|CSQ_START_LOST|CSQ_START_RETAINED) #define CSQ_PRN_STRAND(csq) ((csq)&CSQ_COMPOUND && !((csq)&(CSQ_SPLICE_ACCEPTOR|CSQ_SPLICE_DONOR|CSQ_SPLICE_REGION))) #define CSQ_PRN_TSCRIPT (~(CSQ_INTRON|CSQ_NON_CODING)) #define CSQ_PRN_NMD (~(CSQ_INTRON|CSQ_NON_CODING)) #define CSQ_PRN_BIOTYPE CSQ_NON_CODING // see kput_vcsq() const char *csq_strings[] = { NULL, "synonymous", "missense", "stop_lost", "stop_gained", "inframe_deletion", "inframe_insertion", "frameshift", "splice_acceptor", "splice_donor", "start_lost", "splice_region", "stop_retained", "5_prime_utr", "3_prime_utr", "non_coding", "intron", "intergenic", "inframe_altering", NULL, NULL, "coding_sequence", "feature_elongation", "start_retained" }; /* Structures related to VCF output: vcsq_t information required to assemble consequence lines such as "inframe_deletion|XYZ|ENST01|+|5TY>5I|121ACG>A+124TA>T" vrec_t single VCF record and csq tied to this record. (Haplotype can have multiple consequences in several VCF records. Each record can have multiple consequences from multiple haplotypes.) csq_t a top-level consequence tied to a haplotype vbuf_t pos2vbuf VCF records with the same position clustered together for a fast lookup via pos2vbuf */ typedef struct _vbuf_t vbuf_t; typedef struct _vcsq_t vcsq_t; struct _vcsq_t { uint32_t strand:1, type:31; // one of CSQ_* types uint32_t trid; uint32_t vcf_ial; uint32_t biotype; // one of GF_* types char *gene; // gene name bcf1_t *ref; // if type&CSQ_PRINTED_UPSTREAM, ref consequence "@1234" kstring_t vstr; // variant string, eg 5TY>5I|121ACG>A+124TA>T }; typedef struct { bcf1_t *line; uint32_t *fmt_bm; // bitmask of sample consequences with first/second haplotype interleaved uint32_t nfmt:4, // the bitmask size (the number of integers per sample) nvcsq:28, mvcsq; vcsq_t *vcsq; // there can be multiple consequences for a single VCF record } vrec_t; typedef struct { uint32_t pos; vrec_t *vrec; // vcf line that this csq is tied to; needed when printing haplotypes (hap_stage_vcf) int idx; // 0-based index of the csq at the VCF line, for FMT/BCSQ vcsq_t type; } csq_t; struct _vbuf_t { vrec_t **vrec; // buffer of VCF lines with the same position int n, m; uint32_t keep_until; // the maximum transcript end position }; KHASH_MAP_INIT_INT(pos2vbuf, vbuf_t*) /* Structures related to haplotype-aware consequences in coding regions hap_node_t node of a haplotype tree. Each transcript has one tree tscript_t despite its general name, it is intended for coding transcripts only hap_t hstack_t for traversal of the haplotype tree and braking combined consequences into independent parts */ typedef struct _hap_node_t hap_node_t; struct _hap_node_t { char *seq; // cds segment [parent_node,this_node) char *var; // variant "ref>alt" uint32_t type:2, // HAP_ROOT or HAP_CDS csq:30; // this node's consequence int dlen; // alt minus ref length: <0 del, >0 ins, 0 substitution uint32_t rbeg; // variant's VCF position (0-based, inclusive) int32_t rlen; // variant's rlen; alen=rlen+dlen; fake for non CDS types uint32_t sbeg; // variant's position on the spliced reference transcript (0-based, inclusive, N_REF_PAD not included) uint32_t icds; // which exon does this node's variant overlaps hap_node_t **child, *prev; // children haplotypes and previous coding node int nchild, mchild; bcf1_t *cur_rec, *rec; // current VCF record and node's VCF record int vcf_ial; // which VCF allele generated this node uint32_t nend; // number of haplotypes ending in this node int *cur_child, mcur_child; // mapping from the allele to the currently active child csq_t *csq_list; // list of haplotype's consequences, broken by position (each corresponds to a VCF record) int ncsq_list, mcsq_list; }; #define TSCRIPT_AUX(x) ((tscript_t*)(x)->aux) typedef struct { char *ref; // reference sequence, padded with N_REF_PAD bases on both ends char *sref; // spliced reference sequence, padded with N_REF_PAD bases on both ends hap_node_t *root; // root of the haplotype tree hap_node_t **hap; // pointer to haplotype leaves, two for each sample int nhap, nsref; // number of haplotypes and length of sref, including 2*N_REF_PAD } tscript_t; static inline int cmp_tscript(gf_tscript_t **a, gf_tscript_t **b) { return ( (*a)->end < (*b)->end ) ? 1 : 0; } KHEAP_INIT(trhp, gf_tscript_t*, cmp_tscript) typedef khp_trhp_t tr_heap_t; typedef struct { hap_node_t *node; // current node int ichild; // current child in the active node int dlen; // total dlen, from the root to the active node size_t slen; // total sequence length, from the root to the active node } hstack_t; typedef struct { int mstack; hstack_t *stack; gf_tscript_t *tr; // tr->ref: spliced transcript on ref strand kstring_t sseq; // spliced haplotype sequence on ref strand kstring_t tseq; // the variable part of translated haplotype transcript, coding strand kstring_t tref; // the variable part of translated reference transcript, coding strand uint32_t sbeg; // stack's sbeg, for cases first node's type is HAP_SSS int upstream_stop; } hap_t; typedef struct _args_t { // the main regidx lookups, from chr:beg-end to overlapping features and // index iterator gff_t *gff; regidx_t *idx_cds, *idx_utr, *idx_exon, *idx_tscript; regitr_t *itr; // text tab-delimited output (out) or vcf/bcf output (out_fh) FILE *out; htsFile *out_fh; char *index_fn; int write_index; char *dump_gff; // vcf bcf_srs_t *sr; bcf_hdr_t *hdr; int hdr_nsmpl; // actual number of samples in the vcf, for bcf_update_format_values() // include or exclude sites which match the filters filter_t *filter; char *filter_str; int filter_logic; // FLT_INCLUDE or FLT_EXCLUDE // samples to process int sample_is_file; char *sample_list; smpl_ilist_t *smpl; char *outdir, **argv, *fa_fname, *gff_fname, *output_fname; char *bcsq_tag; int argc, output_type, clevel; int phase, verbosity, local_csq, record_cmd_line; int ncsq2_max, nfmt_bcsq; // maximum number of csq per site that can be accessed from FORMAT/BCSQ (*2 and 1 bit skipped to avoid BCF missing values) int ncsq2_small_warned; int brief_predictions; int unify_chr_names; char *chr_name; int mchr_name; struct { int unknown_chr,unknown_tscript_biotype,unknown_strand,unknown_phase,duplicate_id; int unknown_cds_phase,incomplete_cds,wrong_phase,overlapping_cds; } warned; int rid; // current chromosome tr_heap_t *active_tr; // heap of active transcripts for quick flushing hap_t *hap; // transcript haplotype recursion vbuf_t **vcf_buf; // buffered VCF lines to annotate with CSQ and flush rbuf_t vcf_rbuf; // round buffer indexes to vcf_buf kh_pos2vbuf_t *pos2vbuf; // fast lookup of buffered lines by position gf_tscript_t **rm_tr; // buffer of transcripts to clean int nrm_tr, mrm_tr; csq_t *csq_buf; // pool of csq not managed by hap_node_t, i.e. non-CDS csqs int ncsq_buf, mcsq_buf; int force; // force run under various conditions. Currently only to skip out-of-phase transcripts int n_threads; // extra compression/decompression threads faidx_t *fai; kstring_t str, str2; int32_t *gt_arr, mgt_arr; } args_t; // AAA, AAC, ... const char *gencode = "KNKNTTTTRSRSIIMIQHQHPPPPRRRRLLLLEDEDAAAAGGGGVVVV*Y*YSSSS*CWCLFLF"; const uint8_t nt4[] = { 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,0,4,1, 4,4,4,2, 4,4,4,4, 4,4,4,4, 4,4,4,4, 3,4,4,4, 4,4,4,4, 4,4,4,4, 4,0,4,1, 4,4,4,2, 4,4,4,4, 4,4,4,4, 4,4,4,4, 3 }; const uint8_t cnt4[] = { 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,3,4,2, 4,4,4,1, 4,4,4,4, 4,4,4,4, 4,4,4,4, 0,4,4,4, 4,4,4,4, 4,4,4,4, 4,3,4,2, 4,4,4,1, 4,4,4,4, 4,4,4,4, 4,4,4,4, 0 }; #define dna2aa(x) gencode[ nt4[(uint8_t)(x)[0]]<<4 | nt4[(uint8_t)(x)[1]]<<2 | nt4[(uint8_t)(x)[2]] ] #define cdna2aa(x) gencode[ cnt4[(uint8_t)(x)[2]]<<4 | cnt4[(uint8_t)(x)[1]]<<2 | cnt4[(uint8_t)(x)[0]] ] static inline int ncsq2_to_nfmt(int ncsq2) { return 1 + (ncsq2 - 1) / 30; } static inline void icsq2_to_bit(int icsq2, int *ival, int *ibit) { *ival = icsq2 / 30; *ibit = icsq2 % 30; } void init_data(args_t *args) { args->nfmt_bcsq = ncsq2_to_nfmt(args->ncsq2_max); args->fai = fai_load(args->fa_fname); if ( !args->fai ) error("Failed to load the fai index: %s\n", args->fa_fname); args->gff = gff_init(args->gff_fname); gff_set(args->gff,verbosity,args->verbosity); gff_set(args->gff,strip_chr_names,args->unify_chr_names); gff_set(args->gff,force_out_of_phase,args->force); gff_set(args->gff,dump_fname,args->dump_gff); gff_parse(args->gff); args->idx_cds = gff_get(args->gff,idx_cds); args->idx_utr = gff_get(args->gff,idx_utr); args->idx_exon = gff_get(args->gff,idx_exon); args->idx_tscript = gff_get(args->gff,idx_tscript); args->itr = regitr_init(NULL); args->rid = -1; if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); args->pos2vbuf = kh_init(pos2vbuf); args->active_tr = khp_init(trhp); args->hap = (hap_t*) calloc(1,sizeof(hap_t)); // init samples if ( !bcf_hdr_nsamples(args->hdr) ) args->phase = PHASE_DROP_GT; if ( args->sample_list && !strcmp("-",args->sample_list) ) { // ignore all samples if ( args->output_type==FT_TAB_TEXT ) { // significant speedup for plain VCFs if (bcf_hdr_set_samples(args->hdr,NULL,0) < 0) error_errno("[%s] Couldn't build sample filter", __func__); } args->phase = PHASE_DROP_GT; } else args->smpl = smpl_ilist_init(args->hdr, args->sample_list, args->sample_is_file, SMPL_STRICT); args->hdr_nsmpl = args->phase==PHASE_DROP_GT ? 0 : bcf_hdr_nsamples(args->hdr); if ( args->output_type==FT_TAB_TEXT ) { args->out = args->output_fname ? fopen(args->output_fname,"w") : stdout; if ( !args->out ) error("Failed to write to %s: %s\n", !strcmp("-",args->output_fname)?"standard output":args->output_fname,strerror(errno)); fprintf(args->out,"# This file was produced by: bcftools +csq(%s+htslib-%s)\n", bcftools_version(),hts_version()); fprintf(args->out,"# The command line was:\tbcftools +%s", args->argv[0]); int i; for (i=1; iargc; i++) fprintf(args->out," %s",args->argv[i]); fprintf(args->out,"\n"); fprintf(args->out,"# LOG\t[2]Message\n"); fprintf(args->out,"# CSQ"); i = 1; fprintf(args->out,"\t[%d]Sample", ++i); fprintf(args->out,"\t[%d]Haplotype", ++i); fprintf(args->out,"\t[%d]Chromosome", ++i); fprintf(args->out,"\t[%d]Position", ++i); fprintf(args->out,"\t[%d]Consequence", ++i); fprintf(args->out,"\n"); } else { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("[%s] Error: cannot write to %s: %s\n", __func__,args->output_fname? args->output_fname : "standard output", strerror(errno)); if ( args->n_threads > 0) hts_set_opt(args->out_fh, HTS_OPT_THREAD_POOL, args->sr->p); if ( args->record_cmd_line ) bcf_hdr_append_version(args->hdr,args->argc,args->argv,"bcftools/csq"); bcf_hdr_printf(args->hdr,"##INFO=",args->bcsq_tag, args->local_csq ? "Local" : "Haplotype-aware"); if ( args->hdr_nsmpl ) bcf_hdr_printf(args->hdr,"##FORMAT=",args->bcsq_tag); if ( bcf_hdr_write(args->out_fh, args->hdr)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->output_fname?args->output_fname:"standard output"); if ( init_index2(args->out_fh,args->hdr,args->output_fname, &args->index_fn, args->write_index) < 0 ) error("Error: failed to initialise index for %s\n",args->output_fname); } if ( args->verbosity > 0 ) fprintf(stderr,"Calling...\n"); } void destroy_data(args_t *args) { if ( args->ncsq2_small_warned ) fprintf(stderr, "Note: Some samples had too many consequences to be represented in %d bytes. If you need to record them all,\n" " the limit can be increased by running with `--ncsq %d`.\n",ncsq2_to_nfmt(args->ncsq2_max)/8,1+args->ncsq2_small_warned/2); regitr_destroy(args->itr); gff_destroy(args->gff); if ( args->filter ) filter_destroy(args->filter); khp_destroy(trhp,args->active_tr); kh_destroy(pos2vbuf,args->pos2vbuf); if ( args->smpl ) smpl_ilist_destroy(args->smpl); int i,j,ret; if ( args->out_fh ) { if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } ret = hts_close(args->out_fh); } else ret = fclose(args->out); if ( ret ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); for (i=0; ivcf_rbuf.m; i++) { vbuf_t *vbuf = args->vcf_buf[i]; if ( !vbuf ) continue; for (j=0; jm; j++) { if ( !vbuf->vrec[j] ) continue; if ( vbuf->vrec[j]->line ) bcf_destroy(vbuf->vrec[j]->line); free(vbuf->vrec[j]->fmt_bm); free(vbuf->vrec[j]->vcsq); free(vbuf->vrec[j]); } free(vbuf->vrec); free(vbuf); } free(args->vcf_buf); free(args->rm_tr); free(args->csq_buf); free(args->hap->stack); free(args->hap->sseq.s); free(args->hap->tseq.s); free(args->hap->tref.s); free(args->hap); fai_destroy(args->fai); free(args->gt_arr); free(args->str.s); free(args->str2.s); free(args->chr_name); } /* The splice_* functions are for consequences around splice sites: start,stop,splice_* */ #define SPLICE_VAR_REF 0 // ref: ACGT>ACGT, csq not applicable, skip completely #define SPLICE_OUTSIDE 1 // splice acceptor or similar; csq set and is done, does not overlap the region #define SPLICE_INSIDE 2 // overlaps coding region; csq can be set but coding prediction is needed #define SPLICE_OVERLAP 3 // indel overlaps region boundary, csq set but could not determine csq typedef struct { gf_tscript_t *tr; struct { int32_t pos, rlen, alen, ial; char *ref, *alt; bcf1_t *rec; } vcf; uint16_t check_acceptor:1, // check distance from exon start (fwd) or end (rev) check_start:1, // this is the first coding exon (relative to transcript orientation), check first (fwd) or last (rev) codon check_stop:1, // this is the last coding exon (relative to transcript orientation), check last (fwd) or first (rev) codon check_donor:1, // as with check_acceptor check_region_beg:1, // do/don't check for splices at this end, eg. in the first or last exon check_region_end:1, // check_utr:1, // check splice sites (acceptor/donor/region_*) only if not in utr set_refalt:1; // set kref,kalt, if set, check also for synonymous events uint32_t csq; int tbeg, tend; // number of trimmed bases from beg and end of ref,alt allele uint32_t ref_beg, // ref coordinates with spurious bases removed, ACC>AC can become AC>A or CC>C, whichever gives ref_end; // a more conservative csq (the first and last base in kref.s) kstring_t kref, kalt; // trimmed alleles, set only with SPLICE_OLAP } splice_t; void splice_init(splice_t *splice, bcf1_t *rec) { memset(splice,0,sizeof(*splice)); splice->vcf.rec = rec; splice->vcf.pos = rec->pos; splice->vcf.rlen = rec->rlen; splice->vcf.ref = rec->d.allele[0]; splice->csq = 0; } static inline void splice_build_hap(splice_t *splice, uint32_t beg, int len) { // len>0 .. beg is the first base, del filled from right // len<0 .. beg is the last base, del filled from left int rlen, alen, rbeg, abeg; // first base to include (ref coordinates) if ( len<0 ) { rlen = alen = -len; rbeg = beg - rlen + 1; int dlen = splice->vcf.alen - splice->vcf.rlen; if ( dlen<0 && beg < splice->ref_end ) // incomplete del, beg is in the middle dlen += splice->ref_end - beg; abeg = rbeg + dlen; } else { rbeg = abeg = beg; rlen = alen = len; // check for incomplete del as above?? } #define XDBG 0 #if XDBG fprintf(stderr,"build_hap: rbeg=%d + %d abeg=%d \n",rbeg,rlen,abeg); #endif splice->kref.l = 0; splice->kalt.l = 0; // add the part before vcf.ref, in the vcf.ref and after vcf.ref int roff; // how many vcf.ref bases already used if ( rbeg < splice->vcf.pos ) { assert( splice->tr->beg <= rbeg ); // this can be extended thanks to N_REF_PAD kputsn(TSCRIPT_AUX(splice->tr)->ref + N_REF_PAD + rbeg - splice->tr->beg, splice->vcf.pos - rbeg, &splice->kref); roff = 0; } else roff = rbeg - splice->vcf.pos; #if XDBG fprintf(stderr,"r1: %s roff=%d\n",splice->kref.s,roff); #endif if ( roff < splice->vcf.rlen && splice->kref.l < rlen ) { int len = splice->vcf.rlen - roff; // len still available in vcf.ref if ( len > rlen - splice->kref.l ) len = rlen - splice->kref.l; // how much of ref allele is still needed kputsn(splice->vcf.ref + roff, len, &splice->kref); } #if XDBG fprintf(stderr,"r2: %s\n",splice->kref.s); #endif uint32_t end = splice->vcf.pos + splice->vcf.rlen; // position just after the ref allele if ( splice->kref.l < rlen ) { if ( end + rlen - splice->kref.l - 1 > splice->tr->end ) // trim, the requested sequence is too long (could be extended, see N_REF_PAD) rlen -= end + rlen - splice->kref.l - 1 - splice->tr->end; if ( splice->kref.l < rlen ) kputsn(TSCRIPT_AUX(splice->tr)->ref + N_REF_PAD + end - splice->tr->beg, rlen - splice->kref.l, &splice->kref); } #if XDBG fprintf(stderr,"r3: %s\n",splice->kref.s); #endif int aoff; if ( abeg < splice->vcf.pos ) { assert( splice->tr->beg <= abeg ); kputsn(TSCRIPT_AUX(splice->tr)->ref + N_REF_PAD + abeg - splice->tr->beg, splice->vcf.pos - abeg, &splice->kalt); aoff = 0; } else aoff = abeg - splice->vcf.pos; #if XDBG fprintf(stderr,"a1: %s aoff=%d\n",splice->kalt.s,aoff); #endif if ( aoff < splice->vcf.alen && splice->kalt.l < alen ) { int len = splice->vcf.alen - aoff; // len still available in vcf.alt if ( len > alen - splice->kalt.l ) len = alen - splice->kalt.l; // how much of alt allele is still needed kputsn(splice->vcf.alt + aoff, len, &splice->kalt); aoff -= len; } if ( aoff < 0 ) aoff = 0; else aoff--; #if XDBG fprintf(stderr,"a2: %s aoff=%d\n",splice->kalt.s,aoff); #endif end = splice->vcf.pos + splice->vcf.rlen; // position just after the ref allele if ( splice->kalt.l < alen ) { if ( end + alen + aoff - splice->kalt.l - 1 > splice->tr->end ) // trim, the requested sequence is too long alen -= end + alen + aoff - splice->kalt.l - 1 - splice->tr->end; if ( alen > 0 && alen > splice->kalt.l ) kputsn(TSCRIPT_AUX(splice->tr)->ref + aoff + N_REF_PAD + end - splice->tr->beg, alen - splice->kalt.l, &splice->kalt); } #if XDBG fprintf(stderr,"a3: %s\n",splice->kalt.s); fprintf(stderr," [%s]\n [%s]\n\n",splice->kref.s,splice->kalt.s); #endif } void csq_stage(args_t *args, csq_t *csq, bcf1_t *rec); static inline int csq_stage_utr(args_t *args, regitr_t *itr, bcf1_t *rec, uint32_t trid, uint32_t type, int ial) { while ( regitr_overlap(itr) ) { gf_utr_t *utr = regitr_payload(itr, gf_utr_t*); gf_tscript_t *tr = utr->tr; if ( tr->id != trid ) continue; csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.type = (utr->which==prime5 ? CSQ_UTR5 : CSQ_UTR3) | type; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.vcf_ial = ial; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); return csq.type.type; } return 0; } static inline void csq_stage_splice(args_t *args, bcf1_t *rec, gf_tscript_t *tr, uint32_t type, int ial) { #if XDBG fprintf(stderr,"csq_stage_splice %d: type=%d\n",(int)rec->pos+1,type); #endif if ( !type ) return; csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.type = type; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.vcf_ial = ial; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); } static inline const char *drop_chr_prefix(args_t *args, const char *chr) { if ( !args->unify_chr_names ) return chr; if ( !strncasecmp("chr",chr,3) ) return chr+3; return chr; } static inline const char *add_chr_prefix(args_t *args, const char *chr) { if ( !args->unify_chr_names ) return chr; int len = strlen(chr); hts_expand(char,len+4,args->mchr_name,args->chr_name); memcpy(args->chr_name,"chr",3); memcpy(args->chr_name+3,chr,len+1); return args->chr_name; } static inline int splice_csq_ins(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) { // coordinates that matter for consequences, eg AC>ACG trimmed to C>CG, 1bp // before and after the inserted bases if ( splice->tbeg || splice->vcf.ref[0]!=splice->vcf.alt[0] ) { splice->ref_beg = splice->vcf.pos + splice->tbeg - 1; splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend; } else { if ( splice->tend ) splice->tend--; splice->ref_beg = splice->vcf.pos; splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend; } #if XDBG fprintf(stderr,"ins: %s>%s .. ex=%d,%d beg,end=%d,%d tbeg,tend=%d,%d check_utr=%d start,stop,beg,end=%d,%d,%d,%d\n", splice->vcf.ref,splice->vcf.alt,ex_beg,ex_end,splice->ref_beg,splice->ref_end,splice->tbeg,splice->tend,splice->check_utr,splice->check_start,splice->check_stop,splice->check_region_beg,splice->check_region_end); #endif int ret; if ( splice->ref_beg >= ex_end ) // fully outside, beyond the exon { if ( splice->check_utr ) { regitr_t *itr = regitr_init(NULL); const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,splice->vcf.rec)); if ( regidx_overlap(args->idx_utr,chr,splice->ref_beg+1,splice->ref_beg+1, itr) ) // adjacent utr { ret = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id, splice->csq, splice->vcf.ial); if ( ret!=0 ) { regitr_destroy(itr); return SPLICE_OUTSIDE; // overlaps utr } } regitr_destroy(itr); } if ( !splice->check_region_end ) return SPLICE_OUTSIDE; char *ref = NULL, *alt = NULL; if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available { splice_build_hap(splice, ex_end+1, N_SPLICE_REGION_INTRON); ref = splice->kref.s, alt = splice->kalt.s; } if ( splice->ref_beg < ex_end + N_SPLICE_REGION_INTRON && splice->ref_end > ex_end + N_SPLICE_DONOR ) { splice->csq |= CSQ_SPLICE_REGION; if ( ref && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } if ( splice->ref_beg < ex_end + N_SPLICE_DONOR ) { if ( splice->check_donor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_DONOR; if ( splice->check_acceptor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_ACCEPTOR; if ( ref && !strncmp(ref,alt,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_OUTSIDE; } if ( splice->ref_end < ex_beg || (splice->ref_end == ex_beg && !splice->check_region_beg) ) // fully outside, before the exon { if ( splice->check_utr ) { regitr_t *itr = regitr_init(NULL); const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,splice->vcf.rec)); if ( regidx_overlap(args->idx_utr,chr,splice->ref_end-1,splice->ref_end-1, itr) ) // adjacent utr { ret = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id, splice->csq, splice->vcf.ial); if ( ret!=0 ) { regitr_destroy(itr); return SPLICE_OUTSIDE; // overlaps utr } } regitr_destroy(itr); } if ( !splice->check_region_beg ) return SPLICE_OUTSIDE; char *ref = NULL, *alt = NULL; if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available { splice_build_hap(splice, ex_beg - N_SPLICE_REGION_INTRON, N_SPLICE_REGION_INTRON); ref = splice->kref.s, alt = splice->kalt.s; } if ( splice->ref_end > ex_beg - N_SPLICE_REGION_INTRON && splice->ref_beg < ex_beg - N_SPLICE_DONOR ) { splice->csq |= CSQ_SPLICE_REGION; if ( ref && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } if ( splice->ref_end > ex_beg - N_SPLICE_DONOR ) { if ( splice->check_donor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_DONOR; if ( splice->check_acceptor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_ACCEPTOR; if ( ref && !strncmp(ref+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,alt+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_OUTSIDE; } // overlaps the exon or inside the exon // possible todo: find better alignment for frameshifting variants? if ( splice->ref_beg <= ex_beg + 2 ) // in the first 3bp { if ( splice->check_region_beg ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } } if ( splice->ref_end > ex_end - 2 ) { if ( splice->check_region_end ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } } if ( splice->set_refalt ) { // Make sure the variant will not end up left aligned to avoid overlapping vcf records // splice_build_hap(splice, splice->ref_beg, splice->vcf.alen - splice->tend - splice->tbeg + 1); // splice->vcf.rlen -= splice->tbeg + splice->tend - 1; // if ( splice->kref.l > splice->vcf.rlen ) { splice->kref.l = splice->vcf.rlen; splice->kref.s[splice->kref.l] = 0; } if ( splice->ref_beg < splice->vcf.pos ) // this must have been caused by too much trimming from right { int dlen = splice->vcf.pos - splice->ref_beg; assert( dlen==1 ); splice->tbeg += dlen; if ( splice->tbeg + splice->tend == splice->vcf.rlen ) splice->tend -= dlen; splice->ref_beg = splice->vcf.pos; } if ( splice->ref_end==ex_beg ) splice->tend--; // prevent zero-length ref allele splice_build_hap(splice, splice->ref_beg, splice->vcf.alen - splice->tend - splice->tbeg + 1); splice->vcf.rlen -= splice->tbeg + splice->tend - 1; if ( splice->kref.l > splice->vcf.rlen ) { splice->kref.l = splice->vcf.rlen; splice->kref.s[splice->kref.l] = 0; } } csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_INSIDE; } int shifted_del_synonymous(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) { static int small_ref_padding_warned = 0; gf_tscript_t *tr = splice->tr; // We know the VCF record overlaps the exon, but does it overlap the start codon? if ( tr->strand==STRAND_REV && splice->vcf.pos + splice->vcf.rlen + 2 <= ex_end ) return 0; if ( tr->strand==STRAND_FWD && splice->vcf.pos >= ex_beg + 3 ) return 0; #if XDBG fprintf(stderr,"shifted_del_synonymous: %d-%d %s\n",ex_beg,ex_end, tr->strand==STRAND_FWD?"fwd":(tr->strand==STRAND_REV?"rev":"unk")); fprintf(stderr," %d .. %s > %s\n",splice->vcf.pos+1,splice->vcf.ref,splice->vcf.alt); #endif // is there enough ref sequence for the extension? All coordinates are 0-based int ref_len = strlen(splice->vcf.ref); int alt_len = strlen(splice->vcf.alt); assert( ref_len > alt_len ); int ndel = ref_len - alt_len; if ( tr->strand==STRAND_REV ) { int32_t vcf_ref_end = splice->vcf.pos + ref_len - 1; // end pos of the VCF REF allele int32_t tr_ref_end = splice->tr->end + N_REF_PAD; // the end pos of accessible cached ref seq if ( vcf_ref_end + ndel > tr_ref_end ) { if ( !small_ref_padding_warned ) { fprintf(stderr,"Warning: Could not verify synonymous start/stop at %s:%d due to small N_REF_PAD. (Improve me?)\n",bcf_seqname(args->hdr,splice->vcf.rec),splice->vcf.pos+1); small_ref_padding_warned = 1; } return 0; } char *ptr_vcf = splice->vcf.ref + alt_len; // the first deleted base in the VCF REF allele char *ptr_ref = TSCRIPT_AUX(splice->tr)->ref + N_REF_PAD + (vcf_ref_end + 1 - splice->tr->beg); // the first ref base after the ndel bases deleted #if XDBG fprintf(stderr,"vcf: %s\nref: %s\n",ptr_vcf,ptr_ref); #endif int i = 0; while ( ptr_vcf[i] && ptr_vcf[i]==ptr_ref[i] ) i++; if ( ptr_vcf[i] ) return 0; // the deleted sequence cannot be replaced } else if ( tr->strand==STRAND_FWD ) { // STRAND_FWD int32_t vcf_block_beg = splice->vcf.pos + ref_len - 2*ndel; // the position of the first base of the ref block that could potentially replace the deletion if ( vcf_block_beg < 0 ) return 0; #if XDBG fprintf(stderr,"vcf_block_beg: %d\n",vcf_block_beg+1); #endif if ( N_REF_PAD + vcf_block_beg < ex_beg ) { if ( !small_ref_padding_warned ) { fprintf(stderr,"Warning: Could not verify synonymous start/stop at %s:%d due to small N_REF_PAD. (Improve me?)\n",bcf_seqname(args->hdr,splice->vcf.rec),splice->vcf.pos+1); small_ref_padding_warned = 1; } return 0; } char *ptr_vcf = splice->vcf.ref + alt_len; // the first deleted base in the VCF REF allele char *ptr_ref = TSCRIPT_AUX(splice->tr)->ref + N_REF_PAD + vcf_block_beg - splice->tr->beg; // the replacement ref block #if XDBG fprintf(stderr,"vcf: %s\nref: %s\n",ptr_vcf,ptr_ref); #endif int i = 0; while ( ptr_vcf[i] && ptr_vcf[i]==ptr_ref[i] ) i++; if ( ptr_vcf[i] ) return 0; // the deleted sequence cannot be replaced } return 1; } static inline int splice_csq_del(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) { if ( splice->check_start ) { // check for synonymous start // test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.txt // test/csq/ENST00000368801.2/start-lost.txt // test/csq/ENST00000318249.2/synonymous-start-lost.txt int is_synonymous = shifted_del_synonymous(args, splice, ex_beg, ex_end); if ( is_synonymous ) { splice->csq |= CSQ_START_RETAINED; return SPLICE_OVERLAP; } } // coordinates that matter for consequences, eg AC>ACG trimmed to C>CG splice->ref_beg = splice->vcf.pos + splice->tbeg - 1; // 1b before the deleted base splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend - 1; // the last deleted base #if XDBG fprintf(stderr,"splice_csq_del: %s>%s .. ex=%d,%d beg,end=%d,%d tbeg,tend=%d,%d check_utr=%d start,stop,beg,end=%d,%d,%d,%d\n", splice->vcf.ref,splice->vcf.alt,ex_beg,ex_end,splice->ref_beg,splice->ref_end,splice->tbeg,splice->tend,splice->check_utr,splice->check_start,splice->check_stop,splice->check_region_beg,splice->check_region_end); #endif if ( splice->ref_beg + 1 < ex_beg ) // the part before the exon; ref_beg is off by -1 { if ( splice->check_region_beg ) { int csq = 0; if ( splice->check_utr ) { regitr_t *itr = regitr_init(NULL); const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,splice->vcf.rec)); if ( regidx_overlap(args->idx_utr,chr,splice->ref_beg,ex_beg-1, itr) ) // adjacent utr csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id, splice->csq, splice->vcf.ial); regitr_destroy(itr); } if ( !csq ) { char *ref = NULL, *alt = NULL; if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available { // filling from the left does not work for ENST00000341065/frame3.vcf // CAG.GTGGCCAG CAG.GTGGCCAG // CA-.--GGCCAG vs CAG.---GCCAG // splice_build_hap(splice, ex_beg-1, -N_SPLICE_REGION_INTRON); // // filling from the right: splice_build_hap(splice, ex_beg - N_SPLICE_REGION_INTRON, N_SPLICE_REGION_INTRON); ref = splice->kref.s, alt = splice->kalt.s; } if ( splice->ref_end >= ex_beg - N_SPLICE_REGION_INTRON && splice->ref_beg < ex_beg - N_SPLICE_DONOR ) { splice->csq |= CSQ_SPLICE_REGION; if ( ref && alt && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } if ( splice->ref_end >= ex_beg - N_SPLICE_DONOR ) { if ( splice->check_donor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_DONOR; if ( splice->check_acceptor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_ACCEPTOR; if ( ref && alt && !strncmp(ref+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,alt+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } } } if ( splice->ref_end >= ex_beg ) { splice->tbeg = splice->ref_beg - splice->vcf.pos + 1; splice->ref_beg = ex_beg - 1; if ( splice->tbeg + splice->tend == splice->vcf.alen ) { // the deletion overlaps ex_beg and cannot be easily realigned to the right if ( !splice->tend ) { splice->csq |= CSQ_CODING_SEQUENCE; return SPLICE_OVERLAP; } splice->tend--; } } } if ( ex_end < splice->ref_end ) // the part after the exon { if ( splice->check_region_end ) { int csq = 0; if ( splice->check_utr ) { regitr_t *itr = regitr_init(NULL); const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,splice->vcf.rec)); if ( regidx_overlap(args->idx_utr,chr,ex_end+1,splice->ref_end, itr) ) // adjacent utr csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id, splice->csq, splice->vcf.ial); regitr_destroy(itr); } if ( !csq ) { char *ref = NULL, *alt = NULL; if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available { splice_build_hap(splice, ex_end+1, N_SPLICE_REGION_INTRON); // ref,alt positioned at the first intron base ref = splice->kref.s, alt = splice->kalt.s; } if ( splice->ref_beg < ex_end + N_SPLICE_REGION_INTRON && splice->ref_end > ex_end + N_SPLICE_DONOR ) { splice->csq |= CSQ_SPLICE_REGION; if ( ref && alt && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } if ( splice->ref_beg < ex_end + N_SPLICE_DONOR ) { if ( splice->check_donor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_DONOR; if ( splice->check_acceptor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_ACCEPTOR; if ( ref && alt && !strncmp(ref+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,alt+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; } } } if ( splice->ref_beg < ex_end ) { splice->tend = splice->vcf.rlen - (splice->ref_end - splice->vcf.pos + 1); splice->ref_end = ex_end; } } if ( splice->ref_end < ex_beg || splice->ref_beg >= ex_end ) { csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_OUTSIDE; } if ( splice->ref_beg < ex_beg + 2 ) // ref_beg is off by -1 { if ( splice->check_region_beg ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } } if ( splice->ref_end > ex_end - 3 ) { if ( splice->check_region_end ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } } if ( splice->set_refalt ) { if ( splice->tbeg>0 ) splice->tbeg--; //why is this? if ( splice->vcf.rlen > splice->tbeg + splice->tend && splice->vcf.alen > splice->tbeg + splice->tend ) { splice->vcf.rlen -= splice->tbeg + splice->tend; splice->vcf.alen -= splice->tbeg + splice->tend; } splice->kref.l = 0; kputsn(splice->vcf.ref + splice->tbeg, splice->vcf.rlen, &splice->kref); splice->kalt.l = 0; kputsn(splice->vcf.alt + splice->tbeg, splice->vcf.alen, &splice->kalt); if ( (splice->ref_beg+1 < ex_beg && splice->ref_end >= ex_beg) || (splice->ref_beg+1 < ex_end && splice->ref_end >= ex_end) ) // ouch, ugly ENST00000409523/long-overlapping-del.vcf { int ref_beg = splice->ref_beg + splice->kalt.l - 1; // 0 for AAA>A, 1 for AAA>AC if ( ref_beg < splice->ref_end ) splice->csq |= (splice->ref_end - ref_beg)%3 ? CSQ_FRAMESHIFT_VARIANT : CSQ_INFRAME_DELETION; return SPLICE_OVERLAP; } } csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_INSIDE; } static inline int splice_csq_mnp(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) { // not a real variant, can be ignored: eg ACGT>ACGT if ( splice->tbeg + splice->tend == splice->vcf.rlen ) return SPLICE_VAR_REF; splice->ref_beg = splice->vcf.pos + splice->tbeg; splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend - 1; #if XDBG fprintf(stderr,"mnp: %s>%s .. ex=%d,%d beg,end=%d,%d tbeg,tend=%d,%d check_utr=%d start,stop,beg,end=%d,%d,%d,%d\n", splice->vcf.ref,splice->vcf.alt,ex_beg,ex_end,splice->ref_beg,splice->ref_end,splice->tbeg,splice->tend,splice->check_utr,splice->check_start,splice->check_stop,splice->check_region_beg,splice->check_region_end); #endif if ( splice->ref_beg < ex_beg ) // the part before the exon { if ( splice->check_region_beg ) { int csq = 0; if ( splice->check_utr ) { regitr_t *itr = regitr_init(NULL); const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,splice->vcf.rec)); if ( regidx_overlap(args->idx_utr,chr,splice->ref_beg,ex_beg-1, itr) ) // adjacent utr csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id, splice->csq, splice->vcf.ial); regitr_destroy(itr); } if ( !csq ) { if ( splice->ref_end >= ex_beg - N_SPLICE_REGION_INTRON && splice->ref_beg < ex_beg - N_SPLICE_DONOR ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->ref_end >= ex_beg - N_SPLICE_DONOR ) { if ( splice->check_donor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_DONOR; if ( splice->check_acceptor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_ACCEPTOR; } } } if ( splice->ref_end >= ex_beg ) { splice->tbeg = splice->ref_beg - splice->vcf.pos; splice->ref_beg = ex_beg; } } if ( ex_end < splice->ref_end ) // the part after the exon { if ( splice->check_region_end ) { int csq = 0; if ( splice->check_utr ) { regitr_t *itr = regitr_init(NULL); const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,splice->vcf.rec)); if ( regidx_overlap(args->idx_utr,chr,ex_end+1,splice->ref_end, itr) ) // adjacent utr csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id, splice->csq, splice->vcf.ial); regitr_destroy(itr); } if ( !csq ) { if ( splice->ref_beg <= ex_end + N_SPLICE_REGION_INTRON && splice->ref_end > ex_end + N_SPLICE_DONOR ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->ref_beg <= ex_end + N_SPLICE_DONOR ) { if ( splice->check_donor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_DONOR; if ( splice->check_acceptor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_ACCEPTOR; } } } if ( splice->ref_beg <= ex_end ) { splice->tend = splice->vcf.rlen - (splice->ref_end - splice->vcf.pos + 1); splice->ref_end = ex_end; } } if ( splice->ref_end < ex_beg || splice->ref_beg > ex_end ) { csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_OUTSIDE; } if ( splice->ref_beg < ex_beg + 3 ) { if ( splice->check_region_beg ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } else if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } } if ( splice->ref_end > ex_end - 3 ) { if ( splice->check_region_end ) splice->csq |= CSQ_SPLICE_REGION; if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } else if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } } if ( splice->set_refalt ) { splice->vcf.rlen -= splice->tbeg + splice->tend; splice->kref.l = 0; kputsn(splice->vcf.ref + splice->tbeg, splice->vcf.rlen, &splice->kref); splice->kalt.l = 0; kputsn(splice->vcf.alt + splice->tbeg, splice->vcf.rlen, &splice->kalt); } csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq, splice->vcf.ial); return SPLICE_INSIDE; } static inline int splice_csq(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) { splice->vcf.alen = strlen(splice->vcf.alt); int rlen1 = splice->vcf.rlen - 1, alen1 = splice->vcf.alen - 1, i = 0; splice->tbeg = 0, splice->tend = 0; // trim from the right, then from the left while ( i<=rlen1 && i<=alen1 ) { if ( splice->vcf.ref[rlen1-i] != splice->vcf.alt[alen1-i] ) break; i++; } splice->tend = i; rlen1 -= i, alen1 -= i, i = 0; while ( i<=rlen1 && i<=alen1 ) { if ( splice->vcf.ref[i] != splice->vcf.alt[i] ) break; i++; } splice->tbeg = i; // The mnp, ins and del code was split into near-identical functions for clarity and debugging; // possible todo: generalize once stable if ( splice->vcf.rlen==splice->vcf.alen ) return splice_csq_mnp(args, splice, ex_beg, ex_end); if ( splice->vcf.rlen < splice->vcf.alen ) return splice_csq_ins(args, splice, ex_beg, ex_end); if ( splice->vcf.rlen > splice->vcf.alen ) return splice_csq_del(args, splice, ex_beg, ex_end); return 0; } // return value: 0 added, 1 overlapping variant, 2 silent discard (intronic,alt=ref) int hap_init(args_t *args, hap_node_t *parent, hap_node_t *child, gf_cds_t *cds, bcf1_t *rec, int ial) { int i; kstring_t str = {0,0,0}; gf_tscript_t *tr = cds->tr; child->icds = cds->icds; // index of cds in the tscript's list of exons child->vcf_ial = ial; splice_t splice; splice_init(&splice, rec); splice.tr = tr; splice.vcf.ial = ial; splice.vcf.alt = rec->d.allele[ial]; splice.check_acceptor = splice.check_donor = splice.set_refalt = splice.check_utr = 1; if ( !(tr->trim & TRIM_5PRIME) ) { if ( tr->strand==STRAND_FWD ) { if ( child->icds==0 ) splice.check_start = 1; } else if ( tr->strand==STRAND_REV ) { if ( child->icds==tr->ncds-1 ) splice.check_start = 1; } } if ( !(tr->trim & TRIM_3PRIME) ) { if ( tr->strand==STRAND_FWD ) { if ( child->icds==tr->ncds-1 ) splice.check_stop = 1; } else if ( tr->strand==STRAND_REV ) { if ( child->icds==0 ) splice.check_stop = 1; } } if ( splice.check_start ) // do not check starts in incomplete CDS, defined as not starting with M { if ( tr->strand==STRAND_FWD ) { if ( dna2aa(TSCRIPT_AUX(tr)->ref+N_REF_PAD+cds->beg-tr->beg) != 'M' ) splice.check_start = 0; } else if ( tr->strand==STRAND_REV ) { if ( cdna2aa(TSCRIPT_AUX(tr)->ref+N_REF_PAD+cds->beg-tr->beg+cds->len-3) != 'M' ) splice.check_start = 0; } } if ( child->icds!=0 ) splice.check_region_beg = 1; if ( child->icds!=tr->ncds-1 ) splice.check_region_end = 1; #if XDBG fprintf(stderr,"\nhap_init: %d [%s][%s] check start:%d,stop:%d\n",splice.vcf.pos+1,splice.vcf.ref,splice.vcf.alt,splice.check_start,splice.check_stop); #endif int ret = splice_csq(args, &splice, cds->beg, cds->beg + cds->len - 1); #if XDBG fprintf(stderr,"cds splice_csq: %d [%s][%s] .. beg,end=%d %d, ret=%d, csq=%d\n\n",splice.vcf.pos+1,splice.kref.s,splice.kalt.s,splice.ref_beg+1,splice.ref_end+1,ret,splice.csq); #endif if ( ret==SPLICE_VAR_REF ) return 2; // not a variant, eg REF=CA ALT=CA if ( ret==SPLICE_OUTSIDE || ret==SPLICE_OVERLAP || splice.csq==CSQ_START_LOST ) // not a coding csq { free(splice.kref.s); free(splice.kalt.s); if ( !splice.csq ) return 2; // fully intronic, no csq // splice_region/acceptor/donor child->seq = NULL; child->sbeg = 0; child->rbeg = rec->pos; child->rlen = 0; child->dlen = 0; kputs(rec->d.allele[0],&str); kputc('>',&str); kputs(rec->d.allele[ial],&str); child->var = str.s; child->type = HAP_SSS; child->csq = splice.csq; child->rec = rec; return 0; } if ( splice.csq & CSQ_SYNONYMOUS_VARIANT ) splice.csq &= ~CSQ_SYNONYMOUS_VARIANT; // synonymous&splice,frame could become synonymous&frame,splice int dbeg = 0; if ( splice.ref_beg < cds->beg ) { // The vcf record overlaps the exon boundary, but the variant itself // should fit inside since we are here. This will need more work. // #1475227917 dbeg = cds->beg - splice.ref_beg; splice.kref.l -= dbeg; splice.ref_beg = cds->beg; assert( dbeg <= splice.kalt.l ); } assert( parent->type!=HAP_SSS ); if ( parent->type==HAP_CDS ) { i = parent->icds; if ( i!=cds->icds ) { // the variant is on a new exon, finish up the previous int len = tr->cds[i]->len - parent->rbeg - parent->rlen + tr->cds[i]->beg; if ( len > 0 ) kputsn_(TSCRIPT_AUX(tr)->ref + N_REF_PAD + parent->rbeg + parent->rlen - tr->beg, len, &str); } // append any skipped non-variant exons while ( ++i < cds->icds ) kputsn_(TSCRIPT_AUX(tr)->ref + N_REF_PAD + tr->cds[i]->beg - tr->beg, tr->cds[i]->len, &str); if ( parent->icds==child->icds ) { int len = splice.ref_beg - parent->rbeg - parent->rlen; if ( len < 0 ) // overlapping variants { free(str.s); free(splice.kref.s); free(splice.kalt.s); return 1; } kputsn_(TSCRIPT_AUX(tr)->ref + N_REF_PAD + parent->rbeg + parent->rlen - tr->beg, len, &str); } else kputsn_(TSCRIPT_AUX(tr)->ref + N_REF_PAD + cds->beg - tr->beg, splice.ref_beg - cds->beg, &str); } kputs(splice.kalt.s + dbeg, &str); child->seq = str.s; child->sbeg = cds->pos + (splice.ref_beg - cds->beg); child->rbeg = splice.ref_beg; child->rlen = splice.kref.l; child->type = HAP_CDS; child->prev = parent; child->rec = rec; child->csq = splice.csq; // set vlen and the "ref>alt" string { int rlen = strlen(rec->d.allele[0]); int alen = strlen(rec->d.allele[ial]); child->dlen = alen - rlen; child->var = (char*) malloc(rlen+alen+2); memcpy(child->var,rec->d.allele[0],rlen); child->var[rlen] = '>'; memcpy(child->var+rlen+1,rec->d.allele[ial],alen); child->var[rlen+alen+1] = 0; } // yuck, the whole CDS is modified/deleted, not ready for this, todo. if ( child->rbeg + child->rlen > cds->beg + cds->len ) { child->type = HAP_SSS; if ( !child->csq ) child->csq |= CSQ_CODING_SEQUENCE; // hack, specifically for ENST00000390520/deletion-overlap.vcf } free(splice.kref.s); free(splice.kalt.s); return 0; } void hap_destroy(hap_node_t *hap) { int i; for (i=0; inchild; i++) if ( hap->child[i] ) hap_destroy(hap->child[i]); for (i=0; imcsq_list; i++) free(hap->csq_list[i].type.vstr.s); free(hap->csq_list); free(hap->child); free(hap->cur_child); free(hap->seq); free(hap->var); free(hap); } /* ref: spliced reference and its length (ref.l) seq: part of the spliced query transcript on the reference strand to translate, its length (seq.l) and the total length of the complete transcript (seq.m) sbeg: seq offset within the spliced query transcript rbeg: seq offset within ref, 0-based rend: last base of seq within ref, plus one. If seq does not contain indels, it is rend=rbeg+seq->l strand: coding strand - 0:rev, 1:fwd tseq: translated sequence (aa) fill: frameshift, fill until the end (strand=fwd) or from the start (strand=rev) */ void cds_translate(kstring_t *_ref, kstring_t *_seq, uint32_t sbeg, uint32_t rbeg, uint32_t rend, int strand, kstring_t *tseq, int fill) { #if XDBG fprintf(stderr,"\ntranslate: %d %d %d fill=%d seq.l=%d\n",sbeg,rbeg,rend,fill,(int)_seq->l); #endif char tmp[3], *codon, *end; int i, len, npad; kstring_t ref = *_ref; kstring_t seq = *_seq; tseq->l = 0; if ( !seq.l ) { kputc('?', tseq); return; } #define DBG 0 #if DBG fprintf(stderr,"translate: sbeg,rbeg,rend=%d %d %d fill=%d seq.l=%d\n",sbeg,rbeg,rend,fill,(int)_seq->l); fprintf(stderr," ref: l=%d %s\n", (int)ref.l,ref.s); fprintf(stderr," seq: l=%d m=%d ", (int)seq.l,(int)seq.m); for (i=0; i1 fprintf(stderr," npad: %d\n",npad); #endif assert( npad<=rbeg ); for (i=0; i1 fprintf(stderr,"\t i=%d\n", i); #endif if ( i==3 ) { kputc_(dna2aa(tmp), tseq); #if DBG>1 fprintf(stderr,"[1]%c%c%c\n",tmp[0],tmp[1],tmp[2]); #endif codon = seq.s + 3 - npad; // next codon end = codon + len - 1 - (len % 3); // last position of a valid codon while ( codon < end ) { kputc_(dna2aa(codon), tseq); #if DBG>1 fprintf(stderr,"[2]%c%c%c\n",codon[0],codon[1],codon[2]); #endif codon += 3; } end = seq.s + seq.l - 1; for (i=0; codon+i<=end; i++) tmp[i] = codon[i]; } // right padding codon = ref.s + rend + N_REF_PAD; if ( i>0 ) { #if DBG>1 if(i==1)fprintf(stderr,"[3]%c\n",tmp[0]); if(i==2)fprintf(stderr,"[3]%c%c\n",tmp[0],tmp[1]); #endif for (; i<3; i++) { tmp[i] = *codon; codon++; } kputc_(dna2aa(tmp), tseq); #if DBG>1 fprintf(stderr,"[4]%c%c%c\n",tmp[0],tmp[1],tmp[2]); #endif } if ( fill!=0 ) { end = ref.s + ref.l - N_REF_PAD; while ( codon+3 <= end ) { kputc_(dna2aa(codon), tseq); #if DBG>1 fprintf(stderr,"[5]%c%c%c\t%c\n",codon[0],codon[1],codon[2],dna2aa(codon)); #endif codon += 3; } } } else if ( strand==STRAND_REV ) { // right padding - number of bases to take from ref npad = (seq.m - (sbeg + seq.l)) % 3; #if DBG>1 fprintf(stderr," npad: %d\n",npad); #endif if ( !(npad>=0 && sbeg+seq.l+npad<=seq.m) ) fprintf(stderr,"sbeg=%d seq.l=%d seq.m=%d npad=%d\n",sbeg,(int)seq.l,(int)seq.m,npad); assert( npad>=0 && sbeg+seq.l+npad<=seq.m ); // todo: first codon on the rev strand if ( npad==2 ) { tmp[1] = ref.s[rend+N_REF_PAD]; tmp[2] = ref.s[rend+N_REF_PAD+1]; i = 0; } else if ( npad==1 ) { tmp[2] = ref.s[rend+N_REF_PAD]; i = 1; } else i = 2; end = seq.s + seq.l; for (; i>=0 && end>seq.s; i--) tmp[i] = *(--end); #if DBG>1 fprintf(stderr,"\t i=%d\n", i); if(i==1)fprintf(stderr,"[0] %c\n",tmp[2]); if(i==0)fprintf(stderr,"[0] %c%c\n",tmp[1],tmp[2]); #endif if ( i==-1 ) { #if DBG>1 fprintf(stderr,"[1]%c%c%c\t%c\n",tmp[0],tmp[1],tmp[2], cdna2aa(tmp)); #endif kputc_(cdna2aa(tmp), tseq); codon = end - 3; while ( codon >= seq.s ) { kputc_(cdna2aa(codon), tseq); #if DBG>1 fprintf(stderr,"[2]%c%c%c\t%c\n",codon[0],codon[1],codon[2], cdna2aa(codon)); #endif codon -= 3; } if ( seq.s-codon==2 ) { tmp[2] = seq.s[0]; i = 1; } else if ( seq.s-codon==1 ) { tmp[1] = seq.s[0]; tmp[2] = seq.s[1]; i = 0; } else i = -1; #if DBG>1 if(i==1)fprintf(stderr,"[3] %c\n",tmp[2]); if(i==0)fprintf(stderr,"[3] %c%c\n",tmp[1],tmp[2]); #endif } // left padding end = ref.s + N_REF_PAD + rbeg; if ( i>=0 ) { for (; i>=0 && end>=ref.s; i--) tmp[i] = *(--end); kputc_(cdna2aa(tmp), tseq); #if DBG>1 fprintf(stderr,"[4]%c%c%c\t%c\n",tmp[0],tmp[1],tmp[2],cdna2aa(tmp)); #endif } if ( fill!=0 ) { codon = end - 3; while ( codon >= ref.s + N_REF_PAD ) { kputc_(cdna2aa(codon), tseq); #if DBG>1 fprintf(stderr,"[5]%c%c%c\t%c\n",codon[0],codon[1],codon[2],cdna2aa(codon)); #endif codon -= 3; } } } else error("Should not happen: %d\n", strand); kputc_(0,tseq); tseq->l--; #if DBG fprintf(stderr," tseq: %s\n", tseq->s); #endif } void tscript_splice_ref(gf_tscript_t *tr) { int i, len = 0; for (i=0; incds; i++) len += tr->cds[i]->len; TSCRIPT_AUX(tr)->nsref = len + 2*N_REF_PAD; TSCRIPT_AUX(tr)->sref = (char*) malloc(len + 1 + 2*N_REF_PAD); len = 0; memcpy(TSCRIPT_AUX(tr)->sref, TSCRIPT_AUX(tr)->ref + tr->cds[0]->beg - tr->beg, N_REF_PAD); len += N_REF_PAD; for (i=0; incds; i++) { memcpy(TSCRIPT_AUX(tr)->sref + len, TSCRIPT_AUX(tr)->ref + N_REF_PAD + tr->cds[i]->beg - tr->beg, tr->cds[i]->len); len += tr->cds[i]->len; } memcpy(TSCRIPT_AUX(tr)->sref + len, TSCRIPT_AUX(tr)->ref + N_REF_PAD + tr->cds[tr->ncds-1]->beg - tr->beg, N_REF_PAD); len += N_REF_PAD; TSCRIPT_AUX(tr)->sref[len] = 0; } // returns: 0 if consequence was added, 1 if it already exists or could not be added int csq_push(args_t *args, csq_t *csq, bcf1_t *rec) { #if XDBG fprintf(stderr,"csq_push: %d .. %d\n",(int)rec->pos+1,csq->type.type); #endif khint_t k = kh_get(pos2vbuf, args->pos2vbuf, (int)csq->pos); vbuf_t *vbuf = (k == kh_end(args->pos2vbuf)) ? NULL : kh_val(args->pos2vbuf, k); if ( !vbuf ) error("This should not happen. %s:%d %s\n",bcf_seqname(args->hdr,rec),csq->pos+1,csq->type.vstr.s); int i; for (i=0; in; i++) if ( vbuf->vrec[i]->line==rec ) break; if ( i==vbuf->n ) error("This should not happen.. %s:%d %s\n", bcf_seqname(args->hdr,rec),csq->pos+1,csq->type.vstr.s); vrec_t *vrec = vbuf->vrec[i]; // if the variant overlaps donor/acceptor and also splice region, report only donor/acceptor if ( csq->type.type & CSQ_SPLICE_REGION && csq->type.type & (CSQ_SPLICE_DONOR|CSQ_SPLICE_ACCEPTOR) ) csq->type.type &= ~CSQ_SPLICE_REGION; if ( csq->type.type & CSQ_PRINTED_UPSTREAM ) { for (i=0; invcsq; i++) { // Same as below, to avoid records like // 3630 .. @3632,stop_lost|AL627309.1|ENST00000423372|protein_coding|- // 3632 .. stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C if ( csq->type.type&CSQ_START_STOP && vrec->vcsq[i].type&CSQ_START_STOP ) { vrec->vcsq[i] = csq->type; goto exit_duplicate; } if ( !(vrec->vcsq[i].type & CSQ_PRINTED_UPSTREAM) ) continue; if ( csq->type.ref != vrec->vcsq[i].ref ) continue; goto exit_duplicate; } } else if ( csq->type.type & CSQ_COMPOUND ) { for (i=0; invcsq; i++) { if ( csq->type.trid != vrec->vcsq[i].trid && (csq->type.type|vrec->vcsq[i].type)&CSQ_PRN_TSCRIPT ) continue; if ( csq->type.biotype != vrec->vcsq[i].biotype ) continue; if ( csq->type.gene != vrec->vcsq[i].gene ) continue; if ( csq->type.vcf_ial != vrec->vcsq[i].vcf_ial ) continue; if ( (csq->type.type&CSQ_UPSTREAM_STOP)^(vrec->vcsq[i].type&CSQ_UPSTREAM_STOP) ) continue; // both must or mustn't have upstream_stop if ( csq->type.vstr.s || vrec->vcsq[i].vstr.s ) { // This is a bit hacky, but we want a simpler and more predictable output. The splice_csq() function // can trigger stop/start events based on indel overlap, then another stop/start event can be triggered // from add_csq() or test_cds_local() based on sequence comparison, and on output we could find two // consequences: // stop_lost|AL627309.1|ENST00000423372|protein_coding|- // stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA if ( !csq->type.vstr.s || !vrec->vcsq[i].vstr.s ) { if ( csq->type.type&CSQ_START_STOP && vrec->vcsq[i].type&CSQ_START_STOP ) { vrec->vcsq[i].type |= csq->type.type; // remove stop_lost&synonymous if stop_retained set if ( vrec->vcsq[i].type&CSQ_STOP_RETAINED ) vrec->vcsq[i].type &= ~(CSQ_STOP_LOST|CSQ_SYNONYMOUS_VARIANT); if ( !vrec->vcsq[i].vstr.s ) vrec->vcsq[i].vstr = csq->type.vstr; goto exit_duplicate; } continue; } if ( strcmp(csq->type.vstr.s,vrec->vcsq[i].vstr.s) ) continue; } vrec->vcsq[i].type |= csq->type.type; goto exit_duplicate; } } else { for (i=0; invcsq; i++) { if ( csq->type.trid != vrec->vcsq[i].trid && (csq->type.type|vrec->vcsq[i].type)&CSQ_PRN_TSCRIPT) continue; if ( csq->type.biotype != vrec->vcsq[i].biotype ) continue; if ( !(vrec->vcsq[i].type & CSQ_COMPOUND) ) { vrec->vcsq[i].type |= csq->type.type; goto exit_duplicate; } if ( vrec->vcsq[i].type==(vrec->vcsq[i].type|csq->type.type) ) goto exit_duplicate; } } // no such csq yet in this vcf record csq->vrec = vrec; csq->idx = vrec->nvcsq++; hts_expand0(vcsq_t, vrec->nvcsq, vrec->mvcsq, vrec->vcsq); vrec->vcsq[i] = csq->type; return 0; exit_duplicate: csq->vrec = vrec; csq->idx = i; return 1; } // soff .. position of the variant within the trimmed query transcript // sbeg .. position of the variant within the query transcript // rbeg .. position on the reference transcript (if there are no indels, then rbeg=send) // rpos .. VCF position #define node2soff(i) (hap->stack[i].slen - (hap->stack[i].node->rlen + hap->stack[i].node->dlen)) #define node2sbeg(i) (hap->sbeg + node2soff(i)) #define node2send(i) (hap->sbeg + hap->stack[i].slen) #define node2rbeg(i) (hap->stack[i].node->sbeg) #define node2rend(i) (hap->stack[i].node->sbeg + hap->stack[i].node->rlen) #define node2rpos(i) (hap->stack[i].node->rec->pos) void kput_vcsq(args_t *args, vcsq_t *csq, kstring_t *str) { // Remove start/stop from incomplete CDS, but only if there is another // consequence as something must be reported if ( csq->type & CSQ_INCOMPLETE_CDS && (csq->type & ~(CSQ_START_STOP|CSQ_INCOMPLETE_CDS|CSQ_UPSTREAM_STOP)) ) csq->type &= ~(CSQ_START_STOP|CSQ_INCOMPLETE_CDS); // Remove missense from start/stops if ( csq->type & CSQ_START_STOP && csq->type & CSQ_MISSENSE_VARIANT ) csq->type &= ~CSQ_MISSENSE_VARIANT; if ( csq->type & CSQ_PRINTED_UPSTREAM && csq->ref ) { kputc_('@',str); kputw(csq->ref->pos+1, str); return; } if ( csq->type & CSQ_UPSTREAM_STOP ) kputc_('*',str); int has_csq = 0, i, n = sizeof(csq_strings)/sizeof(char*); for (i=1; itype&(1<type&(1<biotype==GF_NMD) && (csq->type & CSQ_PRN_NMD) ) { if ( has_csq ) kputc_('&',str); // just in case, this should always be true kputs("NMD_transcript",str); } kputc_('|', str); if ( csq->gene ) kputs(csq->gene , str); kputc_('|', str); // if ( csq->type & CSQ_PRN_TSCRIPT ) kputs(args->tscript_ids.str[csq->trid], str); if ( csq->type & CSQ_PRN_TSCRIPT ) kputs(gff_id2string(args->gff,transcript,csq->trid), str); kputc_('|', str); kputs(gf_type2gff_string(csq->biotype), str); if ( CSQ_PRN_STRAND(csq->type) || csq->vstr.l ) kputs(csq->strand==STRAND_FWD ? "|+" : (csq->strand==STRAND_REV ? "|-" : "|."), str); if ( csq->vstr.l ) kputs(csq->vstr.s, str); } void kprint_aa_prediction(args_t *args, int beg, kstring_t *aa, kstring_t *str) { if ( !args->brief_predictions || (int)aa->l - args->brief_predictions < 3 ) kputs(aa->s, str); else { int i, len = aa->l; if ( aa->s[len-1]=='*' ) len--; for (i=0; ibrief_predictions; i++) kputc(aa->s[i], str); kputs("..", str); kputw(beg+len, str); } } void hap_add_csq(args_t *args, hap_t *hap, hap_node_t *node, int tlen, int ibeg, int iend, int dlen, int indel) { int i; gf_tscript_t *tr = hap->tr; assert( tr->strand==STRAND_FWD || tr->strand==STRAND_REV ); int ref_node = tr->strand==STRAND_FWD ? ibeg : iend; int icsq = node->ncsq_list++; hts_expand0(csq_t,node->ncsq_list,node->mcsq_list,node->csq_list); csq_t *csq = &node->csq_list[icsq]; csq->pos = hap->stack[ref_node].node->rec->pos; csq->type.trid = tr->id; csq->type.vcf_ial = node->vcf_ial; csq->type.gene = tr->gene->name; csq->type.strand = tr->strand; csq->type.biotype = tr->type; // only now we see the translated sequence and can determine if the stop/start changes are real int rm_csq = 0; csq->type.type = 0; for (i=ibeg; i<=iend; i++) csq->type.type |= hap->stack[i].node->csq & CSQ_COMPOUND; if ( dlen==0 && indel ) csq->type.type |= CSQ_INFRAME_ALTERING; int has_upstream_stop = hap->upstream_stop; if ( hap->stack[ibeg].node->type != HAP_SSS ) { // check for truncating stops for (i=0; itref.l; i++) if ( hap->tref.s[i]=='*' ) break; if ( i!=hap->tref.l ) { hap->tref.l = i+1; hap->tref.s[i+1] = 0; } for (i=0; itseq.l; i++) if ( hap->tseq.s[i]=='*' ) break; if ( i!=hap->tseq.l ) { hap->tseq.l = i+1; hap->tseq.s[i+1] = 0; hap->upstream_stop = 1; } if ( csq->type.type & CSQ_STOP_LOST ) { if ( hap->tref.s[hap->tref.l-1]=='*' && hap->tref.s[hap->tref.l-1] == hap->tseq.s[hap->tseq.l-1] ) { rm_csq |= CSQ_STOP_LOST; csq->type.type |= CSQ_STOP_RETAINED; } else if ( hap->tref.s[hap->tref.l-1]!='*' ) { // This is CDS 3' incomplete ENSG00000173376/synon.vcf, can also be missense // We observe in real data a change to a stop, ENST00000528237/retained-stop-incomplete-cds.vcf if ( hap->tseq.s[hap->tseq.l-1] == '*' ) { rm_csq |= CSQ_STOP_GAINED; csq->type.type |= CSQ_STOP_RETAINED; } else csq->type.type |= CSQ_INCOMPLETE_CDS; } } if ( csq->type.type & CSQ_START_LOST && hap->tref.s[0]!='M' ) { rm_csq |= CSQ_START_LOST; csq->type.type &= ~CSQ_START_LOST; } if ( dlen!=0 ) { if ( dlen%3 ) csq->type.type |= CSQ_FRAMESHIFT_VARIANT; else if ( dlen<0 ) csq->type.type |= CSQ_INFRAME_DELETION; else csq->type.type |= CSQ_INFRAME_INSERTION; if ( hap->tref.s[hap->tref.l-1]!='*' && hap->tseq.s[hap->tseq.l-1]=='*' ) csq->type.type |= CSQ_STOP_GAINED; } else { int aa_change = 0; for (i=0; itref.l; i++) { if ( hap->tref.s[i] == hap->tseq.s[i] ) continue; aa_change = 1; if ( hap->tref.s[i] == '*' ) csq->type.type |= CSQ_STOP_LOST; else if ( hap->tseq.s[i] == '*' ) csq->type.type |= CSQ_STOP_GAINED; else csq->type.type |= CSQ_MISSENSE_VARIANT; } if ( !aa_change ) csq->type.type |= CSQ_SYNONYMOUS_VARIANT; } } // Check if compound inframe variants are real inframes, or if the stop codon occurs before the frameshift can be restored if ( ibeg!=iend && (csq->type.type & (CSQ_INFRAME_DELETION|CSQ_INFRAME_INSERTION|CSQ_INFRAME_ALTERING)) && hap->tseq.s[hap->tseq.l-1]=='*' ) { rm_csq |= CSQ_INFRAME_DELETION | CSQ_INFRAME_INSERTION | CSQ_INFRAME_ALTERING; csq->type.type |= CSQ_FRAMESHIFT_VARIANT | CSQ_STOP_GAINED; } if ( has_upstream_stop ) csq->type.type |= CSQ_UPSTREAM_STOP; csq->type.type &= ~rm_csq; if ( hap->stack[ibeg].node->type == HAP_SSS ) { node->csq_list[icsq].type.type |= hap->stack[ibeg].node->csq & ~rm_csq; node->csq_list[icsq].type.ref = hap->stack[ibeg].node->rec; node->csq_list[icsq].type.biotype = tr->type; csq_push(args, node->csq_list+icsq, hap->stack[ibeg].node->rec); return; } kstring_t str = node->csq_list[icsq].type.vstr; str.l = 0; // create the aa variant string int aa_rbeg = tr->strand==STRAND_FWD ? node2rbeg(ibeg)/3+1 : (TSCRIPT_AUX(hap->tr)->nsref - 2*N_REF_PAD - node2rend(iend))/3+1; int aa_sbeg = tr->strand==STRAND_FWD ? node2sbeg(ibeg)/3+1 : (tlen - node2send(iend))/3+1; kputc_('|', &str); kputw(aa_rbeg, &str); kprint_aa_prediction(args,aa_rbeg,&hap->tref,&str); if ( !(csq->type.type & CSQ_SYNONYMOUS_VARIANT) ) { kputc_('>', &str); kputw(aa_sbeg, &str); kprint_aa_prediction(args,aa_sbeg,&hap->tseq,&str); } kputc_('|', &str); // create the dna variant string and, in case of combined variants, // insert silent CSQ_PRINTED_UPSTREAM variants for (i=ibeg; i<=iend; i++) { if ( i>ibeg ) kputc_('+', &str); kputw(node2rpos(i)+1, &str); kputs(hap->stack[i].node->var, &str); } node->csq_list[icsq].type.vstr = str; csq_push(args, node->csq_list+icsq, hap->stack[ref_node].node->rec); for (i=ibeg; i<=iend; i++) { // csq are printed at one position only for combined variants, the rest is // silent and references the first if ( hap->stack[i].node->csq & ~CSQ_COMPOUND ) { node->ncsq_list++; hts_expand0(csq_t,node->ncsq_list,node->mcsq_list,node->csq_list); csq_t *tmp_csq = &node->csq_list[node->ncsq_list - 1]; tmp_csq->pos = hap->stack[i].node->rec->pos; tmp_csq->type.trid = tr->id; //??tmp_csq->type.vcf_ial = node->vcf_ial; .. this should not be needed for non-compound variants tmp_csq->type.gene = tr->gene->name; tmp_csq->type.strand = tr->strand; tmp_csq->type.type = hap->stack[i].node->csq & ~CSQ_COMPOUND & ~rm_csq; tmp_csq->type.biotype = tr->type; tmp_csq->type.vstr.l = 0; kputs(str.s,&tmp_csq->type.vstr); csq_push(args, tmp_csq, hap->stack[i].node->rec); } if ( i!=ref_node && (node->csq_list[icsq].type.type & CSQ_COMPOUND || !(hap->stack[i].node->csq & ~CSQ_COMPOUND)) ) { node->ncsq_list++; hts_expand0(csq_t,node->ncsq_list,node->mcsq_list,node->csq_list); csq_t *tmp_csq = &node->csq_list[node->ncsq_list - 1]; tmp_csq->pos = hap->stack[i].node->rec->pos; tmp_csq->type.trid = tr->id; //??tmp_csq->type.vcf_ial = node->vcf_ial; .. this should not be needed for non-compound variants tmp_csq->type.gene = tr->gene->name; tmp_csq->type.strand = tr->strand; tmp_csq->type.type = CSQ_PRINTED_UPSTREAM | hap->stack[i].node->csq; tmp_csq->type.biotype = tr->type; tmp_csq->type.ref = hap->stack[ref_node].node->rec; tmp_csq->type.vstr.l = 0; csq_push(args, tmp_csq, hap->stack[i].node->rec); } } } void hap_finalize(args_t *args, hap_t *hap) { gf_tscript_t *tr = hap->tr; if ( !TSCRIPT_AUX(tr)->sref ) tscript_splice_ref(tr); kstring_t sref; sref.s = TSCRIPT_AUX(tr)->sref; sref.l = TSCRIPT_AUX(tr)->nsref; sref.m = sref.l; int istack = 0; hts_expand(hstack_t,1,hap->mstack,hap->stack); hap->sseq.l = 0; hap->tseq.l = 0; hap->stack[0].node = TSCRIPT_AUX(tr)->root; hap->stack[0].ichild = -1; hap->stack[0].slen = 0; hap->stack[0].dlen = 0; while ( istack>=0 ) { hstack_t *stack = &hap->stack[istack]; hap_node_t *node = hap->stack[istack].node; while ( ++hap->stack[istack].ichild < node->nchild ) { if ( node->child[stack->ichild] ) break; } if ( stack->ichild == node->nchild ) { istack--; continue; } node = node->child[stack->ichild]; istack++; hts_expand(hstack_t,istack+1,hap->mstack,hap->stack); stack = &hap->stack[istack-1]; hap->stack[istack].node = node; hap->stack[istack].ichild = -1; hap->sseq.l = stack->slen; if ( node->type==HAP_CDS ) kputs(node->seq, &hap->sseq); hap->stack[istack].slen = hap->sseq.l; hap->stack[istack].dlen = hap->stack[istack-1].dlen + node->dlen; if ( !node->nend ) continue; // not a leaf node // The spliced sequence has been built for the current haplotype and stored // in hap->sseq. Now we break it and output as independent parts kstring_t sseq; sseq.m = sref.m - 2*N_REF_PAD + hap->stack[istack].dlen; // total length of the spliced query transcript hap->upstream_stop = 0; int i = 1, dlen = 0, ibeg, indel = 0; hap->sbeg = hap->stack[i].node->sbeg; assert( hap->stack[istack].node->type != HAP_SSS ); if ( tr->strand==STRAND_FWD ) { i = 0, ibeg = -1; while ( ++i <= istack ) { assert( hap->stack[i].node->type != HAP_SSS ); dlen += hap->stack[i].node->dlen; if ( hap->stack[i].node->dlen ) indel = 1; // This condition extends compound variants. if ( istack[i].node->dlen > 0 ) icur += hap->stack[i].node->dlen; else if ( hap->stack[i].node->dlen < 0 ) icur++; if ( icur/3 == inext/3 ) // in the same codon, can't be flushed yet { if ( ibeg==-1 ) ibeg = i; continue; } } if ( ibeg<0 ) ibeg = i; int ioff = node2soff(ibeg); int icur = node2sbeg(ibeg); int rbeg = node2rbeg(ibeg); int rend = node2rend(i); int fill = dlen%3; // alt if ( hap->sseq.l ) { sseq.l = hap->stack[i].slen - ioff; sseq.s = hap->sseq.s + ioff; } else // splice site overlap, see #1475227917 sseq.l = fill = 0; cds_translate(&sref, &sseq, icur,rbeg,rend, tr->strand, &hap->tseq, fill); // ref sseq.l = node2rend(i) - rbeg; sseq.s = sref.s + N_REF_PAD + rbeg; sseq.m = sref.m - 2*N_REF_PAD; cds_translate(&sref, &sseq, rbeg,rbeg,rend, tr->strand, &hap->tref, fill); sseq.m = sref.m - 2*N_REF_PAD + hap->stack[istack].dlen; hap_add_csq(args,hap,node,0, ibeg,i,dlen,indel); ibeg = -1; dlen = 0; indel = 0; } } else if ( tr->strand==STRAND_REV ) { i = istack + 1, ibeg = -1; while ( --i > 0 ) { assert ( hap->stack[i].node->type != HAP_SSS ); dlen += hap->stack[i].node->dlen; if ( hap->stack[i].node->dlen ) indel = 1; if ( i>1 ) { if ( dlen%3 ) { if ( ibeg==-1 ) ibeg = i; continue; } // the last base of the current variant vs the first base of the next // variant: are they in the same codon? (reverse strand) int icur = sseq.m - 1 - node2sbeg(i); int inext = sseq.m - 1 - node2sbeg(i-1); if ( hap->stack[i].node->dlen > 0 ) icur += hap->stack[i].node->dlen - 1; else if ( hap->stack[i].node->dlen < 0 ) icur -= hap->stack[i].node->dlen; if ( hap->stack[i-1].node->dlen > 0 ) inext -= hap->stack[i-1].node->dlen; if ( icur/3 == inext/3 ) { if ( ibeg==-1 ) ibeg = i; continue; } } if ( ibeg<0 ) ibeg = i; int ioff = node2soff(i); int icur = node2sbeg(i); int rbeg = node2rbeg(i); int rend = node2rend(ibeg); int fill = dlen%3; // alt if ( hap->sseq.l ) { sseq.l = hap->stack[ibeg].slen - ioff; sseq.s = hap->sseq.s + ioff; } else // splice site overlap, see #1475227917 sseq.l = fill = 0; cds_translate(&sref, &sseq, icur,rbeg,rend, tr->strand, &hap->tseq, fill); // ref sseq.l = node2rend(ibeg) - rbeg; sseq.s = sref.s + N_REF_PAD + rbeg; sseq.m = sref.m - 2*N_REF_PAD; cds_translate(&sref, &sseq, rbeg,rbeg,rend, tr->strand, &hap->tref, fill); sseq.m = sref.m - 2*N_REF_PAD + hap->stack[istack].dlen; hap_add_csq(args,hap,node,sseq.m, i,ibeg,dlen,indel); ibeg = -1; dlen = 0; indel = 0; } } } } static inline void csq_print_text(args_t *args, csq_t *csq, int ismpl, int ihap) { if ( csq->type.type & CSQ_PRINTED_UPSTREAM ) return; char *smpl = ismpl >= 0 ? args->hdr->samples[ismpl] : "-"; const char *chr = bcf_hdr_id2name(args->hdr,args->rid); fprintf(args->out,"CSQ\t%s\t", smpl); if ( ihap>0 ) fprintf(args->out,"%d", ihap); else fprintf(args->out,"-"); args->str.l = 0; kput_vcsq(args, &csq->type, &args->str); fprintf(args->out,"\t%s\t%d\t%s\n",chr,csq->pos+1,args->str.s); } static inline void hap_print_text(args_t *args, gf_tscript_t *tr, int ismpl, int ihap, hap_node_t *node) { if ( !node || !node->ncsq_list ) return; char *smpl = ismpl >= 0 ? args->hdr->samples[ismpl] : "-"; const char *chr = bcf_hdr_id2name(args->hdr,args->rid); int i; for (i=0; incsq_list; i++) { csq_t *csq = node->csq_list + i; if ( csq->type.type & CSQ_PRINTED_UPSTREAM ) continue; assert( csq->type.vstr.l ); fprintf(args->out,"CSQ\t%s\t", smpl); if ( ihap>0 ) fprintf(args->out,"%d", ihap); else fprintf(args->out,"-"); args->str.l = 0; kput_vcsq(args, &csq->type, &args->str); fprintf(args->out,"\t%s\t%d\t%s\n",chr,csq->pos+1,args->str.s); } } static inline void hap_stage_vcf(args_t *args, gf_tscript_t *tr, int ismpl, int ihap, hap_node_t *node) { if ( !node || !node->ncsq_list || ismpl<0 ) return; int i; for (i=0; incsq_list; i++) { csq_t *csq = node->csq_list + i; vrec_t *vrec = csq->vrec; int icsq2 = 2*csq->idx + ihap; if ( icsq2 >= args->ncsq2_max ) // more than ncsq2_max consequences, so can't fit it in FMT { if ( args->verbosity && (!args->ncsq2_small_warned || args->verbosity > 1) ) { fprintf(stderr, "Warning: Too many consequences for sample %s at %s:%"PRId64", keeping the first %d and skipping the rest.\n", args->hdr->samples[ismpl],bcf_hdr_id2name(args->hdr,args->rid),(int64_t) vrec->line->pos+1,csq->idx); if ( !args->ncsq2_small_warned ) fprintf(stderr," The limit can be increased by setting the --ncsq parameter. This warning is printed only once.\n"); } if ( args->ncsq2_small_warned < icsq2 ) args->ncsq2_small_warned = icsq2; break; } int ival, ibit; icsq2_to_bit(icsq2, &ival,&ibit); if ( vrec->nfmt < 1 + ival ) vrec->nfmt = 1 + ival; vrec->fmt_bm[ismpl*args->nfmt_bcsq + ival] |= 1 << ibit; } } void hap_flush(args_t *args, uint32_t pos) { int i,j; tr_heap_t *heap = args->active_tr; while ( heap->ndat && heap->dat[0]->end<=pos ) { gf_tscript_t *tr = heap->dat[0]; khp_delete(trhp, heap); args->hap->tr = tr; if ( TSCRIPT_AUX(tr)->root && TSCRIPT_AUX(tr)->root->nchild ) // normal, non-localized calling { hap_finalize(args, args->hap); if ( args->output_type==FT_TAB_TEXT ) // plain text output, not a vcf { if ( args->phase==PHASE_DROP_GT ) hap_print_text(args, tr, -1,0, TSCRIPT_AUX(tr)->hap[0]); else { for (i=0; ismpl->n; i++) { for (j=0; j<2; j++) hap_print_text(args, tr, args->smpl->idx[i],j+1, TSCRIPT_AUX(tr)->hap[i*2+j]); } } } else if ( args->phase!=PHASE_DROP_GT ) { for (i=0; ismpl->n; i++) { for (j=0; j<2; j++) hap_stage_vcf(args, tr, args->smpl->idx[i],j, TSCRIPT_AUX(tr)->hap[i*2+j]); } } } // mark the transcript for deletion. Cannot delete it immediately because // by-position VCF output will need them when flushed by vcf_buf_push args->nrm_tr++; hts_expand(gf_tscript_t*,args->nrm_tr,args->mrm_tr,args->rm_tr); args->rm_tr[args->nrm_tr-1] = tr; } } #define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } vbuf_t *vbuf_push(args_t *args, bcf1_t **rec_ptr) { int i; assert(rec_ptr); bcf1_t *rec = *rec_ptr; // check for duplicate records i = args->vcf_rbuf.n ? rbuf_last(&args->vcf_rbuf) : -1; if ( i<0 || args->vcf_buf[i]->vrec[0]->line->pos!=rec->pos ) { // vcf record with a new pos rbuf_expand0(&args->vcf_rbuf, vbuf_t*, args->vcf_rbuf.n+1, args->vcf_buf); i = rbuf_append(&args->vcf_rbuf); if ( !args->vcf_buf[i] ) args->vcf_buf[i] = (vbuf_t*) calloc(1,sizeof(vbuf_t)); args->vcf_buf[i]->n = 0; args->vcf_buf[i]->keep_until = 0; } vbuf_t *vbuf = args->vcf_buf[i]; vbuf->n++; hts_expand0(vrec_t*, vbuf->n, vbuf->m, vbuf->vrec); if ( !vbuf->vrec[vbuf->n - 1] ) vbuf->vrec[vbuf->n - 1] = (vrec_t*) calloc(1,sizeof(vrec_t)); vrec_t *vrec = vbuf->vrec[vbuf->n - 1]; if ( args->phase!=PHASE_DROP_GT && args->smpl->n ) { if ( !vrec->fmt_bm ) vrec->fmt_bm = (uint32_t*) calloc(args->hdr_nsmpl,sizeof(*vrec->fmt_bm) * args->nfmt_bcsq); else memset(vrec->fmt_bm,0,args->hdr_nsmpl*sizeof(*vrec->fmt_bm) * args->nfmt_bcsq); } if ( !vrec->line ) vrec->line = bcf_init1(); SWAP(bcf1_t*, (*rec_ptr), vrec->line); int ret; khint_t k = kh_put(pos2vbuf, args->pos2vbuf, (int)rec->pos, &ret); kh_val(args->pos2vbuf,k) = vbuf; return vbuf; } void vbuf_flush(args_t *args, uint32_t pos) { int i,j; while ( args->vcf_rbuf.n ) { vbuf_t *vbuf; if ( !args->local_csq && args->active_tr->ndat ) { // check if the first active transcript starts beyond the first buffered VCF record, // cannot output buffered VCF lines (args.vbuf) until the active transcripts are gone vbuf = args->vcf_buf[ args->vcf_rbuf.f ]; if ( vbuf->keep_until > pos ) break; assert( vbuf->n ); } i = rbuf_shift(&args->vcf_rbuf); assert( i>=0 ); vbuf = args->vcf_buf[i]; int pos = vbuf->n ? vbuf->vrec[0]->line->pos : -1; for (i=0; in; i++) { vrec_t *vrec = vbuf->vrec[i]; if ( !args->out_fh ) // not a VCF output { vrec->nvcsq = 0; continue; } if ( !vrec->nvcsq ) { if ( bcf_write(args->out_fh, args->hdr, vrec->line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname?args->output_fname:"standard output"); int save_pos = vrec->line->pos; bcf_empty(vrec->line); vrec->line->pos = save_pos; // this is necessary for compound variants continue; } args->str.l = 0; kput_vcsq(args, &vrec->vcsq[0], &args->str); for (j=1; jnvcsq; j++) { kputc_(',', &args->str); kput_vcsq(args, &vrec->vcsq[j], &args->str); } bcf_update_info_string(args->hdr, vrec->line, args->bcsq_tag, args->str.s); if ( args->hdr_nsmpl ) { if ( vrec->nfmt < args->nfmt_bcsq ) for (j=1; jhdr_nsmpl; j++) memmove(&vrec->fmt_bm[j*vrec->nfmt], &vrec->fmt_bm[j*args->nfmt_bcsq], vrec->nfmt*sizeof(*vrec->fmt_bm)); bcf_update_format_int32(args->hdr, vrec->line, args->bcsq_tag, vrec->fmt_bm, args->hdr_nsmpl*vrec->nfmt); } vrec->nvcsq = 0; if ( bcf_write(args->out_fh, args->hdr, vrec->line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname?args->output_fname:"standard output"); int save_pos = vrec->line->pos; bcf_empty(vrec->line); vrec->line->pos = save_pos; } if ( pos!=-1 ) { khint_t k = kh_get(pos2vbuf, args->pos2vbuf, pos); if ( k != kh_end(args->pos2vbuf) ) kh_del(pos2vbuf, args->pos2vbuf, k); } vbuf->n = 0; } if ( args->active_tr->ndat ) return; for (i=0; inrm_tr; i++) { gf_tscript_t *tr = args->rm_tr[i]; tscript_t *aux = TSCRIPT_AUX(tr); if ( aux->root ) hap_destroy(aux->root); aux->root = NULL; free(aux->hap); free(aux->ref); free(aux->sref); free(aux); tr->aux = NULL; } args->nrm_tr = 0; args->ncsq_buf = 0; } void tscript_init_ref(args_t *args, gf_tscript_t *tr, const char *chr) { int i, len; int pad_beg = tr->beg >= N_REF_PAD ? N_REF_PAD : tr->beg; const char *tmp_chr = chr; if ( !faidx_has_seq(args->fai,tmp_chr) ) { tmp_chr = drop_chr_prefix(args,chr); if ( !faidx_has_seq(args->fai,tmp_chr) ) tmp_chr = add_chr_prefix(args,chr); } TSCRIPT_AUX(tr)->ref = faidx_fetch_seq(args->fai, tmp_chr, tr->beg - pad_beg, tr->end + N_REF_PAD, &len); if ( !TSCRIPT_AUX(tr)->ref ) error("faidx_fetch_seq failed %s:%d-%d\n", chr,tr->beg+1,tr->end+1); int pad_end = len - (tr->end - tr->beg + 1 + pad_beg); if ( pad_beg + pad_end != 2*N_REF_PAD ) { char *ref = (char*) malloc(tr->end - tr->beg + 1 + 2*N_REF_PAD + 1); for (i=0; i < N_REF_PAD - pad_beg; i++) ref[i] = 'N'; memcpy(ref+i, TSCRIPT_AUX(tr)->ref, len); len += i; for (i=0; i < N_REF_PAD - pad_end; i++) ref[i+len] = 'N'; ref[i+len] = 0; free(TSCRIPT_AUX(tr)->ref); TSCRIPT_AUX(tr)->ref = ref; } } static void sanity_check_ref(args_t *args, gf_tscript_t *tr, bcf1_t *rec) { int vbeg = 0; int rbeg = rec->pos - tr->beg + N_REF_PAD; if ( rbeg < 0 ) { vbeg += abs(rbeg); rbeg = 0; } char *ref = TSCRIPT_AUX(tr)->ref + rbeg; char *vcf = rec->d.allele[0] + vbeg; assert( vcf - rec->d.allele[0] < strlen(rec->d.allele[0]) && ref - TSCRIPT_AUX(tr)->ref < tr->end - tr->beg + 2*N_REF_PAD ); int i = 0; while ( ref[i] && vcf[i] ) { if ( ref[i]!=vcf[i] && toupper(ref[i])!=toupper(vcf[i]) ) error("Error: the fasta reference does not match the VCF REF allele at %s:%"PRId64" .. fasta=%c vcf=%c\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+vbeg+1,ref[i],vcf[i]); i++; } } int test_cds_local(args_t *args, bcf1_t *rec) { int i,j, ret = 0; const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,rec)); // note that the off-by-one extension of rlen is deliberate to account for insertions if ( !regidx_overlap(args->idx_cds,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; // structures to fake the normal test_cds machinery hap_node_t root, node; root.type = HAP_ROOT; kstring_t *tref = &args->hap->tref, *tseq = &args->hap->tseq; while ( regitr_overlap(args->itr) ) { gf_cds_t *cds = regitr_payload(args->itr,gf_cds_t*); gf_tscript_t *tr = cds->tr; if ( !GF_is_coding(tr->type) ) continue; ret = 1; if ( !TSCRIPT_AUX(tr) ) { tr->aux = calloc(sizeof(tscript_t),1); tscript_init_ref(args, tr, chr); tscript_splice_ref(tr); khp_insert(trhp, args->active_tr, &tr); // only to clean the reference afterwards } sanity_check_ref(args, tr, rec); kstring_t sref; sref.s = TSCRIPT_AUX(tr)->sref; sref.l = TSCRIPT_AUX(tr)->nsref; sref.m = sref.l; for (i=1; in_allele; i++) { if ( rec->d.allele[i][0]=='<' || rec->d.allele[i][0]=='*' ) { continue; } if ( hap_init(args, &root, &node, cds, rec, i)!=0 ) continue; csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.vcf_ial = i; csq.type.gene = tr->gene->name; int csq_type = node.csq; // code repetition: it would be nice to reuse the code from hap_add_csq, needs refactoring though if ( node.type == HAP_SSS ) { csq.type.type = csq_type; csq_stage(args, &csq, rec); } else { kstring_t sseq; sseq.m = sref.m - 2*N_REF_PAD + node.dlen; sseq.s = node.seq; int alen = sseq.l = strlen(sseq.s); int fill = node.dlen%3 && alen ? 1 : 0; // see #1475227917 cds_translate(&sref, &sseq, node.sbeg,node.sbeg,node.sbeg+node.rlen, tr->strand, tseq, fill); sseq.m = sref.m - 2*N_REF_PAD; sseq.s = sref.s + N_REF_PAD + node.sbeg; sseq.l = node.rlen; cds_translate(&sref, &sseq, node.sbeg,node.sbeg,node.sbeg+node.rlen, tr->strand, tref, fill); // check for truncating stops for (j=0; jl; j++) if ( tref->s[j]=='*' ) break; if ( j!=tref->l ) { tref->l = j+1; tref->s[j+1] = 0; } for (j=0; jl; j++) if ( tseq->s[j]=='*' ) break; if ( j!=tseq->l ) { tseq->l = j+1; tseq->s[j+1] = 0; } if ( csq_type & CSQ_STOP_LOST ) { if ( tref->s[tref->l-1]=='*' && tref->s[tref->l-1] == tseq->s[tseq->l-1] ) { csq_type &= ~CSQ_STOP_LOST; csq_type |= CSQ_STOP_RETAINED; } else if (tref->s[tref->l-1]!='*' ) { // This is CDS 3' incomplete ENSG00000173376/synon.vcf, can also be missense // We observe in real data a change to a stop, ENST00000528237/retained-stop-incomplete-cds.vcf if ( tseq->s[tseq->l-1] == '*' ) { csq_type &= ~CSQ_STOP_GAINED; csq_type |= CSQ_STOP_RETAINED; } else csq_type |= CSQ_INCOMPLETE_CDS; } } if ( csq_type & CSQ_START_LOST && tref->s[0]!='M' ) csq_type &= ~CSQ_START_LOST; if ( node.dlen!=0 ) { if ( node.dlen%3 ) csq_type |= CSQ_FRAMESHIFT_VARIANT; else if ( node.dlen<0 ) csq_type |= CSQ_INFRAME_DELETION; else csq_type |= CSQ_INFRAME_INSERTION; if ( tref->s[tref->l-1]!='*' && tseq->s[tseq->l-1]=='*' ) csq_type |= CSQ_STOP_GAINED; } else { int aa_change = 0; for (j=0; jl; j++) { if ( tref->s[j] == tseq->s[j] ) continue; aa_change = 1; if ( tref->s[j] == '*' ) csq_type |= CSQ_STOP_LOST; else if ( tseq->s[j] == '*' ) csq_type |= CSQ_STOP_GAINED; else csq_type |= CSQ_MISSENSE_VARIANT; } if ( !aa_change ) csq_type |= CSQ_SYNONYMOUS_VARIANT; } if ( csq_type & CSQ_COMPOUND ) { // create the aa variant string kstring_t str = {0,0,0}; int aa_rbeg = tr->strand==STRAND_FWD ? node.sbeg/3+1 : (TSCRIPT_AUX(tr)->nsref - 2*N_REF_PAD - node.sbeg - node.rlen)/3+1; int aa_sbeg = tr->strand==STRAND_FWD ? node.sbeg/3+1 : (TSCRIPT_AUX(tr)->nsref - 2*N_REF_PAD + node.dlen - node.sbeg - alen)/3+1; kputc_('|', &str); kputw(aa_rbeg, &str); kprint_aa_prediction(args,aa_rbeg,tref,&str); if ( !(csq_type & CSQ_SYNONYMOUS_VARIANT) ) { kputc_('>', &str); kputw(aa_sbeg, &str); kprint_aa_prediction(args,aa_sbeg,tseq,&str); } kputc_('|', &str); kputw(rec->pos+1, &str); kputs(node.var, &str); csq.type.vstr = str; csq.type.type = csq_type & CSQ_COMPOUND; csq_stage(args, &csq, rec); // all this only to clean vstr when vrec is flushed if ( !TSCRIPT_AUX(tr)->root ) TSCRIPT_AUX(tr)->root = (hap_node_t*) calloc(1,sizeof(hap_node_t)); TSCRIPT_AUX(tr)->root->ncsq_list++; hts_expand0(csq_t,TSCRIPT_AUX(tr)->root->ncsq_list,TSCRIPT_AUX(tr)->root->mcsq_list,TSCRIPT_AUX(tr)->root->csq_list); csq_t *rm_csq = TSCRIPT_AUX(tr)->root->csq_list + TSCRIPT_AUX(tr)->root->ncsq_list - 1; rm_csq->type.vstr = str; } if ( csq_type & ~CSQ_COMPOUND ) { csq.type.type = csq_type & ~CSQ_COMPOUND; csq.type.vstr.l = 0; csq_stage(args, &csq, rec); } } free(node.seq); free(node.var); } } return ret; } int test_cds(args_t *args, bcf1_t *rec, vbuf_t *vbuf) { static int overlaps_warned = 0, multiploid_warned = 0; int i, ret = 0, hap_ret; const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,rec)); // note that the off-by-one extension of rlen is deliberate to account for insertions if ( !regidx_overlap(args->idx_cds,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; while ( regitr_overlap(args->itr) ) { gf_cds_t *cds = regitr_payload(args->itr,gf_cds_t*); gf_tscript_t *tr = cds->tr; if ( !GF_is_coding(tr->type) ) continue; if ( vbuf->keep_until < tr->end ) vbuf->keep_until = tr->end; ret = 1; if ( !TSCRIPT_AUX(tr) ) { // initialize the transcript and its haplotype tree, fetch the reference sequence tr->aux = calloc(sizeof(tscript_t),1); tscript_init_ref(args, tr, chr); TSCRIPT_AUX(tr)->root = (hap_node_t*) calloc(1,sizeof(hap_node_t)); TSCRIPT_AUX(tr)->nhap = args->phase==PHASE_DROP_GT ? 1 : 2*args->smpl->n; // maximum ploidy = diploid TSCRIPT_AUX(tr)->hap = (hap_node_t**) malloc(TSCRIPT_AUX(tr)->nhap*sizeof(hap_node_t*)); for (i=0; inhap; i++) TSCRIPT_AUX(tr)->hap[i] = NULL; TSCRIPT_AUX(tr)->root->nend = TSCRIPT_AUX(tr)->nhap; TSCRIPT_AUX(tr)->root->type = HAP_ROOT; khp_insert(trhp, args->active_tr, &tr); } sanity_check_ref(args, tr, rec); if ( args->phase==PHASE_DROP_GT ) { if ( rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*' ) { continue; } hap_node_t *parent = TSCRIPT_AUX(tr)->hap[0] ? TSCRIPT_AUX(tr)->hap[0] : TSCRIPT_AUX(tr)->root; hap_node_t *child = (hap_node_t*)calloc(1,sizeof(hap_node_t)); hap_ret = hap_init(args, parent, child, cds, rec, 1); if ( hap_ret!=0 ) { // overlapping or intron variant, cannot apply if ( hap_ret==1 ) { if ( args->verbosity && (!overlaps_warned || args->verbosity > 1) ) { fprintf(stderr, "Warning: Skipping overlapping variants at %s:%"PRId64"\t%s>%s.\n", chr,(int64_t) rec->pos+1,rec->d.allele[0],rec->d.allele[1]); if ( !overlaps_warned ) fprintf(stderr," This message is printed only once, the verbosity can be increased with `--verbose 2`\n"); overlaps_warned = 1; } if ( args->out ) fprintf(args->out,"LOG\tWarning: Skipping overlapping variants at %s:%"PRId64"\t%s>%s\n", chr,(int64_t) rec->pos+1,rec->d.allele[0],rec->d.allele[1]); } else ret = 1; // prevent reporting as intron in test_tscript hap_destroy(child); continue; } if ( child->type==HAP_SSS ) { csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.vcf_ial = 1; csq.type.gene = tr->gene->name; csq.type.type = child->csq; csq_stage(args, &csq, rec); hap_destroy(child); ret = 1; continue; } parent->nend--; parent->nchild = 1; parent->mchild = 1; parent->child = (hap_node_t**) malloc(sizeof(hap_node_t*)); parent->child[0] = child; TSCRIPT_AUX(tr)->hap[0] = child; TSCRIPT_AUX(tr)->hap[0]->nend = 1; continue; } // apply the VCF variants and extend the haplotype tree int j, ismpl, ihap, ngts = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); ngts /= bcf_hdr_nsamples(args->hdr); if ( ngts!=1 && ngts!=2 ) { if ( args->verbosity && (!multiploid_warned || args->verbosity > 1) ) { fprintf(stderr, "Warning: Skipping site with non-diploid/non-haploid genotypes at %s:%"PRId64"\t%s>%s.\n", chr,(int64_t) rec->pos+1,rec->d.allele[0],rec->d.allele[1]); if ( !multiploid_warned ) fprintf(stderr," This message is printed only once, the verbosity can be increased with `--verbose 2`\n"); multiploid_warned = 1; } if ( args->out ) fprintf(args->out,"LOG\tWarning: Skipping site with non-diploid/non-haploid genotypes at %s:%"PRId64"\t%s>%s\n", chr,(int64_t) rec->pos+1,rec->d.allele[0],rec->d.allele[1]); continue; } for (ismpl=0; ismplsmpl->n; ismpl++) { int32_t *gt = args->gt_arr + args->smpl->idx[ismpl]*ngts; if ( gt[0]==bcf_gt_missing ) continue; if ( ngts>1 && gt[1]!=bcf_gt_missing && gt[1]!=bcf_int32_vector_end && bcf_gt_allele(gt[0])!=bcf_gt_allele(gt[1]) ) { if ( args->phase==PHASE_MERGE ) { if ( !bcf_gt_allele(gt[0]) ) gt[0] = gt[1]; } if ( !bcf_gt_is_phased(gt[0]) && !bcf_gt_is_phased(gt[1]) ) { if ( args->phase==PHASE_REQUIRE ) error("Unphased heterozygous genotype at %s:%"PRId64", sample %s. See the --phase option.\n", chr,(int64_t) rec->pos+1,args->hdr->samples[args->smpl->idx[ismpl]]); if ( args->phase==PHASE_SKIP ) continue; if ( args->phase==PHASE_NON_REF ) { if ( !bcf_gt_allele(gt[0]) ) gt[0] = gt[1]; else if ( !bcf_gt_allele(gt[1]) ) gt[1] = gt[0]; } } } for (ihap=0; ihapn_allele ); if ( rec->d.allele[ial][0]=='<' || rec->d.allele[ial][0]=='*' ) { continue; } hap_node_t *parent = TSCRIPT_AUX(tr)->hap[i] ? TSCRIPT_AUX(tr)->hap[i] : TSCRIPT_AUX(tr)->root; if ( parent->cur_rec==rec && parent->cur_child[ial]>=0 ) { // this haplotype has been seen in another sample TSCRIPT_AUX(tr)->hap[i] = parent->child[ parent->cur_child[ial] ]; TSCRIPT_AUX(tr)->hap[i]->nend++; parent->nend--; continue; } hap_node_t *child = (hap_node_t*)calloc(1,sizeof(hap_node_t)); hap_ret = hap_init(args, parent, child, cds, rec, ial); if ( hap_ret!=0 ) { // overlapping or intron variant, cannot apply if ( hap_ret==1 ) { if ( args->verbosity && (!overlaps_warned || args->verbosity > 1) ) { fprintf(stderr, "Warning: Skipping overlapping variants at %s:%"PRId64", sample %s\t%s>%s.\n", chr,(int64_t) rec->pos+1,args->hdr->samples[args->smpl->idx[ismpl]],rec->d.allele[0],rec->d.allele[ial]); if ( !overlaps_warned ) fprintf(stderr," This message is printed only once, the verbosity can be increased with `--verbose 2`\n"); overlaps_warned = 1; } if ( args->out ) fprintf(args->out,"LOG\tWarning: Skipping overlapping variants at %s:%"PRId64", sample %s\t%s>%s\n", chr,(int64_t) rec->pos+1,args->hdr->samples[args->smpl->idx[ismpl]],rec->d.allele[0],rec->d.allele[ial]); } hap_destroy(child); continue; } if ( child->type==HAP_SSS ) { csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.vcf_ial = ial; csq.type.gene = tr->gene->name; csq.type.type = child->csq; csq_stage(args, &csq, rec); hap_destroy(child); continue; } if ( parent->cur_rec!=rec ) { hts_expand(int,rec->n_allele,parent->mcur_child,parent->cur_child); for (j=0; jn_allele; j++) parent->cur_child[j] = -1; parent->cur_rec = rec; } j = parent->nchild++; hts_expand0(hap_node_t*,parent->nchild,parent->mchild,parent->child); parent->cur_child[ial] = j; parent->child[j] = child; TSCRIPT_AUX(tr)->hap[i] = child; TSCRIPT_AUX(tr)->hap[i]->nend++; parent->nend--; } } } return ret; } void csq_stage(args_t *args, csq_t *csq, bcf1_t *rec) { // known issues: tab output leads to unsorted output. This is because // coding haplotypes are printed in one go and buffering is not used // with tab output. VCF output is OK though. if ( csq_push(args, csq, rec)!=0 && args->phase==PHASE_DROP_GT ) return; // the consequence already exists int i,j,ngt = 0; if ( args->phase!=PHASE_DROP_GT ) { ngt = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); if ( ngt>0 ) ngt /= bcf_hdr_nsamples(args->hdr); } if ( ngt<=0 ) { if ( args->output_type==FT_TAB_TEXT ) csq_print_text(args, csq, -1,0); return; } assert( ngt<=2 ); if ( args->output_type==FT_TAB_TEXT ) { for (i=0; ismpl->n; i++) { int32_t *gt = args->gt_arr + args->smpl->idx[i]*ngt; for (j=0; jtype.vcf_ial ) continue; csq_print_text(args, csq, args->smpl->idx[i],j+1); } } return; } vrec_t *vrec = csq->vrec; for (i=0; ismpl->n; i++) { int32_t *gt = args->gt_arr + args->smpl->idx[i]*ngt; for (j=0; jtype.vcf_ial ) continue; int icsq2 = 2*csq->idx + j; if ( icsq2 >= args->ncsq2_max ) // more than ncsq_max consequences, so can't fit it in FMT { int ismpl = args->smpl->idx[i]; if ( args->verbosity && (!args->ncsq2_small_warned || args->verbosity > 1) ) { fprintf(stderr, "Warning: Too many consequences for sample %s at %s:%"PRId64", keeping the first %d and skipping the rest.\n", args->hdr->samples[ismpl],bcf_hdr_id2name(args->hdr,args->rid),(int64_t) vrec->line->pos+1,icsq2+1); if ( !args->ncsq2_small_warned ) fprintf(stderr," The limit can be increased by setting the --ncsq parameter. This warning is printed only once.\n"); args->ncsq2_small_warned = 1; } if ( args->ncsq2_small_warned < icsq2 ) args->ncsq2_small_warned = icsq2; break; } int ival, ibit; icsq2_to_bit(icsq2, &ival,&ibit); if ( vrec->nfmt < 1 + ival ) vrec->nfmt = 1 + ival; vrec->fmt_bm[i*args->nfmt_bcsq + ival] |= 1 << ibit; } } } int test_utr(args_t *args, bcf1_t *rec) { const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,rec)); // note that the off-by-one extension of rlen is deliberate to account for insertions if ( !regidx_overlap(args->idx_utr,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; splice_t splice; splice_init(&splice, rec); int i, ret = 0; while ( regitr_overlap(args->itr) ) { gf_utr_t *utr = regitr_payload(args->itr, gf_utr_t*); gf_tscript_t *tr = splice.tr = utr->tr; for (i=1; in_allele; i++) { if ( rec->d.allele[i][0]=='<' || rec->d.allele[i][0]=='*' ) { continue; } splice.vcf.alt = rec->d.allele[i]; splice.csq = 0; int splice_ret = splice_csq(args, &splice, utr->beg, utr->end); if ( splice_ret!=SPLICE_INSIDE && splice_ret!=SPLICE_OVERLAP ) continue; csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.type = utr->which==prime5 ? CSQ_UTR5 : CSQ_UTR3; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.vcf_ial = i; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); ret = 1; } } assert(!splice.kref.s); assert(!splice.kalt.s); return ret; } int test_splice(args_t *args, bcf1_t *rec) { const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,rec)); if ( !regidx_overlap(args->idx_exon,chr,rec->pos,rec->pos + rec->rlen, args->itr) ) return 0; splice_t splice; splice_init(&splice, rec); splice.check_acceptor = splice.check_donor = 1; int i, ret = 0; while ( regitr_overlap(args->itr) ) { gf_exon_t *exon = regitr_payload(args->itr, gf_exon_t*); splice.tr = exon->tr; if ( !splice.tr->ncds ) continue; // not a coding transcript, no interest in splice sites splice.check_region_beg = splice.tr->beg==exon->beg ? 0 : 1; splice.check_region_end = splice.tr->end==exon->end ? 0 : 1; for (i=1; in_allele; i++) { if ( rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*' ) { continue; } splice.vcf.alt = rec->d.allele[i]; splice.csq = 0; splice_csq(args, &splice, exon->beg, exon->end); if ( splice.csq ) ret = 1; } } free(splice.kref.s); free(splice.kalt.s); return ret; } int test_tscript(args_t *args, bcf1_t *rec) { const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,rec)); if ( !regidx_overlap(args->idx_tscript,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; splice_t splice; splice_init(&splice, rec); int i, ret = 0; while ( regitr_overlap(args->itr) ) { gf_tscript_t *tr = splice.tr = regitr_payload(args->itr, gf_tscript_t*); for (i=1; in_allele; i++) { if ( rec->d.allele[i][0]=='<' || rec->d.allele[i][0]=='*' ) { continue; } splice.vcf.alt = rec->d.allele[i]; splice.csq = 0; int splice_ret = splice_csq(args, &splice, tr->beg, tr->end); if ( splice_ret!=SPLICE_INSIDE && splice_ret!=SPLICE_OVERLAP ) continue; // SPLICE_OUTSIDE or SPLICE_REF csq_t csq; memset(&csq, 0, sizeof(csq_t)); csq.pos = rec->pos; csq.type.type = GF_is_coding(tr->type) ? CSQ_INTRON : CSQ_NON_CODING; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); ret = 1; } } assert(!splice.kref.s); assert(!splice.kalt.s); return ret; } void test_symbolic_alt(args_t *args, bcf1_t *rec) { static int warned = 0; if ( args->verbosity && (!warned && args->verbosity > 0) ) { fprintf(stderr,"Warning: The support for symbolic ALT insertions is experimental.\n"); warned = 1; } const char *chr = drop_chr_prefix(args, bcf_seqname(args->hdr,rec)); // only insertions atm int beg = rec->pos + 1; int end = beg; int csq_class = CSQ_ELONGATION; int hit = 0; if ( regidx_overlap(args->idx_cds,chr,beg,end, args->itr) ) { while ( regitr_overlap(args->itr) ) { csq_t csq; memset(&csq, 0, sizeof(csq_t)); gf_cds_t *cds = regitr_payload(args->itr,gf_cds_t*); gf_tscript_t *tr = cds->tr; csq.type.type = (GF_is_coding(tr->type) ? CSQ_CODING_SEQUENCE : CSQ_NON_CODING) | csq_class; csq.pos = rec->pos; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); hit = 1; } } if ( regidx_overlap(args->idx_utr,chr,beg,end, args->itr) ) { while ( regitr_overlap(args->itr) ) { csq_t csq; memset(&csq, 0, sizeof(csq_t)); gf_utr_t *utr = regitr_payload(args->itr, gf_utr_t*); gf_tscript_t *tr = utr->tr; csq.type.type = (utr->which==prime5 ? CSQ_UTR5 : CSQ_UTR3) | csq_class; csq.pos = rec->pos; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); hit = 1; } } if ( regidx_overlap(args->idx_exon,chr,beg,end, args->itr) ) { splice_t splice; splice_init(&splice, rec); splice.check_acceptor = splice.check_donor = 1; while ( regitr_overlap(args->itr) ) { gf_exon_t *exon = regitr_payload(args->itr, gf_exon_t*); splice.tr = exon->tr; if ( !splice.tr->ncds ) continue; // not a coding transcript, no interest in splice sites splice.check_region_beg = splice.tr->beg==exon->beg ? 0 : 1; splice.check_region_end = splice.tr->end==exon->end ? 0 : 1; splice.vcf.alt = rec->d.allele[1]; splice.csq = csq_class; splice_csq(args, &splice, exon->beg, exon->end); if ( splice.csq ) hit = 1; } } if ( !hit && regidx_overlap(args->idx_tscript,chr,beg,end, args->itr) ) { splice_t splice; splice_init(&splice, rec); while ( regitr_overlap(args->itr) ) { csq_t csq; memset(&csq, 0, sizeof(csq_t)); gf_tscript_t *tr = splice.tr = regitr_payload(args->itr, gf_tscript_t*); splice.vcf.alt = rec->d.allele[1]; splice.csq = csq_class; int splice_ret = splice_csq(args, &splice, tr->beg, tr->end); if ( splice_ret!=SPLICE_INSIDE && splice_ret!=SPLICE_OVERLAP ) continue; // SPLICE_OUTSIDE or SPLICE_REF csq.type.type = (GF_is_coding(tr->type) ? CSQ_INTRON : CSQ_NON_CODING) | csq_class; csq.pos = rec->pos; csq.type.biotype = tr->type; csq.type.strand = tr->strand; csq.type.trid = tr->id; csq.type.gene = tr->gene->name; csq_stage(args, &csq, rec); } } } void debug_print_buffers(args_t *args, int pos) { int i,j; fprintf(stderr,"debug_print_buffers at %d\n", pos); fprintf(stderr,"vbufs:\n"); for (i=0; ivcf_rbuf.n; i++) { int k = rbuf_kth(&args->vcf_rbuf, i); vbuf_t *vbuf = args->vcf_buf[k]; fprintf(stderr,"\tvbuf %d:\n", i); for (j=0; jn; j++) { vrec_t *vrec = vbuf->vrec[j]; fprintf(stderr,"\t\t%"PRId64" .. nvcsq=%d\n", (int64_t) vrec->line->pos+1, vrec->nvcsq); } } fprintf(stderr,"pos2vbuf:"); khint_t k; for (k = 0; k < kh_end(args->pos2vbuf); ++k) if (kh_exist(args->pos2vbuf, k)) fprintf(stderr," %d",1+(int)kh_key(args->pos2vbuf, k)); fprintf(stderr,"\n"); fprintf(stderr,"active_tr: %d\n", args->active_tr->ndat); } static void process(args_t *args, bcf1_t **rec_ptr) { if ( !rec_ptr ) { hap_flush(args, REGIDX_MAX); vbuf_flush(args, REGIDX_MAX); return; } bcf1_t *rec = *rec_ptr; static int32_t prev_rid = -1, prev_pos = -1; if ( prev_rid!=rec->rid ) { prev_rid = rec->rid; prev_pos = rec->pos; // Common error is to use different naming conventions in the fasta and the VCF (e.g. X vs chrX). // Perform a simple sanity check (that does not catch much), the chromosome must be present in the // reference file if ( !faidx_has_seq(args->fai,bcf_seqname(args->hdr,rec)) ) { if ( !faidx_has_seq(args->fai,drop_chr_prefix(args,bcf_seqname(args->hdr,rec))) && !faidx_has_seq(args->fai,add_chr_prefix(args,bcf_seqname(args->hdr,rec))) ) error("Error: the chromosome \"%s\" is not present in %s\n",bcf_seqname(args->hdr,rec),args->fa_fname); } } if ( prev_pos > rec->pos ) error("Error: The file is not sorted, %s:%d comes before %s:%"PRId64"\n",bcf_seqname(args->hdr,rec),prev_pos+1,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); int call_csq = 1; if ( rec->n_allele < 2 ) call_csq = 0; // no alternate allele else if ( rec->n_allele==2 && (rec->d.allele[1][0]=='*' || rec->d.allele[1][1]=='*') ) call_csq = 0; // gVCF, not an alt allele else if ( rec->d.allele[1][0]=='<' ) { if ( strncmp("d.allele[1], 4) ) call_csq = 0; // only is supported at the moment } if ( call_csq && args->filter ) { call_csq = filter_test(args->filter, rec, NULL); if ( args->filter_logic==FLT_EXCLUDE ) call_csq = call_csq ? 0 : 1; } if ( !call_csq ) { if ( !args->out_fh ) return; // not a VCF output vbuf_push(args, rec_ptr); hap_flush(args, rec->pos-1); vbuf_flush(args, rec->pos-1); return; } if ( args->rid != rec->rid ) { hap_flush(args, REGIDX_MAX); vbuf_flush(args, REGIDX_MAX); } args->rid = rec->rid; vbuf_t *vbuf = vbuf_push(args, rec_ptr); if ( rec->d.allele[1][0]!='<' ) { int hit = args->local_csq ? test_cds_local(args, rec) : test_cds(args, rec, vbuf); hit += test_utr(args, rec); hit += test_splice(args, rec); if ( !hit ) test_tscript(args, rec); } else test_symbolic_alt(args, rec); if ( rec->pos > 0 ) { hap_flush(args, rec->pos-1); vbuf_flush(args, rec->pos-1); } return; } static const char *usage(void) { return "\n" "About: Haplotype-aware consequence caller.\n" "Usage: bcftools csq [OPTIONS] in.vcf\n" "\n" "Required options:\n" " -f, --fasta-ref FILE Reference file in fasta format\n" " -g, --gff-annot FILE GFF3 annotation file\n" "\n" "CSQ options:\n" " -B, --trim-protein-seq INT Abbreviate protein-changing predictions to max INT aminoacids\n" " -c, --custom-tag STRING Use this tag instead of the default BCSQ\n" " -l, --local-csq Localized predictions, consider only one VCF record at a time\n" " -n, --ncsq INT Maximum number of per-haplotype consequences to consider for each site [15]\n" " -p, --phase a|m|r|R|s How to handle unphased heterozygous genotypes: [r]\n" " a: take GTs as is, create haplotypes regardless of phase (0/1 -> 0|1)\n" " m: merge *all* GTs into a single haplotype (0/1 -> 1, 1/2 -> 1)\n" " r: require phased GTs, throw an error on unphased het GTs\n" " R: create non-reference haplotypes if possible (0/1 -> 1|1, 1/2 -> 1|2)\n" " s: skip unphased hets\n" "GFF options:\n" " --dump-gff FILE.gz Dump the parsed GFF file (for debugging purposes)\n" " --force Run even if some sanity checks fail\n" " --unify-chr-names 1|0 Automatically unify chromosome naming (e.g. chrX vs X) in GFF, fasta, and VCF [1]\n" "General options:\n" " -e, --exclude EXPR Exclude sites for which the expression is true\n" " -i, --include EXPR Select sites for which the expression is true\n" " --no-version Do not append version and command line to the header\n" " -o, --output FILE Write output to a file [standard output]\n" " -O, --output-type b|u|z|v|t[0-9] b: compressed BCF, u: uncompressed BCF, z: compressed VCF\n" " v: uncompressed VCF, t: plain tab-delimited text output, 0-9: compression level [v]\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -s, --samples -|LIST Samples to include or \"-\" to apply all variants and ignore samples\n" " -S, --samples-file FILE Samples to include\n" " -t, --targets REGION Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " --threads INT Use multithreading with worker threads [0]\n" " -v, --verbose INT Verbosity level 0-2 [1]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "Example:\n" " bcftools csq -f hs37d5.fa -g Homo_sapiens.GRCh37.87.gff3.gz in.vcf\n" "\n" " # GFF3 annotation files can be downloaded from Ensembl. e.g. for human:\n" " http://ftp.ensembl.org/pub/current_gff3/homo_sapiens/\n" " http://ftp.ensembl.org/pub/grch37/current/gff3/homo_sapiens/\n" "\n"; } int main_csq(int argc, char *argv[]) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->bcsq_tag = "BCSQ"; args->ncsq2_max = 2*(16-1); // 1 bit is reserved for BCF missing values args->verbosity = 1; args->record_cmd_line = 1; args->clevel = -1; args->unify_chr_names = 1; static struct option loptions[] = { {"force",0,0,1}, {"threads",required_argument,NULL,2}, {"help",0,0,'h'}, {"ncsq",1,0,'n'}, {"brief-predictions",no_argument,0,'b'}, {"trim-protein-seq",required_argument,0,'B'}, {"custom-tag",1,0,'c'}, {"local-csq",0,0,'l'}, {"gff-annot",1,0,'g'}, {"fasta-ref",1,0,'f'}, {"include",1,0,'i'}, {"exclude",1,0,'e'}, {"output",1,0,'o'}, {"output-type",1,NULL,'O'}, {"phase",1,0,'p'}, {"quiet",0,0,'q'}, {"verbose",1,0,'v'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,4}, {"samples",1,0,'s'}, {"samples-file",1,0,'S'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,5}, {"no-version",no_argument,NULL,3}, {"write-index",optional_argument,NULL,'W'}, {"dump-gff",required_argument,NULL,7}, {"unify-chr-names",required_argument,NULL,8}, {0,0,0,0} }; int c, targets_is_file = 0, regions_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; char *targets_list = NULL, *regions_list = NULL, *tmp; while ((c = getopt_long(argc, argv, "?hr:R:t:T:i:e:f:o:O:g:s:S:p:qc:ln:bB:v:W::",loptions,NULL)) >= 0) { switch (c) { case 1 : args->force = 1; break; case 2 : args->n_threads = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --threads %s\n", optarg); break; case 3 : args->record_cmd_line = 0; break; case 'b': args->brief_predictions = 1; fprintf(stderr,"Warning: The -b option will be removed in future versions. Please use -B 1 instead.\n"); break; case 'B': args->brief_predictions = strtol(optarg,&tmp,10); if ( *tmp || args->brief_predictions<1 ) error("Could not parse argument: --trim-protein-seq %s\n", optarg); break; case 'l': args->local_csq = 1; break; case 'c': args->bcsq_tag = optarg; break; case 'q': error("Error: the -q option has been deprecated, use -v, --verbose instead.\n"); break; case 'v': args->verbosity = atoi(optarg); if ( args->verbosity<0 || args->verbosity>2 ) error("Error: expected integer 0-2 with -v, --verbose\n"); break; case 'p': switch (optarg[0]) { case 'a': args->phase = PHASE_AS_IS; break; case 'm': args->phase = PHASE_MERGE; break; case 'r': args->phase = PHASE_REQUIRE; break; case 'R': args->phase = PHASE_NON_REF; break; case 's': args->phase = PHASE_SKIP; break; default: error("The -p code \"%s\" not recognised\n", optarg); } break; case 'f': args->fa_fname = optarg; break; case 'g': args->gff_fname = optarg; break; case 'n': args->ncsq2_max = 2 * atoi(optarg); if ( args->ncsq2_max <= 0 ) error("Expected positive integer with -n, got %s\n", optarg); break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 't': args->output_type = FT_TAB_TEXT; break; case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --output-type %s\n", optarg+1); } break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'r': regions_list = optarg; break; case 'R': regions_list = optarg; regions_is_file = 1; break; case 's': args->sample_list = optarg; break; case 'S': args->sample_list = optarg; args->sample_is_file = 1; break; case 't': targets_list = optarg; break; case 'T': targets_list = optarg; targets_is_file = 1; break; case 4 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 5 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 7 : args->dump_gff = optarg; break; case 8 : if ( !strcmp(optarg,"0") ) args->unify_chr_names = 0; else if ( !strcmp(optarg,"1") ) args->unify_chr_names = 1; else error("Could not parse: --unify-chr-names %s\n",optarg); break; case 'h': case '?': error("%s",usage()); default: error("The option not recognised: %s\n\n", optarg); break; } } char *fname = NULL; if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else error("%s", usage()); } else fname = argv[optind]; if ( argc - optind>1 ) error("%s", usage()); if ( !args->fa_fname ) error("Missing the --fasta-ref option\n"); if ( !args->gff_fname ) error("Missing the --gff option\n"); args->sr = bcf_sr_init(); if ( targets_list ) { bcf_sr_set_opt(args->sr,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->sr, targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", targets_list); } if ( regions_list ) { bcf_sr_set_opt(args->sr,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->sr, regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", regions_list); } if ( bcf_sr_set_threads(args->sr, args->n_threads)<0 ) error("Failed to create %d extra threads\n", args->n_threads); if ( !bcf_sr_add_reader(args->sr, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); init_data(args); while ( bcf_sr_next_line(args->sr) ) { process(args, &args->sr->readers[0].buffer[0]); } process(args,NULL); destroy_data(args); bcf_sr_destroy(args->sr); free(args); return 0; } bcftools-1.21/dbuf.h000066400000000000000000000034731467060157400143620ustar00rootroot00000000000000/* The MIT License Copyright (c) 2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Simple data buffer */ #ifndef __DBUF_H__ #define __DBUF_H__ #include typedef struct { size_t n,m; void **dat; } dbuf_t; static inline dbuf_t *dbuf_push(dbuf_t *buf, void *ptr) { if ( !buf ) buf = calloc(1,sizeof(dbuf_t)); buf->n++; hts_expand(void*,buf->n,buf->m,buf->dat); buf->dat[buf->n-1] = ptr; return buf; } static inline void *dbuf_ith(dbuf_t *buf, int i) { return buf->dat[i]; } static inline size_t dbuf_n(dbuf_t *buf) { return buf->n; } static inline void dbuf_destroy_free(dbuf_t *buf) { int i; for (i=0; in; i++) free(buf->dat[i]); free(buf->dat); free(buf); } #endif bcftools-1.21/dist.c000066400000000000000000000065161467060157400144010ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2020 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include "dist.h" extern void error(const char *format, ...); struct _dist_t { uint64_t *bins, nvalues; int nbins; int npow; // the number of orders of magnitude to represent exactly int nexact; // pow(10,npow) int nlevel; }; dist_t *dist_init(int npow) { dist_t *dist = (dist_t*) calloc(1,sizeof(dist_t)); dist->npow = npow; dist->nexact = pow(10,npow); dist->nlevel = dist->nexact - pow(10,npow-1); return dist; } void dist_destroy(dist_t *dist) { if ( !dist ) return; free(dist->bins); free(dist); } int dist_nbins(dist_t *dist) { return dist->nbins; } int dist_nvalues(dist_t *dist) { return dist->nvalues; } uint32_t dist_insert(dist_t *dist, uint32_t value) { int ibin; if ( value <= dist->nexact ) ibin = value; else { int npow = (int) log10(value); int level = npow - dist->npow + 1; uint32_t step = pow(10, level); ibin = dist->nexact + dist->nlevel*(level-1) + (value - pow(10,npow)) / step; } if ( ibin >= dist->nbins ) { dist->bins = (uint64_t*) realloc(dist->bins, sizeof(*dist->bins)*(ibin+1)); memset(dist->bins + dist->nbins, 0, (ibin+1 - dist->nbins)*sizeof(*dist->bins)); dist->nbins = ibin+1; } dist->bins[ibin]++; dist->nvalues++; return ibin; } uint32_t dist_insert_n(dist_t *dist, uint32_t value, uint32_t cnt) { if ( !cnt ) return 0; int ibin = dist_insert(dist, value); dist->bins[ibin] += cnt - 1; dist->nvalues += cnt; return ibin; } uint64_t dist_get(dist_t *dist, uint32_t idx, uint32_t *beg, uint32_t *end) { if ( idx < dist->nexact ) { if ( beg ) *beg = idx; if ( end ) *end = idx + 1; } else { int level = (idx - dist->nexact) / dist->nlevel + 1; int bin = idx - dist->nexact - dist->nlevel*(level-1); uint32_t step = pow(10, level); uint32_t value = pow(10, level + dist->npow - 1) + step*bin; if ( beg ) *beg = value; if ( end ) *end = value + step; } return dist->bins[idx]; } bcftools-1.21/dist.h000066400000000000000000000054421467060157400144030ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2020 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Logarithmic binning Example of usage: // Initialize, make the binning exact up to 10^4, then add a log-step dist_t *dist = dist_init(4); // Insert values int i; for (i=0; i<1e6; i++) dist_insert(dist, i); // Number of bins used int n = dist_n(dist); // Now print the distribution uint32_t beg, end; for (i=0; i #include typedef struct _dist_t dist_t; /* * dist_init() - init bins */ dist_t *dist_init(int npow); void dist_destroy(dist_t *dist); /* dist_nbins() - get the number of bins */ int dist_nbins(dist_t *dist); /* dist_nvalues() - get the total number of values inserted */ int dist_nvalues(dist_t *dist); /* dist_insert() - insert new value dist_insert_n() - insert new value n times */ uint32_t dist_insert(dist_t *dist, uint32_t value); uint32_t dist_insert_n(dist_t *dist, uint32_t value, uint32_t cnt); /* dist_get() @idx: from the interval [0,dist_n-1] @beg,end: [beg,end) */ uint64_t dist_get(dist_t *dist, uint32_t idx, uint32_t *beg, uint32_t *end); #endif bcftools-1.21/doc/000077500000000000000000000000001467060157400140275ustar00rootroot00000000000000bcftools-1.21/doc/bcftools.1000066400000000000000000005552071467060157400157420ustar00rootroot00000000000000'\" t .\" Title: bcftools .\" Author: [see the "AUTHOR(S)" section] .\" Generator: Asciidoctor 2.0.16.dev .\" Date: 2024-09-12 .\" Manual: \ \& .\" Source: \ \& .\" Language: English .\" .TH "BCFTOOLS" "1" "2024-09-12" "\ \&" "\ \&" .ie \n(.g .ds Aq \(aq .el .ds Aq ' .ss \n[.ss] 0 .nh .ad l .de URL \fI\\$2\fP <\\$1>\\$3 .. .als MTO URL .if \n[.g] \{\ . mso www.tmac . am URL . ad l . . . am MTO . ad l . . . LINKSTYLE blue R < > .\} .SH "NAME" bcftools \- utilities for variant calling and manipulating VCFs and BCFs. .SH "SYNOPSIS" .sp \fBbcftools\fP [\-\-version|\-\-version\-only] [\-\-help] [\fICOMMAND\fP] [\fIOPTIONS\fP] .SH "DESCRIPTION" .sp BCFtools is a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF\-compressed. .sp Most commands accept VCF, bgzipped VCF and BCF with filetype detected automatically even when streaming from a pipe. Indexed VCF and BCF will work in all situations. Un\-indexed VCF and BCF and streams will work in most, but not all situations. In general, whenever multiple VCFs are read simultaneously, they must be indexed and therefore also compressed. (Note that files with non\-standard index names can be accessed as e.g. "\f(CRbcftools view \-r X:2928329 file.vcf.gz##idx##non\-standard\-index\-name\fP".) .sp BCFtools is designed to work on a stream. It regards an input file "\-" as the standard input (stdin) and outputs to the standard output (stdout). Several commands can thus be combined with Unix pipes. .SS "VERSION" .sp This manual page was last updated \fB2024\-09\-12\fP and refers to bcftools git version \fB1.21\fP. .SS "BCF1" .sp The obsolete BCF1 format output by versions of samtools <= 0.1.19 is \fBnot\fP compatible with this version of bcftools. To read BCF1 files one can use the view command from old versions of bcftools packaged with samtools versions <= 0.1.19 to convert to VCF, which can then be read by this version of bcftools. .sp .if n .RS 4 .nf .fam C samtools\-0.1.19/bcftools/bcftools view file.bcf1 | bcftools view .fam .fi .if n .RE .SS "VARIANT CALLING" .sp See \fIbcftools call\fP for variant calling from the output of the \fIsamtools mpileup\fP command. In versions of samtools <= 0.1.19 calling was done with \fIbcftools view\fP. Users are now required to choose between the old samtools calling model (\fI\-c/\-\-consensus\-caller\fP) and the new multiallelic calling model (\fI\-m/\-\-multiallelic\-caller\fP). The multiallelic calling model is recommended for most tasks. .SS "FILTERING EXPRESSIONS" .sp See \fBEXPRESSIONS\fP .SH "LIST OF COMMANDS" .sp For a full list of available commands, run \fBbcftools\fP without arguments. For a full list of available options, run \fBbcftools\fP \fICOMMAND\fP without arguments. .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBannotate\fP .. edit VCF files, add or remove annotations .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBcall\fP .. SNP/indel calling (former "view") .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBcnv\fP .. Copy Number Variation caller .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBconcat\fP .. concatenate VCF/BCF files from the same set of samples .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBconsensus\fP .. create consensus sequence by applying VCF variants .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBconvert\fP .. convert VCF/BCF to other formats and back .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBcsq\fP .. haplotype aware consequence caller .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBfilter\fP .. filter VCF/BCF files using fixed thresholds .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBgtcheck\fP .. check sample concordance, detect sample swaps and contamination .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBhead\fP .. view VCF/BCF file headers .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBindex\fP .. index VCF/BCF .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBisec\fP .. intersections of VCF/BCF files .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBmerge\fP .. merge VCF/BCF files files from non\-overlapping sample sets .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBmpileup\fP .. multi\-way pileup producing genotype likelihoods .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBnorm\fP .. normalize indels .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBplugin\fP .. run user\-defined plugin .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBpolysomy\fP .. detect contaminations and whole\-chromosome aberrations .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBquery\fP .. transform VCF/BCF into user\-defined formats .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBreheader\fP .. modify VCF/BCF header, change sample names .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBroh\fP .. identify runs of homo/auto\-zygosity .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBsort\fP .. sort VCF/BCF files .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBstats\fP .. produce VCF/BCF stats (former vcfcheck) .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBview\fP .. subset, filter and convert VCF and BCF files .RE .SH "LIST OF SCRIPTS" .sp Some helper scripts are bundled with the bcftools code. .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBgff2gff\fP .. converts a GFF file to the format required by \fBcsq\fP .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} \fBplot\-vcfstats\fP .. plots the output of \fBstats\fP .RE .SH "COMMANDS AND OPTIONS" .SS "Common Options" .sp The following options are common to many bcftools commands. See usage for specific commands to see if they apply. .sp \fIFILE\fP .RS 4 Files can be both VCF or BCF, uncompressed or BGZF\-compressed. The file "\-" is interpreted as standard input. Some tools may require tabix\- or CSI\-indexed files. .RE .sp \fB\-c, \-\-collapse\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIall\fP|\fIsome\fP|\fInone\fP|\fIid\fP .RS 4 Controls how to treat records with duplicate positions and defines compatible records across multiple input files. Here by "compatible" we mean records which should be considered as identical by the tools. For example, when performing line intersections, the desire may be to consider as identical all sites with matching positions (\fBbcftools isec \-c\fP \fIall\fP), or only sites with matching variant type (\fBbcftools isec \-c\fP \fIsnps\fP\~ \fB\-c\fP \fIindels\fP), or only sites with all alleles identical (\fBbcftools isec \-c\fP \fInone\fP). .sp \fInone\fP .RS 4 only records with identical REF and ALT alleles are compatible .RE .sp \fIsome\fP .RS 4 only records where some subset of ALT alleles match are compatible .RE .sp \fIall\fP .RS 4 all records are compatible, regardless of whether the ALT alleles match or not. In the case of records with the same position, only the first will be considered and appear on output. .RE .sp \fIsnps\fP .RS 4 any SNP records are compatible, regardless of whether the ALT alleles match or not. For duplicate positions, only the first SNP record will be considered and appear on output. .RE .sp \fIindels\fP .RS 4 all indel records are compatible, regardless of whether the REF and ALT alleles match or not. For duplicate positions, only the first indel record will be considered and appear on output. .RE .sp \fIboth\fP .RS 4 abbreviation of "\fB\-c\fP \fIindels\fP\~ \fB\-c\fP \fIsnps\fP" .RE .sp \fIid\fP .RS 4 only records with identical ID column are compatible. Supported by \fBbcftools merge\fP only. .RE .RE .sp \fB\-f, \-\-apply\-filters\fP \fILIST\fP .RS 4 Skip sites where FILTER column does not contain any of the strings listed in \fILIST\fP. For example, to include only sites which have no filters set, use \fB\-f\fP \fI.,PASS\fP. .RE .sp \fB\-\-no\-version\fP .RS 4 Do not append version and command line information to the output VCF header. .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 When output consists of a single stream, write it to \fIFILE\fP rather than to standard output, where it is written by default. The file type is determined automatically from the file name suffix and in case a conflicting \fB\-O\fP option is given, the file name suffix takes precedence. .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 Output compressed BCF (\fIb\fP), uncompressed BCF (\fIu\fP), compressed VCF (\fIz\fP), uncompressed VCF (\fIv\fP). Use the \-Ou option when piping between bcftools subcommands to speed up performance by removing unnecessary compression/decompression and VCF\(<-\(->BCF conversion. \~ The compression level of the compressed formats (\fIb\fP and \fIz\fP) can be set by by appending a number between 0\-9. .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:beg\-end\fP|\fIchr:beg\-\fP[,...] .RS 4 Comma\-separated list of regions, see also \fB\-R, \-\-regions\-file\fP. Overlapping records are matched even when the starting coordinate is outside of the region, unlike the \fB\-t/\-T\fP options where only the POS coordinate is checked. Note that \fB\-r\fP cannot be used in combination with \fB\-R\fP. .RE .sp \fB\-R, \-\-regions\-file\fP \fIFILE\fP .RS 4 Regions can be specified either on command line or in a VCF, BED, or tab\-delimited file (the default). The columns of the tab\-delimited file can contain either positions (two\-column format: CHROM, POS) or intervals (three\-column format: CHROM, BEG, END), but not both. Positions are 1\-based and inclusive. The columns of the tab\-delimited BED file are also CHROM, POS and END (trailing columns are ignored), but coordinates are 0\-based, half\-open. To indicate that a file be treated as BED rather than the 1\-based tab\-delimited file, the file must have the ".bed" or ".bed.gz" suffix (case\-insensitive). Uncompressed files are stored in memory, while bgzip\-compressed and tabix\-indexed region files are streamed. Note that sequence names must match exactly, "chr20" is not the same as "20". Also note that chromosome ordering in \fIFILE\fP will be respected, the VCF will be processed in the order in which chromosomes first appear in \fIFILE\fP. However, within chromosomes, the VCF will always be processed in ascending genomic coordinate order no matter what order they appear in \fIFILE\fP. Note that overlapping regions in \fIFILE\fP can result in duplicated out of order positions in the output. This option requires indexed VCF/BCF files. Note that \fB\-R\fP cannot be used in combination with \fB\-r\fP. .RE .sp \fB\-\-regions\-overlap\fP \fIpos\fP|\fIrecord\fP|\fIvariant\fP|\fI0\fP|\fI1\fP|\fI2\fP .RS 4 This option controls how overlapping records are determined: set to \fBpos\fP or \fB0\fP if the VCF record has to have POS inside a region (this corresponds to the default behavior of \fB\-t/\-T\fP); set to \fBrecord\fP or \fB1\fP if also overlapping records with POS outside a region should be included (this is the default behavior of \fB\-r/\-R\fP, and includes indels with POS at the end of a region, which are technically outside the region); or set to \fBvariant\fP or \fB2\fP to include only true overlapping variation (compare the full VCF representation "\f(CRTA>T\-\fP" vs the true sequence variation "\f(CRA>\-\fP"). .RE .sp \fB\-s, \-\-samples\fP [^]\fILIST\fP .RS 4 Comma\-separated list of samples to include or exclude if prefixed with "^." (Note that when multiple samples are to be excluded, the "^" prefix is still present only once, e.g. "^SAMPLE1,SAMPLE2".) The sample order is updated to reflect that given on the command line. Note that in general tags such as INFO/AC, INFO/AN, etc are not updated to correspond to the subset samples. \fBbcftools view\fP is the exception where some tags will be updated (unless the \fB\-I, \-\-no\-update\fP option is used; see \fBbcftools view\fP documentation). To use updated tags for the subset in another command one can pipe from \fBview\fP into that command. For example: .RE .sp .if n .RS 4 .nf .fam C bcftools view \-Ou \-s sample1,sample2 file.vcf | bcftools query \-f %INFO/AC\(rst%INFO/AN\(rsn .fam .fi .if n .RE .sp \fB\-S, \-\-samples\-file\fP [^]\fIFILE\fP .RS 4 File of sample names to include or exclude if prefixed with "^". One sample per line. See also the note above for the \fB\-s, \-\-samples\fP option. The sample order is updated to reflect that given in the input file. The command \fBbcftools call\fP accepts an optional second column indicating ploidy (0, 1 or 2) or sex (as defined by \fB\-\-ploidy\fP, for example "F" or "M"), for example: .RE .sp .if n .RS 4 .nf .fam C sample1 1 sample2 2 sample3 2 .fam .fi .if n .RE .sp or .sp .if n .RS 4 .nf .fam C sample1 M sample2 F sample3 F .fam .fi .if n .RE .sp If the second column is not present, the sex "F" is assumed. With \fBbcftools call \-C\fP \fItrio\fP, PED file is expected. The program ignores the first column and the last indicates sex (1=male, 2=female), for example: .sp .if n .RS 4 .nf .fam C ignored_column daughterA fatherA motherA 2 ignored_column sonB fatherB motherB 1 .fam .fi .if n .RE .sp \fB\-t, \-\-targets\fP [^]\fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 Similar as \fB\-r, \-\-regions\fP, but the next position is accessed by streaming the whole VCF/BCF rather than using the tbi/csi index. Both \fB\-r\fP and \fB\-t\fP options can be applied simultaneously: \fB\-r\fP uses the index to jump to a region and \fB\-t\fP discards positions which are not in the targets. Unlike \fB\-r\fP, targets can be prefixed with "^" to request logical complement. For example, "^X,Y,MT" indicates that sequences X, Y and MT should be skipped. Yet another difference between the \fB\-t/\-T\fP and \fB\-r/\-R\fP is that \fB\-r/\-R\fP checks for proper overlaps and considers both POS and the end position of an indel, while \fB\-t/\-T\fP considers the POS coordinate only (by default; see also \fB\-\-regions\-overlap\fP and \fB\-\-targets\-overlap\fP). Note that \fB\-t\fP cannot be used in combination with \fB\-T\fP. .RE .sp \fB\-T, \-\-targets\-file\fP [^]\fIFILE\fP .RS 4 Same \fB\-t, \-\-targets\fP, but reads regions from a file. Note that \fB\-T\fP cannot be used in combination with \fB\-t\fP. .sp With the \fBcall \-C\fP \fIalleles\fP command, third column of the targets file must be comma\-separated list of alleles, starting with the reference allele. Note that the file must be compressed and indexed. Such a file can be easily created from a VCF using: .RE .sp .if n .RS 4 .nf .fam C bcftools query \-f\*(Aq%CHROM\(rst%POS\(rst%REF,%ALT\(rsn\*(Aq file.vcf | bgzip \-c > als.tsv.gz && tabix \-s1 \-b2 \-e2 als.tsv.gz .fam .fi .if n .RE .sp \fB\-\-targets\-overlap\fP \fIpos\fP|\fIrecord\fP|\fIvariant\fP|\fI0\fP|\fI1\fP|\fI2\fP .RS 4 Same as \fB\-\-regions\-overlap\fP but for \fB\-t/\-T\fP. .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 Use multithreading with \fIINT\fP worker threads. The option is currently used only for the compression of the output stream, only when \fI\-\-output\-type\fP is \fIb\fP or \fIz\fP. Default: 0. .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output files. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. Defaults to CSI unless specified otherwise. Can be used only for compressed BCF and VCF output. .RE .SS "bcftools annotate \fI[OPTIONS]\fP \fIFILE\fP" .sp Add or remove annotations. .sp \fB\-a, \-\-annotations\fP \fIfile\fP .RS 4 Bgzip\-compressed and tabix\-indexed file with annotations. The file can be VCF, BED, or a tab\-delimited file with mandatory columns CHROM, POS (or, alternatively, FROM and TO), optional columns REF and ALT, and arbitrary number of annotation columns. BED files are expected to have the ".bed" or ".bed.gz" suffix (case\-insensitive), otherwise a tab\-delimited file is assumed. Note that in case of tab\-delimited file, the coordinates POS, FROM and TO are one\-based and inclusive. When REF and ALT are present, only matching VCF records will be annotated. If the END coordinate is present in the annotation file and given on command line as "\f(CR\-c ~INFO/END\fP", then VCF records will be matched also by the INFO/END coordinate. If ID is present in the annotation file and given as "\f(CR\-c ~ID\fP", then VCF records will be matched also by the ID column. \~ .br \~ .br When multiple ALT alleles are present in the annotation file (given as comma\-separated list of alleles), at least one must match one of the alleles in the corresponding VCF record. Similarly, at least one alternate allele from a multi\-allelic VCF record must be present in the annotation file. \~ .br \~ .br Missing values can be added by providing "." in place of actual value and using the missing value modifier with \fB\-c\fP, such as ".TAG". \~ .br \~ .br Note that flag types, such as "INFO/FLAG", can be annotated by including a field with the value "1" to set the flag, "0" to remove it, or "." to keep existing flags. See also \fB\-c, \-\-columns\fP and \fB\-h, \-\-header\-lines\fP. .RE .sp .if n .RS 4 .nf .fam C # Sample annotation file with columns CHROM, POS, STRING_TAG, NUMERIC_TAG 1 752566 SomeString 5 1 798959 SomeOtherString 6 .fam .fi .if n .RE .sp \fB\-c, \-\-columns\fP \fIlist\fP .RS 4 Comma\-separated list of columns or tags to carry over from the annotation file (see also \fB\-a, \-\-annotations\fP). If the annotation file is not a VCF/BCF, \fIlist\fP describes the columns of the annotation file and must include CHROM, POS (or, alternatively, FROM,TO or BEG,END), and optionally REF and ALT. Unused columns which should be ignored can be indicated by "\-". \~ .br \~ .br If the annotation file is a VCF/BCF, only the edited columns/tags must be present and their order does not matter. The columns ID, QUAL, FILTER, INFO and FORMAT can be edited, where INFO tags can be written both as "INFO/TAG" or simply "TAG", and FORMAT tags can be written as "FORMAT/TAG" or "FMT/TAG". The imported VCF annotations can be renamed as "DST_TAG:=SRC_TAG" or "FMT/DST_TAG:=FMT/SRC_TAG". \~ .br \~ .br To carry over all INFO annotations, use "INFO". To add all INFO annotations except "TAG", use "^INFO/TAG". By default, existing values are replaced. \~ .br \~ .br By default, existing tags are overwritten unless the source value is a missing value (i.e. "."). If also missing values should be carried over (and overwrite existing tags), use ".TAG" instead of "TAG". To add annotations without overwriting existing values (that is, to add tags that are absent or to add values to existing tags with missing values), use "+TAG" instead of "TAG". These can be combined, for example ".+TAG" can be used to add TAG even if the source value is missing but only if TAG does not exist in the target file; existing tags will not be overwritten. To append to existing values (rather than replacing or leaving untouched), use "=TAG" (instead of "TAG" or "+TAG"). To replace only existing values without modifying missing annotations, use "\-TAG". As a special case of this, if position needs to be replaced, mark the column with the new coordinate as "\-POS". (Note that in previous releases this used to be "~POS", now deprecated.) \~ .br \~ .br To match the record also by ID or INFO/END, in addition to REF and ALT, use "~ID" or "~INFO/END". Note that this works only for ID and POS, for other fields see the description of \fB\-i\fP below. \~ .br \~ .br If the annotation file is not a VCF/BCF, all new annotations must be defined via \fB\-h, \-\-header\-lines\fP. \~ .br \~ .br See also the \fB\-l, \-\-merge\-logic\fP option. \~ .br \~ .br \fBSummary of \f(CR\-c, \-\-columns\fP:\fP .RE .sp .if n .RS 4 .nf .fam C CHROM,POS,TAG .. match by chromosome and position, transfer annotation from TAG CHROM,POS,\-,TAG .. same as above, but ignore the third column of the annotation file CHROM,BEG,END,TAG .. match by region (BEG,END are synonymous to FROM,TO) CHROM,POS,REF,ALT .. match by CHROM, POS, REF and ALT DST_TAG:=SRC_TAG .. transfer the SRC_TAG using the new name DST_TAG INFO .. transfer all INFO annotations ^INFO/TAG .. transfer all INFO annotations except "TAG" TAG .. add or overwrite existing target value if source is not "." and skip otherwise +TAG .. add or overwrite existing target value only it is "." .TAG .. add or overwrite existing target value even if source is "." .+TAG .. add new but never overwrite existing tag, regardless of its value; can transfer "." if target does not exist \-TAG .. overwrite existing value, never add new if target does not exist =TAG .. do not overwrite but append value to existing tags ~FIELD .. use this column to match lines with \-i/\-e expression (see the description of \-i below) ~ID .. in addition to CHROM,POS,REF,ALT match by also ID ~INFO/END .. in addition to CHROM,POS,REF,ALT match by also INFO/END .fam .fi .if n .RE .sp \fB\-C, \-\-columns\-file\fP \fIfile\fP .RS 4 Read the list of columns from a file (normally given via the \fB\-c, \-\-columns\fP option). "\-" to skip a column of the annotation file. One column name per row, an additional space\- or tab\-separated field can be present to indicate the merge logic (normally given via the \fB\-l, \-\-merge\-logic\fP option). This is useful when many annotations are added at once. .RE .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP and the extension described in \fB\-i, \-\-include\fP below. .RE .sp \fB\-\-force\fP .RS 4 continue even when parsing errors, such as undefined tags, are encountered. Note this can be an unsafe operation and can result in corrupted BCF files. If this option is used, make sure to sanity check the result thoroughly. .RE .sp \fB\-h, \-\-header\-lines\fP \fIfile\fP .RS 4 Lines to append to the VCF header, see also \fB\-c, \-\-columns\fP and \fB\-a, \-\-annotations\fP. For example: .RE .sp .if n .RS 4 .nf .fam C ##INFO= ##INFO= .fam .fi .if n .RE .sp \fB\-I, \-\-set\-id\fP [+]\fIFORMAT\fP .RS 4 assign ID on the fly. The format is the same as in the \fBquery\fP command (see below). By default all existing IDs are replaced. If the format string is preceded by "+", only missing IDs will be set. For example, one can use .RE .sp .if n .RS 4 .nf .fam C bcftools annotate \-\-set\-id +\*(Aq%CHROM\(rs_%POS\(rs_%REF\(rs_%FIRST_ALT\*(Aq file.vcf .fam .fi .if n .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. \~ .br \~ .br Additionally, the command \fBbcftools annotate\fP supports expressions updated from the annotation file dynamically for each record: .RE .sp .if n .RS 4 .nf .fam C # The field \*(AqSTR\*(Aq from the \-a file is required to match INFO/TAG in VCF. In the first example # the alleles REF,ALT must match, in the second example they are ignored. The option \-k is required # to output also records that are not annotated. The third example shows the same concept with # a numerical expression. bcftools annotate \-a annots.tsv.gz \-c CHROM,POS,REF,ALT,SCORE,~STR \-i\*(AqTAG={STR}\*(Aq \-k input.vcf bcftools annotate \-a annots.tsv.gz \-c CHROM,POS,\-,\-,SCORE,~STR \-i\*(AqTAG={STR}\*(Aq \-k input.vcf bcftools annotate \-a annots.tsv.gz \-c CHROM,POS,\-,\-,SCORE,~INT \-i\*(AqTAG>{INT}\*(Aq \-k input.vcf .fam .fi .if n .RE .sp \fB\-k, \-\-keep\-sites\fP .RS 4 keep sites which do not pass \fB\-i\fP and \fB\-e\fP expressions instead of discarding them .RE .sp \fB\-l, \-\-merge\-logic\fP \fItag:first\fP|\fIappend\fP|\fIappend\-missing\fP|\fIunique\fP|\fIsum\fP|\fIavg\fP|\fImin\fP|\fImax\fP[,...] .RS 4 When multiple regions overlap a single record, this option defines how to treat multiple annotation values when setting \fItag\fP in the destination file: use the first encountered value ignoring the rest (\fIfirst\fP); append allowing duplicates (\fIappend\fP); append even if the appended value is missing, i.e. is a dot (\fIappend\-missing\fP); append discarding duplicate values (\fIunique\fP); sum the values (\fIsum\fP, numeric fields only); average the values (\fIavg\fP); use the minimum value (\fImin\fP) or the maximum (\fImax\fP). + Note that this option is intended for use with BED or TAB\-delimited annotation files only. Moreover, it is effective only when either \fIREF\fP and \fIALT\fP or \fIBEG\fP and \fIEND\fP \fB\-\-columns\fP are present . + Multiple rules can be given either as a comma\-separated list or giving the option multiple times. This is an experimental feature. .RE .sp \fB\-m, \-\-mark\-sites\fP \fITAG\fP .RS 4 annotate sites which are present ("+") or absent ("\-") in the \fB\-a\fP file with a new INFO/TAG flag .RE .sp \fB\-\-min\-overlap\fP \fIANN\fP:\*(AqVCF\*(Aq .RS 4 minimum overlap required as a fraction of the variant in the annotation \fB\-a\fP file (\fIANN\fP), in the target VCF file (\fI:VCF\fP), or both for reciprocal overlap (\fIANN:VCF\fP). By default overlaps of arbitrary length are sufficient. The option can be used only with the tab\-delimited annotation \fB\-a\fP file and with \fIBEG\fP and \fIEND\fP columns present. .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-pair\-logic\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIall\fP|\fIsome\fP|\fIexact\fP .RS 4 Controls how to match records from the annotation file to the target VCF. Effective only when \fB\-a\fP is a VCF or BCF. The option replaces the former uninuitive \fB\-\-collapse\fP. See \fBCommon Options\fP for more. .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-rename\-annots\fP \fIfile\fP .RS 4 rename annotations according to the map in \fIfile\fP, with "old_name new_name\(rsn" pairs separated by whitespaces, each on a separate line. The old name must be prefixed with the annotation type: INFO, FORMAT, or FILTER. .RE .sp \fB\-\-rename\-chrs\fP \fIfile\fP .RS 4 rename chromosomes according to the map in \fIfile\fP, with "old_name new_name\(rsn" pairs separated by whitespaces, each on a separate line. .RE .sp \fB\-s, \-\-samples\fP [^]\fILIST\fP .RS 4 subset of samples to annotate, see also \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 subset of samples to annotate. If the samples are named differently in the target VCF and the \fB\-a, \-\-annotations\fP VCF, the name mapping can be given as "src_name dst_name\(rsn", separated by whitespaces, each pair on a separate line. .RE .sp \fB\-\-single\-overlaps\fP .RS 4 use this option to keep memory requirements low with very large annotation files. Note, however, that this comes at a cost, only single overlapping intervals are considered in this mode. This was the default mode until the commit af6f0c9 (Feb 24 2019). .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-x, \-\-remove\fP \fIlist\fP .RS 4 List of annotations to remove. Use "FILTER" to remove all filters or "FILTER/SomeFilter" to remove a specific filter. Similarly, "INFO" can be used to remove all INFO tags and "FORMAT" to remove all FORMAT tags except GT. To remove all INFO tags except "FOO" and "BAR", use "^INFO/FOO,INFO/BAR" (and similarly for FORMAT and FILTER). "INFO" can be abbreviated to "INF" and "FORMAT" to "FMT". .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .sp \fBExamples:\fP .sp .if n .RS 4 .nf .fam C # Remove three fields bcftools annotate \-x ID,INFO/DP,FORMAT/DP file.vcf.gz # Remove all INFO fields and all FORMAT fields except for GT and PL bcftools annotate \-x INFO,^FORMAT/GT,FORMAT/PL file.vcf # Add ID, QUAL and INFO/TAG, not replacing TAG if already present bcftools annotate \-a src.bcf \-c ID,QUAL,+TAG dst.bcf # Carry over all INFO and FORMAT annotations except FORMAT/GT bcftools annotate \-a src.bcf \-c INFO,^FORMAT/GT dst.bcf # Annotate from a tab\-delimited file with six columns (the fifth is ignored), # first indexing with tabix. The coordinates are 1\-based. tabix \-s1 \-b2 \-e2 annots.tab.gz bcftools annotate \-a annots.tab.gz \-h annots.hdr \-c CHROM,POS,REF,ALT,\-,TAG file.vcf # Annotate from a tab\-delimited file with regions (1\-based coordinates, inclusive) tabix \-s1 \-b2 \-e3 annots.tab.gz bcftools annotate \-a annots.tab.gz \-h annots.hdr \-c CHROM,FROM,TO,TAG input.vcf # Annotate from a bed file (0\-based coordinates, half\-closed, half\-open intervals) bcftools annotate \-a annots.bed.gz \-h annots.hdr \-c CHROM,FROM,TO,TAG input.vcf # Transfer the INFO/END tag, matching by POS,REF,ALT and ID. This example assumes # that INFO/END is already present in the VCF header. bcftools annotate \-a annots.tab.gz \-c CHROM,POS,~ID,REF,ALT,INFO/END input.vcf # For (many) more examples see http://samtools.github.io/bcftools/howtos/annotate.html .fam .fi .if n .RE .SS "bcftools call \fI[OPTIONS]\fP \fIFILE\fP" .sp This command replaces the former \fBbcftools view\fP caller. Some of the original functionality has been temporarily lost in the process of transition under .URL "http://github.com/samtools/htslib" "htslib" "," but will be added back on popular demand. The original calling model can be invoked with the \fB\-c\fP option. .SS "File format options:" .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-ploidy\fP \fIASSEMBLY\fP[\fI?\fP] .RS 4 predefined ploidy, use \fIlist\fP (or any other unused word) to print a list of all predefined assemblies. Append a question mark to print the actual definition. See also \fB\-\-ploidy\-file\fP. .RE .sp \fB\-\-ploidy\-file\fP \fIFILE\fP .RS 4 ploidy definition given as a space/tab\-delimited list of CHROM, FROM, TO, SEX, PLOIDY. The SEX codes are arbitrary and correspond to the ones used by \fB\-\-samples\-file\fP. The default ploidy can be given using the starred records (see below), unlisted regions have ploidy 2. The default ploidy definition is .RE .sp .if n .RS 4 .nf .fam C X 1 60000 M 1 X 2699521 154931043 M 1 Y 1 59373566 M 1 Y 1 59373566 F 0 MT 1 16569 M 1 MT 1 16569 F 1 * * * M 2 * * * F 2 .fam .fi .if n .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "Input/output options:" .sp \fB\-A, \-\-keep\-alts\fP .RS 4 output all alternate alleles present in the alignments even if they do not appear in any of the genotypes .RE .sp \fB\-\fP*\fB, \-\-keep\-unseen\-allele\fP .RS 4 keep the unobserved allele <*> or , useful mainly for gVCF output .RE .sp \fB\-f, \-\-format\-fields\fP \fIlist\fP .RS 4 comma\-separated list of FORMAT fields to output for each sample. Currently GQ and GP fields are supported. For convenience, the fields can be given as lower case letters. Prefixed with "^" indicates a request for tag removal of auxiliary tags useful only for calling. .RE .sp \fB\-F, \-\-prior\-freqs\fP \fIAN\fP,\fIAC\fP .RS 4 take advantage of prior knowledge of population allele frequencies. The workflow looks like this: .RE .sp .if n .RS 4 .nf .fam C # Extract AN,AC values from an existing VCF, such 1000Genomes bcftools query \-f\*(Aq%CHROM\(rst%POS\(rst%REF\(rst%ALT\(rst%AN\(rst%AC\(rsn\*(Aq 1000Genomes.bcf | bgzip \-c > AFs.tab.gz # If the tags AN,AC are not already present, use the +fill\-tags plugin bcftools +fill\-tags 1000Genomes.bcf | bcftools query \-f\*(Aq%CHROM\(rst%POS\(rst%REF\(rst%ALT\(rst%AN\(rst%AC\(rsn\*(Aq | bgzip \-c > AFs.tab.gz tabix \-s1 \-b2 \-e2 AFs.tab.gz # Create a VCF header description, here we name the tags REF_AN,REF_AC cat AFs.hdr ##INFO= ##INFO= # Now before calling, stream the raw mpileup output through `bcftools annotate` to add the frequencies bcftools mpileup [...] \-Ou | bcftools annotate \-a AFs.tab.gz \-h AFs.hdr \-c CHROM,POS,REF,ALT,REF_AN,REF_AC \-Ou | bcftools call \-mv \-F REF_AN,REF_AC [...] .fam .fi .if n .RE .sp \fB\-G, \-\-group\-samples\fP \fIFILE\fP|\fI\-\fP .RS 4 by default, all samples are assumed to come from a single population. This option groups samples into populations and apply the HWE assumption within but not across the populations. \fIFILE\fP is a tab\-delimited text file with sample names in the first column and group names in the second column. If \fI\-\fP is given instead, no HWE assumption is made at all and single\-sample calling is performed. (Note that in low coverage data this inflates the rate of false positives.) The \fB\-G\fP option requires the presence of per\-sample FORMAT/QS or FORMAT/AD tag generated with \fBbcftools mpileup \-a QS\fP (or \fB\-a AD\fP). .RE .sp \fB\-g, \-\-gvcf\fP \fIINT\fP[,...] .RS 4 output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers. For example, passing \fI5,15\fP will group sites into two types of gVCF blocks, the first with minimum per\-sample DP from the interval [5,15) and the latter with minimum depth 15 or more. In this example, sites with minimum per\-sample depth less than 5 will be printed as separate records, outside of gVCF blocks. .RE .sp \fB\-i, \-\-insert\-missed\fP \fIINT\fP .RS 4 output also sites missed by mpileup but present in \fB\-T, \-\-targets\-file\fP. .RE .sp \fB\-M, \-\-keep\-masked\-ref\fP .RS 4 output sites where REF allele is N .RE .sp \fB\-V, \-\-skip\-variants\fP \fIsnps\fP|\fIindels\fP .RS 4 skip indel/SNP sites .RE .sp \fB\-v, \-\-variants\-only\fP .RS 4 output variant sites only .RE .SS "Consensus/variant calling options:" .sp \fB\-c, \-\-consensus\-caller\fP .RS 4 the original \fBsamtools\fP/\fBbcftools\fP calling method (conflicts with \fB\-m\fP) .RE .sp \fB\-C, \-\-constrain\fP \fIalleles\fP|\fItrio\fP .RS 4 .sp \fIalleles\fP .RS 4 call genotypes given alleles. See also \fB\-T, \-\-targets\-file\fP. .RE .sp \fItrio\fP .RS 4 call genotypes given the father\-mother\-child constraint. See also \fB\-s, \-\-samples\fP and \fB\-n, \-\-novel\-rate\fP. .RE .RE .sp \fB\-m, \-\-multiallelic\-caller\fP .RS 4 alternative model for multiallelic and rare\-variant calling designed to overcome known limitations in \fB\-c\fP calling model (conflicts with \fB\-c\fP) .RE .sp \fB\-n, \-\-novel\-rate\fP \fIfloat\fP[,...] .RS 4 likelihood of novel mutation for constrained \fB\-C\fP \fItrio\fP calling. The trio genotype calling maximizes likelihood of a particular combination of genotypes for father, mother and the child P(F=i,M=j,C=k) = P(unconstrained) * Pn + P(constrained) * (1\-Pn). By providing three values, the mutation rate Pn is set explicitly for SNPs, deletions and insertions, respectively. If two values are given, the first is interpreted as the mutation rate of SNPs and the second is used to calculate the mutation rate of indels according to their length as Pn=\fIfloat\fP*exp(\-a\-b*len), where a=22.8689, b=0.2994 for insertions and a=21.9313, b=0.2856 for deletions [pubmed:23975140]. If only one value is given, the same mutation rate Pn is used for SNPs and indels. .RE .sp \fB\-p, \-\-pval\-threshold\fP \fIfloat\fP .RS 4 with \fB\-c\fP, accept variant if P(ref|D) < \fIfloat\fP. .RE .sp \fB\-P, \-\-prior\fP \fIfloat\fP .RS 4 expected substitution rate, or 0 to disable the prior. Only with \fB\-m\fP. .RE .sp \fB\-t, \-\-targets\fP \fIfile\fP|\fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-X, \-\-chromosome\-X\fP .RS 4 haploid output for male samples (requires PED file with \fB\-s\fP) .RE .sp \fB\-Y, \-\-chromosome\-Y\fP .RS 4 haploid output for males and skips females (requires PED file with \fB\-s\fP) .RE .SS "bcftools cnv \fI[OPTIONS]\fP \fIFILE\fP" .sp Copy number variation caller, requires a VCF annotated with the Illumina\(cqs B\-allele frequency (BAF) and Log R Ratio intensity (LRR) values. The HMM considers the following copy number states: CN 2 (normal), 1 (single\-copy loss), 0 (complete loss), 3 (single\-copy gain). .SS "General Options:" .sp \fB\-c, \-\-control\-sample\fP \fIstring\fP .RS 4 optional control sample name. If given, pairwise calling is performed and the \fB\-P\fP option can be used .RE .sp \fB\-f, \-\-AF\-file\fP \fIfile\fP .RS 4 read allele frequencies from a tab\-delimited file with the columns CHR,POS,REF,ALT,AF .RE .sp \fB\-o, \-\-output\-dir\fP \fIpath\fP .RS 4 output directory .RE .sp \fB\-p, \-\-plot\-threshold\fP \fIfloat\fP .RS 4 call \fBmatplotlib\fP to produce plots for chromosomes with quality at least \fIfloat\fP, useful for visual inspection of the calls. With \fB\-p 0\fP, plots for all chromosomes will be generated. If not given, a \fBmatplotlib\fP script will be created but not called. .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-query\-sample\fP \fIstring\fP .RS 4 query sample name .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .SS "HMM Options:" .sp \fB\-a, \-\-aberrant\fP \fIfloat\fP[,\fIfloat\fP] .RS 4 fraction of aberrant cells in query and control. The hallmark of duplications and contaminations is the BAF value of heterozygous markers which is dependent on the fraction of aberrant cells. Sensitivity to smaller fractions of cells can be increased by setting \fB\-a\fP to a lower value. Note however, that this comes at the cost of increased false discovery rate. .RE .sp \fB\-b, \-\-BAF\-weight\fP \fIfloat\fP .RS 4 relative contribution from BAF .RE .sp \fB\-d, \-\-BAF\-dev\fP \fIfloat\fP[,\fIfloat\fP] .RS 4 expected BAF deviation in query and control, i.e. the noise observed in the data. .RE .sp \fB\-e, \-\-err\-prob\fP \fIfloat\fP .RS 4 uniform error probability .RE .sp \fB\-l, \-\-LRR\-weight\fP \fIfloat\fP .RS 4 relative contribution from LRR. With noisy data, this option can have big effect on the number of calls produced. In truly random noise (such as in simulated data), the value should be set high (1.0), but in the presence of systematic noise when LRR are not informative, lower values result in cleaner calls (0.2). .RE .sp \fB\-L, \-\-LRR\-smooth\-win\fP \fIint\fP .RS 4 reduce LRR noise by applying moving average given this window size .RE .sp \fB\-O, \-\-optimize\fP \fIfloat\fP .RS 4 iteratively estimate the fraction of aberrant cells, down to the given fraction. Lowering this value from the default 1.0 to say, 0.3, can help discover more events but also increases noise .RE .sp \fB\-P, \-\-same\-prob\fP \fIfloat\fP .RS 4 the prior probability of the query and the control sample being the same. Setting to 0 calls both independently, setting to 1 forces the same copy number state in both. .RE .sp \fB\-x, \-\-xy\-prob\fP \fIfloat\fP .RS 4 the HMM probability of transition to another copy number state. Increasing this values leads to smaller and more frequent calls. .RE .SS "bcftools concat \fI[OPTIONS]\fP \fIFILE1\fP \fIFILE2\fP [...]" .sp Concatenate or combine VCF/BCF files. All source files must have the same sample columns appearing in the same order. Can be used, for example, to concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel VCF into one. The input files must be sorted by chr and position. The files must be given in the correct order to produce sorted VCF on output unless the \fB\-a, \-\-allow\-overlaps\fP option is specified. With the \-\-naive option, the files are concatenated without being recompressed, which is very fast.. .sp \fB\-a, \-\-allow\-overlaps\fP .RS 4 First coordinate of the next file can precede last record of the current file. .RE .sp \fB\-c, \-\-compact\-PS\fP .RS 4 Do not output PS tag at each site, only at the start of a new phase set block. .RE .sp \fB\-d, \-\-rm\-dups\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIall\fP|\fIexact\fP .RS 4 Output duplicate records of specified type present in multiple files only once. Note that records duplicate within one file are not removed with this option, for that use \fBbcftools norm \-d\fP instead. .br In other words, the default behavior of the program is similar to unix "\f(CRcat\fP" in that when two files contain a record with the same position, that position will appear twice on output. With \fB\-d\fP, every line that finds a matching record in another file will be printed only once. .br Requires \fB\-a, \-\-allow\-overlaps\fP. .RE .sp \fB\-D, \-\-remove\-duplicates\fP .RS 4 Alias for \fB\-d exact\fP .RE .sp \fB\-f, \-\-file\-list\fP \fIFILE\fP .RS 4 Read file names from \fIFILE\fP, one file name per line. .RE .sp \fB\-l, \-\-ligate\fP .RS 4 Ligate phased VCFs by matching phase at overlapping haplotypes. Note that the option is intended for VCFs with perfect overlap, sites in overlapping regions present in one but missing in the other are dropped. .RE .sp \fB\-\-ligate\-force\fP .RS 4 Keep all sites and ligate even non\-overlapping chunks and chunks with imperfect overlap .RE .sp \fB\-\-ligate\-warn\fP .RS 4 Drop sites in imperfect overlaps .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-n, \-\-naive\fP .RS 4 Concatenate VCF or BCF files without recompression. This is very fast but requires that all files are of the same type (all VCF or all BCF) and have the same headers. This is because all tags and chromosome names in the BCF body rely on the order of the contig and tag definitions in the header. A header check compatibility is performed and the program throws an error if it is not safe to use the option. .RE .sp \fB\-\-naive\-force\fP .RS 4 Same as \-\-naive, but header compatibility is not checked. Dangerous, use with caution. .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-q, \-\-min\-PQ\fP \fIINT\fP .RS 4 Break phase set if phasing quality is lower than \fIINT\fP .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP. Requires \fB\-a, \-\-allow\-overlaps\fP. .RE .sp \fB\-R, \-\-regions\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP. Requires \fB\-a, \-\-allow\-overlaps\fP. .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "bcftools consensus \fI[OPTIONS]\fP \fIFILE\fP" .sp Create consensus sequence by applying VCF variants to a reference fasta file. By default, the program will apply all ALT variants to the reference fasta to obtain the consensus sequence. Using the \fB\-\-sample\fP (and, optionally, \fB\-\-haplotype\fP) option will apply genotype (haplotype) calls from FORMAT/GT. Note that the program does not act as a primitive variant caller and ignores allelic depth information, such as INFO/AD or FORMAT/AD. For that, consider using the \fBsetGT\fP plugin. .sp \fB\-a, \-\-absent\fP \fICHAR\fP .RS 4 replace positions absent from VCF with CHAR .RE .sp \fB\-c, \-\-chain\fP \fIFILE\fP .RS 4 write a chain file for liftover .RE .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-f, \-\-fasta\-ref\fP \fIFILE\fP .RS 4 reference sequence in fasta format .RE .sp \fB\-H, \-\-haplotype\fP N|\fIR\fP|\fIA\fP|\fII\fP|\fILR\fP|\fILA\fP|\fISR\fP|\fISA\fP|\fINpIu\fP .RS 4 choose which allele from the FORMAT/GT field to use (the codes are case\-insensitive): .sp \fIN\fP .RS 4 N={1,2,3,...}, the allele index within the genotype, regardless of phasing .RE .sp \fIR\fP .RS 4 the REF allele (in heterozygous genotypes) .RE .sp \fIA\fP .RS 4 the ALT allele (in heterozygous genotypes) .RE .sp \fII\fP .RS 4 IUPAC code for all genotypes .RE .sp \fILR, LA\fP .RS 4 the longer allele. If both have the same length, use the REF allele (LR), or the ALT allele (LA) .RE .sp \fISR, SA\fP .RS 4 the shorter allele. If both have the same length, use the REF allele (SR), or the ALT allele (SA) .RE .sp \fINpIu\fP .RS 4 N={1,2,3,...}, the allele index within genotype for phased genotypes and IUPAC code for unphased genotypes. For example, \fI1pIu\fP or \fI2pIu\fP .RE .RE .sp Note that the \fB\-H, \-\-haplotype\fP option requires the \fB\-s, \-\-samples\fP option, unless exactly one sample is present in the VCF .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-I, \-\-iupac\-codes\fP .RS 4 output variants in the form of IUPAC ambiguity codes determined from FORMAT/GT fields. By default all samples are used and can be subset with \fB\-s, \-\-samples\fP and \fB\-S, \-\-samples\-file\fP. Use \fB\-s \-\fP to ignore samples and use only the REF and ALT columns. NOTE: prior to version 1.17 the IUPAC codes were determined solely from REF,ALT columns and sample genotypes were not considered. .RE .sp \fB\-\-mark\-del\fP \fICHAR\fP .RS 4 instead of removing sequence, insert character CHAR for deletions .RE .sp \fB\-\-mark\-ins\fP \fIuc\fP|\fIlc\fP|\fICHAR\fP .RS 4 highlight inserted sequence in uppercase (uc), lowercase (lc), or a provided character CHAR, leaving the rest of the sequence as is .RE .sp \fB\-\-mark\-snv\fP \fIuc\fP|\fIlc\fP .RS 4 highlight substitutions in uppercase (uc), lowercase (lc), or a provided character CHAR, leaving the rest of the sequence as is .RE .sp \fB\-m, \-\-mask\fP \fIFILE\fP .RS 4 BED file or TAB file with regions to be replaced with N (the default) or as specified by the next \fB\-\-mask\-with\fP option. See discussion of \fB\-\-regions\-file\fP in \fBCommon Options\fP for file format details. .RE .sp \fB\-\-mask\-with\fP \fICHAR\fP|\fIlc\fP|\fIuc\fP .RS 4 replace sequence from \fB\-\-mask\fP with CHAR, skipping overlapping variants, or change to lowercase (lc) or uppercase (uc) .RE .sp \fB\-M, \-\-missing\fP \fICHAR\fP .RS 4 instead of skipping the missing genotypes, output the character CHAR (e.g. "?") .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 write output to a file .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 how to treat VCF variants overlapping the target region in the fasta file: see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 apply variants of the listed samples. See also the option \fB\-I, \-\-iupac\-codes\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 apply variants of the samples listed in the file. See also the option \fB\-I, \-\-iupac\-codes\fP .RE .sp \fBExamples:\fP .sp .if n .RS 4 .nf .fam C # Apply variants present in sample "NA001", output IUPAC codes for hets bcftools consensus \-i \-s NA001 \-f in.fa in.vcf.gz > out.fa # Create consensus for one region. The fasta header lines are then expected # in the form ">chr:from\-to". Ignore samples and consider only the REF and ALT columns samtools faidx ref.fa 8:11870\-11890 | bcftools consensus \-s \- in.vcf.gz \-o out.fa # For more examples see http://samtools.github.io/bcftools/howtos/consensus\-sequence.html .fam .fi .if n .RE .sp \fBNotes:\fP .RS 4 Masking options are applied in the following order .sp .RS 4 .ie n \{\ \h'-04' 1.\h'+01'\c .\} .el \{\ . sp -1 . IP " 1." 4.2 .\} mask regions with \fB\-\-mask\-with\fP character if \fB\-\-mask\fP is given. All overlapping VCF variants are ignored .RE .sp .RS 4 .ie n \{\ \h'-04' 2.\h'+01'\c .\} .el \{\ . sp -1 . IP " 2." 4.2 .\} replace sequence not mentioned in the VCF with the requested character if \fB\-\-absent\fP is given .RE .sp .RS 4 .ie n \{\ \h'-04' 3.\h'+01'\c .\} .el \{\ . sp -1 . IP " 3." 4.2 .\} finally apply \fB\-\-mark\-del\fP, \fB\-\-mark\-ins\fP, \fB\-\-mark\-snv\fP masks .RE .RE .SS "bcftools convert \fI[OPTIONS]\fP \fIFILE\fP" .SS "VCF input options:" .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "VCF output options:" .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .SS "GEN/SAMPLE conversion:" .sp \fB\-G, \-\-gensample2vcf\fP \fIprefix\fP or \fIgen\-file\fP,\fIsample\-file\fP .RS 4 convert IMPUTE2 output to VCF. One of the ID columns ("SNP ID" or "rsID" in .URL "https://www.cog\-genomics.org/plink/2.0/formats#gen" "" ")" must be of the form "CHROM:POS_REF_ALT" to detect possible strand swaps. \~ .br When the \fB\-\-vcf\-ids\fP option is given, the other column (autodetected) is used to fill the ID column of the VCF. \~ .br See also \fB\-g\fP and \fB\-\-3N6\fP options. .RE .sp \fB\-g, \-\-gensample\fP \fIprefix\fP or \fIgen\-file\fP,\fIsample\-file\fP .RS 4 convert from VCF to gen/sample format used by IMPUTE2 and SHAPEIT. The columns of .gen file format are ID1,ID2,POS,A,B followed by three genotype probabilities P(AA), P(AB), P(BB) for each sample. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". When the \fB\-\-vcf\-ids\fP option is given, the second column is set to match the ID column of the VCF. \~ .br See also \fB\-G\fP and \fB\-\-3N6\fP options. \~ .br The file .gen and .sample file format are: .RE .sp .if n .RS 4 .nf .fam C .gen (with \-\-3N6 \-\-vcf\-ids) \-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\- chr1 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1 0 chr1 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 0 1 .gen (with \-\-vcf\-ids) \-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\- 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1 0 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 0 1 .gen (the default) \-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\- 1:111485207_G_A 1:111485207_G_A 111485207 G A 0 1 0 0 1 0 1:111494194_C_T 1:111494194_C_T 111494194 C T 0 1 0 0 0 1 .sample \-\-\-\-\-\-\- ID_1 ID_2 missing 0 0 0 sample1 sample1 0 sample2 sample2 0 .fam .fi .if n .RE .sp \fB\-\-3N6\fP .RS 4 Expect/Create files in the 3*N+6 column format. This is the new .gen file format with the first column containing the chromosome name, see \c .URL "https://www.cog\-genomics.org/plink/2.0/formats#gen" "" "" .RE .sp \fB\-\-tag\fP \fISTRING\fP .RS 4 tag to take values for .gen file: GT,PL,GL,GP .RE .sp \fB\-\-sex\fP \fIFILE\fP .RS 4 output sex column in the sample file. The FILE format is .RE .sp .if n .RS 4 .nf .fam C MaleSample M FemaleSample F .fam .fi .if n .RE .sp \fB\-\-vcf\-ids\fP .RS 4 output VCF IDs in the second column instead of CHROM:POS_REF_ALT .RE .SS "gVCF conversion:" .sp \fB\-\-gvcf2vcf\fP .RS 4 convert gVCF to VCF, expanding REF blocks into sites. Note that the \fB\-i\fP and \fB\-e\fP options work differently with this switch. In this situation the filtering expressions define which sites should be expanded and which sites should be left unmodified, but all sites are printed on output. In order to drop sites, stream first through \fBbcftools view\fP. .RE .sp \fB\-f, \-\-fasta\-ref\fP \fIfile\fP .RS 4 reference sequence in fasta format. Must be indexed with samtools faidx .RE .SS "HAP/SAMPLE conversion:" .sp \fB\-\-hapsample2vcf\fP \fIprefix\fP or \fIhap\-file\fP,\fIsample\-file\fP .RS 4 convert from hap/sample format to VCF. The columns of .hap file are similar to .gen file above, but there are only two haplotype columns per sample. Note that the first or the second column of the .hap file is expected to be in the form "CHR:POS_REF_ALT[_END]", with the _END being optional for defining the INFO/END tag when ALT is a symbolic allele. For example: .RE .sp .if n .RS 4 .nf .fam C .hap (with \-\-vcf\-ids) \-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\- 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1:111495231_A__111495784 rsID3 111495231 A 0 0 1 0 .hap (the default) \-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\-\- 1 1:111485207_G_A 111485207 G A 0 1 0 0 1 1:111495231_A__111495784 111495231 A 0 0 1 0 .fam .fi .if n .RE .sp \fB\-\-hapsample\fP \fIprefix\fP or \fIhap\-file\fP,\fIsample\-file\fP .RS 4 convert from VCF to hap/sample format used by IMPUTE2 and SHAPEIT. The columns of .hap file begin with ID,RSID,POS,REF,ALT. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". .RE .sp \fB\-\-haploid2diploid\fP .RS 4 with \fB\-h\fP option converts haploid genotypes to homozygous diploid genotypes. For example, the program will print \fI0 0\fP instead of the default \fI0 \-\fP. This is useful for programs which do not handle haploid genotypes correctly. .RE .sp \fB\-\-sex\fP \fIFILE\fP .RS 4 output sex column in the sample file. The FILE format is .RE .sp .if n .RS 4 .nf .fam C MaleSample M FemaleSample F .fam .fi .if n .RE .sp \fB\-\-vcf\-ids\fP .RS 4 the second column of the .hap file holds the VCF ids, the first column is of the form "CHR:POS_REF_ALT[_END]". Without the option, the format follows \c .URL "https://www.cog\-genomics.org/plink/2.0/formats#haps" "" with ids (the second column) of the form "CHR:POS_REF_ALT[_END]" .RE .SS "HAP/LEGEND/SAMPLE conversion:" .sp \fB\-H, \-\-haplegendsample2vcf\fP \fIprefix\fP or \fIhap\-file\fP,\fIlegend\-file\fP,\fIsample\-file\fP .RS 4 convert from hap/legend/sample format used by IMPUTE2 to VCF. See also \fB\-h, \-\-hapslegendsample\fP below. .RE .sp \fB\-h, \-\-haplegendsample\fP \fIprefix\fP or \fIhap\-file\fP,\fIlegend\-file\fP,\fIsample\-file\fP .RS 4 convert from VCF to hap/legend/sample format used by IMPUTE2 and SHAPEIT. The columns of .legend file ID,POS,REF,ALT. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". The .sample file is quite basic at the moment with columns for population, group and sex expected to be edited by the user. For example: .RE .sp .if n .RS 4 .nf .fam C .hap \-\-\-\-\- 0 1 0 0 1 0 0 1 0 0 0 1 .legend \-\-\-\-\-\-\- id position a0 a1 1:111485207_G_A 111485207 G A 1:111494194_C_T 111494194 C T .sample \-\-\-\-\-\-\- sample population group sex sample1 sample1 sample1 2 sample2 sample2 sample2 2 .fam .fi .if n .RE .sp \fB\-\-haploid2diploid\fP .RS 4 with \fB\-h\fP option converts haploid genotypes to homozygous diploid genotypes. For example, the program will print \fI0 0\fP instead of the default \fI0 \-\fP. This is useful for programs which do not handle haploid genotypes correctly. .RE .sp \fB\-\-sex\fP \fIFILE\fP .RS 4 output sex column in the sample file. The FILE format is .RE .sp .if n .RS 4 .nf .fam C MaleSample M FemaleSample F .fam .fi .if n .RE .sp \fB\-\-vcf\-ids\fP .RS 4 output VCF IDs instead of "CHROM:POS_REF_ALT". Note that this option can be used with \fB\-\-haplegendsample\fP but not with \fB\-\-haplegendsample2vcf\fP. .RE .SS "TSV conversion:" .sp \fB\-\-tsv2vcf\fP \fIfile\fP .RS 4 convert from TSV (tab\-separated values) format (such as generated by 23andMe) to VCF. The input file fields can be tab\- or space\- delimited .RE .sp \fB\-c, \-\-columns\fP \fIlist\fP .RS 4 comma\-separated list of fields in the input file. In the current version, the fields CHROM, POS, ID, and AA or REF, ALT are expected and can appear in arbitrary order. Columns which should be ignored in the input file can be indicated by "\-". The AA field lists alleles on the forward reference strand, for example "CC" or "CT" for diploid genotypes or "C" for haploid genotypes (sex chromosomes). Insertions and deletions are supported only with REF and ALT but not with AA. Missing data can be indicated with "\-\-" or ".". .RE .sp \fB\-f, \-\-fasta\-ref\fP \fIfile\fP .RS 4 reference sequence in fasta format. Must be indexed with samtools faidx .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 list of sample names. See \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 file of sample names. See \fBCommon Options\fP .RE .sp \fBExample:\fP .sp .if n .RS 4 .nf .fam C # Convert 23andme results into VCF bcftools convert \-c ID,CHROM,POS,AA \-s SampleName \-f 23andme\-ref.fa \-\-tsv2vcf 23andme.txt \-o out.vcf.gz # Convert tab\-delimited file into a sites\-only VCF (no genotypes), in this example first column to be ignored bcftools convert \-c \-,CHROM,POS,REF,ALT \-f ref.fa \-\-tsv2vcf calls.txt \-o out.bcf .fam .fi .if n .RE .SS "bcftools csq \fI[OPTIONS]\fP \fIFILE\fP" .sp Haplotype aware consequence predictor which correctly handles combined variants such as MNPs split over multiple VCF records, SNPs separated by an intron (but adjacent in the spliced transcript) or nearby frame\-shifting indels which in combination in fact are not frame\-shifting. .sp The output VCF is annotated with INFO/BCSQ and FORMAT/BCSQ tag (configurable with the \fB\-c\fP option). The latter is a bitmask of indexes to INFO/BCSQ, with interleaved haplotypes. See the usage examples below for using the %TBCSQ converter in \fBquery\fP for extracting a more human readable form from this bitmask. The construction of the bitmask limits the number of consequences that can be referenced per sample in the FORMAT/BCSQ tags. By default this is 15, but if more are required, see the \fB\-\-ncsq\fP option. .sp Note that the program annotates only records with a functional consequence and intergenic regions will pass through unchanged. .sp The program requires on input a VCF/BCF file, the reference genome in fasta format (\fB\-\-fasta\-ref\fP) and genomic features in the GFF3 format downloadable from the Ensembl website (\fB\-\-gff\-annot\fP), and outputs an annotated VCF/BCF file. Currently, only Ensembl GFF3 files are supported. .sp By default, the input VCF should be phased. If phase is unknown, or only partially known, the \fB\-\-phase\fP option can be used to indicate how to handle unphased data. Alternatively, haplotype aware calling can be turned off with the \fB\-\-local\-csq\fP option. .sp If conflicting (overlapping) variants within one haplotype are detected, a warning will be emitted and predictions will be based on only the first variant in the analysis. .sp Symbolic alleles are not supported. They will remain unannotated in the output VCF and are ignored for the prediction analysis. .sp \fB\-c, \-\-custom\-tag\fP \fISTRING\fP .RS 4 use this custom tag to store consequences rather than the default BCSQ tag .RE .sp \fB\-B, \-\-trim\-protein\-seq\fP \fIINT\fP .RS 4 abbreviate protein\-changing predictions to maximum of INT aminoacids. For example, instead of writing the whole modified protein sequence with potentially hundreds of aminoacids, with \fB\-B 1\fP only an abbreviated version such as \fI25E..329>25G..94\fP will be written. .RE .sp \fB\-\-dump\-gff\fP \fIFILE\fP .RS 4 dump the parsed GFF into a gzipped FILE. Intended for debugging purposes, shows how is the input GFF viewed by the program. .RE .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-f, \-\-fasta\-ref\fP \fIFILE\fP .RS 4 reference sequence in fasta format (required) .RE .sp \fB\-\-force\fP .RS 4 run even if some sanity checks fail. Currently the option enables skipping transcripts in malformatted GFFs with incorrect phase .RE .sp \fB\-g, \-\-gff\-annot\fP \fIFILE\fP .RS 4 GFF3 annotation file (required), such as \c .URL "http://ftp.ensembl.org/pub/current_gff3/homo_sapiens/" "" "." The script \fBgff2gff\fP can help with conversion from non\-standard GFF formats. An example of a minimal working GFF file: .RE .sp .if n .RS 4 .nf .fam C # The program looks for "CDS", "exon", "three_prime_UTR" and "five_prime_UTR" lines, # looks up their parent transcript (determined from the "Parent=transcript:" attribute), # the gene (determined from the transcript\*(Aqs "Parent=gene:" attribute), and the biotype # (the most interesting is "protein_coding"). # # Empty and commented lines are skipped, the following GFF columns are required # 1. chromosome # 2. IGNORED # 3. type (CDS, exon, three_prime_UTR, five_prime_UTR, gene, transcript, etc.) # 4. start of the feature (1\-based) # 5. end of the feature (1\-based) # 6. IGNORED # 7. strand (+ or \-) # 8. phase (0, 1, 2 or .) # 9. semicolon\-separated attributes (see below) # # Attributes required for # gene lines: # \- ID=gene: # \- biotype= # \- Name= [optional] # # transcript lines: # \- ID=transcript: # \- Parent=gene: # \- biotype= # # other lines (CDS, exon, five_prime_UTR, three_prime_UTR): # \- Parent=transcript: # # Supported biotypes: # \- see the function gff_parse_biotype() in bcftools/csq.c 1 ignored_field gene 21 2148 . \- . ID=gene:GeneId;biotype=protein_coding;Name=GeneName 1 ignored_field transcript 21 2148 . \- . ID=transcript:TranscriptId;Parent=gene:GeneId;biotype=protein_coding 1 ignored_field three_prime_UTR 21 2054 . \- . Parent=transcript:TranscriptId 1 ignored_field exon 21 2148 . \- . Parent=transcript:TranscriptId 1 ignored_field CDS 21 2148 . \- 1 Parent=transcript:TranscriptId 1 ignored_field five_prime_UTR 210 2148 . \- . Parent=transcript:TranscriptId .fam .fi .if n .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-l, \-\-local\-csq\fP .RS 4 switch off haplotype\-aware calling, run localized predictions considering only one VCF record at a time .RE .sp \fB\-n, \-\-ncsq\fP \fIINT\fP .RS 4 maximum number of per\-haplotype consequences to consider for each site. The INFO/BCSQ column includes all consequences, but only the first \fIINT\fP will be referenced by the FORMAT/BCSQ fields. The default value is 15 which corresponds to one 32\-bit integer per diploid sample, after accounting for values reserved by the BCF specification. Note that increasing the value leads to increased size of the output BCF. .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIt\fP|\fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP. In addition, a custom tab\-delimited plain text output can be printed (\fIt\fP). .RE .sp \fB\-p, \-\-phase\fP \fIa\fP|\fIm\fP|\fIr\fP|\fIR\fP|\fIs\fP .RS 4 how to handle unphased heterozygous genotypes: .sp \fIa\fP .RS 4 take GTs as is, create haplotypes regardless of phase (0/1 \(-> 0|1) .RE .sp \fIm\fP .RS 4 merge all GTs into a single haplotype (0/1 \(-> 1, 1/2 \(-> 1) .RE .sp \fIr\fP .RS 4 require phased GTs, throw an error on unphased heterozygous GTs .RE .sp \fIR\fP .RS 4 create non\-reference haplotypes if possible (0/1 \(-> 1|1, 1/2 \(-> 1|2) .RE .sp \fIs\fP .RS 4 skip unphased heterozygous GTs .RE .RE .sp \fB\-q, \-\-quiet\fP .RS 4 suppress warning messages .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 samples to include or "\-" to apply all variants and ignore samples .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-unify\-chr\-names\fP \fI0\fP|\fI1\fP .RS 4 Automatically detect and unify chromosome naming conventions in the GFF, fasta and VCF, such as "chrX" vs "X". The chromosome names in the output VCF will match that of the input VCF. The default is to attempt the automatic translation. .RE .sp \fB\-v, \-\-verbose\fP \fIINT\fP .RS 4 verbosity level (0\-2) .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .sp \fBExamples:\fP .sp .if n .RS 4 .nf .fam C # Basic usage bcftools csq \-f hs37d5.fa \-g Homo_sapiens.GRCh37.82.gff3.gz in.vcf \-Ob \-o out.bcf # Extract the translated haplotype consequences. The following TBCSQ variations # are recognised: # %TBCSQ .. print consequences in all haplotypes in separate columns # %TBCSQ{0} .. print the first haplotype only # %TBCSQ{1} .. print the second haplotype only # %TBCSQ{*} .. print a list of unique consequences present in either haplotype bcftools query \-f\*(Aq[%CHROM\(rst%POS\(rst%SAMPLE\(rst%TBCSQ\(rsn]\*(Aq out.bcf .fam .fi .if n .RE .sp \fBExamples of BCSQ annotation:\fP .sp .if n .RS 4 .nf .fam C # Two separate VCF records at positions 2:122106101 and 2:122106102 # change the same codon. This UV\-induced C>T dinucleotide mutation # has been annotated fully at the position 2:122106101 with # \- consequence type # \- gene name # \- ensembl transcript ID # \- coding strand (+ fwd, \- rev) # \- amino acid position (in the coding strand orientation) # \- list of corresponding VCF variants # The annotation at the second position gives the position of the full # annotation BCSQ=missense|CLASP1|ENST00000545861|\-|1174P>1174L|122106101G>A+122106102G>A BCSQ=@122106101 # A frame\-restoring combination of two frameshift insertions C>CG and T>TGG BCSQ=@46115084 BCSQ=inframe_insertion|COPZ2|ENST00000006101|\-|18AGRGP>18AQAGGP|46115072C>CG+46115084T>TGG # Stop gained variant BCSQ=stop_gained|C2orf83|ENST00000264387|\-|141W>141*|228476140C>T # The consequence type of a variant downstream from a stop are prefixed with * BCSQ=*missense|PER3|ENST00000361923|+|1028M>1028T|7890117T>C .fam .fi .if n .RE .sp \fBSupported consequence types\fP .sp .if n .RS 4 .nf .fam C 3_prime_utr 5_prime_utr coding_sequence feature_elongation frameshift inframe_altering inframe_deletion inframe_insertion intergenic intron missense non_coding splice_acceptor splice_donor splice_region start_lost start_retained stop_gained stop_lost stop_retained synonymous .fam .fi .if n .RE .sp See also \c .URL "https://ensembl.org/info/genome/variation/prediction/predicted_data.html" "" "" .SS "bcftools filter \fI[OPTIONS]\fP \fIFILE\fP" .sp Apply fixed\-threshold filters. .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-g, \-\-SnpGap\fP \fIINT\fP[:\*(Aqindel\*(Aq,\fImnp\fP,\fIbnd\fP,\fIother\fP,\fIoverlap\fP] .RS 4 filter SNPs within \fIINT\fP base pairs of an indel or other other variant type. The following example demonstrates the logic of \fB\-\-SnpGap\fP \fI3\fP applied on a deletion and an insertion: .RE .sp .if n .RS 4 .nf .fam C The SNPs at positions 1 and 7 are filtered, positions 0 and 8 are not: 0123456789 ref .G.GT..G.. del .A.G\-..A.. Here the positions 1 and 6 are filtered, 0 and 7 are not: 0123\-456789 ref .G.G\-..G.. ins .A.GT..A.. .fam .fi .if n .RE .sp \fB\-G, \-\-IndelGap\fP \fIINT\fP .RS 4 filter clusters of indels separated by \fIINT\fP or fewer base pairs allowing only one to pass. The following example demonstrates the logic of \fB\-\-IndelGap\fP \fI2\fP applied on a deletion and an insertion: .RE .sp .if n .RS 4 .nf .fam C The second indel is filtered: 012345678901 ref .GT.GT..GT.. del .G\-.G\-..G\-.. And similarly here, the second is filtered: 01 23 456 78 ref .A\-.A\-..A\-.. ins .AT.AT..AT.. .fam .fi .if n .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-\-mask\fP [^]\fIREGION\fP .RS 4 Soft filter regions, prepepend "^" to negate. Requires \fB\-s, \-\-soft\-filter\fP. .RE .sp \fB\-M, \-\-mask\-file\fP [^]\fIFILE\fP .RS 4 Soft filter regions listed in a file, "^" to negate. Requires \fB\-s, \-\-soft\-filter\fP. .RE .sp \fB\-\-mask\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 Same as \fB\-\-regions\-overlap\fP but for \fB\-\-mask/\-\-mask\-file\fP. See \fBCommon Options\fP. [1] .RE .sp \fB\-m, \-\-mode\fP [\fI+x\fP] .RS 4 define behaviour at sites with existing FILTER annotations. The default mode replaces existing filters of failed sites with a new FILTER string while leaving sites which pass untouched when non\-empty and setting to "PASS" when the FILTER string is absent. The "+" mode appends new FILTER strings of failed sites instead of replacing them. The "x" mode resets filters of sites which pass to "PASS". Modes "+" and "x" can both be set. .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-soft\-filter\fP \fISTRING\fP|\fI+\fP .RS 4 annotate FILTER column with \fISTRING\fP or, with \fI+\fP, a unique filter name generated by the program ("Filter%d"). Applies to records that do not meet filter expression. .RE .sp \fB\-S, \-\-set\-GTs\fP \fI.\fP|\fI0\fP .RS 4 set genotypes of failed samples to missing value (\fI.\fP) or reference allele (\fI0\fP) .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "bcftools gtcheck [\fIOPTIONS\fP] [\fB\-g\fP \fIgenotypes.vcf.gz\fP] \fIquery.vcf.gz\fP" .sp Checks sample identity. The program can operate in two modes. If the \fB\-g\fP option is given, the identity of samples from \fIquery.vcf.gz\fP is checked against the samples in the \fB\-g\fP file. Without the \fB\-g\fP option, multi\-sample cross\-check of samples in \fIquery.vcf.gz\fP is performed. .sp Note that the interpretation of the discordance score depends on the options provided (specifically \fB\-e\fP and \fB\-u\fP) and on the available annotations (FORMAT/PL vs FORMAT/GT). The discordance score can be interpreted as the number of mismatching genotypes only if GT\-vs\-GT matching is performed. .sp \fB\-\-distinctive\-sites\fP \fINUM[,MEM[,DIR]]\fP .RS 4 Find sites that can distinguish between at least NUM sample pairs. If the number is smaller or equal to 1, it is interpreted as the fraction of pairs. The optional MEM string sets the maximum memory used for in\-memory sorting and DIR is the temporary directory for external sorting. This option requires also \fB\-\-pairs\fP to be given. .RE .sp \fB\-\-dry\-run\fP .RS 4 Stop after first record to estimate required time. .RE .sp \fB\-e, \-\-exclude\fP [\fIqry\fP|\fIgt\fP]:\*(AqEXPRESSION\*(Aq .RS 4 Exclude sites from query file (\fIqry:\fP) or genotype file (\fIgt:\fP) for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-E, \-\-error\-probability\fP \fIINT\fP .RS 4 Interpret genotypes and genotype likelihoods probabilistically. The value of \fIINT\fP represents genotype quality when GT tag is used (e.g. Q=30 represents one error in 1,000 genotypes and Q=40 one error in 10,000 genotypes) and is ignored when PL tag is used (in that case an arbitrary non\-zero integer can be provided). \~ .br \~ .br If \fB\-E\fP is set to 0, the discordance score can be interpreted as the number of mismatching genotypes, but only in the GT\-vs\-GT matching mode. See the \fB\-u, \-\-use\fP option below for additional notes and caveats. \~ .br \~ .br If performance is an issue, set \fB\-E 0\fP for faster run times but less accurate results. \~ .br \~ .br Note that in previous versions of bcftools (\(lA1.18), this option used to be a smaller case \fB\-e\fP. It changed to make room for the filtering option \fB\-e, \-\-exclude\fP to stay consistent across other commands. .RE .sp \fB\-g, \-\-genotypes\fP \fIFILE\fP .RS 4 VCF/BCF file with reference genotypes to compare against .RE .sp \fB\-H, \-\-homs\-only\fP .RS 4 Homozygous genotypes only, useful with low coverage data (requires \fB\-g, \-\-genotypes\fP) .RE .sp \fB\-i, \-\-include\fP [\fIqry\fP|\fIgt\fP]:\*(AqEXPRESSION\*(Aq .RS 4 Include sites from query file (\fIqry:\fP) or genotype file (\fIgt:\fP) for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-\-n\-matches\fP \fIINT\fP .RS 4 Print only top INT matches for each sample, 0 for unlimited. Use negative value to sort by HWE probability rather than the number of discordant sites. Note that average score is used to determine the top matches, not absolute values. .RE .sp \fB\-\-no\-HWE\-prob\fP .RS 4 Disable calculation of HWE probability to reduce memory requirements with comparisons between very large number of sample pairs. .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 Write to \fIFILE\fP rather than to standard output, where it is written by default. .RE .sp \fB\-O, \-\-output\-type\fP \fIt\fP|\fIz\fP .RS 4 Write a plain (\fIt\fP) or compressed (\fIz\fP) text tab\-delimited output. .RE .sp \fB\-p, \-\-pairs\fP \fILIST\fP .RS 4 A comma\-separated list of sample pairs to compare. When the \fB\-g\fP option is given, the first sample must be from the query file, the second from the \fB\-g\fP file, third from the query file etc (qry,gt[,qry,gt..]). Without the \fB\-g\fP option, the pairs are created the same way but both samples are from the query file (qry,qry[,qry,qry..]) .RE .sp \fB\-P, \-\-pairs\-file\fP \fIFILE\fP .RS 4 A file with tab\-delimited sample pairs to compare. The first sample in the pair must come from the query file, the second from the genotypes file when \fB\-g\fP is given .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 Restrict to comma\-separated list of regions, see \fBCommon Options\fP .RE .sp *\-R, \-\-regions\-file\*(Aq \fIFILE\fP .RS 4 Restrict to regions listed in a file, see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP [\fIqry\fP|\fIgt\fP]:\*(AqLIST\*(Aq: List of query samples or \fB\-g\fP samples. If neither \fB\-s\fP nor \fB\-S\fP are given, all possible sample pair combinations are compared .sp \fB\-S, \-\-samples\-file\fP [\fIqry\fP|\fIgt\fP]:\*(AqFILE\*(Aq File with the query or \fB\-g\fP samples to compare. If neither \fB\-s\fP nor \fB\-S\fP are given, all possible sample pair combinations are compared .sp \fB\-t, \-\-targets\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-u, \-\-use\fP \fITAG1\fP[,\fITAG2\fP] .RS 4 specifies which tag to use in the query file (\fITAG1\fP) and the \fB\-g\fP (\fITAG2\fP) file. By default, the PL tag is used in the query file and, when available, the GT tags in the \fB\-g\fP file. \~ .br \~ .br Note that when the requested tag is not available, the program will attempt to use the other tag. The output includes the number of sites that were matched by the four possible modes (for example GT\-vs\-GT or GT\-vs\-PL). .RE .sp \fBExamples:\fP .sp .if n .RS 4 .nf .fam C # Check discordance of all samples from B against all samples in A bcftools gtcheck \-g A.bcf B.bcf # Limit comparisons to the given list of samples bcftools gtcheck \-s gt:a1,a2,a3 \-s qry:b1,b2 \-g A.bcf B.bcf # Compare only two pairs a1,b1 and a1,b2 bcftools gtcheck \-p a1,b1,a1,b2 \-g A.bcf B.bcf .fam .fi .if n .RE .SS "bcftools head [\fIOPTIONS\fP] [\fIFILE\fP]" .sp By default, prints all headers from the specified input file to standard output in VCF format. The input file may be in VCF or BCF format; if no \fIFILE\fP is specified, standard input will be read. With appropriate options, only some of the headers and/or additionally some of the variant records will be printed. .sp The \fBbcftools head\fP command outputs VCF headers almost exactly as they appear in the input file: it may add a \f(CR##FILTER=\fP header if not already present, but it never adds version or command line information itself. .SS "Options:" .sp \fB\-h, \-\-header\fP \fIINT\fP .RS 4 Display only the first \fIINT\fP header lines. By default, all header lines are displayed. .RE .sp \fB\-n, \-\-records\fP \fIINT\fP .RS 4 Also display the first \fIINT\fP variant records. By default, no variant records are displayed. .RE .sp \fB\-s, \-\-samples\fP \fIINT\fP .RS 4 Display the first \fIINT\fP variant records including the last #CHROM header line with samples. Running with \fB\-s 0\fP alone outputs the #CHROM header line only. Note that the list of samples, with each sample per line, can be obtained with \f(CRbcftools query\fP using the option \fB\-l, \-\-list\-samples\fP. .RE .SS "bcftools index [\fIOPTIONS\fP] \fIin.bcf\fP|\fIin.vcf.gz\fP" .sp Creates index for bgzip compressed VCF/BCF files for random access. CSI (coordinate\-sorted index) is created by default. The CSI format supports indexing of chromosomes up to length 2^31. TBI (tabix index) index files, which support chromosome lengths up to 2^29, can be created by using the \fI\-t/\-\-tbi\fP option or using the \fItabix\fP program packaged with htslib. When loading an index file, bcftools will try the CSI first and then the TBI. .SS "Indexing options:" .sp \fB\-c, \-\-csi\fP .RS 4 generate CSI\-format index for VCF/BCF files [default] .RE .sp \fB\-f, \-\-force\fP .RS 4 overwrite index if it already exists .RE .sp \fB\-m, \-\-min\-shift \fIINT\fP\fP .RS 4 set minimal interval size for CSI indices to 2^INT; default: 14 .RE .sp \fB\-o, \-\-output \fIFILE\fP\fP .RS 4 output file name. If not set, then the index will be created using the input file name plus a \fI.csi\fP or \fI.tbi\fP extension .RE .sp \fB\-t, \-\-tbi\fP .RS 4 generate TBI\-format index for VCF files .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .SS "Stats options:" .sp \fB\-a, \-\-all\fP .RS 4 Used in conjunction with \fB\-s, \-\-stats\fP, print per contig stats for all contigs, even those with zero records and those for which no stats are recorded in the index file (shown as \fI.\fP). .RE .sp \fB\-n, \-\-nrecords\fP .RS 4 print the number of records based on the CSI or TBI index files .RE .sp \fB\-s, \-\-stats\fP .RS 4 Print per contig stats based on the CSI or TBI index files. Output format is three tab\-delimited columns listing the contig name, contig length (\fI.\fP if unknown) and number of records for the contig. Contigs with zero records are not printed by default. .RE .SS "bcftools isec [\fIOPTIONS\fP] \fIA.vcf.gz\fP \fIB.vcf.gz\fP [...]" .sp Creates intersections, unions and complements of VCF files. Depending on the options, the program can output records from one (or more) files which have (or do not have) corresponding records with the same position in the other files. .sp \fB\-c, \-\-collapse\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIall\fP|\fIsome\fP|\fInone\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-C, \-\-complement\fP .RS 4 output positions present only in the first file but missing in the others .RE .sp \fB\-e, \-\-exclude\fP \fI\-\fP|\fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. If \fB\-e\fP (or \fB\-i\fP) appears only once, the same filtering expression will be applied to all input files. Otherwise, \fB\-e\fP or \fB\-i\fP must be given for each input file. To indicate that no filtering should be performed on a file, use "\-" in place of \fIEXPRESSION\fP, as shown in the example below. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-f, \-\-apply\-filters\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. See discussion of \fB\-e, \-\-exclude\fP above. .RE .sp \fB\-f, \-\-file\-list\fP \fIFILE\fP .RS 4 Read file names from \fIFILE\fP, one file name per line. .RE .sp \fB\-n, \-\-nfiles\fP [+\-=]\fIINT\fP|~\fIBITMAP\fP .RS 4 output positions present in this many (=), this many or more (+), this many or fewer (\-), or the exact same (~) files .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP. When several files are being output, their names are controlled via \fB\-p\fP instead. .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-p, \-\-prefix\fP \fIDIR\fP .RS 4 if given, subset each of the input files accordingly. See also \fB\-w\fP. .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-w, \-\-write\fP \fILIST\fP .RS 4 comma\-separated list of input files to output given as 1\-based indices. With \fB\-p\fP and no \fB\-w\fP, all files are written. .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and defaults to tbi for vcf.gz and csi for bcf. This is done automatically with the \fB\-p\fP option if the output format is compressed. .RE .SS "Examples:" .sp Create intersection and complements of two sets saving the output in dir/* .sp .if n .RS 4 .nf .fam C bcftools isec \-p dir A.vcf.gz B.vcf.gz .fam .fi .if n .RE .sp Filter sites in A (require INFO/MAF>=0.01) and B (require INFO/dbSNP) but not in C, and create an intersection, including only sites which appear in at least two of the files after filters have been applied .sp .if n .RS 4 .nf .fam C bcftools isec \-e\*(AqMAF<0.01\*(Aq \-i\*(AqdbSNP=1\*(Aq \-e\- A.vcf.gz B.vcf.gz C.vcf.gz \-n +2 \-p dir .fam .fi .if n .RE .sp Extract and write records from A shared by both A and B using exact allele match .sp .if n .RS 4 .nf .fam C bcftools isec \-p dir \-n=2 \-w1 A.vcf.gz B.vcf.gz .fam .fi .if n .RE .sp Extract records private to A or B comparing by position only .sp .if n .RS 4 .nf .fam C bcftools isec \-p dir \-n\-1 \-c all A.vcf.gz B.vcf.gz .fam .fi .if n .RE .sp Print a list of records which are present in A and B but not in C and D .sp .if n .RS 4 .nf .fam C bcftools isec \-n~1100 \-c all A.vcf.gz B.vcf.gz C.vcf.gz D.vcf.gz .fam .fi .if n .RE .SS "bcftools merge [\fIOPTIONS\fP] \fIA.vcf.gz\fP \fIB.vcf.gz\fP [...]" .sp Merge multiple VCF/BCF files from non\-overlapping sample sets to create one multi\-sample file. For example, when merging file \fIA.vcf.gz\fP containing samples \fIS1\fP, \fIS2\fP and \fIS3\fP and file \fIB.vcf.gz\fP containing samples \fIS3\fP and \fIS4\fP, the output file will contain five samples named \fIS1\fP, \fIS2\fP, \fIS3\fP, \fI2:S3\fP and \fIS4\fP. .sp Note that it is responsibility of the user to ensure that the sample names are unique across all files. If they are not, the program will exit with an error unless the option \fB\-\-force\-samples\fP is given. The sample names can be also given explicitly using the \fB\-\-print\-header\fP and \fB\-\-use\-header\fP options. .sp Note that only records from different files can be merged, never from the same file. For "vertical" merge take a look at \fBbcftools concat\fP or \fBbcftools norm \-m\fP instead. .sp \fB\-\-force\-no\-index\fP .RS 4 synonymous to \fB\-\-no\-index\fP .RE .sp \fB\-\-force\-samples\fP .RS 4 if the merged files contain duplicate samples names, proceed anyway. Duplicate sample names will be resolved by prepending the index of the file as it appeared on the command line to the conflicting sample name (see \fI2:S3\fP in the above example). .RE .sp \fB\-\-force\-single\fP .RS 4 run even if only one file is given on input .RE .sp \fB\-\-print\-header\fP .RS 4 print only merged header and exit .RE .sp \fB\-\-use\-header\fP \fIFILE\fP .RS 4 use the VCF header in the provided text \fIFILE\fP .RE .sp \fB\-0 \-\-missing\-to\-ref\fP .RS 4 assume genotypes at missing sites are 0/0 .RE .sp \fB\-f, \-\-apply\-filters\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-F, \-\-filter\-logic\fP \fIx\fP|\fI+\fP .RS 4 Set the output record to PASS if any of the inputs is PASS (\fIx\fP), or apply all filters (\fI+\fP), which is the default. .RE .sp \fB\-g, \-\-gvcf\fP \fI\-\fP|\fIFILE\fP .RS 4 merge gVCF blocks, INFO/END tag is expected. If the reference fasta file \fIFILE\fP is not given and the dash (\fI\-\fP) is given, unknown reference bases generated at gVCF block splits will be substituted with N\(cqs. The \fB\-\-gvcf\fP option uses the following default INFO rules: \fB\-i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max\fP and the following missing rules: \fB\-M PL:max,AD:0\fP. .RE .sp \fB\-i, \-\-info\-rules\fP \fI\-\fP|\fITAG:METHOD\fP[,...] .RS 4 Rules for merging INFO fields (scalars or vectors) or \fI\-\fP to disable the default rules. \fIMETHOD\fP is one of \fIsum\fP, \fIavg\fP, \fImin\fP, \fImax\fP, \fIjoin\fP. Default is \fIDP:sum,DP4:sum\fP if these fields exist in the input files. Fields with no specified rule will take the value from the first input file. The merged QUAL value is currently set to the maximum. This behaviour is not user controllable at the moment. .RE .sp \fB\-l, \-\-file\-list\fP \fIFILE\fP .RS 4 Read file names from \fIFILE\fP, one file name per line. .RE .sp \fB\-L, \-\-local\-alleles\fP \fIINT\fP .RS 4 Sites with many alternate alleles can require extremely large storage space which can exceed the 2GB size limit representable by BCF. This is caused by Number=G tags (such as FORMAT/PL) which store a value for each combination of reference and alternate alleles. The \fB\-L, \-\-local\-alleles\fP option allows replacement of such tags with a localized tag (FORMAT/LPL) which only includes a subset of alternate alleles relevant for that sample. A new FORMAT/LAA tag is added which lists 1\-based indices of the alternate alleles relevant (local) for the current sample. The number \fIINT\fP gives the maximum number of alternate alleles that can be included in the PL tag. The default value is 0 which disables the feature and outputs values for all alternate alleles. .RE .sp \fB\-m, \-\-merge\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIsnp\-ins\-del\fP|\fIall\fP|\fInone\fP|\fIid\fP[,\fI*\fP] .RS 4 The option controls what types of multiallelic records can be created. If single asterisk \fI*\fP is appended, the unobserved allele \fI<*>\fP or \fI\fP will be removed at variant sites; if two asterisks \fI**\fP are appended, the unobserved allele will be removed all sites. .RE .sp .if n .RS 4 .nf .fam C \-m none .. no new multiallelics, output multiple records instead \-m snps .. allow multiallelic SNP records \-m indels .. allow multiallelic indel records \-m both .. both SNP and indel records can be multiallelic \-m both,* .. same as above but remove <*> (or ) from variant sites \-m both,** .. same as above but remove <*> (or ) at all sites \-m all .. SNP records can be merged with indel records \-m snp\-ins\-del .. allow multiallelic SNVs, insertions, deletions, but don\*(Aqt mix them \-m id .. merge by ID .fam .fi .if n .RE .sp \fB\-M, \-\-missing\-rules\fP \fI\-\fP|\fITAG:METHOD\fP[,...] .RS 4 Rules for merging vector tags at multiallelic sites. When input files have different alternate alleles, vector fields pertaining to unobserved alleles are set to missing (\fI.\fP) by default. The \fIMETHOD\fP is one of \fI.\fP (the default, use missing values), \fINUMBER\fP (use a constant value, e.g. 0), \fImax\fP (the maximum value observed for other alleles in the sample). When \fB\-\-gvcf\fP option is set, the rule \fB\-M PL:max,AD:0\fP is implied. This can be overridden with providing \fB\-M \-\fP or \fB\-M PL:.,AD:.\fP. Note that if the unobserved allele is explicitly present as \fI<*>\fP or \fI\fP, then its corresponding value will be used regardless of \fB\-M\fP settings. .RE .sp \fB\-\-no\-index\fP .RS 4 the option allows files to be merged without indexing them first. In order for this option to work, the user must ensure that the input files have chromosomes in the same order and consistent with the order of sequences in the VCF header. .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "bcftools mpileup [\fIOPTIONS\fP] \fB\-f\fP \fIref.fa\fP \fIin.bam\fP [\fIin2.bam\fP [...]]" .sp Generate VCF or BCF containing genotype likelihoods for one or multiple alignment (BAM or CRAM) files. This is based on the original \fBsamtools mpileup\fP command (with the \fB\-v\fP or \fB\-g\fP options) producing genotype likelihoods in VCF or BCF format, but not the textual pileup output. The \fBmpileup\fP command was transferred to bcftools in order to avoid errors resulting from use of incompatible versions of samtools and bcftools when using in the mpileup+bcftools call pipeline. .sp Individuals are identified from the SM tags in the @RG header lines. Multiple individuals can be pooled in one alignment file, also one individual can be separated into multiple files. If sample identifiers are absent, each input file is regarded as one sample. .sp Note that there are two orthogonal ways to specify locations in the input file; via \fB\-r\fP \fIregion\fP and \fB\-t\fP \fIpositions\fP. The former uses (and requires) an index to do random access while the latter streams through the file contents filtering out the specified regions, requiring no index. The two may be used in conjunction. For example a BED file containing locations of genes in chromosome 20 could be specified using \fB\-r 20 \-t chr20.bed\fP, meaning that the index is used to find chromosome 20 and then it is filtered for the regions listed in the BED file. Also note that the \fB\-r\fP option can be much slower than \fB\-t\fP with many regions and can require more memory when multiple regions and many alignment files are processed. .SS "Input options" .sp \fB\-6, \-\-illumina1.3+\fP .RS 4 Assume the quality is in the Illumina 1.3+ encoding. .RE .sp \fB\-A, \-\-count\-orphans\fP .RS 4 Include anomalous read pairs in variant calling, i.e. reads with flag PAIRED but not PROPER_PAIR set. By default such reads are discarded. .RE .sp \fB\-b, \-\-bam\-list\fP \fIFILE\fP .RS 4 List of input alignment files, one file per line [null] .RE .sp \fB\-B, \-\-no\-BAQ\fP .RS 4 Disable probabilistic realignment for the computation of base alignment quality (BAQ). BAQ is the Phred\-scaled probability of a read base being misaligned. Applying this option greatly helps to reduce false SNPs caused by misalignments. .RE .sp \fB\-C, \-\-adjust\-MQ\fP \fIINT\fP .RS 4 Coefficient for downgrading mapping quality for reads containing excessive mismatches. Mismatches are counted as a proportion of the number of aligned bases ("M", "X" or "=" CIGAR operations), along with their quality, to derive an upper\-bound of the mapping quality. Original mapping qualities lower than this are left intact, while higher ones are capped at the new adjusted score. .sp The exact formula is complex and likely tuned to specific instruments and specific alignment tools, so this option is disabled by default (indicated as having a zero value). Variables in the formulae and their meaning are defined below. .sp .if n .RS 4 .nf .fam C Variable Meaning / formula M The number of matching CIGAR bases (operation "M", "X" or "="). X The number of substitutions with quality >= 13. SubQ The summed quality of substitution bases included in X, capped at a maximum of quality 33 per mismatching base. ClipQ The summed quality of soft\-clipped or hard\-clipped bases. This has no minimum or maximum quality threshold per base. For hard\-clipped bases the per\-base quality is taken as 13. T SubQ \- 10 * log10(M^X / X!) + ClipQ/5 Cap MAX(0, INT * sqrt((INT \- T) / INT)) .fam .fi .if n .RE .sp Some notes on the impact of this. .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} As the number of mismatches increases, the mapping quality cap reduces, eventually resulting in discarded alignments. .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} High quality mismatches reduces the cap faster than low quality mismatches. .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} The starting INT value also acts as a hard cap on mapping quality, even when zero mismatches are observed. .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} Indels have no impact on the mapping quality. .sp The intent of this option is to work around aligners that compute a mapping quality using a local alignment without having any regard to the degree of clipping required or consideration of potential contamination or large scale insertions with respect to the reference. A record may align uniquely and have no close second match, but having a high number of mismatches may still imply that the reference is not the correct site. .sp However we do not recommend use of this parameter unless you fully understand the impact of it and have determined that it is appropriate for your sequencing technology. .RE .RE .sp \fB\-D, \-\-full\-BAQ\fP .RS 4 Run the BAQ algorithm on all reads, not just those in problematic regions. This matches the behaviour for Bcftools 1.12 and earlier. .sp By default mpileup uses heuristics to decide when to apply the BAQ algorithm. Most sequences will not be BAQ adjusted, giving a CPU time closer to \-\-no\-BAQ, but it will still be applied in regions with suspected problematic alignments. This has been tested to work well on single sample data with even allele frequency, but the reliability is unknown for multi\-sample calling and for low allele frequency variants so full BAQ is still recommended in those scenarios. .RE .sp \fB\-d, \-\-max\-depth\fP \fIINT\fP .RS 4 At a position, read maximally \fIINT\fP reads per input file. Note that the original \fBsamtools mpileup\fP command had a minimum value of \fI8000/n\fP where \fIn\fP was the number of input files given to mpileup. This means that in \fBsamtools mpileup\fP the default was highly likely to be increased and the \fB\-d\fP parameter would have an effect only once above the cross\-sample minimum of 8000. This behavior was problematic when working with a combination of single\- and multi\-sample bams, therefore in \fBbcftools mpileup\fP the user is given the full control (and responsibility), and an informative message is printed instead [250] .RE .sp \fB\-E, \-\-redo\-BAQ\fP .RS 4 Recalculate BAQ on the fly, ignore existing BQ tags .RE .sp \fB\-f, \-\-fasta\-ref\fP \fIFILE\fP .RS 4 The \fBfaidx\fP\-indexed reference file in the FASTA format. The file can be optionally compressed by \fBbgzip\fP. Reference is required by default unless the \fB\-\-no\-reference\fP option is set [null] .RE .sp \fB\-\-no\-reference\fP .RS 4 Do not require the \fB\-\-fasta\-ref\fP option. .RE .sp \fB\-G, \-\-read\-groups\fP \fIFILE\fP .RS 4 list of read groups to include or exclude if prefixed with "^". One read group per line. This file can also be used to assign new sample names to read groups by giving the new sample name as a second white\-space\-separated field, like this: "read_group_id new_sample_name". If the read group name is not unique, also the bam file name can be included: "read_group_id file_name sample_name". If all reads from the alignment file should be treated as a single sample, the asterisk symbol can be used: "* file_name sample_name". Alignments without a read group ID can be matched with "?". \fBNOTE:\fP The meaning of \fBbcftools mpileup \-G\fP is the opposite of \fBsamtools mpileup \-G\fP. .RE .sp .if n .RS 4 .nf .fam C RG_ID_1 RG_ID_2 SAMPLE_A RG_ID_3 SAMPLE_A RG_ID_4 SAMPLE_B RG_ID_5 FILE_1.bam SAMPLE_A RG_ID_6 FILE_2.bam SAMPLE_A * FILE_3.bam SAMPLE_C ? FILE_3.bam SAMPLE_D .fam .fi .if n .RE .sp \fB\-\-indels\-2.0\fP .RS 4 A new EXPERIMENTAL indel calling model which aims to address some known deficiencies of the current indel calling algorithm. Specifically, it uses diploid reference consensus sequence. Note that in the current version it has the potential to increase sensitivity but at the cost of decreased specificity. Only works with short\-read sequencing technologies. .RE .sp \fB\-\-indels\-cns\fP .RS 4 Another EXPERIMENTAL indel calling method, predating indels\-2.0 in PR form, but merged more recently. It also uses a diploid reference consensus, but with added parameters and heuristics to optimise for a variety of sequencing platforms. This is usually faster and more accurate than the default caller and \-\-indels\-2.0, but has not been tested on non\-diploid samples and samples without approximately even allele frequency. .RE .sp \fB\-\-no\-indels\-cns\fP .RS 4 May be used to turn off \-\-indels\-cns mode when using one of the newer profiles that has this enabled by default. .RE .sp \fB\-q, \-min\-MQ\fP \fIINT\fP .RS 4 Minimum mapping quality for an alignment to be used [0] .RE .sp \fB\-Q, \-\-min\-BQ\fP \fIINT\fP .RS 4 Minimum base quality for a base to be considered [13] .RE .sp \fB\-\-max\-BQ\fP \fIINT\fP .RS 4 Caps the base quality to a maximum value [60]. This can be particularly useful on technologies that produce overly optimistic high qualities, leading to too many false positives or incorrect genotype assignments. .RE .sp \fB\-r, \-\-regions\fP \fICHR\fP|\fICHR:POS\fP|\fICHR:FROM\-TO\fP|\fICHR:FROM\-\fP[,...] .RS 4 Only generate mpileup output in given regions. Requires the alignment files to be indexed. If used in conjunction with \-l then considers the intersection; see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIFILE\fP .RS 4 As for \fB\-r, \-\-regions\fP, but regions read from FILE; see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-ignore\-RG\fP .RS 4 Ignore RG tags. Treat all reads in one alignment file as one sample. .RE .sp \fB\-\-ls, \-\-skip\-all\-set\fP .RS 4 Skip reads with all of the FLAG bits set [null] .RE .sp \fB\-\-ns, \-\-skip\-any\-set\fP .RS 4 Skip reads with any of the FLAG bits set. This option replaces and is synonymous to the deprecated \fB\-\-ff, \-\-excl\-flags\fP [UNMAP,SECONDARY,QCFAIL,DUP] .RE .sp \fB\-\-lu, \-\-skip\-all\-unset\fP .RS 4 Skip reads with all of the FLAG bits unset. This option replaces and is synonymous to the deprecated \fB\-\-rf, \-\-incl\-flags\fP [null] .RE .sp \fB\-\-nu, \-\-skip\-any\-unset\fP .RS 4 Skip reads with any of the FLAG bits unset [null] .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 list of sample names. See \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 file of sample names to include or exclude if prefixed with "^". One sample per line. This file can also be used to rename samples by giving the new sample name as a second white\-space\-separated column, like this: "old_name new_name". If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\(rs a\(rs good\(rs sample\(rs name". .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-x, \-\-ignore\-overlaps\fP .RS 4 Disable read\-pair overlap detection. .RE .sp \fB\-\-seed\fP \fIINT\fP .RS 4 Set the random number seed used when sub\-sampling deep regions [0]. .RE .SS "Output options" .sp \fB\-a, \-\-annotate\fP \fILIST\fP .RS 4 Comma\-separated list of FORMAT and INFO tags to output. (case\-insensitive, the "FORMAT/" prefix is optional, and use "?" to list available annotations on the command line) [null]: .RE .sp .if n .RS 4 .nf .fam C FORMAT/AD .. Allelic depth (Number=R,Type=Integer) FORMAT/ADF .. Allelic depths on the forward strand (Number=R,Type=Integer) FORMAT/ADR .. Allelic depths on the reverse strand (Number=R,Type=Integer) FORMAT/DP .. Number of high\-quality bases (Number=1,Type=Integer) FORMAT/SP .. Phred\-scaled strand bias P\-value (Number=1,Type=Integer) FORMAT/SCR .. Number of soft\-clipped reads (Number=1,Type=Integer) INFO/AD .. Total allelic depth (Number=R,Type=Integer) INFO/ADF .. Total allelic depths on the forward strand (Number=R,Type=Integer) INFO/ADR .. Total allelic depths on the reverse strand (Number=R,Type=Integer) INFO/SCR .. Number of soft\-clipped reads (Number=1,Type=Integer) FORMAT/DV .. Deprecated in favor of FORMAT/AD; Number of high\-quality non\-reference bases, (Number=1,Type=Integer) FORMAT/DP4 .. Deprecated in favor of FORMAT/ADF and FORMAT/ADR; Number of high\-quality ref\-forward, ref\-reverse, alt\-forward and alt\-reverse bases (Number=4,Type=Integer) FORMAT/DPR .. Deprecated in favor of FORMAT/AD; Number of high\-quality bases for each observed allele (Number=R,Type=Integer) INFO/DPR .. Deprecated in favor of INFO/AD; Number of high\-quality bases for each observed allele (Number=R,Type=Integer) .fam .fi .if n .RE .sp \fB\-g, \-\-gvcf\fP \fIINT\fP[,...] .RS 4 output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers. For example, passing \fI5,15\fP will group sites into two types of gVCF blocks, the first with minimum per\-sample DP from the interval [5,15) and the latter with minimum depth 15 or more. In this example, sites with minimum per\-sample depth less than 5 will be printed as separate records, outside of gVCF blocks. .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 Write output to \fIFILE\fP, rather than the default of standard output. (The same short option is used for both \fB\-\-open\-prob\fP and \fB\-\-output\fP. If \fB\-o\fP\*(Aqs argument contains any non\-digit characters other than a leading + or \- sign, it is interpreted as \fB\-\-output\fP. Usually the filename extension will take care of this, but to write to an entirely numeric filename use \fB\-o \&./123\fP or \fB\-\-output 123\fP.) .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-U, \-\-mwu\-u\fP .RS 4 The the previous Mann\-Whitney U test score from version 1.12 and earlier. This is a probability score, but importantly it folds probabilities above or below the desired score into the same P. The new Mann\-Whitney U test score is a "Z score", expressing the score as the number of standard deviations away from the mean (with zero being matching the mean). It keeps both positive and negative values. This can be important for some tests where errors are asymmetric. .sp .if n .RS 4 .nf .fam C This option changes the INFO field names produced back to the ones used by the earlier Bcftools releases. For excample BQBZ becomes BQB. .fam .fi .if n .RE .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "Options for SNP/INDEL genotype likelihood computation" .sp \fB\-X, \-\-config\fP \fISTR\fP .RS 4 Specify a platform specific configuration profile. Specifying the profile as "list" will list the available profile names and the parameters they change. There are profiles named after a release, which should be used if you wish to ensure forward compatibility of results. The non\-versioned names (eg "illumina") will always point to the most recent set of parameters for that instrument type. The current values are: .sp .if n .RS 4 .nf .fam C 1.12 \-Q13 \-h100 \-m1 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C bgi bgi\-1.20 \-\-indels\-cns \-B \-\-indel\-size 80 \-F0.1 \-\-indel\-bias 0.9 \-\-seqq\-offset 120 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C illumina\-1.18 [ default values ] .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C illumina illumina\-1.20 \-\-indels\-cns \-\-seqq\-offset 125 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C ont \-B \-Q5 \-\-max\-BQ 30 \-I .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C ont\-sup ont\-sup\-1.20 \-\-indels\-cns \-B \-Q1 \-\-max\-BQ 35 \-\-delta\-BQ 99 \-F0.2 \-o15 \-e1 \-h110 \-\-del\-bias 0.4 \-\-indel\-bias 0.7 \-\-poly\-mqual \-\-seqq\-offset 130 \-\-indel\-size 80 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C pacbio\-ccs\-1.18 \-D \-Q5 \-\-max\-BQ 50 \-F0.1 \-o25 \-e1 \-M99999 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C pacbio\-ccs pacbio\-ccs\-1.20 \-\-indels\-cns \-B \-Q5 \-\-max\-BQ 50 \-F0.1 \-o25 \-e1 \-h300 \-\-delta\-BQ 10 \-\-del\-bias 0.4 \-\-poly\-mqual \-\-indel\-bias 0.9 \-\-seqq\-offset 118 \-\-indel\-size 80 \-\-score\-vs\-ref 0.7 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C ultima ultima\-1.20 \-\-indels\-cns \-B \-Q1 \-\-max\-BQ 30 \-\-delta\-BQ 10 \-F0.15 \-o20 \-e10 \-h250 \-\-del\-bias 0.3 \-\-indel\-bias 0.7 \-\-poly\-mqual \-\-seqq\-offset 140 \-\-score\-vs\-ref 0.3 \-\-indel\-size 80 .fam .fi .if n .RE .RE .sp \fB\-\-ar, \-\-ambig\-reads\fP \fIdrop\fP|\fIincAD\fP|\fIincAD0\fP .RS 4 What to do with ambiguous indel reads that do not span an entire short tandem repeat region: discard ambiguous reads from calling and do not increment high\-quality AD depth counters (\fIdrop\fP), exclude from calling but increment AD counters proportionally (\fIincAD\fP), exclude from calling and increment the first value of the AD counter (\fIincAD0\fP) [\fIdrop\fP] .RE .sp \fB\-e, \-\-ext\-prob\fP \fIINT\fP .RS 4 Phred\-scaled gap extension sequencing error probability. Reducing \fIINT\fP leads to longer indels [20] .RE .sp \fB\-F, \-\-gap\-frac\fP \fIFLOAT\fP .RS 4 Minimum fraction of gapped reads [0.002] .RE .sp \fB\-h, \-\-tandem\-qual\fP \fIINT\fP .RS 4 Coefficient for modeling homopolymer errors. Given an \fIl\fP\-long homopolymer run, the sequencing error of an indel of size s is modeled as \fIINT\fP*s/l [500] Increasing this informs the caller that indels in long homopolymers are more likely genuine and less likely to be sequencing artifacts. Hence increasing tandem\-qual will have higher recall and lower precision. Bcftools 1.12 and earlier had a default of 100, which was tuned around more error prone instruments. Note changing this may have a minor impact on SNP calling too. For maximum SNP calling accuracy, it may be preferable to adjust this lower again, although this will adversely affect indels. .RE .sp \fB\-\-indel\-bias\fP \fIFLOAT\fP .RS 4 Skews the indel scores up or down, trading recall (low false\-negative) vs precision (low false\-positive) [1.0]. In Bcftools 1.12 and earlier this parameter didn\(cqt exist, but had an implied value of 1.0. If you are planning to do heavy filtering of variants, selecting the best quality ones only (favouring precision over recall), it is advisable to set this lower (such as 0.75) while higher depth samples or where you favour recall rates over precision may work better with a higher value such as 2.0. .RE .sp \fB\-\-del\-bias\fP \fIFLOAT\fP .RS 4 Skews the likelihood of deletions over insertions. Defaults to an even distribution value of 1.0. Lower values imply a higher rate of false positive deletions (meaning candidate deletions are less likely to be real). .RE .sp \fB\-\-indel\-size\fP \fIINT\fP .RS 4 Indel window size to use when assessing the quality of candidate indels. Note that although the window size approximately corresponds to the maximum indel size considered, it is not an exact threshold [110] .RE .sp \fB\-\-seqq\-offset\fP \fIINT\fP .RS 4 Tunes the importance of indel sequence quality per depth. The final "seqQ" quality used is "offset \- 5*MIN(depth,20)". [120] .RE .sp \fB\-\-poly\-mqual\fP .RS 4 Use the lowest quality value within a homopolymer run, instead of the quality immediately adjacent to the indel. This may be important for unclocked instruments, particularly ones with a flow chemistry where runs of bases of identical type are incorporated together. .RE .sp \fB\-I, \-\-skip\-indels\fP .RS 4 Do not perform INDEL calling .RE .sp \fB\-L, \-\-max\-idepth\fP \fIINT\fP .RS 4 Skip INDEL calling if the average per\-sample depth is above \fIINT\fP [250] .RE .sp \fB\-m, \-\-min\-ireads\fP \fIINT\fP .RS 4 Minimum number gapped reads for indel candidates \fIINT\fP [1] .RE .sp \fB\-M, \-\-max\-read\-len\fP \fIINT\fP .RS 4 The maximum read length permitted by the BAQ algorithm [500]. Variants are still called on longer reads, but they will not be passed through the BAQ method. This limit exists to prevent excessively long BAQ times and high memory usage. Note if partial BAQ is enabled with \fI\-D\fP then raising this parameter will likely not have a significant a CPU cost. .RE .sp \fB\-o, \-\-open\-prob\fP \fIINT\fP .RS 4 Phred\-scaled gap open sequencing error probability. Reducing \fIINT\fP leads to more indel calls. (The same short option is used for both \fB\-\-open\-prob\fP and \fB\-\-output\fP. When \-o\(cqs argument contains only an optional + or \- sign followed by the digits 0 to 9, it is interpreted as \fB\-\-open\-prob\fP.) [40] .RE .sp \fB\-p, \-\-per\-sample\-mF\fP .RS 4 Apply \fB\-m\fP and \fB\-F\fP thresholds per sample to increase sensitivity of calling. By default both options are applied to reads pooled from all samples. .RE .sp \fB\-P, \-\-platforms\fP \fISTR\fP .RS 4 Comma\-delimited list of platforms (determined by \fB@RG\-PL\fP) from which indel candidates are obtained. It is recommended to collect indel candidates from sequencing technologies that have low indel error rate such as ILLUMINA [all] .RE .SS "Examples:" .sp Call SNPs and short INDELs, then mark low quality sites and sites with the read depth exceeding a limit. (The read depth should be adjusted to about twice the average read depth as higher read depths usually indicate problematic regions which are often enriched for artefacts.) One may consider to add \fB\-C50\fP to mpileup if mapping quality is overestimated for reads containing excessive mismatches. Applying this option usually helps for BWA\-backtrack alignments, but may not other aligners. .sp .if n .RS 4 .nf .fam C bcftools mpileup \-Ou \-f ref.fa aln.bam | \(rs bcftools call \-Ou \-mv | \(rs bcftools filter \-s LowQual \-e \*(Aq%QUAL<20 || DP>100\*(Aq > var.flt.vcf .fam .fi .if n .RE .SS "bcftools norm [\fIOPTIONS\fP] \fIfile.vcf.gz\fP" .sp Left\-align and normalize indels, check if REF alleles match the reference, split multiallelic sites into multiple rows; recover multiallelics from multiple rows. Left\-alignment and normalization will only be applied if the \fB\-\-fasta\-ref\fP option is supplied. .sp \fB\-a, \-\-atomize\fP .RS 4 Decompose complex variants, e.g. split MNVs into consecutive SNVs. See also \fB\-\-atom\-overlaps\fP and \fB\-\-old\-rec\-tag\fP. .RE .sp \fB\-\-atom\-overlaps\fP \fI.\fP|\fI*\fP .RS 4 Alleles missing because of an overlapping variant can be set either to missing (.) or to the star alele (*), as recommended by the VCF specification. IMPORTANT: Note that asterisk is expaneded by shell and must be put in quotes or escaped by a backslash: .RE .sp .if n .RS 4 .nf .fam C # Before atomization: 100 CC C,GG 1/2 # After: # bcftools norm \-a \-\-atom\-overlaps . 100 C G ./1 100 CC C 1/. 101 C G ./1 # After: # bcftools norm \-a \-\-atom\-overlaps \*(Aq*\*(Aq # bcftools norm \-a \-\-atom\-overlaps \(rs* 100 C G,* 2/1 100 CC C,* 1/2 101 C G,* 2/1 .fam .fi .if n .RE .sp \fB\-c, \-\-check\-ref\fP \fIe\fP|\fIw\fP|\fIx\fP|\fIs\fP .RS 4 what to do when incorrect or missing REF allele is encountered: exit (\fIe\fP), warn (\fIw\fP), exclude (\fIx\fP), or set/fix (\fIs\fP) bad sites. The \fIw\fP option can be combined with \fIx\fP and \fIs\fP. Note that \fIs\fP can swap alleles and will update genotypes (GT) and AC counts, but will not attempt to fix PL or other fields. Also note, and this cannot be stressed enough, that \fIs\fP will NOT fix strand issues in your VCF, do NOT use it for that purpose!!! (Instead see .URL "http://samtools.github.io/bcftools/howtos/plugin.af\-dist.html" "" "" and \c .URL "http://samtools.github.io/bcftools/howtos/plugin.fixref.html" "" ".)" .RE .sp \fB\-d, \-\-rm\-dup\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIall\fP|\fIexact\fP .RS 4 If a record is present multiple times, output only the first instance. See also \fB\-\-collapse\fP in \fBCommon Options\fP. .RE .sp \fB\-D, \-\-remove\-duplicates\fP .RS 4 If a record is present in multiple files, output only the first instance. Alias for \fB\-d none\fP, deprecated. .RE .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 do not normalize input records for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. Note that duplicate removal ignores this option. .RE .sp \fB\-f, \-\-fasta\-ref\fP \fIFILE\fP .RS 4 reference sequence. Supplying this option will turn on left\-alignment and normalization, however, see also the \fB\-\-do\-not\-normalize\fP option below. .RE .sp \fB\-\-force\fP .RS 4 try to proceed with \fB\-m\-\fP even if malformed tags with incorrect number of fields are encountered, discarding such tags. (Experimental, use at your own risk.) .RE .sp \fB\-g, \-\-gff\-annot\fP \fIFILE\fP .RS 4 when a GFF file is provided, follow HGVS 3\(cqrule and right\-align variants in transcripts on the forward strand. In case of overlapping transcripts, the default mode is to left\-align the variant. For a description of the supported GFF3 file format see \fBbcftools csq\fP. .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 normalize only input records for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. Note that duplicate removal ignores this option. .RE .sp \fB\-\-keep\-sum\fP \fITAG\fP[,...] .RS 4 keep vector sum constant when splitting multiallelic sites. Only AD tag is currently supported. See also \c .URL "https://github.com/samtools/bcftools/issues/360" "" "" .RE .sp \fB\-m, \-\-multiallelics\fP \fB\-\fP|\fB+\fP[\fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIany\fP] .RS 4 split multiallelic sites into biallelic records (\fB\-\fP) or join biallelic sites into multiallelic records (\fB+\fP). An optional type string can follow which controls variant types which should be split or merged together: If only SNP records should be split or merged, specify \fIsnps\fP; if both SNPs and indels should be merged separately into two records, specify \fIboth\fP; if SNPs and indels should be merged into a single record, specify \fIany\fP. \~ .br \~ .br Note that multiallelic sites with both SNPs and indels will be split into biallelic sites with both \fB\-m \-snps\fP and \fB\-m \-indels\fP. .RE .sp \fB\-\-multi\-overlaps\fP \fI0\fP|\fI.\fP .RS 4 use the reference (\fI0\fP) or missing (\fI.\fP) allele for overlapping alleles after splitting multiallelic sites .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-N, \-\-do\-not\-normalize\fP .RS 4 the \fI\-c s\fP option can be used to fix or set the REF allele from the reference \fI\-f\fP. The \fI\-N\fP option will not turn on indel normalisation as the \fI\-f\fP option normally implies .RE .sp \fB\-\-old\-rec\-tag\fP \fISTR\fP .RS 4 Add INFO/STR annotation with the original record. The format of the annotation is CHROM|POS|REF|ALT|USED_ALT_IDX. .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-strict\-filter\fP .RS 4 when merging (\fI\-m+\fP), merged site is PASS only if all sites being merged PASS .RE .sp \fB\-S, \-\-sort\fP \fIpos\fP|\fIlex\fP .RS 4 when splitting sites or processing duplicates, sort records on output by POS only (\fIpos\fP, the default) or by POS and lexicographically by REF+ALT (\fIlex\fP) .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-v, \-\-verbose\fP \fIINT\fP .RS 4 verbosity level of GFF parsing (0\-2) .RE .sp \fB\-w, \-\-site\-win\fP \fIINT\fP .RS 4 maximum distance between two records to consider when locally sorting variants which changed position during the realignment .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "bcftools [plugin \fINAME\fP|+\fINAME\fP] \fI[OPTIONS]\fP \fIFILE\fP \(em \fI[PLUGIN OPTIONS]\fP" .sp A common framework for various utilities. The plugins can be used the same way as normal commands only their name is prefixed with "+". Most plugins accept two types of parameters: general options shared by all plugins followed by a separator, and a list of plugin\-specific options. There are some exceptions to this rule, some plugins do not accept the common options and implement their own parameters. Therefore please pay attention to the usage examples that each plugin comes with. .SS "VCF input options:" .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .SS "VCF output options:" .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "Plugin options:" .sp \fB\-h, \-\-help\fP .RS 4 list plugin\(cqs options .RE .sp \fB\-l, \-\-list\-plugins\fP .RS 4 List all available plugins. .sp By default, appropriate system directories are searched for installed plugins. You can override this by setting the BCFTOOLS_PLUGINS environment variable to a colon\-separated list of directories to search. If BCFTOOLS_PLUGINS begins with a colon, ends with a colon, or contains adjacent colons, the system directories are also searched at that position in the list of directories. .RE .sp \fB\-v, \-\-verbose\fP .RS 4 print debugging information to debug plugin failure .RE .sp \fB\-V, \-\-version\fP .RS 4 print version string and exit .RE .SS "List of plugins coming with the distribution:" .sp \fBad\-bias\fP .RS 4 find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD) .RE .sp \fBadd\-variantkey\fP .RS 4 add VariantKey INFO fields VKX and RSX .RE .sp \fBaf\-dist\fP .RS 4 collect AF deviation stats and GT probability distribution given AF and assuming HWE .RE .sp \fBallele\-length\fP .RS 4 count the frequency of the length of REF, ALT and REF+ALT .RE .sp \fBcheck\-ploidy\fP .RS 4 check if ploidy of samples is consistent for all sites .RE .sp \fBcheck\-sparsity\fP .RS 4 print samples without genotypes in a region or chromosome .RE .sp \fBcolor\-chrs\fP .RS 4 color shared chromosomal segments, requires trio VCF with phased GTs .RE .sp \fBcontrast\fP .RS 4 runs a basic association test, per\-site or in a region, and checks for novel alleles and genotypes in two groups of samples. Adds the following INFO annotations: .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} PASSOC .. Fisher\(cqs exact test probability of genotypic association (REF vs non\-REF allele) .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} FASSOC .. proportion of non\-REF allele in controls and cases .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} NASSOC .. number of control\-ref, control\-alt, case\-ref and case\-alt alleles .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} NOVELAL .. lists samples with a novel allele not observed in the control group .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} NOVELGT .. lists samples with a novel genotype not observed in the control group .RE .RE .sp \fBcounts\fP .RS 4 a minimal plugin which counts number of SNPs, Indels, and total number of sites. .RE .sp \fBdosage\fP .RS 4 print genotype dosage. By default the plugin searches for PL, GL and GT, in that order. .RE .sp \fBfill\-from\-fasta\fP .RS 4 fill INFO or REF field based on values in a fasta file .RE .sp \fBfill\-tags\fP .RS 4 set various INFO tags. The list of tags supported in this version: .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/AC Number:A Type:Integer .. Allele count in genotypes .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/AC_Hom Number:A Type:Integer .. Allele counts in homozygous genotypes .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/AC_Het Number:A Type:Integer .. Allele counts in heterozygous genotypes .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/AC_Hemi Number:A Type:Integer .. Allele counts in hemizygous genotypes .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/AF Number:A Type:Float .. Allele frequency .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/AN Number:1 Type:Integer .. Total number of alleles in called genotypes .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/ExcHet Number:A Type:Float .. Test excess heterozygosity; 1=good, 0=bad .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/END Number:1 Type:Integer .. End position of the variant .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/F_MISSING Number:1 Type:Float .. Fraction of missing genotypes .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/HWE Number:A Type:Float .. HWE test (PMID:15789306); 1=good, 0=bad .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/MAF Number:A Type:Float .. Minor Allele frequency .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/NS Number:1 Type:Integer .. Number of samples with data .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO/TYPE Number:. Type:String .. The record type (REF,SNP,MNP,INDEL,etc) .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} FORMAT/VAF Number:A Type:Float .. The fraction of reads with the alternate allele, requires FORMAT/AD or ADF+ADR .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} FORMAT/VAF1 Number:1 Type:Float .. The same as FORMAT/VAF but for all alternate alleles cumulatively .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} TAG=func(TAG) Number:1 Type:Integer .. Experimental support for user\-defined expressions such as "DP=sum(DP)" .RE .RE .sp \fBfixploidy\fP .RS 4 sets correct ploidy .RE .sp \fBfixref\fP .RS 4 determine and fix strand orientation .RE .sp \fBframeshifts\fP .RS 4 annotate frameshift indels .RE .sp \fBGTisec\fP .RS 4 count genotype intersections across all possible sample subsets in a vcf file .RE .sp \fBGTsubset\fP .RS 4 output only sites where the requested samples all exclusively share a genotype .RE .sp \fBguess\-ploidy\fP .RS 4 determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT) in the non\-PAR region of chrX. .RE .sp \fBgvcfz\fP .RS 4 compress gVCF file by resizing non\-variant blocks according to specified criteria .RE .sp \fBimpute\-info\fP .RS 4 add imputation information metrics to the INFO field based on selected FORMAT tags .RE .sp \fBindel\-stats\fP .RS 4 calculates per\-sample or de novo indels stats. The usage and format is similar to \fBsmpl\-stats\fP and \fBtrio\-stats\fP .RE .sp \fBisecGT\fP .RS 4 compare two files and set non\-identical genotypes to missing .RE .sp \fBmendelian\fP .RS 4 count Mendelian consistent / inconsistent genotypes (deprecated, use +mendelian2 instead) .RE .sp \fBmendelian2\fP .RS 4 count Mendelian consistent / inconsistent genotypes. .RE .sp \fBmissing2ref\fP .RS 4 sets missing genotypes ("./.") to ref allele ("0/0" or "0|0") .RE .sp \fBparental\-origin\fP .RS 4 determine parental origin of a CNV region .RE .sp \fBprune\fP .RS 4 prune sites by missingness, allele frequency or linkage disequilibrium. Alternatively, annotate sites with r2, Lewontin\(cqs D\*(Aq (PMID:19433632), Ragsdale\(cqs D (PMID:31697386). .RE .sp \fBremove\-overlaps\fP .RS 4 remove overlapping variants and duplicate sites .RE .sp \fBscatter\fP .RS 4 intended as an inverse to \f(CRbcftools concat\fP, scatter VCF by chunks or regions, creating multiple VCFs. .RE .sp \fBsetGT\fP .RS 4 general tool to set genotypes according to rules requested by the user .RE .sp \fBsmpl\-stats\fP .RS 4 calculates basic per\-sample stats. The usage and format is similar to \fBindel\-stats\fP and \fBtrio\-stats\fP. .RE .sp \fBsplit\fP .RS 4 split VCF by sample, creating single\- or multi\-sample VCFs .RE .sp \fBsplit\-vep\fP .RS 4 extract fields from structured annotations such as INFO/CSQ created by VEP or INFO/BCSQ created by bcftools/csq. These can be added as a new INFO field to the VCF or in a custom text format. See .URL "http://samtools.github.io/bcftools/howtos/plugin.split\-vep.html" "" "" for more. .RE .sp \fBtag2tag\fP .RS 4 Convert between similar tags, such as GL,PL,GP or QR,QA,QS or tags with localized alleles e.g. LPL,LAD. See \c .URL "http://samtools.github.io/bcftools/howtos/plugin.tag2tag.html" "" "" for more. .RE .sp \fBtrio\-dnm2\fP .RS 4 screen variants for possible de\-novo mutations in trios .RE .sp \fBtrio\-stats\fP .RS 4 calculate transmission rate in trio children. The usage and format is similar to \fBindel\-stats\fP and \fBsmpl\-stats\fP. .RE .sp \fBtrio\-switch\-rate\fP .RS 4 calculate phase switch rate in trio samples, children samples must have phased GTs .RE .sp \fBvariant\-distance\fP .RS 4 annotate sites with the distance to the nearest variant .RE .sp \fBvariantkey\-hex\fP .RS 4 generate unsorted VariantKey\-RSid index files in hexadecimal format .RE .SS "Examples:" .sp .if n .RS 4 .nf .fam C # List options common to all plugins bcftools plugin # List available plugins bcftools plugin \-l # Run a plugin bcftools plugin counts in.vcf # Run a plugin using the abbreviated "+" notation bcftools +counts in.vcf # Run a plugin from an explicit location bcftools +/path/to/counts.so in.vcf # The input VCF can be streamed just like in other commands cat in.vcf | bcftools +counts # Print usage information of plugin "dosage" bcftools +dosage \-h # Replace missing genotypes with 0/0 bcftools +missing2ref in.vcf # Replace missing genotypes with 0|0 bcftools +missing2ref in.vcf \-\- \-p .fam .fi .if n .RE .SS "Plugins troubleshooting:" .sp Things to check if your plugin does not show up in the \fBbcftools plugin \-l\fP output: .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} Run with the \fB\-v\fP option for verbose output: \fBbcftools plugin \-lv\fP .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} Does the environment variable BCFTOOLS_PLUGINS include the correct path? .RE .SS "Plugins API:" .sp .if n .RS 4 .nf .fam C // Short description used by \*(Aqbcftools plugin \-l\*(Aq const char *about(void); // Longer description used by \*(Aqbcftools +name \-h\*(Aq const char *usage(void); // Called once at startup, allows initialization of local variables. // Return 1 to suppress normal VCF/BCF header output, \-1 on critical // errors, 0 otherwise. int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr); // Called for each VCF record, return NULL to suppress the output bcf1_t *process(bcf1_t *rec); // Called after all lines have been processed to clean up void destroy(void); .fam .fi .if n .RE .SS "bcftools polysomy [\fIOPTIONS\fP] \fIfile.vcf.gz\fP" .sp Detect number of chromosomal copies in VCFs annotates with the Illumina\(cqs B\-allele frequency (BAF) values. Note that this command is not compiled in by default, see the section \fBOptional Compilation with GSL\fP in the INSTALL file for help. .SS "General options:" .sp \fB\-o, \-\-output\-dir\fP \fIpath\fP .RS 4 output directory .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-sample\fP \fIstring\fP .RS 4 sample name .RE .sp \fB\-t, \-\-targets\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-v, \-\-verbose\fP .RS 4 verbose debugging output which gives hints about the thresholds and decisions made by the program. Note that the exact output can change between versions. .RE .SS "Algorithm options:" .sp \fB\-b, \-\-peak\-size\fP \fIfloat\fP .RS 4 the minimum peak size considered as a good match can be from the interval [0,1] where larger is stricter .RE .sp \fB\-c, \-\-cn\-penalty\fP \fIfloat\fP .RS 4 a penalty for increasing copy number state. How this works: multiple peaks are always a better fit than a single peak, therefore the program prefers a single peak (normal copy number) unless the absolute deviation of the multiple peaks fit is significantly smaller. Here the meaning of "significant" is given by the \fIfloat\fP from the interval [0,1] where larger is stricter. .RE .sp \fB\-f, \-\-fit\-th\fP \fIfloat\fP .RS 4 threshold for goodness of fit (normalized absolute deviation), smaller is stricter .RE .sp \fB\-i, \-\-include\-aa\fP .RS 4 include also the AA peak in CN2 and CN3 evaluation. This usually requires increasing \fB\-f\fP. .RE .sp \fB\-m, \-\-min\-fraction\fP \fIfloat\fP .RS 4 minimum distinguishable fraction of aberrant cells. The experience shows that trustworthy are estimates of 20% and more. .RE .sp \fB\-p, \-\-peak\-symmetry\fP \fIfloat\fP .RS 4 a heuristics to filter failed fits where the expected peak symmetry is violated. The \fIfloat\fP is from the interval [0,1] and larger is stricter .RE .SS "bcftools query [\fIOPTIONS\fP] \fIfile.vcf.gz\fP [\fIfile.vcf.gz\fP [...]]" .sp Extracts fields from VCF or BCF files and outputs them in user\-defined format. .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-\-force\-samples\fP .RS 4 continue even when some samples requested via \fB\-s/\-S\fP do not exist .RE .sp \fB\-f, \-\-format\fP \fIFORMAT\fP .RS 4 learn by example, see below .RE .sp \fB\-F, \-\-print\-filtered\fP \fISTR\fP .RS 4 by default, samples failing \fB\-i/\-e\fP filtering expressions are suppressed from output when FORMAT fields are queried (for example \fI%CHROM %POS [ %GT]\fP). With \fB\-F\fP, such fields will be still printed but instead of their actual value, \fISTR\fP will be used. .RE .sp \fB\-H, \-\-print\-header\fP .RS 4 print header. By default, the header is printed with column indices, e.g. "#[1]CHROM". These can be suppressed by giving the option twice, "\f(CR\-HH\fP". .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-l, \-\-list\-samples\fP .RS 4 list sample names and exit .RE .sp \fB\-N, \-\-disable\-automatic\-newline\fP .RS 4 disable automatic addition of a missing newline character at the end of the formatting expression. By default, the program checks if the expression contains a newline and appends it if not, to prevent formatting the entire output into a single line by mistake. Note that versions prior to 1.18 had no automatic check and newline had to be included explicitly. .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-u, \-\-allow\-undef\-tags\fP .RS 4 do not throw an error if there are undefined tags in the format string, print "." instead .RE .sp \fB\-v, \-\-vcf\-list\fP \fIFILE\fP .RS 4 process multiple VCFs listed in the file .RE .SS "Format:" .sp .if n .RS 4 .nf .fam C %CHROM The CHROM column (similarly also other columns: POS, ID, REF, ALT, QUAL, FILTER) %END End position of the REF allele %END0 End position of the REF allele in 0\-based coordinates %FIRST_ALT Alias for %ALT{0} %FORMAT Prints all FORMAT fields or a subset of samples with \-s or \-S %GT Genotype (e.g. 0/1) %INFO Prints the whole INFO column %INFO/TAG Any tag in the INFO column %IUPACGT Genotype translated to IUPAC ambiguity codes (e.g. M instead of C/A) %LINE Prints the whole line %MASK Indicates presence of the site in other files (with multiple files) %N_PASS(expr) Number of samples that pass the filtering expression (see *<>*) %POS0 POS in 0\-based coordinates %PBINOM(TAG) Calculate phred\-scaled binomial probability, the allele index is determined from GT %SAMPLE Sample name %TAG{INT} Curly brackets to print a subfield (e.g. INFO/TAG{1}, the indexes are 0\-based) %TBCSQ Translated FORMAT/BCSQ. See the csq command above for explanation and examples. %TGT Translated genotype (e.g. C/A) %TYPE Variant type (REF, SNP, MNP, INDEL, BND, OTHER) %VKX VariantKey, biallelic hexadecimal encoding of CHROM,POS,REF,ALT (https://github.com/tecnickcom/variantkey) [] Format fields must be enclosed in brackets to loop over all samples \(rsn new line \(rst tab character .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C Everything else is printed verbatim. .fam .fi .if n .RE .SS "Examples:" .sp .if n .RS 4 .nf .fam C # Print chromosome, position, ref allele and the first alternate allele bcftools query \-f \*(Aq%CHROM %POS %REF %ALT{0}\(rsn\*(Aq file.vcf.gz .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Similar to above, but use tabs instead of spaces, add sample name and genotype bcftools query \-f \*(Aq%CHROM\(rst%POS\(rst%REF\(rst%ALT[\(rst%SAMPLE=%GT]\(rsn\*(Aq file.vcf.gz .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Print FORMAT/GT fields followed by FORMAT/GT fields bcftools query \-f \*(AqGQ:[ %GQ] \(rst GT:[ %GT]\(rsn\*(Aq file.vcf .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Make a BED file: chr, pos (0\-based), end pos (1\-based), id bcftools query \-f\*(Aq%CHROM\(rst%POS0\(rst%END\(rst%ID\(rsn\*(Aq file.bcf .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Print only samples with alternate (non\-reference) genotypes bcftools query \-f\*(Aq[%CHROM:%POS %SAMPLE %GT\(rsn]\*(Aq \-i\*(AqGT="alt"\*(Aq file.bcf .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Print all samples at sites with at least one alternate genotype bcftools view \-i\*(AqGT="alt"\*(Aq file.bcf \-Ou | bcftools query \-f\*(Aq[%CHROM:%POS %SAMPLE %GT\(rsn]\*(Aq .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Print phred\-scaled binomial probability from FORMAT/AD tag for all heterozygous genotypes bcftools query \-i\*(AqGT="het"\*(Aq \-f\*(Aq[%CHROM:%POS %SAMPLE %GT %PBINOM(AD)\(rsn]\*(Aq file.vcf .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Print the second value of AC field if bigger than 10. Note the (unfortunate) difference in # index subscript notation: formatting expressions (\-f) uses "{}" while filtering expressions # (\-i) use "[]". This is for historic reasons and backward\-compatibility. bcftools query \-f \*(Aq%AC{1}\(rsn\*(Aq \-i \*(AqAC[1]>10\*(Aq file.vcf.gz .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Print all samples at sites where at least one sample has DP=1 or DP=2. In the second case # print only samples with DP=1 or DP=2, the difference is in the logical operator used, || vs |. bcftools query \-f \*(Aq[%SAMPLE %GT %DP\(rsn]\*(Aq \-i \*(AqFMT/DP=1 || FMT/DP=2\*(Aq file.vcf bcftools query \-f \*(Aq[%SAMPLE %GT %DP\(rsn]\*(Aq \-i \*(AqFMT/DP=1 | FMT/DP=2\*(Aq file.vcf .fam .fi .if n .RE .SS "bcftools reheader [\fIOPTIONS\fP] \fIfile.vcf.gz\fP" .sp Modify header of VCF/BCF files, change sample names. .sp \fB\-f, \-\-fai\fP \fIFILE\fP .RS 4 add to the header contig names and their lengths from the provided fasta index file (.fai). Lengths of existing contig lines will be updated and contig lines not present in the fai file will be removed .RE .sp \fB\-h, \-\-header\fP \fIFILE\fP .RS 4 new VCF header .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fIFILE\fP .RS 4 new sample names, one name per line, in the same order as they appear in the VCF file. Alternatively, only samples which need to be renamed can be listed as "old_name new_name\(rsn" pairs separated by whitespaces, each on a separate line. If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\(rs a\(rs good\(rs sample\(rs name". .RE .sp \fB\-T, \-\-temp\-prefix\fP \fIPATH\fP .RS 4 this option is ignored, but left for compatibility with earlier versions of bcftools. .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .SS "bcftools roh [\fIOPTIONS\fP] \fIfile.vcf.gz\fP" .sp A program for detecting runs of homo/autozygosity. Only bi\-allelic sites are considered. .SS "The HMM model:" .sp .if n .RS 4 .nf .fam C Notation: D = Data, AZ = autozygosity, HW = Hardy\-Weinberg (non\-autozygosity), f = non\-ref allele frequency Emission probabilities: oAZ = P_i(D|AZ) = (1\-f)*P(D|RR) + f*P(D|AA) oHW = P_i(D|HW) = (1\-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1\-f)*P(D|RA) Transition probabilities: tAZ = P(AZ|HW) .. from HW to AZ, the \-a parameter tHW = P(HW|AZ) .. from AZ to HW, the \-H parameter ci = P_i(C) .. probability of cross\-over at site i, from genetic map AZi = P_i(AZ) .. probability of site i being AZ/non\-AZ, scaled so that AZi+HWi = 1 HWi = P_i(HW) P_{i+1}(AZ) = oAZ * max[(1 \- tAZ * ci) * AZ{i\-1} , tAZ * ci * (1\-AZ{i\-1})] P_{i+1}(HW) = oHW * max[(1 \- tHW * ci) * (1\-AZ{i\-1}) , tHW * ci * AZ{i\-1}] .fam .fi .if n .RE .SS "General Options:" .sp \fB\-\-AF\-dflt\fP \fIFLOAT\fP .RS 4 in case allele frequency is not known, use the \fIFLOAT\fP. By default, sites where allele frequency cannot be determined, or is 0, are skipped. .RE .sp \fB\-\-AF\-tag\fP \fITAG\fP .RS 4 use the specified INFO tag \fITAG\fP as an allele frequency estimate instead of the default AC and AN tags. Sites which do not have \fITAG\fP will be skipped. .RE .sp \fB\-\-AF\-file\fP \fIFILE\fP .RS 4 Read allele frequencies from a tab\-delimited file containing the columns: CHROM\(rstPOS\(rstREF,ALT\(rstAF. The file can be compressed with \fBbgzip\fP and indexed with tabix \-s1 \-b2 \-e2. Sites which are not present in the \fIFILE\fP or have different reference or alternate allele will be skipped. Note that such a file can be easily created from a VCF using: .RE .sp .if n .RS 4 .nf .fam C bcftools query \-f\*(Aq%CHROM\(rst%POS\(rst%REF,%ALT\(rst%INFO/TAG\(rsn\*(Aq file.vcf | bgzip \-c > freqs.tab.gz .fam .fi .if n .RE .sp \fB\-b, \-\-buffer\-size\fP \fIINT\fP[,\fIINT\fP] .RS 4 when the entire many\-sample file cannot fit into memory, a sliding buffer approach can be used. The first value is the number of sites to keep in memory. If negative, it is interpreted as the maximum memory to use, in MB. The second, optional, value sets the number of overlapping sites. The default overlap is set to roughly 1% of the buffer size. .RE .sp \fB\-e, \-\-estimate\-AF\fP \fIFILE\fP .RS 4 estimate the allele frequency by recalculating INFO/AC and INFO/AN on the fly, using the specified \fITAG\fP which can be either FORMAT/GT ("GT") or FORMAT/PL ("PL"). If \fITAG\fP is not given, "GT" is assumed. Either all samples ("\-") or samples listed in \fIFILE\fP will be included. For example, use "PL,\-" to estimate AF from FORMAT/PL of all samples. If neither \fB\-e\fP nor the other \fB\-\-AF\-...\fP options are given, the allele frequency is estimated from AC and AN counts which are already present in the INFO field. .RE .sp \fB\-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-G, \-\-GTs\-only\fP \fIFLOAT\fP .RS 4 use genotypes (FORMAT/GT fields) ignoring genotype likelihoods (FORMAT/PL), setting PL of unseen genotypes to \fIFLOAT\fP. Safe value to use is 30 to account for GT errors. .RE .sp \fB\-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-I, \-\-skip\-indels\fP .RS 4 skip indels as their genotypes are usually enriched for errors .RE .sp \fB\-m, \-\-genetic\-map\fP \fIFILE\fP .RS 4 genetic map in the format required also by IMPUTE2. Only the first and third column are used (position and Genetic_Map(cM)). The \fIFILE\fP can be a single file or a file mask, where string "{CHROM}" is replaced with chromosome name. .RE .sp \fB\-M, \-\-rec\-rate\fP \fIFLOAT\fP .RS 4 constant recombination rate per bp. In combination with \fB\-\-genetic\-map\fP, the \fB\-\-rec\-rate\fP parameter is interpreted differently, as \fIFLOAT\fP\-fold increase of transition probabilities, which allows the model to become more sensitive yet still account for recombination hotspots. Note that also the range of the values is therefore different in both cases: normally the parameter will be in the range (1e\-3,1e\-9) but with \fB\-\-genetic\-map\fP it will be in the range (10,1000). .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 Write output to the \fIFILE\fP, by default the output is printed on stdout .RE .sp \fB\-O, \-\-output\-type\fP \fIs\fP|\fIr\fP[\fIz\fP] .RS 4 Generate per\-site output (\fIs\fP) or per\-region output (\fIr\fP). By default both types are printed and the output is uncompressed. Add \fIz\fP for a compressed output. .RE .sp .if n .RS 4 .nf .fam C # Output fields: RG = predicted homo/autozygous regions \- Sample \- Chromosome \- Start \- End \- Length (bp) \- Number of markers \- Quality .. average phred score in the region from the forward\-backward algorithm ST = per\-site output showing: \- Sample \- Chromosome \- Position \- State .. predicted state from the Viterbi algorithm, 0 for normal (HW, Hardy\-Weinberg) or 1 for autozygous (AZ) \- Quality .. quality score from the forward\-backward algorithm .fam .fi .if n .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .SS "HMM Options:" .sp \fB\-a, \-\-hw\-to\-az\fP \fIFLOAT\fP .RS 4 P(AZ|HW) transition probability from AZ (autozygous) to HW (Hardy\-Weinberg) state .RE .sp \fB\-H, \-\-az\-to\-hw\fP \fIFLOAT\fP .RS 4 P(HW|AZ) transition probability from HW to AZ state .RE .sp \fB\-V, \-\-viterbi\-training\fP \fIFLOAT\fP .RS 4 estimate HMM parameters using Baum\-Welch algorithm, using the convergence threshold \fIFLOAT\fP, e.g. 1e\-10 (experimental) .RE .SS "bcftools sort [\fIOPTIONS\fP] file.bcf" .sp \fB\-m, \-\-max\-mem\fP \fIFLOAT\fP[\fIkMG\fP] .RS 4 Maximum memory to use. Approximate, affects the number of temporary files written to the disk. Note that if the command fails at this step because of too many open files, your system limit on the number of open files ("ulimit") may need to be increased. .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-temp\-dir\fP \fIDIR\fP .RS 4 Use this directory to store temporary files. If the last six characters of the string DIR are XXXXXX, then these are replaced with a string that makes the directory name unique. .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "bcftools stats [\fIOPTIONS\fP] \fIA.vcf.gz\fP [\fIB.vcf.gz\fP]" .sp Parses VCF or BCF and produces text file stats which is suitable for machine processing and can be plotted using \fBplot\-vcfstats\fP. When two files are given, the program generates separate stats for intersection and the complements. By default only sites are compared, \fB\-s\fP/\fB\-S\fP must given to include also sample columns. When one VCF file is specified on the command line, then stats by non\-reference allele frequency, depth distribution, stats by quality and per\-sample counts, singleton stats, etc. are printed. When two VCF files are given, then stats such as concordance (Genotype concordance by non\-reference allele frequency, Genotype concordance by sample, Non\-Reference Discordance) and correlation are also printed. Per\-site discordance (PSD) is also printed in \fB\-\-verbose\fP mode. .sp \fB\-\-af\-bins\fP \fILIST\fP|\fIFILE\fP .RS 4 comma separated list of allele frequency bins (e.g. 0.1,0.5,1) or a file listing the allele frequency bins one per line (e.g. 0.1\(rsn0.5\(rsn1) .RE .sp \fB\-\-af\-tag\fP \fITAG\fP .RS 4 allele frequency INFO tag to use for binning. By default the allele frequency is estimated from AC/AN, if available, or directly from the genotypes (GT) if not. .RE .sp \fB\-1, \-\-1st\-allele\-only\fP .RS 4 consider only the 1st alternate allele at multiallelic sites .RE .sp \fB\-c, \-\-collapse\fP \fIsnps\fP|\fIindels\fP|\fIboth\fP|\fIall\fP|\fIsome\fP|\fInone\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-d, \-\-depth\fP \fIINT\fP,\fIINT\fP,\fIINT\fP .RS 4 ranges of depth distribution: min, max, and size of the bin .RE .sp \fB\-\-debug\fP .RS 4 produce verbose per\-site and per\-sample output .RE .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-E, \-\-exons\fP \fIfile.gz\fP .RS 4 tab\-delimited file with exons for indel frameshifts statistics. The columns of the file are CHR, FROM, TO, with 1\-based, inclusive, positions. The file is BGZF\-compressed and indexed with tabix .RE .sp .if n .RS 4 .nf .fam C tabix \-s1 \-b2 \-e3 file.gz .fam .fi .if n .RE .sp \fB\-f, \-\-apply\-filters\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-F, \-\-fasta\-ref\fP \fIref.fa\fP .RS 4 faidx indexed reference sequence file to determine INDEL context .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include only sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-I, \-\-split\-by\-ID\fP .RS 4 collect stats separately for sites which have the ID column set ("known sites") or which do not have the ID column set ("novel sites"). .RE .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-u, \-\-user\-tstv\fP \fI\fP .RS 4 collect Ts/Tv stats for any tag using the given binning [0:1:100] .RE .sp \fB\-v, \-\-verbose\fP .RS 4 produce verbose per\-site and per\-sample output .RE .SS "bcftools view [\fIOPTIONS\fP] \fIfile.vcf.gz\fP [\fIREGION\fP [...]]" .sp View, subset and filter VCF or BCF files by position and filtering expression. Convert between VCF and BCF. Former \fBbcftools subset\fP. .SS "Output options" .sp \fB\-G, \-\-drop\-genotypes\fP .RS 4 drop individual genotype information (after subsetting if \fB\-s\fP option is set) .RE .sp \fB\-h, \-\-header\-only\fP .RS 4 output the VCF header only (see also \fBbcftools head\fP) .RE .sp \fB\-H, \-\-no\-header\fP .RS 4 suppress the header in VCF output .RE .sp \fB\-\-with\-header\fP .RS 4 output both VCF header and records (this is the default, but the option is useful for explicitness or to reset the effects of \fB\-h\fP or \fB\-H\fP) .RE .sp \fB\-l, \-\-compression\-level\fP [\fI0\-9\fP] .RS 4 compression level. 0 stands for uncompressed, 1 for best speed and 9 for best compression. .RE .sp \fB\-\-no\-version\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-O, \-\-output\-type\fP \fIb\fP|\fIu\fP|\fIz\fP|\fIv\fP[0\-9] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-o, \-\-output\fP \fIFILE\fP: output file name. If not present, the default is to print to standard output (stdout). .sp \fB\-r, \-\-regions\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-R, \-\-regions\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-regions\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-t, \-\-targets\fP \fIchr\fP|\fIchr:pos\fP|\fIchr:from\-to\fP|\fIchr:from\-\fP[,...] .RS 4 see \fBCommon Options\fP .RE .sp \fB\-T, \-\-targets\-file\fP \fIfile\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-targets\-overlap\fP \fI0\fP|\fI1\fP|\fI2\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-\-threads\fP \fIINT\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-W\fP[\fIFMT\fP]\fB, \-W\fP[=\fIFMT\fP]\fB, \-\-write\-index\fP[=\fIFMT\fP] .RS 4 Automatically index the output file. \fIFMT\fP is optional and can be one of "tbi" or "csi" depending on output file format. .RE .SS "Subset options:" .sp \fB\-A, \-\-trim\-unseen\-alleles\fP .RS 4 remove the unseen allele \fI<*>\fP or \fI\fP at variant sites when the option is given once (\-A) or at all sites when the options is given twice (\fI\-AA\fP). .RE .sp \fB\-a, \-\-trim\-alt\-alleles\fP .RS 4 remove alleles not seen in the genotype fields from the ALT column. Note that if no alternate allele remains after trimming, the record itself is not removed but ALT is set to ".". If the option \fB\-s\fP or \fB\-S\fP is given, removes alleles not seen in the subset. INFO and FORMAT tags declared as Type=A, G or R will be trimmed as well. .RE .sp \fB\-\-force\-samples\fP .RS 4 only warn about unknown subset samples .RE .sp \fB\-I, \-\-no\-update\fP .RS 4 do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN) .RE .sp \fB\-s, \-\-samples\fP \fILIST\fP .RS 4 see \fBCommon Options\fP. Note that it is possible to create multiple subsets simultaneously using the \fBsplit\fP plugin. .RE .sp \fB\-S, \-\-samples\-file\fP \fIFILE\fP .RS 4 see \fBCommon Options\fP. Note that it is possible to create multiple subsets simultaneously using the \fBsplit\fP plugin. .RE .SS "Filter options:" .sp Note that filter options below dealing with counting the number of alleles will, for speed, first check for the values of AC and AN in the INFO column to avoid parsing all the genotype (FORMAT/GT) fields in the VCF. This means that filters like \fI\-\-uncalled\fP, \-\-exclude\-uncalled\*(Aq, or \fI\-\-min\-af 0.1\fP will be calculated from INFO/AC and INFO/AN when available or FORMAT/GT otherwise. However, it will not attempt to use any other existing field, like INFO/AF for example. For that, use \fI\-\-exclude AF<0.1\fP instead. .sp Also note that one must be careful when sample subsetting and filtering is performed in a single command because the order of internal operations can influence the result. For example, the \fB\-i/\-e\fP filtering is performed before sample removal, but the \fB\-P\fP filtering is performed after, and some are inherently ambiguous, for example allele counts can be taken from the INFO column when present but calculated on the fly when absent. Therefore it is strongly recommended to spell out the required order explicitly by separating such commands into two steps. (Make sure to use the \fB\-O u\fP option when piping!) .sp \fB\-c, \-\-min\-ac\fP \fIINT\fP[\fI:nref\fP|\fI:alt1\fP|\fI:minor\fP|\fI:major\fP|:\*(Aqnonmajor\*(Aq] .RS 4 minimum allele count (INFO/AC) of sites to be printed. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fP, the default), 1st alternate (\fIalt1\fP), the least frequent (\fIminor\fP), the most frequent (\fImajor\fP) or sum of all but the most frequent (\fInonmajor\fP) alleles. .RE .sp \fB\-C, \-\-max\-ac\fP \fIINT\fP[\fI:nref\fP|\fI:alt1\fP|\fI:minor\fP|:\*(Aqmajor\*(Aq|:\*(Aqnonmajor\*(Aq] .RS 4 maximum allele count (INFO/AC) of sites to be printed. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fP, the default), 1st alternate (\fIalt1\fP), the least frequent (\fIminor\fP), the most frequent (\fImajor\fP) or sum of all but the most frequent (\fInonmajor\fP) alleles. .RE .sp \fB\-e, \-\-exclude\fP \fIEXPRESSION\fP .RS 4 exclude sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-f, \-\-apply\-filters\fP \fILIST\fP .RS 4 see \fBCommon Options\fP .RE .sp \fB\-g, \-\-genotype\fP [^][\fIhom\fP|\fIhet\fP|\fImiss\fP] .RS 4 include only sites with one or more homozygous (\fIhom\fP), heterozygous (\fIhet\fP) or missing (\fImiss\fP) genotypes. When prefixed with \fI^\fP, the logic is reversed; thus \fI^het\fP excludes sites with heterozygous genotypes. .RE .sp \fB\-i, \-\-include\fP \fIEXPRESSION\fP .RS 4 include sites for which \fIEXPRESSION\fP is true. For valid expressions see \fBEXPRESSIONS\fP. .RE .sp \fB\-k, \-\-known\fP .RS 4 print known sites only (ID column is not ".") .RE .sp \fB\-m, \-\-min\-alleles\fP \fIINT\fP .RS 4 print sites with at least \fIINT\fP alleles listed in REF and ALT columns .RE .sp \fB\-M, \-\-max\-alleles\fP \fIINT\fP .RS 4 print sites with at most \fIINT\fP alleles listed in REF and ALT columns. Use \fB\-m2 \-M2 \-v snps\fP to only view biallelic SNPs. .RE .sp \fB\-n, \-\-novel\fP .RS 4 print novel sites only (ID column is ".") .RE .sp \fB\-p, \-\-phased\fP .RS 4 print sites where all samples are phased. Haploid genotypes are considered phased. Missing genotypes considered unphased unless the phased bit is set. .RE .sp \fB\-P, \-\-exclude\-phased\fP .RS 4 exclude sites where all samples are phased .RE .sp \fB\-q, \-\-min\-af\fP \fIFLOAT\fP[\fI:nref\fP|\fI:alt1\fP|\fI:minor\fP|\fI:major\fP|\fI:nonmajor\fP] .RS 4 minimum allele frequency (INFO/AC / INFO/AN) of sites to be printed. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fP, the default), 1st alternate (\fIalt1\fP), the least frequent (\fIminor\fP), the most frequent (\fImajor\fP) or sum of all but the most frequent (\fInonmajor\fP) alleles. .RE .sp \fB\-Q, \-\-max\-af\fP \fIFLOAT\fP[\fI:nref\fP|\fI:alt1\fP|\fI:minor\fP|\fI:major\fP|\fI:nonmajor\fP] .RS 4 maximum allele frequency (INFO/AC / INFO/AN) of sites to be printed. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fP, the default), 1st alternate (\fIalt1\fP), the least frequent (\fIminor\fP), the most frequent (\fImajor\fP) or sum of all but the most frequent (\fInonmajor\fP) alleles. .RE .sp \fB\-u, \-\-uncalled\fP .RS 4 print sites without a called genotype, i.e. print sites with all genotypes missing. Note that the missingness is determined from INFO/AN and AC tags when available to avoid parsing sample fields. .RE .sp \fB\-U, \-\-exclude\-uncalled\fP .RS 4 exclude sites without a called genotype, i.e. print sites with at least one non\-missing genotype. Note that the missingness is determined from INFO/AN and AC tags when available to avoid parsing sample fields. .RE .sp \fB\-v, \-\-types\fP \fIsnps\fP|\fIindels\fP|\fImnps\fP|\fIother\fP .RS 4 comma\-separated list of variant types to select. Site is selected if any of the ALT alleles is of the type requested. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT. Use \fB\-\-include\fP to select based on INFO tags. .RE .sp \fB\-V, \-\-exclude\-types\fP \fIsnps\fP|\fIindels\fP|\fImnps\fP|\fIref\fP|\fIbnd\fP|\fIother\fP .RS 4 comma\-separated list of variant types to exclude. Site is excluded if any of the ALT alleles is of the type requested. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT. Use \fB\-\-exclude\fP to exclude based on INFO tags. .RE .sp \fB\-x, \-\-private\fP .RS 4 print sites where only the subset samples carry an non\-reference allele. Requires \fB\-\-samples\fP or \fB\-\-samples\-file\fP. .RE .sp \fB\-X, \-\-exclude\-private\fP .RS 4 exclude sites where only the subset samples carry an non\-reference allele .RE .SS "bcftools help [\fICOMMAND\fP] | bcftools \-\-help [\fICOMMAND\fP]" .sp Display a brief usage message listing the bcftools commands available. If the name of a command is also given, e.g., bcftools help view, the detailed usage message for that particular command is displayed. .SS "bcftools [\fI\-\-version\fP|\fI\-v\fP]" .sp Display the version numbers and copyright information for bcftools and the important libraries used by bcftools. .SS "bcftools [\fI\-\-version\-only\fP]" .sp Display the full bcftools version number in a machine\-readable format. .SH "SCRIPTS" .SS "gff2gff" .sp Attempts to fix a GFF file to be correctly parsed by \fBcsq\fP. .sp .if n .RS 4 .nf .fam C zcat in.gff.gz | gff2gff | gzip \-c > out.gff.gz .fam .fi .if n .RE .SS "plot\-vcfstats [\fIOPTIONS\fP] \fIfile.vchk\fP [...]" .sp Script for processing output of \fBbcftools stats\fP. It can merge results from multiple outputs (useful when running the stats for each chromosome separately), plots graphs and creates a PDF presentation. .sp \fB\-m, \-\-merge\fP .RS 4 Merge vcfstats files to STDOUT, skip plotting. .RE .sp \fB\-p, \-\-prefix\fP \fIDIR\fP .RS 4 The output directory. This directory will be created if it does not exist. .RE .sp \fB\-P, \-\-no\-PDF\fP .RS 4 Skip the PDF creation step. .RE .sp \fB\-r, \-\-rasterize\fP .RS 4 Rasterize PDF images for faster rendering. This is the default and the opposite of \fB\-v, \-\-vectors\fP. .RE .sp \fB\-s, \-\-sample\-names\fP .RS 4 Use sample names for xticks rather than numeric IDs. .RE .sp \fB\-t, \-\-title\fP \fISTRING\fP .RS 4 Identify files by these titles in plots. The option can be given multiple times, for each ID in the \fBbcftools stats\fP output. If not present, the script will use abbreviated source file names for the titles. .RE .sp \fB\-v, \-\-vectors\fP .RS 4 Generate vector graphics for PDF images, the opposite of \fB\-r, \-\-rasterize\fP. .RE .sp \fB\-T, \-\-main\-title\fP \fISTRING\fP .RS 4 Main title for the PDF. .RE .sp \fBExample:\fP .sp .if n .RS 4 .nf .fam C # Generate the stats bcftools stats \-s \- > file.vchk .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # Plot the stats plot\-vcfstats \-p outdir file.vchk .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C # The final looks can be customized by editing the generated # \*(Aqoutdir/plot.py\*(Aq script and re\-running manually cd outdir && python plot.py && pdflatex summary.tex .fam .fi .if n .RE .SH "FILTERING EXPRESSIONS" .sp These filtering expressions are accepted by most of the commands. .sp .B Valid expressions may contain: .br .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} numerical constants, string constants, file names (indicated by the prefix \fI@\fP) .sp .if n .RS 4 .nf .fam C 1, 1.0, 1e\-4 "String" @file_name .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} arithmetic operators (addition, multiplication, subtraction, division, modulo) .sp .if n .RS 4 .nf .fam C +, *, \-, /, % .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} comparison operators .sp .if n .RS 4 .nf .fam C == (same as =), >, >=, <=, <, != .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} regex operators "\(rs~" and its negation "!~". The expressions are case sensitive unless "/i" is added. .sp .if n .RS 4 .nf .fam C INFO/HAYSTACK ~ "needle" INFO/HAYSTACK ~ "NEEDless/i" .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} parentheses .sp .if n .RS 4 .nf .fam C (, ) .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} logical operators. See also the examples below and the \c .URL "http://samtools.github.io/bcftools/howtos/filtering.html" "filtering tutorial" about the distinction between "&&" vs "&" and "||" vs "|". .sp .if n .RS 4 .nf .fam C &&, &, ||, | .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} INFO tags, FORMAT tags, column names .sp .if n .RS 4 .nf .fam C INFO/DP or DP FORMAT/DV, FMT/DV, or DV FILTER, QUAL, ID, CHROM, POS, REF, ALT[0] .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} the FILTER column can be queried as follows: .sp .if n .RS 4 .nf .fam C FILTER="PASS" FILTER="." FILTER="A" .. exact match, for example "A;B" does not pass FILTER="A;B" .. exact match, "A;B" and "B;A" pass, everything else fails FILTER!="A" .. exact match, for example "A;B" does pass FILTER~"A" .. subset match, for example both "A" and "A;B" pass FILTER~"A;B" .. subset match, pass only if both "A" and "B" are present FILTER!~"A" .. complement match, for example both "A" and "A;B" fail FILTER!~"A;B" .. complement match, fail if both "A" and "B" are present .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} 1 (or 0) to test the presence (or absence) of a flag .sp .if n .RS 4 .nf .fam C FlagA=1 && FlagB=0 .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} "." to test missing values .sp .if n .RS 4 .nf .fam C DP=".", DP!=".", ALT="." .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} missing genotypes can be matched regardless of phase and ploidy (".|.", "./.", ".", "0|.") using these expressions .sp .if n .RS 4 .nf .fam C GT="mis", GT~"\(rs.", GT!~"\(rs." .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} missing genotypes can be matched including the phase and ploidy (".|.", "./.", ".") using these expressions .sp .if n .RS 4 .nf .fam C GT=".|.", GT="./.", GT="." .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} sample genotype: reference (haploid or diploid), alternate (hom or het, haploid or diploid), missing genotype, homozygous, heterozygous, haploid, ref\-ref hom, alt\-alt hom, ref\-alt het, alt\-alt het, haploid ref, haploid alt (case\-insensitive) .sp .if n .RS 4 .nf .fam C GT="ref" GT="alt" GT="mis" GT="hom" GT="het" GT="hap" GT="RR" GT="AA" GT="RA" or GT="AR" GT="Aa" or GT="aA" GT="R" GT="A" .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} TYPE for variant type in REF,ALT columns (indel,snp,mnp,ref,bnd,other,overlap, see \fBTERMINOLOGY\fP). Use the regex operator "\(rs~" to require at least one allele of the given type or the equal sign "=" to require that all alleles are of the given type. Compare .sp .if n .RS 4 .nf .fam C TYPE="snp" TYPE~"snp" TYPE!="snp" TYPE!~"snp" .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} array subscripts (0\-based), "*" for any element, "\-" to indicate a range. Note that for querying FORMAT vectors, the colon ":" can be used to select a sample and an element of the vector, as shown in the examples below. .sp .if n .RS 4 .nf .fam C INFO/AF[0] > 0.3 .. first AF value bigger than 0.3 FORMAT/AD[0:0] > 30 .. first AD value of the first sample bigger than 30 FORMAT/AD[0:1] .. first sample, second AD value FORMAT/AD[1:0] .. second sample, first AD value DP4[*] == 0 .. any DP4 value FORMAT/DP[0] > 30 .. DP of the first sample bigger than 30 FORMAT/DP[1\-3] > 10 .. samples 2\-4 FORMAT/DP[1\-] < 7 .. all samples but the first FORMAT/DP[0,2\-4] > 20 .. samples 1, 3\-5 FORMAT/AD[0:1] .. first sample, second AD field FORMAT/AD[0:*], AD[0:] or AD[0] .. first sample, any AD field FORMAT/AD[*:1] or AD[:1] .. any sample, second AD field (DP4[0]+DP4[1])/(DP4[2]+DP4[3]) > 0.3 CSQ[*] ~ "missense_variant.*deleterious" .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} in addition to array subscripts shown above, it is possible to subscript arrays of Number=R tags by alleles found in FORMAT/GT (starting with version 1.17). For example .sp .if n .RS 4 .nf .fam C FORMAT/AD[GT] > 10 .. require support of more than 10 reads for each allele FORMAT/AD[0:GT] > 10 .. same as above, but in the first sample sSUM(FORMAT/AD[GT]) > 20 .. require total sample depth bigger than 20 .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} with many samples it can be more practical to provide a file with sample names, one sample name per line .sp .if n .RS 4 .nf .fam C GT[@samples.txt]="het" & binom(AD)<0.01 .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} function on FORMAT tags (over samples) and INFO tags (over vector fields): maximum; minimum; arithmetic mean (AVG is synonymous with MEAN); median; standard deviation from mean; sum; string length; absolute value; number of elements: .sp .if n .RS 4 .nf .fam C MAX, MIN, AVG, MEAN, MEDIAN, STDEV, SUM, STRLEN, ABS, COUNT .fam .fi .if n .RE .sp Note that functions above evaluate to a single value across all samples and are intended to select sites, not samples, even when applied on FORMAT tags. However, when prefixed with SMPL_ (or "s" for brevity, e.g. SMPL_MAX or sMAX), they will evaluate to a vector of per\-sample values when applied on FORMAT tags: .sp .if n .RS 4 .nf .fam C SMPL_MAX, SMPL_MIN, SMPL_AVG, SMPL_MEAN, SMPL_MEDIAN, SMPL_STDEV, SMPL_SUM, sMAX, sMIN, sAVG, sMEAN, sMEDIAN, sSTDEV, sSUM .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} two\-tailed binomial test. Note that for N=0 the test evaluates to a missing value and when FORMAT/GT is used to determine the vector indices, it evaluates to 1 for homozygous genotypes. .sp .if n .RS 4 .nf .fam C binom(FMT/AD) .. GT can be used to determine the correct index binom(AD[0],AD[1]) .. or the fields can be given explicitly phred(binom()) .. the same as binom but phred\-scaled .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} variables calculated on the fly if not present: number of alternate alleles; number of samples; count of alternate alleles; minor allele count (similar to AC but is always smaller than 0.5); frequency of alternate alleles (AF=AC/AN); frequency of minor alleles (MAF=MAC/AN); number of alleles in called genotypes; number of samples with missing genotype; fraction of samples with missing genotype; indel length (deletions negative, insertions positive, balanced substitutions zero) .sp .if n .RS 4 .nf .fam C N_ALT, N_SAMPLES, AC, MAC, AF, MAF, AN, N_MISSING, F_MISSING, ILEN .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} the number (N_PASS) or fraction (F_PASS) of samples which pass the expression .sp .if n .RS 4 .nf .fam C N_PASS(GQ>90 & GT!="mis") > 90 F_PASS(GQ>90 & GT!="mis") > 0.9 .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} custom perl filtering. Note that this command is not compiled in by default, see the section \fBOptional Compilation with Perl\fP in the INSTALL file for help and misc/demo\-flt.pl for a working example. The demo defined the perl subroutine "severity" which can be invoked from the command line as follows: .sp .if n .RS 4 .nf .fam C perl:path/to/script.pl; perl.severity(INFO/CSQ) > 3 .fam .fi .if n .RE .RE .sp .B Notes: .br .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} String comparisons and regular expressions are case\-insensitive .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} Comma in strings is interpreted as a separator and when multiple values are compared, the OR logic is used. Consequently, the following two expressions are equivalent but not the third: .sp .if n .RS 4 .nf .fam C \-i \*(AqTAG="hello,world"\*(Aq \-i \*(AqTAG="hello" || TAG="world"\*(Aq \-i \*(AqTAG="hello" && TAG="world"\*(Aq .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} Variables and function names are case\-insensitive, but not tag names. For example, "qual" can be used instead of "QUAL", "strlen()" instead of "STRLEN()" , but not "dp" instead of "DP". .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} When querying multiple values, all elements are tested and the OR logic is used on the result. For example, when querying "TAG=1,2,3,4", it will be evaluated as follows: .sp .if n .RS 4 .nf .fam C \-i \*(AqTAG[*]=1\*(Aq .. true, the record will be printed \-i \*(AqTAG[*]!=1\*(Aq .. true \-e \*(AqTAG[*]=1\*(Aq .. false, the record will be discarded \-e \*(AqTAG[*]!=1\*(Aq .. false \-i \*(AqTAG[0]=1\*(Aq .. true \-i \*(AqTAG[0]!=1\*(Aq .. false \-e \*(AqTAG[0]=1\*(Aq .. false \-e \*(AqTAG[0]!=1\*(Aq .. true .fam .fi .if n .RE .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} When arithmetic operators are used on vectors A and B, the following logic is used to compute the resulting vector C: .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} C_i = A_i + B_i when length(A)==B(A) and sets length\(co=length(A) .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} C_i = A_i + B_0 when length(B)=1 and sets length\(co=length(A) .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} C_i = A_0 + B_i when length(A)=1 and sets length\(co=length(B) .RE .sp .RS 4 .ie n \{\ \h'-04'\(bu\h'+03'\c .\} .el \{\ . sp -1 . IP \(bu 2.3 .\} throw an error when length(A)!=length(B) AND length(A)!=1 AND length(B)!=1 .RE .RE .sp \fBExamples:\fP .sp .if n .RS 4 .nf .fam C MIN(DV)>5 .. selects the whole site, evaluates min across all values and samples .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C SMPL_MIN(DV)>5 .. selects matching samples, evaluates within samples .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C MIN(DV/DP)>0.3 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C MIN(DP)>10 & MIN(DV)>3 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C FMT/DP>10 & FMT/GQ>10 .. both conditions must be satisfied within one sample .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C FMT/DP>10 && FMT/GQ>10 .. the conditions can be satisfied in different samples .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C QUAL>10 | FMT/GQ>10 .. true for sites with QUAL>10 or a sample with GQ>10, but selects only samples with GQ>10 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C QUAL>10 || FMT/GQ>10 .. true for sites with QUAL>10 or a sample with GQ>10, plus selects all samples at such sites .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C TYPE="snp" && QUAL>=10 && (DP4[2]+DP4[3] > 2) .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C COUNT(GT="hom")=0 .. no homozygous genotypes at the site .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C AVG(GQ)>50 .. average (arithmetic mean) of genotype qualities bigger than 50 .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C ID=@file .. selects lines with ID present in the file .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C ID!=@~/file .. skip lines with ID present in the ~/file .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C INFO/TAG=@file .. selects lines with INFO/TAG value present in the file .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C MAF[0]<0.05 .. select rare variants at 5% cutoff .fam .fi .if n .RE .sp .if n .RS 4 .nf .fam C POS>=100 .. restrict your range query, e.g. 20:100\-200 to strictly sites with POS in that range. .fam .fi .if n .RE .sp \fBShell expansion:\fP .sp Note that expressions must often be quoted because some characters have special meaning in the shell. An example of expression enclosed in single quotes which cause that the whole expression is passed to the program as intended: .sp .if n .RS 4 .nf .fam C bcftools view \-i \*(Aq%ID!="." & MAF[0]<0.01\*(Aq .fam .fi .if n .RE .sp Please refer to the documentation of your shell for details. .SH "TERMINOLOGY" .sp The program and the documentation uses the following terminology, multiple terms can be used interchangeably for the same VCF record type .sp .if n .RS 4 .nf .fam C REF ALT \-\-\-\-\-\-\-\-\- C . .. reference allele / non\-variant site / ref\-only site C T .. SNP or SNV (single\-nucleotide polymorphism or variant), used interchangeably CC TT .. MNP (multi\-nucleotide polymorphism) CAAA C .. indel, deletion (regardless of length) C CAAA .. indel, insertion (regardless of length) C <*> .. gVCF block, the allele <*> is a placeholder for alternate allele possibly missed because of low coverage C .. synonymous to <*> C * .. overlapping deletion C .. symbolic allele, known also as \*(Aqother [than above]\*(Aq .fam .fi .if n .RE .SH "PERFORMANCE" .sp HTSlib was designed with BCF format in mind. When parsing VCF files, all records are internally converted into BCF representation. Simple operations, like removing a single column from a VCF file, can be therefore done much faster with standard UNIX commands, such as \fBawk\fP or \fBcut\fP. Therefore it is recommended to use BCF as input/output format whenever possible to avoid large overhead of the VCF \(-> BCF \(-> VCF conversion. .SH "BUGS" .sp Please report any bugs you encounter on the github website: \c .URL "http://github.com/samtools/bcftools" "" "" .SH "AUTHORS" .sp Heng Li from the Sanger Institute wrote the original C version of htslib, samtools and bcftools. Bob Handsaker from the Broad Institute implemented the BGZF library. Petr Danecek is maintaining and further developing bcftools, together with the rest of the \c .URL "https://www.sanger.ac.uk/tool/samtools\-bcftools\-htslib" "samtools team" "." Many other people contributed to the program and to the file format specifications, both directly and indirectly by providing patches, testing and reporting bugs. We thank them all. .SH "RESOURCES" .sp BCFtools GitHub website: \c .URL "http://github.com/samtools/bcftools" "" "" .sp Samtools GitHub website: \c .URL "http://github.com/samtools/samtools" "" "" .sp HTSlib GitHub website: \c .URL "http://github.com/samtools/htslib" "" "" .sp File format specifications: \c .URL "http://samtools.github.io/hts\-specs" "" "" .sp BCFtools documentation: \c .URL "http://samtools.github.io/bcftools" "" "" .sp BCFtools wiki page: \c .URL "https://github.com/samtools/bcftools/wiki" "" "" .SH "COPYING" .sp The MIT/Expat License or GPL License, see the LICENSE document for details. Copyright (c) Genome Research Ltd.bcftools-1.21/doc/bcftools.html000066400000000000000000007131001467060157400165320ustar00rootroot00000000000000 bcftools(1)

SYNOPSIS

bcftools [--version|--version-only] [--help] [COMMAND] [OPTIONS]

DESCRIPTION

BCFtools is a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed.

Most commands accept VCF, bgzipped VCF and BCF with filetype detected automatically even when streaming from a pipe. Indexed VCF and BCF will work in all situations. Un-indexed VCF and BCF and streams will work in most, but not all situations. In general, whenever multiple VCFs are read simultaneously, they must be indexed and therefore also compressed. (Note that files with non-standard index names can be accessed as e.g. "bcftools view -r X:2928329 file.vcf.gz##idx##non-standard-index-name".)

BCFtools is designed to work on a stream. It regards an input file "-" as the standard input (stdin) and outputs to the standard output (stdout). Several commands can thus be combined with Unix pipes.

VERSION

This manual page was last updated 2024-09-12 and refers to bcftools git version 1.21.

BCF1

The obsolete BCF1 format output by versions of samtools <= 0.1.19 is not compatible with this version of bcftools. To read BCF1 files one can use the view command from old versions of bcftools packaged with samtools versions <= 0.1.19 to convert to VCF, which can then be read by this version of bcftools.

    samtools-0.1.19/bcftools/bcftools view file.bcf1 | bcftools view

VARIANT CALLING

See bcftools call for variant calling from the output of the samtools mpileup command. In versions of samtools <= 0.1.19 calling was done with bcftools view. Users are now required to choose between the old samtools calling model (-c/--consensus-caller) and the new multiallelic calling model (-m/--multiallelic-caller). The multiallelic calling model is recommended for most tasks.

FILTERING EXPRESSIONS

See EXPRESSIONS

LIST OF COMMANDS

For a full list of available commands, run bcftools without arguments. For a full list of available options, run bcftools COMMAND without arguments.

  • annotate .. edit VCF files, add or remove annotations

  • call .. SNP/indel calling (former "view")

  • cnv .. Copy Number Variation caller

  • concat .. concatenate VCF/BCF files from the same set of samples

  • consensus .. create consensus sequence by applying VCF variants

  • convert .. convert VCF/BCF to other formats and back

  • csq .. haplotype aware consequence caller

  • filter .. filter VCF/BCF files using fixed thresholds

  • gtcheck .. check sample concordance, detect sample swaps and contamination

  • head .. view VCF/BCF file headers

  • index .. index VCF/BCF

  • isec .. intersections of VCF/BCF files

  • merge .. merge VCF/BCF files files from non-overlapping sample sets

  • mpileup .. multi-way pileup producing genotype likelihoods

  • norm .. normalize indels

  • plugin .. run user-defined plugin

  • polysomy .. detect contaminations and whole-chromosome aberrations

  • query .. transform VCF/BCF into user-defined formats

  • reheader .. modify VCF/BCF header, change sample names

  • roh .. identify runs of homo/auto-zygosity

  • sort .. sort VCF/BCF files

  • stats .. produce VCF/BCF stats (former vcfcheck)

  • view .. subset, filter and convert VCF and BCF files

LIST OF SCRIPTS

Some helper scripts are bundled with the bcftools code.

COMMANDS AND OPTIONS

Common Options

The following options are common to many bcftools commands. See usage for specific commands to see if they apply.

FILE

Files can be both VCF or BCF, uncompressed or BGZF-compressed. The file "-" is interpreted as standard input. Some tools may require tabix- or CSI-indexed files.

-c, --collapse snps|indels|both|all|some|none|id

Controls how to treat records with duplicate positions and defines compatible records across multiple input files. Here by "compatible" we mean records which should be considered as identical by the tools. For example, when performing line intersections, the desire may be to consider as identical all sites with matching positions (bcftools isec -c all), or only sites with matching variant type (bcftools isec -c snps  -c indels), or only sites with all alleles identical (bcftools isec -c none).

none

only records with identical REF and ALT alleles are compatible

some

only records where some subset of ALT alleles match are compatible

all

all records are compatible, regardless of whether the ALT alleles match or not. In the case of records with the same position, only the first will be considered and appear on output.

snps

any SNP records are compatible, regardless of whether the ALT alleles match or not. For duplicate positions, only the first SNP record will be considered and appear on output.

indels

all indel records are compatible, regardless of whether the REF and ALT alleles match or not. For duplicate positions, only the first indel record will be considered and appear on output.

both

abbreviation of "-c indels  -c snps"

id

only records with identical ID column are compatible. Supported by bcftools merge only.

-f, --apply-filters LIST

Skip sites where FILTER column does not contain any of the strings listed in LIST. For example, to include only sites which have no filters set, use -f .,PASS.

--no-version

Do not append version and command line information to the output VCF header.

-o, --output FILE

When output consists of a single stream, write it to FILE rather than to standard output, where it is written by default. The file type is determined automatically from the file name suffix and in case a conflicting -O option is given, the file name suffix takes precedence.

-O, --output-type b|u|z|v[0-9]

Output compressed BCF (b), uncompressed BCF (u), compressed VCF (z), uncompressed VCF (v). Use the -Ou option when piping between bcftools subcommands to speed up performance by removing unnecessary compression/decompression and VCF←→BCF conversion.   The compression level of the compressed formats (b and z) can be set by by appending a number between 0-9.

-r, --regions chr|chr:pos|chr:beg-end|chr:beg-[,…​]

Comma-separated list of regions, see also -R, --regions-file. Overlapping records are matched even when the starting coordinate is outside of the region, unlike the -t/-T options where only the POS coordinate is checked. Note that -r cannot be used in combination with -R.

-R, --regions-file FILE

Regions can be specified either on command line or in a VCF, BED, or tab-delimited file (the default). The columns of the tab-delimited file can contain either positions (two-column format: CHROM, POS) or intervals (three-column format: CHROM, BEG, END), but not both. Positions are 1-based and inclusive. The columns of the tab-delimited BED file are also CHROM, POS and END (trailing columns are ignored), but coordinates are 0-based, half-open. To indicate that a file be treated as BED rather than the 1-based tab-delimited file, the file must have the ".bed" or ".bed.gz" suffix (case-insensitive). Uncompressed files are stored in memory, while bgzip-compressed and tabix-indexed region files are streamed. Note that sequence names must match exactly, "chr20" is not the same as "20". Also note that chromosome ordering in FILE will be respected, the VCF will be processed in the order in which chromosomes first appear in FILE. However, within chromosomes, the VCF will always be processed in ascending genomic coordinate order no matter what order they appear in FILE. Note that overlapping regions in FILE can result in duplicated out of order positions in the output. This option requires indexed VCF/BCF files. Note that -R cannot be used in combination with -r.

--regions-overlap pos|record|variant|0|1|2

This option controls how overlapping records are determined: set to pos or 0 if the VCF record has to have POS inside a region (this corresponds to the default behavior of -t/-T); set to record or 1 if also overlapping records with POS outside a region should be included (this is the default behavior of -r/-R, and includes indels with POS at the end of a region, which are technically outside the region); or set to variant or 2 to include only true overlapping variation (compare the full VCF representation "TA>T-" vs the true sequence variation "A>-").

-s, --samples [^]LIST

Comma-separated list of samples to include or exclude if prefixed with "^." (Note that when multiple samples are to be excluded, the "^" prefix is still present only once, e.g. "^SAMPLE1,SAMPLE2".) The sample order is updated to reflect that given on the command line. Note that in general tags such as INFO/AC, INFO/AN, etc are not updated to correspond to the subset samples. bcftools view is the exception where some tags will be updated (unless the -I, --no-update option is used; see bcftools view documentation). To use updated tags for the subset in another command one can pipe from view into that command. For example:

    bcftools view -Ou -s sample1,sample2 file.vcf | bcftools query -f %INFO/AC\t%INFO/AN\n
-S, --samples-file [^]FILE

File of sample names to include or exclude if prefixed with "^". One sample per line. See also the note above for the -s, --samples option. The sample order is updated to reflect that given in the input file. The command bcftools call accepts an optional second column indicating ploidy (0, 1 or 2) or sex (as defined by --ploidy, for example "F" or "M"), for example:

    sample1    1
    sample2    2
    sample3    2

or

    sample1    M
    sample2    F
    sample3    F

If the second column is not present, the sex "F" is assumed. With bcftools call -C trio, PED file is expected. The program ignores the first column and the last indicates sex (1=male, 2=female), for example:

    ignored_column  daughterA fatherA  motherA  2
    ignored_column  sonB      fatherB  motherB  1
-t, --targets [^]chr|chr:pos|chr:from-to|chr:from-[,…​]

Similar as -r, --regions, but the next position is accessed by streaming the whole VCF/BCF rather than using the tbi/csi index. Both -r and -t options can be applied simultaneously: -r uses the index to jump to a region and -t discards positions which are not in the targets. Unlike -r, targets can be prefixed with "^" to request logical complement. For example, "^X,Y,MT" indicates that sequences X, Y and MT should be skipped. Yet another difference between the -t/-T and -r/-R is that -r/-R checks for proper overlaps and considers both POS and the end position of an indel, while -t/-T considers the POS coordinate only (by default; see also --regions-overlap and --targets-overlap). Note that -t cannot be used in combination with -T.

-T, --targets-file [^]FILE

Same -t, --targets, but reads regions from a file. Note that -T cannot be used in combination with -t.

With the call -C alleles command, third column of the targets file must be comma-separated list of alleles, starting with the reference allele. Note that the file must be compressed and indexed. Such a file can be easily created from a VCF using:

    bcftools query -f'%CHROM\t%POS\t%REF,%ALT\n' file.vcf | bgzip -c > als.tsv.gz && tabix -s1 -b2 -e2 als.tsv.gz
--targets-overlap pos|record|variant|0|1|2

Same as --regions-overlap but for -t/-T.

--threads INT

Use multithreading with INT worker threads. The option is currently used only for the compression of the output stream, only when --output-type is b or z. Default: 0.

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output files. FMT is optional and can be one of "tbi" or "csi" depending on output file format. Defaults to CSI unless specified otherwise. Can be used only for compressed BCF and VCF output.

bcftools annotate [OPTIONS] FILE

Add or remove annotations.

-a, --annotations file

Bgzip-compressed and tabix-indexed file with annotations. The file can be VCF, BED, or a tab-delimited file with mandatory columns CHROM, POS (or, alternatively, FROM and TO), optional columns REF and ALT, and arbitrary number of annotation columns. BED files are expected to have the ".bed" or ".bed.gz" suffix (case-insensitive), otherwise a tab-delimited file is assumed. Note that in case of tab-delimited file, the coordinates POS, FROM and TO are one-based and inclusive. When REF and ALT are present, only matching VCF records will be annotated. If the END coordinate is present in the annotation file and given on command line as "-c ~INFO/END", then VCF records will be matched also by the INFO/END coordinate. If ID is present in the annotation file and given as "-c ~ID", then VCF records will be matched also by the ID column.  
 
When multiple ALT alleles are present in the annotation file (given as comma-separated list of alleles), at least one must match one of the alleles in the corresponding VCF record. Similarly, at least one alternate allele from a multi-allelic VCF record must be present in the annotation file.  
 
Missing values can be added by providing "." in place of actual value and using the missing value modifier with -c, such as ".TAG".  
 
Note that flag types, such as "INFO/FLAG", can be annotated by including a field with the value "1" to set the flag, "0" to remove it, or "." to keep existing flags. See also -c, --columns and -h, --header-lines.

    # Sample annotation file with columns CHROM, POS, STRING_TAG, NUMERIC_TAG
    1  752566  SomeString      5
    1  798959  SomeOtherString 6
-c, --columns list

Comma-separated list of columns or tags to carry over from the annotation file (see also -a, --annotations). If the annotation file is not a VCF/BCF, list describes the columns of the annotation file and must include CHROM, POS (or, alternatively, FROM,TO or BEG,END), and optionally REF and ALT. Unused columns which should be ignored can be indicated by "-".  
 
If the annotation file is a VCF/BCF, only the edited columns/tags must be present and their order does not matter. The columns ID, QUAL, FILTER, INFO and FORMAT can be edited, where INFO tags can be written both as "INFO/TAG" or simply "TAG", and FORMAT tags can be written as "FORMAT/TAG" or "FMT/TAG". The imported VCF annotations can be renamed as "DST_TAG:=SRC_TAG" or "FMT/DST_TAG:=FMT/SRC_TAG".  
 
To carry over all INFO annotations, use "INFO". To add all INFO annotations except "TAG", use "^INFO/TAG". By default, existing values are replaced.  
 
By default, existing tags are overwritten unless the source value is a missing value (i.e. "."). If also missing values should be carried over (and overwrite existing tags), use ".TAG" instead of "TAG". To add annotations without overwriting existing values (that is, to add tags that are absent or to add values to existing tags with missing values), use "+TAG" instead of "TAG". These can be combined, for example ".+TAG" can be used to add TAG even if the source value is missing but only if TAG does not exist in the target file; existing tags will not be overwritten. To append to existing values (rather than replacing or leaving untouched), use "=TAG" (instead of "TAG" or "+TAG"). To replace only existing values without modifying missing annotations, use "-TAG". As a special case of this, if position needs to be replaced, mark the column with the new coordinate as "-POS". (Note that in previous releases this used to be "~POS", now deprecated.)  
 
To match the record also by ID or INFO/END, in addition to REF and ALT, use "~ID" or "~INFO/END". Note that this works only for ID and POS, for other fields see the description of -i below.  
 
If the annotation file is not a VCF/BCF, all new annotations must be defined via -h, --header-lines.  
 
See also the -l, --merge-logic option.  
 
Summary of -c, --columns:

    CHROM,POS,TAG       .. match by chromosome and position, transfer annotation from TAG
    CHROM,POS,-,TAG     .. same as above, but ignore the third column of the annotation file
    CHROM,BEG,END,TAG   .. match by region (BEG,END are synonymous to FROM,TO)
    CHROM,POS,REF,ALT   .. match by CHROM, POS, REF and ALT

    DST_TAG:=SRC_TAG    .. transfer the SRC_TAG using the new name DST_TAG
    INFO                .. transfer all INFO annotations
    ^INFO/TAG           .. transfer all INFO annotations except "TAG"

    TAG       .. add or overwrite existing target value if source is not "." and skip otherwise
    +TAG      .. add or overwrite existing target value only it is "."
    .TAG      .. add or overwrite existing target value even if source is "."
    .+TAG     .. add new but never overwrite existing tag, regardless of its value; can transfer "." if target does not exist
    -TAG      .. overwrite existing value, never add new if target does not exist
    =TAG      .. do not overwrite but append value to existing tags

    ~FIELD    .. use this column to match lines with -i/-e expression (see the description of -i below)
    ~ID       .. in addition to CHROM,POS,REF,ALT match by also ID
    ~INFO/END .. in addition to CHROM,POS,REF,ALT match by also INFO/END
-C, --columns-file file

Read the list of columns from a file (normally given via the -c, --columns option). "-" to skip a column of the annotation file. One column name per row, an additional space- or tab-separated field can be present to indicate the merge logic (normally given via the -l, --merge-logic option). This is useful when many annotations are added at once.

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS and the extension described in -i, --include below.

--force

continue even when parsing errors, such as undefined tags, are encountered. Note this can be an unsafe operation and can result in corrupted BCF files. If this option is used, make sure to sanity check the result thoroughly.

-h, --header-lines file

Lines to append to the VCF header, see also -c, --columns and -a, --annotations. For example:

    ##INFO=<ID=NUMERIC_TAG,Number=1,Type=Integer,Description="Example header line">
    ##INFO=<ID=STRING_TAG,Number=1,Type=String,Description="Yet another header line">
-I, --set-id [+]FORMAT

assign ID on the fly. The format is the same as in the query command (see below). By default all existing IDs are replaced. If the format string is preceded by "+", only missing IDs will be set. For example, one can use

    bcftools annotate --set-id +'%CHROM\_%POS\_%REF\_%FIRST_ALT' file.vcf
-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.  
 
Additionally, the command bcftools annotate supports expressions updated from the annotation file dynamically for each record:

    # The field 'STR' from the -a file is required to match INFO/TAG in VCF. In the first example
    # the alleles REF,ALT must match, in the second example they are ignored. The option -k is required
    # to output also records that are not annotated. The third example shows the same concept with
    # a numerical expression.
    bcftools annotate -a annots.tsv.gz -c CHROM,POS,REF,ALT,SCORE,~STR -i'TAG={STR}' -k input.vcf
    bcftools annotate -a annots.tsv.gz -c CHROM,POS,-,-,SCORE,~STR     -i'TAG={STR}' -k input.vcf
    bcftools annotate -a annots.tsv.gz -c CHROM,POS,-,-,SCORE,~INT     -i'TAG>{INT}' -k input.vcf
-k, --keep-sites

keep sites which do not pass -i and -e expressions instead of discarding them

-l, --merge-logic tag:first|append|append-missing|unique|sum|avg|min|max[,…​]

When multiple regions overlap a single record, this option defines how to treat multiple annotation values when setting tag in the destination file: use the first encountered value ignoring the rest (first); append allowing duplicates (append); append even if the appended value is missing, i.e. is a dot (append-missing); append discarding duplicate values (unique); sum the values (sum, numeric fields only); average the values (avg); use the minimum value (min) or the maximum (max). + Note that this option is intended for use with BED or TAB-delimited annotation files only. Moreover, it is effective only when either REF and ALT or BEG and END --columns are present . + Multiple rules can be given either as a comma-separated list or giving the option multiple times. This is an experimental feature.

-m, --mark-sites TAG

annotate sites which are present ("+") or absent ("-") in the -a file with a new INFO/TAG flag

--min-overlap ANN:'VCF'

minimum overlap required as a fraction of the variant in the annotation -a file (ANN), in the target VCF file (:VCF), or both for reciprocal overlap (ANN:VCF). By default overlaps of arbitrary length are sufficient. The option can be used only with the tab-delimited annotation -a file and with BEG and END columns present.

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

--pair-logic snps|indels|both|all|some|exact

Controls how to match records from the annotation file to the target VCF. Effective only when -a is a VCF or BCF. The option replaces the former uninuitive --collapse. See Common Options for more.

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

--rename-annots file

rename annotations according to the map in file, with "old_name new_name\n" pairs separated by whitespaces, each on a separate line. The old name must be prefixed with the annotation type: INFO, FORMAT, or FILTER.

--rename-chrs file

rename chromosomes according to the map in file, with "old_name new_name\n" pairs separated by whitespaces, each on a separate line.

-s, --samples [^]LIST

subset of samples to annotate, see also Common Options

-S, --samples-file FILE

subset of samples to annotate. If the samples are named differently in the target VCF and the -a, --annotations VCF, the name mapping can be given as "src_name dst_name\n", separated by whitespaces, each pair on a separate line.

--single-overlaps

use this option to keep memory requirements low with very large annotation files. Note, however, that this comes at a cost, only single overlapping intervals are considered in this mode. This was the default mode until the commit af6f0c9 (Feb 24 2019).

--threads INT

see Common Options

-x, --remove list

List of annotations to remove. Use "FILTER" to remove all filters or "FILTER/SomeFilter" to remove a specific filter. Similarly, "INFO" can be used to remove all INFO tags and "FORMAT" to remove all FORMAT tags except GT. To remove all INFO tags except "FOO" and "BAR", use "^INFO/FOO,INFO/BAR" (and similarly for FORMAT and FILTER). "INFO" can be abbreviated to "INF" and "FORMAT" to "FMT".

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

Examples:

    # Remove three fields
    bcftools annotate -x ID,INFO/DP,FORMAT/DP file.vcf.gz

    # Remove all INFO fields and all FORMAT fields except for GT and PL
    bcftools annotate -x INFO,^FORMAT/GT,FORMAT/PL file.vcf

    # Add ID, QUAL and INFO/TAG, not replacing TAG if already present
    bcftools annotate -a src.bcf -c ID,QUAL,+TAG dst.bcf

    # Carry over all INFO and FORMAT annotations except FORMAT/GT
    bcftools annotate -a src.bcf -c INFO,^FORMAT/GT dst.bcf

    # Annotate from a tab-delimited file with six columns (the fifth is ignored),
    # first indexing with tabix. The coordinates are 1-based.
    tabix -s1 -b2 -e2 annots.tab.gz
    bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,POS,REF,ALT,-,TAG file.vcf

    # Annotate from a tab-delimited file with regions (1-based coordinates, inclusive)
    tabix -s1 -b2 -e3 annots.tab.gz
    bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,FROM,TO,TAG input.vcf

    # Annotate from a bed file (0-based coordinates, half-closed, half-open intervals)
    bcftools annotate -a annots.bed.gz -h annots.hdr -c CHROM,FROM,TO,TAG input.vcf

    # Transfer the INFO/END tag, matching by POS,REF,ALT and ID. This example assumes
    # that INFO/END is already present in the VCF header.
    bcftools annotate -a annots.tab.gz  -c CHROM,POS,~ID,REF,ALT,INFO/END input.vcf

    # For (many) more examples see http://samtools.github.io/bcftools/howtos/annotate.html

bcftools call [OPTIONS] FILE

This command replaces the former bcftools view caller. Some of the original functionality has been temporarily lost in the process of transition under htslib, but will be added back on popular demand. The original calling model can be invoked with the -c option.

File format options:

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

--ploidy ASSEMBLY[?]

predefined ploidy, use list (or any other unused word) to print a list of all predefined assemblies. Append a question mark to print the actual definition. See also --ploidy-file.

--ploidy-file FILE

ploidy definition given as a space/tab-delimited list of CHROM, FROM, TO, SEX, PLOIDY. The SEX codes are arbitrary and correspond to the ones used by --samples-file. The default ploidy can be given using the starred records (see below), unlisted regions have ploidy 2. The default ploidy definition is

    X 1 60000 M 1
    X 2699521 154931043 M 1
    Y 1 59373566 M 1
    Y 1 59373566 F 0
    MT 1 16569 M 1
    MT 1 16569 F 1
    *  * *     M 2
    *  * *     F 2
-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples LIST

see Common Options

-S, --samples-file FILE

see Common Options

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

--threads INT

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

Input/output options:

-A, --keep-alts

output all alternate alleles present in the alignments even if they do not appear in any of the genotypes

-*, --keep-unseen-allele

keep the unobserved allele <*> or <NON_REF>, useful mainly for gVCF output

-f, --format-fields list

comma-separated list of FORMAT fields to output for each sample. Currently GQ and GP fields are supported. For convenience, the fields can be given as lower case letters. Prefixed with "^" indicates a request for tag removal of auxiliary tags useful only for calling.

-F, --prior-freqs AN,AC

take advantage of prior knowledge of population allele frequencies. The workflow looks like this:

    # Extract AN,AC values from an existing VCF, such 1000Genomes
    bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' 1000Genomes.bcf | bgzip -c > AFs.tab.gz

    # If the tags AN,AC are not already present, use the +fill-tags plugin
    bcftools +fill-tags 1000Genomes.bcf | bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' | bgzip -c > AFs.tab.gz
    tabix -s1 -b2 -e2 AFs.tab.gz

    # Create a VCF header description, here we name the tags REF_AN,REF_AC
    cat AFs.hdr
    ##INFO=<ID=REF_AN,Number=1,Type=Integer,Description="Total number of alleles in reference genotypes">
    ##INFO=<ID=REF_AC,Number=A,Type=Integer,Description="Allele count in reference genotypes for each ALT allele">

    # Now before calling, stream the raw mpileup output through `bcftools annotate` to add the frequencies
    bcftools mpileup [...] -Ou | bcftools annotate -a AFs.tab.gz -h AFs.hdr -c CHROM,POS,REF,ALT,REF_AN,REF_AC -Ou | bcftools call -mv -F REF_AN,REF_AC [...]
-G, --group-samples FILE|-

by default, all samples are assumed to come from a single population. This option groups samples into populations and apply the HWE assumption within but not across the populations. FILE is a tab-delimited text file with sample names in the first column and group names in the second column. If - is given instead, no HWE assumption is made at all and single-sample calling is performed. (Note that in low coverage data this inflates the rate of false positives.) The -G option requires the presence of per-sample FORMAT/QS or FORMAT/AD tag generated with bcftools mpileup -a QS (or -a AD).

-g, --gvcf INT[,…​]

output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers. For example, passing 5,15 will group sites into two types of gVCF blocks, the first with minimum per-sample DP from the interval [5,15) and the latter with minimum depth 15 or more. In this example, sites with minimum per-sample depth less than 5 will be printed as separate records, outside of gVCF blocks.

-i, --insert-missed INT

output also sites missed by mpileup but present in -T, --targets-file.

-M, --keep-masked-ref

output sites where REF allele is N

-V, --skip-variants snps|indels

skip indel/SNP sites

-v, --variants-only

output variant sites only

Consensus/variant calling options:

-c, --consensus-caller

the original samtools/bcftools calling method (conflicts with -m)

-C, --constrain alleles|trio
alleles

call genotypes given alleles. See also -T, --targets-file.

trio

call genotypes given the father-mother-child constraint. See also -s, --samples and -n, --novel-rate.

-m, --multiallelic-caller

alternative model for multiallelic and rare-variant calling designed to overcome known limitations in -c calling model (conflicts with -c)

-n, --novel-rate float[,…​]

likelihood of novel mutation for constrained -C trio calling. The trio genotype calling maximizes likelihood of a particular combination of genotypes for father, mother and the child P(F=i,M=j,C=k) = P(unconstrained) * Pn + P(constrained) * (1-Pn). By providing three values, the mutation rate Pn is set explicitly for SNPs, deletions and insertions, respectively. If two values are given, the first is interpreted as the mutation rate of SNPs and the second is used to calculate the mutation rate of indels according to their length as Pn=float*exp(-a-b*len), where a=22.8689, b=0.2994 for insertions and a=21.9313, b=0.2856 for deletions [pubmed:23975140]. If only one value is given, the same mutation rate Pn is used for SNPs and indels.

-p, --pval-threshold float

with -c, accept variant if P(ref|D) < float.

-P, --prior float

expected substitution rate, or 0 to disable the prior. Only with -m.

-t, --targets file|chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-X, --chromosome-X

haploid output for male samples (requires PED file with -s)

-Y, --chromosome-Y

haploid output for males and skips females (requires PED file with -s)

bcftools cnv [OPTIONS] FILE

Copy number variation caller, requires a VCF annotated with the Illumina’s B-allele frequency (BAF) and Log R Ratio intensity (LRR) values. The HMM considers the following copy number states: CN 2 (normal), 1 (single-copy loss), 0 (complete loss), 3 (single-copy gain).

General Options:

-c, --control-sample string

optional control sample name. If given, pairwise calling is performed and the -P option can be used

-f, --AF-file file

read allele frequencies from a tab-delimited file with the columns CHR,POS,REF,ALT,AF

-o, --output-dir path

output directory

-p, --plot-threshold float

call matplotlib to produce plots for chromosomes with quality at least float, useful for visual inspection of the calls. With -p 0, plots for all chromosomes will be generated. If not given, a matplotlib script will be created but not called.

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --query-sample string

query sample name

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

HMM Options:

-a, --aberrant float[,float]

fraction of aberrant cells in query and control. The hallmark of duplications and contaminations is the BAF value of heterozygous markers which is dependent on the fraction of aberrant cells. Sensitivity to smaller fractions of cells can be increased by setting -a to a lower value. Note however, that this comes at the cost of increased false discovery rate.

-b, --BAF-weight float

relative contribution from BAF

-d, --BAF-dev float[,float]

expected BAF deviation in query and control, i.e. the noise observed in the data.

-e, --err-prob float

uniform error probability

-l, --LRR-weight float

relative contribution from LRR. With noisy data, this option can have big effect on the number of calls produced. In truly random noise (such as in simulated data), the value should be set high (1.0), but in the presence of systematic noise when LRR are not informative, lower values result in cleaner calls (0.2).

-L, --LRR-smooth-win int

reduce LRR noise by applying moving average given this window size

-O, --optimize float

iteratively estimate the fraction of aberrant cells, down to the given fraction. Lowering this value from the default 1.0 to say, 0.3, can help discover more events but also increases noise

-P, --same-prob float

the prior probability of the query and the control sample being the same. Setting to 0 calls both independently, setting to 1 forces the same copy number state in both.

-x, --xy-prob float

the HMM probability of transition to another copy number state. Increasing this values leads to smaller and more frequent calls.

bcftools concat [OPTIONS] FILE1 FILE2 […​]

Concatenate or combine VCF/BCF files. All source files must have the same sample columns appearing in the same order. Can be used, for example, to concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel VCF into one. The input files must be sorted by chr and position. The files must be given in the correct order to produce sorted VCF on output unless the -a, --allow-overlaps option is specified. With the --naive option, the files are concatenated without being recompressed, which is very fast..

-a, --allow-overlaps

First coordinate of the next file can precede last record of the current file.

-c, --compact-PS

Do not output PS tag at each site, only at the start of a new phase set block.

-d, --rm-dups snps|indels|both|all|exact

Output duplicate records of specified type present in multiple files only once. Note that records duplicate within one file are not removed with this option, for that use bcftools norm -d instead.
In other words, the default behavior of the program is similar to unix "cat" in that when two files contain a record with the same position, that position will appear twice on output. With -d, every line that finds a matching record in another file will be printed only once.
Requires -a, --allow-overlaps.

-D, --remove-duplicates

Alias for -d exact

-f, --file-list FILE

Read file names from FILE, one file name per line.

-l, --ligate

Ligate phased VCFs by matching phase at overlapping haplotypes. Note that the option is intended for VCFs with perfect overlap, sites in overlapping regions present in one but missing in the other are dropped.

--ligate-force

Keep all sites and ligate even non-overlapping chunks and chunks with imperfect overlap

--ligate-warn

Drop sites in imperfect overlaps

--no-version

see Common Options

-n, --naive

Concatenate VCF or BCF files without recompression. This is very fast but requires that all files are of the same type (all VCF or all BCF) and have the same headers. This is because all tags and chromosome names in the BCF body rely on the order of the contig and tag definitions in the header. A header check compatibility is performed and the program throws an error if it is not safe to use the option.

--naive-force

Same as --naive, but header compatibility is not checked. Dangerous, use with caution.

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

-q, --min-PQ INT

Break phase set if phasing quality is lower than INT

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options. Requires -a, --allow-overlaps.

-R, --regions-file FILE

see Common Options. Requires -a, --allow-overlaps.

--regions-overlap 0|1|2

see Common Options

--threads INT

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

bcftools consensus [OPTIONS] FILE

Create consensus sequence by applying VCF variants to a reference fasta file. By default, the program will apply all ALT variants to the reference fasta to obtain the consensus sequence. Using the --sample (and, optionally, --haplotype) option will apply genotype (haplotype) calls from FORMAT/GT. Note that the program does not act as a primitive variant caller and ignores allelic depth information, such as INFO/AD or FORMAT/AD. For that, consider using the setGT plugin.

-a, --absent CHAR

replace positions absent from VCF with CHAR

-c, --chain FILE

write a chain file for liftover

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-f, --fasta-ref FILE

reference sequence in fasta format

-H, --haplotype N|R|A|I|LR|LA|SR|SA|NpIu

choose which allele from the FORMAT/GT field to use (the codes are case-insensitive):

N

N={1,2,3,…​}, the allele index within the genotype, regardless of phasing

R

the REF allele (in heterozygous genotypes)

A

the ALT allele (in heterozygous genotypes)

I

IUPAC code for all genotypes

LR, LA

the longer allele. If both have the same length, use the REF allele (LR), or the ALT allele (LA)

SR, SA

the shorter allele. If both have the same length, use the REF allele (SR), or the ALT allele (SA)

NpIu

N={1,2,3,…​}, the allele index within genotype for phased genotypes and IUPAC code for unphased genotypes. For example, 1pIu or 2pIu

Note that the -H, --haplotype option requires the -s, --samples option, unless exactly one sample is present in the VCF

-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-I, --iupac-codes

output variants in the form of IUPAC ambiguity codes determined from FORMAT/GT fields. By default all samples are used and can be subset with -s, --samples and -S, --samples-file. Use -s - to ignore samples and use only the REF and ALT columns. NOTE: prior to version 1.17 the IUPAC codes were determined solely from REF,ALT columns and sample genotypes were not considered.

--mark-del CHAR

instead of removing sequence, insert character CHAR for deletions

--mark-ins uc|lc|CHAR

highlight inserted sequence in uppercase (uc), lowercase (lc), or a provided character CHAR, leaving the rest of the sequence as is

--mark-snv uc|lc

highlight substitutions in uppercase (uc), lowercase (lc), or a provided character CHAR, leaving the rest of the sequence as is

-m, --mask FILE

BED file or TAB file with regions to be replaced with N (the default) or as specified by the next --mask-with option. See discussion of --regions-file in Common Options for file format details.

--mask-with CHAR|lc|uc

replace sequence from --mask with CHAR, skipping overlapping variants, or change to lowercase (lc) or uppercase (uc)

-M, --missing CHAR

instead of skipping the missing genotypes, output the character CHAR (e.g. "?")

-o, --output FILE

write output to a file

--regions-overlap 0|1|2

how to treat VCF variants overlapping the target region in the fasta file: see Common Options

-s, --samples LIST

apply variants of the listed samples. See also the option -I, --iupac-codes

-S, --samples-file FILE

apply variants of the samples listed in the file. See also the option -I, --iupac-codes

Examples:

    # Apply variants present in sample "NA001", output IUPAC codes for hets
    bcftools consensus -i -s NA001 -f in.fa in.vcf.gz > out.fa

    # Create consensus for one region. The fasta header lines are then expected
    # in the form ">chr:from-to". Ignore samples and consider only the REF and ALT columns
    samtools faidx ref.fa 8:11870-11890 | bcftools consensus -s - in.vcf.gz -o out.fa

    # For more examples see http://samtools.github.io/bcftools/howtos/consensus-sequence.html
Notes:

Masking options are applied in the following order

  1. mask regions with --mask-with character if --mask is given. All overlapping VCF variants are ignored

  2. replace sequence not mentioned in the VCF with the requested character if --absent is given

  3. finally apply --mark-del, --mark-ins, --mark-snv masks

bcftools convert [OPTIONS] FILE

VCF input options:

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file FILE

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples LIST

see Common Options

-S, --samples-file FILE

see Common Options

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

VCF output options:

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

--threads INT

see Common Options

GEN/SAMPLE conversion:

-G, --gensample2vcf prefix or gen-file,sample-file

convert IMPUTE2 output to VCF. One of the ID columns ("SNP ID" or "rsID" in https://www.cog-genomics.org/plink/2.0/formats#gen) must be of the form "CHROM:POS_REF_ALT" to detect possible strand swaps.  
When the --vcf-ids option is given, the other column (autodetected) is used to fill the ID column of the VCF.  
See also -g and --3N6 options.

-g, --gensample prefix or gen-file,sample-file

convert from VCF to gen/sample format used by IMPUTE2 and SHAPEIT. The columns of .gen file format are ID1,ID2,POS,A,B followed by three genotype probabilities P(AA), P(AB), P(BB) for each sample. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". When the --vcf-ids option is given, the second column is set to match the ID column of the VCF.  
See also -G and --3N6 options.  
The file .gen and .sample file format are:

  .gen (with --3N6 --vcf-ids)
  ---------------------------
  chr1 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1 0
  chr1 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 0 1

  .gen (with --vcf-ids)
  ---------------------------
  1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1 0
  1:111494194_C_T rsID2 111494194 C T 0 1 0 0 0 1

  .gen (the default)
  ------------------------------
  1:111485207_G_A 1:111485207_G_A 111485207 G A 0 1 0 0 1 0
  1:111494194_C_T 1:111494194_C_T 111494194 C T 0 1 0 0 0 1

  .sample
  -------
  ID_1 ID_2 missing
  0 0 0
  sample1 sample1 0
  sample2 sample2 0
--3N6

Expect/Create files in the 3*N+6 column format. This is the new .gen file format with the first column containing the chromosome name, see https://www.cog-genomics.org/plink/2.0/formats#gen

--tag STRING

tag to take values for .gen file: GT,PL,GL,GP

--sex FILE

output sex column in the sample file. The FILE format is

    MaleSample    M
    FemaleSample  F
--vcf-ids

output VCF IDs in the second column instead of CHROM:POS_REF_ALT

gVCF conversion:

--gvcf2vcf

convert gVCF to VCF, expanding REF blocks into sites. Note that the -i and -e options work differently with this switch. In this situation the filtering expressions define which sites should be expanded and which sites should be left unmodified, but all sites are printed on output. In order to drop sites, stream first through bcftools view.

-f, --fasta-ref file

reference sequence in fasta format. Must be indexed with samtools faidx

HAP/SAMPLE conversion:

--hapsample2vcf prefix or hap-file,sample-file

convert from hap/sample format to VCF. The columns of .hap file are similar to .gen file above, but there are only two haplotype columns per sample. Note that the first or the second column of the .hap file is expected to be in the form "CHR:POS_REF_ALT[_END]", with the _END being optional for defining the INFO/END tag when ALT is a symbolic allele. For example:

  .hap (with --vcf-ids)
  ---------------------
  1:111485207_G_A rsID1 111485207 G A 0 1 0 0
  1:111495231_A_<DEL>_111495784 rsID3 111495231 A <DEL> 0 0 1 0

  .hap (the default)
  ------------------
  1 1:111485207_G_A 111485207 G A 0 1 0 0
  1 1:111495231_A_<DEL>_111495784 111495231 A <DEL> 0 0 1 0
--hapsample prefix or hap-file,sample-file

convert from VCF to hap/sample format used by IMPUTE2 and SHAPEIT. The columns of .hap file begin with ID,RSID,POS,REF,ALT. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT".

--haploid2diploid

with -h option converts haploid genotypes to homozygous diploid genotypes. For example, the program will print 0 0 instead of the default 0 -. This is useful for programs which do not handle haploid genotypes correctly.

--sex FILE

output sex column in the sample file. The FILE format is

    MaleSample    M
    FemaleSample  F
--vcf-ids

the second column of the .hap file holds the VCF ids, the first column is of the form "CHR:POS_REF_ALT[_END]". Without the option, the format follows https://www.cog-genomics.org/plink/2.0/formats#haps with ids (the second column) of the form "CHR:POS_REF_ALT[_END]"

HAP/LEGEND/SAMPLE conversion:

-H, --haplegendsample2vcf prefix or hap-file,legend-file,sample-file

convert from hap/legend/sample format used by IMPUTE2 to VCF. See also -h, --hapslegendsample below.

-h, --haplegendsample prefix or hap-file,legend-file,sample-file

convert from VCF to hap/legend/sample format used by IMPUTE2 and SHAPEIT. The columns of .legend file ID,POS,REF,ALT. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". The .sample file is quite basic at the moment with columns for population, group and sex expected to be edited by the user. For example:

  .hap
  -----
  0 1 0 0 1 0
  0 1 0 0 0 1

  .legend
  -------
  id position a0 a1
  1:111485207_G_A 111485207 G A
  1:111494194_C_T 111494194 C T

  .sample
  -------
  sample population group sex
  sample1 sample1 sample1 2
  sample2 sample2 sample2 2
--haploid2diploid

with -h option converts haploid genotypes to homozygous diploid genotypes. For example, the program will print 0 0 instead of the default 0 -. This is useful for programs which do not handle haploid genotypes correctly.

--sex FILE

output sex column in the sample file. The FILE format is

    MaleSample    M
    FemaleSample  F
--vcf-ids

output VCF IDs instead of "CHROM:POS_REF_ALT". Note that this option can be used with --haplegendsample but not with --haplegendsample2vcf.

TSV conversion:

--tsv2vcf file

convert from TSV (tab-separated values) format (such as generated by 23andMe) to VCF. The input file fields can be tab- or space- delimited

-c, --columns list

comma-separated list of fields in the input file. In the current version, the fields CHROM, POS, ID, and AA or REF, ALT are expected and can appear in arbitrary order. Columns which should be ignored in the input file can be indicated by "-". The AA field lists alleles on the forward reference strand, for example "CC" or "CT" for diploid genotypes or "C" for haploid genotypes (sex chromosomes). Insertions and deletions are supported only with REF and ALT but not with AA. Missing data can be indicated with "--" or ".".

-f, --fasta-ref file

reference sequence in fasta format. Must be indexed with samtools faidx

-s, --samples LIST

list of sample names. See Common Options

-S, --samples-file FILE

file of sample names. See Common Options

Example:

# Convert 23andme results into VCF
bcftools convert -c ID,CHROM,POS,AA -s SampleName -f 23andme-ref.fa --tsv2vcf 23andme.txt -o out.vcf.gz

# Convert tab-delimited file into a sites-only VCF (no genotypes), in this example first column to be ignored
bcftools convert -c -,CHROM,POS,REF,ALT -f ref.fa --tsv2vcf calls.txt -o out.bcf

bcftools csq [OPTIONS] FILE

Haplotype aware consequence predictor which correctly handles combined variants such as MNPs split over multiple VCF records, SNPs separated by an intron (but adjacent in the spliced transcript) or nearby frame-shifting indels which in combination in fact are not frame-shifting.

The output VCF is annotated with INFO/BCSQ and FORMAT/BCSQ tag (configurable with the -c option). The latter is a bitmask of indexes to INFO/BCSQ, with interleaved haplotypes. See the usage examples below for using the %TBCSQ converter in query for extracting a more human readable form from this bitmask. The construction of the bitmask limits the number of consequences that can be referenced per sample in the FORMAT/BCSQ tags. By default this is 15, but if more are required, see the --ncsq option.

Note that the program annotates only records with a functional consequence and intergenic regions will pass through unchanged.

The program requires on input a VCF/BCF file, the reference genome in fasta format (--fasta-ref) and genomic features in the GFF3 format downloadable from the Ensembl website (--gff-annot), and outputs an annotated VCF/BCF file. Currently, only Ensembl GFF3 files are supported.

By default, the input VCF should be phased. If phase is unknown, or only partially known, the --phase option can be used to indicate how to handle unphased data. Alternatively, haplotype aware calling can be turned off with the --local-csq option.

If conflicting (overlapping) variants within one haplotype are detected, a warning will be emitted and predictions will be based on only the first variant in the analysis.

Symbolic alleles are not supported. They will remain unannotated in the output VCF and are ignored for the prediction analysis.

-c, --custom-tag STRING

use this custom tag to store consequences rather than the default BCSQ tag

-B, --trim-protein-seq INT

abbreviate protein-changing predictions to maximum of INT aminoacids. For example, instead of writing the whole modified protein sequence with potentially hundreds of aminoacids, with -B 1 only an abbreviated version such as 25E..329>25G..94 will be written.

--dump-gff FILE

dump the parsed GFF into a gzipped FILE. Intended for debugging purposes, shows how is the input GFF viewed by the program.

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-f, --fasta-ref FILE

reference sequence in fasta format (required)

--force

run even if some sanity checks fail. Currently the option enables skipping transcripts in malformatted GFFs with incorrect phase

-g, --gff-annot FILE

GFF3 annotation file (required), such as http://ftp.ensembl.org/pub/current_gff3/homo_sapiens/. The script gff2gff can help with conversion from non-standard GFF formats. An example of a minimal working GFF file:

    # The program looks for "CDS", "exon", "three_prime_UTR" and "five_prime_UTR" lines,
    # looks up their parent transcript (determined from the "Parent=transcript:" attribute),
    # the gene (determined from the transcript's "Parent=gene:" attribute), and the biotype
    # (the most interesting is "protein_coding").
    #
    # Empty and commented lines are skipped, the following GFF columns are required
    #   1.  chromosome
    #   2.  IGNORED
    #   3.  type (CDS, exon, three_prime_UTR, five_prime_UTR, gene, transcript, etc.)
    #   4.  start of the feature (1-based)
    #   5.  end of the feature (1-based)
    #   6.  IGNORED
    #   7.  strand (+ or -)
    #   8.  phase (0, 1, 2 or .)
    #   9.  semicolon-separated attributes (see below)
    #
    # Attributes required for
    #   gene lines:
    #   - ID=gene:<gene_id>
    #   - biotype=<biotype>
    #   - Name=<gene_name>      [optional]
    #
    #   transcript lines:
    #   - ID=transcript:<transcript_id>
    #   - Parent=gene:<gene_id>
    #   - biotype=<biotype>
    #
    #   other lines (CDS, exon, five_prime_UTR, three_prime_UTR):
    #   - Parent=transcript:<transcript_id>
    #
    # Supported biotypes:
    #   - see the function gff_parse_biotype() in bcftools/csq.c

    1   ignored_field  gene            21  2148  .   -   .   ID=gene:GeneId;biotype=protein_coding;Name=GeneName
    1   ignored_field  transcript      21  2148  .   -   .   ID=transcript:TranscriptId;Parent=gene:GeneId;biotype=protein_coding
    1   ignored_field  three_prime_UTR 21  2054  .   -   .   Parent=transcript:TranscriptId
    1   ignored_field  exon            21  2148  .   -   .   Parent=transcript:TranscriptId
    1   ignored_field  CDS             21  2148  .   -   1   Parent=transcript:TranscriptId
    1   ignored_field  five_prime_UTR  210 2148  .   -   .   Parent=transcript:TranscriptId
-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-l, --local-csq

switch off haplotype-aware calling, run localized predictions considering only one VCF record at a time

-n, --ncsq INT

maximum number of per-haplotype consequences to consider for each site. The INFO/BCSQ column includes all consequences, but only the first INT will be referenced by the FORMAT/BCSQ fields. The default value is 15 which corresponds to one 32-bit integer per diploid sample, after accounting for values reserved by the BCF specification. Note that increasing the value leads to increased size of the output BCF.

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type t|b|u|z|v[0-9]

see Common Options. In addition, a custom tab-delimited plain text output can be printed (t).

-p, --phase a|m|r|R|s

how to handle unphased heterozygous genotypes:

a

take GTs as is, create haplotypes regardless of phase (0/1 → 0|1)

m

merge all GTs into a single haplotype (0/1 → 1, 1/2 → 1)

r

require phased GTs, throw an error on unphased heterozygous GTs

R

create non-reference haplotypes if possible (0/1 → 1|1, 1/2 → 1|2)

s

skip unphased heterozygous GTs

-q, --quiet

suppress warning messages

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file FILE

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples LIST

samples to include or "-" to apply all variants and ignore samples

-S, --samples-file FILE

see Common Options

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

--unify-chr-names 0|1

Automatically detect and unify chromosome naming conventions in the GFF, fasta and VCF, such as "chrX" vs "X". The chromosome names in the output VCF will match that of the input VCF. The default is to attempt the automatic translation.

-v, --verbose INT

verbosity level (0-2)

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

Examples:

    # Basic usage
    bcftools csq -f hs37d5.fa -g Homo_sapiens.GRCh37.82.gff3.gz in.vcf -Ob -o out.bcf

    # Extract the translated haplotype consequences. The following TBCSQ variations
    # are recognised:
    #   %TBCSQ    .. print consequences in all haplotypes in separate columns
    #   %TBCSQ{0} .. print the first haplotype only
    #   %TBCSQ{1} .. print the second haplotype only
    #   %TBCSQ{*} .. print a list of unique consequences present in either haplotype
    bcftools query -f'[%CHROM\t%POS\t%SAMPLE\t%TBCSQ\n]' out.bcf

Examples of BCSQ annotation:

    # Two separate VCF records at positions 2:122106101 and 2:122106102
    # change the same codon. This UV-induced C>T dinucleotide mutation
    # has been annotated fully at the position 2:122106101 with
    #   - consequence type
    #   - gene name
    #   - ensembl transcript ID
    #   - coding strand (+ fwd, - rev)
    #   - amino acid position (in the coding strand orientation)
    #   - list of corresponding VCF variants
    # The annotation at the second position gives the position of the full
    # annotation
    BCSQ=missense|CLASP1|ENST00000545861|-|1174P>1174L|122106101G>A+122106102G>A
    BCSQ=@122106101

    # A frame-restoring combination of two frameshift insertions C>CG and T>TGG
    BCSQ=@46115084
    BCSQ=inframe_insertion|COPZ2|ENST00000006101|-|18AGRGP>18AQAGGP|46115072C>CG+46115084T>TGG

    # Stop gained variant
    BCSQ=stop_gained|C2orf83|ENST00000264387|-|141W>141*|228476140C>T

    # The consequence type of a variant downstream from a stop are prefixed with *
    BCSQ=*missense|PER3|ENST00000361923|+|1028M>1028T|7890117T>C

Supported consequence types

3_prime_utr
5_prime_utr
coding_sequence
feature_elongation
frameshift
inframe_altering
inframe_deletion
inframe_insertion
intergenic
intron
missense
non_coding
splice_acceptor
splice_donor
splice_region
start_lost
start_retained
stop_gained
stop_lost
stop_retained
synonymous

See also https://ensembl.org/info/genome/variation/prediction/predicted_data.html

bcftools filter [OPTIONS] FILE

Apply fixed-threshold filters.

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-g, --SnpGap INT[:'indel',mnp,bnd,other,overlap]

filter SNPs within INT base pairs of an indel or other other variant type. The following example demonstrates the logic of --SnpGap 3 applied on a deletion and an insertion:

The SNPs at positions 1 and 7 are filtered, positions 0 and 8 are not:
         0123456789
    ref  .G.GT..G..
    del  .A.G-..A..
Here the positions 1 and 6 are filtered, 0 and 7 are not:
         0123-456789
    ref  .G.G-..G..
    ins  .A.GT..A..
-G, --IndelGap INT

filter clusters of indels separated by INT or fewer base pairs allowing only one to pass. The following example demonstrates the logic of --IndelGap 2 applied on a deletion and an insertion:

The second indel is filtered:
         012345678901
    ref  .GT.GT..GT..
    del  .G-.G-..G-..
And similarly here, the second is filtered:
         01 23 456 78
    ref  .A-.A-..A-..
    ins  .AT.AT..AT..
-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

--mask [^]REGION

Soft filter regions, prepepend "^" to negate. Requires -s, --soft-filter.

-M, --mask-file [^]FILE

Soft filter regions listed in a file, "^" to negate. Requires -s, --soft-filter.

--mask-overlap 0|1|2

Same as --regions-overlap but for --mask/--mask-file. See Common Options. [1]

-m, --mode [+x]

define behaviour at sites with existing FILTER annotations. The default mode replaces existing filters of failed sites with a new FILTER string while leaving sites which pass untouched when non-empty and setting to "PASS" when the FILTER string is absent. The "+" mode appends new FILTER strings of failed sites instead of replacing them. The "x" mode resets filters of sites which pass to "PASS". Modes "+" and "x" can both be set.

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --soft-filter STRING|+

annotate FILTER column with STRING or, with +, a unique filter name generated by the program ("Filter%d"). Applies to records that do not meet filter expression.

-S, --set-GTs .|0

set genotypes of failed samples to missing value (.) or reference allele (0)

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

--threads INT

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

bcftools gtcheck [OPTIONS] [-g genotypes.vcf.gz] query.vcf.gz

Checks sample identity. The program can operate in two modes. If the -g option is given, the identity of samples from query.vcf.gz is checked against the samples in the -g file. Without the -g option, multi-sample cross-check of samples in query.vcf.gz is performed.

Note that the interpretation of the discordance score depends on the options provided (specifically -e and -u) and on the available annotations (FORMAT/PL vs FORMAT/GT). The discordance score can be interpreted as the number of mismatching genotypes only if GT-vs-GT matching is performed.

--distinctive-sites NUM[,MEM[,DIR]]

Find sites that can distinguish between at least NUM sample pairs. If the number is smaller or equal to 1, it is interpreted as the fraction of pairs. The optional MEM string sets the maximum memory used for in-memory sorting and DIR is the temporary directory for external sorting. This option requires also --pairs to be given.

--dry-run

Stop after first record to estimate required time.

-e, --exclude [qry|gt]:'EXPRESSION'

Exclude sites from query file (qry:) or genotype file (gt:) for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-E, --error-probability INT

Interpret genotypes and genotype likelihoods probabilistically. The value of INT represents genotype quality when GT tag is used (e.g. Q=30 represents one error in 1,000 genotypes and Q=40 one error in 10,000 genotypes) and is ignored when PL tag is used (in that case an arbitrary non-zero integer can be provided).  
 
If -E is set to 0, the discordance score can be interpreted as the number of mismatching genotypes, but only in the GT-vs-GT matching mode. See the -u, --use option below for additional notes and caveats.  
 
If performance is an issue, set -E 0 for faster run times but less accurate results.  
 
Note that in previous versions of bcftools (⇐1.18), this option used to be a smaller case -e. It changed to make room for the filtering option -e, --exclude to stay consistent across other commands.

-g, --genotypes FILE

VCF/BCF file with reference genotypes to compare against

-H, --homs-only

Homozygous genotypes only, useful with low coverage data (requires -g, --genotypes)

-i, --include [qry|gt]:'EXPRESSION'

Include sites from query file (qry:) or genotype file (gt:) for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

--n-matches INT

Print only top INT matches for each sample, 0 for unlimited. Use negative value to sort by HWE probability rather than the number of discordant sites. Note that average score is used to determine the top matches, not absolute values.

--no-HWE-prob

Disable calculation of HWE probability to reduce memory requirements with comparisons between very large number of sample pairs.

-o, --output FILE

Write to FILE rather than to standard output, where it is written by default.

-O, --output-type t|z

Write a plain (t) or compressed (z) text tab-delimited output.

-p, --pairs LIST

A comma-separated list of sample pairs to compare. When the -g option is given, the first sample must be from the query file, the second from the -g file, third from the query file etc (qry,gt[,qry,gt..]). Without the -g option, the pairs are created the same way but both samples are from the query file (qry,qry[,qry,qry..])

-P, --pairs-file FILE

A file with tab-delimited sample pairs to compare. The first sample in the pair must come from the query file, the second from the genotypes file when -g is given

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

Restrict to comma-separated list of regions, see Common Options

*-R, --regions-file' FILE

Restrict to regions listed in a file, see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples [qry|gt]:'LIST': List of query samples or -g samples. If neither -s nor -S are given, all possible sample pair combinations are compared

-S, --samples-file [qry|gt]:'FILE' File with the query or -g samples to compare. If neither -s nor -S are given, all possible sample pair combinations are compared

-t, --targets file

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

-u, --use TAG1[,TAG2]

specifies which tag to use in the query file (TAG1) and the -g (TAG2) file. By default, the PL tag is used in the query file and, when available, the GT tags in the -g file.  
 
Note that when the requested tag is not available, the program will attempt to use the other tag. The output includes the number of sites that were matched by the four possible modes (for example GT-vs-GT or GT-vs-PL).

Examples:

   # Check discordance of all samples from B against all samples in A
   bcftools gtcheck -g A.bcf B.bcf

   # Limit comparisons to the given list of samples
   bcftools gtcheck -s gt:a1,a2,a3 -s qry:b1,b2 -g A.bcf B.bcf

   # Compare only two pairs a1,b1 and a1,b2
   bcftools gtcheck -p a1,b1,a1,b2 -g A.bcf B.bcf

By default, prints all headers from the specified input file to standard output in VCF format. The input file may be in VCF or BCF format; if no FILE is specified, standard input will be read. With appropriate options, only some of the headers and/or additionally some of the variant records will be printed.

The bcftools head command outputs VCF headers almost exactly as they appear in the input file: it may add a ##FILTER=<ID=PASS> header if not already present, but it never adds version or command line information itself.

Options:

-h, --header INT

Display only the first INT header lines. By default, all header lines are displayed.

-n, --records INT

Also display the first INT variant records. By default, no variant records are displayed.

-s, --samples INT

Display the first INT variant records including the last #CHROM header line with samples. Running with -s 0 alone outputs the #CHROM header line only. Note that the list of samples, with each sample per line, can be obtained with bcftools query using the option -l, --list-samples.

bcftools index [OPTIONS] in.bcf|in.vcf.gz

Creates index for bgzip compressed VCF/BCF files for random access. CSI (coordinate-sorted index) is created by default. The CSI format supports indexing of chromosomes up to length 2^31. TBI (tabix index) index files, which support chromosome lengths up to 2^29, can be created by using the -t/--tbi option or using the tabix program packaged with htslib. When loading an index file, bcftools will try the CSI first and then the TBI.

Indexing options:

-c, --csi

generate CSI-format index for VCF/BCF files [default]

-f, --force

overwrite index if it already exists

-m, --min-shift INT

set minimal interval size for CSI indices to 2^INT; default: 14

-o, --output FILE

output file name. If not set, then the index will be created using the input file name plus a .csi or .tbi extension

-t, --tbi

generate TBI-format index for VCF files

--threads INT

see Common Options

Stats options:

-a, --all

Used in conjunction with -s, --stats, print per contig stats for all contigs, even those with zero records and those for which no stats are recorded in the index file (shown as .).

-n, --nrecords

print the number of records based on the CSI or TBI index files

-s, --stats

Print per contig stats based on the CSI or TBI index files. Output format is three tab-delimited columns listing the contig name, contig length (. if unknown) and number of records for the contig. Contigs with zero records are not printed by default.

bcftools isec [OPTIONS] A.vcf.gz B.vcf.gz […​]

Creates intersections, unions and complements of VCF files. Depending on the options, the program can output records from one (or more) files which have (or do not have) corresponding records with the same position in the other files.

-c, --collapse snps|indels|both|all|some|none

see Common Options

-C, --complement

output positions present only in the first file but missing in the others

-e, --exclude -|EXPRESSION

exclude sites for which EXPRESSION is true. If -e (or -i) appears only once, the same filtering expression will be applied to all input files. Otherwise, -e or -i must be given for each input file. To indicate that no filtering should be performed on a file, use "-" in place of EXPRESSION, as shown in the example below. For valid expressions see EXPRESSIONS.

-f, --apply-filters LIST

see Common Options

-i, --include EXPRESSION

include only sites for which EXPRESSION is true. See discussion of -e, --exclude above.

-f, --file-list FILE

Read file names from FILE, one file name per line.

-n, --nfiles [+-=]INT|~BITMAP

output positions present in this many (=), this many or more (+), this many or fewer (-), or the exact same (~) files

-o, --output FILE

see Common Options. When several files are being output, their names are controlled via -p instead.

-O, --output-type b|u|z|v[0-9]

see Common Options

-p, --prefix DIR

if given, subset each of the input files accordingly. See also -w.

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

-w, --write LIST

comma-separated list of input files to output given as 1-based indices. With -p and no -w, all files are written.

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and defaults to tbi for vcf.gz and csi for bcf. This is done automatically with the -p option if the output format is compressed.

Examples:

Create intersection and complements of two sets saving the output in dir/*

    bcftools isec -p dir A.vcf.gz B.vcf.gz

Filter sites in A (require INFO/MAF>=0.01) and B (require INFO/dbSNP) but not in C, and create an intersection, including only sites which appear in at least two of the files after filters have been applied

    bcftools isec -e'MAF<0.01' -i'dbSNP=1' -e- A.vcf.gz B.vcf.gz C.vcf.gz -n +2 -p dir

Extract and write records from A shared by both A and B using exact allele match

    bcftools isec -p dir -n=2 -w1 A.vcf.gz B.vcf.gz

Extract records private to A or B comparing by position only

    bcftools isec -p dir -n-1 -c all A.vcf.gz B.vcf.gz

Print a list of records which are present in A and B but not in C and D

    bcftools isec -n~1100 -c all A.vcf.gz B.vcf.gz C.vcf.gz D.vcf.gz

bcftools merge [OPTIONS] A.vcf.gz B.vcf.gz […​]

Merge multiple VCF/BCF files from non-overlapping sample sets to create one multi-sample file. For example, when merging file A.vcf.gz containing samples S1, S2 and S3 and file B.vcf.gz containing samples S3 and S4, the output file will contain five samples named S1, S2, S3, 2:S3 and S4.

Note that it is responsibility of the user to ensure that the sample names are unique across all files. If they are not, the program will exit with an error unless the option --force-samples is given. The sample names can be also given explicitly using the --print-header and --use-header options.

Note that only records from different files can be merged, never from the same file. For "vertical" merge take a look at bcftools concat or bcftools norm -m instead.

--force-no-index

synonymous to --no-index

--force-samples

if the merged files contain duplicate samples names, proceed anyway. Duplicate sample names will be resolved by prepending the index of the file as it appeared on the command line to the conflicting sample name (see 2:S3 in the above example).

--force-single

run even if only one file is given on input

--print-header

print only merged header and exit

--use-header FILE

use the VCF header in the provided text FILE

-0 --missing-to-ref

assume genotypes at missing sites are 0/0

-f, --apply-filters LIST

see Common Options

-F, --filter-logic x|+

Set the output record to PASS if any of the inputs is PASS (x), or apply all filters (+), which is the default.

-g, --gvcf -|FILE

merge gVCF blocks, INFO/END tag is expected. If the reference fasta file FILE is not given and the dash (-) is given, unknown reference bases generated at gVCF block splits will be substituted with N’s. The --gvcf option uses the following default INFO rules: -i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max and the following missing rules: -M PL:max,AD:0.

-i, --info-rules -|TAG:METHOD[,…​]

Rules for merging INFO fields (scalars or vectors) or - to disable the default rules. METHOD is one of sum, avg, min, max, join. Default is DP:sum,DP4:sum if these fields exist in the input files. Fields with no specified rule will take the value from the first input file. The merged QUAL value is currently set to the maximum. This behaviour is not user controllable at the moment.

-l, --file-list FILE

Read file names from FILE, one file name per line.

-L, --local-alleles INT

Sites with many alternate alleles can require extremely large storage space which can exceed the 2GB size limit representable by BCF. This is caused by Number=G tags (such as FORMAT/PL) which store a value for each combination of reference and alternate alleles. The -L, --local-alleles option allows replacement of such tags with a localized tag (FORMAT/LPL) which only includes a subset of alternate alleles relevant for that sample. A new FORMAT/LAA tag is added which lists 1-based indices of the alternate alleles relevant (local) for the current sample. The number INT gives the maximum number of alternate alleles that can be included in the PL tag. The default value is 0 which disables the feature and outputs values for all alternate alleles.

-m, --merge snps|indels|both|snp-ins-del|all|none|id[,*]

The option controls what types of multiallelic records can be created. If single asterisk * is appended, the unobserved allele <*> or <NON_REF> will be removed at variant sites; if two asterisks ** are appended, the unobserved allele will be removed all sites.

-m none        ..  no new multiallelics, output multiple records instead
-m snps        ..  allow multiallelic SNP records
-m indels      ..  allow multiallelic indel records
-m both        ..  both SNP and indel records can be multiallelic
-m both,*      ..  same as above but remove <*> (or <NON_REF>) from variant sites
-m both,**     ..  same as above but remove <*> (or <NON_REF>) at all sites
-m all         ..  SNP records can be merged with indel records
-m snp-ins-del ..  allow multiallelic SNVs, insertions, deletions, but don't mix them
-m id          ..  merge by ID
-M, --missing-rules -|TAG:METHOD[,…​]

Rules for merging vector tags at multiallelic sites. When input files have different alternate alleles, vector fields pertaining to unobserved alleles are set to missing (.) by default. The METHOD is one of . (the default, use missing values), NUMBER (use a constant value, e.g. 0), max (the maximum value observed for other alleles in the sample). When --gvcf option is set, the rule -M PL:max,AD:0 is implied. This can be overridden with providing -M - or -M PL:.,AD:.. Note that if the unobserved allele is explicitly present as <*> or <NON_REF>, then its corresponding value will be used regardless of -M settings.

--no-index

the option allows files to be merged without indexing them first. In order for this option to work, the user must ensure that the input files have chromosomes in the same order and consistent with the order of sequences in the VCF header.

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

--threads INT

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

bcftools mpileup [OPTIONS] -f ref.fa in.bam [in2.bam […​]]

Generate VCF or BCF containing genotype likelihoods for one or multiple alignment (BAM or CRAM) files. This is based on the original samtools mpileup command (with the -v or -g options) producing genotype likelihoods in VCF or BCF format, but not the textual pileup output. The mpileup command was transferred to bcftools in order to avoid errors resulting from use of incompatible versions of samtools and bcftools when using in the mpileup+bcftools call pipeline.

Individuals are identified from the SM tags in the @RG header lines. Multiple individuals can be pooled in one alignment file, also one individual can be separated into multiple files. If sample identifiers are absent, each input file is regarded as one sample.

Note that there are two orthogonal ways to specify locations in the input file; via -r region and -t positions. The former uses (and requires) an index to do random access while the latter streams through the file contents filtering out the specified regions, requiring no index. The two may be used in conjunction. For example a BED file containing locations of genes in chromosome 20 could be specified using -r 20 -t chr20.bed, meaning that the index is used to find chromosome 20 and then it is filtered for the regions listed in the BED file. Also note that the -r option can be much slower than -t with many regions and can require more memory when multiple regions and many alignment files are processed.

Input options

-6, --illumina1.3+

Assume the quality is in the Illumina 1.3+ encoding.

-A, --count-orphans

Include anomalous read pairs in variant calling, i.e. reads with flag PAIRED but not PROPER_PAIR set. By default such reads are discarded.

-b, --bam-list FILE

List of input alignment files, one file per line [null]

-B, --no-BAQ

Disable probabilistic realignment for the computation of base alignment quality (BAQ). BAQ is the Phred-scaled probability of a read base being misaligned. Applying this option greatly helps to reduce false SNPs caused by misalignments.

-C, --adjust-MQ INT

Coefficient for downgrading mapping quality for reads containing excessive mismatches. Mismatches are counted as a proportion of the number of aligned bases ("M", "X" or "=" CIGAR operations), along with their quality, to derive an upper-bound of the mapping quality. Original mapping qualities lower than this are left intact, while higher ones are capped at the new adjusted score.

The exact formula is complex and likely tuned to specific instruments and specific alignment tools, so this option is disabled by default (indicated as having a zero value). Variables in the formulae and their meaning are defined below.

Variable    Meaning / formula
M           The number of matching CIGAR bases (operation "M", "X" or "=").
X           The number of substitutions with quality >= 13.
SubQ        The summed quality of substitution bases included in X, capped
            at a maximum of quality 33 per mismatching base.
ClipQ       The summed quality of soft-clipped or hard-clipped bases. This
            has no minimum or maximum quality threshold per base.  For
            hard-clipped bases the per-base quality is taken as 13.

T           SubQ - 10 * log10(M^X / X!) + ClipQ/5
Cap         MAX(0, INT * sqrt((INT - T) / INT))

Some notes on the impact of this.

  • As the number of mismatches increases, the mapping quality cap reduces, eventually resulting in discarded alignments.

  • High quality mismatches reduces the cap faster than low quality mismatches.

  • The starting INT value also acts as a hard cap on mapping quality, even when zero mismatches are observed.

  • Indels have no impact on the mapping quality.

    The intent of this option is to work around aligners that compute a mapping quality using a local alignment without having any regard to the degree of clipping required or consideration of potential contamination or large scale insertions with respect to the reference. A record may align uniquely and have no close second match, but having a high number of mismatches may still imply that the reference is not the correct site.

    However we do not recommend use of this parameter unless you fully understand the impact of it and have determined that it is appropriate for your sequencing technology.

-D, --full-BAQ

Run the BAQ algorithm on all reads, not just those in problematic regions. This matches the behaviour for Bcftools 1.12 and earlier.

By default mpileup uses heuristics to decide when to apply the BAQ algorithm. Most sequences will not be BAQ adjusted, giving a CPU time closer to --no-BAQ, but it will still be applied in regions with suspected problematic alignments. This has been tested to work well on single sample data with even allele frequency, but the reliability is unknown for multi-sample calling and for low allele frequency variants so full BAQ is still recommended in those scenarios.

-d, --max-depth INT

At a position, read maximally INT reads per input file. Note that the original samtools mpileup command had a minimum value of 8000/n where n was the number of input files given to mpileup. This means that in samtools mpileup the default was highly likely to be increased and the -d parameter would have an effect only once above the cross-sample minimum of 8000. This behavior was problematic when working with a combination of single- and multi-sample bams, therefore in bcftools mpileup the user is given the full control (and responsibility), and an informative message is printed instead [250]

-E, --redo-BAQ

Recalculate BAQ on the fly, ignore existing BQ tags

-f, --fasta-ref FILE

The faidx-indexed reference file in the FASTA format. The file can be optionally compressed by bgzip. Reference is required by default unless the --no-reference option is set [null]

--no-reference

Do not require the --fasta-ref option.

-G, --read-groups FILE

list of read groups to include or exclude if prefixed with "^". One read group per line. This file can also be used to assign new sample names to read groups by giving the new sample name as a second white-space-separated field, like this: "read_group_id new_sample_name". If the read group name is not unique, also the bam file name can be included: "read_group_id file_name sample_name". If all reads from the alignment file should be treated as a single sample, the asterisk symbol can be used: "* file_name sample_name". Alignments without a read group ID can be matched with "?". NOTE: The meaning of bcftools mpileup -G is the opposite of samtools mpileup -G.

    RG_ID_1
    RG_ID_2  SAMPLE_A
    RG_ID_3  SAMPLE_A
    RG_ID_4  SAMPLE_B
    RG_ID_5  FILE_1.bam  SAMPLE_A
    RG_ID_6  FILE_2.bam  SAMPLE_A
    *        FILE_3.bam  SAMPLE_C
    ?        FILE_3.bam  SAMPLE_D
--indels-2.0

A new EXPERIMENTAL indel calling model which aims to address some known deficiencies of the current indel calling algorithm. Specifically, it uses diploid reference consensus sequence. Note that in the current version it has the potential to increase sensitivity but at the cost of decreased specificity. Only works with short-read sequencing technologies.

--indels-cns

Another EXPERIMENTAL indel calling method, predating indels-2.0 in PR form, but merged more recently. It also uses a diploid reference consensus, but with added parameters and heuristics to optimise for a variety of sequencing platforms. This is usually faster and more accurate than the default caller and --indels-2.0, but has not been tested on non-diploid samples and samples without approximately even allele frequency.

--no-indels-cns

May be used to turn off --indels-cns mode when using one of the newer profiles that has this enabled by default.

-q, -min-MQ INT

Minimum mapping quality for an alignment to be used [0]

-Q, --min-BQ INT

Minimum base quality for a base to be considered [13]

--max-BQ INT

Caps the base quality to a maximum value [60]. This can be particularly useful on technologies that produce overly optimistic high qualities, leading to too many false positives or incorrect genotype assignments.

-r, --regions CHR|CHR:POS|CHR:FROM-TO|CHR:FROM-[,…​]

Only generate mpileup output in given regions. Requires the alignment files to be indexed. If used in conjunction with -l then considers the intersection; see Common Options

-R, --regions-file FILE

As for -r, --regions, but regions read from FILE; see Common Options

--regions-overlap 0|1|2

see Common Options

--ignore-RG

Ignore RG tags. Treat all reads in one alignment file as one sample.

--ls, --skip-all-set

Skip reads with all of the FLAG bits set [null]

--ns, --skip-any-set

Skip reads with any of the FLAG bits set. This option replaces and is synonymous to the deprecated --ff, --excl-flags [UNMAP,SECONDARY,QCFAIL,DUP]

--lu, --skip-all-unset

Skip reads with all of the FLAG bits unset. This option replaces and is synonymous to the deprecated --rf, --incl-flags [null]

--nu, --skip-any-unset

Skip reads with any of the FLAG bits unset [null]

-s, --samples LIST

list of sample names. See Common Options

-S, --samples-file FILE

file of sample names to include or exclude if prefixed with "^". One sample per line. This file can also be used to rename samples by giving the new sample name as a second white-space-separated column, like this: "old_name new_name". If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\ a\ good\ sample\ name".

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

-x, --ignore-overlaps

Disable read-pair overlap detection.

--seed INT

Set the random number seed used when sub-sampling deep regions [0].

Output options

-a, --annotate LIST

Comma-separated list of FORMAT and INFO tags to output. (case-insensitive, the "FORMAT/" prefix is optional, and use "?" to list available annotations on the command line) [null]:

FORMAT/AD   .. Allelic depth (Number=R,Type=Integer)
FORMAT/ADF  .. Allelic depths on the forward strand (Number=R,Type=Integer)
FORMAT/ADR  .. Allelic depths on the reverse strand (Number=R,Type=Integer)
FORMAT/DP   .. Number of high-quality bases (Number=1,Type=Integer)
FORMAT/SP   .. Phred-scaled strand bias P-value (Number=1,Type=Integer)
FORMAT/SCR  .. Number of soft-clipped reads (Number=1,Type=Integer)

INFO/AD     .. Total allelic depth (Number=R,Type=Integer)
INFO/ADF    .. Total allelic depths on the forward strand (Number=R,Type=Integer)
INFO/ADR    .. Total allelic depths on the reverse strand (Number=R,Type=Integer)
INFO/SCR    .. Number of soft-clipped reads (Number=1,Type=Integer)

FORMAT/DV   .. Deprecated in favor of FORMAT/AD; Number of high-quality non-reference bases, (Number=1,Type=Integer)
FORMAT/DP4  .. Deprecated in favor of FORMAT/ADF and FORMAT/ADR; Number of high-quality ref-forward, ref-reverse,
               alt-forward and alt-reverse bases (Number=4,Type=Integer)
FORMAT/DPR  .. Deprecated in favor of FORMAT/AD; Number of high-quality bases for each observed allele (Number=R,Type=Integer)
INFO/DPR    .. Deprecated in favor of INFO/AD; Number of high-quality bases for each observed allele (Number=R,Type=Integer)
-g, --gvcf INT[,…​]

output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers. For example, passing 5,15 will group sites into two types of gVCF blocks, the first with minimum per-sample DP from the interval [5,15) and the latter with minimum depth 15 or more. In this example, sites with minimum per-sample depth less than 5 will be printed as separate records, outside of gVCF blocks.

--no-version

see Common Options

-o, --output FILE

Write output to FILE, rather than the default of standard output. (The same short option is used for both --open-prob and --output. If -o's argument contains any non-digit characters other than a leading + or - sign, it is interpreted as --output. Usually the filename extension will take care of this, but to write to an entirely numeric filename use -o ./123 or --output 123.)

-O, --output-type b|u|z|v[0-9]

see Common Options

--threads INT

see Common Options

-U, --mwu-u

The the previous Mann-Whitney U test score from version 1.12 and earlier. This is a probability score, but importantly it folds probabilities above or below the desired score into the same P. The new Mann-Whitney U test score is a "Z score", expressing the score as the number of standard deviations away from the mean (with zero being matching the mean). It keeps both positive and negative values. This can be important for some tests where errors are asymmetric.

This option changes the INFO field names produced back to the ones
used by the earlier Bcftools releases.  For excample BQBZ becomes
BQB.
-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

Options for SNP/INDEL genotype likelihood computation

-X, --config STR

Specify a platform specific configuration profile. Specifying the profile as "list" will list the available profile names and the parameters they change. There are profiles named after a release, which should be used if you wish to ensure forward compatibility of results. The non-versioned names (eg "illumina") will always point to the most recent set of parameters for that instrument type. The current values are:

1.12            -Q13 -h100 -m1
bgi
bgi-1.20        --indels-cns -B --indel-size 80 -F0.1 --indel-bias 0.9
                --seqq-offset 120
illumina-1.18   [ default values ]
illumina
illumina-1.20   --indels-cns --seqq-offset 125
ont             -B -Q5 --max-BQ 30 -I
ont-sup
ont-sup-1.20    --indels-cns -B -Q1 --max-BQ 35 --delta-BQ 99 -F0.2
                -o15 -e1 -h110 --del-bias 0.4 --indel-bias 0.7
                --poly-mqual --seqq-offset 130 --indel-size 80
pacbio-ccs-1.18 -D -Q5 --max-BQ 50 -F0.1 -o25 -e1 -M99999
pacbio-ccs
pacbio-ccs-1.20  --indels-cns -B -Q5 --max-BQ 50 -F0.1 -o25 -e1 -h300
                 --delta-BQ 10 --del-bias 0.4 --poly-mqual
                 --indel-bias 0.9 --seqq-offset 118 --indel-size 80
                 --score-vs-ref 0.7
ultima
ultima-1.20      --indels-cns -B -Q1 --max-BQ 30 --delta-BQ 10 -F0.15
                 -o20 -e10 -h250 --del-bias 0.3 --indel-bias 0.7
                 --poly-mqual --seqq-offset 140 --score-vs-ref 0.3
                 --indel-size 80
--ar, --ambig-reads drop|incAD|incAD0

What to do with ambiguous indel reads that do not span an entire short tandem repeat region: discard ambiguous reads from calling and do not increment high-quality AD depth counters (drop), exclude from calling but increment AD counters proportionally (incAD), exclude from calling and increment the first value of the AD counter (incAD0) [drop]

-e, --ext-prob INT

Phred-scaled gap extension sequencing error probability. Reducing INT leads to longer indels [20]

-F, --gap-frac FLOAT

Minimum fraction of gapped reads [0.002]

-h, --tandem-qual INT

Coefficient for modeling homopolymer errors. Given an l-long homopolymer run, the sequencing error of an indel of size s is modeled as INT*s/l [500] Increasing this informs the caller that indels in long homopolymers are more likely genuine and less likely to be sequencing artifacts. Hence increasing tandem-qual will have higher recall and lower precision. Bcftools 1.12 and earlier had a default of 100, which was tuned around more error prone instruments. Note changing this may have a minor impact on SNP calling too. For maximum SNP calling accuracy, it may be preferable to adjust this lower again, although this will adversely affect indels.

--indel-bias FLOAT

Skews the indel scores up or down, trading recall (low false-negative) vs precision (low false-positive) [1.0]. In Bcftools 1.12 and earlier this parameter didn’t exist, but had an implied value of 1.0. If you are planning to do heavy filtering of variants, selecting the best quality ones only (favouring precision over recall), it is advisable to set this lower (such as 0.75) while higher depth samples or where you favour recall rates over precision may work better with a higher value such as 2.0.

--del-bias FLOAT

Skews the likelihood of deletions over insertions. Defaults to an even distribution value of 1.0. Lower values imply a higher rate of false positive deletions (meaning candidate deletions are less likely to be real).

--indel-size INT

Indel window size to use when assessing the quality of candidate indels. Note that although the window size approximately corresponds to the maximum indel size considered, it is not an exact threshold [110]

--seqq-offset INT

Tunes the importance of indel sequence quality per depth. The final "seqQ" quality used is "offset - 5*MIN(depth,20)". [120]

--poly-mqual

Use the lowest quality value within a homopolymer run, instead of the quality immediately adjacent to the indel. This may be important for unclocked instruments, particularly ones with a flow chemistry where runs of bases of identical type are incorporated together.

-I, --skip-indels

Do not perform INDEL calling

-L, --max-idepth INT

Skip INDEL calling if the average per-sample depth is above INT [250]

-m, --min-ireads INT

Minimum number gapped reads for indel candidates INT [1]

-M, --max-read-len INT

The maximum read length permitted by the BAQ algorithm [500]. Variants are still called on longer reads, but they will not be passed through the BAQ method. This limit exists to prevent excessively long BAQ times and high memory usage. Note if partial BAQ is enabled with -D then raising this parameter will likely not have a significant a CPU cost.

-o, --open-prob INT

Phred-scaled gap open sequencing error probability. Reducing INT leads to more indel calls. (The same short option is used for both --open-prob and --output. When -o’s argument contains only an optional + or - sign followed by the digits 0 to 9, it is interpreted as --open-prob.) [40]

-p, --per-sample-mF

Apply -m and -F thresholds per sample to increase sensitivity of calling. By default both options are applied to reads pooled from all samples.

-P, --platforms STR

Comma-delimited list of platforms (determined by @RG-PL) from which indel candidates are obtained. It is recommended to collect indel candidates from sequencing technologies that have low indel error rate such as ILLUMINA [all]

Examples:

Call SNPs and short INDELs, then mark low quality sites and sites with the read depth exceeding a limit. (The read depth should be adjusted to about twice the average read depth as higher read depths usually indicate problematic regions which are often enriched for artefacts.) One may consider to add -C50 to mpileup if mapping quality is overestimated for reads containing excessive mismatches. Applying this option usually helps for BWA-backtrack alignments, but may not other aligners.

    bcftools mpileup -Ou -f ref.fa aln.bam | \
    bcftools call -Ou -mv | \
    bcftools filter -s LowQual -e '%QUAL<20 || DP>100' > var.flt.vcf

bcftools norm [OPTIONS] file.vcf.gz

Left-align and normalize indels, check if REF alleles match the reference, split multiallelic sites into multiple rows; recover multiallelics from multiple rows. Left-alignment and normalization will only be applied if the --fasta-ref option is supplied.

-a, --atomize

Decompose complex variants, e.g. split MNVs into consecutive SNVs. See also --atom-overlaps and --old-rec-tag.

--atom-overlaps .|*

Alleles missing because of an overlapping variant can be set either to missing (.) or to the star alele (*), as recommended by the VCF specification. IMPORTANT: Note that asterisk is expaneded by shell and must be put in quotes or escaped by a backslash:

    # Before atomization:
    100  CC  C,GG   1/2

    # After:
    #   bcftools norm -a --atom-overlaps .
    100	 C	 G      ./1
    100	 CC	 C      1/.
    101	 C	 G      ./1

    # After:
    #   bcftools norm -a --atom-overlaps '*'
    #   bcftools norm -a --atom-overlaps \*
    100	 C	 G,*    2/1
    100	 CC	 C,*    1/2
    101	 C	 G,*    2/1
-c, --check-ref e|w|x|s

what to do when incorrect or missing REF allele is encountered: exit (e), warn (w), exclude (x), or set/fix (s) bad sites. The w option can be combined with x and s. Note that s can swap alleles and will update genotypes (GT) and AC counts, but will not attempt to fix PL or other fields. Also note, and this cannot be stressed enough, that s will NOT fix strand issues in your VCF, do NOT use it for that purpose!!! (Instead see http://samtools.github.io/bcftools/howtos/plugin.af-dist.html and <http://samtools.github.io/bcftools/howtos/plugin.fixref.html>.)

-d, --rm-dup snps|indels|both|all|exact

If a record is present multiple times, output only the first instance. See also --collapse in Common Options.

-D, --remove-duplicates

If a record is present in multiple files, output only the first instance. Alias for -d none, deprecated.

-e, --exclude EXPRESSION

do not normalize input records for which EXPRESSION is true. For valid expressions see EXPRESSIONS. Note that duplicate removal ignores this option.

-f, --fasta-ref FILE

reference sequence. Supplying this option will turn on left-alignment and normalization, however, see also the --do-not-normalize option below.

--force

try to proceed with -m- even if malformed tags with incorrect number of fields are encountered, discarding such tags. (Experimental, use at your own risk.)

-g, --gff-annot FILE

when a GFF file is provided, follow HGVS 3’rule and right-align variants in transcripts on the forward strand. In case of overlapping transcripts, the default mode is to left-align the variant. For a description of the supported GFF3 file format see bcftools csq.

-i, --include EXPRESSION

normalize only input records for which EXPRESSION is true. For valid expressions see EXPRESSIONS. Note that duplicate removal ignores this option.

--keep-sum TAG[,…​]

keep vector sum constant when splitting multiallelic sites. Only AD tag is currently supported. See also https://github.com/samtools/bcftools/issues/360

-m, --multiallelics -|+[snps|indels|both|any]

split multiallelic sites into biallelic records (-) or join biallelic sites into multiallelic records (+). An optional type string can follow which controls variant types which should be split or merged together: If only SNP records should be split or merged, specify snps; if both SNPs and indels should be merged separately into two records, specify both; if SNPs and indels should be merged into a single record, specify any.  
 
Note that multiallelic sites with both SNPs and indels will be split into biallelic sites with both -m -snps and -m -indels.

--multi-overlaps 0|.

use the reference (0) or missing (.) allele for overlapping alleles after splitting multiallelic sites

--no-version

see Common Options

-N, --do-not-normalize

the -c s option can be used to fix or set the REF allele from the reference -f. The -N option will not turn on indel normalisation as the -f option normally implies

--old-rec-tag STR

Add INFO/STR annotation with the original record. The format of the annotation is CHROM|POS|REF|ALT|USED_ALT_IDX.

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --strict-filter

when merging (-m+), merged site is PASS only if all sites being merged PASS

-S, --sort pos|lex

when splitting sites or processing duplicates, sort records on output by POS only (pos, the default) or by POS and lexicographically by REF+ALT (lex)

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

--threads INT

see Common Options

-v, --verbose INT

verbosity level of GFF parsing (0-2)

-w, --site-win INT

maximum distance between two records to consider when locally sorting variants which changed position during the realignment

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

bcftools [plugin NAME|+NAME] [OPTIONS] FILE — [PLUGIN OPTIONS]

A common framework for various utilities. The plugins can be used the same way as normal commands only their name is prefixed with "+". Most plugins accept two types of parameters: general options shared by all plugins followed by a separator, and a list of plugin-specific options. There are some exceptions to this rule, some plugins do not accept the common options and implement their own parameters. Therefore please pay attention to the usage examples that each plugin comes with.

VCF input options:

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

VCF output options:

--no-version

see Common Options

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

--threads INT

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

Plugin options:

-h, --help

list plugin’s options

-l, --list-plugins

List all available plugins.

By default, appropriate system directories are searched for installed plugins. You can override this by setting the BCFTOOLS_PLUGINS environment variable to a colon-separated list of directories to search. If BCFTOOLS_PLUGINS begins with a colon, ends with a colon, or contains adjacent colons, the system directories are also searched at that position in the list of directories.

-v, --verbose

print debugging information to debug plugin failure

-V, --version

print version string and exit

List of plugins coming with the distribution:

ad-bias

find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD)

add-variantkey

add VariantKey INFO fields VKX and RSX

af-dist

collect AF deviation stats and GT probability distribution given AF and assuming HWE

allele-length

count the frequency of the length of REF, ALT and REF+ALT

check-ploidy

check if ploidy of samples is consistent for all sites

check-sparsity

print samples without genotypes in a region or chromosome

color-chrs

color shared chromosomal segments, requires trio VCF with phased GTs

contrast

runs a basic association test, per-site or in a region, and checks for novel alleles and genotypes in two groups of samples. Adds the following INFO annotations:

  • PASSOC .. Fisher’s exact test probability of genotypic association (REF vs non-REF allele)

  • FASSOC .. proportion of non-REF allele in controls and cases

  • NASSOC .. number of control-ref, control-alt, case-ref and case-alt alleles

  • NOVELAL .. lists samples with a novel allele not observed in the control group

  • NOVELGT .. lists samples with a novel genotype not observed in the control group

counts

a minimal plugin which counts number of SNPs, Indels, and total number of sites.

dosage

print genotype dosage. By default the plugin searches for PL, GL and GT, in that order.

fill-from-fasta

fill INFO or REF field based on values in a fasta file

fill-tags

set various INFO tags. The list of tags supported in this version:

  • INFO/AC Number:A Type:Integer .. Allele count in genotypes

  • INFO/AC_Hom Number:A Type:Integer .. Allele counts in homozygous genotypes

  • INFO/AC_Het Number:A Type:Integer .. Allele counts in heterozygous genotypes

  • INFO/AC_Hemi Number:A Type:Integer .. Allele counts in hemizygous genotypes

  • INFO/AF Number:A Type:Float .. Allele frequency

  • INFO/AN Number:1 Type:Integer .. Total number of alleles in called genotypes

  • INFO/ExcHet Number:A Type:Float .. Test excess heterozygosity; 1=good, 0=bad

  • INFO/END Number:1 Type:Integer .. End position of the variant

  • INFO/F_MISSING Number:1 Type:Float .. Fraction of missing genotypes

  • INFO/HWE Number:A Type:Float .. HWE test (PMID:15789306); 1=good, 0=bad

  • INFO/MAF Number:A Type:Float .. Minor Allele frequency

  • INFO/NS Number:1 Type:Integer .. Number of samples with data

  • INFO/TYPE Number:. Type:String .. The record type (REF,SNP,MNP,INDEL,etc)

  • FORMAT/VAF Number:A Type:Float .. The fraction of reads with the alternate allele, requires FORMAT/AD or ADF+ADR

  • FORMAT/VAF1 Number:1 Type:Float .. The same as FORMAT/VAF but for all alternate alleles cumulatively

  • TAG=func(TAG) Number:1 Type:Integer .. Experimental support for user-defined expressions such as "DP=sum(DP)"

fixploidy

sets correct ploidy

fixref

determine and fix strand orientation

frameshifts

annotate frameshift indels

GTisec

count genotype intersections across all possible sample subsets in a vcf file

GTsubset

output only sites where the requested samples all exclusively share a genotype

guess-ploidy

determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT) in the non-PAR region of chrX.

gvcfz

compress gVCF file by resizing non-variant blocks according to specified criteria

impute-info

add imputation information metrics to the INFO field based on selected FORMAT tags

indel-stats

calculates per-sample or de novo indels stats. The usage and format is similar to smpl-stats and trio-stats

isecGT

compare two files and set non-identical genotypes to missing

mendelian

count Mendelian consistent / inconsistent genotypes (deprecated, use +mendelian2 instead)

mendelian2

count Mendelian consistent / inconsistent genotypes.

missing2ref

sets missing genotypes ("./.") to ref allele ("0/0" or "0|0")

parental-origin

determine parental origin of a CNV region

prune

prune sites by missingness, allele frequency or linkage disequilibrium. Alternatively, annotate sites with r2, Lewontin’s D' (PMID:19433632), Ragsdale’s D (PMID:31697386).

remove-overlaps

remove overlapping variants and duplicate sites

scatter

intended as an inverse to bcftools concat, scatter VCF by chunks or regions, creating multiple VCFs.

setGT

general tool to set genotypes according to rules requested by the user

smpl-stats

calculates basic per-sample stats. The usage and format is similar to indel-stats and trio-stats.

split

split VCF by sample, creating single- or multi-sample VCFs

split-vep

extract fields from structured annotations such as INFO/CSQ created by VEP or INFO/BCSQ created by bcftools/csq. These can be added as a new INFO field to the VCF or in a custom text format. See http://samtools.github.io/bcftools/howtos/plugin.split-vep.html for more.

tag2tag

Convert between similar tags, such as GL,PL,GP or QR,QA,QS or tags with localized alleles e.g. LPL,LAD. See http://samtools.github.io/bcftools/howtos/plugin.tag2tag.html for more.

trio-dnm2

screen variants for possible de-novo mutations in trios

trio-stats

calculate transmission rate in trio children. The usage and format is similar to indel-stats and smpl-stats.

trio-switch-rate

calculate phase switch rate in trio samples, children samples must have phased GTs

variant-distance

annotate sites with the distance to the nearest variant

variantkey-hex

generate unsorted VariantKey-RSid index files in hexadecimal format

Examples:

# List options common to all plugins
bcftools plugin

# List available plugins
bcftools plugin -l

# Run a plugin
bcftools plugin counts in.vcf

# Run a plugin using the abbreviated "+" notation
bcftools +counts in.vcf

# Run a plugin from an explicit location
bcftools +/path/to/counts.so in.vcf

# The input VCF can be streamed just like in other commands
cat in.vcf | bcftools +counts

# Print usage information of plugin "dosage"
bcftools +dosage -h

# Replace missing genotypes with 0/0
bcftools +missing2ref in.vcf

# Replace missing genotypes with 0|0
bcftools +missing2ref in.vcf -- -p

Plugins troubleshooting:

Things to check if your plugin does not show up in the bcftools plugin -l output:

  • Run with the -v option for verbose output: bcftools plugin -lv

  • Does the environment variable BCFTOOLS_PLUGINS include the correct path?

Plugins API:

// Short description used by 'bcftools plugin -l'
const char *about(void);

// Longer description used by 'bcftools +name -h'
const char *usage(void);

// Called once at startup, allows initialization of local variables.
// Return 1 to suppress normal VCF/BCF header output, -1 on critical
// errors, 0 otherwise.
int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr);

// Called for each VCF record, return NULL to suppress the output
bcf1_t *process(bcf1_t *rec);

// Called after all lines have been processed to clean up
void destroy(void);

bcftools polysomy [OPTIONS] file.vcf.gz

Detect number of chromosomal copies in VCFs annotates with the Illumina’s B-allele frequency (BAF) values. Note that this command is not compiled in by default, see the section Optional Compilation with GSL in the INSTALL file for help.

General options:

-o, --output-dir path

output directory

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --sample string

sample name

-t, --targets LIST

see Common Options

-T, --targets-file FILE

see Common Options

--targets-overlap 0|1|2

see Common Options

-v, --verbose

verbose debugging output which gives hints about the thresholds and decisions made by the program. Note that the exact output can change between versions.

Algorithm options:

-b, --peak-size float

the minimum peak size considered as a good match can be from the interval [0,1] where larger is stricter

-c, --cn-penalty float

a penalty for increasing copy number state. How this works: multiple peaks are always a better fit than a single peak, therefore the program prefers a single peak (normal copy number) unless the absolute deviation of the multiple peaks fit is significantly smaller. Here the meaning of "significant" is given by the float from the interval [0,1] where larger is stricter.

-f, --fit-th float

threshold for goodness of fit (normalized absolute deviation), smaller is stricter

-i, --include-aa

include also the AA peak in CN2 and CN3 evaluation. This usually requires increasing -f.

-m, --min-fraction float

minimum distinguishable fraction of aberrant cells. The experience shows that trustworthy are estimates of 20% and more.

-p, --peak-symmetry float

a heuristics to filter failed fits where the expected peak symmetry is violated. The float is from the interval [0,1] and larger is stricter

bcftools query [OPTIONS] file.vcf.gz [file.vcf.gz […​]]

Extracts fields from VCF or BCF files and outputs them in user-defined format.

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

--force-samples

continue even when some samples requested via -s/-S do not exist

-f, --format FORMAT

learn by example, see below

-F, --print-filtered STR

by default, samples failing -i/-e filtering expressions are suppressed from output when FORMAT fields are queried (for example %CHROM %POS [ %GT]). With -F, such fields will be still printed but instead of their actual value, STR will be used.

-H, --print-header

print header. By default, the header is printed with column indices, e.g. "#[1]CHROM". These can be suppressed by giving the option twice, "-HH".

-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-l, --list-samples

list sample names and exit

-N, --disable-automatic-newline

disable automatic addition of a missing newline character at the end of the formatting expression. By default, the program checks if the expression contains a newline and appends it if not, to prevent formatting the entire output into a single line by mistake. Note that versions prior to 1.18 had no automatic check and newline had to be included explicitly.

-o, --output FILE

see Common Options

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples LIST

see Common Options

-S, --samples-file FILE

see Common Options

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

-u, --allow-undef-tags

do not throw an error if there are undefined tags in the format string, print "." instead

-v, --vcf-list FILE

process multiple VCFs listed in the file

Format:

%CHROM          The CHROM column (similarly also other columns: POS, ID, REF, ALT, QUAL, FILTER)
%END            End position of the REF allele
%END0           End position of the REF allele in 0-based coordinates
%FIRST_ALT      Alias for %ALT{0}
%FORMAT         Prints all FORMAT fields or a subset of samples with -s or -S
%GT             Genotype (e.g. 0/1)
%INFO           Prints the whole INFO column
%INFO/TAG       Any tag in the INFO column
%IUPACGT        Genotype translated to IUPAC ambiguity codes (e.g. M instead of C/A)
%LINE           Prints the whole line
%MASK           Indicates presence of the site in other files (with multiple files)
%N_PASS(expr)   Number of samples that pass the filtering expression (see *<<expressions,EXPRESSIONS>>*)
%POS0           POS in 0-based coordinates
%PBINOM(TAG)    Calculate phred-scaled binomial probability, the allele index is determined from GT
%SAMPLE         Sample name
%TAG{INT}       Curly brackets to print a subfield (e.g. INFO/TAG{1}, the indexes are 0-based)
%TBCSQ          Translated FORMAT/BCSQ. See the csq command above for explanation and examples.
%TGT            Translated genotype (e.g. C/A)
%TYPE           Variant type (REF, SNP, MNP, INDEL, BND, OTHER)
%VKX            VariantKey, biallelic hexadecimal encoding of CHROM,POS,REF,ALT (https://github.com/tecnickcom/variantkey)
[]              Format fields must be enclosed in brackets to loop over all samples
\n              new line
\t              tab character
Everything else is printed verbatim.

Examples:

# Print chromosome, position, ref allele and the first alternate allele
bcftools query -f '%CHROM  %POS  %REF  %ALT{0}\n' file.vcf.gz
# Similar to above, but use tabs instead of spaces, add sample name and genotype
bcftools query -f '%CHROM\t%POS\t%REF\t%ALT[\t%SAMPLE=%GT]\n' file.vcf.gz
# Print FORMAT/GT fields followed by FORMAT/GT fields
bcftools query -f 'GQ:[ %GQ] \t GT:[ %GT]\n' file.vcf
# Make a BED file: chr, pos (0-based), end pos (1-based), id
bcftools query -f'%CHROM\t%POS0\t%END\t%ID\n' file.bcf
# Print only samples with alternate (non-reference) genotypes
bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' -i'GT="alt"' file.bcf
# Print all samples at sites with at least one alternate genotype
bcftools view -i'GT="alt"' file.bcf -Ou | bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]'
# Print phred-scaled binomial probability from FORMAT/AD tag for all heterozygous genotypes
bcftools query -i'GT="het"' -f'[%CHROM:%POS %SAMPLE %GT %PBINOM(AD)\n]' file.vcf
# Print the second value of AC field if bigger than 10. Note the (unfortunate) difference in
# index subscript notation: formatting expressions (-f) uses "{}" while filtering expressions
# (-i) use "[]". This is for historic reasons and backward-compatibility.
bcftools query -f '%AC{1}\n' -i 'AC[1]>10' file.vcf.gz
# Print all samples at sites where at least one sample has DP=1 or DP=2. In the second case
# print only samples with DP=1 or DP=2, the difference is in the logical operator used, || vs |.
bcftools query -f '[%SAMPLE %GT %DP\n]' -i 'FMT/DP=1 || FMT/DP=2' file.vcf
bcftools query -f '[%SAMPLE %GT %DP\n]' -i 'FMT/DP=1 |  FMT/DP=2' file.vcf

bcftools reheader [OPTIONS] file.vcf.gz

Modify header of VCF/BCF files, change sample names.

-f, --fai FILE

add to the header contig names and their lengths from the provided fasta index file (.fai). Lengths of existing contig lines will be updated and contig lines not present in the fai file will be removed

-h, --header FILE

new VCF header

-o, --output FILE

see Common Options

-s, --samples FILE

new sample names, one name per line, in the same order as they appear in the VCF file. Alternatively, only samples which need to be renamed can be listed as "old_name new_name\n" pairs separated by whitespaces, each on a separate line. If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\ a\ good\ sample\ name".

-T, --temp-prefix PATH

this option is ignored, but left for compatibility with earlier versions of bcftools.

--threads INT

see Common Options

bcftools roh [OPTIONS] file.vcf.gz

A program for detecting runs of homo/autozygosity. Only bi-allelic sites are considered.

The HMM model:

Notation:
  D  = Data, AZ = autozygosity, HW = Hardy-Weinberg (non-autozygosity),
  f  = non-ref allele frequency

Emission probabilities:
  oAZ = P_i(D|AZ) = (1-f)*P(D|RR) + f*P(D|AA)
  oHW = P_i(D|HW) = (1-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1-f)*P(D|RA)

Transition probabilities:
  tAZ = P(AZ|HW)  .. from HW to AZ, the -a parameter
  tHW = P(HW|AZ)  .. from AZ to HW, the -H parameter

  ci  = P_i(C)  .. probability of cross-over at site i, from genetic map
  AZi = P_i(AZ) .. probability of site i being AZ/non-AZ, scaled so that AZi+HWi = 1
  HWi = P_i(HW)

  P_{i+1}(AZ) = oAZ * max[(1 - tAZ * ci) * AZ{i-1} , tAZ * ci * (1-AZ{i-1})]
  P_{i+1}(HW) = oHW * max[(1 - tHW * ci) * (1-AZ{i-1}) , tHW * ci * AZ{i-1}]

General Options:

--AF-dflt FLOAT

in case allele frequency is not known, use the FLOAT. By default, sites where allele frequency cannot be determined, or is 0, are skipped.

--AF-tag TAG

use the specified INFO tag TAG as an allele frequency estimate instead of the default AC and AN tags. Sites which do not have TAG will be skipped.

--AF-file FILE

Read allele frequencies from a tab-delimited file containing the columns: CHROM\tPOS\tREF,ALT\tAF. The file can be compressed with bgzip and indexed with tabix -s1 -b2 -e2. Sites which are not present in the FILE or have different reference or alternate allele will be skipped. Note that such a file can be easily created from a VCF using:

    bcftools query -f'%CHROM\t%POS\t%REF,%ALT\t%INFO/TAG\n' file.vcf | bgzip -c > freqs.tab.gz
-b, --buffer-size INT[,INT]

when the entire many-sample file cannot fit into memory, a sliding buffer approach can be used. The first value is the number of sites to keep in memory. If negative, it is interpreted as the maximum memory to use, in MB. The second, optional, value sets the number of overlapping sites. The default overlap is set to roughly 1% of the buffer size.

-e, --estimate-AF FILE

estimate the allele frequency by recalculating INFO/AC and INFO/AN on the fly, using the specified TAG which can be either FORMAT/GT ("GT") or FORMAT/PL ("PL"). If TAG is not given, "GT" is assumed. Either all samples ("-") or samples listed in FILE will be included. For example, use "PL,-" to estimate AF from FORMAT/PL of all samples. If neither -e nor the other --AF-…​ options are given, the allele frequency is estimated from AC and AN counts which are already present in the INFO field.

--exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-G, --GTs-only FLOAT

use genotypes (FORMAT/GT fields) ignoring genotype likelihoods (FORMAT/PL), setting PL of unseen genotypes to FLOAT. Safe value to use is 30 to account for GT errors.

--include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-I, --skip-indels

skip indels as their genotypes are usually enriched for errors

-m, --genetic-map FILE

genetic map in the format required also by IMPUTE2. Only the first and third column are used (position and Genetic_Map(cM)). The FILE can be a single file or a file mask, where string "{CHROM}" is replaced with chromosome name.

-M, --rec-rate FLOAT

constant recombination rate per bp. In combination with --genetic-map, the --rec-rate parameter is interpreted differently, as FLOAT-fold increase of transition probabilities, which allows the model to become more sensitive yet still account for recombination hotspots. Note that also the range of the values is therefore different in both cases: normally the parameter will be in the range (1e-3,1e-9) but with --genetic-map it will be in the range (10,1000).

-o, --output FILE

Write output to the FILE, by default the output is printed on stdout

-O, --output-type s|r[z]

Generate per-site output (s) or per-region output (r). By default both types are printed and the output is uncompressed. Add z for a compressed output.

    # Output fields:
    RG = predicted homo/autozygous regions
        - Sample
        - Chromosome
        - Start
        - End
        - Length (bp)
        - Number of markers
        - Quality .. average phred score in the region from the forward-backward algorithm

    ST = per-site output showing:
        - Sample
        - Chromosome
        - Position
        - State .. predicted state from the Viterbi algorithm, 0 for normal (HW, Hardy-Weinberg) or 1 for autozygous (AZ)
        - Quality .. quality score from the forward-backward algorithm
-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples LIST

see Common Options

-S, --samples-file FILE

see Common Options

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

HMM Options:

-a, --hw-to-az FLOAT

P(AZ|HW) transition probability from AZ (autozygous) to HW (Hardy-Weinberg) state

-H, --az-to-hw FLOAT

P(HW|AZ) transition probability from HW to AZ state

-V, --viterbi-training FLOAT

estimate HMM parameters using Baum-Welch algorithm, using the convergence threshold FLOAT, e.g. 1e-10 (experimental)

bcftools sort [OPTIONS] file.bcf

-m, --max-mem FLOAT[kMG]

Maximum memory to use. Approximate, affects the number of temporary files written to the disk. Note that if the command fails at this step because of too many open files, your system limit on the number of open files ("ulimit") may need to be increased.

-o, --output FILE

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

-T, --temp-dir DIR

Use this directory to store temporary files. If the last six characters of the string DIR are XXXXXX, then these are replaced with a string that makes the directory name unique.

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

bcftools stats [OPTIONS] A.vcf.gz [B.vcf.gz]

Parses VCF or BCF and produces text file stats which is suitable for machine processing and can be plotted using plot-vcfstats. When two files are given, the program generates separate stats for intersection and the complements. By default only sites are compared, -s/-S must given to include also sample columns. When one VCF file is specified on the command line, then stats by non-reference allele frequency, depth distribution, stats by quality and per-sample counts, singleton stats, etc. are printed. When two VCF files are given, then stats such as concordance (Genotype concordance by non-reference allele frequency, Genotype concordance by sample, Non-Reference Discordance) and correlation are also printed. Per-site discordance (PSD) is also printed in --verbose mode.

--af-bins LIST|FILE

comma separated list of allele frequency bins (e.g. 0.1,0.5,1) or a file listing the allele frequency bins one per line (e.g. 0.1\n0.5\n1)

--af-tag TAG

allele frequency INFO tag to use for binning. By default the allele frequency is estimated from AC/AN, if available, or directly from the genotypes (GT) if not.

-1, --1st-allele-only

consider only the 1st alternate allele at multiallelic sites

-c, --collapse snps|indels|both|all|some|none

see Common Options

-d, --depth INT,INT,INT

ranges of depth distribution: min, max, and size of the bin

--debug

produce verbose per-site and per-sample output

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-E, --exons file.gz

tab-delimited file with exons for indel frameshifts statistics. The columns of the file are CHR, FROM, TO, with 1-based, inclusive, positions. The file is BGZF-compressed and indexed with tabix

    tabix -s1 -b2 -e3 file.gz
-f, --apply-filters LIST

see Common Options

-F, --fasta-ref ref.fa

faidx indexed reference sequence file to determine INDEL context

-i, --include EXPRESSION

include only sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-I, --split-by-ID

collect stats separately for sites which have the ID column set ("known sites") or which do not have the ID column set ("novel sites").

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-s, --samples LIST

see Common Options

-S, --samples-file FILE

see Common Options

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

-u, --user-tstv <TAG[:min:max:n]>

collect Ts/Tv stats for any tag using the given binning [0:1:100]

-v, --verbose

produce verbose per-site and per-sample output

bcftools view [OPTIONS] file.vcf.gz [REGION […​]]

View, subset and filter VCF or BCF files by position and filtering expression. Convert between VCF and BCF. Former bcftools subset.

Output options

-G, --drop-genotypes

drop individual genotype information (after subsetting if -s option is set)

-h, --header-only

output the VCF header only (see also bcftools head)

-H, --no-header

suppress the header in VCF output

--with-header

output both VCF header and records (this is the default, but the option is useful for explicitness or to reset the effects of -h or -H)

-l, --compression-level [0-9]

compression level. 0 stands for uncompressed, 1 for best speed and 9 for best compression.

--no-version

see Common Options

-O, --output-type b|u|z|v[0-9]

see Common Options

-o, --output FILE: output file name. If not present, the default is to print to standard output (stdout).

-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-R, --regions-file file

see Common Options

--regions-overlap 0|1|2

see Common Options

-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…​]

see Common Options

-T, --targets-file file

see Common Options

--targets-overlap 0|1|2

see Common Options

--threads INT

see Common Options

-W[FMT], -W[=FMT], --write-index[=FMT]

Automatically index the output file. FMT is optional and can be one of "tbi" or "csi" depending on output file format.

Subset options:

-A, --trim-unseen-alleles

remove the unseen allele <*> or <NON_REF> at variant sites when the option is given once (-A) or at all sites when the options is given twice (-AA).

-a, --trim-alt-alleles

remove alleles not seen in the genotype fields from the ALT column. Note that if no alternate allele remains after trimming, the record itself is not removed but ALT is set to ".". If the option -s or -S is given, removes alleles not seen in the subset. INFO and FORMAT tags declared as Type=A, G or R will be trimmed as well.

--force-samples

only warn about unknown subset samples

-I, --no-update

do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN)

-s, --samples LIST

see Common Options. Note that it is possible to create multiple subsets simultaneously using the split plugin.

-S, --samples-file FILE

see Common Options. Note that it is possible to create multiple subsets simultaneously using the split plugin.

Filter options:

Note that filter options below dealing with counting the number of alleles will, for speed, first check for the values of AC and AN in the INFO column to avoid parsing all the genotype (FORMAT/GT) fields in the VCF. This means that filters like --uncalled, --exclude-uncalled', or --min-af 0.1 will be calculated from INFO/AC and INFO/AN when available or FORMAT/GT otherwise. However, it will not attempt to use any other existing field, like INFO/AF for example. For that, use --exclude AF<0.1 instead.

Also note that one must be careful when sample subsetting and filtering is performed in a single command because the order of internal operations can influence the result. For example, the -i/-e filtering is performed before sample removal, but the -P filtering is performed after, and some are inherently ambiguous, for example allele counts can be taken from the INFO column when present but calculated on the fly when absent. Therefore it is strongly recommended to spell out the required order explicitly by separating such commands into two steps. (Make sure to use the -O u option when piping!)

-c, --min-ac INT[:nref|:alt1|:minor|:major|:'nonmajor']

minimum allele count (INFO/AC) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference (nref, the default), 1st alternate (alt1), the least frequent (minor), the most frequent (major) or sum of all but the most frequent (nonmajor) alleles.

-C, --max-ac INT[:nref|:alt1|:minor|:'major'|:'nonmajor']

maximum allele count (INFO/AC) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference (nref, the default), 1st alternate (alt1), the least frequent (minor), the most frequent (major) or sum of all but the most frequent (nonmajor) alleles.

-e, --exclude EXPRESSION

exclude sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-f, --apply-filters LIST

see Common Options

-g, --genotype [^][hom|het|miss]

include only sites with one or more homozygous (hom), heterozygous (het) or missing (miss) genotypes. When prefixed with ^, the logic is reversed; thus ^het excludes sites with heterozygous genotypes.

-i, --include EXPRESSION

include sites for which EXPRESSION is true. For valid expressions see EXPRESSIONS.

-k, --known

print known sites only (ID column is not ".")

-m, --min-alleles INT

print sites with at least INT alleles listed in REF and ALT columns

-M, --max-alleles INT

print sites with at most INT alleles listed in REF and ALT columns. Use -m2 -M2 -v snps to only view biallelic SNPs.

-n, --novel

print novel sites only (ID column is ".")

-p, --phased

print sites where all samples are phased. Haploid genotypes are considered phased. Missing genotypes considered unphased unless the phased bit is set.

-P, --exclude-phased

exclude sites where all samples are phased

-q, --min-af FLOAT[:nref|:alt1|:minor|:major|:nonmajor]

minimum allele frequency (INFO/AC / INFO/AN) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference (nref, the default), 1st alternate (alt1), the least frequent (minor), the most frequent (major) or sum of all but the most frequent (nonmajor) alleles.

-Q, --max-af FLOAT[:nref|:alt1|:minor|:major|:nonmajor]

maximum allele frequency (INFO/AC / INFO/AN) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference (nref, the default), 1st alternate (alt1), the least frequent (minor), the most frequent (major) or sum of all but the most frequent (nonmajor) alleles.

-u, --uncalled

print sites without a called genotype, i.e. print sites with all genotypes missing. Note that the missingness is determined from INFO/AN and AC tags when available to avoid parsing sample fields.

-U, --exclude-uncalled

exclude sites without a called genotype, i.e. print sites with at least one non-missing genotype. Note that the missingness is determined from INFO/AN and AC tags when available to avoid parsing sample fields.

-v, --types snps|indels|mnps|other

comma-separated list of variant types to select. Site is selected if any of the ALT alleles is of the type requested. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT. Use --include to select based on INFO tags.

-V, --exclude-types snps|indels|mnps|ref|bnd|other

comma-separated list of variant types to exclude. Site is excluded if any of the ALT alleles is of the type requested. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT. Use --exclude to exclude based on INFO tags.

-x, --private

print sites where only the subset samples carry an non-reference allele. Requires --samples or --samples-file.

-X, --exclude-private

exclude sites where only the subset samples carry an non-reference allele

bcftools help [COMMAND] | bcftools --help [COMMAND]

Display a brief usage message listing the bcftools commands available. If the name of a command is also given, e.g., bcftools help view, the detailed usage message for that particular command is displayed.

bcftools [--version|-v]

Display the version numbers and copyright information for bcftools and the important libraries used by bcftools.

bcftools [--version-only]

Display the full bcftools version number in a machine-readable format.

SCRIPTS

gff2gff

Attempts to fix a GFF file to be correctly parsed by csq.

zcat in.gff.gz | gff2gff | gzip -c > out.gff.gz

plot-vcfstats [OPTIONS] file.vchk […​]

Script for processing output of bcftools stats. It can merge results from multiple outputs (useful when running the stats for each chromosome separately), plots graphs and creates a PDF presentation.

-m, --merge

Merge vcfstats files to STDOUT, skip plotting.

-p, --prefix DIR

The output directory. This directory will be created if it does not exist.

-P, --no-PDF

Skip the PDF creation step.

-r, --rasterize

Rasterize PDF images for faster rendering. This is the default and the opposite of -v, --vectors.

-s, --sample-names

Use sample names for xticks rather than numeric IDs.

-t, --title STRING

Identify files by these titles in plots. The option can be given multiple times, for each ID in the bcftools stats output. If not present, the script will use abbreviated source file names for the titles.

-v, --vectors

Generate vector graphics for PDF images, the opposite of -r, --rasterize.

-T, --main-title STRING

Main title for the PDF.

Example:

# Generate the stats
bcftools stats -s - > file.vchk
# Plot the stats
plot-vcfstats -p outdir file.vchk
# The final looks can be customized by editing the generated
# 'outdir/plot.py' script and re-running manually
cd outdir && python plot.py && pdflatex summary.tex

FILTERING EXPRESSIONS

These filtering expressions are accepted by most of the commands.

Valid expressions may contain:

  • numerical constants, string constants, file names (indicated by the prefix @)

    1, 1.0, 1e-4
"String"
@file_name

  • arithmetic operators (addition, multiplication, subtraction, division, modulo)

    +, *, -, /, %

  • comparison operators

    == (same as =), >, >=, <=, <, !=

  • regex operators "\~" and its negation "!~". The expressions are case sensitive unless "/i" is added.

    INFO/HAYSTACK ~ "needle"
INFO/HAYSTACK ~ "NEEDless/i"

  • parentheses

    (, )

  • logical operators. See also the examples below and the filtering tutorial about the distinction between "&&" vs "&" and "||" vs "|".

    &&,  &, ||,  |

  • INFO tags, FORMAT tags, column names

    INFO/DP or DP
FORMAT/DV, FMT/DV, or DV
FILTER, QUAL, ID, CHROM, POS, REF, ALT[0]

  • the FILTER column can be queried as follows:

    FILTER="PASS"
FILTER="."
FILTER="A"          .. exact match, for example "A;B" does not pass
FILTER="A;B"        .. exact match, "A;B" and "B;A" pass, everything else fails
FILTER!="A"         .. exact match, for example "A;B" does pass
FILTER~"A"          .. subset match, for example both "A" and "A;B" pass
FILTER~"A;B"        .. subset match, pass only if both "A" and "B" are present
FILTER!~"A"         .. complement match, for example both "A" and "A;B" fail
FILTER!~"A;B"       .. complement match, fail if both "A" and "B" are present

  • 1 (or 0) to test the presence (or absence) of a flag

    FlagA=1 && FlagB=0

  • "." to test missing values

    DP=".", DP!=".", ALT="."

  • missing genotypes can be matched regardless of phase and ploidy (".|.", "./.", ".", "0|.") using these expressions

    GT="mis", GT~"\.", GT!~"\."

  • missing genotypes can be matched including the phase and ploidy (".|.", "./.", ".") using these expressions

    GT=".|.", GT="./.", GT="."

  • sample genotype: reference (haploid or diploid), alternate (hom or het, haploid or diploid), missing genotype, homozygous, heterozygous, haploid, ref-ref hom, alt-alt hom, ref-alt het, alt-alt het, haploid ref, haploid alt (case-insensitive)

    GT="ref"
GT="alt"
GT="mis"
GT="hom"
GT="het"
GT="hap"
GT="RR"
GT="AA"
GT="RA" or GT="AR"
GT="Aa" or GT="aA"
GT="R"
GT="A"

  • TYPE for variant type in REF,ALT columns (indel,snp,mnp,ref,bnd,other,overlap, see TERMINOLOGY). Use the regex operator "\~" to require at least one allele of the given type or the equal sign "=" to require that all alleles are of the given type. Compare

    TYPE="snp"
TYPE~"snp"
TYPE!="snp"
TYPE!~"snp"

  • array subscripts (0-based), "*" for any element, "-" to indicate a range. Note that for querying FORMAT vectors, the colon ":" can be used to select a sample and an element of the vector, as shown in the examples below.

    INFO/AF[0] > 0.3             .. first AF value bigger than 0.3
FORMAT/AD[0:0] > 30          .. first AD value of the first sample bigger than 30
FORMAT/AD[0:1]               .. first sample, second AD value
FORMAT/AD[1:0]               .. second sample, first AD value
DP4[*] == 0                  .. any DP4 value
FORMAT/DP[0]   > 30          .. DP of the first sample bigger than 30
FORMAT/DP[1-3] > 10          .. samples 2-4
FORMAT/DP[1-]  < 7           .. all samples but the first
FORMAT/DP[0,2-4] > 20        .. samples 1, 3-5
FORMAT/AD[0:1]               .. first sample, second AD field
FORMAT/AD[0:*], AD[0:] or AD[0] .. first sample, any AD field
FORMAT/AD[*:1] or AD[:1]        .. any sample, second AD field
(DP4[0]+DP4[1])/(DP4[2]+DP4[3]) > 0.3
CSQ[*] ~ "missense_variant.*deleterious"

  • in addition to array subscripts shown above, it is possible to subscript arrays of Number=R tags by alleles found in FORMAT/GT (starting with version 1.17). For example

    FORMAT/AD[GT] > 10        .. require support of more than 10 reads for each allele
FORMAT/AD[0:GT] > 10      .. same as above, but in the first sample
sSUM(FORMAT/AD[GT]) > 20  .. require total sample depth bigger than 20

  • with many samples it can be more practical to provide a file with sample names, one sample name per line

    GT[@samples.txt]="het" & binom(AD)<0.01

  • function on FORMAT tags (over samples) and INFO tags (over vector fields): maximum; minimum; arithmetic mean (AVG is synonymous with MEAN); median; standard deviation from mean; sum; string length; absolute value; number of elements:

    MAX, MIN, AVG, MEAN, MEDIAN, STDEV, SUM, STRLEN, ABS, COUNT

    Note that functions above evaluate to a single value across all samples and are intended to select sites, not samples, even when applied on FORMAT tags. However, when prefixed with SMPL_ (or "s" for brevity, e.g. SMPL_MAX or sMAX), they will evaluate to a vector of per-sample values when applied on FORMAT tags:

    SMPL_MAX, SMPL_MIN, SMPL_AVG, SMPL_MEAN, SMPL_MEDIAN, SMPL_STDEV, SMPL_SUM,
sMAX, sMIN, sAVG, sMEAN, sMEDIAN, sSTDEV, sSUM

  • two-tailed binomial test. Note that for N=0 the test evaluates to a missing value and when FORMAT/GT is used to determine the vector indices, it evaluates to 1 for homozygous genotypes.

    binom(FMT/AD)                .. GT can be used to determine the correct index
binom(AD[0],AD[1])           .. or the fields can be given explicitly
phred(binom())               .. the same as binom but phred-scaled

  • variables calculated on the fly if not present: number of alternate alleles; number of samples; count of alternate alleles; minor allele count (similar to AC but is always smaller than 0.5); frequency of alternate alleles (AF=AC/AN); frequency of minor alleles (MAF=MAC/AN); number of alleles in called genotypes; number of samples with missing genotype; fraction of samples with missing genotype; indel length (deletions negative, insertions positive, balanced substitutions zero)

    N_ALT, N_SAMPLES, AC, MAC, AF, MAF, AN, N_MISSING, F_MISSING, ILEN

  • the number (N_PASS) or fraction (F_PASS) of samples which pass the expression

    N_PASS(GQ>90 & GT!="mis") > 90
F_PASS(GQ>90 & GT!="mis") > 0.9

  • custom perl filtering. Note that this command is not compiled in by default, see the section Optional Compilation with Perl in the INSTALL file for help and misc/demo-flt.pl for a working example. The demo defined the perl subroutine "severity" which can be invoked from the command line as follows:

    perl:path/to/script.pl; perl.severity(INFO/CSQ) > 3
Notes:

  • String comparisons and regular expressions are case-insensitive

  • Comma in strings is interpreted as a separator and when multiple values are compared, the OR logic is used. Consequently, the following two expressions are equivalent but not the third:

    -i 'TAG="hello,world"'
-i 'TAG="hello" || TAG="world"'
-i 'TAG="hello" && TAG="world"'

  • Variables and function names are case-insensitive, but not tag names. For example, "qual" can be used instead of "QUAL", "strlen()" instead of "STRLEN()" , but not "dp" instead of "DP".

  • When querying multiple values, all elements are tested and the OR logic is used on the result. For example, when querying "TAG=1,2,3,4", it will be evaluated as follows:

    -i 'TAG[*]=1'   .. true, the record will be printed
-i 'TAG[*]!=1'  .. true
-e 'TAG[*]=1'   .. false, the record will be discarded
-e 'TAG[*]!=1'  .. false
-i 'TAG[0]=1'   .. true
-i 'TAG[0]!=1'  .. false
-e 'TAG[0]=1'   .. false
-e 'TAG[0]!=1'  .. true

  • When arithmetic operators are used on vectors A and B, the following logic is used to compute the resulting vector C:

    • C_i = A_i + B_i when length(A)==B(A) and sets length©=length(A)

    • C_i = A_i + B_0 when length(B)=1 and sets length©=length(A)

    • C_i = A_0 + B_i when length(A)=1 and sets length©=length(B)

    • throw an error when length(A)!=length(B) AND length(A)!=1 AND length(B)!=1

Examples:

MIN(DV)>5       .. selects the whole site, evaluates min across all values and samples
SMPL_MIN(DV)>5  .. selects matching samples, evaluates within samples
MIN(DV/DP)>0.3
MIN(DP)>10 & MIN(DV)>3
FMT/DP>10  & FMT/GQ>10 .. both conditions must be satisfied within one sample
FMT/DP>10 && FMT/GQ>10 .. the conditions can be satisfied in different samples
QUAL>10 |  FMT/GQ>10   .. true for sites with QUAL>10 or a sample with GQ>10, but selects only samples with GQ>10
QUAL>10 || FMT/GQ>10   .. true for sites with QUAL>10 or a sample with GQ>10, plus selects all samples at such sites
TYPE="snp" && QUAL>=10 && (DP4[2]+DP4[3] > 2)
COUNT(GT="hom")=0      .. no homozygous genotypes at the site
AVG(GQ)>50             .. average (arithmetic mean) of genotype qualities bigger than 50
ID=@file               .. selects lines with ID present in the file
ID!=@~/file            .. skip lines with ID present in the ~/file
INFO/TAG=@file         .. selects lines with INFO/TAG value present in the file
MAF[0]<0.05    .. select rare variants at 5% cutoff
POS>=100   .. restrict your range query, e.g. 20:100-200 to strictly sites with POS in that range.

Shell expansion:

Note that expressions must often be quoted because some characters have special meaning in the shell. An example of expression enclosed in single quotes which cause that the whole expression is passed to the program as intended:

bcftools view -i '%ID!="." & MAF[0]<0.01'

Please refer to the documentation of your shell for details.

TERMINOLOGY

The program and the documentation uses the following terminology, multiple terms can be used interchangeably for the same VCF record type

REF   ALT
---------
C     .         .. reference allele / non-variant site / ref-only site
C     T         .. SNP or SNV (single-nucleotide polymorphism or variant), used interchangeably
CC    TT        .. MNP (multi-nucleotide polymorphism)
CAAA  C         .. indel, deletion (regardless of length)
C     CAAA      .. indel, insertion (regardless of length)
C     <*>       .. gVCF block, the allele <*> is a placeholder for alternate allele possibly missed because of low coverage
C     <NON_REF> .. synonymous to <*>
C     *         .. overlapping deletion
C     <INS>     .. symbolic allele, known also as 'other [than above]'

PERFORMANCE

HTSlib was designed with BCF format in mind. When parsing VCF files, all records are internally converted into BCF representation. Simple operations, like removing a single column from a VCF file, can be therefore done much faster with standard UNIX commands, such as awk or cut. Therefore it is recommended to use BCF as input/output format whenever possible to avoid large overhead of the VCF → BCF → VCF conversion.

BUGS

Please report any bugs you encounter on the github website: http://github.com/samtools/bcftools

AUTHORS

Heng Li from the Sanger Institute wrote the original C version of htslib, samtools and bcftools. Bob Handsaker from the Broad Institute implemented the BGZF library. Petr Danecek is maintaining and further developing bcftools, together with the rest of the samtools team. Many other people contributed to the program and to the file format specifications, both directly and indirectly by providing patches, testing and reporting bugs. We thank them all.

RESOURCES

BCFtools GitHub website: http://github.com/samtools/bcftools

Samtools GitHub website: http://github.com/samtools/samtools

HTSlib GitHub website: http://github.com/samtools/htslib

File format specifications: http://samtools.github.io/hts-specs

BCFtools documentation: http://samtools.github.io/bcftools

BCFtools wiki page: https://github.com/samtools/bcftools/wiki

COPYING

The MIT/Expat License or GPL License, see the LICENSE document for details. Copyright (c) Genome Research Ltd.

bcftools-1.21/doc/bcftools.txt000066400000000000000000005077341467060157400164230ustar00rootroot00000000000000// bcftools.txt -- asciidoc template for the bcftools man page and html. // // Please do not modify bcftools.1 or bcftools.html directly, // edit this file and convert using the following commands: // // make docs // // or // // a2x --doctype manpage --format manpage bcftools.txt // a2x --doctype manpage --format xhtml bcftools.txt // // Contributions are welcome, simply edit this file and send // a pull request or email the modified file directly. // bcftools(1) =========== :doctype: manpage NAME ---- bcftools - utilities for variant calling and manipulating VCFs and BCFs. SYNOPSIS -------- *bcftools* [--version|--version-only] [--help] ['COMMAND'] ['OPTIONS'] DESCRIPTION ----------- BCFtools is a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed. Most commands accept VCF, bgzipped VCF and BCF with filetype detected automatically even when streaming from a pipe. Indexed VCF and BCF will work in all situations. Un-indexed VCF and BCF and streams will work in most, but not all situations. In general, whenever multiple VCFs are read simultaneously, they must be indexed and therefore also compressed. (Note that files with non-standard index names can be accessed as e.g. "`bcftools view -r X:2928329 file.vcf.gz##idx##non-standard-index-name`".) BCFtools is designed to work on a stream. It regards an input file "-" as the standard input (stdin) and outputs to the standard output (stdout). Several commands can thus be combined with Unix pipes. === VERSION This manual page was last updated *{date}* and refers to bcftools git version *{version}*. === BCF1 The obsolete BCF1 format output by versions of samtools \<= 0.1.19 is *not* compatible with this version of bcftools. To read BCF1 files one can use the view command from old versions of bcftools packaged with samtools versions \<= 0.1.19 to convert to VCF, which can then be read by this version of bcftools. ---- samtools-0.1.19/bcftools/bcftools view file.bcf1 | bcftools view ---- === VARIANT CALLING See 'bcftools call' for variant calling from the output of the 'samtools mpileup' command. In versions of samtools \<= 0.1.19 calling was done with 'bcftools view'. Users are now required to choose between the old samtools calling model ('-c/--consensus-caller') and the new multiallelic calling model ('-m/--multiallelic-caller'). The multiallelic calling model is recommended for most tasks. === FILTERING EXPRESSIONS See *<>* LIST OF COMMANDS ---------------- For a full list of available commands, run *bcftools* without arguments. For a full list of available options, run *bcftools* 'COMMAND' without arguments. - *<>* .. edit VCF files, add or remove annotations - *<>* .. SNP/indel calling (former "view") - *<>* .. Copy Number Variation caller - *<>* .. concatenate VCF/BCF files from the same set of samples - *<>* .. create consensus sequence by applying VCF variants - *<>* .. convert VCF/BCF to other formats and back - *<>* .. haplotype aware consequence caller - *<>* .. filter VCF/BCF files using fixed thresholds - *<>* .. check sample concordance, detect sample swaps and contamination - *<>* .. view VCF/BCF file headers - *<>* .. index VCF/BCF - *<>* .. intersections of VCF/BCF files - *<>* .. merge VCF/BCF files files from non-overlapping sample sets - *<>* .. multi-way pileup producing genotype likelihoods - *<>* .. normalize indels - *<>* .. run user-defined plugin - *<>* .. detect contaminations and whole-chromosome aberrations - *<>* .. transform VCF/BCF into user-defined formats - *<>* .. modify VCF/BCF header, change sample names - *<>* .. identify runs of homo/auto-zygosity - *<>* .. sort VCF/BCF files - *<>* .. produce VCF/BCF stats (former vcfcheck) - *<>* .. subset, filter and convert VCF and BCF files LIST OF SCRIPTS --------------- Some helper scripts are bundled with the bcftools code. - *<>* .. converts a GFF file to the format required by *<>* - *<>* .. plots the output of *<>* COMMANDS AND OPTIONS -------------------- [[common_options]] === Common Options The following options are common to many bcftools commands. See usage for specific commands to see if they apply. 'FILE':: Files can be both VCF or BCF, uncompressed or BGZF-compressed. The file "-" is interpreted as standard input. Some tools may require tabix- or CSI-indexed files. *-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none'|'id':: Controls how to treat records with duplicate positions and defines compatible records across multiple input files. Here by "compatible" we mean records which should be considered as identical by the tools. For example, when performing line intersections, the desire may be to consider as identical all sites with matching positions (*bcftools isec -c* 'all'), or only sites with matching variant type (*bcftools isec -c* 'snps'{nbsp} *-c* 'indels'), or only sites with all alleles identical (*bcftools isec -c* 'none'). 'none';; only records with identical REF and ALT alleles are compatible 'some';; only records where some subset of ALT alleles match are compatible 'all';; all records are compatible, regardless of whether the ALT alleles match or not. In the case of records with the same position, only the first will be considered and appear on output. 'snps';; any SNP records are compatible, regardless of whether the ALT alleles match or not. For duplicate positions, only the first SNP record will be considered and appear on output. 'indels';; all indel records are compatible, regardless of whether the REF and ALT alleles match or not. For duplicate positions, only the first indel record will be considered and appear on output. 'both';; abbreviation of "*-c* 'indels'{nbsp} *-c* 'snps'" 'id';; only records with identical ID column are compatible. Supported by *<>* only. *-f, --apply-filters* 'LIST':: Skip sites where FILTER column does not contain any of the strings listed in 'LIST'. For example, to include only sites which have no filters set, use *-f* '.,PASS'. *--no-version*:: Do not append version and command line information to the output VCF header. *-o, --output* 'FILE':: When output consists of a single stream, write it to 'FILE' rather than to standard output, where it is written by default. The file type is determined automatically from the file name suffix and in case a conflicting *-O* option is given, the file name suffix takes precedence. *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: Output compressed BCF ('b'), uncompressed BCF ('u'), compressed VCF ('z'), uncompressed VCF ('v'). Use the -Ou option when piping between bcftools subcommands to speed up performance by removing unnecessary compression/decompression and VCF<-->BCF conversion. {nbsp} The compression level of the compressed formats ('b' and 'z') can be set by by appending a number between 0-9. *-r, --regions* 'chr'|'chr:pos'|'chr:beg-end'|'chr:beg-'[,...]:: Comma-separated list of regions, see also *-R, --regions-file*. Overlapping records are matched even when the starting coordinate is outside of the region, unlike the *-t/-T* options where only the POS coordinate is checked. Note that *-r* cannot be used in combination with *-R*. *-R, --regions-file* 'FILE':: Regions can be specified either on command line or in a VCF, BED, or tab-delimited file (the default). The columns of the tab-delimited file can contain either positions (two-column format: CHROM, POS) or intervals (three-column format: CHROM, BEG, END), but not both. Positions are 1-based and inclusive. The columns of the tab-delimited BED file are also CHROM, POS and END (trailing columns are ignored), but coordinates are 0-based, half-open. To indicate that a file be treated as BED rather than the 1-based tab-delimited file, the file must have the ".bed" or ".bed.gz" suffix (case-insensitive). Uncompressed files are stored in memory, while bgzip-compressed and tabix-indexed region files are streamed. Note that sequence names must match exactly, "chr20" is not the same as "20". Also note that chromosome ordering in 'FILE' will be respected, the VCF will be processed in the order in which chromosomes first appear in 'FILE'. However, within chromosomes, the VCF will always be processed in ascending genomic coordinate order no matter what order they appear in 'FILE'. Note that overlapping regions in 'FILE' can result in duplicated out of order positions in the output. This option requires indexed VCF/BCF files. Note that *-R* cannot be used in combination with *-r*. *--regions-overlap* 'pos'|'record'|'variant'|'0'|'1'|'2':: This option controls how overlapping records are determined: set to *pos* or *0* if the VCF record has to have POS inside a region (this corresponds to the default behavior of *-t/-T*); set to *record* or *1* if also overlapping records with POS outside a region should be included (this is the default behavior of *-r/-R*, and includes indels with POS at the end of a region, which are technically outside the region); or set to *variant* or *2* to include only true overlapping variation (compare the full VCF representation "`TA>T-`" vs the true sequence variation "`A>-`"). *-s, --samples* \[^]'LIST':: Comma-separated list of samples to include or exclude if prefixed with "^." (Note that when multiple samples are to be excluded, the "^" prefix is still present only once, e.g. "^SAMPLE1,SAMPLE2".) The sample order is updated to reflect that given on the command line. Note that in general tags such as INFO/AC, INFO/AN, etc are not updated to correspond to the subset samples. *<>* is the exception where some tags will be updated (unless the *-I, --no-update* option is used; see *<>* documentation). To use updated tags for the subset in another command one can pipe from *view* into that command. For example: ---- bcftools view -Ou -s sample1,sample2 file.vcf | bcftools query -f %INFO/AC\t%INFO/AN\n ---- *-S, --samples-file* \[^]'FILE'[[samples_file]]:: File of sample names to include or exclude if prefixed with "^". One sample per line. See also the note above for the *-s, --samples* option. The sample order is updated to reflect that given in the input file. The command *<>* accepts an optional second column indicating ploidy (0, 1 or 2) or sex (as defined by *<>*, for example "F" or "M"), for example: ---- sample1 1 sample2 2 sample3 2 ---- or ---- sample1 M sample2 F sample3 F ---- If the second column is not present, the sex "F" is assumed. With *<> -C* 'trio', PED file is expected. The program ignores the first column and the last indicates sex (1=male, 2=female), for example: ---- ignored_column daughterA fatherA motherA 2 ignored_column sonB fatherB motherB 1 ---- *-t, --targets* \[^]'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: Similar as *-r, --regions*, but the next position is accessed by streaming the whole VCF/BCF rather than using the tbi/csi index. Both *-r* and *-t* options can be applied simultaneously: *-r* uses the index to jump to a region and *-t* discards positions which are not in the targets. Unlike *-r*, targets can be prefixed with "^" to request logical complement. For example, "^X,Y,MT" indicates that sequences X, Y and MT should be skipped. Yet another difference between the *-t/-T* and *-r/-R* is that *-r/-R* checks for proper overlaps and considers both POS and the end position of an indel, while *-t/-T* considers the POS coordinate only (by default; see also *--regions-overlap* and *--targets-overlap*). Note that *-t* cannot be used in combination with *-T*. *-T, --targets-file* \[^]'FILE':: Same *-t, --targets*, but reads regions from a file. Note that *-T* cannot be used in combination with *-t*. + With the *call -C* 'alleles' command, third column of the targets file must be comma-separated list of alleles, starting with the reference allele. Note that the file must be compressed and indexed. Such a file can be easily created from a VCF using: ---- bcftools query -f'%CHROM\t%POS\t%REF,%ALT\n' file.vcf | bgzip -c > als.tsv.gz && tabix -s1 -b2 -e2 als.tsv.gz ---- *--targets-overlap* 'pos'|'record'|'variant'|'0'|'1'|'2':: Same as *--regions-overlap* but for *-t/-T*. *--threads* 'INT':: Use multithreading with 'INT' worker threads. The option is currently used only for the compression of the output stream, only when '--output-type' is 'b' or 'z'. Default: 0. *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output files. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. Defaults to CSI unless specified otherwise. Can be used only for compressed BCF and VCF output. [[annotate]] === bcftools annotate '[OPTIONS]' 'FILE' Add or remove annotations. *-a, --annotations* 'file':: Bgzip-compressed and tabix-indexed file with annotations. The file can be VCF, BED, or a tab-delimited file with mandatory columns CHROM, POS (or, alternatively, FROM and TO), optional columns REF and ALT, and arbitrary number of annotation columns. BED files are expected to have the ".bed" or ".bed.gz" suffix (case-insensitive), otherwise a tab-delimited file is assumed. Note that in case of tab-delimited file, the coordinates POS, FROM and TO are one-based and inclusive. When REF and ALT are present, only matching VCF records will be annotated. If the END coordinate is present in the annotation file and given on command line as "`-c ~INFO/END`", then VCF records will be matched also by the INFO/END coordinate. If ID is present in the annotation file and given as "`-c ~ID`", then VCF records will be matched also by the ID column. {nbsp} + {nbsp} + When multiple ALT alleles are present in the annotation file (given as comma-separated list of alleles), at least one must match one of the alleles in the corresponding VCF record. Similarly, at least one alternate allele from a multi-allelic VCF record must be present in the annotation file. {nbsp} + {nbsp} + Missing values can be added by providing "." in place of actual value and using the missing value modifier with *-c*, such as ".TAG". {nbsp} + {nbsp} + Note that flag types, such as "INFO/FLAG", can be annotated by including a field with the value "1" to set the flag, "0" to remove it, or "." to keep existing flags. See also *-c, --columns* and *-h, --header-lines*. ---- # Sample annotation file with columns CHROM, POS, STRING_TAG, NUMERIC_TAG 1 752566 SomeString 5 1 798959 SomeOtherString 6 ---- *-c, --columns* 'list':: Comma-separated list of columns or tags to carry over from the annotation file (see also *-a, --annotations*). If the annotation file is not a VCF/BCF, 'list' describes the columns of the annotation file and must include CHROM, POS (or, alternatively, FROM,TO or BEG,END), and optionally REF and ALT. Unused columns which should be ignored can be indicated by "-". {nbsp} + {nbsp} + If the annotation file is a VCF/BCF, only the edited columns/tags must be present and their order does not matter. The columns ID, QUAL, FILTER, INFO and FORMAT can be edited, where INFO tags can be written both as "INFO/TAG" or simply "TAG", and FORMAT tags can be written as "FORMAT/TAG" or "FMT/TAG". The imported VCF annotations can be renamed as "DST_TAG:=SRC_TAG" or "FMT/DST_TAG:=FMT/SRC_TAG". {nbsp} + {nbsp} + To carry over all INFO annotations, use "INFO". To add all INFO annotations except "TAG", use "^INFO/TAG". By default, existing values are replaced. {nbsp} + {nbsp} + By default, existing tags are overwritten unless the source value is a missing value (i.e. "."). If also missing values should be carried over (and overwrite existing tags), use ".TAG" instead of "TAG". To add annotations without overwriting existing values (that is, to add tags that are absent or to add values to existing tags with missing values), use "+TAG" instead of "TAG". These can be combined, for example ".+TAG" can be used to add TAG even if the source value is missing but only if TAG does not exist in the target file; existing tags will not be overwritten. To append to existing values (rather than replacing or leaving untouched), use "=TAG" (instead of "TAG" or "+TAG"). To replace only existing values without modifying missing annotations, use "-TAG". As a special case of this, if position needs to be replaced, mark the column with the new coordinate as "-POS". (Note that in previous releases this used to be "~POS", now deprecated.) {nbsp} + {nbsp} + To match the record also by ID or INFO/END, in addition to REF and ALT, use "~ID" or "~INFO/END". Note that this works only for ID and POS, for other fields see the description of *-i* below. {nbsp} + {nbsp} + If the annotation file is not a VCF/BCF, all new annotations must be defined via *-h, --header-lines*. {nbsp} + {nbsp} + See also the *-l, --merge-logic* option. {nbsp} + {nbsp} + *Summary of `-c, --columns`:* ---- CHROM,POS,TAG .. match by chromosome and position, transfer annotation from TAG CHROM,POS,-,TAG .. same as above, but ignore the third column of the annotation file CHROM,BEG,END,TAG .. match by region (BEG,END are synonymous to FROM,TO) CHROM,POS,REF,ALT .. match by CHROM, POS, REF and ALT DST_TAG:=SRC_TAG .. transfer the SRC_TAG using the new name DST_TAG INFO .. transfer all INFO annotations ^INFO/TAG .. transfer all INFO annotations except "TAG" TAG .. add or overwrite existing target value if source is not "." and skip otherwise +TAG .. add or overwrite existing target value only it is "." .TAG .. add or overwrite existing target value even if source is "." .+TAG .. add new but never overwrite existing tag, regardless of its value; can transfer "." if target does not exist -TAG .. overwrite existing value, never add new if target does not exist =TAG .. do not overwrite but append value to existing tags ~FIELD .. use this column to match lines with -i/-e expression (see the description of -i below) ~ID .. in addition to CHROM,POS,REF,ALT match by also ID ~INFO/END .. in addition to CHROM,POS,REF,ALT match by also INFO/END ---- *-C, --columns-file* 'file':: Read the list of columns from a file (normally given via the *-c, --columns* option). "-" to skip a column of the annotation file. One column name per row, an additional space- or tab-separated field can be present to indicate the merge logic (normally given via the *-l, --merge-logic* option). This is useful when many annotations are added at once. *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>* and the extension described in *-i, --include* below. *--force*:: continue even when parsing errors, such as undefined tags, are encountered. Note this can be an unsafe operation and can result in corrupted BCF files. If this option is used, make sure to sanity check the result thoroughly. *-h, --header-lines* 'file':: Lines to append to the VCF header, see also *-c, --columns* and *-a, --annotations*. For example: ---- ##INFO= ##INFO= ---- *-I, --set-id* \[+]'FORMAT':: assign ID on the fly. The format is the same as in the *<>* command (see below). By default all existing IDs are replaced. If the format string is preceded by "+", only missing IDs will be set. For example, one can use ---- bcftools annotate --set-id +'%CHROM\_%POS\_%REF\_%FIRST_ALT' file.vcf ---- *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. {nbsp} + {nbsp} + Additionally, the command *bcftools annotate* supports expressions updated from the annotation file dynamically for each record: ---- # The field 'STR' from the -a file is required to match INFO/TAG in VCF. In the first example # the alleles REF,ALT must match, in the second example they are ignored. The option -k is required # to output also records that are not annotated. The third example shows the same concept with # a numerical expression. bcftools annotate -a annots.tsv.gz -c CHROM,POS,REF,ALT,SCORE,~STR -i'TAG={STR}' -k input.vcf bcftools annotate -a annots.tsv.gz -c CHROM,POS,-,-,SCORE,~STR -i'TAG={STR}' -k input.vcf bcftools annotate -a annots.tsv.gz -c CHROM,POS,-,-,SCORE,~INT -i'TAG>{INT}' -k input.vcf ---- *-k, --keep-sites*:: keep sites which do not pass *-i* and *-e* expressions instead of discarding them *-l, --merge-logic* 'tag:first'|'append'|'append-missing'|'unique'|'sum'|'avg'|'min'|'max'[,...]:: When multiple regions overlap a single record, this option defines how to treat multiple annotation values when setting 'tag' in the destination file: use the first encountered value ignoring the rest ('first'); append allowing duplicates ('append'); append even if the appended value is missing, i.e. is a dot ('append-missing'); append discarding duplicate values ('unique'); sum the values ('sum', numeric fields only); average the values ('avg'); use the minimum value ('min') or the maximum ('max'). + Note that this option is intended for use with BED or TAB-delimited annotation files only. Moreover, it is effective only when either 'REF' and 'ALT' or 'BEG' and 'END' *--columns* are present . + Multiple rules can be given either as a comma-separated list or giving the option multiple times. This is an experimental feature. *-m, --mark-sites* [+-]'TAG':: annotate sites which are present ("+") or absent ("-") in the *-a* file with a new INFO/TAG flag *--min-overlap* 'ANN':'VCF':: minimum overlap required as a fraction of the variant in the annotation *-a* file ('ANN'), in the target VCF file (':VCF'), or both for reciprocal overlap ('ANN:VCF'). By default overlaps of arbitrary length are sufficient. The option can be used only with the tab-delimited annotation *-a* file and with 'BEG' and 'END' columns present. *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *--pair-logic* 'snps'|'indels'|'both'|'all'|'some'|'exact':: Controls how to match records from the annotation file to the target VCF. Effective only when *-a* is a VCF or BCF. The option replaces the former uninuitive *--collapse*. See *<>* for more. *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *--rename-annots* 'file':: rename annotations according to the map in 'file', with "old_name new_name\n" pairs separated by whitespaces, each on a separate line. The old name must be prefixed with the annotation type: INFO, FORMAT, or FILTER. *--rename-chrs* 'file':: rename chromosomes according to the map in 'file', with "old_name new_name\n" pairs separated by whitespaces, each on a separate line. *-s, --samples* \[^]'LIST':: subset of samples to annotate, see also *<>* *-S, --samples-file* 'FILE':: subset of samples to annotate. If the samples are named differently in the target VCF and the *-a, --annotations* VCF, the name mapping can be given as "src_name dst_name\n", separated by whitespaces, each pair on a separate line. *--single-overlaps*:: use this option to keep memory requirements low with very large annotation files. Note, however, that this comes at a cost, only single overlapping intervals are considered in this mode. This was the default mode until the commit af6f0c9 (Feb 24 2019). *--threads* 'INT':: see *<>* *-x, --remove* 'list':: List of annotations to remove. Use "FILTER" to remove all filters or "FILTER/SomeFilter" to remove a specific filter. Similarly, "INFO" can be used to remove all INFO tags and "FORMAT" to remove all FORMAT tags except GT. To remove all INFO tags except "FOO" and "BAR", use "^INFO/FOO,INFO/BAR" (and similarly for FORMAT and FILTER). "INFO" can be abbreviated to "INF" and "FORMAT" to "FMT". *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. *Examples:* ---- # Remove three fields bcftools annotate -x ID,INFO/DP,FORMAT/DP file.vcf.gz # Remove all INFO fields and all FORMAT fields except for GT and PL bcftools annotate -x INFO,^FORMAT/GT,FORMAT/PL file.vcf # Add ID, QUAL and INFO/TAG, not replacing TAG if already present bcftools annotate -a src.bcf -c ID,QUAL,+TAG dst.bcf # Carry over all INFO and FORMAT annotations except FORMAT/GT bcftools annotate -a src.bcf -c INFO,^FORMAT/GT dst.bcf # Annotate from a tab-delimited file with six columns (the fifth is ignored), # first indexing with tabix. The coordinates are 1-based. tabix -s1 -b2 -e2 annots.tab.gz bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,POS,REF,ALT,-,TAG file.vcf # Annotate from a tab-delimited file with regions (1-based coordinates, inclusive) tabix -s1 -b2 -e3 annots.tab.gz bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,FROM,TO,TAG input.vcf # Annotate from a bed file (0-based coordinates, half-closed, half-open intervals) bcftools annotate -a annots.bed.gz -h annots.hdr -c CHROM,FROM,TO,TAG input.vcf # Transfer the INFO/END tag, matching by POS,REF,ALT and ID. This example assumes # that INFO/END is already present in the VCF header. bcftools annotate -a annots.tab.gz -c CHROM,POS,~ID,REF,ALT,INFO/END input.vcf # For (many) more examples see http://samtools.github.io/bcftools/howtos/annotate.html ---- [[call]] === bcftools call '[OPTIONS]' 'FILE' This command replaces the former *bcftools view* caller. Some of the original functionality has been temporarily lost in the process of transition under http://github.com/samtools/htslib[htslib], but will be added back on popular demand. The original calling model can be invoked with the *-c* option. ==== File format options: *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *--ploidy* 'ASSEMBLY'['?'][[ploidy]]:: predefined ploidy, use 'list' (or any other unused word) to print a list of all predefined assemblies. Append a question mark to print the actual definition. See also *--ploidy-file*. *--ploidy-file* 'FILE':: ploidy definition given as a space/tab-delimited list of CHROM, FROM, TO, SEX, PLOIDY. The SEX codes are arbitrary and correspond to the ones used by *<>*. The default ploidy can be given using the starred records (see below), unlisted regions have ploidy 2. The default ploidy definition is ---- X 1 60000 M 1 X 2699521 154931043 M 1 Y 1 59373566 M 1 Y 1 59373566 F 0 MT 1 16569 M 1 MT 1 16569 F 1 * * * M 2 * * * F 2 ---- *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* 'LIST':: see *<>* *-S, --samples-file* 'FILE':: see *<>* *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *--threads* 'INT':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. ==== Input/output options: *-A, --keep-alts*:: output all alternate alleles present in the alignments even if they do not appear in any of the genotypes *-***, --keep-unseen-allele*:: keep the unobserved allele <*> or , useful mainly for gVCF output *-f, --format-fields* 'list':: comma-separated list of FORMAT fields to output for each sample. Currently GQ and GP fields are supported. For convenience, the fields can be given as lower case letters. Prefixed with "^" indicates a request for tag removal of auxiliary tags useful only for calling. *-F, --prior-freqs* 'AN','AC':: take advantage of prior knowledge of population allele frequencies. The workflow looks like this: ---- # Extract AN,AC values from an existing VCF, such 1000Genomes bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' 1000Genomes.bcf | bgzip -c > AFs.tab.gz # If the tags AN,AC are not already present, use the +fill-tags plugin bcftools +fill-tags 1000Genomes.bcf | bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' | bgzip -c > AFs.tab.gz tabix -s1 -b2 -e2 AFs.tab.gz # Create a VCF header description, here we name the tags REF_AN,REF_AC cat AFs.hdr ##INFO= ##INFO= # Now before calling, stream the raw mpileup output through `bcftools annotate` to add the frequencies bcftools mpileup [...] -Ou | bcftools annotate -a AFs.tab.gz -h AFs.hdr -c CHROM,POS,REF,ALT,REF_AN,REF_AC -Ou | bcftools call -mv -F REF_AN,REF_AC [...] ---- *-G, --group-samples* [TAG:]'FILE'|'-':: by default, all samples are assumed to come from a single population. This option groups samples into populations and apply the HWE assumption within but not across the populations. 'FILE' is a tab-delimited text file with sample names in the first column and group names in the second column. If '-' is given instead, no HWE assumption is made at all and single-sample calling is performed. (Note that in low coverage data this inflates the rate of false positives.) The *-G* option requires the presence of per-sample FORMAT/QS or FORMAT/AD tag generated with *bcftools mpileup -a QS* (or *-a AD*). *-g, --gvcf* 'INT'[,...]:: output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers. For example, passing '5,15' will group sites into two types of gVCF blocks, the first with minimum per-sample DP from the interval [5,15) and the latter with minimum depth 15 or more. In this example, sites with minimum per-sample depth less than 5 will be printed as separate records, outside of gVCF blocks. *-i, --insert-missed* 'INT':: output also sites missed by mpileup but present in *-T, --targets-file*. *-M, --keep-masked-ref*:: output sites where REF allele is N *-V, --skip-variants* 'snps'|'indels':: skip indel/SNP sites *-v, --variants-only*:: output variant sites only ==== Consensus/variant calling options: *-c, --consensus-caller*:: the original *samtools*/*bcftools* calling method (conflicts with *-m*) *-C, --constrain* 'alleles'|'trio':: 'alleles';; call genotypes given alleles. See also *-T, --targets-file*. 'trio';; call genotypes given the father-mother-child constraint. See also *-s, --samples* and *-n, --novel-rate*. *-m, --multiallelic-caller*:: alternative model for multiallelic and rare-variant calling designed to overcome known limitations in *-c* calling model (conflicts with *-c*) *-n, --novel-rate* 'float'[,...]:: likelihood of novel mutation for constrained *-C* 'trio' calling. The trio genotype calling maximizes likelihood of a particular combination of genotypes for father, mother and the child P(F=i,M=j,C=k) = P(unconstrained) * Pn + P(constrained) * (1-Pn). By providing three values, the mutation rate Pn is set explicitly for SNPs, deletions and insertions, respectively. If two values are given, the first is interpreted as the mutation rate of SNPs and the second is used to calculate the mutation rate of indels according to their length as Pn='float'*exp(-a-b*len), where a=22.8689, b=0.2994 for insertions and a=21.9313, b=0.2856 for deletions [pubmed:23975140]. If only one value is given, the same mutation rate Pn is used for SNPs and indels. *-p, --pval-threshold* 'float':: with *-c*, accept variant if P(ref|D) < 'float'. *-P, --prior* 'float':: expected substitution rate, or 0 to disable the prior. Only with *-m*. *-t, --targets* 'file'|'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-X, --chromosome-X*:: haploid output for male samples (requires PED file with *-s*) *-Y, --chromosome-Y*:: haploid output for males and skips females (requires PED file with *-s*) [[cnv]] === bcftools cnv '[OPTIONS]' 'FILE' Copy number variation caller, requires a VCF annotated with the Illumina's B-allele frequency (BAF) and Log R Ratio intensity (LRR) values. The HMM considers the following copy number states: CN 2 (normal), 1 (single-copy loss), 0 (complete loss), 3 (single-copy gain). ==== General Options: *-c, --control-sample* 'string':: optional control sample name. If given, pairwise calling is performed and the *-P* option can be used *-f, --AF-file* 'file':: read allele frequencies from a tab-delimited file with the columns CHR,POS,REF,ALT,AF *-o, --output-dir* 'path':: output directory *-p, --plot-threshold* 'float':: call *matplotlib* to produce plots for chromosomes with quality at least 'float', useful for visual inspection of the calls. With *-p 0*, plots for all chromosomes will be generated. If not given, a *matplotlib* script will be created but not called. *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --query-sample* 'string':: query sample name *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* ==== HMM Options: *-a, --aberrant* 'float'[,'float']:: fraction of aberrant cells in query and control. The hallmark of duplications and contaminations is the BAF value of heterozygous markers which is dependent on the fraction of aberrant cells. Sensitivity to smaller fractions of cells can be increased by setting *-a* to a lower value. Note however, that this comes at the cost of increased false discovery rate. *-b, --BAF-weight* 'float':: relative contribution from BAF *-d, --BAF-dev* 'float'[,'float']:: expected BAF deviation in query and control, i.e. the noise observed in the data. *-e, --err-prob* 'float':: uniform error probability *-l, --LRR-weight* 'float':: relative contribution from LRR. With noisy data, this option can have big effect on the number of calls produced. In truly random noise (such as in simulated data), the value should be set high (1.0), but in the presence of systematic noise when LRR are not informative, lower values result in cleaner calls (0.2). *-L, --LRR-smooth-win* 'int':: reduce LRR noise by applying moving average given this window size *-O, --optimize* 'float':: iteratively estimate the fraction of aberrant cells, down to the given fraction. Lowering this value from the default 1.0 to say, 0.3, can help discover more events but also increases noise *-P, --same-prob* 'float':: the prior probability of the query and the control sample being the same. Setting to 0 calls both independently, setting to 1 forces the same copy number state in both. *-x, --xy-prob* 'float':: the HMM probability of transition to another copy number state. Increasing this values leads to smaller and more frequent calls. [[concat]] === bcftools concat '[OPTIONS]' 'FILE1' 'FILE2' [...] Concatenate or combine VCF/BCF files. All source files must have the same sample columns appearing in the same order. Can be used, for example, to concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel VCF into one. The input files must be sorted by chr and position. The files must be given in the correct order to produce sorted VCF on output unless the *-a, --allow-overlaps* option is specified. With the --naive option, the files are concatenated without being recompressed, which is very fast.. *-a, --allow-overlaps*:: First coordinate of the next file can precede last record of the current file. *-c, --compact-PS*:: Do not output PS tag at each site, only at the start of a new phase set block. *-d, --rm-dups* 'snps'|'indels'|'both'|'all'|'exact':: Output duplicate records of specified type present in multiple files only once. Note that records duplicate within one file are not removed with this option, for that use *<>* instead. + In other words, the default behavior of the program is similar to unix "`cat`" in that when two files contain a record with the same position, that position will appear twice on output. With *-d*, every line that finds a matching record in another file will be printed only once. + Requires *-a, --allow-overlaps*. *-D, --remove-duplicates*:: Alias for *-d exact* *-f, --file-list* 'FILE':: Read file names from 'FILE', one file name per line. *-l, --ligate*:: Ligate phased VCFs by matching phase at overlapping haplotypes. Note that the option is intended for VCFs with perfect overlap, sites in overlapping regions present in one but missing in the other are dropped. *--ligate-force*:: Keep all sites and ligate even non-overlapping chunks and chunks with imperfect overlap *--ligate-warn*:: Drop sites in imperfect overlaps *--no-version*:: see *<>* *-n, --naive*:: Concatenate VCF or BCF files without recompression. This is very fast but requires that all files are of the same type (all VCF or all BCF) and have the same headers. This is because all tags and chromosome names in the BCF body rely on the order of the contig and tag definitions in the header. A header check compatibility is performed and the program throws an error if it is not safe to use the option. *--naive-force*:: Same as --naive, but header compatibility is not checked. Dangerous, use with caution. *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-q, --min-PQ* 'INT':: Break phase set if phasing quality is lower than 'INT' *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>*. Requires *-a, --allow-overlaps*. *-R, --regions-file* 'FILE':: see *<>*. Requires *-a, --allow-overlaps*. *--regions-overlap* '0'|'1'|'2':: see *<>* *--threads* 'INT':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. [[consensus]] === bcftools consensus '[OPTIONS]' 'FILE' Create consensus sequence by applying VCF variants to a reference fasta file. By default, the program will apply all ALT variants to the reference fasta to obtain the consensus sequence. Using the *--sample* (and, optionally, *--haplotype*) option will apply genotype (haplotype) calls from FORMAT/GT. Note that the program does not act as a primitive variant caller and ignores allelic depth information, such as INFO/AD or FORMAT/AD. For that, consider using the *setGT* plugin. *-a, --absent* 'CHAR':: replace positions absent from VCF with CHAR *-c, --chain* 'FILE':: write a chain file for liftover *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-f, --fasta-ref* 'FILE':: reference sequence in fasta format *-H, --haplotype* N|'R'|'A'|'I'|'LR'|'LA'|'SR'|'SA'|'NpIu':: choose which allele from the FORMAT/GT field to use (the codes are case-insensitive): 'N';; N={1,2,3,...}, the allele index within the genotype, regardless of phasing 'R';; the REF allele (in heterozygous genotypes) 'A';; the ALT allele (in heterozygous genotypes) 'I';; IUPAC code for all genotypes 'LR, LA';; the longer allele. If both have the same length, use the REF allele (LR), or the ALT allele (LA) 'SR, SA';; the shorter allele. If both have the same length, use the REF allele (SR), or the ALT allele (SA) 'NpIu';; N={1,2,3,...}, the allele index within genotype for phased genotypes and IUPAC code for unphased genotypes. For example, '1pIu' or '2pIu' Note that the *-H, --haplotype* option requires the *-s, --samples* option, unless exactly one sample is present in the VCF *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-I, --iupac-codes*:: output variants in the form of IUPAC ambiguity codes determined from FORMAT/GT fields. By default all samples are used and can be subset with *-s, --samples* and *-S, --samples-file*. Use *-s -* to ignore samples and use only the REF and ALT columns. NOTE: prior to version 1.17 the IUPAC codes were determined solely from REF,ALT columns and sample genotypes were not considered. *--mark-del* 'CHAR':: instead of removing sequence, insert character CHAR for deletions *--mark-ins* 'uc'|'lc'|'CHAR':: highlight inserted sequence in uppercase (uc), lowercase (lc), or a provided character CHAR, leaving the rest of the sequence as is *--mark-snv* 'uc'|'lc':: highlight substitutions in uppercase (uc), lowercase (lc), or a provided character CHAR, leaving the rest of the sequence as is *-m, --mask* 'FILE':: BED file or TAB file with regions to be replaced with N (the default) or as specified by the next *--mask-with* option. See discussion of *--regions-file* in *<>* for file format details. *--mask-with* 'CHAR'|'lc'|'uc':: replace sequence from *--mask* with CHAR, skipping overlapping variants, or change to lowercase (lc) or uppercase (uc) *-M, --missing* 'CHAR':: instead of skipping the missing genotypes, output the character CHAR (e.g. "?") *-o, --output* 'FILE':: write output to a file *--regions-overlap* '0'|'1'|'2':: how to treat VCF variants overlapping the target region in the fasta file: see *<>* *-s, --samples* 'LIST':: apply variants of the listed samples. See also the option *-I, --iupac-codes* *-S, --samples-file* 'FILE':: apply variants of the samples listed in the file. See also the option *-I, --iupac-codes* *Examples:* ---- # Apply variants present in sample "NA001", output IUPAC codes for hets bcftools consensus -i -s NA001 -f in.fa in.vcf.gz > out.fa # Create consensus for one region. The fasta header lines are then expected # in the form ">chr:from-to". Ignore samples and consider only the REF and ALT columns samtools faidx ref.fa 8:11870-11890 | bcftools consensus -s - in.vcf.gz -o out.fa # For more examples see http://samtools.github.io/bcftools/howtos/consensus-sequence.html ---- *Notes:*:: Masking options are applied in the following order 1. mask regions with *--mask-with* character if *--mask* is given. All overlapping VCF variants are ignored 2. replace sequence not mentioned in the VCF with the requested character if *--absent* is given 3. finally apply *--mark-del*, *--mark-ins*, *--mark-snv* masks [[convert]] === bcftools convert '[OPTIONS]' 'FILE' ==== VCF input options: *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'FILE':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* 'LIST':: see *<>* *-S, --samples-file* 'FILE':: see *<>* *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. ==== VCF output options: *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *--threads* 'INT':: see *<>* ==== GEN/SAMPLE conversion: *-G, --gensample2vcf* 'prefix' or 'gen-file','sample-file':: convert IMPUTE2 output to VCF. One of the ID columns ("SNP ID" or "rsID" in https://www.cog-genomics.org/plink/2.0/formats#gen) must be of the form "CHROM:POS_REF_ALT" to detect possible strand swaps. {nbsp} + When the *--vcf-ids* option is given, the other column (autodetected) is used to fill the ID column of the VCF. {nbsp} + See also *-g* and *--3N6* options. *-g, --gensample* 'prefix' or 'gen-file','sample-file':: convert from VCF to gen/sample format used by IMPUTE2 and SHAPEIT. The columns of .gen file format are ID1,ID2,POS,A,B followed by three genotype probabilities P(AA), P(AB), P(BB) for each sample. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". When the *--vcf-ids* option is given, the second column is set to match the ID column of the VCF. {nbsp} + See also *-G* and *--3N6* options. {nbsp} + The file .gen and .sample file format are: ---- .gen (with --3N6 --vcf-ids) --------------------------- chr1 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1 0 chr1 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 0 1 .gen (with --vcf-ids) --------------------------- 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1 0 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 0 1 .gen (the default) ------------------------------ 1:111485207_G_A 1:111485207_G_A 111485207 G A 0 1 0 0 1 0 1:111494194_C_T 1:111494194_C_T 111494194 C T 0 1 0 0 0 1 .sample ------- ID_1 ID_2 missing 0 0 0 sample1 sample1 0 sample2 sample2 0 ---- *--3N6*:: Expect/Create files in the 3*N+6 column format. This is the new .gen file format with the first column containing the chromosome name, see https://www.cog-genomics.org/plink/2.0/formats#gen *--tag* 'STRING':: tag to take values for .gen file: GT,PL,GL,GP *--sex* 'FILE':: output sex column in the sample file. The FILE format is ---- MaleSample M FemaleSample F ---- *--vcf-ids*:: output VCF IDs in the second column instead of CHROM:POS_REF_ALT ==== gVCF conversion: *--gvcf2vcf*:: convert gVCF to VCF, expanding REF blocks into sites. Note that the *-i* and *-e* options work differently with this switch. In this situation the filtering expressions define which sites should be expanded and which sites should be left unmodified, but all sites are printed on output. In order to drop sites, stream first through *<>*. *-f, --fasta-ref* 'file':: reference sequence in fasta format. Must be indexed with samtools faidx ==== HAP/SAMPLE conversion: *--hapsample2vcf* 'prefix' or 'hap-file','sample-file':: convert from hap/sample format to VCF. The columns of .hap file are similar to .gen file above, but there are only two haplotype columns per sample. Note that the first or the second column of the .hap file is expected to be in the form "CHR:POS_REF_ALT[_END]", with the _END being optional for defining the INFO/END tag when ALT is a symbolic allele. For example: ---- .hap (with --vcf-ids) --------------------- 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 1:111495231_A__111495784 rsID3 111495231 A 0 0 1 0 .hap (the default) ------------------ 1 1:111485207_G_A 111485207 G A 0 1 0 0 1 1:111495231_A__111495784 111495231 A 0 0 1 0 ---- *--hapsample* 'prefix' or 'hap-file','sample-file':: convert from VCF to hap/sample format used by IMPUTE2 and SHAPEIT. The columns of .hap file begin with ID,RSID,POS,REF,ALT. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". *--haploid2diploid*:: with *-h* option converts haploid genotypes to homozygous diploid genotypes. For example, the program will print '0 0' instead of the default '0 -'. This is useful for programs which do not handle haploid genotypes correctly. *--sex* 'FILE':: output sex column in the sample file. The FILE format is ---- MaleSample M FemaleSample F ---- *--vcf-ids*:: the second column of the .hap file holds the VCF ids, the first column is of the form "CHR:POS_REF_ALT[_END]". Without the option, the format follows https://www.cog-genomics.org/plink/2.0/formats#haps with ids (the second column) of the form "CHR:POS_REF_ALT[_END]" ==== HAP/LEGEND/SAMPLE conversion: *-H, --haplegendsample2vcf* 'prefix' or 'hap-file','legend-file','sample-file':: convert from hap/legend/sample format used by IMPUTE2 to VCF. See also *-h, --hapslegendsample* below. *-h, --haplegendsample* 'prefix' or 'hap-file','legend-file','sample-file':: convert from VCF to hap/legend/sample format used by IMPUTE2 and SHAPEIT. The columns of .legend file ID,POS,REF,ALT. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". The .sample file is quite basic at the moment with columns for population, group and sex expected to be edited by the user. For example: ---- .hap ----- 0 1 0 0 1 0 0 1 0 0 0 1 .legend ------- id position a0 a1 1:111485207_G_A 111485207 G A 1:111494194_C_T 111494194 C T .sample ------- sample population group sex sample1 sample1 sample1 2 sample2 sample2 sample2 2 ---- *--haploid2diploid*:: with *-h* option converts haploid genotypes to homozygous diploid genotypes. For example, the program will print '0 0' instead of the default '0 -'. This is useful for programs which do not handle haploid genotypes correctly. *--sex* 'FILE':: output sex column in the sample file. The FILE format is ---- MaleSample M FemaleSample F ---- *--vcf-ids*:: output VCF IDs instead of "CHROM:POS_REF_ALT". Note that this option can be used with *--haplegendsample* but not with *--haplegendsample2vcf*. ==== TSV conversion: *--tsv2vcf* 'file':: convert from TSV (tab-separated values) format (such as generated by 23andMe) to VCF. The input file fields can be tab- or space- delimited *-c, --columns* 'list':: comma-separated list of fields in the input file. In the current version, the fields CHROM, POS, ID, and AA or REF, ALT are expected and can appear in arbitrary order. Columns which should be ignored in the input file can be indicated by "-". The AA field lists alleles on the forward reference strand, for example "CC" or "CT" for diploid genotypes or "C" for haploid genotypes (sex chromosomes). Insertions and deletions are supported only with REF and ALT but not with AA. Missing data can be indicated with "--" or ".". *-f, --fasta-ref* 'file':: reference sequence in fasta format. Must be indexed with samtools faidx *-s, --samples* 'LIST':: list of sample names. See *<>* *-S, --samples-file* 'FILE':: file of sample names. See *<>* *Example:* ---- # Convert 23andme results into VCF bcftools convert -c ID,CHROM,POS,AA -s SampleName -f 23andme-ref.fa --tsv2vcf 23andme.txt -o out.vcf.gz # Convert tab-delimited file into a sites-only VCF (no genotypes), in this example first column to be ignored bcftools convert -c -,CHROM,POS,REF,ALT -f ref.fa --tsv2vcf calls.txt -o out.bcf ---- [[csq]] === bcftools csq '[OPTIONS]' 'FILE' Haplotype aware consequence predictor which correctly handles combined variants such as MNPs split over multiple VCF records, SNPs separated by an intron (but adjacent in the spliced transcript) or nearby frame-shifting indels which in combination in fact are not frame-shifting. The output VCF is annotated with INFO/BCSQ and FORMAT/BCSQ tag (configurable with the *-c* option). The latter is a bitmask of indexes to INFO/BCSQ, with interleaved haplotypes. See the usage examples below for using the %TBCSQ converter in *query* for extracting a more human readable form from this bitmask. The construction of the bitmask limits the number of consequences that can be referenced per sample in the FORMAT/BCSQ tags. By default this is 15, but if more are required, see the *--ncsq* option. Note that the program annotates only records with a functional consequence and intergenic regions will pass through unchanged. The program requires on input a VCF/BCF file, the reference genome in fasta format (*--fasta-ref*) and genomic features in the GFF3 format downloadable from the Ensembl website (*--gff-annot*), and outputs an annotated VCF/BCF file. Currently, only Ensembl GFF3 files are supported. By default, the input VCF should be phased. If phase is unknown, or only partially known, the *--phase* option can be used to indicate how to handle unphased data. Alternatively, haplotype aware calling can be turned off with the *--local-csq* option. If conflicting (overlapping) variants within one haplotype are detected, a warning will be emitted and predictions will be based on only the first variant in the analysis. Symbolic alleles are not supported. They will remain unannotated in the output VCF and are ignored for the prediction analysis. *-c, --custom-tag* 'STRING':: use this custom tag to store consequences rather than the default BCSQ tag *-B, --trim-protein-seq* 'INT':: abbreviate protein-changing predictions to maximum of INT aminoacids. For example, instead of writing the whole modified protein sequence with potentially hundreds of aminoacids, with *-B 1* only an abbreviated version such as '25E..329>25G..94' will be written. *--dump-gff* 'FILE':: dump the parsed GFF into a gzipped FILE. Intended for debugging purposes, shows how is the input GFF viewed by the program. *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-f, --fasta-ref* 'FILE':: reference sequence in fasta format (required) *--force*:: run even if some sanity checks fail. Currently the option enables skipping transcripts in malformatted GFFs with incorrect phase *-g, --gff-annot* 'FILE':: GFF3 annotation file (required), such as http://ftp.ensembl.org/pub/current_gff3/homo_sapiens/. The script *<>* can help with conversion from non-standard GFF formats. An example of a minimal working GFF file: ---- # The program looks for "CDS", "exon", "three_prime_UTR" and "five_prime_UTR" lines, # looks up their parent transcript (determined from the "Parent=transcript:" attribute), # the gene (determined from the transcript's "Parent=gene:" attribute), and the biotype # (the most interesting is "protein_coding"). # # Empty and commented lines are skipped, the following GFF columns are required # 1. chromosome # 2. IGNORED # 3. type (CDS, exon, three_prime_UTR, five_prime_UTR, gene, transcript, etc.) # 4. start of the feature (1-based) # 5. end of the feature (1-based) # 6. IGNORED # 7. strand (+ or -) # 8. phase (0, 1, 2 or .) # 9. semicolon-separated attributes (see below) # # Attributes required for # gene lines: # - ID=gene: # - biotype= # - Name= [optional] # # transcript lines: # - ID=transcript: # - Parent=gene: # - biotype= # # other lines (CDS, exon, five_prime_UTR, three_prime_UTR): # - Parent=transcript: # # Supported biotypes: # - see the function gff_parse_biotype() in bcftools/csq.c 1 ignored_field gene 21 2148 . - . ID=gene:GeneId;biotype=protein_coding;Name=GeneName 1 ignored_field transcript 21 2148 . - . ID=transcript:TranscriptId;Parent=gene:GeneId;biotype=protein_coding 1 ignored_field three_prime_UTR 21 2054 . - . Parent=transcript:TranscriptId 1 ignored_field exon 21 2148 . - . Parent=transcript:TranscriptId 1 ignored_field CDS 21 2148 . - 1 Parent=transcript:TranscriptId 1 ignored_field five_prime_UTR 210 2148 . - . Parent=transcript:TranscriptId ---- *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-l, --local-csq*:: switch off haplotype-aware calling, run localized predictions considering only one VCF record at a time *-n, --ncsq* 'INT':: maximum number of per-haplotype consequences to consider for each site. The INFO/BCSQ column includes all consequences, but only the first 'INT' will be referenced by the FORMAT/BCSQ fields. The default value is 15 which corresponds to one 32-bit integer per diploid sample, after accounting for values reserved by the BCF specification. Note that increasing the value leads to increased size of the output BCF. *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 't'|'b'|'u'|'z'|'v'[0-9]:: see *<>*. In addition, a custom tab-delimited plain text output can be printed ('t'). *-p, --phase* 'a'|'m'|'r'|'R'|'s':: how to handle unphased heterozygous genotypes: 'a';; take GTs as is, create haplotypes regardless of phase (0/1 -> 0|1) 'm';; merge all GTs into a single haplotype (0/1 -> 1, 1/2 -> 1) 'r';; require phased GTs, throw an error on unphased heterozygous GTs 'R';; create non-reference haplotypes if possible (0/1 -> 1|1, 1/2 -> 1|2) 's';; skip unphased heterozygous GTs *-q, --quiet*:: suppress warning messages *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'FILE':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* 'LIST':: samples to include or "-" to apply all variants and ignore samples *-S, --samples-file* 'FILE':: see *<>* *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *--unify-chr-names* '0'|'1':: Automatically detect and unify chromosome naming conventions in the GFF, fasta and VCF, such as "chrX" vs "X". The chromosome names in the output VCF will match that of the input VCF. The default is to attempt the automatic translation. *-v, --verbose* 'INT':: verbosity level (0-2) *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. *Examples:* ---- # Basic usage bcftools csq -f hs37d5.fa -g Homo_sapiens.GRCh37.82.gff3.gz in.vcf -Ob -o out.bcf # Extract the translated haplotype consequences. The following TBCSQ variations # are recognised: # %TBCSQ .. print consequences in all haplotypes in separate columns # %TBCSQ{0} .. print the first haplotype only # %TBCSQ{1} .. print the second haplotype only # %TBCSQ{*} .. print a list of unique consequences present in either haplotype bcftools query -f'[%CHROM\t%POS\t%SAMPLE\t%TBCSQ\n]' out.bcf ---- *Examples of BCSQ annotation:* ---- # Two separate VCF records at positions 2:122106101 and 2:122106102 # change the same codon. This UV-induced C>T dinucleotide mutation # has been annotated fully at the position 2:122106101 with # - consequence type # - gene name # - ensembl transcript ID # - coding strand (+ fwd, - rev) # - amino acid position (in the coding strand orientation) # - list of corresponding VCF variants # The annotation at the second position gives the position of the full # annotation BCSQ=missense|CLASP1|ENST00000545861|-|1174P>1174L|122106101G>A+122106102G>A BCSQ=@122106101 # A frame-restoring combination of two frameshift insertions C>CG and T>TGG BCSQ=@46115084 BCSQ=inframe_insertion|COPZ2|ENST00000006101|-|18AGRGP>18AQAGGP|46115072C>CG+46115084T>TGG # Stop gained variant BCSQ=stop_gained|C2orf83|ENST00000264387|-|141W>141*|228476140C>T # The consequence type of a variant downstream from a stop are prefixed with * BCSQ=*missense|PER3|ENST00000361923|+|1028M>1028T|7890117T>C ---- *Supported consequence types* ---- 3_prime_utr 5_prime_utr coding_sequence feature_elongation frameshift inframe_altering inframe_deletion inframe_insertion intergenic intron missense non_coding splice_acceptor splice_donor splice_region start_lost start_retained stop_gained stop_lost stop_retained synonymous ---- See also https://ensembl.org/info/genome/variation/prediction/predicted_data.html [[filter]] === bcftools filter '[OPTIONS]' 'FILE' Apply fixed-threshold filters. *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-g, --SnpGap* 'INT'[:'indel','mnp','bnd','other','overlap']:: filter SNPs within 'INT' base pairs of an indel or other other variant type. The following example demonstrates the logic of *--SnpGap* '3' applied on a deletion and an insertion: ---- The SNPs at positions 1 and 7 are filtered, positions 0 and 8 are not: 0123456789 ref .G.GT..G.. del .A.G-..A.. Here the positions 1 and 6 are filtered, 0 and 7 are not: 0123-456789 ref .G.G-..G.. ins .A.GT..A.. ---- *-G, --IndelGap* 'INT':: filter clusters of indels separated by 'INT' or fewer base pairs allowing only one to pass. The following example demonstrates the logic of *--IndelGap* '2' applied on a deletion and an insertion: ---- The second indel is filtered: 012345678901 ref .GT.GT..GT.. del .G-.G-..G-.. And similarly here, the second is filtered: 01 23 456 78 ref .A-.A-..A-.. ins .AT.AT..AT.. ---- *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *--mask* \[^]'REGION':: Soft filter regions, prepepend "^" to negate. Requires *-s, --soft-filter*. *-M, --mask-file* \[^]'FILE':: Soft filter regions listed in a file, "^" to negate. Requires *-s, --soft-filter*. *--mask-overlap* '0'|'1'|'2':: Same as *--regions-overlap* but for *--mask/--mask-file*. See *<>*. [1] *-m, --mode* ['+x']:: define behaviour at sites with existing FILTER annotations. The default mode replaces existing filters of failed sites with a new FILTER string while leaving sites which pass untouched when non-empty and setting to "PASS" when the FILTER string is absent. The "\+" mode appends new FILTER strings of failed sites instead of replacing them. The "x" mode resets filters of sites which pass to "PASS". Modes "+" and "x" can both be set. *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --soft-filter* 'STRING'|'+':: annotate FILTER column with 'STRING' or, with '+', a unique filter name generated by the program ("Filter%d"). Applies to records that do not meet filter expression. *-S, --set-GTs* '.'|'0':: set genotypes of failed samples to missing value ('.') or reference allele ('0') *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *--threads* 'INT':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. [[gtcheck]] === bcftools gtcheck ['OPTIONS'] [*-g* 'genotypes.vcf.gz'] 'query.vcf.gz' Checks sample identity. The program can operate in two modes. If the *-g* option is given, the identity of samples from 'query.vcf.gz' is checked against the samples in the *-g* file. Without the *-g* option, multi-sample cross-check of samples in 'query.vcf.gz' is performed. Note that the interpretation of the discordance score depends on the options provided (specifically *-e* and *-u*) and on the available annotations (FORMAT/PL vs FORMAT/GT). The discordance score can be interpreted as the number of mismatching genotypes only if GT-vs-GT matching is performed. *--distinctive-sites* 'NUM[,MEM[,DIR]]':: Find sites that can distinguish between at least NUM sample pairs. If the number is smaller or equal to 1, it is interpreted as the fraction of pairs. The optional MEM string sets the maximum memory used for in-memory sorting and DIR is the temporary directory for external sorting. This option requires also *--pairs* to be given. *--dry-run*:: Stop after first record to estimate required time. *-e, --exclude* ['qry'|'gt']:'EXPRESSION':: Exclude sites from query file ('qry:') or genotype file ('gt:') for which 'EXPRESSION' is true. For valid expressions see *<>*. *-E, --error-probability* 'INT':: Interpret genotypes and genotype likelihoods probabilistically. The value of 'INT' represents genotype quality when GT tag is used (e.g. Q=30 represents one error in 1,000 genotypes and Q=40 one error in 10,000 genotypes) and is ignored when PL tag is used (in that case an arbitrary non-zero integer can be provided). {nbsp} + {nbsp} + If *-E* is set to 0, the discordance score can be interpreted as the number of mismatching genotypes, but only in the GT-vs-GT matching mode. See the *-u, --use* option below for additional notes and caveats. {nbsp} + {nbsp} + If performance is an issue, set *-E 0* for faster run times but less accurate results. {nbsp} + {nbsp} + Note that in previous versions of bcftools (<=1.18), this option used to be a smaller case *-e*. It changed to make room for the filtering option *-e, --exclude* to stay consistent across other commands. *-g, --genotypes* 'FILE':: VCF/BCF file with reference genotypes to compare against *-H, --homs-only*:: Homozygous genotypes only, useful with low coverage data (requires *-g, --genotypes*) *-i, --include* ['qry'|'gt']:'EXPRESSION':: Include sites from query file ('qry:') or genotype file ('gt:') for which 'EXPRESSION' is true. For valid expressions see *<>*. *--n-matches* 'INT':: Print only top INT matches for each sample, 0 for unlimited. Use negative value to sort by HWE probability rather than the number of discordant sites. Note that average score is used to determine the top matches, not absolute values. *--no-HWE-prob*:: Disable calculation of HWE probability to reduce memory requirements with comparisons between very large number of sample pairs. *-o, --output* 'FILE':: Write to 'FILE' rather than to standard output, where it is written by default. *-O, --output-type* 't'|'z':: Write a plain ('t') or compressed ('z') text tab-delimited output. *-p, --pairs* 'LIST':: A comma-separated list of sample pairs to compare. When the *-g* option is given, the first sample must be from the query file, the second from the *-g* file, third from the query file etc (qry,gt[,qry,gt..]). Without the *-g* option, the pairs are created the same way but both samples are from the query file (qry,qry[,qry,qry..]) *-P, --pairs-file* 'FILE':: A file with tab-delimited sample pairs to compare. The first sample in the pair must come from the query file, the second from the genotypes file when *-g* is given *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: Restrict to comma-separated list of regions, see *<>* *-R, --regions-file' 'FILE':: Restrict to regions listed in a file, see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* ['qry'|'gt']:'LIST': List of query samples or *-g* samples. If neither *-s* nor *-S* are given, all possible sample pair combinations are compared *-S, --samples-file* ['qry'|'gt']:'FILE' File with the query or *-g* samples to compare. If neither *-s* nor *-S* are given, all possible sample pair combinations are compared *-t, --targets* 'file':: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-u, --use* 'TAG1'[,'TAG2']:: specifies which tag to use in the query file ('TAG1') and the *-g* ('TAG2') file. By default, the PL tag is used in the query file and, when available, the GT tags in the *-g* file. {nbsp} + {nbsp} + Note that when the requested tag is not available, the program will attempt to use the other tag. The output includes the number of sites that were matched by the four possible modes (for example GT-vs-GT or GT-vs-PL). *Examples:* ---- # Check discordance of all samples from B against all samples in A bcftools gtcheck -g A.bcf B.bcf # Limit comparisons to the given list of samples bcftools gtcheck -s gt:a1,a2,a3 -s qry:b1,b2 -g A.bcf B.bcf # Compare only two pairs a1,b1 and a1,b2 bcftools gtcheck -p a1,b1,a1,b2 -g A.bcf B.bcf ---- // ==== Output files format: // CN, Discordance;; // Pairwise discordance for all sample pairs is calculated as // ---- // \sum_s { min_G { PL_a(G) + PL_b(G) } }, // ---- // ;; // where the sum runs over all sites 's' and 'G' is the the most likely // genotype shared by both samples 'a' and 'b'. When PL field is not // present, a constant value '99' is used for the unseen genotypes. With // *-G*, the value '1' can be used instead; the discordance value then // gives exactly the number of differing genotypes. // // ERR, error rate;; // Pairwise error rate calculated as number of differences divided // by the total number of comparisons. // // CLUSTER, TH, DOT;; // In presence of multiple samples, related samples and outliers can be // identified by clustering samples by error rate. A simple hierarchical // clustering based on minimization of standard deviation is used. This is // useful to detect sample swaps, for example in situations where one // sample has been sequenced in multiple runs. // MD, Maximum Deviation;; // The maximum absolute deviation from average score of the sample // most dissimilar to the rest. [[head]] === bcftools head ['OPTIONS'] ['FILE'] By default, prints all headers from the specified input file to standard output in VCF format. The input file may be in VCF or BCF format; if no 'FILE' is specified, standard input will be read. With appropriate options, only some of the headers and/or additionally some of the variant records will be printed. The *bcftools head* command outputs VCF headers almost exactly as they appear in the input file: it may add a `##FILTER=` header if not already present, but it never adds version or command line information itself. ==== Options: *-h, --header* 'INT':: Display only the first 'INT' header lines. By default, all header lines are displayed. *-n, --records* 'INT':: Also display the first 'INT' variant records. By default, no variant records are displayed. *-s, --samples* 'INT':: Display the first 'INT' variant records including the last #CHROM header line with samples. Running with *-s 0* alone outputs the #CHROM header line only. Note that the list of samples, with each sample per line, can be obtained with `bcftools query` using the option *-l, --list-samples*. [[index]] === bcftools index ['OPTIONS'] 'in.bcf'|'in.vcf.gz' Creates index for bgzip compressed VCF/BCF files for random access. CSI (coordinate-sorted index) is created by default. The CSI format supports indexing of chromosomes up to length 2^31. TBI (tabix index) index files, which support chromosome lengths up to 2^29, can be created by using the '-t/--tbi' option or using the 'tabix' program packaged with htslib. When loading an index file, bcftools will try the CSI first and then the TBI. ==== Indexing options: *-c, --csi*:: generate CSI-format index for VCF/BCF files [default] *-f, --force*:: overwrite index if it already exists *-m, --min-shift 'INT'*:: set minimal interval size for CSI indices to 2^INT; default: 14 *-o, --output 'FILE'*:: output file name. If not set, then the index will be created using the input file name plus a '.csi' or '.tbi' extension *-t, --tbi*:: generate TBI-format index for VCF files *--threads* 'INT':: see *<>* ==== Stats options: *-a, --all*:: Used in conjunction with *-s, --stats*, print per contig stats for all contigs, even those with zero records and those for which no stats are recorded in the index file (shown as '.'). *-n, --nrecords*:: print the number of records based on the CSI or TBI index files *-s, --stats*:: Print per contig stats based on the CSI or TBI index files. Output format is three tab-delimited columns listing the contig name, contig length ('.' if unknown) and number of records for the contig. Contigs with zero records are not printed by default. [[isec]] === bcftools isec ['OPTIONS'] 'A.vcf.gz' 'B.vcf.gz' [...] Creates intersections, unions and complements of VCF files. Depending on the options, the program can output records from one (or more) files which have (or do not have) corresponding records with the same position in the other files. *-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none':: see *<>* *-C, --complement*:: output positions present only in the first file but missing in the others *-e, --exclude* '-'|'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. If *-e* (or *-i*) appears only once, the same filtering expression will be applied to all input files. Otherwise, *-e* or *-i* must be given for each input file. To indicate that no filtering should be performed on a file, use "-" in place of 'EXPRESSION', as shown in the example below. For valid expressions see *<>*. *-f, --apply-filters* 'LIST':: see *<>* *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. See discussion of *-e, --exclude* above. *-f, --file-list* 'FILE':: Read file names from 'FILE', one file name per line. *-n, --nfiles* \[+-=]'INT'|~'BITMAP':: output positions present in this many (=), this many or more (+), this many or fewer (-), or the exact same (~) files *-o, --output* 'FILE':: see *<>*. When several files are being output, their names are controlled via *-p* instead. *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-p, --prefix* 'DIR':: if given, subset each of the input files accordingly. See also *-w*. *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-w, --write* 'LIST':: comma-separated list of input files to output given as 1-based indices. With *-p* and no *-w*, all files are written. *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and defaults to tbi for vcf.gz and csi for bcf. This is done automatically with the *-p* option if the output format is compressed. ==== Examples: Create intersection and complements of two sets saving the output in dir/* ---- bcftools isec -p dir A.vcf.gz B.vcf.gz ---- Filter sites in A (require INFO/MAF>=0.01) and B (require INFO/dbSNP) but not in C, and create an intersection, including only sites which appear in at least two of the files after filters have been applied ---- bcftools isec -e'MAF<0.01' -i'dbSNP=1' -e- A.vcf.gz B.vcf.gz C.vcf.gz -n +2 -p dir ---- Extract and write records from A shared by both A and B using exact allele match ---- bcftools isec -p dir -n=2 -w1 A.vcf.gz B.vcf.gz ---- Extract records private to A or B comparing by position only ---- bcftools isec -p dir -n-1 -c all A.vcf.gz B.vcf.gz ---- Print a list of records which are present in A and B but not in C and D ---- bcftools isec -n~1100 -c all A.vcf.gz B.vcf.gz C.vcf.gz D.vcf.gz ---- [[merge]] === bcftools merge ['OPTIONS'] 'A.vcf.gz' 'B.vcf.gz' [...] Merge multiple VCF/BCF files from non-overlapping sample sets to create one multi-sample file. For example, when merging file 'A.vcf.gz' containing samples 'S1', 'S2' and 'S3' and file 'B.vcf.gz' containing samples 'S3' and 'S4', the output file will contain five samples named 'S1', 'S2', 'S3', '2:S3' and 'S4'. Note that it is responsibility of the user to ensure that the sample names are unique across all files. If they are not, the program will exit with an error unless the option *--force-samples* is given. The sample names can be also given explicitly using the *--print-header* and *--use-header* options. Note that only records from different files can be merged, never from the same file. For "vertical" merge take a look at *<>* or *<> -m* instead. *--force-no-index*:: synonymous to *--no-index* *--force-samples*:: if the merged files contain duplicate samples names, proceed anyway. Duplicate sample names will be resolved by prepending the index of the file as it appeared on the command line to the conflicting sample name (see '2:S3' in the above example). *--force-single*:: run even if only one file is given on input *--print-header*:: print only merged header and exit *--use-header* 'FILE':: use the VCF header in the provided text 'FILE' *-0 --missing-to-ref*:: assume genotypes at missing sites are 0/0 *-f, --apply-filters* 'LIST':: see *<>* *-F, --filter-logic* 'x'|'+':: Set the output record to PASS if any of the inputs is PASS ('x'), or apply all filters ('+'), which is the default. *-g, --gvcf* '-'|'FILE':: merge gVCF blocks, INFO/END tag is expected. If the reference fasta file 'FILE' is not given and the dash ('-') is given, unknown reference bases generated at gVCF block splits will be substituted with N's. The *--gvcf* option uses the following default INFO rules: *-i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max* and the following missing rules: *-M PL:max,AD:0*. *-i, --info-rules* '-'|'TAG:METHOD'[,...]:: Rules for merging INFO fields (scalars or vectors) or '-' to disable the default rules. 'METHOD' is one of 'sum', 'avg', 'min', 'max', 'join'. Default is 'DP:sum,DP4:sum' if these fields exist in the input files. Fields with no specified rule will take the value from the first input file. The merged QUAL value is currently set to the maximum. This behaviour is not user controllable at the moment. *-l, --file-list* 'FILE':: Read file names from 'FILE', one file name per line. *-L, --local-alleles* 'INT':: Sites with many alternate alleles can require extremely large storage space which can exceed the 2GB size limit representable by BCF. This is caused by Number=G tags (such as FORMAT/PL) which store a value for each combination of reference and alternate alleles. The *-L, --local-alleles* option allows replacement of such tags with a localized tag (FORMAT/LPL) which only includes a subset of alternate alleles relevant for that sample. A new FORMAT/LAA tag is added which lists 1-based indices of the alternate alleles relevant (local) for the current sample. The number 'INT' gives the maximum number of alternate alleles that can be included in the PL tag. The default value is 0 which disables the feature and outputs values for all alternate alleles. *-m, --merge* 'snps'|'indels'|'both'|'snp-ins-del'|'all'|'none'|'id'[,'*']:: The option controls what types of multiallelic records can be created. If single asterisk '\*' is appended, the unobserved allele '<*>' or '' will be removed at variant sites; if two asterisks '**' are appended, the unobserved allele will be removed all sites. ---- -m none .. no new multiallelics, output multiple records instead -m snps .. allow multiallelic SNP records -m indels .. allow multiallelic indel records -m both .. both SNP and indel records can be multiallelic -m both,* .. same as above but remove <*> (or ) from variant sites -m both,** .. same as above but remove <*> (or ) at all sites -m all .. SNP records can be merged with indel records -m snp-ins-del .. allow multiallelic SNVs, insertions, deletions, but don't mix them -m id .. merge by ID ---- *-M, --missing-rules* '-'|'TAG:METHOD'[,...]:: Rules for merging vector tags at multiallelic sites. When input files have different alternate alleles, vector fields pertaining to unobserved alleles are set to missing ('.') by default. The 'METHOD' is one of '.' (the default, use missing values), 'NUMBER' (use a constant value, e.g. 0), 'max' (the maximum value observed for other alleles in the sample). When *--gvcf* option is set, the rule *-M PL:max,AD:0* is implied. This can be overridden with providing *-M -* or *-M PL:.,AD:.*. Note that if the unobserved allele is explicitly present as '<*>' or '', then its corresponding value will be used regardless of *-M* settings. *--no-index*:: the option allows files to be merged without indexing them first. In order for this option to work, the user must ensure that the input files have chromosomes in the same order and consistent with the order of sequences in the VCF header. *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *--threads* 'INT':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. [[mpileup]] === bcftools mpileup ['OPTIONS'] *-f* 'ref.fa' 'in.bam' ['in2.bam' [...]] Generate VCF or BCF containing genotype likelihoods for one or multiple alignment (BAM or CRAM) files. This is based on the original *samtools mpileup* command (with the *-v* or *-g* options) producing genotype likelihoods in VCF or BCF format, but not the textual pileup output. The *mpileup* command was transferred to bcftools in order to avoid errors resulting from use of incompatible versions of samtools and bcftools when using in the mpileup+bcftools call pipeline. Individuals are identified from the SM tags in the @RG header lines. Multiple individuals can be pooled in one alignment file, also one individual can be separated into multiple files. If sample identifiers are absent, each input file is regarded as one sample. Note that there are two orthogonal ways to specify locations in the input file; via *-r* 'region' and *-t* 'positions'. The former uses (and requires) an index to do random access while the latter streams through the file contents filtering out the specified regions, requiring no index. The two may be used in conjunction. For example a BED file containing locations of genes in chromosome 20 could be specified using *-r 20 -t chr20.bed*, meaning that the index is used to find chromosome 20 and then it is filtered for the regions listed in the BED file. Also note that the *-r* option can be much slower than *-t* with many regions and can require more memory when multiple regions and many alignment files are processed. ==== Input options *-6, --illumina1.3+*:: Assume the quality is in the Illumina 1.3+ encoding. *-A, --count-orphans*:: Include anomalous read pairs in variant calling, i.e. reads with flag PAIRED but not PROPER_PAIR set. By default such reads are discarded. *-b, --bam-list* 'FILE':: List of input alignment files, one file per line [null] *-B, --no-BAQ*:: Disable probabilistic realignment for the computation of base alignment quality (BAQ). BAQ is the Phred-scaled probability of a read base being misaligned. Applying this option greatly helps to reduce false SNPs caused by misalignments. *-C, --adjust-MQ* 'INT':: Coefficient for downgrading mapping quality for reads containing excessive mismatches. Mismatches are counted as a proportion of the number of aligned bases ("M", "X" or "=" CIGAR operations), along with their quality, to derive an upper-bound of the mapping quality. Original mapping qualities lower than this are left intact, while higher ones are capped at the new adjusted score. + The exact formula is complex and likely tuned to specific instruments and specific alignment tools, so this option is disabled by default (indicated as having a zero value). Variables in the formulae and their meaning are defined below. + ---- Variable Meaning / formula M The number of matching CIGAR bases (operation "M", "X" or "="). X The number of substitutions with quality >= 13. SubQ The summed quality of substitution bases included in X, capped at a maximum of quality 33 per mismatching base. ClipQ The summed quality of soft-clipped or hard-clipped bases. This has no minimum or maximum quality threshold per base. For hard-clipped bases the per-base quality is taken as 13. T SubQ - 10 * log10(M^X / X!) + ClipQ/5 Cap MAX(0, INT * sqrt((INT - T) / INT)) ---- + Some notes on the impact of this. + - As the number of mismatches increases, the mapping quality cap reduces, eventually resulting in discarded alignments. - High quality mismatches reduces the cap faster than low quality mismatches. - The starting INT value also acts as a hard cap on mapping quality, even when zero mismatches are observed. - Indels have no impact on the mapping quality. + The intent of this option is to work around aligners that compute a mapping quality using a local alignment without having any regard to the degree of clipping required or consideration of potential contamination or large scale insertions with respect to the reference. A record may align uniquely and have no close second match, but having a high number of mismatches may still imply that the reference is not the correct site. + However we do not recommend use of this parameter unless you fully understand the impact of it and have determined that it is appropriate for your sequencing technology. *-D, --full-BAQ*:: Run the BAQ algorithm on all reads, not just those in problematic regions. This matches the behaviour for Bcftools 1.12 and earlier. + By default mpileup uses heuristics to decide when to apply the BAQ algorithm. Most sequences will not be BAQ adjusted, giving a CPU time closer to --no-BAQ, but it will still be applied in regions with suspected problematic alignments. This has been tested to work well on single sample data with even allele frequency, but the reliability is unknown for multi-sample calling and for low allele frequency variants so full BAQ is still recommended in those scenarios. *-d, --max-depth* 'INT':: At a position, read maximally 'INT' reads per input file. Note that the original *samtools mpileup* command had a minimum value of '8000/n' where 'n' was the number of input files given to mpileup. This means that in *samtools mpileup* the default was highly likely to be increased and the *-d* parameter would have an effect only once above the cross-sample minimum of 8000. This behavior was problematic when working with a combination of single- and multi-sample bams, therefore in *bcftools mpileup* the user is given the full control (and responsibility), and an informative message is printed instead [250] *-E, --redo-BAQ*:: Recalculate BAQ on the fly, ignore existing BQ tags *-f, --fasta-ref* 'FILE':: The *faidx*-indexed reference file in the FASTA format. The file can be optionally compressed by *bgzip*. Reference is required by default unless the *--no-reference* option is set [null] *--no-reference*:: Do not require the *--fasta-ref* option. *-G, --read-groups* [^]'FILE':: list of read groups to include or exclude if prefixed with "^". One read group per line. This file can also be used to assign new sample names to read groups by giving the new sample name as a second white-space-separated field, like this: "read_group_id new_sample_name". If the read group name is not unique, also the bam file name can be included: "read_group_id file_name sample_name". If all reads from the alignment file should be treated as a single sample, the asterisk symbol can be used: "* file_name sample_name". Alignments without a read group ID can be matched with "?". *NOTE:* The meaning of *bcftools mpileup -G* is the opposite of *samtools mpileup -G*. ---- RG_ID_1 RG_ID_2 SAMPLE_A RG_ID_3 SAMPLE_A RG_ID_4 SAMPLE_B RG_ID_5 FILE_1.bam SAMPLE_A RG_ID_6 FILE_2.bam SAMPLE_A * FILE_3.bam SAMPLE_C ? FILE_3.bam SAMPLE_D ---- *--indels-2.0*:: A new EXPERIMENTAL indel calling model which aims to address some known deficiencies of the current indel calling algorithm. Specifically, it uses diploid reference consensus sequence. Note that in the current version it has the potential to increase sensitivity but at the cost of decreased specificity. Only works with short-read sequencing technologies. *--indels-cns*:: Another EXPERIMENTAL indel calling method, predating indels-2.0 in PR form, but merged more recently. It also uses a diploid reference consensus, but with added parameters and heuristics to optimise for a variety of sequencing platforms. This is usually faster and more accurate than the default caller and --indels-2.0, but has not been tested on non-diploid samples and samples without approximately even allele frequency. *--no-indels-cns*:: May be used to turn off --indels-cns mode when using one of the newer profiles that has this enabled by default. *-q, -min-MQ* 'INT':: Minimum mapping quality for an alignment to be used [0] *-Q, --min-BQ* 'INT':: Minimum base quality for a base to be considered [13] *--max-BQ* 'INT':: Caps the base quality to a maximum value [60]. This can be particularly useful on technologies that produce overly optimistic high qualities, leading to too many false positives or incorrect genotype assignments. *-r, --regions* 'CHR'|'CHR:POS'|'CHR:FROM-TO'|'CHR:FROM-'[,...]:: Only generate mpileup output in given regions. Requires the alignment files to be indexed. If used in conjunction with -l then considers the intersection; see *<>* *-R, --regions-file* 'FILE':: As for *-r, --regions*, but regions read from FILE; see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *--ignore-RG*:: Ignore RG tags. Treat all reads in one alignment file as one sample. *--ls, --skip-all-set*:: Skip reads with all of the FLAG bits set [null] *--ns, --skip-any-set*:: Skip reads with any of the FLAG bits set. This option replaces and is synonymous to the deprecated *--ff, --excl-flags* [UNMAP,SECONDARY,QCFAIL,DUP] *--lu, --skip-all-unset*:: Skip reads with all of the FLAG bits unset. This option replaces and is synonymous to the deprecated *--rf, --incl-flags* [null] *--nu, --skip-any-unset*:: Skip reads with any of the FLAG bits unset [null] *-s, --samples* [^]'LIST':: list of sample names. See *<>* *-S, --samples-file* [^]'FILE':: file of sample names to include or exclude if prefixed with "^". One sample per line. This file can also be used to rename samples by giving the new sample name as a second white-space-separated column, like this: "old_name new_name". If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\ a\ good\ sample\ name". *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-x, --ignore-overlaps*:: Disable read-pair overlap detection. *--seed* 'INT':: Set the random number seed used when sub-sampling deep regions [0]. ==== Output options *-a, --annotate* 'LIST':: Comma-separated list of FORMAT and INFO tags to output. (case-insensitive, the "FORMAT/" prefix is optional, and use "?" to list available annotations on the command line) [null]: ---- FORMAT/AD .. Allelic depth (Number=R,Type=Integer) FORMAT/ADF .. Allelic depths on the forward strand (Number=R,Type=Integer) FORMAT/ADR .. Allelic depths on the reverse strand (Number=R,Type=Integer) FORMAT/DP .. Number of high-quality bases (Number=1,Type=Integer) FORMAT/SP .. Phred-scaled strand bias P-value (Number=1,Type=Integer) FORMAT/SCR .. Number of soft-clipped reads (Number=1,Type=Integer) INFO/AD .. Total allelic depth (Number=R,Type=Integer) INFO/ADF .. Total allelic depths on the forward strand (Number=R,Type=Integer) INFO/ADR .. Total allelic depths on the reverse strand (Number=R,Type=Integer) INFO/SCR .. Number of soft-clipped reads (Number=1,Type=Integer) FORMAT/DV .. Deprecated in favor of FORMAT/AD; Number of high-quality non-reference bases, (Number=1,Type=Integer) FORMAT/DP4 .. Deprecated in favor of FORMAT/ADF and FORMAT/ADR; Number of high-quality ref-forward, ref-reverse, alt-forward and alt-reverse bases (Number=4,Type=Integer) FORMAT/DPR .. Deprecated in favor of FORMAT/AD; Number of high-quality bases for each observed allele (Number=R,Type=Integer) INFO/DPR .. Deprecated in favor of INFO/AD; Number of high-quality bases for each observed allele (Number=R,Type=Integer) ---- *-g, --gvcf* 'INT'[,...]:: output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers. For example, passing '5,15' will group sites into two types of gVCF blocks, the first with minimum per-sample DP from the interval [5,15) and the latter with minimum depth 15 or more. In this example, sites with minimum per-sample depth less than 5 will be printed as separate records, outside of gVCF blocks. *--no-version*:: see *<>* *-o, --output* 'FILE':: Write output to 'FILE', rather than the default of standard output. (The same short option is used for both *--open-prob* and *--output*. If *-o*'s argument contains any non-digit characters other than a leading + or - sign, it is interpreted as *--output*. Usually the filename extension will take care of this, but to write to an entirely numeric filename use *-o ./123* or *--output 123*.) *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *--threads* 'INT':: see *<>* *-U, --mwu-u*:: The the previous Mann-Whitney U test score from version 1.12 and earlier. This is a probability score, but importantly it folds probabilities above or below the desired score into the same P. The new Mann-Whitney U test score is a "Z score", expressing the score as the number of standard deviations away from the mean (with zero being matching the mean). It keeps both positive and negative values. This can be important for some tests where errors are asymmetric. This option changes the INFO field names produced back to the ones used by the earlier Bcftools releases. For excample BQBZ becomes BQB. *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. ==== Options for SNP/INDEL genotype likelihood computation *-X, --config* 'STR':: Specify a platform specific configuration profile. Specifying the profile as "list" will list the available profile names and the parameters they change. There are profiles named after a release, which should be used if you wish to ensure forward compatibility of results. The non-versioned names (eg "illumina") will always point to the most recent set of parameters for that instrument type. The current values are: 1.12 -Q13 -h100 -m1 bgi bgi-1.20 --indels-cns -B --indel-size 80 -F0.1 --indel-bias 0.9 --seqq-offset 120 illumina-1.18 [ default values ] illumina illumina-1.20 --indels-cns --seqq-offset 125 ont -B -Q5 --max-BQ 30 -I ont-sup ont-sup-1.20 --indels-cns -B -Q1 --max-BQ 35 --delta-BQ 99 -F0.2 -o15 -e1 -h110 --del-bias 0.4 --indel-bias 0.7 --poly-mqual --seqq-offset 130 --indel-size 80 pacbio-ccs-1.18 -D -Q5 --max-BQ 50 -F0.1 -o25 -e1 -M99999 pacbio-ccs pacbio-ccs-1.20 --indels-cns -B -Q5 --max-BQ 50 -F0.1 -o25 -e1 -h300 --delta-BQ 10 --del-bias 0.4 --poly-mqual --indel-bias 0.9 --seqq-offset 118 --indel-size 80 --score-vs-ref 0.7 ultima ultima-1.20 --indels-cns -B -Q1 --max-BQ 30 --delta-BQ 10 -F0.15 -o20 -e10 -h250 --del-bias 0.3 --indel-bias 0.7 --poly-mqual --seqq-offset 140 --score-vs-ref 0.3 --indel-size 80 *--ar, --ambig-reads* 'drop'|'incAD'|'incAD0':: What to do with ambiguous indel reads that do not span an entire short tandem repeat region: discard ambiguous reads from calling and do not increment high-quality AD depth counters ('drop'), exclude from calling but increment AD counters proportionally ('incAD'), exclude from calling and increment the first value of the AD counter ('incAD0') ['drop'] *-e, --ext-prob* 'INT':: Phred-scaled gap extension sequencing error probability. Reducing 'INT' leads to longer indels [20] *-F, --gap-frac* 'FLOAT':: Minimum fraction of gapped reads [0.002] *-h, --tandem-qual* 'INT':: Coefficient for modeling homopolymer errors. Given an 'l'-long homopolymer run, the sequencing error of an indel of size s is modeled as 'INT'*s/l [500] Increasing this informs the caller that indels in long homopolymers are more likely genuine and less likely to be sequencing artifacts. Hence increasing tandem-qual will have higher recall and lower precision. Bcftools 1.12 and earlier had a default of 100, which was tuned around more error prone instruments. Note changing this may have a minor impact on SNP calling too. For maximum SNP calling accuracy, it may be preferable to adjust this lower again, although this will adversely affect indels. *--indel-bias* 'FLOAT':: Skews the indel scores up or down, trading recall (low false-negative) vs precision (low false-positive) [1.0]. In Bcftools 1.12 and earlier this parameter didn't exist, but had an implied value of 1.0. If you are planning to do heavy filtering of variants, selecting the best quality ones only (favouring precision over recall), it is advisable to set this lower (such as 0.75) while higher depth samples or where you favour recall rates over precision may work better with a higher value such as 2.0. *--del-bias* 'FLOAT':: Skews the likelihood of deletions over insertions. Defaults to an even distribution value of 1.0. Lower values imply a higher rate of false positive deletions (meaning candidate deletions are less likely to be real). *--indel-size* 'INT':: Indel window size to use when assessing the quality of candidate indels. Note that although the window size approximately corresponds to the maximum indel size considered, it is not an exact threshold [110] *--seqq-offset* 'INT':: Tunes the importance of indel sequence quality per depth. The final "seqQ" quality used is "offset - 5*MIN(depth,20)". [120] *--poly-mqual*:: Use the lowest quality value within a homopolymer run, instead of the quality immediately adjacent to the indel. This may be important for unclocked instruments, particularly ones with a flow chemistry where runs of bases of identical type are incorporated together. *-I, --skip-indels*:: Do not perform INDEL calling *-L, --max-idepth* 'INT':: Skip INDEL calling if the average per-sample depth is above 'INT' [250] *-m, --min-ireads* 'INT':: Minimum number gapped reads for indel candidates 'INT' [1] *-M, --max-read-len* 'INT':: The maximum read length permitted by the BAQ algorithm [500]. Variants are still called on longer reads, but they will not be passed through the BAQ method. This limit exists to prevent excessively long BAQ times and high memory usage. Note if partial BAQ is enabled with '-D' then raising this parameter will likely not have a significant a CPU cost. *-o, --open-prob* 'INT':: Phred-scaled gap open sequencing error probability. Reducing 'INT' leads to more indel calls. (The same short option is used for both *--open-prob* and *--output*. When -o's argument contains only an optional + or - sign followed by the digits 0 to 9, it is interpreted as *--open-prob*.) [40] *-p, --per-sample-mF*:: Apply *-m* and *-F* thresholds per sample to increase sensitivity of calling. By default both options are applied to reads pooled from all samples. *-P, --platforms* 'STR':: Comma-delimited list of platforms (determined by *@RG-PL*) from which indel candidates are obtained. It is recommended to collect indel candidates from sequencing technologies that have low indel error rate such as ILLUMINA [all] ==== Examples: Call SNPs and short INDELs, then mark low quality sites and sites with the read depth exceeding a limit. (The read depth should be adjusted to about twice the average read depth as higher read depths usually indicate problematic regions which are often enriched for artefacts.) One may consider to add *-C50* to mpileup if mapping quality is overestimated for reads containing excessive mismatches. Applying this option usually helps for BWA-backtrack alignments, but may not other aligners. ---- bcftools mpileup -Ou -f ref.fa aln.bam | \ bcftools call -Ou -mv | \ bcftools filter -s LowQual -e '%QUAL<20 || DP>100' > var.flt.vcf ---- [[norm]] === bcftools norm ['OPTIONS'] 'file.vcf.gz' Left-align and normalize indels, check if REF alleles match the reference, split multiallelic sites into multiple rows; recover multiallelics from multiple rows. Left-alignment and normalization will only be applied if the *<>* option is supplied. *-a, --atomize*:: Decompose complex variants, e.g. split MNVs into consecutive SNVs. See also *--atom-overlaps* and *--old-rec-tag*. *--atom-overlaps* '.'|'*':: Alleles missing because of an overlapping variant can be set either to missing (.) or to the star alele (*), as recommended by the VCF specification. IMPORTANT: Note that asterisk is expaneded by shell and must be put in quotes or escaped by a backslash: ---- # Before atomization: 100 CC C,GG 1/2 # After: # bcftools norm -a --atom-overlaps . 100 C G ./1 100 CC C 1/. 101 C G ./1 # After: # bcftools norm -a --atom-overlaps '*' # bcftools norm -a --atom-overlaps \* 100 C G,* 2/1 100 CC C,* 1/2 101 C G,* 2/1 ---- *-c, --check-ref* 'e'|'w'|'x'|'s':: what to do when incorrect or missing REF allele is encountered: exit ('e'), warn ('w'), exclude ('x'), or set/fix ('s') bad sites. The 'w' option can be combined with 'x' and 's'. Note that 's' can swap alleles and will update genotypes (GT) and AC counts, but will not attempt to fix PL or other fields. Also note, and this cannot be stressed enough, that 's' will NOT fix strand issues in your VCF, do NOT use it for that purpose!!! (Instead see and .) *-d, --rm-dup* 'snps'|'indels'|'both'|'all'|'exact':: If a record is present multiple times, output only the first instance. See also *--collapse* in *<>*. *-D, --remove-duplicates*:: If a record is present in multiple files, output only the first instance. Alias for *-d none*, deprecated. *-e, --exclude* 'EXPRESSION':: do not normalize input records for which 'EXPRESSION' is true. For valid expressions see *<>*. Note that duplicate removal ignores this option. *-f, --fasta-ref* 'FILE'[[fasta_ref]]:: reference sequence. Supplying this option will turn on left-alignment and normalization, however, see also the *<>* option below. *--force*:: try to proceed with *-m-* even if malformed tags with incorrect number of fields are encountered, discarding such tags. (Experimental, use at your own risk.) *-g, --gff-annot* 'FILE':: when a GFF file is provided, follow HGVS 3'rule and right-align variants in transcripts on the forward strand. In case of overlapping transcripts, the default mode is to left-align the variant. For a description of the supported GFF3 file format see *<>*. *-i, --include* 'EXPRESSION':: normalize only input records for which 'EXPRESSION' is true. For valid expressions see *<>*. Note that duplicate removal ignores this option. *--keep-sum* 'TAG'[,...]:: keep vector sum constant when splitting multiallelic sites. Only AD tag is currently supported. See also https://github.com/samtools/bcftools/issues/360 *-m, --multiallelics* *-*|*+*['snps'|'indels'|'both'|'any']:: split multiallelic sites into biallelic records (*-*) or join biallelic sites into multiallelic records (*+*). An optional type string can follow which controls variant types which should be split or merged together: If only SNP records should be split or merged, specify 'snps'; if both SNPs and indels should be merged separately into two records, specify 'both'; if SNPs and indels should be merged into a single record, specify 'any'. {nbsp} + {nbsp} + Note that multiallelic sites with both SNPs and indels will be split into biallelic sites with both *-m -snps* and *-m -indels*. *--multi-overlaps* '0'|'.':: use the reference ('0') or missing ('.') allele for overlapping alleles after splitting multiallelic sites *--no-version*:: see *<>* *-N, --do-not-normalize*[[do_not_normalize]]:: the '-c s' option can be used to fix or set the REF allele from the reference '-f'. The '-N' option will not turn on indel normalisation as the '-f' option normally implies *--old-rec-tag* 'STR':: Add INFO/STR annotation with the original record. The format of the annotation is CHROM|POS|REF|ALT|USED_ALT_IDX. *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --strict-filter*:: when merging ('-m+'), merged site is PASS only if all sites being merged PASS *-S, --sort* 'pos'|'lex':: when splitting sites or processing duplicates, sort records on output by POS only ('pos', the default) or by POS and lexicographically by REF+ALT ('lex') *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *--threads* 'INT':: see *<>* *-v, --verbose* 'INT':: verbosity level of GFF parsing (0-2) *-w, --site-win* 'INT':: maximum distance between two records to consider when locally sorting variants which changed position during the realignment *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. [[plugin]] === bcftools [plugin 'NAME'|+'NAME'] '[OPTIONS]' 'FILE' -- '[PLUGIN OPTIONS]' A common framework for various utilities. The plugins can be used the same way as normal commands only their name is prefixed with "+". Most plugins accept two types of parameters: general options shared by all plugins followed by a separator, and a list of plugin-specific options. There are some exceptions to this rule, some plugins do not accept the common options and implement their own parameters. Therefore please pay attention to the usage examples that each plugin comes with. ==== VCF input options: *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* ==== VCF output options: *--no-version*:: see *<>* *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *--threads* 'INT':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. ==== Plugin options: *-h, --help*:: list plugin's options *-l, --list-plugins*:: List all available plugins. + By default, appropriate system directories are searched for installed plugins. You can override this by setting the BCFTOOLS_PLUGINS environment variable to a colon-separated list of directories to search. If BCFTOOLS_PLUGINS begins with a colon, ends with a colon, or contains adjacent colons, the system directories are also searched at that position in the list of directories. *-v, --verbose*:: print debugging information to debug plugin failure *-V, --version*:: print version string and exit ==== List of plugins coming with the distribution: *ad-bias*:: find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD) *add-variantkey*:: add VariantKey INFO fields VKX and RSX *af-dist*:: collect AF deviation stats and GT probability distribution given AF and assuming HWE *allele-length*:: count the frequency of the length of REF, ALT and REF+ALT *check-ploidy*:: check if ploidy of samples is consistent for all sites *check-sparsity*:: print samples without genotypes in a region or chromosome *color-chrs*:: color shared chromosomal segments, requires trio VCF with phased GTs *contrast*:: runs a basic association test, per-site or in a region, and checks for novel alleles and genotypes in two groups of samples. Adds the following INFO annotations: - PASSOC .. Fisher's exact test probability of genotypic association (REF vs non-REF allele) - FASSOC .. proportion of non-REF allele in controls and cases - NASSOC .. number of control-ref, control-alt, case-ref and case-alt alleles - NOVELAL .. lists samples with a novel allele not observed in the control group - NOVELGT .. lists samples with a novel genotype not observed in the control group *counts*:: a minimal plugin which counts number of SNPs, Indels, and total number of sites. *dosage*:: print genotype dosage. By default the plugin searches for PL, GL and GT, in that order. *fill-from-fasta*:: fill INFO or REF field based on values in a fasta file *fill-tags*:: set various INFO tags. The list of tags supported in this version: - INFO/AC Number:A Type:Integer .. Allele count in genotypes - INFO/AC_Hom Number:A Type:Integer .. Allele counts in homozygous genotypes - INFO/AC_Het Number:A Type:Integer .. Allele counts in heterozygous genotypes - INFO/AC_Hemi Number:A Type:Integer .. Allele counts in hemizygous genotypes - INFO/AF Number:A Type:Float .. Allele frequency - INFO/AN Number:1 Type:Integer .. Total number of alleles in called genotypes - INFO/ExcHet Number:A Type:Float .. Test excess heterozygosity; 1=good, 0=bad - INFO/END Number:1 Type:Integer .. End position of the variant - INFO/F_MISSING Number:1 Type:Float .. Fraction of missing genotypes - INFO/HWE Number:A Type:Float .. HWE test (PMID:15789306); 1=good, 0=bad - INFO/MAF Number:A Type:Float .. Minor Allele frequency - INFO/NS Number:1 Type:Integer .. Number of samples with data - INFO/TYPE Number:. Type:String .. The record type (REF,SNP,MNP,INDEL,etc) - FORMAT/VAF Number:A Type:Float .. The fraction of reads with the alternate allele, requires FORMAT/AD or ADF+ADR - FORMAT/VAF1 Number:1 Type:Float .. The same as FORMAT/VAF but for all alternate alleles cumulatively - TAG=func(TAG) Number:1 Type:Integer .. Experimental support for user-defined expressions such as "DP=sum(DP)" *fixploidy*:: sets correct ploidy *fixref*:: determine and fix strand orientation *frameshifts*:: annotate frameshift indels *GTisec*:: count genotype intersections across all possible sample subsets in a vcf file *GTsubset*:: output only sites where the requested samples all exclusively share a genotype *guess-ploidy*:: determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT) in the non-PAR region of chrX. *gvcfz*:: compress gVCF file by resizing non-variant blocks according to specified criteria *impute-info*:: add imputation information metrics to the INFO field based on selected FORMAT tags *indel-stats*:: calculates per-sample or de novo indels stats. The usage and format is similar to *smpl-stats* and *trio-stats* *isecGT*:: compare two files and set non-identical genotypes to missing *mendelian*:: count Mendelian consistent / inconsistent genotypes (deprecated, use +mendelian2 instead) *mendelian2*:: count Mendelian consistent / inconsistent genotypes. *missing2ref*:: sets missing genotypes ("./.") to ref allele ("0/0" or "0|0") *parental-origin*:: determine parental origin of a CNV region *prune*:: prune sites by missingness, allele frequency or linkage disequilibrium. Alternatively, annotate sites with r2, Lewontin's D' (PMID:19433632), Ragsdale's D (PMID:31697386). *remove-overlaps*:: remove overlapping variants and duplicate sites *scatter*:: intended as an inverse to `bcftools concat`, scatter VCF by chunks or regions, creating multiple VCFs. *setGT*:: general tool to set genotypes according to rules requested by the user *smpl-stats*:: calculates basic per-sample stats. The usage and format is similar to *indel-stats* and *trio-stats*. *split*:: split VCF by sample, creating single- or multi-sample VCFs *split-vep*:: extract fields from structured annotations such as INFO/CSQ created by VEP or INFO/BCSQ created by bcftools/csq. These can be added as a new INFO field to the VCF or in a custom text format. See for more. *tag2tag*:: Convert between similar tags, such as GL,PL,GP or QR,QA,QS or tags with localized alleles e.g. LPL,LAD. See for more. *trio-dnm2*:: screen variants for possible de-novo mutations in trios *trio-stats*:: calculate transmission rate in trio children. The usage and format is similar to *indel-stats* and *smpl-stats*. *trio-switch-rate*:: calculate phase switch rate in trio samples, children samples must have phased GTs *variant-distance*:: annotate sites with the distance to the nearest variant *variantkey-hex*:: generate unsorted VariantKey-RSid index files in hexadecimal format ==== Examples: ---- # List options common to all plugins bcftools plugin # List available plugins bcftools plugin -l # Run a plugin bcftools plugin counts in.vcf # Run a plugin using the abbreviated "+" notation bcftools +counts in.vcf # Run a plugin from an explicit location bcftools +/path/to/counts.so in.vcf # The input VCF can be streamed just like in other commands cat in.vcf | bcftools +counts # Print usage information of plugin "dosage" bcftools +dosage -h # Replace missing genotypes with 0/0 bcftools +missing2ref in.vcf # Replace missing genotypes with 0|0 bcftools +missing2ref in.vcf -- -p ---- ==== Plugins troubleshooting: Things to check if your plugin does not show up in the *bcftools plugin -l* output: - Run with the *-v* option for verbose output: *bcftools plugin -lv* - Does the environment variable BCFTOOLS_PLUGINS include the correct path? ==== Plugins API: ---- // Short description used by 'bcftools plugin -l' const char *about(void); // Longer description used by 'bcftools +name -h' const char *usage(void); // Called once at startup, allows initialization of local variables. // Return 1 to suppress normal VCF/BCF header output, -1 on critical // errors, 0 otherwise. int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr); // Called for each VCF record, return NULL to suppress the output bcf1_t *process(bcf1_t *rec); // Called after all lines have been processed to clean up void destroy(void); ---- [[polysomy]] === bcftools polysomy ['OPTIONS'] 'file.vcf.gz' Detect number of chromosomal copies in VCFs annotates with the Illumina's B-allele frequency (BAF) values. Note that this command is not compiled in by default, see the section *Optional Compilation with GSL* in the INSTALL file for help. ==== General options: *-o, --output-dir* 'path':: output directory *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --sample* 'string':: sample name *-t, --targets* 'LIST':: see *<>* *-T, --targets-file* 'FILE':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-v, --verbose*:: verbose debugging output which gives hints about the thresholds and decisions made by the program. Note that the exact output can change between versions. ==== Algorithm options: *-b, --peak-size* 'float':: the minimum peak size considered as a good match can be from the interval [0,1] where larger is stricter *-c, --cn-penalty* 'float':: a penalty for increasing copy number state. How this works: multiple peaks are always a better fit than a single peak, therefore the program prefers a single peak (normal copy number) unless the absolute deviation of the multiple peaks fit is significantly smaller. Here the meaning of "significant" is given by the 'float' from the interval [0,1] where larger is stricter. *-f, --fit-th* 'float':: threshold for goodness of fit (normalized absolute deviation), smaller is stricter *-i, --include-aa*:: include also the AA peak in CN2 and CN3 evaluation. This usually requires increasing *-f*. *-m, --min-fraction* 'float':: minimum distinguishable fraction of aberrant cells. The experience shows that trustworthy are estimates of 20% and more. *-p, --peak-symmetry* 'float':: a heuristics to filter failed fits where the expected peak symmetry is violated. The 'float' is from the interval [0,1] and larger is stricter [[query]] === bcftools query ['OPTIONS'] 'file.vcf.gz' ['file.vcf.gz' [...]] Extracts fields from VCF or BCF files and outputs them in user-defined format. *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *--force-samples*:: continue even when some samples requested via *-s/-S* do not exist *-f, --format* 'FORMAT':: learn by example, see below *-F, --print-filtered* 'STR':: by default, samples failing *-i/-e* filtering expressions are suppressed from output when FORMAT fields are queried (for example '%CHROM %POS [ %GT]'). With *-F*, such fields will be still printed but instead of their actual value, 'STR' will be used. *-H, --print-header*:: print header. By default, the header is printed with column indices, e.g. "#[1]CHROM". These can be suppressed by giving the option twice, "`-HH`". *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-l, --list-samples*:: list sample names and exit *-N, --disable-automatic-newline*:: disable automatic addition of a missing newline character at the end of the formatting expression. By default, the program checks if the expression contains a newline and appends it if not, to prevent formatting the entire output into a single line by mistake. Note that versions prior to 1.18 had no automatic check and newline had to be included explicitly. *-o, --output* 'FILE':: see *<>* *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* 'LIST':: see *<>* *-S, --samples-file* 'FILE':: see *<>* *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-u, --allow-undef-tags*:: do not throw an error if there are undefined tags in the format string, print "." instead *-v, --vcf-list* 'FILE':: process multiple VCFs listed in the file ==== Format: %CHROM The CHROM column (similarly also other columns: POS, ID, REF, ALT, QUAL, FILTER) %END End position of the REF allele %END0 End position of the REF allele in 0-based coordinates %FIRST_ALT Alias for %ALT{0} %FORMAT Prints all FORMAT fields or a subset of samples with -s or -S %GT Genotype (e.g. 0/1) %INFO Prints the whole INFO column %INFO/TAG Any tag in the INFO column %IUPACGT Genotype translated to IUPAC ambiguity codes (e.g. M instead of C/A) %LINE Prints the whole line %MASK Indicates presence of the site in other files (with multiple files) %N_PASS(expr) Number of samples that pass the filtering expression (see *<>*) %POS0 POS in 0-based coordinates %PBINOM(TAG) Calculate phred-scaled binomial probability, the allele index is determined from GT %SAMPLE Sample name %TAG{INT} Curly brackets to print a subfield (e.g. INFO/TAG{1}, the indexes are 0-based) %TBCSQ Translated FORMAT/BCSQ. See the csq command above for explanation and examples. %TGT Translated genotype (e.g. C/A) %TYPE Variant type (REF, SNP, MNP, INDEL, BND, OTHER) %VKX VariantKey, biallelic hexadecimal encoding of CHROM,POS,REF,ALT (https://github.com/tecnickcom/variantkey) [] Format fields must be enclosed in brackets to loop over all samples \n new line \t tab character Everything else is printed verbatim. ==== Examples: # Print chromosome, position, ref allele and the first alternate allele bcftools query -f '%CHROM %POS %REF %ALT{0}\n' file.vcf.gz # Similar to above, but use tabs instead of spaces, add sample name and genotype bcftools query -f '%CHROM\t%POS\t%REF\t%ALT[\t%SAMPLE=%GT]\n' file.vcf.gz # Print FORMAT/GT fields followed by FORMAT/GT fields bcftools query -f 'GQ:[ %GQ] \t GT:[ %GT]\n' file.vcf # Make a BED file: chr, pos (0-based), end pos (1-based), id bcftools query -f'%CHROM\t%POS0\t%END\t%ID\n' file.bcf # Print only samples with alternate (non-reference) genotypes bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' -i'GT="alt"' file.bcf # Print all samples at sites with at least one alternate genotype bcftools view -i'GT="alt"' file.bcf -Ou | bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' # Print phred-scaled binomial probability from FORMAT/AD tag for all heterozygous genotypes bcftools query -i'GT="het"' -f'[%CHROM:%POS %SAMPLE %GT %PBINOM(AD)\n]' file.vcf # Print the second value of AC field if bigger than 10. Note the (unfortunate) difference in # index subscript notation: formatting expressions (-f) uses "{}" while filtering expressions # (-i) use "[]". This is for historic reasons and backward-compatibility. bcftools query -f '%AC{1}\n' -i 'AC[1]>10' file.vcf.gz # Print all samples at sites where at least one sample has DP=1 or DP=2. In the second case # print only samples with DP=1 or DP=2, the difference is in the logical operator used, || vs |. bcftools query -f '[%SAMPLE %GT %DP\n]' -i 'FMT/DP=1 || FMT/DP=2' file.vcf bcftools query -f '[%SAMPLE %GT %DP\n]' -i 'FMT/DP=1 | FMT/DP=2' file.vcf [[reheader]] === bcftools reheader ['OPTIONS'] 'file.vcf.gz' Modify header of VCF/BCF files, change sample names. *-f, --fai* 'FILE':: add to the header contig names and their lengths from the provided fasta index file (.fai). Lengths of existing contig lines will be updated and contig lines not present in the fai file will be removed *-h, --header* 'FILE':: new VCF header *-o, --output* 'FILE':: see *<>* *-s, --samples* 'FILE':: new sample names, one name per line, in the same order as they appear in the VCF file. Alternatively, only samples which need to be renamed can be listed as "old_name new_name\n" pairs separated by whitespaces, each on a separate line. If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\ a\ good\ sample\ name". *-T, --temp-prefix* 'PATH':: this option is ignored, but left for compatibility with earlier versions of bcftools. *--threads* 'INT':: see *<>* [[roh]] === bcftools roh ['OPTIONS'] 'file.vcf.gz' A program for detecting runs of homo/autozygosity. Only bi-allelic sites are considered. ==== The HMM model: -------------------------------------- Notation: D = Data, AZ = autozygosity, HW = Hardy-Weinberg (non-autozygosity), f = non-ref allele frequency Emission probabilities: oAZ = P_i(D|AZ) = (1-f)*P(D|RR) + f*P(D|AA) oHW = P_i(D|HW) = (1-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1-f)*P(D|RA) Transition probabilities: tAZ = P(AZ|HW) .. from HW to AZ, the -a parameter tHW = P(HW|AZ) .. from AZ to HW, the -H parameter ci = P_i(C) .. probability of cross-over at site i, from genetic map AZi = P_i(AZ) .. probability of site i being AZ/non-AZ, scaled so that AZi+HWi = 1 HWi = P_i(HW) P_{i+1}(AZ) = oAZ * max[(1 - tAZ * ci) * AZ{i-1} , tAZ * ci * (1-AZ{i-1})] P_{i+1}(HW) = oHW * max[(1 - tHW * ci) * (1-AZ{i-1}) , tHW * ci * AZ{i-1}] -------------------------------------- ==== General Options: *--AF-dflt* 'FLOAT':: in case allele frequency is not known, use the 'FLOAT'. By default, sites where allele frequency cannot be determined, or is 0, are skipped. *--AF-tag* 'TAG':: use the specified INFO tag 'TAG' as an allele frequency estimate instead of the default AC and AN tags. Sites which do not have 'TAG' will be skipped. *--AF-file* 'FILE':: Read allele frequencies from a tab-delimited file containing the columns: CHROM\tPOS\tREF,ALT\tAF. The file can be compressed with *bgzip* and indexed with tabix -s1 -b2 -e2. Sites which are not present in the 'FILE' or have different reference or alternate allele will be skipped. Note that such a file can be easily created from a VCF using: ---- bcftools query -f'%CHROM\t%POS\t%REF,%ALT\t%INFO/TAG\n' file.vcf | bgzip -c > freqs.tab.gz ---- *-b, --buffer-size* 'INT'[,'INT']:: when the entire many-sample file cannot fit into memory, a sliding buffer approach can be used. The first value is the number of sites to keep in memory. If negative, it is interpreted as the maximum memory to use, in MB. The second, optional, value sets the number of overlapping sites. The default overlap is set to roughly 1% of the buffer size. *-e, --estimate-AF* ['TAG',]'FILE':: estimate the allele frequency by recalculating INFO/AC and INFO/AN on the fly, using the specified 'TAG' which can be either FORMAT/GT ("GT") or FORMAT/PL ("PL"). If 'TAG' is not given, "GT" is assumed. Either all samples ("-") or samples listed in 'FILE' will be included. For example, use "PL,-" to estimate AF from FORMAT/PL of all samples. If neither *-e* nor the other *--AF-...* options are given, the allele frequency is estimated from AC and AN counts which are already present in the INFO field. *--exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-G, --GTs-only* 'FLOAT':: use genotypes (FORMAT/GT fields) ignoring genotype likelihoods (FORMAT/PL), setting PL of unseen genotypes to 'FLOAT'. Safe value to use is 30 to account for GT errors. *--include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-I, --skip-indels*:: skip indels as their genotypes are usually enriched for errors *-m, --genetic-map* 'FILE':: genetic map in the format required also by IMPUTE2. Only the first and third column are used (position and Genetic_Map(cM)). The 'FILE' can be a single file or a file mask, where string "{CHROM}" is replaced with chromosome name. *-M, --rec-rate* 'FLOAT':: constant recombination rate per bp. In combination with *--genetic-map*, the *--rec-rate* parameter is interpreted differently, as 'FLOAT'-fold increase of transition probabilities, which allows the model to become more sensitive yet still account for recombination hotspots. Note that also the range of the values is therefore different in both cases: normally the parameter will be in the range (1e-3,1e-9) but with *--genetic-map* it will be in the range (10,1000). *-o, --output* 'FILE':: Write output to the 'FILE', by default the output is printed on stdout *-O, --output-type* 's'|'r'['z']:: Generate per-site output ('s') or per-region output ('r'). By default both types are printed and the output is uncompressed. Add 'z' for a compressed output. ---- # Output fields: RG = predicted homo/autozygous regions - Sample - Chromosome - Start - End - Length (bp) - Number of markers - Quality .. average phred score in the region from the forward-backward algorithm ST = per-site output showing: - Sample - Chromosome - Position - State .. predicted state from the Viterbi algorithm, 0 for normal (HW, Hardy-Weinberg) or 1 for autozygous (AZ) - Quality .. quality score from the forward-backward algorithm ---- *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* 'LIST':: see *<>* *-S, --samples-file* 'FILE':: see *<>* *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* ==== HMM Options: *-a, --hw-to-az* 'FLOAT':: P(AZ|HW) transition probability from AZ (autozygous) to HW (Hardy-Weinberg) state *-H, --az-to-hw* 'FLOAT':: P(HW|AZ) transition probability from HW to AZ state *-V, --viterbi-training* 'FLOAT':: estimate HMM parameters using Baum-Welch algorithm, using the convergence threshold 'FLOAT', e.g. 1e-10 (experimental) [[sort]] === bcftools sort ['OPTIONS'] file.bcf *-m, --max-mem* 'FLOAT'['kMG']:: Maximum memory to use. Approximate, affects the number of temporary files written to the disk. Note that if the command fails at this step because of too many open files, your system limit on the number of open files ("ulimit") may need to be increased. *-o, --output* 'FILE':: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-T, --temp-dir* 'DIR':: Use this directory to store temporary files. If the last six characters of the string DIR are XXXXXX, then these are replaced with a string that makes the directory name unique. *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. [[stats]] === bcftools stats ['OPTIONS'] 'A.vcf.gz' ['B.vcf.gz'] Parses VCF or BCF and produces text file stats which is suitable for machine processing and can be plotted using *<>*. When two files are given, the program generates separate stats for intersection and the complements. By default only sites are compared, *-s*/*-S* must given to include also sample columns. When one VCF file is specified on the command line, then stats by non-reference allele frequency, depth distribution, stats by quality and per-sample counts, singleton stats, etc. are printed. When two VCF files are given, then stats such as concordance (Genotype concordance by non-reference allele frequency, Genotype concordance by sample, Non-Reference Discordance) and correlation are also printed. Per-site discordance (PSD) is also printed in *--verbose* mode. *--af-bins* 'LIST'|'FILE':: comma separated list of allele frequency bins (e.g. 0.1,0.5,1) or a file listing the allele frequency bins one per line (e.g. 0.1\n0.5\n1) *--af-tag* 'TAG':: allele frequency INFO tag to use for binning. By default the allele frequency is estimated from AC/AN, if available, or directly from the genotypes (GT) if not. *-1, --1st-allele-only*:: consider only the 1st alternate allele at multiallelic sites *-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none':: see *<>* *-d, --depth* 'INT','INT','INT':: ranges of depth distribution: min, max, and size of the bin *--debug*:: produce verbose per-site and per-sample output *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-E, --exons* 'file.gz':: tab-delimited file with exons for indel frameshifts statistics. The columns of the file are CHR, FROM, TO, with 1-based, inclusive, positions. The file is BGZF-compressed and indexed with tabix ---- tabix -s1 -b2 -e3 file.gz ---- *-f, --apply-filters* 'LIST':: see *<>* *-F, --fasta-ref* 'ref.fa':: faidx indexed reference sequence file to determine INDEL context *-i, --include* 'EXPRESSION':: include only sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-I, --split-by-ID*:: collect stats separately for sites which have the ID column set ("known sites") or which do not have the ID column set ("novel sites"). *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-s, --samples* 'LIST':: see *<>* *-S, --samples-file* 'FILE':: see *<>* *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *-u, --user-tstv* '':: collect Ts/Tv stats for any tag using the given binning [0:1:100] *-v, --verbose*:: produce verbose per-site and per-sample output [[view]] === bcftools view ['OPTIONS'] 'file.vcf.gz' ['REGION' [...]] View, subset and filter VCF or BCF files by position and filtering expression. Convert between VCF and BCF. Former *bcftools subset*. ==== Output options *-G, --drop-genotypes*:: drop individual genotype information (after subsetting if *-s* option is set) *-h, --header-only*:: output the VCF header only (see also *<>*) *-H, --no-header*:: suppress the header in VCF output *--with-header*:: output both VCF header and records (this is the default, but the option is useful for explicitness or to reset the effects of *-h* or *-H*) *-l, --compression-level* ['0-9']:: compression level. 0 stands for uncompressed, 1 for best speed and 9 for best compression. *--no-version*:: see *<>* *-O, --output-type* 'b'|'u'|'z'|'v'[0-9]:: see *<>* *-o, --output* 'FILE': output file name. If not present, the default is to print to standard output (stdout). *-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-R, --regions-file* 'file':: see *<>* *--regions-overlap* '0'|'1'|'2':: see *<>* *-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: see *<>* *-T, --targets-file* 'file':: see *<>* *--targets-overlap* '0'|'1'|'2':: see *<>* *--threads* 'INT':: see *<>* *-W*['FMT']*, -W*[='FMT']*, --write-index*[='FMT']:: Automatically index the output file. 'FMT' is optional and can be one of "tbi" or "csi" depending on output file format. ==== Subset options: *-A, --trim-unseen-alleles*:: remove the unseen allele '<*>' or '' at variant sites when the option is given once (-A) or at all sites when the options is given twice ('-AA'). *-a, --trim-alt-alleles*:: remove alleles not seen in the genotype fields from the ALT column. Note that if no alternate allele remains after trimming, the record itself is not removed but ALT is set to ".". If the option *-s* or *-S* is given, removes alleles not seen in the subset. INFO and FORMAT tags declared as Type=A, G or R will be trimmed as well. *--force-samples*:: only warn about unknown subset samples *-I, --no-update*:: do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN) *-s, --samples* 'LIST':: see *<>*. Note that it is possible to create multiple subsets simultaneously using the *split* plugin. *-S, --samples-file* 'FILE':: see *<>*. Note that it is possible to create multiple subsets simultaneously using the *split* plugin. ==== Filter options: Note that filter options below dealing with counting the number of alleles will, for speed, first check for the values of AC and AN in the INFO column to avoid parsing all the genotype (FORMAT/GT) fields in the VCF. This means that filters like '--uncalled', --exclude-uncalled', or '--min-af 0.1' will be calculated from INFO/AC and INFO/AN when available or FORMAT/GT otherwise. However, it will not attempt to use any other existing field, like INFO/AF for example. For that, use '--exclude AF<0.1' instead. Also note that one must be careful when sample subsetting and filtering is performed in a single command because the order of internal operations can influence the result. For example, the *-i/-e* filtering is performed before sample removal, but the *-P* filtering is performed after, and some are inherently ambiguous, for example allele counts can be taken from the INFO column when present but calculated on the fly when absent. Therefore it is strongly recommended to spell out the required order explicitly by separating such commands into two steps. (Make sure to use the *-O u* option when piping!) *-c, --min-ac* 'INT'[':nref'|':alt1'|':minor'|':major'|:'nonmajor']:: minimum allele count (INFO/AC) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference ('nref', the default), 1st alternate ('alt1'), the least frequent ('minor'), the most frequent ('major') or sum of all but the most frequent ('nonmajor') alleles. *-C, --max-ac* 'INT'[':nref'|':alt1'|':minor'|:'major'|:'nonmajor']:: maximum allele count (INFO/AC) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference ('nref', the default), 1st alternate ('alt1'), the least frequent ('minor'), the most frequent ('major') or sum of all but the most frequent ('nonmajor') alleles. *-e, --exclude* 'EXPRESSION':: exclude sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-f, --apply-filters* 'LIST':: see *<>* *-g, --genotype* [^]['hom'|'het'|'miss']:: include only sites with one or more homozygous ('hom'), heterozygous ('het') or missing ('miss') genotypes. When prefixed with '^', the logic is reversed; thus '^het' excludes sites with heterozygous genotypes. *-i, --include* 'EXPRESSION':: include sites for which 'EXPRESSION' is true. For valid expressions see *<>*. *-k, --known*:: print known sites only (ID column is not ".") *-m, --min-alleles* 'INT':: print sites with at least 'INT' alleles listed in REF and ALT columns *-M, --max-alleles* 'INT':: print sites with at most 'INT' alleles listed in REF and ALT columns. Use *-m2 -M2 -v snps* to only view biallelic SNPs. *-n, --novel*:: print novel sites only (ID column is ".") *-p, --phased*:: print sites where all samples are phased. Haploid genotypes are considered phased. Missing genotypes considered unphased unless the phased bit is set. *-P, --exclude-phased*:: exclude sites where all samples are phased *-q, --min-af* 'FLOAT'[':nref'|':alt1'|':minor'|':major'|':nonmajor']:: minimum allele frequency (INFO/AC / INFO/AN) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference ('nref', the default), 1st alternate ('alt1'), the least frequent ('minor'), the most frequent ('major') or sum of all but the most frequent ('nonmajor') alleles. *-Q, --max-af* 'FLOAT'[':nref'|':alt1'|':minor'|':major'|':nonmajor']:: maximum allele frequency (INFO/AC / INFO/AN) of sites to be printed. Specifying the type of allele is optional and can be set to non-reference ('nref', the default), 1st alternate ('alt1'), the least frequent ('minor'), the most frequent ('major') or sum of all but the most frequent ('nonmajor') alleles. *-u, --uncalled*:: print sites without a called genotype, i.e. print sites with all genotypes missing. Note that the missingness is determined from INFO/AN and AC tags when available to avoid parsing sample fields. *-U, --exclude-uncalled*:: exclude sites without a called genotype, i.e. print sites with at least one non-missing genotype. Note that the missingness is determined from INFO/AN and AC tags when available to avoid parsing sample fields. *-v, --types* 'snps'|'indels'|'mnps'|'other':: comma-separated list of variant types to select. Site is selected if any of the ALT alleles is of the type requested. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT. Use *--include* to select based on INFO tags. *-V, --exclude-types* 'snps'|'indels'|'mnps'|'ref'|'bnd'|'other':: comma-separated list of variant types to exclude. Site is excluded if any of the ALT alleles is of the type requested. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT. Use *--exclude* to exclude based on INFO tags. *-x, --private*:: print sites where only the subset samples carry an non-reference allele. Requires *--samples* or *--samples-file*. *-X, --exclude-private*:: exclude sites where only the subset samples carry an non-reference allele [[help]] === bcftools help ['COMMAND'] | bcftools --help ['COMMAND'] Display a brief usage message listing the bcftools commands available. If the name of a command is also given, e.g., bcftools help view, the detailed usage message for that particular command is displayed. [[version]] === bcftools ['--version'|'-v'] Display the version numbers and copyright information for bcftools and the important libraries used by bcftools. [[version-only]] === bcftools ['--version-only'] Display the full bcftools version number in a machine-readable format. SCRIPTS ------- [[gff2gff]] === gff2gff Attempts to fix a GFF file to be correctly parsed by *<>*. -- zcat in.gff.gz | gff2gff | gzip -c > out.gff.gz -- [[plot-vcfstats]] === plot-vcfstats ['OPTIONS'] 'file.vchk' [...] Script for processing output of *<>*. It can merge results from multiple outputs (useful when running the stats for each chromosome separately), plots graphs and creates a PDF presentation. *-m, --merge*:: Merge vcfstats files to STDOUT, skip plotting. *-p, --prefix* 'DIR':: The output directory. This directory will be created if it does not exist. *-P, --no-PDF*:: Skip the PDF creation step. *-r, --rasterize*:: Rasterize PDF images for faster rendering. This is the default and the opposite of *-v, --vectors*. *-s, --sample-names*:: Use sample names for xticks rather than numeric IDs. *-t, --title* 'STRING':: Identify files by these titles in plots. The option can be given multiple times, for each ID in the *<>* output. If not present, the script will use abbreviated source file names for the titles. *-v, --vectors*:: Generate vector graphics for PDF images, the opposite of *-r, --rasterize*. *-T, --main-title* 'STRING':: Main title for the PDF. *Example:* -- # Generate the stats bcftools stats -s - > file.vchk # Plot the stats plot-vcfstats -p outdir file.vchk # The final looks can be customized by editing the generated # 'outdir/plot.py' script and re-running manually cd outdir && python plot.py && pdflatex summary.tex -- [[expressions]] FILTERING EXPRESSIONS --------------------- These filtering expressions are accepted by most of the commands. .Valid expressions may contain: * numerical constants, string constants, file names (indicated by the prefix '@') 1, 1.0, 1e-4 "String" @file_name * arithmetic operators (addition, multiplication, subtraction, division, modulo) +, *, -, /, % * comparison operators == (same as =), >, >=, <=, <, != * regex operators "\~" and its negation "!~". The expressions are case sensitive unless "/i" is added. INFO/HAYSTACK ~ "needle" INFO/HAYSTACK ~ "NEEDless/i" * parentheses (, ) * logical operators. See also the examples below and the http://samtools.github.io/bcftools/howtos/filtering.html[filtering tutorial] about the distinction between "&&" vs "&" and "||" vs "|". &&, &, ||, | * INFO tags, FORMAT tags, column names INFO/DP or DP FORMAT/DV, FMT/DV, or DV FILTER, QUAL, ID, CHROM, POS, REF, ALT[0] * the FILTER column can be queried as follows: FILTER="PASS" FILTER="." FILTER="A" .. exact match, for example "A;B" does not pass FILTER="A;B" .. exact match, "A;B" and "B;A" pass, everything else fails FILTER!="A" .. exact match, for example "A;B" does pass FILTER~"A" .. subset match, for example both "A" and "A;B" pass FILTER~"A;B" .. subset match, pass only if both "A" and "B" are present FILTER!~"A" .. complement match, for example both "A" and "A;B" fail FILTER!~"A;B" .. complement match, fail if both "A" and "B" are present * 1 (or 0) to test the presence (or absence) of a flag FlagA=1 && FlagB=0 * "." to test missing values DP=".", DP!=".", ALT="." * missing genotypes can be matched regardless of phase and ploidy (".|.", "./.", ".", "0|.") using these expressions GT="mis", GT~"\.", GT!~"\." * missing genotypes can be matched including the phase and ploidy (".|.", "./.", ".") using these expressions GT=".|.", GT="./.", GT="." * sample genotype: reference (haploid or diploid), alternate (hom or het, haploid or diploid), missing genotype, homozygous, heterozygous, haploid, ref-ref hom, alt-alt hom, ref-alt het, alt-alt het, haploid ref, haploid alt (case-insensitive) GT="ref" GT="alt" GT="mis" GT="hom" GT="het" GT="hap" GT="RR" GT="AA" GT="RA" or GT="AR" GT="Aa" or GT="aA" GT="R" GT="A" * TYPE for variant type in REF,ALT columns (indel,snp,mnp,ref,bnd,other,overlap, see *<>*). Use the regex operator "\~" to require at least one allele of the given type or the equal sign "=" to require that all alleles are of the given type. Compare TYPE="snp" TYPE~"snp" TYPE!="snp" TYPE!~"snp" * array subscripts (0-based), "*" for any element, "-" to indicate a range. Note that for querying FORMAT vectors, the colon ":" can be used to select a sample and an element of the vector, as shown in the examples below. INFO/AF[0] > 0.3 .. first AF value bigger than 0.3 FORMAT/AD[0:0] > 30 .. first AD value of the first sample bigger than 30 FORMAT/AD[0:1] .. first sample, second AD value FORMAT/AD[1:0] .. second sample, first AD value DP4[*] == 0 .. any DP4 value FORMAT/DP[0] > 30 .. DP of the first sample bigger than 30 FORMAT/DP[1-3] > 10 .. samples 2-4 FORMAT/DP[1-] < 7 .. all samples but the first FORMAT/DP[0,2-4] > 20 .. samples 1, 3-5 FORMAT/AD[0:1] .. first sample, second AD field FORMAT/AD[0:*], AD[0:] or AD[0] .. first sample, any AD field FORMAT/AD[*:1] or AD[:1] .. any sample, second AD field (DP4[0]+DP4[1])/(DP4[2]+DP4[3]) > 0.3 CSQ[*] ~ "missense_variant.*deleterious" * in addition to array subscripts shown above, it is possible to subscript arrays of Number=R tags by alleles found in FORMAT/GT (starting with version 1.17). For example FORMAT/AD[GT] > 10 .. require support of more than 10 reads for each allele FORMAT/AD[0:GT] > 10 .. same as above, but in the first sample sSUM(FORMAT/AD[GT]) > 20 .. require total sample depth bigger than 20 * with many samples it can be more practical to provide a file with sample names, one sample name per line GT[@samples.txt]="het" & binom(AD)<0.01 * function on FORMAT tags (over samples) and INFO tags (over vector fields): maximum; minimum; arithmetic mean (AVG is synonymous with MEAN); median; standard deviation from mean; sum; string length; absolute value; number of elements: MAX, MIN, AVG, MEAN, MEDIAN, STDEV, SUM, STRLEN, ABS, COUNT + Note that functions above evaluate to a single value across all samples and are intended to select sites, not samples, even when applied on FORMAT tags. However, when prefixed with SMPL_ (or "s" for brevity, e.g. SMPL_MAX or sMAX), they will evaluate to a vector of per-sample values when applied on FORMAT tags: SMPL_MAX, SMPL_MIN, SMPL_AVG, SMPL_MEAN, SMPL_MEDIAN, SMPL_STDEV, SMPL_SUM, sMAX, sMIN, sAVG, sMEAN, sMEDIAN, sSTDEV, sSUM * two-tailed binomial test. Note that for N=0 the test evaluates to a missing value and when FORMAT/GT is used to determine the vector indices, it evaluates to 1 for homozygous genotypes. binom(FMT/AD) .. GT can be used to determine the correct index binom(AD[0],AD[1]) .. or the fields can be given explicitly phred(binom()) .. the same as binom but phred-scaled * variables calculated on the fly if not present: number of alternate alleles; number of samples; count of alternate alleles; minor allele count (similar to AC but is always smaller than 0.5); frequency of alternate alleles (AF=AC/AN); frequency of minor alleles (MAF=MAC/AN); number of alleles in called genotypes; number of samples with missing genotype; fraction of samples with missing genotype; indel length (deletions negative, insertions positive, balanced substitutions zero) N_ALT, N_SAMPLES, AC, MAC, AF, MAF, AN, N_MISSING, F_MISSING, ILEN * the number (N_PASS) or fraction (F_PASS) of samples which pass the expression N_PASS(GQ>90 & GT!="mis") > 90 F_PASS(GQ>90 & GT!="mis") > 0.9 * custom perl filtering. Note that this command is not compiled in by default, see the section *Optional Compilation with Perl* in the INSTALL file for help and misc/demo-flt.pl for a working example. The demo defined the perl subroutine "severity" which can be invoked from the command line as follows: perl:path/to/script.pl; perl.severity(INFO/CSQ) > 3 .Notes: * String comparisons and regular expressions are case-insensitive * Comma in strings is interpreted as a separator and when multiple values are compared, the OR logic is used. Consequently, the following two expressions are equivalent but not the third: -i 'TAG="hello,world"' -i 'TAG="hello" || TAG="world"' -i 'TAG="hello" && TAG="world"' * Variables and function names are case-insensitive, but not tag names. For example, "qual" can be used instead of "QUAL", "strlen()" instead of "STRLEN()" , but not "dp" instead of "DP". * When querying multiple values, all elements are tested and the OR logic is used on the result. For example, when querying "TAG=1,2,3,4", it will be evaluated as follows: -i 'TAG[*]=1' .. true, the record will be printed -i 'TAG[*]!=1' .. true -e 'TAG[*]=1' .. false, the record will be discarded -e 'TAG[*]!=1' .. false -i 'TAG[0]=1' .. true -i 'TAG[0]!=1' .. false -e 'TAG[0]=1' .. false -e 'TAG[0]!=1' .. true * When arithmetic operators are used on vectors A and B, the following logic is used to compute the resulting vector C: - C_i = A_i + B_i when length(A)==B(A) and sets length(C)=length(A) - C_i = A_i + B_0 when length(B)=1 and sets length(C)=length(A) - C_i = A_0 + B_i when length(A)=1 and sets length(C)=length(B) - throw an error when length(A)!=length(B) AND length(A)!=1 AND length(B)!=1 *Examples:* -- MIN(DV)>5 .. selects the whole site, evaluates min across all values and samples SMPL_MIN(DV)>5 .. selects matching samples, evaluates within samples MIN(DV/DP)>0.3 MIN(DP)>10 & MIN(DV)>3 FMT/DP>10 & FMT/GQ>10 .. both conditions must be satisfied within one sample FMT/DP>10 && FMT/GQ>10 .. the conditions can be satisfied in different samples QUAL>10 | FMT/GQ>10 .. true for sites with QUAL>10 or a sample with GQ>10, but selects only samples with GQ>10 QUAL>10 || FMT/GQ>10 .. true for sites with QUAL>10 or a sample with GQ>10, plus selects all samples at such sites TYPE="snp" && QUAL>=10 && (DP4[2]+DP4[3] > 2) COUNT(GT="hom")=0 .. no homozygous genotypes at the site AVG(GQ)>50 .. average (arithmetic mean) of genotype qualities bigger than 50 ID=@file .. selects lines with ID present in the file ID!=@~/file .. skip lines with ID present in the ~/file INFO/TAG=@file .. selects lines with INFO/TAG value present in the file MAF[0]<0.05 .. select rare variants at 5% cutoff POS>=100 .. restrict your range query, e.g. 20:100-200 to strictly sites with POS in that range. -- *Shell expansion:* Note that expressions must often be quoted because some characters have special meaning in the shell. An example of expression enclosed in single quotes which cause that the whole expression is passed to the program as intended: -- bcftools view -i '%ID!="." & MAF[0]<0.01' -- Please refer to the documentation of your shell for details. [[terminology]] TERMINOLOGY ----------- The program and the documentation uses the following terminology, multiple terms can be used interchangeably for the same VCF record type -- REF ALT --------- C . .. reference allele / non-variant site / ref-only site C T .. SNP or SNV (single-nucleotide polymorphism or variant), used interchangeably CC TT .. MNP (multi-nucleotide polymorphism) CAAA C .. indel, deletion (regardless of length) C CAAA .. indel, insertion (regardless of length) C <*> .. gVCF block, the allele <*> is a placeholder for alternate allele possibly missed because of low coverage C .. synonymous to <*> C * .. overlapping deletion C .. symbolic allele, known also as 'other [than above]' -- PERFORMANCE ----------- HTSlib was designed with BCF format in mind. When parsing VCF files, all records are internally converted into BCF representation. Simple operations, like removing a single column from a VCF file, can be therefore done much faster with standard UNIX commands, such as *awk* or *cut*. Therefore it is recommended to use BCF as input/output format whenever possible to avoid large overhead of the VCF -> BCF -> VCF conversion. BUGS ---- Please report any bugs you encounter on the github website: AUTHORS ------- Heng Li from the Sanger Institute wrote the original C version of htslib, samtools and bcftools. Bob Handsaker from the Broad Institute implemented the BGZF library. Petr Danecek is maintaining and further developing bcftools, together with the rest of the https://www.sanger.ac.uk/tool/samtools-bcftools-htslib[samtools team]. Many other people contributed to the program and to the file format specifications, both directly and indirectly by providing patches, testing and reporting bugs. We thank them all. RESOURCES --------- BCFtools GitHub website: Samtools GitHub website: HTSlib GitHub website: File format specifications: BCFtools documentation: BCFtools wiki page: COPYING ------- The MIT/Expat License or GPL License, see the LICENSE document for details. 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} span.line-through { text-decoration: line-through; } bcftools-1.21/edlib.c000066400000000000000000000640741467060157400145200ustar00rootroot00000000000000/* * A cut down C translated of the C++ edlib.cpp file. * Taken from edlib v0.1.0-166-g931be2b */ #include #include #include #include #include "edlib.h" typedef uint64_t Word; static const int WORD_SIZE = 64; // Size of Word in bits static const Word WORD_1 = (Word)1; static const Word HIGH_BIT_MASK = 1LL << 63; // 100..00 //#define MAX_UCHAR 255 #define MAX_UCHAR 7 // better cache usage for our data #ifndef MAX #define MAX(a,b) ((a)>(b)?(a):(b)) #endif typedef struct Block { Word P; // Pvin Word M; // Mvin int score; // score of last cell in block; } Block; /** * Defines equality relation on alphabet characters. * By default each character is always equal only to itself, but you can also provide additional equalities. */ typedef struct EqualityDefinition { bool matrix[MAX_UCHAR + 1][MAX_UCHAR + 1]; } EqualityDefinition; static EqualityDefinition * CreateEqualityDefinition(const char *alphabet, int alphabet_size, const EdlibEqualityPair* additionalEqualities, const int additionalEqualitiesLength) { EqualityDefinition *ed = malloc(sizeof(*ed)); for (size_t i = 0; i < alphabet_size; i++) { for (size_t j = 0; j < alphabet_size; j++) { ed->matrix[i][j] = (i == j); } } if (additionalEqualities != NULL) { for (int i = 0; i < additionalEqualitiesLength; i++) { const char *firstTransformed = strchr(alphabet, additionalEqualities[i].first); const char *secondTransformed = strchr(alphabet, additionalEqualities[i].second); if (firstTransformed && alphabet_size) { ed->matrix[firstTransformed - alphabet][secondTransformed - alphabet] = ed->matrix[secondTransformed - alphabet][firstTransformed - alphabet] = true; } } } return ed; } /** * @param a Element from transformed sequence. * @param b Element from transformed sequence. * @return True if a and b are defined as equal, false otherwise. */ static inline const /* attribute pure or const? */ bool equalityDefinition_areEqual(const EqualityDefinition *ed, unsigned char a, unsigned char b) { return ed->matrix[a][b]; } static int myersCalcEditDistanceSemiGlobal(const Word* Peq, int W, int maxNumBlocks, int queryLength, const unsigned char* target, int targetLength, int k, EdlibAlignMode mode, int* bestScore_, int** positions_, int* numPositions_); static char *transformSequences(const char* queryOriginal, int queryLength, const char* targetOriginal, int targetLength, unsigned char** queryTransformed, unsigned char** targetTransformed, int *alphabet_size); static inline int ceilDiv(int x, int y); static inline unsigned char* createReverseCopy(const unsigned char* seq, int length); static inline Word* buildPeq(const int alphabetLength, const unsigned char* query, const int queryLength, const EqualityDefinition* equalityDefinition); /** * Main edlib method. */ EdlibAlignResult edlibAlign(const char* const queryOriginal, const int queryLength, const char* const targetOriginal, const int targetLength, const EdlibAlignConfig config) { EdlibAlignResult result; result.status = EDLIB_STATUS_OK; result.editDistance = -1; result.endLocations = result.startLocations = NULL; result.numLocations = 0; result.alignment = NULL; result.alignmentLength = 0; result.alphabetLength = 0; /*------------ TRANSFORM SEQUENCES AND RECOGNIZE ALPHABET -----------*/ unsigned char* query, * target; int alphabet_size; char *alphabet = transformSequences(queryOriginal, queryLength, targetOriginal, targetLength, &query, &target, &alphabet_size); result.alphabetLength = alphabet_size; /*-------------------------------------------------------*/ // Handle special situation when at least one of the sequences has length 0. if (queryLength == 0 || targetLength == 0) { if (config.mode == EDLIB_MODE_NW) { result.editDistance = MAX(queryLength, targetLength); result.endLocations = malloc(sizeof(int) * 1); result.endLocations[0] = targetLength - 1; result.numLocations = 1; } else if (config.mode == EDLIB_MODE_SHW || config.mode == EDLIB_MODE_HW) { result.editDistance = queryLength; result.endLocations = malloc(sizeof(int) * 1); result.endLocations[0] = -1; result.numLocations = 1; } else { result.status = EDLIB_STATUS_ERROR; } free(query); free(target); free(alphabet); return result; } /*--------------------- INITIALIZATION ------------------*/ int maxNumBlocks = ceilDiv(queryLength, WORD_SIZE); // bmax in Myers int W = maxNumBlocks * WORD_SIZE - queryLength; // number of redundant cells in last level blocks EqualityDefinition *equalityDefinition = CreateEqualityDefinition(alphabet, alphabet_size, config.additionalEqualities, config.additionalEqualitiesLength); Word* Peq = buildPeq(alphabet_size, query, queryLength, equalityDefinition); /*-------------------------------------------------------*/ /*------------------ MAIN CALCULATION -------------------*/ // TODO: Store alignment data only after k is determined? That could make things faster. // int positionNW; // Used only when mode is NW. // AlignmentData* alignData = NULL; bool dynamicK = false; int k = config.k; if (k < 0) { // If valid k is not given, auto-adjust k until solution is found. dynamicK = true; k = WORD_SIZE; // Gives better results than smaller k. } do { if (config.mode == EDLIB_MODE_HW || config.mode == EDLIB_MODE_SHW) { myersCalcEditDistanceSemiGlobal(Peq, W, maxNumBlocks, queryLength, target, targetLength, k, config.mode, &(result.editDistance), &(result.endLocations), &(result.numLocations)); } else { // mode == EDLIB_MODE_NW // myersCalcEditDistanceNW(Peq, W, maxNumBlocks, // queryLength, target, targetLength, // k, &(result.editDistance), &positionNW, // false, &alignData, -1); } k *= 2; } while(dynamicK && result.editDistance == -1); if (result.editDistance >= 0) { // If there is solution. // If NW mode, set end location explicitly. if (config.mode == EDLIB_MODE_NW) { result.endLocations = malloc(sizeof(int) * 1); result.endLocations[0] = targetLength - 1; result.numLocations = 1; } // Find starting locations. if (config.task == EDLIB_TASK_LOC || config.task == EDLIB_TASK_PATH) { result.startLocations = malloc(result.numLocations * sizeof(int)); if (config.mode == EDLIB_MODE_HW) { // If HW, I need to calculate start locations. const unsigned char* rTarget = createReverseCopy(target, targetLength); const unsigned char* rQuery = createReverseCopy(query, queryLength); // Peq for reversed query. Word* rPeq = buildPeq(alphabet_size, rQuery, queryLength, equalityDefinition); for (int i = 0; i < result.numLocations; i++) { int endLocation = result.endLocations[i]; if (endLocation == -1) { // NOTE: Sometimes one of optimal solutions is that query starts before target, like this: // AAGG <- target // CCTT <- query // It will never be only optimal solution and it does not happen often, however it is // possible and in that case end location will be -1. What should we do with that? // Should we just skip reporting such end location, although it is a solution? // If we do report it, what is the start location? -4? -1? Nothing? // TODO: Figure this out. This has to do in general with how we think about start // and end locations. // Also, we have alignment later relying on this locations to limit the space of it's // search -> how can it do it right if these locations are negative or incorrect? result.startLocations[i] = 0; // I put 0 for now, but it does not make much sense. } else { int bestScoreSHW, numPositionsSHW; int* positionsSHW; myersCalcEditDistanceSemiGlobal( rPeq, W, maxNumBlocks, queryLength, rTarget + targetLength - endLocation - 1, endLocation + 1, result.editDistance, EDLIB_MODE_SHW, &bestScoreSHW, &positionsSHW, &numPositionsSHW); // Taking last location as start ensures that alignment will not start with insertions // if it can start with mismatches instead. result.startLocations[i] = endLocation - positionsSHW[numPositionsSHW - 1]; free(positionsSHW); } } free((void *)rTarget); free((void *)rQuery); free(rPeq); } else { // If mode is SHW or NW for (int i = 0; i < result.numLocations; i++) { result.startLocations[i] = 0; } } } } /*-------------------------------------------------------*/ //--- Free memory ---// free(Peq); free(query); free(target); free(alphabet); free(equalityDefinition); // DestroyAlignmentData(alignData); //-------------------// return result; } /** * Build Peq table for given query and alphabet. * Peq is table of dimensions alphabetLength+1 x maxNumBlocks. * Bit i of Peq[s * maxNumBlocks + b] is 1 if i-th symbol from block b of query equals symbol s, otherwise it is 0. * NOTICE: free returned array with free()! */ static inline Word* buildPeq(const int alphabetLength, const unsigned char* const query, const int queryLength, const EqualityDefinition* equalityDefinition) { int maxNumBlocks = ceilDiv(queryLength, WORD_SIZE); // table of dimensions alphabetLength+1 x maxNumBlocks. Last symbol is wildcard. Word* Peq = malloc((alphabetLength + 1) * maxNumBlocks * sizeof(*Peq)); // Build Peq (1 is match, 0 is mismatch). NOTE: last column is wildcard(symbol that matches anything) with just 1s // Optimised Peq building avoiding branching. for (int symbol = 0; symbol < alphabetLength; symbol++) { for (int b = 0; b < maxNumBlocks; b++) { Word PeqW = 0; for (int r = (b+1) * WORD_SIZE - 1; r >= b * WORD_SIZE; r--) { PeqW = (PeqW<<1) + (r >= queryLength || equalityDefinition_areEqual(equalityDefinition, query[r], symbol)); } Peq[symbol * maxNumBlocks + b] = PeqW; } } { int symbol = alphabetLength; for (int b = 0; b < maxNumBlocks; b++) { // Last symbol is wildcard, so it is all 1s Peq[symbol * maxNumBlocks + b] = (Word)-1; } } return Peq; } /** * Returns new sequence that is reverse of given sequence. * Free returned array with free() */ static inline unsigned char* createReverseCopy(const unsigned char* const seq, const int length) { unsigned char* rSeq = malloc(length); for (int i = 0; i < length; i++) { rSeq[i] = seq[length - i - 1]; } return rSeq; } /** * Corresponds to Advance_Block function from Myers. * Calculates one word(block), which is part of a column. * Highest bit of word (one most to the left) is most bottom cell of block from column. * Pv[i] and Mv[i] define vin of cell[i]: vin = cell[i] - cell[i-1]. * @param [in] Pv Bitset, Pv[i] == 1 if vin is +1, otherwise Pv[i] == 0. * @param [in] Mv Bitset, Mv[i] == 1 if vin is -1, otherwise Mv[i] == 0. * @param [in] Eq Bitset, Eq[i] == 1 if match, 0 if mismatch. * @param [in] hin Will be +1, 0 or -1. * @param [out] PvOut Bitset, PvOut[i] == 1 if vout is +1, otherwise PvOut[i] == 0. * @param [out] MvOut Bitset, MvOut[i] == 1 if vout is -1, otherwise MvOut[i] == 0. * @param [out] hout Will be +1, 0 or -1. */ static inline int calculateBlock(Word Pv, Word Mv, Word Eq, const int hin, Word *PvOut, Word *MvOut) { // hin can be 1, -1 or 0. // 1 -> 00...01 // 0 -> 00...00 // -1 -> 11...11 (2-complement) Word hinIsNeg = (Word)(hin >> 2) & WORD_1; // 00...001 if hin is -1, 00...000 if 0 or 1 Word Xv = Eq | Mv; // This is instruction below written using 'if': if (hin < 0) Eq |= (Word)1; Eq |= hinIsNeg; Word Xh = (((Eq & Pv) + Pv) ^ Pv) | Eq; Word Ph = Mv | ~(Xh | Pv); Word Mh = Pv & Xh; int hout = 0; // This is instruction below written using 'if': if (Ph & HIGH_BIT_MASK) hout = 1; hout = (Ph & HIGH_BIT_MASK) >> (WORD_SIZE - 1); // This is instruction below written using 'if': if (Mh & HIGH_BIT_MASK) hout = -1; hout -= (Mh & HIGH_BIT_MASK) >> (WORD_SIZE - 1); Ph <<= 1; Mh <<= 1; // This is instruction below written using 'if': if (hin < 0) Mh |= (Word)1; Mh |= hinIsNeg; // This is instruction below written using 'if': if (hin > 0) Ph |= (Word)1; Ph |= (Word)((hin + 1) >> 1); *PvOut = Mh | ~(Xv | Ph); *MvOut = Ph & Xv; return hout; } /** * Does ceiling division x / y. * Note: x and y must be non-negative and x + y must not overflow. */ static inline int ceilDiv(const int x, const int y) { return x % y ? x / y + 1 : x / y; } static inline int min(const int x, const int y) { return x < y ? x : y; } /** * @param [in] block * @return Values of cells in block, starting with bottom cell in block. */ static inline int *getBlockCellValues(const Block block) { int *scores = malloc(WORD_SIZE * sizeof(*scores)); int score = block.score; Word mask = HIGH_BIT_MASK; for (int i = 0; i < WORD_SIZE - 1; i++) { scores[i] = score; if (block.P & mask) score--; if (block.M & mask) score++; mask >>= 1; } scores[WORD_SIZE - 1] = score; return scores; } /** * @param [in] block * @param [in] k * @return True if all cells in block have value larger than k, otherwise false. */ static inline bool allBlockCellsLarger(const Block block, const int k) { int *scores = getBlockCellValues(block); for (int i = 0; i < WORD_SIZE; i++) { if (scores[i] <= k) { free(scores); return false; } } free(scores); return true; } /** * Uses Myers' bit-vector algorithm to find edit distance for one of semi-global alignment methods. * @param [in] Peq Query profile. * @param [in] W Size of padding in last block. * TODO: Calculate this directly from query, instead of passing it. * @param [in] maxNumBlocks Number of blocks needed to cover the whole query. * TODO: Calculate this directly from query, instead of passing it. * @param [in] queryLength * @param [in] target * @param [in] targetLength * @param [in] k * @param [in] mode EDLIB_MODE_HW or EDLIB_MODE_SHW * @param [out] bestScore_ Edit distance. * @param [out] positions_ Array of 0-indexed positions in target at which best score was found. Make sure to free this array with free(). * @param [out] numPositions_ Number of positions in the positions_ array. * @return Status. */ static int myersCalcEditDistanceSemiGlobal( const Word* const Peq, const int W, const int maxNumBlocks, const int queryLength, const unsigned char* const target, const int targetLength, int k, const EdlibAlignMode mode, int* const bestScore_, int** const positions_, int* const numPositions_) { *positions_ = NULL; *numPositions_ = 0; // firstBlock is 0-based index of first block in Ukkonen band. // lastBlock is 0-based index of last block in Ukkonen band. int firstBlock = 0; int lastBlock = min(ceilDiv(k + 1, WORD_SIZE), maxNumBlocks) - 1; // y in Myers Block *bl; // Current block Block* blocks = malloc(maxNumBlocks * sizeof(*blocks)); // For HW, solution will never be larger then queryLength. if (mode == EDLIB_MODE_HW) { k = min(queryLength, k); } // Each STRONG_REDUCE_NUM column is reduced in more expensive way. // This gives speed up of about 2 times for small k. const int STRONG_REDUCE_NUM = 2048; // Initialize P, M and score bl = blocks; for (int b = 0; b <= lastBlock; b++) { bl->score = (b + 1) * WORD_SIZE; bl->P = (Word)(-1); // All 1s bl->M = (Word)(0); bl++; } int bestScore = -1; #define MAX_POS 100 // maximum number of positions returned. int positions[MAX_POS]; int npositions = 0; const int startHout = mode == EDLIB_MODE_HW ? 0 : 1; // If 0 then gap before query is not penalized; const unsigned char* targetChar = target; for (int c = 0; c < targetLength; c++) { // for each column const Word* Peq_c = Peq + (*targetChar) * maxNumBlocks; //----------------------- Calculate column -------------------------// int hout = startHout; bl = blocks + firstBlock; Peq_c += firstBlock; for (int b = firstBlock; b <= lastBlock; b++) { hout = calculateBlock(bl->P, bl->M, *Peq_c, hout, &bl->P, &bl->M); bl->score += hout; bl++; Peq_c++; } bl--; Peq_c--; //------------------------------------------------------------------// //---------- Adjust number of blocks according to Ukkonen ----------// if ((lastBlock < maxNumBlocks - 1) && (bl->score - hout <= k) // bl is pointing to last block && ((*(Peq_c + 1) & WORD_1) || hout < 0)) { // Peq_c is pointing to last block // If score of left block is not too big, calculate one more block lastBlock++; bl++; Peq_c++; bl->P = (Word)(-1); // All 1s bl->M = (Word)(0); bl->score = (bl - 1)->score - hout + WORD_SIZE + calculateBlock(bl->P, bl->M, *Peq_c, hout, &bl->P, &bl->M); } else { while (lastBlock >= firstBlock && bl->score >= k + WORD_SIZE) { lastBlock--; bl--; Peq_c--; } } // Every some columns, do some expensive but also more efficient block reducing. // This is important! // // Reduce the band by decreasing last block if possible. if (c % STRONG_REDUCE_NUM == 0) { while (lastBlock >= 0 && lastBlock >= firstBlock && allBlockCellsLarger(*bl, k)) { lastBlock--; bl--; Peq_c--; } } // For HW, even if all cells are > k, there still may be solution in next // column because starting conditions at upper boundary are 0. // That means that first block is always candidate for solution, // and we can never end calculation before last column. if (mode == EDLIB_MODE_HW && lastBlock == -1) { lastBlock++; bl++; Peq_c++; } // Reduce band by increasing first block if possible. Not applicable to HW. if (mode != EDLIB_MODE_HW) { while (firstBlock <= lastBlock && blocks[firstBlock].score >= k + WORD_SIZE) { firstBlock++; } if (c % STRONG_REDUCE_NUM == 0) { // Do strong reduction every some blocks while (firstBlock <= lastBlock && allBlockCellsLarger(blocks[firstBlock], k)) { firstBlock++; } } } // If band stops to exist finish if (lastBlock < firstBlock) { *bestScore_ = bestScore; if (bestScore != -1) { *positions_ = malloc(npositions * sizeof(int)); *numPositions_ = npositions; memcpy(*positions_, positions, npositions * sizeof(int)); } free(blocks); return EDLIB_STATUS_OK; } //------------------------------------------------------------------// //------------------------- Update best score ----------------------// if (lastBlock == maxNumBlocks - 1) { int colScore = bl->score; if (colScore <= k) { // Scores > k dont have correct values (so we cannot use them), but are certainly > k. // NOTE: Score that I find in column c is actually score from column c-W if (bestScore == -1 || colScore <= bestScore) { if (colScore != bestScore) { npositions = 0; bestScore = colScore; // Change k so we will look only for equal or better // scores then the best found so far. k = bestScore; } if (npositions < MAX_POS) positions[npositions++] = c - W; } } } //------------------------------------------------------------------// targetChar++; } // Obtain results for last W columns from last column. if (lastBlock == maxNumBlocks - 1) { int *blockScores = getBlockCellValues(*bl); for (int i = 0; i < W; i++) { int colScore = blockScores[i + 1]; if (colScore <= k && (bestScore == -1 || colScore <= bestScore)) { if (colScore != bestScore) { npositions = 0; k = bestScore = colScore; } if (npositions < MAX_POS) positions[npositions++] = targetLength - W + i; } } free(blockScores); } *bestScore_ = bestScore; if (bestScore != -1) { *positions_ = malloc(npositions * sizeof(int)); *numPositions_ = npositions; memcpy(*positions_, positions, npositions * sizeof(int)); } free(blocks); return EDLIB_STATUS_OK; } /** * Takes char query and char target, recognizes alphabet and transforms them into unsigned char sequences * where elements in sequences are not any more letters of alphabet, but their index in alphabet. * Most of internal edlib functions expect such transformed sequences. * This function will allocate queryTransformed and targetTransformed, so make sure to free them when done. * Example: * Original sequences: "ACT" and "CGT". * Alphabet would be recognized as "ACTG". Alphabet length = 4. * Transformed sequences: [0, 1, 2] and [1, 3, 2]. * @param [in] queryOriginal * @param [in] queryLength * @param [in] targetOriginal * @param [in] targetLength * @param [out] queryTransformed It will contain values in range [0, alphabet length - 1]. * @param [out] targetTransformed It will contain values in range [0, alphabet length - 1]. * @return Alphabet as a string of unique characters, where index of each character is its value in transformed * sequences. */ static char *transformSequences(const char* const queryOriginal, const int queryLength, const char* const targetOriginal, const int targetLength, unsigned char** const queryTransformed, unsigned char** const targetTransformed, int *alphabet_size) { // Alphabet is constructed from letters that are present in sequences. // Each letter is assigned an ordinal number, starting from 0 up to alphabetLength - 1, // and new query and target are created in which letters are replaced with their ordinal numbers. // This query and target are used in all the calculations later. *queryTransformed = malloc(sizeof(unsigned char) * queryLength); *targetTransformed = malloc(sizeof(unsigned char) * targetLength); char *alphabet = malloc(MAX_UCHAR+1), *alphabet_cp = alphabet; // Alphabet information, it is constructed on fly while transforming sequences. // letterIdx[c] is index of letter c in alphabet. unsigned char letterIdx[MAX_UCHAR + 1]; bool inAlphabet[MAX_UCHAR + 1]; // inAlphabet[c] is true if c is in alphabet for (int i = 0; i < MAX_UCHAR + 1; i++) inAlphabet[i] = false; for (int i = 0; i < queryLength; i++) { unsigned char c = queryOriginal[i]; if (!inAlphabet[c]) { inAlphabet[c] = true; letterIdx[c] = alphabet_cp - alphabet; *alphabet_cp++ = queryOriginal[i]; } (*queryTransformed)[i] = letterIdx[c]; } for (int i = 0; i < targetLength; i++) { unsigned char c = targetOriginal[i]; if (!inAlphabet[c]) { inAlphabet[c] = true; letterIdx[c] = alphabet_cp - alphabet; *alphabet_cp++ = targetOriginal[i]; } (*targetTransformed)[i] = letterIdx[c]; } *alphabet_size = alphabet_cp - alphabet; return alphabet; } EdlibAlignConfig edlibNewAlignConfig(int k, EdlibAlignMode mode, EdlibAlignTask task, const EdlibEqualityPair* additionalEqualities, int additionalEqualitiesLength) { EdlibAlignConfig config; config.k = k; config.mode = mode; config.task = task; config.additionalEqualities = additionalEqualities; config.additionalEqualitiesLength = additionalEqualitiesLength; return config; } EdlibAlignConfig edlibDefaultAlignConfig(void) { return edlibNewAlignConfig(-1, EDLIB_MODE_NW, EDLIB_TASK_DISTANCE, NULL, 0); } void edlibFreeAlignResult(EdlibAlignResult result) { if (result.endLocations) free(result.endLocations); if (result.startLocations) free(result.startLocations); if (result.alignment) free(result.alignment); } bcftools-1.21/edlib.h000066400000000000000000000254421467060157400145210ustar00rootroot00000000000000#ifndef EDLIB_H #define EDLIB_H /** * @file * @author Martin Sosic * @brief Main header file, containing all public functions and structures. */ // Define EDLIB_API macro to properly export symbols #ifdef EDLIB_SHARED # ifdef _WIN32 # ifdef EDLIB_BUILD # define EDLIB_API __declspec(dllexport) # else # define EDLIB_API __declspec(dllimport) # endif # else # define EDLIB_API __attribute__ ((visibility ("default"))) # endif #else # define EDLIB_API #endif #ifdef __cplusplus extern "C" { #endif // Status codes #define EDLIB_STATUS_OK 0 #define EDLIB_STATUS_ERROR 1 /** * Alignment methods - how should Edlib treat gaps before and after query? */ typedef enum { /** * Global method. This is the standard method. * Useful when you want to find out how similar is first sequence to second sequence. */ EDLIB_MODE_NW, /** * Prefix method. Similar to global method, but with a small twist - gap at query end is not penalized. * What that means is that deleting elements from the end of second sequence is "free"! * For example, if we had "AACT" and "AACTGGC", edit distance would be 0, because removing "GGC" from the end * of second sequence is "free" and does not count into total edit distance. This method is appropriate * when you want to find out how well first sequence fits at the beginning of second sequence. */ EDLIB_MODE_SHW, /** * Infix method. Similar as prefix method, but with one more twist - gaps at query end and start are * not penalized. What that means is that deleting elements from the start and end of second sequence is "free"! * For example, if we had ACT and CGACTGAC, edit distance would be 0, because removing CG from the start * and GAC from the end of second sequence is "free" and does not count into total edit distance. * This method is appropriate when you want to find out how well first sequence fits at any part of * second sequence. * For example, if your second sequence was a long text and your first sequence was a sentence from that text, * but slightly scrambled, you could use this method to discover how scrambled it is and where it fits in * that text. In bioinformatics, this method is appropriate for aligning read to a sequence. */ EDLIB_MODE_HW } EdlibAlignMode; /** * Alignment tasks - what do you want Edlib to do? */ typedef enum { EDLIB_TASK_DISTANCE, //!< Find edit distance and end locations. EDLIB_TASK_LOC, //!< Find edit distance, end locations and start locations. EDLIB_TASK_PATH //!< Find edit distance, end locations and start locations and alignment path. } EdlibAlignTask; /** * Describes cigar format. * @see http://samtools.github.io/hts-specs/SAMv1.pdf * @see http://drive5.com/usearch/manual/cigar.html */ typedef enum { EDLIB_CIGAR_STANDARD, //!< Match: 'M', Insertion: 'I', Deletion: 'D', Mismatch: 'M'. EDLIB_CIGAR_EXTENDED //!< Match: '=', Insertion: 'I', Deletion: 'D', Mismatch: 'X'. } EdlibCigarFormat; // Edit operations. #define EDLIB_EDOP_MATCH 0 //!< Match. #define EDLIB_EDOP_INSERT 1 //!< Insertion to target = deletion from query. #define EDLIB_EDOP_DELETE 2 //!< Deletion from target = insertion to query. #define EDLIB_EDOP_MISMATCH 3 //!< Mismatch. /** * @brief Defines two given characters as equal. */ typedef struct { char first; char second; } EdlibEqualityPair; /** * @brief Configuration object for edlibAlign() function. */ typedef struct { /** * Set k to non-negative value to tell edlib that edit distance is not larger than k. * Smaller k can significantly improve speed of computation. * If edit distance is larger than k, edlib will set edit distance to -1. * Set k to negative value and edlib will internally auto-adjust k until score is found. */ int k; /** * Alignment method. * EDLIB_MODE_NW: global (Needleman-Wunsch) * EDLIB_MODE_SHW: prefix. Gap after query is not penalized. * EDLIB_MODE_HW: infix. Gaps before and after query are not penalized. */ EdlibAlignMode mode; /** * Alignment task - tells Edlib what to calculate. Less to calculate, faster it is. * EDLIB_TASK_DISTANCE - find edit distance and end locations of optimal alignment paths in target. * EDLIB_TASK_LOC - find edit distance and start and end locations of optimal alignment paths in target. * EDLIB_TASK_PATH - find edit distance, alignment path (and start and end locations of it in target). */ EdlibAlignTask task; /** * List of pairs of characters, where each pair defines two characters as equal. * This way you can extend edlib's definition of equality (which is that each character is equal only * to itself). * This can be useful if you have some wildcard characters that should match multiple other characters, * or e.g. if you want edlib to be case insensitive. * Can be set to NULL if there are none. */ const EdlibEqualityPair* additionalEqualities; /** * Number of additional equalities, which is non-negative number. * 0 if there are none. */ int additionalEqualitiesLength; } EdlibAlignConfig; /** * Helper method for easy construction of configuration object. * @return Configuration object filled with given parameters. */ EDLIB_API EdlibAlignConfig edlibNewAlignConfig( int k, EdlibAlignMode mode, EdlibAlignTask task, const EdlibEqualityPair* additionalEqualities, int additionalEqualitiesLength ); /** * @return Default configuration object, with following defaults: * k = -1, mode = EDLIB_MODE_NW, task = EDLIB_TASK_DISTANCE, no additional equalities. */ EDLIB_API EdlibAlignConfig edlibDefaultAlignConfig(void); /** * Container for results of alignment done by edlibAlign() function. */ typedef struct { /** * EDLIB_STATUS_OK or EDLIB_STATUS_ERROR. If error, all other fields will have undefined values. */ int status; /** * -1 if k is non-negative and edit distance is larger than k. */ int editDistance; /** * Array of zero-based positions in target where optimal alignment paths end. * If gap after query is penalized, gap counts as part of query (NW), otherwise not. * Set to NULL if edit distance is larger than k. * If you do not free whole result object using edlibFreeAlignResult(), do not forget to use free(). */ int* endLocations; /** * Array of zero-based positions in target where optimal alignment paths start, * they correspond to endLocations. * If gap before query is penalized, gap counts as part of query (NW), otherwise not. * Set to NULL if not calculated or if edit distance is larger than k. * If you do not free whole result object using edlibFreeAlignResult(), do not forget to use free(). */ int* startLocations; /** * Number of end (and start) locations. */ int numLocations; /** * Alignment is found for first pair of start and end locations. * Set to NULL if not calculated. * Alignment is sequence of numbers: 0, 1, 2, 3. * 0 stands for match. * 1 stands for insertion to target. * 2 stands for insertion to query. * 3 stands for mismatch. * Alignment aligns query to target from beginning of query till end of query. * If gaps are not penalized, they are not in alignment. * If you do not free whole result object using edlibFreeAlignResult(), do not forget to use free(). */ unsigned char* alignment; /** * Length of alignment. */ int alignmentLength; /** * Number of different characters in query and target together. */ int alphabetLength; } EdlibAlignResult; /** * Frees memory in EdlibAlignResult that was allocated by edlib. * If you do not use it, make sure to free needed members manually using free(). */ EDLIB_API void edlibFreeAlignResult(EdlibAlignResult result); /** * Aligns two sequences (query and target) using edit distance (levenshtein distance). * Through config parameter, this function supports different alignment methods (global, prefix, infix), * as well as different modes of search (tasks). * It always returns edit distance and end locations of optimal alignment in target. * It optionally returns start locations of optimal alignment in target and alignment path, * if you choose appropriate tasks. * @param [in] query First sequence. * @param [in] queryLength Number of characters in first sequence. * @param [in] target Second sequence. * @param [in] targetLength Number of characters in second sequence. * @param [in] config Additional alignment parameters, like alignment method and wanted results. * @return Result of alignment, which can contain edit distance, start and end locations and alignment path. * Make sure to clean up the object using edlibFreeAlignResult() or by manually freeing needed members. */ EDLIB_API EdlibAlignResult edlibAlign( const char* query, int queryLength, const char* target, int targetLength, const EdlibAlignConfig config ); /** * Builds cigar string from given alignment sequence. * @param [in] alignment Alignment sequence. * 0 stands for match. * 1 stands for insertion to target. * 2 stands for insertion to query. * 3 stands for mismatch. * @param [in] alignmentLength * @param [in] cigarFormat Cigar will be returned in specified format. * @return Cigar string. * I stands for insertion. * D stands for deletion. * X stands for mismatch. (used only in extended format) * = stands for match. (used only in extended format) * M stands for (mis)match. (used only in standard format) * String is null terminated. * Needed memory is allocated and given pointer is set to it. * Do not forget to free it later using free()! */ EDLIB_API char* edlibAlignmentToCigar( const unsigned char* alignment, int alignmentLength, EdlibCigarFormat cigarFormat ); #ifdef __cplusplus } #endif #endif // EDLIB_H bcftools-1.21/em.c000066400000000000000000000212351467060157400140320ustar00rootroot00000000000000/* em.c -- mathematical functions. Copyright (C) 2010, 2011 Broad Institute. Portions copyright (C) 2013-2014 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include "kmin.h" #include "call.h" #define ITER_MAX 50 #define ITER_TRY 10 #define EPS 1e-5 extern double kf_gammaq(double, double); /* Generic routines */ // estimate site allele frequency in a very naive and inaccurate way static double est_freq(int n, const double *pdg) { int i, gcnt[3], tmp1; // get a rough estimate of the genotype frequency gcnt[0] = gcnt[1] = gcnt[2] = 0; for (i = 0; i < n; ++i) { const double *p = pdg + i * 3; if (p[0] != 1. || p[1] != 1. || p[2] != 1.) { int which = p[0] > p[1]? 0 : 1; which = p[which] > p[2]? which : 2; ++gcnt[which]; } } tmp1 = gcnt[0] + gcnt[1] + gcnt[2]; return (tmp1 == 0)? -1.0 : (.5 * gcnt[1] + gcnt[2]) / tmp1; } /* Single-locus EM */ typedef struct { int beg, end; const double *pdg; } minaux1_t; static double prob1(double f, void *data) { minaux1_t *a = (minaux1_t*)data; double p = 1., l = 0., f3[3]; int i; // printf("brent %lg\n", f); if (f < 0 || f > 1) return 1e300; f3[0] = (1.-f)*(1.-f); f3[1] = 2.*f*(1.-f); f3[2] = f*f; for (i = a->beg; i < a->end; ++i) { const double *pdg = a->pdg + i * 3; p *= pdg[0] * f3[0] + pdg[1] * f3[1] + pdg[2] * f3[2]; if (p < 1e-200) l -= log(p), p = 1.; } return l - log(p); } // one EM iteration for allele frequency estimate static double freq_iter(double *f, const double *_pdg, int beg, int end) { double f0 = *f, f3[3], err; int i; // printf("em %lg\n", *f); f3[0] = (1.-f0)*(1.-f0); f3[1] = 2.*f0*(1.-f0); f3[2] = f0*f0; for (i = beg, f0 = 0.; i < end; ++i) { const double *pdg = _pdg + i * 3; f0 += (pdg[1] * f3[1] + 2. * pdg[2] * f3[2]) / (pdg[0] * f3[0] + pdg[1] * f3[1] + pdg[2] * f3[2]); } f0 /= (end - beg) * 2; err = fabs(f0 - *f); *f = f0; return err; } /* The following function combines EM and Brent's method. When the signal from * the data is strong, EM is faster but sometimes, EM may converge very slowly. * When this happens, we switch to Brent's method. The idea is learned from * Rasmus Nielsen. */ static double freqml(double f0, int beg, int end, const double *pdg) { int i; double f; for (i = 0, f = f0; i < ITER_TRY; ++i) if (freq_iter(&f, pdg, beg, end) < EPS) break; if (i == ITER_TRY) { // haven't converged yet; try Brent's method minaux1_t a; a.beg = beg; a.end = end; a.pdg = pdg; kmin_brent(prob1, f0 == f? .5*f0 : f0, f, (void*)&a, EPS, &f); } return f; } // one EM iteration for genotype frequency estimate static double g3_iter(double g[3], const double *_pdg, int beg, int end) { double err, gg[3]; int i; gg[0] = gg[1] = gg[2] = 0.; // printf("%lg,%lg,%lg\n", g[0], g[1], g[2]); for (i = beg; i < end; ++i) { double sum, tmp[3]; const double *pdg = _pdg + i * 3; tmp[0] = pdg[0] * g[0]; tmp[1] = pdg[1] * g[1]; tmp[2] = pdg[2] * g[2]; sum = (tmp[0] + tmp[1] + tmp[2]) * (end - beg); gg[0] += tmp[0] / sum; gg[1] += tmp[1] / sum; gg[2] += tmp[2] / sum; } err = fabs(gg[0] - g[0]) > fabs(gg[1] - g[1])? fabs(gg[0] - g[0]) : fabs(gg[1] - g[1]); err = err > fabs(gg[2] - g[2])? err : fabs(gg[2] - g[2]); g[0] = gg[0]; g[1] = gg[1]; g[2] = gg[2]; return err; } // perform likelihood ratio test static double lk_ratio_test(int n, int n1, const double *pdg, double f3[3][3]) { double r; int i; for (i = 0, r = 1.; i < n1; ++i) { const double *p = pdg + i * 3; r *= (p[0] * f3[1][0] + p[1] * f3[1][1] + p[2] * f3[1][2]) / (p[0] * f3[0][0] + p[1] * f3[0][1] + p[2] * f3[0][2]); } for (; i < n; ++i) { const double *p = pdg + i * 3; r *= (p[0] * f3[2][0] + p[1] * f3[2][1] + p[2] * f3[2][2]) / (p[0] * f3[0][0] + p[1] * f3[0][1] + p[2] * f3[0][2]); } return r; } // x[0]: ref frequency // x[1..3]: alt-alt, alt-ref, ref-ref frequenc // x[4]: HWE P-value // x[5..6]: group1 freq, group2 freq // x[7]: 1-degree P-value // x[8]: 2-degree P-value int bcf_em1(call_t *call, const bcf1_t *rec, int n1, int flag, double x[10]) { double *pdg; int i, n; //, n2; if (rec->n_allele < 2) return -1; // one allele only // initialization if (n1 < 0 || n1 > rec->n_sample) n1 = 0; if (flag & 1<<7) flag |= 7<<5; // compute group freq if LRT is required if (flag & 0xf<<1) flag |= 0xf<<1; n = rec->n_sample; //n2 = n - n1; pdg = call->pdg; if (pdg == 0) return -1; for (i = 0; i < 10; ++i) x[i] = -1.; // set to negative { if ((x[0] = est_freq(n, pdg)) < 0.) return -1; // no data x[0] = freqml(x[0], 0, n, pdg); } if (flag & (0xf<<1|3<<8)) { // estimate the genotype frequency and test HWE double *g = x + 1, f3[3], r; f3[0] = g[0] = (1 - x[0]) * (1 - x[0]); f3[1] = g[1] = 2 * x[0] * (1 - x[0]); f3[2] = g[2] = x[0] * x[0]; for (i = 0; i < ITER_MAX; ++i) if (g3_iter(g, pdg, 0, n) < EPS) break; // Hardy-Weinberg equilibrium (HWE) for (i = 0, r = 1.; i < n; ++i) { double *p = pdg + i * 3; r *= (p[0] * g[0] + p[1] * g[1] + p[2] * g[2]) / (p[0] * f3[0] + p[1] * f3[1] + p[2] * f3[2]); } x[4] = kf_gammaq(.5, log(r)); } if ((flag & 7<<5) && n1 > 0 && n1 < n) { // group frequency x[5] = freqml(x[0], 0, n1, pdg); x[6] = freqml(x[0], n1, n, pdg); } if ((flag & 1<<7) && n1 > 0 && n1 < n) { // 1-degree P-value double f[3], f3[3][3], tmp; f[0] = x[0]; f[1] = x[5]; f[2] = x[6]; for (i = 0; i < 3; ++i) f3[i][0] = (1-f[i])*(1-f[i]), f3[i][1] = 2*f[i]*(1-f[i]), f3[i][2] = f[i]*f[i]; tmp = log(lk_ratio_test(n, n1, pdg, f3)); if (tmp < 0) tmp = 0; x[7] = kf_gammaq(.5, tmp); } if ((flag & 3<<8) && n1 > 0 && n1 < n) { // 2-degree P-value double g[3][3], tmp; for (i = 0; i < 3; ++i) memcpy(g[i], x + 1, 3 * sizeof(double)); for (i = 0; i < ITER_MAX; ++i) if (g3_iter(g[1], pdg, 0, n1) < EPS) break; for (i = 0; i < ITER_MAX; ++i) if (g3_iter(g[2], pdg, n1, n) < EPS) break; tmp = log(lk_ratio_test(n, n1, pdg, g)); if (tmp < 0) tmp = 0; x[8] = kf_gammaq(1., tmp); } return 0; } /* Two-locus EM (LD) */ #define _G1(h, k) ((h>>1&1) + (k>>1&1)) #define _G2(h, k) ((h&1) + (k&1)) #if 0 // 0: the previous site; 1: the current site static int pair_freq_iter(int n, double *pdg[2], double f[4]) { double ff[4]; int i, k, h; // printf("%lf,%lf,%lf,%lf\n", f[0], f[1], f[2], f[3]); memset(ff, 0, 4 * sizeof(double)); for (i = 0; i < n; ++i) { double *p[2], sum, tmp; p[0] = pdg[0] + i * 3; p[1] = pdg[1] + i * 3; for (k = 0, sum = 0.; k < 4; ++k) for (h = 0; h < 4; ++h) sum += f[k] * f[h] * p[0][_G1(k,h)] * p[1][_G2(k,h)]; for (k = 0; k < 4; ++k) { tmp = f[0] * (p[0][_G1(0,k)] * p[1][_G2(0,k)] + p[0][_G1(k,0)] * p[1][_G2(k,0)]) + f[1] * (p[0][_G1(1,k)] * p[1][_G2(1,k)] + p[0][_G1(k,1)] * p[1][_G2(k,1)]) + f[2] * (p[0][_G1(2,k)] * p[1][_G2(2,k)] + p[0][_G1(k,2)] * p[1][_G2(k,2)]) + f[3] * (p[0][_G1(3,k)] * p[1][_G2(3,k)] + p[0][_G1(k,3)] * p[1][_G2(k,3)]); ff[k] += f[k] * tmp / sum; } } for (k = 0; k < 4; ++k) f[k] = ff[k] / (2 * n); return 0; } #endif bcftools-1.21/extsort.c000066400000000000000000000174111467060157400151420ustar00rootroot00000000000000/* ext-sort.h -- sort on disk Copyright (C) 2020-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include // for unlink() #include // for chmod() #include #include #ifdef _WIN32 #include #endif #include "bcftools.h" #include "extsort.h" #include "kheap.h" typedef struct { extsort_t *es; // this is to get access to extsort_cmp_f from kheap int fd; char *fname; void *dat; } blk_t; static inline int blk_is_smaller(blk_t **aptr, blk_t **bptr); KHEAP_INIT(blk, blk_t*, blk_is_smaller) /* defines khp_blk_t */ struct _extsort_t { size_t dat_size, mem, max_mem; char *tmp_prefix; extsort_cmp_f cmp; size_t nbuf, mbuf, nblk; blk_t **blk; void **buf, *tmp_dat; khp_blk_t *bhp; }; static inline int blk_is_smaller(blk_t **aptr, blk_t **bptr) { blk_t *a = *aptr; blk_t *b = *bptr; int ret = a->es->cmp(&a->dat,&b->dat); if ( ret < 0 ) return 1; return 0; } size_t parse_mem_string(const char *str); void extsort_set(extsort_t *es, extsort_opt_t key, void *value) { if ( key==DAT_SIZE ) { es->dat_size = *((size_t*)value); return; } if ( key==MAX_MEM ) { es->max_mem = parse_mem_string(*((const char**)value)); if ( es->max_mem <=0 ) error("Could not parse the memory string, expected positive number: %s\n",*((const char**)value)); return; } if ( key==TMP_PREFIX ) { es->tmp_prefix = init_tmp_prefix(*((const char**)value)); return; } if ( key==FUNC_CMP ) { es->cmp = *((extsort_cmp_f*)value); return; } } extsort_t *extsort_alloc(void) { extsort_t *es = (extsort_t*) calloc(1,sizeof(*es)); es->max_mem = 100e6; return es; } void extsort_init(extsort_t *es) { assert( es->cmp ); assert( es->dat_size ); if ( !es->tmp_prefix ) es->tmp_prefix = init_tmp_prefix(NULL); es->tmp_dat = malloc(es->dat_size); } void extsort_destroy(extsort_t *es) { int i; for (i=0; inblk; i++) { blk_t *blk = es->blk[i]; if ( blk->fd!=-1 ) #ifdef _WIN32 _close(blk->fd); #else close(blk->fd); #endif free(blk->fname); free(blk->dat); free(blk); } free(es->tmp_dat); free(es->tmp_prefix); free(es->blk); khp_destroy(blk, es->bhp); free(es); } static void _buf_flush(extsort_t *es) { int i; if ( !es->nbuf ) return; qsort(es->buf, es->nbuf, sizeof(void*), es->cmp); es->nblk++; es->blk = (blk_t**) realloc(es->blk, sizeof(blk_t*)*es->nblk); es->blk[es->nblk-1] = (blk_t*) calloc(1,sizeof(blk_t)); blk_t *blk = es->blk[es->nblk-1]; blk->es = es; blk->dat = malloc(es->dat_size); blk->fname = strdup(es->tmp_prefix); #ifdef _WIN32 for (i=0; i<100000; i++) { memcpy(blk->fname,es->tmp_prefix,strlen(es->tmp_prefix)); mktemp(blk->fname); blk->fd = _open(blk->fname, O_RDWR|O_CREAT|O_EXCL|O_BINARY|O_TEMPORARY, 0600); if ( blk->fd==-1 ) { if ( errno==EEXIST ) continue; error("Error: failed to open a temporary file %s\n",blk->fname); } break; } if ( !blk->fd ) error("Error: failed to create a unique temporary file name from %s\n",es->tmp_prefix); if ( _chmod(blk->fname, S_IRUSR|S_IWUSR)!=0 ) error("Error: failed to set permissions of the temporary file %s\n",blk->fname); #else if ( (blk->fd = mkstemp(blk->fname))==-1 ) error("Error: failed to open a temporary file %s\n",blk->fname); if ( fchmod(blk->fd,S_IRUSR|S_IWUSR)!=0 ) error("Error: failed to set permissions of the temporary file %s\n",blk->fname); unlink(blk->fname); // should auto delete when closed on linux, the descriptor remains open #endif for (i=0; inbuf; i++) { #ifdef _WIN32 if ( _write(blk->fd, es->buf[i], es->dat_size)!=es->dat_size ) error("Error: failed to write %zu bytes to the temporary file %s\n",es->dat_size,blk->fname); #else if ( write(blk->fd, es->buf[i], es->dat_size)!=es->dat_size ) error("Error: failed to write %zu bytes to the temporary file %s\n",es->dat_size,blk->fname); #endif free(es->buf[i]); } #ifdef _WIN32 if ( _lseek(blk->fd,0,SEEK_SET)!=0 ) error("Error: failed to lseek() to the start of the temporary file %s\n", blk->fname); #else if ( lseek(blk->fd,0,SEEK_SET)!=0 ) error("Error: failed to lseek() to the start of the temporary file %s\n", blk->fname); #endif es->nbuf = 0; es->mem = 0; } void extsort_push(extsort_t *es, void *dat) { int delta = sizeof(void*) + es->dat_size; if ( es->nbuf && es->mem + delta > es->max_mem ) _buf_flush(es); es->nbuf++; es->mem += delta; hts_expand(void*, es->nbuf, es->mbuf, es->buf); es->buf[es->nbuf-1] = dat; } // return number of elements read static ssize_t _blk_read(extsort_t *es, blk_t *blk) { ssize_t ret = 0; if ( blk->fd==-1 ) return ret; #ifdef _WIN32 ret = _read(blk->fd, blk->dat, es->dat_size); #else ret = read(blk->fd, blk->dat, es->dat_size); #endif if ( ret < 0 ) error("Error: failed to read from the temporary file %s\n", blk->fname); if ( ret == 0 ) { #ifdef _WIN32 if ( _close(blk->fd)!=0 ) error("Error: failed to close the temporary file %s\n", blk->fname); #else if ( close(blk->fd)!=0 ) error("Error: failed to close the temporary file %s\n", blk->fname); #endif blk->fd = -1; return ret; } if ( ret < es->dat_size ) error("Error: failed to read %zu bytes from the temporary file %s\n",es->dat_size,blk->fname); return ret; } void extsort_sort(extsort_t *es) { _buf_flush(es); free(es->buf); es->buf = NULL; es->bhp = khp_init(blk); // open all blocks, read one record from each, create a heap int i; for (i=0; inblk; i++) { blk_t *blk = es->blk[i]; #ifdef _WIN32 if ( _lseek(blk->fd,0,SEEK_SET)!=0 ) error("Error: failed to lseek() to the start of the temporary file %s\n", blk->fname); #else if ( lseek(blk->fd,0,SEEK_SET)!=0 ) error("Error: failed to lseek() to the start of the temporary file %s\n", blk->fname); #endif int ret = _blk_read(es, blk); if ( ret ) khp_insert(blk, es->bhp, &blk); } } void *extsort_shift(extsort_t *es) { if ( !es->bhp->ndat ) return NULL; blk_t *blk = es->bhp->dat[0]; // swap the pointer which keeps the location of user data so that it is not overwritten by the next read void *tmp = es->tmp_dat; es->tmp_dat = blk->dat; blk->dat = tmp; khp_delete(blk, es->bhp); int ret = _blk_read(es, blk); if ( ret ) khp_insert(blk, es->bhp, &blk); return es->tmp_dat; } bcftools-1.21/extsort.h000066400000000000000000000042041467060157400151430ustar00rootroot00000000000000/* ext-sort.h -- sort on disk Copyright (C) 2020 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __EXTSORT_H__ #define __EXTSORT_H__ //todo: return status to all functions typedef struct _extsort_t extsort_t; typedef int (*extsort_cmp_f) (const void *aptr, const void *bptr); // Modes of operation typedef enum { DAT_SIZE, // size_t .. assuming constant size records for now TMP_PREFIX, // const char* .. prefix of temporary files, XXXXXX will be appended MAX_MEM, // const char* .. maximum memory to use, e.g. 100MB FUNC_CMP, // extsort_cmp_f .. sort function } extsort_opt_t; #define extsort_set_opt(es,type,key,value) { type tmp = value; extsort_set(es, key, (void*)&tmp); } extsort_t *extsort_alloc(void); void extsort_set(extsort_t *es, extsort_opt_t key, void *value); void extsort_init(extsort_t *es); void extsort_push(extsort_t *es, void *dat); // dat will be freed by extsort later void extsort_sort(extsort_t *es); void *extsort_shift(extsort_t *es); void extsort_destroy(extsort_t *es); #endif bcftools-1.21/filter.c000066400000000000000000004624171467060157400147310ustar00rootroot00000000000000/* filter.c -- filter expressions. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #ifndef _WIN32 #include #endif #include #include #include #include #include #include #include "config.h" #include "filter.h" #include "bcftools.h" #if ENABLE_PERL_FILTERS // Work around clang warning problems # if defined(__clang__) # define PERL_GCC_BRACE_GROUPS_FORBIDDEN # endif # define filter_t perl_filter_t # include # include # undef filter_t # define my_perl perl static int filter_ninit = 0; #endif #ifndef __FUNCTION__ # define __FUNCTION__ __func__ #endif typedef struct _token_t { // read-only values, same for all VCF lines int tok_type; // one of the TOK_* keys below int nargs; // with TOK_PERLSUB the first argument is the name of the subroutine char *key; // set only for string constants, otherwise NULL char *tag; // for debugging and printout only, VCF tag name double threshold; // filtering threshold int is_constant; // the threshold is set int hdr_id, hl_type, ht_type; // BCF header lookup ID and one of BCF_HL_* types and BCF_HT_* types int idx; // 0-based index to VCF vectors, // -2: list (e.g. [0,1,2] or [1..3] or [1..] or any field[*], which is equivalent to [0..]) // -3: select indices on the fly based on values in GT int *idxs; // set indexes to 0 to exclude, to 1 to include, and last element negative if unlimited; used by VCF retrievers only int nidxs, nuidxs; // size of idxs array and the number of elements set to 1 uint8_t *usmpl; // bitmask of used samples as set by idx, set for FORMAT fields, NULL otherwise int nsamples; // number of samples for format fields, 0 for info and other fields void (*setter)(filter_t *, bcf1_t *, struct _token_t *); int (*func)(filter_t *, bcf1_t *, struct _token_t *rtok, struct _token_t **stack, int nstack); void (*comparator)(struct _token_t *, struct _token_t *, struct _token_t *rtok, bcf1_t *); void *hash; // test presence of str value in the hash via comparator regex_t *regex; // precompiled regex for string comparison int iext; // for the use with filter_test_ext(), 1-based index to external values, 0=don't use // modified on filter evaluation at each VCF line double *values; kstring_t str_value; int is_str, is_missing; // is_missing is set only for constants, variables are controlled via nvalues int pass_site; // -1 not applicable, 0 fails, >0 pass uint8_t *pass_samples; // status of individual samples int nvalues, mvalues; // number of used values: n=0 for missing values, n=1 for scalars, for strings n=str_value.l int nval1; // number of per-sample fields or string length } token_t; struct _filter_t { bcf_hdr_t *hdr; char *str; int nfilters; token_t *filters, **flt_stack; // filtering input tokens (in RPN) and evaluation stack int32_t *tmpi; float *tmpf; kstring_t tmps; int max_unpack, mtmpi, mtmpf, nsamples; struct { bcf1_t *line; int32_t *buf, nbuf, mbuf; // GTs as obtained by bcf_get_genotypes() uint64_t *mask; // GTs as mask, e.g 0/0 is 1; 0/1 is 3, max 63 unique alleles } cached_GT; #if ENABLE_PERL_FILTERS PerlInterpreter *perl; #endif char **undef_tag, **used_tag; int nundef_tag, nused_tag; int status, exit_on_error; int n_ext; // number of external values to fill via filter_test_ext() int *ext; // types of external values to fill via filter_test_ext() }; #define TOK_VAL 0 #define TOK_LFT 1 // ( #define TOK_RGT 2 // ) #define TOK_LE 3 // less or equal #define TOK_LT 4 // less than #define TOK_EQ 5 // equal #define TOK_BT 6 // bigger than #define TOK_BE 7 // bigger or equal #define TOK_NE 8 // not equal #define TOK_OR 9 // | #define TOK_AND 10 // & #define TOK_ADD 11 // + #define TOK_SUB 12 // - #define TOK_MULT 13 // * #define TOK_DIV 14 // / #define TOK_MAX 15 #define TOK_MIN 16 #define TOK_AVG 17 #define TOK_AND_VEC 18 // && (operator applied in samples) #define TOK_OR_VEC 19 // || (operator applied in samples) #define TOK_LIKE 20 // ~ regular expression #define TOK_NLIKE 21 // !~ regular expression #define TOK_SUM 22 #define TOK_ABS 23 #define TOK_LEN 24 #define TOK_FUNC 25 #define TOK_CNT 26 #define TOK_PERLSUB 27 #define TOK_BINOM 28 #define TOK_PHRED 29 #define TOK_MEDIAN 30 #define TOK_STDEV 31 #define TOK_sMAX 32 #define TOK_sMIN 33 #define TOK_sAVG 34 #define TOK_sMEDIAN 35 #define TOK_sSTDEV 36 #define TOK_sSUM 37 #define TOK_IN 38 // contains, e.g. FILTER~"A" #define TOK_NOT_IN 39 // does not contain, e.g. FILTER!~"A" #define TOK_MODULO 40 // % #define TOK_EXT 41 // external values set before each filter_test_ext() call, can be one of {},{str},{int},{float} // 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 // ( ) [ < = > ] ! | & + - * / M m a A O ~ ^ S . l f c p b P i s % static int op_prec[] = {0,1,1,5,5,5,5,5,5,2,3, 6, 6, 7, 7, 8, 8, 8, 3, 2, 5, 5, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 8, 7, 0}; #define TOKEN_STRING "x()[<=>]!|&+-*/MmaAO~^S.lfcpis" // this is only for debugging, not maintained diligently static void cmp_vector_strings(token_t *atok, token_t *btok, token_t *rtok); inline static void tok_init_samples(token_t *atok, token_t *btok, token_t *rtok); // Return negative values if it is a function with variable number of arguments static int filters_next_token(char **str, int *len) { char *tmp = *str; while ( *tmp && isspace(*tmp) ) tmp++; *str = tmp; *len = 0; // test for doubles: d.ddde[+-]dd if ( isdigit(*str[0]) || *str[0]=='.' ) // strtod would eat +/- { double HTS_UNUSED v = strtod(*str, &tmp); if ( *str!=tmp && (!tmp[0] || !isalnum(tmp[0])) ) { *len = tmp - (*str); return TOK_VAL; } tmp = *str; } if ( !strncasecmp(tmp,"SMPL_MAX(",9) ) { (*str) += 8; return TOK_sMAX; } if ( !strncasecmp(tmp,"SMPL_MIN(",9) ) { (*str) += 8; return TOK_sMIN; } if ( !strncasecmp(tmp,"SMPL_MEAN(",10) ) { (*str) += 9; return TOK_sAVG; } if ( !strncasecmp(tmp,"SMPL_MEDIAN(",12) ) { (*str) += 11; return TOK_sMEDIAN; } if ( !strncasecmp(tmp,"SMPL_AVG(",9) ) { (*str) += 8; return TOK_sAVG; } if ( !strncasecmp(tmp,"SMPL_STDEV(",11) ) { (*str) += 10; return TOK_sSTDEV; } if ( !strncasecmp(tmp,"SMPL_SUM(",9) ) { (*str) += 8; return TOK_sSUM; } if ( !strncasecmp(tmp,"sMAX(",5) ) { (*str) += 4; return TOK_sMAX; } if ( !strncasecmp(tmp,"sMIN(",5) ) { (*str) += 4; return TOK_sMIN; } if ( !strncasecmp(tmp,"sMEAN(",6) ) { (*str) += 5; return TOK_sAVG; } if ( !strncasecmp(tmp,"sMEDIAN(",8) ) { (*str) += 7; return TOK_sMEDIAN; } if ( !strncasecmp(tmp,"sAVG(",5) ) { (*str) += 4; return TOK_sAVG; } if ( !strncasecmp(tmp,"sSTDEV(",7) ) { (*str) += 6; return TOK_sSTDEV; } if ( !strncasecmp(tmp,"sSUM(",5) ) { (*str) += 4; return TOK_sSUM; } if ( !strncasecmp(tmp,"MAX(",4) ) { (*str) += 3; return TOK_MAX; } if ( !strncasecmp(tmp,"MIN(",4) ) { (*str) += 3; return TOK_MIN; } if ( !strncasecmp(tmp,"MEAN(",5) ) { (*str) += 4; return TOK_AVG; } if ( !strncasecmp(tmp,"MEDIAN(",7) ) { (*str) += 6; return TOK_MEDIAN; } if ( !strncasecmp(tmp,"AVG(",4) ) { (*str) += 3; return TOK_AVG; } if ( !strncasecmp(tmp,"STDEV(",6) ) { (*str) += 5; return TOK_STDEV; } if ( !strncasecmp(tmp,"SUM(",4) ) { (*str) += 3; return TOK_SUM; } if ( !strncasecmp(tmp,"ABS(",4) ) { (*str) += 3; return TOK_ABS; } if ( !strncasecmp(tmp,"COUNT(",4) ) { (*str) += 5; return TOK_CNT; } if ( !strncasecmp(tmp,"STRLEN(",7) ) { (*str) += 6; return TOK_LEN; } if ( !strncasecmp(tmp,"BINOM(",6) ) { (*str) += 5; return -TOK_BINOM; } if ( !strncasecmp(tmp,"PHRED(",6) ) { (*str) += 5; return TOK_PHRED; } if ( !strncasecmp(tmp,"%MAX(",5) ) { (*str) += 4; return TOK_MAX; } // for backward compatibility if ( !strncasecmp(tmp,"%MIN(",5) ) { (*str) += 4; return TOK_MIN; } // for backward compatibility if ( !strncasecmp(tmp,"%AVG(",5) ) { (*str) += 4; return TOK_AVG; } // for backward compatibility if ( !strncasecmp(tmp,"%SUM(",5) ) { (*str) += 4; return TOK_SUM; } // for backward compatibility if ( !strncasecmp(tmp,"INFO/",5) ) tmp += 5; if ( !strncasecmp(tmp,"FORMAT/",7) ) tmp += 7; if ( !strncasecmp(tmp,"FMT/",4) ) tmp += 4; if ( !strncasecmp(tmp,"PERL.",5) ) { (*str) += 5; return -TOK_PERLSUB; } if ( !strncasecmp(tmp,"N_PASS(",7) ) { *len = 6; (*str) += 6; return -TOK_FUNC; } if ( !strncasecmp(tmp,"F_PASS(",7) ) { *len = 6; (*str) += 6; return -TOK_FUNC; } if ( !strncasecmp(tmp,"%ILEN",5) ) { *len = 5; return TOK_VAL; } // to be able to distinguish between INFO/ILEN and on-the-fly ILEN if ( !strncasecmp(tmp,"{}",2) ) { *len = 2; return TOK_EXT; } if ( !strncasecmp(tmp,"{STR}",5) ) { *len = 5; return TOK_EXT; } if ( !strncasecmp(tmp,"{INT}",5) ) { *len = 5; return TOK_EXT; } if ( !strncasecmp(tmp,"{FLOAT}",7) ) { *len = 7; return TOK_EXT; } if ( tmp[0]=='@' ) // file name { while ( *tmp && !isspace(*tmp) && *tmp!='=' && *tmp!='!' ) tmp++; *len = tmp - (*str); return TOK_VAL; } int square_brackets = 0; while ( tmp[0] ) { if ( !square_brackets ) { if ( tmp[0]=='"' ) break; if ( tmp[0]=='\'' ) break; if ( isspace(tmp[0]) ) break; if ( tmp[0]=='<' ) break; if ( tmp[0]=='>' ) break; if ( tmp[0]=='=' ) break; if ( tmp[0]=='!' ) break; if ( tmp[0]=='&' ) break; if ( tmp[0]=='|' ) break; if ( tmp[0]=='(' ) break; if ( tmp[0]==')' ) break; if ( tmp[0]=='+' ) break; if ( tmp[0]=='*' ) break; if ( tmp[0]=='-' ) break; if ( tmp[0]=='/' ) break; if ( tmp[0]=='~' ) break; if ( tmp[0]=='%' ) break; } if ( tmp[0]==']' ) { if (square_brackets) tmp++; break; } if ( tmp[0]=='[' ) square_brackets++; tmp++; } if ( tmp > *str ) { *len = tmp - (*str); return TOK_VAL; } if ( tmp[0]=='"' || tmp[0]=='\'' ) { int quote = tmp[0]; tmp++; while ( *tmp && tmp[0]!=quote ) tmp++; if ( !*tmp ) return -1; // missing quotes *len = tmp - (*str) + 1; return TOK_VAL; } if ( tmp[0]=='!' ) { if ( tmp[1]=='=' ) { (*str) += 2; return TOK_NE; } if ( tmp[1]=='~' ) { (*str) += 2; return TOK_NLIKE; } } if ( tmp[0]=='<' ) { if ( tmp[1]=='=' ) { (*str) += 2; return TOK_LE; } (*str) += 1; return TOK_LT; } if ( tmp[0]=='>' ) { if ( tmp[1]=='=' ) { (*str) += 2; return TOK_BE; } (*str) += 1; return TOK_BT; } if ( tmp[0]=='=' ) { if ( tmp[1]=='=' ) { (*str) += 2; return TOK_EQ; } (*str) += 1; return TOK_EQ; } if ( tmp[0]=='(' ) { (*str) += 1; return TOK_LFT; } if ( tmp[0]==')' ) { (*str) += 1; return TOK_RGT; } if ( tmp[0]=='&' && tmp[1]=='&' ) { (*str) += 2; return TOK_AND_VEC; } if ( tmp[0]=='|' && tmp[1]=='|' ) { (*str) += 2; return TOK_OR_VEC; } if ( tmp[0]=='&' ) { (*str) += 1; return TOK_AND; } if ( tmp[0]=='|' ) { (*str) += 1; return TOK_OR; } if ( tmp[0]=='+' ) { (*str) += 1; return TOK_ADD; } if ( tmp[0]=='-' ) { (*str) += 1; return TOK_SUB; } if ( tmp[0]=='*' ) { (*str) += 1; return TOK_MULT; } if ( tmp[0]=='/' ) { (*str) += 1; return TOK_DIV; } if ( tmp[0]=='~' ) { (*str) += 1; return TOK_LIKE; } if ( tmp[0]=='%' ) { (*str) += 1; return TOK_MODULO; } *len = tmp - (*str); return TOK_VAL; } #define FILTER_OK 0 #define FILTER_ERR_UNKN_TAGS 1 #define FILTER_ERR_OTHER 2 static void filter_add_undef_tag(filter_t *filter, char *str) { int i; for (i=0; inundef_tag; i++) if ( !strcmp(str,filter->undef_tag[i]) ) break; if ( inundef_tag ) return; filter->nundef_tag++; filter->undef_tag = (char**)realloc(filter->undef_tag,sizeof(*filter->undef_tag)*filter->nundef_tag); if ( !filter->undef_tag ) error("Could not allocate memory\n"); filter->undef_tag[filter->nundef_tag-1] = strdup(str); if ( !filter->undef_tag[filter->nundef_tag-1] ) error("Could not allocate memory\n"); } const char **filter_list_undef_tags(filter_t *filter, int *ntags) { *ntags = filter->nundef_tag; return (const char**)filter->undef_tag; } static void filter_add_used_tag(filter_t *filter, const char *prefix, char *str) { int i; kstring_t tmp = {0,0,0}; if ( prefix ) kputs(prefix,&tmp); kputs(str,&tmp); for (i=0; inused_tag; i++) if ( !strcmp(tmp.s,filter->used_tag[i]) ) break; if ( inused_tag ) { free(tmp.s); return; } filter->nused_tag++; filter->used_tag = (char**)realloc(filter->used_tag,sizeof(*filter->used_tag)*filter->nused_tag); if ( !filter->used_tag ) error("Could not allocate memory\n"); filter->used_tag[filter->nused_tag-1] = tmp.s; if ( !filter->used_tag[filter->nused_tag-1] ) error("Could not allocate memory\n"); } const char **filter_list_used_tags(filter_t *filter, int *ntags) { *ntags = filter->nused_tag; return (const char**)filter->used_tag; } /* Simple path expansion, expands ~/, ~user, $var. The result must be freed by the caller. Based on jkb's staden code with some adjustments. https://sourceforge.net/p/staden/code/HEAD/tree/staden/trunk/src/Misc/getfile.c#l123 */ char *expand_path(char *path) { kstring_t str = {0,0,0}; if ( path[0] == '~' ) { if ( !path[1] || path[1] == '/' ) { #ifdef _WIN32 kputs(getenv("HOMEDRIVE"), &str); kputs(getenv("HOMEPATH"), &str); #else // ~ or ~/path kputs(getenv("HOME"), &str); if ( path[1] ) kputs(path+1, &str); #endif } #ifndef _WIN32 else { // user name: ~pd3/path char *end = path; while ( *end && *end!='/' ) end++; kputsn(path+1, end-path-1, &str); struct passwd *pwentry = getpwnam(str.s); str.l = 0; if ( !pwentry ) kputsn(path, end-path, &str); else kputs(pwentry->pw_dir, &str); kputs(end, &str); } #endif return ks_release(&str); } if ( path[0] == '$' ) { char *var = getenv(path+1); if ( var ) { kputs(var, &str); return ks_release(&str); } } return strdup(path); } static int filters_cache_genotypes(filter_t *flt, bcf1_t *line) { if ( flt->cached_GT.line==line ) return flt->cached_GT.nbuf > 0 ? 0 : -1; flt->cached_GT.line = line; flt->cached_GT.nbuf = bcf_get_genotypes(flt->hdr, line, &flt->cached_GT.buf, &flt->cached_GT.mbuf); if ( flt->cached_GT.nbuf<=0 ) return -1; if ( !flt->cached_GT.mask ) { flt->cached_GT.mask = (uint64_t*) malloc(sizeof(*flt->cached_GT.mask)*flt->nsamples); if ( !flt->cached_GT.mask ) error("Could not alloc %zu bytes\n",sizeof(*flt->cached_GT.mask)*flt->nsamples); } int i,j, ngt1 = flt->cached_GT.nbuf / line->n_sample; for (i=0; in_sample; i++) { int32_t *ptr = flt->cached_GT.buf + i*ngt1; flt->cached_GT.mask[i] = 0; for (j=0; j 63 ) { static int warned = 0; if ( !warned ) { fprintf(stderr,"Too many alleles, skipping GT filtering at this site %s:%"PRId64". " "(This warning is printed only once.)\n", bcf_seqname(flt->hdr,line),line->pos+1); warned = 1; } flt->cached_GT.nbuf = 0; return -1; } flt->cached_GT.mask[i] |= 1<qual; if ( bcf_float_is_missing(*ptr) ) bcf_double_set_missing(tok->values[0]); else tok->values[0] = (double)line->qual; tok->nvalues = 1; } static void filters_set_type(filter_t *flt, bcf1_t *line, token_t *tok) { tok->values[0] = bcf_get_variant_types(line); if ( !tok->values[0] ) tok->values[0] = 1; // mistake in htslib: VCF_* should start with 1 else tok->values[0] = ((int)tok->values[0]) << 1; tok->nvalues = 1; } static void filters_set_info(filter_t *flt, bcf1_t *line, token_t *tok) { assert( tok->hdr_id >=0 ); int i; for (i=0; in_info; i++) if ( line->d.info[i].key == tok->hdr_id ) break; if ( i==line->n_info ) tok->nvalues = tok->str_value.l = 0; else if ( line->d.info[i].type==BCF_BT_CHAR ) { int n = line->d.info[i].len; if ( n >= tok->str_value.m ) { tok->str_value.m = n + 1; tok->str_value.s = (char*) realloc(tok->str_value.s, tok->str_value.m); if ( !tok->str_value.s ) error("Failed to alloc %d bytes\n", (int)tok->str_value.m); } memcpy(tok->str_value.s, line->d.info[i].vptr, n); tok->str_value.s[n] = 0; tok->nvalues = tok->str_value.l = n; } else if ( line->d.info[i].type==BCF_BT_FLOAT ) { if ( bcf_float_is_missing(line->d.info[i].v1.f) ) tok->nvalues = 0; else { tok->values[0] = line->d.info[i].v1.f; tok->nvalues = 1; } tok->str_value.l = 0; } else { tok->str_value.l = 0; if ( line->d.info[i].type==BCF_BT_INT8 && line->d.info[i].v1.i==bcf_int8_missing ) tok->nvalues = 0; else if ( line->d.info[i].type==BCF_BT_INT16 && line->d.info[i].v1.i==bcf_int16_missing ) tok->nvalues = 0; else if ( line->d.info[i].type==BCF_BT_INT32 && line->d.info[i].v1.i==bcf_int32_missing ) tok->nvalues = 0; else { tok->values[0] = line->d.info[i].v1.i; tok->nvalues = 1; } } } static void filters_cmp_bit_and(token_t *atok, token_t *btok, token_t *rtok, bcf1_t *line) { int a = (int)(atok->nvalues?atok->values[0]:atok->threshold); int b = (int)(btok->nvalues?btok->values[0]:btok->threshold); if ( rtok->tok_type==TOK_LIKE ) rtok->pass_site = a&b ? 1 : 0; else rtok->pass_site = a&b ? 0 : 1; } static void filters_cmp_filter(token_t *atok, token_t *btok, token_t *rtok, bcf1_t *line) { // the btok values contain FILTER ids obtained by parsing the user expression int i,j; if ( rtok->tok_type==TOK_NOT_IN ) // fail if the query expression is a subset of the VCF FILTER { if ( !btok->nvalues ) // the query expression is ".", pass everything unless the VCF is also "." { if ( line->d.n_flt ) rtok->pass_site = 1; return; } if ( !line->d.n_flt ) // no filters at this VCF line and the query expression has a value { rtok->pass_site = 1; return; } for (j=0; jnvalues; j++) // some query expression value must be absent from VCF in order to pass { for (i=0; id.n_flt; i++) if ( btok->values[j]==line->d.flt[i] ) break; if ( i==line->d.n_flt ) break; // the query is not in the VCF } if ( j!=btok->nvalues ) rtok->pass_site = 1; return; } else if ( rtok->tok_type==TOK_IN ) { if ( !btok->nvalues ) // the query expression is ".", fail everything unless the VCF is also "." { if ( !line->d.n_flt ) rtok->pass_site = 1; return; } if ( !line->d.n_flt ) return; // no filters at this VCF line and the query expression has a value for (j=0; jnvalues; j++) // all of the query values must be present in the VCF in order to pass { for (i=0; id.n_flt; i++) if ( btok->values[j]==line->d.flt[i] ) break; if ( i==line->d.n_flt ) break; // the query is not in the VCF } if ( j==btok->nvalues ) rtok->pass_site = 1; return; } else if ( rtok->tok_type==TOK_NE ) // require anything but exact match { if ( btok->nvalues != line->d.n_flt ) { rtok->pass_site = 1; return; } if ( !btok->nvalues ) return; for (j=0; jnvalues; j++) // some of the query values must be absent from the VCF in order to pass { for (i=0; id.n_flt; i++) if ( btok->values[j]==line->d.flt[i] ) break; if ( i==line->d.n_flt ) break; // the query is not in the VCF } if ( j!=btok->nvalues ) rtok->pass_site = 1; return; } else if ( rtok->tok_type==TOK_EQ ) // require exact match { if ( btok->nvalues != line->d.n_flt ) return; if ( !btok->nvalues ) { rtok->pass_site = 1; return; } for (j=0; jnvalues; j++) // all of the query values must be present in the VCF in order to pass { for (i=0; id.n_flt; i++) if ( btok->values[j]==line->d.flt[i] ) break; if ( i==line->d.n_flt ) break; // the query is not in the VCF } if ( j==btok->nvalues ) rtok->pass_site = 1; return; } else error("Only ==, !=, ~, and !~ operators are supported for FILTER\n"); return; } static void filters_cmp_string_hash(token_t *atok, token_t *btok, token_t *rtok, bcf1_t *line) { if ( btok->hash ) { token_t *tmp = atok; atok = btok; btok = tmp; } if ( rtok->tok_type!=TOK_EQ && rtok->tok_type!=TOK_NE ) error("Only == and != operators are supported for strings read from a file\n"); // INFO if ( !btok->nsamples ) { // there is only one string value, e.g. STR[1]=@list.txt if ( btok->idx >= 0 ) { int ret = btok->str_value.s ? khash_str2int_has_key(atok->hash, btok->str_value.s) : 0; if ( rtok->tok_type==TOK_NE ) ret = ret ? 0 : 1; rtok->pass_site = ret; return; } // there can be multiple comma-separated string values, e.g. STR=@list.txt or STR[*]=@list.txt int ret = 0; char *ptr = btok->str_value.s; while ( *ptr ) { char *eptr = ptr + 1; while ( *eptr && *eptr!=',' ) eptr++; char keep = *eptr; *eptr = 0; ret |= khash_str2int_has_key(atok->hash, ptr); *eptr = keep; if ( !keep ) break; ptr = eptr + 1; } if ( rtok->tok_type==TOK_NE ) ret = ret ? 0 : 1; rtok->pass_site = ret; return; } // FORMAT tok_init_samples(atok, btok, rtok); rtok->pass_site = 0; int i; // there is only one string value, e.g. FMT/STR[*:1]=@list.txt if ( btok->idx >= 0 ) { for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; char *str = btok->str_value.s + i*btok->nval1; char keep = str[btok->nval1]; str[btok->nval1] = 0; int ret = khash_str2int_has_key(atok->hash, str); str[btok->nval1] = keep; if ( rtok->tok_type==TOK_NE ) ret = ret ? 0 : 1; rtok->pass_samples[i] = ret; rtok->pass_site |= ret; } return; } // there can be multiple comma-separated string values, e.g. FMT/STR=@list.txt for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; char *str = btok->str_value.s + i*btok->nval1; char keep = str[btok->nval1]; str[btok->nval1] = 0; // now str contains the block of per-sample comma-separated strings to loop over int ret = 0; char *ptr = str; while ( *ptr ) { char *eptr = ptr + 1; while ( *eptr && *eptr!=',' ) eptr++; char keep0 = *eptr; *eptr = 0; ret |= khash_str2int_has_key(atok->hash, ptr); *eptr = keep0; if ( !keep0 ) break; ptr = eptr + 1; } str[btok->nval1] = keep; if ( rtok->tok_type==TOK_NE ) ret = ret ? 0 : 1; rtok->pass_samples[i] = ret; rtok->pass_site |= ret; } } static void filters_cmp_id(token_t *atok, token_t *btok, token_t *rtok, bcf1_t *line) { if ( btok->hash ) { token_t *tmp = atok; atok = btok; btok = tmp; } char *id = line->d.id; int pass = 0; while ( id ) { char *ep = strchr(id,';'); if ( ep ) *ep = 0; if ( atok->hash ) { if ( rtok->tok_type!=TOK_EQ && rtok->tok_type!=TOK_NE ) error("Only == and != operators are supported for strings read from a file\n"); pass = khash_str2int_has_key(atok->hash, id); } else { if ( !btok->str_value.l ) error("Error occurred while evaluating the expression\n"); if ( rtok->tok_type==TOK_EQ || rtok->tok_type==TOK_NE ) pass = strcmp(btok->str_value.s,id) ? 0 : 1; else { if ( rtok->tok_type!=TOK_LIKE && rtok->tok_type!=TOK_NLIKE ) error("Only the following operators are supported for querying ID: ==, !=, ~, !~; the operator type %d is not supported (%p %p)\n", rtok->tok_type,atok->regex,btok->regex); regex_t *regex = atok->regex ? atok->regex : (btok->regex ? btok->regex : NULL); if ( !regex ) error("fixme: regex initialization failed\n"); pass = regexec(regex,id, 0,NULL,0) ? 0 : 1; } } if ( ep ) { *ep = ';'; id = ep + 1; } if ( pass || !ep ) break; } if ( rtok->tok_type==TOK_NE || rtok->tok_type==TOK_NE) pass = pass ? 0 : 1; rtok->pass_site = pass; } /** * bcf_get_info_value() - get single INFO value, int64_t or double * @line: BCF line * @info_id: tag ID, as returned by bcf_hdr_id2int * @ivec: 0-based index to retrieve, -1 when single value is expected * @vptr: pointer to memory location of sufficient size to accommodate * info_id's type * * The returned value is -1 if tag is not present, 0 if present but * values is missing or ivec is out of range, and 1 on success. */ static int bcf_get_info_value(bcf1_t *line, int info_id, int ivec, void *value) { int j; for (j=0; jn_info; j++) if ( line->d.info[j].key == info_id ) break; if ( j==line->n_info ) return -1; bcf_info_t *info = &line->d.info[j]; if ( info->len == 1 ) { if ( info->type==BCF_BT_FLOAT ) *((double*)value) = info->v1.f; else if ( info->type==BCF_BT_INT8 || info->type==BCF_BT_INT16 || info->type==BCF_BT_INT32 ) *((int64_t*)value) = info->v1.i; return 1; } if ( ivec<0 ) ivec = 0; if ( ivec>=info->len) return 0; #define BRANCH(type_t, convert, is_missing, is_vector_end, out_type_t) { \ uint8_t *p = info->vptr; \ for (j=0; jtype) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, int64_t); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, int64_t); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, val==bcf_int32_missing, val==bcf_int32_vector_end, int64_t); break; case BCF_BT_FLOAT: BRANCH(float, le_to_float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), double); break; default: fprintf(stderr,"todo: type %d\n", info->type); exit(1); break; } #undef BRANCH return -1; // this shouldn't happen } static void filters_set_chrom(filter_t *flt, bcf1_t *line, token_t *tok) { tok->str_value.l = 0; kputs(bcf_seqname(flt->hdr,line), &tok->str_value); tok->nvalues = tok->str_value.l; tok->is_str = 1; } static void filters_set_pos(filter_t *flt, bcf1_t *line, token_t *tok) { tok->values[0] = line->pos+1; tok->nvalues = 1; } static void filters_set_info_int(filter_t *flt, bcf1_t *line, token_t *tok) { if ( tok->idx==-2 ) { tok->nvalues = bcf_get_info_int32(flt->hdr,line,tok->tag,&flt->tmpi,&flt->mtmpi); if ( tok->nvalues<=0 ) tok->nvalues = 0; else { hts_expand(double,tok->nvalues,tok->mvalues,tok->values); int i, j = 0, end = tok->idxs[tok->nidxs-1] < 0 ? tok->nvalues - 1 : tok->nidxs - 1; if ( end >= tok->nvalues ) end = tok->nvalues - 1; for (i=0; i<=end; i++) if ( i>=tok->nidxs || tok->idxs[i] ) tok->values[j++] = flt->tmpi[i]; tok->nvalues = j; } } else { int64_t value = 0; if ( bcf_get_info_value(line,tok->hdr_id,tok->idx,&value) <= 0 ) tok->nvalues = 0; else { tok->values[0] = value; tok->nvalues = 1; } } } static void filters_set_info_float(filter_t *flt, bcf1_t *line, token_t *tok) { if ( tok->idx==-2 ) { tok->nvalues = bcf_get_info_float(flt->hdr,line,tok->tag,&flt->tmpf,&flt->mtmpf); if ( tok->nvalues<=0 ) tok->nvalues = 0; else { hts_expand(double,tok->nvalues,tok->mvalues,tok->values); int i, j = 0, end = tok->idxs[tok->nidxs-1] < 0 ? tok->nvalues - 1 : tok->nidxs - 1; if ( end >= tok->nvalues ) end = tok->nvalues - 1; for (i=0; i<=end; i++) if ( i>=tok->nidxs || tok->idxs[i] ) { if ( bcf_float_is_missing(flt->tmpf[i]) ) bcf_double_set_missing(tok->values[j]); else tok->values[j] = flt->tmpf[i]; j++; } tok->nvalues = j; } } else { double value; if ( bcf_get_info_value(line,tok->hdr_id,tok->idx,&value) <= 0 ) tok->nvalues = 0; else { tok->values[0] = value; tok->nvalues = 1; } } } static void filters_set_info_string(filter_t *flt, bcf1_t *line, token_t *tok) { int32_t m = tok->str_value.m; int n = bcf_get_info_string(flt->hdr,line,tok->tag,&tok->str_value.s,&m); tok->str_value.m = m; if ( n<0 ) { tok->nvalues = tok->str_value.l = 0; return; } if ( tok->idx>=0 ) { // get ith field (i=tok->idx) int i = 0; char *ss = tok->str_value.s, *se = tok->str_value.s + n; while ( ssidx ) { if ( *ss==',' ) i++; ss++; } if ( ss==se || i!=tok->idx ) { tok->nvalues = tok->str_value.l = 0; return; } se = ss; while ( se - tok->str_value.s < n && *se!=',' ) se++; if ( ss==tok->str_value.s ) *se = 0; else { memmove(tok->str_value.s, ss, se-ss); tok->str_value.s[se-ss] = 0; } tok->str_value.l = se - ss; } else if ( tok->idx==-2 && tok->idxs[0]==-1 ) // keep all values, TAG[*] tok->str_value.l = n; else if ( tok->idx==-2 ) { flt->tmps.l = 0; ks_resize(&flt->tmps, n); int i, iend = tok->idxs[tok->nidxs-1] < 0 ? n - 1 : tok->nidxs - 1; if ( iend >= n ) iend = n - 1; char *beg = tok->str_value.s, *dst = flt->tmps.s; for (i=0; i<=iend; i++) { char *end = beg; while ( *end && *end!=',' ) end++; if ( i>=tok->nidxs || tok->idxs[i] ) { memcpy(dst, beg, end - beg); dst += end - beg; dst[0] = ','; dst++; } beg = end+1; } dst[0] = 0; tok->str_value.l = dst - flt->tmps.s; #define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } SWAP(char *, flt->tmps.s, tok->str_value.s); SWAP(size_t, flt->tmps.m, tok->str_value.m); } tok->nvalues = tok->str_value.l; } static void filters_set_info_flag(filter_t *flt, bcf1_t *line, token_t *tok) { int j; for (j=0; jn_info; j++) if ( line->d.info[j].key == tok->hdr_id ) break; tok->values[0] = j==line->n_info ? 0 : 1; tok->nvalues = 1; } static void filters_set_format_int(filter_t *flt, bcf1_t *line, token_t *tok) { if ( line->n_sample != tok->nsamples ) error("Incorrect number of FORMAT fields at %s:%"PRId64" .. %s, %d vs %d\n", bcf_seqname(flt->hdr,line),(int64_t) line->pos+1,tok->tag,line->n_sample,tok->nsamples); int nvals; if ( (nvals=bcf_get_format_int32(flt->hdr,line,tok->tag,&flt->tmpi,&flt->mtmpi))<0 ) { tok->nvalues = 0; return; } int i, nsrc1 = nvals / tok->nsamples; tok->nval1 = tok->idx >= 0 ? 1 : (tok->nuidxs ? tok->nuidxs : nsrc1); tok->nvalues = tok->nval1*tok->nsamples; hts_expand(double, tok->nvalues, tok->mvalues, tok->values); if ( tok->idx >= 0 ) // scalar or vector index { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; int32_t *ptr = flt->tmpi + i*nsrc1; if ( tok->idx>=nsrc1 || ptr[tok->idx]==bcf_int32_missing ) bcf_double_set_missing(tok->values[i]); else if ( ptr[tok->idx]==bcf_int32_vector_end ) bcf_double_set_vector_end(tok->values[i]); else tok->values[i] = ptr[tok->idx]; } } else if ( tok->idx==-3 ) { if ( filters_cache_genotypes(flt,line)!=0 ) { tok->nvalues = 0; return; } for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; int32_t *src = flt->tmpi + i*nsrc1; double *dst = tok->values + i*tok->nval1; int k, j = 0; for (k=0; kcached_GT.mask[i] & (1<nval1; j++) bcf_double_set_vector_end(dst[j]); } } else { int kend = tok->idxs[tok->nidxs-1] < 0 ? tok->nval1 : tok->nidxs; for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; int32_t *src = flt->tmpi + i*nsrc1; double *dst = tok->values + i*tok->nval1; int k, j = 0; for (k=0; knidxs && !tok->idxs[k] ) continue; if ( src[k]==bcf_int32_missing ) bcf_double_set_missing(dst[j]); else if ( src[k]==bcf_int32_vector_end ) bcf_double_set_vector_end(dst[j]); else dst[j] = src[k]; j++; } if ( j==0 ) { bcf_double_set_missing(dst[j]); j++; } while (j < tok->nval1) { bcf_double_set_vector_end(dst[j]); j++; } } } } static void filters_set_format_float(filter_t *flt, bcf1_t *line, token_t *tok) { if ( line->n_sample != tok->nsamples ) error("Incorrect number of FORMAT fields at %s:%"PRId64" .. %s, %d vs %d\n", bcf_seqname(flt->hdr,line),(int64_t) line->pos+1,tok->tag,line->n_sample,tok->nsamples); int nvals; if ( (nvals=bcf_get_format_float(flt->hdr,line,tok->tag,&flt->tmpf,&flt->mtmpf))<0 ) { tok->nvalues = 0; return; } int i, nsrc1 = nvals / tok->nsamples; tok->nval1 = tok->idx >= 0 ? 1 : (tok->nuidxs ? tok->nuidxs : nsrc1); tok->nvalues = tok->nval1*tok->nsamples; hts_expand(double, tok->nvalues, tok->mvalues, tok->values); if ( tok->idx >= 0 ) // scalar or vector index { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; float *ptr = flt->tmpf + i*nsrc1; if ( tok->idx>=nsrc1 || bcf_float_is_missing(ptr[tok->idx]) ) bcf_double_set_missing(tok->values[i]); else if ( bcf_float_is_vector_end(ptr[tok->idx]) ) bcf_double_set_vector_end(tok->values[i]); else tok->values[i] = ptr[tok->idx]; } } else if ( tok->idx==-3 ) { if ( filters_cache_genotypes(flt,line)!=0 ) { tok->nvalues = 0; return; } for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; float *src = flt->tmpf + i*nsrc1; double *dst = tok->values + i*tok->nval1; int k, j = 0; for (k=0; kcached_GT.mask[i] & (1<nval1; j++) bcf_double_set_vector_end(dst[j]); } } else { int kend = tok->idxs[tok->nidxs-1] < 0 ? tok->nval1 : tok->nidxs; for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; float *src = flt->tmpf + i*nsrc1; double *dst = tok->values + i*tok->nval1; int k, j = 0; for (k=0; knidxs && !tok->idxs[k] ) continue; if ( bcf_float_is_missing(src[k]) ) bcf_double_set_missing(dst[j]); else if ( bcf_float_is_vector_end(src[k]) ) bcf_double_set_vector_end(dst[j]); else dst[j] = src[k]; j++; } if ( j==0 ) { bcf_double_set_missing(dst[j]); j++; } while (j < tok->nval1) { bcf_double_set_vector_end(dst[j]); j++; } } } } static void filters_set_format_string(filter_t *flt, bcf1_t *line, token_t *tok) { if ( line->n_sample != tok->nsamples ) error("Incorrect number of FORMAT fields at %s:%"PRId64" .. %s, %d vs %d\n", bcf_seqname(flt->hdr,line),(int64_t) line->pos+1,tok->tag,line->n_sample,tok->nsamples); int i, ndim = tok->str_value.m; int nstr = bcf_get_format_char(flt->hdr, line, tok->tag, &tok->str_value.s, &ndim); tok->str_value.m = tok->str_value.l = ndim; kputc(0,&tok->str_value); // append the nul byte tok->str_value.l = tok->nvalues = 0; if ( nstr<0 ) return; if ( tok->idx==-3 && filters_cache_genotypes(flt,line)!=0 ) return; tok->nvalues = tok->str_value.l = nstr; tok->nval1 = nstr / tok->nsamples; for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; char *src = tok->str_value.s + i*tok->nval1, *dst = src; int ibeg = 0; int idx = 0; // idx-th field while ( ibeg < tok->nval1 ) { int iend = ibeg; while ( iend < tok->nval1 && src[iend] && src[iend]!=',' ) iend++; int keep = 0; if ( tok->idx >= 0 ) // single index, given explicitly, e.g. AD[:1] { if ( tok->idx==idx ) keep = 1; } else if ( tok->idx == -3 ) // given by GT index, e.g. AD[:GT] { if ( flt->cached_GT.mask[i] & (1<nidxs ) { if ( tok->idxs[idx] != 0 ) keep = 1; } else if ( tok->idxs[tok->nidxs-1] < 0 ) keep = 1; } if ( keep ) { if ( ibeg!=0 ) memmove(dst, src+ibeg, iend-ibeg+1); dst += iend - ibeg + 1; if ( tok->idx>=0 ) break; } if ( !src[iend] ) break; ibeg = iend + 1; idx++; } if ( dst==src ) { dst[0] = '.'; dst+=2; } if ( dst - src < tok->nval1 ) memset(dst-1, 0, tok->nval1 - (dst - src)); } } static void _filters_set_genotype(filter_t *flt, bcf1_t *line, token_t *tok, int type) { bcf_fmt_t *fmt = bcf_get_fmt(flt->hdr, line, "GT"); if ( !fmt ) { tok->nvalues = tok->str_value.l = 0; return; } int i,j, nsmpl = bcf_hdr_nsamples(flt->hdr), nvals1 = type==2 ? 3 : 4; if ( tok->str_value.m <= nvals1*nsmpl ) { tok->str_value.m = nvals1*nsmpl + 1; tok->str_value.s = (char*)realloc(tok->str_value.s, tok->str_value.m); } #define BRANCH_INT(type_t, convert, vector_end) \ { \ for (i=0; in_sample; i++) \ { \ uint8_t *ptr = fmt->p + i*fmt->size; \ int is_het = 0, has_ref = 0, missing = 0, jal = 0; \ for (j=0; jn; j++) \ { \ type_t ial = convert(&ptr[j * sizeof(type_t)]); \ if ( ial==vector_end ) break; /* smaller ploidy */ \ if ( bcf_gt_is_missing(ial) ) { missing=1; break; } /* missing allele */ \ if ( bcf_gt_allele(ial)==0 ) has_ref = 1; \ if ( j>0 ) \ { \ if ( bcf_gt_allele(ial)!=bcf_gt_allele(jal) ) is_het = 1; \ } \ jal = ial; \ } \ char *dst = &tok->str_value.s[nvals1*i]; \ if ( type==4 ) \ { \ if ( !j || missing ) dst[0]='m', dst[1]='i', dst[2]='s', dst[3] = 0; /* mis, missing genotype */ \ else if ( !has_ref ) dst[0]='a', dst[1]='l', dst[2]='t', dst[3] = 0; /* alt, no ref, must have alt allele */ \ else if ( !is_het ) dst[0]='r', dst[1]='e', dst[2]='f', dst[3] = 0; /* ref, must be ref-only, no alt alelle */ \ else dst[0]='a', dst[1]='l', dst[2]='t', dst[3] = 0; /* alt, is het, has alt allele */ \ } \ else if ( !j || missing ) dst[0]='.', dst[1]=0; /* ., missing genotype */ \ else if ( type==3 ) \ { \ if ( j==1 ) dst[0]='h', dst[1]='a', dst[2]='p', dst[3] = 0; /* hap, haploid */ \ else if ( !is_het ) dst[0]='h', dst[1]='o', dst[2]='m', dst[3] = 0; /* hom */ \ else dst[0]='h', dst[1]='e', dst[2]='t', dst[3] = 0; /* het */ \ } \ else \ { \ if ( j==1 ) \ { \ if ( has_ref ) dst[0]='r', dst[1]=0; /* r, haploid */ \ else dst[0]='a', dst[1]=0; /* a, haploid */ \ } \ else if ( !is_het ) \ { \ if ( has_ref ) dst[0]='r', dst[1]='r', dst[2] = 0; /* rr */ \ else dst[0]='a', dst[1]='a', dst[2] = 0; /* aa */ \ } \ else \ { \ if ( has_ref ) dst[0]='r', dst[1]='a', dst[2] = 0; /* ra */ \ else dst[0]='a', dst[1]='A', dst[2] = 0; /* aA */ \ } \ } \ } \ } switch (fmt->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, le_to_i8, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, le_to_i16, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, le_to_i32, bcf_int32_vector_end); break; default: error("The GT type is not lineognised: %d at %s:%"PRId64"\n",fmt->type, bcf_seqname(flt->hdr,line),(int64_t) line->pos+1); break; } #undef BRANCH_INT assert( tok->nsamples == nsmpl ); tok->nvalues = tok->str_value.l = nvals1*nsmpl; tok->str_value.s[tok->str_value.l] = 0; tok->nval1 = nvals1; } static void filters_set_genotype2(filter_t *flt, bcf1_t *line, token_t *tok) { _filters_set_genotype(flt, line, tok, 2); } // rr, ra, aa, aA etc static void filters_set_genotype3(filter_t *flt, bcf1_t *line, token_t *tok) { _filters_set_genotype(flt, line, tok, 3); } // hap, hom, het static void filters_set_genotype4(filter_t *flt, bcf1_t *line, token_t *tok) { _filters_set_genotype(flt, line, tok, 4); } // mis, alt, ref static void filters_set_genotype_string(filter_t *flt, bcf1_t *line, token_t *tok) { bcf_fmt_t *fmt = bcf_get_fmt(flt->hdr, line, "GT"); if ( !fmt ) { tok->nvalues = 0; return; } int i, blen = 4, nsmpl = line->n_sample; gt_length_too_big: tok->str_value.l = 0; for (i=0; istr_value.l; bcf_format_gt(fmt, i, &tok->str_value); kputc_(0, &tok->str_value); if ( tok->str_value.l - plen > blen ) { // too many alternate alleles or ploidy is too large, the genotype does not fit // three characters ("0/0" vs "10/10"). blen *= 2; goto gt_length_too_big; } plen = tok->str_value.l - plen; while ( plen < blen ) { kputc_(0, &tok->str_value); plen++; } } assert( tok->nsamples == nsmpl ); tok->nvalues = tok->str_value.l; tok->nval1 = blen; } static void filters_set_ilen(filter_t *flt, bcf1_t *line, token_t *tok) { tok->nvalues = line->n_allele - 1; hts_expand(double,tok->nvalues,tok->mvalues,tok->values); int i, rlen = strlen(line->d.allele[0]); for (i=1; in_allele; i++) { if ( line->d.allele[i][0]=='<' ) { bcf_double_set_missing(tok->values[i-1]); continue; } int alen = strlen(line->d.allele[i]); tok->values[i-1] = alen - rlen; } } static void filters_set_ref_string(filter_t *flt, bcf1_t *line, token_t *tok) { tok->str_value.l = 0; kputs(line->d.allele[0], &tok->str_value); tok->nvalues = tok->str_value.l; } static void filters_set_alt_string(filter_t *flt, bcf1_t *line, token_t *tok) { tok->str_value.l = 0; if ( tok->idx>=0 ) { if ( line->n_allele > tok->idx + 1 ) kputs(line->d.allele[tok->idx + 1], &tok->str_value); else kputc('.', &tok->str_value); } else if ( tok->idx==-2 ) { int i, end = tok->nuidxs ? tok->nuidxs : line->n_allele - 1; if ( end >= line->n_allele - 1 ) end = line->n_allele - 2; for (i=0; i<=end; i++) if ( i>=tok->nidxs || tok->idxs[i] ) { if ( tok->str_value.l ) kputc(',', &tok->str_value); kputs(line->d.allele[i+1], &tok->str_value); } } else if ( line->n_allele>1 ) { kputs(line->d.allele[1], &tok->str_value); int i; for (i=2; in_allele; i++) { kputc(',', &tok->str_value); kputs(line->d.allele[i], &tok->str_value); } } else if ( line->n_allele==1 ) kputc('.', &tok->str_value); tok->nvalues = tok->str_value.l; } static void filters_set_nmissing(filter_t *flt, bcf1_t *line, token_t *tok) { bcf_unpack(line, BCF_UN_FMT); if ( !line->n_sample ) { tok->nvalues = 1; tok->values[0] = 0; return; } int i,igt = bcf_hdr_id2int(flt->hdr, BCF_DT_ID, "GT"); bcf_fmt_t *fmt = NULL; for (i=0; in_fmt; i++) if ( line->d.fmt[i].id==igt ) { fmt = &line->d.fmt[i]; break; } if ( !fmt ) { tok->nvalues = 0; return; } int j,nmissing = 0; #define BRANCH(type_t, convert, is_vector_end) { \ for (i=0; in_sample; i++) \ { \ uint8_t *ptr = fmt->p + i*fmt->size; \ for (j=0; jn; j++) \ { \ type_t val = convert(&ptr[j * sizeof(type_t)]); \ if ( val==is_vector_end ) break; \ if ( val==bcf_gt_missing ) { nmissing++; break; } \ } \ } \ } switch (fmt->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, bcf_int32_vector_end); break; default: fprintf(stderr,"todo: type %d\n", fmt->type); exit(1); break; } #undef BRANCH tok->nvalues = 1; tok->values[0] = tok->tag[0]=='N' ? nmissing : (double)nmissing / line->n_sample; } static int func_npass(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { if ( nstack==0 ) error("Error parsing the expression\n"); token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) error("The function %s works with FORMAT fields\n", rtok->tag); assert(tok->usmpl); int i, npass = 0; for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; if ( tok->pass_samples[i] ) npass++; } hts_expand(double,1,rtok->mvalues,rtok->values); rtok->nsamples = 0; rtok->nvalues = 1; rtok->values[0] = rtok->tag[0]=='N' ? npass : (line->n_sample ? 1.0*npass/line->n_sample : 0); return 1; } static void filters_set_nalt(filter_t *flt, bcf1_t *line, token_t *tok) { tok->nvalues = 1; tok->values[0] = line->n_allele - 1; } static void filters_set_ac(filter_t *flt, bcf1_t *line, token_t *tok) { hts_expand(int32_t, line->n_allele, flt->mtmpi, flt->tmpi); if ( !bcf_calc_ac(flt->hdr, line, flt->tmpi, BCF_UN_INFO|BCF_UN_FMT) ) { tok->nvalues = 0; return; } int i, an = flt->tmpi[0]; for (i=1; in_allele; i++) an += flt->tmpi[i]; if ( !an ) { tok->nvalues = 0; return; } flt->tmpi[0] = an; // for filters_set_[mac|af|maf] if ( tok->idx>=0 ) { tok->nvalues = 1; tok->values[0] = tok->idx+1n_allele ? flt->tmpi[tok->idx+1] : 0; } else if ( line->n_allele==1 ) // no ALT { tok->nvalues = 1; tok->values[0] = 0; } else { hts_expand(double,line->n_allele,tok->mvalues,tok->values); for (i=1; in_allele; i++) tok->values[i-1] = flt->tmpi[i]; tok->nvalues = line->n_allele - 1; } } static void filters_set_an(filter_t *flt, bcf1_t *line, token_t *tok) { filters_set_ac(flt,line,tok); tok->values[0] = tok->nvalues ? flt->tmpi[0] : 0; tok->nvalues = 1; } static void filters_set_mac(filter_t *flt, bcf1_t *line, token_t *tok) { filters_set_ac(flt,line,tok); if ( !tok->nvalues ) return; int i, an = flt->tmpi[0]; for (i=0; invalues; i++) if ( tok->values[i] > an*0.5 ) tok->values[i] = an - tok->values[i]; } static void filters_set_af(filter_t *flt, bcf1_t *line, token_t *tok) { filters_set_ac(flt,line,tok); if ( !tok->nvalues ) return; int i, an = flt->tmpi[0]; for (i=0; invalues; i++) tok->values[i] /= (double)an; } static void filters_set_maf(filter_t *flt, bcf1_t *line, token_t *tok) { filters_set_ac(flt,line,tok); if ( !tok->nvalues ) return; int i, an = flt->tmpi[0]; for (i=0; invalues; i++) { tok->values[i] /= (double)an; if ( tok->values[i] > 0.5 ) tok->values[i] = 1 - tok->values[i]; } } static int func_max(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; rtok->nvalues = 0; if ( !tok->nvalues ) return 1; double *ptr, val = -HUGE_VAL; int i,j, has_value = 0; if ( tok->nsamples ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; has_value = 1; if ( val < ptr[j] ) val = ptr[j]; } } } else { for (i=0; invalues; i++) { if ( bcf_double_is_missing_or_vector_end(tok->values[i]) ) continue; has_value = 1; if ( val < tok->values[i] ) val = tok->values[i]; } } if ( has_value ) { rtok->values[0] = val; rtok->nvalues = has_value; } return 1; } static int func_smpl_max(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) return func_max(flt,line,rtok,stack,nstack); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nsamples; rtok->nval1 = 1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); int i, j, has_value; double val, *ptr; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; val = -HUGE_VAL; has_value = 0; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; has_value = 1; if ( val < ptr[j] ) val = ptr[j]; } if ( has_value ) rtok->values[i] = val; else bcf_double_set_missing(rtok->values[i]); } return 1; } static int func_min(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; rtok->nvalues = 0; if ( !tok->nvalues ) return 1; double *ptr, val = HUGE_VAL; int i,j, has_value = 0; if ( tok->nsamples ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; has_value = 1; if ( val > ptr[j] ) val = ptr[j]; } } } else { for (i=0; invalues; i++) { if ( bcf_double_is_missing_or_vector_end(tok->values[i]) ) continue; has_value = 1; if ( val > tok->values[i] ) val = tok->values[i]; } } if ( has_value ) { rtok->values[0] = val; rtok->nvalues = has_value; } return 1; } static int func_smpl_min(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) return func_min(flt,line,rtok,stack,nstack); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nsamples; rtok->nval1 = 1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); int i, j, has_value; double val, *ptr; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; val = HUGE_VAL; has_value = 0; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; has_value = 1; if ( val > ptr[j] ) val = ptr[j]; } if ( has_value ) rtok->values[i] = val; else bcf_double_set_missing(rtok->values[i]); } return 1; } static int func_avg(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; rtok->nvalues = 0; if ( !tok->nvalues ) return 1; double *ptr, val = 0; int i,j, n = 0; if ( tok->nsamples ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; val += ptr[j]; n++; } } } else { for (i=0; invalues; i++) if ( !bcf_double_is_missing_or_vector_end(tok->values[i]) ) { val += tok->values[i]; n++; } } if ( n ) { rtok->values[0] = val / n; rtok->nvalues = 1; } return 1; } static int func_smpl_avg(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) return func_avg(flt,line,rtok,stack,nstack); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nsamples; rtok->nval1 = 1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); int i, j, n; double val, *ptr; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; val = 0; n = 0; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( !bcf_double_is_missing_or_vector_end(ptr[j]) ) { val += ptr[j]; n++; } } if ( n ) rtok->values[i] = val / n; else bcf_double_set_missing(rtok->values[i]); } return 1; } static int compare_doubles(const void *lhs, const void *rhs) { double arg1 = *(const double*) lhs; double arg2 = *(const double*) rhs; if (arg1 < arg2) return -1; if (arg1 > arg2) return 1; return 0; } static int func_median(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; rtok->nvalues = 0; if ( !tok->nvalues ) return 1; // sweep through all tok->values and while excluding all missing values reuse the very same array int i,j,k = 0, n = 0; if ( tok->nsamples ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) { k += tok->nval1; continue; } for (j=0; jnval1; k++,j++) { if ( bcf_double_is_missing_or_vector_end(tok->values[k]) ) continue; if ( n < k ) tok->values[n] = tok->values[k]; n++; } } } else { for (i=0; invalues; i++) { if ( bcf_double_is_missing_or_vector_end(tok->values[i]) ) continue; if ( n < i ) tok->values[n] = tok->values[i]; n++; } } if ( !n ) return 1; if ( n==1 ) rtok->values[0] = tok->values[0]; else { qsort(tok->values, n, sizeof(double), compare_doubles); rtok->values[0] = n % 2 ? tok->values[n/2] : (tok->values[n/2-1] + tok->values[n/2]) * 0.5; } rtok->nvalues = 1; return 1; } static int func_smpl_median(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) return func_avg(flt,line,rtok,stack,nstack); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nsamples; rtok->nval1 = 1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); int i, j, n; double *ptr; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; n = 0; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; if ( n < j ) ptr[n] = ptr[j]; n++; } if ( n==0 ) bcf_double_set_missing(rtok->values[i]); else if ( n==1 ) rtok->values[i] = ptr[0]; else { qsort(ptr, n, sizeof(double), compare_doubles); rtok->values[i] = n % 2 ? ptr[n/2] : (ptr[n/2-1] + ptr[n/2]) * 0.5; } } return 1; } static int func_stddev(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; rtok->nvalues = 0; if ( !tok->nvalues ) return 1; // sweep through all tok->values and while excluding all missing values reuse the very same array int i,j,k = 0, n = 0; if ( tok->nsamples ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) { k += tok->nval1; continue; } for (j=0; jnval1; k++,j++) { if ( bcf_double_is_missing_or_vector_end(tok->values[k]) ) continue; if ( n < k ) tok->values[n] = tok->values[k]; n++; } } } else { for (i=0; invalues; i++) { if ( bcf_double_is_missing_or_vector_end(tok->values[i]) ) continue; if ( n < i ) tok->values[n] = tok->values[i]; n++; } } if ( !n ) return 1; if ( n==1 ) rtok->values[0] = 0; else { double sdev = 0, avg = 0; for (i=0; ivalues[i]; avg /= n; for (i=0; ivalues[i] - avg) * (tok->values[i] - avg); rtok->values[0] = sqrt(sdev/n); } rtok->nvalues = 1; return 1; } static int func_smpl_stddev(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) return func_avg(flt,line,rtok,stack,nstack); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nsamples; rtok->nval1 = 1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); int i, j, n; double *ptr; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; n = 0; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; if ( n < j ) ptr[n] = ptr[j]; n++; } if ( n==0 ) bcf_double_set_missing(rtok->values[i]); else if ( n==1 ) rtok->values[i] = 0; else { double sdev = 0, avg = 0; for (j=0; jvalues[i] = sqrt(sdev/n); } } return 1; } static int func_sum(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { rtok->nvalues = 0; token_t *tok = stack[nstack - 1]; if ( !tok->nvalues ) return 1; double *ptr, val = 0; int i,j, n = 0; if ( tok->nsamples ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; val += ptr[j]; n++; } } } else { for (i=0; invalues; i++) if ( !bcf_double_is_missing_or_vector_end(tok->values[i]) ) { val += tok->values[i]; n++; } } if ( n ) { rtok->values[0] = val; rtok->nvalues = 1; } return 1; } static int func_smpl_sum(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( !tok->nsamples ) return func_avg(flt,line,rtok,stack,nstack); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nsamples; rtok->nval1 = 1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); int i, j, has_value; double val, *ptr; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; val = 0; has_value = 0; ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) { if ( bcf_double_is_missing_or_vector_end(ptr[j]) ) continue; has_value = 1; val += ptr[j]; } if ( has_value ) rtok->values[i] = val; else bcf_double_set_missing(rtok->values[i]); } return 1; } static int func_abs(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( tok->is_str ) error("ABS() can be applied only on numeric values\n"); rtok->nsamples = tok->nsamples; rtok->nvalues = tok->nvalues; rtok->nval1 = tok->nval1; hts_expand(double,rtok->nvalues,rtok->mvalues,rtok->values); if ( tok->usmpl ) { if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); } if ( !tok->nvalues ) return 1; hts_expand(double, rtok->nvalues, rtok->mvalues, rtok->values); int i,j,k = 0; if ( tok->usmpl ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) { k+= tok->nval1; continue; } for (j=0; jnval1; k++,j++) { if ( bcf_double_is_missing_or_vector_end(tok->values[k]) ) bcf_double_set_missing(rtok->values[k]); else rtok->values[k] = fabs(tok->values[k]); } } } else { for (i=0; invalues; i++) { if ( tok->usmpl && !tok->usmpl[i] ) continue; if ( bcf_double_is_missing(tok->values[i]) ) bcf_double_set_missing(rtok->values[i]); else if ( !bcf_double_is_vector_end(tok->values[i]) ) rtok->values[i] = fabs(tok->values[i]); } } return 1; } static int func_count(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; int i,j, cnt = 0; if ( tok->tag && tok->nsamples ) { // raw number of values in a FMT tag, e.g. COUNT(FMT/TAG) if ( tok->is_str ) error("todo: Type=String for COUNT on FORMAT fields?\n"); for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) continue; double *ptr = tok->values + i*tok->nval1; for (j=0; jnval1; j++) if ( !bcf_double_is_missing_or_vector_end(ptr[j]) ) cnt++; } } else if ( tok->nsamples ) { // number of samples that pass a processed FMT tag for (i=0; insamples; i++) if ( tok->pass_samples[i] ) cnt++; } else if ( tok->is_str ) { if ( tok->str_value.l ) cnt = 1; for (i=0; istr_value.l; i++) if ( tok->str_value.s[i]==',' ) cnt++; } else cnt = tok->nvalues; rtok->nvalues = 1; rtok->values[0] = cnt; return 1; } static int func_strlen(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; rtok->nvalues = rtok->str_value.l = 0; if ( !tok->str_value.l ) return 1; if ( tok->idx==-2 ) { int i = 0; char *ss = tok->str_value.s; while ( *ss ) { char *se = ss; while ( *se && *se!=',' ) se++; hts_expand(double, i+1, rtok->mvalues, rtok->values); if ( !*se ) rtok->values[i] = strlen(ss); else { *se = 0; rtok->values[i] = strlen(ss); *se = ','; } ss = *se ? se + 1 : se; i++; } rtok->nvalues = i; } else { if ( !tok->str_value.s[1] && tok->str_value.s[0]=='.' ) rtok->values[0] = 0; else rtok->values[0] = strlen(tok->str_value.s); rtok->nvalues = 1; } return 1; } static int func_binom(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { int i, istack = nstack - rtok->nargs; if ( rtok->nargs!=2 && rtok->nargs!=1 ) error("Error: binom() takes one or two arguments\n"); assert( istack>=0 ); // The expected mean is 0.5. Should we support also prob!=0.5? // // double prob = 0.5; // if ( nstack==3 ) // { // // three parameters, the first one must be a scalar: binom(0.25,AD[0],AD[1]) // if ( !stack[istack]->is_constant ) // error("The first argument of binom() must be a numeric constant if three parameters are given\n"); // prob = stack[istack]->threshold; // istack++; // } // else if ( nstack==2 && stack[istack]->is_constant ) // { // // two parameters, the first can be a scalar: binom(0.25,AD) or binom(AD[0],AD[1]) // prob = stack[istack]->threshold; // istack++; // } token_t *tok = stack[istack]; if ( tok->nsamples ) { // working with a FORMAT tag rtok->nval1 = 1; rtok->nvalues = tok->nsamples; rtok->nsamples = tok->nsamples; hts_expand(double, rtok->nvalues, rtok->mvalues, rtok->values); assert(tok->usmpl); if ( !rtok->usmpl ) rtok->usmpl = (uint8_t*) malloc(tok->nsamples); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples); if ( istack+1==nstack ) { // determine the index from the GT field: binom(AD) int ngt = bcf_get_genotypes(flt->hdr, line, &flt->tmpi, &flt->mtmpi); int max_ploidy = ngt/line->n_sample; if ( ngt <= 0 || max_ploidy < 2 ) // GT not present or not diploid, cannot set { for (i=0; insamples; i++) if ( rtok->usmpl[i] ) bcf_double_set_missing(rtok->values[i]); return rtok->nargs; } for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; int32_t *ptr = flt->tmpi + i*max_ploidy; if ( bcf_gt_is_missing(ptr[0]) || bcf_gt_is_missing(ptr[1]) || ptr[1]==bcf_int32_vector_end ) { bcf_double_set_missing(rtok->values[i]); continue; } int idx1 = bcf_gt_allele(ptr[0]); int idx2 = bcf_gt_allele(ptr[1]); if ( idx1>=line->n_allele ) error("Incorrect allele index at %s:%"PRId64", sample %s\n", bcf_seqname(flt->hdr,line),(int64_t) line->pos+1,flt->hdr->samples[i]); if ( idx2>=line->n_allele ) error("Incorrect allele index at %s:%"PRId64", sample %s\n", bcf_seqname(flt->hdr,line),(int64_t) line->pos+1,flt->hdr->samples[i]); double *vals = tok->values + tok->nval1*i; if ( bcf_double_is_missing_or_vector_end(vals[idx1]) || bcf_double_is_missing_or_vector_end(vals[idx2]) ) { bcf_double_set_missing(rtok->values[i]); continue; } rtok->values[i] = calc_binom_two_sided(vals[idx1],vals[idx2],0.5); if ( rtok->values[i] < 0 ) { bcf_double_set_missing(rtok->values[i]); continue; } } } else { // the fields given explicitly: binom(AD[:0],AD[:1]) token_t *tok2 = stack[istack+1]; if ( tok->nval1!=1 || tok2->nval1!=1 ) error("Expected one value per binom() argument, found %d and %d at %s:%"PRId64"\n",tok->nval1,tok2->nval1, bcf_seqname(flt->hdr,line),(int64_t) line->pos+1); for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; double *ptr1 = tok->values + tok->nval1*i; double *ptr2 = tok2->values + tok2->nval1*i; if ( bcf_double_is_missing_or_vector_end(ptr1[0]) || bcf_double_is_missing_or_vector_end(ptr2[0]) ) { bcf_double_set_missing(rtok->values[i]); continue; } rtok->values[i] = calc_binom_two_sided(ptr1[0],ptr2[0],0.5); if ( rtok->values[i] < 0 ) { bcf_double_set_missing(rtok->values[i]); continue; } } } } else { // working with an INFO tag rtok->nvalues = 1; hts_expand(double, rtok->nvalues, rtok->mvalues, rtok->values); double *ptr1 = NULL, *ptr2 = NULL; if ( istack+1==nstack ) { // only one tag, expecting two values: binom(INFO/AD) if ( tok->nvalues==2 ) { ptr1 = &tok->values[0]; ptr2 = &tok->values[1]; } } else { // two tags, expecting one value in each: binom(INFO/AD[0],INFO/AD[1]) token_t *tok2 = stack[istack+1]; if ( tok->nvalues==1 && tok2->nvalues==1 ) { ptr1 = &tok->values[0]; ptr2 = &tok2->values[0]; } } if ( !ptr1 || !ptr2 || bcf_double_is_missing_or_vector_end(ptr1[0]) || bcf_double_is_missing_or_vector_end(ptr2[0]) ) bcf_double_set_missing(rtok->values[0]); else { rtok->values[0] = calc_binom_two_sided(ptr1[0],ptr2[0],0.5); if ( rtok->values[0] < 0 ) bcf_double_set_missing(rtok->values[0]); } } return rtok->nargs; } static int func_phred(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { token_t *tok = stack[nstack - 1]; if ( tok->is_str ) error("PHRED() can be applied only on numeric values\n"); rtok->nsamples = tok->nsamples; rtok->nval1 = tok->nval1; memcpy(rtok->pass_samples, tok->pass_samples, rtok->nsamples*sizeof(*rtok->pass_samples)); assert(tok->usmpl); if ( !rtok->usmpl ) { rtok->usmpl = (uint8_t*) malloc(tok->nsamples*sizeof(*rtok->usmpl)); memcpy(rtok->usmpl, tok->usmpl, tok->nsamples*sizeof(*rtok->usmpl)); } rtok->nvalues = tok->nvalues; if ( !tok->nvalues ) return 1; hts_expand(double, rtok->nvalues, rtok->mvalues, rtok->values); int i,j,k = 0; if ( tok->usmpl ) { for (i=0; insamples; i++) { if ( !tok->usmpl[i] ) { k+= tok->nval1; continue; } for (j=0; jnval1; k++,j++) { if ( bcf_double_is_missing_or_vector_end(tok->values[k]) ) bcf_double_set_missing(rtok->values[k]); else rtok->values[k] = -4.34294481903*log(tok->values[k]); } } } else { for (i=0; invalues; i++) { if ( bcf_double_is_missing_or_vector_end(tok->values[i]) ) bcf_double_set_missing(rtok->values[i]); else rtok->values[i] = -4.34294481903*log(tok->values[i]); } } return 1; } inline static void tok_init_values(token_t *atok, token_t *btok, token_t *rtok) { token_t *tok; if ( (atok->nsamples || btok->nsamples) && (!atok->nsamples || !btok->nsamples) ) tok = atok->nsamples ? atok : btok; else tok = atok->nvalues > btok->nvalues ? atok : btok; rtok->nvalues = tok->nvalues; rtok->nval1 = tok->nval1; hts_expand(double, rtok->nvalues, rtok->mvalues, rtok->values); } inline static void tok_init_samples(token_t *atok, token_t *btok, token_t *rtok) { if ( (atok->nsamples || btok->nsamples) && !rtok->nsamples ) { rtok->nsamples = atok->nsamples ? atok->nsamples : btok->nsamples; rtok->usmpl = (uint8_t*) calloc(rtok->nsamples,1); int i; for (i=0; insamples; i++) rtok->usmpl[i] |= atok->usmpl[i]; for (i=0; insamples; i++) rtok->usmpl[i] |= btok->usmpl[i]; } if (rtok->nsamples) memset(rtok->pass_samples, 0, rtok->nsamples); } #define VECTOR_ARITHMETICS(atok,btok,_rtok,AOP,TYPE) \ { \ token_t *rtok = _rtok; \ int i, has_values = 0; \ if ( atok->nvalues && btok->nvalues ) \ { \ tok_init_values(atok, btok, rtok); \ tok_init_samples(atok, btok, rtok); \ if ( !atok->nsamples && !btok->nsamples ) \ { \ if ( atok->nvalues!=btok->nvalues && atok->nvalues!=1 && btok->nvalues!=1 ) \ error("Cannot run numeric operator in -i/-e filtering on vectors of different lengths: %d vs %d\n",atok->nvalues,btok->nvalues); \ int ir,ia = 0, ib = 0; \ for (ir=0; irnvalues; ir++) \ { \ if ( atok->nvalues > 1 ) ia = ir; \ if ( btok->nvalues > 1 ) ib = ir; \ if ( bcf_double_is_missing_or_vector_end(atok->values[ia]) || bcf_double_is_missing_or_vector_end(btok->values[ib]) ) \ { \ bcf_double_set_missing(rtok->values[ir]); \ continue; \ } \ has_values = 1; \ rtok->values[ir] = TYPE atok->values[ia] AOP TYPE btok->values[ib]; \ } \ } \ else if ( atok->nsamples && btok->nsamples ) \ { \ assert( atok->nsamples==btok->nsamples ); \ if ( atok->nval1!=btok->nval1 && atok->nval1!=1 && btok->nval1!=1 ) \ error("Cannot run numeric operator in -i/-e filtering on vectors of different lengths: %d vs %d\n",atok->nval1,btok->nval1); \ for (i=0; insamples; i++) \ { \ double *rval = rtok->values + i*rtok->nval1; \ double *aval = atok->values + i*atok->nval1; \ double *bval = btok->values + i*btok->nval1; \ int ir,ia = 0, ib = 0; \ for (ir=0; irnval1; ir++) \ { \ if ( atok->nval1 > 1 ) ia = ir; \ if ( btok->nval1 > 1 ) ib = ir; \ if ( bcf_double_is_missing_or_vector_end(aval[ia]) || bcf_double_is_missing_or_vector_end(bval[ib]) ) \ { \ bcf_double_set_missing(rval[ir]); \ continue; \ } \ has_values = 1; \ rval[ir] = TYPE aval[ia] AOP TYPE bval[ib]; \ } \ } \ } \ else if ( atok->nsamples ) \ { \ assert( btok->nvalues==1 ); \ if ( !bcf_double_is_missing_or_vector_end(btok->values[0]) ) \ { \ for (i=0; invalues; i++) \ { \ if ( bcf_double_is_missing_or_vector_end(atok->values[i]) ) \ { \ bcf_double_set_missing(rtok->values[i]); \ continue; \ } \ has_values = 1; \ rtok->values[i] = TYPE atok->values[i] AOP TYPE btok->values[0]; \ } \ } \ } \ else \ { \ assert( atok->nvalues==1 ); \ if ( !bcf_double_is_missing_or_vector_end(atok->values[0]) ) \ { \ for (i=0; invalues; i++) \ { \ if ( bcf_double_is_missing_or_vector_end(btok->values[i]) ) \ { \ bcf_double_set_missing(rtok->values[i]); \ continue; \ } \ has_values = 1; \ rtok->values[i] = TYPE atok->values[0] AOP TYPE btok->values[i]; \ } \ } \ } \ } \ if ( !has_values ) rtok->nvalues = 0; \ } static int vector_logic_or(filter_t *filter, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { if ( nstack < 2 ) error("Error occurred while processing the filter \"%s\"\n", filter->str); token_t *atok = stack[nstack-2]; token_t *btok = stack[nstack-1]; tok_init_samples(atok, btok, rtok); if ( !atok->pass_site && !btok->pass_site ) return 2; rtok->pass_site = 1; if ( !atok->nsamples && !btok->nsamples ) return 2; int i; if ( rtok->tok_type==TOK_OR_VEC ) // ||, select all samples if one is true { if ( (!atok->nsamples && !atok->pass_site) || (!btok->nsamples && !btok->pass_site) ) { // These two conditions are to ensure the following does not set all samples // at sites with QUAL<=30: // QUAL>30 || FMT/GQ>30 token_t *tok = atok->nsamples ? atok : btok; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = tok->pass_samples[i]; } } else { for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = 1; } } return 2; } // |, only select samples which are actually true if ( !atok->nsamples || !btok->nsamples ) { token_t *tok = atok->nsamples ? atok : btok; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = tok->pass_samples[i]; } return 2; } assert( atok->nsamples==btok->nsamples ); for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = atok->pass_samples[i] | btok->pass_samples[i]; } return 2; } static int vector_logic_and(filter_t *filter, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { if ( nstack < 2 ) error("Error occurred while processing the filter \"%s\". (nstack=%d)\n", filter->str,nstack); token_t *atok = stack[nstack-2]; token_t *btok = stack[nstack-1]; tok_init_samples(atok, btok, rtok); if ( !atok->pass_site || !btok->pass_site ) return 2; if ( !atok->nsamples && !btok->nsamples ) { rtok->pass_site = 1; return 2; } int i; if ( !atok->nsamples || !btok->nsamples ) { token_t *tok = atok->nsamples ? atok : btok; for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = tok->pass_samples[i]; } rtok->pass_site = 1; return 2; } assert( atok->nsamples==btok->nsamples ); if ( rtok->tok_type==TOK_AND_VEC ) // &&, can be true in different samples { for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = atok->pass_samples[i] | btok->pass_samples[i]; } rtok->pass_site = 1; } else // &, must be true within one sample { for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; rtok->pass_samples[i] = atok->pass_samples[i] & btok->pass_samples[i]; if ( rtok->pass_samples[i] ) rtok->pass_site = 1; } } return 2; } // A note about comparisons: // When setting value by determining index from the genotype, we face the problem // of how to interpret truncating arrays. Say we have TAG defined as Number=. and // GT:TAG 1/1:0,1,2 0/0:0 // Then when querying we expect the following expression to evaluate for the second // sample as // -i 'TAG[1:1]="."' .. true // -i 'TAG[1:GT]="."' .. false // The problem is that the implementation truncates the number of fields, filling // usually fewer than the original number of per-sample values. This is fixed by // adding an exception that makes the code aware of this: the GT indexing can be // recognised by having tok->idx==-3 #define CMP_VECTORS(atok,btok,_rtok,CMP_OP,missing_logic) \ { \ token_t *rtok = _rtok; \ int i, j, k; \ tok_init_samples(atok, btok, rtok); \ if ( !atok->nsamples && !btok->nsamples ) \ { \ if ( !atok->nvalues && !btok->nvalues ) { rtok->pass_site = missing_logic[2]; } \ else if ( !atok->nvalues || !btok->nvalues ) \ { \ token_t *tok = atok->nvalues ? atok : btok; \ for (j=0; jnvalues; j++) \ { \ if ( bcf_double_is_missing_or_vector_end(tok->values[j]) ) \ { \ if ( missing_logic[2] ) { rtok->pass_site = 1; break; } \ } \ else if ( missing_logic[1] ) { rtok->pass_site = 1; break; } \ } \ } \ else \ { \ for (i=0; invalues; i++) \ { \ int amiss = bcf_double_is_missing_or_vector_end(atok->values[i]) ? 1 : 0; \ for (j=0; jnvalues; j++) \ { \ int nmiss = amiss + (bcf_double_is_missing_or_vector_end(btok->values[j]) ? 1 : 0); \ if ( nmiss ) \ { \ if ( missing_logic[nmiss] ) { rtok->pass_site = 1; i = atok->nvalues; break; } \ } \ else if ( atok->values[i] > 16777216 || btok->values[j] > 16777216 ) /* Ugly, see #871 */ \ { \ if ( atok->values[i] CMP_OP btok->values[j] ) { rtok->pass_site = 1; i = atok->nvalues; break; } \ } \ else if ( (float)atok->values[i] CMP_OP (float)btok->values[j] ) { rtok->pass_site = 1; i = atok->nvalues; break; } \ } \ } \ } \ } \ else \ { \ if ( !atok->nvalues && !btok->nvalues ) \ { \ if ( missing_logic[2] ) \ { \ for (i=0; insamples; i++) \ if ( rtok->usmpl[i] ) { rtok->pass_samples[i] = missing_logic[2]; rtok->pass_site = 1; } \ } \ } \ else if ( !atok->nvalues || !btok->nvalues ) \ { \ token_t *tok = atok->nvalues ? atok : btok; \ if ( !tok->nsamples ) \ { \ int miss = 0; \ for (j=0; jnvalues; j++) \ miss |= bcf_double_is_missing_or_vector_end(tok->values[j]) ? 1 : 0; \ if ( missing_logic[++miss] ) \ { \ for (i=0; insamples; i++) \ if ( rtok->usmpl[i] ) { rtok->pass_samples[i] = missing_logic[miss]; rtok->pass_site = 1; } \ } \ } \ else \ for (i=0; insamples; i++) \ { \ if ( !rtok->usmpl[i] ) continue; \ double *ptr = tok->values + i*tok->nval1; \ int miss = 0; \ for (j=0; jnval1; j++) \ miss |= bcf_double_is_missing_or_vector_end(ptr[j]) ? 1 : 0; \ if ( missing_logic[++miss] ) { rtok->pass_samples[i] = missing_logic[miss]; rtok->pass_site = 1; } \ } \ } \ else if ( atok->nsamples && btok->nsamples ) \ { \ if ( atok->nval1!=btok->nval1 ) error("Incompatible number of per-sample values in comparison: %d vs %d\n",atok->nval1,btok->nval1); \ if ( atok->nsamples!=btok->nsamples ) error("Incompatible number samples in comparison: %d vs %d\n",atok->nsamples,btok->nsamples); \ for (i=0; insamples; i++) \ { \ if ( !atok->usmpl[i] || !btok->usmpl[i] ) { rtok->usmpl[i] = 0; continue; } \ double *aptr = atok->values + i*atok->nval1; \ double *bptr = btok->values + i*btok->nval1; \ for (j=0; jnval1; j++) \ { \ if ( atok->idx==-3 && bcf_double_is_vector_end(aptr[j]) ) break; /* explained above */ \ if ( btok->idx==-3 && bcf_double_is_vector_end(bptr[j]) ) break; /* explained above */ \ int nmiss = bcf_double_is_missing_or_vector_end(aptr[j]) ? 1 : 0; \ if ( nmiss && !missing_logic[0] ) continue; /* any is missing => result is false */ \ nmiss += (bcf_double_is_missing_or_vector_end(bptr[j]) ? 1 : 0); \ if ( nmiss ) \ { \ if ( missing_logic[nmiss] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; break; } \ } \ else if ( aptr[j] > 16777216 || bptr[j] > 16777216 ) /* Ugly, see #871 */ \ { \ if ( aptr[j] CMP_OP bptr[j] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; break; } \ } \ else if ( (float)aptr[j] CMP_OP (float)bptr[j] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; break; } \ } \ } \ } \ else if ( atok->nsamples )\ { \ for (i=0; insamples; i++) \ { \ if ( !rtok->usmpl[i] ) continue; \ double *aptr = atok->values + i*atok->nval1; \ double *bptr = btok->values; \ for (j=0; jnval1; j++) \ { \ if ( atok->idx==-3 && bcf_double_is_vector_end(aptr[j]) ) break; /* explained above */ \ int miss = bcf_double_is_missing_or_vector_end(aptr[j]) ? 1 : 0; \ if ( miss && !missing_logic[0] ) continue; /* any is missing => result is false */ \ for (k=0; knvalues; k++) \ { \ int nmiss = miss + (bcf_double_is_missing_or_vector_end(bptr[k]) ? 1 : 0); \ if ( nmiss ) \ { \ if ( missing_logic[nmiss] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; j = atok->nval1; break; } \ } \ else if ( aptr[j] > 16777216 || bptr[k] > 16777216 ) /* Ugly, see #871 */ \ { \ if ( aptr[j] CMP_OP bptr[k] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; j = atok->nval1; break; } \ } \ else if ( (float)aptr[j] CMP_OP (float)bptr[k] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; j = atok->nval1; break; } \ } \ } \ } \ } \ else /* btok->nsamples */ \ { \ for (i=0; insamples; i++) \ { \ if ( !rtok->usmpl[i] ) continue; \ double *aptr = atok->values; \ double *bptr = btok->values + i*btok->nval1; \ for (j=0; jnval1; j++) \ { \ if ( atok->idx==-3 && bcf_double_is_vector_end(bptr[j]) ) break; /* explained above */ \ int miss = bcf_double_is_missing_or_vector_end(bptr[j]) ? 1 : 0; \ if ( miss && !missing_logic[0] ) continue; /* any is missing => result is false */ \ for (k=0; knvalues; k++) \ { \ int nmiss = miss + (bcf_double_is_missing_or_vector_end(aptr[k]) ? 1 : 0); \ if ( nmiss ) \ { \ if ( missing_logic[nmiss] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; j = btok->nval1; break; } \ } \ else if ( bptr[j] > 16777216 || aptr[k] > 16777216 ) /* Ugly, see #871 */ \ { \ if ( aptr[k] CMP_OP bptr[j] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; j = btok->nval1; break; } \ } \ else if ( (float)aptr[k] CMP_OP (float)bptr[j] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; j = btok->nval1; break; } \ } \ } \ } \ } \ } \ } static int _regex_vector_strings(regex_t *regex, char *str, size_t len, int logic, int *missing_logic) { char *end = str + len; while ( str < end && *str ) { char *mid = str; while ( mid < end && *mid && *mid!=',' ) mid++; int miss = mid - str == 1 && str[0]=='.' ? 1 : 0; if ( miss && missing_logic[miss] ) return 1; char tmp = *mid; *mid = 0; int match = regexec(regex, str, 0,NULL,0) ? 0 : 1; *mid = tmp; if ( logic==TOK_NLIKE ) match = match ? 0 : 1; if ( match ) return 1; if ( !*mid ) break; str = mid + 1; } return 0; } static inline int _has_missing_string(char *beg) { while ( *beg ) { char *end = beg; while ( *end && *end!=',' ) end++; if ( end-beg==1 && beg[0]=='.' ) return 1; if ( !*end ) break; beg = end + 1; } return 0; } // Compare two strings with multiple fields, for example "A,B,.,C"=="X,Y,A". // Returns 1 if any field matches, otherwise returns 0 static inline int _match_vector_strings(char *abeg, size_t alen, char *bstr, size_t blen, int logic, int *missing_logic) { char *aend = abeg + alen; char *bend = bstr + blen; while ( abeg < aend && *abeg ) { char *amid = abeg; while ( amid < aend && *amid && *amid!=',' ) amid++; int miss = amid - abeg == 1 && abeg[0]=='.' ? 1 : 0; char *bbeg = bstr; while ( bbeg < bend && *bbeg ) { char *bmid = bbeg; while ( bmid < bend && *bmid && *bmid!=',' ) bmid++; int nmiss = miss + (bmid - bbeg == 1 && bbeg[0]=='.' ? 1 : 0); if ( nmiss ) { if ( missing_logic[nmiss] ) return 1; } else { int match = amid-abeg==bmid-bbeg && !strncmp(abeg,bbeg,amid-abeg) ? 1 : 0; if ( logic==TOK_NE ) match = match==1 ? 0 : 1; if ( match ) return 1; } if ( !*bmid ) break; bbeg = bmid + 1; } if ( !*amid ) break; abeg = amid + 1; } return 0; } static void cmp_vector_strings(token_t *atok, token_t *btok, token_t *rtok) { tok_init_samples(atok, btok, rtok); int i, logic = rtok->tok_type; // TOK_EQ, TOK_NE, TOK_LIKE, TOK_NLIKE regex_t *regex = atok->regex ? atok->regex : (btok->regex ? btok->regex : NULL); assert( atok->nvalues==atok->str_value.l && btok->nvalues==btok->str_value.l ); assert( !atok->nsamples || !btok->nsamples ); assert( (!regex && (logic==TOK_EQ || logic==TOK_NE)) || (regex && (logic==TOK_LIKE || logic==TOK_NLIKE)) ); int missing_logic[] = {0,0,0}; if ( logic==TOK_EQ || logic==TOK_LIKE ) missing_logic[0] = missing_logic[2] = 1; else if ( logic==TOK_NE || logic==TOK_NLIKE ) missing_logic[0] = missing_logic[1] = 1; if ( !atok->nsamples && !btok->nsamples ) { if ( !atok->nvalues && !btok->nvalues ) { rtok->pass_site = missing_logic[2]; return; } if ( !atok->nvalues || !btok->nvalues ) { int miss = _has_missing_string(atok->nvalues ? atok->str_value.s : btok->str_value.s); if ( missing_logic[miss+1] ) rtok->pass_site = 1; return; } if ( !regex ) rtok->pass_site = _match_vector_strings(atok->str_value.s, atok->str_value.l, btok->str_value.s, btok->str_value.l, logic, missing_logic); else { token_t *tok = atok->regex ? btok : atok; rtok->pass_site = _regex_vector_strings(regex, tok->str_value.s, tok->str_value.l, logic, missing_logic); } return; } // The case of (!atok->nsamples || !btok->nsamples) if ( !atok->nvalues && !btok->nvalues ) { if ( missing_logic[2] ) { for (i=0; insamples; i++) if ( rtok->usmpl[i] ) { rtok->pass_samples[i] = missing_logic[2]; rtok->pass_site = 1; } } return; } if ( !atok->nvalues || !btok->nvalues ) { token_t *tok = atok->nvalues ? atok : btok; if ( !tok->nsamples ) { int miss = _has_missing_string(tok->str_value.s); if ( !missing_logic[miss+1] ) return; for (i=0; insamples; i++) if ( rtok->usmpl[i] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; } } else for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; int miss = _has_missing_string(tok->str_value.s + i*tok->nval1); if ( missing_logic[miss+1] ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; } } return; } // The case of (!atok->nsamples || !btok->nsamples) && (atok->nvalues && btok->nvalues) token_t *xtok = atok->nsamples ? atok : btok; token_t *ytok = atok->nsamples ? btok : atok; assert( regex==ytok->regex ); for (i=0; insamples; i++) { if ( !rtok->usmpl[i] ) continue; int match; if ( regex ) match = _regex_vector_strings(regex, xtok->str_value.s + i*xtok->nval1, xtok->nval1, logic, missing_logic); else match = _match_vector_strings(xtok->str_value.s + i*xtok->nval1, xtok->nval1, ytok->str_value.s, ytok->str_value.l, logic, missing_logic); if ( match ) { rtok->pass_samples[i] = 1; rtok->pass_site = 1; } } } static int parse_idxs(char *tag_idx, int **idxs, int *nidxs, int *idx) { // TAG[], TAG[*] .. any field; sets idx=-2, idxs[0]=-1 if ( *tag_idx==0 || !strcmp("*", tag_idx) ) { *idxs = (int*) malloc(sizeof(int)); (*idxs)[0] = -1; *nidxs = 1; *idx = -2; return 0; } if ( !strcmp("GT", tag_idx) ) { *idxs = (int*) malloc(sizeof(int)); (*idxs)[0] = -1; *nidxs = 1; *idx = -3; return 0; } // TAG[integer] .. one field; idx positive char *end, *beg = tag_idx; *idx = strtol(tag_idx, &end, 10); if ( *idx >= 0 && *end==0 ) return 0; // TAG[0,1] or TAG[0-2] or [1-] etc; idx=-2, idxs[...]=0,0,1,1,.. int i, ibeg = -1; while ( *beg ) { int num = strtol(beg, &end, 10); if ( end[0]==',' ) beg = end + 1; else if ( end[0]==0 ) beg = end; else if ( end[0]=='-' ) { beg = end + 1; ibeg = num; continue; } else return -1; if ( num >= *nidxs ) { *idxs = (int*) realloc(*idxs, sizeof(int)*(num+1)); memset(*idxs + *nidxs, 0, sizeof(int)*(num - *nidxs + 1)); *nidxs = num + 1; } if ( ibeg>=0 ) { for (i=ibeg; i<=num; i++) (*idxs)[i] = 1; ibeg = -1; } (*idxs)[num] = 1; } if ( ibeg >=0 ) { if ( ibeg >= *nidxs ) { *idxs = (int*) realloc(*idxs, sizeof(int)*(ibeg+1)); memset(*idxs + *nidxs, 0, sizeof(int)*(ibeg - *nidxs + 1)); *nidxs = ibeg + 1; } (*idxs)[ibeg] = -1; } *idx = -2; return 0; } static void parse_tag_idx(bcf_hdr_t *hdr, int is_fmt, char *tag, char *tag_idx, token_t *tok) // tag_idx points just after "TAG[" { int i, len = strlen(tag_idx); if ( tag_idx[len-1] == ']' ) tag_idx[len-1] = 0; char *ori = strdup(tag_idx); assert( !tok->idxs && !tok->usmpl ); int *idxs1 = NULL, nidxs1 = 0, idx1 = 0; int *idxs2 = NULL, nidxs2 = 0, idx2 = 0; int set_samples = 0; char *colon = strrchr(tag_idx, ':'); if ( tag_idx[0]=='@' ) // file list with sample names { if ( !is_fmt ) error("Could not parse \"%s\". (Not a FORMAT tag yet a sample list provided.)\n", ori); char *fname = expand_path(tag_idx+1); #ifdef _WIN32 if (fname && strlen(fname) > 2 && fname[1] == ':') // Deal with Windows paths, such as 'C:\..' colon = strrchr(fname+2, ':'); #endif int nsmpl; char **list = hts_readlist(fname, 1, &nsmpl); if ( !list && colon ) { if ( parse_idxs(colon+1, &idxs2, &nidxs2, &idx2) != 0 ) error("Could not parse the index: %s\n", ori); tok->idxs = idxs2; tok->nidxs = nidxs2; tok->idx = idx2; colon = strrchr(fname, ':'); *colon = 0; list = hts_readlist(fname, 1, &nsmpl); } if ( !list ) error("Could not read: %s\n", fname); free(fname); tok->nsamples = bcf_hdr_nsamples(hdr); tok->usmpl = (uint8_t*) calloc(tok->nsamples,1); for (i=0; iusmpl[ismpl] = 1; } free(list); if ( !colon ) { tok->idxs = (int*) malloc(sizeof(int)); tok->idxs[0] = -1; tok->nidxs = 1; tok->idx = -2; } } else if ( colon ) { if ( !is_fmt ) error("Could not parse the index \"%s\". (Not a FORMAT tag yet sample index implied.)\n", ori); *colon = 0; if ( parse_idxs(tag_idx, &idxs1, &nidxs1, &idx1) != 0 ) error("Could not parse the index: %s\n", ori); if ( parse_idxs(colon+1, &idxs2, &nidxs2, &idx2) != 0 ) error("Could not parse the index: %s\n", ori); tok->idxs = idxs2; tok->nidxs = nidxs2; tok->idx = idx2; set_samples = 1; } else { if ( parse_idxs(tag_idx, &idxs1, &nidxs1, &idx1) != 0 ) error("Could not parse the index: %s\n", ori); if ( is_fmt ) { if ( nidxs1==1 && idxs1[0]==-1 ) { tok->idxs = (int*) malloc(sizeof(int)); tok->idxs[0] = -1; tok->nidxs = 1; tok->idx = idx1; } else if ( bcf_hdr_id2number(hdr,BCF_HL_FMT,tok->hdr_id)!=1 ) error("The FORMAT tag %s can have multiple subfields, run as %s[sample:subfield]\n", tag,tag); else tok->idx = 0; set_samples = 1; } else { tok->idxs = idxs1; tok->nidxs = nidxs1; tok->idx = idx1; } } if ( set_samples ) { tok->nsamples = bcf_hdr_nsamples(hdr); tok->usmpl = (uint8_t*) calloc(tok->nsamples,1); if ( idx1>=0 ) { if ( idx1 >= bcf_hdr_nsamples(hdr) ) error("The sample index is too large: %s\n", ori); tok->usmpl[idx1] = 1; } else if ( idx1==-2 || idx1==-3 ) { for (i=0; i= bcf_hdr_nsamples(hdr) ) error("The sample index is too large: %s\n", ori); tok->usmpl[i] = 1; } if ( nidxs1 && idxs1[nidxs1-1]==-1 ) // open range, such as "7-" { for (; insamples; i++) tok->usmpl[i] = 1; } } else error("todo: %s:%d .. %d\n", __FILE__,__LINE__, idx2); free(idxs1); } free(ori); if ( tok->nidxs && tok->idxs[tok->nidxs-1]!=-1 ) { for (i=0; inidxs; i++) if ( tok->idxs[i] ) tok->nuidxs++; } } static int max_ac_an_unpack(bcf_hdr_t *hdr) { int hdr_id = bcf_hdr_id2int(hdr,BCF_DT_ID,"AC"); if ( hdr_id<0 ) return BCF_UN_FMT; if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,hdr_id) ) return BCF_UN_FMT; hdr_id = bcf_hdr_id2int(hdr,BCF_DT_ID,"AN"); if ( hdr_id<0 ) return BCF_UN_FMT; if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,hdr_id) ) return BCF_UN_FMT; return BCF_UN_INFO; } static int filters_init1_ext(filter_t *filter, char *str, int len, token_t *tok) { tok->hl_type = -1; tok->ht_type = -1; tok->tok_type = TOK_VAL; tok->hdr_id = -1; tok->pass_site = -1; tok->idx = 0; tok->iext = ++filter->n_ext; filter->ext = realloc(filter->ext,sizeof(*filter->ext)*filter->n_ext); if ( !strncasecmp(str,"{str}",len) ) { tok->ht_type = BCF_HT_STR; tok->is_str = 1; } else if ( !strncasecmp(str,"{int}",len) ) tok->ht_type = BCF_HT_INT; else if ( !strncasecmp(str,"{float}",len) ) tok->ht_type = BCF_HT_REAL; filter->ext[filter->n_ext-1] = tok->ht_type; return 0; } static int filters_init1(filter_t *filter, char *str, int len, token_t *tok) { tok->ht_type = -1; tok->hl_type = -1; tok->tok_type = TOK_VAL; tok->hdr_id = -1; tok->pass_site = -1; tok->idx = 0; // is this a string constant? if ( str[0]=='"' || str[0]=='\'' ) { int quote = str[0]; if ( str[len-1] != quote ) error("TODO: [%s]\n", filter->str); tok->key = (char*) calloc(len-1,sizeof(char)); hts_expand(double,1,tok->mvalues,tok->values); tok->values[0] = len-2; memcpy(tok->key,str+1,len-2); tok->key[len-2] = 0; tok->is_str = 1; tok->ht_type = BCF_HT_STR; tok->nvalues = len-2; if ( !strcmp(".",tok->key) ) tok->is_missing = 1; return 0; } // is it a file? if ( str[0]=='@' ) { tok->tag = (char*) calloc(len+1,sizeof(char)); memcpy(tok->tag,str,len); tok->tag[len] = 0; char *fname = expand_path(tok->tag+1); int i, n; char **list = hts_readlist(fname, 1, &n); if ( !list ) error("Could not read: %s\n", fname); free(fname); tok->hash = khash_str2int_init(); for (i=0; ihash,list[i]) ) khash_str2int_inc(tok->hash,list[i]); else free(list[i]); } free(list); return 0; } int is_fmt = -1; if ( !strncasecmp(str,"FMT/",4) ) { str += 4; len -= 4; is_fmt = 1; } else if ( !strncasecmp(str,"FORMAT/",7) ) { str += 7; len -= 7; is_fmt = 1; } else { if ( !strncasecmp(str,"INFO/",5) ) { is_fmt = 0; str += 5; len -= 5; } else if ( !strncasecmp(str,"QUAL",len) || !strncmp(str,"%QUAL",len) /* for backward compatibility */ ) { tok->setter = filters_set_qual; tok->tag = strdup("QUAL"); tok->ht_type = BCF_HT_REAL; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"TYPE",len) || !strncmp(str,"%TYPE",len) /* for backward compatibility */ ) { tok->setter = filters_set_type; tok->tag = strdup("TYPE"); tok->ht_type = BCF_HT_STR; return 0; } else if ( !strncasecmp(str,"FILTER",len) || !strncmp(str,"%FILTER",len) /* for backward compatibility */ ) { tok->comparator = filters_cmp_filter; tok->tag = strdup("FILTER"); filter->max_unpack |= BCF_UN_FLT; tok->hl_type = BCF_HL_FLT; tok->ht_type = BCF_HT_STR; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"ID",len) || !strncasecmp(str,"%ID",len) /* for backward compatibility */ ) { tok->comparator = filters_cmp_id; tok->tag = strdup("ID"); tok->ht_type = BCF_HT_STR; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"CHROM",len) ) { tok->setter = &filters_set_chrom; tok->tag = strdup("CHROM"); tok->ht_type = BCF_HT_STR; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"POS",len) ) { tok->setter = &filters_set_pos; tok->tag = strdup("POS"); tok->ht_type = BCF_HT_INT; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"REF",len) ) { tok->setter = &filters_set_ref_string; tok->is_str = 1; tok->tag = strdup("REF"); tok->ht_type = BCF_HT_STR; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"ALT",len) ) { tok->setter = &filters_set_alt_string; tok->is_str = 1; tok->tag = strdup("ALT"); tok->ht_type = BCF_HT_STR; tok->idxs = (int*) malloc(sizeof(int)); tok->idxs[0] = -1; tok->nidxs = 1; tok->idx = -2; filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strncasecmp(str,"N_ALT",len) ) { tok->setter = &filters_set_nalt; tok->tag = strdup("N_ALT"); tok->ht_type = BCF_HT_INT; return 0; } else if ( !strncasecmp(str,"N_SAMPLES",len) ) { tok->tok_type = TOK_VAL; tok->threshold = bcf_hdr_nsamples(filter->hdr); tok->is_constant = 1; tok->ht_type = BCF_HT_INT; return 0; } else if ( !strncasecmp(str,"N_MISSING",len) ) { filter->max_unpack |= BCF_UN_FMT; tok->setter = &filters_set_nmissing; tok->tag = strdup("N_MISSING"); tok->ht_type = BCF_HT_INT; return 0; } else if ( !strncasecmp(str,"F_MISSING",len) ) { filter->max_unpack |= BCF_UN_FMT; tok->setter = &filters_set_nmissing; tok->tag = strdup("F_MISSING"); tok->ht_type = BCF_HT_REAL; return 0; } } // does it have array subscript? int is_array = 0; kstring_t tmp = {0,0,0}; kputsn(str, len, &tmp); if ( tmp.s[tmp.l-1] == ']' ) { int i; for (i=0; ihdr_id = bcf_hdr_id2int(filter->hdr,BCF_DT_ID,tmp.s); if ( is_fmt==-1 ) { if ( tok->hdr_id >=0 ) { int is_info = bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_INFO,tok->hdr_id) ? 1 : 0; is_fmt = bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_FMT,tok->hdr_id) ? 1 : 0; if ( is_info && is_fmt ) error("Error: ambiguous filtering expression, both INFO/%s and FORMAT/%s are defined in the VCF header.\n" , tmp.s,tmp.s); } if ( is_fmt==-1 ) is_fmt = 0; } if ( is_array ) { parse_tag_idx(filter->hdr, is_fmt, tmp.s, tmp.s+is_array, tok); if ( tok->idx==-3 && bcf_hdr_id2length(filter->hdr,BCF_HL_FMT,tok->hdr_id)!=BCF_VL_R ) error("Error: GT subscripts can be used only with Number=R tags\n"); } else if ( is_fmt && !tok->nsamples ) { int i; tok->nsamples = bcf_hdr_nsamples(filter->hdr); tok->usmpl = (uint8_t*) malloc(tok->nsamples); for (i=0; insamples; i++) tok->usmpl[i] = 1; } tok->hl_type = is_fmt ? BCF_HL_FMT : BCF_HL_INFO; if ( is_fmt ) filter->max_unpack |= BCF_UN_FMT; if ( tok->hdr_id>=0 ) { if ( is_fmt && !strcmp("GT",tmp.s) ) { tok->setter = &filters_set_genotype_string; tok->is_str = 1; tok->ht_type = BCF_HT_STR; } else if ( is_fmt ) { if ( !bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_FMT,tok->hdr_id) ) error("No such FORMAT field: %s\n", tmp.s); if ( bcf_hdr_id2number(filter->hdr,BCF_HL_FMT,tok->hdr_id)!=1 && !is_array ) { tok->idxs = (int*) malloc(sizeof(int)); tok->idxs[0] = -1; tok->nidxs = 1; tok->idx = -2; } switch ( bcf_hdr_id2type(filter->hdr,BCF_HL_FMT,tok->hdr_id) ) { case BCF_HT_INT: tok->setter = &filters_set_format_int; tok->ht_type = BCF_HT_INT; break; case BCF_HT_REAL: tok->setter = &filters_set_format_float; tok->ht_type = BCF_HT_REAL; break; case BCF_HT_STR: tok->setter = &filters_set_format_string; tok->ht_type = BCF_HT_STR; tok->is_str = 1; break; default: error("[%s:%d %s] FIXME\n", __FILE__,__LINE__,__FUNCTION__); } } else if ( !bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_INFO,tok->hdr_id) ) error("No such INFO field: %s\n", tmp.s); else { if ( bcf_hdr_id2type(filter->hdr,BCF_HL_INFO,tok->hdr_id) == BCF_HT_FLAG ) { tok->setter = filters_set_info_flag; tok->ht_type = BCF_HT_INT; } else { tok->ht_type = bcf_hdr_id2type(filter->hdr,BCF_HL_INFO,tok->hdr_id); if ( tok->ht_type == BCF_HT_STR ) tok->is_str = 1; if ( bcf_hdr_id2number(filter->hdr,BCF_HL_INFO,tok->hdr_id)==1 ) tok->setter = filters_set_info; else { switch ( bcf_hdr_id2type(filter->hdr,BCF_HL_INFO,tok->hdr_id) ) { case BCF_HT_INT: tok->setter = &filters_set_info_int; break; case BCF_HT_REAL: tok->setter = &filters_set_info_float; break; case BCF_HT_STR: tok->setter = &filters_set_info_string; tok->is_str = 1; break; default: error("[%s:%d %s] FIXME\n", __FILE__,__LINE__,__FUNCTION__); } if (!is_array) { tok->idx = -2; tok->idxs = (int*) malloc(sizeof(int)); tok->idxs[0] = -1; tok->nidxs = 1; } } } filter->max_unpack |= BCF_UN_INFO; } tok->tag = strdup(tmp.s); if ( tmp.s ) free(tmp.s); filter_add_used_tag(filter,is_fmt ? "FORMAT/" : "INFO/",tok->tag); return 0; } else if ( !strcasecmp(tmp.s,"ALT") ) { tok->setter = &filters_set_alt_string; tok->is_str = 1; tok->ht_type = BCF_HT_STR; tok->tag = strdup(tmp.s); free(tmp.s); filter_add_used_tag(filter,NULL,tok->tag); return 0; } else if ( !strcasecmp(tmp.s,"AN") ) { filter->max_unpack |= BCF_UN_FMT; tok->setter = &filters_set_an; tok->tag = strdup("AN"); tok->ht_type = BCF_HT_INT; free(tmp.s); return 0; } else if ( !strcasecmp(tmp.s,"AC") ) { filter->max_unpack |= BCF_UN_FMT; tok->setter = &filters_set_ac; tok->tag = strdup("AC"); tok->ht_type = BCF_HT_INT; free(tmp.s); return 0; } else if ( !strcasecmp(tmp.s,"MAC") ) { filter->max_unpack |= max_ac_an_unpack(filter->hdr); tok->setter = &filters_set_mac; tok->tag = strdup("MAC"); tok->ht_type = BCF_HT_INT; free(tmp.s); return 0; } else if ( !strcasecmp(tmp.s,"AF") ) { filter->max_unpack |= max_ac_an_unpack(filter->hdr); tok->setter = &filters_set_af; tok->tag = strdup("AF"); tok->ht_type = BCF_HT_REAL; free(tmp.s); return 0; } else if ( !strcasecmp(tmp.s,"MAF") ) { filter->max_unpack |= max_ac_an_unpack(filter->hdr); tok->setter = &filters_set_maf; tok->tag = strdup("MAF"); tok->ht_type = BCF_HT_REAL; free(tmp.s); return 0; } else if ( !strcasecmp(tmp.s,"ILEN") || !strcasecmp(tmp.s,"%ILEN") ) { filter->max_unpack |= BCF_UN_STR; tok->setter = &filters_set_ilen; tok->tag = strdup("ILEN"); tok->ht_type = BCF_HT_INT; free(tmp.s); return 0; } // is it a value? Here we parse as integer/float separately and use strtof // rather than strtod, because the more accurate double representation // would invalidate floating point comparisons like QUAL=59.2, obtained via // htslib/vcf parser. // Update: use strtod() and force floats only in comparisons char *end; tok->threshold = strtol(tmp.s, &end, 10); // integer? if ( end - tmp.s != strlen(tmp.s) ) { errno = 0; tok->threshold = strtod(tmp.s, &end); // float? if ( errno!=0 || end!=tmp.s+len ) { if ( filter->exit_on_error ) error("[%s:%d %s] Error: the tag \"%s\" is not defined in the VCF header\n", __FILE__,__LINE__,__FUNCTION__,tmp.s); filter->status |= FILTER_ERR_UNKN_TAGS; filter_add_undef_tag(filter,tmp.s); } tok->ht_type = BCF_HT_REAL; } else tok->ht_type = BCF_HT_INT; tok->is_constant = 1; if ( tmp.s ) free(tmp.s); return 0; } static void filter_debug_print(token_t *toks, token_t **tok_ptrs, int ntoks) { int i; for (i=0; itok_type==TOK_VAL ) { if ( tok->key ) fprintf(stderr,"%s", tok->key); else if ( tok->tag ) fprintf(stderr,"%s", tok->tag); else fprintf(stderr,"%e", tok->threshold); } else fprintf(stderr,"%c", TOKEN_STRING[tok->tok_type]); if ( tok->setter ) fprintf(stderr,"\t[setter %p]", tok->setter); fprintf(stderr,"\n"); } } static void str_to_lower(char *str) { while ( *str ) { *str = tolower(*str); str++; } } static int perl_exec(filter_t *flt, bcf1_t *line, token_t *rtok, token_t **stack, int nstack) { #if ENABLE_PERL_FILTERS PerlInterpreter *perl = flt->perl; if ( !perl ) error("Error: perl expression without a perl script name\n"); dSP; ENTER; SAVETMPS; PUSHMARK(SP); int i,j, istack = nstack - rtok->nargs; for (i=istack+1; iis_str ) XPUSHs(sv_2mortal(newSVpvn(tok->str_value.s,tok->str_value.l))); else if ( tok->nvalues==1 ) XPUSHs(sv_2mortal(newSVnv(tok->values[0]))); else if ( tok->nvalues>1 ) { AV *av = newAV(); for (j=0; jnvalues; j++) av_push(av, newSVnv(tok->values[j])); SV *rv = newRV_inc((SV*)av); XPUSHs(rv); } else { bcf_double_set_missing(tok->values[0]); XPUSHs(sv_2mortal(newSVnv(tok->values[0]))); } } PUTBACK; // A possible future todo: provide a means to select samples and indexes, // expressions like this don't work yet // perl.filter(FMT/AD)[1:0] int nret = call_pv(stack[istack]->str_value.s, G_ARRAY); SPAGAIN; rtok->nvalues = nret; hts_expand(double, rtok->nvalues, rtok->mvalues, rtok->values); for (i=nret; i>0; i--) { rtok->values[i-1] = (double) POPn; if ( isnan(rtok->values[i-1]) ) bcf_double_set_missing(rtok->values[i-1]); } PUTBACK; FREETMPS; LEAVE; #else error("\nPerl filtering requires running `configure --enable-perl-filters` at compile time.\n\n"); #endif return rtok->nargs; } static void perl_init(filter_t *filter, char **str) { char *beg = *str; while ( *beg && isspace(*beg) ) beg++; if ( !*beg ) return; if ( strncasecmp("perl:", beg, 5) ) return; #if ENABLE_PERL_FILTERS beg += 5; char *end = beg; while ( *end && *end!=';' ) end++; // for now not escaping semicolons *str = end+1; if ( ++filter_ninit == 1 ) { // must be executed only once, even for multiple filters; first time here int argc = 0; char **argv = NULL; char **env = NULL; PERL_SYS_INIT3(&argc, &argv, &env); } filter->perl = perl_alloc(); PerlInterpreter *perl = filter->perl; if ( !perl ) error("perl_alloc failed\n"); perl_construct(perl); // name of the perl script to run char *rmme = (char*) calloc(end - beg + 1,1); memcpy(rmme, beg, end - beg); char *argv[] = { "", "" }; argv[1] = expand_path(rmme); free(rmme); PL_origalen = 1; // don't allow $0 change int ret = perl_parse(filter->perl, NULL, 2, argv, NULL); PL_exit_flags |= PERL_EXIT_DESTRUCT_END; if ( ret ) error("Failed to parse: %s\n", argv[1]); free(argv[1]); perl_run(perl); #else error("\nPerl filtering requires running `configure --enable-perl-filters` at compile time.\n\n"); #endif } static void perl_destroy(filter_t *filter) { #if ENABLE_PERL_FILTERS if ( !filter->perl ) return; PerlInterpreter *perl = filter->perl; perl_destruct(perl); perl_free(perl); if ( --filter_ninit <= 0 ) { // similarly to PERL_SYS_INIT3, can must be executed only once? todo: test PERL_SYS_TERM(); } #endif } // A very rudimentary heuristics to determine type, e.g. STR_TAG={} implies {str}. // Throws an error on anything more complex and asks for an explicit type. static void determine_ext_types(filter_t *filter, int ntok, token_t *tok) { int i; for (i=0; istr); for (i=0; iext[j]!=-1 && filter->ext[j]!=tok[i].ht_type ) error("[%s:%d %s] FIXME: this should not happen %d vs %d, iext=%d\n",__FILE__,__LINE__,__FUNCTION__,filter->ext[j],tok[i].ht_type,j); filter->ext[j] = tok[i].ht_type; if ( tok[i].ht_type==BCF_HT_STR ) tok[i].is_str = 1; } } // Parse filter expression and convert to reverse polish notation. Dijkstra's shunting-yard algorithm static filter_t *filter_init_(bcf_hdr_t *hdr, const char *str, int exit_on_error) { filter_t *filter = (filter_t *) calloc(1,sizeof(filter_t)); filter->str = strdup(str); filter->hdr = hdr; filter->max_unpack |= BCF_UN_STR; filter->exit_on_error = exit_on_error; int nops = 0, mops = 0; // operators stack int nout = 0, mout = 0; // filter tokens, RPN token_t *out = NULL; token_t *ops = NULL; char *tmp = filter->str; perl_init(filter, &tmp); int last_op = -1; while ( *tmp ) { int len, ret; ret = filters_next_token(&tmp, &len); if ( ret==-1 ) error("Missing quotes in: %s\n", str); // fprintf(stderr,"token=[%c] .. [%s] %d\n", TOKEN_STRING[ret], tmp, len); // int i; for (i=0; i0 && ops[nops-1].tok_type!=TOK_LFT ) { nout++; hts_expand0(token_t, nout, mout, out); out[nout-1] = ops[nops-1]; memset(&ops[nops-1],0,sizeof(token_t)); nops--; } if ( nops<=0 ) error("Could not parse: %s\n", str); memset(&ops[nops-1],0,sizeof(token_t)); nops--; } else if ( ret==TOK_EXT ) // external value { nout++; hts_expand0(token_t, nout, mout, out); filters_init1_ext(filter, tmp, len, &out[nout-1]); tmp += len; } else if ( ret!=TOK_VAL ) // one of the operators { // detect unary minus: replace -value with -1*(value) if ( ret==TOK_SUB && last_op!=TOK_VAL && last_op!=TOK_RGT ) { nout++; hts_expand0(token_t, nout, mout, out); token_t *tok = &out[nout-1]; tok->tok_type = TOK_VAL; tok->hdr_id = -1; tok->pass_site = -1; tok->threshold = -1.0; tok->is_constant = 1; ret = TOK_MULT; } else if ( ret == -TOK_FUNC ) { // this is different from TOK_PERLSUB,TOK_BINOM in that the expression inside the // brackets gets evaluated as normal expression nops++; hts_expand0(token_t, nops, mops, ops); token_t *tok = &ops[nops-1]; tok->tok_type = -ret; tok->hdr_id = -1; tok->pass_site = -1; tok->threshold = -1.0; if ( !strncasecmp(tmp-len,"N_PASS",6) ) { filter->max_unpack |= BCF_UN_FMT; tok->func = func_npass; tok->tag = strdup("N_PASS"); } else if ( !strncasecmp(tmp-len,"F_PASS",6) ) { filter->max_unpack |= BCF_UN_FMT; tok->func = func_npass; tok->tag = strdup("F_PASS"); } else error("The function \"%s\" is not supported\n", tmp-len); continue; } else if ( ret < 0 ) // variable number of arguments: TOK_PERLSUB,TOK_BINOM { ret = -ret; tmp += len; char *beg = tmp; kstring_t rmme = {0,0,0}; int i, margs, nargs = 0; if ( ret == TOK_PERLSUB ) { while ( *beg && ((isalnum(*beg) && !ispunct(*beg)) || *beg=='_') ) beg++; if ( *beg!='(' ) error("Could not parse the expression: %s\n", str); // the subroutine name kputc('"', &rmme); kputsn(tmp, beg-tmp, &rmme); kputc('"', &rmme); nout++; hts_expand0(token_t, nout, mout, out); filters_init1(filter, rmme.s, rmme.l, &out[nout-1]); nargs++; } char *end = beg; while ( *end && *end!=')' ) end++; if ( !*end ) error("Could not parse the expression: %s\n", str); // subroutine arguments rmme.l = 0; kputsn(beg+1, end-beg-1, &rmme); char **rmme_list = hts_readlist(rmme.s, 0, &margs); for (i=0; itok_type = ret; tok->nargs = nargs; tok->hdr_id = -1; tok->pass_site = -1; tok->threshold = -1.0; tmp = end + 1; continue; } else { while ( nops>0 && op_prec[ret] < op_prec[ops[nops-1].tok_type] ) { nout++; hts_expand0(token_t, nout, mout, out); out[nout-1] = ops[nops-1]; memset(&ops[nops-1],0,sizeof(token_t)); nops--; } } nops++; hts_expand0(token_t, nops, mops, ops); ops[nops-1].tok_type = ret; } else if ( !len ) // all tokes read or an error { if ( *tmp && !isspace(*tmp) ) error("Could not parse the expression: [%s]\n", str); break; // all tokens read } else // TOK_VAL: annotation name or value { nout++; hts_expand0(token_t, nout, mout, out); if ( tmp[len-1]==',' ) filters_init1(filter, tmp, len-1, &out[nout-1]); else filters_init1(filter, tmp, len, &out[nout-1]); tmp += len; } last_op = ret; } while ( nops>0 ) { if ( ops[nops-1].tok_type==TOK_LFT || ops[nops-1].tok_type==TOK_RGT ) error("Could not parse the expression: [%s]\n", filter->str); nout++; hts_expand0(token_t, nout, mout, out); out[nout-1] = ops[nops-1]; memset(&ops[nops-1],0,sizeof(token_t)); nops--; } if ( filter->status != FILTER_OK ) { if ( mops ) free(ops); filter->filters = out; filter->nfilters = nout; return filter; } // Determine types of external variables from the context determine_ext_types(filter,nout,out); // In the special cases of TYPE and FILTER the BCF header IDs are yet unknown. Walk through the // list of operators and convert the strings (e.g. "PASS") to BCF ids. The string value token must be // just before or after the FILTER token and they must be followed with a comparison operator. // At this point we also initialize regex expressions which, in RPN, must precede the LIKE/NLIKE operator. // Additionally, treat "." as missing value rather than a string in numeric equalities; that // @file is only used with ID; etc. // This code is fragile: improve me. static int comma_separator_warned = 0; int i; for (i=0; istr); if ( out[i].hash ) { int j = out[i+1].tok_type==TOK_VAL ? i+1 : i-1; if ( out[j].comparator!=filters_cmp_id ) { if ( out[j].comparator ) error("Error: could not parse the expression with \"@file_name\" syntax (possible todo)\n"); out[j].comparator = filters_cmp_string_hash; } } if ( out[i].tok_type==TOK_OR || out[i].tok_type==TOK_OR_VEC ) out[i].func = vector_logic_or; if ( out[i].tok_type==TOK_AND || out[i].tok_type==TOK_AND_VEC ) out[i].func = vector_logic_and; if ( out[i].tok_type==TOK_EQ || out[i].tok_type==TOK_NE ) { // Look for j="." and k numeric type int j = i-1, k = i-2; if ( !out[j].is_str ) { k = i-1, j = i-2; } if ( out[j].is_str && out[j].key && !strcmp(".",out[j].key) ) { int set_missing = 0; if ( out[k].hdr_id>0 ) { int type = bcf_hdr_id2type(filter->hdr,out[k].hl_type,out[k].hdr_id); if ( type==BCF_HT_INT ) set_missing = 1; else if ( type==BCF_HT_REAL ) set_missing = 1; } else if ( !strcmp("QUAL",out[k].tag) ) set_missing = 1; if ( set_missing ) { out[j].is_str = 0; out[j].is_missing = 1; bcf_double_set_missing(out[j].values[0]); } } } if ( out[i].tok_type==TOK_LIKE || out[i].tok_type==TOK_NLIKE ) { int j = i-1; if ( !out[j].key ) error("Could not parse the expression, wrong value for regex operator: %s\n", filter->str); out[j].regex = (regex_t *) malloc(sizeof(regex_t)); int cflags = REG_NOSUB; int len = strlen(out[j].key); if ( len>2 && out[j].key[len-1]=='i' && out[j].key[len-2]=='/' && out[j].key[len-3]!='\\' ) { out[j].key[len-2] = 0; cflags |= REG_ICASE; } if ( regcomp(out[j].regex, out[j].key, cflags) ) error("Could not compile the regex expression \"%s\": %s\n", out[j].key,filter->str); } if ( out[i].is_str && out[i].tok_type==TOK_VAL && out[i].key && strchr(out[i].key,',') ) { int print_note = 0; if ( out[i+1].tok_type==TOK_EQ || (out[i+1].is_str && out[i+2].tok_type==TOK_EQ) ) print_note = 1; else if ( out[i+1].tok_type==TOK_NE || (out[i+1].is_str && out[i+2].tok_type==TOK_NE) ) print_note = 1; if ( print_note && !comma_separator_warned ) { comma_separator_warned = 1; fprintf(stderr, "Warning: comma is interpreted as a separator and OR logic is used in string comparisons.\n" " (Search the manual for \"Comma in strings\" to learn more.)\n"); } } if ( out[i].tok_type!=TOK_VAL ) continue; if ( !out[i].tag ) continue; if ( out[i].setter==filters_set_type ) { if ( i+1==nout || !out[i+1].key ) error("Could not parse the expression: %s\n", filter->str); int itok, ival; if ( out[i+1].tok_type==TOK_EQ || out[i+1].tok_type==TOK_NE ) ival = i - 1, itok = i + 1; else if ( out[i+1].tok_type==TOK_LIKE || out[i+1].tok_type==TOK_NLIKE ) ival = i - 1, itok = i + 1; else if ( out[i+2].tok_type==TOK_EQ || out[i+2].tok_type==TOK_NE ) itok = i + 2, ival = i + 1; else if ( out[i+2].tok_type==TOK_LIKE || out[i+2].tok_type==TOK_NLIKE ) itok = i + 2, ival = i + 1; else error("[%s:%d %s] Could not parse the expression: %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); if ( !strcasecmp(out[ival].key,"snp") || !strcasecmp(out[ival].key,"snps") ) { out[ival].threshold = VCF_SNP<<1; out[ival].is_str = 0; } else if ( !strcasecmp(out[ival].key,"indel") || !strcasecmp(out[ival].key,"indels") ) { out[ival].threshold = VCF_INDEL<<1; out[ival].is_str = 0; } else if ( !strcasecmp(out[ival].key,"mnp") || !strcasecmp(out[ival].key,"mnps") ) { out[ival].threshold = VCF_MNP<<1; out[ival].is_str = 0; } else if ( !strcasecmp(out[ival].key,"other") ) { out[ival].threshold = VCF_OTHER<<1; out[ival].is_str = 0; } else if ( !strcasecmp(out[ival].key,"bnd") ) { out[ival].threshold = VCF_BND<<1; out[ival].is_str = 0; } else if ( !strcasecmp(out[ival].key,"overlap") ) { out[ival].threshold = VCF_OVERLAP<<1; out[ival].is_str = 0; } else if ( !strcasecmp(out[ival].key,"ref") ) { out[ival].threshold = 1; out[ival].is_str = 0; } else error("The type \"%s\" not recognised: %s\n", out[ival].key, filter->str); out[ival].is_constant = 1; if ( out[itok].tok_type==TOK_LIKE || out[itok].tok_type==TOK_NLIKE ) out[itok].comparator = filters_cmp_bit_and; out[ival].tag = out[ival].key; out[ival].key = NULL; i = itok; continue; } if ( !strcmp(out[i].tag,"GT") ) { if ( i+1==nout ) error("Could not parse the expression: %s\n", filter->str); int ival; if ( out[i+1].tok_type==TOK_EQ || out[i+1].tok_type==TOK_NE ) ival = i - 1; else if ( out[i+1].tok_type==TOK_LIKE || out[i+1].tok_type==TOK_NLIKE ) ival = i - 1; else if ( out[i+2].tok_type==TOK_EQ || out[i+2].tok_type==TOK_NE ) ival = i + 1; else if ( out[i+2].tok_type==TOK_LIKE || out[i+2].tok_type==TOK_NLIKE ) ival = i + 1; else error("[%s:%d %s] Could not parse the expression: %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); if ( !out[ival].key ) error("Comparison between samples is not supported, sorry!\n"); // assign correct setters and unify expressions, eg ar->ra, HOM->hom, etc if ( !strcasecmp(out[ival].key,"hom") ) { out[i].setter = filters_set_genotype3; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"het") ) { out[i].setter = filters_set_genotype3; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"hap") ) { out[i].setter = filters_set_genotype3; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"mis") ) { out[i].setter = filters_set_genotype4; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"ref") ) { out[i].setter = filters_set_genotype4; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"alt") ) { out[i].setter = filters_set_genotype4; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"rr") ) { out[i].setter = filters_set_genotype2; str_to_lower(out[ival].key); } else if ( !strcasecmp(out[ival].key,"ra") || !strcasecmp(out[ival].key,"ar") ) { out[i].setter = filters_set_genotype2; out[ival].key[0]='r'; out[ival].key[1]='a'; } // ra else if ( !strcmp(out[ival].key,"aA") || !strcmp(out[ival].key,"Aa") ) { out[i].setter = filters_set_genotype2; out[ival].key[0]='a'; out[ival].key[1]='A'; } // aA else if ( !strcasecmp(out[ival].key,"aa") ) { out[i].setter = filters_set_genotype2; out[ival].key[0]='a'; out[ival].key[1]='a'; } // aa else if ( !strcasecmp(out[ival].key,"a") ) { out[i].setter = filters_set_genotype2; out[ival].key[0]='a'; out[ival].key[1]=0; } // a else if ( !strcasecmp(out[ival].key,"r") ) { out[i].setter = filters_set_genotype2; out[ival].key[0]='r'; out[ival].key[1]=0; } // r continue; } if ( out[i].hl_type==BCF_HL_FLT ) { if ( i+1==nout ) error("Could not parse the expression: %s\n", filter->str); int itok = i, ival; if ( out[i+1].tok_type==TOK_EQ || out[i+1].tok_type==TOK_NE ) ival = i - 1; else if ( out[i+1].tok_type==TOK_LIKE ) out[i+1].tok_type = TOK_IN, ival = i - 1; else if ( out[i+1].tok_type==TOK_NLIKE ) out[i+1].tok_type = TOK_NOT_IN, ival = i - 1; else if ( out[i+2].tok_type==TOK_EQ || out[i+2].tok_type==TOK_NE ) ival = ++i; else if ( out[i+2].tok_type==TOK_LIKE ) out[i+2].tok_type = TOK_IN, ival = ++i; else if ( out[i+2].tok_type==TOK_NLIKE ) out[i+2].tok_type = TOK_NOT_IN, ival = ++i; else error("[%s:%d %s] Could not parse the expression: %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); if ( out[ival].tok_type!=TOK_VAL || !out[ival].key ) error("[%s:%d %s] Could not parse the expression, an unquoted string value perhaps? %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); token_t *tok = &out[ival]; char *bp = tok->key; tok->nvalues = 0; int has_missing = 0; while ( *bp ) { char tmp, *ep = bp; while ( *ep && *ep!=';' ) ep++; tmp = *ep; *ep = 0; if ( !strcmp(".",bp) ) has_missing = 1; else { tok->nvalues++; hts_expand(double,tok->nvalues,tok->mvalues,tok->values); int id = bcf_hdr_id2int(filter->hdr, BCF_DT_ID, bp); if ( !bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_FLT,id) ) error("The filter \"%s\" not present in the VCF header\n", bp); tok->values[tok->nvalues-1] = id; } *ep = tmp; if ( !tmp ) break; bp = ep + 1; } if ( has_missing && tok->nvalues ) error("The FILTER expression cannot contain missing value AND filters: \"%s\" (%d)\n",tok->key,tok->nvalues); out[ival].tag = tok->key; tok->key = NULL; out[itok].hdr_id = tok->hdr_id; continue; } } filter->nsamples = filter->max_unpack&BCF_UN_FMT ? bcf_hdr_nsamples(filter->hdr) : 0; for (i=0; insamples ) { out[i].pass_samples = (uint8_t*)malloc(filter->nsamples); int j; for (j=0; jnsamples; j++) out[i].pass_samples[j] = 0; } } if (0) filter_debug_print(out, NULL, nout); if ( mops ) free(ops); filter->filters = out; filter->nfilters = nout; filter->flt_stack = (token_t **)malloc(sizeof(token_t*)*nout); return filter; } filter_t *filter_parse(bcf_hdr_t *hdr, const char *str) { return filter_init_(hdr, str, 0); } filter_t *filter_init(bcf_hdr_t *hdr, const char *str) { return filter_init_(hdr, str, 1); } void filter_destroy(filter_t *filter) { perl_destroy(filter); int i; for (i=0; infilters; i++) { if ( filter->filters[i].key ) free(filter->filters[i].key); free(filter->filters[i].str_value.s); free(filter->filters[i].tag); free(filter->filters[i].idxs); free(filter->filters[i].usmpl); free(filter->filters[i].values); free(filter->filters[i].pass_samples); if (filter->filters[i].hash) khash_str2int_destroy_free(filter->filters[i].hash); if (filter->filters[i].regex) { regfree(filter->filters[i].regex); free(filter->filters[i].regex); } } for (i=0; inundef_tag; i++) free(filter->undef_tag[i]); for (i=0; inused_tag; i++) free(filter->used_tag[i]); free(filter->ext); free(filter->undef_tag); free(filter->used_tag); free(filter->cached_GT.buf); free(filter->cached_GT.mask); free(filter->filters); free(filter->flt_stack); free(filter->str); free(filter->tmpi); free(filter->tmpf); free(filter->tmps.s); free(filter); } int filter_test_ext(filter_t *filter, bcf1_t *rec, const uint8_t **samples, const void **ext) { if ( !filter->n_ext ) return filter_test(filter,rec,samples); int i; for (i=0; infilters; i++) { token_t *tok = &filter->filters[i]; if ( !tok->iext ) continue; if ( !ext[tok->iext-1] ) { tok->is_missing = 1; tok->nvalues = 0; if ( filter->ext[tok->iext-1]==BCF_HT_STR ) tok->str_value.l = 0; continue; } tok->is_missing = 0; tok->nvalues = 1; if ( filter->ext[tok->iext-1]==BCF_HT_STR ) { tok->str_value.l = 0; kputs((const char*)ext[tok->iext-1],&tok->str_value); tok->nvalues = tok->str_value.l; } else if ( filter->ext[tok->iext-1]==BCF_HT_INT ) tok->values[0] = *((const int*)ext[tok->iext-1]); else if ( filter->ext[tok->iext-1]==BCF_HT_REAL ) tok->values[0] = *((const float*)ext[tok->iext-1]); } return filter_test(filter,rec,samples); } int filter_test(filter_t *filter, bcf1_t *line, const uint8_t **samples) { if ( filter->status != FILTER_OK ) error("Error: the caller did not check the filter status\n"); bcf_unpack(line, filter->max_unpack); int i, nstack = 0; for (i=0; infilters; i++) { filter->filters[i].pass_site = 0; if ( filter->filters[i].tok_type == TOK_VAL ) { if ( filter->filters[i].setter ) // variable, query the VCF line filter->filters[i].setter(filter, line, &filter->filters[i]); else if ( filter->filters[i].key ) // string constant { filter->filters[i].str_value.l = 0; kputs(filter->filters[i].key, &filter->filters[i].str_value); filter->filters[i].nvalues = filter->filters[i].str_value.l; } else if ( filter->filters[i].is_constant ) // numeric constant { filter->filters[i].values[0] = filter->filters[i].threshold; filter->filters[i].nvalues = 1; } filter->flt_stack[nstack++] = &filter->filters[i]; continue; } else if ( filter->filters[i].func ) { int nargs = filter->filters[i].func(filter, line, &filter->filters[i], filter->flt_stack, nstack); filter->flt_stack[nstack-nargs] = &filter->filters[i]; if ( --nargs > 0 ) nstack -= nargs; continue; } if ( nstack<2 ) error("Error occurred while processing the filter \"%s\" (1:%d)\n", filter->str,nstack); // too few values left on the stack int is_str = filter->flt_stack[nstack-1]->is_str + filter->flt_stack[nstack-2]->is_str; if ( filter->filters[i].tok_type == TOK_ADD ) { VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],+,(double)); filter->flt_stack[nstack-2] = &filter->filters[i]; nstack--; continue; } else if ( filter->filters[i].tok_type == TOK_SUB ) { VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],-,(double)); filter->flt_stack[nstack-2] = &filter->filters[i]; nstack--; continue; } else if ( filter->filters[i].tok_type == TOK_MULT ) { VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],*,(double)); filter->flt_stack[nstack-2] = &filter->filters[i]; nstack--; continue; } else if ( filter->filters[i].tok_type == TOK_DIV ) { VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],/,(double)); filter->flt_stack[nstack-2] = &filter->filters[i]; nstack--; continue; } else if ( filter->filters[i].tok_type == TOK_MODULO ) { VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],%,(int)); filter->flt_stack[nstack-2] = &filter->filters[i]; nstack--; continue; } // ideally, these comparators would become func, but this would require more work in init1() if ( filter->filters[i].comparator ) { filter->filters[i].comparator(filter->flt_stack[nstack-1],filter->flt_stack[nstack-2],&filter->filters[i],line); } else if ( filter->flt_stack[nstack-1]->comparator ) { filter->flt_stack[nstack-1]->comparator(filter->flt_stack[nstack-1],filter->flt_stack[nstack-2],&filter->filters[i],line); } else if ( filter->flt_stack[nstack-2]->comparator ) { filter->flt_stack[nstack-2]->comparator(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],line); } else if ( is_str==2 ) { cmp_vector_strings(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i]); } else { if ( is_str==1 ) error("Error: cannot use arithmetic operators to compare strings and numbers\n"); // Determine what to do with one [1] or both [2] sides missing. The first field [0] gives [1]|[2] int missing_logic[] = {0,0,0}; if ( filter->filters[i].tok_type == TOK_EQ ) { missing_logic[0] = missing_logic[2] = 1; } if ( filter->filters[i].tok_type == TOK_NE ) { missing_logic[0] = missing_logic[1] = 1; } if ( filter->filters[i].tok_type == TOK_EQ ) CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],==,missing_logic) else if ( filter->filters[i].tok_type == TOK_NE ) CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],!=,missing_logic) else if ( filter->filters[i].tok_type == TOK_LE ) CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],<=,missing_logic) else if ( filter->filters[i].tok_type == TOK_LT ) CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],<,missing_logic) else if ( filter->filters[i].tok_type == TOK_BT ) CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],>,missing_logic) else if ( filter->filters[i].tok_type == TOK_BE ) CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],&filter->filters[i],>=,missing_logic) else error("todo: %s:%d .. type=%d\n", __FILE__,__LINE__,filter->filters[i].tok_type); } filter->flt_stack[nstack-2] = &filter->filters[i]; nstack--; } if ( nstack>1 ) error("Error occurred while processing the filter \"%s\" (2:%d)\n", filter->str,nstack); // too few values left on the stack if ( samples ) { *samples = filter->max_unpack&BCF_UN_FMT ? filter->flt_stack[0]->pass_samples : NULL; if ( *samples && !filter->flt_stack[0]->nsamples ) { for (i=0; insamples; i++) filter->flt_stack[0]->pass_samples[i] = filter->flt_stack[0]->pass_site; } } return filter->flt_stack[0]->pass_site; } int filter_max_unpack(filter_t *flt) { return flt->max_unpack; } const int *filter_ext_types(filter_t *filter, int *n_ext) { *n_ext = filter->n_ext; return filter->ext; } const double *filter_get_doubles(filter_t *filter, int *nval, int *nval1) { token_t *tok = filter->flt_stack[0]; if ( tok->nvalues ) { *nval = tok->nvalues; *nval1 = tok->nval1; } else { if ( !tok->values ) error("fixme in filter_get_doubles(): %s\n", filter->str); *nval = 1; *nval1 = 1; tok->values[0] = filter->flt_stack[0]->pass_site; } return tok->values; } void filter_set_samples(filter_t *filter, const uint8_t *samples) { int i,j; for (i=0; infilters; i++) { if ( !filter->filters[i].nsamples ) continue; for (j=0; jfilters[i].nsamples; j++) filter->filters[i].usmpl[j] = samples[j]; } } int filter_status(filter_t *filter) { return filter->status; } bcftools-1.21/filter.h000066400000000000000000000101711467060157400147200ustar00rootroot00000000000000/* filter.h -- filter expressions. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __FILTER_H__ #define __FILTER_H__ #include typedef struct _filter_t filter_t; /** * @hdr: BCF header file * @str: see the bcftools filter command help for description. * See also the extended usage described in filter_test_ext(), * intended for programmatic access * Same as filter_parse() but exits on errors */ filter_t *filter_init(bcf_hdr_t *hdr, const char *str); void filter_destroy(filter_t *filter); /** * filter_test() - test whether the BCF record passes the test * @samples: if not NULL, a pointer to an array with samples statuses is * stored in the location referenced by @samples. The pointer * will be set to NULL if the FORMAT fields were not queried. * Returns 1 if the expression is true and 0 if false. */ int filter_test(filter_t *filter, bcf1_t *rec, const uint8_t **samples); /** * filter_test_ext() - same as filter_test(), but sets some of the terms * on the fly. An expression initialized with, say, * "STR_TAG={} | INT_TAG={} | FLT_TAG={}" takes three * additional pointer arguments which are expected to point to memory * area occupied by the appropriate type, see also filter_ext_types(). * The type determination is not fool-proof, in such case the type can * be given explicitly as eg "TAG={str}". * @ext: array of size 'n_ext' occupied with pointers to the data types * inferred from the expression given at the time of initialization. * The pointers set to NULL will be treated as if missing value "." * was given. * @n_ext: the size of 'ext' array */ int filter_test_ext(filter_t *filter, bcf1_t *rec, const uint8_t **samples, const void **ext); /** * filter_set_samples() - restrict filtering expression to samples. * Call after filter_init(). * @samples: use samples set to 1, ignore samples set 0 */ void filter_set_samples(filter_t *filter, const uint8_t *samples); /** * filter_get_doubles() - return a pointer to values from the last filter_test() evaluation */ const double *filter_get_doubles(filter_t *filter, int *nval, int *nval1); int filter_max_unpack(filter_t *filter); /** * filter_ext_types() - returns the number and BCF_HT_* types of external values * found in the filtering expression */ const int *filter_ext_types(filter_t *filter, int *n_ext); /** * Same as filter_init() but may not exit on some type of errors. The caller * must check if the returned value is not NULL and if the consequent call * of filter_status() returns FILTER_OK before the filter_pass() can be called. */ filter_t *filter_parse(bcf_hdr_t *hdr, const char *str); #define FILTER_OK 0 #define FILTER_ERR_UNKN_TAGS 1 #define FILTER_ERR_OTHER 2 /** * Check if filter_parse() was successful */ int filter_status(filter_t *filter); const char **filter_list_undef_tags(filter_t *filter, int *nundef); const char **filter_list_used_tags(filter_t *filter, int *nused); #endif bcftools-1.21/gff.c000066400000000000000000001257701467060157400142040ustar00rootroot00000000000000/* The MIT License Copyright (c) 2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "regidx.h" #include "gff.h" /* Helper structures, only for initialization ftr_t temporary list of all exons, CDS, UTRs */ KHASH_MAP_INIT_INT(int2tscript, gf_tscript_t*) KHASH_MAP_INIT_INT(int2gene, gf_gene_t*) typedef struct { int type; // GF_CDS, GF_EXON, GF_5UTR, GF_3UTR uint32_t beg; uint32_t end; uint32_t trid; uint32_t strand:2; // STRAND_{REV,FWD,UNK} uint32_t phase:2; // 0, 1, 2, or 3 for unknown uint32_t iseq:28; } ftr_t; /* Mapping from GFF ID string (such as ENST00000450305 or Zm00001d027230_P001) to integer id. To keep the memory requirements low, the original version relied on IDs in the form of a string prefix and a numerical id. However, it turns out that this assumption is not valid for some ensembl GFFs, see for example Zea_mays.AGPv4.36.gff3.gz */ typedef struct { void *str2id; // khash_str2int int nstr, mstr; char **str; // numeric id to string } id_tbl_t; typedef struct { // all exons, CDS, UTRs ftr_t *ftr; int nftr, mftr; // mapping from gene id to gf_gene_t kh_int2gene_t *gid2gene; // mapping from transcript id to tscript, for quick CDS anchoring kh_int2tscript_t *id2tr; // sequences void *seq2int; // str2int hash char **seq; int nseq, mseq; // ignored biotypes void *ignored_biotypes; id_tbl_t gene_ids; // temporary table for mapping between gene id (eg. Zm00001d027245) and a numeric idx // pointers to the current partially processed line char *id, *id_end, *parent, *parent_end, *biotype, *biotype_end, *chr, *chr_end, *name, *name_end, *type, *type_end; } aux_t; struct gff_t_ { const char *fname, *dump_fname; // the main regidx lookups, from chr:beg-end to overlapping features and // index iterator regidx_t *idx_cds, *idx_utr, *idx_exon, *idx_tscript; // temporary structures, deleted after initializtion aux_t init; // mapping between transcript id (eg. Zm00001d027245_T001) and a numeric idx id_tbl_t tscript_ids; int strip_chr_names, verbosity; int force; // force run under various conditions. Currently only to skip out-of-phase transcripts struct { int unknown_chr,unknown_tscript_biotype,unknown_strand,unknown_phase,duplicate_id; int unknown_cds_phase,incomplete_cds,wrong_phase,overlapping_cds; } warned; }; static const char *gf_strings_noncoding[] = { "MT_rRNA", "MT_tRNA", "lincRNA", "miRNA", "misc_RNA", "rRNA", "snRNA", "snoRNA", "processed_transcript", "antisense", "macro_lncRNA", "ribozyme", "sRNA", "scRNA", "scaRNA", "sense_intronic", "sense_overlapping", "pseudogene", "processed_pseudogene", "artifact", "IG_pseudogene", "IG_C_pseudogene", "IG_J_pseudogene", "IG_V_pseudogene", "TR_V_pseudogene", "TR_J_pseudogene", "MT_tRNA_pseudogene", "misc_RNA_pseudogene", "miRNA_pseudogene", "ribozyme", "retained_intron", "retrotransposed", "Trna_pseudogene", "transcribed_processed_pseudogene", "transcribed_unprocessed_pseudogene", "transcribed_unitary_pseudogene", "translated_unprocessed_pseudogene", "translated_processed_pseudogene", "known_ncRNA", "unitary_pseudogene", "unprocessed_pseudogene", "LRG_gene", "3_prime_overlapping_ncRNA", "disrupted_domain", "vaultRNA", "bidirectional_promoter_lncRNA", "ambiguous_orf", "lncRNA" }; static const char *gf_strings_coding[] = { "protein_coding", "polymorphic_pseudogene", "IG_C", "IG_D", "IG_J", "IG_LV", "IG_V", "TR_C", "TR_D", "TR_J", "TR_V", "NMD", "non_stop_decay"}; static const char *gf_strings_special[] = { "CDS", "exon", "3_prime_UTR", "5_prime_UTR" }; int gff_set(gff_t *gff, gff_opt_t key, ...) { va_list args; switch (key) { case dump_fname: va_start(args, key); gff->dump_fname = va_arg(args,char*); va_end(args); return 0; case force_out_of_phase: va_start(args, key); gff->force = va_arg(args,int); va_end(args); return 0; case strip_chr_names: va_start(args, key); gff->strip_chr_names = va_arg(args,int); va_end(args); return 0; case verbosity: va_start(args, key); gff->verbosity = va_arg(args,int); va_end(args); return 0; default: error("The key %d is not supported with gff_set\n",key); } return 0; } void *gff_get(gff_t *gff, gff_opt_t key) { switch (key) { case idx_cds: return gff->idx_cds; case idx_utr: return gff->idx_utr; case idx_exon: return gff->idx_exon; case idx_tscript: return gff->idx_tscript; default: error("The key %d is not supported with gff_get\n",key); } return NULL; } const char *gff_id2string(gff_t *gff, id_type_t type, int id) // currently only transcript ids { return gff->tscript_ids.str[id]; } const char *gf_type2gff_string(int type) { if ( !GF_is_coding(type) ) { if ( type < (1<init; char tmp = chr_end[1]; chr_end[1] = 0; int iseq; if ( khash_str2int_get(aux->seq2int, chr_beg, &iseq)!=0 ) { char *new_chr = strdup(chr_beg); hts_expand(char*, aux->nseq+1, aux->mseq, aux->seq); aux->seq[aux->nseq] = new_chr; iseq = khash_str2int_inc(aux->seq2int, aux->seq[aux->nseq]); aux->nseq++; assert( aux->nseq < 1<<29 ); // see gf_gene_t.iseq and ftr_t.iseq } chr_end[1] = tmp; return iseq; } static inline char *gff_skip(const char *line, char *ss) { while ( *ss && *ss!='\t' ) ss++; if ( !*ss ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); return ss+1; } static inline void gff_parse_chr(gff_t *gff, const char *line, char **chr_beg, char **chr_end) { char *se = (char*) line; while ( *se && *se!='\t' ) se++; if ( !*se ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); if ( gff->strip_chr_names && !strncasecmp("chr",line,3) ) line += 3; *chr_beg = (char*) line; *chr_end = se-1; } static inline char *gff_parse_beg_end(const char *line, char *ss, uint32_t *beg, uint32_t *end) { char *se = ss; *beg = strtol(ss, &se, 10) - 1; if ( ss==se ) error("[%s:%d %s] Could not parse the line:\n\t%s\n\t%s\n",__FILE__,__LINE__,__FUNCTION__,line,ss); ss = se+1; *end = strtol(ss, &se, 10) - 1; if ( ss==se ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); return se+1; } static void gff_id_init(id_tbl_t *tbl) { memset(tbl, 0, sizeof(*tbl)); tbl->str2id = khash_str2int_init(); } static void gff_id_destroy(id_tbl_t *tbl) { khash_str2int_destroy_free(tbl->str2id); free(tbl->str); } static inline int gff_id_register(id_tbl_t *tbl, char *beg, char *end, uint32_t *id_ptr) { char tmp = end[1]; end[1] = 0; int id; if ( khash_str2int_get(tbl->str2id, beg, &id) < 0 ) { id = tbl->nstr++; hts_expand(char*, tbl->nstr, tbl->mstr, tbl->str); tbl->str[id] = strdup(beg); khash_str2int_set(tbl->str2id, tbl->str[id], id); } end[1] = tmp; *id_ptr = id; return 0; } static inline int gff_parse_biotype(char *line) { if ( !line ) return -1; switch (*line) { case 'p': if ( !strncmp(line,"protein_coding",14) ) return GF_PROTEIN_CODING; else if ( !strncmp(line,"pseudogene",10) ) return GF_PSEUDOGENE; else if ( !strncmp(line,"processed_transcript",20) ) return GF_PROCESSED_TRANSCRIPT; else if ( !strncmp(line,"processed_pseudogene",20) ) return GF_PROCESSED_PSEUDOGENE; else if ( !strncmp(line,"polymorphic_pseudogene",22) ) return GF_POLYMORPHIC_PSEUDOGENE; break; case 'a': if ( !strncmp(line,"artifact",8) ) return GF_ARTIFACT; else if ( !strncmp(line,"antisense",9) ) return GF_ANTISENSE; else if ( !strncmp(line,"ambiguous_orf",13) ) return GF_AMBIGUOUS_ORF; break; case 'I': if ( !strncmp(line,"IG_pseudogene",13) ) return GF_IG_PSEUDOGENE; else if ( !strncmp(line,"IG_C_pseudogene",15) ) return GF_IG_C_PSEUDOGENE; else if ( !strncmp(line,"IG_J_pseudogene",15) ) return GF_IG_J_PSEUDOGENE; else if ( !strncmp(line,"IG_V_pseudogene",15) ) return GF_IG_V_PSEUDOGENE; else if ( !strncmp(line,"IG_C",4) ) return GF_IG_C; else if ( !strncmp(line,"IG_D",4) ) return GF_IG_D; else if ( !strncmp(line,"IG_J",4) ) return GF_IG_J; else if ( !strncmp(line,"IG_V",4) ) return GF_IG_V; else if ( !strncmp(line,"IG_LV",5) ) return GF_IG_LV; break; case 'T': if ( !strncmp(line,"TR_V_pseudogene",15) ) return GF_TR_V_PSEUDOGENE; else if ( !strncmp(line,"TR_J_pseudogene",15) ) return GF_TR_J_PSEUDOGENE; else if ( !strncmp(line,"TR_C",4) ) return GF_TR_C; else if ( !strncmp(line,"TR_D",4) ) return GF_TR_D; else if ( !strncmp(line,"TR_J",4) ) return GF_TR_J; else if ( !strncmp(line,"TR_V",4) ) return GF_TR_V; break; case 'M': if ( !strncmp(line,"Mt_tRNA_pseudogene",18) ) return GF_MT_tRNA_PSEUDOGENE; else if ( !strncasecmp(line,"Mt_tRNA",7) ) return GF_MT_tRNA; else if ( !strncasecmp(line,"Mt_rRNA",7) ) return GF_MT_tRNA; else if ( !strncasecmp(line,"MRNA",4) ) return GF_PROTEIN_CODING; break; case 'l': if ( !strncmp(line,"lincRNA",7) ) return GF_lincRNA; if ( !strncmp(line,"lncRNA",7) ) return GF_lncRNA; break; case 'm': if ( !strncmp(line,"macro_lncRNA",12) ) return GF_macro_lncRNA; else if ( !strncmp(line,"misc_RNA_pseudogene",19) ) return GF_misc_RNA_PSEUDOGENE; else if ( !strncmp(line,"miRNA_pseudogene",16) ) return GF_miRNA_PSEUDOGENE; else if ( !strncmp(line,"miRNA",5) ) return GF_miRNA; else if ( !strncmp(line,"misc_RNA",8) ) return GF_MISC_RNA; else if ( !strncasecmp(line,"mRNA",4) ) return GF_PROTEIN_CODING; break; case 'r': if ( !strncmp(line,"rRNA",4) ) return GF_rRNA; else if ( !strncmp(line,"ribozyme",8) ) return GF_RIBOZYME; else if ( !strncmp(line,"retained_intron",15) ) return GF_RETAINED_INTRON; else if ( !strncmp(line,"retrotransposed",15) ) return GF_RETROTRANSPOSED; break; case 's': if ( !strncmp(line,"snRNA",5) ) return GF_snRNA; else if ( !strncmp(line,"sRNA",4) ) return GF_sRNA; else if ( !strncmp(line,"scRNA",5) ) return GF_scRNA; else if ( !strncmp(line,"scaRNA",6) ) return GF_scaRNA; else if ( !strncmp(line,"snoRNA",6) ) return GF_snoRNA; else if ( !strncmp(line,"sense_intronic",14) ) return GF_SENSE_INTRONIC; else if ( !strncmp(line,"sense_overlapping",17) ) return GF_SENSE_OVERLAPPING; break; case 't': if ( !strncmp(line,"tRNA_pseudogene",15) ) return GF_tRNA_PSEUDOGENE; else if ( !strncmp(line,"transcribed_processed_pseudogene",32) ) return GF_TRANSCRIBED_PROCESSED_PSEUDOGENE; else if ( !strncmp(line,"transcribed_unprocessed_pseudogene",34) ) return GF_TRANSCRIBED_UNPROCESSED_PSEUDOGENE; else if ( !strncmp(line,"transcribed_unitary_pseudogene",30) ) return GF_TRANSCRIBED_UNITARY_PSEUDOGENE; else if ( !strncmp(line,"translated_unprocessed_pseudogene",33) ) return GF_TRANSLATED_UNPROCESSED_PSEUDOGENE; else if ( !strncmp(line,"translated_processed_pseudogene",31) ) return GF_TRANSLATED_PROCESSED_PSEUDOGENE; break; case 'n': if ( !strncmp(line,"nonsense_mediated_decay",23) ) return GF_NMD; else if ( !strncmp(line,"non_stop_decay",14) ) return GF_NON_STOP_DECAY; break; case 'N': if ( !strncmp(line,"NMD",3) ) return GF_NMD; break; case 'k': if ( !strncmp(line,"known_ncrna",11) ) return GF_KNOWN_NCRNA; break; case 'u': if ( !strncmp(line,"unitary_pseudogene",18) ) return GF_UNITARY_PSEUDOGENE; else if ( !strncmp(line,"unprocessed_pseudogene",22) ) return GF_UNPROCESSED_PSEUDOGENE; break; case 'L': if ( !strncmp(line,"LRG_gene",8) ) return GF_LRG_GENE; break; case '3': if ( !strncasecmp(line,"3prime_overlapping_ncRNA",24) ) return GF_3PRIME_OVERLAPPING_ncRNA; else if ( !strncasecmp(line,"3_prime_overlapping_ncRNA",25) ) return GF_3PRIME_OVERLAPPING_ncRNA; break; case 'd': if ( !strncmp(line,"disrupted_domain",16) ) return GF_DISRUPTED_DOMAIN; break; case 'v': if ( !strncmp(line,"vaultRNA",8) ) return GF_vaultRNA; break; case 'b': if ( !strncmp(line,"bidirectional_promoter_lncRNA",29) ) return GF_BIDIRECTIONAL_PROMOTER_lncRNA; break; } return 0; } static inline int gff_ignored_biotype(gff_t *gff, char *ss, char *se) { if ( !ss ) return 0; char tmp = se[1]; se[1] = 0; char *key = ss; int n = 0; if ( khash_str2int_get(gff->init.ignored_biotypes, ss, &n)!=0 ) key = strdup(ss); khash_str2int_set(gff->init.ignored_biotypes, key, n+1); se[1] = tmp; return 1; } static gf_gene_t *gene_init(aux_t *aux, uint32_t gene_id) { khint_t k = kh_get(int2gene, aux->gid2gene, (int)gene_id); gf_gene_t *gene = (k == kh_end(aux->gid2gene)) ? NULL : kh_val(aux->gid2gene, k); if ( !gene ) { gene = (gf_gene_t*) calloc(1,sizeof(gf_gene_t)); int ret; k = kh_put(int2gene, aux->gid2gene, (int)gene_id, &ret); kh_val(aux->gid2gene,k) = gene; } return gene; } static void gff_parse_transcript(gff_t *gff, const char *line, ftr_t *ftr) { aux_t *aux = &gff->init; ftr->type = gff_parse_biotype(aux->biotype); if ( ftr->type <= 0 ) { char tmp = aux->type_end[1]; aux->type_end[1] = 0; ftr->type = gff_parse_biotype(aux->type); aux->type_end[1] = tmp; } if ( ftr->type <= 0 ) { if ( !gff_ignored_biotype(gff,aux->biotype,aux->biotype_end) ) { if ( gff->verbosity > 0 ) { if ( !gff->warned.unknown_tscript_biotype || gff->verbosity > 1 ) fprintf(stderr,"Warning: Ignoring transcript with unknown biotype .. %s\n", line); gff->warned.unknown_tscript_biotype++; } } return; } if ( !aux->id ) error("[%s:%d %s] Could not parse the line, neither \"ID=transcript:\" nor \"ID=\" substring is present: %s\n",__FILE__,__LINE__,__FUNCTION__,line); if ( !aux->parent ) error("[%s:%d %s] Could not parse the line, neither \"Parent=gene:\" nor \"Parent=\" substring is present: %s\n",__FILE__,__LINE__,__FUNCTION__,line); uint32_t trid,gene_id; gff_id_register(&gff->tscript_ids, aux->id, aux->id_end, &trid); gff_id_register(&aux->gene_ids, aux->parent, aux->parent_end, &gene_id); gf_tscript_t *tr = (gf_tscript_t*) calloc(1,sizeof(gf_tscript_t)); tr->id = trid; tr->strand = ftr->strand; tr->gene = gene_init(aux, gene_id); tr->type = ftr->type; tr->beg = ftr->beg; tr->end = ftr->end; khint_t k; int ret; k = kh_put(int2tscript, aux->id2tr, (int)trid, &ret); kh_val(aux->id2tr,k) = tr; } // register exon, CDS, UTR static void gff_parse_exon(gff_t *gff, const char *line, ftr_t *ftr) { aux_t *aux = &gff->init; if ( !aux->parent ) error("[%s:%d %s] Could not parse the line, neither \"Parent=transcript:\" nor \"Parent=\" substring found: %s\n",__FILE__,__LINE__,__FUNCTION__,line); // associate with transcript id gff_id_register(&gff->tscript_ids, aux->parent, aux->parent_end, &ftr->trid); if ( ftr->strand==STRAND_UNK && gff->verbosity > 0 ) { if ( !gff->warned.unknown_strand || gff->verbosity > 1 ) fprintf(stderr,"Warning: Ignoring GFF feature with unknown strand .. %s\n",line); gff->warned.unknown_strand++; } if ( ftr->phase==CDS_PHASE_UNKN && gff->verbosity > 0 ) { if ( !gff->warned.unknown_phase|| gff->verbosity > 1 ) fprintf(stderr,"Warning: Ignoring GFF feature with unknown phase .. %s\n",line); gff->warned.unknown_phase++; } ftr->iseq = feature_set_seq(gff, aux->chr,aux->chr_end); } static void gff_parse_gene(gff_t *gff, const char *line, ftr_t *ftr) { aux_t *aux = &gff->init; if ( !aux->id ) return; uint32_t gene_id; gff_id_register(&aux->gene_ids, aux->id, aux->id_end, &gene_id); gf_gene_t *gene = gene_init(aux, gene_id); if ( gene->name ) { if ( !gff->warned.duplicate_id || gff->verbosity > 1 ) fprintf(stderr,"Warning: The GFF contains features with duplicate id .. %s\n",line); gff->warned.duplicate_id++; return; } gene->iseq = feature_set_seq(gff, aux->chr,aux->chr_end); gene->beg = ftr->beg; gene->end = ftr->end; gene->strand = ftr->strand; gene->id = gene_id; if ( aux->name ) { gene->name = (char*) malloc(aux->name_end - aux->name + 2); memcpy(gene->name,aux->name,aux->name_end - aux->name + 1); gene->name[aux->name_end - aux->name + 1] = 0; } else gene->name = strdup(aux->gene_ids.str[gene_id]); // Name= field is not present, use the gene ID instead } // Returns 0 for exons,CDS,UTRs to indicate these need to be pruned later and regidx built on them, // or -1 to indicate the structure needs not be saved (either because of an error or because saved // as transcript or gene.) static int gff_parse_line(gff_t *gff, char *line, ftr_t *ftr) { // - skip empty lines and commented lines // - columns // 1. chr // 2. // 3. CDS, transcript, gene, ... // 4-5. beg,end // 6. // 7. strand // 8. phase // 9. Parent=transcript:ENST(\d+);ID=...;biotype=... etc char *ss = line; if ( !*ss ) return -1; // skip blank lines if ( *ss=='#' ) return -1; // skip comments aux_t *aux = &gff->init; gff_parse_chr(gff, line, &aux->chr, &aux->chr_end); ss = gff_skip(line, aux->chr_end + 2); // 3rd column: is this a CDS, transcript, gene, etc.. The parsing order by frequency in Homo_sapiens.GRCh37.87.gff3 int is_gene_line = 0; ftr->type = 0; aux->type = ss; if ( !strncmp("exon\t",ss,5) ) { ftr->type = GF_EXON; ss += 5; } else if ( !strncmp("CDS\t",ss,4) ) { ftr->type = GF_CDS; ss += 4; } else if ( !strncmp("three_prime_UTR\t",ss,16) ) { ftr->type = GF_UTR3; ss += 16; } else if ( !strncmp("five_prime_UTR\t",ss,15) ) { ftr->type = GF_UTR5; ss += 15; } else if ( !strncmp("biological_region\t",ss,18) ) { return -1; } // skip else if ( !strncmp("gene\t",ss,5) ) { is_gene_line = 1; ss += 5; } else ss = gff_skip(line, ss); aux->type_end = ss - 1; // 4-5th columns: beg,end ss = gff_parse_beg_end(line, ss, &ftr->beg,&ftr->end); // 6th column: skip ss = gff_skip(line, ss); // 7th column: strand ftr->strand = -1; if ( *ss == '+' ) ftr->strand = STRAND_FWD; else if ( *ss == '-' ) ftr->strand = STRAND_REV; else ftr->strand = STRAND_UNK; ss += 2; // 8th column: phase (codon offset) ftr->phase = CDS_PHASE_UNKN; if ( *ss == '0' ) ftr->phase = 0; else if ( *ss == '1' ) ftr->phase = 1; else if ( *ss == '2' ) ftr->phase = 2; else if ( *ss == '.' ) ftr->phase = CDS_PHASE_UNKN; // exons and even CDS in some GFFs do not have phase ss += 2; // 9th column: id, parent, name, biotype aux->name = NULL, aux->id = NULL, aux->parent = NULL, aux->biotype = NULL; while ( *ss ) { char *es = ss; while ( *es && *es!=';' ) es++; if ( !strncmp(ss,"ID=",3) ) { ss += 3; aux->id_end = es - 1; aux->id = ss; if ( !strncmp(ss,"gene:",5) ) { aux->id += 5; is_gene_line = 1; } else if ( !strncmp(ss,"transcript:",11) ) aux->id += 11; } else if ( !strncmp(ss,"Name=",5) ) { aux->name = ss + 5; aux->name_end = es - 1; } else if ( !strncmp(ss,"Parent=",7) ) { ss += 7; aux->parent_end = es - 1; aux->parent = ss; if ( !strncmp(ss,"gene:",5) ) aux->parent += 5; else if ( !strncmp(ss,"transcript:",11) ) aux->parent += 11; } else if ( !strncmp(ss,"biotype=",8) ) { aux->biotype = ss + 8; aux->biotype_end = es - 1; } else if ( !strncmp(ss,"gene_biotype=",13) ) { aux->biotype = ss + 13; aux->biotype_end = es - 1; } if ( !*es ) break; ss = es + 1; } if ( is_gene_line || !aux->parent ) { gff_parse_gene(gff, line, ftr); return -1; } if ( ftr->type ) { gff_parse_exon(gff, line, ftr); return 0; } gff_parse_transcript(gff, line, ftr); return -1; } static int cmp_cds_ptr(const void *a, const void *b) { // comparison function for qsort of transcripts's CDS if ( (*((gf_cds_t**)a))->beg < (*((gf_cds_t**)b))->beg ) return -1; if ( (*((gf_cds_t**)a))->beg > (*((gf_cds_t**)b))->beg ) return 1; return 0; } static inline void chr_beg_end(aux_t *aux, int iseq, char **chr_beg, char **chr_end) { *chr_beg = *chr_end = aux->seq[iseq]; while ( (*chr_end)[1] ) (*chr_end)++; } static gf_tscript_t *tscript_init(aux_t *aux, uint32_t trid) { khint_t k = kh_get(int2tscript, aux->id2tr, (int)trid); gf_tscript_t *tr = (k == kh_end(aux->id2tr)) ? NULL : kh_val(aux->id2tr, k); assert( tr ); return tr; } static void register_cds(gff_t *gff, ftr_t *ftr) { // Make the CDS searchable via idx_cds. Note we do not malloc tr->cds just yet. // ftr is the result of parsing a gff CDS line aux_t *aux = &gff->init; gf_tscript_t *tr = tscript_init(aux, ftr->trid); if ( tr->strand != ftr->strand ) error("Conflicting strand in transcript %"PRIu32" .. %d vs %d\n",ftr->trid,tr->strand,ftr->strand); gf_cds_t *cds = (gf_cds_t*) malloc(sizeof(gf_cds_t)); cds->tr = tr; cds->beg = ftr->beg; cds->len = ftr->end - ftr->beg + 1; cds->icds = 0; // to keep valgrind on mac happy cds->phase = ftr->phase; hts_expand(gf_cds_t*,tr->ncds+1,tr->mcds,tr->cds); tr->cds[tr->ncds++] = cds; } static void register_utr(gff_t *gff, ftr_t *ftr) { aux_t *aux = &gff->init; gf_utr_t *utr = (gf_utr_t*) malloc(sizeof(gf_utr_t)); utr->which = ftr->type==GF_UTR3 ? prime3 : prime5; utr->beg = ftr->beg; utr->end = ftr->end; utr->tr = tscript_init(aux, ftr->trid); char *chr_beg, *chr_end; chr_beg_end(&gff->init, utr->tr->gene->iseq, &chr_beg, &chr_end); regidx_push(gff->idx_utr, chr_beg,chr_end, utr->beg,utr->end, &utr); } static void register_exon(gff_t *gff, ftr_t *ftr) { aux_t *aux = &gff->init; gf_exon_t *exon = (gf_exon_t*) malloc(sizeof(gf_exon_t)); exon->beg = ftr->beg; exon->end = ftr->end; exon->tr = tscript_init(aux, ftr->trid); char *chr_beg, *chr_end; chr_beg_end(&gff->init, exon->tr->gene->iseq, &chr_beg, &chr_end); regidx_push(gff->idx_exon, chr_beg,chr_end, exon->beg - N_SPLICE_REGION_INTRON, exon->end + N_SPLICE_REGION_INTRON, &exon); } static void tscript_init_cds(gff_t *gff) { aux_t *aux = &gff->init; // Sort CDS in all transcripts, set offsets, check their phase, length, create index (idx_cds) khint_t k; for (k=0; kid2tr); k++) { if ( !kh_exist(aux->id2tr, k) ) continue; gf_tscript_t *tr = (gf_tscript_t*) kh_val(aux->id2tr, k); // position-to-tscript lookup char *chr_beg, *chr_end; chr_beg_end(aux, tr->gene->iseq, &chr_beg, &chr_end); regidx_push(gff->idx_tscript, chr_beg, chr_end, tr->beg, tr->end, &tr); if ( !tr->ncds ) continue; // transcript with no CDS // sort CDs qsort(tr->cds, tr->ncds, sizeof(gf_cds_t*), cmp_cds_ptr); // trim non-coding start int i, len = 0; if ( tr->strand==STRAND_FWD ) { if ( tr->cds[0]->phase != CDS_PHASE_UNKN ) { if ( tr->cds[0]->phase ) tr->trim |= TRIM_5PRIME; tr->cds[0]->beg += tr->cds[0]->phase; tr->cds[0]->len -= tr->cds[0]->phase; tr->cds[0]->phase = 0; } // sanity check phase; the phase number in gff tells us how many bases to skip in this // feature to reach the first base of the next codon int tscript_ok = 1; for (i=0; incds; i++) { if ( tr->cds[i]->phase == CDS_PHASE_UNKN ) { if ( gff->verbosity > 0 ) { if ( !gff->warned.unknown_cds_phase || gff->verbosity > 1 ) fprintf(stderr,"Warning: CDS with unknown phase, could not verify reading frame in transcript %s\n",gff->tscript_ids.str[tr->id]); gff->warned.unknown_cds_phase++; } len += tr->cds[i]->len; continue; } int phase = tr->cds[i]->phase ? 3 - tr->cds[i]->phase : 0; if ( phase!=len%3 ) { if ( !gff->force ) error("Error: GFF3 assumption failed for transcript %s, CDS=%"PRIu32": phase!=len%%3 (phase=%d, len=%d). Use the --force option to proceed anyway (at your own risk).\n", gff->tscript_ids.str[tr->id],tr->cds[i]->beg+1,phase,len); if ( gff->verbosity > 0 ) { if ( !gff->warned.wrong_phase || gff->verbosity > 1 ) fprintf(stderr,"Warning: The GFF has inconsistent phase column in transcript %s, skipping. CDS pos=%"PRIu32": phase!=len%%3 (phase=%d, len=%d)\n", gff->tscript_ids.str[tr->id],tr->cds[i]->beg+1,phase,len); gff->warned.wrong_phase++; } tscript_ok = 0; break; } len += tr->cds[i]->len; } if ( !tscript_ok ) continue; // skip this transcript } else if ( tr->strand==STRAND_REV ) { if ( tr->cds[tr->ncds-1]->phase != CDS_PHASE_UNKN ) { // Check that the phase is not bigger than CDS length. Curiously, this can really happen, // see Mus_musculus.GRCm38.85.gff3.gz, transcript:ENSMUST00000163141. // This also fixes phase of 5' incomplete CDS, see test/csq/ENST00000520868/ENST00000520868.gff // todo: the same for the fwd strand i = tr->ncds - 1; int phase = tr->cds[i]->phase; if ( phase ) tr->trim |= TRIM_5PRIME; while ( i>=0 && phase > tr->cds[i]->len ) { phase -= tr->cds[i]->len; tr->cds[i]->phase = 0; tr->cds[i]->len = 0; i--; } if ( gff->verbosity > 0 && tr->cds[i]->phase ) { if ( !gff->warned.incomplete_cds || gff->verbosity > 1 ) fprintf(stderr,"Note: truncated transcript %s with incomplete CDS (this is very common)\n",gff->tscript_ids.str[tr->id]); gff->warned.incomplete_cds++; } tr->cds[i]->len -= tr->cds[i]->phase; tr->cds[i]->phase = 0; } // sanity check phase int tscript_ok = 1; for (i=tr->ncds-1; i>=0; i--) { if ( tr->cds[i]->phase == CDS_PHASE_UNKN ) { if ( gff->verbosity > 0 ) { if ( !gff->warned.unknown_cds_phase || gff->verbosity > 1 ) fprintf(stderr,"Warning: CDS with unknown phase, could not verify reading frame in transcript %s\n",gff->tscript_ids.str[tr->id]); gff->warned.unknown_cds_phase++; } len += tr->cds[i]->len; continue; } int phase = tr->cds[i]->phase ? 3 - tr->cds[i]->phase : 0; if ( phase!=len%3 ) { if ( !gff->force ) error("Error: GFF3 assumption failed for transcript %s, CDS=%"PRIu32": phase!=len%%3 (phase=%d, len=%d). Use the --force option to proceed anyway (at your own risk).\n", gff->tscript_ids.str[tr->id],tr->cds[i]->beg+1,phase,len); if ( gff->verbosity > 0 ) { if ( !gff->warned.wrong_phase || gff->verbosity > 1 ) fprintf(stderr,"Warning: The GFF has inconsistent phase column in transcript %s, skipping. CDS pos=%"PRIu32": phase!=len%%3 (phase=%d, len=%d)\n", gff->tscript_ids.str[tr->id],tr->cds[i]->beg+1,phase,len); gff->warned.wrong_phase++; } tscript_ok = 0; break; } len += tr->cds[i]->len; } if ( !tscript_ok ) continue; // skip this transcript } else continue; // unknown strand // set len. At the same check that CDS within a transcript do not overlap len = 0; for (i=0; incds; i++) { tr->cds[i]->icds = i; len += tr->cds[i]->len; if ( !i ) continue; gf_cds_t *a = tr->cds[i-1]; gf_cds_t *b = tr->cds[i]; if ( a->beg + a->len - 1 >= b->beg ) { if ( gff->verbosity > 0 ) { if ( !gff->warned.overlapping_cds || gff->verbosity > 1 ) fprintf(stderr,"Warning: GFF contains overlapping CDS %s, %"PRIu32"-%"PRIu32" and %"PRIu32"-%"PRIu32" (ribosomal slippage?)\n", gff->tscript_ids.str[tr->id], a->beg+1,a->beg+a->len, b->beg+1,b->beg+b->len); gff->warned.overlapping_cds++; } } } if ( len%3 != 0 ) { // There are 13k transcripts with incomplete 3' CDS. See for example ENST00000524289 // http://sep2015.archive.ensembl.org/Homo_sapiens/Transcript/Sequence_cDNA?db=core;g=ENSG00000155868;r=5:157138846-157159019;t=ENST00000524289 // Also, the incomplete CDS can be too short (1 or 2bp), so it is not enough to trim the last one. if ( gff->verbosity > 0 ) { if ( !gff->warned.incomplete_cds || gff->verbosity > 1 ) fprintf(stderr,"Note: truncated transcript %s with incomplete CDS (this is very common)\n",gff->tscript_ids.str[tr->id]); gff->warned.incomplete_cds++; } tr->trim |= TRIM_3PRIME; if ( tr->strand==STRAND_FWD ) { i = tr->ncds - 1; while ( i>=0 && len%3 ) { int dlen = tr->cds[i]->len >= len%3 ? len%3 : tr->cds[i]->len; tr->cds[i]->len -= dlen; len -= dlen; i--; } } else if ( tr->strand==STRAND_REV ) { i = 0; while ( incds && len%3 ) { int dlen = tr->cds[i]->len >= len%3 ? len%3 : tr->cds[i]->len; tr->cds[i]->len -= dlen; tr->cds[i]->beg += dlen; len -= dlen; i++; } } } // set CDS offsets and insert into regidx len=0; for (i=0; incds; i++) { tr->cds[i]->pos = len; len += tr->cds[i]->len; regidx_push(gff->idx_cds, chr_beg,chr_end, tr->cds[i]->beg,tr->cds[i]->beg+tr->cds[i]->len-1, &tr->cds[i]); } } } static void regidx_free_gf(void *payload) { free(*((gf_cds_t**)payload)); } static void regidx_free_tscript(void *payload) { gf_tscript_t *tr = *((gf_tscript_t**)payload); free(tr->cds); free(tr); } static int gff_dump(gff_t *gff, const char *fname) { BGZF *out = bgzf_open(fname,"wg"); if ( !out ) error("Failed to open %s: %s\n", fname, strerror(errno)); kstring_t str = {0,0,0}; khint_t k; for (k=0; kinit.gid2gene); k++) { if ( !kh_exist(gff->init.gid2gene, k) ) continue; gf_gene_t *gene = (gf_gene_t*) kh_val(gff->init.gid2gene, k); char *gene_id = gff->init.gene_ids.str[gene->id]; str.l = 0; ksprintf(&str,"%s\t.\tgene\t%"PRIu32"\t%"PRIu32"\t.\t%c\t.\tID=%s;Name=%s;used=%d\n",gff->init.seq[gene->iseq],gene->beg+1,gene->end+1,gene->strand==STRAND_FWD?'+':(gene->strand==STRAND_REV?'-':'.'),gene_id,gene->name,gene->used); if ( bgzf_write(out, str.s, str.l) != str.l ) error("Error writing %s: %s\n", fname, strerror(errno)); } regitr_t *itr = regitr_init(gff->idx_tscript); while ( regitr_loop(itr) ) { gf_tscript_t *tr = regitr_payload(itr, gf_tscript_t*); char *gene_id = gff->init.gene_ids.str[tr->gene->id]; const char *type = tr->type==GF_PROTEIN_CODING ? "mRNA" : gf_type2gff_string(tr->type); str.l = 0; ksprintf(&str,"%s\t.\t%s\t%"PRIu32"\t%"PRIu32"\t.\t%c\t.\tID=%s;Parent=%s;biotype=%s;used=%d\n",itr->seq,type,itr->beg+1,itr->end+1,tr->strand==STRAND_FWD?'+':(tr->strand==STRAND_REV?'-':'.'),gff->tscript_ids.str[tr->id],gene_id,gf_type2gff_string(tr->type),tr->used); if ( bgzf_write(out, str.s, str.l) != str.l ) error("Error writing %s: %s\n", fname, strerror(errno)); } regitr_destroy(itr); itr = regitr_init(gff->idx_cds); while ( regitr_loop(itr) ) { gf_cds_t *cds = regitr_payload(itr,gf_cds_t*); gf_tscript_t *tr = cds->tr; str.l = 0; ksprintf(&str,"%s\t.\tCDS\t%"PRIu32"\t%"PRIu32"\t.\t%c\t%c\tParent=%s\n",itr->seq,cds->beg+1,cds->beg+cds->len,tr->strand==STRAND_FWD?'+':(tr->strand==STRAND_REV?'-':'.'),cds->phase==3?'.':cds->phase+(int)'0',gff->tscript_ids.str[tr->id]); if ( bgzf_write(out, str.s, str.l) != str.l ) error("Error writing %s: %s\n", fname, strerror(errno)); } regitr_destroy(itr); itr = regitr_init(gff->idx_utr); while ( regitr_loop(itr) ) { gf_utr_t *utr = regitr_payload(itr,gf_utr_t*); gf_tscript_t *tr = utr->tr; str.l = 0; ksprintf(&str,"%s\t.\t%s_prime_UTR\t%"PRIu32"\t%"PRIu32"\t.\t%c\t.\tParent=%s\n",itr->seq,utr->which==prime3?"three":"five",utr->beg+1,utr->end+1,tr->strand==STRAND_FWD?'+':(tr->strand==STRAND_REV?'-':'.'),gff->tscript_ids.str[tr->id]); if ( bgzf_write(out, str.s, str.l) != str.l ) error("Error writing %s: %s\n", fname, strerror(errno)); } regitr_destroy(itr); itr = regitr_init(gff->idx_exon); while ( regitr_loop(itr) ) { gf_exon_t *exon = regitr_payload(itr,gf_exon_t*); gf_tscript_t *tr = exon->tr; str.l = 0; ksprintf(&str,"%s\t.\texon\t%"PRIu32"\t%"PRIu32"\t.\t%c\t.\tParent=%s\n",itr->seq,exon->beg+1,exon->end+1,tr->strand==STRAND_FWD?'+':(tr->strand==STRAND_REV?'-':'.'),gff->tscript_ids.str[tr->id]); if ( bgzf_write(out, str.s, str.l) != str.l ) error("Error writing %s: %s\n", fname, strerror(errno)); } regitr_destroy(itr); if ( bgzf_close(out)!=0 ) error("Error: close failed .. %s\n", fname); free(str.s); return 0; } int gff_parse(gff_t *gff) { if ( gff->verbosity > 0 ) fprintf(stderr,"Parsing %s ...\n", gff->fname); aux_t *aux = &gff->init; aux->seq2int = khash_str2int_init(); // chrom's numeric id aux->gid2gene = kh_init(int2gene); // gene id to gf_gene_t, for idx_gene aux->id2tr = kh_init(int2tscript); // transcript id to tscript_t gff->idx_tscript = regidx_init(NULL, NULL, regidx_free_tscript, sizeof(gf_tscript_t*), NULL); aux->ignored_biotypes = khash_str2int_init(); gff_id_init(&aux->gene_ids); gff_id_init(&gff->tscript_ids); // parse gff kstring_t str = {0,0,0}; htsFile *fp = hts_open(gff->fname,"r"); if ( !fp ) error("Failed to read %s\n", gff->fname); while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 ) { hts_expand(ftr_t, aux->nftr+1, aux->mftr, aux->ftr); int ret = gff_parse_line(gff, str.s, aux->ftr + aux->nftr); if ( !ret ) aux->nftr++; } free(str.s); if ( hts_close(fp)!=0 ) error("Close failed: %s\n", gff->fname); // process gff information: connect CDS and exons to transcripts gff->idx_cds = regidx_init(NULL, NULL, regidx_free_gf, sizeof(gf_cds_t*), NULL); gff->idx_utr = regidx_init(NULL, NULL, regidx_free_gf, sizeof(gf_utr_t*), NULL); gff->idx_exon = regidx_init(NULL, NULL, regidx_free_gf, sizeof(gf_exon_t*), NULL); int i; for (i=0; inftr; i++) { ftr_t *ftr = &aux->ftr[i]; // check whether to keep this feature: is there a mapping trid -> gene_id -> gene? khint_t k = kh_get(int2tscript, aux->id2tr, (int)ftr->trid); if ( k==kh_end(aux->id2tr) ) continue; // no corresponding transcript registered, must be an unsupported biotype gf_tscript_t *tr = kh_val(aux->id2tr,k); tr->used = 1; tr->gene->used = 1; // populate regidx by category: // ftr->type .. GF_CDS, GF_EXON, GF_UTR3, GF_UTR5 // gene->type .. GF_PROTEIN_CODING, GF_MT_rRNA, GF_IG_C, ... if ( ftr->type==GF_CDS ) register_cds(gff, ftr); else if ( ftr->type==GF_EXON ) register_exon(gff, ftr); else if ( ftr->type==GF_UTR5 ) register_utr(gff, ftr); else if ( ftr->type==GF_UTR3 ) register_utr(gff, ftr); else error("something: %s\t%"PRIu32"\t%"PRIu32"\t%s\t%s\n", aux->seq[ftr->iseq],ftr->beg+1,ftr->end+1,gff->tscript_ids.str[ftr->trid],gf_type2gff_string(ftr->type)); } tscript_init_cds(gff); if ( gff->verbosity > 0 ) { fprintf(stderr,"Indexed %d transcripts, %d exons, %d CDSs, %d UTRs\n", regidx_nregs(gff->idx_tscript), regidx_nregs(gff->idx_exon), regidx_nregs(gff->idx_cds), regidx_nregs(gff->idx_utr)); } if ( gff->verbosity > 0 && khash_str2int_size(aux->ignored_biotypes) ) { khash_t(str2int) *ign = (khash_t(str2int)*)aux->ignored_biotypes; fprintf(stderr,"Ignored the following biotypes:\n"); for (i = kh_begin(ign); i < kh_end(ign); i++) { if ( !kh_exist(ign,i)) continue; const char *biotype = kh_key(ign,i); if ( !strcmp(biotype,"TCE") ) biotype = "TCE (\"To be Experimentally Confirmed\")"; fprintf(stderr,"\t%dx\t.. %s\n", kh_value(ign,i), biotype); } } khash_str2int_destroy_free(aux->ignored_biotypes); // warned about unprinted warnings if ( gff->verbosity > 0 ) { int nwarn = 0; #define INC_NWARN(X) if (gff->warned.X) nwarn += gff->verbosity > 1 ? 0 : gff->warned.X - 1; INC_NWARN(unknown_chr); INC_NWARN(unknown_tscript_biotype); INC_NWARN(unknown_strand); INC_NWARN(unknown_phase); INC_NWARN(duplicate_id); INC_NWARN(unknown_cds_phase); INC_NWARN(incomplete_cds); INC_NWARN(wrong_phase); INC_NWARN(overlapping_cds); if ( nwarn > 0 ) fprintf(stderr,"Warning: %d warnings were suppressed, increase verbosity to see them all\n",nwarn); } if ( gff->dump_fname ) gff_dump(gff, gff->dump_fname); if ( !regidx_nregs(gff->idx_tscript) ) error("Error: No usable transcripts found, likely a failure to parse a non-standard GFF file. Please check if the misc/gff2gff\n" " or misc/gff2gff.py script can fix the problem (both do different things). See also the man page for the description\n" " of the expected format http://samtools.github.io/bcftools/bcftools-man.html#csq\n"); free(aux->seq); free(aux->ftr); khash_str2int_destroy_free(aux->seq2int); // keeping only to destroy the genes at the end: kh_destroy(int2gene,aux->gid2gene); kh_destroy(int2tscript,aux->id2tr); gff_id_destroy(&aux->gene_ids); return 0; } gff_t *gff_init(const char *fname) { gff_t *gff = calloc(sizeof(gff_t),1); gff->fname = fname; return gff; } void gff_destroy(gff_t *gff) { khint_t k; if ( gff->init.gid2gene ) { for (k=0; kinit.gid2gene); k++) { if ( !kh_exist(gff->init.gid2gene, k) ) continue; gf_gene_t *gene = (gf_gene_t*) kh_val(gff->init.gid2gene, k); free(gene->name); free(gene); } kh_destroy(int2gene,gff->init.gid2gene); } regidx_destroy(gff->idx_cds); regidx_destroy(gff->idx_utr); regidx_destroy(gff->idx_exon); regidx_destroy(gff->idx_tscript); gff_id_destroy(&gff->tscript_ids); free(gff); } bcftools-1.21/gff.h000066400000000000000000000311101467060157400141710ustar00rootroot00000000000000/* The MIT License Copyright (c) 2023-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* GFF parsing code refactored from csq.c Things that would be nice to have - dynamic N_REF_PAD - for stop-lost events (also in frameshifts) report the number of truncated aa's - memory could be greatly reduced by indexing gff (but it is quite compact already) - deletions that go beyond transcript boundaries are not checked at sequence level - alloc tscript->ref in hap_finalize, introduce fa_off_beg:16,fa_off_end:16 - see test/csq/ENST00000573314/insertion-overlap.vcf #1476288882 Read about transcript types here http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html https://www.ensembl.org/info/genome/variation/prediction/predicted_data.html https://www.gencodegenes.org/pages/biotypes.html List of supported biotypes antisense IG_C_gene IG_D_gene IG_J_gene IG_LV_gene IG_V_gene lincRNA lncRNA .. generic term for 3prime_overlapping_ncRNA, antisense, bidirectional_promoter_lncRNA, lincRNA, macro_lncRNA, non_coding, processed_transcript, sense_intronic, sense_overlapping macro_lncRNA miRNA misc_RNA Mt_rRNA Mt_tRNA polymorphic_pseudogene processed_transcript protein_coding, mRNA ribozyme rRNA sRNA scRNA scaRNA sense_intronic sense_overlapping snRNA snoRNA TR_C_gene TR_D_gene TR_J_gene TR_V_gene The gff parsing logic We collect features such by combining gff lines A,B,C as follows: A .. gene line with a supported biotype A.ID=~/^gene:/ B .. transcript line referencing A with supported biotype B.ID=~/^transcript:/ && B.Parent=~/^gene:A.ID/ C .. corresponding CDS, exon, and UTR lines: C[3] in {"CDS","exon","three_prime_UTR","five_prime_UTR"} && C.Parent=~/^transcript:B.ID/ For coding biotypes ("protein_coding" or "polymorphic_pseudogene") the complete chain link C -> B -> A is required. For the rest, link B -> A suffices. The supported consequence types, sorted by impact: splice_acceptor_variant .. end region of an intron changed (2bp at the 3' end of an intron) splice_donor_variant .. start region of an intron changed (2bp at the 5' end of an intron) stop_gained .. DNA sequence variant resulting in a stop codon frameshift_variant .. number of inserted/deleted bases not a multiple of three, disrupted translational frame stop_lost .. elongated transcript, stop codon changed start_lost .. the first codon changed inframe_altering .. combination of indels leading to unchanged reading frame and length inframe_insertion .. inserted coding sequence, unchanged reading frame inframe_deletion .. deleted coding sequence, unchanged reading frame missense_variant .. amino acid (aa) change, unchanged length splice_region_variant .. change within 1-3 bases of the exon or 3-8 bases of the intron synonymous_variant .. DNA sequence variant resulting in no amino acid change stop_retained_variant .. different stop codon start_retained_variant .. start codon retained by indel realignment non_coding_variant .. variant in non-coding sequence, such as RNA gene 5_prime_UTR_variant 3_prime_UTR_variant intron_variant .. reported only if none of the above intergenic_variant .. reported only if none of the above The annotation algorithm. The algorithm checks if the variant falls in a region of a supported type. The search is performed in the following order, until a match is found: 1. idx_cds(gf_cds_t) - lookup CDS by position, create haplotypes, call consequences 2. idx_utr(gf_utr_t) - check UTR hits 3. idx_exon(gf_exon_t) - check for splice variants 4. idx_tscript(tscript_t) - check for intronic variants, RNAs, etc. These regidx indexes are created by parsing a gff3 file as follows: 1. create the array "ftr" of all UTR, CDS, exons. This will be processed later and pruned based on transcript types we want to keep. In the same go, create the hash "id2tr" of transcripts to keep (based on biotype) which maps from transcript_id to a transcript. At the same time also build the hash "gid2gene" which maps from gene_id to gf_gene_t pointer. 2. build "idx_cds", "idx_tscript", "idx_utr" and "idx_exon" indexes. Use only features from "ftr" which are present in "id2tr". 3. clean data that won't be needed anymore: ftr, id2tr, gid2gene. Data structures. idx_cds, idx_utr, idx_exon, idx_tscript: as described above, regidx structures for fast lookup of exons/transcripts overlapping a region, the payload is a pointer to tscript.cds */ #ifndef GFF_H__ #define GFF_H__ #include #ifndef __FUNCTION__ # define __FUNCTION__ __func__ #endif // Definition of splice_region, splice_acceptor and splice_donor #define N_SPLICE_DONOR 2 #define N_SPLICE_REGION_EXON 3 #define N_SPLICE_REGION_INTRON 8 #define STRAND_REV 0 #define STRAND_FWD 1 #define STRAND_UNK 2 #define TRIM_NONE 0 #define TRIM_5PRIME 1 #define TRIM_3PRIME 2 // GFF line types #define GFF_UNKN_LINE 0 #define GFF_TSCRIPT_LINE 1 #define GFF_GENE_LINE 2 /* Genomic features, for fast lookup by position to overlapping features */ #define GF_coding_bit 6 #define GF_is_coding(x) ((x) & (1< Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include "gvcf.h" #include "bcftools.h" struct _gvcf_t { int *dp_range, ndp_range; // per-sample DP ranges int prev_range; // 0 if not in a block int32_t *dp, mdp, *pl, mpl, npl; int32_t *tmp, mtmp, *gts, ngts,mgts, nqsum,mqsum; float *qsum; int32_t rid, start, end, min_dp; kstring_t als; bcf1_t *line; }; void gvcf_update_header(gvcf_t *gvcf, bcf_hdr_t *hdr) { bcf_hdr_append(hdr,"##INFO="); bcf_hdr_append(hdr,"##INFO="); } gvcf_t *gvcf_init(const char *dp_ranges) { gvcf_t *gvcf = (gvcf_t*) calloc(1,sizeof(gvcf_t)); gvcf->line = bcf_init(); int n = 1; const char *ss = dp_ranges; while ( *ss ) { if ( *ss==',' ) n++; ss++; } gvcf->ndp_range = n; gvcf->dp_range = (int*) malloc(sizeof(int)*gvcf->ndp_range); n = 0; ss = dp_ranges; while ( *ss ) { char *se = (char*) ss; gvcf->dp_range[n++] = strtol(ss,&se,10); if ( se==ss ) return NULL; if ( *se==',' && se[1] ) { ss = se+1; continue; } else if ( !*se ) break; return NULL; } return gvcf; } void gvcf_destroy(gvcf_t *gvcf) { free(gvcf->dp_range); free(gvcf->dp); free(gvcf->pl); free(gvcf->tmp); free(gvcf->qsum); free(gvcf->gts); free(gvcf->als.s); if ( gvcf->line ) bcf_destroy(gvcf->line); free(gvcf); } bcf1_t *gvcf_write(gvcf_t *gvcf, htsFile *fh, bcf_hdr_t *hdr, bcf1_t *rec, int is_ref) { int i, ret, nsmpl = bcf_hdr_nsamples(hdr); int can_collapse = is_ref ? 1 : 0; int32_t dp_range = 0, min_dp = 0; // No record and nothing to flush? if ( !rec && !gvcf->prev_range ) return NULL; // Flush gVCF block if there are no more records, chr changed, a gap // encountered, or other conditions not met (block broken by a non-ref or DP too low). int needs_flush = can_collapse ? 0 : 1; // Can the record be included in a gVCF block? That is, is this a ref-only site? if ( rec && can_collapse ) { bcf_unpack(rec, BCF_UN_ALL); // per-sample depth ret = bcf_get_format_int32(hdr, rec, "DP", &gvcf->tmp, &gvcf->mtmp); if ( ret==nsmpl ) { min_dp = gvcf->tmp[0]; for (i=1; i gvcf->tmp[i] ) min_dp = gvcf->tmp[i]; for (i=0; indp_range; i++) if ( min_dp < gvcf->dp_range[i] ) break; dp_range = i; if ( !dp_range ) { // leave the record unchanged, DP is too small. Alternatively, return NULL here // to skip these sites needs_flush = 1; can_collapse = 0; } } else needs_flush = 1; // DP field not present } if ( gvcf->prev_range && gvcf->prev_range!=dp_range ) needs_flush = 1; if ( !rec || gvcf->rid!=rec->rid || rec->pos > gvcf->end+1 ) needs_flush = 1; // If prev_range is set, something can be flushed if ( gvcf->prev_range && needs_flush ) { // mpileup can output two records with the same position, SNP and // indel. Make sure the end position does not include the non-variant // SNP position just before the indel. if ( rec && rec->rid==gvcf->rid && rec->pos==gvcf->end ) gvcf->end--; gvcf->end++; // from 0-based to 1-based coordinate bcf_clear1(gvcf->line); gvcf->line->rid = gvcf->rid; gvcf->line->pos = gvcf->start; gvcf->line->rlen = gvcf->end - gvcf->start; bcf_update_alleles_str(hdr, gvcf->line, gvcf->als.s); if ( gvcf->start+1 < gvcf->end ) // create gVCF record only if it spans at least two sites bcf_update_info_int32(hdr, gvcf->line, "END", &gvcf->end, 1); bcf_update_info_int32(hdr, gvcf->line, "MIN_DP", &gvcf->min_dp, 1); if ( gvcf->nqsum>0 ) bcf_update_info_float(hdr, gvcf->line, "QS", gvcf->qsum, gvcf->nqsum); if ( gvcf->ngts ) bcf_update_genotypes(hdr,gvcf->line,gvcf->gts,gvcf->ngts); if ( gvcf->npl>0 ) bcf_update_format_int32(hdr, gvcf->line, "PL", gvcf->pl, gvcf->npl); bcf_update_format_int32(hdr, gvcf->line, "DP", gvcf->dp, nsmpl); if ( bcf_write1(fh, hdr, gvcf->line)!=0 ) error("[%s] Error: failed to write the record\n", __func__); gvcf->prev_range = 0; gvcf->rid = -1; gvcf->npl = 0; gvcf->nqsum = 0; gvcf->ngts = 0; if ( !rec ) return NULL; // just flushing the buffer, this was last record } if ( can_collapse ) { if ( !gvcf->prev_range ) { hts_expand(int32_t,nsmpl,gvcf->mdp,gvcf->dp); memcpy(gvcf->dp,gvcf->tmp,nsmpl*sizeof(int32_t)); // tmp still contains DP from rec gvcf->npl = bcf_get_format_int32(hdr, rec, "PL", &gvcf->pl, &gvcf->mpl); gvcf->nqsum = bcf_get_info_float(hdr,rec,"QS",&gvcf->qsum,&gvcf->mqsum); gvcf->ngts = bcf_get_genotypes(hdr,rec,&gvcf->gts,&gvcf->mgts); gvcf->rid = rec->rid; gvcf->start = rec->pos; gvcf->als.l = 0; kputs(rec->d.allele[0],&gvcf->als); for (i=1; in_allele; i++) { kputc(',',&gvcf->als); kputs(rec->d.allele[i],&gvcf->als); } gvcf->min_dp = min_dp; } else { if ( gvcf->min_dp > min_dp ) gvcf->min_dp = min_dp; for (i=0; idp[i] > gvcf->tmp[i] ) gvcf->dp[i] = gvcf->tmp[i]; ret = bcf_get_format_int32(hdr, rec, "PL", &gvcf->tmp, &gvcf->mtmp); if ( ret>=0 ) { if ( ret!=nsmpl*3 ) error("Unexpected number of PL fields\n"); for (i=0; ipl[3*i+1] > gvcf->tmp[3*i+1] ) { gvcf->pl[3*i+1] = gvcf->tmp[3*i+1]; gvcf->pl[3*i+2] = gvcf->tmp[3*i+2]; } else if ( gvcf->pl[3*i+1]==gvcf->tmp[3*i+1] && gvcf->pl[3*i+2] > gvcf->tmp[3*i+2] ) gvcf->pl[3*i+2] = gvcf->tmp[3*i+2]; } } else gvcf->npl = 0; } gvcf->prev_range = dp_range; if ( bcf_get_info_int32(hdr,rec,"END",&gvcf->tmp,&gvcf->mtmp)==1 ) gvcf->end = gvcf->tmp[0] - 1; // from 1-based to 0-based else gvcf->end = rec->pos; return NULL; } if ( is_ref && min_dp ) bcf_update_info_int32(hdr, rec, "MIN_DP", &min_dp, 1); return rec; } bcftools-1.21/gvcf.h000066400000000000000000000030311467060157400143550ustar00rootroot00000000000000/* gvcf.[ch] - Helper functions for gVCF support The MIT License Copyright (c) 2015 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __GVCF_H__ #define __GVCF_H__ #include "bcftools.h" typedef struct _gvcf_t gvcf_t; gvcf_t *gvcf_init(const char *dp_ranges); void gvcf_update_header(gvcf_t *gvcf, bcf_hdr_t *hdr); bcf1_t *gvcf_write(gvcf_t *gvcf, htsFile *fh, bcf_hdr_t *hdr, bcf1_t *rec, int is_ref); void gvcf_destroy(gvcf_t *gvcf); #endif bcftools-1.21/hclust.c000066400000000000000000000307271467060157400147410ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include "bcftools.h" #include "hclust.h" typedef struct _node_t { struct _node_t *akid, *bkid, *next, *prev, *parent; int id, idx; // id: unique node id; idx: current index to pdist float value; // max pairwise dist of elements within the node } node_t; struct _hclust_t { int ndat, nclust; // ndat: number of elements (pdist matrix size); nclust: current number of clusters float *pdist; // pairwise cluster distances, diagonal matrix accessed via the PDIST macro node_t *first, *last; // clusters are maintained in a double-linked list node_t **rmme; // convenience array to remove all allocated nodes at the end int nrmme; kstring_t str; // (for debugging) pointer to str.s is returned by create_dot() char **dbg; // (for debugging) created by create_list() via set_threshold() and returned by explain() int ndbg, mdbg; }; node_t *append_node(hclust_t *clust, int idx) { node_t *node = (node_t*) calloc(1,sizeof(node_t)); clust->nclust++; node->id = clust->nrmme; node->idx = idx; if ( !clust->first ) { clust->first = node; clust->last = node; } else { node->prev = clust->last; clust->last->next = node; clust->last = node; } if ( clust->nrmme >= clust->ndat*2 ) error("hclust fixme: %d vs %d\n",clust->nrmme,clust->ndat); clust->rmme[clust->nrmme++] = node; return node; } void remove_node(hclust_t *clust, node_t *node) { if ( node==clust->first ) clust->first = node->next; if ( node==clust->last ) clust->last = node->prev; if ( node->next ) node->next->prev = node->prev; if ( node->prev ) node->prev->next = node->next; clust->nclust--; } #if DEBUG void hclust_debug(hclust_t *clust) { int i; fprintf(stderr,"nrmme=%d nclust=%d\n", clust->nrmme,clust->nclust); for (i=0; inrmme; i++) { node_t *node = clust->rmme[i]; int akid = node->akid ? node->akid->id : -1; int bkid = node->bkid ? node->bkid->id : -1; int akidx = node->akid ? node->akid->idx : -1; int bkidx = node->bkid ? node->bkid->idx : -1; fprintf(stderr,"\t%d\t%d\t%f\t%d %d\t%d %d\n",node->id,node->idx,node->value,akid,bkid,akidx,bkidx); } int j; for (i=1; indat; i++) { int active = 0; node_t *node = clust->first; while (node) { if ( node->idx==i ) { active=1; break; } node = node->next; } fprintf(stderr,"%2d%c ",i,active?'*':' '); for (j=0; jpdist,i,j)==9 ) fprintf(stderr," ----- "); else fprintf(stderr," %f", PDIST(clust->pdist,i,j)); } fprintf(stderr,"\n"); } for (j=0; jndat-1; j++) fprintf(stderr," %6d ",j); fprintf(stderr,"\n"); } #endif hclust_t *hclust_init(int n, float *pdist) { hclust_t *clust = (hclust_t*) calloc(1,sizeof(hclust_t)); clust->ndat = n; clust->pdist = pdist; clust->rmme = (node_t**) calloc(n*2,sizeof(node_t*)); // init clusters int i; for (i=0; indat; i++) append_node(clust,i); // build the tree while ( clust->nclust>1 ) { // find two clusters with minimum distance float min_value = HUGE_VAL; node_t *iclust = clust->first->next; node_t *min_iclust = NULL, *min_jclust = NULL; while ( iclust ) { node_t *jclust = clust->first; while ( jclust!=iclust ) { float value = PDIST(clust->pdist,iclust->idx,jclust->idx); if ( value < min_value ) { min_value = value; min_iclust = iclust; min_jclust = jclust; } jclust = jclust->next; } iclust = iclust->next; } assert( min_iclust && min_jclust ); // pdist contains inf or nan, fix the caller remove_node(clust,min_iclust); remove_node(clust,min_jclust); // update the pairwise distances. We keep the matrix and as we are moving up the // tree, we use fewer columns/rows as the number of clusters decreases: we reuse // i-th and leave j-th unused. Inter-cluster distance is defined as maximum distance // between pairwise distances of elements within the cluster. iclust = clust->first; while ( iclust ) { if ( PDIST(clust->pdist,iclust->idx,min_iclust->idx) < PDIST(clust->pdist,iclust->idx,min_jclust->idx) ) PDIST(clust->pdist,iclust->idx,min_iclust->idx) = PDIST(clust->pdist,iclust->idx,min_jclust->idx); iclust = iclust->next; } node_t *node = append_node(clust,min_iclust->idx); node->akid = min_iclust; node->bkid = min_jclust; node->value = min_value; node->akid->parent = node; node->bkid->parent = node; } return clust; } void hclust_destroy(hclust_t *clust) { int i; for (i=0; inrmme; i++) free(clust->rmme[i]); free(clust->rmme); free(clust->dbg); free(clust->str.s); free(clust); } char *hclust_create_dot(hclust_t *clust, char **labels, float th) { clust->str.l = 0; ksprintf(&clust->str,"digraph myGraph {"); int i; for (i=0; inrmme; i++) { node_t *node = clust->rmme[i]; if ( node->value ) ksprintf(&clust->str,"\"%d\" [label=\"%f\"];", node->id,node->value); else ksprintf(&clust->str,"\"%d\" [label=\"%s\"];", node->id,labels[node->idx]); } for (i=0; inrmme; i++) { node_t *node = clust->rmme[i]; if ( node->akid ) { if ( node->value >= th && node->akid && node->akid->value < th ) ksprintf(&clust->str,"\"%d\" -> \"%d\" [color=\"#D43F3A\" penwidth=3];", node->id,node->akid->id); else ksprintf(&clust->str,"\"%d\" -> \"%d\";", node->id,node->akid->id); } if ( node->bkid ) { if ( node->value >= th && node->bkid && node->bkid->value < th ) ksprintf(&clust->str,"\"%d\" -> \"%d\" [color=\"#D43F3A\" penwidth=3];", node->id,node->bkid->id); else ksprintf(&clust->str,"\"%d\" -> \"%d\";", node->id,node->bkid->id); } } ksprintf(&clust->str,"};"); return clust->str.s; } char **hclust_explain(hclust_t *clust, int *nlines) { clust->ndbg = 0; char *beg = clust->str.s; while ( *beg ) { char *end = beg; while ( *end && *end!='\n' ) end++; clust->ndbg++; hts_expand(char*,clust->ndbg,clust->mdbg,clust->dbg); clust->dbg[clust->ndbg-1] = beg; if ( !*end ) break; *end = 0; beg = end + 1; } *nlines = clust->ndbg; return clust->dbg; } cluster_t *append_cluster(node_t *node, cluster_t *cluster, int *nclust, node_t **stack) { (*nclust)++; cluster = (cluster_t*) realloc(cluster,sizeof(cluster_t)*(*nclust)); cluster_t *clust = &cluster[*nclust-1]; clust->nmemb = 0; clust->memb = NULL; clust->dist = node->value; int nstack = 1; stack[0] = node; while ( nstack ) { node_t *node = stack[--nstack]; node_t *akid = node->akid; node_t *bkid = node->bkid; if ( node->akid ) { stack[nstack++] = akid; stack[nstack++] = bkid; } else { clust->nmemb++; clust->memb = (int*) realloc(clust->memb,sizeof(int)*clust->nmemb); clust->memb[clust->nmemb-1] = node->id; } } return cluster; } int cmp_nodes(const void *a, const void *b) { const node_t *an = *((const node_t**) a); const node_t *bn = *((const node_t**) b); if ( an->value < bn->value ) return -1; if ( an->value > bn->value ) return 1; return 0; } float calc_dev(node_t **dat, int n) { float avg = 0, dev = 0; int i; for (i=0; ivalue; avg /= n; for (i=0; ivalue - avg)*(dat[i]->value - avg); return sqrt(dev/n); } /* Heuristics to determine clustering cutoff: sort nodes by distance and split into two groups by minimizing the standard deviation. This works best when two elements from a single different sample are included in the mix. - min_inter_dist .. smaller values are always considered identical - max_intra_dist .. larger values are always considered different */ float hclust_set_threshold(hclust_t *clust, float min_inter_dist, float max_intra_dist) { node_t **dat = clust->rmme + clust->ndat; int i, ndat = clust->nrmme - clust->ndat; qsort(dat, ndat, sizeof(dat), cmp_nodes); clust->str.l = 0; float th, min_dev = HUGE_VAL; int imin = -1; for (i=0; i0 ) dev += calc_dev(dat,i); if ( i+1value; ksprintf(&clust->str,"DEV\t%f\t%f\n",th,dev); if ( min_dev > dev && th >= min_inter_dist ) { min_dev = dev; imin = i; } } if ( max_intra_dist > 0 ) th = max_intra_dist; // use fixed cutoff, the above was only for debugging output else { // dynamic cutoff max_intra_dist = fabs(max_intra_dist); th = imin==-1 ? max_intra_dist : dat[imin]->value; if ( th > max_intra_dist ) th = max_intra_dist; } ksprintf(&clust->str,"TH\t%f\n", th); ksprintf(&clust->str,"MAX_DIST\t%f\n", dat[ndat-1]->value); ksprintf(&clust->str,"MIN_INTER\t%f\n", min_inter_dist); ksprintf(&clust->str,"MAX_INTRA\t%f\n", max_intra_dist); return th; } cluster_t *hclust_create_list(hclust_t *clust, float min_inter_dist, float *max_intra_dist, int *nclust) { float cutoff = *max_intra_dist = hclust_set_threshold(clust, min_inter_dist, *max_intra_dist); node_t **stack = (node_t**) malloc(sizeof(node_t*)*clust->ndat); node_t **tmp = (node_t**) malloc(sizeof(node_t*)*clust->ndat); stack[0] = clust->first; int nstack = 1; cluster_t *cluster = NULL; int ncluster = 0; if ( stack[0]->value < cutoff ) { // all values are within the limits - create a single cluster cluster = append_cluster(stack[0], cluster, &ncluster, tmp); nstack = 0; } while ( nstack ) { node_t *node = stack[--nstack]; node_t *akid = node->akid; node_t *bkid = node->bkid; if ( !akid ) { cluster = append_cluster(node, cluster, &ncluster, tmp); continue; } if ( node->value >= cutoff && akid->value < cutoff ) cluster = append_cluster(akid, cluster, &ncluster, tmp); else stack[nstack++] = akid; if ( node->value >= cutoff && bkid->value < cutoff ) cluster = append_cluster(bkid, cluster, &ncluster, tmp); else stack[nstack++] = bkid; } free(tmp); free(stack); *nclust = ncluster; return cluster; } void hclust_destroy_list(cluster_t *clust, int nclust) { int i; for (i=0; i Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Simple hierarchical clustering */ #ifndef __HCLUST_H__ #define __HCLUST_H__ #include typedef struct _hclust_t hclust_t; typedef struct { float dist; int nmemb, *memb; } cluster_t; #define PDIST(mat,a,b) (mat)[((a)>(b)?((a)*((a)-1)/2+(b)):((b)*((b)-1)/2+(a)))] /* * hclust_init() - init and run clustering * @n: number of elements * @pdist: pairwise distances. The array will be modified by hclust and * must exist until hclust_destroy() is called */ hclust_t *hclust_init(int n, float *pdist); void hclust_destroy(hclust_t *clust); /* * hclust_create_list() - returns a list of clusters * @min_inter_dist: minimum inter-cluster distance. If smaller, elements are considered * homogenous, belonging to the same cluster. * @max_intra_dist: maximum intra-cluster distance allowed. If smaller than 0, * the threshold can be heuristically lowered, otherwise considered * a fixed cutoff. The pointer will be filled to the cutoff actually used. */ cluster_t *hclust_create_list(hclust_t *clust, float min_inter_dist, float *max_intra_dist, int *nclust); void hclust_destroy_list(cluster_t *clust, int nclust); /* * Access debugging data used in the decision making process. Note that this * must be called immediately after hclust_create_list because other calls, * such as hclust_create_dot(), invalidate the temporary data structures. */ char **hclust_explain(hclust_t *clust, int *nlines); char *hclust_create_dot(hclust_t *clust, char **labels, float th); #endif bcftools-1.21/hex.h000066400000000000000000000057151467060157400142270ustar00rootroot00000000000000// VariantKey // // hex.h // // @category Libraries // @author Nicola Asuni // @link https://github.com/tecnickcom/variantkey // @license MIT [LICENSE](https://raw.githubusercontent.com/tecnickcom/variantkey/main/LICENSE) // @copyright 2017-2018 GENOMICS plc // // LICENSE // // Copyright (c) 2017-2018 GENOMICS plc // // Permission is hereby granted, free of charge, to any person obtaining a copy // of this software and associated documentation files (the "Software"), to deal // in the Software without restriction, including without limitation the rights // to use, copy, modify, merge, publish, distribute, sublicense, and/or sell // copies of the Software, and to permit persons to whom the Software is // furnished to do so, subject to the following conditions: // // The above copyright notice and this permission notice shall be included in // all copies or substantial portions of the Software. // // THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR // IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, // FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE // AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER // LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, // OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN // THE SOFTWARE. /** * @file hex.h * @brief Utility functions to manipulate strings. * * Collection of utility functions to manipulate strings. */ #ifndef ASTRING_H #define ASTRING_H #include #include /** @brief Returns uint64_t hexadecimal string (16 characters). * * @param n Number to parse * @param str String buffer to be returned (it must be sized 17 bytes at least). * * @return Upon successful return, these function returns the number of characters processed * (excluding the null byte used to end output to strings). * If the buffer size is not sufficient, then the return value is the number of characters required for * buffer string, including the terminating null byte. */ static inline size_t hex_uint64_t(uint64_t n, char *str) { return sprintf(str, "%016" PRIx64, n); } /** @brief Parses a 16 chars hexadecimal string and returns the code. * * @param s Hexadecimal string to parse (it must contain 16 hexadecimal characters). * * @return uint64_t unsigned integer number. */ static inline uint64_t parse_hex_uint64_t(const char *s) { uint64_t v = 0; uint8_t b; size_t i; for (i = 0; i < 16; i++) { b = s[i]; if (b >= 'a') { b -= ('a' - 10); // a-f } else { if (b >= 'A') { b -= ('A' - 10); // A-F } else { b -= '0'; // 0-9 } } v = ((v << 4) | b); } return v; } #endif // ASTRING_H bcftools-1.21/install-sh000077500000000000000000000345231467060157400152750ustar00rootroot00000000000000#!/bin/sh # install - install a program, script, or datafile scriptversion=2013-12-25.23; # UTC # This originates from X11R5 (mit/util/scripts/install.sh), which was # later released in X11R6 (xc/config/util/install.sh) with the # following copyright and license. # # Copyright (C) 1994 X Consortium # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to # deal in the Software without restriction, including without limitation the # rights to use, copy, modify, merge, publish, distribute, sublicense, and/or # sell copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE # X CONSORTIUM BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN # AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNEC- # TION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. # # Except as contained in this notice, the name of the X Consortium shall not # be used in advertising or otherwise to promote the sale, use or other deal- # ings in this Software without prior written authorization from the X Consor- # tium. # # # FSF changes to this file are in the public domain. # # Calling this script install-sh is preferred over install.sh, to prevent # 'make' implicit rules from creating a file called install from it # when there is no Makefile. # # This script is compatible with the BSD install script, but was written # from scratch. tab=' ' nl=' ' IFS=" $tab$nl" # Set DOITPROG to "echo" to test this script. doit=${DOITPROG-} doit_exec=${doit:-exec} # Put in absolute file names if you don't have them in your path; # or use environment vars. chgrpprog=${CHGRPPROG-chgrp} chmodprog=${CHMODPROG-chmod} chownprog=${CHOWNPROG-chown} cmpprog=${CMPPROG-cmp} cpprog=${CPPROG-cp} mkdirprog=${MKDIRPROG-mkdir} mvprog=${MVPROG-mv} rmprog=${RMPROG-rm} stripprog=${STRIPPROG-strip} posix_mkdir= # Desired mode of installed file. mode=0755 chgrpcmd= chmodcmd=$chmodprog chowncmd= mvcmd=$mvprog rmcmd="$rmprog -f" stripcmd= src= dst= dir_arg= dst_arg= copy_on_change=false is_target_a_directory=possibly usage="\ Usage: $0 [OPTION]... [-T] SRCFILE DSTFILE or: $0 [OPTION]... SRCFILES... DIRECTORY or: $0 [OPTION]... -t DIRECTORY SRCFILES... or: $0 [OPTION]... -d DIRECTORIES... In the 1st form, copy SRCFILE to DSTFILE. In the 2nd and 3rd, copy all SRCFILES to DIRECTORY. In the 4th, create DIRECTORIES. Options: --help display this help and exit. --version display version info and exit. -c (ignored) -C install only if different (preserve the last data modification time) -d create directories instead of installing files. -g GROUP $chgrpprog installed files to GROUP. -m MODE $chmodprog installed files to MODE. -o USER $chownprog installed files to USER. -s $stripprog installed files. -t DIRECTORY install into DIRECTORY. -T report an error if DSTFILE is a directory. Environment variables override the default commands: CHGRPPROG CHMODPROG CHOWNPROG CMPPROG CPPROG MKDIRPROG MVPROG RMPROG STRIPPROG " while test $# -ne 0; do case $1 in -c) ;; -C) copy_on_change=true;; -d) dir_arg=true;; -g) chgrpcmd="$chgrpprog $2" shift;; --help) echo "$usage"; exit $?;; -m) mode=$2 case $mode in *' '* | *"$tab"* | *"$nl"* | *'*'* | *'?'* | *'['*) echo "$0: invalid mode: $mode" >&2 exit 1;; esac shift;; -o) chowncmd="$chownprog $2" shift;; -s) stripcmd=$stripprog;; -t) is_target_a_directory=always dst_arg=$2 # Protect names problematic for 'test' and other utilities. case $dst_arg in -* | [=\(\)!]) dst_arg=./$dst_arg;; esac shift;; -T) is_target_a_directory=never;; --version) echo "$0 $scriptversion"; exit $?;; --) shift break;; -*) echo "$0: invalid option: $1" >&2 exit 1;; *) break;; esac shift done # We allow the use of options -d and -T together, by making -d # take the precedence; this is for compatibility with GNU install. if test -n "$dir_arg"; then if test -n "$dst_arg"; then echo "$0: target directory not allowed when installing a directory." >&2 exit 1 fi fi if test $# -ne 0 && test -z "$dir_arg$dst_arg"; then # When -d is used, all remaining arguments are directories to create. # When -t is used, the destination is already specified. # Otherwise, the last argument is the destination. 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Create the # directory the slow way, step by step, checking for races as we go. case $dstdir in /*) prefix='/';; [-=\(\)!]*) prefix='./';; *) prefix='';; esac oIFS=$IFS IFS=/ set -f set fnord $dstdir shift set +f IFS=$oIFS prefixes= for d do test X"$d" = X && continue prefix=$prefix$d if test -d "$prefix"; then prefixes= else if $posix_mkdir; then (umask=$mkdir_umask && $doit_exec $mkdirprog $mkdir_mode -p -- "$dstdir") && break # Don't fail if two instances are running concurrently. test -d "$prefix" || exit 1 else case $prefix in *\'*) qprefix=`echo "$prefix" | sed "s/'/'\\\\\\\\''/g"`;; *) qprefix=$prefix;; esac prefixes="$prefixes '$qprefix'" fi fi prefix=$prefix/ done if test -n "$prefixes"; then # Don't fail if two instances are running concurrently. (umask $mkdir_umask && eval "\$doit_exec \$mkdirprog $prefixes") || test -d "$dstdir" || exit 1 obsolete_mkdir_used=true fi fi fi if test -n "$dir_arg"; then { test -z "$chowncmd" || $doit $chowncmd "$dst"; } && { test -z "$chgrpcmd" || $doit $chgrpcmd "$dst"; } && { test "$obsolete_mkdir_used$chowncmd$chgrpcmd" = false || test -z "$chmodcmd" || $doit $chmodcmd $mode "$dst"; } || exit 1 else # Make a couple of temp file names in the proper directory. dsttmp=$dstdir/_inst.$$_ rmtmp=$dstdir/_rm.$$_ # Trap to clean up those temp files at exit. trap 'ret=$?; rm -f "$dsttmp" "$rmtmp" && exit $ret' 0 # Copy the file name to the temp name. (umask $cp_umask && $doit_exec $cpprog "$src" "$dsttmp") && # and set any options; do chmod last to preserve setuid bits. # # If any of these fail, we abort the whole thing. If we want to # ignore errors from any of these, just make sure not to ignore # errors from the above "$doit $cpprog $src $dsttmp" command. # { test -z "$chowncmd" || $doit $chowncmd "$dsttmp"; } && { test -z "$chgrpcmd" || $doit $chgrpcmd "$dsttmp"; } && { test -z "$stripcmd" || $doit $stripcmd "$dsttmp"; } && { test -z "$chmodcmd" || $doit $chmodcmd $mode "$dsttmp"; } && # If -C, don't bother to copy if it wouldn't change the file. if $copy_on_change && old=`LC_ALL=C ls -dlL "$dst" 2>/dev/null` && new=`LC_ALL=C ls -dlL "$dsttmp" 2>/dev/null` && set -f && set X $old && old=:$2:$4:$5:$6 && set X $new && new=:$2:$4:$5:$6 && set +f && test "$old" = "$new" && $cmpprog "$dst" "$dsttmp" >/dev/null 2>&1 then rm -f "$dsttmp" else # Rename the file to the real destination. $doit $mvcmd -f "$dsttmp" "$dst" 2>/dev/null || # The rename failed, perhaps because mv can't rename something else # to itself, or perhaps because mv is so ancient that it does not # support -f. { # Now remove or move aside any old file at destination location. # We try this two ways since rm can't unlink itself on some # systems and the destination file might be busy for other # reasons. In this case, the final cleanup might fail but the new # file should still install successfully. { test ! -f "$dst" || $doit $rmcmd -f "$dst" 2>/dev/null || { $doit $mvcmd -f "$dst" "$rmtmp" 2>/dev/null && { $doit $rmcmd -f "$rmtmp" 2>/dev/null; :; } } || { echo "$0: cannot unlink or rename $dst" >&2 (exit 1); exit 1 } } && # Now rename the file to the real destination. $doit $mvcmd "$dsttmp" "$dst" } fi || exit 1 trap '' 0 fi done # Local variables: # eval: (add-hook 'write-file-hooks 'time-stamp) # time-stamp-start: "scriptversion=" # time-stamp-format: "%:y-%02m-%02d.%02H" # time-stamp-time-zone: "UTC" # time-stamp-end: "; # UTC" # End: bcftools-1.21/khash_str2str.h000066400000000000000000000061331467060157400162370ustar00rootroot00000000000000/* khash_str2str.h -- C-string to C-string hash table. Copyright (C) 2014,2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef KHASH_STR2STR_H #define KHASH_STR2STR_H #include KHASH_MAP_INIT_STR(str2str, const char*) /* * Wrappers for khash dictionaries used by mpileup. */ static inline void *khash_str2str_init(void) { return kh_init(str2str); } /* * Destroy the hash structure, but not the keys */ static inline void khash_str2str_destroy(void *_hash) { khash_t(str2str) *hash = (khash_t(str2str)*)_hash; if (hash) kh_destroy(str2str, hash); // Note that strings are not freed. } /* * Destroys both the hash structure and the keys */ static inline void khash_str2str_destroy_free(void *_hash) { khash_t(str2str) *hash = (khash_t(str2str)*)_hash; khint_t k; if (hash == 0) return; for (k = 0; k < kh_end(hash); ++k) if (kh_exist(hash, k)) free((char*)kh_key(hash, k)); kh_destroy(str2str, hash); } /* * Destroys the hash structure, the keys and the values */ static inline void khash_str2str_destroy_free_all(void *_hash) { khash_t(str2str) *hash = (khash_t(str2str)*)_hash; khint_t k; if (hash == 0) return; for (k = 0; k < kh_end(hash); ++k) if (kh_exist(hash, k)) { free((char*)kh_key(hash, k)); free((char*)kh_val(hash, k)); } kh_destroy(str2str, hash); } /* * Returns value if key exists or NULL if not */ static inline char *khash_str2str_get(void *_hash, const char *str) { khash_t(str2str) *hash = (khash_t(str2str)*)_hash; khint_t k = kh_get(str2str, hash, str); if ( k == kh_end(hash) ) return NULL; return (char*)kh_val(hash, k); } /* * Set a new key,value pair. On success returns the bin index, on * error -1 is returned. */ static inline int khash_str2str_set(void *_hash, const char *str, const char *value) { khint_t k; int ret; khash_t(str2str) *hash = (khash_t(str2str)*)_hash; if ( !hash ) return -1; k = kh_put(str2str, hash, str, &ret); kh_val(hash,k) = value; return k; } #endif bcftools-1.21/kheap.h000066400000000000000000000170561467060157400145340ustar00rootroot00000000000000/* The MIT License Copyright (C) 2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Usage example: #include "kheap.h" // First we prepare the user data to store, in this example it is a // struct with a single element "key", and a comparator function // "is_smaller". In this example the comparator defines a min heap (as // opposed to a max heap). typedef struct { uint32_t key; } data_t; static inline int is_smaller(data_t *a, data_t *b) { return a->key < b->key ? 1 : 0; } data_t data[3] = { {3}, {2}, {1} }; // Heap declaration, "mh" is an arbitrary string. The typedef is not // required, it is just a convenience shortcut so that we can use // "heap_t" instead of the generic "khp_mh_t" automatically created by // the KHEAP_INIT macro. KHEAP_INIT(mh, data_t, is_smaller) typedef khp_mh_t heap_t; // Initialize the heap, insert the test data, then retrieve them back, // sorted. Multiple heaps with the same name "mh" can be created and // used simultaneously, as long as they all use the same data type // "data_t". heap_t *heap = khp_init(mh); // When inserting a new element, the heap stores a copy of the memory // area pointed to by the third argument. for (int i=0; i<3; i++) khp_insert(mh, heap, &data[i]); while (heap->ndat) { printf("%d\n", heap->dat[0].pos); khp_delete(mh, heap); } // Clean up khp_destroy(mh, heap); */ #ifndef __KHEAP_H__ #define __KHEAP_H__ #include #ifndef kroundup32 #define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x)) #endif #ifndef kh_inline #ifdef _MSC_VER #define kh_inline __inline #else #define kh_inline inline #endif #endif /* kh_inline */ #ifndef klib_unused #if (defined __clang__ && __clang_major__ >= 3) || (defined __GNUC__ && __GNUC__ >= 3) #define klib_unused __attribute__ ((__unused__)) #else #define klib_unused #endif #endif /* klib_unused */ #define __KHEAP_TYPE(name, kheap_t) \ typedef struct { \ int ndat, mdat; \ kheap_t *dat; \ kheap_t tmp; \ } khp_##name##_t; #define khp_parent(i) (((i)-1)/2) #define khp_lchild(i) (2*(i)+1) #define khp_rchild(i) (2*(i)+2) #define khp_swap(hp,i,j) { \ ((hp)->tmp) = ((hp)->dat[i]); \ ((hp)->dat[i]) = ((hp)->dat[j]); \ ((hp)->dat[j]) = ((hp)->tmp); \ } #define __KHEAP_IMPL(name, SCOPE, kheap_t, __cmp) \ SCOPE khp_##name##_t *khp_init_##name(void) \ { \ return (khp_##name##_t*)calloc(1, sizeof(khp_##name##_t)); \ } \ SCOPE void khp_destroy_##name(khp_##name##_t *heap) \ { \ if (heap) free(heap->dat); \ free(heap); \ } \ SCOPE int khp_insert_##name(khp_##name##_t *heap, kheap_t *dat) \ { \ heap->ndat++; \ if ( heap->ndat > heap->mdat ) \ { \ heap->mdat = heap->ndat; \ kroundup32(heap->mdat); \ heap->dat = (kheap_t*)realloc(heap->dat, heap->mdat*sizeof(kheap_t)); \ memset(heap->dat + heap->ndat, 0, (heap->mdat - heap->ndat)*sizeof(kheap_t)); \ } \ int i = heap->ndat - 1; \ while ( i && __cmp(dat,&heap->dat[khp_parent(i)]) ) \ { \ heap->dat[i] = heap->dat[khp_parent(i)]; \ i = khp_parent(i); \ } \ heap->dat[i] = *dat; \ return i; \ } \ SCOPE void khp_heapify_##name(khp_##name##_t *heap, int i) \ { \ /*todo: loop instead of a recursive function? */ \ int extreme = khp_lchild(i) < heap->ndat && __cmp(&heap->dat[khp_lchild(i)],&heap->dat[i]) ? khp_lchild(i) : i; \ if ( khp_rchild(i) < heap->ndat && __cmp(&heap->dat[khp_rchild(i)],&heap->dat[extreme]) ) extreme = khp_rchild(i); \ if ( extreme != i ) \ { \ khp_swap(heap,i,extreme); \ khp_heapify_##name(heap,extreme); \ } \ } \ SCOPE void khp_delete_##name(khp_##name##_t *heap) \ { \ if ( !heap || !heap->ndat ) return; \ heap->dat[0] = heap->dat[--heap->ndat]; \ khp_heapify_##name(heap, 0); \ } \ #define KHEAP_INIT(name, kheap_t, __cmp) \ __KHEAP_TYPE(name, kheap_t) \ __KHEAP_IMPL(name, static kh_inline klib_unused, kheap_t, __cmp) #define khp_init(name) khp_init_##name() #define khp_destroy(name, heap) khp_destroy_##name(heap) #define khp_insert(name, heap, dat) khp_insert_##name(heap, dat) #define khp_delete(name, heap) khp_delete_##name(heap) #endif bcftools-1.21/kmin.c000066400000000000000000000161451467060157400143730ustar00rootroot00000000000000/* The MIT License Copyright (c) 2008, 2010 by Attractive Chaos Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Hooke-Jeeves algorithm for nonlinear minimization Based on the pseudocodes by Bell and Pike (CACM 9(9):684-685), and the revision by Tomlin and Smith (CACM 12(11):637-638). Both of the papers are comments on Kaupe's Algorithm 178 "Direct Search" (ACM 6(6):313-314). The original algorithm was designed by Hooke and Jeeves (ACM 8:212-229). This program is further revised according to Johnson's implementation at Netlib (opt/hooke.c). Hooke-Jeeves algorithm is very simple and it works quite well on a few examples. However, it might fail to converge due to its heuristic nature. A possible improvement, as is suggested by Johnson, may be to choose a small r at the beginning to quickly approach to the minimum and a large r at later step to hit the minimum. */ #include #include #include #include "kmin.h" static double __kmin_hj_aux(kmin_f func, int n, double *x1, void *data, double fx1, double *dx, int *n_calls) { int k, j = *n_calls; double ftmp; for (k = 0; k != n; ++k) { x1[k] += dx[k]; ftmp = func(n, x1, data); ++j; if (ftmp < fx1) fx1 = ftmp; else { /* search the opposite direction */ dx[k] = 0.0 - dx[k]; x1[k] += dx[k] + dx[k]; ftmp = func(n, x1, data); ++j; if (ftmp < fx1) fx1 = ftmp; else x1[k] -= dx[k]; /* back to the original x[k] */ } } *n_calls = j; return fx1; /* here: fx1=f(n,x1) */ } double kmin_hj(kmin_f func, int n, double *x, void *data, double r, double eps, int max_calls) { double fx, fx1, *x1, *dx, radius; int k, n_calls = 0; x1 = (double*)calloc(n, sizeof(double)); dx = (double*)calloc(n, sizeof(double)); for (k = 0; k != n; ++k) { /* initial directions, based on MGJ */ dx[k] = fabs(x[k]) * r; if (dx[k] == 0) dx[k] = r; } radius = r; fx1 = fx = func(n, x, data); ++n_calls; for (;;) { memcpy(x1, x, n * sizeof(double)); /* x1 = x */ fx1 = __kmin_hj_aux(func, n, x1, data, fx, dx, &n_calls); while (fx1 < fx) { for (k = 0; k != n; ++k) { double t = x[k]; dx[k] = x1[k] > x[k]? fabs(dx[k]) : 0.0 - fabs(dx[k]); x[k] = x1[k]; x1[k] = x1[k] + x1[k] - t; } fx = fx1; if (n_calls >= max_calls) break; fx1 = func(n, x1, data); ++n_calls; fx1 = __kmin_hj_aux(func, n, x1, data, fx1, dx, &n_calls); if (fx1 >= fx) break; for (k = 0; k != n; ++k) if (fabs(x1[k] - x[k]) > .5 * fabs(dx[k])) break; if (k == n) break; } if (radius >= eps) { if (n_calls >= max_calls) break; radius *= r; for (k = 0; k != n; ++k) dx[k] *= r; } else break; /* converge */ } free(x1); free(dx); return fx1; } // I copied this function somewhere several years ago with some of my modifications, but I forgot the source. double kmin_brent(kmin1_f func, double a, double b, void *data, double tol, double *xmin) { double bound, u, r, q, fu, tmp, fa, fb, fc, c; const double gold1 = 1.6180339887; const double gold2 = 0.3819660113; const double tiny = 1e-20; const int max_iter = 100; double e, d, w, v, mid, tol1, tol2, p, eold, fv, fw; int iter; fa = func(a, data); fb = func(b, data); if (fb > fa) { // swap, such that f(a) > f(b) tmp = a; a = b; b = tmp; tmp = fa; fa = fb; fb = tmp; } c = b + gold1 * (b - a), fc = func(c, data); // golden section extrapolation while (fb > fc) { bound = b + 100.0 * (c - b); // the farthest point where we want to go r = (b - a) * (fb - fc); q = (b - c) * (fb - fa); if (fabs(q - r) < tiny) { // avoid 0 denominator tmp = q > r? tiny : 0.0 - tiny; } else tmp = q - r; u = b - ((b - c) * q - (b - a) * r) / (2.0 * tmp); // u is the parabolic extrapolation point if ((b > u && u > c) || (b < u && u < c)) { // u lies between b and c fu = func(u, data); if (fu < fc) { // (b,u,c) bracket the minimum a = b; b = u; fa = fb; fb = fu; break; } else if (fu > fb) { // (a,b,u) bracket the minimum c = u; fc = fu; break; } u = c + gold1 * (c - b); fu = func(u, data); // golden section extrapolation } else if ((c > u && u > bound) || (c < u && u < bound)) { // u lies between c and bound fu = func(u, data); if (fu < fc) { // fb > fc > fu b = c; c = u; u = c + gold1 * (c - b); fb = fc; fc = fu; fu = func(u, data); } else { // (b,c,u) bracket the minimum a = b; b = c; c = u; fa = fb; fb = fc; fc = fu; break; } } else if ((u > bound && bound > c) || (u < bound && bound < c)) { // u goes beyond the bound u = bound; fu = func(u, data); } else { // u goes the other way around, use golden section extrapolation u = c + gold1 * (c - b); fu = func(u, data); } a = b; b = c; c = u; fa = fb; fb = fc; fc = fu; } if (a > c) u = a, a = c, c = u; // swap // now, afb and fb tol1) { // related to parabolic interpolation r = (b - w) * (fb - fv); q = (b - v) * (fb - fw); p = (b - v) * q - (b - w) * r; q = 2.0 * (q - r); if (q > 0.0) p = 0.0 - p; else q = 0.0 - q; eold = e; e = d; if (fabs(p) >= fabs(0.5 * q * eold) || p <= q * (a - b) || p >= q * (c - b)) { d = gold2 * (e = (b >= mid ? a - b : c - b)); } else { d = p / q; u = b + d; // actual parabolic interpolation happens here if (u - a < tol2 || c - u < tol2) d = (mid > b)? tol1 : 0.0 - tol1; } } else d = gold2 * (e = (b >= mid ? a - b : c - b)); // golden section interpolation u = fabs(d) >= tol1 ? b + d : b + (d > 0.0? tol1 : -tol1); fu = func(u, data); if (fu <= fb) { // u is the minimum point so far if (u >= b) a = b; else c = b; v = w; w = b; b = u; fv = fw; fw = fb; fb = fu; } else { // adjust (a,c) and (u,v,w) if (u < b) a = u; else c = u; if (fu <= fw || w == b) { v = w; w = u; fv = fw; fw = fu; } else if (fu <= fv || v == b || v == w) { v = u; fv = fu; } } } *xmin = b; return fb; } bcftools-1.21/kmin.h000066400000000000000000000031231467060157400143700ustar00rootroot00000000000000/* Copyright (c) 2008, 2010 by Attractive Chaos Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef KMIN_H #define KMIN_H #define KMIN_RADIUS 0.5 #define KMIN_EPS 1e-7 #define KMIN_MAXCALL 50000 typedef double (*kmin_f)(int, double*, void*); typedef double (*kmin1_f)(double, void*); #ifdef __cplusplus extern "C" { #endif double kmin_hj(kmin_f func, int n, double *x, void *data, double r, double eps, int max_calls); double kmin_brent(kmin1_f func, double a, double b, void *data, double tol, double *xmin); #ifdef __cplusplus } #endif #endif bcftools-1.21/m4/000077500000000000000000000000001467060157400136025ustar00rootroot00000000000000bcftools-1.21/m4/ax_with_htslib.m4000066400000000000000000000124611467060157400170600ustar00rootroot00000000000000# =========================================================================== # http://www.gnu.org/software/autoconf-archive/ax_with_htslib.html # =========================================================================== # # SYNOPSIS # # AX_WITH_HTSLIB # # DESCRIPTION # # This macro checks whether HTSlib is installed # or nearby, and adds a --with-htslib=DIR option to the configure script # for specifying the location. It locates either an installation prefix # (with 'include' and 'lib' subdirectories) or an HTSlib source tree, as # HTSlib is fast-moving and users may wish to use an in-development tree. # # Different checks occur depending on the --with-htslib argument given: # # With --with-htslib=DIR, checks whether DIR is a source tree (including # a separate build tree) or contains a working installation. # By default, searches for a source tree (with a name matching htslib*) # within or alongside $srcdir. Produces AC_MSG_ERROR if there are # several equally-likely candidates. If there are none, checks for # a working default installation. # With --with-htslib=system, checks for a working default installation. # # If a source tree is found or specified, it is added to AC_CONFIG_SUBDIRS # if either --enable-configure-htslib is set, or where htslib is included # in a subdirectory (for packages that want to supply an embedded htslib). # Unfortunately this may cause a "you should use literals" warning when # autoconf is run. # # The following output variables are set by this macro: # # HTSDIR Directory containing HTSlib source tree # HTSLIB_CPPFLAGS Preprocessor flags for compiling with HTSlib # HTSLIB_LDFLAGS Linker flags for linking with HTSlib # # The following shell variables may be defined: # # ax_cv_htslib Set to "yes" if HTSlib was found # ax_cv_htslib_which Set to "source", "install", or "none" # # LICENSE # # Copyright (C) 2015, 2017, 2021 Genome Research Ltd # # Copying and distribution of this file, with or without modification, are # permitted in any medium without royalty provided the copyright notice # and this notice are preserved. This file is offered as-is, without any # warranty. #serial 3 AC_DEFUN([AX_WITH_HTSLIB], [AC_ARG_WITH([htslib], [AS_HELP_STRING([--with-htslib=DIR], [use the HTSlib source tree or installation in DIR]) dnl Not indented, to avoid extra whitespace outwith AS_HELP_STRING() AS_HELP_STRING([--with-htslib=system], [use only a system HTSlib installation])], [], [with_htslib=search]) AC_ARG_ENABLE([configure-htslib], [AS_HELP_STRING([--enable-configure-htslib], [run configure for htslib as well @<:@default=only_in_subdir@:>@])], [], [enable_configure_htslib=only_in_subdir]) case $with_htslib in yes|search) AC_MSG_CHECKING([location of HTSlib source tree]) case $srcdir in .) srcp= ;; *) srcp=$srcdir/ ;; esac found= for dir in ${srcp}htslib* -- ${srcp}../htslib -- ${srcp}../htslib* do if test "$dir" = "--"; then test -n "$found" && break elif test -f "$dir/hts.c" && test -f "$dir/htslib/hts.h"; then found="${found}1" HTSDIR=$dir fi done if test -z "$found"; then AC_MSG_RESULT([none found]) ax_cv_htslib_which=system elif test "$found" = 1; then AC_MSG_RESULT([$HTSDIR]) ax_cv_htslib_which=source if test "x$enable_configure_htslib" = "xonly_in_subdir" ; then case $HTSDIR in "${srcp}htslib"*) enable_configure_htslib=yes ;; *) ;; esac fi else AC_MSG_RESULT([several directories found]) AC_MSG_ERROR([use --with-htslib=DIR to select which HTSlib to use]) fi ;; no) ax_cv_htslib_which=none ;; system) ax_cv_htslib_which=system ;; *) HTSDIR=$with_htslib if test -f "$HTSDIR/hts.c" && test -f "$HTSDIR/htslib/hts.h"; then ax_cv_htslib_which=source elif test -f "$HTSDIR/htslib_vars.mk"; then ax_cv_htslib_which=build else ax_cv_htslib_which=install fi ;; esac case $ax_cv_htslib_which in source) ax_cv_htslib=yes HTSLIB_CPPFLAGS="-I$HTSDIR" HTSLIB_LDFLAGS="-L$HTSDIR" if test "x$enable_configure_htslib" = "xyes"; then # We can't use a literal, because $HTSDIR is user-provided and variable AC_CONFIG_SUBDIRS($HTSDIR) fi ;; build) ax_cv_htslib=yes ax_cv_htslib_which=source # Ensure this is fully expanded, as the caller might not be using @HTSDIR@ HTSSRCDIR=$(sed -n 's:\$(HTSDIR):'$HTSDIR': s/^HTSSRCDIR *= *//p' "$HTSDIR/htslib_vars.mk") HTSLIB_CPPFLAGS="-I$HTSSRCDIR" HTSLIB_LDFLAGS="-L$HTSDIR" ;; system) AC_CHECK_HEADER([htslib/sam.h], [AC_CHECK_LIB(hts, hts_version, [ax_cv_htslib=yes], [ax_cv_htslib=no])], [ax_cv_htslib=no], [;]) ax_cv_htslib_which=install HTSDIR= HTSLIB_CPPFLAGS= HTSLIB_LDFLAGS= ;; install) ax_saved_CPPFLAGS=$CPPFLAGS ax_saved_LDFLAGS=$LDFLAGS HTSLIB_CPPFLAGS="-I$HTSDIR/include" HTSLIB_LDFLAGS="-L$HTSDIR/lib" CPPFLAGS="$CPPFLAGS $HTSLIB_CPPFLAGS" LDFLAGS="$LDFLAGS $HTSLIB_LDFLAGS" AC_CHECK_HEADER([htslib/sam.h], [AC_CHECK_LIB(hts, hts_version, [ax_cv_htslib=yes], [ax_cv_htslib=no])], [ax_cv_htslib=no], [;]) HTSDIR= CPPFLAGS=$ax_saved_CPPFLAGS LDFLAGS=$ax_saved_LDFLAGS ;; none) ax_cv_htslib=no ;; esac AC_SUBST([HTSDIR]) AC_SUBST([HTSLIB_CPPFLAGS]) AC_SUBST([HTSLIB_LDFLAGS])]) bcftools-1.21/m4/hts_prog_cc_warnings.m4000066400000000000000000000201221467060157400202430ustar00rootroot00000000000000dnl @synopsis HTS_PROG_CC_WARNINGS([ANSI]) dnl dnl Derived from dnl http://ac-archive.sourceforge.net/ac-archive/vl_prog_cc_warnings.html dnl dnl Enables a reasonable set of warnings for the C compiler. dnl Optionally, if the first argument is nonempty, turns on flags which dnl enforce and/or enable proper ANSI C if such are known with the dnl compiler used. dnl dnl Currently this macro knows about GCC, Solaris C compiler, Digital dnl Unix C compiler, C for AIX Compiler, HP-UX C compiler, IRIX C dnl compiler, NEC SX-5 (Super-UX 10) C compiler, and Cray J90 (Unicos dnl 10.0.0.8) C compiler. dnl dnl @category C dnl @author Ville Laurikari dnl Updated by Rob Davies for HTSlib dnl @license AllPermissive dnl Copying and distribution of this file, with or without modification, dnl are permitted in any medium without royalty provided the copyright notice dnl and this notice are preserved. Users of this software should generally dnl follow the principles of the MIT License including its disclaimer. dnl Original Copyright (c) Ville Laurikari 2002 dnl Modifications Copyright (c) Genome Research Limited 2015,2017 AC_DEFUN([HTS_PROG_CC_WARNINGS], [ AC_ARG_ENABLE([warnings], [AS_HELP_STRING([--disable-warnings], [turn off compiler warnings])], [], [enable_warnings=yes]) AS_IF([test "x$enable_warnings" != xno],[ AC_REQUIRE([AC_PROG_GREP]) ansi="$1" AS_IF([test "x$ansi" = "x"], [msg="for C compiler warning flags"], [msg="for C compiler warning and ANSI conformance flags"]) AC_MSG_CHECKING($msg) AC_CACHE_VAL(hts_cv_prog_cc_warnings, [dnl hts_cv_prog_cc_warnings="" AS_IF([test "x$CC" != "x"],[ cat > conftest.c < /dev/null 2>&1 && test -f conftest.o],[dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-Wall"], [hts_cv_prog_cc_warnings="-Wall -ansi -pedantic"]) ], # Sun Studio or Solaris C compiler ["$CC" -V 2>&1 | $GREP -i -E "WorkShop|Sun C" > /dev/null 2>&1 && "$CC" -c -v -Xc conftest.c > /dev/null 2>&1 && test -f conftest.o],[dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-v"], [hts_cv_prog_cc_warnings="-v -Xc"]) ], # Digital Unix C compiler ["$CC" -V 2>&1 | $GREP -i "Digital UNIX Compiler" > /dev/null 2>&1 && "$CC" -c -verbose -w0 -warnprotos -std1 conftest.c > /dev/null 2>&1 && test -f conftest.o], [dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-verbose -w0 -warnprotos"], [hts_cv_prog_cc_warnings="-verbose -w0 -warnprotos -std1"]) ], # C for AIX Compiler ["$CC" 2>&1 | $GREP -i "C for AIX Compiler" > /dev/null 2>&1 && "$CC" -c -qlanglvl=ansi -qinfo=all conftest.c > /dev/null 2>&1 && test -f conftest.o],[dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-qsrcmsg -qinfo=all:noppt:noppc:noobs:nocnd"], [hts_cv_prog_cc_warnings="-qsrcmsg -qinfo=all:noppt:noppc:noobs:nocnd -qlanglvl=ansi"]) ], # IRIX C compiler ["$CC" -version 2>&1 | $GREP -i "MIPSpro Compilers" > /dev/null 2>&1 && "$CC" -c -fullwarn -ansi -ansiE conftest.c > /dev/null 2>&1 && test -f conftest.o],[dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-fullwarn"], [hts_cv_prog_cc_warnings="-fullwarn -ansi -ansiE"]) ], # HP-UX C compiler [what "$CC" 2>&1 | $GREP -i "HP C Compiler" > /dev/null 2>&1 && "$CC" -c -Aa +w1 conftest.c > /dev/null 2>&1 && test -f conftest.o],[dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="+w1"], [hts_cv_prog_cc_warnings="+w1 -Aa"]) ], # The NEC SX series (Super-UX 10) C compiler ["$CC" -V 2>&1 | $GREP "/SX" > /dev/null 2>&1 && "$CC" -c -pvctl[,]fullmsg -Xc conftest.c > /dev/null 2>&1 && test -f conftest.o],[ AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-pvctl[,]fullmsg"], [hts_cv_prog_cc_warnings="-pvctl[,]fullmsg -Xc"]) ], # The Cray C compiler (Unicos) ["$CC" -V 2>&1 | $GREP -i "Cray" > /dev/null 2>&1 && "$CC" -c -h msglevel_2 conftest.c > /dev/null 2>&1 && test -f conftest.o],[dnl AS_IF([test "x$ansi" = "x"], [hts_cv_prog_cc_warnings="-h#msglevel_2"], [hts_cv_prog_cc_warnings="-h#msglevel_2,conform"]) ], # The Tiny C Compiler ["$CC" -v 2>&1 | $GREP "tcc version" > /dev/null && "$CC" -Wall -c conftest.c > /dev/null 2>&1 && test -f conftest.o],[dnl hts_cv_prog_cc_warnings="-Wall" ]) rm -f conftest.* ]) ]) AS_IF([test "x$hts_cv_prog_cc_warnings" != "x"],[ dnl Print result, with underscores as spaces ac_arg_result=`echo "$hts_cv_prog_cc_warnings" | tr '#' ' '` AC_MSG_RESULT($ac_arg_result) dnl Add options to CFLAGS only if they are not already present ac_arg_needed="" for ac_arg in $hts_cv_prog_cc_warnings do ac_arg_sp=`echo "$ac_arg" | tr '#' ' '` AS_CASE([" $CFLAGS "], [*" $ac_arg_sp "*], [], [ac_arg_needed="$ac_arg_all $ac_arg_sp"]) done CFLAGS="$ac_arg_needed $CFLAGS"],[dnl AC_MSG_RESULT(unknown) ]) ]) ])dnl HTS_PROG_CC_WARNINGS # SYNOPSIS # # HTS_PROG_CC_WERROR(FLAGS_VAR) # # Set FLAGS_VAR to the flags needed to make the C compiler treat warnings # as errors. AC_DEFUN([HTS_PROG_CC_WERROR], [ AC_ARG_ENABLE([werror], [AS_HELP_STRING([--enable-werror], [change warnings into errors, where supported])], [enable_werror=yes], []) AS_IF([test "x$enable_werror" = xyes],[ AC_MSG_CHECKING([for C compiler flags to error on warnings]) AC_CACHE_VAL(hts_cv_prog_cc_werror, [dnl hts_cv_prog_cc_werror="" AS_IF([test "x$CC" != "x"],[ cat > conftest.c < /dev/null 2>&1 && test -f conftest.o],[hts_cv_prog_cc_werror="-Werror"], # Sun Studio or Solaris C compiler ["$CC" -V 2>&1 | $GREP -i -E "WorkShop|Sun C" > /dev/null 2>&1 && "$CC" -c -errwarn=%all conftest.c > /dev/null 2>&1 && test -f conftest.o],[hts_cv_prog_cc_werror="-errwarn=%all"], # The Tiny C Compiler ["$CC" -v 2>&1 | $GREP "tcc version" > /dev/null && "$CC" -Wall -c conftest.c > /dev/null 2>&1 && test -f conftest.o],[hts_cv_prog_cc_werror="-Werror"] dnl TODO: Add more compilers ) rm -f conftest.* ]) ]) AS_IF([test "x$hts_cv_prog_cc_werror" != x],[ AC_MSG_RESULT($hts_cv_prog_cc_werror) AS_IF([test "x$1" != x],[eval AS_TR_SH([$1])="$hts_cv_prog_cc_werror"]) ],[dnl AC_MSG_RESULT(unknown) ]) ]) ])dnl HTS_PROG_CC_WERROR bcftools-1.21/main.c000066400000000000000000000233641467060157400143620ustar00rootroot00000000000000/* main.c -- main bcftools command front-end. Copyright (C) 2012-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include "config.h" #include #include #include #include #include #include #include "version.h" #include "bcftools.h" int main_tabix(int argc, char *argv[]); int main_vcfindex(int argc, char *argv[]); int main_vcfstats(int argc, char *argv[]); int main_vcfisec(int argc, char *argv[]); int main_vcfmerge(int argc, char *argv[]); int main_vcfquery(int argc, char *argv[]); int main_vcffilter(int argc, char *argv[]); int main_vcfsom(int argc, char *argv[]); int main_vcfnorm(int argc, char *argv[]); int main_vcfgtcheck(int argc, char *argv[]); int main_vcfview(int argc, char *argv[]); int main_vcfhead(int argc, char *argv[]); int main_vcfcall(int argc, char *argv[]); int main_vcfannotate(int argc, char *argv[]); int main_vcfroh(int argc, char *argv[]); int main_vcfconcat(int argc, char *argv[]); int main_reheader(int argc, char *argv[]); int main_vcfconvert(int argc, char *argv[]); int main_vcfcnv(int argc, char *argv[]); #if USE_GPL int main_polysomy(int argc, char *argv[]); #endif #ifdef ENABLE_BCF_PLUGINS int main_plugin(int argc, char *argv[]); int count_plugins(void); #endif int main_consensus(int argc, char *argv[]); int main_csq(int argc, char *argv[]); int main_mpileup(int argc, char *argv[]); int main_sort(int argc, char *argv[]); typedef struct { int (*func)(int, char*[]); const char *alias, *help; } cmd_t; static cmd_t cmds[] = { { .func = NULL, .alias = "Indexing", .help = NULL }, { .func = main_vcfindex, .alias = "index", .help = "index VCF/BCF files" }, { .func = main_tabix, .alias = "tabix", .help = "-tabix for BGZF'd BED, GFF, SAM, VCF and more" // do not advertise; only keep here for testing }, { .func = NULL, .alias = "VCF/BCF manipulation", .help = NULL }, { .func = main_vcfannotate, .alias = "annotate", .help = "annotate and edit VCF/BCF files", }, { .func = main_vcfconcat, .alias = "concat", .help = "concatenate VCF/BCF files from the same set of samples" }, { .func = main_vcfconvert, .alias = "convert", .help = "convert VCF/BCF files to different formats and back" }, { .func = main_vcfhead, .alias = "head", .help = "view VCF/BCF file headers" }, { .func = main_vcfisec, .alias = "isec", .help = "intersections of VCF/BCF files" }, { .func = main_vcfmerge, .alias = "merge", .help = "merge VCF/BCF files files from non-overlapping sample sets" }, { .func = main_vcfnorm, .alias = "norm", .help = "left-align and normalize indels" }, #ifdef ENABLE_BCF_PLUGINS { .func = main_plugin, .alias = "plugin", .help = "user-defined plugins" }, #endif { .func = main_vcfquery, .alias = "query", .help = "transform VCF/BCF into user-defined formats" }, { .func = main_reheader, .alias = "reheader", .help = "modify VCF/BCF header, change sample names" }, { .func = main_sort, .alias = "sort", .help = "sort VCF/BCF file" }, { .func = main_vcfview, .alias = "view", .help = "VCF/BCF conversion, view, subset and filter VCF/BCF files" }, { .func = NULL, .alias = "VCF/BCF analysis", .help = NULL }, { .func = main_vcfcall, .alias = "call", .help = "SNP/indel calling" }, { .func = main_consensus, .alias = "consensus", .help = "create consensus sequence by applying VCF variants" }, { .func = main_vcfcnv, .alias = "cnv", .help = "HMM CNV calling" }, { .func = main_csq, .alias = "csq", .help = "call variation consequences" }, { .func = main_vcffilter, .alias = "filter", .help = "filter VCF/BCF files using fixed thresholds" }, { .func = main_vcfgtcheck, .alias = "gtcheck", .help = "check sample concordance, detect sample swaps and contamination" }, { .func = main_mpileup, .alias = "mpileup", .help = "multi-way pileup producing genotype likelihoods" }, #if USE_GPL { .func = main_polysomy, .alias = "polysomy", .help = "detect number of chromosomal copies", }, #endif { .func = main_vcfroh, .alias = "roh", .help = "identify runs of autozygosity (HMM)", }, { .func = main_vcfstats, .alias = "stats", .help = "produce VCF/BCF stats" }, { .func = main_vcfsom, .alias = "som", .help = "-filter using Self-Organized Maps (experimental)" // do not advertise }, { .func = NULL, .alias = NULL, .help = NULL } }; char *bcftools_version(void) { return BCFTOOLS_VERSION; } static void usage(FILE *fp) { fprintf(fp, "\n"); fprintf(fp, "Program: bcftools (Tools for variant calling and manipulating VCFs and BCFs)\n"); #if USE_GPL fprintf(fp, "License: GNU GPLv3+, due to use of the GNU Scientific Library\n"); #endif fprintf(fp, "Version: %s (using htslib %s)\n", bcftools_version(), hts_version()); fprintf(fp, "\n"); fprintf(fp, "Usage: bcftools [--version|--version-only] [--help] \n"); fprintf(fp, "\n"); fprintf(fp, "Commands:\n"); int i = 0; const char *sep = NULL; while (cmds[i].alias) { if ( !cmds[i].func ) sep = cmds[i].alias; if ( sep ) { fprintf(fp, "\n -- %s\n", sep); sep = NULL; } if ( cmds[i].func && cmds[i].help[0]!='-' ) fprintf(fp, " %-12s %s\n", cmds[i].alias, cmds[i].help); i++; } #if ENABLE_BCF_PLUGINS fprintf(fp,"\n -- Plugins (collection of programs for calling, file manipulation & analysis)\n"); int nplugins = count_plugins(); if ( nplugins ) fprintf(fp," %d plugins available, run \"bcftools plugin -lv\" to see a complete list\n", nplugins); else fprintf(fp," 0 plugins available, run \"bcftools plugin -l\" for help\n"); #endif fprintf(fp,"\n"); fprintf(fp, " Most commands accept VCF, bgzipped VCF, and BCF with the file type detected\n" " automatically even when streaming from a pipe. Indexed VCF and BCF will work\n" " in all situations. Un-indexed VCF and BCF and streams will work in most but\n" " not all situations.\n"); fprintf(fp,"\n"); } // This is a tricky one, but on Windows the filename wildcard expansion is done by // the application and not by the shell, as traditionally it never had a "shell". // Even now, DOS and Powershell do not do this expansion (but bash does). // // This means that Mingw/Msys implements code before main() that takes e.g. "*" and // expands it up to a list of matching filenames. This in turn breaks things like // specifying "*" as a region (all the unmapped reads). We take a hard line here - // filename expansion is the task of the shell, not our application! #ifdef _WIN32 int _CRT_glob = 0; #endif int main(int argc, char *argv[]) { if (argc < 2) { usage(stderr); return 1; } if (strcmp(argv[1], "version") == 0 || strcmp(argv[1], "--version") == 0 || strcmp(argv[1], "-v") == 0) { printf("bcftools %s\nUsing htslib %s\nCopyright (C) 2024 Genome Research Ltd.\n", bcftools_version(), hts_version()); #if USE_GPL printf("License GPLv3+: GNU GPL version 3 or later \n"); #else printf("License Expat: The MIT/Expat license\n"); #endif printf("This is free software: you are free to change and redistribute it.\nThere is NO WARRANTY, to the extent permitted by law.\n"); return 0; } else if (strcmp(argv[1], "--version-only") == 0) { printf("%s+htslib-%s\n", bcftools_version(), hts_version()); return 0; } else if (strcmp(argv[1], "help") == 0 || strcmp(argv[1], "--help") == 0 || strcmp(argv[1], "-h") == 0) { if (argc == 2) { usage(stdout); return 0; } // Otherwise change "bcftools help COMMAND [...]" to "bcftools COMMAND"; // main_xyz() functions by convention display the subcommand's usage // when invoked without any arguments. argv++; argc = 2; } else if ( argv[1][0]=='+' ) { // "bcftools plugin name" can be run as "bcftools +name" argv[1]++; argv[0] = "plugin"; argv--; argc++; } int i = 0; while (cmds[i].alias) { if (cmds[i].func && strcmp(argv[1],cmds[i].alias)==0) { return cmds[i].func(argc-1,argv+1); } i++; } fprintf(stderr, "[E::%s] unrecognized command '%s'\n", __func__, argv[1]); return 1; } bcftools-1.21/mcall.c000066400000000000000000001771221467060157400145300ustar00rootroot00000000000000/* mcall.c -- multiallelic and rare variant calling. Copyright (C) 2012-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "call.h" #include "prob1.h" // Using priors for GTs does not seem to be mathematically justified. Although // it seems effective in removing false calls, it also flips a significant // proportion of HET genotypes. Better is to filter by FORMAT/GQ using // `bcftools filter`. #define USE_PRIOR_FOR_GTS 0 // Go with uniform PLs for samples with no coverage. If unset, missing // genotypes is reported instead. #define FLAT_PDG_FOR_MISSING 0 int test16(float *anno16, anno16_t *a); void qcall_init(call_t *call) { return; } void qcall_destroy(call_t *call) { return; } int qcall(call_t *call, bcf1_t *rec) { // QCall format: // chromosome, position, reference allele, depth, mapping quality, 0, .. error("TODO: qcall output\n"); return 0; } void call_init_pl2p(call_t *call) { int i; for (i=0; i<256; i++) call->pl2p[i] = pow(10., -i/10.); } // Macros for accessing call->trio and call->ntrio #define FTYPE_222 0 // family type: all diploid #define FTYPE_121 1 // chrX, the child is a boy #define FTYPE_122 2 // chrX, a girl #define FTYPE_101 3 // chrY, boy #define FTYPE_100 4 // chrY, girl #define GT_SKIP 0xf // empty genotype (chrY in females) #define IS_POW2(x) (!((x) & ((x) - 1))) // zero is permitted #define IS_HOM(x) IS_POW2(x) // Pkij = P(k|i,j) tells how likely it is to be a het if the parents // are homs etc. The consistency of i,j,k has been already checked. // Parameters are alleles and ploidy of father, mother, kid // Returns 2/Pkij. int calc_Pkij(int fals, int mals, int kals, int fpl, int mpl, int kpl) { int als = fals|mals|kals; if ( IS_HOM(als) ) return 2; // all are the same: child must be a HOM, P=1 if ( fpl==1 ) { if ( kpl==1 ) // chr X, the child is a boy, the copy is inherited from the mother { if ( IS_HOM(mals) ) return 2; // 0 11 -> P(1) = 1 return 4; // 0 01 -> P(0) = P(1) = 1/2 } // chr X, the child is a girl if ( IS_HOM(mals) ) return 2; // 0 11 -> P(01) = 1 return 4; // 0 01 -> P(00) = P(01) = 1/2 } if ( IS_HOM(fals) && IS_HOM(mals) ) return 2; // 00 11 01, the child must be a HET, P=1 if ( !IS_HOM(fals) && !IS_HOM(mals) ) { if ( IS_HOM(kals) ) return 8; // 01 01 00 or 01 01 11, P(k=HOM) = 1/4 return 4; // 01 01 01, P(k=HET) = 1/2 } return 4; // 00 01, P(k=HET) = P(k=HOM) = 1/2 } // Initialize ntrio and trio: ntrio lists the number of possible // genotypes given combination of haploid/diploid genomes and the // number of alleles. trio lists allowed genotype combinations: // 4bit: 2/Pkij, 4: father, 4: mother, 4: child // See also mcall_call_trio_genotypes() // static void mcall_init_trios(call_t *call) { if ( call->prior_AN ) { int id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,call->prior_AN); if ( id==-1 ) error("No such tag \"%s\"\n", call->prior_AN); if ( !bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,id) ) error("No such FORMAT tag \"%s\"\n", call->prior_AN); id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,call->prior_AC); if ( id==-1 ) error("No such tag \"%s\"\n", call->prior_AC); if ( !bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,id) ) error("No such FORMAT tag \"%s\"\n", call->prior_AC); } // 23, 138, 478 possible diploid trio genotypes with 2, 3, 4 alleles call->ntrio[FTYPE_222][2] = 15; call->ntrio[FTYPE_222][3] = 78; call->ntrio[FTYPE_222][4] = 250; call->ntrio[FTYPE_121][2] = 8; call->ntrio[FTYPE_121][3] = 27; call->ntrio[FTYPE_121][4] = 64; call->ntrio[FTYPE_122][2] = 8; call->ntrio[FTYPE_122][3] = 27; call->ntrio[FTYPE_122][4] = 64; call->ntrio[FTYPE_101][2] = 2; call->ntrio[FTYPE_101][3] = 3; call->ntrio[FTYPE_101][4] = 4; call->ntrio[FTYPE_100][2] = 2; call->ntrio[FTYPE_100][3] = 3; call->ntrio[FTYPE_100][4] = 4; int nals, itype; for (itype=0; itype<=4; itype++) { for (nals=2; nals<=4; nals++) call->trio[itype][nals] = (uint16_t*) malloc(sizeof(uint16_t)*call->ntrio[itype][nals]); } // max 10 possible diploid genotypes int gts[10]; for (nals=2; nals<=4; nals++) { int i,j,k, n = 0, ngts = 0; for (i=0; itrio[FTYPE_222][nals][n++] = Pkij<<12 | i<<8 | j<<4 | k; // father, mother, child } assert( n==call->ntrio[FTYPE_222][nals] ); // 121: chrX, boy n = 0; for (i=0; itrio[FTYPE_121][nals][n++] = Pkij<<12 | i<<8 | j<<4 | k; } assert( n==call->ntrio[FTYPE_121][nals] ); // 122: chrX, girl n = 0; for (i=0; itrio[FTYPE_122][nals][n++] = Pkij<<12 | i<<8 | j<<4 | k; } assert( n==call->ntrio[FTYPE_122][nals] ); // 101: chrY, boy n = 0; for (i=0; itrio[FTYPE_101][nals][n++] = 1<<12 | i<<8 | GT_SKIP<<4 | k; } assert( n==call->ntrio[FTYPE_101][nals] ); // 100: chrY, girl n = 0; for (i=0; itrio[FTYPE_100][nals][n++] = 1<<12 | i<<8 | GT_SKIP<<4 | GT_SKIP; } assert( n==call->ntrio[FTYPE_100][nals] ); } call->GLs = (double*) calloc(bcf_hdr_nsamples(call->hdr)*10,sizeof(double)); int i, j; for (i=0; infams; i++) { family_t *fam = &call->fams[i]; int ploidy[3]; for (j=0; j<3; j++) ploidy[j] = call->ploidy[fam->sample[j]]; if ( ploidy[FATHER]==2 ) // not X, not Y { if ( ploidy[MOTHER]!=2 || ploidy[CHILD]!=2 ) error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); fam->type = FTYPE_222; continue; } if ( ploidy[FATHER]!=1 || ploidy[MOTHER]==1 ) error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); if ( ploidy[MOTHER]==2 ) // X { if ( ploidy[CHILD]==0 ) error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); fam->type = ploidy[CHILD]==2 ? FTYPE_122 : FTYPE_121; // a girl or a boy } else // Y { if ( ploidy[CHILD]==2 ) error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); fam->type = ploidy[CHILD]==0 ? FTYPE_100 : FTYPE_101; // a girl or a boy } } } static void mcall_destroy_trios(call_t *call) { int i, j; for (i=2; i<=4; i++) for (j=0; j<=4; j++) free(call->trio[j][i]); } static void init_sample_groups(call_t *call) { int i, nsmpl = bcf_hdr_nsamples(call->hdr); if ( !call->sample_groups ) { // standard pooled calling, all samples in the same group call->nsmpl_grp = 1; call->smpl_grp = (smpl_grp_t*)calloc(1,sizeof(*call->smpl_grp)); call->smpl_grp[0].nsmpl = nsmpl; call->smpl_grp[0].smpl = (uint32_t*)calloc(call->smpl_grp[0].nsmpl,sizeof(uint32_t)); for (i=0; ismpl_grp[0].smpl[i] = i; return; } if ( call->sample_groups_tag ) { // Is the tag defined in the header? int tag_id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,call->sample_groups_tag); if ( tag_id==-1 ) error("No such tag \"%s\"\n",call->sample_groups_tag); if ( !bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,tag_id) ) error("No such FORMAT tag \"%s\"\n", call->sample_groups_tag); } else { int tag_id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,"QS"); if ( tag_id >= 0 && bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,tag_id) ) call->sample_groups_tag = "QS"; else { tag_id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,"AD"); if ( tag_id >= 0 && bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,tag_id) ) call->sample_groups_tag = "AD"; else error("Error: neither \"AD\" nor \"QS\" FORMAT tag exists and no alternative given with -G\n"); } } // Read samples/groups if ( !strcmp("-",call->sample_groups) ) { // single-sample calling, each sample creates its own group call->nsmpl_grp = nsmpl; call->smpl_grp = (smpl_grp_t*)calloc(nsmpl,sizeof(*call->smpl_grp)); for (i=0; ismpl_grp[i].nsmpl = 1; call->smpl_grp[i].smpl = (uint32_t*)calloc(call->smpl_grp[i].nsmpl,sizeof(uint32_t)); call->smpl_grp[i].smpl[0] = i; } } else { int nlines; char **lines = hts_readlist(call->sample_groups, 1, &nlines); if ( !lines ) error("Could not read the file: %s\n", call->sample_groups); uint32_t *smpl2grp = (uint32_t*)calloc(nsmpl,sizeof(uint32_t)); uint32_t *grp2n = (uint32_t*)calloc(nsmpl,sizeof(uint32_t)); void *grp2idx = khash_str2int_init(); call->nsmpl_grp = 0; for (i=0; isample_groups,lines[i]); char *tmp = ptr; while ( *ptr && isspace(*ptr) ) ptr++; if ( !*ptr ) error("Could not parse the line in %s, expected a sample name followed by tab and a population name: %s\n",call->sample_groups,lines[i]); *tmp = 0; int ismpl = bcf_hdr_id2int(call->hdr, BCF_DT_SAMPLE, lines[i]); if ( ismpl<0 ) continue; if ( smpl2grp[ismpl] ) error("Error: the sample \"%s\" is listed twice in %s\n", lines[i],call->sample_groups); if ( !khash_str2int_has_key(grp2idx,ptr+1) ) { khash_str2int_set(grp2idx, ptr+1, call->nsmpl_grp); call->nsmpl_grp++; } int igrp = -1; if ( khash_str2int_get(grp2idx, ptr+1, &igrp)!=0 ) error("This should not happen, fixme: %s\n",ptr+1); grp2n[igrp]++; smpl2grp[ismpl] = igrp+1; // +1 to distinguish unlisted samples } khash_str2int_destroy(grp2idx); if ( !call->nsmpl_grp ) error("Could not parse the file, no matching samples found: %s\n", call->sample_groups); call->smpl_grp = (smpl_grp_t*)calloc(call->nsmpl_grp,sizeof(*call->smpl_grp)); for (i=0; ihdr->samples[i],call->sample_groups); int igrp = smpl2grp[i] - 1; if ( !call->smpl_grp[igrp].nsmpl ) call->smpl_grp[igrp].smpl = (uint32_t*)calloc(grp2n[igrp],sizeof(uint32_t)); call->smpl_grp[igrp].smpl[call->smpl_grp[igrp].nsmpl] = i; call->smpl_grp[igrp].nsmpl++; } free(smpl2grp); free(grp2n); for (i=0; insmpl_grp; i++) { free(call->smpl_grp[i].qsum); free(call->smpl_grp[i].smpl); } free(call->smpl_grp); } void mcall_init(call_t *call) { init_sample_groups(call); call_init_pl2p(call); call->nals_map = 5; call->als_map = (int*) malloc(sizeof(int)*call->nals_map); call->npl_map = 5*(5+1)/2; // will be expanded later if necessary call->pl_map = (int*) malloc(sizeof(int)*call->npl_map); call->gts = (int32_t*) calloc(bcf_hdr_nsamples(call->hdr)*2,sizeof(int32_t)); // assuming at most diploid everywhere if ( call->flag & CALL_CONSTR_TRIO ) { call->cgts = (int32_t*) calloc(bcf_hdr_nsamples(call->hdr),sizeof(int32_t)); call->ugts = (int32_t*) calloc(bcf_hdr_nsamples(call->hdr),sizeof(int32_t)); mcall_init_trios(call); bcf_hdr_append(call->hdr,"##FORMAT="); bcf_hdr_append(call->hdr,"##FORMAT="); } if ( call->flag & CALL_CONSTR_ALLELES ) call->vcmp = vcmp_init(); bcf_hdr_append(call->hdr,"##FORMAT="); if ( call->output_tags & CALL_FMT_GQ ) bcf_hdr_append(call->hdr,"##FORMAT="); if ( call->output_tags & CALL_FMT_GP ) bcf_hdr_append(call->hdr,"##FORMAT="); if ( call->output_tags & (CALL_FMT_GQ|CALL_FMT_GP) ) call->GQs = (int32_t*) malloc(sizeof(int32_t)*bcf_hdr_nsamples(call->hdr)); bcf_hdr_append(call->hdr,"##INFO="); bcf_hdr_append(call->hdr,"##INFO="); bcf_hdr_append(call->hdr,"##INFO="); bcf_hdr_append(call->hdr,"##INFO="); if ( call->output_tags & CALL_FMT_PV4 ) bcf_hdr_append(call->hdr,"##INFO=\n"); // init the prior if ( call->theta>0 ) { int i, n = 0; if ( !call->ploidy ) n = 2*bcf_hdr_nsamples(call->hdr); // all are diploid else { for (i=0; ihdr); i++) n += call->ploidy[i]; } // Watterson factor, here aM_1 = aM_2 = 1 double aM = 1; for (i=2; itheta *= aM; if ( call->theta >= 1 ) { fprintf(stderr,"The prior is too big (theta*aM=%.2f), going with 0.99\n", call->theta); call->theta = 0.99; } call->theta = log(call->theta); } } void mcall_destroy(call_t *call) { destroy_sample_groups(call); if (call->vcmp) vcmp_destroy(call->vcmp); free(call->itmp); mcall_destroy_trios(call); free(call->GPs); free(call->ADs); free(call->GLs); free(call->GQs); free(call->anno16); free(call->PLs); free(call->als_map); free(call->pl_map); free(call->gts); free(call->cgts); free(call->ugts); free(call->pdg); free(call->als); free(call->ac); return; } // Inits P(D|G): convert PLs from log space and normalize. In case of zero // depth, missing PLs are all zero. In this case, pdg's are set to 0 // so that the corresponding genotypes can be set as missing and the // qual calculation is not affected. // Missing values are replaced by generic likelihoods when X (unseen allele) is // present. // NB: While the -m calling model uses the pdgs in canonical order, // the original samtools -c calling code uses pdgs in reverse order (AA comes // first, RR last). // NB: Ploidy is not taken into account here, which is incorrect. void set_pdg(double *pl2p, int *PLs, double *pdg, int n_smpl, int n_gt, int unseen) { int i, j, nals; // find out the number of alleles, expecting diploid genotype likelihoods bcf_gt2alleles(n_gt-1, &i, &nals); assert( i==nals ); nals++; for (i=0; i new(j) for (i=0; ials_map[i] = nout++; else call->als_map[i] = -1; } if ( !call->pl_map ) return; // pl_map: new(k) -> old(l) int k = 0, l = 0; for (i=0; ipl_map[k++] = l; l++; } } } /** log(exp(a)+exp(b)) */ static inline double logsumexp2(double a, double b) { if ( a>b ) return log(1 + exp(b-a)) + a; else return log(1 + exp(a-b)) + b; } // Macro to set the most likely alleles #define UPDATE_MAX_LKs(als,sum) { \ if ( max_lknsmpl; int ngts = nals*(nals+1)/2; // Single allele for (ia=0; iapdg + grp->smpl[ismpl]*ngts + iaa; if ( *pdg ) { lk_tot += log(*pdg); lk_tot_set = 1; } } if ( ia==0 ) ref_lk = lk_tot; // likelihood of 0/0 for all samples else lk_tot += call->theta; // the prior UPDATE_MAX_LKs(1<0 && lk_tot_set); } // Two alleles if ( nals>1 ) { for (ia=0; iaqsum[ia]==0 ) continue; int iaa = (ia+1)*(ia+2)/2-1; for (ib=0; ibqsum[ib]==0 ) continue; double lk_tot = 0; int lk_tot_set = 0; double fa = grp->qsum[ia]/(grp->qsum[ia] + grp->qsum[ib]); double fb = grp->qsum[ib]/(grp->qsum[ia] + grp->qsum[ib]); double fa2 = fa*fa; double fb2 = fb*fb; double fab = 2*fa*fb; int is, ibb = (ib+1)*(ib+2)/2-1, iab = iaa - ia + ib; for (is=0; issmpl[is]; double *pdg = call->pdg + ismpl*ngts; double val = 0; if ( !call->ploidy || call->ploidy[ismpl]==2 ) val = fa2*pdg[iaa] + fb2*pdg[ibb] + fab*pdg[iab]; else if ( call->ploidy && call->ploidy[ismpl]==1 ) val = fa*pdg[iaa] + fb*pdg[ibb]; if ( val ) { lk_tot += log(val); lk_tot_set = 1; } } if ( ia!=0 ) lk_tot += call->theta; // the prior if ( ib!=0 ) lk_tot += call->theta; UPDATE_MAX_LKs(1<2 ) { for (ia=0; iaqsum[ia]==0 ) continue; int iaa = (ia+1)*(ia+2)/2-1; for (ib=0; ibqsum[ib]==0 ) continue; int ibb = (ib+1)*(ib+2)/2-1; int iab = iaa - ia + ib; for (ic=0; icqsum[ic]==0 ) continue; double lk_tot = 0; int lk_tot_set = 0; double fa = grp->qsum[ia]/(grp->qsum[ia] + grp->qsum[ib] + grp->qsum[ic]); double fb = grp->qsum[ib]/(grp->qsum[ia] + grp->qsum[ib] + grp->qsum[ic]); double fc = grp->qsum[ic]/(grp->qsum[ia] + grp->qsum[ib] + grp->qsum[ic]); double fa2 = fa*fa; double fb2 = fb*fb; double fc2 = fc*fc; double fab = 2*fa*fb, fac = 2*fa*fc, fbc = 2*fb*fc; int is, icc = (ic+1)*(ic+2)/2-1; int iac = iaa - ia + ic, ibc = ibb - ib + ic; for (is=0; issmpl[is]; double *pdg = call->pdg + ismpl*ngts; double val = 0; if ( !call->ploidy || call->ploidy[ismpl]==2 ) val = fa2*pdg[iaa] + fb2*pdg[ibb] + fc2*pdg[icc] + fab*pdg[iab] + fac*pdg[iac] + fbc*pdg[ibc]; else if ( call->ploidy && call->ploidy[ismpl]==1 ) val = fa*pdg[iaa] + fb*pdg[ibb] + fc*pdg[icc]; if ( val ) { lk_tot += log(val); lk_tot_set = 1; } } if ( ia!=0 ) lk_tot += call->theta; // the prior if ( ib!=0 ) lk_tot += call->theta; // the prior if ( ic!=0 ) lk_tot += call->theta; // the prior UPDATE_MAX_LKs(1<max_lk = max_lk; grp->ref_lk = ref_lk; grp->lk_sum = lk_sum; grp->als = max_als; grp->nals = n; return n; } // Sets GT=0/0 or GT=. if PL=0,0,0 static void mcall_set_ref_genotypes(call_t *call, int nals_ori) { int i; int ngts = nals_ori*(nals_ori+1)/2; // need this to distinguish between GT=0/0 vs GT=. int nsmpl = bcf_hdr_nsamples(call->hdr); for (i=0; iac[i] = 0; // nals_new<=nals_ori, never mind setting extra 0's // Set all genotypes to 0/0 or 0 int *gts = call->gts; double *pdg = call->pdg; int isample; for (isample = 0; isample < nsmpl; isample++) { int ploidy = call->ploidy ? call->ploidy[isample] : 2; for (i=0; iac[0] += ploidy; } gts += 2; pdg += ngts; } } static void mcall_call_genotypes(call_t *call, int nals_ori, smpl_grp_t *grp) { int ia, ib, i; int ngts_ori = nals_ori*(nals_ori+1)/2; int ngts_new = call->nals_new*(call->nals_new+1)/2; int nsmpl = grp->nsmpl; #if USE_PRIOR_FOR_GTS float prior = exp(call->theta); #endif int is; for (is = 0; is < nsmpl; is++) { int ismpl = grp->smpl[is]; double *pdg = call->pdg + ismpl*ngts_ori; float *gps = call->GPs + ismpl*ngts_new; int *gts = call->gts + ismpl*2; int ploidy = call->ploidy ? call->ploidy[ismpl] : 2; assert( ploidy>=0 && ploidy<=2 ); if ( !ploidy ) { gts[0] = bcf_gt_missing; gts[1] = bcf_int32_vector_end; gps[0] = -1; continue; } #if !FLAT_PDG_FOR_MISSING // Skip samples with zero depth, they have all pdg's equal to 0 for (i=0; ials & 1<qsum[ia]*grp->qsum[ia] : pdg[iaa]*grp->qsum[ia]; #if USE_PRIOR_FOR_GTS if ( ia!=0 ) lk *= prior; #endif int igt = ploidy==2 ? bcf_alleles2gt(call->als_map[ia],call->als_map[ia]) : call->als_map[ia]; gps[igt] = lk; if ( best_lk < lk ) { best_lk = lk; gts[0] = bcf_gt_unphased(call->als_map[ia]); } } if ( ploidy==2 ) { gts[1] = gts[0]; for (ia=0; iaals & 1<als & 1<qsum[ia]*grp->qsum[ib]; #if USE_PRIOR_FOR_GTS if ( ia!=0 ) lk *= prior; if ( ib!=0 ) lk *= prior; #endif int igt = bcf_alleles2gt(call->als_map[ia],call->als_map[ib]); gps[igt] = lk; if ( best_lk < lk ) { best_lk = lk; gts[0] = bcf_gt_unphased(call->als_map[ib]); gts[1] = bcf_gt_unphased(call->als_map[ia]); } } } } else gts[1] = bcf_int32_vector_end; call->ac[ bcf_gt_allele(gts[0]) ]++; if ( gts[1]!=bcf_int32_vector_end ) call->ac[ bcf_gt_allele(gts[1]) ]++; } if ( !(call->output_tags & (CALL_FMT_GQ|CALL_FMT_GP)) ) return; double max, sum; for (is=0; issmpl[is]; float *gps = call->GPs + ismpl*ngts_new; int nmax; if ( call->ploidy ) { if ( call->ploidy[ismpl]==2 ) nmax = ngts_new; else if ( call->ploidy[ismpl]==1 ) nmax = grp->nals; else nmax = 0; } else nmax = ngts_new; max = gps[0]; if ( max<0 || nmax==0 ) { // no call if ( call->output_tags & CALL_FMT_GP ) { for (i=0; iGQs[ismpl] = 0; continue; } sum = gps[0]; for (i=1; iGQs[ismpl] = max<=INT8_MAX ? max : INT8_MAX; if ( call->output_tags & CALL_FMT_GP ) { assert( max ); for (i=0; ihdr); int ngts = nals*(nals+1)/2; int nout_gts = nals_new*(nals_new+1)/2; double *gls = call->GLs - nout_gts; double *pdg = call->pdg - ngts; // Calculate individuals' genotype likelihoods P(X=i) int isample; for (isample = 0; isample < nsmpl; isample++) { int ploidy = call->ploidy ? call->ploidy[isample] : 2; int32_t *gts = call->ugts + isample; gls += nout_gts; pdg += ngts; // Skip samples with all pdg's equal to 1. These have zero depth. for (i=0; ismpl_grp.grp[call->smpl_grp.smpl2grp[isample]]; double sum_lk = 0; double best_lk = 0; for (ia=0; iaals_map[ia],call->als_map[ia]); double lk = ploidy==2 ? pdg[iaa]*grp->qsum[ia]*grp->qsum[ia] : pdg[iaa]*grp->qsum[ia]; sum_lk += lk; gls[idx] = lk; if ( best_lk < lk ) { best_lk = lk; gts[0] = bcf_alleles2gt(call->als_map[ia],call->als_map[ia]); } } if ( ploidy==2 ) { for (ia=0; iaals_map[ia],call->als_map[ib]); double lk = 2*pdg[iab]*grp->qsum[ia]*grp->qsum[ib]; sum_lk += lk; gls[idx] = lk; if ( best_lk < lk ) { best_lk = lk; gts[0] = bcf_alleles2gt(call->als_map[ib],call->als_map[ia]); } } } } for (i=0; itrio_Pm_ins<0 && call->trio_Pm_del<0 ) trio_Pm = call->trio_Pm_SNPs; // the same Pm for indels and SNPs requested else { int ret = bcf_get_variant_types(rec); if ( !(ret & VCF_INDEL) ) trio_Pm = call->trio_Pm_SNPs; else { if ( call->trio_Pm_ins<0 ) // dynamic calculation, trio_Pm_del holds the scaling factor { trio_Pm = rec->d.var[1].n<0 ? -21.9313 - 0.2856*rec->d.var[1].n : -22.8689 + 0.2994*rec->d.var[1].n; trio_Pm = 1 - call->trio_Pm_del * exp(trio_Pm); } else // snps and indels set explicitly { trio_Pm = rec->d.var[1].n<0 ? call->trio_Pm_del : call->trio_Pm_ins; } } } // Calculate constrained likelihoods and determine genotypes int ifm; for (ifm=0; ifmnfams; ifm++) { family_t *fam = &call->fams[ifm]; int ntrio = call->ntrio[fam->type][nals_new]; uint16_t *trio = call->trio[fam->type][nals_new]; // Unconstrained likelihood int uc_itr = 0; double uc_lk = 0; for (i=0; i<3; i++) // for father, mother, child { int ismpl = fam->sample[i]; double *gl = call->GLs + nout_gts*ismpl; if ( gl[0]==1 ) continue; int j, jmax = 0; double max = gl[0]; for (j=1; jsample[i]; double *gl = call->GLs + nout_gts*ismpl; if ( gl[0]==1 ) continue; int igt = trio[itr]>>((2-i)*4) & 0xf; assert( !call->ploidy || call->ploidy[ismpl]>0 ); if ( igt==GT_SKIP ) continue; lk += gl[igt]; npresent++; // fprintf(stderr," %e", gl[igt]); } // fprintf(stderr,"\t\t"); double Pkij = npresent==3 ? (double)2/(trio[itr]>>12) : 1; // with missing genotypes Pkij's are different lk += log(1 - trio_Pm * (1 - Pkij)); // fprintf(stderr,"%d%d%d\t%e\t%.2f\n", trio[itr]>>8&0xf,trio[itr]>>4&0xf,trio[itr]&0xf, lk, Pkij); if ( c_lk < lk ) { c_lk = lk; c_itr = trio[itr]; } if ( uc_itr==trio[itr] ) uc_is_mendelian = 1; } if ( !uc_is_mendelian ) { uc_lk += log(1 - trio_Pm); // fprintf(stderr,"c_lk=%e uc_lk=%e c_itr=%d%d%d uc_itr=%d%d%d\n", c_lk,uc_lk,c_itr>>8&0xf,c_itr>>4&0xf,c_itr&0xf,uc_itr>>8&0xf,uc_itr>>4&0xf,uc_itr&0xf); if ( c_lk < uc_lk ) { c_lk = uc_lk; c_itr = uc_itr; } } // fprintf(stderr,"best_lk=%e best_itr=%d%d%d uc_itr=%d%d%d\n", c_lk,c_itr>>8&0xf,c_itr>>4&0xf,c_itr&0xf,uc_itr>>8&0xf,uc_itr>>4&0xf,uc_itr&0xf); // Set genotypes for father, mother, child and calculate genotype qualities for (i=0; i<3; i++) { // GT int ismpl = fam->sample[i]; int igt = c_itr>>((2-i)*4) & 0xf; double *gl = call->GLs + nout_gts*ismpl; int32_t *gts = call->cgts + ismpl; if ( gl[0]==1 || igt==GT_SKIP ) // zero depth, set missing genotypes { gts[0] = -1; // bcf_float_set_missing(call->GQs[ismpl]); continue; } gts[0] = igt; #if 0 // todo: Genotype Qualities // // GQ: for each family member i sum over all genotypes j,k keeping igt fixed double lk_sum = 0; for (itr=0; itr>((2-i)*4) & 0xf) ) continue; double lk = 0; int j; for (j=0; j<3; j++) { int jsmpl = fam->sample[j]; double *gl = call->GLs + ngts*jsmpl; if ( gl[0]==1 ) continue; int jgt = trio[itr]>>((2-j)*4) & 0xf; if ( jgt==GT_SKIP ) continue; lk += gl[jgt]; } double Pkij = (double)2/(trio[itr]>>12); lk += log(1 - trio_Pm * (1 - Pkij)); lk_sum = logsumexp2(lk_sum, lk); } if ( !uc_is_mendelian && (best_itr>>((2-i)*4)&0xf)==(uc_itr>>((2-i)*4)&0xf) ) lk_sum = logsumexp2(lk_sum,uc_lk); call->GQs[ismpl] = -4.3429*(best_lk - lk_sum); #endif } } for (i=0; i<4; i++) call->ac[i] = 0; call->nhets = 0; call->ndiploid = 0; // Test if CGT,UGT are needed int ucgts_needed = 0; int32_t *cgts = call->cgts - 1; int32_t *ugts = call->ugts - 1; int32_t *gts = call->gts - 2; for (isample = 0; isample < nsmpl; isample++) { int ploidy = call->ploidy ? call->ploidy[isample] : 2; cgts++; ugts++; gts += 2; if ( ugts[0]==-1 ) { gts[0] = bcf_gt_missing; gts[1] = ploidy==2 ? bcf_gt_missing : bcf_int32_vector_end; continue; } int a,b; if ( cgts[0]!=ugts[0] ) { bcf_gt2alleles(cgts[0], &a, &b); gts[0] = bcf_gt_unphased(a); gts[1] = ploidy==1 ? bcf_int32_vector_end : bcf_gt_unphased(b); } else { bcf_gt2alleles(ugts[0], &a, &b); gts[0] = bcf_gt_unphased(a); gts[1] = ploidy==1 ? bcf_int32_vector_end : bcf_gt_unphased(b); } if ( cgts[0]!=ugts[0] ) ucgts_needed = 1; call->ac[a]++; if ( ploidy==2 ) { call->ac[b]++; call->ndiploid++; if ( a!=b ) call->nhets++; } } if ( ucgts_needed ) { // Some GTs are different bcf_update_format_int32(call->hdr,rec,"UGT",call->ugts,nsmpl); bcf_update_format_int32(call->hdr,rec,"CGT",call->cgts,nsmpl); } } #endif static void mcall_trim_and_update_PLs(call_t *call, bcf1_t *rec, int nals_ori, int nals_new) { int npls_src = nals_ori*(nals_ori+1)/2; int npls_dst = nals_new*(nals_new+1)/2; // number of PL values in diploid samples, ori and new if ( call->all_diploid && npls_src == npls_dst ) return; int *pls_src = call->PLs, *pls_dst = call->PLs; int nsmpl = bcf_hdr_nsamples(call->hdr); int isample, ia; for (isample = 0; isample < nsmpl; isample++) { int ploidy = call->ploidy ? call->ploidy[isample] : 2; if ( ploidy==2 ) { for (ia=0; iapl_map[ia] ]; } else if ( ploidy==1 ) { for (ia=0; iapl_map[isrc] ]; } if ( ia1 in mcall() } pls_src += npls_src; pls_dst += npls_dst; } bcf_update_format_int32(call->hdr, rec, "PL", call->PLs, npls_dst*nsmpl); } void mcall_trim_and_update_numberR(call_t *call, bcf1_t *rec, int nals_ori, int nals_new) { if ( nals_ori==nals_new ) return; int i,j, nret, size = sizeof(float); void *tmp_ori = call->itmp, *tmp_new = call->PLs; // reusing PLs storage which is not used at this point int ntmp_ori = call->n_itmp, ntmp_new = call->mPLs; // INFO fields for (i=0; in_info; i++) { bcf_info_t *info = &rec->d.info[i]; int vlen = bcf_hdr_id2length(call->hdr,BCF_HL_INFO,info->key); if ( vlen!=BCF_VL_R ) continue; // not a Number=R tag int type = bcf_hdr_id2type(call->hdr,BCF_HL_INFO,info->key); const char *key = bcf_hdr_int2id(call->hdr,BCF_DT_ID,info->key); nret = bcf_get_info_values(call->hdr, rec, key, &tmp_ori, &ntmp_ori, type); if ( nret<=0 ) continue; if ( nals_new==1 ) bcf_update_info_int32(call->hdr, rec, key, tmp_ori, 1); // has to be the REF, the order could not change else { for (j=0; jals_map[j]; if ( k==-1 ) continue; // to be dropped memcpy((char *)tmp_new+size*k, (char *)tmp_ori+size*j, size); } bcf_update_info_int32(call->hdr, rec, key, tmp_new, nals_new); } } // FORMAT fields for (i=0; in_fmt; i++) { bcf_fmt_t *fmt = &rec->d.fmt[i]; int vlen = bcf_hdr_id2length(call->hdr,BCF_HL_FMT,fmt->id); if ( vlen!=BCF_VL_R ) continue; // not a Number=R tag int type = bcf_hdr_id2type(call->hdr,BCF_HL_FMT,fmt->id); const char *key = bcf_hdr_int2id(call->hdr,BCF_DT_ID,fmt->id); nret = bcf_get_format_values(call->hdr, rec, key, &tmp_ori, &ntmp_ori, type); if (nret<=0) continue; int nsmpl = bcf_hdr_nsamples(call->hdr); assert( nret==nals_ori*nsmpl ); for (j=0; jals_map[k]; if ( l==-1 ) continue; // to be dropped memcpy(ptr_dst+size*l, ptr_src+size*k, size); } } bcf_update_format_int32(call->hdr, rec, key, tmp_new, nals_new*nsmpl); } call->PLs = (int32_t*) tmp_new; call->mPLs = ntmp_new; call->itmp = (int32_t*) tmp_ori; call->n_itmp = ntmp_ori; } // NB: in this function we temporarily use calls->als_map for a different // purpose to store mapping from new (target) alleles to original alleles. // static int mcall_constrain_alleles(call_t *call, bcf1_t *rec, int *unseen) { assert( call->tgt_als->n ); hts_expand(char*,call->tgt_als->n+1,call->nals,call->als); hts_expand(int,call->tgt_als->n+1,call->nals_map,call->als_map); hts_expand(int,(call->tgt_als->n+1)*(call->tgt_als->n+2)/2,call->npl_map,call->pl_map); int has_new = 0; int i, j, nals = 1; for (i=1; inals_map; i++) call->als_map[i] = -1; if ( vcmp_set_ref(call->vcmp, rec->d.allele[0], call->tgt_als->allele[0]) < 0 ) error("The reference alleles are not compatible at %s:%d .. %s vs %s\n", call->hdr->id[BCF_DT_CTG][rec->rid].key,rec->pos+1,call->tgt_als->allele[0],rec->d.allele[0]); // create mapping from new to old alleles call->als[0] = call->tgt_als->allele[0]; call->als_map[0] = 0; for (i=1; itgt_als->n; i++) { call->als[nals] = call->tgt_als->allele[i]; j = vcmp_find_allele(call->vcmp, rec->d.allele+1, rec->n_allele - 1, call->tgt_als->allele[i]); if ( j>=0 ) { // existing allele call->als_map[nals] = j+1; } else { // There is a new allele in targets which is not present in VCF. // We use the X allele to estimate PLs. Note that X may not be // present at multiallelic indels sites. In that case we use the // last allele anyway, because the least likely allele comes last // in mpileup's ALT output. call->als_map[nals] = (*unseen)>=0 ? *unseen : rec->n_allele - 1; has_new = 1; } nals++; } if ( *unseen ) { call->als_map[nals] = *unseen; call->als[nals] = rec->d.allele[*unseen]; nals++; } if ( !has_new && nals==rec->n_allele ) return 0; bcf_update_alleles(call->hdr, rec, (const char**)call->als, nals); // create mapping from new PL to old PL int k = 0; for (i=0; ials_map[i], b = call->als_map[j]; call->pl_map[k++] = a>b ? a*(a+1)/2 + b : b*(b+1)/2 + a; } } // update PL call->nPLs = bcf_get_format_int32(call->hdr, rec, "PL", &call->PLs, &call->mPLs); int nsmpl = bcf_hdr_nsamples(call->hdr); int npls_ori = call->nPLs / nsmpl; int npls_new = k; hts_expand(int32_t,npls_new*nsmpl,call->n_itmp,call->itmp); int *ori_pl = call->PLs, *new_pl = call->itmp; for (i=0; ipl_map[k]]; if ( new_pl[k]==bcf_int32_missing && *unseen>=0 ) { // missing value, and there is an unseen allele: identify the // alleles and use the lk of either AX or XX int k_ori = call->pl_map[k], ia, ib; bcf_gt2alleles(k_ori, &ia, &ib); k_ori = bcf_alleles2gt(ia,*unseen); if ( ori_pl[k_ori]==bcf_int32_missing ) k_ori = bcf_alleles2gt(ib,*unseen); if ( ori_pl[k_ori]==bcf_int32_missing ) k_ori = bcf_alleles2gt(*unseen,*unseen); new_pl[k] = ori_pl[k_ori]; } if ( !k && new_pl[k]==bcf_int32_vector_end ) new_pl[k]=bcf_int32_missing; } ori_pl += npls_ori; new_pl += npls_new; } bcf_update_format_int32(call->hdr, rec, "PL", call->itmp, npls_new*nsmpl); // update QS, use temporarily call->GPs to store the values int nqs = bcf_get_info_float(call->hdr, rec, "QS", &call->smpl_grp[0].qsum, &call->smpl_grp[0].nqsum); hts_expand(float,nals,call->nGPs,call->GPs); for (i=0; iGPs[i] = call->als_map[i]smpl_grp[0].qsum[call->als_map[i]] : 0; bcf_update_info_float(call->hdr, rec, "QS", call->GPs, nals); // update any Number=R tags void *tmp_ori = call->itmp, *tmp_new = call->PLs; // reusing PLs storage which is not used at this point int ntmp_ori = call->n_itmp, ntmp_new = call->mPLs; for (i=0; in_fmt; i++) { bcf_fmt_t *fmt = &rec->d.fmt[i]; int vlen = bcf_hdr_id2length(call->hdr,BCF_HL_FMT,fmt->id); if ( vlen!=BCF_VL_R ) continue; // not a Number=R tag // NB:works only for BCF_HT_INT and BCF_HT_REAL int type = bcf_hdr_id2type(call->hdr,BCF_HL_FMT,fmt->id); assert( type==BCF_HT_INT || type==BCF_HT_REAL ); assert( sizeof(float)==sizeof(int32_t) ); const char *key = bcf_hdr_int2id(call->hdr,BCF_DT_ID,fmt->id); int nret = bcf_get_format_values(call->hdr, rec, key, &tmp_ori, &ntmp_ori, type); if (nret<=0) continue; int nsmpl = bcf_hdr_nsamples(call->hdr); int size1 = sizeof(float); hts_expand(float, nsmpl * nals, ntmp_new, tmp_new); for (j=0; jn; uint8_t *ptr_new = (uint8_t *) tmp_new + j*nals*size1; for (k=0; kals_map[k]; memcpy(dst,src,size1); } } nret = bcf_update_format(call->hdr, rec, key, tmp_new, nsmpl*nals, type); assert( nret==0 ); } call->PLs = (int32_t*) tmp_new; call->mPLs = ntmp_new; call->itmp = (int32_t*) tmp_ori; call->n_itmp = ntmp_ori; if ( *unseen ) *unseen = nals-1; return 0; } /** * This function implements the multiallelic calling model. It has two major parts: * 1) determine the most likely set of alleles and calculate the quality of ref/non-ref site * 2) determine and set the genotypes * In various places in between, the BCF record gets updated. */ int mcall(call_t *call, bcf1_t *rec) { int i,j, unseen = call->unseen; // Force alleles when calling genotypes given alleles was requested if ( call->flag & CALL_CONSTR_ALLELES && mcall_constrain_alleles(call, rec, &unseen)!=0 ) return -2; int nsmpl = bcf_hdr_nsamples(call->hdr); int nals_ori = rec->n_allele; hts_expand(int,nals_ori,call->nac,call->ac); hts_expand(int,nals_ori,call->nals_map,call->als_map); hts_expand(int,nals_ori*(nals_ori+1)/2,call->npl_map,call->pl_map); // Get the genotype likelihoods call->nPLs = bcf_get_format_int32(call->hdr, rec, "PL", &call->PLs, &call->mPLs); if ( call->nPLs!=nsmpl*nals_ori*(nals_ori+1)/2 && call->nPLs!=nsmpl*nals_ori ) // a mixture of diploid and haploid or haploid only error("Wrong number of PL fields? nals=%d npl=%d\n", nals_ori,call->nPLs); // Convert PLs to probabilities int ngts_ori = nals_ori*(nals_ori+1)/2; hts_expand(double, call->nPLs, call->npdg, call->pdg); set_pdg(call->pl2p, call->PLs, call->pdg, nsmpl, ngts_ori, unseen); // Get sum of qualities, serves as an AF estimate, f_x = QS/N in Eq. 1 in call-m math notes. if ( call->nsmpl_grp == 1 ) { int nqs = bcf_get_info_float(call->hdr, rec, "QS", &call->smpl_grp[0].qsum, &call->smpl_grp[0].nqsum); if ( nqs<=0 ) error("The QS annotation not present at %s:%d\n", bcf_seqname(call->hdr,rec),rec->pos+1); if ( nqs < nals_ori ) { // Some of the listed alleles do not have the corresponding QS field. This is // typically ref-only site with <*> in ALT. hts_expand(float,nals_ori,call->smpl_grp[0].nqsum,call->smpl_grp[0].qsum); for (i=nqs; ismpl_grp[0].qsum[i] = 0; } } else { for (j=0; jnsmpl_grp; j++) { hts_expand(float,nals_ori,call->smpl_grp[j].nqsum,call->smpl_grp[j].qsum); memset(call->smpl_grp[j].qsum, 0, sizeof(float)*nals_ori); } // Use FORMAT/AD or FORMAT/QS int nad = bcf_get_format_int32(call->hdr, rec, call->sample_groups_tag, &call->ADs, &call->nADs); if ( nad<1 ) error("Error: FORMAT/%s is required with the -G option, mpileup must be run with \"-a AD\" or \"-a QS\"\n",call->sample_groups_tag); nad /= bcf_hdr_nsamples(call->hdr); for (i=0; insmpl_grp; i++) { int is; smpl_grp_t *grp = &call->smpl_grp[i]; hts_expand(float,nals_ori,grp->nqsum,grp->qsum); for (j=0; jqsum[j] = 0; for (is=0; isnsmpl; is++) { int ismpl = grp->smpl[is]; int32_t *ptr = call->ADs + ismpl*nad; float sum = 0; for (j=0; jqsum[j] += ptr[j]/sum; } } } } } // If available, take into account reference panel AFs if ( call->prior_AN && bcf_get_info_int32(call->hdr, rec, call->prior_AN ,&call->ac, &call->nac)==1 ) { int an = call->ac[0]; // number of alleles total, proceed only if not zero; reuse call->ac if ( an > 0 && bcf_get_info_int32(call->hdr, rec, call->prior_AC ,&call->ac, &call->nac)==nals_ori-1 ) // number of ALT alleles { int ac0 = an; // this will become the number of REFs for (i=0; iac[i]==bcf_int32_vector_end ) break; if ( call->ac[i]==bcf_int32_missing ) continue; ac0 -= call->ac[i]; // here an*0.5 is the number of samples in the populatio and ac*0.5 is the AF weighted by the number of samples for (j=0; jnsmpl_grp; j++) call->smpl_grp[j].qsum[i+1] = (call->smpl_grp[j].qsum[i+1] + 0.5*call->ac[i]) / (call->smpl_grp[j].nsmpl + 0.5*an); } if ( ac0<0 ) error("Incorrect %s,%s values at %s:%d\n", call->prior_AN,call->prior_AC,bcf_seqname(call->hdr,rec),rec->pos+1); for (j=0; jnsmpl_grp; j++) call->smpl_grp[j].qsum[0] = (call->smpl_grp[j].qsum[0] + 0.5*ac0) / (call->smpl_grp[j].nsmpl + 0.5*an); } } // normalize so that QS sums to 1 for each group for (j=0; jnsmpl_grp; j++) { float sum = 0; for (i=0; ismpl_grp[j].qsum[i]; if ( sum ) for (i=0; ismpl_grp[j].qsum[i] /= sum; } bcf_update_info_int32(call->hdr, rec, "QS", NULL, 0); // remove QS tag if ( nals_ori > 8*sizeof(call->als_new) ) { fprintf(stderr,"Too many alleles at %s:%"PRId64", skipping.\n", bcf_seqname(call->hdr,rec),(int64_t) rec->pos+1); return 0; } // For each group find the best combination of alleles call->als_new = 0; double ref_lk = -HUGE_VAL, lk_sum = -HUGE_VAL, max_qual = -HUGE_VAL; for (j=0; jnsmpl_grp; j++) { smpl_grp_t *grp = &call->smpl_grp[j]; mcall_find_best_alleles(call, nals_ori, grp); call->als_new |= grp->als; if ( grp->max_lk==-HUGE_VAL ) continue; double qual = -4.343*(grp->ref_lk - logsumexp2(grp->lk_sum,grp->ref_lk)); if ( max_qual < qual ) { max_qual = qual; lk_sum = grp->lk_sum; ref_lk = grp->ref_lk; } } // Make sure the REF allele is always present if ( !(call->als_new&1) ) call->als_new |= 1; int is_variant = call->als_new==1 ? 0 : 1; if ( call->flag & CALL_VARONLY && !is_variant ) return 0; call->nals_new = 0; for (i=0; iflag&CALL_KEEP_UNSEEN) && i==unseen && call->nals_new==1 ) { call->nals_new++; call->als_new |= 1<0 && i==unseen ) continue; if ( call->flag & CALL_KEEPALT ) call->als_new |= 1<als_new & (1<nals_new++; } init_allele_trimming_maps(call,nals_ori,call->als_new); int nAC = 0; if ( call->als_new==1 ) // only REF allele on output { mcall_set_ref_genotypes(call,nals_ori); bcf_update_format_int32(call->hdr, rec, "PL", NULL, 0); // remove PL, useless now } else if ( !is_variant ) { mcall_set_ref_genotypes(call,nals_ori); // running with -A, prevent mcall_call_genotypes from putting some ALT back mcall_trim_and_update_PLs(call, rec, nals_ori, call->nals_new); } else { // The most likely set of alleles includes non-reference allele (or was enforced), call genotypes. // Note that it is a valid outcome if the called genotypes exclude some of the ALTs. int ngts_new = call->nals_new*(call->nals_new+1)/2; hts_expand(float,ngts_new*nsmpl,call->nGPs,call->GPs); for (i=0; inals_new; i++) call->ac[i] = 0; if ( call->flag & CALL_CONSTR_TRIO && call->nals_new>4 ) { fprintf(stderr,"Too many alleles at %s:%"PRId64", skipping.\n", bcf_seqname(call->hdr,rec),(int64_t) rec->pos+1); return 0; } if ( call->output_tags & (CALL_FMT_GQ|CALL_FMT_GP) ) { memset(call->GPs,0,nsmpl*ngts_new*sizeof(*call->GPs)); memset(call->GQs,0,nsmpl*sizeof(*call->GQs)); } for (i=0; insmpl_grp; i++) { if ( call->flag & CALL_CONSTR_TRIO ) error("todo: constrained trio calling temporarily disabled\n"); //mcall_call_trio_genotypes(call,rec,nals,&call->smpl_grp[i]); else mcall_call_genotypes(call,nals_ori,&call->smpl_grp[i]); } // Skip the site if all samples are 0/0. This can happen occasionally. for (i=1; inals_new; i++) nAC += call->ac[i]; if ( !nAC && call->flag & CALL_VARONLY ) return 0; if ( call->output_tags & CALL_FMT_GP ) bcf_update_format_float(call->hdr, rec, "GP", call->GPs, nsmpl*ngts_new); if ( call->output_tags & CALL_FMT_GQ ) bcf_update_format_int32(call->hdr, rec, "GQ", call->GQs, nsmpl); mcall_trim_and_update_PLs(call,rec,nals_ori,call->nals_new); } if ( nals_ori!=call->nals_new ) mcall_trim_and_update_numberR(call,rec,nals_ori,call->nals_new); // Set QUAL if ( nAC ) { // Quality of a variant site. fabs() to avoid negative zeros in VCF output when CALL_KEEPALT is set rec->qual = max_qual; } else { // Set the quality of a REF site if ( lk_sum!=-HUGE_VAL ) // no support from (high quality) reads, so QUAL=1-prior rec->qual = -4.343*(lk_sum - logsumexp2(lk_sum,ref_lk)); else if ( call->ac[0] ) rec->qual = call->theta ? -4.343*call->theta : 0; else bcf_float_set_missing(rec->qual); } // AC, AN if ( call->nals_new>1 ) bcf_update_info_int32(call->hdr, rec, "AC", call->ac+1, call->nals_new-1); nAC += call->ac[0]; bcf_update_info_int32(call->hdr, rec, "AN", &nAC, 1); // Remove unused alleles hts_expand(char*,call->nals_new,call->nals,call->als); for (i=0; ials_map[i]>=0 ) call->als[call->als_map[i]] = rec->d.allele[i]; bcf_update_alleles(call->hdr, rec, (const char**)call->als, call->nals_new); bcf_update_genotypes(call->hdr, rec, call->gts, nsmpl*2); // DP4 and PV4 tags if ( bcf_get_info_float(call->hdr, rec, "I16", &call->anno16, &call->n16)==16 ) { int32_t dp[4]; dp[0] = call->anno16[0]; dp[1] = call->anno16[1]; dp[2] = call->anno16[2]; dp[3] = call->anno16[3]; bcf_update_info_int32(call->hdr, rec, "DP4", dp, 4); int32_t mq = (call->anno16[8]+call->anno16[10])/(call->anno16[0]+call->anno16[1]+call->anno16[2]+call->anno16[3]); bcf_update_info_int32(call->hdr, rec, "MQ", &mq, 1); if ( call->output_tags & CALL_FMT_PV4 ) { anno16_t a; float tmpf[4]; int is_tested = test16(call->anno16, &a) >= 0 && a.is_tested ? 1 : 0; if ( is_tested ) { for (i=0; i<4; i++) tmpf[i] = a.p[i]; bcf_update_info_float(call->hdr, rec, "PV4", tmpf, 4); } } } bcf_update_info_int32(call->hdr, rec, "I16", NULL, 0); // remove I16 tag return is_variant ? call->nals_new : 1; } bcftools-1.21/misc/000077500000000000000000000000001467060157400142155ustar00rootroot00000000000000bcftools-1.21/misc/color-chrs.pl000077500000000000000000000410711467060157400166330ustar00rootroot00000000000000#!/usr/bin/env perl # # Copyright (C) 2015, 2017 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. use strict; use warnings; use Carp; my $opts = parse_params(); chr_dims($opts); for my $file (@{$$opts{files}}) { read_dat($opts,$file); } merge_regs($opts); plot($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "About: Plot output of \"bcftools +color-chrs\"\n", "Usage: color-chrs.pl [OPTIONS] output.dat\n", "Options:\n", " -c, --colors File with list of \"chr hap color\".\n", " -p, --prefix Prefix of output files.\n", " -h, -?, --help This help message.\n", "\n"; exit -1; } sub parse_params { my $opts = { #colors => ['red','green','blue','yellow'], colors => ['#ff0000','#008000','#0000ff','#ffff00'], height => 350, pad => 10, dimL => 300, # arm length dimD => 10, # arm width dimE => 7, # arm pad dimB => 5, # arm end curve }; $$opts{chr_width} = 2*$$opts{pad} + 2*$$opts{dimD} + $$opts{dimE}; $$opts{width} = $$opts{chr_width}*23; while (defined(my $arg=shift(@ARGV))) { if ( -e $arg ) { push @{$$opts{files}},$arg; next } if ( $arg eq '-p' || $arg eq '--prefix' ) { $$opts{prefix}=shift(@ARGV); next } if ( $arg eq '-c' || $arg eq '--colors' ) { read_colors($opts,shift(@ARGV)); next; } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } if ( !exists($$opts{files}) ) { error("No files given?\n") } if ( !exists($$opts{prefix}) ) { error("Expected -p option\n") } return $opts; } sub read_colors { my ($opts,$fname) = @_; open(my $fh,'<',$fname) or error("$fname: $!"); while (my $line=<$fh>) { if ( $line=~/^\s*$/ ) { next; } $line =~ s/^\s*//; $line =~ s/\s*$//; my ($chr,$hap,$col) = split(/\s+/,$line); $$opts{hap_cols}{$chr}{$hap} = $col; } close($fh); } sub plot { my ($opts) = @_; my $width = $$opts{width}; my $height = $$opts{height}; my $pad = $$opts{pad}; my $svg = $$opts{svg} = []; push @$svg, q[]; push @$svg, q[]; push @$svg, qq[]; my $xpos = $pad; for my $chr (qw(1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X)) { draw_chr($opts,$chr,$xpos,$pad); $xpos += $$opts{chr_width}; } $xpos = $pad + 10*$$opts{chr_width}; for my $sample (keys %{$$opts{samples}}) { $$opts{chrs}{$sample} = { len=>59e6, acen=>[24e6,26e6,28e6] }; my $chr = $$opts{chrs}{$sample}; my $len1 = $$opts{dimL}*$$chr{acen}[0]/$$opts{max_chr_len}; my $len2 = $$opts{dimL}*$$chr{acen}[2]/$$opts{max_chr_len}; my $len3 = $$opts{dimL}*$$chr{len}/$$opts{max_chr_len}; if ( exists($$opts{samples}{$sample}{1}) ) { my $col = $$opts{samples}{$sample}{1}; $$chr{px1} = [[0,$len1,{$col=>1.0}],[$len2,$len3,{$col=>1.0}]]; } if ( exists($$opts{samples}{$sample}{2}) ) { my $col = $$opts{samples}{$sample}{2}; $$chr{px2} = [[0,$len1,{$col=>1.0}],[$len2,$len3,{$col=>1.0}]]; } my $ypos = $$opts{dimL} - $len3 + $pad; draw_chr($opts,$sample,$xpos,$ypos); $xpos += 2*$$opts{chr_width}; } push @$svg, q[]; open(my $fh,'>',"$$opts{prefix}.svg"); print $fh join("\n",@$svg); close($fh); } sub draw_chr { my ($opts,$chr_name,$xpos,$ypos) = @_; my $svg = $$opts{svg}; my $chr = $$opts{chrs}{$chr_name}; my $dimL = $$opts{dimL}; my $dimC = $dimL*($$chr{acen}[2]-$$chr{acen}[0])/$$opts{max_chr_len}; my $dimL1 = $dimL*$$chr{acen}[0]/$$opts{max_chr_len}; my $dimL2 = $dimL*($$chr{len} - $$chr{acen}[2])/$$opts{max_chr_len}; my $dimD = $$opts{dimD}; # arm width my $dimB = $$opts{dimB}; my $dimE = $$opts{dimE}; # the gap width between arms my $dimE05 = $dimE*0.5; my $dimD05 = $dimD*0.5; my $dimB05 = $dimB*0.5; my $dimC05 = 0.5*$dimC; my $xtext = $xpos + $dimD + $dimE*0.5; my $ytext = $ypos; push @$svg, qq[$chr_name\n]; $ypos += $$opts{pad}; push @$svg, qq[ ]; if ( $$chr{px1} ) { draw_regs($opts,$chr_name,$$chr{px1},$xpos,$ypos); } if ( $$chr{px2} ) { draw_regs($opts,$chr_name,$$chr{px2},$xpos+$dimD+$dimE,$ypos); } } sub parse_hex_color { my ($color) = @_; if ( !($color=~/^#/) ) { error("Could not parse: $color"); } $color =~ s/^#//; my @vals = split(//, $color); my ($r,$g,$b); if ( @vals==6 ) { $r = hex($vals[0].$vals[1]); $g = hex($vals[2].$vals[3]); $b = hex($vals[4].$vals[5]); } elsif ( @vals==3 ) { $r = hex($vals[0].$vals[0]); $g = hex($vals[1].$vals[1]); $b = hex($vals[2].$vals[2]); } else { error("Could not parse: $color\n"); } return ($r,$g,$b); } sub scale_color { my ($color,$scale) = @_; my ($r1,$g1,$b1) = parse_hex_color($color); my ($r0,$g0,$b0) = parse_hex_color('#aaa'); my $r = $scale*($r1-$r0) + $r0; my $g = $scale*($g1-$g0) + $g0; my $b = $scale*($b1-$b0) + $b0; return sprintf("#%0.2x%0.2x%0.2x",$r,$g,$b); } sub draw_regs { my ($opts,$chr_name,$regs,$xpos,$ypos) = @_; my $svg = $$opts{svg}; my $chr = $$opts{chrs}{$chr_name}; my $dimL = $$opts{dimL}; my $dimC = $dimL*($$chr{acen}[2]-$$chr{acen}[0])/$$opts{max_chr_len}; my $dimL1 = $dimL*$$chr{acen}[0]/$$opts{max_chr_len}; my $dimL2 = $$opts{dimL} - $dimL*$$chr{acen}[2]/$$opts{max_chr_len}; my $dimD = $$opts{dimD}; # arm width my $dimB = $$opts{dimB}; my $dimE = $$opts{dimE}; my $dimE05 = $dimE*0.5; my $dimD05 = $dimD*0.5; my $dimB05 = $dimB*0.5; my $dimC05 = 0.5*$dimC; for my $reg (@$regs) { my $sum = 0; my $cmax = undef; for my $c (keys %{$$reg[2]}) { $sum += $$reg[2]{$c}; if ( !defined $cmax or $$reg[2]{$cmax} < $$reg[2]{$c} ) { $cmax = $c; } } my $color = scale_color($cmax,$$reg[2]{$cmax}/$sum); my $y = $ypos + $$reg[0]; my $dy = $$reg[1] - $$reg[0] + 1; push @$svg, qq[ ]; } } sub hap2color { my ($opts,$chr,$hap) = @_; if ( exists($$opts{hap_cols}{$chr}{$hap}) ) { if ( !exists($$opts{hap_cols}{'*'}{$hap}) ) { $$opts{hap_cols}{'*'}{$hap} = $$opts{hap_cols}{$chr}{$hap}; } return $$opts{hap_cols}{$chr}{$hap}; } elsif ( exists($$opts{hap_cols}{'*'}{$hap}) ) { return $$opts{hap_cols}{'*'}{$hap}; } if ( !exists($$opts{haps}) ) { $$opts{haps} = {}; } if ( !exists($$opts{haps}{$hap}) ) { my $nhaps = scalar keys %{$$opts{haps}}; my $color = $$opts{colors}[$nhaps]; $$opts{haps}{$hap} = $color; } return $$opts{haps}{$hap}; } sub read_dat { my ($opts,$file) = @_; open(my $fh,'<',$file) or error("$file: $!"); while (my $line=<$fh>) { if ( !($line=~/^SG/) ) { next; } my @items = split(/\s+/,$line); my $chr = $items[1]; my $start = $items[2]; my $end = $items[3]; my $hap1 = $items[4]; my $hap2 = $items[5]; my $col1 = hap2color($opts,$chr,$hap1); my $col2 = hap2color($opts,$chr,$hap2); push @{$$opts{chrs}{$chr}{regs1}},[$start,$end,$col1]; push @{$$opts{chrs}{$chr}{regs2}},[$start,$end,$col2]; my ($smpl,$hap); ($smpl,$hap) = split(/:/,$hap1); $$opts{samples}{$smpl}{$hap} = $col1; ($smpl,$hap) = split(/:/,$hap2); $$opts{samples}{$smpl}{$hap} = $col2; } close($fh); } sub merge_regs { my ($opts) = @_; for my $chr (keys %{$$opts{chrs}}) { my $dat = $$opts{chrs}{$chr}; if ( exists($$dat{regs1}) ) { $$dat{px1} = merge($opts,$dat,$$dat{regs1}); } if ( exists($$dat{regs2}) ) { $$dat{px2} = merge($opts,$dat,$$dat{regs2}); } } } sub merge { my ($opts,$chr_dat,$regs) = @_; # merge adjacent regions of the same color for (my $i=1; $i<@$regs; $i++) { if ( $$regs[$i-1][2] eq $$regs[$i][2] ) { $$regs[$i-1][1] = $$regs[$i][1]; splice(@$regs,$i,1); $i--; next; } } for (my $i=0; $i<@$regs; $i++) { if ( $$regs[$i][1] < $$chr_dat{acen}[0] ) { next; } if ( $$regs[$i][0] > $$chr_dat{acen}[2] ) { next; } if ( $$regs[$i][0] >= $$chr_dat{acen}[0] && $$regs[$i][1] <= $$chr_dat{acen}[2] ) { splice(@$regs,$i,1); $i--; next; } if ( $$regs[$i][1] < $$chr_dat{acen}[2] ) { $$regs[$i][1] = $$chr_dat{acen}[0]; next; } if ( $$regs[$i][0] > $$chr_dat{acen}[0] ) { $$regs[$i][0] = $$chr_dat{acen}[2]; next; } my $start = $$chr_dat{acen}[2]; my $end = $$regs[$i][1]; my $color = $$regs[$i][2]; $$regs[$i][1] = $$chr_dat{acen}[0]; splice(@$regs,$i+1,0,[$start,$end,$color]); } # pixelize my @px = ([0,0,{}]); # start,end,hash of contributions from colors my $dy = $$opts{max_chr_len}/$$opts{dimL}; # 1px covers $dy base pairs for my $reg (@$regs) { my $px_start = int($$reg[0] / $dy); my $px_end = int($$reg[1] / $dy); my $color = $$reg[2]; my $contrib = ($$reg[1] - $$reg[0])/$dy; if ( $px_start==$px_end ) { if ( $px_end<=$px[-1][1] ) { $px[-1][2]{$color} += $contrib; } else { push @px, [$px_start,$px_end,{$color=>$contrib}]; } next; } my $rem_start = 1 - ($$reg[0]/$dy - $px_start); # fractional remainders my $rem_end = $$reg[1]/$dy - $px_end; if ( $px_start==$px[-1][1] ) { $px[-1][2]{$color} += $rem_start; } if ( $px_end==$px[-1][1] ) { $px[-1][2]{$color} += $rem_end; if ( $px_start+1<$px_end ) { error("really?!\n"); } } elsif ( $px_end>$px[-1][1] ) { if ( $rem_start ) { $px_start++; $contrib -= $rem_start; } push @px, [ $px_start, $px_end, { $color=>$contrib } ]; } else { error("really?!\n"); } } return \@px; } sub chr_dims { my ($opts) = @_; # http://hgdownload.cse.ucsc.edu/goldenPath/hg19/database/cytoBand.txt.gz my $ktype = q[ chr1 121500000 125000000 p11.1 acen chr1 125000000 128900000 q11 acen chr1 243700000 249250621 q44 gneg chr10 38000000 40200000 p11.1 acen chr10 40200000 42300000 q11.1 acen chr10 130600000 135534747 q26.3 gneg chr11 51600000 53700000 p11.11 acen chr11 53700000 55700000 q11 acen chr11 130800000 135006516 q25 gneg chr12 33300000 35800000 p11.1 acen chr12 35800000 38200000 q11 acen chr12 129300000 133851895 q24.33 gneg chr13 16300000 17900000 p11.1 acen chr13 17900000 19500000 q11 acen chr13 110300000 115169878 q34 gneg chr14 16100000 17600000 p11.1 acen chr14 17600000 19100000 q11.1 acen chr14 104000000 107349540 q32.33 gneg chr15 15800000 19000000 p11.1 acen chr15 19000000 20700000 q11.1 acen chr15 98500000 102531392 q26.3 gneg chr16 34600000 36600000 p11.1 acen chr16 36600000 38600000 q11.1 acen chr16 88700000 90354753 q24.3 gneg chr17 22200000 24000000 p11.1 acen chr17 24000000 25800000 q11.1 acen chr17 75300000 81195210 q25.3 gneg chr18 15400000 17200000 p11.1 acen chr18 17200000 19000000 q11.1 acen chr18 73100000 78077248 q23 gneg chr19 24400000 26500000 p11 acen chr19 26500000 28600000 q11 acen chr19 56300000 59128983 q13.43 gpos25 chr2 90500000 93300000 p11.1 acen chr2 93300000 96800000 q11.1 acen chr2 237300000 243199373 q37.3 gneg chr20 25600000 27500000 p11.1 acen chr20 27500000 29400000 q11.1 acen chr20 58400000 63025520 q13.33 gneg chr21 10900000 13200000 p11.1 acen chr21 13200000 14300000 q11.1 acen chr21 42600000 48129895 q22.3 gneg chr22 12200000 14700000 p11.1 acen chr22 14700000 17900000 q11.1 acen chr22 49400000 51304566 q13.33 gneg chr3 87900000 91000000 p11.1 acen chr3 91000000 93900000 q11.1 acen chr3 192300000 198022430 q29 gneg chr4 48200000 50400000 p11 acen chr4 50400000 52700000 q11 acen chr4 187100000 191154276 q35.2 gpos25 chr5 46100000 48400000 p11 acen chr5 48400000 50700000 q11.1 acen chr5 176600000 180915260 q35.3 gneg chr6 58700000 61000000 p11.1 acen chr6 61000000 63300000 q11.1 acen chr6 164500000 171115067 q27 gneg chr7 58000000 59900000 p11.1 acen chr7 59900000 61700000 q11.1 acen chr7 155100000 159138663 q36.3 gneg chr8 43100000 45600000 p11.1 acen chr8 45600000 48100000 q11.1 acen chr8 139900000 146364022 q24.3 gneg chr9 47300000 49000000 p11.1 acen chr9 49000000 50700000 q11 acen chr9 137400000 141213431 q34.3 gneg chrX 58100000 60600000 p11.1 acen chrX 60600000 63000000 q11.1 acen chrX 147100000 155270560 q28 gneg ]; my @lines = split(/\n/,$ktype); my %chrs = (); my $max_len = 0; for my $line (@lines) { if ( $line =~ /^\s*$/ ) { next; } $line =~ s/^\s*//; $line =~ s/\s*$//; my @items = split(/\s+/,$line); my $chr = $items[0]; my $start = $items[1]; my $end = $items[2]; $chr =~ s/^chr//; if ( $items[-1] eq 'acen' ) { push @{$chrs{$chr}{acen}},$start; push @{$chrs{$chr}{acen}},$end; } if ( !defined $chrs{$chr}{len} or $chrs{$chr}{len} < $end ) { $chrs{$chr}{len} = $end; } if ( $max_len < $end ) { $max_len = $end; } } for my $chr (keys %chrs) { splice(@{$chrs{$chr}{acen}},1,1); } $$opts{chrs} = \%chrs; $$opts{max_chr_len} = $max_len; } bcftools-1.21/misc/demo-flt.pl000066400000000000000000000051031467060157400162600ustar00rootroot00000000000000# This demo code shows how to write a custom perl code and use it in # the -i/-e filtering expressions. # # In this example we want to take variant consequences generated by `bcftools csq`, # rank them by severity, filter by the most severe, and print the list using the # following command: # # bcftools query -f '%CHROM:%POS \t %CSQ\n' -i 'perl:misc/demo-flt.pl; perl.severity(INFO/CSQ) > 10' test/perl-flt.vcf # # There can be multiple subroutines in the same script and they # can be referenced from the command line by prefixing "perl.subroutine_name()" # sub severity { # Arbitrary number of arguments can be provided. my (@args) = @_; # Note that string arrays are passed to perl in the form of a single # comma-separated string, but numeric arrays must be dereferenced, for # example as shown in this example: # # for my $arg (@args) # { # if ( ref($arg) eq 'ARRAY' ) { print "array: ".join(',',@$arg)."\n"; } # else { print "scalar: $arg\n"; } # } # # In our case there should be only one parameter passed to the subroutine; # check if this is the case if ( scalar @args != 1 ) { error("Incorrect use, expected one argument, got ".scalar @args."!\n"); } # Create a lookup table from consequences to an arbitrary severity score my %severity = ( "intergenic" => 1, "intron" => 2, "non_coding" => 3, "5_prime_utr" => 4, "3_prime_utr" => 5, "stop_retained" => 6, "synonymous" => 7, "coding_sequence" => 8, "missense" => 9, "splice_region" => 10, "inframe_altering" => 11, "inframe_deletion" => 12, "inframe_insertion" => 13, "splice_acceptor" => 14, "splice_donor" => 15, "stop_lost" => 16, "stop_gained" => 17, "start_lost" => 18, "frameshift" => 19, ); # Split multiple consequences into an array my @csq = split(/,/, $args[0]); # Find the most severe consequence. The consequence string may look like this: # inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T my $max = 0; for my $csq (@csq) { my @fields = split(/\|/, $csq); my $string = $fields[0]; my $score = exists($severity{$string}) ? $severity{$string} : 0; if ( $max < $score ) { $max = $score; } } return $max; } sub error { my (@msg) = @_; print STDERR @msg; exit 1; } bcftools-1.21/misc/fix-broken-GATK-Double-vs-Integer000077500000000000000000000125111467060157400221640ustar00rootroot00000000000000#!/usr/bin/env perl # # The MIT License # # Copyright (c) 2017-2018 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE # AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, # OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN # THE SOFTWARE. use strict; use warnings; use Carp; my $opts = parse_params(); fix($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "About:\n", " Some parts of GATK throw errors like\n", " \"java.lang.Double cannot be cast to java.lang.Integer\"\n", " This is caused by a bug in GATK which incorrectly parses valid float number expressions, for example\n", " it would not accept \"0\", only \"0.0\". Such unnecessary strictness violates the VCF specification\n", " (and common sense). This script reformats floating point fields to work around this.\n", "\n", "Usage: fix-broken-GATK-Double-vs-Integer [OPTIONS]\n", "Options:\n", " -c, --check-only check for problems, do not output VCF\n", " -h, --help this help message\n", "\n", "Example:\n", " gunzip -c ori.vcf.gz | fix-broken-GATK-Double-vs-Integer | bgzip -c > new.vcf.gz\n", "\n"; exit -1; } sub parse_params { my $opts = { nflt => 0, nint => 0, }; while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '-c' || $arg eq '--check-only' ) { $$opts{check_only} = 1; next; } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } return $opts; } sub fix { my ($opts) = @_; while (my $line=) { if ( $line=~/^#/ ) { $line = parse_header($opts,$line); } else { $line = fix_line($opts,$line); } if ( !$$opts{check_only} ) { print $line; } } print STDERR "Modified $$opts{nflt} float values, $$opts{nint} integer values\n"; } sub parse_header { my ($opts,$line) = @_; my $coltype = undef; if ( $line=~/^##INFO/ ) { $coltype = 'info'; } elsif ( $line=~/^##FORMAT/ ) { $coltype = 'fmt'; } else { return $line; } if ( !($line=~/ID=([^,>]+)/) ) { return $line; } my $id = $1; my $type = undef; if ( $line=~/Type=Float/ ) { $type = 'float'; } elsif ( $line=~/Type=Integer/ ) { $type = 'int'; } else { return $line; } $$opts{$coltype}{$id} = $type; return $line; } sub fix_line { my ($opts,$line) = @_; my $info = $$opts{info}; my $fmt = $$opts{fmt}; my @cols = split(/\t/,$line); my @info = split(/;/,$cols[7]); my @fmt = split(/:/,$cols[8]); my $pos = "$cols[0]:$cols[1]"; chomp($cols[-1]); for (my $i=0; $i<@info; $i++) { my ($key,$val) = split(/=/,$info[$i]); if ( !defined $val or !exists($$info{$key}) ) { next; } $val = $$info{$key} eq 'float' ? fix_float($opts,$pos,$key,$val) : fix_int($opts,$pos,$key,$val); $info[$i] = "$key=$val"; } $cols[7] = join(';',@info); for (my $j=9; $j<@cols; $j++) { my @vals = split(/:/,$cols[$j]); for (my $i=0; $i<@fmt; $i++) { my $key = $fmt[$i]; if ( !exists($$fmt{$key}) ) { next; } if ( !exists($vals[$i]) ) { last; } $vals[$i] = $$fmt{$key} eq 'float' ? fix_float($opts,$pos,$key,$vals[$i]) : fix_int($opts,$pos,$key,$vals[$i]); } $cols[$j] = join(':',@vals); } return join("\t",@cols)."\n"; } sub fix_int { my ($opts,$pos,$key,$vals) = @_; my @vals = split(/,/,$vals); for (my $i=0; $i<@vals; $i++) { if ( $vals[$i] eq '.' ) { next; } if ( $vals[$i] =~ /^-?[0-9]+$/ ) { next; } if ( $$opts{check_only} ) { print "$pos\t$key\tInteger\t$vals[$i]\n"; } error("todo: $pos\t$key\tInteger\t$vals[$i]\n"); $$opts{nint}++; } return $vals; } sub fix_float { my ($opts,$pos,$key,$vals) = @_; my @vals = split(/,/,$vals); for (my $i=0; $i<@vals; $i++) { if ( $vals[$i] eq '.' ) { next; } if ( $vals[$i] =~ /\./ ) { next; } if ( $vals[$i] =~ /[eE]/ ) { next; } if ( $$opts{check_only} ) { print "$pos\t$key\tFloat\t$vals[$i]\n"; } $vals[$i] .= '.'; $$opts{nflt}++; } return join(',',@vals); } bcftools-1.21/misc/gff2gff000077500000000000000000000144741467060157400154640ustar00rootroot00000000000000#!/usr/bin/env perl # # Copyright (C) 2023 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. use strict; use warnings; use Carp; my $opts = parse_params(); gff2gff($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "About: Attempt to fix a GFF file to be correctly parsed by bcftools/csq, see\n", " the man page for the description of the expected format\n", " http://samtools.github.io/bcftools/bcftools-man.html#csq\n", "Usage: gff2gff [OPTIONS]\n", "Options:\n", " -v, --verbose Increase verbosity\n", " -h, -?, --help This help message\n", "Example:\n", " zcat in.gff.gz | gff2gff | gzip -c > out.gff.gz\n", "\n"; exit -1; } sub parse_params { my $opts = { verbose=>0, warned=>{}, fixed=>{} }; if ( -t STDIN && !@ARGV ) { error(); } while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '-v' or $arg eq '--verbose' ) { $$opts{verbose}++; next; } if ( $arg eq '-?' or $arg eq '-h' or $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } return $opts; } sub gff2gff { my ($opts) = @_; while (my $line=) { if ( $line=~/^#/ ) { print $line; next; } my @row = split(/\t/,$line); chomp($row[-1]); if ( $row[2] eq 'gene' ) { fix_gene($opts,$line,\@row); } elsif ( $row[2] eq 'transcript' ) { fix_transcript($opts,$line,\@row); } elsif ( $row[8]=~/biotype=/ && !($row[8]=~/Parent=/) ) { fix_gene($opts,$line,\@row); } elsif ( $row[8]=~/Parent=/ ) { fix_transcript($opts,$line,\@row); } print join("\t",@row)."\n"; } if ( !$$opts{verbose} ) { my $nwarn = 0; for my $key (keys %{$$opts{warned}}) { if ( $$opts{warned}{$key} > 1 ) { $nwarn += $$opts{warned}{$key} - 1; } } if ( $nwarn ) { print STDERR "Suppressed $nwarn warnings, run with -v to see them all\n"; } } my $nfixed = 0; for my $key (keys %{$$opts{fixed}}) { $nfixed += $$opts{fixed}{$key}; } print STDERR "Fixed $nfixed records\n"; for my $key (sort {$$opts{fixed}{$b}<=>$$opts{fixed}{$a}} keys %{$$opts{fixed}}) { print STDERR "\t$$opts{fixed}{$key}x .. $key\n"; } } sub fix_gene { my ($opts,$line,$row) = @_; my ($id,$biotype,$name); my $id_ok = 0; my $biotype_ok = 0; my $name_ok = 0; if ( $$row[8] =~ /ID=([^;]+)/ ) { $id = $1; $id_ok = 1; } if ( !$id_ok && $$row[8] =~ /gene_id=([^;]+)/i ) { $id = $1; } if ( $$row[8] =~ /biotype=([^;]+)/ ) { $biotype = $1; $biotype_ok = 1; } if ( !$biotype_ok && $$row[8] =~ /gene_type=([^;]+)/i ) { $biotype = $1; } if ( $$row[8] =~ /Name=([^;]+)/ ) { $name = $1; $name_ok = 1; } if ( !$name_ok && $$row[8] =~ /gene_name=([^;]+)/i ) { $name = $1; } if ( !$id_ok ) { if ( defined $id ) { $$row[8] .= ";ID=$id"; $$opts{fixed}{gene_id}++; } else { if ( $$opts{verbose}>0 or !$$opts{warned}{gene_id} ) { print STDERR "Unable to determine gene ID: $line"; } $$opts{warned}{gene_id}++; } } if ( !$biotype_ok && defined $biotype ) { $$row[8] .= ";biotype=$biotype"; $$opts{fixed}{gene_biotype}++; } if ( !$name_ok && defined $name ) { $$row[8] .= ";Name=$name"; $$opts{fixed}{gene_name}++; } if ( defined $biotype ) { $$opts{gene_id2biotype}{$id} = $biotype; } } sub fix_transcript { my ($opts,$line,$row) = @_; my ($id,$biotype,$parent); my $id_ok = 0; my $biotype_ok = 0; my $parent_ok = 0; if ( $$row[8] =~ /ID=([^;]+)/ ) { $id = $1; $id_ok = 1; } if ( !$id_ok && $$row[8] =~ /transcript_id=([^;]+)/i ) { $id = $1; } if ( $$row[8] =~ /biotype=([^;]+)/ ) { $biotype = $1; $biotype_ok = 1; } if ( !$biotype_ok && $$row[8] =~ /transcript_type=([^;]+)/i ) { $biotype = $1; } if ( $$row[8] =~ /Parent=([^;]+)/ ) { $parent = $1; $parent_ok = 1; } if ( !$id_ok ) { if ( defined $id ) { $$row[8] .= ";ID=$id"; $$opts{fixed}{transcript_id}++; } else { if ( $$opts{verbose}>0 or !$$opts{warned}{tscript_id} ) { print STDERR "Unable to determine transcript ID: $line"; } $$opts{warned}{tscript_id}++; } } if ( !$biotype_ok ) { if ( defined $biotype ) { $$row[8] .= ";biotype=$biotype"; $$opts{fixed}{transcript_biotype}++; } elsif ( defined $parent && exists($$opts{gene_id2biotype}{$parent}) ) { $$row[8] .= ";biotype=$$opts{gene_id2biotype}{$parent}"; $$opts{fixed}{transcript_biotype}++; } else { if ( $$opts{verbose}>0 or !$$opts{warned}{tscript_biotype} ) { print STDERR "Unable to determine transcript biotype/type: $line"; } $$opts{warned}{tscript_biotype}++; } } if ( !$parent_ok ) { if ( defined $parent ) { $$row[8] .= ";Parent=$parent"; $$opts{fixed}{transcript_parent}++; } # currently cannot happen else { if ( $$opts{verbose}>0 or !$$opts{warned}{tscript_parent} ) { print STDERR "Unable to determine transcript Parent: $line"; } $$opts{warned}{tscript_parent}++; } } } bcftools-1.21/misc/gff2gff.py000077500000000000000000000163551467060157400161130ustar00rootroot00000000000000#!/usr/bin/env python3 # # This is script was contributed by Philip Ashton (https://github.com/flashton2003) # with the intention to convert from the many GFF flavours to the Ensembl GFF3 format # supported by bcftools csq. Please expand as necessary and send a pull request. # # See also # https://github.com/samtools/bcftools/issues/530#issuecomment-268278248 # https://github.com/samtools/bcftools/issues/1078#issuecomment-527484831 # https://github.com/samtools/bcftools/issues/1208#issuecomment-620642373 # import sys import gffutils class PseudoFeature(): def __init__(self, chrom, start, stop, strand): self.chrom = chrom self.start = start self.stop = stop self.strand = strand class FeatureGroup(): def __init__(self, gene_id): ## see here https://github.com/samtools/bcftools/issues/530#issuecomment-614410603 self.id = gene_id ## the below should be lists of instances of Feature class. self.gene = None # one feature group should have a single gene self.transcript = None ## assuming here that ncRNA is more like transcript than exon ## i.e. there is only one ncRNA feature per feature group. self.ncRNA = None self.exons = [] self.CDSs = [] def add_gene(self, feature): self.gene = feature def add_transcript(self, feature): self.transcript = feature # one feature group should have a single gene def add_exon(self, feature): self.exons.append(feature) def add_cds(self, feature): self.CDSs.append(feature) def add_ncRNA(self, feature): self.ncRNA = feature def get_args(): if len(sys.argv) != 3: print('Usage: gff2gff.py ') sys.exit() else: return sys.argv[1], sys.argv[2] def group_features(db): feature_groups = {} for feature in db.all_features(): if feature.featuretype not in ('repeat_region', 'regulatory', 'stem_loop', 'gene_component_region', 'repeat_region'): if feature.featuretype == 'gene': ## for any particular feature group, the gene doesn't necassarily come ## before the CDS in the gff, so need to have the if/else logic gene_id = feature.id.split('.')[0] if gene_id not in feature_groups: feature_groups[gene_id] = FeatureGroup(gene_id) feature_groups[gene_id].add_gene(feature) else: feature_groups[gene_id].add_gene(feature) ## in this gff, the transcripts are referred to as mRNA ## not all genes have mRNA records elif feature.featuretype == 'mRNA': gene_id = feature.id.split('.')[0] # print(feature.id) # print(gene_id) feature_groups[gene_id].add_transcript(feature) elif feature.featuretype == 'exon': gene_id = feature.attributes['locus_tag'][0] if gene_id not in feature_groups: feature_groups[gene_id] = FeatureGroup(gene_id) feature_groups[gene_id].add_exon(feature) else: feature_groups[gene_id].add_exon(feature) elif feature.featuretype == 'CDS': gene_id = feature.attributes['locus_tag'][0] if gene_id not in feature_groups: feature_groups[gene_id] = FeatureGroup(gene_id) feature_groups[gene_id].add_cds(feature) else: feature_groups[gene_id].add_cds(feature) elif feature.featuretype == 'ncRNA': gene_id = feature.attributes['locus_tag'][0] # print(gene_id) if gene_id not in feature_groups: feature_groups[gene_id] = FeatureGroup(gene_id) feature_groups[gene_id].add_ncRNA(feature) else: feature_groups[gene_id].add_ncRNA(feature) return feature_groups def make_transcript_pseudofeature(CDSs): ## takes list of CDSs, list len will often be 1, but will sometimes be 2 start = min([x.start for x in CDSs]) stop = max([x.stop for x in CDSs]) chrom = CDSs[0].chrom ## check that both on the same strand assert len(set([x.strand for x in CDSs])) == 1 strand = CDSs[0].strand pf = PseudoFeature(chrom, start, stop, strand) return pf def check_feature_groups(feature_groups): ## checking that feature group has a gene, at least one CDS, and a transcript ## if doesn't have a transcript (as many don't), then make a pseudo feature corresponding to a transcript ## only checking that have transcript for everything for gene_id in feature_groups: ## don't want to analyse ncRNAs here, but need to include them up ## to this point so that we know that that gene is an ncRNA gene if feature_groups[gene_id].ncRNA != None: continue assert feature_groups[gene_id].gene != None assert len(feature_groups[gene_id].CDSs) > 0 if feature_groups[gene_id].transcript == None: ## using pseudofeature because the gffutils feature says it's not really intended ## for direct instantiation by users feature_groups[gene_id].transcript = make_transcript_pseudofeature(feature_groups[gene_id].CDSs) def print_features(feature_groups): for gene_id in feature_groups: feature_group = feature_groups[gene_id] if feature_group.ncRNA != None: continue print('###') name = feature_group.gene.attributes['Name'][0] gene_attributes = f'ID=gene:{gene_id};Name={name};biotype=protein_coding;gene_id:{gene_id}' print(feature_group.gene.chrom, 'EMBL', 'gene', feature_group.gene.start, feature_group.gene.stop, '.', feature_group.gene.strand, '.', gene_attributes, sep = '\t') transcript_attributes = f'ID=transcript:{gene_id};Parent=gene:{gene_id};Name={name};biotype=protein_coding;transcript_id={gene_id}' print(feature_group.transcript.chrom, 'EMBL', 'transcript', feature_group.transcript.start, feature_group.transcript.stop, '.', feature_group.transcript.strand, '.', transcript_attributes, sep = '\t') cds_attributes = f'Parent=transcript:{gene_id};Name={name}' for c in feature_group.CDSs: print(c.chrom, 'EMBL', 'CDS', c.start, c.stop, '.', c.strand, '0', cds_attributes, sep = '\t') def main(): ''' Ensembl gff should have one gene and one transcript per "feature group" Then, can have multiple CDS/exons read in from the input gff, one FeatureGroup instance has one gene, one transcript and (potentially) multiple CDS/exon Exons aren't printed, as not needed bt bcftools csq ''' gff_handle, db_handle = get_args() fn = gffutils.example_filename(gff_handle) db = gffutils.create_db(fn, dbfn=db_handle, force=True, keep_order=True,merge_strategy='merge', sort_attribute_values=True) feature_groups = group_features(db) check_feature_groups(feature_groups) print_features(feature_groups) ## gff input is generated from a genbank file by bp_genbank2gff3.pl if __name__ == '__main__': main() bcftools-1.21/misc/guess-ploidy.py000077500000000000000000000104111467060157400172130ustar00rootroot00000000000000#!/usr/bin/env python # # Plot the output of "bcftools +guess-ploidy -v" # # Copyright (C) 2016-2017 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. from __future__ import print_function import matplotlib as mpl mpl.use('Agg') import matplotlib.pyplot as plt import matplotlib.gridspec as gridspec import random, math, sys import csv csv.register_dialect('tab', delimiter='\t', quoting=csv.QUOTE_NONE) if len(sys.argv) != 3: print("""\ About: Plot output of "bcftools +guess-ploidy -v" Usage: guess-ploidy.py """, file = sys.stderr) sys.exit() prefix = sys.argv[2] dpi = 150 def add_value(dat,key,x,y): if key not in dat: dat[key] = [] dat[key].append([x,y]) smpl2sex = {} dat = {} with open(sys.argv[1]) as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0]=="#": continue if row[0]=="SEX": smpl = row[1] sex = row[2] phap = float(row[3]) pdip = float(row[4]) ndat = float(row[5]) score = float(row[6]) smpl2sex[smpl] = sex add_value(dat,'score',smpl,score) add_value(dat,'phap',smpl,phap) add_value(dat,'pdip',smpl,pdip) add_value(dat,'ndat',smpl,ndat) def sort_by_val(arr): for x in (sorted(arr, key=lambda x:x[1])): id = len(smpl2id) smpl2id[x[0]] = id arr = sorted(arr, key=lambda x:smpl2id[x[0]]) return arr def select_sex(arr,sex): out = [] for x in arr: if smpl2sex[x[0]]==sex: out.append(x) return out col = {} col['blue'] = '#396ab1' col['orange'] = '#da7c30' col['green'] = '#3e9651' col['red'] = '#cc2529' col['grey'] = '#000000' col['purple'] = '#6b4c9a' col['yellow'] = '#ccc210' if True: fig,ax1 = plt.subplots(1,1,figsize=(6,4)) smpl2id = {} dat['score'] = sort_by_val(dat['score']) dat['scoreM'] = select_sex(dat['score'],'M') dat['scoreF'] = select_sex(dat['score'],'F') ax2 = ax1.twinx() plots = ax2.plot([smpl2id[x[0]] for x in dat['ndat']],[x[1] for x in dat['ndat']],'v',color=col['grey'],ms=2,label='Number of sites') plots += ax1.plot([smpl2id[x[0]] for x in dat['phap']],[x[1] for x in dat['phap']],'.',color=col['blue'],ms=3,label='log P(haploid)') plots += ax1.plot([smpl2id[x[0]] for x in dat['pdip']],[x[1] for x in dat['pdip']],'.',color=col['yellow'],ms=3,label='log P(diploid)') plots += ax1.plot([smpl2id[x[0]] for x in dat['scoreM']],[x[1] for x in dat['scoreM']],'.',color=col['green'],label='Total score: Males') plots += ax1.plot([smpl2id[x[0]] for x in dat['scoreF']],[x[1] for x in dat['scoreF']],'.',color=col['red'],label='Total score: Females') labels = [l.get_label() for l in plots] ax1.legend(plots,labels,loc='best', frameon=False, numpoints=1, prop={'size':9}) ax1.set_zorder(ax2.get_zorder()+1) ax1.patch.set_visible(False) ax1.set_xlabel('Sample') ax1.set_ylabel('Score') ax2.set_ylabel('Number of sites') ax2.set_yscale('log') # ax1.set_yscale('log') ax1.ticklabel_format(style='sci', scilimits=(-3,4), axis='x') plt.subplots_adjust(left=0.13,right=0.89,bottom=0.13,top=0.9,hspace=0.1) plt.savefig(prefix+'.png',dpi=dpi) plt.close() bcftools-1.21/misc/plot-roh.py000077500000000000000000000364201467060157400163430ustar00rootroot00000000000000#!/usr/bin/env python3 # # The MIT License # # Copyright (c) 2017-2022 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE # AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, # OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN # THE SOFTWARE. import glob, gzip, csv, sys, os, copy, re csv.register_dialect('tab', delimiter='\t', quoting=csv.QUOTE_NONE) def usage(msg=None): if msg==None: print("""\ Usage: plot-roh.py [OPTIONS] Options: -H, --highlight +group1,-group2 Highlight calls shared within group1 but not present in group2 -i, --interactive Run interactively -l, --min-length Filter input regions shorter than this [0] -n, --min-markers Filter input regions with fewer marker than this [0] -o, --outfile Output file name [plot.png] -q, --min-qual Filter input regions with quality smaller than this [0] -r, --region [^] Plot this chromosome/region only -s, --samples List of samples to show, rename or group: "name[\\tnew_name[\\tgroup]]" -h, --help This usage text Matplotlib options: +adj, --adjust Set plot adjust [bottom=0.18,left=0.07,right=0.98] +dpi, --dpi Set bitmap DPI [150] +sxt, --show-xticks Show x-ticks (genomic coordinate) +twh, --track-wh Set track width and height [20,1] +xlb, --xlabel Set x-label +xli, --xlimit Extend x-range by this fraction [0.05]""") else: print(msg) sys.exit(1) dir = None plot_regions = None min_length = 0 min_markers = 0 min_qual = 0 interactive = False sample_file = None highlight = None outfile = None adjust = 'bottom=0.18,left=0.07,right=0.98' dpi = 150 xlim = 0.05 show_xticks = False xlabel = None track_width = 20 track_height = 1 if len(sys.argv) < 2: usage() args = sys.argv[1:] while len(args): if args[0]=='-r' or args[0]=='--region': args = args[1:] plot_regions = args[0] elif args[0]=='-i' or args[0]=='--interactive': interactive = True elif args[0]=='-l' or args[0]=='--min-length': args = args[1:] min_length = float(args[0]) elif args[0]=='-n' or args[0]=='--min-markers': args = args[1:] min_markers = float(args[0]) elif args[0]=='-o' or args[0]=='--outfile': args = args[1:] outfile = args[0] elif args[0]=='-q' or args[0]=='--min-qual': args = args[1:] min_qual = float(args[0]) elif args[0]=='-H' or args[0]=='--highlight': args = args[1:] highlight = args[0] elif args[0]=='-s' or args[0]=='--samples': args = args[1:] sample_file = args[0] elif args[0]=='-?' or args[0]=='-h' or args[0]=='--help': usage() elif args[0]=='+adj' or args[0]=='--adjust': args = args[1:] adjust = args[0] elif args[0]=='+dpi' or args[0]=='--dpi': args = args[1:] dpi = float(args[0]) elif args[0]=='+sxt' or args[0]=='--show-xticks': show_xticks = True elif args[0]=='+twh' or args[0]=='--track-wh': args = args[1:] (track_width,track_height) = args[0].split(',') track_height = -float(track_height) # will be used as if negative, no auto-magic track_width = float(track_width) elif args[0]=='+xlb' or args[0]=='--xlabel': args = args[1:] xlabel = args[0] elif args[0]=='+xli' or args[0]=='--xlimit': args = args[1:] xlim = float(args[0]) else: dir = args[0] args = args[1:] if interactive and outfile!=None: usage("Use -i, --interactive or -o, --outfile, but not both") if not interactive and outfile==None: outfile = 'plot.png' def wrap_hash(**args): return args adjust = eval("wrap_hash("+adjust+")") import matplotlib as mpl if interactive==False: mpl.use('Agg') import matplotlib.pyplot as plt import matplotlib.patches as patches else: gui_set = False; for gui in ['TKAgg','GTKAgg','Qt4Agg','WXAgg','MacOSX']: try: mpl.use(gui,warn=False, force=True) import matplotlib.pyplot as plt import matplotlib.patches as patches gui_set = True; break except: continue if gui_set==False: usage("Unable to set GUI for interactive plot") cols = [ '#337ab7', '#5cb85c', '#5bc0de', '#f0ad4e', '#d9534f', 'grey', 'black' ] globstr = os.path.join(dir, '*.txt.gz') fnames = glob.glob(globstr) if len(fnames)==0: usage("No data files found in \""+dir+"\"") def parse_regions(str): if str==None: return None regs = { 'inc':[], 'exc':[] } list = str.split(',') key = 'inc' if list[0][0]=='^': key = 'exc' list[0] = list[0][1:] for reg in list: x = reg.split(':') chr = x[0] beg = 0 end = (1<<32)-1 if len(x)>1: (beg,end) = x[1].split('-') beg = float(beg) end = float(end) regs[key].append({'chr':chr,'beg':beg,'end':end}) return regs def region_overlap(regs,chr,beg,end): if regs==None: return (beg,end) if len(regs['exc'])>0: for reg in regs['exc']: if chr==reg['chr']: return None return (beg,end) if len(regs['inc'])==0: return (beg,end) for reg in regs['inc']: if chr!=reg['chr']: continue if beg>reg['end']: continue if endreg['end']: end = reg['end'] return (beg,end) return None def parse_outfile(fname): files = re.split(r',',fname) bname = re.search(r'^(.+)\.[^.]+$', files[0]).group(1) for i in range(len(files)-1): files[i+1] = bname+"."+files[i+1] return files def next_region(rgs): min = None for smpl in rgs: if len(rgs[smpl])==0: continue reg = rgs[smpl][0] if min==None: min = [0,0] min[0] = reg[0] min[1] = reg[1] if min[0] > reg[0]: min[0] = reg[0] if min==None: return None for smpl in rgs: if len(rgs[smpl])==0: continue reg = rgs[smpl][0] if min[1] > reg[1]: min[1] = reg[1] if min[1] > reg[0] - 1 and min[0] != reg[0]: min[1] = reg[0] - 1 return min; def merge_regions(rg): rgs = copy.deepcopy(rg) out = {} while True: min = next_region(rgs) if min==None: break beg = min[0] end = min[1] smpls = [] for smpl in rgs: if len(rgs[smpl])==0: continue reg = rgs[smpl][0] if reg[0] > end: continue if reg[1] > end: rgs[smpl][0][0] = end + 1 else: rgs[smpl] = rgs[smpl][1:] if smpl not in out: out[smpl] = [] smpls.append(smpl) if len(smpls)>1: for smpl in smpls: out[smpl].append([beg,end]) return out def prune_regions(groups,regions): regs = {'+':{},'-':{}} for smpl in regions: grp = groups[smpl] for reg in regions[smpl]: key = str(reg[0])+"-"+str(reg[1]) # reg=[beg,end] -> "beg-end" if key not in regs[grp]: regs[grp][key] = 0 regs[grp][key] += 1 nexp = 0 for smpl in groups: if groups[smpl]=='+': nexp += 1 for smpl in regions: rm = [] for reg in regions[smpl]: key = str(reg[0])+"-"+str(reg[1]) if key in regs['-']: rm.append(reg) elif key not in regs['+'] or regs['+'][key]!=nexp: rm.append(reg) for reg in rm: if reg in regions[smpl]: regions[smpl].remove(reg) return regions def parse_samples(fname,highlight): if fname==None: return (None,None,{}) samples = {} groups = {} grp2sgn = {} smpl2y = {} # parse "+name" to create a map "name":"+" if highlight!=None: for grp in re.split(r',', highlight): if grp[0]!='+' and grp[0]!='-': usage("Expected + or - before the group name: "+grp) grp2sgn[grp[1:]] = grp[0] # read samples, renaming them with open(fname) as f: for line in f: row = re.split(r'\s+', line.rstrip('\n')) smpl = row[0] if len(row)==1: samples[smpl] = smpl else: samples[smpl] = row[1] if len(row)==3: grp = row[2] if grp in grp2sgn: grp = grp2sgn[grp] else: grp = '+' groups[smpl] = grp y = len(smpl2y) smpl2y[smpl] = y if highlight==None: groups = None return (samples,groups,smpl2y) plot_regions = parse_regions(plot_regions) (samples,groups,smpl2y) = parse_samples(sample_file,highlight) dat_gt = {} dat_rg = {} chrs = [] for fname in fnames: f = gzip.open(fname, 'rt') reader = csv.reader(f, 'tab') for row in reader: if row[0]=='GT': chr = row[1] pos = int(row[2]) reg = region_overlap(plot_regions,chr,pos,pos) if reg==None: continue for i in range(3,len(row),2): smpl = row[i] if samples!=None and smpl not in samples: continue gt = row[i+1] x = re.split(r'[/|]',gt) if x[0]=='.': continue # missing genotype ./. dsg = 2 if x[0]!=x[1]: dsg = 1 elif x[0]=='0': continue # skip HomRef 0/0 genotypes if chr not in dat_gt: dat_gt[chr] = {} chrs.append(chr) if smpl not in dat_gt[chr]: dat_gt[chr][smpl] = [] if smpl not in smpl2y: y = len(smpl2y) smpl2y[smpl] = y dat_gt[chr][smpl].append([pos,dsg]) elif row[0]=='RG': smpl = row[1] if samples!=None and smpl not in samples: continue chr = row[2] beg = int(row[3]) end = int(row[4]) length= int(row[5]) nmark = int(row[6]) qual = float(row[7]) if length < min_length: continue if nmark < min_markers : continue if qual < min_qual : continue reg = region_overlap(plot_regions,chr,beg,end) if reg==None: continue if chr not in dat_rg: dat_rg[chr] = {} if smpl not in dat_rg[chr]: dat_rg[chr][smpl] = [] if reg!=None: if begreg[1]: end = reg[1] dat_rg[chr][smpl].append([beg,end]) if samples==None: samples = {} for smpl in smpl2y: samples[smpl] = smpl # list the samples in the same order as encountered in the file, from top to bottom for smpl in smpl2y: smpl2y[smpl] = len(smpl2y) - smpl2y[smpl] - 1 off_list = [] off_hash = {} off = 0 off_sep = 0 dat_rg1 = {} if not chrs: usage("\nNo GT lines found in input file. Was it generated using the run-roh.pl script?\n" "This script is unable to process the raw output of \"bcftools roh\",\n" "the output of the following query may need to be added to the roh result.\n\n" "bcftools query -f'GT\\t%CHROM\\t%POS[\\t%SAMPLE\\t%GT]\\n' in.bcf\n") for chr in chrs: if chr in dat_rg: rg1 = merge_regions(dat_rg[chr]) if groups!=None: rg1 = prune_regions(groups,rg1) if len(rg1)!=0: dat_rg1[chr] = rg1 off_hash[chr] = off max_pos = 0 for smpl in dat_gt[chr]: if max_pos < dat_gt[chr][smpl][-1][0]: max_pos = dat_gt[chr][smpl][-1][0] if off_sep==0: off_sep = max_pos*0.1 off += max_pos + off_sep off_list.append(off) wh = track_width,len(smpl2y) if track_height < 0: wh = track_width,-track_height*len(smpl2y) elif len(smpl2y)>5: wh = track_width,5 def bignum(num): s = str(num); out = ''; slen = len(s) for i in range(slen): out += s[i] if i+1 x: break off = off_list[i] return 'chr%s:%s'%(chr,bignum(int(x - off))) fig, ax1 = plt.subplots(1, 1, figsize=wh, num=dir) ax1.yaxis.set_ticks_position('none') ax1.format_coord = format_coord xtick_lbl = [] xtick_pos = [] max_x = 0 min_x = -1 for chr in dat_gt: off = off_hash[chr] icol = 0 max = 0 for smpl in dat_gt[chr]: y = smpl2y[smpl] if chr in dat_rg and smpl in dat_rg[chr]: for rg in dat_rg[chr][smpl]: rect = patches.Rectangle((rg[0]+off,3*y+0.5), rg[1]-rg[0]+1, 2, color='#dddddd') ax1.add_patch(rect) if chr in dat_rg1 and smpl in dat_rg1[chr]: for rg in dat_rg1[chr][smpl]: rect = patches.Rectangle((rg[0]+off,3*y+0.5), rg[1]-rg[0]+1, 2, color='#d9534f') ax1.add_patch(rect) ax1.plot([x[0]+off for x in dat_gt[chr][smpl]],[x[1]+3*y for x in dat_gt[chr][smpl]],'.',color=cols[icol%len(cols)]) if min_x==-1 or min_x > dat_gt[chr][smpl][0][0]+off: min_x = dat_gt[chr][smpl][0][0]+off if max_x < dat_gt[chr][smpl][-1][0]+off: max_x = dat_gt[chr][smpl][-1][0]+off if max < dat_gt[chr][smpl][-1][0]: max = dat_gt[chr][smpl][-1][0] icol += 1 if icol >= len(cols): 0 xtick_lbl.append(chr) xtick_pos.append(off) ytick_lbl = [] ytick_pos = [] for chr in dat_gt: for smpl in dat_gt[chr]: ytick_lbl.append(samples[smpl]) ytick_pos.append(3*smpl2y[smpl]+1) break if xlim!=0: if min_x==-1: min_x = 0 ax1.set_xlim(min_x,max_x+xlim*max_x) lbl_pos = 3*(len(smpl2y)-1) ax1.annotate(' HomAlt ',xy=(max_x,lbl_pos-1),xycoords='data',va='center') ax1.annotate(' Het',xy=(max_x,lbl_pos-2),xycoords='data',va='center') if not show_xticks: ax1.set_xticks(xtick_pos) ax1.set_xticklabels(xtick_lbl) if xlabel!=None: ax1.set_xlabel(xlabel) ax1.set_yticks(ytick_pos) ax1.set_yticklabels(ytick_lbl) ax1.set_ylim(0,3*len(smpl2y)+0.5) plt.subplots_adjust(**adjust) if interactive: plt.show() else: files = parse_outfile(outfile) for file in (parse_outfile(outfile)): plt.savefig(file,dpi=dpi) plt.close() bcftools-1.21/misc/plot-vcfstats000077500000000000000000002601651467060157400167660ustar00rootroot00000000000000#!/usr/bin/env perl # # Plot the output of "bcftools stats -s -" # # The MIT License # # Copyright (C) 2012-2020 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. # Dependencies: # - matplotlib # http://matplotlib.sourceforge.net # - LaTex/xcolor.sty # Download .sty.gz LaTeX class style from http://www.ukern.de/tex/xcolor.html, # unpack and install system-wide or place elsewhere and make available by # setting the TEXINPUTS environment variable (note the colon) # export TEXINPUTS=some/dir: # The list of the recognised path can be obtained from `kpsepath tex` # # use strict; use warnings; use Carp; use Storable qw(dclone); my $opts = parse_params(); parse_vcfstats($opts); merge_vcfstats($opts) if @{$$opts{vcfstats}} > 1; chdir($$opts{dir}); if ( $$opts{make_plots} ) { init_plots($opts); plot_venn_bars($opts); plot_counts_by_AF($opts); plot_overlap_by_AF($opts); plot_concordance_by_AF($opts); plot_concordance_by_sample($opts); for my $id (file_ids($opts)) { plot_tstv_by_AF($opts,$id); plot_tstv_by_QUAL($opts,$id); plot_tstv_by_usr($opts,$id); plot_indel_distribution($opts,$id); plot_indel_vaf_distribution($opts,$id); plot_substitutions($opts,$id); plot_vaf($opts,$id,'snv'); plot_vaf($opts,$id,'indel'); plot_per_sample_stats($opts,$id); plot_DP($opts,$id); plot_hwe($opts,$id); plot_vaf25_by_sample($opts,$id,'snv'); plot_vaf25_by_sample($opts,$id,'indel'); } plot($opts); } create_pdf($opts) unless !$$opts{make_pdf}; exit; #-------------------------------- sub usage { print STDERR "About: Plots the output of \"bcftools stats\"\n", "Usage: plot-vcfstats [OPTIONS] -p outdir file.chk ...\n", "Options:\n", " -m, --merge Merge vcfstats files to STDOUT, skip plotting.\n", " -p, --prefix Output directory.\n", " -P, --no-PDF Skip the PDF creation step.\n", " -r, --rasterize Rasterize PDF images for fast rendering, the default and opposite of -v.\n", " -s, --sample-names Use sample names for xticks rather than numeric IDs.\n", " -t, --title Identify files by these titles in plots. Can be given multiple times.\n", " -T, --main-title Main title for the PDF.\n", " -v, --vectors Generate vector graphics for PDF images, the opposite of -r\n", " -h, -?, --help This help message.\n", "\n", "Example:\n", " # Generate the stats\n", " bcftools stats -s - > file.vchk\n", "\n", " # Plot the stats\n", " plot-vcfstats -p outdir file.vchk\n", "\n", " # The final looks can be customized by editing the generated\n", " # 'outdir/plot.py' script and re-running manually\n", " cd outdir && python3 plot.py && pdflatex summary.tex\n", "\n"; } sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } usage(); exit 1; } sub parse_params { $0 =~ s{^.+/}{}; my $opts = { usr_plots => [], use_sample_names => 0, verbose => 1, make_pdf => 1, make_plots => 1, merge => 0, args => join(' ',$0,@ARGV), img_fmt => 'png', img_width => 11/2.54, img_height => 10/2.54, id2col => [ 'orange', 'red', 'darkgreen' ], tex => { slide3v => { height1 => '7cm', height2 => '7cm', height3 => '4.5cm' }, slide3h => { width1 => '15cm', width2 => '10cm', width3 => '8cm' }, }, # for file version sanity check sections => [ { id=>'ID', header=>'Definition of sets', exp=>"# ID\t[2]id\t[3]tab-separated file names" }, { id=>'SN', header=>'SN, Summary numbers', exp=>"# SN\t[2]id\t[3]key\t[4]value" }, { id=>'TSTV', header=>'# TSTV, transition/transversions:', exp=>"# TSTV\t[2]id\t[3]ts\t[4]tv\t[5]ts/tv\t[6]ts (1st ALT)\t[7]tv (1st ALT)\t[8]ts/tv (1st ALT)" }, { id=>'SiS', header=>'Sis, Singleton stats', exp=>"# SiS\t[2]id\t[3]allele count\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable" }, { id=>'AF', header=>'AF, Stats by non-reference allele frequency', exp=>"# AF\t[2]id\t[3]allele frequency\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable" }, { id=>'IDD', header=>'IDD, InDel distribution', exp=>"# IDD\t[2]id\t[3]length (deletions negative)\t[4]number of sites\t[5]number of genotypes\t[6]mean VAF" }, { id=>'ST', header=>'ST, Substitution types', exp=>"# ST\t[2]id\t[3]type\t[4]count" }, { id=>'GCsAF', header=>'GCsAF, Genotype concordance by non-reference allele frequency (SNPs)', exp=>"# GCsAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes" }, { id=>'GCiAF', header=>'GCiAF, Genotype concordance by non-reference allele frequency (indels)', exp=>"# GCiAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes" }, { id=>'NRDs', header=>'Non-Reference Discordance (NRD), SNPs', exp=>"# NRDs\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance" }, { id=>'NRDi', header=>'Non-Reference Discordance (NRD), indels', exp=>"# NRDi\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance" }, { id=>'GCsS', header=>'GCsS, Genotype concordance by sample (SNPs)', exp=>"# GCsS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared" }, { id=>'GCiS', header=>'GCiS, Genotype concordance by sample (indels)', exp=>"# GCiS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared" }, { id=>'PSC', header=>'PSC, Per-sample counts', exp=>"# PSC\t[2]id\t[3]sample\t[4]nRefHom\t[5]nNonRefHom\t[6]nHets\t[7]nTransitions\t[8]nTransversions\t[9]nIndels\t[10]average depth\t[11]nSingletons\t[12]nHapRef\t[13]nHapAlt\t[14]nMissing" }, { id=>'PSI', header=>'PSI, Per-sample Indels', exp=>"# PSI\t[2]id\t[3]sample\t[4]in-frame\t[5]out-frame\t[6]not applicable\t[7]out/(in+out) ratio\t[8]nInsHets\t[9]nDelHets\t[10]nInsAltHoms\t[11]nDelAltHoms" }, { id=>'DP', header=>'DP, Depth distribution', exp=>"# DP\t[2]id\t[3]bin\t[4]number of genotypes\t[5]fraction of genotypes (%)\t[6]number of sites\t[7]fraction of sites (%)" }, { id=>'FS', header=>'FS, Indel frameshifts', exp=>"# FS\t[2]id\t[3]in-frame\t[4]out-frame\t[5]not applicable\t[6]out/(in+out) ratio\t[7]in-frame (1st ALT)\t[8]out-frame (1st ALT)\t[9]not applicable (1st ALT)\t[10]out/(in+out) ratio (1st ALT)" }, { id=>'ICS', header=>'ICS, Indel context summary', exp=>"# ICS\t[2]id\t[3]repeat-consistent\t[4]repeat-inconsistent\t[5]not applicable\t[6]c/(c+i) ratio" }, { id=>'ICL', header=>'ICL, Indel context by length', exp=>"# ICL\t[2]id\t[3]length of repeat element\t[4]repeat-consistent deletions)\t[5]repeat-inconsistent deletions\t[6]consistent insertions\t[7]inconsistent insertions\t[8]c/(c+i) ratio" }, { id=>'QUAL', header=>'QUAL, Stats by quality', exp=>"# QUAL\t[2]id\t[3]Quality\t[4]number of SNPs\t[5]number of transitions (1st ALT)\t[6]number of transversions (1st ALT)\t[7]number of indels" }, { id=>'HWE', header=>'HWE', exp=>"# HWE\t[2]id\t[3]1st ALT allele frequency\t[4]Number of observations\t[5]25th percentile\t[6]median\t[7]75th percentile", }, { id=>'VAF', header=>'VAF', exp=>"# VAF\t[2]id\t[3]sample\t[4]SNV VAF distribution\t[5]indel VAF distribution", }, ], SN_keys=>[ 'number of samples:', 'number of records:', 'number of no-ALTs:', 'number of SNPs:', 'number of MNPs:', 'number of indels:', 'number of others:', 'number of multiallelic sites:', 'number of multiallelic SNP sites:', ], }; for my $sec (@{$$opts{sections}}) { $$opts{exp}{$$sec{id}} = $$sec{exp}; $$opts{id2sec}{$$sec{id}} = $sec; } while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '--no-plots' ) { $$opts{make_plots}=0; next; } if ( $arg eq '-P' || $arg eq '--no-PDF' ) { $$opts{make_pdf}=0; next; } if ( $arg eq '-r' || $arg eq '--rasterize' ) { $$opts{img_fmt} = 'png'; next; } if ( $arg eq '-v' || $arg eq '--vectors' ) { $$opts{img_fmt} = 'pdf'; next; } if ( $arg eq '-m' || $arg eq '--merge' ) { $$opts{make_plots}=0; $$opts{make_pdf}=0; $$opts{merge}=1; next; } if ( $arg eq '-s' || $arg eq '--sample-names' ) { $$opts{use_sample_names}=1; next; } if ( $arg eq '-t' || $arg eq '--title' ) { push @{$$opts{titles}},shift(@ARGV); next; } if ( $arg eq '-T' || $arg eq '--main-title' ) { $$opts{main_title} = shift(@ARGV); next; } if ( $arg eq '-p' || $arg eq '--prefix' ) { $$opts{prefix}=shift(@ARGV); next; } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { usage(); exit 0; } if ( -e $arg ) { push @{$$opts{vcfstats}},$arg; next; } error("Unknown parameter or non-existent file \"$arg\". Run -h for help.\n"); } if ( !exists($$opts{vcfstats}) ) { error(); } if ( !exists($$opts{prefix}) ) { if ( !$$opts{merge} ) { error("Expected -p parameter.\n") } $$opts{prefix} = '.'; } elsif ( $$opts{merge} ) { error("Only one of -p or -m should be given.\n"); } if ( $$opts{merge} && @{$$opts{vcfstats}} < 2 ) { error("Nothing to merge\n") } $$opts{dir} = $$opts{prefix}; $$opts{logfile} = "plot-vcfstats.log"; if ( !-d $$opts{dir} ) { `mkdir -p $$opts{dir}`; } `> $$opts{dir}/$$opts{logfile}` unless $$opts{merge}; return $opts; } sub plot { my ($opts) = @_; if ( !exists($$opts{plt_fh}) ) { return; } close($$opts{plt_fh}) or error("close $$opts{plt_fh}"); my $cmd = "python3 $$opts{plt_file}"; print STDERR "Plotting graphs: $cmd\n" unless !$$opts{verbose}; system($cmd); if ( $? ) { error("The command exited with non-zero status $?:\n\t$cmd\n\n"); } } sub parse_vcfstats { my ($opts) = @_; for (my $i=0; $i<@{$$opts{vcfstats}}; $i++) { parse_vcfstats1($opts,$i); } # Check sanity if ( !exists($$opts{dat}{ID}{0}) ) { error("Sanity check failed: no stats found by vcfstats??\n"); } # Set titles my %file2title; my %title2file; if ( exists($$opts{titles}) ) { for (my $i=0; $i<@{$$opts{titles}}; $i++) { if ( !exists($$opts{dat}{ID}{$i}) ) { next; } $file2title{$$opts{dat}{ID}{$i}[0][0]} = $$opts{titles}[$i]; $title2file{$$opts{titles}[$i]} = $$opts{dat}{ID}{$i}[0][0]; } } for my $id (file_ids($opts)) { if ( @{$$opts{dat}{ID}{$id}[0]}>1 ) { next; } # shared stats of two files my $file = $$opts{dat}{ID}{$id}[0][0]; if ( !exists($file2title{$file}) ) # create short title { my $bname = $file; $bname =~ s{^.*/}{}; $bname =~ s{\.vcf\.gz$}{}i; if ( length($bname) > 5 ) { $bname = substr($bname,0,5); } my $i = 0; my $title = $bname; while ( exists($title2file{$title}) ) { $title = $bname.chr(66+$i); $i++; } $file2title{$file} = $title; $title2file{$title} = $file; } } for my $id (file_ids($opts)) { my @titles; for my $file (@{$$opts{dat}{ID}{$id}[0]}) { push @titles, $file2title{$file} if $file2title{$file}; } $$opts{title}{$id} = join(' + ',@titles); } # mapping from file names to list of IDs for my $id (file_ids($opts)) { my @files; for my $file (@{$$opts{dat}{ID}{$id}[0]}) { push @{$$opts{file2ids}{$file}}, $id; } } # check sanity of the file merge: were the correct files merged? if ( exists($$opts{coalesced_files}) && $$opts{verbose} ) { print STDERR "The vcfstats outputs have been merged as follows:\n"; my %printed; for my $id (keys %{$$opts{coalesced_files}}) { for (my $i=0; $i<@{$$opts{coalesced_files}{$id}}; $i++) { for (my $j=0; $j<@{$$opts{coalesced_files}{$id}[$i]}; $j++) { if ( exists($printed{$$opts{dat}{ID}{$id}[$i][$j]}) ) { next; } print STDERR "\t$$opts{dat}{ID}{$id}[$i][$j]\n"; for my $file (keys %{$$opts{coalesced_files}{$id}[$i][$j]}) { my $n = $$opts{coalesced_files}{$id}[$i][$j]{$file}; print STDERR "\t\t$file", ($n>1 ? "\t..\t${n}x" : ''),"\n"; } $printed{$$opts{dat}{ID}{$id}[$i][$j]} = 1; } } } } } sub add_to_values { my ($dst,$src,$cmp) = @_; my $id = 0; my $is = 0; while ($is<@$src) { while ( $id<@$dst && &$cmp($$src[$is][0],$$dst[$id][0])>0 ) { $id++; } if ( $id<@$dst && !&$cmp($$src[$is][0],$$dst[$id][0]) ) { for (my $j=1; $j<@{$$src[$is]}; $j++) { if ( $$dst[$id][$j] eq '.' or $$src[$is][$j] eq '.' ) { next; } $$dst[$id][$j] += $$src[$is][$j]; } } else { splice(@$dst,$id,0,$$src[$is]); } $is++; } } sub add_to_sample_values { my ($dst,$src) = @_; my %id2i; for (my $i=0; $i<@$dst; $i++) { $id2i{$$dst[$i][0]} = $i; } for (my $i=0; $i<@$src; $i++) { if ( !exists($id2i{$$src[$i][0]}) ) { error("Whoops, no such dst sample: $$src[$i][0]\n"); } my $di = $id2i{$$src[$i][0]}; for (my $j=1; $j<@{$$src[$i]}; $j++) { $$dst[$di][$j] += $$src[$i][$j]; } } } sub merge_PSC { my ($a,$b,$n) = @_; for (my $i=0; $i<@$a; $i++) { $$a[$i][7] *= $n; } # average DP add_to_sample_values($a,$b); for (my $i=0; $i<@$a; $i++) { $$a[$i][7] /= $n+1; } } sub merge_PSI { my ($a,$b,$n) = @_; add_to_sample_values($a,$b); for (my $i=0; $i<@$b; $i++) { $$a[$i][4] = sprintf "%.2f", ($$a[$i][1]+$$a[$i][2] ? $$a[$i][2]/($$a[$i][1]+$$a[$i][2]) : 0); } } sub rglob { my ($a,$b) = @_; if ( $a eq $b ) { return $a; } $a =~ s/\*//; my $la = length($a); my $lb = length($b); my $i = 0; while ( $i<$la && $i<$lb && substr($a,$i,1) eq substr($b,$i,1) ) { $i++; } $la--; $lb--; while ( $la>$i && $lb>$i && substr($a,$la,1) eq substr($b,$lb,1) ) { $la--; $lb--; } $la = $la==$i && $lb==$i ? 1 : $la-$i; substr($a,$i,$la,'*'); return $a; } sub merge_id { # merge id filenames my ($opts,$dst,$src,$id) = @_; for (my $i=0; $i<@{$$src{$id}}; $i++) { for (my $j=0; $j<@{$$src{$id}[$i]}; $j++) { my $gname = rglob($$dst{$id}[$i][$j], $$src{$id}[$i][$j]); $$dst{$id}[$i][$j] = $gname; $$opts{coalesced_files}{$id}[$i][$j]{$$src{$id}[$i][$j]}++; } } } sub add_to_avg { my ($dst,$src,$n) = @_; for (my $i=0; $i<@$src; $i++) { if ( ref($$dst[$i]) eq 'ARRAY' ) { for (my $j=0; $j<@{$$dst[$i]}; $j++) { $$dst[$i][$j] = ($n*$$dst[$i][$j]+$$src[$i][$j])/($n+1); } } else { $$dst[$i] = ($n*$$dst[$i]+$$src[$i])/($n+1); } } } sub cmp_str($$) { my ($a,$b) = @_; return $a cmp $b; } sub cmp_num($$) { my ($a,$b) = @_; return $a <=> $b; } sub cmp_num_op($$) { # numeric compare with operators # Cases like <3, >500 make it complicated my ($a,$b) = @_; my $xa = '='; my $xb = '='; if ( $a=~/^(\D+)/ ) { $xa = $1; $a = $'; } if ( $b=~/^(\D+)/ ) { $xb = $1; $b = $'; } if ( $a==$b ) { return $xa cmp $xb; } $a <=> $b; } sub merge_dp { my ($a,$b) = @_; add_to_values($a,$b,\&cmp_num_op); # recalculate fraction of GTs and fraction of sites, cannot be simply summed my $gsum = 0; # genotype sum my $ssum = 0; # site sum for (my $i=0; $i<@$a; $i++) { $gsum += $$a[$i][1]; if (@{$$a[$i]}>3) { $ssum += $$a[$i][3]; } else{ push @{$$a[$i]}, (0,0); # older stats files will not have last 2 columns for (number of sites, fraction of sites), so fill in as zero } } for (my $i=0; $i<@$a; $i++) { $$a[$i][2] = $gsum ? $$a[$i][1]*100./$gsum : 0; $$a[$i][4] = $ssum ? $$a[$i][3]*100./$ssum : 0; } } sub merge_GCsS { my ($a,$b,$n) = @_; # average the non-ref discordance rate for (my $i=0; $i<@$a; $i++) { $$a[$i][1] *= $n; } add_to_sample_values($a,$b); for (my $i=0; $i<@$a; $i++) { $$a[$i][1] /= $n+1; } } sub merge_FS { my ($a,$b) = @_; for (my $i=0; $i<@$a; $i++) { for (my $j=0; $j<3; $j++) { $$a[$i][$j] += $$b[$i][$j]; } $$a[$i][3] = sprintf "%.2f", ($$a[$i][0] + $$a[$i][1]) ? $$a[$i][1]/($$a[$i][0] + $$a[$i][1]) : 0; for (my $j=4; $j<7; $j++) { $$a[$i][$j] += $$b[$i][$j]; } $$a[$i][7] = sprintf "%.2f", ($$a[$i][4] + $$a[$i][5]) ? $$a[$i][5]/($$a[$i][4] + $$a[$i][5]) : 0; } } sub merge_ICS { my ($a,$b) = @_; for (my $i=0; $i<@$a; $i++) { for (my $j=0; $j<3; $j++) { $$a[$i][$j] += $$b[$i][$j]; } $$a[$i][3] = sprintf "%.4f", ($$a[$i][0] + $$a[$i][1]) ? $$a[$i][0]/($$a[$i][0] + $$a[$i][1]) : 0; } } sub merge_ICL { my ($a,$b) = @_; for (my $i=0; $i<@$a; $i++) { for (my $j=1; $j<5; $j++) { $$a[$i][$j] += $$b[$i][$j]; } $$a[$i][5] = sprintf "%.4f", ($$a[$i][2] + $$a[$i][4]) ? ($$a[$i][1] + $$a[$i][3])/($$a[$i][1] + $$a[$i][2] + $$a[$i][3] + $$a[$i][4]) : 0; } } sub merge_TSTV { my ($a,$b) = @_; for (my $i=0; $i<@$a; $i++) { for (my $j=0; $j<2; $j++) { $$a[$i][$j] += $$b[$i][$j]; } $$a[$i][2] = sprintf "%.2f", $$a[$i][1] ? $$a[$i][0]/$$a[$i][1] : 0; for (my $j=3; $j<5; $j++) { $$a[$i][$j] += $$b[$i][$j]; } $$a[$i][5] = sprintf "%.2f", $$a[$i][4] ? $$a[$i][3]/$$a[$i][4] : 0; } } sub merge_GCsAF { my ($a,$b) = @_; # recalculate r2 for (my $i=0; $i<@$a; $i++) { $$a[$i][7] *= $$a[$i][8]; } for (my $i=0; $i<@$b; $i++) { $$b[$i][7] *= $$b[$i][8]; } add_to_values($a,$b,\&cmp_num_op); for (my $i=0; $i<@$a; $i++) { $$a[$i][7] /= $$a[$i][8]; } } sub merge_HWE { my ($dst,$src) = @_; # The fields are: # [0] - AF of the 1st ALT # [1] - number of observations # [2] - 25th percentile # [3] - median # [4] - 75th percentile # # It is impossible to do the proper merge without source data, hence # an approximation: take average of the percentiles weighted by the # number of observations my $id = 0; my $is = 0; while ($is<@$src) { while ( $id<@$dst && $$src[$is][0] > $$dst[$id][0] ) { $id++; } if ( $id<@$dst && $$src[$is][0] == $$dst[$id][0] ) { my $sw = $$src[$is][1]+$$dst[$id][1] ? $$src[$is][1]/($$src[$is][1]+$$dst[$id][1]) : 0; my $dw = $$src[$is][1]+$$dst[$id][1] ? $$dst[$id][1]/($$src[$is][1]+$$dst[$id][1]) : 0; for (my $j=2; $j<@{$$src[$is]}; $j++) { if ( $$dst[$id][$j] eq '.' or $$src[$is][$j] eq '.' ) { next; } $$dst[$id][$j] = $dw*$$dst[$id][$j] + $sw*$$src[$is][$j]; } $$dst[$id][1] += $sw*$$src[$is][1]; } else { splice(@$dst,$id,0,$$src[$is]); } $is++; } } sub parse_vcfstats1 { my ($opts,$i) = @_; my $file = $$opts{vcfstats}[$i]; print STDERR "Parsing bcftools stats output: $file\n" unless !$$opts{verbose}; open(my $fh,'<',$file) or error("$file: $!"); my $line = <$fh>; if ( !$line or !($line=~/^# This file was produced by \S*/) ) { error("Sanity check failed: was this file generated by bcftools stats?"); } my %dat; while ($line=<$fh>) { $line =~ s/\s*$//; if ( $line=~/^#\s+(\S+)\t/ ) { $$opts{def_line}{$1} = $line; next; } if ( $line=~/^#/ ) { next; } my @items = split(/\t/,$line); if ( $items[0] eq 'SN' ) { $dat{$items[1]}{$items[2]} = splice(@items,3); next; } push @{$dat{$items[0]}{$items[1]}}, [splice(@items,2)]; } close($fh); for my $a (keys %dat) { if ( !exists($$opts{dat}{$a}) ) { $$opts{dat}{$a} = $dat{$a}; next; } # first vcfstats file for my $b (keys %{$dat{$a}}) { # Merging multiple vcfstats files. Honestly, this is quite hacky. if ( !exists($$opts{dat}{$a}{$b}) ) { $$opts{dat}{$a}{$b} = $dat{$a}{$b}; next; } # copy all, first occurrence if ( $a eq 'ID' ) { merge_id($opts,$$opts{dat}{$a},$dat{$a},$b); } elsif ( ref($dat{$a}{$b}) ne 'ARRAY' ) { $$opts{dat}{$a}{$b} += $dat{$a}{$b} unless $b eq 'number of samples:'; } # SN, Summary numbers, do not sum sample counts elsif ( $a eq 'NRDs' ) { add_to_avg($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'NRDi' ) { add_to_avg($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'DP' ) { merge_dp($$opts{dat}{$a}{$b},$dat{$a}{$b}); } elsif ( $a eq 'GCsS' ) { merge_GCsS($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'GCiS' ) { merge_GCsS($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'GCsAF' ) { merge_GCsAF($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'GCiAF' ) { merge_GCsAF($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'HWE' ) { merge_HWE($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'ST' ) { add_to_values($$opts{dat}{$a}{$b},$dat{$a}{$b},\&cmp_str); } elsif ( $a eq 'PSC') { merge_PSC($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'PSI') { merge_PSI($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'IDD') { add_to_values($$opts{dat}{$a}{$b},$dat{$a}{$b},\&cmp_num); } elsif ( $a eq 'FS') { merge_FS($$opts{dat}{$a}{$b},$dat{$a}{$b}); } elsif ( $a eq 'ICS') { merge_ICS($$opts{dat}{$a}{$b},$dat{$a}{$b}); } elsif ( $a eq 'ICL') { merge_ICL($$opts{dat}{$a}{$b},$dat{$a}{$b}); } elsif ( $a eq 'TSTV') { merge_TSTV($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } elsif ( $a eq 'DBG' ) { next; } else { add_to_values($$opts{dat}{$a}{$b},$dat{$a}{$b},\&cmp_num_op); } # SiS AF IDD } } } sub file_ids { my ($opts) = @_; my $id = 0; my @out; while ( exists($$opts{dat}{ID}) && exists($$opts{dat}{ID}{$id}) ) { push @out, $id++; } return @out; } sub tprint { my ($fh,$text) = @_; my @lines = split(/\n/,$text); my $ntab; for my $line (@lines) { if ( !defined $ntab ) { if ( $line=~/^\s*$/ ) { print $fh $line; next; } $ntab = ( $line=~/^\s+/ ) ? length($&) : 0; } if ( $line=~/^\s{$ntab}/ ) { substr($line,0,$ntab,''); } print $fh $line."\n"; } } sub init_plots { my ($opts) = @_; $$opts{plt_file} = "plot.py"; my $titles = "# Title abbreviations:\n"; for my $id (file_ids($opts)) { $titles .= "# \t $id .. $$opts{title}{$id} .. $$opts{dat}{ID}{$id}[0][0]\n"; } $titles .= "#"; open(my $fh,'>',$$opts{plt_file}) or error("$$opts{plt_file}: $!"); tprint $fh, qq[ # This file was produced by plot-vcfstats, the command line was: # $$opts{args} # # Edit as necessary and recreate the plots by running # python3 $$opts{plt_file} # $titles img_fmt = '$$opts{img_fmt}' # Use logarithmic X axis for allele frequency plots af_xlog = 0 # Plots to generate, set to 0 to disable plot_venn_snps = 1 plot_venn_indels = 1 plot_tstv_by_sample = 1 plot_hethom_by_sample = 1 plot_snps_by_sample = 1 plot_indels_by_sample = 1 plot_singletons_by_sample = 1 plot_depth_by_sample = 1 plot_SNP_count_by_af = 1 plot_Indel_count_by_af = 1 plot_SNP_overlap_by_af = 1 plot_Indel_overlap_by_af = 1 plot_dp_dist = 1 plot_hwe = 1 plot_concordance_by_af = 1 plot_r2_by_af = 1 plot_discordance_by_sample = 1 plot_tstv_by_af = 1 plot_indel_dist = 1 plot_indel_vaf = 1 plot_tstv_by_qual = 1 plot_tstv_by_usr = 1 plot_substitutions = 1 plot_vaf_snv = 1 plot_vaf_indel = 1 plot_vaf25_snv = 1 plot_vaf25_indel = 1 # Set to 1 to use sample names for xticks instead of numeric sequential IDs # and adjust margins and font properties if necessary sample_names = $$opts{use_sample_names} sample_margins = {'right':0.98, 'left':0.07, 'bottom':0.2} sample_font = {'rotation':45, 'ha':'right', 'fontsize':8} if sample_names==0: sample_margins=(); sample_font=(); #------------------------------------------------- import matplotlib as mpl mpl.use('Agg') import matplotlib.pyplot as plt import csv csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE) import numpy def smooth(x,window_len=11,window='hanning'): if x.ndim != 1: raise ValueError("The function 'smooth' only accepts 1 dimension arrays.") if x.size < window_len: return x if window_len<3: return x if not window in ['flat', 'hanning', 'hamming', 'bartlett', 'blackman']: raise ValueError("Window is on of 'flat', 'hanning', 'hamming', 'bartlett', 'blackman'") s = numpy.r_[x[window_len-1:0:-1],x,x[-1:-window_len:-1]] if window == 'flat': # moving average w = numpy.ones(window_len,'d') else: w = eval('numpy.'+window+'(window_len)') y = numpy.convolve(w/w.sum(),s,mode='valid') return y[(window_len//2-1):-(window_len//2)] ]; $$opts{plt_fh} = $fh; } sub percentile { my ($p,@vals) = @_; my $N = 0; for my $val (@vals) { $N += $val; } my $n = $p*($N+1)/100.; my $k = int($n); my $d = $n-$k; if ( $k<=0 ) { return 0; } if ( $k>=$N ) { return scalar @vals-1; } my $cnt; for (my $i=0; $i<@vals; $i++) { $cnt += $vals[$i]; if ( $cnt>=$k ) { return $i; } } error("FIXME: this should not happen [percentile]\n"); } sub get_values { my ($opts,$id,$key,$i,$j) = @_; if ( !exists($$opts{dat}{$key}) ) { return (); } if ( !exists($$opts{dat}{$key}{$id}) ) { return (); } my $fields_ok = 1; if ( !exists($$opts{exp}{$key}) && !($key=~/^USR:/) ) { error("todo: sanity check for $key\n"); } if ( exists($$opts{def_line}{$key}) && !($key=~/^USR:/) && $$opts{def_line}{$key} ne $$opts{exp}{$key} && !$$opts{def_line_warned}{$key} ) { warn("Warning: Possible version mismatch, the definition line differs\n\texpected: $$opts{exp}{$key}\n\tfound: $$opts{def_line}{$key}\n"); $$opts{def_line_warned}{$key} = 1; } if ( defined $i ) { if ( defined $j ) { return $$opts{dat}{$key}{$id}[$i][$j]; } return (@{$$opts{dat}{$key}{$id}[$i]}); } return (@{$$opts{dat}{$key}{$id}}); } sub get_value { my ($opts,$id,$key) = @_; if ( !exists($$opts{dat}{$id}) ) { return undef; } if ( !exists($$opts{dat}{$id}{$key}) ) { return undef} return $$opts{dat}{$id}{$key}; } sub plot_venn_bars { my ($opts) = @_; my @ids = file_ids($opts); if ( @ids != 3 ) { return; } my (@snps,@indels,@tstv,@snp_titles,@indel_titles); for my $id (0..2) { push @snps, get_value($opts,$id,'number of SNPs:'); push @indels, get_value($opts,$id,'number of indels:'); push @tstv, sprintf("%.2f",get_values($opts,$id,'TSTV',0,5)); push @snp_titles, "$$opts{title}{$id}\\nts/tv $tstv[$id]\\n" .bignum($snps[$id]); my @fs = get_values($opts,$id,'FS'); my $fs = @fs ? "frm $fs[0][3]\\n" : ''; push @indel_titles, "$$opts{title}{$id}\\n$fs" .bignum($indels[$id]); } my $fh = $$opts{plt_fh}; tprint $fh, qq[ if plot_venn_snps: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.bar([1,2,3],[$snps[0],$snps[2],$snps[1]],align='center',color='$$opts{id2col}[0]',width=0.3) ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') ax1.set_xlim(0.5,3.5) plt.xticks([1,2,3],('$snp_titles[0]','$snp_titles[2]','$snp_titles[1]')) plt.title('Number of SNPs') plt.subplots_adjust(right=0.95,bottom=0.15) plt.savefig('venn_bars.snps.png') if img_fmt != 'png': plt.savefig('venn_bars.snps.' + img_fmt) plt.close() if plot_venn_indels: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.bar([1,2,3],[$indels[0],$indels[2],$indels[1]],align='center',color='$$opts{id2col}[1]',width=0.3) ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') ax1.set_xlim(0.5,3.5) plt.xticks([1,2,3],('$indel_titles[0]','$indel_titles[2]','$indel_titles[1]')) plt.title('Number of indels') plt.subplots_adjust(right=0.95,bottom=0.15) plt.savefig('venn_bars.indels.png') if img_fmt != 'png': plt.savefig('venn_bars.indels.' + img_fmt) plt.close() ]; } sub plot_per_sample_stats { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'PSC'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "tstv_by_sample.$id"; my $img2 = "hets_by_sample.$id"; my $img3 = "snps_by_sample.$id"; my $img4 = "indels_by_sample.$id"; my $img5 = "singletons_by_sample.$id"; my $img6 = "dp_by_sample.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Sample ID\t[2]ts/tv\t[3]het/hom\t[4]nSNPs\t[5]nIndels\t[6]Average depth\t[7]nSingletons\t[8]Sample name\n"; for (my $i=0; $i<@vals; $i++) { my $tstv = $vals[$i][5] ? $vals[$i][4]/$vals[$i][5] : 0; my $hethom = $vals[$i][2] ? $vals[$i][3]/$vals[$i][2] : 0; printf $tfh "%d\t%f\t%f\t%d\t%d\t%f\t%d\t%s\n", $i, $tstv, $hethom, $vals[$i][4]+$vals[$i][5], $vals[$i][6], $vals[$i][7], $vals[$i][8], $vals[$i][0]; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row[:7]] + [row[7]]) if plot_tstv_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[1] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('Ts/Tv') ax1.set_ylim(min(float(row[1]) for row in dat)-0.1,max(float(row[1]) for row in dat)+0.1) if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() if plot_hethom_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[2] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('nHet(RA) / nHom(AA)') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.title('$$opts{title}{$id}') plt.savefig('$img2.png') if img_fmt != 'png': plt.savefig('$img2.' + img_fmt) plt.close() if plot_snps_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[3] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('Number of SNPs') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.title('$$opts{title}{$id}') plt.savefig('$img3.png') if img_fmt != 'png': plt.savefig('$img3.' + img_fmt) plt.close() if plot_indels_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[4] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('Number of indels') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.title('$$opts{title}{$id}') plt.savefig('$img4.png') if img_fmt != 'png': plt.savefig('$img4.' + img_fmt) plt.close() if plot_singletons_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[6] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('Number of singletons') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.title('$$opts{title}{$id}') plt.savefig('$img5.png') if img_fmt != 'png': plt.savefig('$img5.' + img_fmt) plt.close() if plot_depth_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[5] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('Average depth') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.title('$$opts{title}{$id}') plt.savefig('$img6.png') if img_fmt != 'png': plt.savefig('$img6.' + img_fmt) plt.close() "; } sub plot_DP { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'DP'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "depth.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Depth\t[2]Cumulative number of genotypes\t[3]Number of genotypes\n"; my $sum = 0; for (my $i=0; $i<@vals; $i++) { if ( $sum>99. ) { last; } if ( !($vals[$i][0]=~/^\d+$/) ) { next; } # DP ">500" case $sum += $vals[$i][2]; printf $tfh "%d\t%f\t%f\n", $vals[$i][0], $sum, $vals[$i][2]; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row]) if plot_dp_dist: fig = plt.figure(figsize=($$opts{img_width}*1.2,$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[2] for row in dat], '-^', color='k') ax1.set_ylabel('Number of genotypes [%]',color='k') ax1.set_xlabel('Depth') ax2 = ax1.twinx() ax2.plot([row[0] for row in dat], [row[1] for row in dat], '-o', color='$$opts{id2col}[$id]') ax2.set_ylabel('Cumulative number of genotypes [%]',color='$$opts{id2col}[$id]') for tl in ax2.get_yticklabels(): tl.set_color('$$opts{id2col}[$id]') plt.subplots_adjust(left=0.2,bottom=0.15,right=0.8) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_hwe { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'HWE'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "hwe.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Allele Frequency\t[2]Depth\t[3]Number of hets (median)\t[4]Number of hets (25-75th percentile)\n"; for (my $i=0; $i<@vals; $i++) { if ( !$vals[$i][1] ) { next; } print $tfh join("\t", @{$vals[$i]}), "\n"; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append(row) if plot_hwe and len(dat)>1: x = [float(row[0]) for row in dat] y1 = smooth(numpy.array([float(row[2]) for row in dat]),40,'hanning') y2 = smooth(numpy.array([float(row[3]) for row in dat]),40,'hanning') y3 = smooth(numpy.array([float(row[4]) for row in dat]),40,'hanning') dp = smooth(numpy.array([float(row[1]) for row in dat]),40,'hanning') hwe = [] for af in x: hwe.append(2*af*(1-af)) fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) plots = ax1.plot(x,hwe,'--',color='#ff9900',label='Expected (HWE)') plots += ax1.plot(x,y2,color='#ff9900',label='Median') plots += ax1.plot(x,y3,color='#ffe0b2',label='25-75th percentile') ax1.fill_between(x,y1,y3, facecolor='#ffeacc',edgecolor='#ffe0b2') ax1.set_ylabel('Fraction of hets',color='#ff9900') ax1.set_xlabel('Allele frequency') for tl in ax1.get_yticklabels(): tl.set_color('#ff9900') ax2 = ax1.twinx() plots += ax2.plot(x,dp, 'k', label='Number of sites') ax2.set_ylabel('Number of sites') ax2.set_yscale('log') if af_xlog: ax1.set_xscale('log') if af_xlog: ax2.set_xscale('log') labels = [l.get_label() for l in plots] plt.legend(plots,labels,numpoints=1,markerscale=2,loc='center',prop={'size':9},frameon=False) plt.subplots_adjust(left=0.15,bottom=0.15,right=0.86) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_tstv_by_AF { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'AF'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "tstv_by_af.$id"; my $vals = rebin_values(\@vals,8,0); open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Allele frequency\t[2]Number of sites\t[3]ts/tv\n"; for (my $i=0; $i<@$vals; $i++) { if ( $$vals[$i][2] + $$vals[$i][3] == 0 ) { next; } printf $tfh "%f\t%d\t%f\n", $$vals[$i][0], $$vals[$i][2] + $$vals[$i][3], $$vals[$i][3] ? $$vals[$i][2]/$$vals[$i][3]: 0; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row]) if plot_tstv_by_af and len(dat)>2: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[1] for row in dat], '-o',color='k',mec='k',markersize=3) ax1.set_ylabel('Number of sites',color='k') ax1.set_yscale('log') #ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') for tl in ax1.get_yticklabels(): tl.set_color('k') ax1.set_xlabel('Non-ref allele frequency') ax2 = ax1.twinx() ax2.plot([row[0] for row in dat], [row[2] for row in dat], '-o',color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]',markersize=3) ax2.set_ylabel('Ts/Tv',color='$$opts{id2col}[$id]') ax2.set_ylim(0,0.5+max(3,max(row[2] for row in dat))) ax1.set_xlim(0,1) for tl in ax2.get_yticklabels(): tl.set_color('$$opts{id2col}[$id]') plt.subplots_adjust(right=0.88,left=0.15,bottom=0.11) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } # Sort calls by quality and plot ts/tv in bins of reasonable size (1%); # Plot both cumulative ts/tv (as if quality threshold was applied at that point) # and per bin. sub plot_tstv_by_QUAL { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'QUAL'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "tstv_by_qual.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Quality\t[2]Number of sites\t[3]Marginal Ts/Tv\n"; my @dat = (); my $ntot = 0; for my $val (@vals) { if ( $$val[0] eq '.' ) { next; } push @dat, [ $$val[0], $$val[2], $$val[3] ]; # qual, nts, ntv $ntot += $$val[2] + $$val[3]; } my @sdat = sort { $$b[0] <=> $$a[0] } @dat; push @sdat, [-1]; my $dn = $ntot*0.01; my $qprev = $sdat[0][0]; my $nout = 0; my $nts = 0; my $ntv = 0; my $nts_tot = 0; my $ntv_tot = 0; for my $rec (@sdat) # sorted in descendent order, biggest qualities come first { if ( $$rec[0]==-1 or $nts+$ntv > $dn ) { if ( $ntv ) { printf $tfh "$qprev\t%d\t%f\t%f\n", $nts+$ntv+$nout,$nts/$ntv,$nts_tot/$ntv_tot; } if ( $$rec[0]==-1 ) { last; } $nout += $nts+$ntv; $nts = 0; $ntv = 0; $qprev = $$rec[0]; } $nts += $$rec[1]; $ntv += $$rec[2]; $nts_tot += $$rec[1]; $ntv_tot += $$rec[2]; } close($tfh) or error("close $img.dat"); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row]) if plot_tstv_by_qual and len(dat)>2: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.plot([row[1] for row in dat], [row[3] for row in dat], '-', ms=1, mec='$$opts{id2col}[$id]', color='$$opts{id2col}[$id]', label='Cumulative ts/tv') ax1.plot([row[1] for row in dat], [row[2] for row in dat], '--', ms=1, mec='$$opts{id2col}[$id]', color='$$opts{id2col}[$id]', label='Per 1% bins') ax1.set_ylabel('Ts/Tv',fontsize=10) ax1.set_xlabel('Number of sites\\n(sorted by QUAL, descending)',fontsize=10) ax1.ticklabel_format(style='sci', scilimits=(-3,2), axis='x') ax1.set_ylim(min(2,min(row[2] for row in dat))-0.3,0.3+max(2.2,max(row[2] for row in dat))) plt.legend(numpoints=1,markerscale=2,loc='best',prop={'size':9},frameon=False) plt.subplots_adjust(right=0.88,left=0.15,bottom=0.15) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_tstv_by_usr { my ($opts,$id) = @_; for my $key (keys %{$$opts{dat}}) { if ( !($key=~/^USR:/) ) { next; } plot_tstv_by_usr1($opts,$id,$key); } } sub plot_tstv_by_usr1 { my ($opts,$id,$name) = @_; my @vals = get_values($opts,$id,$name); if ( !@vals ) { return; } my $fname = $name; $fname =~ s{/}{_}g; push @{$$opts{usr_plots}},{fname=>"tstv_by_$fname",uname=>$name}; my $fh = $$opts{plt_fh}; my $img = "tstv_by_$fname.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]$name\t[2]Number of sites\t[3]Marginal Ts/Tv\n"; for my $rec (@vals) { my ($val,$nts,$ntv,undef) = @$rec; if ( $nts+$ntv==0 ) { next; } printf $tfh "$val\t%d\t%f\n", $nts+$ntv,$ntv?$nts/$ntv:0; } close($tfh) or error("close $img.dat"); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row]) if plot_tstv_by_usr and len(dat)>2: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) ax2 = ax1.twinx() plots = ax1.plot([row[0] for row in dat], [row[2] for row in dat], 'o', mec='$$opts{id2col}[$id]', color='$$opts{id2col}[$id]') plots += ax2.plot([row[0] for row in dat], [row[1] for row in dat], 'o', mec='grey', color='grey') ax1.set_ylabel('Ts/Tv',fontsize=10) ax2.set_ylabel('Number of sites',fontsize=10) ax1.set_xlabel('$name',fontsize=10) ax1.ticklabel_format(style='sci', scilimits=(-3,2), axis='x') ax2.ticklabel_format(style='sci', scilimits=(-2,2), axis='y') ax1.set_ylim(min(2,min(row[2] for row in dat))-0.3,0.3+max(2.2,max(row[2] for row in dat))) labels = ['ts/tv','Number of sites'] plt.legend(plots,labels,numpoints=1,loc='best',prop={'size':9},frameon=False) plt.subplots_adjust(right=0.88,left=0.15,bottom=0.15) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub rebin_values { my ($vals,$bin_size,$col,%args) = @_; my %avg = exists($args{avg}) ? map {$_=>1} @{$args{avg}} : (); my $prev = $$vals[0][$col]; my $iout = 0; my $nsum = 0; my (@dat,@out); for (my $i=0; $i<@$vals; $i++) { for (my $icol=0; $icol<@{$$vals[$i]}; $icol++) { if ( $icol==$col ) { next; } $dat[$icol] += $$vals[$i][$icol]; } $nsum++; if ( $i+1<@$vals && $$vals[$i][$col] - $prev < $bin_size ) { next; } $dat[$col] = $prev; for (my $icol=0; $icol<@{$$vals[$i]}; $icol++) { $out[$iout][$icol] = $dat[$icol] ? $dat[$icol] : 0; if ( $avg{$icol} && $nsum ) { $out[$iout][$icol] /= $nsum; } } $nsum = 0; @dat = (); $iout++; $prev = $$vals[$i][$col]; } return \@out; } sub plot_concordance_by_AF { my ($opts) = @_; my @vals = get_values($opts,2,'GCsAF'); if ( !@vals ) { return; } # create a local copy and prepare r2 for rebinning @vals = @{ dclone(\@vals) }; for (my $i=0; $i<@vals; $i++) { $vals[$i][7] *= $vals[$i][8]; } my $vals = rebin_values(\@vals,0.01,0); my $fh = $$opts{plt_fh}; my $img = "gts_by_af"; my $img2 = "r2_by_af"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Allele Frequency\t[2]RR concordance\t[3]RA concordance\t[4]AA concordance\t[5]nRR\t[6]nRA\t[7]nAA\t[8]R^2\t[9]Number of genotypes\n"; for (my $i=0; $i<@$vals; $i++) { printf $tfh "%f\t%f\t%f\t%f\t%d\t%d\t%d\t%f\t%d\n", $$vals[$i][0], $$vals[$i][1]+$$vals[$i][4] ? $$vals[$i][1]/($$vals[$i][1]+$$vals[$i][4]) : 1, $$vals[$i][2]+$$vals[$i][5] ? $$vals[$i][2]/($$vals[$i][2]+$$vals[$i][5]) : 1, $$vals[$i][3]+$$vals[$i][6] ? $$vals[$i][3]/($$vals[$i][3]+$$vals[$i][6]) : 1, $$vals[$i][1]+$$vals[$i][4], $$vals[$i][2]+$$vals[$i][5], $$vals[$i][3]+$$vals[$i][6], $$vals[$i][8] ? $$vals[$i][7]/$$vals[$i][8] : 1, $$vals[$i][8]; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append(row) if plot_concordance_by_af and len(dat)>1: fig = plt.figure(figsize=($$opts{img_width}*1.2,$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[1] for row in dat],'.',color='$$opts{id2col}[1]',label='Hom RR') ax1.plot([row[0] for row in dat], [row[2] for row in dat],'.',color='$$opts{id2col}[0]',label='Het RA') ax1.plot([row[0] for row in dat], [row[3] for row in dat],'.',color='k',label='Hom AA') ax1.set_xlabel('Non-ref allele frequency') ax1.set_ylabel('Concordance') leg = ax1.legend(title='Concordance:',numpoints=1,markerscale=2,loc='best',prop={'size':9}) leg.draw_frame(False) plt.setp(leg.get_title(),fontsize=9) ax2 = ax1.twinx() ax2.plot([row[0] for row in dat], [row[4] for row in dat],color='$$opts{id2col}[1]') ax2.plot([row[0] for row in dat], [row[5] for row in dat],color='$$opts{id2col}[0]') ax2.plot([row[0] for row in dat], [row[6] for row in dat],color='k') ax2.set_ylabel('Number of genotypes') ax2.set_yscale('log') if af_xlog: ax1.set_xscale('log') if af_xlog: ax2.set_xscale('log') plt.subplots_adjust(left=0.15,right=0.83,bottom=0.11) plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() if plot_r2_by_af and len(dat)>1: fig = plt.figure(figsize=($$opts{img_width}*1.3,$$opts{img_height})) ax1 = fig.add_subplot(111) ax2 = ax1.twinx() ax1.set_zorder(ax2.get_zorder()+1) ax1.patch.set_visible(False) ax2.plot([row[0] for row in dat], [row[8] for row in dat], '-o', color='r',mec='r',markersize=3) ax1.plot([row[0] for row in dat], [row[7] for row in dat], '-^', color='k',markersize=3) for tl in ax2.get_yticklabels(): tl.set_color('r') ax2.set_ylabel('Number of genotypes', color='r') ax2.set_yscale('log') if af_xlog: ax1.set_xscale('log') if af_xlog: ax2.set_xscale('log') ax1.set_ylabel('Aggregate allelic R\$^2\$', color='k') ax1.set_xlabel('Non-ref allele frequency') plt.subplots_adjust(left=0.19,right=0.83,bottom=0.11) plt.savefig('$img2.png') if img_fmt != 'png': plt.savefig('$img2.' + img_fmt) plt.close() "; } sub plot_concordance_by_sample { my ($opts) = @_; my @vals = get_values($opts,2,'GCsS'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "gts_by_sample"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Sample ID\t[2]Discordance\t[3]Sample Name\n"; for (my $i=0; $i<@vals; $i++) { printf $tfh "%d\t%f\t%s\n", $i, $vals[$i][1], $vals[$i][0]; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append(row) if plot_discordance_by_sample: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[1] for row in dat],'.',color='orange') ax1.set_ylabel('Non-ref discordance') ax1.set_ylim(0,) if sample_names: plt.xticks([int(row[0]) for row in dat],[row[2] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_counts_by_AF { my ($opts) = @_; plot_counts_by_AF_col($opts,1,'SNP'); plot_counts_by_AF_col($opts,4,'Indel'); } sub plot_counts_by_AF_col { my ($opts,$col,$title) = @_; my $fh = $$opts{plt_fh}; my $img = "counts_by_af.".lc($title)."s"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]id\t[2]Nonref Allele Frequency\t[3]Number of sites\n"; for my $id (file_ids($opts)) { my @tmp = get_values($opts,$id,'AF'); my $vals = rebin_values(\@tmp,1,0); for my $val (@$vals) { if ( !$$val[$col] ) { next; } print $tfh "$id\t$$val[0]\t$$val[$col]\n"; } } close($tfh); tprint $fh, " dat = {} with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] == '#': continue id = int(row[0]) if id not in dat: dat[id] = [] dat[id].append([float(row[1]),float(row[2])]) if plot_${title}_count_by_af: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.set_ylabel('Number of sites') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') ax1.set_yscale('log') if af_xlog: ax1.set_xscale('log') ax1.set_xlabel('Non-reference allele frequency') ax1.set_xlim(-0.05,1.05) has_data = 0 "; for my $id (file_ids($opts)) { tprint $fh, " if $id in dat and len(dat[$id])>2: ax1.plot([row[0] for row in dat[$id]], [row[1] for row in dat[$id]], '-o',markersize=3, color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]',label='$$opts{title}{$id}') has_data = 1 "; } tprint $fh, " if has_data: ax1.legend(numpoints=1,markerscale=1,loc='best',prop={'size':10},frameon=False) plt.title('$title count by AF') plt.subplots_adjust(bottom=0.2,left=0.1,right=0.95) plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_overlap_by_AF { my ($opts) = @_; plot_overlap_by_AF_col($opts,1,'SNP'); plot_overlap_by_AF_col($opts,4,'Indel'); } sub plot_overlap_by_AF_col { my ($opts,$col,$title) = @_; my @ids = file_ids($opts); if ( @ids != 3 ) { return; } my ($ia,$ib,$iab); for (my $i=0; $i<@ids; $i++) { if ( @{$$opts{dat}{ID}{$ids[$i]}[0]}>1 ) { $iab = $i; next; } if ( !defined $ia ) { $ia = $i; next; } $ib = $i; } my $fh = $$opts{plt_fh}; my $img = "overlap_by_af.".lc($title)."s"; my @has_vals; my @vals_a = get_values($opts,$ia,'AF'); my @vals_b = get_values($opts,$ib,'AF'); my @vals_ab = get_values($opts,$iab,'AF'); my (%afs,%af_a,%af_ab); for my $val (@vals_a) { $afs{$$val[0]} = $$val[$col]; $af_a{$$val[0]} = $$val[$col]; } for my $val (@vals_ab) { $afs{$$val[0]} = $$val[$col]; $af_ab{$$val[0]} = $$val[$col]; } open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Allele frequency\t[2]Fraction of sites from $$opts{title}{$ids[$ia]} also in $$opts{title}{$ids[$ib]}\t[3]Number of sites\n"; for my $af (sort { $a<=>$b } keys %afs) { my $a = exists($af_a{$af}) ? $af_a{$af} : 0; my $ab = exists($af_ab{$af}) ? $af_ab{$af} : 0; my $yval = ($a+$ab) ? $ab * 100. / ($a + $ab) : 0; print $tfh "$af\t$yval\t" .($a+$ab). "\n"; } close($tfh) or error("close $img.dat"); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append(row) if plot_${title}_overlap_by_af and len(dat)>1: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[1] for row in dat],'-o',markersize=3, color='$$opts{id2col}[1]',mec='$$opts{id2col}[1]') ax1.set_ylabel('Fraction found in $$opts{title}{$ib} [%]') ax1.set_xscale('log') ax1.set_xlabel('Non-reference allele frequency in $$opts{title}{$ia}') ax1.set_xlim(0,1.01) plt.title('$title overlap by AF') plt.subplots_adjust(bottom=0.2,left=0.1,right=0.95) plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_indel_distribution { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'IDD'); if ( !@vals ) { return; } # Set xlim to show 99% of indels but ignore outliers my @tmp; for my $id (file_ids($opts)) { my @v = get_values($opts,$id,'IDD'); for my $v (@v) { $tmp[ abs($$v[0]) ] += $$v[1]; } } my $n; for my $t (@tmp) { $n += $t ? $t : 0; } my ($sum,$xlim); for ($xlim=0; $xlim<@tmp; $xlim++) { $sum += $tmp[$xlim] ? $tmp[$xlim] : 0; if ( $sum/$n >= 0.99 ) { last; } } if ( $xlim<20 ) { $xlim=20; } my $fh = $$opts{plt_fh}; my $img = "indels.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Indel length\t[2]Count\n"; for my $val (@vals) { print $tfh "$$val[0]\t$$val[1]\n"; } close($tfh); tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row]) if plot_indel_dist and len(dat)>0: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) ax1.bar([row[0]-0.5 for row in dat], [row[1] for row in dat], color='$$opts{id2col}[0]')# , edgecolor='$$opts{id2col}[0]') ax1.set_xlabel('InDel Length') ax1.set_ylabel('Count') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') ax1.set_xlim(-$xlim,$xlim) plt.subplots_adjust(bottom=0.17) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_indel_vaf_distribution { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'IDD'); if ( !@vals ) { return; } my ($xmin,$xmax); my @dat = (); for my $val (@vals) { if ( $$val[2] eq '0' or $$val[3] eq '.' ) { next; } if ( !defined $xmin or $$val[0]<$xmin ) { $xmin = $$val[0]; } if ( !defined $xmax or $$val[0]>$xmax ) { $xmax = $$val[0]; } push @dat, "$$val[0]\t$$val[3]\n"; } if ( !@dat ) { return; } my $img = "indel_vaf.$id"; open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); print $tfh "# [1]Indel length\t[2]Mean VAF\n"; print $tfh @dat; close($tfh); my $fh = $$opts{plt_fh}; tprint $fh, " dat = [] with open('$img.dat', 'r') as f: reader = csv.reader(f, 'tab') for row in reader: if row[0][0] != '#': dat.append([float(x) for x in row]) if plot_indel_vaf and len(dat)>0: fig = plt.figure(figsize=($$opts{img_width}*2,$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([$xmin,$xmax], [0.5,0.5],color='#c5c5c5') ax1.plot([row[0] for row in dat], [row[1] for row in dat],'.-',color='$$opts{id2col}[0]')# , edgecolor='$$opts{id2col}[0]') ax1.set_xlabel('Size of deletion (negative) or insertion (positive)') ax1.set_ylabel('Fraction of alt allele') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') plt.subplots_adjust(bottom=0.2) plt.title('$$opts{title}{$id}') ax1.spines['top'].set_visible(False) ax1.spines['right'].set_visible(False) ax1.get_xaxis().tick_bottom() ax1.get_yaxis().tick_left() ax1.spines['bottom'].set_color('grey') ax1.spines['left'].set_color('grey') mpl.rcParams['text.color'] = '555555' ax1.patch.set_visible(False) plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_substitutions { my ($opts,$id) = @_; my @vals = get_values($opts,$id,'ST'); if ( !@vals ) { return; } my $fh = $$opts{plt_fh}; my $img = "substitutions.$id"; tprint $fh, " dat = [ "; for (my $i=0; $i<@vals; $i++) { my $val=$vals[$i]; tprint $fh, "\t[$i,'$$val[0]',$$val[1]],\n"; } tprint $fh, "]\n"; tprint $fh, " if plot_substitutions: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ts = [ 'A>G','G>A','C>T','T>C' ] nts = 0 ntv = 0 for x in dat: if x[1] in ts: nts += 1 else: ntv += 1 n = 12 col = list(range(n)) ecol = list(range(n)) for i in range(n): col[i] = '#ffce84' ecol[i] = '#f5c781' col[1] = col[5] = col[6] = col[10] = '#ff9900' ecol[1] = ecol[5] = ecol[6] = ecol[10] = '#ef8f00' ax1 = fig.add_subplot(111) ax1.bar([row[0] for row in dat], [row[2] for row in dat], color=col, edgecolor=ecol) ax1.set_ylabel('Count') ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') ax1.spines['top'].set_visible(False) ax1.spines['right'].set_visible(False) ax1.get_xaxis().tick_bottom() ax1.get_yaxis().tick_left() ax1.spines['bottom'].set_color('grey') ax1.spines['left'].set_color('grey') mpl.rcParams['text.color'] = '555555' ax1.patch.set_visible(False) ax1.set_xlim(-0.5,n-0.5) plt.xticks([row[0] for row in dat],[row[1] for row in dat],rotation=45) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_vaf { my ($opts,$id,$type) = @_; my @vals = get_values($opts,$id,'VAF'); if ( !@vals ) { return; } my @sum = (); for my $row (@vals) { my @cnt = split(/,/,$type eq 'snv' ? $$row[1] : $$row[2]); for (my $i=0; $i<@cnt; $i++) { $sum[$i] += $cnt[$i]; } } my $fh = $$opts{plt_fh}; my $img = "vaf.$type.$id"; tprint $fh, " dat = [ "; for (my $i=0; $i<@sum; $i++) { tprint $fh, "\t[".1.0*$i/(scalar @sum).",$sum[$i]],\n"; } tprint $fh, "]\n"; tprint $fh, " if plot_vaf_$type: fig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) ax1 = fig.add_subplot(111) wd = 0.7 # fraction of dx distance min_dx = None for i in range(len(dat)-1): if min_dx==None or min_dx > abs(dat[i+1][0]-dat[i][0]): min_dx = abs(dat[i+1][0]-dat[i][0]) if min_dx==None: min_dx = 1 wd = min_dx*wd ax1.bar([x[0] for x in dat],[x[1] for x in dat],wd) #,**plt_args) ax1.set_ylabel('Count') ax1.set_xlabel('Variant Allele Frequency') ax1.ticklabel_format(style='sci', scilimits=(-2,2), axis='y') ax1.spines['top'].set_visible(False) ax1.spines['right'].set_visible(False) ax1.get_xaxis().tick_bottom() ax1.get_yaxis().tick_left() ax1.spines['bottom'].set_color('grey') ax1.spines['left'].set_color('grey') mpl.rcParams['text.color'] = '555555' ax1.patch.set_visible(False) plt.subplots_adjust(right=0.95,bottom=0.15) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub plot_vaf25_by_sample { my ($opts,$id,$type) = @_; my @vals = get_values($opts,$id,'VAF'); if ( !@vals ) { return; } my @vaf = (); for my $row (@vals) { my @cnt = split(/,/,$type eq 'snv' ? $$row[1] : $$row[2]); my $sum = 0; my $sum25 = 0; for (my $i=0; $i<@cnt; $i++) { if ( 1.0*$i/(scalar @cnt) < 0.25 ) { $sum25 += $cnt[$i] } $sum += $cnt[$i]; } push @vaf, $sum ? $sum25/$sum : 0; } my $fh = $$opts{plt_fh}; my $img = "vaf25.$type.$id"; tprint $fh, " dat = [ "; for (my $i=0; $i<@vaf; $i++) { tprint $fh, "\t[$i,$vaf[$i]],\n"; } tprint $fh, "]\n"; tprint $fh, " if plot_vaf25_$type: fig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) ax1 = fig.add_subplot(111) ax1.plot([row[0] for row in dat], [row[1] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') ax1.set_ylabel('nVAF<0.25') ax1.set_ylim(-0.1,1.1) if sample_names: plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) plt.subplots_adjust(**sample_margins) else: plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) ax1.set_xlabel('Sample ID') ax1.spines['top'].set_visible(False) ax1.spines['right'].set_visible(False) ax1.get_xaxis().tick_bottom() ax1.get_yaxis().tick_left() ax1.spines['bottom'].set_color('grey') ax1.spines['left'].set_color('grey') mpl.rcParams['text.color'] = '555555' ax1.patch.set_visible(False) plt.title('$$opts{title}{$id}') plt.savefig('$img.png') if img_fmt != 'png': plt.savefig('$img.' + img_fmt) plt.close() "; } sub singletons { my ($opts,$id) = @_; my @si_vals = get_values($opts,$id,'SiS'); my $si_snps = $si_vals[0][1]; my $si_indels = $si_vals[0][4]; my $si_irc = sprintf "%.3f", $si_vals[0][6] ? $si_vals[0][5]/($si_vals[0][5]+$si_vals[0][6]) : 0; my $si_tstv = sprintf "%.2f", $si_vals[0][3] ? $si_vals[0][2]/$si_vals[0][3] : 0; my @all_vals = get_values($opts,$id,'AF'); my $nsnps = 0; my $nindels = 0; for my $val (@all_vals) { $nsnps += $$val[1]; $nindels += $$val[4]; } $si_snps = sprintf "%.1f", $nsnps ? $si_snps*100./$nsnps : 0; $si_indels = sprintf "%.1f", $nindels ? $si_indels*100./$nindels : 0; return { snps=>$si_snps, indels=>$si_indels, tstv=>$si_tstv, irc=>$si_irc }; } sub calc_3n_n3n { my (@vals) = @_; my $n3 = 0; my $nn3 = 0; for my $val (@vals) { if ( !($$val[0]%3) ) { $n3++; } else { $nn3++; } } if ( !$nn3 ) { return '-'; } return sprintf("%.2f", $n3/$nn3); } sub fmt_slide3v { my ($opts, $image, $title) = @_; my $n = 0; for my $id (0..2) { if ( -e "$image.$id.$$opts{img_fmt}" ) { $n++; } } if ( !$n ) { return ''; } my $h = $$opts{tex}{slide3v}{"height$n"}; my $slide = q[\vbox{]; for my $id (0..2) { if ( !-e "$image.$id.$$opts{img_fmt}" ) { next; } $slide .= qq[\\centerline{\\includegraphics[height=$h]{\{$image.$id\}.$$opts{img_fmt}}}]; } $slide .= '}'; return qq[ % $title % \\hslide{$title}{$slide} ]; } sub fmt_slide3h { my ($opts, $image, $title) = @_; my $n = 0; for my $id (0..2) { if ( -e "$image.$id.$$opts{img_fmt}" ) { $n++; } } if ( !$n ) { return ''; } my $w = $$opts{tex}{slide3h}{"width$n"}; my $slide = ''; for my $id (0..2) { if ( !-e "$image.$id.$$opts{img_fmt}" ) { next; } $slide .= qq[\\includegraphics[width=$w]{\{$image.$id\}.$$opts{img_fmt}}]; } return qq[ % $title % \\hslide{$title}{$slide} ]; } sub bignum { my ($num) = @_; if ( !defined $num ) { return ''; } if ( !($num=~/^\d+$/) ) { return $num; } my $len = length($num); my $out; for (my $i=0; $i<$len; $i++) { $out .= substr($num,$i,1); if ( $i+1<$len && !(($len-$i-1)%3) ) { $out .= ','; } } return $out; } sub create_pdf { my ($opts) = @_; chdir($$opts{dir}); my @ids = file_ids($opts); my $width = "25.4cm"; # todo: move all this to $$opts{tex} my $height = "19cm"; my $height1 = "13cm"; my $width1 = "23cm"; my $width2 = @ids==3 ? "10.5cm" : "10.5cm"; my $width3 = @ids==3 ? "8cm" : "15cm"; my $args = { width3=>$width3, n=>scalar @ids }; my $engine = ''; system('command -v pdflatex >/dev/null'); if ($? == 0) { $engine = 'pdflatex'; } else { system('command -v tectonic >/dev/null'); if ($? == 0) { $engine = 'tectonic'; } } if (! $engine) { error('Neither pdflatex or tectonic were found in your PATH, impossible to create a PDF') } # Check that xcolor is available my @has_xcolor = $engine eq 'tectonic' || `kpsewhich xcolor.sty`; if ( !@has_xcolor ) { warn("Note: The xcolor.sty package not available, black and white tables only...\n\n"); } my $tex_file = "summary.tex"; my $pdf_file = "summary.pdf"; open(my $tex,'>',$tex_file) or error("$tex_file: $!"); tprint $tex, qq[ % This file was produced by plot-vcfstats, the command line was: % $$opts{args} % % Edit as necessary and recreate the PDF by running % $engine $tex_file % % Slides style and dimensions % \\nonstopmode \\documentclass[17pt]{memoir} \\setstocksize{$height}{$width} \\settrimmedsize{\\stockheight}{\\stockwidth}{*} \\settrims{0pt}{0pt} \\setlrmarginsandblock{1cm}{*}{*} \\setulmarginsandblock{1.5cm}{*}{*} \\setheadfoot{1mm}{1cm} \\setlength{\\parskip}{0pt} \\setheaderspaces{*}{1mm}{*} \\setmarginnotes{1mm}{1mm}{1mm} \\checkandfixthelayout[fixed] \\usepackage{charter} % font \\pagestyle{plain} \\makeevenfoot{plain}{}{}{\\thepage} \\makeoddfoot{plain}{}{}{\\thepage} \\usepackage{graphicx} % For colored tables. If xcolor.sty is not available on your system, % download xcolor.sty.gz LaTeX class style from % http://www.ukern.de/tex/xcolor.html % Unpack and install system-wide or place elsewhere and make available by % setting the TEXINPUTS environment variable (note the colon) % export TEXINPUTS=some/dir: % The list of the recognised path can be obtained by running `kpsepath tex` % \\usepackage{multirow} \\setlength{\\tabcolsep}{0.6em} \\renewcommand{\\arraystretch}{1.2} ]; if ( @has_xcolor ) { tprint $tex, '\usepackage[table]{xcolor}'; } else { tprint $tex, qq[ \\newcommand{\\definecolor}[3]{} \\newcommand{\\columncolor}[1]{} \\newcommand{\\rowcolors}[4]{} \\newcommand{\\arrayrulecolor}[1]{} ]; } tprint $tex, qq[ \\definecolor{hcol1}{rgb}{1,0.6,0} \\definecolor{hcol2}{rgb}{1,0.68,0.2} \\definecolor{row1}{rgb}{1,0.88,0.7} \\definecolor{row2}{rgb}{1,0.92,0.8} % #FFEBCC \\setlength{\\arrayrulewidth}{1.5pt} % Slide headings \\newcommand*{\\head}[1]{{\\Large\\centerline{#1}\\vskip0.5em}} % Slide definition \\newcommand*{\\hslide}[2]{% \\head{#1}% \\begin{vplace}[0.5]\\centerline{#2}\\end{vplace}\\newpage} \\newcommand{\\pdf}[2]{\\IfFileExists{#2}{\\includegraphics[#1]{#2}}{}} % The actual slides \\begin{document} ]; # Table with summary numbers my $slide .= q[ \begin{minipage}{\textwidth}\centering \small \rowcolors*{3}{row2}{row1} \arrayrulecolor{black} \begin{tabular}{l | r r r | r r | r | r} \multicolumn{1}{>{\columncolor{hcol1}}l|}{} & \multicolumn{3}{>{\columncolor{hcol1}}c|}{SNPs} & \multicolumn{2}{>{\columncolor{hcol1}}c|}{indels} & \multicolumn{1}{>{\columncolor{hcol1}}c|}{MNPs} & \multicolumn{1}{>{\columncolor{hcol1}}c}{others} \\\\ % \multicolumn{1}{>{\columncolor{hcol2}}l|}{Callset} & \multicolumn{1}{>{\columncolor{hcol2}}c}{n} & \multicolumn{1}{>{\columncolor{hcol2}}c }{ts/tv} & \multicolumn{1}{>{\columncolor{hcol2}}c|}{\\footnotesize(1st ALT)} & \multicolumn{1}{>{\columncolor{hcol2}}c}{n} & \multicolumn{1}{>{\columncolor{hcol2}}c}{frm$^*$} & \multicolumn{1}{>{\columncolor{hcol2}}c|}{} & \multicolumn{1}{>{\columncolor{hcol2}}c}{} \\\\ \hline ]; my %tex_titles; for my $id (@ids) { my $snps = get_value($opts,$id,'number of SNPs:'); my $indels = get_value($opts,$id,'number of indels:'); my $mnps = get_value($opts,$id,'number of MNPs:'); my $others = get_value($opts,$id,'number of others:'); my $tstv = sprintf "%.2f",get_values($opts,$id,'TSTV',0,2); my $tstv1 = sprintf "%.2f",get_values($opts,$id,'TSTV',0,5); my @frsh = get_values($opts,$id,'FS'); my $frsh = @frsh ? $frsh[0][3] : '--'; my @rc = get_values($opts,$id,'ICS'); my $title = $$opts{title}{$id}; $title =~ s/_/\\_/g; $title =~ s/^\s*\*/\$*\$/; # leading asterisks is eaten by TeX $tex_titles{$id} = $title; $slide .= qq[ $title & ] . bignum($snps) . qq[ & $tstv & $tstv1 & ] . bignum($indels) . qq[ & $frsh & ] . bignum($mnps) . ' & ' . bignum($others) . qq[ \\\\ \n]; } $slide .= q[% \multicolumn{8}{r}{$^*$ frameshift ratio: out/(out+in)} \\\\ \end{tabular} \\\\ \vspace{1em} \begin{tabular}{l | r r r | r r} \multicolumn{1}{>{\columncolor{hcol1}}l|}{} & \multicolumn{3}{>{\columncolor{hcol1}}c|}{singletons {\footnotesize(AC=1)}} & \multicolumn{2}{>{\columncolor{hcol1}}c}{multiallelic} \\\\ % \multicolumn{1}{>{\columncolor{hcol2}}l|}{Callset} & \multicolumn{1}{>{\columncolor{hcol2}}c}{SNPs} & \multicolumn{1}{>{\columncolor{hcol2}}c}{ts/tv} & \multicolumn{1}{>{\columncolor{hcol2}}c}{indels} & \multicolumn{1}{>{\columncolor{hcol2}}c}{sites} & \multicolumn{1}{>{\columncolor{hcol2}}c}{SNPs} \\\\ \hline ]; for my $id (@ids) { my $snps = get_value($opts,$id,'number of SNPs:'); my $s = singletons($opts,$id); my $mals = get_value($opts,$id,'number of multiallelic sites:'); my $msnps = get_value($opts,$id,'number of multiallelic SNP sites:'); my $title = $tex_titles{$id}; $slide .= qq[ $title & $$s{snps}\\% & $$s{tstv} & $$s{indels}\\% & ] . bignum($mals) . ' &' . bignum($msnps) . qq[ \\\\ \n]; } $slide .= q[ \\end{tabular} \\vspace{2em} \\begin{itemize}[-] \\setlength{\\itemsep}{0pt} ]; for my $id (@ids) { my $fname = $$opts{dat}{ID}{$id}[0][0]; if ( $$opts{title}{$id} =~ / \+ / ) { next; } $fname =~ s/.{80}/$&\\\\\\hskip2em /g; $fname =~ s/_/\\_/g; $slide .= qq[\\item $tex_titles{$id} .. \\texttt{\\footnotesize $fname}\n]; } $slide .= q[\\end{itemize}\\end{minipage}]; my $title = exists($$opts{main_title}) ? $$opts{main_title} : 'Summary Numbers'; tprint $tex, qq[ % Table with summary numbers % \\hslide{$title}{$slide} ]; # Venn bars if ( @ids==3 ) { tprint $tex, qq[% % Venn numbers % \\hslide{Total counts}{% \\includegraphics[width=$width2]{{venn_bars.snps}.$$opts{img_fmt}}% \\includegraphics[width=$width2]{{venn_bars.indels}.$$opts{img_fmt}} } ]; } tprint $tex, fmt_slide3v($opts, "tstv_by_sample", 'Ts/Tv by sample'); tprint $tex, fmt_slide3v($opts, "vaf25.snv", 'Fraction of SNVs with VAF$<$25\% by sample'); tprint $tex, fmt_slide3v($opts, "vaf25.indel", 'Fraction of indels with VAF$<$25\% by sample'); tprint $tex, fmt_slide3v($opts, "hets_by_sample", 'Hets vs non-ref Homs by sample'); tprint $tex, fmt_slide3v($opts, "singletons_by_sample", 'Singletons by sample {\normalsize(hets and homs)}'); tprint $tex, fmt_slide3v($opts, "dp_by_sample", 'Average depth by sample'); tprint $tex, fmt_slide3v($opts, "snps_by_sample", 'Number of SNPs by sample'); tprint $tex, fmt_slide3v($opts, "indels_by_sample", 'Number of indels by sample'); if ( scalar get_values($opts,2,'GCsS') ) { tprint $tex, qq[ % Genotype discordance by sample % \\hslide{Genotype discordance by sample}{\\pdf{width=$width1}{gts_by_sample.$$opts{img_fmt}}} ]; } if ( scalar get_values($opts,2,'GCsAF') ) { my @vals = get_values($opts,2,'NRDs'); my $nrd = sprintf "%.2f", $vals[0][0]; my $rr = sprintf "%.2f", $vals[0][1]; my $ra = sprintf "%.2f", $vals[0][2]; my $aa = sprintf "%.2f", $vals[0][3]; my $nsamples = get_value($opts,2,'number of samples:'); my $table = qq[% {\\small \\rowcolors*{1}{row2}{row1}\\arrayrulecolor{black} \\begin{tabular}{c | c | c | c } \\multicolumn{1}{>{\\columncolor{hcol1}}c|}{REF/REF} & \\multicolumn{1}{>{\\columncolor{hcol1}}c|}{REF/ALT} & \\multicolumn{1}{>{\\columncolor{hcol1}}c|}{ALT/ALT} & \\multicolumn{1}{>{\\columncolor{hcol1}}c}{NRDs} \\\\ \\hline $rr\\% & $ra\\% & $aa\\% & $nrd\\% \\\\ \\end{tabular}}]; tprint $tex, qq[ % Genotype discordance by AF % \\head{Genotype discordance by AF}\\begin{vplace}[0.7]\\centerline{$table}% \\centerline{\\pdf{height=$height1}{gts_by_af.$$opts{img_fmt}}}\\end{vplace} \\newpage % dosage r2 by AF % \\hslide{Allelic R\$^2\$ by AF}{\\pdf{height=$height1}{r2_by_af.$$opts{img_fmt}}} ]; } if ( -e "counts_by_af.snps.$$opts{img_fmt}" && -e "counts_by_af.indels.$$opts{img_fmt}" ) { tprint $tex, qq[ % SNP and indel counts by AF % \\hslide{}{\\vbox{\\noindent\\includegraphics[width=$width1]{{counts_by_af.snps}.$$opts{img_fmt}}\\\\% \\noindent\\includegraphics[width=$width1]{{counts_by_af.indels}.$$opts{img_fmt}}}} ]; } if ( -e "overlap_by_af.snps.$$opts{img_fmt}" && -e "overlap_by_af.indels.$$opts{img_fmt}" ) { tprint $tex, qq[ % SNP and indel overlap by AF % \\hslide{}{\\vbox{\\noindent\\includegraphics[width=$width1]{{overlap_by_af.snps}.$$opts{img_fmt}}\\\\% \\noindent\\includegraphics[width=$width1]{{overlap_by_af.indels}.$$opts{img_fmt}}}} ]; } tprint $tex, fmt_slide3h($opts, "tstv_by_af", 'Ts/Tv by AF'); tprint $tex, fmt_slide3h($opts, "tstv_by_qual", 'Ts/Tv stratified by QUAL'); for my $plot (@{$$opts{usr_plots}}) { my $uname = $$plot{uname}; my $fname = $$plot{fname}; tprint $tex, fmt_slide3h($opts, $fname, 'Ts/Tv stratified by '.$uname); } tprint $tex, fmt_slide3h($opts, "indels", 'Indel distribution'); tprint $tex, fmt_slide3v($opts, "indel_vaf", 'Fraction of alternate indel allele'); tprint $tex, fmt_slide3h($opts, "depth", 'Depth distribution'); tprint $tex, fmt_slide3h($opts, "hwe", 'Number of HETs by AF'); tprint $tex, fmt_slide3h($opts, "substitutions", 'Substitution types'); tprint $tex, fmt_slide3h($opts, "vaf.snv", 'SNV Variant Allele Frequency'); tprint $tex, fmt_slide3h($opts, "vaf.indel", 'Indel Variant Allele Frequency'); #tprint $tex, fmt_slide3h($opts, "irc_by_af", 'Indel Repeat Consistency by AF'); #tprint $tex, fmt_slide3h($opts, "irc_by_rlen", 'Indel Consistency by Repeat Type'); tprint $tex, "\n\n\\end{document}\n"; close($tex); $tex_file =~ s{^.+/}{}; my $cmd = "$engine $tex_file >$$opts{logfile} 2>&1"; print STDERR "Creating PDF: $cmd\n" unless !$$opts{verbose}; system($cmd); if ( $? ) { error("The command exited with non-zero status, please consult the output of $engine: $$opts{dir}/$$opts{logfile}\n\n"); } print STDERR "Finished: $$opts{dir}/$pdf_file\n" unless !$$opts{verbose}; } sub merge_vcfstats { my ($opts) = @_; my $fh = *STDOUT; if ( !$$opts{merge} ) { open($fh,'>',"merge.chk") or error("merge.chk: $!\n"); } print $fh "# This file was produced by plot-vcfstats, the command line was:\n# $$opts{args}\n#\n"; for my $sec (@{$$opts{sections}}) { my $sid = $$sec{id}; if ( !exists($$opts{dat}{$sid}) ) { next; } print $fh "# $$sec{header}\n$$sec{exp}\n"; for my $id (sort keys %{$$opts{dat}{$sid}}) { for my $rec (@{$$opts{dat}{$sid}{$id}}) { print $fh "$sid\t$id\t", join("\t",@$rec), "\n"; } } if ( $sid eq 'ID' ) { print $fh "# $$opts{id2sec}{SN}{header}\n$$opts{id2sec}{SN}{exp}\n"; # output summary numbers here for my $id (keys %{$$opts{dat}}) { if ( exists($$opts{exp}{$id}) ) { next; } for my $key (@{$$opts{SN_keys}}) { next unless exists $$opts{dat}{$id}{$key}; print $fh "SN\t$id\t$key\t$$opts{dat}{$id}{$key}\n"; } } } } } bcftools-1.21/misc/run-roh.pl000077500000000000000000000331641467060157400161560ustar00rootroot00000000000000#!/usr/bin/env perl # # The MIT License # # Copyright (c) 2017-2022 Genome Research Ltd. # # Author: Petr Danecek # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE # AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, # OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN # THE SOFTWARE. use strict; use warnings; use Carp; use Data::Dumper; my $opts = parse_params(); run_roh($opts); eval_roh($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg,"\n"; } print "About: This is a convenience wrapper for \"bcftools roh\" which takes multiple VCF/BCF files\n", " and locates regions private to a sample or shared across multiple samples. On input it\n", " expects a directory with .vcf, .vcf.gz or .bcf files, a file with allele frequencies\n", " and optionally a genetic map. See http://samtools.github.io/bcftools/howtos/roh-calling.html\n", " for details\n", "Usage: run-roh.pl [OPTIONS]\n", "Options:\n", " -a, --af-annots Allele frequency annotations (optional)\n", " -i, --indir Input directory with VCF files\n", " --include Select sites for which the expression is true\n", " --exclude Exclude sites for which the epxression is true\n", " -l, --min-length Filter input regions shorter than this [1e6]\n", " -m, --genmap Directory with genetic map in IMPUTE2 format (optional)\n", " -M, --rec-rate constant recombination rate per bp (optional)\n", " -n, --min-markers Filter input regions with fewer marker than this [100]\n", " -o, --outdir Output directory\n", " -q, --min-qual Filter input regions with quality smaller than this [10]\n", " --roh-args Extra arguments to pass to bcftools roh\n", " -s, --silent Quiet output, do not print commands\n", " -h, -?, --help This help message\n", "\n"; exit -1; } sub parse_params { my $opts = { verbose => 1, min_length => 1e6, min_markers => 100, min_qual => 10, roh_args => '', }; while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '--roh-args' ) { $$opts{roh_args}=shift(@ARGV); next } if ( $arg eq '--include' ) { $$opts{include_expr}=shift(@ARGV); next } if ( $arg eq '--exclude' ) { $$opts{exclude_expr}=shift(@ARGV); next } if ( $arg eq '-q' || $arg eq '--min-qual' ) { $$opts{min_qual}=shift(@ARGV); next } if ( $arg eq '-l' || $arg eq '--min-length' ) { $$opts{min_length}=shift(@ARGV); next } if ( $arg eq '-n' || $arg eq '--min-markers' ) { $$opts{min_markers}=shift(@ARGV); next } if ( $arg eq '-s' || $arg eq '--silent' ) { $$opts{verbose}=0; next } if ( $arg eq '-a' || $arg eq '--af-annots' ) { $$opts{af_annots}=shift(@ARGV); next } if ( $arg eq '-m' || $arg eq '--genmap' ) { $$opts{genmap}=shift(@ARGV); next } if ( $arg eq '-M' || $arg eq '--rec-rate' ) { $$opts{rec_rate}=shift(@ARGV); next } if ( $arg eq '-o' || $arg eq '--outdir' ) { $$opts{outdir}=shift(@ARGV); next } if ( $arg eq '-i' || $arg eq '--indir' ) { $$opts{indir}=shift(@ARGV); next } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } if ( !exists($$opts{outdir}) ) { error("Missing the -o, --outdir option.\n") } if ( !exists($$opts{indir}) ) { error("Missing the -i, --indir option.\n") } if ( exists($$opts{af_annots}) ) { if ( ! -e $$opts{af_annots} ) { error("The annotation file does not exist: $$opts{af_annots}\n"); } if ( ! -e "$$opts{af_annots}.tbi" ) { error("The annotation file is not indexed: $$opts{af_annots}.tbi\n"); } if ( ! -e "$$opts{af_annots}.hdr" ) { error("The annotation file has no header: $$opts{af_annots}.hdr\n"); } } if ( exists($$opts{genmap}) && ! -d "$$opts{genmap}" ) { error("The directory with genetic maps does not exist: $$opts{genmap}\n"); } if ( exists($$opts{include_expr}) ) { $$opts{include_expr} =~ s/\'/\'\\\'\'/g; $$opts{inc_exc} .= qq[ -i '$$opts{include_expr}']; } if ( exists($$opts{exclude_expr}) ) { $$opts{exclude_expr} =~ s/\'/\'\\\'\'/g; $$opts{inc_exc} .= qq[ -e '$$opts{exclude_expr}']; } return $opts; } sub cmd { my ($cmd,%args) = @_; if ( $args{verbose} ) { print STDERR $cmd,"\n"; } # Why not to use backticks? Perl calls /bin/sh, which is often bash. To get the correct # status of failing pipes, it must be called with the pipefail option. my $kid_io; my $pid = open($kid_io, "-|"); if ( !defined $pid ) { error("Cannot fork: $!"); } my @out; if ($pid) { # parent @out = <$kid_io>; close($kid_io); } else { # child exec('bash', '-o','pipefail','-c', $cmd) or error("Failed to run the command [bash -o pipefail -c $cmd]: $!"); } if ( exists($args{exit_on_error}) && !$args{exit_on_error} ) { return @out; } my $exit_status = $?; my $status = exists($args{require_status}) ? $args{require_status} : 0; if ( $status ne $exit_status ) { my $msg; if ( $? & 0xff ) { $msg = "The command died with signal ".($? & 0xff); } else { $msg = "The command exited with status ".($? >> 8)." (expected $status)"; } $msg .= ":\n\t$cmd\n\n"; if ( @out ) { $msg .= join('',@out,"\n\n"); } error($msg); } return @out; } # determine the common prefix/suffix in file names like: # genetic_map_chr12_combined_b37.txt # genetic_map_chr13_combined_b37.txt sub parse_genmap_path { my ($opts) = @_; if ( !exists($$opts{genmap}) or !-d $$opts{genmap} ) { return ''; } my @files = glob("$$opts{genmap}/*"); my $prefix = $files[0]; my $suffix = $files[0]; for my $file (@files) { while ( length($prefix) && index($file,$prefix)==-1 ) { substr($prefix,length($prefix)-1,1,''); } if ( !length($prefix) ) { last; } } for my $file (@files) { while ( length($suffix) && rindex($file,$suffix)==-1 ) { substr($suffix,0,1,''); } if ( !length($suffix) ) { last; } } my @test = glob("$prefix*$suffix"); if ( @test != @files ) { error( "Error: Could not determine the genetic map files in \"$$opts{genmap}\". The directory must contain only\n" . " the genetic map files (and nothing else) and the expected file names are\n" . " \n" . " for example:\n" . " genetic_map_chr10_combined_b37.txt\n" . " genetic_map_chr11_combined_b37.txt\n" . " ...\n" . " The heuristically determined wildcard \"$prefix*$suffix\" matches ",scalar @test," files, in total there are ",scalar @files," files.\n"); } return "-m $prefix\{CHROM}$suffix"; } sub run_roh { my ($opts) = @_; cmd("mkdir -p $$opts{outdir}",%$opts) unless -d $$opts{outdir}; my $chr_fname = "$$opts{outdir}/chr-names.txt"; open(my $fh,'>',$chr_fname) or error("$chr_fname: $!"); for my $chr (1..22,'X') { print $fh "chr$chr\t$chr\n"; } close($fh) or error("close failed: $chr_fname"); my @files = (); opendir(my $dh,$$opts{indir}) or error("$$opts{indir}: $!"); while (my $file = readdir($dh)) { if ( !($file=~/\.vcf$/i) && !($file=~/\.vcf\.gz$/i) && !($file=~/\.bcf$/i) ) { next; } my $outfile = "$$opts{outdir}/$`.bcf"; push @files,$outfile; if ( -e $outfile ) { next; } my $cmd = "bcftools annotate --rename-chrs $chr_fname '$$opts{indir}/$file'"; if ( exists($$opts{af_annots}) ) { $cmd .= " -Ou | bcftools annotate -c CHROM,POS,REF,ALT,AF1KG -h $$opts{af_annots}.hdr -a $$opts{af_annots} "; } if ( exists($$opts{inc_exc}) ) { $cmd .= " -Ou | bcftools view $$opts{inc_exc} "; } $cmd .= " -Ob -o $outfile.part && "; $cmd .= " mv $outfile.part $outfile"; cmd($cmd, %$opts); } closedir($dh) or error("close failed: $$opts{indir}"); my $genmap = parse_genmap_path($opts); if ( exists($$opts{rec_rate}) ) { $genmap .= " -M $$opts{rec_rate}"; } for my $file (@files) { if ( -e "$file.txt.gz" ) { next; } my @out = cmd("bcftools roh $$opts{roh_args} --AF-tag AF1KG $genmap $file -Orz -o $file.txt.gz.part 2>&1 | tee -a $file.log",%$opts); for my $line (@out) { if ( !($line=~m{total/processed:\s+(\d+)/(\d+)}) ) { next; } my $total = $1; my $used = $2; if ( !$total or $used/$total < 0.3 ) { print STDERR @out; print STDERR "WARNING: Less than 30% of sites was used!\n\n"; } } cmd(qq[bcftools query -f'GT\\t%CHROM\\t%POS[\\t%SAMPLE\\t%GT]\\n' $file | gzip -c >> $file.txt.gz.part && mv $file.txt.gz.part $file.txt.gz],%$opts); } $$opts{files} = \@files; } sub next_region { my ($regions) = @_; my $chr = undef; for my $chrom (sort keys %$regions) { if ( %{$$regions{$chrom}} ) { $chr = $chrom; last; } delete($$regions{$chrom}); } if ( !defined $chr ) { return undef; } my %min = (); for my $smpl (keys %{$$regions{$chr}}) { if ( !exists($$regions{$chr}{$smpl}) ) { next; } my $reg = $$regions{$chr}{$smpl}[0]; if ( !%min ) { $min{chr} = $chr; $min{beg} = $$reg{beg}; $min{end} = $$reg{end}; next; } if ( $min{beg} > $$reg{beg} ) { $min{beg} = $$reg{beg}; } } if ( !%min ) { return undef; } for my $smpl (keys %{$$regions{$chr}}) { if ( !exists($$regions{$chr}{$smpl}) ) { next; } my $reg = $$regions{$chr}{$smpl}[0]; if ( $min{end} > $$reg{end} ) { $min{end} = $$reg{end}; } if ( $min{end} > $$reg{beg} - 1 && $min{beg} != $$reg{beg} ) { $min{end} = $$reg{beg} - 1; } } return \%min; } sub eval_roh { my ($opts) = @_; my %regions = (); my %samples = (); my %lengths = (); for my $file (@{$$opts{files}}) { open(my $fh,"gunzip -c $file.txt.gz |") or error("gunzip -c $file.txt.gz: $!"); while (my $line=<$fh>) { if ( !($line=~/^RG/) ) { next; } my (%vals); @vals{qw(type smpl chr beg end len num qual)} = split(/\s+/,$line); if ( $vals{type} ne 'RG' ) { next; } chomp($vals{qual}); if ( $vals{len} < $$opts{min_length} ) { next; } if ( $vals{num} < $$opts{min_markers} ) { next; } if ( $vals{qual} < $$opts{min_qual} ) { next; } push @{$regions{$vals{chr}}{$vals{smpl}}},\%vals; $samples{$vals{smpl}} = 1; $lengths{$vals{smpl}} += $vals{end} - $vals{beg} + 1; } close($fh) or error("close failed: gunzip -c $file.txt.gz"); } open(my $fh,'>',"$$opts{outdir}/merged.txt") or error("$$opts{outdir}/merged.txt: $!"); my @samples = sort keys %samples; print $fh "# [1]chrom\t[2]beg\t[3]end\t[4]length (Mb)"; my $i = 5; for my $smpl (@samples) { print $fh "\t[$i]$smpl"; $i++; } print $fh "\n"; while (my $min = next_region(\%regions)) { my $chr = $$min{chr}; my $beg = $$min{beg}; my $end = $$min{end}; printf $fh "$chr\t$beg\t$end\t%.2f",($end-$beg+1)/1e6; for my $smpl (@samples) { if ( !exists($regions{$chr}{$smpl}) ) { goto not_present; } my $reg = $regions{$chr}{$smpl}[0]; if ( $$reg{beg} > $end ) { goto not_present; } if ( $$reg{end} > $end ) { $regions{$chr}{$smpl}[0]{beg} = $end + 1; } else { shift @{$regions{$chr}{$smpl}}; } if ( !@{$regions{$chr}{$smpl}} ) { delete($regions{$chr}{$smpl}); } $lengths{$smpl} -= $end - $beg + 1; print $fh "\t1"; next; not_present: print $fh "\t0"; } print $fh "\n"; } close($fh) or error("close failed: $$opts{outdir}/merged.txt"); for my $smpl (@samples) { if ( $lengths{$smpl}!=0 ) { print STDERR "ERROR: a bug detected, sanity check failed, expected zero length : $smpl .. $lengths{$smpl}\n"; } } print STDERR "The merged regions are in $$opts{outdir}/merged.txt\n"; } bcftools-1.21/misc/vcfutils.pl000077500000000000000000000434361467060157400164260ustar00rootroot00000000000000#!/usr/bin/env perl # # Copyright (C) 2010 Broad Institute. # Copyright (C) 2011, 2014, 2017 Genome Research Ltd. # # Author: Heng Li # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. use strict; use warnings; use Getopt::Std; &main; exit; sub main { &usage if (@ARGV < 1); my $command = shift(@ARGV); my %func = (subsam=>\&subsam, listsam=>\&listsam, fillac=>\&fillac, qstats=>\&qstats, varFilter=>\&varFilter, hapmap2vcf=>\&hapmap2vcf, ucscsnp2vcf=>\&ucscsnp2vcf, filter4vcf=>\&varFilter, ldstats=>\&ldstats, gapstats=>\&gapstats, splitchr=>\&splitchr, vcf2fq=>\&vcf2fq); die("Unknown command \"$command\".\n") if (!defined($func{$command})); &{$func{$command}}; } sub splitchr { my %opts = (l=>5000000); getopts('l:', \%opts); my $l = $opts{l}; die(qq/Usage: vcfutils.pl splitchr [-l $opts{l}] \n/) if (@ARGV == 0 && -t STDIN); while (<>) { my @t = split; my $last = 0; for (my $i = 0; $i < $t[1];) { my $e = ($t[1] - $i) / $l < 1.1? $t[1] : $i + $l; print "$t[0]:".($i+1)."-$e\n"; $i = $e; } } } sub subsam { die(qq/Usage: vcfutils.pl subsam [samples]\n/) if (@ARGV == 0); my ($fh, %h); my $fn = shift(@ARGV); my @col; open($fh, ($fn =~ /\.gz$/)? "gzip -dc $fn |" : $fn) || die; $h{$_} = 1 for (@ARGV); while (<$fh>) { if (/^##/) { print; } elsif (/^#/) { my @t = split; my @s = @t[0..8]; # all fixed fields + FORMAT for (9 .. $#t) { if ($h{$t[$_]}) { push(@s, $t[$_]); push(@col, $_); } } pop(@s) if (@s == 9); # no sample selected; remove the FORMAT field print join("\t", @s), "\n"; } else { my @t = split; if (@col == 0) { print join("\t", @t[0..7]), "\n"; } else { print join("\t", @t[0..8], map {$t[$_]} @col), "\n"; } } } close($fh); } sub listsam { die(qq/Usage: vcfutils.pl listsam \n/) if (@ARGV == 0 && -t STDIN); while (<>) { if (/^#/ && !/^##/) { my @t = split; print join("\n", @t[9..$#t]), "\n"; exit; } } } sub fillac { die(qq/Usage: vcfutils.pl fillac \n\nNote: The GT field MUST BE present and always appear as the first field.\n/) if (@ARGV == 0 && -t STDIN); while (<>) { if (/^#/) { print; } else { my @t = split; my @c = (0, 0); my $n = 0; my $s = -1; @_ = split(":", $t[8]); for (0 .. $#_) { if ($_[$_] eq 'GT') { $s = $_; last; } } if ($s < 0) { print join("\t", @t), "\n"; next; } for (9 .. $#t) { if ($t[$_] =~ /^0,0,0/) { } elsif ($t[$_] =~ /^([^\s:]+:){$s}(\d+).(\d+)/) { ++$c[$2]; ++$c[$3]; $n += 2; } } my $AC = "AC=" . join("\t", @c[1..$#c]) . ";AN=$n"; my $info = $t[7]; $info =~ s/(;?)AC=(\d+)//; $info =~ s/(;?)AN=(\d+)//; if ($info eq '.') { $info = $AC; } else { $info .= ";$AC"; } $t[7] = $info; print join("\t", @t), "\n"; } } } sub ldstats { my %opts = (t=>0.9); getopts('t:', \%opts); die("Usage: vcfutils.pl ldstats [-t $opts{t}] \n") if (@ARGV == 0 && -t STDIN); my $cutoff = $opts{t}; my ($last, $lastchr) = (0x7fffffff, ''); my ($x, $y, $n) = (0, 0, 0); while (<>) { if (/^([^#\s]+)\s(\d+)/) { my ($chr, $pos) = ($1, $2); if (/NEIR=([\d\.]+)/) { ++$n; ++$y, $x += $pos - $last if ($lastchr eq $chr && $pos > $last && $1 > $cutoff); } $last = $pos; $lastchr = $chr; } } print "Number of SNP intervals in strong LD (r > $opts{t}): $y\n"; print "Fraction: ", $y/$n, "\n"; print "Length: $x\n"; } sub qstats { my %opts = (r=>'', s=>0.02, v=>undef); getopts('r:s:v', \%opts); die("Usage: vcfutils.pl qstats [-r ref.vcf] \n Note: This command discards indels. Output: QUAL #non-indel #SNPs #transitions #joint ts/tv #joint/#ref #joint/#non-indel \n") if (@ARGV == 0 && -t STDIN); my %ts = (AG=>1, GA=>1, CT=>1, TC=>1); my %h = (); my $is_vcf = defined($opts{v})? 1 : 0; if ($opts{r}) { # read the reference positions my $fh; open($fh, $opts{r}) || die; while (<$fh>) { next if (/^#/); if ($is_vcf) { my @t = split; $h{$t[0],$t[1]} = $t[4]; } else { $h{$1,$2} = 1 if (/^(\S+)\s+(\d+)/); } } close($fh); } my $hsize = scalar(keys %h); my @a; while (<>) { next if (/^#/); my @t = split; next if (length($t[3]) != 1 || uc($t[3]) eq 'N'); $t[3] = uc($t[3]); $t[4] = uc($t[4]); my @s = split(',', $t[4]); $t[5] = 3 if ($t[5] eq '.' || $t[5] < 0); next if (length($s[0]) != 1); my $hit; if ($is_vcf) { $hit = 0; my $aa = $h{$t[0],$t[1]}; if (defined($aa)) { my @aaa = split(",", $aa); for (@aaa) { $hit = 1 if ($_ eq $s[0]); } } } else { $hit = defined($h{$t[0],$t[1]})? 1 : 0; } push(@a, [$t[5], ($t[4] eq '.' || $t[4] eq $t[3])? 0 : 1, $ts{$t[3].$s[0]}? 1 : 0, $hit]); } push(@a, [-1, 0, 0, 0]); # end marker die("[qstats] No SNP data!\n") if (@a == 0); @a = sort {$b->[0]<=>$a->[0]} @a; my $next = $opts{s}; my $last = $a[0]; my @c = (0, 0, 0, 0); my @lc; $lc[1] = $lc[2] = 0; for my $p (@a) { if ($p->[0] == -1 || ($p->[0] != $last && $c[0]/@a > $next)) { my @x; $x[0] = sprintf("%.4f", $c[1]-$c[2]? $c[2] / ($c[1] - $c[2]) : 100); $x[1] = sprintf("%.4f", $hsize? $c[3] / $hsize : 0); $x[2] = sprintf("%.4f", $c[3] / $c[1]); my $a = $c[1] - $lc[1]; my $b = $c[2] - $lc[2]; $x[3] = sprintf("%.4f", $a-$b? $b / ($a-$b) : 100); print join("\t", $last, @c, @x), "\n"; $next = $c[0]/@a + $opts{s}; $lc[1] = $c[1]; $lc[2] = $c[2]; } ++$c[0]; $c[1] += $p->[1]; $c[2] += $p->[2]; $c[3] += $p->[3]; $last = $p->[0]; } } sub varFilter { my %opts = (d=>2, D=>10000000, a=>2, W=>10, Q=>10, w=>3, p=>undef, 1=>1e-4, 2=>1e-100, 3=>0, 4=>1e-4, G=>0, S=>1000, e=>1e-4); getopts('pd:D:W:Q:w:a:1:2:3:4:G:S:e:', \%opts); die(qq/ Usage: vcfutils.pl varFilter [options] Options: -Q INT minimum RMS mapping quality for SNPs [$opts{Q}] -d INT minimum read depth [$opts{d}] -D INT maximum read depth [$opts{D}] -a INT minimum number of alternate bases [$opts{a}] -w INT SNP within INT bp around a gap to be filtered [$opts{w}] -W INT window size for filtering adjacent gaps [$opts{W}] -1 FLOAT min P-value for strand bias (given PV4) [$opts{1}] -2 FLOAT min P-value for baseQ bias [$opts{2}] -3 FLOAT min P-value for mapQ bias [$opts{3}] -4 FLOAT min P-value for end distance bias [$opts{4}] -e FLOAT min P-value for HWE (plus F<0) [$opts{e}] -p print filtered variants Note: Some of the filters rely on annotations generated by SAMtools\/BCFtools. \n/) if (@ARGV == 0 && -t STDIN); # calculate the window size my ($ol, $ow) = ($opts{W}, $opts{w}); my $max_dist = $ol > $ow? $ol : $ow; # the core loop my @staging; # (indel_filtering_score, flt_tag, indel_span; chr, pos, ...) while (<>) { my @t = split; if (/^#/) { print; next; } next if ($t[4] eq '.'); # skip non-var sites next if ($t[3] eq 'N'); # skip sites with unknown ref ('N') # check if the site is a SNP my $type = 1; # SNP if (length($t[3]) > 1) { $type = 2; # MNP my @s = split(',', $t[4]); for (@s) { $type = 3 if (length != length($t[3])); } } else { my @s = split(',', $t[4]); for (@s) { $type = 3 if (length > 1); } } # clear the out-of-range elements while (@staging) { # Still on the same chromosome and the first element's window still affects this position? last if ($staging[0][3] eq $t[0] && $staging[0][4] + $staging[0][2] + $max_dist >= $t[1]); varFilter_aux(shift(@staging), $opts{p}); # calling a function is a bit slower, not much } my $flt = 0; # parse annotations my ($dp, $mq, $dp_alt) = (-1, -1, -1); if ($t[7] =~ /DP4=(\d+),(\d+),(\d+),(\d+)/i) { $dp = $1 + $2 + $3 + $4; $dp_alt = $3 + $4; } if ($t[7] =~ /DP=(\d+)/i) { $dp = $1; } $mq = $1 if ($t[7] =~ /MQ=(\d+)/i); # the depth and mapQ filter if ($dp >= 0) { if ($dp < $opts{d}) { $flt = 2; } elsif ($dp > $opts{D}) { $flt = 3; } } $flt = 4 if ($dp_alt >= 0 && $dp_alt < $opts{a}); $flt = 1 if ($flt == 0 && $mq >= 0 && $mq < $opts{Q}); $flt = 7 if ($flt == 0 && /PV4=([^,]+),([^,]+),([^,]+),([^,;\t]+)/ && ($1<$opts{1} || $2<$opts{2} || $3<$opts{3} || $4<$opts{4})); $flt = 8 if ($flt == 0 && ((/MXGQ=(\d+)/ && $1 < $opts{G}) || (/MXSP=(\d+)/ && $1 >= $opts{S}))); # HWE filter if ($t[7] =~ /G3=([^;,]+),([^;,]+),([^;,]+).*HWE=([^;,]+)/ && $4 < $opts{e}) { my $p = 2*$1 + $2; my $f = ($p > 0 && $p < 1)? 1 - $2 / ($p * (1-$p)) : 0; $flt = 9 if ($f < 0); } my $score = $t[5] * 100 + $dp_alt; my $rlen = length($t[3]) - 1; # $indel_score<0 for SNPs if ($flt == 0) { if ($type == 3) { # an indel # filtering SNPs and MNPs for my $x (@staging) { next if (($x->[0]&3) == 3 || $x->[1] || $x->[4] + $x->[2] + $ow < $t[1]); $x->[1] = 5; } # check the staging list for indel filtering for my $x (@staging) { next if (($x->[0]&3) != 3 || $x->[1] || $x->[4] + $x->[2] + $ol < $t[1]); if ($x->[0]>>2 < $score) { $x->[1] = 6; } else { $flt = 6; last; } } } else { # SNP or MNP for my $x (@staging) { next if (($x->[0]&3) != 3 || $x->[4] + $x->[2] + $ow < $t[1]); if ($x->[4] + length($x->[7]) - 1 == $t[1] && substr($x->[7], -1, 1) eq substr($t[4], 0, 1) && length($x->[7]) - length($x->[6]) == 1) { $x->[1] = 5; } else { $flt = 5; } last; } # check MNP for my $x (@staging) { next if (($x->[0]&3) == 3 || $x->[4] + $x->[2] < $t[1]); if ($x->[0]>>2 < $score) { $x->[1] = 8; } else { $flt = 8; last; } } } } push(@staging, [$score<<2|$type, $flt, $rlen, @t]); } # output the last few elements in the staging list while (@staging) { varFilter_aux(shift @staging, $opts{p}); } } sub varFilter_aux { my ($first, $is_print) = @_; if ($first->[1] == 0) { print join("\t", @$first[3 .. @$first-1]), "\n"; } elsif ($is_print) { print STDERR join("\t", substr("UQdDaGgPMS", $first->[1], 1), @$first[3 .. @$first-1]), "\n"; } } sub gapstats { my (@c0, @c1); $c0[$_] = $c1[$_] = 0 for (0 .. 10000); while (<>) { next if (/^#/); my @t = split; next if (length($t[3]) == 1 && $t[4] =~ /^[A-Za-z](,[A-Za-z])*$/); # not an indel my @s = split(',', $t[4]); for my $x (@s) { my $l = length($x) - length($t[3]) + 5000; if ($x =~ /^-/) { $l = -(length($x) - 1) + 5000; } elsif ($x =~ /^\+/) { $l = length($x) - 1 + 5000; } $c0[$l] += 1 / @s; } } for (my $i = 0; $i < 10000; ++$i) { next if ($c0[$i] == 0); $c1[0] += $c0[$i]; $c1[1] += $c0[$i] if (($i-5000)%3 == 0); printf("C\t%d\t%.2f\n", ($i-5000), $c0[$i]); } printf("3\t%d\t%d\t%.3f\n", $c1[0], $c1[1], $c1[1]/$c1[0]); } sub ucscsnp2vcf { die("Usage: vcfutils.pl \n") if (@ARGV == 0 && -t STDIN); print "##fileformat=VCFv4.0\n"; print join("\t", "#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO"), "\n"; while (<>) { my @t = split("\t"); my $indel = ($t[9] =~ /^[ACGT](\/[ACGT])+$/)? 0 : 1; my $pos = $t[2] + 1; my @alt; push(@alt, $t[7]); if ($t[6] eq '-') { $t[9] = reverse($t[9]); $t[9] =~ tr/ACGTRYMKWSNacgtrymkwsn/TGCAYRKMWSNtgcayrkmwsn/; } my @a = split("/", $t[9]); for (@a) { push(@alt, $_) if ($_ ne $alt[0]); } if ($indel) { --$pos; for (0 .. $#alt) { $alt[$_] =~ tr/-//d; $alt[$_] = "N$alt[$_]"; } } my $ref = shift(@alt); my $af = $t[13] > 0? ";AF=$t[13]" : ''; my $valid = ($t[12] eq 'unknown')? '' : ";valid=$t[12]"; my $info = "molType=$t[10];class=$t[11]$valid$af"; print join("\t", $t[1], $pos, $t[4], $ref, join(",", @alt), 0, '.', $info), "\n"; } } sub hapmap2vcf { die("Usage: vcfutils.pl \n") if (@ARGV == 0); my $fn = shift(@ARGV); # parse UCSC SNP warn("Parsing UCSC SNPs...\n"); my ($fh, %map); open($fh, ($fn =~ /\.gz$/)? "gzip -dc $fn |" : $fn) || die; while (<$fh>) { my @t = split; next if ($t[3] - $t[2] != 1); # not SNP @{$map{$t[4]}} = @t[1,3,7]; } close($fh); # write VCF warn("Writing VCF...\n"); print "##fileformat=VCFv4.0\n"; while (<>) { my @t = split; if ($t[0] eq 'rs#') { # the first line print join("\t", "#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO\tFORMAT", @t[11..$#t]), "\n"; } else { next unless ($map{$t[0]}); next if (length($t[1]) != 3); # skip non-SNPs my $a = \@{$map{$t[0]}}; my $ref = $a->[2]; my @u = split('/', $t[1]); if ($u[1] eq $ref) { $u[1] = $u[0]; $u[0] = $ref; } elsif ($u[0] ne $ref) { next; } my $alt = $u[1]; my %w; $w{$u[0]} = 0; $w{$u[1]} = 1; my @s = (@$a[0,1], $t[0], $ref, $alt, 0, '.', '.', 'GT'); my $is_tri = 0; for (@t[11..$#t]) { if ($_ eq 'NN') { push(@s, './.'); } else { my @a = ($w{substr($_,0,1)}, $w{substr($_,1,1)}); if (!defined($a[0]) || !defined($a[1])) { $is_tri = 1; last; } push(@s, "$a[0]/$a[1]"); } } next if ($is_tri); print join("\t", @s), "\n"; } } } sub vcf2fq { my %opts = (d=>3, D=>100000, Q=>10, l=>5); getopts('d:D:Q:l:', \%opts); die(qq/ Usage: vcfutils.pl vcf2fq [options] Options: -d INT minimum depth [$opts{d}] -D INT maximum depth [$opts{D}] -Q INT min RMS mapQ [$opts{Q}] -l INT INDEL filtering window [$opts{l}] \n/) if (@ARGV == 0 && -t STDIN); my ($last_chr, $seq, $qual, $last_pos, @gaps); my $_Q = $opts{Q}; my $_d = $opts{d}; my $_D = $opts{D}; my %het = (AC=>'M', AG=>'R', AT=>'W', CA=>'M', CG=>'S', CT=>'Y', GA=>'R', GC=>'S', GT=>'K', TA=>'W', TC=>'Y', TG=>'K'); $last_chr = ''; while (<>) { next if (/^#/); my @t = split; if ($last_chr ne $t[0]) { &v2q_post_process($last_chr, \$seq, \$qual, \@gaps, $opts{l}) if ($last_chr); ($last_chr, $last_pos) = ($t[0], 0); $seq = $qual = ''; @gaps = (); } die("[vcf2fq] unsorted input\n") if ($t[1] - $last_pos < 0); if ($t[1] - $last_pos > 1) { $seq .= 'n' x ($t[1] - $last_pos - 1); $qual .= '!' x ($t[1] - $last_pos - 1); } if (length($t[3]) == 1 && $t[7] !~ /INDEL/ && $t[4] =~ /^([A-Za-z.])(,[A-Za-z])*$/) { # a SNP or reference my ($ref, $alt) = ($t[3], $1); my ($b, $q); $q = $1 if ($t[7] =~ /FQ=(-?[\d\.]+)/); if ($q < 0) { $_ = ($t[7] =~ /AF1=([\d\.]+)/)? $1 : 0; $b = ($_ < .5 || $alt eq '.')? $ref : $alt; $q = -$q; } else { $b = $het{"$ref$alt"}; $b ||= 'N'; } $b = lc($b); $b = uc($b) if (($t[7] =~ /MQ=(\d+)/ && $1 >= $_Q) && ($t[7] =~ /DP=(\d+)/ && $1 >= $_d && $1 <= $_D)); $q = int($q + 33 + .499); $q = chr($q <= 126? $q : 126); $seq .= $b; $qual .= $q; } elsif ($t[4] ne '.') { # an INDEL push(@gaps, [$t[1], length($t[3])]); } $last_pos = $t[1]; } &v2q_post_process($last_chr, \$seq, \$qual, \@gaps, $opts{l}); } sub v2q_post_process { my ($chr, $seq, $qual, $gaps, $l) = @_; for my $g (@$gaps) { my $beg = $g->[0] > $l? $g->[0] - $l : 0; my $end = $g->[0] + $g->[1] + $l; $end = length($$seq) if ($end > length($$seq)); substr($$seq, $beg, $end - $beg) = lc(substr($$seq, $beg, $end - $beg)); } print "\@$chr\n"; &v2q_print_str($seq); print "+\n"; &v2q_print_str($qual); } sub v2q_print_str { my ($s) = @_; my $l = length($$s); for (my $i = 0; $i < $l; $i += 60) { print substr($$s, $i, 60), "\n"; } } sub usage { die(qq/ Usage: vcfutils.pl []\n Command: subsam get a subset of samples listsam list the samples fillac fill the allele count field qstats SNP stats stratified by QUAL hapmap2vcf convert the hapmap format to VCF ucscsnp2vcf convert UCSC SNP SQL dump to VCF varFilter filtering short variants (*) vcf2fq VCF->fastq (**) Notes: Commands with description endting with (*) may need bcftools specific annotations. \n/); } bcftools-1.21/mpileup.c000066400000000000000000002410461467060157400151100ustar00rootroot00000000000000/* mpileup.c -- mpileup subcommand. Previously bam_plcmd.c from samtools Copyright (C) 2008-2024 Genome Research Ltd. Portions copyright (C) 2009-2012 Broad Institute. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "regidx.h" #include "bcftools.h" #include "bam2bcf.h" #include "bam_sample.h" #include "gvcf.h" #define MPLP_BCF 1 #define MPLP_VCF (1<<1) #define MPLP_NO_COMP (1<<2) #define MPLP_NO_ORPHAN (1<<3) #define MPLP_REALN (1<<4) #define MPLP_NO_INDEL (1<<5) #define MPLP_REDO_BAQ (1<<6) #define MPLP_ILLUMINA13 (1<<7) #define MPLP_IGNORE_RG (1<<8) #define MPLP_PRINT_POS (1<<9) #define MPLP_PRINT_MAPQ (1<<10) #define MPLP_PER_SAMPLE (1<<11) #define MPLP_SMART_OVERLAPS (1<<12) #define MPLP_REALN_PARTIAL (1<<13) typedef struct _mplp_aux_t mplp_aux_t; typedef struct _mplp_pileup_t mplp_pileup_t; // Data shared by all bam files typedef struct { int min_mq, flag, min_baseQ, max_baseQ, delta_baseQ, capQ_thres, max_depth, max_indel_depth, max_read_len, ambig_reads; uint32_t fmt_flag; int rflag_skip_any_unset, rflag_skip_all_unset, rflag_skip_any_set, rflag_skip_all_set, output_type; int openQ, extQ, tandemQ, min_support, indel_win_size; // for indels int seqQ_offset; double min_frac; // for indels double indel_bias, poly_mqual; double del_bias; // compensate for diff deletion vs insertion error rates double vs_ref; char *reg_fname, *pl_list, *fai_fname, *output_fname; int reg_is_file, record_cmd_line, n_threads, clevel; faidx_t *fai; regidx_t *bed, *reg; // bed: skipping regions, reg: index-jump to regions regitr_t *bed_itr, *reg_itr; int bed_logic; // 1: include region, 0: exclude region gvcf_t *gvcf; // auxiliary structures for calling bcf_callaux_t *bca; bcf_callret1_t *bcr; bcf_call_t bc; bam_mplp_t iter; mplp_aux_t **mplp_data; int nfiles; char **files; mplp_pileup_t *gplp; int *n_plp; const bam_pileup1_t **plp; bam_smpl_t *bsmpl; kstring_t buf; bcf1_t *bcf_rec; htsFile *bcf_fp; bcf_hdr_t *bcf_hdr; int indels_v20; int edlib; int argc; char **argv; int write_index; char *index_fn; } mplp_conf_t; typedef struct { char *ref[2]; int ref_id[2]; int ref_len[2]; } mplp_ref_t; #define MPLP_REF_INIT {{NULL,NULL},{-1,-1},{0,0}} // Data specific to each bam file struct _mplp_aux_t { samFile *fp; hts_itr_t *iter; bam_hdr_t *h; mplp_ref_t *ref; const mplp_conf_t *conf; int bam_id; hts_idx_t *idx; // maintained only with more than one -r regions }; // Data passed to htslib/mpileup struct _mplp_pileup_t { int n; int *n_plp, *m_plp; bam_pileup1_t **plp; }; static int mplp_get_ref(mplp_aux_t *ma, int tid, char **ref, int *ref_len) { mplp_ref_t *r = ma->ref; //printf("get ref %d {%d/%p, %d/%p}\n", tid, r->ref_id[0], r->ref[0], r->ref_id[1], r->ref[1]); if (!r || !ma->conf->fai) { *ref = NULL; return 0; } // Do we need to reference count this so multiple mplp_aux_t can // track which references are in use? // For now we just cache the last two. Sufficient? if (tid == r->ref_id[0]) { *ref = r->ref[0]; *ref_len = r->ref_len[0]; return 1; } if (tid == r->ref_id[1]) { // Last, swap over int tmp; tmp = r->ref_id[0]; r->ref_id[0] = r->ref_id[1]; r->ref_id[1] = tmp; tmp = r->ref_len[0]; r->ref_len[0] = r->ref_len[1]; r->ref_len[1] = tmp; char *tc; tc = r->ref[0]; r->ref[0] = r->ref[1]; r->ref[1] = tc; *ref = r->ref[0]; *ref_len = r->ref_len[0]; return 1; } // New, so migrate to old and load new free(r->ref[1]); r->ref[1] = r->ref[0]; r->ref_id[1] = r->ref_id[0]; r->ref_len[1] = r->ref_len[0]; r->ref_id[0] = tid; r->ref[0] = faidx_fetch_seq(ma->conf->fai, ma->h->target_name[r->ref_id[0]], 0, INT_MAX, &r->ref_len[0]); if (!r->ref[0]) { r->ref[0] = NULL; r->ref_id[0] = -1; r->ref_len[0] = 0; *ref = NULL; return 0; } *ref = r->ref[0]; *ref_len = r->ref_len[0]; return 1; } static int mplp_func(void *data, bam1_t *b) { char *ref; mplp_aux_t *ma = (mplp_aux_t*)data; int ret, ref_len; while (1) { int has_ref; ret = ma->iter? sam_itr_next(ma->fp, ma->iter, b) : sam_read1(ma->fp, ma->h, b); if (ret < 0) break; // The 'B' cigar operation is not part of the specification, considering as obsolete. // bam_remove_B(b); if (b->core.tid < 0 || (b->core.flag&BAM_FUNMAP)) continue; // exclude unmapped reads if (ma->conf->rflag_skip_any_unset && (ma->conf->rflag_skip_any_unset&b->core.flag)!=ma->conf->rflag_skip_any_unset) continue; if (ma->conf->rflag_skip_all_set && (ma->conf->rflag_skip_all_set&b->core.flag)==ma->conf->rflag_skip_all_set) continue; if (ma->conf->rflag_skip_all_unset && !(ma->conf->rflag_skip_all_unset&b->core.flag)) continue; if (ma->conf->rflag_skip_any_set && ma->conf->rflag_skip_any_set&b->core.flag) continue; if (ma->conf->bed) { // test overlap regitr_t *itr = ma->conf->bed_itr; int beg = b->core.pos, end = bam_endpos(b)-1; int overlap = regidx_overlap(ma->conf->bed, ma->h->target_name[b->core.tid],beg,end, itr); if ( !ma->conf->bed_logic && !overlap ) { // exclude only reads which are fully contained in the region while ( regitr_overlap(itr) ) { if ( beg < itr->beg ) { overlap = 1; break; } if ( end > itr->end ) { overlap = 1; break; } } } if ( !overlap ) continue; } if ( bam_smpl_get_sample_id(ma->conf->bsmpl,ma->bam_id,b)<0 ) continue; if (ma->conf->flag & MPLP_ILLUMINA13) { int i; uint8_t *qual = bam_get_qual(b); for (i = 0; i < b->core.l_qseq; ++i) qual[i] = qual[i] > 31? qual[i] - 31 : 0; } if (ma->conf->fai && b->core.tid >= 0) { has_ref = mplp_get_ref(ma, b->core.tid, &ref, &ref_len); if (has_ref && ref_len <= b->core.pos) { // exclude reads outside of the reference sequence fprintf(stderr,"[%s] Skipping because %"PRId64" is outside of %d [ref:%d]\n", __func__, (int64_t) b->core.pos, ref_len, b->core.tid); continue; } } else { has_ref = 0; } // Allow sufficient room for bam_aux_append of ZQ tag without // a realloc and consequent breakage of pileup's cached pointers. if (has_ref && (ma->conf->flag &MPLP_REALN) && !bam_aux_get(b, "ZQ")) { // Doing sam_prob_realn later is problematic as it adds to // the tag list (ZQ or BQ), which causes a realloc of b->data. // This happens after pileup has built a hash table on the // read name. It's a deficiency in pileup IMO. // We could implement a new sam_prob_realn that returns ZQ // somewhere else and cache it ourselves (pileup clientdata), // but for now we simply use a workaround. // // We create a fake tag of the correct length, which we remove // just prior calling sam_prob_realn so we can guarantee there is // room. (We can't just make room now as bam_copy1 removes it // again). if (b->core.l_qseq > 500) { uint8_t *ZQ = malloc((uint32_t)b->core.l_qseq+1); memset(ZQ, '@', b->core.l_qseq); ZQ[b->core.l_qseq] = 0; bam_aux_append(b, "_Q", 'Z', b->core.l_qseq+1, ZQ); free(ZQ); } else { static uint8_t ZQ[501] = "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@" "@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@"; ZQ[b->core.l_qseq] = 0; bam_aux_append(b, "_Q", 'Z', b->core.l_qseq+1, ZQ); ZQ[b->core.l_qseq] = '@'; } } if (has_ref && ma->conf->capQ_thres > 10) { int q = sam_cap_mapq(b, ref, ref_len, ma->conf->capQ_thres); if (q < 0) continue; // skip else if (b->core.qual > q) b->core.qual = q; } if (b->core.qual < ma->conf->min_mq) continue; else if ((ma->conf->flag&MPLP_NO_ORPHAN) && (b->core.flag&BAM_FPAIRED) && !(b->core.flag&BAM_FPROPER_PAIR)) continue; return ret; }; return ret; } // Called once per new bam added to the pileup. // We cache sample information here so we don't have to keep recomputing this // on each and every pileup column. If FMT/SCR annotation is requested, a flag // is set to indicate the presence of a soft clip. static int pileup_constructor(void *data, const bam1_t *b, bam_pileup_cd *cd) { cd->p = calloc(1,sizeof(plp_cd_t)); PLP_NM(cd) = PLP_NM_UNSET; mplp_aux_t *ma = (mplp_aux_t *)data; int n = bam_smpl_get_sample_id(ma->conf->bsmpl, ma->bam_id, (bam1_t *)b); PLP_SET_SAMPLE_ID(cd, n); // Whether read has a soft-clip is used in mplp_realn's heuristics. // TODO: consider whether clip length is beneficial to use? int i; for (i=0; icore.n_cigar; i++) { int cig = bam_get_cigar(b)[i] & BAM_CIGAR_MASK; if (cig == BAM_CSOFT_CLIP) { PLP_SET_SOFT_CLIP(cd); break; } } if (ma->conf->flag & MPLP_REALN) { int i; // int tot_ins = 0; // int p = 0; uint32_t *cigar = bam_get_cigar(b); for (i=0; icore.n_cigar; i++) { int cig = cigar[i] & BAM_CIGAR_MASK; // if (bam_cigar_type(cig) & 2) // p += cigar[i] >> BAM_CIGAR_SHIFT; if (cig == BAM_CINS || cig == BAM_CDEL || cig == BAM_CREF_SKIP) { // tot_ins += cigar[i] >> BAM_CIGAR_SHIFT; // Possible further optimsation, check tot_ins==1 later // (and remove break) so we can detect single bp indels. // We may want to focus BAQ on more complex regions only. PLP_SET_INDEL(cd); break; } // TODO: proper p->cd struct and have cd->i as a size rather // than a flag. // Then aggregate together the sizes and if just 1 size for all // reads or 2 sizes for approx 50/50 split in all reads, then // treat this as a well-aligned variant and don't run BAQ. } } return 0; } static int pileup_destructor(void *data, const bam1_t *b, bam_pileup_cd *cd) { free(cd->p); return 0; } static void group_smpl(mplp_pileup_t *m, bam_smpl_t *bsmpl, int n, int *n_plp, const bam_pileup1_t **plp) { int i, j; memset(m->n_plp, 0, m->n * sizeof(int)); for (i = 0; i < n; ++i) // iterate over all bams { for (j = 0; j < n_plp[i]; ++j) // iterate over all reads available at this position { const bam_pileup1_t *p = plp[i] + j; int id = PLP_SAMPLE_ID(&(p->cd)); if (m->n_plp[id] == m->m_plp[id]) { m->m_plp[id] = m->m_plp[id]? m->m_plp[id]<<1 : 8; m->plp[id] = (bam_pileup1_t*) realloc(m->plp[id], sizeof(bam_pileup1_t) * m->m_plp[id]); } m->plp[id][m->n_plp[id]++] = *p; } } } static void flush_bcf_records(mplp_conf_t *conf, htsFile *fp, bcf_hdr_t *hdr, bcf1_t *rec) { if ( !conf->gvcf ) { if ( rec && bcf_write1(fp, hdr, rec)!=0 ) error("[%s] Error: failed to write the record to %s\n", __func__,conf->output_fname?conf->output_fname:"standard output"); return; } if ( !rec ) { gvcf_write(conf->gvcf, fp, hdr, NULL, 0); return; } int is_ref = 0; if ( rec->n_allele==1 ) is_ref = 1; else if ( rec->n_allele==2 ) { // second allele is mpileup's X, not a variant if ( rec->d.allele[1][0]=='<' && rec->d.allele[1][1]=='*' && rec->d.allele[1][2]=='>' ) is_ref = 1; } rec = gvcf_write(conf->gvcf, fp, hdr, rec, is_ref); if ( rec && bcf_write1(fp,hdr,rec)!=0 ) error("[%s] Error: failed to write the record to %s\n", __func__,conf->output_fname?conf->output_fname:"standard output"); } /* * Loops for an indel at this position. * * Only reads that overlap an indel loci get realigned. This considerably * reduces the cost of running BAQ while keeping the main benefits. * * TODO: also consider only realigning reads that don't span the indel * by more than a certain amount either-side. Ie focus BAQ only on reads * ending adjacent to the indel, where the alignment is most likely to * be wrong. (2nd TODO: do this based on sequence context; STRs bad, unique * data good.) * * NB: this may sadly realign after we've already used the data. Hmm... */ static void mplp_realn(int n, int *n_plp, const bam_pileup1_t **plp, int flag, int max_read_len, char *ref, int ref_len, int pos) { int i, j, has_indel = 0, has_clip = 0, nt = 0; int min_indel = INT_MAX, max_indel = INT_MIN; // Is an indel present. // NB: don't bother even checking if very long as almost guaranteed // to have indel (and likely soft-clips too). for (i = 0; i < n; i++) { // iterate over bams nt += n_plp[i]; for (j = 0; j < n_plp[i]; j++) { // iterate over reads bam_pileup1_t *p = (bam_pileup1_t *)plp[i] + j; has_indel += (PLP_HAS_INDEL(&p->cd) || p->indel) ? 1 : 0; // Has_clip is almost always true for very long reads // (eg PacBio CCS), but these rarely matter as the clip // is likely a long way from this indel. has_clip += (PLP_HAS_SOFT_CLIP(&p->cd)) ? 1 : 0; if (max_indel < p->indel) max_indel = p->indel; if (min_indel > p->indel) min_indel = p->indel; } } if (flag & MPLP_REALN_PARTIAL) { if (has_indel == 0 || (has_clip < 0.2*nt && max_indel == min_indel && (has_indel < 0.1*nt /*|| has_indel > 0.9*nt*/ || has_indel == 1))) return; } // Realign for (i = 0; i < n; i++) { // iterate over bams for (j = 0; j < n_plp[i]; j++) { // iterate over reads const bam_pileup1_t *p = plp[i] + j; bam1_t *b = p->b; // Avoid doing multiple times. // // Note we cannot modify p->cd.i here with a PLP_SET macro // because the cd item is held by mpileup in an lbnode_t // struct and copied over to the pileup struct for each // iteration, essentially making p->cd.i read only. // // We could use our own structure (p->cd.p), allocated during // the constructor, but for simplicity we play dirty and // abuse an unused flag bit instead. if ( PLP_IS_REALN(&(p->cd)) ) continue; PLP_SET_REALN(&(p->cd)); if (b->core.l_qseq > max_read_len) continue; // Check p->cigar_ind and see what cigar elements are before // and after. How close is this location to the end of the // read? Only realign if we don't span by more than X bases. // // Again, best only done on deeper data as BAQ helps // disproportionately more on shallow data sets. // // This rescues some of the false negatives that are caused by // systematic reduction in quality due to sample vs ref alignment. // At deep coverage we skip realigning more reads as we have sufficient depth. // This rescues for false negatives. At shallow depth we pay for this with // more FP so are more stringent on spanning size. #define REALN_DIST (40+10*(nt<40)+10*(nt<20)) uint32_t *cig = bam_get_cigar(b); int ncig = b->core.n_cigar; // Don't realign reads where indel is in middle? // On long read data we don't care about soft-clips at the ends. // For short read data, we always calc BAQ on these as they're // a common source of false positives. if ((flag & MPLP_REALN_PARTIAL) && nt > 15 && ncig > 1) { // Left & right cigar op match. int lr = b->core.l_qseq > 500; int lm = 0, rm = 0, k, nm = 0; for (k = 0; k < ncig; k++) { int cop = bam_cigar_op(cig[k]); if (lr && (cop == BAM_CHARD_CLIP || cop == BAM_CSOFT_CLIP)) continue; if (cop == BAM_CMATCH || cop == BAM_CDIFF || cop == BAM_CEQUAL) { lm += bam_cigar_oplen(cig[k]); nm++; } else { break; } } // if everything is a match (or sequence (mis)match) then move on // because we don't have an indel in the middle if (nm != ncig) { for (k = ncig-1; k >= 0; k--) { int cop = bam_cigar_op(cig[k]); if (lr && (cop == BAM_CHARD_CLIP || cop == BAM_CSOFT_CLIP)) continue; if (cop == BAM_CMATCH || cop == BAM_CDIFF || cop == BAM_CEQUAL) rm += bam_cigar_oplen(cig[k]); else break; } if (lm >= REALN_DIST*4 && rm >= REALN_DIST*4) continue; if (lm >= REALN_DIST && rm >= REALN_DIST && has_clip < (0.15+0.05*(nt>20))*nt) continue; } } if (b->core.l_qseq > 500) { // don't do BAQ on long-read data if it's going to // cause us to have a large band-with and costly in CPU int rl = bam_cigar2rlen(b->core.n_cigar, bam_get_cigar(b)); if (abs(rl - b->core.l_qseq) * b->core.l_qseq >= 500000) continue; } // Fudge: make room for ZQ tag. uint8_t *_Q = bam_aux_get(b, "_Q"); if (_Q) bam_aux_del(b, _Q); sam_prob_realn(b, ref, ref_len, (flag & MPLP_REDO_BAQ) ? 7 : 3); } } return; } static int mpileup_reg(mplp_conf_t *conf, uint32_t beg, uint32_t end) { bam_hdr_t *hdr = conf->mplp_data[0]->h; // header of first file in input list int ret, i, tid, pos, ref_len; char *ref; while ( (ret=bam_mplp_auto(conf->iter, &tid, &pos, conf->n_plp, conf->plp)) > 0) { if ( posend ) continue; if ( conf->bed && tid >= 0 ) { int overlap = regidx_overlap(conf->bed, hdr->target_name[tid], pos, pos, NULL); if ( !conf->bed_logic ) overlap = overlap ? 0 : 1; if ( !overlap ) continue; } int has_ref = mplp_get_ref(conf->mplp_data[0], tid, &ref, &ref_len); if (has_ref && (conf->flag & MPLP_REALN)) mplp_realn(conf->nfiles, conf->n_plp, conf->plp, conf->flag, conf->max_read_len, ref, ref_len, pos); int total_depth, _ref0, ref16; for (i = total_depth = 0; i < conf->nfiles; ++i) total_depth += conf->n_plp[i]; group_smpl(conf->gplp, conf->bsmpl, conf->nfiles, conf->n_plp, conf->plp); _ref0 = (ref && pos < ref_len)? ref[pos] : 'N'; ref16 = seq_nt16_table[_ref0]; bcf_callaux_clean(conf->bca, &conf->bc); for (i = 0; i < conf->gplp->n; ++i) bcf_call_glfgen(conf->gplp->n_plp[i], conf->gplp->plp[i], ref16, conf->bca, conf->bcr + i); conf->bc.tid = tid; conf->bc.pos = pos; bcf_call_combine(conf->gplp->n, conf->bcr, conf->bca, ref16, &conf->bc); bcf_clear1(conf->bcf_rec); bcf_call2bcf(&conf->bc, conf->bcf_rec, conf->bcr, conf->fmt_flag, conf->bca, 0); flush_bcf_records(conf, conf->bcf_fp, conf->bcf_hdr, conf->bcf_rec); // call indels; todo: subsampling with total_depth>max_indel_depth instead of ignoring? // check me: rghash in bcf_call_gap_prep() should have no effect, reads mplp_func already excludes them if (!(conf->flag&MPLP_NO_INDEL) && total_depth < conf->max_indel_depth) { bcf_callaux_clean(conf->bca, &conf->bc); conf->bca->chr = tid>=0 ? hdr->target_name[tid] : NULL; int iret; if (conf->edlib) iret = bcf_edlib_gap_prep(conf->gplp->n, conf->gplp->n_plp, conf->gplp->plp, pos, conf->bca, ref, ref_len); else if ( conf->indels_v20 ) iret = bcf_iaux_gap_prep(conf->gplp->n, conf->gplp->n_plp, conf->gplp->plp, pos, conf->bca, ref); else iret = bcf_call_gap_prep(conf->gplp->n, conf->gplp->n_plp, conf->gplp->plp, pos, conf->bca, ref); if ( iret>=0 ) { for (i = 0; i < conf->gplp->n; ++i) bcf_call_glfgen(conf->gplp->n_plp[i], conf->gplp->plp[i], -1, conf->bca, conf->bcr + i); if (bcf_call_combine(conf->gplp->n, conf->bcr, conf->bca, -1, &conf->bc) >= 0) { bcf_clear1(conf->bcf_rec); bcf_call2bcf(&conf->bc, conf->bcf_rec, conf->bcr, conf->fmt_flag, conf->bca, ref); flush_bcf_records(conf, conf->bcf_fp, conf->bcf_hdr, conf->bcf_rec); } } } } return ret; } static int mpileup(mplp_conf_t *conf) { if (conf->nfiles == 0) { fprintf(stderr,"[%s] no input file/data given\n", __func__); exit(EXIT_FAILURE); } mplp_ref_t mp_ref = MPLP_REF_INIT; conf->gplp = (mplp_pileup_t *) calloc(1,sizeof(mplp_pileup_t)); conf->mplp_data = (mplp_aux_t**) calloc(conf->nfiles, sizeof(mplp_aux_t*)); conf->plp = (const bam_pileup1_t**) calloc(conf->nfiles, sizeof(bam_pileup1_t*)); conf->n_plp = (int*) calloc(conf->nfiles, sizeof(int)); // Allow to run mpileup on multiple regions in one go. This comes at cost: the bai index // must be kept in the memory for the whole time which can be a problem with many bams. // Therefore if none or only one region is requested, we initialize the bam iterator as // before and free the index. Only when multiple regions are queried, we keep the index. int nregs = 0; if ( conf->reg_fname ) { if ( conf->reg_is_file ) { conf->reg = regidx_init(conf->reg_fname,NULL,NULL,0,NULL); if ( !conf->reg ) { fprintf(stderr,"Could not parse the regions: %s\n", conf->reg_fname); exit(EXIT_FAILURE); } } else { conf->reg = regidx_init(NULL,regidx_parse_reg,NULL,sizeof(char*),NULL); if ( regidx_insert_list(conf->reg,conf->reg_fname,',') !=0 ) { fprintf(stderr,"Could not parse the regions: %s\n", conf->reg_fname); exit(EXIT_FAILURE); } } nregs = regidx_nregs(conf->reg); if ( nregs ) { // the regions list can be empty, see #2250 conf->reg_itr = regitr_init(conf->reg); regitr_loop(conf->reg_itr); // region iterator now positioned at the first region } } // read the header of each file in the list and initialize data // beware: mpileup has always assumed that tid's are consistent in the headers, add sanity check at least! bam_hdr_t *hdr = NULL; // header of first file in input list int i; for (i = 0; i < conf->nfiles; ++i) { bam_hdr_t *h_tmp; conf->mplp_data[i] = (mplp_aux_t*) calloc(1, sizeof(mplp_aux_t)); conf->mplp_data[i]->fp = sam_open(conf->files[i], "rb"); if ( !conf->mplp_data[i]->fp ) { fprintf(stderr, "[%s] failed to open %s: %s\n", __func__, conf->files[i], strerror(errno)); exit(EXIT_FAILURE); } if (hts_set_opt(conf->mplp_data[i]->fp, CRAM_OPT_DECODE_MD, 1)) { fprintf(stderr, "Failed to set CRAM_OPT_DECODE_MD value\n"); exit(EXIT_FAILURE); } if (conf->fai_fname && hts_set_fai_filename(conf->mplp_data[i]->fp, conf->fai_fname) != 0) { fprintf(stderr, "[%s] failed to process %s: %s\n", __func__, conf->fai_fname, strerror(errno)); exit(EXIT_FAILURE); } conf->mplp_data[i]->conf = conf; conf->mplp_data[i]->ref = &mp_ref; h_tmp = sam_hdr_read(conf->mplp_data[i]->fp); if ( !h_tmp ) { fprintf(stderr,"[%s] fail to read the header of %s\n", __func__, conf->files[i]); exit(EXIT_FAILURE); } conf->mplp_data[i]->h = i ? hdr : h_tmp; // for j==0, "h" has not been set yet conf->mplp_data[i]->bam_id = bam_smpl_add_bam(conf->bsmpl,h_tmp->text,conf->files[i]); if ( conf->mplp_data[i]->bam_id<0 ) { // no usable readgroups in this bam, it can be skipped sam_close(conf->mplp_data[i]->fp); free(conf->mplp_data[i]); bam_hdr_destroy(h_tmp); free(conf->files[i]); if ( i+1nfiles ) memmove(&conf->files[i],&conf->files[i+1],sizeof(*conf->files)*(conf->nfiles-i-1)); conf->nfiles--; i--; continue; } if (conf->reg && nregs) { hts_idx_t *idx = sam_index_load(conf->mplp_data[i]->fp, conf->files[i]); if (idx == NULL) { fprintf(stderr, "[%s] fail to load index for %s\n", __func__, conf->files[i]); exit(EXIT_FAILURE); } conf->buf.l = 0; ksprintf(&conf->buf,"%s:%u-%u",conf->reg_itr->seq,conf->reg_itr->beg+1,conf->reg_itr->end+1); conf->mplp_data[i]->iter = sam_itr_querys(idx, conf->mplp_data[i]->h, conf->buf.s); if ( !conf->mplp_data[i]->iter ) { conf->mplp_data[i]->iter = sam_itr_querys(idx, conf->mplp_data[i]->h, conf->reg_itr->seq); if ( conf->mplp_data[i]->iter ) { fprintf(stderr,"[E::%s] fail to parse region '%s'\n", __func__, conf->buf.s); exit(EXIT_FAILURE); } fprintf(stderr,"[E::%s] the sequence \"%s\" not found: %s\n",__func__,conf->reg_itr->seq,conf->files[i]); exit(EXIT_FAILURE); } if ( nregs==1 ) // no need to keep the index in memory hts_idx_destroy(idx); else conf->mplp_data[i]->idx = idx; } if ( !hdr ) hdr = h_tmp; /* save the header of first file in list */ else { // FIXME: check consistency between h and h_tmp bam_hdr_destroy(h_tmp); // we store only the first file's header; it's (alleged to be) // compatible with the i-th file's target_name lookup needs conf->mplp_data[i]->h = hdr; } } if ( !hdr ) { fprintf(stderr, "[%s] failed to find a file header with usable read groups\n", __func__); exit(EXIT_FAILURE); } // allocate data storage proportionate to number of samples being studied sm->n bam_smpl_get_samples(conf->bsmpl, &conf->gplp->n); conf->gplp->n_plp = (int*) calloc(conf->gplp->n, sizeof(int)); conf->gplp->m_plp = (int*) calloc(conf->gplp->n, sizeof(int)); conf->gplp->plp = (bam_pileup1_t**) calloc(conf->gplp->n, sizeof(bam_pileup1_t*)); fprintf(stderr, "[%s] %d samples in %d input files\n", __func__, conf->gplp->n, conf->nfiles); // write the VCF header char wmode[8]; set_wmode(wmode,conf->output_type,conf->output_fname,conf->clevel); conf->bcf_fp = hts_open(conf->output_fname ? conf->output_fname : "-", wmode); if (conf->bcf_fp == NULL) { fprintf(stderr, "[%s] failed to write to %s: %s\n", __func__, conf->output_fname? conf->output_fname : "standard output", strerror(errno)); exit(EXIT_FAILURE); } if ( conf->n_threads ) hts_set_threads(conf->bcf_fp, conf->n_threads); // BCF header creation conf->bcf_hdr = bcf_hdr_init("w"); conf->buf.l = 0; if (conf->record_cmd_line) { ksprintf(&conf->buf, "##bcftoolsVersion=%s+htslib-%s\n",bcftools_version(),hts_version()); bcf_hdr_append(conf->bcf_hdr, conf->buf.s); conf->buf.l = 0; ksprintf(&conf->buf, "##bcftoolsCommand=mpileup"); for (i=1; iargc; i++) ksprintf(&conf->buf, " %s", conf->argv[i]); kputc('\n', &conf->buf); bcf_hdr_append(conf->bcf_hdr, conf->buf.s); } if (conf->fai_fname) { conf->buf.l = 0; ksprintf(&conf->buf, "##reference=file://%s\n", conf->fai_fname); bcf_hdr_append(conf->bcf_hdr, conf->buf.s); } // Translate BAM @SQ tags to BCF ##contig tags // todo: use/write new BAM header manipulation routines, fill also UR, M5 for (i=0; in_targets; i++) { conf->buf.l = 0; ksprintf(&conf->buf, "##contig=", hdr->target_name[i], hdr->target_len[i]); bcf_hdr_append(conf->bcf_hdr, conf->buf.s); } conf->buf.l = 0; bcf_hdr_append(conf->bcf_hdr,"##ALT="); bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_IDV ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_IMF ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_VDB ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_RPBZ ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_MQBZ ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_BQBZ ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_MQSBZ ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_MIN_PL_SUM ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_NM ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_NMBZ ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_FMT_NMBZ ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_INFO_SCBZ ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_FS ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_SGB ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_MQ0F ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); bcf_hdr_append(conf->bcf_hdr,"##INFO="); bcf_hdr_append(conf->bcf_hdr,"##INFO="); bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_DP ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_DV ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_DPR ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_INFO_DPR ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_FMT_DP4 ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_SP ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_AD ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_ADF ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_ADR ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_FMT_QS ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_INFO_AD ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_ADF ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_INFO_SCR ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->fmt_flag&B2B_FMT_SCR ) bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); if ( conf->fmt_flag&B2B_INFO_ADR ) bcf_hdr_append(conf->bcf_hdr,"##INFO="); if ( conf->gvcf ) gvcf_update_header(conf->gvcf, conf->bcf_hdr); int nsmpl; const char **smpl = bam_smpl_get_samples(conf->bsmpl, &nsmpl); for (i=0; ibcf_hdr, smpl[i]); if ( bcf_hdr_write(conf->bcf_fp, conf->bcf_hdr)!=0 ) error("[%s] Error: failed to write the header to %s\n",__func__,conf->output_fname?conf->output_fname:"standard output"); if ( init_index2(conf->bcf_fp,conf->bcf_hdr,conf->output_fname, &conf->index_fn, conf->write_index) < 0 ) error("Error: failed to initialise index for %s\n",conf->output_fname); conf->bca = bcf_call_init(-1., conf->min_baseQ, conf->max_baseQ, conf->delta_baseQ); conf->bcr = (bcf_callret1_t*) calloc(nsmpl, sizeof(bcf_callret1_t)); conf->bca->openQ = conf->openQ, conf->bca->extQ = conf->extQ, conf->bca->tandemQ = conf->tandemQ; conf->bca->indel_bias = conf->indel_bias; conf->bca->del_bias = conf->del_bias; conf->bca->min_frac = conf->min_frac; conf->bca->min_support = conf->min_support; conf->bca->per_sample_flt = conf->flag & MPLP_PER_SAMPLE; conf->bca->fmt_flag = conf->fmt_flag; conf->bca->ambig_reads = conf->ambig_reads; conf->bca->indel_win_size = conf->indel_win_size; conf->bca->indels_v20 = conf->indels_v20; conf->bca->edlib = conf->edlib; conf->bca->seqQ_offset = conf->seqQ_offset; conf->bca->poly_mqual = conf->poly_mqual; conf->bca->vs_ref = conf->vs_ref; conf->bc.bcf_hdr = conf->bcf_hdr; conf->bc.n = nsmpl; conf->bc.PL = (int32_t*) malloc(15 * nsmpl * sizeof(*conf->bc.PL)); conf->bc.QS = (int32_t*) malloc(nsmpl*sizeof(*conf->bc.QS)*B2B_MAX_ALLELES); for (i=0; ibcr[i].QS = conf->bc.QS + i*B2B_MAX_ALLELES; if (conf->fmt_flag) { assert( sizeof(float)==sizeof(int32_t) ); conf->bc.DP4 = (int32_t*) malloc(nsmpl * sizeof(int32_t) * 4); conf->bc.fmt_arr = (uint8_t*) malloc(nsmpl * sizeof(float)); // all fmt_flag fields, float and int32 if ( conf->fmt_flag&(B2B_INFO_DPR|B2B_FMT_DPR|B2B_INFO_AD|B2B_INFO_ADF|B2B_INFO_ADR|B2B_FMT_AD|B2B_FMT_ADF|B2B_FMT_ADR) ) { // first B2B_MAX_ALLELES fields for total numbers, the rest per-sample conf->bc.ADR = (int32_t*) malloc((nsmpl+1)*B2B_MAX_ALLELES*sizeof(int32_t)); conf->bc.ADF = (int32_t*) malloc((nsmpl+1)*B2B_MAX_ALLELES*sizeof(int32_t)); for (i=0; ibcr[i].ADR = conf->bc.ADR + (i+1)*B2B_MAX_ALLELES; conf->bcr[i].ADF = conf->bc.ADF + (i+1)*B2B_MAX_ALLELES; } } if ( conf->fmt_flag&(B2B_INFO_SCR|B2B_FMT_SCR) ) conf->bc.SCR = (int32_t*) malloc((nsmpl+1)*sizeof(*conf->bc.SCR)); } int nnmbz = (conf->fmt_flag&B2B_FMT_NMBZ) ? nsmpl + 1 : 1; conf->bc.ref_nm = (int32_t*) malloc(sizeof(*conf->bc.ref_nm) * nnmbz * B2B_N_NM); conf->bc.alt_nm = (int32_t*) malloc(sizeof(*conf->bc.alt_nm) * nnmbz * B2B_N_NM); conf->bc.mwu_nm = (float*) malloc((nsmpl+1)*sizeof(*conf->bc.mwu_nm)); conf->bca->ref_nm = conf->bc.ref_nm; // this is just to make the arrays available in bcf_call_glfgen() conf->bca->alt_nm = conf->bc.alt_nm; if ( conf->fmt_flag&B2B_FMT_NMBZ ) { for (i=0; ibcr[i].ref_nm = conf->bc.ref_nm + (i+1)*B2B_N_NM; for (i=0; ibcr[i].alt_nm = conf->bc.alt_nm + (i+1)*B2B_N_NM; } // init mpileup conf->iter = bam_mplp_init(conf->nfiles, mplp_func, (void**)conf->mplp_data); if ( conf->flag & MPLP_SMART_OVERLAPS ) bam_mplp_init_overlaps(conf->iter); fprintf(stderr, "[%s] maximum number of reads per input file set to -d %d\n", __func__, conf->max_depth); if ( (double)conf->max_depth * conf->nfiles > 1<<20) fprintf(stderr, "Warning: Potential memory hog, up to %.0fM reads in the pileup!\n", (double)conf->max_depth*conf->nfiles); if ( (double)conf->max_depth * conf->nfiles / nsmpl < 250 ) fprintf(stderr, "Note: The maximum per-sample depth with -d %d is %.1fx\n", conf->max_depth,(double)conf->max_depth * conf->nfiles / nsmpl); bam_mplp_set_maxcnt(conf->iter, conf->max_depth); conf->max_indel_depth = conf->max_indel_depth * nsmpl; conf->bcf_rec = bcf_init1(); bam_mplp_constructor(conf->iter, pileup_constructor); bam_mplp_destructor(conf->iter, pileup_destructor); // Run mpileup for multiple regions int ret = 0; if ( nregs ) { int ireg = 0; do { // first region is already positioned if ( ireg++ > 0 ) { conf->buf.l = 0; ksprintf(&conf->buf,"%s:%u-%u",conf->reg_itr->seq,conf->reg_itr->beg+1,conf->reg_itr->end+1); for (i=0; infiles; i++) { hts_itr_destroy(conf->mplp_data[i]->iter); conf->mplp_data[i]->iter = sam_itr_querys(conf->mplp_data[i]->idx, conf->mplp_data[i]->h, conf->buf.s); if ( !conf->mplp_data[i]->iter ) { conf->mplp_data[i]->iter = sam_itr_querys(conf->mplp_data[i]->idx, conf->mplp_data[i]->h, conf->reg_itr->seq); if ( conf->mplp_data[i]->iter ) { fprintf(stderr,"[E::%s] fail to parse region '%s'\n", __func__, conf->buf.s); exit(EXIT_FAILURE); } fprintf(stderr,"[E::%s] the sequence \"%s\" not found: %s\n",__func__,conf->reg_itr->seq,conf->files[i]); exit(EXIT_FAILURE); } bam_mplp_reset(conf->iter); } } ret = mpileup_reg(conf,conf->reg_itr->beg,conf->reg_itr->end); if ( ret<0 ) break; } while ( regitr_loop(conf->reg_itr) ); } else if ( !conf->reg ) ret = mpileup_reg(conf,0,UINT32_MAX); if ( ret<0 ) { fprintf(stderr, "[%s] failed to read from input file\n", __func__); exit(EXIT_FAILURE); } flush_bcf_records(conf, conf->bcf_fp, conf->bcf_hdr, NULL); // clean up free(conf->bc.tmp.s); bcf_destroy1(conf->bcf_rec); if (conf->bcf_fp) { if ( conf->write_index ) { if ( bcf_idx_save(conf->bcf_fp)<0 ) { if ( hts_close(conf->bcf_fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,conf->output_fname); error("Error: cannot write to index %s\n",conf->index_fn); } free(conf->index_fn); } if ( hts_close(conf->bcf_fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,conf->output_fname); bcf_hdr_destroy(conf->bcf_hdr); bcf_call_destroy(conf->bca); free(conf->bc.PL); free(conf->bc.DP4); free(conf->bc.ADR); free(conf->bc.ADF); free(conf->bc.SCR); free(conf->bc.QS); free(conf->bc.ref_nm); free(conf->bc.alt_nm); free(conf->bc.fmt_arr); free(conf->bc.mwu_nm); free(conf->bcr); } if ( conf->gvcf ) gvcf_destroy(conf->gvcf); free(conf->buf.s); for (i = 0; i < conf->gplp->n; ++i) free(conf->gplp->plp[i]); free(conf->gplp->plp); free(conf->gplp->n_plp); free(conf->gplp->m_plp); free(conf->gplp); bam_mplp_destroy(conf->iter); bam_hdr_destroy(hdr); for (i = 0; i < conf->nfiles; ++i) { if ( nregs>1 ) hts_idx_destroy(conf->mplp_data[i]->idx); sam_close(conf->mplp_data[i]->fp); if ( conf->mplp_data[i]->iter) hts_itr_destroy(conf->mplp_data[i]->iter); free(conf->mplp_data[i]); } if ( conf->reg_itr ) regitr_destroy(conf->reg_itr); free(conf->mplp_data); free(conf->plp); free(conf->n_plp); free(mp_ref.ref[0]); free(mp_ref.ref[1]); return 0; } static int is_url(const char *s) { static const char uri_scheme_chars[] = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+.-"; return s[strspn(s, uri_scheme_chars)] == ':'; } #define MAX_PATH_LEN 1024 int read_file_list(const char *file_list,int *n,char **argv[]) { char buf[MAX_PATH_LEN]; int len, nfiles = 0; char **files = NULL; struct stat sb; *n = 0; *argv = NULL; FILE *fh = fopen(file_list,"r"); if ( !fh ) { fprintf(stderr,"%s: %s\n", file_list,strerror(errno)); return 1; } files = (char**) calloc(nfiles,sizeof(char*)); nfiles = 0; while ( fgets(buf,MAX_PATH_LEN,fh) ) { // allow empty lines and trailing spaces len = strlen(buf); while ( len>0 && isspace(buf[len-1]) ) len--; if ( !len ) continue; // check sanity of the file list buf[len] = 0; if (! (is_url(buf) || stat(buf, &sb) == 0)) { // no such file, check if it is safe to print its name int i, safe_to_print = 1; for (i=0; irflag_skip_all_set); char *tmp_skip_any_unset = bam_flag2str(mplp->rflag_skip_any_unset); char *tmp_skip_all_unset = bam_flag2str(mplp->rflag_skip_all_unset); char *tmp_skip_any_set = bam_flag2str(mplp->rflag_skip_any_set); // Display usage information, formatted for the standard 80 columns. // (The unusual string formatting here aids the readability of this // source code in 80 columns, to the extent that's possible.) fprintf(fp, "\n" "Usage: bcftools mpileup [options] in1.bam [in2.bam [...]]\n" "\n" "Input options:\n" " -6, --illumina1.3+ Quality is in the Illumina-1.3+ encoding\n" " -A, --count-orphans Include anomalous read pairs, with flag PAIRED but not PROPER_PAIR set\n" " -b, --bam-list FILE List of input BAM filenames, one per line\n" " -B, --no-BAQ Disable BAQ (per-Base Alignment Quality)\n" " -C, --adjust-MQ INT Adjust mapping quality [0]\n" " -D, --full-BAQ Apply BAQ everywhere, not just in problematic regions\n" " -d, --max-depth INT Max raw per-file depth; avoids excessive memory usage [%d]\n", mplp->max_depth); fprintf(fp, " -E, --redo-BAQ Recalculate BAQ on the fly, ignore existing BQs\n" " -f, --fasta-ref FILE Faidx indexed reference sequence file\n" " --no-reference Do not require fasta reference file\n" " -G, --read-groups FILE Select or exclude read groups listed in the file\n" " -q, --min-MQ INT Skip alignments with mapQ smaller than INT [%d]\n", mplp->min_mq); fprintf(fp, " -Q, --min-BQ INT Skip bases with baseQ/BAQ smaller than INT [%d]\n", mplp->min_baseQ); fprintf(fp, " --max-BQ INT Limit baseQ/BAQ to no more than INT [%d]\n", mplp->max_baseQ); fprintf(fp, " --delta-BQ INT Use neighbour_qual + INT if less than qual [%d]\n", mplp->delta_baseQ); fprintf(fp, " -r, --regions REG[,...] Comma separated list of regions in which pileup is generated\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --ignore-RG Ignore RG tags (one BAM = one sample)\n" " --ls, --skip-all-set STR|INT Skip reads with all of the bits set []\n"); fprintf(fp, " --ns, --skip-any-set STR|INT Skip reads with any of the bits set [%s]\n", tmp_skip_any_set); fprintf(fp, " --lu, --skip-all-unset STR|INT Skip reads with all of the bits unset []\n" " --nu, --skip-any-unset STR|INT Skip reads with any of the bits unset []\n"); fprintf(fp, " -s, --samples LIST Comma separated list of samples to include\n" " -S, --samples-file FILE File of samples to include\n" " -t, --targets REG[,...] Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " -x, --ignore-overlaps Disable read-pair overlap detection\n" " --seed INT Random number seed used for sampling deep regions [0]\n" "\n" "Output options:\n" " -a, --annotate LIST Optional tags to output; '\\?' to list available tags []\n" " -g, --gvcf INT[,...] Group non-variant sites into gVCF blocks according\n" " To minimum per-sample DP\n" " --no-version Do not append version and command line to the header\n" " -o, --output FILE Write output to FILE [standard output]\n" " -O, --output-type TYPE 'b' compressed BCF; 'u' uncompressed BCF;\n" " 'z' compressed VCF; 'v' uncompressed VCF; 0-9 compression level [v]\n" " --threads INT Use multithreading with INT worker threads [0]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "SNP/INDEL genotype likelihoods options:\n" " -X, --config STR Specify platform profile (use \"-X list\" for details)\n" " -e, --ext-prob INT Phred-scaled gap extension seq error probability [%d]\n", mplp->extQ); fprintf(fp, " -F, --gap-frac FLOAT Minimum fraction of gapped reads [%g]\n", mplp->min_frac); fprintf(fp, " -h, --tandem-qual INT Coefficient for homopolymer errors [%d]\n", mplp->tandemQ); fprintf(fp, " -I, --skip-indels Do not perform indel calling\n" " -L, --max-idepth INT Maximum per-file depth for INDEL calling [%d]\n", mplp->max_indel_depth); fprintf(fp, " -m, --min-ireads INT Minimum number gapped reads for indel candidates [%d]\n", mplp->min_support); fprintf(fp, " -M, --max-read-len INT Maximum length of read to pass to BAQ algorithm [%d]\n", mplp->max_read_len); fprintf(fp, " -o, --open-prob INT Phred-scaled gap open seq error probability [%d]\n", mplp->openQ); fprintf(fp, " -p, --per-sample-mF Apply -m and -F per-sample for increased sensitivity\n" " -P, --platforms STR Comma separated list of platforms for indels [all]\n" " --ar, --ambig-reads STR What to do with ambiguous indel reads: drop,incAD,incAD0 [drop]\n"); fprintf(fp, " --indel-bias FLOAT Raise to favour recall over precision [%.2f]\n", mplp->indel_bias); fprintf(fp, " --del-bias FLOAT Relative likelihood of insertion to deletion [%.2f]\n", mplp->del_bias); fprintf(fp, " --score-vs-ref FLOAT\n" " Ratio of score vs ref (1) or 2nd-best allele (0) [%.2f]\n", mplp->vs_ref); fprintf(fp, " --indel-size INT Approximate maximum indel size considered [%d]\n", mplp->indel_win_size); fprintf(fp, " --indels-2.0 New EXPERIMENTAL indel calling model (diploid reference consensus)\n" " --indels-cns New EXPERIMENTAL indel calling model with edlib\n" " --seqq-offset Indel-cns tuning for indel seq-qual scores [120]\n" " --no-indels-cns Disable CNS mode, to use after a -X profile\n" " --poly-mqual (Edlib mode) Use minimum quality within homopolymers\n"); fprintf(fp,"\n"); fprintf(fp, "Notes: Assuming diploid individuals.\n\n" "Example:\n" " # See also http://samtools.github.io/bcftools/howtos/variant-calling.html\n" " bcftools mpileup -Ou -f reference.fa alignments.bam | bcftools call -mv -Ob -o calls.bcf\n" "\n"); free(tmp_skip_all_set); free(tmp_skip_any_unset); free(tmp_skip_all_unset); free(tmp_skip_any_set); } static void print_profiles(void) { printf( "Configuration profiles activated with -X, --config:\n\n" "1.12\n" " -Q13 -h100 -m1 -F0.002\n\n" "bgi, bgi-1.20\n" " --indels-cns -B --indel-size 80 -F0.1 --indel-bias 0.9 --seqq-offset 120\n\n" "illumina-1.18\n" " --indel-size 110\n\n" "illumina\n" "illumina-1.20\n" " --indels-cns --indel-size 110\n\n" "ont\n" " -B -Q5 --max-BQ 30 -I\n\n" "ont-sup, ont-sup-1.20\n" " --indels-cns -B -Q1 --max-BQ 35 -F0.2 -o15 -e1 -h110 --delta-BQ 99\\\n" " --del-bias 0.4 --indel-bias 0.7 --poly-mqual --seqq-offset 130\\\n" " --indel-size 80\n\n" "pacbio-ccs-1.18\n" " -D -Q5 --max-BQ 50 -F0.1 -o25 -e1 --delta-BQ 10 \\\n" " -M99999 --indel-size 110\n\n" "pacbio-ccs, pacbio-ccs-1.20\n" " --indels-cns -B -Q5 --max-BQ 50 -F0.1 -o25 -e1 -h300 --delta-BQ 10 \\\n" " --del-bias 0.4 --poly-mqual --indel-bias 0.9 --seqq-offset 118\\\n" " --indel-size 80 --score-vs-ref 0.7\n\n" "ultima, ultima-1.20\n" " --indels-cns -B -Q1 --max-BQ 30 -F0.15 -o20 -e10 -h250 --delta-BQ 10 \\\n" " --del-bias 0.3 --indel-bias 0.7 --poly-mqual --seqq-offset 140 \\\n" " --indel-size 80 --score-vs-ref 0.3\n\n" "\n"); } int main_mpileup(int argc, char *argv[]) { int c, i, ret = 1; const char *file_list = NULL; char **fn = NULL; int nfiles = 0, use_orphan = 0, noref = 0; mplp_conf_t mplp; memset(&mplp, 0, sizeof(mplp_conf_t)); mplp.min_baseQ = 1; mplp.max_baseQ = 60; mplp.delta_baseQ = 30; mplp.capQ_thres = 0; mplp.max_depth = 250; mplp.max_indel_depth = 250; mplp.openQ = 40; mplp.extQ = 20; mplp.tandemQ = 500; mplp.min_frac = 0.05; mplp.indel_bias = 1.0; mplp.min_support = 2; mplp.vs_ref = 0; mplp.flag = MPLP_NO_ORPHAN | MPLP_REALN | MPLP_REALN_PARTIAL | MPLP_SMART_OVERLAPS; mplp.argc = argc; mplp.argv = argv; mplp.rflag_skip_any_set = BAM_FUNMAP | BAM_FSECONDARY | BAM_FQCFAIL | BAM_FDUP; mplp.output_fname = NULL; mplp.output_type = FT_VCF; mplp.record_cmd_line = 1; mplp.n_threads = 0; mplp.bsmpl = bam_smpl_init(); // the default to be changed in future, see also parse_format_flag() mplp.fmt_flag = B2B_INFO_BQBZ|B2B_INFO_IDV|B2B_INFO_IMF|B2B_INFO_MQ0F|B2B_INFO_MQBZ|B2B_INFO_MQSBZ|B2B_INFO_RPBZ|B2B_INFO_SCBZ|B2B_INFO_SGB|B2B_INFO_VDB|B2B_FMT_AD; mplp.max_read_len = 500; mplp.ambig_reads = B2B_DROP; mplp.indel_win_size = 110; mplp.poly_mqual = 0; mplp.seqQ_offset = 120; mplp.clevel = -1; mplp.del_bias = 0; // even insertion and deletion likelhoods. hts_srand48(0); static const struct option lopts[] = { {"nu", required_argument, NULL, 16}, {"lu", required_argument, NULL, 17}, {"rf", required_argument, NULL, 17}, // old --rf, --incl-flags = --lu, --skip-all-unset {"ns", required_argument, NULL, 18}, {"ff", required_argument, NULL, 18}, // old --ff, --excl-flags = --ns, --skip-any-set {"ls", required_argument, NULL, 19}, {"skip-any-unset", required_argument, NULL, 16}, {"skip-all-unset", required_argument, NULL, 17}, {"skip-any-set", required_argument, NULL, 18}, {"skip-all-set", required_argument, NULL, 19}, {"output", required_argument, NULL, 3}, {"open-prob", required_argument, NULL, 4}, {"ignore-RG", no_argument, NULL, 5}, {"ignore-rg", no_argument, NULL, 5}, {"gvcf", required_argument, NULL, 'g'}, {"no-reference", no_argument, NULL, 7}, {"no-version", no_argument, NULL, 8}, {"threads",required_argument,NULL,9}, {"illumina1.3+", no_argument, NULL, '6'}, {"count-orphans", no_argument, NULL, 'A'}, {"bam-list", required_argument, NULL, 'b'}, {"no-BAQ", no_argument, NULL, 'B'}, {"no-baq", no_argument, NULL, 'B'}, {"full-BAQ", no_argument, NULL, 'D'}, {"full-baq", no_argument, NULL, 'D'}, {"adjust-MQ", required_argument, NULL, 'C'}, {"adjust-mq", required_argument, NULL, 'C'}, {"max-depth", required_argument, NULL, 'd'}, {"redo-BAQ", no_argument, NULL, 'E'}, {"redo-baq", no_argument, NULL, 'E'}, {"fasta-ref", required_argument, NULL, 'f'}, {"read-groups", required_argument, NULL, 'G'}, {"region", required_argument, NULL, 'r'}, {"regions", required_argument, NULL, 'r'}, {"regions-file", required_argument, NULL, 'R'}, {"targets", required_argument, NULL, 't'}, {"targets-file", required_argument, NULL, 'T'}, {"min-MQ", required_argument, NULL, 'q'}, {"min-mq", required_argument, NULL, 'q'}, {"min-BQ", required_argument, NULL, 'Q'}, {"min-bq", required_argument, NULL, 'Q'}, {"max-bq", required_argument, NULL, 11}, {"max-BQ", required_argument, NULL, 11}, {"delta-BQ", required_argument, NULL, 12}, {"ignore-overlaps", no_argument, NULL, 'x'}, {"output-type", required_argument, NULL, 'O'}, {"samples", required_argument, NULL, 's'}, {"samples-file", required_argument, NULL, 'S'}, {"annotate", required_argument, NULL, 'a'}, {"ext-prob", required_argument, NULL, 'e'}, {"gap-frac", required_argument, NULL, 'F'}, {"indel-bias", required_argument, NULL, 10}, {"indel-size", required_argument, NULL, 15}, {"indels-2.0", no_argument, NULL, 20}, {"indels-cns", no_argument, NULL, 22}, {"no-indels-cns", no_argument, NULL, 25}, {"tandem-qual", required_argument, NULL, 'h'}, {"skip-indels", no_argument, NULL, 'I'}, {"max-idepth", required_argument, NULL, 'L'}, {"min-ireads", required_argument, NULL, 'm'}, {"per-sample-mF", no_argument, NULL, 'p'}, {"per-sample-mf", no_argument, NULL, 'p'}, {"platforms", required_argument, NULL, 'P'}, {"max-read-len", required_argument, NULL, 'M'}, {"config", required_argument, NULL, 'X'}, {"seed", required_argument, NULL, 13}, {"ambig-reads", required_argument, NULL, 14}, {"ar", required_argument, NULL, 14}, {"write-index",optional_argument,NULL,'W'}, {"del-bias", required_argument, NULL, 23}, {"poly-mqual", no_argument, NULL, 24}, {"no-poly-mqual", no_argument, NULL, 26}, {"score-vs-ref",required_argument, NULL, 27}, {"seqq-offset", required_argument, NULL, 28}, {NULL, 0, NULL, 0} }; while ((c = getopt_long(argc, argv, "Ag:f:r:R:q:Q:C:BDd:L:b:P:po:e:h:Im:F:EG:6O:xa:s:S:t:T:M:X:UW::",lopts,NULL)) >= 0) { switch (c) { case 'x': mplp.flag &= ~MPLP_SMART_OVERLAPS; break; case 16 : mplp.rflag_skip_any_unset = bam_str2flag(optarg); if ( mplp.rflag_skip_any_unset <0 ) { fprintf(stderr,"Could not parse --nf %s\n", optarg); goto err; } break; case 17 : mplp.rflag_skip_all_unset = bam_str2flag(optarg); if ( mplp.rflag_skip_all_unset<0 ) { fprintf(stderr,"Could not parse --if %s\n", optarg); goto err; } break; case 18 : mplp.rflag_skip_any_set = bam_str2flag(optarg); if ( mplp.rflag_skip_any_set <0 ) { fprintf(stderr,"Could not parse --ef %s\n", optarg); goto err; } break; case 19 : mplp.rflag_skip_all_set = bam_str2flag(optarg); if ( mplp.rflag_skip_all_set <0 ) { fprintf(stderr,"Could not parse --df %s\n", optarg); goto err; } break; case 3 : mplp.output_fname = optarg; break; case 4 : mplp.openQ = atoi(optarg); break; case 5 : bam_smpl_ignore_readgroups(mplp.bsmpl); break; case 'g': mplp.gvcf = gvcf_init(optarg); if ( !mplp.gvcf ) error("Could not parse: --gvcf %s\n", optarg); break; case 'f': mplp.fai = fai_load(optarg); if (mplp.fai == NULL) goto err; mplp.fai_fname = optarg; break; case 7 : noref = 1; break; case 8 : mplp.record_cmd_line = 0; break; case 9 : mplp.n_threads = strtol(optarg, 0, 0); break; case 'd': mplp.max_depth = atoi(optarg); break; case 'r': mplp.reg_fname = strdup(optarg); break; case 'R': mplp.reg_fname = strdup(optarg); mplp.reg_is_file = 1; break; case 't': // In the original version the whole BAM was streamed which is inefficient // with few BED intervals and big BAMs. Todo: devise a heuristic to determine // best strategy, that is streaming or jumping. if ( optarg[0]=='^' ) optarg++; else mplp.bed_logic = 1; mplp.bed = regidx_init(NULL,regidx_parse_reg,NULL,0,NULL); mplp.bed_itr = regitr_init(mplp.bed); if ( regidx_insert_list(mplp.bed,optarg,',') !=0 ) { fprintf(stderr,"Could not parse the targets: %s\n", optarg); exit(EXIT_FAILURE); } break; case 'T': if ( optarg[0]=='^' ) optarg++; else mplp.bed_logic = 1; mplp.bed = regidx_init(optarg,NULL,NULL,0,NULL); if (!mplp.bed) { fprintf(stderr, "bcftools mpileup: Could not read file \"%s\"", optarg); goto err; } break; case 'P': mplp.pl_list = strdup(optarg); break; case 'p': mplp.flag |= MPLP_PER_SAMPLE; break; case 'B': mplp.flag &= ~MPLP_REALN; break; case 'D': mplp.flag &= ~MPLP_REALN_PARTIAL; break; case 'I': mplp.flag |= MPLP_NO_INDEL; break; case 'E': mplp.flag |= MPLP_REDO_BAQ; break; case '6': mplp.flag |= MPLP_ILLUMINA13; break; case 's': if ( bam_smpl_add_samples(mplp.bsmpl,optarg,0)<0 ) error("Could not read samples: %s\n",optarg); break; case 'S': if ( bam_smpl_add_samples(mplp.bsmpl,optarg,1)<0 ) error("Could not read samples: %s\n",optarg); break; case 'O': switch (optarg[0]) { case 'b': mplp.output_type = FT_BCF_GZ; break; case 'u': mplp.output_type = FT_BCF; break; case 'z': mplp.output_type = FT_VCF_GZ; break; case 'v': mplp.output_type = FT_VCF; break; default: { char *tmp; mplp.clevel = strtol(optarg,&tmp,10); if ( *tmp || mplp.clevel<0 || mplp.clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { char *tmp; mplp.clevel = strtol(optarg+1,&tmp,10); if ( *tmp || mplp.clevel<0 || mplp.clevel>9 ) error("Could not parse argument: --output-type %s\n", optarg+1); } break; case 'C': mplp.capQ_thres = atoi(optarg); break; case 'q': mplp.min_mq = atoi(optarg); break; case 'Q': mplp.min_baseQ = atoi(optarg); break; case 11: mplp.max_baseQ = atoi(optarg); break; case 12: mplp.delta_baseQ = atoi(optarg); break; case 'b': file_list = optarg; break; case 'o': { char *end; long value = strtol(optarg, &end, 10); // Distinguish between -o INT and -o FILE (a bit of a hack!) if (*end == '\0') mplp.openQ = value; else mplp.output_fname = optarg; } break; case 'e': mplp.extQ = atoi(optarg); break; case 'h': mplp.tandemQ = atoi(optarg); break; case 10: // --indel-bias (inverted so higher => more indels called) if (atof(optarg) < 1e-2) mplp.indel_bias = 1/1e2; else mplp.indel_bias = 1/atof(optarg); break; case 27: mplp.vs_ref = atof(optarg); //if (mplp.vs_ref < 0) mplp.vs_ref = 0; if (mplp.vs_ref > 1) mplp.vs_ref = 1; break; case 15: { char *tmp; mplp.indel_win_size = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --indel-size %s\n", optarg); if ( mplp.indel_win_size < 20 ) { mplp.indel_win_size = 20; fprintf(stderr,"Warning: running with --indel-size %d, the requested value is too small\n",mplp.indel_win_size); } } break; case 20: mplp.indels_v20 = 1; mplp.edlib = 0; break; case 'W': if (!(mplp.write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 22: mplp.edlib = 1; mplp.indels_v20 = 0; break; case 25: mplp.edlib = 0; break; case 28: mplp.seqQ_offset = atoi(optarg); if (mplp.seqQ_offset < 100) mplp.seqQ_offset = 100; if (mplp.seqQ_offset > 200) mplp.seqQ_offset = 200; break; case 23: mplp.del_bias = atof(optarg); break; case 24: mplp.poly_mqual = 1; break; case 26: mplp.poly_mqual = 0; break; case 'A': use_orphan = 1; break; case 'F': mplp.min_frac = atof(optarg); break; case 'm': mplp.min_support = atoi(optarg); break; case 'L': mplp.max_indel_depth = atoi(optarg); break; case 'G': bam_smpl_add_readgroups(mplp.bsmpl, optarg, 1); break; case 'a': if (optarg[0]=='?') { list_annotations(stderr); goto err; } parse_format_flag(&mplp.fmt_flag,optarg); break; case 'M': mplp.max_read_len = atoi(optarg); break; case 'X': if (strcasecmp(optarg, "pacbio-ccs-1.18") == 0) { mplp.min_frac = 0.1; mplp.min_baseQ = 5; mplp.max_baseQ = 50; mplp.delta_baseQ = 10; mplp.openQ = 25; mplp.extQ = 1; mplp.flag |= MPLP_REALN_PARTIAL; mplp.max_read_len = 99999; } else if (strcasecmp(optarg, "pacbio-ccs") == 0 || strcasecmp(optarg, "pacbio-ccs-1.20") == 0) { mplp.min_frac = 0.1; mplp.min_baseQ = 5; mplp.max_baseQ = 50; mplp.delta_baseQ = 10; mplp.tandemQ = 300; mplp.openQ = 25; mplp.extQ = 1; mplp.flag &= ~MPLP_REALN; mplp.del_bias = 0.4; mplp.indel_bias = 1/.9; mplp.seqQ_offset = 118; mplp.poly_mqual = 1; mplp.edlib = 1; mplp.vs_ref = 0.7; mplp.indel_win_size = 80; } else if (strcasecmp(optarg, "ont") == 0) { fprintf(stderr, "With old ONT data may be beneficial to also run bcftools call with " "a higher -P, eg -P0.01 or -P 0.1\n"); mplp.min_baseQ = 5; mplp.max_baseQ = 30; mplp.flag &= ~MPLP_REALN; mplp.flag |= MPLP_NO_INDEL; } else if (strcasecmp(optarg, "ont-sup") == 0 || strcasecmp(optarg, "ont-sup-1.20") == 0) { mplp.min_frac = 0.2; mplp.min_baseQ = 1; mplp.max_baseQ = 35; mplp.delta_baseQ = 99; mplp.openQ = 15; mplp.extQ = 1; mplp.flag &= ~MPLP_REALN; mplp.max_read_len = 9999999; mplp.del_bias = 0.4; mplp.poly_mqual = 1; mplp.edlib = 1; // If we increase -h then we can increase bias denominator too mplp.tandemQ = 110; mplp.indel_bias = 1/0.7; mplp.seqQ_offset = 130; mplp.indel_win_size = 80; } else if (strcasecmp(optarg, "ultima") == 0 || strcasecmp(optarg, "ultima-1.20") == 0) { mplp.min_frac = 0.15; mplp.min_baseQ = 1; mplp.max_baseQ = 30; mplp.delta_baseQ = 10; mplp.openQ = 20; mplp.extQ = 10; mplp.tandemQ = 250; mplp.flag &= ~MPLP_REALN; mplp.del_bias = 0.3; mplp.poly_mqual = 1; mplp.edlib = 1; mplp.indel_bias = 1/0.7; mplp.seqQ_offset = 140; mplp.vs_ref = 0.3; mplp.indel_win_size = 80; } else if (strcasecmp(optarg, "1.12") == 0) { // 1.12 and earlier mplp.min_frac = 0.002; mplp.min_support = 1; mplp.min_baseQ = 13; mplp.tandemQ = 100; mplp.flag &= ~MPLP_REALN_PARTIAL; mplp.flag |= MPLP_REALN; } else if (strcasecmp(optarg, "illumina-1.18") == 0) { mplp.indel_win_size = 110; mplp.flag |= MPLP_REALN_PARTIAL; } else if (strcasecmp(optarg, "illumina") == 0 || strcasecmp(optarg, "illumina-1.20") == 0) { mplp.edlib = 1; mplp.indel_win_size = 110; mplp.flag |= MPLP_REALN_PARTIAL; mplp.indel_bias = 1; mplp.seqQ_offset = 125; //mplp.indel_win_size = 80; TEST? } else if (strcasecmp(optarg, "bgi") == 0 || strcasecmp(optarg, "bgi-1.20") == 0) { mplp.min_frac = 0.1; mplp.edlib = 1; mplp.indel_bias = 1; mplp.seqQ_offset = 120; mplp.flag |= MPLP_REALN_PARTIAL; mplp.indel_win_size = 80; } else if (strcasecmp(optarg, "list") == 0 || strcasecmp(optarg, "help") == 0) { print_profiles(); goto err; } else { fprintf(stderr, "Unknown configuration name '%s'\n" "Please use '-X list' to show available choices.\n", optarg); goto err; } break; case 13: hts_srand48(atoi(optarg)); break; case 14: if ( !strcasecmp(optarg,"drop") ) mplp.ambig_reads = B2B_DROP; else if ( !strcasecmp(optarg,"incAD") ) mplp.ambig_reads = B2B_INC_AD; else if ( !strcasecmp(optarg,"incAD0") ) mplp.ambig_reads = B2B_INC_AD0; else error("The option to --ambig-reads not recognised: %s\n",optarg); break; default: fprintf(stderr,"Invalid option: '%c'\n", c); goto err; } } if ( mplp.gvcf && !(mplp.fmt_flag&B2B_FMT_DP) ) { fprintf(stderr,"[warning] The -a DP option is required with --gvcf, switching on.\n"); mplp.fmt_flag |= B2B_FMT_DP; } if ( mplp.flag&(MPLP_BCF|MPLP_VCF|MPLP_NO_COMP) ) { if ( mplp.flag&MPLP_VCF ) { if ( mplp.flag&MPLP_NO_COMP ) mplp.output_type = FT_VCF; else mplp.output_type = FT_VCF_GZ; } else if ( mplp.flag&MPLP_BCF ) { if ( mplp.flag&MPLP_NO_COMP ) mplp.output_type = FT_BCF; else mplp.output_type = FT_BCF_GZ; } } if ( !(mplp.flag&MPLP_REALN) && mplp.flag&MPLP_REDO_BAQ ) { fprintf(stderr,"Error: The -B option cannot be combined with -E\n"); goto err; } if (use_orphan) mplp.flag &= ~MPLP_NO_ORPHAN; if (argc == 1) { print_usage(stderr, &mplp); goto err; } if (!mplp.fai && !noref) { fprintf(stderr,"Error: mpileup requires the --fasta-ref option by default; use --no-reference to run without a fasta reference\n"); goto err; } if (file_list) { if ( read_file_list(file_list,&nfiles,&fn) ) goto err; mplp.files = fn; mplp.nfiles = nfiles; } else { mplp.nfiles = argc - optind; mplp.files = (char**) malloc(mplp.nfiles*sizeof(char*)); for (i=0; i 0003.vcf.gz; tabix -f 0003.vcf.gz; bgzip < 0000.vcf > 0000.vcf.gz; tabix -f 0000.vcf.gz; bgzip < 0001.vcf > 0001.vcf.gz;tabix -f 0001.vcf.gz) d=_new/bcftools.isec (cd $d; bgzip < 0003.vcf > 0003.vcf.gz; tabix -f 0003.vcf.gz; bgzip < 0000.vcf > 0000.vcf.gz; tabix -f 0000.vcf.gz; bgzip < 0001.vcf > 0001.vcf.gz;tabix -f 0001.vcf.gz) # Produce a new isec output bcftools isec -p _fp _{old,new}/0001.vcf.gz _{old,new}/0001.vcf is the false positives our two runs produces. After intersecting those, we now have: - _fp/0000.vcf: old false positives we have removed - _fp/0001.vcf: new false positives we have acquired Similarly on _{old,new}/0000.vcf to identify cured / caused false-negatives. This provides a way to data mine things much more carefully. We can further drill down on these cured/caused variants by subdividing into deletions vs insertions, or filtering to high quality only. ----------------------------------------------------------------------------- There is also run_multi.sh which can call 3 samples together (eg a trio), splits them, and then checks the calling works per sample when in the presence of other samples. This also produces PNG files. Note the above script requires a working bcftools plugins system. This won't be in your path by default if building from a source tree, so you may need to manually set BCFTOOLS_PLUGINS=$srcdir/plugins first. For example: BENCHDIR=$bcftools_src/mpileup_bench \ BCFTOOLS=$bcftools_src/bcftools \ $bcftools_src/mpileup_bench/run_multi.sh \ HG00[234].illumima.bam illumina.out -X illumina See the gnuplot example script at the end for ideas on how to merge multiple runs together to visualise the impact of a change. E.g. "devel" vs a local modification. bcftools-1.21/mpileup_bench/compare_vcf_simple.sh000077500000000000000000000352711467060157400223000ustar00rootroot00000000000000#!/bin/bash # # Usage compare_vcf A.vcf B.vcf [region-skip.bed] bcftools=${BCFTOOLS:-bcftools} vt=${VT:-/nfs/users/nfs_j/jkb/lustre/vt/vt} if [ $# -lt 2 ] then echo Usage: compare_vcf A.vcf B.vcf [region-skip.bed] [region-include.bed] [region] exit 1 fi v1=$1 v2=$2 exclude=$3 include=$4 region=$5 qual=${QUAL:-30} #href=${HREF:-/nfs/srpipe_references/references/Human/1000Genomes_hs37d5/all/fasta/hs37d5.fa} href=${REF:-$HREF38} pp() { awk "END {printf(\"%f\", 100 *$1 / $2)}" < /dev/null } norm() { # Also consider norm "-m +both" without a "-d both" step. # This produces more differences, but is also more correct. v=$1 if [ x"$region" != x ] then #$bcftools norm -t $region -f $href $v 2>/dev/null | $bcftools norm -d both -N | $bcftools view -T ^$exclude | $bcftools view -T $include > $v.norm.vcf #$bcftools norm -m -both -t $region -f $href $v 2>/dev/null | $bcftools view -T ^$exclude | $bcftools view -T $include > $v.norm.vcf if [ x"$exclude" != x ] then $bcftools norm -m -both -t $region -f $href $v 2>/dev/null | $vt decompose_blocksub - 2>/dev/null | $bcftools view -T ^$exclude | $bcftools view -T $include > $v.norm.vcf else $bcftools norm -m -both -t $region -f $href $v 2>/dev/null | $vt decompose_blocksub - 2>/dev/null | $bcftools view -T $include > $v.norm.vcf fi elif [ x"$include" != x ] then $bcftools norm -m -both -f $href $v 2>/dev/null | $vt decompose_blocksub - 2>/dev/null | $bcftools view -T ^$exclude | $bcftools view -T $include > $v.norm.vcf elif [ x"$exclude" != x ] then $bcftools norm -m -both -f $href $v 2>/dev/null | $vt decompose_blocksub - 2>/dev/null | $bcftools view -T ^$exclude > $v.norm.vcf else $bcftools norm -m -both -f $href $v 2>/dev/null | $vt decompose_blocksub - 2>/dev/null > $v.norm.vcf fi rm $v.norm.vcf.gz 2>/dev/null bgzip $v.norm.vcf $bcftools index $v.norm.vcf.gz } if [ "$NORM" != "" ] then norm $v1 fi norm $v2 # NB: consider CHM13_1 chr20:2241427 # The Illumina data is all mapped with high mqual and shows homozygous deletion # of AAAC in an AAAC STR. The truth set claims AAAC del is heterozygous. # # $Bcftools isec therefore claims it is shared between both sets (in 0002 and 0003.vcf) # but also only in the query set (0001) due to the extra allele. #$bcftools isec -p $v1.isec $v1.norm.vcf.gz $v2.norm.vcf.gz $bcftools isec -c both -p $v2.isec $v1.norm.vcf.gz $v2.norm.vcf.gz # Or "-c any"? Works better possibly # 0000 is private to v1 => FN # 0001 is private to v2 => FP # 0002/3 are records common to v1/v2 (from v1 or v2 respectively => TP) # Depth filtering is beneficial to all tools, so we use it in this evaluation. case $v2 in *15x*) dp=15;DP=30;; *30x*) dp=30;DP=60;; *53X*) dp=53;DP=106;; *60x*) dp=60;DP=120;; *100x*) dp=100;DP=200;; *150x*) dp=150;DP=300;; *300x*) dp=300;DP=600;; *) dp=90;DP=120;; # *) DP=90;; esac case $v2 in *gatk*) prog=GATK #gatk: https://software.broadinstitute.org/gatk/documentation/article.php?id=3225 # s_filt_exp="QUAL < $qual || QD < 2 || FS > 60 || MQ < 40 || SOR > 3 || MQRankSum < -12.5 || ReadPosRankSum < -8" # i_filt_exp="QUAL < $qual || QD < 2 || FS > 200 || ReadPosRankSum < -20" s_filt_exp="QUAL < $qual || QD < 2 || FS > 60 || MQ < 40 || SOR > 3 || MQRankSum < -2.5 || ReadPosRankSum < -8 || INFO/DP>$DP" i_filt_exp="QUAL < $qual || QD < 2 || FS > 60 || ReadPosRankSum < -8 || INFO/DP>$DP || SOR > 3" # better on GIAB. Also on others? Unknown. SOR 3->6 and MQ 40->20 s_filt_exp="QUAL < $qual || QD < 2 || FS > 60 || MQ < 20 || SOR > 6 || MQRankSum < -4 || ReadPosRankSum < -8 || INFO/DP>$DP" # Depth aware variant of above s_filt_exp="QUAL < $qual || QD < 2 || FS > 55+INFO/DP/6 || MQ < 20 || SOR > 6+INFO/DP/25 || MQRankSum < -(3+INFO/DP/50) || ReadPosRankSum < -(3.5+INFO/DP/50) || INFO/DP>$DP" ;; *freebayes*) prog=Freebayes #freebayes: https://wiki.uiowa.edu/download/attachments/145192256/erik%20garrison%20-%20iowa%20talk%202.pdf?api=v2 #s_filt_exp="QUAL < $qual || SAF <= 0 || SAR <= 0 || RPR <= 1 || RPL <= 1 || INFO/DP > $DP" s_filt_exp="QUAL < $qual || SAF <= 0 || SAR <= 0 || RPR <= 0 || RPL <= 0 || INFO/DP > $DP" #i_filt_exp=$s_filt_exp #i_filt_exp="QUAL < $qual || INFO/DP > $DP" i_filt_exp="QUAL < $qual || RPR <= 0 || RPL <= 0 || INFO/DP > $DP" ;; *bcftools*) prog=Bcftools # Simple filters; QUAL, DP and for indels IDV/IMF s_filt_exp="QUAL < $qual || DP>$DP" i_filt_exp="IDV < 3 || IMF < 0.1 || DP>$DP || QUAL < $qual" # Suggest: #s_filt_exp="QUAL < $qual || DP>$dp*2 || MQBZ < -(4+$dp/30) || RPBZ > (3.5+$dp/60) || RPBZ < -(3.5+$dp/60) || FORMAT/SP > 30+$dp/2 || SCBZ > 3+$dp/50" #q_filt_exp="IDV<(2+DP*$qual/2000) || IMF < 0.02+(($qual+1)/($qual+31))*(($qual+1)/($qual+31))/3 || DP>$dp*2 || MQBZ < -(4+$dp/30) || FORMAT/SP > 30+$dp/2 || RPBZ+SCBZ > 5.5" # I_FILT_EXP='IDV<(2+DP*$qual/2000) || IMF < 0.02+(($qual+1)/($qual+31))*(($qual+1)/($qual+31))/3 || DP>$dp*2 || MQBZ < -(4+$dp/30) || FORMAT/SP > 30+$dp/2 || RPBZ+SCBZ > 5.5' S_FILT_EXP='QUAL < $qual || DP>$dp*2 || MQBZ < -(4+$dp/30) || RPBZ > (3.5+$dp/60) || RPBZ < -(3.5+$dp/60) || FORMAT/SP > 30+$dp/2 || SCBZ > 3+$dp/50' ./compare_vcf_simple.sh ;; *octopus*) prog=octopus s_filt_exp="FILTER!=\"PASS\" || QUAL < $qual || INFO/DP>$DP" i_filt_exp="FILTER!=\"PASS\" || QUAL < $qual || INFO/DP>$DP" ;; *) prog=Unknown echo Unrecognised type, no specific filters s_filt_exp="QUAL<$qual || INFO/DP>$DP" i_filt_exp="QUAL<$qual || INFO/DP>$DP" ;; esac S_FILT_EXP=`eval echo \"${S_FILT_EXP:-$s_filt_exp}\"` I_FILT_EXP=`eval echo \"${I_FILT_EXP:-$i_filt_exp}\"` #echo "SNP: $S_FILT_EXP" 1>&2 #echo "Indel: $I_FILT_EXP" 1>&2 # We classify wrong genotypes as both a true and untrue call. We don't # label it as a false negative as the call exists and it's not as bad # a situation as missing it entirely. # Hacky addition of GTFAIL filter if 0002.vcf and 0003.vcf have a different # GT call. perl -e 'BEGIN {$"="\t"} open(F1,"<'$v2'.isec/0002.vcf");open(F2,"<'$v2'.isec/0003.vcf");$_=;print;print "##FILTER=\n";while() {next if /^#/;chomp($_);@F=split("\t",$_);$F[-1]=~/^(\d+)[|\/](\d+)/;$gt=($1<$2)?"$1/$2":"$2/$1";while () {if (/^#/) {print;next} else {last}};chomp($_);@G=split("\t",$_);$G[-1]=~/^(\d+)[|\/](\d+)/;$gt2=($1<$2)?"$1/$2":"$2/$1";if ($gt ne $gt2) {$G[6]="GTFAIL"} print "@G\n"}' > $v2.isec/0003b.vcf # Produce isec/filtered.vcf as a filtered copy of the call set, so # we can pass this to rtg vcfeval for an alternative way of evaluating # data sets. $bcftools view -e "QUAL < $qual || (TYPE='snp' && ($S_FILT_EXP)) || (TYPE='indel' && ($I_FILT_EXP))" $v2 > $v2.isec/filtered.vcf # QUAL 1 is recommended minimum for freebayes to remove detritus. v1_snp=` $bcftools view -H -i "TYPE='snp'" $v2.isec/0000.vcf|wc -l` v2_snp=` $bcftools view -H -i "TYPE='snp' && QUAL >= 1" $v2.isec/0001.vcf|wc -l` v2_snp_hq=` $bcftools view -H -i "TYPE='snp' && QUAL >= $qual" $v2.isec/0001.vcf|wc -l` v2_snp_fi=` $bcftools view -i "TYPE='snp'" $v2.isec/0001.vcf | bcftools view -H -e "$S_FILT_EXP" -|wc -l` v12_snp=` $bcftools view -H -i "TYPE='snp'" $v2.isec/0002.vcf|wc -l` v12_snp_hq=`$bcftools view -H -i "TYPE='snp' && QUAL >= $qual" $v2.isec/0003.vcf|wc -l` v12_snp_fi=`$bcftools view -i "TYPE='snp'" $v2.isec/0003.vcf | bcftools view -H -e "$S_FILT_EXP" -|wc -l` v12_snp_gt=` $bcftools view -H -f GTFAIL -i "TYPE='snp' && QUAL >= 1" $v2.isec/0003b.vcf|wc -l` v12_snp_hq_gt=`$bcftools view -H -f GTFAIL -i "TYPE='snp' && QUAL >= $qual" $v2.isec/0003b.vcf|wc -l` v12_snp_fi_gt=`$bcftools view -f GTFAIL -i "TYPE='snp'" $v2.isec/0003b.vcf | bcftools view -H -e "$I_FILT_EXP" -|wc -l` #v2_snp=`expr $v2_snp + $v12_snp_gt` #v2_snp_hq=`expr $v2_snp_hq + $v12_snp_hq_gt` #v2_snp_fi=`expr $v2_snp_fi + $v12_snp_fi_gt` v1_indel=` $bcftools view -H -i "TYPE='indel'" $v2.isec/0000.vcf|wc -l` v2_indel=` $bcftools view -H -i "TYPE='indel' && QUAL >= 1" $v2.isec/0001.vcf|wc -l` v2_indel_hq=` $bcftools view -H -i "TYPE='indel' && QUAL >= $qual" $v2.isec/0001.vcf|wc -l` v2_indel_fi=` $bcftools view -i "TYPE='indel'" $v2.isec/0001.vcf | bcftools view -H -e "$I_FILT_EXP" -|wc -l` v12_indel=` $bcftools view -H -i "TYPE='indel'" $v2.isec/0002.vcf|wc -l` v12_indel_hq=`$bcftools view -H -i "TYPE='indel' && QUAL >= $qual" $v2.isec/0003.vcf|wc -l` v12_indel_fi=`$bcftools view -i "TYPE='indel'" $v2.isec/0003.vcf | bcftools view -H -e "$I_FILT_EXP" -|wc -l` v12_indel_gt=` $bcftools view -H -f GTFAIL -i "TYPE='indel'" $v2.isec/0003b.vcf|wc -l` v12_indel_hq_gt=`$bcftools view -H -f GTFAIL -i "TYPE='indel' && QUAL >= $qual" $v2.isec/0003b.vcf|wc -l` v12_indel_fi_gt=`$bcftools view -f GTFAIL -i "TYPE='indel'" $v2.isec/0003b.vcf | bcftools view -H -e "$I_FILT_EXP" -|wc -l` #v2_indel=`expr $v2_indel + $v12_indel_gt` #v2_indel_hq=`expr $v2_indel_hq + $v12_indel_hq_gt` #v2_indel_fi=`expr $v2_indel_fi + $v12_indel_fi_gt` # quality trimmed FN aren't the records private to v1 above QUAL, but the # total number of records not in v12 after filtering. Thus as we increase # acceptance threshold to reduce FP we increase FN. v1_snp_hq=`expr $v1_snp + $v12_snp - $v12_snp_hq` v1_snp_fi=`expr $v1_snp + $v12_snp - $v12_snp_fi` v1_indel_hq=`expr $v1_indel + $v12_indel - $v12_indel_hq` v1_indel_fi=`expr $v1_indel + $v12_indel - $v12_indel_fi` # Assumption A.vcf is truth set and B.vcf is test set if [ "$FORMAT" = "tex" ] then printf '\\bigskip\n' printf '\\begin{minipage}{\\linewidth}\n' printf '\\centering\n' printf '\\captionof{table}{%s: FIXME}\n' $prog printf '{\\begin{tabular}{ll|r|rr}\n' printf 'Variants & & \\textbf{Q>0} & \\textbf{Q>=%d} & \\textbf{Filtered} \\\\ \\midrule\n' $qual printf 'SNP & TP & %7d & %7d & %7d \\\\\n' $v12_snp $v12_snp_hq $v12_snp_fi printf 'SNP & FP & %7d & %7d & %7d \\\\\n' $v2_snp $v2_snp_hq $v2_snp_fi printf 'SNP & GT & %7d & %7d & %7d \\\\\n' $v12_snp_gt $v12_snp_hq_gt $v12_snp_fi_gt printf 'SNP & FN & %7d & %7d & %7d \\\\\n' $v1_snp $v1_snp_hq $v1_snp_fi printf '\\midrule\n'; printf 'InDel & TP & %7d & %7d & %7d \\\\\n' $v12_indel $v12_indel_hq $v12_indel_fi printf 'InDel & FP & %7d & %7d & %7d \\\\\n' $v2_indel $v2_indel_hq $v2_indel_fi printf 'InDel & GT & %7d & %7d & %7d \\\\\n' $v12_indel_gt $v12_indel_hq_gt $v12_indel_fi_gt printf 'InDel & FN & %7d & %7d & %7d \\\\\n' $v1_indel $v1_indel_hq $v1_indel_fi printf '\\end{tabular}}\n' printf '\\par\n' printf '\\textbf{CRAM qual size x,x}\n' printf '\\bigskip\n' printf '\\end{minipage}\n' elif [ "$FORMAT" = "gnuplot" ] then # v1_snp = total number of FN SNPs (at any qual; from truth set) # v2_snp = total number of FP SNPs (at any qual; our extra calls) # v12_snp = total number of TP SNPs # => v12_snp + v1_snp = total true SNPs # # Columns: # Filename # Qual $q # No. TP SNP in this 10-qual bin # No. FP SNP in this 10-qual bin # No. TP Indel in this 10-qual bin # No. FP Indel in this 10-qual bin # Total no. SNPs # Number FN SNP at QUAL >= $q # Number FP SNP at QUAL >= $q # Total no. INDELs # Number FN INDEL at QUAL >= $q # Number FP INDEL at QUAL >= $q # //Number GT SNP errs at QUAL >= $q tot_snp=`expr $v1_snp + $v12_snp` tot_indel=`expr $v1_indel + $v12_indel` # For gnuplot for Q in `seq 0 10 250` do qual=$Q qual_max=`expr $Q + 10` v2_snp_hq=` $bcftools view -H -i "TYPE='snp' && QUAL >= $qual && QUAL < $qual_max" $v2.isec/0001.vcf|wc -l` v2_snp_hq2=` $bcftools view -H -i "TYPE='snp' && QUAL >= $qual" $v2.isec/0001.vcf|wc -l` v12_snp_hq=`$bcftools view -H -i "TYPE='snp' && QUAL >= $qual && QUAL < $qual_max" $v2.isec/0003.vcf|wc -l` v12_snp_hq2=`$bcftools view -H -i "TYPE='snp' && QUAL >= $qual" $v2.isec/0003.vcf|wc -l` v2_indel_hq=` $bcftools view -H -i "TYPE='indel' && QUAL >= $qual && QUAL < $qual_max" $v2.isec/0001.vcf|wc -l` v2_indel_hq2=` $bcftools view -H -i "TYPE='indel' && QUAL >= $qual" $v2.isec/0001.vcf|wc -l` v12_indel_hq=`$bcftools view -H -i "TYPE='indel' && QUAL >= $qual && QUAL < $qual_max" $v2.isec/0003.vcf|wc -l` v12_indel_hq2=`$bcftools view -H -i "TYPE='indel' && QUAL >= $qual" $v2.isec/0003.vcf|wc -l` # Total number of SNPs minus true HQ snps we call v12_snp_hq2=`expr $tot_snp - $v12_snp_hq2` v12_indel_hq2=`expr $tot_indel - $v12_indel_hq2` printf "$v2\t$qual\t$v12_snp_hq $v2_snp_hq\t$v12_indel_hq $v2_indel_hq\t$tot_snp $v12_snp_hq2 $v2_snp_hq2\t$tot_indel $v12_indel_hq2 $v2_indel_hq2\n" done elif [ "$FORMAT" = "percent" ] then printf "SNP Q>0 / Q>=$qual / Filtered\n" x=`expr $v12_snp + $v1_snp` printf "SNP TP %7.2f / %7.2f / %7.2f\n" \ `pp $v12_snp $x` `pp $v12_snp_hq $x` `pp $v12_snp_fi $x` x=`expr $v12_snp + $v2_snp` printf "SNP FP %7.2f / %7.2f / %7.2f\n" \ `pp $v2_snp $x` `pp $v2_snp_hq $x` `pp $v2_snp_fi $x` x=`expr $v12_snp` printf 'SNP GT %7.2f / %7.2f / %7.2f\n' \ `pp $v12_snp_gt $x` `pp $v12_snp_hq_gt $x` `pp $v12_snp_fi_gt $x` x=`expr $v12_snp + $v1_snp` printf "SNP FN %7.2f / %7.2f / %7.2f\n" \ `pp $v1_snp $x` `pp $v1_snp_hq $x` `pp $v1_snp_fi $x` #printf "SNP %4.1f%% prec, %4.1f%% rec\n" 100.0*$v12_snp_hq/($v12_snp_hq+$v2_snp_hq) 100.0*$v12_snp_hq/($v12_snp_hq+$v1_snp_hq); printf "\n"; x=`expr $v12_indel + $v1_indel` printf "InDel TP %7.2f / %7.2f / %7.2f\n" \ `pp $v12_indel $x` `pp $v12_indel_hq $x` `pp $v12_indel_fi $x` x=`expr $v12_indel + $v2_indel` printf "InDel FP %7.2f / %7.2f / %7.2f\n" \ `pp $v2_indel $x` `pp $v2_indel_hq $x` `pp $v2_indel_fi $x` x=`expr $v12_indel` printf 'InDel GT %7.2f / %7.2f / %7.2f\n' \ `pp $v12_indel_gt $x` `pp $v12_indel_hq_gt $x` `pp $v12_indel_fi_gt $x` x=`expr $v12_indel + $v1_indel` printf "InDel FN %7.2f / %7.2f / %7.2f\n" \ `pp $v1_indel $x` `pp $v1_indel_hq $x` `pp $v1_indel_fi $x` else printf "SNP Q>0 / Q>=$qual / Filtered\n" printf "SNP TP %7d / %7d / %7d\n" $v12_snp $v12_snp_hq $v12_snp_fi printf "SNP FP %7d / %7d / %7d\n" $v2_snp $v2_snp_hq $v2_snp_fi printf 'SNP GT %7d / %7d / %7d\n' $v12_snp_gt $v12_snp_hq_gt $v12_snp_fi_gt printf "SNP FN %7d / %7d / %7d\n" $v1_snp $v1_snp_hq $v1_snp_fi #printf "SNP %4.1f%% prec, %4.1f%% rec\n" 100.0*$v12_snp_hq/($v12_snp_hq+$v2_snp_hq) 100.0*$v12_snp_hq/($v12_snp_hq+$v1_snp_hq); printf "\n"; printf "InDel TP %7d / %7d / %7d\n" $v12_indel $v12_indel_hq $v12_indel_fi printf "InDel FP %7d / %7d / %7d\n" $v2_indel $v2_indel_hq $v2_indel_fi printf 'InDel GT %7d / %7d / %7d\n' $v12_indel_gt $v12_indel_hq_gt $v12_indel_fi_gt printf "InDel FN %7d / %7d / %7d\n" $v1_indel $v1_indel_hq $v1_indel_fi #printf "InDel %4.1f%% prec, %4.1f%% rec\n" 100.0*$v12_indel_hq/($v12_indel_hq+$v2_indel_hq) 100.0*$v12_indel_hq/($v12_indel_hq+$v1_indel_hq); fi #rm $v1.norm* $v2.norm* #rm -rf $v2.isec bcftools-1.21/mpileup_bench/get_data.sh000077500000000000000000000064271467060157400202140ustar00rootroot00000000000000# ---------------------------------------------------------------------- # Human reference # I have this locally: # /nfs/srpipe_references/references/Human/GRCh38_full_analysis_set_plus_decoy_hla/all/fasta/Homo_sapiens.GRCh38_full_analysis_set_plus_decoy_hla.fa # This has 3366 sequences. # The BAMs appear to be aligned against 2580 sequences. # The GIAB reference directory appears to be a few hundred max. # I'm unsure where their reference used was, but if we stick to the # already aligned files and stick to the primary chromosomes then # frankly any GRCh38 should be fine for evaluation purposes. # (NB: unsure if true for chr21 due to changes, but that may be in # patch form only) # ---------------------------------------------------------------------- # HG005 for final evaluation only # chr20 only # ---- Truth set echo "Fetching truth set" wget https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/ChineseTrio/HG005_NA24631_son/NISTv4.2.1/GRCh38/HG005_GRCh38_1_22_v4.2.1_benchmark.bed wget https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/ChineseTrio/HG005_NA24631_son/NISTv4.2.1/GRCh38/HG005_GRCh38_1_22_v4.2.1_benchmark.vcf.gz wget https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/ChineseTrio/HG005_NA24631_son/NISTv4.2.1/GRCh38/HG005_GRCh38_1_22_v4.2.1_benchmark.vcf.gz.tbi # ---- Data files reg=chr20:20000000-21000000 echo "Getting Illumina $reg" samtools view -o illumina_300x.bam --write-index -@8 https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/data/ChineseTrio/HG005_NA24631_son/HG005_NA24631_son_HiSeq_300x/NHGRI_Illumina300X_Chinesetrio_novoalign_bams/HG005.GRCh38_full_plus_hs38d1_analysis_set_minus_alts.300x.bam $reg echo "Getting PacBio $reg" samtools view -o pacbio_50x.bam --write-index -@8 https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/data/ChineseTrio/HG005_NA24631_son/NIST_BGIseq_2x150bp_100x/GRCh38/HG005_GRCh38_BGIseq-2x150-100x_NIST_20211126.bam $reg echo "Getting BGI $reg" samtools view -o bgi_100x.bam --write-index -@8 https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/data/ChineseTrio/HG005_NA24631_son/PacBio_CCS_15kb_20kb_chemistry2/GRCh38/GIAB_5mC_CpG/HG005.GRCh38.deepvariant.haplotagged.bam $reg # ---------------------------------------------------------------------- # HG002 for code modification, tuning, tweaking and round-trips. # chr1 only # ---- Truth set echo "Fetching truth set" wget https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/AshkenazimTrio/HG002_NA24385_son/NISTv4.2.1/GRCh38/HG002_GRCh38_1_22_v4.2.1_benchmark.vcf.gz wget https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/AshkenazimTrio/HG002_NA24385_son/NISTv4.2.1/GRCh38/HG002_GRCh38_1_22_v4.2.1_benchmark.vcf.gz.tbi wget https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/AshkenazimTrio/HG002_NA24385_son/NISTv4.2.1/GRCh38/HG002_GRCh38_1_22_v4.2.1_benchmark.noinconsistent.bed # ---- Data files # Data is same locations as above, but more data available. Have a browse # basically and decide what to test with reg=chr1 echo "Browse https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/data/AshkenazimTrio/HG002_NA24385_son/" # eg https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/data/AshkenazimTrio/HG002_NA24385_son/Element_AVITI_20231018/HG002_GRCh37_Element-StdInsert_2X150_81x_20231018.bam bcftools-1.21/mpileup_bench/plot_isec.pl000077500000000000000000000107771467060157400204310ustar00rootroot00000000000000#!/usr/bin/perl -w # Reports the cumulative total of false positives, genotype assignment errors, # and false negatives. These are using an assumed filter of QUAL>=x, so as we # increase QUAL filtering we're removing errors (FP and GT) and increasing # missing calls (FN). # # We also report these in percentage terms. # FP is fraction of called variants that are false # GT is fraction of true variants with the wrong genotype # FN is fraction of true variants not called use strict; my $dir=shift(@ARGV); my $type=shift(@ARGV); my ($fn_count, $I_fn_count, $D_fn_count) = (0,0,0); my ($fp_count, $I_fp_count, $D_fp_count) = (0,0,0); my ($gt_count, $I_gt_count, $D_gt_count) = (0,0,0); my (@fp, @I_fp, @D_fp); my (@tp, @I_tp, @D_tp); my (@gt, @I_gt, @D_gt); my ($total_true, $I_total_true, $D_total_true) = (0,0,0); # False negatives. No score, so just count them as base number open(my $fn, "bcftools query -i 'TYPE=\"$type\"' -f '%QUAL %REF %ALT\n' $dir/0000.vcf|"); while (<$fn>) { my ($q,$r,$a) = split(/\s+/,$_); $fn_count++; $I_fn_count++ if (length($r) < length($a)); $D_fn_count++ if (length($r) > length($a)); } close($fn); # False positives, bin by QUAL open(my $fp, "bcftools query -i 'TYPE=\"$type\"' -f '%QUAL %REF %ALT\n' $dir/0001.vcf|"); while (<$fp>) { my ($q,$r,$a) = split(/\s+/,$_); @fp[int($q)]++; $fp_count++; if (length($r) < length($a)) { @I_fp[int($q)]++; $I_fp_count++; } if (length($r) > length($a)) { @D_fp[int($q)]++; $D_fp_count++; } } close($fp); # True positives, bin by QUAL my $total_tp_call = 0; my $I_total_tp_call = 0; my $D_total_tp_call = 0; open(my $tp, "bcftools query -i 'TYPE=\"$type\"' -f '%QUAL %REF %ALT %FILTER\n' $dir/0003b.vcf|"); while (<$tp>) { my ($q,$r,$a,$f) = split(/\s+/,$_); $total_tp_call++; @tp[int($q)]++; if (length($r) < length($a)) { $I_total_tp_call++; @I_tp[int($q)]++; } if (length($r) > length($a)) { $D_total_tp_call++; @D_tp[int($q)]++; } if (/GTFAIL/) { @gt[int($q)]++; $gt_count++; if (length($r) < length($a)) { @I_gt[int($q)]++; $I_gt_count++; } if (length($r) > length($a)) { @D_gt[int($q)]++; $D_gt_count++; } } } close($tp); $total_true = $fn_count + $total_tp_call; $I_total_true = $I_fn_count + $I_total_tp_call; $D_total_true = $D_fn_count + $D_total_tp_call; print STDERR "Total true indel: $total_true\n"; print STDERR "Total true ins: $I_total_true\n"; print STDERR "Total true del:: $D_total_true\n"; print STDERR " QUAL : FP GT FN\n"; for (my $qual = 0; $qual < 5000; $qual++) { $fp_count -= $fp[$qual] if (defined($fp[$qual])); $fn_count += $tp[$qual] if (defined($tp[$qual])); $gt_count -= $gt[$qual] if (defined($gt[$qual])); last if $fp_count == 0; $I_fp_count -= $I_fp[$qual] if (defined($I_fp[$qual])); $I_fn_count += $I_tp[$qual] if (defined($I_tp[$qual])); $I_gt_count -= $I_gt[$qual] if (defined($I_gt[$qual])); $D_fp_count -= $D_fp[$qual] if (defined($D_fp[$qual])); $D_fn_count += $D_tp[$qual] if (defined($D_tp[$qual])); $D_gt_count -= $D_gt[$qual] if (defined($D_gt[$qual])); my $total_call = $total_true - $fn_count + $fp_count; my $I_total_call = $I_total_true - $I_fn_count + $I_fp_count; my $D_total_call = $D_total_true - $D_fn_count + $D_fp_count; printf("ALL %4d : %5d %5d %5d", $qual, $fp_count, $gt_count, $fn_count); printf(" : %7.4f %7.4f %7.4f $total_call\n", 100*$fp_count/$total_call, 100*$gt_count/$total_true, 100*$fn_count/$total_true); printf("INS %4d : %5d %5d %5d", $qual, $I_fp_count, $I_gt_count, $I_fn_count); printf(" : %7.4f %7.4f %7.4f\n", 100*$I_fp_count/$I_total_call, 100*$I_gt_count/$I_total_true, 100*$I_fn_count/$I_total_true); printf("DEL %4d : %5d %5d %5d", $qual, $D_fp_count, $D_gt_count, $D_fn_count); printf(" : %7.4f %7.4f %7.4f\n", 100*$D_fp_count/$D_total_call, 100*$D_gt_count/$D_total_true, 100*$D_fn_count/$D_total_true); } __END__ /nfs/users/nfs_j/jkb/work/samtools_master/bcftools/plot_isec.pl HG002.GRCh38.60x.RG.bcftools-10h.vcf.isec indel > _2 Total true indel: 45604 Total true ins: 22194 Total true del:: 23410 # Plot FP (x) vs FN (y) a=8;b=10;plot "$dir/bcftools.mpileup.out | $bcftools call -vm - > $dir/bcftools.vcf 2>$dir/bcftools.call.out # A primary evaluation. # They key thing here is it leaves behind the .isec directory with the # intersection of the truth and call sets. echo "=== ./compare_vcf_simple.sh $TRUTH $dir/bcftools.vcf "" $BED $region" QUAL=30 NORM=1 ./compare_vcf_simple.sh $TRUTH $dir/bcftools.vcf "" $BED $region # Produce a .plot file for use in gnuplot, along with a basic summary too. echo "=== ./plot_isec.pl $dir/bcftools.vcf.isec indel > $dir/plot++" ./plot_isec.pl $dir/bcftools.vcf.isec indel > $dir/plot++ grep ALL $dir/plot++ > $dir/plot grep INS $dir/plot++ > $dir/plot.ins grep DEL $dir/plot++ > $dir/plot.del awk 'BEGIN {n=0} $6 >= n {print;n=50*(1+int($6/50))}' $dir/plot | cut -c 1-28|head -20 # Example gnuplot: # set xlabel "FPr" # set ylabel "FNr" # set yrange [0:10] # set title "PacBio 50x indels" # FP vs FN # a=8;b=10;t="ALL";plot "$dir/bcftools.mpileup.out | $bcftools call -vm - > $dir/bcftools.vcf 2>$dir/bcftools.call.out # Split into the input samples echo echo "===; $bcftools +split $dir/bcftools.vcf -o $dir" eval $bcftools +split $dir/bcftools.vcf -o $dir set -- `$bcftools view -h $dir/bcftools.vcf|tail -1|cut -f 10-` vcf2=$1.vcf vcf3=$2.vcf vcf4=$3.vcf # Remove non-sample data echo echo "===; $bcftools norm -m -both -f $HREF38 $dir/$vcf2 | grep -v '[.0]/[.0]:' > $dir/_$vcf2" eval $bcftools norm -m -both -f $HREF38 $dir/$vcf2 | grep -v '[.0]/[.0]:' > $dir/_$vcf2 echo "===; $bcftools norm -m -both -f $HREF38 $dir/$vcf3 | grep -v '[.0]/[.0]:' > $dir/_$vcf3" eval $bcftools norm -m -both -f $HREF38 $dir/$vcf3 | grep -v '[.0]/[.0]:' > $dir/_$vcf3 echo "===; $bcftools norm -m -both -f $HREF38 $dir/$vcf4 | grep -v '[.0]/[.0]:' > $dir/_$vcf4" eval $bcftools norm -m -both -f $HREF38 $dir/$vcf4 | grep -v '[.0]/[.0]:' > $dir/_$vcf4 # A primary evaluation. # They key thing here is it leaves behind the .isec directory with the # intersection of the truth and call sets. echo echo "===; QUAL=30 NORM=1 ${BENCHDIR}/compare_vcf_simple.sh $TRUTH002 $dir/_$vcf2 '' $BED002 $region" QUAL=30 NORM=1 ${BENCHDIR}/compare_vcf_simple.sh $TRUTH002 $dir/_$vcf2 "" $BED002 $region echo "===; QUAL=30 NORM=1 ${BENCHDIR}/compare_vcf_simple.sh $TRUTH003 $dir/_$vcf3 '' $BED003 $region" QUAL=30 NORM=1 ${BENCHDIR}/compare_vcf_simple.sh $TRUTH003 $dir/_$vcf3 "" $BED003 $region echo "===; QUAL=30 NORM=1 ${BENCHDIR}/compare_vcf_simple.sh $TRUTH004 $dir/_$vcf4 '' $BED004 $region" QUAL=30 NORM=1 ${BENCHDIR}/compare_vcf_simple.sh $TRUTH004 $dir/_$vcf4 "" $BED004 $region # Produce a .plot file for use in gnuplot, along with a basic summary too. echo "===; ${BENCHDIR}/plot_isec.pl $dir/_$vcf2.isec indel > $dir/2.all" ${BENCHDIR}/plot_isec.pl $dir/_$vcf2.isec indel > $dir/2.out grep ALL $dir/2.out > $dir/2.all grep INS $dir/2.out > $dir/2.ins grep DEL $dir/2.out > $dir/2.del awk 'BEGIN {n=0} $6 >= n {print;n=50*(1+int($6/50))}' $dir/2.all | cut -c 1-28|head -20 echo "===; ${BENCHDIR}/plot_isec.pl $dir/_$vcf3.isec indel > $dir/3.all" ${BENCHDIR}/plot_isec.pl $dir/_$vcf3.isec indel > $dir/3.out grep ALL $dir/3.out > $dir/3.all grep INS $dir/3.out > $dir/3.ins grep DEL $dir/3.out > $dir/3.del awk 'BEGIN {n=0} $6 >= n {print;n=50*(1+int($6/50))}' $dir/3.all | cut -c 1-28|head -20 echo "===; ${BENCHDIR}/plot_isec.pl $dir/_$vcf4.isec indel > $dir/4.all" ${BENCHDIR}/plot_isec.pl $dir/_$vcf4.isec indel > $dir/4.out grep ALL $dir/4.out > $dir/4.all grep INS $dir/4.out > $dir/4.ins grep DEL $dir/4.out > $dir/4.del awk 'BEGIN {n=0} $6 >= n {print;n=50*(1+int($6/50))}' $dir/4.all | cut -c 1-28|head -20 else # Short cut to replot results without rerunning the calling set -- `$bcftools view -h $dir/bcftools.vcf|tail -1|cut -f 10-` vcf2=$1.vcf vcf3=$2.vcf vcf4=$3.vcf fi # Generate GNU plots echo === Running gnuplot to create "HG00[234]*.png" gnuplot < Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ // Code to build this table is below #ifdef BUILD_MW #include double mann_whitney_1947(int n, int m, int U) { if (U<0) return 0; if (n==0||m==0) return U==0 ? 1 : 0; return (double)n/(n+m)*mann_whitney_1947(n-1,m,U-m) + (double)m/(n+m)*mann_whitney_1947(n,m-1,U); } int main(void) { int i, j, k; printf("static double mw[6][6][50] = // [2-7][2-7][0-49]\n{\n"); for (i = 2; i < 8; i++) { printf(" {\n"); for (j = 2; j < 8; j++) { printf(" {\n"); for (k = 0; k < 50; k++) { printf(" %.17f,\n", mann_whitney_1947(i,j,k)); } printf(" },\n"); } printf(" },\n"); } printf("};\n"); return 0; } #endif static double mw[6][6][50] = // [2-7][2-7][0-49] { { { 0.16666666666666666, 0.16666666666666666, 0.33333333333333331, 0.16666666666666666, 0.16666666666666666, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.09999999999999999, 0.09999999999999999, 0.19999999999999998, 0.20000000000000001, 0.20000000000000001, 0.10000000000000001, 0.10000000000000001, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.06666666666666665, 0.06666666666666665, 0.13333333333333330, 0.13333333333333333, 0.20000000000000001, 0.13333333333333333, 0.13333333333333333, 0.06666666666666667, 0.06666666666666667, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.04761904761904761, 0.04761904761904761, 0.09523809523809522, 0.09523809523809523, 0.14285714285714288, 0.14285714285714285, 0.14285714285714285, 0.09523809523809523, 0.09523809523809523, 0.04761904761904762, 0.04761904761904762, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.03571428571428571, 0.03571428571428571, 0.07142857142857141, 0.07142857142857142, 0.10714285714285715, 0.10714285714285714, 0.14285714285714285, 0.10714285714285715, 0.10714285714285715, 0.07142857142857144, 0.07142857142857142, 0.03571428571428571, 0.03571428571428571, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.02777777777777777, 0.02777777777777777, 0.05555555555555555, 0.05555555555555555, 0.08333333333333334, 0.08333333333333333, 0.11111111111111110, 0.11111111111111113, 0.11111111111111113, 0.08333333333333334, 0.08333333333333334, 0.05555555555555556, 0.05555555555555555, 0.02777777777777778, 0.02777777777777778, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, }, { { 0.10000000000000001, 0.10000000000000001, 0.20000000000000001, 0.20000000000000001, 0.19999999999999998, 0.09999999999999999, 0.09999999999999999, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.05000000000000000, 0.05000000000000000, 0.10000000000000001, 0.14999999999999999, 0.14999999999999999, 0.14999999999999999, 0.14999999999999999, 0.10000000000000001, 0.05000000000000000, 0.05000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.02857142857142857, 0.02857142857142857, 0.05714285714285714, 0.08571428571428570, 0.11428571428571427, 0.11428571428571427, 0.14285714285714282, 0.11428571428571428, 0.11428571428571428, 0.08571428571428572, 0.05714285714285714, 0.02857142857142857, 0.02857142857142857, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.01785714285714286, 0.01785714285714286, 0.03571428571428571, 0.05357142857142856, 0.07142857142857142, 0.08928571428571427, 0.10714285714285711, 0.10714285714285712, 0.10714285714285714, 0.10714285714285715, 0.08928571428571427, 0.07142857142857142, 0.05357142857142857, 0.03571428571428571, 0.01785714285714286, 0.01785714285714286, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.01190476190476190, 0.01190476190476190, 0.02380952380952381, 0.03571428571428571, 0.04761904761904762, 0.05952380952380951, 0.08333333333333330, 0.08333333333333331, 0.09523809523809523, 0.09523809523809523, 0.09523809523809523, 0.08333333333333333, 0.08333333333333333, 0.05952380952380952, 0.04761904761904762, 0.03571428571428571, 0.02380952380952381, 0.01190476190476190, 0.01190476190476190, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, 0.00000000000000000, }, { 0.00833333333333333, 0.00833333333333333, 0.01666666666666666, 0.02499999999999999, 0.03333333333333333, 0.04166666666666666, 0.05833333333333331, 0.06666666666666665, 0.07499999999999998, 0.08333333333333331, 0.08333333333333331, 0.08333333333333333, 0.08333333333333333, 0.07500000000000000, 0.06666666666666667, 0.05833333333333333, 0.04166666666666666, 0.03333333333333333, 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0.00757575757575758, 0.00582750582750583, 0.00437062937062937, 0.00320512820512821, 0.00203962703962704, 0.00145687645687646, 0.00087412587412587, 0.00058275058275058, 0.00029137529137529, 0.00029137529137529, }, }, }; bcftools-1.21/peakfit.c000066400000000000000000000431551467060157400150610ustar00rootroot00000000000000/* The MIT License Copyright (c) 2013-2015 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include "peakfit.h" #include #include #include #include #include #include #include #include #define NPARAMS 5 // gauss params: sqrt(scale), center, sigma typedef struct _peak_t { int fit_mask; double params[NPARAMS], ori_params[NPARAMS]; // current and input parameters struct { int scan; double min, max, best; } mc[NPARAMS]; // monte-carlo settings and best parameter void (*calc_f) (int nvals, double *xvals, double *yvals, void *args); void (*calc_df) (int nvals, double *xvals, double *yvals, double *dfvals, int idf, void *args); void (*print_func) (struct _peak_t *pk, kstring_t *str); void (*convert_get) (struct _peak_t *pk, double *params); double (*convert_set) (struct _peak_t *pk, int iparam, double value); } peak_t; struct _peakfit_t { int npeaks, mpeaks, nparams, mparams; peak_t *peaks; double *params; int nvals, mvals; double *xvals, *yvals, *vals; kstring_t str; int verbose, nmc_iter; }; /* Gaussian peak with the center bound in the interval : yi = scale^2 * exp(-(xi-z)^2/sigma^2) dy/dscale = 2*scale * EXP dy/dcenter = -scale^2 * sin(center) * (e-d) * (xi - z) * EXP / sigma^2 dy/dsigma = 2*scale^2 * (xi - z)^2 * EXP / sigma^3 where z = 0.5*(cos(center)+1)*(e-d) + d EXP = exp(-(xi-z)^2/sigma^2) */ void bounded_gaussian_calc_f(int nvals, double *xvals, double *yvals, void *args) { peak_t *pk = (peak_t*) args; double scale2 = pk->params[0] * pk->params[0]; double center = pk->params[1]; double sigma = pk->params[2]; double d = pk->params[3]; double e = pk->params[4]; double z = 0.5*(cos(center)+1)*(e-d) + d; int i; for (i=0; iparams[0]; double center = pk->params[1]; double sigma = pk->params[2]; double d = pk->params[3]; double e = pk->params[4]; double z = 0.5*(cos(center)+1)*(e-d) + d; int i; for (i=0; iparams[1]; double d = pk->params[3]; double e = pk->params[4]; double z = 0.5*(cos(center)+1)*(e-d) + d; ksprintf(str,"%f**2 * exp(-(x-%f)**2/%f**2)",fabs(pk->params[0]),z,fabs(pk->params[2])); } double bounded_gaussian_convert_set(peak_t *pk, int iparam, double value) { if ( iparam!=1 ) return value; double d = pk->ori_params[3]; double e = pk->ori_params[4]; if ( valuee ) value = e; return acos(2*(value-d)/(e-d) - 1); } void bounded_gaussian_convert_get(peak_t *pk, double *params) { params[0] = fabs(pk->params[0]); params[2] = fabs(pk->params[2]); double center = pk->params[1]; double d = pk->params[3]; double e = pk->params[4]; params[1] = 0.5*(cos(center)+1)*(e-d) + d; } void peakfit_add_bounded_gaussian(peakfit_t *pkf, double a, double b, double c, double d, double e, int fit_mask) { pkf->npeaks++; hts_expand0(peak_t,pkf->npeaks,pkf->mpeaks,pkf->peaks); int i, nfit = 0; for (i=0; inparams += nfit; hts_expand0(double,pkf->nparams,pkf->mparams,pkf->params); peak_t *pk = &pkf->peaks[pkf->npeaks-1]; memset(pk, 0, sizeof(peak_t)); pk->calc_f = bounded_gaussian_calc_f; pk->calc_df = bounded_gaussian_calc_df; pk->print_func = bounded_gaussian_sprint_func; pk->convert_set = bounded_gaussian_convert_set; pk->convert_get = bounded_gaussian_convert_get; pk->fit_mask = fit_mask; pk->ori_params[0] = a; pk->ori_params[2] = c; pk->ori_params[3] = d; pk->ori_params[4] = e; pk->ori_params[1] = pk->convert_set(pk, 1, b); } /* Gaussian peak: yi = scale^2 * exp(-(x-center)^2/sigma^2) dy/dscale = 2 * scale * EXP dy/dcenter = 2 * scale^2 * (x-center) * EXP / sigma^2 dy/dsigma = 2 * scale^2 * (x-center)^2 * EXP / sigma^3 where EXP = exp(-(x-center)^2/sigma^2) */ void gaussian_calc_f(int nvals, double *xvals, double *yvals, void *args) { peak_t *pk = (peak_t*) args; double scale2 = pk->params[0] * pk->params[0]; double center = pk->params[1]; double sigma = pk->params[2]; int i; for (i=0; iparams[0]; double center = pk->params[1]; double sigma = pk->params[2]; int i; for (i=0; iparams[0]),pk->params[1],fabs(pk->params[2])); } void gaussian_convert_get(peak_t *pk, double *params) { params[0] = fabs(pk->params[0]); params[1] = fabs(pk->params[1]); params[2] = fabs(pk->params[2]); } void peakfit_add_gaussian(peakfit_t *pkf, double a, double b, double c, int fit_mask) { pkf->npeaks++; hts_expand0(peak_t,pkf->npeaks,pkf->mpeaks,pkf->peaks); int i, nfit = 0; for (i=0; inparams += nfit; hts_expand0(double,pkf->nparams,pkf->mparams,pkf->params); peak_t *pk = &pkf->peaks[pkf->npeaks-1]; memset(pk, 0, sizeof(peak_t)); pk->calc_f = gaussian_calc_f; pk->calc_df = gaussian_calc_df; pk->print_func = gaussian_sprint_func; pk->convert_get = gaussian_convert_get; pk->fit_mask = fit_mask; pk->ori_params[0] = a; pk->ori_params[1] = b; pk->ori_params[2] = c; } /* exp peak: yi = scale^2 * exp((x-center)/sigma^2) dy/dscale = 2 * scale * EXP dy/dcenter = -scale^2 * EXP / sigma^2 dy/dsigma = -2 * scale^2 * (x-center) * EXP / sigma^3 where EXP = exp((x-center)/sigma^2) */ void exp_calc_f(int nvals, double *xvals, double *yvals, void *args) { peak_t *pk = (peak_t*) args; double scale2 = pk->params[0] * pk->params[0]; double center = pk->params[1]; double sigma = pk->params[2]; int i; for (i=0; iparams[0]; double center = pk->params[1]; double sigma = pk->params[2]; int i; for (i=0; iparams[0]),pk->params[1],fabs(pk->params[2])); } void exp_convert_get(peak_t *pk, double *params) { params[0] = fabs(pk->params[0]); params[1] = fabs(pk->params[1]); params[2] = fabs(pk->params[2]); } void peakfit_add_exp(peakfit_t *pkf, double a, double b, double c, int fit_mask) { pkf->npeaks++; hts_expand0(peak_t,pkf->npeaks,pkf->mpeaks,pkf->peaks); int i, nfit = 0; for (i=0; inparams += nfit; hts_expand0(double,pkf->nparams,pkf->mparams,pkf->params); peak_t *pk = &pkf->peaks[pkf->npeaks-1]; memset(pk, 0, sizeof(peak_t)); pk->calc_f = exp_calc_f; pk->calc_df = exp_calc_df; pk->print_func = exp_sprint_func; pk->convert_get = exp_convert_get; pk->fit_mask = fit_mask; pk->ori_params[0] = a; pk->ori_params[1] = b; pk->ori_params[2] = c; } void peakfit_set_params(peakfit_t *pkf, int ipk, double *params, int nparams) { peak_t *pk = &pkf->peaks[ipk]; int i; if ( pk->convert_set ) for (i=0; iparams[i] = pk->convert_set(pk, i, params[i]); else for (i=0; iparams[i] = params[i]; } void peakfit_get_params(peakfit_t *pkf, int ipk, double *params, int nparams) { peak_t *pk = &pkf->peaks[ipk]; if ( pk->convert_get ) pk->convert_get(pk, params); else { int i; for (i=0; iparams[i]; } } peakfit_t *peakfit_init(void) { return (peakfit_t*)calloc(1,sizeof(peakfit_t)); } void peakfit_reset(peakfit_t *pkf) { pkf->npeaks = pkf->nparams = 0; memset(pkf->peaks,0,sizeof(peak_t)*pkf->mpeaks); } void peakfit_destroy(peakfit_t *pkf) { free(pkf->str.s); free(pkf->vals); free(pkf->params); free(pkf->peaks); free(pkf); } int peakfit_calc_f(const gsl_vector *params, void *data, gsl_vector *yvals) { peakfit_t *pkf = (peakfit_t *) data; int i,j; for (i=0; invals; i++) pkf->vals[i] = 0; int iparam = 0; for (i=0; inpeaks; i++) { peak_t *pk = &pkf->peaks[i]; for (j=0; jfit_mask & (1<params[j] = gsl_vector_get(params,iparam); iparam++; } pk->calc_f(pkf->nvals, pkf->xvals, pkf->vals, pk); } for (i=0; invals; i++) gsl_vector_set(yvals, i, (pkf->vals[i] - pkf->yvals[i])/0.01); return GSL_SUCCESS; } int peakfit_calc_df(const gsl_vector *params, void *data, gsl_matrix *jacobian) { peakfit_t *pkf = (peakfit_t *) data; int i,j,k,iparam = 0; for (i=0; inpeaks; i++) { peak_t *pk = &pkf->peaks[i]; int iparam_prev = iparam; for (j=0; jfit_mask & (1<params[j] = gsl_vector_get(params,iparam); iparam++; } iparam = iparam_prev; for (j=0; jfit_mask & (1<nvals; k++) pkf->vals[k] = 0; pk->calc_df(pkf->nvals, pkf->xvals, pkf->yvals, pkf->vals, j, pk); for (k=0; knvals; k++) gsl_matrix_set(jacobian, k, iparam, pkf->vals[k]); iparam++; } } return GSL_SUCCESS; } int peakfit_calc_fdf(const gsl_vector *params, void *data, gsl_vector *yvals, gsl_matrix *jacobian) { peakfit_calc_f(params, data, yvals); peakfit_calc_df(params, data, jacobian); return GSL_SUCCESS; } double peakfit_evaluate(peakfit_t *pkf) { int i; for (i=0; invals; i++) pkf->vals[i] = 0; for (i=0; inpeaks; i++) pkf->peaks[i].calc_f(pkf->nvals, pkf->xvals, pkf->vals, &pkf->peaks[i]); double sum = 0; for (i=0; invals; i++) sum += fabs(pkf->vals[i] - pkf->yvals[i]); return sum; } const char *peakfit_sprint_func(peakfit_t *pkf) { pkf->str.l = 0; int i; for (i=0; inpeaks; i++) { if ( i>0 ) kputs(" + ", &pkf->str); pkf->peaks[i].print_func(&pkf->peaks[i], &pkf->str); } return (const char*)pkf->str.s; } void peakfit_verbose(peakfit_t *pkf, int level) { pkf->verbose = level; } void peakfit_set_mc(peakfit_t *pkf, double xmin, double xmax, int iparam, int niter) { peak_t *pk = &pkf->peaks[ pkf->npeaks-1 ]; pk->mc[iparam].scan = 1; pk->mc[iparam].min = xmin; pk->mc[iparam].max = xmax; pkf->nmc_iter = niter; } double peakfit_run(peakfit_t *pkf, int nvals, double *xvals, double *yvals) { srand(0); // for reproducibility pkf->nvals = nvals; pkf->xvals = xvals; pkf->yvals = yvals; hts_expand0(double,pkf->nvals,pkf->mvals,pkf->vals); if ( !pkf->nparams ) return peakfit_evaluate(pkf); gsl_multifit_function_fdf mfunc; mfunc.f = &peakfit_calc_f; mfunc.df = &peakfit_calc_df; mfunc.fdf = &peakfit_calc_fdf; mfunc.n = nvals; mfunc.p = pkf->nparams; mfunc.params = pkf; const gsl_multifit_fdfsolver_type *solver_type; gsl_multifit_fdfsolver *solver; solver_type = gsl_multifit_fdfsolver_lmsder; solver = gsl_multifit_fdfsolver_alloc(solver_type, nvals, mfunc.p); gsl_vector *grad = gsl_vector_alloc(pkf->nparams); int imc_iter, i,j, iparam; double best_fit = HUGE_VAL; for (imc_iter=0; imc_iter<=pkf->nmc_iter; imc_iter++) // possibly multiple monte-carlo iterations { // set GSL parameters iparam = 0; for (i=0; inpeaks; i++) { peak_t *pk = &pkf->peaks[i]; for (j=0; jparams[j] = pk->ori_params[j]; if ( pk->mc[j].scan ) { pk->params[j] = rand()*(pk->mc[j].max - pk->mc[j].min)/RAND_MAX + pk->mc[j].min; if ( pk->convert_set ) pk->params[j] = pk->convert_set(pk, j, pk->params[j]); } if ( !(pk->fit_mask & (1<params[iparam] = pk->params[j]; iparam++; } } gsl_vector_view vview = gsl_vector_view_array(pkf->params, mfunc.p); gsl_multifit_fdfsolver_set(solver, &mfunc, &vview.vector); // iterate until convergence (or lack of it) int ret, test1 = 0, test2 = 0, niter = 0, niter_max = 500; do { ret = gsl_multifit_fdfsolver_iterate(solver); if ( pkf->verbose >1 ) { fprintf(stderr, "%d: ", niter); for (i=0; inpeaks; i++) { peak_t *pk = &pkf->peaks[i]; fprintf(stderr,"\t%f %f %f", pk->params[0],pk->params[1],pk->params[2]); } fprintf(stderr, "\t.. %s\n", gsl_strerror(ret)); } if ( ret ) break; #if GSL_MAJOR_VERSION >= 2 int info; test1 = gsl_multifit_fdfsolver_test(solver, 1e-8,1e-8, 0.0, &info); #else gsl_multifit_gradient(solver->J, solver->f, grad); test1 = gsl_multifit_test_gradient(grad, 1e-8); test2 = gsl_multifit_test_delta(solver->dx, solver->x, 1e-8, 1e-8); #endif } while ((test1==GSL_CONTINUE || test2==GSL_CONTINUE) && ++niterverbose >1 ) { fprintf(stderr,"test1=%s\n", gsl_strerror(test1)); fprintf(stderr,"test2=%s\n", gsl_strerror(test2)); } // recover parameters iparam = 0; for (i=0; inpeaks; i++) { peak_t *pk = &pkf->peaks[i]; for (j=0; jfit_mask & (1<params[j] = gsl_vector_get(solver->x, iparam++); } } // evaluate fit, update best parameters double fit = peakfit_evaluate(pkf); if ( fitnpeaks; i++) { peak_t *pk = &pkf->peaks[i]; for (j=0; jmc[j].best = pk->params[j]; } } if ( fitnpeaks; i++) { peak_t *pk = &pkf->peaks[i]; for (j=0; jparams[j] = pk->mc[j].best; } return best_fit; } bcftools-1.21/peakfit.h000066400000000000000000000041231467060157400150560ustar00rootroot00000000000000/* The MIT License Copyright (c) 2013-2015 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef PEAKFIT_H #define PEAKFIT_H typedef struct _peakfit_t peakfit_t; peakfit_t *peakfit_init(void); void peakfit_reset(peakfit_t *pkf); void peakfit_destroy(peakfit_t *pkf); void peakfit_add_gaussian(peakfit_t *pkf, double a, double b, double c, int fit_mask); void peakfit_add_bounded_gaussian(peakfit_t *pkf, double a, double b, double c, double d, double e, int fit_mask); void peakfit_add_exp(peakfit_t *pkf, double a, double b, double c, int fit_mask); void peakfit_set_mc(peakfit_t *pkf, double xmin, double xmax, int iparam, int niter); double peakfit_run(peakfit_t *pkf, int nvals, double *xvals, double *yvals); double peakfit_evaluate(peakfit_t *pkf); void peakfit_verbose(peakfit_t *pkf, int level); void peakfit_get_params(peakfit_t *pkf, int ipk, double *params, int nparams); void peakfit_set_params(peakfit_t *pkf, int ipk, double *params, int nparams); const char *peakfit_sprint_func(peakfit_t *pkf); #endif bcftools-1.21/ploidy.c000066400000000000000000000177071467060157400147420ustar00rootroot00000000000000/* Copyright (C) 2014-2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include "bcftools.h" #include "ploidy.h" struct _ploidy_t { int nsex, msex; // number of genders, m:number of allocated elements in id2sex array int dflt, min, max; // ploidy: default, min and max (only explicitly listed) int *sex2dflt; regidx_t *idx; regitr_t *itr; void *sex2id; char **id2sex; kstring_t tmp_str; }; typedef struct { int sex, ploidy; } sex_ploidy_t; regidx_t *ploidy_regions(ploidy_t *ploidy) { return ploidy->idx; } int ploidy_parse(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { int i, ret; ploidy_t *ploidy = (ploidy_t*) usr; void *sex2id = ploidy->sex2id; // Check for special case of default ploidy "* * * " int default_ploidy_def = 0; char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( ss[0]=='*' && (!ss[1] || isspace(ss[1])) ) default_ploidy_def = 1; // definition of default ploidy, chr="*" else { // Fill CHR,FROM,TO ret = regidx_parse_tab(line,chr_beg,chr_end,beg,end,NULL,NULL); if ( ret!=0 ) return ret; } // Skip the fields already parsed by regidx_parse_tab ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; for (i=0; i<3; i++) { while ( *ss && !isspace(*ss) ) ss++; if ( !*ss ) return -2; // wrong number of fields while ( *ss && isspace(*ss) ) ss++; } if ( !*ss ) return -2; // Parse the payload char *se = ss; while ( *se && !isspace(*se) ) se++; if ( !*se || se==ss ) error("Could not parse: %s\n", line); ploidy->tmp_str.l = 0; kputsn(ss,se-ss,&ploidy->tmp_str); sex_ploidy_t *sp = (sex_ploidy_t*) payload; if ( khash_str2int_get(sex2id, ploidy->tmp_str.s, &sp->sex) != 0 ) { ploidy->nsex++; hts_expand0(char*,ploidy->nsex,ploidy->msex,ploidy->id2sex); ploidy->id2sex[ploidy->nsex-1] = strdup(ploidy->tmp_str.s); sp->sex = khash_str2int_inc(ploidy->sex2id, ploidy->id2sex[ploidy->nsex-1]); ploidy->sex2dflt = (int*) realloc(ploidy->sex2dflt,sizeof(int)*ploidy->nsex); ploidy->sex2dflt[ploidy->nsex-1] = -1; } ss = se; while ( *se && isspace(*se) ) se++; if ( !*se ) error("Could not parse: %s\n", line); sp->ploidy = strtol(ss,&se,10); if ( ss==se ) error("Could not parse: %s\n", line); if ( ploidy->min<0 || sp->ploidy < ploidy->min ) ploidy->min = sp->ploidy; if ( ploidy->max<0 || sp->ploidy > ploidy->max ) ploidy->max = sp->ploidy; // Special case, chr="*" stands for a default value if ( default_ploidy_def ) { ploidy->sex2dflt[ploidy->nsex-1] = sp->ploidy; return -1; } return 0; } static void _set_defaults(ploidy_t *ploidy, int dflt) { int i; if ( khash_str2int_get(ploidy->sex2id, "*", &i) == 0 ) dflt = ploidy->sex2dflt[i]; for (i=0; insex; i++) if ( ploidy->sex2dflt[i]==-1 ) ploidy->sex2dflt[i] = dflt; ploidy->dflt = dflt; if ( ploidy->min<0 || dflt < ploidy->min ) ploidy->min = dflt; if ( ploidy->max<0 || dflt > ploidy->max ) ploidy->max = dflt; } ploidy_t *ploidy_init(const char *fname, int dflt) { ploidy_t *pld = (ploidy_t*) calloc(1,sizeof(ploidy_t)); if ( !pld ) return NULL; pld->min = pld->max = -1; pld->sex2id = khash_str2int_init(); pld->idx = regidx_init(fname,ploidy_parse,NULL,sizeof(sex_ploidy_t),pld); if ( !pld->idx ) { ploidy_destroy(pld); return NULL; } pld->itr = regitr_init(pld->idx); _set_defaults(pld,dflt); return pld; } ploidy_t *ploidy_init_string(const char *str, int dflt) { ploidy_t *pld = (ploidy_t*) calloc(1,sizeof(ploidy_t)); if ( !pld ) return NULL; pld->min = pld->max = -1; pld->sex2id = khash_str2int_init(); pld->idx = regidx_init(NULL,ploidy_parse,NULL,sizeof(sex_ploidy_t),pld); pld->itr = regitr_init(pld->idx); kstring_t tmp = {0,0,0}; const char *ss = str; while ( *ss ) { while ( *ss && isspace(*ss) ) ss++; const char *se = ss; while ( *se && *se!='\r' && *se!='\n' ) se++; tmp.l = 0; kputsn(ss, se-ss, &tmp); regidx_insert(pld->idx,tmp.s); while ( *se && isspace(*se) ) se++; ss = se; } free(tmp.s); _set_defaults(pld,dflt); return pld; } void ploidy_destroy(ploidy_t *ploidy) { if ( ploidy->sex2id ) khash_str2int_destroy_free(ploidy->sex2id); if ( ploidy->itr ) regitr_destroy(ploidy->itr); if ( ploidy->idx ) regidx_destroy(ploidy->idx); free(ploidy->id2sex); free(ploidy->tmp_str.s); free(ploidy->sex2dflt); free(ploidy); } int ploidy_query(ploidy_t *ploidy, char *seq, int pos, int *sex2ploidy, int *min, int *max) { int i, ret = regidx_overlap(ploidy->idx, seq,pos,pos, ploidy->itr); if ( !sex2ploidy && !min && !max ) return ret; if ( !ret ) { // no overlap if ( min ) *min = ploidy->dflt; if ( max ) *max = ploidy->dflt; if ( sex2ploidy ) for (i=0; insex; i++) sex2ploidy[i] = ploidy->sex2dflt[i]; return 0; } int _min = INT_MAX, _max = -1; if ( sex2ploidy ) for (i=0; insex; i++) sex2ploidy[i] = ploidy->dflt; while ( regitr_overlap(ploidy->itr) ) { int sex = regitr_payload(ploidy->itr,sex_ploidy_t).sex; int pld = regitr_payload(ploidy->itr,sex_ploidy_t).ploidy; if ( pld!=ploidy->dflt ) { if ( sex2ploidy ) sex2ploidy[ sex ] = pld; if ( _min > pld ) _min = pld; if ( _max < pld ) _max = pld; } } if ( _max==-1 ) _max = _min = ploidy->dflt; if ( max ) *max = _max; if ( min ) *min = _min; return 1; } int ploidy_nsex(ploidy_t *ploidy) { return ploidy->nsex; } char *ploidy_id2sex(ploidy_t *ploidy, int id) { if ( id<0 || id>=ploidy->nsex ) return NULL; return ploidy->id2sex[id]; } int ploidy_sex2id(ploidy_t *ploidy, char *sex) { int id; if ( khash_str2int_get(ploidy->sex2id,sex,&id)!=0 ) return -1; return id; } int ploidy_add_sex(ploidy_t *ploidy, const char *sex) { int id; if ( khash_str2int_get(ploidy->sex2id, sex, &id)==0 ) return id; ploidy->nsex++; hts_expand0(char*,ploidy->nsex,ploidy->msex,ploidy->id2sex); ploidy->id2sex[ploidy->nsex-1] = strdup(sex); ploidy->sex2dflt = (int*) realloc(ploidy->sex2dflt,sizeof(int)*ploidy->nsex); ploidy->sex2dflt[ploidy->nsex-1] = ploidy->dflt; return khash_str2int_inc(ploidy->sex2id, ploidy->id2sex[ploidy->nsex-1]); } int ploidy_max(ploidy_t *ploidy) { return ploidy->dflt > ploidy->max ? ploidy->dflt : ploidy->max; } int ploidy_min(ploidy_t *ploidy) { return ploidy->dflt < ploidy->min ? ploidy->dflt : ploidy->min; } bcftools-1.21/ploidy.h000066400000000000000000000104761467060157400147430ustar00rootroot00000000000000/* Copyright (C) 2014-2015 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Lookup from region and sex to ploidy. Example of usage: int default_ploidy = 2; ploidy_t *pld = ploidy_init(fname, default_ploidy); int nsex = ploidy_nsex(pld); int *sex2ploidy = malloc(sizeof(int)*nsex); ploidy_query(pld, "X",60000, sex2ploidy, NULL, NULL); for (i=0; i Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include KHASH_MAP_INIT_INT(gts2smps, uint32_t) #include "bcftools.h" /*! * Flag definitions for args.flag */ #define MISSING (1<<0) #define VERBOSE (1<<1) #define SMPORDER (1<<2) typedef struct _args_t { bcf_srs_t *file; /*! multi-sample VCF file */ bcf_hdr_t *hdr; /*! VCF file header */ FILE *out; /*! output file pointer */ int nsmp; /*! number of samples, can be determined from header but is needed in multiple contexts */ int nsmpp2; /*! 2^(nsmp) (is needed multiple times) */ int *gt_arr; /*! temporary array, to store GTs of current line/record */ int ngt_arr; /*! hold the number of current GT array entries */ uint32_t *bankers; /*! array to store banker's sequence for all possible sample subsets for programmatic indexing into smp_is for output printing, e.g. for three samples A, B and C this would be the following order: [ C, B, A, CB, CA, BA, CBA ] [ 100, 010, 001, 110, 101, 011, 111 ] */ uint64_t *quick; /*! array to store n choose k lookup table of choose() function */ uint8_t flag; /*! several flags, for positions see above*/ uint64_t *missing_gts; /*! array to count missing genotypes of each sample */ uint64_t *smp_is; /*! array to track all possible intersections between samples, with each bit in the index integer belonging to one sample. E.g. for three samples A, B and C, count would be in the following order: [ A, B, AB, C, AC, BC, ABC ] [ 001, 010, 011, 100, 101, 110, 111 ] */ } args_t; static args_t args; uint32_t compute_bankers(unsigned long a); const char *about(void) { return "Count genotype intersections across all possible sample subsets in a vcf file.\n"; } const char *usage(void) { return "\n" "About: Count genotype intersections across all possible sample subsets in a vcf file.\n" "Usage: bcftools +GTisec [General Options] -- [Plugin Options] \n" "\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -m, --missing if set, include count of missing genotypes per sample in output\n" " -v, --verbose if set, annotate count rows with corresponding sample subset lists\n" " -H, --human-readable if set, create human readable output; i.e. sort output by sample and\n" " print each subset's intersection count once for each sample contained\n" " in the subset; implies verbose output (-v)\n" "\n" "Example:\n" " bcftools +GTisec in.vcf -- -v # for verbose output\n" " bcftools +GTisec in.vcf -- -H # for human readable output\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { memset(&args,0,sizeof(args_t)); args.flag = 0; static struct option loptions[] = { {"help", no_argument, 0,'h'}, {"missing", no_argument, 0,'m'}, {"verbose", no_argument, 0,'v'}, {"human-readable", no_argument, 0,'H'}, {0,0,0,0} }; int c; while ((c = getopt_long(argc, argv, "?mvHh",loptions,NULL)) >= 0) { switch (c) { case 'm': args.flag |= MISSING; break; case 'v': args.flag |= VERBOSE; break; case 'H': args.flag |= ( SMPORDER | VERBOSE ); break; case 'h': usage(); break; case '?': default: error("%s", usage()); break; } } if ( optind != argc ) usage(); // too many files given args.hdr = in; if ( !bcf_hdr_nsamples(args.hdr) ) { error("No samples in input file.\n"); } args.nsmp = bcf_hdr_nsamples(args.hdr); if ( args.nsmp > 32 ) error("Too many samples. A maximum of 32 is supported.\n"); args.nsmpp2 = pow( 2, args.nsmp); args.bankers = (uint32_t*) calloc( args.nsmpp2, sizeof(uint32_t) ); args.quick = (uint64_t*) calloc((args.nsmp * (args.nsmp + 1)) / 4, sizeof(unsigned long)); if ( args.flag & MISSING ) args.missing_gts = (uint64_t*) calloc( args.nsmp, sizeof(uint64_t)); args.smp_is = (uint64_t*) calloc( args.nsmpp2, sizeof(uint64_t)); if ( bcf_hdr_id2int(args.hdr, BCF_DT_ID, "GT")<0 ) error("[E::%s] GT not present in the header\n", __func__); args.gt_arr = NULL; args.ngt_arr = 0; args.out = stdout; /*! Header printing */ FILE *fp = args.out; fprintf(fp, "# This file was produced by bcftools +GTisec (%s+htslib-%s)\n", bcftools_version(), hts_version()); fprintf(fp, "# The command line was:\tbcftools +GTisec %s ", argv[0]); int i; for (i=1; i < argc; i++) { fprintf(fp, " %s", argv[i]); } fprintf(fp,"\n"); fprintf(fp,"# This file can be used as input to the subset plotting tools at:\n" "# https://github.com/dlaehnemann/bankers2\n"); fprintf(fp,"# Genotype intersections across samples:\n"); fprintf(fp,"@SMPS"); for (i = args.nsmp-1; i >= 0; i--) { fprintf(fp," %s", bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, i)); } fprintf(fp,"\n"); if ( args.flag & MISSING ) { if ( args.flag & SMPORDER ) { fprintf(fp, "# The first line of each sample contains its count of missing genotypes, with a '-' appended\n" "# to the sample name.\n"); } else { fprintf(fp, "# The first %i lines contain the counts for missing values of each sample in the order provided\n" "# in the SMPS-line above. Intersection counts only start afterwards.\n", args.nsmp); } } if ( args.flag & SMPORDER ) { fprintf(fp, "# Human readable output (-H) was requested. Subset intersection counts are therefore sorted by\n" "# sample and repeated for each contained sample. For each sample, counts are in banker's \n" "# sequence order regarding all other samples.\n"); } else { fprintf(fp, "# Subset intersection counts are in global banker's sequence order.\n"); if ( args.nsmp > 2 ) { fprintf(fp, "# After exclusive sample counts in order of the SMPS-line, banker's sequence continues with:\n" "# %s,%s %s,%s ...\n", bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-1 ), bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-2 ), bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-1 ), bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-3 ) ); } } if (args.flag & VERBOSE ) { fprintf(fp,"# [1] Number of shared non-ref genotypes \t[2] Samples sharing non-ref genotype (GT)\n"); } else { fprintf(fp,"# [1] Number of shared non-ref genotypes\n"); } /* Compute banker's sequence for following printing by sample and * with increasing subset size. */ uint32_t j; for ( j = 0; j < args.nsmpp2; j++ ) { args.bankers[j] = compute_bankers(j); } return 1; } /* ADAPTED CODE FROM CORIN LAWSON (START) * https://github.com/au-phiware/bankers/blob/master/c/bankers.c * who implemented ideas of Eric Burnett: * http://www.thelowlyprogrammer.com/2010/04/indexing-and-enumerating-subsets-of.html */ /* * Compute the binomial coefficient of `n choose k'. * Use the fact that binom(n, k) = binom(n, n - k). * Use a lookup table (triangle, actually) for speed. * Otherwise it's dumb (heart) recursion. * Added relative to Corin Lawson: * * Passing in of sample number through pointer to args struct * * Make quick lookup table external to keep it persistent with clean allocation * and freeing */ uint64_t choose(unsigned int n, unsigned int k) { if (n == 0) return 0; if (n == k || k == 0) return 1; if (k > n / 2) k = n - k; unsigned int i = (n * (n - 1)) / 4 + k - 1; if (args.quick[i] == 0) args.quick[i] = choose(n - 1, k - 1) + choose(n - 1, k); return args.quick[i]; } /* * Returns the Banker's number at the specified position, a. * Derived from the recursive bit flip method. * Added relative to Corin Lawson: * * Uses same lookup table solution as choose function, just * maintained externally to persist across separate function calls. * * Uses bitwise symmetry of banker's sequence to use bitwise inversion * instead of recursive bit flip for second half of sequence. */ uint32_t compute_bankers(unsigned long a) { if (a == 0) return 0; if ( args.bankers[a] == 0 ) { if ( a >= (args.nsmpp2 / 2) ) return args.bankers[a] = ( compute_bankers(args.nsmpp2 - (a+1)) ^ (args.nsmpp2 - 1) ); // use bitwise symmetry of bankers sequence unsigned int c = 0; uint32_t n = args.nsmp; uint64_t e = a, binom; binom = choose(n, c); do { e -= binom; } while ((binom = choose(n, ++c)) <= e); do { if (e == 0 || (binom = choose(n - 1, c - 1)) > e) c--, args.bankers[a] |= 1; else e -= binom; } while (--n && c && ((args.bankers[a] <<= 1) || 1)); args.bankers[a] <<= n; } return args.bankers[a]; } // ADAPTED CODE FROM CORIN LAWSON END /* * GT field (genotype) comparison function. */ bcf1_t *process(bcf1_t *rec) { uint64_t i; bcf_unpack(rec, BCF_UN_FMT); // unpack the Format fields, including the GT field int gte_smp = 0; // number GT array entries per sample (should be 2, one entry per allele) if ( (gte_smp = bcf_get_genotypes(args.hdr, rec, &(args.gt_arr), &(args.ngt_arr) ) ) <= 0 ) { error("GT not present at %s: %"PRId64"\n", args.hdr->id[BCF_DT_CTG][rec->rid].key, (int64_t) rec->pos+1); } gte_smp /= args.nsmp; // divide total number of genotypes array entries (= args.ngt_arr) by number of samples int ret; // stick all genotypes in a hash as keys and store up to 32 samples in a corresponding flag as its value khiter_t bucket; khash_t(gts2smps) *gts = kh_init(gts2smps); // create hash for ( i = 0; i < args.nsmp; i++ ) { int *gt_ptr = args.gt_arr + gte_smp * i; if (bcf_gt_is_missing(gt_ptr[0]) || ( gte_smp == 2 && bcf_gt_is_missing(gt_ptr[1]) ) ) { if ( args.flag & MISSING ) args.missing_gts[i]++; // count missing genotypes, if requested continue; // don't do anything else for missing genotypes, their "sharing" gives no info... } int a = bcf_gt_allele(gt_ptr[0]); int b; if ( gte_smp == 2 ) // two entries available per sample, padded with missing values for haploid genotypes { b = bcf_gt_allele(gt_ptr[1]); } else if (gte_smp == 1 ) // use missing value for second entry in hash key generation below, if only one is available { b = bcf_gt_allele(bcf_int32_vector_end); } else { error("gtisec does not support ploidy higher than 2.\n"); } int idx = bcf_alleles2gt(a,b); // generate genotype specific hash key bucket = kh_get(gts2smps, gts, idx); // get the genotype's hash bucket if ( bucket == kh_end(gts) ) { // means that key does not exist bucket = kh_put(gts2smps, gts, idx, &ret); // create bucket with genotype index as key and return its iterator kh_val(gts, bucket) = 0; // initialize the bucket with all sample bits unset } kh_value(gts, bucket) |= (1<= 0; s--) { if ( args.flag & MISSING ) // if missing genotype counts are requested, print them to standard output { fprintf(fp, "%"PRIu64"\t%s-\n", args.missing_gts[s], bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s)); } for ( i = 1; i < args.nsmpp2; i++ ) { if ( (args.bankers[i]>>s) & 1 ) { fprintf(fp, "%"PRIu64"\t", args.smp_is[ args.bankers[i] ]); // print out count of genotypes shared by samples in current banker's sequence position int j; /* Print sample list */ fprintf(fp, "%s", bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s)); // print current sample first for ( j = args.nsmp-1; j >= 0; j-- ) { if ( (args.bankers[i] ^ (1<= 0; s--) { fprintf(fp, "%"PRIu64"\t%s-\n", args.missing_gts[s], bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s)); } } for ( i = 1; i < args.nsmpp2; i++ ) { fprintf(fp, "%"PRIu64"\t", args.smp_is[ args.bankers[i] ]); // print out count of genotypes shared by samples in current banker's sequence position int j = 0; for ( s = args.nsmp-1; s >= 0; s--) { if ( (args.bankers[i]>>s) & 1 ) { fprintf(fp, "%s%s", j ? "," : "", bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s) ); // samples in specified order j = 1; } } fprintf(fp, "\n" ); } } else { if ( args.flag & MISSING ) // if missing genotype counts are requested, print them to standard output { for ( s = args.nsmp-1; s >= 0; s--) { fprintf(fp, "%"PRIu64"\n", args.missing_gts[s]); } } for ( i = 1; i < args.nsmpp2; i++ ) { fprintf(fp, "%"PRIu64"\n", args.smp_is[ args.bankers[i] ]); // print out count of genotypes shared by samples in current banker's sequence position } } fclose(fp); /* freeing up args */ free(args.gt_arr); free(args.bankers); free(args.quick); if (args.flag & MISSING) free(args.missing_gts); free(args.smp_is); } bcftools-1.21/plugins/GTisec.mk000066400000000000000000000002611467060157400164510ustar00rootroot00000000000000plugins/GTisec.so: plugins/GTisec.c version.h version.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/GTsubset.c000066400000000000000000000210031467060157400166430ustar00rootroot00000000000000/* plugins/GTsubset.c -- output only positions where the selected samples exclusively share a genotype, i.e. all selected samples must have the same genotype (including both alleles) and none of the unselected samples can have the same genotype Copyright (C) 2016 Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany Author: David Laehnemann Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include "bcftools.h" typedef struct _args_t { bcf_hdr_t *hdr; /*! VCF file header */ int *gt_arr; /*! temporary array, to store GTs of current line/record */ int ngt_arr; /*! hold the number of current GT array entries */ int nsmp; /*! number of samples, can be determined from header but is needed in multiple contexts */ int n_sel_smps; /*! number of selected samples who should exclusively share genotypes */ int *selected_smps; /*! pointer to start of array containing 1 at indices corresponding to selected samples in header dict and 0 at others*/ } args_t; static args_t args; const char *about(void) { return "Output only sites where the requested samples all exclusively share a genotype (GT).\n"; } const char *usage(void) { return "\n" "About: Output only sites where the requested samples all exclusively share a genotype (GT), i.e.\n" " all selected samples must have the same GT, while non of the others can have it.\n" "Usage: bcftools +GTsubset [General Options] -- [Plugin Options] \n" "\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -s,--sample-list comma-separated list of samples; only those sites where all of these\n" " samples exclusively share their genotype are given as output\n" "\n" "Example:\n" " bcftools +GTsubset in.vcf -- -s SMP1,SMP2 \n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { memset(&args,0,sizeof(args_t)); int i; static struct option loptions[] = { {"help", no_argument, 0,'h'}, {"sample-list", required_argument, 0,'s'}, {0,0,0,0} }; char **smps_strs = NULL; int c; while ((c = getopt_long(argc, argv, "?s:h",loptions,NULL)) >= 0) { switch (c) { case 's': smps_strs = hts_readlist(optarg,0,&(args.n_sel_smps)); if ( args.n_sel_smps == 0 ) { fprintf(stderr, "Sample specification not valid.\n"); error("%s", usage()); } break; case 'h': usage(); break; case '?': default: error("%s", usage()); break; } } if ( optind != argc ) usage(); // too many files given args.hdr = bcf_hdr_dup(in); // Samples parsing from header and input option if ( !bcf_hdr_nsamples(args.hdr) ) { error("No samples in input file.\n"); } args.nsmp = bcf_hdr_nsamples(args.hdr); args.selected_smps = (int*) calloc(args.nsmp,sizeof(int)); for ( i = 0; i < args.n_sel_smps; i++ ) { int ind = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, smps_strs[i]); if ( ind == -1 ) { error("Sample '%s' not in input vcf file.\n", smps_strs[i]); } else { args.selected_smps[ind] = 1; } free(smps_strs[i]); } free(smps_strs); /* fprintf(stderr, "Selected samples array:["); for (i=0;iid[BCF_DT_CTG][rec->rid].key, (int64_t) rec->pos+1); } gte_smp /= args.nsmp; // divide total number of genotypes array entries (= args.ngt_arr) by number of samples // initialize with missing genotype int a1 = 0; int a2 = 0; // initialize with first selected sample genotype that is not missing int gt = -1; while ( (a1 == 0) || (a2 == 0) ) { gt++; if (gt == args.nsmp) break; if (args.selected_smps[gt] == 0) continue; a1 = (args.gt_arr + gte_smp * gt)[0]; if ( gte_smp == 2 ) a2 = (args.gt_arr + gte_smp * gt)[1]; else if ( gte_smp == 1 ) a2 = bcf_int32_vector_end; else error("GTsubset does not support ploidy higher than 2.\n"); } // fprintf(stderr, "a1: %i a2: %i\n", a1, a2); // check all genotypes if they match (for included samples) or disagree (for samples not included) gt = 0; for ( i = 0; i < args.nsmp; i++ ) { int *gt_ptr = args.gt_arr + gte_smp * i; int b1 = gt_ptr[0]; int b2; if ( gte_smp == 2 ) // two entries available per sample, padded with missing values for haploid genotypes { b2 = gt_ptr[1]; } else if (gte_smp == 1 ) // use vector end value for second entry, if only one is available { b2 = bcf_int32_vector_end; } else { error("GTsubset does not support ploidy higher than 2.\n"); } // fprintf(stderr, "b1: %i b2: %i\n", b1, b2); /* missing genotypes are counted as always passing, as they neither * mismatch the initial selected genotype for a selected sample, nor * do they match the initial selected genotype for an excluded sample's * genotype */ if ( (b1 == 0) || (b2 == 0) ) { gt++; // fprintf(stderr, "missing => pass\n"); continue; } else if ( args.selected_smps[i] == 1 ) { if ( (b1 == a1) && (b2 == a2) ) { gt++; // fprintf(stderr, "match => pass\n"); continue; } else { // fprintf(stderr, "no match => fail\n"); break; } } else if ( args.selected_smps[i] == 0 ) { if ( (b1 != a1 ) || (b2 != a2) ) { gt++; // fprintf(stderr, "no match => pass\n"); continue; } else { // fprintf(stderr, "match => fail\n"); break; } } } if ( gt == args.nsmp ) { return rec; } else { return NULL; } } void destroy(void) { /* freeing up args */ bcf_hdr_destroy(args.hdr); free(args.gt_arr); free(args.selected_smps); } bcftools-1.21/plugins/GTsubset.mk000066400000000000000000000002651467060157400170370ustar00rootroot00000000000000plugins/GTsubset.so: plugins/GTsubset.c version.h version.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/ad-bias.c000066400000000000000000000274601467060157400164200ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2020 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "convert.h" typedef struct { int smpl,ctrl; // VCF sample index const char *smpl_name, *ctrl_name; } pair_t; typedef struct { bcf_hdr_t *hdr; pair_t *pair; int npair, mpair, min_dp, min_alt_dp; int32_t *ad_arr; int mad_arr; double th; convert_t *convert; kstring_t str; uint64_t nsite,ncmp; int variant_type; int clean_vcf; kbitset_t *rm_als; } args_t; args_t args; const char *about(void) { return "Find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD).\n"; } const char *usage(void) { return "\n" "About: Find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD).\n" "Usage: bcftools +ad-bias [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -a, --min-alt-dp Minimum required alternate allele depth [1]\n" " -c, --clean-vcf Outputs VCF removing sites and ALT alleles not passing the -t threshold\n" " -d, --min-dp Minimum required depth [0]\n" " -f, --format Optional tags to append to output (`bcftools query` style of format)\n" " -s, --samples List of sample pairs, one tab-delimited pair per line\n" " -t, --threshold Output only hits with p-value smaller than [1e-3]\n" " -v, --variant-type Consider only variants of this type. (By default all variants are considered.)\n" "\n" "Example:\n" " bcftools +ad-bias file.bcf -- -t 1e-3 -s samples.txt\n" "\n"; } void parse_samples(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); kstring_t str = {0,0,0}; if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); int moff = 0, *off = NULL; do { // HPSI0513i-veqz_6 HPSI0513pf-veqz int ncols = ksplit_core(str.s,'\t',&moff,&off); if ( ncols<2 ) error("Could not parse the sample file: %s\n", str.s); int smpl = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[0]]); if ( smpl<0 ) continue; int ctrl = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); if ( ctrl<0 ) continue; args->npair++; hts_expand0(pair_t,args->npair,args->mpair,args->pair); pair_t *pair = &args->pair[args->npair-1]; pair->ctrl = ctrl; pair->smpl = smpl; pair->smpl_name = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,pair->smpl); pair->ctrl_name = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,pair->ctrl); } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { memset(&args,0,sizeof(args_t)); args.hdr = in; args.th = 1e-3; args.min_alt_dp = 1; char *fname = NULL, *format = NULL; static struct option loptions[] = { {"clean-vcf",required_argument,NULL,'c'}, {"min-dp",required_argument,NULL,'d'}, {"min-alt-dp",required_argument,NULL,'a'}, {"format",required_argument,NULL,'f'}, {"samples",required_argument,NULL,'s'}, {"threshold",required_argument,NULL,'t'}, {"variant-type",required_argument,NULL,'v'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "?hs:t:f:d:a:v:c",loptions,NULL)) >= 0) { switch (c) { case 'c': args.clean_vcf = 1; break; case 'a': args.min_alt_dp = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse: -a %s\n", optarg); break; case 'd': args.min_dp = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse: -d %s\n", optarg); break; case 't': args.th = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -t %s\n", optarg); break; case 's': fname = optarg; break; case 'v': if ( !strcasecmp(optarg,"snp") || !strcasecmp(optarg,"snps") ) args.variant_type = VCF_SNP; else if ( !strcasecmp(optarg,"indel") || !strcasecmp(optarg,"indels") ) args.variant_type = VCF_INDEL; else error("Error: Variant type \"%s\" is not supported\n",optarg); break; case 'f': format = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } if ( !fname ) error("Expected the -s option\n"); parse_samples(&args, fname); if ( format ) { if ( args.clean_vcf ) error("The option -f cannot be used together with -c\n"); args.convert = convert_init(args.hdr, NULL, 0, format); } if ( args.clean_vcf ) return 0; printf("# This file was produced by: bcftools +ad-bias(%s+htslib-%s)\n", bcftools_version(),hts_version()); printf("# The command line was:\tbcftools +ad-bias %s", argv[0]); for (c=1; cn_allele < 2 ) return NULL; int nad = bcf_get_format_int32(args.hdr, rec, "AD", &args.ad_arr, &args.mad_arr); if ( nad<0 ) return NULL; nad /= bcf_hdr_nsamples(args.hdr); if ( args.convert ) convert_line(args.convert, rec, &args.str); args.nsite++; int keep_als = 0; if ( args.clean_vcf ) { if ( !args.rm_als ) args.rm_als = kbs_init(rec->n_allele); else if ( args.rm_als->n_max < rec->n_allele ) kbs_resize(&args.rm_als, rec->n_allele); kbs_insert_all(args.rm_als); } int i,j; for (i=0; ismpl; int32_t *bptr = args.ad_arr + nad*pair->ctrl; // Find the two most frequent alleles int nbig=-1,nsmall=-1,ibig=-1,ismall=-1; for (j=0; jd.allele[ibig])!=strlen(rec->d.allele[ismall]) ) continue; if ( args.variant_type==VCF_INDEL && strlen(rec->d.allele[ibig])==strlen(rec->d.allele[ismall]) ) continue; } int iref,ialt,nalt; if ( ibig > ismall ) ialt = ibig, iref = ismall, nalt = nbig; else ialt = ismall, iref = ibig, nalt = nsmall; if ( nalt < args.min_alt_dp ) continue; args.ncmp++; int n11 = aptr[iref], n12 = aptr[ialt]; int n21 = bptr[iref], n22 = bptr[ialt]; double left, right, fisher; kt_fisher_exact(n11,n12,n21,n22, &left,&right,&fisher); if ( fisher >= args.th ) continue; if ( args.clean_vcf ) { keep_als = 1; kbs_delete(args.rm_als, ialt); continue; } printf("FT\t%s\t%s\t%s\t%"PRId64"\t%s\t%s\t%d\t%d\t%d\t%d\t%e", pair->smpl_name,pair->ctrl_name, bcf_hdr_id2name(args.hdr,rec->rid), (int64_t) rec->pos+1, rec->d.allele[iref],rec->d.allele[ialt], n11,n12,n21,n22, fisher ); if ( args.convert ) printf("\t%s", args.str.s); printf("\n"); } if ( keep_als ) { kbs_delete(args.rm_als, 0); bcf_unpack(rec,BCF_UN_ALL); if ( bcf_remove_allele_set(args.hdr, rec, args.rm_als)!=0 ) error("Failed to subset alleles\n"); return rec; } return NULL; } void destroy(void) { if ( !args.clean_vcf ) { printf("# SN, Summary Numbers\t[2]Number of Pairs\t[3]Number of Sites\t[4]Number of comparisons\t[5]P-value output threshold\n"); printf("SN\t%d\t%"PRId64"\t%"PRId64"\t%e\n",args.npair,args.nsite,args.ncmp,args.th); } if ( args.rm_als ) kbs_destroy(args.rm_als); if (args.convert) convert_destroy(args.convert); free(args.str.s); free(args.pair); free(args.ad_arr); } bcftools-1.21/plugins/ad-bias.mk000066400000000000000000000003201467060157400165670ustar00rootroot00000000000000plugins/ad-bias.so: plugins/ad-bias.c version.h version.c convert.h convert.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ convert.c version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/add-variantkey.c000066400000000000000000000055771467060157400200300ustar00rootroot00000000000000/* plugins/add-variantkey.c -- add VariantKey INFO field. Copyright (C) 2017-2018 GENOMICS plc. Author: Nicola Asuni Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "../variantkey.h" bcf_hdr_t *in_hdr, *out_hdr; const char *about(void) { return "Add VariantKey INFO fields VKX and RSX.\n"; } const char *usage(void) { return "\n" "About: Add VKX and RSX columns.\n" "Usage: bcftools +add-variantkey [General Options] \n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Example:\n" " bcftools +add-variantkey in.vcf\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { in_hdr = in; out_hdr = out; bcf_hdr_append(out_hdr, "##INFO="); bcf_hdr_append(out_hdr, "##INFO="); return 0; } bcf1_t *process(bcf1_t *rec) { uint64_t vk = variantkey( in_hdr->id[BCF_DT_CTG][rec->rid].key, strlen(in_hdr->id[BCF_DT_CTG][rec->rid].key), rec->pos, rec->d.allele[0], strlen(rec->d.allele[0]), rec->d.allele[1], strlen(rec->d.allele[1])); char vs[17]; variantkey_hex(vk, vs); bcf_update_info_string(out_hdr, rec, "VKX", vs); char rsid[9]; char *ptr = rec->d.id; ptr += 2; // remove 'rs' sprintf(rsid, "%08" PRIx32, (uint32_t)strtoul(ptr, NULL, 10)); bcf_update_info_string(out_hdr, rec, "RSX", rsid); return rec; } void destroy(void) { } bcftools-1.21/plugins/af-dist.c000066400000000000000000000166511467060157400164470ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "bcftools.h" #include "bin.h" typedef struct { char *af_tag; bcf_hdr_t *hdr; int32_t *gt, ngt, naf; float *af, list_min, list_max; bin_t *dev_bins, *prob_bins; uint64_t *dev_dist, *prob_dist; } args_t; args_t *args; const char *about(void) { return "AF and GT probability distribution stats.\n"; } const char *usage(void) { return "\n" "About: Collect AF deviation stats and GT probability distribution given AF and\n" " assuming HWE. Only non-reference genotypes with known allele frequency\n" " at the site are considered, their probabilities are 2*AF*(1-AF) for RA\n" " and AF**2 for the AA genotype.\n" "Usage: bcftools +af-dist [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -d, --dev-bins AF deviation bins\n" " -l, --list list genotypes from the given bin (for debugging)\n" " -p, --prob-bins probability distribution bins\n" " -t, --af-tag VCF INFO tag to use [AF]\n" "\n" "Default binning:\n" " -d: 0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1\n" " -p: 0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1\n" "Example:\n" " bcftools +af-dist file.bcf -- -t EUR_AF -p bins.txt\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { args = (args_t*) calloc(1,sizeof(args_t)); char *dev_bins = "0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1"; char *prob_bins = "0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1"; args->hdr = in; args->af_tag = "AF"; args->list_min = -1; static struct option loptions[] = { {"list",required_argument,NULL,'l'}, {"dev-bins",required_argument,NULL,'d'}, {"prob-bins",required_argument,NULL,'p'}, {"af-tag",required_argument,NULL,'t'}, {NULL,0,NULL,0} }; int c; while ((c = getopt_long(argc, argv, "?ht:d:p:l:",loptions,NULL)) >= 0) { switch (c) { case 'l': { char *a,*b; args->list_min = strtod(optarg,&a); if ( a==optarg || *a!=',' ) error("Could not parse: --list %s\n", optarg); args->list_max = strtod(a+1,&b); if ( a+1==b || *b ) error("Could not parse: --list %s\n", optarg); break; } case 'd': dev_bins = optarg; break; case 'p': prob_bins = optarg; break; case 't': args->af_tag = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } args->dev_bins = bin_init(dev_bins,0,1); int nbins = bin_get_size(args->dev_bins); args->dev_dist = (uint64_t*)calloc(nbins,sizeof(*args->dev_dist)); args->prob_bins = bin_init(prob_bins,0,1); nbins = bin_get_size(args->prob_bins); args->prob_dist = (uint64_t*)calloc(nbins,sizeof(*args->prob_dist)); printf("# This file was produced by: bcftools +af-dist(%s+htslib-%s)\n", bcftools_version(),hts_version()); printf("# The command line was:\tbcftools +af-dist %s", argv[0]); for (c=1; clist_min!=-1 ) printf("# GT, genotypes with P(AF) in [%f,%f]; [2]Chromosome\t[3]Position[4]Sample\t[5]Genotype\t[6]AF-based probability\n",args->list_min,args->list_max); return 1; } bcf1_t *process(bcf1_t *rec) { int naf = bcf_get_info_float(args->hdr,rec,args->af_tag,&args->af,&args->naf); if ( naf<=0 ) return NULL; float af = args->af[0]; float pRA = 2*af*(1-af); float pAA = af*af; int iRA = bin_get_idx(args->prob_bins,pRA); int iAA = bin_get_idx(args->prob_bins,pAA); int list_RA = args->list_min==-1 || pRA < args->list_min || pRA > args->list_max ? 0 : 1; int list_AA = args->list_min==-1 || pAA < args->list_min || pAA > args->list_max ? 0 : 1; const char *chr = bcf_seqname(args->hdr,rec); int ngt = bcf_get_genotypes(args->hdr, rec, &args->gt, &args->ngt); int i, j, nsmpl = bcf_hdr_nsamples(args->hdr); int nals = 0, nalt = 0; ngt /= nsmpl; for (i=0; igt + i*ngt; int dosage = 0; for (j=0; jprob_dist[iRA]++; if ( list_RA ) printf("GT\t%s\t%"PRId64"\t%s\t1\t%f\n",chr,(int64_t) rec->pos+1,args->hdr->samples[i],pRA); } else if ( dosage==2 ) { args->prob_dist[iAA]++; if ( list_AA ) printf("GT\t%s\t%"PRId64"\t%s\t2\t%f\n",chr,(int64_t) rec->pos+1,args->hdr->samples[i],pAA); } } if ( nals && (nalt || af) ) { float af_dev = fabs(af - (float)nalt/nals); int iAF = bin_get_idx(args->dev_bins,af_dev); args->dev_dist[iAF]++; } return NULL; } void destroy(void) { printf("# PROB_DIST, genotype probability distribution, assumes HWE\n"); int i, n; n = bin_get_size(args->prob_bins); for (i=0; iprob_bins,i); float max = bin_get_value(args->prob_bins,i+1); printf("PROB_DIST\t%f\t%f\t%"PRId64"\n", min,max,args->prob_dist[i]); } printf("# DEV_DIST, distribution of AF deviation, based on %s and INFO/AN, AC calculated on the fly\n", args->af_tag); n = bin_get_size(args->dev_bins); for (i=0; idev_bins,i); float max = bin_get_value(args->dev_bins,i+1); printf("DEV_DIST\t%f\t%f\t%"PRId64"\n", min,max,args->dev_dist[i]); } bin_destroy(args->dev_bins); bin_destroy(args->prob_bins); free(args->dev_dist); free(args->prob_dist); free(args->gt); free(args->af); free(args); } bcftools-1.21/plugins/af-dist.mk000066400000000000000000000003041467060157400166200ustar00rootroot00000000000000plugins/af-dist.so: plugins/af-dist.c version.h version.c bin.h bin.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ bin.c version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/allele-length.c000066400000000000000000000071531467060157400176320ustar00rootroot00000000000000/* plugins/allele-length.c -- Calculate stats about the length of alleles Copyright (C) 2017-2018 GENOMICS plc. Copyright (C) 2023 Genome Research Ltd. Author: Nicola Asuni Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #define MAXLEN 512 static uint64_t numvar; static uint64_t numxvar; static uint64_t reflen[MAXLEN]; static uint64_t altlen[MAXLEN]; static uint64_t refaltlen[MAXLEN]; static uint64_t xrefaltlen[MAXLEN]; const char *about(void) { return "Count the frequency of the length of REF, ALT and REF+ALT\n"; } const char *usage(void) { return "\n" "About: Count the frequency of the length of alleles.\n" "Usage: bcftools +allele-length [General Options] \n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Example:\n" " bcftools +allele-length in.vcf\n" "\n"; } // return 0 if the string contains characters other than standard ACGT base letters int contain_non_base(const char *str) { int c; while ((c = *str++)) { if ((c != 'A') && (c != 'a') && (c != 'C') && (c != 'c') && (c != 'G') && (c != 'g') && (c != 'T') && (c != 't')) { return 1; } } return 0; } // Called once at startup, it initializes local variables. // Return 1 to suppress VCF/BCF header from printing, 0 otherwise. int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { numvar = 0; int i = 0; for(i = 0; i < MAXLEN; i++) { reflen[i] = 0; altlen[i] = 0; refaltlen[i] = 0; xrefaltlen[i] = 0; } return 1; } // Called for each VCF record. Return rec to output the line or NULL to suppress output. bcf1_t *process(bcf1_t *rec) { int rl = strlen(rec->d.allele[0]); int al = strlen(rec->d.allele[1]); int ral = rl + al; if ( rl >= MAXLEN ) rl = MAXLEN - 1; if ( al >= MAXLEN ) al = MAXLEN - 1; if ( ral >= MAXLEN ) ral = MAXLEN - 1; reflen[rl] += 1; altlen[al] += 1; refaltlen[ral] += 1; if ((contain_non_base(rec->d.allele[0])) || (contain_non_base(rec->d.allele[1]))) { xrefaltlen[ral] += 1; numxvar++; } numvar++; return NULL; } // Print final output void destroy(void) { int i = 0; printf("LENGTH\tREF\tALT\tREF+ALT\tREF+ALT WITH NON-BASE NUCLEOTIDES\n"); for(i = 0; i < MAXLEN; i++) { printf("%d\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"\n", i, reflen[i], altlen[i], refaltlen[i], xrefaltlen[i]); } printf("\t\t\t%"PRIu64"\t%"PRIu64"\n", numvar, numxvar); } bcftools-1.21/plugins/check-ploidy.c000066400000000000000000000141101467060157400174570ustar00rootroot00000000000000/* Copyright (C) 2017-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" typedef struct { char *sample; int beg,end,ploidy; } dat_t; typedef struct { int argc; char **argv; int rid, gt_id, ndat, ignore_missing; dat_t *dat; bcf_hdr_t *hdr; } args_t; static args_t *args; const char *about(void) { return "Check if ploidy of samples is consistent for all sites\n"; } const char *usage(void) { return "\n" "About: Check if ploidy of samples is consistent for all sites.\n" "Usage: bcftools +check-ploidy [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -m, --use-missing use missing and half-missing genotypes such as ., ./., 0/1\n" "\n" "Example:\n" " # report ploidy, ignore missing genotypes\n" " bcftools +check-ploidy file.bcf\n" "\n" " # use missing genotypes\n" " bcftools +check-ploidy file.bcf -- -m\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; if ( !in ) error("%s",usage()); args->ignore_missing = 1; static struct option loptions[] = { {"use-missing",0,0,'m'}, {0,0,0,0} }; int c; while ((c = getopt_long(argc, argv, "?hm",loptions,NULL)) >= 0) { switch (c) { case 'm': args->ignore_missing = 0; break; case 'h': case '?': default: error("%s", usage()); break; } } args->hdr = in; args->ndat = bcf_hdr_nsamples(args->hdr); args->dat = (dat_t*) calloc(args->ndat,sizeof(dat_t)); int i; for (i=0; indat; i++) args->dat[i].sample = args->hdr->samples[i]; args->rid = -1; args->gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); if ( args->gt_id<0 ) error("Error: GT field is not present\n"); printf("# [1]Sample\t[2]Chromosome\t[3]Region Start\t[4]Region End\t[5]Ploidy\n"); return 1; } bcf1_t *process(bcf1_t *rec) { int i; bcf_unpack(rec, BCF_UN_FMT); bcf_fmt_t *fmt_gt = NULL; for (i=0; in_fmt; i++) if ( rec->d.fmt[i].id==args->gt_id ) { fmt_gt = &rec->d.fmt[i]; break; } if ( !fmt_gt ) return NULL; // no GT tag if ( args->ndat != rec->n_sample ) error("Incorrect number of samples at %s:%"PRId64" .. found %d, expected %d\n",bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,rec->n_sample,args->ndat); if ( args->rid!=rec->rid && args->rid!=-1 ) { for (i=0; indat; i++) { dat_t *dat = &args->dat[i]; if ( dat->ploidy!=0 ) printf("%s\t%s\t%d\t%d\t%d\n", dat->sample,bcf_hdr_id2name(args->hdr, args->rid),dat->beg+1,dat->end+1,dat->ploidy); dat->ploidy = 0; } } args->rid = rec->rid; #define BRANCH_INT(type_t,vector_end) \ { \ for (i=0; in_sample; i++) \ { \ type_t *p = (type_t*) (fmt_gt->p + i*fmt_gt->size); \ int nal, missing = 0; \ for (nal=0; naln; nal++) \ { \ if ( p[nal]==vector_end ) break; /* smaller ploidy */ \ if ( bcf_gt_is_missing(p[nal]) && args->ignore_missing ) { missing=1; break; } /* missing allele */ \ } \ if ( !nal || missing ) continue; /* missing genotype */ \ dat_t *dat = &args->dat[i]; \ if ( dat->ploidy==nal ) \ { \ dat->end = rec->pos; \ continue; \ } \ if ( dat->ploidy!=0 ) \ printf("%s\t%s\t%d\t%d\t%d\n", dat->sample,bcf_seqname(args->hdr,rec),dat->beg+1,dat->end+1,dat->ploidy); \ dat->ploidy = nal; \ dat->beg = rec->pos; \ dat->end = rec->pos; \ } \ } switch (fmt_gt->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break; default: error("The GT type is not recognised: %d at %s:%"PRId64"\n",fmt_gt->type, bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); break; } #undef BRANCH_INT return NULL; } void destroy(void) { int i; for (i=0; indat; i++) { dat_t *dat = &args->dat[i]; if ( dat->ploidy!=0 ) printf("%s\t%s\t%d\t%d\t%d\n", dat->sample,bcf_hdr_id2name(args->hdr,args->rid),dat->beg+1,dat->end+1,dat->ploidy); dat->ploidy = 0; } free(args->dat); free(args); } bcftools-1.21/plugins/check-sparsity.c000066400000000000000000000225021467060157400200410ustar00rootroot00000000000000/* Copyright (C) 2017 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" typedef struct { int argc; char **argv, *fname, *region, **regs; int region_is_file, nregs, regs_free; int *smpl, nsmpl, *nsites, min_sites, gt_id; kstring_t tmps; bcf1_t *rec; tbx_t *tbx; hts_idx_t *idx; hts_itr_t *itr; htsFile *fp; bcf_hdr_t *hdr; } args_t; const char *about(void) { return "Print samples without genotypes in a region or chromosome\n"; } static const char *usage_text(void) { return "\n" "About: Print samples without genotypess in a region (-r/-R) or chromosome (the default)\n" "\n" "Usage: bcftools +check-sparsity [Plugin Options]\n" "Plugin options:\n" " -n, --n-markers minimum number of required markers [1]\n" " -r, --regions restrict to comma-separated list of regions\n" " -R, --regions-file restrict to regions listed in a file\n" "\n"; } static void init_data(args_t *args) { args->fp = hts_open(args->fname,"r"); if ( !args->fp ) error("Could not read %s\n", args->fname); args->hdr = bcf_hdr_read(args->fp); if ( !args->hdr ) error("Could not read the header: %s\n", args->fname); args->rec = bcf_init1(); args->gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); if ( args->gt_id<0 ) error("Error: GT field is not present\n"); int i; args->nsmpl = bcf_hdr_nsamples(args->hdr); args->nsites = (int*) calloc(args->nsmpl, sizeof(int)); args->smpl = (int*) malloc(sizeof(int)*args->nsmpl); for (i=0; insmpl; i++) args->smpl[i] = i; if ( strcmp("-",args->fname) ) // not reading from stdin { if ( hts_get_format(args->fp)->format==vcf ) { args->tbx = tbx_index_load(args->fname); if ( !args->tbx && args->region ) error("Could not load the VCF index, please drop the -r/-R option\n"); } else if ( hts_get_format(args->fp)->format==bcf ) { args->idx = bcf_index_load(args->fname); if ( !args->idx && args->region ) error("Could not load the BCF index, please drop the -r/-R option\n"); } } else if ( args->region ) error("Cannot use index with this file, please drop the -r/-R option\n"); if ( args->tbx || args->idx ) { if ( args->region ) { args->regs = hts_readlist(args->region, args->region_is_file, &args->nregs); if ( !args->regs ) error("Could not parse regions: %s\n", args->region); args->regs_free = 1; } else args->regs = (char**) (args->tbx ? tbx_seqnames(args->tbx, &args->nregs) : bcf_index_seqnames(args->idx, args->hdr, &args->nregs)); } } static void destroy_data(args_t *args) { int i; if ( args->regs_free ) for (i=0; inregs; i++) free(args->regs[i]); free(args->regs); bcf_hdr_destroy(args->hdr); bcf_destroy(args->rec); free(args->tmps.s); free(args->smpl); free(args->nsites); if ( args->itr ) hts_itr_destroy(args->itr); if ( args->tbx ) tbx_destroy(args->tbx); if ( args->idx ) hts_idx_destroy(args->idx); if ( hts_close(args->fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fname); } static void report(args_t *args, const char *reg) { int i; for (i=0; insmpl; i++) printf("%s\t%s\n", reg, args->hdr->samples[args->smpl[i]]); args->nsmpl = bcf_hdr_nsamples(args->hdr); for (i=0; insmpl; i++) args->smpl[i] = i; memset(args->nsites, 0, sizeof(int)*args->nsmpl); } static void test_region(args_t *args, char *reg) { if ( args->tbx ) { args->itr = tbx_itr_querys(args->tbx,reg); if ( !args->itr ) return; } else if ( args->idx ) { args->itr = bcf_itr_querys(args->idx,args->hdr,reg); if ( !args->itr ) return; } int ret,i, rid = -1, nread = 0; while (1) { if ( args->tbx ) { if ( (ret=tbx_itr_next(args->fp, args->tbx, args->itr, &args->tmps)) < 0 ) break; // no more lines ret = vcf_parse1(&args->tmps, args->hdr, args->rec); if ( ret<0 ) error("Could not parse the line: %s\n", args->tmps.s); } else if ( args->idx ) { ret = bcf_itr_next(args->fp, args->itr, args->rec); if ( ret < -1 ) error("Could not parse a line from %s\n", reg); if ( ret < 0 ) break; // no more lines or an error } else { if ( args->fp->format.format==vcf ) { if ( (ret=hts_getline(args->fp, KS_SEP_LINE, &args->tmps)) < 0 ) break; // no more lines ret = vcf_parse1(&args->tmps, args->hdr, args->rec); if ( ret<0 ) error("Could not parse the line: %s\n", args->tmps.s); } else if ( args->fp->format.format==bcf ) { ret = bcf_read1(args->fp, args->hdr, args->rec); if ( ret < -1 ) error("Could not parse %s\n", args->fname); if ( ret < 0 ) break; // no more lines or an error } if ( rid!=-1 && rid!=args->rec->rid ) { report(args, bcf_hdr_id2name(args->hdr,rid)); nread = 0; } rid = args->rec->rid; } bcf_unpack(args->rec, BCF_UN_FMT); bcf_fmt_t *fmt_gt = NULL; for (i=0; irec->n_fmt; i++) if ( args->rec->d.fmt[i].id==args->gt_id ) { fmt_gt = &args->rec->d.fmt[i]; break; } if ( !fmt_gt ) continue; // no GT tag if ( fmt_gt->n==0 ) continue; // empty?! if ( fmt_gt->type!=BCF_BT_INT8 ) error("TODO: the GT fmt_type is not int8!\n"); // update the array of missing samples for (i=0; insmpl; i++) { int8_t *ptr = (int8_t*) (fmt_gt->p + args->smpl[i]*fmt_gt->size); int ial = 0; for (ial=0; ialn; ial++) if ( ptr[ial]==bcf_gt_missing || ptr[ial]==bcf_int8_vector_end ) break; if ( ial==0 ) continue; // missing if ( ++args->nsites[i] < args->min_sites ) continue; if ( i+1nsmpl ) { memmove(args->smpl+i, args->smpl+i+1, sizeof(int)*(args->nsmpl-i-1)); memmove(args->nsites+i, args->nsites+i+1, sizeof(int)*(args->nsmpl-i-1)); } args->nsmpl--; i--; } nread = 1; if ( !args->nsmpl ) break; } if ( nread ) report(args, rid==-1 ? reg : bcf_hdr_id2name(args->hdr,rid)); tbx_itr_destroy(args->itr); args->itr = NULL; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->min_sites = 1; static struct option loptions[] = { {"n-markers",required_argument,NULL,'n'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {NULL,0,NULL,0} }; int c,i; char *tmp; while ((c = getopt_long(argc, argv, "vr:R:n:",loptions,NULL)) >= 0) { switch (c) { case 'n': args->min_sites = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse: -n %s\n", optarg); break; case 'R': args->region_is_file = 1; // fall-through case 'r': args->region = optarg; break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else error("%s",usage_text()); } else args->fname = argv[optind]; init_data(args); for (i=0; inregs; i++) test_region(args, args->regs[i]); if ( !args->nregs ) test_region(args, NULL); destroy_data(args); free(args); return 0; } bcftools-1.21/plugins/color-chrs.c000066400000000000000000000477441467060157400172020ustar00rootroot00000000000000/* The MIT License Copyright (c) 2015 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Trio haplotypes: mother (A,B), father (C,D), child (E,F) Modeling the following states: 01|23|02 01|23|03 01|23|12 01|23|13 01|23|20 01|23|30 01|23|21 01|23|31 with the likelihoods of two haplotypes A,B segments sharing an allele: P(01|A==B) .. e (P of error) P(00|A==B) .. 1-e and P(ab,cd,ef|E=A,F=C) = P(ea|E=A)*P(fc|F=C) Unrelated samples: (A,B) and (C,D) Modeling the states: xxxx .. A!=C,A!=D,B!=C,B!=D 0x0x .. A=C,B!=D 0xx0 .. A=D,B!=C x00x .. B=C,A!=D x0x0 .. B=D,A!=C 0101 .. A=C,B=D 0110 .. A=D,B=C with the likelihoods P(01|A!=B) .. f*(1-f) P(00|A!=B) .. (1-f)*(1-f) P(11|A!=B) .. f*f Assuming 2x30 crossovers, P=2e-8. */ #include #include #include #include #include #include #include #include "bcftools.h" #include "HMM.h" #define C_TRIO 1 #define C_UNRL 2 // states for unrelated samples #define UNRL_xxxx 0 #define UNRL_0x0x 1 #define UNRL_0xx0 2 #define UNRL_x00x 3 #define UNRL_x0x0 4 #define UNRL_0101 5 #define UNRL_0110 6 // trio states #define TRIO_AC 0 #define TRIO_AD 1 #define TRIO_BC 2 #define TRIO_BD 3 #define TRIO_CA 4 #define TRIO_DA 5 #define TRIO_CB 6 #define TRIO_DB 7 typedef struct _args_t { bcf_hdr_t *hdr; hmm_t *hmm; double *eprob, *tprob, pij, pgt_err; uint32_t *sites; int32_t *gt_arr; int nsites, msites, ngt_arr, prev_rid; int mode, nstates, nhet_father, nhet_mother; int imother,ifather,ichild, isample,jsample; void (*set_observed_prob) (bcf1_t *rec); char *prefix; FILE *fp; } args_t; static args_t args; #define SW_MOTHER 1 #define SW_FATHER 2 static int hap_switch[8][8]; static void set_observed_prob_trio(bcf1_t *rec); static void set_observed_prob_unrelated(bcf1_t *rec); static void init_hmm_trio(args_t *args); static void init_hmm_unrelated(args_t *args); const char *about(void) { return "Color shared chromosomal segments, requires phased GTs.\n"; } const char *usage(void) { return "\n" "About: Color shared chromosomal segments, requires phased GTs. The output\n" " can be visualized using the color-chrs.pl script.\n" "Usage: bcftools +color-chrs [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -p, --prefix output files prefix\n" " -t, --trio names of mother, father and the child\n" " -u, --unrelated names of two unrelated samples\n" "\n" "Example:\n" " bcftools +color-chrs in.vcf --\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { char *trio_samples = NULL, *unrelated_samples = NULL; memset(&args,0,sizeof(args_t)); args.prev_rid = -1; args.hdr = in; args.pij = 2e-8; args.pgt_err = 1e-9; static struct option loptions[] = { {"prefix",1,0,'p'}, {"trio",1,0,'t'}, {"unrelated",1,0,'u'}, {0,0,0,0} }; int c; while ((c = getopt_long(argc, argv, "?ht:u:p:",loptions,NULL)) >= 0) { switch (c) { case 'p': args.prefix = optarg; break; case 't': trio_samples = optarg; break; case 'u': unrelated_samples = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } if ( optind != argc ) error("%s",usage()); if ( trio_samples && unrelated_samples ) error("Expected only one of the -t/-u options\n"); if ( !trio_samples && !unrelated_samples ) error("Expected one of the -t/-u options\n"); if ( !args.prefix ) error("Expected the -p option\n"); int ret = bcf_hdr_set_samples(args.hdr, trio_samples ? trio_samples : unrelated_samples, 0); if ( ret<0 ) error("Could not parse samples: %s\n", trio_samples ? trio_samples : unrelated_samples); else if ( ret>0 ) error("%d-th sample not found: %s\n", ret,trio_samples ? trio_samples : unrelated_samples); if ( trio_samples ) { int i,n = 0; char **list = hts_readlist(trio_samples, 0, &n); if ( n!=3 ) error("Expected three sample names with -t\n"); args.imother = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[0]); args.ifather = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[1]); args.ichild = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[2]); for (i=0; instates = 8; args->tprob = (double*) malloc(sizeof(double)*args->nstates*args->nstates); for (i=0; instates; i++) for (j=0; jnstates; j++) hap_switch[i][j] = 0; hap_switch[TRIO_AD][TRIO_AC] = SW_FATHER; hap_switch[TRIO_BC][TRIO_AC] = SW_MOTHER; hap_switch[TRIO_BD][TRIO_AC] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_AC][TRIO_AD] = SW_FATHER; hap_switch[TRIO_BC][TRIO_AD] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_BD][TRIO_AD] = SW_MOTHER; hap_switch[TRIO_AC][TRIO_BC] = SW_MOTHER; hap_switch[TRIO_AD][TRIO_BC] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_BD][TRIO_BC] = SW_FATHER; hap_switch[TRIO_AC][TRIO_BD] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_AD][TRIO_BD] = SW_MOTHER; hap_switch[TRIO_BC][TRIO_BD] = SW_FATHER; hap_switch[TRIO_DA][TRIO_CA] = SW_FATHER; hap_switch[TRIO_CB][TRIO_CA] = SW_MOTHER; hap_switch[TRIO_DB][TRIO_CA] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_CA][TRIO_DA] = SW_FATHER; hap_switch[TRIO_CB][TRIO_DA] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_DB][TRIO_DA] = SW_MOTHER; hap_switch[TRIO_CA][TRIO_CB] = SW_MOTHER; hap_switch[TRIO_DA][TRIO_CB] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_DB][TRIO_CB] = SW_FATHER; hap_switch[TRIO_CA][TRIO_DB] = SW_MOTHER | SW_FATHER; hap_switch[TRIO_DA][TRIO_DB] = SW_MOTHER; hap_switch[TRIO_CB][TRIO_DB] = SW_FATHER; for (i=0; instates; i++) { for (j=0; jnstates; j++) { if ( !hap_switch[i][j] ) MAT(args->tprob,args->nstates,i,j) = 0; else { MAT(args->tprob,args->nstates,i,j) = 1; if ( hap_switch[i][j] & SW_MOTHER ) MAT(args->tprob,args->nstates,i,j) *= args->pij; if ( hap_switch[i][j] & SW_FATHER ) MAT(args->tprob,args->nstates,i,j) *= args->pij; } } } for (i=0; instates; i++) { double sum = 0; for (j=0; jnstates; j++) { if ( i!=j ) sum += MAT(args->tprob,args->nstates,i,j); } MAT(args->tprob,args->nstates,i,i) = 1 - sum; } #if 0 for (i=0; instates; i++) { for (j=0; jnstates; j++) fprintf(stderr,"\t%d",hap_switch[j][i]); fprintf(stderr,"\n"); } for (i=0; instates; i++) { for (j=0; jnstates; j++) fprintf(stderr,"\t%e",MAT(args->tprob,args->nstates,j,i)); fprintf(stderr,"\n"); } #endif args->hmm = hmm_init(args->nstates, args->tprob, 10000); } static void init_hmm_unrelated(args_t *args) { int i,j; args->nstates = 7; args->tprob = (double*) malloc(sizeof(double)*args->nstates*args->nstates); for (i=0; instates; i++) { for (j=0; jnstates; j++) MAT(args->tprob,args->nstates,i,j) = args->pij; } MAT(args->tprob,args->nstates,UNRL_0101,UNRL_xxxx) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_0110,UNRL_xxxx) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_x0x0,UNRL_0x0x) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_0110,UNRL_0x0x) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_x00x,UNRL_0xx0) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_0101,UNRL_0xx0) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_0101,UNRL_x00x) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_0110,UNRL_x0x0) = args->pij*args->pij; MAT(args->tprob,args->nstates,UNRL_0110,UNRL_0101) = args->pij*args->pij; for (i=0; instates; i++) { for (j=i+1; jnstates; j++) MAT(args->tprob,args->nstates,i,j) = MAT(args->tprob,args->nstates,j,i); } for (i=0; instates; i++) { double sum = 0; for (j=0; jnstates; j++) if ( i!=j ) sum += MAT(args->tprob,args->nstates,i,j); MAT(args->tprob,args->nstates,i,i) = 1 - sum; } #if 0 for (i=0; instates; i++) { for (j=0; jnstates; j++) fprintf(stderr,"\t%e",MAT(args->tprob,args->nstates,j,i)); fprintf(stderr,"\n"); } #endif args->hmm = hmm_init(args->nstates, args->tprob, 10000); } static inline double prob_shared(float af, int a, int b) { return a==b ? 1-args.pgt_err : args.pgt_err; } static inline double prob_not_shared(float af, int a, int b) { if ( a!=b ) return af*(1-af); else if ( a==0 ) return (1-af)*(1-af); else return af*af; } static void set_observed_prob_unrelated(bcf1_t *rec) { float af = 0.5; // alternate allele frequency int ngt = bcf_get_genotypes(args.hdr, rec, &args.gt_arr, &args.ngt_arr); if ( ngt<0 ) return; if ( ngt!=4 ) return; // chrX int32_t a,b,c,d; a = args.gt_arr[2*args.isample]; b = args.gt_arr[2*args.isample+1]; c = args.gt_arr[2*args.jsample]; d = args.gt_arr[2*args.jsample+1]; if ( bcf_gt_is_missing(a) || bcf_gt_is_missing(b) ) return; if ( bcf_gt_is_missing(c) || bcf_gt_is_missing(d) ) return; if ( !bcf_gt_is_phased(a) && !bcf_gt_is_phased(b) ) return; // only the second allele should be set when phased if ( !bcf_gt_is_phased(c) && !bcf_gt_is_phased(d) ) return; a = bcf_gt_allele(a); b = bcf_gt_allele(b); c = bcf_gt_allele(c); d = bcf_gt_allele(d); int m = args.msites; args.nsites++; hts_expand(uint32_t,args.nsites,args.msites,args.sites); if ( m!=args.msites ) args.eprob = (double*) realloc(args.eprob, sizeof(double)*args.msites*args.nstates); args.sites[args.nsites-1] = rec->pos; double *prob = args.eprob + args.nstates*(args.nsites-1); prob[UNRL_xxxx] = prob_not_shared(af,a,c) * prob_not_shared(af,a,d) * prob_not_shared(af,b,c) * prob_not_shared(af,b,d); prob[UNRL_0x0x] = prob_shared(af,a,c) * prob_not_shared(af,b,d); prob[UNRL_0xx0] = prob_shared(af,a,d) * prob_not_shared(af,b,c); prob[UNRL_x00x] = prob_shared(af,b,c) * prob_not_shared(af,a,d); prob[UNRL_x0x0] = prob_shared(af,b,d) * prob_not_shared(af,a,c); prob[UNRL_0101] = prob_shared(af,a,c) * prob_shared(af,b,d); prob[UNRL_0110] = prob_shared(af,a,d) * prob_shared(af,b,c); #if 0 static int x = 0; if ( !x++) { printf("p(0==0) .. %f\n", prob_shared(af,0,0)); printf("p(0!=0) .. %f\n", prob_not_shared(af,0,0)); printf("p(0==1) .. %f\n", prob_shared(af,0,1)); printf("p(0!=1) .. %f\n", prob_not_shared(af,0,1)); } printf("%d|%d %d|%d x:%f 11:%f 12:%f 21:%f 22:%f 11,22:%f 12,21:%f %d\n", a,b,c,d, prob[UNRL_xxxx], prob[UNRL_0x0x], prob[UNRL_0xx0], prob[UNRL_x00x], prob[UNRL_x0x0], prob[UNRL_0101], prob[UNRL_0110], rec->pos+1); #endif } static void set_observed_prob_trio(bcf1_t *rec) { int ngt = bcf_get_genotypes(args.hdr, rec, &args.gt_arr, &args.ngt_arr); if ( ngt<0 ) return; if ( ngt!=6 ) return; // chrX int32_t a,b,c,d,e,f; a = args.gt_arr[2*args.imother]; b = args.gt_arr[2*args.imother+1]; c = args.gt_arr[2*args.ifather]; d = args.gt_arr[2*args.ifather+1]; e = args.gt_arr[2*args.ichild]; f = args.gt_arr[2*args.ichild+1]; if ( bcf_gt_is_missing(a) || bcf_gt_is_missing(b) ) return; if ( bcf_gt_is_missing(c) || bcf_gt_is_missing(d) ) return; if ( bcf_gt_is_missing(e) || bcf_gt_is_missing(f) ) return; if ( !bcf_gt_is_phased(a) && !bcf_gt_is_phased(b) ) return; // only the second allele should be set when phased if ( !bcf_gt_is_phased(c) && !bcf_gt_is_phased(d) ) return; if ( !bcf_gt_is_phased(e) && !bcf_gt_is_phased(f) ) return; a = bcf_gt_allele(a); b = bcf_gt_allele(b); c = bcf_gt_allele(c); d = bcf_gt_allele(d); e = bcf_gt_allele(e); f = bcf_gt_allele(f); int mother = (1<pos; double *prob = args.eprob + args.nstates*(args.nsites-1); prob[TRIO_AC] = prob_shared(0,e,a) * prob_shared(0,f,c); prob[TRIO_AD] = prob_shared(0,e,a) * prob_shared(0,f,d); prob[TRIO_BC] = prob_shared(0,e,b) * prob_shared(0,f,c); prob[TRIO_BD] = prob_shared(0,e,b) * prob_shared(0,f,d); prob[TRIO_CA] = prob_shared(0,e,c) * prob_shared(0,f,a); prob[TRIO_DA] = prob_shared(0,e,d) * prob_shared(0,f,a); prob[TRIO_CB] = prob_shared(0,e,c) * prob_shared(0,f,b); prob[TRIO_DB] = prob_shared(0,e,d) * prob_shared(0,f,b); } void flush_viterbi(args_t *args) { const char *s1, *s2, *s3 = NULL; if ( args->mode==C_UNRL ) { s1 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->isample); s2 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->jsample); } else if ( args->mode==C_TRIO ) { s1 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->imother); s3 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->ifather); s2 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->ichild); } else abort(); if ( !args->fp ) { kstring_t str = {0,0,0}; kputs(args->prefix, &str); kputs(".dat", &str); args->fp = fopen(str.s,"w"); if ( !args->fp ) error("%s: %s\n", str.s,strerror(errno)); free(str.s); fprintf(args->fp,"# SG, shared segment\t[2]Chromosome\t[3]Start\t[4]End\t[5]%s:1\t[6]%s:2\n",s2,s2); fprintf(args->fp,"# SW, number of switches\t[3]Sample\t[4]Chromosome\t[5]nHets\t[5]nSwitches\t[6]switch rate\n"); } hmm_run_viterbi(args->hmm,args->nsites,args->eprob,args->sites); uint8_t *vpath = hmm_get_viterbi_path(args->hmm); int i, iprev = -1, prev_state = -1, nstates = hmm_get_nstates(args->hmm); int nswitch_mother = 0, nswitch_father = 0; for (i=0; insites; i++) { int state = vpath[i*nstates]; if ( state!=prev_state || i+1==args->nsites ) { uint32_t start = iprev>=0 ? args->sites[iprev]+1 : 1, end = i>0 ? args->sites[i-1] : 1; const char *chr = bcf_hdr_id2name(args->hdr,args->prev_rid); if ( args->mode==C_UNRL ) { switch (prev_state) { case UNRL_0x0x: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t-\n", chr,start,end,s1); break; case UNRL_0xx0: fprintf(args->fp,"SG\t%s\t%d\t%d\t-\t%s:1\n", chr,start,end,s1); break; case UNRL_x00x: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t-\n", chr,start,end,s1); break; case UNRL_x0x0: fprintf(args->fp,"SG\t%s\t%d\t%d\t-\t%s:2\n", chr,start,end,s1); break; case UNRL_0101: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:2\n", chr,start,end,s1,s1); break; case UNRL_0110: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:1\n", chr,start,end,s1,s1); break; } } else if ( args->mode==C_TRIO ) { switch (prev_state) { case TRIO_AC: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:1\n", chr,start,end,s1,s3); break; case TRIO_AD: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:2\n", chr,start,end,s1,s3); break; case TRIO_BC: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:1\n", chr,start,end,s1,s3); break; case TRIO_BD: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:2\n", chr,start,end,s1,s3); break; case TRIO_CA: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:1\n", chr,start,end,s3,s1); break; case TRIO_DA: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:1\n", chr,start,end,s3,s1); break; case TRIO_CB: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:2\n", chr,start,end,s3,s1); break; case TRIO_DB: fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:2\n", chr,start,end,s3,s1); break; } if ( hap_switch[state][prev_state] & SW_MOTHER ) nswitch_mother++; if ( hap_switch[state][prev_state] & SW_FATHER ) nswitch_father++; } iprev = i-1; } prev_state = state; } float mrate = args->nhet_mother>1 ? (float)nswitch_mother/(args->nhet_mother-1) : 0; float frate = args->nhet_father>1 ? (float)nswitch_father/(args->nhet_father-1) : 0; fprintf(args->fp,"SW\t%s\t%s\t%d\t%d\t%f\n", s1,bcf_hdr_id2name(args->hdr,args->prev_rid),args->nhet_mother,nswitch_mother,mrate); fprintf(args->fp,"SW\t%s\t%s\t%d\t%d\t%f\n", s3,bcf_hdr_id2name(args->hdr,args->prev_rid),args->nhet_father,nswitch_father,frate); args->nsites = 0; args->nhet_father = args->nhet_mother = 0; } bcf1_t *process(bcf1_t *rec) { if ( args.prev_rid==-1 ) args.prev_rid = rec->rid; if ( args.prev_rid!=rec->rid ) flush_viterbi(&args); args.prev_rid = rec->rid; args.set_observed_prob(rec); return NULL; } void destroy(void) { flush_viterbi(&args); fclose(args.fp); free(args.gt_arr); free(args.tprob); free(args.sites); free(args.eprob); hmm_destroy(args.hmm); } bcftools-1.21/plugins/color-chrs.mk000066400000000000000000000003121467060157400173430ustar00rootroot00000000000000plugins/color-chrs.so: plugins/color-chrs.c version.h version.c HMM.h HMM.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ HMM.c version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/contrast.c000066400000000000000000000603371467060157400167550ustar00rootroot00000000000000/* The MIT License Copyright (c) 2018-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include // for isatty #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define PRINT_PASSOC (1<<0) #define PRINT_FASSOC (1<<1) #define PRINT_NASSOC (1<<2) #define PRINT_NOVELAL (1<<3) #define PRINT_NOVELGT (1<<4) typedef struct { int argc, filter_logic, regions_is_file, targets_is_file, output_type, force_samples, clevel; int regions_overlap, targets_overlap; uint32_t annots; char **argv, *output_fname, *fname, *regions, *targets, *filter_str, *annots_str; char *control_samples_str, *case_samples_str, *max_AC_str; int *control_smpl, *case_smpl, ncontrol_smpl, ncase_smpl; filter_t *filter; bcf_srs_t *sr; bcf_hdr_t *hdr, *hdr_out; htsFile *out_fh; int32_t *gts; int mgts; uint32_t *control_gts; int ncontrol_gts, mcontrol_gts, ntotal, nskipped, ntested, ncase_al, ncase_gt; kstring_t case_als_smpl, case_gts_smpl; int max_AC, nals[4]; // nals: number of control-ref, control-alt, case-ref and case-alt alleles in the region char *index_fn; int write_index; } args_t; args_t args; const char *about(void) { return "Find novel alleles and genotypes in two groups of samples.\n"; } static const char *usage_text(void) { return "\n" "About: Runs a basic association test, per-site or in a region, and checks for novel alleles and\n" " genotypes in two groups of samples. Adds the following INFO annotations:\n" " - PASSOC .. Fisher's exact test probability of genotypic association (REF vs non-REF allele)\n" " - FASSOC .. proportion of non-REF allele in controls and cases\n" " - NASSOC .. number of control-ref, control-alt, case-ref and case-alt alleles\n" " - NOVELAL .. lists samples with a novel allele not observed in the control group\n" " - NOVELGT .. lists samples with a novel genotype not observed in the control group\n" "Usage: bcftools +contrast [Plugin Options]\n" "Plugin options:\n" " -a, --annots LIST List of annotations to output [PASSOC,FASSOC,NOVELAL]\n" " -0, --control-samples LIST|FILE File or comma-separated list of control (background) samples\n" " -1, --case-samples LIST|FILE File or comma-separated list of samples where novel allele or genotype is expected\n" " -e, --exclude EXPR Exclude sites and samples for which the expression is true\n" " -f, --max-allele-freq NUM Calculate enrichment of rare alleles. Floating point numbers between 0 and 1 are\n" " interpreted as ALT allele frequencies, integers as ALT allele counts\n" " --force-samples Continue even if some samples listed in the -0,-1 files are missing from the VCF\n" " -i, --include EXPR Include sites and samples for which the expression is true\n" " -o, --output FILE Output file name [stdout]\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -r, --regions REG Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -t, --targets REG Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "Example:\n" " # Test if any of the samples a,b is different from the samples c,d,e\n" " bcftools +contrast -0 c,d,e -1 a,b file.bcf\n" "\n" " # Same as above, but read samples from a file. In case of a name collision, the sample name\n" " # has precedence: the existence of a file with a list of samples is not checked unless no such\n" " # sample exists in the VCF. Use a full path (e.g. \"./string\" instead of \"string\") to avoid\n" " # name clashes\n" " bcftools +contrast -0 samples0.txt -1 samples1.txt file.bcf\n" "\n" " # The same as above but checks for enrichment of rare alleles, AF<0.001 in this example, in a region\n" " bcftools +contrast -r 20:1000-2000 -f 0.001 -0 samples0.txt -1 samples1.txt file.bcf\n" "\n"; } static int cmp_int(const void *a, const void *b) { if ( *((int*)a) < *((int*)b) ) return -1; if ( *((int*)a) > *((int*)b) ) return -1; return 0; } static void read_sample_list_or_file(bcf_hdr_t *hdr, const char *str, int **smpl, int *nsmpl, int force_samples) { char **str_list = NULL; int i,j, *list = NULL, nlist = 0, is_file, nskipped = 0; for (is_file=0; is_file<=1; is_file++) { if ( str_list ) { for (i=0; i= 0 ) continue; if ( is_file ) { if ( !force_samples ) error("The sample \"%s\" is not present in the VCF. Use --force-samples to proceed anyway.\n", str_list[i]); j--; nskipped++; continue; } break; } if ( i==nlist ) break; } for (i=0; i1?"s":"",nskipped,str,nskipped>1?"are":"is"); free(str_list); qsort(list,nlist,sizeof(*list),cmp_int); *smpl = list; *nsmpl = nlist; } static void init_data(args_t *args) { int ntmp, i; char **tmp = hts_readlist(args->annots_str, 0, &ntmp); for (i=0; iannots |= PRINT_PASSOC; else if ( !strcasecmp("FASSOC",tmp[i]) ) args->annots |= PRINT_FASSOC; else if ( !strcasecmp("NASSOC",tmp[i]) ) args->annots |= PRINT_NASSOC; else if ( !strcasecmp("NOVELAL",tmp[i]) ) args->annots |= PRINT_NOVELAL; else if ( !strcasecmp("NOVELGT",tmp[i]) ) args->annots |= PRINT_NOVELGT; else error("The annotation is not recognised: %s\n", tmp[i]); free(tmp[i]); } free(tmp); args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; bcf_sr_set_opt(args->sr,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets ) { bcf_sr_set_opt(args->sr,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); } if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); args->hdr_out = bcf_hdr_dup(args->hdr); if ( args->annots & PRINT_PASSOC ) bcf_hdr_append(args->hdr_out, "##INFO="); if ( args->annots & PRINT_FASSOC ) bcf_hdr_append(args->hdr_out, "##INFO="); if ( args->annots & PRINT_NASSOC ) bcf_hdr_append(args->hdr_out, "##INFO="); if ( args->annots & PRINT_NOVELAL ) bcf_hdr_append(args->hdr_out, "##INFO="); if ( args->annots & PRINT_NOVELGT ) bcf_hdr_append(args->hdr_out, "##INFO="); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); read_sample_list_or_file(args->hdr, args->control_samples_str, &args->control_smpl, &args->ncontrol_smpl, args->force_samples); read_sample_list_or_file(args->hdr, args->case_samples_str, &args->case_smpl, &args->ncase_smpl, args->force_samples); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( bcf_hdr_write(args->out_fh, args->hdr_out)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr_out,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); if ( args->max_AC_str ) { char *tmp; args->max_AC = strtol(args->max_AC_str, &tmp, 10); if ( tmp==args->max_AC_str || *tmp ) { double val = strtod(args->max_AC_str, &tmp); if ( tmp==args->max_AC_str || *tmp ) error("Could not parse the argument: -f, --max-allele-freq %s\n", args->max_AC_str); if ( val<0 || val>1 ) error("Expected integer or float from the range [0,1]: -f, --max-allele-freq %s\n", args->max_AC_str); args->max_AC = val * bcf_hdr_nsamples(args->hdr); if ( !args->max_AC ) args->max_AC = 1; } } } static void destroy_data(args_t *args) { bcf_hdr_destroy(args->hdr_out); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); free(args->case_als_smpl.s); free(args->case_gts_smpl.s); free(args->gts); free(args->control_gts); free(args->control_smpl); free(args->case_smpl); if ( args->filter ) filter_destroy(args->filter); bcf_sr_destroy(args->sr); free(args); } static inline int binary_search(uint32_t val, uint32_t *dat, int ndat) { int i = -1, imin = 0, imax = ndat - 1; while ( imin<=imax ) { i = (imin+imax)/2; if ( dat[i] < val ) imin = i + 1; else if ( dat[i] > val ) imax = i - 1; else return 1; } return 0; } static inline void binary_insert(uint32_t val, uint32_t **dat, int *ndat, int *mdat) { int i = -1, imin = 0, imax = *ndat - 1; while ( imin<=imax ) { i = (imin+imax)/2; if ( (*dat)[i] < val ) imin = i + 1; else if ( (*dat)[i] > val ) imax = i - 1; else return; } while ( i>=0 && (*dat)[i]>val ) i--; (*ndat)++; hts_expand(uint32_t, (*ndat), (*mdat), (*dat)); if ( *ndat > 1 ) memmove(*dat + i + 1, *dat + i, sizeof(uint32_t)*(*ndat - i - 1)); (*dat)[i+1] = val; } static int process_record(args_t *args, bcf1_t *rec) { args->ntotal++; static int warned = 0; int ngts = bcf_get_genotypes(args->hdr, rec, &args->gts, &args->mgts); ngts /= rec->n_sample; if ( ngts>2 ) error("todo: ploidy=%d\n", ngts); args->ncontrol_gts = 0; uint32_t control_als = 0; int32_t nals[4] = {0,0,0,0}; // ctrl-ref, ctrl-alt, case-ref, case-alt int i,j; for (i=0; incontrol_smpl; i++) { uint32_t gt = 0; int32_t *ptr = args->gts + args->control_smpl[i]*ngts; for (j=0; j 31 ) { if ( !warned ) { fprintf(stderr,"Too many alleles (>32) at %s:%"PRId64", skipping the site.\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); warned = 1; } args->nskipped++; return -1; } control_als |= 1<annots & PRINT_NOVELGT ) binary_insert(gt, &args->control_gts, &args->ncontrol_gts, &args->mcontrol_gts); } if ( !control_als && args->ncontrol_smpl ) { // all are missing args->nskipped++; return -1; } args->case_als_smpl.l = 0; args->case_gts_smpl.l = 0; int has_gt = 0; for (i=0; incase_smpl; i++) { int case_al = 0; uint32_t gt = 0; int32_t *ptr = args->gts + args->case_smpl[i]*ngts; for (j=0; j 31 ) { if ( !warned ) { fprintf(stderr,"Too many alleles (>32) at %s:%"PRId64", skipping. (todo?)\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); warned = 1; } args->nskipped++; return -1; } if ( !(control_als & (1<hdr->samples[ args->case_smpl[i] ]; if ( case_al && (args->annots & PRINT_NOVELAL) ) { if ( args->case_als_smpl.l ) kputc(',', &args->case_als_smpl); kputs(smpl, &args->case_als_smpl); } else if ( (args->annots & PRINT_NOVELGT) && !binary_search(gt, args->control_gts, args->ncontrol_gts) ) { if ( args->case_gts_smpl.l ) kputc(',', &args->case_gts_smpl); kputs(smpl, &args->case_gts_smpl); } } if ( !has_gt && args->ncase_smpl ) { // all are missing args->nskipped++; return -1; } if ( args->max_AC ) { if ( nals[0]+nals[2] > nals[1]+nals[3] ) { if ( nals[1]+nals[3] <= args->max_AC ) for (i=0; i<4; i++) args->nals[i] += nals[i]; } else { if ( nals[0]+nals[2] <= args->max_AC ) { args->nals[0] += nals[1]; args->nals[1] += nals[0]; args->nals[2] += nals[3]; args->nals[3] += nals[2]; } } } float vals[2]; if ( (args->annots & PRINT_PASSOC) && args->ncontrol_smpl && args->ncase_smpl ) { double left, right, fisher; kt_fisher_exact(nals[0],nals[1],nals[2],nals[3], &left,&right,&fisher); vals[0] = fisher; bcf_update_info_float(args->hdr_out, rec, "PASSOC", vals, 1); } if ( (args->annots & PRINT_FASSOC) && args->ncontrol_smpl && args->ncase_smpl ) { if ( nals[0]+nals[1] ) vals[0] = (float)nals[1]/(nals[0]+nals[1]); else bcf_float_set_missing(vals[0]); if ( nals[2]+nals[3] ) vals[1] = (float)nals[3]/(nals[2]+nals[3]); else bcf_float_set_missing(vals[1]); bcf_update_info_float(args->hdr_out, rec, "FASSOC", vals, 2); } if ( args->annots & PRINT_NASSOC ) bcf_update_info_int32(args->hdr_out, rec, "NASSOC", nals, 4); if ( args->case_als_smpl.l ) { bcf_update_info_string(args->hdr_out, rec, "NOVELAL", args->case_als_smpl.s); args->ncase_al++; } if ( args->case_gts_smpl.l ) { bcf_update_info_string(args->hdr_out, rec, "NOVELGT", args->case_gts_smpl.s); args->ncase_gt++; } args->ntested++; return 0; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->annots_str = "PASSOC,FASSOC"; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"max-allele-freq",required_argument,0,'f'}, {"annots",required_argument,0,'a'}, {"force-samples",no_argument,0,1}, {"bg-samples",required_argument,0,'0'}, // renamed to --control-samples, leaving it in for backward compatibility {"control-samples",required_argument,0,'0'}, {"novel-samples",required_argument,0,'1'}, // renamed to --case-samples, leaving it in for backward compatibility {"case-samples",required_argument,0,'1'}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,3}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,4}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "O:o:i:e:r:R:t:T:0:1:a:f:W::",loptions,NULL)) >= 0) { switch (c) { case 1 : args->force_samples = 1; break; case 'f': args->max_AC_str = optarg; break; case 'a': args->annots_str = optarg; break; case '0': args->control_samples_str = optarg; break; case '1': args->case_samples_str = optarg; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 3 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else args->fname = argv[optind]; if ( !args->control_samples_str ) error("Error: missing the -0, --control-samples option\n"); if ( !args->case_samples_str ) error("Error: missing the -1, --case-samples option\n"); init_data(args); while ( bcf_sr_next_line(args->sr) ) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( args->filter ) { int pass = filter_test(args->filter, rec, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) continue; } process_record(args, rec); if ( bcf_write(args->out_fh, args->hdr_out, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } fprintf(stderr,"Total/processed/skipped/case_allele/case_gt:\t%d\t%d\t%d\t%d\t%d\n", args->ntotal, args->ntested, args->nskipped, args->ncase_al, args->ncase_gt); if ( args->max_AC ) { double val1, val2, fisher; kt_fisher_exact(args->nals[0],args->nals[1],args->nals[2],args->nals[3], &val1,&val2,&fisher); val1 = args->nals[0]+args->nals[1] ? (float)args->nals[1]/(args->nals[0]+args->nals[1]) : 0; val2 = args->nals[2]+args->nals[3] ? (float)args->nals[3]/(args->nals[2]+args->nals[3]) : 0; fprintf(stderr,"max_AC/PASSOC/FASSOC/NASSOC:\t%d\t%e\t%f,%f\t%d,%d,%d,%d\n",args->max_AC,fisher,val1,val2,args->nals[0],args->nals[1],args->nals[2],args->nals[3]); } destroy_data(args); return 0; } bcftools-1.21/plugins/counts.c000066400000000000000000000051011467060157400164170ustar00rootroot00000000000000/* plugins/counts.c -- counts SNPs, Indels, and total number of sites. Copyright (C) 2013-2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include uint64_t nsamples, nsnps, nindels, nmnps, nothers, nsites; /* This short description is used to generate the output of `bcftools plugin -l`. */ const char *about(void) { return "A minimal plugin which counts number of samples, SNPs,\n" "INDELs, MNPs and total number of sites.\n"; } /* Called once at startup, it initializes local variables. Return 1 to suppress VCF/BCF header from printing, 0 otherwise. */ int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { nsamples = bcf_hdr_nsamples(in); nsnps = nindels = nmnps = nothers = nsites = 0; return 1; } /* Called for each VCF record. Return rec to output the line or NULL to suppress output. */ bcf1_t *process(bcf1_t *rec) { int type = bcf_get_variant_types(rec); if ( type & VCF_SNP ) nsnps++; if ( type & VCF_INDEL ) nindels++; if ( type & VCF_MNP ) nmnps++; if ( type & VCF_OTHER ) nothers++; nsites++; return NULL; } /* Clean up. */ void destroy(void) { printf("Number of samples: %"PRIu64"\n", nsamples); printf("Number of SNPs: %"PRIu64"\n", nsnps); printf("Number of INDELs: %"PRIu64"\n", nindels); printf("Number of MNPs: %"PRIu64"\n", nmnps); printf("Number of others: %"PRIu64"\n", nothers); printf("Number of sites: %"PRIu64"\n", nsites); } bcftools-1.21/plugins/dosage.c000066400000000000000000000243241467060157400163560ustar00rootroot00000000000000/* plugins/dosage.c -- prints genotype dosage. Copyright (C) 2014-2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "bcftools.h" /* This short description is used to generate the output of `bcftools plugin -l`. */ const char *about(void) { return "Prints genotype dosage determined from tags requested by the user.\n"; } const char *usage(void) { return "\n" "About: Print genotype dosage\n" "Usage: bcftools +dosage [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -t, --tags VCF tags to determine the dosage from [PL,GL,GT]\n" "\n" "Example:\n" " bcftools +dosage in.vcf -- -t GT\n" "\n"; } bcf_hdr_t *in_hdr = NULL; int pl_type = 0, gl_type = 0; uint8_t *buf = NULL; int nbuf = 0; // NB: number of elements, not bytes char **tags = NULL; int ntags = 0; float *vals = NULL, *dsg = NULL; int mvals, mdsg; typedef int (*dosage_f) (bcf1_t *); dosage_f *handlers = NULL; int nhandlers = 0; int calc_dosage_PL(bcf1_t *rec) { int i, j, nret = bcf_get_format_values(in_hdr,rec,"PL",(void**)&buf,&nbuf,pl_type); if ( nret<0 ) return -1; nret /= rec->n_sample; if ( nret != rec->n_allele*(rec->n_allele+1)/2 ) return -1; // not diploid hts_expand(float, nret, mvals, vals); hts_expand(float, rec->n_allele, mdsg, dsg); #define BRANCH(type_t,is_missing,is_vector_end) \ { \ type_t *ptr = (type_t*) buf; \ for (i=0; in_sample; i++) \ { \ float sum = 0; \ for (j=0; jn_allele; j++) dsg[j] = -1; \ else \ { \ if ( sum ) for (j=0; jn_allele); \ int k, l = 0; \ for (j=0; jn_allele; j++) \ { \ for (k=0; k<=j; k++) \ { \ dsg[j] += vals[l]; \ dsg[k] += vals[l]; \ l++; \ } \ } \ } \ for (j=1; jn_allele; j++) \ printf("%c%f",j==1?'\t':',',dsg[j]); \ ptr += nret; \ } \ } switch (pl_type) { case BCF_HT_INT: BRANCH(int32_t,ptr[j]==bcf_int32_missing,ptr[j]==bcf_int32_vector_end); break; case BCF_HT_REAL: BRANCH(float,bcf_float_is_missing(ptr[j]),bcf_float_is_vector_end(ptr[j])); break; } #undef BRANCH return 0; } int calc_dosage_GL(bcf1_t *rec) { int i, j, nret = bcf_get_format_values(in_hdr,rec,"GL",(void**)&buf,&nbuf,gl_type); if ( nret<0 ) return -1; nret /= rec->n_sample; if ( nret != rec->n_allele*(rec->n_allele+1)/2 ) return -1; // not diploid hts_expand(float, nret, mvals, vals); hts_expand(float, rec->n_allele, mdsg, dsg); #define BRANCH(type_t,is_missing,is_vector_end) \ { \ type_t *ptr = (type_t*) buf; \ for (i=0; in_sample; i++) \ { \ float sum = 0; \ for (j=0; jn_allele; j++) dsg[j] = -1; \ else \ { \ if ( sum ) for (j=0; jn_allele); \ int k, l = 0; \ for (j=0; jn_allele; j++) \ { \ for (k=0; k<=j; k++) \ { \ dsg[j] += vals[l]; \ dsg[k] += vals[l]; \ l++; \ } \ } \ } \ for (j=1; jn_allele; j++) \ printf("%c%f",j==1?'\t':',',dsg[j]); \ ptr += nret; \ } \ } switch (gl_type) { case BCF_HT_INT: BRANCH(int32_t,ptr[j]==bcf_int32_missing,ptr[j]==bcf_int32_vector_end); break; case BCF_HT_REAL: BRANCH(float,bcf_float_is_missing(ptr[j]),bcf_float_is_vector_end(ptr[j])); break; } #undef BRANCH return 0; } int calc_dosage_GT(bcf1_t *rec) { int i, j, nret = bcf_get_genotypes(in_hdr,rec,(void**)&buf,&nbuf); if ( nret<0 ) return -1; nret /= rec->n_sample; int32_t *ptr = (int32_t*) buf; hts_expand(float, rec->n_allele, mdsg, dsg); for (i=0; in_sample; i++) { memset(dsg, 0, sizeof(float)*rec->n_allele); for (j=0; j rec->n_allele ) error("The allele index is out of range at %s:%"PRId64"\n", bcf_seqname(in_hdr,rec),(int64_t) rec->pos+1); dsg[idx] += 1; } if ( !j ) for (j=0; jn_allele; j++) dsg[j] = -1; for (j=1; jn_allele; j++) printf("%c%.1f",j==1?'\t':',',dsg[j]); ptr += nret; } return 0; } char **split_list(char *str, int *nitems) { int n = 0, done = 0; char *ss = strdup(str), **out = NULL; while ( !done && *ss ) { char *se = ss; while ( *se && *se!=',' ) se++; if ( !*se ) done = 1; *se = 0; n++; out = (char**) realloc(out,sizeof(char*)*n); out[n-1] = ss; ss = se+1; } *nitems = n; return out; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { int i, id, c; char *tags_str = "PL,GL,GT"; static struct option loptions[] = { {"tags",1,0,'t'}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "t:?h",loptions,NULL)) >= 0) { switch (c) { case 't': tags_str = optarg; break; case 'h': case '?': default: fprintf(stderr,"%s", usage()); exit(1); break; } } tags = split_list(tags_str, &ntags); in_hdr = in; for (i=0; isamples[i]); printf("\n"); return 1; } bcf1_t *process(bcf1_t *rec) { int i,j, ret; printf("%s\t%"PRId64"\t%s", bcf_seqname(in_hdr,rec),(int64_t) rec->pos+1,rec->d.allele[0]); if ( rec->n_allele == 1 ) printf("\t."); else for (i=1; in_allele; i++) printf("%c%s", i==1?'\t':',', rec->d.allele[i]); if ( rec->n_allele==1 ) { for (j=0; jn_sample; j++) printf("\t0.0"); } else { for (i=0; in_sample; i++) printf("\t-1.0"); } } printf("\n"); return NULL; } void destroy(void) { free(vals); free(dsg); free(handlers); free(buf); } bcftools-1.21/plugins/fill-AN-AC.c000066400000000000000000000043241467060157400166150ustar00rootroot00000000000000/* plugins/fill-AN-AC.c -- fills AN and AC INFO fields. Copyright (C) 2014 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include bcf_hdr_t *in_hdr, *out_hdr; int *arr = NULL, marr = 0; const char *about(void) { return "Fill INFO fields AN and AC. This plugin is DEPRECATED, use fill-tags instead.\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { in_hdr = in; out_hdr = out; bcf_hdr_append(out_hdr, "##INFO="); bcf_hdr_append(out_hdr, "##INFO="); return 0; } bcf1_t *process(bcf1_t *rec) { hts_expand(int,rec->n_allele,marr,arr); int ret = bcf_calc_ac(in_hdr,rec,arr,BCF_UN_FMT); if ( ret>0 ) { int i, an = 0; for (i=0; in_allele; i++) an += arr[i]; bcf_update_info_int32(out_hdr, rec, "AN", &an, 1); bcf_update_info_int32(out_hdr, rec, "AC", arr+1, rec->n_allele-1); } return rec; } void destroy(void) { free(arr); } bcftools-1.21/plugins/fill-from-fasta.c000066400000000000000000000174461467060157400201060ustar00rootroot00000000000000/* plugin/fill-from-fasta.c -- fill-from-fasta plugin. Copyright (C) 2016-2021 Genome Research Ltd. Author: Shane McCarthy Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include "filter.h" #include "bcftools.h" const char *about(void) { return "Fill INFO or REF field based on values in a fasta file\n"; } const char *usage(void) { return "\n" "About: Fill INFO or REF field based on values in a fasta file.\n" " The fasta file must be indexed with samtools faidx.\n" "Usage: bcftools +fill-from-fasta [General Options] -- [Plugin Options]\n" "\n" "General options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -c, --column REF or INFO tag, e.g. AA for ancestral allele\n" " -f, --fasta fasta file\n" " -h, --header-lines optional file containing header lines to append\n" " -i, --include annotate only records passing filter expression\n" " -e, --exclude annotate only records failing filter expression\n" " -N, --replace-non-ACGTN replace non-ACGTN characters with N\n" "\n" "Examples:\n" " # fill ancestral allele as INFO/AA for SNP records\n" " echo '##INFO=' > aa.hdr\n" " bcftools +fill-from-fasta in.vcf -- -c AA -f aa.fasta -h aa.hdr -i 'TYPE=\"snp\"'\n" "\n" " # fix the REF allele in VCFs where REF=N or other\n" " bcftools +fill-from-fasta in.vcf -- -c REF -f reference.fasta\n" "\n" " # select sites marked as P (PASS) in the 1000G Phase3 mask\n" " echo '##INFO=' > mask.hdr\n" " bcftools +fill-from-fasta in.vcf -Ou -- -c P3_MASK -f 1000G_mask.fasta -h mask.hdr | bcftools view -i 'P3_MASK=\"P\"'\n" "\n"; } bcf_hdr_t *in_hdr = NULL, *out_hdr = NULL; faidx_t *faidx; int anno = 0; char *column = NULL; int replace_nonACGTN = 0; #define ANNO_REF 1 #define ANNO_STRING 2 #define ANNO_INT 3 filter_t *filter; char *filter_str; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { int c; char *ref_fname = NULL, *header_fname = NULL; static struct option loptions[] = { {"replace-non-ACGTN",no_argument,NULL,'N'}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"column",required_argument,NULL,'c'}, {"fasta",required_argument,NULL,'f'}, {"header-lines",required_argument,NULL,'h'}, {NULL,0,NULL,0} }; while ((c = getopt_long(argc, argv, "c:f:?h:i:e:N",loptions,NULL)) >= 0) { switch (c) { case 'e': if ( filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); filter_str = optarg; filter_logic |= FLT_EXCLUDE; break; case 'i': if ( filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); filter_str = optarg; filter_logic |= FLT_INCLUDE; break; case 'N': replace_nonACGTN = 1; break; case 'c': column = optarg; break; case 'f': ref_fname = optarg; break; case 'h': header_fname = optarg; break; case '?': default: fprintf(stderr,"%s", usage()); exit(1); break; } } in_hdr = in; out_hdr = out; if ( filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) { fprintf(stderr,"Only one of -i or -e can be given.\n"); return -1; } if ( !column ) { fprintf(stderr,"--column option is required.\n"); return -1; } if (header_fname) { htsFile *file = hts_open(header_fname, "rb"); if ( !file ) { fprintf(stderr,"Error reading %s\n", header_fname); return -1; } kstring_t str = {0,0,0}; while ( hts_getline(file, KS_SEP_LINE, &str) > 0 ) { if ( bcf_hdr_append(out_hdr, str.s) ) { fprintf(stderr,"Could not parse %s: %s\n", header_fname, str.s); return -1; } } hts_close(file); free(str.s); if (bcf_hdr_sync(out_hdr) < 0) error_errno("[%s] Failed to update header", __func__); } if (!strcasecmp("REF", column)) anno = ANNO_REF; else { if ( !strncasecmp(column,"INFO/",5) ) column += 5; int hdr_id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, column); if (hdr_id<0) { fprintf(stderr,"No header ID found for %s. Header lines can be added with the --header-lines option\n", column); return -1; } switch ( bcf_hdr_id2type(out_hdr,BCF_HL_INFO,hdr_id) ) { case BCF_HT_INT: anno=ANNO_INT; break; case BCF_HT_STR: anno=ANNO_STRING; break; default: fprintf(stderr,"The type of %s not recognised (%d)\n", column, bcf_hdr_id2type(out_hdr,BCF_HL_INFO,hdr_id)); return -1; } } if ( !ref_fname ) { fprintf(stderr,"No fasta given.\n"); return -1; } faidx = fai_load(ref_fname); if ( filter_str ) filter = filter_init(in, filter_str); return 0; } bcf1_t *process(bcf1_t *rec) { // filter determines if we will annotate the record // return record unchanged if filter applied if ( filter ) { int ret = filter_test(filter, rec, NULL); if ( filter_logic==FLT_INCLUDE ) { if ( !ret ) return rec; } else if ( ret ) return rec; } int i; char *ref = rec->d.allele[0]; int ref_len = strlen(ref); int fa_len; // could be sped up here by fetching the whole chromosome? could assume // sorted, but revert to this when non-sorted records found? char *fa = faidx_fetch_seq(faidx, bcf_seqname(in_hdr,rec), rec->pos, rec->pos+ref_len-1, &fa_len); if ( !fa ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", bcf_hdr_id2name(in_hdr,rec->rid),(int64_t) rec->pos+1); for (i=0; i96 ) fa[i] -= 32; if ( replace_nonACGTN && fa[i]!='A' && fa[i]!='C' && fa[i]!='G' && fa[i]!='T' && fa[i]!='N' ) fa[i] = 'N'; } assert(ref_len == fa_len); if (anno==ANNO_REF) strncpy(rec->d.allele[0], fa, fa_len); else if (anno==ANNO_STRING) bcf_update_info_string(out_hdr, rec, column, fa); else if (anno==ANNO_INT && ref_len==1) { int val = atoi(&fa[0]); bcf_update_info_int32(out_hdr, rec, column, &val, 1); } free(fa); return rec; } void destroy(void) { fai_destroy(faidx); if (filter) filter_destroy(filter); } bcftools-1.21/plugins/fill-from-fasta.mk000066400000000000000000000003541467060157400202610ustar00rootroot00000000000000plugins/fill-from-fasta.so: plugins/fill-from-fasta.c version.h version.c filter.h filter.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(PERL_CFLAGS) $(LDFLAGS) -o $@ filter.c version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/fill-tags.c000066400000000000000000001255041467060157400170000ustar00rootroot00000000000000/* The MIT License Copyright (c) 2015-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #define SET_AN (1<<0) #define SET_AC (1<<1) #define SET_AC_Hom (1<<2) #define SET_AC_Het (1<<3) #define SET_AC_Hemi (1<<4) #define SET_AF (1<<5) #define SET_NS (1<<6) #define SET_MAF (1<<7) #define SET_HWE (1<<8) #define SET_ExcHet (1<<9) #define SET_FUNC (1<<10) #define SET_END (1<<11) #define SET_TYPE (1<<12) #define SET_VAF (1<<13) #define SET_VAF1 (1<<14) typedef struct _args_t args_t; typedef struct _ftf_t ftf_t; typedef struct _pop_t pop_t; typedef int (*fill_tag_f)(args_t *, bcf1_t *, pop_t *, ftf_t *); struct _ftf_t { char *src_tag, *dst_tag; fill_tag_f func; float *fval; int32_t *ival; int nfval, nival; int type, len, cnt; // VCF type (e.g. BCF_HT_REAL); length (BCF_VL_FIXED); count (e.g. 1) int info; // filling INFO or FORMAT? filter_t *filter; }; typedef struct { int nhom, nhet, nhemi, nac; } counts_t; struct _pop_t { int ns; int ncounts, mcounts; counts_t *counts; char *name, *suffix; int nsmpl, *smpl; ftf_t *ftf; int nftf; }; struct _args_t { bcf_hdr_t *in_hdr, *out_hdr; uint32_t tags, warned; int npop, drop_missing, gt_id; pop_t *pop, **smpl2pop; float *farr; int32_t *iarr, niarr, miarr, nfarr, mfarr, unpack; double *hwe_probs; int mhwe_probs; kstring_t str; kbitset_t *bset; }; static args_t *args; const char *about(void) { return "Set INFO tags AF, AC, AC_Hemi, AC_Hom, AC_Het, AN, ExcHet, HWE, MAF, NS; FORMAT/VAF and more.\n"; } const char *usage(void) { return "\n" "About: Set INFO tags AF, AC, AC_Hemi, AC_Hom, AC_Het, AN, ExcHet, HWE, MAF, NS\n" " FORMAT tag VAF, custom INFO/TAG=func(FMT/TAG).\n" " See examples below, run with -l for detailed description.\n" "Usage: bcftools +fill-tags [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -d, --drop-missing do not count half-missing genotypes \"./1\" as hemizygous\n" " -l, --list-tags list available tags with description\n" " -t, --tags LIST list of output tags, \"all\" for all tags\n" " -S, --samples-file FILE list of samples (first column) and comma-separated list of populations (second column)\n" "\n" "Example:\n" " # Print a detailed list of available tags\n" " bcftools +fill-tags -- -l\n" "\n" " # Fill INFO/AN and INFO/AC\n" " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -t AN,AC\n" "\n" " # Fill (almost) all available tags\n" " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -t all\n" "\n" " # Calculate HWE for sample groups (possibly multiple) read from a file\n" " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -S sample-group.txt -t HWE\n" "\n" " # Calculate total read depth (INFO/DP) from per-sample depths (FORMAT/DP)\n" " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -t 'DP:1=int(sum(FORMAT/DP))'\n" "\n" " # Calculate per-sample read depth (FORMAT/DP) from per-sample allelic depths (FORMAT/AD)\n" " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -t 'FORMAT/DP:1=int(smpl_sum(FORMAT/AD))'\n" "\n" " # Annotate with allelic fraction\n" " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -t FORMAT/VAF\n" "\n"; } void parse_samples(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); void *pop2i = khash_str2int_init(); void *smpli = khash_str2int_init(); kstring_t str = {0,0,0}; int moff = 0, *off = NULL, nsmpl = 0; while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ) { // NA12400 GRP1 // NA18507 GRP1,GRP2 char *pop_names = str.s + str.l - 1; while ( pop_names >= str.s && isspace(*pop_names) ) pop_names--; if ( pop_names <= str.s ) error("Could not parse the file: %s\n", str.s); pop_names[1] = 0; // trailing spaces while ( pop_names >= str.s && !isspace(*pop_names) ) pop_names--; if ( pop_names <= str.s ) error("Could not parse the file: %s\n", str.s); char *smpl = pop_names++; while ( smpl >= str.s && isspace(*smpl) ) smpl--; if ( smpl <= str.s+1 ) error("Could not parse the file: %s\n", str.s); smpl[1] = 0; smpl = str.s; int ismpl = bcf_hdr_id2int(args->in_hdr,BCF_DT_SAMPLE,smpl); if ( ismpl<0 ) { fprintf(stderr,"Warning: The sample not present in the VCF: %s\n",smpl); continue; } if ( khash_str2int_has_key(smpli,smpl) ) { fprintf(stderr,"Warning: The sample is listed twice in %s: %s\n",fname,smpl); continue; } khash_str2int_inc(smpli,strdup(smpl)); int i,npops = ksplit_core(pop_names,',',&moff,&off); for (i=0; inpop); args->npop++; args->pop = (pop_t*) realloc(args->pop,args->npop*sizeof(*args->pop)); memset(args->pop+args->npop-1,0,sizeof(*args->pop)); args->pop[args->npop-1].name = pop_name; args->pop[args->npop-1].suffix = (char*)malloc(strlen(pop_name)+2); memcpy(args->pop[args->npop-1].suffix+1,pop_name,strlen(pop_name)+1); args->pop[args->npop-1].suffix[0] = '_'; } int ipop = 0; khash_str2int_get(pop2i,pop_name,&ipop); pop_t *pop = &args->pop[ipop]; pop->nsmpl++; pop->smpl = (int*) realloc(pop->smpl,pop->nsmpl*sizeof(*pop->smpl)); pop->smpl[pop->nsmpl-1] = ismpl; } nsmpl++; } if ( nsmpl != bcf_hdr_nsamples(args->in_hdr) ) fprintf(stderr,"Warning: %d samples in the list, %d samples in the VCF.\n", nsmpl,bcf_hdr_nsamples(args->in_hdr)); if ( !args->npop ) error("No populations given?\n"); khash_str2int_destroy(pop2i); khash_str2int_destroy_free(smpli); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } void init_pops(args_t *args) { int i,j, nsmpl; // add the population "ALL", which is a summary population for all samples args->npop++; args->pop = (pop_t*) realloc(args->pop,args->npop*sizeof(*args->pop)); memset(args->pop+args->npop-1,0,sizeof(*args->pop)); args->pop[args->npop-1].name = strdup(""); args->pop[args->npop-1].suffix = strdup(""); nsmpl = bcf_hdr_nsamples(args->in_hdr); args->smpl2pop = (pop_t**) calloc(nsmpl*(args->npop+1),sizeof(pop_t*)); for (i=0; ismpl2pop[i*(args->npop+1)] = &args->pop[args->npop-1]; for (i=0; inpop; i++) { for (j=0; jpop[i].nsmpl; j++) { int ismpl = args->pop[i].smpl[j]; pop_t **smpl2pop = &args->smpl2pop[ismpl*(args->npop+1)]; while (*smpl2pop) smpl2pop++; *smpl2pop = &args->pop[i]; } } } void ftf_destroy(pop_t *pop) { int i; for (i=0; inftf; i++) { ftf_t *ftf = &pop->ftf[i]; free(ftf->src_tag); free(ftf->dst_tag); free(ftf->fval); free(ftf->ival); if ( ftf->filter ) filter_destroy(ftf->filter); } free(pop->ftf); } #define float_set_from_double(dst, src) \ if (bcf_double_is_missing_or_vector_end(src)) bcf_float_set_missing(dst); else (dst) = (src) static inline int32_t int32_from_double(double src) { if (bcf_double_is_missing_or_vector_end(src)) return bcf_int32_missing; else return (int)src; } int ftf_filter_expr(args_t *args, bcf1_t *rec, pop_t *pop, ftf_t *ftf) { int j,k, nval, nval1; args->str.l = 0; ksprintf(&args->str, "%s%s", ftf->dst_tag,pop->suffix); filter_test(ftf->filter, rec, NULL); const double *val = filter_get_doubles(ftf->filter,&nval,&nval1); int ret; if ( ftf->info ) { int nfill = ftf->len==BCF_VL_FIXED ? ftf->cnt : nval; int ncopy = nval < nfill ? nval : nfill; // number of values available, the rest is filled with missing values if ( ftf->type==BCF_HT_REAL ) { hts_expand(float,nfill,ftf->nfval,ftf->fval); for (j=0; jfval[j], val[j]); for (; jfval[j]); ret = bcf_update_info_float(args->out_hdr,rec,args->str.s,ftf->fval,nfill); } else { hts_expand(int32_t,nfill,ftf->nival,ftf->ival); for (j=0; jival[j] = int32_from_double(val[j]); for (; jival[j] = bcf_int32_missing; ret = bcf_update_info_int32(args->out_hdr,rec,args->str.s,ftf->ival,nfill); } } else { int nfill = ftf->len==BCF_VL_FIXED ? ftf->cnt : nval1; int ncopy = nval1 < nfill ? nval1 : nfill; if ( ftf->type==BCF_HT_REAL ) { hts_expand(float,nfill*rec->n_sample,ftf->nfval,ftf->fval); for (k=0; kn_sample; k++) { float *dst = ftf->fval + k*nfill; const double *src = val + k*nval1; for (j=0; jout_hdr,rec,args->str.s,ftf->fval,nfill*rec->n_sample); } else { hts_expand(int32_t,nfill*rec->n_sample,ftf->nival,ftf->ival); for (k=0; kn_sample; k++) { int32_t *dst = ftf->ival + k*nfill; const double *src = val + k*nval1; for (j=0; jout_hdr,rec,args->str.s,ftf->ival,nfill*rec->n_sample); } } if ( ret ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); return 0; } // This is implemented as a macro so the compiler can properly validate the // printf format string. #define hdr_append(args, fmt) \ do { \ int i; \ for (i=0; inpop; i++) \ bcf_hdr_printf(args->out_hdr, fmt, args->pop[i].suffix,*args->pop[i].name ? " in " : "",args->pop[i].name); \ } while (0) int parse_func_pop(args_t *args, pop_t *pop, char *tag_expr, char *expr) { pop->nftf++; pop->ftf = (ftf_t *)realloc(pop->ftf,sizeof(*pop->ftf)*pop->nftf); ftf_t *ftf = &pop->ftf[ pop->nftf - 1 ]; memset(ftf,0,sizeof(ftf_t)); ftf->type = BCF_HT_REAL; ftf->len = BCF_VL_VAR; ftf->cnt = 0; ftf->info = 1; char *end = strchr(tag_expr,'='); char *beg = tag_expr; if ( !strncasecmp("info/",tag_expr,5) ) beg += 5; else if ( !strncasecmp("format/",tag_expr,7) ) { beg += 7; ftf->info = 0; } else if ( !strncasecmp("fmt/",tag_expr,4) ) { beg += 4; ftf->info = 0; } ftf->dst_tag = (char*)calloc(end-beg+1,1); memcpy(ftf->dst_tag, beg, end-beg); char *tmp, *cnt = strchr(ftf->dst_tag,':'); if ( cnt ) { *cnt = 0; ftf->cnt = strtol(cnt+1, &tmp, 10); if ( *tmp ) error("Could not parse the expression: %s\n",tag_expr); ftf->len = BCF_VL_FIXED; } char *filter = NULL; if ( expr[strlen(expr)-1]==')' ) { if ( !strncasecmp(expr,"int(",4) ) { filter = strdup(expr+4); ftf->type = BCF_HT_INT; } else if ( !strncasecmp(expr,"integer(",8) ) { filter = strdup(expr+8); ftf->type = BCF_HT_INT; } else if ( !strncasecmp(expr,"float(",6) ) { filter = strdup(expr+6); ftf->type = BCF_HT_REAL; } } if ( filter ) filter[strlen(filter)-1] = 0; else filter = strdup(expr); ftf->func = ftf_filter_expr; uint8_t *samples = (uint8_t*)calloc(bcf_hdr_nsamples(args->in_hdr),1); args->str.l = 0; ksprintf(&args->str, "%s%s", ftf->dst_tag,pop->suffix); int id = bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,args->str.s); int update_hdr = 1; if ( ftf->info && bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_INFO,id) ) { if ( bcf_hdr_id2length(args->in_hdr,BCF_HL_INFO,id)!=ftf->len ) error("Error: the field INFO/%s already exists and its Number definition is different\n",args->str.s); if ( ftf->len==BCF_VL_FIXED && bcf_hdr_id2number(args->in_hdr,BCF_HL_INFO,id)!=ftf->cnt ) error("Error: the field INFO/%s already exists and its Number definition is different from %d\n",args->str.s,ftf->cnt); if ( bcf_hdr_id2type(args->in_hdr,BCF_HT_INT,id)!=ftf->type ) error("Error: the field INFO/%s already exists and its Type definition is different\n",args->str.s); update_hdr = 0; } else if ( !ftf->info && bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,id) ) { if ( bcf_hdr_id2length(args->in_hdr,BCF_HL_FMT,id)!=ftf->len ) error("Error: the field FORMAT/%s already exists and its Number definition is different\n",args->str.s); if ( ftf->len==BCF_VL_FIXED && bcf_hdr_id2number(args->in_hdr,BCF_HL_FMT,id)!=ftf->cnt ) error("Error: the field FORMAT/%s already exists and its Number definition is different from %d\n",args->str.s,ftf->cnt); if ( bcf_hdr_id2type(args->in_hdr,BCF_HT_INT,id)!=ftf->type ) error("Error: the field FORMAT/%s already exists and its Type definition is different\n",args->str.s); update_hdr = 0; } if ( update_hdr ) { args->str.l = 0; ksprintf(&args->str, "##%s=info?"INFO":"FORMAT",ftf->dst_tag,pop->suffix); if ( ftf->len==BCF_VL_FIXED ) kputw(ftf->cnt, &args->str); else kputc('.', &args->str); kputs(",Type=", &args->str); if ( ftf->type==BCF_HT_INT ) kputs("Integer", &args->str); else kputs("Float", &args->str); kputs(",Description=\"Added by +fill-tags expression ", &args->str); // escape quotes char *tmp = tag_expr; while ( *tmp ) { if ( *tmp=='"' ) kputc('\\', &args->str); kputc(*tmp, &args->str); tmp++; } if ( *pop->name ) { kputs(" in ", &args->str); kputs(pop->name, &args->str); } kputs("\">", &args->str); bcf_hdr_append(args->out_hdr, args->str.s); } ftf->filter = filter_init(args->in_hdr, filter); args->unpack |= filter_max_unpack(ftf->filter); memset(samples,0,sizeof(*samples)*bcf_hdr_nsamples(args->in_hdr)); if ( *pop->name ) { int j; for (j=0; jnsmpl; j++) samples[ pop->smpl[j] ] = 1; filter_set_samples(ftf->filter, samples); } free(samples); free(filter); return SET_FUNC; } int parse_func(args_t *args, char *tag_expr, char *expr) { int i, ret = 0; for (i=0; inpop; i++) ret |= parse_func_pop(args,&args->pop[i],tag_expr,expr); return ret; } uint32_t parse_tags(args_t *args, const char *str) { if ( !args->in_hdr ) error("%s", usage()); args->warned = 0; uint32_t flag = 0; int i, n_tags; char **tags = hts_readlist(str, 0, &n_tags), *ptr; for(i=0; iwarned = ~(SET_END|SET_TYPE); args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"AN") || !strcasecmp(tags[i],"INFO/AN") ) { flag |= SET_AN; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"AC") || !strcasecmp(tags[i],"INFO/AC") ) { flag |= SET_AC; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"NS") || !strcasecmp(tags[i],"INFO/NS") ) { flag |= SET_NS; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"AC_Hom") || !strcasecmp(tags[i],"INFO/AC_Hom") ) { flag |= SET_AC_Hom; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"AC_Het") || !strcasecmp(tags[i],"INFO/AC_Het") ) { flag |= SET_AC_Het; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"AC_Hemi") || !strcasecmp(tags[i],"INFO_Hemi") ) { flag |= SET_AC_Hemi; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"AF") || !strcasecmp(tags[i],"INFO/AF") ) { flag |= SET_AF; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"MAF") || !strcasecmp(tags[i],"INFO/MAF") ) { flag |= SET_MAF; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"HWE") || !strcasecmp(tags[i],"INFO/HWE") ) { flag |= SET_HWE; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"ExcHet") || !strcasecmp(tags[i],"INFO/ExcHet") ) { flag |= SET_ExcHet; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"VAF") || !strcasecmp(tags[i],"FORMAT/VAF") ) { flag |= SET_VAF; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"VAF1") || !strcasecmp(tags[i],"FORMAT/VAF1") ) { flag |= SET_VAF1; args->unpack |= BCF_UN_FMT; } else if ( !strcasecmp(tags[i],"END") || !strcasecmp(tags[i],"INFO/END") ) flag |= SET_END; else if ( !strcasecmp(tags[i],"TYPE") || !strcasecmp(tags[i],"INFO/TYPE") ) flag |= SET_TYPE; else if ( !strcasecmp(tags[i],"F_MISSING") || !strcasecmp(tags[i],"INFO/F_MISSING") ) { flag |= parse_func(args,"F_MISSING=F_MISSING","F_MISSING"); args->unpack |= BCF_UN_FMT; } else if ( (ptr=strchr(tags[i],'=')) ) { flag |= parse_func(args,tags[i],ptr+1); args->unpack |= BCF_UN_FMT; } else { fprintf(stderr,"Error parsing \"--tags %s\": the tag \"%s\" is not supported\n", str,tags[i]); exit(1); } free(tags[i]); } if (n_tags) free(tags); return flag; } void list_tags(void) { error( "INFO/AC Number:A Type:Integer .. Allele count in genotypes\n" "INFO/AC_Hom Number:A Type:Integer .. Allele counts in homozygous genotypes\n" "INFO/AC_Het Number:A Type:Integer .. Allele counts in heterozygous genotypes\n" "INFO/AC_Hemi Number:A Type:Integer .. Allele counts in hemizygous genotypes\n" "INFO/AF Number:A Type:Float .. Allele frequency from FMT/GT or AC,AN if FMT/GT is not present\n" "INFO/AN Number:1 Type:Integer .. Total number of alleles in called genotypes\n" "INFO/ExcHet Number:A Type:Float .. Test excess heterozygosity; 1=good, 0=bad\n" "INFO/END Number:1 Type:Integer .. End position of the variant\n" "INFO/F_MISSING Number:1 Type:Float .. Fraction of missing genotypes (all samples, experimental)\n" "INFO/HWE Number:A Type:Float .. HWE test (PMID:15789306); 1=good, 0=bad\n" "INFO/MAF Number:1 Type:Float .. Frequency of the second most common allele\n" "INFO/NS Number:1 Type:Integer .. Number of samples with data\n" "INFO/TYPE Number:. Type:String .. The record type (REF,SNP,MNP,INDEL,etc)\n" "FORMAT/VAF Number:A Type:Float .. The fraction of reads with the alternate allele, requires FORMAT/AD or ADF+ADR\n" "FORMAT/VAF1 Number:1 Type:Float .. The same as FORMAT/VAF but for all alternate alleles cumulatively\n" "TAG:Number=Type(EXPR) .. Experimental support for user expressions such as DP:1=int(sum(DP))\n" " If Number and Type are not given (e.g. DP=sum(DP)), variable number (Number=.) of floating point\n" " values (Type=Float) will be used.\n" ); } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { args = (args_t*) calloc(1,sizeof(args_t)); args->in_hdr = in; args->out_hdr = out; char *samples_fname = NULL, *tags_str = "all"; static struct option loptions[] = { {"list-tags",0,0,'l'}, {"drop-missing",0,0,'d'}, {"tags",1,0,'t'}, {"samples-file",1,0,'S'}, {0,0,0,0} }; int c; while ((c = getopt_long(argc, argv, "?ht:dS:l",loptions,NULL)) >= 0) { switch (c) { case 'l': list_tags(); break; case 'd': args->drop_missing = 1; break; case 't': tags_str = optarg; break; case 'S': samples_fname = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } if ( optind != argc ) error("%s",usage()); if ( !in || !out ) error("%s",usage()); args->gt_id = bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,"GT"); if ( args->unpack&BCF_UN_FMT && args->gt_id<0 ) error("Error: GT field is not present\n"); if ( samples_fname ) parse_samples(args, samples_fname); init_pops(args); args->tags |= parse_tags(args,tags_str); if ( args->tags & SET_AN ) hdr_append(args, "##INFO="); if ( args->tags & SET_AC ) hdr_append(args, "##INFO="); if ( args->tags & SET_NS ) hdr_append(args, "##INFO="); if ( args->tags & SET_AC_Hom ) hdr_append(args, "##INFO="); if ( args->tags & SET_AC_Het ) hdr_append(args, "##INFO="); if ( args->tags & SET_AC_Hemi ) hdr_append(args, "##INFO="); if ( args->tags & SET_AF ) hdr_append(args, "##INFO="); if ( args->tags & SET_MAF ) hdr_append(args, "##INFO="); if ( args->tags & SET_HWE ) hdr_append(args, "##INFO="); if ( args->tags & SET_END ) bcf_hdr_printf(args->out_hdr, "##INFO="); if ( args->tags & SET_TYPE ) bcf_hdr_printf(args->out_hdr, "##INFO="); if ( args->tags & SET_ExcHet ) hdr_append(args, "##INFO="); if ( args->tags & SET_VAF ) bcf_hdr_append(args->out_hdr, "##FORMAT="); if ( args->tags & SET_VAF1 ) bcf_hdr_append(args->out_hdr, "##FORMAT="); int i, max_unpack_bit = 0; for (i=0; i<=3; i++) if ( args->unpack & (1<unpack |= 1<mhwe_probs,args->hwe_probs); memset(args->hwe_probs, 0, sizeof(*args->hwe_probs)*(nrare+1)); double *probs = args->hwe_probs; // start at midpoint int mid = (double)nrare * (nref + nalt - nrare) / (nref + nalt); // check to ensure that midpoint and rare alleles have same parity if ( (nrare & 1) ^ (mid & 1) ) mid++; int het = mid; int hom_r = (nrare - mid) / 2; int hom_c = ngt - het - hom_r; double sum = probs[mid] = 1.0; for (het = mid; het > 1; het -= 2) { probs[het - 2] = probs[het] * het * (het - 1.0) / (4.0 * (hom_r + 1.0) * (hom_c + 1.0)); sum += probs[het - 2]; // 2 fewer heterozygotes for next iteration -> add one rare, one common homozygote hom_r++; hom_c++; } het = mid; hom_r = (nrare - mid) / 2; hom_c = ngt - het - hom_r; for (het = mid; het <= nrare - 2; het += 2) { probs[het + 2] = probs[het] * 4.0 * hom_r * hom_c / ((het + 2.0) * (het + 1.0)); sum += probs[het + 2]; // add 2 heterozygotes for next iteration -> subtract one rare, one common homozygote hom_r--; hom_c--; } for (het=0; het probs[nhet]) continue; prob += probs[het]; } if ( prob > 1 ) prob = 1; *p_hwe = prob; } static inline void set_counts(pop_t *pop, int is_half, int is_hom, int is_hemi, kbitset_t *bset) { kbitset_iter_t itr; int i; kbs_start(&itr); while ((i = kbs_next(bset, &itr)) >= 0) { if ( is_half ) pop->counts[i].nac++; else if ( !is_hom ) pop->counts[i].nhet++; else if ( !is_hemi ) pop->counts[i].nhom += 2; else pop->counts[i].nhemi++; } pop->ns++; } static void clean_counts(pop_t *pop, int nals) { pop->ns = 0; memset(pop->counts,0,sizeof(counts_t)*nals); } static int cmpfloat_desc(const void *a, const void *b) { float fa = *((float*)a); float fb = *((float*)b); if ( fafb ) return -1; return 0; } static void process_fmt(bcf1_t *rec) { int i,j, nsmpl = bcf_hdr_nsamples(args->in_hdr);; bcf_fmt_t *fmt_gt = NULL; for (i=0; in_fmt; i++) if ( rec->d.fmt[i].id==args->gt_id ) { fmt_gt = &rec->d.fmt[i]; break; } if ( !fmt_gt ) return; // no GT tag hts_expand(int32_t,rec->n_allele, args->miarr, args->iarr); hts_expand(float,rec->n_allele*2, args->mfarr, args->farr); for (i=0; inpop; i++) hts_expand(counts_t,rec->n_allele,args->pop[i].mcounts, args->pop[i].counts); for (i=0; inpop; i++) clean_counts(&args->pop[i], rec->n_allele); if ( kbs_resize(&args->bset, rec->n_allele) < 0 ) error("kbs_resize: failed to store %d bits\n", rec->n_allele); #define BRANCH_INT(type_t,vector_end) \ { \ for (i=0; ip + i*fmt_gt->size); \ int ial, nbits = 0, nals = 0, is_half, is_hom, is_hemi; \ kbs_clear(args->bset); \ for (ial=0; ialn; ial++) \ { \ if ( p[ial]==vector_end ) break; /* smaller ploidy */ \ if ( bcf_gt_is_missing(p[ial]) ) continue; /* missing allele */ \ int idx = bcf_gt_allele(p[ial]); \ nals++; \ \ if ( idx >= rec->n_allele ) \ error("Incorrect allele (\"%d\") in %s at %s:%"PRId64"\n",idx,args->in_hdr->samples[i],bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); \ if ( !kbs_exists(args->bset, idx) ) nbits++; \ kbs_insert(args->bset, idx); \ } \ if ( nals==0 ) continue; /* missing genotype */ \ is_hom = nbits==1 ? 1 : 0; /* only one bit is set for homs */ \ if ( nals!=ial ) \ { \ if ( args->drop_missing ) is_hemi = 0, is_half = 1; \ else is_hemi = 1, is_half = 0; \ } \ else if ( nals==1 ) is_hemi = 1, is_half = 0; \ else is_hemi = 0, is_half = 0; \ pop_t **pop = &args->smpl2pop[i*(args->npop+1)]; \ while ( *pop ) { set_counts(*pop,is_half,is_hom,is_hemi,args->bset); pop++; } \ } \ } switch (fmt_gt->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break; default: error("The GT type is not recognised: %d at %s:%"PRId64"\n",fmt_gt->type, bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); break; } #undef BRANCH_INT if ( args->tags & SET_NS ) { for (i=0; inpop; i++) { args->str.l = 0; ksprintf(&args->str, "NS%s", args->pop[i].suffix); if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,&args->pop[i].ns,1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } if ( args->tags & SET_AN ) { for (i=0; inpop; i++) { pop_t *pop = &args->pop[i]; int32_t an = 0; for (j=0; jn_allele; j++) an += pop->counts[j].nhet + pop->counts[j].nhom + pop->counts[j].nhemi + pop->counts[j].nac; args->str.l = 0; ksprintf(&args->str, "AN%s", args->pop[i].suffix); if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,&an,1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } if ( args->tags & (SET_AF | SET_MAF) ) { for (i=0; inpop; i++) { int32_t an = 0; if ( rec->n_allele > 1 ) { pop_t *pop = &args->pop[i]; for (j=0; jn_allele; j++) { args->farr[j] = pop->counts[j].nhet + pop->counts[j].nhom + pop->counts[j].nhemi + pop->counts[j].nac; an += args->farr[j]; } if ( an ) for (j=0; jn_allele; j++) args->farr[j] /= an; else for (j=0; jn_allele; j++) bcf_float_set_missing(args->farr[j]); } if ( args->tags & SET_AF ) { args->str.l = 0; ksprintf(&args->str, "AF%s", args->pop[i].suffix); if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,args->farr+1,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } if ( rec->n_allele > 1 && args->tags & SET_MAF ) { if ( an ) qsort(args->farr,rec->n_allele,sizeof(float),cmpfloat_desc); args->str.l = 0; ksprintf(&args->str, "MAF%s", args->pop[i].suffix); if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,args->farr+1,1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } } if ( args->tags & SET_AC ) { for (i=0; inpop; i++) { if ( rec->n_allele > 1 ) { pop_t *pop = &args->pop[i]; for (j=0; jn_allele; j++) args->iarr[j] = pop->counts[j].nhet + pop->counts[j].nhom + pop->counts[j].nhemi + pop->counts[j].nac; } args->str.l = 0; ksprintf(&args->str, "AC%s", args->pop[i].suffix); if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr+1,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } if ( args->tags & SET_AC_Het ) { for (i=0; inpop; i++) { if ( rec->n_allele > 1 ) { pop_t *pop = &args->pop[i]; memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); for (j=1; jn_allele; j++) args->iarr[j-1] += pop->counts[j].nhet; } args->str.l = 0; ksprintf(&args->str, "AC_Het%s", args->pop[i].suffix); if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } if ( args->tags & SET_AC_Hom ) { for (i=0; inpop; i++) { if ( rec->n_allele > 1 ) { pop_t *pop = &args->pop[i]; memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); for (j=1; jn_allele; j++) args->iarr[j-1] += pop->counts[j].nhom; } args->str.l = 0; ksprintf(&args->str, "AC_Hom%s", args->pop[i].suffix); if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } if ( args->tags & SET_AC_Hemi && rec->n_allele > 1 ) { for (i=0; inpop; i++) { if ( rec->n_allele > 1 ) { pop_t *pop = &args->pop[i]; memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); for (j=1; jn_allele; j++) args->iarr[j-1] += pop->counts[j].nhemi; } args->str.l = 0; ksprintf(&args->str, "AC_Hemi%s", args->pop[i].suffix); if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } if ( args->tags & (SET_HWE|SET_ExcHet) ) { for (i=0; inpop; i++) { float *fhwe = args->farr; float *fexc_het = args->farr + rec->n_allele; if ( rec->n_allele > 1 ) { pop_t *pop = &args->pop[i]; memset(args->farr, 0, sizeof(*args->farr)*(2*rec->n_allele)); int nref_tot = pop->counts[0].nhom; for (j=0; jn_allele; j++) nref_tot += pop->counts[j].nhet; // NB this neglects multiallelic genotypes for (j=1; jn_allele; j++) { int nref = nref_tot - pop->counts[j].nhet; int nalt = pop->counts[j].nhet + pop->counts[j].nhom; int nhet = pop->counts[j].nhet; if ( nref>0 && nalt>0 ) calc_hwe(args, nref, nalt, nhet, &fhwe[j-1], &fexc_het[j-1]); else fhwe[j-1] = fexc_het[j-1] = 1; } } if ( args->tags & SET_HWE ) { args->str.l = 0; ksprintf(&args->str, "HWE%s", args->pop[i].suffix); if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,fhwe,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } if ( args->tags & SET_ExcHet ) { args->str.l = 0; ksprintf(&args->str, "ExcHet%s", args->pop[i].suffix); if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,fexc_het,rec->n_allele-1)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } } } static void process_info_af(bcf1_t *rec) { if ( !(args->tags & SET_AF) ) return; if ( bcf_hdr_nsamples(args->in_hdr) ) return; int n = bcf_get_info_int32(args->in_hdr,rec,"AN",&args->iarr,&args->miarr); if ( n!=1 ) return; int an = args->iarr[0]; if ( !an ) return; n = bcf_get_info_int32(args->in_hdr,rec,"AC",&args->iarr,&args->miarr); if ( n!=rec->n_allele-1 ) return; hts_expand(float,n,args->mfarr,args->farr); int i; for (i=0; ifarr[i] = (double)args->iarr[i]/an; if ( bcf_update_info_float(args->out_hdr,rec,"AF", args->farr, n)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } static void process_vaf(bcf1_t *rec, int mode) { int nsmpl = bcf_hdr_nsamples(args->in_hdr); int nval = args->niarr / nsmpl; int nval1 = (mode & SET_VAF) ? rec->n_allele - 1 : 1; int nfarr = nval1 * nsmpl; hts_expand(float,nfarr,args->mfarr,args->farr); int i,j; for (i=0; iiarr + i*nval; float *dst = args->farr + i*nval1; float sum = 0; for (j=0; jout_hdr,rec,(mode & SET_VAF) ? "VAF" : "VAF1", args->farr, nfarr)!=0 ) error("Error occurred while updating %s at %s:%"PRId64"\n", args->str.s,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } static void process_vaf_vaf1(bcf1_t *rec) { if ( !(args->tags & (SET_VAF|SET_VAF1)) ) return; if ( rec->n_allele <= 1 ) return; args->niarr = bcf_get_format_int32(args->in_hdr, rec, "AD", &args->iarr, &args->miarr); if ( args->niarr <= 0 ) { if ( !(args->warned&(SET_VAF|SET_VAF1)) ) fprintf(stderr,"Warning: cannot add the VAF/VAF1 annotations, the required FORMAT/AD tag is missing at %s:%"PRIhts_pos".\n" " (This warning is printed only once.)\n",bcf_seqname(args->in_hdr,rec),rec->pos+1); args->warned |= SET_VAF|SET_VAF1; return; } int nsmpl = bcf_hdr_nsamples(args->in_hdr); if ( args->niarr != nsmpl*rec->n_allele ) return; // incorrect number of values (possibly all missing) if ( args->tags & SET_VAF ) process_vaf(rec, SET_VAF); if ( args->tags & SET_VAF1 ) process_vaf(rec, SET_VAF1); } bcf1_t *process(bcf1_t *rec) { int i,j; bcf_unpack(rec, args->unpack); for (i=0; inpop; i++) for (j=0; jpop[i].nftf; j++) args->pop[i].ftf[j].func(args, rec, &args->pop[i], &args->pop[i].ftf[j]); if ( args->unpack & BCF_UN_FMT ) { process_fmt(rec); process_info_af(rec); process_vaf_vaf1(rec); } if ( args->tags & SET_END ) { int32_t end = rec->pos + rec->rlen; if ( bcf_update_info_int32(args->out_hdr,rec,"END",&end,1)!=0 ) error("Error occurred while updating INFO/END at %s:%"PRId64"\n", bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } if ( args->tags & SET_TYPE ) { int type = bcf_get_variant_types(rec); args->str.l = 0; if ( type == VCF_REF ) kputs("REF,", &args->str); if ( type & VCF_SNP ) kputs("SNP,", &args->str); if ( type & VCF_MNP ) kputs("MNP,", &args->str); if ( type & VCF_INDEL ) kputs("INDEL,", &args->str); if ( type & VCF_OTHER ) kputs("OTHER,", &args->str); if ( type & VCF_BND ) kputs("BND,", &args->str); if ( type & VCF_OVERLAP ) kputs("OVERLAP,", &args->str); if ( args->str.l ) { args->str.s[args->str.l-1] = 0; if ( bcf_update_info_string(args->out_hdr,rec,"TYPE",args->str.s)!=0 ) error("Error occurred while updating INFO/TYPE at %s:%"PRId64"\n", bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); } } return rec; } void destroy(void) { int i; for (i=0; inpop; i++) { free(args->pop[i].name); free(args->pop[i].suffix); free(args->pop[i].smpl); free(args->pop[i].counts); ftf_destroy(&args->pop[i]); } kbs_destroy(args->bset); free(args->str.s); free(args->pop); free(args->smpl2pop); free(args->iarr); free(args->farr); free(args->hwe_probs); free(args); } bcftools-1.21/plugins/fixploidy.c000066400000000000000000000207661467060157400171310ustar00rootroot00000000000000/* Copyright (C) 2014, 2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "ploidy.h" static bcf_hdr_t *in_hdr = NULL, *out_hdr = NULL; static int *sample2sex = NULL; static int n_sample = 0, nsex = 0, *sex2ploidy = NULL; static int32_t ngt_arr = 0, *gt_arr = NULL, *gt_arr2 = NULL, ngt_arr2 = 0; static ploidy_t *ploidy = NULL; static int force_ploidy = -1; const char *about(void) { return "Fix ploidy.\n"; } const char *usage(void) { return "\n" "About: Fix ploidy\n" "Usage: bcftools +fixploidy [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -d, --default-ploidy default ploidy for regions unlisted in -p [2]\n" " -f, --force-ploidy ignore -p, set the same ploidy for all genotypes\n" " -p, --ploidy space/tab-delimited list of CHROM,FROM,TO,SEX,PLOIDY\n" " -s, --sex list of samples, \"NAME SEX\"\n" " -t, --tags VCF tags to fix [GT]\n" "\n" "Example:\n" " # Default ploidy, if -p not given. Unlisted regions have ploidy 2\n" " X 1 60000 M 1\n" " X 2699521 154931043 M 1\n" " Y 1 59373566 M 1\n" " Y 1 59373566 F 0\n" " MT 1 16569 M 1\n" " MT 1 16569 F 1\n" " \n" " # Example of -s file, sex of unlisted samples is \"F\"\n" " sampleName1 M\n" " \n" " bcftools +fixploidy in.vcf -- -s samples.txt\n" "\n"; } void set_samples(char *fname, bcf_hdr_t *hdr, ploidy_t *ploidy, int *sample2sex) { kstring_t tmp = {0,0,0}; htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); while ( hts_getline(fp, KS_SEP_LINE, &tmp) > 0 ) { char *ss = tmp.s; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) error("Could not parse: %s\n", tmp.s); if ( *ss=='#' ) continue; char *se = ss; while ( *se && !isspace(*se) ) se++; char x = *se; *se = 0; int ismpl = bcf_hdr_id2int(hdr, BCF_DT_SAMPLE, ss); if ( ismpl < 0 ) { fprintf(stderr,"Warning: No such sample in the VCF: %s\n",ss); continue; } *se = x; ss = se+1; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) error("Could not parse: %s\n", tmp.s); se = ss; while ( *se && !isspace(*se) ) se++; if ( se==ss ) error("Could not parse: %s\n", tmp.s); sample2sex[ismpl] = ploidy_add_sex(ploidy, ss); } if ( hts_close(fp) ) error("Close failed: %s\n", fname); free(tmp.s); } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { int c, default_ploidy = 2; char *tags_str = "GT"; char *ploidy_fname = NULL, *sex_fname = NULL; static struct option loptions[] = { {"default-ploidy",1,0,'d'}, {"force-ploidy",1,0,'f'}, {"ploidy",1,0,'p'}, {"sex",1,0,'s'}, {"tags",1,0,'t'}, {0,0,0,0} }; char *tmp; while ((c = getopt_long(argc, argv, "?ht:s:p:d:f:",loptions,NULL)) >= 0) { switch (c) { case 'd': default_ploidy = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -d %s\n", optarg); break; case 'f': force_ploidy = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -f %s\n", optarg); break; case 'p': ploidy_fname = optarg; break; case 's': sex_fname = optarg; break; case 't': tags_str = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } if ( strcasecmp("GT",tags_str) ) error("Only -t GT is currently supported, sorry\n"); n_sample = bcf_hdr_nsamples(in); sample2sex = (int*) calloc(n_sample,sizeof(int)); in_hdr = in; out_hdr = out; if ( ploidy_fname ) ploidy = ploidy_init(ploidy_fname, default_ploidy); else if ( force_ploidy==-1 ) { ploidy = ploidy_init_string( "X 1 60000 M 1\n" "X 2699521 154931043 M 1\n" "Y 1 59373566 M 1\n" "Y 1 59373566 F 0\n" "MT 1 16569 M 1\n" "MT 1 16569 F 1\n", 2); } if ( force_ploidy==-1 ) { if ( !ploidy ) return -1; // add default sex in case it was not included int i, dflt_sex_id = ploidy_add_sex(ploidy, "F"); for (i=0; ipos+1); if ( force_ploidy==-1 ) ploidy_query(ploidy, (char*)bcf_seqname(in_hdr,rec), rec->pos, sex2ploidy,NULL,&max_ploidy); else max_ploidy = force_ploidy; ngts /= n_sample; if ( ngts < max_ploidy ) { hts_expand(int32_t,max_ploidy*n_sample,ngt_arr2,gt_arr2); for (i=0; ipos+1); } else if ( ngts!=1 || max_ploidy!=1 ) { for (i=0; ipos+1); } return rec; } void destroy(void) { free(gt_arr); free(gt_arr2); free(sample2sex); free(sex2ploidy); if ( ploidy ) ploidy_destroy(ploidy); } bcftools-1.21/plugins/fixploidy.mk000066400000000000000000000003541467060157400173050ustar00rootroot00000000000000plugins/fixploidy.so: plugins/fixploidy.c version.h version.c regidx.h regidx.c ploidy.h ploidy.c $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ ploidy.c regidx.c version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/fixref.c000066400000000000000000000566631467060157400164120ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Illumina TOP/BOT strand convention causes a lot of pain. This tool attempts to determine the strand convention and convert it to the forward reference strand. On TOP strand, we can encounter unambiguous SNPs: A/G A/C ambiguous (context-dependent) SNPs: C/G A/T On BOT strand: unambiguous SNPs: T/G T/C ambiguous (context-dependent) SNPs: T/A G/C For unambiguous pairs (A/C, A/G, T/C, T/G), the knowledge of reference base at the SNP position is enough to determine the strand: TOP REF -> ALLELES TOP_ON_STRAND ------------------------------------------- A/C A or C A/C 1 " T or G T/G -1 A/G A or G A/G 1 " T or C T/C -1 For ambiguous pairs (A/T, C/G), a sequence walking must be performed (simultaneously upstream and downstream) until the first unambiguous pair is encountered. The 5' base determines the strand: TOP 5'REF_BASE -> ALLELES TOP_ON_STRAND ------------------------------------------------ A/T A or T A/T 1 " C or G T/A -1 C/G A or T C/G 1 " C or G G/C -1 */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #define MODE_STATS 1 #define MODE_TOP2FWD 2 #define MODE_FLIP2FWD 3 #define MODE_USE_ID 4 #define MODE_REF_ALT 5 #define MODE_FLIP_ALL 6 #define MODE_SWAP_REF_ALT 7 #define FIX_ERR (1<<0) #define FIX_SKIP (1<<1) #define FIX_NONE (1<<2) #define FIX_FLIP (1<<3) #define FIX_SWAP (1<<4) #define FIX_GT (1<<5) const char *info_annots[] = {"err","skip","none","flip","swap","GT"}; typedef struct { uint32_t pos; uint8_t ref; } marker_t; KHASH_MAP_INIT_STR(i2m, marker_t) typedef khash_t(i2m) i2m_t; typedef struct { char *dbsnp_fname; int mode, discard; bcf_hdr_t *hdr_in, *hdr_out; faidx_t *fai; int rid, skip_rid; i2m_t *i2m; int32_t *gts, ngts, pos; uint32_t nsite,nok,nflip,nunresolved,nswap,nflip_swap,nonSNP,nonACGT,nonbiallelic,nerr; uint32_t count[4][4], npos_err, unsorted; uint32_t dirty; kstring_t str; char *info_tag; } args_t; args_t args; const char *about(void) { return "Fix reference strand orientation, e.g. from Illumina/TOP to fwd.\n"; } const char *usage(void) { return "\n" "About: This tool helps to determine and fix strand orientation.\n" " Currently the following modes are recognised:\n" " flip .. swap or flip REF/ALT columns and GTs for non-ambiguous SNPs and ignore the rest\n" " flip-all .. swap or flip REF/ALT columns and GTs for all SNPs, including ambiguous (A/T, C/G) sites\n" " id .. swap or flip REF/ALT columns and GTs using the ID column to determine the REF allele\n" " ref-alt .. swap or flip REF/ALT columns to match the reference, do not modify the genotypes\n" " stats .. collect and print stats\n" " swap .. swap REF/ALT columns to match the reference, do not modify the genotypes\n" " top .. convert from Illumina TOP strand to fwd\n" " Each record is annotated with the INFO/FIXREF tag which records what change was made:\n" " err .. the alleles are invalid and could not be repaired\n" " skip .. the record was not considered at all (e.g. multiallelic or indel)\n" " none .. the alleles were valid and no change was required\n" " flip .. the REF and ALT alleles were flipped (e.g. A,C -> T,G)\n" " swap .. the REF and ALT columns were swapped (e.g. A,C -> C,A)\n" " GT .. FORMAT/GT was modified to reflect REF,ALT swap (e.g. 1/1 -> 0/0)\n" "\n" " WARNING: Do not use the program blindly, make an effort to\n" " understand what strand convention your data uses! Make sure\n" " the reason for mismatching REF alleles is not a different\n" " reference build!!\n" "\n" " Please check this page before messing up your VCF even more\n" " http://samtools.github.io/bcftools/howtos/plugin.fixref.html\n" "\n" "Usage: bcftools +fixref [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -d, --discard Discard sites which could not be resolved\n" " -f, --fasta-ref FILE.fa Reference sequence\n" " -i, --use-id FILE.vcf Swap REF/ALT using the ID column to determine the REF allele, implies -m id.\n" " Download the dbSNP file from\n" " https://www.ncbi.nlm.nih.gov/variation/docs/human_variation_vcf\n" " -m, --mode STRING Collect statistics (\"stats\") or convert (see the list of modes above) [stats]\n" " -t, --tag-name STRING The name of the INFO annotation to record what change was made [FIXREF]\n" "\n" "Examples:\n" " # run stats\n" " bcftools +fixref file.bcf -- -f ref.fa\n" "\n" " # convert from TOP to fwd\n" " bcftools +fixref file.bcf -Ob -o out.bcf -- -f ref.fa -m top\n" "\n" " # match the REF/ALT alleles based on the ID column, discard unknown sites\n" " bcftools +fixref file.bcf -Ob -o out.bcf -- -d -f ref.fa -i All_20151104.vcf.gz\n" "\n" " # assuming the reference build is correct, just flip to fwd, discarding the rest\n" " bcftools +fixref file.bcf -Ob -o out.bcf -- -d -f ref.fa -m flip\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { memset(&args,0,sizeof(args_t)); args.skip_rid = -1; args.hdr_in = in; args.hdr_out = out; args.mode = MODE_STATS; args.info_tag = "FIXREF"; char *ref_fname = NULL; static struct option loptions[] = { {"mode",required_argument,NULL,'m'}, {"tag-name",required_argument,NULL,'t'}, {"discard",no_argument,NULL,'d'}, {"fasta-ref",required_argument,NULL,'f'}, {"use-id",required_argument,NULL,'i'}, {NULL,0,NULL,0} }; int c; while ((c = getopt_long(argc, argv, "?hf:m:di:t:",loptions,NULL)) >= 0) { switch (c) { case 'm': if ( !strcasecmp(optarg,"top") ) args.mode = MODE_TOP2FWD; else if ( !strcasecmp(optarg,"flip") ) args.mode = MODE_FLIP2FWD; else if ( !strcasecmp(optarg,"flip-all") ) args.mode = MODE_FLIP_ALL; else if ( !strcasecmp(optarg,"id") ) args.mode = MODE_USE_ID; else if ( !strcasecmp(optarg,"ref-alt") ) args.mode = MODE_REF_ALT; else if ( !strcasecmp(optarg,"swap") ) args.mode = MODE_SWAP_REF_ALT; else if ( !strcasecmp(optarg,"stats") ) args.mode = MODE_STATS; else error("The source strand convention not recognised: %s\n", optarg); break; case 'i': args.dbsnp_fname = optarg; args.mode = MODE_USE_ID; break; case 'd': args.discard = 1; break; case 'f': ref_fname = optarg; break; case 't': args.info_tag = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } if ( !ref_fname ) error("Expected the -f option\n"); args.fai = fai_load(ref_fname); if ( !args.fai ) error("Failed to load the fai index: %s\n", ref_fname); if ( bcf_hdr_printf(args.hdr_out,"##INFO=",args.info_tag) ) return -1; if ( args.mode==MODE_STATS ) return 1; return 0; } static bcf1_t *set_ref_alt(args_t *args, bcf1_t *rec, const char ref, const char alt, int swap_gt) { rec->d.allele[0][0] = ref; rec->d.allele[1][0] = alt; rec->d.shared_dirty |= BCF1_DIRTY_ALS; if ( !swap_gt ) return rec; // only fix the alleles, leaving GTs unchanged int ngts = bcf_get_genotypes(args->hdr_in, rec, &args->gts, &args->ngts); if ( ngts<=0 ) return rec; // no samples, no genotypes int i, j, nsmpl = bcf_hdr_nsamples(args->hdr_in); ngts /= nsmpl; for (i=0; igts + i*ngts; for (j=0; jhdr_out,rec,args->gts,args->ngts); return rec; } static inline int nt2int(char nt) { nt = toupper(nt); if ( nt=='A' ) return 0; if ( nt=='C' ) return 1; if ( nt=='G' ) return 2; if ( nt=='T' ) return 3; return -1; } #define int2nt(x) "ACGT"[x] #define revint(x) ("3210"[x]-'0') static int fetch_ref(args_t *args, bcf1_t *rec) { // Get the reference allele int len; char *ref = faidx_fetch_seq(args->fai, (char*)bcf_seqname(args->hdr_in,rec), rec->pos, rec->pos, &len); if ( !ref ) { if ( faidx_has_seq(args->fai, bcf_seqname(args->hdr_in,rec))==0 ) { fprintf(stderr,"Ignoring sequence \"%s\"\n", bcf_seqname(args->hdr_in,rec)); args->skip_rid = rec->rid; return -2; } error("faidx_fetch_seq failed at %s:%"PRId64"\n", bcf_seqname(args->hdr_in,rec),(int64_t) rec->pos+1); } int ir = nt2int(*ref); free(ref); return ir; } static void dbsnp_destroy(args_t *args) { if ( !args->i2m ) return; khint_t k; for (k = 0; k < kh_end(args->i2m); ++k) if (kh_exist(args->i2m, k)) free((char*)kh_key(args->i2m, k)); kh_destroy(i2m, args->i2m); } static void dbsnp_init(args_t *args, const char *chr) { dbsnp_destroy(args); args->i2m = kh_init(i2m); bcf_srs_t *sr = bcf_sr_init(); if ( bcf_sr_set_regions(sr, chr, 0) != 0 ) goto done; if ( !args->dbsnp_fname ) error("No ID file specified, use -i/--use-id\n"); if ( !bcf_sr_add_reader(sr,args->dbsnp_fname) ) error("Failed to open %s: %s\n", args->dbsnp_fname,bcf_sr_strerror(sr->errnum)); while ( bcf_sr_next_line(sr) ) { bcf1_t *rec = bcf_sr_get_line(sr, 0); if ( rec->d.allele[0][1]!=0 || rec->d.allele[1][1]!=0 ) continue; // skip non-snps int ref = nt2int(rec->d.allele[0][0]); if ( ref<0 ) continue; // non-[ACGT] base if ( !rec->d.id || (rec->d.id[0]=='.' && !rec->d.id[1]) ) continue; char *id = strdup(rec->d.id); int ret, k; k = kh_put(i2m, args->i2m, id, &ret); if ( ret<0 ) error("An error occurred while inserting the key \"%s\"\n", id); if ( ret==0 ) { free(id); continue; } // skip ambiguous id kh_val(args->i2m, k).pos = (uint32_t)rec->pos; kh_val(args->i2m, k).ref = ref; } done: bcf_sr_destroy(sr); } static bcf1_t *dbsnp_check(args_t *args, bcf1_t *rec, int ir, int ia, int ib) { int k, ref,pos; char *id = rec->d.id; if ( !id || (id[0]=='.' && !id[1]) ) goto no_info; k = kh_get(i2m, args->i2m, id); if ( k==kh_end(args->i2m) ) goto no_info; pos = (int)kh_val(args->i2m, k).pos; if ( pos != rec->pos ) { rec->pos = pos; ir = fetch_ref(args, rec); args->npos_err++; } ref = kh_val(args->i2m, k).ref; if ( ref!=ir ) error("Reference base mismatch at %s:%"PRId64" .. %c vs %c\n",bcf_seqname(args->hdr_in,rec),(int64_t) rec->pos+1,int2nt(ref),int2nt(ir)); if ( ia==ref ) { args->dirty = FIX_NONE; return rec; } if ( ib==ref ) { args->dirty = FIX_SWAP; args->nswap++; return set_ref_alt(args,rec,int2nt(ib),int2nt(ia),1); } no_info: args->nunresolved++; return args->discard ? NULL : rec; } static bcf1_t *process_record(bcf1_t *rec) { if ( rec->rid == args.skip_rid ) return NULL; bcf1_t *ret = args.mode==MODE_STATS ? NULL : rec; args.nsite++; args.dirty = FIX_SKIP; // Skip non-SNPs if ( bcf_get_variant_types(rec)!=VCF_SNP ) { args.nonSNP++; return args.discard ? NULL : ret; } // Get the reference allele int ir = fetch_ref(&args, rec); if ( ir==-2 ) return NULL; if ( ir==-1 ) { args.nonACGT++; return args.discard ? NULL : ret; // not A,C,G,T } if ( rec->n_allele!=2 ) { // not a biallelic site args.nonbiallelic++; return args.discard ? NULL : ret; } int ia = nt2int(rec->d.allele[0][0]); if ( ia<0 ) { // not A,C,G,T args.nonACGT++; return args.discard ? NULL : ret; } int ib = nt2int(rec->d.allele[1][0]); if ( ib<0 ) { // not A,C,G,T args.nonACGT++; return args.discard ? NULL : ret; } if ( ia==ib ) { // should not happen in well-formed VCF args.nonSNP++; return args.discard ? NULL : ret; } args.count[ia][ib]++; if ( ir==ia ) args.nok++; if ( args.mode==MODE_USE_ID ) { if ( !args.i2m || args.rid!=rec->rid ) { args.pos = 0; args.rid = rec->rid; dbsnp_init(&args,bcf_seqname(args.hdr_in,rec)); } ret = dbsnp_check(&args, rec, ir,ia,ib); if ( !args.unsorted && args.pos > rec->pos ) { fprintf(stderr, "Warning: corrected position(s) results in unsorted VCF, for example %s:%"PRId64" comes after %s:%d\n" " The command `bcftools sort` can be used to fix the order.\n", bcf_seqname(args.hdr_in,rec),(int64_t) rec->pos+1,bcf_seqname(args.hdr_in,rec),args.pos); args.unsorted = 1; } args.pos = rec->pos; return ret; } if ( args.mode==MODE_REF_ALT ) // only change the REF/ALT column, leave the genotypes as is { if ( ir==ia ) { args.dirty = FIX_NONE; return ret; } if ( ir==ib ) { args.dirty = FIX_SWAP; args.nswap++; return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),0); } if ( ir==revint(ia) ) { args.dirty = FIX_FLIP; args.nflip++; return set_ref_alt(&args,rec,int2nt(revint(ia)),int2nt(revint(ib)),0); } if ( ir==revint(ib) ) { args.dirty = FIX_FLIP|FIX_SWAP; args.nflip_swap++; return set_ref_alt(&args,rec,int2nt(revint(ib)),int2nt(revint(ia)),0); } args.dirty = FIX_ERR; args.nerr++; return ret; } if ( args.mode==MODE_SWAP_REF_ALT ) // only swap the REF/ALT column but never flip, leave the genotypes as is { if ( ir==ia ) { args.dirty = FIX_NONE; return ret; } if ( ir==ib ) { args.dirty = FIX_SWAP; args.nswap++; return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),0); } args.dirty = FIX_ERR; args.nerr++; return ret; } if ( args.mode==MODE_FLIP2FWD || args.mode==MODE_FLIP_ALL ) { int pair = 1 << ia | 1 << ib; if ( args.mode==MODE_FLIP2FWD && (pair==0x9 || pair==0x6) ) // skip ambiguous pairs: A/T or C/G { args.nunresolved++; return args.discard ? NULL : ret; } if ( ir==ia ) { args.dirty = FIX_NONE; return ret; } if ( ir==ib ) { args.dirty = FIX_SWAP|FIX_GT; args.nswap++; return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),1); } if ( ir==revint(ia) ) { args.dirty = FIX_FLIP; args.nflip++; return set_ref_alt(&args,rec,int2nt(revint(ia)),int2nt(revint(ib)),0); } if ( ir==revint(ib) ) { args.dirty = FIX_FLIP|FIX_SWAP|FIX_GT; args.nflip_swap++; return set_ref_alt(&args,rec,int2nt(revint(ib)),int2nt(revint(ia)),1); } args.dirty = FIX_ERR; args.nerr++; return ret; } if ( args.mode==MODE_TOP2FWD ) { int pair = 1 << ia | 1 << ib; if ( pair != 0x9 && pair != 0x6 ) // unambiguous pair: A/C or A/G { if ( ir==ia ) return ret; int ia_rev = revint(ia); if ( ir==ia_rev ) // vcfref is A, faref is T, flip { args.dirty = FIX_FLIP; args.nflip++; return set_ref_alt(&args,rec,int2nt(ia_rev),int2nt(revint(ib)),0); } if ( ir==ib ) // vcfalt is faref, swap { args.dirty = FIX_SWAP|FIX_GT; args.nswap++; return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),1); } if ( ib!=revint(ir) ) { args.dirty = FIX_ERR; args.nerr++; return ret; } args.dirty = FIX_FLIP|FIX_SWAP|FIX_GT; args.nflip_swap++; return set_ref_alt(&args,rec,int2nt(revint(ib)),int2nt(revint(ia)),1); } else // ambiguous pair, sequence walking must be performed { int len, win = rec->pos > 100 ? 100 : rec->pos, beg = rec->pos - win, end = rec->pos + win; char *ref = faidx_fetch_seq(args.fai, (char*)bcf_seqname(args.hdr_in,rec), beg,end, &len); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", bcf_seqname(args.hdr_in,rec),(int64_t) rec->pos+1); if ( end - beg + 1 != len ) error("FIXME: check win=%d,len=%d at %s:%"PRId64" (%d %d)\n", win,len, bcf_seqname(args.hdr_in,rec),(int64_t) rec->pos+1, end,beg); int i, mid = rec->pos - beg, strand = 0; for (i=1; i<=win; i++) { int ra = nt2int(ref[mid-i]); int rb = nt2int(ref[mid+i]); if ( ra<0 || rb<0 || ra==rb ) continue; // skip N's and non-infomative pairs: A/A, C/C, G/G, T/T pair = 1 << ra | 1 << rb; if ( pair==0x9 || pair==0x6 ) continue; // skip ambiguous pairs: A/T or C/G strand = 1 << ra & 0x9 ? 1 : -1; break; } free(ref); if ( strand==1 ) { if ( ir==ia ) { args.dirty = FIX_NONE; return ret; } if ( ir==ib ) { args.dirty = FIX_SWAP|FIX_GT; args.nswap++; return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),1); } } else if ( strand==-1 ) { int ia_rev = revint(ia); int ib_rev = revint(ib); if ( ir==ia_rev ) { args.dirty = FIX_FLIP; args.nflip++; return set_ref_alt(&args,rec,int2nt(ia_rev),int2nt(ib_rev),0); } if ( ir==ib_rev ) { args.dirty = FIX_FLIP|FIX_SWAP|FIX_GT; args.nflip_swap++; return set_ref_alt(&args,rec,int2nt(ib_rev),int2nt(ia_rev),1); } } args.nunresolved++; return args.discard ? NULL : ret; } } return ret; } bcf1_t *process(bcf1_t *rec) { args.dirty = 0; bcf1_t *ret = process_record(rec); if ( ret && args.dirty ) { args.str.l = 0; int i; for (i=0; i<6; i++) { if ( !(args.dirty & (1<%c\t%u\t%.1f%%\n", int2nt(i),int2nt(j),args.count[i][j], args.count[i][j]*100./tot); } } fprintf(stderr,"# NS, Number of sites:\n"); fprintf(stderr,"NS\ttotal \t%u\n", args.nsite); fprintf(stderr,"NS\tref match \t%u\t%.1f%%\n", args.nok,100.*args.nok/ncmp); fprintf(stderr,"NS\tref mismatch \t%u\t%.1f%%\n", ncmp-args.nok,100.*(ncmp-args.nok)/ncmp); if ( args.mode!=MODE_STATS ) { fprintf(stderr,"NS\tflipped \t%u\t%.1f%%\n", args.nflip,100.*args.nflip/(args.nsite-nskip)); fprintf(stderr,"NS\tswapped \t%u\t%.1f%%\n", args.nswap,100.*args.nswap/(args.nsite-nskip)); fprintf(stderr,"NS\tflip+swap \t%u\t%.1f%%\n", args.nflip_swap,100.*args.nflip_swap/(args.nsite-nskip)); fprintf(stderr,"NS\tunresolved \t%u\t%.1f%%\n", args.nunresolved,100.*args.nunresolved/(args.nsite-nskip)); fprintf(stderr,"NS\tfixed pos \t%u\t%.1f%%\n", args.npos_err,100.*args.npos_err/(args.nsite-nskip)); } fprintf(stderr,"NS\terrors \t%u\n", args.nerr); fprintf(stderr,"NS\tskipped \t%u\n", nskip); fprintf(stderr,"NS\tnon-ACGT \t%u\n", args.nonACGT); fprintf(stderr,"NS\tnon-SNP \t%u\n", args.nonSNP); fprintf(stderr,"NS\tnon-biallelic\t%u\n", args.nonbiallelic); free(args.str.s); free(args.gts); if ( args.fai ) fai_destroy(args.fai); dbsnp_destroy(&args); } bcftools-1.21/plugins/frameshifts.c000066400000000000000000000113711467060157400174250ustar00rootroot00000000000000/* plugins/frameshifts.c -- annotates frameshift indels. Copyright (C) 2014 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include bcf_hdr_t *in_hdr, *out_hdr; bcf_sr_regions_t *exons; int32_t *frm = NULL, nfrm = 0; const char *about(void) { return "Annotate frameshift indels.\n"; } const char *usage(void) { return "\n" "About: Annotate frameshift indels\n" "Usage: bcftools +frameshifts [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -e, --exons list of exons, see \"--targets-file\" man page entry for details\n" "\n" "Example:\n" " bcftools +frameshifts in.vcf -- -e exons.bed.gz\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { int c; char *fname = NULL; static struct option loptions[] = { {"exons",1,0,'e'}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "e:?h",loptions,NULL)) >= 0) { switch (c) { case 'e': fname = optarg; break; case 'h': case '?': default: fprintf(stderr,"%s", usage()); exit(1); break; } } if ( !fname ) { fprintf(stderr,"Missing the -e option.\n"); return -1; } in_hdr = in; out_hdr = out; int ret = bcf_hdr_append(out_hdr,"##INFO="); if ( ret!=0 ) { fprintf(stderr,"Error updating the header\n"); return -1; } exons = bcf_sr_regions_init(fname,1,0,1,2); if ( !exons ) { fprintf(stderr,"Error occurred while reading (was the file compressed with bgzip?): %s\n", fname); return -1; } return 0; } bcf1_t *process(bcf1_t *rec) { if ( rec->n_allele<2 ) return rec; // not a variant int type = bcf_get_variant_types(rec); if ( !(type&VCF_INDEL) ) return rec; // not an indel int i, len = 0; for (i=1; in_allele; i++) if ( len > rec->d.var[i].n ) len = rec->d.var[i].n; int pos_to = len!=0 ? rec->pos : rec->pos - len; // len is negative if ( bcf_sr_regions_overlap(exons, bcf_seqname(in_hdr,rec),rec->pos,pos_to) ) return rec; // no overlap hts_expand(int32_t,rec->n_allele-1,nfrm,frm); for (i=1; in_allele; i++) { if ( rec->d.var[i].type!=VCF_INDEL ) { frm[i-1] = -1; continue; } int len = rec->d.var[i].n, tlen = 0; if ( len>0 ) { // insertion if ( exons->start <= rec->pos && exons->end > rec->pos ) tlen = abs(len); } else if ( exons->start <= rec->pos + abs(len) ) { // deletion tlen = abs(len); if ( rec->pos < exons->start ) // trim the beginning tlen -= exons->start - rec->pos + 1; if ( exons->end < rec->pos + abs(len) ) // trim the end tlen -= rec->pos + abs(len) - exons->end; } if ( tlen ) // there are some deleted/inserted bases in the exon { if ( tlen%3 ) frm[i-1] = 1; // out-of-frame else frm[i-1] = 0; // in-frame } else frm[i-1] = -1; // not applicable (is outside) } if ( bcf_update_info_int32(out_hdr,rec,"OOF",frm,rec->n_allele-1)<0 ) { fprintf(stderr, "Could not annotate OOF :-/\n"); exit(1); } return rec; } void destroy(void) { bcf_sr_regions_destroy(exons); } bcftools-1.21/plugins/guess-ploidy.c000066400000000000000000000550441467060157400175430ustar00rootroot00000000000000/* Copyright (C) 2016-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define GUESS_GT 1 #define GUESS_PL 2 #define GUESS_GL 4 typedef struct { uint64_t ncount; double phap, pdip; } count_t; typedef struct { char *chr; uint32_t start, end; count_t *counts; // per-sample counts: counts[isample] } stats_t; typedef struct { int argc; char **argv, *af_tag; double af_dflt; stats_t stats; filter_t *filter; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE const uint8_t *smpl_pass; int nsample, verbose, tag, include_indels; int *counts, ncounts; // number of observed GTs with given ploidy, used when -g is not given double *tmpf, *pl2p, gt_err_prob; float *af; int maf; int32_t *arr, narr, nfarr; float *farr; bcf_srs_t *sr; bcf_hdr_t *hdr; } args_t; const char *about(void) { return "Determine sample sex by checking genotype likelihoods in haploid regions.\n"; } static const char *usage_text(void) { return "\n" "About: Determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT)\n" " in the non-PAR region of chrX. The HWE is assumed, so given the alternate allele\n" " frequency fA and the genotype likelihoods pRR,pRA,pAA, the probabilities are\n" " calculated as\n" " P(dip) = pRR*(1-fA)^2 + pAA*fA^2 + 2*pRA*(1-fA)*fA\n" " P(hap) = pRR*(1-fA) + pAA*fA\n" " When genotype likelihoods are not available, the -e option is used to account\n" " for genotyping errors with -t GT. The alternate allele frequency fA is estimated\n" " directly from the data (the default) or can be provided by an INFO tag.\n" " The results can be visualized using the accompanied guess-ploidy.py script.\n" " Note that this plugin is intended to replace the former vcf2sex plugin.\n" "\n" "Usage: bcftools +guess-ploidy [Plugin Options]\n" "Plugin options:\n" " --AF-dflt the default alternate allele frequency [0.5]\n" " --AF-tag use TAG for allele frequency\n" " -e, --error-rate probability of GT being wrong (with -t GT) [1e-3]\n" " --exclude exclude sites for which the expression is true\n" " -i, --include-indels do not skip indel sites\n" " --include include only sites for which the expression is true\n" " -g, --genome shortcut to select nonPAR region for common genomes b37|hg19|b38|hg38\n" " -r, --regions restrict to comma-separated list of regions\n" " -R, --regions-file restrict to regions listed in a file\n" " -t, --tag genotype or genotype likelihoods: GT, PL, GL [PL]\n" " -v, --verbose verbose output (specify twice to increase verbosity)\n" "\n" "Region shortcuts:\n" " b37 .. -r X:2699521-154931043 # GRCh37 no-chr prefix\n" " b38 .. -r X:2781480-155701381 # GRCh38 no-chr prefix\n" " hg19 .. -r chrX:2699521-154931043 # GRCh37 chr prefix\n" " hg38 .. -r chrX:2781480-155701381 # GRCh38 chr prefix\n" "\n" "Examples:\n" " bcftools +guess-ploidy -g b37 in.vcf.gz\n" " bcftools +guess-ploidy in.vcf.gz -t GL -r chrX:2699521-154931043\n" " bcftools view file.vcf.gz -r chrX:2699521-154931043 | bcftools +guess-ploidy\n" " bcftools +guess-ploidy in.bcf -v > ploidy.txt && guess-ploidy.py ploidy.txt img\n" "\n"; } static inline int smpl_pass(args_t *args, int ismpl) { if ( !args->smpl_pass ) return 1; int pass = args->smpl_pass[ismpl]; if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( pass ) return 1; return 0; } void process_region_guess(args_t *args) { while ( bcf_sr_next_line(args->sr) ) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( rec->n_allele==1 ) continue; if ( !args->include_indels && !(bcf_get_variant_types(rec)&VCF_SNP) ) continue; if ( args->filter ) { int pass = filter_test(args->filter, rec, &args->smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !args->smpl_pass && !pass ) continue; // site-level filtering, not per-sample filtering } double freq[2] = {0,0}, sum; int ismpl,i; if ( args->tag & GUESS_GT ) // use GTs to guess the ploidy, considering only one ALT { int ngt = bcf_get_genotypes(args->hdr,rec,&args->arr,&args->narr); if ( ngt<=0 ) continue; ngt /= args->nsample; for (ismpl=0; ismplnsample; ismpl++) { if ( !smpl_pass(args,ismpl) ) continue; int32_t *ptr = args->arr + ismpl*ngt; double *tmp = args->tmpf + ismpl*3; if ( ptr[0]==bcf_gt_missing ) { tmp[0] = -1; continue; } if ( ptr[1]==bcf_int32_vector_end ) { if ( bcf_gt_allele(ptr[0])==0 ) // haploid R { tmp[0] = 1 - 2*args->gt_err_prob; tmp[1] = tmp[2] = args->gt_err_prob; } else // haploid A { tmp[0] = tmp[1] = args->gt_err_prob; tmp[2] = 1 - 2*args->gt_err_prob; } continue; } if ( bcf_gt_allele(ptr[0])==0 && bcf_gt_allele(ptr[1])==0 ) // RR { tmp[0] = 1 - 2*args->gt_err_prob; tmp[1] = tmp[2] = args->gt_err_prob; } else if ( bcf_gt_allele(ptr[0])==bcf_gt_allele(ptr[1]) ) // AA { tmp[0] = tmp[1] = args->gt_err_prob; tmp[2] = 1 - 2*args->gt_err_prob; } else // RA or hetAA, treating as RA { tmp[1] = 1 - 2*args->gt_err_prob; tmp[0] = tmp[2] = args->gt_err_prob; } freq[0] += 2*tmp[0]+tmp[1]; freq[1] += tmp[1]+2*tmp[2]; } } else if ( args->tag & GUESS_PL ) // use PL guess the ploidy, restrict to first ALT allele { int npl = bcf_get_format_int32(args->hdr,rec,"PL",&args->arr,&args->narr); if ( npl<=0 ) continue; npl /= args->nsample; int ndip_gt = rec->n_allele*(rec->n_allele+1)/2; if ( npl==ndip_gt ) // diploid { for (ismpl=0; ismplnsample; ismpl++) { if ( !smpl_pass(args,ismpl) ) continue; int32_t *ptr = args->arr + ismpl*npl; double *tmp = args->tmpf + ismpl*3; // restrict to first ALT if ( ptr[0]==bcf_int32_missing || ptr[1]==bcf_int32_missing || ptr[2]==bcf_int32_missing ) { tmp[0] = -1; continue; } if ( ptr[0]==ptr[1] && ptr[0]==ptr[2] ) // non-informative { tmp[0] = -1; continue; } if ( ptr[2]==bcf_int32_vector_end ) { tmp[0] = (ptr[0]<0 || ptr[0]>=256) ? args->pl2p[255] : args->pl2p[ptr[0]]; tmp[1] = args->pl2p[255]; tmp[2] = (ptr[1]<0 || ptr[1]>=256) ? args->pl2p[255] : args->pl2p[ptr[1]]; } else for (i=0; i<3; i++) tmp[i] = (ptr[i]<0 || ptr[i]>=256) ? args->pl2p[255] : args->pl2p[ptr[i]]; sum = 0; for (i=0; i<3; i++) sum += tmp[i]; for (i=0; i<3; i++) tmp[i] /= sum; if ( ptr[2]==bcf_int32_vector_end ) { freq[0] += tmp[0]; freq[1] += tmp[2]; } else { freq[0] += 2*tmp[0]+tmp[1]; freq[1] += tmp[1]+2*tmp[2]; } } } else if ( npl==rec->n_allele ) // all samples haploid { for (ismpl=0; ismplnsample; ismpl++) { if ( !smpl_pass(args,ismpl) ) continue; int32_t *ptr = args->arr + ismpl*npl; double *tmp = args->tmpf + ismpl*3; // restrict to first ALT if ( ptr[0]==bcf_int32_missing || ptr[1]==bcf_int32_missing ) { tmp[0] = -1; continue; } tmp[0] = (ptr[0]<0 || ptr[0]>=256) ? args->pl2p[255] : args->pl2p[ptr[0]]; tmp[1] = args->pl2p[255]; tmp[2] = (ptr[1]<0 || ptr[1]>=256) ? args->pl2p[255] : args->pl2p[ptr[1]]; sum = 0; for (i=0; i<3; i++) sum += tmp[i]; for (i=0; i<3; i++) tmp[i] /= sum; freq[0] += tmp[0]; freq[1] += tmp[2]; } } else continue; // neither diploid nor haploid } else // use GL { int ngl = bcf_get_format_float(args->hdr,rec,"GL",&args->farr,&args->nfarr); if ( ngl<=0 ) continue; ngl /= args->nsample; int ndip_gt = rec->n_allele*(rec->n_allele+1)/2; if ( ngl==ndip_gt ) // diploid { for (ismpl=0; ismplnsample; ismpl++) { if ( !smpl_pass(args,ismpl) ) continue; float *ptr = args->farr + ismpl*ngl; double *tmp = args->tmpf + ismpl*3; // restrict to first ALT if ( bcf_float_is_missing(ptr[0]) || bcf_float_is_missing(ptr[1]) || bcf_float_is_missing(ptr[2]) ) { tmp[0] = -1; continue; } if ( ptr[0]==ptr[1] && ptr[0]==ptr[2] ) // non-informative { tmp[0] = -1; continue; } if ( bcf_float_is_vector_end(ptr[2]) ) { tmp[0] = pow(10.,ptr[0]); tmp[1] = 1e-26; // arbitrary small value for a het tmp[2] = pow(10.,ptr[1]); } else for (i=0; i<3; i++) tmp[i] = pow(10.,ptr[i]); sum = 0; for (i=0; i<3; i++) sum += tmp[i]; for (i=0; i<3; i++) tmp[i] /= sum; if ( bcf_float_is_vector_end(ptr[2]) ) { freq[0] += tmp[0]; freq[1] += tmp[2]; } else { freq[0] += 2*tmp[0]+tmp[1]; freq[1] += tmp[1]+2*tmp[2]; } } } else if ( ngl==rec->n_allele ) // all samples haploid { for (ismpl=0; ismplnsample; ismpl++) { if ( !smpl_pass(args,ismpl) ) continue; float *ptr = args->farr + ismpl*ngl; double *tmp = args->tmpf + ismpl*3; // restrict to first ALT if ( bcf_float_is_missing(ptr[0]) || bcf_float_is_missing(ptr[1]) ) { tmp[0] = -1; continue; } tmp[0] = pow(10.,ptr[0]); tmp[1] = 1e-26; tmp[2] = pow(10.,ptr[1]); sum = 0; for (i=0; i<3; i++) sum += tmp[i]; for (i=0; i<3; i++) tmp[i] /= sum; freq[0] += tmp[0]; freq[1] += tmp[2]; } } else continue; // neither diploid nor haploid } if ( args->af_tag ) { int ret = bcf_get_info_float(args->hdr,rec,args->af_tag,&args->af, &args->maf); if ( ret>0 ) { freq[0] = 1 - args->af[0]; freq[1] = args->af[0]; } } if ( !freq[0] && !freq[1] ) { freq[0] = 1 - args->af_dflt; freq[1] = args->af_dflt; } sum = freq[0] + freq[1]; freq[0] /= sum; freq[1] /= sum; for (ismpl=0; ismplnsample; ismpl++) { if ( !smpl_pass(args,ismpl) ) continue; count_t *counts = &args->stats.counts[ismpl]; double *tmp = args->tmpf + ismpl*3; if ( tmp[0] < 0 ) continue; double phap = freq[0]*tmp[0] + freq[1]*tmp[2]; double pdip = freq[0]*freq[0]*tmp[0] + 2*freq[0]*freq[1]*tmp[1] + freq[1]*freq[1]*tmp[2]; counts->phap += log(phap); counts->pdip += log(pdip); counts->ncount++; if ( args->verbose>1 ) printf("DBG\t%s\t%"PRId64"\t%s\t%e\t%e\t%e\t%e\t%e\t%e\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,ismpl), freq[1],tmp[0],tmp[1],tmp[2],phap,pdip); } } } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->tag = GUESS_PL; args->argc = argc; args->argv = argv; args->gt_err_prob = 1e-3; args->af_dflt = 0.5; char *region = NULL; int region_is_file = 0; static struct option loptions[] = { {"AF-tag",required_argument,NULL,0}, {"AF-dflt",required_argument,NULL,1}, {"exclude",required_argument,NULL,2}, {"include",required_argument,NULL,3}, {"verbose",no_argument,NULL,'v'}, {"include-indels",no_argument,NULL,'i'}, {"error-rate",required_argument,NULL,'e'}, {"tag",required_argument,NULL,'t'}, {"genome",required_argument,NULL,'g'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"background",required_argument,NULL,'b'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "vr:R:t:e:ig:",loptions,NULL)) >= 0) { switch (c) { case 0: args->af_tag = optarg; break; case 1: args->af_dflt = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --AF-dflt %s\n", optarg); break; case 2: if ( args->filter_str ) error("Error: only one --include or --exclude expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 3: if ( args->filter_str ) error("Error: only one --include or --exclude expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'i': args->include_indels = 1; break; case 'e': args->gt_err_prob = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -e %s\n", optarg); if ( args->gt_err_prob<0 || args->gt_err_prob>1 ) error("Expected value from the interval [0,1]: -e %s\n", optarg); break; case 'g': if ( !strcasecmp(optarg,"b37") ) region = "X:2699521-154931043"; else if ( !strcasecmp(optarg,"b38") ) region = "X:2781480-155701381"; else if ( !strcasecmp(optarg,"hg19") ) region = "chrX:2699521-154931043"; else if ( !strcasecmp(optarg,"hg38") ) region = "chrX:2781480-155701381"; else error("The argument not recognised, expected --genome b37, b38, hg19 or hg38: %s\n", optarg); break; case 'R': region_is_file = 1; // fall-through case 'r': region = optarg; break; case 'v': args->verbose++; break; case 't': if ( !strcasecmp(optarg,"GT") ) args->tag = GUESS_GT; else if ( !strcasecmp(optarg,"PL") ) args->tag = GUESS_PL; else if ( !strcasecmp(optarg,"GL") ) args->tag = GUESS_GL; else error("The argument not recognised, expected --tag GT, PL or GL: %s\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of --include or --exclude can be given.\n"); char *fname = NULL; if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else fname = argv[optind]; args->sr = bcf_sr_init(); if ( strcmp("-",fname) ) { if ( region ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, region, region_is_file)<0 ) error("Failed to read the regions: %s\n",region); } } else { if ( region ) { if ( bcf_sr_set_targets(args->sr, region, region_is_file, 0)<0 ) error("Failed to read the targets: %s\n",region); } } if ( !bcf_sr_add_reader(args->sr,fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = args->sr->readers[0].header; args->nsample = bcf_hdr_nsamples(args->hdr); args->stats.counts = (count_t*) calloc(args->nsample,sizeof(count_t)); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); if ( args->af_tag && !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_INFO,bcf_hdr_id2int(args->hdr,BCF_DT_ID,args->af_tag)) ) error("No such INFO tag: %s\n", args->af_tag); if ( args->tag&GUESS_PL && bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL")<0 ) { fprintf(stderr, "Warning: PL tag not found in header, switching to GL\n"); args->tag = GUESS_GL; } if ( args->tag&GUESS_GL && bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GL")<0 ) { fprintf(stderr, "Warning: GL tag not found in header, switching to GT\n"); args->tag = GUESS_GT; } if ( args->tag&GUESS_GT && bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT")<0 ) error("Error: GT tag not found in header\n"); int i; if ( args->tag&GUESS_PL ) { args->pl2p = (double*) calloc(256,sizeof(double)); for (i=0; i<256; i++) args->pl2p[i] = pow(10., -i/10.); } if ( args->tag&GUESS_PL || args->tag&GUESS_GL || args->tag&GUESS_GT ) args->tmpf = (double*) malloc(sizeof(*args->tmpf)*3*args->nsample); if ( args->verbose ) { printf("# This file was produced by: bcftools +guess-ploidy(%s+htslib-%s)\n", bcftools_version(),hts_version()); printf("# The command line was:\tbcftools +%s", args->argv[0]); for (i=1; iargc; i++) printf(" %s",args->argv[i]); printf("\n"); printf("# [1]SEX\t[2]Sample\t[3]Predicted sex\t[4]log P(Haploid)/nSites\t[5]log P(Diploid)/nSites\t[6]nSites\t[7]Score: F < 0 < M ($4-$5)\n"); if ( args->verbose>1 ) printf("# [1]DBG\t[2]Chr\t[3]Pos\t[4]Sample\t[5]AF\t[6]pRR\t[7]pRA\t[8]pAA\t[9]P(Haploid)\t[10]P(Diploid)\n"); } process_region_guess(args); for (i=0; insample; i++) { double phap = args->stats.counts[i].ncount ? args->stats.counts[i].phap / args->stats.counts[i].ncount : 0.5; double pdip = args->stats.counts[i].ncount ? args->stats.counts[i].pdip / args->stats.counts[i].ncount : 0.5; char predicted_sex = 'U'; if (phap>pdip) predicted_sex = 'M'; else if (phapverbose ) { printf("SEX\t%s\t%c\t%f\t%f\t%"PRId64"\t%f\n", args->hdr->samples[i],predicted_sex, phap,pdip,args->stats.counts[i].ncount,phap-pdip); } else printf("%s\t%c\n", args->hdr->samples[i],predicted_sex); } if ( args->filter ) filter_destroy(args->filter); bcf_sr_destroy(args->sr); free(args->pl2p); free(args->tmpf); free(args->counts); free(args->stats.counts); free(args->arr); free(args->farr); free(args->af); free(args); return 0; } bcftools-1.21/plugins/gvcfz.c000066400000000000000000000374021467060157400162340ustar00rootroot00000000000000/* Copyright (C) 2017-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Compress gVCF file by resizing gVCF blocks according to specified criteria. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define GQ_KEY_NONE NULL #define GQ_KEY_GQ "GQ" #define GQ_KEY_RGQ "RGQ" typedef struct { int32_t end, min_dp, gq, pl[3], grp; char *gq_key; bcf1_t *rec; } block_t; typedef struct { char *expr; // expression int flt_id; // filter id, -1 for PASS filter_t *flt; // filter } grp_t; typedef struct { filter_t *filter; char *filter_str; int filter_logic; block_t gvcf; htsFile *fh_out; int ngrp; grp_t *grp; char *group_by; int argc, region_is_file, target_is_file, output_type, trim_alts, clevel; int32_t *tmpi, mtmpi, mean_min_dp_reported; char **argv, *region, *target, *fname, *output_fname, *keep_tags; bcf_hdr_t *hdr_in, *hdr_out; bcf_srs_t *sr; char *index_fn; int write_index; } args_t; const char *about(void) { return "Compress gVCF file by resizing gVCF blocks according to specified criteria.\n"; } static const char *usage_text(void) { return "\n" "About: Compress gVCF file by resizing gVCF blocks according to specified criteria.\n" "\n" "Usage: bcftools +gvcfz [Options]\n" "Plugin options:\n" " -a, --trim-alt-alleles Trim alternate alleles not seen in the genotypes\n" " -e, --exclude Exclude sites for which the expression is true\n" " -i, --include Include sites for which the expression is true\n" " -g, --group-by EXPR Group gVCF blocks according to the expression\n" " -o, --output FILE Write gVCF output to the FILE\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "Examples:\n" " # Compress blocks by GQ and DP. Multiple blocks separated by a semicolon can be defined\n" " bcftools +gvcfz input.bcf -g'PASS:GQ>60 & DP<20; PASS:GQ>40 & DP<15; Flt1:QG>20; Flt2:-'\n" "\n" " # Compress all non-reference sites into a single block, remove unused alternate alleles\n" " bcftools +gvcfz input.bcf -a -g'PASS:GT!=\"alt\"'\n" "\n"; } static void init_groups(args_t *args) { args->hdr_out = bcf_hdr_dup(args->hdr_in); bcf_hdr_printf(args->hdr_out, "##INFO="); // avoid nested double quotes in FILTER description char *hdr_str = strdup(args->group_by); char *tmp = hdr_str; while (*tmp) { if ( *tmp=='"' ) *tmp = '\''; tmp++; } char *rmme_str = strdup(args->group_by), *beg = rmme_str; while ( *beg ) { while ( *beg && isspace(*beg) ) beg++; if ( !beg ) break; char *end = beg; while ( *end && *end!=':' ) end++; if ( *end!=':' ) error("Could not parse the expression: \"%s\"\n", args->group_by); *end = 0; char *flt = beg; beg = ++end; while ( *end && *end!=';' ) end++; char tmp = *end; *end = 0; if ( strcmp(flt,"PASS") ) { bcf_hdr_printf(args->hdr_out, "##FILTER=", flt, hdr_str); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); } args->ngrp++; args->grp = (grp_t*) realloc(args->grp,sizeof(grp_t)*args->ngrp); grp_t *grp = args->grp + args->ngrp - 1; grp->expr = strdup(beg); grp->flt_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, flt); if ( !bcf_hdr_idinfo_exists(args->hdr_out, BCF_HL_FLT, grp->flt_id) ) error("Could not initialize the filter \"%s\"\n", flt); if ( !strcmp(flt,"PASS") ) grp->flt_id = -1; // remove trailing spaces beg = grp->expr + strlen(grp->expr); while ( beg >= grp->expr && isspace(*beg) ) { *beg = 0; beg--; } beg = grp->expr; while ( *beg && isspace(*beg) ) beg++; grp->flt = strcmp("-",beg) ? filter_init(args->hdr_in, grp->expr) : NULL; if ( !tmp ) break; beg = end + 1; } free(rmme_str); free(hdr_str); } static void destroy_data(args_t *args) { int i; for (i=0; ingrp; i++) { if ( args->grp[i].flt ) filter_destroy(args->grp[i].flt); free(args->grp[i].expr); } free(args->grp); if ( args->filter ) filter_destroy(args->filter); if ( args->write_index ) { if ( bcf_idx_save(args->fh_out)<0 ) { if ( hts_close(args->fh_out)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->fh_out)!=0 ) error("failed to close %s\n", args->output_fname); bcf_sr_destroy(args->sr); if ( args->hdr_out ) bcf_hdr_destroy(args->hdr_out); if ( args->gvcf.rec ) bcf_destroy(args->gvcf.rec); free(args->tmpi); free(args); } static void flush_block(args_t *args, bcf1_t *rec) { block_t *gvcf = &args->gvcf; if ( gvcf->grp < 0 ) return; if ( rec && gvcf->end - 1 >= rec->pos ) gvcf->end = rec->pos; // NB: end is 1-based, rec->pos is 0-based if ( gvcf->rec->pos+1 < gvcf->end && bcf_update_info_int32(args->hdr_out,gvcf->rec,"END",&gvcf->end,1) != 0 ) error("Could not update INFO/END at %s:%"PRId64"\n", bcf_seqname(args->hdr_out,gvcf->rec),(int64_t) gvcf->rec->pos+1); if ( bcf_update_format_int32(args->hdr_out,gvcf->rec,"DP",&gvcf->min_dp,1) != 0 ) error("Could not update FORMAT/DP at %s:%"PRId64"\n", bcf_seqname(args->hdr_out,gvcf->rec),(int64_t) gvcf->rec->pos+1); if ( gvcf->gq_key ) { if ( bcf_update_format_int32(args->hdr_out,gvcf->rec,gvcf->gq_key,&gvcf->gq,1) != 0 ) error("Could not update FORMAT/%s at %s:%"PRId64"\n", gvcf->gq_key, bcf_seqname(args->hdr_out,gvcf->rec),(int64_t) gvcf->rec->pos+1); } if ( gvcf->pl[0] >=0 ) { if ( bcf_update_format_int32(args->hdr_out,gvcf->rec,"PL",&gvcf->pl,3) != 0 ) error("Could not update FORMAT/PL at %s:%"PRId64"\n", bcf_seqname(args->hdr_out,gvcf->rec),(int64_t) gvcf->rec->pos+1); } if ( gvcf->grp < args->ngrp && args->grp[gvcf->grp].flt_id >= 0 ) bcf_add_filter(args->hdr_out, gvcf->rec, args->grp[gvcf->grp].flt_id); if ( bcf_write(args->fh_out, args->hdr_out, gvcf->rec)!=0 ) error("Failed to write the header\n"); gvcf->grp = -1; } static void process_gvcf(args_t *args) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( args->filter ) { int pass = filter_test(args->filter, rec, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) return; } if ( rec->n_allele > 2 || (rec->n_allele == 2 && strcmp("",rec->d.allele[1]) && strcmp("<*>",rec->d.allele[1])) ) { if ( args->trim_alts ) { bcf_unpack(rec, BCF_UN_ALL); if ( bcf_trim_alleles(args->hdr_in, rec)<0 ) error("Error: Could not trim alleles at %s:%"PRId64"\n", bcf_seqname(args->hdr_in, rec),(int64_t) rec->pos+1); // trim the ref allele if necessary if ( rec->d.allele[0][1] ) { rec->d.allele[0][1] = 0; bcf_update_alleles(args->hdr_in, rec, (const char**)rec->d.allele, 1); } } if ( rec->n_allele > 2 || (rec->n_allele == 2 && strcmp("",rec->d.allele[1]) && strcmp("<*>",rec->d.allele[1])) ) { // not a gvcf block flush_block(args, rec); if ( bcf_write(args->fh_out, args->hdr_out, rec)!=0 ) error("Failed to write\n"); return; } } int ret = bcf_get_info_int32(args->hdr_in,rec,"END",&args->tmpi,&args->mtmpi); int32_t end = ret==1 ? args->tmpi[0] : rec->pos + 1; char *gq_key = GQ_KEY_GQ; ret = bcf_get_format_int32(args->hdr_in,rec,gq_key,&args->tmpi,&args->mtmpi); if ( ret!=1 ) { gq_key = GQ_KEY_RGQ; if ( ret<1 ) ret = bcf_get_format_int32(args->hdr_in,rec,gq_key,&args->tmpi,&args->mtmpi); if ( ret!=1 ) gq_key = GQ_KEY_NONE; } int32_t gq = ret==1 ? args->tmpi[0] : 0; int32_t min_dp = 0; if ( bcf_get_format_int32(args->hdr_in,rec,"MIN_DP",&args->tmpi,&args->mtmpi)==1 ) min_dp = args->tmpi[0]; else if ( bcf_get_format_int32(args->hdr_in,rec,"DP",&args->tmpi,&args->mtmpi)==1 ) min_dp = args->tmpi[0]; else error("Expected one FORMAT/MIN_DP or FORMAT/DP value at %s:%"PRId64"\n", bcf_seqname(args->hdr_in,rec),(int64_t) rec->pos+1); int32_t pl[3] = {-1,-1,-1}; ret = bcf_get_format_int32(args->hdr_in,rec,"PL",&args->tmpi,&args->mtmpi); if ( ret>3 ) error("Expected three FORMAT/PL values at %s:%"PRId64"\n", bcf_seqname(args->hdr_in,rec),(int64_t) rec->pos+1); else if ( ret==3 ) { pl[0] = args->tmpi[0]; pl[1] = args->tmpi[1]; pl[2] = args->tmpi[2]; } int i; for (i=0; ingrp; i++) if ( !args->grp[i].flt || filter_test(args->grp[i].flt, rec, NULL)==1 ) break; if ( args->gvcf.grp != i ) flush_block(args, rec); // new block if ( args->gvcf.grp >= 0 && args->gvcf.rec->rid != rec->rid ) flush_block(args, NULL); // new chromosome if ( args->gvcf.grp >= 0 ) // extend an existing block { if ( args->gvcf.end < end ) args->gvcf.end = end; if ( args->gvcf.gq_key!=GQ_KEY_NONE && gq_key!=GQ_KEY_NONE && args->gvcf.gq > gq ) args->gvcf.gq = gq; if ( args->gvcf.min_dp > min_dp ) args->gvcf.min_dp = min_dp; if ( args->gvcf.pl[0] > pl[0] ) args->gvcf.pl[0] = pl[0]; if ( args->gvcf.pl[1] > pl[1] ) args->gvcf.pl[1] = pl[1]; if ( args->gvcf.pl[2] > pl[2] ) args->gvcf.pl[2] = pl[2]; return; } // start a new block args->gvcf.rec = bcf_copy(args->gvcf.rec, rec); args->gvcf.grp = i; args->gvcf.min_dp = min_dp; args->gvcf.end = end; args->gvcf.pl[0] = pl[0]; args->gvcf.pl[1] = pl[1]; args->gvcf.pl[2] = pl[2]; args->gvcf.gq_key = gq_key; if ( gq_key!=GQ_KEY_NONE ) args->gvcf.gq = gq; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->output_fname = "-"; args->clevel = -1; static struct option loptions[] = { {"trim-alt-alleles",required_argument,0,'a'}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"group-by",required_argument,NULL,'g'}, {"stats",required_argument,NULL,'s'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "vr:R:t:T:o:O:g:i:e:aW::",loptions,NULL)) >= 0) { switch (c) { case 'a': args->trim_alts = 1; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'g': args->group_by = optarg; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->group_by ) error("Missing the -g option\n"); args->gvcf.rec = bcf_init(); args->gvcf.grp = -1; // the block is inactive args->sr = bcf_sr_init(); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr_in = bcf_sr_get_header(args->sr,0); if ( args->filter_str ) args->filter = filter_init(args->hdr_in, args->filter_str); init_groups(args); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->fh_out = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( bcf_hdr_write(args->fh_out, args->hdr_out)!=0 ) error("Failed to write the header\n"); if ( init_index2(args->fh_out,args->hdr_out,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); while ( bcf_sr_next_line(args->sr) ) process_gvcf(args); flush_block(args, NULL); destroy_data(args); return 0; } bcftools-1.21/plugins/impute-info.c000066400000000000000000000125211467060157400173440ustar00rootroot00000000000000/* plugins/impute-info.c -- adds info metrics to a VCF file. Copyright (C) 2015-2016 Genome Research Ltd. Author: Shane McCarthy Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Marchini & Howie, Nature Genetics, 11 (July 2010) Let G_ij in {0,1,2} be the genotype of the ith individual at the jth SNP in a study cohort of N samples. Let p_ijk = P(G_ij = k | H,G) be the probability that the genotype at the jth SNP of the ith individual is k. Let the expected allele dosage for the genotype at the jth SNP of the ith individual be e_ij = p_ij1 + 2 * p_ij2 and define f_ij = p_ij1 + 4 * p_ij2 Let theta_j denote the (unknown) population allele frequency of the jth SNP with: theta_j = SUM[i=1..N] e_ij / 2 * N The IMPUTE2 information measure is then: if theta_j in (0,1): I(theta_j) = 1 - SUM[i=1..N](f_ij - e_ij^2) / 2 * N * theta_j * (1 - theta_j) else: I(theta_j) = 1 */ #include #include #include #include #include const char *about(void) { return "Add imputation information metrics to the INFO field based on selected FORMAT tags.\n"; } const char *usage(void) { return "\n" "About: Add imputation information metrics to the INFO field based\n" " on selected FORMAT tags. Only the IMPUTE2 INFO metric from\n" " FORMAT/GP tags is currently available.\n" "Usage: bcftools +impute-info [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" // "Plugin options:\n" // " -i, --info information metrics to add [INFO]\n" // [BEAGLE_R2,MACH_R2] // " -t, --tags VCF tags to determine the information from [GP]\n" // "\n" "Example:\n" " bcftools +impute-info in.vcf\n" "\n"; } bcf_hdr_t *in_hdr = NULL, *out_hdr = NULL; int gp_type = BCF_HT_REAL; uint8_t *buf = NULL; int nbuf = 0; // NB: number of elements, not bytes int nrec = 0, nskip_gp = 0, nskip_dip = 0; int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { in_hdr = in; out_hdr = out; bcf_hdr_append(out_hdr,"##INFO="); return 0; } bcf1_t *process(bcf1_t *rec) { int nval = 0, i, j, nret = bcf_get_format_values(in_hdr,rec,"GP",(void**)&buf,&nbuf,gp_type); if ( nret<0 ) { if (!nskip_gp) fprintf(stderr, "[impute-info.c] Warning: info tag not added to sites without GP tag\n"); nskip_gp++; return rec; // require FORMAT/GP tag, return site unchanged } nret /= rec->n_sample; if ( nret != 3 ) { if (!nskip_dip) fprintf(stderr, "[impute-info.c] Warning: info tag not added to sites that are not biallelic diploid\n"); nskip_dip++; return rec; // require biallelic diploid, return site unchanged } double esum = 0, e2sum = 0, fsum = 0; #define BRANCH(type_t,is_missing,is_vector_end) \ { \ type_t *ptr = (type_t*) buf; \ for (i=0; in_sample; i++) \ { \ double vals[3] = {0,0,0}; \ for (j=0; j0 && theta<1) ? (float)(1 - (fsum - e2sum) / (2 * (double)nval * theta * (1.0 - theta))) : 1; bcf_update_info_float(out_hdr, rec, "INFO", &info, 1); nrec++; return rec; } void destroy(void) { fprintf(stderr,"Lines total/info-added/unchanged-no-tag/unchanged-not-biallelic-diploid:\t%d/%d/%d/%d\n", nrec+nskip_gp+nskip_dip, nrec, nskip_gp, nskip_dip); free(buf); } bcftools-1.21/plugins/indel-stats.c000066400000000000000000000721401467060157400173420ustar00rootroot00000000000000/* The MIT License Copyright (c) 2018-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include // for isatty #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 static int NVAF = 20; static int MAX_LEN = 20; static inline int len2bin(int len) { if ( len < -MAX_LEN ) return 0; if ( len > MAX_LEN ) return 2*MAX_LEN; return MAX_LEN + len; } HTS_UNUSED static inline int bin2len(int bin) { return bin - MAX_LEN; } static inline int vaf2bin(float vaf) { return vaf*(NVAF-1); } HTS_UNUSED static inline float bin2vaf(int bin) { return (float)bin/(NVAF-1); } typedef struct { uint32_t *nvaf, // number of indels genotypes with low VAF (<=0.2) and high VAF (>0.2); use vaf2bin and bin2vaf *nlen, // length distribution (-MAX_LEN,MAX_LEN); use len2bin and bin2len; site-wise unless samples are present npass_gt, // number of indel genotypes passing the filter npass, // number of sites passing the filter nsites, // number of sites total nins, ndel, // number of insertions and deletions, site-wise, not genotype-wise nframeshift, ninframe, // site-wise *nfrac; // number of het indels contributing to dfrac double *dfrac; // minor allele fraction at HET indel genotypes, determined from FORMAT/AD } stats_t; typedef struct { stats_t stats; filter_t *filter; char *expr; } flt_stats_t; #define iCHILD 0 #define iFATHER 1 #define iMOTHER 2 typedef struct { int idx[3]; // VCF sample index for father, mother and child int pass; // do all three pass the filters? } trio_t; typedef struct { int argc, filter_logic, regions_is_file, targets_is_file; int nflt_str; char *filter_str, **flt_str; char **argv, *output_fname, *fname, *regions, *targets, *csq_tag, *ped_fname; trio_t *trio; int ntrio, mtrio; bcf_srs_t *sr; bcf_hdr_t *hdr; flt_stats_t *filters; int nfilters, nsmpl; char *csq_str; int32_t *gt_arr, *ad_arr, *ac; int mgt_arr, mad_arr, mac, mcsq_str; int ngt, ngt1, nad, nad1; int allow_alt2ref_DNMs; // is "0/0 0/1 1/1" (child,father,mother) a valid DNM? } args_t; args_t args; const char *about(void) { return "Calculate indel stats scanning over a range of thresholds simultaneously.\n"; } static const char *usage_text(void) { return "\n" "About: Calculates indel stats. Use curly brackets to scan a range of values simultaneously\n" "Usage: bcftools +indel-stats [Plugin Options]\n" "Plugin options:\n" " --alt2ref-DNM consider GT errors such as 0/1 + 1/1 -> 0/0 a valid DNM\n" " -c, --csq-tag STR VEP or BCSQ tag to determine inframe and frameshift variants [CSQ]\n" " -e, --exclude EXPR exclude sites and samples for which the expression is true\n" " -i, --include EXPR include sites and samples for which the expression is true\n" " --max-len INT maximum indel length to consider [20]\n" " --nvaf INT number of variant allele frequency bins [20]\n" " -o, --output FILE output file name [stdout]\n" " -p, --ped FILE limit the stats to de novo indels\n" " -r, --regions REG restrict to comma-separated list of regions\n" " -R, --regions-file FILE restrict to regions listed in a file\n" " -t, --targets REG similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE similar to -R but streams rather than index-jumps\n" "\n" "Example:\n" " bcftools +indel-stats -i 'GQ>{10,20,30,40,50}' file.bcf\n" "\n"; } static void parse_filters(args_t *args) { if ( !args->filter_str ) return; int mflt = 1; args->nflt_str = 1; args->flt_str = (char**) malloc(sizeof(char*)); args->flt_str[0] = strdup(args->filter_str); while (1) { int i, expanded = 0; for (i=args->nflt_str-1; i>=0; i--) { char *exp_beg = strchr(args->flt_str[i], '{'); if ( !exp_beg ) continue; char *exp_end = strchr(exp_beg+1, '}'); if ( !exp_end ) error("Could not parse the expression: %s\n", args->filter_str); char *beg = exp_beg+1, *mid = beg; while ( midflt_str[i], exp_beg - args->flt_str[i], &tmp); kputsn(beg, mid - beg, &tmp); kputs(exp_end+1, &tmp); args->nflt_str++; hts_expand(char*, args->nflt_str, mflt, args->flt_str); args->flt_str[args->nflt_str-1] = tmp.s; beg = ++mid; } expanded = 1; free(args->flt_str[i]); memmove(&args->flt_str[i], &args->flt_str[i+1], (args->nflt_str-i-1)*sizeof(*args->flt_str)); args->nflt_str--; args->flt_str[args->nflt_str] = NULL; } if ( !expanded ) break; } fprintf(stderr,"Collecting data for %d filtering expressions\n", args->nflt_str); } static int cmp_trios(const void *_a, const void *_b) { trio_t *a = (trio_t *) _a; trio_t *b = (trio_t *) _b; int i; int amin = a->idx[0]; for (i=1; i<3; i++) if ( amin > a->idx[i] ) amin = a->idx[i]; int bmin = b->idx[0]; for (i=1; i<3; i++) if ( bmin > b->idx[i] ) bmin = b->idx[i]; if ( amin < bmin ) return -1; if ( amin > bmin ) return 1; return 0; } static void parse_ped(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); kstring_t str = {0,0,0}; if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); int moff = 0, *off = NULL; do { // familyID sampleID paternalID maternalID sex phenotype population relationship siblings secondOrder thirdOrder children comment // BB03 HG01884 HG01885 HG01956 2 0 ACB child 0 0 0 0 int ncols = ksplit_core(str.s,0,&moff,&off); if ( ncols<4 ) error("Could not parse the ped file: %s\n", str.s); int father = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[2]]); if ( father<0 ) continue; int mother = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[3]]); if ( mother<0 ) continue; int child = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); if ( child<0 ) continue; args->ntrio++; hts_expand0(trio_t,args->ntrio,args->mtrio,args->trio); trio_t *trio = &args->trio[args->ntrio-1]; trio->idx[iFATHER] = father; trio->idx[iMOTHER] = mother; trio->idx[iCHILD] = child; } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); fprintf(stderr,"Identified %d complete trios in the VCF file\n", args->ntrio); if ( !args->ntrio ) error("No complete trio identified\n"); // sort the sample by index so that they are accessed more or less sequentially qsort(args->trio,args->ntrio,sizeof(trio_t),cmp_trios); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets && bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); if ( args->ped_fname ) parse_ped(args, args->ped_fname); parse_filters(args); int i; if ( !args->nflt_str ) { args->filters = (flt_stats_t*) calloc(1, sizeof(flt_stats_t)); args->nfilters = 1; args->filters[0].expr = strdup("all"); args->filters[0].stats.nvaf = (uint32_t*) calloc(NVAF, sizeof(uint32_t)); args->filters[0].stats.nlen = (uint32_t*) calloc(MAX_LEN*2+1, sizeof(uint32_t)); args->filters[0].stats.nfrac = (uint32_t*) calloc(MAX_LEN*2+1, sizeof(uint32_t)); args->filters[0].stats.dfrac = (double*) calloc(MAX_LEN*2+1, sizeof(double)); } else { args->nfilters = args->nflt_str; args->filters = (flt_stats_t*) calloc(args->nfilters, sizeof(flt_stats_t)); for (i=0; infilters; i++) { args->filters[i].filter = filter_init(args->hdr, args->flt_str[i]); args->filters[i].expr = strdup(args->flt_str[i]); args->filters[i].stats.nvaf = (uint32_t*) calloc(NVAF, sizeof(uint32_t)); args->filters[i].stats.nlen = (uint32_t*) calloc(MAX_LEN*2+1, sizeof(uint32_t)); args->filters[i].stats.nfrac = (uint32_t*) calloc(MAX_LEN*2+1, sizeof(uint32_t)); args->filters[i].stats.dfrac = (double*) calloc(MAX_LEN*2+1, sizeof(double)); // replace tab's with spaces so that the output stays parsable char *tmp = args->filters[i].expr; while ( *tmp ) { if ( *tmp=='\t' ) *tmp = ' '; tmp++; } } } args->nsmpl = bcf_hdr_nsamples(args->hdr); } static void destroy_data(args_t *args) { int i; for (i=0; infilters; i++) { if ( args->filters[i].filter ) filter_destroy(args->filters[i].filter); free(args->filters[i].stats.nvaf); free(args->filters[i].stats.nlen); free(args->filters[i].stats.nfrac); free(args->filters[i].stats.dfrac); free(args->filters[i].expr); } free(args->filters); for (i=0; inflt_str; i++) free(args->flt_str[i]); free(args->flt_str); bcf_sr_destroy(args->sr); free(args->ac); free(args->trio); free(args->csq_str); free(args->gt_arr); free(args->ad_arr); free(args); } static void report_stats(args_t *args) { int i = 0,j; FILE *fh = !args->output_fname || !strcmp("-",args->output_fname) ? stdout : fopen(args->output_fname,"w"); if ( !fh ) error("Could not open the file for writing: %s\n", args->output_fname); fprintf(fh,"# CMD line shows the command line used to generate this output\n"); fprintf(fh,"# DEF lines define expressions for all tested thresholds\n"); fprintf(fh,"# SN* summary number for every threshold:\n"); fprintf(fh,"# %d) SN*, filter id\n", ++i); fprintf(fh,"# %d) number of samples (or trios with -p)\n", ++i); fprintf(fh,"# %d) number of indel sites total\n", ++i); fprintf(fh,"# %d) number of indel sites that pass the filter (and, with -p, have a de novo indel)\n", ++i); fprintf(fh,"# %d) number of indel genotypes that pass the filter (and, with -p, are de novo)\n", ++i); fprintf(fh,"# %d) number of insertions (site-wise, not genotype-wise)\n", ++i); fprintf(fh,"# %d) number of deletions (site-wise, not genotype-wise)\n", ++i); fprintf(fh,"# %d) number of frameshifts (site-wise, not genotype-wise)\n", ++i); fprintf(fh,"# %d) number of inframe indels (site-wise, not genotype-wise)\n", ++i); fprintf(fh,"#\n"); i = 0; fprintf(fh,"# DVAF* lines report indel variant allele frequency (VAF) distribution for every threshold,\n"); fprintf(fh,"# k-th bin corresponds to the frequency k/(nVAF-1):\n"); fprintf(fh,"# %d) DVAF*, filter id\n", ++i); fprintf(fh,"# %d) nVAF, number of bins which split the [0,1] VAF interval.\n", ++i); fprintf(fh,"# %d-%d) counts of indel genotypes in the VAF bin. For non-reference hets, the VAF of the less supported allele is recorded\n", i+1, i+NVAF); fprintf(fh,"#\n"); i = 0; fprintf(fh,"# DLEN* lines report indel length distribution for every threshold. When genotype fields are available,\n"); fprintf(fh,"# the counts correspond to the number of genotypes, otherwise the number of sites are given.\n"); fprintf(fh,"# The k-th bin corresponds to the indel size k-MAX_LEN, negative for deletions, positive for insertions.\n"); fprintf(fh,"# The first/last bin contains also all deletions/insertions larger than MAX_LEN:\n"); fprintf(fh,"# %d) DLEN*, filter id\n", ++i); fprintf(fh,"# %d) maximum indel length\n", ++i); fprintf(fh,"# %d-%d) counts of indel lengths (-max,..,0,..,max), all unique alleles in a genotype are recorded (alt hets increase the counters 2x, alt homs 1x)\n", i+1, i+MAX_LEN*2+1); fprintf(fh,"#\n"); i = 0; fprintf(fh,"# DFRAC* lines report the mean minor allele fraction at HET indel genotypes as a function of indel size.\n"); fprintf(fh,"# The format is the same as for DLEN:\n"); fprintf(fh,"# %d) DFRAC*, filter id\n", ++i); fprintf(fh,"# %d) maximum indel length\n", ++i); fprintf(fh,"# %d-%d) mean fraction at indel lengths (-max,..,0,..,max)\n", i+1, i+MAX_LEN*2+1); fprintf(fh,"#\n"); i = 0; fprintf(fh,"# NFRAC* lines report the number of indels informing the DFRAC distribution.\n"); fprintf(fh,"# %d) NFRAC*, filter id\n", ++i); fprintf(fh,"# %d) maximum indel length\n", ++i); fprintf(fh,"# %d-%d) counts at indel lengths (-max,..,0,..,max)\n", i+1, i+MAX_LEN*2+1); fprintf(fh,"#\n"); fprintf(fh, "CMD\t%s", args->argv[0]); for (i=1; iargc; i++) fprintf(fh, " %s",args->argv[i]); fprintf(fh, "\n"); for (i=0; infilters; i++) { flt_stats_t *flt = &args->filters[i]; fprintf(fh,"DEF\tFLT%d\t%s\n", i, flt->expr); } for (i=0; infilters; i++) { stats_t *stats = &args->filters[i].stats; fprintf(fh,"SN%d", i); fprintf(fh,"\t%u", args->ntrio ? args->ntrio : args->nsmpl); fprintf(fh,"\t%u", stats->nsites); fprintf(fh,"\t%u", stats->npass); fprintf(fh,"\t%u", stats->npass_gt); fprintf(fh,"\t%u", stats->nins); fprintf(fh,"\t%u", stats->ndel); fprintf(fh,"\t%u", stats->nframeshift); fprintf(fh,"\t%u", stats->ninframe); fprintf(fh,"\n"); fprintf(fh,"DVAF%d", i); fprintf(fh,"\t%d", NVAF); for (j=0; jnvaf[j]); fprintf(fh,"\n"); fprintf(fh,"DLEN%d", i); fprintf(fh,"\t%d", MAX_LEN); for (j=0; jnlen[j]); fprintf(fh,"\n"); fprintf(fh,"DFRAC%d", i); fprintf(fh,"\t%d", MAX_LEN); for (j=0; jnfrac[j] ) fprintf(fh,"\t%.2f",stats->dfrac[j]/stats->nfrac[j]); else fprintf(fh,"\t."); fprintf(fh,"\n"); fprintf(fh,"NFRAC%d", i); fprintf(fh,"\t%d", MAX_LEN); for (j=0; jnfrac[j]); fprintf(fh,"\n"); } if ( fclose(fh)!=0 ) error("Close failed: %s\n", (!args->output_fname || !strcmp("-",args->output_fname)) ? "stdout" : args->output_fname); } static inline int parse_genotype(int32_t *arr, int ngt1, int idx, int als[2]) { int32_t *ptr = arr + ngt1 * idx; if ( bcf_gt_is_missing(ptr[0]) ) return -1; als[0] = bcf_gt_allele(ptr[0]); if ( ngt1==1 || ptr[1]==bcf_int32_vector_end ) { ptr[1] = ptr[0]; return -2; } if ( bcf_gt_is_missing(ptr[1]) ) return -1; als[1] = bcf_gt_allele(ptr[1]); return 0; } static inline void update_indel_stats(args_t *args, bcf1_t *rec, stats_t *stats, int ismpl, int *als) { int j; if ( als[0] >= args->nad1 || als[1] >= args->nad1 ) error("Incorrect GT allele at %s:%"PRId64" .. %d/%d\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,als[0],als[1]); int32_t *ad_ptr = args->ad_arr + ismpl*args->nad1; // find the allele with most support uint32_t ntot = 0; for (j=0; jnad1; j++) { if ( ad_ptr[j]==bcf_int32_missing ) continue; if ( ad_ptr[j]==bcf_int32_vector_end ) break; ntot += ad_ptr[j]; } if ( !ntot ) return; // Find the alternate allele fraction, total and relative. Set al0 to be the more frequent indel allele. // The genotypes have been already sanitized in parse_genotype(). int al0 = als[0], al1 = als[1]; if ( !(bcf_get_variant_type(rec,al0) & VCF_INDEL) ) { if ( !(bcf_get_variant_type(rec,al1) & VCF_INDEL) ) error("FIXME: this should not happen .. %s:%"PRId64" .. %d/%d\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,al0,al1); al0 = als[1]; al1 = als[0]; } else if ( (bcf_get_variant_type(rec,al1) & VCF_INDEL) && al0!=al1 ) { // Select the more frequent indel allele. if ( ad_ptr[al0] < ad_ptr[al1] ) al0 = als[1], al1 = als[0]; // Record length of both indel alleles int bin = len2bin(rec->d.var[al1].n); if ( bin >= 0 ) stats->nlen[bin]++; } float vaf = (float)ad_ptr[al0] / ntot; int bin = vaf2bin(vaf); stats->nvaf[bin]++; // al0 is now the major indel allele int len_bin = len2bin(rec->d.var[al0].n); if ( len_bin < 0 ) return; stats->nlen[len_bin]++; if ( al0!=al1 ) { ntot = ad_ptr[al0] + ad_ptr[al1]; if ( ntot ) { stats->nfrac[len_bin]++; stats->dfrac[len_bin]+= (double)ad_ptr[al0] / ntot; } } } static void process_record(args_t *args, bcf1_t *rec, flt_stats_t *flt) { int i,j; uint8_t *smpl_pass = NULL; stats_t *stats = &flt->stats; stats->nsites++; // Find out which samples/trios pass and if the site passes if ( flt->filter ) { int pass_site = filter_test(flt->filter, rec, (const uint8_t**) &smpl_pass); if ( args->ntrio ) { if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return; pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( smpl_pass[idx] ) { pass_trio = 0; break; } } args->trio[i].pass = pass_trio; if ( pass_trio ) pass_site = 1; } if ( !pass_site ) return; } else for (i=0; intrio; i++) args->trio[i].pass = 1; } else if ( !pass_site ) return; else if ( smpl_pass ) { pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( !smpl_pass[idx] ) { pass_trio = 0; break; } } args->trio[i].pass = pass_trio; if ( pass_trio ) pass_site = 1; } if ( !pass_site ) return; } else for (i=0; intrio; i++) args->trio[i].pass = 1; } else { if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return; pass_site = 0; for (i=0; insmpl; i++) { if ( smpl_pass[i] ) smpl_pass[i] = 0; else { smpl_pass[i] = 1; pass_site = 1; } } if ( !pass_site ) return; } else for (i=0; insmpl; i++) smpl_pass[i] = 1; } else if ( !pass_site ) return; } } args->ngt = 0; if ( args->nsmpl ) { // Get the genotypes args->ngt = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); args->ngt1 = args->ngt / rec->n_sample; if ( args->ngt>0 ) { // Get the AD counts args->nad = bcf_get_format_int32(args->hdr, rec, "AD", &args->ad_arr, &args->mad_arr); args->nad1 = args->nad / rec->n_sample; if ( args->nad>0 && args->nad1 != rec->n_allele ) error("Incorrect number of FORMAT/AD values at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); } } // Is there a star allele? Don't count overlapping deletions twice int star_allele = -1; for (i=1; in_allele; i++) if ( !rec->d.allele[i][1] && rec->d.allele[i][0]=='*' ) { star_allele = i; break; } if ( args->ngt>0 && args->ntrio ) { int is_dnm = 0; for (i=0; intrio; i++) { if ( flt->filter && !args->trio[i].pass ) continue; // Determine the alternate allele and the genotypes, skip if any of the alleles is missing. // the order is: child, father, mother int als[6], *als_child = als, *als_father = als+2, *als_mother = als+4; if ( parse_genotype(args->gt_arr, args->ngt1, args->trio[i].idx[iCHILD], als_child) < 0 ) continue; if ( parse_genotype(args->gt_arr, args->ngt1, args->trio[i].idx[iFATHER], als_father) < 0 ) continue; if ( parse_genotype(args->gt_arr, args->ngt1, args->trio[i].idx[iMOTHER], als_mother) < 0 ) continue; // Is it a DNM? if ( !args->allow_alt2ref_DNMs && als_child[0]==0 && als_child[1]==0 ) continue; if ( (als_child[0]==als_father[0] || als_child[0]==als_father[1]) && (als_child[1]==als_mother[0] || als_child[1]==als_mother[1]) ) continue; if ( (als_child[1]==als_father[0] || als_child[1]==als_father[1]) && (als_child[0]==als_mother[0] || als_child[0]==als_mother[1]) ) continue; if ( als_child[0]==star_allele || als_child[1]==star_allele ) continue; // don't count the same event multiple times if ( als_father[0]==star_allele || als_father[1]==star_allele ) continue; if ( als_mother[0]==star_allele || als_mother[1]==star_allele ) continue; int child_is_indel = (bcf_get_variant_type(rec,als_child[0]) & VCF_INDEL) || (bcf_get_variant_type(rec,als_child[1]) & VCF_INDEL) ? 1 : 0; if ( !args->allow_alt2ref_DNMs ) { if ( !child_is_indel ) continue; } else { if ( !child_is_indel && !(bcf_get_variant_type(rec,als_father[0]) & VCF_INDEL) && !(bcf_get_variant_type(rec,als_father[1]) & VCF_INDEL) && !(bcf_get_variant_type(rec,als_mother[0]) & VCF_INDEL) && !(bcf_get_variant_type(rec,als_mother[1]) & VCF_INDEL) ) continue; // not an indel, in any sample } if ( child_is_indel ) update_indel_stats(args, rec, stats, args->trio[i].idx[iCHILD], als_child); //printf("MERR\t%s\t%d\t%s\n", bcf_seqname(args->hdr,rec),rec->pos+1,args->hdr->samples[args->trio[i].idx[iCHILD]]); stats->npass_gt++; is_dnm = 1; } if ( !is_dnm ) return; } else if ( args->ngt>0 ) { for (i=0; insmpl; i++) { if ( smpl_pass && !smpl_pass[i] ) continue; // Determine the alternate allele and the genotypes, skip if any of the alleles is missing. int als[2] = {0,0}; int ret = parse_genotype(args->gt_arr, args->ngt1, i, als); if ( ret==-1 ) continue; // missing genotype if ( !(bcf_get_variant_type(rec,als[0]) & VCF_INDEL) && !(bcf_get_variant_type(rec,als[1]) & VCF_INDEL) ) continue; // not an indel update_indel_stats(args, rec, stats, i, als); stats->npass_gt++; } } if ( bcf_get_info_string(args->hdr,rec,args->csq_tag,&args->csq_str,&args->mcsq_str) > 0 ) { if ( strstr(args->csq_str,"inframe") ) stats->ninframe++; if ( strstr(args->csq_str,"frameshift") ) stats->nframeshift++; } for (i=1; in_allele; i++) { if ( !(bcf_get_variant_type(rec,i) & VCF_INDEL) ) continue; if ( rec->d.var[i].n < 0 ) stats->ndel++; else if ( rec->d.var[i].n > 0 ) stats->nins++; if ( args->ngt <= 0 ) { int bin = len2bin(rec->d.var[i].n); if ( bin >= 0 ) stats->nlen[bin]++; } } stats->npass++; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->csq_tag = "CSQ"; static struct option loptions[] = { {"max-len",required_argument,0,1}, {"nvaf",required_argument,0,2}, {"alt2ref-DNM",no_argument,0,3}, {"ped",required_argument,0,'p'}, {"csq-tag",required_argument,0,'c'}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"output",required_argument,NULL,'o'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {NULL,0,NULL,0} }; char *tmp; int c, i; while ((c = getopt_long(argc, argv, "o:s:i:e:r:R:t:T:c:p:",loptions,NULL)) >= 0) { switch (c) { case 1 : MAX_LEN = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --max-len %s\n", optarg); if ( MAX_LEN<=0 ) error("Expected value bigger than 0 --max-len\n"); break; case 2 : NVAF = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --max-len %s\n", optarg); if ( NVAF<0 || NVAF>1 ) error("Expected value from the interval [0,1] with --nvaf\n"); break; case 3 : args->allow_alt2ref_DNMs = 1; break; case 'p': args->ped_fname = optarg; break; case 'c': args->csq_tag = optarg; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else args->fname = argv[optind]; init_data(args); while ( bcf_sr_next_line(args->sr) ) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( !(bcf_get_variant_types(rec) & VCF_INDEL) ) continue; for (i=0; infilters; i++) process_record(args, rec, &args->filters[i]); } report_stats(args); destroy_data(args); return 0; } bcftools-1.21/plugins/isecGT.c000066400000000000000000000212221467060157400162640ustar00rootroot00000000000000/* Copyright (C) 2016-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "smpl_ilist.h" typedef struct { int argc, output_type, regions_is_file, targets_is_file, clevel; char **argv, *output_fname, *regions_list, *targets_list; int32_t *arr_a, narr_a, *arr_b, narr_b; bcf_srs_t *sr; bcf_hdr_t *hdr_a, *hdr_b; htsFile *out_fh; char *index_fn; int write_index; } args_t; const char *about(void) { return "Compare two files and set non-identical genotypes to missing.\n"; } static const char *usage_text(void) { return "\n" "About: Compare two files and set non-identical genotypes in the first file to missing.\n" "\n" "Usage: bcftools +isecGT [Plugin Options]\n" "Plugin options:\n" " -o, --output FILE Write output to a file [standard output]\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " -t, --targets REGION Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n"; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->output_fname = "-"; args->output_type = FT_VCF; args->clevel = -1; static struct option loptions[] = { {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "o:O:r:R:t:T:W::",loptions,NULL)) >= 0) { switch (c) { case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; args->targets_is_file = 1; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind+2!=argc ) error("%s",usage_text()); args->sr = bcf_sr_init(); args->sr->require_index = 1; if ( args->regions_list ) { if ( bcf_sr_set_regions(args->sr, args->regions_list, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { if ( bcf_sr_set_targets(args->sr, args->targets_list, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); args->sr->collapse |= COLLAPSE_BOTH; } if ( !bcf_sr_add_reader(args->sr,argv[optind]) ) error("Error opening %s: %s\n", argv[optind],bcf_sr_strerror(args->sr->errnum)); if ( !bcf_sr_add_reader(args->sr,argv[optind+1]) ) error("Error opening %s: %s\n", argv[optind+1],bcf_sr_strerror(args->sr->errnum)); args->hdr_a = bcf_sr_get_header(args->sr,0); args->hdr_b = bcf_sr_get_header(args->sr,1); smpl_ilist_t *smpl = smpl_ilist_map(args->hdr_a, args->hdr_b, SMPL_STRICT); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( bcf_hdr_write(args->out_fh, args->hdr_a)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr_a,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); while ( bcf_sr_next_line(args->sr) ) { if ( !bcf_sr_has_line(args->sr,0) ) continue; if ( !bcf_sr_has_line(args->sr,1) ) { if ( bcf_write(args->out_fh, args->hdr_a, bcf_sr_get_line(args->sr,0))!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); continue; } bcf1_t *line_a = bcf_sr_get_line(args->sr,0); bcf1_t *line_b = bcf_sr_get_line(args->sr,1); int ngt_a = bcf_get_genotypes(args->hdr_a, line_a, &args->arr_a, &args->narr_a); int ngt_b = bcf_get_genotypes(args->hdr_b, line_b, &args->arr_b, &args->narr_b); assert( ngt_a==ngt_b ); // todo ngt_a /= smpl->n; ngt_b /= smpl->n; int i, j, dirty = 0; for (i=0; in; i++) { int32_t *a = args->arr_a + i*ngt_a; int32_t *b = args->arr_b + smpl->idx[i]*ngt_b; for (j=0; jhdr_a, line_a, args->arr_a, ngt_a*smpl->n); if ( bcf_write(args->out_fh, args->hdr_a, line_a)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("Close failed: %s\n",args->output_fname); smpl_ilist_destroy(smpl); bcf_sr_destroy(args->sr); free(args->arr_a); free(args->arr_b); free(args); return 0; } bcftools-1.21/plugins/isecGT.mk000066400000000000000000000003121467060157400164460ustar00rootroot00000000000000plugins/isecGT.so: plugins/isecGT.c version.h version.c smpl_ilist.h $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(ALL_CPPFLAGS) $(EXTRA_CPPFLAGS) $(LDFLAGS) -o $@ smpl_ilist.c version.c $< $(PLUGIN_LIBS) $(LIBS) bcftools-1.21/plugins/mendelian2.c000066400000000000000000001073501467060157400171330ustar00rootroot00000000000000/* The MIT License Copyright (c) 2015-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include // for isatty #include "bcftools.h" #include "regidx.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define MODE_ANNOTATE (1<<0) // -m a #define MODE_COUNT (1<<1) // -m c #define MODE_DELETE (1<<2) // -m d #define MODE_LIST_ERR (1<<3) // -m e #define MODE_DROP_ERR (1<<4) // -m E #define MODE_LIST_GOOD (1<<5) // -m g #define MODE_LIST_MISS (1<<6) // -m m #define MODE_DROP_MISS (1<<7) // -m M #define MODE_LIST_SKIP (1<<8) // -m s #define MODE_DROP_SKIP (1<<9) // -m S #define LIST_MODES (MODE_LIST_ERR|MODE_LIST_GOOD|MODE_LIST_MISS|MODE_LIST_SKIP) #define iMOM 0 #define iDAD 1 #define iKID 2 typedef struct { int nno_gt, // number of rows with no FMT/GT nnot_diploid, // FMT/GT2 not diploid nfail, // number of -i/-e filters failed nmiss, // number of genotypes with a missing allele in the trio ngood, // number of good genotypes (after any -i/-e filters applied) nmerr, // number of mendelian errors ngood_alt, // number of error-free non-ref genotypes nrule; // number of genotypes with no rule to apply } stats_t; typedef struct { int idx[3]; // VCF sample index of mom,dad,kid, in that order stats_t stats; // per trio stats collected over all sites int fail, has_merr; // per site filtering and mendeian error info int sex_id; // implicitly defined by rules (typically 1X=0, 2X=1), see str2sex_id } trio_t; typedef struct { uint8_t ploidy:4, // 0,1,2 sex_id:2, // id given by str2sex_id mapping inherits:2; // one of the M,F,MF,. inheritance modes given as combination of 1<,proband,father,mother,sex(1:male,2:female)\n" " --rules ASSEMBLY[?] Predefined inheritance rules, \"list\" to print available settings, \"list?\" for detailed information\n" " --rules-file FILE Inheritance rules, run with `--rules list?` for examples\n" "\n" "Example:\n" " # Print number of good, erroneous and missing genotypes\n" " bcftools +mendelian2 in.vcf -p 1X:Child,Father,Mother -c\n" "\n"; } typedef struct { const char *alias, *about, *rules; } rules_predef_t; static rules_predef_t rules_predefs[] = { { .alias = "GRCh37", .about = "Human Genome reference assembly GRCh37 / hg19, both chr naming conventions", .rules = " # Unlisted regions inherit from both parents (MF)\n" " 1X X:1-60000 M\n" " 1X X:2699521-154931043 M\n" " 1X Y:1-59373566 F\n" " 2X Y:1-59373566 .\n" " 1X MT:1-16569 M\n" " 2X MT:1-16569 M\n" "\n" " 1X chrX:1-60000 M\n" " 1X chrX:2699521-154931043 M\n" " 1X chrY:1-59373566 F\n" " 2X chrY:1-59373566 .\n" " 1X chrM:1-16569 M\n" " 2X chrM:1-16569 M\n" }, { .alias = "GRCh38", .about = "Human Genome reference assembly GRCh38 / hg38, both chr naming conventions", .rules = " # Unlisted regions inherit from both parents (MF)\n" " 1X X:1-9999 M\n" " 1X X:2781480-155701381 M\n" " 1X Y:1-57227415 F\n" " 2X Y:1-57227415 .\n" " 1X MT:1-16569 M\n" " 2X MT:1-16569 M\n" "\n" " 1X chrX:1-9999 M\n" " 1X chrX:2781480-155701381 M\n" " 1X chrY:1-57227415 F\n" " 2X chrY:1-57227415 .\n" " 1X chrMT:1-16569 M\n" " 2X chrMT:1-16569 M\n" }, { .alias = NULL, .about = NULL, .rules = NULL, } }; static int parse_rules(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { args_t *args = (args_t*)usr; // e.g // 1X Y:1-59373566 F # son // 2X Y:1-59373566 . # daughter if ( line[0]=='#' ) return -1; // skip comment lines // eat any leading spaces char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) return -1; // skip empty lines // sex id, e.g. 1X or 2X char keep, *tmp, *se = ss; while ( *se && !isspace(*se) ) se++; if ( !*se ) error("Could not parse the sex ID in the region line: %s\n", line); keep = *se; *se = 0; int sex_id = 0; if ( khash_str2int_get(args->str2sex_id,ss,&sex_id)!=0 ) { tmp = strdup(ss); if ( khash_str2int_set(args->str2sex_id,tmp,args->nsex_id) < 0 ) error("Could not insert into a hash\n"); sex_id = args->nsex_id++; } *se = keep; while ( *se && isdigit(*se) ) se++; while ( *se && isspace(*se) ) se++; ss = se; // chromosome name, beg, end while ( se[1] && !isspace(se[1]) ) se++; while ( se > ss && isdigit(*se) ) se--; if ( *se!='-' ) error("Could not parse the region: %s\n",line); *end = strtol(se+1, &tmp, 10) - 1; if ( tmp==se+1 ) error("Could not parse the region: %s\n",line); while ( se > ss && *se!=':' ) se--; *beg = strtol(se+1, &tmp, 10) - 1; if ( tmp==se+1 ) error("Could not parse the region: %s\n",line); *chr_beg = ss; *chr_end = se-1; // skip region while ( *ss && !isspace(*ss) ) ss++; while ( *ss && isspace(*ss) ) ss++; rule_t *rule = (rule_t*) payload; rule->sex_id = sex_id; rule->inherits = 0; rule->ploidy = 0; // alleles inherited from mother (M), father (F), both (MF), none (.) while ( *ss && !isspace(*ss) ) { if ( *ss=='M' ) { rule->inherits |= 1<ploidy++; } else if ( *ss=='F' ) { rule->inherits |= 1<ploidy++; } else if ( *ss=='.' ) { rule->inherits = 0; rule->ploidy = 0; } else error("Could not parse the region: %s\n", line); ss++; if ( rule->ploidy > 2 ) error("Todo: not ready for ploidy > 2: %s\n", line); } return 0; } regidx_t *init_rules(args_t *args, char *alias) { const rules_predef_t *rules = rules_predefs; if ( !alias ) alias = "GRCh37"; int detailed = 0, len = strlen(alias); if ( alias[len-1]=='?' ) { detailed = 1; alias[len-1] = 0; } while ( rules->alias && strcasecmp(alias,rules->alias) ) rules++; if ( !rules->alias ) { fprintf(stderr,"\nPRE-DEFINED INHERITANCE RULES\n\n"); fprintf(stderr," * Columns are: SEX_ID CHROM:BEG-END INHERITED_FROM\n"); fprintf(stderr," * Coordinates are 1-based inclusive.\n\n"); rules = rules_predefs; while ( rules->alias ) { fprintf(stderr,"%s\n .. %s\n\n", rules->alias,rules->about); if ( detailed ) fprintf(stderr,"%s\n", rules->rules); rules++; } fprintf(stderr,"Run as --rules (e.g. --rules GRCh37).\n"); fprintf(stderr,"To see the detailed ploidy definition, append a question mark (e.g. --rules GRCh37?).\n"); fprintf(stderr,"\n"); exit(-1); } else if ( detailed ) { fprintf(stderr,"%s", rules->rules); exit(-1); } return regidx_init_string(rules->rules, parse_rules, NULL, sizeof(rule_t), args); } static int cmp_trios(const void *_a, const void *_b) { trio_t *a = (trio_t *) _a; trio_t *b = (trio_t *) _b; int i; int amin = a->idx[0]; for (i=1; i<3; i++) if ( amin > a->idx[i] ) amin = a->idx[i]; int bmin = b->idx[0]; for (i=1; i<3; i++) if ( bmin > b->idx[i] ) bmin = b->idx[i]; if ( amin < bmin ) return -1; if ( amin > bmin ) return 1; return 0; } static void parse_ped(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); kstring_t str = {0,0,0}; if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); int moff = 0, *off = NULL, mtrio = 0; do { // familyID sampleID paternalID maternalID sex phenotype population relationship siblings secondOrder thirdOrder children comment // BB03 HG01884 HG01885 HG01956 2 0 ACB child 0 0 0 0 int ncols = ksplit_core(str.s,0,&moff,&off); if ( ncols<4 ) error("Could not parse the ped file: %s\n", str.s); int dad = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[2]]); if ( dad < 0 ) continue; int mom = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[3]]); if ( mom < 0 ) continue; int kid = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); if ( kid < 0 ) continue; int sex = 0; if ( ncols>=5 ) { char *tmp; sex = strtol(&str.s[off[4]],&tmp,10); if ( tmp==&str.s[off[4]] || *tmp ) error("Could not parse the PED file, the 5th column should be numeric: %s\n",str.s); if ( sex!=1 && sex!=2 ) sex = 0; } args->ntrio++; hts_expand0(trio_t,args->ntrio,mtrio,args->trio); trio_t *trio = &args->trio[args->ntrio-1]; trio->idx[iDAD] = dad; trio->idx[iMOM] = mom; trio->idx[iKID] = kid; if ( khash_str2int_get(args->str2sex_id, sex==1 ? "1X" : "2X", &trio->sex_id)<0 ) error("Missing the sex \"%s\", it's not in the rules :-/\n",sex==1 ? "1X" : "2X"); } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); // sort the sample by index so that they are accessed more or less sequentially qsort(args->trio,args->ntrio,sizeof(trio_t),cmp_trios); // check for duplicates int i; for (i=1; intrio; i++) { trio_t *ta = &args->trio[i-1]; trio_t *tb = &args->trio[i]; if ( ta->idx[0]==tb->idx[0] && ta->idx[1]==tb->idx[1] && ta->idx[2]==tb->idx[2] ) error("Error: duplicate trio entries detected in the PED file: %s\n",fname); } fprintf(stderr,"Identified %d complete trio%s in the VCF file\n", args->ntrio,args->ntrio==1?"":"s"); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; bcf_sr_set_opt(args->sr,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets ) { bcf_sr_set_opt(args->sr,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); } if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); args->str2sex_id = khash_str2int_init(); if ( args->rules_fname ) args->rules = regidx_init(args->rules_fname, parse_rules, NULL, sizeof(rule_t), args); else args->rules = init_rules(args, args->rules_str); if ( !args->rules ) error("Could not parse the Mendelian rules\n"); args->itr = regitr_init(args->rules); args->rule = (rule_t*) malloc(sizeof(*args->rule)*args->nsex_id); int i, n = 0; char **list; if ( args->pfm ) { args->ntrio = 1; args->trio = (trio_t*) calloc(1,sizeof(trio_t)); list = hts_readlist(args->pfm, 0, &n); if ( n!=3 ) error("Expected three sample names with -t\n"); const int ped_idx[3] = {2,1,0}; // sample order is different on the command line (P,F,M) and in the code (M,F,P) for (i=0; i<3; i++) args->trio[0].idx[i] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[ped_idx[i]]); if ( args->trio[0].idx[iKID] < 0 ) { if ( strlen(list[0])>3 && !strncasecmp(list[0],"1X:",3) ) { args->trio[0].idx[iKID] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[0]+3); args->trio[0].sex_id = iDAD; } else if ( strlen(list[0])>3 && !strncasecmp(list[0],"2X:",3) ) { args->trio[0].idx[iKID] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[0]+3); args->trio[0].sex_id = iMOM; } } for (i=0; i<3; i++) { if ( args->trio[0].idx[i] < 0 ) error("The sample is not present: %s\n", list[ped_idx[i]]); free(list[ped_idx[i]]); } free(list); } else { parse_ped(args,args->ped_fname); if ( !args->ntrio ) error("No complete trio present\n"); } args->hdr_out = bcf_hdr_dup(args->hdr); if ( args->mode&MODE_ANNOTATE ) bcf_hdr_append(args->hdr_out,"##INFO="); if ( args->record_cmd_line ) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_trio-dnm2"); if ( args->mode!=MODE_COUNT ) { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( bcf_hdr_write(args->out_fh, args->hdr_out)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr_out,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); } } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); regidx_destroy(args->rules); regitr_destroy(args->itr); khash_str2int_destroy_free(args->str2sex_id); free(args->trio); free(args->gt_arr); free(args->rule); if ( args->out_fh ) { if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); } bcf_hdr_destroy(args->hdr_out); bcf_sr_destroy(args->sr); free(args); } static int test_filters(args_t *args, bcf1_t *rec) { uint8_t *smpl_pass; int i,j, pass_site = filter_test(args->filter, rec, (const uint8_t**) &smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return 0; // no samples, -e mode, the expression failed pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( smpl_pass[idx] ) { pass_trio = 0; break; } // with -e one sample passes, the whole trio fails } args->trio[i].fail = pass_trio ? 0 : 1; if ( pass_trio ) pass_site = 1; } return pass_site; } for (i=0; intrio; i++) args->trio[i].fail = 0; return 1; } if ( !pass_site ) return 0; if ( smpl_pass ) { pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( !smpl_pass[idx] ) { pass_trio = 0; break; } } args->trio[i].fail = pass_trio ? 0 : 1; if ( pass_trio ) pass_site = 1; } return pass_site; } for (i=0; intrio; i++) args->trio[i].fail = 0; return 1; } static int parse_gt(int32_t *gt, int ngt, uint64_t *a, uint64_t *b) { *a = *b = 0; if ( gt[0]==bcf_gt_missing || gt[0]==bcf_int32_vector_end ) return 0; *a |= 1<nmerr = 0; int ret = 0; int ngt = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->ngt_arr); if ( ngt<0 ) { args->stats.nno_gt++; return ret; } if ( ngt!=2*bcf_hdr_nsamples(args->hdr) && ngt!=bcf_hdr_nsamples(args->hdr) ) { args->stats.nnot_diploid++; return ret; } ngt /= bcf_hdr_nsamples(args->hdr); int i,j,itr_set = regidx_overlap(args->rules, bcf_seqname(args->hdr,rec),rec->pos,rec->pos+rec->rlen-1, args->itr); for (i=0; insex_id; i++) { args->rule[i].sex_id = i; args->rule[i].inherits = (1<rule[i].ploidy = 2; } while ( itr_set && regitr_overlap(args->itr) ) { rule_t *rule = ®itr_payload(args->itr,rule_t); args->rule[rule->sex_id] = *rule; } for (i=0; intrio; i++) { trio_t *trio = &args->trio[i]; trio->has_merr = 0; if ( trio->fail ) { trio->stats.nfail++; continue; } rule_t *rule = &args->rule[trio->sex_id]; if ( !rule->inherits ) { trio->stats.nrule++; continue; } uint64_t kid1, kid2, parent, mom, dad; int nal = parse_gt(&args->gt_arr[ngt*trio->idx[iKID]],ngt,&kid1,&kid2); if ( nal < rule->ploidy ) { ret |= HAS_MISS; trio->stats.nmiss++; continue; } if ( nal==1 ) { for (j=0; jnsex_id; j++) { if ( rule->inherits & (1<gt_arr[ngt*trio->idx[j]],ngt,&parent,&parent); if ( !nal ) { ret |= HAS_MISS; trio->stats.nmiss++; continue; } if ( parent&kid1 ) { ret |= HAS_GOOD; trio->stats.ngood++; if ( parent!=1 || parent!=kid1 ) trio->stats.ngood_alt++; continue; } ret |= HAS_MERR; trio->stats.nmerr++; trio->has_merr = 1; args->nmerr++; continue; } int nal_mom = parse_gt(&args->gt_arr[ngt*trio->idx[iMOM]],ngt,&mom,&mom); int nal_dad = parse_gt(&args->gt_arr[ngt*trio->idx[iDAD]],ngt,&dad,&dad); if ( (kid1&dad && kid2&mom) || (kid1&mom && kid2&dad) ) { // both children's alleles phased ret |= HAS_GOOD; trio->stats.ngood++; if ( dad!=1 || mom!=1 || (kid1|kid2)!=1 ) trio->stats.ngood_alt++; continue; } if ( !nal_mom || !nal_dad ) { ret |= HAS_MISS; trio->stats.nmiss++; } // one or both parents missing if ( !nal_mom && !nal_dad ) continue; // both parents missing if ( !nal_mom && ((kid1|kid2)&dad) ) continue; // one parent missing but the kid is consistent with the other if ( !nal_dad && ((kid1|kid2)&mom) ) continue; ret |= HAS_MERR; trio->stats.nmerr++; trio->has_merr = 1; args->nmerr++; } if ( !(args->mode&MODE_DELETE) || !(ret&HAS_MERR) ) return ret; for (i=0; intrio; i++) { trio_t *trio = &args->trio[i]; if ( !trio->has_merr ) continue; delete_gt(&args->gt_arr[ngt*trio->idx[iKID]],ngt); delete_gt(&args->gt_arr[ngt*trio->idx[iDAD]],ngt); delete_gt(&args->gt_arr[ngt*trio->idx[iMOM]],ngt); } bcf_update_genotypes(args->hdr_out, rec, args->gt_arr, ngt*bcf_hdr_nsamples(args->hdr)); return ret; } static int process_record(args_t *args, bcf1_t *rec) // returns 1 to print rec, 0 to suppress printing { int skip_site = 0; if ( rec->n_allele==1 || bcf_get_variant_types(rec)==VCF_REF ) { args->nref_only++; skip_site = 1; } else if ( rec->n_allele > 64 ) // we use uint64_t bitmask in collect_stats() { args->nmany_als++; skip_site = 1; } else if ( args->filter && !test_filters(args,rec) ) { args->stats.nfail++; skip_site = 1; } if ( skip_site ) return args->mode&MODE_DROP_SKIP ? 1 : 0; int ret = collect_stats(args, rec); if ( ret&HAS_MERR ) args->stats.nmerr++; if ( ret&HAS_MISS ) args->stats.nmiss++; if ( ret&HAS_GOOD ) args->stats.ngood++; if ( args->mode&MODE_COUNT ) return 0; if ( args->mode&MODE_DROP_ERR && ret&HAS_MERR ) return 0; if ( args->mode&MODE_DROP_MISS && ret&HAS_MISS ) return 0; if ( args->mode&MODE_ANNOTATE ) { bcf_update_info_int32(args->hdr_out,rec,"MERR",&args->nmerr,1); } if ( args->mode&LIST_MODES ) { if ( args->mode&MODE_LIST_ERR && ret&HAS_MERR ) return 1; if ( args->mode&MODE_LIST_MISS && ret&HAS_MISS ) return 1; if ( args->mode&MODE_LIST_GOOD && ret&HAS_GOOD ) return 1; return 0; } return 1; } static void print_stats(args_t *args) { if ( !(args->mode & MODE_COUNT) ) return; FILE *log_fh = stderr; if ( args->mode==MODE_COUNT ) { log_fh = strcmp("-",args->output_fname) ? fopen(args->output_fname,"w") : stdout; if ( !log_fh ) error("Error: cannot write to %s\n", args->output_fname); } fprintf(log_fh,"# Summary stats\n"); fprintf(log_fh,"sites_ref_only\t%d\t# sites skipped because there was no ALT allele\n", args->nref_only); fprintf(log_fh,"sites_many_als\t%d\t# skipped because of too many ALT alleles\n", args->nmany_als); fprintf(log_fh,"sites_fail\t%d\t# skipped because of failed -i/-e filter\n", args->stats.nfail); fprintf(log_fh,"sites_no_GT\t%d\t# skipped because of absent FORMAT/GT field\n", args->stats.nno_gt); fprintf(log_fh,"sites_not_diploid\t%d\t# skipped because FORMAT/GT not formatted diploid\n", args->stats.nnot_diploid); fprintf(log_fh,"sites_missing\t%d\t# number of sites with at least one trio GT missing\n", args->stats.nmiss); fprintf(log_fh,"sites_merr\t%d\t# number of sites with at least one Mendelian error\n", args->stats.nmerr); fprintf(log_fh,"sites_good\t%d\t# number of sites with at least one good trio\n", args->stats.ngood); int i; fprintf(log_fh,"# Per-trio stats, each column corresponds to one trio. List of trios is below.\n"); fprintf(log_fh,"# The meaning of per-trio stats is the same as described above, ngood_alt is\n"); fprintf(log_fh,"# the number of good genotypes with at least one non-reference allele, and is\n"); fprintf(log_fh,"# included in the ngood counter\n"); fprintf(log_fh,"ngood"); for (i=0; intrio; i++) fprintf(log_fh,"\t%d",args->trio[i].stats.ngood); fprintf(log_fh,"\n"); fprintf(log_fh,"ngood_alt"); for (i=0; intrio; i++) fprintf(log_fh,"\t%d",args->trio[i].stats.ngood_alt); fprintf(log_fh,"\n"); fprintf(log_fh,"nmerr"); for (i=0; intrio; i++) fprintf(log_fh,"\t%d",args->trio[i].stats.nmerr); fprintf(log_fh,"\n"); fprintf(log_fh,"nmissing"); for (i=0; intrio; i++) fprintf(log_fh,"\t%d",args->trio[i].stats.nmiss); fprintf(log_fh,"\n"); fprintf(log_fh,"nfail"); for (i=0; intrio; i++) fprintf(log_fh,"\t%d",args->trio[i].stats.nfail); fprintf(log_fh,"\n"); fprintf(log_fh,"# List of trios. Their ids are in the same order as the values listed in the stats lines above. For\n"); fprintf(log_fh,"# example, the values for the first trio (id=1) and the third trio (id=3) are in the 2nd and the 4th\n"); fprintf(log_fh,"# column and their stats can be obtained with the unix command\n"); fprintf(log_fh,"# cat stats.txt | grep ^n | cut -f1,2,4\n"); fprintf(log_fh,"# TRIO\t[2]id\t[3]child\t[4]father\t[5]mother\n"); for (i=0; intrio; i++) { trio_t *trio = &args->trio[i]; fprintf(log_fh,"TRIO\t%d\t%s\t%s\t%s\n", i+1, bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,trio->idx[iKID]), bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,trio->idx[iDAD]), bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,trio->idx[iMOM])); } if ( log_fh!=stderr && log_fh!=stdout && fclose(log_fh) ) error("Error: close failed for %s\n", args->output_fname); } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->record_cmd_line = 1; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"pfm",1,0,'p'}, {"ped",1,0,'P'}, {"mode",1,0,'m'}, {"rules",1,0,1}, {"rules-file",1,0,2}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,14}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,15}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"write-index",optional_argument,NULL,'W'}, {0,0,0,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "?hp:P:m:o:O:i:e:t:T:r:R:W::",loptions,NULL)) >= 0) { switch (c) { case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'm': tmp = optarg; while ( *tmp ) { if ( *tmp=='+' || *tmp=='g' ) args->mode |= MODE_LIST_GOOD; else if ( *tmp=='x' || *tmp=='e' ) args->mode |= MODE_LIST_ERR; else if ( *tmp=='a' ) args->mode |= MODE_ANNOTATE; else if ( *tmp=='d' ) args->mode |= MODE_DELETE; else if ( *tmp=='c' ) args->mode |= MODE_COUNT; else if ( *tmp=='E' ) args->mode |= MODE_DROP_ERR; else if ( *tmp=='u' || *tmp=='m' ) args->mode |= MODE_LIST_MISS; else if ( *tmp=='M' ) args->mode |= MODE_DROP_MISS; else if ( *tmp=='s' ) args->mode |= MODE_LIST_SKIP; else if ( *tmp=='S' ) args->mode |= MODE_DROP_SKIP; else error("The argument \"%c\" not recognised: --mode %s\n", *tmp,optarg); tmp++; } break; case 'P': args->ped_fname = optarg; break; case 'p': args->pfm = optarg; break; case 1 : args->rules_str = optarg; break; case 2 : args->rules_fname = optarg; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s",usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->ped_fname && !args->pfm ) error("Missing the -p or -P option\n"); if ( args->ped_fname && args->pfm ) error("Expected only -p or -P option, not both\n"); if ( !args->mode ) args->mode = MODE_COUNT; init_data(args); while ( bcf_sr_next_line(args->sr) ) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( !process_record(args, rec) ) continue; if ( bcf_write(args->out_fh, args->hdr_out, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } print_stats(args); destroy_data(args); return 0; } bcftools-1.21/plugins/missing2ref.c000066400000000000000000000101061467060157400173350ustar00rootroot00000000000000/* plugins/missing2ref.c -- sets missing genotypes to reference allele. Copyright (C) 2014-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include bcf_hdr_t *in_hdr, *out_hdr; int32_t *gts = NULL, mgts = 0; int *arr = NULL, marr = 0; uint64_t nchanged = 0; int new_gt = bcf_gt_unphased(0); int use_major = 0; const char *about(void) { return "Set missing genotypes (\"./.\") to ref or major allele (\"0/0\" or \"0|0\").\n"; } const char *usage(void) { return "\n" "About: Set missing genotypes\n" "Usage: bcftools +missing2ref [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -p, --phased Set to \"0|0\" \n" " -m, --major Set to major allele \n" "\n" "Example:\n" " bcftools +missing2ref in.vcf -- -p\n" " bcftools +missing2ref in.vcf -- -p -m\n" "\n"; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { int c; static struct option loptions[] = { {"phased",0,0,'p'}, {"major",0,0,'m'}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "mp?h",loptions,NULL)) >= 0) { switch (c) { case 'p': new_gt = bcf_gt_phased(0); break; case 'm': use_major = 1; break; case 'h': case '?': default: fprintf(stderr,"%s", usage()); exit(1); break; } } in_hdr = in; out_hdr = out; return 0; } bcf1_t *process(bcf1_t *rec) { int ngts = bcf_get_genotypes(in_hdr, rec, >s, &mgts); int i, changed = 0; // Calculating allele frequency for each allele and determining major allele // only do this if use_major is true int majorAllele = -1; int maxAC = -1; if(use_major == 1){ hts_expand(int,rec->n_allele,marr,arr); int ret = bcf_calc_ac(in_hdr,rec,arr,BCF_UN_FMT); if(ret > 0){ for(i=0; i < rec->n_allele; ++i){ if(*(arr+i) > maxAC){ maxAC = *(arr+i); majorAllele = i; } } } else{ fprintf(stderr,"Warning: Could not calculate allele count at position %"PRId64"\n", (int64_t) rec->pos); exit(1); } // replacing new_gt by major allele if(bcf_gt_is_phased(new_gt)) new_gt = bcf_gt_phased(majorAllele); else new_gt = bcf_gt_unphased(majorAllele); } // replace gts for (i=0; i Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include // for isatty #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define CNV_DEL 0 #define CNV_DUP 1 #define iCHILD 0 #define iFATHER 1 #define iMOTHER 2 typedef struct { int idx[3]; // VCF sample index for child, father, mother int pass; // do all three pass the filters? } trio_t; typedef struct { int argc, filter_logic, cnv_type, debug, greedy; filter_t *filter; char *filter_str; char **argv, *pfm, *fname, *region; bcf_srs_t *sr; bcf_hdr_t *hdr; trio_t trio; int32_t *pl, *ad, *gt; // input FMT/PL, AD, and GT values int mpl, mad, mgt; double ppat,pmat; // method 1: probability of paternal/maternal origin int ntest; // number of informative sites int nmat, npat; // method 2: number of pat/mat sites based on simple ad[0] < ad[1] comparison double min_pbinom; // minimum binomial probability of paternal hets } args_t; args_t args; const char *about(void) { return "Determine parental origin of a CNV region in a trio.\n"; } static const char *usage_text(void) { return "\n" "About: Determine parental origin of a CNV region\n" "Usage: bcftools +parental-origin [Plugin Options]\n" "Plugin options:\n" " -b, --min-binom-prob FLOAT exclude parental HETs with skewed ALT allele fraction [1e-2]\n" " -d, --debug list informative sites\n" " -e, --exclude EXPR exclude sites and samples for which the expression is true\n" " -g, --greedy use also ambiguous sites, e.g. het+hom parents for deletions\n" " -i, --include EXPR include sites and samples for which the expression is true\n" " -p, --pfm P,F,M sample names of proband, father, and mother\n" " -r, --region REGION chr:beg-end\n" " -t, --type the CNV type\n" "\n" "Example:\n" " bcftools +parental-origin -p proband,father,mother -t dup -r 14:22671179-22947951 file.bcf\n" "\n"; } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->region ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->region, 0)<0 ) error("Failed to read the region: %s\n",args->region); } if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); int id; if ( (id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) error("Error: the tag FORMAT/PL is not present in %s\n", args->fname); if ( (id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "AD"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) error("Error: the tag FORMAT/AD is not present in %s\n", args->fname); if ( (id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) error("Error: the tag FORMAT/GT is not present in %s\n", args->fname); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); int i, n = 0; char **list; list = hts_readlist(args->pfm, 0, &n); if ( n!=3 ) error("Expected three sample names with -t\n"); args->trio.idx[iCHILD] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[0]); args->trio.idx[iFATHER] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[1]); args->trio.idx[iMOTHER] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[2]); for (i=0; itrio.idx[i] < 0 ) error("The sample is not present: %s\n", list[i]); free(list[i]); } free(list); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); free(args->pl); free(args->ad); free(args->gt); bcf_sr_destroy(args->sr); free(args); } static void process_record(args_t *args, bcf1_t *rec) { if ( rec->n_allele!=2 || bcf_get_variant_types(rec)!=VCF_SNP ) return; int i,j; if ( args->filter ) { uint8_t *smpl_pass = NULL; int pass_site = filter_test(args->filter, rec, (const uint8_t**) &smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return; pass_site = 0; for (i=0; i<3; i++) { if ( smpl_pass[args->trio.idx[i]] ) smpl_pass[args->trio.idx[i]] = 0; else { smpl_pass[args->trio.idx[i]] = 1; pass_site = 1; } } if ( !pass_site ) return; } else for (i=0; i<3; i++) smpl_pass[args->trio.idx[i]] = 1; } else if ( !pass_site ) return; if ( smpl_pass ) { for (i=0; i<3; i++) if ( !smpl_pass[args->trio.idx[i]] ) return; } } int nsmpl = bcf_hdr_nsamples(args->hdr); int nret = bcf_get_format_int32(args->hdr,rec,"AD",&args->ad,&args->mad); if ( nret<=0 ) { printf("The FORMAT/AD tag not present at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); return; } int nad1 = nret/nsmpl; nret = bcf_get_format_int32(args->hdr,rec,"PL",&args->pl,&args->mpl); if ( nret<=0 ) error("The FORMAT/PL tag not present at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); int npl1 = nret/nsmpl; if ( npl1!=rec->n_allele*(rec->n_allele+1)/2 ) { printf("todo: not a diploid site at %s:%"PRId64": %d alleles, %d PLs\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,rec->n_allele,npl1); return; } nret = bcf_get_genotypes(args->hdr,rec,&args->gt,&args->mgt); if ( nret<=0 ) error("The FORMAT/GT tag not present at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); int ngt1 = nret/nsmpl; if ( ngt1!=2 ) error("Todo: assuming diploid fields for now .. %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); // number of ref and alt alleles in the proband int32_t ad[6], *adP = ad, *adF = ad+2, *adM = ad+4; int32_t dsg[3], *dsgP = dsg, *dsgF = dsg+1, *dsgM = dsg+2; double gl[9], *glP = gl, *glF = gl+3, *glM = gl+6; for (i=0; i<3; i++) // trio { int isum = 0; int32_t *src = args->pl + npl1*args->trio.idx[i]; double *gl_dst = gl + 3*i; double sum = 0; for (j=0; j<3; j++) // iterate over PL { if ( src[j]==bcf_int32_missing || src[j]==bcf_int32_vector_end ) return; gl_dst[j] = pow(10,-0.1*src[j]); sum += gl_dst[j]; isum += src[j]; } if ( isum==0 ) return; for (j=0; j<3; j++) gl_dst[j] /= sum; int32_t *gt = args->gt + ngt1*args->trio.idx[i]; dsg[i] = 0; for (j=0; jad + nad1*args->trio.idx[i]; ad[2*i] = src[0]; ad[2*i+1] = src[1]; } #define is_RR(x) (x[0]==0) #define is_RA(x) (x[1]==0) #define is_AA(x) (x[2]==0) if ( args->cnv_type==CNV_DEL ) { if ( *dsgP!=0 && *dsgP!=2 ) return; // proband not a hom if ( *dsgF == *dsgM ) return; // cannot distinguish between parents if ( !args->greedy ) { if ( *dsgF==1 && *dsgP==*dsgM ) return; // both parents have the proband's allele if ( *dsgM==1 && *dsgP==*dsgF ) return; } double pmat = glP[0]*(0.5*glM[0]*glF[0] + 2/3.*glM[0]*glF[1] + glM[0]*glF[2] + 1/3.*glM[1]*glF[0] + 0.5*glM[1]*glF[1] + glM[1]*glF[2]) + glP[2]*(0.5*glM[2]*glF[2] + 2/3.*glM[2]*glF[1] + glM[2]*glF[0] + 1/3.*glM[1]*glF[2] + 0.5*glM[1]*glF[1] + glM[1]*glF[0]); double ppat = glP[0]*(0.5*glM[0]*glF[0] + 2/3.*glM[1]*glF[0] + glM[2]*glF[0] + 1/3.*glM[0]*glF[1] + 0.5*glM[1]*glF[1] + glM[2]*glF[1]) + glP[2]*(0.5*glM[2]*glF[2] + 2/3.*glM[1]*glF[2] + glM[0]*glF[2] + 1/3.*glM[2]*glF[1] + 0.5*glM[1]*glF[1] + glM[0]*glF[1]); // NB: pmat/ppat is the probability of parental origin of the observed, not the deleted allele; // args->pmat/ppat is the probability of parental origin of the deleted allele args->pmat += log(ppat); args->ppat += log(pmat); args->ntest++; if ( args->debug ) { // output: position, paternal probability, maternal probability, PLs of child, father, mother printf("DBG\t%"PRId64"\t%e\t%e\t", (int64_t) rec->pos+1,ppat,pmat); for (i=0; i<3; i++) { for (j=0; j<3; j++) printf(" %d",args->pl[npl1*args->trio.idx[i]+j]); printf("\t"); } printf("\n"); } } if ( args->cnv_type==CNV_DUP ) { if ( !adP[0] || !adP[1] ) return; // proband is homozygous or has no coverage if ( adP[0] == adP[1] ) return; // proband's alleles are not informative, any or none could have been duplicated if ( *dsgP!=1 ) return; // the proband's genotype is not a het if ( *dsgF == *dsgM ) return; // cannot distinguish between parents if ( args->min_pbinom!=0 ) { // exclude parental hets with skewed ALT allele proportion if ( *dsgF==1 && adF[0] && adF[1] && calc_binom_two_sided(adF[0],adF[1],0.5) < args->min_pbinom ) return; if ( *dsgM==1 && adM[0] && adM[1] && calc_binom_two_sided(adM[0],adM[1],0.5) < args->min_pbinom ) return; } double prra = glP[1] * calc_binom_one_sided(adP[1],adP[0],1/3.,1); double praa = glP[1] * calc_binom_one_sided(adP[1],adP[0],2/3.,0); double ppat = prra*(glM[1]*glF[0] + glM[2]*glF[0] + 0.5*glM[1]*glF[1] + glM[2]*glF[1]) + praa*(glM[1]*glF[2] + glM[0]*glF[2] + 0.5*glM[1]*glF[1] + glM[0]*glF[1]); double pmat = prra*(glM[0]*glF[1] + glM[0]*glF[2] + 0.5*glM[1]*glF[1] + glM[1]*glF[2]) + praa*(glM[2]*glF[1] + glM[2]*glF[0] + 0.5*glM[1]*glF[1] + glM[1]*glF[0]); args->pmat += log(pmat); args->ppat += log(ppat); args->ntest++; if ( args->debug ) { // output: position; paternal probability; maternal probability; ADs of child, father,mother; PLs of child, father, mother printf("DBG\t%"PRId64"\t%e\t%e\t", (int64_t) rec->pos+1,ppat,pmat); for (i=0; i<3; i++) { printf("%d %d\t",ad[2*i],ad[2*i+1]); } for (i=0; i<3; i++) { for (j=0; j<3; j++) printf(" %d",args->pl[npl1*args->trio.idx[i]+j]); printf("\t"); } printf("\n"); } } } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->min_pbinom = 1e-2; static struct option loptions[] = { {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"pfm",required_argument,NULL,'p'}, {"region",required_argument,0,'r'}, {"type",required_argument,0,'t'}, {"debug",no_argument,0,'d'}, {"greedy",no_argument,0,'g'}, {"min-binom-prob",required_argument,0,'b'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "h?e:i:p:r:t:dgb:",loptions,NULL)) >= 0) { switch (c) { case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': if ( !strcasecmp("dup",optarg) ) args->cnv_type = CNV_DUP; else if ( !strcasecmp("del",optarg) ) args->cnv_type = CNV_DEL; break; case 'r': args->region = optarg; break; case 'p': args->pfm = optarg; break; case 'd': args->debug = 1; break; case 'g': args->greedy = 1; break; case 'b': args->min_pbinom = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -b %s\n", optarg); if ( args->min_pbinom<0 || args->min_pbinom>1 ) error("Expected value from the interval [0,1] with --min-binom-prob\n"); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->pfm ) error("Missing the -p option\n"); init_data(args); if ( args->debug ) { if ( args->cnv_type==CNV_DEL ) printf("# DBG: position; paternal probability; maternal probability; PLs of child, father, mother\n"); else printf("# DBG: position; paternal probability; maternal probability; ADs of child, father, mother; PLs of child, father, mother\n"); } while ( bcf_sr_next_line(args->sr) ) process_record(args, bcf_sr_get_line(args->sr,0)); double qual = 4.3429*fabs(args->ppat - args->pmat); char *origin = "uncertain"; if ( args->ppat > args->pmat ) origin = "paternal"; else if ( args->ppat < args->pmat ) origin = "maternal"; int i; printf("# bcftools +%s", args->argv[0]); for (i=1; iargc; i++) printf(" %s",args->argv[i]); printf("\n"); printf("# [1]type\t[2]predicted_origin\t[3]quality\t[4]nmarkers\n"); printf("%s\t%s\t%f\t%d\n", args->cnv_type==CNV_DUP ? "dup" : "del", origin, qual, args->ntest); destroy_data(args); return 0; } bcftools-1.21/plugins/prune.c000066400000000000000000000520321467060157400162420ustar00rootroot00000000000000/* Copyright (C) 2017-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Prune sites by missingness, LD See calc_ld() in vcfbuf.c for the actual LD calculation */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "vcfbuf.h" #include "filter.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define LD_ANNOTATE 1 #define LD_SET_MAX 2 typedef struct { filter_t *filter; char *filter_str, *af_tag; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) vcfbuf_t *vcfbuf; double ld_max[VCFBUF_LD_N]; int ld_max_set[VCFBUF_LD_N]; char *ld_annot[VCFBUF_LD_N], *ld_annot_pos[VCFBUF_LD_N]; int ld_mask; int argc, region_is_file, target_is_file, output_type, ld_filter_id, rand_missing, nsites, ld_win, rseed, clevel; char *nsites_mode; int keep_sites; char **argv, *region, *target, *fname, *output_fname, *ld_filter; htsFile *out_fh; bcf_hdr_t *hdr; bcf_srs_t *sr; char *index_fn; int write_index; } args_t; const char *about(void) { return "Prune sites by missingness, linkage disequilibrium\n"; } static const char *usage_text(void) { return "\n" "About: Prune sites by missingness or linkage disequilibrium.\n" "\n" "Usage: bcftools +prune [Options]\n" "Plugin options:\n" " --AF-tag STR Use this tag with -n to determine allele frequency\n" " -a, --annotate r2,LD Add position of an upstream record with the biggest r2/LD value\n" " -e, --exclude EXPR Exclude sites for which the expression is true\n" " -f, --set-filter STR Apply soft filter STR instead of discarding the site (only with -m)\n" " -i, --include EXPR Include only sites for which the expression is true\n" " -k, --keep-sites Leave sites filtered by -i/-e unchanged instead of discarding them\n" " -m, --max [r2|LD=]FLOAT Remove sites with r2 or Lewontin's D bigger than FLOAT within the -w window\n" " -n, --nsites-per-win N Keep at most N sites in the -w window. See also -N, --nsites-per-win-mode\n" " -N, --nsites-per-win-mode STR Keep sites with biggest AF (\"maxAF\"); sites that come first (\"1st\"); pick randomly (\"rand\") [maxAF]\n" " -o, --output FILE Write output to the FILE [standard output]\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " --random-seed INT Use the provided random seed for reproducibility\n" " --randomize-missing Replace missing data with randomly assigned genotype based on site's allele frequency\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " -t, --targets REGION Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " -w, --window INT[bp|kb|Mb] The window size of INT sites or INT bp/kb/Mb for the -n/-l options [100kb]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "Examples:\n" " # Discard records with r2 bigger than 0.6 in a window of 1000 sites\n" " bcftools +prune -m 0.6 -w 1000 input.bcf -Ob -o output.bcf\n" "\n" " # Set FILTER (but do not discard) records with r2 bigger than 0.4 in the default window of 100kb\n" " bcftools +prune -m 0.4 -f MAX_R2 input.bcf -Ob -o output.bcf\n" "\n" " # Filter nothing, only annotate each site with r2 and LD to the previous site\n" " bcftools +prune -w 1 -a r2,LD -f . input.bcf -Ob -o output.bcf\n" "\n" " # Annotate INFO field of all records with maximum r2 in a window of 1000 sites\n" " bcftools +prune -m 0.6 -w 1000 -f MAX_R2 input.bcf -Ob -o output.bcf\n" "\n" " # Discard records with r2 bigger than 0.6, first removing records with more than 2% of genotypes missing\n" " bcftools +prune -m 0.6 -e'F_MISSING>=0.02' input.bcf -Ob -o output.bcf\n" "\n"; } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->region ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->region, args->region_is_file)<0 ) error("Failed to read the regions: %s\n",args->region); } if ( args->target && bcf_sr_set_targets(args->sr, args->target, args->target_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->target); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->ld_filter && strcmp(".",args->ld_filter) ) { kstring_t str = {0,0,0}; if ( args->ld_max_set[VCFBUF_LD_IDX_R2] ) { kputs("R2 bigger than ",&str); kputd(args->ld_max[VCFBUF_LD_IDX_R2],&str); } if ( args->ld_max_set[VCFBUF_LD_IDX_LD] ) { if ( str.l ) kputs(" or ",&str); kputs("LD bigger than ",&str); kputd(args->ld_max[VCFBUF_LD_IDX_LD],&str); } if ( args->ld_max_set[VCFBUF_LD_IDX_HD] ) { if ( str.l ) kputs(" or ",&str); kputs("HD bigger than ",&str); kputd(args->ld_max[VCFBUF_LD_IDX_HD],&str); } bcf_hdr_printf(args->hdr,"##FILTER=",args->ld_filter, args->ld_win < 0 ? -args->ld_win/1000 : args->ld_win, args->ld_win < 0 ? "kb" : " sites", str.s); free(str.s); } if ( args->ld_mask & LD_ANNOTATE ) { if ( args->ld_annot[VCFBUF_LD_IDX_R2] ) { bcf_hdr_printf(args->hdr,"##INFO=",args->ld_annot[VCFBUF_LD_IDX_R2],args->ld_annot_pos[VCFBUF_LD_IDX_R2]); bcf_hdr_printf(args->hdr,"##INFO=",args->ld_annot_pos[VCFBUF_LD_IDX_R2],args->ld_annot[VCFBUF_LD_IDX_R2]); } if ( args->ld_annot[VCFBUF_LD_IDX_LD] ) { bcf_hdr_printf(args->hdr,"##INFO=",args->ld_annot[VCFBUF_LD_IDX_LD],args->ld_annot_pos[VCFBUF_LD_IDX_LD]); bcf_hdr_printf(args->hdr,"##INFO=",args->ld_annot_pos[VCFBUF_LD_IDX_LD],args->ld_annot[VCFBUF_LD_IDX_LD]); } if ( args->ld_annot[VCFBUF_LD_IDX_HD] ) { bcf_hdr_printf(args->hdr,"##INFO=",args->ld_annot[VCFBUF_LD_IDX_HD],args->ld_annot_pos[VCFBUF_LD_IDX_HD]); bcf_hdr_printf(args->hdr,"##INFO=",args->ld_annot_pos[VCFBUF_LD_IDX_HD],args->ld_annot[VCFBUF_LD_IDX_HD]); } } if ( bcf_hdr_write(args->out_fh, args->hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); args->ld_filter_id = -1; if ( args->ld_filter && strcmp(".",args->ld_filter) ) args->ld_filter_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, args->ld_filter); args->vcfbuf = vcfbuf_init(args->hdr, args->ld_win); if ( args->ld_max_set[VCFBUF_LD_IDX_R2] ) vcfbuf_set(args->vcfbuf,LD_MAX_R2,args->ld_max[VCFBUF_LD_IDX_R2]); if ( args->ld_max_set[VCFBUF_LD_IDX_LD] ) vcfbuf_set(args->vcfbuf,LD_MAX_LD,args->ld_max[VCFBUF_LD_IDX_LD]); if ( args->ld_max_set[VCFBUF_LD_IDX_HD] ) vcfbuf_set(args->vcfbuf,LD_MAX_HD,args->ld_max[VCFBUF_LD_IDX_HD]); if ( args->rand_missing || (args->nsites_mode && !strcasecmp(args->nsites_mode,"rand")) ) { fprintf(stderr,"Using random seed: %d\n",args->rseed); hts_srand48(args->rseed); } if ( args->rand_missing ) vcfbuf_set(args->vcfbuf,LD_RAND_MISSING,1); if ( args->nsites ) { vcfbuf_set(args->vcfbuf,PRUNE_NSITES,args->nsites); vcfbuf_set(args->vcfbuf,PRUNE_NSITES_MODE,args->nsites_mode); } if ( args->af_tag ) vcfbuf_set(args->vcfbuf,PRUNE_AF_TAG,args->af_tag); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); vcfbuf_destroy(args->vcfbuf); bcf_sr_destroy(args->sr); free(args); } static void flush(args_t *args, int flush_all) { bcf1_t *rec; while ( (rec = vcfbuf_flush(args->vcfbuf, flush_all)) ) if ( bcf_write1(args->out_fh, args->hdr, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } static void process(args_t *args) { int i, filter = 0; bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( args->filter ) { int ret = filter_test(args->filter, rec, NULL); if ( args->filter_logic==FLT_INCLUDE ) { if ( !ret ) filter = 1; } else if ( ret ) filter = 1; if ( filter && !args->keep_sites ) return; } bcf_sr_t *sr = bcf_sr_get_reader(args->sr, 0); if ( args->ld_mask ) { vcfbuf_ld_t ld; if ( vcfbuf_ld(args->vcfbuf, rec, &ld) == 0 ) { int pass = 1; for (i=0; ild_max_set[i] || ld.val[i] <= args->ld_max[i] ) continue; pass = 0; break; } if ( !pass ) { if ( !args->ld_filter ) return; // hard filter if ( args->ld_filter_id >= 0 ) // soft FILTER bcf_add_filter(args->hdr, rec, args->ld_filter_id); } for (i=0; ild_annot[i] ) { int32_t pos = ld.rec[i]->pos+1; bcf_update_info_int32(args->hdr, rec, args->ld_annot_pos[i], &pos, 1); } } for (i=0; ild_annot[i] ) { float val = ld.val[i]; bcf_update_info_float(args->hdr, rec, args->ld_annot[i], &val, 1); } } } } if ( filter ) vcfbuf_set(args->vcfbuf,LD_FILTER1,1); sr->buffer[0] = vcfbuf_push(args->vcfbuf, rec); flush(args,0); } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->output_fname = "-"; args->ld_win = -100e3; args->nsites_mode = "maxAF"; args->rseed = time(NULL); args->clevel = -1; static struct option loptions[] = { {"keep-sites",no_argument,NULL,'k'}, {"randomize-missing",no_argument,NULL,1}, {"AF-tag",required_argument,NULL,2}, {"random-seed",required_argument,NULL,3}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"annotate",required_argument,NULL,'a'}, {"set-filter",required_argument,NULL,'f'}, {"max",required_argument,NULL,'m'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"nsites-per-win",required_argument,NULL,'n'}, {"nsites-per-win-mode",required_argument,NULL,'N'}, {"window",required_argument,NULL,'w'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "vr:R:t:T:m:o:O:a:f:i:e:n:N:w:kW::",loptions,NULL)) >= 0) { switch (c) { case 1 : args->rand_missing = 1; break; case 2 : args->af_tag = optarg; break; case 3 : args->rseed = strtol(optarg,&tmp,10); if ( tmp==optarg || *tmp ) error("Could not parse: --random-seed %s\n", optarg); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'k': args->keep_sites = 1; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'a': { int n, i; char **tag = hts_readlist(optarg,0,&n); if ( !n || !tag ) error("Could not parse: --annotate %s\n",optarg); for (i=0; ild_annot_pos[VCFBUF_LD_IDX_R2] = "POS_R2"; args->ld_annot[VCFBUF_LD_IDX_R2] = "R2"; } else if ( !strcasecmp("LD",tag[i]) ) { args->ld_annot_pos[VCFBUF_LD_IDX_LD] = "POS_LD"; args->ld_annot[VCFBUF_LD_IDX_LD] = "LD"; } else if ( !strcasecmp("HD",tag[i]) ) { args->ld_annot_pos[VCFBUF_LD_IDX_HD] = "POS_HD"; args->ld_annot[VCFBUF_LD_IDX_HD] = "HD"; } else error("The tag \"%s\" is not supported\n",tag[i]); free(tag[i]); } free(tag); args->ld_mask |= LD_ANNOTATE; } break; case 'f': args->ld_filter = optarg; break; case 'n': args->nsites = strtod(optarg,&tmp); if ( tmp==optarg || *tmp ) error("Could not parse: --nsites-per-win %s\n", optarg); break; case 'N': if ( !strcasecmp(optarg,"maxAF") ) args->nsites_mode = optarg; else if ( !strcasecmp(optarg,"1st") ) args->nsites_mode = optarg; else if ( !strcasecmp(optarg,"rand") ) args->nsites_mode = optarg; else error("The mode \"%s\" is not recognised\n",optarg); break; case 'm': if ( !strncasecmp("R2=",optarg,3) ) { args->ld_max_set[VCFBUF_LD_IDX_R2] = 1; args->ld_max[VCFBUF_LD_IDX_R2] = strtod(optarg+3,&tmp); } else if ( !strncasecmp("LD=",optarg,3) ) { args->ld_max_set[VCFBUF_LD_IDX_LD] = 1; args->ld_max[VCFBUF_LD_IDX_LD] = strtod(optarg+3,&tmp); } else if ( !strncasecmp("HD=",optarg,3) ) { args->ld_max_set[VCFBUF_LD_IDX_HD] = 1; args->ld_max[VCFBUF_LD_IDX_HD] = strtod(optarg+3,&tmp); } else { args->ld_max_set[VCFBUF_LD_IDX_R2] = 1; args->ld_max[VCFBUF_LD_IDX_R2] = strtod(optarg,&tmp); } if ( !tmp || *tmp ) error("Could not parse: --max %s\n", optarg); args->ld_mask |= LD_SET_MAX; break; case 'w': args->ld_win = strtod(optarg,&tmp); if ( !*tmp ) break; if ( tmp==optarg ) error("Could not parse: --window %s\n", optarg); else if ( !strcasecmp("bp",tmp) ) args->ld_win *= -1; else if ( !strcasecmp("kb",tmp) ) args->ld_win *= -1000; else if ( !strcasecmp("Mb",tmp) ) args->ld_win *= -1000000; else error("Could not parse: --window %s\n", optarg); break; case 'T': args->target_is_file = 1; // fall-through case 't': args->target = optarg; break; case 'R': args->region_is_file = 1; // fall-through case 'r': args->region = optarg; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); if ( !args->ld_mask && !args->nsites ) error("%sError: Expected pruning (--max,--nsites-per-win) or annotation (--annotate) options\n\n", usage_text()); if ( args->ld_filter && strcmp(".",args->ld_filter) && !(args->ld_mask & LD_SET_MAX) ) error("The --set-filter option requires --max.\n"); if ( args->keep_sites && args->nsites ) error("The --keep-sites option cannot be combined with --nsites-per-win\n"); if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else args->fname = argv[optind]; init_data(args); while ( bcf_sr_next_line(args->sr) ) process(args); flush(args,1); destroy_data(args); return 0; } bcftools-1.21/plugins/remove-overlaps.c000066400000000000000000000316021467060157400202370ustar00rootroot00000000000000/* Copyright (C) 2017-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "vcfbuf.h" #include "filter.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { filter_t *filter; char *filter_str; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) vcfbuf_t *vcfbuf; int argc, region_is_file, target_is_file, output_type, verbose, nrm, ntot, clevel; int reverse; char **argv, *region, *target, *fname, *output_fname, *mark_expr, *mark_tag, *missing_expr; htsFile *out_fh; BGZF *fh_bgzf; bcf_hdr_t *hdr; bcf_srs_t *sr; char *index_fn; int write_index, record_cmd_line; kstring_t kstr; } args_t; const char *about(void) { return "Remove, list or mark overlapping variants\n"; } static const char *usage_text(void) { return "\n" "About: Remove, list or mark overlapping variants.\n" "\n" "Usage: bcftools +remove-overlaps [OPTIONS]\n" "Plugin options:\n" " -M, --mark-tag TAG Mark -m sites with INFO/TAG\n" " -m, --mark EXPR Mark (if also -M is present) or remove sites [overlap]\n" " dup .. all duplicate sites\n" " overlap .. overlapping sites\n" " min(QUAL) .. sites with lowest QUAL until overlaps are resolved\n" " --missing EXPR Value to use for missing tags with -m 'min(QUAL)'\n" " 0 .. the default\n" " DP .. heuristics, scale maximum QUAL value proportionally to INFO/DP\n" " --reverse Apply the reverse logic, for example preserve duplicates instead of removing\n" "Standard options:\n" " -e, --exclude EXPR Exclude sites for which the expression is true\n" " -i, --include EXPR Include only sites for which the expression is true\n" " -o, --output FILE Write output to the FILE [standard output]\n" " -O, --output-type u|b|v|z|t[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level\n" " t: plain list of sites (chr,pos), tz: compressed list [v]\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " -t, --targets REGION Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --no-version Do not append version and command line to the header\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n"; } // duh: FT_TAB_TEXT is 0 :-/ static int is_text(int flag) { if ( flag==FT_TAB_TEXT || flag==FT_GZ ) return 1; return 0; } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->region ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->region, args->region_is_file)<0 ) error("Failed to read the regions: %s\n",args->region); } if ( args->target && bcf_sr_set_targets(args->sr, args->target, args->target_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->target); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); if ( is_text(args->output_type) ) { args->fh_bgzf = bgzf_open(args->output_fname, args->output_type&FT_GZ ? "wg" : "wu"); } else { args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); // todo: allow both INFO vs FILTER? if ( args->mark_tag ) { int ret = bcf_hdr_printf(args->hdr, "##INFO=",args->mark_tag); if ( ret!=0 ) error("Error adding the header tag INFO/%s\n",args->mark_tag); } if ( args->record_cmd_line ) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_remove-overlaps"); if ( bcf_hdr_write(args->out_fh, args->hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr,args->output_fname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); } args->vcfbuf = vcfbuf_init(args->hdr, 0); vcfbuf_set(args->vcfbuf,MARK,args->mark_expr); if ( args->missing_expr ) vcfbuf_set(args->vcfbuf,MARK_MISSING_EXPR,args->missing_expr); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( args->out_fh && hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); if ( args->fh_bgzf && bgzf_close(args->fh_bgzf)!=0 ) error("[%s] Error: close failed .. %s\n",__func__,args->output_fname); vcfbuf_destroy(args->vcfbuf); bcf_sr_destroy(args->sr); free(args->kstr.s); free(args); } static void flush(args_t *args, int flush_all) { bcf1_t *rec; while ( (rec=vcfbuf_flush(args->vcfbuf,flush_all)) ) { int keep = vcfbuf_get_val(args->vcfbuf,int,MARK) ? 0 : 1; if ( args->reverse ) keep = keep ? 0 : 1; if ( !keep ) { args->nrm++; if ( !args->mark_tag ) continue; bcf_update_info_flag(args->hdr,rec,args->mark_tag,NULL,1); } int ret; if ( is_text(args->output_type) ) { args->kstr.l = 0; ksprintf(&args->kstr,"%s\t%"PRIhts_pos"\n",bcf_seqname(args->hdr,rec),rec->pos+1); if ( args->kstr.l && bgzf_write(args->fh_bgzf, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); } else { ret = bcf_write1(args->out_fh, args->hdr, rec); if ( ret!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } } } static void process(args_t *args) { args->ntot++; bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( args->filter ) { int ret = filter_test(args->filter, rec, NULL); if ( args->filter_logic==FLT_INCLUDE ) { if ( !ret ) return; } else if ( ret ) return; } bcf_sr_t *sr = bcf_sr_get_reader(args->sr, 0); sr->buffer[0] = vcfbuf_push(args->vcfbuf, rec); flush(args,0); } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->output_fname = "-"; args->mark_expr = "overlap"; args->clevel = -1; args->record_cmd_line = 1; static struct option loptions[] = { {"mark-tag",required_argument,NULL,'M'}, {"mark",required_argument,NULL,'m'}, {"reverse",no_argument,NULL,1}, {"no-version",no_argument,NULL,2}, {"missing",required_argument,NULL,3}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "m:M:r:R:t:T:o:O:i:e:dW::",loptions,NULL)) >= 0) { switch (c) { case 'm': args->mark_expr = optarg; break; case 'M': args->mark_tag = optarg; break; case 1 : args->reverse = 1; break; case 2 : args->record_cmd_line = 0; break; case 3 : args->missing_expr = optarg; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'T': args->target_is_file = 1; // fall-through case 't': args->target = optarg; break; case 'R': args->region_is_file = 1; // fall-through case 'r': args->region = optarg; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; case 't': args->output_type = FT_TAB_TEXT; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1]=='z' ) { optarg++; args->output_type |= FT_GZ; } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( args->write_index && is_text(args->output_type) ) error("Cannot index text output\n"); if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else args->fname = argv[optind]; init_data(args); while ( bcf_sr_next_line(args->sr) ) process(args); flush(args,1); fprintf(stderr,"Processed/Removed\t%d\t%d\n",args->ntot,args->nrm); destroy_data(args); return 0; } bcftools-1.21/plugins/scatter.c000066400000000000000000000445651467060157400165720ustar00rootroot00000000000000/* The MIT License Copyright (C) 2020-2023 Giulio Genovese Author: Giulio Genovese Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include "bcftools.h" #include "htslib/khash_str2int.h" #include "regidx.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { htsFile *fh; // output file handle char *fname; // output file name char *index_fn; } subset_t; typedef struct { char *filter_str; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) void *hash; regidx_t *reg_idx; regitr_t *reg_itr; int argc, region_is_file, target_is_file, nsites, chunk_cnt, rec_cnt, scatter_is_file, output_type, n_threads, clevel; int regions_overlap, targets_overlap; char **argv, *region, *target, *scatter, *fname, *prefix, *extra, *output_dir; bcf_srs_t *sr; kstring_t str; subset_t *sets; int nsets, msets; int record_cmd_line; char **hts_opts; int nhts_opts; bcf_hdr_t *hdr; int write_index; } args_t; const char *about(void) { return "Scatter VCF by chunks or regions, creating multiple VCFs.\n"; } static const char *usage_text(void) { return "\n" "About: Split VCF by chunks or regions, creating multiple VCFs.\n" "\n" "Usage: bcftools +scatter [Options]\n" "Plugin options:\n" " -e, --exclude EXPR Exclude sites for which the expression is true\n" " -i, --include EXPR Select sites for which the expression is true\n" " --no-version Do not append version and command line to the header\n" " -o, --output DIR Write output to the directory DIR\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " --threads INT Use multithreading with INT worker threads [0]\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -t, --targets [^]REGION Similar to -r but streams rather than index-jumps. Exclude regions with \"^\" prefix\n" " -T, --targets-file [^]FILE Similar to -R but streams rather than index-jumps. Exclude regions with \"^\" prefix\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " -n, --nsites-per-chunk INT Keep N sites for each chunk\n" " -s, --scatter REGION Comma-separated list of regions defining variant windows for each output VCF\n" " -S, --scatter-file FILE Regions listed in a file with an optional second column used to name each output VCF.\n" " Variants from multiple regions can be assigned to the same output VCF.\n" " -x, --extra STRING Output records not overlapping listed regions in separate file\n" " -p, --prefix STRING Prepend string to output VCF names\n" " --hts-opts LIST Low-level options to pass to HTSlib, e.g. block_size=32768\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "Examples:\n" " # Scatter a VCF file by shards with 10000 variants each\n" " bcftools +scatter input.bcf -Ob -o dir -n 10000 -p part-\n" "\n" " # Scatter a VCF file by chromosomes\n" " bcftools +scatter input.bcf -Ob -o dir -s chr1,chr2,chr3,<...>,chr22,chrX -x other\n" "\n"; } void mkdir_p(const char *fmt, ...) HTS_FORMAT(HTS_PRINTF_FMT, 1, 2); // most of this code was inspired by Petr Danecek's code in regidx.c #define MAX_COOR_0 REGIDX_MAX // CSI and hts_itr_query limit, 0-based int regidx_parse_reg_name(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) return -1; // skip blank lines if ( *ss=='#' ) return -1; // skip comments char *se = ss; while ( *se && *se!=':' && !isspace(*se) ) se++; *chr_beg = ss; *chr_end = se-1; if ( *se != ':' ) { *beg = 0; *end = MAX_COOR_0; } else { ss = se+1; *beg = strtod(ss, &se); if ( ss==se ) { fprintf(stderr,"Could not parse reg line: %s\n", line); return -2; } if ( *beg==0 ) { fprintf(stderr,"Could not parse reg line, expected 1-based coordinate: %s\n", line); return -2; } (*beg)--; if ( !se[0] || isspace(se[0])) { *end = *beg; } else if ( se[0] == '-' && (!se[1] || isspace(se[1])) ) { *end = MAX_COOR_0; se++; } else { ss = se+1; *end = strtod(ss, &se); if ( ss==se ) *end = *beg; else if ( *end==0 ) { fprintf(stderr,"Could not parse reg line, expected 1-based coordinate: %s\n", line); return -2; } else (*end)--; } } ss = se; while ( *ss && isspace(*ss) ) ss++; if ( !ss[0] ) ss = (char *)line; int *idx = (int *)payload; args_t *args = (args_t *)usr; int ret = khash_str2int_get(args->hash, ss, idx); if (ret < 0) { hts_expand0(subset_t, args->nsets + 1, args->msets, args->sets); args->sets[args->nsets].fname = strdup(ss); *idx = khash_str2int_inc(args->hash, args->sets[args->nsets].fname); args->nsets++; } return 0; } static void open_set(subset_t *set, args_t *args) { int j; args->str.l = 0; kputs(args->output_dir, &args->str); if ( args->str.s[args->str.l-1] != '/' ) kputc('/', &args->str); int k, l = args->str.l; if (args->prefix) kputs(args->prefix, &args->str); kputs(set->fname, &args->str); for (k=l; kstr.l; k++) if ( isspace(args->str.s[k]) ) args->str.s[k] = '_'; if ( args->output_type & FT_BCF ) kputs(".bcf", &args->str); else if ( args->output_type & FT_GZ ) kputs(".vcf.gz", &args->str); else kputs(".vcf", &args->str); char wmode[8]; set_wmode(wmode,args->output_type,args->str.s,args->clevel); set->fh = hts_open(args->str.s, wmode); if ( set->fh == NULL ) error("[%s] Error: cannot write to \"%s\": %s\n", __func__, args->str.s, strerror(errno)); if ( args->n_threads > 0) hts_set_opt(set->fh, HTS_OPT_THREAD_POOL, args->sr->p); if ( args->hts_opts ) { hts_opt *opts = NULL; for (j=0; jnhts_opts; j++) if ( hts_opt_add(&opts, args->hts_opts[j]) ) error("Could not set the HTS option \"%s\"\n", args->hts_opts[j]); if ( hts_opt_apply(set->fh, opts) ) error("Could not apply the HTS options\n"); hts_opt_free(opts); } if ( !args->hdr ) { args->hdr = bcf_sr_get_header(args->sr, 0); if ( args->record_cmd_line ) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_plugin"); } if ( bcf_hdr_write(set->fh, args->hdr)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__, args->str.s); if ( init_index2(set->fh,args->hdr,args->str.s,&set->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->str.s); } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->region ) { args->sr->require_index = 1; bcf_sr_set_opt(args->sr, BCF_SR_REGIONS_OVERLAP, args->regions_overlap); if ( bcf_sr_set_regions(args->sr, args->region, args->region_is_file)<0 ) error("Failed to read the regions: %s\n", args->region); } if ( args->target ) { bcf_sr_set_opt(args->sr, BCF_SR_TARGETS_OVERLAP, args->targets_overlap); if ( bcf_sr_set_targets(args->sr, args->target, args->target_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->target); } if ( bcf_sr_set_threads(args->sr, args->n_threads)<0 ) error("Failed to create threads\n"); if ( !bcf_sr_add_reader(args->sr, args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); mkdir_p("%s/", args->output_dir); if (args->nsites) { args->nsets = 1; hts_expand0(subset_t, args->nsets, args->msets, args->sets); } else { args->hash = khash_str2int_init(); if (args->scatter_is_file) { args->reg_idx = regidx_init(args->scatter, regidx_parse_reg_name, NULL, sizeof(int), args); if ( !args->reg_idx ) exit(-1); } else { char *ss; for (ss = args->scatter; *ss; ss++) if (*ss == ',') *ss = '\n'; args->reg_idx = regidx_init_string(args->scatter, regidx_parse_reg_name, NULL, sizeof(int), args); for (ss = args->scatter; *ss; ss++) if (*ss == '\n') *ss = ','; } args->reg_itr = regitr_init(args->reg_idx); if (args->extra) { hts_expand0(subset_t, args->nsets + 1, args->msets, args->sets); args->sets[args->nsets].fname = strdup(args->extra); args->nsets++; } int i; for (i=0; insets; i++) open_set(&args->sets[i], args); } } static void destroy_data(args_t *args) { if (args->scatter) { khash_str2int_destroy(args->hash); regidx_destroy(args->reg_idx); regitr_destroy(args->reg_itr); } free(args->str.s); int i; for (i=0; insets; i++) { subset_t *set = &args->sets[i]; if (set->fname) { if ( args->write_index ) { if ( bcf_idx_save(set->fh)<0 ) { if ( hts_close(set->fh)!=0 ) error("Error: close failed .. %s\n", set->fname); error("Error: cannot write to index %s\n", set->index_fn); } free(set->index_fn); } if ( hts_close(set->fh)!=0 ) error("Error: close failed .. %s\n", set->fname); free(set->fname); } } for (i=0; inhts_opts; i++) free(args->hts_opts[i]); free(args->hts_opts); free(args->sets); bcf_sr_destroy(args->sr); free(args); } static void process(args_t *args) { bcf1_t *rec = bcf_sr_get_line(args->sr, 0); subset_t *set; if (args->nsites) { subset_t *set = &args->sets[0]; if (!args->rec_cnt) { args->str.l = 0; kputw(args->chunk_cnt, &args->str); set->fname = strdup(args->str.s); open_set(set, args); args->rec_cnt = 0; } if ( bcf_write(set->fh, args->hdr, rec)!=0 ) error("[%s] Error: failed to write the record\n", __func__); args->rec_cnt++; if (args->rec_cnt == args->nsites) { args->rec_cnt = 0; int err = 0; if ( args->write_index && bcf_idx_save(set->fh) < 0) err = 1; if ( hts_close(set->fh)!=0 ) error("Error: close failed .. %s\n", set->fname); if (err) error("Error: cannot write to index %s\n", set->index_fn); free(set->fname); set->fname = NULL; args->chunk_cnt++; } } else { if ( regidx_overlap(args->reg_idx, bcf_hdr_id2name(args->hdr, rec->rid), rec->pos, rec->pos, args->reg_itr) ) { while (regitr_overlap(args->reg_itr)) { int idx = regitr_payload(args->reg_itr, int); set = &args->sets[idx]; if ( bcf_write(set->fh, args->hdr, rec)!=0 ) error("[%s] Error: failed to write the record\n", __func__); } } else if (args->extra) { set = &args->sets[args->nsets-1]; if ( bcf_write(set->fh, args->hdr, rec)!=0 ) error("[%s] Error: failed to write the record\n", __func__); } } } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1, sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->record_cmd_line = 1; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"no-version",no_argument,NULL,1}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,2}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,3}, {"targets", required_argument, NULL,'t'}, {"targets-file", required_argument, NULL,'T'}, {"targets-overlap",required_argument,NULL,4}, {"nsites-per-chunk",required_argument,NULL,'n'}, {"scatter",required_argument,NULL,'s'}, {"scatter-file",required_argument,NULL,'S'}, {"extra",required_argument,NULL,'x'}, {"prefix",required_argument,NULL,'p'}, {"hts-opts",required_argument,NULL,5}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "e:i:o:O:r:R:t:T:n:s:S:x:p:W::h?", loptions, NULL)) >= 0) { switch (c) { case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 1 : args->record_cmd_line = 0; break; case 'o': args->output_dir = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 2 : args->n_threads = strtol(optarg, 0, 0); break; case 'r': args->region = optarg; break; case 'R': args->region = optarg; args->region_is_file = 1; break; case 3 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 't': args->target = optarg; break; case 'T': args->target = optarg; args->target_is_file = 1; break; case 4 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'n': args->nsites = strtod(optarg, &tmp); if ( tmp==optarg || *tmp ) error("Could not parse: --nsites-per-chunk %s\n", optarg); if ( args->nsites <= 0 ) error("Positive integer required: --nsites-per-chunk %s\n", optarg); break; case 's': args->scatter = optarg; break; case 'S': args->scatter = optarg; args->scatter_is_file = 1; break; case 'x': args->extra = optarg; break; case 'p': args->prefix = optarg; break; case 5 : args->hts_opts = hts_readlist(optarg, 0, &args->nhts_opts); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->output_dir ) error("Missing the -o option\n"); if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given\n"); if ( !args->nsites && !args->scatter ) error("Missing either the -n or one of the -s or -S options\n"); if ( args->nsites && args->scatter ) error("Only one of -n or either -s or -S can be given\n"); if ( args->nsites && args->extra ) error("Cannot use -x together with -n\n"); init_data(args); while ( bcf_sr_next_line(args->sr) ) process(args); destroy_data(args); return 0; } bcftools-1.21/plugins/setGT.c000066400000000000000000000633221467060157400161430ustar00rootroot00000000000000/* plugins/setGT.c -- set gentoypes to given values Copyright (C) 2015-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef int (*cmp_f)(double a, double b); static int cmp_eq(double a, double b) { return a==b ? 1 : 0; } static int cmp_le(double a, double b) { return a<=b ? 1 : 0; } static int cmp_ge(double a, double b) { return a>=b ? 1 : 0; } static int cmp_lt(double a, double b) { return ab ? 1 : 0; } typedef struct { bcf_hdr_t *in_hdr, *out_hdr; int32_t *gts, mgts, *iarr, miarr, *xarr, mxarr; int *arr, marr; uint64_t nchanged; int tgt_mask, new_mask, new_gt; filter_t *filter; char *filter_str; struct { int m_allele, M_allele, x_vaf_allele, *gt, *phased, ploidy; char *gt_str; } custom; int filter_logic, rand_seed; uint8_t *smpl_pass; double binom_val, rand_frac; char *binom_tag; cmp_f binom_cmp; } args_t; args_t *args = NULL; #define GT_MISSING 1 #define GT_PARTIAL (1<<1) #define GT_REF (1<<2) #define GT_MAJOR (1<<3) #define GT_PHASED (1<<4) #define GT_UNPHASED (1<<5) #define GT_ALL (1<<6) #define GT_QUERY (1<<7) #define GT_BINOM (1<<8) #define GT_MINOR (1<<9) #define GT_CUSTOM (1<<10) #define GT_X_VAF (1<<11) #define GT_RAND (1<<12) #define MINOR_ALLELE -1 #define MAJOR_ALLELE -2 #define X_VAF_ALLELE -3 const char *about(void) { return "Set genotypes: partially missing to missing, missing to ref/major allele, etc.\n"; } const char *usage(void) { return "About: Sets genotypes. The target genotypes can be specified as:\n" " ./. .. completely missing (\".\" or \"./.\", depending on ploidy)\n" " ./x .. partially missing (e.g., \"./0\" or \".|1\" but not \"./.\")\n" " . .. partially or completely missing\n" " a .. all genotypes\n" " b .. heterozygous genotypes failing two-tailed binomial test (example below)\n" " q .. select genotypes using -i/-e options\n" " r:FLOAT .. select randomly a proportion of FLOAT genotypes (can be combined with other modes)\n" " and the new genotype can be one of:\n" " . .. missing (\".\" or \"./.\", keeps ploidy)\n" " 0 .. reference allele (e.g. 0/0 or 0, keeps ploidy)\n" " c:GT .. custom genotype (e.g. 0/0, 0, 0/1, m/M, 0/X overrides ploidy)\n" " m .. minor (the second most common) allele as determined from INFO/AC or FMT/GT (e.g. 1/1 or 1, keeps ploidy)\n" " M .. major allele as determined from INFO/AC or FMT/GT (e.g. 1/1 or 1, keeps ploidy)\n" " X .. allele with bigger read depth as determined from FMT/AD\n" " p .. phase genotype (0/1 becomes 0|1)\n" " u .. unphase genotype and sort by allele (1|0 becomes 0/1)\n" "Usage: bcftools +setGT [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -e, --exclude EXPR Exclude a genotype if true (requires -t q)\n" " -i, --include EXPR include a genotype if true (requires -t q)\n" " -n, --new-gt TYPE Genotypes to set, see above\n" " -s, --seed INT Random seed to use with -t r [0]\n" " -t, --target-gt TYPE Genotypes to change, see above\n" "\n" "Example:\n" " # set missing genotypes (\"./.\") to phased ref genotypes (\"0|0\")\n" " bcftools +setGT in.vcf -- -t . -n 0p\n" "\n" " # set missing genotypes with DP>0 and GQ>20 to ref genotypes (\"0/0\")\n" " bcftools +setGT in.vcf -- -t q -n 0 -i 'GT=\".\" && FMT/DP>0 && GQ>20'\n" "\n" " # set partially missing genotypes to completely missing\n" " bcftools +setGT in.vcf -- -t ./x -n .\n" "\n" " # set heterozygous genotypes to 0/0 if binom.test(nAlt,nRef+nAlt,0.5)<1e-3\n" " bcftools +setGT in.vcf -- -t \"b:AD<1e-3\" -n 0\n" "\n" " # force unphased heterozygous genotype if binom.test(nAlt,nRef+nAlt,0.5)>0.1\n" " bcftools +setGT in.vcf -- -t ./x -n c:'m/M'\n" "\n"; } static void _parse_binom_expr_error(char *str) { error( "Error parsing the expression: %s\n" "Expected TAG CMP VAL, where\n" " TAG .. one of the format tags\n" " CMP .. operator, one of <, <=, >, >=\n" " VAL .. value\n" "For example:\n" " bcftools +setGT in.vcf -- -t \"b:AD>1e-3\" -n 0\n" "\n", str ); } void parse_binom_expr(args_t *args, char *str) { if ( str[1]!=':' ) _parse_binom_expr_error(str); char *beg = str+2; while ( *beg && isspace(*beg) ) beg++; if ( !*beg ) _parse_binom_expr_error(str); char *end = beg; while ( *end ) { if ( isspace(*end) || *end=='<' || *end=='=' || *end=='>' ) break; end++; } if ( !*end ) _parse_binom_expr_error(str); args->binom_tag = (char*) calloc(1,end-beg+1); memcpy(args->binom_tag,beg,end-beg); int tag_id = bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,args->binom_tag); if ( !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,tag_id) ) error("The FORMAT tag \"%s\" is not present in the VCF\n", args->binom_tag); while ( *end && isspace(*end) ) end++; if ( !*end ) _parse_binom_expr_error(str); if ( !strncmp(end,"<=",2) ) { args->binom_cmp = cmp_le; beg = end+2; } else if ( !strncmp(end,">=",2) ) { args->binom_cmp = cmp_ge; beg = end+2; } else if ( !strncmp(end,"==",2) ) { args->binom_cmp = cmp_eq; beg = end+2; } else if ( !strncmp(end,"<",1) ) { args->binom_cmp = cmp_lt; beg = end+1; } else if ( !strncmp(end,">",1) ) { args->binom_cmp = cmp_gt; beg = end+1; } else if ( !strncmp(end,"=",1) ) { args->binom_cmp = cmp_eq; beg = end+1; } else _parse_binom_expr_error(str); while ( *beg && isspace(*beg) ) beg++; if ( !*beg ) _parse_binom_expr_error(str); args->binom_val = strtod(beg, &end); while ( *end && isspace(*end) ) end++; if ( *end ) _parse_binom_expr_error(str); args->tgt_mask |= GT_BINOM; return; } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { args = (args_t*) calloc(1,sizeof(args_t)); args->in_hdr = in; args->out_hdr = out; char *tmp; int c; static struct option loptions[] = { {"include",required_argument,NULL,'i'}, {"exclude",required_argument,NULL,'e'}, {"new-gt",required_argument,NULL,'n'}, {"target-gt",required_argument,NULL,'t'}, {"seed",required_argument,NULL,'s'}, {NULL,0,NULL,0} }; while ((c = getopt_long(argc, argv, "?hn:t:i:e:s:",loptions,NULL)) >= 0) { switch (c) { case 's': args->rand_seed = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse: -s %s\n",optarg); break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'n': args->new_mask = 0; if ( strchr(optarg,'.') ) args->new_mask |= GT_MISSING; if ( strchr(optarg,'0') ) args->new_mask |= GT_REF; if ( strchr(optarg,'m') ) args->new_mask |= GT_MINOR; if ( strchr(optarg,'M') ) args->new_mask |= GT_MAJOR; if ( strchr(optarg,'X') ) args->new_mask |= GT_X_VAF; if ( strchr(optarg,'p') ) args->new_mask |= GT_PHASED; if ( strchr(optarg,'u') ) args->new_mask |= GT_UNPHASED; if ( !strncmp(optarg,"c:",2) ) { args->new_mask |= GT_CUSTOM; args->custom.gt_str = optarg; } if ( args->new_mask==0 ) error("Unknown parameter to --new-gt: %s\n", optarg); break; case 't': if ( !strcmp(optarg,".") ) args->tgt_mask |= GT_MISSING|GT_PARTIAL; if ( !strcmp(optarg,"./x") ) args->tgt_mask |= GT_PARTIAL; if ( !strcmp(optarg,"./.") ) args->tgt_mask |= GT_MISSING; if ( !strcmp(optarg,"a") ) args->tgt_mask |= GT_ALL; if ( !strcmp(optarg,"q") ) args->tgt_mask |= GT_QUERY; if ( !strcmp(optarg,"?") ) args->tgt_mask |= GT_QUERY; // for backward compatibility if ( !strncmp(optarg,"r:",2) ) { args->rand_frac = strtod(optarg+2,&tmp); if ( *tmp ) error("Could not parse: -t %s\n", optarg); if ( args->rand_frac<=0 || args->rand_frac>=1 ) error("Expected value between 0 and 1 with -t\n"); args->tgt_mask |= GT_RAND; } if ( strchr(optarg,'b') ) parse_binom_expr(args, strchr(optarg,'b')); if ( args->tgt_mask==0 ) error("Unknown parameter to --target-gt: %s\n", optarg); break; case 'h': case '?': default: fprintf(stderr,"%s", usage()); exit(1); break; } } if ( !args->new_mask ) error("Expected -n option\n"); if ( !args->tgt_mask ) error("Expected -t option\n"); if ( args->tgt_mask & GT_RAND ) { if ( args->tgt_mask==GT_RAND ) args->tgt_mask |= GT_ALL; hts_srand48(args->rand_seed); } if ( args->new_mask & GT_MISSING ) args->new_gt = bcf_gt_missing; if ( args->new_mask & GT_REF ) args->new_gt = args->new_mask>_PHASED ? bcf_gt_phased(0) : bcf_gt_unphased(0); if ( args->new_mask & GT_CUSTOM ) { char *ptr = args->custom.gt_str + 2; while ( *ptr ) { int allele; if ( *ptr=='m' ) { allele = MINOR_ALLELE; args->new_mask |= GT_MINOR; } else if ( *ptr=='M' ) { allele = MAJOR_ALLELE; args->new_mask |= GT_MAJOR; } else if ( *ptr=='X' ) { allele = X_VAF_ALLELE; args->new_mask |= GT_X_VAF; } else if ( *ptr=='/' || *ptr=='|' ) { if ( !args->custom.ploidy ) error("Could not parse the genotype: %s\n",args->custom.gt_str); args->custom.phased[args->custom.ploidy-1] = *ptr=='|' ? 1 : 0; ptr++; continue; } else { char *end; allele = strtol(ptr,&end,10); if ( end==ptr || (*end && *end!='/' && *end!='|') ) error("Could not parse the genotype: %s\n",args->custom.gt_str); ptr = end - 1; } args->custom.ploidy++; args->custom.gt = realloc(args->custom.gt,sizeof(*args->custom.gt)*args->custom.ploidy); args->custom.phased = realloc(args->custom.phased,sizeof(*args->custom.phased)*args->custom.ploidy); args->custom.gt[args->custom.ploidy-1] = allele; args->custom.phased[args->custom.ploidy-1] = 0; ptr++; } // the phasing sign comes before the allele, move to the correct one int i; for (i=args->custom.ploidy-1; i>0; i--) args->custom.phased[i] = args->custom.phased[i-1]; } if ( args->filter_str && !(args->tgt_mask>_QUERY) ) error("Expected -tq with -i/-e\n"); if ( !args->filter_str && args->tgt_mask>_QUERY ) error("Expected -i/-e with -tq\n"); if ( args->filter_str ) args->filter = filter_init(in,args->filter_str); // Check the existence of FORMAT/GT tag, add it if not present int id = bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,"GT"); if ( !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,id) ) bcf_hdr_printf(args->out_hdr, "##FORMAT="); if ( (args->new_mask & GT_X_VAF) && !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,"AD")) ) error("Error: the FORMAT/AD annotation does exist, cannot run with --new-gt %s\n",args->custom.gt_str); return 0; } // sets GT phase for a single sample, ngts is the ploidy static inline int phase_gt(int32_t *ptr, int ngts) { int j, changed = 0; for (j=0; j0 && ptr[l-1]>x ) { ptr[l] = ptr[l-1]; l--; } ptr[l] = x; } return changed; } // sets GT for a single sample, ngts is the ploidy, allele static inline int set_gt(int32_t *ptr, int ngts, int allele) { int j, changed = 0; for (j=0; jcustom.ploidy; i++) { if ( args->custom.gt[i]==MINOR_ALLELE ) new_allele = args->custom.m_allele; else if ( args->custom.gt[i]==MAJOR_ALLELE ) new_allele = args->custom.M_allele; else if ( args->custom.gt[i]==X_VAF_ALLELE ) new_allele = args->custom.x_vaf_allele==bcf_gt_missing ? nals : bcf_gt_allele(args->custom.x_vaf_allele); else new_allele = args->custom.gt[i]; if ( new_allele >= nals ) // cannot set, the requested index is bigger than there are alleles in ALT new_allele = bcf_gt_missing; else new_allele = args->custom.phased[i] ? bcf_gt_phased(new_allele) : bcf_gt_unphased(new_allele); if ( ptr[i]==new_allele ) continue; ptr[i] = new_allele; changed = 1; } while ( i args->rand_frac ? 1 : 0; // reversed random draw } bcf1_t *process(bcf1_t *rec) { if ( !rec->n_sample ) return rec; int ngts = bcf_get_genotypes(args->in_hdr, rec, &args->gts, &args->mgts); ngts /= rec->n_sample; int i, j, changed = 0; if ( args->new_mask & GT_CUSTOM ) { if ( args->custom.ploidy > ngts ) // increased ploidy, expand the array { if ( args->mgts < args->custom.ploidy * rec->n_sample ) { args->mgts = args->custom.ploidy * rec->n_sample; args->gts = (int32_t*)realloc(args->gts,args->mgts*sizeof(*args->gts)); } for (i=0; in_sample; i++) { int32_t *src = args->gts + (rec->n_sample-i-1)*ngts; int32_t *dst = args->gts + (rec->n_sample-i-1)*args->custom.ploidy; for (j=0; jcustom.ploidy; j++) dst[j] = bcf_int32_vector_end; } ngts = args->custom.ploidy; } } // Calculating allele frequency for each allele and determining major allele // only do this if use_major is true if ( args->new_mask & GT_MAJOR ) { int maxAC = -1, majorAllele = -1; hts_expand(int,rec->n_allele,args->marr,args->arr); int ret = bcf_calc_ac(args->in_hdr,rec,args->arr,BCF_UN_FMT); if ( ret<= 0 ) error("Could not calculate allele count at %s:%"PRId64"\n", bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); for (i=0; i < rec->n_allele; ++i) { if (args->arr[i] > maxAC) { maxAC = args->arr[i]; majorAllele = i; } } // replacing new_gt by major allele args->new_gt = args->new_mask & GT_PHASED ? bcf_gt_phased(majorAllele) : bcf_gt_unphased(majorAllele); if ( args->new_mask & GT_CUSTOM ) args->custom.M_allele = majorAllele; } if ( args->new_mask & GT_MINOR ) { hts_expand(int,rec->n_allele,args->marr,args->arr); int ret = bcf_calc_ac(args->in_hdr,rec,args->arr,BCF_UN_FMT); if ( ret<= 0 ) error("Could not calculate allele count at %s:%"PRId64"\n", bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); int imax = 0; for (i=1; in_allele; i++) if ( args->arr[imax] < args->arr[i] ) imax = i; int imax2 = imax>0 ? 0 : (rec->n_allele>1 ? 1 : 0); for (i=0; in_allele; i++) if ( i!=imax && args->arr[imax2] < args->arr[i] ) imax2 = i; // replacing new_gt by major allele args->new_gt = args->new_mask & GT_PHASED ? bcf_gt_phased(imax2) : bcf_gt_unphased(imax2); if ( args->new_mask & GT_CUSTOM ) args->custom.m_allele = imax2; } if ( args->new_mask & GT_X_VAF ) { if ( bcf_get_format_int32(args->in_hdr,rec,"AD",&args->xarr,&args->mxarr)==rec->n_allele*rec->n_sample ) { int32_t *src = args->xarr, *dst = args->xarr; for (i=0; in_sample; i++) { int jmax = -1; for (j=0; jn_allele; j++) { if ( src[j]==bcf_int32_vector_end ) break; if ( src[j]==bcf_int32_missing ) continue; if ( j==0 || src[jmax] < src[j] ) jmax = j; } *dst = jmax==-1 ? bcf_gt_missing : bcf_gt_unphased(jmax); src += rec->n_allele; dst++; } } else return rec; } int nbinom = 0; if ( args->tgt_mask & GT_BINOM ) { nbinom = bcf_get_format_int32(args->in_hdr, rec, args->binom_tag, &args->iarr, &args->miarr); if ( nbinom<0 ) nbinom = 0; nbinom /= rec->n_sample; } // replace gts if ( nbinom && ngts>=2 ) // only diploid genotypes are considered: higher ploidy ignored further, haploid here { if ( args->filter ) filter_test(args->filter,rec,(const uint8_t **)&args->smpl_pass); for (i=0; in_sample; i++) { if ( args->smpl_pass ) { if ( !args->smpl_pass[i] && args->filter_logic==FLT_INCLUDE ) continue; if ( args->smpl_pass[i] && args->filter_logic==FLT_EXCLUDE ) continue; } int32_t *ptr = args->gts + i*ngts; if ( bcf_gt_is_missing(ptr[0]) || bcf_gt_is_missing(ptr[1]) || ptr[1]==bcf_int32_vector_end ) continue; if ( ptr[0]==ptr[1] ) continue; // a hom int ia = bcf_gt_allele(ptr[0]); int ib = bcf_gt_allele(ptr[1]); if ( ia>=nbinom || ib>=nbinom ) error("The sample %s has incorrect number of %s fields at %s:%"PRId64"\n", args->in_hdr->samples[i],args->binom_tag,bcf_seqname(args->in_hdr,rec),(int64_t) rec->pos+1); double prob = calc_binom_two_sided(args->iarr[i*nbinom+ia],args->iarr[i*nbinom+ib],0.5); if ( !args->binom_cmp(prob,args->binom_val) ) continue; if ( args->tgt_mask>_RAND && random_draw(args) ) continue; if ( args->new_mask>_UNPHASED ) changed += unphase_gt(ptr, ngts); else if ( args->new_mask==GT_PHASED ) changed += phase_gt(ptr, ngts); else if ( args->new_mask & GT_CUSTOM ) { if ( args->new_mask & GT_X_VAF ) args->custom.x_vaf_allele = args->xarr[i]; changed += set_gt_custom(args, ptr, ngts, rec->n_allele); } else if ( args->new_mask & GT_X_VAF ) changed += set_gt(ptr, ngts, args->xarr[i]); else changed += set_gt(ptr, ngts, args->new_gt); } } else if ( args->tgt_mask>_QUERY ) { int pass_site = filter_test(args->filter,rec,(const uint8_t **)&args->smpl_pass); if ( args->filter_logic==FLT_EXCLUDE ) { // -i can include a site but exclude a sample, -e exclude a site but include a sample if ( pass_site ) { if ( !args->smpl_pass ) return rec; pass_site = 0; for (i=0; in_sample; i++) { if ( args->smpl_pass[i] ) args->smpl_pass[i] = 0; else { args->smpl_pass[i] = 1; pass_site = 1; } } if ( !pass_site ) return rec; } else if ( args->smpl_pass ) for (i=0; in_sample; i++) args->smpl_pass[i] = 1; } else if ( !pass_site ) return rec; for (i=0; in_sample; i++) { if ( args->smpl_pass && !args->smpl_pass[i] ) continue; if ( args->tgt_mask>_RAND && random_draw(args) ) continue; if ( args->new_mask>_UNPHASED ) changed += unphase_gt(args->gts + i*ngts, ngts); else if ( args->new_mask==GT_PHASED ) changed += phase_gt(args->gts + i*ngts, ngts); else if ( args->new_mask & GT_CUSTOM ) { if ( args->new_mask & GT_X_VAF ) args->custom.x_vaf_allele = args->xarr[i]; changed += set_gt_custom(args, args->gts + i*ngts, ngts, rec->n_allele); } else if ( args->new_mask & GT_X_VAF ) changed += set_gt(args->gts + i*ngts, ngts, args->xarr[i]); else changed += set_gt(args->gts + i*ngts, ngts, args->new_gt); } } else { for (i=0; in_sample; i++) { int ploidy = 0, nmiss = 0; int32_t *ptr = args->gts + i*ngts; for (j=0; jtgt_mask>_ALL ) do_set = 1; else if ( args->tgt_mask>_PARTIAL && nmiss ) do_set = 1; else if ( args->tgt_mask>_MISSING && ploidy==nmiss ) do_set = 1; if ( !do_set ) continue; if ( args->tgt_mask>_RAND && random_draw(args) ) continue; if ( args->new_mask>_UNPHASED ) changed += unphase_gt(ptr, ngts); else if ( args->new_mask==GT_PHASED ) changed += phase_gt(ptr, ngts); else if ( args->new_mask & GT_CUSTOM ) { if ( args->new_mask & GT_X_VAF ) args->custom.x_vaf_allele = args->xarr[i]; changed += set_gt_custom(args, args->gts + i*ngts, ngts, rec->n_allele); } else if ( args->new_mask & GT_X_VAF ) changed += set_gt(ptr, ngts, args->xarr[i]); else changed += set_gt(ptr, ngts, args->new_gt); } } args->nchanged += changed; if ( changed ) { int ret = bcf_update_genotypes(args->out_hdr, rec, args->gts, ngts*rec->n_sample); if ( ret!=0 ) error("Error: failed to update genotypes at %s:%"PRIhts_pos"\n",bcf_seqname(args->in_hdr,rec),rec->pos+1); } return rec; } void destroy(void) { fprintf(stderr,"Filled %"PRId64" alleles\n", args->nchanged); free(args->custom.gt); free(args->custom.phased); free(args->binom_tag); if ( args->filter ) filter_destroy(args->filter); free(args->arr); free(args->iarr); free(args->xarr); free(args->gts); free(args); } bcftools-1.21/plugins/smpl-stats.c000066400000000000000000000436401467060157400172250ustar00rootroot00000000000000/* The MIT License Copyright (c) 2018-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include // for isatty #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { uint32_t npass, // number of genotypes passing the filter nnon_ref, // number of non-reference genotypes nhomRR, nhomAA, nhemi, nhet, nSNV, nIndel, nmissing, nsingleton, // het different from everyone else nts, ntv; // number of transitions and transversions } stats_t; typedef struct { stats_t *stats, site_stats; filter_t *filter; char *expr; } flt_stats_t; typedef struct { int argc, filter_logic, regions_is_file, targets_is_file; int nflt_str; char *filter_str, **flt_str; char **argv, *output_fname, *fname, *regions, *targets; bcf_srs_t *sr; bcf_hdr_t *hdr; flt_stats_t *filters; int nfilters, nsmpl; int32_t *gt_arr, *ac; int mgt_arr, mac; } args_t; args_t args; const char *about(void) { return "Calculate basic per-sample stats scanning over a range of thresholds simultaneously.\n"; } static const char *usage_text(void) { return "\n" "About: Calculates basic per-sample stats. Use curly brackets to scan a range of values simultaneously\n" "Usage: bcftools +smpl-stats [Plugin Options]\n" "Plugin options:\n" " -e, --exclude EXPR exclude sites and samples for which the expression is true\n" " -i, --include EXPR include sites and samples for which the expression is true\n" " -o, --output FILE output file name [stdout]\n" " -r, --regions REG restrict to comma-separated list of regions\n" " -R, --regions-file FILE restrict to regions listed in a file\n" " -t, --targets REG similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE similar to -R but streams rather than index-jumps\n" "\n" "Example:\n" " bcftools +smpl-stats -i 'GQ>{10,20,30,40,50}' file.bcf\n" "\n"; } static void parse_filters(args_t *args) { if ( !args->filter_str ) return; int mflt = 1; args->nflt_str = 1; args->flt_str = (char**) malloc(sizeof(char*)); args->flt_str[0] = strdup(args->filter_str); while (1) { int i, expanded = 0; for (i=args->nflt_str-1; i>=0; i--) { char *exp_beg = strchr(args->flt_str[i], '{'); if ( !exp_beg ) continue; char *exp_end = strchr(exp_beg+1, '}'); if ( !exp_end ) error("Could not parse the expression: %s\n", args->filter_str); char *beg = exp_beg+1, *mid = beg; while ( midflt_str[i], exp_beg - args->flt_str[i], &tmp); kputsn(beg, mid - beg, &tmp); kputs(exp_end+1, &tmp); args->nflt_str++; hts_expand(char*, args->nflt_str, mflt, args->flt_str); args->flt_str[args->nflt_str-1] = tmp.s; beg = ++mid; } expanded = 1; free(args->flt_str[i]); memmove(&args->flt_str[i], &args->flt_str[i+1], (args->nflt_str-i-1)*sizeof(*args->flt_str)); args->nflt_str--; args->flt_str[args->nflt_str] = NULL; } if ( !expanded ) break; } fprintf(stderr,"Collecting data for %d filtering expressions\n", args->nflt_str); } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets && bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); parse_filters(args); int i; if ( !args->nflt_str ) { args->filters = (flt_stats_t*) calloc(1, sizeof(flt_stats_t)); args->nfilters = 1; args->filters[0].expr = strdup("all"); } else { args->nfilters = args->nflt_str; args->filters = (flt_stats_t*) calloc(args->nfilters, sizeof(flt_stats_t)); for (i=0; infilters; i++) { args->filters[i].filter = filter_init(args->hdr, args->flt_str[i]); args->filters[i].expr = strdup(args->flt_str[i]); // replace tab's with spaces so that the output stays parsable char *tmp = args->filters[i].expr; while ( *tmp ) { if ( *tmp=='\t' ) *tmp = ' '; tmp++; } } } args->nsmpl = bcf_hdr_nsamples(args->hdr); for (i=0; infilters; i++) args->filters[i].stats = (stats_t*) calloc(args->nsmpl,sizeof(stats_t)); } static void destroy_data(args_t *args) { int i; for (i=0; infilters; i++) { if ( args->filters[i].filter ) filter_destroy(args->filters[i].filter); free(args->filters[i].stats); free(args->filters[i].expr); } free(args->filters); for (i=0; inflt_str; i++) free(args->flt_str[i]); free(args->flt_str); bcf_sr_destroy(args->sr); free(args->ac); free(args->gt_arr); free(args); } static void report_stats(args_t *args) { int i = 0,j; FILE *fh = !args->output_fname || !strcmp("-",args->output_fname) ? stdout : fopen(args->output_fname,"w"); if ( !fh ) error("Could not open the file for writing: %s\n", args->output_fname); fprintf(fh,"# CMD line shows the command line used to generate this output\n"); fprintf(fh,"# DEF lines define expressions for all tested thresholds\n"); fprintf(fh,"# FLT* lines report numbers for every threshold and every sample:\n"); fprintf(fh,"# %d) filter id\n", ++i); fprintf(fh,"# %d) sample\n", ++i); fprintf(fh,"# %d) number of genotypes which pass the filter\n", ++i); fprintf(fh,"# %d) number of non-reference genotypes\n", ++i); fprintf(fh,"# %d) number of homozygous ref genotypes (0/0 or 0)\n", ++i); fprintf(fh,"# %d) number of homozygous alt genotypes (1/1, 2/2, etc)\n", ++i); fprintf(fh,"# %d) number of heterozygous genotypes (0/1, 1/2, etc)\n", ++i); fprintf(fh,"# %d) number of hemizygous genotypes (0, 1, etc)\n", ++i); fprintf(fh,"# %d) number of SNVs\n", ++i); fprintf(fh,"# %d) number of indels\n", ++i); fprintf(fh,"# %d) number of singletons\n", ++i); fprintf(fh,"# %d) number of missing genotypes (./., ., ./0, etc)\n", ++i); fprintf(fh,"# %d) number of transitions (alt het genotypes such as \"1/2\" are counted twice)\n", ++i); fprintf(fh,"# %d) number of transversions (alt het genotypes such as \"1/2\" are counted twice)\n", ++i); fprintf(fh,"# %d) overall ts/tv\n", ++i); i = 0; fprintf(fh,"# SITE* lines report numbers for every threshold:\n"); fprintf(fh,"# %d) filter id\n", ++i); fprintf(fh,"# %d) number of sites which pass the filter\n", ++i); fprintf(fh,"# %d) number of SNVs\n", ++i); fprintf(fh,"# %d) number of indels\n", ++i); fprintf(fh,"# %d) number of singletons\n", ++i); fprintf(fh,"# %d) number of transitions (counted at most once at multiallelic sites)\n", ++i); fprintf(fh,"# %d) number of transversions (counted at most once at multiallelic sites)\n", ++i); fprintf(fh,"# %d) overall ts/tv\n", ++i); fprintf(fh, "CMD\t%s", args->argv[0]); for (i=1; iargc; i++) fprintf(fh, " %s",args->argv[i]); fprintf(fh, "\n"); for (i=0; infilters; i++) { flt_stats_t *flt = &args->filters[i]; fprintf(fh,"DEF\tFLT%d\t%s\n", i, flt->expr); } for (i=0; infilters; i++) { flt_stats_t *flt = &args->filters[i]; for (j=0; jnsmpl; j++) { fprintf(fh,"FLT%d", i); fprintf(fh,"\t%s",args->hdr->samples[j]); stats_t *stats = &flt->stats[j]; fprintf(fh,"\t%d", stats->npass); fprintf(fh,"\t%d", stats->nnon_ref); fprintf(fh,"\t%d", stats->nhomRR); fprintf(fh,"\t%d", stats->nhomAA); fprintf(fh,"\t%d", stats->nhet); fprintf(fh,"\t%d", stats->nhemi); fprintf(fh,"\t%d", stats->nSNV); fprintf(fh,"\t%d", stats->nIndel); fprintf(fh,"\t%d", stats->nsingleton); fprintf(fh,"\t%d", stats->nmissing); fprintf(fh,"\t%d", stats->nts); fprintf(fh,"\t%d", stats->ntv); fprintf(fh,"\t%.2f", stats->ntv ? (float)stats->nts/stats->ntv : INFINITY); fprintf(fh,"\n"); } fprintf(fh,"SITE%d", i); stats_t *stats = &flt->site_stats; fprintf(fh,"\t%d", stats->npass); fprintf(fh,"\t%d", stats->nSNV); fprintf(fh,"\t%d", stats->nIndel); fprintf(fh,"\t%d", stats->nsingleton); fprintf(fh,"\t%d", stats->nts); fprintf(fh,"\t%d", stats->ntv); fprintf(fh,"\t%.2f", stats->ntv ? (float)stats->nts/stats->ntv : INFINITY); fprintf(fh,"\n"); } if ( fclose(fh)!=0 ) error("Close failed: %s\n", (!args->output_fname || !strcmp("-",args->output_fname)) ? "stdout" : args->output_fname); } static inline int parse_genotype(int32_t *arr, int ngt1, int idx, int als[2]) { int32_t *ptr = arr + ngt1 * idx; if ( bcf_gt_is_missing(ptr[0]) ) return -1; als[0] = bcf_gt_allele(ptr[0]); if ( ngt1==1 || ptr[1]==bcf_int32_vector_end ) { ptr[1] = ptr[0]; return -2; } if ( bcf_gt_is_missing(ptr[1]) ) return -1; als[1] = bcf_gt_allele(ptr[1]); return 0; } static void process_record(args_t *args, bcf1_t *rec, flt_stats_t *flt) { int i,j; uint8_t *smpl_pass = NULL; // Find out which trios pass and if the site passes if ( flt->filter ) { int pass_site = filter_test(flt->filter, rec, (const uint8_t**) &smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return; pass_site = 0; for (i=0; insmpl; i++) { if ( smpl_pass[i] ) smpl_pass[i] = 0; else { smpl_pass[i] = 1; pass_site = 1; } } if ( !pass_site ) return; } else for (i=0; insmpl; i++) smpl_pass[i] = 1; } else if ( !pass_site ) return; } // Find out the allele counts. Try to use INFO/AC, if not present, determine from the genotypes hts_expand(int, rec->n_allele, args->mac, args->ac); if ( !bcf_calc_ac(args->hdr, rec, args->ac, BCF_UN_INFO|BCF_UN_FMT) ) return; // Get the genotypes int ngt = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); if ( ngt<0 ) return; int ngt1 = ngt / rec->n_sample; // For ts/tv: numeric code of the reference allele, -1 for insertions int ref = !rec->d.allele[0][1] ? bcf_acgt2int(*rec->d.allele[0]) : -1; int star_allele = -1; for (i=1; in_allele; i++) if ( !rec->d.allele[i][1] && rec->d.allele[i][0]=='*' ) { star_allele = i; break; } // Run the stats int site_pass = 0; int site_SNV = 0; int site_Indel = 0; int site_has_ts = 0; int site_has_tv = 0; int site_singleton = 0; for (i=0; insmpl; i++) { if ( smpl_pass && !smpl_pass[i] ) continue; stats_t *stats = &flt->stats[i]; // Determine the alternate allele and the genotypes, skip if any of the alleles is missing. int als[2]; int ret = parse_genotype(args->gt_arr, ngt1, i, als); if ( ret==-1 ) { stats->nmissing++; continue; } // missing allele if ( ret==-2 ) stats->nhemi++; else if ( als[0]!=als[1] ) stats->nhet++; else if ( als[0]==0 ) stats->nhomRR++; else stats->nhomAA++; stats->npass++; site_pass = 1; // Is there an alternate allele other than *? int has_nonref = 0; for (j=0; j<2; j++) { if ( als[j]==star_allele ) continue; if ( als[j]==0 ) continue; has_nonref = 1; } if ( !has_nonref ) continue; // only ref or * in this genotype stats->nnon_ref++; // Calculate ts/tv, count SNPs, indels. It does the right thing and handles also HetAA genotypes { int has_ts = 0, has_tv = 0, has_snv = 0, has_indel = 0; for (j=0; j<2; j++) { if ( als[j]==0 || als[j]==star_allele ) continue; if ( als[j] >= rec->n_allele ) error("The GT index is out of range at %s:%"PRId64" in %s\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,args->hdr->samples[j]); if ( args->ac[als[j]]==1 ) { stats->nsingleton++; site_singleton = 1; } int var_type = bcf_has_variant_type(rec, als[j], VCF_SNP|VCF_MNP|VCF_INDEL); if ( var_type < 0 ) error("bcf_has_variant_type() failed"); if ( var_type & (VCF_SNP|VCF_MNP) ) { int k = 0; while ( rec->d.allele[0][k] && rec->d.allele[als[j]][k] ) { if ( rec->d.allele[0][k]==rec->d.allele[als[j]][k] ) { k++; continue; } int alt = bcf_acgt2int(rec->d.allele[als[j]][k]); if ( abs(ref-alt)==2 ) has_ts = 1; else has_tv = 1; has_snv = 1; k++; } } else if ( var_type == VCF_INDEL ) has_indel = 1; } if ( has_ts ) { stats->nts++; site_has_ts = 1; } if ( has_tv ) { stats->ntv++; site_has_tv = 1; } if ( has_snv ) { stats->nSNV++; site_SNV = 1; } if ( has_indel ) { stats->nIndel++; site_Indel = 1; } } } flt->site_stats.npass += site_pass; flt->site_stats.nSNV += site_SNV; flt->site_stats.nIndel += site_Indel; flt->site_stats.nts += site_has_ts; flt->site_stats.ntv += site_has_tv; flt->site_stats.nsingleton += site_singleton; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; static struct option loptions[] = { {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"output",required_argument,NULL,'o'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {NULL,0,NULL,0} }; int c, i; while ((c = getopt_long(argc, argv, "o:s:i:e:r:R:t:T:",loptions,NULL)) >= 0) { switch (c) { case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else args->fname = argv[optind]; init_data(args); while ( bcf_sr_next_line(args->sr) ) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); for (i=0; infilters; i++) process_record(args, rec, &args->filters[i]); } report_stats(args); destroy_data(args); return 0; } bcftools-1.21/plugins/split-vep.c000066400000000000000000002114311467060157400170340ustar00rootroot00000000000000/* The MIT License Copyright (c) 2019-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include // for isatty #include #include #include #include #include #include #include #include #include #include "../bcftools.h" #include "../filter.h" #include "../convert.h" #include "../cols.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define SELECT_TR_ALL 0 #define SELECT_TR_WORST 1 #define SELECT_TR_EXPR 2 #define SELECT_CSQ_ANY -1 #define TR_OP_EQ 0 // = #define TR_OP_NE 1 // != #define TR_OP_RE 2 // ~ #define TR_OP_NR 3 // !~ #define GENES_RESTRICT 0 #define GENES_PRIORITIZE 1 typedef struct { regex_t *regex; char *type; int bcf_ht_type; } col2type_t; typedef struct { char *field; // the name of the VEP field, e.g. Consequence,Gene,etc. char *tag; // the name of the VCF tag: the annot_t.field with the -p prefix int idx; // 0-based index within the VEP annotation string int type; // annotation type, one of the BCF_HT_* types kstring_t str; // annotation value, ready to pass to bcf_update_info_* } annot_t; // for the use with --select TR typedef struct { char *field; // field name to use int idx; // field index int op; // one of the TR_OP_* operators regex_t *regex; // to be used with TR_OP_RE and TR_OP_NR char *value; // to be used with TR_OP_EQ and TR_OP_NE } select_tr_t; typedef struct { convert_t *convert; filter_t *filter; int argc, filter_logic, regions_is_file, targets_is_file, list_hdr, record_cmd_line, clevel; int regions_overlap, targets_overlap; kstring_t kstr; char *filter_str, *vep_tag, // the --annotation INFO tag to process *vep_format; // the format of VEP fields, used for error reporting only char **argv, *output_fname, *fname, *regions, *targets, *format_str; int output_type; htsFile *fh_vcf; BGZF *fh_bgzf; bcf_srs_t *sr; bcf_hdr_t *hdr, *hdr_out; int nfield; // number of all available VEP fields char **field; // list of all available VEP fields int nannot; // number of requested fields annot_t *annot; // requested fields int nscale; // number of items in the severity scale char **scale; // severity scale (list) int ncsq_str; // the length of csq_str allocated by bcf_get_info_string() char *csq_str; // the current bcf_get_info_string() result int csq_idx; // the index of the Consequence field; for the --select CSQ option char *severity, // the --severity scale option *select, // the --select option *column_str, // the --columns option *column_types, // the --columns-types option *annot_prefix, // the --annot-prefix option *genes_fname, // the --gene-list option *gene_fields_str; // the --gene-list-fields option int *gene_fields, ngene_fields; // the indices of --gene-list-fields names void *field2idx, // VEP field name to index, used in initialization *csq2severity, // consequence type to severity score *genes; // hashed --gene-list genes cols_t *cols_tr, // the current CSQ tag split into transcripts **cols_csq; // the current CSQ transcripts split into fields int ncols_csq,mcols_csq; // the number of cols_csq transcripts and the high-water mark int min_severity, max_severity; // ignore consequences outside this severity range int drop_sites; // the -x, --drop-sites option int select_tr; // one of SELECT_TR_* select_tr_t tr_expr; // with SELECT_TR_EXPR, see --select uint8_t *smpl_pass; // for filtering at sample level, used with -f int duplicate; // the -d, --duplicate option is set char *all_fields_delim; // the -A, --all-fields option is set float *farr; // helper arrays for bcf_update_* functions int32_t *iarr, *list_tr; int niarr,miarr, nfarr,mfarr, mlist_tr; col2type_t *column2type; int ncolumn2type; int raw_vep_request; // raw VEP tag requested and will need subsetting int allow_undef_tags; int genes_mode; // --gene-list +FILE, one of GENES_* mode, prioritize or restrict int print_header; char *index_fn; int write_index; } args_t; args_t args; const char *about(void) { return "Query structured annotations such as INFO/CSQ produced by VEP of INFO/BCSQ produced by bctools/csq.\n"; } static const char *default_severity(void) { return "# Default consequence substrings ordered in ascending order by severity.\n" "# Consequences with the same severity can be put on the same line in arbitrary order.\n" "# See also https://www.ensembl.org/info/genome/variation/prediction/predicted_data.html\n" "intergenic\n" "feature_truncation feature_elongation\n" "regulatory\n" "TF_binding_site TFBS\n" "downstream upstream\n" "non_coding_transcript non_coding\n" "intron NMD_transcript\n" "non_coding_transcript_exon\n" "5_prime_utr 3_prime_utr\n" "coding_sequence mature_miRNA\n" "stop_retained start_retained synonymous\n" "incomplete_terminal_codon\n" "splice_region\n" "missense inframe protein_altering\n" "transcript_amplification\n" "exon_loss\n" "disruptive\n" "start_lost stop_lost stop_gained frameshift\n" "splice_acceptor splice_donor\n" "transcript_ablation\n"; } static const char *default_column_types(void) { return "# Default CSQ subfield types, unlisted fields are type String.\n" "# Note that the name search is done using regular expressions, with\n" "# \"^\" and \"$\" appended automatically\n" // These positions are in fact not integers but strings such as 8586-8599/9231 // "cDNA_position Integer\n" // "CDS_position Integer\n" // "Protein_position Integer\n" "DISTANCE Integer\n" "STRAND Integer\n" "TSL Integer\n" "GENE_PHENO Integer\n" "HGVS_OFFSET Integer\n" ".*_POPS String\n" // e.g. MAX_AF_POPS "AF Float\n" ".*_AF Float\n" "MAX_AF_.* Float\n" "MOTIF_POS Integer\n" "MOTIF_SCORE_CHANGE Float\n" "existing_InFrame_oORFs Integer\n" "existing_OutOfFrame_oORFs Integer\n" "existing_uORFs Integer\n" "SpliceAI_pred_DP_.* Integer\n" "SpliceAI_pred_DS_.* Float\n"; } static const char *usage_text(void) { return "\n" "About: Query structured annotations such INFO/BCSQ or CSQ created by bcftools/csq or VEP. For more\n" " more information and pointers see http://samtools.github.io/bcftools/howtos/plugin.split-vep.html\n" "Usage: bcftools +split-vep [Plugin Options]\n" "Plugin options:\n" " -a, --annotation STR INFO annotation to parse, CSQ by default or BCSQ when not present [CSQ]\n" " -A, --all-fields DELIM Output all fields replacing the -a tag (\"%CSQ\" by default) in the -f\n" " filtering expression using the output field delimiter DELIM. This can be\n" " \"tab\", \"space\" or an arbitrary string.\n" " -c, --columns [LIST|-][:TYPE] Extract the fields listed either as 0-based indexes or names, \"-\" to extract all\n" " fields. See --columns-types for the defaults. Supported types are String/Str,\n" " Integer/Int and Float/Real. Unlisted fields are set to String. Existing header\n" " definitions will not be overwritten, remove first with `bcftools annotate -x`\n" " --columns-types -|FILE Pass \"-\" to print the default -c types or FILE to override the presets\n" " -d, --duplicate Output per transcript/allele consequences on a new line rather rather than\n" " as comma-separated fields on a single line\n" " -f, --format STR Create non-VCF output; similar to `bcftools query -f` but drops lines w/o consequence\n" " -g, --gene-list [+]FILE Consider only features listed in FILE, or prioritize if FILE is prefixed with \"+\"\n" " --gene-list-fields LIST Fields to match against by the -g list, by default gene names [SYMBOL,Gene,gene]\n" " -H, --print-header Print header, -HH to omit column indices\n" " -l, --list Parse the VCF header and list the annotation fields\n" " -p, --annot-prefix STR Before doing anything else, prepend STR to all CSQ fields to avoid tag name conflicts\n" " -s, --select TR:CSQ Select transcripts to extract by type and/or consequence severity. (See also -S and -x.)\n" " TR, transcript: all,worst,primary,pick,mane,EXPRESSION [all]\n" " CSQ, consequence: any,missense,missense+,etc [any]\n" " Where the transcript EXPRESSION is of the form \n" " FIELD: field name (e.g. \"CANONICAL\")\n" " OPERATOR: string comparison (=,!=), regex matching (~,!~)\n" " VALUE: required string value (e.g. \"YES\")\n" " The TR presets are defined as follows\n" " primary: CANONICAL=YES\n" " pick: PICK=1\n" " mane: MANE_SELECT!=\"\"\n" " -S, --severity -|FILE Pass \"-\" to print the default severity scale or FILE to override\n" " the default scale\n" " -u, --allow-undef-tags Print \".\" for undefined tags\n" " -x, --drop-sites Drop sites without consequences after -s is applied (the default with -f)\n" " -X, --keep-sites Do not drop sites without consequences (the default without -f)\n" "Common options:\n" " -e, --exclude EXPR Exclude sites and samples for which the expression is true\n" " -i, --include EXPR Include sites and samples for which the expression is true\n" " --no-version Do not append version and command line to the header\n" " -o, --output FILE Output file name [stdout]\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -r, --regions REG Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -t, --targets REG Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "Examples:\n" " # List available fields of the INFO/CSQ or INFO/BCSQ annotation\n" " bcftools +split-vep -l file.vcf.gz\n" "\n" " # List available fields of INFO/BCSQ when both INFO/CSQ and INFO/BCSQ are present\n" " bcftools +split-vep -l file.vcf.gz -a BCSQ\n" "\n" " # List the default severity scale\n" " bcftools +split-vep -S -\n" "\n" " # Extract Consequence, IMPACT and gene SYMBOL of the most severe consequence into\n" " # INFO annotations starting with the prefix \"vep\". For brevity, the columns can\n" " # be given also as 0-based indexes\n" " bcftools +split-vep -c Consequence,IMPACT,SYMBOL -s worst -p vep file.vcf.gz\n" " bcftools +split-vep -c 1-3 -s worst -p vep file.vcf.gz\n" "\n" " # Same as above but use the text output of the \"bcftools query\" format\n" " bcftools +split-vep -s worst -f '%CHROM %POS %Consequence %IMPACT %SYMBOL\\n' file.vcf.gz\n" "\n" " # Print all subfields (tab-delimited) in place of %CSQ, each consequence on a new line\n" " bcftools +split-vep -f '%CHROM %POS %CSQ\\n' -d -A tab file.vcf.gz\n" "\n" " # Extract gnomAD_AF subfield into a new INFO/gnomAD_AF annotation of Type=Float so that\n" " # numeric filtering can be used.\n" " bcftools +split-vep -c gnomAD_AF:Float file.vcf.gz -i'gnomAD_AF<0.001'\n" "\n" " # Similar to above, but add the annotation only if the consequence severity is missense\n" " # or equivalent. In order to drop sites with different consequences completely, provide\n" " # the -x option. See the online documentation referenced above for more examples.\n" " bcftools +split-vep -c gnomAD_AF:Float -s :missense file.vcf.gz\n" " bcftools +split-vep -c gnomAD_AF:Float -s :missense -x file.vcf.gz\n" "\n" " See also http://samtools.github.io/bcftools/howtos/plugin.split-vep.html\n" "\n"; } static void destroy_annot(args_t *args) { int i; for (i=0; inannot; i++) { annot_t *ann = &args->annot[i]; free(ann->field); free(ann->tag); free(ann->str.s); } free(args->annot); args->annot = NULL; args->nannot = 0; } static void expand_csq_expression(args_t *args, kstring_t *str) { if ( !args->all_fields_delim ) return; str->l = 0; kputc('%',str); kputs(args->vep_tag,str); char *ptr = strstr(args->format_str,str->s); if ( !ptr ) return; char *end = ptr + str->l, tmp = *end; if ( isalnum(tmp) || tmp=='_' || tmp=='.' ) return; *end = 0; str->l = 0; kputsn(args->format_str, ptr - args->format_str, str); int i; for (i=0; infield; i++) { if ( i>0 ) kputs(args->all_fields_delim, str); kputc('%', str); kputs(args->field[i], str); } *end = tmp; kputs(end, str); free(args->format_str); args->format_str = str->s; str->l = str->m = 0; str->s = NULL; } static void init_column2type(args_t *args) { int i, ntype = 0; char **type = NULL; if ( args->column_types && strcmp("-",args->column_types) ) type = hts_readlines(args->column_types, &ntype); else { char *str = strdup(default_column_types()); char *beg = str; while ( *beg ) { char *end = beg; while ( *end && *end!='\n' ) end++; char tmp = *end; *end = 0; ntype++; type = (char**) realloc(type,sizeof(*type)*ntype); type[ntype-1] = strdup(beg); if ( !tmp ) break; beg = end+1; } free(str); } if ( !type || !ntype ) error("Failed to parse the column types\n"); kstring_t tmp = {0,0,0}; for (i=0; incolumn2type++; args->column2type = (col2type_t*) realloc(args->column2type,sizeof(*args->column2type)*args->ncolumn2type); col2type_t *ct = &args->column2type[args->ncolumn2type-1]; ct->regex = (regex_t *) malloc(sizeof(regex_t)); if ( regcomp(ct->regex, tmp.s, REG_NOSUB) ) error("Error: fail to compile the column type regular expression \"%s\": %s\n", tmp.s,type[i]); ct->bcf_ht_type = -1; if ( !strcmp(ptr,"Float") ) ct->bcf_ht_type = BCF_HT_REAL; else if ( !strcmp(ptr,"Integer") ) ct->bcf_ht_type = BCF_HT_INT; else if ( !strcmp(ptr,"Flag") ) ct->bcf_ht_type = BCF_HT_FLAG; else if ( !strcmp(ptr,"String") ) ct->bcf_ht_type = BCF_HT_STR; if ( ct->bcf_ht_type==-1 ) error("Error: the column type \"%s\" is not supported: %s\n",ptr,type[i]); ct->type = strdup(ptr); } free(tmp.s); if ( !args->ncolumn2type ) error("Failed to parse the column types\n"); for (i=0; incolumn2type; i++) { if ( args->column2type[i].regex ) regfree(args->column2type[i].regex); free(args->column2type[i].regex); free(args->column2type[i].type); } free(args->column2type); args->ncolumn2type = 0; args->column2type = NULL; } static const char *get_column_type(args_t *args, char *field, int *type) { if ( !args->column2type ) init_column2type(args); int i; for (i=0; incolumn2type; i++) { int match = regexec(args->column2type[i].regex, field, 0,NULL,0) ? 0 : 1; if ( match ) { *type = args->column2type[i].bcf_ht_type; return args->column2type[i].type; } } *type = BCF_HT_STR; return "String"; } // Is the tag "field" present in the -f query string, such as '%CHROM %POS %field\n'? static int query_has_field(char *fmt, char *field, kstring_t *str) { str->l = 0; kputc('%',str); kputs(field,str); char end, *ptr = fmt; while ( ptr ) { ptr = strstr(ptr,str->s); if ( !ptr ) return 0; end = ptr[str->l]; if ( isalnum(end) || end=='_' || end=='.' ) { ptr++; continue; } break; } return 1; } /** The valid_tag array was generated with perl -le '@v = (split(//,q[_.]),"a"..."z","A"..."Z","0"..."9"); @a = (0) x 256; foreach $c (@v) { $a[ord($c)] = 1; } print join(", ",@a)' | fold -w 48 */ static const uint8_t valid_tag[256] = { 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 0, 0, 0, 0, 1, 0, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 }; static char *sanitize_field_name(const char *str) { if ( !strcmp(str,"1000G") ) return strdup(str); char *tmp; if ( str[0]=='.' || (str[0]>='0' && str[0]<='9') ) { // the field starts with an invalid character, prefix with underscore int len = 1 + strlen(str); tmp = (char*)malloc(len+1); tmp[0] = '_'; memcpy(tmp+1,str,len); } else tmp = strdup(str); char *out = tmp; while ( *tmp ) { if ( !valid_tag[(uint8_t)*tmp] ) *tmp = '_'; tmp++; } return out; } char *strdup_annot_prefix(args_t *args, const char *str) { char *out; if ( !args->annot_prefix ) { out = sanitize_field_name(str); return out; } int str_len = strlen(str); int prefix_len = strlen(args->annot_prefix); char *tmp = calloc(str_len+prefix_len+1,1); memcpy(tmp,args->annot_prefix,prefix_len); memcpy(tmp+prefix_len,str,str_len); out = sanitize_field_name(tmp); free(tmp); return out; } static void init_gene_list(args_t *args) { int i,j,ngene = 0; args->genes_mode = args->genes_fname[0]=='+' ? GENES_PRIORITIZE : GENES_RESTRICT; char *fname = args->genes_fname[0]=='+' ? args->genes_fname+1 : args->genes_fname; char **gene = hts_readlines(fname, &ngene); if ( !ngene || !gene ) error("Could not read the file provided with --gene-list %s\n",fname); args->genes = khash_str2int_init(); for (i=0; igenes,tmp,1) < 0 ) free(tmp); // duplicate gene name free(gene[i]); } free(gene); if ( !args->gene_fields_str ) args->gene_fields_str = "SYMBOL,Gene,gene"; gene = hts_readlist(args->gene_fields_str,0,&ngene); args->gene_fields = (int*)malloc(ngene*sizeof(*args->gene_fields)); for (i=0,j=0; ifield2idx,tmp,&args->gene_fields[j])==0 ) j++; free(tmp); free(gene[i]); } free(gene); args->ngene_fields = j; if ( !args->ngene_fields ) error("None of the \"%s\" fields is present in INFO/%s\n",args->gene_fields_str,args->vep_tag); } // The program was requested to create a text output as with `bcftools query -f`. For this we need to // determine the fields to be extracted from the formatting expression. Any subfields not listed in the // header will be added to column_str so that they can be added to the header static void parse_format_str(args_t *args) { int i; kstring_t str = {0,0,0}; // Special case: -A was given, extract all fields, for this the -a tag (%CSQ) must be present if ( args->all_fields_delim ) expand_csq_expression(args, &str); for (i=0; infield; i++) { if ( !query_has_field(args->format_str,args->field[i],&str) ) continue; int tag_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, args->field[i]); if ( bcf_hdr_idinfo_exists(args->hdr,BCF_HL_INFO,tag_id) ) fprintf(stderr,"Note: ambiguous key %%%s; using the %s subfield of %s, not the INFO/%s tag\n", args->field[i],args->field[i],args->vep_tag,args->field[i]); int olen = args->column_str ? strlen(args->column_str) : 0; int nlen = strlen(args->field[i]); args->column_str = (char*)realloc(args->column_str, olen + nlen + 2); if ( olen ) { memcpy(args->column_str+olen,",",1); olen++; } memcpy(args->column_str+olen,args->field[i],nlen); args->column_str[olen+nlen] = 0; } if ( query_has_field(args->format_str,args->vep_tag,&str) ) args->raw_vep_request = 1; free(str.s); } // The program was requested to extract one or more columns via -c. It can contain names, 0-based indexes or ranges of indexes static void parse_column_str(args_t *args) { if ( args->nannot ) return; // already called from parse_filter_str int i,j; int *column = NULL; int *types = NULL; if ( !strcmp("-",args->column_str) ) // all subfields { free(args->column_str); kstring_t str = {0,0,0}; ksprintf(&str,"0-%d",args->nfield-1); args->column_str = str.s; } char *ep = args->column_str; while ( *ep ) { char *tp, *bp = ep; while ( *ep && *ep!=',' ) ep++; char keep = *ep; *ep = 0; int type = -1; int idx_beg, idx_end; if ( !strcmp("-",bp) ) { kstring_t str = {0,0,0}; ksprintf(&str,"0-%d",args->nfield-1); if ( keep ) ksprintf(&str,",%s",ep+1); free(args->column_str); args->column_str = str.s; ep = str.s; continue; } char *tmp = strdup_annot_prefix(args, bp); // replace characters disallowed in tag names into underscores if ( khash_str2int_get(args->field2idx, bp, &idx_beg)==0 || khash_str2int_get(args->field2idx, tmp, &idx_beg)==0 ) { // either the original or sanitized version of the tag exists idx_end = idx_beg; } else if ( (tp=strrchr(bp,':')) ) // notice this requests the last occurrence of ':' { // there is a colon in the original string, expecting type specification *tp = 0; if ( khash_str2int_get(args->field2idx, bp, &idx_beg)!=0 ) { // even removing the part after the last colon does not give a valid tag error("No such column: \"%s\"\n", bp); } idx_end = idx_beg; *tp = ':'; if ( !strcasecmp(tp+1,"string") || !strcasecmp(tp+1,"str") ) type = BCF_HT_STR; else if ( !strcasecmp(tp+1,"float") || !strcasecmp(tp+1,"real") ) type = BCF_HT_REAL; else if ( !strcasecmp(tp+1,"integer") || !strcasecmp(tp+1,"int") ) type = BCF_HT_INT; else if ( !strcasecmp(tp+1,"flag") ) type = BCF_HT_FLAG; else error("The type \"%s\" nor the column \"%s\" recognised\n", tp+1,bp); } else { char *mp; idx_beg = strtol(bp,&mp,10); if ( !*mp ) idx_end = idx_beg; else if ( *mp=='-' ) idx_end = strtol(mp+1,&mp,10); if ( *mp ) { if ( *mp==':' ) { idx_end = idx_beg; if ( !strcasecmp(mp+1,"string") || !strcasecmp(mp+1,"str") ) type = BCF_HT_STR; else if ( !strcasecmp(mp+1,"float") || !strcasecmp(mp+1,"real") ) type = BCF_HT_REAL; else if ( !strcasecmp(mp+1,"integer") || !strcasecmp(mp+1,"int") ) type = BCF_HT_INT; else if ( !strcasecmp(mp+1,"flag") ) type = BCF_HT_FLAG; else error("The type \"%s\" nor the column \"%s\" recognised\n", mp+1,bp); } else if ( !strcmp(bp,args->vep_tag) ) { free(tmp); args->raw_vep_request = 1; if ( !keep ) break; ep++; continue; } else error("No such column: \"%s\"\n", bp); } } free(tmp); i = args->nannot; args->nannot += idx_end - idx_beg + 1; column = (int*)realloc(column,args->nannot*sizeof(*column)); types = (int*)realloc(types,args->nannot*sizeof(*types)); for (j=idx_beg; j<=idx_end; j++) { if ( j >= args->nfield ) error("The index is too big: %d\n", j); column[i] = j; types[i] = type; i++; } if ( !keep ) break; ep++; } // Prune duplicates for (i=0; inannot; i++) { for (j=0; jfield[column[i]],args->field[column[j]]) ) break; if ( i==j ) continue; // unique tag, no action needed args->nannot--; if ( i==args->nannot ) break; // the last one is to be skipped, we are done memmove(&column[i],&column[i+1],sizeof(*column)*(args->nannot-i)); i--; } // Now initizalize each annotation, add each column to the VCF header, and reconstruct // the column_str in case it will be needed later free(args->column_str); kstring_t str = {0,0,0}; args->annot = (annot_t*)calloc(args->nannot,sizeof(*args->annot)); for (i=0; inannot; i++) { annot_t *ann = &args->annot[i]; ann->type = types[i]; ann->idx = j = column[i]; ann->field = strdup(args->field[j]); ann->tag = strdup(args->field[j]); const char *type = "String"; if ( ann->type==BCF_HT_REAL ) type = "Float"; else if ( ann->type==BCF_HT_INT ) type = "Integer"; else if ( ann->type==BCF_HT_FLAG ) type = "Flag"; else if ( ann->type==BCF_HT_STR ) type = "String"; else if ( ann->type==-1 ) type = get_column_type(args, args->field[j], &ann->type); bcf_hdr_printf(args->hdr_out, "##INFO=", ann->tag,type,ann->field,args->vep_tag); if ( str.l ) kputc(',',&str); kputs(ann->tag,&str); } args->column_str = str.s; if ( args->raw_vep_request && args->select_tr==SELECT_TR_ALL ) args->raw_vep_request = 0; if ( args->raw_vep_request ) { args->nannot++; args->annot = (annot_t*)realloc(args->annot,args->nannot*sizeof(*args->annot)); annot_t *ann = &args->annot[args->nannot-1]; ann->type = BCF_HT_STR; ann->idx = -1; ann->field = strdup(args->vep_tag); ann->tag = strdup(args->vep_tag); memset(&ann->str,0,sizeof(ann->str)); } free(column); free(types); destroy_column2type(args); if ( bcf_hdr_sync(args->hdr_out)<0 ) error_errno("[%s] Failed to update header", __func__); } // Init filters. When neither -c,--columns nor -f,--format contains a VEP subfield used in the // filtering expression, and the subfield is not defined in the VCF header, then the filtering // will throw an error. We can be smart, detect these failures and such undefined subfields // as if the user passed them via the -c option. static void parse_filter_str(args_t *args) { args->filter = filter_parse(args->hdr_out, args->filter_str); if ( !args->filter ) error(NULL); // this type of error would have been reported int ret = filter_status(args->filter); if ( ret!=FILTER_OK ) { if ( ret!=FILTER_ERR_UNKN_TAGS ) error(NULL); // this type of error would have been reported // add the undefined tags to the -c string int ntags, i,j; const char **tags = filter_list_undef_tags(args->filter, &ntags); kstring_t str; str.s = args->column_str; str.l = str.m = str.s ? strlen(str.s) : 0; for (i=0; ifield2idx,tags[i],&j)!=0 ) error("Error: the tag \"%s\" is not defined in the VCF header or in INFO/%s\n",tags[i],args->vep_tag); if ( str.l ) kputc(',',&str); kputs(tags[i],&str); } args->column_str = str.s; parse_column_str(args); filter_destroy(args->filter); args->filter = filter_init(args->hdr_out, args->filter_str); } int ntags, i; const char **tags = filter_list_used_tags(args->filter, &ntags); for (i=0; ivep_tag) ) args->raw_vep_request = 1; } void init_select_tr_expr(args_t *args, const char *cnst_expr) { char *expr = strdup(cnst_expr); char *ptr = expr; while ( *ptr ) { if ( *ptr=='=' ) { *ptr = 0; args->tr_expr.field = strdup_annot_prefix(args,expr); *ptr = '='; int is_quoted = ( ptr[1]=='"' && ptr[strlen(ptr)-1]=='"' ) ? 1 : 0; args->tr_expr.value = strdup(ptr+1+is_quoted); if ( is_quoted ) args->tr_expr.value[strlen(args->tr_expr.value)-1] = 0; args->tr_expr.op = TR_OP_EQ; break; } else if ( *ptr=='~' ) { *ptr = 0; args->tr_expr.field = strdup_annot_prefix(args,expr); *ptr = '~'; int is_quoted = ( ptr[1]=='"' && ptr[strlen(ptr)-1]=='"' ) ? 1 : 0; args->tr_expr.value = strdup(ptr+1+is_quoted); if ( is_quoted ) args->tr_expr.value[strlen(args->tr_expr.value)-1] = 0; args->tr_expr.regex = (regex_t *) malloc(sizeof(regex_t)); if ( regcomp(args->tr_expr.regex, args->tr_expr.value, REG_NOSUB) ) error("Error: fail to compile the regular expression \"%s\"\n", args->tr_expr.value); args->tr_expr.op = TR_OP_RE; } else if ( *ptr=='!' && ptr[1]=='=' ) { *ptr = 0; args->tr_expr.field = strdup_annot_prefix(args,expr); *ptr = '!'; int is_quoted = ( ptr[2]=='"' && ptr[strlen(ptr)-1]=='"' ) ? 1 : 0; args->tr_expr.value = strdup(ptr+2+is_quoted); if ( is_quoted ) args->tr_expr.value[strlen(args->tr_expr.value)-1] = 0; args->tr_expr.op = TR_OP_NE; break; } else if ( *ptr=='!' && ptr[1]=='~' ) { *ptr = 0; args->tr_expr.field = strdup_annot_prefix(args,expr); *ptr = '!'; int is_quoted = ( ptr[2]=='"' && ptr[strlen(ptr)-1]=='"' ) ? 1 : 0; args->tr_expr.value = strdup(ptr+2+is_quoted); if ( is_quoted ) args->tr_expr.value[strlen(args->tr_expr.value)-1] = 0; args->tr_expr.regex = (regex_t *) malloc(sizeof(regex_t)); if ( regcomp(args->tr_expr.regex, args->tr_expr.value, REG_NOSUB) ) error("Error: fail to compile the regular expression \"%s\"\n", args->tr_expr.value); args->tr_expr.op = TR_OP_NR; break; } ptr++; } if ( !args->tr_expr.field ) error("Could not parse the expression: -s %s\n", cnst_expr); if ( khash_str2int_get(args->field2idx,args->tr_expr.field,&args->tr_expr.idx)!=0 ) error("The field \"%s\" was requested via \"%s\" but it is not present in INFO/%s: %s\n",args->tr_expr.field,expr,args->vep_tag,args->vep_format); free(expr); args->select_tr = SELECT_TR_EXPR; } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; bcf_sr_set_opt(args->sr,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets ) { bcf_sr_set_opt(args->sr,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); } if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); args->hdr_out = bcf_hdr_dup(args->hdr); // Check which one to use: BCSQ or CSQ if ( !args->vep_tag ) { int has_CSQ = bcf_hdr_idinfo_exists(args->hdr,BCF_HL_INFO,bcf_hdr_id2int(args->hdr,BCF_DT_ID,"CSQ")); int has_BCSQ = bcf_hdr_idinfo_exists(args->hdr,BCF_HL_INFO,bcf_hdr_id2int(args->hdr,BCF_DT_ID,"BCSQ")); if ( has_CSQ && has_BCSQ ) fprintf(stderr,"Warning: both INFO/CSQ and INFO/BCSQ exist, using INFO/CSQ\n"); if ( !has_CSQ && !has_BCSQ ) error("Error: Neither INFO/CSQ nor INFO/BCSQ was found in the header\n"); if ( has_CSQ ) args->vep_tag = "CSQ"; else if ( has_BCSQ ) args->vep_tag = "BCSQ"; } // Parse the header CSQ line, must contain Description with "Format: ..." declaration bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->hdr, BCF_HL_INFO, NULL, args->vep_tag, NULL); if ( !hrec ) error("The tag INFO/%s not found in the header\n", args->vep_tag); int ret = bcf_hrec_find_key(hrec, "Description"); if ( ret<0 ) error("No \"Description\" field was found for the tag INFO/%s in the header\n", args->vep_tag); char *format = strstr(hrec->vals[ret], "Format: "); if ( !format ) error("Expected \"Format: \" substring in the header INFO/%s/Description, found: %s\n", args->vep_tag,hrec->vals[ret]); format += 8; args->vep_format = strdup(format); char *ep = args->vep_format + strlen(args->vep_format) - 1; if ( *ep=='"' ) *ep = 0; ep = format; while ( *ep ) { char *bp = ep; while ( *ep && *ep!='|' && *ep!='"' && *ep!='(' ) ep++; // don't include bracket in "pos(1-based)" char tmp = *ep; *ep = 0; args->nfield++; args->field = (char**)realloc(args->field,args->nfield*sizeof(*args->field)); args->field[args->nfield-1] = strdup_annot_prefix(args,bp); if ( !tmp ) break; *ep = tmp; while ( *ep && *ep!='|' ) ep++; // skip bracket in "pos(1-based)" if ( *ep ) ep++; } if ( !args->nfield ) error("Could not parse Description of INFO/%s: %s\n", args->vep_tag,hrec->vals[ret]); args->field2idx = khash_str2int_init(); int i; for (i=0; infield; i++) { if ( khash_str2int_has_key(args->field2idx, args->field[i]) ) { fprintf(stderr,"Warning: duplicate INFO/%s key \"%s\"\n", args->vep_tag,args->field[i]); continue; } khash_str2int_set(args->field2idx, args->field[i], i); } // Severity scale kstring_t str = {0,0,0}; args->csq2severity = khash_str2int_init(); int severity = 0; if ( args->severity ) { kstring_t tmp = {0,0,0}; htsFile *fp = hts_open(args->severity,"r"); if ( !fp ) error("Cannot read %s\n", args->severity); while ( hts_getline(fp, KS_SEP_LINE, &tmp) > 0 ) { kputs(tmp.s, &str); kputc('\n', &str); } free(tmp.s); } else kputs(default_severity(),&str); ep = str.s; while ( *ep ) { if ( *ep=='#' ) { while ( *ep && *ep!='\n' ) { *ep = tolower(*ep); ep++; } if ( !*ep ) break; ep++; continue; } char *bp = ep; while ( *ep && !isspace(*ep) ) { *ep = tolower(*ep); ep++; } char tmp = *ep; *ep = 0; args->nscale++; args->scale = (char**) realloc(args->scale,args->nscale*sizeof(*args->scale)); args->scale[args->nscale-1] = strdup(bp); if ( !khash_str2int_has_key(args->csq2severity,args->scale[args->nscale-1]) ) khash_str2int_set(args->csq2severity,args->scale[args->nscale-1], severity); if ( !tmp ) break; if ( tmp=='\n' ) severity++; ep++; while ( *ep && isspace(*ep) ) ep++; } // Transcript and consequence selection if ( !args->select ) args->select = "all:any"; cols_t *cols = cols_split(args->select, NULL, ':'); char *sel_tr = cols->off[0][0] ? cols->off[0] : "all"; char *sel_csq = cols->n==2 && cols->off[1][0] ? cols->off[1] : "any"; // ... transcript selection if ( !strcasecmp(sel_tr,"all") ) args->select_tr = SELECT_TR_ALL; else if ( !strcasecmp(sel_tr,"worst") ) args->select_tr = SELECT_TR_WORST; else if ( !strcasecmp(sel_tr,"primary") ) init_select_tr_expr(args,"CANONICAL=YES"); else if ( !strcasecmp(sel_tr,"pick") ) init_select_tr_expr(args,"PICK=1"); else if ( !strcasecmp(sel_tr,"mane") ) init_select_tr_expr(args,"MANE_SELECT!=\"\""); else init_select_tr_expr(args,sel_tr); // ... consequence selection if ( !strcasecmp(sel_csq,"any") ) { args->min_severity = args->max_severity = SELECT_CSQ_ANY; } // to avoid unnecessary lookups else { int len = strlen(sel_csq); int severity, modifier = '='; if ( sel_csq[len-1]=='+' ) { modifier = '+'; sel_csq[len-1] = 0; } else if ( sel_csq[len-1]=='-' ) { modifier = '-'; sel_csq[len-1] = 0; } if ( khash_str2int_get(args->csq2severity, sel_csq, &severity)!=0 ) error("Error: the consequence \"%s\" is not recognised. Run \"bcftools +split-vep -S ?\" to see the default list.\n", sel_csq); if ( modifier=='=' ) { args->min_severity = severity; args->max_severity = severity; } else if ( modifier=='+' ) { args->min_severity = severity; args->max_severity = INT_MAX; } else if ( modifier=='-' ) { args->min_severity = 0; args->max_severity = severity; } } cols_destroy(cols); // The "Consequence" column to determine severity for filtering. The name of this column is hardwired for now, both VEP and bt/csq use the same name char *tmp = strdup_annot_prefix(args,"Consequence"); if ( khash_str2int_get(args->field2idx,tmp,&args->csq_idx)!=0 ) error("The field \"Consequence\" is not present in INFO/%s: %s\n", args->vep_tag,hrec->vals[ret]); free(tmp); if ( args->format_str ) parse_format_str(args); // Text output, e.g. bcftools +split-vep -f '%Consequence\n' if ( args->filter_str ) parse_filter_str(args); if ( args->column_str ) parse_column_str(args); // The --columns option was given, update the header if ( args->format_str ) { if ( !args->column_str && !args->select ) error("Error: No %s field selected in the formatting expression and -s not given: a typo?\n",args->vep_tag); args->convert = convert_init(args->hdr_out, NULL, 0, args->format_str); if ( !args->convert ) error("Could not parse the expression: %s\n", args->format_str); if ( args->allow_undef_tags ) convert_set_option(args->convert, allow_undef_tags, 1); if ( args->print_header>1 ) convert_set_option(args->convert, no_hdr_indices, 1); convert_set_option(args->convert, force_newline, 1); } if ( args->genes_fname ) init_gene_list(args); int max_unpack = BCF_UN_SHR; if ( args->convert ) max_unpack |= convert_max_unpack(args->convert); if ( args->filter ) max_unpack |= filter_max_unpack(args->filter); if ( !args->format_str ) max_unpack |= BCF_UN_FMT; // don't drop FMT fields on VCF input when VCF/BCF is output args->sr->max_unpack = max_unpack; if ( args->convert && (max_unpack & BCF_UN_FMT) ) convert_set_option(args->convert, subset_samples, &args->smpl_pass); free(str.s); } static void destroy_data(args_t *args) { free(args->list_tr); if ( args->tr_expr.regex ) regfree(args->tr_expr.regex); free(args->tr_expr.regex); free(args->tr_expr.field); free(args->tr_expr.value); free(args->vep_format); free(args->farr); free(args->iarr); free(args->kstr.s); free(args->column_str); free(args->format_str); cols_destroy(args->cols_tr); int i; for (i=0; imcols_csq; i++) cols_destroy(args->cols_csq[i]); free(args->cols_csq); for (i=0; inscale; i++) free(args->scale[i]); free(args->scale); for (i=0; infield; i++) free(args->field[i]); free(args->field); destroy_annot(args); free(args->gene_fields); if ( args->genes ) khash_str2int_destroy_free(args->genes); if ( args->field2idx ) khash_str2int_destroy(args->field2idx); if ( args->csq2severity ) khash_str2int_destroy(args->csq2severity); bcf_sr_destroy(args->sr); bcf_hdr_destroy(args->hdr_out); free(args->csq_str); if ( args->filter ) filter_destroy(args->filter); if ( args->convert ) convert_destroy(args->convert); if ( args->fh_vcf ) { if ( args->write_index ) { if ( bcf_idx_save(args->fh_vcf)<0 ) { if ( hts_close(args->fh_vcf)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->fh_vcf)!=0 ) error("Error: close failed .. %s\n",args->output_fname); } if ( args->fh_bgzf && bgzf_close(args->fh_bgzf)!=0 ) error("Error: close failed .. %s\n",args->output_fname); free(args); } static void list_header(args_t *args) { int i; for (i=0; infield; i++) printf("%d\t%s\n", i,args->field[i]); } static void csq_to_severity(args_t *args, char *csq, int *min_severity, int *max_severity, int exact_match) { *min_severity = INT_MAX; *max_severity = -1; char *ep = csq; while ( *ep ) { char *bp = ep; while ( *ep && *ep!='&' ) { *ep = tolower(*ep); ep++; } char tmp = *ep; *ep = 0; int i, severity = -1; if ( khash_str2int_get(args->csq2severity, bp, &severity)!=0 ) { for (i=0; inscale; i++) if ( strstr(bp,args->scale[i]) ) break; if ( i!=args->nscale ) khash_str2int_get(args->csq2severity, args->scale[i], &severity); else severity = args->nscale + 1; args->nscale++; args->scale = (char**) realloc(args->scale,args->nscale*sizeof(*args->scale)); args->scale[args->nscale-1] = strdup(bp); khash_str2int_set(args->csq2severity,args->scale[args->nscale-1], severity); if ( i==args->nscale ) fprintf(stderr,"Note: assigning a (high) severity score to a new consequence, use -S to override: %s -> %d\n",args->scale[args->nscale-1],args->nscale); if ( khash_str2int_get(args->csq2severity, bp, &severity)!=0 ) error("FIXME: failed to look up the consequence \"%s\"\n", bp); } if ( exact_match < 0 ) { if ( *min_severity > severity ) *min_severity = severity; if ( *max_severity < severity ) *max_severity = severity; } else { if ( severity==exact_match ) { *min_severity = *max_severity = severity; *ep = tmp; return; } } if ( !tmp ) break; *ep = tmp; ep++; } } static int csq_severity_pass(args_t *args, char *csq) { if ( args->min_severity==args->max_severity && args->min_severity==SELECT_CSQ_ANY ) return 1; int min_severity, max_severity, exact_match = args->min_severity==args->max_severity ? args->min_severity : -1; csq_to_severity(args, csq, &min_severity, &max_severity, exact_match); if ( max_severity < args->min_severity ) return 0; if ( min_severity > args->max_severity ) return 0; return 1; } static int get_matching_transcript(args_t *args, bcf1_t *rec, int *list) { int i, n = 0; for (i=0; incols_csq; i++) { cols_t *cols_csq = args->cols_csq[i]; if ( args->tr_expr.idx >= cols_csq->n ) error("Too few columns at %s:%"PRId64" .. %d (field %s) >= %d\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,args->tr_expr.idx,args->tr_expr.field,cols_csq->n); if ( args->tr_expr.op==TR_OP_EQ ) { if ( !strcmp(args->tr_expr.value,cols_csq->off[args->tr_expr.idx]) ) list[n++] = i; } else if ( args->tr_expr.op==TR_OP_NE ) { if ( strcmp(args->tr_expr.value,cols_csq->off[args->tr_expr.idx]) ) list[n++] = i; } else if ( args->tr_expr.op==TR_OP_RE ) { int match = regexec(args->tr_expr.regex,cols_csq->off[args->tr_expr.idx], 0,NULL,0) ? 0 : 1; if ( match ) list[n++] = i; } else if ( args->tr_expr.op==TR_OP_NR ) { int match = regexec(args->tr_expr.regex,cols_csq->off[args->tr_expr.idx], 0,NULL,0) ? 0 : 1; if ( !match ) list[n++] = i; } } return n; } static int get_worst_transcript(args_t *args, bcf1_t *rec) { int i, max_severity = -1, imax_severity = 0; for (i=0; incols_csq; i++) { cols_t *cols_csq = args->cols_csq[i]; if ( args->csq_idx >= cols_csq->n ) error("Too few columns at %s:%"PRId64" .. %d (Consequence) >= %d\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,args->csq_idx,cols_csq->n); char *csq = cols_csq->off[args->csq_idx]; int min, max; csq_to_severity(args, csq, &min, &max, -1); if ( max_severity < max ) { imax_severity = i; max_severity = max; } } return imax_severity; } static void annot_reset(annot_t *annot, int nannot) { int i; for (i=0; istr.l ) kputc(',',&ann->str); kputs(value, &ann->str); } static inline void parse_array_real(annot_t *ann, char *str, float **arr, int *marr, int *narr) { static int warned_type_err = 0; char *bp = str, *ep; float *ptr = *arr; int i, n = 1, m = *marr; for (i=0; *bp; bp++) if ( *bp == ',' ) n++; hts_expand(float*,n,m,ptr); i = 0; bp = str; while ( *bp ) { ptr[i] = strtod(bp, &ep); if ( bp==ep ) { if ( !warned_type_err && (ep[0]!='.' || (ep[1]!=',' && ep[1])) ) { fprintf(stderr,"Warning: Could not parse, not a numeric list %s=\"%s\", check the -c and --columns-types options.\n" " This message is printed only once.\n",ann->tag,str); warned_type_err = 1; } bcf_float_set_missing(ptr[i]); } i++; while ( *ep && *ep!=',' ) ep++; bp = *ep ? ep + 1 : ep; } *narr = i; *marr = m; *arr = ptr; } static inline void parse_array_int32(annot_t *ann, char *str, int **arr, int *marr, int *narr) { static int warned_type_err = 0; char *bp = str, *ep; int32_t *ptr = *arr; int i, n = 1, m = *marr; for (i=0; *bp; bp++) if ( *bp == ',' ) n++; hts_expand(int32_t*,n,m,ptr); i = 0; bp = str; while ( *bp ) { ptr[i] = strtol(bp, &ep, 10); if ( bp==ep ) { if ( !warned_type_err && (ep[0]!='.' || (ep[1]!=',' && ep[1])) ) { fprintf(stderr,"Warning: Could not parse, not a numeric list %s=\"%s\", check the -c and --columns-types options.\n" " This message is printed only once.\n",ann->tag,str); warned_type_err = 1; } ptr[i] = bcf_int32_missing; } i++; while ( *ep && *ep!=',' ) ep++; bp = *ep ? ep + 1 : ep; } *narr = i; *marr = m; *arr = ptr; } static void filter_and_output(args_t *args, bcf1_t *rec, int severity_pass, int all_missing) { int i, updated = 0; for (i=0; inannot; i++) { annot_t *ann = &args->annot[i]; if ( !ann->str.l ) continue; if ( ann->type==BCF_HT_REAL ) { parse_array_real(ann,ann->str.s,&args->farr,&args->mfarr,&args->nfarr); bcf_update_info_float(args->hdr_out,rec,ann->tag,args->farr,args->nfarr); } else if ( ann->type==BCF_HT_INT ) { parse_array_int32(ann,ann->str.s,&args->iarr,&args->miarr,&args->niarr); bcf_update_info_int32(args->hdr_out,rec,ann->tag,args->iarr,args->niarr); } else bcf_update_info_string(args->hdr_out,rec,ann->tag,ann->str.s); updated++; } if ( args->filter ) { int pass = filter_test(args->filter, rec, (const uint8_t**) &args->smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) return; } if ( args->format_str ) { if ( args->nannot ) { if ( args->drop_sites && (!updated || all_missing) ) return; // the standard case: using -f to print the CSQ subfields, skipping if missing } else { if ( !severity_pass ) return; // request to print only non-CSQ tags at sites that pass severity } args->kstr.l = 0; convert_line(args->convert, rec, &args->kstr); if ( args->kstr.l && bgzf_write(args->fh_bgzf, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); return; } if ( bcf_write(args->fh_vcf, args->hdr_out,rec)!=0 ) error("Failed to write to %s\n", args->output_fname); } static void restrict_csqs_to_genes(args_t *args) { int i,j, nhit = 0; // use iarr to mark transcripts from interesting genes hts_expand(int32_t,args->cols_tr->n,args->miarr,args->iarr); for (i=0; icols_tr->n; i++) { cols_t *cols_csq = args->cols_csq[i]; for (j=0; jngene_fields; j++) { int idx = args->gene_fields[j]; if ( idx >= cols_csq->n ) continue; if ( khash_str2int_has_key(args->genes,cols_csq->off[idx]) ) break; } if ( j < args->ngene_fields ) args->iarr[i] = 1, nhit++; else args->iarr[i] = 0; } if ( !nhit ) { if ( args->genes_mode==GENES_RESTRICT ) args->ncols_csq = 0; // no gene of interest return; } // remove all uninteresting genes by putting all cols_csq hits first i = 0, j = args->cols_tr->n - 1; while ( i < j ) { if ( args->iarr[i]==1 ) { i++; continue; } if ( args->iarr[j]==0 ) { j--; continue; } cols_t *tmp = args->cols_csq[i]; args->cols_csq[i] = args->cols_csq[j]; args->cols_csq[j] = tmp; char *tmp2 = args->cols_tr->off[i]; args->cols_tr->off[i] = args->cols_tr->off[j]; args->cols_tr->off[j] = tmp2; i++; j--; } args->ncols_csq = nhit; } // Split the VEP annotation by transcript and by field, then check if the number of subfields looks alright. // Unfortunately, we cannot enforce the number of subfields to match the header definition because that can // be variable: `bcftools csq` outputs different number of fields for different consequence types. // So we need to distinguish between this reasonable case and incorrectly formatted consequences such // as those reported for LoF_info subfield here https://github.com/Ensembl/ensembl-vep/issues/1351. static void split_csq_fields(args_t *args, bcf1_t *rec, int csq_str_len) { int i; args->cols_tr = cols_split(args->csq_str, args->cols_tr, ','); if ( args->cols_tr->n > args->mcols_csq ) { args->cols_csq = (cols_t**)realloc(args->cols_csq,args->cols_tr->n*sizeof(*args->cols_csq)); for (i=args->mcols_csq; icols_tr->n; i++) args->cols_csq[i] = NULL; args->mcols_csq = args->cols_tr->n; } args->ncols_csq = args->cols_tr->n; int nfield_diff = 0, need_fix = 0; for (i=0; icols_tr->n; i++) { args->cols_csq[i] = cols_split(args->cols_tr->off[i], args->cols_csq[i], '|'); if ( args->csq_idx >= args->cols_csq[i]->n ) need_fix = 1; if ( nfield_diff < abs(args->cols_csq[i]->n - args->nfield) ) nfield_diff = args->cols_csq[i]->n - args->nfield; } if ( !csq_str_len ) return; // called 2nd time, don't attempt to fix if ( !need_fix ) return; static int warned = 0; if ( !warned ) fprintf(stderr,"Warning: The number of INFO/%s subfields at %s:%"PRIhts_pos" does not match the header definition,\n" " expected %d subfields, found as %s as %d. (This warning is printed only once.)\n", args->vep_tag,bcf_seqname(args->hdr,rec),rec->pos+1,args->nfield,nfield_diff>0?"much":"few",args->nfield+nfield_diff); warned = 1; // One known failure mode is LoF_info subfield which can contain commas. Work around this by relying on // the number of pipe delimiters matching the header definition, replacing offending commas with slash // characters. This assumes that there is never a comma in the first subfield, otherwise it would be // impossible to distinguish between A|A,A,B,B|B and A|A,A,A,B|B int npipe = 0; while ( csq_str_len > 0 ) { csq_str_len--; if ( args->csq_str[csq_str_len]=='|' ) { npipe++; continue; } if ( args->csq_str[csq_str_len]!=',' ) continue; if ( npipe && !(npipe % (args->nfield-1)) ) { npipe = 0; continue; } // wholesome number of pipes encountered, this is a valid comma args->csq_str[csq_str_len] = '/'; } split_csq_fields(args,rec,0); // try once more } static void process_record(args_t *args, bcf1_t *rec) { int i,len = bcf_get_info_string(args->hdr,rec,args->vep_tag,&args->csq_str,&args->ncsq_str); if ( len<=0 ) { if ( !args->drop_sites ) { annot_reset(args->annot, args->nannot); filter_and_output(args,rec,1,1); } return; } split_csq_fields(args,rec,len); // restrict to -g genes if ( args->genes ) restrict_csqs_to_genes(args); // select transcripts of interest int nlist_tr = 0; hts_expand(int32_t,args->ncols_csq,args->mlist_tr,args->list_tr); if ( !args->ncols_csq ) nlist_tr = 0; // no transcripts left after -g applied else if ( args->select_tr==SELECT_TR_EXPR ) { nlist_tr = get_matching_transcript(args,rec,args->list_tr); } else if ( args->select_tr==SELECT_TR_WORST ) { nlist_tr = 1; args->list_tr[0] = get_worst_transcript(args,rec); } else { for (i=0; incols_csq; i++) args->list_tr[i] = i; nlist_tr = args->ncols_csq; } annot_reset(args->annot, args->nannot); int severity_pass = 0; // consequence severity requested via the -s option (BCF record may be output but not annotated) int all_missing = 1; // transcripts with all requested annotations missing will be discarded if -f was given static int too_few_fields_warned = 0; int j,ilist; for (ilist=0; ilistlist_tr[ilist]; cols_t *cols_csq = args->cols_csq[i]; if ( args->csq_idx >= cols_csq->n ) error("Too few columns at %s:%"PRId64" .. %d (Consequence) >= %d\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,args->csq_idx,cols_csq->n); char *csq = cols_csq->off[args->csq_idx]; if ( !csq_severity_pass(args, csq) ) continue; severity_pass = 1; for (j=0; jnannot; j++) { annot_t *ann = &args->annot[j]; if ( ann->idx >= cols_csq->n ) { if ( !too_few_fields_warned ) { fprintf(stderr, "Warning: fewer %s fields than expected at %s:%"PRId64", filling with dots. This warning is printed only once.\n", args->vep_tag,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); too_few_fields_warned = 1; } annot_append(ann, "."); continue; } char *ann_str = NULL; if ( ann->idx==-1 ) ann_str = args->cols_tr->off[i]; else if ( *cols_csq->off[ann->idx] ) ann_str = cols_csq->off[ann->idx]; if ( ann_str ) { annot_append(ann, ann_str); all_missing = 0; } else annot_append(ann, "."); // missing value } if ( args->duplicate ) { filter_and_output(args, rec, severity_pass, all_missing); annot_reset(args->annot, args->nannot); all_missing = 1; severity_pass = 0; } } if ( !severity_pass && args->drop_sites ) return; if ( !args->duplicate ) filter_and_output(args, rec, severity_pass, all_missing); } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->output_type = FT_VCF; args->record_cmd_line = 1; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"drop-sites",no_argument,0,'x'}, {"keep-sites",no_argument,0,'X'}, {"all-fields",no_argument,0,'A'}, {"duplicate",no_argument,0,'d'}, {"format",required_argument,0,'f'}, {"gene-list",required_argument,0,'g'}, {"gene-list-fields",required_argument,0,5}, {"annotation",required_argument,0,'a'}, {"annot-prefix",required_argument,0,'p'}, {"columns",required_argument,0,'c'}, {"columns-types",required_argument,0,1}, {"select",required_argument,0,'s'}, {"severity",required_argument,0,'S'}, {"list",no_argument,0,'l'}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,3}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,4}, {"no-version",no_argument,NULL,2}, {"allow-undef-tags",no_argument,0,'u'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c, drop_sites = -1; char *tmp; while ((c = getopt_long(argc, argv, "o:O:i:e:r:R:t:T:lS:s:c:p:a:f:dA:xXuHg:W::",loptions,NULL)) >= 0) { switch (c) { case 2 : args->record_cmd_line = 0; break; case 1 : args->column_types = optarg; break; case 'A': if ( !strcasecmp(optarg,"tab") ) args->all_fields_delim = "\t"; else if ( !strcasecmp(optarg,"space") ) args->all_fields_delim = " "; else args->all_fields_delim = optarg; break; case 'H': args->print_header++; break; case 'x': drop_sites = 1; break; case 'X': drop_sites = 0; break; case 'd': args->duplicate = 1; break; case 'f': args->format_str = strdup(optarg); break; case 'g': args->genes_fname = optarg; break; case 'a': args->vep_tag = optarg; break; case 'p': args->annot_prefix = optarg; break; case 'c': args->column_str = strdup(optarg); break; case 'S': args->severity = optarg; break; case 's': args->select = optarg; break; case 'l': args->list_hdr = 1; break; case 'u': args->allow_undef_tags = 1; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 3 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 5 : args->gene_fields_str = optarg; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( args->print_header && !args->format_str ) error("Error: the -H header printing is supported only with -f\n"); if ( args->all_fields_delim && !args->format_str ) error("Error: the -A option must be used with -f\n"); if ( args->severity && (!strcmp("?",args->severity) || !strcmp("-",args->severity)) ) error("%s", default_severity()); if ( args->column_types && !strcmp("-",args->column_types) ) error("%s", default_column_types()); if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; init_data(args); if ( args->list_hdr ) list_header(args); else { if ( !args->format_str && !args->column_str ) { if ( args->min_severity==SELECT_CSQ_ANY && args->max_severity==SELECT_CSQ_ANY ) { if ( args->select_tr!=SELECT_TR_EXPR ) error("Error: none of the -c,-f,-s options was given, why not use \"bcftools view\" instead?\n"); if ( drop_sites==-1 ) { // Note that this is just to compensate for a common user confusion and should not really be here: // the -s option is supposed to select from multiple transcripts, not to decide whether to keep or // drop a site. However, it is tempting to run `bcftools +split-vep -s mane` and expect on output // a VCF with sites impating MANE transcripts only. drop_sites = 1; } else if ( !drop_sites ) error("Error: the option -X has no effect without -c,-f, why not use \"bcftools view\" instead?\n"); } } if ( drop_sites==-1 ) drop_sites = args->format_str ? 1 : 0; args->drop_sites = drop_sites; if ( args->format_str ) { args->fh_bgzf = bgzf_open(args->output_fname, args->output_type&FT_GZ ? "wg" : "wu"); if ( args->print_header ) { args->kstr.l = 0; convert_header(args->convert,&args->kstr); if ( args->kstr.l && bgzf_write(args->fh_bgzf, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); } } else { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->fh_vcf = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->record_cmd_line ) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_split-vep"); if ( bcf_hdr_write(args->fh_vcf, args->hdr_out)!=0 ) error("Failed to write the header to %s\n", args->output_fname); if ( init_index2(args->fh_vcf,args->hdr,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); } while ( bcf_sr_next_line(args->sr) ) process_record(args, bcf_sr_get_line(args->sr,0)); } destroy_data(args); return 0; } bcftools-1.21/plugins/split.c000066400000000000000000000727041467060157400162540ustar00rootroot00000000000000/* Copyright (C) 2017-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Split VCF by sample(s) */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { char **rename; // use a new sample name (rename samples) int nsmpl, *smpl; // number of samples to keep and their indices in the input header htsFile *fh; // output file handle char *fname; // output file name filter_t *filter; bcf_hdr_t *hdr; char *index_fn; } subset_t; typedef struct { char *filter_str; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) uint8_t *info_tags, *fmt_tags; int ninfo_tags, minfo_tags, nfmt_tags, mfmt_tags, keep_info, keep_fmt; int argc, region_is_file, target_is_file, output_type, clevel; int regions_overlap, targets_overlap; char **argv, *region, *target, *fname, *output_dir, *keep_tags, *samples_fname, *groups_fname; void *unique_fnames; bcf_hdr_t *hdr_in, *hdr_out; bcf_srs_t *sr; subset_t *sets; int nsets, nhts_opts; char **hts_opts; int write_index; } args_t; const char *about(void) { return "Split VCF by sample, creating single- or multi-sample VCFs\n"; } static const char *usage_text(void) { return "\n" "About: Split VCF by sample, creating single- or multi-sample VCFs. The output files are named\n" " by sample names whenever possible, with the characters from the set [ \\t:/\\] replaced\n" " with \"_\", and a unique numeric suffix added in case of name clashes.\n" "Usage: bcftools +split [Options]\n" "Plugin options:\n" " -e, --exclude EXPR Exclude sites for which the expression is true (applied on the outputs)\n" " -G, --groups-file FILE Similar to -S, but the samples are split by group:\n" " \n" " # Create two output files (third column) with the second sample appearing\n" " # in both. The second column is for optional renaming of the samples, use\n" " # dash \"-\" to keep sample names unchanged\n" " sample1 - file1\n" " sample2 - file1,file2\n" " sample3 new-name3 file2\n" " \n" " -i, --include EXPR Include only sites for which the expression is true (applied on the outputs)\n" " -k, --keep-tags LIST List of tags to keep. By default all tags are preserved\n" " -o, --output DIR Write output to the directory DIR\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -S, --samples-file FILE List of samples to keep with up to three columns, one line per output file:\n" " \n" " # Create two output files, the first sample is the basename\n" " # of the new file\n" " sample1\n" " sample2,sample3\n" " \n" " # Optional second column to rename the samples\n" " sample1 new-name2\n" " sample2,sample3 new-name2,new-name3\n" " \n" " # Optional third column to provide output file base name, use dash \"-\"\n" " # to keep sample names unchanged\n" " sample1 new-name1 file1\n" " sample2,sample3 - file2\n" " \n" " -t, --targets REGION Similar to -r but streams rather than index-jumps\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --hts-opts LIST Low-level options to pass to HTSlib, e.g. block_size=32768\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "Examples:\n" " # Split a VCF file\n" " bcftools +split input.bcf -Ob -o dir\n" "\n" " # Exclude sites with missing or hom-ref genotypes\n" " bcftools +split input.bcf -Ob -o dir -i'GT=\"alt\"'\n" "\n" " # Keep all INFO tags but only GT and PL in FORMAT\n" " bcftools +split input.bcf -Ob -o dir -k INFO,FMT/GT,PL\n" "\n" " # Keep all FORMAT tags but drop all INFO tags\n" " bcftools +split input.bcf -Ob -o dir -k FMT\n" "\n"; } void mkdir_p(const char *fmt, ...) HTS_FORMAT(HTS_PRINTF_FMT, 1, 2); static char *create_unique_file_name(args_t *args, const char *template) { kstring_t str = {0,0,0}; kputs(template, &str); char *ptr = str.s; while ( *ptr ) { if ( *ptr==':' || *ptr=='\\' || *ptr=='/' || *ptr==' ' || *ptr=='\t' ) *ptr = '_'; ptr++; } size_t ori_len = str.l; int id = 0; if ( !args->unique_fnames ) args->unique_fnames = khash_str2int_init(); while ( khash_str2int_has_key(args->unique_fnames,str.s) ) { str.l = ori_len; kputc('-', &str); kputw(++id, &str); } khash_str2int_inc(args->unique_fnames, strdup(str.s)); return str.s; } void init_subsets(args_t *args) { int i,j, nsmpl = bcf_hdr_nsamples(args->hdr_in); if ( !args->samples_fname && !args->groups_fname ) { args->nsets = nsmpl; args->sets = (subset_t*) calloc(nsmpl, sizeof(subset_t)); for (i=0; isets[i]; set->nsmpl = 1; set->smpl = (int*) calloc(1, sizeof(*set->smpl)); set->smpl[0] = i; set->fname = create_unique_file_name(args, args->hdr_in->samples[i]); } } else if ( args->samples_fname ) { kstring_t str = {0,0,0}; int nfiles = 0; char **files = hts_readlines(args->samples_fname, &nfiles); if ( !nfiles || !files ) error("Failed to parse %s\n", args->samples_fname); args->nsets = 0; args->sets = (subset_t*) calloc(nfiles, sizeof(subset_t)); for (i=0,j=0; isets[args->nsets]; set->nsmpl = 1; str.l = 0; int escaped = 0; char *ptr = files[i]; while ( *ptr ) { if ( *ptr=='\\' && !escaped ) { escaped = 1; ptr++; continue; } if ( isspace(*ptr) && !escaped ) break; if ( *ptr==',' ) set->nsmpl++; // todo: allow commas in sample names kputc(*ptr, &str); escaped = 0; ptr++; } set->smpl = (int*) calloc(set->nsmpl, sizeof(*set->smpl)); char *beg = str.s; j = 0; while ( *beg ) { char *end = beg; while ( *end && *end!=',' ) end++; char tmp = *end; *end = 0; int idx = bcf_hdr_id2int(args->hdr_in, BCF_DT_SAMPLE, beg); if ( idx>=0 ) set->smpl[j++] = idx; else fprintf(stderr,"Warning: The sample \"%s\" is not present in %s\n", beg,args->fname); if ( !tmp ) break; beg = end + 1; } if ( !j ) continue; while ( *ptr && isspace(*ptr) ) ptr++; j = 0; if ( *ptr ) // optional second column with new sample names { set->rename = (char**) calloc(set->nsmpl, sizeof(*set->rename)); beg = ptr; while ( *beg && !isspace(*beg) ) { ptr = beg; while ( *ptr && *ptr!=',' && !isspace(*ptr) ) ptr++; char tmp = *ptr; *ptr = 0; if ( !strcmp("-",beg) ) { if ( j ) error("Error: cannot combine sample names with \"-\"\n"); *ptr = tmp; break; } set->rename[j++] = strdup(beg); *ptr = tmp; if ( !tmp || isspace(tmp) ) break; beg = ptr + 1; if ( j >= set->nsmpl ) error("Expected the same number of samples in the first and second column: %s\n",files[i]); } if ( j ) set->fname = create_unique_file_name(args, set->rename[0]); else { free(set->rename); set->rename = NULL; } } while ( *ptr && isspace(*ptr) ) ptr++; if ( *ptr ) // optional third column with file name { free(set->fname); set->fname = create_unique_file_name(args, ptr); } if ( !set->fname ) set->fname = create_unique_file_name(args, args->hdr_in->samples[set->smpl[0]]); args->nsets++; } for (i=0; igroups_fname is set { void *fname2set = khash_str2int_init(); kstring_t str = {0,0,0}; int nsamples = 0; char **samples = hts_readlines(args->groups_fname, &nsamples); if ( !nsamples || !samples ) error("Failed to parse %s\n", args->groups_fname); args->nsets = 0; for (i=0; ihdr_in, BCF_DT_SAMPLE, samples[i]); if ( idx < 0 ) { fprintf(stderr,"Warning: The sample \"%s\" is not present in %s\n", samples[i],args->fname); continue; } char *rename = NULL; if ( tmp ) // two columns: new sample name { rename = ptr + 1; while ( *rename && isspace(*rename) ) rename++; if ( !*rename ) rename = NULL; // trailing space else { ptr = rename; while ( *ptr && !isspace(*ptr) ) ptr++; tmp = *ptr; *ptr = 0; if ( !strcmp("-",rename) ) rename = NULL; if ( tmp ) ptr++; } while ( *ptr && isspace(*ptr) ) ptr++; } if ( !*ptr ) // no third column, use sample name as file name ptr = samples[i]; char *beg = ptr; while ( *beg ) { ptr = beg; while ( *ptr && *ptr!=',' ) ptr++; tmp = *ptr; *ptr = 0; if ( khash_str2int_get(fname2set,beg,&iset) == -1 ) { args->nsets++; args->sets = (subset_t*) realloc(args->sets,args->nsets*sizeof(subset_t)); iset = args->nsets - 1; if ( khash_str2int_set(fname2set,strdup(beg),iset) < 0 ) error("Failed to insert the key [%s]\n",beg); memset(args->sets+iset,0,sizeof(*args->sets)); } subset_t *set = &args->sets[iset]; set->nsmpl++; set->smpl = (int*) realloc(set->smpl,set->nsmpl*sizeof(*set->smpl)); set->rename = (char**) realloc(set->rename,set->nsmpl*sizeof(*set->rename)); set->smpl[set->nsmpl-1] = idx; set->rename[set->nsmpl-1] = strdup(rename?rename:samples[i]); if ( !set->fname) set->fname = create_unique_file_name(args, beg); if ( !tmp ) break; beg = ptr + 1; } free(samples[i]); } khash_str2int_destroy_free(fname2set); free(str.s); free(samples); } if ( args->unique_fnames ) khash_str2int_destroy_free(args->unique_fnames); } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->region ) { args->sr->require_index = 1; bcf_sr_set_opt(args->sr,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->sr, args->region, args->region_is_file)<0 ) error("Failed to read the regions: %s\n",args->region); } if ( args->target ) { bcf_sr_set_opt(args->sr,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->sr, args->target, args->target_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->target); } if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr_in = bcf_sr_get_header(args->sr,0); mkdir_p("%s/",args->output_dir); int i,j, nsmpl = bcf_hdr_nsamples(args->hdr_in); if ( !nsmpl ) error("No samples to split: %s\n", args->fname); init_subsets(args); // parse tags int is_info = 0, is_fmt = 0; char *beg = args->keep_tags; while ( beg && *beg ) { if ( !strncasecmp("INFO/",beg,5) ) { is_info = 1; is_fmt = 0; beg += 5; } else if ( !strcasecmp("INFO",beg) ) { args->keep_info = 1; break; } else if ( !strncasecmp("INFO,",beg,5) ) { args->keep_info = 1; beg += 5; continue; } else if ( !strncasecmp("FMT/",beg,4) ) { is_info = 0; is_fmt = 1; beg += 4; } else if ( !strncasecmp("FORMAT/",beg,7) ) { is_info = 0; is_fmt = 1; beg += 7; } else if ( !strcasecmp("FMT",beg) ) { args->keep_fmt = 1; break; } else if ( !strcasecmp("FORMAT",beg) ) { args->keep_fmt = 1; break; } else if ( !strncasecmp("FMT,",beg,4) ) { args->keep_fmt = 1; beg += 4; continue; } else if ( !strncasecmp("FORMAT,",beg,7) ) { args->keep_fmt = 1; beg += 7; continue; } char *end = beg; while ( *end && *end!=',' ) end++; char tmp = *end; *end = 0; int id = bcf_hdr_id2int(args->hdr_in, BCF_DT_ID, beg); beg = tmp ? end + 1 : end; if ( is_info && bcf_hdr_idinfo_exists(args->hdr_in,BCF_HL_INFO,id) ) { if ( id >= args->ninfo_tags ) args->ninfo_tags = id + 1; hts_expand0(uint8_t, args->ninfo_tags, args->minfo_tags, args->info_tags); args->info_tags[id] = 1; } if ( is_fmt && bcf_hdr_idinfo_exists(args->hdr_in,BCF_HL_FMT,id) ) { if ( id >= args->nfmt_tags ) args->nfmt_tags = id + 1; hts_expand0(uint8_t, args->nfmt_tags, args->mfmt_tags, args->fmt_tags); args->fmt_tags[id] = 1; } } if ( !args->keep_info && !args->keep_fmt && !args->ninfo_tags && !args->nfmt_tags ) { args->keep_info = args->keep_fmt = 1; } if ( !args->keep_fmt && !args->nfmt_tags ) args->keep_fmt = 1; bcf_hdr_t *tmp_hdr = bcf_hdr_dup(args->hdr_in); if ( !args->keep_info || args->ninfo_tags || args->nfmt_tags ) { int j; for (j=tmp_hdr->nhrec-1; j>=0; j--) { bcf_hrec_t *hrec = tmp_hdr->hrec[j]; if ( hrec->type!=BCF_HL_INFO && hrec->type!=BCF_HL_FMT ) continue; int k = bcf_hrec_find_key(hrec,"ID"); assert( k>=0 ); // this should always be true for valid VCFs int remove = 0; if ( hrec->type==BCF_HL_INFO && (!args->keep_info || args->ninfo_tags) ) { int id = bcf_hdr_id2int(tmp_hdr, BCF_DT_ID, hrec->vals[k]); if ( !args->keep_info || id >= args->ninfo_tags || !args->info_tags[id] ) remove = 1; } if ( hrec->type==BCF_HL_FMT && args->nfmt_tags ) { int id = bcf_hdr_id2int(tmp_hdr, BCF_DT_ID, hrec->vals[k]); if ( id >= args->nfmt_tags || !args->fmt_tags[id] ) remove = 1; } if ( remove ) { char *str = strdup(hrec->vals[k]); bcf_hdr_remove(tmp_hdr,hrec->type,str); free(str); } } if ( bcf_hdr_sync(tmp_hdr)!=0 ) error("Failed to update the VCF header\n"); } kstring_t str = {0,0,0}; for (i=0; insets; i++) { subset_t *set = &args->sets[i]; str.l = 0; kputs(args->output_dir, &str); if ( str.s[str.l-1] != '/' ) kputc('/', &str); kputs(set->fname, &str); char *suffix = NULL; if ( args->output_type & FT_BCF ) suffix = ".bcf"; else if ( args->output_type & FT_GZ ) suffix = ".vcf.gz"; else suffix = ".vcf"; int len = strlen(set->fname); if ( len >= 4 && !strcasecmp(".bcf",set->fname+len-4) ) suffix = NULL; if ( len >= 4 && !strcasecmp(".vcf",set->fname+len-4) ) suffix = NULL; if ( len >= 7 && !strcasecmp(".vcf.gz",set->fname+len-7) ) suffix = NULL; if ( len >= 8 && !strcasecmp(".vcf.bgz",set->fname+len-8) ) suffix = NULL; if ( suffix ) kputs(suffix, &str); char wmode[8]; set_wmode(wmode,args->output_type,str.s,args->clevel); set->fh = hts_open(str.s, wmode); if ( set->fh == NULL ) error("[%s] Error: cannot write to \"%s\": %s\n", __func__, str.s, strerror(errno)); if ( args->hts_opts ) { hts_opt *opts = NULL; for (j=0; jnhts_opts; j++) if ( hts_opt_add(&opts,args->hts_opts[j]) ) error("Could not set the HTS option \"%s\"\n",args->hts_opts[j]); if ( hts_opt_apply(set->fh,opts) ) error("Could not apply the HTS options\n"); hts_opt_free(opts); } set->hdr = tmp_hdr; // dirty: reuse the same header to lower memory for large datasets bcf_hdr_nsamples(set->hdr) = set->nsmpl; for (j=0; jnsmpl; j++) set->hdr->samples[j] = set->rename ? set->rename[j] : args->hdr_in->samples[set->smpl[j]]; if ( bcf_hdr_write(set->fh, set->hdr)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,str.s); if ( init_index2(set->fh,set->hdr,str.s,&set->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",str.s); if ( args->filter_str ) set->filter = filter_init(set->hdr, args->filter_str); } args->hdr_out = tmp_hdr; free(str.s); } static void destroy_data(args_t *args) { bcf_hdr_destroy(args->hdr_out); free(args->info_tags); free(args->fmt_tags); int i,j; for (i=0; insets; i++) { subset_t *set = &args->sets[i]; if ( args->write_index ) { if ( bcf_idx_save(set->fh)<0 ) { if ( hts_close(set->fh)!=0 ) error("Error: close failed .. %s\n", set->fname); error("Error: cannot write to index %s\n", set->index_fn); } free(set->index_fn); } if ( hts_close(set->fh)!=0 ) error("Error: close failed .. %s\n",set->fname); free(set->fname); free(set->smpl); if ( set->filter ) filter_destroy(set->filter); //bcf_hdr_destroy(set->hdr); if ( set->rename ) { for (j=0; jnsmpl; j++) free(set->rename[j]); free(set->rename); } } for (i=0; inhts_opts; i++) free(args->hts_opts[i]); free(args->hts_opts); free(args->sets); bcf_sr_destroy(args->sr); free(args); } static bcf1_t *rec_set_info(args_t *args, subset_t *set, bcf1_t *rec, bcf1_t *out) { if ( out ) { out->n_sample = set->nsmpl; return out; } out = bcf_init1(); out->rid = rec->rid; out->pos = rec->pos; out->rlen = rec->rlen; out->qual = rec->qual; out->n_allele = rec->n_allele; out->n_sample = set->nsmpl; if ( args->keep_info ) { out->n_info = rec->n_info; out->shared.m = out->shared.l = rec->shared.l; out->shared.s = (char*) malloc(out->shared.l); memcpy(out->shared.s,rec->shared.s,out->shared.l); return out; } // build the BCF record kstring_t tmp = {0,0,0}; char *ptr = rec->shared.s; kputsn_(ptr, rec->unpack_size[0], &tmp); ptr += rec->unpack_size[0]; // ID kputsn_(ptr, rec->unpack_size[1], &tmp); ptr += rec->unpack_size[1]; // REF+ALT kputsn_(ptr, rec->unpack_size[2], &tmp); // FILTER if ( args->ninfo_tags ) { int i; for (i=0; in_info; i++) { bcf_info_t *info = &rec->d.info[i]; int id = info->key; if ( !args->info_tags[id] ) continue; kputsn_(info->vptr - info->vptr_off, info->vptr_len + info->vptr_off, &tmp); out->n_info++; } } out->shared.m = tmp.m; out->shared.s = tmp.s; out->shared.l = tmp.l; out->unpacked = 0; return out; } static bcf1_t *rec_set_format(args_t *args, subset_t *set, bcf1_t *src, bcf1_t *dst) { dst->unpacked &= ~BCF_UN_FMT; dst->n_fmt = 0; kstring_t tmp = dst->indiv; tmp.l = 0; int i,j; for (i=0; in_fmt; i++) { bcf_fmt_t *fmt = &src->d.fmt[i]; int id = fmt->id; if ( !args->keep_fmt && (id>=args->nfmt_tags || !args->fmt_tags[id]) ) continue; bcf_enc_int1(&tmp, id); bcf_enc_size(&tmp, fmt->n, fmt->type); for (j=0; jnsmpl; j++) kputsn_(fmt->p + set->smpl[j]*fmt->size, fmt->size, &tmp); dst->n_fmt++; } dst->indiv = tmp; return dst; } static void process(args_t *args) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); bcf_unpack(rec, BCF_UN_ALL); int i; bcf1_t *out = NULL; for (i=0; insets; i++) { subset_t *set = &args->sets[i]; bcf_hdr_nsamples(set->hdr) = set->nsmpl; // dirty: prevent memory duplication for very large sets out = rec_set_info(args, set, rec, out); rec_set_format(args, set, rec, out); int pass = 1; if ( set->filter ) { pass = filter_test(set->filter, out, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; } if ( !pass ) continue; if ( bcf_write(set->fh, set->hdr, out)!=0 ) error("[%s] Error: failed to write the record\n", __func__); } if ( out ) bcf_destroy(out); } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"hts-opts",required_argument,NULL,1}, {"keep-tags",required_argument,NULL,'k'}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,2}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,3}, {"samples-file",required_argument,NULL,'S'}, {"groups-file",required_argument,NULL,'G'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "vr:R:t:T:o:O:i:e:k:S:G:W::",loptions,NULL)) >= 0) { switch (c) { case 1 : args->hts_opts = hts_readlist(optarg,0,&args->nhts_opts); break; case 'k': args->keep_tags = optarg; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'T': args->target = optarg; args->target_is_file = 1; break; case 't': args->target = optarg; break; case 'R': args->region = optarg; args->region_is_file = 1; break; case 'S': args->samples_fname = optarg; break; case 'G': args->groups_fname = optarg; break; case 'r': args->region = optarg; break; case 'o': args->output_dir = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 2 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 3 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( args->samples_fname && args->groups_fname ) error("Error: only one of the options --groups-file or --samples-file can be given\n"); if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->output_dir ) error("Missing the -o option\n"); if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); init_data(args); while ( bcf_sr_next_line(args->sr) ) process(args); destroy_data(args); return 0; } bcftools-1.21/plugins/tag2tag.c000066400000000000000000000610231467060157400164420ustar00rootroot00000000000000/* plugins/tag2tag.c -- convert between similar tags Copyright (C) 2014-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include "bcftools.h" typedef struct { int type; const char *str, *hdr; } tag_t; enum tag { UNKN, GP, GL, PL, GT, QRQA, QS, XX, LXX, LAA, LPL, LAD, AD }; const tag_t tags[] = { [UNKN] = { .type = 0 , .str = NULL, .hdr = NULL }, [GP] = { .type = BCF_HT_REAL, .str = "GP", .hdr = "##FORMAT=" }, [GL] = { .type = BCF_HT_REAL, .str = "GL", .hdr = "##FORMAT=" }, [PL] = { .type = BCF_HT_INT, .str = "PL", .hdr = "##FORMAT=" }, [GT] = { .type = BCF_HT_STR, .str = "GT", .hdr = "##FORMAT=" }, [QRQA] = { .type = BCF_HT_INT, .str = NULL, .hdr = NULL }, [QS] = { .type = BCF_HT_INT, .str = "QS", .hdr = "##FORMAT=" }, // conversion from/to localized allelles get special treatment [XX] = { .type = 0 , .str = NULL, .hdr = NULL }, [LXX] = { .type = 0 , .str = NULL, .hdr = NULL }, [LAA] = { .type = BCF_HT_INT, .str = "LAA", .hdr = "##FORMAT=" }, [LPL] = { .type = BCF_HT_INT, .str = "LPL", .hdr = "##FORMAT=" }, [LAD] = { .type = BCF_HT_INT, .str = "LAD", .hdr = "##FORMAT=" }, [AD] = { .type = BCF_HT_INT, .str = "AD", .hdr = "##FORMAT=" }, }; const int tags_XX[] = { PL, AD, 0 }; const int tags_LXX[] = { LPL, LAD, LAA, 0 }; typedef struct { enum tag src, dst; int loc_src, loc_dst; // bitmask of localized tags marked for conversion (eg 1<src!=UNKN && args->src!=XX && args->src!=LXX ) error("Multiple modes selected: %s\n",optarg); if ( strncmp("--",optarg,2) ) return -1; if ( !strcasecmp("--LXX-to-XX",optarg) ) { args->src = LXX; args->dst = XX; args->loc_src = (1<loc_dst = (1<src = LXX; args->dst = XX; args->loc_src = (1<loc_dst = (1<src = LXX; args->dst = XX; args->loc_src = (1<loc_dst = (1<src = XX; args->dst = LXX; args->loc_src = (1<loc_dst = (1<src = XX; args->dst = LXX; args->loc_src = (1<loc_dst = (1<src = XX; args->dst = LXX; args->loc_src = (1<loc_dst = (1<src = QRQA; args->dst = QS; } else { char *tmp = optarg+2; if ( !strncasecmp("GL-to-",tmp,6) ) args->src = GL, tmp += 6; else if ( !strncasecmp("PL-to-",tmp,6) ) args->src = PL, tmp += 6; else if ( !strncasecmp("GP-to-",tmp,6) ) args->src = GP, tmp += 6; if ( args->src==UNKN ) error("The conversion is not supported: %s\n",optarg); if ( !strcasecmp("GL",tmp) ) args->dst = GL; else if ( !strcasecmp("PL",tmp) ) args->dst = PL; else if ( !strcasecmp("GP",tmp) ) args->dst = GP; else if ( !strcasecmp("GT",tmp) ) args->dst = GT; if ( args->dst==UNKN || args->src==args->dst ) error("The conversion is not supported: %s\n",optarg); } return 0; } void parse_defaults(args_t *args, char *optarg) { char *tmp, *ptr = optarg; while ( *ptr ) { if ( !strncasecmp("AD:",ptr,3) ) { ptr += 3; args->dflt_AD = strtol(ptr,&tmp,10); if ( *tmp && *tmp!=',' && *tmp!='.' ) error("Could not parse: --defaults %s\n",optarg); if ( *tmp=='.' ) { args->dflt_AD = bcf_int32_missing; tmp++; } if ( *tmp ) tmp++; ptr = tmp; } else if ( !strncasecmp("PL:",ptr,3) ) { ptr += 3; args->dflt_PL = strtol(ptr,&tmp,10); if ( *tmp && *tmp!=',' && *tmp!='.' ) error("Could not parse: --defaults %s\n",optarg); if ( *tmp=='.' ) { args->dflt_PL = bcf_int32_missing; tmp++; } if ( *tmp ) tmp++; ptr = tmp; } } } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { args = (args_t*) calloc(1,sizeof(args_t)); args->in_hdr = in; args->out_hdr = out; args->src = args->dst = UNKN; args->dflt_AD = bcf_int32_missing; args->dflt_PL = bcf_int32_missing; static struct option loptions[] = { {"replace",no_argument,NULL,'r'}, {"threshold",required_argument,NULL,'t'}, {"skip-nalt",required_argument,NULL,'s'}, {"defaults",required_argument,NULL,'d'}, {NULL,0,NULL,0} }; opterr = 0; int c; char *tmp; while ((c = getopt_long(argc, argv, "?hrt:s:d:",loptions,NULL)) >= 0) { switch (c) { case 'r': args->drop_src = 1; break; case 'd': parse_defaults(args,optarg); break; case 's': args->skip_nalt = strtol(optarg,&tmp,10); if ( *tmp || args->skip_nalt<0 ) error("Could not parse: --skip-nalt %s\n", optarg); break; case 't': args->gp_th = strtod(optarg,&tmp); if ( *tmp || args->gp_th<0 || args->gp_th>1 ) error("Expected value between [0-1] for -t, --threshold, got %s\n",optarg); break; case 'h': error("%s", usage()); break; default: if ( optind<=0 || parse_ori2new_option(args,argv[optind-1])<0 ) error("%s", usage()); break; } } if ( args->src==UNKN ) error("%s", usage()); // Check if the source tags are defined in the header int tag_id,i; if ( args->src==QRQA ) { if ( (tag_id=bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,"QR"))<0 || !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,tag_id) ) error("The source tag does not exist: QR\n"); if ( bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id)!=tags[args->src].type ) error("The source tag is of different type than required by the VCF specification\n"); if ( (tag_id=bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,"QA"))<0 || !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,tag_id) ) error("The source tag does not exist: QA\n"); if ( bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id)!=tags[args->src].type ) error("The source tag is of different type than required by the VCF specification\n"); } else if ( args->src==LXX ) { for (i=0; tags_LXX[i]; i++) { int j = tags_LXX[i]; if ( !(args->loc_src & (1<in_hdr,BCF_DT_ID,tags[j].str))<0 || !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,tag_id) ) error("The source tag does not exist: %s\n",tags[j].str); if ( bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id)!=tags[j].type ) error("The source tag %s is of different type than required by the VCF specification (%d vs %d)\n",tags[j].str,bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id),tags[j].type); } } else if ( args->src==XX ) { for (i=0; tags_XX[i]; i++) { int j = tags_XX[i]; if ( !(args->loc_src & (1<in_hdr,BCF_DT_ID,tags[j].str))<0 || !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,tag_id) ) error("The source tag does not exist: %s\n",tags[j].str); if ( bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id)!=tags[j].type ) error("The source tag %s is of different type than required by the VCF specification (%d vs %d)\n",tags[j].str,bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id),tags[j].type); } } else { if ( (tag_id=bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,tags[args->src].str))<0 || !bcf_hdr_idinfo_exists(args->in_hdr,BCF_HL_FMT,tag_id) ) error("The source tag does not exist: %s\n",tags[args->src].str); if ( bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id)!=tags[args->src].type ) error("The source tag %s is of different type than required by the VCF specification (%d vs %d)\n",tags[args->src].str,bcf_hdr_id2type(args->in_hdr,BCF_HL_FMT,tag_id),tags[args->src].type); } // Remove tags from the header if -r, --replace was given. However, do not remove if -s, --skip-nalt was given, // in that case some of the records may retain the tags. if ( args->drop_src ) { if ( args->src==QRQA ) { bcf_hdr_remove(args->out_hdr,BCF_HL_FMT,"QR"); bcf_hdr_remove(args->out_hdr,BCF_HL_FMT,"QA"); } else if ( args->src==LXX ) { for (i=0; tags_LXX[i]; i++) { int j = tags_LXX[i]; if ( args->skip_nalt || !(args->loc_src & (1<out_hdr,BCF_HL_FMT,tags[j].str); } } else if ( args->src==XX ) { for (i=0; tags_XX[i]; i++) { int j = tags_XX[i]; if ( args->skip_nalt || !(args->loc_src & (1<out_hdr,BCF_HL_FMT,tags[j].str); } } else bcf_hdr_remove(args->out_hdr,BCF_HL_FMT,tags[args->src].str); } // Add the new tags to the header if ( tags[args->dst].hdr ) bcf_hdr_append(args->out_hdr,tags[args->dst].hdr); else if ( args->dst==LXX ) { for (i=0; tags_LXX[i]; i++) { int j = tags_LXX[i]; if ( !(args->loc_dst & (1<out_hdr,tags[j].hdr); } } else if ( args->dst==XX ) { for (i=0; tags_XX[i]; i++) { int j = tags_XX[i]; if ( !(args->loc_dst & (1<out_hdr,tags[j].hdr); } } return 0; } bcf1_t *process_LXX(bcf1_t *rec) { if ( args->skip_nalt && rec->n_allele > args->skip_nalt ) return rec; // Use LAA to determine mapping between LPL->PL and LAD->AD indices for each sample int nlaa = bcf_get_format_int32(args->in_hdr,rec,"LAA",&args->iarr,&args->miarr); if ( nlaa <=0 ) return rec; int nals = rec->n_allele; int nsmpl = bcf_hdr_nsamples(args->in_hdr); int i,j,k, nlaa1 = nlaa / nsmpl; int nsrc; int drop_laa = args->loc_src; if ( (args->loc_src & (1<in_hdr,rec,"LAD",&args->iarr2,&args->miarr2))>0 ) { int nsrc1 = nsrc / nsmpl; int ndst1 = nals; if ( hts_resize(int32_t,nsmpl*ndst1,&args->miarr3,&args->iarr3,0)!=0 ) return rec; // too big for (i=0; iiarr + i*nlaa1; int32_t *dst = args->iarr3 + i*ndst1; int32_t *src = args->iarr2 + i*nsrc1; dst[0] = src[0]; for (j=1; jdflt_AD; for (j=1; j=0 && laa[j-1]out_hdr,rec,"AD",args->iarr3,nsmpl*nals)!=0 ) error("Error: Failed to set FORMAT/AD at %s:%"PRIhts_pos"\n",bcf_seqname(args->in_hdr,rec),rec->pos+1); if ( args->drop_src ) { bcf_update_format_int32(args->out_hdr,rec,"LAD",NULL,0); drop_laa &= ~(1<loc_src & (1<in_hdr,rec,"LPL",&args->iarr2,&args->miarr2))>0 ) { // for convenience to keep LAA alleles which don't include 0 hts_expand(int32_t,nlaa1+1,args->miarr4,args->iarr4); int32_t *tmp_laa = args->iarr4; tmp_laa[0] = 0; int nsrc1 = nsrc / nsmpl; int ndst1 = nals*(nals+1)/2; if ( hts_resize(int32_t,nsmpl*ndst1,&args->miarr3,&args->iarr3,0)!=0 ) return rec; // too big for (i=0; iiarr + i*nlaa1; int32_t *dst = args->iarr3 + i*ndst1; int32_t *src = args->iarr2 + i*nsrc1; // assuming the simple case: diploid for (j=0; jdflt_PL; for (j=0; j=0 && tmp_laa[j]out_hdr,rec,"PL",args->iarr3,nsmpl*ndst1); if ( args->drop_src ) { bcf_update_format_int32(args->out_hdr,rec,"LPL",NULL,0); drop_laa &= ~(1<drop_src && drop_laa==1<out_hdr,rec,"LAA",NULL,0); return rec; } bcf1_t *process_XX(bcf1_t *rec) { error("todo: --XX-to-LXX\n"); if ( args->skip_nalt && rec->n_allele < args->skip_nalt ) return rec; return rec; } bcf1_t *process(bcf1_t *rec) { int i,j,n; if ( args->src==LXX ) return process_LXX(rec); if ( args->src==XX ) return process_XX(rec); if ( args->src==QRQA ) { int nals = rec->n_allele; int nsmpl = bcf_hdr_nsamples(args->in_hdr); n = bcf_get_format_int32(args->in_hdr,rec,"QR",&args->iarr,&args->miarr); if ( n<=0 ) return rec; if ( n!=nsmpl ) error("Unexpected number of QR values at %s:%"PRIhts_pos"\n",bcf_seqname(args->in_hdr,rec),rec->pos+1); if ( nals==1 ) bcf_update_format_int32(args->out_hdr,rec,"QS",args->iarr,nsmpl); else { int n2 = bcf_get_format_int32(args->in_hdr,rec,"QA",&args->iarr2,&args->miarr2); if ( n2<=0 ) return rec; if ( n*(nals-1) != n2 ) error("Unexpected number of QR vs QA values at %s:%"PRIhts_pos"\n",bcf_seqname(args->in_hdr,rec),rec->pos+1); hts_expand(int32_t,nsmpl*nals,args->miarr3,args->iarr3); for (i=0; iiarr3[i*nals] = args->iarr[i]; for (j=1; jiarr3[i*nals+j] = args->iarr2[i*(nals-1)+j-1]; } bcf_update_format_int32(args->out_hdr,rec,"QS",args->iarr3,nals*nsmpl); } if ( args->drop_src ) { bcf_update_format_int32(args->out_hdr,rec,"QR",NULL,0); bcf_update_format_int32(args->out_hdr,rec,"QA",NULL,0); } return rec; } // convert source tags to GL. If performance is an issue, can be smarter if ( tags[args->src].type==BCF_HT_REAL ) { // from GL,GP to something n = bcf_get_format_float(args->in_hdr,rec,tags[args->src].str,&args->farr,&args->mfarr); if ( n<=0 ) return rec; // convert to GL if ( args->src==GP ) { for (i=0; ifarr[i]) || bcf_float_is_vector_end(args->farr[i]) ) continue; args->farr[i] = args->farr[i] ? log10(args->farr[i]) : -99; } } } else if ( tags[args->src].type==BCF_HT_INT ) { // from PL to something n = bcf_get_format_int32(args->in_hdr,rec,tags[args->src].str,&args->iarr,&args->miarr); if ( n<=0 ) return rec; hts_expand(float, n, args->mfarr, args->farr); // convert to GL for (i=0; iiarr[i]==bcf_int32_missing ) bcf_float_set_missing(args->farr[i]); else if ( args->iarr[i]==bcf_int32_vector_end ) bcf_float_set_vector_end(args->farr[i]); else args->farr[i] = -0.1 * args->iarr[i]; } } else error("fixme: expected BCF_HT_REAL or BCF_HT_INT for source tag\n"); if ( args->dst==GL ) bcf_update_format_float(args->out_hdr,rec,"GL",args->farr,n); else if ( args->dst==PL ) { hts_expand(int32_t, n, args->miarr, args->iarr); for (i=0; ifarr[i]) ) args->iarr[i] = bcf_int32_missing; else if ( bcf_float_is_vector_end(args->farr[i]) ) args->iarr[i] = bcf_int32_vector_end; else args->iarr[i] = lroundf(-10*args->farr[i]); } bcf_update_format_int32(args->out_hdr,rec,"PL",args->iarr,n); } else if ( args->dst==GP || args->dst==GT ) { int nsmpl = bcf_hdr_nsamples(args->in_hdr); int n1 = n / nsmpl; for (i=0; ifarr + i*n1; float sum = 0; for (j=0; jdst==GP ) bcf_update_format_float(args->out_hdr,rec,"GP",args->farr,n); } if ( args->dst==GT ) { // farr contains GP. If performance is an issue, note that if the src was GP, we made an unnecessary conversion GP->GL->GP int nsmpl = bcf_hdr_nsamples(args->in_hdr); int n1 = n / nsmpl; int nals = rec->n_allele; hts_expand(int32_t,nsmpl*2,args->miarr,args->iarr); for (i=0; ifarr + i*n1; if ( bcf_float_is_missing(ptr[0]) ) { args->iarr[2*i] = args->iarr[2*i+1] = bcf_gt_missing; continue; } int jmax = 0; for (j=1; j ptr[jmax] ) jmax = j; } // haploid genotype if ( j==nals ) { args->iarr[2*i] = ptr[jmax] < 1 - args->gp_th ? bcf_gt_missing : bcf_gt_unphased(jmax); args->iarr[2*i+1] = bcf_int32_vector_end; continue; } if ( j!=nals*(nals+1)/2 ) error("Wrong number of GP values for diploid genotype at %s:%"PRId64", expected %d, found %d\n", bcf_seqname(args->in_hdr,rec), rec->pos+1, nals*(nals+1)/2,j); if ( ptr[jmax] < 1 - args->gp_th ) { args->iarr[2*i] = args->iarr[2*i+1] = bcf_gt_missing; continue; } // most common case: RR if ( jmax==0 ) { args->iarr[2*i] = args->iarr[2*i+1] = bcf_gt_unphased(0); continue; } int a,b; bcf_gt2alleles(jmax,&a,&b); args->iarr[2*i] = bcf_gt_unphased(a); args->iarr[2*i+1] = bcf_gt_unphased(b); } bcf_update_genotypes(args->out_hdr,rec,args->iarr,nsmpl*2); } if ( args->drop_src ) { if ( tags[args->src].type==BCF_HT_REAL ) bcf_update_format_float(args->out_hdr,rec,tags[args->src].str,NULL,0); else if ( tags[args->src].type==BCF_HT_INT ) bcf_update_format_int32(args->out_hdr,rec,tags[args->src].str,NULL,0); } return rec; } void destroy(void) { free(args->farr); free(args->iarr); free(args->iarr2); free(args->iarr3); free(args->iarr4); free(args); } bcftools-1.21/plugins/trio-dnm2.c000066400000000000000000002302771467060157400167350ustar00rootroot00000000000000/* The MIT License Copyright (c) 2018-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include // for isatty #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "regidx.h" #include "filter.h" #define USE_DNG 1 // DeNovoGear model #define USE_ACM 2 // the new "allele-centric model" which combines fixed DNG priors with allele centric approach #define USE_NAIVE 3 // a naive calling model based on observed GT // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define iFATHER 0 // don't modify, QS calculations depend on this order! #define iMOTHER 1 #define iCHILD 2 // output tag type #define DNM_INT (1<<0) #define DNM_FLOAT (1<<1) #define DNM_LOG ((1<<2)|DNM_FLOAT) #define DNM_PHRED ((1<<3)|DNM_INT) #define DNM_PROB ((1<<4)|DNM_FLOAT) #define DNM_FLAG ((1<<5)|DNM_INT) typedef struct { int idx[3]; // VCF sample index for child, father, mother int pass, // do all three pass the filters? is_male; // male pattern of chrX inheritance? } trio_t; typedef struct { // combines priors, mutation rates, genotype transmission probability; see init_priors() double pprob[10][10][10]; // prior probability; the order is father,mother,child uint8_t denovo[10][10][10]; // is the GT combination not compatible with normal inheritance (0) or is de novo (1) uint8_t denovo_allele[10][10][10]; // which of the alleles is de novo for this configuration } priors_t; typedef struct { double abs, frac; double abs1, frac1; // applied only if allele observed in a single parent, but not when observed in both } pnoise_t; typedef struct { int argc, filter_logic, regions_is_file, targets_is_file, output_type, record_cmd_line, clevel; int regions_overlap, targets_overlap; char *filter_str; filter_t *filter; char **argv, *ped_fname, *pfm, *output_fname, *fname, *regions, *targets; htsFile *out_fh; bcf_srs_t *sr; bcf_hdr_t *hdr, *hdr_out; char *chrX_list_str; regidx_t *chrX_idx; trio_t *trio; int has_fmt_ad; int ntrio, mtrio; int32_t *pl,*ad,*qs,*gt, *dnm_qual_int, *dnm_allele, *vaf; // input FMT/PL,AD,QS,GT values, output DNM and VAF float *dnm_qual_float; int mpl, mad, mqs, mgt; double min_score; double *pl3; // normalized PLs converted to probs for iFATHER,iMOTHER,iCHILD double *qs3; // QS converted to probs for iFATHER,iMOTHER,iCHILD int maprob, mpl3, mqs3, midx, *idx, force_ad, use_model; double *alt_tmp; int *alt_idx; int malt_tmp, malt_idx; char *dnm_score_tag, // the argument of --dnm-tag, by default DNM:log *dnm_vaf_tag, *dnm_allele_tag; int dnm_score_type; // given by e.g. --dnm-tag DNM:log double mrate; // --mrate, mutation rate pnoise_t pn_snv, pn_indel; // --pn and --pns for SNVs and indels int with_ppl, with_pad; // --with-pPL or --with-pAD int use_dng_priors; // --dng-priors int need_QS; int strictly_novel; priors_t priors, priors_X, priors_XX; char *index_fn; int write_index; } args_t; const char *about(void) { return "Screen variants for possible de-novo mutations in trios.\n"; } static const char *usage_text(void) { return "\n" "About: Screen variants for possible de-novo mutations in trios\n" "Usage: bcftools +trio-dnm2 [OPTIONS]\n" "Common options:\n" " -e, --exclude EXPR Exclude trios for which the expression is true (one matching sample invalidates a trio)\n" " -i, --include EXPR Include trios for which the expression is true (one failing samples invalidates a trio)\n" " -o, --output FILE Output file name [stdout]\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -r, --regions REG Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -t, --targets REG Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " --no-version Do not append version and command line to the header\n" "\n" "General options:\n" " -m, --min-score NUM Do not add FMT/DNM annotation if the score is smaller than NUM\n" " -p, --pfm [1X:|2X:]P,F,M Sample names of child (the proband), father, mother; \"1X:\" for male pattern of chrX inheritance [2X:]\n" " -P, --ped FILE PED file with the columns: ,proband,father,mother,sex(1:male,2:female)\n" " -X, --chrX LIST List of regions with chrX inheritance pattern or one of the presets: [GRCh37]\n" " GRCh37 .. X:1-60000,chrX:1-60000,X:2699521-154931043,chrX:2699521-154931043\n" " GRCh38 .. X:1-9999,chrX:1-9999,X:2781480-155701381,chrX:2781480-155701381\n" " --dnm-tag TAG[:type] Output tag with DNM quality score and its type [DNM:log]\n" " log .. log-scaled quality (-inf,0; float)\n" " flag .. is a DNM, implies --use-NAIVE (1; int)\n" " phred .. phred quality (0-255; int)\n" " prob .. probability (0-1; float)\n" " --force-AD Calculate VAF even if the number of FMT/AD fields is incorrect. Use at your own risk!\n" " --va TAG Output tag name for the variant allele [VA]\n" " --vaf TAG Output tag name for variant allele fraction [VAF]\n" "\n" "Model options:\n" " --dng-priors Use the original DeNovoGear priors (including bugs in prior assignment, but with chrX bugs fixed)\n" " --mrate NUM Mutation rate [1e-8]\n" " --pn FRAC[,NUM][:type] Tolerance to parental noise or mosaicity, given as fraction of QS or number of reads. The type is\n" " 'snv', 'indel' or 'both' [--pn 0.005,0:snv --pn 0,0:indel]\n" " --pns FRAC[,NUM][:type] Same as --pn but applied for alleles observed in a single parent [--pns 0.045,0:snv --pns 0,0:indel]\n" " -n, --strictly-novel When Mendelian inheritance is violiated, score highly only novel alleles (e.g. in LoH regions)\n" " --use-DNG The original DeNovoGear model, implies --dng-priors\n" " --use-NAIVE A naive calling model which uses only FMT/GT to determine DNMs\n" " --with-pAD Do not use FMT/QS but parental FMT/AD\n" " --with-pPL Do not use FMT/QS but parental FMT/PL. Equals to DNG with bugs fixed (more FPs, fewer FNs)\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "\n" "Example:\n" " # Annotate VCF with FORMAT/DNM, run for a single trio\n" " bcftools +trio-dnm2 -p proband,father,mother file.bcf\n" "\n" " # Same as above, but read the trio(s) from a PED file\n" " bcftools +trio-dnm2 -P file.ped file.bcf\n" "\n" " # Same as above plus extract a list of significant DNMs using the bcftools/query command\n" " bcftools +trio-dnm2 -P file.ped file.bcf -Ou | bcftools query -i'DNM>10' -f'[%CHROM:%POS %SAMPLE %DNM\\n]'\n" "\n" " # A complete example with a variant calling step. Note that this is one long\n" " # command and should be on a single line. Also note that a filtering step is\n" " # recommended, e.g. by depth and VAF (not shown here):\n" " bcftools mpileup -a AD,QS -f ref.fa -Ou proband.bam father.bam mother.bam |\n" " bcftools call -mv -Ou |\n" " bcftools +trio-dnm2 -p proband,father,mother -Oz -o output.vcf.gz\n" "\n"; } static int cmp_trios(const void *_a, const void *_b) { trio_t *a = (trio_t *) _a; trio_t *b = (trio_t *) _b; int i; int amin = a->idx[0]; for (i=1; i<3; i++) if ( amin > a->idx[i] ) amin = a->idx[i]; int bmin = b->idx[0]; for (i=1; i<3; i++) if ( bmin > b->idx[i] ) bmin = b->idx[i]; if ( amin < bmin ) return -1; if ( amin > bmin ) return 1; return 0; } static void parse_ped(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); kstring_t str = {0,0,0}; if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); int moff = 0, *off = NULL; do { // familyID sampleID paternalID maternalID sex phenotype population relationship siblings secondOrder thirdOrder children comment // BB03 HG01884 HG01885 HG01956 2 0 ACB child 0 0 0 0 int ncols = ksplit_core(str.s,0,&moff,&off); if ( ncols<4 ) error("Could not parse the ped file: %s\n", str.s); int father = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[2]]); if ( father<0 ) continue; int mother = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[3]]); if ( mother<0 ) continue; int child = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); if ( child<0 ) continue; int sex = 0; if ( ncols>=5 ) { char *tmp; sex = strtol(&str.s[off[4]],&tmp,10); if ( tmp==&str.s[off[4]] || *tmp ) error("Could not parse the PED file, the 5th column should be numeric: %s\n",str.s); if ( sex!=1 && sex!=2 ) sex = 0; } args->ntrio++; hts_expand0(trio_t,args->ntrio,args->mtrio,args->trio); trio_t *trio = &args->trio[args->ntrio-1]; trio->idx[iFATHER] = father; trio->idx[iMOTHER] = mother; trio->idx[iCHILD] = child; trio->is_male = sex==1 ? 1 : 0; } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); // sort the sample by index so that they are accessed more or less sequentially qsort(args->trio,args->ntrio,sizeof(trio_t),cmp_trios); // check for duplicates int i; for (i=1; intrio; i++) { trio_t *ta = &args->trio[i-1]; trio_t *tb = &args->trio[i]; if ( ta->idx[0]==tb->idx[0] && ta->idx[1]==tb->idx[1] && ta->idx[2]==tb->idx[2] ) error("Error: duplicate trio entries detected in the PED file: %s\n",fname); } fprintf(stderr,"Identified %d complete trio%s in the VCF file\n", args->ntrio,args->ntrio==1?"":"s"); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } static const uint8_t seq1[10] = {0,1,1,2,2,2,3,3,3,3}; static const uint8_t seq2[10] = {0,0,1,0,1,2,0,1,2,3}; static const int8_t seq3[13] = {-1,0,2,1,5,3,4,-1,9,6,7,-1,8}; // Lookup from (1<3 ) // 4 different alleles in the trio gt_prior = 1e-26; else if ( nals_mf>=3 ) // 3 different alleles in parents, gt_prior = 0.002 * 0.002 / 414; // split equally amongst all triallelic cases else if ( nals_mfc==3 ) // 3rd allele in the child gt_prior = 1e-3 * 1e-3; // This is what g_PolyRate evaluates in DNG code else if ( nref_mf==4 ) gt_prior = 0.995 * 0.998; // 4 copies of ref in parents else if ( nref_mf==3 ) gt_prior = 0.995 * 0.002 * (3.0/5.0) * (4.0/5.0) * 0.5; // 3 copies of ref in parents else if ( nref_mf==2 && fa==fb && ma==mb ) gt_prior = 0.995 * 0.002 * (2.0/5.0) * (1.0/5.0) * 0.5; // 2 copies of ref in parents, both homs else if ( nref_mf==2 ) gt_prior = 0.995 * 0.002 * (2.0/5.0) * (2.0/5.0); // 2 copies of ref in parents, both hets else if ( nref_mf==1 ) { assert( nals_mf==2 && nals_mfc==2 ); gt_prior = 0.995 * 0.002 * (2.0/5.0) * (2.0/5.0) * 0.5; // 1 copy of ref in parents } else if ( nref_mf==0 ) { if ( nals_mf==1 ) gt_prior = 0.995 * 0.002 * (3.0/5.0) * (1.0/5.0); // 1 alt allele in the trio else if ( nals_mf==2 ) { assert( ca!=0 && cb!=0 ); gt_prior = 0.002 * 0.002 / 414; // 2 alt alleles and 0 refs in the trio } else error("Fixme: %s:%d\n",__FILE__,__LINE__); } else error("Fixme: %s:%d\n",__FILE__,__LINE__); return gt_prior; } // Parent genotype probability L(GM,GF), with DNG bugs fixed static double init_mf_priors(args_t *args, int fi, int mi) { double gt_prior = 0; // parent genotype probability L(GM,GF) int fa = seq1[fi]; int fb = seq2[fi]; int ma = seq1[mi]; int mb = seq2[mi]; int gts[3]; gts[0] = fi; gts[1] = mi; gts[2] = 0; int nalt_mf = count_unique_alleles(2,gts,only_alts); int nref_mf = (fa==0 ? 1 : 0) + (fb==0 ? 1 : 0) + (ma==0 ? 1 : 0) + (mb==0 ? 1 : 0); const double p_homref = 0.998; // this assumes bi-allelic sites const double p_poly = (1 - p_homref) * (1 - p_homref); // p of this occurring twice for a different allele const double p_nonref = 1 - p_homref - p_poly; if ( nalt_mf>=3 ) // penalize heavily sites with 3 unique ALTs gt_prior = 1e-26; else if ( nalt_mf>=2 ) // 2 unique ALTs, 19*3 = 57 cases gt_prior = p_poly / 57.; else if ( nref_mf==4 ) // 0 ALTs; 00,00 gt_prior = p_homref; else if ( nref_mf==3 ) // this and all remaining have 1 unique ALT allele; 00,0x gt_prior = p_nonref * (4.0/15.0) * (1.0/3.0); else if ( nref_mf==2 && ma==mb ) // hom alt; 00,xx gt_prior = p_nonref * (2.0/15.0) * (1.0/3.0); else if ( nref_mf==2 ) // two hets; 0x,0x gt_prior = p_nonref * (4.0/15.0) * (1.0/3.0); else if ( nref_mf==1 ) // single ref; 0x,xx gt_prior = p_nonref * (4.0/15.0) * (1.0/3.0); else if ( nref_mf==0 ) // no ref; xx,xx gt_prior = p_nonref * (1.0/15.0) * (1.0/3.0); else error("Fixme: %s:%d\n",__FILE__,__LINE__); return gt_prior; } static double init_mf_priors_chrX(args_t *args, int mi) { double gt_prior = 0; // parent genotype probability L(GM) int ma = seq1[mi]; int mb = seq2[mi]; int gts[3]; gts[0] = mi; gts[1] = 0; gts[2] = 0; int nalt_m = count_unique_alleles(1,gts,only_alts); int nref_m = (ma==0 ? 1 : 0) + (mb==0 ? 1 : 0); const double p_homref = 0.999; // this assumes bi-allelic sites const double p_poly = (1 - p_homref) * (1 - p_homref); // p of this occurring twice for a different allele const double p_nonref = 1 - p_homref - p_poly; if ( nalt_m>=2 ) // 2 unique ALTs, 3 cases gt_prior = p_poly / 3.; else if ( nref_m==2 ) // 00 gt_prior = p_homref; else if ( nref_m==1 ) // single ref; 0x and x0 gt_prior = p_nonref * (2.0/3.0) * (1.0/3.0); else if ( nref_m==0 ) // no ref; xx,xx gt_prior = p_nonref * (1.0/3.0) * (1.0/3.0); else error("Fixme: %s:%d\n",__FILE__,__LINE__); return gt_prior; } static double init_mf_priors_chrXX(args_t *args, int fi, int mi) { double gt_prior = 0; // parent genotype probability L(GM) int fa = seq1[fi]; int fb = seq2[fi]; int ma = seq1[mi]; int mb = seq2[mi]; int gts[3]; gts[0] = fi; gts[1] = mi; gts[2] = 0; int nalt_mf = count_unique_alleles(2,gts,only_alts); int nref_mf = (fa==0 ? 1 : 0) + (fb==0 ? 1 : 0) + (ma==0 ? 1 : 0) + (mb==0 ? 1 : 0); if ( fa!=fb ) return 0; // father can't be a het if ( fa==0 ) nref_mf--; else nalt_mf--; const double p_homref = 0.998; // this assumes bi-allelic sites const double p_poly = (1 - p_homref) * (1 - p_homref); // p of this occurring twice for a different allele const double p_nonref = 1 - p_homref - p_poly; if ( nalt_mf>=3 ) // 3 unique ALTs gt_prior = 1e-26; else if ( nalt_mf>=2 ) // 2 unique ALTs gt_prior = p_poly * (1.0/9.0) * (1.0/3.0); else if ( nref_mf==3 ) // 00,0 gt_prior = p_homref; else if ( nref_mf==2 ) // 00,x; 0x,0; x0,0 gt_prior = p_nonref * (3.0/7.0) * (1.0/3.0); else if ( nref_mf==1 ) // 0x,x; x0,x; xx,0 gt_prior = p_nonref * (3.0/7.0) * (1.0/3.0); else if ( nref_mf==0 ) // no ref; xx,x gt_prior = p_nonref * (1.0/7.0) * (1.0/3.0); else error("Fixme: %s:%d\n",__FILE__,__LINE__); return gt_prior; } static void init_DNG_tprob_mprob(args_t *args, int fi, int mi, int ci, double *tprob, double *mprob, int *denovo_allele) { int fa = seq1[fi]; int fb = seq2[fi]; int ma = seq1[mi]; int mb = seq2[mi]; int gts[3]; gts[0] = fi; gts[1] = mi; gts[2] = 0; int ca = seq1[ci]; int cb = seq2[ci]; gts[0] = fi; gts[1] = mi; gts[2] = ci; int nals_mfc = count_unique_alleles(3,gts,include_ref); *tprob = 1; // genotype transmission likelihood L(GC|GM,GF), 0 if not compatible with Mendelian inheritance *mprob = 1 - args->mrate; // probability of mutation *denovo_allele = ca!=fa && ca!=fb && ca!=ma && ca!=mb ? ca : cb; if ( nals_mfc==4 ) *tprob = 0; // 4 unique alleles else if ( nals_mfc==3 ) // 3 alleles { if ( ((ca==fa || ca==fb) && (cb==ma || cb==mb)) || ((cb==fa || cb==fb) && (ca==ma || ca==mb)) ) { if ( ca==cb ) *tprob = 0.25; else if ( fa==fb || ma==mb ) *tprob = 0.5; // one parent is homozygous else *tprob = 0.25; } else { if ( ca!=fa && ca!=fb && ca!=ma && ca!=mb && cb!=fa && cb!=fb && cb!=ma && cb!=mb ) *mprob = args->mrate * args->mrate; // two mutations else *mprob = args->mrate; *tprob = 0; } } else if ( nals_mfc==2 ) // 2 alleles { if ( fa!=fb && ma!=mb ) *tprob = 0.25; // both parents are hets else if ( fa==fb && ma==mb ) // both parents are homs { if ( fa==ma && ca==cb ) *tprob = 0, *mprob = args->mrate * args->mrate; // parents same homs, child a hom, two alleles mutated else if ( fa==ma ) *tprob = 0, *mprob = args->mrate; // parents same homs, child a het, one allele mutated else if ( ca==cb ) *tprob = 0, *mprob = args->mrate; // parents diff homs, child a hom, one allele mutated } else if ( ca==cb && ((fa==fb && fa!=ca) || (ma==mb && ma!=ca)) ) *tprob = 0, *mprob = args->mrate; // child is (wrong) hom and one parent is hom else *tprob = 0.5; } } static void init_tprob_mprob(args_t *args, int fi, int mi, int ci, double *tprob, double *mprob, int *denovo_allele) { int fa = seq1[fi]; int fb = seq2[fi]; int ma = seq1[mi]; int mb = seq2[mi]; int ca = seq1[ci]; int cb = seq2[ci]; *denovo_allele = ca!=fa && ca!=fb && ca!=ma && ca!=mb ? ca : cb; // tprob .. genotype transmission probability L(GC|GM,GF), 0 if not compatible with Mendelian inheritance // mprob .. probability of mutation int is_novel; if ( args->strictly_novel ) { // Consider as DNMs only variants with a novel allele. For example, if heterozygosity is lost and // Mendelian inheritance is violated (11+00=11), don't consider this to be a novel allele // (see trio-dnm.11.vcf) // chr1:10000057 f,m,c 11+00=11 .. LoH region // chr1:10697377 f,m,c 11+11=01 .. usually these are indel ambiguities is_novel = ( (ca!=fa && ca!=fb && ca!=ma && ca!=mb) || (cb!=fa && cb!=fb && cb!=ma && cb!=mb) ) ? 1 : 0; if ( is_novel && *denovo_allele==0 ) is_novel = 0; // never count reference allele as novel } else { is_novel = ( ((ca==fa||ca==fb) && (cb==ma||cb==mb)) || ((ca==ma||ca==mb) && (cb==fa||cb==fb)) ) ? 0 : 1; } if ( !is_novel ) { if ( fa==fb && ma==mb ) *tprob = 1; else if ( fa==fb || ma==mb ) *tprob = 0.5; else *tprob = 0.25; *mprob = 1 - args->mrate; } else { *tprob = 0; if ( (ca==fa||ca==fb) || (ca==ma||ca==mb) || (cb==fa||cb==fb) || (cb==ma||cb==mb) ) *mprob = args->mrate; else *mprob = args->mrate * args->mrate; } } static void init_tprob_mprob_chrX(args_t *args, int mi, int ci, double *tprob, double *mprob, int *denovo_allele) { int ma = seq1[mi]; int mb = seq2[mi]; int ca = seq1[ci]; int cb = seq2[ci]; *denovo_allele = ca!=ma && ca!=mb ? ca : cb; if ( ca!=cb ) // male cannot be heterozygous in X *mprob = 0, *tprob = 0; else if ( ca==ma || ca==mb ) // inherited { if ( ma==mb ) *tprob = 1; else *tprob = 0.5; *mprob = 1 - args->mrate; } else // de novo *mprob = args->mrate, *tprob = 0; } static void init_tprob_mprob_chrXX(args_t *args, int fi, int mi, int ci, double *tprob, double *mprob, int *denovo_allele) { int fa = seq1[fi]; int fb = seq2[fi]; int ma = seq1[mi]; int mb = seq2[mi]; int ca = seq1[ci]; int cb = seq2[ci]; *denovo_allele = ca!=fa && ca!=fb && ca!=ma && ca!=mb ? ca : cb; if ( fa!=fb ) { // this must be a genotype error, father cannot be heterozygous in X; don't flag it as a DNM unless // also autosomal inheritance fails init_tprob_mprob(args,fi,mi,ci,tprob,mprob,denovo_allele); } else if ( (ca==fa && (cb==ma||cb==mb)) || (cb==fa && (ca==ma||ca==mb)) ) { if ( ma==mb ) *tprob = 1; else *tprob = 0.5; *mprob = 1 - args->mrate; } else { *tprob = 0; if ( (ca==fa || (ca==ma||ca==mb)) || (cb==fa || (cb==ma||cb==mb)) ) *mprob = args->mrate, *tprob = 0; else *mprob = args->mrate * args->mrate; } } typedef enum { autosomal, chrX, chrXX } init_priors_t; static void init_priors(args_t *args, priors_t *priors, init_priors_t type) { // Based on the FIGL model from the supplement "Variation in genome-wide mutation rates within and between human families" int fi,mi,ci; for (fi=0; fi<10; fi++) { for (mi=0; mi<10; mi++) { for (ci=0; ci<10; ci++) { double gt_prior; // parent genotype probability L(GM,GF) double tprob; // genotype transmission likelihood L(GC|GM,GF), 0 if not compatible with Mendelian inheritance double mprob; // probability of mutation int allele; // which of the alleles is de novo if ( args->use_dng_priors ) gt_prior = init_DNG_mf_priors(args,fi,mi,ci); else if ( type==autosomal ) gt_prior = init_mf_priors(args,fi,mi); else if ( type==chrX ) gt_prior = init_mf_priors_chrX(args,mi); else if ( type==chrXX ) gt_prior = init_mf_priors_chrXX(args,fi,mi); else error("Can't happen\n"); if ( args->use_dng_priors ) init_DNG_tprob_mprob(args,fi,mi,ci,&tprob,&mprob,&allele); else if ( type==autosomal ) init_tprob_mprob(args,fi,mi,ci,&tprob,&mprob,&allele); else if ( type==chrX ) init_tprob_mprob_chrX(args,mi,ci,&tprob,&mprob,&allele); else if ( type==chrXX ) init_tprob_mprob_chrXX(args,fi,mi,ci,&tprob,&mprob,&allele); else error("Can't happen\n"); priors->denovo_allele[fi][mi][ci] = tprob==0 ? allele : UINT8_MAX; // the latter should never happen, making it fail deliberately priors->denovo[fi][mi][ci] = tprob==0 ? 1 : 0; priors->pprob[fi][mi][ci] = log(gt_prior * mprob * (tprob==0 ? 1 : tprob)); } } } } static void init_data(args_t *args) { if ( !args->dnm_score_tag ) { if ( args->use_model==USE_NAIVE ) args->dnm_score_tag = strdup("DNM:flag"); else args->dnm_score_tag = strdup("DNM:log"); } char *ptr = strchr(args->dnm_score_tag,':'); if ( ptr ) { if ( ptr==args->dnm_score_tag ) error("Error: could not parse --dnm-tag %s\n",ptr); *ptr = 0; if ( !strcasecmp(ptr+1,"log") ) args->dnm_score_type = DNM_LOG; else if ( !strcasecmp(ptr+1,"phred") ) args->dnm_score_type = DNM_PHRED; else if ( !strcasecmp(ptr+1,"prob") ) args->dnm_score_type = DNM_PROB; else if ( !strcasecmp(ptr+1,"flag") ) args->dnm_score_type = DNM_FLAG; else error("Error: the type \"%s\" is not supported\n",ptr+1); } else args->dnm_score_type = DNM_LOG; if ( args->dnm_score_type==DNM_FLAG ) { if ( !args->use_model ) args->use_model = USE_NAIVE; else if ( args->use_model!=USE_NAIVE ) error("The output type FLAG can be used only with --use-NAIVE\n"); } if ( args->use_model==USE_NAIVE ) { if ( !args->dnm_score_type ) args->dnm_score_type = DNM_FLAG; else if ( args->dnm_score_type!=DNM_FLAG ) error("The output type FLAG is required with --use-NAIVE\n"); } if ( !args->use_model ) args->use_model = USE_ACM; args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; bcf_sr_set_opt(args->sr,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets ) { bcf_sr_set_opt(args->sr,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); } if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); int id; if ( args->use_model==USE_NAIVE ) { if ( (id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) error("Error: the tag FORMAT/GT is not present in %s\n", args->fname); } else if ( (id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) error("Error: the tag FORMAT/PL is not present in %s\n", args->fname); args->need_QS = ( args->use_model==USE_ACM && !args->with_ppl && !args->with_pad ) ? 1 : 0; if ( args->need_QS && ((id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "QS"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id)) ) error( "Error:\n" " The FORMAT/QS tag is not present. If you want to proceed anyway, add either `--with-pAD` or\n" " `--with-pPL` option, the latter at the cost of inflated false discovery rate. The QS annotation\n" " can be generated at the mpileup step together with the AD annotation using the command\n" " bcftools mpileup -a AD,QS -f ref.fa file.bam\n"); // Possible future todo: use AD as a proxy for QS? if ( args->use_model!=USE_NAIVE ) { if ( (id=bcf_hdr_id2int(args->hdr, BCF_DT_ID, "AD"))<0 || !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) fprintf(stderr, "Warning: the tag FORMAT/AD is not present in %s, the output tag FORMAT/VAF will not be added\n", args->fname); else args->has_fmt_ad = 1; if ( args->with_pad && !args->has_fmt_ad ) error("Error: no FORMAT/AD is present in %s, cannot run with --with-pAD\n", args->fname); } init_priors(args,&args->priors,autosomal); init_priors(args,&args->priors_X,chrX); init_priors(args,&args->priors_XX,chrXX); args->hdr_out = bcf_hdr_dup(args->hdr); char *type = NULL; if ( args->dnm_score_type==DNM_LOG ) type = "log scaled value (bigger value = bigger confidence)"; if ( args->dnm_score_type==DNM_PHRED ) type = "phred value (bigger value = bigger confidence)"; if ( args->dnm_score_type==DNM_PROB ) type = "probability"; if ( args->dnm_score_type==DNM_FLAG ) type = "1 for Mendelian-incompatible genotypes"; bcf_hdr_printf(args->hdr_out, "##FORMAT=",args->dnm_score_tag,(args->dnm_score_type&DNM_INT)?"Integer":"Float",type); bcf_hdr_printf(args->hdr_out, "##FORMAT=",args->dnm_allele_tag); if ( args->has_fmt_ad ) bcf_hdr_printf(args->hdr_out, "##FORMAT=",args->dnm_vaf_tag); int i, n = 0; char **list; if ( args->pfm ) { args->ntrio = 1; args->trio = (trio_t*) calloc(1,sizeof(trio_t)); list = hts_readlist(args->pfm, 0, &n); if ( n!=3 ) error("Expected three sample names with -t\n"); args->trio[0].idx[iCHILD] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[0]); args->trio[0].idx[iFATHER] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[1]); args->trio[0].idx[iMOTHER] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[2]); if ( args->trio[0].idx[iCHILD] < 0 ) { if ( strlen(list[0])>3 && !strncasecmp(list[0],"1X:",3) ) { args->trio[0].idx[iCHILD] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[0]+3); args->trio[0].is_male = 1; } else if ( strlen(list[0])>3 && !strncasecmp(list[0],"2X:",3) ) args->trio[0].idx[iCHILD] = bcf_hdr_id2int(args->hdr, BCF_DT_SAMPLE, list[0]+3); } for (i=0; itrio[0].idx[i] < 0 ) error("The sample is not present: %s\n", list[i]); free(list[i]); } free(list); } else { parse_ped(args,args->ped_fname); if ( !args->ntrio ) error("No complete trio present\n"); } if ( !args->chrX_list_str || !strcasecmp("GRCh37",args->chrX_list_str) ) args->chrX_list_str = "X:1-60000,chrX:1-60000,X:2699521-154931043,chrX:2699521-154931043"; else if ( !strcasecmp("GRCh38",args->chrX_list_str) ) args->chrX_list_str = "X:1-9999,chrX:1-9999,X:2781480-155701381,chrX:2781480-155701381"; char *rmme = strdup(args->chrX_list_str), *tmp = rmme; while ( *tmp ) { if ( *tmp==',' ) *tmp = '\n'; tmp++; } args->chrX_idx = regidx_init_string(rmme, regidx_parse_reg, NULL, 0, NULL); free(rmme); if ( args->record_cmd_line ) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_trio-dnm2"); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( bcf_hdr_write(args->out_fh, args->hdr_out)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr_out,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); if ( args->dnm_score_type & DNM_FLOAT ) args->dnm_qual_float = (float*) malloc(sizeof(*args->dnm_qual_float)*bcf_hdr_nsamples(args->hdr)); else args->dnm_qual_int = (int32_t*) malloc(sizeof(*args->dnm_qual_int)*bcf_hdr_nsamples(args->hdr)); args->vaf = (int32_t*) malloc(sizeof(*args->vaf)*bcf_hdr_nsamples(args->hdr)); args->dnm_allele = (int32_t*) malloc(sizeof(*args->dnm_allele)*bcf_hdr_nsamples(args->hdr)); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); regidx_destroy(args->chrX_idx); free(args->dnm_score_tag); free(args->dnm_vaf_tag); free(args->dnm_allele_tag); free(args->pl3); free(args->alt_tmp); free(args->alt_idx); free(args->idx); free(args->dnm_qual_int); free(args->dnm_qual_float); free(args->dnm_allele); free(args->vaf); free(args->trio); free(args->gt); free(args->pl); free(args->ad); free(args->qs); free(args->qs3); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); bcf_hdr_destroy(args->hdr_out); bcf_sr_destroy(args->sr); free(args); } static inline double phred2num(double phred) { return pow(10,-0.1*phred); } static inline double log2phred(double num) { return fabs(4.3429 * num); } static inline double phred2log(double phred) { return -phred/4.3429; } #if 0 static inline double subtract_num_log(double a_num, double b_log) { return log(a_num - exp(b_log)); } #endif static inline double subtract_log(double a_log, double b_log) // log(exp(a_log)-exp(b_log)) { return a_log + log(1 - exp(b_log - a_log)); } static inline double sum_log(double a, double b) // log(exp(a)+exp(b)) { if ( a==-HUGE_VAL && b==-HUGE_VAL ) return -HUGE_VAL; if ( a>b ) return log(1 + exp(b-a)) + a; else return log(1 + exp(a-b)) + b; } static double process_trio_ACM(args_t *args, priors_t *priors, int nals, double *pl[3], int npl, double *qs[3], int *al0, int *al1) { assert( nals>1 && nals<=4 ); *al0 = *al1 = 0; double sum = -HUGE_VAL, max = -HUGE_VAL; int i, ca,cb, fa,fb, ma,mb, ci=0; for (ca=0; cawith_ppl ) fpl = pl[iFATHER][fi]; else { fpl = 0; for (i=0; i strong genotype fa|fb if ( fals&(1< weaker genotype fa|fb else if ( cals&(1<with_ppl ) mpl = pl[iMOTHER][mi]; else { mpl = 0; for (i=0; ipprob[fi][mi][ci]; // L_{p,f,m} sum = sum_log(sum,val); // this is the denominator, adding to \sum L_{p,f,m} #define DEBUG 0 #if DEBUG if(val!=-HUGE_VAL) fprintf(stderr,"m,f,c: %d%d+%d%d=%d%d dn=%d (%d,%d,%d) mpl,fpl,cpl: %+e %+e %+e \t prior:%+e \t pval=%+e sum=%+e %c\n", mb,ma,fb,fa,cb,ca,priors->denovo[fi][mi][ci],fi,mi,ci,mpl,fpl,cpl,priors->pprob[fi][mi][ci], val,sum,(priors->denovo[fi][mi][ci] && max < val)?'*':'-'); #endif // Is this a valid de novo combination of p,f,m genotypes (ie not inherited), and is it most likely thus far? if ( priors->denovo[fi][mi][ci] && max < val ) { max = val; if ( priors->denovo_allele[fi][mi][ci] == ca ) *al0 = cb, *al1 = ca; else *al0 = ca, *al1 = cb; } mi++; } } fi++; } } ci++; } } #if DEBUG fprintf(stderr,"max=%e sum=%e ret=%e\n",max,sum,max-sum); #endif if ( args->strictly_novel ) { // Downplay de novo calls with alleles present in the parents int ial = *al1; sum = sum_log(sum,qs[iMOTHER][ial] + qs[iFATHER][ial]); max += qs[iMOTHER][ial] + qs[iFATHER][ial]; } // This is the log( 1 - (\max L_pfm) / (\sum L_pfm) ). The default output (DNM:log) prints the inverse. Note log // values smaller than ~40 will be output as -inf due to a loss of precision. That's OK, we are interested // in values very close to 0, bigger than, say, -8 return log2phred(subtract_log(0,max-sum)); } static double process_trio_DNG(args_t *args, priors_t *priors, int nals, double *pl[3], int npl, int *al0, int *al1) { assert( nals>1 && nals<=4 ); *al0 = *al1 = 0; double sum = -HUGE_VAL, max = -HUGE_VAL; int ca,cb, fa,fb, ma,mb, ci=0; for (ca=0; capprob[fi][mi][ci]; sum = sum_log(val,sum); #if DEBUG if(val!=-HUGE_VAL) fprintf(stderr,"m,f,c: %d%d+%d%d=%d%d dn=%d (%d,%d,%d) mpl,fpl,cpl: %+e %+e %+e \t prior:%+e \t pval=%+e sum=%+e %c\n", mb,ma,fb,fa,cb,ca,priors->denovo[fi][mi][ci],fi,mi,ci,pl[iMOTHER][mi],pl[iFATHER][fi],pl[iCHILD][ci],priors->pprob[fi][mi][ci], val,sum,(priors->denovo[fi][mi][ci] && max < val)?'*':'-'); #endif if ( priors->denovo[fi][mi][ci] && max < val ) { max = val; if ( priors->denovo_allele[fi][mi][ci] == ca ) *al0 = cb, *al1 = ca; else *al0 = ca, *al1 = cb; } mi++; } } fi++; } } ci++; } } #if DEBUG fprintf(stderr,"max=%e sum=%e ret=%e\n",max,sum,max-sum); #endif return log2phred(subtract_log(0,max-sum)); } static int process_trio_naive(args_t *args, priors_t *priors, int nals, int32_t gts[3], int *denovo_allele) { int fi = seq3[gts[iFATHER]]; int mi = seq3[gts[iMOTHER]]; int ci = seq3[gts[iCHILD]]; assert( fi!=-1 && mi!=-1 && ci!=-1 ); *denovo_allele = priors->denovo_allele[fi][mi][ci]; return priors->denovo[fi][mi][ci]; } static int test_filters(args_t *args, bcf1_t *rec) { uint8_t *smpl_pass; int i,j, pass_site = filter_test(args->filter, rec, (const uint8_t**) &smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return 0; // no samples, -e mode, the expression failed pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( smpl_pass[idx] ) { pass_trio = 0; break; } // with -e one sample passes, the whole trio fails } args->trio[i].pass = pass_trio; if ( pass_trio ) pass_site = 1; } return pass_site; } for (i=0; intrio; i++) args->trio[i].pass = 1; return 1; } if ( !pass_site ) return 0; if ( smpl_pass ) { pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( !smpl_pass[idx] ) { pass_trio = 0; break; } } args->trio[i].pass = pass_trio; if ( pass_trio ) pass_site = 1; } return pass_site; } for (i=0; intrio; i++) args->trio[i].pass = 1; return 1; } static void many_alts_trim(args_t *args, int *_nals, double *pl[3], int *_npl, double *qs[3]) { assert(*_nals > 4); // Find the most likely set of alleles from FORMAT/QS int nals = *_nals; hts_expand(int,nals,args->malt_idx,args->alt_idx); hts_expand(double,nals,args->malt_tmp,args->alt_tmp); hts_expand(double,10,args->malt_tmp,args->alt_tmp); memset(args->alt_tmp,0,sizeof(*args->alt_tmp)*nals); int i,j,k; for (i=0; i<3; i++) for (j=0; jalt_tmp[j] += qs[i][j]; // sort in ascending order, make REF allele always come first; insertion sort double *arr = args->alt_tmp; int tmp, *idx = args->alt_idx; for (i=0; i1 && arr[idx[j]] < arr[idx[j-1]]; j--) tmp = idx[j], idx[j] = idx[j-1], idx[j-1] = tmp; for (i=0; i<3; i++) { for (j=0; j<4; j++) args->alt_tmp[j] = qs[i][args->alt_idx[j]]; memcpy(qs[i],args->alt_tmp,4*sizeof(*args->alt_tmp)); } for (i=0; i<3; i++) { for (j=0; j<4; j++) for (k=0; k<=j; k++) { int idst = bcf_alleles2gt(j,k); int isrc = bcf_alleles2gt(args->alt_idx[j],args->alt_idx[k]); args->alt_tmp[idst] = pl[i][isrc]; } memcpy(pl[i],args->alt_tmp,10*sizeof(*args->alt_tmp)); } *_nals = 4; *_npl = 10; } static void many_alts_translate(args_t *args, int *al0, int *al1) { *al0 = args->alt_idx[*al0]; *al1 = args->alt_idx[*al1]; } static void set_trio_PL(args_t *args, trio_t *trio, double *ppl[3], int npl1) { int j,k; for (j=0; j<3; j++) // j loops over iFATHER,iMOTHER,iCHILD { int32_t *src = args->pl + npl1 * trio->idx[j]; double *dst = ppl[j] = args->pl3 + j*npl1; double sum = 0; for (k=0; kqs + nqs1 * trio->idx[j]; double *dst = pqs[j] = args->qs3 + j*nqs1; for (k=0; kabs && !pnoise->abs1 && !pnoise->frac1 ) n_ad = 0; // AD is not required if ( n_ad ) { // Noise tolerance will be applied only for alleles observed in a single parent (a possible mosaic // variant in the parent) but not for alleles observed in both parents (likely an artefact) ad_f = args->ad + n_ad * trio->idx[iFATHER]; ad_m = args->ad + n_ad * trio->idx[iMOTHER]; } int j,k; for (j=0; j<3; j++) { int32_t *ad = n_ad ? args->ad + n_ad * trio->idx[j] : NULL; int32_t *qs = args->qs + nqs1 * trio->idx[j]; pqs[j] = args->qs3 + j*nqs1; double pn = 0, pns = 0; double sum_qs = 0, sum_ad = 0; if ( (pnoise->frac || pnoise->frac1) && j!=iCHILD ) { for (k=0; kfrac; pns = sum_qs * pnoise->frac1; if ( n_ad ) { // "absolute" threshold: find the average QS per read from AD and use that // if bigger than the relative threshold for (k=0; kabs * sum_qs / sum_ad ) pn = pnoise->abs * sum_qs / sum_ad; if ( pns < pnoise->abs1 * sum_qs / sum_ad ) pns = pnoise->abs1 * sum_qs / sum_ad; } } // Reduce QS for all alleles to account for noise for (k=0; kpnoise_strict || !ad_f[k] || !ad_m[k] ) val -= noise_tolerance; if ( val < 0 ) val = 0; if ( val > 255 ) val = 255; pqs[j][k] = phred2log(val); } #endif #if 0 // None of this worked better double max_qs = 0; for (k=0; kgt + ngts * trio->idx[j]; for (k=0; k0 && gts[j]<13); } if ( !gts[j] && (j!=iFATHER || !ignore_father) ) return -1; } return 0; } static int set_trio_GT_many_alts(args_t *args, trio_t *trio, int32_t gts[3], int ngts, int nals, int ignore_father) { int i,j,k, nused = 0; hts_expand(int,nals,args->malt_idx,args->alt_idx); for (i=0; ialt_idx[i] = -1; for (j=0; j<3; j++) // iFATHER,iMOTHER,iCHILD { int32_t *src = args->gt + ngts * trio->idx[j]; for (k=0; k= nals ) error("Error: FMT/GT contains incorrect allele \"%d\" at a site with %d alleles\n",ial,nals); if ( args->alt_idx[ial]==-1 ) { args->alt_idx[ial] = nused++; if ( nused > 4 ) return -1; } gts[j] |= 1<alt_idx[ial]; assert(gts[j]>0 && gts[j]<13); } if ( !gts[j] ) return -1; } return 0; } static void process_record_naive(args_t *args, bcf1_t *rec) { int nsmpl = bcf_hdr_nsamples(args->hdr); int ngts = bcf_get_genotypes(args->hdr,rec,&args->gt,&args->mgt); if ( ngts<=0 || ngts==nsmpl ) { if ( bcf_write(args->out_fh, args->hdr_out, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); return; } ngts /= nsmpl; if ( ngts!=2 ) error("todo: ploidy>2\n"); int is_chrX = 0; if ( regidx_overlap(args->chrX_idx,bcf_seqname(args->hdr,rec),rec->pos,rec->pos+rec->rlen,NULL) ) is_chrX = 1; int i, write_dnm = 0; for (i=0; idnm_qual_int[i] = bcf_int32_missing; for (i=0; idnm_allele[i] = bcf_int32_missing; for (i=0; intrio; i++) { if ( args->filter && !args->trio[i].pass ) continue; int ignore_father = 0; // father is irrelevant for male proband on chrX and can have missing GT priors_t *priors; if ( !is_chrX ) priors = &args->priors; else if ( args->trio[i].is_male ) priors = &args->priors_X, ignore_father = 1; else priors = &args->priors_XX; int32_t gts[3] = {0,0,0}; int ret = rec->n_allele<=4 ? set_trio_GT(args,&args->trio[i],gts,ngts,ignore_father) : set_trio_GT_many_alts(args,&args->trio[i],gts,ngts,rec->n_allele,ignore_father); if ( ret<0 ) continue; int dnm_allele; double is_dnm = process_trio_naive(args, priors, rec->n_allele, gts, &dnm_allele); args->dnm_qual_int[ args->trio[i].idx[iCHILD] ] = is_dnm; args->dnm_allele[ args->trio[i].idx[iCHILD] ] = dnm_allele; if ( is_dnm ) write_dnm = 1; } if ( write_dnm ) { int ret = bcf_update_format_int32(args->hdr_out,rec,args->dnm_score_tag,args->dnm_qual_int,nsmpl); if ( ret ) error("Failed to write FORMAT/%s at %s:%"PRId64"\n", args->dnm_score_tag, bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); ret = bcf_update_format_int32(args->hdr_out,rec,args->dnm_allele_tag,args->dnm_allele,nsmpl); if ( ret ) error("Failed to write FORMAT/%s at %s:%"PRId64"\n", args->dnm_allele_tag,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); } if ( bcf_write(args->out_fh, args->hdr_out, rec)!=0 ) error("[%s] Error: cannot write to %s at %s:%"PRId64"\n", __func__,args->output_fname,bcf_seqname(args->hdr,rec),(int64_t)rec->pos+1); } static void process_record(args_t *args, bcf1_t *rec) { int skip_site = 0; if ( rec->n_allele==1 || bcf_get_variant_types(rec)==VCF_REF ) skip_site = 1; else if ( args->filter && !test_filters(args,rec) ) skip_site = 1; if ( skip_site ) { if ( bcf_write(args->out_fh, args->hdr_out, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); return; } if ( args->use_model==USE_NAIVE ) { process_record_naive(args, rec); return; } static int n_ad_warned = 0; int nret, nsmpl = bcf_hdr_nsamples(args->hdr), n_ad = args->has_fmt_ad; if ( n_ad ) { nret = bcf_get_format_int32(args->hdr,rec,"AD",&args->ad,&args->mad); if ( nret<=0 ) n_ad = 0; else { n_ad = nret / nsmpl; if ( nret != nsmpl * rec->n_allele ) { if ( !n_ad_warned ) { hts_log_warning("Incorrect number of fields for FORMAT/AD at %s:%"PRId64". This warning is printed only once", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); n_ad_warned = 1; } if ( !args->force_ad ) n_ad = 0; } } } nret = bcf_get_format_int32(args->hdr,rec,"PL",&args->pl,&args->mpl); if ( nret<=0 ) error("The FORMAT/PL tag not present at %s:%"PRId64"\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); int npl1 = nret/nsmpl; if ( npl1!=rec->n_allele*(rec->n_allele+1)/2 ) error("todo: not a diploid site at %s:%"PRId64": %d alleles, %d PLs\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,rec->n_allele,npl1); hts_expand(double,3*npl1,args->mpl3,args->pl3); int i,j, nqs1 = 0; if ( args->use_model==USE_ACM || rec->n_allele > 4 ) // DNG does not use QS, but QS is needed when trimming ALTs { nret = bcf_get_format_int32(args->hdr,rec,"QS",&args->qs,&args->mqs); if ( nret<0 ) { if ( args->need_QS ) error("Error: the FMT/QS tag is not available at %s:%"PRId64".\n",bcf_seqname(args->hdr,rec),(int64_t)rec->pos+1); if ( n_ad==0 ) { static int missing_AD_warned = 0; if ( !missing_AD_warned ) { hts_log_warning( "Neither FMT/QS nor FMT/AD present at %s:%"PRId64", cannot trim the number of alleles to four, skipping.\n" "This warning is printed only once", bcf_seqname(args->hdr,rec),(int64_t)rec->pos+1); missing_AD_warned = 1; } return; } // fake QS from AD assuming average BQ=30, used by --with-pAD nret = n_ad * nsmpl; hts_expand(int32_t,nret,args->mqs,args->qs); for (i=0; iad[i]==bcf_int32_missing || args->ad[i]==bcf_int32_vector_end ) args->qs[i] = args->ad[i]; else args->qs[i] = 30 * args->ad[i]; } } else if ( nret != nsmpl * rec->n_allele ) error("Error: incorrect number of FMT/QS values at %s:%"PRId64".\n",bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); nqs1 = nret<=0 ? 0 : nret/nsmpl; hts_expand(double,3*nqs1,args->mqs3,args->qs3); } pnoise_t *pnoise = (bcf_get_variant_types(rec) & VCF_INDEL) ? &args->pn_indel : &args->pn_snv; int is_chrX = 0; if ( regidx_overlap(args->chrX_idx,bcf_seqname(args->hdr,rec),rec->pos,rec->pos+rec->rlen,NULL) ) is_chrX = 1; int al0, al1, write_dnm = 0, ad_set = 0; if ( args->dnm_score_type & DNM_FLOAT ) for (i=0; idnm_qual_float[i]); else for (i=0; idnm_qual_int[i] = bcf_int32_missing; for (i=0; idnm_allele[i] = bcf_int32_missing; for (i=0; ivaf[i] = bcf_int32_missing; for (i=0; intrio; i++) { if ( args->filter && !args->trio[i].pass ) continue; // Samples can be in any order in the VCF, set PL and QS to reflect the iFATHER,iMOTHER,iCHILD indices double *ppl[3]; set_trio_PL(args,&args->trio[i],ppl,npl1); double *pqs[3]; if ( args->use_model==USE_ACM ) set_trio_QS_noisy(args,&args->trio[i],pqs,nqs1,n_ad,pnoise); else if ( rec->n_allele > 4 ) // DNG does not use QS, but QS is needed when trimming ALTs set_trio_QS(args,&args->trio[i],pqs,nqs1); priors_t *priors; if ( !is_chrX ) priors = &args->priors; else if ( args->trio[i].is_male ) priors = &args->priors_X; else priors = &args->priors_XX; int nals = rec->n_allele; if ( rec->n_allele > 4 ) many_alts_trim(args, &nals,ppl,&npl1,pqs); double score; if ( args->use_model==USE_ACM ) score = process_trio_ACM(args, priors, nals, ppl, npl1, pqs, &al0, &al1); else if ( args->use_model==USE_DNG ) score = process_trio_DNG(args, priors, nals, ppl, npl1, &al0, &al1); else error("Uh, this should not happen\n"); if ( rec->n_allele > 4 ) many_alts_translate(args, &al0, &al1); if ( score >= args->min_score ) { write_dnm = 1; if ( args->dnm_score_type==DNM_LOG ) args->dnm_qual_float[ args->trio[i].idx[iCHILD] ] = score==HUGE_VAL ? 0 : subtract_log(0,phred2log(score)); else if ( args->dnm_score_type==DNM_PROB ) args->dnm_qual_float[ args->trio[i].idx[iCHILD] ] = score==HUGE_VAL ? 1 : 1 - phred2num(score); else { if ( score>255 ) score = 255; args->dnm_qual_int[ args->trio[i].idx[iCHILD] ] = round(score); } args->dnm_allele[ args->trio[i].idx[iCHILD] ] = al1; } if ( n_ad ) { if ( al1 < n_ad ) { ad_set = 1; for (j=0; j<3; j++) { int32_t *src = args->ad + n_ad * args->trio[i].idx[j]; int k, ad_sum = 0; for (k=0; kn_allele; k++) ad_sum += src[k]; args->vaf[ args->trio[i].idx[j] ] = ad_sum ? round(src[al1]*100./ad_sum) : 0; } } else for (j=0; j<3; j++) args->vaf[ args->trio[i].idx[j] ] = bcf_int32_missing; } } if ( write_dnm ) { int ret; if ( args->dnm_score_type & DNM_FLOAT ) ret = bcf_update_format_float(args->hdr_out,rec,args->dnm_score_tag,args->dnm_qual_float,nsmpl); else ret = bcf_update_format_int32(args->hdr_out,rec,args->dnm_score_tag,args->dnm_qual_int,nsmpl); if ( ret ) error("Failed to write FORMAT/%s at %s:%"PRId64"\n", args->dnm_score_tag, bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); ret = bcf_update_format_int32(args->hdr_out,rec,args->dnm_allele_tag,args->dnm_allele,nsmpl); if ( ret ) error("Failed to write FORMAT/%s at %s:%"PRId64"\n", args->dnm_allele_tag,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); if ( ad_set ) { if ( bcf_update_format_int32(args->hdr_out,rec,args->dnm_vaf_tag,args->vaf,nsmpl)!=0 ) error("Failed to write FORMAT/%s at %s:%"PRId64"\n", args->dnm_vaf_tag,bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1); } } if ( bcf_write(args->out_fh, args->hdr_out, rec)!=0 ) error("[%s] Error: cannot write to %s at %s:%"PRId64"\n", __func__,args->output_fname,bcf_seqname(args->hdr,rec),(int64_t)rec->pos+1); } static void set_option(args_t *args, char *optarg) { static int warn_deprecated = 1; if ( warn_deprecated ) { fprintf(stderr,"Note: the `-u, --use` option will be deprecated in future releases.\n"); warn_deprecated = 0; } char *tmp; char *opt = strdup(optarg); char *val = strchr(opt,'='); if ( val ) { *val = 0; val++; } if ( !strcasecmp(opt,"mrate") ) { if ( !val ) error("Error: expected value with -u mrate, e.g. -u mrate=1e-8\n"); args->mrate = strtod(val,&tmp); if ( *tmp ) error("Could not parse: -u %s\n", optarg); } else if ( !strcasecmp(opt,"pn") || !strcasecmp(opt,"pnoise") ) { if ( !val ) error("Error: expected value with -u %s, e.g. -u %s=0.05\n",opt,opt); double pn_frac,pn_abs = 0; pn_frac = strtod(val,&tmp); if ( *tmp && *tmp==',' ) { pn_abs = strtod(tmp+1,&tmp); if ( *tmp ) error("Could not parse: -u %s\n", optarg); } if ( pn_frac<0 || pn_frac>1 ) error("Error: expected value from the interval [0,1] for -u %s\n", optarg); if ( pn_abs<0 ) error("Error: expected positive value for -u %s\n", optarg); args->pn_snv.frac = pn_frac; args->pn_snv.abs = pn_abs; args->pn_indel = args->pn_snv; } else if ( !strcasecmp(opt,"pns") ) { if ( !val ) error("Error: expected value with -u %s, e.g. -u %s=0.05\n",opt,opt); double pn_frac,pn_abs = 0; pn_frac = strtod(val,&tmp); if ( *tmp && *tmp==',' ) { pn_abs = strtod(tmp+1,&tmp); if ( *tmp ) error("Could not parse: -u %s\n", optarg); } if ( pn_frac<0 || pn_frac>1 ) error("Error: expected value from the interval [0,1] for -u %s\n", optarg); if ( pn_abs<0 ) error("Error: expected positive value for -u %s\n", optarg); args->pn_snv.frac1 = pn_frac; args->pn_snv.abs1 = pn_abs; args->pn_indel = args->pn_snv; } else if ( !strcasecmp(opt,"DNG") ) { args->use_model = USE_DNG; args->use_dng_priors = 1; } else if ( !strcasecmp(opt,"dng-priors") ) args->use_dng_priors = 1; else if ( !strcasecmp(opt,"ppl") ) args->with_ppl = 1; else if ( !strcasecmp(opt,"tag") ) { if ( !val ) error("Error: expected value with -u tag, e.g. -u tag=ANN\n"); free(args->dnm_score_tag); args->dnm_score_tag = strdup(val); } else if ( !strcasecmp(opt,"vaf") ) { if ( !val ) error("Error: expected value with -u vaf, e.g. -u vaf=VAF\n"); free(args->dnm_vaf_tag); args->dnm_vaf_tag = strdup(val); } else if ( !strcasecmp(opt,"va") ) { if ( !val ) error("Error: expected value with -u va, e.g. -u va=VA\n"); free(args->dnm_allele_tag); args->dnm_allele_tag = strdup(val); } else error("Error: the option \"-u %s\" is not recognised\n",optarg); free(opt); } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->dnm_vaf_tag = strdup("VAF"); args->dnm_allele_tag = strdup("VA"); args->mrate = 1e-8; args->pn_snv.frac = 0.005; args->pn_snv.frac1 = 0.045; args->pn_snv.abs = 0; args->pn_snv.abs1 = 0; args->record_cmd_line = 1; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"use",required_argument,0,'u'}, {"force-AD",no_argument,0,1}, {"dnm-tag",required_argument,0,2}, {"va",required_argument,0,3}, {"vaf",required_argument,0,4}, {"dng-priors",no_argument,0,5}, {"mrate",required_argument,0,6}, {"pn",required_argument,0,7}, {"pns",required_argument,0,8}, {"use-DNG",no_argument,0,9}, {"ppl",no_argument,0,10}, {"with-pPL",no_argument,0,10}, {"with-ppl",no_argument,0,10}, {"use-NAIVE",no_argument,0,11}, {"no-version",no_argument,NULL,12}, {"with-pAD",no_argument,0,13}, {"with-pad",no_argument,0,13}, {"chrX",required_argument,0,'X'}, {"min-score",required_argument,0,'m'}, {"strictly-novel",no_argument,0,'n'}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"ped",required_argument,NULL,'P'}, {"pfm",required_argument,NULL,'p'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,14}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,15}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; double pn_abs, pn_frac; while ((c = getopt_long(argc, argv, "p:P:o:O:s:i:e:r:R:t:T:m:au:X:nW::",loptions,NULL)) >= 0) { switch (c) { case 1 : args->force_ad = 1; break; case 2 : free(args->dnm_score_tag); args->dnm_score_tag = strdup(optarg); break; case 3 : free(args->dnm_allele_tag); args->dnm_allele_tag = strdup(optarg); break; case 4 : free(args->dnm_vaf_tag); args->dnm_vaf_tag = strdup(optarg); break; case 5 : args->use_dng_priors = 1; break; case 6 : args->mrate = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --mrate %s\n", optarg); break; case 7 : pn_frac = strtod(optarg,&tmp); pn_abs = 0; if ( *tmp && *tmp==',' ) { pn_abs = strtod(tmp+1,&tmp); if ( *tmp ) { if ( *tmp!=':' ) error("Could not parse: --pn %s\n", optarg); if ( !strcasecmp("snv",tmp+1) ) { args->pn_snv.frac = pn_frac; args->pn_snv.abs = pn_abs; } else if ( !strcasecmp("indel",tmp+1) ) { args->pn_indel.frac = pn_frac; args->pn_indel.abs = pn_abs; } else error("Could not parse: --pn %s\n", optarg); } else { args->pn_snv.frac = pn_frac; args->pn_snv.abs = pn_abs; args->pn_indel.frac = pn_frac; args->pn_indel.abs = pn_abs; } } else if ( *tmp ) error("Could not parse: --pn %s\n", optarg); else { args->pn_snv.frac = pn_frac; args->pn_indel.frac = pn_frac; } if ( pn_frac<0 || pn_frac>1 ) error("Error: expected value from the interval [0,1] for --pn %s\n", optarg); if ( pn_abs<0 ) error("Error: expected positive value for --pn %s\n", optarg); break; case 8 : pn_frac = strtod(optarg,&tmp); pn_abs = 0; if ( *tmp && *tmp==',' ) { pn_abs = strtod(tmp+1,&tmp); if ( *tmp ) { if ( *tmp!=':' ) error("Could not parse: --pns %s\n", optarg); if ( !strcasecmp("snv",tmp+1) ) { args->pn_snv.frac1 = pn_frac; args->pn_snv.abs1 = pn_abs; } else if ( !strcasecmp("indel",tmp+1) ) { args->pn_indel.frac1 = pn_frac; args->pn_indel.abs1 = pn_abs; } else error("Could not parse: --pns %s\n", optarg); } else { args->pn_snv.frac1 = pn_frac; args->pn_snv.abs1 = pn_abs; args->pn_indel.frac1 = pn_frac; args->pn_indel.abs1 = pn_abs; } } else if ( *tmp ) error("Could not parse: --pns %s\n", optarg); else { args->pn_snv.frac1 = pn_frac; args->pn_indel.frac1 = pn_frac; } if ( pn_frac<0 || pn_frac>1 ) error("Error: expected value from the interval [0,1] for --pns %s\n", optarg); if ( pn_abs<0 ) error("Error: expected positive value for --pns %s\n", optarg); break; case 9 : args->use_model = USE_DNG; args->use_dng_priors = 1; break; case 10 : args->with_ppl = 1; break; case 11 : args->use_model = USE_NAIVE; break; case 12 : args->record_cmd_line = 0; break; case 13 : args->with_pad = 1; break; case 14 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 15 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'X': args->chrX_list_str = optarg; break; case 'u': set_option(args,optarg); break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'P': args->ped_fname = optarg; break; case 'p': args->pfm = optarg; break; case 'm': args->min_score = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -M, --min-score %s\n", optarg); break; case 'n': args->strictly_novel = 1; break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->ped_fname && !args->pfm ) error("Missing the -p or -P option\n"); if ( args->ped_fname && args->pfm ) error("Expected only -p or -P option, not both\n"); init_data(args); while ( bcf_sr_next_line(args->sr) ) process_record(args, bcf_sr_get_line(args->sr,0)); destroy_data(args); return 0; } bcftools-1.21/plugins/trio-stats.c000066400000000000000000000767361467060157400172430ustar00rootroot00000000000000/* The MIT License Copyright (c) 2018-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include // for isatty #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define iCHILD 0 #define iFATHER 1 #define iMOTHER 2 #define VERBOSE_MENDEL 1 #define VERBOSE_TRANSMITTED 2 typedef struct { int idx[3]; // VCF sample index for father, mother and child int pass; // do all three pass the filters? } trio_t; typedef struct { uint32_t npass, // number of genotypes passing the filter nnon_ref, // number of non-reference genotypes nmendel_err, // number of DNMs / mendelian errors nnovel, // a singleton allele, but observed only in the child. Counted as mendel_err as well. nsingleton, // het mother or father different from everyone else ndoubleton, // het mother+child or father+child different from everyone else (transmitted alleles) nts, ntv, // number of transitions and transversions ndnm_recurrent, // number of recurrent DNMs / mendelian errors (counted as GTs, not sites; in ambiguous cases the allele with smaller AF is chosen) ndnm_hom; // number of homozygous DNMs / mendelian errors } trio_stats_t; typedef struct { trio_stats_t *stats; filter_t *filter; char *expr; } flt_stats_t; typedef struct { kbitset_t *sd_bset; // singleton (1) or doubleton (0) trio? uint32_t nalt, // number of all alternate trios nsd, // number of singleton or doubleton trios *idx; // indexes of the singleton and doubleon trios } alt_trios_t; // for one alt allele typedef struct { int max_alt_trios; // maximum number of alternate trios [1] int malt_trios; alt_trios_t *alt_trios; int argc, filter_logic, regions_is_file, targets_is_file; int nflt_str; char *filter_str, **flt_str; char **argv, *ped_fname, *pfm, *output_fname, *fname, *regions, *targets; bcf_srs_t *sr; bcf_hdr_t *hdr; trio_t *trio; int ntrio, mtrio; flt_stats_t *filters; int nfilters; int32_t *gt_arr, *ac, *ac_trio, *dnm_als; int mgt_arr, mac, mac_trio, mdnm_als; int verbose; FILE *fp_out; } args_t; args_t args; const char *about(void) { return "Calculate transmission rate and other stats in trio children.\n"; } static const char *usage_text(void) { return "\n" "About: Calculate transmission rate in trio children. Use curly brackets to scan\n" " a range of values simultaneously\n" "Usage: bcftools +trio-stats [Plugin Options]\n" "Plugin options:\n" " -a, --alt-trios INT for transmission rate consider only sites with at most this\n" " many alternate trios, 0 for unlimited [0]\n" " -d, --debug TYPE comma-separated list of features: {mendel-errors,transmitted}\n" " -e, --exclude EXPR exclude trios for which the expression is true (one matching sample invalidates a trio)\n" " -i, --include EXPR include trios for which the expression is true (one failing sample invalidates a trio)\n" " -o, --output FILE output file name [stdout]\n" " -p, --ped FILE PED file\n" " -P, --pfm P,F,M sample names of proband, father, and mother\n" " -r, --regions REG restrict to comma-separated list of regions\n" " -R, --regions-file FILE restrict to regions listed in a file\n" " -t, --targets REG similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE similar to -R but streams rather than index-jumps\n" "\n" "Example:\n" " bcftools +trio-stats -p file.ped -i 'GQ>{10,20,30,40,50}' file.bcf\n" "\n"; } static int cmp_trios(const void *_a, const void *_b) { trio_t *a = (trio_t *) _a; trio_t *b = (trio_t *) _b; int i; int amin = a->idx[0]; for (i=1; i<3; i++) if ( amin > a->idx[i] ) amin = a->idx[i]; int bmin = b->idx[0]; for (i=1; i<3; i++) if ( bmin > b->idx[i] ) bmin = b->idx[i]; if ( amin < bmin ) return -1; if ( amin > bmin ) return 1; return 0; } static void parse_ped(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); kstring_t str = {0,0,0}; if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); kstring_t tmp = {0,0,0}; void *has_smpl = khash_str2int_init(); void *has_trio = khash_str2int_init(); int dup_trio_warned = 0; int moff = 0, *off = NULL; do { // familyID sampleID paternalID maternalID sex phenotype population relationship siblings secondOrder thirdOrder children comment // BB03 HG01884 HG01885 HG01956 2 0 ACB child 0 0 0 0 int ncols = ksplit_core(str.s,0,&moff,&off); if ( ncols<4 ) error("Could not parse the ped file: %s\n", str.s); int father = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[2]]); if ( father<0 ) continue; int mother = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[3]]); if ( mother<0 ) continue; int child = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); if ( child<0 ) continue; tmp.l = 0; ksprintf(&tmp,"%s %s %s",&str.s[off[1]],&str.s[off[2]],&str.s[off[3]]); if ( khash_str2int_has_key(has_trio,tmp.s) ) { if ( !dup_trio_warned ) fprintf(stderr,"Warning: The trio \"%s\" is listed multiple times in %s, skipping. (This message is printed only once.)\n",tmp.s,fname); dup_trio_warned = 1; continue; } if ( khash_str2int_has_key(has_smpl,&str.s[off[1]]) ) error("Error: The child \"%s\" is listed in two trios\n",&str.s[off[1]]); khash_str2int_inc(has_smpl,strdup(&str.s[off[1]])); khash_str2int_inc(has_trio,strdup(tmp.s)); args->ntrio++; hts_expand0(trio_t,args->ntrio,args->mtrio,args->trio); trio_t *trio = &args->trio[args->ntrio-1]; trio->idx[iFATHER] = father; trio->idx[iMOTHER] = mother; trio->idx[iCHILD] = child; } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); fprintf(stderr,"Identified %d complete trios in the VCF file\n", args->ntrio); if ( !args->ntrio ) error("No complete trio identified\n"); // sort the sample by index so that they are accessed more or less sequentially qsort(args->trio,args->ntrio,sizeof(trio_t),cmp_trios); khash_str2int_destroy_free(has_smpl); khash_str2int_destroy_free(has_trio); free(tmp.s); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } static void parse_filters(args_t *args) { if ( !args->filter_str ) return; int mflt = 1; args->nflt_str = 1; args->flt_str = (char**) malloc(sizeof(char*)); args->flt_str[0] = strdup(args->filter_str); while (1) { int i, expanded = 0; for (i=args->nflt_str-1; i>=0; i--) { char *exp_beg = strchr(args->flt_str[i], '{'); if ( !exp_beg ) continue; char *exp_end = strchr(exp_beg+1, '}'); if ( !exp_end ) error("Could not parse the expression: %s\n", args->filter_str); char *beg = exp_beg+1, *mid = beg; while ( midflt_str[i], exp_beg - args->flt_str[i], &tmp); kputsn(beg, mid - beg, &tmp); kputs(exp_end+1, &tmp); args->nflt_str++; hts_expand(char*, args->nflt_str, mflt, args->flt_str); args->flt_str[args->nflt_str-1] = tmp.s; beg = ++mid; } expanded = 1; free(args->flt_str[i]); memmove(&args->flt_str[i], &args->flt_str[i+1], (args->nflt_str-i-1)*sizeof(*args->flt_str)); args->nflt_str--; args->flt_str[args->nflt_str] = NULL; } if ( !expanded ) break; } fprintf(stderr,"Collecting data for %d filtering expressions\n", args->nflt_str); } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->regions ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n",args->regions); } if ( args->targets && bcf_sr_set_targets(args->sr, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->targets); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); if ( args->ped_fname ) parse_ped(args, args->ped_fname); else { args->ntrio = 1; args->trio = (trio_t*) calloc(1,sizeof(trio_t)); int ibeg, iend = 0; while ( args->pfm[iend] && args->pfm[iend]!=',' ) iend++; if ( !args->pfm[iend] ) error("Could not parse -P %s\n", args->pfm); args->pfm[iend] = 0; int child = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->pfm); if ( child<0 ) error("No such sample: \"%s\"\n", args->pfm); args->pfm[iend] = ','; ibeg = ++iend; while ( args->pfm[iend] && args->pfm[iend]!=',' ) iend++; if ( !args->pfm[iend] ) error("Could not parse -P %s\n", args->pfm); args->pfm[iend] = 0; int father = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->pfm+ibeg); if ( father<0 ) error("No such sample: \"%s\"\n", args->pfm+ibeg); args->pfm[iend] = ','; ibeg = ++iend; int mother = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->pfm+ibeg); if ( mother<0 ) error("No such sample: \"%s\"\n", args->pfm+ibeg); args->trio[0].idx[iFATHER] = father; args->trio[0].idx[iMOTHER] = mother; args->trio[0].idx[iCHILD] = child; } parse_filters(args); int i; if ( !args->nflt_str ) { args->filters = (flt_stats_t*) calloc(1, sizeof(flt_stats_t)); args->nfilters = 1; args->filters[0].expr = strdup("all"); } else { args->nfilters = args->nflt_str; args->filters = (flt_stats_t*) calloc(args->nfilters, sizeof(flt_stats_t)); for (i=0; infilters; i++) { args->filters[i].filter = filter_init(args->hdr, args->flt_str[i]); args->filters[i].expr = strdup(args->flt_str[i]); // replace tab's with spaces so that the output stays parsable char *tmp = args->filters[i].expr; while ( *tmp ) { if ( *tmp=='\t' ) *tmp = ' '; tmp++; } } } for (i=0; infilters; i++) args->filters[i].stats = (trio_stats_t*) calloc(args->ntrio,sizeof(trio_stats_t)); args->fp_out = !args->output_fname || !strcmp("-",args->output_fname) ? stdout : fopen(args->output_fname,"w"); if ( !args->fp_out ) error("Could not open the file for writing: %s\n", args->output_fname); fprintf(args->fp_out,"# CMD line shows the command line used to generate this output\n"); fprintf(args->fp_out,"# DEF lines define expressions for all tested thresholds\n"); fprintf(args->fp_out,"# FLT* lines report numbers for every threshold and every trio:\n"); i = 0; fprintf(args->fp_out,"# %d) filter id\n", ++i); fprintf(args->fp_out,"# %d) child\n", ++i); fprintf(args->fp_out,"# %d) father\n", ++i); fprintf(args->fp_out,"# %d) mother\n", ++i); fprintf(args->fp_out,"# %d) number of valid trio genotypes (all trio members pass filters, all non-missing)\n", ++i); fprintf(args->fp_out,"# %d) number of non-reference trio GTs (at least one trio member carries an alternate allele)\n", ++i); fprintf(args->fp_out,"# %d) number of DNMs/Mendelian errors\n", ++i); fprintf(args->fp_out,"# %d) number of novel singleton alleles in the child (counted also as DNM / Mendelian error)\n", ++i); fprintf(args->fp_out,"# %d) number of untransmitted trio singletons (one alternate allele present in one parent)\n", ++i); fprintf(args->fp_out,"# %d) number of transmitted trio singletons (one alternate allele present in one parent and the child)\n", ++i); fprintf(args->fp_out,"# %d) number of transitions, all distinct ALT alleles present in the trio are considered\n", ++i); fprintf(args->fp_out,"# %d) number of transversions, all distinct ALT alleles present in the trio are considered\n", ++i); fprintf(args->fp_out,"# %d) overall ts/tv, all distinct ALT alleles present in the trio are considered\n", ++i); fprintf(args->fp_out,"# %d) number of homozygous DNMs/Mendelian errors (likely genotyping errors)\n", ++i); fprintf(args->fp_out,"# %d) number of recurrent DNMs/Mendelian errors (non-inherited alleles present in other samples; counts GTs, not sites)\n", ++i); fprintf(args->fp_out, "CMD\t%s", args->argv[0]); for (i=1; iargc; i++) fprintf(args->fp_out, " %s",args->argv[i]); fprintf(args->fp_out, "\n"); } static void alt_trios_reset(args_t *args, int nals) { int i; hts_expand0(alt_trios_t, nals, args->malt_trios, args->alt_trios); for (i=0; ialt_trios[i]; if ( !tr->idx ) { tr->idx = (uint32_t*)malloc(sizeof(*tr->idx)*args->ntrio); tr->sd_bset = kbs_init(args->ntrio); } else kbs_clear(tr->sd_bset); tr->nsd = 0; tr->nalt = 0; } } static void alt_trios_destroy(args_t *args) { if ( !args->max_alt_trios ) return; int i; for (i=0; imalt_trios; i++) { free(args->alt_trios[i].idx); kbs_destroy(args->alt_trios[i].sd_bset); } free(args->alt_trios); } static inline void alt_trios_add(args_t *args, int itrio, int ial, int is_singleton) { alt_trios_t *tr = &args->alt_trios[ial]; if ( is_singleton ) kbs_insert(tr->sd_bset, tr->nsd); tr->idx[ tr->nsd++ ] = itrio; } static void destroy_data(args_t *args) { int i; for (i=0; infilters; i++) { if ( args->filters[i].filter ) filter_destroy(args->filters[i].filter); free(args->filters[i].stats); free(args->filters[i].expr); } free(args->filters); for (i=0; inflt_str; i++) free(args->flt_str[i]); free(args->flt_str); bcf_sr_destroy(args->sr); alt_trios_destroy(args); free(args->trio); free(args->ac); free(args->ac_trio); free(args->gt_arr); free(args->dnm_als); if ( fclose(args->fp_out)!=0 ) error("Close failed: %s\n", (!args->output_fname || !strcmp("-",args->output_fname)) ? "stdout" : args->output_fname); free(args); } static void report_stats(args_t *args) { int i = 0,j; for (i=0; infilters; i++) { flt_stats_t *flt = &args->filters[i]; fprintf(args->fp_out,"DEF\tFLT%d\t%s\n", i, flt->expr); } for (i=0; infilters; i++) { flt_stats_t *flt = &args->filters[i]; for (j=0; jntrio; j++) { fprintf(args->fp_out,"FLT%d", i); fprintf(args->fp_out,"\t%s",args->hdr->samples[args->trio[j].idx[iCHILD]]); fprintf(args->fp_out,"\t%s",args->hdr->samples[args->trio[j].idx[iFATHER]]); fprintf(args->fp_out,"\t%s",args->hdr->samples[args->trio[j].idx[iMOTHER]]); trio_stats_t *stats = &flt->stats[j]; fprintf(args->fp_out,"\t%d", stats->npass); fprintf(args->fp_out,"\t%d", stats->nnon_ref); fprintf(args->fp_out,"\t%d", stats->nmendel_err); fprintf(args->fp_out,"\t%d", stats->nnovel); fprintf(args->fp_out,"\t%d", stats->nsingleton); fprintf(args->fp_out,"\t%d", stats->ndoubleton); fprintf(args->fp_out,"\t%d", stats->nts); fprintf(args->fp_out,"\t%d", stats->ntv); fprintf(args->fp_out,"\t%.2f", stats->ntv ? (float)stats->nts/stats->ntv : INFINITY); fprintf(args->fp_out,"\t%d", stats->ndnm_hom); fprintf(args->fp_out,"\t%d", stats->ndnm_recurrent); fprintf(args->fp_out,"\n"); } } } static inline int parse_genotype(int32_t *arr, int ngt1, int idx, int als[2]) { int32_t *ptr = arr + ngt1 * idx; if ( bcf_gt_is_missing(ptr[0]) ) return -1; als[0] = bcf_gt_allele(ptr[0]); // treat haploid GTs as homozygous diploid if ( ngt1==1 || ptr[1]==bcf_int32_vector_end ) { als[1] = als[0]; return 0; } if ( bcf_gt_is_missing(ptr[1]) ) return -1; als[1] = bcf_gt_allele(ptr[1]); return 0; } static void process_record(args_t *args, bcf1_t *rec, flt_stats_t *flt) { int i,j; // Find out which trios pass and if the site passes if ( flt->filter ) { uint8_t *smpl_pass = NULL; int pass_site = filter_test(flt->filter, rec, (const uint8_t**) &smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) { if ( pass_site ) { if ( !smpl_pass ) return; pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( smpl_pass[idx] ) { pass_trio = 0; break; } } args->trio[i].pass = pass_trio; if ( pass_trio ) pass_site = 1; } if ( !pass_site ) return; } else for (i=0; intrio; i++) args->trio[i].pass = 1; } else if ( !pass_site ) return; else if ( smpl_pass ) { pass_site = 0; for (i=0; intrio; i++) { int pass_trio = 1; for (j=0; j<3; j++) { int idx = args->trio[i].idx[j]; if ( !smpl_pass[idx] ) { pass_trio = 0; break; } } args->trio[i].pass = pass_trio; if ( pass_trio ) pass_site = 1; } if ( !pass_site ) return; } else for (i=0; intrio; i++) args->trio[i].pass = 1; } // Find out the allele counts. Try to use INFO/AC, if not present, determine from the genotypes hts_expand(int, rec->n_allele, args->mac, args->ac); if ( !bcf_calc_ac(args->hdr, rec, args->ac, BCF_UN_INFO|BCF_UN_FMT) ) return; hts_expand(int, rec->n_allele, args->mac_trio, args->ac_trio); hts_expand(int, rec->n_allele, args->mdnm_als, args->dnm_als); // Get the genotypes int ngt = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); if ( ngt<0 ) return; int ngt1 = ngt / rec->n_sample; // For ts/tv: numeric code of the reference allele, -1 for insertions int ref = !rec->d.allele[0][1] ? bcf_acgt2int(*rec->d.allele[0]) : -1; int star_allele = -1; for (i=1; in_allele; i++) if ( !rec->d.allele[i][1] && rec->d.allele[i][0]=='*' ) { star_allele = i; break; } // number of non-reference trios if ( args->max_alt_trios ) alt_trios_reset(args, rec->n_allele); // Run the stats for (i=0; intrio; i++) { if ( flt->filter && !args->trio[i].pass ) continue; trio_stats_t *stats = &flt->stats[i]; // Determine the alternate allele and the genotypes, skip if any of the alleles is missing. // the order is: child, father, mother int als[6], *als_child = als, *als_father = als+2, *als_mother = als+4; if ( parse_genotype(args->gt_arr, ngt1, args->trio[i].idx[iCHILD], als_child) < 0 ) continue; if ( parse_genotype(args->gt_arr, ngt1, args->trio[i].idx[iFATHER], als_father) < 0 ) continue; if ( parse_genotype(args->gt_arr, ngt1, args->trio[i].idx[iMOTHER], als_mother) < 0 ) continue; stats->npass++; // Has the trio an alternate allele other than *? int has_star_allele = 0, has_nonref = 0; memset(args->ac_trio,0,rec->n_allele*sizeof(*args->ac_trio)); for (j=0; j<6; j++) { if ( als[j]==star_allele ) { has_star_allele = 1; continue; } if ( als[j]!=0 ) has_nonref = 1; args->ac_trio[ als[j] ]++; } if ( !has_nonref ) continue; // only ref or * in this trio stats->nnon_ref++; // Calculate ts/tv. It does the right thing and handles also HetAA genotypes if ( ref != -1 ) { int has_ts = 0, has_tv = 0; for (j=0; j<6; j++) { if ( als[j]==0 || als[j]==star_allele ) continue; if ( als[j] >= rec->n_allele ) error("The GT index is out of range at %s:%"PRId64" in %s\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1,args->hdr->samples[args->trio[i].idx[j/2]]); if ( rec->d.allele[als[j]][1] ) continue; int alt = bcf_acgt2int(rec->d.allele[als[j]][0]); if ( abs(ref-alt)==2 ) has_ts = 1; else has_tv = 1; } if ( has_ts ) stats->nts++; if ( has_tv ) stats->ntv++; } // Skip some stats if the star allele is present as it was already checked at the primary record, we do not want to count the same // thing multiple times. There can be other alternate allele, but we ignore that for simplicity. if ( has_star_allele ) continue; // Detect mendelian errors int a0F = als_child[0]==als_father[0] || als_child[0]==als_father[1] ? 1 : 0; int a1M = als_child[1]==als_mother[0] || als_child[1]==als_mother[1] ? 1 : 0; if ( !a0F || !a1M ) { int a0M = als_child[0]==als_mother[0] || als_child[0]==als_mother[1] ? 1 : 0; int a1F = als_child[1]==als_father[0] || als_child[1]==als_father[1] ? 1 : 0; if ( !a0M || !a1F ) { stats->nmendel_err++; int dnm_hom = 0; if ( als_child[0]==als_child[1] ) { stats->ndnm_hom++; dnm_hom = 1; } int culprit; // neglecting the unlikely possibility of alt het 1/2 DNM genotype if ( !a0F && !a0M ) culprit = als_child[0]; else if ( !a1F && !a1M ) culprit = als_child[1]; else if ( args->ac[als_child[0]] < args->ac[als_child[1]] ) culprit = als_child[0]; else culprit = als_child[1]; int dnm_recurrent = 0; if ( (!dnm_hom && args->ac[culprit]>1) || (dnm_hom && args->ac[culprit]>2) ) { stats->ndnm_recurrent++; dnm_recurrent = 1; } if ( args->verbose & VERBOSE_MENDEL ) fprintf(args->fp_out,"MERR\t%s\t%"PRId64"\t%s\t%s\t%s\t%s\t%s\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1, args->hdr->samples[args->trio[i].idx[iCHILD]], args->hdr->samples[args->trio[i].idx[iFATHER]], args->hdr->samples[args->trio[i].idx[iMOTHER]], dnm_hom ? "HOM" : "-", dnm_recurrent ? "RECURRENT" : "-" ); } } // Is this a singleton, doubleton, neither? for (j=0; jn_allele; j++) { if ( !args->ac_trio[j] ) continue; if ( args->max_alt_trios ) args->alt_trios[j].nalt++; if ( args->ac_trio[j]==1 ) // singleton (in parent) or novel (in child) { if ( als_child[0]==j || als_child[1]==j ) stats->nnovel++; else { if ( !args->max_alt_trios ) { stats->nsingleton++; if ( args->verbose & VERBOSE_TRANSMITTED ) fprintf(args->fp_out,"TRANSMITTED\t%s\t%"PRId64"\t%s\t%s\t%s\tNO\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1, args->hdr->samples[args->trio[i].idx[iCHILD]], args->hdr->samples[args->trio[i].idx[iFATHER]], args->hdr->samples[args->trio[i].idx[iMOTHER]] ); } else alt_trios_add(args, i,j,1); } } else if ( args->ac_trio[j]==2 ) // possibly a doubleton { if ( (als_child[0]!=j && als_child[1]!=j) || (als_child[0]==j && als_child[1]==j) ) continue; if ( (als_father[0]==j && als_father[1]==j) || (als_mother[0]==j && als_mother[1]==j) ) continue; if ( !args->max_alt_trios ) { stats->ndoubleton++; if ( args->verbose & VERBOSE_TRANSMITTED ) fprintf(args->fp_out,"TRANSMITTED\t%s\t%"PRId64"\t%s\t%s\t%s\tYES\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1, args->hdr->samples[args->trio[i].idx[iCHILD]], args->hdr->samples[args->trio[i].idx[iFATHER]], args->hdr->samples[args->trio[i].idx[iMOTHER]] ); } else alt_trios_add(args, i,j,0); } } } if ( args->max_alt_trios ) { for (j=0; jn_allele; j++) { alt_trios_t *tr = &args->alt_trios[j]; if ( !tr->nsd || tr->nalt > args->max_alt_trios ) continue; for (i=0; insd; i++) { int itr = tr->idx[i]; trio_stats_t *stats = &flt->stats[itr]; if ( kbs_exists(tr->sd_bset,i) ) { stats->nsingleton++; if ( args->verbose & VERBOSE_TRANSMITTED ) fprintf(args->fp_out,"TRANSMITTED\t%s\t%"PRId64"\t%s\t%s\t%s\tNO\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1, args->hdr->samples[args->trio[itr].idx[iCHILD]], args->hdr->samples[args->trio[itr].idx[iFATHER]], args->hdr->samples[args->trio[itr].idx[iMOTHER]] ); } else { stats->ndoubleton++; if ( args->verbose & VERBOSE_TRANSMITTED ) fprintf(args->fp_out,"TRANSMITTED\t%s\t%"PRId64"\t%s\t%s\t%s\tYES\n", bcf_seqname(args->hdr,rec),(int64_t) rec->pos+1, args->hdr->samples[args->trio[itr].idx[iCHILD]], args->hdr->samples[args->trio[itr].idx[iFATHER]], args->hdr->samples[args->trio[itr].idx[iMOTHER]] ); } } } } } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; static struct option loptions[] = { {"debug",required_argument,0,'d'}, {"alt-trios",required_argument,0,'a'}, {"include",required_argument,0,'i'}, {"exclude",required_argument,0,'e'}, {"output",required_argument,NULL,'o'}, {"ped",required_argument,NULL,'p'}, {"pfm",required_argument,NULL,'P'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {NULL,0,NULL,0} }; int c, i; while ((c = getopt_long(argc, argv, "P:p:o:s:i:e:r:R:t:T:a:d:",loptions,NULL)) >= 0) { switch (c) { case 'd': { int n; char **tmp = hts_readlist(optarg, 0, &n); for(i=0; iverbose |= VERBOSE_MENDEL; else if ( !strcasecmp(tmp[i],"transmitted") ) args->verbose |= VERBOSE_TRANSMITTED; else error("Error: The argument \"%s\" to option --debug is not recognised\n", tmp[i]); free(tmp[i]); } free(tmp); break; } case 'a': args->max_alt_trios = atoi(optarg); break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'p': args->ped_fname = optarg; break; case 'P': args->pfm = optarg; break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s", usage_text()); } } else if ( optind+1!=argc ) error("%s", usage_text()); else args->fname = argv[optind]; if ( !args->ped_fname && !args->pfm ) error("Missing the -p or -P option\n"); init_data(args); while ( bcf_sr_next_line(args->sr) ) { bcf1_t *rec = bcf_sr_get_line(args->sr,0); for (i=0; infilters; i++) process_record(args, rec, &args->filters[i]); } report_stats(args); destroy_data(args); return 0; } bcftools-1.21/plugins/trio-switch-rate.c000066400000000000000000000216771467060157400203310ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include "bcftools.h" typedef struct { int father, mother, child; // VCF sample index int prev, ipop; uint32_t err, nswitch, ntest; } trio_t; typedef struct { char *name; uint32_t err, nswitch, ntest, ntrio; float pswitch; } pop_t; typedef struct { int argc; char **argv; bcf_hdr_t *hdr; trio_t *trio; int ntrio, mtrio; int32_t *gt_arr; int npop; pop_t *pop; int mgt_arr, prev_rid; } args_t; args_t args; const char *about(void) { return "Calculate phase switch rate in trio samples, children samples must have phased GTs.\n"; } const char *usage(void) { return "\n" "About: Calculate phase switch rate in trio children.\n" "Usage: bcftools +trio-switch-rate [General Options] -- [Plugin Options]\n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Plugin options:\n" " -p, --ped PED file with optional 7th column to group\n" " results by population\n" "\n" "Example:\n" " bcftools +trio-switch-rate file.bcf -- -p file.ped\n" "\n"; } void parse_ped(args_t *args, char *fname) { htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); kstring_t str = {0,0,0}; if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); void *pop2i = khash_str2int_init(); int moff = 0, *off = NULL; do { // familyID sampleID paternalID maternalID sex phenotype population relationship siblings secondOrder thirdOrder children comment // BB03 HG01884 HG01885 HG01956 2 0 ACB child 0 0 0 0 int ncols = ksplit_core(str.s,0,&moff,&off); if ( ncols<4 ) error("Could not parse the ped file: %s\n", str.s); int father = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[2]]); if ( father<0 ) continue; int mother = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[3]]); if ( mother<0 ) continue; int child = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); if ( child<0 ) continue; args->ntrio++; hts_expand0(trio_t,args->ntrio,args->mtrio,args->trio); trio_t *trio = &args->trio[args->ntrio-1]; trio->father = father; trio->mother = mother; trio->child = child; if (ncols>6) { char *pop_name = &str.s[off[6]]; if ( !khash_str2int_has_key(pop2i,pop_name) ) { pop_name = strdup(&str.s[off[6]]); khash_str2int_set(pop2i,pop_name,args->npop); args->npop++; args->pop = (pop_t*) realloc(args->pop,args->npop*sizeof(*args->pop)); memset(args->pop+args->npop-1,0,sizeof(*args->pop)); args->pop[args->npop-1].name = pop_name; } khash_str2int_get(pop2i,pop_name,&trio->ipop); args->pop[trio->ipop].ntrio++; } } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); khash_str2int_destroy(pop2i); free(str.s); free(off); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); } int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { memset(&args,0,sizeof(args_t)); args.argc = argc; args.argv = argv; args.prev_rid = -1; args.hdr = in; char *ped_fname = NULL; static struct option loptions[] = { {"ped",required_argument,NULL,'p'}, {0,0,0,0} }; int c; while ((c = getopt_long(argc, argv, "?hp:",loptions,NULL)) >= 0) { switch (c) { case 'p': ped_fname = optarg; break; case 'h': case '?': default: error("%s", usage()); break; } } if ( !ped_fname ) error("Expected the -p option\n"); parse_ped(&args, ped_fname); return 1; } typedef struct { int a, b, phased; } gt_t; int parse_genotype(gt_t *gt, int32_t *ptr); inline int parse_genotype(gt_t *gt, int32_t *ptr) { if ( ptr[0]==bcf_gt_missing ) return 0; if ( ptr[1]==bcf_gt_missing ) return 0; if ( ptr[1]==bcf_int32_vector_end ) return 0; gt->phased = bcf_gt_is_phased(ptr[1]) ? 1 : 0; gt->a = bcf_gt_allele(ptr[0]); if ( gt->a > 1 ) return 0; // consider only the first two alleles at biallelic sites gt->b = bcf_gt_allele(ptr[1]); if ( gt->b > 1 ) return 0; return 1; } bcf1_t *process(bcf1_t *rec) { int ngt = bcf_get_genotypes(args.hdr, rec, &args.gt_arr, &args.mgt_arr); if ( ngt<0 ) return NULL; ngt /= bcf_hdr_nsamples(args.hdr); if ( ngt!=2 ) return NULL; int i; if ( rec->rid!=args.prev_rid ) { args.prev_rid = rec->rid; for (i=0; ichild) ) continue; if ( !child.phased ) continue; if ( child.a+child.b != 1 ) continue; // child is not a het if ( !parse_genotype(&father, args.gt_arr + ngt*trio->father) ) continue; if ( !parse_genotype(&mother, args.gt_arr + ngt*trio->mother) ) continue; if ( father.a+father.b == 1 && mother.a+mother.b == 1 ) continue; // both parents are hets if ( father.a+father.b == mother.a+mother.b ) { trio->err++; continue; } // mendelian error int test_phase = 0; if ( father.a==father.b ) test_phase = 1 + (child.a==father.a); else if ( mother.a==mother.b ) test_phase = 1 + (child.b==mother.a); if ( trio->prev > 0 ) { if ( trio->prev!=test_phase ) trio->nswitch++; } trio->ntest++; trio->prev = test_phase; } return NULL; } void destroy(void) { int i; printf("# This file was produced by: bcftools +trio-switch-rate(%s+htslib-%s)\n", bcftools_version(),hts_version()); printf("# The command line was:\tbcftools +trio-switch-rate %s", args.argv[0]); for (i=1; ifather), bcf_hdr_int2id(args.hdr,BCF_DT_SAMPLE,trio->mother), bcf_hdr_int2id(args.hdr,BCF_DT_SAMPLE,trio->child), trio->ntest, trio->err, trio->nswitch, trio->ntest ? trio->nswitch*100./trio->ntest : 0 ); if (args.npop) { pop_t *pop = &args.pop[trio->ipop]; pop->err += trio->err; pop->nswitch += trio->nswitch; pop->ntest += trio->ntest; pop->pswitch += trio->ntest ? trio->nswitch*100./trio->ntest : 0; } } printf("# POP\tpopulation or other grouping defined by an optional 7-th column of the PED file\n"); printf("# POP\t[2]Name\t[3]Number of trios\t[4]avgTested\t[5]avgMendelian Errors\t[6]avgSwitch\t[7]avgSwitch (%%)\n"); for (i=0; iname,pop->ntrio, (float)pop->ntest/pop->ntrio,(float)pop->err/pop->ntrio,(float)pop->nswitch/pop->ntrio, pop->pswitch/pop->ntrio); } for (i=0; i Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Add custom INFO field with the distance to the nearest variant */ #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "vcfbuf.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define DIR_NEAREST 0 #define DIR_FWD 1 #define DIR_REV 2 #define DIR_BOTH 3 typedef struct { char *tag; int argc, region_is_file, target_is_file, output_type, clevel; int regions_overlap, targets_overlap, direction; int32_t fwd_dist, rev_dist; char **argv, *region, *target, *fname, *output_fname; char *filter_str; filter_t *filter; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) htsFile *out_fh; bcf_hdr_t *hdr; bcf_srs_t *sr; vcfbuf_t *buf; char *index_fn; int write_index; } args_t; const char *about(void) { return "Annotate sites with distance to the nearest variant\n"; } static const char *usage_text(void) { return "\n" "About: Annotate sites with distance to the nearest variant\n" "Usage: bcftools +variant-distance [Options]\n" "Options:\n" " -d, --direction DIRECTION Directionality: nearest, fwd, rev, both (adds a Number=2 tag) [nearest]\n" " -n, --tag-name STR The tag name to be added [DIST]\n" "Common options:\n" " -e, --exclude EXPR Exclude sites for which the expression is true\n" " -i, --include EXPR Include only sites for which the expression is true\n" " -o, --output FILE Write output to the FILE [standard output]\n" " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n" " -r, --regions REGION Restrict to comma-separated list of regions\n" " -R, --regions-file FILE Restrict to regions listed in a file\n" " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n" " -t, --targets REGION Similar to -r but streams rather than index-jumps\n" " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n" " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n" " -W, --write-index[=FMT] Automatically index the output files [off]\n" "Examples:\n" " bcftools +variant-distance input.bcf -Ob -o output.bcf\n" "\n"; } static void init_data(args_t *args) { args->sr = bcf_sr_init(); if ( args->region ) { args->sr->require_index = 1; if ( bcf_sr_set_regions(args->sr, args->region, args->region_is_file)<0 ) error("Failed to read the regions: %s\n",args->region); } if ( args->target && bcf_sr_set_targets(args->sr, args->target, args->target_is_file, 0)<0 ) error("Failed to read the targets: %s\n",args->target); if ( !bcf_sr_add_reader(args->sr,args->fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); args->hdr = bcf_sr_get_header(args->sr,0); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); if ( !args->tag ) args->tag = strdup("DIST"); int nval = 1; const char *desc = NULL; if ( args->direction==DIR_FWD ) desc = "next"; else if ( args->direction==DIR_REV ) desc = "previous"; else if ( args->direction==DIR_NEAREST) desc = "nearest"; else desc = "previous and next", nval = 2; bcf_hdr_printf(args->hdr,"##INFO=",args->tag,nval,desc); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( bcf_hdr_write(args->out_fh, args->hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr,args->output_fname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); args->buf = vcfbuf_init(args->hdr, 0); vcfbuf_set(args->buf,VCFBUF_DUMMY,1); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); bcf_sr_destroy(args->sr); vcfbuf_destroy(args->buf); free(args->tag); free(args); } static void flush(args_t *args, int n) { int32_t val[2]; int nval = 0, i; if ( args->direction==DIR_FWD && args->fwd_dist ) nval = 1, val[0] = args->fwd_dist; else if ( args->direction==DIR_REV && args->rev_dist ) nval = 1, val[0] = args->rev_dist; else if ( args->direction==DIR_BOTH && (args->fwd_dist||args->rev_dist) ) nval = 2, val[0] = args->rev_dist, val[1] = args->fwd_dist; else if ( args->direction==DIR_NEAREST && (args->fwd_dist||args->rev_dist) ) { if ( !args->fwd_dist ) val[0] = args->rev_dist; else if ( !args->rev_dist ) val[0] = args->fwd_dist; else if ( args->rev_dist < args->fwd_dist ) val[0] = args->rev_dist; else val[0] = args->fwd_dist; nval = 1; } for (i=0; ibuf, 1); if ( nval ) { if ( bcf_update_info_int32(args->hdr,rec,args->tag,val,nval)!=0 ) error("[%s] Error: failed to update INFO/%s at %s:%"PRIhts_pos"\n",__func__,args->tag,bcf_seqname(args->hdr,rec),rec->pos+1); } if ( bcf_write(args->out_fh,args->hdr,rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } } static void process(args_t *args, int done) { if ( done ) { // If the buffer is not empty, all records must be duplicate positions and // the previous site may or may not be set args->fwd_dist = 0; flush(args, vcfbuf_nsites(args->buf)); return; } // Do filtering when requested bcf1_t *rec = bcf_sr_get_line(args->sr,0); if ( args->filter ) { int pass = filter_test(args->filter, rec, NULL); if ( args->filter_logic==FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) return; } bcf_sr_t *sr = bcf_sr_get_reader(args->sr,0); sr->buffer[0] = vcfbuf_push(args->buf, rec); // Find the block of duplicate records (the same chr+position) int i, n = vcfbuf_nsites(args->buf); bcf1_t *rec0 = vcfbuf_peek(args->buf, 0); for (i=1; ibuf, i); if ( rec->rid != rec0->rid ) break; if ( rec->pos != rec0->pos ) break; } if ( i==n ) return; // cannot flush yet, either a single record or all duplicates if ( rec->rid != rec0->rid ) // the new record is a different chr { args->fwd_dist = 0; flush(args, i); args->rev_dist = 0; return; } // the new record is a different pos args->fwd_dist = rec->pos - rec0->pos; flush(args, i); args->rev_dist = args->fwd_dist; } int run(int argc, char **argv) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_type = FT_VCF; args->output_fname = "-"; args->clevel = -1; static struct option loptions[] = { {"direction",required_argument,NULL,'d'}, {"tag-name",required_argument,NULL,'n'}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,3}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,2}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; int c; char *tmp; while ((c = getopt_long(argc, argv, "r:R:t:T:o:O:n:d:W::",loptions,NULL)) >= 0) { switch (c) { case 'd': if ( !strcasecmp("nearest",optarg) ) args->direction = DIR_NEAREST; else if ( !strcasecmp("fwd",optarg) ) args->direction = DIR_FWD; else if ( !strcasecmp("rev",optarg) ) args->direction = DIR_REV; else if ( !strcasecmp("both",optarg) ) args->direction = DIR_BOTH; else error("Unknown argument to --direction: %s\n",optarg); break; case 'n': args->tag = strdup(optarg); break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'T': args->target_is_file = 1; // fall-through case 't': args->target = optarg; break; case 'R': args->region_is_file = 1; // fall-through case 'r': args->region = optarg; break; case 2 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 3 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': default: error("%s", usage_text()); break; } } if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else { error("%s",usage_text()); } } else if ( optind+1!=argc ) error("%s",usage_text()); else args->fname = argv[optind]; init_data(args); while ( bcf_sr_next_line(args->sr) ) process(args,0); process(args,1); destroy_data(args); return 0; } bcftools-1.21/plugins/variantkey-hex.c000066400000000000000000000104471467060157400200540ustar00rootroot00000000000000/* plugins/variantkey-hex.c -- Generate unsorted VariantKey lookup tables files in hexadecimal format. Copyright (C) 2017-2018 GENOMICS plc. Author: Nicola Asuni Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include "../variantkey.h" const char *FILE_VKRS = "vkrs.unsorted.hex"; const char *FILE_RSVK = "rsvk.unsorted.hex"; const char *FILE_NRVK = "nrvk.unsorted.tsv"; FILE *fp_vkrs; // VariantKey -> rsID FILE *fp_rsvk; // rsID -> VariantKey FILE *fp_nrvk; // VariantKey non-reversible map (maps VariantKey to REF and ALT) static uint64_t numvar; // number of variants static uint64_t nrv; // number of non-reversible variants bcf_hdr_t *in_hdr; const char *about(void) { return "Generate VariantKey index files\n"; } const char *usage(void) { return "\n" "About: Generate unsorted VariantKey lookup tables files in hexadecimal format.\n" "Usage: bcftools +variantkey-hex [General Options] \n" "Options:\n" " run \"bcftools plugin\" for a list of common options\n" "\n" "Example:\n" " bcftools +variantkey-hex in.vcf\n" "\n"; } // Called once at startup, it initializes local variables. // Return 1 to suppress VCF/BCF header from printing, 0 otherwise. int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) { in_hdr = in; numvar = 0; char path[1024]; char dir[1024] = "./"; if (argc > 1) { strcpy(dir, argv[1]); } strcpy(path, dir); strcat(path, FILE_VKRS); fp_vkrs = fopen(path, "w"); if (!fp_vkrs) { fprintf(stderr, "%s: %s\n", path, strerror(errno)); } strcpy(path, dir); strcat(path, FILE_RSVK); fp_rsvk = fopen(path, "w"); if (!fp_rsvk) { fprintf(stderr, "%s: %s\n", path, strerror(errno)); } strcpy(path, dir); strcat(path, FILE_NRVK); fp_nrvk = fopen(path, "w"); if (!fp_nrvk) { fprintf(stderr, "%s: %s\n", path, strerror(errno)); } return 1; } // Called for each VCF record. Return rec to output the line or NULL to suppress output. bcf1_t *process(bcf1_t *rec) { int len_ref = strlen(rec->d.allele[0]); int len_alt = strlen(rec->d.allele[1]); uint64_t vk = variantkey( in_hdr->id[BCF_DT_CTG][rec->rid].key, strlen(in_hdr->id[BCF_DT_CTG][rec->rid].key), rec->pos, rec->d.allele[0], len_ref, rec->d.allele[1], len_alt); char *ptr = rec->d.id; ptr += 2; // remove 'rs' uint32_t rs = (uint32_t)strtoul(ptr, NULL, 10); fprintf(fp_vkrs, "%016" PRIx64 "\t%08" PRIx32 "\n", vk, rs); // map VariantKey to rsID fprintf(fp_rsvk, "%08" PRIx32 "\t%016" PRIx64 "\n", rs, vk); // map rsID to VariantKey if (vk & 1) { // map VariantKey to REF and ALT fprintf(fp_nrvk, "%016" PRIx64 "\t%s\t%s\n", vk, rec->d.allele[0], rec->d.allele[1]); nrv++; } numvar++; return NULL; } void destroy(void) { fclose(fp_vkrs); fclose(fp_rsvk); printf("VariantKeys: %" PRIu64 "\n", numvar); printf("Non-reversible VariantKeys: %" PRIu64 "\n", nrv); } bcftools-1.21/polysomy.c000066400000000000000000001016551467060157400153310ustar00rootroot00000000000000/* The MIT License Copyright (c) 2013-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "peakfit.h" typedef struct { int nvals; // all values, including RR,AA peaks double *xvals; // pointer to args_t.xvals double *yvals; int copy_number; // heuristics to skip futile CN1 fits when no het peak is detected int irr, ira, iaa; // chop off RR and AA peaks char *chr; } dist_t; typedef struct { int ndist, nbins, ra_rr_scaling, smooth; double *xvals; dist_t *dist; char **argv, *output_dir; double fit_th, peak_symmetry, cn_penalty, min_peak_size, min_fraction; int argc, plot, verbose, regions_is_file, targets_is_file, include_aa, force_cn; int regions_overlap, targets_overlap; char *dat_fname, *fname, *regions_list, *targets_list, *sample; FILE *dat_fp; } args_t; FILE *open_file(char **fname, const char *mode, const char *fmt, ...) HTS_FORMAT(HTS_PRINTF_FMT, 3, 4); static void init_dist(args_t *args, dist_t *dist, int verbose) { // isolate RR and AA peaks and rescale so that they are comparable to hets int i, irr, iaa, n = dist->nvals; // smooth the distribution, this is just to find the peaks double *tmp = (double*) malloc(sizeof(double)*n); int win = args->smooth ? abs(args->smooth)*2 + 1 : 7; // must be an odd number int hwin = win/2; double avg = tmp[0] = dist->yvals[0]; for (i=1; iyvals[2*i-1]; tmp[i] = avg/(2*i+1); } avg = 0; for (i=0; iyvals[i]; if ( i>=win-1 ) { tmp[i-hwin] = avg/win; avg -= dist->yvals[i-win+1]; } } for (i=n-hwin; iyvals[i-hwin]; hwin--; tmp[i] = avg/(2*hwin+1); avg -= dist->yvals[i-hwin]; } // find the extremes; first a simple approach: find a gap for (irr=0,i=0; i=n/2; i--) if ( tmp[i] < tmp[iaa] ) iaa = i; irr += win*0.5; iaa += win*0.5; if ( iaa>=n ) iaa = n-1; if ( irr>=iaa ) error("FIXME: oops, dist normalization failed for %s: %d vs %d\n", dist->chr,irr,iaa); // we may need to be smarter if ( args->smooth>0 ) for (i=0; iyvals[i] = tmp[i]; free(tmp); // clean the data: the AA peak is occasionally not centered at 1.0 but is closer to the center, chop off int imax_aa = iaa; for (i=iaa; iyvals[imax_aa] < dist->yvals[i] ) imax_aa = i; dist->nvals = imax_aa+1; if ( iaa>=dist->nvals ) iaa = dist->nvals-1; // find the maximum and scale the peaks (first draft: no attempt to join the segments smootly) double max_rr = 0, max_aa = 0, max_ra = 0, srr = 0, saa = 0, sra = 0; for (i=0; iyvals[i]; if ( max_rr < dist->yvals[i] ) max_rr = dist->yvals[i]; } for (i=irr; i<=iaa; i++) { sra += dist->yvals[i]; if ( max_ra < dist->yvals[i] ) max_ra = dist->yvals[i]; } for (i=iaa+1; iyvals[i]; if ( max_aa < dist->yvals[i] ) max_aa = dist->yvals[i]; } // Does the het peak exist at all? Usually the numbers are as follows: // 1: cn=0 ra/rr=0.205730 aa/ra=0.674922 nra=7066 // 20: cn=0 ra/rr=0.258019 aa/ra=0.548929 nra=2381 // X: cn=0 ra/rr=0.005976 aa/ra=44.116667 nra=60 // Y: cn=0 ra/rr=0.008316 aa/ra=7.250000 nra=12 // MT: cn=0 ra/rr=0.013699 aa/ra=0.666667 nra=3 if ( !args->ra_rr_scaling ) max_ra = max_aa = max_rr; if ( !sra || (sra/srr<0.1 && saa/sra>1.0) ) // too few hets, CN1 { max_ra = max_aa; dist->copy_number = 1; } else if ( sra/srr<0.1 || saa/sra>1.0 ) { max_ra = max_aa; dist->copy_number = -1; // unknown copy number } if ( max_rr ) for (i=0; iyvals[i] /= max_rr; if ( max_ra ) for (i=irr; i<=iaa; i++) dist->yvals[i] /= max_ra; if ( max_aa ) for (i=iaa+1; iyvals[i] /= max_aa; dist->irr = irr; dist->iaa = iaa; dist->ira = n*0.5; if ( verbose ) fprintf(stderr,"%s:\t irr,ira,iaa=%.2f,%.2f,%.2f \t cn=%2d \t ra/rr=%f \t aa/ra=%f \t nra=%d\n", dist->chr, dist->xvals[irr],dist->xvals[dist->ira],dist->xvals[iaa], dist->copy_number,sra/srr,saa/sra, (int)sra); } static void init_data(args_t *args) { bcf_srs_t *files = bcf_sr_init(); if ( args->regions_list ) { bcf_sr_set_opt(files,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(files, args->regions_list, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { bcf_sr_set_opt(files,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(files, args->targets_list, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( !bcf_sr_add_reader(files, args->fname) ) error("Failed to read from %s: %s\n", !strcmp("-",args->fname)?"standard input":args->fname,bcf_sr_strerror(files->errnum)); bcf_hdr_t *hdr = files->readers[0].header; if ( !args->sample ) { if ( bcf_hdr_nsamples(hdr)>1 ) error("Missing the option -s, --sample\n"); args->sample = hdr->samples[0]; } else if ( bcf_hdr_id2int(hdr,BCF_DT_SAMPLE,args->sample)<0 ) error("No such sample: %s\n", args->sample); int ret = bcf_hdr_set_samples(hdr, args->sample, 0); if ( ret<0 ) error("Error setting the sample: %s\n", args->sample); if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,bcf_hdr_id2int(hdr,BCF_DT_ID,"BAF")) ) error("The tag FORMAT/BAF is not present in the VCF: %s\n", args->fname); int i; args->xvals = (double*) calloc(args->nbins,sizeof(double)); for (i=0; inbins; i++) args->xvals[i] = 1.0*i/(args->nbins-1); // collect BAF distributions for all chromosomes int idist = -1, nbaf = 0, nprocessed = 0, ntotal = 0, prev_chr = -1; float *baf = NULL; while ( bcf_sr_next_line(files) ) { ntotal++; bcf1_t *line = bcf_sr_get_line(files,0); if ( bcf_get_format_float(hdr,line,"BAF",&baf,&nbaf) != 1 ) continue; if ( bcf_float_is_missing(baf[0]) ) continue; nprocessed++; if ( prev_chr==-1 || prev_chr!=line->rid ) { // new chromosome idist = args->ndist++; args->dist = (dist_t*) realloc(args->dist, sizeof(dist_t)*args->ndist); memset(&args->dist[idist],0,sizeof(dist_t)); args->dist[idist].chr = strdup(bcf_seqname(hdr,line)); args->dist[idist].yvals = (double*) calloc(args->nbins,sizeof(double)); args->dist[idist].xvals = args->xvals; args->dist[idist].nvals = args->nbins; prev_chr = line->rid; } int bin = baf[0]*(args->nbins-1); args->dist[idist].yvals[bin]++; // the distribution } free(baf); bcf_sr_destroy(files); for (idist=0; idistndist; idist++) { #if 0 int j; for (j=0; jnbins; j++) { double x = args->dist[idist].xvals[j]; args->dist[idist].yvals[j] = exp(-(x-0.5)*(x-0.5)/1e-3); } #endif init_dist(args, &args->dist[idist],args->verbose); } args->dat_fp = open_file(&args->dat_fname,"w","%s/dist.dat", args->output_dir); fprintf(args->dat_fp, "# This file was produced by: bcftools polysomy(%s+htslib-%s), the command line was:\n", bcftools_version(),hts_version()); fprintf(args->dat_fp, "# \t bcftools %s ", args->argv[0]); for (i=1; iargc; i++) fprintf(args->dat_fp, " %s",args->argv[i]); fprintf(args->dat_fp,"\n#\n"); fprintf(args->dat_fp,"# DIST\t[2]Chrom\t[3]BAF\t[4]Normalized Count\n"); fprintf(args->dat_fp,"# FIT\t[2]Goodness of Fit\t[3]iFrom\t[4]iTo\t[5]The Fitted Function\n"); fprintf(args->dat_fp,"# CN\t[2]Chrom\t[3]Estimated Copy Number\t[4]Absolute fit deviation\n"); char *fname = NULL; FILE *fp = open_file(&fname,"w","%s/dist.py", args->output_dir); //-------- matplotlib script -------------- fprintf(fp, "#!/usr/bin/env python\n" "#\n" "import matplotlib as mpl\n" "mpl.use('Agg')\n" "import matplotlib.pyplot as plt\n" "import csv,sys,argparse\n" "from math import exp\n" "\n" "outdir = '%s'\n" "\n" "def read_dat(dat,fit,cn):\n" " csv.register_dialect('tab', delimiter='\t', quoting=csv.QUOTE_NONE)\n" " with open(outdir+'/dist.dat', 'r') as f:\n" " reader = csv.reader(f, 'tab')\n" " for row in reader:\n" " if row[0][0]=='#': continue\n" " type = row[0]\n" " chr = row[1]\n" " if type=='DIST':\n" " if chr not in dat: dat[chr] = []\n" " dat[chr].append(row)\n" " elif type=='FIT':\n" " if chr not in fit: fit[chr] = []\n" " fit[chr].append(row)\n" " elif type=='CN':\n" " cn[chr] = row[2]\n" "\n" "def plot_dist(dat,fit,chr):\n" " fig, ax = plt.subplots(1, 1, figsize=(7,5))\n" " ax.plot([x[2] for x in dat[chr]],[x[3] for x in dat[chr]],'k-',label='Distribution')\n" " if chr in fit:\n" " for i in range(len(fit[chr])):\n" " pfit = fit[chr][i]\n" " exec('def xfit(x): return '+pfit[5])\n" " istart = int(pfit[3])\n" " iend = int(pfit[4])+1\n" " vals = dat[chr][istart:iend]\n" " args = {}\n" " if i==0: args = {'label':'Target to Fit'}\n" " ax.plot([x[2] for x in vals],[x[3] for x in vals],'r-',**args)\n" " if i==0: args = {'label':'Best Fit'}\n" " ax.plot([x[2] for x in vals],[xfit(float(x[2])) for x in vals],'g-',**args)\n" " ax.set_title('BAF distribution, chr'+chr)\n" " ax.set_xlabel('BAF')\n" " ax.set_ylabel('Frequency')\n" " ax.legend(loc='best',prop={'size':7},frameon=False)\n" " plt.savefig(outdir+'/dist.chr'+chr+'.png')\n" " plt.close()\n" "\n" "def plot_copy_number(cn):\n" " fig, ax = plt.subplots(1, 1, figsize=(7,5))\n" " xlabels = sorted(cn.keys())\n" " xvals = range(len(xlabels))\n" " yvals = [float(cn[x]) for x in xlabels]\n" " ax.plot(xvals,yvals,'o',color='red')\n" " for i in range(len(xvals)):\n" " if yvals[i]==-1: ax.annotate('?', xy=(xvals[i],0.5),va='center',ha='center',color='red',fontweight='bold')\n" " ax.tick_params(axis='both', which='major', labelsize=9)\n" " ax.set_xticks(xvals)\n" " ax.set_xticklabels(xlabels,rotation=45)\n" " ax.set_xlim(-1,len(xlabels))\n" " ax.set_ylim(0,5.0)\n" " ax.set_yticks([1.0,2.0,3.0,4.0])\n" " ax.set_xlabel('Chromosome')\n" " ax.set_ylabel('Copy Number')\n" " plt.savefig(outdir+'/copy-number.png')\n" " plt.close()\n" "\n" "class myParser(argparse.ArgumentParser):\n" " def error(self, message):\n" " self.print_help()\n" " sys.stderr.write('error: %%s\\n' %% message)\n" " sys.exit(2)\n" "\n" "def main():\n" " parser = myParser()\n" " parser.add_argument('-a', '--all', action='store_true', help='Create all plots')\n" " parser.add_argument('-c', '--copy-number', action='store_true', help='Create copy-number plot')\n" " parser.add_argument('-d', '--distrib', metavar='CHR', help='Plot BAF distribution of a single chromosome')\n" " args = parser.parse_args()\n" " dat = {}; fit = {}; cn = {}\n" " read_dat(dat,fit,cn)\n" " if args.distrib!=None:\n" " plot_dist(dat,fit,args.distrib)\n" " if args.all:\n" " for chr in dat: plot_dist(dat,fit,chr)\n" " plot_copy_number(cn)\n" " elif args.copy_number:\n" " plot_copy_number(cn)\n" " else:\n" " for chr in dat: plot_dist(dat,fit,chr)\n" "\n" "if __name__ == '__main__':\n" " main()\n", args->output_dir); //--------------------------------------- chmod(fname, S_IWUSR|S_IRUSR|S_IRGRP|S_IROTH|S_IXUSR|S_IXGRP|S_IXOTH); if ( fclose(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,fname); free(fname); } static void destroy_data(args_t *args) { int i; for (i=0; indist; i++) { free(args->dist[i].chr); free(args->dist[i].yvals); } free(args->dist); free(args->xvals); if ( fclose(args->dat_fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->dat_fname); free(args->dat_fname); } static void save_dist(args_t *args, dist_t *dist) { int i; for (i=0; inbins; i++) fprintf(args->dat_fp,"DIST\t%s\t%f\t%f\n",dist->chr,dist->xvals[i],dist->yvals[i]); } static void fit_curves(args_t *args) { peakfit_t *pkf = peakfit_init(); peakfit_verbose(pkf,args->verbose); int i, nmc = 50; for (i=0; indist; i++) { dist_t *dist = &args->dist[i]; save_dist(args, &args->dist[i]); if ( dist->copy_number!=0 ) { fprintf(args->dat_fp,"CN\t%s\t%.2f\n", dist->chr,(float)dist->copy_number); continue; } if ( args->verbose ) fprintf(stderr,"%s:\n", dist->chr); int nrr_aa = dist->iaa - dist->irr + 1; int nrr_ra = dist->ira - dist->irr + 1; int naa_max = dist->nvals - dist->iaa; double xrr = dist->xvals[dist->irr], *xrr_vals = &dist->xvals[dist->irr], *yrr_vals = &dist->yvals[dist->irr]; double xaa = dist->xvals[dist->iaa], *xaa_vals = &dist->xvals[dist->iaa], *yaa_vals = &dist->yvals[dist->iaa]; double xra = dist->xvals[dist->ira]; double xmax = dist->xvals[dist->nvals-1]; // CN2 double cn2aa_fit = 0, cn2ra_fit, cn2_fit; char *cn2aa_func = 0, *cn2ra_func; double cn2aa_params[3] = {1,1,1} ,cn2ra_params[3]; if ( args->include_aa ) { peakfit_reset(pkf); peakfit_add_exp(pkf, 1.0,1.0,0.2, 5); peakfit_set_mc(pkf, 0.01,0.3,2,nmc); peakfit_set_mc(pkf, 0.05,1.0,0,nmc); cn2aa_fit = peakfit_run(pkf, naa_max, xaa_vals, yaa_vals); cn2aa_func = strdup(peakfit_sprint_func(pkf)); peakfit_get_params(pkf,0,cn2aa_params,3); } peakfit_reset(pkf); peakfit_add_bounded_gaussian(pkf, 1.0,0.5,0.03, 0.45,0.55, 7); peakfit_set_mc(pkf, 0.01,0.3,2,nmc); peakfit_set_mc(pkf, 0.05,1.0,0,nmc); cn2ra_fit = peakfit_run(pkf, nrr_aa,xrr_vals,yrr_vals); cn2ra_func = strdup(peakfit_sprint_func(pkf)); cn2_fit = cn2ra_fit + cn2aa_fit; peakfit_get_params(pkf,0,cn2ra_params,3); // CN3: fit two peaks, then enforce the symmetry and fit again double cn3rra_params[5], cn3raa_params[5], *cn3aa_params = cn2aa_params; double cn3aa_fit = cn2aa_fit, cn3ra_fit; char *cn3aa_func = cn2aa_func, *cn3ra_func; double min_dx3 = 0.5 - 1./(args->min_fraction+2); peakfit_reset(pkf); peakfit_add_bounded_gaussian(pkf, 1.0,1/3.,0.03, xrr,xra-min_dx3, 7); peakfit_set_mc(pkf, xrr,xra-min_dx3, 1,nmc); peakfit_add_bounded_gaussian(pkf, 1.0,2/3.,0.03, xra+min_dx3,xaa, 7); peakfit_set_mc(pkf, xra+min_dx3,xaa, 1,nmc); peakfit_run(pkf, nrr_aa, xrr_vals, yrr_vals); // force symmetry around x=0.5 peakfit_get_params(pkf,0,cn3rra_params,5); peakfit_get_params(pkf,1,cn3raa_params,5); double cn3_dx = (0.5-cn3rra_params[1] + cn3raa_params[1]-0.5)*0.5; if ( cn3_dx > 0.5/3 ) cn3_dx = 0.5/3; // CN3 peaks should not be separated by more than 1/3 peakfit_reset(pkf); peakfit_add_gaussian(pkf, cn3rra_params[0],0.5-cn3_dx,cn3rra_params[2], 5); peakfit_add_gaussian(pkf, cn3raa_params[0],0.5+cn3_dx,cn3raa_params[2], 5); cn3ra_fit = peakfit_run(pkf, nrr_aa, xrr_vals, yrr_vals); cn3ra_func = strdup(peakfit_sprint_func(pkf)); // compare peak sizes peakfit_get_params(pkf,0,cn3rra_params,3); peakfit_get_params(pkf,1,cn3raa_params,3); double cn3rra_size = cn3rra_params[0]*cn3rra_params[0]; double cn3raa_size = cn3raa_params[0]*cn3raa_params[0]; double cn3_dy = cn3rra_size > cn3raa_size ? cn3raa_size/cn3rra_size : cn3rra_size/cn3raa_size; double cn3_frac = (1 - 2*cn3rra_params[1]) / cn3rra_params[1]; double cn3_fit = cn3ra_fit + cn3aa_fit; // A very reasonable heuristics: check if the peak's width converged, exclude far too broad or far too narrow peaks if ( cn3rra_params[2]>0.3 || cn3raa_params[2]>0.3 ) cn3_fit = HUGE_VAL; if ( cn3rra_params[2]<1e-2 || cn3raa_params[2]<1e-2 ) cn3_fit = HUGE_VAL; // CN4 (contaminations) // - first fit only the [0,0.5] part of the data, then enforce the symmetry and fit again // - min_frac=1 (resp. 0.5) is interpreted as 50:50% (rep. 75:25%) contamination double cn4AAaa_params[3] = {1,1,1} ,cn4AAra_params[3] = {1,1,1}, cn4RAra_params[3], cn4RArr_params[5], cn4RAaa_params[5]; double cn4aa_fit = 0, cn4ra_fit; char *cn4aa_func = 0, *cn4ra_func; double min_dx4 = 0.25*args->min_fraction; if ( args->include_aa ) { peakfit_reset(pkf); peakfit_add_exp(pkf, 0.5,1.0,0.2, 5); peakfit_set_mc(pkf, 0.01,0.3,2,nmc); peakfit_add_bounded_gaussian(pkf, 0.4,(xaa+xmax)*0.5,2e-2, xaa,xmax, 7); peakfit_set_mc(pkf, xaa,xmax, 1,nmc); cn4aa_fit = peakfit_run(pkf, naa_max, xaa_vals,yaa_vals); cn4aa_func = strdup(peakfit_sprint_func(pkf)); peakfit_get_params(pkf,0,cn4AAaa_params,3); peakfit_get_params(pkf,1,cn4AAra_params,5); } peakfit_reset(pkf); // first fit only the [0,0.5] part of the data peakfit_add_gaussian(pkf, 1.0,0.5,0.03, 5); peakfit_add_bounded_gaussian(pkf, 0.6,0.3,0.03, xrr,xra-min_dx4, 7); peakfit_set_mc(pkf, xrr,xra-min_dx4,2,nmc); peakfit_run(pkf, nrr_ra , xrr_vals, yrr_vals); // now forcet symmetry around x=0.5 peakfit_get_params(pkf,0,cn4RAra_params,3); peakfit_get_params(pkf,1,cn4RArr_params,5); double cn4_dx = 0.5-cn4RArr_params[1]; if ( cn4_dx > 0.25 ) cn4_dx = 0.25; // CN4 peaks should not be separated by more than 0.5 peakfit_reset(pkf); peakfit_add_gaussian(pkf, cn4RAra_params[0],0.5,cn4RAra_params[2], 5); peakfit_add_gaussian(pkf, cn4RArr_params[0],0.5-cn4_dx,cn4RArr_params[2], 5); peakfit_add_gaussian(pkf, cn4RArr_params[0],0.5+cn4_dx,cn4RArr_params[2], 5); peakfit_set_mc(pkf, 0.1,cn4RAra_params[0],0,nmc); peakfit_set_mc(pkf, 0.01,0.1,2,nmc); cn4ra_fit = peakfit_run(pkf, nrr_aa , xrr_vals, yrr_vals); cn4ra_func = strdup(peakfit_sprint_func(pkf)); peakfit_get_params(pkf,0,cn4RAra_params,3); peakfit_get_params(pkf,1,cn4RArr_params,3); peakfit_get_params(pkf,2,cn4RAaa_params,3); double cn4RAra_size = cn4RAra_params[0]==0 ? HUGE_VAL : cn4RAra_params[0]*cn4RAra_params[0]; double cn4RArr_size = cn4RArr_params[0]*cn4RArr_params[0]; double cn4RAaa_size = cn4RAaa_params[0]*cn4RAaa_params[0]; double cn4RArr_dy = cn4RArr_size < cn4RAra_size ? cn4RArr_size/cn4RAra_size : cn4RAra_size/cn4RArr_size; double cn4RAaa_dy = cn4RAaa_size < cn4RAra_size ? cn4RAaa_size/cn4RAra_size : cn4RAra_size/cn4RAaa_size; double cn4_dy = cn4RArr_dy < cn4RAaa_dy ? cn4RArr_dy/cn4RAaa_dy : cn4RAaa_dy/cn4RArr_dy; double cn4_ymin = cn4RArr_size < cn4RAaa_size ? cn4RArr_size/cn4RAra_size : cn4RAaa_size/cn4RAra_size; cn4_dx = (cn4RAaa_params[1]-0.5) - (0.5-cn4RArr_params[1]); double cn4_frac = cn4RAaa_params[1] - cn4RArr_params[1]; double cn4_fit = cn4ra_fit + cn4aa_fit; // A very reasonable heuristics: check if the peak's width converged, exclude far too broad or far too narrow peaks if ( cn4RAra_params[2]>0.3 || cn4RArr_params[2]>0.3 || cn4RAaa_params[2]>0.3 ) cn4_fit = HUGE_VAL; if ( cn4RAra_params[2]<1e-2 || cn4RArr_params[2]<1e-2 || cn4RAaa_params[2]<1e-2 ) cn4_fit = HUGE_VAL; // Choose the best match char cn2_fail = '*', cn3_fail = '*', cn4_fail = '*'; if ( cn2_fit > args->fit_th ) cn2_fail = 'f'; if ( cn3_fit > args->fit_th ) cn3_fail = 'f'; else if ( cn3_dy < args->peak_symmetry ) cn3_fail = 'y'; // size difference is too big if ( cn4_fit > args->fit_th ) cn4_fail = 'f'; else if ( cn4_ymin < args->min_peak_size ) cn4_fail = 'y'; // side peak is too small else if ( cn4_dy < args->peak_symmetry ) cn4_fail = 'Y'; // size difference is too big else if ( cn4_dx > 0.1 ) cn4_fail = 'x'; // side peaks placed assymetrically double cn = -1, fit = cn2_fit; if ( cn2_fail == '*' ) { cn = 2; fit = cn2_fit; } if ( cn3_fail == '*' ) { // Use cn_penalty as a tiebreaker. If set to 0.3, cn3_fit must be 30% smaller than cn2_fit. if ( cn<0 || cn3_fit < (1-args->cn_penalty) * fit ) { cn = 2 + cn3_frac; fit = cn3_fit; if ( cn2_fail=='*' ) cn2_fail = 'p'; } else cn3_fail = 'p'; } if ( cn4_fail == '*' ) { if ( cn<0 || cn4_fit < (1-args->cn_penalty) * fit ) { cn = 3 + cn4_frac; fit = cn4_fit; if ( cn2_fail=='*' ) cn2_fail = 'p'; if ( cn3_fail=='*' ) cn3_fail = 'p'; } else cn4_fail = 'p'; } if ( args->verbose ) { fprintf(stderr,"\tcn2 %c fit=%e\n", cn2_fail, cn2_fit); fprintf(stderr,"\t .. %e\n", cn2ra_fit); fprintf(stderr,"\t RA: %f %f %f\n", cn2ra_params[0],cn2ra_params[1],cn2ra_params[2]); fprintf(stderr,"\t .. %e\n", cn2aa_fit); fprintf(stderr,"\t AA: %f %f %f\n", cn2aa_params[0],cn2aa_params[1],cn2aa_params[2]); fprintf(stderr,"\t func:\n"); fprintf(stderr,"\t %s\n", cn2ra_func); fprintf(stderr,"\t %s\n", cn2aa_func); fprintf(stderr,"\n"); fprintf(stderr,"\tcn3 %c fit=%e frac=%f symmetry=%f\n", cn3_fail, cn3_fit, cn3_frac, cn3_dy); fprintf(stderr,"\t .. %e\n", cn3ra_fit); fprintf(stderr,"\t RRA: %f %f %f\n", cn3rra_params[0],cn3rra_params[1],cn3rra_params[2]); fprintf(stderr,"\t RAA: %f %f %f\n", cn3raa_params[0],cn3raa_params[1],cn3raa_params[2]); fprintf(stderr,"\t .. %e\n", cn3aa_fit); fprintf(stderr,"\t AAA: %f %f %f\n", cn3aa_params[0],cn3aa_params[1],cn3aa_params[2]); fprintf(stderr,"\t func:\n"); fprintf(stderr,"\t %s\n", cn3ra_func); fprintf(stderr,"\t %s\n", cn3aa_func); fprintf(stderr,"\n"); fprintf(stderr,"\tcn4 %c fit=%e frac=%f symmetry=%f ymin=%f\n", cn4_fail, cn4_fit, cn4_frac, cn4_dy, cn4_ymin); fprintf(stderr,"\t .. %e\n", cn4ra_fit); fprintf(stderr,"\t RArr: %f %f %f\n", cn4RArr_params[0],cn4RArr_params[1],cn4RArr_params[2]); fprintf(stderr,"\t RAra: %f %f %f\n", cn4RAra_params[0],cn4RAra_params[1],cn4RAra_params[2]); fprintf(stderr,"\t RAaa: %f %f %f\n", cn4RAaa_params[0],cn4RAaa_params[1],cn4RAaa_params[2]); fprintf(stderr,"\t .. %e\n", cn4aa_fit); fprintf(stderr,"\t AAaa: %f %f %f\n", cn4AAaa_params[0],cn4AAaa_params[1],cn4AAaa_params[2]); fprintf(stderr,"\t func:\n"); fprintf(stderr,"\t %s\n", cn4ra_func); fprintf(stderr,"\t %s\n", cn4aa_func); fprintf(stderr,"\n"); } if ( args->force_cn==2 || cn2_fail == '*' ) { fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn2ra_fit,dist->irr,dist->iaa,cn2ra_func); if ( cn2aa_func ) fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn2aa_fit,dist->iaa,dist->nvals-1,cn2aa_func); } if ( args->force_cn==3 || cn3_fail == '*' ) { fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn3ra_fit,dist->irr,dist->iaa,cn3ra_func); if ( cn3aa_func ) fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn3aa_fit,dist->iaa,dist->nvals-1,cn3aa_func); } if ( args->force_cn==4 || cn4_fail == '*' ) { fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn4ra_fit,dist->irr,dist->iaa,cn4ra_func); if ( cn4aa_func ) fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn4aa_fit,dist->iaa,dist->nvals-1,cn4aa_func); } fprintf(args->dat_fp,"CN\t%s\t%.2f\t%f\n", dist->chr, cn, fit); free(cn2aa_func); free(cn2ra_func); free(cn3ra_func); free(cn4ra_func); free(cn4aa_func); } peakfit_destroy(pkf); } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Detect number of chromosomal copies from Illumina's B-allele frequency (BAF)\n"); fprintf(stderr, "Usage: bcftools polysomy [OPTIONS] FILE.vcf\n"); fprintf(stderr, "\n"); fprintf(stderr, "General options:\n"); fprintf(stderr, " -o, --output-dir PATH \n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --sample NAME Sample to analyze\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " -v, --verbose \n"); fprintf(stderr, "\n"); fprintf(stderr, "Algorithm options:\n"); fprintf(stderr, " -b, --peak-size FLOAT Minimum peak size (0-1, larger is stricter) [0.1]\n"); fprintf(stderr, " -c, --cn-penalty FLOA> Penalty for increasing CN (0-1, larger is stricter) [0.7]\n"); fprintf(stderr, " -f, --fit-th FLOAT Goodness of fit threshold (>0, smaller is stricter) [3.3]\n"); fprintf(stderr, " -i, --include-aa Include the AA peak in CN2 and CN3 evaluation\n"); fprintf(stderr, " -m, --min-fraction FLOAT Minimum distinguishable fraction of aberrant cells [0.1]\n"); fprintf(stderr, " -p, --peak-symmetry FLOAT Peak symmetry threshold (0-1, larger is stricter) [0.5]\n"); fprintf(stderr, "\n"); exit(1); } int main_polysomy(int argc, char *argv[]) { args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->nbins = 150; args->fit_th = 3.3; args->cn_penalty = 0.7; args->peak_symmetry = 0.5; args->min_peak_size = 0.1; args->ra_rr_scaling = 1; args->min_fraction = 0.1; args->smooth = -3; args->regions_overlap = 1; args->targets_overlap = 0; static struct option loptions[] = { {"ra-rr-scaling",0,0,1}, // hidden option {"force-cn",1,0,2}, // hidden option {"smooth",1,0,'S'}, // hidden option {"nbins",1,0,'n'}, // hidden option {"include-aa",0,0,'i'}, {"peak-size",1,0,'b'}, {"min-fraction",1,0,'m'}, {"verbose",0,0,'v'}, {"fit-th",1,0,'f'}, {"cn-penalty",1,0,'c'}, {"peak-symmetry",1,0,'p'}, {"output-dir",1,0,'o'}, {"sample",1,0,'s'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,4}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,3}, {0,0,0,0} }; char *tmp; int c; while ((c = getopt_long(argc, argv, "h?o:vt:T:r:R:s:f:p:c:im:b:n:S:",loptions,NULL)) >= 0) { switch (c) { case 1 : args->ra_rr_scaling = 0; break; case 2 : args->force_cn = atoi(optarg); break; case 3 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'n': args->nbins = atoi(optarg); break; case 'S': args->smooth = atoi(optarg); break; case 'i': args->include_aa = 1; break; case 'b': args->min_peak_size = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -b %s\n", optarg); if ( args->min_peak_size<0 || args->min_peak_size>1 ) error("Range error: -b %s\n", optarg); break; case 'm': args->min_fraction = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -n %s\n", optarg); if ( args->min_fraction<0 || args->min_fraction>1 ) error("Range error: -n %s\n", optarg); break; case 'f': args->fit_th = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -f %s\n", optarg); break; case 'p': args->peak_symmetry = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -p %s\n", optarg); break; case 'c': args->cn_penalty = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -c %s\n", optarg); break; case 's': args->sample = optarg; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; args->targets_is_file = 1; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; case 'o': args->output_dir = optarg; break; case 'v': args->verbose++; break; default: usage(args); break; } } if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; } else args->fname = argv[optind]; if ( !args->fname ) usage(args); if ( !args->output_dir ) error("Missing the -o option\n"); init_data(args); fit_curves(args); destroy_data(args); free(args); return 0; } bcftools-1.21/prob1.c000066400000000000000000000474631467060157400144670ustar00rootroot00000000000000/* prob1.c -- mathematical utility functions. Copyright (C) 2010, 2011 Broad Institute. Copyright (C) 2012, 2013-2014, 2017 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include "prob1.h" #define MC_MAX_EM_ITER 16 #define MC_EM_EPS 1e-5 #define MC_DEF_INDEL 0.15 void bcf_p1_indel_prior(bcf_p1aux_t *ma, double x) { int i; for (i = 0; i < ma->M; ++i) ma->phi_indel[i] = ma->phi[i] * x; ma->phi_indel[ma->M] = 1. - ma->phi[ma->M] * x; } static void init_prior(int type, double theta, int M, double *phi) { int i; if (type == MC_PTYPE_COND2) { for (i = 0; i <= M; ++i) phi[i] = 2. * (i + 1) / (M + 1) / (M + 2); } else if (type == MC_PTYPE_FLAT) { for (i = 0; i <= M; ++i) phi[i] = 1. / (M + 1); } else { double sum; for (i = 0, sum = 0.; i < M; ++i) sum += (phi[i] = theta / (M - i)); phi[M] = 1. - sum; } } void bcf_p1_init_prior(bcf_p1aux_t *ma, int type, double theta) { init_prior(type, theta, ma->M, ma->phi); bcf_p1_indel_prior(ma, MC_DEF_INDEL); } void bcf_p1_init_subprior(bcf_p1aux_t *ma, int type, double theta) { if (ma->n1 <= 0 || ma->n1 >= ma->M) return; init_prior(type, theta, 2*ma->n1, ma->phi1); init_prior(type, theta, 2*(ma->n - ma->n1), ma->phi2); } /* Initialise a bcf_p1aux_t */ bcf_p1aux_t *bcf_p1_init(int n_smpl, uint8_t *ploidy) { bcf_p1aux_t *ma; int i; ma = (bcf_p1aux_t*) calloc(1, sizeof(bcf_p1aux_t)); ma->n1 = -1; ma->n = n_smpl; ma->M = 2 * n_smpl; if (ploidy) { ma->ploidy = (uint8_t*) malloc(n_smpl); memcpy(ma->ploidy, ploidy, n_smpl); for (i = 0, ma->M = 0; i < n_smpl; ++i) ma->M += ploidy[i]; if (ma->M == 2 * n_smpl) { free(ma->ploidy); ma->ploidy = 0; } } ma->q2p = (double*) calloc(256, sizeof(double)); ma->pdg = (double*) calloc(3 * ma->n, sizeof(double)); ma->phi = (double*) calloc(ma->M + 1, sizeof(double)); ma->phi_indel = (double*) calloc(ma->M + 1, sizeof(double)); ma->phi1 = (double*) calloc(ma->M + 1, sizeof(double)); ma->phi2 = (double*) calloc(ma->M + 1, sizeof(double)); ma->z = (double*) calloc(ma->M + 1, sizeof(double)); ma->zswap = (double*) calloc(ma->M + 1, sizeof(double)); ma->z1 = (double*) calloc(ma->M + 1, sizeof(double)); // actually we do not need this large ma->z2 = (double*) calloc(ma->M + 1, sizeof(double)); ma->afs = (double*) calloc(ma->M + 1, sizeof(double)); ma->afs1 = (double*) calloc(ma->M + 1, sizeof(double)); ma->lf = (double*) calloc(ma->M + 1, sizeof(double)); for (i = 0; i < 256; ++i) ma->q2p[i] = pow(10., -i / 10.); for (i = 0; i <= ma->M; ++i) ma->lf[i] = lgamma(i + 1); bcf_p1_init_prior(ma, MC_PTYPE_FULL, 1e-3); // the simplest prior return ma; } int bcf_p1_get_M(bcf_p1aux_t *b) { return b->M; } int bcf_p1_set_n1(bcf_p1aux_t *b, int n1) { if (n1 == 0 || n1 >= b->n) return -1; if (b->M != b->n * 2) { fprintf(stderr, "[%s] unable to set `n1' when there are haploid samples.\n", __func__); return -1; } b->n1 = n1; return 0; } void bcf_p1_destroy(bcf_p1aux_t *ma) { if (ma) { int k; free(ma->lf); if (ma->hg && ma->n1 > 0) { for (k = 0; k <= 2*ma->n1; ++k) free(ma->hg[k]); free(ma->hg); } free(ma->ploidy); free(ma->q2p); free(ma->pdg); free(ma->phi); free(ma->phi_indel); free(ma->phi1); free(ma->phi2); free(ma->z); free(ma->zswap); free(ma->z1); free(ma->z2); free(ma->afs); free(ma->afs1); free(ma); } } extern double kf_gammap(double s, double z); int test16(bcf1_t *b, anno16_t *a); /* Calculate P(D|g) */ static int cal_pdg(const bcf1_t *b, bcf_p1aux_t *ma) { int i, j; long p_a[16], *p=p_a, tmp; if (b->n_allele > 16) p = (long*) malloc(b->n_allele * sizeof(long)); memset(p, 0, sizeof(long) * b->n_allele); // Set P(D|g) for each sample and sum phread likelihoods across all samples to create lk for (j = 0; j < ma->n; ++j) { // Fetch the PL array for the sample const int *pi = ma->PL + j * ma->PL_len; // Fetch the P(D|g) array for the sample double *pdg = ma->pdg + j * 3; pdg[0] = ma->q2p[pi[2]]; pdg[1] = ma->q2p[pi[1]]; pdg[2] = ma->q2p[pi[0]]; for (i = 0; i < b->n_allele; ++i) p[i] += (int)pi[(i+1)*(i+2)/2-1]; } for (i = 0; i < b->n_allele; ++i) p[i] = p[i]<<4 | i; for (i = 1; i < b->n_allele; ++i) // insertion sort for (j = i; j > 0 && p[j] < p[j-1]; --j) tmp = p[j], p[j] = p[j-1], p[j-1] = tmp; for (i = b->n_allele - 1; i >= 0; --i) if ((p[i]&0xf) == 0) break; if (p != p_a) free(p); return i; } /* f0 is freq of the ref allele */ int bcf_p1_call_gt(const bcf_p1aux_t *ma, double f0, int k, int is_var) { double sum, g[3]; double max, f3[3], *pdg = ma->pdg + k * 3; int q, i, max_i, ploidy; /* determine ploidy */ ploidy = ma->ploidy? ma->ploidy[k] : 2; if (ploidy == 2) { /* given allele frequency we can determine how many of each * genotype we have by HWE p=1-q PP=p^2 PQ&QP=2*p*q QQ=q^2 */ f3[0] = (1.-f0)*(1.-f0); f3[1] = 2.*f0*(1.-f0); f3[2] = f0*f0; } else { f3[0] = 1. - f0; f3[1] = 0; f3[2] = f0; } for (i = 0, sum = 0.; i < 3; ++i) sum += (g[i] = pdg[i] * f3[i]); /* normalise g and then determine max */ for (i = 0, max = -1., max_i = 0; i < 3; ++i) { g[i] /= sum; if (g[i] > max) max = g[i], max_i = i; } if ( !is_var ) { max_i = 2; max = g[2]; } // force 0/0 genotype if the site is non-variant max = 1. - max; if (max < 1e-308) max = 1e-308; q = (int)(-4.343 * log(max) + .499); if (q > 99) q = 99; return q<<2|max_i; } // If likelihoods fall below this they get squashed to 0 #define TINY 1e-20 static void mc_cal_y_core(bcf_p1aux_t *ma, int beg) { double *z[2], *tmp, *pdg; int _j, last_min, last_max; assert(beg == 0 || ma->M == ma->n*2); z[0] = ma->z; z[1] = ma->zswap; pdg = ma->pdg; memset(z[0], 0, sizeof(double) * (ma->M + 1)); memset(z[1], 0, sizeof(double) * (ma->M + 1)); z[0][0] = 1.; last_min = last_max = 0; ma->t = 0.; if (ma->M == ma->n * 2) { int M = 0; for (_j = beg; _j < ma->n; ++_j) { int k, j = _j - beg, _min = last_min, _max = last_max, M0; double p[3], sum; M0 = M; M += 2; // Fetch P(D|g) for this sample pdg = ma->pdg + _j * 3; p[0] = pdg[0]; p[1] = 2. * pdg[1]; p[2] = pdg[2]; for (; _min < _max && z[0][_min] < TINY; ++_min) z[0][_min] = z[1][_min] = 0.; for (; _max > _min && z[0][_max] < TINY; --_max) z[0][_max] = z[1][_max] = 0.; _max += 2; if (_min == 0) k = 0, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k]; if (_min <= 1) k = 1, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1]; for (k = _min < 2? 2 : _min; k <= _max; ++k) z[1][k] = (M0-k+1)*(M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1] + k*(k-1)* p[2] * z[0][k-2]; for (k = _min, sum = 0.; k <= _max; ++k) sum += z[1][k]; ma->t += log(sum / (M * (M - 1.))); for (k = _min; k <= _max; ++k) z[1][k] /= sum; if (_min >= 1) z[1][_min-1] = 0.; if (_min >= 2) z[1][_min-2] = 0.; // If we are not on the last sample if (j < ma->n - 1) z[1][_max+1] = z[1][_max+2] = 0.; if (_j == ma->n1 - 1) { // set pop1; ma->n1==-1 when unset ma->t1 = ma->t; memcpy(ma->z1, z[1], sizeof(double) * (ma->n1 * 2 + 1)); } tmp = z[0]; z[0] = z[1]; z[1] = tmp; last_min = _min; last_max = _max; } //for (_j = 0; _j < last_min; ++_j) z[0][_j] = 0.; // TODO: are these necessary? //for (_j = last_max + 1; _j < ma->M; ++_j) z[0][_j] = 0.; } else { // this block is very similar to the block above; these two might be merged in future int j, M = 0; for (j = 0; j < ma->n; ++j) { int k, M0, _min = last_min, _max = last_max; double p[3], sum; // Fetch P(D|g) for this sample pdg = ma->pdg + j * 3; for (; _min < _max && z[0][_min] < TINY; ++_min) z[0][_min] = z[1][_min] = 0.; for (; _max > _min && z[0][_max] < TINY; --_max) z[0][_max] = z[1][_max] = 0.; M0 = M; M += ma->ploidy[j]; if (ma->ploidy[j] == 1) { p[0] = pdg[0]; p[1] = pdg[2]; _max++; if (_min == 0) k = 0, z[1][k] = (M0+1-k) * p[0] * z[0][k]; for (k = _min < 1? 1 : _min; k <= _max; ++k) z[1][k] = (M0+1-k) * p[0] * z[0][k] + k * p[1] * z[0][k-1]; for (k = _min, sum = 0.; k <= _max; ++k) sum += z[1][k]; ma->t += log(sum / M); for (k = _min; k <= _max; ++k) z[1][k] /= sum; if (_min >= 1) z[1][_min-1] = 0.; // If we are not on the last sample if (j < ma->n - 1) z[1][_max+1] = 0.; } else if (ma->ploidy[j] == 2) { p[0] = pdg[0]; p[1] = 2 * pdg[1]; p[2] = pdg[2]; _max += 2; if (_min == 0) k = 0, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k]; if (_min <= 1) k = 1, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1]; for (k = _min < 2? 2 : _min; k <= _max; ++k) z[1][k] = (M0-k+1)*(M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1] + k*(k-1)* p[2] * z[0][k-2]; for (k = _min, sum = 0.; k <= _max; ++k) sum += z[1][k]; ma->t += log(sum / (M * (M - 1.))); for (k = _min; k <= _max; ++k) z[1][k] /= sum; if (_min >= 1) z[1][_min-1] = 0.; if (_min >= 2) z[1][_min-2] = 0.; // If we are not on the last sample if (j < ma->n - 1) z[1][_max+1] = z[1][_max+2] = 0.; } tmp = z[0]; z[0] = z[1]; z[1] = tmp; last_min = _min; last_max = _max; } } if (z[0] != ma->z) memcpy(ma->z, z[0], sizeof(double) * (ma->M + 1)); } static void mc_cal_y(bcf_p1aux_t *ma) { if (ma->n1 > 0 && ma->n1 < ma->n && ma->M == ma->n * 2) { // NB: ma->n1 is ineffective when there are haploid samples int k; long double x; memset(ma->z1, 0, sizeof(double) * (2 * ma->n1 + 1)); memset(ma->z2, 0, sizeof(double) * (2 * (ma->n - ma->n1) + 1)); ma->t1 = ma->t2 = 0.; mc_cal_y_core(ma, ma->n1); ma->t2 = ma->t; memcpy(ma->z2, ma->z, sizeof(double) * (2 * (ma->n - ma->n1) + 1)); mc_cal_y_core(ma, 0); // rescale z x = expl(ma->t - (ma->t1 + ma->t2)); for (k = 0; k <= ma->M; ++k) ma->z[k] *= x; } else mc_cal_y_core(ma, 0); } #define CONTRAST_TINY 1e-30 extern double kf_gammaq(double s, double z); // incomplete gamma function for chi^2 test static inline double chi2_test(int a, int b, int c, int d) { double x, z; x = (double)(a+b) * (c+d) * (b+d) * (a+c); if (x == 0.) return 1; z = a * d - b * c; return kf_gammaq(.5, .5 * z * z * (a+b+c+d) / x); } // chi2=(a+b+c+d)(ad-bc)^2/[(a+b)(c+d)(a+c)(b+d)] static inline double contrast2_aux(const bcf_p1aux_t *p1, double sum, int k1, int k2, double x[3]) { double p = p1->phi[k1+k2] * p1->z1[k1] * p1->z2[k2] / sum * p1->hg[k1][k2]; int n1 = p1->n1, n2 = p1->n - p1->n1; if (p < CONTRAST_TINY) return -1; if (.5*k1/n1 < .5*k2/n2) x[1] += p; else if (.5*k1/n1 > .5*k2/n2) x[2] += p; else x[0] += p; return p * chi2_test(k1, k2, (n1<<1) - k1, (n2<<1) - k2); } static double contrast2(bcf_p1aux_t *p1, double ret[3]) { int k, k1, k2, k10, k20, n1, n2; double sum; // get n1 and n2 n1 = p1->n1; n2 = p1->n - p1->n1; if (n1 <= 0 || n2 <= 0) return 0.; if (p1->hg == 0) { // initialize the hypergeometric distribution /* NB: the hg matrix may take a lot of memory when there are many samples. There is a way to avoid precomputing this matrix, but it is slower and quite intricate. The following computation in this block can be accelerated with a similar strategy, but perhaps this is not a serious concern for now. */ double tmp = lgamma(2*(n1+n2)+1) - (lgamma(2*n1+1) + lgamma(2*n2+1)); p1->hg = (double**) calloc(2*n1+1, sizeof(double*)); for (k1 = 0; k1 <= 2*n1; ++k1) { p1->hg[k1] = (double*)calloc(2*n2+1, sizeof(double)); for (k2 = 0; k2 <= 2*n2; ++k2) p1->hg[k1][k2] = exp(lgamma(k1+k2+1) + lgamma(p1->M-k1-k2+1) - (lgamma(k1+1) + lgamma(k2+1) + lgamma(2*n1-k1+1) + lgamma(2*n2-k2+1) + tmp)); } } { // compute long double suml = 0; for (k = 0; k <= p1->M; ++k) suml += p1->phi[k] * p1->z[k]; sum = suml; } { // get the max k1 and k2 double max; int max_k; for (k = 0, max = 0, max_k = -1; k <= 2*n1; ++k) { double x = p1->phi1[k] * p1->z1[k]; if (x > max) max = x, max_k = k; } k10 = max_k; for (k = 0, max = 0, max_k = -1; k <= 2*n2; ++k) { double x = p1->phi2[k] * p1->z2[k]; if (x > max) max = x, max_k = k; } k20 = max_k; } { // We can do the following with one nested loop, but that is an O(N^2) thing. The following code block is much faster for large N. double x[3], y; long double z = 0., L[2]; x[0] = x[1] = x[2] = 0; L[0] = L[1] = 0; for (k1 = k10; k1 >= 0; --k1) { for (k2 = k20; k2 >= 0; --k2) { if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; else z += y; } for (k2 = k20 + 1; k2 <= 2*n2; ++k2) { if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; else z += y; } } ret[0] = x[0]; ret[1] = x[1]; ret[2] = x[2]; x[0] = x[1] = x[2] = 0; for (k1 = k10 + 1; k1 <= 2*n1; ++k1) { for (k2 = k20; k2 >= 0; --k2) { if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; else z += y; } for (k2 = k20 + 1; k2 <= 2*n2; ++k2) { if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; else z += y; } } ret[0] += x[0]; ret[1] += x[1]; ret[2] += x[2]; if (ret[0] + ret[1] + ret[2] < 0.95) { // in case of bad things happened ret[0] = ret[1] = ret[2] = 0; L[0] = L[1] = 0; for (k1 = 0, z = 0.; k1 <= 2*n1; ++k1) for (k2 = 0; k2 <= 2*n2; ++k2) if ((y = contrast2_aux(p1, sum, k1, k2, ret)) >= 0) z += y; if (ret[0] + ret[1] + ret[2] < 0.95) // It seems that this may be caused by floating point errors. I do not really understand why... z = 1.0, ret[0] = ret[1] = ret[2] = 1./3; } return (double)z; } } static double mc_cal_afs(bcf_p1aux_t *ma, double *p_ref_folded, double *p_var_folded) { int k; long double sum = 0., sum2; double *phi = ma->is_indel? ma->phi_indel : ma->phi; memset(ma->afs1, 0, sizeof(double) * (ma->M + 1)); mc_cal_y(ma); // compute AFS // MP15: is this using equation 20 from doi:10.1093/bioinformatics/btr509? for (k = 0, sum = 0.; k <= ma->M; ++k) sum += (long double)phi[k] * ma->z[k]; for (k = 0; k <= ma->M; ++k) { ma->afs1[k] = phi[k] * ma->z[k] / sum; if (isnan(ma->afs1[k]) || isinf(ma->afs1[k])) return -1.; } // compute folded variant probability for (k = 0, sum = 0.; k <= ma->M; ++k) sum += (long double)(phi[k] + phi[ma->M - k]) / 2. * ma->z[k]; for (k = 1, sum2 = 0.; k < ma->M; ++k) sum2 += (long double)(phi[k] + phi[ma->M - k]) / 2. * ma->z[k]; *p_var_folded = sum2 / sum; *p_ref_folded = (phi[k] + phi[ma->M - k]) / 2. * (ma->z[ma->M] + ma->z[0]) / sum; // the expected frequency for (k = 0, sum = 0.; k <= ma->M; ++k) { ma->afs[k] += ma->afs1[k]; sum += k * ma->afs1[k]; } return sum / ma->M; } int bcf_p1_cal(call_t *call, bcf1_t *b, int do_contrast, bcf_p1aux_t *ma, bcf_p1rst_t *rst) { int i, k; long double sum = 0.; ma->is_indel = bcf_is_snp(b) ? 0 : 1; rst->perm_rank = -1; ma->PL = call->PLs; ma->PL_len = call->nPLs / b->n_sample; if (b->n_allele < 2) return -1; // FIXME: find a better solution rst->rank0 = cal_pdg(b, ma); rst->f_exp = mc_cal_afs(ma, &rst->p_ref_folded, &rst->p_var_folded); rst->p_ref = ma->afs1[ma->M]; for (k = 0, sum = 0.; k < ma->M; ++k) sum += ma->afs1[k]; rst->p_var = (double)sum; { // compute the allele count double max = -1; rst->ac = -1; for (k = 0; k <= ma->M; ++k) if (max < ma->z[k]) max = ma->z[k], rst->ac = k; rst->ac = ma->M - rst->ac; } // calculate f_flat and f_em for (k = 0, sum = 0.; k <= ma->M; ++k) sum += (long double)ma->z[k]; rst->f_flat = 0.; for (k = 0; k <= ma->M; ++k) { double p = ma->z[k] / sum; rst->f_flat += k * p; } rst->f_flat /= ma->M; { // estimate equal-tail credible interval (95% level) int l, h; double p; for (i = 0, p = 0.; i <= ma->M; ++i) if (p + ma->afs1[i] > 0.025) break; else p += ma->afs1[i]; l = i; for (i = ma->M, p = 0.; i >= 0; --i) if (p + ma->afs1[i] > 0.025) break; else p += ma->afs1[i]; h = i; rst->cil = (double)(ma->M - h) / ma->M; rst->cih = (double)(ma->M - l) / ma->M; } if (ma->n1 > 0) { // compute LRT double max0, max1, max2; for (k = 0, max0 = -1; k <= ma->M; ++k) if (max0 < ma->z[k]) max0 = ma->z[k]; for (k = 0, max1 = -1; k <= ma->n1 * 2; ++k) if (max1 < ma->z1[k]) max1 = ma->z1[k]; for (k = 0, max2 = -1; k <= ma->M - ma->n1 * 2; ++k) if (max2 < ma->z2[k]) max2 = ma->z2[k]; rst->lrt = log(max1 * max2 / max0); rst->lrt = rst->lrt < 0? 1 : kf_gammaq(.5, rst->lrt); } else rst->lrt = -1.0; rst->cmp[0] = rst->cmp[1] = rst->cmp[2] = rst->p_chi2 = -1.0; if (do_contrast && rst->p_var > 0.5) // skip contrast2() if the locus is a strong non-variant rst->p_chi2 = contrast2(ma, rst->cmp); return 0; } void bcf_p1_dump_afs(bcf_p1aux_t *ma) { int k; fprintf(stderr, "[afs]"); for (k = 0; k <= ma->M; ++k) fprintf(stderr, " %d:%.3lf", k, ma->afs[ma->M - k]); fprintf(stderr, "\n"); memset(ma->afs, 0, sizeof(double) * (ma->M + 1)); } bcftools-1.21/prob1.h000066400000000000000000000067441467060157400144710ustar00rootroot00000000000000/* prob1.h -- mathematical utility functions. Copyright (C) 2010, 2011 Broad Institute. Copyright (C) 2012, 2013-2014 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef BCF_PROB1_H #define BCF_PROB1_H #include #include "call.h" typedef struct { int n; // Number of samples int M; // Total number of chromosomes across all samples (n*2 if all samples are diploid) int n1; int is_indel; uint8_t *ploidy; // haploid or diploid ONLY double *q2p, *pdg; // q2p maps from phread scaled to real likelihood, pdg -> P(D|g) double *phi; // Probability of seeing k reference alleles double *phi_indel; double *z, *zswap; // aux for afs double *z1, *z2, *phi1, *phi2; // only calculated when n1 is set double **hg; // hypergeometric distribution double *lf; // log factorial double t, t1, t2; double *afs, *afs1; // afs: accumulative allele frequency spectrum (AFS); afs1: site posterior distribution const int *PL; // point to PL int PL_len; int cons_llr; // pair and trio calling int64_t cons_gt; } bcf_p1aux_t; typedef struct { int rank0, perm_rank; // NB: perm_rank is always set to -1 by bcf_p1_cal() int ac; // ML alternative allele count double f_exp, f_flat, p_ref_folded, p_ref, p_var_folded, p_var; double cil, cih; double cmp[3], p_chi2, lrt; // used by contrast2() } bcf_p1rst_t; typedef struct { double p[4]; double edb, mqb, bqb; // end distance bias, mapQ bias, baseQ bias int mq, depth, is_tested, d[4]; } anno16_t; #define MC_PTYPE_FULL 1 #define MC_PTYPE_COND2 2 #define MC_PTYPE_FLAT 3 #ifdef __cplusplus extern "C" { #endif bcf_p1aux_t *bcf_p1_init(int n_smpl, uint8_t *ploidy); void bcf_p1_init_prior(bcf_p1aux_t *ma, int type, double theta); void bcf_p1_init_subprior(bcf_p1aux_t *ma, int type, double theta); void bcf_p1_destroy(bcf_p1aux_t *ma); void bcf_p1_set_ploidy(bcf1_t *b, bcf_p1aux_t *ma); int bcf_p1_cal(call_t *call, bcf1_t *b, int do_contrast, bcf_p1aux_t *ma, bcf_p1rst_t *rst); int bcf_p1_call_gt(const bcf_p1aux_t *ma, double f0, int k, int is_var); void bcf_p1_dump_afs(bcf_p1aux_t *ma); int bcf_p1_read_prior(bcf_p1aux_t *ma, const char *fn); int bcf_p1_set_n1(bcf_p1aux_t *b, int n1); void bcf_p1_set_folded(bcf_p1aux_t *p1a); // only effective when set_n1() is not called int bcf_em1(call_t *call, const bcf1_t *b, int n1, int flag, double x[10]); #ifdef __cplusplus } #endif #endif bcftools-1.21/rbuf.h000066400000000000000000000165701467060157400144020ustar00rootroot00000000000000/* rbuf.h -- round buffers. Copyright (C) 2013-2014, 2017 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __RBUF_H__ #define __RBUF_H__ #include typedef struct { int m,n,f; // m: allocated size, n: number of elements in the buffer, f: first element } rbuf_t; /** * rbuf_init() - initialize round buffer * @rbuf: the rbuf_t holder * @size: the maximum number of elements * */ static inline void rbuf_init(rbuf_t *rbuf, int size) { rbuf->m = size; rbuf->n = rbuf->f = 0; } /** * rbuf_kth() - get index of the k-th element of the round buffer * @rbuf: the rbuf_t holder * @k: 0-based index. If negative, return k-th element from the end, 1-based */ static inline int rbuf_kth(rbuf_t *rbuf, int k) { if ( k >= rbuf->n ) return -1; if ( k < 0 ) { k = rbuf->n + k; if ( k < 0 ) return -1; } int i = k + rbuf->f; if ( i >= rbuf->m ) i -= rbuf->m; return i; } /** * rbuf_last() - get index of the last element of the round buffer * @rbuf: the rbuf_t holder */ #define rbuf_last(rbuf) rbuf_kth(rbuf, -1) /** * rbuf_l2ridx() - get 0-based rbuf index which corresponds to i-th linear index * @rbuf: the rbuf_t holder * @idx: 0-based linear index * * Returns 0-based circular index or -1 if out of bounds */ static inline int rbuf_l2ridx(rbuf_t *rbuf, int idx) { if ( idx < 0 || idx >= rbuf->n ) return -1; if ( idx >= rbuf->f ) { int i = idx - rbuf->f; if ( i >= rbuf->n ) return -1; return i; } int i = rbuf->m - rbuf->f + idx; if ( i >= rbuf->n ) return -1; return i; } /** * rbuf_next() - get index of the next element in the round buffer * @rbuf: the rbuf_t holder * @i: pointer to the last rbuf index. Set to -1 before the first call. * * Sets i to the next position in the buffer. The return value indicates if * the position points to a valid element (1) or if there are no more elements * after *i (0). When the end is reached, *i is set to the first element in the * buffer. */ static inline int rbuf_next(rbuf_t *rbuf, int *i) { if ( !rbuf->n ) return 0; if ( *i==-1 ) { *i = rbuf->f; return 1; } int n = (rbuf->f <= *i) ? *i - rbuf->f + 1 : *i + rbuf->m - rbuf->f + 1; if ( ++(*i) >= rbuf->m ) *i = 0; if ( n < rbuf->n ) return 1; *i = rbuf->f; return 0; } /** * rbuf_prev() - get index of the previous element in the round buffer * @rbuf: the rbuf_t holder * @i: pointer to the last rbuf index. Set to -1 before the first call. * * Sets i to the previous position in the buffer. The return value indicates if * the position points to a valid element (1) or if there are no more elements * before *i (0). */ static inline int rbuf_prev(rbuf_t *rbuf, int *i) { if ( !rbuf->n || *i==rbuf->f ) return 0; if ( *i==-1 ) { *i = rbuf_last(rbuf); return 1; } if ( --(*i) < 0 ) *i = rbuf->m - 1; return 1; } /** * rbuf_prepend() - register new element at the start of the round buffer * @rbuf: the rbuf_t holder * * Returns index of the newly inserted element. */ static inline int rbuf_prepend(rbuf_t *rbuf) { if ( rbuf->n < rbuf->m ) rbuf->n++; rbuf->f = rbuf->f > 0 ? rbuf->f - 1 : rbuf->m - 1; return rbuf->f; } /** * rbuf_append() - register new element at the end of the round buffer * @rbuf: the rbuf_t holder * * Returns index of the newly inserted element. */ static inline int rbuf_append(rbuf_t *rbuf) { if ( rbuf->n < rbuf->m ) { rbuf->n++; int i = rbuf->f + rbuf->n; return i <= rbuf->m ? i - 1 : i - rbuf->m - 1; } rbuf->f++; if ( rbuf->f >= rbuf->m ) { rbuf->f = 0; return rbuf->m - 1; } return rbuf->f - 1; } /** * rbuf_shift() - removes first element from the buffer * @rbuf: the rbuf_t holder * * Returns index of the removed element. */ static inline int rbuf_shift(rbuf_t *rbuf) { if ( !rbuf->n ) return -1; int ret = rbuf->f; rbuf->f++; if ( rbuf->f >= rbuf->m ) rbuf->f = 0; rbuf->n--; return ret; } /** * rbuf_shift_n() - removes first n elements from the buffer * @rbuf: the rbuf_t holder * @n: number of elements to remove */ static inline void rbuf_shift_n(rbuf_t *rbuf, int n) { if ( n >= rbuf->n ) { rbuf->n = rbuf->f = 0; return; } rbuf->n -= n; rbuf->f += n; if ( rbuf->f >= rbuf->m ) rbuf->f -= rbuf->m; } /** * rbuf_expand0() - expand round buffer and set the newly allocated elements to 0 * @rbuf: the rbuf holder * @type_t: data type * @n: requested number of elements * @data: data array to be realloced * * Note: The new array is linearized and leaves the rbuf.f offset untouched, * thus the size of the new buffer is determined by the current position. */ #define rbuf_expand0(rbuf,type_t,n,data) \ { \ if ( n > (rbuf)->m ) \ { \ int m = n + (rbuf)->f; \ m--, m|=m>>1, m|=m>>2, m|=m>>4, m|=m>>8, m|=m>>16, m++; /* kroundup32 */ \ data = (type_t*) realloc(data, sizeof(type_t)*m); \ type_t *ptr = data; \ memset(ptr+(rbuf)->m,0,sizeof(type_t)*(m-(rbuf)->m)); \ if ( (rbuf)->f ) \ { \ memcpy(ptr+(rbuf)->m,ptr,sizeof(type_t)*(rbuf)->f); \ memset(ptr,0,sizeof(type_t)*(rbuf)->f); \ } \ (rbuf)->m = m; \ } \ } /** * rbuf_remove_kth() - remove k-th rbuf element (0-based) and memmove the data block * @rbuf: the rbuf holder * @type_t: data type * @k: k-th element to remove * @data: data array to be modified */ #define rbuf_remove_kth(rbuf, type_t, kth, data) \ { \ int k = rbuf_kth(rbuf, kth); \ if ( k < (rbuf)->f ) /* shrink from back */ \ { \ int l = rbuf_kth(rbuf, -1); \ if ( k < l ) \ { \ type_t tmp = (data)[k]; \ memmove(data+k, data+k+1, (l - k)*sizeof(type_t)); \ (data)[l] = tmp; \ } \ (rbuf)->n--; \ } \ else /* shrink from front */ \ { \ if ( k > (rbuf)->f ) \ { \ type_t tmp = (data)[k]; \ memmove(&data[(rbuf)->f+1], &data[(rbuf)->f], (k - (rbuf)->f)*sizeof(type_t)); \ (data)[(rbuf)->f] = tmp; \ } \ (rbuf)->f++; \ (rbuf)->n--; \ if ( (rbuf)->f == (rbuf)->m ) (rbuf)->f = 0; \ } \ } #endif bcftools-1.21/read_consensus.c000066400000000000000000000713271467060157400164530ustar00rootroot00000000000000/* read_consensus.c -- create and maintain consensus of reads Copyright (C) 2022 Genome Research Ltd. Author: pd3@sanger Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include "bcftools.h" #include "read_consensus.h" #include "cigar_state.h" #include "kheap.h" // Frequency arrays for each variant type #define NI 10 // number of alternative insertion sequences at one position in a single sample typedef struct { char *nt16_seq[NI]; int len[NI]; int freq[NI]; } ins_freq_t; typedef struct { int len[NI]; int freq[NI]; } del_freq_t; #define BF_DEL 5 typedef struct { int base[6]; // frequencies of A,C,G,T,N,deletion } base_freq_t; // Candidate variants for each interesting position to build consensus haplotypes enum variant_type { snv, ins, del, done }; typedef struct { enum variant_type vtype; hts_pos_t pos; // variant position (reference sequence coordinates), indels follow VCF convention int idx; // temporary 0-based index to rcns.cvar int which, // base/ins/del in rcns.[base|ins|del]_freq array depth; // coverage at the position float af, af_dev; // variant allele frequency (just for debugging printout) and absolute af deviation from 0.5 } candidate_var_t; static inline int cvar_not_preferred(candidate_var_t *a, candidate_var_t *b) { if ( a->af_dev == b->af_dev ) return a->depth < b->depth ? 1 : 0; return a->af_dev > b->af_dev ? 1 : 0; } KHEAP_INIT(cvh, candidate_var_t, cvar_not_preferred); typedef khp_cvh_t cvar_heap_t; #define MAX_NCVAR 8 // This results in alloc() of 2^MAX_NCVAR possible haplotypes #define NHAP (1<mfreq; i++) { ins_freq_t *ifrq = &rcns->ins_freq[i]; for (j=0; jnt16_seq[j]; j++) free(ifrq->nt16_seq[j]); } for (i=0; i<2; i++) free(rcns->cns[i].seq); free(rcns->ins_freq); free(rcns->del_freq); free(rcns->base_freq); free(rcns->stmp); khp_destroy(cvh,rcns->cv_heap); free(rcns); } static int init_arrays(read_cns_t *rcns) { int i,j,n = rcns->end - rcns->beg + 1; if ( n > rcns->mfreq ) { ins_freq_t *ifrq = (ins_freq_t*) realloc(rcns->ins_freq,sizeof(*rcns->ins_freq)*n); if ( !ifrq ) return -1; rcns->ins_freq = ifrq; memset(ifrq+rcns->mfreq,0,sizeof(*rcns->ins_freq)*(n-rcns->mfreq)); del_freq_t *dfrq = (del_freq_t*) realloc(rcns->del_freq,sizeof(*rcns->del_freq)*n); if ( !dfrq ) return -1; rcns->del_freq = dfrq; memset(dfrq+rcns->mfreq,0,sizeof(*rcns->del_freq)*(n-rcns->mfreq)); base_freq_t *bfrq = (base_freq_t*) realloc(rcns->base_freq,sizeof(*rcns->base_freq)*n); if ( !bfrq ) return -1; rcns->base_freq = bfrq; memset(bfrq+rcns->mfreq,0,sizeof(*rcns->base_freq)*(n-rcns->mfreq)); rcns->mfreq = n; } memset(rcns->base_freq,0,sizeof(*rcns->base_freq)*n); memset(rcns->del_freq,0,sizeof(*rcns->del_freq)*n); for (i=0; iins_freq[i]; for (j=0; jnt16_seq[j]; j++) free(ifrq->nt16_seq[j]); } memset(rcns->ins_freq,0,sizeof(*rcns->ins_freq)*n); return 0; } int rcns_reset(read_cns_t *rcns, hts_pos_t pos, hts_pos_t beg, hts_pos_t end) { rcns->band = 0; rcns->pos = pos; rcns->beg = beg; rcns->end = end; int i; for (i=0; i<2; i++) rcns->cns[i].nseq = rcns->cns[i].ipos = 0; // this should not be necessary if the caller did run all steps while (rcns->cv_heap->ndat) khp_delete(cvh, rcns->cv_heap); return init_arrays(rcns); } static inline void add_base(read_cns_t *rcns, int ref_pos, int nt16) { int i = ref_pos - rcns->beg; rcns->base_freq[i].base[seq_nt16_int[nt16]]++; } static void add_ins(read_cns_t *rcns, int ref_pos, int seq_pos, uint8_t *raw_seq, int len) { int i = ref_pos - rcns->beg; ins_freq_t *ifrq = &rcns->ins_freq[i]; char *str; if ( rcns->mstmp < len ) { str = realloc(rcns->stmp,len*sizeof(*str)); if ( !str ) return; rcns->mstmp = len; rcns->stmp = str; } else str = rcns->stmp; for (i=0; int16_seq[i]; i++) if ( ifrq->len[i]==len && !memcmp(ifrq->nt16_seq[i],str,len) ) break; if ( i>=NI ) return; // too many choices, typically homopolymers in long reads; discard if ( !ifrq->nt16_seq[i] ) // new insertion { if ( !(ifrq->nt16_seq[i]=malloc(len)) ) return; memcpy(ifrq->nt16_seq[i], str, len); ifrq->len[i] = len; } ifrq->freq[i]++; } static void add_del(read_cns_t *rcns, int ref_pos, int len) { int i = ref_pos - rcns->beg; int j,n = rcns->end - rcns->beg + 1; if ( i + len + 1 < n ) n = i + len + 1; for (j=i+1; jbase_freq[j].base[BF_DEL]++; del_freq_t *dfrq = &rcns->del_freq[i]; for (i=0; ilen[i]; i++) if ( dfrq->len[i]==len ) break; if ( i>=NI ) return; // too many choices, typically homopolymers in long reads; discard if ( !dfrq->len[i] ) dfrq->len[i] = len; // new deletion dfrq->freq[i]++; } read_cns_t *rcns_init(hts_pos_t pos, hts_pos_t beg, hts_pos_t end) { read_cns_t *rcns = (read_cns_t*) calloc(1,sizeof(read_cns_t)); rcns->pos = pos; rcns->beg = beg; rcns->end = end; rcns->cv_heap = khp_init(cvh); if ( init_arrays(rcns)!=0 ) { rcns_destroy(rcns); return NULL; } return rcns; } int rcns_set_reads(read_cns_t *rcns, bam_pileup1_t *plp, int nplp) { // save the reads for phasing, this can be called multiple times rcns->plp = plp; rcns->nplp = nplp; // fill consensus arrays int i,j,k, local_band_max = 0; // maximum absolute deviation from diagonal for (i=0; ib; int x = b->core.pos; // ref coordinate int y = 0; // seq coordinate uint32_t *cigar = bam_get_cigar(b); uint8_t *seq = bam_get_seq(b); int local_band = 0; // current deviation from diagonal for (k = 0; k < b->core.n_cigar; ++k) { int op = cigar[k] & BAM_CIGAR_MASK; int len = cigar[k] >> BAM_CIGAR_SHIFT; if ( op==BAM_CSOFT_CLIP ) y += len; else if ( op==BAM_CMATCH || op==BAM_CEQUAL || op==BAM_CDIFF ) { if ( xend && x+len>rcns->beg ) { int j_beg = rcns->beg > x ? rcns->beg - x : 0; // how many bases to skip in the ref and qry int j_end = rcns->end < x + len - 1 ? rcns->end - x : len - 1; x += j_beg; y += j_beg; for (j=j_beg; j<=j_end; j++, x++, y++) add_base(rcns,x,bam_seqi(seq,y)); } else { x += len; y += len; } } else if ( op==BAM_CINS ) { if ( x>rcns->beg && xend ) { local_band += p->indel; add_ins(rcns,x-1,y,seq,len); // x-1: one base before as in VCF } y += len; } else if ( op==BAM_CDEL || op==BAM_CREF_SKIP ) /* note: unsure about BAM_CREF_SKIP, don't have data to test */ { if ( x>rcns->beg && x+len-1<=rcns->end ) { local_band += -p->indel; add_del(rcns,x-1,len); // x-1: one base before as in VCF } x += len; } else if ( op==BAM_CHARD_CLIP ) continue; else error("rcns_set_reads todo: unknown cigar operator %d\n",op); if ( local_band_max < local_band ) local_band_max = local_band; } // Track the biggest deviation +/- from diagonal, used in BAQ alignment step. if ( rcns->band < local_band_max ) rcns->band = local_band_max; } return 0; } #if DEBUG_RCNS static void debug_print_base_freqs(read_cns_t *rcns, const char *ref) { int i,j,k,n = rcns->end - rcns->beg + 1; fprintf(stderr,"beg,end,pos=%d %d %d\n",(int)rcns->beg,(int)rcns->end,(int)rcns->pos); base_freq_t *bfreq = rcns->base_freq; ins_freq_t *ifreq = rcns->ins_freq; del_freq_t *dfreq = rcns->del_freq; for (i=0; ibeg+i+1,ref[i]); for (j=0; j<6; j++) fprintf(stderr,"\t%d%s",bfreq[i].base[j],ref[i]=="ACGTNi"[j]?"*":""); fprintf(stderr,"\t"); for (j=0; jncvar; i++) { candidate_var_t *var = &rcns->cvar[i]; fprintf(stderr,"\tvar%d pos=%"PRIhts_pos" idx=%d vtype=%s which=%d depth=%d af=%f af_dev=%f\n", i,var->pos+1,var->idx,vtype2string(var->vtype),var->which,var->depth,var->af,var->af_dev); } } static void debug_print_haplotype_frequency_spectrum(read_cns_t *rcns) { int i,j; fprintf(stderr,"Haplotype frequencies (bits from left correspond to var0,1,..):\n"); for (i=0; ihap_freq[i] ) continue; fprintf(stderr,"\t%d: ",i); for (j=0; jncvar; j++) fprintf(stderr,"%d", i&(1<hap_freq[i]); } } static void debug_print_consensus(read_cns_t *rcns, const char *ref) { int i,j,n = rcns->end - rcns->beg + 1; fprintf(stderr,"ref: "); for (i=0; icns[i].nseq ) break; fprintf(stderr,"Consensus%d: ",i); for (j=0; j<=rcns->cns[i].ipos; j++) fprintf(stderr,"%c","ACGTN"[(int)rcns->cns[i].seq[j]]); fprintf(stderr,"#"); for (; jcns[i].nseq; j++) fprintf(stderr,"%c","ACGTN"[(int)rcns->cns[i].seq[j]]); fprintf(stderr,"\n"); } } #else #define debug_print_base_freqs(rcns,ref) #define debug_print_candidate_variants(rcns) #define debug_print_haplotype_frequency_spectrum(rcns) #define debug_print_consensus(rcns,ref) #endif static int cvar_pos_cmp(const void *aptr, const void *bptr) { candidate_var_t *a = (candidate_var_t*)aptr; candidate_var_t *b = (candidate_var_t*)bptr; if ( a->pos < b->pos ) return -1; if ( a->pos > b->pos ) return 1; if ( a->vtype < b->vtype ) return -1; if ( a->vtype > b->vtype ) return 1; if ( a->which < b->which ) return -1; if ( a->which > b->which ) return 1; return 0; } static void register_variant(read_cns_t *rcns, enum variant_type vtype, int cns_pos, int which, int depth, float freq) { cvar_heap_t *cv_heap = rcns->cv_heap; if ( vtype==done ) { rcns->ncvar = 0; while (cv_heap->ndat) { rcns->cvar[rcns->ncvar++] = cv_heap->dat[0]; khp_delete(cvh,cv_heap); } // sort the variants by pos,type,which to make determination of haplotypes from reads faster if ( rcns->ncvar ) qsort(rcns->cvar, rcns->ncvar, sizeof(*rcns->cvar), cvar_pos_cmp); return; } candidate_var_t var; var.pos = cns_pos + rcns->beg; var.which = which; var.vtype = vtype; var.depth = depth; var.af_dev = fabs(0.5-freq); var.af = freq; int free_slot; // keep the number of variants small, maximum MAX_NCVAR if ( rcns->ncvar==MAX_NCVAR ) { if ( cvar_not_preferred(&var,&cv_heap->dat[0]) ) return; // no need to add, the new variant is worse than the heap's worst one free_slot = cv_heap->dat[0].idx; khp_delete(cvh,cv_heap); } else free_slot = rcns->ncvar++; var.idx = free_slot; rcns->cvar[free_slot] = var; khp_insert(cvh,cv_heap,&var); } // Identify candidate variant positions. (Note that homozygous variants are not considered // as those will be added trivially by taking the consensus base.) The detection limit is // for now hard-wired. This has only indirect effect on sensitivity, will just not contribute // to the consensus template when realigning. static int select_candidate_variants(read_cns_t *rcns, const char *ref) { const float af_th = 0.1; int i,j, n = rcns->end - rcns->beg + 1; int max_ins_len = 0; // maximum total length of all insertions applied to allocate big enough buffers base_freq_t *bfreq = rcns->base_freq; ins_freq_t *ifreq = rcns->ins_freq; del_freq_t *dfreq = rcns->del_freq; for (i=0; ipos - rcns->beg ) continue; // creating consensus from everything but the variants at the current position int dp = 0; for (j=0; j<4; j++) dp += bfreq[i].base[j]; for (j=0; jaf_th && af<(1-af_th) ) register_variant(rcns,snv,i,j,dp,af); } for (j=0; jaf_th && af<(1-af_th) ) register_variant(rcns,del,i,j,dp,af); } for (j=0; jaf_th && af<(1-af_th) ) register_variant(rcns,ins,i,j,dp,af); } } register_variant(rcns,done,0,0,0,0); // finalize // Reallocate buffers if ( rcns->mcns < n + max_ins_len ) { n += max_ins_len; for (i=0; i<2; i++) { char *seq = (char*) realloc(rcns->cns[i].seq,sizeof(char)*n); if ( !seq ) return -1; rcns->cns[i].seq = seq; } rcns->mcns = n; } // Find the longest deletion at the query position i = rcns->pos - rcns->beg; rcns->max_del = 0; for (j=0; jmax_del < dfreq[i].len[j] ) rcns->max_del = dfreq[i].len[j]; } return 0; } static int create_haplotype_frequency_spectrum(read_cns_t *rcns) { memset(rcns->hap_freq,0,sizeof(rcns->hap_freq)); int i; for (i=0; inplp; i++) // for each read... { const bam_pileup1_t *p = rcns->plp + i; cigar_state_t cigar; cstate_init(&cigar,p->b); int j,k,hap = 0; for (j=0; jncvar; j++) { candidate_var_t *cvar = &rcns->cvar[j]; if ( cvar->vtype==snv ) { int iseq = cstate_seek_op_fwd(&cigar, cvar->pos, BAM_CMATCH, NULL); if ( iseq==-2 ) break; if ( iseq==-1 ) continue; int nt16 = bam_seqi(cigar.seq, iseq); if ( seq_nt16_int[nt16]==cvar->which ) hap |= 1<vtype==ins ) { int len; ins_freq_t *ifrq = &rcns->ins_freq[cvar->pos - rcns->beg]; int iseq = cstate_seek_op_fwd(&cigar, cvar->pos+1, BAM_CINS, &len); if ( iseq==-2 ) break; if ( iseq==-1 ) continue; if ( len!=ifrq->len[cvar->which] ) continue; for (k=0; klen[cvar->which]; k++) if ( bam_seqi(cigar.seq,iseq+k)!=ifrq->nt16_seq[cvar->which][k] ) break; if ( k==ifrq->len[cvar->which] ) hap |= 1<vtype==del ) { int len; del_freq_t *dfrq = &rcns->del_freq[cvar->pos - rcns->beg]; int ret = cstate_seek_op_fwd(&cigar, cvar->pos+1, BAM_CDEL, &len); if ( ret==-2 ) break; if ( ret==-1 ) continue; if ( len!=dfrq->len[cvar->which] ) continue; hap |= 1<hap_freq[hap]++; } return 0; } typedef struct { int haplotype, count; } ii_t; static int ii_cmp(const void *a, const void *b) { if ( ((ii_t*)a)->count > ((ii_t*)b)->count ) return -1; if ( ((ii_t*)a)->count < ((ii_t*)b)->count ) return 1; return 0; } // Select two most common haplotypes trying to account for 1bp errors. Haplotypes // are represented as 8-bit numbers, each bit corresponds to one candidate variant. static int correct_haplotype_errors(read_cns_t *rcns) { int i,j, tot = 0; ii_t freq[NHAP]; for (i=0; ihap_freq[i]; tot += rcns->hap_freq[i]; } qsort(freq, NHAP, sizeof(ii_t), ii_cmp); // sort haplotypes in descending order for (i=NHAP-1; i>1; i--) { if ( !freq[i].count ) continue; if ( freq[1].count > tot - freq[0].count - freq[1].count ) break; // the top2 hapotypes cannot change anymore // Find a similar haplotype with the highest frequency. Assuming errors go in 0->1 // direction only and considering one error only. int count = freq[i].count, max_hap = 0; for (j=0; j=0 && haphap_freq[hap] ) count = rcns->hap_freq[hap], max_hap = hap; } if ( count == freq[i].count ) continue; // Update frequency and sort the two modified elements count = freq[i].count; freq[i].count = 0; rcns->hap_freq[freq[i].haplotype] = 0; rcns->hap_freq[max_hap] += count; for (j=i+1; j=0; j--) { if ( freq[j].haplotype==max_hap ) freq[j].count += count; // update the best matching haplotype if ( freq[j].count < freq[j+1].count ) { ii_t tmp = freq[j]; freq[j] = freq[j+1]; freq[j+1] = tmp; } } } // Use only one consensus if the next best haplotype is populated by less than 10% of reads rcns->ncns = ((float)freq[1].count / (freq[0].count + freq[1].count) < 0.1) ? 1 : 2; // Remove unused candidate variants from the top two haplotypes int hap0 = freq[0].haplotype; int hap1 = rcns->ncns==2 ? freq[1].haplotype : 0; rcns->cns_hap[0] = 0; rcns->cns_hap[1] = 0; for (i=0,j=0; icvar[j] = rcns->cvar[i]; if ( hap0 & (1U<cns_hap[0] |= 1U<cns_hap[1] |= 1U<ncvar = j; #if DEBUG_RCNS // This only matters for debugging print memset(rcns->hap_freq,0,NHAP*sizeof(*rcns->hap_freq)); rcns->hap_freq[rcns->cns_hap[1]] = freq[1].count; // NB: the order matters when ncns==1 rcns->hap_freq[rcns->cns_hap[0]] = freq[0].count; #endif return 0; } // Check how frequent are insertions adjacent to the j-th position. Note that reads with an // insertion usually increment also bfreq counts at this position, but not necessarily so, // therefore the counts are approximate static inline void apply_consensus_insertion(read_cns_t *rcns, cns_seq_t *cns, int j, int ivar) { // Only apply consensus insertions that are not being tested by bam2bcf_iaux, i.e. not at the current pos hts_pos_t ref_pos = rcns->beg + j; if ( rcns->pos == ref_pos ) return; // Only apply when there is no insertion at this position registered as a variant while ( ivar < rcns->ncvar && rcns->cvar[ivar].pos == ref_pos ) { if ( rcns->cvar[ivar].vtype == ins ) return; ivar++; } base_freq_t *bfreq = rcns->base_freq; ins_freq_t *ifreq = rcns->ins_freq; int k, nreads = 0; for (k=0; k max_freq*2 ) return; int len = ifreq[j].len[kmax]; char *seq = ifreq[j].nt16_seq[kmax]; for (k=0; kseq[cns->nseq++] = seq_nt16_int[(int)seq[k]]; } // For each position of the realignment window apply either the candidate variants // from ith haplotype or decide on the base/ins/del by majority vote static void create_consensus(read_cns_t *rcns, const char *ref, int ith) { int n = rcns->end - rcns->beg + 1; cns_seq_t *cns = &rcns->cns[ith]; base_freq_t *bfreq = rcns->base_freq; ins_freq_t *ifreq = rcns->ins_freq; del_freq_t *dfreq = rcns->del_freq; hts_pos_t prev_pos = 0; int j,k, ivar = 0; for (j=0; jbeg + j; if ( rcns->pos == ref_pos ) cns->ipos = cns->nseq; while ( ivar < rcns->ncvar && rcns->cvar[ivar].pos < ref_pos ) ivar++; if ( ivar >= rcns->ncvar || rcns->cvar[ivar].pos != ref_pos ) { // This position is not recognised as a het variant so take the most frequent base, including // a deletion if that is most frequent. However, for deleted bases make sure they are not part // of the deletion that is being tested at this positions int max_freq = 0, kmax = seq_nt16_int[seq_nt16_table[(int)ref[j]]]; int nk = ( ref_pos < rcns->pos || ref_pos > rcns->pos + rcns->max_del ) ? BF_DEL+1 : BF_DEL; for (k=0; kseq[cns->nseq++] = kmax; } // Only apply consensus insertions that are not being tested by bam2bcf_iaux, i.e. not at the current pos apply_consensus_insertion(rcns, cns, j, ivar); continue; } int which = rcns->cvar[ivar].which; if ( !(rcns->cns_hap[ith] & (1U<cvar[ivar].vtype==snv && rcns->cvar[ivar].which==k ) continue; if ( max_freq < bfreq[j].base[k] ) max_freq = bfreq[j].base[k], kmax = k; } if ( kmax!=BF_DEL && (!cns->nseq || prev_pos != ref_pos) ) { prev_pos = ref_pos; cns->seq[cns->nseq++] = kmax; } apply_consensus_insertion(rcns, cns, j, ivar); continue; } if ( rcns->cvar[ivar].vtype == snv ) { prev_pos = ref_pos; cns->seq[cns->nseq++] = which; apply_consensus_insertion(rcns, cns, j, ivar); continue; } // There can be multiple variants at this position, for example snv+ins. SNVs come first // thanks to cvar_pos_cmp(), make sure the base has not been added already. if ( !cns->nseq || prev_pos != ref_pos ) { int max_freq = 0, kmax = seq_nt16_int[seq_nt16_table[(int)ref[j]]]; for (k=0; k<6; k++) { if ( rcns->cvar[ivar].vtype==snv && rcns->cvar[ivar].which==k ) continue; if ( max_freq < bfreq[j].base[k] ) max_freq = bfreq[j].base[k], kmax = k; } if ( kmax!=BF_DEL ) { prev_pos = ref_pos; cns->seq[cns->nseq++] = kmax; } } if ( rcns->cvar[ivar].vtype == ins ) { int len = ifreq[j].len[which]; char *seq = ifreq[j].nt16_seq[which]; for (k=0; kseq[cns->nseq++] = seq_nt16_int[(int)seq[k]]; } } else if ( rcns->cvar[ivar].vtype == del ) j += dfreq[j].len[which]; } } // The algorithm: // 1. Identify heterozygous variant positions // 2. Sort variants by abs(variant_allele_freq-0.5) in descending order // 3. Take the top sorted variants (up to 8 to fit in uint8_t) and count the number of // corresponding reads to create frequency spectrum // 4. Correct errors, collapse to the requested number of haplotypes (consensus sequences) // using majority vote for the distribution tail cns_seq_t *rcns_get_consensus(read_cns_t *rcns, const char *ref) { debug_print_base_freqs(rcns, ref); select_candidate_variants(rcns, ref); debug_print_candidate_variants(rcns); if ( rcns->ncvar ) { create_haplotype_frequency_spectrum(rcns); debug_print_haplotype_frequency_spectrum(rcns); correct_haplotype_errors(rcns); debug_print_candidate_variants(rcns); debug_print_haplotype_frequency_spectrum(rcns); } else { rcns->cns_hap[0] = 0; rcns->ncns = 1; } // create consensus int i; for (i=0; incns; i++) create_consensus(rcns,ref,i); debug_print_consensus(rcns,ref); return rcns->cns; } bcftools-1.21/read_consensus.h000066400000000000000000000044651467060157400164570ustar00rootroot00000000000000/* read_consensus.h -- create and maintain consensus of reads Copyright (C) 2022 Genome Research Ltd. Author: pd3@sanger Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef READ_CONSENSUS_H #define READ_CONSENSUS_H #include #include #include #ifndef DEBUG_RCNS #define DEBUG_RCNS 0 #endif typedef struct { char *seq; // nt5 sequence: "ACGTN"[(int)seq[i]] int nseq, ipos; // the sequence length and the `pos` index relative to seq } cns_seq_t; typedef struct _read_cns_t read_cns_t; // Init and destroy read consensus read_cns_t *rcns_init(hts_pos_t pos, hts_pos_t beg, hts_pos_t end); void rcns_destroy(read_cns_t *rcns); // Reset the structures for new sample and/or position int rcns_reset(read_cns_t *rcns, hts_pos_t pos, hts_pos_t beg, hts_pos_t end); // Add reads to consensus. The provided structures must continue to exist // until rcns_get_consensus() is called. // // Todo (easy): allow it to be called once or multiple times, eg for // creating a shared consensus for multiple samples int rcns_set_reads(read_cns_t *rcns, bam_pileup1_t *plp, int nplp); // Generate up to two consensus sequences, cns_seq[1].nseq is 0 when only // the first is set cns_seq_t *rcns_get_consensus(read_cns_t *rcns, const char *ref); #endif bcftools-1.21/regidx.c000066400000000000000000000440461467060157400147200ustar00rootroot00000000000000/* Copyright (C) 2014-2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include "regidx.h" #define MAX_COOR_0 REGIDX_MAX // CSI and hts_itr_query limit, 0-based #define iBIN(x) ((x)>>13) typedef struct { uint32_t beg, end; } reg_t; typedef struct { uint32_t pos, ireg; // y-coordinate and a pointer to reglist.reg and reglist.dat } pos_t; typedef struct _reglist_t reglist_t; typedef struct { uint32_t beg, end, ireg; // query coordinates and the active region regidx_t *ridx; reglist_t *list; int active; } _itr_t; // List of regions for one chromosome. struct _reglist_t { uint32_t *idx, nidx; // index to list.reg+1 uint32_t nreg, mreg; // n:used, m:allocated reg_t *reg; // regions void *dat; // payload data char *seq; // sequence name int unsorted; }; // Container of all sequences struct _regidx_t { int nseq, mseq; // n:used, m:alloced reglist_t *seq; // regions for each sequence void *seq2regs; // hash for fast lookup from chr name to regions char **seq_names; regidx_free_f free; // function to free any data allocated by regidx_parse_f regidx_parse_f parse; // parse one input line void *usr; // user data to pass to regidx_parse_f int payload_size; void *payload; // temporary payload data set by regidx_parse_f (sequence is not known beforehand) kstring_t str; }; int regidx_seq_nregs(regidx_t *idx, const char *seq) { int iseq; if ( khash_str2int_get(idx->seq2regs, seq, &iseq)!=0 ) return 0; // no such sequence return idx->seq[iseq].nreg; } int regidx_nregs(regidx_t *idx) { int i, nreg = 0; for (i=0; inseq; i++) nreg += idx->seq[i].nreg; return nreg; } char **regidx_seq_names(regidx_t *idx, int *n) { *n = idx->nseq; return idx->seq_names; } int regidx_insert_list(regidx_t *idx, char *line, char delim) { kstring_t tmp = {0,0,0}; char *ss = line; while ( *ss ) { char *se = ss; while ( *se && *se!=delim ) se++; tmp.l = 0; kputsn(ss, se-ss, &tmp); if ( regidx_insert(idx,tmp.s) < 0 ) { free(tmp.s); return -1; } if ( !*se ) break; ss = se+1; } free(tmp.s); return 0; } static inline int cmp_regs(reg_t *a, reg_t *b) { if ( a->beg < b->beg ) return -1; if ( a->beg > b->beg ) return 1; if ( a->end < b->end ) return 1; // longer intervals come first if ( a->end > b->end ) return -1; return 0; } static int cmp_reg_ptrs(const void *a, const void *b) { return cmp_regs((reg_t*)a,(reg_t*)b); } static int cmp_reg_ptrs2(const void *a, const void *b) { return cmp_regs(*((reg_t**)a),*((reg_t**)b)); } inline int regidx_push(regidx_t *idx, char *chr_beg, char *chr_end, uint32_t beg, uint32_t end, void *payload) { if ( beg > MAX_COOR_0 ) beg = MAX_COOR_0; if ( end > MAX_COOR_0 ) end = MAX_COOR_0; int rid; idx->str.l = 0; kputsn(chr_beg, chr_end-chr_beg+1, &idx->str); if ( khash_str2int_get(idx->seq2regs, idx->str.s, &rid)!=0 ) { // new chromosome idx->nseq++; int m_prev = idx->mseq; hts_expand0(reglist_t,idx->nseq,idx->mseq,idx->seq); hts_expand0(char*,idx->nseq,m_prev,idx->seq_names); idx->seq_names[idx->nseq-1] = strdup(idx->str.s); rid = khash_str2int_inc(idx->seq2regs, idx->seq_names[idx->nseq-1]); } reglist_t *list = &idx->seq[rid]; list->seq = idx->seq_names[rid]; list->nreg++; int mreg = list->mreg; hts_expand(reg_t,list->nreg,list->mreg,list->reg); list->reg[list->nreg-1].beg = beg; list->reg[list->nreg-1].end = end; if ( idx->payload_size ) { if ( mreg != list->mreg ) list->dat = realloc(list->dat,idx->payload_size*list->mreg); memcpy((char *)list->dat + idx->payload_size*(list->nreg-1), payload, idx->payload_size); } if ( !list->unsorted && list->nreg>1 && cmp_regs(&list->reg[list->nreg-2],&list->reg[list->nreg-1])>0 ) list->unsorted = 1; return 0; } int regidx_insert(regidx_t *idx, char *line) { if ( !line ) return 0; char *chr_from, *chr_to; uint32_t beg,end; int ret = idx->parse(line,&chr_from,&chr_to,&beg,&end,idx->payload,idx->usr); if ( ret==-2 ) return -1; // error if ( ret==-1 ) return 0; // skip the line regidx_push(idx, chr_from,chr_to,beg,end,idx->payload); return 0; } regidx_t *regidx_init_string(const char *str, regidx_parse_f parser, regidx_free_f free_f, size_t payload_size, void *usr_dat) { regidx_t *idx = (regidx_t*) calloc(1,sizeof(regidx_t)); if ( !idx ) return NULL; idx->free = free_f; idx->parse = parser ? parser : regidx_parse_tab; idx->usr = usr_dat; idx->seq2regs = khash_str2int_init(); idx->payload_size = payload_size; if ( payload_size ) idx->payload = malloc(payload_size); kstring_t tmp = {0,0,0}; const char *ss = str; while ( *ss ) { while ( *ss && isspace(*ss) ) ss++; const char *se = ss; while ( *se && *se!='\r' && *se!='\n' ) se++; tmp.l = 0; kputsn(ss, se-ss, &tmp); regidx_insert(idx,tmp.s); while ( *se && isspace(*se) ) se++; ss = se; } free(tmp.s); return idx; } regidx_t *regidx_init(const char *fname, regidx_parse_f parser, regidx_free_f free_f, size_t payload_size, void *usr_dat) { if ( !parser ) { if ( !fname ) parser = regidx_parse_tab; else { int len = strlen(fname); if ( len>=7 && !strcasecmp(".bed.gz",fname+len-7) ) parser = regidx_parse_bed; else if ( len>=8 && !strcasecmp(".bed.bgz",fname+len-8) ) parser = regidx_parse_bed; else if ( len>=4 && !strcasecmp(".bed",fname+len-4) ) parser = regidx_parse_bed; else if ( len>=4 && !strcasecmp(".vcf",fname+len-4) ) parser = regidx_parse_vcf; else if ( len>=7 && !strcasecmp(".vcf.gz",fname+len-7) ) parser = regidx_parse_vcf; else parser = regidx_parse_tab; } } regidx_t *idx = (regidx_t*) calloc(1,sizeof(regidx_t)); idx->free = free_f; idx->parse = parser; idx->usr = usr_dat; idx->seq2regs = khash_str2int_init(); idx->payload_size = payload_size; if ( payload_size ) idx->payload = malloc(payload_size); if ( !fname ) return idx; kstring_t str = {0,0,0}; htsFile *fp = hts_open(fname,"r"); if ( !fp ) goto error; while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 ) { if ( regidx_insert(idx, str.s) ) goto error; } free(str.s); if ( hts_close(fp)!=0 ) { fprintf(stderr,"[%s] Error: close failed .. %s\n", __func__,fname); goto error; } return idx; error: free(str.s); if ( fp ) hts_close(fp); regidx_destroy(idx); return NULL; } void regidx_destroy(regidx_t *idx) { int i, j; for (i=0; inseq; i++) { reglist_t *list = &idx->seq[i]; if ( idx->free ) { for (j=0; jnreg; j++) idx->free((char *)list->dat + idx->payload_size*j); } free(list->dat); free(list->reg); free(list->idx); } free(idx->seq_names); free(idx->seq); free(idx->str.s); free(idx->payload); khash_str2int_destroy_free(idx->seq2regs); free(idx); } int _reglist_build_index(regidx_t *regidx, reglist_t *list) { int i; if ( list->unsorted ) { if ( !regidx->payload_size ) qsort(list->reg,list->nreg,sizeof(reg_t),cmp_reg_ptrs); else { reg_t **ptr = (reg_t**) malloc(sizeof(reg_t*)*list->nreg); for (i=0; inreg; i++) ptr[i] = list->reg + i; qsort(ptr,list->nreg,sizeof(*ptr),cmp_reg_ptrs2); void *tmp_dat = malloc(regidx->payload_size*list->nreg); for (i=0; inreg; i++) { size_t iori = ptr[i] - list->reg; memcpy((char *)tmp_dat+i*regidx->payload_size, (char *)list->dat+iori*regidx->payload_size, regidx->payload_size); } free(list->dat); list->dat = tmp_dat; reg_t *tmp_reg = (reg_t*) malloc(sizeof(reg_t)*list->nreg); for (i=0; inreg; i++) { size_t iori = ptr[i] - list->reg; tmp_reg[i] = list->reg[iori]; } free(ptr); free(list->reg); list->reg = tmp_reg; list->mreg = list->nreg; } list->unsorted = 0; } list->nidx = 0; int j,k, midx = 0; for (j=0; jnreg; j++) { int ibeg = iBIN(list->reg[j].beg); int iend = iBIN(list->reg[j].end); if ( midx <= iend ) { int old_midx = midx; midx = iend + 1; kroundup32(midx); list->idx = (uint32_t*) realloc(list->idx, midx*sizeof(uint32_t)); memset(list->idx+old_midx, 0, sizeof(uint32_t)*(midx-old_midx)); } if ( ibeg==iend ) { if ( !list->idx[ibeg] ) list->idx[ibeg] = j + 1; } else { for (k=ibeg; k<=iend; k++) if ( !list->idx[k] ) list->idx[k] = j + 1; } if ( list->nidx < iend+1 ) list->nidx = iend+1; } return 0; } int regidx_overlap(regidx_t *regidx, const char *chr, uint32_t beg, uint32_t end, regitr_t *regitr) { if ( regitr ) regitr->seq = NULL; int iseq, ireg; if ( khash_str2int_get(regidx->seq2regs, chr, &iseq)!=0 ) return 0; // no such sequence reglist_t *list = ®idx->seq[iseq]; if ( !list->nreg ) return 0; if ( list->nreg==1 ) { if ( beg > list->reg[0].end ) return 0; if ( end < list->reg[0].beg ) return 0; ireg = 0; } else { if ( !list->idx ) _reglist_build_index(regidx,list); int ibeg = iBIN(beg); if ( ibeg >= list->nidx ) return 0; // beg is too big // find a matching region uint32_t i = list->idx[ibeg]; if ( !i ) { int iend = iBIN(end); if ( iend > list->nidx ) iend = list->nidx; for (i=ibeg; i<=iend; i++) if ( list->idx[i] ) break; if ( i>iend ) return 0; i = list->idx[i]; } for (ireg=i-1; iregnreg; ireg++) { if ( list->reg[ireg].beg > end ) return 0; // no match, past the query region if ( list->reg[ireg].end >= beg && list->reg[ireg].beg <= end ) break; // found } if ( ireg >= list->nreg ) return 0; // no match } if ( !regitr ) return 1; // match, but no more info to save // may need to iterate over the matching regions later _itr_t *itr = (_itr_t*)regitr->itr; itr->ridx = regidx; itr->list = list; itr->beg = beg; itr->end = end; itr->ireg = ireg; itr->active = 0; regitr->seq = list->seq; regitr->beg = list->reg[ireg].beg; regitr->end = list->reg[ireg].end; if ( regidx->payload_size ) regitr->payload = (char *)list->dat + regidx->payload_size*ireg; return 1; } int regidx_parse_bed(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) return -1; // skip blank lines if ( *ss=='#' ) return -1; // skip comments char *se = ss; while ( *se && !isspace(*se) ) se++; *chr_beg = ss; *chr_end = se-1; if ( !*se ) { // just the chromosome name *beg = 0; *end = MAX_COOR_0; return 0; } ss = se+1; *beg = strtod(ss, &se); if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; } ss = se+1; *end = strtod(ss, &se) - 1; if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; } return 0; } int regidx_parse_tab(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) return -1; // skip blank lines if ( *ss=='#' ) return -1; // skip comments char *se = ss; while ( *se && !isspace(*se) ) se++; *chr_beg = ss; *chr_end = se-1; if ( !*se ) { // just the chromosome name *beg = 0; *end = MAX_COOR_0; return 0; } ss = se+1; *beg = strtod(ss, &se); if ( ss==se ) { fprintf(stderr,"Could not parse tab line: %s\n", line); return -2; } if ( *beg==0 ) { fprintf(stderr,"Could not parse tab line, expected 1-based coordinate: %s\n", line); return -2; } (*beg)--; if ( !se[0] || !se[1] ) *end = *beg; else { ss = se+1; *end = strtod(ss, &se); if ( ss==se || (*se && !isspace(*se)) ) *end = *beg; else if ( *end==0 ) { fprintf(stderr,"Could not parse tab line, expected 1-based coordinate: %s\n", line); return -2; } else (*end)--; } return 0; } int regidx_parse_vcf(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { int ret = regidx_parse_tab(line, chr_beg, chr_end, beg, end, payload, usr); if ( !ret ) *end = *beg; return ret; } int regidx_parse_reg(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) return -1; // skip blank lines if ( *ss=='#' ) return -1; // skip comments char *se = ss; while ( *se && *se!=':' ) se++; *chr_beg = ss; *chr_end = se-1; if ( !*se ) { *beg = 0; *end = MAX_COOR_0; return 0; } ss = se+1; *beg = strtod(ss, &se); if ( ss==se ) { fprintf(stderr,"Could not parse reg line: %s\n", line); return -2; } if ( *beg==0 ) { fprintf(stderr,"Could not parse reg line, expected 1-based coordinate: %s\n", line); return -2; } (*beg)--; if ( !se[0] || !se[1] ) *end = se[0]=='-' ? MAX_COOR_0 : *beg; else { ss = se+1; *end = strtod(ss, &se); if ( ss==se ) *end = *beg; else if ( *end==0 ) { fprintf(stderr,"Could not parse reg line, expected 1-based coordinate: %s\n", line); return -2; } else (*end)--; } return 0; } regitr_t *regitr_init(regidx_t *regidx) { regitr_t *regitr = (regitr_t*) calloc(1,sizeof(regitr_t)); regitr->itr = (_itr_t*) calloc(1,sizeof(_itr_t)); _itr_t *itr = (_itr_t*) regitr->itr; itr->ridx = regidx; itr->list = NULL; return regitr; } void regitr_reset(regidx_t *regidx, regitr_t *regitr) { _itr_t *itr = (_itr_t*) regitr->itr; memset(itr,0,sizeof(_itr_t)); itr->ridx = regidx; } void regitr_destroy(regitr_t *regitr) { free(regitr->itr); free(regitr); } int regitr_overlap(regitr_t *regitr) { if ( !regitr->seq ) return 0; _itr_t *itr = (_itr_t*) regitr->itr; if ( !itr->active ) { // is this the first call after regidx_overlap? itr->active = 1; itr->ireg++; return 1; } reglist_t *list = itr->list; int i; for (i=itr->ireg; inreg; i++) { if ( list->reg[i].beg > itr->end ) return 0; // no match, past the query region if ( list->reg[i].end >= itr->beg && list->reg[i].beg <= itr->end ) break; // found } if ( i >= list->nreg ) return 0; // no match itr->ireg = i + 1; regitr->seq = list->seq; regitr->beg = list->reg[i].beg; regitr->end = list->reg[i].end; if ( itr->ridx->payload_size ) regitr->payload = (char *)list->dat + itr->ridx->payload_size*i; return 1; } int regitr_loop(regitr_t *regitr) { _itr_t *itr = (_itr_t*) regitr->itr; regidx_t *regidx = itr->ridx; if ( !itr->list ) // first time here { itr->list = regidx->seq; itr->ireg = 0; } size_t iseq = itr->list - regidx->seq; if ( iseq >= regidx->nseq ) return 0; if ( itr->ireg >= itr->list->nreg ) { iseq++; if ( iseq >= regidx->nseq ) return 0; // no more sequences, done itr->ireg = 0; itr->list = ®idx->seq[iseq]; } regitr->seq = itr->list->seq; regitr->beg = itr->list->reg[itr->ireg].beg; regitr->end = itr->list->reg[itr->ireg].end; if ( regidx->payload_size ) regitr->payload = (char *)itr->list->dat + regidx->payload_size*itr->ireg; itr->ireg++; return 1; } void regitr_copy(regitr_t *dst, regitr_t *src) { _itr_t *dst_itr = (_itr_t*) dst->itr; _itr_t *src_itr = (_itr_t*) src->itr; *dst_itr = *src_itr; *dst = *src; dst->itr = dst_itr; } bcftools-1.21/regidx.h000066400000000000000000000170051467060157400147200ustar00rootroot00000000000000/* Copyright (C) 2014-2016, 2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Region indexing with an optional payload. Example of usage: // Init the parser and print regions. In this example the payload is a // pointer to a string. For the description of parse_custom and // free_custom functions, see regidx_parse_f and regidx_free_f below, // and for working example see test/test-regidx.c. regidx_t *idx = regidx_init(in_fname,parse_custom,free_custom,sizeof(char*),NULL); // Query overlap with chr:beg-end (beg,end are 1-based coordinates) regitr_t *itr = regitr_init(idx); if ( regidx_overlap(idx, chr,beg-1,end-1, itr) ) printf("There is an overlap!\n"); while ( regitr_overlap(itr) ) { printf("[%d,%d] overlaps with [%d,%d], payload=%s\n", beg,end, itr->beg+1, itr->end+1, regitr_payload(itr,char*)); } regidx_destroy(idx); regitr_destroy(itr); Another example, loop over all regions: regidx_t *idx = regidx_init(in_fname,NULL,NULL,0,NULL); regitr_t *itr = regitr_init(idx); while ( regitr_loop(itr) ) printf("chr=%s beg=%d end=%d\n", itr->seq, itr->beg+1, itr->end+1); regidx_destroy(idx); regitr_destroy(itr); */ #ifndef __REGIDX_H__ #define __REGIDX_H__ #include #include #ifdef __cplusplus extern "C" { #endif #define REGIDX_MAX 2147483646 // maximum regidx coordinate (0-based) typedef struct _regidx_t regidx_t; typedef struct { uint32_t beg,end; void *payload; char *seq; void *itr; } regitr_t; #define regitr_payload(itr,type_t) (*((type_t*)(itr)->payload)) /* * regidx_parse_f - Function to parse one input line, such as regidx_parse_bed * or regidx_parse_tab below. The function is expected to set `chr_from` and * `chr_to` to point to first and last character of chromosome name and set * coordinates `beg` and `end` (0-based, inclusive). If regidx_init() was * called with non-zero payload_size, the `payload` points to a memory * location of the payload_size and `usr` is the data passed to regidx_init(). * Any memory allocated by the function will be freed by regidx_free_f called * by regidx_destroy(). * * Return value: 0 on success, -1 to skip a record, -2 on fatal error. */ typedef int (*regidx_parse_f)(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr); typedef void (*regidx_free_f)(void *payload); /* * A note about the parsers: * - leading spaces are ignored * - lines starting with "#" are ignored */ int regidx_parse_bed(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); // CHROM or whitespace-sepatated CHROM,FROM,TO (0-based,right-open) int regidx_parse_tab(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); // CHROM or whitespace-separated CHROM,POS (1-based, inclusive) int regidx_parse_reg(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); // CHROM, CHROM:POS, CHROM:FROM-TO, CHROM:FROM- (1-based, inclusive) int regidx_parse_vcf(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); /* * regidx_init() - creates new index * regidx_init_string() - creates new index, from a string rather than from a file * * @param fname: input file name or NULL if regions will be added one-by-one via regidx_insert() * @param parsef: regidx_parse_bed, regidx_parse_tab or see description of regidx_parse_f. If NULL, * the format will be autodetected, currently either regidx_parse_tab (the default) or * regidx_parse_bed (file must be named 'bed' or 'bed.gz') will be used. Note that * the exact autodetection algorithm will change. * @param freef: NULL or see description of regidx_parse_f * @param payload_size: 0 with regidx_parse_bed, regidx_parse_tab or see regidx_parse_f * @param usr: optional user data passed to regidx_parse_f * * Returns index on success or NULL on error. */ regidx_t *regidx_init(const char *fname, regidx_parse_f parsef, regidx_free_f freef, size_t payload_size, void *usr); regidx_t *regidx_init_string(const char *string, regidx_parse_f parsef, regidx_free_f freef, size_t payload_size, void *usr); /* * regidx_destroy() - free memory allocated by regidx_init */ void regidx_destroy(regidx_t *idx); /* * regidx_overlap() - check overlap of the location chr:from-to with regions * @param beg,end: 0-based start, end coordinate (inclusive) * @param itr: pointer to iterator, can be NULL if regidx_loop not needed * * Returns 0 if there is no overlap or 1 if overlap is found. The overlapping * regions can be iterated as shown in the example above. */ int regidx_overlap(regidx_t *idx, const char *chr, uint32_t beg, uint32_t end, regitr_t *itr); /* * regidx_insert() - add a new region. * regidx_insert_list() - add new regions from a list * regidx_push() - low level insertion of a new region * * Returns 0 on success or -1 on error. */ int regidx_insert(regidx_t *idx, char *line); int regidx_insert_list(regidx_t *idx, char *line, char delim); int regidx_push(regidx_t *idx, char *chr_beg, char *chr_end, uint32_t beg, uint32_t end, void *payload); /* * regidx_seq_names() - return list of all sequence names */ char **regidx_seq_names(regidx_t *idx, int *n); /* * regidx_seq_nregs() - number of regions * regidx_nregs() - total number of regions */ int regidx_seq_nregs(regidx_t *idx, const char *seq); int regidx_nregs(regidx_t *idx); /* * regitr_init() - initialize an iterator. The idx parameter is required only * with regitr_loop. If only regitr_overlap is called, NULL * can be given. * * regitr_reset() - initialize an iterator for a repeated regitr_loop cycle. * Not required with regitr_overlap. */ regitr_t *regitr_init(regidx_t *idx); void regitr_destroy(regitr_t *itr); void regitr_reset(regidx_t *idx, regitr_t *itr); /* * regitr_overlap() - next overlapping region * Returns 0 when done or 1 when itr is set to next region */ int regitr_overlap(regitr_t *itr); /* * regitr_loop() - loop over all regions * Returns 0 when done or 1 when itr is set to next region */ int regitr_loop(regitr_t *itr); /* * regitr_copy() - create a copy of an iterator for a repeated iteration with regitr_loop */ void regitr_copy(regitr_t *dst, regitr_t *src); #ifdef __cplusplus } #endif #endif bcftools-1.21/reheader.c000066400000000000000000000634571467060157400152240ustar00rootroot00000000000000/* reheader.c -- reheader subcommand. Copyright (C) 2014-2022,2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #ifdef _WIN32 #include #endif #include #include #include // for hts_get_bgzfp() #include #include #include #include #include "bcftools.h" #include "khash_str2str.h" typedef struct _args_t { char **argv, *fname, *samples_fname, *header_fname, *output_fname; char *fai_fname; htsFile *fp; faidx_t *fai; htsFormat type; htsThreadPool *threads; int argc, n_threads; } args_t; static inline int is_escaped(const char *min, const char *str) { int n = 0; while ( --str>=min && *str=='\\' ) n++; return n%2; } static char *copy_and_update_contig_line(faidx_t *fai, char *line, void *chr_seen, kstring_t *dst) { kstring_t key = {0,0,0}, val = {0,0,0}, tmp = {0,0,0}; char *chr_name = NULL, *p, *q = line + 9; // skip ##contig= char *end = q; int nopen = 1; hts_pos_t chr_len = 0; while ( *end && *end!='\n' ) end++; while ( *q && *q!='\n' && nopen>0 ) { p = ++q; while ( *q && (*q==' ' || *q=='\t') ) { p++; q++; } // ^[A-Za-z_][0-9A-Za-z_.]*$ if (p==q && *q && (isalpha(*q) || *q=='_')) { q++; while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; } int n = q-p; int m = 0; while ( *q && (*q==' ' || *q=='\t') ) { q++; m++; } if ( *q!='=' || !n ) { char *x = q; while ( *x && *x!='\n' ) x++; *x = '\0'; error("Could not parse the line: %s [%s][%s]\n", line,p,q); } key.l = 0; kputsn(p,q-p-m,&key); p = ++q; while ( *q && (*q==' ' || *q=='\t') ) { p++; q++; } int quoted = *p=='"' ? 1 : 0; if ( quoted ) p++, q++; while ( *q && *q != '\n' ) { if ( quoted ) { if ( *q=='"' && !is_escaped(p,q) ) break; } else { if ( *q=='<' ) nopen++; if ( *q=='>' ) nopen--; if ( !nopen ) break; if ( *q==',' && nopen==1 ) break; } q++; } char *r = q; while ( r > p && r[-1] == ' ' ) r--; val.l = 0; kputsn(p,r-p,&val); if ( quoted && *q=='"' ) q++; if ( *q=='>' ) { nopen--; q++; } if ( !strcmp("length",key.s) ) continue; if ( !strcmp("ID",key.s) ) { if ( khash_str2int_has_key(chr_seen,val.s) ) continue; chr_len = faidx_seq_len64(fai, val.s); if ( chr_len==-1 ) { free(val.s); free(key.s); free(tmp.s); return end; // the sequence is not in fai, remove } chr_name = strdup(val.s); khash_str2int_inc(chr_seen, chr_name); continue; } kputc(',',&tmp); kputs(key.s,&tmp); kputc('=',&tmp); if ( quoted ) kputc('"',&tmp); kputs(val.s,&tmp); if ( quoted ) kputc('"',&tmp); } if ( !chr_name ) return end; ksprintf(dst,"##contig=",chr_name,chr_len,tmp.l ? tmp.s : ""); free(key.s); free(val.s); free(tmp.s); return q; } char *init_tmp_prefix(const char *tmp_prefix) { kstring_t prefix = {0,0,0}; if ( tmp_prefix ) { ksprintf(&prefix,"%sXXXXXX",tmp_prefix); return prefix.s; } char *tmpdir = getenv("TMPDIR"); if ( tmpdir ) kputs(tmpdir, &prefix); else { #ifdef _WIN32 char tmp_path[MAX_PATH]; int ret = GetTempPath(MAX_PATH, tmp_path); if (!ret || ret > MAX_PATH) error("Could not get the path to the temporary folder\n"); kputs(tmp_path, &prefix); #else kputs("/tmp", &prefix); #endif } kputs("/bcftools.XXXXXX", &prefix); return prefix.s; } static void update_from_fai(faidx_t *fai, kstring_t *hdr_txt) { kstring_t hdr_txt_new = {0,0,0}; // update the existing contig lines and remove lines not present in the fai file void *chr_seen = khash_str2int_init(); char *tmp, *beg = hdr_txt->s; while ( beg && *beg ) { tmp = strstr(beg, "\n##contig=<"); if ( !tmp ) break; kputsn(beg, tmp-beg+1, &hdr_txt_new); size_t l_prev = hdr_txt_new.l; beg = copy_and_update_contig_line(fai,tmp+1,chr_seen, &hdr_txt_new); if ( l_prev==hdr_txt_new.l ) hdr_txt_new.l--; // nothing was added, remove the newline } if ( !beg || !(tmp=strstr(beg,"\n#CHROM")) ) error("Failed to parse the header, #CHROM not found\n"); kputsn(beg, tmp-beg+1, &hdr_txt_new); // add any new contig lines int i, n = faidx_nseq(fai); for (i=0; i\n",faidx_iseq(fai,i),faidx_seq_len64(fai,faidx_iseq(fai,i))); } kputs(tmp+1,&hdr_txt_new); // Switch the new header content for the old free(hdr_txt->s); memcpy(hdr_txt, &hdr_txt_new, sizeof(*hdr_txt)); khash_str2int_destroy_free(chr_seen); } static void read_header_file(char *fname, kstring_t *hdr) { kstring_t tmp = {0,0,0}; hdr->l = 0; htsFile *fp = hts_open(fname, "r"); if ( !fp ) error("Could not read: %s\n", fname); while ( hts_getline(fp, KS_SEP_LINE, &tmp) > 0 ) { kputsn(tmp.s,tmp.l,hdr); kputc('\n',hdr); } if ( hts_close(fp) ) error("Close failed: %s\n", fname); free(tmp.s); while ( hdr->l>0 && isspace(hdr->s[hdr->l-1]) ) hdr->l--; // remove trailing newlines kputc('\n',hdr); } static int set_sample_pairs(char **samples, int nsamples, kstring_t *hdr, int idx) { int i, j, n; kstring_t key = {0,0,0}; kstring_t val = {0,0,0}; // Are these samples "old-name new-name" pairs? void *hash = khash_str2str_init(); for (i=0; il>0 && isspace(hdr->s[hdr->l-1]) ) hdr->l--; // remove trailing newlines hdr->s[hdr->l] = 0; kstring_t tmp = {0,0,0}; i = j = n = 0; // i:traverse the #CHROM line 1 by 1; j:points to the last column while ( hdr->s[idx+i] ) { if ( hdr->s[idx+i]=='\t' ) { hdr->s[idx+i] = 0; if ( ++n>9 ) { char *new_name = khash_str2str_get(hash,hdr->s+idx+j); kputs(new_name ? new_name : hdr->s+idx+j, &tmp); } else kputs(hdr->s+idx+j, &tmp); kputc('\t',&tmp); j = ++i; continue; } i++; } char *new_name = khash_str2str_get(hash,hdr->s+idx+j); kputs(new_name ? new_name : hdr->s+idx+j, &tmp); khash_str2str_destroy_free_all(hash); hdr->l = idx; kputs(tmp.s, hdr); kputc('\n', hdr); free(tmp.s); return 1; } static void set_samples(char **samples, int nsamples, kstring_t *hdr) { // Find the beginning of the #CHROM line int i = hdr->l - 2, ncols = 0; while ( i>=0 && hdr->s[i]!='\n' ) { if ( hdr->s[i]=='\t' ) ncols++; i--; } if ( i<0 || strncmp(hdr->s+i+1,"#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO\tFORMAT",45) ) { if ( i>0 && !strncmp(hdr->s+i+1,"#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO",38) ) error("Error: missing FORMAT fields, cowardly refusing to add samples\n"); error("Could not parse the header: %s\n", hdr->s); } // Are the samples "old-sample new-sample" pairs? if ( set_sample_pairs(samples,nsamples,hdr, i+1) ) return; // Replace all samples if ( ncols!=nsamples+8 ) fprintf(stderr, "Warning: different number of samples: %d vs %d\n", nsamples,ncols-8); ncols = 0; while ( ncols!=9 ) { i++; if ( hdr->s[i]=='\t' ) ncols++; } hdr->l = i; for (i=0; ifp); if ( !fp || bgzf_read_block(fp) != 0 || !fp->block_length ) error("Failed to read %s: %s\n", args->fname, strerror(errno)); kstring_t hdr = {0,0,0}; char *buffer = (char*) fp->uncompressed_block; // Read the header and find the position of the data block if ( buffer[0]!='#' ) error("Could not parse the header, expected '#', found '%c'\n", buffer[0]); int skip_until = 1; // end of the header in the current uncompressed block while (1) { if ( buffer[skip_until]=='\n' ) { skip_until++; if ( skip_until>=fp->block_length ) { kputsn(buffer,skip_until,&hdr); if ( bgzf_read_block(fp) != 0 ) error("Error reading %s\n", args->fname); if ( !fp->block_length ) break; skip_until = 0; } // The header has finished if ( buffer[skip_until]!='#' ) { kputsn(buffer,skip_until,&hdr); break; } } skip_until++; if ( skip_until>=fp->block_length ) { kputsn(buffer,fp->block_length,&hdr); if ( bgzf_read_block(fp) != 0 ) error("Error reading %s\n", args->fname); if ( !fp->block_length ) break; skip_until = 0; } } int nsamples = 0; char **samples = NULL; if ( args->samples_fname ) { samples = hts_readlines(args->samples_fname, &nsamples); if ( !samples || !nsamples ) error("Error reading the --samples file \"%s\"\n", args->samples_fname); } if ( args->header_fname ) { free(hdr.s); hdr.s = NULL; hdr.l = hdr.m = 0; read_header_file(args->header_fname, &hdr); } if ( args->fai ) update_from_fai(args->fai, &hdr); if ( samples ) { set_samples(samples, nsamples, &hdr); int i; for (i=0; ioutput_fname ? args->output_fname : "-","w");; if ( bgzf_write(bgzf_out, hdr.s, hdr.l) < 0 ) error("Can't write BGZF header (code %d)\n", bgzf_out->errcode); free(hdr.s); // Output all remaining data read with the header block if ( fp->block_length - skip_until > 0 ) { if ( bgzf_write(bgzf_out, buffer+skip_until, fp->block_length-skip_until)<0 ) error("Error: %d\n",fp->errcode); } if ( bgzf_flush(bgzf_out)<0 ) error("Error: %d\n",bgzf_out->errcode); // Stream the rest of the file without as it is, without decompressing ssize_t nread; const size_t page_size = 32768; char *buf = (char*) malloc(page_size); while (1) { nread = bgzf_raw_read(fp, buf, page_size); if ( nread<=0 ) break; int count = bgzf_raw_write(bgzf_out, buf, nread); if (count != nread) error("Write failed, wrote %d instead of %d bytes.\n", count,(int)nread); } if (bgzf_close(bgzf_out) < 0) error("Error closing %s: %d\n",args->output_fname ? args->output_fname : "-",bgzf_out->errcode); if (hts_close(args->fp)) error("Error closing %s: %d\n",args->fname,fp->errcode); free(buf); } static void reheader_vcf(args_t *args) { kstring_t hdr = {0,0,0}; htsFile *fp = args->fp; while ( hts_getline(fp, KS_SEP_LINE, &fp->line) >=0 ) { kputc('\n',&fp->line); // hts_getline eats the newline character if ( fp->line.s[0]!='#' ) break; kputsn(fp->line.s,fp->line.l,&hdr); } int nsamples = 0; char **samples = NULL; if ( args->samples_fname ) { samples = hts_readlines(args->samples_fname, &nsamples); if ( !samples || !nsamples ) error("Error reading the --samples file \"%s\"\n", args->samples_fname); } if ( args->header_fname ) { free(hdr.s); hdr.s = NULL; hdr.l = hdr.m = 0; read_header_file(args->header_fname, &hdr); } if ( args->fai ) update_from_fai(args->fai, &hdr); if ( samples ) { set_samples(samples, nsamples, &hdr); int i; for (i=0; ioutput_fname ? open(args->output_fname, O_WRONLY|O_CREAT|O_TRUNC, 0666) : STDOUT_FILENO; if ( out==-1 ) error("%s: %s\n", args->output_fname,strerror(errno)); if ( write(out, hdr.s, hdr.l)!=hdr.l ) error("Failed to write %"PRIu64" bytes\n", (uint64_t)hdr.l); free(hdr.s); if ( fp->line.l ) { if ( write(out, fp->line.s, fp->line.l)!=fp->line.l ) error("Failed to write %"PRIu64" bytes\n", (uint64_t)fp->line.l); } while ( hts_getline(fp, KS_SEP_LINE, &fp->line) >=0 ) // uncompressed file implies small size, we don't worry about speed { kputc('\n',&fp->line); if ( write(out, fp->line.s, fp->line.l)!=fp->line.l ) error("Failed to write %"PRIu64" bytes\n", (uint64_t)fp->line.l); } if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fname); if ( close(out)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); } static bcf_hdr_t *strip_header(bcf_hdr_t *src, bcf_hdr_t *dst) { bcf_hrec_t *src_hrec, *dst_hrec, *tmp; bcf_hdr_t *out = bcf_hdr_init("r"); int i; for (i=0; inhrec; i++) { // first insert lines which do not code BCF ids, their order does not matter dst_hrec = dst->hrec[i]; if ( dst_hrec->type==BCF_HL_FLT || dst_hrec->type==BCF_HL_INFO || dst_hrec->type==BCF_HL_FMT || dst_hrec->type== BCF_HL_CTG ) continue; bcf_hdr_add_hrec(out, bcf_hrec_dup(dst_hrec)); } for (i=0; inhrec; i++) { // now transfer header lines which define BCF ids src_hrec = src->hrec[i]; if ( src_hrec->type==BCF_HL_FLT || src_hrec->type==BCF_HL_INFO || src_hrec->type==BCF_HL_FMT || src_hrec->type== BCF_HL_CTG ) { int j = bcf_hrec_find_key(src_hrec, "ID"); dst_hrec = bcf_hdr_get_hrec(dst, src_hrec->type, "ID", src_hrec->vals[j], NULL); if ( !dst_hrec ) continue; tmp = bcf_hrec_dup(dst_hrec); j = bcf_hrec_find_key(src_hrec, "IDX"); if ( j>=0 ) { j = atoi(src_hrec->vals[j]); if (hrec_add_idx(tmp, j) < 0) error_errno("[%s] Failed to add IDX header", __func__); } bcf_hdr_add_hrec(out, tmp); } } if (bcf_hdr_sync(out) < 0) error_errno("[%s] Failed to update header", __func__); for (i=0; inhrec; i++) { // finally add new structured fields dst_hrec = dst->hrec[i]; if ( dst_hrec->type==BCF_HL_FLT || dst_hrec->type==BCF_HL_INFO || dst_hrec->type==BCF_HL_FMT || dst_hrec->type== BCF_HL_CTG ) { int j = bcf_hrec_find_key(dst_hrec, "ID"); tmp = bcf_hdr_get_hrec(out, dst_hrec->type, "ID", dst_hrec->vals[j], NULL); if ( !tmp ) bcf_hdr_add_hrec(out, bcf_hrec_dup(dst_hrec)); } } for (i=0; in[BCF_DT_SAMPLE]; i++) bcf_hdr_add_sample(out, dst->samples[i]); bcf_hdr_destroy(dst); return out; } static void reheader_bcf(args_t *args, int is_compressed) { htsFile *fp = args->fp; if ( args->n_threads > 0 ) { args->threads = (htsThreadPool *) calloc(1, sizeof(htsThreadPool)); if ( !args->threads ) error("Could not allocate memory\n"); if ( !(args->threads->pool = hts_tpool_init(args->n_threads)) ) error("Could not initialize threading\n"); hts_set_thread_pool(fp, args->threads); } bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("Failed to read the header: %s\n", args->fname); kstring_t htxt = {0,0,0}; bcf_hdr_format(hdr, 1, &htxt); int i, nsamples = 0; char **samples = NULL; if ( args->samples_fname ) { samples = hts_readlines(args->samples_fname, &nsamples); if ( !samples || !nsamples ) error("Error reading the --samples file \"%s\"\n", args->samples_fname); } if ( args->header_fname ) { free(htxt.s); htxt.s = NULL; htxt.l = htxt.m = 0; read_header_file(args->header_fname, &htxt); } if ( args->fai ) update_from_fai(args->fai, &htxt); if ( samples ) { set_samples(samples, nsamples, &htxt); for (i=0; iheader_fname ) hdr_out = strip_header(hdr, hdr_out); // write the header and the body htsFile *fp_out = hts_open(args->output_fname ? args->output_fname : "-",is_compressed ? "wb" : "wbu"); if ( !fp_out ) error("%s: %s\n", args->output_fname ? args->output_fname : "-", strerror(errno)); if ( args->threads ) hts_set_thread_pool(fp_out, args->threads); if ( bcf_hdr_write(fp_out, hdr_out)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->output_fname ? args->output_fname : "standard output"); bcf1_t *rec = bcf_init(); while ( bcf_read(fp, hdr, rec)==0 ) { // sanity checking, this slows things down. Make it optional? bcf_unpack(rec, BCF_UN_ALL); if ( rec->rid >= hdr_out->n[BCF_DT_CTG] || strcmp(bcf_hdr_int2id(hdr,BCF_DT_CTG,rec->rid),bcf_hdr_int2id(hdr_out,BCF_DT_CTG,rec->rid)) ) error("The CHROM is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_CTG,rec->rid)); for (i=0; id.n_flt; i++) { int id = rec->d.flt[i]; if ( id >= hdr_out->n[BCF_DT_ID] ) break; if ( !bcf_hdr_idinfo_exists(hdr_out,BCF_HL_FLT,id) ) break; if ( strcmp(hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key) ) error("FIXME: Broken FILTER ids: %s vs %s\n", hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key); } if ( i!=rec->d.n_flt ) error("The FILTER is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.flt[i])); for (i=0; in_info; i++) { int id = rec->d.info[i].key; if ( id >= hdr_out->n[BCF_DT_ID] ) break; if ( !hdr_out->id[BCF_DT_ID][id].key ) break; if ( !bcf_hdr_idinfo_exists(hdr_out,BCF_HL_INFO,id) ) break; if ( strcmp(hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key) ) error("FIXME: Broken INFO ids: %s vs %s\n", hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key); } if ( i!=rec->n_info ) error("The INFO tag is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.info[i].key)); for (i=0; in_fmt; i++) { int id = rec->d.fmt[i].id; if ( id >= hdr_out->n[BCF_DT_ID] ) break; if ( !hdr_out->id[BCF_DT_ID][id].key ) break; if ( !bcf_hdr_idinfo_exists(hdr_out,BCF_HL_FMT,id) ) break; if ( strcmp(hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key) ) error("FIXME: Broken FORMAT ids: %s vs %s\n", hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key); } if ( i!=rec->n_fmt ) error("The FORMAT tag is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.fmt[i].id)); if ( bcf_write(fp_out,hdr_out,rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname ? args->output_fname : "standard output"); } bcf_destroy(rec); free(htxt.s); if ( hts_close(fp_out)!=0 ) error("[%s] Error: failed to close the file %s\n",__func__,args->output_fname ? args->output_fname : "standard output"); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fname); bcf_hdr_destroy(hdr_out); bcf_hdr_destroy(hdr); if ( args->threads ) { hts_tpool_destroy(args->threads->pool); free(args->threads); } } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Modify header of VCF/BCF files, change sample names.\n"); fprintf(stderr, "Usage: bcftools reheader [OPTIONS] \n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -f, --fai FILE update sequences and their lengths from the .fai file\n"); fprintf(stderr, " -h, --header FILE new header\n"); fprintf(stderr, " -o, --output FILE write output to a file [standard output]\n"); fprintf(stderr, " -s, --samples FILE new sample names\n"); fprintf(stderr, " -T, --temp-prefix PATH ignored; was template for temporary file name\n"); fprintf(stderr, " --threads INT use multithreading with worker threads (BCF only) [0]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Example:\n"); fprintf(stderr, " # Write out the header to be modified\n"); fprintf(stderr, " bcftools view -h old.bcf > header.txt\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Edit the header using your favorite text editor\n"); fprintf(stderr, " vi header.txt\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Reheader the file\n"); fprintf(stderr, " bcftools reheader -h header.txt -o new.bcf old.bcf\n"); fprintf(stderr, "\n"); exit(1); } int main_reheader(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; static struct option loptions[] = { {"temp-prefix",1,0,'T'}, {"fai",1,0,'f'}, {"output",1,0,'o'}, {"header",1,0,'h'}, {"samples",1,0,'s'}, {"threads",1,NULL,1}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "s:h:o:f:T:",loptions,NULL)) >= 0) { switch (c) { case 1 : args->n_threads = strtol(optarg, 0, 0); break; case 'T': break; // unused - was temp file prefix case 'f': args->fai_fname = optarg; break; case 'o': args->output_fname = optarg; break; case 's': args->samples_fname = optarg; break; case 'h': args->header_fname = optarg; break; case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else usage(args); } else args->fname = argv[optind]; if ( args->fai_fname ) { args->fai = fai_load3(args->fai_fname,args->fai_fname,NULL,FAI_FASTA); if ( !args->fai ) error("Could not parse %s\n", args->fai_fname); } if ( !args->samples_fname && !args->header_fname && !args->fai) usage(args); if ( !args->fname ) usage(args); args->fp = hts_open(args->fname,"r"); if ( !args->fp ) error("Failed to read from %s\n", !strcmp("-",args->fname)?"standard input":args->fname); args->type = *hts_get_format(args->fp); if ( args->type.format==vcf ) { if ( args->type.compression==bgzf ) reheader_vcf_gz(args); else if ( args->type.compression==no_compression ) reheader_vcf(args); else if ( args->type.compression==gzip ) error("Error: cannot reheader gzip-compressed files, first convert with `bcftools view --output-type` to a supported format\n"); else error("Error: the compression type of \"%s\" is not recognised/supported\n", args->fname); } else reheader_bcf(args, args->type.compression==bgzf || args->type.compression==gzip); if (args->fai) fai_destroy(args->fai); free(args); return 0; } bcftools-1.21/smpl_ilist.c000066400000000000000000000121711467060157400156070ustar00rootroot00000000000000/* Copyright (C) 2016-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include "bcftools.h" #include "smpl_ilist.h" void smpl_ilist_destroy(smpl_ilist_t *smpl) { int i; if ( smpl->pair ) { for (i=0; in; i++) free(smpl->pair[i]); free(smpl->pair); } free(smpl->idx); free(smpl); } static inline int is_space_or_escaped(const char *min, const char *str) { if ( !isspace(*str) ) return 0; int n = 0; while ( --str>=min && *str=='\\' ) n++; return n%2 ? 0 : 1; } smpl_ilist_t *smpl_ilist_init(bcf_hdr_t *hdr, char *sample_list, int is_file, int flags) { smpl_ilist_t *smpl = (smpl_ilist_t*) calloc(1,sizeof(smpl_ilist_t)); int i; if ( !sample_list ) { smpl->n = bcf_hdr_nsamples(hdr); smpl->idx = (int*) malloc(sizeof(int)*smpl->n); for (i=0; in; i++) smpl->idx[i] = i; return smpl; } int negate = sample_list[0]=='^' ? 1 : 0; int nlist; char **list = hts_readlist(negate?sample_list+1:sample_list, is_file, &nlist); if ( !list ) error("Could not parse %s\n", sample_list); if ( negate && (flags&SMPL_REORDER) ) flags &= ~SMPL_REORDER; // preserve the VCF order unless flags&SMPL_REORDER is set int j = 0; int *tmp = (int*)calloc(bcf_hdr_nsamples(hdr),sizeof(int)); char **pair = NULL; for (i=0; in++; } if ( flags & SMPL_REORDER ) { smpl->idx = tmp; for (i=0; in = bcf_hdr_nsamples(hdr) - smpl->n; smpl->idx = (int*) malloc(sizeof(int)*smpl->n); j = 0; if ( !negate ) { if ( pair ) smpl->pair = (char**) calloc(smpl->n,sizeof(char*)); for (i=0; iidx[j] = i; if ( pair && pair[i] ) smpl->pair[j] = pair[i]; j++; } } else { for (i=0; iidx[j++] = i; } free(tmp); free(pair); for (i=0; in = bcf_hdr_nsamples(hdr_a); smpl->idx = (int*) malloc(sizeof(int)*smpl->n); for (i=0; in; i++) { const char *name = bcf_hdr_int2id(hdr_a, BCF_DT_SAMPLE, i); smpl->idx[i] = bcf_hdr_id2int(hdr_b, BCF_DT_SAMPLE, name); if ( flags&SMPL_STRICT && smpl->idx[i]<0 ) error("The sample %s is not present in the second file\n", name); } return smpl; } bcftools-1.21/smpl_ilist.h000066400000000000000000000043111467060157400156110ustar00rootroot00000000000000/* Copyright (C) 2016-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Parse --samples and --samples-file */ #ifndef __SMPL_ILIST_H__ #define __SMPL_ILIST_H__ #include #define SMPL_NONE 0 // flexible error recovery #define SMPL_STRICT 1 // samples must exist #define SMPL_SINGLE 2 // single sample expected #define SMPL_PAIR1 4 // two samples expected, the first is from the bcf hdr #define SMPL_PAIR2 8 // two samples expected, the second is from the bcf hdr #define SMPL_VERBOSE 16 // print warnings #define SMPL_REORDER 32 // reorder samples as asked, sample_list[i] points to the VCF header index typedef struct { char **pair; // the other sample in the pair int *idx; // index to bcf_hdr_t.samples; the first (SMPL_SINGLE|SMPL_PAIR1) or second sample (SMPL_PAIR2) int n; } smpl_ilist_t; // Pass NULL for sample_list to get all samples smpl_ilist_t *smpl_ilist_init(bcf_hdr_t *hdr, char *sample_list, int is_file, int flags); smpl_ilist_t *smpl_ilist_map(bcf_hdr_t *hdr_a, bcf_hdr_t *hdr_b, int flags); void smpl_ilist_destroy(smpl_ilist_t *smpl); #endif bcftools-1.21/str_finder.c000066400000000000000000000247251467060157400155770ustar00rootroot00000000000000/* str_finder.c -- Short Tandem Repeat finder. Originally from Crumble (https://github.com/jkbonfield/crumble) Copyright (C) 2015-2016, 2021-2022 Genome Research Ltd. Author: James Bonfield Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include "str_finder.h" #include "utlist.h" #define MAX(a,b) ((a)>(b)?(a):(b)) #define MIN(a,b) ((a)<(b)?(a):(b)) typedef unsigned char uc; static void add_rep(rep_ele **list, char *cons, int clen, int pos, int rlen, int lower_only, unsigned int w) { rep_ele *el, *tmp, *prev; char *cp1, *cp2, *cp_end; int i; // Already handled this in previous overlap? if (*list) { tmp = DL_TAIL(*list); if (tmp->start <= pos-rlen*2+1 && tmp->end >= pos) return; } // Find current and last occurrence of repeated word. cp2 = &cons[pos+1]; // If unpadded, this is quicker: cp1 = &cons[pos+1-rlen]; for (cp1 = &cons[pos], i = 1; i < rlen; cp1--) // compensate for pads if (*cp1 == '*') continue; else i++; while (*cp1 == '*') cp1--; // Scan ahead to see how much further it goes. cp_end = &cons[clen]; while (cp2 < cp_end) { if (*cp1 != *cp2) break; w<<=2; w|=*cp2; cp1++; cp2++; } if (!(el = malloc(sizeof(*el)))) return; el->end = pos + cp2-&cons[pos+1]; el->rep_len = rlen; pos++; while (rlen--) { while (cons[--pos] == '*'); while (cons[--pos] == '*'); } //pos++; while (pos > 1 && cons[pos-1] == '*') pos--; el->start = pos; // Check it meets the lower-case only criteria if (lower_only) { int lc = 0; for (i = el->start; i <= el->end; i++) { if (islower(cons[i])) { lc = 1; break; } } if (!lc) { free(el); return; } } // Remove any older items on the list that are entirely contained within el if (*list) { tmp = DL_TAIL(*list); do { prev = tmp->prev; if (tmp->end < el->start) break; if (tmp->start >= el->start) { DL_DELETE(*list, tmp); free(tmp); } if (tmp == DL_HEAD(*list)) break; tmp = prev; } while (*list); } DL_APPEND(*list, el); return; } /* * Finds repeated homopolymers up to 8-mers. * Note this assumes cons is 0-3, so N of 4 may rarely give false hits. * * Returns a list of rep_ele structs holding the start,end tuples of repeats; * NULL on failure. */ rep_ele *find_STR64(char *cons, int len, int lower_only) { int i, j; uint64_t w = 0; rep_ele *reps = NULL; for (i = j = 0; i < len && j < 26; i++) { if (cons[i] == '*') continue; w <<= 2; w |= cons[i]; //printf("%3d %c w=%08x\n", i, cons[i], w); if (j>= 1 && (w&0x0003) == ((w>> 2)&0x0003)) add_rep(&reps, cons, len, i, 1, lower_only, w); if (j>= 3 && (w&0x000f) == ((w>> 4)&0x000f)) add_rep(&reps, cons, len, i, 2, lower_only, w); if (j>= 5 && (w&0x003f) == ((w>> 6)&0x003f)) add_rep(&reps, cons, len, i, 3, lower_only, w); if (j>= 7 && (w&0x00ff) == ((w>> 8)&0x00ff)) add_rep(&reps, cons, len, i, 4, lower_only, w); if (j>= 9 && (w&0x03ff) == ((w>>10)&0x03ff)) add_rep(&reps, cons, len, i, 5, lower_only, w); if (j>=11 && (w&0x0fff) == ((w>>12)&0x0fff)) add_rep(&reps, cons, len, i, 6, lower_only, w); if (j>=13 && (w&0x3fff) == ((w>>14)&0x3fff)) add_rep(&reps, cons, len, i, 7, lower_only, w); if (j>=15 && (w&0xffff) == ((w>>16)&0xffff)) add_rep(&reps, cons, len, i, 8, lower_only, w); if (j>=17 && (w&0x003ffff) == ((w>>18)&0x003ffff)) add_rep(&reps, cons, len, i, 9, lower_only, w); if (j>=19 && (w&0x00fffff) == ((w>>20)&0x00fffff)) add_rep(&reps, cons, len, i,10, lower_only, w); if (j>=21 && (w&0x03fffff) == ((w>>22)&0x03fffff)) add_rep(&reps, cons, len, i,11, lower_only, w); if (j>=23 && (w&0x0ffffff) == ((w>>24)&0x0ffffff)) add_rep(&reps, cons, len, i,12, lower_only, w); if (j>=24 && (w&0x3ffffff) == ((w>>26)&0x3ffffff)) add_rep(&reps, cons, len, i,13, lower_only, w); j++; } for (; i < len; i++) { if (cons[i] == '*') continue; w <<= 2; w |= cons[i]; //printf("%3d %c w=%08x\n", i, cons[i], w); if ((w&0xfffffff) == ((w>>28)&0xfffffff)) add_rep(&reps, cons, len, i, 14, lower_only, w); else if ((w&0x3ffffff) == ((w>>26)&0x3ffffff)) add_rep(&reps, cons, len, i, 13, lower_only, w); else if ((w&0x0ffffff) == ((w>>24)&0x0ffffff)) add_rep(&reps, cons, len, i, 12, lower_only, w); else if ((w&0x03fffff) == ((w>>22)&0x03fffff)) add_rep(&reps, cons, len, i, 11, lower_only, w); else if ((w&0x00fffff) == ((w>>20)&0x00fffff)) add_rep(&reps, cons, len, i, 10, lower_only, w); else if ((w&0x003ffff) == ((w>>18)&0x003ffff)) add_rep(&reps, cons, len, i, 9, lower_only, w); else if ((w&0xffff) == ((w>>16)&0xffff)) add_rep(&reps, cons, len, i, 8, lower_only, w); else if ((w&0x3fff) == ((w>>14)&0x3fff)) add_rep(&reps, cons, len, i, 7, lower_only, w); else if ((w&0x0fff) == ((w>>12)&0x0fff)) add_rep(&reps, cons, len, i, 6, lower_only, w); else if ((w&0x03ff) == ((w>>10)&0x03ff)) add_rep(&reps, cons, len, i, 5, lower_only, w); else if ((w&0x00ff) == ((w>> 8)&0x00ff)) add_rep(&reps, cons, len, i, 4, lower_only, w); else if ((w&0x003f) == ((w>> 6)&0x003f)) add_rep(&reps, cons, len, i, 3, lower_only, w); else if ((w&0x000f) == ((w>> 4)&0x000f)) add_rep(&reps, cons, len, i, 2, lower_only, w); else if ((w&0x0003) == ((w>> 2)&0x0003)) add_rep(&reps, cons, len, i, 1, lower_only, w); } return reps; } rep_ele *find_STR(char *cons, int len, int lower_only) { int i, j; uint32_t w = 0; rep_ele *reps = NULL; for (i = j = 0; i < len && j < 15; i++) { if (cons[i] == '*') continue; w <<= 2; w |= cons[i]; //printf("%3d %c w=%08x\n", i, cons[i], w); if (j>= 1 && (w&0x0003) == ((w>> 2)&0x0003)) add_rep(&reps, cons, len, i, 1, lower_only, w); if (j>= 3 && (w&0x000f) == ((w>> 4)&0x000f)) add_rep(&reps, cons, len, i, 2, lower_only, w); if (j>= 5 && (w&0x003f) == ((w>> 6)&0x003f)) add_rep(&reps, cons, len, i, 3, lower_only, w); if (j>= 7 && (w&0x00ff) == ((w>> 8)&0x00ff)) add_rep(&reps, cons, len, i, 4, lower_only, w); if (j>= 9 && (w&0x03ff) == ((w>>10)&0x03ff)) add_rep(&reps, cons, len, i, 5, lower_only, w); if (j>=11 && (w&0x0fff) == ((w>>12)&0x0fff)) add_rep(&reps, cons, len, i, 6, lower_only, w); if (j>=13 && (w&0x3fff) == ((w>>14)&0x3fff)) add_rep(&reps, cons, len, i, 7, lower_only, w); j++; } for (; i < len; i++) { if (cons[i] == '*') continue; w <<= 2; w |= cons[i]; //printf("%3d %c w=%08x\n", i, cons[i], w); if ((w&0xffff) == ((w>>16)&0xffff)) add_rep(&reps, cons, len, i, 8, lower_only, w); else if ((w&0x3fff) == ((w>>14)&0x3fff)) add_rep(&reps, cons, len, i, 7, lower_only, w); else if ((w&0x0fff) == ((w>>12)&0x0fff)) add_rep(&reps, cons, len, i, 6, lower_only, w); else if ((w&0x03ff) == ((w>>10)&0x03ff)) add_rep(&reps, cons, len, i, 5, lower_only, w); else if ((w&0x00ff) == ((w>> 8)&0x00ff)) add_rep(&reps, cons, len, i, 4, lower_only, w); else if ((w&0x003f) == ((w>> 6)&0x003f)) add_rep(&reps, cons, len, i, 3, lower_only, w); else if ((w&0x000f) == ((w>> 4)&0x000f)) add_rep(&reps, cons, len, i, 2, lower_only, w); else if ((w&0x0003) == ((w>> 2)&0x0003)) add_rep(&reps, cons, len, i, 1, lower_only, w); } return reps; } /* ----------------------------------------------------------------------------- * Computes repeat regions in the consensus and then provides a bit mask * indicating the extend of the STRs. * * The purpose of this is to identify where a read needs to span the entire * region in order to validate how many copies of a repeat word are present. * This only really has a major impact when indels are involved. * * For example, given this multiple alignment: * * S1 GATCGGACGAGAG * S2 GATCGGACGAGAGAGAGAGAGT * S3 GATCGGACGAGAGAGAGAG**TCGGAC * S4 GGACGAGAGAGAGAGAGTCGGAC * S5 CGAGAGAGAGAG**TCGGAC * S6 AGAGAGAGTCGGAC * * We have subseq of GAGAGAGAGAG** vs GAGAGAGAGAGAG. The first and last * (S1 and S6) sequences do not span and so we do not know which allele they * match. Specifically as the pad is at the right hand end, the alignment of * S6 gives incorrect weight to the consensus as it is stating AG when it * may actually be ** at that point. * * By identifying the repeats we can soft clip as follows: * * S1 GATCGGACgagag * S2 GATCGGACGAGAGAGAGAGAGT * S3 GATCGGACGAGAGAGAGAG**TCGGAC * S4 GGACGAGAGAGAGAGAGTCGGAC * S5 CGAGAGAGAGAG**TCGGAC * S6 agagagagTCGGAC * * Returns an array of STR vs no-STR values. * 0 => non repetitive. * 1+ => repeat with consecutive bit-number for repeat size. * * Eg: AGGGGAGGAGAAGAC * 1111 1111 * 2222222 * 444444 * => 011331137754440 */ char *cons_mark_STR(char *cons, int len, int lower_only) { rep_ele *reps, *elt, *tmp; char *str; str = calloc(1, len); reps = find_STR(cons, len, lower_only); DL_FOREACH_SAFE(reps, elt, tmp) { int i, v = 0; //printf("%2d .. %2d %.*s\n", elt->start, elt->end, // elt->end - elt->start+1, &cons[elt->start]); // What is there? for (i = MAX(elt->start-1,0); i <= MIN(elt->end+1,len-1); i++) v |= str[i]; for (i = 0; i < 8; i++) { if (!(v&(1<start; i <= elt->end; i++) str[i] |= v; DL_DELETE(reps, elt); free(elt); } return str; } bcftools-1.21/str_finder.h000066400000000000000000000045541467060157400156020ustar00rootroot00000000000000/* str_finder.c -- Short Tandem Repeat finder. Originally from Crumble (https://github.com/jkbonfield/crumble) Copyright (C) 2015-2016, 2021, 2023 Genome Research Ltd. Author: James Bonfield Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef _STR_FINDER_H_ #define _STR_FINDER_H_ #include "utlist.h" typedef struct rep_ele { int start, end, rep_len; struct rep_ele *prev; struct rep_ele *next; } rep_ele; /* * Finds repeated homopolymers up to 8-mers. * * If lower_only is true then it only adds STRs for regions that * contain at least one lower-case base. This can be used as a marker * for looking for specific types of repeats. * (One use for this is to only mark STRs that overlap a heterozygous * indel region.) * * Returns a list of rep_ele structs holding the start,end tuples of repeats; * NULL on failure. */ rep_ele *find_STR(char *cons, int len, int lower_only); /* As above, but use a longer hash with longer STR elements found */ rep_ele *find_STR64(char *cons, int len, int lower_only); /* * Returns an array of STR vs no-STR values. * 0 => non repetitive. * 1+ => repeat with consecutive bit-number for repeat size. * * Eg: AGGGGAGGAGAAGAC * 1111 1111 * 2222222 * 444444 * => 011331137754440 */ char *cons_mark_STR(char *cons, int len, int lower_only); #endif /* _STR_FINDER_H_ */ bcftools-1.21/tabix.c000066400000000000000000000131001467060157400145300ustar00rootroot00000000000000/* tabix.c -- tabix subcommand. Copyright (C) 2012 Broad Institute. Copyright (C) 2013, 2016 Genome Research Ltd. Author: Heng Li Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include int main_tabix(int argc, char *argv[]) { int c, min_shift = -1, is_force = 0, is_all = 0, detect = 1; tbx_conf_t conf = tbx_conf_gff; while ((c = getopt(argc, argv, "0fap:s:b:e:S:c:m:")) >= 0) if (c == '0') conf.preset |= TBX_UCSC; else if (c == 'f') is_force = 1; else if (c == 'a') is_all = 1; else if (c == 'm') min_shift = atoi(optarg); else if (c == 's') conf.sc = atoi(optarg); else if (c == 'b') conf.bc = atoi(optarg); else if (c == 'e') conf.ec = atoi(optarg); else if (c == 'c') conf.meta_char = *optarg; else if (c == 'S') conf.line_skip = atoi(optarg); else if (c == 'p') { if (strcmp(optarg, "gff") == 0) conf = tbx_conf_gff; else if (strcmp(optarg, "bed") == 0) conf = tbx_conf_bed; else if (strcmp(optarg, "sam") == 0) conf = tbx_conf_sam; else if (strcmp(optarg, "vcf") == 0) conf = tbx_conf_vcf; else { fprintf(stderr, "The type '%s' not recognised\n", optarg); return 1; detect = 0; } } if (optind == argc) { fprintf(stderr, "\nUsage: bcftools tabix [options] [reg1 [...]]\n\n"); fprintf(stderr, "Options: -p STR preset: gff, bed, sam or vcf [gff]\n"); fprintf(stderr, " -s INT column number for sequence names (suppressed by -p) [1]\n"); fprintf(stderr, " -b INT column number for region start [4]\n"); fprintf(stderr, " -e INT column number for region end (if no end, set INT to -b) [5]\n"); fprintf(stderr, " -0 specify coordinates are zero-based\n"); fprintf(stderr, " -S INT skip first INT lines [0]\n"); fprintf(stderr, " -c CHAR skip lines starting with CHAR [null]\n"); fprintf(stderr, " -a print all records\n"); fprintf(stderr, " -f force to overwrite existing index\n"); fprintf(stderr, " -m INT set the minimal interval size to 1<= 0) puts(s.s); bgzf_close(fp); free(s.s); } else if (optind + 2 > argc) { // create index if ( detect ) { // auto-detect file type by file name int l = strlen(argv[optind]); if (l>=7 && strcasecmp(argv[optind]+l-7, ".gff.gz") == 0) conf = tbx_conf_gff; else if (l>=7 && strcasecmp(argv[optind]+l-7, ".bed.gz") == 0) conf = tbx_conf_bed; else if (l>=7 && strcasecmp(argv[optind]+l-7, ".sam.gz") == 0) conf = tbx_conf_sam; else if (l>=7 && strcasecmp(argv[optind]+l-7, ".vcf.gz") == 0) conf = tbx_conf_vcf; } if (!is_force) { char *fn; FILE *fp; fn = (char*)malloc(strlen(argv[optind]) + 5); strcat(strcpy(fn, argv[optind]), min_shift <= 0? ".tbi" : ".csi"); if ((fp = fopen(fn, "rb")) != 0) { fclose(fp); free(fn); fprintf(stderr, "[E::%s] the index file exists; use option '-f' to overwrite\n", __func__); return 1; } free(fn); } if ( tbx_index_build(argv[optind], min_shift, &conf) ) { fprintf(stderr,"tbx_index_build failed: Is the file bgzip-compressed? Was wrong -p [type] option used?\n"); return 1; } } else { // read with random access tbx_t *tbx; BGZF *fp; kstring_t s; int i; if ((tbx = tbx_index_load(argv[optind])) == 0) return 1; if ((fp = bgzf_open(argv[optind], "r")) == 0) return 1; s.s = 0; s.l = s.m = 0; for (i = optind + 1; i < argc; ++i) { hts_itr_t *itr; if ((itr = tbx_itr_querys(tbx, argv[i])) == 0) continue; while (tbx_bgzf_itr_next(fp, tbx, itr, &s) >= 0) puts(s.s); tbx_itr_destroy(itr); } free(s.s); bgzf_close(fp); tbx_destroy(tbx); } return 0; } bcftools-1.21/test/000077500000000000000000000000001467060157400142415ustar00rootroot00000000000000bcftools-1.21/test/23andme.fa000066400000000000000000000004371467060157400160060ustar00rootroot00000000000000>1 CACGTNACGGCTGAAGTCCAAGGTAC CGTATCGAGTTCACAGTCGATAGCTC GATCGATAGCATCGCTAGCNNNACTA CGATCGATCGCTCTCCGTAACACTCA AAAACGATCGATCGACTGCTCTTTAG CGATGACTTTAGGGGAAAAA >2 CGCTCAGCCGTACAGCCGAGCAGGAC ACGCTATTTTAGATCGACTGGCTNNG CGCTAGCTACGCTTTAGCACGAGAA >Y NNNGCATACGTGTCCATCACGATGAT AGCGATGATCGATC bcftools-1.21/test/aa.2.out000066400000000000000000000022461467060157400155170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 105 . NNNNNNNNN T,TAACCCTA 999 PASS . 2 1 . AGCACCTGCCTCCAGGGCGACTGCGACTCCGTGCTGCTCTCCCTGGGAGGCCCTGTTCCTGTCCATGTGGCCCGTGCTGGTGTGACAGTGGGAGGACAGAGATCTGTGGGAATGCCGTGCACCCGGCAGATGCTGTGTGCACCTGGCGGGGGGTTCGTGCCTGAGCTGCTGTAGGGTGAAGCTGCAGTTTC ACG 999 PASS . 2 101 . G ATT 999 PASS . 2 114 . G TTC,TT 999 PASS . 2 115 . C T 999 PASS . 20 3 . G CT 999 PASS . 20 5 . TG CT 999 PASS . 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . 20 59 . AG . 999 PASS . 20 81 . A C 999 PASS . 20 84 . T T 999 PASS . 20 95 . T A 999 PASS . 20 95 . TCACCG AAAAAA 999 PASS . 20 273 . C CAA,CAAA 999 PASS . 20 273 . C CAAAAAAAAAA 999 PASS . 20 273 . C CAA 999 PASS . 20 275 . A C,G 999 PASS . 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . 3 17 . CA C 999 PASS . 4 36 . TC C,TT,TTC 999 PASS . 5 21 . A AAG 999 PASS . bcftools-1.21/test/aa.fa000066400000000000000000000021441467060157400151330ustar00rootroot00000000000000>20 AGGATGGGGCTCATTAATAGAGCTCCACTTGTCTCCAGAATCACTGGTGAGGAAGGGGAG TGTTGCCCCCACATTcGTGCACATCAGGGATGGTTCACCGAACTCCACACCAGTCTCTGc AGAGCCTGTTGGGGAGAGGAGGGCTGTGGCTTCTTTGATGGTGTTCACCTGGAGTAGAGC AAGTATTGTCAAAAGGGTCATCCTCGGAGGTTGCAGTGAGCCGAGATCGCACCATTGCAC TGCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAaAAAaAaAAAaAAAAAGGCCAT C >1 ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ . >2 2:1382388-1382602 AGCACCTGCCTCCAGGGCGACTGCGACTCCGTGCTGCTCTCCCTGGGAGGCCCTGTTCCT GTCCAtGTGGCCCGTGCTGGTGTGACAGTGGGAGGACAGAGATCTGTgGGAATGCCGTGC ACCCGGCAGATGCTGTGTGCACCTGGCGGGgGGTTCgTgCCTGAGCTGCTGTAGgGTGAA GCTGCAGTTTCAGAAGGTCCGAGAGATGTTAAACC >3 ACTGGACACGTGGACACACACACACACACACACACACACACAGTCAAACCACCTACCAGA >4 TCCCCTCTTGACCTCcCTCTATTTTTT..TTTTTTTCTGAGATGGATTTTTGCTCTTGTT >5 GTCTCAAAAAAAAAAAAAAAAAAAAGAAAAG >21 TTTATTATtAGTAttaTTAAATTGAATTTATTTAGTGTACATACATTCATGTGTATTGTG >22 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN bcftools-1.21/test/aa.hdr000066400000000000000000000001031467060157400153130ustar00rootroot00000000000000##INFO= bcftools-1.21/test/aa.out000066400000000000000000000023701467060157400153550ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 105 . TAAACCCTA T,TAACCCTA 999 PASS . 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . 2 101 . A ATT 999 PASS . 2 114 . T TTC,TT 999 PASS . 2 115 . C T 999 PASS AA=C 20 3 . G CT 999 PASS . 20 5 . TG CT 999 PASS . 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . 20 59 . AG . 999 PASS . 20 81 . A C 999 PASS AA=A 20 84 . G T 999 PASS AA=T 20 95 . T A 999 PASS AA=T 20 95 . TCACCG AAAAAA 999 PASS . 20 273 . C CAA,CAAA 999 PASS . 20 273 . C CAAAAAAAAAA 999 PASS . 20 273 . C CAA 999 PASS . 20 275 . A C,G 999 PASS AA=A 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . 3 17 . CA C 999 PASS . 4 36 . TC C,TT,TTC 999 PASS . 5 21 . A AAG 999 PASS . bcftools-1.21/test/aa.vcf000066400000000000000000000022461467060157400153260ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 105 . TAAACCCTA T,TAACCCTA 999 PASS . 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . 2 101 . A ATT 999 PASS . 2 114 . T TTC,TT 999 PASS . 2 115 . C T 999 PASS . 20 3 . G CT 999 PASS . 20 5 . TG CT 999 PASS . 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . 20 59 . AG . 999 PASS . 20 81 . A C 999 PASS . 20 84 . G T 999 PASS . 20 95 . T A 999 PASS . 20 95 . TCACCG AAAAAA 999 PASS . 20 273 . C CAA,CAAA 999 PASS . 20 273 . C CAAAAAAAAAA 999 PASS . 20 273 . C CAA 999 PASS . 20 275 . A C,G 999 PASS . 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . 3 17 . CA C 999 PASS . 4 36 . TC C,TT,TTC 999 PASS . 5 21 . A AAG 999 PASS . bcftools-1.21/test/ad-bias.2.out000066400000000000000000000025131467060157400164330ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 22 16051249 . T C 32.1761 . . GT:AD 0/1:4,3 0/0:41,0 0/0:55,0 22 16051347 . G C 283 . . GT:AD 1/1:2,4 0/1:20,20 0/0:43,0 22 16051453 . A C 3.42882 . . GT:AD 0/1:5,4 0/0:39,0 0/0:47,0 22 16051497 . A G 362 . . GT:AD 1/1:0,8 0/1:14,20 0/0:44,0 22 16053659 . A C 352 . . GT:AD 1/1:0,9 1/1:0,21 0/0:30,0 22 16053791 . C A 287 . . GT:AD 0/1:4,4 0/1:13,16 0/0:32,0 22 16055942 . C T 385 . . GT:AD 1/1:0,7 1/1:0,22 0/0:31,0 22 16056126 . G A 263 . . GT:AD 0/1:2,6 0/1:12,16 0/0:27,0 22 16058415 . A G 212 . . GT:AD 0/0:9,0 1/1:0,37 0/0:35,2 22 16058463 . C T 136 . . GT:AD 0/1:1,8 0/0:40,0 0/0:45,0 22 16058758 . C A 107 . . GT:AD 1/1:2,8 0/0:19,0 0/0:34,0 22 16058766 . G A 15.517 . . GT:AD 0/0:11,0 1/1:0,4 0/0:32,0 22 16058852 . A T 198 . . GT:AD 1/1:0,3 1/1:0,19 0/0:36,0 22 16059081 . A G 212 . . GT:AD 0/0:6,0 1/1:0,35 0/0:35,0 22 16059734 . C T 114 . . GT:AD 1/1:1,9 0/0:23,0 0/0:31,0 22 16059753 . A T 212 . . GT:AD 0/0:9,0 1/1:0,19 0/0:28,0 22 16060178 . G A 187 . . GT:AD 0/0:5,0 1/1:1,20 0/0:36,0 bcftools-1.21/test/ad-bias.2.vcf000066400000000000000000000051471467060157400164100ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 22 16050159 . C T 68 . . GT:AD 0/0:4,0 0/1:6,8 0/0:26,0 22 16050252 . A T 85 . . GT:AD 0/0:3,0 0/1:13,13 0/0:40,0 22 16051249 . T C,A 32.1761 . . GT:AD 0/1:4,3,1 0/0:41,0,1 0/0:55,0,1 22 16051347 . G C,A 283 . . GT:AD 1/1:2,4,1 0/1:20,20,1 0/0:43,0,1 22 16051453 . A C,T 3.42882 . . GT:AD 0/1:5,4,1 0/0:39,0,1 0/0:47,0,1 22 16051497 . A G,T 362 . . GT:AD 1/1:0,8,1 0/1:14,20,1 0/0:44,0,1 22 16051968 . C A 136 . . GT:AD 0/0:4,0 0/1:11,11 0/0:13,0 22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GT:AD ./.:0,0 1/1:0,27 0/0:46,0 22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GT:AD 0/1:1,1 0/1:7,29 0/0:54,0 22 16052180 . AAAC AAACCAACTAAC 221 . . GT:AD 0/0:2,0 0/1:16,15 0/0:55,0 22 16052239 . A G 172 . . GT:AD 0/0:5,0 0/1:12,17 0/0:44,0 22 16052513 . G C 153 . . GT:AD 0/0:11,0 0/1:25,16 0/0:38,0 22 16052618 . G A 124 . . GT:AD 0/0:7,0 0/1:29,12 0/0:41,0 22 16053659 . A C,T 352 . . GT:AD 1/1:0,9,1 1/1:0,21,1 0/0:30,0,1 22 16053791 . C A,T 287 . . GT:AD 0/1:4,4,1 0/1:13,16,1 0/0:32,0,1 22 16054454 . C T 14.2772 . . GT:AD 0/1:2,2 0/0:34,0 0/0:31,0 22 16054667 . C G 179 . . GT:AD 0/0:8,0 0/1:12,15 0/0:27,0 22 16054740 . A G 126 . . GT:AD 0/0:6,0 0/1:11,16 0/0:26,0 22 16055942 . C A,T 385 . . GT:AD 2/2:0,1,7 2/2:0,1,22 0/0:31,1,0 22 16056126 . G T,A,C 263 . . GT:AD 0/2:2,1,6,1 0/2:12,1,16,1 0/0:27,1,0,1 22 16056854 . G GA 17.3105 . . GT:AD 0/0:7,0 0/1:11,15 0/0:35,0 22 16057248 . G A 167 . . GT:AD 0/0:5,0 0/1:15,14 0/0:32,0 22 16057320 . G A 20.0168 . . GT:AD 0/1:2,2 0/0:25,0 0/0:36,0 22 16057417 . C T 16.3704 . . GT:AD 0/1:2,2 0/0:36,0 0/0:25,0 22 16058070 . A G 452 . . GT:AD 1/1:0,4 1/1:0,21 1/1:0,22 22 16058415 . A G 212 . . GT:AD 0/0:9,0 1/1:0,37 0/0:35,2 22 16058463 . C T 136 . . GT:AD 0/1:1,8 0/0:40,0 0/0:45,0 22 16058758 . C A 107 . . GT:AD 1/1:2,8 0/0:19,0 0/0:34,0 22 16058766 . G A 15.517 . . GT:AD 0/0:11,0 1/1:0,4 0/0:32,0 22 16058852 . A T 198 . . GT:AD 1/1:0,3 1/1:0,19 0/0:36,0 22 16058883 . A G 129 . . GT:AD 1/1:0,1 1/1:0,18 0/0:36,0 22 16059081 . A G 212 . . GT:AD 0/0:6,0 1/1:0,35 0/0:35,0 22 16059734 . C T 114 . . GT:AD 1/1:1,9 0/0:23,0 0/0:31,0 22 16059753 . A T 212 . . GT:AD 0/0:9,0 1/1:0,19 0/0:28,0 22 16059973 . C A 195 . . GT:AD 0/0:4,0 0/0:21,0 0/1:21,18 22 16060178 . G A 187 . . GT:AD 0/0:5,0 1/1:1,20 0/0:36,0 bcftools-1.21/test/ad-bias.out000066400000000000000000000026771467060157400163060ustar00rootroot00000000000000# # FT, Fisher Test [2]Sample [3]Control [4]Chrom [5]Pos [6]REF [7]ALT [8]smpl.nREF [9]smpl.nALT [10]ctrl.nREF [11]ctrl.nALT [12]P-value FT NA12890 NA12892 22 16051249 T C 4 3 55 0 9.254363e-04 FT NA12890 NA12892 22 16051347 G C 2 4 43 0 7.079613e-05 FT NA12890 NA12891 22 16051453 A C 5 4 39 0 6.475486e-04 FT NA12890 NA12892 22 16051453 A C 5 4 47 0 3.430532e-04 FT NA12890 NA12892 22 16051497 A G 0 8 44 0 1.328836e-09 FT NA12890 NA12892 22 16053659 A C 0 9 30 0 4.718870e-09 FT NA12890 NA12892 22 16053791 C A 4 4 32 0 7.659481e-04 FT NA12890 NA12892 22 16055942 C T 0 7 31 0 7.923770e-08 FT NA12890 NA12892 22 16056126 G A 2 6 27 0 1.725030e-05 FT NA12890 NA12891 22 16058415 A G 9 0 0 37 9.076747e-10 FT NA12890 NA12891 22 16058463 C T 1 8 40 0 1.995662e-08 FT NA12890 NA12892 22 16058463 C T 1 8 45 0 8.649972e-09 FT NA12890 NA12891 22 16058758 C A 2 8 19 0 1.048427e-05 FT NA12890 NA12892 22 16058758 C A 2 8 34 0 2.539036e-07 FT NA12890 NA12891 22 16058766 G A 11 0 0 4 7.326007e-04 FT NA12890 NA12892 22 16058852 A T 0 3 36 0 1.094212e-04 FT NA12890 NA12891 22 16059081 A G 6 0 0 35 2.224007e-07 FT NA12890 NA12891 22 16059734 C T 1 9 23 0 2.592884e-07 FT NA12890 NA12892 22 16059734 C T 1 9 31 0 2.854341e-08 FT NA12890 NA12891 22 16059753 A T 9 0 0 19 1.447828e-07 FT NA12890 NA12891 22 16060178 G A 5 0 1 20 9.121313e-05 # SN, Summary Numbers [2]Number of Pairs [3]Number of Sites [4]Number of comparisons [5]P-value output threshold SN 2 36 54 1.000000e-03 bcftools-1.21/test/ad-bias.samples000066400000000000000000000000401467060157400171210ustar00rootroot00000000000000NA12890 NA12891 NA12890 NA12892 bcftools-1.21/test/ad-bias.vcf000066400000000000000000000050371467060157400162460ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 22 16050159 . C T 68 . . GT:AD 0/0:4,0 0/1:6,8 0/0:26,0 22 16050252 . A T 85 . . GT:AD 0/0:3,0 0/1:13,13 0/0:40,0 22 16051249 . T C 32.1761 . . GT:AD 0/1:4,3 0/0:41,0 0/0:55,0 22 16051347 . G C 283 . . GT:AD 1/1:2,4 0/1:20,20 0/0:43,0 22 16051453 . A C 3.42882 . . GT:AD 0/1:5,4 0/0:39,0 0/0:47,0 22 16051497 . A G 362 . . GT:AD 1/1:0,8 0/1:14,20 0/0:44,0 22 16051968 . C A 136 . . GT:AD 0/0:4,0 0/1:11,11 0/0:13,0 22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GT:AD ./.:0,0 1/1:0,27 0/0:46,0 22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GT:AD 0/1:1,1 0/1:7,29 0/0:54,0 22 16052180 . AAAC AAACCAACTAAC 221 . . GT:AD 0/0:2,0 0/1:16,15 0/0:55,0 22 16052239 . A G 172 . . GT:AD 0/0:5,0 0/1:12,17 0/0:44,0 22 16052513 . G C 153 . . GT:AD 0/0:11,0 0/1:25,16 0/0:38,0 22 16052618 . G A 124 . . GT:AD 0/0:7,0 0/1:29,12 0/0:41,0 22 16053659 . A C 352 . . GT:AD 1/1:0,9 1/1:0,21 0/0:30,0 22 16053791 . C A 287 . . GT:AD 0/1:4,4 0/1:13,16 0/0:32,0 22 16054454 . C T 14.2772 . . GT:AD 0/1:2,2 0/0:34,0 0/0:31,0 22 16054667 . C G 179 . . GT:AD 0/0:8,0 0/1:12,15 0/0:27,0 22 16054740 . A G 126 . . GT:AD 0/0:6,0 0/1:11,16 0/0:26,0 22 16055942 . C T 385 . . GT:AD 1/1:0,7 1/1:0,22 0/0:31,0 22 16056126 . G A 263 . . GT:AD 0/1:2,6 0/1:12,16 0/0:27,0 22 16056854 . G GA 17.3105 . . GT:AD 0/0:7,0 0/1:11,15 0/0:35,0 22 16057248 . G A 167 . . GT:AD 0/0:5,0 0/1:15,14 0/0:32,0 22 16057320 . G A 20.0168 . . GT:AD 0/1:2,2 0/0:25,0 0/0:36,0 22 16057417 . C T 16.3704 . . GT:AD 0/1:2,2 0/0:36,0 0/0:25,0 22 16058070 . A G 452 . . GT:AD 1/1:0,4 1/1:0,21 1/1:0,22 22 16058415 . A G 212 . . GT:AD 0/0:9,0 1/1:0,37 0/0:35,2 22 16058463 . C T 136 . . GT:AD 0/1:1,8 0/0:40,0 0/0:45,0 22 16058758 . C A 107 . . GT:AD 1/1:2,8 0/0:19,0 0/0:34,0 22 16058766 . G A 15.517 . . GT:AD 0/0:11,0 1/1:0,4 0/0:32,0 22 16058852 . A T 198 . . GT:AD 1/1:0,3 1/1:0,19 0/0:36,0 22 16058883 . A G 129 . . GT:AD 1/1:0,1 1/1:0,18 0/0:36,0 22 16059081 . A G 212 . . GT:AD 0/0:6,0 1/1:0,35 0/0:35,0 22 16059734 . C T 114 . . GT:AD 1/1:1,9 0/0:23,0 0/0:31,0 22 16059753 . A T 212 . . GT:AD 0/0:9,0 1/1:0,19 0/0:28,0 22 16059973 . C A 195 . . GT:AD 0/0:4,0 0/0:21,0 0/1:21,18 22 16060178 . G A 187 . . GT:AD 0/0:5,0 1/1:1,20 0/0:36,0 bcftools-1.21/test/af-dist.out000066400000000000000000000013511467060157400163210ustar00rootroot00000000000000# # PROB_DIST, genotype probability distribution, assumes HWE PROB_DIST 0.000000 0.100000 0 PROB_DIST 0.100000 0.200000 0 PROB_DIST 0.200000 0.300000 1 PROB_DIST 0.300000 0.400000 0 PROB_DIST 0.400000 0.500000 14 PROB_DIST 0.500000 0.600000 2 PROB_DIST 0.600000 0.700000 2 PROB_DIST 0.700000 0.800000 0 PROB_DIST 0.800000 0.900000 0 PROB_DIST 0.900000 1.000000 0 # DEV_DIST, distribution of AF deviation, based on AF and INFO/AN, AC calculated on the fly DEV_DIST 0.000000 0.100000 7 DEV_DIST 0.100000 0.200000 0 DEV_DIST 0.200000 0.300000 0 DEV_DIST 0.300000 0.400000 0 DEV_DIST 0.400000 0.500000 0 DEV_DIST 0.500000 0.600000 0 DEV_DIST 0.600000 0.700000 0 DEV_DIST 0.700000 0.800000 0 DEV_DIST 0.800000 0.900000 0 DEV_DIST 0.900000 1.000000 0 bcftools-1.21/test/af-dist.vcf000066400000000000000000000021271467060157400162720ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##FORMAT= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 . AN=6 GT 0/0 0/0 0/0 11 5464562 . C T 999 . AN=0;AC=0 GT ./. ./. ./. 20 76962 rs6111385 T C 999 . AN=6;AF=0.833333;AC=5 GT 0/1 1/1 1/1 20 126310 . ACC A 999 . AN=6;AF=0.666667;AC=4 GT 0/1 0/1 1/1 20 138125 rs2298108 G T 999 . AN=6;AF=0.666667;AC=4 GT 0/1 0/1 1/1 20 138148 rs2298109 C T 999 . AN=6;AF=0.666667;AC=4 GT 0/1 0/1 1/1 20 271225 . T TTTA,TA 999 . AN=6;AF=0.333333,0.333333;AC=2,2 GT 0/2 0/1 1/2 20 304568 . C T 999 . AN=6;AF=0.666667;AC=4 GT 0|1 0|1 1|1 20 326891 . A AC 999 . AN=4;AF=0.5;AC=2 GT 0|1 0|1 ./. bcftools-1.21/test/annotate.32.out000066400000000000000000000011721467060157400170270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##ALT= ##ALT= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 54713 . N . PASS END=54714;EVIDENCE=RD,PE,SR chr1 66224 . N . PASS END=66275;EVIDENCE=RD,PE,SR chr1 66242 . N . PASS END=66520;EVIDENCE=RD,PE,SR chr1 998763 . N . PASS END=998764;EVIDENCE=RD,PE,SR bcftools-1.21/test/annotate.33.out000066400000000000000000000054551467060157400170400ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS AN=4;AC=2;XXX GT:GQ 0/1:245 0/1:245 1 3000151 . C T 59.2 PASS AN=4;AC=2;XXX GT:DP:GQ 0/1:32:245 0/1:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test;XXX GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1;XXX GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS AN=4;AC=2;XXX GT:GQ:DP 0/1:245:32 0/1:245:32 1 3106154 . C CT 59.2 PASS AN=4;AC=2;XXX GT:GQ:DP 0/1:245:32 0/1:245:32 1 3157410 . GA G 90.6 q10 AN=4;AC=4;XXX GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS AN=4;AC=2;XXX GT:GQ:DP 0/1:212:22 0/1:212:22 1 3177144 . G T 45 PASS AN=4;AC=2;XXX GT:GQ:DP 0/0:150:30 1/1:150:30 1 3177144 . G . 45 PASS AN=4;AC=0;XXX GT:GQ:DP 0/0:150:30 0/0:150:30 1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2;XXX GT:GQ:DP 1/2:12:10 1/2:12:10 2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2;XXX GT:GQ:DP 1/2:322:26 1/2:322:26 3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2;XXX GT:GQ:DP 1/2:91:26 1/2:91:26 4 3258448 . TACACACAC T 59.9 PASS AN=4;AC=2;XXX GT:GQ:DP 0/1:325:31 0/1:325:31 4 4000000 . T A,C 59.9 PASS AN=4;AC=2,0;XXX GT:GQ:DP 0/1:325:31 0/1:325:31 4 4000001 . T A 59.9 PASS AN=4;AC=2;XXX GT:GQ:DP 0/1:325:31 0/1:325:31 bcftools-1.21/test/annotate.escape.1.1.out000066400000000000000000000005431467060157400203420ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##INFO= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl chr1 101 . C G . . ISTR=%3D_and_%_and_%3B_work FSTR %_and_=_and_%3A_work bcftools-1.21/test/annotate.escape.1.tab000066400000000000000000000000571467060157400201420ustar00rootroot00000000000000chr1 101 =_and_%_and_;_work %_and_=_and_:_work bcftools-1.21/test/annotate.escape.1.vcf000077500000000000000000000003771467060157400201620ustar00rootroot00000000000000##fileformat=VCFv4.3 ##INFO= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl chr1 101 . C G . . . . . bcftools-1.21/test/annotate.hdr000066400000000000000000000004031467060157400165460ustar00rootroot00000000000000##INFO= ##INFO= ##INFO= ##INFO= bcftools-1.21/test/annotate.id.1.out000066400000000000000000000005461467060157400173420ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##FORMAT= ##contig= ##reference=ref.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 50 id50 C G . . . GT 0/0 1 51 id51 C A . . . GT 0/0 1 52 id52 C T . . . GT 0/0 1 53 id53 C T . . . GT 0/1 bcftools-1.21/test/annotate.id.2.1.out000066400000000000000000000003641467060157400175000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=hg38.fa #CHROM POS ID REF ALT QUAL FILTER INFO chrM 10 . T . . . . chrM 73 existingID A T . . . chrM 146 rs370482130 T C . . . bcftools-1.21/test/annotate.id.2.2.out000066400000000000000000000003761467060157400175040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=hg38.fa #CHROM POS ID REF ALT QUAL FILTER INFO chrM 10 rs879233578 T . . . . chrM 73 existingID A T . . . chrM 146 rs370482130 T C . . . bcftools-1.21/test/annotate.id.2.out000066400000000000000000000005461467060157400173430ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##FORMAT= ##contig= ##reference=ref.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 50 id50 C G . . . GT 0/0 1 51 id51 C A . . . GT 0/0 1 52 id52 C T . . . GT 0/0 1 53 id53 C A . . . GT 0/1 bcftools-1.21/test/annotate.id.2.vcf000066400000000000000000000003001467060157400172760ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=hg38.fa #CHROM POS ID REF ALT QUAL FILTER INFO chrM 10 . T . . . . chrM 73 existingID A T . . . chrM 146 rs370482130 T C . . . bcftools-1.21/test/annotate.id.vcf000066400000000000000000000004621467060157400171470ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FORMAT= ##contig= ##reference=ref.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 50 id50 C . . . . GT 0/0 1 51 id51 C . . . . GT 0/0 1 52 id52 C . . . . GT 0/0 1 53 id53 C A . . . GT 0/1 bcftools-1.21/test/annotate.match.1.1.out000066400000000000000000000006341467060157400201770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A C . PASS STR=xx2;INT=22;FLT=2.2;SCORE=22 bcftools-1.21/test/annotate.match.1.2.out000066400000000000000000000006341467060157400202000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . PASS STR=aa1;INT=11;FLT=1.1;SCORE=11 bcftools-1.21/test/annotate.match.1.tab000066400000000000000000000001311467060157400177670ustar00rootroot00000000000000#CHROM POS REF ALT SCORE STR INT FLT chr1 10 A T 11 xx1 11 1.1 chr1 10 A T 22 xx2 22 2.2 bcftools-1.21/test/annotate.match.1.vcf000066400000000000000000000006131467060157400200040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A C . PASS STR=xx2;INT=22;FLT=2.2 chr1 10 . A T . PASS STR=aa1;INT=11;FLT=1.1 bcftools-1.21/test/annotate.missing-append.1.out000066400000000000000000000011741467060157400216620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 752566 . G A,*,C,T . . STR=GA,.,GC,G,.,T;INT=1,.,2,3,.,3;FLT=1.0,.,2.0,3.0,.,3.0 1 752566 . G A,C . . STR=GA,GC;INT=1,2;FLT=1.0,2.0 1 800000 . ACGTACGT TCGTACGT,ACGT . . STR=AT0,.;INT=0,.;FLT=0.0,. 1 800008 . C T . . . 1 800009 . C T . . . 1 800100 . ACGT ACC,TCGT,AC . . STR=.,AT,.;INT=.,1,.;FLT=.,1.0,. bcftools-1.21/test/annotate.missing-append.tab000066400000000000000000000004561467060157400214640ustar00rootroot000000000000001 752566 G * . . . 1 752566 G T G,.,T 3,.,3 3.0,.,3.0 1 752566 G C GC 2 2.0 1 752566 G A GA 1 1.0 1 800000 A C AC0 0 0.0 1 800000 A T AT0 0 0.0 1 800000 A G AG0 0 0.0 1 800004 A C AC4 4 4.0 1 800004 A T AT4 4 4.0 1 800004 A G AG4 4 4.0 1 800100 A C AC 1 1.0 1 800100 A T AT 1 1.0 1 800100 A G AG 1 1.0 bcftools-1.21/test/annotate.missing-append.vcf000066400000000000000000000006731467060157400214750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 752566 . G A,*,C,T . . . 1 752566 . G A,C . . . 1 800000 . ACGTACGT TCGTACGT,ACGT . . . 1 800008 . C T . . . 1 800009 . C T . . . 1 800100 . ACGT ACC,TCGT,AC . . . bcftools-1.21/test/annotate.missing.1.out000066400000000000000000000007771467060157400204250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 20 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 30 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 40 . A T . . TSTR=new;TFLT=0.9;TINT=9 chr1 50 . A T . . . bcftools-1.21/test/annotate.missing.2.out000066400000000000000000000010161467060157400204110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=.;TINT=.;TSTR=. chr1 20 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 30 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 40 . A T . . TSTR=new;TFLT=0.9;TINT=9 chr1 50 . A T . . TSTR=.;TFLT=.;TINT=. bcftools-1.21/test/annotate.missing.3.out000066400000000000000000000010221467060157400204070ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 20 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 30 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 40 . A T . . TSTR=new;TFLT=0.9;TINT=9 chr1 50 . A T . . TSTR=.;TFLT=.;TINT=. bcftools-1.21/test/annotate.missing.4.out000066400000000000000000000007771467060157400204300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 20 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 30 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 40 . A T . . TSTR=new;TFLT=0.9;TINT=9 chr1 50 . A T . . . bcftools-1.21/test/annotate.missing.5.out000066400000000000000000000010501467060157400204120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=0.1,.;TINT=1,.;TSTR=old,. chr1 20 . A T . . TFLT=0.1,0.9;TINT=1,9;TSTR=old,new chr1 30 . A T . . TFLT=.,0.9;TINT=.,9;TSTR=.,new chr1 40 . A T . . TSTR=new;TFLT=0.9;TINT=9 chr1 50 . A T . . TSTR=.;TFLT=.;TINT=. bcftools-1.21/test/annotate.missing.6.out000066400000000000000000000010111467060157400204100ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 20 . A T . . TFLT=0.1,0.9;TINT=1,9;TSTR=old,new chr1 30 . A T . . TFLT=0.9;TINT=9;TSTR=new chr1 40 . A T . . TSTR=new;TFLT=0.9;TINT=9 chr1 50 . A T . . . bcftools-1.21/test/annotate.missing.tab000066400000000000000000000001461467060157400202130ustar00rootroot00000000000000chr1 10 A T . . . chr1 20 A T new 0.9 9 chr1 30 A T new 0.9 9 chr1 40 A T new 0.9 9 chr1 50 A T . . . bcftools-1.21/test/annotate.missing.vcf000066400000000000000000000006601467060157400202240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 10 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 20 . A T . . TFLT=0.1;TINT=1;TSTR=old chr1 30 . A T . . TFLT=.;TINT=.;TSTR=. chr1 40 . A T . . . chr1 50 . A T . . . bcftools-1.21/test/annotate.multi.1.out000066400000000000000000000004061467060157400200730ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 752566 . G A,C,T . . ANN=GT,GC,GA 1 752566 . G A,C . . 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AA=1;BB=2;X=3;Y=4 GT 0/1 0/1 1 3000001 id C . 20 PASS AA=1;BB=2;X=3;Y=4 GT 0/1 0/1 1 3000002 id C . 20 fltY;fltA;fltB;fltX BB=2;X=3;Y=4;AA=1 GT 0/1 0/1 bcftools-1.21/test/annotate8.out000066400000000000000000000014221467060157400166720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T . . FA=1.1;FR=1.1,2.2;IA=1;IR=1,2;SA=11;SR=1,222 1 2 . C T,G . . FA=1.1,9.9;FR=1.1,9.9,3.3;IA=1,2;IR=1,2,3;SA=11,99;SR=111,99,3 1 3 . C A,T . . FA=.,1.1;FR=1.1,.,2.2;IA=.,1;IR=1,.,2;SA=.,11;SR=11,.,2 bcftools-1.21/test/annotate9.out000066400000000000000000000036501467060157400167000ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 id150 C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000151 id3000151 C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 id3106154 CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 bcftools-1.21/test/annotate9.vcf000066400000000000000000000035441467060157400166510ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 id150 C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 bcftools-1.21/test/annots-mark.1.out000066400000000000000000000011241467060157400173610ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT test chr1 10611 . C G . . . GT 1/1 chr1 10623 . T C . . TAG GT 1/1 chr1 10647 . A G . . TAG GT 0/1 chr1 10671 . G C . . TAG GT 0/1 chr1 10676 . A G . . . GT 0/1 chr1 10705 . A G . . . GT 0/1 chr1 10729 . G C . . . GT 0/1 chr1 10734 . A G . . . GT 0/1 chr1 10751 . C G . . . GT 0/1 chr1 10758 . G C . . . GT 0/1 bcftools-1.21/test/annots-mark.bed000066400000000000000000000000201467060157400171370ustar00rootroot00000000000000chr1 10611 10671bcftools-1.21/test/annots-mark.vcf000066400000000000000000000007251467060157400171770ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT test chr1 10611 . C G . . . GT 1/1 chr1 10623 . T C . . . GT 1/1 chr1 10647 . A G . . . GT 0/1 chr1 10671 . G C . . . GT 0/1 chr1 10676 . A G . . . GT 0/1 chr1 10705 . A G . . . GT 0/1 chr1 10729 . G C . . . GT 0/1 chr1 10734 . A G . . . GT 0/1 chr1 10751 . C G . . . GT 0/1 chr1 10758 . G C . . . GT 0/1 bcftools-1.21/test/annots.id.2.vcf000066400000000000000000000003761467060157400170040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=GRCh38.p13 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chrM 10 rs879233578 T C . . . chrM 73 rs869183622 A C . . . chrM 73 rs869183622 A G . . . chrM 146 rs370482130 T A . . . chrM 146 rs370482130 T C . . . bcftools-1.21/test/annots.id.vcf000066400000000000000000000005621467060157400166410ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FORMAT= ##INFO= ##contig= ##reference=ref.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 50 id50 C G . . . GT 0/0 1 51 id51 C A . . . GT 0/0 1 52 id52 C T . . . GT 0/0 1 53 id53_T C T . . . GT 0/1 bcftools-1.21/test/annots.olap.tab000066400000000000000000000000631467060157400171640ustar00rootroot000000000000001 10 15 cnv10_15 1 18 19 cnv18_19 1 20 50 cnv20_50 bcftools-1.21/test/annots.vcf000066400000000000000000000051301467060157400162420ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 id1 C T 99 PASS STR=id1;AN=4;AC=0 GT:GQ 0|0:999 0|0:999 1 3000151 id2 C T 99 PASS STR=id2;AN=4;AC=0 GT:DP:GQ 0|0:99:999 0|0:99:999 1 3062915 idIndel GTTT G 99 PASS DP4=1,2,3,4;AN=4;AC=0;INDEL;STR=testIndel GT:GQ:DP:GL 0|0:999:99:-99,-9,-99 0|0:999:99:-99,-9,-99 1 3062915 idSNP G T,C 99 PASS STR=testSNP;TEST=5;DP4=1,2,3,4;AN=3;AC=0,0 GT:TT:GQ:DP:GL 0|0:9,9:999:99:-99,-9,-99,-99,-9,-99 0:9,9:999:99:-99,-9,-99 1 3106154 id4 CAAA C 99 PASS STR=id4;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 1 3106154 id5 C CT 99 PASS STR=id5;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 1 3157410 id6 GA GC,G 99 PASS STR=id6;AN=4;AC=0,0 GT:GQ:DP 0|0:99:99 0|0:99:99 1 3162006 id7 GAA GG 99 PASS STR=id7;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 1 3177144 id8 G T 99 PASS STR=id8;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 1 3177144 id9 G . 99 PASS STR=id9;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 1 3184885 id10 TAAAA TA,T 99 PASS STR=id10;AN=4;AC=0,0 GT:GQ:DP 0|0:99:99 0|0:99:99 2 3199812 id11 G GTT,GT 99 PASS STR=id11;AN=4;AC=0,0 GT:GQ:DP 0|0:999:99 0|0:999:99 3 3212016 id12 CTT C,CT 99 PASS STR=id12;AN=4;AC=0,0 GT:GQ:DP 0|0:99:99 0|0:99:99 4 3258448 id13 TACACACAC T 99 PASS STR=id13;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 bcftools-1.21/test/annots10.tab000066400000000000000000000002241467060157400163720ustar00rootroot000000000000001 3000001 . . . . . . 1 3000002 88,99 77 8.8,9.9 7.7 888,999 77 1 3000003 88,99 77 8.8,9.9 7.7 888,999 77 1 3000004 88,99 77 8.8,9.9 7.7 888,999 77 bcftools-1.21/test/annots11.tab000066400000000000000000000001141467060157400163710ustar00rootroot000000000000001 3000001 . . . 1 3000002 77 7.7 77 1 3000003 77 7.7 77 1 3000004 77 7.7 77 bcftools-1.21/test/annots11.vcf000066400000000000000000000021731467060157400164100ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000001 . C T . . . GT:AD:AF:PL:GL .:1,2:1,2:3,4:3,4 .:8,9:8,9:10,11,12:10,11,12 1 3000002 . C CT,T . . . GT:AD:AF:PL:GL 1/0:1,2,3:1,2,3:1,2,3,4,5,6:1,2,3,4,5,6 0/1:10,11,12:10,11,12:10,11,12,13,14,15:10,11,12,13,14,15 1 3000003 . C CTT . . . GT:AD:AF:PL:GL 1/0:1,2:1,2:1,2,3:1,2,3 0/1:4,5:4,5:4,5,6:4,5,6 X 3000001 . C T . . . GT:AD:AF:PL:GL .:1,2:1,2:3,4:3,4 .:8,9:8,9:10,11,12:10,11,12 X 3000002 . C CT,T . . . GT:AD:AF:PL:GL 0:1,2,3:1,2,3:1,2,3:1,2,3 0/1:10,11,12:10,11,12:10,11,12,13,14,15:10,11,12,13,14,15 X 3000003 . C CTT . . . GT:AD:AF:PL:GL 0:1,2:1,2:1,2:1,2 0/1:4,5:4,5:4,5,6:4,5,6 bcftools-1.21/test/annots12.vcf000066400000000000000000000024131467060157400164060ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A C 1 3000001 xx C T 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR:newGT 0/0:11:1.1:xxx:. 0/0:11:1.1:x:. 0/0:11:1.1:x:. 1 3000002 . C T . . . GT:newGT .:0|1 .:1|1 .:. 1 3000003 xx C T 11 q11 FLAG;IINT=.;IFLT=.;ISTR=. GT:FINT:FFLT:FSTR:newGT 0/0:.:.:.:0|1 0/0:.:.:.:1|1 0/0:.:.:.:. 1 3000004 xx C T 11 q11 FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR:newGT 0/0:11:1.1:x:0|1 0/0:11:1.1:xxx:1|1 0/0:11:1.1:xxx:. bcftools-1.21/test/annots13.tab000066400000000000000000000000741467060157400164000ustar00rootroot000000000000001 1141500 1141520 A 1 1141505 1141525 A 1 1141510 1141600 B bcftools-1.21/test/annots2.vcf000066400000000000000000000022021467060157400163210ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A 1 3000001 . C T . . . GT . . 1 3000002 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT:FINT:FFLT:FSTR 1|1:88,99:8.8,9.9:888,999 0|1:77:7.7:77 1 3000003 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT:FINT:FFLT:FSTR 1|1:88,99:8.8,9.9:888,999 0|1:77:7.7:77 1 3000004 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT:FINT:FFLT:FSTR 1|1:88,99:8.8,9.9:888,999 0|1:77:7.7:77 bcftools-1.21/test/annots28.tab000066400000000000000000000000441467060157400164030ustar00rootroot00000000000000#CHROM POS REF ALT TEST 1 1 G . 1 2 bcftools-1.21/test/annots34.tab000066400000000000000000000001321467060157400163760ustar00rootroot00000000000000chr21 8914240 8914240 8914295 chr21 8914680 8914680 8914681 chr21 8914690 8914690 8914691 bcftools-1.21/test/annots4.tab000066400000000000000000000002341467060157400163160ustar00rootroot000000000000001 1 C A,T,G 0,1.1,0 1.1,0,2.2,0 0,1,0 1,0,2,0 X,11,XXX 1,XX,222,XXX 1 2 C T,G 1.1,2.2 1.1,2.2,3.3 1,2 1,2,3 11,2 111,22,3 1 3 C T 1.1 1.1,2.2 1 1,2 11 11,2 bcftools-1.21/test/annots4.vcf000066400000000000000000000013601467060157400163270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C A,T,G . . FA=0,1.1,0;FR=1.1,0,2.2,0;IA=0,1,0;IR=1,0,2,0;SA=X,11,XXX;SR=1,XX,222,XXX 1 2 . C T,G . . FA=1.1,2.2;FR=1.1,2.2,3.3;IA=1,2;IR=1,2,3;SA=11,2;SR=111,22,3 1 3 . C T . . FA=1.1;FR=1.1,2.2;IA=1;IR=1,2;SA=11;SR=11,2 bcftools-1.21/test/annots9.tab000066400000000000000000000002061467060157400163220ustar00rootroot000000000000001 3000150 C T id3000150 1 3000151 C T id3000151 1 3062915 GTTT G id3062915_3D 1 3062915 G T,C id3062915_NP 1 3106154 CAAA C id3106154 bcftools-1.21/test/annots9.vcf000066400000000000000000000036071467060157400163420ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 id3000150 C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000151 id3000151 C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3062915 id3062915_3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 id3062915_NP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 id3106154 CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 bcftools-1.21/test/atomize.split.1.0.out000066400000000000000000000133741467060157400201010ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##contig= ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 11 101 . G C . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0 0 0 1 11 101 . G * . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 1 0 0 0 11 101 . GCGT G . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 1 0 0 0 11 101 . GCGT * . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0 1 1 1 11 102 . C T . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0 0 1 0 11 102 . C * . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 1 0 0 0 11 104 . T A . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0 1 1 0 11 104 . T * . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 1 0 0 0 11 201 . C G . . OLD_REC=11|201|CC|GG,GT|1,2 GT 0 1 1 0 11 201 . C * . . OLD_REC=11|201|CC|GG,GT|1,2 GT 0 0 0 0 11 202 . C G . . OLD_REC=11|201|CC|GG,GT|1 GT 0 1 0 0 11 202 . C * . . OLD_REC=11|201|CC|GG,GT|1 GT 0 0 1 0 11 202 . C T . . OLD_REC=11|201|CC|GG,GT|2 GT 0 0 1 0 11 202 . C * . . OLD_REC=11|201|CC|GG,GT|2 GT 0 1 0 0 12 101 rs101 G C 199 flt INDEL;AN=4;AC=4;DP=19;ISTR=SomeString;XRF=0,4;XRI=0,4;XRS=000,xx;XAF=4;XAI=444;XAS=zzz;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/0 0/0 0/0 0/1 12 101 rs101 G * 199 flt INDEL;AN=4;AC=.;DP=19;ISTR=SomeString;XRF=0,.;XRI=0,.;XRS=000,.;XAF=.;XAI=.;XAS=.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/1 1/0 0/0 0/0 12 101 rs101 GCGT G 199 flt INDEL;AN=4;AC=1;DP=19;ISTR=SomeString;XRF=0,10;XRI=0,1111;XRS=000,AAA;XAF=10;XAI=1111;XAS=AAA;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/1 1/0 0/0 0/0 12 101 rs101 GCGT * 199 flt INDEL;AN=4;AC=.;DP=19;ISTR=SomeString;XRF=0,.;XRI=0,.;XRS=000,.;XAF=.;XAI=.;XAS=.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/0 0/1 1/1 1/1 12 102 rs101 C T 199 flt INDEL;AN=4;AC=3;DP=19;ISTR=SomeString;XRF=0,300000;XRI=0,3333;XRS=000,DDD;XAF=3;XAI=33;XAS=xx;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/0 0/0 0/1 0/0 12 102 rs101 C * 199 flt INDEL;AN=4;AC=.;DP=19;ISTR=SomeString;XRF=0,.;XRI=0,.;XRS=000,.;XAF=.;XAI=.;XAS=.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/1 1/0 0/0 0/0 12 104 rs101 T A 199 flt INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=0,200;XRI=0,2222;XRS=000,BBB;XAF=200000;XAI=22;XAS=DDD;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0/0 0/1 1/1 1/0 12 104 rs101 T * 199 flt INDEL;AN=4;AC=.;DP=19;ISTR=SomeString;XRF=0,.;XRI=0,.;XRS=000,.;XAF=.;XAI=.;XAS=.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0/1 1/0 0/0 0/0 12 201 . C G . . OLD_REC=12|201|CC|GG,GT|1,2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1:1:a:0,1.1:0,1:a,b:0,1,2 1:yy:11:1.1:1.1:1:a:0,1.1:0,1:a,b:0,2 1/1:zz:22:2.2:1.1:1:a:0,1.1:0,1:a,b:0,1,2 0:.:.:.:.:.:.:.,1.1:.,.:.,.:. 12 201 . C * . . OLD_REC=12|201|CC|GG,GT|1,2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:.:.:.:0,.:0,.:a,.:0,.,. 0:yy:11:1.1:.:.:.:0,.:0,.:a,.:0,. 0/0:zz:22:2.2:.:.:.:0,.:0,.:a,.:0,.,. 0:.:.:.:.:.:.:.,1.1:.,.:.,.:. 12 202 . C G . . OLD_REC=12|201|CC|GG,GT|1 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1:1:a:0,1.1:0,1:a,b:0,1,2 1:yy:11:1.1:1.1:1:a:0,1.1:0,1:a,b:0,2 0/0:zz:22:2.2:1.1:1:a:0,1.1:0,1:a,b:0,1,2 0:.:.:.:.:.:.:.,1.1:.,.:.,.:. 12 202 . C * . . OLD_REC=12|201|CC|GG,GT|1 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:.:.:.:0,.:0,.:a,.:0,.,. 0:yy:11:1.1:.:.:.:0,.:0,.:a,.:0,. 1/1:zz:22:2.2:.:.:.:0,.:0,.:a,.:0,.,. 0:.:.:.:.:.:.:.,1.1:.,.:.,.:. 12 202 . C T . . OLD_REC=12|201|CC|GG,GT|2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:yy:11:1.1:2.2:2:b:0,2.2:0,2:a,c:0,5 1/1:zz:22:2.2:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:.:.:.:.:.:.:.,2.2:.,.:.,.:. 12 202 . C * . . OLD_REC=12|201|CC|GG,GT|2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:.:.:.:0,.:0,.:a,.:0,.,. 1:yy:11:1.1:.:.:.:0,.:0,.:a,.:0,. 0/0:zz:22:2.2:.:.:.:0,.:0,.:a,.:0,.,. 0:.:.:.:.:.:.:.,2.2:.,.:.,.:. bcftools-1.21/test/atomize.split.1.1.out000066400000000000000000000110441467060157400200720ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##contig= ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 11 101 . GCGT G . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 1 0 0 0 11 101 . G C . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0 0 0 1 11 102 . C T . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0 0 1 0 11 104 . T A . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2 GT 0 1 0 0 11 104 . T A . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0 0 1 0 11 201 . C G . . OLD_REC=11|201|CC|GG,GT|1 GT 0 1 0 0 11 201 . C G . . OLD_REC=11|201|CC|GG,GT|2 GT 0 0 1 0 11 202 . C G . . OLD_REC=11|201|CC|GG,GT|1 GT 0 1 0 0 11 202 . C T . . OLD_REC=11|201|CC|GG,GT|2 GT 0 0 1 0 12 101 rs101 GCGT G 199 flt INDEL;AN=4;AC=1;DP=19;ISTR=SomeString;XRF=0,10;XRI=0,1111;XRS=000,AAA;XAF=10;XAI=1111;XAS=AAA;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/1 1/0 0/0 0/0 12 101 rs101 G C 199 flt INDEL;AN=4;AC=4;DP=19;ISTR=SomeString;XRF=0,4;XRI=0,4;XRS=000,xx;XAF=4;XAI=444;XAS=zzz;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/0 0/0 0/0 0/1 12 102 rs101 C T 199 flt INDEL;AN=4;AC=3;DP=19;ISTR=SomeString;XRF=0,300000;XRI=0,3333;XRS=000,DDD;XAF=3;XAI=33;XAS=xx;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/0 0/0 0/1 0/0 12 104 rs101 T A 199 flt INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=0,200;XRI=0,2222;XRS=000,BBB;XAF=200000;XAI=22;XAS=DDD;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|2 GT 0/0 0/1 1/0 1/0 12 104 rs101 T A 199 flt INDEL;AN=4;AC=3;DP=19;ISTR=SomeString;XRF=0,300000;XRI=0,3333;XRS=000,DDD;XAF=3;XAI=33;XAS=xx;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/0 0/0 0/1 0/0 12 201 . C G . . OLD_REC=12|201|CC|GG,GT|1 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1:1:a:0,1.1:0,1:a,b:0,1,2 1:yy:11:1.1:1.1:1:a:0,1.1:0,1:a,b:0,2 0/0:zz:22:2.2:1.1:1:a:0,1.1:0,1:a,b:0,1,2 0:.:.:.:2.2:.:.:.,1.1:.,.:.,.:. 12 201 . C G . . OLD_REC=12|201|CC|GG,GT|2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:yy:11:1.1:2.2:2:b:0,2.2:0,2:a,c:0,5 1/1:zz:22:2.2:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:.:.:.:2.2:.:.:.,1.1:.,.:.,.:. 12 202 . C G . . OLD_REC=12|201|CC|GG,GT|1 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1:1:a:0,1.1:0,1:a,b:0,1,2 1:yy:11:1.1:1.1:1:a:0,1.1:0,1:a,b:0,2 0/0:zz:22:2.2:1.1:1:a:0,1.1:0,1:a,b:0,1,2 0:.:.:.:2.2:.:.:.,1.1:.,.:.,.:. 12 202 . C T . . OLD_REC=12|201|CC|GG,GT|2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:yy:11:1.1:2.2:2:b:0,2.2:0,2:a,c:0,5 1/1:zz:22:2.2:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:.:.:.:2.2:.:.:.,1.1:.,.:.,.:. bcftools-1.21/test/atomize.split.1.2.out000066400000000000000000000077751467060157400201130ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##contig= ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 11 101 . G C . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT . 0 0 1 11 101 . GCGT G . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 1 . . . 11 102 . C T . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT . 0 1 0 11 104 . T A . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT . 1 1 0 11 201 . C G . . OLD_REC=11|201|CC|GG,GT|1,2 GT 0 1 1 0 11 202 . C G . . OLD_REC=11|201|CC|GG,GT|1 GT 0 1 . 0 11 202 . C T . . OLD_REC=11|201|CC|GG,GT|2 GT 0 . 1 0 12 101 rs101 G C 199 flt INDEL;AN=4;AC=4;DP=19;ISTR=SomeString;XRF=0,4;XRI=0,4;XRS=000,xx;XAF=4;XAI=444;XAS=zzz;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/. ./0 0/0 0/1 12 101 rs101 GCGT G 199 flt INDEL;AN=4;AC=1;DP=19;ISTR=SomeString;XRF=0,10;XRI=0,1111;XRS=000,AAA;XAF=10;XAI=1111;XAS=AAA;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/1 1/. ./. ./. 12 102 rs101 C T 199 flt INDEL;AN=4;AC=3;DP=19;ISTR=SomeString;XRF=0,300000;XRI=0,3333;XRS=000,DDD;XAF=3;XAI=33;XAS=xx;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/. ./0 0/1 0/0 12 104 rs101 T A 199 flt INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=0,200;XRI=0,2222;XRS=000,BBB;XAF=200000;XAI=22;XAS=DDD;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0/. ./1 1/1 1/0 12 201 . C G . . OLD_REC=12|201|CC|GG,GT|1,2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1:1:a:0,1.1:0,1:a,b:0,1,2 1:yy:11:1.1:1.1:1:a:0,1.1:0,1:a,b:0,2 1/1:zz:22:2.2:1.1:1:a:0,1.1:0,1:a,b:0,1,2 0:.:.:.:.:.:.:.:.:.,.:. 12 202 . C G . . OLD_REC=12|201|CC|GG,GT|1 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1:1:a:0,1.1:0,1:a,b:0,1,2 1:yy:11:1.1:1.1:1:a:0,1.1:0,1:a,b:0,2 ./.:zz:22:2.2:1.1:1:a:0,1.1:0,1:a,b:0,1,2 0:.:.:.:.:.:.:.:.:.,.:. 12 202 . C T . . OLD_REC=12|201|CC|GG,GT|2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:2.2:2:b:0,2.2:0,2:a,c:0,3,5 .:yy:11:1.1:2.2:2:b:0,2.2:0,2:a,c:0,5 1/1:zz:22:2.2:2.2:2:b:0,2.2:0,2:a,c:0,3,5 0:.:.:.:.:.:.:.:.:.,.:. bcftools-1.21/test/atomize.split.1.3.out000066400000000000000000000103771467060157400201040ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##contig= ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 11 101 . G C,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 2 0 0 1 11 101 . GCGT G,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 1 2 2 2 11 102 . C T,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 2 0 1 0 11 104 . T A,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 2 1 1 0 11 201 . C G,* . . OLD_REC=11|201|CC|GG,GT|1,2 GT 0 1 1 0 11 202 . C G,* . . OLD_REC=11|201|CC|GG,GT|1 GT 0 1 2 0 11 202 . C T,* . . OLD_REC=11|201|CC|GG,GT|2 GT 0 2 1 0 12 101 rs101 G C,* 199 flt INDEL;AN=4;AC=4,.;DP=19;ISTR=SomeString;XRF=0,4,.;XRI=0,4,.;XRS=000,xx,.;XAF=4,.;XAI=444,.;XAS=zzz,.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/2 2/0 0/0 0/1 12 101 rs101 GCGT G,* 199 flt INDEL;AN=4;AC=1,.;DP=19;ISTR=SomeString;XRF=0,10,.;XRI=0,1111,.;XRS=000,AAA,.;XAF=10,.;XAI=1111,.;XAS=AAA,.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/1 1/2 2/2 2/2 12 102 rs101 C T,* 199 flt INDEL;AN=4;AC=3,.;DP=19;ISTR=SomeString;XRF=0,300000,.;XRI=0,3333,.;XRS=000,DDD,.;XAF=3,.;XAI=33,.;XAS=xx,.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/2 2/0 0/1 0/0 12 104 rs101 T A,* 199 flt INDEL;AN=4;AC=2,.;DP=19;ISTR=SomeString;XRF=0,200,.;XRI=0,2222,.;XRS=000,BBB,.;XAF=200000,.;XAI=22,.;XAS=DDD,.;OLD_REC=12|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0/2 2/1 1/1 1/0 12 201 . C G,* . . OLD_REC=12|201|CC|GG,GT|1,2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1,.:1,.:a,.:0,1.1,.:0,1,.:a,b,.:0,1,2,.,.,. 1:yy:11:1.1:1.1,.:1,.:a,.:0,1.1,.:0,1,.:a,b,.:0,2,. 1/1:zz:22:2.2:1.1,.:1,.:a,.:0,1.1,.:0,1,.:a,b,.:0,1,2,.,.,. 0:.:.:.:.,.:.,.:.,.:.:.:.,.,.:. 12 202 . C G,* . . OLD_REC=12|201|CC|GG,GT|1 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:1.1,.:1,.:a,.:0,1.1,.:0,1,.:a,b,.:0,1,2,.,.,. 1:yy:11:1.1:1.1,.:1,.:a,.:0,1.1,.:0,1,.:a,b,.:0,2,. 2/2:zz:22:2.2:1.1,.:1,.:a,.:0,1.1,.:0,1,.:a,b,.:0,1,2,.,.,. 0:.:.:.:.,.:.,.:.,.:.:.:.,.,.:. 12 202 . C T,* . . OLD_REC=12|201|CC|GG,GT|2 GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:0:0:2.2,.:2,.:b,.:0,2.2,.:0,2,.:a,c,.:0,3,5,.,.,. 2:yy:11:1.1:2.2,.:2,.:b,.:0,2.2,.:0,2,.:a,c,.:0,5,. 1/1:zz:22:2.2:2.2,.:2,.:b,.:0,2.2,.:0,2,.:a,c,.:0,3,5,.,.,. 0:.:.:.:.,.:.,.:.,.:.:.:.,.,.:. bcftools-1.21/test/atomize.split.1.vcf000066400000000000000000000053201467060157400177020ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##contig= ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 11 101 . GCGT G,GCGA,GTGA,CCGT . . . GT 1 2 3 4 11 201 . CC GG,GT . . . GT 0 1 2 0 12 101 rs101 GCGT G,GCGA,GTGA,CCGT 199 flt INDEL;AN=4;AC=1,2,3,4;DP=19;ISTR=SomeString;XRF=0,1e+01,2e+02,300000,4;XRI=0,1111,2222,3333,4;XRS=000,AAA,BBB,DDD,xx;XAF=1e+01,200000,3,4.0;XAI=1111,22,33,444;XAS=AAA,DDD,xx,zzz;XGF=1e+01,2e+02,3e+03,500000,.,9e+09,7;XGI=1111,2222,3333,5555,.,9999,7;XGS=A,B,C,E,.,F,x GT 0/1 1/2 2/3 2/4 12 201 . CC GG,GT . . . GT:FSTR:FFI:FFF:FAF:FAI:FAS:FRF:FRI:FRS:PL 0/0:xx:00:0.0:1.1,2.2:1,2:a,b:0.0,1.1,2.2:0,1,2:a,b,c:0,1,2,3,4,5 1:yy:11:1.1:1.1,2.2:1,2:a,b:0.0,1.1,2.2:0,1,2:a,b,c:0,2,5 2/2:zz:22:2.2:1.1,2.2:1,2:a,b:0.0,1.1,2.2:0,1,2:a,b,c:0,1,2,3,4,5 0 bcftools-1.21/test/atomize.split.2.1.out000066400000000000000000000016621467060157400201000ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 50 . A . . . . . . 1 100 . C G . . OLD_REC=1|100|CC|GG|1 GT 0/1 1 101 . C G . . OLD_REC=1|100|CC|GG|1 GT 0/1 1 110 . C T,<*> . . . GT 0/1 1 200 . A C . . AD=1,3;QS=10,30;OLD_REC=1|200|AAA|AAC,CAC|2 GT:AD:QS 0/1:1,3:10,30 1 202 . A C,* . . AD=1,5,.;QS=10,50,.;OLD_REC=1|200|AAA|AAC,CAC|1,2 GT:AD:QS 1/1:1,5,.:10,50,. 1 300 . A . . . . . . bcftools-1.21/test/atomize.split.2.2.out000066400000000000000000000016501467060157400200760ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 50 . A . . . . . . 1 100 . C G . . OLD_REC=1|100|CC|GG|1 GT 0/1 1 101 . C G . . OLD_REC=1|100|CC|GG|1 GT 0/1 1 110 . C T,<*> . . . GT 0/1 1 200 . A C . . AD=1,3;QS=10,30;OLD_REC=1|200|AAA|AAC,CAC|2 GT:AD:QS 0/1:1,3:10,30 1 202 . A C . . AD=1,5;QS=10,50;OLD_REC=1|200|AAA|AAC,CAC|1,2 GT:AD:QS 1/1:1,5:10,50 1 300 . A . . . . . . bcftools-1.21/test/atomize.split.2.vcf000066400000000000000000000011501467060157400177000ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 50 . A . . . . . . 1 100 . CC GG . . . GT 0/1 1 110 . C T,<*> . . . GT 0/1 1 200 . AAA AAC,CAC . . AD=1,2,3;QS=10,20,30 GT:AD:QS 1/2:1,2,3:10,20,30 1 300 . A . . . . . . bcftools-1.21/test/atomize.split.3.1.out000066400000000000000000000004141467060157400200730ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 50 . G C . . . GT .|1 1 50 . G T . . . GT 1|. bcftools-1.21/test/atomize.split.3.vcf000066400000000000000000000003021467060157400176770ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 50 . G C,T . . . GT 2|1 bcftools-1.21/test/atomize.split.4.1.out000066400000000000000000000010451467060157400200750ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 11 100 . C G . . OLD_REC=11|100|CC|GG|1 11 101 . C G . . OLD_REC=11|100|CC|GG|1 11 200 . C G . . OLD_REC=11|200|CC|GGGG|1 11 201 . C CGG . . OLD_REC=11|200|CC|GGGG|1 11 201 . C G . . OLD_REC=11|200|CC|GGGG|1 11 300 . C CGGG . . OLD_REC=11|300|C|GGGG|1 11 300 . C G . . OLD_REC=11|300|C|GGGG|1 bcftools-1.21/test/atomize.split.4.2.out000066400000000000000000000005751467060157400201050ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 11 100 . C G . . OLD_REC=11|100|CC|GG|1 11 101 . C G . . OLD_REC=11|100|CC|GG|1 11 200 . CC GGGG . . . 11 300 . C GGGG . . . bcftools-1.21/test/atomize.split.4.vcf000066400000000000000000000002401467060157400177010ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 11 100 . CC GG . . . 11 200 . CC GGGG . . . 11 300 . C GGGG . . . bcftools-1.21/test/atomize.split.5.1.out000066400000000000000000000016301467060157400200760ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##contig= ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 105174100 . G C . . OLD_REC=1|105174100|GCCCGC|CGCCCCGC|1 GT 0/1 1 105174100 . G GGC . . OLD_REC=1|105174100|GCCCGC|CGCCCCGC|1 GT 0/1 2 36744887 . C G . . OLD_REC=2|36744886|GCCCC|GGCT|1 GT 0/1 2 36744889 . C T . . OLD_REC=2|36744886|GCCCC|GGCT|1 GT 0/1 2 36744889 . CC C . . OLD_REC=2|36744886|GCCCC|GGCT|1 GT 0/1 11 101 . G C . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/. 11 101 . GCGT G . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/1 11 102 . C T . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/. 11 104 . T A . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0/. bcftools-1.21/test/atomize.split.5.2.out000066400000000000000000000016501467060157400201010ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##contig= ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 105174100 . G C,* . . OLD_REC=1|105174100|GCCCGC|CGCCCCGC|1 GT 0/1 1 105174100 . G GGC,* . . OLD_REC=1|105174100|GCCCGC|CGCCCCGC|1 GT 0/1 2 36744887 . C G . . OLD_REC=2|36744886|GCCCC|GGCT|1 GT 0/1 2 36744889 . C T,* . . OLD_REC=2|36744886|GCCCC|GGCT|1 GT 0/1 2 36744889 . CC C,* . . OLD_REC=2|36744886|GCCCC|GGCT|1 GT 0/1 11 101 . G C,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|4 GT 0/2 11 101 . GCGT G,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|1 GT 0/1 11 102 . C T,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|3 GT 0/2 11 104 . T A,* . . OLD_REC=11|101|GCGT|G,GCGA,GTGA,CCGT|2,3 GT 0/2 bcftools-1.21/test/atomize.split.5.vcf000066400000000000000000000004641467060157400177120ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 105174100 . GCCCGC CGCCCCGC . . . GT 0/1 2 36744886 . GCCCC GGCT . . . GT 0/1 11 101 . GCGT G,GCGA,GTGA,CCGT . . . GT 0/1 bcftools-1.21/test/call-G.1.out000066400000000000000000000052451467060157400162360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=test.fna ##contig= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 smpl3 smpl4 smpl5 smpl6 smpl7 smpl8 smpl9 smpl10 smpl11 smpl12 smpl13 smpl14 smpl15 smpl16 smpl17 smpl18 smpl19 smpl20 smpl21 smpl22 smpl23 smpl24 smpl25 smpl26 culprit smpl28 smpl29 smpl30 smpl31 smpl32 smpl33 1 378 . G A,T 461.915 . DP=1418;AN_POP=1000;AC_POP=500,0,0;AC=5,5;AN=48;DP4=675,356,36,17;MQ=57 GT:PL:AD:QS 0/0:0,3,60,3,60,60:1,0,0:60,0,0 0/0:0,33,255,33,255,255:11,0,0:425,0,0 0/2:98,119,255,0,173,155:7,0,6:224,0,175 0/0:0,12,155,12,155,155:4,0,0:174,0,0 0/0:0,24,244,24,244,244:8,0,0:324,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 0/2:37,37,37,3,3,0:0,0,1:0,0,37 0/0:0,15,161,15,161,161:5,0,0:187,0,0 0/0:0,15,192,15,192,192:5,0,0:219,0,0 0/0:0,6,94,6,94,94:2,0,0:101,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 0/0:0,27,255,27,255,255:9,0,0:399,0,0 0/1:31,0,19,34,22,53:1,1,0:25,37,0 0/0:0,18,165,18,165,165:6,0,0:222,0,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 0/1:49,3,0,49,3,49:0,1,0:0,49,0 ./.:0,0,0,0,0,0:0,0,0:0,0,0 0/0:0,3,41,3,41,41:1,0,0:41,0,0 0/0:0,39,255,39,255,255:13,0,0:502,0,0 0/0:11,0,227,38,230,255:9,1,0:399,41,0 0/0:0,3,41,3,41,41:1,0,0:41,0,0 1/2:218,98,86,135,0,126:0,4,3:0,160,112 0/0:0,21,205,21,205,205:7,0,0:250,0,0 0/0:0,18,200,18,200,200:6,0,0:261,0,0 0/2:82,91,200,0,119,113:3,0,2:133,0,97 0/0:0,9,137,9,137,137:3,0,0:161,0,0 0/1:73,38,35,73,38,73:0,1,0:0,41,0 1/2:107,19,47,57,0,88:1,3,1:41,123,60 bcftools-1.21/test/call-G.2.1.out000066400000000000000000000070661467060157400164010ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07000 NA07056 NA12046 NA12144 NA12156 NA12234 NA12249 NA12282 NA12283 NA12286 NA12340 NA12341 NA12342 NA12399 NA12414 NA12546 NA12717 NA12718 NA12748 NA12749 NA12750 NA12776 NA12828 NA12843 NA18502 NA18867 NA18908 NA18933 NA18934 NA19108 NA19117 NA19119 NA19129 NA19131 NA19138 NA19147 NA19149 NA19159 NA19185 NA19189 NA19197 NA19198 NA19206 NA19213 NA19214 NA19223 NA19235 NA19236 NA19238 NA19239 NA19248 NA19256 15 201 . A G 858.4 . DP=80;AN_POP=1000;AC_POP=1000,0;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0;AC=79;AN=104;DP4=19,17,21,15;MQ=59 GT:PL:AD 0/1:0,3,36:1,0 0/1:0,6,93:2,0 0/1:0,3,33:1,0 0/1:0,3,32:1,0 0/1:0,3,36:1,0 0/1:0,3,32:1,0 0/1:0,3,40:1,0 0/1:0,6,79:2,0 0/1:0,3,42:1,0 0/1:0,6,64:2,0 0/1:0,6,67:2,0 0/1:0,6,66:2,0 0/1:0,9,96:3,0 0/1:0,3,32:1,0 0/1:0,3,36:1,0 0/1:0,3,31:1,0 0/1:0,3,44:1,0 0/1:0,3,44:1,0 0/1:0,6,61:2,0 0/1:0,3,60:1,0 0/1:0,6,60:2,0 0/1:0,6,57:2,0 0/1:0,3,31:1,0 0/1:0,6,68:2,0 0/1:0,3,60:1,0 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:37,3,0:0,1 1/1:60,3,0:0,1 1/1:38,3,0:0,1 1/1:36,3,0:0,1 1/1:37,3,0:0,1 1/1:85,9,0:0,3 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:63,6,0:0,2 1/1:29,3,0:0,1 1/1:32,3,0:0,1 1/1:43,3,0:0,1 1/1:27,3,0:0,1 1/1:43,3,0:0,1 1/1:34,3,0:0,1 1/1:46,3,0:0,1 1/1:144,12,0:0,4 1/1:59,3,0:0,1 1/1:16,3,0:0,1 1/1:37,3,0:0,1 1/1:57,6,0:0,2 1/1:91,6,0:0,2 1/1:21,3,0:0,1 1/1:52,6,0:0,2 1/1:26,3,0:0,1 bcftools-1.21/test/call-G.2.out000066400000000000000000000062761467060157400162440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=test.fna ##contig= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 smpl3 smpl4 smpl5 smpl6 smpl7 smpl8 smpl9 smpl10 smpl11 smpl12 smpl13 smpl14 smpl15 smpl16 smpl17 smpl18 smpl19 smpl20 smpl21 smpl22 smpl23 smpl24 smpl25 smpl26 culprit smpl28 smpl29 smpl30 smpl31 smpl32 smpl33 1 378 . G A,T,C 169.281 . DP=1418;AN_POP=1000;AC_POP=500,0,0;AC=6,5,1;AN=48;DP4=675,356,36,17;MQ=57 GT:PL:AD:QS 0/0:0,3,60,3,60,60,3,60,60,60:1,0,0,0:60,0,0,0 0/0:0,33,255,33,255,255,33,255,255,255:11,0,0,0:425,0,0,0 0/2:98,119,255,0,173,155,119,255,173,255:7,0,6,0:224,0,175,0 0/0:0,12,155,12,155,155,12,155,155,155:4,0,0,0:174,0,0,0 0/0:0,24,244,24,244,244,24,244,244,244:8,0,0,0:324,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 2/2:37,37,37,3,3,0,37,37,3,37:0,0,1,0:0,0,37,0 0/0:0,15,161,15,161,161,15,161,161,161:5,0,0,0:187,0,0,0 0/0:0,15,192,15,192,192,15,192,192,192:5,0,0,0:219,0,0,0 0/0:0,6,94,6,94,94,6,94,94,94:2,0,0,0:101,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0/0:0,27,255,27,255,255,27,255,255,255:9,0,0,0:399,0,0,0 0/1:31,0,19,34,22,53,34,22,53,53:1,1,0,0:25,37,0,0 0/0:0,18,165,18,165,165,18,165,165,165:6,0,0,0:222,0,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 1/1:49,3,0,49,3,49,49,3,49,49:0,1,0,0:0,49,0,0 ./.:0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0/0:0,3,41,3,41,41,3,41,41,41:1,0,0,0:41,0,0,0 0/0:0,39,255,39,255,255,39,255,255,255:13,0,0,0:502,0,0,0 0/0:11,0,227,38,230,255,38,230,255,255:9,1,0,0:399,41,0,0 0/0:0,3,41,3,41,41,3,41,41,41:1,0,0,0:41,0,0,0 1/2:218,98,86,135,0,126,218,98,135,218:0,4,3,0:0,160,112,0 0/0:0,21,205,21,205,205,21,205,205,205:7,0,0,0:250,0,0,0 0/0:0,18,200,18,200,200,18,200,200,200:6,0,0,0:261,0,0,0 0/2:82,91,200,0,119,113,91,200,119,200:3,0,2,0:133,0,97,0 0/0:0,9,137,9,137,137,9,137,137,137:3,0,0,0:161,0,0,0 1/3:73,38,35,73,38,73,38,0,38,35:0,1,0,1:0,41,0,41 0/1:107,19,47,57,0,88,110,56,91,141:1,3,1,0:41,123,60,0 bcftools-1.21/test/call-G.2.vcf000066400000000000000000000072151467060157400162050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07000 NA07056 NA12046 NA12144 NA12156 NA12234 NA12249 NA12282 NA12283 NA12286 NA12340 NA12341 NA12342 NA12399 NA12414 NA12546 NA12717 NA12718 NA12748 NA12749 NA12750 NA12776 NA12828 NA12843 NA18502 NA18867 NA18908 NA18933 NA18934 NA19108 NA19117 NA19119 NA19129 NA19131 NA19138 NA19147 NA19149 NA19159 NA19185 NA19189 NA19197 NA19198 NA19206 NA19213 NA19214 NA19223 NA19235 NA19236 NA19238 NA19239 NA19248 NA19256 15 201 . A G,<*> 0 . DP=80;AN_POP=1000;AC_POP=1000,0;I16=19,17,21,15,1380,57328,1308,52148,2160,129600,2137,127369,613,12599,514,10028;QS=25,27,0;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0 PL:AD 0,3,36,3,36,36:1,0,0 0,6,93,6,93,93:2,0,0 0,3,33,3,33,33:1,0,0 0,3,32,3,32,32:1,0,0 0,3,36,3,36,36:1,0,0 0,3,32,3,32,32:1,0,0 0,3,40,3,40,40:1,0,0 0,6,79,6,79,79:2,0,0 0,3,42,3,42,42:1,0,0 0,6,64,6,64,64:2,0,0 0,6,67,6,67,67:2,0,0 0,6,66,6,66,66:2,0,0 0,9,96,9,96,96:3,0,0 0,3,32,3,32,32:1,0,0 0,3,36,3,36,36:1,0,0 0,3,31,3,31,31:1,0,0 0,3,44,3,44,44:1,0,0 0,3,44,3,44,44:1,0,0 0,6,61,6,61,61:2,0,0 0,3,60,3,60,60:1,0,0 0,6,60,6,60,60:2,0,0 0,6,57,6,57,57:2,0,0 0,3,31,3,31,31:1,0,0 0,6,68,6,68,68:2,0,0 0,3,60,3,60,60:1,0,0 39,3,0,39,3,39:0,1,0 31,3,0,31,3,31:0,1,0 37,3,0,37,3,37:0,1,0 60,3,0,60,3,60:0,1,0 38,3,0,38,3,38:0,1,0 36,3,0,36,3,36:0,1,0 37,3,0,37,3,37:0,1,0 85,9,0,85,9,85:0,3,0 39,3,0,39,3,39:0,1,0 31,3,0,31,3,31:0,1,0 63,6,0,63,6,63:0,2,0 29,3,0,29,3,29:0,1,0 32,3,0,32,3,32:0,1,0 43,3,0,43,3,43:0,1,0 27,3,0,27,3,27:0,1,0 43,3,0,43,3,43:0,1,0 34,3,0,34,3,34:0,1,0 46,3,0,46,3,46:0,1,0 144,12,0,144,12,144:0,4,0 59,3,0,59,3,59:0,1,0 16,3,0,16,3,16:0,1,0 37,3,0,37,3,37:0,1,0 57,6,0,57,6,57:0,2,0 91,6,0,91,6,91:0,2,0 21,3,0,21,3,21:0,1,0 52,6,0,52,6,52:0,2,0 26,3,0,26,3,26:0,1,0 bcftools-1.21/test/call-G.vcf000066400000000000000000000054761467060157400160540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=test.fna ##contig= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 smpl3 smpl4 smpl5 smpl6 smpl7 smpl8 smpl9 smpl10 smpl11 smpl12 smpl13 smpl14 smpl15 smpl16 smpl17 smpl18 smpl19 smpl20 smpl21 smpl22 smpl23 smpl24 smpl25 smpl26 culprit smpl28 smpl29 smpl30 smpl31 smpl32 smpl33 1 378 . G A,T,C 0 . DP=1418;AN_POP=1000;AC_POP=500,0,0;I16=675,356,36,17,49274,2.62616e+06,2313,113051,58808,3.52801e+06,3000,180000,21513,499753,1170,27336;QS=247.89,7.1438,4.46622,0.5 PL:AD:QS 0,3,60,3,60,60,3,60,60,60:1,0,0,0:60,0,0,0 0,33,255,33,255,255,33,255,255,255:11,0,0,0:425,0,0,0 98,119,255,0,173,155,119,255,173,255:7,0,6,0:224,0,175,0 0,12,155,12,155,155,12,155,155,155:4,0,0,0:174,0,0,0 0,24,244,24,244,244,24,244,244,244:8,0,0,0:324,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 37,37,37,3,3,0,37,37,3,37:0,0,1,0:0,0,37,0 0,15,161,15,161,161,15,161,161,161:5,0,0,0:187,0,0,0 0,15,192,15,192,192,15,192,192,192:5,0,0,0:219,0,0,0 0,6,94,6,94,94,6,94,94,94:2,0,0,0:101,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,27,255,27,255,255,27,255,255,255:9,0,0,0:399,0,0,0 31,0,19,34,22,53,34,22,53,53:1,1,0,0:25,37,0,0 0,18,165,18,165,165,18,165,165,165:6,0,0,0:222,0,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 49,3,0,49,3,49,49,3,49,49:0,1,0,0:0,49,0,0 0,0,0,0,0,0,0,0,0,0:0,0,0,0:0,0,0,0 0,3,41,3,41,41,3,41,41,41:1,0,0,0:41,0,0,0 0,39,255,39,255,255,39,255,255,255:13,0,0,0:502,0,0,0 11,0,227,38,230,255,38,230,255,255:9,1,0,0:399,41,0,0 0,3,41,3,41,41,3,41,41,41:1,0,0,0:41,0,0,0 218,98,86,135,0,126,218,98,135,218:0,4,3,0:0,160,112,0 0,21,205,21,205,205,21,205,205,205:7,0,0,0:250,0,0,0 0,18,200,18,200,200,18,200,200,200:6,0,0,0:261,0,0,0 82,91,200,0,119,113,91,200,119,200:3,0,2,0:133,0,97,0 0,9,137,9,137,137,9,137,137,137:3,0,0,0:161,0,0,0 73,38,35,73,38,73,38,0,38,35:0,1,0,1:0,41,0,41 107,19,47,57,0,88,110,56,91,141:1,3,1,0:41,123,60,0 bcftools-1.21/test/call.af-fixation.1.out000066400000000000000000000030651467060157400202540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07051_CEU NA12843_CEU NA18488_YRI NA18489_YRI NA18498_YRI NA18504_YRI NA18510_YRI NA18519_YRI NA18858_YRI NA18861_YRI NA18868_YRI NA18871_YRI NA18874_YRI NA18881_YRI NA18907_YRI NA18909_YRI NA18917_YRI NA18933_YRI NA18934_YRI NA19108_YRI NA19119_YRI NA19129_YRI NA19131_YRI NA19138_YRI NA19147_YRI NA19189_YRI NA19197_YRI NA19198_YRI NA19206_YRI NA19214_YRI NA19223_YRI NA19238_YRI NA19239_YRI NA19248_YRI NA19256_YRI 2 136608646 . G . 24.5121 . AN=70;DP4=95,24,45,11;MQ=59 GT:AD 0/0:0 0/0:1 0/0:2 0/0:1 0/0:2 0/0:2 0/0:2 0/0:1 0/0:7 0/0:8 0/0:2 0/0:1 0/0:2 0/0:6 0/0:7 0/0:4 0/0:7 0/0:3 0/0:2 0/0:5 0/0:1 0/0:4 0/0:1 0/0:4 0/0:2 0/0:6 0/0:1 0/0:2 0/0:1 0/0:1 0/0:1 0/0:4 0/0:2 0/0:1 0/0:2 bcftools-1.21/test/call.af-fixation.2.out000066400000000000000000000036171467060157400202600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07051_CEU NA12843_CEU NA18488_YRI NA18489_YRI NA18498_YRI NA18504_YRI NA18510_YRI NA18519_YRI NA18858_YRI NA18861_YRI NA18868_YRI NA18871_YRI NA18874_YRI NA18881_YRI NA18907_YRI NA18909_YRI NA18917_YRI NA18933_YRI NA18934_YRI NA19108_YRI NA19119_YRI NA19129_YRI NA19131_YRI NA19138_YRI NA19147_YRI NA19189_YRI NA19197_YRI NA19198_YRI NA19206_YRI NA19214_YRI NA19223_YRI NA19238_YRI NA19239_YRI NA19248_YRI NA19256_YRI 2 136608646 . G A 4.92443 . AC=2;AN=70;DP4=95,24,45,11;MQ=59 GT:PL:AD 0/1:32,3,0:0,1 0/1:0,3,37:1,0 0/0:0,6,77:2,0 0/0:0,3,33:1,0 0/0:0,6,67:2,0 0/0:0,6,67:2,0 0/0:0,6,67:2,0 0/0:0,3,60:1,0 0/0:0,21,147:7,0 0/0:0,24,161:8,0 0/0:0,6,52:2,0 0/0:0,3,38:1,0 0/0:0,6,72:2,0 0/0:0,18,197:6,0 0/0:0,21,175:7,0 0/0:0,12,129:4,0 0/0:0,21,220:7,0 0/0:0,9,111:3,0 0/0:0,6,76:2,0 0/0:0,15,125:5,0 0/0:0,3,32:1,0 0/0:0,12,110:4,0 0/0:0,3,41:1,0 0/0:0,12,124:4,0 0/0:0,6,70:2,0 0/0:0,18,140:6,0 0/0:0,3,22:1,0 0/0:0,6,63:2,0 0/0:0,3,46:1,0 0/0:0,3,39:1,0 0/0:0,3,42:1,0 0/0:0,12,142:4,0 0/0:0,6,67:2,0 0/0:0,3,39:1,0 0/0:0,6,54:2,0 bcftools-1.21/test/call.af-fixation.3.out000066400000000000000000000047311467060157400202570ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07051_CEU NA12843_CEU NA18488_YRI NA18489_YRI NA18498_YRI NA18504_YRI NA18510_YRI NA18519_YRI NA18858_YRI NA18861_YRI NA18868_YRI NA18871_YRI NA18874_YRI NA18881_YRI NA18907_YRI NA18909_YRI NA18917_YRI NA18933_YRI NA18934_YRI NA19108_YRI NA19119_YRI NA19129_YRI NA19131_YRI NA19138_YRI NA19147_YRI NA19189_YRI NA19197_YRI NA19198_YRI NA19206_YRI NA19214_YRI NA19223_YRI NA19238_YRI NA19239_YRI NA19248_YRI NA19256_YRI 2 136608646 . G A 4.92443 . AC=2;AN=70;DP4=95,24,45,11;MQ=59 GT:PL:AD:GP:GQ 0/1:32,3,0:0,1:0.000315005,0.500435,0.49925:3 0/1:0,3,37:1,0:0.499357,0.500543,9.96349e-05:3 0/0:0,6,77:2,0:1,0,0:127 0/0:0,3,33:1,0:1,0,0:127 0/0:0,6,67:2,0:1,0,0:127 0/0:0,6,67:2,0:1,0,0:127 0/0:0,6,67:2,0:1,0,0:127 0/0:0,3,60:1,0:1,0,0:127 0/0:0,21,147:7,0:1,0,0:127 0/0:0,24,161:8,0:1,0,0:127 0/0:0,6,52:2,0:1,0,0:127 0/0:0,3,38:1,0:1,0,0:127 0/0:0,6,72:2,0:1,0,0:127 0/0:0,18,197:6,0:1,0,0:127 0/0:0,21,175:7,0:1,0,0:127 0/0:0,12,129:4,0:1,0,0:127 0/0:0,21,220:7,0:1,0,0:127 0/0:0,9,111:3,0:1,0,0:127 0/0:0,6,76:2,0:1,0,0:127 0/0:0,15,125:5,0:1,0,0:127 0/0:0,3,32:1,0:1,0,0:127 0/0:0,12,110:4,0:1,0,0:127 0/0:0,3,41:1,0:1,0,0:127 0/0:0,12,124:4,0:1,0,0:127 0/0:0,6,70:2,0:1,0,0:127 0/0:0,18,140:6,0:1,0,0:127 0/0:0,3,22:1,0:1,0,0:127 0/0:0,6,63:2,0:1,0,0:127 0/0:0,3,46:1,0:1,0,0:127 0/0:0,3,39:1,0:1,0,0:127 0/0:0,3,42:1,0:1,0,0:127 0/0:0,12,142:4,0:1,0,0:127 0/0:0,6,67:2,0:1,0,0:127 0/0:0,3,39:1,0:1,0,0:127 0/0:0,6,54:2,0:1,0,0:127 bcftools-1.21/test/call.af-fixation.txt000066400000000000000000000011231467060157400201160ustar00rootroot00000000000000NA07051_CEU CEU NA12843_CEU CEU NA18488_YRI YRI NA18489_YRI YRI NA18498_YRI YRI NA18504_YRI YRI NA18510_YRI YRI NA18519_YRI YRI NA18858_YRI YRI NA18861_YRI YRI NA18868_YRI YRI NA18871_YRI YRI NA18874_YRI YRI NA18881_YRI YRI NA18907_YRI YRI NA18909_YRI YRI NA18917_YRI YRI NA18933_YRI YRI NA18934_YRI YRI NA19108_YRI YRI NA19119_YRI YRI NA19129_YRI YRI NA19131_YRI YRI NA19138_YRI YRI NA19147_YRI YRI NA19189_YRI YRI NA19197_YRI YRI NA19198_YRI YRI NA19206_YRI YRI NA19214_YRI YRI NA19223_YRI YRI NA19238_YRI YRI NA19239_YRI YRI NA19248_YRI YRI NA19256_YRI YRI bcftools-1.21/test/call.af-fixation.vcf000066400000000000000000000045721467060157400200700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07051_CEU NA12843_CEU NA18488_YRI NA18489_YRI NA18498_YRI NA18504_YRI NA18510_YRI NA18519_YRI NA18858_YRI NA18861_YRI NA18868_YRI NA18871_YRI NA18874_YRI NA18881_YRI NA18907_YRI NA18909_YRI NA18917_YRI NA18933_YRI NA18934_YRI NA19108_YRI NA19119_YRI NA19129_YRI NA19131_YRI NA19138_YRI NA19147_YRI NA19189_YRI NA19197_YRI NA19198_YRI NA19206_YRI NA19214_YRI NA19223_YRI NA19238_YRI NA19239_YRI NA19248_YRI NA19256_YRI 2 136608646 . G A,T,<*> 0 . I16=95,24,45,11,4466,172210,1917,71261,7086,423410,3283,194379,2130,47014,1038,22600;QS=40.8826,20.7918,0.325581,0 PL:AD 32,3,0,32,3,32,32,3,32,32:0,1,0,0 0,3,37,3,37,37,3,37,37,37:1,0,0,0 0,6,77,6,77,77,6,77,77,77:2,0,0,0 0,3,33,3,33,33,3,33,33,33:1,0,0,0 0,6,67,6,67,67,6,67,67,67:2,0,0,0 0,6,67,6,67,67,6,67,67,67:2,0,0,0 0,6,67,6,67,67,6,67,67,67:2,0,0,0 0,3,60,3,60,60,3,60,60,60:1,0,0,0 0,21,147,21,147,147,21,147,147,147:7,0,0,0 0,24,161,24,161,161,24,161,161,161:8,0,0,0 0,6,52,6,52,52,6,52,52,52:2,0,0,0 0,3,38,3,38,38,3,38,38,38:1,0,0,0 0,6,72,6,72,72,6,72,72,72:2,0,0,0 0,18,197,18,197,197,18,197,197,197:6,0,0,0 0,21,175,21,175,175,21,175,175,175:7,0,0,0 0,12,129,12,129,129,12,129,129,129:4,0,0,0 0,21,220,21,220,220,21,220,220,220:7,0,0,0 0,9,111,9,111,111,9,111,111,111:3,0,0,0 0,6,76,6,76,76,6,76,76,76:2,0,0,0 0,15,125,15,125,125,15,125,125,125:5,0,0,0 0,3,32,3,32,32,3,32,32,32:1,0,0,0 0,12,110,12,110,110,12,110,110,110:4,0,0,0 0,3,41,3,41,41,3,41,41,41:1,0,0,0 0,12,124,12,124,124,12,124,124,124:4,0,0,0 0,6,70,6,70,70,6,70,70,70:2,0,0,0 0,18,140,18,140,140,18,140,140,140:6,0,0,0 0,3,22,3,22,22,3,22,22,22:1,0,0,0 0,6,63,6,63,63,6,63,63,63:2,0,0,0 0,3,46,3,46,46,3,46,46,46:1,0,0,0 0,3,39,3,39,39,3,39,39,39:1,0,0,0 0,3,42,3,42,42,3,42,42,42:1,0,0,0 0,12,142,12,142,142,12,142,142,142:4,0,0,0 0,6,67,6,67,67,6,67,67,67:2,0,0,0 0,3,39,3,39,39,3,39,39,39:1,0,0,0 0,6,54,6,54,54,6,54,54,54:2,0,0,0 bcftools-1.21/test/check.chk000066400000000000000000000114651467060157400160140ustar00rootroot00000000000000# # Definition of sets: # ID [2]id [3]tab-separated file names # SN, Summary numbers: # number of records .. number of data rows in the VCF # number of no-ALTs .. reference-only sites, ALT is either "." or identical to REF # number of SNPs .. number of rows with a SNP # number of MNPs .. number of rows with a MNP, such as CC>TT # number of indels .. number of rows with an indel # number of others .. number of rows with other type, for example a symbolic allele or # a complex substitution, such as ACT>TCGA # number of multiallelic sites .. number of rows with multiple alternate alleles # number of multiallelic SNP sites .. number of rows with multiple alternate alleles, all SNPs # # Note that rows containing multiple types will be counted multiple times, in each # counter. For example, a row with a SNP and an indel increments both the SNP and # the indel counter. # # SN [2]id [3]key [4]value SN 0 number of samples: 2 SN 0 number of records: 18 SN 0 number of no-ALTs: 1 SN 0 number of SNPs: 5 SN 0 number of MNPs: 1 SN 0 number of indels: 9 SN 0 number of others: 2 SN 0 number of multiallelic sites: 6 SN 0 number of multiallelic SNP sites: 1 # TSTV, transitions/transversions # - transitions, see https://en.wikipedia.org/wiki/Transition_(genetics) # - transversions, see https://en.wikipedia.org/wiki/Transversion # TSTV [2]id [3]ts [4]tv [5]ts/tv [6]ts (1st ALT) [7]tv (1st ALT) [8]ts/tv (1st ALT) TSTV 0 3 2 1.50 3 1 3.00 # SiS, Singleton stats: # - allele count, i.e. the number of singleton genotypes (AC=1) # - number of transitions, see above # - number of transversions, see above # - repeat-consistent, inconsistent and n/a: experimental and useless stats [DEPRECATED] # SiS [2]id [3]allele count [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable SiS 0 1 3 1 2 0 0 0 0 # AF, Stats by non-reference allele frequency: # AF [2]id [3]allele frequency [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable AF 0 0.000000 3 1 2 2 0 0 2 AF 0 0.490000 0 0 0 12 0 0 12 AF 0 0.740000 1 1 0 0 0 0 0 AF 0 0.990000 1 1 0 0 0 0 0 # QUAL, Stats by quality # QUAL [2]id [3]Quality [4]number of SNPs [5]number of transitions (1st ALT) [6]number of transversions (1st ALT) [7]number of indels QUAL 0 12.6 1 0 1 0 QUAL 0 12.9 0 0 0 1 QUAL 0 45.0 0 0 0 1 QUAL 0 59.2 1 1 0 0 QUAL 0 59.9 0 0 0 3 QUAL 0 60.2 1 1 0 0 QUAL 0 61.5 0 0 0 1 QUAL 0 79.0 0 0 0 1 QUAL 0 82.7 0 0 0 1 QUAL 0 90.6 1 1 0 0 QUAL 0 342.0 0 0 0 1 # IDD, InDel distribution: # IDD [2]id [3]length (deletions negative) [4]number of sites [5]number of genotypes [6]mean VAF IDD 0 -10 1 0 . IDD 0 -8 1 0 . IDD 0 -4 3 0 . IDD 0 -3 4 0 . IDD 0 -2 1 0 . IDD 0 -1 2 0 . IDD 0 1 1 0 . IDD 0 2 1 0 . # ST, Substitution types: # ST [2]id [3]type [4]count ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 0 ST 0 C>G 0 ST 0 C>T 0 ST 0 G>A 3 ST 0 G>C 1 ST 0 G>T 1 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 # DP, depth: # - set id, see above # - the depth bin, corresponds to the depth (unless --depth was given) # - number of genotypes with this depth (zero unless -s/-S was given) # - fraction of genotypes with this depth (zero unless -s/-S was given) # - number of sites with this depth # - fraction of sites with this depth # DP, Depth distribution # DP [2]id [3]bin [4]number of genotypes [5]fraction of genotypes (%) [6]number of sites [7]fraction of sites (%) DP 0 10 2 5.555556 0 0.000000 DP 0 21 2 5.555556 0 0.000000 DP 0 22 2 5.555556 0 0.000000 DP 0 26 4 11.111111 0 0.000000 DP 0 30 2 5.555556 0 0.000000 DP 0 31 16 44.444444 0 0.000000 DP 0 32 4 11.111111 0 0.000000 DP 0 35 4 11.111111 0 0.000000 DP 0 60 0 0.000000 1 33.333333 DP 0 62 0 0.000000 2 66.666667 # PSC, Per-sample counts. Note that the ref/het/hom counts include only SNPs, for indels see PSI. The rest include both SNPs and indels. # PSC [2]id [3]sample [4]nRefHom [5]nNonRefHom [6]nHets [7]nTransitions [8]nTransversions [9]nIndels [10]average depth [11]nSingletons [12]nHapRef [13]nHapAlt [14]nMissing PSC 0 A 0 2 4 3 2 9 28.7 1 0 0 0 PSC 0 B 1 1 4 2 2 9 28.7 0 0 0 0 # PSI, Per-Sample Indels. Note that alt-het genotypes with both ins and del allele are counted twice, in both nInsHets and nDelHets. # PSI [2]id [3]sample [4]in-frame [5]out-frame [6]not applicable [7]out/(in+out) ratio [8]nInsHets [9]nDelHets [10]nInsAltHoms [11]nDelAltHoms PSI 0 A 0 0 0 0.00 1 8 0 0 PSI 0 B 0 0 0 0.00 1 8 0 0 # HWE # HWE [2]id [3]1st ALT allele frequency [4]Number of observations [5]25th percentile [6]median [7]75th percentile HWE 0 0.000000 2 0.490000 0.490000 0.990000 HWE 0 0.490000 14 0.990000 0.990000 0.990000 HWE 0 0.740000 1 0.490000 0.490000 0.490000 HWE 0 0.990000 1 0.000000 0.000000 0.000000 bcftools-1.21/test/check.gs.chrom.gen000066400000000000000000000012021467060157400175230ustar00rootroot000000000000001 1:3062915_GTTT_G 1:3062915_GTTT_G 3062915 GTTT G 0 1 0 0 1 0 1 1:3106154_CAAA_C 1:3106154_CAAA_C 3106154 CAAA C 0 1 0 0 1 0 1 1:3157410_G_A 1:3157410_G_A 3157410 G A 0 0 1 0 0 1 1 1:3162006_G_A 1:3162006_G_A 3162006 G A 0 0 1 0 1 0 1 1:3177144_GT_G 1:3177144_GT_G 3177144 GT G 0 1 0 0 1 0 4 4:3258448_TACACACAC_T 4:3258448_TACACACAC_T 3258448 TACACACAC T 0 1 0 0 1 0 4 4:3258451_AAA_AGT 4:3258451_AAA_AGT 3258451 AAA AGT 0 1 0 0 1 0 4 4:3258452_AAA_AGA 4:3258452_AAA_AGA 3258452 AAA AGA 0 1 0 0 1 0 4 4:3258453_AACA_AGA 4:3258453_AACA_AGA 3258453 AACA AGA 0 1 0 0 1 0 4 4:3258454_AACA_AACA 4:3258454_AACA_AACA 3258454 AACA AACA 0 1 0 0 1 0 bcftools-1.21/test/check.gs.chrom.samples000066400000000000000000000000441467060157400204210ustar00rootroot00000000000000ID_1 ID_2 missing 0 0 0 A A 0 B B 0 bcftools-1.21/test/check.gs.vcfids.gen000066400000000000000000000007271467060157400177040ustar00rootroot000000000000001:3062915_GTTT_G id3D 3062915 GTTT G 0 1 0 0 1 0 1:3106154_CAAA_C . 3106154 CAAA C 0 1 0 0 1 0 1:3157410_G_A . 3157410 G A 0 0 1 0 0 1 1:3162006_G_A . 3162006 G A 0 0 1 0 1 0 1:3177144_GT_G . 3177144 GT G 0 1 0 0 1 0 4:3258448_TACACACAC_T . 3258448 TACACACAC T 0 1 0 0 1 0 4:3258451_AAA_AGT . 3258451 AAA AGT 0 1 0 0 1 0 4:3258452_AAA_AGA . 3258452 AAA AGA 0 1 0 0 1 0 4:3258453_AACA_AGA . 3258453 AACA AGA 0 1 0 0 1 0 4:3258454_AACA_AACA . 3258454 AACA AACA 0 1 0 0 1 0 bcftools-1.21/test/check.gs.vcfids.samples000066400000000000000000000000441467060157400205670ustar00rootroot00000000000000ID_1 ID_2 missing 0 0 0 A A 0 B B 0 bcftools-1.21/test/check.gs.vcfids_chrom.gen000066400000000000000000000007531467060157400210730ustar00rootroot000000000000001 1:3062915_GTTT_G id3D 3062915 GTTT G 0 1 0 0 1 0 1 1:3106154_CAAA_C . 3106154 CAAA C 0 1 0 0 1 0 1 1:3157410_G_A . 3157410 G A 0 0 1 0 0 1 1 1:3162006_G_A . 3162006 G A 0 0 1 0 1 0 1 1:3177144_GT_G . 3177144 GT G 0 1 0 0 1 0 4 4:3258448_TACACACAC_T . 3258448 TACACACAC T 0 1 0 0 1 0 4 4:3258451_AAA_AGT . 3258451 AAA AGT 0 1 0 0 1 0 4 4:3258452_AAA_AGA . 3258452 AAA AGA 0 1 0 0 1 0 4 4:3258453_AACA_AGA . 3258453 AACA AGA 0 1 0 0 1 0 4 4:3258454_AACA_AACA . 3258454 AACA AACA 0 1 0 0 1 0 bcftools-1.21/test/check.gs.vcfids_chrom.samples000066400000000000000000000000441467060157400217570ustar00rootroot00000000000000ID_1 ID_2 missing 0 0 0 A A 0 B B 0 bcftools-1.21/test/check.vcf000066400000000000000000000052661467060157400160270ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:409:35:-20,-5,-20,-20,-5,-20 1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3106154 . G A 59.2 PASS AN=4;AC=1 GT:GQ:DP 0/1:245:32 0/0:245:32 1 3157410 . G A 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . G A 60.2 PASS AN=4;AC=3 GT:GQ:DP 1/1:212:22 0/1:212:22 1 3177144 . GT G 45 PASS AN=4;AC=2 GT:GQ:DP 0/1:150:30 0/1:150:30 1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:10 2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 4 3258448 . TACACACAC T 59.9 PASS DP=62;AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258449 . GCAAA GA,G 59.9 PASS DP=62;AN=4;AC=2,0 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258450 . AAAAGAAAAAG A,AAAAAAG 59.9 PASS DP=60;AN=4;AC=2,0 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258451 . AAA AGT 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258452 . AAA AGA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258453 . AACA AGA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258453 . ACA AAGA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 4 3258454 . AACA AACA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 bcftools-1.21/test/check_merge.chk000066400000000000000000000040501467060157400171630ustar00rootroot00000000000000# # Definition of sets # ID [2]id [3]tab-separated file names # SN, Summary numbers # SN [2]id [3]key [4]value SN 0 number of samples: 2 SN 0 number of records: 18 SN 0 number of no-ALTs: 1 SN 0 number of SNPs: 5 SN 0 number of MNPs: 1 SN 0 number of indels: 9 SN 0 number of others: 2 SN 0 number of multiallelic sites: 6 SN 0 number of multiallelic SNP sites: 1 # # TSTV, transition/transversions: # TSTV [2]id [3]ts [4]tv [5]ts/tv [6]ts (1st ALT) [7]tv (1st ALT) [8]ts/tv (1st ALT) TSTV 0 3 2 1.50 3 1 3.00 # Sis, Singleton stats # SiS [2]id [3]allele count [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable SiS 0 1 3 1 2 0 0 0 0 # AF, Stats by non-reference allele frequency # AF [2]id [3]allele frequency [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable AF 0 0.000000 3 1 2 2 0 0 2 AF 0 0.490000 0 0 0 12 0 0 12 AF 0 0.740000 1 1 0 0 0 0 0 AF 0 0.990000 1 1 0 0 0 0 0 # IDD, InDel distribution # IDD [2]id [3]length (deletions negative) [4]number of sites [5]number of genotypes [6]mean VAF IDD 0 -10 1 0 . IDD 0 -8 1 0 . IDD 0 -4 3 0 . IDD 0 -3 4 0 . IDD 0 -2 1 0 . IDD 0 -1 2 0 . IDD 0 1 1 0 . IDD 0 2 1 0 . # ST, Substitution types # ST [2]id [3]type [4]count ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 0 ST 0 C>G 0 ST 0 C>T 0 ST 0 G>A 3 ST 0 G>C 1 ST 0 G>T 1 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 # DP, Depth distribution # DP [2]id [3]bin [4]number of genotypes [5]fraction of genotypes (%) [6]number of sites [7]fraction of sites (%) DP 0 60 0 0.000000 1 33.333333 DP 0 62 0 0.000000 2 66.666667 # QUAL, Stats by quality # QUAL [2]id [3]Quality [4]number of SNPs [5]number of transitions (1st ALT) [6]number of transversions (1st ALT) [7]number of indels QUAL 0 12.6 1 0 1 0 QUAL 0 12.9 0 0 0 1 QUAL 0 45.0 0 0 0 1 QUAL 0 59.2 1 1 0 0 QUAL 0 59.9 0 0 0 3 QUAL 0 60.2 1 1 0 0 QUAL 0 61.5 0 0 0 1 QUAL 0 79.0 0 0 0 1 QUAL 0 82.7 0 0 0 1 QUAL 0 90.6 1 1 0 0 QUAL 0 342.0 0 0 0 1 bcftools-1.21/test/checkploidy.2.out000066400000000000000000000001161467060157400174260ustar00rootroot00000000000000# [1]Sample [2]Chromosome [3]Region Start [4]Region End [5]Ploidy S1 20 1 1 2 bcftools-1.21/test/checkploidy.2.vcf000066400000000000000000000005431467060157400174010ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FORMAT= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 20 1 1 C G . PASS . GT 0/0 21 1 2 C G . PASS . GT ./0 22 1 3 C G . PASS . GT ./. X 1 4 C G . PASS . GT . bcftools-1.21/test/checkploidy.3.out000066400000000000000000000001611467060157400174270ustar00rootroot00000000000000# [1]Sample [2]Chromosome [3]Region Start [4]Region End [5]Ploidy S1 20 1 1 2 S1 21 1 1 2 S1 22 1 1 2 S1 X 1 1 1 bcftools-1.21/test/checkploidy.out000066400000000000000000000001311467060157400172630ustar00rootroot00000000000000# [1]Sample [2]Chromosome [3]Region Start [4]Region End [5]Ploidy S1 22 1 1 2 S1 X 1 1 1 bcftools-1.21/test/checkploidy.vcf000066400000000000000000000003611467060157400172370ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FORMAT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 22 1 1 C G . PASS . GT 1/1 X 1 2 C G . PASS . GT 1 bcftools-1.21/test/concat.1.a.vcf000066400000000000000000000031231467060157400165650ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##samtoolsVersion=0.2.0-rc10+htslib-0.2.0-rc10 ##samtoolsCommand=samtools mpileup -t INFO/DPR -C50 -pm3 -F0.2 -d10000 -ug -r 1:1-1000000 -b mpileup.2014-07-03//lists/chr1-pooled.list -f human_g1k_v37.fasta ##ALT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 100 . GTTT G 1806 q10 XX=11;DP=35 GT:GQ:DP 0/1:409:35 1 110 . C T,G 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 1 110 . CAAA C 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . G T 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 1 130 . GAA GG 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 1 150 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 1 160 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 bcftools-1.21/test/concat.1.b.vcf000066400000000000000000000017251467060157400165740ustar00rootroot00000000000000##fileformat=VCFv4.0 ##samtoolsVersion=0.2.0-rc10+htslib-0.2.0-rc10 ##samtoolsCommand=samtools mpileup -t INFO/DPR -C50 -pm3 -F0.2 -d10000 -ug -r 1:1-1000000 -b mpileup.2014-07-03//lists/chr1-pooled.list -f human_g1k_v37.fasta ##ALT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 3 142 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 3 152 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 3 162 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 3 172 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 3 182 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 3 192 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 bcftools-1.21/test/concat.1.bcf.out000066400000000000000000000037211467060157400171340ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##FILTER= ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##samtoolsVersion=0.2.0-rc10+htslib-0.2.0-rc10 ##samtoolsCommand=samtools mpileup -t INFO/DPR -C50 -pm3 -F0.2 -d10000 -ug -r 1:1-1000000 -b mpileup.2014-07-03//lists/chr1-pooled.list -f human_g1k_v37.fasta ##ALT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 100 . GTTT G 1806 q10 XX=11;DP=35 GT:GQ:DP 0/1:409:35 1 110 . C T,G 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 1 110 . CAAA C 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . G T 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 1 130 . GAA GG 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 1 150 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 1 160 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 3 142 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 3 152 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 3 162 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 3 172 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 3 182 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 3 192 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 bcftools-1.21/test/concat.1.vcf.out000066400000000000000000000037211467060157400171600ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##FILTER= ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##samtoolsVersion=0.2.0-rc10+htslib-0.2.0-rc10 ##samtoolsCommand=samtools mpileup -t INFO/DPR -C50 -pm3 -F0.2 -d10000 -ug -r 1:1-1000000 -b mpileup.2014-07-03//lists/chr1-pooled.list -f human_g1k_v37.fasta ##ALT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 100 . GTTT G 1806 q10 XX=11;DP=35 GT:GQ:DP 0/1:409:35 1 110 . C T,G 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 1 110 . CAAA C 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . G T 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 1 130 . GAA GG 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 1 150 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 1 160 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 3 142 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 3 152 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 3 162 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 3 172 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 3 182 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 3 192 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 bcftools-1.21/test/concat.2.a.vcf000066400000000000000000000013471467060157400165740ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2 140 . A G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 1 110 . C T,G 1792 Fail XX=11;DP=32 GT:GQ:DP 0/1:245:32 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 bcftools-1.21/test/concat.2.b.vcf000066400000000000000000000022521467060157400165710ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 bcftools-1.21/test/concat.2.bcf.out000066400000000000000000000030761467060157400171400ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 1 110 . C T,G 1792 Fail XX=11;DP=32 GT:GQ:DP 0/1:245:32 1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 140 . 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TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 bcftools-1.21/test/concat.3.0.vcf000066400000000000000000000006321467060157400165100ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B bcftools-1.21/test/concat.3.a.vcf000066400000000000000000000026061467060157400165740ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 9 202 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0|1:409:35 0|1 9 212 . C T,G 1792 PASS DP=32 GT:GQ:DP 0|1:245:32 0|1 9 212 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0|1:245:32 0|1 9 222 . GA G 628 q10 DP=21 GT:GQ:DP 0|1:21:21 0|1 9 232 . G T 1016 PASS DP=22 GT:GQ:DP 0|1:212:22 0|1 9 232 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0|1:212:22 0|1 9 242 . GT G 727 PASS DP=30 GT:GQ:DP 0|1:150:30 0|1 9 252 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 0|1:12:10 0|1 9 262 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 0|1:12:10 0|1 1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0|1:409:35 0|1 1 110 . C T,G 1792 PASS DP=32 GT:GQ:DP 0|1:245:32 0|1 1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0|1:245:32 0|1 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 0|1:21:21 0|1 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0|1:212:22 0|1 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0|1:212:22 0|1 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0|1:150:30 0|1 1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 0|1:12:10 0|1 1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 0|1:12:10 0|1 bcftools-1.21/test/concat.3.b.vcf000066400000000000000000000364241467060157400166020ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2 170 . 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T A 246 PASS DP=10 GT 1|0 0|1 bcftools-1.21/test/concat.3.bcf.out000066400000000000000000000440311467060157400171350ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 9 202 . 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GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 1 140 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:100 0|1:.:.:100 1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 2 170 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 180 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 190 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 200 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 210 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 220 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 230 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 240 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 250 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 260 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 270 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 280 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 290 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 300 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 310 . T A 246 PASS DP=10 GT:PQ:PS 1|0:3:310 0|1:28:310 2 320 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 330 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 340 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 350 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 360 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 370 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 2 380 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 390 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 490 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 500 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 510 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 3 380 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 390 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 400 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 410 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 420 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 430 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 440 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 450 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 460 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 470 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 480 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 490 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 bcftools-1.21/test/concat.3.c.vcf000066400000000000000000000016561467060157400166020ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2 280 . T A 246 PASS DP=10 GT 1|0 0|1 2 290 . T A 246 PASS DP=10 GT 1|0 1|0 2 300 . T A 246 PASS DP=10 GT 0|1 1|0 2 310 . T A 246 PASS DP=10 GT 0|1 1|0 2 320 . T A 246 PASS DP=10 GT 0|1 1|0 2 330 . T A 246 PASS DP=10 GT 0|1 1|0 2 340 . T A 246 PASS DP=10 GT 0|1 1|0 2 350 . T A 246 PASS DP=10 GT 0|1 1|0 2 360 . T A 246 PASS DP=10 GT 0|1 1|0 2 370 . T A 246 PASS DP=10 GT 0|1 1|0 2 380 . T A 246 PASS DP=10 GT 0|1 1|0 2 390 . T A 246 PASS DP=10 GT 0|1 1|0 2 400 . T A 246 PASS DP=10 GT 0|1 1|0 2 410 . 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T A 246 PASS DP=10 GT 0|1 0|1 2 320 . T A 246 PASS DP=10 GT 0|1 0|1 2 330 . T A 246 PASS DP=10 GT 0|1 0|1 2 340 . T A 246 PASS DP=10 GT 0|1 0|1 2 350 . T A 246 PASS DP=10 GT 0|1 0|1 2 360 . T A 246 PASS DP=10 GT 0|1 0|1 2 370 . T A 246 PASS DP=10 GT 0|1 0|1 2 380 . T A 246 PASS DP=10 GT 0|1 0|1 2 390 . T A 246 PASS DP=10 GT 0|1 0|1 2 490 . T A 246 PASS DP=10 GT 0|1 0|1 2 500 . T A 246 PASS DP=10 GT 0|1 0|1 2 510 . T A 246 PASS DP=10 GT 0|1 0|1 bcftools-1.21/test/concat.3.f.vcf000066400000000000000000000015421467060157400165770ustar00rootroot00000000000000##fileformat=VCFv4.0 ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 3 380 . T A 246 PASS DP=10 GT 1|0 1|0 3 390 . T A 246 PASS DP=10 GT 1|0 1|0 3 400 . T A 246 PASS DP=10 GT 1|0 1|0 3 410 . T A 246 PASS DP=10 GT 1|0 1|0 3 420 . T A 246 PASS DP=10 GT 1|0 1|0 3 430 . T A 246 PASS DP=10 GT 1|0 1|0 3 440 . T A 246 PASS DP=10 GT 1|0 1|0 3 450 . T A 246 PASS DP=10 GT 1|0 1|0 3 460 . T A 246 PASS DP=10 GT 1|0 1|0 3 470 . T A 246 PASS DP=10 GT 1|0 1|0 3 480 . T A 246 PASS DP=10 GT 1|0 1|0 3 490 . T A 246 PASS DP=10 GT 1|0 1|0 bcftools-1.21/test/concat.3.vcf.out000066400000000000000000000440311467060157400171610ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 9 202 . GTTT G 1806 q10 DP=35 GT:GQ:DP:PS 0|1:409:35:202 0|1:.:.:202 9 212 . C T,G 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:202 0|1:.:.:202 9 212 . CAAA C 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:202 0|1:.:.:202 9 222 . GA G 628 q10 DP=21 GT:GQ:DP:PS 0|1:21:21:202 0|1:.:.:202 9 232 . G T 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:202 0|1:.:.:202 9 232 . GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:202 0|1:.:.:202 9 242 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:202 0|1:.:.:202 9 252 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:202 0|1:.:.:202 9 262 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:202 0|1:.:.:202 1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP:PS 0|1:409:35:100 0|1:.:.:100 1 110 . C T,G 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:100 0|1:.:.:100 1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:100 0|1:.:.:100 1 120 . GA G 628 q10 DP=21 GT:GQ:DP:PS 0|1:21:21:100 0|1:.:.:100 1 130 . G T 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 1 140 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:100 0|1:.:.:100 1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 2 170 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 180 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 190 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 200 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 210 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 220 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 230 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 240 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 250 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 260 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 270 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 280 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 290 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 300 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 2 310 . T A 246 PASS DP=10 GT:PQ:PS 1|0:3:310 0|1:28:310 2 320 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 330 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 340 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 350 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 360 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 370 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 2 380 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 390 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 490 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 500 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 2 510 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 3 380 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 390 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 400 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 410 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 420 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 430 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 440 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 450 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 460 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 470 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 480 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 3 490 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 bcftools-1.21/test/concat.4.a.vcf000066400000000000000000000003161467060157400165710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . A C . . . GT 0|1 chr1 2 . C G . . . GT 0/1 bcftools-1.21/test/concat.4.b.vcf000066400000000000000000000003501467060157400165700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . A C . . . GT 1|0 chr1 2 . C G . . . GT 0/1 chr1 3 . G T . . . GT 0|1 bcftools-1.21/test/concat.4.bcf.out000066400000000000000000000026431467060157400171410ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 1 110 . C T,G 1792 Fail XX=11;DP=32 GT:GQ:DP 0/1:245:32 1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 2 140 . A G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 bcftools-1.21/test/concat.4.vcf.out000066400000000000000000000026431467060157400171650ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 2 140 . A G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 1 110 . C T,G 1792 Fail XX=11;DP=32 GT:GQ:DP 0/1:245:32 1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 bcftools-1.21/test/concat.5.1.out000066400000000000000000000007021467060157400165420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . A C . . . GT:PS 0|1:1 chr1 3 . G T . . . GT:PS 0|1:1 chr1 4 . T A . . . GT:PS 1|0:1 bcftools-1.21/test/concat.5.2.out000066400000000000000000000007471467060157400165540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . A C . . . GT:PS 0|1:1 chr1 2 . C G . . . GT:PS 1|0:1 chr1 3 . G T . . . GT:PQ:PS 0|1:99:1 chr1 4 . T A . . . GT:PS 1|0:1 bcftools-1.21/test/concat.5.3.out000066400000000000000000000003171467060157400165460ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 1 . A C . . . chr1 2 . C G . . . chr1 3 . G T . . . chr1 4 . T A . . . bcftools-1.21/test/concat.5.a.vcf000066400000000000000000000002641467060157400165740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . A C . . . GT 0|1 bcftools-1.21/test/concat.5.b.vcf000066400000000000000000000003161467060157400165730ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 2 . C G . . . GT 1|0 chr1 3 . G T . . . GT 0|1 bcftools-1.21/test/concat.5.c.vcf000066400000000000000000000003161467060157400165740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 3 . G T . . . GT 1|0 chr1 4 . T A . . . GT 0|1 bcftools-1.21/test/concat.5.out000066400000000000000000000007101467060157400164020ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . A C . . . GT:PS 0|1:1 chr1 2 . C G . . . GT:PQ:PS 0/1:99:1 chr1 3 . G T . . . GT:PS 1|0:1 bcftools-1.21/test/consensus.1.chain000066400000000000000000000002041467060157400174200ustar00rootroot00000000000000chain 497 1 501 + 1 501 1 502 + 1 502 1 11 3 1 1 0 3 485 chain 485 2 501 + 0 501 2 495 + 0 495 2 61 3 1 54 3 1 58 0 8 21 10 0 291 bcftools-1.21/test/consensus.1.out000066400000000000000000000020021467060157400171430ustar00rootroot00000000000000>1:2-501 TACAAAATATGATAAAATCAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG AAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TTTAAAAACAAAAAAAAAGAA >2 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AAATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATTTCA GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCT GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTCCAGAC ACAGTTAATCCAGAC bcftools-1.21/test/consensus.10.vcf000066400000000000000000000007241467060157400172030ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00105 14 43616644 . A . . END=43616654 GT 0|0 14 43616653 . T TGAA . . . GT 0|1 bcftools-1.21/test/consensus.11.1.out000066400000000000000000000000321467060157400173640ustar00rootroot00000000000000>1 CGCGCACCCACGTATACGCGTA bcftools-1.21/test/consensus.11.2.out000066400000000000000000000000321467060157400173650ustar00rootroot00000000000000>1 NNNNNNNNNNNNNNTNNNNNNN bcftools-1.21/test/consensus.11.fa000066400000000000000000000000421467060157400170050ustar00rootroot00000000000000>1 CGCGCACCCACGTATACGTGTACACGCGTA bcftools-1.21/test/consensus.11.vcf000066400000000000000000000003661467060157400172060ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl 1 15 . TACGTGTAC T . . . GT 0/1 1 18 . G A . . . GT 0/0 1 19 . T C . . . GT 1/1 bcftools-1.21/test/consensus.12.fa000066400000000000000000000020071467060157400170110ustar00rootroot00000000000000>1:2-501 TACcAtATgTgACAtATAAaAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG cAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA >2 gaagatcttttccttattaaggatctgaagctctgtagatttgtattctattaaacatgg AgagattagtgattttccatattctttaagtcattttagagtaatgtgttcttaagatAa atcagaaaaacaaaaacttgtgctttcctgtttgaaaaacaaacagctgtggggaatgGt gtcgggacagcctttttatAaaatttttctaaataatgttgaggctttgatacgtcaaag ttatatttcaaatggaatcacttagacctcgtttctgagtgtcaatggccatattggggA tttgctgctgccaatgacaGcacaccctgggaatgccccaactacttactacaaagcagt gttacatggagaagatcttcaagagtctttttgctagatctttccttggcttttgatgtg actcctctcaataaaatccacagtaatatagtgagtggtctcctgctccaaaccagtatt Tcagacacagttaatccagac bcftools-1.21/test/consensus.12.out000066400000000000000000000020021467060157400172250ustar00rootroot00000000000000>1:2-501 TACaAaATaTgataaaATCAaAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG aAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA >2 gaagatcttttccttattaaggatctgaagctctgtagatttgtattctattaaacatgg AAattagtgattttccatattctttaagtcattttagagtaatgtgttcttaagatTtca gaaaaacaaaaacttgtgctttcctgtttgaaaaacaaacagctgtggggaatgGACGTA CGTtgtcgggacagcctttttatAaaataatgttgaggctttgatacgtcaaagttatat ttcaaatggaatcacttagacctcgtttctgagtgtcaatggccatattggggAtttgct gctgccaatgacaGcacaccctgggaatgccccaactacttactacaaagcagtgttaca tggagaagatcttcaagagtctttttgctagatctttccttggcttttgatgtgactcct ctcaataaaatccacagtaatatagtgagtggtctcctgctccaaaccagtattCcagac acagttaatccagac bcftools-1.21/test/consensus.12.vcf000066400000000000000000000016651467060157400172120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##INFO= ##ALT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 5 . C A . PASS . GT 0/1 1 5 . C T . PASS . GT 0/1 1 7 . T A . PASS . GT . 1 10 . G A . PASS . GT 0/1 1 12 . GACA GA . PASS . GT 0/1 1 16 . T TAAA . PASS . GT 1/1 1 19 . A C . PASS . GT 0/1 1 61 . C A . PASS . GT 0/1 2 61 . agag aa . PASS . GT 0/1 2 119 . aaa t . PASS . GT 0/1 2 179 . g gacgtacgt . PASS . GT 0/1 2 200 . a . PASS END=210 GT 1/0 2 300 . a . . PASS END=310;MinDP=10 GT 0/1 2 320 . a <*> . PASS END=330;MinDP=20 GT 0/1 2 481 . t c,a . PASS . GT 0/2 bcftools-1.21/test/consensus.13.fa000066400000000000000000000000501467060157400170060ustar00rootroot00000000000000>2 ACGTACGTACGTACGTACGTACGTACGTACGTACGT bcftools-1.21/test/consensus.13.out000066400000000000000000000000421467060157400172300ustar00rootroot00000000000000>2 ACGTACGTAAGTGTACGTACGTACGTACGT bcftools-1.21/test/consensus.13.vcf000066400000000000000000000007541467060157400172110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##ALT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 2 10 . C A . . . GT 0/1 2 10 . C . . END=12 GT 0/1 2 12 . T . . END=14 GT 0/1 2 16 . TAC . . . GT 0/1 bcftools-1.21/test/consensus.14.fa000066400000000000000000000000101467060157400170030ustar00rootroot00000000000000>1 GACT bcftools-1.21/test/consensus.14.out000066400000000000000000000000071467060157400172320ustar00rootroot00000000000000>1 ACT bcftools-1.21/test/consensus.14.vcf000066400000000000000000000002041467060157400172000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=genome.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . GA A . . . bcftools-1.21/test/consensus.15.fa000066400000000000000000000000161467060157400170120ustar00rootroot00000000000000>ref ACGTACGT bcftools-1.21/test/consensus.15.out000066400000000000000000000020221467060157400172320ustar00rootroot00000000000000>1:2-501 TACAAAATATga--tAAAATCAaAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT TGAAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCA TTAAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAA ATATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTC TCTTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAA ACTTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGA AGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATC TGATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAA TCTTTAAAAACAAAAAAAAAGAA >2 gaagatcttttccttattaaggatctgaagctctgtagatttgtattctattaaacatgg AA--attagtgattttccatattctttaagtcattttagagtaatgtgttcttaagatT- -tcagaaaaacaaaaacttgtgctttcctgtttgaaaaacaaacagctgtggggaatgGA CGTACGTtgtcgggacagcctttttatA----------aaataatgttgaggctttgata cgtcaaagttatatttcaaatggaatcacttagacctcgtttctgagtgtcaatggccat attggggAtttgctgctgccaatgacaGcacaccctgggaatgccccaactacttactac aaagcagtgttacatggagaagatcttcaagagtctttttgctagatctttccttggctt ttgatgtgactcctctcaataaaatccacagtaatatagtgagtggtctcctgctccaaa ccagtattCcagacacagttaatccagac bcftools-1.21/test/consensus.15.vcf000066400000000000000000000004471467060157400172120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample ref 3 . GT CC . PASS . GT 0/1 ref 5 . A C,CT . PASS . GT 0/2 ref 7 . G GC,GT . PASS . GT 1/2 bcftools-1.21/test/consensus.16.out000066400000000000000000000020021467060157400172310ustar00rootroot00000000000000>1:2-501 TACMAWATRTGATAAAATMAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG MAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx TTTAAAAACAAAAAAAAAGAA >2 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ARATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATWTCA GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxTTTGCT GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTHCAGAC ACAGTTAATCCAGAC bcftools-1.21/test/consensus.16.vcf000066400000000000000000000015071467060157400172110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##ALT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 5 . C a . PASS . GT 0/1 1 5 . C t . PASS . GT 0/1 1 7 . T a . PASS . GT 0/1 1 10 . G a . PASS . GT 0/1 1 12 . GACA ga . PASS . GT 0/1 1 16 . T taaa . PASS . GT 0/1 1 19 . A c . PASS . GT 0/1 1 61 . C a . PASS . GT 0/1 2 61 . AGAG aa . PASS . GT 0/1 2 119 . AAA t . PASS . GT 0/1 2 179 . G gacgtacgt . PASS . GT 0/1 2 200 . A . PASS END=210 GT 1/0 2 481 . T c,a . PASS . GT 0/1/2 2 484 . G cc,aa . PASS . GT 0/1/2 bcftools-1.21/test/consensus.17.bed000066400000000000000000000000351467060157400171610ustar00rootroot000000000000001 0 59 2 0 60 3 0 30 4 31 62 bcftools-1.21/test/consensus.17.out000066400000000000000000000000201467060157400172300ustar00rootroot00000000000000>ref ACsymtCGyT bcftools-1.21/test/consensus.17.vcf000066400000000000000000000003451467060157400172110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 bcftools-1.21/test/consensus.18.fa000066400000000000000000000010011467060157400170100ustar00rootroot00000000000000>1 TACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTGC CAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA bcftools-1.21/test/consensus.18.out000066400000000000000000000020031467060157400172340ustar00rootroot00000000000000>1:2-501 TACMAWATRTGATAAAATMAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG MAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA >2 GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG ARATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATWTCA GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGTTATAT TTCAAATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGATTTGCT GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTHCAVMA CACAGTTAATCCAGAC bcftools-1.21/test/consensus.18.vcf000066400000000000000000000014561467060157400172160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##ALT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 1 . T . . END=1 GT 0/0 1 2 . A . . END=2 GT 0/0 1 3 . C . . END=11 GT 0/0 1 12 . A . . END=21 GT 0/0 1 22 . A . . END=23 GT 0/0 1 24 . G . . END=25 GT 0/0 1 26 . A . . END=26 GT 0/0 1 27 . C . . END=29 GT 0/0 1 30 . A C, . . . GT 1/1 1 31 . A . . END=31 GT 0/0 1 32 . C . . END=43 GT 0/0 1 44 . C . . END=48 GT 0/0 bcftools-1.21/test/consensus.19.fa000066400000000000000000000002071467060157400170200ustar00rootroot00000000000000>chr19:1048895-1049005 GCCAGTACGGGATCCCTGAACCATGGAATTTTCCTTTTCGGAGGAGCTACTGGTGCGGACCTCGGCCCCCCAAGAGTCCAGCCCCTTGCCCCACCCCGCTGGACCCAAAGG bcftools-1.21/test/consensus.19.out000066400000000000000000000020221467060157400172360ustar00rootroot00000000000000>1:2-501 TAC:A:AT:Tga::t+++AT:AaAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT TG:AGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCA TTAAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAA ATATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTC TCTTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAA ACTTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGA AGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATC TGATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAA TCTTTAAAAACAAAAAAAAAGAA >2 gaagatcttttccttattaaggatctgaagctctgtagatttgtattctattaaacatgg A:::attagtgattttccatattctttaagtcattttagagtaatgtgttcttaagat:: :tcagaaaaacaaaaacttgtgctttcctgtttgaaaaacaaacagctgtggggaatgG+ +++++++tgtcgggacagcctttttatA----------aaataatgttgaggctttgata cgtcaaagttatatttcaaatggaatcacttagacctcgtttctgagtgtcaatggccat attggggAtttgctgctgccaatgacaGcacaccctgggaatgccccaactacttactac aaagcagtgttacatggagaagatcttcaagagtctttttgctagatctttccttggctt ttgatgtgactcctctcaataaaatccacagtaatatagtgagtggtctcctgctccaaa ccagtatt:cagacacagttaatccagac bcftools-1.21/test/consensus.19.vcf000066400000000000000000000014431467060157400172130ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##FORMAT= ##INFO= ##ALT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 chr19 1048985 . C . . END=1048985 GT 0/0 chr19 1048986 . C . . END=1048994 GT 0/0 chr19 1048995 . G . . END=1049004 GT 0/0 chr19 1049005 . G . . END=1049006 GT 0/0 chr19 1049007 . T . . END=1049008 GT 0/0 chr19 1049009 . A . . END=1049009 GT 0/0 chr19 1049010 . G . . END=1049012 GT 0/0 chr19 1049013 . A C, . . . GT 1/1 chr19 1049014 . C . . END=1049014 GT 0/0 bcftools-1.21/test/consensus.2.chain000066400000000000000000000001521467060157400174230ustar00rootroot00000000000000chain 500 1 501 + 1 501 1 504 + 1 504 1 15 0 3 485 chain 491 2 501 + 0 501 2 491 + 0 491 2 200 10 0 291 bcftools-1.21/test/consensus.2.out000066400000000000000000000020001467060157400171420ustar00rootroot00000000000000>1:2-501 TACCATATGTGACATAAAATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT TGCAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCA TTAAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAA ATATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTC TCTTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAA ACTTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGA AGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATC TGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNTTTAAAAACAAAAAAAAAGAA >2 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT GTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCTGCTG CCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACATGGA GAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCTCTCA ATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTTCAGACACAG TTAATCCAGAC bcftools-1.21/test/consensus.20.fa000066400000000000000000000000161467060157400170060ustar00rootroot00000000000000>ref ACGTACGT bcftools-1.21/test/consensus.20.vcf000066400000000000000000000004731467060157400172050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b ref 2 . C A . . . GT ./. 0/0 ref 3 . G C . . . GT 0/0 0/0 ref 4 . T C . . . GT 0/0 0/1 ref 5 . A C . . . GT 1/1 1/1 bcftools-1.21/test/consensus.21.fa000066400000000000000000000000471467060157400170130ustar00rootroot00000000000000>17 ACGTACGT >18 ACGTACGT >19 ACGTACGT bcftools-1.21/test/consensus.21.vcf000066400000000000000000000005061467060157400172030ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a 19 2 . C A . . . GT 0/0 19 3 . G C . . . GT 0/0 19 4 . T C . . . GT 0/1 19 5 . A C . . . GT 1/1 bcftools-1.21/test/consensus.22.fa000066400000000000000000000001321467060157400170070ustar00rootroot00000000000000>1:11-19 ACGTACGT >2:11-19 ACGTACGT >3:11-19 ACGTACGT >4:11-19 ACGTACGT >5:11-19 ACGTACGT bcftools-1.21/test/consensus.22.vcf000066400000000000000000000011571467060157400172070ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a 1 8 . ACGA A . . . GT 1/1 1 12 . C A . . . GT 1/1 2 8 . ACGA TTTT . . . GT 1/1 2 12 . C A . . . GT 1/1 3 10 . A T . . . GT 1/1 3 12 . C A . . . GT 1/1 4 8 . A . . END=11 GT 1/1 4 12 . C A . . . GT 1/1 5 8 . ACGA ACG . . . GT 1/1 5 12 . C A . . . GT 1/1 bcftools-1.21/test/consensus.3.chain000066400000000000000000000002041467060157400174220ustar00rootroot00000000000000chain 497 1 501 + 1 501 1 502 + 1 502 1 11 3 1 1 0 3 485 chain 485 2 501 + 0 501 2 495 + 0 495 2 61 3 1 54 3 1 58 0 8 21 10 0 291 bcftools-1.21/test/consensus.3.out000066400000000000000000000020021467060157400171450ustar00rootroot00000000000000>1:2-501 TACMAWATRTGATAAAATMAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG MAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TTTAAAAACAAAAAAAAAGAA >2 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ARATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATWTCA GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCT GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTHCAGAC ACAGTTAATCCAGAC bcftools-1.21/test/consensus.4.chain000066400000000000000000000001521467060157400174250ustar00rootroot00000000000000chain 500 1 501 + 1 501 1 504 + 1 504 1 15 0 3 485 chain 491 2 501 + 0 501 2 491 + 0 491 2 200 10 0 291 bcftools-1.21/test/consensus.4.out000066400000000000000000000020001467060157400171440ustar00rootroot00000000000000>1:2-501 TACCATATGTGACATAAAATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT TGCAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCA TTAAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAA ATATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTC TCTTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAA ACTTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGA AGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATC TGATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAA TCTTTAAAAACAAAAAAAAAGAA >2 GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT GTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGTTATATTTCA AATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGATTTGCTGCTG CCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACATGGA GAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCTCTCA ATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTTCAGACACAG TTAATCCAGAC bcftools-1.21/test/consensus.5.out000066400000000000000000000020071467060157400171540ustar00rootroot00000000000000>1:2-501 TACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTGC AGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATTA AATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAATA TTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTCT TGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAACT TCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAGG TCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTGA TGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATCT TTAAAAACAAAAAAAAAGAA >2 GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT GTCGGGACAGCCTTTTTATAAAATTTTTCTAAATAATGTTGAGGCTTTGATACGTCAAAG TTATATTTCAAATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGA TTTGCTGCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGT GTTACATGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTG ACTCCTCTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATT TCAGACACAGTTAATCCAGAC bcftools-1.21/test/consensus.8a.out000066400000000000000000000020021467060157400173130ustar00rootroot00000000000000>1:2-501 TACAAAATATGATAAAATCAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG AAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA >2 GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG AAATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATTTCA GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGTTATAT TTCAAATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGATTTGCT GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTCCAGAC ACAGTTAATCCAGAC bcftools-1.21/test/consensus.8b.out000066400000000000000000000020021467060157400173140ustar00rootroot00000000000000>1:2-501 ...A.A..A.GATAAA..C......................................... A........................................................... ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ..................... >2 ............................................................ AA......................................................T... ......................................................GACGTA CGT....................A.................................... .....................................................ATTTGCT GCTG.........GCACACCCTGG.................................... ............................................................ ......................................................C..... ............... bcftools-1.21/test/consensus.8c.out000066400000000000000000000020071467060157400173220ustar00rootroot00000000000000>1:2-501 ...A.A..A........C.........................................A ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ .................... >2 ............................................................ ............................................................ ............................................................ ............................................................ ...........................................................A TTTGCTGCTG.........GCACACCCTGG.............................. ............................................................ ............................................................ C.................... bcftools-1.21/test/consensus.8d.out000066400000000000000000000020141467060157400173210ustar00rootroot00000000000000>1:2-501 ...A.A..A.GATAAA..C......................................... A........................................................... ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ..................... >2 ............................................................ AA......................................................T... ......................................................GACGTA CGT......................................................... ............................................................ ...ATTTGCTGCTG.........GCACACCCTGG.......................... ............................................................ ............................................................ ....C.................... bcftools-1.21/test/consensus.8e.out000066400000000000000000000020021467060157400173170ustar00rootroot00000000000000>1:2-501 ...A.A..A.GATAAA..C......................................... A........................................................... ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ..................... >2 ............................................................ AA......................................................T... ......................................................GACGTA CGT....................A.................................... .....................................................ATTTGCT GCTG........................................................ ............................................................ ......................................................C..... ............... bcftools-1.21/test/consensus.8f.out000066400000000000000000000020021467060157400173200ustar00rootroot00000000000000>1:2-501 ...A.A..A.GATAAA..C......................................... A........................................................... ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ............................................................ ..................... >2 ............................................................ AA......................................................T... ......................................................GACGTA CGT....................A.................................... ............................................................ .............GCACACCCTGG.................................... ............................................................ ......................................................C..... ............... bcftools-1.21/test/consensus.9.1.fa000066400000000000000000000003461467060157400171020ustar00rootroot00000000000000>14:43263973-43263995 GAGGGTGAGCAGAAGCAGGGTGG >14:43308392-43308414 CCTTTCTTTCCTGCTCTGAAGCT >14:43442685-43442707 CCCGTCTTCTTCGTTGCTCAGGC >14:43616643-43616665 GAGTGGGAGCTGAAGAAGTAGAT >14:44474477-44474499 GAGGAGGAGGAGAAGAAGAAGAA bcftools-1.21/test/consensus.9.1.out000066400000000000000000000003511467060157400173170ustar00rootroot00000000000000>14:43263973-43263995 GAGGGTGAGCAGAAGCAGGGTGG >14:43308392-43308414 CCTTTCTTTCCTGCTCTGAAGCT >14:43442685-43442707 CCCGTCTTCTTCGTTGCTCAGGC >14:43616643-43616665 GAGTGGGAGCTGAAGAAGAAGTAGAT >14:44474477-44474499 GAGGAGGAGGAGAAGAAGAAGAA bcftools-1.21/test/consensus.9.2.fa000066400000000000000000000002701467060157400170770ustar00rootroot00000000000000>14:43263973-43263995 GAGGGTGAGCAGAAGCAGGGTGG >14:43308392-43308414 CCTTTCTTTCCTGCTCTGAAGCT >14:43442685-43442707 CCCGTCTTCTTCGTTGCTCAGGC >14:43616643-43616665 GAGTGGGAGCTGAAGAAGTAGAT bcftools-1.21/test/consensus.9.2.out000066400000000000000000000002731467060157400173230ustar00rootroot00000000000000>14:43263973-43263995 GAGGGTGAGCAGAAGCAGGGTGG >14:43308392-43308414 CCTTTCTTTCCTGCTCTGAAGCT >14:43442685-43442707 CCCGTCTTCTTCGTTGCTCAGGC >14:43616643-43616665 GAGTGGGAGCTGAAGAAGAAGTAGAT bcftools-1.21/test/consensus.9.vcf000066400000000000000000000007241467060157400171330ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00105 14 43615818 . C . . END=43618193 GT 0|0 14 43616653 . T TGAA . . . GT 0|1 bcftools-1.21/test/consensus.beyond.1.out000066400000000000000000000000221467060157400204220ustar00rootroot00000000000000>1:1-1 A >2:2-2 G bcftools-1.21/test/consensus.beyond.fa000066400000000000000000000000211467060157400200410ustar00rootroot00000000000000>1:1-1 A >2:2-2 Gbcftools-1.21/test/consensus.beyond.vcf000066400000000000000000000003211467060157400202340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 1 1 3 . A T 100 . . GT 0/1 bcftools-1.21/test/consensus.fa000066400000000000000000000020071467060157400165700ustar00rootroot00000000000000>1:2-501 TACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG CAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA >2 GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT GTCGGGACAGCCTTTTTATAAAATTTTTCTAAATAATGTTGAGGCTTTGATACGTCAAAG TTATATTTCAAATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGA TTTGCTGCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGT GTTACATGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTG ACTCCTCTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATT TCAGACACAGTTAATCCAGAC bcftools-1.21/test/consensus.overlaps.1.1.out000066400000000000000000000000211467060157400211330ustar00rootroot00000000000000>1 CGAC >2 CGATC bcftools-1.21/test/consensus.overlaps.1.2.out000066400000000000000000000000171467060157400211410ustar00rootroot00000000000000>1 CGC >2 CGTC bcftools-1.21/test/consensus.overlaps.1.3.out000066400000000000000000000000211467060157400211350ustar00rootroot00000000000000>1 NGAN >2 NGATN bcftools-1.21/test/consensus.overlaps.1.4.out000066400000000000000000000000171467060157400211430ustar00rootroot00000000000000>1 NGN >2 NGTN bcftools-1.21/test/consensus.overlaps.1.fa000066400000000000000000000000301467060157400205530ustar00rootroot00000000000000>1 CGGGACAC >2 CGGGACAC bcftools-1.21/test/consensus.overlaps.1.vcf000066400000000000000000000006011467060157400207470ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 2 . GGGAC G, 649.73 . . GT 1/1 1/1 1 6 . CA C, 536.73 . . GT 0/0 1/1 2 2 . GGGAC G, 649.73 . . GT 1/1 1/1 2 6 . CA C, 536.73 . . GT 0/0 1/1 2 7 . A AT, 649.73 . . GT 1/1 1/1 bcftools-1.21/test/consensus.tab000066400000000000000000000000371467060157400167510ustar00rootroot000000000000001 421 480 2 1 60 2 241 300 bcftools-1.21/test/consensus.vcf000066400000000000000000000014411467060157400167610ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##ALT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 5 . C a . PASS . GT 0/1 1 5 . C t . PASS . GT 0/1 1 7 . T a . PASS . GT . 1 10 . G a . PASS . GT 0/1 1 12 . GACA ga . PASS . GT 0/1 1 16 . T taaa . PASS . GT 1/1 1 19 . A c . PASS . GT 0/1 1 61 . C a . PASS . GT 0/1 2 61 . AGAG aa . PASS . GT 0/1 2 119 . AAA t . PASS . GT 0/1 2 179 . G gacgtacgt . PASS . GT 0/1 2 200 . A . PASS END=210 GT 1/0 2 481 . T c,a . PASS . GT 0/2 bcftools-1.21/test/consensus17.1.out000066400000000000000000000004041467060157400173170ustar00rootroot00000000000000>1 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN >2 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN >3 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAACCTACGTATCAACTAAAGTGGTTGTT C >4 CCCCTACCATATGTGACATATAAAAAAGAACNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NN bcftools-1.21/test/consensus18.1.out000066400000000000000000000010011467060157400173120ustar00rootroot00000000000000>1 TACCATATGTGACATATAAAAAAGAACATCACCTACGTATCAACTAAAGTGGTTGTTTGC CAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC TTTAAAAACAAAAAAAAAGAA bcftools-1.21/test/consensus19.1.out000066400000000000000000000002101467060157400173140ustar00rootroot00000000000000>chr19:1048895-1049005 GCCAGTACGGGATCCCTGAACCATGGAATTTTCCTTTTCGGAGGAGCTACTGGTGCGGAC CTCGGCCCCCCAAGAGTCCAGCCCCTTGCCCCACCCCGCTGGACCCAAAGG bcftools-1.21/test/consensus2.1.out000066400000000000000000000004041467060157400172310ustar00rootroot00000000000000>1 CTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTA >2 CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTA >3 CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT A >4 CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TA bcftools-1.21/test/consensus2.2.out000066400000000000000000000004161467060157400172350ustar00rootroot00000000000000>1 CTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTCA A >2 CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC AA >3 CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT CAA >4 CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TCAA bcftools-1.21/test/consensus2.fa000066400000000000000000000004041467060157400166510ustar00rootroot00000000000000>1 CTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >2 CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >3 CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT C >4 CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TC bcftools-1.21/test/consensus2.vcf000066400000000000000000000011721467060157400170440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##INFO= ##ALT= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 59 . C a,Caa . PASS . GT 1|2 2 60 . C a,Caa . PASS . GT 1|2 3 61 . C a,Caa . PASS . GT 1|2 4 62 . C a,Caa . PASS . GT 1|2 bcftools-1.21/test/consensus20.1.out000066400000000000000000000000161467060157400173100ustar00rootroot00000000000000>ref AACCCCGT bcftools-1.21/test/consensus20.2.out000066400000000000000000000000161467060157400173110ustar00rootroot00000000000000>ref ACGYCCGT bcftools-1.21/test/consensus20.3.out000066400000000000000000000000161467060157400173120ustar00rootroot00000000000000>ref ACGYCCGT bcftools-1.21/test/consensus20.4.out000066400000000000000000000000161467060157400173130ustar00rootroot00000000000000>ref A.GTCCGT bcftools-1.21/test/consensus21.1.out000066400000000000000000000000471467060157400173150ustar00rootroot00000000000000>17 ACGTACGT >18 ACGTACGT >19 ACGYCCGT bcftools-1.21/test/consensus22.1.out000066400000000000000000000001321467060157400173110ustar00rootroot00000000000000>1:11-19 AAGTACGT >2:11-19 AAGTACGT >3:11-19 AAGTACGT >4:11-19 AAGTACGT >5:11-19 AAGTACGT bcftools-1.21/test/consensus22.2.out000066400000000000000000000001321467060157400173120ustar00rootroot00000000000000>1:11-19 .AGTACGT >2:11-19 TAGTACGT >3:11-19 AAGTACGT >4:11-19 .AGTACGT >5:11-19 .AGTACGT bcftools-1.21/test/consensus22.3.out000066400000000000000000000001271467060157400173170ustar00rootroot00000000000000>1:11-19 AGTACGT >2:11-19 TAGTACGT >3:11-19 AAGTACGT >4:11-19 AGTACGT >5:11-19 AGTACGT bcftools-1.21/test/consensus3.2.out000066400000000000000000000004171467060157400172370ustar00rootroot00000000000000>xx_1 ??ACCATATGTTCATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >xx_2 CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >xx_3 CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT C >xx_4 CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TC bcftools-1.21/test/consensus3.out000066400000000000000000000004031467060157400170720ustar00rootroot00000000000000>1 ??ACCATATGTTCATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >2 CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >3 CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT C >4 CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TC bcftools-1.21/test/consensus3.vcf000066400000000000000000000011511467060157400170420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##INFO= ##ALT= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 1 . C . . PASS . GT . 1 2 . T G . PASS . GT . 1 10 . GTGA G . PASS . GT 0|1 1 13 . A ATT . PASS . GT 0|1 bcftools-1.21/test/consensus4.out000066400000000000000000000004101467060157400170710ustar00rootroot00000000000000>1 TAAATACCGGGTGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TC >2 CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC >3 CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT C >4 CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT TC bcftools-1.21/test/consensus4.vcf000066400000000000000000000010721467060157400170450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##INFO= ##ALT= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T . . . 1 1 . C CAAA . . . 1 5 . CATA C . . . 1 8 . A AGGG . . . bcftools-1.21/test/consensus5.fa000066400000000000000000000000411467060157400166510ustar00rootroot00000000000000>4:86698932-86698942 GTGAATGAATG bcftools-1.21/test/consensus5.out000066400000000000000000000000451467060157400170760ustar00rootroot00000000000000>4:86698932-86698942 GTGAATGAATGAATG bcftools-1.21/test/consensus5.vcf000066400000000000000000000006471467060157400170550ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00119 4 86698932 rs34791496 G GTGAA 100 PASS . GT 0|1 4 86698932 rs538589807;rs569662225 GTGAA GTGAATGAA,G 100 PASS . GT 0|1 bcftools-1.21/test/consensus6.fa000066400000000000000000000003511467060157400166560ustar00rootroot00000000000000>NW_019171628.1:64330-64531 GAGAAAGAGAGAGAGAGCATGCTTCCAAACCCTTTGTTCTTTTTCTTCTGAAGAGAAGGT GACCTGGTTTTGAAACACTGGCTACAGCAAATCACTCAGAACACACACACACACAACACA CACACACACACACACACACACACACACACTCTCAGAACACACACACACACACGCACTTAC ATTTAGCCTTGGTGTTACTAT bcftools-1.21/test/consensus6.out000066400000000000000000000003421467060157400170770ustar00rootroot00000000000000>NW_019171628.1:64330-64531 GAGAAAGAGAGAGAGAGAGCATGCTTCCAAACCCTTTGTTCTTTTTCTTCTGAAGAGAAG GTGACCTGGTTTTGAAACACTGGCTACAGCAAATCACTCAGAACACACACACACACACAC ACACACACACACACACACACACTCTCAGAACACACACACACACACGCACTTACATTTAGC CTTGGTGTTACTAT bcftools-1.21/test/consensus6.vcf000066400000000000000000000005321467060157400170470ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=consensus6.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample NW_019171628.1 64334 . A AAG 159 . . GT 1/1 NW_019171628.1 64435 . CACACACACA C 170 . . GT 1/1 NW_019171628.1 64443 . C CACTCAG 72 . . GT 1/1 bcftools-1.21/test/consensus7.fa000066400000000000000000000000441467060157400166560ustar00rootroot00000000000000>1 ACGTACGTACGTACGTACGTACGTACGTACGT bcftools-1.21/test/consensus7.vcf000066400000000000000000000006551467060157400170560ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##ALT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 2 . C A . . . GT 0|1|0|1 1 3 . G A . . . GT 0|1|0|1 1 4 . T A . . . GT 0|1|0|1 1 6 . C A . . . GT 0/1/0/1 1 7 . G A . . . GT 0/1/0/1 1 8 . T A . . . GT 0/1/0/1 bcftools-1.21/test/consensus7a.out000066400000000000000000000000441467060157400172400ustar00rootroot00000000000000>1 AAAAAAAAACGTACGTACGTACGTACGTACGT bcftools-1.21/test/consensus7b.out000066400000000000000000000000441467060157400172410ustar00rootroot00000000000000>1 AAAAAMRWACGTACGTACGTACGTACGTACGT bcftools-1.21/test/consensus7c.out000066400000000000000000000000441467060157400172420ustar00rootroot00000000000000>1 ACGTACGTACGTACGTACGTACGTACGTACGT bcftools-1.21/test/consensus7d.out000066400000000000000000000000441467060157400172430ustar00rootroot00000000000000>1 ACGTAMRWACGTACGTACGTACGTACGTACGT bcftools-1.21/test/consensus8.vcf000066400000000000000000000016651467060157400170610ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##INFO= ##ALT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 1 5 . C a . PASS . GT 0/1 1 5 . C t . PASS . GT 0/1 1 7 . T a . PASS . GT . 1 10 . G a . PASS . GT 0/1 1 12 . GACA ga . PASS . GT 0/1 1 16 . T taaa . PASS . GT 1/1 1 19 . A c . PASS . GT 0/1 1 61 . C a . PASS . GT 0/1 2 61 . AGAG aa . PASS . GT 0/1 2 119 . AAA t . PASS . GT 0/1 2 179 . G gacgtacgt . PASS . GT 0/1 2 200 . A . PASS END=210 GT 1/0 2 300 . A . . PASS END=310;MinDP=10 GT 0/1 2 320 . A <*> . PASS END=330;MinDP=20 GT 0/1 2 481 . T c,a . PASS . GT 0/2 bcftools-1.21/test/contrast.1.1.out000066400000000000000000000010731467060157400171260ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##FORMAT= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2 280 . T A 246 . . GT 0/0 0/0 2 280 . T A 246 . NOVELAL=B GT 0/0 0/1 2 280 . T A 246 . NOVELAL=B GT 0/0 1/1 bcftools-1.21/test/contrast.1.2.out000066400000000000000000000006411467060157400171270ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2 280 . T A 246 . . GT 0/0 0/0 2 280 . T A 246 . NOVELGT=B GT 0/0 0/1 2 280 . T A 246 . NOVELGT=B GT 0/0 1/1 bcftools-1.21/test/contrast.1.out000066400000000000000000000007731467060157400167750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b c 1 100 . A G . . NASSOC=6,0,0,0 GT 0/0 0/0 0/0 1 101 . A G . . NASSOC=5,1,0,0 GT 0/0 0/0 0/1 1 102 . A G . . NASSOC=3,3,0,0 GT 0/0 0/1 1/1 1 103 . A G . . NASSOC=1,5,0,0 GT 1/1 1/1 0/1 bcftools-1.21/test/contrast.1.vcf000066400000000000000000000004011467060157400167300ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2 280 . T A 246 . . GT 0/0 0/0 2 280 . T A 246 . . GT 0/0 0/1 2 280 . T A 246 . . GT 0/0 1/1 bcftools-1.21/test/contrast.out000066400000000000000000000016571467060157400166400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b c 1 100 . A G . . PASSOC=1;FASSOC=0,0 GT 0/0 0/0 0/0 1 101 . A G . . PASSOC=0.333333;FASSOC=0,0.5;NOVELAL=c GT 0/0 0/0 0/1 1 102 . A G . . PASSOC=0.4;FASSOC=0.25,1;NOVELGT=c GT 0/0 0/1 1/1 1 103 . A G . . PASSOC=0.333333;FASSOC=1,0.5;NOVELAL=c GT 1/1 1/1 0/1 bcftools-1.21/test/contrast.vcf000066400000000000000000000004321467060157400165750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b c 1 100 . A G . . . GT 0/0 0/0 0/0 1 101 . A G . . . GT 0/0 0/0 0/1 1 102 . A G . . . GT 0/0 0/1 1/1 1 103 . A G . . . GT 1/1 1/1 0/1 bcftools-1.21/test/contrast0.txt000066400000000000000000000000041467060157400167110ustar00rootroot00000000000000a b bcftools-1.21/test/contrast1.txt000066400000000000000000000000021467060157400167100ustar00rootroot00000000000000c bcftools-1.21/test/convert.23andme000066400000000000000000000006701467060157400170770ustar00rootroot00000000000000# rsid chromosome position genotype rs001 1 2 AA rs002 1 10 AG rs003 1 14 AG rs004 1 24 TC rs005 1 44 CG rs006 1 53 GG rs007 1 60 GG rs008 1 62 CC rs009 1 75 AA rs010 1 80 GG rs011 1 89 TT rs012 1 96 -- rs013 1 99 CC rs014 1 102 GG rs015 1 112 TT rs016 2 5 CC rs017 2 11 CT rs018 2 16 CC rs019 2 20 GG rs020 2 33 CT rs021 2 39 AA rs022 2 44 CC rs023 2 48 CC rs024 2 55 AA rs025 2 59 CT rs026 Y 12 T rs027 Y 20 C bcftools-1.21/test/convert.23andme.vcf000066400000000000000000000017731467060157400176610ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1 1 2 rs001 A . . . . GT 0/0 1 10 rs002 G A . . . GT 1/0 1 14 rs003 A G . . . GT 0/1 1 24 rs004 T C . . . GT 0/1 1 44 rs005 C G . . . GT 0/1 1 53 rs006 G . . . . GT 0/0 1 60 rs007 A G . . . GT 1/1 1 62 rs008 C . . . . GT 0/0 1 75 rs009 A . . . . GT 0/0 1 80 rs010 G . . . . GT 0/0 1 89 rs011 C T . . . GT 1/1 1 96 rs012 T . . . . GT ./. 1 99 rs013 C . . . . GT 0/0 1 102 rs014 T G . . . GT 1/1 1 112 rs015 T . . . . GT 0/0 2 5 rs016 C . . . . GT 0/0 2 11 rs017 T C . . . GT 1/0 2 16 rs018 C . . . . GT 0/0 2 20 rs019 G . . . . GT 0/0 2 33 rs020 T C . . . GT 1/0 2 39 rs021 A . . . . GT 0/0 2 44 rs022 C . . . . GT 0/0 2 48 rs023 C . . . . GT 0/0 2 55 rs024 C A . . . GT 1/1 2 59 rs025 C T . . . GT 0/1 Y 12 rs026 G T . . . GT 1 Y 20 rs027 C . . . . 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bcftools-1.21/test/convert.gs.pl.samples000066400000000000000000000003141467060157400203270ustar00rootroot00000000000000ID_1 ID_2 missing 0 0 0 NA00001 NA00001 0 NA00002 NA00002 0 NA00003 NA00003 0 NA00004 NA00004 0 NA00005 NA00005 0 NA00006 NA00006 0 NA00007 NA00007 0 NA00008 NA00008 0 NA00009 NA00009 0 NA00010 NA00010 0 bcftools-1.21/test/convert.gs.vcf000066400000000000000000000103611467060157400170320ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 NA00005 NA00006 NA00007 NA00008 NA00009 NA00010 X 2698560 id9 G A . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698630 id10 A G . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698758 id11 CAA C . . . GT:GP 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698769 id12 AAG A . . . GT:GP 0/1:0,1,0 1/1:0,0,1 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698789 id14 C G . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698822 id15 A C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698831 id16 G A . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698889 id17 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698923 id18 G A . . . GT:GP 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698953 id19 A AGG . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2698954 id20 G A . . . GT:GP 0/1:0,1,0 1/1:0,0,1 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 X 2699002 id21 C A . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:0.33,0.33,0.33 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699025 id22 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699091 id23 G A . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699187 id24 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699188 id25 G C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699189 id26 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699217 id27 C T . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699246 id28 C A . . . GT:GP 0/1:0,1,0 1/1:0,0,1 0/1:0,1,0 1/1:0,0,1 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 X 2699275 id29 T G . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 1/1:0,0,1 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699350 id30 A T . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699360 id31 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699450 id32 A C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699507 id33 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699555 id34 C A . . . GT:GP 0/0:1,0,0 1/1:0,0,1 1/1:0,0,1 0/0:1,0,0 1/1:0,0,1 1/1:0,0,1 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/1:0,1,0 X 2699645 id35 G T . . . GT:GP 0/0:1,0,0 1/1:0,0,1 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 X 2699676 id36 G A . . . GT:GP 0/0:1,0,0 0/0:1,0,0 1/1:0,0,1 0/0:1,0,0 1/1:0,0,1 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699728 id37 C T . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699775 id38 C A . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 X 2699898 id39 C CT . . . GT:GP 0/0:1,0,0 0/0:1,0,0 1/1:0,0,1 0/0:1,0,0 1/1:0,0,1 0/1:0,1,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 X 2699968 id40 A G . . . GT:GP 0/0:0.5,0,0.5 0/0:1,0,0 0/0:1,0,0 1/1:0,0,1 0/0:1,0,0 0/1:0,1,0 0/0:1,0,0 0/0:1,0,0 0/1:0,1,0 0/1:0,1,0 X 2699970 id41 T C . . . GT:GP 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 0/0:1,0,0 bcftools-1.21/test/convert.gt.noHead.ids.vcf000066400000000000000000000042641467060157400210130ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 NA00005 NA00006 NA00007 NA00008 NA00009 NA00010 X 2698560 id9 G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698630 id10 A G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698758 id11 CAA C . . . GT 0|0 0|1 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698769 id12 AAG A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698789 id14 C G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698822 id15 A C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698831 id16 G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698889 id17 T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698923 id18 G A . . . GT 1|0 0|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698953 id19 A AGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698954 id20 G A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|1 0|0 0|0 X 2699002 id21 C A . . . GT 0|0 0|0 .|. 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699025 id22 T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699091 id23 G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699187 id24 T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0/1 X 2699188 id25 G C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699189 id26 T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699217 id27 C T . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699246 id28 C A . . . GT 1|0 1|1 0|1 1|1 1|0 0|1 0|0 0|1 0|0 1|0 X 2699275 id29 T G . . . GT 0|0 0|0 1|0 0|0 0|1 1|1 1|0 0|0 0|0 0|1 X 2699350 id30 A T . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699360 id31 T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699450 id32 A C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699507 id33 T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699555 id34 C A . . . GT 0 1 1 0 1 1|1 1|0 0|1 0|0 0|1 X 2699645 id35 G T . . . GT 0 1 0 0 0 0|0 0|0 0|1 0|0 0|0 X 2699676 id36 G A . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 X 2699728 id37 C T . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699775 id38 C A . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699898 id39 C CT . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 X 2699968 id40 A G . . . GT . 0 0 1 0 0|1 0|0 0|0 0|1 1|0 X 2699970 id41 T C . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 bcftools-1.21/test/convert.gt.noHead.vcf000066400000000000000000000044641467060157400202370ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 NA00005 NA00006 NA00007 NA00008 NA00009 NA00010 X 2698560 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698630 . A G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698758 . CAA C . . . GT 0|0 0|1 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698769 . AAG A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698770 . AG A . . . GT 0|0 0|1 0|0 0|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698770 . AG AAGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698789 . C G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698822 . A C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698831 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698889 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698923 . G A . . . GT 1|0 0|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698953 . A AGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698954 . G A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|1 0|0 0|0 X 2699002 . C A . . . GT 0|0 0|0 .|. 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699025 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699091 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699187 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0/1 X 2699188 . G C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699189 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699217 . C T . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699246 . C A . . . GT 1|0 1|1 0|1 1|1 1|0 0|1 0|0 0|1 0|0 1|0 X 2699275 . T G . . . GT 0|0 0|0 1|0 0|0 0|1 1|1 1|0 0|0 0|0 0|1 X 2699350 . A T . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699360 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699450 . A C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699507 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699555 . C A . . . GT 0 1 1 0 1 1|1 1|0 0|1 0|0 0|1 X 2699645 . G T . . . GT 0 1 0 0 0 0|0 0|0 0|1 0|0 0|0 X 2699676 . G A . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 X 2699728 . C T . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699775 . C A . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699898 . C CT . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 X 2699968 . A G . . . GT . 0 0 1 0 0|1 0|0 0|0 0|1 1|0 X 2699970 . T C . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699990 . C . . END=2700054 GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 bcftools-1.21/test/convert.gt.vcf000066400000000000000000000051651467060157400170410ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##bcftools_normVersion=1.2+htslib-1.2.1 ##bcftools_normCommand=norm -m - convert.vcf ##bcftools_annotateVersion=1.2+htslib-1.2.1 ##bcftools_annotateCommand=annotate -x FORMAT,QUAL #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 NA00005 NA00006 NA00007 NA00008 NA00009 NA00010 X 2698560 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698630 . A G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698758 . CAA C . . . GT 0|0 0|1 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698769 . AAG A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698770 . AG A . . . GT 0|0 0|1 0|0 0|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698770 . AG AAGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698789 . C G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698822 . A C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698831 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698889 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698923 . G A . . . GT 1|0 0|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 X 2698953 . A AGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2698954 . G A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|1 0|0 0|0 X 2699002 . C A . . . GT 0|0 0|0 .|. 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699025 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699091 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699187 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0/1 X 2699188 . G C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699189 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699217 . C T . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699246 . C A . . . GT 1|0 1|1 0|1 1|1 1|0 0|1 0|0 0|1 0|0 1|0 X 2699275 . T G . . . GT 0|0 0|0 1|0 0|0 0|1 1|1 1|0 0|0 0|0 0|1 X 2699350 . A T . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699360 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699450 . A C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 X 2699507 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 X 2699555 . C A . . . GT 0 1 1 0 1 1|1 1|0 0|1 0|0 0|1 X 2699645 . G T . . . GT 0 1 0 0 0 0|0 0|0 0|1 0|0 0|0 X 2699676 . G A . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 X 2699728 . C T . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699775 . C A . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 X 2699898 . C CT . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 X 2699968 . A G . . . GT . 0 0 1 0 0|1 0|0 0|0 0|1 1|0 X 2699970 . T C . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 bcftools-1.21/test/convert.gvcf.out000066400000000000000000000700071467060157400174020ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##contig= ##SnvTheta=0.001 ##IndelTheta=0.0001 ##MaxDepth_1=114.18 ##MaxDepth_10=131.73 ##MaxDepth_11=117.27 ##MaxDepth_12=116.97 ##MaxDepth_13=102.24 ##MaxDepth_14=101.55 ##MaxDepth_15=95.22 ##MaxDepth_16=111.33 ##MaxDepth_17=112.59 ##MaxDepth_18=121.86 ##MaxDepth_19=111.12 ##MaxDepth_2=121.83 ##MaxDepth_20=111.24 ##MaxDepth_21=98.43 ##MaxDepth_22=76.23 ##MaxDepth_3=120.09 ##MaxDepth_4=124.50 ##MaxDepth_5=119.82 ##MaxDepth_6=122.22 ##MaxDepth_7=120.27 ##MaxDepth_8=120.45 ##MaxDepth_9=102.48 ##MaxDepth_M=7005.66 ##MaxDepth_X=61.05 ##MaxDepth_Y=37.17 ##FILTER= ##gvcftools_version="0.16" ##FILTER= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE99 22 1 . N . 0 LowGQX END=9;BLOCKAVG_min30p3a GT:GQX:DP:DPF .:.:0:0 22 10 . C . 0 LowGQX END=20;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:5:2:0 22 21 . C . 0 LowGQX END=26;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:10:4:0 22 27 . C . 0 LowGQX END=42;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:15:6:0 22 43 . G . 0 LowGQX END=50;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:21:8:0 22 51 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 22 52 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 22 53 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 22 54 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 22 55 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 22 56 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 57 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 58 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 59 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 60 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 61 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 62 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 63 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 64 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 65 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 66 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 67 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 68 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 69 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 70 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 71 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 72 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 22 73 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 74 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 75 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 76 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 77 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 78 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 79 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 80 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 81 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 82 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 83 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 84 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 85 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 22 86 . G C 23 PASS SNVSB=0;SNVHPOL=2 GT:GQ:GQX:DP:DPF:AD 0/1:56:23:22:0:16,6 22 87 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 88 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 89 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 90 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 91 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 92 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 93 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 94 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 95 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 96 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 97 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 98 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 99 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 100 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 101 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 22 102 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 103 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 104 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 105 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 106 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 107 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 108 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 109 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 110 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 111 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 112 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 113 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 114 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 115 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 116 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 117 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 118 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 119 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 120 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 121 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 122 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 123 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 124 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 125 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 126 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 127 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 128 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 129 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 130 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 131 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 132 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 133 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 134 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 135 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 136 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 137 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 138 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 139 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 140 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 22 141 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 142 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 143 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 144 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 145 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 146 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 147 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 148 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 149 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 150 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 151 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 152 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 153 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 154 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 155 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 156 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 157 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 158 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 159 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 160 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 161 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 162 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 163 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 164 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 165 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 166 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 167 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 168 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 169 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 170 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 171 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 172 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 173 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 174 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 175 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 176 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 177 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 178 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 179 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 180 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 181 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 182 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 183 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 184 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 185 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 22 186 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:93:32:2 22 187 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:93:32:2 22 188 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 189 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 190 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 191 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 192 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 193 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 194 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 195 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 196 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 197 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 198 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 199 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 200 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 201 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 202 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 203 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 204 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 22 205 . T . 0 PASS . GT:GQX:DP:DPF 0/0:72:36:0 22 206 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 207 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 208 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 209 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 210 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 211 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 212 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 213 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 214 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 215 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 216 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 217 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 218 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 219 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 220 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 221 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 222 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 223 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 224 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 225 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 226 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 227 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 228 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 229 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 230 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 231 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 232 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 233 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 234 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 235 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 236 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 237 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 238 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 239 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 240 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 241 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 242 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 243 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 244 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 245 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 246 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 247 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 248 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 249 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 22 250 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 251 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 252 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 253 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 254 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 255 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 256 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 257 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 22 258 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 259 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 260 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 261 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 262 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 263 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 264 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 265 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 266 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 267 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 268 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 269 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 22 270 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 271 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 272 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 273 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 274 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 275 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 276 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 277 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 278 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 279 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 22 280 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 281 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 282 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 283 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 284 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 285 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 286 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 287 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 288 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 289 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 290 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 291 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 292 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 293 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 294 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 295 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 296 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 297 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 298 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 299 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 300 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 301 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 302 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 303 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 304 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 305 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 306 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 307 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 308 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 309 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 310 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 311 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 312 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 313 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 314 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 22 315 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:220:74:0 22 316 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:220:74:0 22 317 . T . 0 HighDepth END=342;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:229:77:0 22 343 . T . 0 HighDepth END=377;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:241:81:0 22 378 . T . 0 HighDepth END=384;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:200:75:0 22 385 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 22 386 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 22 387 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 22 388 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 22 389 . C . 0 HighDepth END=390;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:223:75:0 22 391 . T . 0 PASS . GT:GQX:DP:DPF 0/0:223:75:1 22 392 . T . 0 HighDepth END=397;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:223:75:0 22 398 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 399 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 400 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 401 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 402 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 403 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 404 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 405 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 406 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 407 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 408 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 409 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 410 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 411 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 412 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 413 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 414 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 415 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 22 416 . 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GT:PL:GP 0:0,68:1,0 0:0,34:1,0 0:0,32:1,0 0:0,162:1,0 0:0,63:1,0 0|0:0,15,149:1,0,0 0|0:0,21,181:1,0,0 0|0:0,45,255:1,0,0 0|0:0,27,207:1,0,0 0|0:0,24,196:1,0,0 bcftools-1.21/test/create-bam-test000077500000000000000000000076421467060157400171550ustar00rootroot00000000000000#!/usr/bin/env perl # # Author: petr.danecek@sanger # use strict; use warnings; use Carp; my $opts = parse_params(); create_test($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "Usage: create-bam-test [OPTIONS]\n", "Options:\n", " -b, --bam FILE \n", " -f, --fa-ref FILE \n", " -k, --keep-samples \n", " -o, --output-prefix PATH \n", " -O, --offset INT \n", " -r, --region REGION \n", " -h, -?, --help This help message.\n", "\n"; exit -1; } sub parse_params { my $opts = {}; if ( -t STDIN && !@ARGV ) { error(); } while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '-b' || $arg eq '--bam' ) { $$opts{bam}=shift(@ARGV); next } if ( $arg eq '-f' || $arg eq '--fa-ref' ) { $$opts{ref}=shift(@ARGV); next } if ( $arg eq '-k' || $arg eq '--keep-samples' ) { $$opts{keep_samples}=1; next } if ( $arg eq '-o' || $arg eq '--output-prefix' ) { $$opts{out}=shift(@ARGV); next } if ( $arg eq '-O' || $arg eq '--offset' ) { $$opts{offset}=shift(@ARGV); next } if ( $arg eq '-r' || $arg eq '--region' ) { $$opts{region}=shift(@ARGV); next } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } if ( !exists($$opts{bam}) ) { error("Missing the -b option.\n") } if ( !exists($$opts{ref}) ) { error("Missing the -f option.\n") } if ( !exists($$opts{out}) ) { error("Missing the -o option.\n") } if ( !exists($$opts{region}) ) { error("Missing the -r option.\n") } return $opts; } sub create_test { my ($opts) = @_; if ( !($$opts{region}=~/^([^:]+):(\d+)-(\d+)$/) ) { error("Could not parse the region: $$opts{region}"); } my %readnames = (); my $chr = $1; my $beg = $2; my $end = $3; my $ori_beg = $beg; my $ori_end = $end; my @reads = (); my $cmd = "samtools view -h $$opts{bam} $$opts{region}"; open(my $out,'>',"$$opts{out}.sam") or error("$$opts{out}.sam: $!"); open(my $fh,"$cmd |") or error("$cmd: $!"); while (my $line=<$fh>) { my @vals = split(/\t/,$line); if ( $vals[0] eq '@HD' ) { print $out $line; next; } if ( $$opts{keep_samples} && $vals[0] eq '@RG' ) { print $out $line; next; } if ( $vals[0] =~ /^\@/ ) { next; } if ( $vals[3] < $beg ) { $beg = $vals[3]; } if ( $vals[3] + length($vals[9]) > $end ) { $end = $vals[3] + length($vals[9]); } my $mate_mapped = 1; if ( $vals[6] ne $chr && $vals[6] ne '=' ) { $vals[6] = '='; $mate_mapped = 0; } if ( $vals[7] < $beg or $vals[7] > $end ) { $mate_mapped = 0; } if ( !$mate_mapped ) { $vals[1] &= ~0x8; $vals[6] = '*'; $vals[7] = $vals[3]; } chomp($vals[-1]); if ( !$$opts{keep_samples} ) { my $i; for ($i=0; $i<@vals; $i++) { if ($vals[$i]=~/^RG:Z:/) { last; } } if ( $i!=@vals ) { splice(@vals,$i,1); } push @vals,"RG:Z:rg"; } push @reads, \@vals; } close($fh) or error("close failed: $cmd"); print $out "\@SQ\tSN:$chr\tLN:".($end-$beg+1)."\n"; if ( !$$opts{keep_samples} ) { print $out "\@RG\tID:rg\tSM:sample\n"; } if ( exists($$opts{offset}) ) { $beg = abs($$opts{offset}) + 1; } for my $read (@reads) { $$read[3] -= $beg - 1; $$read[7] -= $beg - 1; print $out join("\t",@$read)."\n"; } close($out) or error("close failed: $$opts{out}.sam"); `samtools view -b $$opts{out}.sam -o $$opts{out}.bam`; `samtools index $$opts{out}.bam`; `samtools faidx $$opts{ref} $chr:$beg-$end | sed 's,:, ,' > $$opts{out}.fa`; `samtools faidx $$opts{out}.fa`; print "offset\t-".($beg-1)."\n"; } bcftools-1.21/test/csq.1.out000066400000000000000000000106531467060157400157240ustar00rootroot0000000000000090 C T 5_prime_utr|XYZ|ENST00000000001|protein_coding 90 C T 5_prime_utr|XYZ|ENST00000000001|protein_coding 102 C T synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T 102 C T synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T 103 G A missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A 103 G A missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A 103 G C missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C 103 G C missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C 107 G A missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A 107 G A missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A 108 T A @107,splice_region|XYZ|ENST00000000001|protein_coding 108 T A @107,splice_region|XYZ|ENST00000000001|protein_coding 121 ACG A inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding 121 ACG A inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding 124 TA T @121 124 TA T @121 128 T C missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding 128 T C missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding 129 A C @128,splice_region|XYZ|ENST00000000001|protein_coding 129 A C @128,splice_region|XYZ|ENST00000000001|protein_coding 140 TA AACG inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding 140 TA AACG inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding 142 C CC @140,splice_region|XYZ|ENST00000000001|protein_coding 142 C CC @140,splice_region|XYZ|ENST00000000001|protein_coding 145 AC TA stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA 145 AC TA stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA 160 TA T *frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding 160 TA T *frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding 190 C T 3_prime_utr|XYZ|ENST00000000001|protein_coding 190 C T 3_prime_utr|XYZ|ENST00000000001|protein_coding 97 A C 3_prime_utr|ABC|ENST00000000002|protein_coding 97 A C 3_prime_utr|ABC|ENST00000000002|protein_coding 105 AC A @121 105 AC A @121 121 AC A frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A,splice_region|ABC|ENST00000000002|protein_coding 121 AC A splice_region|ABC|ENST00000000002|protein_coding,stop_gained&frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A 126 C CTT @127 126 C CTT @127 127 G GG inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG 127 G GG inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG 144 TAC T @148 144 TAC T @148 148 TA T inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding 148 TA T inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding 164 T G missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G 164 T G missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G 165 A C synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C 165 A C synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C 169 A G @170 169 A G @170 170 C T missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T 170 C T missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T 199 G T 5_prime_utr|ABC|ENST00000000002|protein_coding 199 G T 5_prime_utr|ABC|ENST00000000002|protein_coding 20 T A non_coding|mir-007||lincRNA 20 T A non_coding|mir-007||lincRNA 109 ACGTACGT A splice_acceptor|QWRTY|ENST00000000003|protein_coding 109 ACGTACGT A splice_acceptor|QWRTY|ENST00000000003|protein_coding 113 A T splice_region|QWRTY|ENST00000000003|protein_coding 113 A T splice_region|QWRTY|ENST00000000003|protein_coding 120 T A intron|QWRTY||protein_coding 120 T A intron|QWRTY||protein_coding 152 T A splice_region|QWRTY|ENST00000000003|protein_coding 152 T A splice_region|QWRTY|ENST00000000003|protein_coding 159 G A splice_donor|QWRTY|ENST00000000003|protein_coding 159 G A splice_donor|QWRTY|ENST00000000003|protein_coding bcftools-1.21/test/csq.2.gff000066400000000000000000000157151467060157400156640ustar00rootroot00000000000000##gff-version 3 #! This file shows which fields are used and required by `bcftools +csq`. It is a trimmed version #! of the GFF3 format, see an example of the full format here #! ftp://ftp.ensembl.org/pub/grch37/release-84/gff3/homo_sapiens/ #! ### 1 . gene 90 110 . + . ID=gene:ENSG001;Name=XYZ;biotype=protein_coding 1 . transcript 99 110 . + . ID=transcript:ENST001;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST001 1 . transcript 99 110 . + . ID=transcript:ENST002;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST002 1 . transcript 99 110 . + . ID=transcript:ENST003;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST003 1 . transcript 99 110 . + . ID=transcript:ENST004;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST004 1 . transcript 99 110 . + . ID=transcript:ENST005;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST005 1 . transcript 99 110 . + . ID=transcript:ENST006;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST006 1 . transcript 99 110 . + . ID=transcript:ENST007;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST007 1 . transcript 99 110 . + . ID=transcript:ENST008;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST008 1 . transcript 99 110 . + . ID=transcript:ENST009;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST009 1 . transcript 99 110 . + . ID=transcript:ENST010;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST010 1 . transcript 99 110 . + . ID=transcript:ENST011;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST011 1 . transcript 99 110 . + . ID=transcript:ENST012;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST012 1 . transcript 99 110 . + . ID=transcript:ENST013;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST013 1 . transcript 99 110 . + . ID=transcript:ENST014;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST014 1 . transcript 99 110 . + . ID=transcript:ENST015;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST015 1 . transcript 99 110 . + . ID=transcript:ENST016;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST016 1 . transcript 99 110 . + . ID=transcript:ENST017;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST017 1 . transcript 99 110 . + . ID=transcript:ENST018;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST018 1 . transcript 99 110 . + . ID=transcript:ENST019;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST019 1 . transcript 99 110 . + . ID=transcript:ENST020;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST020 1 . transcript 99 110 . + . ID=transcript:ENST021;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST021 1 . transcript 99 110 . + . ID=transcript:ENST022;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST022 1 . transcript 99 110 . + . ID=transcript:ENST023;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST023 1 . transcript 99 110 . + . ID=transcript:ENST024;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST024 1 . transcript 99 110 . + . ID=transcript:ENST025;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST025 1 . transcript 99 110 . + . ID=transcript:ENST026;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST026 1 . transcript 99 110 . + . ID=transcript:ENST027;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST027 1 . transcript 99 110 . + . ID=transcript:ENST028;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST028 1 . transcript 99 110 . + . ID=transcript:ENST029;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST029 1 . transcript 99 110 . + . ID=transcript:ENST030;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST030 1 . transcript 99 110 . + . ID=transcript:ENST031;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST031 1 . transcript 99 110 . + . ID=transcript:ENST032;Parent=gene:ENSG001;biotype=protein_coding 1 . CDS 99 110 . + 1 Parent=transcript:ENST032 2 . gene 90 110 . + . ID=gene:ENSG101;Name=XYZ;biotype=protein_coding 2 . transcript 99 110 . + . ID=transcript:ENST101;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST101 2 . transcript 99 110 . + . ID=transcript:ENST102;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST102 2 . transcript 99 110 . + . ID=transcript:ENST103;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST103 2 . transcript 99 110 . + . ID=transcript:ENST104;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST104 2 . transcript 99 110 . + . ID=transcript:ENST105;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST105 2 . transcript 99 110 . + . ID=transcript:ENST106;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST106 2 . transcript 99 110 . + . ID=transcript:ENST107;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST107 2 . transcript 99 110 . + . ID=transcript:ENST108;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST108 2 . transcript 99 110 . + . ID=transcript:ENST109;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST109 2 . transcript 99 110 . + . ID=transcript:ENST110;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST110 2 . transcript 99 110 . + . ID=transcript:ENST111;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST111 2 . transcript 99 110 . + . ID=transcript:ENST112;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST112 2 . transcript 99 110 . + . ID=transcript:ENST113;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST113 2 . transcript 99 110 . + . ID=transcript:ENST114;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST114 2 . transcript 99 110 . + . ID=transcript:ENST115;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST115 2 . transcript 99 110 . + . ID=transcript:ENST116;Parent=gene:ENSG101;biotype=protein_coding 2 . CDS 99 110 . + 1 Parent=transcript:ENST116 bcftools-1.21/test/csq.2.out000066400000000000000000000057641467060157400157340ustar00rootroot00000000000000missense|XYZ|ENST001|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST001|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST019|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST019|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST020|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST020|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST021|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST021|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST022|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST022|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST023|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST023|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST024|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST024|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST025|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST025|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST026|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST026|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST027|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST027|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST028|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST028|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST029|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST029|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST030|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST030|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST031|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST031|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST032|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST032|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST101|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST101|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST103|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST103|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST104|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST104|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST105|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST105|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST106|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST106|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST107|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST107|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST108|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST108|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST109|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST109|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST110|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST110|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST111|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST111|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST112|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST112|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST113|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST113|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST114|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST114|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST115|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST115|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST116|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST116|protein_coding|+|2V>2I|103G>A bcftools-1.21/test/csq.2.vcf000066400000000000000000000004541467060157400156720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl 2 103 . G A 1 . . GT 1|1 1 103 . G A 1 . . GT 1|1 bcftools-1.21/test/csq.3.out000066400000000000000000000114401467060157400157210ustar00rootroot00000000000000missense|XYZ|ENST001|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST001|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST002|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST002|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST003|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST003|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST004|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST004|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST005|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST005|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST006|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST006|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST007|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST007|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST008|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST008|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST009|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST009|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST010|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST010|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST011|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST011|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST012|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST012|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST013|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST013|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST014|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST014|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST015|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST015|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST016|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST016|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST017|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST017|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST018|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST018|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST019|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST019|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST020|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST020|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST021|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST021|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST022|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST022|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST023|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST023|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST024|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST024|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST025|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST025|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST026|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST026|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST027|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST027|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST028|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST028|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST029|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST029|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST030|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST030|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST031|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST031|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST032|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST032|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST101|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST101|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST102|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST102|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST103|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST103|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST104|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST104|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST105|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST105|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST106|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST106|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST107|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST107|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST108|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST108|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST109|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST109|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST110|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST110|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST111|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST111|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST112|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST112|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST113|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST113|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST114|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST114|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST115|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST115|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST116|protein_coding|+|2V>2I|103G>A missense|XYZ|ENST116|protein_coding|+|2V>2I|103G>A bcftools-1.21/test/csq.chr.gff3000066400000000000000000000051071467060157400163540ustar00rootroot00000000000000##gff-version 3 #! This file shows which fields are used and required by `bcftools +csq`. It is a trimmed version #! of the GFF3 format, see an example of the full format here #! ftp://ftp.ensembl.org/pub/grch37/release-84/gff3/homo_sapiens/ #! ### chr1 . gene 90 200 . + . ID=gene:ENSG00000000001;Name=XYZ;biotype=protein_coding chr1 . transcript 90 200 . + . ID=transcript:ENST00000000001;Parent=gene:ENSG00000000001;biotype=protein_coding chr1 . exon 90 110 . + . Parent=transcript:ENST00000000001 chr1 . five_prime_UTR 90 98 . + . Parent=transcript:ENST00000000001 chr1 . CDS 99 110 . + 1 Parent=transcript:ENST00000000001 chr1 . exon 120 130 . + . Parent=transcript:ENST00000000001 chr1 . CDS 120 130 . + 1 Parent=transcript:ENST00000000001 chr1 . exon 140 150 . + . Parent=transcript:ENST00000000001 chr1 . CDS 140 150 . + 2 Parent=transcript:ENST00000000001 chr1 . exon 160 200 . + . Parent=transcript:ENST00000000001 chr1 . CDS 160 171 . + 0 Parent=transcript:ENST00000000001 chr1 . three_prime_UTR 172 200 . + . Parent=transcript:ENST00000000001 chr2 . gene 80 200 . - . ID=gene:ENSG00000000002;Name=ABC;biotype=protein_coding chr2 . transcript 80 200 . - . ID=transcript:ENST00000000002;Parent=gene:ENSG00000000002;biotype=protein_coding chr2 . exon 80 110 . - . Parent=transcript:ENST00000000002 chr2 . three_prime_UTR 80 98 . - . Parent=transcript:ENST00000000002 chr2 . CDS 99 110 . - 0 Parent=transcript:ENST00000000002 chr2 . exon 120 130 . - . Parent=transcript:ENST00000000002 chr2 . CDS 120 130 . - 2 Parent=transcript:ENST00000000002 chr2 . exon 140 150 . - . Parent=transcript:ENST00000000002 chr2 . CDS 140 150 . - 1 Parent=transcript:ENST00000000002 chr2 . exon 160 200 . - . Parent=transcript:ENST00000000002 chr2 . CDS 160 171 . - 1 Parent=transcript:ENST00000000002 chr2 . five_prime_UTR 172 200 . - . Parent=transcript:ENST00000000002 chr3 . lincRNA_gene 20 50 . - . ID=gene:ENSG00000000004;Name=mir-007;biotype=lincRNA chr3 . lincRNA 20 50 . - . ID=transcript:ENSG00000000004;Parent=gene:ENSG00000000004;biotype=lincRNA chr3 . gene 100 200 . - . ID=gene:ENSG00000000003;Name=QWRTY;biotype=protein_coding chr3 . transcript 100 200 . - . ID=transcript:ENST00000000003;Parent=gene:ENSG00000000003;biotype=protein_coding chr3 . exon 100 110 . - . Parent=transcript:ENST00000000003 chr3 . three_prime_UTR 100 105 . - . Parent=transcript:ENST00000000003 chr3 . CDS 106 110 . - 0 Parent=transcript:ENST00000000003 chr3 . exon 160 200 . - . Parent=transcript:ENST00000000003 chr3 . CDS 160 171 . - 0 Parent=transcript:ENST00000000003 chr3 . five_prime_UTR 172 200 . - . Parent=transcript:ENST00000000003 bcftools-1.21/test/csq.chr.out000066400000000000000000000000611467060157400163300ustar00rootroot00000000000000. missense|gtrV|gtrV|protein_coding|+|1L>1I|1T>A bcftools-1.21/test/csq.fa000066400000000000000000000034601467060157400153420ustar00rootroot00000000000000>1 ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT >2 ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT >3 ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT bcftools-1.21/test/csq.gff3000066400000000000000000000047411467060157400156040ustar00rootroot00000000000000##gff-version 3 #! This file shows which fields are used and required by `bcftools +csq`. It is a trimmed version #! of the GFF3 format, see an example of the full format here #! ftp://ftp.ensembl.org/pub/grch37/release-84/gff3/homo_sapiens/ #! ### 1 . gene 90 200 . + . ID=gene:ENSG00000000001;Name=XYZ;biotype=protein_coding 1 . transcript 90 200 . + . ID=transcript:ENST00000000001;Parent=gene:ENSG00000000001;biotype=protein_coding 1 . exon 90 110 . + . Parent=transcript:ENST00000000001 1 . five_prime_UTR 90 98 . + . Parent=transcript:ENST00000000001 1 . CDS 99 110 . + 1 Parent=transcript:ENST00000000001 1 . exon 120 130 . + . Parent=transcript:ENST00000000001 1 . CDS 120 130 . + 1 Parent=transcript:ENST00000000001 1 . exon 140 150 . + . Parent=transcript:ENST00000000001 1 . CDS 140 150 . + 2 Parent=transcript:ENST00000000001 1 . exon 160 200 . + . Parent=transcript:ENST00000000001 1 . CDS 160 171 . + 0 Parent=transcript:ENST00000000001 1 . three_prime_UTR 172 200 . + . Parent=transcript:ENST00000000001 2 . gene 80 200 . - . ID=gene:ENSG00000000002;Name=ABC;biotype=protein_coding 2 . transcript 80 200 . - . ID=transcript:ENST00000000002;Parent=gene:ENSG00000000002;biotype=protein_coding 2 . exon 80 110 . - . Parent=transcript:ENST00000000002 2 . three_prime_UTR 80 98 . - . Parent=transcript:ENST00000000002 2 . CDS 99 110 . - 0 Parent=transcript:ENST00000000002 2 . exon 120 130 . - . Parent=transcript:ENST00000000002 2 . CDS 120 130 . - 2 Parent=transcript:ENST00000000002 2 . exon 140 150 . - . Parent=transcript:ENST00000000002 2 . CDS 140 150 . - 1 Parent=transcript:ENST00000000002 2 . exon 160 200 . - . Parent=transcript:ENST00000000002 2 . CDS 160 171 . - 1 Parent=transcript:ENST00000000002 2 . five_prime_UTR 172 200 . - . Parent=transcript:ENST00000000002 3 . lincRNA_gene 20 50 . - . ID=gene:ENSG00000000004;Name=mir-007;biotype=lincRNA 3 . lincRNA 20 50 . - . ID=transcript:ENSG00000000004;Parent=gene:ENSG00000000004;biotype=lincRNA 3 . gene 100 200 . - . ID=gene:ENSG00000000003;Name=QWRTY;biotype=protein_coding 3 . transcript 100 200 . - . ID=transcript:ENST00000000003;Parent=gene:ENSG00000000003;biotype=protein_coding 3 . exon 100 110 . - . Parent=transcript:ENST00000000003 3 . three_prime_UTR 100 105 . - . Parent=transcript:ENST00000000003 3 . CDS 106 110 . - 0 Parent=transcript:ENST00000000003 3 . exon 160 200 . - . Parent=transcript:ENST00000000003 3 . CDS 160 171 . - 0 Parent=transcript:ENST00000000003 3 . five_prime_UTR 172 200 . - . Parent=transcript:ENST00000000003 bcftools-1.21/test/csq.nchr.fa000066400000000000000000000001001467060157400162570ustar00rootroot00000000000000>1 TTAAGGCTGTTTTTTTATTAATGTCATCGTCCATCCTGCAGGGTTGAACTTGAAAGAATA bcftools-1.21/test/csq.nchr.gff000066400000000000000000000003131467060157400164410ustar00rootroot000000000000001 . gene 1 60 . + . ID=gene:gtrV;Name=gtrV;gene_biotype=protein_coding 1 . transcript 1 60 . + . ID=transcript:gtrV;Parent=gene:gtrV;gene_biotype=protein_coding 1 . CDS 1 60 . + . Parent=transcript:gtrV bcftools-1.21/test/csq.nchr.vcf000066400000000000000000000003151467060157400164570ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=dummy.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl 1 1 . T A . . . GT 0|1 bcftools-1.21/test/csq.vcf000066400000000000000000000064451467060157400155400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SmplAAA SmplBBB 1 90 . C T . . EXP=5_prime_utr|XYZ|ENST00000000001|protein_coding GT 1|0 1|1 1 102 . C T 1 . EXP=synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T GT 1|0 1|0 1 103 . G A 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A GT 1|0 0|0 1 103 . G C 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C GT 0|0 1|0 1 107 . G A 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A GT 1|0 1|0 1 108 . T A 1 . EXP=splice_region|XYZ|ENST00000000001|protein_coding,@107 GT 1|0 1|0 1 121 . ACG A . . EXP=inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 1|0 1 124 . TA T . . EXP=@121 GT 1|0 1|0 1 128 . T C 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0/0 1 129 . A C 1 . EXP=splice_region|XYZ|ENST00000000001|protein_coding,@128 GT 1|0 0/0 1 140 . TA AACG . . EXP=inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 1 142 . C CC . . EXP=splice_region|XYZ|ENST00000000001|protein_coding,@140 GT 1|0 0|0 1 145 . AC TA . . EXP=stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA GT 1|0 0|0 1 160 . TA T . . EXP=*frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 1 190 . C T . . EXP=3_prime_utr|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 2 97 . A C . . EXP=3_prime_utr|ABC|ENST00000000002|protein_coding GT 1|0 0|0 2 105 . AC A . . EXP=@121 GT 1|0 0|0 2 121 . AC A . . EXP=frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A,splice_region|ABC|ENST00000000002|protein_coding GT 1|0 0|0 2 126 . C CTT . . EXP=@127 GT 1|0 0|0 2 127 . G GG . . EXP=inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG GT 1|0 0|0 2 144 . TAC T . . EXP=@148 GT 1|0 0|0 2 148 . TA T . . EXP=inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding GT 1|0 0|0 2 164 . T G . . EXP=missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G GT 1|0 0|0 2 165 . A C . . EXP=synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C GT 1|0 0|0 2 169 . A G . . EXP=@170 GT 1|0 0|0 2 170 . C T . . EXP=missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T GT 1|0 0|0 2 199 . G T . . EXP=5_prime_utr|ABC|ENST00000000002|protein_coding GT 1|0 0|0 3 20 . T A . . EXP=non_coding|mir-007||lincRNA GT 1|0 0|0 3 109 . ACGTACGT A 1 . EXP=splice_acceptor|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 3 113 . A T . . EXP=splice_region|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 3 120 . T A . . EXP=intron|QWRTY||protein_coding GT 1|0 0|0 3 152 . T A . . EXP=splice_region|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 3 159 . G A . . EXP=splice_donor|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 bcftools-1.21/test/csq.ychr.fa000066400000000000000000000001031467060157400162750ustar00rootroot00000000000000>chr1 TTAAGGCTGTTTTTTTATTAATGTCATCGTCCATCCTGCAGGGTTGAACTTGAAAGAATA bcftools-1.21/test/csq.ychr.gff000066400000000000000000000003241467060157400164560ustar00rootroot00000000000000chr1 . gene 1 60 . + . ID=gene:gtrV;Name=gtrV;gene_biotype=protein_coding chr1 . transcript 1 60 . + . ID=transcript:gtrV;Parent=gene:gtrV;gene_biotype=protein_coding chr1 . CDS 1 60 . + . Parent=transcript:gtrV bcftools-1.21/test/csq.ychr.vcf000066400000000000000000000003231467060157400164710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=dummy.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl chr1 1 . T A . . . GT 0|1 bcftools-1.21/test/csq/000077500000000000000000000000001467060157400150275ustar00rootroot00000000000000bcftools-1.21/test/csq/EDUMMY0001/000077500000000000000000000000001467060157400163305ustar00rootroot00000000000000bcftools-1.21/test/csq/EDUMMY0001/EDUMMY0001.fa000066400000000000000000000024011467060157400201360ustar00rootroot00000000000000>chr1 TTAAGGCTGTTTTTTTATTAATGTCATCGTCCATCCTGCAGGGTTGAACTTGAAAGAATA CGATTCTCCTGGTGCTAAACTTTCAAATTTTTTAACTTGCTCTTTCCACCCGTAATCTGG GAGTGGGGTAAGATTGAAAAAATATAAACATGAGATTAACGATGTTGTATATAATATCCA TGGTAGGAATTTAAAGTCCAACTGGGAAATATGGTTTAAGAAGTAAACCAATACAGAGTA CCATATAATTGTTGGTATGACAGAATATCTTCCCCCGCCATGAATTAATAATGGCCATTG CTCACTTGTAGAAGAAAGCATTGGTTTTGCTAGTGAAAACGTTAATGTTAGTATTGCGAA AACTATTGCCGAGCGCATGGGGTAATTGGAAACAATAAATGTAAAAATAGTGATGGAAAG ACAAATCATTGTAATTGCAATGCAAATTGAATCATGATTCCATAAAGGTGGCAAAAAGTC ACCATTAGCCCATAAACCCAGAAAAACCTTTGTTGTTAATATTTTGCAAAGTGTTGCGAA ATTAGCTCCAAGAACCATATCAACTCTGGTCTCAGAGGATGTCATGATAATAGAAATAAA TTGAATCAAACAAATAGCAATGAAAACGTATTCGTGAGTGGTGATTTTTTTTGTAGATAA GCGTTTTTGTATAAGTATATTTATCCCTACCATTGGAGCCATGAACACTATAAATGGGCC ACTTAGTCCACATATGATTATCGCTATATAATCGTGTGCTTTTTGATAATTATTTGTAGG CTTTGGAGCTAACATAACAAGAAGTAAATATAGTGATAAATACCAATGATCATTAGTAAC ATTGGCGTGCACTTCTGATACTTCCGGCATTGTTATAATAAACAAAGCAGTAAATATTCT TGGTGTTATGTTTACGTAACTAAATCTTCCAGAGAGTATGAAAGATACAAGCAATGCCCT AACAATAATTGCGGAGATGTTAAAAATTAAAGGGGCATACATTAAATTAAAATTTAATGA TATGGAGGCAATAAGTTTTGATATGGTTTGATAATATCCATTTTGAGGGAATATCATTGA TGTGAATATCCCATTATTGTATGCCATAGCATACCATACATGAGCATCTTCTGCCCAAAA CTGCGGTGCTCTGATTATATCAGGACGGCGCAAATACATCAAAATAACTGCAATGAAAAA TACACCAATTAAGAAAAATAGTTTTTTTACATATGATGTTTTAAGGCTTTTCAT bcftools-1.21/test/csq/EDUMMY0001/EDUMMY0001.fa.fai000066400000000000000000000000221467060157400206710ustar00rootroot00000000000000chr1 1254 6 60 61 bcftools-1.21/test/csq/EDUMMY0001/EDUMMY0001.gff000066400000000000000000000004231467060157400203140ustar00rootroot00000000000000chr1 . gene 1 1254 . + . ID=gene:gtrV;Name=gtrV;locus_tag=locus0000;gene_biotype=protein_coding; chr1 . transcript 1 1254 . + . ID=transcript:gtrV;Parent=gene:gtrV;locus_tag=locus0000;gene_biotype=protein_coding; chr1 . CDS 1 1254 . + . Parent=transcript:gtrV;gene=gene:gtrV bcftools-1.21/test/csq/EDUMMY0001/starts-with-1.txt000066400000000000000000000017501467060157400215230ustar00rootroot000000000000001 T TTAACTACCATTCAACAT frameshift|gtrV|gtrV|protein_coding|+|1LRLFFY*>1LTTIQH*|1T>TTAACTACCATTCAACAT+175T>C+198C>G+202C>G+213G>A+274C>T+313A>C+471G>A+472C>T+544A>T+554A>G+607C>A+643G>T+706C>T+718G>A+872G>A+946T>C+1090C>G+1124G>C+1149C>T+1189T>C+1205C>G 1 T TTAACTACCATTCAACAT frameshift|gtrV|gtrV|protein_coding|+|1LRLFFY*>1LTTIQH*|1T>TTAACTACCATTCAACAT+175T>C+198C>G+202C>G+213G>A+274C>T+313A>C+471G>A+472C>T+544A>T+554A>G+607C>A+643G>T+706C>T+718G>A+872G>A+946T>C+1090C>G+1124G>C+1149C>T+1189T>C+1205C>G 175 T C @1 175 T C @1 198 C G @1 198 C G @1 202 C G @1 202 C G @1 213 G A @1 213 G A @1 274 C T @1 274 C T @1 313 A C @1 313 A C @1 471 G A @1 471 G A @1 472 C T @1 472 C T @1 544 A T @1 544 A T @1 554 A G @1 554 A G @1 607 C A @1 607 C A @1 643 G T @1 643 G T @1 706 C T @1 706 C T @1 718 G A @1 718 G A @1 872 G A @1 872 G A @1 946 T C @1 946 T C @1 1090 C G @1 1090 C G @1 1124 G C @1 1124 G C @1 1149 C T @1 1149 C T @1 1189 T C @1 1189 T C @1 1205 C G @1 1205 C G @1 bcftools-1.21/test/csq/EDUMMY0001/starts-with-1.txt-l000066400000000000000000000035431467060157400217560ustar00rootroot000000000000001 T TTAACTACCATTCAACAT frameshift|gtrV|gtrV|protein_coding|+|1LRLFFY*>1LTTIQH*|1T>TTAACTACCATTCAACAT+175T>C+198C>G+202C>G+213G>A+274C>T+313A>C+471G>A+472C>T+544A>T+554A>G+607C>A+643G>T+706C>T+718G>A+872G>A+946T>C+1090C>G+1124G>C+1149C>T+1189T>C+1205C>G 1 T TTAACTACCATTCAACAT frameshift|gtrV|gtrV|protein_coding|+|1LRLFFY*>1LTTIQH*|1T>TTAACTACCATTCAACAT 175 T C @1 175 T C missense|gtrV|gtrV|protein_coding|+|59Y>59H|175T>C 198 C G @1 198 C G synonymous|gtrV|gtrV|protein_coding|+|66V|198C>G 202 C G @1 202 C G missense|gtrV|gtrV|protein_coding|+|68L>68V|202C>G 213 G A @1 213 G A missense|gtrV|gtrV|protein_coding|+|71M>71I|213G>A 274 C T @1 274 C T missense|gtrV|gtrV|protein_coding|+|92P>92S|274C>T 313 A C @1 313 A C synonymous|gtrV|gtrV|protein_coding|+|105R|313A>C 471 G A @1 471 G A stop_gained|gtrV|gtrV|protein_coding|+|157W>157*|471G>A 472 C T @1 472 C T stop_gained|gtrV|gtrV|protein_coding|+|158Q>158*|472C>T 544 A T @1 544 A T missense|gtrV|gtrV|protein_coding|+|182S>182C|544A>T 554 A G @1 554 A G missense|gtrV|gtrV|protein_coding|+|185N>185S|554A>G 607 C A @1 607 C A missense|gtrV|gtrV|protein_coding|+|203Q>203K|607C>A 643 G T @1 643 G T missense|gtrV|gtrV|protein_coding|+|215D>215Y|643G>T 706 C T @1 706 C T missense|gtrV|gtrV|protein_coding|+|236H>236Y|706C>T 718 G A @1 718 G A missense|gtrV|gtrV|protein_coding|+|240A>240T|718G>A 872 G A @1 872 G A missense|gtrV|gtrV|protein_coding|+|291C>291Y|872G>A 946 T C @1 946 T C missense|gtrV|gtrV|protein_coding|+|316Y>316H|946T>C 1090 C G @1 1090 C G missense|gtrV|gtrV|protein_coding|+|364P>364A|1090C>G 1124 G C @1 1124 G C missense|gtrV|gtrV|protein_coding|+|375S>375T|1124G>C 1149 C T @1 1149 C T synonymous|gtrV|gtrV|protein_coding|+|383C|1149C>T 1189 T C @1 1189 T C missense|gtrV|gtrV|protein_coding|+|397C>397R|1189T>C 1205 C G @1 1205 C G missense|gtrV|gtrV|protein_coding|+|402T>402S|1205C>G bcftools-1.21/test/csq/EDUMMY0001/starts-with-1.vcf000066400000000000000000000020501467060157400214540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=dummy.fa ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 1 . T TTAACTACCATTCAACAT . . EXP=frameshift|gtrV|gtrV|protein_coding|+|1LRLFFY*>1LTTIQH*|1T>TTAACTACCATTCAACAT+175T>C+198C>G+202C>G+213G>A+274C>T+313A>C+471G>A+472C>T+544A>T+554A>G+607C>A+643G>T+706C>T+718G>A+872G>A+946T>C+1090C>G+1124G>C+1149C>T+1189T>C+1205C>G chr1 175 . T C . . EXP=@1 chr1 198 . C G . . EXP=@1 chr1 202 . C G . . EXP=@1 chr1 213 . G A . . EXP=@1 chr1 274 . C T . . EXP=@1 chr1 313 . A C . . EXP=@1 chr1 471 . G A . . EXP=@1 chr1 472 . C T . . EXP=@1 chr1 544 . A T . . EXP=@1 chr1 554 . A G . . EXP=@1 chr1 607 . C A . . EXP=@1 chr1 643 . G T . . EXP=@1 chr1 706 . C T . . EXP=@1 chr1 718 . G A . . EXP=@1 chr1 872 . G A . . EXP=@1 chr1 946 . T C . . EXP=@1 chr1 1090 . C G . . EXP=@1 chr1 1124 . G C . . EXP=@1 chr1 1149 . C T . . EXP=@1 chr1 1189 . T C . . EXP=@1 chr1 1205 . C G . . EXP=@1 bcftools-1.21/test/csq/EDUMMY0002/000077500000000000000000000000001467060157400163315ustar00rootroot00000000000000bcftools-1.21/test/csq/EDUMMY0002/EDUMMY0002.fa000066400000000000000000000030711467060157400201440ustar00rootroot00000000000000>1 ATGAGCTTACGTGAAAAAACCATCAGCGGCGCGAAGTGGTCGGCTATTGCCACGGTGATC ATCATCGGCCTCGGGCTGGTGCAGATGACCGTGCTGGCGCGGATTATCGACAACCACCAG TTCGGCCTGCTGACTGTGTCGCTGGTGATTATCGCGCTGGCAGATACGCTTTCTGACTTC GGTATCGCTAACTCGATTATTCAGCGAAAAGAAATCAGTCACCTTGAACTCACCACGCTG TACTGGCTGAACGTCGGGCTGGGGCTTGTGGTATGTGTGGCGGTGTTTTTGTTGAGTGAT GTCATCGGCGACGTGCTGAATAACCCGGACCTGGCACCGTTGATTAAAACATTGTCGCTG GCGTTTGTGGTGATCCCCCACGGGCAACAGTTCCGCGCGTTGATGCAGAAGGAGCTGGAG TTCAACAAAATCGGCATGATCGAAACCAGCGCGGTGCTGGCGGGCTTCACTTTTACGGTA GTTAGCGCCCATTTCTGGCCGCTGGCGATGACCGCGATCCTCGGTTATCTGGTCAATAGT GCGGTGAGAACACTGCTGTTTGGCTACTTTGGACGCAAAATTTATTGCCCCGGTCTGCAC TTCTCGCTGGCGTCTGTGGCACCGAACTTACGTTTTGGTGCCTGGCTGACGGCGGACAGC ATCATCAACTATCTCAACACCAACCTTTCAACGCTGGTGCTGGCGCGTATTCTTGGCGCG GGCGTGGCAGGGGGATACAACCTGGCGTACAACGTGGCCGTCGTACCGCCGATGAAGCTG AACCCAATCATCACCCGCGTGTTGTTTCCGGCGTTTGCCAAAATTCAGGACGACACCGAA AAGCTGCGTGTTAACTTCTACAAGCTGCTGTCGATAGTGGGGATTATCAACTTTCCGGCG CTGCTGGGGCTGATGGTGGTGTCGAATAACTTCGTACCGCTGGTATTCGGCGAAAAGTGG AACAGCATTATTCCGGTGCTGCAATTGCTGTGTATTGTGGGTCTGCTGCGCTCCGTGGGT AACCCGATTGGTTCGCTGCTGATGGCGAAAGCGCGGGTCGATATCAGCTTTAAATTCAAC GTATTCAAAACATTTCTGTTTATTCCGGCGATTGTTATTGGTGGGCAGATGGCGGGCGCA ATCGGCGTCACGCTCGGTTTCCTGCTGGTGCAGATTATCAACACCATTCTGAGTTACTTC GTGATGATTAAACCGGTTCTTGGTTCCAGTTATCGCCAGTACATCCTGAGTTTGTGGCTG CCGTTTTATCTCTCGTTGCCGACGCTGGTGGTCAGTTATGCGCTGGGCATTGTGCTGAAA GGGCAACTGGCGCTGGGGATGCTGCTGGCGGTGCAAATAGCCGCGGGCGTGCTGGCGTTT GTGGTGATGATTGTGCTGTCACGCCATCCGCTGGTGGTGGAAGTGAAGCGTCAGTTTTGT CGCAGCGAAAAAATGAAAATGCTTTTACGGGCGGGGTGA >2 ATGAGCTTACGTGAAAAAACCATGAGCGGCGCGAAGTGGTCGGCTATTGCCACGGTGATC bcftools-1.21/test/csq/EDUMMY0002/EDUMMY0002.fa.fai000066400000000000000000000000371467060157400207010ustar00rootroot000000000000001 1479 3 60 61 2 60 1510 60 61 bcftools-1.21/test/csq/EDUMMY0002/EDUMMY0002.gff000066400000000000000000000007401467060157400203200ustar00rootroot000000000000001 . gene 1 1479 . + . ID=gene:wzx1_5;Name=wzx1_5;locus_tag=locus0000;gene_biotype=protein_coding; 1 . transcript 1 1479 . + . ID=transcript:wzx1_5;Parent=gene:wzx1_5;locus_tag=locus0000;gene_biotype=protein_coding; 1 . CDS 1 1479 . + . Parent=transcript:wzx1_5;gene=gene:wzx1_5 2 . gene 22 30 . + . ID=gene:g2;Name=dummy2;gene_biotype=protein_coding; 2 . transcript 22 30 . + . ID=transcript:t2;Parent=gene:g2;gene_biotype=protein_coding; 2 . CDS 22 30 . + . Parent=transcript:t2 bcftools-1.21/test/csq/EDUMMY0002/boundaries.txt000066400000000000000000000010001467060157400212140ustar00rootroot000000000000006 C A missense|wzx1_5|wzx1_5|protein_coding|+|2S>2R|6C>A 6 C A missense|wzx1_5|wzx1_5|protein_coding|+|2S>2R|6C>A 1474 G C missense|wzx1_5|wzx1_5|protein_coding|+|492G>492R|1474G>C 1474 G C missense|wzx1_5|wzx1_5|protein_coding|+|492G>492R|1474G>C 1479 A C stop_lost|wzx1_5|wzx1_5|protein_coding|+|493*>493C|1479A>C 1479 A C stop_lost|wzx1_5|wzx1_5|protein_coding|+|493*>493C|1479A>C 11 GTGAAAAAACCATGA G coding_sequence|dummy2|t2|protein_coding 11 GTGAAAAAACCATGA G coding_sequence|dummy2|t2|protein_coding bcftools-1.21/test/csq/EDUMMY0002/boundaries.vcf000066400000000000000000000010041467060157400211570ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=EDUMMY0002.fa ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 6 . C A . . EXP=missense|wzx1_5|wzx1_5|protein_coding|+|2S>2R|6C>A 1 1474 . G C . . EXP=missense|wzx1_5|wzx1_5|protein_coding|+|492G>492R|1474G>C 1 1479 . A C . . EXP=stop_lost|wzx1_5|wzx1_5|protein_coding|+|493*>493C|1479A>C 2 11 . GTGAAAAAACCATGA G . . EXP=coding_sequence|dummy2|t2|protein_coding bcftools-1.21/test/csq/EDUMMY0003/000077500000000000000000000000001467060157400163325ustar00rootroot00000000000000bcftools-1.21/test/csq/EDUMMY0003/EDUMMY0003.fa000066400000000000000000002272611467060157400201570ustar00rootroot00000000000000>4 4:699438-775637 CTCCCTCCGCCGAGTCCAGGCCCGACGCGCCTGCGCCCTCTGAACACGCCCCTCCCCGCC CCTATCCCCACCCCTTACCGCCTGGCCCCGCCCACGCCCCTTGCCGCGGGGTGGGAGCCC AGACGCACACCGCGCATGCTCCGAGCGCGGCGCCCCCGACGCGGCGCTCGGCTCGGCTCG GGCATTTCCGCCTCTTTGTTTTAAACTCCGGACGGGCTTTTTTCTCCTCCTCTTGGGGGG GACCCAGAGGGAGCGGCGCCCCCTCCCCCCTCCGGCGCGGACCCCGCGTGCGCCTTGCTC GCCCGCAGCCCCGAGACCGCAGGTCAGTGAGTCCGCCCCGCCTGGCCTGGGCCCTCGGCG CCCGCTCCTCAGGCTGCGGCCTCGGCCCGTGTCCGGCCCGGAAGGCTCCGAACCCCGGGC CCGCGCTCCGTCGTCCCCGTCGGCCTGGCCCGGGAAGCCCTTGGCAGGCCCGGGAGGGCC GGCACCCCAGCCCAGTCAGGACTCCGGGAGGTCGAAGACCCCAGCCCAGGCAGGACTCCG GGAGGGCCAAGAGCCCAGCCCAGGCAGGACCCCGGGAGGGCTGGGACTCCAGCCTAGGCA GGACGCAGGGAGGGCAAGACCCCAGCCCAGGCAGGACTCCGGGAGGTCGAAGACCCCAGC CCAGGCAGGACCCAGGGAGGGCTGGGACAGCAGCCCAGGCAGGACGCAGGGAGGGCAAGA CCCCAGTCCAGGCAGGACGCAGGGAGGGCAAGACCCCAGCCCAGGCAGGACTCCGGGAGG TCGAAGACCCCAGCCCAGGCAGGACCCAGGGAGGGCAAAGACCCCAGAACAGGGAGGGCC AAGACCCCAGACCAGGCAGGACCCCGGGAGGGCCAAGACCCCAGACCAGGCAGGACCCAG GGAGGGCGAAGACCCCAGCCCAGGCAGGACCGCGGGAGGGCAGGGACCCCAGACCAGGCA GGACCCCGGGAGGGCCAAGACCCCAGACCAGGCAGGACCCAGGGAGGGCGAAGACCCCAG CCCAGGCAGGACCGCGGGAGGGCAGGGACCCCAGACCAGGCAGGACCCTGGGAAGGTCGC GACCCCAGCCCAGGCAGGACCCAGGGAGGGCGAAGACCCCAGACCAGGCAGGACCCAGGT GAGGGCGAAGACCCCAGCCCAGGCAGGACCGCGGGAGGGCAGGGACCCCAGACCAGGCAG GACCCTGGGAAGGTCGCGACCCCAGCCCAGGCAGGACCCAGGGAGGGCGAAGACCCCAGA CCAGGCAGGACCCAGGTGAGGGCAAAGACCCCAGCCCAGGCAGGACCGCGGGAGGGTAGG GACCCCAGCCCAGGCAGGACCCTGGGAAGGTCGCGACCCCAGCCCAGGCAGGACCCCGGG AGGGCTGGGTCTTCAGACCAGGCAGGACCTGAAGAGAGTTGGGCTCTGGGATTGCACAGG ACCCCCAGAGTGCTAGGACACAATGACACATCATCCAGGAGGGTCTGACCCTGGGACAGG TCACCGAGAAGGGCTGGGACCCCAAGATGGGTCACCAAGGAGGGTCGGACCTGGCCACCT GGCAGGGCCCGGGGGGGCTAGGACCCTGGGAAGAATCACGGAGGAGGGCCAGACGTAGGG ACCAGGCAGAATCCAAAGAATGCCAGGACCCCAGAATAGATCCCCCAGGAAGGTCCTGCC TTAAAGTGGGTCACAGACGAGGGCCAGGACCCCATGACCATAATTCAGGAGGACCTGACC CTGGAGCAGTCTTGTGAGTCCTGTGAGCACTGCTGGGACCCTGAGACTGCCCCGTCTCCC CCGGGACCCTGAGACAGCCCTGTTTTCCCCTGGGGGCCGGGACCCTGGGACAGCCTGTTT TCACCCGGGGGCCGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGTCGGGACCCTGGG ACAGCTCTGTTTTCCCCTGGGGGTCGGGACTCTGGGACAGCTCTGTTTTCCCCTGGGGGT CGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGTCGGGACCCTGGGACAGCTCTGTTT TCCCCTGGGGGCCGGGACCCTGAGACAGCTCTGTTTTCACCTGGGGGCCGGGACCCTGAG ACAGCTCTGTTTTCACCTGGGGGCCGGGACCCTGGGACAGCTCTGTTTTCCCCTGGGGGC CGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGTCGGGACCCTGGGACAGCCCTGTTT TCACCTGGGGGTCGGGACCCTGAGACAGCCCTGTTTTCCCCTGGGGGTCGGGACCCTGGG ACAGCCCTGTTTTCCCCTGGGGGCCGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGT CGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGCCGGGACCCTGGGACAGCCCTGTTT TCACCTGGGGGCCGGGACCCTGGGACAGCCCTGTTTTCACCTGGGGGCCGGGACCCTGAG ACAGCCCTGTTTTCTCCCAGGGCCCGGCACCCTGAGACTGGACAGTGAGAAGGGCTCATG ACATGGACAGGCTTCTAGATGACCAGGACCTCAAACGGGGTCACTTAGGGTCGGGACACT GGTGTGGACTGGGAAGAAGGCTAGGCTCTCAAAGAGGACCTGATGAGAGCTGGAACTTCC AGACAGGTCCTCAGAGGGCTGGGACTCCTGAACAAGTCACTGAGGAGCATGTAGGCCCCA AGACTGGACTGTAAGGAGTACTGGGACCCTCGGGGGGGAATCCAGCAGTGTCCTGAATCT GCCCAGTCCACTCAGCTGGATGCACCTGCTGTGAAGGCCAGGCATCTGGCATCCTGGTAC CCGAGGCCCTTTCCATGAGACCCTGGGCCAGCCCCACAGCCCCTGCACATGAACCGCCTA GGTGATACCTGGGGTAGGTATGAGGCAGGGGCCTCAGGGTTCCAGGAGCTCCCAGCCCAC AGGCTCCACACCTCAGGCTGGCACTGCACCCTCCCACTCAGCCCCTCGTCCGGGGCTGCT GTCCTGTCCTTGCCTTGGCTGTGGTCCGTGTCCAGCACCTTCAACCCCTCCTGCCCCTCT CCCCATCTTCAAGGTCATGTGAGTGCCCCACTTCCTCAGTGTAGAGGCGTTTCCAGTGTC CGGGAGACTTGGAGGAGGGGTGGGGTCTGAGCTGGGATGTGGACTCCTGGGCATATTTTG GGGACAGTTGGTCCAAGTCAGGAAAGTTGGAGCAGGCAAGGCTATTTCCCACTCCCTCTC TAGTAAGGGAAGGAATTAAAGGATCCTGGTGGTGATCGGGCTGGGGACGGGGGTTGGTTT ATTTCTCTGAAACCTTTGAATCAGCCTTTTATCAAAAACTTGTGGGTGTTTTCCTTTAAT TTGGAAGTGGTAATGAAAAAGTGGGGTGCATGAGGTATTCAGAAGCGAGCGGTCTATGCT GTCCTTTGACTAGGGAAGGGTTGTCTAGTGACATCTTGTCAGGGGTGTTTCCAGAGGGTG GTCATCCCAGGAACCCTGCTCCCAGAGGGTGCCGTGTGGCTGCTTGGTGTGCCGTACATT CCCCAAAAGAGTGAATGATGCATGAACGAATGAAAGGCAAGAGTGAATGATGCATGAACA AATGAATGAAAGGCAAGAGTGAATGATGCATGAACAAATGAATGAAAGGCAAGAGTGAAT GATGCATGAACAAATGAATGAAAGGCAAGAGTGAATGATGCATGAACAAATGAATGAAAG GCAAGAGTGAATGATGCATGAACACATGAATGAAAGGCAAGAGTGAATGATGCATGAACA AATGAATGAAAGGCAAGAGTGAATGATCCATGAGCAAATGAATGAAAGGCAAGCGTGAAT GATCCATGAACAAATGAATGAAAGGCAAGAGTGAATGATGTATGAACAAATGAATGAAAG GCAAGAGTGAGTGATGCATGAACAAATGAATGAAAGGCAGGGCCGCTCTTCAGAGACATC CCCTCGGATTAGGCGTGCGGGCTTGCCTGGAAGTTGGGCAGTACAATGAGGTGTAACCCT AAAACTCTGAGCTATCTAGACTCCCAAGAGAGACACTGAATTGGATGGTTCGGGATTTCA TCTTTGCCACAGCTTCACTTCTTGGTTACTTAGGAGAAAACCGTGTTAGGTTTTCAGCTT AACATTTCAGGGTACTCAGTGTCAGCCACGTCGTGTCCCTGCGTGGTCAGCCTGGACCTA GAAGCTCTTACTCGCCCAGTGTAACCGCCAGGGACCTTTTTACTCAACACTTCCTTCTGA TTTGCTCTTTTGACATATCCTTTACTGTTTTTTAAACTTCATTTGCTTTGTGAAATTGTG GAAGAGGCTTGTGAAGCTGAGTGTTCAGGTTTGTTTGGCTCTGTACTGTCTGGTTCCCAG GCTTTTAGAGGTGTGTTTTAGAGGTGTTTTTAGGCCGTGCTGAGTGGTTGTATTATTTAT ATATTGCTGTGTGGCAGATTACCCCAGAACCCCTGCCTTAAACCAACAGTCCGATGATAA CTTACTGTTTCTGTGGGTTGGGAGACCAGGTGGGCTCTGGCTCAGGGACCTCCCATCTGG GGTTGTGTCTCCTCTGAAGGCTGGACTGGGGAGGGTCCGCAGCCAGGCTGTGTCACGTGA CTGTGGGCTGGAGACCTCAGTTCCTTTCTCTATAGGGCAGCTCCGAGGGAGCCCATGCCT AGCCAGAGAGGGACAGGAAGGACGTCCCAGTGTTTGTGGAGTGACATTCTACCACTTTTG CCAAGAGTCATTCGGCCCCTACACACTTGAGGGGAGGGGACTCCAAAACGGTGAGCATAC GATGGGCAGGTGGGGTCACTGGAACACTTAAAGCCTGCCCAGCACAGCGGTGCTGTGAGC CTGGCACCTCTCAGGGCACTGGAGAGACATCCCGTAAGTAAATCAGCGATTGCGTGTGGA GTGACGTGTTAAGATGAGGATGTGACTGTTCAGCTGTCTCTTTAATTGGTGTGGGTTTCT CCGATGTCACCGTCATGATTGAGATATTTGTGATACGTAAAAGAAGATAAATTACAGATA GAAAAGATTCTTAGGAATTAACTTGCAATTTGGCATACCAGTAGCAAGCCAAAAGACCCC CCCACAAATTAAATTACAAGGTGTGTGTCACTGATGTCAAATCCTTCCCAACAGCTTCAA GTGCAAGGATTTTTGCTGTTCCCAGAGTCCCCTCATTTTCTTCCTGCCAGTGATTTTGCT CCAGAAATTATCAACCGACTTCTGTTAAGTTTTCCTAAACCATTTTAAATATATGGGGGA AATGTTTTTACCAGTTACAGTAGACCTTGCGCTTGCAGTTATTTGTGACTTCATAAAAAT GCCGTAGGAGACGTGAGACCTTGACCACACTGGACATTTGACCGGTGTGAGGACTTAGCT CCAGGGTCCAGGCACTACTGTGAGCCAGAGCCTCTGCTCCTAGCCCACACCCTCCACTGC ACAGGGAGCCGGACCCCATGCCTCCTTCCGGTTCTGGGCTGGAGCTAGGGCCGGGAAGGG GGCCTGTTCTGGACTCTGGAGACCTCAGCCGCCCCTCCCACCATGCCGCACTCTCTAGAC TACAGCGGCTCTGTGGCAAAATCGAGGAGCTGCAGGGTGCGGCAGGGGCCCTTTGCCGTG GGCTAGAATTCTTTACTTGGGTTTTTTTATTTGGATTATAAAGTGAGTCTTGTTTTGGTG TATGCTGTTACTCTTTATTAAATGGCAGGATTTATTTTGTTTGCAGCCTTATTTTTGGTT AATGGTTAGAATTGAAGTTGAAAATGTAATTTTTCTTTTTTTTTTCTTTTTTTTTTTTTT GAGACGGAGTCTCGCTCTGTCGCCCAGGCCGGACTGCGGACTGCAGTGGCGCAATCTCGG CTCACTGCAAGCTCCGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAG CTGGGACTACAGGCGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACG GGGTTTCACCTTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCTC GGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCGAAAATGTAATT TTTCTACAGAATTAGGCAGGCGTGTGTAATTTTTCAACAAAAATTAGCCAGGCATGGTGG TGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGG AAGCGGAGTTTGCAGTGATCTGAGATTGCACTCCAGACTGGGCGAAGAGTGAGACTCTGT CTGAAAAAAAAATAAAAAGTAAAAAAAAAAAGAAAAGAAAATGTAATTTTTCTTTTACCA TTGAAATATAGTGAGGTTTAGGGACAGTTTCCTATTGTTTATCTATTTTTTATTATGATA CTTGCTGTTAATATAGCAAAAATATGGTACAATTCATTGTGCTTCAAAAATTGAAATTAT TTTTAATTTCATACATTGATAGTTTATCACTGAATTTTAAAAATGTGAGGCCTTAAGAAA AACAAAACAAAACTATCTTTCCAGATCTGCCACGTTTCTCCCGACAGAACTGAATTATGC AAATGCCAAAATGACAAAGAACAATAGTGAATGTTGCCTAGGTGCATTTTTGTAGAATTA TCCACTGAGTTAAGCAAAACTCCCATTGACAGGAACTCACACTCTAGAAAATATAGTCCT TCAACCTATTGTTATATTGACTTGCTTTTTTTTAAGATAAACTCTAATATTCGTGTTTGT TTGTTTGTTTTTGTTTTTTGTTTGTTTGTTTGTTTTGAGATGGAGTTTTGCTCTTGTAGC CCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCTGGTTCAAG TGATTCTCCTGCCTCAGCTCCCTAAGTAGCTGGGATTACAGGCGCCTGCCACCATGCCCG GCTAAGTTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCA AACTCCTGACCTCATGACCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTG AGCCACCGCGCCCGGCCAATAAACTCTAATATTTAGGTGCATTTAGAGAGTGGATTTGTT GGCTTGGTTTCTTTTTTCTTTTTTTCAAATTCATTGATATTTGCTGGGCTTTGCTACATT AACAGCAAATTCCAGATGTTTAATGAGAAATAGATGCAAAGAGGGGAAATCTGTCTGCAG ACTTCCTTGAAACTCCCTCTAATCAGTGGGTCCCGTTGGCCTTGTGGGTCTTATGGGGGC TGTGAGCCTCGTGGGAGCTGTGGGCCTCATGGGGGCTGTATGGCCTTGTTGGGGGCCTGT GGGGCCTGTGGGCCCTGTGGGGGGCTGTGTACCTCCTGGGGGCTGTGGCCAAGTGGGTCC TATGTTCTTCGTGGGTCCTGTGTGGTCTGGTGGGGGCTGTGGCCTCGTGGGAGCTGTGGC TTTGTGAGTCCTGTGTGGCGTCATGGGGGCTGTGGCCTTGTGGGTCCTGTGTGGCCTGGT GGGGGCTGTGGCCTTGTGGGTCCTGTGTGGCCTGGTGGGGGCTGTGGCTTCATGGGTCCT GTGTGGTCTGGTGGGGGCTGTGGCCTCATGGGGGCTGTAGCCTTGTGGGTCCTGTGTGGC CTGGTGGGGGCTGTGGCTTTGTGGGTCCTGTGTGTCTCATGGGAGCCGTGGCCTTGTGGG TCCTGTGTGGCCTTGTGGGGGCTGTGGCCTCGTGGGGGCTGTGGCCTCATGGGTCTTGTG TGCCTTGTGGGGGCTATGGCCTCATGGGTCCTGTGTGGCCTGGTGGGGGCTGTGGCCTTG TGGGTCCTGTGTGGCCTCATGGGTCCTGTGTGGCCTCGTCAGGGCTGTGGCCTCATGGAT CCTGTGTGGCCTCGTGGGGGGCTATGACTTTGTGCCTGTGTCTCCTGTCTGGGTCTTGTG AGCTGTCACATTTCCAGGTTCTTGATCAGGGCGTGGCCCGTATTAGATGCTCAATAAACA GTAACCGGAAGCTGATCCTCATGGATGCTGTGTGGAGCTGTTCTGAGGCGGCATGAGTAT GAACTTGTTGGATTCCTGATGCCGCCCAGGAATCAGACCGTAAAAGCTGTGCTTATTTCG CAGTGTGAGCCTGGCACAGCAGAGGGCGCACAGGGCAGGCATCATTGGAATGTGGGGGCC ACGAGGGCTCACCTTAAAATTTTTTAAATGTTAAGTGATTTTAATTTACTTTTTTACCCA AGTTTTTGTTAAGAAAAAAAATCGCAATACAGAAAAATGGAGAAAATTATACAGTGAGCA CTTGCTGTGGTCCGAACGTCTGTGTCCCCCAGAATCCATGGGGGACCCTAACCCCCAAGG TGTCAGTGTCAGGCGTGGGGCCCTCGGAAGGCTCTGCCCTGATGACAGGACCAGCGCCCT TTCTGTCATTTGAGGACACGAGAGAAGGCACTGCCTGTGAGGACTCTGACCCCACCAGCC CCCAAATCTGCGAGCGCCTTGATTCTGGACTCCCAGCCTGCAGAACTGAGAGGTGCGTTC TGTGGTTTGTCAGCTGCTCGGCCTAAGGTGCTTCGGTCGCAGCCGCCTGAACAGACCAGG ACGGCACCCTCTACTGCCCAGACCCACTCGTGGCCGTTCGGCCGCATTTGCTTCCTCTCC TTCTCTCAGTACATCCTGGACTCACCTGTGAGCGGCTCCGGACAGGAGCCTTGCTGGGAA GGTGAGTCCCACCTGAGAGCAAGAACTAGGGGAGGCCCCCACACCGCTACAACCCCACTG TGACCCTAGGACGGTGGCACCTACTTCACGGCGTTACCTGATTTTCAGGCCGCCTTACCT CTTCCCAGCTGTCTTGAGAATGTCTCCATGTTTTCCTGAACCAGAGTCAGCCAGGGCCTG TCCTTGCCCTGGAGGTCCTGGCCCTTCTGACCATGCCAGGTGAGACCCCCTGGCGTTGGA GGTCTTGTCTCCCTGTCCGTGGACCGGGCTCGCATCCTTCCCACCCCACTGCCTTCTGCC AGGCCAGCGGAGACATAGGCCCTGACGTCCTCTTCAGTCTCAGCTGGAGAAAGCTGCCCT GGAGGGACTCTTCTCACTAGGTCACGCAAACCTGGGCACTCCCGATTTTGAGGTAGCTTA TTTGGGACCTTAATTACAGCTTCAAAAGTCCCTTTACAGCAGTCCATGGGTCAGTATGTC AGTAACAGAACTGGGCGTCGGTTCTGGGACCCTGTAGACACTGAGGGTGAGAACTGGGTG TCGGTGCTGGGACGCTGTAGACGCTGTGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCC TGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTG AGAACTGGGCGTCGGTGCTGGGACCCTGTAGACTCTGTGAGTGTGAGAACTGGGTGTCGG TGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGA CACTGCGAGTGTGAGAACTGGGTGTTGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAA CTGGGTGTCGGTGCTGGGACCCTGTAGACACTCAATGTGAGAACTGGGAGTCGGTGCTGG GACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCTTGTAGACACTGT GAGTGTGAGAACCGGGCATCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGCACTGGGC GTCGGTGCTGGGACCCTGTAGACACTGTGAGTGTGAGAACTGGGCGTCTGTGCTGGGACC CTATAGACACTGAGTGGGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGT GAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGTGAGTGTGAGAACTGGGTGTCG GTGCTGGGACCCTGTAGACACTTAGTGTGAGAACTGGGCGTGGGTGCTGGGACCCTCTAG ACACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGA ACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGTGAGTGTGAGAACTGGGTGTCGGTGC TGGGACCCTGTAGACACTTAGTGTGAGAACTGGGCGTGGGTGCTGGGACCCTCTAGACAC TGTGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGAGGGTGAGAACTG GGCGTCGGTGCTGGGACCCTGTAGACACTGAGGGTGAGAACTGGGCGTCGGTGCTGGGAC CCTGAAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTG TGAGAACTGGGCGTCGGTGCTGGAACCCTGTAGACACTGTGAGTGTGAGAACCGGGCATC GGTGCTGGGACCCTGTAGACACTGAGGGTGAGAACTGGGTGTCAGTGCTGGGACCCTGTA GACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGAACCCTGTAGACACTTAGTGTGAGAA CTGGGCGTGGGTGCTGGGACCCTCTAGACACTGTGAGTGTGAGAACTGGGCGTCGGTGCT GGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTGGACACT GCGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTGGACACTGTGAGTGTGAGAACT GGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGA CCCTGTGGACACTGCGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGC GAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGCGAGTGTGAGAACTGG GCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGTGTCGGTGCTGGGACC CTGTAGACACTGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTAGACACTGTGTGA GAACTGGGCGTCGGTGCTGGGACCCTGAAGACACTGAGTGTGAGAACTGGGCGTCGGTGC TGGGACCCTGTAGATACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGAT ACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTCTAGACACTGTGAGTGTGAGA ACTGGGCGTCGGTGCTGGGCCCCTGTGGACACTGCGAGTGTGAGAACTGGGCGTGGGTGC TGGGACCCTGTAGACACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGAC ACTGAGGGTGAGAACTGGGCGTCTGTGCTGGGACCCTGTAGACACTGAGGGTGAGAACTG GGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGAGCGTCGGTGCTGGGAC CCTGTAGACACTGAATGTGAGAACTGAGCGTCGGTGCTGGGACCCTGTAGACACTGAATG TGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGAGCGTCGG TGCTGGGACCCTGTAGACACTGAATGTGAGAACTGAGCGTCGGTGCTGGGACCCTGTAGA CACTGAATGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACT GGGTGTCAGTGCTGGGACCCTGTGGACACTGTGAGTGTGTGCTTACTTTTTTTTTCAGTC TTGCTTTGTCACTCAGACTGGAGTGCAGTGGCAGGGTCTCGGCTCACTGTAACCTCCACT TCCTGAGTTCAAGGGATTCTCCCGTCTCAGCCTCCTGAGTAGCTGGGACTGCAGGTGCTT CCCACCACACCCAGCTAATTTTTGTATTTATATTAGCGACGGGGTTTCACTGTATTGGCC AAGCTGCTCTCAAGCCCCTGACCTCGTGATCTGCCCACCTTGGCCTTGCAAAGTGCTGGG ATTACAAGTGTGAGCCACCGCGCCCGGCTGTGTGTGCTTACTTTCAAACAAGGTAGTCTC TGCAGCATACTGAGATGACATTGAGAAGAGGCTTGATAAGGTGCAGGAGGGCGTGTTCTG GGCACAGGGCGCCCTGAGCGAGAGGGCCGAGAATGTCCTGCGGTGATTGAGGAGTCCACG CGGCAGGGGCAGAGGGAGAGGCAAAGGCAGAGGGAGGTGTGGGCTGTTGGCAGGGCCAGG GCCTGACCTCGATGGCCCTGAGGAGCCTCTGCGTCCACTCAGGCTTGTGTGTTCGGGAAT CCCGTGGGTGCTGCGTTGAGGTCAGTGGGGCCTGGTGTGGCAGAGGCGAGGGTGCTGTGT GGGTGCCGCGTGTCCTTCAAGGCACAGCAGATTGGTTTCTAGGGGGGCCCAGTGTGAGGG AGGCGCAGGTGGCTCAGAGGTGTCTGGGGCTCCCTGGGGTGCAAGGCTGTCAGAGGAGGT CAGGGCAGGGAAGTCCTGATGGACGTGCCGGCCGCCCACTGACGTGCAGCCGTCAGACGT CTGGATGGGAGTTCAAAGCAGGGTTGGGCCAGAGGTGCCTGGAGAGGAAACGTGGAGTCG GGGGGTCTGTGGGGTAGCCCCGGGGGCGGCGCTGGGGGCCGGACTGCTGAAGCGCCCCCG AGCTCCCTGGGTATAACCTGCCTGGGCCTCCTGGACAGCTGCAGGCCTGCGGGGCCTGGG TTGAGGGGGATGTCACTGAGCTACACTCTGAGGCTGGTAGTGACTCTCATCTGGGGTCCC ACCTTAGTGAATGTACCTTAGGTCTTTGTATGAACGCAAATATTTGTATAAACACTTAAT TTAAAAAATGAGAGCTGATGTGCGCCTGTAATCCCAGCTACTGAGAAATGTCAGCCCAGC AGTGAGGCCTGTCCAGTCTCAGCCCTGTCCGTGTGAGTGCTGTGCTCTGTGTGTGGCCCC CACAGTGCCACGGTCCACGGAGGTGGGGTCGGCTGGCTCTGGCTGGGAGTTGGGGGCCCA GTTGCTCTAATGCAGGCAACACCCTGAGTGGGGCTGGGAGTCAAGGACCAGGCTGGGGGC TCGATGTCACAGGTGTGGGCAGGAGCCCATGGCCCTCTGAGAGCTTTGTGGCCACGGTAG GGGCTGGGCCATGGGGGAGGCAACTTTACTGCCTGGGGTCAGTTCCTGCCTGGCCAGAGA TGGAGCAGGGATGCTTACTGTCTTTCGAGTCATGGACCCTTTTGAGAATTAAATTCAAAG CGCTGTCATGTTGTAGCATTGTTTTTCATTTTCTTTTTTTTCTTTTTTCTTTTTTTAATT TTTTGAGTTAGAGTCTTGTGCTGTCACCCAGACTGGAGTGTAATGGCACTATCTTGGCTC ATTGCAACCTCTGCTATACAGGTTCAAGCATTTCTCCTGCCTCAGGCTCCTGAGTAGCTG GGACTACAGGCACGTGCCACCATGCCCGGCTATTTTTTGTATTTTTAGTAGAGACGGTGT TTCACCATGTTGGTCAGGCTGGTGTCGAACTCCTGACCTTGTGATCTGCCTGCCTGGGCC TCCCAGAGTGCTGGGATTACAGGTGTGAGCCACCTCACCCGGCTGTTTTTCATTTTCTTA AAAAAACTTTTAGGGTGACATAGCTGTGCAGAGAACCATGTAAAGTTCCGTTTTCCTCCT AACCTGGTCGTCTCCAGCGGGAAGGAACAGAGAGTGCTTGGTGTGGTTCTGTGTGTCCGC ACGAGGTTGATGAGAACCCTCGGTGCCTGGACTGTCTTCTCACCAGGCGCAGCTCAGGAA CATGGTGGTGCCGGAGAGTGGTTTGTGTCTGTTCCTCCCTGGCTGCTGTGAGCCGCCCCC CCAGGTCCTGTGTCCTCCGCGCGGGTTGGCGAGGGAGCTGTGTGTGTCTGTGGTGCAGCT GCAATGCGGGGTCCCGTCAGGGAACAGGAGCGAGGCGTTTACGCCATAAGGAGGTGGAGA AGGGATGGTGTGTGAGTTTGGCAGGTGCTGAGGGCTACAGTGGAGCTGGAGGGGCAGGAC GGTGCAGGGCGGTGCAGGCAGGGTGTTTGGGGTCAGGCCAGCTGTGGAAAGGCCACAGGT GAACCAGGTGCGGAGACAAAGAGCTGGAGGCATCCGGTGGTCTGGCTGGGCCTCATCCGT GTCCTGCCGCTGCTGCAGTGATGCCAGGGGCATGGAAGGGACCCTAGCCCAGCTCCTCCC TTGGCAGTCGGAGCGTCGGGGCCGCATTATAGAGGGAGGGACTCTCCGGACGATGGGAAC GAGAGTCCATTGGGATCGTAGCTGTGGTGCGGTTCACAGCGTTGTGAACAGCTAATGTTG GGCTGGGGGCATCTGTGGGGCCAGTTGCAGCAGTTTGGTCATTTTTGTGTGAAAATAAAT GAAAACAGGTTTTGCAGAGCCCGTTGGTGAAGGCAGGGGTGCCTCTGGCATCGACTGGAT GGCCTTTCCCTCCTGAGTGACAGCCCTGGACGTGCTGTCGCCTCATGAGGACGCCGATGT GGCCCTGCTGCCGGAGTATGCCAAGCACGAGGGGCCAGGTGGCACACAGCACCTGTGTGC CGCTGGGGAGGGTGACCGCGGGAGGAGCGCCCGTGCATCGCTGCAGAGGGTGACTGCGGG AGGAGTGCCCGCCCATGCATCGCTGGGGAGGGTGACTGCGGGAGGAGCGCCTGTGCATCG CTGTGGAGGGTGACTGTGCAGGAGGACAGAGTGCCACAAGGGAGAGCAGCAGAGTGGTTT CAGCTCCGGGAGGTGGGGCTGCCCGTCCAGAGAGGTGCAGGGTCTCTTGTCAGGTGGACA GGGGCTGGCCCACCCGTGAGTGGGTAGGGCCTCCTGCCAGGGAGCCTTGTGCATGGCTGG GAGGACGGCAAGGCTGATGTGGACGCAGCCCCGACGTGAACAGGACCCCACGTGGACGGG CAGTGACGTGCGTGTGGACCCGGGGTGGACGGGCGGTGACGTGCGTGTGGACCCGGGGTG GACGGGCGGTGACGTGCGTGTGGACCCGGGGTGGACGGGCGGTGACGTGCGTGTGGACCC GGCGTGGACGGGCGGTGACGTGCGTGTGGACCCGGCGTGGACGCAGCCCCGACGTGAATG GATGTGGTTCCGACGTGACTGCGCTGGCATGGGAAGCAGAGGGTGAGGCTCGGCTCTGCT GTCAGGAGGACATGTCAGACTTCTGTCTCTAAGATACTGCTCAGACTTGTGTGGAGGGTG AATTAGTGCGAGGGCGGCTTGGAGAAGCCTGTCCTGGGCGGGTTTCACCACTTGGACGGG AGCTCTGGCATGGTCCAGGGAGTGGCCGAGGACAGCAAGGAGGAGATGACCCCATGGGCA AGCAGGAGCTCAGATGGGAGGCATGGAGCAGACGGGACTCCACGTGGCACCACCCCTCCC ACCTGGGCTGGGCACCCATGAGGCTGAGGACCCTGGGGAGGGAACGCTGCTTGTCGGGCG GTGGTGACGATTTCATGGATGTTTGTGAAACCAACCTCACTGCCCCATTACAACAGTGCG GGCCCTGATTCTCATGGTTCCCCAGTGAGGCTGTTCCACGGTGGCACAGGACACGCCTGC AGCTTTGTGCCTGTGAATCTCAGGAGCTGTTTTCTGGAAAGTTCCATAACTCAGCAAAAC TGACTCACAAACAACAGAAACTTCAAGGCTGTCCTAAGATATGGGTGGCAGAAGAAAATG TGCCCCAGGCATGGGCTTGTGATGCCGGCTCTTCCTCCTGGCAGAGCTCCCCAGAGGAAG GCTGGGCTGGGCAGTCAGCCAGACGGGAAAGGGGGCTGAGGCGTCCAGGCTGCAGAGGGT GCCGGGGTGGAGAGCGGAAGAGAGAGGGAGTCGGTGCCTTAGGAGGCTGCGGGCGAGGCG AGGGCAGAGTGCACTCGCTGGGGGTCACCCTGCCCCCCAGGACTCCTTTCACAGGACAGA GAAGCTCCTGGTGAGCGGGGCTGCTGAACGCAGGCCCCAGGGCCTGTAGGACCCTTAGGG AGACGGGTGGCTCTGCGTGTGGGTGTGGAGAGAGGCCTGTGGGAGACGGATGGATGGGTG TCTCTGTGTATGGGCATGGGGAGGGGCCTGTGGGAGGTGGATGGGTTGGGTGGCTCTGTG TATGGGCATGGGGAGGGGCCTGTGGGAGGTGGGTGGATGGGTGTCTCTGCATGTGGGTGT GGAAAGAGGCCTGTGGGAGACTGGTGGATGGGTGGCTCTGCGTGTGGGCGTGGAGAGAGG CCTGTGGGAGGTGGGTGGACATGTGTCGCTGCATGTGGGTGTGGGGAGAGGCCTGTGGGA GGTGGATGGGTTGGGTGGCTCTGTGTGTGGGCGTGGAGAGGCCCGTGGCAGCTCCTTCGT TGCAGAAACCGCATCGGAGCACATCGCGTAGTGCAGGACACACGGGGCGTGGGACGGTGT CTGTGTGAGAGCAGCATCTGTGTGTATGCAGTGTTATCTAAGGACACACCCACAGACACG GACACGTCCTTACGCAGAGAACAGCCGCTGCCTCTTAGTGTTCAGGATGATACGTTTTTC CTTAATATCATCCTTCGCTTTGCACATCATACTGAATACGTGTGTATGTGACTTTTACTG CAAAACAAAACAAAAAGCAGAAGCTACTGTGTTATCCAGACGGCTGTGTGCTGCAGGCGC GACTCAGAACAGCAGCTCCTCCCAGCATCCCGCAGCTAAATGACAGGAGCTGGAGGCTGC CCCAGGCAGCGGCGTGGCTGGCGTGCGGAGTGTTTTGGGGGTGTCTGAGCTGGGTGGAGA GGAAGGCATATGTCACACTGAGGCATCAGAGACACATCCATTCACGTCGGGGCTGTGTCC GCGCCGGGTCCACACTCAGTCATCGCCCGTCCGCGCCGGGTCCACACTCAGTCATCGCCC GTCCGCGCCGGGTCCACACTCGCGTCATCGCCCGTCCGCGCCGGGTCCACACTCAGTCAT CGCCGTCCGCGCCGGGTCCACACTCGCGTCATCACCTGTCTGCGCTGGGTCCACACTCGC GTCATCACCTGTCTGCGCTGGGTCCACACTCGCGTCATCGCCCACCCACGCCGGGTCCAC ACTCGCGACATCGCCATCCACGCCGGGTCCACACTCGCGTCATCGCCATCCACGCCGGGT CCACACTCGCGACATCGCCATCCACGCCGGGTCCACACTCGCGACATCGCCATCCACGCC GGGTCCACACTCGCGTCATCGCCATCCACGCCGGGTCCACACTCGCGTCATCGCCATCCA CGCCGGGTCCACACTCGCGACATCGCCCGCCCGCGCCGGGTCCACACTCAGTCATCGCCC GTCCGTGCCGGGTCCACATTCGCGTCATCGCCATCCACGCCGGGTCCACACTCACGTCAT CGCCATCCACGCCGGGTCCACACTCGCGTCATCGCCCACCCGCGCCGGGTCCACACTCGC GTCATCGCCGTCCGTGCCGGGTCCACACTCAGTCATCGCCGTCCGCGCCGGGTCCACACT CGGTCATCGCCATCCGCGCGGGGATGTGTCTGAAAAGTGTGGTGAGAGCTGTGTTCCCTG CGCATTTCTGAAGGCTCCTAGCCGCTGCAGTTGCCGGGAGCCATGGAGCCACGTGACCTT GAGGTCCACCGGGGAGAGGAGGGTGCATTTCGGAGGCTAGAAGTGGCACCTGGAGGGGCT GGCCCTGGGTGTGATCATTGAGAGGAGGGAGGTGGAAAAAGATCTGGAAGATGCCCTTGG GAAGCAGAAGAAGGTGGGTGACCAGAGTGGGGTGCCCAGAGGGTAGGGCAGGGCAGACCA GAGGAGGGGGTGGGCTTGGCACCCCCGGGAAGGAGGGATGGGGCTCTGTGAAAGTGAGAG CTGTGTGGACGTGGAGCTTGTGAGTCTGACCAGGAAAGACAGAGGGTTCCAGACGGTGCG GGGGCCCCTTCAGTCTGGTTGTGTGGGGCAGGGTCCTCACCCCCAGGTGAGGGGGCCTTG TAGGGCAGATTCCTGGAAGACCCTCAAGACGCAGGAGCGGAGGCTGCTGGCTGGATGGGG ATGGAGCCGAGAGCTGAGCGGGCAGCCCAGGCCTGAAGGACAGCACAGGGGCCTCTGTGA GGCCAGGAGGGGCTGGAGTGCAACACCCCCTGTGACCCAGGTCTGGTGTGTGACGCGTCA GGCCCCACGGCACCGCAGGCTGGCTGGCTCCCCAGAAGGCCTGTGGTCTCCATGGCCGCA GCGCATTCCGGGGACAGGGCAGAGTGGAGTCAGCAGAGGGAGGAGGCGTGTGGGGCGTCC AGGGATCAAGGGGTCTCTGGGCCTTGCTCCCTTCCCCAGCAGCTGTGAGGATGGTGGGGG CTGCTGTCTGCCCAGGACTGCAAGCGTCAGGCACAGCAGCTGCTGTTAACAGTCAAGGAA TGTTCGGGTCAGTTTGAGAACTTCAGGGCCCAATGGCAGAGCCCCGGCAGAAAGACTCAG GGCAGATGGTGGTTGTCAGCCGGGAGGGGGCACGGAGCCCTGGGGGTGGTCAGGCCCACG TGGCCTTGGGACGAGAGCGAAGAGGTGGGATCGGCTGCGGGAGACAGGGAAGTGGGTGAC AAGGAGGCTCAGGGGCTACAGCAAAGGCCCCGGAGGCTTTTCCACACCCGAGTCCGTCCT CGGCCATGCCAGCCAGGTCAGGGGCTCAGTCCTGTGGGCCACCACAGCCGGCCGCACAGG CAGGGAAGGTGAAGCTCCACGGAGCACCCTGGTGGACAGCGGTGCTGTGGGGGCCATGGA CCAGAAGGCGGAGCCCATGCTGTGGGCTGGGTGGGGTGGCAGCTGCCAGTTCAAAGTCTG TCTTTTGTTTATTTACTTCATAAAATACTCCAGGTGTTTTGTTAGAAATTATTCTTGGCC GGGCACGGTGGCTCACATCTGTAATCCCAGCACTTTGGGAGGCCTAGGTGGGCAGATCCT GAGGTCAGGAGTCGAGACCAGCCTGGCCAACGTGGTGAAACCCCCGTCTCTACTAAAAAT ACAAAAAATTAGCTGGGTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAGG CGGAGCTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGA TTCCGTCTCACACACACACACAAAAAATTAGTTGGGTGTGGTGGTGCACGCCTGTAGTCC CAGCTACATGGGAGGCTGAGACAGAATTGCTTGAATCCAGGAGGCAGAAGTTGCAGTGAG CTGAGATCACACCACTGCACTCCAGCCTGGTGACAGAGCAAGACTTTTTCTCAAAAAAAA AAAAGCAAAGAAAAGAAATTACTGTCTTAGTGTTGATAAATCTGCCTTTATACATACCAA TAGTTGTGCACACTGAGAGAAGTAGGCAGTTTTGGATCTGAAACTGGCCTGGTGACACCG CGGGTGCAGCAGGCGGGCAGATGCGGGCACAGGAGGGAGCTTCCCACACTGTTCAGGTCA CCAGAGCCTGCGCTTCTGTGGTTGGTTTTGATGAGGACTCGTATTTCAGCTCCTGTCTCT CCTTGTCAGAGGCCGTGTGAGGTGCGTATTGCGGACCGCCGGCCGCGCTGTGAGGGGTGT ACATGTGGAGCCGTGACAATCGTGGGAAGTTCTGTTTCCAGCTTTAAGCTTTCGTTTATA TTTCTGCATATTAAGAAATGATAAATTAAGACCTAATGAGAAGTTGTGGACTAGACGTGG GGTGTGTAGGCTGCTGGGAGGAGGGGCAGCGGCCCTGAGGGGTTGTGGGGCCCATGGGAC CATCTGACCCAGTGCATGGCGGAGCCGTGTCCACGTGAGGAGGGAGTAGGAACGGGCTCT GCGCTGTGGCTCCGTGGGCTGCCGAGGGCTGCTGTGGGCTCTGCGCTGTGGCTCCGTGGG CTGCCGAAGGCTGCTGTGGGCTCTGCGCTGTGGCTGTGTGGGCTGCCGAGGGCTGCTGTG GGCTCTGCGCTGTGGCTGTGTGGGCTGCCGAGGGCTGCTGTGGGCTCTGCGCTGTGGCTG TGTGGGCTGCCGAGGGCTGCTGTGGGCTCTGTGCTGTGGCTGTGTGGGCTGCAGAGGGCT GCTGTGGGTTCTGCTCTTATTTGCCCAGGGGAAACCCGAGTCGCTGCCCCTCCTGTCCAG CCTCAGCGCTCGTCCCCGGGTCCCCCAGCAGGTGACCACAGATGATGACGGAGCCTCCTG GAACCGCCTCAGTTTCCCCAGCTGGCCCCTCACTGGCCTCCCCATTTCAGGAGCCCCAGG GCCACTCTCCGCCAGGCTCTCTGTGTCTCCGATTAACCCTCAGGTCGTCCCAGCCTCTTC CGAGCCATGGTTAGGATCGGCCCCGTCCACCGTGTGTCCATGGAAGTGAAACAGGCCACC AGCAGTGGGCAGCCGCGGGCGGGATGGGCTGTGGGGCAGAGGCTGGCGGGCAGGAATGGT CTCGTGGGTGCGCACCTGGCCTGTGTGGCGCTGCGGCCGTGGCTTCTGCATGCCAGGGTC AGCAGCCATCTTGTCGGGTTTTTAATGTGCATTTCCCAGTTCACTGATACAGTTGAGCAT TTAAAACATGCTTGTTTGAAATTTCTCTTTTGTGAAGCTCTCTGTTGGCTAGAGTGGGGC TGGCAAACCCTGTGAGGGAGCAGATGGTGAATATCGTGCGGCCCCAGGCCTCCCTCCAAC GAGCAGCGCTGTGTGCTGGGAGCAGGCCCTGCGGGGGCCAGCAAACCCGCTCACACAGCC CACGGGGCACAGCCGGGCCACGATGGCCAGGCCCTGGTCTAGGTTGTGGCCCTGGAGGCA CTGCCGAAATTTCCCTCAGGCCTTGGCTTTTTTTCTCCATGGTGCTTTTGAATAACTCAG GGTGCTTATCTTTGACTTTGTCATTTCCTTCATGGTCAGTTTTGTTTTCTGTCTCGTAAA TCTTCTCCTCATCCACGATCATGACGATACCCTCCTTAGCAACCTCCAAAGGTTCACGGT CGCCTTTTCCATTGTCCTCACCCACCCGGCCCTGGTTATTTTTGGGGTGGGATGGTGCAA TACAAGCTGACAGTTTGGCTTTTTTTTTTCTAATTTCACCACAGGAATGATGTTTATGGT GTATGTTTTTAATTCTAAGATACACACTAAAATTCACCAGTTTTATTGTGCAGTTTGGGG ACTTTTCACCCCCTGTCCAGTTTCATGGACTTGCCGGCAGTGCTGGCCCAGAGCTCGGTC CCCGCAGGCCTCCCTCAGGTCCCTCTGTGGCCAGTCCCTGCCTTGCCTGGACTGTGTGTG CCTGTGTCCTCCCACCAGACTTGCCGTTGTTCTGGAATTGAGTGGCGTGTGGGAACGTGT GTGCGCTCCTGCGTCTGCCCCTCTCCCCTGTGGGATCGTGGGCACCTGCGTTGCTCACTC TCACTGCCGAGCCGCATCTGCGTGGGGAGGGGTTACGCTGTGTTTATCATCCGCCTTCTG ATGGACTAACTAGGTGGTTGTTTCCAGTTTGGGGCTGTTAGGAAAAGGGCTGCTTTGAAC ATTGTTGTATAAGACTTTGAGAGGATGTGTGTGTTAGCGAGCGTCTTTTTTTTTTTTTTT TTTTTTTTTTGAGATGGAGTTTCAGTCTTATTCCCCAGGCTGGAGTGCAAGGCGCGATCT CGGCTCACTGCAACCTCCGCCTCCCGGGTTCAGGCGATTCTCCTGCCTCAGCCTCTCGAA CAGCTGGGAGTACAGGCACCTGCCATTACACCTGGCTAATTTTTTGTATTTTTAGTAGAG ACAGAGCTTCACCATGTTAGCCAGGATGGTCTCCATCTCCTGACCTCATGATCTGCCAGC CTCGGCCTCTCAAAGTGCTGGGATTACAAGCATGAGCCACTATGCTTGGCTGAGTTTTGT TTTTTTTAAATCATGAATGGACAATTATTTTGTCAAATGATTTTTATGCACCTGCTGGGA AGATCATGTGATTTTTCTCCTTGTATCTTTTGTCATAAATTGTATCTTTTTCCCATAGGC ATTAAGCCCACGTTGTTTTCTAGGACTCTGAGTTTGTCAAGAATGATTATCTTTTTGTAT ATTGCTTAAAAAGGATGACTAACCGTTTTCTTTGGATTTTCACCTCTGTGTTTCCTGGTG AGGTTAACGTTGAGTTCTTTCCGTCTGCCATGGTCAGTGCCTGGTTTTGTCAGGCTCATA GTGTGAGTTGGAAAAAGGCTCCTTTTAGTTCTCTGAGAAGAGTATGAGACTGAATTATTT GTGCCCTGAGCGTCTGGTGAAACCACCTGCATCCCTCCGGGGCCTGATGCTGTCTTGGAA GGGACTTTCTGACCATTGACCTGGCTCCCTGTAGGTTCTGGAACTTCCTGGGTTTTCTCT GCTAGTCTCAATGCTGGTGAATTACTGTTCTAGGAACTTAGCAGTTTCACGTAAACTTTC CATTTTATTAGGGTCAAGTTCATCATATCTTGTCCGTGCTCGGACGTCACCTGCTTTAGG TGCACCCGGTTTAATAGTGCACGGCCAGCTCCCCCGAATCCATGGGTCCAGTCAACACAG ATTGAAAATGTTTGGGAACCAAAACAATAACAAATAACAGTACAACAATAACAATAATGC ACATCTTAAAAATACAGTAGAACAACCATTGACATAGTGTTTACAGCATGTTAAGTGTCG TAAGTAATCTGGGGATGGCGTAGAGTGCGTGGGGGGTGGCGTGCACAGCGTGTTAAGTGT CGTAAGTAATCTGGGGATGGCGTAGAGTGCGTGGGGGGTGGCGTGCACAGCGTGTTAAGT GTCGTAAGTAATCTGGGGATGGCGTAGAGCGCGTTGGGGGGCAGCGTGCATAGCTTCTGT GCAGACTCGACACCACTTCATGTCCGGGACTTGAGCACCTGTGGATTTTGGTATCAGCGG CGTCCTGGAACTAGTCCCCCACGGATACCAAGGGATGGCTGTGTGTCACCTTCTAACATA GTAAATAATTGACCTGTTTGTTAGTTATTGTCTGTCTTCCTTCATTAGAATGCTGGCTCC AAGGTCTGTGTCTGTGTTTTCACTGAAGTCTGAGAACTCCTGTCAGGAGCCGCCAGCTGT ACCAGCCAACACAGGAGCCACTGGCCACAGTTTAACTAAAATTAAATACAATTAAAAATT CGTTCGGTTGGCCGGGTGTGGTGGCTCACGCCTGTATTCCCAGCACTCTGGGAGGCCGAG GTGGGTGAATCACTGGAGGCCAGGAGTTCGAGACCAGCCTGGGCAACATGGTGAAACCCC ATCTCTACTAAAAATATAAAAGTTAACTGGGCGTGGTGGCGGACGTCTATAATCCCAGCT ACTCGTGAGGCTGAGGCACAAGAATTGCTTGAATCTGGAAAGTGGAGGTTACAGTGAGCC GAGATTGCACCACTGCACTCCGGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAA AAAAAAAAAAAAAAAAAAAAACTGGGCTGGGCACGGTGGCTCACACCTGTAATCTCAGCA CTTTGGGAGGCTGAGGCGGGAGGATCACTTGACCCCAGTAGTTCACGGCCAGCCTGGATA ACAGACTGAGACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGTGCATG CTTGTAATCCAAGCTACTCAGGAGGCTGAAGTGGGAGGATTGCTCAAGCCCAGGAGGTCA AGGCTGTAGTGAGCCAAGATCGTGCCACTGCACTGCAGCCTGGGTGGCAGAGCAAGATCC TGTCTCAAAAAAAAAAAAAGAAATAATAATAATTATAATGAGATCCTTCAGTCCCACAAG CCACAGTTCAGGTGCTCCACGCCATGTGTGGTCAGCAGCTGTGCTGTTGGGTAGTGGAGA TGTGGAAGCCCCCAGTGTTGCAGAATATTCCGGAAGCCTGGCTTTGAGCCTGGCTTCATT CTCTTCATCTTGTTTCTCTTCTCCCTAACTCAAGTGCCTCAGACATGCCTGCTGATCTCC CCTTATATTTGCCTGGGAAGACTAACTCTACTCTTTCCCTTCTTCCTCCCTTTTTATGTA AAAGTTAACTGAGCTTCAAAGATTAGTTAATAAAAAGTGCAGTTATGGGAAACCGGAAGA GTAGAAATGATACAAACGGGGTAGAAAATGAAGAGCATGAAAGTATTTAATCTCTGTCAC TAAGCCACAGACACTGTACGTCATCCCAGGCCCCCACTTTCCCCAGTCTGACTCCAGCCA CCTGTTTCCCCAACTCACACAGGAACGTGTGGGAGGCCACCGAGGTTCCCGGGGAAGCAC TCCCAGCATGGCAGCCACCCTGATGCCCCATCCCAGACGCAGGGTCCCTACGTGGTCCCC TGGTCCCGGGTGGGGACTGTGTCCCTCCCCTGCCCCTCCCTCCCTGTCTGAGGCCCCAGG TGCCCTCCCTGTCCTCATCCCCACTGAGCCCAACACCAGGCTCAGTGCCCACGCCGGGGC CCTTGGTGCACGTCTGGTAGGCGCAGGCAGGTCTGTGACTGGGAGAGAACATGGTGCCCT GTGCACAGCAGCAGAATTGCGGGCATCTCTTGGCTGCGTCGTGGAGCCAGCCGTCACTGC CTTGCCTCTGAGGTCTTGCATTTGCCCAGATCACCCCTGAAATTCACCCCTCCTCTGGGG GGCTCCACAGACTCACATCCTGCCTTCTTGGGCCCAAAACAGCATGATGGGGCCCCCAGC TGCCCCCCCACCCCCGTGGGCCACGTGCCCACTCCTGCTGTCTCCGATGCCTTGGGCCTG GGCTCAGAGACGCCCGACAGGCACCGAGACCAGCCCGTGTCTCCCGGGTAGAGCCTGTTC TTCACGGTCCCTGTGAAGAACTTTTGGTTATTTTAAGCAAGGAACAGAGCAGTGTAACCG AGCCAGGCTTGGCACCGCGGGTGGGGTGGGGGTCGTCCGCCTCCGGCCCACGGGTAACCC TGTTGTGCTTTTTCTCCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAG GTAAGTGCGCGTAGGCCGACTGCCCTCTTCTTTCCGCACCTGTGAACTGCCGGACTCCGC CGGGACCACGCTTTGTGCATGTGGTCGGCGTTCCTTGCAGTGCCTCTGAAACGCAGGCTC TGAGGACAGGCTGGAGCCATGCGTGGGTCCTTAGCTTTTCTCCCGGTCAGTACTTCTGAT TGACCCCATTCCGCCCTTTGCTCGGTAGGGCTTGGTTGCAAGTTCCAGTAGGAATGGCGG AGTTGTGGCAGTCACACATCCATGACGCGAAGTGAACTAACAGGTGCCGTTTCTGTGCTA GAAAATGGAAAAAGAGCCAGGGCCGGAAGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGC CAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGAGGGACG GACACGCGGACGTCTAGCGGAGGTGAGGCCCACGCCCCCCGACCCCGGGGGTCCTGCTGA CTCCTTGCCCTGCCCTGTTGCTGGTTGTGGCGAGGGCCGGCGATCATTAGGAGCCAGCTG GTCAGGACACGATGCAGTGTTCACGGTTCACTGCCGAGTTTTCCTGGCCCCTCCTGTGAG AGTCCAAGGTCCAGCCAGCTGTGGGGGTCCCAGGCCTCGATGGCAGTGCGGGGTGCAGAG GGCTGGTCTCCTTCCGTCACTGGTTCACTTGGGTTCCCGGCGTGTCGCTGAGGAGCAGTG CTGCTTGGGGGCCGAGCCTGGGGCCTCAGCCCAGTGAGTTGTGAGGCGGTCGGCTAGCAT CCTGCAGGGAGGTCCTCAGGGGCGCAGGGCAGGGCTATCTCTCCCCTCCCGGGTGCTCTG TCCCCTCGTGGGTGGGCGTGGCCCTCAGGGGTGTAGGGCGGGGCTCCCCCTCCCGTCGTG GGTGGGCGTGGTCCTCGGGCATAGGGCGGGGCTCCCCTCCCCTCGTGGGTGGGCGTGGTC CTCAGGGGCGTAGGGCGGGGCTCCCCCGCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCG TAGGGCGGGGCTCCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGG CTCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCCC TCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCCCTCGTGGGTGGG CGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCCTCCCCTCGTGGGTGGGCGTGGTCCTC AGGGGCGTAGGGCGGGGCTCCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAG GGCGGGGCTCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCT CCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCCCTCGT GGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCCCTCGTGAGTGGGCGTG GTCCTCAGGTTGGTAAGGCGGGGCTCCCCTCCCCTCGTGGGTGGGCGTGGTCCTTAGGGG CGTAGGGTGGGGCTCCCCCTCCCCTCCCGAGTGGGCGTGGTCGTCAGGGCGCGGGGTGGG GCTCCCCCTCACCTCCCTTCCCTCCCTACCCTCCCCTCCCCTTCCCTCCTCCCCTCCCTT CCCTTCCCCTCCCCTCCCTTCTCCTTCCCCTCCCTCTCCCTTCCTGGGCAGGCTCCCGTG TCCTCAGTATGCATCAGGTCTCCCGAACCTCACAGCCCCGCAGGGAGGAGGAGAAGGGGA GGATTTGACTTTGGAAGTCTCTGTGACCAGGTGAGGACCGCAAGCGTAAAGGTGGTGGCA GAGTGGTCGGGGACAGGCCTCACCCACAAACATGTGGCCCCTGGATGAGCCCAGCTCTCA GCTGCTTCGTGGGACTGCAGCTGGACGCCCAGGCCCGCGCCTGCAGCAGGCGATGTGGGG CTCAGCAGAGAGCTCCAGGCTGGGCCTCTTGGTGGCGGTGATGACGGAAGTGGTGTCACG CATGCAGCAGTTTGGGTCGCGGCTTTCCGTCCCCACTGAGGGAAACTCGTGCCTGCTGCT CCCCTGGTGAAAGGTGTGGGGAGCGAAGTCCCAGTAGTGGGGTGCACCTGGCCACCCTGA GTCCCCACCAGCCTCCGCACGCGGAGCGGCCCTGCTCTCTTGCCTCAAGCACAGAAGCAA ATCACCAGGCTCTGCCTGCCGTCGTGCGGTGACATCGGGGGTCACCTCCCCGAAGGCGCA GGTCTGGTGGGCGAGCAGAGCGGCTGCGGCAGCTGTCAAGGCAGGGCCTCTGCCAGCCAC TGTGGCCTGGCATTGTGCCCACCCTGTGAGGGTAGGGTGGGGCCCCTGCCGCGTGCTGCC TCCGCCCCTGCCCCGTGCTGCCTCCGCCCCTGCCCCGTGCTGCCTCAGGCTCTGGGAGAC ACAGCCTCAGGAGACACCGTGGAAGCCGCGCCGGCCCCACAAGTGAATGGGGAGGAAGGG GTGTGAGCATACAGCCCAGACTCTAAACTGGGCCCAAGGGTCGCGCTGTGAGCCGCAGAG GGTCCAGGTGCCCAGAGCCTGCCCATCCTCATCCCACCCGGCAGCTCTGCCTTCGCGGGC TCCTCCTGCTCCTTCCGCTTTCACAGAAGACAGACAGCTCGGGGATCCTGCCTCTCTGCA GCTTTATGGACCCTCCTCAGTCCTCACTGCAGGAGGAGAGGAGGGGGTGTTGGGCACAGA GAGAAGCCAGTGCGGGGGAGCCGGGGGCTTTTGAAAAGGTGGGCTTGTCCCAGTGCACGC AGACACTGGATTGCTGACCGTGCCCTGCACATGGGAGCCTGGGACCCCGTGAGCCCAAGA GGCTCCTGCCACCCAGGCCTCAGGGCCTGCACTGTCCTCCCTGGGGGCGGCTGTCAGAGC TCAGCCAAGGATGAAAGGCATGGAAGAGTTTCAGGTGTTAATTAATCGCGTTTTCTCTTG TAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACC TGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACC TGTACGTGCCCTGCCCGCGCCACCCAGGGAGGGCGCGCCCTTCCCAGCTCTGTGCTCTTC AGAACCTTGGCTTTTGTGTTACCACACGCTTTTAGCTCAAGCCCGACAAAAGCAGGAACC AGGACCAGGGGCAGAGACGATCTTGAAGATAAGTCAGAAAAGTCATTTCACGCTAAAGGT CCTGTGGGTGGTGTCAGAGCAGATGAGGCCTCGCTTAGGAGAGCGAAACACAGGAGAGAC CCCACATTCCTCCCACGGAGCAGCAAGGCCAGTAGCCGCTGTGACAGTGCTCACTGCTGG CAGTTTCCAAATCTCCAGAGGAGTTCCTTAGATCCTTCAAAGGGGAACCTTCCAGTGTGT TCTTCACACCTGATGTGCGTCCTCACACCTGATGAGTCTGTGCTTTGGTGTTAGAGGACT CACACCTGGGGCTGGACCTGAGTGTTTTTCTAAGTGTGGCTACCGCTGACGGGCAGGTGC CATCCATCAGGCTGAGGCTCGGCTCTTATGCTAACCTGAGGCCCCATGGCTGGCGGCCCT GCTGGTGTGGACGACCGCTGTGTGCGTCTCTTGATGGCTGGGGAGCATTTTGTTTAAACA GGATCTTTAAAATGAAGTGTACGCTTATAATACAAGTGATGCTTGTGTATTTCTCACTTT AGGAAATAAAATATTTGCCAATTTGATAGAATTTTGACTTTAACGTTAATCGTATTTTTA GATATTGGTTAGCATATTTTATGTTAGGTTATTTTCATTTGATTTTATCTAGTTGTACGT AGAAGATACTGTCATCTTTTAGGACAAAGTATTGTAAAATTATCTGTTTTAGCCCATGTT CTGATGACCCACAGCTCTGTCACCTTTGAGCATCATCTCCCCATTCTAAGTTTTTTTCCC ACTTAATTCCTAACCCTGCCTCTTTGAGGAAGCCCATTGACGGGGCAATTAAAACCTTCT CATTGCTCCTGAGACCAGAACGGCAAGATGTTTCCTTTCAGAAGCTGAGAGCCACAAGGA GGACAGCAGTGAGCATCTGCACAGAAACGAGCTCAGAGACGCCCGTGTTCAGTGGAGCAC GCCGATGGGGTGGGCGCCCTGGCTCTAGACGCTCTCCTAACACACCTGTGCTTTGATGAC AGTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAG GATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGGTGAGTGTGGGCCTTCCCAGG CCACAGTACGTGGGGTGAGTGCCCCTGGGCGTCTCTGTGTGTGGGCCTTCCCAGGCCATT AGCGCTGTACTCCCATCCTGCCTTGGCAGCAGCCTCTCCTGACCAAGGGCACCCCAGGAG CTGCACACGAAGAACCTGGGTCCAGCGCTCACCAGGCCATCCTGCCAGGCCTGCCCAGGC TGTGCCTGCACATACATTTCCATCAATACTTAGGTAGGCCGGGCGCAGGGGCTCATGCCT ATAATCCCAGCACTTTGGGAGGCCGACACAGGCAGATCACCTGAGGTCAGGAGTTTGAGA CCAGCCTGACCAACGTGGAGAAACCCCATCTCTACTAAAAGTACAAAATTAGCTGGGTAT GGTGGTGCATGCCTATAATCCCATCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAAC CCAGGAGGCCGAGGTTGCAGTAAGCGGAGATTGCGCCGTTGCACTCCAGCCTGGCGACAG AGCGAGACTCTGTCTCAAAGAGAAAGAAAAAATACTTAGTCAAGTTAAATTGTTGGAGAG CCCTCAAGACCAAGTTGAATCTCATGAGTTTTACGCAGAATTTGCTGAAGTTAAATTTGA TGTGAGCCGGCCCTTGGATACCCCTTTCACCTTTCTGCCATGGAGCAGATGGTCCTGGGG CCCTGGCCCTGCTGCCCCTGACACATGGCCAAGGTCTTTCTCCCTGCGCTGTGCTCTTCT GCCCAGGGTCACAGCGAGCCTGGACTCACCCCTGGGCCAGCCACCATTTCTGGAGAAGGC AACTCTTGCCTGGACGTCAGCAGGAGGCCAAGGGGCCAGCCAGGTGGAGCGTGTGGTTCT CACACAGATTTGGGAGGTCGTTCAGATTTGGGGGGTTGCTCCAAAGGAAGGGAAATGCTC CCCGTACCATGAGGGTAGTAGAGATAATTCTGAAGACACATTTTGAAGGAGGAAAGGCAG ATGTGTTTGTTTTTCCCTTTTATTATTATTATTTTTCTTAATTTTATTTATTTTTCTTGA GATGGAGTCTTGCTCTGTCGCCAGGCTGGAGTGCAATGGCGCCATCTCAGCTCACCGCAA CCTCCACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTAC AGGCGCATGTCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCA TGTTGGCCAGGCTGGTTTCAAACTCCTGATCTCAGGTCATCTGCCCGCCTCAGTCTCCCC AAATGCTAGGATTACAGGTGTGAGCCACCACACCCGGCCCTCACAGACTTTTCTTTACAT TATTTGGAAACATTCTAGAAAAGCCTCTGTTCATTGGAAATCCCACAAAGACCAGGAGAC CCCAGGAAGCACTTGGTGGGAGGGGCAGGGACAGTGTCCCCTGAGCGCATAGGATGCAGG GAACCCGGGGTGTCCGCAGGGACGGTGTCCCCTGAGCGCATAGGATGCAGGGAACCTGGG GTGTCCGCAGGGACGGTGTCCCCTGAGCGCACAGGATGCAGGGAACCTGGGGTGTCCGCA GGGACGGTGTCCCCTGAGCACACAGGATGCAGGGAACCCGTGGTGTCCACAGGGACGGTG TCTCCTGAGCGCACAGGATGCAGGGAACCCGGGGTGTCCGCAGGGACGGTGTCCCCTGAG CGCACGGGACGCGGGGAACCCGGGGTGTCCGCAGGGACGGTGTCCCCTGAGCGCACGGGA CGCGGGAAACCTGGGGTGTCTGCAGGGACAGTGTCGCGGGGAACCTGGGGTGTCTGCAGG GGCGGTGTCCCCTGAGCGCACGGGACGCGGGGAACCTGGGGTGTCTGCAGGGACGGTGTC CCCTGAGCGCACGGGACGCGGGGAACCTGGGGTGTCTGCAGGGACGGTGTCCCCTGAGCG CACGGGACGCGGGGAACCTGGGGTGTCTGCAGGGACGGTGTCCCCTGAGCGCACGGGACG CGGGGAACCTGGGGTGTCTGCAGGGACGGTGTCCCCTGAGCGCACGGGACGCGGGGAACC TGGGGTGTCTGCAGGGACGGTGTCCCCTGAGCGCACGGGACGCGGGGAACCTGGGGTGTC TGCAGGGACGGTGTCCCCTGAGCGCACGGGACGTGGGGAATCTGGGGTGTCCGGCAGACA GAAGCACGGGTTCCCAGAAGAGCCTTCTCTGTCATTATTTGAAATGTTTGAAGCAGCCAG AGCCCAAGTTAAATGACGCGTTAATTCAGCTCATACATGGCTTTTGGTGACACATTTTTT CATGTGTAAACTAGAAGTAAAATTCCAACAAAGCTCCAGACTGGTGATTCTGAACTTTGA TATTGTTAAATGGAAAGTGTACAAGAATTATAGAATTAACATTTCCAGCTAACTCCACCT TTCTGTTCTTTTGCCAGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCA GGCCTCCAAGAAGGTGAGTGTCTGACTGTCTTGCTGATCCCTGAGGTCCCAGCCTGGCCT CTGCAGCCCCTGCTCTCCTGGAAGTTTGGTTCTCGGATGGGAGGCCCCTTTCCTTTTGGC CGAATCACCGTCTTCTCATCCCTGCTCTCAGCCCAACTTCATCTCCTTGGCTGGTCTCTT CTTTCGTCTAAGATGCGTAGACATCTTTTTACCCCTTATGTGTATTCATTCAGCAAGTAT GGATCGCATGTTTAGCACATGGGACCCCCAGGGCTCAACGCAGCTCCTGCCCCTCCCAGG ACCCTGCCTTCTTCCTGGGCCCCACCTCCTGTCCCAGGCCTGCCTCCCCTCATCCCACAG CGCCAGCTTCCCCACAACAGAGGAGCAGCACGTTGGCATAGCGGGTAGCTGGTGTTTCTA GAAAAACTTCACCATAAAGTCAAATTTCATTTAGAATTAAAAGAAATACCAAGTAGTACA AATACCCTGAAAGTGGAAATCGGTTGCTTGGGGATCGCTCAGCTGAAAGCTCCCCAGCTC CCGACACTCTCACGGTGGTGGCCCTCCGCTGGCGACCGGCAAGGAGGCCAAGGAGGGGCC AGGTCAGCGCCAGGTGGGCTGTCCTGGTATTCTGCTCATCAGACCTTTCAAAGGCAGATA GAGAAGCTGAGAATTCACTTGGGCTGGTTCTCACTGTATCTCAGAAGAGGGTTGGAATTC AAAACACAGCTGAATATGCCAGATCCGTAGAAACCGTATCTCGCTTTAATGCGTGACCCA GAGAATCATACTGTTAGAGGCTTCTTCCCTACTCACAGAGTTCATTCATGCAGGAAGAAT TTAGATTTCCTGAGTAAACGTAGATAGAAACAATTAGTCTTTTAATATCTGAAAGTTTTT TAGTCCTGAGAAAAGGCAAAGGATACATTCGAGTTAAATGCTGACACCTTAAGAAACGTT TGCACCGAGTGTTTCAGACGCGTAGCAGTGGGCGGGATCGGGGCGGGACCCCAAGTTTTG TGACCCCCGCCAGTGCTGACACTTTAAGAAACGTTTGTGGCCGGGTGCAGTGGCTCACGC CTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATCAGGTCAAGAGTTTGAGA CCAGCCAGACCAACATAGTGAAACCCTGTCTCTACCAAAAATACAAAAAAAAAAAAAAAA TTAGTCGGGCGTGGTGTCAGGTGCCTGTAATCCCAGCTACTCAGCAGGCTGAGGCAGGAG AATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCGCCACTGCACTCCA GGCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAATAAATAAATAAATAAAGTGTGCAC TGGAGCGTTTCAAACGCTTAGCAGTGGGCGGGATCGGGGCAGGAACCTCGAGTTTTGTGA CCACCACCCCCCGCCAGCAGTTTCTAGGCGTGGCCGTCCTTGCTGCACCTGCTGCTCCCT CAGCCTCACCCCGTGGCCTTTGATCTGTAAAGGCTGCAGTACGTATCCCCAAAAGATAAG GGTTCTTCTTAAAGCTCATAACCACAATACCTTGATAATGTTTAGGAAAATAGTAGAGAT TCCTTAATACCAAATAGCCACTCAGTGCTGACATTTCTAGTTGTCTCATAAATGCGGTGC TTTTTGGTTGTTGTTTATTTCTTTATTTATTTTGAGACCTGGTCTCTGCTGCCCAGGCTG GAGTTCAGTGGTGCTATCACAGCTCACTGTAGCCTCAACCTCCCGGGCTCCAGTGATTCT CCCACCTCAGCCTGCCAGGTAGCTGGAACTACAGGCAAGCACCTCCATCCTGGCTAATTT TTTGTAGGGATAGGGTTTTGCTGTGTTGCCCAGGCTGGTCTTGAACTCCTGGGCTCAAGC AGTCCTCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCCCCACACCCAG CCTGTTTTTGTTTATTCCAATCAGGATCCAGAGAATACCACTGACTCACGGGCCTCCTTC TGGTTCCTGCCTCTGCCTTCCCATTGTCCTGGGTTGTCCTGCGGCAGTGGACCTGGGTGC GTTCCACCCGTGTTTTTGGGAAGCCCGCTTCTGGGCATCCATCAGGGCAGGTGTCGTCCA TGTGCTGAGCCGGGTGGCACTGAGATCTGCATGCCACCTCCGTTCCATCGCTCGTCTCCA CGTGTTAGTTGGAGTGTGCGTCCAGCCTGGAGCAGGTTGTATGTTCTCGTCCACCTCAGC ACGCTCTTGTCCGGTGTGGACGCTGCCAACTCCACTCTACGTTGAAGAAGTCGAGAGGCA AGAGGTTCCGGAGTGCTCCAGATTGACACCCCCAGGGCACGGTGGCCCCGAGCCGCCTCC CTGACCAGCTCCTGTCTCTGGCCACCATATTTTCCGTTGAGTCAATATTCTTTTTCTTGT TGTTTCTCAAGCTTTCAGTCATTTGTGGCTCTTTAGCAGGAGGATTCTAACTTTAAAACT ATTAGCAGTGCACCTATTTTCTTGATGGAGGCTACTTGCAATTTGTTTAGTTTTATCTGT GGTGCAGACAATTGCAAACCTCATTTCTCCGACCAGAGGCCTCTTCCTGAAACGCGCGTT AGCTGCGAGGATGCAGTGGTGAGGCGAGGTGTCAGCCCTTGAGGGTCCAGGTGTCTGTTT TGGAGGAGACGCCAACACGGTCCTGCCCCTCCCACCTGGACTCCGGGCAGGCCCTCAACG CTGTCCCCGCACCCCCACATGGTGGGGGCTTGCTGGAAGAGAGTTCCCTGCTAGATCAGA GGTGGGGTTAGGTTTTTAGTGGTTTGTTGTTTCTTTTTGTTTTTATAAATTATTTTAGAA ACCTGTCTTCGTAGAGGCAACATGTTTAAAACATTTATCAAAGTGTCCATTCTCAGTCTC AGCCCACTCTGGGCTCTTTCACTCGGTGGGCGTGTCATGGTCTTTGGTGTGCCAGGCTCC TGTCCGTTCCTGGTGAGGGCTGTGGGGCTCACGCACTCACCAGTCCTCTTTCCATGGATC CTGAACATGCCTGTCACCTCTTGCTTTAGAAACGTGGGGGCCGGACACAGTGTCTCATGC CTGTAACCCTAGCACTGTGGGAGGCCGAGGCAGGAGGATCCCATGAGCTAAGAATGTTTC TTTACATTTTTAAATAGTTGGAAAAAATCAAAAGCAGCGTATTTTATGATGTGATAATTT AAGAATTGAAATTTCATGGTGCGTAGCCTGGTTGGAACCAGCCCCACTGGCTCAGCTGTG GTCGCCTTCACCCGTAAGCCCGTCCGTGGTGCAGCTGAGTGTGTGCCAGGAGTGTGCTGC CTGCCTGCCGGTGGCTTTGGGCAGCCCTCTGCACCGTGGCTGGAACTCATCGTCACTGCA TTGGGACGTTTTCATGACGACGTCAGAACGAGGAAAGGAGAAAAGGGGACTTTCAGGGCT GCACTTCGAAGCCGCAGTGAACTCTGGATTATTTTGTTGTTGAACTGTCATTGTTGATGG CAAAGCACCGACTTTCTCATCCGTCATACTGTAGCTATGCTGAGAGCAAACAGCCGACGA TGGAGTCACTGACTCAACACCAGCAATATCCCCACTCACAGGAAAGCAGTATTTAGACAC CAGCAATATTCCCTACTCACAGGAAAGCAGTGTTTACAAAATGCTGAAAATTTAAAATGG AATGTCTCATCACAGCAGAATTTCTTCTCAGAAGTGAAAATGAAGATATGGCTGTAGTCA GAATAAGCTTCCAATTGGCTGATTCGTTAGCGTTATGCCAACAGTGAGCTCCTCAGATCA GGCTGGACTGCCGCAGCTCAAGAGCAATGTCCAGAGACAGTGAGCTCTTATTTATTTATT TATTCAATCATTTTTGAGACGGAGTTTTGCTCTTGTTGCCCAGGCTGAGTGCAGTGGCAC GATCTCAGCTCACTGCAACCTCCGCCTCCCAGGTTCACACAGTTGTCCTGTCTCAGCCTC CTGAGTAGCTGGGATTACAGGCAGGTGCCACCATGCCTGGCTAATTTTTTGTATTTTTAG TAGAGACGGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCATGATCC GCCCGCCTCAGCCTCCCACAGTGCTGGGATGACAGGTGTGAGCCACCGCGCCCGGCCCCA ATAAATGTTTCAGTGCCTGTATACACCTGACACTGAGTGCTGCTATTTTTAATCCTTCTT TATTCTTACAGGTGAAAATTAAAGAAATGGGAACTAGAGCCAAGGGTCAGGGTCTGAAGC TGAGTTGCTTTCCACTGTGTCCGTGGGGCTCTCTCCTTTGCACGGACCTATGTGGCCTGT TGTTCCCGTCACGGCTCTTCTGCAGACTGATGGGAACAGCCTCCTGCTGTCAGCCCCTGT CTTGCAGGCCTCCATTCCAGCTGCTGGGATGTGATTATTTAAGGGAAACATTTTCTTTCA AGCTGCTCTCAGATTCTCCAGGCTAATCTTTCAGCATTTCCCTTGTGAGGCTCCAGCACT CCATCCACCTGCGGCCGGCCCCACCTATCCCCTTGGCTCTCAGGGTCCCCTCCTCTCTCT GCCCAGGCTCTCGGGGTCCCCTCCTCTCTCTCTCCCCAGGCTCTCGGGGTCCCCTCCTCT CTCTGCCCAGGCTCTCAGGGTCCCCTCCTCTCTCCCCAGGCTCTCGGGGTCCCCTCCTCT CTCTGCCCAGGCTCACGGGGCATCCTCCTCTCTGTCCAAGCTCGTTGCCTCACGCGGGCA TTGGTCCCTGCACGGTTGGTGTTTGTGAGGCAGCTGTGTAGGTTGGGGTATGCCCAGAGC GTTTCCCTGGCCTGGCCGAGCTCATGGTATGTAGGGAGGAAATCGTGGATAAAAAGTTTG GTGAAGAATTCCTTGGTCACGTAGCACATACGTTACTTTTCAGAGTGATGTCTGGGTTGC GGTTTGAGCAGCTTTTTTCTAACCTTTCTTTGCTACCTACTGTGTGTTCCCGAGCAGTGA CCCACGTCGTCCACTGTGTCCCCTGGGTGTGAACTAAGGTCACCCTTAGGGGGCCTTTGC CGAGAGTCTGTTTGCTTTTCCCTGGAACCTGCGAGGTTCTGGCCAGCTCTTGCTGGCCAT CCCTGGAGGGTCAGGCCTCCTCTGGTCCGGCCAGAGGTGACCCAATGGCAGGTGTGGGTG AGGATGCTGCGGCCCGTCTGCCGCCGGGCAGTCTCCTCCCTGGAATTTGTGCCTGTGGCT GTGGCCACAGACACCAGGGGGCGCTCTTAACCCACTGCCAGGCAACGGGGTGCCAGAGCT CATAGCTGTGAGCAGCCCTCCCTGCAGGCTGTGGACTCAGGCGCCTGGGACACATGGTCC CCGGGGCTCTCGGGCCCTCGAGGGCTCTCTTGGGGTTCCTCAGTGGTGGCCTTGGGTACC TGTGAGCCGGCAGGATCTGCCACTGCGCAGGAGCGTGGGGGGAACCCAGTGGCAGGTTCA TCTCTGAGCTGCGGGTGTCCAGGCAGTCCACTGGCTCAGCCGTGAGGTCAGCAATGATGT CTGGCATGGCACTGCTGTGGCCACAGTGTTTATCAACCCCTGGTGACGGGTGGTTCTGCG CCATTGGACACTCACAGGCAGTGGCTGAGGTGGGGATGACAGTCCCGCACCTGGGTTTCC CAGGCCCCGTGCCTGTCCTAGGCCTGGAGCAGCCGGTCTGCGACTCAACGTCCCACGTGG GTTGGTGGGGCGGGTGCCCGGGGGGTGCGCTTCCCGCTGTGCTGAGCCCCCAAAACATCT CAGTCTTAATTTGCTGCTTTCTTATTAGTAGCCTTCAAACTTCATAATGCAAATCCCTAA TTTTCTTTATGTGATGTTTATGAACAGAAGTTTAATAGAATCCACTGCCTGTGAGATGAA AGACTGTGTGTTGATTTTCCGCAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAAT TGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAG ATTCCCATCGGAATGGTGAGTGCCCTGCGTGCCCATCCAGAAGCCCCGGGAATCCCCTGC ATGAGGCCTTTTCTTAAAGAGCTGGCGCTGTCTGCCGGCCCCTCCCACACGCACTCACGG GAGAACGTGGGGGAACCTGAGGGTGTGGGGCGGTTAGGGTTCAAGGCGTTCCTCCTCACT CCTGGTACCAGTGGGAACGTGGGCAGAGGGGAAAAGCCAGCAGGGGAGAGCAGGAGGGCC CCCCGAGAGTGTCTGGGGGGCAGAGGTCAGGGTTCAGAAGGCCTGTGGAAAGAGTAGTGG AAGGTGAACTTCCTGAGACTTCACTTGGCTTGCTTTACTGTAAAATGGCAAAATAATGGT TTGGTTTCTGTGTAAAGGGAATGGTATGTTGAAATCTGAGGGTATCACAACAAACGTTCA TGTCTTGAGGACATTTTATTTTCCTAATGGACCACACCAACTCTTAGGAAATGTTTAGGC TCCTCCGGGCGTCTGTGACAGTTGGAGGGTGGGAGGGGCCTGGCTCTGTCACCCCCACGG CTTTGCGGGTCCCAGGAAGCACAGCCATGAGGCGTGGTTAGGAAGCGAGTCTGGGAACCA AGCAGTCCTGTCAGAACCCTTTTACCTGAGGGGAAGTTTTCATTTTAAAAGCGGTGTTGA AACAGTGGATTTTTAGGAGAAGGCTTTCAGATCGAGGGGCTGATGTGGTCAGCACTGAGC AGCTCCGGGCGGGCCTGGCCATGTGGCCAGTGCGGAGCGTGTCTGTGTCCCACGCCGGCT CCGGCTGCCCCGTCTCTGTCTCCTGTGCTCCCCACGCCTGCACCCCACAGGCCCACACGC CCGTTCTGCATCCTGGGGAGACCCCTGCAGACACTTTGCGGACGGCTTTCCTTTGACGCT TACTCCGCTCCGGGGGTCCAGAGTCTCTTAATGGAGTGAATTTTTGACGGCATTTGGAGT ACAGTGTAGTTTTTTAAATGGCTTGACAGTTTGGATTTCATGGTGCGCTATGTTCTGTTT GTGCTAAAAGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAG CCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGGTGGGCGGGGCCCGGGGGTCG CTGCAGTGTTAGTGTTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTG CAGTGTTAGTGTTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAG TGTTAGTGTTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGT TAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAG TGCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGC TCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGGTCGCTGCAGTGTTAGTGCTC GCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGTTAGTGCTCGCC GTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGG AGGCGTGAGCAGGTGGGCGGGGCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGC GTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGTTCGCCGTGGAGGCGTG AGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGC AGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCGTGGAGGCGTGAGCAGG TGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCGTGGAGGCGTGAGCAGGTGG GCGGGGCCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCG GGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGG CCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCC GGGGGTCGCTGCAGTGTTAGTGCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGG GGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGT CGCTGCAGTGTTAGTGTTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGC TGCAGTGTTAGTGCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGC AGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGT GTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTT AGTGCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGTTAGT GCTCTCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCT CCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCC GTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCGTG GAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCGTGGAG GCGTGAGCAGGTGGGCGGGGCCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGC GTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTG AGCAGGTGGGCGGGGCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCA GGTGGGCGGGGCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTG GGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGC GGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGG GCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCC CGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGG GGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGG GTCGCTGCAGTGTTAGTGTTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTC GCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGTCGCTG CAGTGTTAGTGTTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAG TGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGT TAGTGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGTTAG TGCTCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGC TCGCCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCCGGGGTCGCTGCAGTGTTAGTGCTCG CCGTGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCTCCG TGGAGGCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGG AGGCGTGAGCAGGTGGGCGGGGCCCCGGGGGTCGCTGCAGTGTTAGTGTTCGCCGTGGAG GCGTGAGCAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCG TGAGCAGGTGGGCGGGGCCCGGGGTCGCTGCAGTGTTAGTGTTCGCCGTGGAGGCGTGAG CAGGTGGGCGGGGCCCGGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAG GTGGGCGGGGCCCCGGGGTCGCTGCAGTGTTAGTGCTCGCCGTGGAGGCGTGAGCAGGTG GGCGGGGCCCCGGGCCTCCGGGACACTCCTGTATTAGTGCTCCTGTAATAGTGCAGTCCT GGGAGCACCGAGGGAGGGCTCACACCAGAAACCTTCCCTGGGGATGAAGGGAAGCAGTGA CAGCCAGCACCCAAGGGCTGCTGTTTTCTTCCTCCCGACTTCTTCCTTTTTCTTTTTTTT TTTAATTACCAGAGGAACACGTGCTTAGGGTAAAGCATGGCAGATATAAAACATGGCAGG TCAGTGGCCGGCTCTGGCCTCAGCCCCATGGCCCACGTTTTGTGCCTTTTCCTCCGGGCG CGTCTCTGTGCTCCGTGAATGTTACGTGAAAGAAAGTAAAGCCTGGCAGTGTGTTGAAAG GAAAGTGAGAGTGAACGTCGAGGGCCTCTTCGTGTGTCATTTACTGTATTACCAGATGAA GACAGAAAAACTACACGGTCACAGAGATGCAGTAAAAGAATTTGATGAAATTCCATACCC ACGTCTAGAGAACTTTTTTTTTTTTTTGAGATGGAGTTTTGCTCTTGTCTGCCAGGCTGG AATGCGGTGGCACCATCCCGGCTCACTGCAGCCTCTGCCTCCTGGGTTCAAGCGATTCTC CTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCCGCTCCGTCTGGTTAACTT TTGTATTTTTAGTAGTGACAGGGTTTCACCACGTTGGCCAGGCTGGTCTCGAACTTCTGG CCCGCCTCAGCCTCCCAAAGTGCTGGGGTTACAGGCATGAGCCACCGCGCCCAGCCAAGT AACGGAACCTTAATTTTTTAGTTTACATTTACACGTTGTTTAAAACGTTCAGTGAGCATT ACAGAAATAGACACGTGTGTCCAACGTGGGATGTGATGGCGTTGCCTTGTGGGTCAGTAG AGAAGAGCGGCCAGTTCAGAGAAGGGGTCCGGAGGGGCAGGAAGCGAGGAAATCACCTTC TTCTTTCATGACCCCGGTTTCACTGCCATGCCTGGTTTCCGATGTTGACGTACCTGGTGC TTCCTCTGTTGGTGGCTTGGCGGCTCTCCTGGAACCACGCTGTTTTTCTGTCTCTGGTGT TGGTCTCGTCTGCGCGGAGGCCCCTGGGTCTTTCCTGGTTGGCCTTTGTTAGGTACTTGT CCTTACAGCAGTTCCCCAGTGGTGAGGAACCCCCTGGGATCTCGTGGAAATTCAGTTTTG GGGTCTGCTGGGTGGGCTGGTGTTCCAGAGGGGTGCAGGCTGCTGCTCCCCTTTACTCTG GTGTGGTTTTCCATGGATCGATGTAAAGCTGTGTGTGATGTCCTCCTCCAGTTTAATCTC TGTTTTGCAGTTTTAAATTTATATCAGTGTTTACTTTTACTAATATTTACCTTTTCTTTT GATCCTTGACGTGCTAAAGATTTATTTGTTGCTTTCAAAAGGGCCAATTTTTTTAAATTG ATCAAATATTGAATTTTGTTTTTTTCTTTTTTGAGATGAAGTTTTGCTCTTGTTGCCCAG GCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCCATGTTCAAGCGA TTATCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCACGCCTGGCT AATTTTGAATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGATCTTGAACTC TTGACCTCGGGTGATCCACCCACCTCAGCCTCCCAAAGTTCTAGAATTACAGGCATGAGC CACCATGCCCTGCTGAATTTTCTTTCCTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGTC TCACTTTGTCGCCAGGCTGGAGTGTGGAGTGCAGTGGCACAATCTTGGCTCACTGCAACC TCTGCCTCCTGGGTTCAAGCGATTCTCCTGCTTCAGCCTCCTAAGTAGCTGGGATTACAG GCACACCCCACCACACCCGGCTAATTTTTATATTTTTAGTAGAAATGGGGTTTCACCATG TTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGATCCACCTGCCTCGGCTTCCCAAAGT GTGAGTCACTGCACCCAGCCTTGCTGAATTTTCTTAAAACTTTTTTTTTTCTGACATCTT GAGTTAAAAGTCTTTTGTTATTCTTTGAGACGGGATCTGGCTCTCTCACCCAACCTGGAG TGCAATGGTGCAATCACAGCTCCCTGTACCCTCTGCCTCCTGGGCTCCTGCCCAAGCCTC CAGAGTAGCAGACACTGTTGGCAGATCACACCAGTTAACTTTTTTAATTTTTTGTAGAGA TGGATGGAGTCTTGCTGTGTTGCCTAGGCCGGTCTGAACTCCTGGGCTGAAGCAGTCCAC CTGCCTCAGTCTCCCAAAGTGCCAGGATTCCAGGCGTGAGCCCACGTGCCCGCCAAGTCT TTGTAAGCGCATTTCCGGCTGTGTTTCCTGTGTGCTCCTGGCTGCTCCCTGCGGACTTTG ATGAATAATATTTTCACTGGCATTCATTTCTAAAGAAGCTGTAATTTCATCAGAGTTCCT TTTTAATCGAGAAGTTTGTTCTGAAACATTTGAGTAACGTGGCCTTTTTGGGTTCCATCC ACTCCTCTTTCTAGTCTCCTTCCCGGGCGGTCAGGGAGTGTTGTCTACACGGATCTCTGC CTTGGGGGATTGAGATCTTCTTGCTTGTTCACTTGGGTGCAGATTTTCCAGGGGTCCTGG GGTGATTTTCCTTTGGCTGAGTTTGCTGGTTGGTGTGGTGGGTAAACAAGCGGACCCCGG GGGCCAGTTGCCCACGTCCTGCTCTGCCTTTAGCCAGGGTGTGGCCCTTCACAAGTGACC TACCTCTGCCTCAGTTTCTCTGTCTGTGGCGTGAGGTGGTGGTGAGATTGCCTCGAGGTT TTTATGAAGATTAAATGATTTCCTATTTGTGAGGCACTTTGAGGTGTTAAGTTGAATGAA TGAGAAACAAGCAGGCAGCCTGGGAGATTGTGAACTCCGACATCCAAGTCCGGTCGTTTT TCTTGTGGATTCTTGTTTTCTCCGTGTCTCTGTAACCTCGCGGTGTTGCTTAGGAGCCGT GCTGCTGGCTATGCAGGCTGATGGTTCTTACGTAGTTTTGATGACTTGCACCTTTTGCCA GTGTGGATTCTTTTTTTTTCTTTTTTCCTGTTCAGTGTGTTTTCGCTCTAACCCCCGATT CTCTTGTACTAACATCGCTACAGTTGCTGTTGGTCTCTGCTTCCACCCTCCCTGTCATTT GTTTCAGCTGTGTTACGGAGGCCTTTGCTTTGCTTTTTTGCACACATCTCAGGTTCTCTT TGATAGGAGAGTTTAACCCGTTGTCTTTGTTGTGAGAATACATTTTTTCCCCTCTCCATG AGGGCTTGGATCCGGTTTTGGTGTCTTCTTTCTCTGCTCTAATGGTTTGGGAATTTTGCA TTCTCTTTCTGTTCTTCTTGTGGCTGCCCTTAAACTTGGATTCCGTGTCCGTTTGTGGGA TTATCCGCGTCTATAACTTCGTGATGAGTTCCTGATCTCCGTCTTCCAAAACTTGGGAAG TCATCCGAGGGTTTGTTCCAGATTGTTTTGGGTAATTTTAAAATTTTATTTCACACTAAT TTTATTCTAGGAATCGCTTCTTCATCTTACTGAAGTTTTGATGCGACGTTATAGTTATTT AGGCTTAACGGGAGGTTGCATGGGTTTTGTGGCCGTTTCTGGTGTCTTCCTGGTGTGTTT GGATTTGTGCTTCGCCACGTCCGCACGTCACTTCTGAGCCCAGTGCGGTGGCCCCTGAGC TCCTGCCGGTCACGGGCTGTGTGTTGTCCCCCTCACACCAGAGACAGTCGTTTCTTCTCT TAACTCTTAAGCCCTCCTCAGTCACTCGGATGAACTGATTAAATTCTGTGCTTTTAATAC TAAGCATTAAAAAAAAAAAAACATATGAGGGAAGCACCTGCCACCCAGGCCCATGTTTCT GCTCTCAGCCTTGTGCCCTCCCCCGGTGGCCCCTCCAAAGGGCATGAAGCTGTGGATGCT GTGCCTGTGCCTGGAGGCTCTGGCCCTCCCACCCCTGGCTGGGCTCCAGCTCTAGGTTTG TTCAGCAGCCAACTCAGAGCAGCCGAGGCTCAGGGTGGCATCAGCCGGCCGCGCTGGCTT CACAGCCGACCTCTTCTCCATCATCTGACGGGCGCAGGCCCCCTCGCTGCCACCCCCACT GGTGGGCACTCAGCCTCAAGGCACAGGCCTCCTGGGACTGGTGGCTCCTCTGAATCTTCC TGAGAGAGGCAAGTTTAGTCATCGCTGAGCAACGCAAAAGCGTGTCGGGTTTATTTACTC ACAACGATGTCTTCTAAACCAAAAATACTTGACGGGGCCTTTCTTTCTGTTTTCCGAGGG AGGGGATGGGGATCCTCCTGGAAGATGGTGCCCCCTGCACAGGTGAATGGCGTTTCCCAC ACTTGACCTTGGGAGTTTGGAAACTGGCGAAGCCGCCTCTTCCACTGCCCTTGCTGTTCC CTCCTGAGGTCCCTGGTCGTTCTTTCTCCTCTCAGTTCTGCCTCCCGCAGTCCCTGCATC TGCCACCTTCTCTGTGTGACCCCATTCCTTTCACAGCCAGAAGCCTCTTGGTTAGCCTCA GGTGACTCATTTGCTTCACAGCTGTTTTTTGCTCTCATCTTTTTTTAAGTATAAGCCATC GGTCTGTTTAATTCCAGAACTCTCCTTTCTGGAGCCTGACTTCTTTGGGAGCAGCCGGCG GGTTTCATGGATGCACGGCCACAGCTGTTCCGCTCTTTTCCCCCAGCTGCTGCTTCCAGA GCCTGGCTTTGCGTGGGCATCCTGAGGCCTCCGGGGACCGGGCGGGCAAGGGTGGGGTTT GTGGATAAGGAGTGAGGTGGGGGACGGGCCTGCTGCCCTGAGCTGGGGTCCTGAGTGTCC GCTGGGACTCGGGGGTGGGGGGCCATGCAGTCTTGGGGATACAGGGGCTCTACATGGACT TCGACCCCTGTGTGTGCAGCCTCCTCCGGTTCCAGGCCCCCGGGGTCTTCCCACCAGACT GAGGCTGGGCAGACGGGAGGGGCCTGCGCGTGGCTGTGACCCCGCCAGGGCAACCCCAGA GATTCCCGCCGCCTTCAGGCCCCTGTCAGATCCAAACACTCGGCCTCCGCCCATCTTCGT TTTCAGAGCCTCGGGATTGCCAGTGCCCTCCTGGTGCCCGTCTGTCCAGGGCTCTTCTGA ACACGTCCCTGATGAAACTCTTCTCTCACTTCAGTAGGCTTTGTCCTCTGTCGAACCACA AAGGTTTGTGTTTGAGATTAGCTCCATTACCTGGATAGTGGGAGACAGATCCCGGCCCTC ACTGGAGGCCCCTCTGGGTGCTGATGGCTCACACACCTGAGCTGCCAGGTGGCCCAGGAG AGGGCATGGGCACCTTCTCTCCCAGAGCTGACAAGCCCCGGAGCAAATGGCAAGGAAGTT AGAACAGAACTTTAGAGCTTTTTTATTTTTCTGAGACAGGATCTTACTTTCTTGCCTAGG CTGGAGTATAGTGGTGCAATCTCAGCTCCCTGCAGCCTCGACCTCTTGGGCTCAAGTGCT TCTCCCAACTCAGCCTCCCGAGTAGGGACCACAGGTGTGAGCCACTGTACCTGGCCTAGA ACTTAATGTTTAAGAAGACTCTTGGCCGGGTGCGGTGGCTCACGCCCGTAATCCCAGCAT ATTGGGAGGCCGAGGCAGGCGGATCACAAGGTCAGGAGATCAAGACCATCCTGGCTAGCA CAGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTCGTGGGCACC TGTACTCGGAGGCTGAGGCAGGATAATGGCGTAAACCCGGGAGGCAGAGCTTGCAGTGAG CCGAGATCACGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGAGTCCGGTCTCAAAAAA AAAAAAAAGAAGACTGGACCAGGCACGGTGGCTCACGCCTGTAATCCCAGTACTTTGGGA GGCTGAGGCGGGCAGATTGCCTAAGCTCAGGAGTGCGAGACCAGCCTGGGCAACAAGGTG AAACCCCGTCTCTACTAAAATACAAAAAATTAGCCGGGCATGGTGGTGGGTGCCTGTAAT CCCAGCTACTCGGAGGCTGAGGCATGAGAATCGCTTGAACTTGCAGTGAGCTGAGATCGA GGCACTGCACTCCAGCCTGGGTAACAAGAGCGAGACTCTGACCTTCTACGAACCCTACAT TCAGCTTCCCTTGGAGCGAGCAGCTGCCCAGTGGACTTCAGGGGCGTTCTGGGTCCTGGC AGGAGTCGCCTCCGTCTTTGGTGGTCCTGGCACCCACAGACCCAGTGGGACTGCAGGGCT GGTGTGGTCTCTGCTCATCTTCGCTCGTGCAGAGTTAGGAAACCCTTACCGGGCCTGTTG ACTTGGTGGGTGTGATGTCCCAGCACCAGAAACAGGGGAAATGGCTCCTATACCCTGAGC AGGCTGGGGGTTCTGGTGTGGGGTCCCTGCCGCCCTCCAGAGGCTCCAATGGCTCTTGTG TCTGGAGCTGGAAATGTGGTTTGTTTTCACTCCTCCGAGTTGTGCCTCCCTGGCCCACTG GCTCCTGTCCGCACCCTCGGGCACGCGCTGTGCTCTTGGGACTTCACACCCGAGAGCCGG TCACCTGCTCCTGCTGCACGCCTGCTGGAAGTGGGCTCTGCCTGCAAGGGCCTCGCAGCC GGCGTGGTGAGGGTTGGCTGGTGGGGAGCGGAGAGCCCACCCATCCAGGCCAGAGCCCCT GGAGGTAGAAGGGGCGGAGGGTAGAAAGAGCCTCTCCTGGACTGTAGAGGTGAGGCAGGA GGTAGTGAGCTGGGACCTGGTGCCAGGCTGCCCCACGTGCCGTGGGTGGTGAGTCCGGGG CAGAGTGAACGGGTAAGGCTGGAGGTGAGGTTGGGGACCTTGGGGGCCTGTGGCGAGAAC TTGCTGTTCACCCAGAGGAGGGAGATGAGGCAGTTGGGATGTGAGATCGGGGTGTGCTGT GGGATGCAGCCTGGCGTGGCTTTATCCCCAGAGGGTTGCCACTTAGCGCAGCTGCTCTGC AGTGAGCTGCCTGCACGGCCAGGGTGGCCATGCGGAGACCAGGCAGGCGTCTGAGCCAGA GGCCCAGGCAGGTGGCGGTGCGGGTGCAGCACTGGGTTTGGGGCATATTTAAAAGGGAGG GAGCCTGCAGGATTCGCTGGTGATCCAGATGCAGATGGCAGATCTTGGGCTCTTTTTCAC TTCCAGGTGGACAAGGAGCTCAGTGTTCCCAGGCAGGCCGATGTGTAGCCATAGACAGCG ACAGGTCTTTCTGCAGTGCCCTCTTTACAATCAGAGTTGCATTTCGAGGTGTGTAACGTA CCCGCTTGATGGTGACTGCTGTGTGCACACAGGCCCGCGTGGTGTCGCAGAGCACACGGC GTTGTGTGCGTGGCACGTGTTGTTACGCTGTGACTTTTTTACACTTAATTTCCCATCTAA TACTGGAGACTTTTAGGTGGTGACCAGCCCATCACTCTTCTAAGACATTGCACTTGTCCC CCTGGGCAGGTGTGTTCCACGGTATCTGTGTTATTTCTGATTCCAGTCTCCTGTGTGTGG GGTGTCCAGCGACTCATCGCACGTCTCTGGGCTCCTCTGCGTGTGAGTTGCTTACTTGTT CTTTGCCCATCTCTGTCCTGGGAAGACTGACTTTTCCTTATGTGAGCTGCAGGGCTACCT CCTCCCTCGCCGCCCCACGCTCACTGCAGGGATCGTCTTTCCTTCTGCGGCTGTCGGCTT TCTTCGACCTATCATCATCCACAGTTTTAAAATTTGACATAATTAAATGTATCGGTATTT TCTTCTGAATCTTAAAAATGTTTCCCCATTCTAAGGTCATAAATACATTCTCTTACATTG TCTTGTAAAATATTTTAAAGGTTTGCTTTTTAGTTGGGTTGTAAGCCCCTGCAGTTGACC TTGTGTGTAGAATGGACAAGGTGGAGTTCAACTTTGCCAAGTTTCCACACTCTCAGGTCC CCCTGGGCTCTCTGCTCTGTTCCGCTGGTCTCTTGTCTCCCATTGTGCCAAAACAACAAG GAACTTACTGAATTGCAATGATTTATTTTACCATTAAGTTGTGGTCTTCTGGGAGAGTAC ATACCCCTCCTCATTTTTCTTCTTCAGAATTGTCCTTTTTTTTTTTTTTTTTTTTTTTTT TTTGGAGATGGAGTTTCCCTCTTGCCCAGGCTGGAGTGCAAGGCCTGATCTTGGCTCACC GCAACCTCCACCTCCCGGGTTCAAGCGATTCTTCTGTCTCAGCCTTACAGAGTAGCTGGG ATTATAGGCACATGCCACCATACCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTT TCTCCATGTTGATCAGGCTGGTCTTGAACTCTTAACCTCAGGTGATTCACCCGCCTCAGC CTCCCAAAATGCTGGGATTACAGACGTGAGCCACCGCCGCACTTGGCTTTTTTTTTTTTG AGATGTAGTCTTATACTCTGTCGCCCAGGCTGGAGTGTGGGGGTGCAATCTCGGCTCACT GCAACCTCTACCTCCCTGGTTGAAGTGAGTCTCCCACCTCCGCCTCCTGAGTAGCTGGGA TTACAGGCACGCACCACCATGCCCAGCTAATTTTTGTATTTTTATTACAGACGGGGTTTC ACTATGTTGGCCCGTCTGGCCTCGAACTCCTGACCTCAAATGATCCACCCGCCTCAGCCT CCCAAAGTGCTGGGATTACAGGTGTAAGCCACTGCACCCGGCTCTTTTCTAAACTCTAGA GTTGAACATTCCTTTAGTTTCCAGCTTCATAATTTGGTTCTTATTAAAATAATTCTAGAA TTTTCATGTTTTTTTTAACCAGCTTTCTAAATTGTGTTACATGCACATAAAATATGCCAT TTTAACCATTTTCAGGTGTGTGGTTCAGTGGCCTTGGGTACAGACCCAGTGTTACACAGC CACCACCACCACCATCATCTCCAGAGCCTTTTTATCTTCCCAAACTGAAGCTCTGCCCCC ATTAAACACTCACTCCCCACCCCGCTCCCCCAGCAGGGTTAGATCGCAGAGGGGCCTGCC GGGGGCTCTGAGGTGATGGAAACCATCTGAGACTGCCATGGCGATGATCGAGAAAGTCTG TGAATTTACGGAAAATTATTGCATTATATACATAAAAGAGGTGTGTGTAAACTGTGCCAT AATAAAGCCTAAAAATTAGAAGCATGCTTGTAACTTAGTGTATTTAAATAGGTAATTCGT TCAGTCCTGAGGTTAGTATTATTGAAAAGGTTTAATTTTGTTCTCATCTCTGCCGCTGTC TGTAGTGACCTATAGAGAACCACTGTGATCACCTCCTGTATGTATGCAAATCTGAGCAAA CGTAAACATATTTTCTTCTTGTTTTCCTTCCACAATCCCCCCCACTCCCACCCCCGCCCA TGTGTGTCTGCGTTTTCCCGCAGGTGCATGCAGGCCCGCGTTCATCTGTGCAGCCCTTCC TGCTGCCCTGCGGGCCCCATGCACTGCAGACCCCGCTGCCTCAGACCTGTGCCTGCGTGG CTGGCACACCTGTTCCCTGAGTCGGAGACGGCGGCTGCCTGTTGAGGGCAGGGTGCGTCC GCTGCTTATAGAGACGTGAAGCCCACCATGGCCATTCTGTTGGCGTGCGTTTGTCACCAG CTGTGTTCCCGTATAGAAACGTTTCTCGTCTTTGGGGGGCTTCTTCCTCATTAAGCTCTA TTTCTTAAAGTCCCATGACATACTAATCTAGCTATGCCAGCTTTCTGTTGGTGAATACTT GTGTGATATTTCTGTTCTTAAAATGTCTTAAATGTGACACTGTTTACAACGTAGAGCTAG GTTTTTTAAAAAAATCAAACTTTTTTAGCTGGCACGTTACCTTACACATTCCACGATTTT CCATGGAGGATGTGAGTTGGTTCCTGCTTTATTTTTTTATTTTGCTCTTTTCGTCAGTTT TTTCCTAATGCTTCCTTCCTCCCTGTTGTCTAGTGAATTAGTAACTTTCTTTAATCTCTT TCTTTCTTCCTCTGGTTTGCAAGGTATAAGCTCTACTTCTGTTATACTAGTGGTTACAAA ATGTATAAACTATTTACATTTTTAGAAATCCAAAGTTGGCCCGGCGCGGTGGCTCACGCC TGTAATCCTAGCACTTTGGGAAGCCGAGGTGGGCAGATCACGAGGTCAGGAGATCAAGAC CATTCTGGCCAACTTGGTGAAACCCCGTCTCTACTAAAATACAAAAAAATTAGCCGGGCA TGATGGTGCGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGCGGAATCGCTTGAA CCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACGGCATCCAGCCTGGCTACAG AGGGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAGTCCAAAGTCACTGTAA GTCTGTGCCCCTCCCTGCACAAGCACCCCCACCGCGGCTCTCACCGGGCACCCCCTTTCT CCCTGCTTCTCACTTCTTCCGCCAAACTCCAGGTCTTTCTCCCCGCGCGGCCCCTCTCCC GAGTTCTTCTCGCTCCGGACTCCAGGTCTTTCTCCCCTCGAGGCCCCTCTCCGGAGTTCT TCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTCTTCTCCTT CCGGACTCCGGGTCTTTCTTCCCGTGCGGCCCCTCTCCCGAGCTCTTCTCGCTCCGGACT CTGGGTCTTTCTCCCCACGCGGCCCCTCTCCCGAGTTCTCCCTCCAGACTCCGGGTCTTT CCCCGCACGGCCCCTCCCCCGAGTTCTTCTCCATCCCGACTCCAGTTCTTTCTCCCCGCG CGGCCCCTCTCCCGAGTTCTTCTCCTTCCGGACTCCAGGTCTTTCTCCCCGCGCGGCCCC TCTCCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCTCGCGGCCCCTCTCCCG AGCTCTTCTTGCTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGCTCTT CTTGCTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTCTTCTCCTTC CGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACTC CGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGCTCTTCTCGCTCCGGACTCCGGGTCT TTCTCCCCGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACTCCGGGTCTTTCTCCC CGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGG CCCCTCTCCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCT CCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGT TGTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGCTCTTCTC GCTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGG ACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACTCCGG GTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTC TCCCCGCGCGGCCCCTCTCCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGC GCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCC CTCTCCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCC GAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTCT TCTCCTTCCGGACTCTGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTCTTCTCCTT CCGGACTCCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACT CCGGGTCTTTCTCCCCGCGCGGCCCCTCTCCCGAGTTGTTCTCCTTCCGGACTCCGGGTC TTTCTCCCCGCGCGGCCCCTCTCCCGAGTTCTTCTCCTTCCGGACTCCGGGTCTTTCTCC CCACGGCCTCTCTCCCGAGTTCTCTCTCCAGACTCCCGGATCTTCTTCCCGCTCACATTG TCCCTCTCCTGTGATGCTTGCAGGCGGCCTCGCTCCATCCCACCCCGGAGCAAGGATGTC TCTTGCTTTTTGCACAGAATCCACTTATCTCCCCAGTGGCTCTTGCGGGGCCTTTAATGG GCTGTGCTCAGTGACTGCACCGTGTCGGAGTGGGTATTTCTTGTATTTTGGATTCTTTTG CTTCCTGAATCTGAGGACTGCCCTTCACTGTTGTGGGAGATCCTTAGTCACTGTTTCTTA ACACTTCCTTTCCTTTCTGTTCTTCCCTTTGGGGCTCCCGTCTTCTCCCCTTTCTCTTAG CCTTCCTTTTATTGTTTGAATTGGTGTGTTTATCTCTACTCCTGATGGGTAACTTCCTCA AGTGAATTTTTTTTTAGGACATTAATCTGTCCTCGGCTGAGAAGAATCTGTGGTTCAGCC ATCCACTGAGATGTTAGTTTCCGTGAGTGTTTTTATTTTTAGAAATTGTATCTGATTACC TTCAATACTTGCCCGTCTGTACCCCTGGTGTCCTCCCTTTTGTATCTTTTGTAATTTTAG ACATACATGTTTCAGTTAACCCCCTGTCCATTCTTCCACTGCATTTTTAGGCCCTAACTG TGCCGTTTGTTGCGGCTCCACCTGTAGAAGCGTTTGCCGTGAGCGTCGCCCTTCCTTGTC AGGCACATCTTGGGGGCCAAGCCGGCCGGGCCCTTGGGTGAAGCCTCGTCCTGGGCAGAT TCCTTTTCGCACCGGGCAGGGAGCCCGTGGCTGCTGGGACTCCACAGTCCCCTTAACAGT CACTTTTTATCCTGCGGCCAAACTGCTGGTCACCTGGAAGGCAGCTGTGACCTTCCGCCT GTGGCCCTGCTCAAGGCTTCTCCCTACTGTCTTCCTGCAGTCGCTGCTGTCTCCCCGAGT GCATTCGCAGACACGGGGCCGCCCACTCCCCTTTGCGCCATGTTTGTCCGGACAGGCTTA GCTGGAGACCAAGAACCCAGTGCCTGCGATGGATAAGTAACTGTGGGATTAACTCTCAAC TATTATGTTAATAACACAGAATTAACAGGGTGAGGTTATAGTTCACAAAATGGCAAGCAG ACGATAAACAGGTTTTCAGATAAGGTATGTAAGATTCTTTTTCTGCAGTGTTGAAGTCAA AGCAGATGTCTGATCTCAAAAAGGTCAGCAGTCCTAGATTGAGGAATTAGTGAAATATGT CTAAGGAAGCCTCCAGAACCGTCCGGGGGAACCCTCCTGCTGCGCTCTCACCAGCGTCCT TTCCCGCAGGTGAGCATCTGCCTGGAGTGTAACAGCAGCAAACTGCGCGGGCTGAAGCGG AAGTGGATCCGCTGCTCAGCCCAGGCGACCGTCTTGCATCTGAAGAAGTTCATCGCCAAA AAACTCAACCTTTCATCCTTTAACGAGGTAACAGTTGATCCCTAAGTAGAAACCATAACA AGTCCTCTCTTATTTCTAAAGGTAACTCCAAGATTCTTTGCTTAGTTTTGTTTTGTTTTT AACAATTTTGGAGATTTTAACCAGAAAAAAATCCGTTTTGCCTGCTTCACCGGGGAGCGG GATAGGAGACAGCCCTAAGGGTTGTAGGATGCCCAGAGACAGGGAACGTGGAATGCTACT GTGAGTGGAAGAGAGAACTAGGGCGGGGATGATGAGACTGTTTTAAAATAGGATAAAGGT TTTCCTCAAAACGAGAAATTCTGTGCTTTAATTTCACAAGGGGAGACATGGGCGGATGCA GAGAGGGAGGACCCTTCCAGGCTGTGGTGTGTAAGGAGACGAAGGAGTGCTGGCATGAGG CGGCCTTGGCAGCGGGCGCACCATGAACATGCCAGTGTGGGTCCCTGTGAGCCCCCAAGG CAGTGACACCATGGGGATGCAGGCGCCAGCAGGGTCCAGCTTTGCATGGAGACAGAAGGC GCTGGCGGCTGTGGGCAGGAGCATGGGTCTGGTGTCGTTTTTGAAAATCGCTCAGGCTGT GCAGAAATGGACGCAGGAGAGGCCAGCGCCAGGAGTTGCAGGAGAGGCGGACTGTGGTGG GGGCGGTCAGGGTGGAGAAGTGGACAGACTTGAGATGCTGTCTGTAGCAGCAGTGGACTC AGTGGTGGCCCCAGAAGATAAGCCACATCCTAACCCCCAGAGCCTGCAAATGGGATCTTG TTTGGAAAAGGATCTTTGTAGATATAATTAAATAAAGGATTTTGGGATGAAATAATTCTG GAATATCTGGGTGGAGCCTAAATCCCATGACACAAGTGAGGCGGAGGAAGACTCGAGACA GGAGGCCCTGGTGAGGACAGAGCAGAGGACGGACTGGAGGCTGGAGGGAGGCAGCCTCGA GGCAAGCCAGGGAGCCCCTGGGCCACCAGCAGCTGGAAGCCAGGGCAGGCTCCCCGGCTG TGGTCCGAAAGCATCCCCCAGATTCATGTTGGAAATTCCATCCCCAGCAGGGCAGTGCTG GGAGTTAGGGCCTGGGGGAGGCGCTCAGGCCGAGGGCCCTGCCCCATGCACGGATTGATG CTGCTGTGAAAGGACTGGCCAGCATGTGTTCTCACTTCTGATCTTCCCCAACATGAGGAT GCAGCAGAAGGCCTTCACAGGTGGCAACGTGGTGACCTTGAATGTCCCAGCTCCCAGAAC TGTGCCGAAATCAATTTGTTCTTCATAAATCACCCAGTGTGTGGTGTTCTGTGGCAGCAG CACGGAATGGACTGTGCTTCTCCCCTGGAGCCTGCAGAGGGAGTGTGGCTGTTATGGACT CTGGAACTGAGTACATTTCTATTGTTTGAAGACACCACCTCGTGATAATTTCCACGGCAG CCGCAGGAGACTAATTCAGAGAAAGCCACAATAAGTTGCTGATGTATTTGGGTGGTGATG CAGAGAAAAGGAAGGGGTCAGGAATGACTGCAGGCCTGGGGCTGCTCGGTTTGGGGTGGG GGGTGGTGTCTCGGGACAGGCTGGCGTAGCTGCTGTGGTGGCACAGAGCAGAGGCTGTCA GGTCATGGGGGGCCAATGCCAGCCTTGAGTGTCCCACAGGTTGGCCGGGGATACGGACAG CACACCGGGGTTGGGGAGACTCACTGAGCACGGGCTGCCTGGAGATCATGGAGAAACCAA GTCAGGACACGGGGGGAAGGGAGAGAAGGAAATGGGGCAACGCTTTTTGCTAAGTTTCTA TCGTTTTGTTTGCTTTTCTGTGTAGCGAAACAGAAAAGATGGATGGTAGCTGGGGACAGA GCAGGCCGAGGAAGTCCTTGGATTTTCATGTGGAGGTGTAGCGGGAAGCTGCCGGACAGT GGGGCTGCAGGGGGTGGGGAAGAGGTTGGCCATTTCCCAGCGCAGGGCTGGTTCCTCCAG GGAAGAGTGTGAGGTTTGCGCTGCTGCTGCGTTAACCGTGCCTCTGAGCCCCCAACCCAG CCACTCAGGCAGGTGGGGCTGCTTCAATTCATGCCTTCCCCAGGGAGGAATCTGAAGAAC TGTCTACATGATCAGGGAAACGCAAGGAAAACTGCGTGGCACCACGCGTACCCCATAGAA GGGCCAGAATCCCAAGCACTGACAACACATTCGGGAAACGCCGGGAGCGCAGGTTCATTC CTGTGGGAAGTGGAACCCGCAGGCCCTGTGGAGAACAGCTTGGCAGCTGCTGACAACACG AAACACACTCTCGGCAAACCACCCAGCAGCCACACCTCGTCATTTACCCACTGGAAATCT CCTGCCCACACAAAAACCTGCACCCGGATGTTGATAGCATCTTTCTTCATAATTACCAAA ACCTGGAAGCGACCAAGATGCCCTTCAGTAGATAAGTGGAAAAATAAACCGTGGTGCATC CATACTGGACTATTATCCAGTACTGAAAAGAAATGAGCAGTCGGGCCAAGAGCAGGCACA TGGGAGAAACATCAAGTCCCTGTTACTAAGTAGAGAAGCCCCTCTGAAAAGGCTGTAGGC CGTGCGACTCCAGCTCTGCAGCATGGCGCACTGGAAAAGGCAGAACCATCCGGAGGCTGC AGGGGCTTGAGGAGGGTAGTAGGAGTGGGCGGGCACAGGGCTCCTGGGCGGCGATGCTGC TGTTTGTCCACCTGTGGCTGTGCCACCAGGGCGACCTGACATCCGCTCTGGACTCGGTGG AGGTGATGTCAGTGCAGGTTCCTGGGTGGTGACTAATGTGCCCCCATGCAGGGTGTTGGT GGCAGGGGGGTTCCAAGGGGGACGGGAACTCCCTGTACCTTCCTCTCAATTTTGCTGTAA ACCTTAAATTGTTCTTTAAAAAGTCTAATTTTTTTAAAAGACTGGGGAGCCTAGTGCATT TTTGCACTATGGTGAGAGGGAGGGACAGCCTGGACCGGAGGTAGGGCCTGTGGGGAGAGG GTGCCCCTGGAGGCTGCAGCCGTGGGAGGGGGCTGGTGTGGACTGGGCCTGGGTGGGATG GGGAGGGAAACACTTCGGCCCTATGGGCCTCTCAGGCACCTGTGCCACCTGGGGAACCAG GGTGCCCGATTCCGGAGCTGTCAGGGCTGCTCATGGGGCTGCAAACCACCTCTTCCCGTT GCTCAGTACGGCAGGTGTGGTAGACAGGGTGTGATGGGGCCTGTCAAGAGAAAAAGGGTT CAGGGCAGCTGCAGGCCAGATAGGGGCGGGATGGGAGCCCACCACTGCAAGGAGCTTGTG CCTGCGCCTGCACCCCCTGCAGAAACGTCATCCCCCTAACTGGCACGGGCCTGCCCTGTA ATATCTTATATGTTGCACTGGATTTCCGTTCAGCTGTGAGGTAGGGACCACACTCCATCT CTAGGCTGTGAGGTAGGGATGGAGGAATACATGAACCAGCCCCCCCCACCCCATCTCTAG GCACGTTCTTGCATGATTGGGGAGGGGCTGCAGATTTCATACCAGCATCAAGGTGGCCAT GTCAGTGTGGGTTGAGCACCTCTCCGCTGCTAATCAAACCTCCTTATCCCCCAGCTGGAC ATTTTATGCAACGAGGAGATCCTGGGCAAGGACCACACACTCAAGTTCGTGGTTGTCACT AGGTGGAGATTCAAGGTGAGACACGTGATTTGATTTTCAGAGTCTGCTCTGAATGGCAGT GACTTTGCTGTGCATCTCTTATCTAAAATGTTAAATGACTCCAGCTGGGTGCAGTGGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGACGAGGCGGGCGGATCACGAGGTCAGGAGATC CAGACAATCCTGGCTAACATGGTGAAACCCAATCTCTACTAAAAATACAAAAAATTAGCC AGGCGTAGTGGTGGGCACCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGT GTGAACCCGGGAGACGAAGCTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAACCTAG GCGACAGAGGGAGACTCTGTCTCAAAAAAAAAAAAAAAGTGATGACTCAGCTACAGAAAT TGTTGTGAAACACAGTTCTGGTCTTTCTGAAATCATCAACCCCAGAGCCAGCTTGGAAGG TGCCAGCTGAGCTGCGAAGGGCACAGGCCCTGGTGGGAAAGTGCTGAGGCCATGAGTGCC ATGAGCAGAGGGTCCCCTGGGGCCTTTGGGCCCCTCTGAAGCAGGAAACCAATGGTGGAA CTCTCCCACCTCAGCTGGTGTTGCTGCCTGGGGAGAGGGGGAGGAGCCAAGGCTGGCCTG GGGCTGGGCCAGAGGGTTTGAGGGAGAAGGGGGCAGGGGAGTGGCAGCCAGGGCCACATC AGGTACAGGTGGCCACCACGGTGTGCACAGTGGTCACTGGGTCACCTGGGGCCAGGGGAG AGGGCACATGTCTTCCTAGCCCGTCTTCCCCCAGCAACTTCTGGGGGACCCTTCTGTTGC TCAGAACAGAAGGGTCTCTGTGCAGCCCTGCATGTGGACTGTGCCTCACGGGACGTGATT CCTCAGCACCCTTCCCGATGAAGTAGGTCCTTCTCGCCTCCACCCCTGCTAAGCAGGCAC TGTGCGTTCTTGTGTCTTCCAGAAGGCGCCGCTCCTGCTGCACTACAGACCCAAGATGGA CTTGCTGTGAATGGTGCCACACAGCGCCCACAGACTGGGCCCTCGCACCCTTGGGTGCTC CCGGCCGCCGCGCTTAAGAACATTGCCTCTGGGTGTCATGTGGACCAGACTTCTGAATAG AGAATATTTATAACTTTTGTATGAGAGAGAATTCACACTCAACAAGACACTACCAGCACC ACGTTTACAGAGGATGAAAACACTTCACAGTCTCCCAGAGCCGATCGTCCTCTCCCCCGC CCCACCCCGTGCTTCAGCCTTGCAGGGAGAGTGATGCTCCAGGCAACACGGTTCTGAGTC ACCTTCTGACACGAGCTCCCTCTGCTTGCTTTCCAGGTCTTGAAAATCTGAATTCACTTC AGTTTAGTTTATGAATTTTAGGTTTCATGATAAGCCTCAAGTGTAGTTGGACTTTTATTG AATCCTTCCTAAGTTATTGAAAAAATGTCTTTTCATGGTGAATGACAATATTTATGTTGC CTTTAGCTTCTTGAAGATTTAGAAGTTATATAAAAAATTAATTTAAAAGCAAACCAAAAG AGGTTTCCATTAACATTATGATTTAACCATTGTATTTAATTTCCCACCTTATGAAACACA ACAGCAGCTCCCTGACTGGTTCGCCTTTCATTGTGTGAGGTCGGCACTTGGACTCACTCA GAACTGTCGCTCACCTGTGGCTGACACACCCAGCCCTGGAAACGGGGCCCCAGACGCCAC GTCGGGATTTCTGACATGCTCAGCAGGTAGACCAGAGGCCGTGTGACCAGCTCAGTGCTG GTTTACGGAACAACTCTTACTTTTAAAAATTACTTGTTCCCCCAAATTGTTGAGTGCCGC CGTTTGGTTTCCTATGTTTTCTTTCCCTGTTTTGATTTTGCTGAAGGGAGAGGTGGTGGT GGTTAGGATCAGAGCTCTCCTGGCATCCGTGGGGAGGATTTGCTGGTGGTGGCTTCGGGC TCATGCCCAGACACACTCACTGCCCCGTCTGTCCAAGGCCTCCCCTTCCCCTTTGCTGGT GGGAGGAGCTCGTGTGCTCCTTGGCCGCTTACTGGAAGGGCGTTTTTCAGAGCTGCAGGG ACAGGGTGAGCAGCTGAAGGGCTAGGAGGGAAGCCGGCCCCCGCTCTGCAGAAGCTGCAT TTCAGCTGAATCTGTGTTTCAGCCTCAGTTGGTTGCACCGTTAGCCCCTCTCCTCCCGGA TGGTCATGTTTTTGTCACATTAGAGAATAAACAGCCACACACACATTTTTTTTTTTCCTT TAAAACAGTAACTTGGAAATATGAAAAGGCCAGAAGGAGGAGCAAGGGCTGTTTTCTGGA GTGGTTGAGGTGTTGTCCTGCAGTTGTCATTGTCTTCTCCACCGGGCTGTTCCCATTTAT TTCCTGTGGAACTGAATCCCTCCTCCCTCCACTCCTTGGGAGCCCAGGTGGTCCTTGGCC ACCATTCAGGCTTTCCAAGAAGCCAACCACCTTGGAGATTTTTTTTCTTGAATTTCGCTG TTTTCTTCTGCTTCCTTTAGATAAAAAGCAGCTCAAGAGACCTTATCTTAGGGATGAGAA AAACATGCATATTAATTCCATCTGAGTGATTGTCAGTGTAAGGCCTTTTAAAACAAAAGC AAGTTCTTTGTTAGGAATTGGTCAAAATTCATCTCTTTCTTTAAGCCCATCAACTCCCAG GACGGTTTGAGTTACTCAGTTACCTAAGCTTGCTATTCATCCAAATCATTTTCTAGAGTC ACTGTATAAGGGTCTATGAGTAGCTGTGTATGAATAAATATTACCTGTCTACCTCAAAAT ACACATACTGCTGAAGCATTCTGTACAACCGTGTGTTATCACAGTGCAGTTTTAAGTGTA ACGTTAGAACTTAGGCATTTTCCTGTGTGGCGGAATAAGAAAGGATTAAACAGTTACAAG CCTCCAAATTCAAATAAAATTAAATCACAGTTCAGATGAAACTGAATATCATTGTAATAA TCTCATAATATATATTTGTAACTTTGTAGCTATCTTTGAAATCACTTGACTTTGCAATGG TGCTAAGCTGATAGATTTAAATACACAGACGGGCGAGTGGCGCCCGTGTCGATGTCTTCA GCCAGTGGTGACCCTGCTTTTGTAACCGCGTTAACCTGACAAAACCTCAGCAGCAGAAGT CCCTATTTTTCTAGGAGTTCATCGTGCAGACAGTCTTCACTACAGGACTCGGCCCTGGGG CCTCTGCCTCTCGTCTGACCTTGCAGCCTTAGTCGTTGGAGGCTGGAGCGCAATGGCCCT GCCGTCTGTGGAGCCTCTGGGCGGCCTTCTTTCCTTTCTGTCAACCTCTCATTTCACAGA AAAAGGCTGAATTTCATTTTTTCCAGCATGAAAGCCAGGATCGGTTAGTGGTTGGATTCT ATTGGTTTTTTTTTTTTAAACAGATGGAGTTACTGTGAAGAAGTTTTCACAACTATTTAT GCTGGTAAAACAAATGCTGTTAAATCACCTTATGCGTCGTTTTCAACAGCAGTGGGGCTA ATTACCCGGAATACGGTCTCACCGATGCAGTTTTCATGGACATAGAAAATTCAAATAGAA TATATAATATTGAATTTAAGATTTGGGGGGTTAAAAAAGAAAACTTAACTTTATAAAATT ATTTATTCTATTTTAAGCCTTCTATCATATTTTCCCATCCAATTGTTTGGTTTCAGTGGT CCAGCTTTATTTACAGGCATATAAAATGAAATTGTGAGATGTTTTGCAAGCTTCTTTTTA CTTTGAGTAGCTTTTAATTTGTATGTTTTTATGTGGATGAAGAGCATTTTTTATGCTTTT GTGCAATAGGTTCCAATATGCATTTATTAGACATCTGTTTAAATGGTAATGTAGCATTTA TTTTGCTAAATTGAAAGGGAACATAGATGGAATTCCAAAATATGTACATTCAGCTGTTTG GTTTTTCGTTTTTCATTGTTATTATTGTGAGAATGCTGTTATTGGGGTTGTGTGTGAGTG CCCGTCAGCCAGTGATGCCTCGGGCCACGCTGTGGGGCCACCTCAGTCCTGCCTGGGTCC TGGTGCCTTGGACCCCACGTGCTTGTGGCCAGGCTGCCCCTGGGCAGGGCCATGTGGCCT CAGACCACAAGAGCGGAGCTGCCCTGGCCCAAGCACTGCAGCTGCCTGCACCCCCGGGCT TCGCAGCCTTGCTTGTTTTCTCTGAACAGCAACAGAACAGTGTTCACAGCGATTCAAAGG GTGGCATTGGGTTGGACGTTCTGGGTACAAGCCAACCTAGTCCCACGTTGTACGTGAATG TTTAATGTGCTCTCAAAACATGGAAAATAAGTTTAGTGCACATAGCTAAATCACAAAACA TCCAATTTCTCTGTTTCCTCAGGAAGTCATTACTGCGCCACCACATCACATGACCTTAAC ATGATCAATGTATTTCTCTGCCTTGACATTTAAATACATAAATTGAGATAAGTAGATTAG AAAATCATTCAAATGATACCATAATTTGTACGGGACAGGGTGCGGGCAATGGCCACGTGG CCAAGGCCCTGCAGGAACGCGCCGAGGTCTCCCTCACCCTCCAGGTGTCCTTCGCACCCA ACAGTGCGTCTGAGGAACGAGCTGCAGTTTGAGCGTTCCCCTGAGATGTGCGTAGCCTCC GTGTAAATGTCCACTCCCATGGCTTAATTGCCTATCAGACGCATTTTCCCAGACGAAAGC AATGTTGGGTTGGGGAAGACAGTGCAGCCACCCAGCCTTTACCAGCAGCGTACGGCAGAC GAAGGCAGTCGAGGTGTGGAGGTGATCACGAAGATACATGTGTTTGACTGTTTAATTTGA AAGTTTACATTTTTTATGCTTTGTGTTGGTGTGTAATTTTTGTACTCTTGGTGGCTAGTT TTTGTCAAATCTTTTTTGGAATATTGCTTAAATGTTTTGATTTTATGATAGTGAAGCTTG TATTCAGTGTTTTGCCAATTAATATTATATGCTTGTAATAAAAGCAAAAGAAAAGCTTAA GTGAAAGTGTTTCTGGCTGGAAATGTATTACATAAATCATTTGTATGAGCATGAGAGATG ACTTGCTCATGGGATGAGCAATGCTGTGGGTATTGGATGGACCACTCAGGCAGCCTGGCC GCACACACACACATGCATGCTACATATGTGTACGCTCAGACCACATGCCTGCACATATGT CCACACACCAGCCCACGGCTCCCTTCCTCACCCCAGCCCTCCCCACTCCCAGGTTAACCA ATGTCTCGATTTGCTTCAGGCGGCATTTGTAAACTGTCACCCTGCTTGCAAACCCTCATT TAAATTGGTCCAGCATTTGCTACCAGAGTTTAGGCCACAAACTTTGTAAAGCTCAGTTTG TCTCCTTGCAGAAAGAGGTTGCTGCAGTTTGGAGCTGGTTATGCCAAGGAAAATACGGCT AAAAAAGAACTTACTGATTCCCATAGGTGTGTCAACTGACAAATGAATGTTCCATCTCCC TACGACAATTTGCTGCCCCTCCCCAAAAAAAGCACTATGGCCAAAATTTCAGTTTTTAAA GGTTAAGTAAAATACAACAATTCTGAAACTCTTAAGAGAACCAGAATTGGAAGGAAAGGA GAATGGCCAAAATTATATTCTCACAACCTAAAGCAGTAAACTTTAAAAATAGGTTCAGTC TTAGACTTGACTTAATTGACTTAGGCTGGGCATAGTGGCTCACACCTGTAATTCCAGCAC CGTAGGAGGCCAAGGCAGGCTGATCATCTGAAGTCGGGAGTTCGAGACCAGCCTGGCTAA CATGGTGAAATCCCGTCTCTACTAAAAAATATAAAAATTAGCCGGGTGTGGTGGCAGGGG CCTGTAGTCCCAGCTACTCAGGAGGCTGAAGCAGGCGAATCGCTGGAACACAAGAGGCAG AGGTTGCAGTGAGCCGAGATCACGCCACTGTACTCCAGCCTGTGCTACAGAGCAAGACTC CATCTCAATTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGACTTGGCGGGGTGCAGTGG TTCATGCCTGTAATCCCAGCACTTTGGAAGCTGAGGCGGGTGGATCACAAGGTCAAGAGA TCGAGACCATCCTGGCCAGCATGGTGAAACCCCATGTCTACTAAAAATACGAAAATTAGC CAGGCCTGATGGCACGCACCTGTAGTCCCAGCTACTCAGGAGACTGAGGCAGGAGAATCA CTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCACCACTGCACTCCAGCCTG GGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAGACTTCACTGA CTCAAAGTGTATTTTACTTATTTTCGGCCAGTCCATCTGTCCATCTTAGAAATGTCAAGA TACTGGCTGAAACCACAAGCAGACACTGATGTCAGCGTCAACTGCAGGGAGTAGGGGAAA CACAAGTCCTCAAAATTGGGTCCACCCACTTTGGGGACTGGGCCATGAAGCCTGGTGATA GCAGCCACGGGAGCCTGAGGTCTGAGAGCTTCAAGCTCCATCTGAGCACAGTGGGTGGGG TCCCTGCACCAGGACCCCAGAAACAAGCTCTGGAAGTTGGTTCCTGTGGGTTCTGCAGCA GCTCAGGGCTGCAGGGACCTTGACGCTCTCACAGCAGAGCCAAGCCTCGGCCTCTCTGCT CGCTGGTGGTTTTGTTTCTCCCATGCAGTTCTGTGTGCATAAGACAAAAATCCTGTGTTA GTCATGTGTGTTAGTACACCTGTGACCGGGTGAAAGCCAAACAGTGTCCCCTGAAAGGCA GCAGAGGAACAGAAAAACAAGGGGGTTTGCTGTGATGAGACCCGCACCGTCTGCGTTCAG GAAGCCAGGGCCTTCTGCTGCTAGAGGCCCCTGAGGCCCACCAAATCCTCCCAAAGTAGA TGTCCATATGGCTTCTAGTTTTTAAGGATAAAACTCCCTTGAGATGCACTGAGTCCCTCC TGAGGGGCTGTGGAGGGCTGAGCCTGCATTGGTTGGGAGGCCTGTGTCCTGACGGTGCTC TGCAGTAGCTACACTGAACGTCCCCTTTAATAGAAAGAATTATCTGTCTTCCGCTTACAC AGAAATGCAACTGTGCTTACATAAATCAGCACAGAGTCCTAAATCCATAAATAAGCAAAG AGTCCTTTCTCTTACCCACATTACTCCTCAGTCAAGGAAAGTACACAAAGCACATTTGTT TCATTTTTTTTGGTGGCTTATGCTCCAATTGTGAGGAAGGAGATGCTCCCCTGGGCCCAC CCCGCCCACCCCAGAGTGTCTGCCCACGCCAATTCCTGGGGAAGGTGTGGCCTGCTCAAG GGATAAGACTCCTGTCGACGTTGGACAAACAACCATTTGACCACTACATTTATTCCTATG TTTTTTCTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGACAGAGTCTCACTGTG TCACCCAGACTGGAGGGCAGTGGTGTGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGT TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAACTGGATTACAGGCACCTGCCACCACG CCAGGCTAATTTTTGTTTTTAGTAGAGACGGGGTTTCACCACGTTGGCTGGGCTGGTTTC TAACTCCCAACCTCTGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGC GTGAGCCAGCGCGTCCAGCCGAAGGTTGCTTTTTTAAAGCATTTTTAGTCAAAGTCTTTT GAAAGATGAAAGGTCTGGCCTTGGTCACAGTAGTCCTGCTGTGAAGACGCATGAAGGTGC CCTGGGTCAGGGGAGCAGCCAATTTCACTGACACCCTGGGACGCACAACCAGGACCTGAC CTCTTGCTGGGAGATTACCCCGAGACTTCAGTCATCACCATGCACACTGCCTTGTAGGAA GGCTGGGAACCCTCAGGTGGCGACAGCCCCCAGTCTGCCAGGGCCCCTCAGAGGTTGAGG GGGCAGGGTCCCTCCTCACATTTCTCACCTGCAGCTGGTGCCACAACTGTGAATGTTGGA GTTGTCCAGTCCCACAGCTTCCTCTGCCCCACAGCACAGGGCAGATTGGCCTGCAGGGCC TCATCACCCCCATTCTCTGAGAGGAGATGTGGCTATCTCTGGCAGGCCTCGCTCTGGCTG GTAGCTTTCTCCTGGGCTGCCATCTTCTAGTGCCAGTGAGGACTCTGGTCATCTCACCTG CTTAATTCCCATACTGTGTTGTCCACAGCTCTGCTCGGGTCTGGTAGTGAGAGGTGACAG TGTGCTGGCAGCCCTCTCAGCCCTCGCTTGCTCTCGGCACCTCCTTGGCCTTGGCACCCA CTCTGGCTGCCCTTGAGGAGCCCTTCAGCCCGCCGCTGCACTGTGGGAGCCCCTTTCTGG GCTGGCCAAGGCCAGAGCCGGCTCCCTCAGCTTGCAGGGAGGTGTGGATGGAGAGACAGA CGCGGGTGGGAACCAGGGATGTGGGCAGGCTTGCAGGCCAGCAAGAGTTCCGGGTGGGCG TGGGCTCGGCAGGCCCTGCACTCAGAGCGGCCAGCCGACCGGCTCTGCTGGCCCCGGGCA GTGAGGGGCTTAGCACCTGGGCCAGCAGCTGCTGTGCTCAATTTCTCGCTGGGCCTTAGC TGCCTCCCTGCAGGGCAGGGCAGGGCTCGGGACCTGCAGCCCACCACGCCTGAGCCTCCC ACCCCTTCCATGGGCTCCTATGTGGCCCCAGCCTCCCCGACGAGCACTGCCCCGTGCTCC ACGGCACCCAGTCCCATCGACCACCCAAGGGCTGAGGAGTGCAGGCGCACAGCACAAGAC TGGCAGGCAGCTCCACCTGCAGCCCCAGCGCAGGATCCACTGGGTGAAGCCAGCTGGGCT CCTGAGTCTGGTGGGGACTTGGGAGAAGCTTTATGTCTAGCTAAGGGATTGTAAATACAC CAATCGGCACTCTGTATCTAGCTCAAGGTTTGTAAACACACCAATCAGCACGCTGTGTCT AGCTCAGGGTTTGTGAATGCACCAATCGACACTCTGTATCTAGCTACCCTGGTGGGGACG TAGAGATCTTTTGTGTCTAGCTCAGGAATTGTAAAAGCACCAATCAGCACCCTGTCAAAA ACGGACCAATCAGCTCTCTGTAAAATGGACCAATCAGCTCTCTGTAAAATGGACCAATCA GCAGGATGTGGGTGGGGCCAGATAAGAGAATAAAAGCAGGCTGCCCGAGCCAGCAGTGGC AACCTGGTCCTGTCCCCTTCCACACTGTGGAAGCTTTGTTCTTTTGCTCTTTGCAATAAA TCTTGCTGCTGCTCACTCTTTGGGTCCACACTGCCTTTATGAGCTGTAACACCGCAAAGG TCTGCAGCTTCACTCCTGAAGCCATCGAGACCACGAACCCAGTGGGAAGAATGAACAACT CCAGACGCGCCGCCTTAAAAGCTGTAACACTCATCGTGAAGGTCTGCAGCTTCACTCCTG AGCCATCGAGACCACAGACGCAGTGGGAAGAATGAATAACTCCAGACGCGAAACCTTAAG AGCTGTTAAGACTCACCACGAAGGTCTGCAGCTTCACTCCTGAGCCATCGAGACCACGGA CCCAGTGGGAAGAATGAACAACTCCAGACGCGCCACCTTAAGAGCCGTAACACTCACCAC GAAGGTCTGCAGCTTCACTCCTGAGCCATCGAGACCATGAACCCAGTGGGAAGAATGAAC AACTCCAGACACAGCACCTTAAGAGCCGTAACACTCACCGCGAAAGTCCACAGCTTCACT CCTGAGCCATCGAGACCACGAACCCAGTGGGAAGAATGAACAACTCCAGACGCACCACCT TAAGAGCCGTAACACTCACCACGAAGGTCTGCAGCTTCACTCCTGAGCCAGCGAGACCAC AGACCCACCAGAAGGAAGAAACTCCAAACACATCCGAACATCAGAAGGAACAAACTCCAG ACACGCCACCTTTAAGAGCTGTAACACTCACTACGAGGGCCCTCGGCTTCATTCTTGAAG TCAGTGAGACCAAGAACCCACCAATTCCGGACACAGTAGGACCCCCTTTATGGTGTGGGG TTTTTTTTCTTTTTTTGGAGACAGGGCCTCACTCTGTCACCCAGGCCAGAGTGCAGTGGT GCAATCATGGCTCACTGTAACCTCGGGCTCCTGGCCTCAAGCCATACTCCCACCTCACCC TCCAGAGTAGCTGGGACTACAGGCACCACCACACCCAGCTAATTTTTTATTTTTGTAGAG ATGGGGTTTTGCCATGTTGCCCAGGCTCGTCTCGAACTGAACTCAAGCAATCTGCCCACC TCGGTTTCCCAAAGTGCTGGGATTATGGCAGGAGCCTCCACGCCAGCCCTTTTTCTTTAT TTTGTGTGTGTCTGTGTGTGTGTGAAAGAGAGAGTACCATTCTGTCACCCAGGCTGGAAT GCAGTGGAGCAATCTCAGCTCACCACCAACCTCCACCTCCCAGGCCTAAGCAATTCTCCT GTCTCAGCTTCCCAAGTAGCTGGGATTACAGGCACCCACCACCACACCCACCTAATTTTT GTATTTTTAGTAGAGATGGGTTTCACCATGCTGGCCAGGCTGACCACAAATGACATTCCT CAACACAAATGATCCGCCTGCTTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCA CCTCACCCAGCCTTTTTTTTAATGTTGGCTTTTCTTCTGTTAGATCAGCTCCAGAAGCAG CTTATCCTGTGTCATTTAATCTCATCAGAATTTAACTAGGATTGCAATGAATGTACAGTT TACTTTGTGGGGCAGCTGACATCCTTCACCCACGATGTGGCATGTCTGCCAACTCACCCT CTTTTAGCATCTTCCTCAGGCGGTCCTTACACACTTCTCTTCCAGCTTTTGTGATTCTTT CATATGGAGGTGGAGGGTTGTGGCTCATGCTCCGATGGGTTATTGTGGAGTAGAGAAACC CACTGGATCTGGCACGGACTGAACTCCTCGGCTGGTCCTCAGGGTTCCTCAGGGGATTTT CTTGGATTTACATGCAGATGATTGTATCATCAACAAACTACTAAACCCTGTCTCCAATAT TCATCTCCTTCCCTCTTTTTCAGTTCTCTCACCCTGCTGGGATGTCTGGAAAACACTCAC AGTGATAGCAAGGAGAACTGTGCTTGTCTGACTTTAATGGGAATACTTTAAATATCTTGA CTTAAGCATGATTGCTGCAGGGTTTTGACAAATACCATTTACCAAATAGAGAAATTATCT TCTGTTACAGCTTATTAAAAATCAGGAATGCCGGGGGCAGTGGCTCACACCTGTAATCCC AACACTTTGGGAGGCTGAGGCAGGTGGATTACCTGAGGTCAGGAGTTCGAGACCAGCTTG ACCAACATGGAGAAACCCCGTCTCTATTAAAAAAAATAGAAAATTAGCCAGGCATGGTGG CACATGCCTGTAATCCCAGCTACTCAGGAGGCAGGAGAATTGCTTGAACCCGGGAGGCAG AGGTTGTGGTGAGCCGAGATGGCGCCACTGCACTCTAGCCTGGACAAGAAGAGCAAAACT CCATCTCAAAAAAAAAAAAATTCAGGAATACGTGTCCATTTTTAAAAATGTTTTAATATT TTAAACTAAAATTTTTAACTTTTTTGTTTGAAGCTTTAACACATGTACAGTCACGCGACC ACCACCACAGTCCACACACAGAATGGCTCCACCCCCAAATCTCCTTAGTGCCACACCTGA CCACGGCGCCTTCCCCCAACCTTCCTTCACCTCTTCCCACCCCCATGGTGCCCAATGTGT CAGTCTCTCCCCATTGTCACTGCAGAGGAGTATTTCACTGCATAGATATACCACAGTTTA CCAGTTCACCCAATGAAAGGCATTTGAATTTCAGCTTTTGATGATTATGAATAAGGCATC AGTAAACATTTACGTACAGTTTTTATGTGGACTTAAGTTTTTCATTCTCTAAATACCCAA CAGTGGGATTGCTGGGTCATGTGGCTGTGTACATTGAACTTTATAGGAAACCACCATGCC GTCTTCCATTTCCAGCAGGTCCACACCCTGGCAGCTTGGGGCACCACCAGCATTCTCTTG CACTGCGGCTGTGGTGCAGGTGCCTCGTGTCCTGCGTGGTGGCTGAATCTGCATTTCCTG GTGGCTGGTGGTGTCAAGCCTCTTCTCCTGTGCCCAACAGTCAATGCTGTGTCATTGCTG GTGCATGTCTGATCAGGTCTTTTCCACTTTTTAGTTGGACTGTTTTCTTACTGTTGAGTT TTAAGAGTTCTCTGTGTATTCCAAATACAGGTCCTTAGTTGACAGGTGATTTGTGAATAT TTTCTCCTCATCTTTTCATTCTTTTCACACTGTCTTTGGTAGTTCAAACGTTTTTAGGTC AGGCACGGTGGCTCATGCCTGTAATCTCAACTACTTTGGGGCCGAAGGTGGAAGGATCAC TTAAGGCTAGGAATTTGAGACCAGCCTGGGCAATACAGCAAGACTCAGACTCTGGAAAAA ATTTTTAAAACCAGGAATAGTGGCTTGCACCTCTAGTCCCAGCTACTCAGGAGGCTGAGG AAGGAAGATGGCTTGAGCCCGGGAGGTCGAGGCTGCAGTGAACTATGACTTACCACCACA CTCCAGCCTGGACAACACAGCATGACCCTATCTCAAAAAAGTAAGTTTTTAATTTTGATA AAGTCCAATTTACAAATTTTTCTTTTATGGATTCTTCTGTGGATTATGCCTTTGGGATCA TGTCTAAGAACTCTACCAAATGTCATCAGGTACAAAGGTATTTTTCTGTTTTCTTCCAAA CATTTTATAGTTTTGTTTTACGTTTACATATGATTGGAGTTAATTGTGTACAATGTGAGG TTTAGGCCAAGGTTCCATTTCTACCATATGGATGACCAACTGCCCCACTGCTCTGTTGAA TGGACAATCCTTTCTCCACAGGGTTGCTTTTGTTTGCACTGCTGTCAAAGATCAAATGGC CCTATTTATGTGGGTCTGTTTCTAGACTCTCTGATCACTGACCCATCTGTCTGTTCTTTG CCAATACGACAGTCTTGATTTTTGTGGCTTTAAAGTCTGTTAAAACTGTGTAATGTGATT CATCTAACTTTTTTGTTCTTTTTAAAACATTGTTTTATCTATCCTTTTTACTGTTTTAGC TAGCTCCTTCACCATTCTGTATACATTTTAAAATCATCTTTTCTAAATCTAAAAAGAGTC CTACTGCAATGTTTTGGAATTTTGTTAATTTCACAGATCCTTCTGAGACTGGCATCTTAT GTTCAGTCTTCCAGTCTATGAGCGTGCTGTGTGCCGTCTCTCCACATACATAGTCTTTTT AGCATACAGATCCTGTTTTGTCTTGTTAGATTTATACCTCTCTCTCTCTCTCAGGAGCTA CTGTGTTTTTAACTTCAGTTTCCAATGTTTTATTGTCTATAGAAGTAAGATTTTTTTTTT TTTTTTGAGACAGTCTGGCTCTGTTGCCCAGGCTGGAGTGCAGTGACATGATCTCGGCTC ACTGCAACGTCTGCCTCACGGGTTCAAATGTGGCATGATCTCAGCTCACTGCAACCTCTG CCTCCCAGGTTCAAGCAATTCTCCTGTCTCAGCCTCCTGAGTAGCTGCGATTACAGGTGT GTGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGG TCAGGCTGATCTCCAACTCCTGACCTGGTGATACGCCTGCCTCAGCCTCCCAAAGAGCGT TGGGATTACAGGCATGAGCCACCACACCGGGTCTTTTATTTTTTTTGAGACAGAGTTCCA CTCTTGTTGCTCAGGCTGGAGTGCAATGGTGCGATCTCGGCTCACTGCAGCCTCTGCTTC CCGGATTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGTGCCCGCC ACCATGCCTGGATAGTTTTCCTATTTTTAGTAGACACAGGGTTTCACCATGTTGGTCAGC TGGTCTCAAACTCCTGACCTTAGGCCATCCACCAGCCTCGGCCTCAGCCTCCCAAAGTGC TGGGATTACAGGCATGAGCCACTGCACGCAGCCCTAAGATTAATTTGTATGTGTTACTGG TGAACATTCCAAACTCACTTACTGGCTCTACGAGGGTCTTTGTGGCAATCATTGCTGTTG CTTTAGATGAGTGTTCTCTATATAGACAATCATGTAGTCTGTGAATAAGGAAGTTTTATC TCACCTGTAATCCCAGCACTTTGGGAGGCTGAAGTGGGAAGATCACCTGAACCCAGGAGT TCAAGACCAGCCTGGGCAACATAGTGAGACCCCCCCGTATCGACTAAAAATACAAAAATT AGTCGGGCTGGTGGCACATGTCTGCAATCCCAGCTACTCTGGAGGCTGAGGCACATGCTC TCTGGAAGGAGGTGCCTGGGTGTGGCTCACCCTCCTCTTTTTCCCTGCTACCTAAAAGGA GGTCCCCAGGTGAAGCTCACTCACAACTCAGAAAGTTCAGGTCACCTCTGTGAGGGCATA TCTGCATACACTATTTGGACTCGGCTGGATGTGCATGCCTCTGGTCCCAGCTACTTGGGA GGCTGAGGTGGGACAACTGCCTGAGCCCAGGAGGTCCAGGCTGCAGCAAGGCAACAGCGC ACCATTGCACTCCAGCCTTCTGAATGACAGAGGAAGATCCTGCCTCAAAGAACAAATATT TGGACTCCTCCTGCATGGTCAATTGTCTCCTCTCTCCCATCTATTTATTAATTCAGTCTT TTATTTTGGAAATGGGATATTACTAGGCCTTGACTCCTGGGCTCAACTGATGCTCCCACC TCAGCCTCTGAGTAGCTGAACTACAGGTCCCACTCTGCCCAGCTCATTCAGTCACTTATT ACATCAGCAAAGACTCATCGATATTTCTTCAGCCCTGTGCATTATAATCCAATGCTACTT TATTCTGCTATTCAAGTTATTCCAGCCTCGCCCATTGGGACCCCTTGTCGCTGTGTCCCT TTGGCCCACAGTTGTGGGTTGTTTTTTTTGTTTTTTTGAGATGGAGTTTCACTCTTGCTG CCCAGGCTGGACTGCAATTGTGTGATCTCAGCTCACATCAACCTCCATCTCTCAGGTTCA AGGGATTCTCCTGCCTCAGCTTCCCCAGTAGCTGGGATTACAGACATGCGCCACCACACC TGGCTAATTTTGTATTTTTAGTAAAGACGGGGTTTCTCCACGTTGGTCAGACTGGTTTCC AACTCGCAAACCTCAAGTGATCCGCCCGCCTCTGCCTCCCAAAGTGCTGGGATTATAGGT GTGAGCCACCGCGCCCAGCCTGTGTTGTTTTTTAAATCATTTCCAGGCTCATGGTGTATA CCTTCTGCGCCAGTCCTAGGTGAATTTCTCCTGGTTGGTGAGTTTTCATTGTTTACCTCT GCTCACACAGGGACTCGAGGAGGGAGACTAGGACTCAGAGTCCTCCTTCATCTTGTCACT TCTCTAAACAATTACTTTTTGTTGAAGACGCCATGTAAGCTGGAATTCAAAGCCATCTCT TTGAACAACTGTGTGAAATAATCGTGCTAAACTGTTATTCTCCTTTAATCGTTCCAACCA AGCACCCACGGGGGCCATTATTCCTCTCCTACAACTGCAAGGCAGTGCCTCACCAACTAG CTTTGTTCCTGAGGCAAGCGGCAGGAACCCCTCTGCTTTCCTCAGTGAGCAAGCGGCCCC TGACCCTGGCGAGTGAGTTTTCTCTTCACAGCCCCCTGTCCCTGCTGCCCACTGAGCCAG CCAGCCCGAGGGTGGAAAAGTCATTCTGGCTCTAAGCTTCCAGCACAGTCCGGGAGACCA CACGGGTCCTGGGGAGGGTGGCTAAGCCCGAGGGGCTTTATAGGATGAGTCACAAGAAAG TCCATCTGGTGGGCCCTCCCTGACTCCCCTCCACTGTCCCCGGCTCACGGCGAGGAAGGC AAGGCTGGTGGGGGGGACAGGAAAGGGCTGGGGTCTCTCCCCACCTCCACTGCCAACGCC CTGCAGACCCCCAGGCCACAGCCTTTCCCGGGGCTCCCCCAAGGTATGGGAGGTGGGGCG GGTCCAGTTTACGCTGGTTTCAAAGAAGTGAGAGCGCCCCGCCGCCATGTCATGGAGGGT CCCGCGCCCCCACCCCTTGCCTGGGGTCGTGTGTGGGCAGCCGCAGAAAGCGCCCCGACG GCAGGAGCGGGGTTCCAGGCTGAGACCGGGCCTCGGCGGCGCCCCTTCCTGCCGGGAGTG GCGCATCCCAGGACCCACAGACAAACAGGGCCAGCCAGGGTCACCCGGAGCGCGAAGGCC GGCTATGGGCTTAGGGTGGGGTCTGGTCCCTACGGCCGGCCTAGGGGGAACGCGGGACAG GAGAAGGTCTGGGAAAAACCTGCTTCCGAGGCCTCGGCTTCGGGGCGTCCTCCTGAGCTG GCGCCAGCCCGCAGCGGGGCCGGGCAGGGACGCCGGCCTAACGGTGGGGACCGGCAGGGC CTGGGGGCAGGACGAGACAAGCACACAACCGACGGGGCGGGGCCAGGCGAGGGCACGGGG CCGAAGAAGCTTCTGCCAGGCCCGAGACCCGCACTTAGTTACCTGAGAAGGCGGGAAGGT GCGGCCGCGGGGTGAGCGGCGGACTGACCCAGCTCCAGCGCCTCTGCAGAGGCTTGCAAT bcftools-1.21/test/csq/EDUMMY0003/EDUMMY0003.fa.fai000066400000000000000000000000211467060157400206740ustar00rootroot000000000000004 76200 19 60 61 bcftools-1.21/test/csq/EDUMMY0003/EDUMMY0003.gff000066400000000000000000001114561467060157400203310ustar00rootroot000000000000004 GRCh37 chromosome -699436 190454839 . . . ID=chromosome:4;Alias=CM000666.1,NC_000004.11 4 ensembl_havana gene 100 64991 . + . ID=gene:ENSG00000185619;Name=PCGF3;biotype=protein_coding;description=polycomb group ring finger 3 [Source:HGNC Symbol%3BAcc:10066];gene_id=ENSG00000185619;logic_name=ensembl_havana_gene;version=13 4 ensembl_havana transcript 100 29295 . + . ID=transcript:ENST00000419774;Parent=gene:ENSG00000185619;Name=PCGF3-007;biotype=protein_coding;havana_transcript=OTTHUMT00000318558;havana_version=1;transcript_id=ENST00000419774;version=1 4 havana exon 100 322 . + . Parent=transcript:ENST00000419774;Name=ENSE00001798220;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001798220;rank=1;version=1 4 havana five_prime_UTR 100 322 . + . Parent=transcript:ENST00000419774 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000419774;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000419774 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000419774;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000419774 4 havana exon 26796 26850 . + . Parent=transcript:ENST00000419774;Name=ENSE00001744035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001744035;rank=4;version=1 4 havana five_prime_UTR 26796 26850 . + . Parent=transcript:ENST00000419774 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000419774 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000419774;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=5;version=1 4 havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000416279;Parent=transcript:ENST00000419774;protein_id=ENSP00000416279 4 havana exon 29283 29295 . + . Parent=transcript:ENST00000419774;Name=ENSE00001805037;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001805037;rank=6;version=1 4 havana CDS 29283 29295 . + 2 ID=CDS:ENSP00000416279;Parent=transcript:ENST00000419774;protein_id=ENSP00000416279 4 ensembl_havana transcript 117 64991 . + . ID=transcript:ENST00000362003;Parent=gene:ENSG00000185619;Name=PCGF3-001;biotype=protein_coding;ccdsid=CCDS3339.2;havana_transcript=OTTHUMT00000239197;havana_version=2;tag=basic;transcript_id=ENST00000362003;version=5 4 ensembl_havana exon 117 322 . + . Parent=transcript:ENST00000362003;Name=ENSE00001954691;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001954691;rank=1;version=1 4 ensembl_havana five_prime_UTR 117 322 . + . Parent=transcript:ENST00000362003 4 ensembl_havana exon 24982 25020 . + . Parent=transcript:ENST00000362003;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 ensembl_havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000362003 4 ensembl_havana exon 25322 25462 . + . Parent=transcript:ENST00000362003;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 ensembl_havana five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000362003 4 ensembl_havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000362003 4 ensembl_havana exon 28024 28141 . + . Parent=transcript:ENST00000362003;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=4;version=1 4 ensembl_havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 29283 29379 . + . Parent=transcript:ENST00000362003;Name=ENSE00003495438;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003495438;rank=5;version=1 4 ensembl_havana CDS 29283 29379 . + 2 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 31818 31873 . + . Parent=transcript:ENST00000362003;Name=ENSE00003654200;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003654200;rank=6;version=1 4 ensembl_havana CDS 31818 31873 . + 1 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 37825 37935 . + . Parent=transcript:ENST00000362003;Name=ENSE00003569995;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003569995;rank=7;version=1 4 ensembl_havana CDS 37825 37935 . + 2 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 38951 39039 . + . Parent=transcript:ENST00000362003;Name=ENSE00003580193;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003580193;rank=8;version=1 4 ensembl_havana CDS 38951 39039 . + 2 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 55630 55767 . + . Parent=transcript:ENST00000362003;Name=ENSE00003633495;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003633495;rank=9;version=1 4 ensembl_havana CDS 55630 55767 . + 0 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 59335 59415 . + . Parent=transcript:ENST00000362003;Name=ENSE00003669111;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003669111;rank=10;version=1 4 ensembl_havana CDS 59335 59415 . + 0 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana CDS 60383 60430 . + 0 ID=CDS:ENSP00000354724;Parent=transcript:ENST00000362003;protein_id=ENSP00000354724 4 ensembl_havana exon 60383 64991 . + . Parent=transcript:ENST00000362003;Name=ENSE00001313124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001313124;rank=11;version=3 4 ensembl_havana three_prime_UTR 60431 64991 . + . Parent=transcript:ENST00000362003 4 ensembl_havana aberrant_processed_transcript 134 25697 . + . ID=transcript:ENST00000475288;Parent=gene:ENSG00000185619;Name=PCGF3-006;biotype=retained_intron;havana_transcript=OTTHUMT00000318557;havana_version=1;transcript_id=ENST00000475288;version=1 4 havana exon 134 322 . + . Parent=transcript:ENST00000475288;Name=ENSE00001822593;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001822593;rank=1;version=1 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000475288;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana exon 25322 25697 . + . Parent=transcript:ENST00000475288;Name=ENSE00001841909;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001841909;rank=3;version=1 4 ensembl_havana transcript 136 28831 . + . ID=transcript:ENST00000400151;Parent=gene:ENSG00000185619;Name=PCGF3-009;biotype=protein_coding;havana_transcript=OTTHUMT00000318560;havana_version=1;tag=basic;transcript_id=ENST00000400151;version=2 4 havana exon 136 322 . + . Parent=transcript:ENST00000400151;Name=ENSE00001435879;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001435879;rank=1;version=3 4 havana five_prime_UTR 136 322 . + . Parent=transcript:ENST00000400151 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000400151;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000400151 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000400151;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000400151 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000400151 4 havana exon 28024 28831 . + . Parent=transcript:ENST00000400151;Name=ENSE00001556838;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001556838;rank=4;version=1 4 havana CDS 28033 28554 . + 0 ID=CDS:ENSP00000383015;Parent=transcript:ENST00000400151;protein_id=ENSP00000383015 4 havana three_prime_UTR 28555 28831 . + . Parent=transcript:ENST00000400151 4 ensembl_havana processed_transcript 136 29194 . + . ID=transcript:ENST00000482726;Parent=gene:ENSG00000185619;Name=PCGF3-008;biotype=processed_transcript;havana_transcript=OTTHUMT00000318559;havana_version=1;transcript_id=ENST00000482726;version=1 4 havana exon 136 322 . + . Parent=transcript:ENST00000482726;Name=ENSE00001435879;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001435879;rank=1;version=3 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000482726;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000482726;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000482726;Name=ENSE00003502443;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003502443;rank=4;version=1 4 havana exon 29142 29194 . + . Parent=transcript:ENST00000482726;Name=ENSE00001821668;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001821668;rank=5;version=1 4 ensembl_havana transcript 136 29361 . + . ID=transcript:ENST00000427463;Parent=gene:ENSG00000185619;Name=PCGF3-012;biotype=protein_coding;havana_transcript=OTTHUMT00000318563;havana_version=1;transcript_id=ENST00000427463;version=1 4 havana exon 136 322 . + . Parent=transcript:ENST00000427463;Name=ENSE00001435879;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001435879;rank=1;version=3 4 havana five_prime_UTR 136 322 . + . Parent=transcript:ENST00000427463 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000427463;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000427463 4 havana exon 25304 25462 . + . Parent=transcript:ENST00000427463;Name=ENSE00001748695;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001748695;rank=3;version=1 4 havana five_prime_UTR 25304 25462 . + . Parent=transcript:ENST00000427463 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000427463 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000427463;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=4;version=1 4 havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000401431;Parent=transcript:ENST00000427463;protein_id=ENSP00000401431 4 havana exon 29283 29361 . + . Parent=transcript:ENST00000427463;Name=ENSE00001648161;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001648161;rank=5;version=1 4 havana CDS 29283 29361 . + 2 ID=CDS:ENSP00000401431;Parent=transcript:ENST00000427463;protein_id=ENSP00000401431 4 ensembl_havana transcript 136 60959 . + . ID=transcript:ENST00000470161;Parent=gene:ENSG00000185619;Name=PCGF3-004;biotype=protein_coding;ccdsid=CCDS3339.2;havana_transcript=OTTHUMT00000318555;havana_version=1;tag=basic;transcript_id=ENST00000470161;version=2 4 havana exon 136 322 . + . Parent=transcript:ENST00000470161;Name=ENSE00001435879;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001435879;rank=1;version=3 4 havana five_prime_UTR 136 322 . + . Parent=transcript:ENST00000470161 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000470161;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000470161 4 havana exon 25304 25462 . + . Parent=transcript:ENST00000470161;Name=ENSE00001748695;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001748695;rank=3;version=1 4 havana five_prime_UTR 25304 25462 . + . Parent=transcript:ENST00000470161 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000470161 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000470161;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=4;version=1 4 havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 29283 29379 . + . Parent=transcript:ENST00000470161;Name=ENSE00003495438;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003495438;rank=5;version=1 4 havana CDS 29283 29379 . + 2 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 31818 31873 . + . Parent=transcript:ENST00000470161;Name=ENSE00003654200;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003654200;rank=6;version=1 4 havana CDS 31818 31873 . + 1 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 37825 37935 . + . Parent=transcript:ENST00000470161;Name=ENSE00003569995;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003569995;rank=7;version=1 4 havana CDS 37825 37935 . + 2 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 38951 39039 . + . Parent=transcript:ENST00000470161;Name=ENSE00003580193;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003580193;rank=8;version=1 4 havana CDS 38951 39039 . + 2 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 55630 55767 . + . Parent=transcript:ENST00000470161;Name=ENSE00003633495;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003633495;rank=9;version=1 4 havana CDS 55630 55767 . + 0 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 59335 59415 . + . Parent=transcript:ENST00000470161;Name=ENSE00003669111;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003669111;rank=10;version=1 4 havana CDS 59335 59415 . + 0 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana CDS 60383 60430 . + 0 ID=CDS:ENSP00000420489;Parent=transcript:ENST00000470161;protein_id=ENSP00000420489 4 havana exon 60383 60959 . + . Parent=transcript:ENST00000470161;Name=ENSE00001953386;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001953386;rank=11;version=1 4 havana three_prime_UTR 60431 60959 . + . Parent=transcript:ENST00000470161 4 ensembl_havana NMD_transcript_variant 184 60950 . + . ID=transcript:ENST00000430644;Parent=gene:ENSG00000185619;Name=PCGF3-003;biotype=nonsense_mediated_decay;havana_transcript=OTTHUMT00000318554;havana_version=1;transcript_id=ENST00000430644;version=1 4 havana exon 184 322 . + . Parent=transcript:ENST00000430644;Name=ENSE00001602502;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001602502;rank=1;version=1 4 havana five_prime_UTR 184 322 . + . Parent=transcript:ENST00000430644 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000430644;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000430644 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000430644;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000430644 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000430644 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000430644;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=4;version=1 4 havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000402946;Parent=transcript:ENST00000430644;protein_id=ENSP00000402946 4 havana CDS 28236 28471 . + 2 ID=CDS:ENSP00000402946;Parent=transcript:ENST00000430644;protein_id=ENSP00000402946 4 havana exon 28236 29379 . + . Parent=transcript:ENST00000430644;Name=ENSE00003625869;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003625869;rank=5;version=1 4 havana three_prime_UTR 28472 29379 . + . Parent=transcript:ENST00000430644 4 havana exon 31818 31873 . + . Parent=transcript:ENST00000430644;Name=ENSE00003652038;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003652038;rank=6;version=1 4 havana three_prime_UTR 31818 31873 . + . Parent=transcript:ENST00000430644 4 havana exon 37825 37935 . + . Parent=transcript:ENST00000430644;Name=ENSE00003540668;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003540668;rank=7;version=1 4 havana three_prime_UTR 37825 37935 . + . Parent=transcript:ENST00000430644 4 havana exon 38951 39039 . + . Parent=transcript:ENST00000430644;Name=ENSE00003527077;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003527077;rank=8;version=1 4 havana three_prime_UTR 38951 39039 . + . Parent=transcript:ENST00000430644 4 havana exon 55630 55767 . + . Parent=transcript:ENST00000430644;Name=ENSE00003639287;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003639287;rank=9;version=1 4 havana three_prime_UTR 55630 55767 . + . Parent=transcript:ENST00000430644 4 havana exon 59335 59415 . + . Parent=transcript:ENST00000430644;Name=ENSE00003481183;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003481183;rank=10;version=1 4 havana three_prime_UTR 59335 59415 . + . Parent=transcript:ENST00000430644 4 havana exon 60386 60950 . + . Parent=transcript:ENST00000430644;Name=ENSE00001647245;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001647245;rank=11;version=1 4 havana three_prime_UTR 60386 60950 . + . Parent=transcript:ENST00000430644 4 ensembl_havana aberrant_processed_transcript 227 31892 . + . ID=transcript:ENST00000484141;Parent=gene:ENSG00000185619;Name=PCGF3-011;biotype=retained_intron;havana_transcript=OTTHUMT00000318562;havana_version=1;transcript_id=ENST00000484141;version=1 4 havana exon 227 322 . + . Parent=transcript:ENST00000484141;Name=ENSE00001875286;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001875286;rank=1;version=1 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000484141;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000484141;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000484141;Name=ENSE00003502443;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003502443;rank=4;version=1 4 havana exon 29283 29379 . + . Parent=transcript:ENST00000484141;Name=ENSE00003590904;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003590904;rank=5;version=1 4 havana exon 31818 31892 . + . Parent=transcript:ENST00000484141;Name=ENSE00001843601;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001843601;rank=6;version=1 4 ensembl_havana NMD_transcript_variant 295 62215 . + . ID=transcript:ENST00000440452;Parent=gene:ENSG00000185619;Name=PCGF3-002;biotype=nonsense_mediated_decay;havana_transcript=OTTHUMT00000318553;havana_version=1;transcript_id=ENST00000440452;version=1 4 havana exon 295 322 . + . Parent=transcript:ENST00000440452;Name=ENSE00001618190;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001618190;rank=1;version=1 4 havana five_prime_UTR 295 322 . + . Parent=transcript:ENST00000440452 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000440452;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000440452 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000440452;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000440452 4 havana exon 26752 26850 . + . Parent=transcript:ENST00000440452;Name=ENSE00001791347;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001791347;rank=4;version=1 4 havana five_prime_UTR 26752 26850 . + . Parent=transcript:ENST00000440452 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000440452 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000440452;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=5;version=1 4 havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000405840;Parent=transcript:ENST00000440452;protein_id=ENSP00000405840 4 havana CDS 28236 28471 . + 2 ID=CDS:ENSP00000405840;Parent=transcript:ENST00000440452;protein_id=ENSP00000405840 4 havana exon 28236 29379 . + . Parent=transcript:ENST00000440452;Name=ENSE00003625869;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003625869;rank=6;version=1 4 havana three_prime_UTR 28472 29379 . + . Parent=transcript:ENST00000440452 4 havana exon 31818 31873 . + . Parent=transcript:ENST00000440452;Name=ENSE00003652038;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003652038;rank=7;version=1 4 havana three_prime_UTR 31818 31873 . + . Parent=transcript:ENST00000440452 4 havana exon 37825 37935 . + . Parent=transcript:ENST00000440452;Name=ENSE00003540668;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003540668;rank=8;version=1 4 havana three_prime_UTR 37825 37935 . + . Parent=transcript:ENST00000440452 4 havana exon 38951 39039 . + . Parent=transcript:ENST00000440452;Name=ENSE00003527077;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003527077;rank=9;version=1 4 havana three_prime_UTR 38951 39039 . + . Parent=transcript:ENST00000440452 4 havana exon 55630 55767 . + . Parent=transcript:ENST00000440452;Name=ENSE00003639287;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003639287;rank=10;version=1 4 havana three_prime_UTR 55630 55767 . + . Parent=transcript:ENST00000440452 4 havana exon 59335 59415 . + . Parent=transcript:ENST00000440452;Name=ENSE00003481183;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003481183;rank=11;version=1 4 havana three_prime_UTR 59335 59415 . + . Parent=transcript:ENST00000440452 4 havana exon 60383 60756 . + . Parent=transcript:ENST00000440452;Name=ENSE00003631453;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003631453;rank=12;version=1 4 havana three_prime_UTR 60383 60756 . + . Parent=transcript:ENST00000440452 4 havana exon 61025 62215 . + . Parent=transcript:ENST00000440452;Name=ENSE00001640651;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001640651;rank=13;version=1 4 havana three_prime_UTR 61025 62215 . + . Parent=transcript:ENST00000440452 4 ensembl_havana transcript 295 62215 . + . ID=transcript:ENST00000521023;Parent=gene:ENSG00000185619;Name=PCGF3-202;biotype=protein_coding;tag=basic;transcript_id=ENST00000521023;version=2 4 ensembl exon 295 322 . + . Parent=transcript:ENST00000521023;Name=ENSE00001618190;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001618190;rank=1;version=1 4 ensembl five_prime_UTR 295 322 . + . Parent=transcript:ENST00000521023 4 ensembl exon 24982 25020 . + . Parent=transcript:ENST00000521023;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 ensembl five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000521023 4 ensembl exon 25322 25462 . + . Parent=transcript:ENST00000521023;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 ensembl five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000521023 4 ensembl exon 26752 26850 . + . Parent=transcript:ENST00000521023;Name=ENSE00001791347;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001791347;rank=4;version=1 4 ensembl five_prime_UTR 26752 26850 . + . Parent=transcript:ENST00000521023 4 ensembl exon 28024 28141 . + . Parent=transcript:ENST00000521023;Name=ENSE00003502443;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003502443;rank=5;version=1 4 ensembl five_prime_UTR 28024 28141 . + . Parent=transcript:ENST00000521023 4 ensembl five_prime_UTR 28236 29275 . + . Parent=transcript:ENST00000521023 4 ensembl exon 28236 29379 . + . Parent=transcript:ENST00000521023;Name=ENSE00003689794;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00003689794;rank=6;version=1 4 ensembl CDS 29276 29379 . + 0 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl exon 31818 31873 . + . Parent=transcript:ENST00000521023;Name=ENSE00003654200;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003654200;rank=7;version=1 4 ensembl CDS 31818 31873 . + 1 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl exon 37825 37935 . + . Parent=transcript:ENST00000521023;Name=ENSE00003569995;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003569995;rank=8;version=1 4 ensembl CDS 37825 37935 . + 2 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl exon 38951 39039 . + . Parent=transcript:ENST00000521023;Name=ENSE00003580193;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003580193;rank=9;version=1 4 ensembl CDS 38951 39039 . + 2 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl exon 55630 55767 . + . Parent=transcript:ENST00000521023;Name=ENSE00003633495;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003633495;rank=10;version=1 4 ensembl CDS 55630 55767 . + 0 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl exon 59335 59415 . + . Parent=transcript:ENST00000521023;Name=ENSE00003669111;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003669111;rank=11;version=1 4 ensembl CDS 59335 59415 . + 0 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl CDS 60383 60430 . + 0 ID=CDS:ENSP00000430393;Parent=transcript:ENST00000521023;protein_id=ENSP00000430393 4 ensembl exon 60383 60756 . + . Parent=transcript:ENST00000521023;Name=ENSE00003465123;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003465123;rank=12;version=1 4 ensembl three_prime_UTR 60431 60756 . + . Parent=transcript:ENST00000521023 4 ensembl exon 61025 62215 . + . Parent=transcript:ENST00000521023;Name=ENSE00001640651;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001640651;rank=13;version=1 4 ensembl three_prime_UTR 61025 62215 . + . Parent=transcript:ENST00000521023 4 ensembl_havana transcript 19459 37889 . + . ID=transcript:ENST00000433814;Parent=gene:ENSG00000185619;Name=PCGF3-005;biotype=protein_coding;havana_transcript=OTTHUMT00000318556;havana_version=1;transcript_id=ENST00000433814;version=1 4 havana exon 19459 19581 . + . Parent=transcript:ENST00000433814;Name=ENSE00001786619;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001786619;rank=1;version=1 4 havana five_prime_UTR 19459 19581 . + . Parent=transcript:ENST00000433814 4 havana exon 24982 25020 . + . Parent=transcript:ENST00000433814;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana five_prime_UTR 24982 25020 . + . Parent=transcript:ENST00000433814 4 havana exon 25322 25462 . + . Parent=transcript:ENST00000433814;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana five_prime_UTR 25322 25462 . + . Parent=transcript:ENST00000433814 4 havana five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000433814 4 havana exon 28024 28141 . + . Parent=transcript:ENST00000433814;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=4;version=1 4 havana CDS 28033 28141 . + 0 ID=CDS:ENSP00000398493;Parent=transcript:ENST00000433814;protein_id=ENSP00000398493 4 havana exon 29283 29379 . + . Parent=transcript:ENST00000433814;Name=ENSE00003495438;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003495438;rank=5;version=1 4 havana CDS 29283 29379 . + 2 ID=CDS:ENSP00000398493;Parent=transcript:ENST00000433814;protein_id=ENSP00000398493 4 havana exon 31818 31873 . + . Parent=transcript:ENST00000433814;Name=ENSE00003654200;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003654200;rank=6;version=1 4 havana CDS 31818 31873 . + 1 ID=CDS:ENSP00000398493;Parent=transcript:ENST00000433814;protein_id=ENSP00000398493 4 havana exon 37825 37889 . + . Parent=transcript:ENST00000433814;Name=ENSE00001704961;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001704961;rank=7;version=1 4 havana CDS 37825 37889 . + 2 ID=CDS:ENSP00000398493;Parent=transcript:ENST00000433814;protein_id=ENSP00000398493 4 ensembl_havana transcript 25428 61382 . + . ID=transcript:ENST00000505655;Parent=gene:ENSG00000185619;Name=PCGF3-201;biotype=protein_coding;ccdsid=CCDS3339.2;tag=basic;transcript_id=ENST00000505655;version=2 4 ensembl exon 25428 25462 . + . Parent=transcript:ENST00000505655;Name=ENSE00002290053;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002290053;rank=1;version=1 4 ensembl five_prime_UTR 25428 25462 . + . Parent=transcript:ENST00000505655 4 ensembl five_prime_UTR 28024 28032 . + . Parent=transcript:ENST00000505655 4 ensembl exon 28024 28141 . + . Parent=transcript:ENST00000505655;Name=ENSE00003543410;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003543410;rank=2;version=1 4 ensembl CDS 28033 28141 . + 0 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 29283 29379 . + . Parent=transcript:ENST00000505655;Name=ENSE00003495438;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003495438;rank=3;version=1 4 ensembl CDS 29283 29379 . + 2 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 31818 31873 . + . Parent=transcript:ENST00000505655;Name=ENSE00003654200;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003654200;rank=4;version=1 4 ensembl CDS 31818 31873 . + 1 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 37825 37935 . + . Parent=transcript:ENST00000505655;Name=ENSE00003569995;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003569995;rank=5;version=1 4 ensembl CDS 37825 37935 . + 2 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 38951 39039 . + . Parent=transcript:ENST00000505655;Name=ENSE00003580193;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003580193;rank=6;version=1 4 ensembl CDS 38951 39039 . + 2 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 55630 55767 . + . Parent=transcript:ENST00000505655;Name=ENSE00003633495;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003633495;rank=7;version=1 4 ensembl CDS 55630 55767 . + 0 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 59335 59415 . + . Parent=transcript:ENST00000505655;Name=ENSE00003669111;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003669111;rank=8;version=1 4 ensembl CDS 59335 59415 . + 0 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl CDS 60383 60430 . + 0 ID=CDS:ENSP00000423393;Parent=transcript:ENST00000505655;protein_id=ENSP00000423393 4 ensembl exon 60383 61382 . + . Parent=transcript:ENST00000505655;Name=ENSE00002276460;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002276460;rank=9;version=1 4 ensembl three_prime_UTR 60431 61382 . + . Parent=transcript:ENST00000505655 4 ensembl_havana processed_transcript 38216 55715 . + . ID=transcript:ENST00000488032;Parent=gene:ENSG00000185619;Name=PCGF3-010;biotype=processed_transcript;havana_transcript=OTTHUMT00000318561;havana_version=1;transcript_id=ENST00000488032;version=1 4 havana exon 38216 38303 . + . Parent=transcript:ENST00000488032;Name=ENSE00001877648;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001877648;rank=1;version=1 4 havana exon 38951 39039 . + . Parent=transcript:ENST00000488032;Name=ENSE00003527077;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003527077;rank=2;version=1 4 havana exon 55630 55715 . + . Parent=transcript:ENST00000488032;Name=ENSE00001838583;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001838583;rank=3;version=1 4 havana gene 16627 18386 . - . ID=gene:ENSG00000248416;Name=RP11-1191J2.4;biotype=antisense;gene_id=ENSG00000248416;logic_name=havana;version=1 4 havana transcript 16627 18386 . - . ID=transcript:ENST00000502923;Parent=gene:ENSG00000248416;Name=RP11-1191J2.4-001;biotype=antisense;havana_transcript=OTTHUMT00000358569;havana_version=1;tag=basic;transcript_id=ENST00000502923;version=1 4 havana exon 16627 16789 . - . Parent=transcript:ENST00000502923;Name=ENSE00002086013;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002086013;rank=2;version=1 4 havana exon 17981 18386 . - . Parent=transcript:ENST00000502923;Name=ENSE00002075629;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002075629;rank=1;version=1 4 havana gene 51373 52091 . - . ID=gene:ENSG00000272588;Name=RP11-440L14.4;biotype=antisense;gene_id=ENSG00000272588;logic_name=havana;version=1 4 havana transcript 51373 52091 . - . ID=transcript:ENST00000607877;Parent=gene:ENSG00000272588;Name=RP11-440L14.4-001;biotype=antisense;havana_transcript=OTTHUMT00000472434;havana_version=1;tag=basic;transcript_id=ENST00000607877;version=1 4 havana exon 51373 52091 . - . Parent=transcript:ENST00000607877;Name=ENSE00003702866;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003702866;rank=1;version=1 4 havana gene 56738 76200 . - . ID=gene:ENSG00000249592;Name=RP11-440L14.1;biotype=antisense;gene_id=ENSG00000249592;logic_name=havana;version=1 4 havana transcript 56738 76200 . - . ID=transcript:ENST00000503571;Parent=gene:ENSG00000249592;Name=RP11-440L14.1-001;biotype=antisense;havana_transcript=OTTHUMT00000358826;havana_version=1;tag=basic;transcript_id=ENST00000503571;version=1 4 havana exon 56738 57190 . - . Parent=transcript:ENST00000503571;Name=ENSE00002040693;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002040693;rank=2;version=1 4 havana exon 76123 76200 . - . Parent=transcript:ENST00000503571;Name=ENSE00002070357;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002070357;rank=1;version=1 4 havana transcript 61492 76181 . - . ID=transcript:ENST00000507446;Parent=gene:ENSG00000249592;Name=RP11-440L14.1-002;biotype=antisense;havana_transcript=OTTHUMT00000358827;havana_version=1;tag=basic;transcript_id=ENST00000507446;version=1 4 havana exon 61492 61966 . - . Parent=transcript:ENST00000507446;Name=ENSE00002038807;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002038807;rank=2;version=1 4 havana exon 76123 76181 . - . Parent=transcript:ENST00000507446;Name=ENSE00002030658;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002030658;rank=1;version=1 4 havana transcript 74500 76200 . - . ID=transcript:ENST00000503185;Parent=gene:ENSG00000249592;Name=RP11-440L14.1-003;biotype=antisense;havana_transcript=OTTHUMT00000358828;havana_version=1;tag=basic;transcript_id=ENST00000503185;version=1 4 havana exon 74500 75039 . - . Parent=transcript:ENST00000503185;Name=ENSE00002062283;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002062283;rank=2;version=1 4 havana exon 76123 76200 . - . Parent=transcript:ENST00000503185;Name=ENSE00002070357;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002070357;rank=1;version=1 4 havana transcript 74597 76200 . - . ID=transcript:ENST00000503405;Parent=gene:ENSG00000249592;Name=RP11-440L14.1-004;biotype=antisense;havana_transcript=OTTHUMT00000358829;havana_version=1;tag=basic;transcript_id=ENST00000503405;version=1 4 havana exon 74597 75068 . - . Parent=transcript:ENST00000503405;Name=ENSE00002048175;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002048175;rank=2;version=1 4 havana exon 76123 76200 . - . Parent=transcript:ENST00000503405;Name=ENSE00002070357;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002070357;rank=1;version=1 4 havana gene 58838 59425 . - . ID=gene:ENSG00000233799;Name=AC139887.4;biotype=antisense;gene_id=ENSG00000233799;logic_name=havana;version=1 4 havana transcript 58838 59425 . - . ID=transcript:ENST00000454037;Parent=gene:ENSG00000233799;Name=AC139887.4-001;biotype=antisense;havana_transcript=OTTHUMT00000318552;havana_version=1;tag=basic;transcript_id=ENST00000454037;version=1 4 havana exon 58838 58960 . - . Parent=transcript:ENST00000454037;Name=ENSE00001770320;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001770320;rank=2;version=1 4 havana exon 59263 59425 . - . Parent=transcript:ENST00000454037;Name=ENSE00001679434;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001679434;rank=1;version=1 bcftools-1.21/test/csq/EDUMMY0003/long-del.txt000066400000000000000000000010711467060157400205730ustar00rootroot0000000000000028503 TTCACACCTGATGTGCGTCC T 3_prime_utr|PCGF3|ENST00000430644|NMD,3_prime_utr|PCGF3|ENST00000440452|NMD,5_prime_utr|PCGF3|ENST00000521023|protein_coding,frameshift|PCGF3|ENST00000400151|protein_coding|+|157SSHLMCVLTPDESVLWC*>157SSHLMSLCFGV|28503TTCACACCTGATGTGCGTCC>T 28503 TTCACACCTGATGTGCGTCC T 3_prime_utr&NMD_transcript|PCGF3|ENST00000430644|NMD,3_prime_utr&NMD_transcript|PCGF3|ENST00000440452|NMD,5_prime_utr|PCGF3|ENST00000521023|protein_coding,frameshift|PCGF3|ENST00000400151|protein_coding|+|157SSHLMCVLTPDESVLWC*>157SSHLMSLCFGV|28503TTCACACCTGATGTGCGTCC>T bcftools-1.21/test/csq/EDUMMY0003/long-del.vcf000066400000000000000000000011161467060157400205320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 4 28503 . TTCACACCTGATGTGCGTCC T . PASS EXP=5_prime_utr|PCGF3|ENST00000521023|protein_coding,3_prime_utr|PCGF3|ENST00000430644|NMD,3_prime_utr|PCGF3|ENST00000440452|NMD,frameshift|PCGF3|ENST00000400151|protein_coding|+|157SSHLMCVLTPDESVLWC*>157SSHLMSLCFGV|28503TTCACACCTGATGTGCGTCC>T bcftools-1.21/test/csq/EMN908947/000077500000000000000000000000001467060157400161535ustar00rootroot00000000000000bcftools-1.21/test/csq/EMN908947/EMN908947.fa000066400000000000000000000733331467060157400176200ustar00rootroot00000000000000>MN908947.3 Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome ATTAAAGGTTTATACCTTCCCAGGTAACAAACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAA CGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAAC TAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTG TTGCAGCCGATCATCAGCACATCTAGGTTTCGTCCGGGTGTGACCGAAAGGTAAGATGGAGAGCCTTGTC CCTGGTTTCAACGAGAAAACACACGTCCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTAC GTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGG CTTAGTAGAAGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAAACGTTCGGAT GCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTCAGTACGGTC GTAGTGGTGAGACACTTGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCT TCTTCGTAAGAACGGTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTA GGCGACGAGCTTGGCACTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTG TTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGG CCCTGATGGCTACCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTTCATGCACTTTG TCCGAACAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTG CTTGGTACACGGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTTTTGAAATTAAATTGGCAAAGAA ATTTGACACCTTCAATGGGGAATGTCCAAATTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAA CCAAGGGTTGAAAAGAAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCAC CAAATGAATGCAACCAAATGTGCCTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCA GACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGAAGGTGCCACT ACTTGTGGTTACTTACCCCAAAATGCTGTTGTTAAAATTTATTGTCCAGCATGTCACAATTCAGAAGTAG GACCTGAGCATAGTCTTGCCGAATACCATAATGAATCTGGCTTGAAAACCATTCTTCGTAAGGGTGGTCG CACTATTGCCTTTGGAGGCTGTGTGTTCTCTTATGTTGGTTGCCATAACAAGTGTGCCTATTGGGTTCCA CGTGCTAGCGCTAACATAGGTTGTAACCATACAGGTGTTGTTGGAGAAGGTTCCGAAGGTCTTAATGACA ACCTTCTTGAAATACTCCAAAAAGAGAAAGTCAACATCAATATTGTTGGTGACTTTAAACTTAATGAAGA GATCGCCATTATTTTGGCATCTTTTTCTGCTTCCACAAGTGCTTTTGTGGAAACTGTGAAAGGTTTGGAT TATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTTAAAGTTACAAAAGGAAAAGCTAAAAAAG GTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTTATGCATTTGCATCAGAGGCTGCTCG TGTTGTACGATCAATTTTCTCCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAGGCC GCTATAACAATACTAGATGGAATTTCACAGTATTCACTGAGACTCATTGATGCTATGATGTTCACATCTG ATTTGGCTACTAACAATCTAGTTGTAATGGCCTACATTACAGGTGGTGTTGTTCAGTTGACTTCGCAGTG GCTAACTAACATCTTTGGCACTGTTTATGAAAAACTCAAACCCGTCCTTGATTGGCTTGAAGAGAAGTTT AAGGAAGGTGTAGAGTTTCTTAGAGACGGTTGGGAAATTGTTAAATTTATCTCAACCTGTGCTTGTGAAA TTGTCGGTGGACAAATTGTCACCTGTGCAAAGGAAATTAAGGAGAGTGTTCAGACATTCTTTAAGCTTGT AAATAAATTTTTGGCTTTGTGTGCTGACTCTATCATTATTGGTGGAGCTAAACTTAAAGCCTTGAATTTA GGTGAAACATTTGTCACGCACTCAAAGGGATTGTACAGAAAGTGTGTTAAATCCAGAGAAGAAACTGGCC TACTCATGCCTCTAAAAGCCCCAAAAGAAATTATCTTCTTAGAGGGAGAAACACTTCCCACAGAAGTGTT AACAGAGGAAGTTGTCTTGAAAACTGGTGATTTACAACCATTAGAACAACCTACTAGTGAAGCTGTTGAA GCTCCATTGGTTGGTACACCAGTTTGTATTAACGGGCTTATGTTGCTCGAAATCAAAGACACAGAAAAGT ACTGTGCCCTTGCACCTAATATGATGGTAACAAACAATACCTTCACACTCAAAGGCGGTGCACCAACAAA GGTTACTTTTGGTGATGACACTGTGATAGAAGTGCAAGGTTACAAGAGTGTGAATATCACTTTTGAACTT GATGAAAGGATTGATAAAGTACTTAATGAGAAGTGCTCTGCCTATACAGTTGAACTCGGTACAGAAGTAA ATGAGTTCGCCTGTGTTGTGGCAGATGCTGTCATAAAAACTTTGCAACCAGTATCTGAATTACTTACACC ACTGGGCATTGATTTAGATGAGTGGAGTATGGCTACATACTACTTATTTGATGAGTCTGGTGAGTTTAAA TTGGCTTCACATATGTATTGTTCTTTCTACCCTCCAGATGAGGATGAAGAAGAAGGTGATTGTGAAGAAG AAGAGTTTGAGCCATCAACTCAATATGAGTATGGTACTGAAGATGATTACCAAGGTAAACCTTTGGAATT TGGTGCCACTTCTGCTGCTCTTCAACCTGAAGAAGAGCAAGAAGAAGATTGGTTAGATGATGATAGTCAA CAAACTGTTGGTCAACAAGACGGCAGTGAGGACAATCAGACAACTACTATTCAAACAATTGTTGAGGTTC AACCTCAATTAGAGATGGAACTTACACCAGTTGTTCAGACTATTGAAGTGAATAGTTTTAGTGGTTATTT AAAACTTACTGACAATGTATACATTAAAAATGCAGACATTGTGGAAGAAGCTAAAAAGGTAAAACCAACA GTGGTTGTTAATGCAGCCAATGTTTACCTTAAACATGGAGGAGGTGTTGCAGGAGCCTTAAATAAGGCTA CTAACAATGCCATGCAAGTTGAATCTGATGATTACATAGCTACTAATGGACCACTTAAAGTGGGTGGTAG TTGTGTTTTAAGCGGACACAATCTTGCTAAACACTGTCTTCATGTTGTCGGCCCAAATGTTAACAAAGGT GAAGACATTCAACTTCTTAAGAGTGCTTATGAAAATTTTAATCAGCACGAAGTTCTACTTGCACCATTAT TATCAGCTGGTATTTTTGGTGCTGACCCTATACATTCTTTAAGAGTTTGTGTAGATACTGTTCGCACAAA TGTCTACTTAGCTGTCTTTGATAAAAATCTCTATGACAAACTTGTTTCAAGCTTTTTGGAAATGAAGAGT GAAAAGCAAGTTGAACAAAAGATCGCTGAGATTCCTAAAGAGGAAGTTAAGCCATTTATAACTGAAAGTA AACCTTCAGTTGAACAGAGAAAACAAGATGATAAGAAAATCAAAGCTTGTGTTGAAGAAGTTACAACAAC TCTGGAAGAAACTAAGTTCCTCACAGAAAACTTGTTACTTTATATTGACATTAATGGCAATCTTCATCCA GATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTG ATGTTGTTCAAGAGGGTGTTTTAACTGCTGTGGTTATACCTACTAAAAAGGCTGGTGGCACTACTGAAAT GCTAGCGAAAGCTTTGAGAAAAGTGCCAACAGACAATTATATAACCACTTACCCGGGTCAGGGTTTAAAT GGTTACACTGTAGAGGAGGCAAAGACAGTGCTTAAAAAGTGTAAAAGTGCCTTTTACATTCTACCATCTA TTATCTCTAATGAGAAGCAAGAAATTCTTGGAACTGTTTCTTGGAATTTGCGAGAAATGCTTGCACATGC AGAAGAAACACGCAAATTAATGCCTGTCTGTGTGGAAACTAAAGCCATAGTTTCAACTATACAGCGTAAA TATAAGGGTATTAAAATACAAGAGGGTGTGGTTGATTATGGTGCTAGATTTTACTTTTACACCAGTAAAA CAACTGTAGCGTCACTTATCAACACACTTAACGATCTAAATGAAACTCTTGTTACAATGCCACTTGGCTA TGTAACACATGGCTTAAATTTGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAGTGCCAGCTACAGTT TCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTCTTCTTCTAAAACACCTGAAG AACATTTTATTGAAACCATCTCACTTGCTGGTTCCTATAAAGATTGGTCCTATTCTGGACAATCTACACA ACTAGGTATAGAATTTCTTAAGAGAGGTGATAAAAGTGTATATTACACTAGTAATCCTACCACATTCCAC CTAGATGGTGAAGTTATCACCTTTGACAATCTTAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTA AGGTGTTTACAACAGTAGACAACATTAACCTCCACACGCAAGTTGTGGACATGTCAATGACATATGGACA ACAGTTTGGTCCAACTTATTTGGATGGAGCTGATGTTACTAAAATAAAACCTCATAATTCACATGAAGGT AAAACATTTTATGTTTTACCTAATGATGACACTCTACGTGTTGAGGCTTTTGAGTACTACCACACAACTG ATCCTAGTTTTCTGGGTAGGTACATGTCAGCATTAAATCACACTAAAAAGTGGAAATACCCACAAGTTAA TGGTTTAACTTCTATTAAATGGGCAGATAACAACTGTTATCTTGCCACTGCATTGTTAACACTCCAACAA ATAGAGTTGAAGTTTAATCCACCTGCTCTACAAGATGCTTATTACAGAGCAAGGGCTGGTGAAGCTGCTA ACTTTTGTGCACTTATCTTAGCCTACTGTAATAAGACAGTAGGTGAGTTAGGTGATGTTAGAGAAACAAT GAGTTACTTGTTTCAACATGCCAATTTAGATTCTTGCAAAAGAGTCTTGAACGTGGTGTGTAAAACTTGT GGACAACAGCAGACAACCCTTAAGGGTGTAGAAGCTGTTATGTACATGGGCACACTTTCTTATGAACAAT TTAAGAAAGGTGTTCAGATACCTTGTACGTGTGGTAAACAAGCTACAAAATATCTAGTACAACAGGAGTC ACCTTTTGTTATGATGTCAGCACCACCTGCTCAGTATGAACTTAAGCATGGTACATTTACTTGTGCTAGT GAGTACACTGGTAATTACCAGTGTGGTCACTATAAACATATAACTTCTAAAGAAACTTTGTATTGCATAG ACGGTGCTTTACTTACAAAGTCCTCAGAATACAAAGGTCCTATTACGGATGTTTTCTACAAAGAAAACAG TTACACAACAACCATAAAACCAGTTACTTATAAATTGGATGGTGTTGTTTGTACAGAAATTGACCCTAAG TTGGACAATTATTATAAGAAAGACAATTCTTATTTCACAGAGCAACCAATTGATCTTGTACCAAACCAAC CATATCCAAACGCAAGCTTCGATAATTTTAAGTTTGTATGTGATAATATCAAATTTGCTGATGATTTAAA CCAGTTAACTGGTTATAAGAAACCTGCTTCAAGAGAGCTTAAAGTTACATTTTTCCCTGACTTAAATGGT GATGTGGTGGCTATTGATTATAAACACTACACACCCTCTTTTAAGAAAGGAGCTAAATTGTTACATAAAC CTATTGTTTGGCATGTTAACAATGCAACTAATAAAGCCACGTATAAACCAAATACCTGGTGTATACGTTG TCTTTGGAGCACAAAACCAGTTGAAACATCAAATTCGTTTGATGTACTGAAGTCAGAGGACGCGCAGGGA ATGGATAATCTTGCCTGCGAAGATCTAAAACCAGTCTCTGAAGAAGTAGTGGAAAATCCTACCATACAGA AAGACGTTCTTGAGTGTAATGTGAAAACTACCGAAGTTGTAGGAGACATTATACTTAAACCAGCAAATAA TAGTTTAAAAATTACAGAAGAGGTTGGCCACACAGATCTAATGGCTGCTTATGTAGACAATTCTAGTCTT ACTATTAAGAAACCTAATGAATTATCTAGAGTATTAGGTTTGAAAACCCTTGCTACTCATGGTTTAGCTG CTGTTAATAGTGTCCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAACAAAGTTGTTAGTAC AACTACTAACATAGTTACACGGTGTTTAAACCGTGTTTGTACTAATTATATGCCTTATTTCTTTACTTTA TTGCTACAATTGTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGCATCTATGCCGACTACTATAG CAAAGAATACTGTTAAGAGTGTCGGTAAATTTTGTCTAGAGGCTTCATTTAATTATTTGAAGTCACCTAA TTTTTCTAAACTGATAAATATTATAATTTGGTTTTTACTATTAAGTGTTTGCCTAGGTTCTTTAATCTAC TCAACCGCTGCTTTAGGTGTTTTAATGTCTAATTTAGGCATGCCTTCTTACTGTACTGGTTACAGAGAAG GCTATTTGAACTCTACTAATGTCACTATTGCAACCTACTGTACTGGTTCTATACCTTGTAGTGTTTGTCT TAGTGGTTTAGATTCTTTAGACACCTATCCTTCTTTAGAAACTATACAAATTACCATTTCATCTTTTAAA TGGGATTTAACTGCTTTTGGCTTAGTTGCAGAGTGGTTTTTGGCATATATTCTTTTCACTAGGTTTTTCT ATGTACTTGGATTGGCTGCAATCATGCAATTGTTTTTCAGCTATTTTGCAGTACATTTTATTAGTAATTC TTGGCTTATGTGGTTAATAATTAATCTTGTACAAATGGCCCCGATTTCAGCTATGGTTAGAATGTACATC TTCTTTGCATCATTTTATTATGTATGGAAAAGTTATGTGCATGTTGTAGACGGTTGTAATTCATCAACTT GTATGATGTGTTACAAACGTAATAGAGCAACAAGAGTCGAATGTACAACTATTGTTAATGGTGTTAGAAG GTCCTTTTATGTCTATGCTAATGGAGGTAAAGGCTTTTGCAAACTACACAATTGGAATTGTGTTAATTGT GATACATTCTGTGCTGGTAGTACATTTATTAGTGATGAAGTTGCGAGAGACTTGTCACTACAGTTTAAAA GACCAATAAATCCTACTGACCAGTCTTCTTACATCGTTGATAGTGTTACAGTGAAGAATGGTTCCATCCA TCTTTACTTTGATAAAGCTGGTCAAAAGACTTATGAAAGACATTCTCTCTCTCATTTTGTTAACTTAGAC AACCTGAGAGCTAATAACACTAAAGGTTCATTGCCTATTAATGTTATAGTTTTTGATGGTAAATCAAAAT GTGAAGAATCATCTGCAAAATCAGCGTCTGTTTACTACAGTCAGCTTATGTGTCAACCTATACTGTTACT AGATCAGGCATTAGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGATGCTTACGTT AATACGTTTTCATCAACTTTTAACGTACCAATGGAAAAACTCAAAACACTAGTTGCAACTGCAGAAGCTG AACTTGCAAAGAATGTGTCCTTAGACAATGTCTTATCTACTTTTATTTCAGCAGCTCGGCAAGGGTTTGT TGATTCAGATGTAGAAACTAAAGATGTTGTTGAATGTCTTAAATTGTCACATCAATCTGACATAGAAGTT ACTGGCGATAGTTGTAATAACTATATGCTCACCTATAACAAAGTTGAAAACATGACACCCCGTGACCTTG GTGCTTGTATTGACTGTAGTGCGCGTCATATTAATGCGCAGGTAGCAAAAAGTCACAACATTGCTTTGAT ATGGAACGTTAAAGATTTCATGTCATTGTCTGAACAACTACGAAAACAAATACGTAGTGCTGCTAAAAAG AATAACTTACCTTTTAAGTTGACATGTGCAACTACTAGACAAGTTGTTAATGTTGTAACAACAAAGATAG CACTTAAGGGTGGTAAAATTGTTAATAATTGGTTGAAGCAGTTAATTAAAGTTACACTTGTGTTCCTTTT TGTTGCTGCTATTTTCTATTTAATAACACCTGTTCATGTCATGTCTAAACATACTGACTTTTCAAGTGAA ATCATAGGATACAAGGCTATTGATGGTGGTGTCACTCGTGACATAGCATCTACAGATACTTGTTTTGCTA ACAAACATGCTGATTTTGACACATGGTTTAGCCAGCGTGGTGGTAGTTATACTAATGACAAAGCTTGCCC ATTGATTGCTGCAGTCATAACAAGAGAAGTGGGTTTTGTCGTGCCTGGTTTGCCTGGCACGATATTACGC ACAACTAATGGTGACTTTTTGCATTTCTTACCTAGAGTTTTTAGTGCAGTTGGTAACATCTGTTACACAC CATCAAAACTTATAGAGTACACTGACTTTGCAACATCAGCTTGTGTTTTGGCTGCTGAATGTACAATTTT TAAAGATGCTTCTGGTAAGCCAGTACCATATTGTTATGATACCAATGTACTAGAAGGTTCTGTTGCTTAT GAAAGTTTACGCCCTGACACACGTTATGTGCTCATGGATGGCTCTATTATTCAATTTCCTAACACCTACC TTGAAGGTTCTGTTAGAGTGGTAACAACTTTTGATTCTGAGTACTGTAGGCACGGCACTTGTGAAAGATC AGAAGCTGGTGTTTGTGTATCTACTAGTGGTAGATGGGTACTTAACAATGATTATTACAGATCTTTACCA GGAGTTTTCTGTGGTGTAGATGCTGTAAATTTACTTACTAATATGTTTACACCACTAATTCAACCTATTG GTGCTTTGGACATATCAGCATCTATAGTAGCTGGTGGTATTGTAGCTATCGTAGTAACATGCCTTGCCTA CTATTTTATGAGGTTTAGAAGAGCTTTTGGTGAATACAGTCATGTAGTTGCCTTTAATACTTTACTATTC CTTATGTCATTCACTGTACTCTGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTGTTATTT ACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTTTTTAGCACATATTCAGTGGATGGTTATGTT CACACCTTTAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAGCATTTCTATTGG TTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATGGTGTTTCCTTTAGTACTTTTGAAGAAGCTG CGCTGTGCACCTTTTTGTTAAATAAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTATTACCTCTTAC GCAATATAATAGATACTTAGCTCTTTATAATAAGTACAAGTATTTTAGTGGAGCAATGGATACAACTAGC TACAGAGAAGCTGCTTGTTGTCATCTCGCAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTC TTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCC ATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTT GATGACGTAGTTTACTGTCCAAGACATGTGATCTGCACCTCTGAAGACATGCTTAACCCTAATTATGAAG ATTTACTCATTCGTAAGTCTAATCATAATTTCTTGGTACAGGCTGGTAATGTTCAACTCAGGGTTATTGG ACATTCTATGCAAAATTGTGTACTTAAGCTTAAGGTTGATACAGCCAATCCTAAGACACCTAAGTATAAG TTTGTTCGCATTCAACCAGGACAGACTTTTTCAGTGTTAGCTTGTTACAATGGTTCACCATCTGGTGTTT ACCAATGTGCTATGAGGCCCAATTTCACTATTAAGGGTTCATTCCTTAATGGTTCATGTGGTAGTGTTGG TTTTAACATAGATTATGACTGTGTCTCTTTTTGTTACATGCACCATATGGAATTACCAACTGGAGTTCAT GCTGGCACAGACTTAGAAGGTAACTTTTATGGACCTTTTGTTGACAGGCAAACAGCACAAGCAGCTGGTA CGGACACAACTATTACAGTTAATGTTTTAGCTTGGTTGTACGCTGCTGTTATAAATGGAGACAGGTGGTT TCTCAATCGATTTACCACAACTCTTAATGACTTTAACCTTGTGGCTATGAAGTACAATTATGAACCTCTA ACACAAGACCATGTTGACATACTAGGACCTCTTTCTGCTCAAACTGGAATTGCCGTTTTAGATATGTGTG CTTCATTAAAAGAATTACTGCAAAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTATTAGAAGA TGAATTTACACCTTTTGATGTTGTTAGACAATGCTCAGGTGTTACTTTCCAAAGTGCAGTGAAAAGAACA ATCAAGGGTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTTAGTCCAGAGTACTC AATGGTCTTTGTTCTTTTTTTTGTATGAAAATGCCTTTTTACCTTTTGCTATGGGTATTATTGCTATGTC TGCTTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTTGTTTTTGTTACCTTCTCTTGCC ACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATA TGGTTGATACTAGTTTGTCTGGTTTTAAGCTAAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACT AATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACACTTATGAATGTCTTG ACACTCGTTTATAAAGTTTATTATGGTAATGCTTTAGATCAAGCCATTTCCATGTGGGCTCTTATAATCT CTGTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCATGTTTTTGGCCAGAGGTATTGTTTTTATGTG TGTTGAGTATTGCCCTATTTTCTTCATAACTGGTAATACACTTCAGTGTATAATGCTAGTTTATTGTTTC TTAGGCTATTTTTGTACTTGTTACTTTGGCCTCTTTTGTTTACTCAACCGCTACTTTAGACTGACTCTTG GTGTTTATGATTACTTAGTTTCTACACAGGAGTTTAGATATATGAATTCACAGGGACTACTCCCACCCAA GAATAGCATAGATGCCTTCAAACTCAACATTAAATTGTTGGGTGTTGGTGGCAAACCTTGTATCAAAGTA GCCACTGTACAGTCTAAAATGTCAGATGTAAAGTGCACATCAGTAGTCTTACTCTCAGTTTTGCAACAAC TCAGAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGTCCAGTTACACAATGACATTCTCTTAGCTAA AGATACTACTGAAGCCTTTGAAAAAATGGTTTCACTACTTTCTGTTTTGCTTTCCATGCAGGGTGCTGTA GACATAAACAAGCTTTGTGAAGAAATGCTGGACAACAGGGCAACCTTACAAGCTATAGCCTCAGAGTTTA GTTCCCTTCCATCATATGCAGCTTTTGCTACTGCTCAAGAAGCTTATGAGCAGGCTGTTGCTAATGGTGA TTCTGAAGTTGTTCTTAAAAAGTTGAAGAAGTCTTTGAATGTGGCTAAATCTGAATTTGACCGTGATGCA GCCATGCAACGTAAGTTGGAAAAGATGGCTGATCAAGCTATGACCCAAATGTATAAACAGGCTAGATCTG AGGACAAGAGGGCAAAAGTTACTAGTGCTATGCAGACAATGCTTTTCACTATGCTTAGAAAGTTGGATAA TGATGCACTCAACAACATTATCAACAATGCAAGAGATGGTTGTGTTCCCTTGAACATAATACCTCTTACA ACAGCAGCCAAACTAATGGTTGTCATACCAGACTATAACACATATAAAAATACGTGTGATGGTACAACAT TTACTTATGCATCAGCATTGTGGGAAATCCAACAGGTTGTAGATGCAGATAGTAAAATTGTTCAACTTAG TGAAATTAGTATGGACAATTCACCTAATTTAGCATGGCCTCTTATTGTAACAGCTTTAAGGGCCAATTCT GCTGTCAAATTACAGAATAATGAGCTTAGTCCTGTTGCACTACGACAGATGTCTTGTGCTGCCGGTACTA CACAAACTGCTTGCACTGATGACAATGCGTTAGCTTACTACAACACAACAAAGGGAGGTAGGTTTGTACT TGCACTGTTATCCGATTTACAGGATTTGAAATGGGCTAGATTCCCTAAGAGTGATGGAACTGGTACTATC TATACAGAACTGGAACCACCTTGTAGGTTTGTTACAGACACACCTAAAGGTCCTAAAGTGAAGTATTTAT ACTTTATTAAAGGATTAAACAACCTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCCACAGTACGTCT ACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGAT GCTGCTAAAGCTTACAAAGATTATCTAGCTAGTGGGGGACAACCAATCACTAATTGTGTTAAGATGTTGT GTACACACACTGGTACTGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAATCCTTTGG TGGTGCATCGTGTTGTCTGTACTGCCGTTGCCACATAGATCATCCAAATCCTAAAGGATTTTGTGACTTA AAAGGTAAGTATGTACAAATACCTACAACTTGTGCTAATGACCCTGTGGGTTTTACACTTAAAAACACAG TCTGTACCGTCTGCGGTATGTGGAAAGGTTATGGCTGTAGTTGTGATCAACTCCGCGAACCCATGCTTCA GTCAGCTGATGCACAATCGTTTTTAAACGGGTTTGCGGTGTAAGTGCAGCCCGTCTTACACCGTGCGGCA CAGGCACTAGTACTGATGTCGTATACAGGGCTTTTGACATCTACAATGATAAAGTAGCTGGTTTTGCTAA ATTCCTAAAAACTAATTGTTGTCGCTTCCAAGAAAAGGACGAAGATGACAATTTAATTGATTCTTACTTT GTAGTTAAGAGACACACTTTCTCTAACTACCAACATGAAGAAACAATTTATAATTTACTTAAGGATTGTC CAGCTGTTGCTAAACATGACTTCTTTAAGTTTAGAATAGACGGTGACATGGTACCACATATATCACGTCA ACGTCTTACTAAATACACAATGGCAGACCTCGTCTATGCTTTAAGGCATTTTGATGAAGGTAATTGTGAC ACATTAAAAGAAATACTTGTCACATACAATTGTTGTGATGATGATTATTTCAATAAAAAGGACTGGTATG ATTTTGTAGAAAACCCAGATATATTACGCGTATACGCCAACTTAGGTGAACGTGTACGCCAAGCTTTGTT AAAAACAGTACAATTCTGTGATGCCATGCGAAATGCTGGTATTGTTGGTGTACTGACATTAGATAATCAA GATCTCAATGGTAACTGGTATGATTTCGGTGATTTCATACAAACCACGCCAGGTAGTGGAGTTCCTGTTG TAGATTCTTATTATTCATTGTTAATGCCTATATTAACCTTGACCAGGGCTTTAACTGCAGAGTCACATGT TGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGAGGTTA AAACTCTTTGACCGTTATTTTAAATATTGGGATCAGACATACCACCCAAATTGTGTTAACTGTTTGGATG ACAGATGCATTCTGCATTGTGCAAACTTTAATGTTTTATTCTCTACAGTGTTCCCACCTACAAGTTTTGG ACCACTAGTGAGAAAAATATTTGTTGATGGTGTTCCATTTGTAGTTTCAACTGGATACCACTTCAGAGAG CTAGGTGTTGTACATAATCAGGATGTAAACTTACATAGCTCTAGACTTAGTTTTAAGGAATTACTTGTGT ATGCTGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTATTACTAGATAAACGCACTACGTGCTTTTC AGTAGCTGCACTTACTAACAATGTTGCTTTTCAAACTGTCAAACCCGGTAATTTTAACAAAGACTTCTAT GACTTTGCTGTGTCTAAGGGTTTCTTTAAGGAAGGAAGTTCTGTTGAATTAAAACACTTCTTCTTTGCTC AGGATGGTAATGCTGCTATCAGCGATTATGACTACTATCGTTATAATCTACCAACAATGTGTGATATCAG ACAACTACTATTTGTAGTTGAAGTTGTTGATAAGTACTTTGATTGTTACGATGGTGGCTGTATTAATGCT AACCAAGTCATCGTCAACAACCTAGACAAATCAGCTGGTTTTCCATTTAATAAATGGGGTAAGGCTAGAC TTTATTATGATTCAATGAGTTATGAGGATCAAGATGCACTTTTCGCATATACAAAACGTAATGTCATCCC TACTATAACTCAAATGAATCTTAAGTATGCCATTAGTGCAAAGAATAGAGCTCGCACCGTAGCTGGTGTC TCTATCTGTAGTACTATGACCAATAGACAGTTTCATCAAAAATTATTGAAATCAATAGCCGCCACTAGAG GAGCTACTGTAGTAATTGGAACAAGCAAATTCTATGGTGGTTGGCACAACATGTTAAAAACTGTTTATAG TGATGTAGAAAACCCTCACCTTATGGGTTGGGATTATCCTAAATGTGATAGAGCCATGCCTAACATGCTT AGAATTATGGCCTCACTTGTTCTTGCTCGCAAACATACAACGTGTTGTAGCTTGTCACACCGTTTCTATA GATTAGCTAATGAGTGTGCTCAAGTATTGAGTGAAATGGTCATGTGTGGCGGTTCACTATATGTTAAACC AGGTGGAACCTCATCAGGAGATGCCACAACTGCTTATGCTAATAGTGTTTTTAACATTTGTCAAGCTGTC ACGGCCAATGTTAATGCACTTTTATCTACTGATGGTAACAAAATTGCCGATAAGTATGTCCGCAATTTAC AACACAGACTTTATGAGTGTCTCTATAGAAATAGAGATGTTGACACAGACTTTGTGAATGAGTTTTACGC ATATTTGCGTAAACATTTCTCAATGATGATACTCTCTGACGATGCTGTTGTGTGTTTCAATAGCACTTAT GCATCTCAAGGTCTAGTGGCTAGCATAAAGAACTTTAAGTCAGTTCTTTATTATCAAAACAATGTTTTTA TGTCTGAAGCAAAATGTTGGACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCAACATAC AATGCTAGTTAAACAGGGTGATGATTATGTGTACCTTCCTTACCCAGATCCATCAAGAATCCTAGGGGCC GGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATTGAACGGTTCGTGTCTTTAGCTA TAGATGCTTACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTCATTTGTACTTACAATA CATAAGAAAGCTACATGATGAGTTAACAGGACACATGTTAGACATGTATTCTGTTATGCTTACTAATGAT AACACTTCAAGGTATTGGGAACCTGAGTTTTATGAGGCTATGTACACACCGCATACAGTCTTACAGGCTG TTGGGGCTTGTGTTCTTTGCAATTCACAGACTTCATTAAGATGTGGTGCTTGCATACGTAGACCATTCTT ATGTTGTAAATGCTGTTACGACCATGTCATATCAACATCACATAAATTAGTCTTGTCTGTTAATCCGTAT GTTTGCAATGCTCCAGGTTGTGATGTCACAGATGTGACTCAACTTTACTTAGGAGGTATGAGCTATTATT GTAAATCACATAAACCACCCATTAGTTTTCCATTGTGTGCTAATGGACAAGTTTTTGGTTTATATAAAAA TACATGTGTTGGTAGCGATAATGTTACTGACTTTAATGCAATTGCAACATGTGACTGGACAAATGCTGGT GATTACATTTTAGCTAACACCTGTACTGAAAGACTCAAGCTTTTTGCAGCAGAAACGCTCAAAGCTACTG AGGAGACATTTAAACTGTCTTATGGTATTGCTACTGTACGTGAAGTGCTGTCTGACAGAGAATTACATCT TTCATGGGAAGTTGGTAAACCTAGACCACCACTTAACCGAAATTATGTCTTTACTGGTTATCGTGTAACT AAAAACAGTAAAGTACAAATAGGAGAGTACACCTTTGAAAAAGGTGACTATGGTGATGCTGTTGTTTACC GAGGTACAACAACTTACAAATTAAATGTTGGTGATTATTTTGTGCTGACATCACATACAGTAATGCCATT AAGTGCACCTACACTAGTGCCACAAGAGCACTATGTTAGAATTACTGGCTTATACCCAACACTCAATATC TCAGATGAGTTTTCTAGCAATGTTGCAAATTATCAAAAGGTTGGTATGCAAAAGTATTCTACACTCCAGG GACCACCTGGTACTGGTAAGAGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGT GTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAGGCATTAAAATATTTGCCTATAGAT AAATGTAGTAGAATTATACCTGCACGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTGAATTCAACAT TAGAACAGTATGTCTTTTGTACTGTAAATGCATTGCCTGAGACGACAGCAGATATAGTTGTCTTTGATGA AATTTCAATGGCCACAAATTATGATTTGAGTGTTGTCAATGCCAGATTACGTGCTAAGCACTATGTGTAC ATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTGCTAACTAAGGGCACACTAGAACCAGAATATT TCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCCAGACATGTTCCTCGGAACTTGTCGGCGTTGTCC TGCTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCTTAAAGCACATAAAGACAAATCA GCTCAATGCTTTAAAATGTTTTATAAGGGTGTTATCACGCATGATGTTTCATCTGCAATTAACAGGCCAC AAATAGGCGTGGTAAGAGAATTCCTTACACGTAACCCTGCTTGGAGAAAAGCTGTCTTTATTTCACCTTA TAATTCACAGAATGCTGTAGCCTCAAAGATTTTGGGACTACCAACTCAAACTGTTGATTCATCACAGGGC TCAGAATATGACTATGTCATATTCACTCAAACCACTGAAACAGCTCACTCTTGTAATGTAAACAGATTTA ATGTTGCTATTACCAGAGCAAAAGTAGGCATACTTTGCATAATGTCTGATAGAGACCTTTATGACAAGTT GCAATTTACAAGTCTTGAAATTCCACGTAGGAATGTGGCAACTTTACAAGCTGAAAATGTAACAGGACTC TTTAAAGATTGTAGTAAGGTAATCACTGGGTTACATCCTACACAGGCACCTACACACCTCAGTGTTGACA CTAAATTCAAAACTGAAGGTTTATGTGTTGACATACCTGGCATACCTAAGGACATGACCTATAGAAGACT CATCTCTATGATGGGTTTTAAAATGAATTATCAAGTTAATGGTTACCCTAACATGTTTATCACCCGCGAA GAAGCTATAAGACATGTACGTGCATGGATTGGCTTCGATGTCGAGGGGTGTCATGCTACTAGAGAAGCTG TTGGTACCAATTTACCTTTACAGCTAGGTTTTTCTACAGGTGTTAACCTAGTTGCTGTACCTACAGGTTA TGTTGATACACCTAATAATACAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAA CACCTCATACCACTTATGTACAAAGGACTTCCTTGGAATGTAGTGCGTATAAAGATTGTACAAATGTTAA GTGACACACTTAAAAATCTCTCTGACAGAGTCGTATTTGTCTTATGGGCACATGGCTTTGAGTTGACATC TATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGACGTGCCACATGCTTT TCCACTGCTTCAGACACTTATGCCTGTTGGCATCATTCTATTGGATTTGATTACGTCTATAATCCGTTTA TGATTGATGTTCAACAATGGGGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCA TGGTAATGCACATGTAGCTAGTTGTGATGCAATCATGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTT AAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAA AGGTTCAACACATGGTTGTTAAAGCTGCATTATTAGCAGACAAATTCCCAGTTCTTCACGACATTGGTAA CCCTAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAATGGAAGTTCTATGATGCACAGCCTTGTAGT GACAAAGCTTATAAAATAGAAGAATTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTG TATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAG AGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTTGTATGTAAATAAACATGCATTCCAC ACACCAGCTTTTGATAAAAGTGCTTTTGTTAATTTAAAACAATTACCATTTTTCTATTACTCTGACAGTC CATGTGAGTCTCATGGAAAACAAGTAGTGTCAGATATAGATTATGTACCACTAAAGTCTGCTACGTGTAT AACACGTTGCAATTTAGGTGGTGCTGTCTGTAGACATCATGCTAATGAGTACAGATTGTATCTCGATGCT TATAACATGATGATCTCAGCTGGCTTTAGCTTGTGGGTTTACAAACAATTTGATACTTATAACCTCTGGA ACACTTTTACAAGACTTCAGAGTTTAGAAAATGTGGCTTTTAATGTTGTAAATAAGGGACACTTTGATGG ACAACAGGGTGAAGTACCAGTTTCTATCATTAATAACACTGTTTACACAAAAGTTGATGGTGTTGATGTA GAATTGTTTGAAAATAAAACAACATTACCTGTTAATGTAGCATTTGAGCTTTGGGCTAAGCGCAACATTA AACCAGTACCAGAGGTGAAAATACTCAATAATTTGGGTGTGGACATTGCTGCTAATACTGTGATCTGGGA CTACAAAAGAGATGCTCCAGCACATATATCTACTATTGGTGTTTGTTCTATGACTGACATAGCCAAGAAA CCAACTGAAACGATTTGTGCACCACTCACTGTCTTTTTTGATGGTAGAGTTGATGGTCAAGTAGACTTAT TTAGAAATGCCCGTAATGGTGTTCTTATTACAGAAGGTAGTGTTAAAGGTTTACAACCATCTGTAGGTCC CAAACAAGCTAGTCTTAATGGAGTCACATTAATTGGAGAAGCCGTAAAAACACAGTTCAATTATTATAAG AAAGTTGATGGTGTTGTCCAACAATTACCTGAAACTTACTTTACTCAGAGTAGAAATTTACAAGAATTTA AACCCAGGAGTCAAATGGAAATTGATTTCTTAGAATTAGCTATGGATGAATTCATTGAACGGTATAAATT AGAAGGCTATGCCTTCGAACATATCGTTTATGGAGATTTTAGTCATAGTCAGTTAGGTGGTTTACATCTA CTGATTGGACTAGCTAAACGTTTTAAGGAATCACCTTTTGAATTAGAAGATTTTATTCCTATGGACAGTA CAGTTAAAAACTATTTCATAACAGATGCGCAAACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTT ATTACTTGATGATTTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTG ACTATTGACTATACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACATTTTACCCAA AATTACAATCTAGTCAAGCGTGGCAACCGGGTGTTGCTATGCCTAATCTTTACAAAATGCAAAGAATGCT ATTAGAAAAGTGTGACCTTCAAAATTATGGTGATAGTGCAACATTACCTAAAGGCATAATGATGAATGTC GCAAAATATACTCAACTGTGTCAATATTTAAACACATTAACATTAGCTGTACCCTATAATATGAGAGTTA TACATTTTGGTGCTGGTTCTGATAAAGGAGTTGCACCAGGTACAGCTGTTTTAAGACAGTGGTTGCCTAC GGGTACGCTGCTTGTCGATTCAGATCTTAATGACTTTGTCTCTGATGCAGATTCAACTTTGATTGGTGAT TGTGCAACTGTACATACAGCTAATAAATGGGATCTCATTATTAGTGATATGTACGACCCTAAGACTAAAA ATGTTACAAAAGAAAATGACTCTAAAGAGGGTTTTTTCACTTACATTTGTGGGTTTATACAACAAAAGCT AGCTCTTGGAGGTTCCGTGGCTATAAAGATAACAGAACATTCTTGGAATGCTGATCTTTATAAGCTCATG GGACACTTCGCATGGTGGACAGCCTTTGTTACTAATGTGAATGCGTCATCATCTGAAGCATTTTTAATTG GATGTAATTATCTTGGCAAACCACGCGAACAAATAGATGGTTATGTCATGCATGCAAATTACATATTTTG GAGGAATACAAATCCAATTCAGTTGTCTTCCTATTCTTTATTTGACATGAGTAAATTTCCCCTTAAATTA AGGGGTACTGCTGTTATGTCTTTAAAAGAAGGTCAAATCAATGATATGATTTTATCTCTTCTTAGTAAAG GTAGACTTATAATTAGAGAAAACAACAGAGTTGTTATTTCTAGTGATGTTCTTGTTAACAACTAAACGAA CAATGTTTGTTTTTCTTGTTTTATTGCCACTAGTCTCTAGTCAGTGTGTTAATCTTACAACCAGAACTCA ATTACCCCCTGCATACACTAATTCTTTCACACGTGGTGTTTATTACCCTGACAAAGTTTTCAGATCCTCA GTTTTACATTCAACTCAGGACTTGTTCTTACCTTTCTTTTCCAATGTTACTTGGTTCCATGCTATACATG TCTCTGGGACCAATGGTACTAAGAGGTTTGATAACCCTGTCCTACCATTTAATGATGGTGTTTATTTTGC TTCCACTGAGAAGTCTAACATAATAAGAGGCTGGATTTTTGGTACTACTTTAGATTCGAAGACCCAGTCC CTACTTATTGTTAATAACGCTACTAATGTTGTTATTAAAGTCTGTGAATTTCAATTTTGTAATGATCCAT TTTTGGGTGTTTATTACCACAAAAACAACAAAAGTTGGATGGAAAGTGAGTTCAGAGTTTATTCTAGTGC GAATAATTGCACTTTTGAATATGTCTCTCAGCCTTTTCTTATGGACCTTGAAGGAAAACAGGGTAATTTC AAAAATCTTAGGGAATTTGTGTTTAAGAATATTGATGGTTATTTTAAAATATATTCTAAGCACACGCCTA TTAATTTAGTGCGTGATCTCCCTCAGGGTTTTTCGGCTTTAGAACCATTGGTAGATTTGCCAATAGGTAT TAACATCACTAGGTTTCAAACTTTACTTGCTTTACATAGAAGTTATTTGACTCCTGGTGATTCTTCTTCA GGTTGGACAGCTGGTGCTGCAGCTTATTATGTGGGTTATCTTCAACCTAGGACTTTTCTATTAAAATATA ATGAAAATGGAACCATTACAGATGCTGTAGACTGTGCACTTGACCCTCTCTCAGAAACAAAGTGTACGTT GAAATCCTTCACTGTAGAAAAAGGAATCTATCAAACTTCTAACTTTAGAGTCCAACCAACAGAATCTATT GTTAGATTTCCTAATATTACAAACTTGTGCCCTTTTGGTGAAGTTTTTAACGCCACCAGATTTGCATCTG TTTATGCTTGGAACAGGAAGAGAATCAGCAACTGTGTTGCTGATTATTCTGTCCTATATAATTCCGCATC ATTTTCCACTTTTAAGTGTTATGGAGTGTCTCCTACTAAATTAAATGATCTCTGCTTTACTAATGTCTAT GCAGATTCATTTGTAATTAGAGGTGATGAAGTCAGACAAATCGCTCCAGGGCAAACTGGAAAGATTGCTG ATTATAATTATAAATTACCAGATGATTTTACAGGCTGCGTTATAGCTTGGAATTCTAACAATCTTGATTC TAAGGTTGGTGGTAATTATAATTACCTGTATAGATTGTTTAGGAAGTCTAATCTCAAACCTTTTGAGAGA GATATTTCAACTGAAATCTATCAGGCCGGTAGCACACCTTGTAATGGTGTTGAAGGTTTTAATTGTTACT TTCCTTTACAATCATATGGTTTCCAACCCACTAATGGTGTTGGTTACCAACCATACAGAGTAGTAGTACT TTCTTTTGAACTTCTACATGCACCAGCAACTGTTTGTGGACCTAAAAAGTCTACTAATTTGGTTAAAAAC AAATGTGTCAATTTCAACTTCAATGGTTTAACAGGCACAGGTGTTCTTACTGAGTCTAACAAAAAGTTTC TGCCTTTCCAACAATTTGGCAGAGACATTGCTGACACTACTGATGCTGTCCGTGATCCACAGACACTTGA GATTCTTGACATTACACCATGTTCTTTTGGTGGTGTCAGTGTTATAACACCAGGAACAAATACTTCTAAC CAGGTTGCTGTTCTTTATCAGGATGTTAACTGCACAGAAGTCCCTGTTGCTATTCATGCAGATCAACTTA CTCCTACTTGGCGTGTTTATTCTACAGGTTCTAATGTTTTTCAAACACGTGCAGGCTGTTTAATAGGGGC TGAACATGTCAACAACTCATATGAGTGTGACATACCCATTGGTGCAGGTATATGCGCTAGTTATCAGACT CAGACTAATTCTCCTCGGCGGGCACGTAGTGTAGCTAGTCAATCCATCATTGCCTACACTATGTCACTTG GTGCAGAAAATTCAGTTGCTTACTCTAATAACTCTATTGCCATACCCACAAATTTTACTATTAGTGTTAC CACAGAAATTCTACCAGTGTCTATGACCAAGACATCAGTAGATTGTACAATGTACATTTGTGGTGATTCA ACTGAATGCAGCAATCTTTTGTTGCAATATGGCAGTTTTTGTACACAATTAAACCGTGCTTTAACTGGAA TAGCTGTTGAACAAGACAAAAACACCCAAGAAGTTTTTGCACAAGTCAAACAAATTTACAAAACACCACC AATTAAAGATTTTGGTGGTTTTAATTTTTCACAAATATTACCAGATCCATCAAAACCAAGCAAGAGGTCA TTTATTGAAGATCTACTTTTCAACAAAGTGACACTTGCAGATGCTGGCTTCATCAAACAATATGGTGATT GCCTTGGTGATATTGCTGCTAGAGACCTCATTTGTGCACAAAAGTTTAACGGCCTTACTGTTTTGCCACC TTTGCTCACAGATGAAATGATTGCTCAATACACTTCTGCACTGTTAGCGGGTACAATCACTTCTGGTTGG ACCTTTGGTGCAGGTGCTGCATTACAAATACCATTTGCTATGCAAATGGCTTATAGGTTTAATGGTATTG GAGTTACACAGAATGTTCTCTATGAGAACCAAAAATTGATTGCCAACCAATTTAATAGTGCTATTGGCAA AATTCAAGACTCACTTTCTTCCACAGCAAGTGCACTTGGAAAACTTCAAGATGTGGTCAACCAAAATGCA CAAGCTTTAAACACGCTTGTTAAACAACTTAGCTCCAATTTTGGTGCAATTTCAAGTGTTTTAAATGATA TCCTTTCACGTCTTGACAAAGTTGAGGCTGAAGTGCAAATTGATAGGTTGATCACAGGCAGACTTCAAAG TTTGCAGACATATGTGACTCAACAATTAATTAGAGCTGCAGAAATCAGAGCTTCTGCTAATCTTGCTGCT ACTAAAATGTCAGAGTGTGTACTTGGACAATCAAAAAGAGTTGATTTTTGTGGAAAGGGCTATCATCTTA TGTCCTTCCCTCAGTCAGCACCTCATGGTGTAGTCTTCTTGCATGTGACTTATGTCCCTGCACAAGAAAA GAACTTCACAACTGCTCCTGCCATTTGTCATGATGGAAAAGCACACTTTCCTCGTGAAGGTGTCTTTGTT TCAAATGGCACACACTGGTTTGTAACACAAAGGAATTTTTATGAACCACAAATCATTACTACAGACAACA CATTTGTGTCTGGTAACTGTGATGTTGTAATAGGAATTGTCAACAACACAGTTTATGATCCTTTGCAACC TGAATTAGACTCATTCAAGGAGGAGTTAGATAAATATTTTAAGAATCATACATCACCAGATGTTGATTTA GGTGACATCTCTGGCATTAATGCTTCAGTTGTAAACATTCAAAAAGAAATTGACCGCCTCAATGAGGTTG CCAAGAATTTAAATGAATCTCTCATCGATCTCCAAGAACTTGGAAAGTATGAGCAGTATATAAAATGGCC ATGGTACATTTGGCTAGGTTTTATAGCTGGCTTGATTGCCATAGTAATGGTGACAATTATGCTTTGCTGT ATGACCAGTTGCTGTAGTTGTCTCAAGGGCTGTTGTTCTTGTGGATCCTGCTGCAAATTTGATGAAGACG ACTCTGAGCCAGTGCTCAAAGGAGTCAAATTACATTACACATAAACGAACTTATGGATTTGTTTATGAGA ATCTTCACAATTGGAACTGTAACTTTGAAGCAAGGTGAAATCAAGGATGCTACTCCTTCAGATTTTGTTC GCGCTACTGCAACGATACCGATACAAGCCTCACTCCCTTTCGGATGGCTTATTGTTGGCGTTGCACTTCT TGCTGTTTTTCAGAGCGCTTCCAAAATCATAACCCTCAAAAAGAGATGGCAACTAGCACTCTCCAAGGGT GTTCACTTTGTTTGCAACTTGCTGTTGTTGTTTGTAACAGTTTACTCACACCTTTTGCTCGTTGCTGCTG GCCTTGAAGCCCCTTTTCTCTATCTTTATGCTTTAGTCTACTTCTTGCAGAGTATAAACTTTGTAAGAAT AATAATGAGGCTTTGGCTTTGCTGGAAATGCCGTTCCAAAAACCCATTACTTTATGATGCCAACTATTTT CTTTGCTGGCATACTAATTGTTACGACTATTGTATACCTTACAATAGTGTAACTTCTTCAATTGTCATTA CTTCAGGTGATGGCACAACAAGTCCTATTTCTGAACATGACTACCAGATTGGTGGTTATACTGAAAAATG GGAATCTGGAGTAAAAGACTGTGTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCA ACTCAATTGAGTACAGACACTGGTGTTGAACATGTTACCTTCTTCATCTACAATAAAATTGTTGATGAGC CTGAAGAACATGTCCAAATTCACACAATCGACGGTTCATCCGGAGTTGTTAATCCAGTAATGGAACCAAT TTATGATGAACCGACGACGACTACTAGCGTGCCTTTGTAAGCACAAGCTGATGAGTACGAACTTATGTAC TCATTCGTTTCGGAAGAGACAGGTACGTTAATAGTTAATAGCGTACTTCTTTTTCTTGCTTTCGTGGTAT TCTTGCTAGTTACACTAGCCATCCTTACTGCGCTTCGATTGTGTGCGTACTGCTGCAATATTGTTAACGT GAGTCTTGTAAAACCTTCTTTTTACGTTTACTCTCGTGTTAAAAATCTGAATTCTTCTAGAGTTCCTGAT CTTCTGGTCTAAACGAACTAAATATTATATTAGTTTTTCTGTTTGGAACTTTAATTTTAGCCATGGCAGA TTCCAACGGTACTATTACCGTTGAAGAGCTTAAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTC CTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTATGCCAACAGGAATAGGTTTTTGTATATAATTA AGTTAATTTTCCTCTGGCTGTTATGGCCAGTAACTTTAGCTTGTTTTGTGCTTGCTGCTGTTTACAGAAT AAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTC ATTGCTTCTTTCAGACTGTTTGCGCGTACGCGTTCCATGTGGTCATTCAATCCAGAAACTAACATTCTTC TCAACGTGCCACTCCATGGCACTATTCTGACCAGACCGCTTCTAGAAAGTGAACTCGTAATCGGAGCTGT GATCCTTCGTGGACATCTTCGTATTGCTGGACACCATCTAGGACGCTGTGACATCAAGGACCTGCCTAAA GAAATCACTGTTGCTACATCACGAACGCTTTCTTATTACAAATTGGGAGCTTCGCAGCGTGTAGCAGGTG ACTCAGGTTTTGCTGCATACAGTCGCTACAGGATTGGCAACTATAAATTAAACACAGACCATTCCAGTAG CAGTGACAATATTGCTTTGCTTGTACAGTAAGTGACAACAGATGTTTCATCTCGTTGACTTTCAGGTTAC TATAGCAGAGATATTACTAATTATTATGAGGACTTTTAAAGTTTCCATTTGGAATCTTGATTACATCATA AACCTCATAATTAAAAATTTATCTAAGTCACTAACTGAGAATAAATATTCTCAATTAGATGAAGAGCAAC CAATGGAGATTGATTAAACGAACATGAAAATTATTCTTTTCTTGGCACTGATAACACTCGCTACTTGTGA GCTTTATCACTACCAAGAGTGTGTTAGAGGTACAACAGTACTTTTAAAAGAACCTTGCTCTTCTGGAACA TACGAGGGCAATTCACCATTTCATCCTCTAGCTGATAACAAATTTGCACTGACTTGCTTTAGCACTCAAT TTGCTTTTGCTTGTCCTGACGGCGTAAAACACGTCTATCAGTTACGTGCCAGATCAGTTTCACCTAAACT GTTCATCAGACAAGAGGAAGTTCAAGAACTTTACTCTCCAATTTTTCTTATTGTTGCGGCAATAGTGTTT ATAACACTTTGCTTCACACTCAAAAGAAAGACAGAATGATTGAACTTTCATTAATTGACTTCTATTTGTG CTTTTTAGCCTTTCTGCTATTCCTTGTTTTAATTATGCTTATTATCTTTTGGTTCTCACTTGAACTGCAA GATCATAATGAAACTTGTCACGCCTAAACGAACATGAAATTTCTTGTTTTCTTAGGAATCATCACAACTG TAGCTGCATTTCACCAAGAATGTAGTTTACAGTCATGTACTCAACATCAACCATATGTAGTTGATGACCC GTGTCCTATTCACTTCTATTCTAAATGGTATATTAGAGTAGGAGCTAGAAAATCAGCACCTTTAATTGAA TTGTGCGTGGATGAGGCTGGTTCTAAATCACCCATTCAGTACATCGATATCGGTAATTATACAGTTTCCT GTTTACCTTTTACAATTAATTGCCAGGAACCTAAATTGGGTAGTCTTGTAGTGCGTTGTTCGTTCTATGA AGACTTTTTAGAGTATCATGACGTTCGTGTTGTTTTAGATTTCATCTAAACGAACAAACTAAAATGTCTG ATAATGGACCCCAAAATCAGCGAAATGCACCCCGCATTACGTTTGGTGGACCCTCAGATTCAACTGGCAG TAACCAGAATGGAGAACGCAGTGGGGCGCGATCAAAACAACGTCGGCCCCAAGGTTTACCCAATAATACT GCGTCTTGGTTCACCGCTCTCACTCAACATGGCAAGGAAGACCTTAAATTCCCTCGAGGACAAGGCGTTC CAATTAACACCAATAGCAGTCCAGATGACCAAATTGGCTACTACCGAAGAGCTACCAGACGAATTCGTGG TGGTGACGGTAAAATGAAAGATCTCAGTCCAAGATGGTATTTCTACTACCTAGGAACTGGGCCAGAAGCT GGACTTCCCTATGGTGCTAACAAAGACGGCATCATATGGGTTGCAACTGAGGGAGCCTTGAATACACCAA AAGATCACATTGGCACCCGCAATCCTGCTAACAATGCTGCAATCGTGCTACAACTTCCTCAAGGAACAAC ATTGCCAAAAGGCTTCTACGCAGAAGGGAGCAGAGGCGGCAGTCAAGCCTCTTCTCGTTCCTCATCACGT AGTCGCAACAGTTCAAGAAATTCAACTCCAGGCAGCAGTAGGGGAACTTCTCCTGCTAGAATGGCTGGCA ATGGCGGTGATGCTGCTCTTGCTTTGCTGCTGCTTGACAGATTGAACCAGCTTGAGAGCAAAATGTCTGG TAAAGGCCAACAACAACAAGGCCAAACTGTCACTAAGAAATCTGCTGCTGAGGCTTCTAAGAAGCCTCGG CAAAAACGTACTGCCACTAAAGCATACAATGTAACACAAGCTTTCGGCAGACGTGGTCCAGAACAAACCC AAGGAAATTTTGGGGACCAGGAACTAATCAGACAAGGAACTGATTACAAACATTGGCCGCAAATTGCACA ATTTGCCCCCAGCGCTTCAGCGTTCTTCGGAATGTCGCGCATTGGCATGGAAGTCACACCTTCGGGAACG TGGTTGACCTACACAGGTGCCATCAAATTGGATGACAAAGATCCAAATTTCAAAGATCAAGTCATTTTGC TGAATAAGCATATTGACGCATACAAAACATTCCCACCAACAGAGCCTAAAAAGGACAAAAAGAAGAAGGC TGATGAAACTCAAGCCTTACCGCAGAGACAGAAGAAACAGCAAACTGTGACTCTTCTTCCTGCTGCAGAT TTGGATGATTTCTCCAAACAATTGCAACAATCCATGAGCAGTGCTGACTCAACTCAGGCCTAAACTCATG CAGACCACACAAGGCAGATGGGCTATATAAACGTTTTCGCTTTTCCGTTTACGATATATAGTCTACTCTT GTGCAGAATGAATTCTCGTAACTACATAGCACAAGTAGATGTAGTTAACTTTAATCTCACATAGCAATCT TTAATCAGTGTGTAACATTAGGGAGGACTTGAAAGAGCCACCACATTTTCACCGAGGCCACGCGGAGTAC GATCGAGTGTACAGTGAACAATGCTAGGGAGAGCTGCCTATATGGAAGAGCCCTAATGTGTAAAATTAAT TTTAGTAGTGCTATCCCCATGTGATTTTAATAGCTTCTTAGGAGAATGACAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAA bcftools-1.21/test/csq/EMN908947/EMN908947.fa.fai000066400000000000000000000000321467060157400203400ustar00rootroot00000000000000MN908947.3 29903 96 70 71 bcftools-1.21/test/csq/EMN908947/ribosomal-slippage.cmd000066400000000000000000000002711467060157400224310ustar00rootroot00000000000000{bin}/bcftools csq -f EMN908947.fa -g ribosomal-slippage.gff ribosomal-slippage.vcf --force | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%EXP\n%POS\t%REF\t%ALT\t%BCSQ\n\n' bcftools-1.21/test/csq/EMN908947/ribosomal-slippage.cmd.out000066400000000000000000000005071467060157400232410ustar00rootroot0000000000000013468 C G missense|ORF1ab|ORF1ab|protein_coding|+|2N>2K|13468C>G,missense|ORF1ab|ORF1ab|protein_coding|+|3R>3G|13468C>G,splice_region|ORF1ab|ORF1ab|protein_coding 13468 C G missense|ORF1ab|ORF1ab|protein_coding|+|2N>2K|13468C>G,missense|ORF1ab|ORF1ab|protein_coding|+|3R>3G|13468C>G,splice_region|ORF1ab|ORF1ab|protein_coding bcftools-1.21/test/csq/EMN908947/ribosomal-slippage.gff000066400000000000000000000010611467060157400224260ustar00rootroot00000000000000##gff-version 3 ##sequence-region NC_045512.2 1 29903 MN908947.3 feature mRNA 13463 13473 . + . ID=transcript:ORF1ab;Parent=gene:ORF1ab;biotype=protein_coding MN908947.3 feature gene 13463 13473 . + . ID=gene:ORF1ab;Name=ORF1ab;biotype=protein_coding;db_xref=GeneID:43740578;gene=ORF1ab MN908947.3 feature CDS 13463 13468 . + 0 ID=CDS:YP_009724389.1;Parent=transcript:ORF1ab;biotype=protein_coding;codon_start=1;gene=ORF1ab MN908947.3 feature CDS 13468 13473 . + 0 ID=CDS:YP_009724389.1;Parent=transcript:ORF1ab;biotype=protein_coding;codon_start=1;gene=ORF1ab bcftools-1.21/test/csq/EMN908947/ribosomal-slippage.vcf000066400000000000000000000005421467060157400224450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO MN908947.3 13468 . C G . . EXP=splice_region|ORF1ab|ORF1ab|protein_coding,missense|ORF1ab|ORF1ab|protein_coding|+|2N>2K|13468C>G,missense|ORF1ab|ORF1ab|protein_coding|+|3R>3G|13468C>G bcftools-1.21/test/csq/EMN908947/simple.cmd000066400000000000000000000002311467060157400201250ustar00rootroot00000000000000{bin}/bcftools csq -f EMN908947.fa -g simple.gff simple.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%EXP\n%POS\t%REF\t%ALT\t%BCSQ\n\n' bcftools-1.21/test/csq/EMN908947/simple.cmd.out000066400000000000000000000002171467060157400207370ustar00rootroot0000000000000013468 C G missense|ORF1ab|ORF1ab|protein_coding|+|4401N>4401K|13468C>G 13468 C G missense|ORF1ab|ORF1ab|protein_coding|+|4401N>4401K|13468C>G bcftools-1.21/test/csq/EMN908947/simple.gff000066400000000000000000000005761467060157400201400ustar00rootroot00000000000000##gff-version 3 ##sequence-region NC_045512.2 1 29903 MN908947.3 feature mRNA 266 21555 . + . ID=transcript:ORF1ab;Parent=gene:ORF1ab;biotype=protein_coding MN908947.3 feature gene 266 21555 . + . ID=gene:ORF1ab;Name=ORF1ab;biotype=protein_coding;gene=ORF1ab MN908947.3 feature CDS 266 13471 . + 0 ID=CDS:YP_009724389.1;Parent=transcript:ORF1ab;biotype=protein_coding;codon_start=1 bcftools-1.21/test/csq/EMN908947/simple.vcf000066400000000000000000000004061467060157400201440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO MN908947.3 13468 . C G . . EXP=missense|ORF1ab|ORF1ab|protein_coding|+|4401N>4401K|13468C>G bcftools-1.21/test/csq/ENSG00000173376/000077500000000000000000000000001467060157400166365ustar00rootroot00000000000000bcftools-1.21/test/csq/ENSG00000173376/ENSG00000173376.fa000066400000000000000000001123231467060157400207570ustar00rootroot00000000000000>4 4:121956748-121994196 ATTGAATACACCAAGGTAGCTGCTTGGGAAAATGAACAGTATATAATCTAATCTCTTTAA TTTTATGTACATGAATATAATGTATGTCAACTTTGTACATGAGATACATATAGTATTTAA ACATTTTACTCAACAAACAAGAATTTACAATAGCAATATAACTGACTAGAGGGCTATCAA CTTAATAATACTTAGATTAGATCTGTACTTTAATAGGAAAAGAATTTAATAGTTTACAAT CATAGAAACACTGACATTTAAAACAAGAATTTATAAAATAATTTATATATATCCTAGCAT CTACAGAGAGGAATGATTTGCATTTGTGGGTGTGTGCAATGAATGGCATATTTTAAATTT TTAGGTAATAAAATAATTTAGAAGCAGTTCATGCAGTGGTCAAAGCAAGGAATGGCAAGT TCCTTCAAGAAGCCCTCTATCTTTGACACCAACCGGCATCAGACACACACTAGGTACCAT GGGGCACGCTAGAACAAGTCTCCTTCAAGAGTTACTTATATAAACATCAATATACACACG TTGATATCCTTCCTTCCATAGTACAAGTACAGGTCACAACTTCTCTCAACTGTGGGAGTA GTCAGTTTATACTTAAAGTGATTTAATGTCCCTCCTGGAGTTCTACATAATATATCTCTA TAAGAAGGTAACTAACAGAACTTTCTAGTTTTCACAACCTTACTCTGATACTTTACAGAG TGCCCCCCATGTCCTATGACATAAACATCCAGCAGGTAAGATTTGCCAGGCTGAAGACCT TTAATTGTTTCTGTGGTCACTGCTTTCTGCAGGTTTTGACTGTGGAAATATTTACAGAGG ACCTTTTCTGACTTCTTCCTTATATCTGGTCCTAGACATTGGTTTTGCTCTCTTTTCTTC TGGTCTTCATTGTAGTTATCATCCACTTCTTTTTTGTAGATGCAAAACTTGTTCCTTTCC TGAGTGCCTAGCCAAGCCACGGTGGCTGAGGAACAGGTACGGAGCTTGTCAAAGGCTTTG ATTCTTGTGTCTTCAGGAAGAGAGGGAAATGACTGCTTAGTAGGCCTTGTGGTAGCTAGA ATTTTCAACATAGATGCTCCTTTCTTGTTTCCTTTCAGTCGAACGAGGTATTTAGCTTTA GGTTTTCCTCTAAGCTGAAACTGCTGAATGCCTTCCACATTCTGAGACAGAAGAAGTTTC CCATCTCTTCTCACTTGGATTTGGACAGCATCCAGACAAGAGTGAATAAAGAAGGTGACT TTTTGGTGAGAAGAGACTGGAGCAAACCGTAGAAACTTTGCTCCCTTCCTTTTAACAAAT ACATCTGTTATCTTCCCATCTTTTAGCTCGACTGTCTTCTGTTTGGCTTCTTCCTTGGTC CTGGCAAAGGTACCTACATAAGCGGTGCTCATGTTGCTGTTGATGTTGACCACAAATACA TCAAAGTAGTACTGCGTGTCGGGTTTCAGATCAGAGACGGTGAAGATGTTCTTGTTTCCT ATGCAGATTTTCTGAATATCAACCTTGGGCCTGGAGTAGACATGACGCCCCAGTTTTGGA GAAGGCTTTGCCTGGAAACTGCGTTCTTTACCTGAATTATCAGAAGGAAATCCAAAGTGG GCAAAGTCAAAGGGGCTGAAGTCCAGACCAGGTTTCGGTGCCATCATAAAAGCATCATCT GCACTCAGTTTTGCTTCCACTGCACAGAGACTTTTGAAATTGTGCTCTTTGTTGATGACC ACACAGTACTGAATGGGTTGTTTCAGCAAAGAGGCAGTGGGGCTTGGTTTCCAGGCCAAA GTGACCGTGGTGCGCCCCAGTGAGGTCACATCTACTCTTGGGTCATAGGGTAACTCAGGG TATGGCTGATCAGATTCTGGAGTTGTGGTGGCATATACTTTGAAATGTGTGTCTTTCTCT GTTGAAAGAAGATCCAACTGATATAAACCGGATGGGGAACTAGACGATATAAAATACTCA ACATCATTGCCTTTGTAGGAGAATAACTCAGTGCCTTCCTCATTAATGATCTGCTGCTTC TGCTGCTCAAGAGGTTCCAGATCACCTAGAAAATACAGGAGAAGCACAGGCTACTGTCAG GGCATACACTGTGGCTTGCCAACCTTAAGTTATCCTTTTATCTTATTTTTTCTCCGTTAT GAAAATAGTACATGTTCATAAGTAAAAATATTTATAAATGTATTCAAGATAATATTTATT TTGACCATTATACATAATGTTCTTATATATGTGTAAGGCTTCTCTGAATATAAATTATTT CTTCAGAGCAGAATCCAATTAGTAAAAATTTTAGGTCAGAGACTGTAAACTTTTGAGACA TTATTAATCCTAACTGTCAATCTGCTTACCAAAAGAATTGTATCAGTTTGCATTTGGATG GCCAGCCATTTTGCTAATTTCACGGCTGTTAGAAGGACTAGACAATCTGATTAAAATACA CAATATAAAGTACCAGTAAGAATATTTGGCTGGGTGTCATGGCTCATGCCTGTTATCCTA GCACTTTGGGATGCTGAGGCTGTAAGATTACTTGAAGCTGAACCTGGACAACAAAGAGAG ACCCTGTCTCTGTAAGAAATAAAGATAAAAAAATTAGCTGGGCATAGTGGCACATGCTTG TAGTCCCAGGTACTTGGGAGGCTGAGGCAGGATTGCTTAAGCCCTGGAGTTCAAGGCTGC AGTGAGCTATGATTGCACCACTGTGCTCTAGCCTGGGCAACAAAGCAAGACCCTGTCTCA AAATAAGATAAAATAAAATAAAATAAAATAAAATAAAATAAAACAAAACAAAACAAAATA AAAAAAGAATGCTTAAGGTTCAAAGTATAGAACGTGCACCCAGGAATAACACAGGAATAG TGGTAAAGCTAAACTAATTTTTTCCATATTTTGTTACCGTAAGTATCAGATATCACACAG ATATCAGTGTATAGCTTAGTCTCCAGGGCTTGGTGAATGACTGGGTAGCTACAGTGAGAA GAAACCTTTTCCAGCTTATCATTGCAGGTTGAAAGTGAGCTATACAGAATTTCCTATTCC TAAACTATGGGATAAACACAATCATCAAACAGATATATTAACATCAAGATTTGGCCAGGT GCGGTGGCTCACACCAGTAATCACAGCACTTTCGGAGGCCGAGGTGGGCGAATTGCTTGA GCTCAGGAGTTTGAGACCGGCCTAGGCAAAATAGTGAAACCCTATCTTTACAAAAATACA AAAAATTAGCTGGGCGTAGTGGCATGCACCTCTGGTCCCAGCTACTTGGGAGGCTGAGGC AGGAGAATTGCTTAAGCCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTACACCATTGCA CTCCTAAGCGACAGAGCAAGACCCTGTCCTGAAAAAAAAAAAAAAAAAGCCCATCAAGAT TTGTTTTCTGTATCTTGGTCTCTTTACTCCCCATACACACTTCCATAATTTTCCTAATTG CGATGTTTGCCCCTCTTTGAAACTACTATAGCTAGCCTTTGTAGATACGTATACATAGTT ATATATATATGTGTATATATATATGTATATATATATATAAAGACTATGTGTGTGTGTGTG TATATATATATATATATATATATATATATATATATATATATATAAAGACTATGTATATAT ATATAGTCATTTGTAGGGCACCCATTGTCAAGCCTTCACCTTTAACCTATGATGCCCTTA AAGAGCTTTCAGGGTGCCATACAAACTCTTCTCATTTCTCTTTTATTTTATTTGCTCTCT ATCATCTGTCTTCTTTAAATGCTTAGCCCACTCATCCTACTAACTTTGTTTTCATCTTGG CCTTTAACTGCTACTAAATGCCTCTCTGCTTCTCTGTTTCCATCTGTTATTCCCTGGAGA TCAGAGGTTCTTAACCTTGGCTGTATATTAGAATCACCTGGGGAGTGTGGCTAAAAATCC CAAAGTTTGGACCTCACCCCATTCCAATCAAATCAGACCTTTGCAAGATCTAGGCATCAG CAGTTTTTAAAGCCTTATACGTACGTGATTAGGATGTTTAGGCAAGATTGCAAACCACAG CCATAGAGGCTAGTCCAAACCTCTCCCCTTCTCCTCAAGCCGTCAATCCCTGTACCTGTC TCTCCTAACCTTTTATTTTATCAGGATCAGTGTCATCTGATGCCACCCTCCCACTTCCCT TATCTCCGTCTCATACCTCCAGATTCACTTGTGCACCCATGCTGCCTTTTCTTACTAACA CATAGAAGGTTGTATGTTTCACAAGCATTAAAACCATCCATTCAAAGGTCCAGGGGCAGA TCTATCCTGCTGCTTACCTGAGCCTTCCCCGCTCCTGTCCTCTGGCAGCTCCTGGAGGCT CAGCTTCCACTCCAAAGGCGCATCACAGGGCGTCACTGTGACTGATAATGGAGTATTGTC TTCTTCAACCACAAAGAAATACCTGTGGGAAAGTGGACCACTTTAGACCGTGGTAATTCT TTCTAACATTTACAATCAAGACTTACCAGAAAAATCATTTGGTTTTAATTTTTTTTTCAT TTTATAAATTTTATAAAATTTTCATAAAATGTCATTGTATTTTCCCTTAACACAGTTTAA TAAAATTGGCTATTTGACACAAAACATGATACAGCATTAACTGTGGAAGTCCAACAGCCC CAAGGATCTGCAACCAGATTTATCATCAACAAATACAGCGTGAAATAAAACACATTGAAC CCAAAGTATTTTGAGTTAAAAATCAACACTGACCTGTTGCCTGGTATTATTTAACACAGG CCCCGCCACTGCAAAATAAATCACAACCAAGAAAATTTCCAGGTTTGTTGCCCTATAGGT GCCATGCTTTCCATACATTTGGTGATAAATTTGTACATTAACTTGAGGGCACTCTGACAT AGTTGCAACTATTTCAAAAGAACATTTTCACAGCAACCTAGTTCTAAACTGTGTGTTTGT CTCTGGCAATATAACGCTGTATTCACATTTTTACATTAGTGACTTTTATTCACAGCTTTA CTATTTCATATCTTTTTATTTGTTTGTTTTGAGACAGTCTTGTGCTGTCTCCCAGGCAGG AGTGCAGTGGCGTGGTCATAGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAACGATCCTC CCACCTCAGTTTCCTGAGTAGCTGGGACTGCAGGCGTGTGCCACCATATCTGGCTAATTT TTAAATTTTTTTGTACAGATGGGGGTCTCACTGTGGTGCTCTGACTGGTCTCAAATTCTT GGCCTCCAGTGATCCTCCTGCCTCAGCCTTCCAAAGCACTGGGATTACAAGTGTGAGGCA CCATGCCTAGCCCATTTCATATCTTTTGGAATCGCATTATCTAATCACCATTTGAGAAAT ACTTTAAAAAGTAAAGAGCACTGTGTCAGTCAGTAGAAAGACACATTTCTCTAACACAGG TTTTCTGTTGAATTAAATAACTTAATGATTTTAAAACAAAATTTAAAAAATCAAATGTTC TACTCTGTGCTTTCCCCTGAGCCTTTATTGTAATGCCTTAAAAAGAATAAAAATATTGCT TAACTATAGAAATACCATATACTCTTACTCCAAATGACTTAGATGGTTTCATTTAATTAT CTTTCAAAACCTATAATCTTGCCAATGAGGAAAGAGTGGTTTCAGTTCCAGCAAGCCCAG AGTTGCTCATTGATTCCATGCAGAGAAAAGCAGGCTTTGCCTCCTGTGGATTGAACCTCC TGGATATCTCTTGCCTTCCTATTCTCTCCATAACCCTGACCAACACTGACCACCAGAGCC TCCGACCCCAGCAGTCTCTTCTGCTGGTTCCTTCTCACCTCCCTGAACTCTAATGTTGGG AGTGAACCACAGGACTGTGCTTGAACGTCTCTTTTCTACCTATGCTCACTCCCTGTGTGA CCTCATCCAGGCTCATACAATTAAGGAATTTTTCCCTAAGGCTAAAACCTAAAGCTCCGA TAGGACTCTCAGCTGGAAATCACATAGTACATTTGCTTTTTTAGGAGATTCCTCTTGCTG CAGTTTTAAGGAATGATTCGGAGGTGGTGAAAGTGGAGGTATGGGAAACTACTCATTAAT TCATCCAACAAACATTCCTTGAGATTTATTTTAGTCTTTGAGACTAAAGAAAAAGCATCC CCGAAGAAATGACTTTACATGTGAGTTGGGGCAAAGGAGTTCTTTTCAGGCAGAGAAAAC CACATCCCATAGACGGTAGGGTGAGTAGGGTTCAGAAACTAGAGAAGTACTTTGTGGTTT GAGCACAGAGTTAAGTGGGTAGTGACAGGACAAGAAACAGGTGAGGTAGGCAGAGGCCCT GTCACTACAGAGGTTTGTGACTCATACTCACATTTAGAGTCATTTCTTCAGGGATGCTTT TTCCAACTCACTCTGGATCAGGTCCTCTGATGCATTCTCAGAACGTCCTATACTTTTTAC TTTCGGGCACTTATTGTTACTTGTGACTATATAATTGTATTATCATTTGATTAATGTCAT TTTCCTCACAAGGGCCCTGTTAGGGTTCATTTATCACGCCTTTGTATTCCCAGCAATTAG CACAGGTTTCTGCATGTATGTACTTGATCAACATTTTAAAATAATTGAATTACTAAATAA GTAAATAAAACCTAAGAATCCTAACACCACACTTCTTGTTCTAGCCTGGTTCATACACCT AGAGTCTCCTTCTATCTGAAGATATAGAATCTGAATTGAAATACAAGTACTTCCCCCAGC CACCACCATTCAAAGATGCTTTTGGAGATGGAGAATGGGAGTGGGGCTGTGGGCAGACAA ATAAAGTGAAGACCCTATAAATGCAAAAGCAACTTATTCATATAACAGTAAAGTTAAACA ATCATCTAGACAAAATAGATGATTGAATTGTTTACTGTATGTGAAGTTTAATGTACCATA AGCATTCCTGAACAGTGTCAGAAGGCTTAATTTTTAATACAGTCTACTTTTTGTGAGTAG AATTTTGTCCCTTTGGCCAGATTGCATGGGAGTTATTAACCACATAAACATAATTGAACC TATCTATATTACAAAGGAATAGGTACAACAATATAACTAGTTTGGCATCATATAAGTAAA AGAGTGTTCAAAACTTCGTGTTTGATTTTAGGTTTTATGTGAATAACAGAGCTAAGCAAC GGCACAGAAGAAAACAATGTACAAGTTTGTCTATTACCTTCTGTTCTCATTTCACACAAG GAAGTAGTTTATTTCCAAAACTGTGTCTTAGTAACTTAAACGTAGGTCATAGGTGACCAG TTACAAATAAAACAATGCTTTCATTCCACAAGATAATGATTATGCATATAAAGCAGCAGG GAGACCCTCTAAGTTAACATTTTCATATGGAAGCACTTATGATTAGGGATAAATGATAAT TTGAATATACTTAACAATTTGACAGATATTTATTGTCTACCATGCACAAAGCAACTGTAG AAGAGAGTGACAATCAGAGATGACGGGACATAATCTACATGTTCGAGATATTTACTGGCT AGTGAGGGACACAGAAACATAATTAATAACTAAGGAAACATGGCCCAAATTATAGTGCCA AAGCTGAGGGATAAGCACACCATGAGCCATTTAGCCTTTGGAATTTATGTATAAACGTAA GAATAATTAATGCATTTGCTGTCTTTTTAAATTTACTGCTGTGCAACTTTATCTGGAATT TCTTTTTTTAGTTGGAATATCAACAACATGTTTGTGTGCTTATCATTACATATTTCACCC CTAGAAATGAAGTTTCTACTTGTGGTTATAATCCTTTACTAGCATAAGTCTGCTTTTACT AGTGTATGTTAACATTTTTTCCTATTGTGGATACCAAGGGCCTCAATAATCATTGGCGGA AAAAAGATAAATATAAAGAATGAATAAATGAGAGAAATAAAAAGAGAAAATGTTGTTTTA TAATGTCTCTTAATAAAAACATGGCGCTTTACTTTAAAAGTGTAATTTCTAAAACAGCTC TTACAGGCAAAACTTATTTAATTTTTAAGAAACTGGAAGACTAAAGAAAGATGAATCATT TAATTAAGTGATTGGATTACATAATGTGGAATGCTGTATTTAAAGTATATTGCAAAGAAG GCAGTGCCCAAGTGCATTTGGGAAATGAAAGTAATTTCTACAGAAAAATTTTGATTTGAT TTCACTCACACGTAAATTTCAAAGGACAAAATAATATGAAAAGCCAAATGTGCCCAGCAA GAACTCAGTTAATAGTTAAGATTAACTTGAAGTATTATGACTGCTTTGTATGCCTTTTAC TGTTTTCACAGACTCAATTTTAGTCAGGACCAAGAGAGCAAGTTCCTTCAATGTAATCAT CCTTTCCTTTTCTGCCTTCACTCCCATGAATGTCATTTAAAGATTCAAAATTATTTTATA TGTTATTGACAAGTCAGTTACTAGTCTAGTGTGTTCATGCAAACAAATAATTTTACTCGA GCAGTGCCAAAATGATAATCCGAACAATAGTTCACTCTAGTTAATGTAGGAAAACTGATC ACCTATCATCATTTTGACTAACCAGATGGAGATAAGACTGGGCCATTGAGTGGAAGGGGT TCAGACCACCATCTTCCATGATTACTGTTAATCAAAACTGAAAAGATGACTAATGATCTG ATATATCTCAATCTCTAGAAAATGGGTTATTGATGTTCTGAAACAGTTTAATCCTTTGGA ATTTCACTGTATCCCAGGTTAGAAGGAGCAACTGGTTTTGAAATATAATTATCCAAAGAT TAACTGTGTGTGCTAAACTTACAAAGGGAGAAGAGTTTGAGCACTACAAAATAGGTAACT TTAAATGTAATTAATTTATAACATATTATTTTTATTTTATATATATATATATTTTAAAGG TCAAAATATTTAGAAACTTTATGTGAGCCCAATTTGTTGATGTTGGAGTAAAGGTAAATA AACCGTGTCAGTTTTTATGACTGTTTAGTTTGATTCTCTCAGAATATGATAATATTTGTT GAAGAAATATTATACTCATAAAACATAATGCATTAAGTGTGGTGTCTCATGCCTGTAATC CCAACACTTTGGGATGCTGAGGCAGGAGGATCACTTGAGCTCAGGAGTTAGAGACCAGCC TGGGCAACATAGTGAGACACCATCTCTACTACAAATTTTAAAAATTTGAGGGGAAAGGTG GCACACACCTATAGTCCCAGCTATTCATGAGGCTGAGGTGGGAGGATTGATTCATCCCGG GATGTTGAGGCTACAATGAGCCATGACCGTGCTACTGCACTCCAACCTGAGCAACACAGT GAGACCTTGTCTCAGAAACAAAACTTAATGCAAACTCTTGAAGAATCATACATATTCATG AAAATTGATTTCACTTTAATCCTACAGAATCCTTCTTAGAAATATCCTACTGTACTGAGG CCGGGCGCAGTGGCTTACGCCTGTAATCCCAGCATTTTGGGCGGCCAAAGAGGGCGGATC ACGAGGTCAGGAGATCGAGACTATCCCGGCTAACATGGTGAAACCCCGTCTCTATTAAAA ATACAAAAAATTAGCCAGGCGTGGTGGAGGACGCCTGTAGTCCCAGCTACTCGGGAGGCT GAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTCAGCCGAGATTGTGCCA CTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAGGGAAAAAAAAAAAAAAATC CTCCTGTACTGAAAAGAAGAAAATAATCATTCCAAAATGTAAGAAATGCAAGCATTGCCT CCTACACGCAAAAGGAGATGACAATCAGCAAGAATCAAACAGCCTCTATTTCATAATTAG AAGTTGCACTGCCATGTTCCCCCTTACTTACAGAAAATCGGTAATGCCATTCATAGGTTG ATTTGTAAATTACCTAAACTAAGTCTAAAGGTTACTCTCTTTTTTGGAGGCATCCTTTGT GAGCTTTTTAATAAAGAAAATACTGCAGGGAGAATACCTCTTAGGTGTATCTCTAAAGAG ATAACTGCTAATTTCAGCTCCATCTGGAATTACTGACGAATCATGAAAAAATGCCTTGTC CCGGATCTGCATCTGAAAAAGTTCCTCATCCCGGGTGGGTAACTTCTGGGTCCTTGAGCT GAGTGGAAACAGGAGCCACAGCAGGCACCAGTGGAGCAGCACCATCCTGAGGCAACAGAA ATGACTACTTTATTAGTTCTGCAGGCAGACACTCAGGCAAGTCACAGACTTTCTAAAGGG TTAACACTATTTTAGCTTTGATGGAAATTTAGGGACGCATCATGTATTTTGGATACATAC ACATGATCTTCAAGGCAACTTTACTATATTTTTTCTTCAAACATTTTCATGATGTTAAAA ATAAATTCACTAGAATTTCAGACATTAAAAAGATTTTGAAATGAAAAGACTCTTGCTGCA TTAACTTCTCTGGGTATTCAGAGAGAAAATCCTCACTTCATTACAGCAGAAGCCTATATG GACATTGTAGATAACGCTATATCAATGTCTCAAAGCTTGCACGAAAATAATCTCTTAAGG TCAGTTTTTTGAACTATTATAAAAGTTATACCAATGGTTGGTTGGTATCATTGCTCAGCA GTCAAGTTGCTAATTGCTGATATGGTTGAACTATTACATTCAACATAAATCACAGAGACT CATTGAGAACCAGAAAATTATCACTGCTCAATTATTTTTATTCTTCCCTAAAATCTGACT AGGGGTTATACATATATAACTCTCTACGTAGTATTATGCTTTTTCCAAGATCAAATTTTC ATAAGTCAAGGATTTTTATAAATCATAAACTTCATCTCCTTCACAGATTAAGCAATTTGT CCAGAATCACAAGATGAGTTATTAGTTGATGTTTAGTTGTTATCAGGTACCAGAGTCTTC AACACAACGTTGACATATACACCTCTATCATTTTAGAAAATGGGCTTGAACCTTCACTCA CACATCAAGCCAGAAAGGTGTATATTTAGAACATTTGTCTTAACCTCCAGCAGAGAGTAC TTTCACTGAGTTACATTTTGGCATTTGTCACTGACTTTCATCAAAGATCCTCTAAGTAAT GATGGATCATTCTCTACTGCACATTGCTGTAGGGGTGTTGTCAAAGACACTGTCTTCCAC ATGTCTTGGTGTTCCCAACAGGAAGCCCCAGGTAGGCAAGTTCCTTGACATGACAGGTCT CATGAAAAAACTTTGCTTCCTCTGACCATTTGGTATTTTTTTTTCCTCACAGAAAGAAAT ATGTAAAGAATTGTTTTCCTTTACCTCTTTGACTTAACATACATCAGGGAATTAAAGCAT TAGAGAAATATAGTGTTTTTACATTGAGGTACTTTAAATAGCAAATATTTGTGATAATTC AAGATGAAGTGAATGCCAGTTTTATTTTTAAATGGACATTACTATAATCAACCTCTACTT AAAACATCATTTGATTTTAATTTTATCTTTCTTTGAATGCTATCAAAAATAGATTCAGAT TGCAAAAATATATAGTTTGAAAGAAATAACATTCTCTTTTTTACAATGTGGACATGAGAG TTGGATTTTTCACAACGAGCTTGTGCAAAATGCATTTTACTTTTCTCCAAATATTCTTTG CTGTTCTGTGTTCTGCGGTTTTCCATACAAAATATCTGCAGTGATCTAGAGCTACTATGT GCAAAGCACTGTTCTAAGTTCACGAGTTGCATTACTACTTTTAGTCCTCACAATAAGCCT GTGAAGTAGCTGCTATCCTATGCAAAAACAAAACTCCATTAGGTAAGCAGAGAAAGGATA CAAATACAGGTGGATCTGACTGCAGAGCCCAGTGTTCATCCTCTGTAATATCTCTCCAGA AAGCCATAATAACTTATTATGAGGCTTTTCTTTCCCACTCTTATTTCTTAATTGTATTGC AAGTGTAAGAAAATTCAACTGAGAGCTAAGAAACTTGATGTTTAGCTTCAGTTCCTTACT AGATGTGTGATCTTAGGCAATTCACCTAGCCACTCCGGACCTCAGTTTTTTGAAGAGTTT GGATGGGTGATCTATAATCAGCAATGCTTCTGAGACTGAATAAACTTTTCTTCCTAAAAA GCTGGCAGTTTAAGAATAAGACCAGGCCTTCTTAAGTTGCCTGAAGTAATCTCTCCCTCA GATATCCAGATGATTGTCAAGGAGAAATCCAAAAGAACTTGGGGATGTCAGTGGGAGCTC ATGAGAGTTGCTAACAGTAGACAAGGGCTATGTCTGCAAAAGATGGCTGGATGGATCAAA ATCAAGACTAGGTTGATATAATCTAACCAAGCAAGGACATGGTGGACTGACCTGAATGGG ACCTCCCTCACTGCTGTCTGTCCCTCCCCTCTGCTCCTCTTTTGTTTGGAGCTAACAGAA ACTGAAAATCCAAATGGCATTTGCTATGCTGCCTCTGTTTAGAAATACCATAGACATGCC ACATGCAATTCTACAAGTTTATTTCTCTTTGTAGTACCATCCCCAAAACTTGCCTTGTGA GAACAGACGAGGCCAAATAAAGAAGAAAATCTCTTTAGAAATAGCTAGAATTTCGCTTTC TGTACTTGTTAGAAATTTAGCAAACATGCTATCAGAGCACTTGAAAGCGAGATACACAGG CATATTTGCCTCAGAGCCACTCAAGGCTTACCTCCTTAGGCCCCATGTTTGCCCACAAAG CTGCCAACCACGGTGCCACAGTATGACTTAGCAGGACAAGCTGCCTAAGGACCCAGGGTA TCTGGGATATTTAGGTCAGCCCGAGTTGGAAAAATAGTGTCGATTGATAGGAACTTTCCC TGCATCCTCAACTGCCCTAGGAAAGAACTCTCTATTAAATCAGATACTTATAAAAAATGA ATTCTGGCTGGGCGCAGTGGCTCACGCCCGTAATCCCAGCACTTTGGGAGGCCAAGGCAG GTGGATCACGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCT ACTAAAAATACAAAAATTAGCTGCGTGTGGTGGTGGGCGCCTGTAATCCCAGCTACTTGG GAGGCTGATGCAGGAGAATCGCTTGAACCCAGGCAGCGGAGGTTGTAGTGAGCCAAGATC ACGCCACTGCACTCCAGCATGGGCGACAGAGCCTCCGTCTCAAAAAAAGAAAAAAAAATC TGAGATAAAAACAATATTAATAAATTTTGTTGTATACATGCCACATGCCAGGCATTCTTC TAAGTTCTTTATATATATTATTTCATCTAATGCTAGCAACAACACTATAATGTAGGCACT ATTCTTTTTTCTCATTTTAAAAATGATCAAAGTGAGACTTAGATAAGTAAGGTCATACAG TAAATACTATCTGATGTAAAAAATATGAACTATTTATTATAGGTGGCTTAAAATATGGTA AATCTGATTATTATATATTCTCCAGTTCAGCTACTTAACAAATTAATATTAGTAAACAAA TTCAAGTTATAGGATTATGCAGAGTAAGTGTTGGGAGGCAATTCTCCATGGGTCTCTGTG TTTGCTTTTGCAAGTACTTGGGAGCAGAAGTACTGACTGCTTTTGTTCCACATTATCTTT TCAAGGATATTTGTATAGTGAGCAGTCTTGGCAGATAAAGCCTCTGGAGCAAAGAGCAGG CATGGCTACCACCGATTATAGAAGATTTTAGGTCCCTAAATTCAGGGATCCTCTCTTGTA ATAAAATCCAAACATGGCCCAGTGCCCGCTGGCCCTCTTTGCATCATCCTGTGGGAAGTG GGGGTCAGGGAGCCAGTGGAAGAAAATAATGATACTCTGCCTGAGTAATACGTCACTCTG AGTAATAAAGTCCTTTGTCTCTGACCCAGGAGTATCTTGCCTTCTTCTAGCATCCATGAA ACTATGACAGACTAATTTATTAGCTTGCAAGTGGGCTAAAATCTCAAGTCTTTCATAGTC TTTGACACTAAGCTTCTATTTATTAAACTATTTTACTGGTTTACCTACTTTATTGGCTCA GGTAGATATTTTTATTTAGACAATCACCAATAGATAATGGACTGAAACTTTATCTTTTGC TTTATCAAAAACATCATATTTCCCAAACTAAAATTCCATCAGGCCACATTTTTTGTTTCT GAAACAGTTTTAACCATCTCAATTGCTATGCCAATTATGGGCAAAACATACTTTTCAAAA AAGTTTTAAAAATTTGTATGGACCCCAAACACAGGAATTTATACTCTGTCAGATTCTGGT TCTACAAATATTATCTAATAACATGCAACTACTGTTGGGGAAAAACTTAAATATTAGGGA GCACTGATGGCTTGTTCAATTTGGTCAGGTTACAGGCAGAAGTTAAAATGTATTTACAAG GAGCATTGAATATAGCTAATCAAAAAATGACTGTGTAGATACATTGTATATATTTTTACA ACTTATATTGACTGATAAAAAATTGAAGCTTTACATAAATATTATTTAAATGGTGGTTTT AAGATTTTACACATTTTTCCCTAACAATAAAATGTTCTGTCTCAGATATACAATTTAAGA ATTAGTCATTGAGAATAAACAAATGAAAATTCATTCTTGTTAAGCATAAGCCTTAAATTG CTTTATAAGAACAGACTTTTTTTCTAAGATTACAAAAGTGCCCTCTAATGGCATAACTTT TCCTCTCATTTCTTTTTGTTACTTCTAGGTAGGCAGAGCTTATCTAGATTTAAACTTTAC ATTAAATAACATCAATCAGAGTTTCACTTTAAGCACTTTCTTTTTTCATGGCCATCTGGT GGATGATGTAGGAAATGTGTTTGCACAGCAACAAATCTTGCTATCTTTCTACAATTGAGG CTTTAGTTCAAACATAAGCTGAAAGTTGCTAGGATAATTCCAAATATTTTTATTTTGCTT GGCAGATCAACTTGGTTGCACAGTATCCACAACCCAAAAGAACTTGGTAGTGTTACTCTG ATACTGAAAAAATTGACTTTGTTTCAATTGAAAAGTTCTAATGAATAAAAGATATAGATG CAATCTATAATTCTGCTATTTTTGTGTTGTCAAAGGCCTTCTTCACATTTGGCACAAGTC CTCAGATCCTGCTAAAACTGAGGTGAGAAAATAAAAATGACCTAATGATTTGATACAACT CAATCTTTAGAAAATAGATTATTGGTGATATGAGATTTTTCTTTGGAATGCCAATATCCT ACAGGGGAAATAAAATTGTCCAAAGGTTAACCATATAGTCTATACTTACAAAGGTAGAGA TGGGTTTGGATAATCCAAAGTAAATAACTAGTTTATATGGTGTATGAATATATACACACA CATATTTTTAGATCAAAAATGTGGAAACATTATGAGTTCAATCAGCTGATATTGGAGTTA AGGCAAATAAGTAGTAGTCCCCAAAGAGGAAACTTTTAAATATAAAAATGGAACATCTGC TGCCCACTTTCTTGCGAGCAGGTAAATACTATACAACCCAAGAGATATGGAGAAGGGATT CTTTCTAATGTTTTAGGACTATGGTGATGGGAACTTGCTTCTCCCCTTCATTTCCTCCAG TTTTAAAGAAAATGTCAGTGAATAGATTTAAAGCGTTTTTATTGTTCTGCAAGGAGTAGG GAGTGGAGCACATGATGGATAATTGAACATGTACAGACAATTCTAAGCCTTTCTTTAGCA TTAATTTAAACTTCATATTCTATGGAACTTTTAGATAAAATAAACTGTCCAACTGACCTG GCATATCTTTTTCCCACAAACCTGTGGAAATGCTTGTAAATTATAAAATGGTCAATGGTA AGCAAAGTAAAAATTTAAAGGGAGTTTGAGTAATTCATTGTATCAATTAAATACCCAGAA TTACCTCTATCATCACAAAAAAGCACAACATACCCTACAAAAATTCAACTTGCCCCAGAA TGTCTATAGCAGTTCTACTGCTGTCATTTTGCAAAATTTATCTGCAATTACATAAGATCA ACTAGTCAATTTACCCATCTGGGTTAAACCACTGGTTCAGTTAGTTAACATTTATTCTTT GAAATTGTATGAACAGTGATAAGAAATAAATCTGGCTAATTTTTTTTCCTTAAAAATCCA CTAAATGGTTTTACCACATAAAACAATTAAGACTTTTAAGAGCAGACTCTTATTTCAACC ACTAGAAAGCTTGTCTTTAATAGTTATAGACTGCTATTTGGCTATATTATCTGAGCAATT CAAACAATTGCAAATCTGGTAGATAGAAAGTTCTTTTGGGCTTTCATGTAAAGGTCCAAG GCTCTCAAAATAGAAGACGTGATATAAATTAATGCACTGTGACCTTTCTCATCACTGTAG CTTCCTCAGAACAGCAGCCAACAGCTTTACCTACCTGTGATAATATGATCAAAACAAATT CCTCCATCCCTCTATCACCAACAAGTTCTTTGCAGAAATGTATAAATGTAGTTGTGAAAA ATGTCATCAAGCTCTTACACACTTTACATATTATAAAATTTAAGATCAGATTCATCACTA TAAATATAACATAAAGTATAAAATTTGAAAAAATATATAGTATCACTGAGATTCGCTTAA AAATTATCTAATGTGCCTGATCATGTGCAGGCCACGAAGTTGAAATACATTTACAATGAC AAAAAAGGATGGGCATTCTGATTTACTTGAAGCAAATGTATAGAGAATAAATGAAATCTA ATGTTTAATTAAAGAGAGTGGAAAGTGCATGATTATAATTTGGCGAGAATAATTTCAAGG AATGGTCTGCCACAGAGATTTCTGTTATTTTCTTTTCCTTTCTAAATGCAAATATTTAGT CTTTTAAATTTCTATTTTCAAACTCAAGAGCATTTGTTTTTGTTTGAATCATCCATGTCA CATTTGATAATAAATCTGAAGCATTTGGTCCAGGTGTAAGAAAAAAATATATAGCTTTAG TTAGGGGAAGAGCCGTGTGTCTGCCATGACTTGCTGGGCAGCAAGCGAAGAGGACTGCAC ACTTTAATACTGAATGTCCAACATGTGCCAGCGTGGATGTACGGATTCCTTCGAGGCAAA AATGCAGCAATCAAAAGTTGAATTCCCAAAAGGTGTTTTATTTTGTTTTCTTTTGCAAAC AATGAAAATGTCTGAAGTTAGTTGTTCTTAAAAATCCAAATCTGTTAAAAATTTGAAGGA AATACAGCATATTATGGGCTGACATTTCCATACCTGAAAAGGGAGAAATAAAGCAGATGG AAGTAAAGGATTCCTGGTCTGCCCTGACGAGTGGTCTCTGGCACATGCTAGGTGAGCTCT CACTCTGCGATAACATGCCAACTTCTACCCAACCCAATGAAGTAGAGCCGACATTATGTA CAGAACTCGTGCACTAAAGCTCTCTAAATGCAGGCTGTCAGTACACAGTGACATGATTAT TAAGAGTTTTAGAGTTCATTATGTCAATAATCTACAGATTAGGGACCTGCACATGCATTT CAACTGCAATGATTCCAACCTCCCTTAGCACTTCTCTAAATGACTGCCAACTTTCCTTCT GGAAGGAAATTAAATTAATATAAAAAAGCAATGTGAAATTAAAACATGCCAAGGATTCGA ATAAAGTTTCCATTCTGTCATGCGCTCCCTCTGAGTCTCATGATGCAGAGTTCCTAACAG GGATAACGTTAGGGCATTCTAATTTAAAAGATGGCCAAGCCTACACAATCAGAATTACTT CAAAGAGGATCAGATTTTAAAGTAAGTAATCTTGTATTCCCATCAATATTAATGCCAATG AGAAGAATAATGAATAACAGAACTGGCCGAAATAAATGTCTCATAGATAGGAGTAGTCTG TAATTCAGGAAGCCAGACCCATTTTAGTAAAGAAAGGAGTAGAACTCTTAAAATGTATCA GATGGATGGTTAGAAGATATGACAAAGTTCAAAAGCAGTGTATGGGAGAATGCAAAGAAA AACTGGAACAGAATACTAAATACCTTCTTCCTATCAAAATGTCCTCTATATGTGAAACTG AGATAGCTGGGATAACTTCCACTGTCTTAGGTGATGCTAATGATTCTTAGAATAATGAAA GCCCCAAAGGAAGGAATAATATGCTTGGTTGCTTTTCTTGCTTTTGTTTGGCAACTAAGC CTTATTTCCTGTTGATCTGCAACCAAATGAAAATGACTTCCTGTGCAACATTCCCCAAAG CAGTTTACAAACTGCATACCTCATTCTCTACTGAAATTTAGCTAAGATGGAGCATGGCAG CGCGCCAGTAGCATTCAGCAACAGCACGTATCAGCCTGGAAGGTGAGGCATGAATTGTTG TGGTCAATAAAAAAATATTGAGTCACTGCAGTGTGTAGCACCATAAAAATTTGATTTTTT ATAGCCATTTATCCAAGAAGTTAACTCTTCAGTAAGTCACTCCATGGATTTCTTAGGATA CCAAAACCTAAATATGGCCAAAAGAGCAAAAAATGAAGAGAATAAGAGTTTTGTCAAATA TCGATGTCATACTCCAAACTCAACTGGGTAATGTGAGGTCTGAAAAAATATGTATCTTAG GAACTTAGAATCTATTTATGGGGCAAAATGTACCTGCCCAGCCAACAGAGTCCAATGTCA GCATTTCTACTCATTCATTATTTTTTTAATTCAATATCTATATAATACATTTTTGCTACA TGCCAGGTACTCTTCTAGGAACAGTGGTGACCTCAGGAAGTGAGTGTTCTAGTGGGAGTG ACAGGCAACACATAAACAGATACACAAGAAAATACTATTGCTGCTAGCTATGCTAAAAAT TAAAATAGGCTTCTGTGAAAGACAGTGTGGTGATGGGCATTTTAGATTGAGTATTTAGAG AAGTTTTCCTTGAGGAGATGACATTTATGCTGTCATCTGAATGACAAGAGGAAGCCAATG AAGCAAATAAATGTCAGGAGAAAAAGCATTCTGGGCAGAGAAATAGCTGGTGCAAAGGCA CCAAGGTTGCACTAAGCTTGAGGTATTGACAAAAGGAAAGGACATCACTGTGGAACACAG TGGGTGAGGGAAGAATGGAAGACCAAGTGCCAATCACATAGAGATTCACATCCATATTAA GGGGTTTGGATTCTGTTCTAAGCGTGTTGGGAAGGCCCCCATTGCCAACTTTTTTGAGAC AGGGTCTTGCTCTGTTGCCAAGGCTGGAGTGCAGTGGTGCAATCATGGCTCACTGCAACC TCTACCTCCTGAGCTCAACAGATCCTTCCGCCTCAGCCTTCTGAGTAGCTGGGACTACAG GTGTGTGCCACCTTACTCAGCTAGGTTTTTTTTTTTATTTTTGTATAGAAGGGATCTTGC CACGTTGCCCAGGTTGGTCTCAAACCCCTGGGCTCGGGTGATCCTTCCGTCTTGGCCTCC CAAAGTGCTGGGATTACAGGCATGAGTGGAAAGCTCTTTAAGCACAGAAAGGCCATGAAG TGATCCAAGCTTTTTTAGGAATAACCCTGTCTATTGTGCAGAAAATGGATTTCAGTGAAG TGGTAGTTTTAAAAGCAGAAAACAACTTCATCTTTCTGAAACAAAAAGATCAGATGAAGG CTACTGCAGTTGTCCATGGTAGAGATGGTGGTTTTTTCAGCTTTGTAGAGGAGATGAGGA ATAATGGAAAAACTGGGGATATGCTTTGCAGTTGGATTGCCAGAATGTGCTGGTAAGTTG GAGGAAGGAAGTGAGGAAAAAAGAGGAATAAAAAATAACACATTGATTATAGGAACGTGC ATATGATAAAATGACAAACAGAAAGTACTGCAAAGGTGGAAGAAATGAGAGAAATAAATT AGTTAAGCAGAATTTTCAGGTGGCATCAAATAGCCTGAATAGCTGTCTATCTTAGATGCA GTTTTAAAAACTGGTTATTATATTTAAGAAGGTATTAGAAGAAAGGAGAAAAAGAGGAAG GCATTCTCTTTAAATGATGAGAAACATAAATGAGGAGAGGCTACAGTGGAAATTAGTAGG AAGTGTGGCTAAAAAAATAAAAAGACTGATTTCAATTATCATGGTGGGAAATGGGATCCG CCAGATACATGGATGGTTGAAGAGACATATTAGAGAAAGGCAATACATACACACATACAC ACACACACACGCACCCCAGAAGTTGCTTCTTTGAACTTAAATTTTAAGTGAAGGGATGCA TATTATTTGAGGCCAACCCATTTGTTGAAAGTACCCAGAGAAGAAAGAAGTCCAAAGGCA TATTTTCGTCCTGGAAAGTGGTTGTTATGGTAAATGAGCAGGAAACAGAATTAAGAAAGA CAGATACAGAAGGTATGAAGAAAATCTGACAAGAAAATATTACTATTTGGTATATGTGAC CAGACCTCTTCATAAACTGTATCCAAACAGATAGGCTAAATAAAACCTGTGAGCCTTCCT ACAAACTCACACCTGCCAAATACCATATAACTTATGCTACTGGGCACTTATTTGGAAAGA AGCACCATCCCTGGAGGAATTCTAAAGGCAATGGAATAATCCGGAATGTAGCGAACTACA CAGGCACCAGCAGGGAAGTGGCAGATGGTGAGCTCAGTGAAGAAAAGACCAGGAGGGAAT TGACTGCAGTCACTGAGACAGTTGAGAAAACCAGGCTAGAGAGAGTAAGGAAGTGACTGG CAGCGTCTTTAGGATGGACACCAAGCTTTGATGTATAATACTCTACAGGGCAGGTCAGCA ATCTTTTCATACATTTTGCAATACACATGTTAAATGCTCACTAAATACTGATGGATCAAA TCGAACCATCACTATCTCTTCTGAATTGAGATAACTACTGGTTTTGTTTGCTAGTAACAG CAAGGATAAAACTGAAAGACTAAAACAGAATACTACAGCAAGAAAAAAAGATTCTAAAAA ACTATCAATCATTTCATTCAGGCACGACCTTGAATTTCTGCATATTTTCCATCTATCTCA GGCCATATGTACTATCTTCTTAAAGGATCTTCAACATTCAAAAGGTGTTTCTAGTTCTAC TTACCATATTAACAAGACAAGGTACTTAACATGATTCAAGTTCAAAGATGTTTCTGTTCT TATAACAAACCTGGTTTTAAAAACTGCCTTGGTGATTCTACTGGCAATGTCTGTTAAACA CATGGGTTGCATCCTCCCTAAAGTTTCCATCAAAGAAATCTTTTATAACCCAGCTTCCAG TGATGTAGTAAGCGATACCCACCAATAAGGCAGTGACAACAGAAAAGAGCAAGTGTGGTG GGATTATGGAGTGGGTAATTCCACAAATACAAGTAGGGCATTTACTGTGTACTAGGCACT GCCTGACGTGCTGCGAATGAGGCAGCGAACAAGATGTGTGAAGATCTTGAGCTCGTAGAG CTTATACTCAGTGGATAAGAGGGATGAAAAACAAGTAAAGAACAAAGTATAATTAATATA ATGATCCCAGAGGGCACTCTAAAGAAAATGATACAGGCTAAGGGACTAGAGAGGACCTGT AGAGAGGTGAAGACTGGGGAAGAAGGGGCCCTTCTAGGCTAAGTAGTCAAGAAACCCCCT CTGAAGAAGGAACATTTCAGCAAGGGCTCACGTGAAGAGTAAGCCATACAGAGTCATGGG ATTTTGGAACCAGAAGGGACTTTTAACAGATGAGAACACTGAGGAAGAGACAGCAGAAAG ACAAACACTGGTCTCCCAGTCTTTGCACCTGGGAACCTGCCTCATCTGAGTTAACTGCAA CCATCACCCACTAAGAGGGACACGCTGCCAAGCCACAGGGACTGGAAGACAGGCACTGGC TCACCAAGACCCGGCAGTCAGGTCAGGTGAGGAATAACTGGCCAGTGTTAAATCCAGGGA GGACACCAGATGCTCTGACGTCCATTATCAGATGAAACGGATTAGAGGCTCTCCGGCTCG CCCAGCCAGTCCCCATTGTCAGCATGGTTTTAGGGAAAGGAGCTTGGAGCTCAGCAACAT AAAGGCATATCTGACAAAGCCATTCCACTGAAGGAAGCAGTTTGAAAAGTAGGAAGTGTT CCTACAGAGGGAGGATGCTTCCTGACTTTCCGGAGTGAGATACCCAAAACAGAGCGCTAT AAAATCTCCGGGGAAATTCTTAATAGGATTGCGACAGTGTGGTGTTTACTTAGATGGTTT GCTATCTGAGCTCTCCCTGTACACTGTCAATAAGTCAACCAGTGTTTATTAAGTGCCTAC TGCAAGTCCCCTGGGAACCTTAGAGGCCAATAAGGTGGAATTACAGTCCTCTGGTGAAAC CAAAGACTTTGTTTCTTATGTTACTTTCTCGTCTCACTTGAATTATAGTTATTTTTTTAT TTTTCTTGTCCTTATAAAAAAGCTCTTCATGGGGCTTATATAACACAAGTTTATGAACAA AAATTACTTTTTACTCCCCTTTATATTCCCTACATAGCTGTTTTTAGTTTTCTTGTATAA AGTAGGCATTAGATAAATATTTGCTGAATTATACTGTTTTCAAGAAGCTAACAGCAGACA GCAAAGCAATCTGAAATACTCCCATCAGAAAAATTCCTAAGATTTCTGTATTGTGCAAAG AAGTTAGGGGCGGCTGTTTACCAAACCCTCAAGGCTAATTCTTAGCTTCAAATTCGTTCT CCTTCTGAAGCCCAGGCACCTAACCCTCAAGAGTGTAAAATAACTCAGCGGACACCTCTG CAAGCCAGACTTGAGAGTCAGGCTTGAATTTGAATCTGGGCTCCACTCCTTCCTCTGCCA GAATGCTTCCATGCCACTGTGACTGTGGGCAGATGATGCAACTGCTCCGAGCCTCGGTTT CCATGTTTGTTGACTGAAGTGAACAGTAGGTCCTGACGAGGCGGCTGAAGCATAAACGAA GATGCTGCATGAAAATCAGGACATGCCAGTGCAGCAGCGCAATCTTTCCAATTATGAAAC TAGGGACTTCCACACTATCTGACTTTTCAATCCCCATGTCCTATTAATCCTCAAATCCTG CCACTCTACTTGCTGCGTATTCTCCCAAATTTGTTCTCTTTTCTATCCAAATTGCCAAAG CCTCAAATTATCCACTTATTGCATCTCACCTAACTGCTCTCATACCCATTTCCAATATCT CTCATTCATTTTCTACAGTACTGACACTGGCATCTTTACAAACAAAAATCTGTTTCACTC TTCGAAAAAATTAAAAGTAAGATGGCTTCCCATTACCGAGAGGATGAAGTCTACGGCCCA TGAGGTCCTTCACTCTCAAGCCCTGCACTCTACCACACTCATTTCCTACAAGCTCCTCAC CCTCTGCTTCATATTCCCAGCAAGTGCCTCTAGCCTGGGCACAGGCTACTTCTTTTGCTA GGATGCCTTTACTGCCTCTCTGGGTGGCAAACGTCTACTCATTCTTTAAGACTCAGTCCT CAACAATGACAGAAAAATTTGGCTGTGCACTTTTTTATGCTCATATTTCTATTGAAGACC ATCTTAAATTGTTTGTACATATTCTGGAGTTTCCTAAGGGTAGAAAAGGAATCCTACATA TATCTACAAGTACTATAACTGATAGATAGTATTGACCACAGAGCCCAACATTAAGTAGAT ACTCATGACATTTTGTGGGTGCACAACGAATAAATGAAAAAGAACATTCAAGTTAACTAT TGTTGCTGATGTGTAGAATTTGTTTCAAGAGAATATAGGCTTAATAGCAAATAAAATATG AATGCTTTTGACAATTTTATGGGTGCTAAACTTATATATAATAGGCTATTGTGTGAAACC TAAGTAGTCTGGAAGCATATCTCTAATCTGATGAAGGGGACATCACGGATATCCACTGGC ATGGCTGCCATACAGTGATGGCATGTGCTGGATGGTCCGGGAGCCTGGTATAATTTTTCT GTCTTTAAGAACACAAAAATGTCCTGATAAGAAAAATAGCGTATTACTCAGGAGGGCCTC TTTCCTCTGAAATCATGTAAATTTTGGTTTGGTTAGGATCTATTCTGATCTGAGCACAGG AATGGCATAGACGGGTGCTTCTCAAATCTTTATGCGCACAGAAATCGCTCTTTTCCCGTT AAAATGAAGATTCAGGTTCAACAGGTCAGGGGTAAGTCCTGAGAATGGTCCTTTCTAACG GGCTCCCAGGAGACGTTGATGCTGACAGTTCATGGACTGCACTTGAATAGCCAGGTGATG GGTGGGTCTGTCTCTTCCAATCTCGTGATTCTCCTGTATTTTTATTTTGAAACTCCCAAA CTATGAAGACCTATAATCTGGTAATAGCAGCAGTAGGATTTTCATCTCTAGGATTTTGTT AGAACTTTCTAATCTTTAATTTTCACTGACTACCAAGTTTTAATATTTTAAACCTCTATT TAGGGAGAGGTATGAATGAAAGACATTGCCCATATCCTTTCTTTTTCTAAGAACTATTAT TATATCCATACTATTTCAGTTTTCTCTTTTCTCTACCTTCTTTAGTTTTTTTATTTTTTT AGTTTTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAAGTATGGC TCACTGCAGCCTTGACCTCCCAGGCTCCAGCAATCCTCCCACCTCAGCCGCCTAAGTAGC TGTGACTACAGGCACGTGTCACCATGTCTAGCTAATTTTTTTAGTTTTGGTAGAGATGAG GTTTCCATTGGTTGCCCAGGCTGGTTTTGAACTCCTGGCTTCAAGAGATCCTCCTGCCTT GGCCTTCCAGAGTGTTGGGATTACAGGTGTGAGCCACCGTGCCCAGCTTACCTTTTTTAC ATTAAAAAAAAAAGTTTATTCCCCCAAGCAGTTTGTGTTTAACACAAAGCCCACTAATGG ACCAGTGGACTATTTAGGAGACGGTGACAAGATTCAAAATTACACCAAAGTTTCTAGTTT GTTCATATACTTAACAGAGTTTGCAAAAACACTACCAATAAATAAAATGAGATCAAGAAG AAACCATTTATTACTACTACAGAATAATAAATTGAATAGAGTAAAAAAAGTGATGCTTCA TTCTGTGGGCCTAATCCCACATTTACCCAAATATCTGATGGTCTGGAAGCTTCAACTCTC CCTCATCTTTACCCCCAAGGTCCCCAGCAGTTCTTTTGATGGGTCAGCACTAAAGCCTAA GTGTTTATACTATTAAAGAATGTGTGGTGGCCTCCAGTGCCAAAGTACAAGACAAAACCA AAATAGTAATTTTTAAAAACTGTAATAAAGCTAACATAATCCATAGATAGATGAGTGAGT AGATGTACCAGGGACCTTAAAGAGTTAAAAGGGTTAAACTCTTTCCACGCCCTGGAAATA TTATTTCCAGAAAAAAGGGGAGGGCACACAAGTATGCAGTTAACTTGTTTTTGTAAAAGA AAGTAACTTAAAAGGAACAGTCTTCAAGTATGTATTTATTCTACCAGCCCTCTTGTAAAA TCCAAGGCCCCCCAAAACACACAAAAACACCTCCGGAAAGGTTAGAAAATATTCTCCAAA GACAGTGGTTCCTGATAATTTAGTAATTTGAGAGCTTGTTTGGAGGTTCTGGCAGGGGAG CGCAGCTACTCATATACCGTTGACCAAAGACCGGTCCTCCTTCATCGGGGATGGTCATTC TCTTTGGCCAAGTGCACAGCTTCGGGAGCGATGCACATGGAGCAGGGAGGAAGGAAGGGG ACACCCGCCTAGCCAGCCAGATCAGCTGAATCAACCCTGGCGATCAAAGGGTTGACAAAT GTCGCAGCCAGATCGCCCTCACGTCCACAATCTCACGATTTGGAGAAAGAATAAACATAT CATTTCCTTTTCCTTCTCTGTCTCTTCTCTCCTAGCTCATAGCTCAATGTCTCAGGTGAC CTCTTCTCATGTCTGAGTTCCTCTTCAATTCAGGATTGAGTCTTCTTGCAAACACCTGAA TTTATTTTTTGGTCTGTTCTTTACTCCCCCACCATCCCCCCACCAACGATTATGTAATTT TTATTATTTATTCGTGTATTTATTCATTTATTCATGCATTTATTCATTTATTCAAGTTTT GAAACAGTTTAAAGGCTGCCAAAGCAAAATAGAAAAAGATCACTCAACTTAGAGTAAGAT CTGAGTCAAAGATCTAAGTTGAAAAGGTCCTGATTAAACCATGATCGGCTTTGGTACTTT GAGTGAGCCTCTTAATCCCCTTCAAGCTCAATTACCTCATCTACAAAATGGAGACAATTA TTCCCAGGATTGTTATGAGATTAAATGAAATAATTGATATGAATGTTCTTTTAAAATTAA AAAGGTTCTATTTATCTTCAAATAGTGTAAGCCAGTTTCTCAGACTGGTTGCAACATTTT ATTCGGCAGCAAAAAACACGTCTTGACTTGCTCTTAAAACAGAGATATGTGAAGGAGTTT CAGCATCAGATTATTCCATCTTTATTTACCTATCAGGTAAAAGATTAGGACCTTATTCAA TTAGAGACTGATTAGAAGCACAGAGTTAAAGGCCAAGATGTCGATTTTAAAAAATAATCT CAAAAATAATTGTAAATTCTTAATATGCTTTTTGTTATCCTTCATACACCATATCTGAGG ACATCAACATTGTTTAATAAACAAAACTGATCAACACTGGTTCAAAGCCGAGCGTGCTTG GGCTTTTTAGGCACTATATCTAGCAAAGGATTTAAGATGCACGTGTTGAGATCAGAGCAC TGAGGATCAGGATCAGTTCCTGGGATGTTCTGCATTATTATTTCTGGATTAAGAGATGAT TAAAGAAAAGTACACTTTCAAAAGGCAAACAACACAGACAGATCCCACAGTCATTTTCAA TAGTTTATAGCAAATTGTGATGAAATAATACAAGCATGTAAACTTACAACAATTAGAGAG ATGACAAACCACAAGTACTGATACAATATGGGAATTCAGACCCACAATTATGTAATCCTT TCCCCCCCAAGGAAGTAAGATACACAGTTAGGTGTGGTTTTTCTTCTCCTATTTTTTTTC TTTTCTCTTTTTTATTTTTTTAAGGGAAGCACTAAGGAAAAGGCTGCAGCTGGTGAGTGT CGCGGTCAACAACGTTCAGTGATCATTACACAAGATAGAGCCTGCCAAGAGAAAAAGAGA TCTCGAAAATGCCTGGTGGTTGTCATTGCTTTGTACGTGTGAATAAACTTTAAATGTGGA AAATGTTTTAAAAAATTATAGACTGAGTTTGGCTGAAGTGTTGAGTGTATAAATACTTTC ATTATCTGAACTTATTTTTCTTATTAAATTTTAAAGGGTTTTAAACTTTGGAATTTTTGG AGTATCTTTTTTATATATGTTTATAGGCGCTCTTGTTTTGCTGAAATGTACAGTTTCATC CAATTTTTAAAAACTAATTTAAAAATAATTTTAAAAATCTTAGAACTGATCTAACCTCAA CTCTTGCCTCTCAAGAATGCCACATAATTAACATTATAATGGAACAACTTGATAGGTAAA TTACTAATTGCTACTAATTTCACAGAGGATTCTGCAGCTTCTTGATTTTTCAGTGATTGC AGCTACCATAATAATTGGAATATGTTTCAATATCATGGGTTATGTGTCTCTAATAAACTT TTGAGTTATTTTTCTAATCCCAAATTTTCTTATTGGGCTCTATTTACTGAAGAAAATATG TTTTATTATTTCCTTTTTCCGATAACTTGTCTCTAAGGTATGTGAAAGGCTTTGTCTATT ACACATATGTGCACATAAACACACACACACACACACAGAGTGAGAGAGGAGAAATCAAAC TCAACAAATAGCATATCTTAGAACATTGTAATACCCGGATTTGAATGACTGGGTTAGTAG GACTAATTAAAAGGAGGGCTGAAGAGAGAAAATTTGACTTCAACAGATGATTTCAGGCTA TAAGTAGACTTAATAAAGTAAACTGATAACCTAGTTTACCTTTTATGATTAGAGGAGAAT CTATGCAAATGGTGATTGGGGGTGTCGGGGGGGCCATGGGAGGTTTACATCAGAACCTGC GCGTGTTCAGAGACTGATGTTCCACTTCACTTTCAGTGATTTCCCCTGTTAAAAAAGACT AACCTTCTAGAAGGAGAGATATGGGGATTATTTATCACTGTTAGCCCTTTGTGCCATTTA GAACTGGTGCTTTTTACTCTCAAAGGTAAGTTTTGTTTCTGTTTTACCTGAAATAATTAT CTACAAGTGAAAGAGTTTAATCAGTTTCCCCTTTAAAAATTCCCTAAGAAGTTAACTATT ACCAAAAACAAACAGTGAGTGCATAGACAGTCTACAATTATGGTCTTGTGGATTTAGGCT AAATAAGTGGTATTCTGAATAATTAAATTGTAAAAAACTTCTAAGCAAATTGTCCAGACA AATTAATGTGGCAACTAATCTCAGCTTAAGCTTTTAAACATTTTCATCAATTTTGCTTCT AAAACCAAAGAGTTACAACTTTATTTAAAAAGTTTATGTGAGTTTAGGTAAGTCAGATTT ATCAGGAGTAGAAGGATAGAATATCTTCCTCACTGGGTTGCTGTGAGGGTTAAGGAAAGT GATGGATGTGGAAGTACCTTGTAAACAATCAAGGGTTATACAAAGATATATTATTATTAT TAATAAATAGAATCATTTCTGCTTCCATTGTGAAATTCAAAGCATGGAAACAACTTTAAC ATTAGTTAACAACTGACAACATTACTAAGAAAAAATATAATTTCAAAGAAAAACTTCAAA ATATAACACAATATACATAAAAAATGTTGGATGGAACTTTTTAAACTCTCAGATTACTGA TATTTTCAAAACATAATGGGGCACAATATGCATTTATACATAAAAGAGGAATTATGAAAT ACCTCTACAAATAACAGAATAATATTGAAAATAGTGACTAATTTGAGAGCTTTTTCAGCT TCTTGCTCAATTCTTTTCAACGTCTCTCACTCAGTAATGTGTGGTCTGAGGTCTGAGGTC TCCAAACCTCTTAGAATTGTGATTTAAAAAAGTGTGTATGCGTGTGCGTGGGTTTGTGTG GGTGTGTCTGAATACACACATACATACTTATAATACATTAAAAAATACTTAAAAGCTCTC TACACTGGGATGAGTATCATAGACAATTACAGTAGATATAATTGTACATTTCAAATCTTT TTCTGGTTAATTTCAGGGGTGTTTTATAAACAGGGCTGATTATAATGTCATTATTATTAT TATATTTTTAGAGATGGGGTCTCAGTATGTTGCCCAGGCTGGACCGCAGGGGCTATTCAC AAGGGAGATCATTGTGTACTACAGCCTCAAACTCTTGGGCTCAAGTGGTCCTCCAGCCTC AGCCTCCTTAGCAGCTGGGATTATAACTGTGCCACTGCACCTAGCAGAATGTCATTATTT TTATCTTGCATTAATTTTGCTTCATACATGCTGTCACCTCTGCCGTTCTTTGTTGTTCCA TGACCATCTGATATCCTGAGTAAGAGTGCTTTCGTTAATTGATATAGTATTAAGTAATAT TCACAAAACTTGATTTCATTCTTTACAGATAAAAGTGACTATAAATAGATCTTCTGGTAT TTCCTTCTTACACCATAATGAGGCAATCTTTGCCCCACAATGAGGCAAGGAGGGCACCCC CTTTTAAAGACCTCTGCTTTACAAGGTTGACACTAACAGAAGCTGAATATCTGTTCAGTA CGATTTTAGAGGCAATGGGCAACCTTCGATTGTTTAAAAGAGTATCTTGTATCCTCCACT TTACTGTAATTAAAAGACAAGCTTTTAAATGCAAATATTCACTGGGTCTAACCTTGCAAA GATAATTTCAAATGTCCTTTTCTAATTCCTGGACAGCTTCTGATAGTGTCAACCTTGTAA AGCAGAGGTCTCTAAAAGGGGGTGTCCTCTTTGCTTCATTGTGGGGCACAAATTGCCCAT TATGGTGTAAGAAGGAAATACCAAAAGATCTATTTATATTCACTTTTATGTGTAAAGAAT GAAATACACACACACACACACACACACATATATTTTACATATGTTTTATACATATATATG TATAAAATAACCCCTTCTAAAATGTTGTCTTAAGTGATCTGGCTTTATCTAGTTATTAAA ATATCTTTGTAAAATGTTAGCTGGTATCAGTTTACCCATTTCCCATTGCAGAGATATTTT CATATTTATAGAGGACACTGAAAAATAAAATTAATTTAAAAGTTAAATATAAATTAATTA ATGTAAAAGTTAAAAATAAAATTAATTTAAAAGTTAAAAAAAAGCATATTTTTTCAGGTA GTGTTTTGGTACCCTGAGAGGCCCTGGGAGCAGGGTGGCTTCCCTGGTACCTCTAAGGCC ATCTCTCATGTAACCCATCTGTTAGTTCTATTAGTATGGTGAATCCTGCTATTGCTATCA TTAGAGTGTTAAATGTTTATCTCTCATTTAAGAGGCAGTTTTCTTTTTCCATAAAAAGTA ACATATTTTCATAGCACCCGAAGAACTAACAATATCAGAGACTCAGGGAGGCACAGAGTT AAACGACTGATGTTTTTCCCCAGTTTACTACGTGTCTTAGCTAGCGCTGGTGTTTCTGAT CTGTCCCACTGTTGGCAACAAATCTCTCTTCAATTACAGGATCCAGCAGTATATATTTCT AATATATAAATTATAACCATCTACACTCCAGAAGTCACCATACACTTGTAACAGCTAAAT TGGACAAAGTAATCCTAAATAAATCAATCAGGCCCTATTATACTGGTTTTTCTCTCTTAA ATATAGTATTTTCAAGTAAGTACCACAACACTACCCCTAACTGTCTGCCAACAGTTTGTT TGCCAACTGCCAGGATAGGGCATTGTCTGTCTTGTATATACCAATTTGTTCATAGTTCCT ACATTATAAATTTTAAAAACAGTCATGGTGATTTCAAAAACAAGATGTCATATTTTAGAG GTCTAATTATGAGTTCAGATTTTACTGCTTATTTTAGAAAATGTTAAATTTCAGGCTCAT ATTCTATCTACATCTGTGTATATAACAGCATTGCCTCAGAAGACAAGATATGGTGATTTT CAGTTGTTGATAAAACACATATTTGAATATAGTCCATATTTTTGGCTATGTTTTTAGATT GTGGAATATATGTTCTCAGAGCACACAGCTGGAAGAAGAGGGTGTTTACCTTGATTTCCG CTTAGAGAGAAGAAACACTGACAGAAACTTGTACAGTCTCCATTTACTTCAGCTGGTCAC CACTATTTGTGATATTAGCTGAAATCATTCCAATTAGAAAGCAAACGTGCATGCATGTTG TGAATTGTTTTTATAATTTGGTTTTTATATTTAAAAGTCTCCACGCTGTGGAGGCAGTGT CTAAGAGTTCCACTCAAATGAGTTGATTCCCAATCACGCGTAATCATATTTTTATTGAGT ACTCTCCAAACTTTATATAACCTTACCATTATTCCTAAAAAAGTTTTTCTTTTAACTATA AAAAAGACGGCAAATTATTTTAAAAGAAGAATTAAAAGAGACATTTGATAAATTATACAT TTATACTACTACCTCTAGCCACATTTTTTTAAAGAAAAGATTCATTTTAGAGTTTTCATA AGTGAAGCTAAAAATAAATACTTCAGAGAAATATATAAAATATTAAATGTGTCATGTTCA AATTTGTTACAGAAAAAATTAACAAGCGAAAACCAAGACCTATTAACTAACTTACTAAAA TAAATCAGTTTCCAAAGGATATGGAAGTTATTGAAAGAATGATGACATATATCTTGAAAG TTTCTATACTTTTCTCATAAACTTGAGGTTTGTGGACTTTAAAGTGAAGTTTAAATCAAA GTTAACTCAATGAGTTCCTTGAAAAAAATTGGCATTGTAATAGGGCCAAATACCCAGCTG TTCTGTGGCCAAATTTGTCTCTTTATCCCAAAGTGAAAAATCTACAGACCATTTTGCTAG TTTGCTTTTATACCACATTGATCAAATTTGTTACCCTTAATTTTTAAAATCAAAACAAGC CACAACTTTTTTTATTGGGGGAATTAACATTATATATTACATGTTTTCCAAATATTTCAA AAGACTAAAATTCATGTGTTTGTTGGTTTGCAGTTTTTAGTAAAGTACCAGAAGGAAGGG GAAAGGTGTGGATATTGCTTCTTTGGGTTGTGTGTTTAGGAAGGAAGCAGCCAAGGATAC ACCTGCTTTTGGCACTGGCTTAGGCACTGGTACAGCAAATGCCAGGTGTCATCTCAGAAG AGGCAAGAAATACGTGAAATACACACAGCCAAGCAAACAGACTTACACTGAAATGGTGTG ATTTTCAACAAAAATATAACTGAGTTTATGGTCAACATACCACCATGTGATACAATAAAG TATTAGCATTCTTGTTTTTCTGTCTCATACTACATGATTATTTTTTAACAACAGCAGCAA AGTATTTACTTTTTTTTTCTAGGAGGAAATTAACATGGAAGCTTGACTGCATGCATGCTG AGTGTCACGTAATGTTACATTTGTAATACAGTGGAAAAATACAGCAGAATTTATCCTAAC TTCAGGGAATAAAATGCAAAGTATTTTAAAATAGAGTATTTAAATCCTGGAGGATTTGAT TTTAAAATCAGCTTTCAAAGCAAAGATTTTGTGGGGTTTACTATTTACTATCAACCACGC TGTGGCTTCTATTAAATGATTATGAGCCCACAGGGGAAGAATAAATTGTGTTCTTTAGAA TAATCATTCTAAAATAAACATTTAGAGGTTCTAGATATTATTTCAGGGTCAAATGAATTA GTTGAACTATTTTGTTGGTTATATTGGGTATCCCTGCCTTTGACCCAATACAGATGACTA TGAGACATATTTTCTTCCAAGTGATTAGCTGATGGCCACTGACTGGCAAGGTTCAGCTGC TACTATAGGTGTATAGGTCCCCAAAGCAAGACCTGACAAGAAGGCAGGTAGCAAAAAAGT GAGACAGAGAGAGAGAGAGAGAGCACTACTTGGTCACTATCGACCACCTTATCATGGAGA AACTAAGGAAAGGAGATTAAAATAATCTTAATTAGCACATATGATGTGTAATTCACACTC TGTTCCTATGCTCTCGGTTGATTCAGTCATCATTATTCCATTTCCAATATCTGCTCATCC ATCATACCAAAATGATAAGTCCTAACGACGACAACAAAAACACATTCAGTTTTAAAGTAA AAATTCTGACCTCTAGATAGGCTGAAGAGAATTGCTATAGAAATAAATATAGGAAGAGAA GAGATACACTTTATTTCTACTTTTCTCCCCTTCATGTCAAATAATTTGTTAGAGTTTTAA AATACATTTTTCTCCCTTCCACAACAGAGTCTGGTCGATAAATCCAAGTGAGAAAACTAA AATCTGAAACAACAAGGTTCACGCAGCCAACTAGAAAAGTCTCTACATTAAGCTGACGAC TGACCTACTGTGGCTATTTCCAAGGTAGCATTCCATCGACCTGGTATTGGCAATGTTGTG ACAATAGTCTTTACTCTTTAACATTCATACTTCACCATATGAATGTTAAACAGACCCAGG ACAAATAAGCTGAGGGTGGGGGCTTCTCTTGTCCTTAGAAGGATATTTTTCAATTACATA TTTTGTTACATCCTAAGAGATAAAAGCTGTATCTGCAAGTGATTAAAAGATGTTTTATAT TCATGGTTTCATTTCTGCTGAAATAAATGCGTAATTTAAACCAAACATAATTCATAGCAA TTTAGGCCTATTACAGAGTTCTAGCTTCTTTTTTATGATAGTTACTAATTAAAACAGAGT GTTACTGCCACACTAAGCCTAAGTCTTTGACATACAGGTTTAATGAATAAAATGTCCTGA CACAAAAATGAAAGCAATAATGCAGACAAGGCTGCAAGCTGTTATGTTTCAAGTGTGTGG TAAAGATTAAGGGCATTCACTGAAGTGATGAACTGTGCAGAGAAGGACCTTGTAATTTCT TTCTCTAAAGGAAGAAGTAAAGGAATTTTTAGAGAAATCTGAAATAGTACTAATTTATCT AACTCCTAGGCCCCTCATTCCCAGTTGTCCCTCTCTCCCCTCCAAGAGTTTAAACTCATA AGAGTCACTTCTGAGGAATAAATGATGGGGTATTTTAATATAATCCTGAATATAGGTTTA GATTGAAAATGGGAATTGGGACCATAATTAATTATGTTGCCAAGTTTTTTAAACTTTAAG AAGACAGATGGAGGCAAATGACATTTTATAAGAGTGCAACCTTCTAAAAGATCATAGATT AAAACTGTGGTAAAACGACAGTATCTTTTTTGACATTTGATTAATCCCATATGCAGAATG ACTGAAGAATTAATACGGTTTTGGTGTTTTCACTTTCTGAAACCACTGTAATAAGAGACT GACATAAACTCAAACCCCAGTATAAACACAGTCTGAGCGAAGGTTGCGGCCTTATTATCA CTCTTAACAAACAATAATGAATAATCATACCGATCGCCCTCACTACACTCTGCTTTATAT ACATATTCCCTCTCGGATCCATCCATCACTTCTTTCAAGATAATAAAACAATTCAATCCC ATCAAATCCCCTGCAACCGCTCCCTTGGGAGGGATGTTTTATCTCTACTTCTCCGAACCC AGGGAGGATTTTACTTGTTTGAAGGGGGCGGAGAATGGAGCGGAGTCCTATTTATTTCCA TTGATGACTCCCCTGGTTCTCACAGGCGCTCAGGGACCGGGTGGGAGGAGGAGAGGAGGA GGTGCGGAGATTCCCTCCGTCAGAAAAGAAAAAGGGTTCAGGAAGCGAGGCAGCAGGAGG AGGGGTGGAGGGGGGAAAGAGAGGGTAGTGTGTTTGGGGAAAGCAGCAACTAAATGAAAA AATAAACTCTTCTTTGTGATTTAGCGGGATCGACAGATGAGAAGCAAATTTATCAACCCA ACAAAGTTGCTAAAAAGAACTCTGTAAATAAATTTAAAGAAAAGAAGGAAAAAACATAAC AACAACAACAAAACCCAGACATACACTCAGGTTCATTTCCCGCTCAAGGTCTTGGTTTTA GGGAGCCACCCGTACCCAAGAGCAAGAAATGGACAGCGCCCCGAAGGGGGCCAGGAGGGG AACCGCAACTTGGCCGGAGGGACAGCTCAGAGACAGCGTAGAGGTGCCCGCGGCAAACTC CGAGGAGCTGATGCGGGGCGGGTCCGGGGAACTGCCGGGAGCTCTCACGCCTGGGCCTGG GATAGGGTGCGGGCAGAAAGGTGAACCGAGAGCGCACAATGCAACGAAACCGCACTCCAA ATTCAGCAGTTTGCAAAGTGCCTCCAAGAAAACAGCTGGGACCTGCAATCACTCGTTCGG ACTCCTAGGTTATCGGGGCCGCGGCGACTCCGCTCAGTTAGAAAGGTAGCGCGGGTGAGA GCGAACCCCAACTCACGCACAGACAGGACGAGGGCACGAAGCCGAGTCTCCTGGCTGGGG CCGTAGGGGGCGTCACCTCGGTGGCCGCTCTGCTCTCCGGAAGAAAGTATGAGCCGGTCC CAGGCCACCTCGCTCAGCCCAAGGAAGTTTCTATAACGATGCTCGCCTACCACGCAGAGG ACAAATGAGGAGCCAGAGCGGTTGGGGGTCGGGCCAACCGAACTCCCGGCCCCGGCTGCG CAGCTCCCAGACGCCCACCAAGAACTCGTGCGCTGCCTGGACCTCTAGCTTTTCGCCCTA CACGCAGACGCCCTCTGCAAAACCCCAGTCCCGCAGACTTTCCCTAGCGGCGGGCGGAGG GCATGAACCTGGAAAGGGAGGCAACAGCCCTCTTGGCAGGCGGGCAAAGTAAGTGTCCAG GCTAAGTCCGGGATAAAGGCTCCGCGGCTCCCCAGACCCCACTGCACCCCGAGCTCCCGG GTCCCAGGTCTTCCCCGCCCTTGCGCTGTCTGTCCACCTCCTCACATCTCTCCGGGCCGC CCAGCTTCGAAAGCAGCTAAATTAAAAACAAACAAACAAACAAACAACAACAACAATAAA AAAAAAAAAACGAGGGAAACCTGCTCCTGCCCCTCATGCCCTCAGCTCCTACGGATAGGG CGCCCTTGAGAAGCTTCTTGGGCCTTGAAGATTTGGGGGCGCGTGCCTCGAGCCCCCATC TCGGATGACCCTTCGGGCGTGAACGCTCCTTGTGCTAGGTCTCAGGGTGGCGGGCTAAGG CGTCGGGTCTCTGGGGCATTGCTTTCCTCTCCCCACTTACCTTAAAAAGATCTGTTTTTC GTAGGGAAAATAGAAAAAAATCCCTCCCCGTGGTGTGGTGTGCGAAATAGTCCACGTCCC CGGACCCTGCCAAGATGCTAAGCACCAATATCCAGGAACGAGAAGCCTGGAGGGCGGGGA CGGAGGCAGATAAAAGAGAAAAATTCAATCCGCTGAAGTGTCCCAACTTTGCGGTCGGCA CAGCAAACTTCAAAGGCGGGCGAGGGCGGGCGGCGCGCGGTCGCCGAAGTTGCTGCGAAG TGGAGTAGGGAGCCGCGCGGGGCTGGGGAATCCCGGGGCAGCGCCGAGAAGCGGCGGGAG GTCCTTTTAAACTGCAGGGAGCGTGCGGGGGCTGGGCGGCGGGAGGATGCCGCAGCGACC CGCGGGGCTGGCGCGGGCTTCGCCGGCCGCCGCTAGTCGCACAGGCGCCTGGCTGGAGCG CCGCGCGGGGTGCTGGGAGAGCCGGGCGCACGGGGCGGCAGCGGCCGTGGCGGGTGCGCT GCTCAGTTAGCTCCACTCTCTCGCGGCTGGAAGTGGGGAGTGTGTGTTCGCTCCCGAGTG TCACTGCTGAAGCCCGGAGTCTCTTCCCCTCCCAGCCCTAACCCCTCCCGCCTCACCGCT GCCCGCCCGCCCCCTCCCTCCTCTGCCCGTTGCCTCCCCCTCCGTCCCTCCTTCTCTCCC TCCCGCTGCGCGCCAGCGCGCACGCACACACACACACACACACACACACTCATACACATA CACACACTCACACACAGACACCCTCTCCCTCCTTTTCTCTCTCCCTGTAGCCCTCCCTCC CTCTCTTTCTCTCACACACACACCACCCTGCTCAGCGACCCAGCGCTCCCCAAACAGGAC CCTCGCGGGCGGCATCGCGAGGGACACGCTGCTGTCCTAACCTTAGCGCCACTCGGGGAG AATGAAGGAGGCCCACCGAGCCCCCGACAAAGCTGCAAAACCCAGGAGACGCGCACGCGG GACCATCACACTGTCAAGCAGACCGGGGTGCACAATAGAGGGAAACTCTGGGGTTGATCT GGGGGCAGG bcftools-1.21/test/csq/ENSG00000173376/ENSG00000173376.fa.fai000066400000000000000000000000211467060157400215040ustar00rootroot000000000000004 37449 25 60 61 bcftools-1.21/test/csq/ENSG00000173376/ENSG00000173376.gff000066400000000000000000000063441467060157400211400ustar00rootroot000000000000004 ensembl_havana gene 21 37429 . - . ID=gene:ENSG00000173376;Name=NDNF;biotype=protein_coding;description=neuron-derived neurotrophic factor [Source:HGNC Symbol%3BAcc:26256];gene_id=ENSG00000173376;logic_name=ensembl_havana_gene;version=9 4 ensembl_havana transcript 21 36926 . - . ID=transcript:ENST00000379692;Parent=gene:ENSG00000173376;Name=NDNF-001;biotype=protein_coding;ccdsid=CCDS3717.2;havana_transcript=OTTHUMT00000256532;havana_version=2;tag=basic;transcript_id=ENST00000379692;version=4 4 ensembl_havana three_prime_UTR 21 671 . - . Parent=transcript:ENST00000379692 4 ensembl_havana exon 21 2065 . - . Parent=transcript:ENST00000379692;Name=ENSE00001740431;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001740431;rank=4;version=2 4 ensembl_havana CDS 672 2065 . - 2 ID=CDS:ENSP00000369014;Parent=transcript:ENST00000379692;protein_id=ENSP00000369014 4 ensembl_havana exon 4338 4462 . - . Parent=transcript:ENST00000379692;Name=ENSE00001611953;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001611953;rank=3;version=1 4 ensembl_havana CDS 4338 4462 . - 1 ID=CDS:ENSP00000369014;Parent=transcript:ENST00000379692;protein_id=ENSP00000369014 4 ensembl_havana CDS 10058 10245 . - 0 ID=CDS:ENSP00000369014;Parent=transcript:ENST00000379692;protein_id=ENSP00000369014 4 ensembl_havana exon 10058 10246 . - . Parent=transcript:ENST00000379692;Name=ENSE00001784917;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001784917;rank=2;version=1 4 ensembl_havana five_prime_UTR 10246 10246 . - . Parent=transcript:ENST00000379692 4 ensembl_havana exon 36401 36926 . - . Parent=transcript:ENST00000379692;Name=ENSE00001205012;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001205012;rank=1;version=4 4 ensembl_havana five_prime_UTR 36401 36926 . - . Parent=transcript:ENST00000379692 4 ensembl_havana transcript 1944 37429 . - . ID=transcript:ENST00000515757;Parent=gene:ENSG00000173376;Name=NDNF-002;biotype=protein_coding;havana_transcript=OTTHUMT00000364461;havana_version=1;transcript_id=ENST00000515757;version=1 4 havana exon 1944 2065 . - . Parent=transcript:ENST00000515757;Name=ENSE00002059010;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002059010;rank=4;version=1 4 havana CDS 1944 2065 . - 2 ID=CDS:ENSP00000423352;Parent=transcript:ENST00000515757;protein_id=ENSP00000423352 4 havana exon 4338 4462 . - . Parent=transcript:ENST00000515757;Name=ENSE00001611953;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001611953;rank=3;version=1 4 havana CDS 4338 4462 . - 1 ID=CDS:ENSP00000423352;Parent=transcript:ENST00000515757;protein_id=ENSP00000423352 4 havana CDS 10058 10245 . - 0 ID=CDS:ENSP00000423352;Parent=transcript:ENST00000515757;protein_id=ENSP00000423352 4 havana exon 10058 10246 . - . Parent=transcript:ENST00000515757;Name=ENSE00001784917;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001784917;rank=2;version=1 4 havana five_prime_UTR 10246 10246 . - . Parent=transcript:ENST00000515757 4 havana exon 37302 37429 . - . Parent=transcript:ENST00000515757;Name=ENSE00002032155;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002032155;rank=1;version=1 4 havana five_prime_UTR 37302 37429 . - . Parent=transcript:ENST00000515757 bcftools-1.21/test/csq/ENSG00000173376/synon.txt000066400000000000000000000004131467060157400205430ustar00rootroot000000000000001944 T C synonymous|NDNF|ENST00000379692|protein_coding|-|145L|1944T>C,synonymous|NDNF|ENST00000515757|protein_coding|-|145L|1944T>C 1944 T C synonymous|NDNF|ENST00000379692|protein_coding|-|145L|1944T>C,synonymous|NDNF|ENST00000515757|protein_coding|-|145L|1944T>C bcftools-1.21/test/csq/ENSG00000173376/synon.vcf000066400000000000000000000007461467060157400205130ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 4 1944 . T C . . EXP=synonymous|NDNF|ENST00000379692|protein_coding|-|145L|1944T>C,synonymous|NDNF|ENST00000515757|protein_coding|-|145L|1944T>C;type=ENST00000379692:121958691-T-C bcftools-1.21/test/csq/ENSMUST00000121418/000077500000000000000000000000001467060157400172265ustar00rootroot00000000000000bcftools-1.21/test/csq/ENSMUST00000121418/ENSMUST00000121418.fa000066400000000000000000001111121467060157400217320ustar00rootroot00000000000000>19 19:10001570-10038380 TCAGGGAGCAAGCAGAGCACATAGGGCTGATGGGTGAAGGTTCTGGACCCAGAACATTAC AGCCTCCTCATCTAAGATCGCCATGGCAACAAGAGCATCACAGAGGGCCTGACCTTTGCC AGGCAGGTAGAAGAGGACCAGACTTGGCAGAGGGCAGTAAGCAGTAGGCCCTGGGCTGGG CCTGGCAGACCTGGCTGCTGTCTCCAGGTTCTGCATAGGGTGCCTGCTAGCCCACTCTCC TCCTCTGGGCCAATCACAGAATAAACAGGGAAGAAACCAAGAGGTGGATTAACACAGCTG GACAGGGAGGCAGAGGACATATAGTGCCACTCCAGGGACAGGAAGGAAGACAGTCAATAC CTCTTTCCTGACACGAAGCAGCTCTCATTGCTAAAGCTCTGGGAGACTGGCATAATAACC TCTGACCTTTTCAGAGGGGCAACAGGGATAAGGTGAGACAGGGAAAGGCTGGGAGACAAG TCCCAGCACCACCAAGCCATATCCCACAGATAGCAATGAAATAATACAGAATAGACCAGA ACCAACCCAGAAAGAGACACATGGTGAGAACTCAGCACAACCTGGGGGAAAGCTAGGATC TCTAGTCGTGTGGTGCTTCATGGACTCCACCCTGCAGCTACCAGCCAGGTGAGGACCTGA CCCTACCCTTACCTCTCACCAAATCCCCATCTGTTCAGTGAATTTATTTGTTTGTATGTA TGTATGTATGTATGTATGTATGTATGTATTTAGTTTTTGGTCTTATGTGTATAGGTGTTT ATCTGTATAACATATGCATGCCTGGTACCTGATGCAGCCAGAAGAGGGCACAGTATCCCT TGAGACTTGAGTTTCAGATGGTTGTGAGTCAACATGTGGGTGCTGGAGATCAAAGTCAGG TCCTCCGGAAGAAGAGCCATTGCTCTTAACTGGTGAGCCACAGTTGACTGAATTCTTGAT ACAAAGACCTACTACATAGTCCAAGTTCCTTGGGGGATATCAAGCAGCAAAAGCCTTTTT CTCTGTGGGCTCCTCAGCCTCAGTGAATTGCTTTGCCTGTCTATTTCCTCTTAGAACATG GACTCTTACACTGAGGCCCCTTAGCACGCACACACACTATACAACACACACACACACACA CTGAGGCCCCTGAGCACACACACACACACACTATACAACAGATTGTTAGAGATGCAAGGA TCTGAGGCTTCCACCCCAGACCTCCTCAGTCATAATCTGCATTTCATTTTTTTTTTTTTA GTTTTGTTTACTTATTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCTTG AATACCACAGTACACATTCGGAGGTCAGAGGACAACTTTCAGGAGTTGGTTCTCTCCTTC CAGCTTGTGGGTCTCACGAATCAAACTAAGCCTTGACCGCAAGCACTGTTATCTACATCT GAGTCAGGTGTACAACCTGGGTTGAGAGGTTGGCTTCGGGCGATGGTGAGAGAGAGAAAA GTCCATTACTGTTTTCATTTCAAAAGCACTGCGTTCTTTTGTTTGTTTGCTGTTGACACA GGCCTTGAACCTGATGTGTATCTGAAGATGACCTTGAACCCCTAATTATCCTTTGCCCGT TTCCTAAGTGTTAAGATTGCAGGCCCAACTTATGCAGTGCTGGGGATTGAACCAAGGTTT CTTGCATGCCAGGCAAGCACTCTACCAACTGAGCGACACCCAGACCTCTTTATACTTAGT TGAGAATGTTCTTGAACACATAAAACTTTAATGTTCATGAATTTTGACCTGGCTGAATCT ATTCTGAGAATTTTATGATTTTTGCTGATACAGTTAAGATCTGATATATTTTGGATTCCT TTTTGTGGAGAGTGTGAGGTAAAGGTCCAAGGCCACTGAGACATATGGGTACCCAGCTGC CCATGTGCTGTTTGTTTCCTTCATTGAATGGGTTTGGCATCATTGTTAAAGATCAATTTG TGACAGATGTATCTATTTCTGGAGAGTCTGCTCAATTCCATTGACCTCTGTGTCTGTCCT GAGGCCAATACTACACTTGTTTTGATTTGGTTTTTTTTTTGTGTGTGTATATATGTGTAA TATGTATATGAGTACATATGTGTGCATTCATATTGAAGCCCTAGGTCAATGTCAGTGTCT TCCTCAGTGGCTCTACTTCATTAATTGAGACAAGATCTCTTGCTGAACCCAGAGCTCACC AATTCTGCCTAGTCCTAGTCTAGCTTAGCCAGCTTGCCTCATAGAATGACAGGCATGCAC CAGCAGGCCCTGGTTTATACAGCGGAAGGCAGTGGGTAGGCATACTGCTTTGGAATCAGA AAGTGGGAGGTAGGCTTGGTGAGTAAGATGACCTCAATTCAATCCTCAGAATCCACAAGT GGAAGGAGAGAAGTTACTCCCACAATTTGTCCTCTGATTCTACATGTGCTCCATGGTACA TGTGCACCAATCTTCCCCTCCCCCACCCCCCACTGCATACACAAGCACACACACAAGCAA ATAAGCAAAAGTAAAACAGAAGTGTGTGTTTTTGGACTTAGGTTTTTAGGCTGTGGTTTT GGTTCATTTCTGATGCTGTGCTGAAACACCTGACAAGAGCCCTTCTGGGGAGGAGGCCTT GTCTGACTTATGATTCCAGGTCACAGTATGACCTGGAATAAAACCCATCATTTCAGGGAA GTCAAGGCAGTCAGAATTTGAAGCAGCCAGTCATATCTATAGCCAGGAGCAGAGAAAAAA AACGGATGACCATGGCAACTGCTCCGCTCTTTCTCAGCTCTTATGCAGTTCAGATTCCAA ACCCAGAAAATGAGAGCTCCCATTTTCAGCCTGGGTCTTCCCATATCAACTAATATAACC AAGAGACCCCCACAGGCATGGCCACGGATCAACCTGACACTCTCTTCCCACGTGATTCAA GACTGTGTCAAGTTGGCAATTATAGCAAACCATTGCAAGGTGCCTTGACATTCCTTATGA ATTTTAGGACCGTCTTGCCATTTCTGAAGAATGCCAGTTGCGAGTGTGACAGGCTGGTTT TGATTCCGTAGGACACCCTATCGTGTGTATGGTATCATTCTTCCTGGATGTGAATCTGTT CAATACCTTAGCTCTCTTTTAATTTCATTCTGCAAGTTTGTAGTTTTCAGTGTGCAAGGT TTTTTGTTTGTTTGCTCGTTTGCTCTTGTTGTTGATTGTTTTAAGACAGAGTCTCTCTAC ATAAACCTGCTATCCTCAAACTAGTTAGATCAGGCTGGCGCCAAACCCACAGAGATCTTG CCTGCCTTTGCCTCCCAAGTGCTGGTTATTAAAGGCCTGAAGCTCCATGCTCAATACAGT GTGTGCAAGTCTTATAGACCATCTTTGGTTAAAAATATCCTCTCTCTCTCTCTCTCCCTC TCTCTCTCTCTCTTGTGCTGCAACTAGAACTGTTTTCATTGACTTCACTTTTGGAGTCTT GATAGAAGATAGAAATGTAAGTGCTGTGTAGCCATCCTTATCTGTTGGTGTCATGTTTTT GGTGTACAAGGCCTTGTGCACACTAGCCAAACTATGCACCACTGTGCAGTATCACAAACC CTTGGTGTCATAAGACAAGGTATGTAGGCCAGGCTGGCCTTGAACTTGTGATCCTCTTCC CTTGTGCCACCACTCAAAGCAACAACTGATTTTTTTTTCTTCTTTTGCTTTCCTCCTCCC CCACCCCCTCATTAAAACAGGGTTTCTTTGTGTAGACCAGGCTGGCCTTAAACTCATAGA TTCACCTGCCTCTGCTTCTCAAGTGCTGGGATTAAAGGTGTGCAAAGACTGATTTTTGTT TGCTTGCTTGCTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGGGTTTCTCTTTTAGCTC TGGCTGTCCTGGAACTCACTCTGTAGACCAGGCTGGCCTCGAACTCAGAAATCCGACTGC CTCTGCCTCCCGAGTGCTGGGATTAAAGGCGTGCACCACCACGCCCAGCTGCTTGCTTGC TTTTATATCTGGTCACTTCACTGAATGTATCTATTAGCTATAACGGGTTTTTGGGTGTTT TTTTCCCCCCAAGACAGGGTTTCTCTGTATATCTCTGGCTGTCCTGGAACTCACTTTGTA GACCAGGCTGGCCTTGAACTCAGAAATCCACCTGCCTCTGCCTCCCAAGTGCTGGGATTA AAGGCGTGCGCCACTACCGCCCAGCTTTGGGTGCTGTTTTATTTTGTGTTACGTGAGCAT GTGCACGTGTTGCCTCCCTAAGGTCTTCCAAATGCCAAGCAGACATTCTATCACTGAGCT ACATCTCCAGTTCTTGTTGGGAGTGGGACTTGGTATTTTGAAATAGAGCCGCTGTATGTA TATGGGTTGGCCTGGGACCTGCTATATAGCCCAGGTCTAGAACTTGCAGTCTTCTCTCAC CTGCATTCCAAATGCTAGGAGTCTAGGCATGCAACACCATGCCTGTGCCCCTCTCTGATA GTACCCAGCCGACCATATTTGTTCTCGTTTTTGTTTTGATCCCTGAATTCTCTTAATAGT TGTCCTGGGGATCACCTTTACTGTCTTTATCTTTTACTTATTTCTGACTATGTAGAGCTG GCCTGGAGCTCAGAGATCCACCTGCCTTGGACTCCTGAGTGCTGAGATCAAAGGCATGCA CCACCACCCCTGGCTTAAGTTCATCTTTAGCTACTTTGGAGTTCAAAGCTACTTTGGGTT CCATAAGAACCTGCCTCAAAAAAAAATAAGTAAATGAATAAATAAAATATGAAAAAGTTT CTGACGCTAAGCTAGGGCCCATTCCTTGAACACATGAGCCTTTGGGTGGACACATCAGAG CCAAACTACAGCACATGTGTAGATAACTCAAAAGCACATACAACCACATAAAGATTTCAC CCTCTAATCAGCATTATGTGTTAAACAGGAGACTGGTTGGGAAGACGACTCAGTCAGTGA AGCACTTGCCTTGCAAGTGGAAGAACTTGAGCTGGATCCCCAGAAGCAATCCTAGAACAC ATTAGGGAGCAAGCAGTGGTGAGCACTTGTCTTCCCACTGGTTGGTGCAGAACCAGGTCT TCTGCACCTCTTTTGTGTGCTTTGAGACAATCCTATGTAGCCCACAGTCTTCTGCCATGT TTTTGTTTTGTCTTGGTTTGGTTTTACTTACTGGATTCAGTTTCCTTCATATTAGGAGGC TTTGCTCAGTTAGTTGATGATCTTCAGTTTCCTTGTGTATAGCCAAGAACTCTAGAAGCA GGGCTGGCAAGATGGCTCAGTGGGTAAAGGCACTTTCTGCCAAGCCTGATGACGTGAGTT AAATTCCTGGGACCCACATGGAAAAGAAAGAACCAACTCCCATATGTTGTCCTCCCATAT GTGTCCATGGCACACATGAATCCTCCCCAATAAATAAATGTAATATGAATTTGATTTGTT TTGATTTGTTTTATTTTCAAGGCAGAGTTTCTCTGTGTAACCCTGGCTGTCCTGGAACTC CCTCTGTAAACCAGGCTAGCCTCAAAATTAAAGATCCGCCTGCCTCTGCCTCCAGAGTGC TGGGATTAAAGATCTGCGCCACTGCTCCCAGTTATAAGAATGAGTTTAAAGTTAAATAAA AGAAAGGACTTTTAATGAGCAGAAAGAGTAGAGTGGAAACTTTAGGTCTGGCTTGGTCTA CTTAGCAAAACCCAAGACCCTGTCTCATGTCTCAGAAATAAAACAAGATGGAAGCTGGGC ACGATGATGCACTTGGGAGGTAAAAGCAGGAAGTTTAGGAATCCAAGGTCTTTGGCTCCA TAGTGAATTTGAGGTCAGCATGGGCTACATGAGAGCTCATCTCAAAACAAAAGAAAACAT GGATGGGATGCTGCTAAGAGTGATGGTCAAGTTTCCTTTACCTACACTTTCCTTAGCTGG ACAGTTACAGTAGTCTTAGACCTATTTCTCAGGCTGGCCAGAATCCCAAAGCCAGATGTG TGGAGAGTAAAGGTCTGACTGTCAAGAGGCACGCGCGCGCACGCGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTATGTGTGTTGGGGGTTGGATCTCAGTGTTCAGCATTTGCAAT TTCTAAACTCCCTCAGGCAGCTGCTACTGATCCAAAGAACCTTCAATTTACCATCTCCAG AGAGTAATTTCTAGTTTTAGGTAGGATTCAGAAAGGTGAACTGCCTGGTGGTACGATGGG AACAGACCCAGGGATGCAATTGCTTCCCAGTTTGTTTGGAACCAGTGCTCTACGCTTTAC TGCCAATGCAGAGGTCTGCTACTGCCAAATCCAATGTTCTGCTTCCCGGTTCTATCTATT AGTCTCATCCCCCTGATGGCAGCTTTTATCTAGCTGCTCCTTGCAGCTCTTACAGCTCTT GCTTTAAATATTTCATTAGGTATCTATTAATTTAGAACTATATTATTTATCCAATGAATT TAACTTCTATTTTTATTTTTTAAATTTTTACATGTATATGATATATAATATATATCATGT ATATAACGAATTTCAGCCCGTTTCACCTCATTCACCTCTTTCATGCCCCTCCTCTCTTCT TCTCAGCAAGTTGCTATGCAACTTCCATGTCTTCTTTTTTATGTGTGACCCACTGTGTAT AGTTCGGGTTGCTTGCACGAGCACTGGTGGGCAGTTATTTACTGGACTAAGAGCTACTTA TCAGTGCCTACACTACTGAAGAAAATCATTTCCTTCTCCCCCAGCAAGTCTCAGCTGCCA GTAGCCCAGCAGGGACAGGTGGGACCTCATAAGTACTTCCACCGTCCAAGATGAAGTGTT GAAGGGCCTGCTCCTGGGTAGTTGATGGGCACAACAACCGTGTCATGTCCAGAAGACAGA GGTTCACATCACTCCTCCCTCGCTCCCCCTGGCCCTTACATTTGTATGTATCCTCCAGAG ATTCAGTTCTCTCTCTTGCTGGGTCTAATTTGTTATGTAACCCCTTAGTTTGAAAACATA TTCATTTGGCCATTGAATTTTTTTTTCTGTTCTCCTTAATGATCTCATGCTGCTTATTAA CCTTAAACTTCCTGCTTTGCATAAAGGAGTCTACTATCTGGAGCCCTAGGATGGTCAAAT CTATTTGTAGGTTGTAGGTTACTTCTTTGGAATCTCACTCATTGTAACTAGCATTTTTTT TTTTTTTGTGCTGGTGATCTCTGATTGACAGCTCCTTGGTCAATGTTGACTAGTGGGAGT CCTGCAGGAATAGAGTCAGATACTTTCCTCCATAGACTCACACAGTTCTGTCATAGGATG TCACCAACATAAATATTTTGGCTTTCCTAGGTTCATGTAGTTGCTCCACAGTCAGCCCCC ACCCTCTCTGCTGGTCGTCCTGCTTTGTCCTTAATCTCCTTTGTAAGGAAAGAGATCTTG GCAGCCAACAAGGCCTCAAAGAATCATGGCGTCTCCCTAGGATTTGTTTGTATAGAGTCA CATTATGTTGCCCAAGCTGCTCTTCAATGCTGGACTTAAGTCATCCTCTTGTCTCAAGTA GTTGGAATCACAGATGAACCCTCCCATGCCTGGCTTAGGGTATTCATTTTCAGTAACAGA AGGGTTCCTCATTGCTTCAAGTCCAGCACATCGTGAGGAGCAGAAATGCCCCCGTGTCTA AATGCACCTAGGAGTCTTCCTGGGTTTTGAGACTATTTTATGAAGCTCGGGCTGACCTTA GGCTCACTATAAGCCAAAGCTAATCTTGAAGACCTCCTGATCTTCCTGCCGCTACCTCCC AAGTGCTGGGATTACAGGACTACTTCACCGTACTTGGCCCTTAGAACCACCCCTTTGACA TGGAAATTCAGTCACATCAGCCATCTGCTCATGACTTCCTTGTCCTTATATGCAGACTCT AGACTCAGGATTCAAAGCTTCCTGCCACCCCCATGATCTGGTCCCTAATTCTCACTTTAG CCCACATCTTTCAATGATTCCCTTCTCTCTCCCACCCGCTCGCCTAGGATCATAGGTCCA GGCTACGAATTGCTGGGTGAGTTTCCAGAGTATCCCATACTTCCCTTATTTGGGTGCCTT CCACTCAGTGTCAGATTCCGCTGTCTGAATCTCATCCCCTACACACCACCACCTCCCAAG CTGAACTTCATGAATGGAGAGATAATGCCTTGATCATTGACATTCCACACCCCCCATATC AAGTGCAATTAAATGGCCAAATGGGTATCTGCTGGGCTCCCAGTGTTCTCTTGTTAATTC TTATGAATTCTTGATATGTTAAAGATGTGGCCCCTTTGCCATTGGCTGAGCATGCTCTTC TAGATTATTTGCCTTATAATTTTTGCCATGGGTGATGAGGGTAAGGGAGAGGGCTTGGAA AAGTTTTCAGTGTTTACATAAACAGATTGGTTGATTATCTTCCGTTTCTATCCTGGCCAG TGCTTCAAGACTGGCCAAGTCATCCTCCCTGGAGATTTGATGAGTATTTTCAGCTGCCAG CCCTACTCCGCTCACCTTGCTAATAGAATGAATGAATGAGTGGATAAATGGATGGATGAA GGAATGAAACAAATGTTAACAATGCTCCTAGAGCATTTAGAATGAACTCCACATTGTCTA GCTTGGTCTCTGAGACTCCAAGCCTTGAGCTCTCTTCCCAGCCCTTTCTGCCTTTTCTGG ATGATGCCCTATTCATCCCCAAGCTCCCAGGAGGTTGAAGGATCTGCCTCTCTCTGGACG TGTCTGCTTTGGCCACTCCCAAGCCTGCTGCTCCCGCTCCCTAAAATGCCCCACTTCTAC TTTAACTATTGCAAATTTCTCAAGTTCCACTGATTCCAAAAGCCCTCGTTTTCAGTGCTT GGGAGCCAGAGTCAGGAGTGTTGCCCTGAGGTCCAGGCCAGCCAGGTTTCATAGTGAGAC CCTGTTACAGAAAAACAAGAAATTTGGGTGGATGAGATGGCTTGGTGGGTTAAGGGTGCT TGCTGATAAGCCTGACAACCTTAGTTCAATCCCTGGGGCCCTCAGGTGGAAGAGGAGAGC CGAGTTTTGCAAGTAGTTCTGACACATGGCCTCTGCATGCCCCTTCCAAACTAAATAATG TGAGAACAAAGCAAAACCAGACAGGGCTCACCCAACATCCATGAATCCCTAAATTAAATT CTCAGCACACACAAACTGGATTTGGTGGCACGTGCCTGCTGCGACCCCAGCACTGCAGGA ATTCAAGGTCATCCTCAACTACCTAGCTAGTTGGAGGCTAGCCTAGGCTCCGTAAGACTT CTTTAAAAAGCACACAAACCTCACTGATCCCTCTTTTTGGAAGGTGAGCAGGGGAAAGAT GAGAAAGTGATATTGGAAGTCAGACCCAAGTGTCTCCACTCATTTGCTATTGGCCATATC CTTTAGGCTCCCCGGTATCTTCATCCCAACCTCCTTCTCCTGTAAAAGATGAAACCTGGG TCTTATGCTTGCTAGGCAGGTGCTATGCCACAGGCCTAAGCCCCTAGACCCCAGTTCCCC TCTTTAAGACCTTAGTCAGGTGTGATGGTACACACCTTTAATCCCAGCATTAAGGAGGCA GAGGTGTGTGGATATCTGTGAGTTTGAGGCCAGTTTAATCCATAGAGTGAGTTCTAGGAT AGCTAGGGCTACATAGAGAAACCCTGTCTTGAAAAACAAAAATAAGCCGGGCAGTGGTGG CTCACACCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGCGAATTTCTGAGTTGGAGGC CAGCCTGGTCTACAGAGTGAGTTCCAGGACAGTCAAGACTACACAGAGAAACCCTGTCTC AAAAAACAAACAAACAAACAAACAAACAAAAACAAAAAAAGAAAAGAAAAACAAAAATAA AATAAAAATAGGAACAGAAGGTAACAAGGACCATATAAATGGGTGTGGCATCCTATGTTA GCAGGTCAGAGCTGAGCCCCACATTCCTTCATATGGACTCTTCCACTACAGTCATATTTT CTCATACTTGTGTTGGTCCCTGAAGGTCTGAATGGCTCTCAAACTCATCAGGTGGCTGAG CTTTCCCGCTGGGCAGATTTGAGTGACCAAACAGGTTTCCTCTCTCCAAACCAGCCCAGG GGCACCTAGATACATTTTCACACACCTATTTGGCCTAAAATAATAATCCCCCCCTCTCTC TGCCTGAGCTACAGTGGCTTCTTCAGTCTCTAAATTTAATTTCCAAAGAAGTTCACCAAC ACCCAATGCCCCCCAGACATCAGCAACCCCAATACAATGAGGAACTAGATAAGCAGTTCT CAATCTGTGGGTTGAGACCCCACAGAGGTAGACTATCAGATATCCTGTATAGCAGATATT TACATTATGACTCATTATAGTAGCAAAATTATAGTTATAAAGTAGCAATGAAATAATTTT ATGGTTGGGGGTCACCCCACCATGAGGAACTGTATTAAAGTGTCACAGCATTAGGAACTT GGAGAACCACTGACTTAAATGAAAGGTAACCCTACTCCATTTTAACATGGGTAAACTGAG TCTCAAACAACCATCGCTGGGCTGGAGAGATGGCTCAGCGGTTGAGAGCACTGATTGTTC TCCCAGAGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCCGCAAT GAGATCTGATGCCTGCCCTCTTCTGGTGTGTCTGGAGACAGCTACAGTGTGCTCACATAC ATAAAATAAATAAATGATTCTTTAAAAAAAAAAAAAAACAACCATTGCTATAGTTGGGTC TGGAGCTTATGTGCTTTCAAAGCCAGAGAAAAGAATCTTCTCTTGAGGTCCTGAGGGTGG GGAGTACTCGGGAGGGGACACAGCCTGAACCACAGAGTAGTAGATAGGAGGGGGTGTCCT GACTCTCCAAGCCTCTCTCTGAGTCTATAAAGCAGCTGGTGGCACACTCTCAGAGGCCAC TCTGGCCCTCTATTGTTTTGTGACCATATACAGATCACCATATACCAAAGGCTATCTCGA CTGAGTCTTTTGAGGAAGAGCAAAGATAATGTGACTCCAAGGCTGAGGGTAAGGACTCCC TGGAGCACAAGAAGTGTGAGTTTAGCATCCGGAGATCTGGTTTATTTTTAAGTTTAAGTC AGCATGCTGTGTCCATTTAGACAAACACACCTGCCCCTAGCACCCCAACTGTCCTAGCAA TAAAATGGAGTCTGTGGGACAGAAAGATCTATGCTAGCATGATCTTCACATTCTTAGAAT TCTCCAAGAGCTGTTCCTCACCCAGCCCTGCCTGAGCCCAGACTGTCCCCAGGGTCTGAC TTCATCATTGGCCTGACTAAGTGTTTGACACCATACAGCTGCCCCCACCAGCCATCCAGC CTTTCTGTAGAATCCTGGCCAGACTTCAGAGCCCCATGGAACAGGAGCTGCGGGCAATCT TCTCTGTCAGGCCCGGGGGACACAGGGAGTGGGGTATCCAGGCCCGTGTTTGAACGTCCC AGTCTCTTCCCTTTCCCTCCCTGGAGCCAGCATCTCCCTCCCTGGTGAAATCTGAGCTCA GGGATCCAGGGAGAATTCTGGCAGCAGAACATTCCATCCAGTTGTCCAAACACTGCACAG CTGGCGGAGGGAGGGGCAGCCAGAGGAGCGGGTCAGGAGCCCAGAGGTTGTGTTGTTTTC TTGGAAATGAGGGAGACCTTGCTGGGGGAGTAGGTGGGTTTTTAAACCCTGGCTGCCTGG AAAGGATCATAGGACAAGGAGGACAAAGTAGTCCCCTTTGCTCACATTGTCTGGGGCCTG CTTGCTCAAGGTCATCCTGTGGAGCGCCTGCAAAAGTAGATTCATCTACCTCAGAGCCTG CCCAGCCAGGTCTGGGCAGCTACCTCTCGCCTTGGGAGTCTCCTCCTCGTGACAAGACTC CAGGCTCAACCTCAAGCAATGGGGGGAGGGCAGGCAGGGATGAGTATGAATAGCAAGCCC CAAGAGAGACACTAGACAACAGCTCTGTTGCCAGCTGTCTCACTCCCAACTGTCTCCCAG TGCCCTCATCAGTGACCCTGAATGACTCTTCAAGCCTCAGTTTCCTGATTTGCAAGAGAC CAGGGTTGACCCCTTATTGCCTAGCAAAGGTCTTCACAGATCTTCCCTTCTAAGCAAATG CCCAGAAAGTAGCTCAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTTTCTCAGCACTTGTGACTCAGTTTCCCCACTGAGCACCCCCCAATGCCTTTTAC TACCCTCCAGGTCTGGTTGCGTCAGGGTGGTAGGAGATACACTCCCTTTCTGCACATCCT GTTTTCTGCTAATGGTTTCCAGGTGAGCCCTTGGTTGCCCTGCAGAGGAAGGTGGGGGCA CTAGAGAATTTAGTAGGGGATGATCGAGGAGCAAAAACAGGAAGGGGGTGGGAGCAGGCC ATGGAAAATTCACAGCCAGGAAACCCTCTGACAGCATCTGGCTTGCATTAGGCTAAGCAG GCTTCACAGCCTGGAGCTCAGCAGAGATACTGTTATCCGCTGGCCTGGCCGGCGGGCTGG GAGGGGTGTGGTGCTGGTGGGGAGGGGCTCAGAAGGACCCAAAGGCTGACCAGAAACAAT AGTGAAAGTAGAGGAGGAGAAGGAGGTTAGGAGGTGACATCAGGGCAGACAGACCTTCCG TGAAGGTTGCTGTCTTCCATAAGGGAGAATAGTTCCTATTTTATAGATGAGGGCCCCAGA GAGGTTAAGTGACTTGTCCAAGGTCACACAGCCAAGGAGGAAATCTTTTCTTTTTTGAAG GCACAAAATGGGATAGAAGTTGAAGTTAGTGTGAGAATTGGGTGTGTGGTGACTCAGTAG TTATCTATCTTGCATACACAAGGCTCTGGCTTCAATCCCCCTCGCTACTACAACTACCCT GCTCAGGAAAAAAGAAAATGTGGGGAACAATGTTTGGAAAGAAAAGGCAATTTGAGGTGT ACCTGGGTGGTGACAGTTAGATGTGCTTCAGAGGCTAAGAATCCATTTTATGGTTGGGGA AACTGAGGCACAGAATGGCTGAAGTGATGTTGAATTGTCCTTTGGTGATAGTAGTTGATG GGCTTAAGGGACTAGCTACTGAGTATCTGTACAAAAGCAAATAACCAGCTTACAACTAGG CTGGACAGGCCTAGTGTTTCATCCTAAGACTACCAGAGATAGGCAGTCTCTCCAGCGATC TTGTTGAAGCTCAGGGCATCGGCATGTGCGGTAGCTTCTCTCCTGTTCTCAGGTATATCT TGTCCAGCTCATAGCCCACAGCCCAGGAAGGAGGCCCATGTCTTCCGCAGCCCGCTGAGC CTCAGGAGTTAATAATTAAGGGTTTAAGAAGATAGAAGCCTGTCTGGGAGGCCCCGCCCG GCCGCTGTGCTCCTGCTCCTGAGAGATAGCAAAGGTTAGTGTGTGAGGCTCTGCCTGGTG TGGAGGCAGGCTCTGCGCTCGACCTCCTGGTGGTCTCCAAAGGGACCTCAGCCTGGCCCC AGGCATGGACGCCTCTGAGGAGCCCAGGAAGTGCCCTGCCCGAGGGTCATGCCCAGTGTT CTTGGCCATGAGCTCAGGCACTGTCCGCTATGCTCCATCAGGTGTGGGTCCTGTACCTGA GAGGAACTTTAGAGAGGAGACCTGGGATGCACACAGGTGAGCTGAGGTCGTGGGACACTG AGGGGAGGTGGGGGATGAGTCTTGACACTCTGCAGGGACATGGGGGTCAGAAGCTGGCTT GGAACAAGGGGTGGTTTTGAGTTGGGAAGAAATTCAGGAAGCTTCTCACAAGTGGGCACT CAGAAAGGAACCCTGATTGTCTGGTCCAACTTGAGGTCTTGACTAAGGTAGAAACTGAAG GTCAGAGACAGCAGGCCACTCAATCCTAGGCCACAGCTAGAAACAGATGTAACTTCAGAA TCTGAGACTGGTTCAGATTCAAGTCCCATATGCCTTCAGCCTCATCCTAGTGTCTGTGAC TAACGGTAGCGAGCTGGGGGAGGGGAGGGTTGACAGGAGGCGGTGGTGTGGAAGGAAGGA CGATGAGGCTTTTGGTGATCAGTAACTATAAATATATCTTTAATTTTTTTCCTCCCTACT GGCTGGGCCTGGCACCTTGTAGGTATTCAGTAACCTTCTGAGGGCTGGCTGTACCCAGAC ATAGCTTCCACCAGCACCAGTGGCTCTGGGTTGTCCCTAGGGAAAGCTTCTGTAAAGAGA TTCCACCTCCCCTCCCCTGGCTCCTGTGACATAAGGCAGGTTCTTTAACTTCTCTGAGGC CATCCCCTTCCAGTGGCCCAGCAGGGCTCCCTGTGCTGCTGAGAGGAAGCCCAGAGCTTG GAAGTTCACAGAGTCTAGATGCACAAATGACAAGATATTTTTGGTTAGTAATTGCACGTC AATGGTCAATGCTCTTAGGGTGGCAACCACACACTTGTCCTTGGAGGCCTCAAGGGCTCC TAGGATGAGGCCTCTTCCCCGGGAACCTTCCCCTTTGCTGACACATCCTCTTTGTCTCTC ACTAATTCCATTGACAGAATTTATCTTTGCCCTGGCTTTTAAACACTCGGAAGGCAAAGG CCCTGTCCTGGACTCTTTTTGTGTCGTCTTTTCCTCCTTCCCCTAGATGGTGACCAGAGC AAGGAACAGGAAAAGAGCATTTGCTTCAGGCTTAGGTGAAGGGCTCAAGTCAACACAAAT ATGTTGATATCTGCTTTGGCCAGACCCTAAGCTGGGCTGGATTGGGTGGAGGAACATAGC CCAAGGGTTGGTCCTTGCTCAGGAGAAGCCTGGTAAATATCACCCTATAGTGAGGGAAGG ACGTAGAAGACCTGGGCTGAGAGATTCTGTCAGATGAAAAGGATGCTATGGAGAGCTGTC TAGGTTCTCCATGGAGAAGATGCCAACCATGGGCAAAGACGTGGATTCCACTCACCAAGT CTTTGTTCCTATAAGCTGAGATAGGAGCATCTTGTCTTTCTTTAGAATACTTTATTACGT GTGTATGTTCATTTGTGGATTTCTACACACTCATGCAGGTGCCCACAGAGGCCAAAAGAG GGAAGAAGAGGGCATAGGATTCCCCTGTAGCTGGAGTCAGAGTTTTGAATTGCCTGATAT GGGTGCTGGGAACCACACGTGGGTCCTCTGTAAGTGCAATGCATACCCTTTCTGGCTGAG CCATCTCCAGCCTAACTCTTTTTCTGTGTTGTGTTGTGTTGTGTTGTTTGGGGGGGGGGG TTCTTTTGTTGTTGCAGGGTTTTATTTTGGTTTGTTTTTTTGGCTTTTTGAGACAGAGTT TTTCTGTGTAACAGTCCTAGCTGTCCTGGAACTCACATTGTAGAGCAGGCTGGCCTTGAA CTCAGAGATCTTGCCTGTCTTTGCCTCCAGAATGCTGGGATTAAAGGTGTGTGCCACCAC ACCCTGGCTTTTCTGTTTTGAAAAGAGCCACTATTAGTTGGTGAAGATGGGTCCTAGGCA AGTCAAGGTTCTGGCAGTAGAGGTCCTTTAAAGCAGGTCTCCCATTCTCCTACCATTTAC CATACTGGAATTCCATAAGCCAAGCGTGTGGTCGTAGTCACTGAGGGAGCTGAGGAGAAA GTATTAGTTCAGCCCAGAAGCTGGAGACCAATCTAGGTGGTACATGACCAACACCCTCAG AGAAGAGGGGGCTAAGGGAAAGGAGAGAGGGAGGCTGGGGTTCCAGCCTGGAGAATTTCT TCGTTTCACGTGGTCCTTAGCAGTTCAGAAGGGGCGGCTGTTGTGTAGATGGATGAGTGA AATGTGTTCTTACAAGCCCAGGGAGCACTGTAGACGCTGCCTGTGGGAGCTGGTCTAGCA GTACTCAAGGAGAGGTTGACTATGGGCTCTACTTATTGGATCCTGATCTGAGGCTGAACT TCATTCAGGTCAGTGGTTAGAGCCAGGATAAAAGGAGGGCATAGGAACTGAGGGACAGGT GACTAAGCTTTTTACAAATCTTTTTTTAAGTACCTGGGACAGACAGGTGCTAGCGAAGTT GGCAGAGACGTCTCCTGTGCTTAGGATGGCTTGAAAGGCAGGGACGAACAGAGTATTCAG AGATGCAAGAGGAGGGACCTGGAAGTAGAGCTGGTAAGATTGGGCCAAGGTAGCGCTCTC TTAGCTTAAACTGCTCAACGAATGATAACTTGTTCAGGGTCTGCCCCGCCCCCTTCCCAG AAGCCCAGTGTCAATCAGGGATTGATGCCATCTAAGAGCTCCAGAGACCGGTAACAGGGC TAGAAGTCTGAATGAGGGTACAGGAGCTGTTTGTCCACTTTGAGTGACAATCTGAGCGAG AAACAGAGCTGAGACCACCCCCGAGAGCCATTGTAGGTTCTCAAACAAGGGTGGACCAAA AGTGCAAGGCAGAAAGTGATAGGGAAAGGCGGAGGCCAGCTCTGGATGCAAGATGATGGA ACCAGTCCCGTTCACTCTGGCGGGTCATTGTCCCCAGGCAGCAAGAGGGACAGGGCTGGG CCGGCAAAGGGGCGGGACCGGGCACGTGGCCTGGGGCCCGCCTCTCAGACACGTGACCCG CCCAGGGCAGGGGAAGGGCTCCGGTGGGGCGGAGCCGCAAACCCAGGGCGGCCAGCGGGA CAGACTGGCGGTGGAGCGATTGACAGGCGGCAGGGCAGCTCTGGGGCCCCCGGCAGAGTT GGCGGCGCGCGAGGACGCGGCTACGGCGGAGACGCTGGGATGTGGAGCGGGTAGGTCCCT GCACGCCGGTGGCTCTGCGCTCCGTCTGGGCCGTGCTGGCCTCCTGGGATGGGTGAACAG GGGCTCACTGCTGTTGTTTGCACCCCACTTGGGAGATAATCTGTACTCTCAGCCCTGCCT GCAGCAGCGAGGTGCATTGTAGCATGAGGACACACTGCAGCCCGAGAGCTGAAAGGACCT TGGCAGGACCGATCTGAGTTGCCCCAGGGTGAGAAGGGTGACCCCCTCCAACTCCTAGCT CCAGTGGAGTGCATGAGAGAAGTGGTAGTGGGGGTGGTGCATAGTAGTATGCATACCTCA AAAGTAAATCTGGGGCACGTATTTAAAGGAGAGCACACCCATGAACTCTGGAGAAGCAGT GCAGTTGAGAAAGCTAGCTGTGTCTCTCCAAGGTCCATCCCTAGCTAGTTGACTAGAACC TTCTGATTCAAGATGTGAGGTGGGTGGTACCTTCCCACAGTCTGGAGGGAGATAGGCACA GACCCTGAGTCCTGGGTGAACCCCTTTCCCACCCCTCATCCTCACTTCCATCTGTTAGGG CCATCGGTTCTTGAAGCTGACTCCTGTTCTTGGCCAGTCTAATAGGAGGAGACCTTGCTC CCTGTTCACATAGGTTGATGTTCTTTCTTGTCTAAATAGACAAACGCCTCCTCCTTCCAG GACTGCAAAGACTAGGTCTTGCGGTTGTTCCTGCTAAGGACTGTTTCAGGATAGGCAGAG GATAGGCGGAAGGAGGAGAGCCCTGGGGAGGGGAACAGGTGAGATCTATTTACTCTCACG GACCCCAGCTGATTGGAGTCGAAATGCTAGGGGAACCATGCAGCTTCGACACGGCCAGGG CACTAGAACTGAGCTCCTGTGGGGTGTGGGCTGGCTTGATCTTTTAGAGGGAGCAGAAGT CAGCCTGTGTTTCTTGGAGAGTTGCTCCAGGGAAGGAGGCTAGCTAGGCTTGGGAAGTGT TTTGGGTGGGTTCCTGGTGCCTGCCTCTGGTGGAGGCAATTGTGCTTGGAGGAATGCATG TGCCTGGGGCTGTGTGTTTGAGGAGCAGCCTGGTCTGAAGGAAGCTGTGAGCCTTTCTGC TGGGTGGACCGAGACAATTGCTGTATGGCCCTCAGGGTAACAACACCCCCTTCTCTGGGT TGGAGCCAGCTTGAGCACTTTGGGGGAGGAGGAGGGTCAGAGGAGATGTCAGGTGTCCTG TCTCTCTCTGTATTCCCAGGTCTCTCACTGAACCTGGAACTTGTTGAGCCAAGCTGGTGG CGAGTATATGCCAGTGATTCTCACGGTGCTGTGTCCCCTCGCAGTGCTGAGCTTGCTGGT GCATATGATGACCACACTGGGATCTGAACTTGGGTCCTCAGGCTTACACAGAGAGCCTTC TTACCCACTGAGCCGTCTTCCCAGCCCTTGGACATAGGGATCCGAGTCTGAGTGTCTAGA ATGTTCTGGGGACTTAGGGGCCTTGGAGCACTCCACTCCCTGCAGAAGGTGAGAGGGACC ATGCTCCGGGTCATGTCAGCTCTAAGAGGTATATCCTAGGAGGTATGTATCCTAGCCCAG GAAAGCTTGGAGCCCGGCCATTCTGGGGTTTCTGGAGGTTGGCTTCCTACTGTAAATTGA ACTGAGCTATGGTGTTTTGTTTATGGCAGAGTCCTAAATGGCGATAAGCAGAAGTGACTG GGCCCTGTAGGAGCCAGGAGTAGAGATCCTTCTGAGGGTAAACCTTGAACTCTGAATTAA TGGCAACACGAGTCTGATTTTTGGAGTAGGGGAAGTGGGTACAGGGTCTCATGTAGCCTA GGTTGGCCTCAAACTCCCCATTTAGCCAAGGATGAGTCCCTCTCTCCATCTCCCAAGTAC TGGCACGACAGGCATGTGCCACAATGCCTGGCTTAGGAGTGCTGAGAATGGAATCTAGAG CTTTGTGCTCTGCGCAAGGACTCGGGCAGCGGGGCTGTGTAACCAACCTTAGCGTCATTT TGGTTTGCTTTATTTTGGACACAGGTTCTTACCATATAGATTAGGCTGACCTGGAATTCT TTTTTTTTTTTTTTTTAAAGATTTATTTATTTATTATATGTAAGTACACTGTAGCTATCT TCAGACACTCCAGAAGAGGGAGTCAGATCTCATTACAGATGGTTGTGAGCCACCATGTGG TTGCTGGGATTTGAACTCTGGACCTTCAGAAGAGCAGTCGGGTGCTCTTAACCACTAAGC CATCTCGCCAGCCCCTGGAATTCTTTTTAAAGAAATTTTTATTAGTATGGTGTGTGTGTG TGTGTGTGTGTGTGTGTGTGTAAGTTGAGGGGAGAGAGCACATGTGTCATCACACACATG TTGAAGTCAGAGGACAACTTTGTGCAGTTGGTACTCTCCTACTACTTTTTATGTGGGTTT TAGGGATCAAAATGAGGCCCCCGAGCTTATACAGCAAACCCCTTTCCTCGCTTAGCCATC TCACTGGTCCTCACCTAGAATTTTTAATCCTCTTGGCTTAGCCTCCTGGATGCTGCACTG CTATGCCTAGCTATCTAACCTCACTTTCAGGGGCTCCACTGCCCCAAACAGACAGACAGA CAGACTGGGCTTCCCCTCCACCATTTCTTACAGTTTCATAGGCCTGTGGTCTTGGGGGCC AAGCCCACTCTAGGTGATGGAGTGAGGATGATATTTTGAGAATTCTGAACCTAACACAGT CCTGGGAACATTATGGTTCGTTGGCAGAGTCCAGAGACTGAGTTCTGCACTGGTTCTGTC CCACTGGGCAGCCACACGACATTGGTGTGACCAGCTGGTCTCAGTTTCTCCACTTCCTGG ATAGGACAAATCATACATATCTCTAGGGAGACCCAAATTCTAATGGAGATCACCCTGCCT CCCAGGAGTTAAAGGCCATGCCTTTACCCCTGGCCAGCGACTAGGGAGTTCCACAGTTGC AGGTGTCTGGGCTCTGCAGTCTTGAGCAAGTCACTTACCTGTTTTGGGCCTTCACTGCCC CAAGAGCTTCTGCCATGAGACCTAAGTCAGGGGACTGAGGGCCCCAGGATCAGGCAGATG CTCTCCCCACTCAACCCTGGCCCTTCAACAGATGGAAGTATCTTGCCTTCTCTTCCTTAC CCTGTACTTTTGTGTGTAGGATCTGACCAGATACCCTCAGTAGAGCCCTGCCTCTCCAGG CCTGGGAACTGGATGTATCCTCGGAAAACCTTGGGAAATGAGGAGGGGAGGGTACAAAGC AAAATAGATGGTGAGGAGGGGATGCCATGGTGGCTCCTGAAATCTTCCTTGCACCTATGG AAGGATCAGGGTGTGGAAGCTGGCCAAGTAGGTGTTCACTAGGTGCATGCTATAAATGTC AAAGGTGTGTGTGTGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA GAGAGAGATGATATCTTGGACTAAATGTATAGGGAGCCCCTCAAAAGCCTGTACCAGTAG AGCATACGATTCTCTCTTATCTAGGCCTGGTTAGTGGAGAGACAGAAGGCTGTGTCCCCT CCTAGACTGAGCTAGTTTGGCCTGGGGTGGGGGCAGTGGCAGTGGCAGTGGCAGGAAGAA TCTGGCCTGGCCACCTACTTAGTCTCTTGATCTCTTCCTCCTACTAGGCCCTGCTGCTGC TCTTGCAACCCCACCCCCATGTGCCAACTCCCCTCTGTCACAGTGGCTTAGGCCCATCTT CTTCCTGCCCTTTGTGTCTCTTTGCCTTGACTCATTGGGTTCTGACCCAACTCTTGAACC TACTACCAAAGAGATGAGATGTGTCTCTGATCTCAGGGTCCCCCTCTGCCACCCACCCCT AAGCCCAGGCTCAATTCTGGCTGTTCCCAATGATGCCTCCCAACAGCTGCTACGGTCCTG CCTTTTCCCTTTAACCACCCACAGCACTCTACTTCCCAAAAGCCTGAGCTACCCCCTTTC GCTTCCTGGAAGACCCCTTCCCACTTCCTCATTCCCATCCCACAATTCTCATTCACCTTT CCCTCGGTTTTAAATTAGCTTAGTTAATCAATTACCGTACTGCATATTTTACCTTCTCTT CTACCCAACTCCCGCTCCACTCCTACCCATGCTCATGGACCCCCTACAGTGTGTTGTCTG CCTGTGTGTCCTCCCTCAGCTAAGTCCTGCCCAGCAGGCAAGGAAGCCCTGGGCATCACC CTTCACCACTCCTCCCTTACTTGGGCACTGTCTCCAACTTCCTCAAACCCCATGTGCATC CTGCCTCACTTCTCTGAAACCTCCATTCATTCCCGCTTCTGGGGGGCAAGTCACATGCTG TTTGTGCTGTGCCTGCAGTCTGGGGGCGGGGGTGGTGTCAGTTCTAGTCCTGTCACCTCC TTGCTTTGTATACTAACCCTGCCTCATTCTGGGATGCCCATCTCACTGTGTGACTGTCAT GACACCCATGGTGTTGGAAGTGGTGGGTGAGCTGGCCTGAACTTGAACCAGGAGCCTGGA ACCCCTGTGCACATGCTGGCTTGCTGGCATGTGGGCTGCTTATAGAGAACCATTACAAAA CCTTTGCTGGTACCTTGTTGCCACCTGAGAATCGAGTCATATGTCTGTCATTCTTACTTA GTCTCCTAAATGGGTCTGAATCCACTCCCTGCACCATAGCACTGCCCTTCTGAGAGAGAG TGAGTTCCAGGCAAGATTTCTGAAGCTTCCCCAGGCACCAGAGGCTCCCAGCCAGTCCTT TCCCTGCTCCAGAGCTGTGCTCAGGGCCCCCTCTGCTGTTTATTTAGTGAACCATTGTGG CAAGAGAGAAGGGATTAACTGTAGAAAGTAGAGGTAGAGGGCCATGCCTGCTTGCTGAGG AGCCCAGAGCAGGCTGGCTTGCCAGACTGGGAAGCTCAGAGGGTCTAGAGAGACCCCTAT TTAGCTCTGGCCAGGAATTCCTGATGAGAGGGGTTTTGAGCATCTGAGTGGCCGACAGGC CACAGGGTTCAGGATTGCTCCTTTAGTTATGCTTTGAGAGGTAGAGACAAACATTCCTGC TGCCTCTACAGGACGGGCTGGTGGACTGCGGATTGCAGCCACTGCACTATGCTTCCTGGG GAAGTAACCCAGGAGAGGGCTTCCTGTACGTGGGGGCCCTTGGCTCCTAAGCTAGCTTCA GGATGGGGGATGTTGGCCACGCCATCTGCTTCTGACCTTGACTCTTAATATCTCTCACCC CTAGACGATTGGTTCCCATCCCATAGTATGCTCCTCACAAAAGATTATATTCCCACAGCA TCTGCACTGAGGAGGTGCAGGGATCTCAGGTTCCTACTTGGTGGAGACCCGAAGAAGAAG GGTTCACGGGCATATTTTCAGGCTGAAGTGTGTGGACGGTCAGAGAGTCTGGCTCTGTTG GACCCAGGGAACCCTTTCCTTCTTCTCTGATTCTTTATGAATCACCAGAACTGCCCTCAA AGGGAAGAGGATCTGCCGACTAGAGTTGTTGCTAAACACACACACAGTTCTACCCTTCTT CCCCTCCTGCCTCTGTATCCCTTGCCAGGACACAAGCGCCTGCCTGTAGGTTCAACTTCA GGACCCAGAGTCAGGGCGAGCATTTTGGGCGTCTCTGCCCAGTCAGAGTTGATCTCTATT CACCCAGCACTGTAGCAAGTGAGTTCCTATTTGGTTTTGATAACCTCCCTCTGCCTCATG GTTTCTTTATCTATCTATGGGGAGAACAGATTGCAGGAGCTTCAGGCATTCCCAAGACAA AGCATGGCCATGATCTTGGCCACAGTGCCCTCCTCCCCCCCCCCTCACCCCACCAGGCAA TCTAGGCAGGGTGTTTTCTGGCTTAGCAAGAGTCCAATTTGAGCTGGACTGGGTAAGGCT TCTCTGCTGTAACTCATAGCTATGGAGCTGCCCTGGGCCCAGAAACCCTTGATCATCAAG CATATGTGCTGATTCCAATACTCACCCCATACCAGGCCACTTGACCAGTAGCGGGTGGCG GGTGGGGGCTGAAGACCTGGCTGCCTGTCTCCACACTACCCCTGACCAGTTATGGGAACT CCATGGAAGTCCCCTCCTCTCTCTGGGCTTGCACCCCTATCTGTAGTATGGGGGAAAGAC TACAATTACTGTGTAAAGAATATATATATATTATATATATAATATGTGGGGCTGGGGGAG GGAGAGCACGCTCAGTCATTAAGAGCACTTACTGCTCTATCAGAGGACCCAAGTTCCCAG CACCCACTGCTTGATGCTCTACCACCAGGGGATCTAATACTTACTTCTGGTCCCTATGAG TACCGTGGAAAGACACATATGTGTGTACATGAGTACAAATAAATCTTACACACACACACA CACACACACACACACACACACACACACACAAGACACATGAGTAAGCCAACTGGGGAGCTA GCTTAGTTGATAAAGTGCTTGCTATGCATGCATGAAGACCTAAGTTTGAGCCCGGCACGG TGGCACACTCTTGTCATCACAGTCGGGGGGGGGGGGGGAGGGACAAGAAAATCCCTTAGG CTCCTTATCCATGCAACGGAAGCAAATCGGCCAACCCCAGATCCCAGTAAGAGACCTTGT GATAATTTCAAAGAAGCAGCCTCCCAAGCTTGGCCTCCAACCTCCACATCCATGTGCGTA GACATGGGTGTACCAACGCAAACACATAGACGCTGACACACAGAGAAAACGCCCAGTCCC TGGGCAGAGTTCTCATCTCATACAGCTGCCCCAGCACTGTGAGGGGCCTCAGACCTCAAG AACCCTGTGCCAGCAAGACCCTGCCCCCAAAACAAAAACAAAAGCAATGGTATTAGGAAA GTCTGTCTGTCTCACATGCACTGGTGGAATGGTGAATCTCTGCCCTTACCTTATATTCAT TCAATGAGGCTCAGTCCCTGCCAAGCAGGGCCCAGTTCCAGGAGCCTCAAGGCTACACGT TGGGCCTGTTCCAGGGCAAAGAGAAGGCTGGGTTGGGTAGTGGCCAGGGTCGTGTTAAAG GAGTTGGCCGTGGGCTCACTGCTGTAGTTTCTGAGAGCTCAGATTCTTTGTTGTTACTCA GAGGGAAACTGAGGCTCAGAGGTTCTTTGGTGAACTTCTCAGGGGCTTGAGGAAAAGAGA GAGGGGCAATCCCCAGCATTTCCTCTCAGTTATTCCAAGACCCAGTCTCATTGGCCTTGT GTTCTTCTAATGCCGGCTTGACTGAGCCCCTCCTCCTCACTTCCCGACAGTTATCAGTCA GCCCAGCCCCCCCTCTCCCCAACCCGCCAAGCCACCGCTGCTCTGAGGCTGCTGGCTCAG GAGCCCCAGATTTTGCTGAGCAAGCAAAGCCAGAGGTGCTGTCTCTGCACAAACGGCCAC TGGCCAGACTTCCCTCTCTCCCTTCTCCAGGGTCTGCTTTCTAGGGGGTGTTGTAGCTTG GAGGTGGGAGTTGGTTAAGGATACAACCCACCCCCCCCCCCAGTTATTTTAGGGGCTTCA GCAAGGGGAGGGTCCTGAGGCTTCCAGAAGAGGGCATGTTTGTCTTTGGTCACACAGAAG GCCAGGGAGAGCTGAATTTTGCTCCTCACTCAAAAAAATCCAGGGGTGGCAGGAAGTGGG TCTATTATGCCTGGACTATTTGTAGACTCTTCCTGCCTGCTGAGGCCTGGTGCTTCCTCT CTGGTCTGCCTTTGTGGACTTCTATCATATTACCATTCCCAGTAACGATACCATGGCATT GATAACGTTTGAAGGGTTTCTGCCCATCCCTTTCAACTCTTGGAAGTGACAAGCACTGGG ACAATCCTATCTATGGTGTAAGGATTGATACATTTATATTCATTTGTCAGCTCAACAAAT GTGAATTGAGTTTGCACTTGGTGGTGGTTGCCTGCTGCGTACCAAGCACTGCCCAGTGCC CTAGGTTGGGGATGGTGGGTGACAAAGGTGCATGAGTCCTGCCTCGTCCCCTAAGAAAGT TCCTGCTTGGTCATTCTGCTCTTGTGACAGTTCAGTTACAGCTTGCAGTGGCTCTATTTT ACAGACGGGCAGACTGAGGCTTATGTGACAGGTATGTCACCTAGGGTTGGTCCCTGGGCT CAGTTCTGCAGGTCTTGAGTCCCCATCCTGTGTGTGCTCATGCCCTTGTTTGTTTTGCAG CCAACCCCAACAAGACGAGGGCCTCCCTGTGGGCCTCTCTGCTATCCCAGTCCCCTGGAA AAACCTAGGCCCCAGCAAAAGTAACAGGGAGTCCTCAGGAGGCCTGGTAGAAGCCTCCAC TTCCTGGGAGGAGGCCCAGGGTGAGGAACACCCGGCACCTGCTCCACTGGATGTGTCACG CCTGCGCAGTTCCTCCATGGAGATCCGAGAGAAGGGCTCCGAGTTCCTAAAGGAGGAGCT ATACAAAGCCCAGAAGGTGGGTGCTCCAGGAGAGGGTTGGGGGCTGAGGAAGAGCAGCTG CACTGAGTGAGCCCAGAAAGCTGTGGAAGGAAGGGAGAGGAGAAATCACTTGTCAAAGCC ACATGCACTGGGCGTGGTGGTGCACACCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGG CAGATTTCTGAGTTCGAGGCCAGCCTGGTCTACAAAGTGAGTTCCAGGACAGCCAGGGCT ATACAGAGAAACCTTGTCTCGAAAAAACCAACAAAACAAAACAAAACAAAACAAAACAAA ACAAAACAAAACACACATGCCAGGCCCGTGCTGGAGTCCTGAGAACTCAAAGGAAAAGGC TGGTTCAACCCAGAGCTAAGCATGCTAGGAACACAGTCCATCACTGAAGTCTCAGAGTCT AAAATGACTTTCACACATCCAGACTTACCTAGGAATCTGCTCCAGCTGGGATGGGCTGTC AGGCTAGGCTTTTAGCCTCATGCATGGGCTACCACTACCACATGGGCTACCACTGAATGT CAGATACCCAGAGCTGGTGGCTGGGGAAACAGAGTATGGTTAGGGCAGGCTAACAGCTTC CTGCCTGTACCCAGGAGCTGAAGCTAAAGGATGAAGAGTGTGAACGGCTTTGCAAAGTAC GTGCACAGCTGGAGCAGGAGCTTGAGGAGCTGACAGCCAGCCTGTTTGAGGTACGCTGGG CAGCCTGGGAACGGGTGGCCCATGTGTCCGGGCTCTGGTGACCGCTCATGCAGAGATGCT GCTCTTCTAGGAAGCTCACAAGATGGTTCGGGAAGCCAACATGAAGCAGGCGACATCGGA AAAGCAGTTGAAGGAGGCTTGGGGCAAGGTGAGACCCATCCCTGTGTGCCTAGGCCAGCC CATGGCTCCTGGCATAGCCCGTGCTAGGGGGTACTACCCTCACCTAGCAAGGGCATGCAA CAGACTCTGCTACCAAACCTACCAGACATCAAAAACAGGAGAACCCAAGTCTGGGACAGG TAGGGTGGGTCTGAAATTTAAGTAGCCCATGCACCAGACTCCATCAGTACTCTCGTTGCA CCACGGAGACTTTTCTAGGGTCCTCTGGATCCAGGAGGACCCAGTGGTTATTATAGCGTC TCCTGCCTCCAAAGCAGAAATGTCAGCCGTGGCAGTAGAACACAGGCAGGGAGTTTCCTC TCTTAGAACATCTGCCAACCAGTAAATGTGAAGCTGGGGCTGCTTTTCATGGCTTCTGGG GACCCATGAATACTTAGTGGGAACCCTAGGAAGTTCCCAGATGCCGCCTTCAGCAGAGTC TCACAATGTGACCTGAGGCAGGTCATGTCTCCTGTCAGCCTTGGGTGCCCTATCTCTAGA ATAGATAATCTTAGAGGTTGTTCCAAGGGTAAGGAGACAGGTTAGGTACTGCTGGGGATG CTTGGCTGCCAGGCTGTGGTAGCCATGGTGACATTAACCCCATGTTGGGGTTGATGGTCA TCTTGTCTGGGACAGATCGACATGCTACAGGCAGAGGTGACAGCCTTGAAGACATTGGTC ATCACATCCACACCAGCCTCTCCCAACCGTGAGCTCCACCCACAGCTGCTGAGCCCCACC AAAGCTGGACCCCGAAAGGGCCACTCACGTCAAAAGAGCACCAGCAGCTCCCTCTGCCCT GTTGTGTGCCCCACTGCAGGGCATATCCCTACCCCTGACAAAGAAGGCAAGGAGGTGAGG CACAGGCTGCAATAGTGGGCTCACAATCGGGAGGGTTGATCATGTAAACCAGCCAAGTCA GCGTCCTGAAAAAGCTATCCTGACCCCTCCTGTGGAACCTCTTTCTCTCCTCGCTGGGCT TCAGGGTTCCCTGGAACCACGAAGGCTGGGTAGGCTGATACCAAGCAGGAGGTGATAATC TTTGAACTTGAGGCTGTTAGGACCTGAAGGTCCTCTCTCAGGACATCTCTTCAGAGGTGC ATTTTCTGTGTTGAGTGATAGGTGCACTGGGGCTACCTGGTGTTTTGTGACTACAGTCTT TTTTTGTTTTTGTTTTTGTTTTTTTAAGATTTATTTATTTATTTTTATGTGTGAATACAC TGTTGCTGACTTCAGAAACACCAGAAGAGGGCATCAGATCCCGTTACAGATGGTTGTGAG CCACCATGTGGTTGCTGAGAATTGAACTCAGGACCTCTGGAAGAGCAGTCAGTGCTCTTA GCCGCTGAGCCATTTCACTAGCCCGTGATTACAGTCTTAAGGTCTAAGACCACACTGTGA CACGTGCTGAAGCAGCTACGGCCTTAGACAAATGTCTCTCTCCTGCCTCAACAGGAAATG CAGGGTGAGAGGCTTGGTCCAGGCTGGACTGACATGACCATAGGCCATTGGGTAGAATTT CCATCACTTCACACGCCACATACCATGCCTCCCTTAGGGTGAGGATAAAAAGCCAGCCTT TTTAGTATCAGAGGGTTACCGGGGAGACATGGGTGAGATTTAGCTTCCTGGACTCTTGCT CAAGCCCACCCTAGCTCAGAACTTTCTTCATCCGTCCCCTGAGCTTCTAGGAAGGAAGTG CAAGTCCTTTCAGTCCCCTTCTGAGCACCGCGCTTCCCACCGGACACTGACATCTCCTCC TTCCTCCTGTCTGTCTCTGTTTGTCTGTTTGTCTATCCATCTGTCCACCCATCCCCTGGC CCAGCCTGGGCTGCCCCCTCTACTCTCCCTGCTCCTGTGCGTGATCCCCAGCAAGGCCAT CCACCTCACCTACGAGCCGACCTGGCAGCTCCTATCTAGGGAGCCGCCCACGACCCCCAA CTCCGATACCTCTCTCTCCTTTTCCCGACAGGTAATGGCTCCTTTAGGGGCCACCCTCTC TCTCCCCCTCTGGGCTTCACTCACTGTGCATGCAGCCCAGGGCAGGCCATTGTTGCCCCT TCCAGTGGGCAGCAGGGAAACCTGTGAAATGTTCTCTCCTGTGTGCATGTACCTATATGT GTATCCTGGACATAGAGGGAAACCTGCGGGTTCCTATGGGGACCCACAGGTTCTCACAGG CTTGCTCTTGATGTTTCTTCCAAAAGGAGTCAGTAGCAGCATTCAGGCCAAGGCCTTGGA TCCAAGTCTGTAAAATTGCCGTGCCAAGAAACTTAATGTGCACCCAGACACAAACTGTGT TGTTCTTAATTCTTTGGTGCAAAGGGCAGACAGGACCTCTTCTTTGCCTGGACTCTGCTC CCTGCATGGCTGCTGAGGGCAGGCCTGATGGTCCACTGAGGCCTCCTGCATCTCCCTGCT CTTCTCTCCATCAGCTCTGCTTTCTCTGGTGTGCTCACTCTCATCCCTGACTGCCCCCAC TTGGCTCCCCTCTCCTCTAGGTGGATACGACGCTGTTTGCAGAGTTCCAAGCTTGGAGAG CTTCACCTACCCTGGATAAGAGCTGCCCCTTCCTAGAAAGGGTGTACCGGGAGGACGTGG GCCCTTGCCTTGACTTCACAGTGCAGGAGGTGAGGTGGGCTGACAGTGGTTAGCTGGGGA TCCAGCCCAGTAGTTCCCTGTCACCCAGCATCTCAATGCTCTTCCCTGATTTGTCACAGC TCTCAGCTCTGGTTCGGACTGCTGTGGAGGACAACACACTCACCATTGAGCCTGTGGCTT CACAGACACTGCCCGCTGTGAAGGTGCCCACTGTTGAGTGTAACAACACCAAGTAAGCTT AGTGTGCTGGGTCCCTTCCTGCCCACATGGGAAAGTCCAGCATGGAGCCTTGGGTAGCAC CCTGGGGGGGACTGGGATATGAGCCTGAGTCTTGGGCCTCCTAGATGGATATAGAGCCTC AGGGTGGGCAGGGACTATAACATTCAGGGTGACTGACTGTCTCCCGGGATTCATGACCTA ACCTAGGGACTCCCAAGAGATGGGCATGGGTCTGGGGGATATAGTTCAGTAAAGTCCTTG ACTAGCATGCACAAAACCATGAATCTGTCCCCAGCACCATGTAAAACCAAGTATGGTGGC ATACACCTGTGATCCAGGACTTGGGAGGTCGAGGCAGGGAGGTCAGAAGTTGAAGGTCAT TCTTGGTTACATAGCAAATTCAAGAAAAGCCTGGCCTACATAAAACCCTGCTTAAAAAAA TAAACATAATAAACCACAAGGGAGGAGCAGTCACCACTGTCTCCATGTAGGACCAGGAAT TATCTTTGACAAAGATTCCTGCTGCCAGCTGGGGTGTTTTTTTCTAGCTGTAGCCAGTCA TCCTTGCTCCCTCTCTCTCCTCTTCTGTCCCAGAGAGATACTGGGCTCTGATTGGCAAAT ATGTGATTGCTAGTGGCTGGCTCTATCCCCTGCCAATAAATAACAGCCCTGGGGTCTTAG CCTGCATACTGCTCAGCCAGCCCTGAGCAGAGGTAGCAGCAGAACTAAGAAGTTAAGGTG GCATTCCAGAGCTTGTTCAGTGGGGCTGGTTCCACAAAGGAAGCCTGGCCACACCGAGGG AACATTTGAGTCAGCTTTTTACGCAGAGGGAAAAGAATGAGTGAAGACCAGGGAACTAGA GTTTGCACTACTTCAGAGTCAGGGCATAGCCATGGAGCAGAGATCTGGGGCTGAGTCTGA GAGGGTTGCTTGATGTCAGAGTATGAAGAGCCTCTGCAAGGCAGGGCACCAACTTACTAG GGTGGTATATTAGGGGGTACCAGCTAATTCGTCCTTAAAAGAGAGTTCTCTGTTCCATTC AGCCTTACAGTCAAGGAGGAGACGACAAACACTATTAATTGTTCCTTCCCTTGGGATTCT GTAACTACTTCCTGGGTGATCTGGAAGCCACGGGGAAAGATGATGGGTTTGATGTGGCCT TTGGAGAAGCGCCTGGCTATAATGTAGAGAAGAAAGGAGTGAGGGAAAAGAGAGAGTGGT TGGAAAGAGCTGAGGAAATCCAAGCGAAAGGGCTGAGTAGTCTGGGGACATGGTGACCAA GTTCAGGTGTAGGGGTGGGAGCCAGGAGAGTTCATCACGGAGGCGGGGCCTGTGGAGGAG CAAGGTTTGGGAGCAGGAATCTGGAAGATGGGCTCTTGGTGCTAAGTGGGTTTCCTCGGC TTGACTGCGGGGAGAGGTGATGACATGGGAAAGGGATTCTTGTGAGGCTTGGTGAGCAAT ACAGGGCTAGATGAAAGTCTGGTGTGGGGATGTGAGAGGCAGCCAGACCAGAATTCAGTT AGAGAAAGAGGTGATTGGGCATAAAGACCCCAGTAATGAGGTGTGGGGGGGTTCGAGGCA GTGGAGGGTGGGGCTCTCGTATACCTGGCATAAGGTTGACCAAGCTCCTCTGCCTATGTG GGGAAAGGAACGGGGTCTGAGCATGGCTCCAGCTGCATTTAAGGTTTATCCTGAAGACTT TTGCCCTTCCCCACCTCTTTATTTGACCCTAGGCTCCTTTGGAAGATGGGAGCGGGGAGG CCAGGCCTTCCTGCCTGCCTGTCTGCTGTGCTGTGCTCACTCTCCATGCATCCTCTAACT AGGGCACATTCCCTGCATCTGTGACCCTCATTGAGCACCTTACACTTCCTCTGTTCTCCA CAGCACATGTGCCCTGAGTGGCCTGGCACGTACCTGCCACCATCGAATCCGCCTGGGGGA CTCTGACAGCCACTATTACATCTCACCGTCCTCCCGGGCCAGGGTGAGTCAGCCATCCTT CACCTTTGTGCTGGGCAAAGCTGTGTAGTGGAAGAGACTGGGGCTGAGGAGGGTCTAATG GTTTGGTATGTGATCCTTGCTTAGAGACACTGAGGTGTCGACAGAGAACACAGCCCAGGG GAGAAACTCTACCACTCTGTCTGCTGCCAGCTACTGACTATGTTGTGCCAGCCTTCTCCC CCACCCCACCCCCCAGCCTTGCTTCTCCTTCCCAGCACCAGGTTTGGCCACACCTGGCTA GTGTTCCTCTCCTTTCCCACACTACCCTGCTTGGGCAGCCTTCCCCCAGTTCCAGCTCTC TGTATCCTCTCTGGCTTCCTGGTGAGTTCCACTAGCAATAGGACCACCCCTCTTCTTTCA CTCACCAGTCTCTGGGTGCCTCACATGTAGGGCTTTCCTACCTGAGAACCCTGGGTAGGG GCTCCTGTGGGTCTGGCTGCCTGCTGCCTTCCATCCTCACTGGTTCTTTAGATGTAGAGC CTGCATGGACATTTCTGGAACTTCCTGGTGGAGGGAGGGAAGCAGGATGAGGGCAGGGAA AGGGGGGCAAGCCAAAATTGGCCTTAGCTTCAGCTAGATCCAGAAAGAGTCCCAAGCACA GAGCTACCTTCATCCTAGCCAAAGAGCTGGCTTGCATTCCCTCCACAAAATGGGCCCATG GGCTCAATGTAGCCTAAACCCTCAGAATCTGGGAGAGGGGGGCCAGGCCTGGGGATGGCC GCTGGGCAGGATAACAAGAGCGGAGTTTTTGTGGCTATGCCAGTGAAGGGTCACTAGAGC TTGGCAACAGGCCTCTCTAGCCATTCTTGGTCCTCAAGTATGGACCAAGGCAGCTCAGGG AAGTGACTGTAATTGCTTTCCCTGGAATTACACACGGCACCTAGTTTATGTCTGGCAGGC CCAGACCTTCTTGCTCCAAAGGAGCAGGTCCACAGAGGGCAGAGCTTGGCTGTTAGTGCA GGCTGCCTGATTCCATCTGCCAGCTTGGCCACTTTCTCACGCCACGCTTGACAGTCTTTA TCACAGGTAAAATGGGCACGGTGAGTGTCTGTGTCTCACTGACTGCACTGCCAACAGGCA GCTGTGGCAGGTATTCTTAGGAACAGTGGGAGTCTTGCTGTTGCTAATTAAACCTGGGAA GCCGAACTCTCCTAAAGTCAGAGAGTATTCCTTAGCTCTGCCAGGTACCTGGGACTTATT GTTATGGCTTTCAGAGGGGTCCCCTAGAGTATGGGGAATCCTGGTGGGTCACACCCTCTC CATTCTGCCCACAGATCACCGCAGTATGCAACTTCTTCACCTATATTCGCTACATCCAGC AAGGTCTGGTTCGGCAGGATGGTGAGTGCCCCCTAGTGGTCTTTTCAAGCAATAGTGCCC AAGGGAGAGACAGGGCAGAATGGGGCTGGCAGAATTGGCCTTCCAAGTCTACTTGAAAGC AGCAGCAGAGGCAGGAATCTAGGGTTGGTTCCTCCAGTAGAAGACCAAAAAAGGGGAACA CTGTAGGTTAACAAAGTTAACCTGATCCTCCTTGGTGCTGGGTTCTGTGTCACTGGAGAG CGAACCTTCCACATCACTGGCCATGCTGCCTTTTCTTCTGCATAGAAATCTCTCTATGGC AACAAAGACAGCATTCCTGTTACTAGCTTTGACATTCAAAGTTCTTTATGATGGGTCTCT CCTGTGACTCTTGCCTACTTCTTCATGCCCCCAGAAATGGCTCTCCTGCCTCCTGAGTCC TTGCTTAAAGGGCCCTTCTCCAGACACAGGGACTGGCGTCCTGGGCCCTGCTCACTGCTC TGGGGTCAGGGTGGGAAAACATTTGCAACTGGAGAAGTGTAGTTAAGCCTATTATGAAAA CAATTGTGTGCAGTGCATGAATGTCTGACCAGGCTGAGGGGTCTCCACATCACTGCCCTG CCCAAAACTGGAGAGGCGGCCAGGGCAGTTGTGTGAAGGGACCATGAACTCTTCTCTCTG TCTGCAGCTGAGCCGATGTTCTGGGAGATCATGAGGCTTCGGAAGGGCATGTCACTAGCC AAGCTTGGCTTCTTCCCCCAGGAGGCCTAGGGCATGGCCCCAGGCCTGAAGTAAGCTCTG AGCTAGAGCAAACAGCTGCCTTGGGACAGACAGACAAGAAATCCTGGAGCCAGCTCTGAG CCAGAAGCTGAAAGGACAGATAAACAACCAGGCTGTAGAGACAGTTCTGAGCCCGTACCA CCCATCCGTCCTGAGACAGACAAAAGGACAGCCTGGCCTGGACTTCATCAGATGACCCTC TTGCCCACTGAGCTCTGTAGCCAACAAGAGAATCTCAAGAAAGCACCAAAGACCAAGGTG CTCGGAGCAAGGAGCTCAGCCCTGGGGAGAGGACCCTTGAGTAGCCAGTACCCTCACACA ATCCCCTGCTGCTTACCAATGCTCTCTTGCTGCCACATCTTCAGAAAGGGGCTGCTCTAG GGTGGCTGGATTTCCAGCCCTGGGACACCAGCACCCCCTTGTGGCCATTTCTCACTCTGT TTCCAAGTGGCCTCATTAGACTGCCCCAGTGGTAGGGCAAATGTCTCCAATCTGAACAAG GTGGAGAGATAACTGCCCCGAAGTGCTCTGAAGGTGAGTCCAAGATCCCTCCTCCATTCT TCTGCATGGAGGCCTCCCTCTCCCCTTCCTCTCCACTTCAACACCATCTCCAGGAGGCCC TGTTCCTGAAGTTGCCAGGAAGTCTGGGCCCTTTCTTCCTAAAGTGTGCCACCAGGGGAG CCTCAGGACGTAACCCTGGGCAGCCATCCAGACTTCAGGGGCCCTGGATGTAGGACGGGA TGGAGAGGCTGGGCCAAGCAGGACATGGACCCTGCCTTATCCATCATAGCCCACTGGGAA CTGGGCTCGGGGGGAATCCAACCTGGACATATCCTTCACCACGCCCCTATTTCCTTCCAA TGGAATGTAACGCGATCTCTATTTAATAAAGGAAGGCTTTGTTGGTAGGGGCTAGGCGGC AGTGGCCTTCACTCCTGTGCCCTGGGGCTCTGGCCAGGGCTTGGGCATCTGAAGGAATGA AATCAAATCCTTTCCTAACTGGCCTCGTGCTTGGGATTAAACCCAAATCCTGAAGCTACC CCCATGGCTACCACCACTTTCTTGCTGTAGGGAAGACTGTTGAAGTTGTCCTTAGCTTTT CACGGAGCTATGAGGGATTGGAATGAGTTGACCACTCTCCTGAGAGTTCAGCTCTGATCT GTGAATCCCCCCAAAGCCCGTAGAGATGACCCCAAGTCTACTAGAAGCCTGGAGTCAAAA CACCCAGGCTTCCTGGGGCTGATCGATGCCACCTGTCATAGGACAGATGGGGACGACAGA AGTGCCAGGCATGGCAGGCACAAGTGGAGGTGCGGGGCAACCGGGATCCTGAGAGACCTC AGAGTAGGAATGAGGAGAGAGATGTCTTGTGGTTCTTGCCTCTGCCCAGCCAGTAGGGCT TTGTGCTTTCTGTTAGGAAGGTGCAGCAGATTCTGGGCTGGGGCAGAGGTTGTCAGTAGC CCACAGAGATTTCTCTATTGGCCTGAGGCCCAGGTGTACTCAGATGGTAGGTCAGCTGGG GGGCTGGCCAGAGCTTTGTCAAGGTCCTCTGCCGCCTTCACATGTTCTCCGGCAAGTAGC TTGTTCCCAGGACTCTGCTGCCTCCATTACCCCTCTGTTCTTATATCTCCTCCCTGCTCC ACTATGACTAGAATCCTTTGCTGTGTCCCCAGCCCCCATAGACACCTGGTCACTGACCAG ACCCTGTCGTCTCCACTCATTCACTAACTAATACTGGGGTTTTCTCTGCTGGACATTGGC CACAGCATGCATACCAGTAATATATCTGCATCCAGGTTACTGGATGGAGGGAAGTAAAAG CCAAAGGATGTCAGGGAAGGACGTGGTGTGCTGTGTGGAATCCCATGGCATCCCCTGCTA TGTCAAACCCTTGTTCACCTGGAGACAAGAGTGGATGAAAGCCTGAGCACTTTAATCAGT CTTAACTTCTGGGTTCTGGGCCCAGCCATATGCAGGACCACAAAGCCACCAGGAAACACC CAGAGGCCCACAGAGGACCTTACTCCCCTGACTTGTCCTGCTTCTACAGAGCATTGTCCA TGATCTGATGCCAGGTGGGGCCATCAACACAGCCACACCCTGCTAGTAGCAATTAATATC TAAGCACTAGTCATAGCTCGCAGCCCTCTCTGTGAACCCATTATTCCAGTCTCTTAGCAA TGTTAAAACATGCTATTATCCCTCATGTAAATGGATAGAGGCACTGGAGAACACAAAGAG GTCCTGAGGTTGGGTTTATTTACCTCAGTGGTAGAGGCTTGCCTAGCAAGTACAAGGCCC TAGCTGGTTCAGTCTCCTGCTCCAGGAAAAAAAAAGTCACAAAGGGGTCCTAAGTGTCTG GAACCTGTAGTATTAACCTACCTCTTGGTGGTTTTTTGTTGGTTGGTTGGTTGGTTGGTT GGTTTTTGTGTTTTTATACTGAACACTTTCAGTGAATGTAGGTTTTTCACCTCTTTAATT GATGCAGAAGGGTGTGAGTGTAGATCAGTGCTAGAGTGCTTAATTCAAGGTCTGAGGTTT GGTCCCAGAACCACACACACAAAACAAAAGAAACAGAGACTGGGATCGAATTGTAACCTA GGTTCCTCTGCTGTACCCTGGAAGTAGCTCAGGGCTTCGACTCTTGGGGGTGACTTGAGA GGTTAACTGCCACACCAGATGTTCTTAAATTTTCTAGATAACCCATTTGGGTTTGAAGTC TTGGCACATAGAAATCATCTGAGCTCTCCTTGGCTAGTCCTGAGTCTGGCTTCTAGGCAT GGAGGTATTAAACCTGACTAAGCACATTTACCTGGTGCAGGACCCTGAGATGTCTCACTT TACCATCTTGGTGCAGCACCTGAGATATCTCACTTCACCATCTGCCAAACCTGCCCTGAT TTGAATCCTGCCAGGGCTGTGACCTTGGAGCAAGTTGCTTTTCTCAGTTATGAATTGGGA TTATTATTCTTCCCACACAGACACAAACAATCTTCCCTCATTCACTCATTCATACAATGC ATGCATTTGGTGTTTGTGAGCTGTGCATGTGTGAATGCACATGTGCCATGGTTCACAAGG CAGAAGACAACTCTTATATTGTCTTGGTCCTCATCTTCCCCCTTGTTTGAGGAAGTCTCT CTCATTGACCCTTGAAGCATAGGTCAGGCTAGCTTCTGGGAACTGTGCCATCTCTGCCTC CCACCTTCCCACTAGGAGCATAGGGATTACAGGCATGGACTACCGGATCAAGCTTTATAA GATTTCTGCAGTTCTGGACTCAGGTCATCAGACTTTCACAGGAGGTGCTTTACCCACGAA GCAATCTCTGCCATACTTATTTTTTAAAAAAATAAAAACCTAACATGTAATCTTACACAT TTTAAAGTGTAGAATTATACTTGTGCTAGGCACATTCATACTGCCATGAAACCAAGCTAC AAACATTTTGCATCTTGCAAAACAAACACTATGCCCATTGACTAATTCCCTATTTCTCCT GCCCCTAGACTGTGGACATCAGCATTCCACCTTCTGCCTCCGTGAATCTGATTCCTCTAG AGATTTGCTGTAAATGGAAGCAGCATACTCATCTTCTAGTGACTGGCTTGTTTCACTTAA TGCAATGTCAATATCCATCCATGTTGTAAGATGACAGGATTTCCTTTTAAGACTTGGTAA TATTCTGATGTATGTGTAACAGCCCACTGTGTTTATCCATTAATTGGAGACACACACGGG TTACTGGTACCTGTTAATGTATATGCAAATATCTCTTGGAGACCCTGCATAGAGTCCTTT GAATAAATTACCGTTAGTAAATTTGCTCATA bcftools-1.21/test/csq/ENSMUST00000121418/ENSMUST00000121418.fa.fai000066400000000000000000000000221467060157400224650ustar00rootroot0000000000000019 36811 25 60 61 bcftools-1.21/test/csq/ENSMUST00000121418/ENSMUST00000121418.gff000066400000000000000000000671371467060157400221270ustar00rootroot0000000000000019 ensembl_havana gene 100 36811 . + . ID=gene:ENSMUSG00000024663;Name=Rab3il1;biotype=protein_coding;description=RAB3A interacting protein (rabin3)-like 1 [Source:MGI Symbol%3BAcc:MGI:1922010];gene_id=ENSMUSG00000024663;havana_gene=OTTMUSG00000028255;havana_version=2;logic_name=ensembl_havana_gene;version=17 19 ensembl_havana transcript 100 34017 . + . ID=transcript:ENSMUST00000121418;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-001;biotype=protein_coding;havana_transcript=OTTMUST00000070009;havana_version=1;tag=basic;transcript_id=ENSMUST00000121418;transcript_support_level=1;version=7 19 havana exon 100 648 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000709314;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000709314;rank=1;version=1 19 havana five_prime_UTR 100 648 . + . Parent=transcript:ENSMUST00000121418 19 havana exon 12311 12382 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000722123;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000722123;rank=2;version=1 19 havana five_prime_UTR 12311 12382 . + . Parent=transcript:ENSMUST00000121418 19 havana exon 13313 13474 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000721296;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000721296;rank=3;version=1 19 havana five_prime_UTR 13313 13474 . + . Parent=transcript:ENSMUST00000121418 19 havana exon 13662 13716 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000709373;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000709373;rank=4;version=1 19 havana five_prime_UTR 13662 13716 . + . Parent=transcript:ENSMUST00000121418 19 havana five_prime_UTR 24961 25156 . + . Parent=transcript:ENSMUST00000121418 19 havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00001258442;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSMUSE00001258442;rank=5;version=1 19 havana CDS 25157 25216 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 25815 25910 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144236;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144236;rank=6;version=1 19 havana CDS 25815 25910 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 25991 26068 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144231;rank=7;version=1 19 havana CDS 25991 26068 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 26716 26934 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144232;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144232;rank=8;version=1 19 havana CDS 26716 26934 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 28581 28709 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144233;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144233;rank=9;version=1 19 havana CDS 28581 28709 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 28800 28912 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144237;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSMUSE00000144237;rank=10;version=1 19 havana CDS 28800 28912 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 30784 30883 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144229;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00000144229;rank=11;version=1 19 havana CDS 30784 30883 . + 1 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 32175 32241 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00001262043;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00001262043;rank=12;version=1 19 havana CDS 32175 32241 . + 0 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana CDS 32888 32970 . + 2 ID=CDS:ENSMUSP00000113828;Parent=transcript:ENSMUST00000121418;protein_id=ENSMUSP00000113828 19 havana exon 32888 34017 . + . Parent=transcript:ENSMUST00000121418;Name=ENSMUSE00000144238;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00000144238;rank=13;version=3 19 havana three_prime_UTR 32971 34017 . + . Parent=transcript:ENSMUST00000121418 19 ensembl_havana transcript 13447 26007 . + . ID=transcript:ENSMUST00000137637;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-005;biotype=protein_coding;havana_transcript=OTTMUST00000070013;havana_version=2;transcript_id=ENSMUST00000137637;transcript_support_level=3;version=7 19 havana exon 13447 13474 . + . Parent=transcript:ENSMUST00000137637;Name=ENSMUSE00000723031;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000723031;rank=1;version=1 19 havana five_prime_UTR 13447 13474 . + . Parent=transcript:ENSMUST00000137637 19 havana exon 13662 13716 . + . Parent=transcript:ENSMUST00000137637;Name=ENSMUSE00000709373;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000709373;rank=2;version=1 19 havana five_prime_UTR 13662 13716 . + . Parent=transcript:ENSMUST00000137637 19 havana exon 24811 24871 . + . Parent=transcript:ENSMUST00000137637;Name=ENSMUSE00000805474;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000805474;rank=3;version=1 19 havana five_prime_UTR 24811 24871 . + . Parent=transcript:ENSMUST00000137637 19 havana five_prime_UTR 24961 25156 . + . Parent=transcript:ENSMUST00000137637 19 havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000137637;Name=ENSMUSE00001258442;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSMUSE00001258442;rank=4;version=1 19 havana CDS 25157 25216 . + 0 ID=CDS:ENSMUSP00000120366;Parent=transcript:ENSMUST00000137637;protein_id=ENSMUSP00000120366 19 havana exon 25815 25910 . + . Parent=transcript:ENSMUST00000137637;Name=ENSMUSE00000144236;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144236;rank=5;version=1 19 havana CDS 25815 25910 . + 0 ID=CDS:ENSMUSP00000120366;Parent=transcript:ENSMUST00000137637;protein_id=ENSMUSP00000120366 19 havana exon 25991 26007 . + . Parent=transcript:ENSMUST00000137637;Name=ENSMUSE00001000272;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSMUSE00001000272;rank=6;version=1 19 havana CDS 25991 26007 . + 0 ID=CDS:ENSMUSP00000120366;Parent=transcript:ENSMUST00000137637;protein_id=ENSMUSP00000120366 19 ensembl_havana transcript 13475 25908 . + . ID=transcript:ENSMUST00000149967;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-006;biotype=protein_coding;havana_transcript=OTTMUST00000070014;havana_version=2;transcript_id=ENSMUST00000149967;transcript_support_level=2;version=7 19 havana exon 13475 13716 . + . Parent=transcript:ENSMUST00000149967;Name=ENSMUSE00000811640;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000811640;rank=1;version=1 19 havana five_prime_UTR 13475 13716 . + . Parent=transcript:ENSMUST00000149967 19 havana five_prime_UTR 24961 25156 . + . Parent=transcript:ENSMUST00000149967 19 havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000149967;Name=ENSMUSE00001258442;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSMUSE00001258442;rank=2;version=1 19 havana CDS 25157 25216 . + 0 ID=CDS:ENSMUSP00000120401;Parent=transcript:ENSMUST00000149967;protein_id=ENSMUSP00000120401 19 havana exon 25815 25908 . + . Parent=transcript:ENSMUST00000149967;Name=ENSMUSE00000760118;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00000760118;rank=3;version=1 19 havana CDS 25815 25908 . + 0 ID=CDS:ENSMUSP00000120401;Parent=transcript:ENSMUST00000149967;protein_id=ENSMUSP00000120401 19 ensembl_havana transcript 16624 33887 . + . ID=transcript:ENSMUST00000113161;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-004;biotype=protein_coding;ccdsid=CCDS29569.1;havana_transcript=OTTMUST00000070012;havana_version=1;tag=basic;transcript_id=ENSMUST00000113161;transcript_support_level=5;version=8 19 ensembl_havana five_prime_UTR 16624 16779 . + . Parent=transcript:ENSMUST00000113161 19 ensembl_havana exon 16624 16790 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000763287;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSMUSE00000763287;rank=1;version=1 19 ensembl_havana CDS 16780 16790 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00001306809;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00001306809;rank=2;version=1 19 ensembl_havana CDS 24961 25216 . + 1 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 25815 25910 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000144236;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144236;rank=3;version=1 19 ensembl_havana CDS 25815 25910 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 25991 26068 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000144231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144231;rank=4;version=1 19 ensembl_havana CDS 25991 26068 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 26716 26934 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000144232;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144232;rank=5;version=1 19 ensembl_havana CDS 26716 26934 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 28581 28709 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000144233;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144233;rank=6;version=1 19 ensembl_havana CDS 28581 28709 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 28800 28912 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000144237;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSMUSE00000144237;rank=7;version=1 19 ensembl_havana CDS 28800 28912 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 30784 30883 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000144229;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00000144229;rank=8;version=1 19 ensembl_havana CDS 30784 30883 . + 1 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 32175 32241 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00001262043;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00001262043;rank=9;version=1 19 ensembl_havana CDS 32175 32241 . + 0 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana CDS 32888 32970 . + 2 ID=CDS:ENSMUSP00000108786;Parent=transcript:ENSMUST00000113161;protein_id=ENSMUSP00000108786 19 ensembl_havana exon 32888 33887 . + . Parent=transcript:ENSMUST00000113161;Name=ENSMUSE00000694553;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00000694553;rank=10;version=2 19 ensembl_havana three_prime_UTR 32971 33887 . + . Parent=transcript:ENSMUST00000113161 19 ensembl_havana transcript 16625 33886 . + . ID=transcript:ENSMUST00000117641;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-003;biotype=protein_coding;havana_transcript=OTTMUST00000070011;havana_version=1;tag=basic;transcript_id=ENSMUST00000117641;transcript_support_level=1;version=7 19 havana five_prime_UTR 16625 16779 . + . Parent=transcript:ENSMUST00000117641 19 havana exon 16625 16790 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000712628;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSMUSE00000712628;rank=1;version=1 19 havana CDS 16780 16790 . + 0 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00001306809;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00001306809;rank=2;version=1 19 havana CDS 24961 25216 . + 1 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 25815 25910 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000144236;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144236;rank=3;version=1 19 havana CDS 25815 25910 . + 0 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 25991 26068 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000144231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144231;rank=4;version=1 19 havana CDS 25991 26068 . + 0 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 28581 28709 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000144233;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144233;rank=5;version=1 19 havana CDS 28581 28709 . + 0 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 28800 28912 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000144237;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSMUSE00000144237;rank=6;version=1 19 havana CDS 28800 28912 . + 0 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 30784 30883 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000144229;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00000144229;rank=7;version=1 19 havana CDS 30784 30883 . + 1 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 32175 32241 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00001262043;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00001262043;rank=8;version=1 19 havana CDS 32175 32241 . + 0 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana CDS 32888 32970 . + 2 ID=CDS:ENSMUSP00000113551;Parent=transcript:ENSMUST00000117641;protein_id=ENSMUSP00000113551 19 havana exon 32888 33886 . + . Parent=transcript:ENSMUST00000117641;Name=ENSMUSE00000711500;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00000711500;rank=9;version=1 19 havana three_prime_UTR 32971 33886 . + . Parent=transcript:ENSMUST00000117641 19 ensembl_havana NMD_transcript_variant 16625 36811 . + . ID=transcript:ENSMUST00000144788;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-002;biotype=nonsense_mediated_decay;ccdsid=CCDS29569.1;havana_transcript=OTTMUST00000070010;havana_version=1;transcript_id=ENSMUST00000144788;transcript_support_level=1;version=7 19 havana five_prime_UTR 16625 16779 . + . Parent=transcript:ENSMUST00000144788 19 havana exon 16625 16790 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000712628;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSMUSE00000712628;rank=1;version=1 19 havana CDS 16780 16790 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00001306809;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00001306809;rank=2;version=1 19 havana CDS 24961 25216 . + 1 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 25815 25910 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000144236;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144236;rank=3;version=1 19 havana CDS 25815 25910 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 25991 26068 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000144231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144231;rank=4;version=1 19 havana CDS 25991 26068 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 26716 26934 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000144232;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144232;rank=5;version=1 19 havana CDS 26716 26934 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 28581 28709 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000144233;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144233;rank=6;version=1 19 havana CDS 28581 28709 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 28800 28912 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000144237;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSMUSE00000144237;rank=7;version=1 19 havana CDS 28800 28912 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 30784 30883 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000144229;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00000144229;rank=8;version=1 19 havana CDS 30784 30883 . + 1 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 32175 32241 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00001262043;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00001262043;rank=9;version=1 19 havana CDS 32175 32241 . + 0 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana CDS 32888 32970 . + 2 ID=CDS:ENSMUSP00000121449;Parent=transcript:ENSMUST00000144788;protein_id=ENSMUSP00000121449 19 havana exon 32888 33513 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000730629;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00000730629;rank=10;version=1 19 havana three_prime_UTR 32971 33513 . + . Parent=transcript:ENSMUST00000144788 19 havana exon 36489 36811 . + . Parent=transcript:ENSMUST00000144788;Name=ENSMUSE00000761960;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000761960;rank=11;version=1 19 havana three_prime_UTR 36489 36811 . + . Parent=transcript:ENSMUST00000144788 19 ensembl_havana transcript 16696 26739 . + . ID=transcript:ENSMUST00000131407;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-007;biotype=protein_coding;havana_transcript=OTTMUST00000070015;havana_version=2;transcript_id=ENSMUST00000131407;transcript_support_level=5;version=1 19 havana exon 16696 16790 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00000694573;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000694573;rank=1;version=2 19 havana five_prime_UTR 16696 16790 . + . Parent=transcript:ENSMUST00000131407 19 havana exon 16913 17008 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00000807397;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000807397;rank=2;version=1 19 havana five_prime_UTR 16913 17008 . + . Parent=transcript:ENSMUST00000131407 19 havana exon 24811 24871 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00000805474;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000805474;rank=3;version=1 19 havana five_prime_UTR 24811 24871 . + . Parent=transcript:ENSMUST00000131407 19 havana five_prime_UTR 24961 25156 . + . Parent=transcript:ENSMUST00000131407 19 havana exon 24961 25216 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00001258442;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSMUSE00001258442;rank=4;version=1 19 havana CDS 25157 25216 . + 0 ID=CDS:ENSMUSP00000115976;Parent=transcript:ENSMUST00000131407;protein_id=ENSMUSP00000115976 19 havana exon 25815 25910 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00000144236;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144236;rank=5;version=1 19 havana CDS 25815 25910 . + 0 ID=CDS:ENSMUSP00000115976;Parent=transcript:ENSMUST00000131407;protein_id=ENSMUSP00000115976 19 havana exon 25991 26068 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00000144231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144231;rank=6;version=1 19 havana CDS 25991 26068 . + 0 ID=CDS:ENSMUSP00000115976;Parent=transcript:ENSMUST00000131407;protein_id=ENSMUSP00000115976 19 havana exon 26716 26739 . + . Parent=transcript:ENSMUST00000131407;Name=ENSMUSE00000762446;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000762446;rank=7;version=1 19 havana CDS 26716 26739 . + 0 ID=CDS:ENSMUSP00000115976;Parent=transcript:ENSMUST00000131407;protein_id=ENSMUSP00000115976 19 ensembl_havana aberrant_processed_transcript 30101 32241 . + . ID=transcript:ENSMUST00000129882;Parent=gene:ENSMUSG00000024663;Name=Rab3il1-008;biotype=retained_intron;havana_transcript=OTTMUST00000070016;havana_version=1;transcript_id=ENSMUST00000129882;transcript_support_level=5;version=1 19 havana exon 30101 30883 . + . Parent=transcript:ENSMUST00000129882;Name=ENSMUSE00000840450;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000840450;rank=1;version=1 19 havana exon 32175 32241 . + . Parent=transcript:ENSMUST00000129882;Name=ENSMUSE00001311728;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001311728;rank=2;version=1 19 NCBI biological_region 957 1311 . + . external_name=B6Ng01-19B17 (start);logic_name=mouse_b6ng01_clones 19 NCBI biological_region 960 1629 . + . external_name=DN-478K15 (end);logic_name=mouse_dn_clones 19 tRNAscan biological_region 1653 1721 45.7 - . external_name=Ala;logic_name=trnascan 19 NCBI biological_region 4551 5246 . + . external_name=DN-89E5 (start);logic_name=mouse_dn_clones 19 NCBI biological_region 4571 5479 . + . external_name=DN-272A18 (start);logic_name=mouse_dn_clones 19 NCBI biological_region 7405 8067 . - . external_name=C3H-150K16 (start);logic_name=mouse_c3h_clones 19 NCBI biological_region 8286 9024 . + . external_name=B6Ng01-20H24 (end);logic_name=mouse_b6ng01_clones 19 NCBI biological_region 8354 8407 . + . external_name=BMQ-318L18 (end);logic_name=mouse_bmq_clones 19 NCBI biological_region 10211 10453 . - . external_name=BMQ-454B11 (end);logic_name=mouse_bmq_clones 19 NCBI biological_region 10555 11599 . - . external_name=B6Ng01-220C17 (end);logic_name=mouse_b6ng01_clones 19 tRNAscan biological_region 10584 10656 20.8 + . external_name=Pseudo;logic_name=trnascan 19 NCBI biological_region 11388 12114 . + . external_name=BMQ-97M19 (start);logic_name=mouse_bmq_clones 19 NCBI biological_region 11639 11976 . + . external_name=RP24-273B16 (end);logic_name=mouse_rp24_clones 19 NCBI biological_region 11641 12404 . + . external_name=DN-80O15 (start);logic_name=mouse_dn_clones 19 NCBI biological_region 11805 12199 . + . external_name=RP24-308A8 (end);logic_name=mouse_rp24_clones 19 NCBI biological_region 13122 13748 . - . external_name=WI1-343B18 (end);logic_name=mouse_wi1_clones 19 . biological_region 13429 13716 0.591 + . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 14175 14562 . + . external_name=RP24-307D21 (start);logic_name=mouse_rp24_clones 19 NCBI biological_region 14399 14887 . + . external_name=WI1-2823N24 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 14403 14840 . + . external_name=WI1-2823L2 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 14455 15614 . - . external_name=B6Ng01-296M4 (start);logic_name=mouse_b6ng01_clones 19 NCBI biological_region 15059 15531 . - . external_name=RP23-26O6 (start);logic_name=mouse_rp23_clones 19 . biological_region 15601 16369 0.975 - . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 15615 16218 . + . external_name=RP23-261J14 (end);logic_name=mouse_rp23_clones 19 NCBI biological_region 15624 15952 . + . external_name=RP23-405E18 (start);logic_name=mouse_rp23_clones 19 NCBI biological_region 15633 16447 . + . external_name=CH29-612C19 (end);logic_name=mouse_ch29_clones 19 NCBI biological_region 15642 16471 . + . external_name=CH29-612G16 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 16065 16838 . + . external_name=BMQ-49J16 (end);logic_name=mouse_bmq_clones 19 . biological_region 16723 16790 1 + . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 17806 18840 . - . external_name=B6Ng01-140B2 (end);logic_name=mouse_b6ng01_clones 19 NCBI biological_region 18631 19171 . + . external_name=C3H-98E14 (start);logic_name=mouse_c3h_clones 19 tRNAscan biological_region 18956 19029 21 - . external_name=Pseudo;logic_name=trnascan 19 NCBI biological_region 19039 19741 . + . external_name=B6Ng01-245C24 (start);logic_name=mouse_b6ng01_clones 19 NCBI biological_region 19067 19945 . + . external_name=DN-401M8 (end);logic_name=mouse_dn_clones 19 NCBI biological_region 19379 19898 . - . external_name=WI1-2459M12 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 19481 20197 . + . external_name=B6Ng01-207H22 (start);logic_name=mouse_b6ng01_clones 19 NCBI biological_region 19614 20033 . + . external_name=WI1-681J5 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 19749 20403 . - . external_name=RP24-122K13 (end);logic_name=mouse_rp24_clones 19 NCBI biological_region 20487 21008 . - . external_name=WI1-2445M19 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 21739 22457 . + . external_name=DN-408F20 (end);logic_name=mouse_dn_clones 19 NCBI biological_region 21877 22515 . + . external_name=DN-112H24 (end);logic_name=mouse_dn_clones 19 NCBI biological_region 21964 22362 . + . external_name=WI1-2577M12 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 21985 22413 . - . external_name=RP24-241J2 (start);logic_name=mouse_rp24_clones 19 NCBI biological_region 22330 22816 . + . external_name=WI1-1162H10 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 23363 23832 . - . external_name=WI1-1861P3 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 24063 24249 . + . external_name=WI1-367E5 (start);logic_name=mouse_wi1_clones 19 tRNAscan biological_region 27367 27438 24.6 - . external_name=Pseudo;logic_name=trnascan 19 NCBI biological_region 27374 28143 . + . external_name=RP24-306J20 (start);logic_name=mouse_rp24_clones 19 NCBI biological_region 28389 28985 . + . external_name=MSMg01-309J15 (end);logic_name=mouse_msmg01_clones 19 NCBI biological_region 28389 28988 . + . external_name=MSMg01-388E6 (end);logic_name=mouse_msmg01_clones 19 NCBI biological_region 28389 28990 . + . external_name=MSMg01-309I15 (end);logic_name=mouse_msmg01_clones 19 NCBI biological_region 29840 30078 . + . external_name=RP24-343G14 (end);logic_name=mouse_rp24_clones 19 NCBI biological_region 29865 30216 . - . external_name=WI1-1545O2 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 30440 31287 . + . external_name=CH29-530C15 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 30450 31300 . + . external_name=CH29-604H22 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 32425 33314 . + . external_name=MHPP-12P5 (end);logic_name=mouse_mhpp_clones 19 NCBI biological_region 33358 33729 . + . external_name=WI1-284I18 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 35118 35401 . + . external_name=WI1-2318A14 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 36009 36283 . + . external_name=WI1-2527J17 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 36365 36884 . - . external_name=C3H-207A12 (end);logic_name=mouse_c3h_clones bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.1.cmd000066400000000000000000000002661467060157400230010ustar00rootroot00000000000000{bin}/bcftools csq -f ENSMUST00000121418.fa -g ENSMUST00000121418.gff filter-problem.vcf -i 'POS!=25105' --phase m | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.1.cmd.out000066400000000000000000000002401467060157400235770ustar00rootroot0000000000000025105 G A . 25496 ACAAA ACAAAGCAAA intron|Rab3il1||NMD,intron|Rab3il1||protein_coding 25500 AACAA AACAAGACAA intron|Rab3il1||NMD,intron|Rab3il1||protein_coding bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.2.cmd000066400000000000000000000002661467060157400230020ustar00rootroot00000000000000{bin}/bcftools csq -f ENSMUST00000121418.fa -g ENSMUST00000121418.gff filter-problem.vcf -i 'POS!=25496' --phase m | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.2.cmd.out000066400000000000000000000010251467060157400236020ustar00rootroot0000000000000025105 G A 5_prime_utr|Rab3il1|ENSMUST00000121418|protein_coding,5_prime_utr|Rab3il1|ENSMUST00000131407|protein_coding,5_prime_utr|Rab3il1|ENSMUST00000137637|protein_coding,5_prime_utr|Rab3il1|ENSMUST00000149967|protein_coding,synonymous&NMD_transcript|Rab3il1|ENSMUST00000144788|NMD|+|52E|25105G>A,synonymous|Rab3il1|ENSMUST00000113161|protein_coding|+|52E|25105G>A,synonymous|Rab3il1|ENSMUST00000117641|protein_coding|+|52E|25105G>A 25496 ACAAA ACAAAGCAAA . 25500 AACAA AACAAGACAA intron|Rab3il1||NMD,intron|Rab3il1||protein_coding bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.3.cmd000066400000000000000000000002661467060157400230030ustar00rootroot00000000000000{bin}/bcftools csq -f ENSMUST00000121418.fa -g ENSMUST00000121418.gff filter-problem.vcf -i 'POS!=25500' --phase m | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.3.cmd.out000066400000000000000000000010251467060157400236030ustar00rootroot0000000000000025105 G A 5_prime_utr|Rab3il1|ENSMUST00000121418|protein_coding,5_prime_utr|Rab3il1|ENSMUST00000131407|protein_coding,5_prime_utr|Rab3il1|ENSMUST00000137637|protein_coding,5_prime_utr|Rab3il1|ENSMUST00000149967|protein_coding,synonymous&NMD_transcript|Rab3il1|ENSMUST00000144788|NMD|+|52E|25105G>A,synonymous|Rab3il1|ENSMUST00000113161|protein_coding|+|52E|25105G>A,synonymous|Rab3il1|ENSMUST00000117641|protein_coding|+|52E|25105G>A 25496 ACAAA ACAAAGCAAA intron|Rab3il1||NMD,intron|Rab3il1||protein_coding 25500 AACAA AACAAGACAA . bcftools-1.21/test/csq/ENSMUST00000121418/filter-problem.vcf000066400000000000000000000007351467060157400226560ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO 19 25105 . G A . PASS . 19 25496 . ACAAA ACAAAGCAAA . PASS . 19 25500 . AACAA AACAAGACAA . IndelGap . bcftools-1.21/test/csq/ENSMUST00000133836/000077500000000000000000000000001467060157400172355ustar00rootroot00000000000000bcftools-1.21/test/csq/ENSMUST00000133836/ENSMUST00000133836.fa000066400000000000000000001470271467060157400217660ustar00rootroot00000000000000>19 19:10941382-10993250 TGTACATAGCCAATGCCAGGCCCAAGTCTTGGGGAGGGTCCAGGCAACCAGCTTATGGAA GTGTCCTGAGTGACTCAATCTCCCGGAGCAAGGTGAATTGAAGCAGTCCTTTTAAAACAC TTTAATCTTGCAGTATGGACCTGGGAGAGCAACAAGATGCAAAAGTAGCCATCGAGGAGT TACCTGGCTCTTGACTGCTGGCCTCCAGGTTTCTACACATTTAAGAGCAAAAGTACTTAA TTGCCTAGGGATCTTGCTAGGGTAACTGATAAGGGTCGGGTAAAATTTTGTATTTCTATT ACCTTCCTGGCAGCTCGCCCAAGGCACTTGGGAATCACACAGGTTAAGCTCACAGCCTGC ATCTCATAACTCCCTGCTTTGTGAATGGGACAAAGGGAGTCGGCCAATCAGTATTTATGG GGGTCAGTGAGAGGAAAAGGGTTGAGACCAGCCAACTGCCATCATTTTTAATCCCCCATT TGGCCTGAGACAGGTGCTTTAACCACACCTTGCTAGTCAGCTTGTTATTGTTATATATGG TGATATGGATGTGTCAACTCCCACTAGGGATTTTCACTGCCCAGTTTTAGGGCTGCTGCT GCTGGCTTTCAGCAGCACTGGATCAATTCTAGGCAGAGAGAACAACCTACCCTTATTAGC TGCCTGGCAGGGAGAGGGCCTGGCAGCCATCACTTCCAACCTACAGGTAGGAGGGGCACC TGTGCCAGTCATGGACCTTCTATCACACATTTCATGTCCTCCCCATCATAGACTGCAGGG AAGCTGGCTGATTCCTCTTTACCTTCTAGGGGAAGGGGAGCTGATGTCAGAAATTGGTAA ATATGGAACAGGGATGGGGTAGTCTCAGGATCTCCTGAACCACGCAAGGCCAGGCTGGTT GTCAGTTGTGTTGAGCAGGCCTCAAGCCTGTGGCAGGCGCTTCTCAAACTGGAGAGTAAA ATGTCACCAAGTCCCTCCTGCTTTACTCAGTGTACCTGTCACACCATTATTTCAATGGTT TATTATGATAATGAAAGCCAAGTGGGGCAGGGGCTTCTGTCCTTCGGGGAGCCCAGAGCT GTACTTATGCAGATACCAATAAACACCTCTGCAATAGAGCAGGTAGGTATGACTCAAGCC TCGAGGCTTCTACAGTCCAGTGTGGCAAAGGGGTGCTGGAGAGAAACTCAGCTCCCTGTA ACACCCTACTTTAATCTTTTAGTGCTAAACTAGGGAAAGGCTAGCTTCAGTTGACTGAGG GGACCAAATCAGTAGAATCCACAAGTGGCCAAGATGTCACTGAAAAAATGGAGGTACTGA CTTCTGACAGCAGACCTTCAGGCGTGGGTAACACCCAGGACCCCAAGTCAGGGATTTATT AGCTCACTGGGAAACAAGAATTCACAGCTGAAGACCTCTTTTGTTGTTTTGATTTTTTTT TTTTTTAGATACGACTTCTCTGTGTAGCCCTGGCTATCCTGTACTCTATAGACAAGACTG GCCTCGAACTCTGAGAGCTGCCTGTCTCTGTCTCCTGAGCACGGGGATAAAAGGTGTGCA TTGCTGCAACCACCCAGCAACAGTTTATGACTATAAGGCACTTTGGAACAGGCGGGAAAG GAGATGGGGACAGTTAAATCTCTCTTGAGTCCCAGCATAGTCGTCAGTTCCCTCTGGGCT GGAGTCTCCGTCTTAATGTGACAGCGTTGGTGTGCTGGCTCCAGGAGAGGTGTCAGTCAG TGGCCTGAGAAGTGCCTTGTTTGCTGAGGCCTATGGACTGTCCTGAACTCAGACCTTGGC TACAGGCCTCTGGGGTGGCTGTTTCTGGAGCAAGGCCAGGGTGTCTCGTTTTTCAATAGA ACGCAACTGCTTCTTCTTTGCTTTCTTGAGCTTGGCAGGATTGCGGATCTGAGGAGGAAA TAGGAGGCATCAGTGTGGATGAGAACCCTCTGCTTATCTTTGAGGAAAAGGAGACGGGAG GGGGGCAAGGGCCCAGAACTGCAGCAGGACAATGAACCATGTAATACAGGGGGCCCAAGC ACCTTAACGGCCTCTTTCACCATGCCACAGCCTGCATCCCTTGGGTGGGTACTCACCACT TGGACAATCTCAGCCTTGCGCTCATTTTCTAGACGGCGTCTCAGGTTTTCAGCCCGGCGC TCTTTCTTCTCCTGAAACACAGAGAAGAGCAATCTCAGGCTAGGAACTGAGATGGTCTAG GCATCTTAGGCCACTGGTGAGTGAGAACTGACACAATCCTAGGAGGAAGGGTAGAGGCCT AGGCACTTCTGGGGGAAGAACAGGGATGCAATGCCTGCAATGAGGGCCTGGAGCTGAGGC CCACCACGGCAAGAGTACCCAGTTCCAAATCAGAGACCCTGAAGGCAGGGTCTTACACAG GATGACTGTATGGGCCAAGATGTGGGTGCCTTCCCGCTCAGAAGTCACATACAAGCAGAA TGGCCCCTTGTGCTAGCTGCCAGAAGGTTGGGGCTGGTTCCAGGTTTTCTTCTGCCCTGG CTCAGGTGTCCCAGAATGAGAATGCAAGGTCAGGTTACAGCTGGGCTCCGCACCTGGCCC TGGGTAGGGGTGGGAAGGATGAACTGTCCAAGGCTCTGGAGGAACCTAGTCCAGCCTGAG TCTTCATTCTTCTACTTTCGAATTAGGGTGCTGTGGCTGAGCCTGTACCTTCACTTCCTC ACTGCTACAGTAAAGTTGACCACAGGACCTACCTCATCAGGCTGACTTAAGAAATACGTG TGTGACTAAAGCCTGAAATAGTACCAGCTCTCCAGGGACACTCAGAGCCTGTTCTGGGGG TGGGAAGTCCAGGGTTTCCTGCCACTGTACTAGCAGAGCTAGGGCATGGATGATGGCTCC AACATTGATGGCTATGTGGTTAGGTCTTTCTGTGGCTCTGACAACCTGGGGTCATGGGGT TGGCCTGGGCCCTTGGGGAGGAAGTGACCCGTGCTCCTATGTATTAGGAGGAGGGCTGGG AGGATGCACCTCTCTAGTTGCTCACGAGTTGGCAACTGTTTTGGCCAAGCAGGAGTCTAG GCTGCACAGGAAAAATGACAGGGCCTCAGTGCCAGCTAGATCTGGAACGACTCAAAGCTA GGTGGAGGGATGCCTTAGTGATTGGTCCATCCCTCCACCCAGTGGCCAAGCTGGAACCAC AGATTTGAGACAAGTCATTTGAATCAGTGCTCCTTCTGTACCCTGGGCTCACCAGACTAG CAGTGATAGCTGAACTCGGTCCTGGGGACAATCCTGCTAACCAACCCAGTATGACCTTGC TTACTCAGTACTGACTGCTAAAGTAAAACTGGGGCTCTTTTCAAGACTTCCTGGAGGCTA AAGGTGTTGGGAATAAGCCTTTGTGGTGTTGGTGACTGAGCCCAAGGCTCTGTGCATGCT TGTCAAGTCTCTAGCTCATGATCATGAACCTCTAATGAGGACATTTTTGGTTCTGAGATG GTAGAAAGGGGAGTGAACTGGAAGCAAAGTGAAAGGACCATCTCCATGGTGGTGTGTGGG AGTCTCTTCTAGAATGACAGTGACAAATTTGAGGCAAGCTTTTCCCTCATAAGCAGGTCT CAGAGAGGGGTCTGACCCCACCACATTGAATGCTGCTGCCACCAAGTTGGCCTGCTGGCT TTTATCTCAGGCTCACTCTACTTCCAGGTCTCCTCCATGTCCATGAGAGCAGAAGCTTAG CTGGATGGTAGAGTGGGAATCCTATCATGACCCTCGACTATTCTTCTTACCTCTGGGGCC CTCATGACCAGGGGCTCTGACTAAGTCATACTCCTGTGCCTATCATGTGCCTGTCCAGTG TCTGTTGCAGCAGATAAGTGTTTGTCGTCTGGGATCCAGGCTTGGAGGAATGGTCCCTTA CCTGCCGGCGCCTCTGTTTCTCCTCCTCCAGGTGTCGGGCGAAGTCCTTAGCCAGCTTTC TCTCCTGTCGCTCCTTCATCTTCCGCTGCCAGGAGGTACGCAGGGGCTTGTCCTGAACCA TCTGGGAGAACCTTGGCAGGAGAGGAGGCAGTTGGGGGACCTCTGTGGTGCTGCCTTCAT ACACTGCTCTCACTGAGCTCTGGGTCTGCTCTTTTTTCTTTTTTAACTGAATATTTTCTT TACATTTCAAATGTTATCCCTTTTTCTGGTCCCCTTCTTCCCCCACCCCAGAGCCCCGCT ATCCCATCCCCCCTCCTCCTGCTTCTATGAGGGTGTTCCCCCACCCACCCATTCCCTCTG GGTCTGCTTCTTGTCCTCTCCTACCTGCCTGGCATTCAGCTTTCTACAGAAACTTAGGAT GGAACAGGTTGCTAAGCATGTAGGCCTGTTTCCTCTACAGAGGAACTAACCAAGACTTCA AAAGTCCTCTCATTCCTGAGTGTAGATTGAAGATTTTTTTTTTTTTTTTCCGAGACAGGG TTTCTCTGTATAGCCCTGGCTATCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAAC TCAGAAATCCGCCTGCCTCTGCCTCCCAAGTGCTGGGATTACAGGCGTGCGCCACCACTG CCCGGCTGACTTGAAGCCTTTTGTGCTAATATAGCCTCAGCTGTGAAATTTGCTGCCACC AAACATGATAAGCTCGGAGTGAATGCTTCTGGAAATGAGATACTCATGCCCTAGAGGGGT GTGCAATAACAAGGCCTTTTTGTAACAAATTCAGATTATTCTCCAGTTTGGGAGATGTGA AGGTAGAGAACTGGGATTTGGGGATTTCTGTTAAGTGTGGCTTTTCTGAAGAGTCAAATG TTCTTAGAGTCATAGAAGAATGGAGATGACATCTGTAAGAACACTCTAGGGTGGGCTGAA ACATTCCAGGAGGGGGTAAGTGCAGGGACAAGGAACAGAAGATTAAGCTGAGCCATGAAA TGCTGAAAACTGTTGCAACTGGTGATAGGACTCCTAAAACTCAGCTCTTTCCTTTTCTGT AATAAAAAGTAAAAATAAAATGAAGACAAGCCTTCATGTCTGGTCTCTCTCCTACTCCTT GCTGAGTGTGCTGGGTGTCCCATGGGCCTGTTTTCTCCCCCATCTTATCCCTAGAACTCT AAGGCTCCTCAGCAGATCCGTTCACAGTGGCCCTTCTGCTTCCTACACTAAAACCTTGAC TCCTGTAGGAGTTCCTTTTTACCTGCCTGTTATAGGGTAGCTCAAGCCAACCCTGTGTCT AAAGGCTTGGTGCATGCTGGGCAGTCTGTTGCTGACCAGACAAAGGTCAATACGGCCTTT CTGAGCCACCTGCTTCCTTCCTAGGAGTCTGGCACACACAGTTTGGAACCTGGCACCAGG CTTATCCATAGGCATCCTGTTTCTGTCCCCTTCCCACTGTAAGGTTCAATAGTGATACAA ACATGCTCCTCTCCTGCCAAGTTCGCCAGCTGGCTCAAGACCCAGCTTCCTAAACACAGA GCAGTGGTGCCTTGTGGACTTCCTTTCTACTCTTAAAAATGTGGCTCGTGACTGCAGTAC TGAGGCAGAGTTGATGTTCAGCACTAGTTACTGGAGATGGAAGACAGGCTCCGAGCCCAT TACTCACTGCCTATGCGAGCCTGTGCAAGGAAGCCTCTCAGCCACCGCGCCCTTCTGTGT GCGAGCCCGTCTGGCTGGTCACCCGTGGCCATCAGTGGCCTGTATTGTGGTTTGCTCGGA CAGGGAAAAGGAACAGCTTCAAAGTTTCTCCGCTTGGTGCCTTTCTCTTTAAGCCTCACT TTCCTCTGTTTAATGGGGTGTGCTTGCGGGAGGGGTTATCCCCTGCGCTTAGGATTTAAG AGTATAACAAAATGACTTCTGTAAAGAGCCTGCACGGAGCCTCGCACGGTCCACCCTTAT TCAACGTCATTTTCTTAAAATCTCTGATGCCCTGCTCCCTTACTCTTACGAGTTCTTGTC TCTGGCCAGTAGCTGACACTTCAACTGAACCCTACTTCTCCTTCTCCAGACACTGTCACA ATGTCTCCAGACATTGTCACAGACACTGTCTCCATCCATGTCACAACAGTGGACATTTCA ACTGAATGCCACTTCTCTTCCCCTGCTGCCTAAACAATGTCCTTTCCACATGAGCCTCCT TCCTCATTCCTTTACTGAGAAATCTAAACTGAGCACTCCCATGCCCCAGCACTGAAGGGA CAGGGAAGACCTCATGTCTTAAGAAGGCTGGAACCCAAGGGAAGCTGGCCACCAGAAGCA GGTTAACGGGTTCACTCACACGCTTTGCAATCAAACCTATGCTCCCATCCCGTGTCTCAG TTAGCCTCCTTGAGCCTTGGCTTCCTCAGATGTACAACACCAATCCTAGTAACACCTGCT CCAAAGGGTAGATGATTACATGTGCTGCTGGCTATGAAAGCCTCTCTCTTTGGCCATCCT TACCGTGATACATAACCAGTGTCCCATGATACATTTTTTATCAAAGACAACAGCTAGCAG ACAACAGTGGAAAGGACCTCACTATGTTCATATAATGGCCGCCTTTCTTGCTCTGCCTGC CACACGAGATGTGGCGGACAAGGTAAAGGTGGCACGTCTATAAACCCAGCACTAGGGAAG CAGAAGCAGGTGTATCTCTGAATTTCAGGACAGCCAGTGCTATACAGTGAGACCCTGCCT CATAATAAAAAAAGGATGGGAAGAAAGCTCAAAAGAACACCGTCTAGGGCAGACATTAAA GAAATGATCTTTGAGGATCTATCTCCCTCCCCGACCTTAGGGCATTTTGACATTATGATC GTGTTTGTTAATTTCATTCGGGTGAACTCTTTACAACCCTTGGATTGCATTCAGGCGAAG GCAAGGTCCAAATGTACTAAGAACCCAACACATCACCCATGCTACCCCCACTTTACCTCT TCTTGGAGCGGTCTTTCCACACACGCCCGGATTTGGGCTTCCCTTTCGGAATTACAGGAA GCTCCTCCTTCTCTTTCAATTTCTTGGACGCTGGGGCCTGGGGAGAGGCTATAACTCGCT TCTTTAGGTTGAGACTTTCTGTTACTGTCTCTCCCGCCGGAGGCAGCTTGCCTGGCTCCA ACTGGCGCTCTGGGGAGCTAGGTGCCTGGACCGTCAGCTCCTGTGCTGGCTGAGAGGGCT CGGGACCCGGTGCTTGCTGGCCCGGGCAAGGCTCGGGGGATCCTGGGATCACCTCCTCTT TAGCGTGGGCCGCCTCAGAGTCCAGTTCTCCCTGTGGGGGAGGTAATTTGGATGGCTGCT CTCGTTGCGGGGATTCCGGGCTCGACTCTGTCTGTCCTGCAGGTGACTCCAGGCCCAGAT CTTGATGAGGTTGAAGGGACCCGGGGTGAGGCTCTGGCTGCCTTTGTGGGGACCCATCGT CTGCATCCTGTCTAGGACCGGGTGATCCGGGGCTCGCCTCTGGCTGAGGTCCGGGAGACG GAAGGCTCAGTGGTGGACAGGGCGATCCGGGGCTCGTCTCTGGCTGAGGTCCGGGAGACG GAAGGCTCAGTGGTGGACAGGGCGATCCGGGGCTCGTCTCCGGCTGAGGTCCGGGAGACG GAAGGCTCAGTGGTGGACAGGGCGATCCGGGGCTCGTCTCCGGCTGAGGTCCGGGAGACG GAAGGCTCAGTGGTGGACAGGGCGATCCGGGGCTCGTCTCCGGCTGAGGTCCGGGAGACG GAAGGCTCAGTGGTGGAACTCTCGTAGACTTGAGCTCTCCTGTTTCTTCTGAGTTCGACT TGAAATCTACAAGAGCCCGTTTCGCCCGAGAGACTTCGGGGACAGGAAGGTTTTCTGGAG ACAGAGGTTTTAGGCCTTCCAGCCGCCGGCTGCGCCTCAGCGGCGTATCCATGGCTCACG TGTAGCCTCTGTAGCCTTCGGAACTGTCGGCGCCTTCATATGACGTCAGACTCGTCCATT TCCGTACCGGGCAGGAAGCGCACTTGCGGTAGAGAGACCCGTGGGTAGGCGGAGCCGGGG ATGAAGTCGGTCCCGGGAGGCTGGGCTTAGTAGACGCATGCGTGTTGTGCATGAGCTCAG TTACAGAGTTTAGTTGCTTGGTTTCTGCGATGCGTTTTTTGCAAACTGCGAGTTCTTGCA AGGGGATGGGGTGGGGGTATATTATACATACACACACACACACACACACACACACACACA CACACACACACACACACATATAAAAATAATTTTTTTTTTCTTGAGAGAAGAGGTTGGAAA AAGGCGGAGGGAGTTTGTAGGCAGAGCCGAATCAGCGCGCTAACTTGTTCTGGAACTGCT GGGCCCGCAAACATCGCCTTTTCTTTTATCTTTTGTAGCACAGTAGCTTTGCGCTGTGTA ACAAAGGGGAAGGTCCTGGTGGTCTTCCTGAGTGGGAAATCTTCAGTTTTTGAGTTGTCT CAAACGTTCCCATTCTTTTCACTTCCTCTTCTCTACTAGTGGGCCCAAGTATGCAATAGG TGGTTCTCATCTTTGAACAGTTTCAGTTAATCAGCAAAGTGTCAGGTCTGTGGCCCAGAA AACCTTGACTGCTTGTTGTCAATGTTGGGGGTTCACAACCTGTGCCCGAAGTCAGGTCTA GCTACCTTATCCTCAATAAGCCAATTGAAAGAGACACATTAAAAACTGGAAATCTTTAGA AAAAGGAGATTTATTCAATGTAGTCATACTAGAAAGAGGGGCAAAGAGATTCTGTGAATC ACCCAAATTTGACCTCAGGGTTCTAAATTTAGATAAAAAATTTAGATAGAGGGCCAAGGA TAAATACATCTGAGTAGTCCTTACCAAGGTATGACTCTGCCCACCATTGGCCCATTATTA TCTGGGTTTTAGTCTCATCCTGTAAGGTGGTCTGACAAGCTTTTAGAACTCTGAAATCTT TTTCCAGGAGACAAGTTTCCCCTCTGGCTGGTACCTTTTTCTTCTCCCAGCATGAGAATT CTGGGGAAATTTTCATTTCTTTGGAGTCCTCTGTCTGATTGATTGGCTGATAGGCTAAGA GATGCAGTGTCGAAAGCCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGCAGATTTCTG AGATCGAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAGAGAA ACCCTGTCTCGAAAAACAAAACAAAACAAAACAAAACAAAACAAAACAAAACAATTAAAA CCTTCATCTCTGCCGGGATGGTTACTTGCTGATCCAGGAGGAGGCAGGGAAGATGAAGAC CCAGAGAAACGTTCCTGTGAGCAAGGTAGAAAGCACAATTCTTGGACACACTCCCTAGGC ACTGCCACACATGGAGTCAACCTGAGTCCATTCTTAGGGGTAGGGAATAGTACAGCTTCT ACATGTCACTAGAAACTGTAGCACTCGTGTGCTGTAATTATATGTCTGGTATGGGCTGGT ATGTCTGGTATGGTATATCTCCCCGGTATGGGCTCAGAGCCCGCATGTTCCTGATTTAAG GGGAGCTAAGGAGTTGTAGTTAGGCACCAAATCTCAGCCTCTCAGTTCTCAGAGGAGTAG GTTCTGTTTGGTTGCTTAAATTCCTGCCCCTGCTTGACATAGGGCTCTGGAGGAGATTAT ATGCCTTCCTGCACTCCTGCTCCAGGCTGCCACCCAGCCCCCTTCCTGGCTCTTACCACT GCCTGGAGGGATCATTCTCAAATGTTGACAAATGTTGATCAGAGAGCATAACTCAGGTCT AATTTTGTGTCTCTTCCAGGGTAGTAGTGTGTGTAAGAGAGATCGATTTTGGACAGAAGA CTTTTGATCTGCCTCTATTACCTGTGCAACGTTCCACTTGAACCCAGCCTGCCTTTATCA TTGCATGCACAGGTCAGAGAAGGCTCCTGAAATTTTCATAGTAGATAGCTTCCTTCCTCA GTTTCATCTTGTAGGAGGATAAGAAGGGGCTTTTGTTCCCCTCCCGCCATGAGACCTCAG CAGGGGTCAGCCCAGGCAGGCTCTTGTGAAGGTAACCTGGTAATTCACTCGCCCTCACTT TGCCCTGGCTCACTTTCCCATTCACTTATTGTTGTTTCTAGGGAAGGGGGGGGGGCACTT TGTAAACATTATTTGCATATAAATCCTCATTTTAAGAGTTGGCTCTTGGTAGCTTTCAAA AGCTCTCCAGGATCTTGAAGCTCCTGGCAAAACAGTGAGATGTGGAGTACTAATAAAGGT CTGTCTGTTTCTTTGTGTATGTCTATCTGGGCTTGTCTTTCAAGCTCCCAGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTCTGTCTGTCTGTCTGTCT GTCTGTCTTATCTGTGGGTATTTACCTCTGCCTGGGCAAGGTAAGAGAGTACCTGGCTGA CTGTCCTTGTCTCTTGATTCAAGCATGCATACCACTGTGTGCTCTTGCTTGTATAAATTT CATGGGCCCATCTATGTGTGTGTCTGTGCGCCTCTGTGTGTGCATCTGTCAAGGCAGACC ATTGTACTAGGGCTGACAACCATCCTCCTGGCTTGGTATTCCAGGGCACTAAAGGAACTC CAGGCGACCCCTGGTAGGCAGCAAGTGTTATAGTCAGTGCTGGGGATTTAAAAACTCAAC CGTGCTGCCCTGATAGGGTGAATGACTGAAGCCCAGAGGAGTATCTGATTCATATCATGG ACCCATCTGTAGGCACTGGTTTCCTTCAGTCAGCAGATCTTAGGTTACATAAATAAACCA GGTCTTGCCCAGTCAGCACTTCAAGGCATGTGTGAAACTCAGCCCCTCCAGTGCATAGAC CAGGGGCAGTCAGGGACAGGAATGTCTGCAGGAGGGGCAGTTGCCAGGCAACTAAACCTT CCATCTCTGTGACTAATCCTGGTTCACAGTGCCACTCACTGCCTGGCATTGGCCAGCTGC TTTATCCTTTCTGTGTCTTGGTTATCTTCTGGGGAACAGCAAGGTTTACTATGAAAAGCT GAGGCTTCAGAGTCAGACTGGCCAGGCTCCACTCCCACCTCTACTTATTTGCTGCGTGAT CGTTACCAGTACCCAAGCCTCTCTGTGCTTCAGTTTCTTTATTAATAAAATGAGTCATAA GAACAGCACAACTGCCTCCCAGGGTTGTGCAGAATAAACGGCGCTGCACGGTACATATCC GGCAGCTGGCTTCTCTCTGCTACTCACAGTTGCTTATGTACTCAAAGACAGCTTTCCTAT AGCTTTTCTAGAATCCTCTTTTAGTCAGGCTGAAATCTCCCATCTCTCCAACTGTCCCCC AGTTCTCCCACCCCCTCCCCCAGAGCTGACTGCACGCAGCACCGTGGGTCCATCATCTTT CTACTCCACAGTTCCCAGTAGTATGGCCAGCTCCCCATGCTCTTCCTGGCAGTAAGACAG CAAGCGGGCCTCCAGCGGAAACCGTCCAAGGAGCTCCAGCTGTCTCCTGGTGTTATTTTT GGATACTGTAAGTTCCCCTCCCCTCCCCCCTCCCCTCTCCTCTTCTCCCCTTCCCTTCTT TCTCACTGTTCCTGCTTTCACCTTCTCTATTTTTCTCCTTCCTTCTCCCCCCTCTGTGAA GCCATCTTGGTTAGCCTTGAACTCATGGCAATCCACCTATCTCATCTTCCTCCTGAGTAG GTGCTACAGATGTGAGCCATCATGCTTGGCTAGTACAGAACCTCTGTTGAGTTGTGTTGG GGTCTAGTCCCTCTAATGTAACCCTTGGGTCTGCCTCCTGTTTGGCAAGTGTGCACAGCT ATTTTCAGGTGTATGTCCCGAGTTGGTTCCACAGAGTACATGGAGCAGGACAGGGGCCTG CTCTTACTGAGAGCGCTCATCTCAGACCCTGTCCCTTCGATCCATGAAATGCCAGGACAC GAGTGGGGAAGGAGGGACTGAGTGGGAGGAGAAGCACTGGACCATTCAGTTGTGGCACTC ACAGAGATCTGGGAAGCTGCTGGGTTGGGGTCACTCCAAAGCTCTCTGGTACCTGCTGCT CAGGGTGGAGAAAACAGCTTATCTCCAGATCTTCTCAAAGCATCTGTAGGTTTTGCTAAA ACAAGAAGGGGTGCTGCTGCAGTTCCTTGGTCTGCAGAGGGTAGAGAATCTTGTATGTGT ATGGGTGTGTGTGTGTGGAGTCTTTAAGCATGCTCCCTGATCTGCACAGGTCAGAGAAGG GGTTAGAAGTGACCTGAGCAGGTGGAAGAACGGAATCTAAGAAGATGGATATGAAATATG GATATTTGAATAACATGGATATTTTATATCCATCCCATTCTCTCCCTACTGTATCTGACA ACAGTGTTTCTTCAGCTTCAGAAAGAATCAGTCAAACTGAAGGTGTGTCCAAGCCTTAGA TGTTAGGATTCTGTATGTTTGGTATGGGGCCATGGGCTTGGGTTTCTAGCAAACTCTCAG GTGCTGCTGCTGGTGTTAGTGATGCAGTTAGTGTGGTGGTGCTGGTGCTGGTGGTCCACA GACCATACCCCGAGGATCAGTGTACCAGAGAAAGGGGTGAAGGAACCCCTGAAGAGCCTG CCTCCTTTGCCTTCCACACAGTGCAGAGGTTGAATTCAATAACACCCTATCATTCACCAA GAGCTGATTATTTCCCCTGTGCCCGATACTAGAAACAACCAGGGGAACAGTTAGTCATGG TCCCTGCCTCGGAGCAACTTACATCACTTTGGAGGTTCCTTTGGAGAACACAATCTAAAA GCCGTGAGGTCCTTTGAGCAGGAATGAGTTTCACCAATGAACAGGGGAGGTAATGGCATC TCAGAGAGGCCATAAGGCTTGCTCAAAGTCCACTCAAATGTGACTTTAACTCAGACCCCT CAGCTTGAGATCTCGCCCCATCACCTGATTGGGATGGGTGAGAGCTACCAGCAGAAGTGC GTGGGACTGGGCTTGAATGGAACAGTGACAGACCCTGTACACTGAGGTACCCTGTTACCA GAGGGTGTCATCTGGGGCTTGTGTGTAAAAGGAGCTCATCAGAAAGATGGGTAAATGCGT CCTGGCGTTGTACACACTAAGTTCTCAGGATCTGGTCAATGACAGAGTCTCAGACTAAGT CACTACCCTCCTCTCCCTCCTTTTGTTTACTAGCCTACTGTCTTAGTCAGGGTTTGTATT CCTGCACAAACATCATGACCAAGAAGCAAGTTGGGGAGGAAAGGGTTTATTCGGCTTACA TTTCCATACTGCTGTTCATCACCAAGGAAGCCAGGACTGGAACTCAAGCAGGTCAGGAAG CAGGAGCTGATGCAGAGGCCATGGAGGGATGTTCTTTACTGGCTTGCCTCCCCTGGCTTG CTCAGCCTGCTCTCTTATAAAACCCAAGACTACCAGCCAGGGATGGTCTCACCCACAAGG GGCCTTTCCCCCTTGATCACTAATTGAGAAAATGCCTTACAGTTGGATCTCATGGAGGCA TTTCCTCAACAGAAGCTCCTTTCTCTGTGATAACTCCAGCTGTGTCAAGTTGACACAAAA TTAGCCAGTACAATTGACCCCTTGTCAACTTGACACACAAAAACATCACTAGTAAGCCTC AACCCTTACAATCTTATTCATCCCCAAGATCTAAATAACTTTAAAAGTCCCACAGCCTTT ACATATTCTTAAAATTTCAATCTCTTTAAAATATCCATCTCTTTTAAAATCCAAAGTCTT TTTACAATTAAAAGTCTCTTAACTGTGGGCTCCACTAAAACAGTTTCTTCCTTCAAGAGG GAAAATATCAGGGCACAGTCACAATCAAAAGCAAAAGTCAATCTCCAACCGTCCAATGTC TGGGATCCAACTCACGATCTTCTGGGCTCCTCCAAGGGCTTGGGTAACTTCTCCAGCCAG GCCCTTTGTAGCACACGCATCGTCCTCTAGGCTCCAGATGCCTGTACCCCACTGCTGCTG CTGCTCTTGGTGGTCATCTCATGGTACTGGCATCTCCAAAACACTGCATGACCCCTTCAG TCCTGGGCCTTCAATTGCAACTGAGGCTGCACCTTCACCAATGGCCTTCCATGGCCTCTC ACAGTACCGAACCTCAGCTGCTTTGCGTGACCCCTTCATGCCTTCAAAACCAGTACCACC TGGGTGACCCTTACATATTACCAAGTCCCACTGCAGCAGGAGTACATCCTTGGCCATCTC TGGAACACTGCCTCTTTGTGCTTTCAGAAAACACTTCCCAGAAGATGTCACCTCAATGAT GCTGGTCTCTTCTTAATCACCGCTAATTTCTTAGCTCCAGCTAACCAGCATCAATAGTCC CAGTAATGCAAAGTTTTTGCTTGGTAGTTCTGGTATCTTGTTAATCACAGCTGATTCTTC AGCCCCAGCTAACCAGAACTACAGAATCTTCACAAACAAAACAGCAATGGCCCTGAAAAG AGTCTTTAATTTTCCCTCTGAAATTTCACAAACCAGAGCTCCATCTTCTGCAGTGTTCTC AACATTATCTTCCAAGCTCCTACATGACATCCGACAGAGCTCTTAACAACGGATGGATCT TCAAGCCCAAAGTTCCAAAGTCCTTCCACAGTCCTCCCCAAAACATGGTCAGATTGTCAC AGGAATACCCCACTCTGCTGGTACCAATTTGTCTTAGTCAGGGTTTGTATTCCTGCACAA ACATCATGACCAAGAAGCAAGTTGGGGAGGAAAGGGTTTATTCGGCTTACATTTCCATAC TGCTGTTCATCACCAAGGAAGCCAGGACTGGAACTCAAGCAGGTCAGGAAGCAGGAGCTG ATGCAGAGGCCATGGAGGGATGTTCTTTACTGGCTTGCCTCCCCTGGCTTGCTCAGCCTG CTCTCTTATAAAACCCAAGACTACCAGCCAGGGATGGTCTCACCCACAAGGGGCCTTTCC CCCTTGATCACTAATTGAGAAAATGCCTTACAGTTGGATCTCATGGAGGCATTTCCTCAA CAGAAGCTCCTTTCTCTGTGATAACTCCAGCTGTGTCAAGTTGACACAAAATTAGCCAGT ACACCTACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC TCTCTCTCTTTTGTTTTTTTTGAGACAGCGTTTCTCTGTGTAGCCCTGGCTGTCCTGGAA CTCACTCTGTAGACCAGGCTGGCCTCGAACTAAGAAATCTGCCTGCCTCTGCCTCCCGAG TGCTGGGATTAAAGGTGTGCGCCACCATGCCCGGCACTAGCCTACTCTTATTTCCTTCAC ATCTGGCTTCTTGACAGCTCTGTTTTCCTTACAGTGTGATATCTACTTCAGTGGTGGTTG TCCCTCTCAGTCAGTGTGGTGGCTCGTCTCCACAACAACCCTTGGAAATGCTGTCTTTCT GTGATGCTTGGGATGGTGCCCAGGGTTCCACACATGTTAAACAAGGATTGTAACATGGAG CCATACCCCCAGCCTTTGGAGATATTGACTTGGTGACGAAGAAAGAGCACCCCAGAGCAA AGTATGAGGTTCCTTTCCTGAACCACAGATTAAACTGGTCCCTGGTTTAGTGGTGGGGAA TCTCAGTTCTTCATTGCAGTAGTTGAAGACCAGCTCCAGACCTCAGCCAGATGGCACATC CAACCTCAGGTGAGTGAATCGGGTCTCTCTGAGTCAACAAACTATTTTCTGTTTCTTTGG CGCCTCCAAATGTCTAATGTTACCCTAGGACCAGGGCTGCCTGTGGGACTCACAGGATCA CTGGGCATGGCCTGAGCTCACCGCCATCCTATTGTTTAGTTACATCAAGAACCGTTTGTC TTGTGATCATAAATCTGCATCTCAGATACTCTGACTCACTCTACCGAAGGGGAGTCATAG AAACAGATTGTTTCCTCCGCAAACACCATTTATCTGCAGGTTAAAAGGCGTGCTGCTAAC AGGATGGTTAGCAATATTGATCATGCATTTTGCAGCAGGAGATTAGGAAGTCATAAACAT GTTTAGGTTTCGCCGGTAGTTTAAGCCATCAAGATTCTGTCCAGAGTAGCTAGCACACAA GGGTGGTGCTTGCAGATCTTGTCTGAGTCTCCAGCTAATCTTTTTCTTCAGAGGTGCAGG GATGAAAGCTGGTCACTGGCCAGAGGGTTTGAATCCAGAGCTCTGCTTCAAGAACACTAG TGATTTTTACCCACACCTTTGTGTACTTTATCTAAAGCATGAGTAAGTTCCCACTGTAGC CTAGGCTGACCCTGTTCTTTCTAAATAAGCCAGAAGCTGCAGGTCTTTAAAAGTGCCTCT CATCTGGGTGTGGTGGTACACACCTGCAGTCCCAGCACTCAGGAGGTGGGAACACTAAGC GGACCAGGAGGTGGAGATCAGCTTGGATATAAAACAAAATAAGTTAATTAAAATAAATCA AAATAATTAAGACAAAACTAAAGAGGGCTTCTTATAGCGATAAAGCACAGATTAATCAGA GTGATATTTTCTGTTCTGCGCATCTCAACATAAAACAACACTCAGATGCTGTCCTCTTCT GCTCGTGTGGTTTCGGCTCTCTGCTTTTGAAATGACTCTGCATACATCTAGATAGACTTT CTTGGAGAGGTGTTAAGTACTGGGATTTCCAAAGCTGGCCTGAGTATGGTCTCCCCTCCA TGTGATCTTCTTACTGTGTCGCCTGGACACCCCTCAGGTACTGGGATCTATGTCCCTCTT CTTCAGACTCCAGGATAACCCCCAGCTAATGGAATGCAACATTAGCATTTCTAAGGTTAG ATCATGGAGGGCTGAGTACTTCTGCTTGGCTCTCATGGGGTGCTGGCTCTTGGAACTTTC AGCCTCCATGTTGTGAGGAAGTACAAGTCACCCTATGTGGAGAGATCGCCTGGAGCTGTC TTTGGTAGCCCAGCCAAGCTGCTGACACCCTTATCATCTAGCAGGTAGGAAAGGAGCTGC ATCTGTGGTGATTCTATCCCCAGTTCACCAGGCAATCCTGACTTTGAGCCTGGCACCAAC GGAGGTCCCAGAAACCATGAAACAGAGATACATTCTCCCTGTCCATATCTGTCCTGCCAA ACTCATCCACAGTTATTTTTATACCACTAAGTCTTGGGATGGCTTGTTAAACAACAGCAA TTGCCATCAGTTGGCTGGAGTAAAAAGAACCAGATTTGTTTGAAGGAATCTCACCAGGTA TATTAACCACACTATAGGACAGTCCCCATGTCCAGGAGTAGCTGGCCAACAAAAACCAAG CCAAACTGAGTAGTATTTCTGTAGACTTTTCCCTCTCATTTTGCTTTGTTAGGGATTTCT TTTTGTATTATTGTTTTGTTTTGCCTCTTTTGACTTCTGTTTTTGTAGGTGTGTGTGTGG TTTGAGGGAGGGAGGGAAAGAGGGAGGGAGGGAGAGAGGGAGGGAGAGAGAGAGAGAAGG AAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAACAACAACAACAACAACAACAACAACAAC AACAACAACATAGGGTTGGATGGGTAGGGAGGTGGGAAGGATCTGGGAGCAACTGGGAGA GGAGAAAAATATGATCTGAGTATATTGAATGAAAAACAAATTTTTCAATAAAAAAAATTA ATTATCCATTTGGGAAGATCAAGTGCCCGAGAAAGGGACAGCAACAGCTTTATTCCTTTG GGATGGGAGAGGCATAAGACTGGAAGCCTTTTAAGGGGATGTCAGCTTGGGTATTATACA GGGCCCTGAGTCCTTTCCTCTCTCGCATTGGCCCTGCTTAGATCCCTGCCCTTGTGCCTT CCCACTTCTCTTCAGTGAGCAAGAAGCTGTCACCTCATAGAGCCTGCCTTTGGTTTCTCT AACCCCCTTCAAGTCCCTGGCATTTGCAGTTTCTCTCTCTCCCCGGAGGTCTGTAAGGCT TGCAAGGTTTCTAGAAGATGATTGCTTAAGAGCTTGAGGTACTTCAGTGTTCCTCAAACC TAACCAGGCAGCTTGCAGCCTTGTCACAATGCAAACAGTTTCAGTACTCTGGGAAGGGGC CGAGTAGCATTTCTTTCAAGCTCATGGGGATGCCAAAGCCACTGTTCCCTGGACAGACCT TGGAGAAGGCAGCAGCCACTCTCTTGAGCAAGCACTGGATCACTGGGCAGCGCTCCCACC TTCTTAATCTCTGTGAATTTTGTTCTCTTGCTGTGTGTAAGAGAAACACTTGTCTCTAAC CGGAGACAACAGCAACAATGCAAAGAATGTTCCCAACAAGTGCAGCTTGATGGCCAAGGT GTTTATTAGCTGTAACACACAGACATGCTGCGTTCACACGAAAAGGTCAAAGCCTCTCAC CTGTTAGTGTCTATTTTACAGGGCTCCAGGGCTACTGAATGATCAATGCAAATCCTGACT TAGAGTGCCACCTAGTGTCAGAAAGTAGAAAGAACTACAGGTCAGAGAAACTGCCCAAAT CAAATTCAGAAATTCATTCTCATGTGCACTGGGCCCTCCCCCCCGCTGAGCAATTATTAT TACATTAGTAGCGGTGCCTCCCTGGGCAAGTTGCTCGGCCTGCCTGAGGGTGAACAGGGG AGGGCAAGATTGGACAGGCAAGAAGCCTCGCATTGCCAGGCCTTGGGCTTGTCCTCGAGC TGATTGACGAGCCAGCAAGCGGTGCAGGTAACTTAACGTCTAGGCAGTCTCCAGATTTTC CACCGAATAGACCCAGTCAAAACGATCCCTAAAGTACCACCTGGGCGCCCAGGCCTCATC CGAGTGTAGGGATTCTCAATGCTGGAATATGTGTGTTTGTTATGAGGGCCTGTCCTGTGT TCAGAGGAGTGGTCAGATGTGTGGCTGGCTCTTCTCTGTTAGAACCCAGACCTGTCCAGC TACAGTCTCTCGCCTCCCTCGGCTGCCATAAAGAGCTAACAGCCCACACCAAGTACAACC AGGCTGGCGGAAATGAAGATATCCTGAGGAGAAAATGCGGGTTTCTCCAGCCGACTCTCA GACTATTCAAACAATGGACTCCAAGAAGTGGGATTTCCCTGGGAGTCTCAATCTGGGAGA AGGAAAAGACTCCAGCAGCGGGGAGGGTACTTGTTTCCTAGAAATGAGATTTTACCCTTA AAAGTTTGATTCCCCCCCCCCCCCCTTAAAGATAGGTTCTCGGGGCTAGAGAGATGGCTC AGCTGTTAAGAGCACTGACTGCTCTTCTGAAGATCCTGAGTTCAAATCCCAGCAACCATA TGGTGGCTCACTACCATCCATAATGACATCTGATGCCCTCCTCTGGGGTATCTGGAGACA GCTACAGTGTACTTGCATATAATACGTAAATAAATCTTAAAAAAAAAATAGGTTCTCACT ATGTATCCTGGAACTCACTCTATAGACCAGGCTGGTCTTAAATTCACAAAGACCAGCCTG CCTCTGCCTCTATGCCTGTCTTTGTGTGTGTGTGTGTGTGTGTGCACATATTTCTAATAA CTTTTCAGGTCACTTTGTGTAGACACTGGTGTGTCGGAGGTGGACTGGATCACACCTTGA CTGGCTGCTTAGATGTGTGTATCTGTCCTGGAGATGCACTGGGGAAGGGGGATGTCAATG GATTTTTGTTCCTCTTCCCAATGTGGCCACATTGAATAAATCCCCCTTTTCTGCTTTTTA CTTCTAATTTGGATGTTTTAGTGGGCTTTTCAAGTGGCTGGGGAGTTGGCTCAGTGGTTG AGAGCACTTGGTGCTCTTGTAGAGGACTCAGGTTCTGTCCCCAGCTCCTGCATGCACAGT TCACATATGCACACACACCTTACACGTCTGGCTCTTACATATTTCTTCTGTTCTATGTTC CCAAGACTCCAGGAATCCAGTCCTGGCATTTTTGCGCTTACTTTTTTTGTTGTTGCTTGT TTTTTGTTTAGACAGGGTCTCACTATATAGCCTTGGCTAGGCTACAACCCCCTATGTAGA CCAGGTTGGCCTCAAACTCACAGCCATCTGCCTGCCTCCGCTTCCCAAGTGCTGAGATCA GAGGTGTGCACTATCACATCCAGCCTCTTGCACCCTGCAGAGCTTCCCCTGCGGAGCCGC TCACCTCTGCTTCAGAAGTGGCCATGGATCCACTGAAGCTCTGCACCCTGCTTCTGGCAC CATGGGTCTCATTGTGTACCCCTCACAGAGTGTCATCTCTATCTGCATCCACAACCCTTT CCCCTGAACCCTTGAGGACTAAGAGAGGATGCTGACACCCCTGCTCAGCTGCTTCCAACA TACACGAGCCAGCACGATTGACACAACTCACAAAAGAAAGGATGTTTGGTTATAGCAGAC ATGTGAAAGGACCTGTGATGATGGAGTATAAATCTGACCTCAGACAGTGGGAGACGAGCA CTGAGCATGGGTTTGGTTTGCTCTATCTCATCTTTGCTAAAGACATGCATGTTTTGGTTC GCTTTACATAGTGCTGTTGAGCTCAACTTGTGATAACGCCACCATTGAGAGAAACTCACC CAAGAACTACTCATGAGGTTACTACAGCAGACTTCCGTAGCCTCACCTCAGGCCAGTTGG CGAGCCTGGCGGTTTCTTCAGAATTGAGCTACAGCTGCCTGGTGTCTGCCTACCTAGAGG ACTGGTCTGCAGCTGTTGAATCATATTTGATGTTTGCTAAGGGACTGAATTGCTGAGAAA GAAGATCGATCTTACCCCCCAAAGAACTATTGCTGAACAGGTCCACTTCCCCCACATCCT AATAACTTTTCTCTTCCACTACCTCTAGTGGGTGGTGGGTTACAGGAGAGAACGAACCCT TATTAAAAATAAGTTGTAAAAAACGTATGCCTATACTGGACAGTTAGACCTGTAGGCATC CCTTGATGCCTTCATGGGAGAGGCCTCTTGGCTCCTCCATTCCACTCCACTCCTCTCTGT TCCCATCACACTCTCAGGACACCCCGGTTTCTTTTCATAGTGGTTATGCATTTATTTGTG CAAGTCACGCCTGTGTCATCACCGGAGTCCAGCCAATGGGAGGCAGGGAAGGACTTGGCA TTGCAGGAACTCAGTCTTTATCTGTGGGACAAGGGGATAACCATTAGGCCTCCATGACCT GCCTCGGTGCTAAAGTACACAGTTTGATGAGACTGGAAAGTAGAATTCCAAGTTCAAGCA AATGAGGTCAGAGTTCAAATCCACATCTTTTCTATAAACTGAGTCAGGTGAAGAGATCTA CTTTGCTTGTTTCCCAGCTAGGAAAACCCTCTACCAACTGAACTACAAGCCCTTAGGATG CACATGTAGATGAACTCGTGTCATTTACAGTTCAATGATGTTTAGAATCAAATAGATGCA GGGACACTTGGCAGTCAATAGCCAGGACTGAGCTCTCCCTGGACCCAGATTCCCAAGCCC TTGTTGTGTGGGTAGGCAGGCTGCTGGAAGAACAGGGTTCACTTGAACTAAGAGGGCTGA TGATGCTGGTATTTGAATGTCGCACCTCCCCTCCCTTGTGAAATATTCCTTCTGGAGATC CAGGGCCATGCCACGACCACCTGTGCACCCTCAGTGGGGCAGGAATTCAGCTCGGGGCTA CACTAGCACTTACTGGGAAAGTCTAGTAGTCTTAGACTACTTTCTCAAGGTCCTTGGGCC CGTGTGAAGCAGAGCTTGATGGAAGGAGTCAGAGGCCAGCAGCAGTCCAGAGCTGGTGGC CAAGGCTCTGCCAGTATCAGAGGAGGAGTGTCCTGGTAAAGGAAGAGCCTGGGTTATGGC TCAGTGGCAGTGTGTGCTTGGGTGTTAGGGAATCTCGTGGTAGCTTAGGGAGGCCGCAGC AGGTTGAGGGTGAGCTGTGAGCAGCAGGTGAGGTCATGCTAGAGGGCCAAGACTCTGGTG ATACTTGGTCTTACCTTGTTTGTTATTTTGGGGGCTTACTTTGGTTACAAAAGATTTTAT TGCTAAACAGAGATCCATTATAATAATATAAGGAACAAATTAACTTTAAGAATTGGAAGG AATCCAGTGTGGCTCACAAATAAGCCAGCCTGGCCAGTGAACTCTGATCACTGAAGGTTG GGAAGCAAGGAAGGCAGGGCCTTTCCTCGACTTTCTCACCAGCATGAGTAGGTCTAGAAT TCCCAGGCTAGAATTTCTTCTTGAACTCTACTTCTAATCTCAGGTTTCTGAGCTTTCAGG AGCCTCTGCGTCATGGCTGTCACTTCTCCTCCATTTACAGACGGAGACACTTGAGGCCCC AGAGACAGAGACCCTGTGTGGTTTTTGGTTTGATGTTCCTCTGGCTGGTTTTGGGAAATC CAGCATGACTGACTACCCTAGACATAGCTTATGCCATCCACTCTGGCCATGGGCAGCCAC TGTACACCTGCTGTGGGTGGGAGGCTGGGGTGTGCAGGGGTCACCTAAGAGCCATCCTGT AGGTGGGTAAGGAGGACATCCTGGTTCTATTCTGATCCAGTAGAGGAGGCTGGTATCTTA GGCACTGAGGTATCTGAGTCTGGGGTGGCCTAGGGGAGGGGACCACCACCCTTTCCTTGG TGTACTGTTTTAGAAACATCACTGTCCTTTTCCCAGGGGGAACTAGCCCCTGTCTAAGCC AGGGAGAAGGGGCCATGGTAACTTCCTTTCGAAGATCTGTGGAGCCCCGAATGGGAATCC CTTCGCCTCTTACTTTGCTCATGCTGTGTGTTACCTTGGGCCACATCTTTATAGGATGGT GGTGGCCCCAGCGATAGACCTTTAAGTTCCATAGGTGTGTCAGGAACGAAAGGGGTGTCA TCCTTGTCCTGCAAAAGAGAAGTCACTGTTCTTATTGGTCTAGTACATGGACGATCAGTT CTTTATGAGGTGTGTCTTGGCAGGGTCACTTTCAAAATCTCAAGCTCTACACGAGGTTTG ATGAGGGAACTTCTAGATGTCTACGTGTGACTGACTATCTTCCCAACACTGATTGAGAAA GATCCACAGGGGTCAGTAGGTGGGGTTTGAGTTCTAGTTCTGCTCCAGAGTCCTGTTGAC TGTGGCTCATCCCAACGTGGGCTGGTCTGCTCGAGCTTTAGGAGGTGGTGTGATTTCTCT AAGCCTTGGTTTACTTAACTGTGTCGTGGCAAGTACACACCTGCCTGAAAGAAGCTGAAA TAAAGCTATGTTTATCTGTGTCATTATATAACTATATGCAGATTCATGTAGTGCTCCACA GAGGACTCTATCTCCTAAGTGCTCAGCCTGTGATCATTGCCTGCTGTCTGTCCATTCTGA GCTCTCTGCTGTCTAATGTGTCTCCATGCCCTGAGGGTTTTGTCCACAGGAAGGCCTCAC CTCTGCTTGCAGGCGTTTCATCCTATAGGCTGTGATGGCTGTGGACCCCGACAGGAAGAT CTCCAGGAAGGTGAAGCAGAACAGGGTCAGCTCTAGCCTTTGGATGTAGGTCTGCAGGAA GAAGGATGGGTTACCTTGCTGAGAAACAGCAGGGCTTCTGCTCCCCTCAGAGTGTAGGGA GGGATTCTGAGGGATTGGGACAGTTTCCATTATGCCCTATGCCCAATGCTGGGCACATTC GGTGAATGCTTCCTGAAGCAGGAGGACCCGAGAGTCTCTCAAGCCCCTGGGGGAACTGGA AAAGGCCCTAAGGGTCATGGACAGCTCTACTCAGCGGATGGAGTTGCCTAGACCCTGTTT TATAGCAGGGTTGGGGACGGGTGAGTGGAAGCCACTGGGGCAAAGCTACTGACCACTCAC CCTGCAGGCTGTGATGGCTGTGGGCCCTGACAGGAGGATCTCCAGGAAGAGATCTACACT CACTAGGGAAACCCGTGTGCAAATGCAACTTGGGTCACTTTGGAACCTGACTGAGAGGCA CCCTAGAGTGGCAGTGTTTCCTCCTGTGGTGGAGGAGCAACGGTGCAGTGAGAGAGAACT GGGCTGGCTGTTGCAGACCAGGCTTTAAGCCTTCCCTGTATCCTGGACTTGCTGTACAGC CTCTGGTCACTAATTTATCCATTTTGAACCTCAGTGTTCACTCCCATAAAAGGGGGGCAG CAAAGAGGACTTAGCCTGTTCTGCAAGGCTGTTGGGAGGAGGTGCTTTAGCTATGGAACC AGGAGTTCTAGGGCATGGTCTGTCAGTGAATTGGCTGCTCAGTACCAGGCAGGACTTTCC CTCTCCCTGGGCCTCAATTTTCCCATGTGTAAAAGGAGGACTGGATATGGTGACTTCAAG CACAGTCCAGTTTCCTACTGTTGACTCCCGAGAAGGCCAGCCATGTTGCTTCCGCCATGC CTCCAGAGGGATGTGTATAGATTGTCAGTGCCTGGTTCCGGGACAAGTTTTCTGAGTAAT GATTGCTTCTTCTCAGCCAAGCTCAAGGCTGTTCCCTCCTTGGACTCAGAGGACCCGTGA GGGGAGGGGAACTCACTGTGGGTTCAGGGTATGGTCTCCAGATTGGCCATGGAAAAGGAC CCTCCAGGAAGAGGTCCTTGGCAATGACAAAGAAGCCGGCCAGTGCGCAGAACAAGCTGA TAACGTTGGCTATCACACAGAGAACCTTCTGCAAGCAGAGTTGAAATGTTAGAGCTGGTG GCCAAAGCTTAGCAATCCAGCTCAAGGCCTTCCTTCCAGGAAATTGGTTTGTGACACTTG CACCCCCATCTGGAGGCTCTGCCTGTCTTTTGAGCTCAAGGCTGCTAAGTGACACCAGGC CTTGGTTGCTGGGAAGGGCCCCGGAATGCTCATCCTCTGTCGGACACATTGGAAGGACCA AGAGCCGCTGTCAAGTGCAGGAGGCTTATACTAAAGAAGGATACATTACAACACACGCCC CAGTGACCATCCTACATCAGGTTCACCAGCTCTCAGAGTCTAACATCCAGAGGACCACAC AGAGAAGGGTAGGAAGAGCCTGAAAGGGCTCTGCCCCTTAATCCCCCAGGGTCTTCCTCC TCTCCACCTGTCCTGCTGGGACCTTGAAACAGGGCTTCCTGTCAGGCAGGTCTCTGCCAG GCATTTTCTGCCTCTGCTGGGTCACGTGCCCATTCTCTATGCCCCTCAAGAAGCTCAAGG ACATGGTAGGACTTAAACTCTAGACTAAAACTCCTGGGCTGCAGTGAGGAGACAGTGTAG GATGACTCCTCCAGACCACAGTTGATGGGGATAGAAGTTAACGCTAAGAGAGGGTGTGGG TTAGAGAAGGTGAGGACCCGAGGACTACCGAGAAGTGGTTTTAGGACCGGGGGAAGGGAT GCAGAGCCTGGTGGTCCTCAATTGCCATGTAATGAGTGAGTTCAAGACGTGCTAGATTTG CTCTGAGGAGCAATAGGTAGTTATGGAATAATAAAAAGGGGTCAGATGAGCATTGGCATT CCTCTCTCTGCTCTCTGATCCATTCAGATTCGAGCATGTAGCCTCCCGCTCCTGCTGCCA AGTCTTCCTTACTATGGTAGACTGTACCCTCTTAAACCGTAAGCCACTCTCTGTCAGGCT TGAAAAAGCAATTAATAAAGAAGCCAAGGTTTGTTCTAGATGGAGGGGTGGGCTCCTGAG AGGTCAGGAGCTCCAGGTGGGGCACCCCTTCTTCTCTGTCAACTCTAGTCAGTTCTCTGC ACCTGGTGCCTCTCAGATGCCTTCCTCTATCCTGAAGATGCATTCCAGGTCACCCCTGTA AGATGCCCTTGTCCCCTCTCCCCCACCCCCCGGCTTTGAGAGAAGGATTTCAAGGTGCCA ACTCACCAGAGAGGTCTTAGGGAATGTCACTGTTGTCATGGCCGCCATCCCTGCAACGAG AAACTGCAGACCACATTTGGAGGTCAAAGGAGAGAACTTGAGGTGCCTTGAGACCACAAA GTCCCCTTCATTCTCTATGAAACAAAGCCCTGTTGGCTGGTGAGGTACAGAACACCAATT GGATTGAGCAAGCCCACTCCAGCCTCTGCCCCTCAATGTGCTTGCCCGTGGAGGACACAA ACCACCAGACTTCATGCAGGTCACAGCTAGGTCACAGTAACTACCCTCCCTCAACCTTGC TATTGCTCTAGGGAGGACATTGCTTCTGGCTCTGAGACCTAGGGTGTTTCTGACCTATTT TCTATATGTATGCTGAGTCCTTGATATGTGGCCATCCTAGGGAACATGGGGTGATAGGCA CTTCATGTGTAGGAAGATCTGTTACTGTAGTAGGAATGCCAAGCTGGGGCAGTGGGGATA GAGGACTGAGGGGAAGCTGGGAATGGGGGTGAAGACATTTGCCCAAGAGGACACTATGGA GCTGGGGCTGAGAGTGAAGGCAGTTTTCAGGGCTAGGATAGTGCCCTGGAGTCTCGGAGG AGTATGGATCCTCTGTTGAATAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTAT GTGTGTGTCCCATACTGTCTCTCATTCTGGCTGATGGCCCAGGAAGGACAGGGGTTGTGG ATTGCAGCTGTGTGTGGCTGCAGAAAGACCCTGATAGCGATGAAAGGCTTTGGCTACAAA AGGCTGGGTGCTCAGAAGCCTTGTGAACCTAGCTCATGCTGGTTCTTCTCTCTACCCAGC ATACATGGTCAATTAAAGGAGGGTCCACAGGTCCCATGAGTGACAGGCACTCTCAGGAAG GAGCTATGAATAGTGTAACTGAGGGAATGGAACATAGAGAGGGAAGATGGAGGCAGGTAG GCTTACTCTTTGTGCCTCTTGGCTGTGCTCAGCCTTCAGTGCCAGGGCCTCCCAGGGGCC CTGCGTACCCCTGTACCCACTGATTTGGGTTCTTACTCACAGAGACAGTTCCCCAGAGTG GATACCAGCACTTCAACACCACCAGGTGCAGATTCTTGACTGTGGAGATCAAGTAGCCAC CAAAGGCCAAGTGTGCAAAAGCAATGGCGATGTGAAAGCCCTGGGTGGGAAACCGGAAGT AGCTAAGGTGAGGTGGCAAATGGCTAGCCCTACATGACTAGCAGTGCCTGGACCTACTGG TGGGATTTCCTTTCCTTACTTCTCAGGGAGCTTGGTCATCAAGGAGGGACCCCCTCCCCA GGGCCCACTGGAGGGACAGGCAAGGATGTCAAAACCCCACTTGGGGCATGCATTGTGCTC TGTCTCTGCATGGCTGGCATCTTGGACCCTGTTCACACTCCACAAAGCCCCAGCCTCCCT GTTGCATAGATTTCAGTTTTAGGAGAAGTGTAACTGGGAGCTGGGGGCTCCCCACTTAAC CTCTTCCCTGGGTGTCACCTCCCTACTCACACCCAACTTCTGTAGAAGGTCACTTCCCTC CAGGGCTTTCTCAAGGTGCCCATCTGGAACCAGGTTTTGGGGCTGGGCTACTTTCTGTGC AGGCTGGGCAGGTCCTAGGTTCTGCCATCGTGAGACTTCTCCAGTAACACTGCCGGGAAC CGCTGTGGGAGCTTGGCCAGCCATTGACCCTGGCCGGGAACCCTGGCTGTAGACCAAGAA GAAGACCTTGTTAAAGTTGAGCTTGTGTCCAAGGATCAGATGCAACTCTTGCTGTCACCT CTGCCCCGCGGACAGTGATGGCCTTGTCCAGTAGCTTTTGACCTTGATTTGTTTTCAGAT GGTAAAGCAAGGCTTTCTATTATCGGTGAGGAAACACACACATATAACAAGCACAGACAG AGAAAAAGGCTCCCTGCAAAGCCAAGTGGAGACTCAGAAAGTAGAAGCCCATTGACTTTG ATTTAAATGATCTTGAGTCTATCAATGTTCTCAGCCTCTCTGGGGCTGCAGGGAAATCAA GACCAGATGAACTTCATGCCCAGCTAGTACAAGAGGGAGCTTCCACTGGCTGCCTGGAAG GTAAGCAGGAGCTAGGGGTCAAGAGGCCTGGCTCATGTGAGCATTTTGTGAACAGTTCCC AACCTGTGGCTTAGAATGAGACAATTGAAGGTAATGAGAACCAAACCATGACCTTTCGAT GATGCCCATGCCTTCTGGGTTTGAGGAGATAGGAGAGAGAAGGGAAGGAGATTTCTGTTC AGGGCTTACTCTGAGCCCACATGGAGCCAGAGAGTCAGTACTTAACAATGTCTGCAACAC CAACACTCATGAGTCCTTTCTCTGTTCCAAGCACTCATACAAGCATTTTATATGTATCAT CTGTTGGTATCTGCATGCCAGCCCTACAAGGGGAATGATGTTTTCCCATTTTGCAGATGA GCCTCAGAGAAGCTAAATCACACATCGAAGGTTGCACAGCCAATAAATGGGAGTGGAAGA ATGGTAAGCTGGTCTGATCCCATCTCCTGTGTTCTTGGCCTGGACTGCTGGGACCCCCTG GTCGATATCTCCATTAACTGGCACTGACAGCCCTTGGTTTAGTGGGAAGGACGAGAGAGC ATTTTCTTCCTTGGGCTTTGGAAGCGGAACCCAGAGAGATGGCTGTGTGGCTCTTCTGTT AGCTGATCTGGGAATGTTCGGCTCTAAGGCTCTAATGGCGTAACTTTCCCCAGGTCTTTC TGATGTAACTATGACTTCAAGTGAAGCTTCTTGGGGGCAGAGCTGGGATGGCCTGTGGTG GTTAGTGGTGGTGGCCATGTGGTCACTGGAGATGGGGAGGTGTCTACACCTGGGAGCTTG CTTCTGTAAGCTGTGGCAGTGGAAATGGTTCAAATATCCAATAAAGAGTTGGACTCAAGA GTACCCTTTCCCAAAGCACATCGCATGGAACATTGGTCCTACATTAAAAGGGACCATGGT TAAACAAGTTTAGGAAACCTTACACATTACCTTCTTACTTTTTCAAGGCTTTGAGGACTC CTGAAGGGATGTGTTCTGTTCTGATATTATGGACACTTCCTACATTTAGTTTGCTGTAGA ATCTTCTTCCTTAGAGTCCAGCCATATATGCCAGTTGATATTCTGTAGGGTTTGCTTTGG GTTTAATGACAAACTTCCAAACCTCTGGTTAGGAATTTTGGGGTATCTGCTCCCCACTGT TTAGTGGGGCTTGGGATTGGGCTCTGATCTCAAGGCTTATTTCCAACTTGAAATTGGAAT GGAATCATGCTAAAAGGAACTTTGTATACTCTTAAGGGGGTGGGGCCTGAGGGGGCAGAC CTTAGACACCAGAGGGAAAAGGGTGTGGGTTATAAAGTCCCTTGCCACGTCCCAAAATCA AGAGTGTAATGGCAGTAGGCCATTGCCAACAGTGACTCTCTCTTGCTGTAGCCAATGGTG ACTTTATCTTGCTGCTAACTATGGTGACTCTGTCCTGTCATTTTTTTTTTTCCCGATTTC CATTGCCTGGCTCTAGCCTTCGCTCTTGTTCCAGAGTCATGTCCTTAAGATAAGGACCTG ACAAACAGGAAGTTGTCATTACTGTTCTGCAAAACACAGGCTGCTGACTGAGCCATGTCC TCAAGATAAGGACCACACAACTAGAAGATCAGTTACTGTTCTGAAAAACACAGCCTTCTA ACTTTTACACAGTGCTCCCAATCAGTCTCTCTTGTGAAATCTCCCACTTCCCCAGACATG AACTTGAGACCTTAGTTTGCAACCTGGTGTCTTAGTCACTATTCTATTGCTGTGAAGAGA TACCAATACTAAGGTAACTCTTATCAACAAAACCATTTAATTAGGGGCTTTCCTACTGTT TCAGAGGTTTAGTTCATTATTGTCATGGCAGGGAGCATGTCACCATGCTGCCATACATGG CCCTGGTGAAGGAGCTGACAGCTTTGGGGTGGGGGGGAGGGATGGGTCTGGCATGGACTT TTGAAACCTCAAAGCCCACCCCCACTGACACTCTTTCTCCATCAAGTTCAAACCTCCTAA TCCTTCTAATCCTTTCAAACAGGGCCACTCCTTGGTGACTAAACATTCAAATATAGGAGC CTATAGGAGTGGGGTGGGGGTGGGGGTGGGAGGTGGATTCTTAATCAAACCACCACATTG GCCAACATAGGCTTATAGCCATATCATAATGCAAAATTTATTTAGTCCGACTTCTACTTC AAAAGTCCCCGTCAGCTTTCAGTCTTAACATGGTTTAAAAGTCCTAAGTTCAAGATCTCT TCTGAGACTCATGGCAATTTCTTAACTGTAACCTCCTACAAGATAAAATCAAAACACAGT TCACATACTTCCAGTGTACGATGACACAAAATCTATATTAGCATTCCAAAAGGGAGTAAA GGGAGCTTAGTGAGGAAGTAATGGACCAAACTGAGACTGAAAATGAGCAGGGCAAACGCC AAACTCTGCATCTCCACACCTGATGCCAAAGTGCTCCTGTGATCTCCAACTCCTTTTACC TTTGACTGCAACACATTTCTCTCTCTTGGGATGGTTCCACACCTAGTCTGCAACTCTCCT TGGCAGGTATCCTCATTTTGCACTCTCCAGTAAAATCTAAGCGTCGCCATCACAGCTTCA CTCTATGGTGGCGTTGGGCCTCCATGCAGAGACAACACTGACACATGCTTGTCCTCAAGT GGCTTCTTTGGGCCATGGAGGAAGATTTCACAGTCCCCCTTCTTGTATTCTTCCCTCTAA AACCAGAGTCATGTGGCCAGAGCTGCCAAGTTCTGCTGTTTGGTGGAGGGGGAACTTAGC CCCCTTGCTCAATTACATTTTCATGAGCTTTCTGTTGTTGTTGGTTTCCTTCACTACTTA AACTTTTCTCTAATTCCTTTTCACAGGTTGGACGCTTAGCTGGGTAGGGTCTAGCCCTGA GGTCACTACTCCTCTATTCTATTTAATATCAGGTTTTTCTTTAAACTTTTTATCTTCTTG AGCACTGGACTTGGCTCCGACACCACCTAGCCTAATACTCATTTTCTTTTCATAGTTTAC ATTTTATATTTCTTTTTGTCAAACTTACTCCTTTTCATTGTATACCTGCACAAGAGTGAC TACTAATAACCACATGACATAGCCAATACTAGGCTGTCTTGAAATCATCCATTTTAACAC CATTAATCCAAAACCCTTCAATTTAACCCCAGACAGAATTTTAGGACAAGGGCAGAAAGC AGTCACCTTCTTCACCAAATACCACATGAACAGTTTCTAGGCCACTTACTACTAATCTTC CTTTCTGAAATCTCTTGAGCCAGGCTGTCATAATCTACATTGCTTTCAGTACCTCTGTCT TCCATGCTTCTGTTAGTAAGTGTGTTAGTTCCCATTAAACCCCACTTAAAGTGTTCAACA AAACATTTTAAGAATTTAAAGTCTCCAAGTCTTCCATATTTCTTCAGCAAACAGCATGGT TAGGCCTGGTACCAACTTCTATCTTAATTACCATGAAGAGGGGAAGAGGCACCATGACCA AGGTAACTTATAAACAAAAGCATTTGATTGGGGGCTTGCTTTTGCTTACAGTTTCAGAGT TTTAGTTCATTATCATCACAGCAGGGAGCATGTCAGCTGGCGTGACTCTGGTGAAAGAGC TGAGAGCTTTACGGAGGCTGAGTGGGGGTGGGGCTAGACCTGGAATGGGCTTTTGAAACC TCAAAGTCCACCTCCAGGGACACTCTTCCTCCAACAAAACTACACCTCCTAATCCTTCTA ATCCTTTCAAATAGTATCATTGGCTTTTGTTAGTCACTCTCTGGTGACTAAGCATTCAAA TGTATGAAGCTATCGAGGCCCATTCTTATTCAAACCACTACACCAGGTGGCTAGCCTCCT CAATAGTGCAGTCTTTCTCCCTCCTCAAACTTCCTCTCCTGGGCTTAGGTTTTCCCTGGA GTCCATCTTTTAGTAATAAACCCATAGAATGCTTGTGCCCTGTTACCTTGCCCACCTTAT CTTCAGGACTGGGCAGACTGCCCTGGGGTGAAGGTAGACTGGCAGGATGGGAGGGGCAGA GGGAGAATTTTTTGGTCTTCTCTCCCAGGCTCCTCAGCTAGAGGAGCCACAGACCCAGCT GTCTGGTGTCTTAAGGAACCGTAGGGTCTTGGTGATTTATACTCAGCCTCAGACTTTCTG CAAATCTCTCCCGTTTCCTTAGCCTGTGGGAGGCAGAGACAGAGCTAGGAGGATTCTGTA ACCTTTTAGTGGGCCAGAACATGAATCTTCCAAGCAGACAGGCCAGGCCTAGCCCTGGCT CTGCTCCTGCATCTCAGTGTCTAAGTCTGTTTCTATGGATACACAGGAACACTAGTGCTT GCCTGAGGGTGGGCTGCAAAGATTAATTGGGCCAGGGCCAGAGGTTAGAATTTAGTAATA AAAGCCAATGATACCTGCCCTACAGCCTGAATCTCACCTGACCTCTGTCTGGTTTTCTGT TAAGAGAGGTCCCATTCTAATCTCCAGGATGGGGAGTTCATTGCTTCTATCTGACTCCTG CTCAGAGCAAGGAGGAAATCAGCTATGGGATCCTGATAGCTGGGAAGGTTGTGTCGAGGA GAGTGTGTGGAGACAGTTATCTGGGAGCACACAGGACTGCCCTTCAGGATTTTGTCTGCA GAGCAATGAGCTGGTTGCCAGGGAATGTCTAGAATGGATAAGATCTGTCCATGGGAGGTC TGGGTTAGAAGGTTGAGAAAATCTTGATGGGAATGTGACCCTAAGCAGACAGTGCAGAAG AAGTCAAGAGAGCAGAGAGGGTAGTGTAGTGTGTGTTTACACATACGTGTGTATGTGTAT ATAATATGTGCACATATATGTACATATATGTAGATGTATGTATGGGCATGTTAGGCAGAG AAAGGCAGGTACCGAGAGGTATGGAGTCAGTGTGACAGAGTGGCTGCTGGCAGCCACCCT TAGAAGATTGGGTTTTCAGTTATGTTAGGTCAGAAGGGGCCCTGGCATTTGCAAAGTAAA CTTTCTCGAGGTCTCAGGGCTGGGCACTTGGTGTAAAGGGAAGATATGGGAAAAAGAGGG TGGAATTTCCCAAGTGTCTTCCTTGCTTTGCTTTTTCAAATCTGTCTCTCTGTGTGCTCA AGGTTCCAGGGTTAGAAGGGACGGGGTGTCATTCCTCTTAGCTCTCAGAATCACCAACTG ATCCTGGGTAGTGGGCTGGGCTCCTGGTAGCAGACTCCTTCCTGGAGAGAGGCCCGTAGT AACCCCACTTCCCAGGACTTCATAGCATGGAACATTTGTTCTCCAGCTGTTGTGGACATT GCTTGATAAACAGTTCCTGTTCACTTCTGGGGGGGTCAAGTTTCAGCCACTCACCACCAG CTTGCAGCTACTGACTGACGAGCACAAGAGGCTGATCTCTTGTGTTAAGACTGAACCCCA CTTGAGGCCCTGATGACCCTCCCTTGTTTGTTTCTGCTGTGGAGAGGGGGTACTCACCTG GCCCCGGGAACTCTGTTGTAGGCTTCAGCTGTGCCTGACCATCCAGAGCTGCCTCAGCAC AGAGCCAGAGGTGGAAATCAGAACATCTTTATGGCTTTAGACTTTGGATTCTTTTCTTTC TGGGACCCACCCCTTGCTCACACTCCCAGCTAATCAGAGATGCATGTCTGGACTAGATCC TTCAAAACCATCTGCTTCCAAACCTGGGCAGGTGAAGATCTGAGTCTCCTTCCTTATGTC TCCCTTTAACAGCTGAGACAGTTAATGTTGCAGTGATGACATTTCAGTTCATGGAGCAGT TCATTGTCAAGTTGGTGAAGGCAGCATTTGAATGAGTTGATTATTAAAATTCTCAAATTT TTATTTGTGTGTGTGTGTGTTGATGTGGGTGGCTGATATGAGTGTGTGATTGATGTGTGT CTGTGTGTCTGTCTGTGTGTCTGTGTGAGTGTGTGTAGGTCAGAGGACTTTGTGAAATTG ATTCCTTCTTTCCACCTTTCCACAGTGCTGAGGTCTGAACGGATATTGTCAGGTTGTGCA GTAACTTTAGCTTCTGAGACACCTTTCTGGCCCCTCAAAGAATCTTTTAATTTTTTGAAA GTTAAAGTATCCACAATAGTGGTTACAATGACCCTGCCCTGGGCCTTGTGTCCCTCCTCA AACCAGCCATGGTCATCCTAAGTTCTTGCTTGACTTTGGTCTCTGGTGGTAAGCCAGACA GATGTATTGTCATCTGTGTAAGCATGGTAGTGTTTGTCTTAAAAGGTATGGTCACGTGAC CACAAGTAACAGGAAGCCCTGATTGAGAGTGAAGTCCAGCCACCACCAAGCTTGCAGCGC ATGTGACTTACAGAGAACTTATATCTAAGGCATGTTTGGATCTTGACCATGGACATGGTG AGATGAGAATGTGTAACTTCAAGCTGTCCAGTCTGTCTCATGCAGAACTAGATAACTACT GTGCTTTTTCTATCTTTTTCCTCTGGTTTTTAAAGACGGAGAATACACATTTAATTGTTA ATATTTAATATACATATTAAAGTGTATGCAGCATATGCAGTTAGGTAAATTTGTATGTAT ATATGTGTATGTTGGTTTATTTGTGTGTATTATTCTCTATCTTACTTTTCTTTCTTTTTT AAAAAACGATTTTATTATTTAATATGTATAATTGTTTTTGTTTGTATGCATGTCTGTGCA CCACATGCGTGCCTGGCACTCTCAGAGGCCAGAAGAGGGTGTCAGATCCCTTTGAGCTAG AGCTACTGACAATTGTAACTGCCATGTGGCAAGTGGGTGCTCGGGAGGAATCAAACCTTG GTCCTCTGGAAGAGCAGCCAGTACGCTTAACTACTGCTGAGCTGTCTCTCCAGTCTTCTT ACTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGACCACGTGTA CACACACAGAGGCACGTGCACACACACAGAGGCACGTGCACACACTAAAGTTAGTGTTAT TGACGATGCTCCAAAATGGAATTAACCTGGTTATCCATCAACAGGTAAATCAATTAAACT GATAGAATAAAACAAAAGGTTTATAGTATTGAAAATAATAAAATAAAAATATAAGATGTT ACAGATAAATCTCTAACATTTCATTCAGTCAAAAGAGTCAGACACAAAGATACACACATA CTATATAATTTCATTTGTGTGATGATTAAAAGCAGGCAGAGCTAGTGATGTTTAAAGAAA TAAATAAGAGTCGAGCTTTTTAAAAAGCTTCCCACCTGCTCTGAGCAGAACTGACTCATT GTGGGAATAAGGCCAAGAATTTGTTTCCTTGCCCCACCCACCTTTGATTATTAAGTATAG TCAACAACTGTGGAATGACCAAATAGGGAGCTAAGTAAGAGCCCCTGGGAGTAGTGAGAG CGCCCCCTATAGTTCTCGCACTGAAGTGCCACCCTGTTTGTCATCAGTCAGAAACTCAAC CTGATGAAAACTGAGGGGTAGGTAGCCTTGGGGTGTGATTAGGATTAGAAGGCTATGGGG ATGAGGGCATAAATGAATCCTAGTACTTTATCAGAAACAGAGAAGAATCAGATTCGCATG CATGATTTTCCTGCCTTTTGTTGAGCAATGCTTTGTGCCACCTTTAGACTCTGCCTGGAG GACAGACTCACCACTGTACGTGAACGTTTGACCTTCAATCTCCAGAACAGCGAGGTAAAT AAATCTCTCTCCTTTATTAAAGTTAGGATCCTTGGGTATTTGATAATAGATCGATGCTTC ATCCTATGTAAAAACAGAACTCTCTGAGGTTAGGCAAGCTAGGGTTCTCCAACAGAAATT ATTGAAGAAATATCTGCCATTATTTAGACTAGGTTTTCTCTCAGATTTTTTAAAAAAAGA TTTATTTATTATTATATCTAAGTACACTGTAACTGTCTTCAGATGCACCAGAAGAGGGCA TCAGATCTCATTACGGATGGTTGTGAGCCACTATGTGGTTGCTGGGATTTGAACTTCGGA CCTTCGGAAGAGCAGTCATCGGTGCTCTTAACCACTGAGATATCTCTCCAGCCCTCTTCT CTCAGATTTTTATCCAGAACCTTTGCTCATTGTCCTGAAACAGAAATGCCTGTTCCCAGA TGGTATTTTGAGATCTCTTATTCCTGTCTGTCTCAGCATAAACTTGGTTGTGGTTATTGT GGGTTCTGAGTACTCAGTCAAGATATGAACAGGTTGGAAGGGAATCATGGGAGATGACAT CAAGGAACAGTGGGAAAAGCATGAAGCTAATGATGTAATGACGATCTAGATGGTTAGAAA ACGGGCATCTGGGGGGCTGGAGAGATGGCTCAGCGGTTAAGAGCACTGACTGCTCTTCTG AAGATCCTGAGTTCAATTCCCAGCAACCACATAGTGGCTCACAACCATCCGTAACAAGAT CTGGCGCCCTCTTCTGGAGTGTCTGAAGACAGCTACAGTGTATTTACATATAATAAATAA ATCTTAAAAAAAAAAAAGAAAAGAAAAAGAAAAAAGAAAGGGGCATCCGAACCAGACTGA GGTGGGAGGCTGGGCAAATCTGGTAAGACTTTGACGTGCGTACAGTCAGCACATCTTGAA TTCATTAGTATTTGTTAAAGCCTACTCGTGATTAATGTCAGCACTCGGCAAGCATGTATG TAAGTTCCGTGTATTGTGGAATCTCATTAGCGTTCTCCTCCGTCCACACGCCGAGTTCAG GCCTCTGAAGGCTTCCTTTGTTCTCTTACTTGCCCATCCTAACTTTCAACCCAAGGTCTC TCATGGAACCTGGGACTCACTGATTCAGATAGATTTGTTGGCCATGCAGGCCCATGGGTT CCTCCACTCTGTGCCTCTCCAGTGCTGGGACTACAGACCCGTGTCACTGTGCCCAGCTTC TCACTTGCATGCTGAGCACAGAGACTCAGGTTCCTAACCACGGAGTCATCTCCCCTGTCT CCACACAAGTTGATTTTCACATATGCAATTACCCATGTGATCATCATCGAATTCAAGGCA TGGAGATGTCCCTAACTGTAAGAAGTTACCATATCCTGCCTGCTCTTAATGGGGGTACTT GCCTGAATCTCCGATTAACCATGATTAAGCCCTCAGAAGATCCCAAACTTAAAAAGCAAA TGCCACCACATTGAGACCAACTTAAAATCTAAGCCACGCTGTTTATTTTTCTCCAAAGTA TAGATGATACAAGCCATATGTCAGGGCCTGTGAACACTGGGCTGAAGTGGTGACTCTCAG GGGCACTCCTGCTTTTCAGGCAGGGTTGGGGGAGTATGGAGTGGTTCAGTCTCCTCTGCA GCCTCCTGTCCTAGTAGGTGGGCAGAGCCAGAGTCAATGCCAATCTTCTGTTACAAATAA GGAGAAGGAGGTTCCGGGGTGGAGAAGAGAAATGCAGGGCTTAGCCAAGAGGTGCTTTTT TTTGGTTTTCGAGACAGGGTTTCTCTGTGTAGCCCTGACTGTCCTGTCCTGGAACTCACT CTGTAGACCAGGCTGGCCTCAATCTCCCAAATGCTGGGATTAAAGGCGTGCGCCATCACG CCTTAGTCTTATGTGGTGTAGTTTAACACTCTAGTTTCCGGGTGGGAAAATGAAATCCCA AAGATGTAACAGCAGATGACAAAGGACAGAGCTGATCTTCGGAGCTAGGAGCCTGGAGGT CAAGCCTTGCTCTGAGCCTCTGAAATGCCAGTCTATTCTGGAACATTCTGAGTTCTCCGT GCTTAATGATCTTGAAGACAAACCTCCGAAACCTCTGCGAAGCCAAGATTTCCCACGATG AGCAGAGGACTGAGGAGGAGTGTACGGGACGTCTATGTCAGGTGACAGGGCTGAGAATGG GCACACCCTGGACACCAGCTTTATGCCTTTTTTGGAAAGACAGTATTGGAGGAACTAGGA AATGGATGGAACATGTCACTCAGTGACACAGTGCACATGGCTTGGAGAGTCTCGCTGGGA AACCGCTGCCTTAGAACGGACAAAGTGAGGGTGGAGAGGCTCTGGGTAAAGTGGGAAGCC TGGACTTCAACCTGCAGAACTTGTAATCTATTCTGATGACTCCTTGGGCATATATGCCAC GTTGTCATAGGCAGGAGGTGGAGAGACTGCTGGGCTGGGGATGTTGAAATCCGTGCCAAA GGCATTGGGTAGGAAAATCACAGACTGCAAAGAAAAAAAAAAAAAAAAATCCCAAATTTT GGGTGGCTCTGCGGTCTTCGGGGAGCGTTGCAATAGTGCCACCCCGTGGGTATTCAGAGA ACAGCAGCTCTCTCACACAAAAGCATCGTGTAACTGACATGTTAGCAAACATTTTCTAGG GTCAGTTATGAGCTAGGACTTGGACACACTGAAGCTAGCAAAGTAGACAAAACCTCATTT CCCCTAGGGGCTAGTGAGCTGATATTTCCTCTCTGGATAGTCTCTGCTGAACCCGGGGCT TCTATAGTTCTTGCCTGAACATGCTGCTCTCACAGTAGTAGTCACTCACTGGGCTCCTTT AATCTAGTTCATCCTCCTGCTCCAACTTTAAATGGCACCTGCCATCCTCTACATTCTCCT TCCAGGCAAGCCTCTGCGCTATCAGAACCCCCTCTTCCCACTCTCTTCCACCCGCCTCCT ATTTTCCCCTGGAAAAATGAGCTTCCACTGAGACATGCTGTCTTTTCTGATGTGTCCATC TGTAGGCAGTCTGTGGGCTCCTCTGTGCAAGGTGCACGCCTCGCCCTCCCCAACCCTGTC CTCTGATTCCAGAAGAATTTCAGTTCTGCCTATAGTGTTGGCGCCCCCAGTGGCCACGGG TGAATAGTCCCATTTCAAAACTTGAGGTTCTCATCACAGCTCAGCCACAAAGGGGAAGTG GGAGGGGCTGCAGGAGTAACCTCTTCCTGGACAACAGGCAACCTCAGGGGCTCTGGACGT GGTGTGAGAATACTTACTGCGTTAGTTTGAGCACGGGTGGCTTGGCACCCAAAGTGGGTG GCAATGACAGCGATGAAGAACTCCAGGATGGTGAAGATGGTCAACACGGCAAGGTAGCCC CTGCCCACATCCTGAGAACCCAAACCCACAGTCAAGGCAAACAGAGCGTTTAAAAGTAAA GAGACCCCCTCCCCCCCCGGACCAAGAATAACTTTCCCAGGCAAGAGGCAGATGTGTGTA CCTGGCTCCAGCCTTCCTGACTCCAGCCTTGGGCCTCACTCCTTCCATTCTACGGGGTCT CATCTCCCTTCCCCTGCCTTCCCCATCCGACGTGGGGTAGGGTCAAGGTGTCAGTACACT CATGAGGTCTACTGGAGCATCAGGCTCTGCAACTAGCCCAGGACTGCAGACTCTTGGGTC TTCCCTAGTCCTGGCTATAACCCTCATCTCTCTGGGTTTATCACCCCTTGGGACATCTGC CAACACACCCAGTTAGTGACACCAAAGTCCATGAGAAGAATGGCTGTCCCCGCGAAGGCT GCCATGGCACTGAGGATGTTGGTTCCCAGACTGCTCTTCAACTGTGGGAGGAAGAGGAGC AACAAGAAGAGGCAAAGAGGAGAAAGGACACTCACTGTGCCCAGTCTCCTGCACCCTCCT TCCCGGCCTAGGGGCTTGGGGCCATTAGCATTGGAGGAGGCTGGGTTTTCCTTTCCCCAT TCTTTCTCTTCTCTTTCCCTGAGACCCCAAGAAAAGGCCCTGATGCCTCTCTCTGCTTCT TCCATCCTCTTGGGAGCTTCTGGGAAGGAGGCCTAACCCTCTTAGTGGCTTTCCTGGGAC ATGTTTGCAGCATGCATCTGCCACCTCCCTCCCAACCCCCAACTTGTCTTCCCTCAGGCC CAGGCCCATCTACCTTAACAACTTGGTGGCTATTCTCTTGGGGACCCTTCCTGCGACTGC CTCCTCTGAAAGTCTGTGAAGACTTTATCACTAGACTCTTACCATCTACCTTGGGTGGCA TTTTGCAAGTGTCTCGTCTCCTCCTTCTGTATGTGGATGTTTAAATTCCTTCTGTGGACA CTTAGAAAATCTCCAAGGAGTGCTTGTTGAATGGGCCAAATGAGTGAGCAGATGGGAGCG GGGTCCCGAGTGGCACCCAGGTAGGTGGGCACCATCCCTATCCCTGGCTCTCTGTGTCCA TTCAGACTTACCAGGCAACTGGTGTGGTTCCTCTCAGCTGCTACGGAGAGGGACCCAGAG ATGATAAACTGTGTGGGGAAGAGAGAGCCCAATGGGGTTTTGGCTGAGACACGTGCAGGG AGCATCATACCTAGGTCCCATCAAGAAGGTAACAGATAGAGGGGCATCAACTTCCTTGTC TGCATCTTGGCCAGGCATCTTGGATATAGTCCTAATCTTAGTGGTTCTGTAAGAGGCCCC TGTCCTTGGGCATGGTGGCACACGCCTTTAATCCCAGCACTTGGGAGGCAGAGGCAAGTG ACTCTGTGAGTTCAAGGCCTGTCTGCTCTATGTAGTGAGTTCTAGGACAGCTAGGGCAAC AAATAGAGACCCTGTCTCAACAAACAAACAAATAAACAACAACAACAAAAACAAACACAA AGAGGCCTCTCTCTGTCTTGAGACCTCAAGCCATGGTTTACTAGGTATGCATTTTCGTTG ACGGTATATTACTGAAGTGTCATAGTACACTCACCTTTCCTTCTAATATTCACTTAACAA GTAGCAGTTGGGTGTCAAGAACATAAAATGAAGAGCTACTTCTCTCATATACACATGAGG GCATGTGCATGCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTATGTAT GTGTGTATGCTTGTGCATGCATGCCTCTGTGTGTGTGTACTTGTGCATGCGTGCCTCTGT GCTAAGGTCAACCTTGAGTGTCATTCCTCCATAGGAACTGCCCACTTCGGTTTTGAGATA CGACTTCTTATGTGGACTTGGGCTCACTGATTATGCCAGGTGGTTGACCAGTGAGTTGTG AGAAGGGCTGTCAGTCTCTTTTTCACCAGCCCAGGTGGGCTTTTGACAAGGGTGGTGGAG GTAAGGACTCAAGCCCTCACTCTTGCCGTGTAAGTTCATTACACACTGAACTCTCTCCCT GGCCCTGTGAAGTTTTAAGATAAAAGCTACATATGCCCCGCCTAGGCCGCAGGACCCTGT TGTCTCTCGAGAGACTGACAAACAGGCGTTTATTACCCCTCCTACCATGGGAATGGCACA CATTTGTGACAGATTTTGAAGCAGGAGGGATTTTAAAGAACAGTGCTACCTTTGTTTCTT CCCAAGGCAGTGCCCACTTTAGACTCCTGCTGGCCAACATGTCCCTCCCTCTTGGGTCCA CTATGGACCACTAGAAGCAGGGCTTAGAGCTTGTTCCCAGCCATTTAGCTGTAGCTGTGA AGTTTCAGCAATGTTGGTCTCTGACCTCCACTTTTAGGGGCTTCTGAGCTCTTGCTGAGA CTGTCTGGGATATGCAGAGGGGACTCTACCGTCATGCACAGCAGAGCCTCAATGAAGACC CCGTTAAGCTCATCAGAAAGCCGGTGCTTCCTGGAGGTAGCTGGAGGCTCCCCATTCCCA GAGGCACTGGCCCCTTTGTAAGGCACAGACAGCAGGGCTATCTTGCAAACTCCCTCTCTT TGGGACCTCAGAGCAGACAAGGTAGCCCTGATTTGGTTTTCCAGTGATGTATGACCAGAA GAATGGACATTGGATAGGGAGACTCCCTACGGACCAGCTCAGGCAGGGCTGGAACCCACA GAGAGAAGCAGGGGTGGGGTGGGGGCTGGGTATGGTTGTGGGGTTAGGACTCAGGTAGCC CAGGTGTGATTAGGACACTGGCCTGCTTGCTCCTCACCCGTAGTTTCTGGTAGAATAGTG ATGATAGCTATTACTCCCATATTAGTCTTGTGAGGGGTGAGTAAAACTCTGACATACGAT AGGCTATGGATAGGAAAATGTCGGAAGTGGGACAGGGCGAGGTGACTTGGGCAAAGCCAC TCCTTAGCCGAGGATGGCTACCCGCACTCACACAAGCTCCTCCCCAGAAGGGGACGCCAC CTTCGATGAAGAGCATCCCCAGGTGGCCTCGCCGAACCATAAGCAGGACGCTGCCGAAGC CAAGGTGGATGAGACCGATCAGGATCTGCACCGTCTGTGGGAAGCAGAAAAGGCTCACGC CACTGACCTGGGACCACGAGCTCCACACCGCCCTCTGCTGTCCTGCAGACCTGGCTCTCC ACAGCTCCTGGGGAATGAGCAGGAGGCTGAGGCCAGCCTTAAGGTAGAACCAGCTCTCCT CAGACTAGGAGGAGCTCCAGGCCACGGCTTTGTGACTGGTTGTCAAGGACAGCTCTGATT TGCTTTTCTGATTTTCTTAGTCTTGGTTCCTTGACTCTCAGCACGTTGGTACCAAATGCC TAGTTTGCCTTCTTCCTGTTATCTTTCCGTAGCCCATCCTGGAGGTTGGGGGCTACACTG CTTGACTGAACTTTCCACTTGGGTTTCTTTCCATCTCTCTTCCTCCTGGCCCCCTCTTAT CTTTACCTCCTCCTCTTTCTTCTATTTACCAGTGCCCCATGGAAGCGGGATGGTTTTCCT AAGGGTGGGGACTCTCTGGGAAGTGTGGCCTTGTGATAAGTTCTGCTGCATTGCCTTTCA AACGTTTTTGTTTGTTTGTTTTTACCAATTCACATGCCTATTTATCCATCACCTATTTTT AAAAACCTCAAAATTTATCATCTATCTTATCCATCAGTCACCACCTATTATATATTATAT ATTCTATCGTCTACTTGTCTTACCTACATATTTATCCTGTCTTACTTATCCATCCTATCT GACATTTATCAATCATATTTATTAATCATCATCTACCTCTTATCCTCTTAATCAATTTTA TTCATCTACCATCTATCTGTTTTTCATCTATCTATTTCATCTATCTAATCTATATTTTAT CCTTCTTAGAGACCACTATCTAGGCCGTTTGAGATGGGAGAAGGGCTTGGAAGCCACACT TGGTGGATTCTCAGCTCTACAGGAGTTGGCTCTCACCTATCATTTCATTTTCATCCCTTG TCAGCCTTTCTTTTATTCATTACATTACAAGCACGACAGTATTCTGTATCTTTCGTTGAC AAGCCACACCCATTCCCACCTCAGGGCCTTTGCATTTGCTGGTCTTCATGATAGTTAATC CTACCCCTCACCCATCCTTCTGCCCATCCGCTCTTGCTGGGCTGGCTTTAACTTGTAAGA TCTAGCCTCAGTGTCGGCTCCCCAGAGAGATATTTCCGTCTTTGCTAGCGTTGCCGTCCC CCATCCATCATTCTTAATCCTCTTTGGAGTTCTGGTCATTTATTTTCTCATTTATTGGGT GAGGTCAAAGGGGGAAGGGAATTCTTGTCTGTGTAGTGCATGAATGAATTCTCACATCTA TCCCCTGCCTCCACCTCTCCCTGTTGAGCGTGAGGCACTCTGCCTGCCCAGCAAGTTTGT CTCAAGTCACATGACAAGCTGCCCTTACCCCTAAAGCTTTGGGTTCTCCGGTCAAGAACG TCTCCATTGGTCTAAGATCAGGTGGTTGAGTAGCTCTGGGCGCCTGCGCCCCCAGCTGTG ACTCTTCGAACTGCATGATCCCTGGAGGCTGGCACATGGAGGTGGGCAGAATGGCTGGAG GTGGGCGGAGGCCGCTGGCGTTGCTGGGCGGGATGACAACGAACACACCATTGCTGGCAG GAGGTGCAGACATCGTGTTCAGAGAGCCTGGGGGACGAAGGCTCAGGAGATAACAAGGCA GTAGTGGTGGTCACACATATGTTTAAGGCTGTCGACTAAATGGTGTATCTCCCAGCTTTT GCTTACTGAGGTCACAGTAGAACCCAAATTCTCAGCTACAGCTGGGGTTAGAGAAGAGAC TACAGAAACGAAGTGGGTTCTTAGACTTTTTGGACTCTTGACTCTGATCTTGATTTCTCC TACATTGCATGGAAGGACTTTTATTTCAATGCTGGGCGTGGAACCCAGCCTGCACCTGAG GCAAGCCCATCACCATTGCTGAGCCACATCCCCAGCCCAAGTGGAACCTTGGAAAAAAGC TTCTATTTGAACATCCTTCTTTCCCTAGAGAGGGTGAATGATGGTTCAAGAACACACAGC TCGGGAAGGTGGAGCTTAGCTGAAGTACCATTTTATCAAGGAAAGAGAAGGACCAGGCAA GACGTACCTCTTCCCTCCCTCCTCTAGGCCTACATCTGTTAACTGTGGATACCTAACTAC CCTGGGGCAACATCCTGCTCTCTTTGACTACCCAAGGAATAACCACTATTGTAGCCAAGA TAAATAAGGATTATGAAAATCTTAGGTGTGGCTGGTCTGGGAAACTCTCTAGGGAACATT GACCAGTTAGCTAGATGTCAGGTGGTAGCTTCCCAGGGTGCTGCAGTCACTAATCTAGTG GATTATATGACATTAAACAGCCATCTGCCTTGCTGGTTTTCACATGTGGTGAAGAACCCA GCAGTCCAAGTCACAGCTCCATGACAGAAGCCAGGATTTGAACCCTGGCCCATGTAGTCA CTGTGAGACAAGGGGCTAGATGGTAACCTCTTCCTGCTTTACTTTTTGGACAAAAATGTA GGGGGAAGGCCACAGAACCGATCACATTATAGGCCTGGTAAAGGCCACAGTTTACACAGT AAACTGTTGTAGCATCTTCATCTGAAGTATTTTTTTTAAAACACATCATCTATCCAGCAC ACAAACATGTATTTACTCATGGCTTGTAGGACTGTGGTTTGTGTTCATGAGTCATTACAG CTGCAAGGTCACACAGCCTGTGAGAACCAAGCTCTGCTGTGCTCCAAGTTACTCCATATT GTGTTAAAGAGTGGCTTTGGGCTGTGCCTTGCCCTGGGCGACTGCCTTTGAGAGGCAGCA TTTGGCCCTCCTGTGAGTTCCAACAGTGAGTCATGATGACTCTGTCTCACTGTGTGCACA AGAACCACCACCTGCCCAGCACCACCCACAGGGCACAGACAATTTACTCCTAAGGATGAA AAGTACCACTTGGACCTATGAAGGAGACGCCTGGCACCGCAGTCGGGATGGCCCCATTGA CCTGGCATCTGATCATCCAATGTGTGTGTCATGGGACCAACAGGCGGACTGTCCGGCTCC AGCTCAGCTTGGTTTCCACCGACTGGTGGAAAACCAGTCTGTGTCTTTGTCTGAACCAGC CCTGCACTTCTCTATGGTCCTGCATTTCCGTAGCACCCCTCAGCTCTGCAATCCTGTGCC TTCAGCTCTCCAACTGGGGTCCTTAATATCTTATCTAACCAATGAAGTGATGCAGTGCCC ATTTGTGTCTCTAGTAGCTCTCTGCCTCTGGTAAGGTCTCTTTAAACTGTGCTGTGATCT CTGTACTTTTGAGGTTATTCTTTAATACACACACACACACACACACACACACACACACAC ACACACTGAGGTGTATAAGGTGTGATCTGAGAGTTAACACTAATACTTAAGATCAGAATA AAAACACACATGTTAGTCAGCAGTCAGCTATTAAGGGGAAATTGGAAGTATTTGGCTTGA AAATTTATTGTTAGTCAATAAATTCTGGCACTGTGGACAACACAAATATACCCATCTTTG TTTCTGGAATAGCAGGCTCTTGACATAGTCCATTTCCTGTGTTCAGTAGATGAACATCTT TATGCTAGATATTTGCTCTGTGATGAGCCTGATTCGTCTTGGTGAGTGTAAAACACAAGG GTCCGGTTGGACCTGCCCTTGAGATGCATAGTGAGTCTCCACAAAGGATGAAGTAGGGTT CCAGTGGTTGGAGTACCTCCAAGGGAATGGCAGTGGAGGCATGGGGTGAAATTGGCTGTC ATGAGCATTTTCTGTCCACTGTAGGTGATTAATAAATGTTTCATAAGTTGGGGAGACAGT TTAGCAGGTAAAGTGCTTGCTGTATAGGCATGAGGACTGACCTGAGTTGGAGTCCCAGAA ACCCATGTAAAAAGTTGGGTGTGGGCTCGAACTTGTAAGCCTAGTGCCGGGGAATCCTTG GGGCTCTCTGGCCTGCCAGCCCAGCCTACTTGGTGAGCTCCAGACCAATGAGTTCCAGAT TCTCTCTCAAAGAAACAAAGTAGTTGTCCCCTGAAGAGTGACATGCAGAGTGGACCTCTG ACCTCCACACACATGCACATGCCTGGGTACCCCCAGCAGAGAGGCAGGACTCTGCACGAC ACATGCACACAATTGCACATATATGAACATGCACATACATGTACACACACACCCATGCAT GCACATACATGCAAAAGAAGAGCATGTTTCAGGTAAATAGTGTTATTGAACGACAATCCC ATGCAGAGGGTGGCAGAAGTTGTTTGATATCTTTAAGGACTTTCTAATGTTTCTTCCAGC CAAAGGTGTGATATCAAGAGCATCTAAAAATGGTGTTCTTACTTCCCACAAGGTGGAGCT CAGTTGGGGCTCTGGTTTCCAGGCCCTCACACTGAAATGATTCTTAGCAGACATGAGTAC TGCTTAAGTCAGCACTGGCAAACCTTCCCTGCAGAGACTCAGCTAGCAAAGGTTTTGGGT GTTGATCAAGTAGTTCCTGTTTTAAGTAGGAGATGCCCCTTGTAGTGTGAACTAGACATG GGCAATGAATGCATACATAAAAGGTGGGACTGTGTTTCAGTAAAGCTTTATTGACATGGA CAGATGGCTTGGATCCAGTTGGTGAGCTGGAGTTTTCCAAGTTCAACCTCAGAACACTGC CTGGACCATAATACATGTTGATTAGAATTTCCTTGTTGCTTTAGATGTCAATTACACTAA TTGCTATGATTTGGAGTAAGAAGGAAAATAAAATAAGCTTCCAGATATTTCTATACAATG AAGGTAAATGTGGCTATGATGGCTTTGGCTAGAGTTTGGGTCTTGAATGTCTTTCAAAGG CCCACATGTTAGTTAGACAAAGGCTTGATAGACTCAGGATGCTATGACTGACAGGTGACA GAACCTTGTATTACTTTTCTTATTCCTGTGACCAAATACCCTAAATATGCATGTGAAAGC AAGTTGGGTTTATTTTGACTTAGCACTCAAGGGAACACTGTCCATCCATCACGTCAGGGA CTGAATAAGTCCATACTGTCAGGCAGGAGTGAGGCGGCAGGTTGCACTACATCTGTATCT AGGAAGCATCCAGAGTGGGAGGAAGTAGGGCTAGCTATGAAACCTCAAGCCCTGGCTCCA GTGAGCCACTTTCTCCAGAGAGGCTCCGCCTCCTAAAGCTTCCACACCTTTCCCAAACAG TGTCATCGGCCTGAGACCAAGACTTCAGGCCATAATGTCCTACCGCAGTCTCACATAGGC AACCAAACCTGGACTGGGCCAGAAGCAAACCTGCTCTCTCTCTACATAGATCATCTCAGG CATTTGCTGTAGCTAACATAGCTGCCCCTCTCATCTCAGAGGCTGGCAGTGAGGATCAGA AGTCAAAATGGACCAGGCTGTTCTTAGAAACTGGCAAAGGGACTGTGGTATGCTTGTTTC AAAGCAGTGTGGTTAGCAGTCCTAGGTCATCACTGACCTTTGAAACTTGCTGAACTATTC ACAGGGCACAGCTCCACCCTGCCCCAGGTTATGGGATTAGCAGCATTTTCTGACCTTATT CTGAGGATAGGACACTTCTGACACATTGCCTCTCACCTTCCCGGTGACCTGATAATTTTC ACCATTTATCATCTAGGTGTGCTTGCAGCAGAAAGGGGACATGCTTAAGGCAACTCAGCT TGTAAACTTGAGGGGAAAGACTCAAGTCTAAGTCTGTCTGTGTCCCAGCCTGCACCTGAC TGTCACTGCTGCCTCCAGGGACAGTCTTTGTCATTTGACCATTTGTTCTGGCTATTGTAT TCTGGGTGCCTGGCATTTGGTGTGGTTCTGTGATTTGTTTTGGTTAAAATCTCTTGAGTG GCAGTAAACTCACAACTTCTGAGCTAGTTGTTCAGTGACCAGTCTGGGGCATGATGGATA GACTTTCCCCTTTGTCACAGTACCTAGCCATCTTCCAGATAGAGGCCATTCTATGTGCTT CAGTTCCCAAGTGAGGGAAGTCTTCAGGGCTGTGAAGCAGCAGGAGGAGACCATCCCCTG CGTCTATGGCACTAAGATGGCAACGGGACATAGCTGAGTTGGTAAAGTGTTTGCAATCCA CGAGAACCCAAGTTCAATGCCCAGATCCCACATAAAAATGCTGGGCATGGTGGAGTTCTT TGAATCCCAGTGCTGAGGAGACAGATCGAGGCAGATCCCTAGGGCCTGATGGCCAGCCAG TCTGGCCAAACTGGCTAGATGCAGGCTAGTGAGAGACAGTGACAAAACAAGGTGGGTGGT GCCTGAGGAATGACACCTGAGGTTGTCCTCTGGCCTCTATATGTATGTGTGCACACCTGT ACATGTATACACACACATGCACATTGCATATATACATACATATGCACACATACATGGACA CTAAGCTATGTGTTTCTGAAGCACACTCTAGCTTCTCCTGACCATTACATCCTTCTGAAA TGGAGAAATATATGTAAGACACTAAGAAGAATCTATGTACTCCAGTAGTCAAGAGTATAG GAAAGAGCAGGAATGATATACAATTCAGGCTAACAAAGCAGAGAGGGCGAATGCCTCCCT TGAAGTCACATAGCACCTCAGTGGATTAATCTGTGATAGATCCCAGAATTTCCACTTCCC AGTAGGGACCATACTGACTTTAGAGAATTCACCCACTCCTGGGCCTGAATCCTTGTTTTG TCAGAGTGAGGGAGGCCCATTGCTGTACGTTCTTCCTTGGAACAATAGTTCAGATAGGCT TGGCATTCCCAGGTAATCACATTAAGAACCAAAGGGGGCTGAACTAGCCTGGCACAACAG TGCTTCCCCAAGTAAGGCGGTTTAAAAAACTACTAAGGATAGTTTAACCCCCTGGAGTCA GAAAAGGTGGAACTTTAGGCTAAAAGGACACACTTGCTTTCATAGTTGCCATTTCACCAC GAACAGGTGAAGATCATGTCTGAGGACTATGATGGATCATATGGGTACTAGGGATATTTT CTGAGGTCAGAAGGGCTCTCTCTGGGCTCCCACTGGGCTCAAGGCACCCAGCAGGGAACA CTTGCATCATTAACAGCATCTCTCCCAGGCGGGTGGTGAGAAACATGGTCACACACAGAC CCCGTGATCCTCAGGAGAAGAGAAACACCTACAGAAATAGGCTTTGCACTCTCGGTGGGG TAAGTGGCAAACCCAAGCAGGAATACATCCTGAGATTCACACTCTCCTGTGCCCTCAGCT CCACCGAAAGCCAGTGACTAACGAATCTGTGGTATTCCAGGTGACTCCATCTCTGTGCTT CCATCTTCCTTAAGAACAATCAGCCAGGGTATCCCTACCACTCATGCATGCATAGGAGAA GAAGGAAGGAAGTCATTGCACCCTGCCGTAAGGGAACAGCTGCCTGGACACTCAGGGCAT CTAGGGCAGCTGTGTTGATTATCAACTGCTGAATGAGCCGTGGGTAATAACAGCCCTTCA TGGAAAAGCCCTTTACAGTTTATAAAGAGCTCTCCTACAGACTCTAGAGCAGCCCTGGGA AGGAGGTGCAATGGAGGTCACTTTGTGGAGTGGGTGGGGGGAGTGGGGCAGGTCATGGGC CTGGAAGGCTGATGTGTCGGTCAGAGGTGTTAAGGCTGAACTGTCAGCTGAGACCAGACT CTGAAGTGAGTGATGTCACCAAGGGTGTCAGGGGACTTGCAAAAGGCAGGTGGCTAAGAA GCTGTAGGGTGTTTTTTATACCTTCCCTCTCACAGTTGCAAGTAAGGTTAAAAGTAGGCT TGACACTGTGCAGGGAGGAGGGGAATATATCTCTGGTTATCTTTTGCCATGGCAGAGAGG CTGGCTCTGAGCAGCTTGTCCTATGAGAAAGTCACATGTGGATCTTTTCATTGGGTCTGC AGATTCCCAGCTTAGGGGAGAGTTCTTTTATAGAGAGGGACACAGGAGAGAGAGAGAGCC CAGCAATGAGATGTGTTTCTGTAGAGACACCCCTTTAGAGAAGTGGCTACCAACTCACAA AGCACCCAGCAGGTACATGGCCCCTATCCTCTTTTTCCTCCTTGTCCACTGCTCAGCCTT GGGGATGCCACTCTGGCCAGCCACTGTGCGTGTGCAGGGGGGAGAGCAAGAAACAGCGTG GAAAAAGATTAAAGGCAGCAAACACCCTTTGTATTTGCTGAACCCAAGCTGAGGAGCAGC CCCAGGTCTAAGCAGGCTAGTTGCTAGTTACTAAATTGCTGCTGTTTGGCCTGAGGGTGA CTGGAAAAGCCACAGACTGCTTAAGTGTCACCTTGCTATAATCGCTGTGAATTTTTACAA ATTAATGTAAACAGTTATACTTAGGAATAGCTATTTGCATCATAGAATATAAAATTTGAT TTATACCCTATAAAAAAGAACCAACATTCAAATAGAAAAGAACTTTACAGATCCACCTTA GACTTGATTAAAATCACACACACACACACACACACACACACACACAGAGCAAAGCCCCTA AAACTCCAGAAAGAGAATAGTGCTCAGCTACCAACATCTGGCCCCATGCTTGGTGCAGAG GAAGCCTTCAGTTCTTCTGGGCTTCAGCTGTTAACAGCCTCAGTGGCATGAGTATCTACA GTGATGGGCTGCCCCAGTATGTTAGCTGGAGCACCCTTGGGCAGCTAGCACATGTCTTGG AGCATCTCCAGAGAGCCTCCTCTTCCACCCAGGTCCCAAAGCAGCTTTGCTTATTTTCCC CACTAGAGTTTCTTTTTTTGGGGGAGGTGCTGGCAGCTGGAAGGGACTGACTCTAAGGGG TGGGGATTCTGGGATGAAATATATGGCAACACATCTGGGACTTGGCAGCTTGGCTTGTAG TTGAGTCACAGACCCTGCATTCAGGCTAGTAAGAATCCACATTACTATCTGGTGAGATGA AGTAGCTGAGTGTTTGTGGGCAAAATGCCTAATCTCTCTGGGCCTCAGTTTCTCCAAATA TCATAAAGTGGCTGTGTAGTAGTGGTAGGGTGAGGTGTTTTAGGCTTCTAAGGGTTTCCT ATACATACATCCTGGGTCTGCAGCCATTTCTCAAACTAGGCAAGAACTTGCATCTATTTA AGTCTTGTCTGTGGCACCAGGCATCTTGTCTCCAGTCTCAGCGTTTCCAGGACAGCCCAG ACCCACCCCACTGTCCCAGAAGTGATGTAAATTGTCCCACCAGATGTAAACACTGTGGGG AGGCAGATCTCACAGTCCTTTTCTCCTACCCTCAGGTTGGACCTCACATAACCCATGGCC TTCTACCAACCCCCTCACCTCCCTGCCCCCCTGAAGCTGAACAGCAGGGACAGCCAATTC CTTTCCTCGACTAATACTTCCCTTCTGCAAATGACACAGTATTTGGTGGGAAGACTTTTC TGGCAGTGACCCTGGTCATATTCTTCTCCTCTCATTAGAGAGGGGACAGGCAGAACACCT GTGCATGGGTGGAATCACCTGACTAGGTTGGACATCTAACTTGAGCTGGCTTCTGGAGGA AGGGACTCTCTACTTCTTGGGAGGGTGATTGTCTCCCTGGGGTCCCTGGGGTCCCTGGCA GGTACCCGAGTGATCTCTGGTCTTAGCTTTGAGGAGAGAGGACAGACAGCCTTCTTTTGT CCCCCTTCACTATGCAGTGGGTCTCTTGTTGCCCTGAGCGGGAGTGGGCAGCCCTAGGAT CCCACTTCCCAATCTTATACCAGGTGGGTTCCCTTCAGTGACTCCTTCTCTCGCCCTGGG GGCCTCCACAAACCCCTGCCTCTTCGCTGGTTATATTCCCTGGCTGGCCTTTCTGGAAGG ACAATGGGGGTACTCACCGGCTTGCCACGGCTGCTGTACCGGCTGCTGACTCCCCTCTGC CTCTGCGCTCCCACATTCACACATCATCCTGTGAAAACCTTGCTATTTGTGTGGGGCTTG GAAATCACTGCTTAGGAGCTGCGCCTCTG bcftools-1.21/test/csq/ENSMUST00000133836/ENSMUST00000133836.fa.fai000066400000000000000000000000221467060157400225030ustar00rootroot0000000000000019 51869 25 60 61 bcftools-1.21/test/csq/ENSMUST00000133836/ENSMUST00000133836.gff000066400000000000000000000551411467060157400221350ustar00rootroot0000000000000019 ensembl_havana gene 100 7885 . - . ID=gene:ENSMUSG00000024732;Name=Ccdc86;biotype=protein_coding;description=coiled-coil domain containing 86 [Source:MGI Symbol%3BAcc:MGI:1277220];gene_id=ENSMUSG00000024732;havana_gene=OTTMUSG00000033058;havana_version=2;logic_name=ensembl_havana_gene;version=7 19 ensembl_havana processed_transcript 100 5951 . - . ID=transcript:ENSMUST00000133836;Parent=gene:ENSMUSG00000024732;Name=Ccdc86-002;biotype=processed_transcript;havana_transcript=OTTMUST00000082545;havana_version=1;transcript_id=ENSMUST00000133836;transcript_support_level=1;version=1 19 havana exon 100 1908 . - . Parent=transcript:ENSMUST00000133836;Name=ENSMUSE00001268792;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001268792;rank=4;version=1 19 havana exon 2097 2171 . - . Parent=transcript:ENSMUST00000133836;Name=ENSMUSE00001272435;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001272435;rank=3;version=1 19 havana exon 3902 4031 . - . Parent=transcript:ENSMUST00000133836;Name=ENSMUSE00001210915;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001210915;rank=2;version=1 19 havana exon 5588 5951 . - . Parent=transcript:ENSMUST00000133836;Name=ENSMUSE00000787430;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000787430;rank=1;version=1 19 ensembl_havana transcript 100 7885 . - . ID=transcript:ENSMUST00000025639;Parent=gene:ENSMUSG00000024732;Name=Ccdc86-001;biotype=protein_coding;ccdsid=CCDS29593.1;havana_transcript=OTTMUST00000082544;havana_version=1;tag=basic;transcript_id=ENSMUST00000025639;transcript_support_level=1;version=6 19 ensembl_havana three_prime_UTR 100 1788 . - . Parent=transcript:ENSMUST00000025639 19 ensembl_havana exon 100 1908 . - . Parent=transcript:ENSMUST00000025639;Name=ENSMUSE00001210169;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSMUSE00001210169;rank=4;version=1 19 ensembl_havana CDS 1789 1908 . - 0 ID=CDS:ENSMUSP00000025639;Parent=transcript:ENSMUST00000025639;protein_id=ENSMUSP00000025639 19 ensembl_havana exon 2097 2171 . - . Parent=transcript:ENSMUST00000025639;Name=ENSMUSE00001254304;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00001254304;rank=3;version=1 19 ensembl_havana CDS 2097 2171 . - 0 ID=CDS:ENSMUSP00000025639;Parent=transcript:ENSMUST00000025639;protein_id=ENSMUSP00000025639 19 ensembl_havana exon 3902 4031 . - . Parent=transcript:ENSMUST00000025639;Name=ENSMUSE00001226335;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00001226335;rank=2;version=1 19 ensembl_havana CDS 3902 4031 . - 1 ID=CDS:ENSMUSP00000025639;Parent=transcript:ENSMUST00000025639;protein_id=ENSMUSP00000025639 19 ensembl_havana CDS 6897 7852 . - 0 ID=CDS:ENSMUSP00000025639;Parent=transcript:ENSMUST00000025639;protein_id=ENSMUSP00000025639 19 ensembl_havana exon 6897 7885 . - . Parent=transcript:ENSMUST00000025639;Name=ENSMUSE00000361340;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSMUSE00000361340;rank=1;version=6 19 ensembl_havana five_prime_UTR 7853 7885 . - . Parent=transcript:ENSMUST00000025639 19 ensembl_havana aberrant_processed_transcript 4126 7870 . - . ID=transcript:ENSMUST00000189018;Parent=gene:ENSMUSG00000024732;Name=Ccdc86-003;biotype=retained_intron;havana_transcript=OTTMUST00000121551;havana_version=1;transcript_id=ENSMUST00000189018;transcript_support_level=NA;version=1 19 havana exon 4126 7870 . - . Parent=transcript:ENSMUST00000189018;Name=ENSMUSE00001321004;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001321004;rank=1;version=1 19 NCBI biological_region 1680 2329 . - . external_name=WI1-105F19 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 1987 2483 . - . external_name=WI1-1007O5 (end);logic_name=mouse_wi1_clones 19 . biological_region 3902 4078 0.927 - . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 5660 5977 . - . external_name=WI1-696K23 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 6506 7191 . - . external_name=BMQ-295I12 (end);logic_name=mouse_bmq_clones 19 . biological_region 6756 7552 0.999 - . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 7300 7966 . - . external_name=WI1-117B13 (start);logic_name=mouse_wi1_clones 19 cpg biological_region 7399 8022 385 . . external_name=oe %3D 1.22;logic_name=cpg 19 NCBI biological_region 7518 8056 . - . external_name=WI1-313E24 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 7731 7982 . - . external_name=WI1-1314A9 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 7848 7948 . + . external_name=WI1-2077O12 (end);logic_name=mouse_wi1_clones 19 . biological_region 8018 8788 0.991 + . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 8141 8382 . + . external_name=WI1-1876J18 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 8926 9440 . - . external_name=BMQ-392N13 (end);logic_name=mouse_bmq_clones 19 NCBI biological_region 9630 10197 . + . external_name=WI1-2307N22 (start);logic_name=mouse_wi1_clones 19 . biological_region 11478 11988 0.575 + . external_name=rank %3D 1;logic_name=firstef 19 . biological_region 11943 12004 0.676 - . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 12002 12723 . - . external_name=BMQ-71M14 (start);logic_name=mouse_bmq_clones 19 NCBI biological_region 16888 17169 . - . external_name=WI1-280E3 (end);logic_name=mouse_wi1_clones 19 . biological_region 17388 17491 0.674 + . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 17581 18347 . + . external_name=C3H-9F16 (end);logic_name=mouse_c3h_clones 19 NCBI biological_region 17771 18327 . - . external_name=WI1-1933B15 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 19523 20239 . + . external_name=RP24-131L16 (end);logic_name=mouse_rp24_clones 19 NCBI biological_region 20275 21074 . - . external_name=DN-405K5 (start);logic_name=mouse_dn_clones 19 NCBI biological_region 20481 21529 . - . external_name=B6Ng01-256O11 (end);logic_name=mouse_b6ng01_clones 19 ensembl_havana gene 20912 33289 . - . ID=gene:ENSMUSG00000024731;Name=Ms4a10;biotype=protein_coding;description=membrane-spanning 4-domains%2C subfamily A%2C member 10 [Source:MGI Symbol%3BAcc:MGI:1917076];gene_id=ENSMUSG00000024731;havana_gene=OTTMUSG00000046880;havana_version=3;logic_name=ensembl_havana_gene;version=15 19 ensembl_havana transcript 20912 33289 . - . ID=transcript:ENSMUST00000072748;Parent=gene:ENSMUSG00000024731;Name=Ms4a10-001;biotype=protein_coding;ccdsid=CCDS37919.1;havana_transcript=OTTMUST00000121552;havana_version=1;tag=basic;transcript_id=ENSMUST00000072748;transcript_support_level=1;version=12 19 ensembl_havana exon 20912 21021 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00001322403;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001322403;rank=9;version=1 19 ensembl_havana three_prime_UTR 20912 21021 . - . Parent=transcript:ENSMUST00000072748 19 ensembl_havana three_prime_UTR 21554 21576 . - . Parent=transcript:ENSMUST00000072748 19 ensembl_havana exon 21554 21692 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000621179;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00000621179;rank=8;version=1 19 ensembl_havana CDS 21577 21692 . - 2 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana exon 22655 22748 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000475077;constitutive=1;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00000475077;rank=7;version=2 19 ensembl_havana CDS 22655 22748 . - 0 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana exon 23281 23391 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000144563;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144563;rank=6;version=3 19 ensembl_havana CDS 23281 23391 . - 0 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana exon 24377 24508 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000144560;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144560;rank=5;version=3 19 ensembl_havana CDS 24377 24508 . - 0 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana exon 25687 25743 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000144566;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144566;rank=4;version=3 19 ensembl_havana CDS 25687 25743 . - 0 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana exon 26741 26860 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000144567;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144567;rank=3;version=3 19 ensembl_havana CDS 26741 26860 . - 0 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana CDS 27211 27384 . - 0 ID=CDS:ENSMUSP00000072531;Parent=transcript:ENSMUST00000072748;protein_id=ENSMUSP00000072531 19 ensembl_havana exon 27211 27406 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000223790;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSMUSE00000223790;rank=2;version=4 19 ensembl_havana five_prime_UTR 27385 27406 . - . Parent=transcript:ENSMUST00000072748 19 ensembl_havana exon 33238 33289 . - . Parent=transcript:ENSMUST00000072748;Name=ENSMUSE00000485819;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000485819;rank=1;version=4 19 ensembl_havana five_prime_UTR 33238 33289 . - . Parent=transcript:ENSMUST00000072748 19 ensembl_havana transcript 20916 33264 . - . ID=transcript:ENSMUST00000191343;Parent=gene:ENSMUSG00000024731;Name=Ms4a10-002;biotype=protein_coding;havana_transcript=OTTMUST00000121553;havana_version=1;tag=basic;transcript_id=ENSMUST00000191343;transcript_support_level=1;version=6 19 havana exon 20916 21021 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000461498;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00000461498;rank=8;version=2 19 havana three_prime_UTR 20916 21021 . - . Parent=transcript:ENSMUST00000191343 19 havana three_prime_UTR 21554 21576 . - . Parent=transcript:ENSMUST00000191343 19 havana exon 21554 21692 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000621179;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00000621179;rank=7;version=1 19 havana CDS 21577 21692 . - 2 ID=CDS:ENSMUSP00000140111;Parent=transcript:ENSMUST00000191343;protein_id=ENSMUSP00000140111 19 havana exon 22655 22748 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000475077;constitutive=1;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00000475077;rank=6;version=2 19 havana CDS 22655 22748 . - 0 ID=CDS:ENSMUSP00000140111;Parent=transcript:ENSMUST00000191343;protein_id=ENSMUSP00000140111 19 havana exon 23281 23391 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000144563;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144563;rank=5;version=3 19 havana CDS 23281 23391 . - 0 ID=CDS:ENSMUSP00000140111;Parent=transcript:ENSMUST00000191343;protein_id=ENSMUSP00000140111 19 havana exon 24377 24508 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000144560;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144560;rank=4;version=3 19 havana CDS 24377 24508 . - 0 ID=CDS:ENSMUSP00000140111;Parent=transcript:ENSMUST00000191343;protein_id=ENSMUSP00000140111 19 havana exon 25687 25743 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000144566;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144566;rank=3;version=3 19 havana CDS 25687 25743 . - 0 ID=CDS:ENSMUSP00000140111;Parent=transcript:ENSMUST00000191343;protein_id=ENSMUSP00000140111 19 havana CDS 27211 27384 . - 0 ID=CDS:ENSMUSP00000140111;Parent=transcript:ENSMUST00000191343;protein_id=ENSMUSP00000140111 19 havana exon 27211 27406 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00000223790;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSMUSE00000223790;rank=2;version=4 19 havana five_prime_UTR 27385 27406 . - . Parent=transcript:ENSMUST00000191343 19 havana exon 33238 33264 . - . Parent=transcript:ENSMUST00000191343;Name=ENSMUSE00001329679;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSMUSE00001329679;rank=1;version=1 19 havana five_prime_UTR 33238 33264 . - . Parent=transcript:ENSMUST00000191343 19 ensembl_havana transcript 20919 24475 . - . ID=transcript:ENSMUST00000190246;Parent=gene:ENSMUSG00000024731;Name=Ms4a10-003;biotype=protein_coding;havana_transcript=OTTMUST00000121554;havana_version=1;transcript_id=ENSMUST00000190246;transcript_support_level=2;version=1 19 havana three_prime_UTR 20919 21010 . - . Parent=transcript:ENSMUST00000190246 19 havana exon 20919 21021 . - . Parent=transcript:ENSMUST00000190246;Name=ENSMUSE00001326826;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSMUSE00001326826;rank=4;version=1 19 havana CDS 21011 21021 . - 2 ID=CDS:ENSMUSP00000140826;Parent=transcript:ENSMUST00000190246;protein_id=ENSMUSP00000140826 19 havana exon 22655 22748 . - . Parent=transcript:ENSMUST00000190246;Name=ENSMUSE00000475077;constitutive=1;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00000475077;rank=3;version=2 19 havana CDS 22655 22748 . - 0 ID=CDS:ENSMUSP00000140826;Parent=transcript:ENSMUST00000190246;protein_id=ENSMUSP00000140826 19 havana exon 23281 23391 . - . Parent=transcript:ENSMUST00000190246;Name=ENSMUSE00000144563;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000144563;rank=2;version=3 19 havana CDS 23281 23391 . - 0 ID=CDS:ENSMUSP00000140826;Parent=transcript:ENSMUST00000190246;protein_id=ENSMUSP00000140826 19 havana exon 24377 24475 . - . Parent=transcript:ENSMUST00000190246;Name=ENSMUSE00001319247;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00001319247;rank=1;version=1 19 havana CDS 24377 24475 . - 0 ID=CDS:ENSMUSP00000140826;Parent=transcript:ENSMUST00000190246;protein_id=ENSMUSP00000140826 19 . biological_region 21554 21688 0.557 - . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 22377 22852 . + . external_name=WI1-1152P6 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 22865 23656 . - . external_name=BMQ-248D19 (start);logic_name=mouse_bmq_clones 19 NCBI biological_region 23178 23800 . - . external_name=WI1-1627N6 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 29183 29572 . + . external_name=WI1-2424C11 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 29390 30105 . - . external_name=C3H-128L21 (end);logic_name=mouse_c3h_clones 19 NCBI biological_region 31588 31883 . - . external_name=BMQ-410J6 (start);logic_name=mouse_bmq_clones 19 NCBI biological_region 32215 32368 . + . external_name=WI1-125C8 (end);logic_name=mouse_wi1_clones 19 . biological_region 33238 33735 0.69 - . external_name=rank %3D 1;logic_name=firstef 19 NCBI biological_region 36395 36994 . + . external_name=RP23-353A20 (start);logic_name=mouse_rp23_clones 19 ensembl_havana gene 36926 51869 . - . ID=gene:ENSMUSG00000067571;Name=Ms4a15;biotype=protein_coding;description=membrane-spanning 4-domains%2C subfamily A%2C member 15 [Source:MGI Symbol%3BAcc:MGI:3617853];gene_id=ENSMUSG00000067571;havana_gene=OTTMUSG00000028408;havana_version=4;logic_name=ensembl_havana_gene;version=4 19 ensembl_havana transcript 36926 51869 . - . ID=transcript:ENSMUST00000087923;Parent=gene:ENSMUSG00000067571;Name=Ms4a15-001;biotype=protein_coding;ccdsid=CCDS29594.1;havana_transcript=OTTMUST00000070387;havana_version=1;tag=basic;transcript_id=ENSMUST00000087923;transcript_support_level=1;version=3 19 ensembl_havana three_prime_UTR 36926 37827 . - . Parent=transcript:ENSMUST00000087923 19 ensembl_havana exon 36926 37944 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00000548926;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSMUSE00000548926;rank=7;version=2 19 ensembl_havana CDS 37828 37944 . - 0 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana exon 38718 38831 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00000548927;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000548927;rank=6;version=1 19 ensembl_havana CDS 38718 38831 . - 0 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana exon 39189 39281 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00000548928;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000548928;rank=5;version=1 19 ensembl_havana CDS 39189 39281 . - 0 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana exon 39912 39968 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00000548929;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00000548929;rank=4;version=1 19 ensembl_havana CDS 39912 39968 . - 0 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana exon 41792 41914 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00001370695;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00001370695;rank=3;version=1 19 ensembl_havana CDS 41792 41914 . - 0 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana exon 43289 43463 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00000621169;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00000621169;rank=2;version=1 19 ensembl_havana CDS 43289 43463 . - 1 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana CDS 51738 51796 . - 0 ID=CDS:ENSMUSP00000085234;Parent=transcript:ENSMUST00000087923;protein_id=ENSMUSP00000085234 19 ensembl_havana exon 51738 51869 . - . Parent=transcript:ENSMUST00000087923;Name=ENSMUSE00000621170;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSMUSE00000621170;rank=1;version=1 19 ensembl_havana five_prime_UTR 51797 51869 . - . Parent=transcript:ENSMUST00000087923 19 ensembl_havana transcript 41792 51800 . - . ID=transcript:ENSMUST00000145110;Parent=gene:ENSMUSG00000067571;Name=Ms4a15-003;biotype=protein_coding;havana_transcript=OTTMUST00000070389;havana_version=3;transcript_id=ENSMUST00000145110;transcript_support_level=3;version=2 19 havana exon 41792 41914 . - . Parent=transcript:ENSMUST00000145110;Name=ENSMUSE00001370695;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSMUSE00001370695;rank=3;version=1 19 havana CDS 41792 41914 . - 0 ID=CDS:ENSMUSP00000117513;Parent=transcript:ENSMUST00000145110;protein_id=ENSMUSP00000117513 19 havana exon 43289 43493 . - . Parent=transcript:ENSMUST00000145110;Name=ENSMUSE00000783205;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSMUSE00000783205;rank=2;version=1 19 havana CDS 43289 43493 . - 1 ID=CDS:ENSMUSP00000117513;Parent=transcript:ENSMUST00000145110;protein_id=ENSMUSP00000117513 19 havana CDS 51738 51796 . - 0 ID=CDS:ENSMUSP00000117513;Parent=transcript:ENSMUST00000145110;protein_id=ENSMUSP00000117513 19 havana exon 51738 51800 . - . Parent=transcript:ENSMUST00000145110;Name=ENSMUSE00000724007;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSMUSE00000724007;rank=1;version=1 19 havana five_prime_UTR 51797 51800 . - . Parent=transcript:ENSMUST00000145110 19 ensembl_havana transcript 41878 51849 . - . ID=transcript:ENSMUST00000144485;Parent=gene:ENSMUSG00000067571;Name=Ms4a15-002;biotype=protein_coding;havana_transcript=OTTMUST00000070388;havana_version=2;transcript_id=ENSMUST00000144485;transcript_support_level=5;version=1 19 havana exon 41878 41914 . - . Parent=transcript:ENSMUST00000144485;Name=ENSMUSE00000805889;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSMUSE00000805889;rank=3;version=1 19 havana CDS 41878 41914 . - 0 ID=CDS:ENSMUSP00000115600;Parent=transcript:ENSMUST00000144485;protein_id=ENSMUSP00000115600 19 havana exon 43289 43527 . - . Parent=transcript:ENSMUST00000144485;Name=ENSMUSE00000794238;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSMUSE00000794238;rank=2;version=1 19 havana CDS 43289 43527 . - 2 ID=CDS:ENSMUSP00000115600;Parent=transcript:ENSMUST00000144485;protein_id=ENSMUSP00000115600 19 havana CDS 51738 51807 . - 0 ID=CDS:ENSMUSP00000115600;Parent=transcript:ENSMUST00000144485;protein_id=ENSMUSP00000115600 19 havana exon 51738 51849 . - . Parent=transcript:ENSMUST00000144485;Name=ENSMUSE00000824631;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSMUSE00000824631;rank=1;version=1 19 havana five_prime_UTR 51808 51849 . - . Parent=transcript:ENSMUST00000144485 19 NCBI biological_region 37094 37707 . - . external_name=WI1-133G23 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 37725 37977 . - . external_name=WI1-397N12 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 42233 42994 . - . external_name=RP24-339A14 (end);logic_name=mouse_rp24_clones 19 NCBI biological_region 42300 43005 . - . external_name=DN-52G14 (start);logic_name=mouse_dn_clones 19 NCBI biological_region 42393 43162 . - . external_name=CH29-21N11 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 42403 43162 . - . external_name=CH29-2B8 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 42410 43064 . - . external_name=CH29-11P15 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 42483 43165 . - . external_name=MSMg01-521A2 (start);logic_name=mouse_msmg01_clones 19 NCBI biological_region 43894 44280 . + . external_name=WI1-435J22 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 46639 47362 . + . external_name=BMQ-428N13 (start);logic_name=mouse_bmq_clones 19 NCBI biological_region 47574 47857 . - . external_name=WI1-2077O12 (start);logic_name=mouse_wi1_clones 19 NCBI biological_region 47638 48140 . - . external_name=WI1-1876J18 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 47855 48555 . - . external_name=DN-502K5 (end);logic_name=mouse_dn_clones 19 NCBI biological_region 48566 49270 . + . external_name=MSMg01-541P14 (start);logic_name=mouse_msmg01_clones 19 NCBI biological_region 48724 49215 . + . external_name=WI1-720B7 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 48742 49372 . + . external_name=CH29-188O20 (start);logic_name=mouse_ch29_clones 19 NCBI biological_region 50361 50925 . - . external_name=WI1-2307N22 (end);logic_name=mouse_wi1_clones 19 NCBI biological_region 50410 51049 . - . external_name=BMQ-462N10 (start);logic_name=mouse_bmq_clones 19 NCBI biological_region 51035 51373 . - . external_name=C3H-76I18 (start);logic_name=mouse_c3h_clones 19 . biological_region 51233 51623 0.836 + . external_name=rank %3D 1;logic_name=firstef 19 . biological_region 51738 51942 0.947 - . external_name=rank %3D 1;logic_name=firstef bcftools-1.21/test/csq/ENSMUST00000133836/filter-problem.1.cmd000066400000000000000000000002711467060157400230040ustar00rootroot00000000000000{bin}/bcftools csq -f ENSMUST00000133836.fa -g ENSMUST00000133836.gff filter-problem.vcf -i 'FILTER="PASS"' --phase m | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENSMUST00000133836/filter-problem.1.cmd.out000066400000000000000000000002261467060157400236120ustar00rootroot000000000000007367 T A synonymous|Ccdc86|ENSMUST00000025639|protein_coding|-|162P|7367T>A 40512 CCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT CCTCTCTCTCTCTCTCTCTCTCT . bcftools-1.21/test/csq/ENSMUST00000133836/filter-problem.vcf000066400000000000000000000004331467060157400226600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FILTER==30 && AD[*:1]>=25"> #CHROM POS ID REF ALT QUAL FILTER INFO 19 7367 . T A . PASS . 19 40512 . CCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT CCTCTCTCTCTCTCTCTCTCTCT . LowQual . bcftools-1.21/test/csq/ENST00000000000/000077500000000000000000000000001467060157400166205ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000000000/ENST00000000000.fa000066400000000000000000000301761467060157400207300ustar00rootroot00000000000000>I I:4457276-4469464 CACAGGTTCACAACGGAGCAGACTTGCTGCCTCTTCTCTGAAAATAATTTTCGCCGCATT TTTTTATTTTTCAAATAAAAACATCTATTTAAATTATTTGTTTTCAGGTAAAAATATGAC CGATAAGGAGAATTTCTACTCGGGATTCTTTCTTGGACGACTGCCAGGCTCATTTGACAG CCGATTTTTGATTAAAGTCGCCTGTTTTCAGCCCGGAAAAGAGGAAAGAAATGTTTTTGA GCTTACAACAGATACAAAGAGAGAAGAAGATTATGGAGAAATGGTGCATTTTTGGGTAGA GTAAGTTTATTTTCATTTTTCTAAAGTTCTAAAAATTAATTATTTCTTTTATAAATTCTA TTTTTCAGCAAAGGACCTCTCCAGAACAAGTCATTCGTCCGGTTTGAAGAGAATTACGAG ACTTTTTTTATTCATGAGAATAAGATGTTTGACAGAATCGTGGTGAGCTACAATAAGAGC TTAAAAACTGAAAATAATCGATTAATTTCCAGCATACGGATAAAGATTTTTATGTTGGAG TCAACGACCTTCCAGATTCAGATATCTACATACATCCAGATTTAGGAAAAATGATTGATA CCCGTTCAATTGTGACGCCGGGAAAGTATGTTGAAAATATTCGCTTTTACAACGAATTGC AATGAAAATTTCAGGAAATACAACTTTATCACTTTCGAGGTCAAACAGAATGAAAACAAT AGTTTTGATATTGAAATTGTTGGTGGAGAAGTTCAGGGAAAAGAAAAGAATTCTGAAGAG CCATCTGCCAAGGAAAAAATAATTCAAAAAATGGAACAAGTTCATGAAGTGATGAAAGTA GAGTATGAGTACAATAAAAATGTGAGTGTTTTCAGTGAAAAAATTTAAAAAATTAAAAAA TTCGGTAATTTATTCAGGAAGAAACCGCGAATTGGGATGTAATCGGACATTTGAAACTCA TCAAATTTTATGACAAAGATCTCACATCTGGGCTTCGTCCTGTACTACGGCTTATGGATA ATAGACACGTTGCGTTGTTCAAGAAGCAGAGAGAAAGTAATAAAAATGAATATTTATTTT ATTTAAAATGAAATAATAATTTACAGCCATGCCAATCAAGATGATCAAAGTGATTGAAGT AGACGGAATTTGGAAGGATGATGTTAATTTCGTACCGCAAGAAGGTACACTTCTTCCTAC AGATCATGATGAAGTTTGTTCTGTTTTACAGATAATTTTAAGCATCAATTTTTTTCAGAA AACCGTCGTCCTATTGGGAAATGATTACCGTCATAAATTCGAACGTTTGTTCAAACGTGA AGACGTGTTCAGATTGGAATCCAATAATACGCTTACGCATCTTAAATTCTGGCAGTACGG TTTAGAAAAAATCTAAATTTCTATTTAAAAAAAAATTGTAAATTGGATTTTTTTTTTCAA AGAAAATCGAAAAAATTGAAAAAAAAAGTTTAGAAAATTAACCAAAAAAAAAAACAATTT TTTGTTGATATTGATTTTAAAAAAACATGAGAAAACAAATAATTTTATTTTCTGAAAAGT AGAACAATATCCAAATTTCTAAGCGTTTTTTGTTGAAAAATAAAAAACAAAAAAACGAAT ATTTCGATTTTTTCAAAGAAAATCGAAAAACCAAAAAAAAATTAGAAATTAGCAACAAAA AAACAAATACATTTTAATCAAATTTTGTTCATGTTGAAGGTCATGTTGGTGTTGAAAAAC AAATAATATTTTCTCAATAAATTCAATTTTTTTGTTGAAAAAAACAAAAACTAAATTTTA GATTTTTAAAAATTTTGAATATCGAAAAACCGACACCCTTGACTACCATTATATATTATT CTAAGTTTTCCTAAAATGATTTCCAAAAAGTGTATTATAGATTGCACTAAATAATTGAAT TTTTCGCTATTCTTAGTAGTATGTAATCTTTGACGCTGGTGCAGTCTCCGACCCACTTTT TTGACAAGTCAAAAAACTCCCAGAGTCAAAGATTACATACTACTTAAGCTCCAAATATAC CCAAAACTCCCTGTTTAAAAATTCTCATTTTCTCCAAATCTCCCTATCATACATAGTAGT CAAGCTTCGACCCACTTTTTCAAAATTTTAAAACAATCATTTTTTAAAGAAAAATTAAAC TTTTAGTTACATTTACTCATTTTTCAAAATCTTAAAAAGTAACCATTTTTACCTATATCA AAAATTTCAAAAATCTAAAACATAAAAAATACCCCCTGCTTTCACCTTCACCAAAAATTT TTCATAATCATCATATACAAGCCAACTGATAAGACTCCCCACTTCTTAACCAACTCCAAG AATTTCTTATCAGCTTCTATCATAGTCAAGTGGTAGTGTGCCTGTCTTGAAAACTTAACA CAAAAGTTTGACTCCACACACAAACTTGGATCAAATGAGCTAAAGAGATCTCATTACCTC TCAAAATATGCAAGAAAAATCGAGAAAAAAAAATTCGAGAAAAAAAATGGAAAAATTCTC GAGAAAAACAAAATCTCGGTGGGGAACTCAGTGGACAGCAGTACAAGATGACACACCATT CTCTTATCGCTTACTCAACCTGAATGCCACTGTGTCTGACCAACACCTTTCTTATCAATT AATTTTCTTCTCTTTTAAGGCGCGCACTTTTTTGTTCTAAACAAAATGTATTTTTGGGAA AAAAGTGGCAAATTTTCAAATAGGCAACAAATTTATTTATTCTCAGAGAATGAAATATAT TTTTTTAAACTATTAATAGTTTTTGAATTCTGTCTGCACCCTCCTCTCTTCACACACTCT TTCTCACAGGTTCACAACGGAGCAGACTTGCTGCCTCTTCATCATCGTCATCAATCTCCA ACCAATACGAACTTCGCTTTAGGGAAATGTGTAGCGAGTCCTCCGATCTTGATCATTGGA ATTTGTGAAGCTTCGTCGAGCATCACCAATCCAATCTCATTCGCTTTGCTGGCGAATCCA ATATCATTGAGAGCTGTGTGAATCGATGCTGTAGTCCCGATGATGATTGCTGTCTCATGA ATCTTCATCAACGCCGTCCAGATGGTATGTGCTGGGGGCTCCGTTTTGTATGGTGCTTTG CATCGAACTCTAATCTCGTTGTTCAACATCGGCGACGGAAGAAGTCCATGAGCGTTCAAA TGTCTCGCGGCGTCAATAATTGCAGGATGGGTTCCTCTGACATTCGGTCTGTTGACTGAC TGCACGACCTCCGTGAACACTTCTCTCCATAGAATCGGGAAATCATCCTCTGTGAGCACT TCCGGCTTCGCCTCATCTCTCAAACGCGCTGACATGGCTCGAACAACCTTCACTCTTCCT CTGGGTGCCAACGAACGAATCGCATCATGAATTGCCTTCACTGCTCCATTGTTGTTCGCT GAAATAATAACTCTTTGGATATTTTGATTTGAAAATTCGATAGCTGTTGCAGCTACCGCC TTGGTTTTACCCGTGCCAAAGGCACCATCCAATGATAAAGCTCCGAGCTTCAGGTCGCAA CAAGCTTGAATGAACGTGCTCTGTTGAGCTGAACACACGAAGTTCTGATATCTGAACTCC TTATGTGGATAGTTTAAGCCATTACTTGCTATGATTGGACCACCATTTAACGCTGCAAAG GTTGCCAAACCTTTATTACGATCCAACACCGTATCCACTGGAACAACAGGAGTTGCTGCT AGAAGGTGACCATCTGCTTCTTTAGTTTGTTTTATAAGGACTGCGTCCTCTCCGACCGCC AAAATGTGAACTGCATTATCGGCCGGTCTCAGAATTCTGCACTCGATCGTGGTGATCGCA TCCGTCGACTGCACCGCGTGATCGACCGCTGCTGGCACGAAGGTTCCGGCTGGTGTTTCG ATCGAGAATTTGGTACCATTCTTCCAATTGCACGCCTTGACTGGCCTTCCAGGATATTGA AGAGCAAAAGAAACCTTCATTGATCCTTCCAATTCACGTACGTGTTGCAACGTAGTTTCG TAGTGGAATTTGTCCTGGTTCATATTCGAAGTGCTGATCATGGCGCTCAATCCATGATGT CCGAGTTTCCGCACTCCTCTCCAAGCATCTTCTGTATTCGGCGATCTTCCTGCCATGTAG TTTGGAAGATGAAGAAATGGGTAGGCTTTCCTTGCTCCCATGATTCCGAAGTTGATGACT TGTGGACGAAGATCCCATGACTTACTTTGAGCTGCAGTTTCTCTTCTCACCACAATGTGT GGCGTTCCAGGCAACAGTGACTTCAGGAGTTGTCCAGGAATGAGCACAGGTGTAAACGCT ACTGCATCAGCTCGGTATCCTTGAGGTGCACGGTTATCGTTGAAAGTGTCCTCGCTTACC GTCACGATCTCTGTGACTCCGCAGACAGCTAACTTCTTACTGTGACGACCTCCTGCTGCT CTGCCAACCAACGAAAATGGTTGAGGTTCTGAAATTTTTCTTTGTACCAATGAAAACTCA CTTACCTGCCAATAGTTGTGGGCTTTCATGTTCCTAATCTGATCGAACGTCTTCATAAAC GACTCCGGTGCAACATCTCTTCTCTTGACAACCTTGTGGATCATGATCGTGTCTCCCTTA TAGTATTGCTTCAATTCGGCATACTTCCTTGACGTCACATCGTACGACCACTTCGTAAAG TTCATGTACATCAGATCCGGACGATCGTTCGCCACAACCTCTTTGAAAACCATAGCTACT TTGTAGACTGTTCCATTGTTCTCGACAATTGTAGCCAATGCATGCGGCTCGCTCGGAAGC TTCGTGATGAAATTAAGAGACAACTCCACCATTGTGTTTGGCGGTTTATCTTCATGTAGT GCTGGACGATGAATCTCTCCTGCCGTGTAGTTCCTGAACGACTGCACATCCTCCAATGTT GTCTCAGCTGCAAGCCTCTTCGCCACCGAAATCTTCGGCTCAAGATCCGGTTGAGCTCCA TAGTGTTCTCTGAATGGATGATGTCTCTGCGGCGCTGGTCCTTGAATTTCCAAAAATTCA AATTCGTGTTCCTTATTATCTTGGTCTTCTTCAACCATCTCGGCCCAGGGACGTCTCTGC ATTCTCAAGAATCTCATATTATTCGGCACGCGTTCGCGTTCTTGTTCATTATCGTGATTA TTATTGTTTAAGTTGATAGGAATTTGGTTTTGAGGGGGAAGAATGGGAACATTCGGAGCC CCGCCTGCTCCAGCGGCGAGCACAGGTGACCCTGGTCCTTCCGCTTTTACAGGTGGGTAA ACTTCTCCGATGTTGGCTGCTTGTCCTCTATTCGCTTCAGCTTGTCCTTCAACAACATTC GCCGGCGGCTCCACTGCTTCAGGCATCTCTTCATCACGATTGACGGGCTCAAGCGGGTCG GCGCCGTCATCTTTTCCACGATCCGACATCGTCTCACTTCACAAAGGTTGGTTGGTTGAT TTGATTGGTGTGTAGATTCTGAAATTAATAAAATATTATTTCGACATCGTAAAAAAAATA CGAAAACAAACACCAAAACAAAATACGTGGAAAGATAAAATCTATTCCTACTACGTGGCT TGTGACTCACTAAGGTCACCTACGTGTTACGCCTACGTGTTACGCCTACGTGCTACATTA ATTGATTAAATTCCTAAAATGCTAACGAAACGAGGAAAATAATAATTAAAACGCGACAAT TTTACGAAATTTTCCTAAATTTAGATAAAATCCTAAATTTTTACGCTGAAATATGCCTAA TAGTAGTGTAAAGTTGCGCTGGGACTTCTAAATCGCTAAAATTACCTACAAAAACTGCAT AAAATGATGCGAAAAGCCGAAAAAGCTGCGAAAAAGCGTCAAAAACAAACAAAAACAACC CGAGGGCCCAAAAATTTGAATTTGTTTTGACAAAAACACGCGCGCTTACGATCGCTTTCG CTTCGAGACCCGACGCGTCCCAAGACCCATTCTACGTGAAAGTCTATGCGCCTTTAAGCT AAAATCTCAATGCGAGCTAATTTTCTACGATTTACGAGCGCTCGGGAATTATTTAATTAA TTTCTTCAGAAATGTTGTGTTTTTATGGGAAAATAAACATTTTTAATTAATAATTTTACG TTTAATTTTTTTAAAATCGAAATACGGGTAATTGTTCGTATTTAATCAATTGATATTCCA GAACAAGGAAAGTTACAGCGGTTGCGGGACACATCACACTTCGAATACGCTCAGAACTGG AAAGAAAACAATGTTACCGGGCAAATAGACGTCGGAATTGATTAAATATGTGGTAAAAAT GAACAGCATTGTGGAAATTTACTACTGACGAGCTCGCGGTTTCCATCACGCTTTCATTTC ACAATTAAATCATAATTTTGAATTTTGACAAATTGGCAATTTGCCGGAATTTTTGAATTC CGGCAATTTGCCAATTTGCCGGAAATTTTGAATTCCGGCAAATTGGCATTTTCCGGAAAA AATCGTTTGCGCGCACCCCTGATTTGCAACGCTCATAGGTACATTTTGGTAAATTTAAGG CAGAAAAAGAGGAAAAAATAAAATTTCGTGATTCCTGGATGTCAGCGAACCGTGAGAAGA AGAAGTTGGAGACTGTGATCAAAAATCTTGAGAAAAAAATTGAAGATCAAAAGGCAAACG CAGGAACTAAAAAGAAAGAAGCGGAGCAAAAAGAAAATCTTCGAATTGAGCAAGAAAAAA TTAAGAAAAAGAAGGAGCAAGAAAGATTGGAAGTCCCACCTACACCTTTTGATGATCTCA ATAGTCAGAGTGCAAAAACTTTAAGAGTTGAAAAAGCAATAGAGAATTTGAAATTTCTAG GTATGGAAAAATACAGTAATATAGAACATATTTCGTTTTCAGGCGGAAAAAGCACCGAGT TTTATCGACGAGTTATAGGAAGGTTGGGAAAGTCAGGATTGTTCAAATGGAAGATGTCGA AGAGAGAAGGATTTTACCTCTATCATGCATGTGGTCTAACCCGAAGAAAGCTGCGCACGC TGAAGGCACATTTTAGTAAATCCGGATGTTCTGATCCATTCCCTTCTGTTCACGAAATTA TGAAAATTGAGAAGATCGTGGGTGCAGGCGAACAATTTTCCGTGACTGAGCACGATAAGG ACGGCGAGGAGGTGGTGGCAGCGCATCTAGTCGATGTTATCAAATATCTCACGGACAGGA TCCATCACTTGATTGATAATGGGAACCTGGTCATCGGTACTGATCCAATCTGGCTCACCA TTCTAGGTGATAAAGGATCAGACGAGTTCAAGCTGTGCCTCTCTATAGGTAACGCCAAAA ATCCGAACAGTTGTTGTCATTTGATCCCGCTCGGCATTTTCAACGATGACGAAAAGTCTT CTAACATCTCGAATGACCTTACTCCGATCGTGGCACAGCTCAATAGCCTCAAAGAGCTGA AACTGAAAGTAGCCGGGACCGACGTCACTGTGCCAGTCCAGCAGTTTCTTGGTGGGGACA TGAAGTTCCAGTACGATGTCCTGGGCCACCAAGGAGCTTCTAGTCAGTTTCATTGTATGT TCTGCAACTCGCTGAAAAGTCGGTTAATCGGTGGCTACATTCGGGGAGCAAATGTTACAC TTAGGACAGCTGCCAGCTACAAGGAGAACAGTGGCAAAGATGGGAACAATTACGCCAGAA AAAAGTCAGTTTCTATTCGATCTCGTCAATCTACAAAATGTGATCCCCGAAGCTTGCATA CCCTAATGGGCTTAGCCCAACGCTTTGGCTTTGATTACTTAATACTATGGGCGGCGAGAA TTGACAATCCAACTCTCACTTTGACCAAAACCGATATCAAACGAAGCAAAATTTCTAAAG GTCGCCTGAATCAACTACAAGAAAGTCTGAAGAAATTGGAGAAGGTGGTGTCAGGAATGG AAACTGTGCAGCAGGTTTTTCAGAACTACAAGAATAAACGCGTTGATGGGAGATCGTGTG GTGAAACTTGCCATGCTTCTATCTGTCTTTTTAAAGATAAGAAGATGAAGTCAGCGAAGG GTTACGACGGGCGCAAGGTGGAGTGCAACACTTGCTTTCAGGCAGTTCATGCTGTGTGTG GCGGTCTTTGGACACTCGATGACTGGGAACTAACCATTTCTATTTTTCGTGTAACAATCT ATTTTTCGTGTAACAATCTATTTTTCGTGTAACAATCTATTTTTCGTGTAACAATTAATT TTTCGTGTAACAATCAATTTTTCGTGTAACAATCTATTTTTCGTGTAACAATCTATTTTT CGTGTAACAATCTATTTTTTCGTGTAACAATACATTCAATCTTTTCAATTTTTCAAAAAT CAAAGAAACGGGCAAATCACACTTGAGTAAAATTTTTTTACAGCTATATTTGGCGATTAG GATATATTTTCTGTCATTTATAAACCAACAATGGTTTTTTTACTGAACAACTTATTTTAC AGGAGAATAACCGGCACCTAAACGAGTTGAGAAGTGACTTACGGGAGAAGAAGAGTGTTA TATTCAGTCAAGGCTTGAAGATTGATATGTTGGAATCCCAACTTAGTCAACGTCAGACAG AATTTGAATACCGATCTGCCAATGCAGCCGCAAATTCTTTCACAAGAAAAGGTTTGTGTT GCAATATTGTTCAACGAACATACCCCGATTTTCAGATCACGGAAAACTCTACCATTGCTT CGATATTAAGAACCAGGATTCGACGTCTGTAAGGTAAGCATTTTGGCATTTCAAGTATGG ACAATAGCAATTTAATTAAATGATTATTTGTGAAGATGATTAAAATTATTAGAAAAACTA CCGTCTTGGTTGAGAAAAAACTGATACGGGTAGAACCAACTTCCCAGAGGGAATTACACA ATTGTATCGGTACCAGATATTTCCGTTATTATTGTTTAATTATATTAACATATTTGCAGC GATACCATGACATGTCGGTGCTCAATGAAGCCCTGTGTTTTCTACTTGGACAGCCTCCCT GCGGCCAAAACGCCGTCTCTGACGCAACTTCGTAGAATTGTCGTTCTTATGCAACAAAAA CCTTCACAAAAGATCGATCCGAAGGAGATGTTGTTGATGACATCCATGCATCTTCCTTTC CCGATGCAAGAACCATCTACCGAATATTTTAACGCGATTTCCGGATGCTCGACTTCGTAT ATTTGTGTGGAAGAAATGGGGATCGGCTTCTCATTCCGACGACACGTGGAAAAATTGTGG ATGAAGAACTTACCTCCGGCGACCAATGGAACAGATAAAGCTGCCAATGATTTGAAAAAT CAGCTCAAAGTTAGAAGGAATGTAGGCAAGCACGATAGAACAAGTCGATACGCACGAAAA TCGCATAATTAAACATTCCCGTCTTCCTGTTCTGTTGCCATTTACAAAAAATTTTTTCCC AAATGATCGCCCGCGTCGTCATCTGTTTCTTTTTTCCAATTCAATTTTATATTATCCCCC GTATGTTAATCATCAGAAAAGTACAATAATTTCTCAATGTGAAAATGTTTATTTCTTCCG GCCTCTTCCCCAATTGTTTTTTTTAGTTGTTTTTTTCAATACGAATTTTCTAATAGTTAA AGTGGTTCAGAGATTAATCACAACAAAATAAAAGAATTTTCACTAATGGGGATTCGAACC AACAACCTTCTGACTACAAGGCGAGGGTTTTACCACTTGGCCATTGCGCGCGCGCCGCCT CTTACTCTGCGTGCGCGCCTCTCCATTTTTACAGCAGCCGACACCTCCGAAGGACCTTGC CTCGGCTCCTGCCTTCCCGCCCCTTCCTGCTCCGCGAGCCCACACCACCTCAAACTTTAA TCGCTCATATCTCAGCTCAAAACCATCGCAGAGACTTCGTTCTTCAAGCAATCGATCCCA AATTCCAAGGAGATTTCGATATAACCCCATCTCAGGTTCGAGGCGAAGCCGAGAACCTGC GCAAGGTACTTTTTCGGGCACACCCAATACCCGAAGGGCTGGCGCGGCTCCGCCGCGCTA GTCTATTCAACTTTAAAGCATGTAATGTGTTTGAAATGTATACGAAAAAAAAGAAAACTT GATTTTTATTTATTTGTTTTATTTTATGAATAAATATTTTAACAAACATCTCCTCTGTTG CAACTTGTTTTGTAGGATCCTATTAAATGAATTTCATTTCATTCGTAATTTTGAAAGTGA GCGGAAACATTCTTCTTTTAACAAAAAACGTTCACTTGTGTTCACGTTTTGTTCTCGAGA TCTTCCAATATGATTTGTTTCGTACTCCGTACATCAAGAAGAATGAGAAATTTCAAATCC ACATCACTGAAAAATTTAGATAAAATTAAAAATAAAAATCATCAAAAAGAAAACTCACCG TCAAAGCTACAAGTGTGCAGTGATTCTCATTGCTAGGCATTTCCAATCATCTAAATAGCA TTGCCTGCCCATAAAAGAATAGAAGGAAGCACCAAAGTGTCATTTTTGTTCGTAAAAACT GGGTGTACATTCAAAAAGTCTTGTATAGCTTAGCTAAGCTCTTCATCTAAAAGCATTGGC TTCATCTTTTCACTCGTCATTCCTCTCAACAACTCCACAACAGTAAAGTCATGCCCTTCG TTCATTAGTCAATTCGTTGAAGTCTATTAGTCTTTCGAAAGAAACGAAATCATTCCATTT CACTAAATTTGACGTCACCAACTGTCTTCATACTCCTCAAAACTCCGCCCCGTGTGTTGT GCTGAACCGTTGCCACGGGTTACTCTGGATACAGAAACATCTGCTCTTAACTAATCTACC TTTTGCGTTTCTCTGTGCCAATTTTAGATTGAAAACTGCTCACATGACATTTTTCTCCAT TTTGCTTTTATTCTGTGCAATGGTGGTTATGATGAGCAAAGTTTCCGCTATCGGACGACG AGAGGTGAGAATTTGTATTTGAAACATCTCATCGGGTTTTGGCCGAAACTTCTTGACCAA GTTTTTCCAAAAATAACTTGGTTCAGAAATGCCAATTGGCCAACCTTTGTCTAGGTCTAC TGTTATTCAAATCTGAAACAAGTATTGTCAATTTTTACCCAAGTTTTTACGGCCAGTAGA AACGTTTTGATGAAAATTGGATGAACCTTAGCGCTGCCTAAACAATGTCGTACCAACTTC GGAACCACGTTAACACTTTTGGACCGTACGAGAAGGCCAAATTCCAAAAACTTTGAATTT TTTAAAATTTCACACTTACTTTACCCCTATTTATTGTAAAGATTGATATATTGATGGGGG TGAGGGGTCCTATATTTTTAATTTTAATTTTCATACTACAACAAGCTTTATTGATAAAGC TCTCGTAAATAGTAGTATGTCATGCCTTAGATCTACAGTAATAAATGAAATATCAAATTA ATGTCGAGGTACTGTAGGAGTTTTTCTATCCAAAAAAAAACCTAACAGTTCAATTCTTTA AAATCGATTTTGCAATAATTTGAGAATTCGTGAACTTAATTCAACTTAACTTATTCAACT GTATAACTTTTAACTTTCCACTTTTAAACTTATTTCAGTGAGAATGCACAGTTAATTTTT TTATAGGTGGGGCATTTCAGCCTTGACCGCGTGGATTGTCCAAACTTATAAAAAACTTTA AAAATAACAGCAACTATTTATTTTTGAGAAGGTGATATAATCGATAATAACTGAAATTAG TTAATAAAAAGTTTCCTGGGGATTTATTCGATGAACCAAATGAGTATTGAATTTTTGCAT TTCTTTTATACCTGCGTTTCTTTCTTGCAAAATCAAGTTGTTCTGATTGATATAATTTCC TTAAGGATAATTATAATTATTTCAAAATTATTTATTAAAATTCCAGGAAAACGGCATGCC ATTCGAAACTCGAACTCTTCGCCCATTTCCCCAAATGACAGACTCGGAAGATGACAGCAC TAAAACTCAAGTAATGGTTGTTCTGCTGGTTGGATTCTGTGTTAGTCTTGCCATTACTGT CATCATCCGATTCCTTCGAAAGTATTCTGAACGACAACGTCTCTATTCGAGCTTCAACTG ATACCATTATTCTGACAAATACTCTTTTGGCACATCTCTCTTTCTCTCTTTAATTCGCAG TCTCTCATACTTTATATCCAATTACATTTTACTTTTATTATGTGCAATAAAGAAAATTTG ATTAACAAT bcftools-1.21/test/csq/ENST00000000000/ENST00000000000.fa.fai000066400000000000000000000000211467060157400214500ustar00rootroot00000000000000I 12189 21 60 61 bcftools-1.21/test/csq/ENST00000000000/ENST00000000000.gff000066400000000000000000002145231467060157400211040ustar00rootroot00000000000000I WormBase gene 100 12186 . + . ID=gene:WBGene00016561;Name=WBGene00016561;locus=eri-6;sequence_name=C41D11.1;biotype=protein_coding;so_term_name=protein_coding_gene;curie=WB:WBGene00016561;Alias=eri-6,C41D11.1 I WormBase mRNA 100 1462 . + . ID=transcript:C41D11.1a.2;Parent=gene:WBGene00016561;Name=C41D11.1a.2;wormpep=CE08658;locus=eri-6;biotype=protein_coding I WormBase five_prime_UTR 100 115 . + . Parent=transcript:C41D11.1a.2 I WormBase exon 100 300 . + . Parent=transcript:C41D11.1a.2 I WormBase mRNA 102 12183 . + . ID=transcript:C41D11.1d.1;Parent=gene:WBGene00016561;Name=C41D11.1d.1;wormpep=CE43795;locus=eri-6;biotype=protein_coding I WormBase exon 102 300 . + . Parent=transcript:C41D11.1d.1 I WormBase five_prime_UTR 102 115 . + . Parent=transcript:C41D11.1d.1 I WormBase mRNA 102 12186 . + . ID=transcript:C41D11.1d.2;Parent=gene:WBGene00016561;Name=C41D11.1d.2;wormpep=CE43795;locus=eri-6;biotype=protein_coding I WormBase exon 102 300 . + . Parent=transcript:C41D11.1d.2 I WormBase five_prime_UTR 102 115 . + . Parent=transcript:C41D11.1d.2 I WormBase mRNA 106 4001 . + . ID=transcript:C41D11.1b.1;Parent=gene:WBGene00016561;Name=C41D11.1b.1;wormpep=CE43749;locus=eri-6;biotype=protein_coding I WormBase five_prime_UTR 106 115 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 106 300 . + . Parent=transcript:C41D11.1b.1 I WormBase mRNA 106 9646 . + . ID=transcript:C41D11.1f.1;Parent=gene:WBGene00016561;Name=C41D11.1f.1;wormpep=CE43740;locus=eri-6;biotype=protein_coding I WormBase exon 106 300 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 106 300 . + . Parent=transcript:C41D11.1f.1 I WormBase mRNA 106 9646 . + . ID=transcript:C41D11.1f.2;Parent=gene:WBGene00016561;Name=C41D11.1f.2;wormpep=CE43740;locus=eri-6;biotype=protein_coding I WormBase five_prime_UTR 106 300 . + . Parent=transcript:C41D11.1f.2 I WormBase exon 106 300 . + . Parent=transcript:C41D11.1f.2 I WormBase mRNA 108 9611 . + . ID=transcript:C41D11.1b.2;Parent=gene:WBGene00016561;Name=C41D11.1b.2;wormpep=CE43749;locus=eri-6;biotype=protein_coding I WormBase exon 108 300 . + . Parent=transcript:C41D11.1b.2 I WormBase five_prime_UTR 108 115 . + . Parent=transcript:C41D11.1b.2 I WormBase mRNA 108 12186 . + . ID=transcript:C41D11.1a.1;Parent=gene:WBGene00016561;Name=C41D11.1a.1;wormpep=CE08658;locus=eri-6;biotype=protein_coding I WormBase exon 108 300 . + . Parent=transcript:C41D11.1a.1 I WormBase five_prime_UTR 108 115 . + . Parent=transcript:C41D11.1a.1 I WormBase mRNA 116 9441 . + . ID=transcript:C41D11.1c.1;Parent=gene:WBGene00016561;Name=C41D11.1c.1;wormpep=CE43808;locus=eri-6;biotype=protein_coding I WormBase exon 116 300 . + . Parent=transcript:C41D11.1c.1 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 116 300 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 301 368 . + . Parent=transcript:C41D11.1a.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1a.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 301 368 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 369 459 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 369 459 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1a.2 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 369 462 . + . Parent=transcript:C41D11.1f.2 I WormBase five_prime_UTR 369 462 . + . Parent=transcript:C41D11.1f.2 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 369 462 . + 1 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 460 512 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1a.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1a.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase intron 463 512 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g5_i1 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B Confirmed_EST L4_Nanopore_Roach_62270 %3B I WormBase exon 513 625 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1a.2 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 513 625 . + . Parent=transcript:C41D11.1f.2 I WormBase five_prime_UTR 513 625 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 513 625 . + . Parent=transcript:C41D11.1f.2 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 513 625 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 626 674 . + . Parent=transcript:C41D11.1a.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1a.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 626 674 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST OSTF079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 675 861 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1a.2 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 675 861 . + . Parent=transcript:C41D11.1f.2 I WormBase five_prime_UTR 675 861 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 675 861 . + . Parent=transcript:C41D11.1f.2 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 675 861 . + 1 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 862 917 . + . Parent=transcript:C41D11.1a.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1a.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 862 917 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN873600 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1a.2 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 918 1056 . + . Parent=transcript:C41D11.1f.2 I WormBase five_prime_UTR 918 1056 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 918 1056 . + . Parent=transcript:C41D11.1f.2 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 918 1056 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1a.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1a.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1057 1106 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1a.2 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 1107 1213 . + . Parent=transcript:C41D11.1f.2 I WormBase five_prime_UTR 1107 1213 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 1107 1213 . + . Parent=transcript:C41D11.1f.2 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 1107 1213 . + 2 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1a.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1a.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1214 1258 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN880833 %3B Confirmed_cDNA FJ009009 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST OSTR079A7_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1b.1 I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 1259 1374 . + . Parent=transcript:C41D11.1f.2 I WormBase five_prime_UTR 1259 1374 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 1259 1374 . + . Parent=transcript:C41D11.1f.2 I WormBase exon 1259 1427 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 1259 1462 . + . Parent=transcript:C41D11.1a.2 I WormBase CDS 1259 1396 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.1;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 1259 1374 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 1259 1374 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 1259 1374 . + 0 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase CDS 1259 1396 . + 0 ID=CDS:C41D11.1a;Parent=transcript:C41D11.1a.2;Name=C41D11.1a;prediction_status=Confirmed;wormpep=CE08658;protein_id=CCD64251.1;locus=eri-6 I WormBase CDS 1259 1374 . + 0 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 1259 1374 . + 0 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase intron 1375 2829 . + . Parent=transcript:C41D11.1b.1;Note=Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST L1_Nanopore_Roach_65206 %3B I WormBase intron 1375 2829 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i2 %3B Confirmed_EST L1_Nanopore_Roach_65206 %3B I WormBase intron 1375 6181 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_cDNA FJ009008 %3B I WormBase intron 1375 8462 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1375 8462 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 1375 11866 . + . Parent=transcript:C41D11.1d.1;Note=Confirmed_cDNA FJ009009 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i3 %3B Confirmed_EST adult_Nanopore_Roach_19601 %3B Confirmed_EST adult_Nanopore_Roach_19601 %3B I WormBase intron 1375 11866 . + . Parent=transcript:C41D11.1d.2;Note=Confirmed_cDNA FJ009009 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g3_i3 %3B Confirmed_EST adult_Nanopore_Roach_19601 %3B Confirmed_EST adult_Nanopore_Roach_19601 %3B I WormBase three_prime_UTR 1397 1427 . + . Parent=transcript:C41D11.1a.1 I WormBase three_prime_UTR 1397 1462 . + . Parent=transcript:C41D11.1a.2 I WormBase intron 1428 11935 . + . Parent=transcript:C41D11.1a.1 I WormBase exon 2830 3084 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 2830 4001 . + . Parent=transcript:C41D11.1b.1 I WormBase CDS 2830 2902 . + 1 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.1;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase CDS 2830 2902 . + 1 ID=CDS:C41D11.1b;Parent=transcript:C41D11.1b.2;Name=C41D11.1b;prediction_status=Confirmed;wormpep=CE43749;protein_id=CCD64261.1;locus=eri-6 I WormBase gene 2871 5429 . - . ID=gene:WBGene00016565;Name=WBGene00016565;interpolated_map_position=-1.28113;sequence_name=C41D11.6;biotype=protein_coding;so_term_name=protein_coding_gene;curie=WB:WBGene00016565;Alias=C41D11.6 I WormBase mRNA 2871 5429 . - . ID=transcript:C41D11.6.1;Parent=gene:WBGene00016565;Name=C41D11.6.1;wormpep=CE08663;biotype=protein_coding I WormBase exon 2871 5429 . - . Parent=transcript:C41D11.6.1 I WormBase CDS 2871 5429 . - 0 ID=CDS:C41D11.6;Parent=transcript:C41D11.6.1;Name=C41D11.6;prediction_status=Confirmed;wormpep=CE08663;protein_id=CCD64255.1 I WormBase three_prime_UTR 2903 3084 . + . Parent=transcript:C41D11.1b.2 I WormBase three_prime_UTR 2903 4001 . + . Parent=transcript:C41D11.1b.1 I WormBase intron 3085 8462 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST L1_Nanopore_Roach_65206 %3B I WormBase exon 6182 6292 . + . Parent=transcript:C41D11.1c.1 I WormBase CDS 6182 6281 . + 1 ID=CDS:C41D11.1c;Parent=transcript:C41D11.1c.1;Name=C41D11.1c;prediction_status=Confirmed;wormpep=CE43808;protein_id=CCD64262.1;locus=eri-6 I WormBase three_prime_UTR 6282 6292 . + . Parent=transcript:C41D11.1c.1 I WormBase intron 6293 8462 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_cDNA FJ009008 %3B I WormBase mRNA 6579 9588 . + . ID=transcript:C41D11.1e.1;Parent=gene:WBGene00016561;Name=C41D11.1e.1;wormpep=CE46891;locus=eri-6;biotype=protein_coding I WormBase exon 6579 6840 . + . Parent=transcript:C41D11.1e.1 I WormBase CDS 6579 6840 . + 0 ID=CDS:C41D11.1e;Parent=transcript:C41D11.1e.1;Name=C41D11.1e;prediction_status=Partially_confirmed;wormpep=CE46891;protein_id=CCD64265.2;locus=eri-6 I WormBase intron 6841 6882 . + . Parent=transcript:C41D11.1e.1;Note=Confirmed_EST OSTF089A10_1 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc10_g1_i1 %3B I WormBase exon 6883 7684 . + . Parent=transcript:C41D11.1e.1 I WormBase CDS 6883 7684 . + 2 ID=CDS:C41D11.1e;Parent=transcript:C41D11.1e.1;Name=C41D11.1e;prediction_status=Partially_confirmed;wormpep=CE46891;protein_id=CCD64265.2;locus=eri-6 I WormBase intron 7685 8462 . + . Parent=transcript:C41D11.1e.1;Note=Confirmed_EST FN886132 %3B Confirmed_EST L2_Nanopore_Roach_78961 %3B I WormBase five_prime_UTR 8463 8546 . + . Parent=transcript:C41D11.1f.1 I WormBase five_prime_UTR 8463 8546 . + . Parent=transcript:C41D11.1f.2 I WormBase exon 8463 8631 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 8463 8631 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 8463 8631 . + . Parent=transcript:C41D11.1e.1 I WormBase exon 8463 8631 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 8463 8631 . + . Parent=transcript:C41D11.1f.2 I WormBase three_prime_UTR 8463 8631 . + . Parent=transcript:C41D11.1b.2 I WormBase three_prime_UTR 8463 8631 . + . Parent=transcript:C41D11.1c.1 I WormBase CDS 8463 8481 . + 1 ID=CDS:C41D11.1e;Parent=transcript:C41D11.1e.1;Name=C41D11.1e;prediction_status=Partially_confirmed;wormpep=CE46891;protein_id=CCD64265.2;locus=eri-6 I WormBase three_prime_UTR 8482 8631 . + . Parent=transcript:C41D11.1e.1 I WormBase CDS 8547 8631 . + 0 ID=CDS:C41D11.1f;Parent=transcript:C41D11.1f.1;Name=C41D11.1f;prediction_status=Confirmed;wormpep=CE43740;protein_id=CCD73359.1;locus=eri-6 I WormBase CDS 8547 8631 . + 0 ID=CDS:C41D11.1f;Parent=transcript:C41D11.1f.2;Name=C41D11.1f;prediction_status=Confirmed;wormpep=CE43740;protein_id=CCD73359.1;locus=eri-6 I WormBase intron 8632 8675 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST FN886132 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8632 8675 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST FN886132 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8632 8675 . + . Parent=transcript:C41D11.1e.1;Note=Confirmed_EST FN886132 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8632 8675 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST FN886132 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8632 8675 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST FN886132 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 8676 8733 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 8676 8733 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 8676 8733 . + . Parent=transcript:C41D11.1e.1 I WormBase exon 8676 8733 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 8676 8733 . + . Parent=transcript:C41D11.1f.2 I WormBase three_prime_UTR 8676 8733 . + . Parent=transcript:C41D11.1b.2 I WormBase three_prime_UTR 8676 8733 . + . Parent=transcript:C41D11.1c.1 I WormBase three_prime_UTR 8676 8733 . + . Parent=transcript:C41D11.1e.1 I WormBase CDS 8676 8733 . + 2 ID=CDS:C41D11.1f;Parent=transcript:C41D11.1f.1;Name=C41D11.1f;prediction_status=Confirmed;wormpep=CE43740;protein_id=CCD73359.1;locus=eri-6 I WormBase CDS 8676 8733 . + 2 ID=CDS:C41D11.1f;Parent=transcript:C41D11.1f.2;Name=C41D11.1f;prediction_status=Confirmed;wormpep=CE43740;protein_id=CCD73359.1;locus=eri-6 I WormBase intron 8734 8939 . + . Parent=transcript:C41D11.1b.2;Note=Confirmed_EST yk1700a02.3 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8734 8939 . + . Parent=transcript:C41D11.1c.1;Note=Confirmed_EST yk1700a02.3 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8734 8939 . + . Parent=transcript:C41D11.1e.1;Note=Confirmed_EST yk1700a02.3 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8734 8939 . + . Parent=transcript:C41D11.1f.1;Note=Confirmed_EST yk1700a02.3 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase intron 8734 8939 . + . Parent=transcript:C41D11.1f.2;Note=Confirmed_EST yk1700a02.3 %3B Confirmed_cDNA FJ009008 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST elegans_PE_SS_GG6499%7Cc7_g1_i2 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B Confirmed_EST young_adult_Nanopore_Roach_99656 %3B I WormBase exon 8940 9441 . + . Parent=transcript:C41D11.1c.1 I WormBase three_prime_UTR 8940 9441 . + . Parent=transcript:C41D11.1c.1 I WormBase exon 8940 9465 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 8940 9465 . + . Parent=transcript:C41D11.1e.1 I WormBase exon 8940 9465 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 8940 9465 . + . Parent=transcript:C41D11.1f.2 I WormBase three_prime_UTR 8940 9465 . + . Parent=transcript:C41D11.1b.2 I WormBase three_prime_UTR 8940 9465 . + . Parent=transcript:C41D11.1e.1 I WormBase CDS 8940 9372 . + 1 ID=CDS:C41D11.1f;Parent=transcript:C41D11.1f.1;Name=C41D11.1f;prediction_status=Confirmed;wormpep=CE43740;protein_id=CCD73359.1;locus=eri-6 I WormBase CDS 8940 9372 . + 1 ID=CDS:C41D11.1f;Parent=transcript:C41D11.1f.2;Name=C41D11.1f;prediction_status=Confirmed;wormpep=CE43740;protein_id=CCD73359.1;locus=eri-6 I WormBase three_prime_UTR 9373 9465 . + . Parent=transcript:C41D11.1f.1 I WormBase three_prime_UTR 9373 9465 . + . Parent=transcript:C41D11.1f.2 I WormBase intron 9466 9553 . + . Parent=transcript:C41D11.1b.2 I WormBase intron 9466 9553 . + . Parent=transcript:C41D11.1e.1 I WormBase intron 9466 9553 . + . Parent=transcript:C41D11.1f.1 I WormBase intron 9466 9553 . + . Parent=transcript:C41D11.1f.2 I WormBase exon 9554 9588 . + . Parent=transcript:C41D11.1e.1 I WormBase three_prime_UTR 9554 9588 . + . Parent=transcript:C41D11.1e.1 I WormBase exon 9554 9611 . + . Parent=transcript:C41D11.1b.2 I WormBase three_prime_UTR 9554 9611 . + . Parent=transcript:C41D11.1b.2 I WormBase exon 9554 9646 . + . Parent=transcript:C41D11.1f.1 I WormBase exon 9554 9646 . + . Parent=transcript:C41D11.1f.2 I WormBase three_prime_UTR 9554 9646 . + . Parent=transcript:C41D11.1f.1 I WormBase three_prime_UTR 9554 9646 . + . Parent=transcript:C41D11.1f.2 I WormBase gene 10071 10409 . - . ID=gene:WBGene00219721;Name=WBGene00219721;locus=linc-104;sequence_name=T01A4.7;biotype=lincRNA;so_term_name=lincRNA_gene;curie=WB:WBGene00219721;Alias=linc-104,T01A4.7 I WormBase lincRNA 10071 10409 . - . ID=transcript:T01A4.7;Parent=gene:WBGene00219721;Name=T01A4.7;locus=linc-104;biotype=lincRNA I WormBase exon 10071 10326 . - . Parent=transcript:T01A4.7 I WormBase exon 10379 10409 . - . Parent=transcript:T01A4.7 I WormBase gene 10488 12189 . + . ID=gene:WBGene00271778;Name=WBGene00271778;interpolated_map_position=-1.27704;sequence_name=T01A4.9;biotype=protein_coding;so_term_name=protein_coding_gene;curie=WB:WBGene00271778;Alias=T01A4.9 I WormBase mRNA 10488 12189 . + . ID=transcript:T01A4.9.2;Parent=gene:WBGene00271778;Name=T01A4.9.2;wormpep=CE52109;biotype=protein_coding I WormBase mRNA 10488 12183 . + . ID=transcript:T01A4.9.1;Parent=gene:WBGene00271778;Name=T01A4.9.1;wormpep=CE52109;biotype=protein_coding I WormBase exon 10488 10924 . + . Parent=transcript:T01A4.9.1 I WormBase five_prime_UTR 10488 10843 . + . Parent=transcript:T01A4.9.1 I WormBase exon 10488 10924 . + . Parent=transcript:T01A4.9.2 I WormBase five_prime_UTR 10488 10843 . + . Parent=transcript:T01A4.9.2 I WormBase CDS 10844 10924 . + 0 ID=CDS:T01A4.9;Parent=transcript:T01A4.9.1;Name=T01A4.9;prediction_status=Confirmed;wormpep=CE52109;protein_id=SOF58721.1 I WormBase CDS 10844 10924 . + 0 ID=CDS:T01A4.9;Parent=transcript:T01A4.9.2;Name=T01A4.9;prediction_status=Confirmed;wormpep=CE52109;protein_id=SOF58721.1 I WormBase intron 10925 11866 . + . Parent=transcript:T01A4.9.1;Note=Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g6_i1 %3B Confirmed_EST L1_Nanopore_Roach_25664 %3B I WormBase intron 10925 11866 . + . Parent=transcript:T01A4.9.2;Note=Confirmed_EST elegans_PE_SS_GG6499%7Cc6_g6_i1 %3B Confirmed_EST L1_Nanopore_Roach_25664 %3B I WormBase exon 11867 12183 . + . Parent=transcript:C41D11.1d.1 I WormBase exon 11867 12183 . + . Parent=transcript:T01A4.9.1 I WormBase exon 11867 12186 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 11867 12189 . + . Parent=transcript:T01A4.9.2 I WormBase CDS 11867 11918 . + 1 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.1;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 11867 12061 . + 0 ID=CDS:T01A4.9;Parent=transcript:T01A4.9.1;Name=T01A4.9;prediction_status=Confirmed;wormpep=CE52109;protein_id=SOF58721.1 I WormBase CDS 11867 11918 . + 1 ID=CDS:C41D11.1d;Parent=transcript:C41D11.1d.2;Name=C41D11.1d;prediction_status=Confirmed;wormpep=CE43795;protein_id=CCD64264.1;locus=eri-6 I WormBase CDS 11867 12061 . + 0 ID=CDS:T01A4.9;Parent=transcript:T01A4.9.2;Name=T01A4.9;prediction_status=Confirmed;wormpep=CE52109;protein_id=SOF58721.1 I WormBase three_prime_UTR 11919 12183 . + . Parent=transcript:C41D11.1d.1 I WormBase three_prime_UTR 11919 12186 . + . Parent=transcript:C41D11.1d.2 I WormBase exon 11936 12186 . + . Parent=transcript:C41D11.1a.1 I WormBase three_prime_UTR 11936 12186 . + . Parent=transcript:C41D11.1a.1 I WormBase three_prime_UTR 12062 12183 . + . Parent=transcript:T01A4.9.1 I WormBase three_prime_UTR 12062 12189 . + . Parent=transcript:T01A4.9.2 bcftools-1.21/test/csq/ENST00000000000/upstream-stop.cmd000066400000000000000000000002571467060157400221340ustar00rootroot00000000000000{bin}/bcftools csq -p a -f ENST00000000000.fa -g ENST00000000000.gff upstream-stop.vcf | {bin}/bcftools query -f'[%POS\t%REF\t%ALT\t%SAMPLE\t%GT\t%TBCSQ\n]' | ../sort-csq -q bcftools-1.21/test/csq/ENST00000000000/upstream-stop.cmd.out000066400000000000000000000010161467060157400227340ustar00rootroot000000000000006723 A T aaa 1/1 stop_gained|WBGene00016561|C41D11.1e.1|protein_coding|+|49K>49*|6723A>T+6725G>A stop_gained|WBGene00016561|C41D11.1e.1|protein_coding|+|49K>49*|6723A>T+6725G>A 6725 G A aaa 1/1 @6723 @6723 7395 G T aaa 1/1 *missense|WBGene00016561|C41D11.1e.1|protein_coding|+|259D>259Y|7395G>T *missense|WBGene00016561|C41D11.1e.1|protein_coding|+|259D>259Y|7395G>T 7395 G T bbb 1/1 missense|WBGene00016561|C41D11.1e.1|protein_coding|+|259D>259Y|7395G>T missense|WBGene00016561|C41D11.1e.1|protein_coding|+|259D>259Y|7395G>T bcftools-1.21/test/csq/ENST00000000000/upstream-stop.vcf000066400000000000000000000004131467060157400221410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT aaa bbb I 6723 . A T . PASS . GT 1/1 0/0 I 6725 . G A . PASS . GT 1/1 0/0 I 7395 . G T . PASS . GT 1/1 1/1 bcftools-1.21/test/csq/ENST00000218032/000077500000000000000000000000001467060157400166405ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000218032/ENST00000218032.fa000066400000000000000000000407721467060157400207730ustar00rootroot00000000000000>X X:12924719-12941308 GCCATTTCAGGAAGTTAGCCAGTTTCTCTTCTCGGCCACCTCCTGCATAGAGGGTACCAT TCTGCGCTGCTGCAAGTTACGGAATGAAAAATTAGAACAACAGAAACATGGTAAGCCACT TCTATTTCTTTAGCAAAGCTTTCCAACAGAATATGGGGTTTCTGACCCAGAAATCTGGGT TGGTGGCAAATGGTGTGAGCCTAGAAAGTAATAAATGGGCAAATAAGGATAAAAATTAAA GATCGAAACAACTGTAAATGCAGGTAAAGCGGCTTGCTATGATCTTTAATTTGTGCACAC GTTAGTATAAAGGAATTAGAGAGTAAATTTTGAAAATCAAATGCAGTGATGATCTTACTA ATTTGGACAGGAAAATAAGAAAATTTCAAGTTAGAAATTGAACTGGAAATATTACTTACT GGCCCTACCAGAGACAATATCCTCTTCCAGAACAACAGGGTTGGAAGAGAAGGTGAGGGA AATATTCTTCCTTTGCTATTTCTGTAGAAAAGGACAAACTCTCTTCCTTCACATACATAG GTCAATTGCTAGATCCTAGTGAAGCCTGAGCTTAACCTACTGTTGGAGGCTTAAAGTTCG ACATTAATTGCTACTTTTCTTGGTCAGAGTTTTAAATAATTAGGTTGGTACAAAAAACTG TGATTACTTTTCCACCAACCTAATAACATGCTACAATTTCTGTAATTATTATTTTACACT GTCAAGACATAGCAGGTGGTCCGTTTTTGTTATTGTCAAGAACTGTCAGACTAAAAATGA ACTTTACACTTCTTTTTAAATGATACATTTTCTAGAAAATTCAATGAGGTTTAAGAGCAA TTGAAAAGTCTGATTTCAAGAGAGTCTCATCCAAAATGTACTATATATTTTTCCCCAAAG TCCTTGGAGTTAATTTTGACAACAATTTAAAGTACACTTAAGTCTTTTGAAGTTAATGGG TCTGCCACCCAGGTTGGAGTGCAGTGGCGTGATCTCAGCTCACTGCAACCTCCGCCTCCC GGGTTCAAGCGATTCTCCTGCCTCAACCTCCCAAGTAGCTGGGACTACAGGTGTGTGCCA CCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGCCAGGC TGGTCTCGAACTCCTGACCTCAGGTGATCCGCCTGTCTCAGCCTCCCAAAGTGCTGGGAT TACAGGCATGAGCCACCGCGCCCGGCCTGAAGTTAATTTTTATACCCACCTAATGTTCAT TATGGATCTTGAAGGTAAATTAATTCTGCACTAAAATTTTACAATGCTTTACAAAATGAC TGTAGGTGGCCCATATGGAATTCGGTCAACTGGGCCAATGACACATATGGGATTGCAGTT GAAATTATCCAATTCCTACTTGATATTTGTAAGCTGCTGTGATAGCCAGTATAATTGTAC TGTAAGAATGTGGTAAATAGCCGGGGCCCGGTGGCTCACGCCTATAATCCCAGCACTTTG GGAAGCCGACGTGGGCGGATCACTTGAGGTCAGTAGGTAGAGACCAGCCCGGTCAACACG GCAAAACCTCGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGTACGCACCTGT AGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAGCCCATGAGGTGGATGTT GCAGTGAGCAAAGATCGCACCATTGTACTCCAGCCTGGGCAACGGAGTAAGACTCTGTTT CAAAACAACAACAACAACAACAACAACAGATTGGTAAATAGAGTAATAATAAAATCAAAT TAAACTTGCAAAAAATGGCCACTTTGCTCCCACTGGTGGCCAATGGAGGTCAAGGACCTG GCTGACCTCCTGCCTAAAGGCAGAGGTTGTTAGCCTTCGCAATGGACTCAAATCAGAGGG GGAGCTTTCAAAACTCCTGCTGCCCAGACTGAACCCCAGATCAATGAAACCAAAATCTCT GGATACAGGGCTTGGCATTTGTAGCTTTTAGAGTTCCTAAGTATCTCTACTGTGCAGCCA AAGTTAAGAATCAGTGCCTTAGAACATCAACAGTTTTTTGGTCCTTTTGTTAAAAAGCAC AGTCCGTTTTTTTAGGTGGCTAGAAATGCTCCAGGAAGAGCTGAAATGTATTTACCAGCC ACCTTGGTTTGATTTTAGAAAGCAAAATAGAAGTTCTAAGTATGCTTTCTCTGAAAAGCT GAGACTGCAGATAAGAGTGAGGGCAGTTGATGGAGTTCATTCTCCTCTTTCAATCACTGC TTCTCATCCTTTCATTATAATAATCTAAGAATCTCAGAGATTATGAAAGAGAAAGCAGTC TTATGGAAGACCCCAGACTCACAGAATATTAGGGTGTGTTTCACAGGGAAGGATGTCATT ACCCACAGTTAGTCTTTGAAACGCAGTTGGACATTATTTGTAAGTGCATCATAGTGTCGC CTCCAGGTTCCATTGAGGGGAACGTCATTCCAATGCAACATCTCTGAGTTCATCTGGGTT ATTAAATGGGGTTGAGGGATTTGTTATTTTTAAATTAGTAGCCCCAATTTAGGACTACTC AAGACCATAGGACAAGCCTGTCCAACCCTCGGCCTGCGGGCTGCATATGGCCGAGGACAG CTTTGAATGCAGCCCAAGACAAATTCATAAACTTTCTGAAAATATTATGCATTTGTTTTT TAGCCCATCAGCTACTGTTAGTGTTAGTGTATTTTATGTGTGGCCCAAGACAATTCTTCT TCTTCCAGTGTGGCCCAGAGAAGCTGAAAGATTGGACACCCCTGCTATAAGACACAGTAA TATAAATACATAACCTGTGGTTCTGGATTGGCATTAGCAGATACAGGCTGTGTTGATTTT GCAGAAAGTTACAAAGAGCTGCTAGTTGGTGTGTATGTCTAAAATCAGTAGATTTCCTGT GGTTCTAAGGAATGACAAAGAATCTGGAAGTTCTCTGTGGTAGCCTGCTCAGTGCAGAAA GGGAACGTGGAAAATCCGCCACCAGCATTTGAGTCTTGGAGGTTCCACATAGGGCTATCA GGTCTCTGCTGATCACTGAAACCAGATCATGGCCAACTAGCCCCTTGGCTTCAGCCCTCC CAATTCATTAACTACTCAGGTAAATCTAGGGTCACTTTCAACTCTACCACCTACCATCTG AGTGACCTTGAAAACATTCATCTCTCTGAGCCTCAGGTCCCATGTCTGTAAAGCAGGGGC CTCATGGACTTCTTTGGGTTTTTTTGTTTTTGTTTTTGTTTCTGAGGATTAAACAAATGC TCCCTACCCTATTTCCCAGCATCCAGTAACACAGTTTTTCATATTTTTGTGTATGTTAAG TCAGGACCCATCTCTTTAATGATAAGTGCACTTAATGTGGTCATGTTTTCTTTTGTCTTC CAAAGCTGTTAGTGAATCCATTGAATTTGGGATGGGTAAAATAAAGTATCTATTATTAAT TGTAAATTTCATCTAAAGTGACAAATCCTACCTGCATAACCATTTCTTAATTTCCTTTCA TCATGTATCAGTGGTCAACATTGTTAACTGCGAATGAATCAGAATCCATCAAAAATTAGA ACTATTTCCAGTCTGGCAAAAATTCAGCTCTGGTTGAATCCAAACATTGTGCTGAAGCAG CTAAGTAATTCAACTGAGGAGATTAATTACATGTTATAATCAATAGGTTCTCTTGACACT TCAGTGTTAGGGAACATCAGCAAGACCCATCCCAGGAGACCTTGAAGGAAGCCTTTGAAA GGGAGAATGAAGGAGTCATCTTTGCAAAATAGCTCCTGCAGCCTGGGAAAGGAGACTAAA AAGGTAAAAAGCTGTTAATTCCAGGAAGACAGCTTTACGCCCCTCCCAGACCACCTGCAC TGCACACTACGTGGAATTTATTTTAGTCTCACATGGCAGCGTCCCTACCTTTGTGCCCAC ACATCTGGTCTCCGCCCTGGCTGCAGCCCTCCCCTTCAGGCGAATTCTGGGTGTGTCCTA TCTGCTCATTGCAACTCCCAGCGAATGAGTTTTCAGCGAAGGCAGACTTTCTGACCTGTT CTTCAAACTGCACTGGTCTTTTAAAAACGTGTTTGGTGGCCATCAGCATCCAATTTCAGA AGAAAGATTTGGGTGAGGACTGAGAGAGGCTGTTGTTGTTGTGCTGTCTGTTTCCTTCAG AATCTGCAGAAGAAAATTGGCAGGTCATGTACTGTGGACCTAACCAAAGGACAAATGATG TATGGAAAATAGAAAAACTGTTGTGAAATTGCTTCCTCATTAGCAATAACTGTATTTGGC AGGGAGAGGAGAAGTTGGGCACATTTTTTTTTCTTTTTTTTTTCATGATTCATACGTTTT CTTTAAAGAAGTGGGTTTTGCTTTTCACTGGGTGCTCTAAGACAACCCCAGTGAAAGATC TGGACCACGAAGACCCAGTCATCCTCATAAGGGTGTTCATTGCAGCAAGCTCAAGGGCAT GCCAGGCAAAGGCCTTTTTTCTGGCAGCTTGAACTTGTCTCAGCAGAGGGTTTCACAGAA CAACTGTCATTTACCTGTTCTCTGCTCTTACTTGATTCGTTTCCCAGGACTGCTGAAACA AAGTACCACAAACTTGGTGGATCAAAACAGCAGAAATATATCCTCTCACAGTTCTGGAAA CCACAAGTCAGAAACCAATGTGTTGTTGGCAGGGTTGGTTCCTTCTTAAGGGGCTAGAGG GAAAATCTGTTTCATGCTCCTCTCCCAGCTTCTGGTGGTAGCTAGCAATTCTTGATGCTC TCTGGCTTGCCGCTGCATCTCTCTAGCCTTCACCTCTCCTCATGTGGGTGGCCTTCTTTC CTGTGTGTCTATTTCCAAATTCCCCTTTTCTTATAAGGGGACCAGTTATTGGATCAGGGC CCACCTTAATTCAGTAGATCCCATTTTAACTTGATGACATCAGCAAAGTCCAAATAAGGT TGTATTCACAGGTACCAGGGGTTAGAACTTCAAGTTATCTATTAGGGGACACAATTCAAC CTAAAAACTCCCCTTTTTTGATTCTCTATTCTGCCACTTCTACTCAATCCAGGTTCTTCA CTTCATCAGCTCCCAATCTAATACTTATCTTATTTCTAGTAAGCATCTCTTCCTTATCTT AACTGGTCCCTGGGGCCTGGCCCGAGCCCCATTATACCATCAGCTGTTGACATCAAGGGT GGACTTCTCTTTCGGCACAGAAGGCACAGGGCTGTAGGCTTCAGCCTTCTCTGCTTTGCT CTGCCCCATCTACTGTTCATCCACCTGCTTTCCATTTTGCTAAACTTTGTAGAAAATTCT TGTCAGCTGTTGTCTCCTCCTACACTTTCTTTGATCTTAGAGGATTCTATTCTTTTACTA TGGCTTTAATCGGAGCACCCGACTGTTAGGTTCAACCAACAGAAGTTGGTTGTGCTCTCT CACTCTTTCTTTCTCTCTCTCTCTCTTTCTCTCTATTTGCATAGTGGTATTTTTTTTTTC CTCTATTTTATTGGCAGAATTGCCATTTCTCTAAGTTATTGTAGAGTTGCTGTTTCTCTA TTTTATTTGCATATTTCTCTTCTGCCAGGCTGGATTGTTTCTATTGATTGGTTCTGCTGT AATGAGGGTGACTTCTCATTAGTATCCTTCTCACTTCATCTGGGACCAGATGCCCTTTGA TATCCTTTTGGAGCCACAACTTTTGGTAGTCAGAGGCATGGGTGTGGCTCAAAGGAAGAA CTTGGCTCAGAAGGTGCAGCTCTTGCTGGGCCTTTGGTCTCTGCTCTGTCTTCTGAGATC AGTGGCTGCTGGGACCTGGGGTTCCCCCATGCCGGGCATGGTCACACAGCACTCCTATGG ACTTGAGCAGAGCACCCTGCAAAGTGAGCATTAGCAATCCATTCCAACTCTGTGCAGTCC TGCACGGAATATAGAAGGTGGAGCAATGACAGTCTCCCCAACTTCTCTGCAAGCAACCTG CTCACCATTTCTTGCCCTTCCCATTTATGTACTTTTCAAAATCAGGTTATTTGGAATTTG TCGACTCATGTTTCTTACTTCAGTACTTTTTTGGGAGGGCAGCATTAGAAACCTCAAACT CTTAACTAAAAAATGTCTTTGGGAATGTTCTGGCCATTTTCATGGCCCACAATTTGCTTT AAGCTGCTTTAGACTCTCCCAGAGGCTATTTTCATCCCGAAAGAACAGAGCAGAGCTCAA AAGACTCCAGTTTTGGTCTCTAGCAGCCCCTAGAGGATTTCCCCCTCAATTCCTCTCTGC CTTGTATGAAATAGAATTGGATTTGAAATCGGATGTTGAGGCCTTACCTCCAGGCTAGTG AGGCCACACAAGATGGATCCTCTGGACCCGCCCAAGTGTCCACCTAAACATGAGTTACCA ACTAACAATGTTTTGTTTAGCATGCAAAGGGAGTGGTCTGGAATCTGGCCTTGCCCTGAC ATATTCTCCTTGGGCCTTTTTAAAAAAATAATTTGTGTTAATCTGTAGTTAAAAATTATA ATAAGGACCTGACAAACACTACCTCAGTCAGATGATCAAGGTACACATAAATAGTGAAAG TCATGTTGATAGCATGCACCCTTCATATGATATGGCTAGAATGGCCCTGCACTTCTGTGA TCTTCCTCCCCTAGACTCATCAGCTCGATCTAATCATAACAAAAGCATCAGATAAGTCCC CGCCCAGGGACATTCTACATAACCATTTCCCTTCCCAGTTATATTTTTCTCCACAATACT TTCCACCATCTAACATTCTATCTTTCAAAATGGGCAAGTATTTTAGCCTGGTTTGTTCAT TGTTTTATCTGCAACTCAAATACAGTTCCTGAAATAAAATATCTGCCTAATAAATATTTA ATGAATGAATGAATATAGCATTGCCTTATCCGTTTAATTGCCACATGGTATTTCATTGTG TGAACATAATATCGTTTATTTACCCAGACTACTACTCATAGGCATTTAGATTATTTCCGG TCTTTTGCTATTGCTAACAGCCTTTGCAATGAACATCCTTGTATACAGACATTTGCATAT ATGAGGGTGTGTCTTTAGGATCTACTTCTAGAATTGAAATTGCCAACTCCAAGTATATGT TTCCAATTGTGATAGATATTACACATTACCCTCCATCTTAGAGGTGGTGTTAATTTAGAT TCCTGCCAGCAAAATTTAAGAGTGTTTGTTTCCCCATATCCTCAACTGCCTAACAGAATC AGTGAAAAATGGTATGACAGTGTAATTTTTGAGTGAGGTTGAGTATCTTTTCCTATGCTT TAAGAGCAATTTATGTTTCCTTTTTATGTGAACTGTCTGTTAATATATTTTTTCAATTTT TCTATTGGGTTATTTGTCTTTTCATTAATGCATATACCTGTTACATATTTATACCAAGTA TGTATTAAATACTAACATATTGATGAAACAGAGCAAAAAGCCTAGAAATAGATCCAAATA ACAGAAGAGTTAGTATGTGATACAGGAAGCCTATAAAATCAGTGAGCAAAAGACCATCCA ATTAATAACGTTAGGGTAAATGGGTCTCCATTTAGAAAAAAATAATGTGGGTCTACACCT CACATTTTATACCTAAACAATTCCAGTGGGATAAGAAAATGAAATCATAAAAAATTACTA GGAAAAAGATGAGAAAATTGTTCATAAAACTGAAGTGTGGAAGATCCTTTATGCCTTACA CTGCCCTGAGTGATCTCATTCATACCCATGGCTTCAATTGTCATGAATCCCAAATTCATT CCTCTGTCAGAACTCTCTTCTGAGCTTCAGACCCACATACTCAGCTGCCTACTGGACACC TCTACTTGAATATCACAAACTCAACTCAAAAGCAAACCTGTCAAATTTAATTACTAGTAG CCCTACCCCAAACAATCTTCCTGCTCAGTGAATGACACCCATCCCTCCAGGTGCACAGAC CAGGAACCTAGAAGTCACTCTGATTGCATCCCTCTCCCTCACAACCTCTACCTCCCTTTA TTCATCCATTGCTATGTCTCTCAAATGTACCTCCCAAATATCTCTTGAACGCGTTCTTTT CTATCTCTATTGCCACCACCCTAGTTCAAACTCCCATCATCTCATGACTGAAGTTCTGTG CCCTCTTGCCAGTGAACACTGTAGAATCAATCTAAACATGGTGCCACCCTGCTTAAAAAC CTTCAAAGGCTCACATCACTTCTCAGATGAAGAGATTGGGGAGACGTTGGTAATAGGACA CAAAATTTCAGTTAGGCAGGAGGAAAAAGTTCTATTGAAGAACTCTATTGTACAATATGG TGACTATAGTTAATAACAACATATTATACACTTGAAAATCACTAAGAGAGTCCATTTTAA GTGTTCTCATGACCAAAAAATGATAAGTATATGAGGTAATGCATATGTGAATTAGCTTGA CTGAGGCATTCTACATGTATACATATTTCGAAACATCATGTTGTACATCATAAATGCATA CACTTTTTAGTTGTCAATTTAATTAATATTTTTTAAACCTACTCTGGCCTTTTTTTCCTT TTTTGAGACGGGTGGTCTCTGTCCCCCATGCTAGAGTGCAGTGCGCAATCATGGCTCACT GCAGCCTCCACCTCCCAGTCTCAGGCGATTCTCCAGTCTCAGCCTCCCAAGTAGCTGGGA CCACAAGCATGAGCCACCATGCCCCGCTATTTGTTTTTGTATTTTTTGTAGAGATGGGAT CTCGCCACATGGCCCAGTCTGGTGTCCAACTCCTGAGCTCCAGTGATCCACCTGCCTCAG CTTCCCAAACTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGTCCACTCTGGTCTTTA CTCAAGTCCCTGGCTTTCTCTCAGTCTCTTAAACTTATGTGCTTAGTAAGATGAGGACTG AAAAATGTCCACAGAACATAGTGACATGGAGATACTGAGAACCTCAACGACATCTCCATT AGCCACTTCCTCTGTGCCATTCCAGTCCTCTGGGCCCCACTGTGGCAAGCAGTCCTACCA TGGCAAACATGAAAGCTGATGTGCCTTGTCTTAGACCCACACCATATCTCTCTGAATTCC TGTCCCAGGGCTTCTCTGGAGGTACAGCCTGGGAAACTCACGGGAATAGACACAGGGCCT TTGCACATGCTGCTCCCTTTTCCTGAAAAATTCCTTTGACATCTTGGTTGTGCCTTACAC ATGCCTACTCAACCTTAGGATTGCAGTTCAGGTTTCACTCCTTTTTTTTTTTTCTTTTTG AGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGTGTGATCCTGGCTCACCA CAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAACCTCCTGAGTAGCTGGGAT TATAGTCATGCACCACCACGCCCAGCTAATTTTGTATTTTTAGTAGAGACAGTGTTTCTC TATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCGGCCCGCCTCGGCCTAG GTTCCACTTCTTTATGGAAATCTTCCCCAGTTGCCTTGACTAGGCCAAAGTCCCCTCTTC TTAGGCTCTTACAGTGTCATGCACTTCTTTTTTATCACAGTGTAAACCTTGTAATGTTGT GTTTAAGTCATATCTGTTGTACCCATGAGACTGGGAGCCAATTCATATATTGTGAGTGTA ATCGAACAGACTTCCCAGGCCACCCACTAGCTAATCAAGGCAGGGATGAGTCCGGAAAGT GACTTTGAAATCTAGCAATGTTGGAACTTGGAAATCACACAGGCTGAGATCTGCTCAGGT GCCTGAACAAATATAGCATTGCCTGTGGCGTCTCCCTCAAAGTGCCTTGCATGTCTGAGC CCCGTTGCCCCTTCCTTTGGTGTGCCTGTGTCTCCCGGTACAGATGTGAAGCCTGGAGAC CTGTGGCTGCCTCTGCAGGAGCTCCATGTTTTCAAGCCATAAATCATCTTAGAATTCATA GCATCTAGATATATTAGTTTTCTATTACTGCAGAACAAATCGCTCCCAAATGTAGAGGCT TCAAAGAATGCCCATTGATTGGCCTTAATTTCTGTAAGTTAGAATCTGGGCAGGTTTGCC TGAGTTCTCCACTCCAAGTCTCATAAAGCCAAGCTGGGCTGTCATCTGGAGGCTCTGAGT AAAAATTTGTTTCCAGGTTCATCCAGATTGTCAGGTGATTTCAGTTCCTTGCAGTTGTTG TTCGACTCACTACCCCACCACCACCCCGAAAACCTCATTTCCTTGCTAGCTGCCTGCAGA GAGCCACTCTCAGCTTCCACAGGCTGCTTGCATTCCTTGTTGTGGGGCCGCTACCTCCTC AAGCCAGAAATAGGGCATCCAGTTCTTCTCATGCATCCTACCCCTCTGACTTTTCCTTCT GCCGATAACCAGAAAAAACGTTCCGCCTTCAAACGCTCGTATGATTAGACTAAGCCCATC CAGATAAATTCCCATATGCCATATACTATAATGTCATCACAGCAGTAATACCCGGGACAA AATTCATGGGGGTCATCTTAAAATTCTGCCTATCACACCAGGTATAGTAGAGGCTTGTTT TAGTGCAAGTTAAACATTAAGCAGCAACATCACGATAGTGCTGCATTTGAAAATAACTAC TAGCAACTGAACATGTCTGGGAGTTCTGCTCCACTTTAATTTCCATCTCAAAAGGAGCTG GGTTTTCCTTGGCTGTTACAAATGGGCAATAATGATTGAGCTTAAGAATAATCAATGTCC ACATAAAAATCTTTTATAACATAGTGAGAGTGTGACATATAAAGGTGTTAGTTCACCGGC CCTAAATTTTAGGAGAATTTTTAAAAAGGCACTTATCTGGTTTAATCCATAATAAAGACA TGAGTTGGGCTTTAGTGAAAAATCTAGGCTGGTTTCTGTGTTCAGTGAAAGAAGATTTGA GAGTTCTCTTAATTACAACCCTTGATCAAACCTACCACATTAATCTGTTTATTGCATTGT ATGGTTACCAAAAGTGATATATTCAGCCCTCTATTTATTAAGAAACAGTTACAGAAAGTG AGGCACTCTCCTGTGTTACTGAGGGTGCATAAAAATATAAAGCACCATGTGTCTTCCCTA GAGAAGTTTCAAAACTAGCAAGCAAATAGCTATTAATGCTAATGTTTGTGTGATAGGGAA CATATGAGTAGTAATTATTCCACAAACAATTTTTTGAGTGCTGTTTACATTTGAGGCACA GTTCAGGCACGAGGATTTCAAAAGGAGATTGTGTAGCATGATGGCTTGTTAAAAATATGA TTTTGGAATCAGATTTGCTCAAGTCCCAGTGCTACAGCATACCATCCTTCAAAAAGGTAC TTAAGTCTCTGAGTTTGTTTTCTCATCTGCAAAATATAAATAATAAGAGGACCTACTGCG TCATGTTCTTGTGAGCATTAATGTGGGTGATGAAATGTTTATGAAGCACTTAGCACAATA CCTGACATTTTGTTTGTTATTATTATCAACATAAAGTGCCCACTTTCCAGTCATGCAAGA AGAAAACATAATATATGTCACCATAGAAGTATAGAACAATTGTGGGAAATACCAGTAAGA GAGATATAGCTGTATAAATAAGGTAAAGATGACTGCCTAGAAGATCTAGGATGATACCAT ATTAGAAGTTGCATCTGAACTCTCCTTGGGGACTGGCCAAAGTTTCATCAAGTGTCATGT CAGTAGGTTGGTGCTATAAATATATAGCTTGCAAAGCTATAGACTTACTATAAACCATAG CTGTGGTCCAGCTTAGACTCATTATGGTGGTGGAGTATCTTGATTAATGGCCTCTGCAGA AGCTTCCCAGGTCTTCTCATCATCATAATCTCAGATAGCTTCATCTTCAACTTCCTTTTT TTTGTTGTTTTTGAGACAGGGTCTCACTCTGTCATCCAGGATGGAGTGCAGTGGCACAAT CATGGCTCACTGCAGCCTCGACCTCAGGAGCTCAAGCCATCCTCCCACTTCAGCCTCCCG AGTAGTTGGGACTACAGGCATGCACCACTACGCCCGGCTAATTTTTTCATTTTTTTGTAG AGTCAGGGTCTCCCTATGCTGCCCAGTCTGGTCTCAAACTCCTGGGCTCAAACCATCTTT CCACCTCGGCCTCCCAAAATGTTGGGATTACAGGTGTGAGCCACCACACACAGCCCATCT TCAACTTCTTTTAGCACCATGAAGCTGAACATAGTAAAAAAGTAAAATCATTCTGGACCT AATCTGATGCAATTTATTTAATTGTTAAGTGAATGCACACATCAAAATTCATACAAGTAT GGGGCAGCGCTGCTAATTTATTTACAAAACACCTGGCAAATACTGCTACTCTAATACTGT GCTTCCACTTTTGATTTTCCTTAGGAAAACATGTTCCTTCAGTCGTCAATGCTGACCTGC ATTTTCCTGCTAATATCTGGTTCCTGTGAGTTATGCGCCGAAGAAAATTTTTCTAGAAGC TATCCTTGTGATGAGAAAAAGCAAAATGACTCAGTTATTGCAGAGTGCAGCAATCGTCGA CTACAGGAAGTTCCCCAAACGGTGGGCAAATATGTGACAGAACTAGACCTGTCTGATAAT TTCATCACACACATAACGAATGAATCATTTCAAGGGCTGCAAAATCTCACTAAAATAAAT CTAAACCACAACCCCAATGTACAGCACCAGAACGGAAATCCCGGTATACAATCAAATGGC TTGAATATCACAGACGGGGCATTCCTCAACCTAAAAAACCTAAGGGAGTTACTGCTTGAA GACAACCAGTTACCCCAAATACCCTCTGGTTTGCCAGAGTCTTTGACAGAACTTAGTCTA ATTCAAAACAATATATACAACATAACTAAAGAGGGCATTTCAAGACTTATAAACTTGAAA AATCTCTATTTGGCCTGGAACTGCTATTTTAACAAAGTTTGCGAGAAAACTAACATAGAA GATGGAGTATTTGAAACGCTGACAAATTTGGAGTTGCTATCACTATCTTTCAATTCTCTT TCACACGTGCCACCCAAACTGCCAAGCTCCCTACGCAAACTTTTTCTGAGCAACACCCAG ATCAAATACATTAGTGAAGAAGATTTCAAGGGATTGATAAATTTAACATTACTAGATTTA AGCGGGAACTGTCCGAGGTGCTTCAATGCCCCATTTCCATGCGTGCCTTGTGATGGTGGT GCTTCAATTAATATAGATCGTTTTGCTTTTCAAAACTTGACCCAACTTCGATACCTAAAC CTCTCTAGCACTTCCCTCAGGAAGATTAATGCTGCCTGGTTTAAAAATATGCCTCATCTG AAGGTGCTGGATCTTGAATTCAACTATTTAGTGGGAGAAATAGCCTCTGGGGCATTTTTA ACGATGCTGCCCCGCTTAGAAATACTTGACTTGTCTTTTAACTATATAAAGGGGAGTTAT CCACAGCATATTAATATTTCCAGAAACTTCTCTAAACTTTTGTCTCTACGGGCATTGCAT TTAAGAGGTTATGTGTTCCAGGAACTCAGAGAAGATGATTTCCAGCCCCTGATGCAGCTT CCAAACTTATCGACTATCAACTTGGGTATTAATTTTATTAAGCAAATCGATTTCAAACTT TTCCAAAATTTCTCCAATCTGGAAATTATTTACTTGTCAGAAAACAGAATATCACCGTTG GTAAAAGATACCCGGCAGAGTTATGCAAATAGTTCCTCTTTTCAACGTCATATCCGGAAA CGACGCTCAACAGATTTTGAGTTTGACCCACATTCGAACTTTTATCATTTCACCCGTCCT TTAATAAAGCCACAATGTGCTGCTTATGGAAAAGCCTTAGATTTAAGCCTCAACAGTATT TTCTTCATTGGGCCAAACCAATTTGAAAATCTTCCTGACATTGCCTGTTTAAATCTGTCT GCAAATAGCAATGCTCAAGTGTTAAGTGGAACTGAATTTTCAGCCATTCCTCATGTCAAA TATTTGGATTTGACAAACAATAGACTAGACTTTGATAATGCTAGTGCTCTTACTGAATTG TCCGACTTGGAAGTTCTAGATCTCAGCTATAATTCACACTATTTCAGAATAGCAGGCGTA ACACATCATCTAGAATTTATTCAAAATTTCACAAATCTAAAAGTTTTAAACTTGAGCCAC AACAACATTTATACTTTAACAGATAAGTATAACCTGGAAAGCAAGTCCCTGGTAGAATTA GTTTTCAGTGGCAATCGCCTTGACATTTTGTGGAATGATGATGACAACAGGTATATCTCC ATTTTCAAAGGTCTCAAGAATCTGACACGTCTGGATTTATCCCTTAATAGGCTGAAGCAC ATCCCAAATGAAGCATTCCTTAATTTGCCAGCGAGTCTCACTGAACTACATATAAATGAT AATATGTTAAAGTTTTTTAACTGGACATTACTCCAGCAGTTTCCTCGTCTCGAGTTGCTT GACTTACGTGGAAACAAACTACTCTTTTTAACTGATAGCCTATCTGACTTTACATCTTCC CTTCGGACACTGCTGCTGAGTCATAACAGGATTTCCCACCTACCCTCTGGCTTTCTTTCT GAAGTCAGTAGTCTGAAGCACCTCGATTTAAGTTCCAATCTGCTAAAAACAATCAACAAA TCCGCACTTGAAACTAAGACCACCACCAAATTATCTATGTTGGAACTACACGGAAACCCC TTTGAATGCACCTGTGACATTGGAGATTTCCGAAGATGGATGGATGAACATCTGAATGTC AAAATTCCCAGACTGGTAGATGTCATTTGTGCCAGTCCTGGGGATCAAAGAGGGAAGAGT ATTGTGAGTCTGGAGCTAACAACTTGTGTTTCAGATGTCACTGCAGTGATATTATTTTTC TTCACGTTCTTTATCACCACCATGGTTATGTTGGCTGCCCTGGCTCACCATTTGTTTTAC TGGGATGTTTGGTTTATATATAATGTGTGTTTAGCTAAGGTAAAAGGCTACAGGTCTCTT TCCACATCCCAAACTTTCTATGATGCTTACATTTCTTATGACACCAAAGATGCCTCTGTT ACTGACTGGGTGATAAATGAGCTGCGCTACCACCTTGAAGAGAGCCGAGACAAAAACGTT CTCCTTTGTCTAGAGGAGAGGGATTGGGATCCGGGATTGGCCATCATCGACAACCTCATG CAGAGCATCAACCAAAGCAAGAAAACAGTATTTGTTTTAACCAAAAAATATGCAAAAAGC TGGAACTTTAAAACAGCTTTTTACTTGGCTTTGCAGAGGCTAATGGATGAGAACATGGAT GTGATTATATTTATCCTGCTGGAGCCAGTGTTACAGCATTCTCAGTATTTGAGGCTACGG CAGCGGATCTGTAAGAGCTCCATCCTCCAGTGGCCTGACAACCCGAAGGCAGAAGGCTTG TTTTGGCAAACTCTGAGAAATGTGGTCTTGACTGAAAATGATTCACGGTATAACAATATG TATGTCGATTCCATTAAGCAATACTAACTGACGTTAAGTCATGATTTCGCGCCATAATAA AGATGCAAAGGAATGACATTTCTGTATTAGTTATCTATTGCTATGTAACAAATTATCCCA AAACTTAGTGGTTTAAAACAACACATTTGCTGGCCCACAGTTTTTGAGGGTCAGGAGTCC AGGCCCAGCATAACTGGGTCCTCTGCTCAGGGTGTCTCAGAGGCTGCAATGTAGGTGTTC ACCAGAGACATAGGCATCACTGGGGTCACACTCATGTGGTTGTTTTCTGGATTCAATTCC TCCTGGGCTATTGGCCAAAGGCTATACTCATGTAAGCCATGCGAGCCTCTCCCACAAGGC AGCTTGCTTCATCAGAGCTAGCAAAAAAGAGAGGTTGCTAGCAAGATGAAGTCACAATCT TTTGTAATCGAATCAAAAAAGTGATATCTCATCACTTTGGCCATATTCTATTTGTTAGAA GTAAACCACAGGTCCCACCAGCTCCATGGGAGTGACCACCTCAGTCCAGGGAAAACAGCT GAAGACCAAGATGGTGAGCTCTGATTGCTTCAGTTGGTCATCAACTATTTTCCCTTGACT GCTGTCCTGGGATGGCCTGCTATCTTGATGATAGATTGTGAATATCAGGAGGCAGGGATC ACTGTGGACCATCTTAGCAGTTGACCTAACACATCTTCTTTTCAATATCTAAGAACTTTT GCCACTGTGACTAATGGTCCTAATATTAAGCTGTTGTTTATATTTATCATATATCTATGG CTACATGGTTATATTATGCTGTGGTTGCGTTCGGTTTTATTTACAGTTGCTTTTACAAAT ATTTGCTGTAACATTTGACTTCTAAGGTTTAGATGCCATTTAAGAACTGAGATGGATAGC TTTTAAAGCATCTTTTACTTCTTACCATTTTTTAAAAGTATGCAGCTAAATTCGAAGCTT TTGGTCTATATTGTTAATTGCCATTGCTGTAAATCTTAAAATGAATGAATAAAAATGTTT CATTTTACAAGAGGAGTGTATGATAAATAT bcftools-1.21/test/csq/ENST00000218032/ENST00000218032.fa.fai000066400000000000000000000000211467060157400215100ustar00rootroot00000000000000X 16590 23 60 61 bcftools-1.21/test/csq/ENST00000218032/ENST00000218032.gff000066400000000000000000000023601467060157400211360ustar00rootroot00000000000000X ensembl_havana gene 21 16570 . + . ID=gene:ENSG00000101916;Name=TLR8;biotype=protein_coding;description=toll-like receptor 8 [Source:HGNC Symbol%3BAcc:15632];gene_id=ENSG00000101916;logic_name=ensembl_havana_gene;version=11 X ensembl_havana transcript 21 16570 . + . ID=transcript:ENST00000218032;Parent=gene:ENSG00000101916;Name=TLR8-002;biotype=protein_coding;ccdsid=CCDS14152.1;havana_transcript=OTTHUMT00000055784;havana_version=2;tag=basic;transcript_id=ENST00000218032;version=6 X ensembl_havana five_prime_UTR 21 107 . + . Parent=transcript:ENST00000218032 X ensembl_havana exon 21 110 . + . Parent=transcript:ENST00000218032;Name=ENSE00001907173;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001907173;rank=1;version=1 X ensembl_havana CDS 108 110 . + 0 ID=CDS:ENSP00000218032;Parent=transcript:ENST00000218032;protein_id=ENSP00000218032 X ensembl_havana CDS 12445 15567 . + 0 ID=CDS:ENSP00000218032;Parent=transcript:ENST00000218032;protein_id=ENSP00000218032 X ensembl_havana exon 12445 16570 . + . Parent=transcript:ENST00000218032;Name=ENSE00001130430;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001130430;rank=2;version=6 X ensembl_havana three_prime_UTR 15568 16570 . + . Parent=transcript:ENST00000218032 bcftools-1.21/test/csq/ENST00000218032/start-lost-del.txt000066400000000000000000000005041467060157400222560ustar00rootroot00000000000000107 CATG C inframe_deletion&start_lost&splice_region|TLR8|ENST00000218032|protein_coding 107 CATG C inframe_deletion&start_lost&splice_region|TLR8|ENST00000218032|protein_coding 12455 T G missense|TLR8|ENST00000218032|protein_coding|+|5F>5C|12455T>G 12455 T G missense|TLR8|ENST00000218032|protein_coding|+|5F>5C|12455T>G bcftools-1.21/test/csq/ENST00000218032/start-lost-del.vcf000066400000000000000000000006231467060157400222170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO X 107 . CATG C . . EXP=inframe_deletion&start_lost&splice_region|TLR8|ENST00000218032|protein_coding X 12455 . T G . . EXP=missense|TLR8|ENST00000218032|protein_coding|+|5F>5C|12455T>G bcftools-1.21/test/csq/ENST00000218032/start-lost.txt000066400000000000000000000002511467060157400215130ustar00rootroot00000000000000108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G 108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G bcftools-1.21/test/csq/ENST00000218032/start-lost.txt-l000066400000000000000000000002511467060157400217440ustar00rootroot00000000000000108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G 108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G bcftools-1.21/test/csq/ENST00000218032/start-lost.vcf000066400000000000000000000005341467060157400214560ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO X 108 . A G . . EXP=start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G;type=ENST00000218032:12924826-A-G bcftools-1.21/test/csq/ENST00000227471/000077500000000000000000000000001467060157400166475ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000227471/ENST00000227471.fa000066400000000000000000000335371467060157400210120ustar00rootroot00000000000000>11 11:67758555-67772472 GCCTGGGACTCCCCAGTCAGGACAGTACAAAATCTCTTTATTGCTCATTTTCTGTAAAAA ATCGTGGCTCTCGGCGGACCCTGGGGATAGGAGGTGCAAAGTGCGCTCACACGCGGCCCG GGTCCGCGGCCGAGAGCTGTGGGGATCTGGAGCGGGCCGGGTCGCAAGAAGACCCTGACC GTGCTCCGGCGCTGGGGCGCGTGCTAAGGGCCCGCGGGGTTTCAGCTGTATTTTCGAACC CCTGTGCTTGGCCGAGGGGTTCCCAAGGCTCCACTCCGCCTTGGAGGGGGCTGCGGAAGC CCGGAGGTGACCTGGGCTCTGGGAGGGGCGTCCCCAACGTGGGGGAGGGGAGACAGGGGC CTTTGAAGACAGCGCGGGACTCGGAGGGGGTCCCCCCGACCTCAGACGTGGTAAACTGAG GCCGGCGAGGAGGGAGGCTGAGTCCGGGGACCAGGCGGCCCCTCACTGCTCCTCCGGCCC GTCTCCCCCCTGCGCCTGTTCGTACGGGCAGGGCCGGCGGCCGAGTCCAGCGGGCTCGGG GCCAGGCCTGGGCCCTGCGGGCGGCGCCTCCTCCTCCGCGCCGTCCCCATGCTCGCCCTC CGCGTCGCTCTCGTCCGAGTTGTCCTCCTCCAAGTAGCGGTAACCGCGCACCTTGTGCTG GGGCCGCGGGATGCGGGGCTGGCGCGGGGCCACGCCCCGGCGCAGCTTCTGCTCCATCCG CAGGTAGGAGACCGCGGCCGCCACCAGCGTCACCAGCAGCACCGCCAGCTTAGCCTGGGC GTAAGGAGAGGGATGCCAGGGACCCGCGGCCGCCTCGCCCCGCACCTTCCCCGCCTATGC CCCTCGCTGAGATAGGCCCTTCCCTCCTCCGGGAGCCTCCCGGGCCACGCGGCCCTCAAC TTCTCCAGCCCCTCCACCCATGCTTCCTGGACCGCCTCCTGCAGGCGAGGCTCACATCCA GCACTGTCCCTTACAGTCGCCACGCCCCTGGCGACCTCAGTGTCCCACACTGTAAGGGGA CAATGCAAATCCCTTTGCCTCATAGGGTGCATGCGCCAGTGTTGATAAAGTGCTGGCCAC AGGCCCTGCCTTCCCAGGGCTCACAACACTGTGTCCCTGACACACCCGTGGGCTGTAGTG ATGCTTTTCATGGGGTTTTGACTATAACCCGCAGTCAGGAATGATTTCACACCATAGCCC AGTACATACACACATATCTGTATGCATACTTCCTGCTCTTTTCTTTTTTCCAGACACGGT CGCTCCGTTTCCCCACCGCGCCCCCTCCCTCCCTTCCCCCACCCACTGCTGGAGCGCAGT GGCACGCTCACTTCAGCCTCAATCTTCCAGGCTCAAGCCATCCTCCCACTTCAGTCTCCC AAGTAGCTGGAACTACAGGCACACGCCACTACGCCCAGCTATTTTTTAAATTTTTTGTAG AGACAGGGTCTCCTATGTTGCCCAGGCTGGTCTTGAACTCCTGGCCTCAAGCAATCCTCC TGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCATGCCCAGCCCACTCA CTGCTTTTCTTTTTTTTTTTTCCTTTTTTTTTTTTTTGGAAGACAGAGTCTCGCTCTGTC CTCCAGGCTGAAGTGCGGTGGCGCGATCTTGGCTCACTGCAACCTCCATCTCCCAGGTTC AAGCCATTCTTGTGCCTCAGCCTCCAGAGTAGCTGGGATCACAGGGACGTGCCACCATGC CCAGCTAATTTTTGTGTTTTTAGTAGAGACAGAGTTTCACAGCCTGTTACCCAGGCTGGT CTCGAACTCCAGATCTCAGAACCCCCACCTCAGCGTCTCAAAATGCTGGGATTACAGGCG TGAGCCACTACTGCCAGCCCACTCCCTGCTATTTTTAGTTCTATTTTTATTTTTATTTTG AGACGGAGTTTCGCTCTTGTTGCTTAGGCTGGATGGAGTGCCAACGCCCCGTCTCGGCTA ACTGCAACCTCCGCCTCCCAGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGT GATTACAGGCACCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACGAGGTT TCACCATGTCGGTCAGGCTGGTCTCAAACTCCCTACCTCAGGCAATCCACTCGCCTCGGC CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTTTAGTTCTATTTTT AAAAAATGTTTAGCAACTGGGACTTGCTAGACCGAGCCACCATTTTTTGTGAGCAGAGCA TGAGGAGCCTGCTCCCCTTCAGGCCATGAAGAGAGACAGACCCAACATCTGGAGAACAAG GTACCAAACAGCCCACAGGATGGCTGTGATGCACCCACAAATCCCCTCAGAGATGGGCAA ACTGAGACTGGCTGGAGGTGGGCCAGTAAGTGGGGTGCTGAGTTGGGGGCCACCCAGTGG GCTGCAGGAATGGGGCCTTGGCCCAGAGACTGGCTTGGGAAGGGGTGGCATTTAGGAAGC TGTGAAGCCAGGGCAGGGGCTAAGGAAGTACCTGTCATTGGGCATGGGGCCCCCAACCCT GCCCAGTCTCACCTTCATGTGCAGGCTCGAGCCCAGGTACACGGTGAAGATGGCCACAGC CTGCCACCAGTGGTAGATGGTGAAGATGAAGTCCTGTCTCTCCTTGTCTTCGTACAAGAT TCCCAGGAGTGCTGCAGGCAGGCAGTACAGGGCAGGCAGGGGAGAGGTGTCACCTGGGGC CTGGGGCTACCGAGCTACCATCTACGAACTTTACTAAGCCCTGTATGGGTCCCAGCCCCG GACCAGAGAGCGCCTAGAAAGTGCTGTGAGGCGGTCCTGGCCTGCCCCCTGGTGGAGACC CTGGTCACCACACTGCTCACACGCTAAGCAGAAGTAGGAGCAGGTGCCTCGGGCTGTGTG GATGCAGGTGTTCCCGCTCCGCACCACATGCGTGGCCTCAAAAGAAGAAAGCTCTGTGCT TAGTCATGTCCTGTCCCCAACCCAGGTGTGCAGTGCCAAGCTTGCAGGCGCTGTTTCTCC TCCTCAGCCAGGACTAGAGAGATCGAACTGTTTGCAGCTGCCAACTCTGCAAATCAAACC TGAAGCTAAGCATGGAGAGGGGGGATTCCTTTCCAGTGAGTCCTCCCAGGGTGGGCAACA AGAGTAATGGATTGGGAGTCAGAAGATGCACGCTCGTTCTCAGGGCTGTAATGTTGGCTC TGTGGGTGATTTGGGTACTTAACTCCCCAGAGCTGCTTTTCCCAATGGTGAGATGAGCTT ATGCCTATTGTGTGCTGTGTTCTGAAGTTCTAAAGTGAGAAAGTGGGCATGGCACCTGCC AAATCATAGGGGCCACTATTAACACCTTCACCAGGCACTCAGGATATGAACACTCCTGTT TTGGGGCCCTGCAGGGTGACTTTACCCCCACAGTGCTGCTATGAAGAGACAAGGACCCCC CGGGGTTCACCGGAGGAGATGGGATATGGAGCTGGGCAGAGGGGATGCCAGGACCAGACA GGGCACAACATGGGTTCAAGATACCCAGGCTGGACTCTGCCCAGAATTGGCTATCCTTGG GCAAAACGGCCAAGAGACTGTGGTGCAGTATGAGGCTCCAGCCCCTGCTACAGACAGAGA CACAGAGCCAGCCTCCGCCCTGCCAGCAGCAGGCATGACCTCGGCTACTCCACACCCCCA AGGATGACGTTCAAAACTGTTCACAGCTTCGGCCCATCAGAACAGACACTGACATGGATG CCCGGCAGGACTGCCCATGTGTGCTAGCTGTGTTTCACTGCGTGTGCCCATCTGTGGTCA GGGAGCATCCTGGAGCTGAACATGGGCCCACCCGCTGCCTTCTGCAAACAGGGCCCTGTT CCCCAGCAGCCCAGACCTGGGGCCTGGACTCTGGTACTGAGCAGACTGGGTTGGGGCTGC AGGCCTGCTCCTCTCTATACAAAGGCCCATGTCTGTATCTATGCCATGGGTGTACAACAG GCCACTTGCTCCTACCACATGCTCCGTGAAGCAGAGACCAAAACATCTGCTCCAAGTGTC ATGAAAACTATGCCAGGGTAAGCCCTGTCCCCTGGTATGAAAAGGGAGAATCCCTGATGT GTTTTTCACACTGTCCCTAAGGGGTGTCCACAGAGCCCCACACCTGCCCCATGTAGCCAC GAGACTTCACACTGACCCTCCAGTGTTGATGGGGCCCTGTGCCCGCTCTGGGGTATTAAC AGAATGTCCATGGCATGGAACCCCCATACCTGTCTCCAGGGTGTCCACACCCTACCCATC TGTCCCCAGTGTGTCCATAAGACTTCCCTTCCACCCCCGGAGTGTCCACAGGAAGCCCCA CCTGCCTCTGCCATGTCCACAGGACCCTATGTGACCATGGGACCCCATATCTGTCCCTGG GATGTCTATGTCTCGCCAACCACCCACAGATAGCCATAAAGCCCCCTGCCCCGCCCCCCC CCCCCCAGTGCCCACAGCTATACTCACTGCTGAGTCCAGTCTTGTTCAGGGCACTGCCCA CACCCCAAAGGGCAGCTGCCACATAGAGGATCCAGCTGTGTTGCAGGACCCGAGGCACAG GGGCCCAGAAAAAGAGGATGAAGGTGAGCAGCAGGTGCACCCCTGCTCCGGCCACCAGGG GCACCGGGCGTGGCAGCCACAGGCCCAGCAGGCCCAGGAGTGAGGCGGCTGAGGCGCCCA GGCTGTAAGCCACGAGGAGGTAAGCCAGCCGCTCCAGCCCCACCGAGCACACGCCATAGC CCTGCGGGGGGACAAGGGGTGAGTGTTGAAGTCTGGAACAGCCCAGACCACAGTCTCAGC CCTCCCCGCATCGCGGGGGTGCCTCACCCCCCTGCGATGGGGGTCCTAAGAGCCAGGGGG GAAGAGGGTCTGGCTCTTACTCCCCGCATCGTGGGGGGTGCCTCACCCCCCTGCGATGGG GGTCCTAAGAGTCGGGGGGAAAAGAGGGGTTGGCTCTTACTCCCCGCATCGCGGGGGGGT GCCTTACCCCCCTGCGATGGGGGTCCTAAGAGCCAGGGTGGGGAGAGGGGCCCCCCGCGA TACGGGGAGTAAGAGCCAGGTGGGGAGAAGGGCTGGCTCTTACTCCCCACAAGAGGTGTT CCTTAGGCCACACCCTGCCCTCCCTGGACTGCCTGACCTCGCTCCAAGGCTCAGGGGAAG GTTCTGAGGGCAGGTGTGAAAATGCTTGGAATGTCCCTAGACACCGTGGGCTGTACCCCA CAAGGAACTAAACACTCTGTGGGTGCTATCCCATTTCGATTCAGAGAAGTTAAAATAACT TGCCCAAGGTAAAGGGGGGACGGGGGTAAGAGAGGGAAGAGAAAGCAGGAGGGGGATATT TGGGATATACATGTACACACTTACATATGTAATTAAAAATTATTCTTTGTTTACTTGAAT TCAAATTTACCTGGCTATCTTGTCTTTTGTCGGGCAATCCTTTGCAGGCTGTACTTACCA AGGCGATACCAGTGCAGGCAAAGAGCACCTCGAAGCCGCTGTAGATAAAGAAAGGCACGA GGTGGCGCAGGCGGTAGTCACGCACGTGCTTGAAGGGCAGCTGGAAGATGTTGCCCCAGC CCACGCTGCGCAGATCGATCTCCTCCGTGGGCCGGTAAGCGGCTCCGCACAAACCCAGCA CCTGCGAACCCATTACTTGAAGGGGCGGCCAGCCAGGCCCAGGCCTGGCCTCCAGGCTTC AGCCCCGCCCTTCAGATGCACCACGTGCCTGGGCCTTGCCCCAGCTCGGCCCCGCCTCCC AAACCAGGGCCCCGCCCCTGAGACACTCCCACAGACCCAGGTCTTGCCTTATCCCAGCTC AAGGCCCCGCCTCTCAGCACAAAGCCACGCCACCACACTCCGAAAGACGGTGGTCTTGCC TCCCAGCCCAAGGCCCCATCCCCTCTCTCTCACATACACACACTTCACAACTCACATTCA GACAAATCCATAGACTTCAACCTTCCTTCTCAGCCCCGCGCCAGACCTCAGCCCCGCCTT CCAGGCTAGTCCCCGCCCCTCGGACACACCCACAGACTTCGGCCCCGCGTCCCAGCACTA GGCCCCGCCTGACACAGCCACGGACTGGGCCTTGCCTCCCAGCTCCATCGCCAGGCTGCA GCATGCCAACGCCTTAGTTCTGCCGTCCAGTATCACTTCCAGTTTGAGCCACACCTTCCA GCCCTCACCCTTGGTCCTGTCCCCAACCCCCTCACAGGTCTCAGTCAGTCTTCTAAGATC TTGTCTCCAGCTCGAAACTGTGGACCAAGCCTGTTCCCTCCTTCCCCTGGCCTCTGGATG CCCACGCCTGCCTCGGACCACAGGCCTCAGCCCCGCCTCCGAGCCTCATGCCCGCTCTGC AGCACTCGGCCCTAGCTCCCCAACTCAGATCGCGCTCCCAGGCCTACGGCCTGCCCCGAG GCCACAACCCGACCCAGGCCATGCCATCCGATCCAGACCCTTTCTCGCAGACTCGGTCCC CAGAACCACACTCTGCTTCACTGACTGTCCTGCCCCCATCCCGGGCCGCACCAGCAGCAT GGCCAGGAAGCCACTGCCATGAGCACGCTCTCCACCACAATGAGGTTTCCGCTCCGCGGG AGCGTCCGCAGAACCGTCTTGTTGAAGCCGCTGAGGATCCCGTGGCTGTTGGTGCCTGGG AAGGGTGGGGGTGAGGGCACCGTGAGCAGAGAGTAGGGCACACAGTCAATCCAGCCACCA GGGTGGAGCCACGCAGGCCGCGGAGGAGCGGTGGAGGGCGGGAGAGTGAGAGCAAGGGCA GAGTTCCTTCAGAGAGCAGTTTGGAGGTTTGGACCACTGGGGCTGGGTTTGGACCACTGG GGCTGGGTGTTCCCCGGGAAAGGGGCATCTTTCCCCTGCTTCCCACCCTATTTCCCCAAG GCTCAGTGGACCTCACATTTCCATGCACACCCCCTGCACTGATTGAGCTCTGACTGTTTG CCTGGCCCCAAGAAAGATCCCACTGGCAGCCTCAGCCCAGATGGTGCCTTCTCCAGGCAG TCTTCCCCGCCCACCCACTCTCCTGGCTGGGTCAGATGTCCTAACTACTTACTCCTACAG GGCCCTGTGTCTTGCCCACCAGAGCCGTGGGGCACTGGGCTGCCAGCCCTGAATCCTGTG AGTGAGGGCCCAGTGTCTGCTGGGGAAGTAAGCAGGCTTTGTGGACTCCTCCCCAACCCC CAACAAGGACTAACCGCAGCTCTGCACATTGTACAGCGTGTGGTTCAGGTCATACAGGTA GTGGTTCAGGAAATAAATCATGGGCAGCTGGGCGCAGGCGAAGCTCAGCTGCAGAAACAA GGGCAGTTGGGACCAGACTCAGGCACAGAGCCAGGCAAGGGACACAGGCATGGTCTGGGG AGGGGTCCAGGCACAGCCTTGGGGGAACAGGGGCCTTCCCAGTTCTGGGAGTAGTGTGGT TACAGGGCCGCCCAATGAGGAAGACCTCCTCCTGGCCAGCATTGTGGAAAAGGGCAGATG AGATCTCTATCTCTATGGATGAGCAAGCTGGGGTGGGCTCAAGAAAGGAAGATGGGCAGC CTGGGCAACATAGTAAGATCCTATCTCTACAAAAAATAAAAAATTAGCTGGGTGTGGTAG CACACGCATATGATGCCAGCTACTCAGAAGGCTGAGGTAGGAGGATCACTTGAGCCCAGC AGTTCAAGGTTGCAGTGAGCTGTGACTGCACTACTGCACTCCAGCCTGGGCAACAGTGCA AGACCCTGCCCCCAACCCCCACCAAAAAAAAAAGAAAGAAAGAAAAAGAAATGAAGGTGG GGCAGATACAGTGGTGTGCGCATGTAGTCCCAGCTACTTGGGAGGCCAAGGTGGGAGGAT CACTGGAGCCCAGGAGTTCAAAGCCATCTGGGCAACATAGTGAGACCAGGCCTCTTAAAA ATAACAATAATAAAAGAAAGAAAGTGGGACTAGAGGGTTGAGACTGTGGATGGGCTCCAA TGCGTGGGTCTGCCCCTGCCACCCAACAATGGCCCACGTGGCACTCACATGGAAGAAGCT GTAGAAGATGGCTTGGAAGACCAGGAGATAGGGCGCGTGGGAGCCCCGCGGAGGCCGCTG CTTCATCCCCTGCCCATCCTGCTCCTTGTAGTGGGAGTACTCATGGTACTTCTGCGCCAT CCTGGACCACAAAGGAGAGAAGGCTCTCCCCAGCCCGACCTGTGCCACTCCTGTGTGTCC TGCACCCAGAGCTAGGAGCAGACCAGCCCCGGTGTGGGGAAACTGAGGCCCAGAGGGCGG AAGGGGCTTCCTGTGGTCCCCCAGCCAAAGTTGGCAATAAAGTGGAGGCTTGGCCAGGTC TCCAGCCTCCTGCCCTGCTGCCCACCAGGCTCACCTGGTGATGTAGTTGCCCATGGAAGC CCAAAGAGGCACGATGGCCATGCCCAGGGCCACAGCCGAGGGCACAAGCGTGTAGTAGCG CTCCCAGTAGTTGGTGGAGACAAAGAGGGCGTAGATGCCCACAGCGAGGAACATCATCCA CTTCGTTCCAAAAAACCTGCGGACAGTGGGAGAGATGCTGGCACCACAGGCCTGCTGGAC CACTGTGGCCTGAAGCCAAACGGGGCCACAACCGCAGGTCCCAGCTCACAGGGCTTTGTG AGGTAGAGAGAGTCGAGGGCACTGAGATGGAATATCAGATACACAGACTTGCTGAGTGGC CTCAGGCAAGCTACTGTGCCTCAGTTTTCCCAGCTGTAATATGGGCACGGAGCCCAAACC ACAGGCCTCTCATCACCACTGTGAGGATGGAGAGTGACCCATGGGTGTAACCAGCCCTCA TGCGTGTTCTGGGCTCTCTGATTCTCCCATTCCCCCTTCTCCTCCCAAGCTCATGCACTG TGTCTGTAGGGCCCAGGGGCTTGACTCAGGCTGGGAGAAGAGAAAGGAAGAGGCCCCACT GCTGGGAGCAGCAGAGCCAGAGTCCCGGCACCCCTGCCTCCAGTCCATTGCTTTTATGAA CCATGGTGGTCAGTCAGGAAGTTTCCACCTCTCTGGGTCTGGGAAAAGGTCACACAGTGA CAATAGAAGGGGCTTGGTGAGTGACAGGATGAGGGCTCAACCACCCATGGAGGCTGATCA GGCCAAAAACCACTACTGGTATCTTCAAGTTTTCTGTATTTATGCTCCTTAAGTAAAAAT GCCAGTAAAAATGTGCATTCACTGCTGGTGAGGATGTGGTTTGAAAGTGGCACATATAGG CCAGGCACAGTGGCTCACATCTGTAATTCCAGCACTTTAGGAGGTGGAGGTGGGCAGATC ACCTGAGGTCAGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCACCTCTACTAA AAATACAAAAATTAGCCGGGTGTGGTGGTGCACACCTGTAATCCCATCTACTTGGGAGGC TGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCCGTGAGCTGAGATCGCGTC ACCGCACTCCAGCCTGGGCAACAGCAAGATTGCTCAAAAAAAAAGTGGCACATATAGCCA GTGGTCACACACACTGGCATAACCCTTTGGGAAAGCAGCCTGGTAGTTTTGGCAGGGGGT GAACATGTGGATTTGAGTCCCTCTACTGGGGTTCAAGCCTTCAGTCTGCCAGTTACTGCC TGTGGGACCTGGGCAAGTTGTTTAACACCATGGTTTCTTCATGTCTAAGACTGGAGCAGC TTCCTCAAATTATTGGGAATGAAATTGCGCTTATAAAGTGCCCAGCACGGCCGGGCGTGG TGGCTCGTGCCTGTAATCCCAGCACTTTAGGAGGTGGAGGTGGGCAGATCACCTGAGGTC AGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTTTACTAAAAATACAAAA AATTAGCTGAGCGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGG AAAATCGCTTGAACCTGGGAGGCAGAGGTTGGAGTGAGCCGAGATTGTGCCATTGCACTC CAGCCTGGTGATAGAGTGAGACTCCATTTCAAAAAAAAAGTAAAAATAAAAATAAATAAA TAAAATAGAGTGTCGGGCAGACAGGAGACAAGAGTTCACTGCTATTAGTAGAAGTGATAG GTTTCAAAAGCCATAAAGCCTTTTGTATGGCTTGGACCTAGTAAAGACATTGTTGAAAAT GTATCCTAGGAAAAATAATTGTTTAAAAAATTGGGGGAGTGCTGGATGTGGTGGCTCACA CCTGTAATCCCAACACTTTGTGGGGCTGGGGCGGGTGAATTTGAGACTGGCCTGAGCAAC ATAGCAACTCCCCATCGCTACAAATACTTTAAAAATCAGCCAGATGTGATGGCGTGCGCC TGTAGGCCCAGCTACTCGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAGTGTGTGGGG GTTGAGGAGGCAGTGAGCTGTGTTCGTGCCACTGCACTCTAACCTGGGTGACAGAGTGAG ACTCTGTCTCAAATAATAATAATAATAAAATAAATAAACACATAATTTAAAAAAAAAAAA CAAGGAAACAGATGTAAGCACAGAAGGAACTGCAGTGTCCAATTCCAAGCCACTGTTCAG TGCCACCGTATCTGCAGAAGATGCTACCATTGCAAAGTCGTAACTGTGAAGGCTGTAGAG TAGGCTAAGATATGCTCAGTGAAAAGAAGGAAGCAAGCTCTGGGCACTGTGGCTCATGCC TGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGAATCACTTGAGGTCAGGAGTTTAAG ACCAGCCTGGTCAACATAGTGAAACCCCATCTCTACTAAAAGTACAAAAATTAACCGGGT GGCAGGCGCCTGTAATCCCAGCTACTCAGGGTGCTGAAGTAGGAGAATCGCTTGAGCCTG GGAGGCAGAGGTTGCAGTGAGCCGAGATCACACCACTGCACTGCAGTCTAGGTGACAGAG CAAGTATCTGTCTCAAAAAAAAAAAAGTAAGCAAGCAAAAGCAAACATAGCCCGCTTGCA TACACACACACACACACACACACACACACACACACACGGGCACGTCCACACACGTGCTCT GGGGACAAGGATGTGAATGTAATCCATGCATGCTGGTGGGACAGCATGGGTAGCCGATTT CCTGGAGGGCTTAGATGGGGTTTCTTTTTTATGATTTCAGTTATTCTAATCCTGCCTGTG CAACGGGAGATGTTTTAAATTTTCAAATTTTTGTTTAAATGGAGTTTTCTCTTGTTGTTT TGTTTGTTTGTTTGTTTTAAAGATGAGGGAGCTCAAATTCACCTAATTTGTCCACTGGTC TCCAGGTCCCATCAGGGAGGGCACTGTGGACCGGTGATGGGGAGGCTGAACCACATACCT CCAGGGCTCAGATCTGGGGGAGAGCTCTGGGGCACCTGCCCAGCCATGCCTGTCTGTGAG AAACACCCCCTCAGCACCAGTCACAGCGACTGGGCCAGGCATGGGTGCCTGGACTTTGCT GACCGATCAGAAACCCCTAACTCTACAGCCCCAACCCTGAAGGCCACAGTGGCTCTGGGA GGCCTCCAAGGAGGCCACGAGGAGGGTGCCACGTGAGGCCCAGGCAAGCTGGGAGGGAGC TCAGCCCGTGTGAATCTGTTGCTGGAAACCAAATGTGCCCTGAGGCAAAGTTCCTGTTTC CTTCCCCAAATCCGAGTTTCACCCCCTTCACTCTCAGGCTTCCGGGTAGAAAAAAACCTC TCCCTTGTTCCCTCGCCCCACAAACACCCCGGCAGATGGACACCTCCTGGCCCGCCGGCC TCTGTACCCCTCCGAAATGGGAGTACCGCAGCATCCCACAGGAGCAGCCGCGCCCACCTG ATGAGCACAGGTGTGTAGAGCAGGGCGGCGATGGGAGTCACGTTGATGCCCATCAGCATT TTGCTGTCGATGTCGGGCAGCCCCATGTTGCCATACTTCACCTCGCGGTAGGTCTCGTCG TAGTGCAGGATCAGCTGCATCTGCAGGAGGCCTGGGGACAGGACAGAGAGCGGCGTGCAG GGAGCAGCCTAGCTTTGGGCGCCACCGAGCAGAAGACGGCATGCAGGCCTCGCAGGGAGC TCCAATCACCGAAGGCATTCCCGCTGACAGCGCCCCTCAGGACAGCGGGGTTCCCGGGCT GCGCCACGCCTTCTGCCAGCCCGCGGCCACTTGGCCAGCTAAGCCCAGACCCCCACCCGC CTTGCTCCGCCGGCCTCCAATTCTGACGGTGGCAGGTCTGTCCGGGAGCCCGGACCCCCG TCCCCCACCCACACCGAGGCTCTGGCTGGGACCCGGGGACGCTGCGCTACTTGACCCCCC AACCCCACCCCCGCCGCGGGGGGCCGTGGCTGCAGCTGCGAGGGCAGCGGAGGGGAAGTG AGAGCGGGCGGGAGGCGGCGGCCCGCGGTTTCTGTTTCCCGGGCCGGGCTGGGAGCGGGC GGGGCGGCCCCGGGTCCCCGAGCGGCACCTACCCAGGTAGACGCCGTAGGTGAGCATGCC CCCGGCGCTGGCAGCCAGCACGTTCTTGAGCACGCCCAGGCGCTTGCGGCGGTAGTAGCG GCGCTCCTCCTCCTCCTCGTTGTAGTTGGGGTACGCGCCCACCAGCTCGTCCAGCTGCGA GCCACGCACGCCGCTCGCACCCGCGATCGCGCCCCGAACCCGTGTCCCCCGGTGCCCGCC GCCCCCCGGCCCGCCCCGCCCCCGCCGGGGGGACCCTGGCCCACAGGGGACGCCCGCGCC TCGCACTCCGGGTCCCCGCTCACCGGGGCCTCGGGCCCGTCCGGGACCCCGAGCAGGTCC TCGTCGCCCTGCGGCCCCGCAGCCCCCGCCATCGGGTAGAGCGGCGGCTCCGCCTCCATG GCCCGAACTACTGCGGACTCGCGGCGGTCGCCCCGGAGTCCCTGCGACCGCCCGGCCACT TCCTCCCGGCGGCCGGGACCTGCCCCCGCCCCGCCCTGTCCCGCCCTGCGGGCCGCCTCC TCCAGGACACGTGTGTGTGTATGTGTGTGTGCGCGCGCGCGCGCGCGTGTGTGCAGGGGC CTGCCTGTGTGTGCCCTCTGGGGTGTGAGTTCGAATCCCCACTCAGCCACCTCCTGGCCC TGTGACTTTAGGAATTAACTCCATTTCTTTGTGCCTCGGTTTCCTCCGTTTCCTCGACGG TAAAACAGAAATACATGGCACTACCCCCGGGGCCATGGCGGAACTATTGAGTTAATGCAA AGCCTTGGAAAAGTGCCAGGGTTGCCTGGCTCCCTTAAGCTCCCCTCAGGGTTGCCTGGG TCGTCCCCAGCCCCACCTCCAAGCCTGCTGTTACAGCTCATCAAAGAGCACTGCAGGGAC AGTAGCGTCACCACCTGGACCCCACCTCCCACCACCGGACGCTACAGCCAGAGCCCACCT CCCATGTCCCCATCCTGCTCCAGTTTGGGCTGTGCAAATGGGAGCTTGAGTGGGTCCTGG GAGGTGGAGATTGTGATCCCCACTGAACTACATGGGGGACCCTGCCACAACCATGTAGTG GGGCCCAGAGCCACCTGCCCCCATCCTGCTGGGCACTGGATCCCGGGCTGCAGCGGGAGC CTGTGGTGGGGCCGACACTCCAAAGCACTGGCTACCACCGACCTGGCTGGAGCCACGGGG CCACTTTTGAAAATATCCAGATTCTCTCCCCTGGGTTCCTTCTGGTTTGAATGCTCTTCC TGCTGCGCCTCCCAGGTGGCTTCCTTCCCACTCAGCTCTCAGAACAAGAGACCATCCCTG CAGAGAATGCAGTCCCTTCACTTCCCTTCTGGTTTTCCATGCCCTCCCTGTGCACCCC bcftools-1.21/test/csq/ENST00000227471/ENST00000227471.fa.fai000066400000000000000000000000221467060157400215270ustar00rootroot0000000000000011 13918 25 60 61 bcftools-1.21/test/csq/ENST00000227471/ENST00000227471.gff000066400000000000000000000100331467060157400211500ustar00rootroot0000000000000011 ensembl_havana gene 21 13898 . - . ID=gene:ENSG00000110057;Name=UNC93B1;biotype=protein_coding;description=unc-93 homolog B1 (C. elegans) [Source:HGNC Symbol%3BAcc:13481];gene_id=ENSG00000110057;logic_name=ensembl_havana_gene;version=3 11 ensembl_havana transcript 21 13039 . - . ID=transcript:ENST00000227471;Parent=gene:ENSG00000110057;Name=UNC93B1-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000227471;version=2 11 ensembl three_prime_UTR 21 462 . - . Parent=transcript:ENST00000227471 11 ensembl exon 21 774 . - . Parent=transcript:ENST00000227471;Name=ENSE00003679014;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003679014;rank=12;version=1 11 ensembl CDS 463 774 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 2593 2711 . - . Parent=transcript:ENST00000227471;Name=ENSE00003531573;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003531573;rank=11;version=1 11 ensembl CDS 2593 2711 . - 2 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 4528 4801 . - . Parent=transcript:ENST00000227471;Name=ENSE00003665994;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003665994;rank=10;version=1 11 ensembl CDS 4528 4801 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 5519 5701 . - . Parent=transcript:ENST00000227471;Name=ENSE00003597638;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003597638;rank=9;version=1 11 ensembl CDS 5519 5701 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 6592 6609 . - . Parent=transcript:ENST00000227471;Name=ENSE00002485200;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002485200;rank=8;version=1 11 ensembl CDS 6592 6609 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 6612 6715 . - . Parent=transcript:ENST00000227471;Name=ENSE00000824041;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000824041;rank=7;version=1 11 ensembl CDS 6612 6715 . - 2 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 7275 7368 . - . Parent=transcript:ENST00000227471;Name=ENSE00003692215;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003692215;rank=6;version=1 11 ensembl CDS 7275 7368 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 8089 8221 . - . Parent=transcript:ENST00000227471;Name=ENSE00003650035;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003650035;rank=5;version=1 11 ensembl CDS 8089 8221 . - 1 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 8435 8596 . - . Parent=transcript:ENST00000227471;Name=ENSE00003682505;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003682505;rank=4;version=1 11 ensembl CDS 8435 8596 . - 1 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 11938 12091 . - . Parent=transcript:ENST00000227471;Name=ENSE00003663353;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003663353;rank=3;version=1 11 ensembl CDS 11938 12091 . - 2 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 12573 12714 . - . Parent=transcript:ENST00000227471;Name=ENSE00003644518;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003644518;rank=2;version=1 11 ensembl CDS 12573 12714 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl CDS 12864 12959 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 11 ensembl exon 12864 13039 . - . Parent=transcript:ENST00000227471;Name=ENSE00003655820;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003655820;rank=1;version=1 11 ensembl five_prime_UTR 12960 13039 . - . Parent=transcript:ENST00000227471 bcftools-1.21/test/csq/ENST00000227471/insert-splice-vs-frameshift.txt000066400000000000000000000002371467060157400247470ustar00rootroot000000000000006609 A AG splice_acceptor&splice_region|UNC93B1|ENST00000227471|protein_coding 6609 A AG splice_acceptor&splice_region|UNC93B1|ENST00000227471|protein_coding bcftools-1.21/test/csq/ENST00000227471/insert-splice-vs-frameshift.vcf000066400000000000000000000007201467060157400247030ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 11 6609 . A AG . . EXP=splice_acceptor&splice_region|UNC93B1|ENST00000227471|protein_coding;type=ENST00000227471:67765163-A-AG, ambiguous case in 2bp intron bcftools-1.21/test/csq/ENST00000230048/000077500000000000000000000000001467060157400166415ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000230048/ENST00000230048.fa000066400000000000000000001134211467060157400207650ustar00rootroot00000000000000>6 6:24667279-24705294 TTCGTCACAAGGGTGCGAGGAAAGTCAGTGAGCAAATCGCGGACCACCGGGGCTGCCAGC TCGCCTGACTCCCGGCCTCTTGCGCTCCTAGGGGCGGAGAAGGGTGCGGGCTCTTCGCCC TTTGTGTCCTCCTTCTTTCACTAACTTCTGGACTTTCCAGCTCTTCCGAAGTTCGTTCTT GCGCAAAGCCCAAAGGCTGGAAAACCGTCCACGATGACCAGCATGACTCAGTCTCTGCGG GAGGTGATAAAGGCCATGACCAAGGCTCGCAATTTTGAGAGAGTTTTGGGAAAGGTATGG GAAAGGTAGGGGAGAAGCCGTGGCTTCTAATGAAGGAAAAGAAAGCACCGTGCTTGGTGC CGTTGTGAGCTTTGAATAATTATCTCTTGTTAGGTTGTGTTCTAGTACGCCTGTAAATTC ACCTTAGTAATAATGATTATTACTTTAATGGAGCCCCTAAATATGCTGGGTCGAACGCGT AAGTTCTCTATCTAAACATAGATAAGTATGGTTATGACTCGTGGAGACAGTTCCAAGGCT GGGAGGGACTTTGGAGTTTGATCCTTCAACCAACAAACGTCTGCATTGCTCCAGAGAAGA GTAAGAGAAACCTCTGCATTTAAGGCACATTACAGTCTAATTCTCTAGGCTCTAGAAGAT TAGAAGATAAATAATTGCAATAAGGTACAAAAGCCAAGTGCTTGGTAGAGTGGTGAACGA AGGGAGAAGTTGTTCCTCTGTAGTGGTTTGGGAAATTTCTCAAAGGCACCCAACTCCTGA AGAAGTAAGTTAGCCCTTGGAGGAAGACTGAGTGCTTTTCTGAGACCAGCACTCACAAAG CCCGAAGGTGTTTGTTTGTTTTTGTTTTTTTAGGATGAGGTTTCGCCCTTGTTGCCTAGG CTGGAGTGCAATGGCGCGATCTCGGCTCACTGCAACCTCCACCTCCCTGGTTCAAACAAT TCTCCTGCCTCACTCAGCCTCCCGAGTGGCTGGGATTACAGGCATGCGCCACCATGCCCA GCTAATATTGTACTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGCTCTCGAA CTCCCGACCTCAGGTGAAACGCCTGCCTCCGCCTCCCAAAGTGCTGGGATTACTGGTGTG AGCCGCCACGCCAGACCTTGAAGGTGTTTGTTGTTGTTGTTGTTTTGAGATGGAGTCTTG CTCTGTTGCCCATGCGGGAGTGCAGTGACACGATCTCGGCTCACTGCAACCTCCGCCTCC TGGGTTCAAGTGATTCTCATGCCTCAGCCTTCCAAGTAGCTGGGATGATTACAGGCATGC GCCACCAAGCCTGGCTAATTCTTTATTTTTATTAGAGACAGGGTTTCATCATGTTGGTCA GGCTGGTCTCAAACTGCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCGAAGTGCTGG GATTACAGGCATGAGCCACCATGCCCCGCCAAAAGCAGGGATTTACTGAAAATGAAAGGA CACTCCTGTGTTTGGGGTGTGGAGCAGCAGCTCAGGGGCCCTAATACCCCATTGAAGTCT CCTATTGGCCACTTGGTACTCATCTCATGTAAATGAAGTGGTGACCCACAATTGGCTGTG AAAAGCAACCAATGAAAGGCTAAAGTGAAGTTACAAAGTTGCCCTTATATGCAAACGAAG ACGTGGCGTGCAATCAGATGGTGAAGTTACATAGTTACACTCCTATGGGAAGATCTGATT GGTTGCAGAAAGAATAATTTTTTTTAAGGGATAACTTACTTCTTAGCGTAATTTTGCTTT TTGCAACCAATCAGAGGTACTTTCAATTTCCCATCTGCCACACAGAAAAGGTGGGGGTTT GGAAAGGGAGAAGCCTCTGGTTCTTTTGTTACTTGGTGTGGGAAGTTAGGGTTTTACTTT CAATTTAGTTCTAGGAAGTCAGCGTGAAACAGCCCTAGGTTCCCTGCCTCCAGATCCGAT TCTCCTGCCTCGCTTGTAAGAAAATCATGCTCCATAAGAAGCATTTATAACTAAACCTTG TGAACCCCAAAAATTTGAGACAGGTATCAGTTAATTTAGAAAGTTTATTTTGCCAAGGTT GAGGATGCGCACGCAGTGACACAGCCTCAGGAGGTCCTGACAACATGTGCCCAAGGTGGT CAGAGCACAGCTTGGTTTTATGCGTTTTAGGGACATATAAGACATCAATCAATATATGTA AAATGAACACTGGTTGGGTTCGGAAAGGCGGGACAACTTGAAGCGGGAAGGGGGCTTCCA GGTCACGGGTAGGTGGGAGACAAATGGTTGCATTCTTTTGAGTTTCTGATTTACCTTTCC TAAGGAGGCAGTCAGATACACATTTATCTCAATGAGCAGAGGGATGACTTTGAATAGAAT GGGAGGCAAGTTTGTCTTAAGTAGTTCCTAGCTTGAATTTTCCTTTTAACTTAGTGATTT GGGGGCCCAAGATATTTTCCTTTACATTTGCCCCCTTTTCTTTTTTTTAAAAAAAATTTT TTTTTGGAGAAAGCATTTTAGAAGAAAAATGAGTCTTTGGTCCCAGATTTCATCTGATCG CTCATGCTAGGATGGTTTATTCCTAGACAGGTAAGTCCCAAGTTATTAGGAAAGCTAATT TTTAGAAGGCTGTGAACTCCCATGTCTTGTGAAGAGAAAATAGGGGGAGGAAGGGTGAAA AACAACAAACAAAAGAACAATCCTGGAAAATATACATAGGCCACGTTATTCTGAAGTCCA TACATCAGTAGGCAGGTATGAAAGTGGCTTATGCGTGTAAATAGGTTGCTGTTATTTTCT TCTGAAGTTTAAGTTGTCTAGCTTCAGTTTGCAGGGCTTTACAAAAGCACAGCTGTTTTC AGTGACTCCTAATTAGGAAAAAAAAGGAAAAGAAAAGAAAAAAATTAAAAATATTATTTT GGAGACTTGTAGCCAGGAAAAATTAGAATTCAGCCTAAACTGTAGAAAATAATAAAAATT GAAAAAATTAGGCAAGACTAGTATCTAACAACAAGTGGACTGTAAGTTTTGAAACAATTT TTCTCTCTCCAGTTTTCCATTTTTACTAAAGACAAATCATGGTAGGACTGATTTGCTTTA TTATATTTGACCAGATTATTTATATAAAGTGTAGCAAGAATAATTATTTTTCACATAGGC TTTTTAAAATTGGCTTTGAAGGAACTTTGTTCCATAGAAGGAATCTCAGATAAGATTCTT TTTAAAGCCAAGCTCAGCCATGGATTTGTACCATCAAATACCTATGAGTAGGGTGAATTT CCTCTTTTTGATGTTCCATGATAAACCAGGGGCTCCTGGACCTGTCAGAAAATGACATTC TTTACTTAGCACATATCAGAAACCCTGTACAGGGACTTTGTAAAGTGTGAGGCCAGTTTT CCCAAGGGCTTTTATTGGCTCCATAAGTCAGGTTTGATTACTTAAAGGAAAGTACACCTT TCCACTCAAAGCCTTGGTAAAATAATCAGTTTCTCCAACTGTGTCCTGTTACAAATGAAA ACAGATTCTTACTGCACTTATGCAAATAACTGTATTGGCACAAGTTAAGAATACTCACAA ATAGTTTACAAATTCTGGAGAAATCAGGTAGAGAGAAACAAATATGCTCCAAATTTTGTT GATTGGAGTATACTAAATTGTTAAAAGCTGTCAATAGCTCAAAAGAAAAGTTTCAAGGCT CTGAAAAACAAAGCAAAAGATCAGCAATGTTTAAGCAAAAAGTCAAAAAGATTAGTTCAG TCCCCTTAGTTAATTCCTATTCTGCTTGATATTCATGAGCATTTTAGCTCTCCATGAGTT CTGAAAGTTTTTCCTCTATTCTCATGTAACAATCTCCAAAGTTAATGGAGACCTGCATTC AAGAGGAAACAACAGGTGCTGGAGAGGATGTGGAGGAATAGTTACGTTTTTACACTGTTG GTGGGAGTGTAAACTAGGTCAACCATTGTGGAAGACACTGTGGTGATTCCTCAAGGATCT AGAACTAGAAATACCATTTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGATTA TAAATCATGCTACGATAAAGACACATGCACATGTATGTTTATTGCAGCACTATTCACCAT AGCAAAGACTTGGAACCAACCCAAATGTCCATCAATGATAGACTGGATTAAGAAAAAATG ACACATATACACGATGGAATACTATGCAGCCATAAAAAAGGATGAGTTCATGTCCTTTGT AGGGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTATCACAAGGACAGAAAAC CAAATACCGCATGTTCTCACTCATAGTTGGGAATTGAACAATGAGAACATTTGGACACAG GGCAGGGAACATCACACACTGGGGCCTGTCGTGGGGTGGGGGGATGGGGGAGGGATAGCA CTAGGAGAAATACCTAATGTAAATGACGAATTAATGGGTGCAGCAAACCAACATGGCACA TGTATACATATGTAACAAAACTGCACGTTGTGCACATGTACCCTAGAACTTAAAGTATAA TTTAAAAAAACAAATTTAACAAAGAAAACATTATCAAGAATAAATAATGAATCTCAAAAA ACAACAACAGCAACAACAAAAAAAAACACTTTCTAAAGAGGACCAAAACAACACAACAAT TGTGCGTGGATGACTAAAAGTTTTAGGGCAGCCATAGGCAAAGACACAATTGACAAGGAA ATTTGATACCTCTCCTCTGTAGCACACAATAATTTTAACGTAACAATTATGATTATTACT GATAATGTACACTAGGTCATATCAGAATTACAGGAATTTCCCATAATTTTGGAACACATA CCAATAACATATTTATACAAATACATCTCAAAGAAAGCCAAACACTGTTGCATATTTGAC AATGCTTCCTGTGTAATTTTTGTACCAAATAAGCCAAATTATGCCATTTTTGGACTTCAG GGAATCTAATATCTTAAAGGACTAATTAGGTCAGAAAAAGACATAATTTATAATTTGATT TTGGAAAGTTTGTCAAATATCAAATGTTTAAAACACCTGATATCACAAAAATAGGATCAC AGGTCATTATAAAATAAATCATTCATTTAACCAAAGTGATAACTCAAGGATTTCATAAAA AGGTGAAAACCTTCATTCTTTGAGAGAGGGGACTTAACTTTCCAAACAATAAGCCCTAAT AAAAACAGCATGAAGCTAATTAAATTTGTTTTCAAAATTTTATAAACAATCTATAAAATT TTAAACTTGACCATAAGATATAATTTCTAACTGGGCGTGGTGGCTCACGCCTATAATCCC AGCACTTTGGGAGGCCGAGGTGGGCAGATCAGGAGGTCAGGAGATCAAGACCATCCTGGC CAACATGGTGAAACCCCTTCTCTACTAAAAATACAAAAATTAGCTGAGTGTGGTGGCACG CGTCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAAGCCAGGAGGC GGAGGTTACAGTGAGCTGAGATTGAGCCACTGCAGTTCCAGCCTGGGTGACAGGGCGAGA CTCCATCTCAAAAAAAGAAAAGAAAACAAAAGATATAACTTCCATAAGCCTTTATAACCT TTATTAAGGAGTCAGTTAATGTGTCAAGAAAACCTTGTTAATCTGATTACAGGGGCCCAT AAGCTGATCTTGCATCATTGTGCCTTTGACGTTAATCATTAATTTATAGAGAAACTGAAC TTATTTTATCTTTCAAATTTGGACCTTACAGTCTTACCTGCCCACCTCTTCTTCGATAGT CTCTGGGCCTTGAGGAGTTGAATGCCTTTAATTTCTGGCCGTGTATCTCAGGAATGCAGT TTATTTTGATTGGCGTCTTCTACGGGGCCTGAAGATGACAGCTTCAATTGCTGTCAGTGT TTAAGATTTAGTAGGACTTGGTGTCCTTTTTAGACCCAGGAGTCAAAGCCCTGTAACCTA AGGTCACAAGGACTTTAAAAGCACATACAGGAAAATACCCAGTTGTAATCATGTTAATTA AAAAATCTTTTTTTAATCTCAGTTTTTTCCTAAACATAGGAATTATTTCAACAAAATGTA AACTCTGTTAGGTCAGTTACCAAAAAGCAAAAGAAAAGACCTTCTGCAATGCACAGAACA TGATGTTGGAAGAAAACACTTCCTTTAGACCTTTAAGACAGTGTGCCTTTTTAAAGGGGA GAGAAAGCTGAAAAAAAATGGCAAGATGCAATAAAAATTGAACTTTCAGTTTTAAAAAAA AATTAAATTCTCTTATAATTTTTTTTTTGAAATAGAGTCTCGCACTGTTGCCCAGTTTGG AGTGCACTGGTGCAATCTTGGCTCACTGCAGCCTCTGCCTCTTGGGTTCAAGCAATTCTT GTGCCTCAGCCTGCCAAGTAGCTGGGACTACAGGCACATGCCACCAGGCCTGGCTAATTT TTGTATTTTTGTTAGAGACGAGGTGTCACTACGTTGGCCGGGCTAGTCTACAACTCCTGA CCTCAAGTGATCCACCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCAGAAGCCACC ATTCGTAGGCAAATTCTCTTATAATTTATTAAGAGTAAGTTAACCCCTTAAGAAAAGTTT ATTTTTCTAACCAATAATTTCGTGTATATGTGTCTTTTTTAACATGAAGCCCAGTCTCTA GAAAGAGCATTATAATTTCCTTTTAATTGTAAACATGATCATATACAATTTTTTTAAAAC AAATCCTCTTATTGTGACATACACAGACCATTCATGACATGCTTGAACTTTTATCTTAGG ACTAAATTTACCATACAGTATTCTTTCTCATGTAAAATTATTTCTAAGCTTTCTTACCAC ATACAAAAAAAATTTGTTTTATAACTTCCTTTACAACATCTCTCTTATTTCCTGATTCCT TTACCTTGTTGTATACATAACCTTTAAATAAGTTTTGTGGGGTTTTTTTTGTTTGTTTGT TTTTTATCTGAGACAGAGTCTTGCTCTGGCACCCAGGCTGGAAGGCAATGGCCCGATCTT GGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCTCGAGT CGCTGGGATTACACGTGCACCACAATGCCCAACTAATTTTATATTTATAGTAGGGACAGG GTTTCACCATGTTGATCAAGCTGGTCTTGAACTGACTTCAAGTGATCTGCATGCCACGGC CTCCCAAAGTGCTGGGATTGCAGGCATGAGCCGCTGCCCCTGGCCTAAATAAGCTTTGAA TTAGACAAAACTTGTTCACCGTTTTTGGGGGGTTTTGTTTGTTTTTTTGTTTTTTTGAGA TAGAGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATTTCAGCTGAGTGCAGC GTCTGCTTCCTGTGTTCAAGTTATTCTCCTGCGTCAGCCTCCTGAGTAGGTGGGATTACA GGCGCCTGCCACCACGCCTGGCTAATTTTCATTTTTTGTATATTTAGTAGAGACAGGGTT TCACCATGTTGGCCAAGCTAGTCTCAAACTCCTGACCTCAAGTGATCTGACTGCCTTGGC CTCCCAAAATGCTGGGATTACAGGCATGAGTCAGTGCACCCAGCCCTAGAGTTCAACTGT TTTTTTATTTTCTTATTATACTTTAAGTTCTAGGGTACATGTGTGCAACGTGCAGGTTTG TTACATATGTATACATGTGCCATGTTGGTGTGCTGCACCCATTAACTCATCATTTACATT AGGTATATCTCCTAATGCTATCCCTCCCCCCTCCCCCCACCCCACGACAGGCCCCGGTGT GTGATGTTCCCCACCCTGTGTCCAAGTGTTCTCATTGTTCAGTTCCCATCTATGAGTGAG AACATGTGGTGTTTGGTTTTCTTTCCTTGAAATAGTTTGCTGAGAATGATGGTTTCCAGC TTCATCCGTGTCCCTACAAAGGACATGAACTCATCCTTTTTTATGGCTGCATAGTATTCC ATGGTATATATGTGCCACATTTTCTTATTCCAGTCTATCATTCATGGACATTTGTGTTGG TTCCAAGTCTTTGCTATGGTGAATAGTGCTGCAGTAAACATACATGTGCATGTGTCTTTA CAGCAGCATGATTTATAATCCTTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAAT GGTATTTCTAGGTGTAGATCCTTGAGGAATTGCCAGTGTCTTCTACAATGGTTGAACTAG TTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTATTTCTCCACATCCTGTCCAGCACCT GTTGTTTCCTGACTTTTTAATGATCACCATTCTAACTGGTGTGAGATGGTATCTCATTGT GGTTTTGATTTGCATTTCTCTGATGGCCAGTGATGAAGAGCATTTTTTCATGTATCTGTT GGCTGCATAAATGTCTTATTTTGAGAAGTGTCTGTTCATATCCTTTGCCCACTTTTCGAT GGGGTTGTTTGATTTTTTCTTGTAAATTTGTTTAAGTTCTTTGTAGATTCTGGATATTAG CCCTTTGTCAGTTGGGTAGATTGTAAAAATTTTCTCCCATCCTGTAGGTTGCCTGTTCAC TCTAATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTTTAGTTTAATTAGCTCCCATTTGTC AATTTTGGCTTTTGTTGCCATTGCTTTTGGTGTTTTAGACATGAAGTCTTTGCCTATGCC CTGAATGGTATTGTCTAGGTTTTCTTCTAGGGTTTTTATGGTTTTAAGCCTAACATTTAA GTCTTTAATCCATCTTGAATTAAGTTTTGTGTAAGGTGTAAGGAAGGGATCCAGTTTCAG CTTTCTACATATGGCTAACCTGTTTTCCCAGCACCATTTATTAAAAGGGAATCCTTTCCC CATTTCTTGTTTTTGTCAGGTTTGTCAAAGATGAGATGGTTGTAGATGTGTGGTATTATT TCTGAGGGCTCTGTTCTGTTCCATTGGTCTATATCTCTGTTTTGGTACCAGTACCATGCT GTTTTGGTTACTGTAGCCTTGTAGTATAGTTTGAAGTCAGGTAGCGTGATGCCTCTCCAG CTTTGTTCTTTTGGCTTAGGATTGTCTTGGCAATGCAGGCTCTTTTTTGGTTCCATATGA ACTTTAAAGTAGTTTTTTCCAATTCTGTGAAGAAAGTCATTGGTAGCTTGATGGGGATGG CATTGAATCTATAAATTACCTTGGGCAGTATGGCCATTTTCACGATATTGATTCTTCCTA TCCATGAGCATGGAATGTTCTTCCATTTGTTTGTGTCCTCTTTTATTTCGTTGAGCAGTG GTTTGTAGTTCTCCTTGAAGAGGTCCTTCACATCCCTTGTAAGTTGGATTCCTAGGTATT TTATTCTCTTTGAAGCAATTGTGAATGGGAGTTCACTCATGATTTGGCTGTTTGTCTGTT ATTGGTGTATAGGAATGCTTGTGATTTTTGCACATTGATTTTGTATCCTGAGACTTTGCT GAAGTTGCTTATCCGCTTAAGGAGATTTTGGGCTGAGATGATGGGGTTTTCTAAATATAC AATCATGTCATCTACAAACAGGGACAATTATAGAAGGACTGGGGGTCCTTCTATAAGCAT TTCTAATAGAGGGTCCTGCCTTGCCGCTCTTTTGGCTTCAATATCCGCTTGGCAGTTCCT TTCTGTTTCCCTTTCCTTTCTGGTGACTCTGGCAGTGTAAGACTGCCACCTCTTTAGGTT TCTGTACAGCCAATAGTAATCTCCTAATGGCTTCCTGATGTTTGATAGGTGTTCCCTCGG AAGTTAGGAATTCCCCTCTCTCCATATTGCTGCATGGGCATGGAGGACTAGGTAAGCGTA CTTAGAGTCTGTATATATATTTACCCTTTTCCCTTCTCCTAATTCTAGTGCCCGAGTGAG GGCTATTAGTTCTGCATGCTGAGCACTAGTTCCTGGAGTGAGGGGATTAGTTTCAAGTAT TCCATTATCACTGACCACTGCATACCCCGCTTTTCAAAGTCCTTTTTCTGCAAAGGAACT TCCATCAGTATACAAGTTGAGGTTGGGATCAGTCAAGGGAACCCCTAAAAGGTCCCCTTG AGCAGCATTAGGTTTGAGCAATCACATGTTGGCATTTATGTTCTATCTTTTCTTCATTGT CTGGAAGAAATGTGGCTGTGTTAAGAGTTGCACAAGTGCGCAGTCACACCACTGGCCCAT CAAGTAATAGAGCCTGATATTTAAGTAAACGGTTGTCTGACAGCCACAAGTCTCCTTTAG CAGTGAGTATGCCATTCACATCATGAGATGTTCACACAGTAAGATCTCTTCCCTGTATTA CTTTAACTGCTTCAGATACTAAGACTGCTACTGTTGCCACTACCCGTAAACAATGAGGCC AACCCTTTGCCAGTACATCAATTTCCTTACTCAGGTATGCCACAGGTTGCAAGCTGGTCC CTCGGACCTGTATAAGGACTCCTAGAGCTATTCCTGTTTCTTTTGCGACATATAAAGAAA AGTCTTGCCCCATTGGCAAGCTTACCACTGGGGCTTGGGTTAGGGCCTTCTTTAGGGCCT GAAAAGCCACTTCTGCTTCAGGTGTCCATCTTACTAAATGGGTATTGGCTTTCTGAGTTT CCTTAGTGTGTATAATGGCCTGACTATTTCGCTGTACCTGGGAATCCATATTCGGCAGAA GCTTGTTATGCCAAGGAACCCTCTTAGTTGCTTTAGGGTTTTGGGATGAGGATAAGCCAG TATAGGCTGGATACGTTCCTCACTGAGGGCCCTTGTGCCTTTGGATAATTTTAGCCCTAA GTTTTTAACCTGCTGTGAGCAGAGCTGAGCATTTTGTTTGGAAACCTTGTAGCCACAGGT AGCAAGGAAATTTAAGAGTGCTTGGGTGGCTTGATGGCACCAGGTTTCTGATCGGGTGGC TAAAATTAAATCATCCCCGTACTGAAGGACAAGAGTGTCCAGGTATGAGAATTGGCTCAA GTCTTGGGCTAATGCCTGGCCAAATAGATGGGCGCTATGCTTGAACCCTTGGGGTAAAAC AGTCCAGGTGAGTTGAGACATTGGGTTCAAAGGATCTTCAAAGGCAAACAAGAATTGAGA GTCAGGGTGTACAGGGATGCAGAAAAAGGCATCCTTAAGGTCCAGGACTGTAAACCACTC TGCTTTCTGTGGTTTTTGGGAAAGCAGAGTACAAGGGTTAGGTATAGCAGGGTATAGAGG AAGAACAGCCTCATTGATAATCCTGAGATCTTGCACTAACCTCCACTGTCCATTAGGTTT CTGTACTCCTAAAACTGGAGTATTGCAGGGGCTATTGCATGGTTTTACTAGGCCTTGGGC TTTTAAGTCCTTAACAATCTTTTGGAGTCCTTGTTGGGCCTCAGGTCTAAGGGTACTGCC TTTGGTAGGGAAAGGAGGTAGAATCCTTTAATTTAACTTGAATAGGACAGGCATTCTTTG CTCATCCATATTGTCCTTCTGTTGCCCAGACGTCAGGATTAATTCCTTCCTCAAGCAGGG GAAAACAAACAGGTGTTCCTTCTCCTATGTTCAGATATATAATGGCCCCTGCTTTTGCTA GAATGTCTCCCCCTAACAAGGGAGTGGGGCTTTCAGGCATAATTAGAAAAGCATGTGAAA AGAGTAAAGTTCCCCAGTCACAACTTAGTGGCTGTCCTAGGACCCCTCGGATAGTGACAG ATCTGGAGGACAGTTGTCTGGGACAGGAGAGTAAGACTGAGAAGGCCATGCCAGTGTCCA GGAGACAGTTAACCTCCTGGCCTTCAATGTTCAAGCATACCCGGGGCCCTGTGAGGGTGA TGGCATGGGCTGGTGCTTGCCCCGGGCACCCTCAGTCCTGCTGCTGGATCATCTGGTTAG TGGCTTCTGACTCAGAGGACCTTCGTCCCCTGGGGCAATGGGCCTTCCAGTGATTCCCTT GACATAAGGGGCATGGACGAGGGGGCAGCTTACTTCTACTTGGACAATCTTTTTTAAAGT GTCCTTGTAGACCACACTGGAAGCAAGCCATATTAGGCATTCGATTTGCCCAGCTTTTCC CTTTTCCAGAGACTCCAAAGTCCGCTTGCCTGAGGGCCATGACTAAAGCAGTGGCCTTTT TTTTTATCCCGTTTGTCCCATTCCGCCTGCTTCTCCTGATCTGTATTATAAAAAACCGAG GTTGCCAAGTTCAATAGGGTCTAAGTTTTGCTCTGGGCCTAAGGCGGACTTTTGAAGTTT TTTTCTAATGTCTGCAGTTGACTGAGTGATAAACTTATCCTTTAAGATTAGTTGGCCTTC AATAGAGTCAGGTGACAGAGAGGTATGCTTCCTCAATGCCTCCCTTAGTCTCACCAGAAA GGCAGTAGGATTTTCTTCCTTTCCCTGTGTTATAGTGGACATCATTGCATAATTCATAGG CTTCTTCCTAGTTTTCCTTAGTCCTAGCACACAAGTTAGCAAATGTCTGCGGCACCAATT TCCATGTTCTGATTCTGTGTCCCAATGAGGGTCTACACTGGGAACTGCCTGCTGGCCTGT GGGGAATTGTTCTCTTTCCTCTGTTGTCATCCTATCATTGACCTGACTGAGATACCAGAG ATCACCAAACTCTTCGGGCTGCAGTTATGGCGACACTTCTCTCATTTGGGGTTAGTGTCT GATTTAGCAGTAACATTATATCTCTCCACATCAGATCAAAAGATTGTCCTAACCCTTATA AAACTTCAGTATAGCCATCAGGGTTATCTGAGAATTTACCTAGGTCTATTTTAATTTGCT TTAAGTCTGAGAGAGAAAAAGGTACATGCACTCTGGCTGGGCCGAATTCTGCTCCTCACA TTGCTTGGAGGGGGCATAATCGGGGAATATTGGCACTGTTTGGTTCATTGTTTATCCCTT TGTCTATCTTCTTTGGACCTTTGGGTAAAAGGGGGGTCCCTTATTAGTTGCAGAAGGAGT CGGGGGGATGCTGAGATAGGGAGGCAGACTCTGAGGGCTTCCTGTAGGGCATAAACCACA CTTTTTACATAATTGCGAGTTGTCTCTTAATGAAAAGGAAGTTTGCACATATGGCACTTC ACTCCATTTGCCCTCCTTTCTACAGAAGAGGTCAAGCTGTAAGATGGTGTTATAATTTAT ACTTCCCTCAAGAGGCCAGGTTTCTCCCCCTTGAAGAGGATATCATGGCCAGGCAGTACT GCAGAAGAATATAAGTCATTTCTTTCTTAGCGTCTGAGGGTCAAATTGGTCCTTATTCTC CAGAATACATCTTAAGGGCGTTTTTGCCTTGGGGTGTGGGGAACGTTTCCGATCTGAAAA AAGAACATAGGGATGCCAGCACCCCTAGTCATTTTCCGATGAGCATTAGTCCTAAAGCAT CCTCTAAGGGCCTAATGCTTATTCTTTTCCAGGGTGCGTAACCACCCATGGACCTCTGCT TATCGGATTAGTTACGCTCACCAATGTAGCAGTCCTGCACCTATTTTTCCACCTCTCTTG ACCACAAAGAAAGGGGTCTGGGCTGCTGGATTCTAGTGGTCCTTTACCAGCGTGCCCGAC ATTGCTTTTGCGCTCAGGGGTGAGTCCTAGAGCTGGGCTGGGTTCCTGGGTATTTCATAA CAACCCAGCTGCCCCATCAAGATGCATTCCCATAAACAACACTCTTATGCAAATTCGTTT CAGAGAGGTGTAGCGAACCTTTTGAGTCAGGATTGAAATAGTCTTTTGATTATGTAAGTA TGGGCTTGGCTGAGTGCAAACAGCTCGCACGTTTGAGGAGACCAATTATTAGGCAATTTT TCTAACTCTGCTTCCACAGAGTCTCTGTATTAATTACTGAATACCTATTGTGGTTTTTTC CCTCAATCACCTGGGAGGAACCATCTATCGTCCTGTCCTGAAGGGAGTTCCTCCTAGGTC TGGTCGGACCTTTGTATGGTAATTAAGATTTAAATCCTTTGTTAGGAAATCTGCTGGGTT AAGTGAATTATCAGTGGTTGGAGTTACATTACCCTTTTCTAACATAATAGCCCCATACTT TAAGATTTTTGATTTAGTAAGCTACCTTTTTGCTTTTTTTTTAACTTAGAATAATGTAAC TGGTGAGGTGTGCTCACAAGAAGGTTTCCTCTAAAAGTTACTTTTCTACTTTTAGCAAAG CAGTTGCCGCTACCGACTGAATGCATTTGGCCCATCCGCGGGTTACTGGGTTAAGGATTT TTTATAGGAAAGCTACAGGTTGCCAGTGGCCTCAGTGCTTTTGGGCTACGCCCTTATTTA CATTGACAACAGTGGTATTGGAGTATTATAGAGTCATAGAGAAGACCTTCAATTATCAAT TACAGGTTTTAAATTTACGCTGGCTTTTAAAGGAATAGGGCACACTTTTTTTTTTTATTC TATCTTTTTCTTTCTTTTTCTCTTTGACTCTGTCTTTGTCTCTCTCTCCGTCTCTCCCTC TCTCTCCGTCTCTCTCTCTCTCAGCCATTACAAACTTGGGGCCCTGGCAAGGGTAGTGGG GAACGGGTCCCACATAACTGCCCATGTCGAGAGCTGCATACCTGAATCAGGAGGGACACC AGGGATAAGACTCCCTGGGTTACAGCCCAGGTGCCTAAGGACACAACGCAGAGCCTCCCT AGATCCCTTTGGAGATACAACTTGCTAGAGGAAATGAAAGTGTGAACCATTAGTACCTAG GAGGCAGGGATCAGAGGAAGTAGATTCAAAGGTAAGGAGAATTTTGGGGCTACACTTTCA AGAAAGTCGTGGTCAGGACCCATGAGGTATGGGTCAGAAGGAAAGGTAGGGGCGCACCCA TGGGCGACTGTTGAGTAGAGACTTCTGGCTGCGCCATGATCTCAACAGGCTAATGCCGGG AGTTCTGGACGACAGCTTTCTGCCTCTAGTCAGCCCTCGGATTCCCCAAGAAAATTGAAA GTGGAAGCTGGCTCCAAGCAGACCAACGTCCCCAACCCAGAAGGGTTGGGGGTTGTTAGA AAGCCCTTCCGCAGATAGCGTAACACCTGAGTCTTAAGTCCGGCGGCCACGCTAATCGTT TTTAACTGGCTGACAGGTGCCCAGTATTTTCCTCCAATTCTAAGGAAGGATAGGACAGAA TAACAAGCGAAAGTGGTCCAATATTACTCACCGCTTTGGATGTCCCTTCGTGGTCACCAA AATGTTACCGGGGGTCCTTGCTTCCAGAGCTCCCAAGATGGTTGTGGGCCACTTCCACAA TGGTGGCAGGCCACTTCCAAGATGGTGGCAAGCCTCGTGTTCTCTTACCTGGGGTTCTTG GCCTCACGGATTCCAAGGAATGGAATCTTGGGCCATGCGGTGAGTGTTATAGCTCTATTA GAAGACATGGGTCACGGAAGAGAACCGTGGAACCCAGTGACTAGTGTTCAGCTTGATTAG GATGAACCCAGGCACTTAGCTGTGCAGGAACAATGGCAAGCCTTTAGCCTGATTGGGAGT GGCAATGGACACCTCGCTGGATCAGGAGCACAGCGGACACCCTGCTGGATCCGGAGGGAT GGGAGTCAGTGGTGGGTCTGCAGTGGCAGGTCTGCGGTGGCGGGTCTGCGATGGCGGCAA ACAGCAGTGGTGGATGGCGAGCGAAAGCTCAGCTCGAGCCATAACAAACATGGACCAGAA GAGTGCAGTTACAAGATTTAATAGAGTGAAATAGAGTGAAAACAGAGCTCCCACACAAAG AGAGGGGACCCAAAGAGGGTTGCTGTTGCCAGCTTGAACGCCTGGGTTTGTATCCCGATC CTTGTCCCTCCCACTGTGCTCTCAGGCAATAGATGATTGGCTATTTCTTTGCCTCCTGTT TTTGCCTAATTAGCATTTTAGTGAGCTCTCTGATTGGTTGGGTGTGAGCTAAGTTGCAAG CCCCGTGTTTAAAGGTGGATGCGGTCACCTTCCCAGCTAGGCTTAGGGATTCTTAGTTGG CCTAGGAAATCCAGCTAGTCCTGTCTGTCAGTTTGAGCCATAAAGTTAGCTCATGCTGGT ACCAAGCACTGATAGGAGATTTGTCAAAGGTCAGGGGCACCTCCACTCAGATCCCTTTAT GGTTACCAAATGTGAACCCCAAAAATTTGAGACAGGTCTCAGTTAATTTAGAAAGTTTAT TTTGCAGTTGGGCCCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAG GCAGATCATCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCT CTACCAAAATACAAAAATTAGCCAGGTGTGGTGGCAAATGCCTGTAATCCCAGCTACTCA GGAGGCTGAAACATGAAAATCGCTTGCACCAAGAGGCGGAGTTTGCAGTGAGCCGAGATT GTGCTGCTGCGCTCCAGCCTGGGTGGACAGAGTGAGACTGTCTCTCTCAAAAAAAAAATT AAGTTTATTTTGCCAAGGTTGGTTCTGATGACGTGCCCAAGGTGGTCAGATCACAGCTTG GTTTTATACATTTTAGGAGACATGAAACATCAGTCAATATATATAAAATGAACATTGGTT CGGTCTGGAAAGGTAGGACAACTCGAAGTAGGGAGGGGGCTTCCAGGTCACAGGTAGGTG GGAGACCAACTGCTGCATTCTTTTGAGTTTCTAATTAGCCTTTCTAAAGGAAGCAATCAG ATACGCGTTTATCTCAGTGAGCAGAGGGATGACTTTGAATAGAATGGGAGGCAGGTTTGC CCTAAGCAGTTCCCAGCTTGAATTTTCCTTGTAGCTTAGTGATTTTGGGGCCCAAGATAT TTTCTTTCACAGCGTGAAAAACAAAAGCCCTTGGTATTGTCAGCTTCTTGAGTTAGTTAA CCTAAGAACGTTTAGGGGGTTTCATAAATGTTTTAATGCATGCATGTCTGTTTTTCTGAT TAAGATAGAATACTGGGAAATTTGGAAGTGGAGTTTAAACACAGAATCAGCTGCAGTCAT GTATAGGTCCCCTCCTGAAACACAACTCTCAGGCTGTGTTGTAACAACGTATATAATAAC TGTCCCTAACTATCTCTCAGGGCTTTTGTGAAAAATAGAGGAAATAATACTTAGACAAAT ACATTTAATGTTTTCAAATGGCAAATGGCATAAAATCCAAGGGCATACTATTTGATAGTA ACTCTTTGAAAGATAAGTTATCCAGAAAAGGATGTATTGGCCTAAGGGGATCTTTGAATT CCTTAAAAATCTGTAGTCATTTTCCTTGGTAAGCTTTCAACAACTTCATGAGTGTGTATC TTCTTGTGATAATCTTGCCATGGGTTGGATTGCCTTTGAGTATCCGGTTAAAATCCTCAT ACCTTGAACAGACACACTGGAATAGTCATAAACTACATCCTTGCCTAAGTTGGCAGTGAT GGTAACTTGCCTTCCAAGAAGACTGATATGCCCGTTGAACCAGAAGTTGCAGTACGGCTG AAGTGTCCAGATTAGTGCTAACTGGTGGAAATACAATGTAAGCTACAATGTGAGTGATAT CTGTAGTTATAAATTGTAAAATAGCCACGTTTTAAAAAGTGAAAAGAAATAGGTGAAATT AATTTTAGTAATACAGGTAACAGTATATAAAAAGTGTTAATCAGGCAGACATGGTCTCAT GCCTATAATCCCAGTGCTTTGGGAGGCCCAGGTGGGAAGGTTACTTGAGGCTAGGAGTTT GAGACTAGCCTGGGCAACATAGCAAGACCCCTTCTCTACAAAAAATTAAAAATTTTCCAG GCATGATAGTGCGTAGATGTGGTCTCCTCTTCTCTGAAGGCTGAGGCAAGAGGATCCCTT GAGCCCAGGATTTCAAGGCTGCAGTGAGCTATGATTGTACCACTGCACTCCAGCCTGGTG ACAAAGTGAGACCCTGTCTCTAAAAAAAATTTTTTTTTAATTTTTTTGAGTCTTAAATCT TTCCATACTTAATTTTTGAAATCCAGTGTGAATTTTATACTTACAGTACGTCTGAGTTCA GACTAGCCACATTGCAAGTGCTCAGTACTGACGTGGCTACTGGCTGTTGAACTGTACAGA TTGATACCATTGTAGGTACTTTGTATTTGCTAATTTGATCTAAAAGAGGTTTTGTGGCTG TTTATGTTTTGTATAGGCAGAGTTGCTAGGGATAAAGTATGTATTTATGCATAGTAATTC ATAAATCTAGTTGTAGACATGGTCTCTTTCCTTTTACTGTACTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTGATACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCA ATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCC CGAGTAGCTGGGACTACAGGCGCCTGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGT AGAGACAGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCAC ACGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCACCGCGCCCGGCCCTTTT ACTGTACTTTTTAAGGTAATATTAACTACACAAGCTGTTCTCAGTTGGAGGTGATTTTGC TCCCCGAGGGACATTGGCAAAGTCTGGAGACATTTTTGAGGGACACTACTGGCATCTAAT GGATAGAGACCAGAAGTGGTGCTAAATATCTTACAGTGTACAAATCTGTGCCCTATTCCC CCACAACAAAAAAGTATGCAGTCCAAATGTTCATAGTGCTAAAGTGAAAAGCATTGACTT AGAACAAAGATTAACAGTCAGGCTGAGTACCATAGCGCACACTTGTAATCCCAGCACTTT GGGAGGCCTAGGTGGGAGAATTGCTTGAGGGCAGGAGTTCAAGACCACCCTGGCTAACAT AGGGTGTTAGACTCAATCTCAATTTAAAAAAAGGAAAAAAAAAAAGGTTAACCGTCAGAC TAAATGTCCTGCTCTTGATATAAAGATCACTTTTAAATTTGTCAACAAACTAAGTACTGT GGGACTATAAAGAAATACTAACCATAGTTCTTGGCCTCTAGGAATTTATAACCTAGGAAT GGAAAGTGTATTGCAAGGAAGAGTCCCATCAGAGGTACTGTTTAGAAAAGGAGTTTCATG AGTAAGTTCAGGAAACACTGATGTATCCTTTTTTAAAAATTTTGGTAAAATACACATAAC ATAAAATTTAATACCTGTGTTAGTCCATTTGCGTTGCTATAAAGGAATACCTGAGACTGG GTAATTTATAAAGAAAAGAGGATTATTTTGACTCACAGTTCTGCAGGCTGTACAAGAAGT GGGGTGCTTGCTTCTGGTGAGGGCTCAGGAAGCTTACAATCATGTCTGAAAGCAAAGTGC AAGCAGGTGCGTCAAATGGCAAGAGAGAGGGAGTGCCACACTCTTTTTTTTCTTTTCTTT TCTATTTTATTTTATTCTATTCTTTTTTCTTTTCTTTCCTTCCTTCCTTTCTTTCTTTTC TTCCTCTCCTTTCTTTCTCTTTCACTCTTTCTCTCTTTCTTCTCTCTCTTTCTCTCTCTC TCTTTTCTGTCTTCTCTTCTCTTCTTCTTTTCTTTTCTTTTCTTTTTTCTTACAGGATCT TACCCTGTCACCCAGGCTAGAGTACAGTGGCACATTCACAGCTCACTGCAGCCTCAACCT CCTGGGCTCAAGCAATCCTCCTTGTCTCAGCCTCCCATGTAGCTGGGACCACAGGGGCGT GCCACCATCTCCAGCTAATTTTTAAAATTTTTTGTAAAAACAGGCCTCACTTTGTTGCCT AGGCTGCTACACTCTTTTAAACAATCAGATCTTGCATGAGCAAGAGGGGCACCAAACCAT TCGTGAGAAATCTATCCCCATTACCCAAACACCTCTCACTAGGCCCTACCTCAGCATTAG GGATCACATTTCAACAGGAGATTCGGAGGAGACACACACCATCTTAACCATTTCTAAGTG TACAGTTTTGTAATATTAATTACATCCTCATTGTTTTGCAATGATTACCACTATCCATCT ACGGAAGTCTTTCCATCTTGCAAAACTGGAACTACGACCCATTAAACAATAACTCTCCAT TTCTCCTTGCCCCCAGCTCTGGCTACCACCATTCTACTTTCTGTCTCTATGAACTGACTA CTCTAGGTACTTCATATAAGTGGATATGTTGTATCCCTTTTACATATTAAAACTTTTGAG TAGTTCTGCAGTAAATAAATATGCTTAACATTATCGTGTTTAAGTTAGTTGCCATTGAAA CTTTTCTCCCACAGTAACACGTGGAGGAACATACGTTGGGAATATCAACTGACACGCACT GTGCTAGGATCTAGAAATACCATGTGGACTCCAACACACATAGAAATAAGGAAGTGGAAT TCCAAAGGAAGGCAAAGTGTAAAGTCATCTTTATGGAAATGAGTGATGAAGGTGAATACC TGAATGAGATGTCAAGAGGAGGAACACACTGGAGAGAAGCAGTAAAGATTTAGGACTGAA CCTTAAAGACATACAGGCTTGAGAGAAAGAAAGCATGTAAAGAAGACAGAAATGGTTAGA AAGGTAAGAATAGAATTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTTTATTG CCCAGGCTGGAGTACAATGGTACGATCTTGGCTCAACTGCAACCTCTGCCTCCCAGGTTC AAGTATTTCTCCTGCTTCAGCCTCCAGAGCAGCTGGGATTACAGGCACGCGCCACCATGC CTGGCTAATTTGTGTATTTTTAGCAGAGATGGGGGTTTCACCGTATTGGCGAGGCTGGTC TCAAACTCCTGACCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAAGTGCTAGGATTACAG GTGTGAGCCACCGCACCCAGCCAGAAGAATAGATCTTATACTTACTATTAATAGAAAAAC TTATAGATTTTGGACTGACTACAAAAGGGCAGTGATATTCAAAATTGATCAACATGATAC ACAAATAGATATTTTCAAGTTCATTGGTCATTAAAACTGTCTTATGTATAAGCAATACAC AAGACAAAATAAGGCATTTTTTTTTCAAAGATCTATGCACAAAAAAATTTGTTGCAGCAT TATTTGTGATATCAAAAGTGGGAAATAGCTGGGCATGGTGGCTCATGCCTGTAATCCCAA CACTTTAGGAGGTGAAGGCAGTAGGATAGCTTGAGCCCAGGAGTTTGAGACCAGCCTAGG CAACAAAATGAGATCCCATCTCTACAAAAAAATAAAAAAATTAACCAGGTGTGGTGGTGT GTGCCTGTGGCCCCAGCTGTGCAGGAGGCTAAGGTGAGAGGAACCCTTGAGCCCAGGAGG TCGAGGCTGCAGTGAGCTATGATCATGCCACTGCACTCCAGCCTGGACAACAAAGTGAGA CCCTGTCTCAAAAAAAAAAAAAAAAAAAATTGTGTGAGGGGAAATAACCTAAATGTCCAA CCATGGGAGAATTAGTAAAAGAAATCACAGCAACTGCATGTGACTGAGTCCTGTGTTACT ATAAGTCACATCTTAAAAATGACTTACTAACAGGAGCATGTCATTAAATGATGTGCACCT TAAAAACTTAGAAATTTCAATTGTTTATTTTTAAAAACATCTACATAGCACTATGTGTCA GGCACTATGCACTTTGTTCATCTGAACTCATCTTTTTATGGCGAGAGATACAATAAAAGT CAAAATACAACGGTCTGGAATTTCACCATATGAATTGGTGTTAAAATCTGATAGGTAAAA AGAACTGTAGAGACAGACTGTAATAGGTAAGTAGGCACAAAAGACATAAATAGGCTGTTC ACAGAAAAAAGGCAATAAACATTAAAGGATGCTTAAAAGCACTGTGAGTCTGGCTAATGC AAATTAAAACCATGAGATACTATGTTTTGCTTGTCAGAGTGTAAAAATTAAGGTAATATG CATCTTTGAACCTAGGAGGTGGAGGCTACAGTGAGCTGAGATTGTGCCACTGCACTCCAG CCTGGGCAACGAGAAAAAGACTCCGTCTCAAAAAAAAAACAAACTTTAAAATATATACTC TTAATACCCAGCTATCTAATTTTGTCAGTCTGTCATATACAAATAAAGCATCTTTGTGAT GGTAAAAAAAATATAGAAATAACACATTTTAAGAAATAGTTTGATAAATTGTAGTATATT CATAGTAGGGAATACCACACAGCTATTGAAAGAGATCTATATACATTGGGCTGGAGGCTG CGCATGGTGGCGTGCCTTCTCCTTTTGGGTCACTTAAGCCCAGGAGTTTGAGTCCAGCCT GGGCAAAATAGAGAGACCCCATCTCTAAAAAAATTAAAAATAAATAAATTGAGCTAGAGA AATGACTGTGATACATTGGGAAGAGAAAAATGAAAGCTGCCAAGTAATGTATATAATATG ATCCCATTTTTGTAATTGAATAAAAGGCAAGAAAAACACCCTTTAAGAAAATTTTGTATA CCCTGTGTATATATGAGTAAGCCTAGGGAATGGTATAGAATGATATTCAGCACCGAAAGA GTAGTAGGTAGGAAATTGTACTTCTATGCTGCTTTATATATGTAAAATGAATGTTTTTAT TTTTATAATTAAAAATCTAATAAAAACAGTAAGTTAGATGGCGCAGAGATAGGATTGAAG GAATCAGCATACAATTAGTGAAGTAATGAACTCAAGAGTTATTCATATTTTAGAGGAAAG GAATGTGGCATAAACTCACAGCAAATATAAGTATTTTATAAAATTAATTAATTTTAGCAG TAGTGAATGGATGACCAATTTCAAGAGAAATGATGAATACATTTTCTCTGCCATGGAACA TAGTCAAGATTTAGTTCTTTCTATGTAGATCCTCTGAGCTACTGCTGAATTAAAAACAGC ACTAAGAAAAAACTGTAGTTTTTACTTGGCCATCCTAGGAGTTCCAGGACTTTGTAGCAT ACAAAGTGAACAGAGATGATTTAAACTTCTTTGTGCCTGTTTTGTTTTGTATGACTAATG GGCTGTTCCCCTGGCCTTGATTTGCCAGATTTGCATTCCTTCAGAGCATCATCCCCTCCT GGGAACTACCGTACTAGATTCCAAACTGAAGCTCAATTGCAAAAATTCTACACAATTTGC GCTTTCCCTCTTTAAAGGAGAACTGGAAGTGTGAACAAGCATTTCCCAAATCCTCAATCT ATGGAAGACAGGATAAGAAAGGCTCCTTCCCTGTCAGCCCCCTTTTCCCAGGTTCAAGGC AGTAGAGAACCTGTGTATCAGAGAAGTCTTGCCAATAAGATCCATGTGATAGAGGCCTTC AGAGCACCCACCTTTATAGGCATTCCAGAATGATTCAATAAAATCTGCCACTTACCAGCC TTTGGGGAAGAAAAATATAGTGATTTCTTTTTTAATCATTAAACTTTGTTTTAGTGGGAT AGTAATTGTTTTTATTCTTTTGTAGCATATCTGTCACCACCACCACTATCTCAGTGAACA AAAAGAGTGTTACTTAAGCTTAGCTAACTAACCTTCAGGGAATATTTAATTTAATTCCTG TTTGCTCTTCCCTAGGGCTTTGTTTTGCTTCCCATGGCATTAGTTTGCCAACTCTTGTTA TTTTTGGCCTTCTCTTATAACCCTTGCTGTTTTGTACACTCCCTGAGGATTAGGGCAACA TCGTACTCACCTTTGGATCCTCTACCCTTGCCCCATTTGCCTGCCATTTTCACTTATCCT TCAAAGTCCTTTGCAGGTGACACCTGCTATCTCTGAGAAGGCTTCCCTGGCAGCCCCAAA TGTCTTCCTCTGATCTACTTCTACACCTTGACTAACTTTTGTTATAGAACTTTCTGTATA TTATTGAAAATATCTGCTGATTTGTTTGTCTTCCCTCTATACTTTTTCCTTGGGAGCCAA GTCCATATGCTTAATAACCATTTGTCAAAGGGAACTTTAGTGCCTAGTGGAAGGTGCCCA GTTGAATGCCTTTTACATAGAAGATTCTCCCCATAGTTTGTTCAGTTAGTTGCTGAAGCC ACTAAATATTGGGCATATTGTTATAGAATGCTCCTTGTTGACCTTCAGGTTTCAGTGTAT TCATTCACTCAACAAATATTTGAGTGCCTACTATGTGCCTACACCCTTACTGAGCCAGAG ACATACATTCCTTTAGGAATGTATTTAGCTACTAAAACATTCCTAGTCTAGGTACTGGAG ATACATCAGTGAACACAACTGACAAAAACGCCTGCACGCAATGGAAGTTCTATTTTAGTG GAGCAAATCAAACACTAAACAAAATAGGTAAAGAGAATATATAGTATGTTAGATGGTGAT AATTGCTATAAAGGAAAATAAAGGTGGAAGATAGAGAGTATTGGTGCAGGAGAACTTAAA TCCACCCCCCACCCTGCCCCAAGATGTGTATTCCTGTAAGTTCTTTTTTTAAGAATTCAA TTTTAAATCTTATCTGGAAAGATATCACTGAAACAGTGACGTTTCAATAAAGACCTGAGA AAGTCATGAATACTGAAGGAGGAGAGTGTTCCAGGAAGGGGAACAGAAGGTGTAAAGGCC CTCAGACTTTCCATTGCTGTGCTTTCCATTGTTTGAGGGCCCCATTAGAGAGGGTTTTAA GCAGATGAGTAACATAATTTGACTTCTACAGCTGCTCTTTGACTTACGATGAGGTCGCAT TGGGATAAGCCCATCATAAATTGAGATACTTTCAACTTAACAATAGTTTCATCTGAACAT AAAGTCAAGGATCATGCTGAAGGCATATCACTTTTGCACTGTTGTTTTCTGTCAAGCAGT CTATATTTTCAAAGGAGCATTCTTGTAGCTACTATTGAGACTAAACATGGGGATGGTGGC AAGGGCAGAAATAGGGAGATAAATTGGAAGTCAGTTGCAACAGCTCAGGAGAGAAATATA TCCTATATCCTTCTGAGTGAGTCCAGTATCAAGTCTGGTCTTTGAACGACTAGTTAACTC TAAGACTTAAGAGCCAGCAAAGGAGACTGGGGAGTGGCTGGGAGAGTAGGAGGAAAACCA GGAGGAGGTGGTGTCATGGGAGTTAAGGGAAGGCTAGGAAAAGTTCACGACGTCACCAAA TGCTGAGAGGTCACTTAAGGGAAAGAGAGGCTGCCAAGGGTCCTTTGAGTTTTGTAGTTA GGTCATAGTTGACCTCGGCAATAGAAATAATTTTAAGAAAATTCATGCCAAACTATACAA ACCAAAGTTTCTGTTTGATAATAGTTTTTATAATAAGGATGCAAATTAAAGTGGTGTTGT TTTGGGGACAGGGTCTCACTCTGTCAGCCAAGCTGTAGTGCAGTGGCACGATCACAGCTT ACTGTAACCTTGACCTCTTGGGCTCAAGCGATCCTCCCCACCCCAGCTTCCCTCGGAGCT GGGACTGCAGGCACATGCCACCATGCCTGGCTAATTTTAAAAAATTTTTCTAGAGTTGGG GTCTTGCTGTGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCAATCCTCCCACCTC AGTCTCCCAAAATTAAAATGTTTTGATCACCTGTGATATACCAGGCCTTGTCCTAATTTG AATTTTAATCTTAATTTTTACAAAACCCTATAAGGGCAGTACAGTACATTATCTCTATCA ATGGGGAAACCTCAGTTCAGGGTCTTGCCTAAGTCTGCTTCCAGAGCCAGTACTCTCAAC CATTAAGCGGAAGCCACCTGTGTAATGAAGCTACTGAAACATACATTATAAAGCAGAAAT GCTGGACTGATAACAGCAATATGGTTGAACCATGGTACTTTTATAGCATCTACCTTTCTA GAGCCCCTTGAACATAAATGTCATCTGTGTTTGTTGCTGTTGCTACCCCATCACACTGCC ACATCCTGTCTTTTTACCTCCTTTCCTGCTTATATGAAGGTGCATTCATACACTGTCCTT AGACACACCTCCTGTCATCTGCAGTGTCACACACAAAGTTAGCAACATCCATGGTCAGGG AAAATTGCTTGAAAACAGCCTTATTCACAAATATACACATACAAAATTGTCATCCATTAA GATTGTCTGTTTTTCTTTGTGCTTCTGTAGACAGTCTTCTTTTGGGGGTGGCTCACGTGT TTATGTACACAGATTTTCTCATACCATATGTCACACTCCTGTGCTTGAGGCCCATTACAG ACACCCTTACTGAGCCAGAGACATACATTCCTTTATCTGTTTAGCAGAGGCAGTGGAGGC AGTGGTGGTGAGCTGCATAGCAGCCAGCAGCAGTTACAGTGATGGCAGTGGCTTGTTTAT CCCACTGCTCAGCAGAATGCAACCCTTTTAAAAAAAGACCAGAATGATCTGAGATGCCAA GGCTTAAAGAGAATTCTTGGTTCTCAGCTTCATAAAGGACCATCTCAGTGATGAATAACA GCATCTTCACTGCTGTTATTAGGCAGCCCTTCTCCCTATCTATCTTTGCTGAAAAAGTGA GGAAAGGAGAGACTCTGTGTCATGTGGAGTGTCTCTTTGTGATGAATTGTATCTCAGATG GGAGAGGGAGGGTGAGGGGCTATGGCAACCTGAGTCTTTTTTTTTTTTTTTGAGACGGAG TCTCACTCTGTCGCCTAGGCTGGAGTGCAGTGGTGCGAACTCGGCTAACCTCCACTTCCA CCTCCCAGGCTCAAGGGATTCTCCTGCCTCAGCCTCCCAAGTAGTTGGGATTATACGTGT GCCCCATCATGCTTGGCTGATTTTTGTATTTTTAGTAGATACAGGGTTTCACCATGTTGG CCAGGCTGGTCTTGAACTACTGACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAAGTGC TGGGATTACACAGACGAAGTTGCATAAACTCATATGAATGCATGAAGTGCAAGGAAGAGA CAGCACGATATAAGGCCATATATAAAAGGGACAGATTATTGTATATGTGTGTGTACATGT AAGAATTGTTATGATATACTGAGGAGCCCATTGTGGCAAATAGTGCTGAGCCATAAAAGT TCTTGCCAACCTACTGCAATTGTCCAACCTGCAGGATCCTGGGACTGAACACATCTGGAC AGTTCTCTGTATTGTTAGGCCATGGCAGGTAAATTTTTGACCCCTTGACATCATAAAAGC CTCCATACCATCTTCACCAAGACACCTAAGGAATCAGAACCCAGTTGTCTGTAGCAGTCC AGGTGATATTTGAGGGTAGGCTGTTTTGCATAATGGTTAAACCTGAGACATCCTAGTTAA ACTTTTCGACAGTTTCTCATCTGTAAAATGGAGACAATAGTATTCACTTCAAACATTGGC AGCACTGAGACAGCACATGTCAAATTGCTCAGCATGGTCTCTAACATGGAGTTAGCTATG TTGATATAACTGAATAAACAAGTGTGTGCCCTACAGCCCATCTTTACCAAGGCTGAGATG TTTTTTTCACAAGGTTCTCTCCCTACTCCCCTTCCTCATCAGAAAGAAGTTAGCTTTGCA TTGGCCTCTTCCCCAGCAAGACTACTTATTAGCTCTGGGAGGGTGGGCAGGACATTCCTT CATCATCTTCCGTTGGTTTAATTCTCTTATTTGACCTGAGGAGACAAGAATTGAGAACAT ATAAAGGCATTTATATTGCCATATCAGGCTGCCCAGTAAAAAATTCTCTCTATTCCAATG TAAATTTTAAAACAATTTTATTAGTATGTCCTTTGGCCTTTCAAGTTGGGGGGAAAAATC AAAACCAGTATTCTGTACTAGAAAAATCTAACTGACATTTGTCTTACATTTTGTCATCCC AGCCAAAGTTAGGTAATCAAATGGAACTTTAAGAACTAAGCTTTACTGAACAAACTGTGC CTTAAAATACACTTAAACTGAGGCGCGGTGGCTCATGCCTGTAATCCCAGCATTTTGGGA GGCCGAGGTGGGTGGATCACCTGAGGTCAAGAGTTCAAGACCAACCTGGCTAACATGGCA AAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCACGCACCTGTAGT CCCATCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGATGCAGAGGTCGCA GTGAGCCGAGATTACACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCAA AAAACAAAAACAAAAACAACACATTAAAACTACCTTTGCTGTCTACAAGCCGCTCGTATT TAGTTCTATTTCTTCAACTGCCTGGCTTTTTCCCTTATCTTCACCTGGATAACTCCTGCC TGTTCTTCAAGACTCAGATGTCGTTCTCCAGGAAGCCTTTCCTAATGTCTTTTCCCTGGA AATATACATTTTTAAAAGTTAGATATCTTTACTCCAAGAAACCTGTATTTATTCTGTCTA CAACAGTTTCTTCCTCTGCAGTTTTTGTACTTGTCTCTTCCTTTAGACACTGAACCCGCT AAGAGCAGGGATTAAACTTCATTCATTTTTTACATTGCCAATGCCTGCTATAAAGAATCA CATAAATGTGTGAATGAGGTTAAGTTTACACCTTATTCCTGCTCGGTGTGTATTATTTAG TTTATGAGGACATCTTGTGGCTAGATCATTTATTGCTATAAACAGACGATCATAGGCCAG GCGCGGTGGCTCACGACTCTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACCT GAGGTCAGGAGTTCGAGACCAGCATGGTGAAACCTCATCTCTCCTAAAAATACAAAAATT AGCTGGGTGTGGTGGCATGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGGGAGGA TTGCTTGAACCTGGAGGGCAGAGGTTGCAGTGAGCCGAGATCAAGCCACTGCACTCCAGC CTCAGCAACAGAAAAGGACTTCATCTCAAAACAAAAAACAAACAAAAAAACAAAAAACAA AAAACCCAACAACAAAAATCCTGTTCTAAAATTTATTTTTGACATTGATTTACCTGTTTT GCAAAACATGACATAATATTGTTTAGGATGTTTTATATCGCGTGGTTCTGTTTTCCTTCA GGGCCTTCAACAATAAAACCACTAAATAGGTGGTTTGTGAAACTCTCAAATGTCTTCCTG GTGGGAGTCATACCTAGAGGTTACTCATATATAGTTAGTGATTGGGAGATGTGAAGGTGG AAAGACCTACATCTACATCTCAGTTTCCATCACATCTTGGGTGATCTTGAAAATAAATCA CTCTGAATTTAAGTTCTCTGCAAAATGGATGTTGTCTCTTCCTTACTATATAGTATATGT AAAGTGCTTGGCACAGTGCCTAGCATATCAAAGTGCCTAATAAATGGTACTTATCTAGAA TATAACCAACCATTTAATGCTTGAGACATCCCCCTACTCCCAAACACAACAGACACACCA AATACTCATCCATATTCTTCCTGAACACCTCTAGTGAGGGTGGAAATTACTGTTTTGGAT GCAGCACATTCCACTCACAGCTCAGCTCTAACTTATACCATGATATTATACCCTGATGGT TTTTCCTAGTAATTTAAACACAAATATATAAGAAAACTTACCTTTCCATAAGTTGCCTTT TTAAAGATGTTTGATATAAAAATCATAAATTCTTTTTTTTTTTGAGACTGAGTCTCCCTC TGTCATCCAGGCTGGAGTGTAATGGCATGATCTCAGCTCACTGCAACCTCCACCTCCCGG GTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAGATTACAAGGGCACGCCACC ACACCCGGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTCACCATGTTGGTAAGGCTG GTCTCAAACTCCTGATCTCGTGATCCACCTGCCTCAGCCTCCCAAAATGCTGGGATTACA GGCGTGAGCCACCGTGCCCAGCCAAAAATCATAAAATTTTAAATGCATTGTTGCATATGT TTATCTTTCATGTAATACTTTTTCCTTATACTTACTATAAATGGGCCAAAACCTTAAAAG CAGTAACTTACTTTGCTGGATTTTATTGTTACATTTACACTTTATACTAACATGGGTTTA TAGTATAAAAGTTTTTTTTAAATGCTAGTAACTCAATGACTGAATTTGTCTTTTAAGTTG AACTGTTCATTAAGTGACTTAAAATGTTATTATTCTGCTTGTACAAAACTAGGAAACAAC AAATTAAACCTATAATGAGTTAACAGATCTCAGCTGGGTGGCTTTGTTGGCGTCAAAGTT CCAATGAGATAAATGCTAGTAACTCAATGACTGAATTTGTCTTTTAAATTGAACTGTTCA TTAAGTGACTTAAAATGTTATTATTATTCTGCTTGTACAAAACTAGGAAACAACAAATCA AACCTATAATGAGTTAACAGATCTCAGCTGGGTGGCTTTGTTGGCGTCGAAGTTCCAATG AGACATTAAAAAATGCCAGGCGTCATACATATGACTGAAAAGCTCAGACTGAATGTTTAA TTTCTGCAGAGGAGTGAAGATCAGCAAAAACTACTATTTTTTCACTAAACACTCCTTTTT CTTTAAAAATAACTTGCATAAGGGTTAATTTCTATCAGAGATTGGCAATTTACTTGAATT TCTGAGTCAACTTTTTTCAGAAGATTCAGTTCAATCCATTGTTCTTCATGGGCTTTTTTG GCTTTTCTAATTCTACAGAATTAATGTTCAGGATTCTTTTTTTTACACTTAGATTACTCT TGTCTCTGCTGCTCCTGGGAAAGTGATTTGTGAAATGAAAGTAGAAGAAGAGCATACCAA TGCAATAGGCACTCTCCACGGCGGTTTGACAGCCACGTTAGTAGATAACATATCAACAAT GGCTCTGCTATGCACGGAAAGGGGAGCACCCGGAGTCAGTGTCGATATGAACATAACGTA TGTATCCAAACTGTATTCCAAATCCCTTCTGTGTGATAACTGTCTAAACAACTGAGACTA AACACATTTATATTATTAGTAACGCATGAGATTCAATTAGCTGCTTATCTCCTTAACTGC ACCTATAGATTTTGTCCTAAAATATTCCAGCCTTAAAATCTAGAACTAGAGCAGTTAATT TGCAAGTACAGTGTGTATCAATAGTAAAAAGGGAATGATCCCAAACATTCAAAAGAGCAA CATTCAGCTTTTAATGTGTATACTGATGCAGGGGGAAAAATCACAAACTGATGGCTCATA ACTGTTTCATACAGTCCTTAAAAGTGCCATTCAGGGCCAGACGCAGTGGCTCACGCCTAT AATCCCAGCACTTTGGGAGGCCGAGGCAAGAGGATTGCTTGAAGCCTGGAGTTCAAGACC CCCATCTCTACAAAAAATAAATATTATTTAATTTTAAAAATACCACTTATAACACTATGA GGATTGTATTGAGTACATACAATTCAAAGTAAAGTTAGAGTTCATATACACATTATAATC TTACTCTAACAAACTGAACACCATTGCTGGGGTTTTTTTTTTTTTTTGGACACGGAGTCT CCCCATCACCCAGGCTGGAGTGCAGCGGCACAATCTGGCTCACTTCAGCCTCCGCCTCTG GGGCTCAAGTAATTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGTGTGCGCCA CCATGCTGGGCTAATTTTTGTGTTTTTAGTAAAGACGGGGTTTCACCATGTTGGCCAGGC TGGTCTTGAACTCCTGACCTCCAGTGTCCACCCACCTCAGCCTCCCAAAGTGTTGAGTTT TAAGAATGGGCAGCAATCCTGGATCTCTCCCTGTGACTACACAGACATGTTCTGTGAGTT AAACTACATGATCAGGGAACAGTGCCCCTCAGGGTCAAACTTCCAAAATGTAAGAAACTC AATTCCAACATAAACTGGTACTACTGCAGCCCCATTCAATAAAGAAAGAGCTGGGCACAG GGATTTAGTTTCAAGACAACTGCTTTTTCCACCTAAGCAACAAAAATGTAACTAACTGAG AGGTCAGGTTGAGAGAGCCATTGTGAGTAGATATGAGGGTAATGGAAATAATGTAGGCTT TTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTTTGTGGCCCAGGCTGGAGTGCAGTGGT GCAGTCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCC TCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCATGCCCGACTAATTTGTTTGTATTTT TAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGCTGGTCTCGATCTCCTCACCTTGTGAT CTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCA ATGTAGGCTTTTAAGGAATCTAAATATTTTATCAAGTTTACTTAAGAAACATTCAGTCCC TCTTCATGGGAATAACTTAAATTGAGGGTACAATAAGCAAATTACAAGATGCAGCCAAAT GCTCTTTTTGAAATTAAGATGTACAGAAAAGAAAGGCTCTGCTTATGTTACTGGTGTGCA TATTCAGCAGTCCTTATTTCATGTGGTAAGAGGTGAGATCAGTAGATGACTTGATTTTCC CTAAAAGTCTCTATTAAGAGCAGAGAGATCTTCAAACCTAGCACTGCATTTCATGATCTA CTAAGGTACTTTTGCCTTTAGAACCCTAAGGAATTTTCAGTAAGTCAAACATAGTTTTGG CCTTTCAAATATGTGTTGCCAAAAGCATTGGCCATCAAGAGCTGCCTACGCTTCAAAAAC TGATTCACTTCAACAAAAACTAGGACATGGTCTTTCAAAAGTTAGAGATATTTCAAAAGT AAATGAATAATGTTTCAGTCAGTTAACACTTCATGATTCACTCTTTGATTTACTTGACAT GGTACCAAATTTACTCCACCCCTGCACATCAAGTCCTATATTATACAGACTGAGGATGCC TGTTAGACTGTGACTTAGGTTAAAAACAAGCGAGGTTCCAAAACAACAAAAGGGGAAATT TTAGAGTATTACTGACAAAATGTCAATCTCCAAATTCCCCGGACTTAATGTTTACTCATC TGTAGCACAAAGGGTTCCTTATCTTCCCTCAGTTTAAGTTAATGGCTGTTAGCCAAAATT CTTGATTTCTAAGACAAAATTTAGGGAAATAATAAAAACTGGCCAAACTACTACTAAACA TACTATTTTTCATTTCTTTACATTGAGGTATGTGAATTAAAGACAAGCCTGTTCTTTCCA GCAATAAGATCCACCTTTTTTTTTTTTTTTTTTTTTTTTTTGTGAGATGGAATCTTGCTC TGTTGCCCAGGCTGGAGTCCAGTGGCGCGATCTCGGCTCACTGCAACCTCTGCCTCCTGG GTTCCTGCCATTCTTCTGCCTCAGCCTCAAAAGTAGCTGAGATTACAGGTGCCCACCACC ATGCCTAGCTAACTTCTGTATTTTTAGTTGAGACGGGGTTTCACCACGTTGGCCGGGCTG GTCTCGAACTCCTGCCCTCAGGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTA CAGGCTTGAGCCATCGTGCCCGGCCAGATCCACCTTTCTTATACCTCCTAGCCATAAATA CTGAAGTCTTATTTTGAATATGGCAAAAATACATATCCTTTTTAAAGGTTTCTTTCTAAA AAGCAGAAACATAAAAATAAACTGTAAGGAAATTATTTCCCTTTAAAACATTAACATTTG TTTTAAACAATCCTCATCTCCCCAATTTTTTTTTTAATTAGCTGGAGCCAGCTGAGTTAA AGACAACTTATGATTACAAGTGACTAGGATGTACATCTCTTAAAAATATAGACAGTCCAT CATCAAGATTGTAAGGACATCATATCAATTCCTTATAGTTGTTATATTGTCATTTTAGAG TCAAATAAATTGTAAATATGGATAGGACAATATACAGACACCAAGTGATATTTCATCTAA GAAGTTAAGGAGATTAAATGAAAGCTGGAGGAAATCTTTCACCAGCCCCAAATAAATGTG AAGTGGGAAATGTAAAGGGAAAAAAGGGGAGGCAAGAAAACCTCTTCTCACATATTTGGG AAAAGAAACTTGTGTGGGTAAGGAATGGGTAAAATAGAACCTGGTTAGGACCAGCCATTC ACATTTGATAGTACAGAAAGCTTACCAATACTACCGTTAAAACTATTTTTAGGAGTAAAA TAAGTTACATAGGAACACTGTTGTGAGATGCACACAACTTTCCCTTTGAAAAATTATCTG CTGTTAACTATATTCATTTTCTTTCAAGGTACATGTCACCTGCAAAATTAGGAGAAGATA TAGTGATTACAGCACATGTTCTGAAGCAAGGAAAAACACTTGCATTTACCTCTGTGGATC TGACCAACAAGGCCACAGGAAAATTAATAGCACAAGGAAGACACACAAAACACCTGGGAA ACTGAGAGAACAGCAGAATGACCTAAAGAAACCCAACAATGAATATCAAGTATAGATTTG ACTCAAACAATTGTAATTTTTGAAATAAACTAGCAAAACCAGAAGCAGCTAGAAATATTC TTGGAGGAAAAGGACCTGGATATCAAGTAGGGTAAAGGTGGGGGTGTCTTTTTTCACTTT AAGCATCTTGTTTTCTAATCATGTGTGATAATTGGGTGAAAAATTCTTAGCTCAAAGTGT TTTAAAAACAGGTAAAGCAAAGAAACTAGCAGGACCACTCTCAGTTAAGATTAAAACTAA AGTCCAGTGTTAAGCTAAAGGAGAAATAGAAATTAATGGTTCTAATTCTGTTTGGGCTGC TAGGAACAACAGAAATTTTTCATGGTTCTAGAAGCTGGAAAGTCCTGGGTCAAGGCCCAG CAGATCCTGTTAGGTGAGGGCCCGCTTCCTGGCTCATAGATGGTGCCTTCTCACTGTGTG GTGGAAGGGGCAAGTGAGCCCTCTGGGTTCTCGTTTTTGAAATGGAGTCTCGCTCTGTTG CCCAGGCTGGAGTACAGCAGCACGATCTCGGCTCACTGCAATCTCTGCCCCCTGGGTTCA AGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTATAGGCATGTGCCATCACACC TAGCTAATTTTTGTAGTTTTTTGTAGAAACAGGGTTCACCATGTTGGCCAGGCTGGTCTC GAACTCGTGACCTCAGGTGATCCGCCTGCCTTGGCCCCCCAAAGTGCTGGGATTACAGGT GTGAGCCAATGTGCCCAGCCTGGGTTCTCTTTTGTAAGGGCACTTACTCCAATCTTGAGG GTTCTGCCCTCGTGATCTAATAACTTCCCAAAGACCCCCACCTGCTAATATCACCTTGGG GGTTGGGATTTTAACATACAAATTTAGGGGAAACACATGGAGACCACAGCAATGGCCAAT CCTTAGCGAATCTTAGGTCCTTCCCAGATCTAAAATGCCAAGCTACACTTGCATTTCCTT TTTTTAAGATTATGAAACTTCAAAATATATGAACTACAGCCCATATTGAAAAATAAAATA GATTGAGCCATATGCCTAAAAAAGACCTCAAGAAAAGTTTGAGGCTAAGCATGTTAGTGT TACAGGAAATGGTCCAATAGAGGGGGAAGAAAAAAAGCATGCTACTAGCCCCTTTTCTTG TACCGAGAATAAAACCATGCAGATCTCAAACCTCCAAGTCTATAGTATTGAAAAGACCAA GTTCACTTCTCAGAAGTCTCCAAGTTCAGTTGACTGTGGCACTCTGAGACAGCTTCTGTC ACTCAGGCTGGAGTGATACAATCACAGCTTCCCATAGCCTCAAAATCCCAGGCTCAAGAC ATTCTTCCACCTCAGTCTCCTGAGTAGCTGGAACTACAGGCGTGTGCCACCACGCCTAAT TTTATTTTTGTAGAAACAAGGTCTCACTGTTGCCCAGCCTCGTCTCAAACTCCTAGGCTC AAGCAATCCTCCTGCCTTGGCCCCCCAAGTACTGGACTTACAGGTGTGAACCACTGCACC CAGCTGACTCTTACTTGATTTCTGTCAGGGAATCTTAATGAACATTTCATGACTAAAGAC TAAAAAGGATGCAGCTTTAAGTAAATTTAAGTCAAGTTAACAGTTAAAGACAAATCCTTT CCCTACATTAGATCGCCTGCTGATCTGTCCACTGTGAAAGGGCAGAAGACTCCACAGTAG CAATAGCAGCAGTGAGCATACAGGAGTCCCAGATGTTTACTTCTAGTATTTCCCACTAAA AGGAAGCTGGGCTCCTTGGAGAAACAGCTGACTCCAGGGCTTGAGGCTGGGACAGAAAGG TTACAGTATCTTATGCATGAAAGGAGATGCTCAAAATAATAAAGGCATGCAAATTATGAT TTGGAGGGAAAAAATATGAGGCCATAGTGTTTAGGTAGATAATAAATGGCAGAGATAGAA CACTCTCTTACAACAAATGCTGTAAATGGACAAAGCATTAGATTTGGAAAATCACTATTT TGTAACCATCATAGTTAAAGACTGGTTTGGGTTTTAGTCTGGAAAGAATCGCCAAGGGAG CTCCTGATAAAGGAACAGGGTATTTGCACATTGCTTCCCAGAGATTGCTAGTAGTAAGTA CCACACATAGGGCAAAACCAGGACACCTTGACCAGGCGCTCAAAAGTAACATCAATGAAG AGCAGATGGAGAGTATACTTGAGAAGGGCGTTAAGCATGAATAAACAATTCAAATGCAAA ATGAGTAACAATTTACAAGAAAAATTGCCCTGTACTCCAAAAAACATAGAGGTCATGGAA CACATAAAGGCTAAGGAACTGTTCCACATTAAAGACAACTGAGAACAACTAAATTCAATG ATCCTGTACTCTAGAGGGGGGGATCTAAAACAAGCTACCAAGGATACTGGGACAACAAAA CGAATATGGATGATAAAGAGTATCAACATTCCCTGAGTTTGGTAATTTTACTCTAGTTAT ATGAAATATTCTTGTACTTGGAACATATGCCGAAGTACTAAGGAAGGGGTAAGGAAGCAC AAAGTGTGCAACAAACTCAAATAGCTCACAGGTATAAGTGTACAGAGAAAATGAAAAAAA TGTGGCAAAATAATAAAAATGAGGGTAAAGATTACACAACAGCTTTCATATTACTCTGGT AACTTTTCTAAATTATTCCAAAATAAAAACGTAAACAATGGCTGCCAAAATGCCTAACTT GGTGAACATAAGTGTAATTCAATATGGTAAATTAATTCAACATGGTAAATTAAGAGCATA GGCCTTAAGAGCCAGCCAGCCTGGTTTTAAATCCTCCACTACTTATGATCTGAGCTTGAG CAAGTTACTTAACCTCTGCATCTATTTCCACCAAAGGTTGAGAGGTTAAGACAAGAGCTT AGAAGAGTACCTGGTTATAATAAACATTCAAAATGTTATTTCAAATAGATTCTAATTTTT AAATAAGAGGACACATGAAAGCATTTTGAAATTTAAGAATGGCCCTTTCCCATGAAGCAA GGCATAAGGCCAGGTTGCTAACTGTTGAAAGCTGACAGTATGTTCTTGATTCCTGTTCTT GTTGAAGTTACACACTCAATTGCCAGGTATTTTTCTTCTGAATTTACTATTTAGCCACAG ACTATGAAATAATTCTCTAAGGTGACCAGTAACATCAGTGAAATGGAAAGAAAAAGTTAA CACTTCAAACTTTGTGTATTCACCTGAATAGTCAGGGAACTTTCACCTATTTTATTTAGG TTTTCTTTTTCTTTTTTTCTTTTTTTTTCAAATTCCAACCAGAAGCTAAATACAATTGGA AACTGGTAAGCACTAGTTTTACTCCAAAGGAGTAGGATCATTCAGATTTACTCCAATAAA AGTATGCAACCCTTAAGCAAAGCTTTTCTTCATTTA bcftools-1.21/test/csq/ENST00000230048/ENST00000230048.fa.fai000066400000000000000000000000211467060157400215120ustar00rootroot000000000000006 38016 23 60 61 bcftools-1.21/test/csq/ENST00000230048/ENST00000230048.gff000066400000000000000000000026111467060157400211370ustar00rootroot000000000000006 ensembl_havana gene -15 38015 . + . ID=gene:ENSG00000112304;Name=ACOT13;biotype=protein_coding;description=acyl-CoA thioesterase 13 [Source:HGNC Symbol%3BAcc:20999];gene_id=ENSG00000112304;logic_name=ensembl_havana_gene;version=6 6 ensembl_havana transcript 21 37996 . + . ID=transcript:ENST00000230048;Parent=gene:ENSG00000112304;Name=ACOT13-001;biotype=protein_coding;ccdsid=CCDS4558.1;havana_transcript=OTTHUMT00000040010;havana_version=2;tag=basic;transcript_id=ENST00000230048;version=4 6 ensembl_havana exon 21 294 . + . Parent=transcript:ENST00000230048;Name=ENSE00001174688;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001174688;rank=1;version=3 6 ensembl_havana CDS 214 294 . + 0 ID=CDS:ENSP00000230048;Parent=transcript:ENST00000230048;protein_id=ENSP00000230048 6 ensembl_havana exon 30833 31017 . + . Parent=transcript:ENST00000230048;Name=ENSE00003657839;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003657839;rank=2;version=1 6 ensembl_havana CDS 30833 31017 . + 0 ID=CDS:ENSP00000230048;Parent=transcript:ENST00000230048;protein_id=ENSP00000230048 6 ensembl_havana CDS 34409 34565 . + 1 ID=CDS:ENSP00000230048;Parent=transcript:ENST00000230048;protein_id=ENSP00000230048 6 ensembl_havana exon 34409 37996 . + . Parent=transcript:ENST00000230048;Name=ENSE00003680711;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00003680711;rank=3;version=2 bcftools-1.21/test/csq/ENST00000230048/ascii-art.txt000066400000000000000000000000641467060157400212560ustar00rootroot00000000000000 6:214 AT A ....eeeeeee CACGATGACCA CACGA-GACCA bcftools-1.21/test/csq/ENST00000230048/start-del.txt000066400000000000000000000001711467060157400213000ustar00rootroot00000000000000214 AT A start_lost|ACOT13|ENST00000230048|protein_coding|+ 214 AT A start_lost|ACOT13|ENST00000230048|protein_coding|+ bcftools-1.21/test/csq/ENST00000230048/start-del.vcf000066400000000000000000000006351467060157400212440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 6 214 . AT A . . type=ENST00000230048:24667492-AT-A;EXP=start_lost|ACOT13|ENST00000230048|protein_coding|+ bcftools-1.21/test/csq/ENST00000256452/000077500000000000000000000000001467060157400166505ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000256452/ENST00000256452.fa000066400000000000000000001613361467060157400210130ustar00rootroot00000000000000>3 3:3111213-3168317 GTCTCTTTTGATATGGGGTGATATATTAGCTCTATTATGCTTTTAAATTAGTTGGTTTCA AATGATGTATCCTGGATCAGGCCTCTGGAGCTTGAGATAATTTCTCTCTCTCTCTCTCTC TCTCTCTCTCTCATACACACACATACACAATCTACCTAGAAAAAGATCATTCTAGAATGT AGGGGGGTGAGGAATTTGTGGCTCTCACTTGCTATAGAAAAGACAGTCTTGAATCCAAGT TCATGGTTCACTCCAGGCTGATGCAAAATGCTTTCTTCCTCAGATGGTAGCTGAGTGCTA CAATTGGCAGCTTAAACAGCCAAACGGGCACAGCCAGAAGTAAATACAGCTGGACGTTAG CCTTAAAAGCTGTCTGTTGTGAATGAAAAGTCTGAGGTGAGTCAAGCAAATTGCAAAGAT TGGCAGGTGAGGAGGTGCTACCCTGTACGGCATGGGGAGAAAAAACATGGCAAAATGCTT GGATGAGTCAACTTCCCTGCTGTAGGTGAGGCGATTTGGATGAAGCATCCATACTTTTAA GAGATACAAGACTGGTGTGTCTGGGTGTATTGCTTCGCAGGTAAATTGAGTGTTGCCTAA ATTCTGAACACCTCTTAGCCAAGAGCCAGCATCCCTGTTCTTTTCACTGAGGCACTGAGG CATGTGTGAGTTCATCAGAGGATGCCAAAGTGACAGTCAAAACACAGAATCCTCCAGGGT CTCAACTCCAGGCTTCTCTATATAACAGATGACTTCAATTTCCGTCTCACTGGACCCAGC TTTCTGCAAAACAAATCATCTTTCCTTAGATGTCTTTTAGAGAACTTTTGGGTTCTTTGA AATCTTTACAATTGGCTTTAAGTCTATTATTTTTTAAATAAAAATAGTAAATGTTCACAA AGAAGATGTGAAAAATAAAGTGGGAAGAAGAAGAAAATACCTAGCCATACATCTATCTCC CAAACACAGCCCACTGCTTCTCCTAAGCCTTTCTTTCTAGGCATAATGTTTTCTTTAGAC TTACTTGAAGTCATATGGATACACATCTTTTTTTTTTTTTTTTTTTTTTTTTAGACAGAG TCTCACTCTTGTCACCCTGGCTGGAGTACAGTGGCATGATGTCGGCTCACTGCAACCTCC ACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAAGTA CACACCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGAAACGGGGTTTCACCATGTTG GCCAGGCTGGTCTCGAACTCTTGACCTTGTGATCCCCCCGCCTCGGCCTCCCAAAATGCT GGGATTACAGGCATGAGCCACCACGCCCGGCCGGATACACATCTTTAAAAATTGATTTTT TTCTCTCTGACATCACTGATTGTAAATTACATTGTTAAATGTGCTTTGGCGGCATCACTT TTGATAGCTTCATCATATTCCTTCCATAATTTACTACAGTATCCCCCTAACTTTGGACAG TTCTGACCCATTTTGGCTATAATGAATAGTGCTGATAATAATTGGAAAATTGGTAACAAA AAATAAAATTGCCTGTAAGAGATCCTATTCCTTTATCTCATTTACTCATCCAAAATATTT TTTACTATCTGCTCCACACTAGCCACAGTGCCGTGTCTCGGGAATTCACTGATGCACACA GCAGGCATGGCTCCTGCCTTTATCCATTTTACTGTTAATAGTTTACGGGCAACCTAATTG GAGGAGGAACCCTCTCTTGGCCATTGTAGAAACAAGGAACAGCTGGAAACCAGTCTCATA AATTGAAAGCTCAGGCCAGGTGGCGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGC TGAAGCAGGCGCATAGCTTGAGCCCAGGAGTTGGAGACCAGCCTGGTGAGATCTTGTCTC TATAAAAATTGTCTAAATAAGTAAATTATCAGAAAATTCAGGATATGCTTTTTTAGAATA AGCCTTTCTTTTTGACTGCTAAAGGCCAACTTTCTTCCTTCACAGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTGGCAAGTTCTGGCTACATC ACCCAAGCTGCAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCCGCCTCCTGGGCTC AAGCCATCTTCCCACCTCAGCCTCCCGAGTATCTGAGGCTACAGGTGTGCACCACCGTGC CTGAGTAATTTTTGTATTTTTTGCAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTTT CAAACTTGTGAGGTCAAATGATCTGCCCATTTTGGCCTCTCAAAGTGCTGGGATTACAGG TATGAGCCACTGTGACCGGCCCTTCACTGACGTCCAAATTTCTAACTGAGGTCTGAACAA GCAAAAACTTGCTTCTAGGGTGGCAGAGCTCCTCTAAGTCCTGGGACTTTGGGCACCCAC CCCAAGCTCAGAGGTGCACATTACCATGAAAAGCAGAGGGTTTCCTTTCCCACTAGCCAA ACATTTCCCAGTGGCCACTGCCCATAGCACCAATGTGCCCTCTTGTCACCCTTGTAGCAC AGCCTCTGAGAATGGGTTGGATGGCTTTTGTCCTTGGACGTGGAGGCTGTGCACGGCCTC ATGGGGCCCAGCTGTAGGCAGCTCTGCACTGGCTCTCATCCCCTCTCAGGTGGAGAATTT AGGCCATAGAGCCCACAGCACCAGGCAGTACTTCATTTCTCCCATTCTGTGTGCTCTTTC TTTCTTCTCTCAGTCTCTAACTGCTTTGTTTTTATGTGAAACTCTGCAATGTGAGAAGAG AATAAGTTGTCCTGAGAAGCCAGGCGCTGTGGAGTGCCGTCATTCATCCTCTGCTTATTC TGAAACCAGCTTGTCTGCCCCAAGTTGTTATTTTACACACATGACTTGATTTTAATTAAC AACAAATCACAACCTTATACAATAAGCTTTTATACCAGTTTATTTCACCAACTTCGGAAT ATTAAAGGAAATCTTTTGGGGCTCTGTAGGGAAATTAGATACCAGCATTAAGATGTTCCA TTAAGAGGCCAGGACAAATGACTTCAGTTGGCTGCTTAAACTAGATGTGGGCTGGGTGCA GTGGCTCATGCCTGTAATCCCAGCACTTTGGGAAGGCTGGATCACTTGAGGTCAGGAGTT CAAGACCAGCCTGGCCAACATGGCGTAACCCTGTCTCTACTAAAAATACAAAAATTAGCT GGGCGTGGTGGCGGGCACCTGTAATCCCAGCTATATGGGAGGCTGAGGCAGGAGAATCAC TTAAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATGGTTCCACTGCACTCCAGCTTGG GTGACAAAGCGAGACTCCATCTCAAACAAACAAAACCAGATGTGGTTACTCAGGGGTAAG TGTGCTAGAGCAAGGAGGGACTGGCAGCACACATCCAGAACAGGCACCAAAGCTCCACCC TGGGGCCCACTCTTCTTCCCAAAGAACTCAGTGAACAAGAGCAGATGGGCCATTCCCCTG ATAAAGGAGAACACAAAGATCCAACCATGGGCAGAATGATTCTTTTGCCAGCCTCCATTC TCTACTTCAGTCAGCTAGTAACTGTAACTGTCTATAAATCCTTCCAATACCCAAACTGCA AATGCTAAGGAAAGTTCACCACTTATTGAAATTAATCATTTTGGTGAGTTTTTCCACGAA CGCTTTCTTTTCCCTACAACCAGTCACCAGGTGGTTCATCCAATCATGAGTTACTTCATT TGAGAGAAACCTAAATTTGCTAAGAAAACTGTTTGATCTAAATCAAGGGTTGGCAAACTA CAGCCGCGGGCCAAATCTGGCTTGTTGCCTGTTTTGGAAAATGAAGTTTTACTGGAGCAC AGCCACGCTCATTCATTAGCACATTTTCTGTGGCTACTTTCACACTACAATGGCAGAGTT GAAGAGGTGAGACAGAAACCATTTGTCCCTCAAATATTTACTACCTGGCCCTTTACAGAA AAAGTTTCTTGAGCCCTGATCTAAATAACCGTTCACCTTAAGGATAAATTTGACAAAGTG CAATAATCATACACTGAAAAATCACAAACCATTGCTGAGAGAAGGTAAAGAAAACCTAAA TAAATGGAGTGATATGCTATGTTTATAGATAAGACTTAGGATGTCACTTTTCCCCAAATT AACTGACAACTCAACACAATCTCACCCCAAATCCCAGCTACCTTTTTTTGTAGAAAATTG TCAGCTGAATCTAAGATGTATATGAAAATGCAGAGGACCTACAATAACCAAAACAAATTT TTAAAAAATCACTTTTGGAGGCCTTCCACAAATGGTCTCGTGGTTTACGATAAAGCTACA GTAATCAAGACAGTATTGTATTGGCATAAAGATAGACAAATAGATCGATAAAACCAATCA GATAGTCCAGAAATAGAACCAACTACATACAGCAACTAATTTCCTACAGAAATGCCAAGG CAATTCACTGGGGAAAGGATGATTTACTCCAACAAATGATGCTGGAACAATTGGAGAGCC ATAACTAAGTGACCACTGGGCTGAACCTAAGCGCTCTGAATGGTGAACAGGCCTAAGAAA ATGCATATTGGGTAAAATAATTTGCCTTTTCTATGGTCTTTTTTATACTAAAGAGCTAAA GTTCCCTCTGAAAATTCTCTATTAACTAAGATATTCATGTGGAAACATGGAGTCTTAAAA CATTAGAGCTAAGCAGAACATTGTACAATCTCATCTGTGTCCCTTATTATACCAGAAAGA AATTCAGAACTCAGAGGGTTGAAGAGATTGTCCAAAGTCAGTTAAGGCATGGCTGATATG AAATTAAAATTTAAGTCTAACTGTCAAGAACACTTATAACTCAGTACCTTTCCAATATGT CAGAAGAGTAATGAACGTGCATAATAAAACAATCAGGCAAGCAGGCATGGTGGCATGCTT CTGCAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCGCTTAGACCCAGGTGTTTGA GACCAGCCTGGACAACATAGCAAGACCCCATCTCTTAAAAAATACAAACAACTGAATCAG CCAAAGAACAGAATGACTGAAGCAACAGAAATGCTCCTGGCCTTCTGAGTAAAAACCCTG CCTTATAATATAGAAAACTAAGAACCGAATGACAGCTCCCAGGGGACTCAACCCTGGACA CATACGGCATATCATAAGAACTTTCAACATTACCTCATAGTTAGTGGTTACAAAGAGATC TTTGATATTACTTTTTGGTGCTGGAATTGGTGGAAACAACTTGATCCATAAATGACATCT GAAAACAGAGTAAAGAAGGAATTAGGTGAGCATGAGTATACCTTTTGTCTCTAAATATCT ACTCTAAAAATTGACCTGGTTGATTCTAGAACCTGCTGTTTTGTAAATTCAAAATCTTTA CGTACCAAGACTTCCAAAATTATAGGTGAAGACTTTGTGGGTACCGCAAGCCTCTGCTGT GGCCCTGAGTCATCCAGGGAAGACCAAATGGAAACTGCTTTGTGTCAGTGGGTGTTACCA GGCCTAATATCTGAAAACGAACTGTATATTTCAAGTGGGTGGTGCTGATTGAAGCATTCC TTCCTCAATTATGTTTACTCACAGAGTTTACTTACTTTTTTTTTTTTTTTTTTTTTTTTG GTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCGTGGCTTATTGCAATCTCC ACCTCTCGGGCTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCA CATGCCACTGCGCTCAGCTAATTTTTGTATTTTTTGTAGAGACAGGGTTTCACCATGTTG CCCAGGCTGGTCTCGAACTCTTGACCTCAAGTGATCCTCCAGCCTCAGCCTCCCAAAGTG CTGAGATTACAGGCATGAGTCACCATCCCCAGCCGAGTTTACTTTCTTTTCATCTCCTTT GTACTGCCTTCCCCCAAACTGTAGATGCCATCCGAATATAACGTTTATAATAGTAAAGCT GTTTAATAGAAAAGTCTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCCCCCAGGCT GGAGTGCAATGGTACGATCTTGGCTCACTATAGCCTCCAACTCCCAGGTTCAAGTGATTC TACTGCCTCAGCCTTCCAAGTAGCTGGGAATACAGGCACGTACCACCACGCCCAGCTAAT TTTTTGTATTTTTAGTAGAGACGGGGTTTCACCACATTAGCCAGGGTGGTCTCGATCTCC TGACCTCATGGTCCACCCGCTGTGGCCTCCCAAAGTGCTGGGATTACAGGAGTGAGCCCC CACACCCGGACCTTATAAAACTCATTTTCTAAATTATGAAAGGGCCAAGACAAAACATGT TTTTAAGCCTCCTAAAAGGTCTTGTGCCTTACTGAATGCTAAAATGGGTAAGGGATACTT ATGGACCATTTGTGGACTCTAGGATAGGATACCAGATCCACATGCGATTTCTAGAATCCG TGTTTGACCTAATAACCATCAGCCACTCAGGGGCCTGGTGACTTGATAGCTGAGGATGAT GACATGCAGGCATTGTGGTGATTTTAGCCTCCCTGAGCTGTGAAAAGCCTATACTGGCAG CTTACCCTAGACAGCCAAGGACCGAGTGGAAGACTGAGAAGGAATCAAAAGAAACCCGCA AGTAGAAACCTTCACAGAAATTAAAAGCTGTCGACAACTTCAGGTAGGAGTGAGTGATAG CTGAGGGCTGCATTGTGTGCTCTGTCCAACTTCTGTAAATCACCTCTGGACATTTCCACT TTTGATTTGGCCTACACTCATCTTGGACAGGTCATCTAGGCACAAAAATGCCACAAATTT TACCTGATAATAAGAACCCTCTGCCTACCGGATGCATGGTAAGCCTGTAAAAATGCAGTA CTGAAACCCCACTGCAAGCACGCAAATGTAAAGAACACTTACATTTTACAGATAAGCGAG AGAATTAACAAGATGAAGCAGATGGTTGCCATAATCACAATGACAAACCACTCTCTCAAG GGCTTGTGTTCATCATTTCCTGGTGGAAAACAAAAAAGAAACAAAAAAATATAAAGTCCA AGTTAGAAGCAGCAGGTAAAAGAAATGATGAGGCTTGGGTCATCAGACAGCTCAGGTTTG AGTTGCCGGTGCTGGGTGGTGTTGGGCAAGTAGCTTAACTTCCCTGAGCCTAAGATTTCT CATCTGTAAAAGAAGGGTAACAGCCATCTCACAAAGTTGATATAGGGTGAGATGAAATGA TGGCAGTGAGGCCACTTTTATTCTTAAAGAATGATTTATTCAATCAATCAGCAAATATTT ATGGCATTCATTCCATGTACTGTGCCACTTGGATCTTGGAGCTTATCTGTTTTTGGTACG TAGTAAGGTTTTTAGATAGAAAATCCACAAAAAGATAAGCCTATTGAGTAACCCAATGGC ATCACAATCAAAATACAAAGTTGGAAATTAAACTTTTGGAGGAAGTAAAGTATGAGATAA TACTTGTAGTGAACAATAAAGGCATCAGACTCCAAGTGCTTTTCAATCTTAAATATCTTC AAAGCACCCCTTACCATTATTCCCATTTTACAGACATGAAAGGAATAAAACTGCCATTAA GTCAGTACAGAAAGTCAGTATTTTGTATGCCACTTATTCTCTGTTTAAATTTGCTTTGAA TCTACATTTAAGGGACAGATTCTTCTAGGAACTTCTTTTTTTTATTATTATACTTTAAGT TTTAGGGTACATGTGCACAACGTGCAGGTTTGTTACATATGTATAAACGTGCCGTGTTGG TGTGCTGCACCCATTAACTCTTCTAGGAACTTCTATGATAGCTTTGGGGTGTGTAATTTT TCTTTTAAGTACTAGAAAGGCGTCCAAGACAAACTCAAGCCAAGTGCAGTGGCTCACGCC TGTAAATCCAAGCACTTTGGGAGGCTGAGGCAGGTGGGTCATTTGAGGCCAGGAGTTTGA AACCAGCCTGGCCACCATGGTGAAATCCCATCTCTACTAAAAATACAAATATTAGCCAGG CGTGGTGGCAGGCACCTGTAATCTCAGCTACTTGGGAGGCCGAGGCACAAAATCGCTTGA ACACAGGCAGCAGGGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGTCTGGGGGA CAGAATGAGACTCTGTCCCCCACCAGCCCCCCTGCAAAAAAAGAAAAGAAAAACTCAAGA CCATTTACCAAATAGTGTTTAAAGAGGTTATGTGCTTGCTAACCTGCCGGATTGAATAAT GTAAATCCTGTGTCATCTCCCTGAATATGAGTTTCCTTTCCGTGGGAGAGGCTGCTCATT CATTAATTCCTTTATTCATCCATTTAACTAATATTTACTGGGCTCCTATTATATGTTTGG AACTGTACAAATTACTGGGATTCAGTGGTCGAAAGATCACATATGGGTGCTCCTGTCATG GAGTCCATTAGGAAAGAATCACACTCAGCAAATAGCAACACAAGCAGTGATTTAATGACG AGCGTGCTAAATACTGTGGTGAGATTTCAACCACACCGCACCAGGAGAAAAGGTTACCAT GCTCAGTTTGCCATGAACTGCTTCCTCTAGAAAAGAAGAAATACATAAGTGGAATTTTCA GGTCCTTGTTAATAGCCTAAGACTTCCAAAATAATTAAAACTCAAATCATTCAAGTGACA GGAAGGAGAGATACCTTGGGATATAATGCTAGTGATTCCAGCCTTGCCTTGTTCTCTTGC TTTTTTGCCTCCTGAGGACCCTTATCCAAGCTTTATCTTCTACCTCCCGAAAGTTTTAAT CTCCTTCTTCATCTCTTCCCTTCTGCTTTCAAATATTCATAGAGTCCTTCATCTTGAATA AGCCATGACCCTGCTTTGCCATCTCTCTCCACTGTCATCAAATACCTTCTTACTTTATTT CCCAGTCTAAATTCTTGAATAAGGGCTAGGTGCGGTGGCTCACGCCTGTAATCCCAGCAC TTTGGGAGGCTGAGGCGGGTGGATCACTTGAGGTCAGGAGTTCAAGATCAGCCTGGCCAA CATGGCAAAACCCCATCTCTACTAAAAATATAAAAATTAGCAGGGCATGCTGGCTCATGC TTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGACAATTGCTTGAACCTGGGAAGTGGA GGTTGTGGTGAGCTGAGATCCCGCCACTGCACTCCAGCCTGGGTGACAAGAGCGAGACTC CGTCTCAAAAAAAAAAAAAAAAAAATTATTTAAGGGATTCGGGCTGCTTCATTTCCCAGC TCTAACACTGCTTTTTTAATCACAGTGACTTCCTCCTAGTCTAATTCAAAAGACGCTTGG TTTCTTTTTCCAGCTTTATTTTTACTGACCTCCTTCCTGAATTTCAGACTGTGTATAGTT GAGCCCACCTTGAAACCGAGTCCTCAGCTTTATTGCCCATATCTCTTCTTAGATGGCCCT TCTCCCCATTTTAATTTCGATTGGCCCTCTCCACTCATCCTTTGACCCTTTGCTATTTTC CACTGTGGCCTATTCTTTGAACTTTGAAAAGTTTGTTTATACCACTTCATCTTTTAATTT TATGAAGTCTTTTCCCAGGTTTTTATTCCTGGTCCTGCCTGACACTCAGCTCCAGGCCTG GATCTTAAACTGTCCGTAGGTAAAACCTGCTCGGATGTTTCTCAAGGCTGACAACATTCA AAACCAAACGCATGTTCTTCTTCATATAAAAACCCCTTCTCTCACTAACTGCCCATTTCA GTCTCCATTCTTCCAAGCCCCCAGACCTGAAGCCTCGAAGTCACTTTGACTCTTTCCATC CTTTACAGCCGCTGTCCCTTCTCCTCATTCCCTTGGTTCATGTCGTCACTGCGTACCCAG TGATTAGTGCCGGACAGGCAGGCTTTGTCCAGTGCTTTCATCCCTGCCTATTCTGGAAAC CTGGCTTGTAGTCTCAGCTTGCTGTGAAGGTGGTCATTCTGGGCCTCGGTTTCCTCATCT AAACACATGGCAGTTGAAATATATAATCCATAGATCCTTCCCCAGCCAGCACCTTTTCTA GCACCACTCACTCAGTTGAGGGTACTGTCACTTCATGTACACATACCTTTAATAAAATTG GTTTTAGAAAAGCAGTGCCTTTTTGGGCCGGGTGTGTTAGCTCATGCCTGTAATCCCAGC ACTTTGGGAGGCCCACAGGCAGATCACTTGAGGTCAGGCGTTTGAGACCAGCCTGGCCAA CATGGTGAAAGCCCATCTCTTCTAAAAATATAAAAATTATCCAGGTGTGGTGCCGCATGG CTGTCATCCCAGCTACTAGGGAGGCTGAGGCAGGAGGATCCCTTGAACCTAGGAGGCAGA GGCTGCAGTGAGCCCATCACGCAACTGCACTCCAGCCTGGGCTACACAGCAAGACACTGT CTCGAAAAAAAAGAAAAGAAAAGAAAACAAAAGTAGTGCCTTTTTGCTGCTGGAACTTTA AAAGTTTATAAAGTATAAAAAAGAAAAAAGAAAAATCAGTAGTCACTGGAAGTAACTAAG AGCTTATTTTCTATACATATTTTTGCATTCGCTTTTTCTGAGTGCTTCTAGGTGCTCAGA TACTGTGTAAAGTGCTTCACGTACTTTCTCGATTTAATTCTTACAGCGATGCTTTGAGAT GGACACTATTATTCTCACTGTACAGATGGAGGAACTGAGGCAGAAAAGGACAGAGTAAGT CAGCCCAGGCCACACAGCTAGGAAGTGCGGAAGCCCAACCAGTCCGTGCTCTTAGCCTTG ATGTAGGAATCCCATTCCCCTCCCTCCCTCTGCAAAACTGAGGGCACACTGAATACATAG GAGCTTCGCTTCACTTATTTTAAGCATTGCTTTTCATTGAGAACTCTCCTGAGCATGATC CCTATAGCTCTCTGTGCTTCACTGTGGGAAGCCCTGTTCTATTGTTTGTATCCCCGTTTC TGATAAGGCTAAGTGTGCAGGCAGCTTCTCTAATTAAAGGTGGCTGCTTTGCAAACTACC GTTTCTCCTGACATTCCCCAAACTCTAGGTGGGACTGAAGCCCTTTATTAAAAACCTATG GCTATACTATTTATTTATTTATATGAGATAGAGTCTTGCTGTATCACCCAGGCTGGAGTG CAGTGGCATGATCATAGCTCCCTGCAGATTCTAACTCCTGGGTTCAAGCAATCCTCTCGC CTTAGCCTCCGAAGTAGCTGGGACCACAGGCACGCATCACCATGCCTAGCTAATTTTTAA AATCTTTTGTAGAGATGGGGCCTCAGTATGTTGCCCAGGCTGGTCTCAAACTCCTAAACT CAGGCAATTCTCCCACTTTGGCCTCCCAAAGTGCTGAGATTACAAGCGTGACCAACTGTG CCTAGCCCTATGGCTATAGTATTTTTTTTCAAGTTTTTTTTTGAAATATACTTATGTCTA TTGTTTTACAAAAAGGCATTAGCCACATTTTGTTAAATAATGGAAAACAGACCCTCAAAG TGGCAAAGCTTTTGTCTTCCTAAATCCTACAGATCCTCGATGGTTCCAGGATTAATACTC CGTTCTCTGGATTGGAACTGAGGGCTCTGTTAGACTTCATTTTTATTGCATTCTTTCTTA GTTAATGTAAAGAGTAGCTGGGACAAACTAATAACAGCAAATCAAATACCGTCTTACTTT ATTTCCCAGTCGATTTCCTGAGTAAGGAATTCAGCCTGCTTCATGGCCCCATCTCTGAAA CTATTCCATGCTCGTAACCATTATGCAAGTATTCTGACAACCACATTCAGAAACTGCAGG TTTATAGACACCGGATGCAAATTCAGCAAGTGGTACATCAGCAGAAAAAAAGTTATCCTG TTTATAACTAGGTTAAACCAACAGAAAAAGTGTGGGTCCTGCAGAAAGAAGGGGCAGTGT TGTAAATAATTATCAGGGTCACACTGTCAGTCACATTTGGGTCTCAACTTGTGCAATATC CCCTAGCCTGATATGGCAAGTTTTGATAACAGTACCGTTTTCTTCTGACCATGATTACAA AAATCTTTTCAGTTAAACCACTCTCAAGTTATTCACTTCAGCCCTCACTTTGATAAGCGA AGATTCTCACTGAATTAGCAAAAATATAGAGGCAACCCTGATTTTATTTCATTAAATGAA AAAAAGTTATTGATGCATACAAGGTACTACGTGAGAAGCAAAGTCACGGTCACTGCCGGG AGGGAGGTGGCACATTAGTCATTTCTCCTGGCCTGGCCTCTCCAGTTGCCCCAAATGCAT TAGGGCTACTCCCCTATAGCTAGTTGAAAACAGAACTAACCCCTGAAAACACAACCAAGG TCGGCTTTTCCTTGAAGAAAACATAAATTGGCAGGAAAATTTTGTGCAAGCAAAAGATTT CACATACCTATTGCGAAGTAGACATTACTTGTGGATTATCTACTGTTCAGTTACTTATTT ATGCAAAAAAAAATGCCAGTACATTAGTGAATTAAAGTAAGCACCTGCTCTGGTTTTACT GAAAGTAGAGCAAGGAGGGAAGATCCCACTGAGAGTATACATTCTTTGGGTCAAAATGAT TAAGAATTTCAATACTATAAAATTTGGGAGATCCCGTAGTATAGTCTTAATTTGAATTCT GGGGTCTCCAACCTTGGAGATTAAAAAAAAAGTATTTCGAGGTAATTTGACTCTCTGCTC TGACTCAAGGAGAATACCTTTCTTGCCATTAAAAAGGAAGTCACAGATGTTTCTTTTCAA GAAATCAATGGGCACTGCCATTTGGTTATGCAAAGATGGGTTTCAGAAAGAAGAAGTCAC ACAGCCTATTCTTGTAAGGAGGAGAAGCTCTCCAGACTCCCCATTTGATTCCTGGGTGCT TTTTAGGCATCACTAACGTAAAGCATTTGGGAAATTCAGTTGTCTGGTGTCTGGGGACCT CAGTTTCCATTATTTTTGACATCTTAAGCATTTGACCTTGCAAATAAGCCAATAGTCTGC TATTCTTCTATGACCCTAGAATGTATATGGAGTGGGACATGGGGTGCAGGTGGGCTGGGA CAGTGGCAACACAGAGGGCAGAAGGACTGCAAGTATTGGACCCAAACTAGTCCCAGCTCT GCCTCTGGGAGCTTTGTCAAGCCACTTCCCTTTTAGGGCTGCAGTCTCTCTTGATCTAGA ATTCTATGATGTATGAAGTTTAGACTACTAGCTCTTAGGAGATGAATTTGATTTGGAAGC CTGTTACACCTTAAATTCTGCATGTAAGTATGAACTTTCAGTGCTTACATATTGATTTTG AATCTGATTTCAGACTCAACAATAGGTTTCCAGGGAAAAGAGCTAATTAGTAAATTGATG GGATGCTTCCAACAGAGCAGGCCTGCTGTGTTTTTAGAGCCAGCAGGTGCTGGGAGAAGT TCAAATGGCACCAACAGGGTTGGATAATTGAGAGGATGTCAATATGGCAGTCTATGATAC AGGGTTTAACTAGCTTCCTGTGACTTGCCTCCAGTTGGAGGGGAGAATGGCATCATTCAT GAATGAACATCCCAAACCAGATCACAGGCTTCCAGTGCAGGCAAGTCAGGAGCAGACCTT TTGGGTGAGTGAGCTTTCAAGGCAGCTGTCAAATGGACTGTGGGAGGTACCTGGTTTAGA GAAATAAAAAGAGGGCAGCAAAATGCAGCCTCAGTGAACAAAATGTGTAGAGTAGTGAAG GACCCGGATCACACACACAGCTTGCACTATGTTCATCTGGTGGAACTGGGCTTGCATTAA CCGAATAGAGAGAGGAAATGGAGACTGTGTATTTGTGTACGTGTGTGTATTTGTGTGCAT GCGTGTATTTGTGTGTGCATTCAGGATCAGCTGGATGGCTCACTGCAGTACTGCTTGTCT GCAATATCCCCCAGTAGGACTAGACTTGATGAAGTTGAGTGGGGAATTCCTCATGGCAGT TTTCTTCTCTGCAGGCTTTCCCACAAAGCACCAAGGGCTATGTACCTTCTGGAGCCCCCC AAGCAACCCAGAACTTTCTTCCCTATAAGGGGTTGCTGGGCCTATTTTATCAACCTGCTA AAGCAGATGAAAGCTGGCTGCAGAGGATGTAGTCATCACATAGAAGTAAGCAACAAGGGA TAAAGAGGGTTAGTCCTAGACCAAGTGTGGTGGCTCAGGCCTGCAATCCCAGCACTTTGG GAGGCCAAGGTGGGTGGATCACTTGAGGTCACGAGTTCAAGATCAGCCTGGCCAACATGG TGAAAATGCTGTCTCTACTAAAGATACAAAATTAGCCAGGCGGGGTGGCATGAGTAATTC CAGCTACTCCGGTGGCTGAGGCAGGAAAATTGCTTGAACCCCCATGGGAGGTGGAGGGTG CAGTGAGCTGAGATCATTGTGTGACTGCCCTCCAGCCTGGGTGAGAGAGTGAGACTCCAT CTCATAAAAAAAAAAAAAAAAAAAGGTTTAGTCCTGGTTCTGCCACTTGCTACCAAAGTG ACCTTCGGCAGGGTAGCCTCTCCAGCTTCTATGTCCTGCATTATAAAACAGGGATAAGGA TCGAATGAATTAACACATGTGAAGTGCTTAGCACAGTGCTGGTACACAGGTGCTCAATAA ATATTACTTACTATAATTACGATTAGGATGAAATGCATTGTGTCAACAAATTCATCAAGA TAATTTCCCTTTCATCAAAGCAAGGCCAAAATTGGAGTGCTATCAGAATTCTAAAAATGC AGAGAGATAAACTCAGGCCAGGAGAAATAAACACACACCAAATATTCTAGATACTGAGGA ACAGAAAAGGGTATGGGTATTCCTACCCTTCAAGGATTTAGGGTTCAAAATGTTCATTAA GATGAATCTTATGAAGAACTTGGACAGGAACATTTAGACAAGAATGGCCTGAAGAGGCTA ACTTCATTCCCAATGGCTTGTCTGGATGGAGGCTGACAGGGTCAAGAGCTGGCAGAGCTT CCTGCTTGCACAGCCCCCAGCCCCTCTTGCTGAGTGTGGCCCATCCTCCAGCCTCAGTTT CCCTGGCTGGAGTAATAGCCCCCGGGGCAATGGAACATCTCGAAAAGAACCCAGGTGTGG AGCCAATCCTCTAGCTGTGTTCCAAACCCGGATGTCCCACCTACTATCTGTGTAGCTTCC AGCAGTTCCTTCACCTCTCTGCATCTGTTTTCTCACCTGTGTGATTAGGAAATCATGTGT GTGATGATAAAAGATGATGTAGATGAATATGTCCTGCACAGGGGCTGGCCCCCTGACAGC ATCCCTCCCTCCCACAAGCTGCCATCCCTCCATGAGGCAGAATGTATGCCTAGAAGGGTG ATGTAGGCACCAATAGAGGTGGCTGCGCCTGAAAGCACTGTGGGAACTCCCTGCTCCTGG CATTTGGAGATGAAATCTGAAAGGTCCCTGTTAGGCCTCCTTCAGGCTAGTGGGATGACC ACAGGCGTGAGGCAGTCCGCCCCCCCTGGTGGGAACAAATGGTGGGGCTGCCAGGTGGGA TCTAACCAGCCTGGACAAAAGGAAGCAGTGTGACCAAGCCATCTGTCTACACAGGGAAAG CAGAACCACAATAAGCTGTGTTAGTCTTAGGTAAGCCTAAGTGGGTCTTTCATGTTGTTA TTGGGTCAACTCTTGTTACTTTTAAGCAATTTCTGCTACTGTGTAGACCCAGTGGCTCCC ATCTGTAACCTCAAAAGAGTTTTGCAAGATTATTTTGGAAGGCCTAGGGATAGCTCATGT GGACCCTCCTACAACATTTCCCTTTCATCTTCCTTCGTGTTTTGCCACAGTGTGAGAATT TAACAAGAAAAAGCTGCTGAAGGAGAGTGACGGGATCAGGAGAGACAGAGAGAAGGGATT AGAGCTCCAGGTGGGAGTCAGAGTGCAAGGAATCAGGTTGGAGCTGCGGGACCTTGGCAC AATGCAGGCAAACTGGAAAATGAAGATGCATTTGATGGTCCCAAAGGTGACTTCAGTTTT TGATTCCAGGTGCCCAGGACAAAGGTACCAAGTCACCTCACACATCAGCCCATGAATATC AAGTCAAAAGAAAAAGGCACAGGAGTTTCTCTGGGGTGGCCTTCCTTCCAGCCCATATTG CCATAGGCCACCCTGATACCCTACCTCAACCCATTTTCCTTAAGTCCTAACAGATTCTAG GATGTGTCACGGGACTCTGAGACCCCCACTCCACCAGCTCAAACTCCGACAGGAAAGCAA AGGCCAAGATTTCCTATGAACAACACATCTCTATGTTTAAGGAGCTGTCTGCTGTGCCCC TGTCTGCTGTGACCTCATGAATGAGTGATCTGAAAATTGCTGTGACCTCATGAATGAGTG ATCTGAAAACGGTGCTGAGTCTTCTACTCCCCTGGGTGTAGGTGCCATACATCTCAAGAC TAACGAAAGTCAAATTTGGGCCATCAAATTTTGCTTTCAGTGAGGTCAAAGCAAAACTCC ATCGTTTCTTTGAAGGGCAATTGCAGTGATTGTAGTCTGTCACAGAAGAAGCAGTTCTCA GAACCACTGATCCTGACCAAAGACACGGCCAGAAATAAGTGCAGGGTAGACCCACATAAG TCTCTTTTCCTCAAGCAAGGATATGACTATGGAAAAATTTATTTTCATCATTCCTCGTTT CACACTTGGCATTTGAGCTTCATGGATGGCGGGAAGAAGAGAAGATGATGGACTTGAGAA AACACACAGCTTCATGAAGACCAGGGTCAGGAAACAAAAGGTTTCGATAAACAGGAGACA GCAAAGATAACAAAGGAACAGAAGAATCCGGAAGTTAAGAAAGTTTAAAAAGGAGAAAGA CATGTAAAAATTGGGAAGTTAGCTCTTAAGATAAGACAGAGAAGCCAGCTGATCTAGGGC AGGTGATAACGAGTACTGATAAAATGAAACTGCTACTTCCATAAAAAAAAAAATCCCAGC CCAGCTATAGTCCCAGCTACTCAGGAGGCTAAGGCAGGAGGATTGCCTGAGCCCAGGAGT TCGAGACCAGCCTGGGCAACATAGTGAGACCCCTCATCTCTTAAAAAAAAATTCTGAATC AAATTGTAGGCCTCATTTAGTTTTTTGAGAAATCTTCCAAAGGAGAAGTCACTATATCAA AAAGACACCTAACGTGCATGTTTATCACAGCACCATTCACAATTGCAAAGATATGGAATC CACCTAAGTACCTATCAACCGATGAGTGGATAAAGAAAATGTGGTAAACATACACAATGA AATACTACTCAGCTGTACAAAAAGAATGCAATAATGTCTTTTGCAGCAACTTGGATGGAA TTGGAGGCCATTACCCTAAGGAAAGTAATCAGGAACAAAAAACCAAATACCATATGTTCT CACTTATAAATGGGAGCTAAGCTTTGGGTACACAGAGGCATACAGAGTGGTATAATGAAC ATTGAAGACGCAGAAGGGGAGAGGGTGGGAGGAGCATGGGGGATGAAAAGTCACCTATTC AGTATGATGTAAACTATTTAGCTGATGGGTACAATAAAAGCCCAGACTTAACCACTATGC AATTCATCCATGTAACCAAAAACCACTTGTACCCCTAAAGCTGCTGAAATAAAACAATTG TTTTTAATTTAAAAAATTCCATGCTCTGGAAATTCTAGGACAGGAGAGCCAATCAGGCAC TGTTCAGAGCAAGCAAAGAGCACTCACTTGCTAACTATACCCCCTCCCTGCTGTCCCCTG TGCTCCTTGGCTGGCCAGGGACCTTACCAACAGAGCTGGACAGCACCCCCAGCCTCTCCC AGCTCACCTTATCTCATCAATCAAAACTTACTCTGTGTCTCATTTTTTAAATTAAATAAC CTTGGGCTATAATGGGTTAATTAGTTAATCAAATCTATTCTAATTCACTGATTGGCTCAT ATGTCATCTATTTGAGAAAATTGTATATTAATAGCCACTTCTTGGCTGTTTGACAACTGC TGAGTCATTTAGTATCTCAGGACCTCCATTTTCTTACATTAAAATAATGGGGGGGAAATT AATAACTATGAAAGGGTTGATATTTGAGTTGAGTCTTGGAGTAAAATGGAGTGGGAGGGC TACAGCATGCTGTTTTTAAGATAAGGCAAAAGAGGAGAAAGCATAGTTAAAGGAAATGAA TGTAGCAGCAAAATCGCCTGATGGACTCCTAGCTGAGTATAATTATTGCTGCATCCTCAA GGGATAAAAAAGAGCCATGCAAAATGTCCCAGAGGGGCTTGGACTTCCTATTACGTTTAT TAATCATCTTGATGAAAATGGAAAGTCTACATTGATTAAATTCACTAATGATCCTAAACT GAGCAGAGGAGTAAATTCCAGAAAGGATGGATTTATAAGGTGAGTAGTAATATTAATCAG CTCATCTTCATGAAAAGGATGGCAGTAAATGAAATGGGATTTGCTATAGATAATGGCAAC GAGGTACACCTGGGGGAAAACTATAATGAGCCCAGATTCAAACTAGGAAGGTGTTATTTA GGAAATAATAATGGTAAGAGAGCTCTAAAGTGGAGAGTGAATAATAAATTAAAAACAAGC TTAAAATAAGCGCTCGTTATGGATCACAATTTCACTCTCAGCACTTTTGCAGTGGGGTGG TGCAGAGGAGGTGAATGTGAATGGCAGAGGTGGAAGCAGGTTTGTAGTGCAGCACTTATA TTTTACAGGTGAGGATGCTAAGCCCAGAGAGGTTAGGTGTAGACTGACTAGGCCAGGGTG GAAAAACCCTGTCATGCTCGTCACCACTCTGTCCCTTGCAGTGGTGGCAGGAGATCACGA TTCCTTCTGACAATCTAAATTTAGCCTCAGAATCCTCAATGCTGCACTCTAAGCAGTCTC TGATTACTTTGCTCACAAAACATTACCTTTTGTCATCTCTAGCTTATAACATAGAGCTAG ATGTTGGCAGAGCCGTAGCTAAAAACCTAGATGTCCTGAATATCTAGTGCTTCTTTTTCA CCTAATACGTTCTAAATTCTCTACAGTCAACATTGACTATGACTTCAAAAGTCAAAGACT CAGAAAGCATAACTAACTTCTTATCTAGGATTCTGACCTTGGTATCCATCATCTTGGTTT AAGTTTCCTTAGACAGCATTTTAAAATCTCCAAAATTGAATACATATAGAGAGAGGTGTT GGGAAGACACTTAGAAATAGCAATAGTTTTGAGCCAGTGAGTTTTGTGCCCCTGGGGAGT AACATAAAGCATTTTTAAAAAGAAGTCTATTGAATTCAAGTAACAAAAATTAAACTTCCA CCTTAGGCATTTGACAAAATTAATGACCTTGTTAAAAATTCCCTGAGACTGATTAATGCT TCTCGTATTTGTTTCCCTCCTGGGGAACAGAGTGAATTTTCCTGGTGCAAATGGAGCCAT GTCGAGGAAAGTCCTGTGTGTGCTGGGTCAGTTTAGTTAGGTGGGGGCATCAACCTAGGG AGGAGGGGAGGGAGGGGAAGATTGGTCTCAACAGAATTATGAAGCAGGTGAGTTTAGCCC ATTCTCACTTCCTTTTAGTGTCCTTTCAGTTCCCTCTCCCCAGGAAGGCTCATGCTGCTC CTGTAAGTCTCTCTGAGTGATGTGAGGGCTACCCCTGTAAGGCTGAGCTGGTTGTGTGTT GCACAACTTTAGGGGACGCTATTCTCCCTTGGGAACTCGGTAACTTAGCACGACCAGCCC CCTGGCAGATTCAGAACAGTTCTCCATTTATTAGGCCTTTCCTTATCTTTCCCAGTCTTC AGTGGAAATCTACCTGCTGTGTGTCAGATCGGAGTCATTTTCACATGGGCTGATGGGTCA CTGCCCGAGACTTTCCTGAAGACCTACCCCATAGCTTAAGCGAATGAATTAAATAGTAGA ACATTTTGGCATGTGCCTGAACTAAATCTCTCCTATGTATACTCTTCCAATGGTTGATGA ATACCTCATAGGATTCATGAGAGATGGCATCCACATGCTTGATCACCCATAATCACAAAG GTTGGCTACCAAGATGTCTTTTTTTTTTTTTGAGATGTCGCCCAGGCTGGAGTACAGTGG CGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCCCG AGTAGCTGGGACTACAGGCGCGCACCACCACGCCCAGCTAATTTTTTGTATTTTTAGTAG AGACAAGTTTCACCATGTTAGCCAGGATGGTGTCGATCTCCTGATCTGCCCACCTCGGCC TCCCAAAGTGCTGGGATTACTGGTGTGAGCCACCGCACCCATCCCCAAGATCTCTTAAAT AAGACTTTAATCTACCCAGCACTTTAAAGCTTGCAGAATCCTGTCCCACCATGCCAGAGT GTCCAGAGATCAAGTGCTAGAGTCAGTTAATCTGGGGTTAGAGCCCCATCCCTGCCACTT GTTGGCCATGCAGAACAGAGTTAAGCCAATTACCTAAACTTTCCAAACAAGTTTTTTGAT AGGACTAAGATTATGTATTTAGCATAGTGCTTGGCAAAATAAATAAAAATTAAAAAACAC ATGTAATCTGCTATCCCTGCTGTTGTTTTTATTTCAGATACGGTGTGGGGCAGGAAAGCT GGATGTTATCTCCTTTATCTTGAGAACCCTAGGAAACAGAGAGAAATTATTTGTCTGGGG ATACACAATCAATCCTTGTAAAGGCTGAATGTTAAACCTGGGCTTTCTATGTAAGGCTCC AGTCTTCTTCCCACCATCCCATGCTCTTATAGACCTAGTGCAACAGTTAACGACGTGTGT GTGCCTCCCCAGGCTGAATGGTTTATCATACACATGAGACGCACTAGTTGCTTTTTAACT GTTTCCTTCTCTCATACAATGCCTATGTTGACTTGCCGGAAACACCTGGATAATAGCAAA CACAGGGTTTGAATTTTCTTTTTTTTTTTTTTCTTTTCTTTCTTTTTTTTTTTTTTGAGA TGGAGTCTCACTCTATTGCCCGGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAG CTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACA GGCGCCCGCCACCACGCCCGGCTAATTTTTTGTTGTTGTATTTTTTAGTAGAGACAGGGT TTCACCATGTTACCGAGGATGGTCTCGATCTCCTGACCTCGTGATCTGCCCATCTCGGCC TCCCAAAGTGCTGGGATTACAGGAGTGAGCCACCACGCCCGGCCAACACAGGGTATGAAT TTTCTATCTTCAAGGTGCAATACCACATGTCCTGGGTGTGGAATTGACATCTGTGTCAGG GTAAGACTGGAAATGTGCCCCTTCATCCATAGCTGCCATTGGGTATATTATTATCCTTCA TGGATCTCACTGACAGAGACGATGCCCATCTTACTTGCCAAGCAAACTAGTCCATTTGAT CGTAACATAAACAGTTGCAGAGCTAACACAGGAGTCCCGGTGATGCATGGACCTCTTTAT ACTCTATATCTGCTAGGCTGAAGGCTCAGGGACAGATCCAGATTTTGTGGGACCCTATAG ATTACACAGTTTTGGAATCTTCTTTTTTTAAAAAAGTATAAAGTCAAAATTAGGTATGGG AAAATCGAAGAGATGGAGAACAGACTACTCGTTGCCAGAGTTCAGGGATAGAAGAGAGGA GAGAGAGATGGGTGTATTTATAAAAGTGTAACAAGTGATGATGCAACTGCTCTGTATCTT GACTGTGGTGATGGGTACATGAACTTAAACATGTGCTAAAATTGCATAGAACCAAACAGA CACATACAAATGAGGACATATGGCTCGGCACAGCGGCTCATGCCTGTAATCCCAGCACTT TGGGAGGCTGAGGCCGGTGGATCACCTGAAGTCAGGAGTTCGAGACCAGCCTGACCAACG TGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCATGTGCCT GCAGTCCCAGCTACACGGGAGGCTGAGACAGGAGAATCGCTCGAACCCAGGAGGCAGAGG TTGCAGTAAGCTGAGATGGCGCCACTGCACTCCAGCCAGGGCGACAGAGCAAGACTCTGT CCAAAAAGAAACAAAAAAACAAACAAACAAATGAGGACATATAAAATTGATGAAATCAGT AAGATCTGGATTACCAACACCAATATTCTATTCCACTATTGTACTATAGTTTTGTAAGAT GTTACCCTTGAGGAAAACTGGATGAAAGAGACACAGGATCTCTATTATTTCTTCCCACAG CTTGTGAGTGTGATAATTATTTCAAAATAAAAAGTTTAATTTAAAAAATGGATAGAAGTA GAAACAAAACTTGGAAAAAAAACAGGCACCAGGTCTAGGAGAGTTGGCGCTAATGAGAAG CCTAGACACTTAAAAACTTCACTGGCTTCATGGCAAATCTATTCCTGATTGAAAAGGCAG TAGACCGAGAGAAAATTAGTCACAATAGAGATATGAAACCATTTTAAGACCCACGAGTGA ACGGGTACGTTTCTGGGATTACCTTTTTTGATCACAAGGAAGGCTGCCAATGTAAAATAA ACATAAGCTACTTACCCACATAAATAGGTTGGCTCCACTCACTCCAGAGCCCTGCCTCTC TGCACATGGAGCTCACTGCTGCTCTCACTTGAACATCGTACTTAGAAAGATCATCAATTA TTGAGATGAATGCATTGGTCATCAATTTTTCTATCTAAGTGGGGAAAGATAGCATTAGAA GAATCTCTAGACACCTAATTTAGTTCTGCCGATTATCAGAATGGGAGGTCCTATATAGGT CATGTGACTCACTGTTCAGCAAGTCCTTTAAAATCAACAGGGCACACATTAATTCGTTTA TGCTAGGTGCGTTAGTGTGGATGTGTTGGCAGTCACCCTTCAGTGGAACGCTATCTTGTA ACCAAAATATACGAAATGATCAACGGTCAAGATCCAGGTGTTCCTATCCAGGCCCAGCTG ATGTTTCCAGACTGAAAGACTGGAGTGGCCTATGCTAGAATGCATTATTCCCTCACCTTG TCTCTCCATAATCTATAGTCACATTACTAAATAATGTCACATGAACGCTAGATTGTCTAG TGTTGAAATGAAGCTATTTTCTCATGAATGAGCCCTTCTTCTTTTTCCTTCTACTGATCA TGGTCGCCACCATCCAGCTAGTCCCCTGTACCAGAGATGTGCTCCTGACACCTGTATCTT GAATACCCCCGGAGGTGTTTCTCCCTTTTTTACTCCAGCCCTGTGACCATTGCCTATTTT AGCTCTTATTATCTTTTGCTTGGACCTTTGCAGTAGCCGCTAACTGATATCATATGTCCA TGTCGCCCCTCCCCACTCACATCCAGTTTTCATGCTGCTACCAAAAATCTTCTTTTACTC TGCAAATGTAGACATATTTCTCTATTGTGTAAAACTCTTCAGTGGCATCCATTGCCCAGA GTCATGGTTTTTAAAAAAGAAGCCACTTCTTTATTTTTTAGCAAAATCTTATAGAGCCAC TCTGGGAGAAATCACAATGTCAGATACAGAGTCATGATTTCAGCATTGGTCTTATGTCCA GGCATCCAGGCAGACTGAATTACTTGCCACTTGACTGAAAGAACCATACTCTCTCAAGCA TAAAGTTACTCCTTTTCCTAGGCTGGTGCAAGTCAGGAACTATTTATTACTGGCTTGTGA TGGGCTAAATACAGATAAAATTATGACTGCAATTTGGAAGTTTTGATAGCAATTTGACAT TGCCATGATATCCAAACACATGATCAGTGAACTGACACTTTACATGTCTTTGGCTATATT TAATTTTTTCTAGCAGATCATTTTTATTGTATTTGACAAAAGCACCAATCTATGGTAGAT TAGACATTATAAAAACACACGCACACACACGTGCACACACAGTCCTTCAGTGTAAGTATT TTGGGAAGCTCTGGCTAAGAAAGTCCTTCTCATGTTTTCTCACCAGACTAGTTTCTCTTC ATCCTTACAGATTCCGTTCAATTCCTCTCTGCAGAGCAGGCTCTGTGCCCACACCCCCAT CTCTAGCTGTACTGGCTTTTCCTGTGGGAGGGCAACCCCAAGGCTGGGCAAGTATGTCAC AAGATTGGGTCACTCCATGGCAGAAACAGTCTTATTTCTCACAAAGAAGCCAATTTGTAA ATATTTGTTGAATCTAATTGAATTGGCTTTGTCTACTCTCTGTAAGACATAAGTTGGAAT CCTATTTTTTTTCCTAGCTTTGTGACTGTGGGAGAGTTACTTCATCTCTTTTGCCTCACT TTCCTATAAAATGGGAATGGTAATTACATCATAGAATTATGTGAGGATGGAATAAACACA TAATAAAGCTTGACACATAATTGATGCTCAAGAAATGTTGATTGGCTTTCTTCTCAGTTC CTTTCCCCTTGAAATTTTTGTCTATTAGTGCTAATGAGTTTTTTTAATTGTAAAATACAT ATAATGAAATTTACCATCTTAATCCTTTTTAAGTGTACAGCTTTGTGATATTAAATAGTT TCACATTGTTGTGTCACCAATGTTCAACACTCTTTTAATCTTGCAAAACTGGAACTCTGT ACCCATTAAACAATACCTCTCCTTCCACCCTCCTACCAATTCCTGGTAACCACCATCCTA CCCTGTTTCTATGAGTTTGACTATTTAACCTCATAAAAGTAGAATCAGACAGTATTTGTC CTTTCGTGACTGACTTATTTTGCTTAGCATAATGTCCTCAAGGCTCCTCCATGTGGTAGC ATGTGTCAGAATCTCCTTCCTTTTAATGCTGGATAATATCCTATTATATGTATATGCTGC ATTTTGCTTATCCATTCATTTAATGGGCACTTGGGTTGCTTCCAGCTTTTGGCTATTGTG AATAATGCTGCTATGGACATGGGTGTACAAACATCTCTTTGAATCCTTGCTTTCGATTCT TTTGTATATGTAATCAGCAGTGGAATTGTTGGATCGTATGGGAATTCTATTTCTAATTTT TTGAGAATTCATCATATCGTTTTTATAGTAGCTGCATTATTTTAGTTTTTTGTTTTTTTG TTTTTGTTTTTTTAGATGAAATGTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCAT CTCAGCTTACTGCAACCTCCGCCTCCCTGGTTGAAGTGATTCTCCTGCCTCAGCCCCTGC CCCCGAGTAGCTGGGATTATAGTCACGCGCCATCACGTTGGCTGATTTTTGTATTTTTAG TAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGGTCTCAGGTGATC CACCCACATTGGCCTCCCAAAGTGCTAGGATTACAGGCGTGAGTCACCCCACCCGTCTAT CATTTTAGATTTTAACCAGCACTAGTACCAATGAGTCTGTATCTAATCCTTTGTATTAGT TTCAACCAAAAGTATGTTCTTTCAAAACAAAAGGCCAGTAAGATTTGGTTTATATCTATT TGGTTATATCTATAATACCTGGGTAGATTAAGTTAACTTTGACCTTGTTAGTACCAAGCT GTAACTTGGTTGCAGTCACTGAAGATAATTTTTTAAATGTTTCTAAAACAAATGTCTGTT ATCAAATATTGGAATAATCTGAGTAATTACCTGCAAATATCCATTCCTTGTATTGTGTAT TTTTACTTCATAATCAAAGCAATGGATTGGAAAAGCAGACACTGGTTTCTCCCATTGGAT AGAGAGACGAGTTCCTTCAATCTCTGCTGTGACATTCAGTGGAGGATTTATTTGATCTAA GTTAGGGAACGAAAGATCAGTGATTTTTTTTTTAGAATCAGTGATCAAAGCTGATAATTC CAATCCACCCACACTTCTCAAGGCATTTCTAAGATACGCTTTTTTCAAATATTTACCATC AGGTCTTAATCAACTGATCTCCAAGCCACAGGAAGCCGGTGGCCTCCCATAATACTCTTG TCTTATAGTGCTGAAGAAGAAGAGACCCTTTCTGGAAACTACAAGGATTACTACTCCAAA TAGAGTTGAATGCTTGAATTACTTCCCCCCCTCAGCTCATTGCAAGACTCACCCACCATC CCCCTTTACTACTCAAGTTGTACCAGGCCCAGAATAAACCTGACCACTGAGAGAACATTT CCCTGGACCTTCCACCAAGCCTTGCCTCTTCCCAGTAGGTATGTGGCCCTGAACAAATCA CTTCCCCTTTCTGAGATTCAGTTTTTAATTTTAATTTCATTTTGTTTACTGCGTCTTTTG GTTTTTGTTTGTTTGGGGGCTGGAGCAGGAAGCTTCAGTTTTCTTTTGCATCAAAAAGAA TGGATTGGGGCAGGGCGTGGGGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGG CGGGTGGATCACGAGGTCAGGAGATCGAAACCATCCTGGCTAACGTGGTGAAACCCCCTC TCTACTAAAAATACAAAAAATTAGCTGAGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTAC TCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGCAGGCGGAGCTTGCAGTGAGCCGA GATCGCGCCACTGCACTCCAACCTGGGTGACAGAGCAAGAAATCTGTCTCAAAAAAAAAA AAAGAAGAAGAAGAAGAAGAAGAGTGGATTGGGCTAAATTTGTCTTTACTTAGGACTCTA ATGTCCTTTCCCTTGAGATCTCACTTGATTGTCTTATGGTCCGGTGAGGTGAGGGGAAAT GAATTCTTAATGAGTGTCCTTGTCTTAGGTAATATGACTTAGATCTCACAATTAATAGGG AAAAGCTAGGAGTGGGATCCACTGGCTTCAGAGCCTCCTATACCCTATGAAGAAAATTCT TAACCAAGAAAGTACTTATTTATTTTAGTAATCCTAGGAATCAGCCTCAATAAAATGAAA ATCATAAAAGAAAAATGAATTCCTGTGGTCTGTACTAGATCATATCCATTTTCATATTAA TATCATTGTTTCCTAGGTCTTCCTCGGCATCTTTTATTGCCTATTTTCATGAAAGTGACA TTTTTAGTTCACCTAAGAAATATATTACTGGAGAGAATTGCATAACCTCTTTAGTAAGGG CTATGATTCTTTACACAAAGTTATATTCCATTGGATATAGATATGTCACAGCCAAATCAT ACCTTCTAAATAATATTGTAGTGTATTTATTAAACCTTTATGCCAGGCACTGTTCTAAGT GCTTTATCATTAGTAACACAATTCTCACGAAGACTGCACAGGAAGTATTGATTCCTCTCC ATTGTTTCAGATAAGAAGATTAGGCACAAAGGAATGATCAGCTTGTCCAAGGTCACTCAG CCAGTGGTGGAGCCAGGATCCAAATCCAGGCAGTCTGGCCCCACAGCCCATAATAACCAC CCACCATTGAAATCTGGAATCTCCATAACTAAGAATGCCATGTGAGAGCGCCTGATGAGT TTCACTAATAGAACTATCTGGGATGAGGGAGAGTGTCTTCTCTATTGAGAACTGAGCAGA CAAAACCACGAATAGAATTTTTAGAGCTGAGAATTGCACACTGAGAGATATTCGAGCTGC AGAACATCCAGGAGATGGGCCAGAACAGTGAGAAATTCAGAGAGAGAGAGATGTTAGCCT GGGAGAAGAAGGGCTTCTGGATGGGAAACGTGCTGCCTGTGAACAGCTAAGAGAGGCTAT TCTATAGGGAAGGGACTCAAATCACCTGGGGTGGCACTAGTCCATCACAGGACCCAGGGG CAGAAATTTCACAAAACCTGTCAGAACTCATGAAGGATTAAATGGTCTCTTTTAAGCAGC TAAATTCACTTTTTCTGGTGCAGTGATTCTCAACTGGGGGAAATTTTACCCCTTGAGGGG CATTTGGCAAAGTCTGAGACTTTTTTAAAAGTCACAGCTCAAGGACAGAGGGGCATACTA CTGGCATCTAGTGTGTAGAGGCCAGAGATGCCGCTAAATATCCTACAGTGCCCAGCACAG CCCTCCATAACACAGAGTTGTCCAGCAAAACTCACTGGTGGTGTTGGAATGGAGAACCTT GCCCCAGTGGTTTTCAAACATGGGTCTGATGCTTACTTGGCATCAGAGAAGCAGTAAAAC TAGGTGATCTTTATAACCCTTCCTTCCAGTGCTGAGATTCCGAGATTCAGTTATTTCAGC TTTGGGTTAAGTCGGTCTTACCAATGGCGTGAAGGGCAAACAGCTGATCAAAGGGCCTGA TAGCAGAGTGCTTGCTGGAGCCGTTAACAAGCACCGCAAGCCAGTCACGCCCTTTGCTGA GGATAAAAGTCCTGGGAAACCAGCATGCGATATTTCTCCCCAGTGTGTCTTTGCTGTATT CTTGGCATTCTTCAGTCCAAGAGCCATACCTAAATTGGAACATTTACGAGTGTTATGAGG TTGCAGGAAACAACCATTTGCCTAAGTAAAAATAGGTACAGTACTAACCTATAGTAGAGA AAATACTGCGTGTCCTCAGGGGCATCTGTGCCAACAAGCCAGGTGCAGTGAAGGGAAACT TGGTATGACCTTAAACGTGAATAATTGTCTTCTGTAGTGTTTGTGGTGCAAGTTAAATTC ACAATTGAGGTTCCAGGAGACCCTAGGTAGTCAAAAGTAAAAAGGACAAAACATTGCCAT GGCAAACTCTGAATTTCATGCTTCTTTTGGAACTATAGTGATGTGAACGTCGTATTCATC ACCAAAAAATAATCATCTTCACATTTTTTTTTCCCTTGAGACAGAGCCTCACTCTGTCAC CCAGGCTGCAGTGCAGTGTTGCGATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTTGGA GCGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGAGATGACAGGTGTGTACCACCACACCT GGCTAATTTTTGTATTTTCAGTAGAGCTGGCGTTTCACCATGATGGCCAGGCTGGTCTTG AACTCCTGACCTCAAGTGATCCACCCACAGCCTCCTAAAGTGCTGGAATTACAGGCATGA GCCACCATGCCCGGCCATGATCACATATTTCTAGAAACCTACTAACTACAAAAGGCCAAC TTACTGGAGATATGGAATTAGAATTATAAAGTCCCCATTTCTGATATTCGAGAGCTTCCC AGCTATTTTGTTTGGGGCCTGGGGGTGGTGTTTGTGCAATACATGTGTGGAAGTTCAAGA GAAGTACAATATATTGTCATTTTGAGGTTGATGTCCGGCAACTTTGGTGCTCTAATGCCA CATTTGTTAATAACTAGCTGTGAGACATTGACCCCCACTCTTCTGGGCTCTGTGTTTTCA ACTGTAAAGGAGCGGGTTGGTACAGGAAGGTCTTGCGTATCCCTTTCCATCCTAGAATTG TGTGATTCATTAGGTTGTATCCAAATTCTTCATGAATTACATAGGTTGCTGCTCAGAAGA AATGAGTTTTGACAACACTGCAAGATTGCAGACTTTGCAGACTTGATGCACATTAGCATG TTAAAGTCCTCTTTAATATACTAGGACTTGAAGAAAACCTTGAATTGGCCAGGCACGGTG CTCATGCCTGTAATCCCAGTGCTCTGGGAGGCCAAGGCGGGTGGATATCTCTTGAGCCCA GGAGTTTGAGACCAGCCCAGGCAACATGGTGAAACCTCGTCTTTGCAAAAAATATAAAAA TTAGGTGTGGTGGCATGCACCTGTAGTCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATT GTTTGAGCTCAGGAGTTTGAAACAAGACTGGGCAACATGGCAAAACCCCAACTCTACAAA AAATACAAAAATTAGCCAGGTGTGGCGGCATGTGCCTATAGTTCCAGCTACTCGGGAGGT TGAGGTGGGAGGATCACTTGAGCTGGGGAGGTCGAGGCTGCAATGAACCAAGATCATACC ACTACACTCCAGCCTGGGCAACAGAGTGAGACCCTGTCTCAAAAAACAAAACCTTCAGAT TTTATTTTATTTATTATTATTATTATTATTATTATTATTTGGAAACAGAGTCATTCTGTC ACCCAGGCTAGAGTGCAGTGGCATGATCTCAGCTCACTGCAACCTCACCCTCCCGGGTTC AAGCAGTTCTCCTGCCTCAGCCTCCCGAGTAACTGGGATTACAGGCACGTGCCACCACAC TCAGCTAATTTTTGTATATTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCT CGAACACTTAACCTCAAGTGATCTACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGG CGTGAGCGACCGCACCCGGCCAAGATTTTAAATGCAACCTTTTTATGTTTGCTTCATTAA GGATTTCTCAAATTATGTGACTAGAAAGGCTTGTTTTCATTTCAACCTCTCGTTGCTGTA TTAACTGTTGGTCTTTAAAATACACTGTGGGAAACACTGGCCTTGTTGGTGGTTGCTCAG AGAAGGAAACAAGCTCTTGCACCTGGGCCAGGAAGGACCGCATTCAAGTGGGAGCCTTGA GAGATAGAAGGGGGTCTTTTGATCGTAGCTTAAGTGAGCTGTAGATCATTTTTATCACTG TCAGCCAGTGTCTTTCAAGAAGCAGAGGGAGAAGATGATGAGAGAGAGCCTCTTATTACC TGTAGAGAAGTTAAAGATGGATTTCTTCTTCATATCTGTGCTTTTGCACAGACAAAAAGA AGAACTACCTCAAAGCAAATTGACTTATTCAGTTCATGTATATATGCATATATTAGGTTG ATGTAAAAGTAATTGTGATTTTGGTCATTACTTTTGCACCAACCTAATATATATTTGTCC ATGCATTAAATGACCAGAAAGTCCACACCCAAGTACACTTTAGAGATCCTGACAACTCTT TGTCTTATAGTTCTCATCCAAAGAATCATTTAAGTGAATTCCACTTGGTTCAAAACAGAA ATAATTTTTATTAGTGTCATCCTGTATCAGAGTGTTCAGAGGATAATTAGAATTGTAGAA ATGTAAGCTGCAAAGTGCCTCATAGGTAAAATCCAGTTGTTCATTATAGAAAGGAGGAAT GGTGGTTTGACGTAAGCCACATACAATAACCCATCTCTGTGTTCCTGTATCTACCTTGGA TTAGTCTCTGTACTTGGGATCAAGCCCATGCAAATTGGCTGGTATGTGGTCTAGACAAGT TATAACAAGTAAATGGGGCCGGACACGGTGGCTCATGTCTGTAACCCCAGCACTTTGGGA GGCCGAGGCGGGTGGATGGCTGGAGGCCAGGAGATCGAGACCAGCCTGGCCAACATGGCA AAACCCCATCTCAATAATAATAATAATAATAATAATAATAATAATAATAATAATACAAAA ATTAGTCCAGCATGGAGGCGCATGCCTATAATCCCAGCTACTCGGGAGGCTGTGACATGA GAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGTCAAGAACACACCACTGCACTTC AGCCTGGGCAACAGAAGGAGATTCTATCTCAAAAAAAAAAAAAAAAAGTAAATGAGAAGA TCTTTATGTTTCTGTTTTAAGTCACTGACACAATTCAGGAGGTATGGTCTTTTCAGCTGG TGATATGACAAAATAGTCGTTTGAAAATTACCCGTGAGCTCAACTGACCAAGACAATGGT TATTGGGTGCACCCACATGTCCCAGGACTTGGTAGCCTGCTTCTCCTCTTTTCTCTCCCC TGTTGTGTGTGCACTTAAGTGTTTGATCAGAAGTATTACTGACTCTAAGTATCAGAAACA CCAACTTTCCACTGGAGGCCAATGCAGAGACAGTGGATATTTCTGCAAGAATGTGCCAGA TGGAATTCAGTTGGTTATGATAAGAAGTGGCAGCAGCCTTGGTTAGGATGTTGTTGATAT GGGAGAGTACTTGAGAAGAACGGGTGACTGACTAAAGAAAAGTGGGTTAGTGTTAATTTT TCTACTTTTCCATATTTGCAAAGTCCAAAACATACAAACTGGACTTTTGGAGGCCTGCTT TACCTGGTGGGGCATGAAGTTCAGCAGAAGCCCAGCTGCTGGCCAGTAGTGAGTGGTCGT TCTGCAGGATGGTCCGCACACTTGCTGAAAAGCCTTTGTGGAGGATGGTTACACATTTGC TTTCAGTGATTCTGGTTTCATACTAAAAATAAAACCCACAAGTCATGATACATAAAAGAG AACTAGACTTAAGAGAGCTATTTTAATCAAATATGCATTTTCTTCTACTTTTTAAATGAT TAGTAAGATGCAATGAAATAGTTTTGCTAGAAAAAAAGTCAAAACAAAACCATTGTAATA ACAACATAGTAATTTCTCAATGACACATGAACGCATTATTCTTGTAAATACAAGCGAAAT ATTACAGTTAAACTCAAGTTCCCTTTGAGCACCATCTCCCCAGAGGTCAATGTCGGACAG AAAATTCTCTAGAATTCCATATTGACTGAAAAATAGTGAATATGAATCACTTCTCCCTTT GTTTGACTTTATTGCACACCTAATATGTAGCAGGTGCCTGAATGTAGCCCCGAGGTAAAA CTGAGGCTCTGAGAAGCTAAATGACTTGTCCCAGGTTGCAAAGGCAGGAAGTGGAAGAAC TGGGTTTTGAACTTAGTTTCCCTGACTCTCCACTCTGCCTGCTCACTTCTTGTTTTACTA GGCTACTGTCTCCTGTTCTGTTGGTAATTTTATGGGAAACAGAAAACCAGTACCCAATCC ATGGTGCCTAAAAAGTTACTAAACATTCTTCCTTAAGGGAAAGAATCATCCAAAAGTTAA AATATTCTGTGATGCTGTTTAACGCTGAACAATACACCCGGCGCTAGCTCACAGGCATTC TTAGAGAGACACTATTCTACTGGTAACATAACATAGAGCCTGTCAGTAATTTTATTTTTT TAATCCAAAATTTTATTTGATAAAGAAAATGCAGTCAAAATGCATATTTATTCTCAATAA GGATATCCATTAGAATAAACACTTACGTCATCTTCTTTTGGAGCGTTTATTTTCACTTGA TATTCTAGATTAACATTCCTTTGCTCTTGATCAGGATTTGGTTTCCATTGTAAAAGAACT TGAGCCAAACCAGTAACTTTAATGGTGAAATTGACAGGTGGGAGAAGTGAAACTGTTGAT TCAAAGAATAAAGAAACAACACAATGTTCAACTGGACATAGGCAGCACTTTTAAAACTTT TCGAATATTTATTGCCCTGCAGATGCTGTCCTGGACCTGCCAGCACCACAGACACAGTTG CTCCTGCGTGCCTGTAACACCGGGGCAAAGAGAAAGTGGCTATTTCTACCCGAGTAGCTG GGACTACAGGCGCATGCCACCATGCTGGGCTAATGTGGGTTTTTTGGTATTTTTAATAGA GACAGGGTTTCACCATGTTGGCTAGGCTGGTCTTGAACTCCTAACTTCAAATGATCTGTC CGCCTCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCACGCCTGTCCTAGAAG AGGTTTCTTCAAAACTGTTTTTAATATCTTTTTTACGTTGCCCATGTCCAGGTGTTTACC TATAATACCTATATTTTTATTGAAATATGAACATGTTACTATATCACTATTCACTATAAC CATAATTTTCAAACTGAGAGTCATTATCCATTAACAGGCAATAATAACAATGTATTGGTT TGTGACCAGAATTTTTGTTTTAGTAATGTGGAAGAAAAATAGAATAGAAAATATCAGTGT GCATCAAACATAATAAGAGCTGTTTCATGAATCTCGTTTCCACTACATAAAGGTAGTTAT ATATTTGTATGTGTGCTGGTACATAATGTAAAAATGTATTTACCTCTTATTATGAGTCAC AGACAAAAATATTTGCAAGCAAACTTACTTAAATAGGGCTTTACAGAAAGAAAAGGTTTC TTCCCCCTGCATGAGCCATTCTCTGACTTTGCTTTCAAAATTAAAGCTTTTGTTTAATTA CAAAATCAATATCTGTTTATTGAAGAAATTTTGGAAAACACAGATAAGCAGAAAGAAGAA AATAAATTTTTTAAAATAATTGTACCACTAAGAATGGAATTAACATATGATATATTCGTT ATGTTTTTTTCTGGGCGTATATTTATGCAATTTTTAATTTTTTTTACCACAATTAGGACG GTATTGTACACACAACTACAAAACCTTCTTTTATTCATTTACTAAGTTATCAGGATTTAT CCATTGACCTTAACGGACTTCCACACCTCTACATCCATGTTTACCACATGAGGACTTTTA GAGCTCTGTCTATATTGCATTGTCCATTACGGTAGCCACTGGCAACTTGTGGCTATTGAA ATTTTATTTAATTAATCAATTAATTTTTGAGACAGAGTCTCACTCTGTTGCCCAGGCTGG AGGGCAGTGTTGTGCGATCTCAGCTTATTGCAACCTCTGCCTCTCAGCTCAAGCTATTCT CCTGCTTCAACTTCCCAAGTAGCTGAGATTACAGGCATGTGCCACCACACCTGGCTATTT TTGAATTTTTAGTAGAGTTGGGGTTTCACCATGTTAGCCAGGTGGGTCTCAAACTTCTGA CTTCAAGTGATCCACCTGCCCCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACT GCATACGGCCTAAACTAATTTAAATTCATTACCTTAGTTGCACTATCCATATTTCAAGGG CGCAATAGTCACATATGGCTAGTGGCTACTGCATTGGACATTAGAGAGATACAACATTGT CATTACCATAGATAGTTCTGTTGACAATGCTAGACTGGGACCATGTGATGATTTTCCTTA AACTCTGTCATCACATCAAATACATAACATCAGCAGATTTCAGGACAAAATGCAGTGGAA GTTTCTTAACGTTTGGTCATGGGGCCTTCTAACTACTCCCTTGTGTGAGAAGACATTCCA AATGCGACCACTGGCGCCAGCTTTATTCCATGGTGCCCGGACACCCACACTTTGACTTTG ATTTCCCACTGTAGCATAACATTTGCATTTCAGCCAACATTGCTTTCTTAAAATATGGCA TGTTTAAAGCATCTGTCTTCTGATGGGGATAAATATTGTCTCATAAAAATCCATATATAA TGTTCTAATCGACAGTTTAAGAGGAAATAATGTTATCCTTTTACTAACATATTTTTAAAA ATAAACATTATTGAATTGAATAGAAGGTCCTTACTCTTTTCATCAGGAAGTAAGTCAGCT TGCAGTATCTCAGTGGCCCCCAAAAGGATGAGTAATACATGCGCCACGATGATCATATCC TACAGAAAACAAGGGAGATACCAAAATCATCTTGTTGCTATTTTTAAGAAAAACTGATAG CTGCTTTCTAACATAAAATGCAGTCGTTTGGCCATTTAACAGACATTTATGGCATATTTG TTATGCGCAAAAAGTACAAACATGACCAAATGTTGGACTTTGCCCTTCCAATGTAGATTC ATAGTTTGAAGGACAGAATGAAATATAAATTGATAAATGTAAACCAGTTGAAAAACTGCC TCAGTAAAGGTGTGTATGGGGTACAATAGGAGCAGAGACTTCTGATTTGCCATCTAAAGG GTGAACTAGAGTCCTTGACGCACACAACAGGGAAGAGACATGCCTGGTGGAACCCAAGGT ATGTGCAAAGCTGGAAGAGAAGGAAACAAATAGGAAGGGATTGCTTTTCGACAAGAAACC AGAGCAGATCTTTGAATAGCAGAATTTCTAGCATAGTCAGCAAAAGAAATAAACATTACC TTTTTCACTATGAGGATTTAAAGATGAGTGAACATGACAGGAAACTTCAATCTAAAACAA TCTGTAGCCTAAGAGAAACTTTGTATCACCAATCCAGAATCAACTTGTGGTACTTTGAAG AGTGTTTTTTTTGTTTGTTTGTTGATTTGTTTTGTTCCCCCCCCCACCCCGCAAAGGGAG CGGATCACAAAAGAATTGAAAAACACAGTGATAGACCTGGGGAAAATAAAGACAGTATTT CTATGTCCTTGAAACAATTGGGCAATGAGAAGGAATCTAGAGCTGGAAATGTGATAACCC AGTGTGAACACACACAAAAGTCTCGGCATCCTGTTCTACATGTCAAAGAGGAGAGTCGGT GATCTCTTTCTGGGAACTGTAGATGAGAAGTCTTGAGTTTTTCTTCTGCACATTTTGAAA GGCATATTTCATAAGAACTTAACTTTCAAGGGCAAATAACACGCATGGCTTCCCCCTGTG TTGTCCTCACTTTTACAAAGGAGTTCTTCCTACTCTCTTACCACGTGCTCCCCCCAGAGA TTTGGTACCAGACACATGTGGCTGTTATACATGATGGAAATCCCTTCCATGGACGTTATT CCTACCCATGAAGGAAAGGAGTCTGAAAGCTGAAATAATCTGCCAAAGATCAAACAGCTG TTAAGTAATGGAGCCTAGACCCAATCTCTGATCTTCCAATGGCAAAACCTATGCTCTGTC AACTTTATGGTACTAATTACAATGATTTATAATTTCATTTAAAACATTTATTTAAGTGGC TTGGTATTTTCCAAATATAATTCCAGTAGAACCACAGGAGAGACCTGGGCTAAATGAATA CCTCCAGGAAATAGCACAGAACACTCTTAACTTCATTATTACTTCTTAAATTATTACTTA AGTTGCTACAATTACTGCTGAACTTACTAATGAAATTGGTAAAATGCCAAAACAGCAGGA AAGGATCGGCATATAAATCACTCAATTCCTTGTCAAATAAGCTTAAGTACTGTTAATCAG AAGTATGCCAGTTTTGATTTTAAAATCCTGTTTATTTTTCTCTGAGGATTTCACACCATG TAGAAATTAAAAAAAAAATGAAACGATGACGATGACAACAAAAGCAGGTACTCTATAATT TTTTTAAAATTTTCAACAAGTGAGAATTTTAATGAATTAAGGGAAAACACTAGTAATCTA CTAAGCCTGAGAAGCAAAGATAAAAATTCCTTAAGAACAGCAACAAAGATAGCTTCCTCT TTAAGTTATGAAGGTGATTTCTTAAAATGTCAGCATTTCCTGAAATAATATTAAATATGC TCTGATTTTGCACTAATTTTCAATAATAGGAATTCTAGGTCAGAAAAAACTGCAAAATTA ATATTTCTTTGTGACTTTCACTGACTGGCAAAGTAAAACTATGTTATAAATGTACTTGTA AAAGCAATAAACATGTATTTATCCTTTGCAATTAAATTGTTGAAGTAAATGATAAAACTG TTGAATATCTCAGTGGAGAGATAATTGAATATTTTATATGAGCAAGCACTCTCCCCTAGA ATTTGTCATGTATTCTGATTTTATAGCTGCTAAAAATAGAATTGTTTTTCAAATTTAATC ATTCAAAAAATTTTTGATTATTAGTTTTTGGCCATAAATAAATAGACAGCTTTTTCATGT CTCATTGTCATATTTAAAAAGAGGTGCTTTTGAACAAAATCAGTTGTCCTATAGGCAGCA CAAGGTACTCAGTAGGGGTCTAAATATTAAAAAGAATGACATTTTTTTTTTTTTGTGAGT CAGATAAATTTTACATAAGGTTGAATAGTACTAGAGCTTCAGGATTTGATACCATGTTTT CTACAATTCTGCTCACTCTCTGTGGCCCCTTAATACTTCTTGTCCCTGCTTAAAACAACA ACAACAACAGCAACAACAAATCTCTTCAGGCCATTTCTTTAATCCAAAGATACACTGTTA TGTAGATGTCAACTGGGTCATATTTCACTATAAAAGAATAGAGCGACTTCATTAGCTTAA ACATATATATCGACAATATGTTCGACTCATTCTTCTCATGGCTACCAATTAAAATCTAGC AGAAAACCATTAAATTGTTAAAATAAGATGCAAACTAAGCAGAATGAAGCAACTATAGGT TGTTTATCTATCACCAGGAAGACATGCTCAATCTTTAAGAGAAATCATGATCTCATGATC TACTTGCTCATATAACATTTCATTGAGTCAATCTAAAATTCCTCAAGTGCTCTCTAAAAA TCTAGTTTCTGATAGGTGTTACATTTTTTGAAATTTTGGAGAAAACAACCACAGTCTCCT TCCCTATAGGTGTTTCTAGGAAGTTTGGTAAAATTTTGACAATTAGCAGTGGATTTCCCC AGCGTTCTTGAGAACTGGTCAAATTCTACTGAAGTTCAGACTTACAAATATTTTCCCCTC TTTTTTTTCCCAACTTATTTTTCTGCCTGGGGCGTTCGTTTTATAACCAAAGTTATACTG GCACCCCTGTTTTTAAAACCTTTTTGAGTCAACTGTGGTAACACCTAATTCCAGACTCAA CCTTAGTGGCAGAAATTGTAAAGCAACTGAGAGGATTCATGCTCTGGTAGGCTTTTAAAT ATGAAGAGTTTACTTTCTCTTTTATCCTGTACAGTATAATCAGCAATAAAAGTTATCTCT TGGGGGATGAAGAATAAACCAAGGTATAAACTGCAAAAGACATGTTTACCTAGGTATATT GCATTACCCCCCAATGAAAAACTGCACATTCCTAAATATATAAATGAATAATAAGGACCA CTTATCATGCATGCAATTTTTTTTTACTACTACTGTACTTTTGATTAAATTTCTGAAATA GTCCTAAAATAGAACTCATGAGTTCAGGTTGTGGCTGTAAACATAAAACTCTCTGTCAGT CCAAGTGGAAATGGTGTTGCCACCTTGAGTATTTGGAAAAATAGAAGAAAGAGTTTGCTA CAAATATCCCAGTAGCAAAATATTTCCTGCCAATTGCACATGGTGCAATTTGTCATCTCA CATCCATGCTCCTGGGCGTACCTGTCTACAGACGATCCTCTTGTTCCGACCAGTACTCAA CAGAAGATGGCGAGGACCGTGTCTGTCGTGTCTATGCTCGTGGCTGCAACCCCAGCATCT AGCATAGCGTCAGGCACAGGACCAATGCTCAATGTGCCTGGCCCTGTGTGGAATAGAAGC AAATTAGTGCACAGCCCTAATGTGCAATGTGCGGTGAAACCTAACAGAGGAATGAGTTAG GTCAGGAGAGCAGCAGGCTGGGGAGTGTGTAACAAGCCTGGCCCACTTTTGGTATTTTGC CTAAAAATTTCCCATGCGGTGTTTCAAATAATATAAACAAATGAGGTGATTTAACTTCTA AAACTTTATTTTGCTTTGAAATGCAAACTTTTAACAAATAGCTACATAAATTCCTTTTTC GATAACCATGAAAGAGGACATATTCACTTAAAATAGAAATCATGCCAGGTAATAAAATGT TCAGTATGGTAATTCATTAAAGCAAGTACTAAGTACATTATTCACATGGCTATAAAAGCA CCATCACTTTTCATGTGTTTATTAATTTTAGGCTCAAGGGTATTAAAATATTCTCGCTCT GTCTCTCCTTTTTCCCCCTTTTTTTTGGTTCCATTTCATCCTTTTTTCTGTCTACATGGA AATATGCTTACCTTGCTTTAGGTAAATACATTAGTGAACACAAAACCAAGTGACATATTT CAGCAAATTTGGGTACATTTTATATACAATGAAACAATCTTGGAAATCCAAGAACCCCTA CCAGAAAGAAAAAGCAGAACGCCTCCTTCAGTTAGATAAAGTGCCTCTCTCTACTTTTTG TTGTTGTTTCTTTATTTGTAGATTTCTTGCTTAACTCTGAAACTTCCTGAGATATTTTAT TAAACCCTATACCCTATTTTGGAAGCTCATTTATTTTCTAAGAAATCTTGGCAGAATATA TGTTCTCATTTTAATTGCATAATTATCTGGAGCGGTGGAAAACAGATGTCTTATATTGAT GTAAGCACTAACAAAACCATAGGTGTTGTTTTCATATGACTCACCTTGCCACGGATTTGC ACATCTCACTTACTGAGCCAAAACACAAGAATAGAAGGTTATACCCAGAATCAACATGAC CTGCCTAATGATGCAAGTTTAATGGGACCATTATTAGTTCTGTCCCTGCTAATAATAATA GAATTATAAGGAGTTTTGTTTCCCCTTTTTGTTGTTTACAAGTTTGTCATATATTTAGAA GTCATTGTTTCTTGCTTTTCCTAACCCTCCTCCCCACCCTGGGTGTAGTGAAATTATTAG GAGGTGGAGCACAGGGTATTGTTACAGCCCATGTCATAGAAAAAAGATATTTATTTGCTT ACTCTGTGGTGAGTGAAGCATTTGATTCCCACTTACTGAGAAATGCGGTGGCCATGCGAT GAGAAGCAGCGGCAGGGCATTGAGAACGAACCTTATCTCTGGGTGCACTTTTTAACTTAG AGGCGGTTCTTCACTCTTTCATCATCACGGCTGTAATGGTTAAAAACTCTCAGGCAGCTT CCTTCATGATGGGATGGCAACACGTTTTCTCTAAGCAAATATGGAGGAGGATTTGTACAG AGCAACTGTGCAGGAGCTGAACTGGAACTCCCAACAACCAAACTGCTGTCAAACGAAAGA ATCTCTCGTCCAGATAGCCATTATCTGATAACTGTCTTGTCTGCATTTTCACTCTCTTTC AGAGTTGGTTTGCTCTCTTCAGGAGTGGGAATTAACTTTTACTCATGGTGACAAGGTAAA CAAGTTTTCCGTGGGTACTCTAAAGCGTTGCATTTCTGTTTTGTTTATGTGCCTTGTTTG GCTACAGTAGTTACTGTGCCTCTGTCTCCTAGGCAACACTGACACATGATTTGATAGGAA GTAAGGCCTGAGGAGTACCCTCTCCCCACTCACTAGGCAATAGCAGCAATTCTCTGCCCT TAGAGAACCGCCTTAGCTCTTCTCTGCTTTGTGAGCAGGTCTGGTACCCTCAAGTAAATA TGTGTGGGGGATGCGTTTCTGGGTGTGATAAATTGCTGCTGTCTGTCACCTGAGATCATC CTACACAAATTGTAACAATGGCAGTGTTGGTCTGTGGGTGCACCCAAGACCACCTTCCTC ACGTCACATCCATTTTACCACCCAGCTGTCTTCAGAATGCTTCAATTTCAGCAAACCTCC TTGGCTTTTCCTGTCCTTTGTTCCATTTCTGTTTGATTCCTTCTGGGGAATTTCGAGGTG GCTAGCTAGCAAAGCTGGCTTTAAAAAAGTAGCTTAGCGTGTGAATAGATAAGAGTAGTG CTTATTGTATGACCCACGGCAGAGAGTAGTAAGTAGTTGCCTTTGGAAGGAGACCTTCAG TCTAGCCTAAGCGATGAGTGATGCAGGATTCCCTGTCTCCTTAGGAGCTGACTGGGAGAG TCTCAGACAGAGCAGATGCAGAAAGATGGTGGCCCAGGTTGGATCAGTGGTTCTGTTTGT GAGATGAGAGACAGGCTTCCTGGAGGCAATTTCCAAAAGGCTCAGTGTAGAAGCTGTGCA AGTACAGTCAGCGTGTGTGCCTGGGGTTCCCAAGGTGACCATTTTAGCAGTTGCCAAAAT GAAACCGGAGCAATTGTTATCAGGTTGAAAATTGTTGTCAGACCTGAAAAATGTGATTTT CCTCGGGGAAAGGGGAAGTAAAACAAGGAACAGAGAGAGATCCATTTATTTGCTAAGAGG CACCCAGAAAAGTTTAGATATAGTATCAACTATCTGGCCTACTCTTTTAAGTCCTGCCCA TCTGTTTATACATGTAACATATTTGTCACTAATGAAACCTTAAAAATACTTATTAATCAT TGGGAAGACAGTAATTTCTGGCTTAAAAGCCTGCTTTAATGGCCTCTCTCCGTATATATA TATGTATATTTTTTGAGATGAAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCA ATCTCTGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCTTGCCTCAGCCTCC CGAGTAGTTGGGATTACAGGCACCCGCCACCACGCCTGGCTAATTTTTTGTATTTTTGGT AGAGATGGGGTTTCACCATGTTGGCCAGGCTTGTCTCAAATTCCTGACCTCAAGTGATGC ACCCGCCTTGGCCTCTTAAAGTTCTGGGATTACAGGTGTGAGCCACCACACTCAGCCAAT GGTCTGTATATTTCTTACATTCATTTACTCAAATATTCATTGAATGCACCTATGCACTAT GCTAGGCGCGGTGAAGGGTATAAAGAAAATTAGATCTGGCTGCTCCTTCCATACCACCTT CCTGGGTATATGATCTTTAATTAACTACGCCAATAAAAACAAACAAACAAACAAAGCAAA CACATGCTCATACAGAAACACTGTCTCTATGTTTCTGTATAAGCACAAACGAAAAAATGA GAGGCAGGGACTTTTTTTTTTTCTGGCGGGGGGTTGCGGGGGGGTTGTTTGTTTGTTTTG AGATGGAATTTCAGTCTTGTTGCCTAGGCTGGAGTGCAATGGCGCGATCTCAGCTCACCA CAACCTCCACCTCCCGGGTTCAACCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAT TACAGGCCCCCGCCACCACACCCAGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTT CACCACGCTGGTCAGTCTGGTCTTGAACTCCTGACAGGTGATCCACCCACCTCGGCCTCC CAAAGTGCTGGGATTACAGACGTGAGCCACTGAGCGAGGCCTGTTTGGTTTTTTATGGCA ATAATTTAATTCTTTATAATAAAGTGTAAACGTCCAAAGACAGTATGATAGAACATGCTG GAAGAATTCACAAAAGTCGTTTTTTTAAAAAGTGAAATTAAATGTGTCTGCATCCTTTAA GCAAAACAATGTGAGTTTAGCCAAATAGAAATATGAATAGTAATAAAACGAAAATCATGG TTCAGTGGCTCTACCATGAACTTTGGTTAAAGGAGCTTATTAAAGGTATCAACTTCTAGA ACTTGATTCCATGGAAATAATGGAAAAATGTAGATCAAGATTTATACAAAAGAGAGCAAA ATTCATTGTACCTTTACAATAGTAAAATAGTAAAAGTACTATAGGAATGGTGAAGAGAAA TATGTAACTGCTCAAGGTTGAAATATGTGATGTGGATGTCAAAAGGAATGTTTATCAATA ACTTTTTTTTTTCTTTTGAGACAGGGTGGTGCCCTGTCACCCAGGCTGGAGTGCAGTGGC AGGATCTCGGCTCACTGCAGTCTCTGCCTCCTGGGTTCAAGTGATTCTCGTGCCTTAGCC CCCGGAGTAGCTGGGATTGCAGGCATGTGCCACCATGCCAGATAATTTTTGTATTTTTAG TAGGGAGAGGGTTTCACCATGTTGGCCAGGGTGGTCTCAAACTCCTGGCTTGTGATCCTC CCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCAATCAAGAACTTTTAATA ACATAGGGTATTATGAAAAAATGTTAAGTAAAAACAACAGGAGGGTATACACACATGTAA TTTTTTTTTACAGTCTTATTTTTGGTCAGAAGATCAGACTAACAGGAATAGTTATCTCTA AGTGGTAGGTGTATTAGTCAGCTATTGCTACAGAACAAGCAACCACAGAACCCTCAGTGG TAAACTGTGATAGGCATGTATTTGTAGCCCATGTGTCTGAGTTTTGACTGGGGTCTGCTT AATCTTGGGCTGGGATCCAGATCACAAAGTGAGTTCAGATTTGTTCCAAGTATCTGCCAT TCATTTGGAACCAGTGGCTACCCAGGGCATAATCTTTTTATGGTGACAGCAAAAGTGCAA GAGAGCAGGACCAACTGCACAAGCACGCATCAAGCATCTGCTCATGTCACATTCCCTGAC ATCTCAAGAGGCTGAGCAAATTGCATGGCCAAGCCCGGAGTCAAATGGACGAAGCCCAAA GTACATTCCACCATGATAAGGCCATGATAAGGATGTGGACATGGACAACTCCTAGTGGGG AGTGAAGAAATGGGACCAACAGTTCATTCTACCACGGCAGGGTTAGTGTTTCTCTTACTT TTATTCTGTGTTTCTATATTTACAAACGTTTTATTCTGTACAAATGCAGGCAGAAAAAGT TATTTTAAAAAATATTAGAGACATACAGATCAATTTAATAGAATTGAGAGTCAAAAATAA ACTCTCGCATTTAGGGTCAATTGATTTTTGACAAGAGTGTCAAGACAATTCAGCGGGGAA AAGATCAGCCTTTCAATAAGTGGTGCATATCCACATGCAAAAGAATGCCTCGCAGCATAG ACAAAAATGAATTCCAATGGGATCAAAGACCTAAAAGTAAGAGGCAAAACTATAAAATTC TTAGAAGAAAACATAGGCATAAATCTTCATGACCTTCATTTTGTTTCTTTCTTTTTTTTT TTTTTTTTTTTTGAGACAGAATCTTACTCTGTCGCCTAGGCTGGAGTGCAGTGGTATGAT CTCAGCTCACTGCCAACTCCCCTGCCTCCTGGATTCATGCGATTCTCCTGCCTCAGCCTC CCGAGAAGTTGGGATTACAGGCGTGTGCCACCACACCCGGCTAAGTTTTATATTTTTACT AGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGATCTCAGGTGATCC ACCCACCTTGGCCTCCCAAAGAGCTGGGATTACAGGCATGAGCCGCCGCACCTACCCAAT GGTTTCTTCAATAAGATACAAAAGCAGACACAACAAAAGAAAAAAATAGATAAACTGGAT TTCACCAAAATTAAAAGCTTTTGTGCTTCAAAGGATACCATGAAGAAAGTGAAAAAAGAC CGGATGCAGTGGCTCACGTCTCTAATCCCAGCACTTTGGGAAGCCAAGGTAGGCAGATCA CCTGAGGTCAGGAGTTTAAGACCAGCCTGACCAGCATGGTGAAACCCTGTCTCTACTAAA AAACACAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAATCCCAGCTACTCAAAGGCT GAGACAGGAGAATGGCTTGAACTCGGGAGGCGAAGGTTGCAGTGAGCTGAGATCGTGCCA CTGCACTCCAGCCTGGTCAACAGAGCAAGACTCTGTCTGAAATAAAATAAAATAAAATAC AAGGAAGTGAAAAGACAAGCCACAGCATGGGAAAAATATTTGCAAAGACATATCTGACAA GGAACTTTTATTTAGAATATGTCAAAAACTCTTAAAACCAAACAATAAAAAGAAAAATAA CCCACTTTAGCCTGTAATACCAGCACTTTGGGAGGTTGAGGTGGGAGGATAGCTTGAGCC CAGGAGTTTGAGGCTCTGGTGAGTCGTGTTCGTGCCACTGTACTCCAGTCTGGGTGACAG AGCAAGACCTTTCTCAAAAAACGAAAGAAAGATAGAAAGAAAAAAGTAAAATAACCCAGT TTAAGCATGGGATAAAGAATTTGAACAGACATATCTCCAGAGAAGATGTACCAACAGCAA AGGTGCCTAGGAACATCTGCTCCATATCATTAGCTATTGGAAATGCAAATGAAAACCACA CTGAGATACCTCTTCACACCCACTCCAATGGCTGAAATGAAAAGGACAATAACAACTGTT GATGAAGATGTGGAAACACTGGAACCCTCACATACTGTTGCTGGGGAGGTAAAGTGAGGT GGCCAATTTGGAAAACAGCCTGGCAGTTCGTCAAAAGGTTAAATGTGGAGTTCCCATACG ACTGAGTAATTGCATTCCTAGGCAAATACCCACCCAAGAGAGTTAAAATCATGTGTCTAC ATAAAAATTTATATGTGAATATTCACAGAAGAATTAGTTATAATGGCCAAAGAGTGAAAA CAGCCCAAATGTCCAGCAACTGATGAATGGATAAAGAATATGTGGTATATCCATGCCGTG AAATATTATTCAGCCATCAAAAGAAGCACTGATACTACAACATGGATGAACCTTGAACAC ATGAAGCTAAGTAAAAGAAGTCAGTCACAAAAGATCACACACTGCATGATTCCACTTATA TGAAATGTCCAGGATAAGCAAATCTATAGAGATAGAAAATAGATTCATGGTTGCCTAGGG CTGCCGGGGGATGGAGGGAGTTTGGGAAAAATAAGAAGTTACTGCTAATGGGTATGAGAT TTTCTTCTGGGATAACACAAATATTTTAAATTGATTGTATTGATGGTTTCCAACTCTGTG AATATATTACAACCATTGACTTGTACGCTTTGAATAGGTGAATTTTATGATATGTAAGTT ATATCTCAATAAAACTGTCATTAAAAAATACCCTAGCAGGATTAGATACCCTCAAAGGAT TGAAACAGAATTCTGGGTAATCGTTAGAAAAATTCTAGTGTAAAATCAATCTGTTGAGTT ATCCCATGTAGCTAAAATTAAAAGCATATCTTTATTCAGTAAAGAATTTCAGTAGCTTAA GCTTTTTTCAGTTCTTTAGTCCTTTTTTCAGTTCTTTAGTCAGAGACCAGTTCTTTGCTC TGAAAACCAGATACAGGAAATCAACCAGAATGTGTAAAAACAATAGCAAAAACTACACAA TTAAACTTCTTCTTCTTATTATTATTATTATTATTTTGAGATGGAGTCTCTTTCTGTCAC CCAGGCTGGAGTGCAGTGGTACGATCTAGGCTCACTGCAACTTCTGCCTTCTGAGTTCAA GCTATTCTCCTGCCTCAGCCTCCTGAGTAGCCAGGACTACAGGTGTGCGCCACTACGCCC GGCTATTTTTTTTTTTTGTATTTTTTAGTACAGATGGGGTTTCGCCATGTTGGCAAGGCT GCTCTCGAACTCCTGACCTCAGGTGGTCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATT ACAGGCATGAGCCACCACACCTGGGCTAAACTTATGTTGTTAATGTAGATTAATGTCCCA TTTCAGTCAAAAGAGAAGCTACCATGTTCCTGGGACTGTCAGTTGCCTTATACACACGAT CACATCACAGCTCTATAAACCTCTTTTACAGATGAGTATACTGAGGCTTAGAGAATTTAC ATAGCACAGACTCTTTGTGATGCTCTCCAAATTCACATTGCCTAGAATGTCAAAACCTTA ATTCCATGATTGTCATAATTATTATTTTCACAAAACAGTACAATTGTTTAACTTGGACTG TCTGATTTGATGGTGGTGAGTGTGGAGTTCCTCTTGAGAAACTCCTGATTATTTCAGAAT AAGTCTGAATGTGATGTTATTTGGGAAGATCACTCTCTCTCTTGTCTTTCCCTCAAGTGT GCATTAAACTGCTGCTTGTATTTGTCTATTTAACATTATATATATATATATGTTATATAT ATATATTTATATATATATGTTATATATATATATTTATATATATATGTTATATATATAAAA TATGTAATTTTTTTGAGGGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGCGGTGCAATCA TGACTCACTGCAGTTCGAACTCCTGCACTCAAGCGATTCTCCTGCTTCAGCCCTCCAAGT AGTTACGACTACAAGCGCACACCACCATGCCAGGATAATTTTTGTATTTTTTGTAGAGAG AAGATTTCGTCATATTGCCCAGGCTGGTCTCGAACTCCTAAGCTCAAGTGATAAACCCGC GTTGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCATGCCTGGCCTCATTTAAA TTTTATATCATACCAAATATTATGTTTATATCTCTGTCTCCACCACAGAGATGGCCAGGT GCAAGTCTCATACCTCCGATCTGAATGTAGATTAGACAATAGGTCTTTATTTTATCGAGC TTGGTTTTGCCAGAATTCATCCTAGTATCCAGCACACAGAGGAGGTCCTCGTGCTTTAAG GAAAGAGGGTTTCTGTTTTTGTAAAAGGGAATTCCATTTGAACCTATATTTTGAAGGTAA AAAATGCAATGGAGAACATCACAAGGAAACTGAATTAGGCTCCTCTTGATTCTGATCTGA GGCTGCTGATAATTCAGAATTTTGAAGGTGATTATTCTCAGTCTTTACCCTTGGGCCTTT GTTCTTTTAACTATTATTGAAGTCTCATCTTTTAAAATTAATGACCCGGTATGACATTTC AGAGCAGCTAAAATTGATTTGTCTATTTACTTACCTCTTTTAAAAGTAAAATAAAATTGC ATTTGTGTGTAAAATCCCCCAGCACCAATGAAAATTGCGATTCTACATTTGCTGAGAAAT ATCTTTATTTGTCCTCTGGGAGATCTTAAACTTTAGTTGCCTTCTATTAAACTTTTATGA GAACAAAACTAGCAAATGACTTTTTCCCCAAACAGGTACTTTTGGTTGTTTCAAAGAAAG AATACATTCTTGAAACAGAACTTGTTCTTTTAAACAAATTACTCAGTGTCACTTACAATG AAAAGTGAGGGTGGGGAGGGGTGTGAATAAATTGCACAATATTAAAATTAGGTCATATTT ATGTTTTTTCTGACTTGTCTAAATATTGCCTCAAATATCTTCCCCAGGAGGCCTAAAGTG CTATAATTTAAGTTTTTTGCAGAGACAGAGTTACACTATGTTACCCAGGTTAGTCTCAAA CTCCTGGGCTCAAATGATCCTCCTGCTTCAGCCTCCTTAAATGCTAGGATTACAGGTGTG AGCCACTGTGCCCAGCCTAACCCATATTTTTATGGAAAGCATTATTTTCCCTTCACTGTC CTTTTTTATTTATTTTTGAGTTGGAATCTTGCTAGGTTGCTGAGGCTGGAGTGCAGTAGT ACAATCATGGCTCACTGCGGCCTCAATCTCCTGGGCTCAAGTGACCCTCCCACCTTAGCC TCCCAAGGAGCTGGGACTACAGGCTTGTGCCACCGCACTTCGCTGCTTTTTTTAAAAAAA TCTATTTTTAGTAGAGACAAGGTCTGGCCATGTTCCTGGTGCTGGTCTCTAATTCCTTAG CTCAAGTGATCCTCCAACTTTGGCCTCCCAAAGTGCTGGGATTGCAGGTGTGAGCCACTG CACCCAGCCTAATTCCTATTTTTATGGAAAGCATTATTCTTCCTTCTCTGTCCTATTTTA AAATATAAGTGCACTGGGAACAGTGATATGTTAGGGAAGGCTGATGTGGAGGGGACAGTC CTAGAGTAATTGCTGGTGGGCAGTGGCGAACTCCATCAGTAAGGTCTCACCCTGCTATTT GATGGGTCTACCTCTACTCGGCTGTGGGTTTTCATTTGAAATCGAACTACCTGTGGCTCA TGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATCACCTGAGGTCAGTAGTT GCAGACCAGCCTGGCCAACATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGTG GGGCGTGTTGGTGGGCACCTGTAATTCCAGCTACTCTGGAGGCTGATGCAGGAGAAACGC TTAAACTCGGGAGGCAGAGTTTGCAGTGAGCTGAGATTGCACCACTGCACTCCAGCCTGG GCGACAGAGTGAAACTCCATCTTAAAAAAAAAAAAAAGTAAAATAAAAAATTAAATGAAT AAATGAAATTGAACTACCTGCCTAAAACCCAGAAAGGTGGGTGGGGCTGGGGGGAATAGA AAGAGTATTCAGCATTGAGGCTGATGCAGTTAATGCTAAGTCGAGCCATCAATTCTTTGT GACATCATTTTCCTTGATAGTCCTGTTATCTTTTCATCCACTAAGTTACTAAAGCACAGG CTCGGAGGTTGTGGTAGGCAGCCCTGTGGACCCATTTTAGACTTCTGACCTCCAGGACTG TGAGATGATACACCAATGTGGTTTTAAGCCTTGAAGTCTGTGGTAATTTGTCACAGCAGC CATAGGAAATGAATGCAGGGGTCTTTCCTCATGTCTCATTCCACTCCACCCTCACCGCCT TCCAGTTTGACTCTAGCATTCACTCAGTTCTCTTCCCCACTGTGGCAACGTGCTGGCCCA CCCTCCTGGGCATAACTGCCCCAGCCTCTTGCTTGGGCTCTCCAACCCATTTTCATGCTG CAGTCTGCCTGATGGCAGGAAACCACAGATAGGTTTATGAAAACCCCTGCTTTGAAAAAC CTTTAATATCTTGCTATTGCCATTAAAATTAAATCCAGATGTCATCCCGAGAAGCACCCA GCACTGCATGCTCTAGTCCCTGCCGTCTTCTCCAGCCTTATCAGTGTTCAATGGTGGTTT TGAGGCAGAATATCTGGCTCCAAATTCTGCTTGTGCCACTTACTCTCTGTAGGACCTTAG ACAAATAAACCTCTCTATGCCTCAGTTTCCTCTTCTATACAGTACCTAATTGGATGTTTG TGAAGATTAAACAAATTAATCAAAATAAAATGCCTGGCACTATTCTAAACACAATACCAT TGGTAGGTAGCCTTATTCTTACTGTATTACCCATGCCACTGGCAAATTGTGAGCACTGAA ACCTCTGGTGAATGAATGAATGCATAAATGAATGGAAGTAATGTTACATTCACAACTTCT CTGTGTGTACCATTGCTTCTCTCTCTAGTGTGCAGAATGAATCAGTGTCACAGACACATA GTCAAAATTTAGATAAGCCAAGAGACAATTGAACACTGGGGAGCCACATTTTGGCTACTA GATGTACAAAGAACGGATCTAAGATCTGGTTTACTATGAAGAAAGATGGAAGCTCTTTGA GGCAATTGCTAAACTCTTGAGGGCATCTCTAGTAAGCACTGAAGGACACTCGAACCAGTG TTCAGACCTAACATTGGTGTATCTAAGAAATATTGATATATACTTCTAAGCTGTTCTTAT CTTACTTTTCTGATTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTATTGCCCAGGC TGGAGTGCAGTGGTGGGATCTTGGCTCACTGCAACCTCCACCTCCCACGTTTGAGCGACT CTCTTGCTTCAGCCTCCCGAGTAGCTGGGATTTCAGTCATGTGCCATCAGGCCCAGATAG TTTTTGTATTATTATTCTTTTTTTTAGTAGAAACAGAGTTTCACCAAGTTGGCCAGGCTG GTCTCAAACTCCTGGCCTCAAGTGATCTGCATGTCTCAGCCTCCCAAATTGAGCCACCAC TCCTGGCCTCCTGAATTTATTTAATAATGTGTAGCCTTCTAACTGAAGAGTAATATTCAT GACTGTGGTGTTTCCACAGAAAGGTATAAACTTGCCAGATGCTAACAGCACTCCCTGTCT ATGGTATTTACTTTTGGGTATGTTCTACAGAGAGAGAATATTTCCAGTAGGATTTCTGTG CAGTAAATGTCAGTTCCTTTGCAGATAAAGTTTTATTTCCTTTAGGATGGGTCTATATTA AGAGATAATAGAAAACGTCTTGTGTGGGAGAGAGGAGTTTGAGACCGCTTTGGTTGTCTT CACCATGTCCTAAGGGGTTGAACTGGGCATTCTGTCCAGAGTTCTTTCACCCTTTAGTTT AATGACCTCAAAGTTCTGTCCTGCTTTCATAGGTACATACTTCAATAATTGAATTTTCAT GTTCTTAATTTTTTTTGCTAATATATAAAAATGTAATTACTTTTGGGGGGAGGCTTATTG AGGTATAATTTATAAGCAGGAAAGTTTACCTTTTAAATGTACTTGGTATGGTTTGGGTGT GTGTCCCCATTCAAATCTCTCATCAAATTGTAATCTCCAATATTGGAGGTGGGGCCTGGT GGGAAGTGACTGGATCATGGGGGTGGATTTCCCCATCAGTGCTGTTCTTCTCATAGTGAG TTGCAGTGAGATCTGGCAATTTAAAAGTGTGCAGTACCTCCCCACCACTCCTTTTTCCCA CTCTGGCCATGTAAGAGGAGCCTACTTCCCCTTCACCTTCCACCATGTCTGCAAGTTTCC TGAGGCGTCCCCAACCATGAGCCGACCGAACGAACCATGAGCCAATTAAACCTCTTTTTT TTTTTTTTTTGAGACGGAGTGTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCT CGGCGATCTCGGCTCACTGCAAACTCCGCCTCCCGGGTTCACCCCATTCTCCTGCCTCAG CCTCCCGAGCAGCTGCGATTACAGGCGCCCGCCACCACACCCGACTATTTTTTTGTATTT TTAGTAGAGACGGGGTTTCACCGTGTTAGCCAAGATGGTCTCGATCTCCTGACCTCGTGA TCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCTTGAGCCACCGCACCTGGCC TTAAACCTCTTTTCTTTATAAATTACCCAGTCGCAAGTATTTCTTTATAGCAGTGTGAGA ATGGACTAATACAATACTGTTCTATGCATTATGGCAAATACAGAGTTATTTAATCACCAC TATAATCAAAACATAGAACAAATCTATCACCTTTCTCTCCCCTCAAAATTCTCTCATGCG CTTTCGTAGTAAATACCTCATCCCATCTTGAGCCCCCTGGCAAGAACTGATCATTTTTTC TCTCTACAGTTTTGCCTTTTTTTTTTTTTGAGATGGATCCTTGCCCTGTTGCCCAGGCTG GAGTGCAATGGTGTCATCTCAGCTCATTGCAACCCCTGCCTCCCTGGTTCAATTGATTCT CCTGCCTCAGCCTCCCGAGTAGCTGGGATTATAGGTGCCCACCACCACGCCCAGCTAATT TTTGTATTTTTCATAGAGATGGGTTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTG GCCTCGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTG TGCCCGACCTATAGTTTTGCCTTTTCTGGATGTCATATGAATGGAGTCTATTATATGCAG CCTCTTGAAAGGGGCTTTCTTCACTTGAGAGTCAGATGTGTTGCTGTGTGTATCAGCAGT TTGTTCTTTCATCTTGCTCAGTAGTATTCCATTGTATGGATATGCTCCAGGTTGCTTATC CATTCATCTGCTGGAAGAAATCTGGGTTATTTCCAGTTTGGAATAATTATAAATAAAGTG ACTACACCACTCACATACACGTTTTAGTGTGAACATAAGTTTTTATTTCTCTCAGGTAAA TATCTAGGAGTGGGACTGCTGGGCCATAAGCTATATGTATAGCTAGTCTTATCAGACACC AGTAAACTGTTTACCAAAGTGGCTGGGCCAGTTTGTATTCCCACCCACGGTGTATGAGAG TTGCAGTTGCTCTTCATTCTCATCAGCATTTGATATTTCCAGGTGTTTCAATTTTAGACA TTCTAATGGGTATGTAAAGGTATCTCATTGTTGGCCAGGCGTGGTGGCTCGTGCCTGTAA TCCCAGCACTTTGGGAGGCTGAGGCGGCAGATCACAAGGTCAGAAGTTCAAGACCAGCCT GGCCAATATAGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGC ACGTGCCTGTAATCCCAGCTACTCAGAAGGCTCAGGCAGCAGACTGCTTGAACCTGGCAG GCATAGGTTGCAGTAGGCCGAGACTATGCCATTGCACTCCAGCCTAGGGGAAAGAGTGAG ACTCCGTCTTAAAAAAACAAAAAGGTATCTCATTGTTGTATAATTTGTATTTCCCTAGTG ATTTTATATATATATATATATAATATTTTAGACAATGTCTCACTCTGTTGTCCAGGCTGG AATGCAGTGGTGCAATCACAGCTCAATGCAGCCTGGACCTCCTGGGCTCAAAGTGTTTCT CCCACTTCAGCCTCCTGAGTAACTGGGAATACAGGCACGCAACAGCAACCCCGGCTATTA AAAAATAAATTATAGAGAAAGGGTCTCATTATATTGCCCAGGCTGGGCTCAAACTCCTGG GCTCAAATGATCCTCCCACCTTAACCTCCCAAAGTGCTGGGATTACAGGCAAGGGCCACC ATATCTGGCCTCTTAGCGATTGATGAGTATCTTTATATATGTTTGGTTGCTAACCATATA GCTTCTCTTATTACGCTTATTTCTTCATATGTGATATATATTTTTATGTACTATATTTTT GCTGATAATATATAAAAATAGAATTGATTTATGTATATTAACCTGGTATCCTGAGACCTT CCTAAATTTACTTGTTAGTTCTAGTAGTAGTTTTGTCAGTTCCTATGATTTCTGTATAAA CCACCATCATGTCATCTGAAAATAGGGACAATTTTACTTCCTTTTGAATTGTTACACTTT CCATATCTTTTTCTTGCTTTGTTAATGGTTATAAACTACAGACAAATGTTAAGAAGTGGT AAGATGAGGCATCCTTGCCTTCTTCCTGATATAAGGGGGAGAGTGTTCAATATATTACCA CTAAGTCTGATATTGGCTATGGATTTTTCATGAATGACCTTTACTATATTGAGGAAGTCC CTTCTAATTTTTTTGGCAGTTTTTATGAGTAGGGATTGAATTTTAAGTGGTCTTTCTGCA TCTATTGTGATGACAACAGTTTTTCTTTTTCAGTTAATATGGTGAATTACGTTGATTGGT TTTAGATCATTAAATACAACTTGCATTCCTTGCACTGGGGACAAACCCAAATTGATCATG ATGTATTATCTTTCTATATACTGTTGGATTCAATTTCCTAACATTTTATTAAAGTTGTTT TTGTTTCTATGGTCATGTGGTATATTAAGCTGTATATTAATTTTTTTGTAGTGTTGATTT TATGTTATGCGGGTTATGCTGGCCTCAAAATGAGAGGAAAACTGTTTCCTCCTCTATTTT CTAAACAAACTTTGCACAAGACTGGAGTTCTTCCTTCCTTATGCGTTTGATAAATTTGAC CACTGAAACCATCTGGGCCTGGAATTATCTTTGTGAGAAGTCTGTTGAACAACAATTCAA TTTCTTTAAAAATGAAAAGCTATTCAGATTTTTAAATTCTACCCTATTTCAGTTCTGATA AATTGTCTTTTTTATAGAATTGGTGCGTTGCATCTACATTGTCAAATTAATTGGCATAAA ATTGTTTATAATACCTCCTCATATATATCTACATGATCTGTAGTAATACCCCTATTTTTG TTTTATTGTCTTGGCCAGTACAGGAGGAATTCTCTTACTCTCTCTCTTTCTCCTCTCTCT CTCTCTCTCTCTCTCTCCAGTTGACCTTCCATGGCCATGGGTTCTCCATCAGTGGATTCA ACCAGCCACAGGTCAAAATATTAAATAAGGCTGGGGCACCATGGCGCACGTCTGTAATCC CAGCACTTCGGGAGGCCTAGGTGGGTGGGTCACCTGAGGTCAGCAGTTCAAGACCAGCCT GGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGAGGC GGGTGCCTGTAATCCCAGCTACTTGGGAGGATGAGGCAGGAGAATCGCTTGAACCTGGAA AGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGCGCCAGAGTGA AACTCCATCTCAAAAAAAAAAAAAAAAATTAAATAGCAATTAAAAAACACAAAGAAGCGA TATAGCATAACAACTGTTTACACAGCATTTATATCAGGTATTATAAGTAATCTAGAAATG ATTTGTACTACAGAATGTGTATAGTCTATATGTAAATATTATGCCATTTTATGTAAAGAA CTTGAACACTGGCTGGGGTGATGTTCTGGAACCAATACCCCATGGATACGGAAGGACAAC TGTATATACACCTGCATATATAAACTATATATTTACAAGGCCAGAAATTGTTGAGGGTGC CCAGCACAGTAACTGGCACGAAGTAAGTCATCATAATAGTTGTATTAGCGTTGCCTTCAT AGGTGGTGATTTGGAGAATCTATTCTAGGTGGGTACAGCAATGGAGGCTTTGGTCCAGTT TGTCTAGGGTCATGGTGGTGAGAAATAGCAGACAAGCCTGAAAGGATGATTTGGGGCTTT CCTTGCCCCAAAGAGAGAGAGAGACAGAAAATCCTTGCACCGGATGATATCAATGCTGTG CCTCTGAATGTCCATTTGGAAAGCCAGTCCTGTGCTTCCAAAAACAGGATATTCAACACC TTGAAGAGGTGTGGTAATTGCACATCTTACTTTTTACGTTTTAGGAAGTCTACAGAGAGT GGGGCTGAAAAGTTTGGGAAGAACAGGTAGGCATGTGGGGAGGGCAAAAGAACAGAAATA ACATGCACAAGCATTTTTCTAGGAAAATTTTAGGGAAAGCTAAGTGATGTAAAGTTACAC TTAAAAGACTACACATTTTCGGCCGGGCGCAGTGGCCGAATCCCGGCAAAAGTAATCCCG GCACTTTTGGGGGCCGAGGCCTGGGGAACACGAGGTCAGGAGTTCGAGACCAGTTGGCCA ACACGGCAAAACCCCGTCTCTACTAAAAATTAGCCGGGCGTGGTGGCAGACACCTGTAAT CCCAGCTACTCGGGAGGCCGAGGCAGGAGCATCGCTTGAAACCGGAAGGCGGAGGTTGCA GCGAGCCCAGATCGCGCCACCGCACTCCAGCCTGGGCGACAAGAGCGAAACTCCGTCTCA AAAACAAAACAAAACAAAAACTACACATTTTCGCACTTTAAGGGCTCAACGGCTGTATTC CCACTCCTTTGCCACTCTCTTTGCTCTTTTCCGCTCTAGAAAGAATTAATGAACTGGATC AAATCTAAGTTCTCCACGTTACAGATGGGAAGCCTCCGGGCCAAGGAGGCCAATGGTTAC ACAAACCAGGTAAGAAAATAAAATATGCCCAGTAAGTTCATAGGACCGGCGGGCTTAGAT TTCGAATGCGCGTGACTCTGTCAACTGTGGACTTAACCCTATGCAGAGATTAGAGGAGAG AATAGTCAAACACGGATAAGTTAACATTTACCGAACAGTCCGTCCTACCCTGGGGTAGGT TTTATTAACAGTCTCGTTTTGCAAAGGAAGACAGCTGCCAGTTGT bcftools-1.21/test/csq/ENST00000256452/ENST00000256452.fa.fai000066400000000000000000000000211467060157400215300ustar00rootroot000000000000003 57105 21 60 61 bcftools-1.21/test/csq/ENST00000256452/ENST00000256452.gff000066400000000000000000000107351467060157400211630ustar00rootroot000000000000003 ensembl_havana gene 21 57085 . - . ID=gene:ENSG00000091181;Name=IL5RA;biotype=protein_coding;description=interleukin 5 receptor%2C alpha [Source:HGNC Symbol%3BAcc:6017];gene_id=ENSG00000091181;logic_name=ensembl_havana_gene;version=15 3 ensembl_havana transcript 209 40452 . - . ID=transcript:ENST00000256452;Parent=gene:ENSG00000091181;Name=IL5RA-004;biotype=protein_coding;ccdsid=CCDS2559.1;havana_transcript=OTTHUMT00000206523;havana_version=1;tag=basic;transcript_id=ENST00000256452;version=3 3 ensembl_havana three_prime_UTR 209 696 . - . Parent=transcript:ENST00000256452 3 ensembl_havana exon 209 783 . - . Parent=transcript:ENST00000256452;Name=ENSE00001908764;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001908764;rank=13;version=1 3 ensembl_havana CDS 697 783 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 5254 5338 . - . Parent=transcript:ENST00000256452;Name=ENSE00000912357;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00000912357;rank=12;version=1 3 ensembl_havana CDS 5254 5338 . - 1 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 7003 7099 . - . Parent=transcript:ENST00000256452;Name=ENSE00000912359;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00000912359;rank=11;version=1 3 ensembl_havana CDS 7003 7099 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 22696 22834 . - . Parent=transcript:ENST00000256452;Name=ENSE00001657506;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001657506;rank=10;version=1 3 ensembl_havana CDS 22696 22834 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 25771 25916 . - . Parent=transcript:ENST00000256452;Name=ENSE00001619473;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001619473;rank=9;version=1 3 ensembl_havana CDS 25771 25916 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 28342 28529 . - . Parent=transcript:ENST00000256452;Name=ENSE00001733184;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001733184;rank=8;version=1 3 ensembl_havana CDS 28342 28529 . - 1 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 28609 28762 . - . Parent=transcript:ENST00000256452;Name=ENSE00001634426;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001634426;rank=7;version=1 3 ensembl_havana CDS 28609 28762 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 32164 32302 . - . Parent=transcript:ENST00000256452;Name=ENSE00001730405;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001730405;rank=6;version=1 3 ensembl_havana CDS 32164 32302 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 33147 33292 . - . Parent=transcript:ENST00000256452;Name=ENSE00001624596;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001624596;rank=5;version=1 3 ensembl_havana CDS 33147 33292 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana CDS 35375 35456 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 3 ensembl_havana exon 35375 35459 . - . Parent=transcript:ENST00000256452;Name=ENSE00002726718;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002726718;rank=4;version=1 3 ensembl_havana five_prime_UTR 35457 35459 . - . Parent=transcript:ENST00000256452 3 ensembl_havana exon 35940 36008 . - . Parent=transcript:ENST00000256452;Name=ENSE00001322495;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001322495;rank=3;version=2 3 ensembl_havana five_prime_UTR 35940 36008 . - . Parent=transcript:ENST00000256452 3 ensembl_havana exon 39022 39163 . - . Parent=transcript:ENST00000256452;Name=ENSE00000997127;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00000997127;rank=2;version=1 3 ensembl_havana five_prime_UTR 39022 39163 . - . Parent=transcript:ENST00000256452 3 ensembl_havana exon 40417 40452 . - . Parent=transcript:ENST00000256452;Name=ENSE00001898297;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001898297;rank=1;version=1 3 ensembl_havana five_prime_UTR 40417 40452 . - . Parent=transcript:ENST00000256452 bcftools-1.21/test/csq/ENST00000256452/intron.txt000066400000000000000000000001251467060157400207200ustar00rootroot0000000000000035931 A AAAC intron|IL5RA||protein_coding 35931 A AAAC intron|IL5RA||protein_coding bcftools-1.21/test/csq/ENST00000256452/intron.vcf000066400000000000000000000006141467060157400206620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 3 35931 . A AAAC . . EXP=intron|IL5RA||protein_coding;type=ENST00000256452:3147143-A-AAAC bcftools-1.21/test/csq/ENST00000263103-INS/000077500000000000000000000000001467060157400172665ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000263103-INS/ENST00000263103-INS.fa000066400000000000000000011701231467060157400220420ustar00rootroot00000000000000>10 10:60272880-60591215 GAGCCCGAGCGCTGCGCGCCCACCATGGCCGCCCAGGGAGAGCCCGGCTACCTGGCGGCG CAGTCGGACCCCGGCTCCAACAGCGAGCGCAGCACCGACTCCCCAGTGCCCGGCTCCGAG GACGACTTGGTCGCCGGGGCGACCCTGCACAGCCCGGAGTGGAGCGAGGAGCGCTTCCGC GTGGACAGGAAGAAACTTGAGGCCATGTTACAAGGTAGGCATCCCTCGTGTTCTCGGACT CTCCGACTGAGCCTCTAACTCCTTTTCGGACATCCCCACCGCGCGCTCCGGCGCCCGCTA CTCCAGCCTACGGCCGGCCGGTTTAGCTCCAGGCCCGCTCCCCCGCGGAGCCGGAGGACA CCCAGGGACTGGAGACTTCGCGGGACTCCCCACCCTTCCACGCCTCTCAGATTTCCAGGC GCTGGGGGCCCTGTGCGAACTTGACTGGCTTCAGAAAAGCCGAAGGCCGAGTTTGTACTG GCGCGCCCAAGTTGCGTTCTGGACTTTGGAGATGCCAACTTTAGCCCGGACACCTGGGCT GTGCCATCCGGACCACTCGGGCCGCACAGAGTATGCGTGACCCTCCCCATTCCCTGGCAG CCTCGAGTTCTGTCTCTCTCCGTCTGTTTCACTCTCTCCCCTTGTCAGTATCCACTTCCT CCAGCTGAGGGGCCTTGTCTCACTATTGGGAAACGCTCTGCAGATGTCAAGGCTTAAGAC AGGAGCTCCCGCCCCCACCCCTGTGGTCAAGGAGGGCCAGGATCGGGGTGAGCAGCCAAA GCGAGGGGGGAGTGTGGAGGCAGTGCTGCTGTGTTTGAGGACAGTGTTCATCTCTTGACA GGCTTATAAAACACATCTTGAGTTACATTCAGTCCATAAAAATCTTCCTATGCTATGGGT GTCTGACTTTGTCTTTCACAACTTAGAATTATTTTTAACTCTTTAATTTCTTTGGGACTT TCCCAGGTAGAAAATCTTCAACCATACTGGACCGAAAACAGATTCTGATTTATAATACGA GTGTTGGAGTGAACGTCAAAACGTCCAAGGTCATTTTGACCTTTCTTAAAACAGATAATT ACTAGCCTACCTGTAGCCACCGATGTGGCTCATTTCCCACATCCAAAGAGAGAAATGAGT TAGTTTGAATGACTGTTATTCTTAAAATACGTGTACGGGACCAGGCGTTAGTCTCACTTA GGGCGCTGGTGAAGATTCATTCAGTAGCTAGTGTTCTTTTATCATGGAGGAGTTTGGAGT TTTTCAAACGTTATTTGTGGCTTTATGCATAACTTACTTTGACTTTATCAGTCAATGCAT CGCAGTATGGGAATGATTTAGCCCTCTGTGGAAATGCAGTGGCTTTTTAGAACAATTAAG CAGGTTATTTTAAGAGAGAACAACATGTTTTCCAAAACAATAACTTGGTGGAAACAAATA GCAAGAGTGTTTGGCAGACGTTTTTTGGATGTGCTACAGGCTTTCCTCCCTTGTTGCTTA TTTTTATTGACAAACATCCCTAATGTGTGTCATGTCTTTCTCTGTCTCTCCCCTTCCCTC TCTTTTTTTCTCAAATTATGTAACTTTTGAGGACAGTTACTTCTGTGATAAACTCTTCAA GTAAGACCGTTATAAGATAGATTTGGAAATTAAAGCCCCAGTTGCATTTCAGTAACTCAT TTCAGTTATTTCGTCTGTTCTGTGGTTCTTTTTGCCTAGTTTATGATTATAAAACAAAAT ATTAAATTTATGTCAGGCATATATTGTGAGATCGTTTGGAATGAACTGATAGTAGCACAT ACTCATCCTTTTCAACCAGCTTTCAGTTTTCTACATTAGTTTGGAGTGATATGAAAGAAT GATCTGTTTCACCTGCGCACAAACAAGTAAGGACAGTGATGTTAGCTTCTGGGAAGTTCA AGTGTATAACCTGAGCTTTAGAAGTGAATTTCCTTTTTTGATTTAATTCATTTTCACTTC GAATAAAATGAAATTTTGAGGAGACTTTTTGAAAATTTGAAGGCTCTTTTGTATTAATAG ATGTGATACTACGATCTGAGACGGTTTGAAATTGCTTTGCAGTAATAGTTTCTTTTACAG AAAGTCTTAACATCTCTTGAACAACCGATATACAGTCATGCAGTCCATGCTTAAGGACTA CGACTGGGATACCTTGTTAGAAATGTGTCCTTAGGCATTTTCATTGTGCAAACATCATGG AGTGTAGTTACACAAACCTAGGTTGTGTAGCCTGCTACACCTACTACCTAAGCTATATGG TATAGTCTATTGCTCCTAGGCTACAAATAATGTTACTAGGCTACAAGGCGTGTTACTATA CCCAATACTGTAGACAGTTGTGGCACAGTGGTATTTGTGTATCTAAATATATCTAAACAT TGGAAAGGTAATGTGTTATGTTACTATGGCTATGACATCACTAGGCGATAGGAATTTTTC AGCTTCTTTATAATCTTACGGGACCATTGTAGTGTATGTGGTTAGTTGTTGACCAAAACA CAAGTGTGAGCACTGGGATCACTAATACCTGGGTTCAAAACTCTGTAGGATCTCAGGAAA GTTGCTAGGCCTCTCTTTGCCTTCAGTTTGCCCATCTGTAAAATGGAGCTGATACTAGGA CCTTTTAGGTTTTGGGAGAATCGAAAGAGATAATGCCTAACAAGCTAACATTTGCCCACA GTGTTTGGTCAATGATAAGAACTTAATGAATATCTGTTGTTATTATTAATAATAAATATT GCATCATGGATTAAAAGGATTTCCAGTGCCTACCACAATGTATGAAATATAGTATATACT TAATAAATAGTTGGGGAACAAAATAATTTTGCAGGTTCATAATTGCAGAAGTAAAATAGA AACTAAAGAAGTAAGTCTATCAAGTCAATAAGCATTCTAATATTGTTAGATATTCTTGGG TGGAAAGCTTTTTATTTGAAAAGTGCCAAGTAAGTAAAGTCTGTATTTGAGTTTTCAATT ATTGTGAATTTGGGTGTGCTATTTTTCTATTTACAATTGACTTAAAATAGGTACAGGTTT CCAATTTAAATCAGGATAAATAAGATTATCTGCCTTTAAGTATTCAGAGTGCAAATTGGT GATTATAATGCTTGGAATTTGTTTCCAGAGAGACTGTCCTGGGGGCAAGTTAATCTTTAA TGAGTTGTATTTTTATTAGTAGATAAATTCTTCTACGCAATGGACCAAAAATTCAGTGAG GTTAATATATGGGCAATAGGGTAGTAGTCAAATAAATGAAATACCATTCTTAGATGATCA TTAAAACTTAAAAGAATTGTTGCAGATAAAAACCACCAGGCCAACAATGTAGGGAAATAT CACTCTTTTTTCATGGTTTTTTACTGGCAGGTTGGGGTCTAATTACTACTTCGAAACAAC CATGCAGAGTATCTGATGTTTTTGCTGTAAGTGAAGATTATCAGTTTTATTAGTTTACAG TTTTATAAATGGAAATTTATTTTCAAGTTTAGGTTTTTGATGGGTGTGGTAAGTCTTGGA ATGAATACCATAGACAGCATTTTTAATGATAAAGAAAATCCTTATATAATTTCTTTATTT AATACTGATCTTCAAATGTAAATTTCATGCATCATGTGAAATAATAGTATTGATTTATGT AAGCCAATTAAATTTTAGTTAAATTAACTCAAAGTTATAAGTTACATATCATAACTCACA TTAACTCAACTGAGTTATCAGGGAGGAAAGGGAGGAGAGTGTTATAGCAGGAAGTCTGGG AGAAAGTAAGAAATAATTGAGTCAAGAGAATCAGAGATACAGTCTTGGTGTTTGCCAGAG TACTGAGGCAATCACAGGATTCCTATATTAATACTTTTCTTTTTTAAAGTATTTTTCTTT GTAAAAACATATATGTGTACTATAAAATTAAAAATTCCCATATATAACACAGCACTTCAA ATTATTATTTAAAAAAAATTTCCCATATAAAATTCAGAAGCATAGGTATTTTCAAAGTTT GGGAATCCCTTCTTTCAGTAGAGAAAATGGTAAGTGTTAAAAAGTGGGACCTGTGGTGGG GAGGAATGGCCTATTTTCATGAAAGGAGATTGACATCTGGTGGGATTTTATGATACTGCT GCCAAAGACTTTAAGAACCATGTTGCATTTTTGCAGTGATAGGCAGAACTGGGGTCATTT GCTACTGCTCGGTTGAGTAGCAGAGTTAGCCACTGAAACAGAGGTTGTTGTACATCATTG ATTAACAGTAGGAGCAGCAACTATGTTATCTCTTTAATTCAGCAAACTTTAGTGGATTTT TAAAATGATTTGATGAACAGATAATAATTTAGACTTTTTTCATGAGAGCGGGAAGAAATA TGAAGCCAAAAATGTGTGAAAATGGGGGAGTACTGAAAGTGAAGATAAAGAGTAAAGCTT AAATAAACAGAGTTTTCTAGCTAATGCTTGATCAAGGCTAATAAACAGCAAAAACAAATC AAATACATTTATGAGCTTAGAGATTAATAGCACAGGGCTGTGGGCCAAATCTAGATTTGA ATCTTGATGCTACATTTTAATAGGGAGCTTGGGAGAATCCATCACTTGGCGACCTCATTT CTCAAATGGGGCAGTTAATGGTAGTACTTACCTCCTGAGGTAGTTTTGAAAATGAAGAGG AAAAAGGTGTATGTAAGTCATCCCAGTGCTGGCAACATAGGAAGTGCTGAATAAGCTAAT AACAATATTCACAGTAAATCATTATGTATAAAATGCACTTTCTTATATTGATCATGAAAA TCAAGTATATTGGAAACTTTAGTTTGGTCTTAAATTATCTTACGATTAATGAACATGCAC AGCTATCTAAATATTATTATTGGCCTCCCTGGTAGCTTGCCATGTGTTGAGTATACTTGT AAAGGTGGGTGGGTAAATACTAAGTAAAGCTCCATTAGACATGAGTGTGGAGTTCTAGAT TTTGCTCAGGACGAGAGGGCTTTTCACCCTTTTTAGTTGTAAATTGTTCTTGCTTTGAGT ATTTTTCATTATTTGACTGGTCCTGAGCCATTCATTTCTAGTATGGTTTACTAAAGACTA GCAGCGAAATCAGTTAATCTCTCTTCTGGTTGTAAGTTGCTCTGAATTTGAGTCATTCAT TGGTGTGTAGAAAGAAGGTTTTTTGAAGAAAATACTCTGCCTGGGTTAACATGTTTCATT TGCTCACCTGTAAAATGGGGATAATAATAGTCCTACTTTACGGTGATATTGTGAATGCTG AGTGTGAGAATGTATGTAATATGCTTAGTTCAGTGCCAGGTTGATGGTGCTTAATAAACA TCAGTTCAGATGCAGCAGTACTGTCTCACATGATGGATAAAGATTTCAAAACACTAGAAA GCAAATACTTGCCAAGTCTTTTTTTCTTTTTTCTTCTAATTGCATGTGAATCCTTTGTGT ATGTGTGTGTTGGGGGGGGGGGGGTGTGTTTGATGTGTTTTAGTGAAAGTCTTCCTCAAA AAATTAGAAAAGTTTGTTATGACAATTTATTTGATCCAGAGAGCATAGTTGCAATTAAAA TTGCTTTATAGATTAAGTGAAAAAACACATCAGAGGTTGTATAGCTTGGCAGTAAAGAGC CCAGGAGCTGCTTTCAGACTAACTTGGATTGAGGAGGTCCTCACTTTGCTTCTCGTAGAG TTCCGTGAGGATGCACTGAGAGGGGCAGTAAAACCTCACGCTCACGGGCATGGAGCAAGC ACTCTCAGTCACTTATCTCTATGAAGACTTGGAGGGTTTTGGTGAAGTTGATCATTGATA AATACATAGCTAGAGAGGTTTGTTATACCAATGACTTTTACAGGCAAGAATGTATTTGGC TGCGACTAACAGGAAACCTGACACAGAGTGGCTTAAACAAGCCAGGGGTTTGTCCTTCTC ACCTAATGAGAAGTCTGGGGCTAAGCAGTCCAGGCTCCAAGAGCTGCTCAAGGGCATCAG GAGCCCCGTGTCTTCCCTCTTCCCTGCCTCCACCATCTTCAGCCTGTGGCTTTTTGCCTT ATTTTTGCACTGTGGCTGTGGCTGTGTTTTGAGGTGTGTCTGGTTTATGCAGGAAAAAGG CGGAAGAAGAAAAATTATTTTCTCTTAGAGATTTTGCATTTTTATGTGACAAAGAATTCT CTCTCCTGGAACTTCTGTCTGTACTTCTTTGGCCACCTTTTGCTGCAAAAGACTCTGGGA ATGTATCTTCTTTTTCCAGCCTCACTAGTGGAAGTAGGCAAAGAAGAAGGGGGTCAGAAT GGATGCTGAATGTTTTACCCCATATTTTCCTCACAGTGGGCAAAGTGGAGGAGCATTAGG ACTCAAAATTGCAAATTGTGACTGAAGTCAAAGCTTACCTGTATTGGAGACTTTGGACTG TGCTGATAATCTGTAGGAACTTATGTTATTCAGTAACATTATATATCAGTAGAATTTCTT TCTTTCCTTTTTTTAAATTATAATTTTTTTTCATCAGGCAGCCCCTGAACCAGAATAGGT TCTGAGAGGCTCCCTAGAATTTCTTTCTTGGCATAGTCCAGAAGTAAACCTAAATACCAA AGAGGAAACCAACTCTGATCATCTAAAGCTCTTCTCATCTTGTTACTCCTTTTATGAACA GAATCTAGGACCACTGAGTACTGGAACTATCTCTAAAAATTCTCCATTGTTTTCTCCATG TCAAATGTTTTTTTTTCCATAGAAAATTACATGGTACAATAAAAATGCTTATTTCACTTT TTATTATCTTAAGATATCTTTTCTGTCCTCCCTCCTCCCACTGTCCACACATGTCAGATT TGGTTTAGAATTGACAGGTTCAGTGTAGTTCATGCCTCGCCCTTTTGGCTTTTCATAGAT TGGTCACTTAGGTATAATCTGGCCAACAAAGCCAGAATTTGTTCAGAACCGTTTTGGAGA CAGTTTGATAGAATTATCATCCCATGTTTTGTCGTCTGAAATTGTCCAAAATAGTGAGCT AATAAAATAGACCAGTTGACTCATTCTTAGTTCGTTTTAAGATACTGTTCTTACTTAAAA AATACATAGGGTAATAGTGACCACATATATTCCTTTATATGAAATATTTAATAAACTACC AGGAATGAGGCGCAATTTTATTGCTAATTTATAGTGGTTTTGGTGTGTGGGGATGATCTT GGCAAGAAAATCTTGTTATGCTGCAAAAGCCACCAAATTCAATGTCTAATCCTTATCGTA CTACCATCTAGGGCAGTCTCCAGAGAGCACAAAACCATCATAGAAGCATTGTGGGTGCTA TACATTTGTAAATCCTTTTCCTACCTATCAGGCTACTAATAGCTGTGGATGATGAAAATG TTTGTATTTGTAACAAGTATTAAATCTTGTTCCCATTTATGATGCTGGCATATAAAAAGA TAACACTTTCTAGGTATCAGGTGGTTTCCCTGTTATAGTGAGAATGATAAACCACATATT AGTCTGCATATTGAGTTGATCTGGAGCTTAACTGTATCTCTTATATAGAAAGGTGATTAA ACATAGGATTTGAAAATTAGCCATTGCTGTTTTTTCCCCCTCGATTTTAAAAGTAATACA AACCTATATAGAATACTTGAAAGTATAAACATAAGTAAAAAAGAAAAACCAAGTCATCCC TAACTCCAGAATCCAGCAATAACCACTGATGATATTTTAGGAATTTTTTTCCTGGTCTTT TGAAAATATGCCCACACATAATTTATTTTTGCCATGCATTTTGAGTTTGTACCATATGTC AGGTGCAGTGTTGAGCTTTGGGGATGCAGATGAAACCAAAAGAGTTACTGGCCCTACCCT TCTGTGACTTAAATTCTACACTGGGATCATACCTCCTATCTTTTTCACTTAGCGTTGAAT CATAAGTATTTTCTGTTTCATTAAAGGTTCTTGAAGAACATGGTTTCCGGTGTCTGTATA ATTCTTTTGTTGTAGTATACTTTGTTTAAACACTACAACATTTTAGAATATTTTTAGGTG GCTAGACAGTGGAATGAGTCCAGTGTTTCTACTCAAACTGCCCGGGATTCAGATCCTGAT TATTAGCCATGTGGCCTGGGACAAATTAATAACTCATTTGGCTTCTCATCTCTAAAATGG AGATAAAAAGTATCTATCTTCTAGGTTGTGAGGATTAGAAATACTGTATCCACAAGTGCC AGGTGCGGAGCAGGTACTCAAGATATGGCAGATGATAAATATTTAGCCCGCTGTCCCAAC CACTTCTGCCTAAAAGCCTTTTATGCATTTTTTATTATTCTCATAGGAAAAACCTTATTA GTGAAATTTTGGGGAGCAAAGGACATGGAAATTTTAAGGTTCCTGATCAATTTTGCAAAA TTATTTTCTGGGAAGTTTTGCAGGTTAGGCAGAAGAGACAACAAATCTGCAGGGTAATCT GCTCCTTATACCTGCGGTTCCCACAGTCCATTATTAGAAAGCAATTGAATTACCAATATA AAGTTAGATCTCCGTTTTGCCTTTTTTTGCTGAAAAATTGAAGTGAATTTTATCTTACCT GCTTAGCATGTTTGTGGATCAGTATTTTTTAAAAGTTGTGGGCATGAAAATCAGCCAGGG AATGTGGTGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGGGAGTACACT TTGGCCTTCCCTCTCAGATTCCAACTTTGTAGGTTTGAGAGTGGTGTTGGCAGGATTGGC ATTTTGGAAAGAATCTTTTGTGAGTCTAATGGAGATGGTCCCAGGATCACACTTTGAGAA ACATTGCAAGGTGGTTAGAGGATGGTGAAATCATTGAAGTTAAGAATCAGACTCTTTTCT TTCTTTGATTTCCTTTACCCTTGAAGCTAGTACTTTTTCCACATTATTAAACCATCTTGA AGCATTTTAGTCTGGGAACATAATTTATAACTGGTATGTTGTTTATAGTGGCTTGTTGTA AGGGACTTGGGGGAGGAGCACAAATCTATATATTCTTGCGGAGGGCAATATTGTCATATT GCACAGTAGGCTCACAATGCATTTGGTTTTCCTGCAGACTCCCATTAAGTTAGGCATAAT AGATACCTATGTAATATATTATGAAATAATTTAAAAACACACTTTTCATTGTAGAAATTT TTAAAGCAATACACTCCTTAGCAAATGTAAAAGAACAGAAATTATAACAAACTGTCTCTC AGACCACAGTGCAATCAAACTAGAACTCAGGATTAAGAAACTCCCTCAAAACCGCTCAAC TACTTGGAAACTGAACAACCTGCTCCTGAATGACTACTGGGTACATAATGAAATGAAGGC AGAAATAAACATGTTCTTTGAAACCAACGACAACAAAGACACAACATACCAGAATCTCTG GGATACATTCAAAGCAGTGTGTAGAGGGAAATTTATAGGACTAAATGCCCACAAGAGAAA GCAGGAAAGATCTAAAATTGATACCCTAACATCACAATTAAAAGAACTAGAGAAACGAGC AAACACATTCAAAAGCTAGCAGAAGGCAAGAAATAGCTAAGATCAGAGGAGAACTGAAGG AAATAGAGACACAAAAAACCCTTCAAAAAATCAGTGAATCCAGGAGCTGGTTTTTTGAAA AGACCAACAAAATGGATAGACCGTTAGCAAGACTAATAAAGAAGAAAAGAGAGAAGAATC AAATGGACACAATAAAAAATGATAAAGGGGATATCACCATCGATCCCACAGAACTACAGA CTACCATCAGAGAATACTATAAACACCTCTATGCAAATAAACTAGAAAATCTAGAAGAAA TGGATTAATTCCTCGACATATACACCCTCCCAAGACTAAACCAGGAAGAAGTTGAATCTC TGAATAGACCAATAACAGGCTCTGAAATTGAGGCAATAATTAATAGCTTACCAACCAAAA AAAGTCCAGAACCAGATAGATTCACAGCTGAATTCTACCAGAGGTACAAGGAGGAGCTGG TACCATTCCTTCTGAAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAACTCAT TTTATGAGGCCAGCATCATCCTGATACCAAAGCCTGGCAGAGCACAACAAAAAAAGGGAA TTTTAGACCAATATCCCTGATGAACATCGATGCAAAAATCCTCAATAAAATACTGACAAA CCGAATCCAGCAGCACATCAAAAAGCTTATCCACCACGATCAAGTTGGCTTCATCCCTGG GATTCAAGGCTGGTTTAACATACGCAAATCAATAAACGTAATCCAACGTATAAACAGAAC CAACGACAAAAACCATATGATTATCTCAATAGATGCAGAAAAGGCCTTTGACAAAATTCA ACAAAGCTTCATGCTAAAAACTCTCAATAAATTAGGTATTGATGGGACGTATCTCAAAAT AATAAGAGCTATCTATGACAAACCCACAGCCAGTATCATATTGAATGGGCAAAAACTGGA AGCATTCCCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTCTCACCACTCCTATTCAA CATAGTGTTGGAAGTTCTGGCCAGGGCAATCAGGCAGGAGAAAGAAAGAAAGGGTATTCA ATTAGGAAAAGAGGAAGTCAAATTGACCCTGTTTGCAGATGACATGATTGTATATCTAGA AAACCCCATCGTCTCAGCCCAAAATCTCCTTAAGCTGATAGACAACTTCAGCAAAGTCTT AGGATACAAAATGAATGTGCAAAAATCACAAGCATTCTTATACACCAATAACAGACAAAC AGCCACATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGAGAATGAAATACCTAGGA ATCCAACGTACAAGGGATGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTCAAT GAAATAAAAGAGGATACAAACAAATGGAAGAACATTCCATGCTCATGGGTAGGAAGACTC AATATTGTGAAAATGGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATC AAGCTACCAATGACTTTCTTCACAGAATTGGAAAAAACTACTTTAAAGTTCATATGGAAC CAAAAAAAGCCCGCATTGCCAAGTCAATCCTAAGCCAAAAGAACAAAGCTGGAGGCACCA CGCTACCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTACTGAT ACCAAAACAGAGATATAGATCAATGGAACAGAACAGAGCCCTCAGAAATAATGCCGCATA TCTACAACCATCTGATCTTTGACAAACCTGAGAAAAACAAGCAATGGGGAAAGGATTCCC TATTTAATAAATGGTGCTGGGAAAACTGGCTAGCCATATGTAGAAAGCTGAAACTGGATC CCTTCCTTACACCTTAATTCAAGATTGATCAAAAATTAATTCAAGATTGATTAAAGACTT AAATATTAGACCTAAAACCATAAAAACCCTAGAAGAAAACCTAGGCATTACCATTCAGGA CATATGCATGGGCAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAA AATTGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCAT CAGAGTGAACAGGCAACCTACAGAATGGGAAAAAATTTTTGCAATCTACTCATCTCCCAA AGGGCTAATATCCAGAACCTACAATGAACTCCAACAAATTTACAAGAAAAAATCAAACAA CCCCATCAACAAGTGGGCGAAGGATATGAACAAACACTTCTCAAAAGAAGACACTTTTGC AGCCAACAGACACATGAAAAAATGCTCATCATCACTGGCCATCAGAGAAATGCAAATCAA AACCACAATGAGATACCATCTCACAGCAGTTAGAATGGCAGTCATTAAAAAGTCAGGAAA CAACAGGTGCTGGAGAGGATGTGGAGAAATAGGAACACTTTTACACTGTTGGTGGTACTG TAAGCTAGTTCAACCATTGTGGAAGTCAGTGTGGCAATTCCTCAGGGATCTAGAACTAGA AATACCATTTGACCCAGCAATCCCATTACTGGGTATATACCCAAAGGATTATAAATCATG CTGCTATAAAGATAACATGCACATGTATGTTTATTGTGGCACTATTCACAATAGCAAAGA CTTGGAACCAACCCAAATGTCCATCAATGATAGACTGAATTAAGAAAATGTGGCACATAT ACACCATGGAATACTATGCAGCCATAAAAAAGGATGAGTTCATCTCCTTGGTAGGGCATG GATGAAGCGGGAAACCATCATTCTCAGCAAACTATCGCAAGGACAGAAAACCAAACACCG CATGTTCTCACTCATAGGTGGGAATTGAACAATGAGAACACGTGGACACAGGAAGGGGAA TATCACACACTGGGGCCTGTTGTGGGGTGGGGGGAGGGGGGAGGGATAGCATTAGGACAT ATACCTAATGTTAAATAATGAGTTAATGGGTGCAGCACACCAACATGGCACATGTATACA TATGTAACTAACCTGCACGTTGTGTACATGTACCCTAAAACTTTAATAATAAAAAAAATT TTTTAAAGCAATACAAGGAAGCTTTTTAAAAAGAAAAATAATCGTCAGTAATCTCACCAT CCTAACAACCATTTTCATTTTTCTGCCTTGAATTAGAGTTTATGTAGTTGCTGGTATAGT ATTTACTGCTTTGTATTCAGTATTTTAATCTATTAAATGTTTTCTGTATTTCTAAGCAGT TTTCAGAATTCTGTGGTTGAATAATAGTACATTTGGTTGAAAAAAATTTTTTATAGTTAT GAACTACCTAATAACGAATGTGATTACATGGCTTTTTTTTCTTCGTGACTGTATTCTGAG GAAGAAATTTGAGGAATCTGAGTACTGAAGAATGATGGTAGTTGCAAAAGCAGCAGCCAA TTTGTATTATCTCTTACTTTGTGTGGGACATTGTCTTTGGTGATTTATGCCTGTGCGGTC ATCTCAGCTTCTCAGCAACAACTCATGACATACAGATGCCCATTGGGATCTGTACTTTAC AGAGAAAAAAAAAAGCTGTAAACACTTTAAATTTGGAGCCCTGATTTCTTTTTGGAATTC CAAGTAGACCTAGACACTAGTTTTCCAATTAGGGTTGTTGTAAGGTCTAGACTTTTGTAT GTTGTGGAGATGTATCATAGCTGAGTTTAGGATGACAAACCACCCTCCCGAATAGGTTAC ATTGTTTCTTTCTTTTTTTCTTAATTATACTTTAACTTCTAGGGTACATGTGAACAACCT GCAGGTTTGTTACATATGTATACATGTGTCATGTTGGTGTGCTGCACCCATTAACTCATC ACATGTGTCATATTGGTGTGCTGCACCCATTAACTCATCATTTACATTAGGTGTATCTCC TAATGCTATCCCTCCCTGCTCCCCCCACCCCACGACAGGACCCAGTGTGTGATGTTCCCC ACCCTGTGTCCAAGTGTTCTCATTGTTCAATTCCCACCTAAGAGTGAGAACATGCGGTGT TTGGTTTTCTGTCCTTGCGATAGTTTGCTGAGAATGATGGTTTCCCGCTTCATCCATGCC CTACCAAGGACATGAACTCATCCTTTTTTATGGCTGCATAGTATTCCATGGTGTATATGT GCCACATTTTCTTAATTCAGTCTATCATTGATGGACATTTGGGTTGGTTCCAAGTCTTTG CTATTGTGAATAGTGCCACAATAAACATACATGTGCATGTATCTTTATAGCAGCATGATT TATAATCCTTTGGGTATATACCCAGTAATGGGATTGCTGGGTCAAATGGTATTTCTAGTT CTAGATCCTTGAGGAATCACCACACTGTCTTCCACAATGGTTGAACTAGTTTACAGTACC ACCAACGGTTTAAAAGTGTTCCTATTTCTCCACATCCTCCCCAGCACCTGTTGTTTCCTG ACTTTTTAATGATTGCCATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTT GCATTTCTCTGATGGCCAGTGATGATGAACATTTTTTCATGTGTTTTTTGGCTGCATAAA TGTCTTTTGAGAAGTGTCTGTTCATATGCTTGGCCCACTTTTTGATGGGGTTGATTTTTT CCTGTAAATTTGTTTAAGTTCTTTGTAGATTCTGGATATTAGCCCTTTGTCAGATGGGTA GATTGTAAAAATTTTCTCCTATTCTGTACGTTGCCTGTTCACTCTGATGGTAGTTTCTTT TGCTGTGCAGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCAAATTTGGCTTTTGTTGC CATTGCTTTTTGTGTTTTTAGTCGTGAAGTCCTTGCCCATGCCTGTGTCCTGAATAGTAT TGTCTAGGTTTTCTTCTAGGCTTTTTATGGTTTTAGGTCTAACATTTAAGTCTTTAATCC ATCTTGAGTTAGTTTTTGTATAAGGTGTAAGGAAGGGATCCGGTTTCAGCTTTCTACATA CGGCTAGCCAGTTTTCCCAGCACCATTTATTAAATAGGGAATCCTTTCCCCATTTCTTGT TTTTGCCAGGTTTGTCATAGACCAGATGGTTGTAGATATAGACCAATGGAACAGAACAGA GCCTTCAGAAATAATACCACACATCTACATTGCTTCTTGAGTGCCCTGCTGAAATGCAGA GGAGCTTGGTGTCAGGCTCGGGTGGGTTAGAATTCTCAGTGAGAATGCAGGTGTTGCAAA GCTCTGCCTTCTACTAGCTTTGGTTATGCTTTCTCAGTTTCTCCCTTTACAAAACAGAAT AATAATATGTCTCATGTAGGGTTATGATAACATTTGTAAGGCTGGCACACAATTGGTGCC CTGTAAATAGTTGGTATTTTTCAAATTCATATTCTGTTCCTCTGTGGCATCTGGCCCAGA GCTGTGAAAATATCTGGACTGTGTTTATAGAATAAATGACCCATGATGGATCTGGATTAA AAAGTTTGTTCATTTTGGGCTAGCGGACCTGGCATTGACCTCATGGAATGGAGCTTTAAA GCAAAGTCACGTGCTTGGCCTTAGGAAGTGCCAAACAGTTCTGCCTTACCCAAGTAAGGC AGAGCAGTTCTCCATATGCAAGATGATCTGTCTTCACCCTCAATCTAGGCCGTATGTAGA ATGTTTTACTGTTAGTGATAGAACATTAGTGTGGAGTTTTGAATGAGGATATGCAAAACT TAATTCAAGCGAGGTTAATGTTAATTATATTTGTATCTAATCTGGATTAGTTTTATAAAT CGAAATTTGTCAAGGTTAATATAATTTCAGTTTATTTCATTGCCGACACTGAATTATCTT GTTCTTAGAATAATATATCTCTAGATACTTGTTTAAATGTGATTTCAAATCTTCTCAGAT AAGAGATAATCCATTCTCAAAATTAAGAATAACCTTTTATGTTAGCTTGCTCACTGCACT AAAATTATCATTGAGTTATTTTGAGTTAGAGGGAAATAAACCACTTCTCCCCACAAAATG TTGATTAGGAATTAGGTGCCCTGAGTTCATGACCCAGTCTTGCCACTGACTTCGCCACCT TGGACAGCCTCTCAGGGTTTTGGATTAGATGCCCCTTAAAATCTCTTTCAGTTCCAGTAT TCCGGGTCTTCTGCACAGTAAACAATACAAACCCAATGGTACTTTGAACGTGGTGTTAGA AGCTGAGTTGGTTCTCCATACATGAGTAGCTTTGGTAGGGATTTGCCTTGATCTTTACCA CACCTGAGCATTCACAGCAAATGGGAAATGTGGTAGAAAGAGAGGATAGTTAAAGTGTCT CGGCTTTGGAGAAGCAAGTACTTGTCAGAGAGCTAACCACAAGCTTTGTTTTCTAACATC TTGGCAGTCAAATTTGCAACACCCTGAATTCTGTGGGCTAGAGCTTAGCTAATTTAAGAT TTTCTATGGTAATTGAGCAGAGATTACAGTGTAAATCATAGTTGAGACTTGTTGGTGTTA ACATACTTGTCTAGGTGAACAACAGATTTTATGCGTCTTCAAGTAGGATCTTTTTGTCAC ATTTTCCTTTTCCTCTGCTAACATGTCCAGCTATCAAGCTTCATGTGCCAGTATTGATAT CTAGCATCTAAACCACTAGAGTTGCAGGGCAGGAAAATGTAATGTTGTGCCTTAGGGTAA AATTTCAATAAAAAATACATCTGTATCTGTCCAGATTTCAAGTATTTTCAGAATTGTTTT AATTGCTTGTTGATTATTGAGAACTAACACAGTATTTCTCTTATTCTGCGCAGAAGACCA CTAAATCTTGTATTATCTATGTTCTGAGTTGATCCCTTTATCATGAGCTTTTTCTTTTGT TTGTTAAAAGCATCACTTAAAGCAAAGGCAATGTTTTGGTAAGATTTTATCTTTTTTAGT TATTTCATATAATGATTTAACTTCAAGCCAGAGAAATGTGTGTTTGGCTTGAGTCTTGCA GGAGGAATCATGTAAAGACATGTTTATTTTAATCTGGGGGGAATTTTTTTTAATTAGAAC TTTTTATATGGGAAAAGAAAACCTGAGATTGTTATAGATCTATAGCGTTTTTCTTCAGGG ATCTATAATTTACTAAAACATTGTTGGCACTTATTACGTACACAGAAAGATCACCTTCAA AAATATATTTACTATCAGTAAATGGATATCTGAGATGCATTATCTAAATAGAGCATATTT GACCAAGTCTAAAAACTGGGCTTTAGCAACAAAACATTATAAAAATGGATCTGGATTTTA AAAGTTTTGCATAAATGATTAGCTTTCAAGCTTGTGAAAGTTTTTTTTTTTCATTTTAAA TCATTTGGGACTAGTGAGGCCATCTACAATGGGAAATTGTTGCATGTATTGGACAAAAAT CATGAGTGCATATTATGGGACTGCAGAATTAAATGAGGCCCTTTACCTTTAAAAGGAATA TAATCTAGTGGAAGAGAGGAAACGTATCTGTATTTTTTAACAGAAAACAAAAGGAGATCA CGTAGAGTAAGGCCCTGATTAATGTACATCATAGCCTGGGTCACGTACCTCCACCCCACA AGACCAAGAAGTGAAATGAGGGAATTGAAGAATCAAATAGAAAAAGGCAAAGCCAATACA ATGATGCACTATCTAGTTTGTTACTTCTGAGGATGACTACTACTTCTGGTGAGGCCCAGA AGCTATATCCCTAAATTGTCCACCTAAGGAATTAAAAAGAGAGGCATTGGTCTGTCAGCT TCTGTTCCCTCCTTGAGGAGAGTCAAGGGTTGCCTTCTGGGGCCTGCCTTTCCTGCGATT CTGTGTTAATACACTTAAGACTTAGACGTATAGATATCTAACAAGCTCCTAGGGAAGTAA TAAAGAAGTATGTTTAGTGTAAGATTGAGATGAGACATTGTTACCCCAAAGTGGGTTGAT ACCTATGCCGAACTGTTTACTGTAGCCTCGCTGGAATCAGAGATGAAGGTGAGATGGTAT ATAAGATTGTGTGTCCAGTACAATGTCTTTATATACTTTAAATGCAAAAAAAAAAAAAAA AAGAAAATCAGAAAGGGAGAGGCGGAAATGGACGTTTAAGATATTTCATACCTTTGTTCT AAATCAAAGAAACTTCCTTACTGTAAATTCTTCATGTAGAGAATGCTTTATGAGATTACA AAAATAAGCCTGTCTGCAGTCAGCAAGATGGAGGAATAGGGAGCACCAGACTTCTACCCC TACAGAAATACTGACTTAACAATATGTGGTCCAATAAAGCCTTTATGAGAAGGCCAGAAA TCACTTATGAAGTCACAGAACTCCAGTTTAAAACCAAGAACCATGGTTTTGAAACAGGTA AGAAAAGCTGTTTCATTTCATCTGAGTCGGCCCCTTCCCCAAGCCACCACAGCTAATGAT GAGGAAAAAAAGTCCAGTGACTGGTTTCTCCCTTGGGAGAAAAAGAGTAAAATGGAATTA TGTCCAATGTGCTGGCTTTTTGAGACTACTCAAGTGACTGGTTTCTGCCTTGCTTGACTT GGAGTGCTGATGAGGAATAGGCATACTTTGATTGCCTGGGGACTGCTGAGAACAAGAGAG CTCAGCGGTTGGTGGCAGTACCAAAATACCCGTAGTACTGCAAACAGACACCAGAGGGTG CAAGAGACTGTAGACTCCTGAAAAAGAAACCAGAAAACTTTGTCTGGTTGTGAAATTACA CACATAGGCTCAGAAAAAATTCATCTCTGTAAAAGGTTTGAGAGACCGCCAGAATCTCTA GCTGGGCTGATTGGTGAAGATCTTTTTCCATCCAAAACCAGTCTGTAAAGACTGGAAGAG GTGACCGTTTATTCAAATACAAAAATTACAACAAAATATAAGGCACACAAACAGGGAAAA TATGGTCCAATCAGAAGAACAAAATAACTGTCCGTAAACTGACCCAAAAGAAATGGAGAT CTGTGAATTACCTGACAAATAGTTTAAAAGGAACATTTTAAATTAGTGCACTACAAGAAA ACATATACAATGAAACTGTGAATAAAATGAGAATATCAATTAAGAGATGGAAACTGTAAA GATCCAAACAGGAATTCTAAATAACTAAACAGGAATTCTGAAGCTGAAGAATACAGTAAC TGATTTGAAAAAAAAAATTATAGGGGATCAACAGCAGACTTTATTAAGCAAGAGAAAGAA TCAGCAAACTCAAAGACAGGTCATTTGAAATTATTGAGTCAGAGGAACAAAAAGAAAAAG GAAAAATGAAGAAAGCCTAAGGGACTTATGGGGCGCCATCAAGTGAATCAATATATGCAT TACATGAATTTCAGAAGAGGAATATAGAGGAAATGAGGGACAGAATATTTTTCAAACTAC AATAGCCAAAACCTTCCAAATGTGAAAAAGGAAATAGATATCCAAATATAAGAAGCTCAA AGGACTACAGTCATGATGAAACTAAAGAAATTCACACTAAGACACATTCTAGTCAACTTT CCAAAAACAAAAATCTTAAGGGCAACAGGAGAAAGGCAATGTGGTATATACAGAGACTTT CCATAAGAATATCACACATTTCTCAGTGGAAGCATCGCAGGACAGAGTGGAATGAGATTA TATGAGGGATCTTCAAAAAGTTTGTGGACGGTATGTATTATGAAAAAAAAAACTATGCAT GGATTTCAAACTTTTTTTTGGCACTAAAATAAATTCCTGCTGATTTGGGTAAGACATCAA TTTGAAAAGAGTCCCTATCCAGAGCAACATGTATTCTGCTATTACTGAGGCAAGAACAAA TACCAAATTTATGGTGAAGCATGGTGGAAGAATGGTGAAATTATTGATACTTTACAAAAA ATTTATGGGAATAGTACACCAAAGAAATCAGCTGCTTCCAAATGGATAATTCATTTTAAG AAGGGACGAGATGATGATGAAGATGAGGCCCATGGCAGCAGACCATCCACATCAATTTAT GAGAAAAAAATTCATCTTATTCATGCCTAACTGAAGAGGGCCAACAATTCACAGAAGAAG CAATGGCCAAACACCATAGGCATCTCAGTTGGTTTAGCTTACACAATTCTGACTAAAAAA TCAAAGTTGAACAAATTTTCCACTCAATGGGTGCCAAAACTGTTGTGCTAAGATTAGCTG CACACAAGAGCTTTCAGTGAAAAATTCAAACAATTGGCATTGAGATCCTAAAGCATTTCT CGAAAGAATTGTAACAGCAGATGAAACATGGTTTTGCCAGTACAATCCTGAAGACAAAGC ACAATCAAAGCAATGGCTACCAAGAGGGGCACATGGTGAAGAGCAAAAGTCATGGCAATA GTTTTATGAGATATTCAAGGCATTTTGCTTGTTAACTTTCTGGAGGGTCAAAAGAAAATA ACATCTGCCTCCGTCCCAAAAAGAAAAATAAAAAAGAAAATAACATCTGGTTATTATGAG AGTGTTTTGAGAAACCCAAAGCTTTAGAAGAAAAACGTCTGGGAAAGCTTCATCAGCGAG TTGTTCTCTGCCATGGCAGTGCTTCTGCTCGTTCCTCTCATCAAACAAGGACAAATTTTA AATAATTTCCATGGGGAATCATTAGGCATCCACCTTACAATTGTGATTTATTCCTTTTGA CTTCTTTTTGTCTTCTAATTTAAAAACATCTTTAAAGGGTATCCATTTTTCTTCACTTAA TAATGTAAAAAAGACTGCATTGACATGGCTAAGTTCCTAGGACCCCCACTTTTTTAGTGA TGTACTAAATGGTTGATACAATCACTTACAAGAGTACTGGAACTTTTTGGAGCTTATGAC AAGAAATAAAGTTCATATTTTTAATTTTTATCTTTTAATTCAATTTTCCATGAAAGTTTT GATGTCCCCTCATCCATACAGAGTGCTGAAGGAAAAAAAAACCTGACAATCAAGAATAGT ATATATGGCAAGACTTTTAAAAGTGAAGAATAAATAAAGACCTTTCTGGATAAACAAAAG GCGAGGAATTAATTACCATTATGCCTGCCTTATAAGAATTGTTAAAGGGAGTTTTTCAGG TTGAAACAAAGGGATACTAAACAGTAACATGAAAGGATATGGAAATATAAAGCTCTCTGG TGAAATACCCATGGTAGATGCACCAGAAAAAATGAGAAAGAAAGAAAAGCATGTCACTAC AGAAGAATCAATGAAATAGAAAGGCAGCAAGAGCCGCAAAGGGGGACAAAATTACTACTA GCCATACAGAACACAATTAAATGATAATAGTAAGTTCTTACCTATCAGTAATTACTTTAA ATGTAAATTGATTAAATTCCCCAGTCAAAAGACATACAGTGGCTGAATGGATTAAAAAAG AACAAGATCCAACTATATGCTGTCTACAAGACACTTTAGATATAAGGACATACTCGGGCT GAAAGTAAAAGGAGGGAAAAAAGATATTCCATGCAAATGGTAACCCAAAGAGATCAGAGG TGTTCATGTTTATATCAGACAAAAATAGACTTTATAGAAAATAGGTAAAGGAGGGCATTA AGTCTCCCCTTACCCAAGATAGCAGATTGGAGGTATTGCTAGCATGCCTCTCCCACTTAG ACAAAGTAGTGTGTAGAAATTAATGCTCTGAACTTTTTTTTCAAGAAGCAACATAGGAAC TAAACAGAAAAACTGAAAGGAACTACAGACCCTTTGAAAGAAGCAGTGGGCGGCAGCCTA TACTGTGAACCAGACTGAAAACCCCCACAGGAAACACTGAACCTGCTCAACACCAAGCAT ATCACTACTACAACGAGCATCTGAGAAAAACATCACACAAAGATTCTCTATAACCAAGAA ACTTATACAGAGTCTTCACCACTGAAAGCACCTAGAGCCAAAGCTAGGTGACAATAAATT ATAAACATTAAAGTCATACCCTCAAGGGGAATAAAAGAAATAAAAACCCCAGTTAAATGA AAAATAAATTCAAAAATAATGAGAAGAAATAGTCTACCCAAATGAGAAGGAACCAGAAAA ATAATTCTGGCAATATGAAAAAACAGGGTTCTGTAACACCTCCCAAAAAACACACTAACT CTCCAGCAGTGGATTCAAACCAAGATTAAATCTTTGAAACACCAGATAAAAATTCAAAAG GTTGATTATTAATTTACTCAAGGAGATACAAGATAAAGGTAAAAACCAACACAAATTAAA AAAAAATTAGGATATCAATGAAAAATTTTTTTTTAAAGAGATAGATTTTTAAAAGAAAAC CAATCAGAACTTCCAGAAATGAAAGACACACTTAGGGTACTACAAAATGCAGTGGAAAGT GTTAATAATACACTAGATTAAGTAGAAGAAACAATTTCAGAGCTTGAAGACAAGGCTTTC AAATTAACCCAATCAGACAAAAATAAAGAAAAAAGATTTAGAAGAAACAAAGTCTCCAAG AAATATGGGATTATGCAAAACAGACAAAGAATTATAGGTTTTCCTGAGGGAGAGGAAAAA ACAAAAAATTTGGAAAACCTATTTGAGGGAATAATTGAGGAAAACTTCCCTGTCCTTGCT AAAAATTTAGACATCCAAATAAAAGAAGCTCAAAGAAGTCCTGGAAGACTCATTACAAAA AGGACGTCACCAAAGAACATAGTCATCAGATTATCTAAAGTCAATGTGAAGGAAATAATT CTAAGAACAGCGAGACAAAAGCATCAGGTAACCTATTAAGGAAAACCTAGCAGACTAACA GCAGACTTCTCAGCAGAACAAACCAGAAGAGATTGGGGTCATTTTTTAGTCTTCTTAAAC AGAATAACTGTCAGGCAAGAATTTTGTATCCAGCAAAACTAAGTTTCATAAATGAAGGAG AAATAACGTCTTTCTCAGACAAGCAAATGCTGAGGGAATTTGTCAATACTAGACCAATGT TACAAGAAATGCTAAAAGGAGTTCTAAATCTTGAAAGAAAAGATTGATACACACCAGGAT AGAAACCTCTGAAAACATAAAATTCACACGGCTTATAAAACAATAACACAGTGAAGAAAA GAAAGTATCTAGGTAACAATCAACATTATGACTGGAATAGTATCTCACAATACTAACATT GAATGGAGATGGTCTAAGTGCTCCATTAAAAGATACAGATTGGCAAAATGAATAAAATCG TCACAAACCAAATATCTGCTGTCTTCAGGAGACACATCTAACACAAGGATTCTTATAGAC CCAAGGGAAAAGGGTGGAAAAAGATATTTCATGCAATCAGAAACCAAAAGCAAGCAGGAG GAACTATTCTTATATCAGATAAAACAGACATTAAGGCAACAATAGTAAAAAAAAAAAAGA CAAGGTCATTATACAATGATAAAAGGATCCAATTCATGAAGAAGATAAAATAATTCTAAA TATATATGCACCTAACTCCAGAGCTCCCAGATTCGTAAAGCAACTACCACTAGACCTAAG AACAGAGATAGACAGAAACACAATAATAGTAGAGGGCTTTCACTCCACTGGCAGCACTAG ACAGAGCACTGAGGCAGAAAGTCAACAAAGAAATACTGGACTCTAGAACAAACTGACCTA AGAGATATTTACAGAACATTCTACTCAAGAACTACCCAAGAACTGCAGAATATACATTCT TCTTATCAGCACATGGAACATTCTCCAAAATAGATCATATGTAAGCTGCAAAACAAATCT CAATAAATTTTTTAAAAATTGAAATCACATCAACCATATTCTCAGACCACAGCAGAATAA AATCAATTCCAAGAGTAATCCTCAAAACTGTATAAATACATGGAAGTTAATCTGTTCCTG AGTGATTTTTGGGTTAACAATGAAATCAAGATGAAAATTGAAAAATTTCTGAAATGATTG ATAACAATGACACAAGTTCTCAGAACCTCTAGGACACAGCAAAAGCAGTGTTAAGAGGCG TTTATAGCACTAAATACCTACATCAAAAAATCTGCAAGGTTACAAATTGACAAGCTAATG TCATGCCTCAGGGAACTAGAAAAAGAACAAACCAAACTCAAAGCTAGCAGAAGAAAAATA ACAAAGATCAGGGCAGAATGAAATGAAATTGAAAAGACAGTACAAAAATCAATGAAACAA AAGCTAGTTATTTGGAAAGATAAACAAAACTGATACACTACTAGCTAGATTAACCAAGAA AAGAAGAGAAAAGATTCAGATAAGCTCAATTAGAAGTGAAAATGGAGACATTACAACTGA CACCTCAGAAATATAAAAGACTATTTGAGATTACTATGAGCACCTCTATGCACACAAGCT AGAAAATCTAGCGGAAATGGATAAATTCCCGGAAACATACGACACCCTAGCTTGAGTCAG GAAGAAATAGAAATCCTAAACAGACCAATAACAGGCTGTCAGATTGAATCAGGTAAACAA ACAAACAAACCAAAAAAACAAACCTGTCAACAAAAAAAGCCCAGGGCATATGGATTCAAG CCGAATTCTACTAGACATTAAAAGCAGAACTGGAATCAATTCTACTGAACTATTCCACAA GATTGAGAAGGAGGGAAACCTCCCTACCTCATTCGACCCAGTCAGTATCATCCTGATACC AAAGCCAAGAAAGAACCTAGCAAAATAAGAAAACTACAGACCAATATCCCTGTTGTATAT AGATGCAAAAATCCTCAACAAAATACTAGAAATGGAATGAACTAGAACAAAAAAAAAAAT CATGATGAAGTGGGTTTTATTCCGACTTTTTCTTTCTCAATAGGTGCAGAAAAAGCATTT GATAAAATCTGGTATCCCTTTATGATAAAAATTCTCAACAAACTAGTTATAGATGAAACA TACCTCAAAATAATAAAAGCCATCTATGACAGATTCACAGCTAACATAATACTGAAAGGG GAGAACTTGAAAGAATTCCCCCTAAGAATGGGAACAAGACAAGGATGCCCACTTTCACCA CTTCTATTCAGTATAATACCGGAAGTCCTAGCCAGAGCAATCAGGCAAGAGAAATAAAGG GCATCCAAACTGGAAAAGAGGAAGTCAAACTTATGTCTATTTGCTGATGATGTGATCATA TACCTAGAAAACCCTGACTCCTCCAAAGAATCCTAGATCTGATAAATGAATCCAGTAAAG TCTCAGGTTACAAAATTAATATACATAAATCAGTAGCAATGCTATATGCACTGAGAACCA AGCTGAGTATGAAATTGAGAACTCAATTCCTTTTACAATAGTTATACAAAAATATTTAGG AATATATATAACCAAGGAAGTGAAACATCTGTACAAGGAGAACTACAAAATACTGCTAAA TAAATCACAGGTGACACAAACAAATGGAAATACACCTTATGCTCATGGATTGGAAGAATC AATATCGTGAAAATGACCATACTGCCCAAAGCAATTTACAGATTCAATGTAATTCCTATC AAAATAACCAACATCGTTTTTTCAGATAATTAGAAAAAAAATCATAAAATTCACATGGAA CCAAAATAGAGCCCAAATAGCCAAAGCAATCCTAAGCAAAAAGAACAAATCTGAAGGTGA CATCACATTACCTAACTTCAAAATACACTACAGGGCTATAGTTACCAAAACAGTATGGTA CTGGTAAAAAAGTAGTTACATAGACCGTGGAACAAAATAGAGAACCAAGAAATAAAGCCG AATACTTACAACCAACTGATCTTTGGCAAAGCGTACAAAAACATAAATTGGGGAAAGGAC ATCCCATTAAATAAATGGTGATGGGAAAATTGAATAGCCACATGTAGAAGAATGAAACTG GATTCCTACCTGTCACCATATACAAAAATTAAGATAGATTAAAGACTTAAATCTAAGACC TGAAACCATGAAAATTCTAGAAGAAAAACTTTTCTGGACATTGGCCTAAGCAAAGAATTT ATGAATAAGACATCAAAAGCAAATGCAGCAAAAGCAAAAATAAATAAATGGGACCTAATT AAACAAAAGCTTCTGCACAGCAAAAGAAATAACCATTAAATAGACAACCTACAGAATGAG AGAAAAAATCTGCGAATTTTGCATCTGACAACATACACGGAACTCAAATCACTAAGAAAA AACAAATAATCCCATTAAAGAGTGGGCAAAGGACATGAATAGACAGTTTTCAAAGGATGA TTTGCAAATGGCCAACAAACATGCAGAAATGCTCAACATCACTAATCATCAGGGAAATGC AAGTTAAAACGCAACAAGATACTACTGTACCCCAGCCAGAATGACCATTATTAAAAATTC AAATAACAATAGATGTTGGCATGGACAGGGTGAAAAAGGAACACTTATACACTGCTGGTT GGAAAGTAAATTAGTATAACTTCTATAGAATACAGTATGGAGATTTGATCCATGAATTCC ACTACTGAGTATCTACCCAATGGAAAGGAAATCAATATATAAAAAAGACATATTTATCAC AGCACAGTTCACAATTGTAATGATACGGAATCAACCTAAATACCCATCAACCAAAGAGTA GATAAAGAAAATGTGGCATATGTATATTGTAGAATACTACTCAGCCATAAAAAAGAATGA AATAATGTCTTTTGCAGCAACTGGGATGGAACTGGAGGCTATTATTCTAAGTGAAGTAAT TCTGGAATCAAAATCTAAATCCAACATGTTCTCATTTACAGGTGGTTTCTAAGCTTATGG ATATGCAAGGGCATACAGAGTGGTATAATGTACATTGGAGACTCAGAAGGCTGGCAAGCA GGAGAGAGGTGAGAGATGAAAAAGTACCTATTGGATATAGTGTTCAGGTGGTGGGTGCAC TAAAATTCTAGACTTCTCCATGGTACCGTTCATCCATGTAACCAAAAAATCACTCATACC CCTAAAGCTACTGAAATAAAAAAAAATTTTTGAAGTACATTATGTAATGATGAAAGGGCC AATTCACCAGGAAGGTATGACAATGATAAATGTACATGTACTTTACAGCAGAACACAAAA AATATATAAGGCAAACATGGACAAAATTGAAGGGAGAAATAGTAACATAATAATAATAGA ATATTTCAGTGCCCCACTTTTAATAACCAGACAGAATATTAGTAGAGAAACAGAGCACTT GAATAATGCTATAGACCAATTGGACCTAACAGATACATACAGAACACTGCACACCAAAAC AGCAGAATAGATAGTCTTTTCAAGTGCACTAGGAGCATTCTTCAGGATATATCACATGGT AGGCCACAAAACTAGTATTAAGAGAAGATTGAAGTCATATCAAGTATCTTTTTAGACCAT ATTGTAATAAAACTAGAAATCAGTAGCACAAGAAAAACTAGAAAATTCACAAATATGTGG AAATTAAACAACACACTCTTGAATAATCAGTGGATCAAAGATGAAATCATGGGAAATTAG AAAATATATTGAAAAATGAATATGAAAACACAACATAGCACAACACATAAGATGCAGCAA AAGCAGTAGTAAGAGGGAAGTTTATAGCAGTAAACATCCATATTAAGAAAATCTCCAATC AACAACCTAACTTTATACTTAAGGGGACTAGAAAAGGAAGAACAAGCTAAACCCAAAGTT AGCAGAAGGAAGGGAGGAATAAAAATTAGAGTCCAAATAAATGAAATAGATAATAGAAAA AGAGTAAAAAAAAAAGGCTATGAAACTAAGAGTTGGTTTCTTAAAAAGATCAACAAAATC AACAGTTCCATATTTAGCTAGAATAAGAAGAAAACAAAGACTCAAATAACAAAAATCAGA AAAGAAAGAAGAGACATTACAACTGATGCCACAGAAATGTAAAGTATCATAATAGAGTAC TATGAACAATTATACACCAACAAATTATATAACCTTGAAGAAATGCATACATTTCCAGAA ATGTACAATCAAGACCAAATTATGAAGAAATAAAATATCTGAGTGGACATATACTGGTAA GGAGATTGAATCAGCAATCAGAAGCCTCCTGACAAAAGCCCAGGACCAGATGGCTTCACT GGAGAATGCTTCTAAACAATTAAATAAGAATTAACACCAGTCCTTCTCAAACTCTTCCAG AAAACTGTAGAGGAGGAAACGCTTGCAAACTCATTCTACAAGGTCAACATTACTCTGATA CCAAAACCAGGATATGCAAAAATCCTCAACAAAATTTTAGCAAACTGAATTCAACACCAC ATTGAAAGAGTGGTGCATTATGACCAAGTGGGATTTATTACTGAAATGCAAGTATGGTCC AGCATATAAAAATCAAGGTAATACTGATATGTTAACAGAATGAAGGAAATGTAACACATG ATCATCTCAATTGATGCAGAAGAAGCATTTGAGAAAGTCATACACCCTTTCATGACAAAA CACTAACCAAACAAGGAATAGAAGGAAATTACCTCAATGAAATAAAGGGCCATGTGTGAA AAGCCCACAACTGACATCATACTCAGTGGTGAAAACTGAATCCTTTCTCTTTAAGATGAT GCACAAGGGAAGGATTCCTTTTCTCACCACTTCTATTCAACATTGTATTAAAAATTTTAC CCAGACCAAGCAGGCAAGAAAAACAAAAAGCATCCAAATAGGAAAGGAATAAATATAATG ATCTTTTCATAGGTGACATGATCTTGTACGTAGAAAACCCTAATGATTCCACACACACAC ATAAAACTGCTAGAACTAATAAACAAATTTAGCAAAGTTGCAGGACACAAAATCAACACA CAAAAGTCAGTTACATTTCTATACTCAGCAATGACCAATCTGAAAAGGCAGTTGAGGAAA CAATCACATTTACAGTAGCATCAAAAAGAATAAAATACTTAGGAATAAACTTTACCAATG AGGCGAAACACTTCTACACTGAAAACTACAAAACATTGCAGAAAAAATTGCAGAAAACAC AACTAAATGGAAAGACCTTCTGTGTTCATGGTTTGGAATCCTTAATATTTTGTTAAAGTA TCTCTATTACCCAAACCAATCTACAGATTCAATATAAGCCCTATTGAAATAGCAGTGTTA TTTTTTGCAGAAATAGAAAAAAAAATTCTAAAATTCATATGGAATCTCAGAGGACCCAGA AAAGCCAAAAAAGTCTTGAGAAAAGAAAAACAAAGCTCGAAACCTCGTATGTCCTGACTT AAAAACATATTACAAATCCATAGCAATCAAAATATTATGGTAGTGGAATAAAGACAGACA GACATATAAGCCCAGTGTGGTGGCTCACACCTGTAATCGCAGCACTTTGGAAGGCAGAGG TGGGCAGATCGTTTGAGATCAGGAGTTTGAGACCAGCCTGGGCAACATGGCAAAACCCTG TTTCTACAAAAAATAACAAAAGTTATCCAGGTGTAGTGATGTGTGCCTTTGGTCCTAGCT AATCTGGAGGCTAAGGTGGGAGAATTGCTTGAGTCCGGGAAGTTGAGGCAGCAGAGAGCT GTGATCACGCCACTGCACTCCAGCCCAGGTGACAGAGCAAGACCCTGTCTCAAAAAAAAA AAAAAAACAAAAAAAAAAACCCAGACATACAGACTAGTGGAACAGAATAGAGAATCGAGA AATAAATCCTCGCCTATATAGTCAAATGATTTTTGACAAAGATGCCAAGGCTACTAGTAG GGAAAGGACAATCTCTTCAACAGATGATGTTGGAAAAACTGGATATTGGCATGCAGAAGA ATGGTATAACCTTATACCAGATTAAAAAAAATTAAATGGATTAAGACCTAAATGTAATAC CTGAAATTATTAAGCTCCTAGAAGAAAACAGGGGAAAAGCTTCATGACATTGGGTTTGGC AATGATTTTGTGGATTTAACACAAAAAGCACAGGCACCAGAAGCAAAAATAGACAAATAG GACATCAGACCTAAAAACTTTTGTGCAGCAAAGGAAAATCAACAGAGTGAAAAGGCAGTC TACGTAATGGGAGAAAATAATTGCAAACCATATATCTCATAACGGGTACATAACCAATAT ATGTAAAGAACTTCTGTAACTCAATAACAAACATCAAAATTTAAAAATGGGCAAAGGACT CGAATATATCAAAGAAGATATACAGTTAGCCAACAAACATGAAAATATAAACATCGGCAT GAAAAGATCAACATCAAGTAATTGTTAAGGAAATGTAACTCAAAACCACAAGAGGTATCA CCTTGCACTCATTAGGATGGCCATTATTAAAAAAAAACAAACTGAAAAAAACAAGTGTTG GTTAGGATCTGGAGAAATTGCAATCCTTTTGCACTGTTGGTGGGAATGTAAAGTGATGCC ACTAGGGAAAATGATATAGAGGCTCCTCAAAAAATTAAAACCAAAATTACCGTATAATTC AGCAATCTCACTTCTGGGTTTATATACAAGGAATTGAAAACAGGACCCCATGGAGATATG TGCACACCCATTTGCATTGCAGCATTATTTCCAGTAGCTAAGAGGTGGAAACAACCTAAA TGTTAATCAGCAGAGACAGGGATAAAAAAATGTGATATAGACATACAATGGAATATTGCT CAGGATTAAAAAAAGGAAATCCTGTCATATGCTACAACATAGATAAACCTGGAGGTCATC ATGCTAACTTAAATAAACCAGTCACAGACACATACCACATGATTCCACTTACATGAGGTA TCTAAAATAGCCATACTCTTAGAAACAGAAAGTAGAATGGGTAGTTACCAAGGGATAGGG ATGAAGAAAGGGAGAGTTGTTTAGTGGTTATAGAGTTTTGGTTTTGCAAGATAAGGAAGT TCTGTGTTTCTTTTTTACAACAATGTGCATGTAGTCAACACTATTGTAATGTACACTGAA AAATGGTTAAAATGGTAAATTTTGTTACTCCTCCCATCCCACTTTTTTAGACAGGGTCTG GCTCCTGTCACCTAGGCTAGAGTGCAGTGGTGTGATCATAGCTCACTGCAACCTTGAACT CCTGGGCTCAAGCAGTACTCCTGCCTAAGCCTCCCCAATAGCTAGGACTATGGTTATGTG CCACTAGGCTCAGCTAATTTTTTTAGGTTTTGTAGAGACAGTCTTGCCATGTTGCCCAGG CTAGTGTTGAACTTCTGGCCTCAAGCGATCCTCCTGTCTCGGCCTCTCAAAGCACTGGGA TTACAGGGTGTGAACCACTATGCCTGGCCTATGTTTTTTTTTTTAACCATAATTAAAAAA AAAAAAAAAAGAAACCACCTGTCTGCATTCTGATATTTTACCTGATAGGACAAATTTGCC TTAGGTAAACCTTTATAAACAGGCATGATCTTTTAGAAACTACTCAAACGTTTTAAAAGG AAGAGCAAGAGCAAGTGTCAGTTATGACACTTGAAGAGTCATAACTGGTTACCTTTGTTA CAGTTTAAAAAAGGTAGCACTTTCTGTGTTTCACAGGGTGAATGCCTTCATCCATTGGAA CCTGAACCATGAGTATTTCCTTCTGAGACTTTCATCAAACTAAGTCTGCATGAAGCCTGA GTCCTGTGGTAACTGGAACCTCATAATAGCATTTACATTTGGTGTTAAAATGCACCCAAC AGGAAAAAGGATTCAGTTATTTTCAAGCTTCCAAATTCCAAATGTGCTGAATAGACATTT CCTTTAAAAAATAAATATACAAAATGGATTTGTGTGACTTGAAGTTTAAAAGAAATGTTC TTGCATGCCATAGTTAAGAATTGTAACAATATCACATTCTCAAGTTTACTTATTTTAAAA GTAGACTGTCATGGTTTGGCTCAGCTACTAAATTAAATTATTGCTGGCTTGAACATTCCT GTTGGTTACACTGTAATCTTTACCTCCCTTGGAAAATATGTCCGATTTTGAGTGTTTATT TCAGACTTGGCTTGAAACACCTCTGTTTAGCAGTGAAGTATGGATATATATGTGTGATCT GTGTTACGTATGTAGAAAGGAAAGAAATAGAAAAAAGTTTTACATTGTGTGTTACAAATA CACACTAACAGGAATACATATATACATACATATATGCAACTAGAACCATGCTTATCAAGG ATCAAGATAATATAACTATACTGAATTAATAGACATGCATACATACATACATGTGTATCC ATTAACATGTTATTACAGGTTGAATTGTGTCTCCCTTTCCCCCAAAATCAGATGTTGACA TTTTCACCTCTGGGAGCTCATTTGGAGATAGGGCTTTTGCGGCGGTAATCAAGTTAAAGC AAGATCATTAGGTTGGGTTCTAATCTAATATGACTGGTATTCTTATTAACAAGGGGAACT TTGGATACAGAGATATGCATAGAAGGAAGACAGTGTGAAGAGACACAGAGAAAAGACAGC TATCTACAAGCCAATGAGAGAGACATGGAACTCATCTTTCTCTCATACCCCTCAAAAGGA ACCAACCCTGTCAACACCTTGCTTTTGTATTTACTGCTTCCAGAAATTGTGAGACAATAA ATTTATATTGTTTAAGCCACCTAGTTGGTGGTACTTCATTACAGCAGCACTAGCAACTAA TACAAGGTATTTCTCTATTATGCTAAGAATTCAGGATATACTCATTTAGATAGGATACAC GATTAGTCTTTACATGTTTTAACTTTTCATAGTATCTCCTAAGCACTCTAAGAAACTAGT TTCCCTAAAAATAAAGAAAAAAGGAAAAAAAGAAATTAGTTTCTCAAGTTTGCAAAATTA AGAAATTAGTTTCTCAGTTTTGCAAATTGAGAAATTAACGTTGACTGTGATGATGAAGCA GTTAGATTTGGAAAGTGGATCCTACTTTACATAAATAATAATCAGACTTTTTCTTTTATT CAGGAGTCTGTGAGTTTGTGTAATTTGTAGTGATAGTATCAGAGTTTACCAGAGGCCTAA TGGATTGGAAAGTCAGAATCAGAACAAGCAAATCTACCCTCATCCAGCACCAGAATTAAA AGTTCTCAAAATTGCGCACATGGGAATTAAATTTCTCCACATTAGAAACAGATGCCTTCA AATAACTGATTTTTCCATTGCCCCAACGTGTAAGTGCCTTTTTATTGTGCTCATTTTGTC ATCAGTAGAAGGACGCTTGAGTTCAGTACTTGGAAGAGTGGAAGGGTGCAGTATTCCTTG GGCCCTGTCCCTTTACGTTTCATGGTATGCCAGGGATGTCTGTGTTTACTACCTCCAACC AATGCAAGAACATACCTGAACAACCCAAACTCCTGACTGGGGCTAATTGGAGTTAGTGAC AGAGAAGAACACTATTTTACAGTGTTGGGTATTTTTGTTGTTGCTCTGGAGGTTGGGAGG GATTAGTCTTTGTCAGGAGATAGGATTTAGCAGAATATATCTATTTATATCTTGTTTTAT CTATTACATCTCCATCCTATTGACTTCTTTCCTGAACCGGAATTAAGCAATGAATGCTGT TTGGGCATTTTTAGTGTGGCTGTTCATTATTACCTGGATAATTCAGAGTACTTCTAGGTC ATGACATAAAAATGCTGTTATTTGTATTAGCTTACAGATACTGTTGGTCTGTCTCCAATG TTGTTGTTTTTCAAATTCCAGGAGTAACAGGATGGAAGGTTGCAGAGCTCTAAGTAATAA GTAAAGTGGCCTGGGATACTGAACATAGGGAGTGGTGGAGATTGAGGCAAACTAGACAGA TAGCTATGCCTTGTTTAAAGGGGCTGCCTGTGTTGTATTACATCTGGTTGTTGTCCTGTG AAAATGCAGGCCAGATGTGGCCAAATCTTCCTGTTTTTCAAACCAAGTGGTAGAAATTTG AATTTTTACAAGCAGTCTCCCAATTTTTATTGTGACAACTAGTTCAGATTACGAAAAATA TTTATGGGCCAAGTAAAATACCACCTGTTTTCAGCCTCTAGTGTAGGATATATGAAGCCA GCTTGTTCTTCAGGTAGCAGGTGGTGCTTACAGGTCATCTCTACTGAGGCATCGTTGGTG AAGTCCTCTAAGACTCAGCTCTGGGATCCTCTGTAGTGAATGGCTCTCATAGTTGCAGGA AAAACCCAGGTCCAAATGACACCCACAGTTGACCACAGTTTTACCTAATTAAGTAAAAAA CTTTTTTTAAAAAAATAATTTATTTTGTTATCCTGTTACCAGTACTTTCAAATACTTAAG AAAAAAATCAATATTAAAGTATCAGTTTTGCAATCCAGAGGATATTTGTACTTTTTCAAA AAAATTTAAAAATTAGAAAAAAGATAACATATTGGCCTCCTGCCTTTTAAATATTTAAGG GATGAATCAGACTTTCAGATGTGCTTAAATTGGTACCTAGAGACCTAATGGAGGTTTCTT ATTTTCTTCACTGGTAAGATTTTGTCATTCATTCCAGTAGATACTTTTAAGCAACCTTTT TATTTTAGAGCAGCTTTAGAGATAAAGTTATGAATATAGTACAGCGAGTCCCCCTATACG CCAAACCCAGTTTCCCCTTATTATTACCATCTTATATTAATTAATGAGCCAGTAATGATG CATTGTTATGAACTACAGTCCATACTTTATTCAGATTTCCTTAGTGTTTACCTGCTGTTC TTTTTCTATTCTGGGACTCTATCCAGAATATCACATTGCATTCATTGTCATGTCTCCCTT GGCTCCTCTTGGCTGTGACAGTTTCTCAGACTCCTCTTGCTTTTGATGATTTTGACAGTT TTGAGAAGTATTCCATAAAACATCCCTTAGTTGGGATCTGTCTGATGTTTTTTTCTCATG ATTATGTATTTTTGGGGAGGAAGTCTAAAGAGGTAAAGTACCATTCTCCTCATATTAAGG GTGTACACTATTGTGTCAGCATCATGTTTTACTGTTGATGTGAATCTTGATCACCTGGCT GAGGTGGTAGTCATCAGGTTCCTCCATTGTAATGGTATTGAAGGCACTGCGTGCAGCCCA TGTGTGAGTAGGAGTCATGCTGCACTTCTGTGAGAGGAGAGTATCTACATCAACTATTCG GAATTCTTCTGCATAAGAGATTGGTCTCTTCTCTGTGTATACATGCATGCATGTATGTAT GTCAGTATGGATATTTATTTATTTTATACTTTGGATTATAATCTAATACTTGTTTATTTC ATTGATCAGACTGTTGTAGCTTTGGCCATGGAAGCTCTTTCAGTTGGCTACTGTGTCCCT TTGATATACCCCCACTGTTGCATTGTTGTTGTTTTTGAGTACTTTCTTAATTTCTGGCAC TACAAGATGCTCATGCACATCTTGTATATTCCCTGCTCCAGTGCTAGAATCAATGATTTT TTCCAAGGAGCCCTGGTTTCTTTTATTGGAGACTGTTACTAGAAACCAAGATCTGCTATG CTCATTGCTACTGGGATGTGTTGCTTCTAGGCTCTTTCAGCTGACAGAGCAAGGAAATAT GTTGTGTATAATAATCTGTGTATGTTCACATATTTATAAATATTTGTATTTGTGTCTGTC TATATTAAGCCAAATATGTGTTTATACTGATGACTTCAACTCTTAATCTGTTACCACATG GCTCATTGGAGTTTTCTCTCATTGCTTCTCTGTAAACTGTCATTCAAACACTGAGAGATC TGGCTCCCAAGAGCCACGATCCATTTGCATTGTTCAACTCCAGTATACAGTATAATAGTG ATTTTAGAATTCCTAACTAAATACCCTGTGAGAAACAGTTTTATCCACAGAGCTTATGCA CAGTGCCTTTTGCCTTTAGTCTTACCTACTCCACTTATTTGTAAGGATGCTCAGGTCAGC ATCTTTCCCATTCCATCACTGAGTGTATTTTATACATTTGCTAGATTCTTTCACCACAGC CTGCATTCCATCTTGGATTCTCCAACCTCCCAAATGATTTTTTACAATTTGCATACATTA AGGTTAGCTCTGTATTTTGTGGGTTTTGAAATTTACAATGTCATGTATCCCCCATTAGAA TATCAAAGAGAATACTTTCATATCCTAAAAATCCAATGTGCTATATTTATTCAACCCTCA CCCCTTCCGAAACCCCTGGCAATGATTGACCTATTTACTGTCACTGTAGTTTTGCCTTTT TCAGAATGTCACACAAATGTCATATAGTACATAATCTTTTCCTTGGCTCAACATCATATT TATGTATATGCATATAAGAGTTATCTATGTTGTTGTGTTTTTGGGGAGGGGAGGGGACAG GGTCGTGCTCTGTCACATAGGCCCTTGTTTTTGTTTTAGTTTACTTTGGGGTGTGTGTGT GTCAGGGTTTCCCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCATGGCTCACTGCA GCCTCAACTTCCTGGGCTCAGGTGATTTTTCCACCTCAGCCTCCTGAGTAGCTGGGACCA CACACCTGGCCAACGTTTATATTTTTTGTGGAGACAGGGTTTTGCCATGTTGCTCAGGCT GGTCTCAAACTCCTAGACTCAAGCAATCTGCCCATCTTGGCCTCCCAAAGTGCTGGGACT ACAGGCATGAGCCACCTCCCTCAGCCAGTTTTTTTTTTTCTCCTATGAATAGTATTCTAT TATATGGATGACAACAGTTCGTTTATACACTCACCTGTTGAGATTGTTTCCAGCTCTTGA CCAGTATAAATAAGACTTCTATAAACATTCTCATGCAGGTGTTTATGTTGACATAAAATT TCAAAGGAGCACAATTGCTATATTATATGATAGAGACTGTGTTTAGCTTTTTAAGACACT GCCAAACTGTATTCCAAAATTTGGAATGGTATACAGCTTTTGCATTCACTCCAACAATGA ATTGAGAGCTCCTGTTTCTCTGCATCCTAGTCAACGTTTGGTATTGTCAGTTTTTAAAAT TTTCGCCATTTTAATAGATGTCTAGTAGTATCTCATCATTTTAATTTGTATTTCCCTAAT GAGATAATGATGTTGAGCATCTTTTCGTATGCTTATTTGTCATCTATGTATCTTCTTTGG TGAGGAGTCTGTTCAGATTTTTTTTTTTTGGCCCTTTTTTTTGTTGTTGTTATTGTTGAG TTTCAAGAATTGTTTGTTTGTTTGTTTTTTTCTTTTTTTTTTTTGAGATGAAGTCTCACT CTGTTGTCCAGGCTGGAGTGCAATGGTGTGATCTCGGCTCACTGCAACCTCCGCTTCCTG AGTTCAAGCGATTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGATTACAGATGTGCACCAT TGTGCCCGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGTTTTTACCATGTTGCCCAGA CTGGTCTTGAACACCTTTACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGG ATTACAAGTGTGAGCCACTGTGCCCAGCTTAGTTTCAAGAATTCTTTGTATATTTTAATT ATTTATTTAGTTTGGAGACAGGGTCTTGCTCTATCACCTTGACTGGGGTGCAGTAGCATG ATCATGGCTCAAAGCAGCCTCAAAATCCTGGGCTCAAGTAATCCTCCACCTCAGCCTTCT GAGTAGCTGGGACTACAGGCAGTGCCACCATACTCTACTAATATTTTATTTTCAAATATT TTTGTAGAGACGGGGTTTTGCTATGTTGACCAGGCTGGTCTCAAACTTCTGACCTCAAGC AGTCCTCCCACCTCAGTCTCCTAAAGTGCTAGGGCTACAGGCATGAGTCTCCCTGCCCCG CTGTATATTTTATATACAACTTCTTTATCAGACATGTTTTCTAAATATTTTCTCCGAATC TTTGGTTTGTCATTTCATTCTCTTAATAGTGTCTTTCACAGAGTAGAGTTTGAATTTTAT TAAGTCCAATTTATCTATCTTCTTTCATAAATAATGTTTTTTTGTATTGTATCTAAAAAC TCATCACTAAACCCAAGGTCATGTAGATTTTCTCCTATGTGTTCATCTAGAAATTTTACT GTTTTGCATTTTATGTCTAGGTTTATGATTCATTTTGCATTGTTTGTAAAATATAAGGTC CAAGTCCAGGTTCATTTAATTTTTTTCTTGGTGTATGAATATACAATTATTCTAGCATCA TTTGTTGAAAAGACTATGCTTTTTTCATTGAATCGCCTTTCTGTGTTTTTCATAAATCAG TTGACTACATTGTATGGGTTGATTTCTGGGGTCTGTGTCTTGTTCCATTGACCAATGCAT CTATTCTTTCTGCCAATTCTACAGTTTGGATGGAGTTTGATTTTAATTGGTATTAATTTT TATTTGGGGTTTGAGAAAGAGGTTCTCATTCAATTTTATGACAGTGCTTGTGTGTTTGGG TGTTTTTAAGATATTAGACATTTTATCTCCTTCATCTTGTCATCAGCTTTTAACATTCCA CATCCTGTTTGTTTTTAAGTGACATTGAGAATGCACGTCTCTGATCTTCCTTCACATCTC AGTACTAGTAAATACAACCTCTTTCTGACATATGATATACTTGTTTCCTTTTTATCTGTT CCCCTGATCCTTCACTATTTCATAAAAGTTCATAAAAGCAGGGCTTTTAAAATTTGTTGT TCACTGCTGTATCCCCTTTACCTAGGACTTGCCTGGCATCTGGTAAGATCTCAATGAAGT AATGTGAACTAGATTAATGAAATATGAGGTCTCACATTTATAACATCTTTGAACAAGAGG TTATTATACAAAGGTGAATTTGCTAAATGGCTGAACTTTATACCTTTAAGCTGCAAAACT TTTATTATTTATTTACTTTTAAATTGACATAAAAATTTAATATGTTCATGGTATATACAA CATGATGTTTTGATATATGTACATATTGTGGAATAGCTCAAATGAGCTAATTAACATATC CATTACCTTACATACTTAATTTTTGTGTGTGTGGTGAACACATTTAAAATCTGTTTTCTT CTCAGTAGTTTTCAAGTATACAGTACATTGTTATTAACTGTAGTCACAATGTGTACAGAT CTCTTGAACTTACTTTTCTTGTCTGTGTGAAATTTTGTATCCTTTGACCAACATCTTCCT AATTCCACACCTCTCCTTCCCACCCAGCCCCTGGTAACCATCATTCTACTATTTGTTTCT GTGAGTTTGACTTTTTTAGATTTCGCATATAAGTGAGATCATACATAATTTCTCTTTCTC TGACCTTAGGACTTTTATGACTTCTGACCTCTAAAACTGTAAGACAATAAATTTGTGCTG TTTTAAGTTGCTAAGTTTGTATTATTTTGTTACAGCAGCATTAGGAAAGTAATACAGATG TTTAGTGCAAGGAACACCATGCAAGTTAATTTTAGAAATTAGTCTTCTGAAATGTTTATA AAATATATAAAGACAAGTTTTTTTTGGGGGGGGATAGACTCTCCCTTCTTTTTTTAGCTT TTTCTTTAATGAACATCAAGCAGATTTTAATGCTCATTTTGTGTGCTAACACTTCTTTGT CATTTTCAAGGGTAGCTTTTTGGAACTTTGTCAATAGAGTACAAAAATGTAAAAAAAACC AGTCTACTGGGTCTGGATGGGAAAGAGTTCACTCTTCATGTGTTAAGAGTCTTAACTTCT TGGTTACCTACAGTGTTTGAGGGGAATGGTGACTTATAGAACTAAAAACATTGAATAACT TATGTTTTACTATACAGATTTATAGTTGCACAAATCTGTAGTTGATATTTTCAAACTGTA ATTACATTTTATTCTTATTTCTTTTTTTATTATTTTATTTATTTATTTATTTTTGAGATG GAGTCTTGCACTGTCACGCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAAGCT CCGCCTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGG TGCCCGCCACCACACCCAGCTAATTTTTTGTATTTTTAGAAGAGATGGGGTTTCACCGTG TTAGCCAGGATGGTCTCCATCTCCTGACCTTGTGATCCACCCGCCTCGGCGTCCCAAAGT TCTGGGATTACAGGTTATTCTTATTTCTTAAACACACCGTAGTGAACTTTTTTGTTTGTG CTATGTCATATAGTATTTTGACCAGAAATAAGGAAATTGAGTTAAAGTCCTGTTTCTGAA ACTATCTAGCCAAGTGATCTTAGGAAAGTTATAATTTCTCTAGGTCTCAGTTGAACACTA GATTGGTGGTGAGATATCTTCAGATCTCAACAGTCTCTAAAATTCTGATTGATATTGACT GTATTCCTTGTGACGTTTTTTAAACAGGGCTTTCCTCACAATGATATTAAAGTATGTAGA ACATTCCACGTAGGCATGGGCTTTCAGACAGATATATAATATTTTAGTTATTATTTTAAA GAAATTTTTATTCATCTGCCTTTGTTGCTAAGTGTTCCTGTGTTTATATATTTTTTCCTA CTGAATTGTAGTTTTGTTCTTTTGTCTTTCCCTTTAAATTGACCCCCATAGGGCTTGTTC ATCCCTATAATCTGTTAATAGACTCTCTCAATAAATGTATGACAGATGTAGTGGTGGAGA GAAGACAGACCTCCCAAAGATGTCCATATTCAAATCCCTGGAACTTGTGACTGTGTTACC ATGGCAAGGGGAATTAGGTTGCAGATGGCTTTAAGGTTACCAATCAGCTGTCCTTAAAGA GGTTAGCCTGGGTTATCCAGGTGGGCCTAATGCAATCACATTGGCAGTAAGTGAAAGAGG GAGGCAAAGGAGTTAGAGTCAGAGGAATTCAATGTGAGAGCAACTTGATTGGAATTGTTG GACTTCAAGATGGAAGGAAGCTGCAAGGAATGTCGGCAGCCTCTAGAAGCTCCAAAAGTC AAGGAGACAGATTATCCTCTAGAGTTTCCAGTAGGATTGCAGTCCATCAACACCTGGATT TTAACCCAGTGAAATCCATTTTGGACTTCTGACCTCTGAAACTGTAAGACAATAAATTTG TGCTGTTTTAAGTTGCTAAGTTTGTATTATTTTGTTACAGCAGCATTAGGAAAGTAATAC AGATGTTTAGTGCAAGGAACACCATGCAAGTTAATTTTAGAAATTAGTCTTCTGAAATGT TTATAAAATATATAAAGACAAGTTTTTTTTTCGGGGGGGCTAGACTCCCCCTTCTTTTTT TAGCTTTTTCTTTAATGAACATCAAGCAGATTTTAATGCTCATTTTGTGTGCTAACACTT CTTTGTCATTTTCAAGGGTAGCTTTTTGGAACTTTGTCAATAGAGTACAAAAATGTAAAA AAAACCAGTCTACTGGGTCTGGATGGGAAAGAGTTCACTCTTCATGTGTTAAGAGTCTTA ACTTCTTGGTTACCTACAGTGTTTGAGGGGAATGGTGACTTATAGAACTAAAAACATTGA ATAACTTATGTTTCAATTTATACTATTTGGATTCTGTAGAAGAAGAATTTTATTTAAAAT AATGTTTTTGTTATGTTTATTTTAAATGATATTGAAAATGAATTACATTTTCTCAAGGTC ATTTAAAATGAACTGATTCTTTATTGGGTGATAGGTGGAAGGCAGGAATTGATTGAATTC ATACCTGTTAATCCCATATTAAATTCTTAAGGAGTTAGGAAGATCTGTGGTGGTTGTACT AATTCTACAGTTAAGGAAAGCTGAGAGTCAGAGAGGACAATTTAAGTGATGAGCTCTATT AGCTTATCTGTTTTATTGTCGAACCCTGAGCAGAACTTAGTCTCTGAACTTTAAATCCGG TCTTCTTTTCCTGTCTTGTAAGACAAAAATGGGAGAATTTCAGGCTTTTAAAATTGAACT TTAGTCAATGCTGTAGTTATGTAATTTTTATAAAGAGCCTACAATATATAGATTCTCTTA TTAAACATGTTAGCCATTATAAACGCCTTAGGCAAACAGGCATTCTTATTTTATGGTTCA GTTTCTGAAGTTCCTACTCTTTTTTGTTGTTCTTCCTGTGATGTAAGTCAGGAGCAGTGG TTTTGGAAGAAAGTATAAAGAAGGTGCAAACATCAGAAAAAAAATGCTTGTGTGTTTACT AGAACAGCATTTGTATAATAAGAATTACTTTGTGTTTTTGATCCATGAAATATACACATT CATTATGGCTAAAAGGAAGGACCTAATTTAAACAATGTGATATCAATGTTGGTTTAATAT CCTGATTTTTAAAGTCTTATATGACTTACATTTGATTTTTTTTTTTTTGCCTCTCTAGCC TTGTTAGAATTACATTTAATTTTGGTATAATAAATTCTGTTATATATACCTCCTTTTCTA TTTTATATATTAATATTTTACTATTTTATTTTCTTGTAAGCTTAATTCTGTTTGTTTCTC TTTTGGCTCTGTGACTGATCAAGAACATATTAAATGTATAAAGTCTGAGCTTGTTATTTT AAATTTGTAATGTCCAGGTTTTGTTATAAATACCTTAGTGTCTTTCTTTAAAAAGAAAAA GAACAAGTAATAAGTAACTCACATAGTGGGGAGAGTAAAACCATTTTAGCTGAAATGGTT TAGATCTAGGATAATTATTTGGGGGAAAATACATTTTCGAGATTTTTTCATATTTTTGCT TGAATTACCTTTACTTTCAGTGCAAACTTCTGAAATTTGATGTAATGTACTCTTTATTCC TGTTGTAACAACCTCATAGATGTCAGGTTTTTATTTTACAGCTGAAGAGAATAGAGGCTG TTGGACATTTTTTTTTTTTTTTTTTTTTTTTTTTTAGGTGGCTGACCCTAGGACGTAAGC AGCAATACTAAATGTTGCAACTTGTGGTCCTATGTATTGTAACCTGTTGGAAGTAGAGTA ATTAGTAGTACTGGTGGAAATCTTAAAAACATCAATATAAATAGGCAAAATTTCTTTTCT GATTATCAAGATCAAAAAAGGGAAGCTAAGGTCTAGGTGATGAGGTTCTCTATGTGAAGT CAGTTAATTTTCAATGAGCAGATCAGCGTTCTTATCTCTTCTCACAATAATGATTAGCAG TTCTTTGCAAAGGAAGTTTCAGTGAGTGCTTGAAAAATATGGGTCACTGAGGTCTGTCAT GCGAAACTAAGTGTTGGCCTGGCATCTCTGGAACTCAAATGATGGCCAAGCAGGCTTGAC TTCAGTGAAACAGGGTTTTAATGATTAAATGGAAATGGATGAAGTTGGTGAACAAATATA GTGACTTCAAAGCCTTTAACTTGGATTACTGGAGAATCAAGTGAAATATTTCACCACTGT GTTATCACTAAAGAGAATCAGTTCTGTGTGTGGTATTGGTTCTTTAAACATTATGTTCTA CACTAAGGACCCGAACTGTCATTCCCAGTTAGATAGTGTTTGAATGGGAAGTAATGTTGA ATTGTTTATTCTTAAAATTTTTTTTTATTTCCTTAATTATGGTTATTTAGATAATCCATC AATTATAGAATGAGAAGCCTATTTGTAAGATTGTGGAATTTCTAGTTTTCGAGTGTTGGG GGATAGTTAATATTATGACAAATTATTAACTTAGGGTGATTGCGAAAGTTATACCTCCTA GGTTGAGTTTAAAATGCTAGTCTCTTACTGTTGAATGTGAAACCTTGAATATGTCTAATT TTTATTGGCATGGATGTATGCATACAAATAGAGAAAGGTAAATTCTACTCATTTGCAGCT TCTCAGATATTCTGAAATTGCATTACTAGCTCTAAAATAAACATAATAGGTCAATTTGGT CTTGCATCGAAGCATTTTATGTAAGGAAAATGTATATTAAAAGTTATTGAATTTCTTGAT GGGCCATAAATCCCCTTAGCATCAAAGTTTGCAGCTTGGTTAAGAGTATGAAGGAGAAAA GAAACTTGACCAAGAAATGTTACTTAGAAAATATTTGTATGGAGTTAAATTACCATAATT TCAATTCCTCTTATGCCAGATTTTGCCCTTAAAAGTGAAAAGCAATTTGATTGATAGAGC AGTTGATGCAGGCAGGCAGAAACCTTTTTTTTTAAAAATCACTCTTCAGATTGCTCATGA GTTTGTTTTTTTCTTAACATCACTTACAATATTATCATTATGTAAATATTTGCTGTGGAA TCAAGTAGTATACTTGGAGTGATTAAGAAGAAAACAATCTTAAATTACTAAGTATGCAGT TCAAAAGGTAATGGCCTAGGCATCAAAGTCCGAAAGAGTGTCAGTTTTGTCCTTTTGTCT GTTTCTTCTCAGTCATATGAGGCTTCCATTTAAAAAGAATTCTCATATGTTTTTCTTGCA TTACTATTTTTTATTCTAGTGTAACATCTTTTTAAGTGGTTTCTTCATATGAGGTGTGTG GTTAGTAGAATTATGGCCCCTAAAGGATGTCTACATTCTCATTCCAGGAATTCATGAATG TTACCTCGCGTTGTAAAAGGGACTTTGCAGATGTGATTAAGGATCTTGAGATGCAGGATT GTCCTTGATAGTTATTTTTTCTCTGTCTGAAGGATTTCCTTTAACATTTCTTATCCTTTA ATATTCTCATTTTGCCTTTATTTTTGAAAGATGTTTTCGTTGAGTAAATAATTCTAGGTT GACGGTGTTTTAAAATTGCTTTTAAGATGTTCTACTCTTTTCTGGCTTGCATTGTTTCTG ATGAGAAATTGGCCATCAACATTGTCTTTGTTGCCTTGTAGATAATGTGTATTTTTTTTC TCTAGCTGTTTTAAAGATTGTCTTTAACATTGGTTTTAAGCAATTTAGTGATATATGACA GCGTCTTTTTTTTTTTCATGTGTTCAGTGGAGTTCATTGAGCTTCTTGGATTTATAGCTT TATTGTTTTCATTAGATTTGGAATAATTTTAACCATTATTTATTCAAATATCCTTTCTGT TTCTCCTTCATTGGGAACTCCAATTACACATATATTCGACTGCTTGATGTTGTTCCACAG CTTATTGATGTTCTATTCAATTTTTTCCAGTATTTTAAAAATCACCATTTAACTTTAGAT AATTTCTGTTGCTATGACTGTAAATCCAATCTCACATTTTTTTCTCACATAGACTAATGT GCTATTAATACTTTCAGTGCTTTTTTACCCCAAAGATGTAGTTTTCATCTTGAGAAGTTT AGTTGGGATCTTTTGAATATCTTAACACTTTTCAAATTTTTCTCTAGCTTTTTAAATACA CAGTAACCTTTTTTTAATGTTCTTTTCTGTTATTCTAACATGTAACAATTCTATGTTGGT TTCAGTTAATTGATTTTTCTTCTCATGGCCTGTATTTTCCTGTTTCTTTACATGTCTAGT AATTTTTGATTAGAGGCCAGACATTGTAATATTACCCTTTTTGGTCCAGATATTTTCGTA CTCTTGAGCTTGTTAAGGGATACAGTTAAATCACTTGGAAAGAGTTTGACCCTTTTATGT CTGTCTTTCTGCTTTCTCAGGTAGGACCAGAGCAGCATTTAGTTCAGGGCTAGTTTTACC TCCTACTGAGGCAAAAGCCTTCTAAGTTTTCTACCTGATATCCTGTTAATTATAAGGCTT TCTACTCTGACCATTGTGAACAGGAGGAGCTGTTCTAAAACTATGTGAGAGTTAGGATTA TTTCCTATAATCCTTTCAGTTGGTTCTCTAGTAGTTTACTCATATGCATGGGTTGATCGG TACTCAGCTGCACACTCAAGGAGTAAGCCTGAACATCTCCAGAATTCTTTGTCCTTGCAG CTTTCACCTCTTTGCTATTCTGCCCTGCAAACTCTAGGCGTCTTGGTCTCTTTGGTTTCC AGGCCCAGTTCCTCTACTTAGAGAGACTTCTAGGTTCCACCTTGCTTCATGCTTTTCGCG TCACAATCTGTAAGTTCTCCTGGCAATAAGCTGGTTCAATTGTATGATTATTTTATTTGT TTCCCCCCAGGAATCGGCATGCTTTGTTGCTTGTTCGGTGTAAAACCACTCTTAAATTTA TGTTTTCCATTTTTGAGTTGTTTTCAAATGTGAGGGTAAATCAGGTCCCATTTTCTCTAT CTTGGCTGGCAGAGTATGTCTCTTGCCTATGAGATCTTAATCTTAACTCTAAGCAACATT CTTAGTTTCTTAGTTCACAGGTGCTGCTGTAACAAAAATTCCCTAGATTGGGCAGTTTAT AAACAACAGAAAATTATTTCTCACGGTTCTGGAGCCTGGGAAGTCCAAGATCAAGGTGCT AACAGTATAGGTGTCTAATGAGGACCTGTTCCTCATAGATGATGCCTTCTAGCTGCATCC TCACATAATGGAAAGGGCAAGGCATTTACCTGGGTTCTCTTTTATAAGGTCACTGATCAC ATTTATGAGGGCTCTTTCCTTACACTTTAATCACCTCCCAAAGTTCCACCTCCTAATACA ATCACCTTGAGAGTATGTTTCAAAAATGAATTTTGAGATGATACAAATATTCAAACCATA CAAATATTCAAACCATAGCACTTAGGATTGCCTTTTGTGGTACTTGTTGCTGTTGCTAAC TTCATGATGTGTTTTAATTAATAACCACCCCCCCAGGACTTTTACTTTCATAATTGAGCC CCGAAAAATAATGTATTTATATATATTTAGGAGATTTATAATGACTTATCTGAGAGTCTG TAAAATATAGCAGAAATCTCAGTGTTCAGTCACAATGCTGAGAAATACTAAAATTAAAGT TGTAAAGGATTTACAGAACTGAAAAATGGTAGCATGCTTACTCACTTTTTGCATGCTAAA TTTATTTCTAGGCATTTGTGTTTTTTTTTTGGTAAGTAGATATTGTAAATGAGATTGCTT TCTTGAATTGTTTTTCAGCTCTTTCATTATTGCTTTATAGAAATGCTACCAAATTTTGTA TTTTGATTTTGTGTCCTACACCTTTATTAAATTCATTTATCAGTTCTAAGAATTGGTGGA GACTTTAGGTTTTTCTGTATATAAGATTATATTGTCTGCAAACAGAAACAGTTTGATTAC CTTGTTTCCAGTTTGGATGCTCTTTCTGTTCCTTAATTGTTCTGGCTAAGCCTTCCAGTA CTATGTTGAATGTGAGTGGTAAAAGTGGATATCCTTTTCTTGTTCCAATTCTTAGAGGAA AGCCTTTCACATTTCCCTTGTTCAGTATGGCGTCAGCTATGGGGTTGTCATGTATGGCCT TTATTGTGTTGAGGTACATTCCTTCTATGTGTAATTTGTTGAGAATTTTTATCATGAAGG GATGTCGAATTTTATCAAATGCTTTTTCTGTGTTTATAGAAATAATCATTTAGGTTTTGT TCATTTTGTGATATATCATGTTTATTGATTTGCATGTATTCCTGGGATAAAGCCCACCTG ATCATGTTGTGTAATTTTTTGATGTGTTGTTGGATTTGGTTTGCTAGTGTTTTGTTGAGG ATTTTTGCATCTAGGTTTATCAGGGGTTTTGGCTTGCAGTATTCTTTTTTTTTTTGCAGT GTCTTTGTCTCGCTTTGGTATTAGGGTAATGCTGGCCTCATAGAATGAGTTAGGAAGAAT TACCTCCTCTTCAATTTTTTGGAGTGATTTGAGAAGAATAAATGTGAGTTTTTTTATAAG TTTGGTAGAATTTAGCAGGAAAGTCATCCATTCTTGAGCTTTTCTTTGTTAGGAGACTTT ATTACTGACTCAATCTCCTTACTCATTATTAGTTTGTTTAAGTTTTCTATTTCTTCCTGG TTCAATCTTGATAGGTTGTATGTGTCAAGGGATTTATTCATTTCCTCTAGGTTTTCTAGT TTGTTAACATAAAGTTGTTCATAACAAGCGCTGATCTTTTGTATTTCTGTGTTATCAATT GTAATGTCTTCCTCTTTTATTTCTGATTTTGTTTATTCGGGTATTCTCTCTTTCTCCTGG TTAGTCTATCTAGTGGTTTATTGATTCTGTTTATCTCTTCAAACAACTGTATTTCGATTT CATTGATCTTTTGTATTTTTTTAGTCTCTATTTTGTTTATTTATGCTGTGATCTTTAAAT TTGTTTTTCTTTTACCGACTTTGGTAGAAGGAAAGATTTGCTTTTGCTTTTTAAATTCCT TGAGGTTGTTCATTTCAGGTCTTGCCACTGTTTTGATGTAGGTGTTTATTGCTGTAAACT GTTTTCTTAGTTCAGCTTTTGCTGTATCCCATAGATTTTGGTATGTTGTGTTTGTATTTT AGTTTAATAATTTTTTTTGTTTTCTTCTTAATTTTTCTTCATCACTCTACTGGACTCTAC TGGTGTTCAGGAACATATTTTCATTTCCATTTATTTGTACAGTTTCCAAAGTTCTTATTT ATTCCTAGTTTTATTCTATTGTGATATGATTTCAATTTTTAAAAATAGGTTGAGGCTTGT TTTTGGGTTATTATCTGGTCTATCCTGGAGAATTCTCCATGTGCTCATAAGAATGTGTAT ACAGTAGCTGTTGGATGAAATGTTCTGTAAATGTCTGTCAGGTCCATTTGGTCTGTGATG CAATTTGAGACTGATTTTTGTTGCTGTTGATTTTTCTATCTAGATGACCTGTTCAATATT GACAGTAGAGTGTTGAAGTCCTCAACTATTATTGTATTGGGGCCTGTCTCTCCCTTTTAA TATAATAATATTTAGATCTATTAATTCATGCTTATGTATCTGGGTTTTCCAGTGCTGGGT GCATATATTTACAATAATTATATTTTCTGGCTGAATTGATCTCTTTATCATTATATAATG ACTTTTTTTCTCTTTTTATAGTTTTTGACTTAAAAATTCATTTTATCTAATATAAATATA GCTACTCCCATTTAGTTTTGGTTTCTCTTTGTGTAGAATATTCTTGTTCATCCCTTCATG TTCAGTCTGTGTGTTCTTTATAGGTGAAATGAGTTTCTTATATGCATATAACTGGGTCTT GTTTCTTTTTTTAAAAAAATCTATTCAGCAACTCTATATCTTTTATTGGAGAATTGAAAC CAACCATTTATATTCAGGATTACTATTGATAGGTGAGAGCACACTCCTGTTATTTTGTTG TTTTCTGGTTGTTTTGTGTATCATTTGTTCTTTTCTTCCTCTCTTATTGTTTATCTTTGG TGGTTTTCTGTAGTGATAGGGTTTGATTCCTTTCTCATCCTTGTGTATCTGCTCTGTCAG TTAATTTTATACTTTCATATGCTTTCATGATGTTAAATTTTGTCCTTTTACTTCCAGATA TAAGACTCCCATAAGCCTTTCTTATAAGGTTGCTCTAGTGGTAATGGATTTCTTCAGTTT TTACTTGTCTAGAAAAGACTTTATTTCTTCATTTCTGAAGAATATTTTTGCTGGGTACAG TATTCTTTGCTGGCAGTTTTCTTTCAGCATTTTGAATATATAATACCATTTTCTTTTTGC TGGTAGCATTTCTGCTGATAAATTTGCTGTTAGTATGATGGGGAGTCCCTTTTTACTTCA TGCTTTTCTCTTGCTGTTTTGAAAATTCTCTCTTTGTTTTTGACTTTTGACAGTTTTCAG TAATGTGCCTTGGAGAGAACTTTTTTGAATTAAATTTACTTAAGGATTTTTGAGCTATCG TATCTTTTCCATGACTTGGGATATTTTCAGCTAGTATTTCATTAAATATATTTTCAATAC CTTTTTCCATCTCTTTGTTGAATTCCTATAATGCGAAAATATGTTCACTTATTTGTGTTC CATTGTCTTATTGGCTTTCTCCATTCATTTTTATTGTTTTTTCTTTTTATTTTGTTTGAC TTGACTATTTCAAAAGACCCATTTTTATCTTTAGAAATTCTTCCTAGAAAAATCAGTCTC TTCTGCTTGATCTAGTCTATTGTTGAAGCTCTTAATTTTGTTTTCTTATTTCATTCATTG AATTCTTTACCTCAATATTTCTGTTTTGTTCTTTTTTATATCTATTTGTGTTGAATTTCT CATTTAGATCATGAATTGTTTTTGTTTTCATTGAATTCTCAGTCTGTATTCTCTTGTATC TTGCTGAGTTTTCTTAGGATCATCATTTTGAATTCCTTTTCAGGCACTTTATAAATTTCC TTTTTTGGTGTCAGTTACTGGAGAATAGTTTTCCTTTGGAGGTGTCATATTCCTTGCTTT TCACTTCTCTTGTGGTCTTACATTGATATCTGTGCTCACTGCTTCTGATTTTATGTAGTT TTTGTAAGGATAATTTTTTTTTTCTGTTTATGTGTCTTGTAGTGCTGGTTTGGTAGAGTG TTTTCATTTTAGTTCTGGATTGGAACAGTATTGTCTTCTTGTGCTTTCTTTGGCGTATTC AGTGTCAGCTGTGTCTGCAAGTGCCTCAGTGGCCTGGGCTGTGGGTGTTTCTGTAGGCAG TGGCACAGCTTTTTTGGTGTGGGGCCTGCCAGGCAGGCTGACTCTCAGGTCCTTGGGAGC GTATAGGGGCTCCCTTGGTCTTGAGGGTAGTCTCCTCTCTATGCTGGGCCACTGCTTCTT GGTATACAGGTTGCTGTATGGGCTTGCATGCCTGAGTCATTGCCGTACCACTGGGTTCAG GGTGGCATCATTGTGCTGCAGCCTTCTCTGTAGGCATGGTGAGATAGTGGAGGGGTCACA GGGATATGGAATTGCAGGGATATTAGGCCCCAGGGAAAGATGCACTCTGGTAGTAGCTCA TCTCTCAATATGGCTCTGTGCCGCAGCAGCCTGGGTCCTGGGGGTTGCGGGGGAGACCCA GCATGAGTTTTCTCTGGGGAGCAGTGCAGCCATGTTAACTTTAGGCAGCTCCCTGTACCC TGACTAAAGTGTACTCCGCTTAGTCCTCTGTGAGGACTGTGGGGCTTTCCTATAGCAAGC ATTGCAGGCATCCATGGTGGCAACGGAGGCTACCTCTTACCTTTTCTCCACAATGGAGAG TTCCTCTTGGTTCAAGCCAATCCTTGCTGGATGCTTTACTTCCTTCTCTGTGATACTATC CTGAGTTTTTGTGTCCAGAGGCTTTTTGCCACTTCCTTGCTAACTTGCAGTGTTCTCTCT TAGACATTCTACTCAAAGTGCAGTTATCTCTTTGTTGTTTTGGTTCTTTGTGGAAGAGGC TAGCACTGGACACCTCCACTCAGCCATTGATGATGACATGTTCTTTGCTTTTGACTACAT GTACTTTGAAAATCAGAGACAAAGGGGTGTTTTAAAGTTTTCCTTTCATGTCTCTTAGCA ACAGCAAATAAATTTTCTTTGGATTGCAATTTTATAAGTGATAAAAATGTTTAGCAATAT GATGGGGTGATTGAAATTTCTTGATAAAAGTTGCCAGTTTTTCTAATGTTTGCCGTGAAA AGTAGATTGCATATTTGAGTACTCAAACACATATATTTAATTGCTGATAGTATCCTATGC CACATTTTATTTTGTACGGCTCTTTCTTTTGTCTTTCAAGTAGAAAAATAAAAGTCTTGT GATATTTTGTGATAAATATGTGACCAAAGTTGAAGGAGAGTGAAAGCTGAACACTATATT TTAAGCTAATCTTAATTTAAAATATTTTTTGTTTTAACTTTATATTTTTGTTATAAATTT ACATACAACATAGTAATTTTGAGTATTGTTTTGGTCACTCTTCTTTTTCCTTTTCTTTTT CTTGACTGTTTAAAAAATTAAATGGTTTTGAAGGAAAGTCACAGAATGCTTTGCTCTCAT TTATTGTTTATTTTCCATGGCTATAAATCAAGTCCATAAATGAGAAAATGGTTTTGGCTT TTTCAGTGAGGCTTGAAGTGCTTGCTGATCATGGTGTCTGAACCAGTGGGGCTGTCCTTG GCTTTACAGGTGGCAGGCAGTTAATATTGATCATCTCAAATATCAGCAGTATATCTGGCA TTTTATGGATGAAGAACCTATTTTATGGATGAAGAACCTAATATTCAGTGAGATCACTGT AAGCTGCTCCTTGTCACTCAGTGAGCAAGAGGTTGATTTTTTGAACTTCATGACAACTAT GACATTATGCTGTTTTCTACCTTTTCCCCTTGGACATGGGTAGAGACAACTATTACCTGT TCAATTGCCCCTTGTTCATTGTTATGGAGGTCAGTGTACCATCATCCAGAGGAATCACTG GCCTTTCAATTACAGTCCCAAACTAGTCTGTTGGGATGTCCCACAGCTTTATAAAAAGAG GCTATGAAACCCATTTGATATGAATTTGGTAAATATGGTTATAAATGGTTCTGGCTATTT ATTTGAGAAAAATCTACAAAATGGGACACTTTTAGGAATAATCCCTTTTTTATTTATTTT GGCAATAAGTTAAAAATATGAAATAATATACTTTTAGGCATAATTTTGTCCTTTTCATTT TATATAATATTGGTATTAAAGAGGAATAGGAAAGAAGGAATTACTCAAGAATATGACGTC CCTTTTTTTAAAATTATTTGATTTACCTATTTACATTTTTTGCTTCAACTTACCTAGCCA TCAGAGAAACTTTTATTGTAAGCCAAATCTTCCAACACTTCACACTCACTGATTCATCTC CTGGGTATCGTGAATATTCTGACCATTTATATCAGTGAAAAAATTTGTATGTTTGCAAAT TGATAGAGATGCATTTCATATTTAGGATTTTATTAGCTTTTATGCTTCATCTATGCTATT TAAGCAGGTAGGCACATGTGAAAAACTGATATCAATTAGCCATTACATAATTATTTTGCA TCTGTTATGTCCATGTGCCTAGGAACACAGTGTGAATAAGCCAGGCCTAGACCCTCATCT CTAAAGACTTGCAGTCAAGGAATTGCAGGAGCTTTTGGAATGTTGAACAGATGCTGAGCA GAGCCTCTTTTCATCCTGTCCTCAGAGGAGCTGGTCAGTCAAATCTGCCAAAATTCTCTG CCTCTGTGTAGCCTATTCCTTGGGGGTTTAGGAAAGAGGGCAATAATCCTCTGAGTCAGA GAGCAGACCATCTCTCATCCTTCACAGCAGCTGGATGCTACTGTCTCCCCTTGCCCCCCC GATGTATGCCCTGGGCGGACAGTACTAAATATAATGGAAAACCAAAATACTTAACTGGAA ACCTTTATCATATTAATTAGATCTCTCTTTGCTTCAGGCTGTAAAACTGATTAGTGTTCT CAAAGTCCCTGAGAAGACTTTGCTATCTTCTTTGACTGATCTATGAAGGAAGGGGTAGAA GACTGGTTGCAGGGTAAGGCTGGCCCAGTCTAGGGAAAATCTTTTTTGTTTTTTTTGAAA GGTCAATATATTTTTTAAAAATCCTTTATTTCCATAGGTTTTTGGGGAACAGGTGGTGTT TGGTTACATGCATAAGTTCTTTAGTGGTGATTTCTGAAATGTTGGTACACCTTACCCAAG CACTGCACACTGTACCCAATTTCTAGTCTTTTATCCCTCAGCCCCATCCCACCTTTTCCC CTGAGTCCCTATAGTCCATTGTATCATTCTTATGCCTTTGCATCCTCATACGATGTTTGG TTTTCCATTCCTGAGTTACTTCACTTAGAATAATGATTTCCAATTTTATCCAGGTTGCTG CAAATGCCATTTTTTCATTCCTTTTTATGGCTGAATACTAATTCAATGATGTGTGTGTGT GTGTATATATACATATACACACGTGTGTATATGTGTGTATACACATGTACACACTTGCAT ATGTGTATATCTATACATGTACACACGTGCATATACATACGTGCATATGTATATATGTAT AGATACAAACATGTACACACACACCACATGGTGTGTATATATATATTCAATTATATATAT ACATACACATATATATATACACACACATATATGTACACCACGATTTCTTTATCCAGTCAT TGATTGATGGGCATTTAGGCTAGTTTCATATTTTTGCAATTGTGAATTTTGCTACTATAA ACATGCATGTGCAAGTATCCTTTTTGTATAATGACTTCTTTTTCCTCTGGGTACATACCC AATAGTAGGATCGCTGGATCAAATGGTAGTTCTACTTTTAGGTCTTTAAGGAAACCACAC TGTTTTCCACAGTGGTTGTGCTAGTTTAAATTCCCATCAGCAGTGTAAAAGTGTTCTCTT TTCACCGTATCCCCATCATCATCTATTATTTTTTGATTTTTTTGACTATGGCCATTTTTG CAGGAGTAAGGTTGTATCGCATCATGGTTTTGATTTGCATTTCCCTGATCATCAGCAATG TTGAGCATTTTTTCATATGTTTGTACCCCTTATCTTCTGATGTGTTTGTGAGAAAGGCCC TTACTTGGAATGTGTGTGCATTCTTCTGTTATTCACGATTTCAGCAAGCTTGCTTACCTG GTGTTTAAGTCCACAGCTAACCAGAAGTGACACAGTAGAGGCTTGGAGAAGGGATATTTA GGCCACTTACTCTCTGACATTATAAGTATACAGCACAGTTGAAACCTGATGGGAGAATAA TAAAAAGGTGTAAAAACCTGAAAACTGATTGTACTCTGGTAATAGGAGGTAGAGAGGCAG CGGCAGCTGTGCAACTCTTTGGAGGCCTGCAGAATCATAATTCACGTGCATAGTGGTGGG TTAGGCCATGTCTCTTGTGCCTTAGGAAAGGTGGGGAAAAAGTGTTTTAAAATGTCACAG AAAGCTTTCTATGCTTAATGGTTTACTTACATTTTGTTGTTGTTTTGCTTAAGGGTATAA ACTTTAGTTTTTTATGGTGGACTATTCCCAGACCTGAGGTTTTAGTGTACATGTCATTAA TCAGCCTCTCCCATAAGCTCTCAAAAATTATTTGGATGATTTTTTCTCCCTTTAGGAAAG TTATGAAGAGAAAGAAAAGACAGTGATTTGTCATCTTTTAGGGGAGATATATATATATGT GTGTGTCTTTTAGGGGATATATATATGTCTTTTAGGGGATATGTATATGTGTTCTAGGAG ATAAATACATGTATGTCTTTTGGGGTGTATGTATATGTATCTTTTAGGGTATATATATAT ATCTCTTTTAGGGGATATATATATCCCCTAAAATTATATATAAAATATATAATTTCCCAT CCCCCAATTGGCTTATTTGACTTTAATGTTTCAGCATACTTTTTTGAGCCTCTGCTGAAT GCTGTGCCTGTAATTGCATAGCTAAGACCTTAGACAGCCACTGTCAGTTTAAAGTCAATA CTTAAATACTTATAGTTAATAGATTACTTATAATATAGCATTTATAAAGTTCCTGCTATC TAGAGACTCCCTGATCAATTGTGCTTGGAAGTGTGAATACCCAGGGAAGGCAGTGACGTC ATCTGATTCTCAAGTAAGTGTCTTAAGGGACTTACTTACCTAGGGACCTGTAAGTGCAGA GGCTTCAATGTTGGAAAGGGCATGGTATATTTGGAGAAGACTGGGAGGTTTATGTGATCA AAATGCTCAGGGGACAATGGGGAGGGAATCAGAAAGAAAAAACAGTTAAAATCTTCTCTC CTGGAGTGATCATTTTGCAGTCAGTGGCATTCTACTCCCAACAACTTTCTGGCTATCTGA GTTTAGGTAGTTTACCTTGATTTCCTCATCTGTACAGTCAGTGGTGCTAACAGTGAGACT CCAGTCTCTAGGAGAGCTTTTCTAAGGACTAGATGAGGAGATACAGAGGTCTTGAGCACA CTGCCTGAAATTAAGTGCTCTCTACAGGTTATTCTCTCCTTTTTCTCGTTCTGCTCAGGA CCCCTGGTGACATCCTTGTTACTTTCATCCTGACTGACAGATGCCAAGTAGAGCCCTAGG ATTTGATACGAAAGGGCTGGCTTGGGAATGCCTTTAAGTAAGCAACATTTGGTTTGCTCC TTCAGAGAGTTCTCCTTGAGATCACCACACTCTAAACCTGGGTCACATTTGTTCCAAGGC CTTCTAAAGCTAATTCTGTATTATATAGCACTTATTTTAATGTTCCAGTGGGTTATCTGT TCACCTCAAAGATTAAACTGAGAACTCCTTCTGGCAAGAATGAAAGGAAAGGAAGAGGGG TTGTTGGCCAGCAAAAACAGAATAGAAGAGAAACTAGTGCCCAGAACGCCCACATCAGCA CACCACATCCACTCCAAGGAGGCTTTTCAACCCCAAACATCCAGCCAGGGTTTTTAGGTA AGGATTGGTCTTTGTGTTCAGTGTTTGTCTTGGACATCTTCACATTTTTTCCTACTCCTG TGCTCCACTCCCTTCTCCCCCTTGCCTTCCCTCAACTCAGTGGGTTATTGGAAGAAAGAA GGCAAGAATCACATCTGAACACCTTTTGTAAGAACGACATGATATTACCAAGGCCTCTTT AAGGAAGGGGAATTTGGCCTCAAAGCCAACTGGCCTCTTGGCTTGCCATGGAGTGGGTTT GGAAGCAGCTACTGCTCAGGCTTTCCCTCCTTTACCTTTTGTGTTCCTAAGGAAAGATTT TTGTAAAAAGACAAATGAAGACATTCTACTTCTTGGGGTTATTCCTAAGAATTTTCAGCT TGGGCCCTTTTAATTTTTCCCTTCTCTAAATAACAAAGGTAGGGAAATGAACCTGGACAG GTTTGATAAAAGTACACTAGAAATGCTGTTCATGTATGTTTAAAAGTTACATTGAAAGGG AGAAAACAGCACTTCAAGTTAAGTAAGTTACATGTAGAATGCAGTCTTTACATCTAATAA TATTCATTTGGAGATGGTATGACTCAATGTTCGTCTACAGTTTCCTGGAAGTTCTTCAAT CTCAAACCTCTTTAAATTATACAGTGTTGCATTTTTCTTCTTGTTGCAGTTCACCTCATC ACAAGGAATATATGTACATGCCACAATACTTAAACATGCAATTAAAATGGAATGTCTTTT TAAAAAGTATACTTTAAGTTCTGAGATACATGTGCAGAATGTGCAGGTTTGTTACTTAGG TATACACATGACATGGTGGTTCGCTGCACCCATCAGCCCATCATCTACATTAGGTATTTC TCCTAATGCTATCCCTCCCCTAGGCTCCCACCCCCTGGCAGGTCCCAGTGTGTGATGTTC CCCTCCCTGTATCCATGTGTTCTTGTTGTTCACCTCCCACTTACGAGTGAGAACACGTGG TGTTCGGTTTTCTGTTCCTGTGTTAGGTTGCTGAGAATGATCGTTTCCAGCTTCTTCTAT GTCCCTGCAAAGGACATGAACTTATCCTTTTATATGGCTGCATAGTATTCCACGGTGTAT ATGTGTCACATTTTCTTCATCCAGTCTGTCATTGGTGGACATTTGGGTTGGTTCCAAGTC TTTGCTATTGTGAATAGTGTTACAGTAAACATATGTGTGCATGTGTCTTTATAGTAGAAT GATTTACAATCCTTTGAATATATACCCAGTAATGGAATTGCTGGGTCAAATGGTATTTCT GGTTCTAGATCCTTGAGGAATTGCCACACTGTCTTCCACAATGGTTGAACTAATTTACAC TCCCAACAACAGTGTAAAAACATTTCTATTTTTCCACATTCTCTCCATCATCTGTTGTTT CCTGACATCAGGAATGTTTTGGGGGAAAATATTTCTGAGAGTATCCCTCAGATAAAACTT CGGGAACTATAAGTTGTCAGTTGCAGTAAGCAGTACATAAGCAAACATTACTGCCTAGTG AGAGAGCATGAAAGTCAATGAATTTATTTGTTCTGATGAAGAGCCTTCGTTGGGAAATTT ATTTAAAGACAATAGATGTAGTATCCAGTTCTGATGTCAGGGTTAGAGAAATTATCTTTG GCTAAGGTTATCTCCTATTTTGCCCTGTAACATTGAAATGCATGCTGTTATGTGATGCCA GCATGTGCTTTTCCTGGCTTGCTGCCCTCTTAGGTTTGGCCCTGGCAGATTGAAAGGTTC TCCAAGTTGGCCAACCCTTGTGATGAACTCTTTGAGCATGATAGGCTGGAGGCGGTGGCA GGAGCAGCCAAGATGACTGGATTCTGGTGTTGAAAGAGGGTGAAGTGAAACTATTCATAA CAGATGCAGAGTTACTTACTTCAATTGATCCCATCTTTGTAGGCTTCTTTTCAGCTTTAG AACTGCTTCTTACTTTGGCTTTGTATGTTTATCTTTCCCTTAACTTTCTAGTCATAATAT ATTTGAGTCAGCAGAGCTTGCAATTTGTGCCTAATTTGCACAAATACAGTTTGGAAACTT AAAGGTCAGGGAAGTTATGTGCAAATAGGAAATTTAACTTAAACCAGAACTGTGTATTTC CGAGACCTGAACCCGTATAACCTGGAATCACTAAGCCAACTGCTAATTTAGCATTGACAC AGCCTAAACAGAAACAAATGGGTAGCAAGTGTAGTTTAGGGTGAATGTTTTGAAATCATT TCTGTTTGGGGTTTGTAAAAATAAAATGCTGCTGATCTTGTTTTGCTCTTTTTGGGTAGA AATGTTTGCTTGATTCTGGTCATTTTTAGTACCCAGCAAAGGTATCCACTTCACCAGTTG CTCATTTCTTTACCATTGCTGTGTATCCAGTGCATTCTAGACTTGGTTGCAGCTCTAGAT CAAACAATTTGATTTGAGAATCTGGCTTCCCAGTTTTCTTATTTTTGTTTCATAGACCGC AAGATTTTAGAAAGGCATGCTGACCAGTTCTGAATGGTGTCCTAAGAATTCAGGGACTTG CATAATTTTATTGGAAGAAAACTTTGTTTTCCCTGGGCCTATCCAAATACCAAGCTCATG GAAGAGGCTTAAATACTTTTTCGTTGCAGTTAGATAATCAGGTTTTATATTTTTATTTAT ATAATTTTTATTTCCAACTTTTATTGTAAGTTCAGGGATACATGTGCAGGATGCACAGGT TTGTTACATAGGTAAACATGTGCCATGGTGGTTTGCTGCCCACATTGTCCCATCACCCAG GTATTAATCCCAGCATCCACTACTTATTCTTCTTGATTTTCTCCCTCCTCCCACCCCCGC CCTCCGACAGGCCCTGATGTGTGTTGTTCCACCCATATGTCCATGTGTTCTCATCATTTA GCTTCCACTTGTAAGTGAGAACATGTGGTAGTTGGTTTTCTGTTCCTGTGTTAGTTTGCT AAGGATAATGGCCTTGAGTTCCATCCATGTCCTTGCAAAAGACATGATCTCATTCCTTTT TATGGCTGCATAGTATTTCATCATGTATATGTGCCACCTTTTCTTTATTCAGTTTATCAT TGACGGGCATTTAGGTTGATTCCATGTCTTTGCTATTGTGAAAAATGGCGCAGTGAACAT ATGTGTGCATGTGTTTTTATAACAGAACGATTTATATTCCTTTGGGTATAAAGAAATGGG ATTATTGTGTCGAATGGTATTTCTGCCTCTAGGTCTTTGAGGAATCACCACATTATCTTC CACAATGGTTGAACTAATTTGTACTACCACCAACAGTGTAAAAGTGTTCCTTTTTCTCCA CAATCTCGCAAGCATCTTGTTGCTTTTTGACTTTTTAATAATAGCTGTTTTGACTAGTGT GAGATGATATCTCATCGTAGTTTTGATTTGCATTTCTCTAATGATCAGTGATGTTGAGCT GTTTTTCATGTTTGTTGGCCGCATGTATGTCTTAAGAAGTGTCTGTTCATGTCCTTTGCC CACTTTTAAGTGGGATTTTTTTTTCTCGTAAATTTGTCTAAGTTCCTTATAGATGCTGGA TATTAGATCTTTGTCAGATGAATGGATTGCAAAAATTTTCTCCCACTTTGTAGGTTGTAT GTTTACTCTGTTGATAGTTTCTTTTGCTGTGCAGAAGCTCTTTAGTTTAATTAGATCCCA TTTGTCAATTTTTGCTTTTGTTGTGACACGTCTTCATCATTAAATATTTGCCCCTTTCTA TGTCCTGAATGGTATTGCCTTAATTAAAGACTTGTTTAATCGAACTGATATGGACAAGCA GTACACTATTTTTATAGATGATCTTGTTGGAAGCCAGATTTAAGGAGATTGCCTGGAGAC TAAAAATACATTATTTTCATGGGGATTTCATTTTTAATCTAGTGTGAAAATAGTGTTGAT ATGAGCAAACTTTATTCAGTGTTGTAATTCCTCAAATAAAATATGCATGAAATTGAAAAG CACAAAAGTCTTCAATGTTTATCTCTGTCATCTATATCTATGTCTACCTGTAGATATATA GCACATATCTATATGTGAATATATAGAGAACAATGCTAGAATGATAAAATAGCAACAGGG ATTATATCTGGGAGATGGGAAATGTGAGAACACCAGATAGCCAGAGGTAAACAATACTAC GCCTTTGATCCCTCAACATGGAATGAAATGTGGTGAGCATTTTCCATTGTCATTAGGTAG TCTTCGATGGCATGGTTTTCTGTTATTATTTATTCTGTTATGTTGTTATGTTATTATGTT GTTATGTGATATTCTGTCATATAGGTATTTTGTTTATCTTGGTGCTTAAGAAAGCCAAAG TAGATAATTCATATTTGACTTTGGATCCTGTGTTTTCTAAGTTTTTACCTCAAACAAAAT GATGACACAACACCTTGATGTGGCCTGAATTTTGGAAGCTGCATGTTCTTCCTGCTTGGC TCTCTCCCATTCTGCCTCTACTTTCTCTTCCCTCTCTGCTTTCTCCAGTTGTAAATAGGA CTATCTTAGTGGTTATGCACTGCCAACTTTTGTAGCATTGGGTTCAGTTTATAGCATGTG TAAGTGGTCAATGAATGTTTCTTCCTCTAAATACTTTTCTTACAAGAAGAGGTAGTTAGA TTTTCATCCAACACAAACTCCAATCTGGCTTTTGTCATTACTGAAGATACTGATTTTGCA AGGCAGAATTCCTGAAGCTTTTGAGCCCTTTCTAGGCAGTTCTTTGCGGTTAGATGACAG TGCTGGATAAGAAGGAATAGGTATTTCTCAGGCCCAGATGGTCTGAAAGAGGTTTTGCTA ATGCTCCTAAACCAATTTGATGGATTATAATTCTTTGTTTCTTTTGGGTAAGCATGAAGA GTGTAATAGATGGCAAGGTAAGGGCTGTAGGGTTTCTCTTCAAAGACTTTATTAGGCGGT GTGTAATAACCAAAGCAAATCTCGCAATGAATTCTGCCTCACATGCAAACCCTTATTAAT GAGCAGGGCCCAGTTGTATGACTGTTCTCTAATGTCAGTGAGGTGCCTGCTGTCTGTCCT TAGGGTACTCTAACAGATCTGTGCATGAGATGTTTATTTGAAGCAGAAAGGGAAGTTGTT CAAGCAGCGTGATTGACTTCTGATTATTCTTCAGCATCAAAGTCCTAAGCTTAAGGGTAC TAATCCTAAGGGGTTGAGGCATTGGACATTTTTGGTTTGTAGACCCTGTTTAGTTAAAGG CAGGAGTACCCTATAGTATTTCTGACCACTCTACATCTGGCAAAATTCACATTTACCCAT GAGAAATAATTTTTAGCATCCATTTTGCTAACTAACAAAGCCTCCGTTGTTTATGACAAA TAAAATTTGGAGTCCGCTGACTCTGGAGTGTGAGCCTCCCTAGGAAGGCTTTCACATACT CATGAAGTACCTCTGGGGTATGTTCTCAGCTGGAATAACCCACCACTCCTGGGAGGAGGG TCAGAACCATCCTACAGGCATTTGTTACATGCACTGTGCTGAAGTGTTTTAAAGATAATT ACAGACAGCACAACAGAAGGATGTTTTGTGATTCTTCTGTGTGAGAATCAGATTGGGAGA TGGATTTGGACACAAAAATGTTGAAATATAAGGAACATTTTTGTGGTTGATGGGAAAAAT TGGAAACACATTTGATGTTAAGACTGTCCTGGAAAACCCAGGACACGTGGCTACCAGAGA ACAGGCTCTTTCAGTTTGCTTTTTTCTGGGAAGTGAGATAAAAATACCAAATGCAGTGTG ATAAACTTTTCCTTCCCATAAAATATACATGTATTGATATGTTAAAGTACTATGTGTTCA CAAATACAAGCTTAATTTTATACATATGCATAAGTATTAAAGTGTATACAGCTCTTTCAC CTTCAGGAACAGTTTTCAAGCATTTTGATTTCAAGCCCCTTTTACATTTTAAAAATTGTT GAGGATCCCAAAAGAGATTTTATATGTTTGGTTTATAGCTATTGATGTTGACTATATTTT CAGTTAAATTGAGACAATTTTAATAGATTTATTAATATTTTTAAAAATAACATAAAACTT ACTGCATGTTAATAAAAAATTGTTTCACGAAAAATTCCCTATTTTCTAAGACAAAAAATT CAGTGAGATGAATGATATTGTTTTACGTTTCTGCAAACTTCTTGTGTGTCTGGTGTACAA GAAGACAGCTGCATTCTCATTTCTTCTTCTGCATTCAATCTGTCCCTCTCACTCTTCAGG TAGCCTCTGAAAAACTCTGTGTACATTTGTGTGAAAACGAGTGAGCAAAAAATGACTCAG TATAATTTTAGAAATTATTTTGACCCCTCAAACCTTTTTTTTTTTTAATTTTACTTTAAA TTCTGGGATACATGTGCAGAACGTGCAGGTTTGTTACTTAGGTATACATGTGCCATGGTG GTTTGCTGCACCTATCAACTCATCATCTAGGTTTTAAGCCCCACGTGCATTAGGTATTTG TCCTAATGCTCTTCCCTCCTGTTGTCCCCCACTCCCCAACAGGCCCCGGTGTATGATGTC CCCCTCTCTGTGTCCATGGGTTCTCATTGTTCAACTCCCACTTATGAGTGAGAACATGAC CTTGCAAACCTTTTAAAGAGTATCAAAGATCCCCGGGTCCCTGGATGACACTCCGCACAC TGCTCCGTGGTTTCAGTGTTCTACCACCCATTGTGTTATTTGGTCCTAATTGCCAGCCCT GAGAAGTCATTACTATCTCCATTTTATAGTCGAGGCAAACTGGGATTCCAGAAGGCTTGC CTTTGAGTATTATGAAAGTTCCACTAGTACTGATGCAGCCAGTTTTTATTTTTATTTTAT TTAGTGTTTAAAGGTTACAGTCTTATTGCCTTGGAGATTTATGAAGTAGTTTTTTTTTGG TTGTTGTTGTTGGTTTTTTTTTGTTAAGAAATAGGGTCTCGCTATGTTGGGTAGGCTCTC CTTGGACTCCTGGACTTAACGCGATTTTCCTGCTTCAGCCTCCTAGGCAGCTGAGTCTGT AAGTGTGTGCCACTGCTCCAGGCTGCAACCAGTTTTTAAATGAGAGTCTTCTGATGGCTT TGTTTCTGTGATTGTTCCTTTTCAATGTATTACCATAAATTGTATTTACCTTCTACTTAG AATTCAGGGAGAGGGAAGCTTTTATCTTTTATTTATGCAAGTTCACAATAGAAGTTTGCA GAGCGTTATAGCTTTGGATGATTTTTCAGACATTTTCATATCAGGTTTTAATCTGTAATA TTTTAATATTTGAGCATTTATGCTAAGAATAAGTGATAATATTTTACAATTTTTTGGTGT GTGCTTTAAATAGGTTATTTGAGGACAGTTGTTTTATTTTCTCACTTTATGTGGATTAAA TGTCACATCTTTGAAGAGCCGAGTGGATTTGGCAGAGTGTCACCTAGCCCCTAATTAACT GTGTTTACACAGTCCACAAACTTGTGCCCTCCATGGAGGTCAAAGCAAATTTGCCTTCCA AACCTTTCAGGAACAACTCTGTTATATAGAATCTGAGTTTTAAAATTTCAAAATTCCAGT GGAATGATACTTTTTGTATGGCGTACTGATCCTGTAATAGTTAATACAAGTGAATAGTGA GAAAAATGATAATTACTAGAAAAGCAGCAGACATACAAAATAAAAGCCTGGATTTTTATT TCATTCCACATGCATACAACTACCTTTTCAAGTTACTACAAGAATTTCTAAATACTCTTT AATTTCTGTATCATTCTGTATTATCTGCTTGCTCTCTGGGAACACACGGTTCATGTACAA GCAAGGATCGCACTTTGAATAGCACTGATGCCCATTATTGCCACTGTGCATTCCTGCATA ATTCAAATCTGGAATTTTAGCTGTCTTACTTCGTGCCTCCCATCCTCAACTTCAGTTTAA ACTAGAGAATTATTTGTTCTTCTCTGCCTCCCCTCCCAAAATACTTAAATGGTGTTATAC ATTGTTACAAAAGTGAGGGAGATATGTATATACAAAATATACTGTTTAAAAGGATCAATA CTGTTACAAAAAAACCGCACTCAAATGTAAGTTCAGATGACATTGTTCTGAATCTTATTT TCCTCACTTAATAAGGTATCACTTCTGGCTCACTTGCTTGAGGGGGACAAAATAATGAGA GAGAAAGAAAGTTATCCCAGATGTCTTGAGTTAAGGGAAAGGATGAGTGATTGCTTATTT TTTTCTTTATGGGATTCTTACATAGTTGTTTTAACGAAGACTTGTGGATGAGGGGAGGAA CAGAGCAATAGCTGGTCAGAAGTGGGAGCAGCTGAGAAAATGAGGGAAAACAGAAACAAA CTGTCGGGCCAGAGGCAGAGGGGGCTCTCAGAGACAGAGAAAGCAACTTTGATCAGATGA GGTTGGTTTCCACAATGTCCAGCTATCTGCTGGACCTGTGATCCTCACAGTCAGTGCTGG GTTTCCCTGAGCACTTACCATTCAGTGGGTGCCTACCATGTGCTAGACAGGGGAGGTTCC TTTTCACACACCTGCACTTAACCCTCACAACAGACCCAAGAAGTGGAATGAGAGAACAAT GAGGCTCACAGGGGTAAAGTATTTGTTTAAGGGCACCAACTAGTAAGTAATGAGACTGGG ATGGGAACCAACATCATTCTGATGCCAAAGCCTCTTGCTTTTTCCAGATTTGCTACAAAT TTAAAAGATAGGGAGTCGAGACTGAGGAGGGCCCATGAAGGAGCAGTAATATGCCTGGTA CATTAGCCCCTGTAGCTTCCTAACAATTCCTACAGTACTTCTCCAGATAAAGAATATGGA AGACAGTGAAGTATCTGTTTCCAGAAACATTTTTGAGGAAGTCAGAGAGAGGCCAAAAGG GACTTAAGTTTCTTCAGAGAGGAAGTTGAGAAACTCAAGTATAGCAAACCACTAATGCCA GATGTTATTTATCCAAAGGTTTTTGGCTATATTGCAATACTTTCTGGATCTCTGCTAGTT CTCTGCAATCTTTCTGAAGCTGCTTTGAGTTTTGAAAATATACATACCTGAATTTGAAAC CATGGTCATTTAATCTAAAATATGTCCTTAAAATCCTAAACTCTTTGTAATAACAATGGT GGAAGCACAAGAGGAATCATTCTCAATGACTATTTGAAATATTATTTTATTCTAAGTCAA AGAAGTATTTCTGATTTGGTAACTGTTTCAGCTAGAGCAAGCTGTGTTTTTGCTTTAAAA ATTGCATTTAGCCCTCTCTATGTGCAAATAGAGTTTCTTTCTTAAATTTTTAATTATTAT TCCTCAATGGAAGGCTGAAAGGAGATTTCATTGTATTATAGCCCTCATTGACTTTTCTCT CTAAATGATGACAAAAGCTTTTAAATTTAGTTATAAGGCAAAAAATACTTATGGACCTGT AAAGTGTGTGAAGAGGTGGGTGGGGGTAAAGACAATTAACATTTTCCCTTATGAAAAGGG CTGATTTGTGATATAATTTCTCTATTTATCCTTCATTTCCTGTGTGTCATTTTCAGCAAC ATTTCAACTTTAATATCTTGACTTTTGATCATTTTTTCCTCTTCACTTGAGAGTATTTCC GAGTTGTTATTTTTTGTTCCTGAGACTTTAGTCAAAGAATCTCTTCTACTTGTTCTTTTT ATTTTTCTACCAGTATACTGTGTGATCTACCTTTGTCTTTTCCAACGTCGGGCCCACATT GTATTTCAATACATCACCCTAATTGATAGAAAACTTGCGGGGATGTATTGTTCCGGCTAA TCCATTTTTCCTCTTAATAAAGAATCATGAAGAAACTTTATTTTCTTTTTTGACTCTGAC TGTTGAAAATGTTCCTAAAACAATAACCCACATTCCTGCCTTAGTAAGCACAGTGGATAT GATTGACTCCTGATGGCCGAAAACCTTGTAGTGTTTGAGAGCAACTCCTGCAGATATCAC TTCTTCCCAAATGTATGGTAAATTGAAATTTGAAAGAGGTGGAGGTAAACAGCTTCTGGC ATAATTGCGAGAGAGGCACAGGATCTCGTTACCCTATCCCCTCGCCCCTCATCAGAGAGA AACACCATAACCCCTATAAGAGCCATGCCCCCTCTCCCACCTGTGTGTGCAGGAGTTCAA CCTCCCTTCACTTGGAAGTGTGCAGAATTCTCTTCCTTTGCTGCTACTCCTTGAAAGCTA GCCCTCTGTGCCCTCACCTCTCGTACACATAAAGGGGGAAGGCATACCTTGGCAGTGCCT TTTAAGATAGTGAATGGCCAGGAAGTGGCTATATGAAACAAATCCTCATGATATCTAGAT TTCTTATGAGTTGATTTCTCATGAAAGTTCTGGTTCATAATGTTTCAGACTTGTGCCCTG TTGAGAATTGATGAGGAATCTAAAGGCCCCCTTCATATATAATACCACTGGTGGTCAGCC CCACTGAAGCCCCACTGGGACCTAAGGCCATGTCCCTGTTGAGCTCACAGCTGCAACGCT GTCACCTTGGGTCAGTTGTGCCTCTGGCTTCCTTGCGACATTCCTTAGAACTGGCTTGAA ACTGAAGCTCAGTGGGTGTCCACAAGGGCAATAGTCCGCTCCTTGCTGGAGAGAAGACAC TTTAACTTTATTTTTGGGTTATGCTGCTTACGTAAGTAAAATTAAATATAAGTAATTATT TTTTCCTGCTGGTGCTGACGTGTCACACCCACAGTAAAACTAGAATTGTCTTCACCAAAG GAATGGCTTGTGTGCGTGCAGGCATTATTCATGGTGAACACCACAGCGTTAACAATCCAC GTGTCACCATGATCAGATCCCGGAGCCACGCCTACTGGGGCATCGGTTTTTCCTAGCCTC ACTAGCTCTGATTTTACAATCCATCCCCTGGCAGAGAAATTTGGGGCTCTCCCTGGATGT CAGCAAATCACTGCTGGCTTGTAACTACCAGGTGGGAAGTGTTCATCCCTAATTGTTCCT AATTTTTGAAGTAATGGGAGTTTTCTTTTTTCTCTCCTACTGCTGAGCCTGTGAAGTACT TCCCCTACTCAGTTGGCTGAGTTAATCTGCTCTCAGAGAGGATGCAGGCTAATTTAGCAT AAAGGGAGTATGATTAGAAAGGTAAGTTTACAGGGCAAAGAAAGCACTGGAAGTCTTCCA AAGTAGAAAAGAACAGCTTTTTTGGATTATTCATTTTTTCCATAATAGAATATATACTCT AGCTTACTCTCAGTCACTCCAGTTTAGTTTCATGGCTATGTGAGAAATAATTATATTACA TTTTGCCCTAAATTTTTTTTTTTTATTGTGTTTAAGAACACTTAACAAGAAAGCTGTCCT CTTAGCAATTTTTTTTTTTTTTTCCAGACAGAATCTTGCCTGTCATCCAGGCTGGAATGC AGTGGTGTGATCTCAGCTCACTGCAACCTTCACCTCCTGGCTTCAAGTGATTCTCCTGCC TCAGCTTCCCAGTAGCTGGGATTACAGGCACCCACCATCACACCCGGCTAATTTTTGTAT TTTTAGTAGAGACAGGGTTTCACCATGTTGGCTAGGTTGGTCTCGAACTCCTGTCCTCAA GTGATCTGCCCGCCTCTGCCTCCCACATTGCTGGGATTACAGGTGTGAGCCACTTTGCCT GGCCTCTCTTAGCAAATTTTAAGTACAGGTTGAGCATCCCAAATCCCAAAATCCCAAATT TGAAGTTCTCTAAAATTCAAAACTTTCTGATTGCTGACATGATGCTCAAAGGAAATGTTC ATTGGAGCATTTCAGATTTCAAATTTTTGGACTTGGGATGCTTAACTGGTAAGTAAATAA TGCAGATATTCCAAAAATCTGAAAAAATCCAAAATCTGAAACACTTCTGGTCTCAAGCAT TTTGGATAAGGGATATTCAACCTGTATATAATACATTATTGTTGACTATTGGCACAGTGT TCTACAGATCTCTAGAGCTTATTAGAAGCTCTTAACTTAAACTTCATGCTTGTTGATTAA TAACTTCCATTTCCCTGGATATTATGCTATGGAGTTTTTGGCTCTACCTGCTACCAGCTT TCCCTTCCCAATATCAAGCAATATTTTTATTAAATTTGAAAACCTCAGTTACCAATGGAC TGCAAACAAACTCAGTGTATGAAGGAGCTAGTGGTTTTTAAAGCTCAAACCATATCAGAG GAATTTCATGTTTAGTAAATTTTAAAGTCTCCTTAGGATGTCTTAATGATGGGAGTAAAA ACAGAAAAAATTATGTGACAACCTTTGTATTTTATTTAGAAAAGGTTTTAATCAGGGAAG AGGGGTTGGTATTCAGGTTTTGAAGTTATTTGTGTGTGAAAACTTACTAGATATGTCTAA GAATTTTATTTTCCTTTTAAAAATTAAATGATGACTTTATTTCTTGGTGTTTCAGTTTTC CATACTTATAAAGCAAAGGAAATAATAAGAATCTCTTTGTAGCTCTGCTTTTATAAGGAT AACATAAAGTCTCAGATAATTGTGCCTACTACTCCTGAAGGAATTATATGTTGAGGCCTC TTTTTAAAAGTGTTAACTATTTTGAATAGTAGTGCTTTGCTAAATTTTGGTACTTAAAAC AGAGCCACAAAAATTAAGTGGTAATAGTAATATTTATATTTAAAATATGTCAGTTTATGA TGATATTAAGTTATTCAGTGGTCAGTTTATTCATCTATATACATGCTTAATATTATTTTT AAATGTTGTAGTGTTTTTGATCCATAGGATTTTGACTTTTCACATGCCTCTGTTTTATGA TCCTTGAAAAGAAAAGAAAAAATCAAGGCACAACAAACTTAAAAAGCAGGAATTTTGTTC TATATTGGTGGAGAGGAGCAAATAGACTGATGTGAGATGTTAGAAATATTTAGGTGTTGA CATCAATTGATAGATGTTGGTTATTTATCATACTGTAGTCTTAGTTAACAACATTAACGA TCCACGTGTCTGTGGTCAGATCCTGGAGCCTCGCCTGCTGGGGATCGGTTTTTCCTAGAC GCAATCATACTGTATTATAAATAAGAGGGAGAAAAGTGCTAAGGGGACCCCCTCCCTCCA ATTTGGGAAGATTGAGAAAAGCACATCTGTTTGTTTTCAATGGATGAAATATGCACATGG CAAATTTCAGAAGATTAAAAAAAATACTTAAAAGTATATTAGTATTTTTTTCTCCATTCC TTTAATCATCAAATTCCTCTCTATCTCTCCTCCCCCATGTTACGATAACGGATTTTTTCA GGTTATTTTGTCCTCTCTCCCACCACCCCAAGGTCATCTGTGCATATACATGCATATGTA TGTGTAACCTGTTTTGTTTTTAAAGCAAAATTGTAGCATTCTCTGCACTCTTTCCCTAGC TCCTTAGCTTTCAATTTTTGAAGATTGCTCCTTCTTAGTACTCATCCTTTCCAATATCCA GCTGGATGTACTAATATTATTTGGCTAGTATTCTCTTAGTGGACATTTCTGTTGGTTTTA GTGGATGTTAGGTTATGTGTATATTGAATTTCAAATGATATTACAGAATTGCTCTCTGTA AACTCTCCACTTTATATTTACAGCAATAATGAGTCATATTGCCTAGTTTTCTACATTCTT ACTAACATGATGTGGTCTTTTTGACCTTTGTTAATCTAATAAATGAAAAATTGTATTTTA ATGTAGTTTAAGTATTTCCTTTGAGGGAGGCTGAGCATAAATGAATACCTTTAACTATCA GGGTATTAGACTTGATCACCAACCACTCAGGTCCTTTTCTTTCCAGTTTATATTCTCTGT ATTGATGGTGTTATAAATTCTTATTAGCTTCAGTTACTATCCACTTAGATGTCTCAAGGC CACTTGTATTTCCTATTGTTGCTGTAATAAATTACCACAACCTTAGTGGCTTAAACCAAT ACAAGGTGATTATCTTAGAATTATAGAGGTCAGAAGTCCAAAACAGATCTCACTGGGCTA AAATTAGAAAGTTGACAGAGCTGCGTTCCTTCTAGAAGCCCTGGGGGAGGTTCATTTCCT TGTCTTTCTCCAGCTTTTGGAGGCCACCTGCATCCCTTGGCTTGTGGCTCCTTCCTCCAT TTTTAAAGCCAGCAGCAAAGCACCTGATTCTTCTGCCTTTCTCTTCCATCTTTTTAAGAA CTCTTGTGATTGCATTGAGCCTACTCAGAGAACGCAGGATAATCTTATTTTTAGGCCAGC TGCTTAGCAATCTTACTTCCATCTGCAACCTTTATTCTCCCTCAACATGTAACCTAACAT ATTCATAGACTCCAGGGATTATGATGGAGGGGCCGTTATTCTGCCTACCACATGGCTTAA ACTCCACATATCCAACACAGAATTCCATCACCCCACCCTAAACTTAGTCTTCCTCTAGTG TTCTGTGTCTTAATAAATGGTTCCTCTATCAGTTGAAGAAATAGATGTCTCCGAGTTGTT ATTGTTGATTCTATCTTTGTCTTCCTCGCTTTCTAGATATAATCTATCATGAACTTTTAT GGATTCTGCTGCCAAGGTAGATTTCTTAAAATTTTTTTTTATTTCAATAGGTTTTTGGGG AACCTTGGTGACATTTGGTTATATGGATAAATTCTTCAGTGGTGATTTCTGAGATCTTGG TGTACCCATCACCCAAGCAGTGTGCAGTCTTTTATCCCTCATCCCCCTCCCACCCTTCCC CTCGAGTCCCCAAAGTCCATTATAACATTCTTGTGCCTTTGCGTCCTCATAGCTTAGCTC CCACTTATAAGTGAGAACATAACGATGTTTGTTTTTTTCCATTCTTGAGTTACTTTACTT AGAACTGTGGTCTCTAATTCCATCTAGGTTGCTGCTAATGCCATTCTTTCTTCCTTTTTT ATGGCTGAGTAGTATTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTACATACACACACATACCACATTTTCTTTATCCACTCATTGATTGATGGGCAT TTGAGCTGATTCCATATTTTTGTAGTTGCAAATTGTGCTGTTATAAACATGTGTGTGAAA GGTCTTTTTCGTATTATATAATGACTTCTTTTCCTCTGGGTAGATGCCCAGTAGTGGGAT TGCTGGATCAAATTGTAGATCTACTTTTAGATCTTAAGGAATCTCCACACTGTTTTCTAC AGTGGTAGTACTAGTTTATACTCCCACCAACAGGATGGCCTTAAGTCATCCTCCTGCCTT GGCCTCCCAAAGCTCTGGAATTATAGGCATGAGCCACTGCACCTGGCCACTTTTTCTTCA TAGCTATTGTTATGGTTTGTAATTGTAACTGTTTTGTTGAGTAGTTAAGTATCTCTACTC TGAATGTAAACATGAAACACACACACACACACACACACACACACACACACACACACACAC AGTTTTTCAGTATTTTTTCTCACCTGCGCTATGTTGACATTCCCATTTCTGTGAGGTAGA ATGTAGCATATTTCTTAATGATATCTCAACCAGATTTTATAGCTTTCCTTTATCGTTTCA GCATTTAAGACTCAATCCTCTTTATTTTACACCTTCTGTCTTCAAATTGGGGAAGGGAAG AAATGACCTCTCCCATGAATTCTGTTGTCCTCCAAAGGTAACCATACCCTGTGTTCTGAG CCCCCTTTTTGGACTGACTGAGGTTTGGGTGAAATGATGGTTGGTGGAATTAGGGCCGGT TCTGGTGCCTCCTACTAAACTCTGGGAGGAGGTGACTTCGGCAATATCTGGTGCGCTCCT CTGACTGCTCTGTGAATGTATATTGTGATGTGCTTAGGTCTGGGCCTTTGCTATAATTTC AGGATATGAGGATCATGGCTGGGATGCTATTACATAATTTGTTTTTGTGATTGTCAGAGA ATTTTCCTTTTCCTCATTACACAGAAAGGTTCGTGAGTACAATAATGTATATCTATCTTT TCCCTTCATTTGTTTCTCAGTGGAGTGTGACTAGCTGTTCCAGTTTGTCCAACACTGAAG GGGTTTCCAAAGACATGGGACTTTTAATGCTGAAACTAGGAAACACCTGGGTAAATTGGG ATGAGTTCATTAGTGTATTGCAGTGCCTTTTTTTTTTTTCTTAGCACAATGACAGTGACT GACAAAATGGTTATACAACATTTTTTGAAAAAACATGAGTGCGGAAGAGTTTTACAAAGA CTAACCAGTCAAGTTATAAATGATTATAACCAATATTAATGATTGTGTATTTTTGTTTTA CTTCATTAATAAAAATTTAGCATAAATAAAATTAGTCATTGTGCAGCCTCAGCTGTTTAG TGATTAATTTCCTTCACTTTAGGTTTCTAATTTACAATTATACCTGGCAAGTGGTAGGGA GTTGTACAGGTAGAGTATGAAAAGCAGAATTCAGTTGACTTAATGCTTTGTGAACCGGAT CAATAATTTATTTGTAGTGTTGAATAAGACTAACATATTTAGGTAGCATTTCAGTATTGC TATTTTTTTCCCTTTTATTTTGAAAAGTTGTTTACTTTGGCAAGCAAGGCTTAGGTAGTC TGTGTGGTCTGTTCCTGTCCAACTGTGACACAAATCTTTGTGTGGCCATTGTCAAGTCAC TTTTAAAAATCAGGTATGATTCAGTTGGTTGGTGCTGGTCACTTTTGAACAGTTCCTAAG GACGGGTGCTATCATTAGAAGATCCAATGATGAATGGGCCTCAACTCACAGTAAGTTTAT ACTTAAGGAAGTGATTTATACTATTTTCTGAATATGGTGATACAAATTAGGGTAAAAAAG ATCAATGCTTATATTTTGATAAATTGAGAACTATTTTCTTTCTAGTTTCCCCTCCTATTT TTCTTTTTCCGTGATTGCAGTCTTCGGCATATGTGTGTCATACACCTCACAGGGGACCAG TGGATCTCATTGTGCATTCTCCCTCCTCCCCCAGAAAAACCTTATACTTCCCCTTTTCTT TAATAAGAAAGCACTGTGGTGAAGTGTGCTTTATGTTTTTTAGTGGAGTAATCAGAAAAT GGATTATCTCAGATATGGACTTGTGAATTTGGTATAATTTCTTAATAATTATTAAGTTCA TTTAATTGTAACAACTTCATATATTGTAGTGTAGGTATTATTCTCCCAATGTGTGACAGA TGATGACGTACCTTCAGAGAGGTGGCCAAGGTAGATTGTGGTTGTATGTTAGCAGAAGTA GCACTTTTATTCTGAAAGGTAGGGGCTGGTATTCTACACATAAAATACACAGTATGTTAG TAGCCACATGAGTAGCTAATACTCATTTTAAGTGTTTTCCTCCAGCTAAACTTTATCAAT TAAGAGACACTCTCACCTTATTATTTACAATTTTCTACACTGGAAAGTGATAGTTTATAC ATGCCAGTAGTAGAAAAAAATGTAAGCATTTGTAGTTTCCTTCGTGAGGACTAAATCCAT TCTAAGCAGAATCCTAAAAATGTGACTTCCTTCTTTGATTCTTTTGTTTCTTAACCCATT TATTCATCCATCCATCCATCCATCCAGTATTATTATTATATGTCTGCTACATTTCAGATA TTGTCAAAGATTGAGGGATTGGTGGGTCAAAGAAATGAGGTGATTAAGACCCAATCCCTG TTTTATATGAAGTCAAGCTCTACAAGTTGCATGTTCTTGGTAATCTCTTACTGACTACCA ATTGACTTTCTAAATATTTGCTGAGTACTTTCTCCGTGTCAGGCACTGCTGTTAACAGTG GAATACAAAGTGAATAAGATTCATGCAGAGTACTTCCTGTAATACCAGCTACTCGGGTGG CTGAGGCACGAGAATCACTTGAACCGGGGTTGGGGGCGGGGGGGCGCGGAGGTTGCAGTG AGCGGAGATTGTGCCACTACCCTCCAGCCTGGGCAACAGAGAGAGACTCACTCTCTCTCA AAAAAAAAAAAAACAAAAAAAAACCTCATACAGAGTTCCTATGTTCACATATACATACCC ACACACACTATATCCACAGACATGCATACTACAGACTACATACATATACATGCAAATGAA TATATGTATACATAGGCAGAAAGCATGCAGTTACATTCCCATAAACATATGGATATCATC TGGAAATATGTATGTTTATGTGTCTGCAAGTGCGTGTAAATCAATGAGCTCATTGAACTG AGGGTGATTTCAGGAATCAGGCATCAACCAATATTATGAACTTGTAGCCAGGTTCTTCTC TGGCCTCGTTTGCCCATTTGTTCTCTATGGGAGAGACACAGGGATTAGTTAGCCTGCTGA CAGCTATGGGTTTTGTGTGTCCTGTGCTGAGGATAAGAATGTTCTTTACTGTGGGTGGCC TAATTAAAGCCTCATGAATATTGAGTGCCACGTATGTCTCATATATAATTTGTGCAGCAT GAATATTTAGTGCCTCAGGTGCCTCATGCATATTTAGTGCCTCATGAATTTTAGAAGCTT CTTGGTCCTTCCGTCTTCTTCTGTGTTCATGCATACGTGTTCTGCTTGCTTTACCTAATA GGTTTCATTACTTATCTATGCTTAACACATTTTATGAGCTTCATCTATCCCATGTATTTT CCTGTCTTATTGATCATAGTTTCTTGTCCTATTAAGCAGAATTGAATTTTCTCCAGCACT ATAGCAAATTTACATTACATCTGTCCATTTGGAAAGCCTATGGCCCAGATGCTTTATGGA AAAGAAAGCTATTTTTAATATTCAGAATTTCAAGTCAGTACATACACTTACAGATATTTT CCAGTGTAGGACTTTTCGTAAAATCTTTAGCATAATAAAGCTCAAAATTGATTTAACAAT CTAGAAAAAGTATTCTTGAGGAATTCATTCATGCTAGTTTATGGTTTTGCTTAAAGCTTG TGGTTGGAGATGGTAAGGAAGGAGAAGGTAATATTCCTTACTGGCTTGGGGGTTTTGAAC TTTAACTGGCCAGCTTTAGCCCTCTATGTTGTAAACATTTTTGATGTAGTTACAATTCAA AGTTATGGCATATGGAAATGTTCTATTGTAGGATAAAGTGGCGGAGTAGTATAAATAGGG TTTGGCTGGCTAAAAAGCTCCATTTATTCTGACTTTGAGTCAGTTACCCATTAAGCTTAT GGGTTTCGAGTAACCTAGGGGTGTGTTTAAGGTTAGTAGTAATTGACAGGGTTGTTTGTA TTTTCTGTGTATTGTGGGAGGAAGTTCATTCCATTTCATGATTAATGGTCAGGAAGGGAC TTCTAGGATTTGGTGTTTCATCTTCCACCATTGAAGAGGATCTCATTTAGATTGTTGAAG AAGATATCTTTGAACAGACACATCAGCCATCCTGCATATATTTAGGGAAGTGGTACACAA AGTGGTTCATGTACAGAAATGCTTTTCCATTGTGATTGACACCAAAATAAACTTGCTGAA ATTGAAGAATCATAAAAAATATATGCTCTATGTATCTTATTCCCTTCAAATATTAGTATG TATTTATTCATGACCCCTGCCCCTTTTATTTACAGGGACAAGGCCTTTTCTGAATATGAG AGGCTGACTAGAAATATGTATTTTGTGATTATTTATTTGACAAACACATTTGGGGACAAA CACAGTTGAACCTTGGTAAGTAGATGATACATCTGGTGGTGGGAGCAGAGGTGCTGGCGG GTGCATGGGTGTATCTTGTTAAACCGAGTATTTGGGGTCCTCATATGCATCAGTCACTTT GTTTTACAGGAAGGGAGAGTGGCAGTGATGTGAAGGTTGAAACTGTGTTAGAGCTGCTTC TGCATTTCATACTTTCATTCTTTTTTGTCTACCTTGAATTCCAGCTTAGATCTCTACTGC ATGCCAGTGATGGAGAGGGAAGAAAGGCATTTCTTGTATTGGAGGCTCTTGTTTGTGGCA TTCTGGAGCCATTTAAACAGGCAGGGGCTGGCAGCCTGAGGACTGTTCTCTAGTGGATCC AGCTCCAGAGGGTGCTGTGCACACGATGTCACAGGTACCATGTGGCTTTAAGGTAGTAAA AACGCATCCCTATGTTGCTTTGAGTATACAAAAATAGTTAACATCCAATATCGAGTGCCA GGCCCCAGGCTAAGCACACTGCGTGAAGGAGCACATTTGATTTTCATGGCATTGGATGGC ATAGCAGACTTGGCCACACCTCTTGCGACTCACCATCCTGTGTCAGGATGGCTACTGCAA GCACCAGGTAGAGTGACCAGCTGTCTCCCTTTGCCCTGATCTCAGGGTTGTCCAGAGAGT CTGAGTTTTTAGTGCTAAAAGGAGGGTGAGTTGGTCACCCTAGTCCCTGTGACTGCTGTC CAAGGACACCGGCAGCCAAGGAACCTCTCTCACAGTGGATGCTGCCCTCTACCGGTGACA CCGGTGACGGTGATTGGTGGGTGAATACCATCTCTGCAGTCTCCGAGAGTTCCCCTGCAG AATTCGTCCTGTGGCCCACAGAGAGAACCCACTCACACGCTCATCCATGTAGGATTCCCT CTTTGCTCTTTTGCATTTCACTTTCTCACCTCCCTACCAGCGCCTCCGGGGATCACCTTC TGCATAAATGACTTTCACTCAGGTACTTGTCACAGGGTCAGCTTCTGGGGGAATCCAGTC TAAAACACATGGGTAGAACTGCTTTACTACCATTTCACATAAGAGGAAACTGAGGTGTGG GGAGGTTAAATAATTTTGCTCAAAATTGTACAGCTGGCACACAGAGCTAATAATTCTTAG TTATTAAGTTATACAGCTTTACTTTTTTTTTTTTTAGTTTTTAATTTTTTGAGACAAGAT CTCACTTTGTCACTCAAGCTGGAGTGCAGTGGTGCAGTCATGGCTCACTGCAACCTTGAA TGCCTGGGGTCAAGCTATTCTCTTGCCCCAGCCTCCCAAGTAGCAGGGACTAGACGTGCA TGCCACCATGCCTGCTGATTTTGTTCTTTAATTTTTGGTAGAGACAAGGTCTCGCTATGT TGTCCAGGCCAGTCTTGAACTCCTGGTCTCAAGTGATCTTCATGCCTCGGCTCCCAAAAC AATAGGATTACAGGCATGAGCCACTGTGCCCAGCCATTACAAATTTTTTAAATTATTATT ATTATTTTTTTTAGTGATGGGGTCTCATTATGTAGCCCAGGTTGGAGTGCAGTGGCTATT CATAGGCATGGTCATAGTGCACTGCAGCCTTGAACTCGTGGCCTCAAGCGATCGTCCTGC CTCAGCCTCCCGAGTAGCTAGGACCATATATGCACACCCCTTTGCCTGGCTTAAGTTATA CAGCTTTTGTTCCTATCCTCACCCATGTGTATTTATTTCCAGGAAATCTACAATTTCATT TATTCATATGGGATTAACAATAAGCTATCATCAGTCCAGTGGGGTTATGAATGGTATGTT ATTATTCTATCTCTACTAAATTCATTGAGCATGGAGCAGAAGTCTTGATTTTAATGGACT TAGGGGAGTTTGATGGGACTGTTTTTATGAAGGAGAAATTTGTCTTTTATACATAAGTTG CCAAAACCAGTGCTGTTGCTGACTAAGGACTAAGTGCCTATCCCTTGCCTAGCTATGCGC AGTCTGGCCTTGACTGGAAGCAGGAATCGTGACATCTCTGACCAGATTGGATGTAAACTG CCTGCTTGTGCTAAGGAGTTGTGTCTGCTGGTTCTTGGCTCCCATCCTAGAGTTCTCTAT GAAATGACTCATTATAAGGAAGTCTATTAAAAACAAATCTCTCCCCATTTTAGAGTATCT CTTAAAATTTCTTCTTAATAAGAGAATTTTGGTGCTTTCAGTTCCAGTTAGTGCCAAGAA ATTTGAAGTGTGTATTGAAGAAGGCTATGATAATTACAGTACTTGAATTTCTTGTAAAGA TAGATGCTTTGGGAAGTGAGTGTATTTCCCTTTTATTTGAAAGACAGAAGCTTGGAAATT CTACCAGACTTAAAAAAAAATTTTTCTCTCACTGCAAATCCACAGCCTAATGGAAAGTGC TCCAAGTTTCTCTAGTGAAAGTGGCTTCACTTACCTCAGCATTTAAGATCCTTCCCCATT GTTGTAGTTTTATAGGTATTTTAGATTATCTATTTAAAAAGGCAGCTGCCTGTCAAATGA TCCACATAAATAAAATAAGATTGTGCAGAAGTGTAGAATATAACCACATGCCAATCCTTA GGAAACAGTGGGAAATGTTTTACTTTAAAAATGTAGGGTTTTGCTTTTACAAAACTGATC TTTGACCACCGGTTCTCTCAGGCTTTGCCTTTTCTAGTTCAATGATCTTTTCTACTAGTT CCCCCCTCCCTTCCCTCAAAGGCCTGAATAGACACTTCCCAGTTTGGGAAATAGACCTTC ATTAGTTACACCTGGCTCAGCATTTTTTTTTCTTTTCTGCACATCTGCTTAGCATCATGT ATTTGAAGGTGCCACATACATGTTTGCTAACGTTGCTTTAGATGCTGTTGAGTCATAAGA AGATAAGCAGTGCTAGGGAGGATTCAGTCCAGCTTGATATTCTTCTCCACAAGTGTGACT TGGGTAGGGAAAGGGGGACACTTTCTTTGGTCAAGACGGAAAAACAGATTCATGTTACCT GTCATTAGCATAGTAAAAACTATGGGAAATGTCTTAGTCCATTCCGGCTGCTATAACAAA ATACCATCAACTGGGTGGTCTATAATGAACAAAAATTCCCACTTCTGGAGGCTGGGAAGT CAAAGATCAAGCGTCTGGCCTTCAAAGATGTGCCTTCTCTGTAACCTCACATGATGGAAG GGGCAAAGGACCTCTCTAGGTTCTCTTTTATAAGGGCACTAATCCCACTCTTGAATGCTT CCTCACATGACCTAACCACCTCCTGAAGACCCCACCTATTGATAAGTATCATTACCTTGG GAGTTAGGTTTTCAACATATGAATTTTGGGAGATACAGGCATTCAGACCACAGTGGAAAA TTAAGCTTAACTGATGGGGAGATTTAGGAGATGCAGTGAGAGAGCTTTGTTGTGCTGTGT GCTCTGTTCTCTCAATATTATGATTTTAGGAAGGCCATTGCCTTCTCAAGAGTTTAGGTA TGTGCTGCAAGCACTCAGCTTTTTATAATTTACATCCTTCCTCTACGGATGGTTGAATGA ATGAATTGCTCTGAATTCTTGTACCTATTTCTATTTCTGGCCTGTGCAATTGAGTTTAAT GTTCGCTAACCACATATAAAGTTGTGCTTAGCAATGTTTCTCAAGTGGTGTTGTTTATTG TTTTTCTAGATTATATAGAGTAATACAGAATATACTTTCCAGAATATGACACATCTTTGT ATTCTCTCCATACCTTTTATAATTTTATAAATGTGATTTTATAATGTTTTTAACTTATCC TTGCTGCAATGAAAATTTCCACAACAAAGTTTATTAGAGGAAAAACATACATTTTACTTA CTGTATTAATTACCCTTATTTGAAGACGGTTTTTTGTTATGTGTTGTGATGAGAAATAAC AAGCAGTATTCCCTGTATAGCCGAGTATTACTTTTGGCTAAAGTTAGGATAATGTTCTTT GCCCTATTTTGTCATTGCCCATTTTTTCTTCTTGTTAGGGAGGCAGAGGTGGTGGTGGAG ACAACTGGGAACAGCTAGAACTGAGTTAATATCTTTAGAGAATAGTCTGCTATGACATTG TTTTTGTTTCCCTCTATAAACCCTTCAAATAATTTTTAAGAAATTCCTCTGGGCCAGTCG CAATGGCTCAGACCTGTATTCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGT CAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAA AATTAGATGGGCGTGGTTGGTGGCGGGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGG CAGGAGAATGGCGTAAACCCAGGAGGCGGAGGTAGCAGTGAGCCAAGATCATGCTACTGC ACGCCAGCCTGGGTGACAGAGTGAGACTCCGTGTGAAAAAAAAAAAAAATAGCTGGGCCT GTTGGCGTGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAAGCAGAAGAATTGCTTGAAC CCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCACCACTGCACTCAAGCCTGGCCACAG AGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAATCCTCTGCATTGAGAG CCAAGTGTTCGGGCTCGGTGGGTCTTACCCTGACAGAGCCCAGCACACTAAGATCCACTG GCTTGAAATTCTCGCTGCCAGCACAACAGCAGTCTGAGATTGACTGGGACGTTCGAGCTT GGTGTGGGGAGGGGTGTCCTCAGCAATGGTCCACCATTGCCTATGCTTGAGTAGACTGTT TTACACTCACAGTGTAAAAAAAGCCACTGGGAAGTTCGAACTGGGTGGAGCCCACTGCAG CTCAGCAAGGCTGCTGTGGCCACACTGCCAGATTTCCTTTCTCTGGGCAGGGCATCTCTG AAAAAAAGGAAGCAGCCCAGGTCAGGAACTTACAGATAAAACCCCCATCTCCCTGGAACA GAGCACCTAGGGAAGTGGGTGGCTGTGGGCACAGCTTCAGCAGAATTAATGTCCCTGCCT GACAGTTCTGAAGAGAGCAGTGGACCTCCCAGCACAGTGTTCAAGCTCTGCTAAGGGTCA GACTGTTTCCTCAAGTGGGCCCCTGACCCCCTTGTATCCTGACTGGGAGACACCTCCCAG TAGGGGCCGACAGACACCTTATATAGGAGAGCTCTGGTTGGCATCTGGCAGGTGCCCCTC TGGGACGAAGCTTCCAGAGGAAAGATCAAGCAGCAATCTTTGCTGTTCTGCAGCCTCCCC TGGTAATACCCAGGCAAACAGGGTCGGGAGTGGACCTCCAGAAAACTCCAGCAGACTGGC AGCAGAGGGGTCTGACTGTCAGAAGGAAAACTAACAAACGGAAAGAAATAGCACATCCAC TCAAAGACCCCATCCGAAGGTCACCAACACCAAACACCAAAGGTAGATAAATCCACAAAG ATGGGTAGAAACCAGCGCAAAAATGCTAAAAATTCCAAAAACCAGAACGCCTCTTCTCCT CCAAAGGATCACAACTCCTTGCCAGCAAGGGAACAAAACTGGACGGAGAATGAGTTTGAC AAATTGACAGACGTAGGCTTCAGAAGGTGGGTAGTAACAGACTCCTCCAAGCTAAAGGAG CATGTTCTAACCCAATGCAGGGAAGCTAAGAACCTTTAAAAAAGGTGAGACGAATTGCTA ACTAGAATAACCAGGGTAGAGAAGAACATAAATGACCTGCTGGAGCTGAAAAACACAGCA CAAGAACTTCATGAAGCATACACAAGTATCAGTAGCCGAATCCATCAAGCAGAAGAAAGG ATATCAGTGATTGAAGATCAACTTAATGAAATAAAAAGAGGAGACAAGATTAGAGAAAAA AGGATAAAAAGGAATGAACAAATCCTCCAGGAAGTACAGGACTGTGTGAAAAGACTAAAT CTACATTTGATTGGTGTACCTGAAAGTGACGAGGAGAATGGAACCAAGTTGGAAAGCACT TTTCAGGATATTATCCAGGAGAACTTCCCCAACCTAGTAAGACAGGTCGACATTCAAATT CAGGAAATACAGAGAACACCATAAAGATACTCCTTGAGAAGAGCAACCCTAAGACACATA ATTTTGAGATTCTCCAAGTTGAAATGAGGGAAAAAATATTAAGGGCAGCCAGAGAGAAAG GTCAGGCTACCAACAAAGGGAAGCCCATCAGACTAACAGCGGATCTCTCCGTAGAAACCC TACAAGCCAGAAGAGGGTAGGGGCCAATATTCAACATTCTTAAAGAAAAGAATTTTCAAC CCAAAATTTCATATCCAGCCAAACTAAGCCTCATAAGTGAAGGAGAAATAAAATCCTTTA TAAACAAGCAAATGCTGAGAGATTTTGTCACCACTAGGCCTGCCTTACAAGAACTCCTGA AGGAAGCACTAAAAATGGAAAGGAACAACTGGTACCAGCCACTGCAAAAACATATGAAAT TGTAAAGACCATCGACAACATAAAGAAACTGCATCAACTAATGAGCAAAACAACCAGCTA GCATCATAATGACAGGATCAAATTCACACATAACAATATTAACCTAAATGTAGGCTAAAT GCCCCAATAAAAAGATGCAGACTGGCAAATTGGATAAAGAGTCAGACCCATCAGTGTGCT GTATTCAGGAGACCCACCTCAGGTACAAAGACACATATAGGCTCAAAATAAAGGGATGGG GGAATATTTACCAAGCAAATGGAAAGCAGAAAAAGCAGGAGTTGCAATCGTAGGCTCTGA TAAAACAGACTTTAAACCAACAAAGATCAAAACAAAGAAGGCCATTACATAATGGTATAG GGATCAATGCAGCAAGAAGAGCTAACTATCCTAAATATATGTGCATCCAACACAGGAATA CCCAGATTCATAAAGCAAGTTCTTAGAGACCTGCAAAGAGACTTAGACTCCCACACAATA ATAGTGGGAGATTTTAACACCCTACTGTCAATATTAGACAGATCAACGAGACAGAAAATT AACAAGGATATTCAGGACTTGAACTTAGCTCTGGACCAAGTGGACCTAATAGACATCTAC AGAACTCTCCACTGCAGATCAACAGAATATACATTCTTCTCAGCACCACATCACACTTAT TCTAAAATTGACCATGTAATTGGAAGTAAAACACTCCTCAGCAAATGCAAAAGAATGGAA ATCATAACGAACAGTCTCTCAGACCACAGTGCAATCAAATTAGAACTCAGGATTAAAAAA CTCACTCAAAACCACACAACTACATGGAAACTGAACAACTTGCTCCTAAATGACTGCTGG GTAAATAACGAAATTAGGCAGAAATAAAGATGTTCTTTGAAACCAATGAGAATGAAGACG CAACATACCAGAATCTCTGGGACACATTTAAAGCAGTGTGTAGAGGGAAATTTTATAGCA CTATGGCCACAGGAGAAAGCAGGAAAGAGCTAAAATTGACACCCTAATGTCAAAATTAAA AGAACTAGAGAAGCAACAGCAAACAAATTCAAAATTTAGCAGAAGACAAGAAATAACTAA GATCAGAGCAAAACTGAAGGATATAGAGACATGAAAAACTCTTTAAAAAATCAGTGAATC CAGGAGCTGATTTTTTGAAAAGATCAACAAAATAGATAGACTGCTAGCCAGACTAATAAG AAAGGAGAGAAGACTCAATTAGACACAATAAAAAATGATATAGGGGATATCACCCCTGAT CCCACAGAAATACAAACTACTATCAGAGAATAGTATAAACACCTCTGTGGAAATAAACTA GAAAATCTAGAAGAAATGGACAAATTCTTGGACACATACACCCTCCCAAGGCTAAACCAG GAAGAAGTTGAATCCCTGAATAAACCAATAATAAGTTCCGCTCAACTTGTTTGAGGGATC AAGTTGGCTTTGCCCCTGGGATGCAAGGCTGGTTCAACATACACGAATCAATAAATGTAA TCCATCACATAAGCAAAACCAATCACAAAAACCATGTGATTACCTCAATAGATGCAGAAA AGGCCTTCAACAAATTCAGCACCCCTTCATGCTAAAAACTCTGAATAAACTGAGTACCCA TGGAATGTATCTCAAAATAATAAGAGCTATTTATGACAAACCCACAGCCAATATCATAGT AAATGGGCAAAACTGGAAGCATTCCCTTTGAAAACCAGCACAAGACAAGGATGCCCTCTC TCACCACTCCTATTCAACATAGTATTGGAAGTTCTGGCCAGGGCAATCAGGCAAGAGAAA TAAAGCGTATTCAAATAGGAAGAGAGGAAGTCAAATTGTCTCTGTTTGCAGATGACATGA TTGTGTATTTAGAAAACCCCATCATCTCAGCCCCAAATCTCCTTAAGCCGATAAGCAACT TCAGCAAAGTCTCAGGATACAAAATCAATGTGCAAAAATCACAAGCATTCCTATACACCA GTAACAGACAGAGAGCCAAATCATGATTGAACTCCCATTCACAATTGCTACTAAGAGAGT AAAATACCTAGGAATACAACTTACAGAGAATGTGAAGGACCTCTTCAAGGAGAACTATAA ACCACTGCTCAAGGAAATAGGAGAGGACACAAACAAATGGAAAAACATTCCATGCTCATG GATAGGAAGAATCAATATTGTGAAAATGGCCGTACTGCCCAAAGTAATTTATACATTCAA TGCTATCCCCATCAAGCTACCACTGACTTTCCATACAAAATTGGAAAAATCTACATAAAA CTATTGGGGGAACCCACCCCCAATATTTCAATGTAAGTTCTTTCTATTTTCTATAAGTGT CAGCTGGCTGAGAAATAAAGACAGTACAAAGAGAGCAATTTTACAGCTGGGCCGCCAGGG GTGACATCACATATCAGTAGGACATCACATGTCAGGTAGGAATCACCATGATTCCTGCCT GAGTCTCAGACCAGCAAGTTTTTATTAAGGGTTTCAAAAGGGGAGGGGGTGTAAGAACAG GGAGTAGGTACAAAGATCACATGCTTCAAAAGGCAAAAAGCACAACTACTAGTAAGGGTC TAACACAGATCACATGCTTCTGAGGGAACAGGACAAAGGGCAAAAGCAGAACTACTGATA AGGGTCCAACAAAGATCACAAGGCAAAGAGCAAAAGCAGAACTACTGATAAGGGTCTGTG TTCAGTGGTGCACATATTGTCTTGATAAACATCTTAAACAGCAGAAAACAGAGTTTGAGA GCAGAGAACCAGTGTGACCACAAATTTACCAGGGCAGAGTTTCCCAACCCTAGTAAGCCT GAGGGTACTGCAGGAGACCAGGGGGTATCTCAGTCCTTATCTCAACCACATAAGACAGAC ATTCCCAAAGCAGCCGATTATTGACCTCCCCCCAGGAATGCATTCCTTTCCCAGGGTATT AATATTAATATTCCTTGCTAGGAAAAGAATTTAGCGATACCTCTCCTACTTGCACATCCG TTTATAGGCTCTCTGCAAGAAGAAAAATATGGCTCTTTTTGCCCAACCCCGCAGGCAGTC AGACCTTATGGTTGTCTTCCCTTGTTCCCTAACAATCGCTGTTATTCTGTTCTTTTTCAA GGTGCACTGATTTCATATTGTTCAAACACACATGTTTTACAATCAATTTGTACAGGTAAC ACAGTTATCACAGTGGTCCTGAAGTGACATACATCCTCAGCATATGAAGATAACAGGATT AAGAGATTAAAGACAGCCATAAGAATTACAAAAGTCTTATTTGGGAACTGATAAATGTCC ATGAAATCTTCACAATTTATGTTCCTCTGCTGCAGCTCCAGCTGGTCCCTCTATTCAGGG TCCCTGACTTCTCACAACATAAAACTTCATATGGAACCAAAAAAGAGCCTGCATAGCCAA GACAGTCCTGGGCAAGAAGAACAAATCTGGAGGCATCACGCTACCTGATTTCAAACTATA CCACAAAACGACAGTAACTGAAACAGCATGTTACTGGTACCAAAACAGAGATATGGACCA ATGGAACAGAACAGAGGCCTCAGAAATAATACTGCACATCTACAACCATCTGATCTTTGA CAAACCTAACACAAACAAGCAATGGGGAAAAGATTCCCTATTTAATAAATGTTGTTGGGA AAACTGGCTAGCCATATGCAGAAAACTGAAACTGGACCCCTTCTTTACACCTATACAAAA ATCAACTCAAGCTGGGTCAGAGACTTAACTGTAAGACCTAGGACCATAAAAATCCTAGAA GAAAACCTGGGCAATACCATTCAGGACATAGGCATGGGCAAAGACTTCATGACTAAAACA CCAAAAGCGATGGCAACAAAAGCCAGAATTTACAAATGGGATCTAATTAAATTAAAGAGC TTCTGCACAGCAAAAGAAACTATCATCAGAGTGAACAGGCAACCTACAGAATGGGAGAAA ATTTTTACACTCTATGCATTGACAAAGGGCTAATACTCAGAATCTACAAAGAGCTTAAAC AAATTTACAAGAAAAAAACAACCCCATAAAAAAATGGGCAAAAGATATGAACAGACACTT CTCAAAATAAGACATTTATGCGGCCAACAGACATATGAAAAAATGCTCATCATTACTGGT CATTAGAGAAATGCAAATCAAAACCATAATGAGATACCATCTCACACCAGTTAGAATGGC GATCGTTAAAAAGTCAGGCAACAACAGATGCTGGAGAGGATGTGGAGAAATAACCCTTTT ACACTGTTGGTGGACGTGTAAATTAGTTCAACCATTGTGGAAGACAGTGTAGCAATTCCT CAAGGATATAGAACCAGAAATACCATCTGGCCCAACAATCCCATTACTGGGTATATACCC AGAGGATTATAAATCATTCTACTATAAAGACACATGCACACATATGTTTATTGTGGCACT GTTCACAATAGCAAAAACTTGGAACCAACCCAAATGTACCTCAATAATAGACTGGATAAA GAAAATGTGGCACATATACACCATGGAATACTAGGCAGCCCTAAATAGGGACGAGTTCAT TTCCTTTGCCAGGACGTGGATGAAGCTGGAAACCATCATTCTCAACAAACTATCACAAGA ACAGAAAACTAAACACTGCATGTTCTCACTCATAAGTGGGAGTTGGACAGTGAGAACACA TGGACATAGGGAGGGGAACATCACACACTGCGGCTTGTCAGTGGGTGAAGGGCTAGAGGA GGGATAACATTAGGAGAAATACCTAATGTAGGTGATGGGTTGTTGGGTGCAGCAAACCAC CATGGCATGTGTATACCTATGTAACAAAACTGCACGTTCTGCACATGTACCCCAGAACTT AAAGCATATTAATAAAAAAAATTCCTCTGAATTTTCTTTTACTTGTCCTCTTTCTCTCTC CTTAATCCTACCCAGAAAGGGGTTGGGGACAGTACCAGATCAGTGTGGATTACCTGTTCA AGGCACATCTCTATGAAAAAATTCTGAGACCAGTTTTTGTCCTTTTTAAGAGTGGGAGGG TGATGTAAGAGAGAGACTTTTTTCTTATGGGATCTGATTGTCCCCCAAACATCACTCCTG CTCTGACTAACATGATTTTAATTGTCTTTCACAAAATCTAACTAAAGAGGGTGTGTGTGT GTGTGTGTGTGTGTGTCAGTGGGAACATCTTGTGTTTGTATTCTGTGATTCATTACTTTT TGGAAGTTATTTGGACAAAGATTGTCAAGAATTGCTTCAAAATGCATCCCACTGATGCTC ACGTTCTCGTTTCCTAATTGCTGATGGGGAAGCTTTTGCTCCTCCTGTTGTAGTCACTGC TTCTGCCCATGTGTGTTGGGGGCTCCTCACAGTTCATACAGCAGCACTGTTTTGAGACAT CAGCTCCCAGCCCTTACTGTTACAACATGCATGTCACATAGCACCCCGTTTTTCAAAATC ATTTTTGTTGGCTTGTGATTATCCTCATAAAAGGTGCTTAATTGGAAGCCTCACAGCTGT AGCTTTCTGTTTATAGCCACTGAGTAGGTACAGTTAAGCTGACTGCATTTTACGTGTTGT GAGCCACGGCCCGGGAATGGAGAGATTCAGGCTGTCTCTAAGACAGAGCTATGGGGAGAA GCTGTACACGACTTACTGGAAGGTAAGCATTCAGGCTTAGACAGTTGAAGAACTTGGTCA AGATGTGCTGTTTTGTACATTCATTTTGACTTTGTTAAACTTAAAATATCCTTTGGAAAT GAAACTTTTCTTTACTAGATTTAGTTAGATATATGAGTGAATACAAATTCATATAATATA GTTGACTCTTGAATACTATGAGTTTGAACTGTATGGGTCCACTTATGTGTGGATTTTCTT GCACCTATGCCACCCCTGAGACCTCAAGACCAACTCTCTTCTTCTGCCTCCTTCTCAGCC TGCTCAGTGTGCAGGTAATGAGGATGAAGAACTTTATGATGATCCACTTCCACTTAATGA ATAGTAAATGTGATTTTCTAATAATATTTTCTCTAGCTTACTGTATTTTAATAATACATT ATATAATACATGTAACATAGAAAATATGTTTTAATCAGCTGTTTATGCTATCTGTAAGGC TTCCAGTCAGTAGTAGGGTACTAGTAGCTAAGTTTTAGGGGAGTGAAAAGTTGTACGTGG ATTTTCTACTTCCAAAGGTAGTTGCTGACCCAACCCCTGTGTTGTTTAAGGGTCAACTAG AATCCTTTTTTTCTCACAAATGGATAATTTAAAATAGAATTAGACTTGATAAGAACACTT CACTAGTTTTTACTTGGGTATTTATGTGTGTACATACTTTTTAGGCAGTCATTTTAAAAC TTATATATATATATATATATATATATATATATCTCCCAATAAAATTTGGAAAATAAAAAA AATTTAATATAATCATACTCTTCCCTGGCATACACATTTTGATCTTGTGATGAATGTTCC TAGTTTTTATGTGTTTATTTAAAGAATAATAGTTACAATCATGTTTCACATGTAATTTTA TAATCCACTTAAAAATCATGCCTTATTTTCTTTTTTATGCAGTTTATCATAATCATTTTT CCTTATTGCTTCAAAGAGTTTTGCAAATCCAAATCATCTTTTCAAATGACCTTAAAATGT TTGAAAAAGTGTCTATATCTAAATTTTCTTAATTCCCATATTGGTTTTTCCTTGTTTTTG CTTATTATGTGTATTACTAAGATGACATGTTTGTGGCAGTAGTTTTTCTTCTTTCTCTTC TTACTTGGATTATATTTTTAAGACCTAGACTCTTAGAAATAGAATTACTGGATCAAGTAC ATGGAAACTATAGTTATTCTTTATATAAACCAAATTATTCTTCAAAATGGTTGTGTGAAT TTACACTTCCGCCATTGTACAAACACTACATCATTACTAGTGCTTATGATATTACTGAAT CTCAGGGTTATAATTATATAAATTATACAATCTTCAACTGAGGTAAAATCTTTTAAGTTA CCTGGGAAAATACACCATTTAAAAAAGGATGGATTCAAGGGTTGTATCTTGAATTGAAGA TCAAAAATTTATTTTCAAATCTTTCTCGAATTAATCTAAGCAGATTTAGCAAAATTAGAA AGATATTCTAGAGAATGTTTACATTATATATTTCAGGATAGGTGTCTCAGCCATGAAGAT CCAGAACTTGATAGAGCATTGCCAACTATTAAAGAGAATAAACTTTTATTACCTTTTTAG AAGGACTTGAATATTTTGAGGCTGGTGAATAAATGAGGCCTGAAACATTTAAGTTTCTTG AATTTAAGAAGAAAAATGAGTTTAAGCTTTCCAAAGTAAACAAAGTAGGAAAAGCAGCTG AGAAGATAGAACTGTTCAAGATAATAATACTTATAGGACCACTATGCAACTGTAGCAGAT TCATTTTAATTGAGATAGAATTTGACTCCTTAACCAAAGTTACAATTCTGGGAATAAGAA TAAAGTTATGGCTTAGAGTATGACCAATGTGTTTGCATCATAAATGTACGCACATATTTT TTGAAAGGAAATCGAGGTAACATTATGTTATAACTTTTATGCTAGGCCAAAGACTATTAC CTAAAAATTACTCTTCAAGCATTGTTTGAAATGAAAACCATATTTAAAGGTGGTTTGCTG CCTACTGATGAAAAATGAATTCATGTTAAGAAACCAAGGACTTTAAACGGAATAAATTAT AATCAGATGTTAGATTTAGACCAGCTTTAACAAAAACAAATGATTCTTTTCAGAGATGAA AACTGATGGCTTAGCCCTCAAAGCATCTATCTTTTTTCAAACTAAATGTCTTGAGAGAAG GGGATCTGCTTAATTTCATAAAAGTAGGTGTGTGATTTATCAGCAGCAAATTGCTGAGTT TAAGAAATAAGAACTTCCCTAACTCCCCTAAATGTTTCCCTAGGCCTTCTAAATGAGAAT ACTTTGATTTGTAGTAACTTGATTATGCAAAGCTATATTTTGCAGAAGGTTAAAACAGGA CCCATTGGGATCATAGACCAGATCCCTTCTGAATGATGACCCTTGCTGCCTTTGTTTGCA TGTCCACACTTACTCCGTAAACCTCTGGATTATAGACTTGGTCTTCTTGAGTAAAGAAAA TCCTCCAGTTCCACTGGACACCTGCTGATTTACTTTAGCACTTCAGGCCTCTTTTAATGA GATGCAGTATGAGACAGTCTTAGGGCTCAAAAGGCATTTAATAGATCAAGTTTAGAATAT TTTAATGTTAAAATGTCTATCAGTGACTGCTTCTACCATCCTTCATTTCACCTTGAAAAA CAGCTCTTTTAGGTCATAATGAGTTGTGCTAAACACTGAGAGCAAATTTGAATCTCTTAC TTGCCTCAGAGTAATTAAAAGAGAGAATTGTTTCCTCACATTTCTCTGTAATCATGGGGT TAAGTTAAATATGGGATAGATGGTAATGAGTACAACTAGTTAGGATTATAGGAGGCCAAC TTGACTGATGGTTTGGAAATAAGTAGTGTTGATTTCACCATGTGATTCCAGTGGTGTCAC AATGCTTGAGACTTACCTGTGTGTAAAATTTACCTGGCATGCTTGCAAAAATGCAGATTC CTGGGATCCCAGAAAGATTAAAATTCAGTGGGATCTGTGGGTGGGGCATAAGAACTTGAT TTTTCTCGTGAGCACCCCGCTACCTCTATGTATCTTCAAGTAAGTTGGTATGCCGTCAGT CCACTGTAGAGCGTAATAGTTGATACACTGAGTTAGTCAGTGTGTCCAATGAAAAAATAT ACATTTTGTGGTATAGTTAAATGTATTAGCAAGTTAAAAGATGGAAGGATCATGCAGATT AATTATCCATTTGGTAGTTCACAGGTCAATTTTGTGGGGAGGGTGAAATTATATAGAATG TACATTGATGGAGGTGGAATTCTACTTGCAGTGAAAATGCCAATCTTCCATAATAGTTAT TATCAGGAGTGGGAGGCCAATAACATTCTGTTCGTTCAATTTCTAAAATCATGAAGTCAA TAGAAAAGTGGGCAACTAGTTACTCATTTGGTACTTAAGTAATTAATGAGTAATTTAATA CTTAATAGGTAATTAAGTACGTAATAAGTATTGCCAATATTAGTTAGGCCTGTGGAGTTT TTCATAACGGTCTTCAAATAAGTTCAGATCTATATTTCTGTTATGTGCAAGGGGGTCCCT CTTCTTTTTTGAATGCTTCATCTACTCACTGCCTTTCCATTTGTTTGGCCTTTCTTTGCT TCTGCTTTCTGACTAATTCTGCACTTCCAAGAAGACTTCAAAGCAATAGAGCCCTCCAGA TTTTTGCCACATGGATGGTTCACTTAATTATCCTCTGATAGTCCTAGTATTGTGTGCCCA GTCCCACTGGGGAGAGGTGGGGCAGTAGAACTCCTGAGACTTGCTACTGCTGTATTGAGG GCCACAGTGATAAACACATTGTTGTCTTATAGTCTGTTTGATATTTAGACTACTCAAATT TAACCATAATCTTTAAAAATAAAATGTAAATATAAATACTATTAGGTCATGAACAAAAAA AATTAAGCGGCTGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGG CGAGTGGATCACGAGGTCAGGAGATCAAGACCATCCTGATCCAACCCCATCTCTACTAAA AATACAAAAAAATTAGCCAGGAGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGG CTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCTGAGATCACGC CGCTGCACTCCAGCCTGGGTAACAGAGCGGGGGAAAAAATAAAATAAAATTAAGCAAAGC ATAATTTCCATCTTTACAAATCCTGAATGAATATTAGTTCATGCTTTTATGTCTTTAGAA AACATAGTTGGAATGGTGTCTTAGTCTGTTTGGGCTGCTATAGCAGAATACCATATACTG GATAGCTTATAAACAGAAATTTATTTCTCACAGTTCTGGAGACTGGGAAGTTCATGATCA AGGTGCTGGCAGATTTGGTGTCCTTTGAGGCCCGACTTTCTGGATCAGAGACAGTGCCTT CTATTTGTTTCCTCATGTGGTGGAAGGCAAGAGGCACCTATCTATGTTCTCTCTTATGAG GGTGCTAATCCCATTTTGAGGGTACCACCCTCATGACCTAATGACTTCCCAAGGGCCCCA CCTCCTAATAGCATTACCTTGGGGGTTAGCATTTCAGCATATGACTATGAAGGCAAAACA TTTAGACCAGAGCAAATGGTCTAGGCCAGATTATCACACTTGTCCTTTGTATTCTCTTTG TGGTGTGAGTACTAAGCTAAAATAGCCTAGAATATTAAAAATCGTCACGTAATATATACG CATAGTTTAAAAATGAAATAGTATAAAAAGACTTATGATGAAAACACAATATCCTTCCCC ACAAAACATACTCTGTTCCCTAGATGTAGCTGCTTTTTATTCCTTGAGCTGTTTCTTGCT GATTCTTCATTTTCGAAATCTGTTTATTGCATTCTCCCCATTCATTACCTTTAGCCATTG TCTGTTGTATTCTTTTGTGGTAGAAAGGATTTACCTTTTATCCTCCTCTGTTTTCCCAAT AAAGTTTAATGACAAGTTTTAGCTTAATCAATATTCAGTGTGTATATTTTATTTGTCCTT TGGTGTCTATGGGGGATTTGTTCCAGGACCTCCTATGGATACCAAAACCTGATGCTCAAG GCCCTGACATAAAATGGGATAATATTTGGATATAACCTGTGCATATCCTCTGTACACTTT AATCTCTAGATTACTTACAATACCTGATACAATGTAAATGATATGCAAATAGTTGTTATA CTGTATTGTTTAGAGAATAATGTCAAAAAAGGCTGTATTTGTTTAGTATAGACACAATTT TCTGTTGAATATTTTTGATCCACATTTGGTTGAATTCACAGACATGGAACCCAGGGAATG TGGAGCGCTGACTCTCTATCATCTATGTTGTTGTTTCCTGACAAGCAACTAATATACAAA CATTTCTTTTCCTTTTTTTGTCAGAATTTTGTTTTTCCTGGAGTTGGTAATTGCCTTGTT CTTTTCTTCCCCCTTGGGTTTAATATTTTTTATACCTATCACAAATTCTTTCTACACTGT CTAATGCTCTCAGAACAATTTTCCACATGGTTAAGATTTCAGATAATTAATCAGCTTTTT TTTTTCCCTGACAACTTTCCTCTTTGAGGCCTGTTGGCCTGCTTCATCCTTTACTATTTG CCTTCTGGCCTGGCTTCACAGCTGTCATCATGGAATTTGCTCCCATCCTGGGAATTTCTC CTCACTCTTTTCTATATTCAATCCCCAGTTAATTATATAAGGGAAAGTCTCAGTTTCTTG GCTAATTTATTCAATTTGATACATACAACCCCTACTAATATATGGAATCCAAGTAGTAGG GAGGTAATTTTTTTCCCCTTGCAACTTAGCGTGCCTGAAAATTTCACCATATCCTTCTAC TTAATTGTGGGTTTAGCCAGGTAAAGAATTTTGGGTTGAAAATAATTTTTCCCTGGGGTG GGGGAGGGGGGAGGGATAGCATTGGGAGATATACCTAGGGCTAGATGACGAGTTAGTGGG TGCAGCGCACCAGCATGGCACATGTATACATGTGTAACTAACCTGCACATTGTGCACATC TACCCTAAAACTTAAAGTATAATAATAAATAAATAAATAAAATAAATTTTCCCTAGAATT TAAAGCTTTACTCTCTTGTCATATACCATCTCATGGCTTGAATGAGAATTCTGACACTAT TCTAATCGCCTGTGACTTGTTTTTTTCTCTCTGGAAGGTTTTAAGATATTTTTATTTCAA ATGTGAAATTTCAGAAGCATATGCTTTGAGTATTTTTTCTTTCAGTTACAAATTGAATTA GCTCTACTAATATGGAACCTTATGTTTTTTGGTTCTGGACATTTTCTAGTATATTTCTTT GATTAAAAATACATTTTATAGTCTGTTTTCTTTTTCTGGAAATTCGGTTAGTTGGTCTTG GATTTTTTAAAAAGCTATTTCCTCCTATATTTTATGTATGTCTTGTTCTTTCTGGGAGAA TTTTTAAAAATGTTTCAAATCTTGGATAAGATTGTGATATTTTTGTTCTCTAAATGTTTC TCTTTTAAAACTGTCGGCCTGGCGCGGTGTCTCACGCCTGTAATTCCAGCACTTTGGGAG GCCGAGGTGGGTGGATCAGCTGCGGTTGGGAGTTTGCGACCAGCCTGCCCAACATGGAGA AACCCTGTCTCTACTAAAAATACAAAATTAGCCGAGTGTGGTGGTGCATGCCTGTAATCC CAGCTACTCGGGAGGCTGAGGCAGGACAATCCCTTGAACCCGGGAGGCGGAGGTTGCAGT GAGCCGAGATTGTGCCATGGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCAAA ATAAATAAATAAATAAATAAATAAAACTGTCATGCTACTGTTTTTTCTTTTGGGATGGGT GCATTACTTTTTCTTATCTTTCTAATATCAATTGTAAGTTAAAAAATTATCCCATCCTCC ATTCTCTTTCCCCATTTCCCAGCCTATCCTTCCTCATCTTCTCCACCTCCTTTATCCTCC TTCTCCTCTCTTCTCTTTCCCTTGCTTTCTCCCTCCTGTCCTTTTCGTCCCCCTTCGCCT TCTCCTCCTCCCCATTCTCTTTCCCACTCCTCCCTCACTCTTCCCCATCGGCCTCCCTCA CTTTCTTCTCTTTGTCATTTCCTCATCTCCTTCTCAATCTCTTCCTTCTGTTATTTTGTT TTGCTTTTGCTTATATTTTGGATTGAGGCAGTAAAACTGTTTCTGCTTTGGTGTGATTTG TTGACTGGTCCTCACCAGCAAGGGAATGACCTCGTATGCTGATACATTTCATAGTGAATA ACTGCTACATGGCTGTCTTATGATAGTACAGTCCGTAACAGGTAGAGCATTGCATCAGCT GTGCACCTGAATTGGAATATGATGCCCTAGAACTGGACATGTGGAGAACCCAGGAGCAAT CTTGAACTCGGAGGAAATAGCTGTCCTTCCTGGTTTTCATGGTAATGTATGGGACTTGAG CAAGTCTAAGTCACTGACACTGAAGCAGTAGTGTAGATATGTACTATTTTAGAAGATCAT TTACTGAAGAAAGGACATTTCCTAAAAGAAACAATATATGGGTATCACTGGTATTATACT CCTAGTATTATACAACCCCTTTGTGGGTGTTCTGGGCCCTGAACACTAAATGTCTGTATC ACTACCCCCTTTTCCTCCCGCATTCTATAACAACCATAAAACTACTCCCCACCTCTCCTG CTTCCACTGCCCCAAAACCACCTATTTCGGAACACCTGTGTGAAGAGTGGGACCTCCCCT GGTGAAGAAAGTGTTCGCCAGCTTACGGGATTCCCTTTCCCTTTCACCATCACTGGAGAG CTCCCCTTCCTCCCCTGGCCTGTACCATCTGGCTCCTTCTAGGCACAGGTGCTATTTCAA GTGCTCTGAGGCATTGAAAAAAGAAAACGCGTTTTGGAATCAGACATTCATGAGTATTCA CAGCATTGTCTCTGCCCAGAATTCCCTTTCCCCATGTCCTCATGTCTACATTCTACATTA AATAATCAGTTCAAAAGTCTCTACAGTAGTTATTCTTTGAATTCCTGTGCTTAATCATCT GTGACTCTTCTGTAATGTTTTAGTCTTGTCGTTTTTATTACACAACTATACGTCCTTAGA GGTCAAAGTAGAAGGCTTCCATTTATTAAATGCTTACAGGGTGCTGCTTTGCATATTTCA GGGGTAAAACAGAGCTTGAAGGAGATTGAAGAATTTGCCCAGAGTTATGCCACTGGTAAA TGGCAAACCTAGATTTGAACCTAGACTTTTCTGGTTCCATAACTTTTATCTCCTCTCTCT GTGCCTTGTTGCTAAATAAATTTGTATAAATAAATAAAGAAATACATAAGTATTTTAGCA TAAAGATGAATAAGCAGCCCTGATGAAAGCAGGCATGTCTCTTCTTTGCCCTCTGTCAAC TTCCAGTTTTGGTGGAGAAAATAGCAAAACAGACTGCCTGGTCATGGATTTCTGCATATA ACCTGAACTTTAAACATGCCTGGAACACATTTGGTTCTGATTTAAAACAAGTTGGCTTGC ACCATTGCCATGTTATTACAAATACAAAAGAAATATAAACTTCATTCCATTAAATAACCA TCCACATAAACTCTTAAATACTTTCATGGCTTTGGGCTGGGCCAAAGCTGGATATTAAGG AAATGATTATTAATGTTACATATTTTATTCAAACTGCTCTAATTCTTTTAACCTTCCCTC CATCCCTAAAAGTACCAGTCAACCTTTTCCTTCCTCCTGCAAAATGTTCCCAGGAGGTTA AAACAGATAGAACTTTGATTTCAAGCTACTGACTCTTACTATTTGGAAATACTCTTTGTT TTCAGTTCCTCATAGCCTGTAGCTGTGTGCTCTACTTGAAACTTTTCAATCCTCCTTGGA TGACAGCAAAGTTAGTTATTATTCCCTATAGCGGTGCTGTACAATGGAAATATGTGAACC ACAAATGTAATTTTATGTTTTATTGCCACATTAAGAAGAGTGAAACAAAACAGGTAAGAT TAGTCTTATATTTCTTTGTTTAACCCAATATATAAAAGTAACATCATTTCAACATGTAAT CAAAACATTATTAAGATTTTTTACATTCTTTTTTTACTACGTTTTCAAAATCCTGTTTGC ATTTTATACCACAGCATATGTGAATTCAGACTAGTCACACTTTCAGTGTTCACGAGGCAC ATGTGGCCAGTGGCTGTCATATTGGATGGCGTAGCTCTATAGGAAGATCAGCATAAGCTC ACTGTGGTGTATTAGGTATTCCTAATTCCATTAAACTATGAACATTGTTTAAATTTTGGT AAAGGGTTAGGGTTGTTTTTCTAAAAAAACATTGAAATTATGTAAATACCCAAAGTCTTC AAATAGTGTTATGACCTCAGGCCAGACTAAACGATGCTTCAGGGATTGCTTATATAAGAA GAAATAGTGTCTGAAAGCAAGGCATTGGACATGACCAACGTTTCTGTTAATCAGTTGGAC TGAAATTCCATTGACATATGTTAGGGTCATCAGTCCACCAGGAAGTCTTCATTGTTAGGC CAATAAATTTGAAGTTCGAATAAACCCTTAGCAAGAGTTACTGAAAGAGTTCAAGTTAAA AGTTGCTTAAAGCAGTGAGTAATGTAGATGTTCTCAAATTTTTGGGAATATATATTTCCC TACATTTGATAGCAACAGATGCTTTCTGAAACTAAAATCCCCTAGATGAGAGAATGCTGG CCTTTGCTTGCTTTCTGTTGTGCCCTGAGTGTGACAGGGTCAGCACTGTCTTAGATTGTT CCTGGCATTGGAATATTGGCAGGAAAAAGATTTTACATGTGAAAAAATGCCTTGCAATCC ACATTTTGAGAAGTGTGTGTAATCTGCAGAGTCTTATGGAGCAGCAGTGGTCCCCACTGT TAGACAGATTAGGAATCCTCCCCCTAACCTCCATCATAATCTTTCTAATTCTTATTCTGT TAAAATATTTTGTGGGAAATGAAATTTTAAAACACAGTCTCAAAGGATGTCTTGGATGGT TCAATTATTGGCCCATCCTCTTGTCCCAAATTGCCATGGATAATCTATCTAGCTCTTTTT TTTTTTTATTCTGAGCCATAGAGCCCTTTTATAATGGGGTAAATTTCTGTTTTATTTCGT GTTTCATTTGATGTGACCTTTCATTGAAAGTGGGTTTTGTTTTTAAACAGCCTAGAATTG GAAATGTATGCATATACATTTTTCTTTTTGCGGTTCACACATTTTGGAGGGTGTCTATTT CTGTCTTCTTTGGCTAGCTATTGAGTTTGGATATAACTCACAGAGGTTTTCCAAATACTA GATTGTTTACTGTTTTCAGCTGTGAAGATTCTACTATAGGCCTAAATGATTAAAGCTTCT CCACTGAGAGCTGCACAAAATCAGTGTTTCATTCTAGAAAGTACTAGGTTGGTTAAAGCC TAAGATCTATACCTGGCATGATGTTATTGATTGTCCATTATCTATCTCTGATATTGCGTT AGTCATTGTGTCTCCTTAGGCAGCTTATATCTACATTTGATTTTCGTACTTTTGCCAATG ATTGCCTTATACACTGTGGGCTGAAAATAATGCTGTGACAGACCAGTAATGGTGAAACCT TGGTTCATTCTCAAATAGGAAGGAAGATTTAAAAATAATTTTTACCTGAATGTTTTCTAA TTAAAAAGCAATTCAAGCTATTTAAAGGTATGCTGAAAAATACAAAGAAAAAATGATAAA CAGACCCAAGAATTCTACCACTCAAATAACAAGTGTTATTAATATTTTGGTATTTATCCT TTCAGTCTTTTTTCTAACACATTCACTATGTATCCATATATCTAAATACATGTTTGTTTA TATTTGTGTCTGTATATGTACACGTACAGACTTTTATACAGAATTTAAGTCATTCTGTAC ATTCTGTTTTTTTGTTTCTTCTTTTTTTTTTTTTGAGACAGAATCTCGCACTGTTGCCCG GGCTGGAGTACAGTGTCATGATTTTGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGAG ATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCTCTACCACTCCCAGA TTATTATTATTATTATTATTTTGTATTTTTAGTGGAGACAGGGTTTCACCATGCTGCGTA GGCTGGTCTCAAACTCCTGACCTCAGGTGATCCTCCCACCTCGGCCTCCCAAAGTGCTGG GATTGCAGGTGTGAGCCACTGTGCCCAGCCTGTACATTCTGTTTTATACTTTAAAAAACC AAGTTAAGATTGCATTTTTGACCATGGGAATTTAACTGCAAAAATAAAACAATATTTAAG AAAAAATATTAAAGTGAAGAAGAAAGCCATCCTTAATCCAGCCACTGTTAAGAGAAAAAT TATATTTATTTTTGTCTATTCTTAATTTTTCTCAACAGGCCTATTTATTTAATTTTTTAC AGGCAGGTGAATTTGAATTGTTCACAGTGAAGACTGGTAATTAGAGAGGGAAAAGATAGG GTCTGAAAATTCTCACACTTATGAGATACAGCATTCAGATGATACTTTTCACCGTTGAAA TTTAAAGTTAGAAGTGTTCTTCAGTTGGTTAGAGTATTTTAATGATGACTATGATTTTAA TTCAGAAGTGGAAGAAACTTTAAGAATGAACCTAATGACTACTCTTTTCTCAGTTGGCTC TCAGAGCTTTGCATGCCATTCCAAAGTGCAAGGTATAATTCATGAACATAAAAAGTTTCT CTGGGAATGTATAGAAACTGCATCTTCTACATCTTTTGTGCTGATTCCTCTTTCACTTGA ATTGGCTGGGTTGTCAGGGAAACAGTTAACATACAGTTTTCTGGAAACAGTTAATATACA GAATAAAATATATGGCATAGCTCTTTTAGCATATGGATTAAATTGATACAATAAGGGAAT GTTTTAAATTTTGTGTAAAATATTTTTGCACAAGAATCAGGCTACCTGAATAATTGTTTA TCTTTCAGGTGACCGAAAAGCACAGCAGCCCTCTTAGTTGCAAATGTGTTGAGTTGTGTT AAAAAAAAAAAAAAAAGATGGAGAGGAATGCCCTGATTCTTTACAGATTTGAAGAATTAT ATCTCAATTAATTTTATAATTTGAACTTGGTATTTTCTTGCTCAAATTCCAAAGGGGAAG AAACCCCATTGTTTATCAAGGTAATGTTTAAAGATGTTTCATACTATGTTATAAATATGA AGAACATAGTCCTTGTGTTTTTAGAGTTGGCTCCATAAAGCATCAGATGTTATAATAGAA AAGCATTTCAAAATGAAAAGGATATTTAAACAGAAGTTTCCATGTGCCCCAGGAAGAATT TAAAGTCAAGCTACCCCCCTCCCATTTAATTCAGTCATTAACTGGACTTGCTCTGTAGTT TGGGGGGATTGTAATAGTTTACACCTGTTTCAACTTTTGCTGTTTTTATTGGCAGTGGCT TTTGCCATCCCATATTTCTTGTGAAGCAAAAATATGAAATAAAATATGGCAAAGCATTGG AGAAATTATAATAAACATAAAAAATGAATCGTTCAGCTTAAAATATGAAATGCTTTACCT GCACATTCAGCCAGCCACGTTTCAGTAGTATTGAAGTAATTTATTCCCGGAGTTGTGTGT CATGAAAATAAAGACAATTGCTTTCATTGGCAGGAATAATCCAGGGTTTTTACATCCAAG CGAATAAACTTTGGAACATCAGGCAGACGTTATATTGTAAAGACAGTTTAAGGAAAACCT GCTAAATCATTATATCTGTGCTCATGTCACTGTGGAATAAAAAAGATGAAGGAGTATCAG TGTCTAAGATTGCAAAGACTCAATAGAAGTATTTTACCACAGAGTGTAATCAAACTTTAA AGGTCAAGCAATATCATGACATAAAGTATGGTTTGGCTCATTTCACAGGCTCCATTTTGC CCTCCAAATATAATGAAAAGGAAATGATTTGAGTCAATATATTATCATATCTCATATATA TTTTTTTCTTCCGATCCAGCTCTCTAATGGTCTCCATATAAGTGCCCTTTGTTCTTCAGA TCTAACGGTAGCTGTCCAGCTCCAGTGTTGGGTTCGGAGTGAAATAATTAAGTTTTTAGT GCATTGTCTAGAATGAGAATTGCTAAATTAAATTTATAAGTTTAATTTGGTTAGAATTGT GACTGTGAAAAACTCTCTGGGAAAGTTGCTAGGAGAACTGAATTTTAACTTTGGCTTAAT CTCACCAGTTAGGTTGCTTTGAATATTTTACAGGTTGGGGTTGTAATTTGAATGAAGGTA GGGCCTTGCCTATTTTGATTCATTAGCATCGAACCTAAGTCCTAAGTATTTGCAGAATGA AAGTGTCAGCTTTTCTGGGTCTGTAAAATGAGCATTTTATTTTATTTATCTTATTTTTTT TAAATGAGCATTTTAAATGCCTAATTTTATATTGAGAAAAATGTTCTTCAGTGATACCCT TTTCCCCAATCTCTCACTTCTTGGAAAGACTTTATATTTTGATACTAATGAATGCAGACT AAGTGGGAGAAGTAGACTCTCAAATTTGGGCTCAGAAGAATCCGTGTTTGGGGGAAGAGA AGAAGACTTTTAGTGAAATGTCACTCTCTTAATAGGCTCTCATGGCCTTTGTTAGCTTTG TCTGCTTGGGGTCAGTGAAAGTCCTTCAGGTGACCTGGCATCCTGGGAGTGAATTGAGTA TGCTTCTCCCTAGGAAGGGCTAATGATTGGGACTCAACACCGTTTGCACCTGAGACCATG ATCTAACCAACAACTCATCAGCATCTTTTACCAAGGTATTTATGGGCTTGGGAAATGGAT ACATCAGAATTGAGGTAAAATCAGGCTCAGATTTAGAATTTCTTGCACACAAACACTTGG AATAAAAAAGTCCAAAGATTTTTGCTGCCAGTGAATGTAATTTGCCATTTCTGGCTTCTT GCCTGCTGTTTTCCCTCAAATAATAAACTTGCTAAAGGTGCAGGTTTCTGGTTAAATTTT AGTGATTTTTTTTCACCTTGGAACAGAGGTAATAACAGTTTAGGTCTAACTTAGGAAATC TTTCCCTTTTTATTCATCTGGAGGTTGAAGGGCCATTCTGTGAAGGGTGTTTAGTGTTTT GATGGACTTGGAATGAAGGGGCATGACAAAGTGTGATGTAATGAGTTTGTCTTGAGCAAA ATAAGTCTCCTCAAGGAAGTTTGTGTAATAAATATAGTTGTATAATGAAATTTCAACAGA TGAATTCTAAGTTGTGAAGGAATTTCCTGTGGTAAAAAGGGCAATTATCTACTTTGCTTG ATAGACCTTTGAAAATATATTTGATTCTAAAAATTTCTTCTCACAGAAGAGTTTCCTCAA TGTGACTAGATATTTTTTTGAATCTCCATGTCCTTATCTGCTACTTTCATTGCCATGTGA AAGTGGGTATCATTGAGGGTGGCTCTTTTAAAACTATTTTTAGCCTTAGACAAAGACAGC CAAGAATTGGCTAAGTGCCCCCCCGAGACACTTTTCATTAGGTTTGAGCACTGACCTTTT ATCTTGCCTGGGTGTTCGCTTTAGCTAGGGCCACCCACACTTGCCAGTTTGCTTAGAAGT TTGTTCAACTTTACTTTTTATGTTTTCATTGAGCTTTAATATTGGCATATTTTAAAGTTA CAGAATGAAAATCATTGTTTGCAGAGCAAACTACAGATAATTTATTTGTAGAAATGTGTG ATTCAAATGGCCTCCATCAGTGTGTAAGGAAAATGGATGTGCCGCAGTCAAGAATACGTC GAGGCAGACATCCAGTTCAGCATGACCCAGCGAGTTTGGAGTGCAGGCTCCCAACTCCAC TCATTATGTAACCACGCCACATGAGGCGCATTAGGTGTCCACCCACATGAGCTCGTGCTT TGCTCAGAGCCACTATTGTCTGTAAAAGGTATAATTACCCTGCTGACACTACATGCAGCT TGTGCCCCAGTCGGCTTGTTCGTGCCAAGAGACAGAATAAAGCCACGTTGAAACCCCCTA CGATTCCTTGAGTGTTCTTTCAGCTGTCCACCACTCATCCACCCACTCCTCAGTCCTCAG CTTGGGCTGGAACCTAACACTTGGCATGACACTTGGCATAGTCAGCAGGATACTGAGGAG AGAGAGCCTTCGGTCCCCACTGATTCCAGGTTGGGCATGTGACTGCAACATGAGTTATGG TGCCCAGTGGCAGCTGTACTGCTTAATGGGCTCTGGTGGAAACCTAGGTGGTGGCAGTAA ATCGGTCCCCCACGAGCATGGAAGAGGTGCTGAAGCAGCTGCAAGTGCAAAGCCCTGAGA AGGAGTGAGCTTTTGCTGGCAGAGTTGGATAGGCATTTTTGAATGCACTATGAAAAGTAC ACACCCAGTCCCTGAGGGATGCAGCAGAAGTAAGGGCCCTCCAGGTGCAGGCTGGGTGCC TGGAGGCCTGGCTACACAGCTCAGCAAAAGATTTAGAAGCTGCCGTAAGTGGGGACCTTC AGGTGCAGGCAGGGTGCCTGGAGGCCAGGCTACAGAGCTCGGAAAAGGAATTAGAGGCTG CTGTGAATGCAGGCCTGGGGCTGTCGTCTCAGCTGGAGACCCCCACTCTGATACCGAGGA GGCTGTTAGTGAGACCGAGGGGTCTGCTCCATAAAGAAGGGGAAGATGCCCTGCCTGCAG GGGTCCCCCCACTGGAGAACAGGGGGCCCCAACAAGTGACATGCTCAGAGATGTGGATTG ATTTGGTTTTGGCCAGGATTGACTGAGAGAAAATTGATAAACAGCCAAATGAAGTACTCT TAACTTTGTGCAATTCCAGAAAATGCCCCAATGGGAGAAGGACATTGCTGCACAACCTGG TCCCACCTGGGCGCTTCAGCTCAAAGACTCCGTATGTGCTACAGCCAGGTGGGGGTGTAA AGCCTTTTCTGTATGATGAGGGAACTGGCTGAGGTTCGACTTAGGGGAACACCAGATGAC TGGAGGCCACATGTGGAGTTGACAGTCCATTGTTACCCCACCAACATATAGCAAGTGCTG GTGCTGGTAGACACCAGCACAGATAACGTTTTGGGCATGGATATTTCACATGGCTTGGCA GCCATGCTGTCTATCAGTGGGCTTGACAAAACTGAGACAGTACCACTTTGTGGTGGACTT GGCCAATGCATTCTTTTCCAGAGAGCCAGGAGCAGTTTGCCTTCATGGGAGGGCAACAGT GGACTTTCACAGTGTTGCTGCAGGGCTATGTGCATAGCCCCACCATATGTCATGGTCTTG TTAATGATATTATGCTAACTTCTGATTCTCTTGCAGATTTAGAAGTGACAATGCTCCCCT TGCCTAGATTTAAGATGGTGCGGCTGAGACCACCTTCCTGGCAGCCAGGTGGGCTATTCA GCAGGCACAAGCCCTACGGGTAGTTGACCAGGGGTACCTGTTTGAGCTGGATGTGCATGT GACCACAGATAGTTTTGGCTGGGGCCTTTAGCAGCGCATGGAGCGCTTGAGAATGCCAGT AGGCTTTTGGTCCCAACTGTGGAAAGGAGCTGCGCTCCAGTATTCACTGTTAGAGAAGCA GTTAGTAACTGCATATGCTGCCCTTCAGGCTCGTGAGAGTACGGCAGGATGGGCTACAGT CGTCGTGCGGATGACTTAGCTGATAGCGGGATGGATGCATTCATGGATAATGACTCCCTG AAATGGGCTAGCACAGACATCCACTTTAGCAAAGTGTGGTGCCTACTTGGAGCAGCAGAG TACACTGAATACAAGTCCCTTAGCAGCAGAGTACACTGAATACAAGTCCCTTAGCAGCAG AGTACACTGAATACAAGTCCCTTAGCAGCAGAGTTGCAAGAGGTCTTGGGACTTGTAGTC CTAATGGAAGATAAGGCCATGGGGCCTGAGGCACCCCTCCATTCCTGATAGAGCATGGTA TACGAATGGGTCTAGCTGGGGTGCTGCTATTGCCTGGACTGCTGTCACAGTTCACTCTAG TACTGACGCCATATGGTTTGATACCAAGTGTGGACAAAGTAGCTAATGGGCTGAAATCAG GACAGCATGAATGGTGATCACCAAGGTGGTGACACCTACGGTAATCTGCACCGACAGCTT GGCAGTTTATTGAGGCTTAGCCTTGTGGTTAACTATCTAAAAGTAACAGAAGTGGCCAGT TGGTCACTGGCCCATATAGGGCCAAGCCATGTGGCAAAACCTATGGGAGGAAGGATGACC TCCTCTGACCAGGTACAGAGATGAATGGTAACCTGTTGTTGCCTGCCCCAGTGCTCCTAA AGGCAGGGAAATAAAAGCTTGGCTAAATGTACAAAGCAACATTGGTGTAATGTCACCATG GGGTGGTTGCCCACCATAACCTGGAGTTGTTTTTCCCTGTATTACTGCTGTGGCCTCTGG GTCCAGGGTTTCACCCTTTGGGCATGTGTCCCCACTAGAAAAACTCCCTCTGCCTAGGGG GTGGAATGTAAGACCTATGTGTTGGGCCTGAGTGTCTGGGGCCTGTGTACCTAGAGCCTA TGTGTAAGGTCTTGTGTCGGACCTGTGTGTCTGGGGCCTGGCTTGCATGCCCAGAGGCTA TGTATGAGGCCTGTGTGTTGGAGCTGTGTGTCCAAGGCCTATGTCTCCCTTGGCCTAGGG GGTGGAGTGTAAGGAAAATGGATCTGCTGTGGTCAAGAATAGGCCAAGGCAGACATCCGG TCTTGCATGTGAGTCTGGAGTTTGGAGCGCATGTACACAATTCCACTCCTTACATAACCA CGTCACGTGAGGTGCATTAGGTGATCACCCATGTGAGGTCGTGCTTGGCTTGGAGCCACT ATTGTCTGTAAAAGGTATAATTATCCTGCTGACGCTGTACATATGGCTTGCGCCTGGGTT GGCTCGCGCCCAGGTTTGCACCCACAGTTCACGCCCAGGCTCACTCACACCAAGAGAGAG AATAAAGCCATGTCACAACTCCCCATGATTCCTCGAGTGTTCTTTCAGCTGCTCGTCATT CATCCACCCCCTCCCCTTGGTCTCCCGCTTGGTCTGGAACCTGACACTTGGCGTGACACA GTGTCTGGGTGCAGTTCATCCTATTGATGATGTGGAATTTGTGCAAAAATAAAAGTTAAA AAGACATTAGCATTATAGGTTAGTTTGCTTTTGCTGCTGTAACAAGTTGCCACAGTGTAG TAGCTTAAAACAACAGAAATCTTACTTTTTGGGTCTGAAATTTGAAGTGGTTTTCACTGG GCTGAAAGCAAGGTGTTAGCAGAGCTGTATTCTCTACAGAGGCCATAGGGAAAGATAATT TCTTTGACTTTTCCAGCTCTTAGAGGCCACCTACATTCCTTGGCTCATGGCCTGTTCCCC TGTCTTCAAATCTTTGTCATCTCTGATCTGTCCTTTGTTGTCATGTATCCATCTCTCCTT GTGCTTCCATTGTTACATCACTTTCTTGTACTCTGAGCCCCCTCCTTCTTTCATTAAGGA CACGATTACATTGGGCCCATCTGGCTAATTCAATATAATCTTCCTATCTTTTTATTTAAT CACATCTACAAAATCTCTTTTGCCGTGTAAGATTCCAGGGATTAGTACATGAACACCTTT GCTAGGAGTCATTATTCAGCCCTACCACATATTAGAATACAATTTTTAAATTCCTTTTTA GCCTTTGTTTTTATGTTTTCTCAGATTGCCCTTGGAATTTCCAGAAACATGTACTCTGCA ATCTGTTGTTTGGATAAAAATGTGTTGGTAAAAAATACACATTTCTATAAAAATAGAGAA GATGTCTTATATTTAACTGTAAAATTTAAGTTGGTGAAAAAAGAATGTAAATACTTGTTA TTTCTTTGAGGGCAGAGAGAATTTCTCAAGTTTTGAATCTTTTTTTTTTTTTTTTTGAGA GAGTCTTACTCTGTCGCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTC TGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCTCAAATAGCTGGAACTACAGGC GCACACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTT TGCCAGGATGGTCTTGATCTCTTGACCTTGTGATCCGTCTGCCTCGGCCTCCCAAGTTTT GAATCTTTCACTTAACAATGTCAAAATTATGGTAGATGCTTGTCAAAACTTGCTAAGTGA CAAATGTGATTCTTAAGTGATTGCTCTGCCACATTTCTTGGGTCTTTAGTCATTTTAACA AGTGTTCTGGACACACACACATATGCACTTCTGCACACAAACATGGCTGTGCTGAGGTAT TACCTAGCAGGTGTTTGGTTTACCGTGGTCTTCCAGACTTTAATTTCCAGTAGTTCTCAC TTCAGTACCTTTCTTTGTCCTGGCCAGGCTTCTCTCATTAATCACTATTCCACCTACACC TGAGTCAGAGTCCTGTTTGGCCTTAGAAAGATGCAGTCTGAGTCTGTTGCAAGCAAGATG CTATTGGCTCTTTATCACTTCTCTCCTTTTAGTCAAATTCCCCACCCCTCAAAACAAATG AATACAAAATGTTCATAGTCACAAGACTTATGAACACAGACTGAGAAATGGGTTTGTCTT GTATTTATGGGCTACCATTTATCTATAAAAATGATATGAAAATACAGTGATATTTTAATT AATGTTACATGCAATTTTATTGTTGGCTGTGACCGTCACCATTACTGTTTAATTCTCATG TTTTTTTTTCTCTCTTTGTATATACAAATGAAGGAGTGAATTAAAAGTATATGATGCCAG CTGAAATTCAAGTAGATTATATAGACTTTATAAAGCATAAAATGGAAACAGCTCAGAAGT AGGCCATATACATGAGCCATCTTTGTGCCTGGGATTGATCACAGATAGGAAGTGCTTGGA ATGCTACAGTTGATTACTTTGAGAGTTGCATTTATTCATATAGTTCTTTAACTATGAAAG GACGAGATCACTTTCATCATCTAAGTGTGCAGGGGTTTGTGAGTCTTTCAGACAAAGCAA AAGAGTGTTAAATAATCCAGAGACATGTAATTGATGGATTGGATTGCTAGTCTTTACCAG TTTTGCATCCCAGTGAGGCATATTAGCAGGCACTGAGCTGTGGGAGAGCAAGGCTGGCAT CTTGTTTGCTTTTGCATTCTCATATCTGATGCTCGAAAGTTTTTTGAATGCATACATTGA AAAAGTATTTTAAATGTGCACATTTTTATTTACAGCTGCTGCTGAAGGGAAAGGCAGAAG TGGGGAAGACTTTTTTCAAAAGGTAAGTTGTCTTTTACTCTTGTCATGGTGATAAGTAAG AGGAAATATACTTATCTCAACAGCTACCCTAGAAGCCACCGAACGCTCCCCTTCATGTGG AGGAGAACAGGTTTCTATACGGGAGCTGGAAACACTCAGAGCTAGCCAGGAAAAGAGGGG ATGCTGTATGAAACTTAACCATTCCAAGAAGGCTCCTTCCAGGGAAAATCTAATGAAATT TTTGCTTAAAGGCAAATAAGCAAAATGTAAGAGGGCTCAGAGGTGGATCAATTCATGTGG CATTCACACTTCATTTGGCTGGCATGTGACATAGGAAGGGGTTATTGTGCAAGGTAAGGT ACACTATCCTATATGGTGAATATGGTGGGGGAGCTTTTCTAAAGATATTTAAATTAAAAC AAATTTTAAAATGTTCTACTGGCCAAATAGAATGTGCCAGACTGCTAGTTTTCCATCCTT TGCTAAATTTATAGGCTCAGGCTGATGCAGTTTAGGTACTGTACCCCCTGACTTGGTGTT ATCTGACATTGGTTAATCTCCAACTTATACTGAATACCCGAGCATTTCTAAGTGCCCTGG CCTTAGCTGGGGCAGGCTTAGCAACAAGGGTAAGACAAGAGAAGACGAATAGGCTGGATG CAGTGGCTCATGCCTGTAATCCCACCACTTTGAGAGGCCGAGGCTATCAGATTACTTGAG TCCAGGAATCAAAGACCAGCCTGGGGCAGGGCATGGTGGTGTGTGCCTATAATCCTAGTG CTTTGGGAAGCTGAGGCAGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCA AAAGCCTGTCTCTACTAAAAATATAAAAGTTAGCCCGGTGTGGTCGCAGATGCCTGTAAT CCCAGTTACTTGGAAGGCTGAGGCACGAGAGTCACTTGAACCCGGAAGACAGAGGTTGCA GTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTTTGTCTCTA AAATTAGAATAGAATAGAATAGAATAGAATAGAATAGAATAGAATAGAATAGAATAGAAT AGAATAGAATAATCCAGCCTGGGCAACATGGAGAAATCTCTCCTCTACCACAAAAACAAA CAAAAAACCCAAATTAGCCAGGTGTGATGATGTGCACCTGTAGTTCCAGCTCCTCTGAAG GCTGAGGTGAGAGGATCACCTGAGCCCAGGAAGTTGAGACTGCAGTGAGCCATGATCGTG CCACTGCACTCCAGCCTGGGTGACAGAGTAAGTCCCTGTCTCAAAGAAAAAAAAAATGAA AAGAAAACAAATAGCAGAAATCATAGATTTCCCTTGGGTTGGCTCTGATGGTAAAAATAG ATGCTGTCAGTGGAAGGATTCTTCTTCATTGTTCTTCTTTAACTCACAGATAGATGTAAA AAACAGATGCTCCACCTTTGTGATTTCAGACAATTTAAAAGCTGAGTCAAAATATGGTGT ATATGATCATAAAGGACTTTCATTCTTAGATTTCCTAATATTTCTCACTGTTTGCAGAGA CATATATACATTCCAGCAGTTTAAATGGAAACACATGTTTGAATCCAGGAACATGTGTGC GTCCCACAGACTATGAGTTAGAGTCATAGATTCTATTCTTGGTCACAGATTAATGAGGTC TCTGAATAACTAGATGGGAGTACATTTTATCTTCTCATTTGTTTCTTTAGTTCAATGGGA ACTGTCTTTTCCATAGATAGGTGTCCGTATAGGATTTGCATACTCATCCAGCAAAAAATC TCTAACTTAGAAACAGCCCAAATTCCAGAGAGTCATTTTTCTGCTATTTTGACTGGACAG AAGTAGACATTATGGTTCATCTACAGTAGAATGAAGTAATGGAGAAATACTGAATTGTCC TCCAGGAACTTGCATGCAGTCACATGTATTCTAGTTTTACATGACATTTTGGGAAGCATT TAAGAAATAGGCTACATAGCTGTTCACTAGCATCTTCGTATTTTTCTCTCTCTAAAATAA TGCAAATATGAAGGATCTAGGCTTGTGATTGGAATGTTTCTTAGTTTTTACTTTGAGGTG TGCATGACAAAAGTTAAAACCTCTCTTTAGCTGAGTTTAAACTTCAGCTACTCAACTTTT CTAAGCCTGGAAGGATATCTACCTAGCTTCATAGTGCCTCTCCCTATGTAGAGATTTGAG AAGGAGTGTGAGACTTTTCATATGTAACTTTATGTTTTTTTGTACCATAAAAATATATGT AAAATCATAATGACTATACTAAATTTTGCTCAATTTAATTAATTGCTCTCATTAAAGTTT TCGAATTAGAAAATAATAAAATTAATTTTAAAAATCTTCCAAAATAAGAATTGGTATATT TCCATAAAGAGCTTGCATTTCAGTTTAACAGATAATAAGATTGTGAAACATATTATCTCA AATTTGAGGCTGTAATAGTAGTTGTTAAGCTTATTATACACTTCTTCCATTGAGTCAACG TTACTGTTTTTTCCAGAGATCTACCCAGTTTTCTATACACTGTTTTGCTGCATGGGTTTG AAATGATATATTTCCCAAACACAATAAAGGATAAAATGTAAAAGCCTAAGATGTTATAGC AAAAAATCCCCAAAACCCCAACAATATAGTGTCTTAAAGAGCAGAGTCATTCGTTGTCCT CTTATGTAACGTTCTAAGGAGAGTCTTCCAGCTGGGTTGGTAGCTGTGTCCCATGCTGTC ATTCAGTGACCCAGGCTCCTTCTAAGACATATCTGGATTGTCCCTAAGCATGACCTTCAT CTCCGTTGTTGAAGCTTGGTCACAACCATGTCCAATTGTGTGTTGGTGAGGGAGATAGAA TATTGAAGAGAGGCACGCCATGGTTGTAACGCCCAGGCCTGAATGTGGCACCTGTCACTT CCTCTCACACTCTATGGGAGAAAACTTAGTTATGTAGTCTTACCTAATAGCAACAATAGA GGGGAGGGAGGGGCTGGGACATTTGGAGAAAACAATTGATTTTGCAGGCACTATTCACCA CAAATGAGATTGTTAGGGAAAAAAAAAAGTCTGTGATCAAAGTGTAATTTCTTTGTGTGG TGTACTTTGAAACTTTTTGTATTTGTTAGGGCTCCCATACCACAAACTGGGTGGCTTAAC TGTGGGAGGGAGAATCTGTTCCATGCCTTTCTTTAGCTTCCCATGGTTTGCTGGTGATCT TTGGTGTTCCTTGGCTTGTGGAAGCAACACGTGGATCTCTGCCTTGATCTTCATATGGCA TTTTCTCTGTGTGCCTGTCTCTATGTCCAAATAAAGACACCAATTATATTGGATTAGCAG CCCACCCTACTCTGGTGTGTGTTCATCTTATTATACATCTGCAGTGACCCTATTTCCAAA TATCACATTCTGAGGTCCCAGGCATTAGTACTTCAACATACGACTTTTTGGAGGACAGTT CAAACTATAATACCTTTTAATGGAGAAAATAATTCTGTAGAAAAATTTACTAAGACTGTA GATGTTATTTGTCACATTTTGATACTCAGTCTGATCTATAGATATTTAACTGCCTAGTCA TTTATACTAAATCTATTTTTTTAATCACAAGTCATTTCTAAATTGTCTACAATGAGTATA TAATTGACATGCAAAAAGAGAAAAAAGTAATCTGTAATCTTGCCTTTTTGTTTTTGTTTT TTGTGTTTTTTTGAGACAGAGTCTTGCTGTGTTGCCCAGGCTGGAGTACACTGGCGTGAT CTCAGCTCACTGTAACCCCTGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCT GGTAGCTGGGATTACAGGCATGCGCCACCACGCCCAGTTAATTTTTGTGTTTTTAGTAGA GATGGGCTTTCACCATGTTGACCAGGCTGGTCTTGAACTTCTGACCTCCAGTGATACACC CACCTCAGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACAGTGCCTGAACTGTAAT CTTGCCTTTGAAAGAGAACTATTTGTACACCCTTGGTCTTTTTTCTGTGTATATTAAAAA TATATATAAAGTGATTTTTAATATTCCCTGTTTGATGGGATTACAGATTAAACTATGTAT TTGCATTGGATCCATTCTGTGTTAAAACTTTGCAAAGTTATCCTGTAATAGTACTTTTTA TTCTTCGGCTCTGACTACACTTATAAAAGGCGGGAATGGATATAACTTTATCAGTACTCT CCGTCCACTCCTGATGGCAGCTCTATCTAATGGAAACACATGGAAACAATCTTCCAGTTT TTTACAGTTCTTTGGGCAGTTGTTCATGGCTTACTCACTGTCTGTCCTATTTCCTTTTAA TCAGTTCTTTTTTTCTTTCTCTTGTGAAATGACTATGGTCAGATCTTGGAGGGGAAAATG GGTTACAGTATTTTAGGTGGGGATAGGGTCAGTGATTGTATTACACATGTGACTCATCAA AGCAAACTGCATTAGGAATCTGTAATCCCAATGGTTGGAGAAGACAAAATACAGTCAGCA TTGTAATTGATGAAAGCCAGGTTTTTTTTTGTTGCATTGGGTTATGTACAGTATTTTTCC TCAAAGTATACATCATTTATTTTAATGTAGGACTATGTTATATTCTTTGAATATATTGGA TGTTTATTTGGAAAACTGACCTATAAACCATGGCTTGTCACAAAGGCTAACAGTAAGACT AAAACAATGAGATATTGATGGCTTATGTGGTTTATTTTTAAAACTTTCAAACTCATTGTT TTTAGACAAACATTACTTTTGGTGTTTTCAGACTGGAAAATAGCAAGTGTTGTCTTCTGG GGGAAATTCCTGGGATAAATAATTTGGTTCCCTCTGTACCTAAAAATGGGTGCATTAGAT GGTCTTAGATGGGGACTAGGTGAGTCCTTTTATTGAGGGGCAGCAGAGTTAATAAAGTTA CTCTGGCTTTCTCCACTAGCGATTATTTTTATATTTCGAGTGGGTTATTTCCTCTAGTAA TGGATATAAGTTTTGGTTTAATTATTTAAAAGTGAATTCAGTTAACTCTGGCTCATGAAT GTGCTTTTTCTAATACTGAGTCTGTGCTTAAACACAAATCAAATTTAATTTAAATAAGAT CCAGATATTTTAAAGCTTTAATTTTAGTATTTATTTCAATAGGTAATACACGTACATGGC TCACAATTCAAATTTATAAAAGGGTATGCAGTGAAGAGTATTTGATATCTTGATGGTTTC TGAAGGTTCACTGAGAAAGCTGTGCAGCATTACATTGTTGGTCCCAAGCTTGGGTAAAGA TGATCATCAATGTGCGTCATTACTAATGAAAACTTAGGGCCTAAAGCTAACATTCTGTGA GTTCTTATTACCGATCACTATACTATTGCCCTGAGAATGTTCCAGTGACAGAATCCGTGA TCATGTTTTCTTTATACTACTGTCTAGATAGGAATAACTGGCTGCTTGTAAGACTTAGAA AAGAAGAGTAACTTTCCACCCCGTAAAGGTTGTTTAGTCATCATCTAGAAAGTTACTAAA GATGAGAATGGAGCTTATTTTTATACCTTATGATTTACTCACCTTCTATCAAGAATCTAG TAAATCAGGGTTAGTGAGAAGAGATTAAGAAAAAGATCAAGTAATTTGCTCATCATTCTC CTAGTCTTTCAAGTTTTGTTCTTGTGTTCATTTGAACACAGGAAGACTGGGTTTTGAGTC TATATTCTCTTAGCATGTTGTAGAGTCACCTGCTTCGAGTTGCATTGTAATGGTATATTC TTTTATTTCATCAGTCATTTCACACAACCTCTTTATGAAAACCACATTTCCTGTATTATT CCTTTTTCTAAAACCATGGAAGCAAGGAATGTCATTGAGATTGTTTAAAAATGTATGTTT AATGGCCAGGCACAGCAGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGC AGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCT GATAAAAATACAAAGTTAGCTGGGCGATGGTGCATGCCTATAATCCGATCTACTCGGGAG GCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTACAGTGAGCCAAGATTGTG CCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAGTATG TTCAATGATAGTGAACGTAACTTAATTACTACTGCAGTTTGTTCAATTGAATAATCTTTA ATCAACATCTGATGAAAGTTTAGTCATTATTGATTAAAATGGTTCCTTGAAACCAAACTC AATGCATTGGATCATGTAGAAAATGAAATTGAATTCATGAAAATAGGTCTTTTAAGAAGG GTCACAAGACAGGACCCTGGATTACACACTTGTAGTGCAAGTAACCATGGAAAGGTCTAG TTAAGAGACTTATTGGCATTAGTTTAAAAAGGTTTGTATATTATTTTGTAAAGTGTTCTC CCTTTATGACTTAAATGCCTACATTAATTCCTGTACTTGTCGGCATTTCCCTTAATCGAA AGATCTTGAGATACAGACTTCCTCATTTATGGTTGATATTAAGATTTTGGAACTATTTCG ACATTATGTAGATAAAAATTACCCTAACTGATAATATGCAAACGTAAACATTTTTGTGTG GGTCAGAAGCAACTTTTGAAGAGGGTGGCATTAGCTGTTTGTGAGGAAGGAGTGCATTTG ATTAGTTCCAATTTTAGCCTTGCCTTTGCATTGTGTGTCTATTTAATTGTCTTTTCAATG TCATGTGATTCAAATTGTTTTTATATCTTAGCGGGGGCATAGGACAAACTTGGTCTTAAT ATATTACGTAGAACATTATCAGAGATGTGTCTGAAAATCCATATATAAAGATATTCATTG TCACAATATTGTAATAATTAAAATAAAATTAAAAATAACCTAAGTACTCAGCCATGTAAT ATTTGAAATGTGGTATATCAGACATTGGATTATTATGTAGGCATTAAAAATCATACTTTT TGGAAATATTTAATGACATGTTGAAATTGGTTACTAGATAGGTACAAAAATTAGGACAAA AGGCATATAAATAGCTTGACTCAAATTTTGTTATATATGTTTATGCCTAATAAATGACTG GGCAAGAATTATGCCAAAATGTTAACCGTGACTCTCAGTGGTGAGATTGTGATTGGTTTT TATTTTCTTTCTGTACTTTCCTACAATGGACCTCCATTACTTTTATAATCAGGATTAAAA ACAACTACCATCTTATGAAGAAAAACAGATAACAATAACTAAGATAGATTGAAGTTGTTA ATGGATTAATTATTGCAGTTTAAGAGCATGCAGTTTTTTTGCTGAAAAACATTTAAGAAG TCAGACTTCCCATCATACTGAGGTTACTTCTGTGTCTTTTATATAACAGTTATAAAGACA GAACAAGTTTCAGATCATCAAGGTGGATCATTTCTAGGTAGTGTTAATTTTTAGAAAAAT GTCCCCCCTTTCATCCATTTGCCCTTGTTTTGACATTCAGAGGTGTAAAATTTTTTTAAG ATTTTTTTACATCTCTGTGCCTTCTTTTCTTCAGACCAAAGATACTTAGTTTCTTATTTA TCATATGACTTAGTTTTCAGACCCTTATCATTCTTTTCGCTTTCAGTAGCAAGATCAGTG TCCCATTTTAAAAGTGGCAACAATATCTGGGTATAGTGTTTTGGATAGAGCCTGGCCAGT GCAATTATAATGAGGCCATAATATTCATAATATTAAGGTGATCCAGAAGTACCTAAATAT TATATAACCTTTAGGCACTGTTACATTGGTCACTGACATGAAGAATCGACATTACTTGTC ATTCTTCACCCAACTGAAGAGAAAAGGTTGGCTCCAATGTCATTGCTAGGTACATAACAT AAAATGAGGATACTTCTAGACTGTTGACTGGCTGGTAAAGGCCTCCATAGATGTCACTCA TATGTTGTGCCTGTCACTCTAAGCTCTTGACCTGACATGTAGCTTGGAGACAATGTGGCA GATGTGGTGGCTAGACTGTGAAAGTGTGGAAAGCCTCACTCTGGGAGATTTCACATGGTT TGGACATTGAATTGATAGTGAGAACTCCTGCATGCTTTTTTCTTCTCTCTGGACTCCTTG AGTTAGCTGGGGGAAAGGACTCAGCCACAGGGTGACAGTCTAAGATGATGGGCTGGGTGT AGTGCCTTTTAATCTGGCTAAAGTAACATGTAGTAAAGAACTTTAAGCTTTACTGATTTA AAATGACTTCACAGAAGAATCAATGCAGTTTAAAGCTGGATGTGGTATTGTCTTTTTCTT CTAGTCGGGGATATCGTGGTCTAAATAGTCGTAGATTGATTTTTTTTTTTCAAGTTTATA CAGGTTGTTGGTGGCAGCCAGAACTTAGCGATATTCTGACTTTATGCTTGGCTACTATTA ATACAAGATAAATGTTTTTATTTAAATCGGCAATTATCATGCCCACATTAATGGGCTATG CATCTATAGTGAGAGAGGTTCTGCCTAAAACTGTAAGTTTTGCTAAGTAGGGCTCTGAAT TAGGGTCATTGTGGCATATTAGAGGGACAACCAAAAGGCTGGGGGCAAATTAATATACTA AATAAATGTATGGATTTTGTAGTACTTTGTATTTTGTTTAAATAGATTCAGAATCACACT AAGGTTTATCATTTTGAAGTTTGTACCTTTGGTACCTTACTTTTTAAATTTCATCTAGGA GATTTACAGTAATGATTTGTTGTCATCTCATGAATCGTTTCTAAATTTGAGTTTGGGAAT CTTTCTGGTTTCTTAACAATGATCTTTGGCTTGATGTATTTGATGTTTTTGCATTTTATC TTGGCAAAGTATGTTGCGTTAAAATTTGTTTTTTGGCCAATTCAATTCTTTAACCTTTAG GCACTGTTATTCAATTCAACTTGCTTTCCTTTCTAAATAGCCCTTTTAAATTTCTAGGCT TTGTAGTTTACATGATTATAGCTCCTACCTTGCTGCATGAAAAAGGAGAGGAGAAGGCCT TATTTTGCACCACTCGACTCTGCTTCCCTGCTCTTCCAGCCACAGCTGCTTGGGCCAGGA TGTGGGTGCCACATGCAGCAACAAACCTTCTCTATACAGTGTACGTGACCTATGTGGCAT GCTCTGTGAACTCAGCTGAGCCAGACTCATCTCTATTGAGTTAGGAAGCTAAGATCAAGA GTGGGAATGAGAAGAGAATGGGGAGGGTCATGAGGTAGCATGGAGTGAGGGAGAGGCCAG GAGTGGTGCTGTTGATCATGGGAAAGCTGGGGTTAGGAGAGGGAGAAGCTGTGAATAAGT GGTGAAGACCCATCCACGGAGGGAAGCATGAAGCAGAAGACAGAGGGGGAAAAAGATGTT CCAGAGTGAGCGATGCTCCTACTTGGAGTTGGCACAGTTTGGGATGCATCTCAGGTTCTT TTCCTGTTTTTGTTTTGTTTTGTTTAAAGAGATGGGTTTTGCTCTGTTGCCCAGGCTGGA GTGTGGTGGCCTGATCATAGCTCACTACAGCCTAGAACTCCTGGGCTCCAGCCATCCTCC CACCTTAGCCTCCTGAGTAGCTGAGACTATTGACATGCGCCACCACGCCTAGCTTTCAGG TTCTGATCTATAGGTGTCCCTAGAGTCTTCCCCTTCTCCTGATGTAGTTGGGAAACTCTA CAAGGCCTAAATCATGAATTCAACTGTGATGCATAAAAGACATTCAGTTAACTGGGATAA TTGCATAATCCCCTTTTCTTCAAAGGGTTTATGCATTCACATGTTAACAAAATTTGGTGT TTGTAGAGTAGTTTAGCTCCTCAGTGAGTGCCCCAAATTAAGTTATATCTTTAAAGGAGC AGTGCTCTTTATATAAAAGGTATTTCTGTCAAATCTGTCATTTAAAATATGTATACTGCA GCAATACTACGGTAAAATATTAGACCATACTATACCAGTGTATGGTGAACTCTCTCCATA TATTACATATATACTATAAAGTATATATGTTTCTTTTTGCTAGTCAGTTACCAGCATTAT TCAAGAAATAATGGGGTTATTGACGTTAATATGTTAGGTGAAAAAAGTGAGTGCTGTCCT TTTATGTTACTGAGCTTTTATCCTGCATATCAGAATTTCCTTTCTCTTTGTCATTGGCAT TAATATTGTTTTCATCCCTCTTACACTTCTGTGGGAAGTTTGTAGACAGCCAACATGCAG AAAGGTTAGCATGGCAGATAAATATTTTCTATTTTTCTTATTGATAGTTACGGAGAATGC TTTGTTACTCTATGCCTCTCTAAGTAACATGATCCTTGAATAGATGTATTAAATATCCTA GTGTTACTCTCTCATTTTATATGTTTAACAGTTGCGGCTTGTCCCAAACTGGCTCTTTGG CAGGTTTTTTTCTTTCTTTTTTTTTAAATTCATTGGATGTAAATTTCTTCCTAAAAGGAG TTGTCTTTTGGCATTTTAAGTAGTGGAAAAATAAATTTCATTATCTTTCTTCTTTCTTTT TTTTTGTGAAATCAAAATTATCAAGAAATGTGTACATATGGCTTTTCTTCTTAGCATTTG CTACTTTTGTTACTTTTGTCACCCTGGATTATCCAGTTATTCAAATTTTCTGCTTCTCAA TGGGCAAAGTACCGATAAGTAGGGAAGGAGGGAATTTAGCCAAAGTTGTAACTGACAATA AGCAAAATATAGAGGCCTCTGTGTTTCCTGCTTGGTTCTCTTTCTTGAGTTCATCACTAA TTTTATGAAAGAAGAAAACAAAACAGAAAAATAACCAGCTTCAATTTCCACGTGCCTGTT TATTCTGGAGTTACCAGGAAACCTTAATCTCCAGTGAATAAGAACACTTTAAACCCAAAG TTGTTTGGGTTTGTTTTCTTAAATAGAACTTCTTCCTGTTATGTTTTCCTATTGGCATTT GTAAAACAATGATTCATGTGTAAATCAGTAGGAGGTGCTCTTTGAGAAGCTTCCTAGGTT GGTAGGTTCCAGAGCCTAAGCTTTTCTTGGCTTCAGTCAGTATGTTGAGAGGGGAAGGTA TTAACAAGATCAAGGAAGTGATAGTTTTCGGTATGTAGTTGGAAAGTGGGTATGTGTGTC TTCTCATTTGAATATCACTTTGTTGTCCTTTTCATATATTAATATGATGGGCTACCTCAT AATCTGGGAATCCAAAAATTATCCTGCCTTCTTCTAAATTCCATGAGAATACTAAAGAAG AAGTAATTTTAACTTTCAAAGAGCTTTTATTCTGAAGGGAAAAGATGCTTGTAAGATGGT GTTAGCATGCATGTGTGCAGGCTTCACAGAGCTGCTAAGGACGCCATTCATGAGACATTA TTGCCCTCCCTCTGAGCCAGACACTATACCATGTACAGTTCTACAGAGGGGGAAGGGTGG CCCTATGGCTTCTCTCCTCAAGAGGGGCATACTCCAGAGGAGAAGTGGCACAGAAGTGCC ATCCAGTGTGGCGAGAGCTTTACAATGGAGGAAACGGAGGGAGTGATTTTTTTTTTTTTC CCCTATTCTGAGGACTCAGGGAAGATGGATTTCTTGGGAGAAAGTGTTTGAGGTGCGTTT TGAGGACTAGGTAAAAGGAATTTAACTAGTATGTTGGGTGAAGTGAGGAAAGGCTTTGTG GCACAGTTTCTGAGCAGGGGGCAGTTTAGATTAGATTAAGATGCCTTCCAGACCTGTGAC TCCATGACCTGAATGTCCTAATGGAGACAAAATAGGCATTTCCAGCAGAAAGAACCAACT GATTGCCTTTGCAAAGGCAGAATAAAGGACAGAGGAGACTGTTTTTTTCTCATATAGCCC AGAAAACAGATTAAAGGTTTTACATAGATAGATAGATAGATGGATAGATAGATAGATAGA TAGATATCACTTCATCTGAGCTAGTTATTTAAAAATTCTTTAAGTGAAAGGTTTAGAGGA TATGTAGAAGGATTTGAAATCTAAAAGTTAGGAGATCATATTGTTTCTATTCATTATTGA TATGGTTTGGCTGTGTTCCCACCCAAATCTCACCTTGGATTGTAATAATCCCCACGTGTC AAGGGTGGGGCCAGGTGGAGATAACTGAATCATGGGGGATGTTTCCCCTATACTTTTCTT GTGATAGTGAATAAGTCTGGGAGATCTGATGGTTTTTTAAATGGGAGTTCCCCTGCACAA GCCCTGTAAGACATGACTTTGCTCCCCATTTGCCTTCCACCACGATTGTGAGGCCTCTGC AGCCATGTGCAACTGTGAGCCAATTAAACCTCTTTCTTTGATAAATTACCCGGTCTTGGG TATGTGTTTATTAGCAGCATGAGAACAAACTAATACAATTGTCTACTCAAAGAGGATGAG AATTAAAAATGATAGCCAGGGTGACCAAACATTTTGCAGTATAGTTGCTTTGCAGCATCT GACTTCATTAGTGCCAGGTAAGGGACAAATTATTACTTTTTTCCACTACCTTCCTAAATG ATAAATGCATTCCTAGCAAGATTAACTTTTAACTATGCTTTGAAACATGAGTTTTCAGCT ATTGTGATGCCATCATTACATTCTGAATGATAAAATTGCCAAGTTCAGAATGACAGCTGT AAAATAAATGGCATCATTTAATTAAGTTCTGAACTTTTGATGATATGCAGTTTAAAAAAA ATGTATTTTCCAGGAAAACAGTTGGAAGTTTCGACTTTGTGGTTTACTTTTGGCTGTGTT TTATGGAAATCACATGAAAACTTCTGAGAAAAAGAGACAAATGATTCAAATTTTGCAAGT AATAGAAAATTGGGTTCCATTTGTATAAAAGATTCCCTGAAATCATTCACTATCAGTTTA GCACACTCTGGTATTAGCATTTAACCACCAGTATATTGATGAACAAGTACAGAGGAGAAA GCCAAGGATATTTGAGATCCAGTATCATATGCAGAATAAATGTAATAACTTTTAGGGGCG GAATTTCTTTTCTTTTTCTTTTTTTTTTTTCTTTTCTTTTTTTTTTTTTTTTTAGATGGA GTTTTGCTCTCGTTGCCCAAGCTGGAGTGCAATGGCGCAATGTCAGCTCACTGCAACCTC CACCTCCCAGGTTCAAGCAATTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCA CGCCACCACGACTGGCTAATTTTTTGTATTTTTAGTAGAAACAGCATTTCACTATGTTAG CCAGACTGTTCTCAAACTCCTGACCTCAGGTGATCCACCGCCTCGGCCTGCCAAAGTGCT GGGATTACAGGTGTGAGCCACCACGCCTGGCCTAGGGGCAGATTTTCAGTTGAATTATTA ACTGGAATTCATGTTCCTGTTCCCATTTCTCCAGTTCTACCGTCAGCCATTTTAGTGATA GTAAACTCTTAATCTAGAGCACCATTCTTAACCCCAGGTACAGGTTTGTCTGAGGAACTT TTAAAAATTATTGATGCTTTAACTAGAGATTCTGATTTATTTGTTCTGAAAGTAAGGCCT TAGCATTAGTATTTTTTGGAAAAGCTCCTCAGGTGACATTACTCTGTAGCTAAGGTTGGG AACTACTGATGTGCAGTATGGGTAGGTACAAAGAAAAGTTGTAAATTCTTGTTGGTCTCT ACCTCTGATAAAAGGAAAGGAATTACATTTTACTCTTGAACAACACAGTGGCGAGGGTTG CCAGCCCCCACCCCACTGTGCAGTCAAAAATTTGTGTATAATTTTCTCTCCCCAAAAGCT GAACTATTGATAGCCTAGTGTTGACCAGAAGCCTTACTGATAAAATCATCAAATAACATG CATTTTGTATGTTATATATATGGTATAACGTATTCTTACAATAATCTAGAGAAAATAAAA TATTTTTAAGAAAATCGTAAGGAAGAGAAAATACATTAATTATTCATTAAGTGGAAGTGG ATCATCATAAAGGTCTTTATCCTCATCATATTCATGTTGAGTAGGCTGAGAAGGTGGAAA AAGAGGAGAGGTTGGTCTTGTCTCAGGGGTGGCAGAGGCAAAAGAAAATCTGTGGTAGAC CCGTCACAGTTTAAACTCCTGTTGTTCAAGAGTCAACTGTATATGTATTTTGTGTATGTG TGTCAATTACTGATGGATTTAACTTTCTGTTCAGTTTCATTCTCTTAGAGGGTATACTGT GAGATACTAGTTCTGCACTATCTTAATAAATATATGAAAAAAGTTCCATGGTAAGATAAG TTTGAGAAATACAGGCATTTACAGTTAAAAAATAGTTCTTTCCTATAAAACTGGTTGCAA ACTTAAATGTGCTGGTTATTTGCATTTTATGCATTTGTTACAGAAATATGTAATTTGTGG CACTTCCCAGTATTGTTTGATGAAATGATTTCTTTTTCTTGCTAGAAACTCCATTCTACA AAATTAAACAATCAGTGAATCAGTTGGAAATTCATTTTTTTCATTTACTGAGATCTGTGT TAGGAATGGATGTGATGTAGCTATACAACAGAGGCTCTCTTGAAAAGTTCCTCAGTGAGC CTTATCAGAAGGGTGAGAGTGTAAATTATTCCAAGGTACACAATTCTTTTCTAAAAGACA ACTGTTACCTTTTTATATCCATGCTCAGAATTTCTCTGACAACTCACCATTGCCTTCCAG GTAAAATTAAATAAATATCCACCTTTGACATCAAATGTTTATTATAGTCTGATCCCTTCC TACTGATATAACTTTGTTTCCCATTGCCCCTCAACTCAAGCCTTTCTCTTGTCAACCAGT GGTATCCCCAAGCCCTGATCGTTCTTGACTCTAACAGCGATACATAAAAATATATCCCCA ACTAGAACGTCTTTTTTTCCTCTTTGTCTCTGGCCCTCTCCATTAGTTATATATTTAAAA GTCCGTCATTTGGCATTTTCTGGACTAGCCCAGCCTGTGATGACAGTTCCCACTTCTTTA TATGTTAAACTTACATATCTGTGGTCACTTTGTTTGGATTTTCTTAGAAAGTCAATTTTC TTGTTTTGTTCTCTTGTTATGAGTTGATACACTAATAGTCCAACTAGTTTCTGAATCTTG AATTGAGACACTCAAATGTTTTGGGACCTAACACATTGTTCTGTGTATTTGGTGGGGTGA AGTAACTCTGTAGAATTGTGATGTTGTGGGACTGTATGGGACCTTAAAGATTTCCTAGTT TAGCAAGTGTACAAAGGAGGATAAGACCTAGCATTTTTAAGTGATTTATCTGAGTCATAT GACTAGCCATTTGTTGAATCTGGGGAGAAAACCCAATTCAACACTGTTTATTACACTGAC AATTCATAACTTTAAAAAATCTGTGCTCTTTCAAGAGAAATTAAATTTCGTATTTGTCTT TCTTAATGGGAAAACACAGTAAATTAAATATTATTAAAGCAATAAGAGGTAGTGCTATCT TGTCCCATCCTCCTGCCTCCCCACCTCCTCCCCAACACACAAAAAGATCCTATGGGTGTT CTTAAGGAGCTGTTGTCTGAGATAGGGCCTAGGAAGTAGGTTTTTAAAACTTGGGTGATC CAGAGCGGATGATGATATGCATTCTTCCATACACATCATTGTCTCCTCCTCCTCCTCCTC CTTCTCCCTTTTTTCCTTCCCCAATTCATGCCAGGCTGTCATTTTGAATCAATAAGTGAA TGTAACAAATAAGAGATGTTAATACTATGAAGAATACTGAACTAGGAGCCATGAGTTCTG GCTTTGAATTCCAGTACAGTCACCAGCTGTGAAATCTTGGGCAAGTCATTTGACAACTGA GCTTCAGTTCTCCTGCTTAGAAAATGGGGATAATTCCTCATAGAATTGATGTTAAAATTG GTTGAAATATGCACTCAAAAGTGCTTTATAAACAGTAAAGCATTGAGCAAATGCGAGAGA TGATTTGATTCTTTAGAGAAGACCCTTTCATTCTAGTGTTTGCATCCTCTGGCTGGGGGG AAGGCTGTGTGGCTGATGTAGGATGAGGCACCTTCCATATCTTTAGTTGCTTGAAAAAAA CCACACACAGTTCTATAATATTTTTGGCAATTTGTCTCAGTTTAAAGCTGTGATCGTAAC TTTTATTTGGGGATACTACTTTCTTGATTCTTATATGGGGAAAAATTCCATTTGTTGGTT TCCTTTTATTTAAATATGTTTATGTATTTTGCATTTTAGAATAAAAACATTTCCTTCTCG AGTGAAGATTTTTTTTCTTTTCTTTTGAGGTGGTGGTTAAGTTCTCATGTAATAGGATAG TTGGTTGCTATTAGAAATATGTTTTTTCCTTTGTTATGAAATGGAAAATTGTCAGAAACT GATAGGCTGTGGTTAGATGAGGTTTGCTACCAATAAAGAATTATCAGGGTAAACTGAACT TTCATTTAGGATGCAAAAATATTTGTTTTGCTTGGCAGCATGGCATAAAAAGAAAATCCA AGAAACTTCTTGTTTCAGGAGCTGCCAGTTCTCTCTGTGGCTCAAAGAACGTTTCGTGTC TCAGCCACAAGAATTTGCCGCTGGTTCTGATGTTCATTGTCTTCCCTCCTCACGCACGCT TTGCTTTCAGCTTTTGGCTTTACAGCCCTTTGCTATAAGATGATGAAAGTCCTTCCAGGG CTACTCATTAACTTTCCCTTCTACATCTTACTGGTATGAATAGTGGGAGCCTTTCATCTT TATTGTTATGAAAGCTTTTATAGAATATTGAATGCAGGGCACTGTGTTAGAGCTCTGTAA AACATGATAACATAGTAGATTCTGTCAGTTATTGGCTGTGAGTAGAGGTAGTTTGTTGAG GATCAGTATAGGTACCAGTGGCATAACTTATAAATTGGGACAGGCATGGTGGACCAGAGG GGATCTAGTAACTAAGCACTGTGATAGCCAGGGGAATCACTTAAACAGGACCAGTAAGGT ACAGAAGGCCTGGGAATTTGGGGGAGGTATGCGAACAGGAAGATAAAGGGACTGATATTA GGAAATTAGAAGGAAGAATCTTGGATGTAGGATGTAGTGGAATGAAGTGGATTTTAAAGT TTCTAATACTAAATGACAGACATAGTAACATCTAGCAGGAGGGCTGTTTTGGAGGAAAAA AAGAATGTAATTTTAACTAATACGATGACTTTTAAGTCTAGGTGGTAAGGTTTAGAGTAA CAGAGCAGGGCTGGAAATAGTGACTTATTAGGAATTAACTTGCATTCCAGAAATTGAGGG TTCATGTAGAATTGCCTGTAAGCCAGGAGTTTTCTTATTCATCTCTTTAATGTTATAGAA AATAACATCTGTACTTTATGGTAAGTAATTACAGAGTTAAAAAAAAAGGCCATTTGAAAA AAACAGCTTAAAAATGTCAAATAGGAAATGTGGGGATAAGTGTATTCTTTTCAAAATGTG GTTCTGAATTGGACTAACTCAAGCTGCAGTTAAAGGAAAAAAGGCTCGTTTATTTGACTC TTGCCTTCTTTGCTTTCTCCCTGTCTCAGGCTCCTTTCCCCAACGCCTCTCCCCTTTTTG GTCTCAGTGCTTCTGAAATGTAGACACTGGTCTACACATGGGTCACCCAGAGTTCACAGA CTTGAAAGTCCTCTTATTCCCAAGAGCTGTGTGTGCCTCATCAGCCTTCTCTGGGTTTTG TGGCAGGGGGTGATGAGAAAGGATGCCCAGAGGCTACTTGTACCAATAAGAGCCACCGCT TGTTGTGAAAAGAGCACCAATGAGGAGAAAGCAGGCAGAGATAGTCCCGGCACTGGGTAT CTCTTCAAGGCCTCTGGTTCCGTTATTCGTCAAAGGAGGGGTAGAACTAAGCATATGGTC TCTAAAGCTTTGAAATTCTTTTTTCTTTTCTTTTCTTTTCTTTTTTCTCTTCTCTTTTTT CTCTTCTCTTTTTTCTTTTCTTTTCCTTTTTCTTCCCTCCCTCCCTCCCTCGTTTGCTTT CATCTTTTTCTTTCTTGCAGTTGACAAATAAAAATTGTATATATTTATGGTGTACATATT TCATTGTATATATGTACATTGTGGAATAGCTAAATCAAGCTAATTAACGTATGCATTACT TCATATAATTATCTTTTTTGTGGTAAGAACACCTAAAATCTACTCAGCAATTTTCAAGTA TAAAATACATTGTTATTAACTAGTCACCATGTTGTATAATAGATCTCTGAATTATTCCTC CTAACTGAAAATTTTTTTAGTGTGCAGAAGATCCATATCTATACCCTAAGTGTTCCCAAT AAATCAAAATAGTGTCCAAGAAGCAGCTCACAGAGCATATTTGTTTTCAATGTGAGATTT ATGTAGCACTTTTATATTTGCCAAAGCTTTTATTTTCCTAAATTCCCCAGTGAAGTAGGG CAACAAGAAGATCATCAGTGGTGAGTCTGCCATTTAAATTTTTTTTTTTTTTTTTGAGAC AGAGTCTCACACTCACCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTC TGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGTAGCTGGGATTACA GGCGCCTGCCACCACACCCAGCTAATTGTTTTTTTTTTTTTTTTTTTTTGTATTTTTAGT AGCGATGGGGTTTCACCATGTTGGCCAGCCTGGTCTCGAACTCCTGACCTCAGGTGATCC ACCTGCCTTGACCTCCCAAAGTTCTGGAATTACAGGTATGAGCCACTGTGCCCGGCCAAA TTTTTTTTTTTTTTTTTTTTTTTGAGACAGGGTCCTTCGTCTCCCAGGCTGGGGTACATC TTGGCTCAATGAAGCCTCAACCTCCCAGGCTCAAGTGATCCTCCTACCTCAGCCTCCCGA GTAGCTGGGACTAAAGGCATGTGCCACCATGCCTGGCTAATTTTTGTATTTTTTGTAGAG ACAGGGTTTCGCCATGTTGCCCAGACTGGCTGCCATTGAAATTAATCCAGTGTAATCTTC TCAAATGCAGTGTAGTATTGAGAAACGGGGTCCAGTGCAACAAAGAGTTTATGATTTTCC CTGAGCCTCATCCCTAAGATCTTGTTAACCAAATTTTGGACAGAAATGGTAATTTTTCAG TAAGCATAAGATAACATTACTTTTTATTCTTTTTTTTCTGATGGGAGTACTGATCAGTAA ATTAAGCAATATAAGCTTCTTAGAAAAGATTGGGTTGGAAAAAGAATTGAATCCACACTG TAGTTTTGTTCTGGATTTACATTATATGCCCTGCCTGTGTTTACTGACAACATTCCTCGA GCATTTTATTTGCTATTTGGATATAAAAAGGTGTCAGTTGTATAGGAAGAAACCAAAGTT ATAATAGAGTGTTTGTACCAAAATGTTTACCTATAAACAGGTAGGGCTGTCATGAAATGC AATAACTAATCCTTATCCATACTGAAGAAAGCTGCATTGTGGCTTTTTTACATGCAAAGT CTTAAGGTGTTATAACTTAAGTTAGATTTTAAATAAATTATGGACTGCCCTTCTTCCCTT TGTGACCTCTTAAATCTCTGAGACCAAAAATATTTACATATGCAGCTTATAGACATTTGT TAAACCCTAAGATGGTTATTGCAGCCATGGGATACTCAATTAACTGTGCATTTACTCACC AAAAATTGTTTTTGAGCCCACTAGTGTGTGGCAGGTACTGAGTTGGGCCTTTGGAATACA GTGGTGAGCAGTTATGACATGGATTCTGCCATTATGGAGCAAACATAAATTTCACTGAAG AATGCAGACAAAGTATAGAGAAATGAGTAGATAGAATAATTACTGATTATAATGTGTCTA CGAAAGAAACAACTTGGAAGGGACCTATTACATGGTGAACACATCAAGTAAAAAGCTCTT CAATTTTTAAACAAAATAATTTTGAGGGACAGCTAAATTTTCATCACTTGCTTTGGATAG ATAAAAAGCTTTCTTAAGTGTCTATTTCAACTTTCAAAAGCAGTTCTTTGCTTTTCCACT TAGAAAAACACATTTAAAAATTCTTGCCCATTGAGGATATAATTGTATTTTCTTTCAATT GTCTTTATTGGAATTCTTTTACAATTCTTCCAAAACAATAATACATTCCTTAGAGCTGAG CCTCAGCAGGAAAAATGAAGCATCTCATTTGATGTATTATTCCATTACCTATGATGTCAA GGCAGTTGGTAAATAATTTCTTTTTATAGAGCAACCACAGGGGTTGCTAACAGTGCAATC CCCAGGAAATGATTTTGGGAAGCTCTATCATGCGATGGCTGCTATTCATTATCTACTCTG TGTTGGACAGGCTCGGGGTTTTGTTTGCCTTTTAAATCAGGGCAACACTTGCATTGTGGT TTTGCCGTCGTGCCCTTGCTTCATGTTGGAATTTTTCTAGGACTTATTGCAGATTCAGAG GCAGATGTTTGTCTTCCTGAGGTTAGGAGATGATTTGGCGCCATCTAGGTTGACTTCTTT TTTTTCTTTCCTTTTTTTTTTTGCTTTCCTGGAACAAACACTATTACCAAATACATTTCA AGCAATGAAAATAGCTCAGTAGAAATGGTATGGTGGTGCCTTCATACCCTTGGCTATTCG AGTATTGACTAGTCTTAGAGAGATTAATCATTTGTAATTTTAAGTTCTAATAATACAGCG AAGGTTATCATTTGTATTTTAGGAAACTTTATAGCCTCTGTACTTTGTAATGGAGAATGA GTTGGCTGTGGGGTTAACAATGTGGTTATATAGATAAAACCTCTTTTGAGAGATTCTTTT TTCAAGAAATTGTGGTAAAACACACATAAAAGTTACCATTTTAACCATTTTTAAGTATAC AGTCTAGTGGTGTTAGCATTGTTGGGATTCACATTGTGTTAGGAATTCACATTGTGATTC ACATTGTGTTGGAATGTGAATCACAGCAGTATGAATGTACCTAACGTTGCTATTTTGACG TCTAAATGGCCACATGTTTTCAGAGAAAATAATTTAACATTGAAACATAGTTACAAAATA TCTTGCAGGGAAGACACAATTTGAAATTGTAATAGCAGTGCTGCAAGTTTATAGTAAAAC TGGAATAGCCAGGTCTCTTCAAGGCCAGCTTTGCACATTTAAGTGAATAGTAAATAGTTA CTCTAAAGCTGGCATTTAGAATTATTAATTAATTGGTAAGTGCTGAATACCTGGAAAATA GCCCAGGGAAGTATCTGCATTTTGTGAGGTGTGAGTTAGGCTCTGCACTTTCGGGGTGAA TGAAAATGAACAGCAGCTACTCATGGTGGCTTCTTATTCCTGAGTTCCGAAAGAGGCTGG GGGTGTTTTCATGTACTGAGTACTGTCATTATGTAGATCTTAGCTTGTCTTCCCTGAAAT GTTTATTAAATCTCTATGTGTTGTGTTCCAGGGTGTGGAAGAGTGACTTTGGTTGGTTAG AGGAAGAGGTCAGAATGATGAGTTCTAGGTTGGCATTATTCCTGGAATGTCATGGAACTT TTCCTGTAATGAGTTCCTGGTGACTTGAGAACATTTGCAAAACCGTGCCCTCAACGTCTA GCTGTGCAGTCATCCTTTCTGTTCCACTCAGCCAGTGGTCTCCCAGGAAAGTGTGGTTGA CTGTACAACCCATCATTCTATTGCACCAGTCACCAAAAACACATATGCTCCTGACAATAT GAACCATTTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATT ATTGAGGCAGGATCTTGCTCTGCCACCCAGGTTGGAGTGCAGTGATGTGATCACGGCTTA CTGCAGTCTTGACCTCCTGGGCTTAGGCAATTCTCCCCACTCAGCCTCCTGAGTAGCTGG GACTACATGTGTGTGCAACCATGCTCGGCTAATTTTTTTTACTATTTTTGTAGAGATGGG GTCTTTGTTGCCCAGGCCAGTCGCAAACTCCTTGGCTCAAGCAATCCTCCTGCCTCGGCC TCCCAAAGTGCTAGGATTACAGGCATGAGCCACTGCGTCTGGCCCTGTCTTTATTATTCT TGTAAACTTAATGTCTGCAAGGTGTTATTTACCAAAGAGGTTTGTAAACCAGATGTCTCT TCTCTTGAACACTAATGAATAAAATCTTGTATTTTTTGGCTTTCTCAGCTAATCATTACT TAAACCTTCAGCTTAAAAACTGGGGAATTGAAATCCCTGTGGCTGGCTAGTCCTCTGAAG GCTTTGTGATGATGTCACTCTCAGATCGGGACAGAAGCATTCAAGAGAGGGATAATACTC TTGCTTATGTGACAGCTGTATGTGTCCAAGAGCATTTGGCTACATTCAGTGATTTGATGG CCTTGTTCTGATTACAGAGCTCTTTGCTATCTTCTTCCTTTGCATTGAATTTTGTCAAAT TTCCCAGGTATTCTCTGAAGAAAGTTCCTCTTTAGTTGTCAATCACCACCTGTCCATCAG AGAAATCTTTTAGCTACCTCTAAATGTGAGCTTGGCTGGGCTAGGTTGAATGATAGAATT CTTGTATTTTTAGAGTGAATTCTGAATAGCAGAATGGTCAGGACTTACAGTACATTATTT TATCCTTTGTTCCAAAAAGGGGTTTGAAGTGGCTTAACAATTTACATTTAGTAATACAGA CTGAAAAATAAATAGAAGAGGAAATTGTTGTGAAGGGAAAATAAGTGTTGGAAAATAATT TGAGAGGAGGAACAATAAGATTTGTACACAACACACACCAACAGGATCTGAGCTTCCTCC ATGGCCACAGCAGAAAAGGAAGCCTGACCATTTAGGAGAACCACAAGGTCCATGAGATTA AAAATAAATTAGTGGCTCTGGAAGATCACAGGCTTTATTGCTACAGGAACCTTGGAGGAG CTTCTGTTAATTACCTAATGAGACACTGCAGTGTGTGTCTGGCAGAATATGTCCTCAACA GCACCTACCCTGCTGAAATATGGTTGTTTCCTGTTATGTGTCAGTATAGGAAATAATATA GTTTGCTTTCTATTGTGTGCTAATATGACTTAAATCAGTTCTAAAAAAGTTAGAAATTTT TTTGGAATATCTACGATGAGATATATACCTGTCAGTCCTCCATGAATTTCTCCCAGCTGA GTTAGATAAGGTGGTTATCTGGCCTTTAGAATATTATTATTGCTAATAATTATTACAGTA GCACCAGTTACAACACATAGCTACTCTTTCCCAAGTACCTATAATGTTTTAAGCATCATA CTAGGGCACTTGCTACAGAAGAGATCTCTCAATTCTCAGGGAAACCGCGTGGCTTTATTC TTATTTTAGAGAAAGAAAATTGGCTCAAAGACTTTGACTGACTTGGCCAGGTTTGCCTGG CTACCACTCCCTGTGTGCCTGGCCCCGATTCTTCTACCTGAGACCCAGAAGTTGTGTAAG GAAGACAGTTTAGCTCTTTTGAGTCAACTCCCTAAAACAATCGATCCTTTTCTCCTGTTA GTCTGTGCAGCACAGAAACAGAACTCCACCCGTCCCCGTGCCTGGGAAGTCTCTGGTTTT TGTTTAAGGCATGTGTATCCTATACGTGCCTTGTGGCAATTCCACAGCTGGCTCCCTTTA GGCTCCATGGAATTGTACATCTAGGGCCACGTTAGAGTGATCGAAAAAACTAGATAAGGA TAAGTATTTTCTTGTTTTAACTTTTTAAATGTTCTTAAGCTTCGAAAATTGAATTGAATT TAATTTGGCCAACGTTGTCAGGAAGGGCAAGCTTATAAAAAGAAAAAAATAACCTTTCAT GTAAAGTTATTTGAAATCTCATAATATTTCTACTGTGCCTTTTTGATTAAAAATTTAAGT TAAAAGCAGTGATAGATTTTGCCTATCATTTTGATTTTTTAAGTTTATGTTCAAAAGTAT GCCTATATATATTTTAAGTCAGAGCTGGGGTTACTTTTAAATACCGGTTCTTAATAACAA TAAAAGGTCATCAAATAGTATTATGTTCACATTCTAAAAGGTTTAGTCTGTGTCTAAACA AAAAAAATTTTCTTTATATGGACAGAAAGAACTCCCCGCCCCACCAATACACACCCTCTT TCTTACACTTTGTAGTACCCTAGGTCAAAGTAGGGAAGCTCATGATATGTTTTAAAGAGG GAAAAGGTGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGACCGAGG TGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGACTAACTCGGTGAAACTTTGTC TCTATTAAAAATACAAAAAATTAGCTGGGTGTGGTGGTGGGCGCCTGTAGTCCCAGCTAC TCGGGAGGCTGAGGCAGGAGAATGGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGA TCGCGCCACTGCGCTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAA AAAAAAAAAAAAAAAAGAGGGAAAAGGTATGCAATTAGAACCAGATTGGCATTTTGGCAG GTATTTATTTTTCCAGGATGAACGTGCTTTCAAAAATTGCCAGTAGTTGCTAGGCAGACT TCAACAAACACAAAAGACATTTCCCAAGCATCTAACCTGGCTGGTTTCTCCATTTATATT TTGTGATCCTGGCTCGCAGTGTAGTAAACCCTATTACTATTTGAACTCGAAATACAGAAT ACTTCTGCCAGCAGTCCCATTGGCATTTTGCGGCAGTCATGAAGTTAAATTTTCTTCGCC AGGAGGCCAGTTGACTAACTTTAAACGAAGGCACATTGTCCAAGATTGTGGGCAGATCAT TTGAACTGCCTTGAAGTTGAATAGAAACTATATAAAGAAAACAACTCCATCTTGCCAGAA GCAGTTGCCTTTTTATTTGGTGTTCTCCTTTCTGATCACTGAATTTTCCTGCTGAGTTTA TGCTTATTGTATCTTTCTCTTTCCTCTGGCAAATGAACAGAACCCTCACATACGCAGTTA TGGTCAGTCCTTTACTTAAATAACTTTGCTGGATGAATTTGGAACAATGCCAGAGAAACT GAAGAAACCCTTGTTTTTCTGGAATAGCAATTAGATTTGCAATGCTTTTTTTTTTTTTTC CTGAAGAACTGTTTAACCATAGATCTGTCCATTTCCTTATTTTTTGTTTGTTCATTCGTT TTTGTTTTCCACTACTTGTCCAGGCCAGCTTTTCCTAAGAATAGTATTATGCCATTTACT AATAGATGGGAAATGCAGACTAATTTTGAAGGCTAACAGTTTAAAAGTCAGCATCTTTTA AATGCGTTGATCATATTGGGGCAAAGTGCTAATAAATATAATTTTCCTTCCACATAGAGT AAGCATGCACAGCTGGGATAAGATTGCAAAATATTTATCCTGACTTGTAGTGGTAGTAAA TGACCTATTTGTTTGGGCTAAAAGTCTCCATAATATAGTAACAGTTTTACCATATTTTCT AGTAAGTTATGACTATCATATATTCTTTAAAAAAGGTTTTAGGGTCTTGCAGGCTGTCTG CATTGTATTTGGATATTCATTACCTAAAAATGAGGGTATGGATTTCCTTCTGCATGTATA ACCTCTTATTACTATTAACCCTTTATATTTAGTCTCATGTGTCTGGAACATTTTGATTGA GACTAGCATGATATCTCTGTGCCTCCTGTATAGAACTTCTTAGGAAACTCATAGCCGAAA TGACGGGAGAAACAATTTTATTTTAGGCCATGGAGATTCTTGTGAAAAATGTTAACAAGT AGGTAGTGCTGTAGTTGGGAGATATATGTTCTTTCTTTCTTGCCTGTTCCTGATTTTTTT TAAATTAAATACTACAGTCAATTTTAGGGGGTTGACATGCTAGTTTTAAATACAACAGAA GGTATTTCTTTTCGTAGGTTAATATTCTATTTGGAAACATAGCCTTTTTCCTTCTTTCTC TCTTTCTTTCCTTTCTGTTTTTAAGTAAAAATGGTATATACTTATAGAAAGAAAAAAATT ACAGAAAAATCCACAGCAGGAAGTAAAGAACAGCCAAATTCTCTCCCCAAAGATACTGTT ATACATTTTGGAAGCATCTTTCTAATCATCTTCCTATGGTAGATATACCTGCATATACCA CTTTAATTTAATTGTCATTTACTCTGTAAACTAGTCTGTATTCTGTTTTTTTCTAACCAT CAACTTTTCTTGTTCGTAAATACAGATTTACAAAATCCTTTTTAGTTATAGTCTCACATC AAAAAATATCATTGTTTTATTTAGTAAGAAAAGTAGCATTAAACATTCACTATTTGCCTA TAGTAACTATTGAAAACAGAATATTCCAAATTTCTACTGTAAGAAATTTAGTTCATAAAA CATTGAAAGTGTATTATTTTAGGAAAGAGCATGAATGTCAAAATAACTTCGCTGCTTTGG AGAACCAAAAATCTTTGGCCTTTAGCTTATTTCAGAAGTTTGGAAGAACTTAAAGATAAT TCATGAGTTTCAGAAGCATTTTAATACCATAAAATGCTACTTATCTGGAATCCAGAGAAA TGAATCATAGTGGTTACAGTATCAAAGAGTGAGTGATTTTTTTCCCCAAGGTGATTTTTC CACACTCCTAAAAACCATCATCTTCACGATAACCTGTGTCTTTTCACTTGTCAGCACATT GAAATATAAGACTTTTCCAAATCCCAGAACCCTCTTTGGCTGCTCATAGCTACTTTTCAA TCTTTTTGATGGGGTTTAAAGAGCTACCCTGCACCATTGCAAGAATGTGTGCTTAAGGGA TTTGAAGAGGGCTTTCTCAGAAAAAAAAAAAAATGTGTATAATCACGTAAAGGAAGCATG GCTCTGCAAACATGAAACTAGCTGAATTTTTCTCCAGCTTCCTTCAGTGTTTAGCTGTGA CCAGAATTACAGAGAAAGTTGATAAGCATGGTCCATCATCTACTGATTTTGTAAGTGTTG TAAACTGTTGGAGAATACACTGCATTAGTAATGCATTTTCCAGAAACCACATATTTTTTT CTACCTTTATGACATGCTAAGTTATTGTCTTAACTTGATCTGGTGGTTTCTTGCCTTACT TTAATTAGAAAAGATTTTCGGAAATACACATGACACAATCAACTGCATTTAAAAAAAAAT GCTTTGCTTTTCTAGCAGGCCATTAGGCATAAGTAAGGGCAGTGTCTGCTCTTTTGACCA AGACTGTCTCCTCCGGTAGAGCATGGCTGAAGCCGTCTGCTTTAGGAGGGTGTAGTGTTT TGCAGCTGTAGATGCTGTTATATATAAAAATATTTTCACAACTGCCCTCTTTGAACTGTG TTCTCATATGTAACAGATTGTACACAACTCAGTGCTTCACCCTTGTACTGATCCTTCAGT GTTTTTTGTGTTCACCTATGTTAAATGTCATTTCTCTCTGTCCTTTGCCAGAGAGGCTTT TGAATCTAAGCCAAAAAAGGCATTTATTATACACAGAGTTATGTTCTCTGGCATGTAGAA TACTCTTGTATGCTGGCCACTCCACTCGGACTTAGTGTATTCCTATAAATATGTCTGTTG CTTTCAAAGGCTATGATATGGAGGGAACAATGGTATGTTTAGTGCCTCTCTCTCTCTCTT TCTCTCTCTCTTTCTCTCTTACAGAGACACACACAGAGGATCTCATATCTTTAGGCATCA GAACGCTAAGGTACAGAATGCCTCTACACTGTTGGAAATCCTCTCTGTTGTTTGACCATA ATGCTACTTGCTACTCCTGTCTTTTATCTTAATCATGATGACTCCTGATCACTCTGCTTT TCTCTTTCCTTTCTGCTTTTTCATTTTCTCTTGATAGTTGCACTATGCATGTTAGTATCA CATGATTTGAGTAGGACCTTGCTTGTTATCCCATAATTGGCAACTAAGATTCAGAATGGA GAGCCATGTGGCCCTGGCATTCTGAAGAGTGCTTTGAAAGATCTGCCAACACTTGAAGGC ATACACTTCTCCTTCACACTTAATGAGAGGTGGCAGAAACTTCTCTAATAACAACAGCCA CTATTACAAACCACCCTACTACCCTGAACACCTTCTCCCCAATAAGAAGATTAAAGAGAG AAGAAAGAAGTACAAAGTCATTGGTGATAAAAGTGGTGGGAAATGGGTAGGCCCCATAAA GGCGAGTAGATGATCTCTTGGGAGAAAGAACTTTCCAAGGAAATCTCTCTTAAATATTGG GCATGTCTACAAGAGGAGGAGGCCAGAGTTTCTTTCCCTGGTTGCACAACTGCTTAAGTG ACAGACTTGTTGATGTGCCCCAATGCCTATGAAAAGAGACTTGAAGAGAGAATTGGGGAG AAACTCTCCCGCAGTGTAGCATAAGTCAAGTAGGTATCACTGAATGAAGCTGGGCTTGTG CTCTCTCTCTGATAACCCACCCACGAAGCCTGCCTGCTAGGTTAGTAAAGCCCAGCAACT AGAGACCATCAGATATTCTGCTGGTATCAGAGGGTAAGGAGACATGGGAGATACCGATTT TCTCATGTTAGTGAAGTATGCAATGGGAACCCTCATGGGTGTCTTTTAAAAAAAACTCTT CAACTCCCACGAGAGAGCTGCACCTGTGGAGGCTGTCAGCAGCCAGTTAATATTAGAGAA GCACTGGGAAGCAGTGGAAAGAGAATTGTGACTGCATCCAGGTAAGTAAGGAGATATTTG CTTTTTCTTTGATCCCTTTTTCCTCTGAATAGCTAATCTCTATTGGTACTATTCCATGGG CTTTCCAGATATTGGCTCATCTAATCCTTCTAGCAACATGGGATTACATAGGTTCTACTG TTGTTCTTTTGCATGTATAGGAACTAAGGCACAGAAAGGTTTGTTACCTAGGATTTGGAT TCAGGGGGTCTGGCTTCCAAGACCATGCTATCACTACCACATTGTACTTGTACTGCCCTA CCACCCAATATTGAGATAAATCACTTTCAAATATTTTTTTGAATATAACCGTAAGAAATA TATTGACCCACTACTTGACTCACTACGTAGCTACATAAAAATAATGAAACAACATTTCAT GAAACAATACTTATATGTAATATAACCTTATCATTTTGTCTTGTTTTCTCTTACATTAAC GATGCTAGTCACTATCTACTGAAGAGATGATCTGCAGCCCTGAAGAAGTTTGAAAGGAGA AAAGAACAGTGCCATTCCTAATGTATATTTCCTCTCTCTGTCTCTTTCTCCCTGTCTTCT TCCTTTACTCCACTGCCTCCCTTGCAAACCTGAGTTTCCTGAGCTGTTAACTCTAGCTGG TCATGTGGAGTAGGTTAACTTTGAATTAACTGGTTATGAGAGTGGAGTGTTACATTTCAC TGGACTGAGTTTCTGATACTACAAGTGACCAGAACTTTATGGAATCTTACCTTAATGTTA ATACATGAGAAAGAGGGATTCCAGAGAGCACAGTTAAAAACAGTGATGGTGTCCTATCCC CACCAAATGATGATTATTTTAGTGAGCTGGTTGTATCAGCCTTCAACTGTTTGGACTATG TGAGGGGCTTGCAGTCCAGTCAGGATGACCCTGTCTTCAAGGGGTTGTGCCTATCATCCA TGGAACATTGGCTACACTATTCTTATTCATGGCTCAAATGGGGCTGTCAGGATTCTAATT CCAGACCTCAAGCTACTTTGTGTTACTAGCCTAGAGTAGGCTTTACTGAAATAGCTTATT TTGCTAAGTCAGACTTGTTTATTACTGCATTTATTATGTGCAGCACACTCATATTCATTC ATTCCTCCTTGGCTTATAATTTCTTTTCAATAAAACTCAGGCTCCTCGTATCCTTTTTAT AAGCTTTTCAAGTTAACCTGGAGCTCCCCTTGTTAAAAATAAATAAATAAGTCAAAATGA AAAGATGTCTTGGTAGGAGAAGGTGAAACCAACTGCAGTCAGTCTTTGAAAATTTACAAG ACATACAAATGTTAATGGTAACACTTCTGTTAGAGTTTGTGGAATCATGCTTTTTAAAGA CCAAAAAACTACTGGGCTCCCTCCTCACCCCACTCCCAGCTTACAAATTACTTTTGTAGA CGATGAGGAATGCCTGCCCTGAGCACTTTCCAGGCTAAAATGATTGCTACCACGCTCTAA GCTTTGTGACCTTAATTGCCCATTTGTCTGGAAGTTGGAGTAAAGCCAGACTCTTCTCTA AGGGAGATTTTGGCCTTGTTCACAAATACTTCCTCTGCACAGTGAGATGGGTTGTCTGTC TTGGTTTTATTTGGCATGAGGCCATCTGCCTGTGTTGCGAGACAGTGAGCAGAAAAGACC CAGCACACACCACTATTGTGGAGGACATCACCCACCACATCACAGACTGGACTCTATGAA AAACCGCCGGGGAAACTGCCTGCAGATCTTCATACCAGCAGCATCTGTGCTTCCATCCTG AAAGAGTGGTTTGCTTTTTAGCTATGGACAATGTGAATCCTGTTCAGATGTTGTTTCTCT CTTTGCTTGAGGGACATGGGAGTAAAATTTGCAGCCCAAAATAGCGGCCATTCAAGCCCT GTGTAGTGAAATTCAGTGTTCCAATCCTAACCTTTGTTTTATTATTTCCCTATCCTGATT TTCCTTATGAGATTCTCTCAGTTCTTTATTTTATGTTTTTGTTTCTTTTGTGCTTTTTTA GACACCTCCAGTCCTCTTGGTGAAATACATACATCTAGAGTGCTGTTGCCAAGTAAATAC AGTGTGTTTTTAAAGCTTTAGTCTTTTTTAACCTGCTACATAAAATAGTGATTCTATTTG AAAATAAGTTATTTCCCCAAATTTATAGTGGATGACTGAAATCATAACTTTTCTAGAAAT CTTGAGATCTTGTTGTAAGCTTGGCAAAGGTAGACATGATTAAGTAAAAGTGCATCCTTT TCTTGAGATAACAGGATTAAGATGGTTGAAAAGTCATGTTAATTGCTCAATAGACCTTGT TGGTATTAAAATTTATGGAACCACCCAGAGGGCCATTCCAAATTCGGTAATGAACTGAGA TAGAAAGCATATTTAAAGTTCATATTTAATAGTTCAGAAGACAAAAATGGAGTTGGAGGC ATTGATACTGAGAAGCAAGAGACCTATTAGCTGGGTTACTTAGGTCATTTTACCTTTTTT TAAATTGGTCATTTCATCTATAACATGAAGAAACTAGATGAACATAACCAATCTATCATC TCTAGAGTTTTGTGATTTATTTTTCAAATGCAGCTGAAATAGACCCTCAAAAAGAAAATT TACTATTATTGCTTGGATAAGTAAAAATTTGGGAATCCTGAGTTTTGAGGTCCTTAGCGG TAGCCAAATTAATATGTTAATTCACAGACCCTCATTGCTGTCTCTTGGCACAGTGTCTGG GGCTCTAGACACAGTCTTTTGCTCGTAAATCTGAACATATAATAGTAATTTATAATAAAG CAAATTGAAGAAGTTCTGTATACACACACTTGCATGCATGTGTGATTACAGTAGTTACCA GAAAGATTACCTGCTCATAGTTCTCTTCTTGGTAAGTTTTAAAATACCCATCATTAGCAT TCAATAAATATTTATTGTTTTGATTTGAAATTATACATCATTATCCACGTAACACGGTCA ATTATATAATGTCTTGTTGCCTTACCTTGGAATTAATTTTCTTTTAATTTTTTAAGGATG ATAAAATTTTAATATTGTTTACCTCGTTAAACATTTTTGTTTCATGATTTTGGGGGAGGA GATTGTTTAATATTATTACTGTCTAGTGGAATGTGGCTTCTTTTTACTTATTTTAGAACT CTTAAACTTATCTTACACGTGTAATAGAGGAAGGTAAGCACTGCACCTAGCACAGAATTG GAGTTCAGTAAATGTTCTTTTCCTCCTTTCTTTGAATCAGTGTTTGCTGTTAGTAGAAGT CTTCACAGCTAGAAATCTGTACACATGGAGGCTGAGCAGAGGTTTCCTTGATACCATGTT ATATACACTGGAACATTTTGGGCATGCAGGTGAGGGGTTTAATCACCAACGTAAGAGACA TACAGAAAACAAATTAGTACAAAGTTATTACCTTAGAGCTAATCATTGATTTTTTTATGA AGTAAATAAGAGTGTAGTATTTAAAAGTTAAGTTACTCTAAAATATGAAGTATATTTAGC TAGGTTGAATTGATTTTGATGGTTTATGCTGCTGATGGTAGCTGCCATATTTCACAAAAG AGAATGCTTTTTCACTGAGATGGGCAGAAGCAAACACTGCCCTGATTTTGGCCAAGTAAC CAGAAATAGTTTTGGGATTCATGGAGCTGTCTCCAAAATTCCAGAGATATTGCATCATCT TGGTGGGTCTGGTTTGTTTTCAGTTCTTTTAGAAACTGAGCCCTGCTGATGGGACAAATG CTTGATAAATCACATTCACACCAAGACTGTGGACACCAAAGACAGTCACAGAAATTTAAA GCCCATTTCATAAGCATCAAACTGTGCACCCCACTTCTGAAGAGTGGCTTTATTTCAGTG AAAATGTGGTTCAGCATTTCTTCAAAATATGTGAAGTTTGGACTCAAAATAGTTCAACAT GGAAAACTGCTGAAGTGTTGTCTTCATCTGCCATCTGTTCAATCCACACGTCTTGTTTGA ACCAGGGCAGTGCACATCCTTTTACAAGTATTGTTCTTTCTTTTTTTTTTTATTATTATG CTTTAAGTTTTAGGGTACATGTGCACATTGTGCAGTTTAGTTACATATGTATACATGTGC CATGCTGGTGTGCTGCACCCACTAACTCGTCATCTAGCATTAGGTATATCTCCCAATGCT ATCCCTCCCCCCTCCCCCCACCCCACCACAGTCCTCAGAGTGTGATATTCCCCTTCCTGT GTCCATGTGATCTCATTGTTCAATTCCCACCTATGAGTGAGACTATGCGGTGTTTGGTTT TTTGTTCTTGTGATAGTTTATTGAGAATGATGATTTCCAATTTCATCCATGTCCCTACAA AGGACATGAACTCATCATTTTTTATGGCTGCATAGTATTCCATGATGTATATGTGCCACA TTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTG TGAATAATGCCGCAATAAACATACATGTGCATGTGTCTTTATAGCAGCATGATTTATAGT CCTTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAATGGTATTTCTAGTTCTAGAT CCCTGAGGAATTGCCACACTGACTTCCACAATGGTTGAACTAGTTTACAGTACCACCAAC AGTGTGAAAGTGTTCCTGTTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTT TAATGATTGCCATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTT CTCTGATGGCCAGTGATGATGAGCATTTTTTCATGTGTTTTTTGGCTGCATAAATGTCTT CTTTTGAGAAGTGTCTGTTCATGTCCTTCGCCCACTTTTTGATGGGGTCGTTTGTTTTTT TCTTGTAAATTTGTTTGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGTCAGATGAGT AGGTTGCGACAATTTTCTCCCATTTTGTAGGTTGCCTGTTCACTCTGATAGTAGTTTCTT TTGCTGTGCAGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCAATGTTGTCTTTTGTTG CCATTGCTTTTGGTGTTTTAGACATGAAGTCCTTGCCCATGCCTATGTCCTGAATGGTAA TGCCTAGGTTTTCTTCTAGGGTTTTTATGGTTTTAGGTCTAACGTTTAAGTCTTTAATCC ATCTTGAATTGATTTTTGTATAAGGTGTAAGGAAGGGATCCAGTTTCAGCTTTCTCCATA TGGCTAGCCAGTTTTCCCAGCACCATTTATTAAATAGGGAATCCTTTCCCCATTGCTTGT TTTTCTCAGGTTTGTCAAAGATCGGATAGTTGTAGATATGCGGCATTATTTCTGAGGGCT CTGTTCTGTTCCATTGATCTATATCTCTGTTTTGGTACCAGTACCATGCTGTTTTGGTTA CTGTAGCCTTGTAGTATAGTTTGAAGTCAGGTAGTGTGATGCCTCCAGCTTTATTCTTTT GGCTTAAGATTGCCTTGGCGATGCGGGCTCTTTTTTGGTTCCATATGAACTTTAAAGTAG TTTTTTCCAATTCTGTGAAGAAAGTCATTCGTAGCTTTGTGGGGATGGCATTGAATCTGT AAATTACCTTGGGCAGTTTGGCCATTTTCACGATATTGATTCTTCCTACCCATGAGCATG GAATGTTCTTCAATTTGTTTGTATCCTCTTTTATTTCATTGAGCAGTGGTTTGTAGTTCT CCTTGAAGAGGTCCTTCACATCCCTTGTAAGTTGGATTCCTAGGTATTTTATTCTCTTTG AAGCAATTGTGAATGGGAGTTCACTCATGATTTGGCTCTCTGTTTGTCTGTTGTTGGTGT ATAAGAATGCTTGTGATTTTTGTACATTGATTTTGTATCCTGAGACTTTGCTGAAGTTGC TTATCAGCTTAAGGAGATTTTGGGCTGAGACAATGGGGTTTTCTAGATATACAATCATGT CGTCTGCAAACAGGGACAATTTGACTTCCTCTTTTCCTAATTGAATACCCTTTATTTCCT TCTCCTGCCTAATTGCCCTGGCCAGAACTTCCAACACTATGTTGAATAGGAGCGGTGAGA GAGGGCATCCCTGTCTTGTGCCAGTTTTCAAAGGGAATGCTTCCAGTTTTTGCCCATTCA GTATGATATTGGCTGTGGGTTTGTCATAGATAGCTCTTATTATTTTGAAATATGTCCCAT CAATGCCTAATTTATTGAGAGTTTTTAGCATGAAGGGTTGTTGAAAGGAGCTGGTTTTTT GAAAGGATCAACAAAATTGATAGACCGCTAGCAAGACTAATAAAGAAAAAAAGAGAGAAG AATCAAATAGACGCAATAAAAAATGATAAAGGGGATATCACCACCGATCCCACAGAAATA CAGACTACCCATCAGAGAATACTACAGACACCTCTACGCAAATAAACTGGAAAATCTAGA AGAAATGGATAAATTCCTTGACACATACACTCTCCCAAGACTAAACCAGGAAGAAGTTGA ATCTCTGAATAGACCAATAACAGGAGCTGAAATTGTGGCAATAATCAATTGTTTACCAAC CAAAAAGAGTCCAGGACCAGATGGATTCACAGCCGAATTCTATCAGAGGTACAAGGAGGA ACTGGTACCATTCCTTCTGAAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAA CTCATTTTATGAGGCCAGCATCATTCTGATACCAAAGCCAGGCAGAGACACAACCAAAAA AGAGATTTTTAGACCAATATCCTTGATGAACATTGATGCAAAATTCCTCAATAAAATACT GGCAAAATGAATCCAGCAGCACATCAAAAAGCTTATCCACCATGATCAAGTGGGCTTCAT CCCTGGGATGCAAGGCTGGTTCAATATACGCAAATCAATAAATGTAATCCAGCATATAAA CAGAGCCAAAGACAAAAACCACATGATTATCTCAATAGATGCAGAAAAAGCCTTTGACAA AATTCAGCAACCCTTCATGTATTGTTCTTTCTTTGTCCCAGCTTGACCTCAGTAAAAAAT ATCATCCTTTAATCATAGAGGCTCTAATAAGTTCAGTTCTAAAATTTTATTCCCTAAGTT CCTTGATCTGAGAATACAACTCAATTACTTCATGTTTTTACAGCCAGCTGAAAGAATTTA AATGACACCTCCATACTCTACCAGCGGAACTTCCGACCTTCAGTAAATCACAGATGGTTA ATTTTATCTCGGCATAACAGTTTATAATCTTGACAATGTCTCCATGACTTAGAAGGTCAC ACACTGGTTGGACATCTATTAGGAGATTGACAGTGACCCAGTCTGGGATTTGCTTGATTA TTGAGGCACTTCTACCTTCTGCGCTAGCCTCCCTCCAGCCCCATCTTTCTCCATTCCTCT ATCTTAAGTAGGTGCTGTTGTCAAAATGAGCTGCTAGCTTCTCCTCACGTGCGCCATTCC ATCTACCTGAATGCTCTCCTACTATCCCTACTCTTGCCTGGGCGAGATGCATTATTCTTG AAAGGCCAACTCAAATGCCATTTTTTTCCATGAAGTCTTTCTTCATCACAGGGAGCTGGA AATGATCACTGTCTATTGAAATGTTCTGTGTTGTAGTGCACCATCTTCTCACTCATTGGC GTTTTTGTCTGCATGCATCACTGCTCTGCATTATAATAGGTGTGCTATAGTCAGGTAAAG GTAAGGATTGCTGTTTTTGCTTTTTTGTATGTTCCTGAGGAACGTGCACTAGTAGTTTTT GTGTATCTCAGTAGGAGCTCAGTATCATTGAGTGACTGAACATTCCCTTGATTGAACTGG CACCACCTGCAGGTACACTGTGATTGAGAGTAGTAGGAGTGGTCTGGAGCCACTCAAGTT ACCTTAGGGTAGGAAGATTTTTCTGAAAGTGAAATTGTTTTGTTTACATGTTAATTTAAA TTCTTGCTTAGTTAATGTATTTTCAAGATTCAGGATTCAAAATGTACAAAGGGGTATATA TAATGTTAAAAGAGCTTCAGTCTCCTTTCTTTGCCTGGCATGTACTTAACATTTCCACTT TTGAATTTGCTTTTAACTTTTTGAATTTTTGTTAACTTTAACCATAAATCTAGAAACTTA TTCCAATTGATATATAAAGATCACTCATATTTTTTTTTCTTCTTGCTGCATATTACATAT TATTACAATGTGTGGATATAGCGTAAAGAATTCAACCAGTCCCCAGTTGATATGTCTTCA GTTGTACAACTATTTATTGTTAGAGGAGTGAATTTTCAACCATTTGCAAAACTGGAGGAG GATTCTGTACTCTTCTCAGTGTGTCACCTTAGGAAAAATTGTGTCAATCTGTCCTTCCAC TAGTGGTAACTGTGATTACCTAACCAAGTTGGTGAATGATGAGTTTTTTCACTACGACAC CACCATTATCCCCTTTGTAATTAATTAGCACCTTGTGCAGAGATGTTCTCATATTATGCC AATTTCTGTTCATCAAGTCTTCACCTACAAGCCGGAGCTTTCATTAACAGCTCTCTGCTT TTTTTTGAGACAGAGTCTCAGTCTGTCACCCAGGCTGGAGTGCATTGGTGTGATCTCTGT TCACTGCAGCCTCTGCCATCTGAGTTTAAGCGATTCTCCTGCCTTAGCCTCCTGAGTAGG TGGGATTGTAGGTGCACGCCACCAAGTCCAGCTAACTTTTTGTATTTTTAGTAGAGACGG GGTTTCACCATGTTGGCCAGGCTGTTCTCGAACTCCTGATCTCAGTGATCCACCTGCTTG GCTTCCCAAAGTGCTGGGATTAAGGGTATGAGCCACTGCACCCAGCCTCTCTACTTTTTA AATGTAGATTACCACTATGATAGTTGCCAAATGGTGATTAATTTTATTATGCCATCTGTG TTTGTTACTTAGCATTGTATAATAAAGAGCGCTCTTTTATTCCCTGTTTATCAAATTGTT TATTCGTTTAATGGGTTTATGGACTTCCATTTTATTCAGTGGATAAATACTGGATAATGG ATAAATAATATCAGTATTTGATGCCCAAATTGTTCCAAATTTGGCCAGTAGGAGACCTTT CAGGTTGGCTTCTGTGTCCTTTTGACATGCTCCCATCATTCCTGGAGCATTTTCCTGGTT TCTGGCACAAGCAGATGTTCCAGGTTTTTTCTTGTACTTTCTGTGCCCCAGCTCTGATCC TTTTTGTGTAGTGGAGGATGGCAACAAGAAGTCATGATCTGGGCCTCAGTGGGTTAATTG GCACTAGAGTGTAATTGGTTCTGCACCCTCCCAGCAGATAGAACTAGGACATGTATCTGC ATGTGTATGAATGTGTGTATGTATACACGTACGTATATCTATGACTAATTCTATATGTGT CTATATAACTTTTTTAAAAGAGTTCATTCTGGGCTATTAAAAAGTCAAAAAATAACAGAT CTGGTAAGGTTGTTGAAAAAAGGGAACGCTTATACACTGCTGGTGAGAATGTAAATTAGT TCAGCCATTATGGAAAGCAGTTTGGTGATTTTTCAAAGAGCTCAATACCATTCAACCCAG CAATCCCATAATTGGGTATGTACCCGAAGGAATAGAAATCTTTCTACCATAAAGATGCAT ATGTATGTTCATTGTAGCACTATTCACAATAACAAAGACATGGAATCAACCTAAATGTCC ATCAATGGTAGACTGGATAAAGAAAATGTGGTACATATACACCATGGAATACTACACACC CATAAAAAAAGAACAAGATTATATTCTTTGCAGCAACATGGATGGAGCTGGAGGTCATTA TCCTAAGTGAACTAACACAGGAGCAGAAAACCAAACACCATGTATTCTCACTTATAAGTG GGAGCTAAACTTTGAGTACACATGGATGCGGCCTAACTGAGGGTGGAGGGAGGGAGGAGG GTGAGGATCCAAAAACTACCTAATTGGATTCTATGCTTATTACCTGGGTGGTGAACTTAC TGGTACACGGAACGCGCATGACACACAGTTTACCTGTATAACAAACCTGCACATGTACCC CTGAAACCAAGTTAAAAAAAAGACTGTCTTTCAGAATTTCTGGGAAAATTTTATGTCAAG TGACTGATAAAAGTAGAAGCCCAGAAAATAGTAGTTATTGGTGAAAATTTCAGAGAGTAA AATAAAAATCTGAGAAACAGAAGCACTTGAGAAGAAGGTAAAAATATATTATTATAGCAA CAAAGTAACAGTACTAATACTGTTATTATTATTATACTGTGCTGACATGTAGTATTATAT TGTGCTGGCATGGAGGTAGTTTTGTGTGGTTCTTATAAGGAGGATTGTCTAAAAAGGACT CTGAGAGTTCTCTCTGAATTGCCTAAACAATGAGCTAGTTAGCACTGGGGCTTACCCCTT CTCCTAGCAAGAAGAGCTCCTCATTGTCAGCTGCCTGTGGGTCTAGGGGCCCTTTGCTCC AGCAGAAGGTGCTGCAGTGAGCCACAGGACTCCAAATCACCAGGTGCTGAGCAGCTAATA TTCCCAGACAGCCCTTATAAACAGCAGCACCCAAACCTGGAGTACTTGGTGCTCAAGTAG TGTATTTGTCTTCTCCCCGACAACACAGGCAATTAACAAGGCCACCTTCCCTTGTTTGTC AAATAAGGAGAGTATAGTAATAGGGGACACATTTCCTGCCCTAAAATCATTTCTCCAGCA GCATACCCTGGCCCTGGATCACCTCTCCTCAGGAATAATGAGAGATTTCAGGATTGTGTA TCTTCTTTTCTTGCTGTGACTCTTGTTTTATAAATTTCCTGAAAAAAGTTCATTCCTTAA CCCATTAAAAAAAAAAAAGAGTTCATTCTGATAGTTCACATTCTAACCAAATACTTTAGT GTACTTCTAGCCCGTCTCTTCTCAGAAGGTGAGAAAGCTGGTTTCCAGGATCCTCAGTGT ATTAACTTTATGCCTAATTAATTAGTTAATTGTGCTGAACATAACCAGTATTCCAACTAC TCAAGACTCCTTCTGACATCTTTGTACCCTCCCATTACCTCCCTTCCTTGGCTACCAGTC TCATAGGACTGATGCCTCTGCCTGGCAACTCCACCCCATCCCATTGCACCTCCTCAGGAG GAGAGGAGAGAAAAGGGAAAGAGAAAGTCACCCCAGGCGACTTCATGTGCTGCCAAGGTT GAAAGCCACTGTATTTAACATTTACACACATTATGTCTCTTTAAATATTTCAAAGCCTAG ATGCTTTCCACATGGAGTAGTAGAGATTTAAGAAAAGTATATTTTTATCAGCTTCTCTTT TTATAATTTGTCCATTTCTCCCACAAGTGGAATAGAGAGGTAAGTTCTCATTAATTGTGA GGCTGTAGTGGGGTGTTGATGGCTGGATTTTATTCGAATGTTTTCATTTCCTCTGTGGTT TTAGGGCAGTGGTTTTCCAAATGGTCTGATCTAGTGCATTGGTAGCAACCTGATGCTGTC AGGTTTTTTAAGGGGGAAGATTCTTATTTTCAAATTCGTAATTTTTTAAAGGGCTCGCAT ATCGAGCTTGAATTTTTTTTTTTTTTTTTGTCCCTGAAGTTCTCTCATGCCAATCCTTGT TTCTGCTTCTTTGCTCAATTCAGAATACTGGTATTCAGTTAGTTCCATGTCATTTCTCTC TGGAGTTTAGAAATGGCATTTTAAAGGCATCAGGCATCCCCTAGCCTAACCCCACCTCCT TTAGGAAAACTGGAAGGAGAAAAGGTAGAGGGTCACTGGCCTAGATTATAAAAATCAAAG CACCAAACCTGATTATAGTCAAAAGAATCCTAAGAGTGATCTGAAGCTAAATTCCATGGC TGTGTGATTCATGATGATCTAAGACCTTTCATCTGTTTTTCATTTTCTGAAGATTGTTAA GTTGGTTGCTATTATTGACAATGTTTAGGTTTAAACAATTAGAATTAAGGTATAGAGTTA CCTACATATGCTGTGTTCGGGTTGTGCTCATTTGTTGGCACAAGTTGATTCTGCAAAGGT TATGTGGCAAAAGTTTAATTTAGGTCATCTCTTGCATAGTGGAAATAGCTGAAGTCATTG GAGGATAACAGTGCTTTAAGTAAATTTTTACTTAAAAATTTGATTAAGTATTATTGAATT TATACTTCAAATCTGATATAATTTGGCTTTTAACATATGAGGCATTGAAATTTGGTATAG TTTTAAAAGATGAAATCAAGAAAGTAAAATCAGAAAAATTCGAGTGTAGGTTGAGAAAAA ATTGGAAAAATATAGAAAACTATACTTTTTAACCTTAGAACTGTCACATTTTGGAATTTA AAAATTGTTATGAAGAATAAAATGTTCCATCTCTTATGTTCTAAATTTCCATGTATTGTG TTTTCTCTGCAGTGAGGTCCTTTGAGAGGCACATATGGGCGTGCAGTTCCATTCTCTTAG TGTGTGCCTGTGTATTGAGTAGCACCTGCCTCTGGTGTACTTGAAGAAAACTTAAGTGGC TATAGAATTAGTAGTCCCTCCAGGCCAAAATACAAATGACACATATCTTGGACATCTTCT ACTAGAAGAATATAAAAATCCCAATGGCCTTTAAAAAATTAGAATAATGTTAAAAAACAC AATTTATAATTTCGTTTCTAAAATTATCTGAAGGAATTGGAAGGATATTCCATTTTTAAA TGCCCAAATGAAATAATCCTTTTAAACAAGGGTTTTCCACCCATGATGAAGGAGGTTAAA TTAAAAACTTAACTAAAATGAGAACAATTGTGTTGTTCTTTAGTTCTTGCATTAGGAATG TGAAACCAGAAGTCAGCTAAGTCTCCATAGCAAGCATCTGTATTTACAAGATGAGTAACA CAAGTCTGAATGTTGCGAAAGCTCTCGAAAGGTGAAAAAAGTTCAGAATATCAGACGTTT TGACTAGAAACTCTGTCACTGATTATCTCGTATTACAATGAGAAGGGCATGACATGACCC CTGATTACTTTTACACCTTTCTTGCTTCTGAATCCTTGTTTTTGAAACATAGGAAAGAAC TATTTTGTTGACAACATTGCAGTTTCATATAGTTCATCCTAATAAATGTATAACAAAACT ATCATGAGATAATATAGGAGATTTTGTAACAATCTGGTAAGAAAGGAAAAGTATTGCGAG TTCTGAACATTCAGTTACATGTGGAAAACTTGTATAAAGTGAATTTATTGCATTTGTTGT CATCACTTTTCTGAAAAAGAGAACTCTTGCAACTAAAATAAAATTCTTTTTTATCCAGTG TCTAGAATAGTACCTGCCACACTGTAGGCACTCAATAATGTTTTGTTGAATAAATAAATG AAAGATGTCATTTTTATTTGTAGTTGGCTTTGAACATCCAATTTTTTTCTTTTTCTTTTT CTTTTTCTTTTTTTTTTTTTTTTTTGAGACGGAGTCTTACTCTGTTGCCCAGGCTGCAGT GCAGTGGCACTATCTCGGCTCACTGCAACCTTTGCTTCCTGGGTTGACGCCATTCTCCTG CCTCAGCCTCCTGAGTAGCTGGGACTTCATGTTCATGCCACCATACCTGGCTAATTTTTT TATTTTTAGTAGAGACAGGGTTTCACCATGTTGACCAGGCTGGTCTCGAACTCCTGTCCT CAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGGTTACAGGTGTGAATCACCACA TCCGGCCCAATTTTTAGGTTTTATTTAACAGACATTTTCTTCCTCCCAACTTCTAGCACT GGACAACCTCTGGTGTGTTTTCTCTTTCTTTTCCAACATGTCATTTAAATCAGGGGTCCC CAGCCCCCAGGCTGTGCACTGGTATCGGCCTGTTAGGAATTGGGTCACACAGCAGGAGGT GAGCGGTAGCCAAGTGAGCATTACTGCCTGAGCTCCCCTTCCTGTCAGATCAGCGGCAGC ATTAGATTCTCATAGGAGCATGAACCCTATTGTGAACTGTGCATTCAAGGGATCTAGGTT ATGCACTCCTTATGAGAATCTAATGCCTGATGATCTGCGGTGGGACAGTTTCATCCCGAA ACCATCTCCCTGCCCCTGCATTCGGTGAAAAAATTGTCTTCCATGAAACTGGTCCCTGAT GCCAAAAAGGTTGGAGATGGTTGGTTTAAATAGAATCATATGCTATAGTCTTTTGTCTTC TTTTATTTATTAAATCCTTTGAGATTCATCTCATTTGAGGTTGTTGGGTGTGTCAGTAGT TCATTGCTTTGGTTCTGAGTAGTGGTCTATTGTATGGGTATATCACATTAAAAACATTCA TTCACTAGTTGATGGAATTTGAGTCATTTTTAATTTAAGGCTTTTATGAATGAAGGTGCT GTAAAATGCACATAGAGGTCTTTGTGTAAACATATATTTTCACTTCTTTTGTATGAGTGC CTTGGAGTGTAATTGTTGGCTCATGTAAGTGTGTGTTTCACTTTCTAAGAAAGTGCCAGA TTATTTTCTAAAGTAGCTATGCCATTTCAAATTCCCACCAGCAATATAGGAGAGTTTTAG TTGTTTCACATCCTTGTCAGCACCTGTTATTATCTATCTTTTGAAATGTTAGTCATTCTG GTGGATACTTAGTAGTTTCTGATTGTGGACTTATTTGCATTTCTCTGAGAACCAATATCG AGCATTTTTTAATGTGCTTAATCATTGTTTCCTTTGGTGAAGTATATGTTTGAGATTTTG CTAATTTTTTATTGGATTAAAAAGCATTAAGAGTTCTGGATATAGGTTCTTCATAAGATA TAGGTTTTGTAAATAGCTTTTTCCTCAGTCTGTGGCTTTGTTCTGCATTTCAGACATTTT TCATTGGATTATTTTATAGTTTTTATGTCTCTGGTAAAATTTCCCTTTCTATACAGACAC ATTGATAATATTTTTCATTAGATCCTTATATTAATTGTAGTTATTTTAAAAGTTCTATCT GATATTTACAAGTCTGGGCCATCTTGAGGTCTATTTCATTTGACTATGCTATCTGTTGAT GATAGGCTTGTGGGTTTTTTTTTTCCCTCCACTTTTGTGTCTTGTAATTTTTTATTGAAT ATTGGTATTGTGTGTTAAAGAGCAATAGTCTGTGGTAAATAAAATTAATACCCACAATGG TTACTTTTTTTGTTTCTTCAGTTCGTTAATATAGGGGAGTGTGTCAGTAGTCAGTATTGT CAGCAGTTGAGCTGGGTTTGAATTTTGCTGTTGCTGTAGTTACCTTGAGTGCAAACAGAC TTCAGATTTCTCCAGTGGTGGATGGATTGCTGCTGCTACATTGAGCTTAATATGAGTCCC GGAGTGTGGTACAGTTTTCTGTGTTCCTGATCTACCTTTGGCTTTCTGCCAGCTCTGTAC AGCTGTGCCACAGGGGTCTGTGTTATTGCCACTTCCCCAGTAGTAGACTACTGCTTGTTA TTACTTGGTAAAAAGTTCATGGAAGGGTAAGTGGGTGGTTTGGTAGTCTGTCACTTCCCA GCCTCAGTTTTAGTCAGGTCTTGTGTGCCGAAGCCTCAGGAAAGGGGCATTCTCAGTGTT CCCACCTCTCTCAAAAACAACCATTTTTGAAATCTGCAAGATCAATTTTAATAGTATCTT GTTCCCTTAACATACTTTTGATAACTTCTCTTGTGTTTTTAAGCATAAGTATTCTGTATA ATATTATTATAGTGCCTGCATTATTTTAGTGGTCTTTTTCTGTTGACTCTCACTAATCAT GGCTTTTCCTCTCATATCTTTGGTGGTTTGATTGTACTTGTTGAAGCCCGTATTTAAACT CCTTGGCCTCAGAGAGTATTTTTGTCTTTATCTGCCTGGGAATACAGCCATAACTAAATG AATCTGTTTTGCTTTGTTCATGAATTCTATCGCCAATAGTGCATAAATACAATCTTGTGT TTAGGAATTCAGAGGAGAGAGGTTTTTCATTCCCCTTGCTTCACCAAGGCAAAACCAGGC ACTCATCTACACTGTGAATCACTAAGGGAAAGTTTTATTTTATTTCATCTTCTGAGACTT TATGTGTTTTGATCTGAAATTTATTTTCTATTCTTTAAACATTTTTTAAAACCCACGCTG TAGACCACCAGGTATTAGTGGACATTTTGCTGGCAAATGCTGGCTCTAGCCCTAATTTAC CCGTCTATTTCTTTGTTATCATTTCTGATCTCTAATGAATTTTATAACCTTGCAAAAGTA TGGTTTTATATTTTACTCAGCATTTTGAGATATTTTCTGTTTAAACATGTATAGTCGGTT TCATCTGAACATCCAGTTTACCCTCTTGCTAGACGTACAAGTTCCTTATGTTCTCATACT TCTGGCCAAGCAGTTGATATATTATATTGGTAAAATAAAAACTTCAGCCAAATTAAATTT AAAGGAGCTTAATTGAGCAATGAATGATTTGCAAATCGGGCAGTCCCCAGAATCACAGCA GATTCAGAGACTCCAGGGGTGCCTTGTGGTCAGAACAAATTTATAGACAAAAAAACGTAA AATGACCTACTTTCACTTTCAGAAGTGAGGTGCAGAAAGAGTGAGATTGGTTACAGCTCG GCATTTGCCTTGTTTGAACACAGGTTGAACATTCAGCAGACTGTGAGTGGTTGAAGTAGG CCACTGAGATTGGCCAACACTCAGCTATTGTTTCAGGTGCATATTACTAAGTTAGGTTTT CAATTTTGTCTCACTGTTAAGCTAGGTTATAGTTCATCTATAAGGACTCAAATATAGAAG TACTGAGTCCTTCTCAGGCCATATTTAGTTTGCTTTAACAATATCCTAATTATGTTCTTT TCCTTCAGCCAGCATTTTAATTCTAATAGGTTGCTGAATGTGACTTTTAATTTTTGAATC CTTATCCAAGCACACAGAAGGTGGGAAGAAGTGTGATGTAGTATAAAAGTGCTTGGATTT TTCATTCAAGTGTATATATGCTGGAAATACAAAATCAGCATTTATTAGCTGTATGCTCTT GGGCAAGTTACTTAGTGTTTGAATCTCTTTCTTCACCTGTTAAATGGAATAGTGAGGCCT TCCTTTTATGGGACTAAAGACAGAAAACCAATCTACCTAAAACCTCCTACCTTGCATGAC CCCTCCCACCATGCATAGTAGCCATTCAATTGCTGATATGGCACTCTTTTTCTCTTTCTT AATTGAATTATTTAGGATATACTTGTTTTTTCCTTGAGTTCCTCCCTGGAAACAACTTTA AATAAGATACTAAAAAATTTCAGCTATTTGCTCCTATTTAACTTGTCTACTTAATATTTA AATTCCTTTGATAAATATATTAGACATAATGGGTTATTCTCACTTTTCAATAATGATCTA GATGAAAGAGGCTTACAATTTGGTCAGCTAGAAGGAAAAAATTTCAATTTAGTGCCACTG ACAGTTTTAAGGAAGGCAAATTACTTACCAAACTAGGATTTCATTTTATTTTCAAACTAA TTACTGTGTGTTTGTACCTCTGTAGATTATATAAGTAGGCTCCAGAAGAAACTACTTGCT TATTCTTCTTGGCCTTTTAGTCCTTTTAAAAGCTAATTTGTAAAGAATGACATGTAAGTT TAGATATACAATTTCTCATAGCTATTAATGATATTTCTTTACCAAACTATGAGAACACAG TAATGATTTTTTAAAGTGAAGGTATGAGGTATTTGAGGGAATTTTATGAAGTCTGGTCCC ATTTGTTCACTGGAATTATGAAAAAAATATAGCAAAAGTAGAAGTCTTTGGATACTCTTA TAATTCTTAGGGAAGGTAGTTTTAACCTTAATTCTCAGGGTTCAAGGAATTCTTATATTT CCCTTTCAAAGGTCTGGATGGTGTTACCAATACCAAAACACACTTTTAAGTACTCTTTTT TTTTGGCAGCTCCTTTTTTCTTAAACCATTCTGTGGAATTAGTAAAGAACAGTGAAATTG GATAAAGGCAAAGGCAATAGGGTAGAGGGGAGGAAGTAAGCCTGAACATCTATTACCAGT CTCTGAAAGATCAAATTTACCTTTTAAAGTAACTACAGGGTTCACTTGAGTCTATTTATT TTGTCTATGAGGAAATAGAGTGTCAGAGAGATGACATATCTATATGAACTAATAGCTACT CCTTGGAGAAGCCAGGACTGGAGGATGCTCCTAACTCATAGCTAGGTGATCTTAAATCTC TCTAAACTTCCTTTTCAAATGTTAAATGGGGAGCATGCCTGCTTAATCAGGTTAAGTAGA TTAAGCAGAGGTAAAGCACATATTTATGAAGTGTTCATGGATACCAGATGTTCAATAAAA GTTTTTTTCCTTTGTCTCATCTTGGCTTACTGTAAATTTTTTAAAAAACATAATAAATTA AAAATTGGTAGTAAACAGTTTACACAGAATGAAATATTTCACGGTCATCCGGCTTTTAAG AAAATGCATAGCATGCAAACTGGAAGCAAAAGTTCTTTGGGAAGAGTCCTTGAGTCATTT GAATTTGGAAAGGAAAGGAAGTTTTACGTCATCTGTAGATGCTCTGATTTCAGTTGGTGC ATTATTGCCTTGGGCCAGGTGCACCAATTTATACAAAAAGTAGTTTTAAAAACTTTTCCT CTCCATTTCTTTTATGAATTCATCTTGTGTGAGCTTTTGATCCTCACTGAATGACCTTAT AAAATAAAGGGAAAAATCAATAAAGCTTAAAACTTATACTTTTCACTCAATTTTTTTTTC CAGATGAATTCACAGTGCTCTGAATCTCACCTTTAGGTTTGACCCTGACTGAAAAACATC TCAAAATTTTACTTTTGCACAACAACCTGTATCCCAGTAATCATATTTGAGCTGCACTTT TACTTCATTTGCCCTTTTAAAGAACACACATTGCAAGGATTGCATCAATTTAAATGGACA TAGCATGTGACTAGAAATTATCTTATTTGGGAAAAGTGTTTTATTGATAACAGAGAGTTC TGGTGTTGGTTTACTCATTTGTTGATGATCGTTACTTCATTTTGGGCCAGTTACAGTAAA CCAGAACCTAGGAACTTGCAAAGCCAGATTATTTTTCCTTCTCTTCTACTAATGGTGCAT CTAGTTCAGTATTTTTCCTGATCAGATTAAAGAAAAACTTAGAAACTCAGGAGTTGGGAC CAGCCTTGAGCTCACTTAGCTTTTTCTCCCTACCATCCAGCCCCACTCTGTCTTTAACAG TGGGAATCTAACAAGAAATAGTGCCTATTTGAGGGATGTTTATTTGAAGGATTAATAAAC ATTTATTTTGAAATCTAAAAGGATTGTAAAAAGTTTTTGAGCAGTTAAAGCCCATGTTTT TACTGTAGTTTGTATAGTAAGAGAAACTAATATCTAAGAATATTTCCCAGATTATTTGTT AAGAATAAAACCTTATCTACTGAAAATAAGCAATAAAATATAGTTTCTTAGGTAGTGTAT ATGAATAGGCAATTAAAATACTTGTGCTACTAAATGACAGTTCTTTTTTTTTTAAATATA CCCAGTTGAGCATCTCAAACCTCAATCCAAAATGCTCCAATGAGCATTTCCTTTGAGCCT CATGTAAGCGCACAAAAAGTTTTGGGTTCCAAAGGATTTTGGATTTTGGATTTTGGACAC TTAACCTGATACGTATACAGGAATGCTTGCCATTTAATAAACTCTATGTATTGGTTGAGA ATGATGAGAGTCTATTTGGAGCATCTGAATTTGTAGTTGGTTTTGAAAATTCAAATTATG AGTTTTAATTAAAAGGACAATTTGACCCTTATATTTTGAAGATGAATTTTTAGTAAAATT TAACTAAGCTTTTAATAAATTGTAGTTGCTAATTTTTGCAAAGAAAGACCTGGGGTGTTT TTATGTACAAACTATTGTATTTGATAGTGGAAATTAAGGCTAGAAACAATATTCCTAGGG AAACATGCAAAAATACGTTGAGTAACATAATGTGACATTTGAGATGCCAGTGATAGTTAT CTACTATAAAATAGGTCCCACATAGCTGCCAGAGTATAAAAATAACAAAACAGAATCCCT TAAAACGTTACATAATTCAGAATAACTGTTATTTTCCCTAATGAGCTAGAACTTTACCCA TATATTTTTTTCTGAATTAACATGGTGTTAAAATATTTCTGTTTCACTCTTTTGCTGCAA AGTAAATGTTTTGGGCTTTTGATAATGATTTCAAACGGCATTAAAATTCTTTGTCATTGC ATTGCTCACAAATCCATTAGTAGTAAACATTCATGAATTCTTAATAAAAGTGAAGATGTG AAGGAAAGGAAGAAGAATGTGCTCTGTTTATGTTATTGTAAAGTTTTAGATCGTGCTTTT AAAGAAATGCAGCTTGGTTAAAGTTTTTTTAACATTCTAATGGGAAAATGCACAAAAGTT GAGATAATTTTGCATGGAATACCAGATATCCACTACCTAAATTCTAAAATTATTTTTAAA AATATTTGCTTTATCACATATCCAATCTTCTATCTGTTCATCAATCCATCTTATTTTTTG ATGCATTTCAAACTAATGCGCAGAAATATCCCTACACTTCACCTCATCAGCGTGCATACC AATTACTAGTGTCAATATTTCTTACATAGCTTTTTTGGGGGTGGTTGTTGTTAAACATTC ATAAAGTAAATGTAGCATTCAATGTGTTTCTACAAATGTATATATCTATTTCACCCAAAC TCCTATGACGATATAGACCATTATTATCACATTATCATCCTACGCCTTCCAAAAAACTCC ACTGAATATCCTGTCCCCATCTGCCATGGCAACAAAAATACCCCTATGGCACTAGGGCAA AGTGAGTAAATGTGAAGAAGAGAATACTGGCAGGACTTTGGGTCTGATCACATGGGAGGA GTCAGGGACAGGCAGTGGTCAAGGATGACACTGAAGACTGTGACTTGAACAGTAGAGGGA ATGGCAGTGCCATTTACTGAAATAAAGACTTGTGGAAAAGATATACATTTAGATGAGCTC AATTTTGAACATTCTGATTTTTAAGTTCCTGTGAGATCATCAAATGGAAATACCTAGCAA GTAAAAGACTTGTTTTTGGCATCTTTATTCATGAAAGCCAAAAACTGAAAGCATCCAGGT GTCCATAGAGTGGATAAACAAACTGGTGGGTTTCATACAATGTAACCATACTCATTAATA AAAAGGAAGGACCTACTGACACATGCAACAATATGGATGAAACCTGAAAAAGCGTTATGC TGGGTGAAAGAAGCCTCACCCCATAGAGCAGGCACTGTATGTTTCCATTTATATGATATT CTAGAACAAGCAAAACATGGCTCTACGTGGTTTGCCTTCTCTCTCGTCTTCCCTTTTTCT TGTCTTTCTAACCACATGGTTTTGCATGACCCTCGTCCTTCCCATGTAAGGCGGTTTCCC TCTGCCTTGTCTCTTTAATGAGATCATTCCCATTTCTACAGAGTCATATTCTAGTGTCTC CAAGAAAACCTTCTTATATTAGTTGGGATTAGAATTGTCTGCAGACATAGAAAACCAAAG CAAAACAAAATAACCATTGTTTAAATAAGTTGGAAGGGTATTTGTTATGAAAAAACTCTG TAGCAAGGTAGTCCAGGTCTGGTGTGGTGGCTGTTTTCCAGAGACCTCAGTAACCCAAGA TTCTTCCACCTTTACTGTTCCCATCTGGAGGGTATGGCCCTTATCTTCATAATCCAAGTT GGAACTGTGGATATCACAGTCCAGTTGGCAGGCTGGAGGGAGACACAAAAGACATTGACA AGCTGAATGATGAGATTTCTTAGAATCTGCTAAAATTTCCCTGGACAGAACTTAGTTATG TGCCTTGGGTGTTACCTGTCTTCAAGGAAGGCAGGGTACTTAAGTGTCCATGTGTCCAGC TAAAAATGGGGTTCCAATTGGGACAAATTGGAAATTAGGGTGGGCTGCTTAACTACTTCC ATGCTTCCCTTGATTTCACATTATCCTCCAGCCATTGTCCTGTTTCTCTGCTGCTTGTTA GAATTGATACTTCTTGAAAGAGTTATCTACTCATAACATTCTATTATACTTCCCAAATTG CCTTGTTTTTTCAACTCACTCCAGCTTCTGCACTCACTCTTCCATGTAAATGGCTATCAA GGGTACCCATGATCTGTTTCAAAATGTAAGAGATACTTTAAAGTTCTCATCTTATTTGGT TTCTCATCAGCATTCAATTCTTTTCCTTTTCTTGAGATTCCCTGTAAAAGGAACAGCCTC GAGTTTTTCATTTGTCGTCTATGACTTTGTTGTTGTCTACCACCATTCTGGAAGCTCGTT CCCTGTCATTTTTCTAGCATTTCCTGTTCTGTGCAGTGTCTAAATGTTGGAATTTTTTAA GGTTTAGTTTTTATTGTGGTAGCATATACATAACATGAAATTTACCATTTTAACCATTTT AAAGTGTACATTTCAGTGGCATTGAGTATATTCACATTGTTGTGCAACCATCATCACCAT CCATCTCCAGAACTTTTTCATTATCCACAACTGAAATTCCATACCCATTTAACAATAATC ACCCATTTCTCCCTCCTCCCAGTCCCTAGCAACCACCATTCTACTTTCTTCTCTCTCATT CAGACTTACTGGAGTAAGTCTCTCAGTAGATTTACTTTTTAAATTCTATTCACTATTATA TACCTAATGCTTAACATAAGGACGGGCACTTATTTAGTATGCAGTAGATGTTTGTGAATT GAGTGAATGCTAATCTCCCTGGCATGTTTTGTGTTACCCCATTTGATGGAACCATGCTTC ATATTGCAGCTTAGAAAAGGTAGCCTTTTCTGATTATTAGACTAGTTGGGGTCTGTATGT CAGATGATATCATTGCACTTTGTAAATTTTTCATGACACTTAACTTTGTAATTATATATC GGCAAGTGGTGTTTGACAGTTTGTTTCCCTGTATGTACTATAAGCCTCACAAGAGCAGGG ACCAAGGCTGTCTTGGCCACCATCCTTTCCCCGGTGGGAAATATAGTCTCACACTCACCT TGTTTTATAAATGAATGCTCAGTGATAAAAATAAACCTCTTTAACTGGTTACATTTCCTA ATACCTGAAAACTGTATGCCATTTTATTCTTTGTGACTAGGTGTTGGAAATTGAGGTTAT ATTGAGGGAATTTGAATTTCTTGAAACCAGAGTTTGGAAAGTTTAGTGGTTTTTAATTGG ATCCTCTTTAAATGTTGAGAAGCTAAAGATTCACCAGGGGAAAGCCATTTTGAAACTTTT ACTATAAGAATCACATGAAGAGGTCTGATATATTGCCAAATCTAATTCTGCACTGTTGCA GATGAATGCAATCTTAGGACATCTGTGTGTTTGTCTTTCTAGCTCTCCCTTGTGACATCA TTAGTGCACTTAAGCCTCCAGAGTAGCTTCTTTGGAAATTTTCATTACCAATTAAACTCA TTTTTGAAATGTATAAATTCTTTGAATATTACTAATAACTTTTTATAGGCTCCACATTTT TTTCCTATATCAGGAAGATTTAAAATTACTTTTGCAGAAACATACATGTAGAGTGCAGTA GGTATTTTCTACCATGCTGTACCAAATTCAATAGGGTAACAATTTTTCTGGCATCCTCTG GGAAGGAATCAGTTCCAATATTTATTCAGGAAGTATTATTGAATTCCTACCATGTGCAAG GGGATTTACATATAACCCTTGCCTTAGGCTTAATTGGACTCAGTTTTCTAGCAGCCTTTA GCCCTGTGCCTCCCCACCAAATGCTTTAGCCTGTAAGACAGGTGCTGGACTATAAAGCTG TCTGTTCCTTCTTCCTAAGATCAAAATCCAGCTAGTTATAAAATGCCGTGGAGCACAAGC TTTTATGATTCTGGTAGTAGCACCATCTACTCACTTTGAGTATTACCACATTCTTGTTAT TTTTTTCATTTTTATTTTTTGTGATTGAGTCTCCCTGTGTCACACAGGCTGGAGTGCAGT GGCACGATCTTAGCTCACTGCAACCTCCACCCCCTGGGTTCAAGCGATTCTCCTGCCTCA GCTTCCCCGAGTAGCTGGGACTACAGGTGTGTGCTACCACGCCCAGCTTTTTTTTTTTTT TTGTATTTTTAGTAGAGACGAGGTTTCACCATGTTGAGCTAGGCTGGTCTCGAACTCTTG ACCTCAGGTGATCCGTCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCAC CATGCCCAGCCTATTTTTCTTTTAATCTATCTCAGGTAAACACTCAAGCTAATAGCTTGC TGGTTGTATTTGTCATACAAGTTATGTTCACTGTAGGCCATATTGTGTTTGTCTGAATAA TGGTTTTGAAATAAATCATTTAGCTACCAACATTTTAGAATTAAGGAGATTTACATACCA ATTTGGTTTTGTAGCTTCTCTTGGAAAATCTGAATGTCTGGCTATTTTGTGCCAGCATTT GCACGTGATAGCTGGAGCTGGTGTTTGCAAGCTTAGGCAGGGACAGTCCCTATCCTATTT GCTGCACCTCTGACCACTCTTTATTATTTCCCTGAAACTCAGATCAAGTGTCAGTTACCA TTTATCCTTGTCATTGTACTATTGGTTTTTTTTTTTCGTGGTAGAGTGAAATAATTTTTG TACCATGTCTGCAGGTCAAGGGGAAATATTAGTGAAGGGGTGTTAGTGAATGCCAAGAAA ATGAGACAATATATTTCTTTGGGCAAATGAGTAATTTTCCTGTGTCTGTGTTTTTCTTTT GTGGAACATATATTTATGTTAAAACCATGCACTTCTGCCCATTCATTCCTCACTGTTCTT TCTCTGGCTTTTCTAGACATCTGAGTCAGGCACTCTTGATTAGATGCATGATTGTACAAA AGGAAAGTGATTCTACCTGAGGGCCGCTTGAAGGACCAATTCAAATAGAGTAGTAATACA TCATAACTATCATAAGAGGTGATATAGCAGCTCAGAGGAAGGAGAGATTACGGGAATCTT GATGTTGCTTTTATAGTTGCTGTTGAACAACATGTAGAAATTCAGCAGCAGGAGACAGTG GGACAAAAGGACAGTTTGAATAAAGCAAAAAAAGAAAAAAGGAGGATTGGGTGAGGATAG GACAGTGGCTAGTTATAAGTAGGGAGCTCTGAGAGAAGTAAAACTTAAGAGGCTGGTTGT GGCCTGGTTATGGATAGTCTTAAATGTTAGGCTGAGAGACAGATAACAGTTAACCTCTGA GAGATGTTGTAATTAGGGGAGGGAAATATCAAATTAACGACTTGTATGAGAAAAGGCTGG ATGTGCCACCATCAAGCATGAAATCCTCTGTGTAAGTACTCACGGATGGTAATTATCTGG ATAGAAGATTGTCTTGGATTATGGACATGGTTTTGGAGAGGGAATTGCTAGGTCTGTGCA ACTTATTAGATATGGTTGTGGTGGGGGTTGAGGACAGTTGGAGGAGAAGCTGGGAGAGAG GAGAGAACAAGGATTTGAACACAGATATCTGAGGAGAGCATGGAAATCAAAAGGAAGACC TGGTTTGGAAGGAGTATCCAATAGGATGCATTTAGCCTCAACTAACAGGCTGGCATCAAC AATATGCATGTGTATTGGCTCATATTACTGAAAAGTGCAGAAGTACAGTGGGTTTTGGAA TAGTTAATCAAGAAGTTCTGGAAGATGAATGGATAAAGAAATTGTGGTATATATATATAA TAAAATAATATTTAGCCATAAAAGAGAAGGAAATCCTGCAATTTGCAACAACAAGGGTGA ACCTCTAGGACATTATGCTAAGTGAAATAAACCAGACATGGAAAGGCAGATACCATCTGT TATGAATTATATGTGGAAAATAAAAAAAAATCAAACTTACAGAAGAGGGTAGAACCATGG CTGCCAGTGGGGTGGAGGAAACGGTGAAATTTGGGTCAAAGGGTACAAACTTTGAATTAT AAGAGGAACCCAGTTCTGGTGTACAGCATGAGTGGCGATGGATGTGTTAATTAATTAGAT TGTGATAATCATTACAGAATGTAAACATATACCAAATCATTATTTTGTACACCTTGAATA TATCCCATCTTTACTTGATAATTAAACATTTTAAAATTTAAAAAGACATGAGGGATTCCT GGGCAAGATGGCTGAATTAGAATAGTTCTGGTCTGCAGCTCCCAGAGAGACTAACGCAGA AGGCGGGTGATTTCTGCATTTCCAACTGAGGTACCCGGTTCATCTCAGTGGGACTGGTTA GACAGTGGGTGCAGCCCACGGAGAGTGAGCAGAAGCAGGGTGGGGAGTCGCCTCACCTGG GAAGTGCAAGGGGTTGGGGAACTCCCTCCCCTAGCCAAGGGAAGCTATGAGTGAGGGATG GTGCTATCTGGCCCAGATACTACATTTTTCCCACTGTCTTCACAACCCGCAGACCAGGAG ATTCCCTAGGGTGCCTACACCACCAGGGCCCTGGGTTTCAAGCACAAAACTGGGTGGCTG TTTGGGCAGACACCGAACTAGCTGCAGGAGTGTTTTTTCATACCCTAGTGGCACCTGGAA CTCCAGTGAGACAGAACTGTTCACTACCCTGGAAGGGGGGCTGAAGCCAGGATGCCAAGT GGTCTTGCTCAGCAGATCCCACCCCGATGGAGCCCAACAAGCTAAGATCTACTGGCTTGA AATTCTTGCTGGCAGCACAGCATTCTCAAGTCAATCTGGGATGCTCGAGCTTGGTAGGGG GAAGGGCATCCGCCATTACTGAGGCTTACGCAAAGCTTCTGTAGCCAGATTCCTCTCTAG ATTCCTCCTCTCTGGGCAGGGAATCTCTGAAAGGCAACAGCCCCAGTCAGGGGCTTATAG CTAAAACTCTCATCTCCCTGGGACAGAGCACCTGGGGAAAGGGGTGGCTGTGGGTACAGC ATCAGCAGGCTTAAATGTTCCTGCCTGCTGGCTCTGAAGAGAGCAGCGGATCTCCCAGCA CAGCGTTCAAGCTCTGCTAAGGGGCAGACTGCCTCCTCAAGTGGGTCTCTGACCCCCCCG TGCCTCCTGACTGGGAGACACCTCCCTACAGGGGTCGACAGAAAACTCATACAGGAGAGC TCTGGCTGGCATCTGGCGGGTGTCCCTCTGGGAAAAAGCTTCCAGAGGAAGGAGCAGGCA GTAATTTTTGCTGTTCTGCAGCCTCCGCTGGTGATATCGAGGCAAACAGGGTCTGCAGTG GACCTCCAGCAAACACCAGCAGGCCTGCAGAAGAGGGGCCTGACTATTAGAAGGAAAACT AACAAATAGAAAGCAGTAGCCTCAACGTCAACAAAAAGGACAACCACACAAAAACCCCAT CTGAAGGTCACCAGCATCAAAGACCAAAGGTAGATAAATCCCTGAAGATGAGGAAAAAGC AGCGCAAAAAGGCTGAAAATTCCAAAAACCAGAATGCCTCTTCTCCTCCAAAGGAGCACA ACTCCTCGCCAGCAAAGGAACAAAACTGAACAGAGAATGAGTTTGATGAATTGACAGAAG TAGGCTTCAGAAGGTAGGTAATAACAGACTCCTCCAAGCTAAAGGAGCATGTTCTAACCC AATGCAAAGGAAGCTGAGAACCTTGTTAAAGGTTACAGGAACTGCTAACTAAAATAATCA GTTTAGAGAACAACATAAATGACCTGATGCAGCTGAAGAACACAGCACAAGAACTTCGCG AAGCATATACAAGTATCAAGAACCAAATTGATCAGTTGGAAGAAAGGATATCGGAGATGG AAGATCAGCTTAATAAAGTGTGAAGATAAGATTAGAGAAAAAAGAATAAAAAGGAATGAA GAAAGCCTCCAAGATATATGGGACTATGTGAAAAGACCAAACCTACGTTTGATTGGTGTA CCTGAAATTGATGGGGAGAATGGAACCAAGTTGGAAAACACACTTCAGGCTGTTCTCCAG GAGAACTTTCCCAACCTAGCAAGATAGGCCAACATTCAAATTCAGGAAATACAGAGAACA CCACAAAGTTACTCCTAGAGAAGAGCAACCCCAAGACACATAATTGTCATATTCACCAAG GTTGAAATGAAGGAAAAAAATCTTAAGGGCAGCCAGAAAAAGGTTGGGTTACCCACAAAG AGAAGCCCATCAGGCTAACAGCAAATCTCTCTGCTGAAATCCTACAAACCAGAAAGAGTG GAGGCCAATATTCAACATTCTTAAAAGAATTTTCAACCCAGAATTTCGTATCCAGCCAAA CTAAGCTTCATAAGTGAGGGAGAAATAAAATCCTTTACAGACAAGCAACTGCTGAGGGAT ATTGTCACCACCAGGCCTGTCTTACAAGAGCTCCTGAAGGAAGCACTAAATATGGAAAGG AAAAAACGGGACCAGCTGCTGCAAAAACATACCAAATTATAAACACCATCGATGCTAGGA AGAAACTGCATCAACTAACAGGCAAAATAACGGGCAAAATAGCGTCATAATGACAGGGTC AAATTCACACATAACAATATTAACCTTAAATGTAAATGGGCTAAATGCCCCAATTAAAAG GCACAGACTGGCAAATTGGATAAAGACTCAAGACCCATCAGTGTGCTGTACTCAGGAGAC CTGTCTCACGTGCAAAGACACACATAGTCTCAAAATAAAGGGATGGAGGAAGTTTTATCA AGCAAATGGAAAGCAAAAAAAAGCAGGGGTTGCAATTCTAGTCTCTGATAAAACAGACTT TAAACCAACAAAGATCAAAAAAGACAAGGACATTACAAAATGACAAAGGGTGCAAAAAGA GGAGCTAACTGTCCTAAATATATATGCACCCAATACAGGAGCACCCAGATTCATAAAGCA AGTTCTTCAAGACCTACAAAGAACTTAGATCCCCACACAATAATAGTGGGGATTTTAACA CCCCACTGTCAGTATTAGACAGATCAACGAGATAGAAAATTAACAAGGATATTCAGGACT TGAACTCAGCTCTGGACCAAGGAGACCTAATAGACATCTACAGAACTCTCCACTGCAAAT CAACAGAATATGCATTCTTCTCAGCAGCACATCACACTTATTCTAAAACTGACCACATAA TTGGAAGTAAAACACTCCTCAGCAAATGTAAAAGAATGGAAATCATAACAATCAGTCTCT CAGACCACAGTGCAATCAAACTAGAACTTAGGATTAAGAAACTCACTCAAAACTGCACAA ATACATGGAAACTGAACAACCTGTTCCTGAATGACTACTGGGTAAATAACAAAATTAGGC AGAAATAAATAAGTTCTTTGAAACCAATGTGAACGAAGACACAATGTACCAGAATCTCTG GGACACAGCTAGAGCAGTGTTTAGAGTGAAATATATGGCACTAAATTCTCACAGGAGGAA GCAGGAAAGATCTAAAATTGACACCCTAACATCACAATTAAAAGAACTAGAGAAGCAAGA ATAAACAAATTCAAAATCTAGCAAAAGAGAAGAAATAGCTAAGATCAGAGCAGAACTGAA GGAGATAGAGACACTAAAAACCCTTAAAAAAATCAGTGAATCCAGGAGCTGGTTTTTTGA AAAGATCAACAAAATAGATAGACTGCTAGCCAGACTAATAAATAAGACAAGAGAGAAGAA TCAAATAGACAAAATTAAAAAAGATAAAGGGGATCTCACTACTGATTGCACAGAAATACA AACTACCATCAGAAAATACTATAAGCACCTGTATGCAAATAAACTAGGTTATCTAGAAGA AATGGATAAATTCCTGGACACATACACCCTCCAAAGACTAAACCAGGAAGAAATCGAATC CCTAAATAGACCAATAACGAGTTCTGAAATTGAGGCAGTAATTAATAGCTTACCAACCAA AAAAAGCCCAGGACCAGATGGATTCACAGCCGAATTGTACCAGAGGTACAAAGAGGAGCT GGTACCATTCCTTCTGAAACTATTCCAAACAATGGAAAAAGAGAGACTCCTCTCTAACTC ATTTTATGAGATCAGCATCATCCTGATGCCAAAACCTGGCAGAGAGACAATAAATAAAGA AAATTTCAGGCCGGTACCCCTGATGAACATCAATGCAAAAATCCTCAATAAAATACTGGC AAACCGGATCCAGCAGCACATTAAAAAGCTTATCCACCATGATCATGTTGGCTTTATCCC TGGGATGCGCAAGGCAGGTTCAACATATGCAAATCAATAAACATAATTCATCATATAAAC AGAACCAATGACAAAAACCACATGATTACCTCAATAGATGTAGAAAAGGCCTTCGATAAA ATTCAACACCCCTTCATGCTAAAAACACTCAATAAACTAGGTATAGATGGAACGTATCTC AAAATAATGAGCTATTTATGACAAACCCACAGCCAATATCATACTGAATGGGCATTTCAA AGTATTCCCTTTGAAAACCAGCACAAGACAAGGATGCCCTTCGTCACCATTCCTGTGTAT TGGAAGTTCTGGCCAGGGCAATCAGGCAAGAGAAAGAAATAACAGGCATTCAAATAGGAA GAGAGGAAGTCACGTTATTTCTGTTTGCAGATGACATGCCTGTATATGTTTGTATATTTG GAAAACCCCGTCATCTCAGCCCAAAAACTCCTTAAGCTGATAAGCAGCTTCAGCAAGGTC TCAGGATACAAAATGTGCAAAAATCACAAGCATTCCTATACGCCAATAACAGACAGCCAA ATCATAAGTGAACTCCCATTCACAGTTGCTACAAAAAGAATAAAATACCTAGGAATACAA CTTACAAGGAATGTGAAGGACCTCTTCAAGGATAACTACAAACCACTGCACAAGGAAATA AGAGAGGACACAAACAAACGGAAAAACATTCCATGCTCATGGATAGGAAGAATCAATATC ATGAAAATGGCCATACTGTCCAAAGTAATTTATAGATTCAATGATATTCCCATCAAGCTA CCATTGACTTTCTTCACAGAATTAGAAAAATCTACTTTAAATTTCATGTGGAACCAAAAA GAGCCTGTATAGCCAAGACAATTCTAAGCAAAAAGAACAAAGCTGGAGCGTCATGCTACC TGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATAGTACTCATACCAAAA CAGATATATAGACCAATGGAACAGAACAGAGGCCTCTGAAATAGGTCCACATGTCTACAA CCATCTGATCTTTGACAAACCTGACAAAAACAAGCAATGGTGAAAGGATTCCCTATTTAA TAAATGGTGTTGGGAAAACTGGCTAGCCATATGCAGAAAATTGAAACTGGACCCCTTCCT TACACCTTATGCAAAAATTAACTCAAGATGGATTAAGGTTTTAAATGTAAGACCTAAAGC CATAGAAAGCCTAGAAGAAAACCTAGGCAATACCATTCAGGACAGTGGTATGGGCAAAGA CTTCATGACTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAGTGGGATCT AATTAAAGAGCTTCTGCCTAGCAAAAGCAACTGTCGTCAGAGTGAACAGGCAACCTACAG AATGGGAGAAAATTTTTGCAATCTATCCATCTGACAAAGGCCTAATATACAGAATCTACA AGGAACTTAGACTAATAAGAAAATAACTCCATCAAAAAGTGGGTGAAGGATATGAACAGA CACTTTCAAAAGAAGACATTTATATGGCCAACAGACATATGAAAAAAGCTCATCATCACT GGTCATTAAAGAAATGCAAATAAAAACCACAATGAGATACCATCTCCAGTTAGAATGGTG ATCATTAAAATGTCAGGAAACAGCAGATGCTGGAGAGGATGTGGAGAAATAGGAATGGTT CTATACTGTTGGTGGGAGTGTAAATTAGTTCAGCCATTGTGGAAGACACTGTGGGGATTC CTCAAGGATCTAGAACTAGAAATACCATTTGACTCAGTGTGCCTGGAATTGGTTCCTTCC GGTGGGTTCTTGGTCTCACTGACTTCAAGAACGAAGCCGTGGACCCTCGCGGTGAGTGTT TCAGTTCTTAAAGATGGTGTATCCAGAGTTTGTTCCTTCAGATGTTCAGAGGTGTCCAGA GTTTCTTCCTTCCGGTGGTTTCGTGGTCTTGCTGACTTCAGGAGTGAAGCTGCAGACCTT CACAGTGAGTGTTACAGCTCTCTCTTTCTTTTTTTTTTAAATTATACTTTAAGTTCTAGG GTACATGTGCACAACGTGCAGGTTTGTCACATATGTATACATGTGGCATATTGGTGTGCT GCACCCGTTAACTCATCATTTACATTAGGTATTTCTCCTAATGCTATCCCTCCCTCCCTC CCCCCACCCCATGACAGGCCCTGGTGTGTGATGTTCCTCACCCTGTGTCCAAGTGTTCTC ATTGTTCAGTTCCCACCTGTGAGTGAGAACATGCAATGGTTGGTTTTCTGTCCTGGCGAT AGTTTGCTCAGAATGATGGTTTCCAGCTTCATCCATGTCCCTACAAAGGACATGAACTCA TTCTTTTCTATGGCTGCATAGTATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAG TCTATCATTGATGAACATTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCACA ATAGACATACATGTGCATTTATCTTGATAGCAGCATGATTTATATTCCTTTGGGTATATA CCTAGTAATAGGATGGCTGGGTCAGATGGTATTTCTAGTTCTAGATCCTTGAGGAATTGC CACACTGTCTTCCACAGTGGTTGAACTAGTTTACATTCCCACCAGCAGTGTAAAAGTGTT CCTGTTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCCATT CTAACTGGTGTGAGATGGTATCTCGTTGTGGTTTTGATTTGCATTTCTCTGATGGCCAGT GATGATGAGCATTTTTTCATGTGTCATGTGTCTGTTTCATGTGTCTGCATAAATGTCTTC TTTTGAGAAGTGTCTGTTCATATCCTTCGCCCACTTTTTGATGGGGTTGTTTGATTTTTT CTTGTAAATTTGTTGAAGTTCTTTGTAGATTCTGGATATTAGCCCTTTGTCAGATAGGTA GATTGTGAAAATTTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTT TGCTGTGTGCAGAAGATATTTAGTTTAATTAGATCCCATTTGTCAATTTTGGCTTTTGTT GCCATTGCTTTGGTGTTTTAGTCATGAAGTCCTTGCCCATGCCTATGTCCTGAATGGTAT TGCCTAGGTTTTCTTCTAGGGTTTTTATGGTTTTAGGTCTAACAATTAAGTCTTTAATCC ATCTTGAATTAATTTTTGTGTAAGGTGTAAGGAAGGGATCCAGTTTCAGCTTTCTACATA TGGCTAGCCAGTTTTCCCAGCACCATTTATTAAATAGGGAATCCTTTCCCCATTTCTTGT ATTTGTCAGCTTTGTCAAAGATCAGATGGTTGTAGATGTGTGGTATTATTTCTGAGGGTT CTGTTCTGTTCCATTGGTCTATATCTCTGTTTTGGTACCAGTACCATGCTGTTTTGGTTA CCATAGCCTTGTAATATAGTTTGAAGTCAGGTAGTGTGATGTGTCCAGTTTTGTTCTTTT TGCTTAGGATTGTCTTGGCAATGCGGGCTCTTTTTTGGATCCATATGAACTTTAAAGTAG TTTTGCAATTCTGTGAAGAAAGTCATTGGTAGCTTGATGGGGATGGCATTGAATCTATAA ATTATCTTGGGCAGTATGGCCATTTTCACGATATTGATTCTTCCTATCCATGAGCATGGA ATGTTCTTCCATTTGTTTGTGTCCTCTTTTATTTCGTTGAGCAGTGGTTTGTAATTCTCC TTGAAGAGGTCCTTCACAAACTTTTAAGTTGGATTCCTAGGTATTTTATTCTCTTTGAAG CAATTGTGAATAGGAGTTCACTCATGATTTGGCTGTCTGTCTGTTATTGGTGTATAGGAG TGCTTGTGATTTTGCACACAGATTTTGTATCCTGAGATTTGCTGAAGTTGCTTATCAGCT TAAGGAGCTTTTGGGATGAGACGATATGGTTTTCTAAATATACAATCATGTCATCTGCAA ACAGGGACAATTTGATTTCCTCTTTTCCTAATTGAATACCCTTTATTTCTTTCTCCTGCC TGATTGCCCTGGCCAGAACTTCCAACACTTTGTTGAATAGGAGTGGTGAGAGAGGGCATC CCTGTCTTGTGCCAGTTTTCAAAGGGAATACTTCCAGTTTTTGCCCATTCAGTATAAAAT TGGCTGTGGATTTGTCATAAATAGCTTTTATTATTTTGAGATACGTTCCACCAATACCTA GTTTATTGAGAGTTTTTAGCATGAAGCGCTGTTGAATTTCGTCGAAGGCCTTTTCTGCAT CTGTTGAGATAATCGTATGGTTTTTCTCTTTGGTTTTGTTTATATGATGGATTATGTTTA TTGGTTTGCGTATGTTGAACCAGCCTTGTATCCCAGGGATGAAGCCAACTTGATCATGGT GGATAATCTTTTTGATGTGCTGCTGGATTCAGTTTGCCAGTATTTTATTGAGGATTTTTG CATCGATGTCATCAGGGATATTGGTCTAAAATTCTCTTTTTTTTGTTGTGTCTCTGCCAG GCTTTGGTATCAGGATGATGCTGGCCTCATAAAATGAGTTAGGGAGGATTCCCTCTTTTT CTTTTGATTGGAATAGTTTTAGAAGGAATGGTACCAGCTCCTCTTTGTACCTCTGGTAGA AATCGGCTGTGAATCCATCTAGTCTTGGACTTTTTTTGGTTGGTAGGCTATTAATTATTG CCTCAATTTCAGAGCCTGTTATTAGTCTATTCAGAGATTCAACTTCTTCCTGGTTTAGTC TTGGGAGGGTGTATGTGTCAAGGAATTTATCCATTTCTTCTAGATTTTCTAATTTATTTG CATAGAGGTGTTTATAGTATTCTCTGATGGTAGTTTGTATTTCTGTGGGATCGGTGGTGA TATCCCCTTTATCATTTTTTATTGCATCTATTTGATTCTTCTCTCTTCTTTATTAGTCTT GCCTAGTGGTCTATCCGTTTTGTTGATGTTTTCAAAAAACCAGCTCCTGAATTCATTGAC TTTTTGAAGGGTTTTTTTGTGTCTCTTATCTCCTTCAGTTCTGCTCTGATCTTAGTTATT GCCTTCTGCTAGCTTTTGAATGTGTTTGTTCTTGCTTCTCTAGTTCTTTTAATTGTGATG TTAGGGTGTCCATTTCAGATCTTTCCTGCTTTCTCTTGTGGGCATTTAGTGCTATAAATT TCCCTCTACACACTGCTTTAAATGTGTCCCAGAGACTCTGGTATGTTGTGTCTTTGTTCT CATTGGTTTCAAAGAACATCTTTATTTCTGCCTTCATTTTGTTATGTACCCAGTTTTCAT TCAGGAGCAGGTTGTTCAGTTTCTATGTAGTTGAGGGGTTTTGAGTGAGTTTCTTAATCC TGAGTTCTAGTTTGATTGCACTGTGGTCTGAGAGACAGTTTGTTATAATTTCTGTTCTTT TACATTTGCTGAGGAGTGCTTTACTTCCAACTGTGTGGTCAGTTTTGGAATAAGTGTGAT GTGCTGAGAAGAATGTATATTCTGTTGATTGGGGGTGGAGAGCTCTGTAGATGTCTATTA GGTCCGCTTGGTGCAGAGTTGAGTTCAATTCCTGAATATCCTTGTTAACTTTTTGTCTCA TTGTTGTGTCTAATGTTGACAGTAGGGTGTTAAAATCTTCCGTTATTATTTTGTGGGAGT CTAAGTCTCTTTGTAGGTCTCTAAGGGCTTGCTTTATGAATCTGGGTGCTCCTGTATTGG GTGCATGTATATTTAGGAGAGTTAGCTCTTCTTGTGGAATTGATCCCTTTTCCATTATGT AATGGCCTTCTTTGTCTCTTTTGATCTCTGTTGACTTGAAGTCTGTTTTATCATAGACTA AGATTGCAACCCCTGCTTTTTTTGTTTTCCATTTGCTTGGTAGATCTCCCTCCATCCCTT TATTTTGAGCCTATGTGTGTCTCTGCACATGAGATGGGTCTCCTGAATACAGCACACTAA TGGCTCTTGACTGTATCCAATTTGCCAGTCTGTGTCTTTTAATTGGAGCATTTAGCACAT TTACATTTAAGGTTAGTATTGTTATGTGTGATTTTGATCCTGTTATTATGATGTTAGCTG GTACTTTTGTTCATTAGTTGATGCAGTTTCTTCCTAGCATCAATGGTCTTTACAATTTGG CACGTTTCTGCAGTGGCTGGTACCAGTTGTTCCTTTCCTTGGTTAGTGCTTCCTTCAGGA GCTCTTGTAAGGCAGGCCTGGTGGTGACAAAATCTCTCAGCATTTGTTTGTCTGTAAAGG ATTTTATTTCTCCTTCACTTATGAAGCTTAGTTTGGCTGGATATGAAATTCTGGGTTGAA AATTCTTTTCTTTAAGAATGTTGAATATTGGACCCCACTCTATTCTGGCTTGTAGAGTTT CTGCCGAGAGATCTGCTGTTAGTCTGATGGGATTCCCTTTGTGGGTAACCCGACCTTTCT CTCTGGCTGCCCTTAACATTTTTTCCTTCATTTCAACTTTGGTGAATCTGACAATTATGT GTCTTGGAGTTGCTCTTCTCGAGGAGTATCTTTGTGGCATTCTCTGTATTTCCTGAATTT GAATGTTGGCCTGCCTTGCTAGTTTGGGGAAATTTCCCTGGATAATATCCTGAAGAATGT TTTCCAATTTGGTTCCATTCTCCCCATCACTTTCAGGTACACCAGTCAAATGTAGATTTG GTCTTTTCACATAGTCCTGTATTTCTTGGAGGCTTTGTTCATCATGTCTTTTTACTCTTT TTTTCTAAACTTCTCTTCTTACTTCATTTCATTCATTTGATCTTCAATCACTTATACCCT TTCTTACCCTTGATCAAATCGGCTACTGAAGCTTGTGCATGCGTCATGTAGTTCTTGTGC CATGGTTTTCAGTTTCATAAGGTTATTTAAGGTCTTCTCTACACTGTTTATTCTAGTTAG CCATTCGTCTAATCTTTTTTCAAGGTTTTCAGCTTCTTTGCGATGGGTTCGAACATCCTT CTTTAGCTCAGAGAAGTTTGTTATTACCAATCGTCTGAAGCCTTCTTCTTTCAACTCGTC AAAGTCATTGTCCATCTAGCTTTGTTCCATTGCTGGCGAGGAGGCGCGTTCTTTTTGGAG AAGAGGCGCTCTGATTTTTAGAATTTTCAGCTTTTCTGCTCGGGTTTCTCCCCATCTTTG TGGTTTTATCTACCTCTGGTCTTTGATGATGGTGATGTACAGATGGGGTTTTGGTATGGA TGTCCTTTCTGTTTGTTAGTTTTCTTTCTTACAGTCAGGACCCTCAGCTGCAGGTCTGTT GGATTTTGCCGGAGATCCACTCCAGACCCTGTTTGCCTGGGTATCACCAGCGGAGCTGCA GAACAGCAAATATTGCTGAACAGCAAATGTTGCTGCCTGATCCTTCTTCTGGAAGTTTTG TCTCAGAGGGGCACCCGGCTGTATGACATGTGAGTCGGCCTCCACTGGGAGGTGTCTCCC AGTTAGGCTACTCAGGGATCAGGGACCCACTTGAGGCAGTCTGTCTGTTCTCAGATCTGA AACTCCATGCTGGGAGAACCACTACTGTCTTCAAAGCTGTCAGACAGGGACGTTTAAGTC TGCAGAAGTTTCTGCTGCCTTTTGTTCAGCTATGCCCTGCCCCCAGAGGTGGAGTCTACA GAGGGAGGCAGGCCTCCTTGAGCTGAGGTGGGCTCCACCCAGTTTGAGCTTCCTGGCCAC TTTGTTTATGTACTCAAGCCTCAGCAATGGTAGACACCCCTTCCCCAGCCTCGCTGCCAC CTTGCAGTTCGAGCTCAGACTGCTGTGCTGGCAGTGAGTGAGGCTCCGTGGGCATGGGAT CTTCCAAGCCTGGCACGGGATATAATCTCTTGGTGTGCCATTTGCTAAGACCATTGGAAA AGCGCAGTATTAGGGTGGGAGTGTCCTGATTTTCCAGGTACTATTCTGTCACGGCTTCCC TTTGCTAGGAAAGGGAATTCCCTGATCCTTTGTGCTTCCTGGGTGAGGCAATGCCCCACT CTGGTCCGTGGGCTGCACCCACTGTCCGACAAGCCCCAGTGAGATGAACCCAGTACCTCA GTTGGAAATGCAGAAATTACCCATCTTCTGTCGCTCACGCTGGGAGCTGTGGACTGGAGT TGTTCCTATTTGGCCATCTTGGAACCTCCCCCGAGTGTTACAGCTCTTAAAGGTGGCGCA TACGTAGTTGTTTGTTCCTCCCGGTGGGTTCGTGGTCTTGCCGACTTCACGAGTGAAGCT GCAGACCTTTACAATGAGTGTTACAGCTCTTAAAGTTAGCGTGGACCCAAAGAGTGAGCA GCAGCAAGATTTATTATGAAGAGTGAAGGAACAAAGCTTCCACAGTGTGGAAGGGGACCC AAGTGGGTTGCCGCTGCTGGCTCGGGTGGCCAGCTTTAATTCCCTTATTTGGTGCCGCCA CGTCCTGCTGATTGGTCCATTTCACTGACCACTCATTGGGCTGTTTTACAGAGTGCTGAT TGGTGCATTTACAAACCTTTAGCTAGACACAGAGCACTGATTGGTGCGTTTTTACAGAGT GCTGATTGGTGTGTTTACAAACCTTTAGCTAGACAAACAGCACTGATTGGTGCGTTTACA ATCTTCCAGCTAGACAGAAAATTTCTCCAAGTCCCCCCCTGACCCAGAAGCCCAGCCGGC TTCACCTCTCACCGGCAATCTCATTACTGGGTATATACCCAAAGGATTATAAATCATTTT GCTATAAAGACACATGCACACGTATGTTTATTGCAGCACTATTTACAATAGCAAAGACTT GTAACCACCCGAAATGCCCATCAATGATTGACTGGATAAAGAAAATATGGCATATATACA CCATGTAATACTATGCAGCCATAAAAAATAATGAGTTCATGTCCTTTGCAGGGACGTGGA TGAAGCTGGAAACCATCATTCCCAGGAAACTACACAGGAACATAAAACCAACCACCACAC ATTCTCACTCATAAGTGGGAGCTGAACAATGAGAACATATGGGCACAGGGAGGAGAACAT CACACACTGGGGCCTGTTGGGGAGTGGGGGGCTAGGGGAGGGATAGCATTAGGAGAAATA CCTAATGTAGATGTCGGGTTGATGGGTGCAGCAAACTACCATGGCACATGTATACCTGTG TAACAAACCTGCACATTCTGCACATGTATCCCAGAACTTAAAGTATAATAACAACAACAA CAACAAAAAACAAGAAAACATGTATTAAGAAAGAAAGAAAGGTTTTTGGTGCTAATGATC AAGAACCTTTCTGCGATATCATCTAGGATCTAGGATCCAGGATCCAGGTGTTTTCTGACT CTGTCTTTCACACTGATGGTTGGTACTCCTTATGGCTCATGGGTGGAGCCTGTGGCATCA GGGCTACCTGTGCCTTTGTTCACATGTGGTAAGAGAAAGAGAGAACTTAGTAATTCTCTT ACAAAGCCAGAAAGCTTCATTCTCAAAAGCTTCCATGAGACCTCTTCTCCCTTGTCTGTG GCCCAGATTGGATCACGTGCCTATTGGTAAACCAACCTATGGGAATGGGAGTGGCATCCC TTTTAGATAATCAGGTTGATTCCAGGATTCTGGGTAGACAGCTTAAATGTTCACTTGTGC ACAGAAGATTGAGTGCAGTTTAAACATGTCAAGGAGCTGGTGGCATAACAAGGTTGCAAC TTGCTTCAGAGGTTACATTTATGAGTCTGGATTCTGAAAGGAGCAATATGTGTTTTAAAG GAAAAAAGCAAGAGACAGTGTTCTTGAATTCTTCAGTGTTTTCAGACTCTTTCTGTGAAT GTGTTACTCTGAAAGTTTGTAGTAGTACAGACCTGGCCAGTTTTGTACAAGCAAAGCGGA GCAAACATTCAGTCCACTGATTCCCAAGGTGCTGAGGACAGAAGTTAGTGGAACAGTCCA CGGTGGTGTAAGCTGAGTACTGACACTTTCCTCATTTACCAGCTAATTCTCCCTTTTACC ATTTGATTTGACTTTGCCGAAATTGGTCAGATGGGTAAGGTTTGGGTGGCTGAAGCATAT GACACTTTTCAGTTTTAGAGCTCATTAGGTGTTTTTTACCAGTATTTCAACTTGATGCAT TACAAATTTGATATAATTCAGGGAAAGGACCTGTATGGGATAAGAAGTAATCAAAATTAT TCTGACCTTTTTATGTAGTGTTTCACCATAAACATATTGTTTACTTTTGTCTCTTCTTTA AGGAATATATACAGCATTAAAAGATGAGAGTTAAGTAAACTCTGGGCTATCATACAGTGG AATATGAATAAAATACATACATACACACACCCCCTTCCTTAATCCCTCCCCACACCCCTA AACTTTTCTGGCAGAGGCAGTCGTGCCCACCAAATATTCTAATTGCTTTCCGCATTTCCC AGCCACCTTTCAGTTGCGTGGGCATGTGTCTCATGATGGACAATGGGCTGTGAAAGAGAT ACATTTTTCTTACAGGCCATGGCAGTAAAAGATCCATGCAGAATTCTTCCTGTTTTTCTC CCATGAGGAGACTGAAGGGACCATGGATTCCAGATGGGCAGCTATAAAATGGAAGGATCT CTGTTAGTTTGAGTCGCTGAGTGACTGTGTGAAGCCTGTGTGGAGCTGAGCCTCTTGTTG ACCCTTGTAGGCCATTTAACATGGGGGAGAAATGAACTTTTGTTCTGTTCATCCACTGGC ATTTGGAATTGTTACAGGAGCACAATGAATACATACCTCCTTTCAATATTTACTCTTTGT CTGGAAGCACCTTTCTCAAACCTAATCCTTACCTCCTTGCCTGCTCACCCAGTAGAGCCT ACATAAAAGTTTCTCTCTTTTTGATATCTCAGTGTTGCCATTATAGATCTCAGTTATTGT GCTGATCTGTTATTACTCATCAGCATAGATGCCATCAGGACCTACTAAGCTAAGTAGGGT CATTTGCTTTAAGAGATGAACTGAGTTGAGTAGTAAAATGTATTCCCTAAAAAAGCATGT GTGAATCTACAGTAACTGGAGTAACTAGTCTTATGAAAAATTGGAGACTAGAAAATTGCA TTCAAGGTTTGGTAGCTTGATATTTTGTTAAATCAGTACTATTTCCGTTCCTCCCCCAAG TTTGTTTAGTTTCATTTTTTAAAAAGACTTTATTGAGGATAATCGACATAAGAAGGTGTA CATATTTAATGTATACAACTTGATGAGTTTGGAAATAAGTATATATCCAAGAGACCATCA CCACAAGCTATCCACCCTCTCTGAAAGTTTCCTCCTGTCCTCTTTATTATTGTTTTTTTC CTGAGAAAAACACTTCATATAATATCTACCCTCTTAGCAAATTAAGTATACAGTACAGTG TTGTTATCTCCAGGCAGTGTGCTTTACAGTAGATCTCTAGGAATTATTTGTGTTGTCCAA ATTATACACTGTTGTATTCAAGTTATATACAAGTTGTACCTTGATAGTTCAAGTTTAATA AATCTCTTTGTAGTTACCCATGAGATCTGATAGAAGATCTGGCTAATATTTCTGAAGAAA TTATTCCTTGGAGAATGAAGTAGCTTTTAGAAACATATTTTTATGTCCCAGAGGAACCCC AAGACCTGTTCTTCACTAACATTATAGGCCGTCATAAATAACCTACCCACACACCACGAA AATTGTCTTTGGTTTGGAGCAGAGGTCAAAAAGTGGGACCCATGCTTGCTTTGGCCCACA AAGTGGTTTTTGCATAAGGAAAATAGGTGCCAACATTTAGAAATCAGGAAATTTAACACA AAACTCTAGATTTCTGGCTGCTCTTTTAAAATGGGTGGATGTGGCCACTCTGAGCCTGTG TTAGCAGAAGGTTGGAATGGAAACAACAGAACTGAGGCATCCCATTTTCCACAGCCCTCG CTTGGCTCGGTTTGCCTCTCACTCACTGCACTCACCCCACTACTGCAGGCATTTTGGTTG GAGGGTTTTTTTCTCCATTATCATGCACATATTTCCTGGGAGAATCCTGCCAGTGATTTA GGACTTACTTTCATCTAATAAATATTCACTTAGTATTCACTTAGTTTCACTTACTCTGGT AAGCAGTCCACGTGACATATAATTGGAAAGCCTTACATAATTGTTGCCTCTTCTGTTCTC TTCATGTTATCTCCTTTATCACTATAGCATTAAATTTACTCTAATGATACTTATTGAGAT CCTATGTGCTAGATTCTAAGGGTTTAAAAATGAATGAGATACAGTTGTTGGCCACCAGGA GCCCAGCTTGTTGGTGATATTGTTAAAGAAATGAGCACTATAATGTTGCCACAATATACT GAGTATGAGAGAGAGAAAGAGAGAGAGAGAGAGACAGGTGACCTCTGATGGGGAGAGTTT TGGAGGAGTTTTCTTAGTGGAAGGCACATTTGAACTAGGTTTTCATTGATAAGTAGGAGT TCTCTAAACTTTTGAGATAAATTAGCTAAGCCTGCCTATAGTGTGGACCAGTTTGAAACT TTTACTAATTCTTAGTGAAGCATGAAAGGTAGTCTTCACTTTGCATGGCCTATGGGGACA TCAAAATGACTACGCAAGTTGAAACTGTGCAAAACACTTTCATCAATCAATGGGAACATT AATTGATCTACAGCCTTTAAAATTTTTTGTCAAAATATTTAGTCTGTTTTATTGTCAGTC ATAAATGTATAGGAAAATGAAAAAAGTAAAACTAATATTTATTCAGTACACTCTATTTAA ATGTTGGAAACACTGAAAATTAACACGTATTATTTCTTTGTAAAAACTTGTTAAGTTCGA ATAGTGCTTTCTTTTTGTTGTATAATTTACAATAAGGCGAGAGCATCTTTTGTAAGCCTT AGGGAATTGTCATACTCAGGAGTCTGGATCAGCTTCCAGTGTTTCATCCTGTGTGCTTTC AAAGTTGTGAAAAATCTTCTAGAATTTCTTTAATGTGAAGTTTTTTGTGGCATCACTTCC TCAGGGATATCTCCATCTTTTTTTTTTTTGATTTTTTTTTTAAATTTTATTATTATTATA CTTTAAGTTTTAGGGTACATGTGCACAACGTGCAGGTTTGTTACATATGTATACATGTGG CATATTGGTGTGCTGCACCCATTAGCTCGTCATTTAGCATTAGGTGTATCTCCTAATGCT ATCCCTCCCCACTCTGCCCACCCCACAACATTCCCGAAGTGTGATGTTCCCCTTCCTCTA TCTATGTGTTCTCATTGTTCAATTCCCACCTATGAGTGAGAACATGCGGTGTTTGGTTTT TTGTCCTTGCGATAGTTTGCTGAGAATGATGGTTTCCAGTTTCATCCATGTCCCTACAAA GGACGTGAACTCATCATTTTTTATGGCTGCATAGTATTCCATGGTGTATATGTGCCACAT TTTCTTAATCCAGTCTATCGTTGTTGGACATTTAGTTTGGTTCCAAGTCTTTGCTATTGT GAATAGTGCCGCTATAAACATACATGTGCATGTGTCTTTATAGCAGCATGATTTATAATC CTTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAATGGTATTTCTAGTTCTAGATC CTTGAGGAATCGCCACACTGACTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAACA GAGTAAAAGTGTTCCTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTCTT AATGATCGCCATTCTAACTGATGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTC TCTGATGGCCAGTGATGATGAGCATTTTTTCATGTGTCTTTTGGCTGCATAAATGTCTTC TTTTGAGAAGTGTCTGTTCATATCCTTTGCCCGCTTTTTGATGGGGTTGTTTGTTTTTTT CTTGTAAATTTGTTTGAGTTCACTGTAGATTCTAGATATCAGCCATTTGTCAGATGAGTA GGTTGCAAAAATTTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTT TGCTGTGCAGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCAATTTTGGCTTTTGTTGC CATTGCTTTTGGTGTTTTAGACATGAAGTCCTTGACCATGCCTATGTCCTGAATGGTACT GGCTAGGTTTTCTTCTAGGGTTTTTATGGTTTTAGGTCATATCTCCATCTTTTTTGTCAC AGCCCCTTCCTTGCTCATATCAATAAATGTATCTTCACTAAGTTCCTATGGCTGAGCATC TGGAGTCACTCAAATAATCAGCAATGTCAGCATTCCCACAATCATCTCCTTCTCCTGTTC TCATTGACTTCTGATTCAGATTTCATTTCCAGCATTGTCATTTTTTGTTTCCTTGCTGCA CTTTCACCTTTGTTGGTCAGTTTCCCCTTTTGATTTACCCATTTTTGTAAAATGCCACGT GGTTTTATGACTGGGAGACAAGGAGTCATCATGACTACTTGCGTTGCCATCTGTGCAGAA CTGATAACAGCCATGTCGTGAGCAGTCACCAACAAACTTCAGAAGAGAAATGTGATTGGT CACTGATCCAGATGAGACCTGTTATTTATGGACTGAAGAGCTGGCAGTGAAATTTGTATT TGATGCAACAACTCACAGTTTGTGTATCATGGTAATGGAAATGTAAACTTGTGTTGTTGA GGGATTGGTGGGTTTTCAACCAAGCTGTGGTAACTGAAATTCATGCGTAGTGGAACTTTG TAAAGCGTGGACTATCTGTATTGACATTTTGAGTGGATTTGTCCTGTCCTCTGTTCAGAG TTTAGCAAGTATAACCCTGGCCACTTGACGGCATTCCATTAAAACCTCCTAATCGCTGTT AACAACCACAATGCTTCCCATATTTCCCATATGTGTTTGGGGGTGGTGGTGGGGACACTA ATCTAGTTTGGGAACCATTTGGGGGCTATCTCTGGGTCATTTCATCATTAATAAGGCAGG GAGTGTTTGGAAATAGCCACTCTGCTGCTGCTCAGTTACTTCAGCATTTATGGCTGAATT CTGAGAGGTGGAGCTTTCAGAGTGACCTCCCCTTAAGTATGTGGTGCCTTCTGCTTCCTT CATAGGCCAAGGGAGGCAGAAAGAGCCTCCTCCACAAGGAGTCACATGACCTGGATTCTA GCTGGACTTTGCCACATATCTGTCTGCCATATAACCTTTTTGAATCCTAATTTTCACAGC TATACAGTAAGTTTATCTGATTTACAAATTATTGTGAGGAATAAATGGAAAATGTATGTA AATACTGGGTGCACATGAGGAATTGTTCTGATGATGATGAATAACTGAATCATTGGTAGG CCTTTCTTGGACTACAATGAAATATAGCAGAACCCTCTAATGTCTCAGCAAAATAAACAT CCTCAGCTTTTAGACGCCGCCTCGAGTGAGAAGTTCACAACTTTCCCATCTCCGCTTAGT TGGCTCTTTTCTCACTTAGCTCCCTTCATGGTGAAATGCAGCGAATAGACTACCAGTCCA TTATTAGTCCATGAAATAACTTTAAACAGCCTCCTCCATGAGGGACAGACCTTATTTCTC TATTAATATAAGGAAAATAGAGCACAAATTAGTTGGTCTTTTAGAGAAACAGGCTGCAGA TGGCTCCCAGCTGGTAGCCATTTTGAATGATGAATTTTGAAGAGAGTATAAATGTTGAGT TAGAGAGTTCAGTGTTCTTTTCCTGGTCCAAGAATAAATATTTTTAGTAAAGTTAGTATA AATAGACCTGTCTTGGGGTGATCTGAGATGCTGATTACTTACCTGTGGATTTTTAACTTA ACGTCGGGAGCGAAGAATTTGGTGAAATAAGCATGTTAGTAGAATATTGCTGGCTTGGCA AAGGTTTCCTTCATCTGTAAGATATTATCCGGTAATTGCTGCAAACCTGCGACATATATG GTTTAGTGAACATTGGTAGATATGTTCTCTTTCCACATGGTATACTAATCTGGAATTTGT TGGAGATGAGATAAATCTATTATGACTTGAGGATTGAAGAATATGAATGGAAATTATTTT TATCATGGATGAAACTACTTGTAGAATTTGATTAGATTTTACTTGTTTATTTTATTCTAA CTTTAACAGTTTATTTCAAGAAAGTGAAATTACTTAAATGATTCAGTGTAAATCTCTGAA ATTTTTTCAATAGCTTACAGACTTTCTTCTAATTACAAAAAATTTGTAATTCTAGCTTTT GTAAACATTACCTTCCCTTCCTATCTCTACCTGCCAAAGCCCCACAGAAACTGAAAAGAA AACAGGTACATGCAATTTTATATTTATTTGGTACCTTTTTAATGTGGAAAAGAAGTACTT AAGTCTTGGATCAGGGAACATTACTTCCTATTTATAAAATTTAAATATAAAGTGGAAAGT TAAGATAACTATTTAACTTCCAAAGCTGTTACATATCTATAGCATGCTATCTTCATCAGA TTTTTCATGATGAAAAAAAAACTTTTGCAGATGAAATATAAAAAAAAATTTTCTTACATC AACAATCTTAATTTTAATTGTTTCATATATTTTAAAATTGATATTCTTTGGGCAAGCCCT TTTTTTACTATGAATATTTGCTATTCATCAAATCTGATATTACCGTAAGAATGAAGTTAC ACTTCAATTATTAGTTCCCTATAGGAAATGAGCACAGTAAATCTAACAACAGAAATTTAA AACAATTATATATTCAAATAATTACATTTTTAGATGGACTCCTCCAAAACCTCTTCTTTT CTTATGACATATAAGATTGCTAGTATAAGAGAGCAGCTAAGGAACCCTAACAGAGATTGG TAAAATTGAGAAGAGATTTCTTTTGTCAATGAGGATGTCCGGAAGTTGAAACTGACTTAC CTGAAATAGCAAAATCATACAGCATCCAGAATTATGAGTTAGAACAAGAGTTTTAAAATA CTTAATGTGTGTTTTAATGTTCATAGACAATGATTCAACATCAGATGTTTGTTCTTTGAG CTTTCTTTTGGTTTTGTGGTGGTGAAAACAGGGACAATAGTAAGATTTTAAGAAACTGGC TGGAATTCACTCTAGGGCTTCCCCCACCCCCCTGCTGAGACGACATCATTTTCTTCGTGG AGATTTTGTGGCTTTGCATAACTTGGCATTCTCTAATTTAACTGACAGCATGATATTTAT AGTTTTGTTACCATAAGGAAGTACTAATTATTTTAAACGTGTTTCCCAACTTTCAGGTAA CATTTCACACAACTGGGAGGCATCAGCGTCATATTTTGGGTGGGGAATGACCAGAATGAT CCGCTTAATTGAATTATTCCTTGAAAGCAAACTAAACATTTTGGACAACATATTGACTCA CTTAAACATATCACATGTTTCTTGGAAGTGATTTTCTTGTCAGATTTTTTGGGAATTAAT TGGATTGTGAGAAATGTACAATATCCTCTTGAAAAAGTGTCAGTGTCTCTGTCCATAGTA GCATTCATAAAATTATCTCTTTATTTCCATGATGTTTTTGAAAATGTTACTTTAATGTTT ATAGAAAATAATTCAAAATCAGTAGTTTATTCTTTCAGTTTTGGTTTTGTGAAGGTGCAA ATAGGGACAATAATGAAATTTTTTTAGAGATCAAAAACCAACTAGTTGAAACTCACTGTG GAGTTTTTTATTTCCCCTGAAACAAATAGTCATTTTCTTCTCAGCGGTTTTGTAGCTTCT TTGATTTCAGCCACATCTTCCTAGCCTTACCTTTTCCAGTTCCCTAATTTACCTGCCTTG ATGAACATTTAGGACATATTTTTGCATAGCTTGTGGATACAGAACCTCTGACTTGCTTAC TGCCCTATCTCCTGCCTTTGTGCCCTTTCTTCCACCCCATGCCACTTGCAGGAGATGTGC TTGTCGGCCCCCAGATCCAGTAACCTAGCTCCAGTACTGGGGTTCCTGGACCAACCTCCA CCCACACCCCCTGCAGGAGATGTGCTTGTCAGCCCCCGGATGCAATAATCTAGCTCCAGT ACTGAAGTTCCTAGACCAAACTCCACCCACACCCCCTGTAGAGACCTTGTGCTTCCTCCC CCACCTCCCACCCCCATGACAGAATGCGTCACACTCCACTACTCCCATCACTGGCTGAGG CTGTCACAAATTAATAGTGTGCCATATCAAAGCTGTAAGAATAGACCTGGAGTCATTGTA GATGATGGTTTTAAAAGCTTCATTGATCACATCCTAAGGAAAATTTTGACTTCCCGAAAG TGAGTAAGTGTGGCCCCTTCCTATGTGTAATCACTGCACTGGCCAGAATTTATTTGTAGG GAGTGTCAGTTAAGCACAGGTACTTGGTGGCTTCTCTTTCTGTCATGAATTCAAGTCAGT TTGAAGGGTATTAGTGTGCACAGCCGTAGGACAGTGGGGATGACAAGAGACACGTTACCT GTCCTGGATGTGTGGGGTGAGCCTTGAAGCCCTTCGGCTGCACTGAATCACCCTCAGGGC CTTGCAGGTACCAGCCCTCTCTTCTTTTTCCAGACCTTTCCACATGCCCTCCTCCTCTGC CTGGGACACATTCTTCACCTTTTCTCCAGTGAGCCAACTTTTTCTCCTCCTTTAGGTCAC GGCATTAGTAAGCATTTTCTTGAGGTAGCTTTCCTTGACTACCCACGACCGGGTTAGGAT CCCCTCTGTACATGCTCATATTGCACTGCCCCATTCTGAAACATGGCACACAGTACCATG ATGGCGGTTGGCTTATCTTCTCCCTTGTTAGATTCTGAGCTCCTGCAAGGTAGGAATTAT CTTGTTTGCTGTTGTATCCCTAGTATCTAGGACAGTGCCTGTCTGACCAAAAGTTATTAA TATCATCATAAATACAAGGGCTAATATCAAGCACTCAGTACGTGCCATGCTATGTGCTTT GGGTTTTCTTAAGTTCTCACAACAACTTTAGAAATAGATACGATAAAGGATTTTACAGAG GAGGAAATTGAGATTGATAGAAGTTAAGTAATTCGCTCAACACAGCACCCCTAGAAAGCA GCAGAGCTGGTATTTGTCTCCGGAGTCCCTGCTCATAATGGCTAGATTACACACAATGAT GAACAAATAAAGGATGTCTGCAAAGGCATCTGGCCAGAGCTCTGTGTGGGGCCAGCAGCT TCATGAATGATCCAAAGAGTTGGCATTAGCTGGCCACAAATGGTGTTCCAGAGAGTCACT TTTTTTCTAGTCATATAGGAGAGGTCAGCTCCAGATGTCAAATTCTAATTACTGGCAATT TGTTTTCTCTAAGAGGTTTGGCATTTACTGTGGCTCATAGAACTTTAGAGGTCGTGTGGT ACAGTATACAGAGCTCTAGTTTTAGAATTAAGGATTGGAGGCTTGGGCTTACCCCACTTT CCCTTAAACACAGTGTTGATGTGAGTAGGTTGAGAGTGGTCTTTGTGAACCCACTTCTCT GCACGGTATAGACAGGGAGTTGTAGTGTGGCTTAGAGGGAGTGTGTATAAAGCTGTCTTC CCAACTTGATGGCAGTTACCTGCTGCTCTTAGGATATTTTCTCTGGCATATTATTTTCTG TCATGGGCATCTATTGGTGCTTAATAAAATAAGTGTACATGCAGGGTTATTTCTGGGCAC TTCTACTAATGATTTAAGATTTCAGAAAGTTAGGTCTTCTACACATATGTCAAAAGGCAA ACTTATCTATTACAGTATCATAATATGGCCCTTGACTTCATTTACTGGATTAAGCAACTG CATTATTTAATTCAGAAAAAGAAAAGCATGTAGATTGTTTTCTTACTGCCTCCCCACCAA TAGCAACATTATAGTAAGATCTTATTTTTCTATCTTTCTTTCTTTTTTTTTTTTAAACAG TGTCTCAATCTGTAGCCCAGGCTGGAATGTGGTAGCATGATCATTGCTCACTACATCCTT GAACTCCTGGGCTCAAGTGGTCCTCCTGCTCCAGCCTCCTGAGATGGGACTACAGGCATG TGCCACCACATTCAGCTAATTTTTGTATTTTTTGTAGAGACGGAGTCTCACTATATTGTC CAGGCTGGTCACAAACTCCTGGCCTCAAGCAATCCTCCTGCCTCAGTCTCCCAAAGTGCT GGGATTATAGGCATGAGCTACTGCATGCAGCCTTATTTTTCTATCTTATCTCTTTGAGAG TCTTAAGTAACTTAGGGGAAAATTCTGAAACTAGTTAAATCCGGGGCCTGCTGTATACAG GGCAGAGAACTTAGTTTCTGTTTTGCAGAAACAGGTTGTAAATAAGTAAGTTCAGAAAAT AAGAGGATTTCCACTTGCAATAAGGGTTAGGAGGGAAATAAACACAGTGAGGTGGGAAAA ATAATTGTGGTTGGGTTGGTGTGAGAGTAGAAAAGGATGGGGAGTTGGACAAGATGGCAG CTGAAGTCTGAGCATGAGAAGGGGCTGGGACAGGAAATTCTGAGGAAGAGATAATAGTGA ATGCAGGGACTCAGAAGGGGAGCCTGCTGGGCATGTTTTTGGGGTGGCATCATGGCTGAT GCAGAGGGAGTTGAGAAAGATAACATTTTTTCTTTTTTACTAGTGGTTTAGACTTAACTA ACCAAGTTAATGGTGCAAACAGTAAACACATTAGCAGAGACAGGCATGAATGAGAGAAGC AGCAGCCGGGGCCAGGTGCTGTAGGATTAAGGTAACGAGCTCACCTGCCTTCAGGGCCAG ACCAGTACCTTGACTTAGTGAAGACAGTGTGGGCTTAACTTTTGTTCAATTTTTAATAGA GACATAAGTGTAGAGAAATATTGCTCTGAGAAAAACAGCAAACACCATGATAAATGGCAA GTGAGCAGTACAATGCCATGATGATGATGGCAAGTGGCCTTTGACCTCGCAGTCAGAGAA GTAGTAGGGACTGGGAGCAGCTCAGAGCCTGCTGGCCCTGACTCAAGGGGGCAGCTGTTT CTCAGTGCCAGCCAAGCATTGCCATGTGGGAATGTGAGTGGTCTGTGCTAAATTTGCCAA GTTTTCCAGAGAACCAGAAATCTGAATTGTTCTATGAAGTTCCCAGATTTAAAAATGTTG GCTCAAACTTTAAAAAACCTTACAATGAATAGACAAAATGCATCTGTGGGCTTACAGTCT GAAACATCTGCTGTAAGCCCTTTTATATTATGATAAAGGGGGCTCATGAAGTTTGATGTA TGTGAACCATTTCCTTGTGCCCGGTACGTAGCCAGTACTGAGGAGAAAAAGGTACTTATT ATTGATTGCACCCTTGATGTGTTTAGGTTGTTTTCACCATTAATATATTTAATGAACTCT CAATCCATATTAAAGATAAATATTATCCCAGTCTAATTCAAGTGATTAAATTAATACATG ATTTTTTTTTGCTGTTTGCATATTGGTTAGTAGTTTGCTCTATTAGTTTGGTTAATTCTA TGTTTGTCTTACATGAGCAAACATTAATCTAGTGTAATTCACGTAAAATTAGTGAGGAAC AGAGGACGCACATTTTAAATCCTGTTCTTTTCTTATTTACCGTCCATTTCCGTTGCTGGG CAGTCGTTGCTTCCCTCACTTGTCCTGGTGCTTCCACTCATTCAGGTCTTGAGACCTCCT AGACAGTGTTAGCTGCATGTGCAAGTGGGAAGGACCTTTGGCAAAAATGCCATTCTGAAC CAGGCAAAGGATGATGGGGAATGCAGTCTTACGACGTGATGTCGCGTTTAGAGGGTTTTC ATCAGTTTTAATGAAATACAAATGCACCCAAAGCAAGTTATTTTTTCCCCCAGGGAAAAA AATCTTCATTTAGTATGGTCTAACTCATGCAGTTTTGTATTACAGGAATCATGTTTGGTG TGTTGCAATCCCTTGGCAATTGTCTTGGGGAATTTTATTCAGCACAAGCATCTCTGATGG TTCTGGCATCAAGTTGGGTTAATTACTTGTTCATGTACTTTTTGGTTTGTGTCTATGTTA AAATTCTGAAGCATTGTGGAGAGGAACACTGGGAGTAACAAAATATATTTGAATATTTCT AATAGATTAAAGGCTTATAAAAACATCTCTTTTCCCCCCAGGGTTTTTTTTTTCTTTGCA TTGTTTTCAAATGAGATCATTTTGTATGAACATGAACTTAGGAACTTGAAAATAAACTTT TTTGTGTGTGAAAAATCTTATCTGTAAATACAAGTTTTTAATTGAGTCAATATTTCTCTC AATTTTTGTTACAGATCATGGAGGAAACAAATACGCAGATTGCTTGGCCATCAAAACTGA AGATCGGAGCCAAATCCAAGAAAGGTAAATTGTGAGAGGGCAAGAAATAGGTGGTTTTGA TAACTGAGATTATGGAATTACTGCAGGTTTGCTGGGGAGAAAACTAACCTTTATTCTTAA CACTTTTGTCCCAAAATGTTTGTTAAGTAGCAGTCTTTCAGGAGGATTTTCATAATTAAA AATTATAGTTTTTATCCAACAACAGAAAAATATTAACTATTAACATTATGATAGAAATGT AATTATGAAAGATATAGCAACCTGTGATTTCAAGGATGCTTATTCGATTGATATCCATGA GTCATGGTAACTCTTCACATGTTTTTAACACATAAATTTCTATTGTTTATATTTCAGGGT TCTTTTTTATGTACTACACAGATTTAATAGCTGGTTTTTTTTTTCCCTCCAGTATGATAT GAACCTTAGATTTCAGGTCTCGAGTGCTGCTTGTCTTCATCTATCAGACAGCAAAGAACC CACTAGATTTCTCTTTTAGGCTGAGTGTTTCCCTTGCCTGGTTTTACCCTATGGGACACT ACCCAGTGCATAGATGTTCAGAAATGAAACTAAAGGCCTCCCTAGTTTTCTCCCTGGATT ACATAGTGTTTTCAAATGTGACCTGCCAATATATATTTTTATGGATAGTTTTTAAAGTAT GACCTTAGTCTCAACAAACTTTGTGGAGTATATTTCATTAGAAGAATGCAGATGCATGTA GTTGTCAGGATGTAATGACAAATACCATCAAACAATTAAAAAATAATTGCAGTCTGAGCT GCAATTATCCATCATGGTCTGGCATTGTTATTGCTGCTGTTTAGTTTCGTATTTGCTGCC CCTTCTCCCCATGACTTACTACTAAATGATAACACTGTAAGATTTCTCAGTTTCCTTTCT TACTTCAGTCCAGTTTGCCTTCTTTTAATTGCATTTCGTTAGAGTTACTCATCACATGGA ATAAAAATTATTTTAGTTATTTAGTGAGTGTTGTTAGCTGGACTTGAATTGACTGGAATT CCTGTAGAAACTCCTATCTTGCTACTTTTTTTTTTTTTTTTTGGAGACAGGGTCTCACTC TGTCACCCAGGCTGGAGTGCAGTGGCACGATCATGGCTCACTGCAGCCTTACCCTCCCAG GCTCAAGCCATCCTCCCACCACAGACTCAAGTAGCTGGGACTATAGGACACCACCATGCT TGGGTAATGTTTGCATTTTTTGTAGAGATGGAGTTTCACTATATGTTGCTCAGGCTGGTC TTGAACTCCTGAGTTCAAGCAATTCTCCTGCCTTGATCTTCCAGAGTGTTGGGATTACAG GTGTGAGCCACCGCACCCAGCCTTGTTACCTTCTTAATTGTTATCATGGGCGGCAAGGAA TTGGGAACTTATATGCTAAATAATCATAAGAAGACATGGTGAATTTGCAAGTGCAATTCT GTATCTTTGTATAAGCCTGTATTTCTCAAGTGGTGTAGAATATATTCTTAATTAATCTTC AGTAATTTTTGTGGTATGTTGGAATGTTTTGTACTCATTATGCAGAAGAAGAAACTGCCG TTCATGGATTATCTAGCTGTTTGCAGCATTTAAAAATTTCTGTCCTACTACTTGAATAAA TTGGAACTTGAACATAGACTAAATCTTCTTTCCCTGTTGTCAGGCATTTTTACTTAAAGA ATAAAATTAGCTTTATTACTAGCCTAATAAAAATGCAACTTAATCAGTCTCCAAAGAAAA TCCCCAAGGAAACATGAACATTTAAACAATGCTAGATAACTTTTTATGTCTTATTCTCTT GCAGTATCCATGCTGTTGTTTTCCTCTCCCCATGCCATTATCCTGAGAAACTGAGAACTG ATTAGTTTTTGTTCAAAATGTGGTGGCAACATTAGACATTTCAGAAAATGTGGAGCTGAA TAGATTTTATTCATTGGTTTCTTGTCATTGACACTTAACCCATTCAAAATGGCCAACTAT ATTGCACATTTTGATTATATATTTTGCTTTGGAATTAAGAATATTTCAGCAGTACATTCG AGGGTGTTTGGCATAATTTCCACCTGGTTAAAATTAACCTTTGGAACTATGCCTAAGAAT TGATCCCTTCAGGCCTGGATCTATAGACATCATTTATTTTGTATTATTTATGAAGTGTTA TGGATGTATATAGTACTATATGATGCGCAGAATGCACTTAAAGAGAACATGGAAGGGAGA GAATCAGAAGTTTGCCTCAGAGGAATTTACTGTTGAGAATTTACTTGAGTTGCTCTTATC ATTTAAGCACACAGCTGCTGAATCAGTTCTTGGCTAACATCCCTGGTATGTGTATACCTA TATTATTTTTTAAATGATTCACTTCAGAGATGCAATTTTTGGACCATAATTTGTATTTAA TAAAAGTGAAATGAAAATGGCAGGAAGAATGTTAGAAGGTAATTATTTGCTCTTTGATCT GATGTGGCTTTTCCTTCTCACCCCTGAGTGTTGCAGAGGAAGGAATTGTTGGTCTTTAGA GCTTTTTCATTCCAGACTATTATTATTCAAGAGACCCAAGAATATAAATGTATTTAGGGA CTCATGCCGTGTTTTGGATGATTATTACATTCTAAATCCCATGGTGATGTGAAACTTTGG AATATACACATAATCCCCAGGCTGAGCTAGAGAGACAGTACAGCCATAGGTTTGTGTTGC ATTTCACTTTGGAGTTTCTAAAATGCATGTTGGCTAAATATTTGAGCCTAGACAAACATT TTTCGTGGTCGCTGTTACCACAGTTTGCCCCCTTCTTTACCTTACTGGAATTTAGTCCTG TGTTTCCTAAATTAGCTTCCATAGCTCTGTCTAAACTTTACTTTTTAAGCCATTAATCCT TTATCGAGAGCAGCTGTGTGAGTGGCCGTATGGCTCACTTGCTTGAAGAGCTGGAAGGAA GCTGCCTGGCAAGAAGGCAAGCAGCCAACAGCCTGAATTTGCCATCAGTTAGAGAGTTCA GATTCTTCTCCTCTAAAGATGTTGGCTTAGTAGTTCTGAGGCTGGTACTGGGAGCTGCTA TATTTAACAAGTTTCACTACTTGTTCTTATGGTCAGACTGAGTTTGGGAAACACAAATCT CACCATCTGATATGGAAATATCACTAAGAAGACCATGTGTTCTGAAGGCAAAGGGTGACC ACTACTGAGAAACAGCAGAGTCCTTCTACAGTCGCTTCTGGATAATGCCCATCTTGGCAT CTATAGAACTGCATTTTTATGGATGCATTAATTTCATTTTTCTATCATCTTTGTAGTCAG TTAATGTGGATTAGTTTAGAGTGATGACAACCTCATTGTTCTGTGCCTGTGCTAAATGTT GGATAAAAGACCATCTAATTTTTGTCCATTCCCTTTCCTCCTCCCTTTCTTATCATCTCA CTTTTCTTTCTTACCTTTCACTCCACTTTCATTCTTCTGTGACCGTATTCTAGATGGAAT ATAGTAGGGGCAAAAGTAATAGAAATATTTTCATGTGCACAGGGCATTTTAGGGAAGTGC ATGTTTTGTGATATAAACTAAGGAACTATAGAATTATTTAAACTTTTTTTAATTTTAGAT TCAGGGGTACATGTGCATATTTTTTACATGGGTTTATTGCATACTGGTGGAGATTGGGCT TTTAGTGTTACTGTTACACAGATAGTGAACATGGTACCCAATTGGTAATTTTTCAAGGCC TTGCCCTAGAATTTTTTAAAACATCTCTAGAGTATTTGAAATTATTGGAAGGTTGAGTCA TCATTAGAGCTGGAGAGAACTGAGAATTTAAGGTTCAGTATAATGGACATTTAAATGGGT GACTGTAGAATTGTCTTAAAGAGGGTCACGATTAAGAACAACAAAGCAATATTTGATATT TCTTCTGTATCACGTAAATTTATTTTGAGTGGATAAAAATTTAACTCCTTCTGACTCTTA GATTGAGAATACTAGAACAGTCTCCTTTACATTGAAAAATTTGAGGTTTGTGCCTGTGAA ACCAGTATTTAGGGATTAAGGTGTTTAATACCATACACCCTTACCAACAGAATAACTTCA AGGACTCATTAAAATTTTGAACATGCTATTCTGAATCATAGCCTTAATATTTTAAAATAA ATGCAGCTTCATTAAAGTACAAATTGCATTCTTAACAAATTTGATTGTTTTGCCAAATAG AAGTCCTGCCAGACCTGCTTTAAGAAATACATAAAAATGATTTGCAATGAGCATTTATCA CACTGGTATATTGTGCTGTGAGCTTCATGATGCTAGATAAGTTTGTTTTCTTAAACAAGG TAAACATTTTTCTCACAGTCTTCTTTTGCTCTTAATCTGCTCATCAGTCTCTTCTTAGAC TGGCGAAGGTGAACGGTAAATGATATGGTTTGGCTGTGTCCCCACCCAAATCTCATCTTG AATTGTAATCCCCTTTATCCCCAGATGTCAAAGGAGAGATCTGGTGGGAGGTGATTGGAT CATGGGGGTGGTTTCCTTCCACGCTGTTCTCATGATAGTGAATGAGTTCTCACAAGATCT GATGAGTTTAAAACTGTTTGAAAGTTCTTCCTTCCCACGCCCTCTCTCCCCTGCTGCCAT GTAAGATGTGCCTGCTTTCCCTTCTGCCATGATTGTAAGTTTCCTGAGGCCTCCCCAGGC ATGCAGAACTGTGGGTCAATTAAAGCTCTTTCCTTTATAAATTACCCAATCTCAGGTATT TCTTTATTGCACTATGAAAACAGACTAATACAGTGAGTAAAAAAATGTTTAAAGTTTTTA AGCCAAATTTCAAATAACTGAGGTCAGCATGAGTGAAGCTTTATTGCAGAGTTAAACCAA GTGATAGGAACTAATCCCTGCAAGTGGTCCTTGCATGATGACTTAGGAAACCCCAGGACT AGCAGGAATGAGAGGCATTGACTGGGTTACTTGATGTTTCCTGGTTTGGAGACAATTTGG CACCAAGTTTAGCCATTCTCTTCCTCCCAGAATCAACAAAAGAATCTTCGTAATTCCATG AGGTTTTATTGTTTTTGGTTACATTTTATCAGAACAAGTAGGTATCTAATAGAAAATGTT AGCATGAGAAAAATAGTAGACAGTTCGTTTTGTTTTTTCCAGAAGAAAATGTTTTGTTGA GTATGCTTACACTTTTATTGGGTGTTCATAGTGAACTAGTTAGTTGAGGGCTTTAACATA GTTGTACTTAAAGGGCTGAGGGCACGGAAGAGGCATGGCAGGGCATGGCATGCTGGACCA AAGTGTTGCTAATGGTGGGTTGCAACCTATTCGTGTGTCAGGTGTTAGGTTAGTGCGTCG CAGCCAATAGTAAAATAACCCAACTAGGTTAAAAAAAAATAGAGTGTAAGGGCATTGTTT GTTATTAAATTTTTATTTTATATTTTTTGAGACAGAGTCTCACTCTGTCACCCAAGCTGG AGTGAAGTAGTGCAATTTCACCTCACTGTGACCTCCGCCTCCCGGGTTCAAGCGATTCTC CTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACACACCACCACGCCCAGCTTATTA TTATTATTATTATTTGAGATGGAGTTTTGCTCTTATTGCCCAGGCTGGAGTGCAATGGCG CAATCTCGGCTCACCGCAACCTCCACCTCCTGGGTTAAGCGATTGTCCTGGCTCAGCCTC CCGAGTAGCTGGGATTACAAGGCACCTGCCACCACGCCCGGCTAATTTTGTATTTTTAGT AGAGACAGTGTTTCTCCATGTTGGTCAGGCTGGTCTCGAGCTCCCGACCTCAGGTATTTC AGCCACTTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCTAGCCAGC TAATTTTTTTTTTTTTGTATTTTTAGTAGAGACAGGGTTTTACCATGTTGGCCAGGCTGG TCGTGAACTCCTGACCTCAAGTGATCTGCCTGCCATGGCCTCCCAAAGTGCTGGGATTAC AGGTGTGAGCCACCGCGCCTAGCCAGCCAATTTTTTTTTTTTTTGTATTTTTAGTAGAGA CAGGGTTTTACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCCTG CCATGGCCTCCCAAAGTGCTGGGATTACACGTGTGAGCCACCATGCCTGGCCAATATTTA ATTGATAGAATACTTTACATATTTATAGAGTACAGTATGATATTTCAATACAAGTATACC AGATGTAATGCTCCAAGTGAAGCGGCATCATTGTCTGGGGTAAATTCCTGAGGTTCGTTG TCTCATGCCAAGGAAATCAAGGACACGGACACACATGGAGTGAGGTTAAGAGCAGAGGTT TAATAGGCAAAAGAAAGAGAAAGGAGAACAGCTCCCTCTCCTACAAGAGAGACTTCCAGC CTGCAGTAGAGTGCACAGGGTTTTATAGACAGGCTTGAAGAAATGGTGTCTGATATACAT AGGGCCCGAAGATTGGTTGGACCAGGTGTGATGTTTACATAGCACGTGAAGAAGCTGGCC ACTCCACCCTAATCTTTTACTATGCAAATGGGGTCTCTACTTGGCCTGTGCCATGTTGCC TGCTTACTTACTGTGCACGTGGTTGACAAGGAAAGGGGAAGATGGAGCTGCCGTGTTGGA CCTACCTAGCCCCCAGGTGGTCTTTTCCTAGTGGCACAGTTGCTGGCATTCACCCATGCA AGCTTCCAGCTTGCTTGTCTATGTTTGCAGCTCGATTTTACTGGCTGCTCTTTGTTAGAC AAGAAAATGATTTGGGGGCTACTTTTCCTTAAAAGGAAAACCTTACTGAGGACTTCTTAC CCTTACTATCTGCCTAAATAGTATTCTCTTAACTCCTATATCACAAGCAGGGTAATTAGC ATATCCATCACCTCCAGCATTTATTATTCTTTGTGTTGGGAATATTAAAAATCCTCTCTT GTAGCTATTTGAAAATATATAATAAATTATATTTAACTGTAGTCACCCTACAGTGCTACA GAACACTAGGATTTATTCTTCCAATCTAGATCTTACCTTTGTAACTGTTAACCAACCTTT CTCTATACCACCGTCCCACACCACACCTTTCCCAGCCTCTAGTACTCATTGTTCTGTTCT CTACTTCTGTGAGATCAACTTTTTTCTCTTCCACATATGAGTGAGAACATGCAGTATTTA TCTTTCTGAACCTGGCTTATTTCAGTAAGGGTATTGTTTAGTAAAACTTTCATATGCGTC TGTTTATGTGCAAACATACACCTGTGCACAAATATATTAGTAGGTCATGATATAAAATGG ATGACAAAGGTTGTAGAACACTGTGCTAGGTGGTCAGCTCTCCAAAGGGTAAGGAGCACG TGGATTTTGTGAATCCGTCTATCCCTAACACTGTAACCAGTTCATAGTTGGCACTCAGTA AGTGTTTGTAGATTGAGCCCTCAACTCAATCATGGAAACAGTGGAACCACTAATACAGAT GGGAATGTATATCCCTAAGGTGTGTCATGTAGGAAAAAGATTTAGAATTATTGCCTTCCC AGATGAGTGATAATCACTGTTATGAAAATTATCCACTACTGATATCTTCCCTATAGACCC CTTAAGTAAAAAAATGTGGGACATGATTGTGACTAAACCTTCTTTAGTGGTTCTGAATAG TCCTAATGATGACTGCCTGCACTAATGAGGGAAGTGGAAGGAAACTTAGGGACAATGACC TGATCATTGTCATTCACAGGACACCTGAATGAGTGAAACTCCGGTGCCATTCTCAGTAAG CTTTTAAATGAGACTTAACAAGACACAGCCTCCTGGTAGACCTCCAGACTATAGTTGTTT TGGTTGTGGTTATTTTAATTAGTATTTATTTACATAATTAGCGATTATGTAAGTGGGTCC TACCATTTGTTGAAACCTCCTGGGGTCAGGCACTGTGCTAAATATTTTATGTACATAATC TTTTCAAATTATCAGTGAGTGATACCACCAAACTCTATGAGTGAGGTGGTAGTATTTTCA TTTTCGGATGAAGAAACTAAAGCCAGTAAAGGTAGGTTAGTTTGCCCATGGTTTTCCAGT TGGTAAGTAGCAGACCTCAAACCCAAATTCAGGTCTGTTTGTTTCCAGAACTCCAAATCA CTGTACTCAAATGCCCTTTCACACCCATACCTTCCATGGTGCTTTTCCCTATTCCAGGAA GTTCCATAATGTATAATAATATCTCTTCAGCAACCATTGCCAAGATTAGCTGATGATGCT CAGTCCAGTTTCATAATGTCTCAGTCCTTGCAGATTACAGAGATTACAGAGATTTGAAGG TAGGCTAAGGTTAGCATTTCTTGTAGACAACACCTCTTTTTTCAGGGGAAATTAGATTTT ACCGTTTAAAAAGATGAAACCACTCAAAGGTGTGTACATTTTTGAAAAGTGCTTGCCTCT GAATTTTACCTTGCTATTTCATGCCATGTGTTATTTCCTTAGGCAGAGACTTTTTGATAT GTCATTAAACAACTTTGAAAAAATGAATTTGGAAGGAAAATAAACCCAGAATATGTTATA AATTGCTTGTTGTGTTGGTTTTCTTTTACATGTATATGTGTGTGTGTGGTTTTTTTCTGT ATGTGTGGTTGAAATCTTCGAAAGTACTGTTTGTCACATACCTGAGGACCTGTGTATTTC TTCTGGGTAGAAAAATGTGTGGTTTTGTTGTTGTTGTTCTTGTTTTTGAGATAGGGACTT GCTCCTTTGCCCAGGCTGGAGTGCAGTGGCATGATCATAGCTCGGTGCAGCCTTGGCCTC CATGACTTAAGTGATCATCTCACCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCAAGC CACCATACCTGGCTAATGTTTAAATTTTTGTGGAGTTGGGGTCTCGCTGCATTACCCAGG CTGGTCTCAAACTCCTGGGCTCAAGCTATCCTCCCACCTCAGCCTCCCAAAGTATTAGGA TTACAGGCATGAGCCTCTGTGCCTACAGAATATTTTGTACTTAAAACTTTTGTATATATT ATTAAGATCATCACTTGGTGAATGCTAATCGAGGGCCAAGAGTAGAAATTCACCCAAAGA GTTGAATAAGTTGTATGCAATGTACCAATAGTCACTGTGGCTAGAGAGAGCATGGTCTAA ATAGGACCACTCAGAGGAGAACAGAGACCTGGGCCATTCCAGTTCTTGAAGATCCCAGTA TACTTCAACAATAAAAATTTTATAAAACGACTACTTTTAGATATTCAGTTTTTCAGTGCA TCTCTTTCTACATGAATAACTGTATTTGTAGATAGTGCCAAACATGCACATTTGAGATCC TTTTCGAATATGTATTTTCTCACACTCACAGACATACAGCGCACACATCATTTTACAGGT GAGACAGCTCATGTTCGGTGACCTATTAGCAAGACTGAGGACCTGAGCTTGGGTTCATTT CTTGATCTCCAGCTAGTTCCGCCTTCTTCTCTTCTGAAGGTCCCAGGTATTGGCTTGTTT GCTTATCTTATAACTGCTGCAAACTAGCTGTTCTTTCCAATCTTTTTTCTCTCTCTCCTG TACCAGGGTCAGAGAGGAAAATGGTCTCAGCTTTTCAGTTATCTTCTCAAGCCTAAATAA GCAAATATATCTGGTAGTTTTTTTTTTTGTTTTTTTTTTTTAAAGATATTTTCCCTTAAC TTAGAAATGAAACAAATTTTCAGTGGAATAGAGAGGTGAGAAAGTAAGTAAAAAAGTGAA AACATCAACAGAAAGACAAGCCAGAGACGGGGAGAAAATATTTGCAAAAGACACATCTGA TGAAGAACTGTTACTCAAAATATACAAAGAACTTTTTAAAACCTAACAATAAGAAAACAA CCTGATTTTAAAAGTGGGTCAAAGATCTTAACAGACACCTCACCAAAGAAGATATACAGA TGGCAAATAAGCATGTGAAAAGATCCTCAACATCATGTACCATTAGAGTTGCAAATTAGA ACCGTTAAGATATCACTACCTACCTGTTAGAATGGTTGAAATCCCAAACACTGACAACAC CAAATGCTGGTGAGAATGTGGAGCCATAGGAACTCTCATTCATTCTTGGTGGGAATGCAA AATGGTACAGCTACTTTGGAAGATGGTTTTGCAGTTTCTTGTAGAATTAAACATGCTGTT ACCATATGATGCAGCTGTCTCTCTCCTTGGCATTTATCCAGGGGAGTTGAAAACTTATGT CTGCACAAAAACCTGCACATGGAACAGAAGCTTATAGCAGCTTTATTTGTAATTATCAAA ACTCGGAAACAACCAAGATGTCCTTCAGTAGGTGAATGGATAAATGTGGTACGTTGACAC AATGAAATATTATTCAGTGCTAAAAAGATATGAGCTATCAAACTATGAAAGGGCATGGAG GATTCAATCTTAAATGCATTATACTAAGTGAAAGAAGCCAGTCTGGAAAGGCTACATACT TTATGATTTCAACTCTATGTCATTGTAGAAAAAGCAAAACTTTGGAGACAGTAAAAAGAT CAGTGGTTATCAGGGACTTCGTGGGAGGGAAAAATAGGCAGAGCACAGAGCATTCTTAGG GCAGTGAAATTATTCTGTATGATTTACAATGGTGACTATATGTCATTGTACATTTGTCAA GGCCCATAGAACAGGTTTTGAAGTTGATGTGATGTTGACAGTCCCCGGGGAGGCTGTGCC TGCGTATAGAAAGCAGCGTATGGGAATTCTCTGTACTTTCCACTTGATTTTGCTCTGAGC CGGAAACTGCCCTGAAAAATAAAGTCTATATTTAAAAGAATAGTCGTAGATACTAGACAC AGCATTTTTATCAGCATTTTAAAATATACTATATGCAAAGATAATATTATATGGTCAAGA ATAACTCCTTAATGTATAAATTTAAAAGCACCATGAAATCTCTTAAGAAACAATCAGAAG TTTTATAAAATTTTAAAAAAGGAAAGTGAGGAAAATGCCTAAATTAAACAGTAAAACACA CCCAGTTATTCAACACCAGGTGGCGACTGGACTGGGTCTGGATTTTTCTTAGCTTGCCTG ACTCTGTGACTGCTGCTCTCTGCTTTCTTGGGCTCCTTCTCCCTCAATCTTCCTGTTTCC AGAACAGATGCTTTTTATGTCCTCTTGCCTGTGGTGACATCCCAGGATCCCTTCCATCTG CAGTTTTTTCTTACCTGTTAAACTTTATGAGGAGGAAAGGAGAAAATATTGATTATTTAC CTGTTTTGTAATAGGCATTATAATAGATGCCTGTTGTAATCTCTTTTAATCCTCACAATA ACCCACATGAAGGAGTGTTATTCTCCCCATTATATATATTAATAACTAATGTGAAAGATG ATATAATTTGTTGAAGGCCAGTGAATTGTAAGTGATGTAGTTTGGATATAAACCTTGGTT TCAAAATTCAAGACACGGTAATCTGTCCATTCTGTAAGAAGCAAGCACATAAGTGCTAAT GATGAGTGTTTGGTCACACACAAAAAATAAAGATTTACTAACACATTTATTTAAGAAAAC TCAGACTTAAGCTACATTTGGTTCTTAAGTGTCTTCTTCAAAAAGAAAGGCAATCTTGGG TAATTCCTCACCTGACTTTTAGAAGTGTGCTAGACCTCTGTCTTTTAAAAATGTTCAGCC TACGTTTATTTTTATTATTCTTGTTCTTCATGGTATCTTTCTTTCCTTTTCTCCTTTTTT GAGATCCATTAAGGATTTTACTGTGATTTATAAACTTTCTTCTGGAATGGTGGTTCTCCA CCTGAGGTGATTTTATTCCACAGGGATCATTTGGCAATATCTGGAGACATTTTTCATTGT TACAGCTGGGAGAGGGTGCTACTGGCATCTAGAGGGTAGAGCCGAGGGCCGCTGCTAAAC ATCCTACCCTGCAGAAGACAGCCGCCTCAACACAAAATTATCTAGCACAAAACGCCAGTA GCTCAAGGTTGAGAAATGCTGAACTAGAGGTGTGGGCTTATTATCAGGATAGCATAGCAC TGGATTCCCATTAGAATCCATAGTGTCTTCATAGCACTGGATTCCCGTTAGAACATTTCA TGCAGCCTGGTGCTTCAATTACCTGGCTTCCCTTTTTGTAGCATTGGCATTAGAATATAG TTTAGTCTGACTACAGAAGGGAGAAAATACCTATGTAACAAAATAGGTGAACTGACAGAA TTTTGGTAAAAGAGATAAAACATAGTAGGGTGATAGGTCTACACATTTTAAAAGCCAGTT TGCAGTCAGTGTTGAATTTTATAGTTTAATTGTGCAATTTAAACTGTTTGTTTATTCTCC ATGAGTGTTTCACGTTATGCCTTTGTGCCTGCTTCAGTGCTGGGGGACAGACCTTCTACC CTCCTGGTTCATGTTGCCTCTGTCTTCCATTCCTCTTTGCTGGAATGTGTAGTTGTGGTA ACTGTGACAATTCCTAAGGTTTCTGACAGTTTTTGAACACCACAATGGTGCTGTAAATTC CTGTCTTGGCCAGGAGATGGACACCACATTTTGATGGTTTCTCAAACCGTGTGTGACCTT TTCCTGGTTTCTCTGTTCTGTCAGTCATGGCATGGCTGGACAGAATTCAGGGACATCTAT CAGGCCTCTCAGGAGCAATTAAATTATTTTCATGAAGGCAATTTGCAGTTGTAAACAATA TTGAAGACACTGTGTGGCATTTCTCATTAGCTAAAAAAAAAAAAAAAAAGATAGTGGCAA CAATACAGGATTATCTGACTCGATAATTAGCCAGGCATGGTGGCACACGCCTGTAATCCC AGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGTGAGCCAAG ATCTAACCACTGCACTGCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAA AGATTAAAAATAATAATTAGGAGGGAGAATAAACGACATCTTGGTTTTTTAAAAGTCCTT TTTATGCCATTAAAGTGTGGCTTGTGGTTTATTATTACATTTGTATGCAACCTTGGTACT GACATTTTTATCAAAAGATATTGGAGAGATTTCAGGAATGAGGAGTTACATTCCCTTTAT ATCTTGTTGCCAGAAATTACTCTTAAGCAAAATAAATTCTGCCTGAAATAAAAATAAAAT GAGAACACAGCATATGCGTGTTTTTGGCTCTGTGATCTATGCAAATAGTTATGTATTAAC TCATTAATTAAAATGGGCTTATTCTACACACACATTTCTACCATTGGATTTTTCTTCTTA AAAAATAAGCAGAGCAGAGTGGGGAGGCGGCAAGAGGACCTGTGGCAGGCCCTCTTCGGC CATCTCTCTGGCCTGGTTTCCCTCGGCGTGCCACTGTGTGCTCAGTCCAGCACCATGGGG AAGCGGGACAATCGGGTGGCCTATATGCACCCAATAGCAATGGCGAGATCAAGGGGTCCA ATCCAGTCTTCAGGGCCAACAATACAGGATTATCTGAATTGACCAAGGCCTACCTGGGAA GAAGTAAAAGAGCAACTAGAAAAGAAAAAGAAAGGTTCCAAGGCTTTGGCTGAATTTGAA GAAAAAATGAATGAGAACTGGAAGAAAGAACTGGAAAAACACAGGGAGAAATTGTTAACT GCAAGTGAGAGCTCATCCAAAAAAAAGACAGAGAAAGAAAAAAGAAAAGAAGAAATCTGA TAGGTATTCATCTTCTTCATCAAGCTCTGATTCTTCCAGCAATTCTTCTGATTCTGAAGA TGAGGATAAGAAACAAGGAAAATGAAGAAAGAAAAAGAAGAACCGTTCACATAAATCTTC TGAAAGCTCCATGTCAGAAACTGAATCAGACAGTAAGGATAGTTTAAAAAAGAAAAAGAA GTCAAAAGATGGAACTGAGAAAGAAAAGGATATTAAAGGACTCAGCAAAAAGAGAAAGAT GTATTCTGAAGATAAACCTTTATCATCTGAGTCCTTGTAAGAATCAGAGTATATTGAGGA GGTGCGAGCAAAAAAGAAGAAAAGCAGTGAAGAACGAGAAAAAGCAACAGAAAAAACAAA AAAGAATAAGAAGCATAAGAAACACAGTAAGAAGAAAAGGCTGTTAGTTCAAGTCCTGAC TCACCATAACATTAAGAAAAATCAGGATTCCCTTATAAAGAAAGTGCAATGTCTGAGGAA ATTTCAACTGTGAAAACTACAACATATTTACTAACATGCATGAATTTTCTTGTTTTTAGA ATTATTCCTGGACTATTCAGTAGCCACTCAGATGCTACTGTGTGAAAGGGCCATAAATGT TGCCTGCTGCTTGAACATCTATTTTTTTCTCTTCCAGTGCTTGATAACTCTGGGAGATAA TACACTGCAGTCATACTAGTGGTTAAGATATTTGGGAATAAAATTAATACTTTTGACTAG AAATGTCTAAGGATAAACCAACAGAAATTGAATCTGGATACATCTTTAAGATGTAATCAG AAATGACCAGATGACTCTAGTTAAAATTTTTGAAGGAGGGATTACATTAATATTTCAAAA CCCTTACTCTGTAAGATAAGTGTAGTTTAATTTTTTTCCCCTCGTATACTTTTATTTACC TGGGGAAGGAGCTTTTAGGGTTGGGGGGGTGGTTTGCTATCTCTTTAGCTAGCAGAATAG TGTGCCTTTGATCCTCACACATCCTGTATTATGAACACAGTAGCCATACTTCACGGGGAG GTCAGAGCTGGCTACCAGCAGTCTTGCCCTTTACTGAGCTTAGTGTCATCCTTGGATGCT GTCATATGCTGCTTTGAGTGAACCAGAGAAACAGCCATTTGCAGCATGAGAAAGCCCCAA AAGCTCTGGGATTTACCTCCACTTCAGTAATAATGAATATTTTTTAGCATTAGAATGTGT TAGGTCATTTGAATTAATTTTTACTACACTTTGGCTTGGGAGAGGAATTATTTTAAATAG ACACTGGTACTTTTCGAACTTGATAGCTAAAGATTCTAAAATGCATGTTTTATACTAAGT TTTAACCAGTCAGGAAAATTTTATGTAACCAGTGATAGTTTATTTTTTTGTATGAATTTT GTTTAGGCTACAATGTTTAGCTTTTGTTAACTCCTCACTCTTGCTGTCTTAAGTTCATTA CTATGTTTAATGGCGTACTTGCCAAGATATTTAGCATGTAAAAAGCAGGGTTTTGATTAA AAAAAAAAAAAAACAGCTTCATATTGAAGCTGAGACTTACAATAACAAGTTGAGTGGCAA GCCTGGTATGCTGTGTCTTATTGCCAGAATCTTAGTAAATGTAATGTTTTAAAAGTTTAT TGTCTTTGTATATTAATAACAAAGTATGACAAGTTAAGTTTAAATAAGAGTTAAAAAAAT AAGCAGAGAACTTCTTCTATATAAGCACGTAAACAGTAATACCATTATTTTTGTAGCTGC ATGAAATACCATTGCATGTATATGTAGGATATGGCTATAATATACATTTCAACAGATTTG ATGACATTGGGTTGTTTTCTCTTTTGTCTACAATGAATTTCAAATTTAGTTGCCTACTTT TACACATTTTTTATGTTGCGTAAATTCTTAAAAGTAGAATTTTTAGGTCACAGGATATGA GTAACTTTAATATTTTTTAGGATTGTCACCTTGTCCTTCCAAATGACTCTTGAACTCCTA CTAGGCAGGGGCTGGATTCTGGAAAGAGAAACAATTGTTCTTGCTCCTCTTTGCCAATAC TGTGCTTTCCTGTCCTAGGCCAATCTAAATGGTGGAAAAAAAAAACAACAACAAAAAAAC AAAAAAAACCTCATGTTGTCATATGCACTTTCTTAATAGAAAAGTTGAGCATTGTTTAAT CTGTTTGTGGAACACTTATTTATATCACTCTGTGAATTGTTTGCCCTTCCCTTTTGTTGG TTTATTCATATTCTTTCCCTATGTTAGTGAGTTGTTGTCTTAGTTCATTTTGGCTACTAT ACCAAAATACCTTAGCCTGAGTAATTTGTAAACAACAGAAATTTATTGCTTCCAGTTCTG GAGACTGGGAAGTGCAAGATCAAGGTGCTGGCAGATTTGGTGTCAGGGCCTGTTCCTCAT AGGTGGCACCTTCTATGTCTTCACATGGTAGAAGGGGCAAAAAACCTCCCTCACATCACT TTTATAAGGGCACTAATGCTATTTAGGAGGATGCAGCCCTTATGACTTAATCACCTTCCA AAGTCTCCACCTCTTAATACTGTCAGCATTGGGGGTAGGTTTCAACATAGGAATTTTGTG GGCATATAAACATTCAGACTGTAGCACTTGTTCATCTTTTTTTTCCTGGTAAAATTAGAC TTTTAAATTGTTTTTTCTATTGTTTGTCTTGCCCAAACTGTTCCCTCCTCGCCACCAATG CTTATTTACAAGTAATTGATGGATAATTTCTATATCAAACTAGAATGAAATGAATTGACC TTAAATACTAATAATGTGTTAATTTTTGAAGGACTATAGGAAAGTATGTATTAACATTAA GGCCATTGGATTTCCAAAATAAATTATCTAAAGACTAGGTCCTCAATATTAATAGCATGG AAATGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGTGCGCGCGTGCGCACGCCCGCGT GCTTATGGGTATGTGTGTGTGCGTGCATGTTTGCCCTGATATGAGAATTACTTACTGTAT TATACAATAGTCATTGAATTTCTGAGTTTTCTTGGTGTAACAGAAAGATGATACAATAAG TTGTTTGGTTTTATTTCTATGTGTTGGGATTTGAATTCTAATTTTAGGGTAAAATTTCTG AATTTTTTCTAATCCATTATATTCAAGGGAAGGAGGACATATAAACTTCAGTATGTTATT TTGAATTGGCTCATATTCCATTTCTACTTTGTCTCCATTTCTAGAATGGTATCCATATGT AAAAGTATTTAATTTTTGGTATGGTTTACTTTCTCTTTAACACTCAGTTTAATTAACTGA GAACAAAATTCACCTTCTGTGCTGTGCAACTTCAGAGGTGCCAAAATAGCACCTTATATT AAAAAATATCTTGGAAATATTTTTGAGTGCTTTGAATAAAGTTTTTCCAGCAACATTGAT TTATATTTTGTTCCTCAACTCATTATGCTACTTTACACCTGGGTTGTGTCTGCTATGGAA GGGCATCCTCCATCCTCCCTTTTCCAACTGGCCAACTCCTACTCATCCTCACACATCCAT CCCAGGTGGCATGTCTTCCTGGAAAGCTTCACACACACCTCCAGATGGAGCCTAACACTC TCTTTCTTGCACCAGCTCAGCACCTTATTCATGCTTACATTTGGGCACTTTTCTTTTTTT TTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGGATCTCGGCT CACTGCAAGCTCCGCCTCATTTGGGCACTTTTCATGCTTGTATTGCATCAGCCTAGACAT TTGCCTTTTCTTTGGACTTTGAGCTCATGGACCTATGTCAAAGACCAGTATGTCTTATTC CTTTCCATGTGCGCAGTGCCTGCCAGAAAGTTGGAGTGATAAATTATGAGTTAAAGTTTA CATTATCATTAGATTTAGGATAAATTTGAAGTTAATTCAACAGTTATTTAAGTTATTCTG TTATCTTTTGAATAACTTTTGAGAAAGTAAAAAATGGCCCTGGCAGCTGACAGGCCACAT AATGTTCCCAACTGAACATAAATACCTCTTGCAGAATATAAATAATCAGACAAGCCTACT TCTTGAGTATGTCTGAAACAAGACTGAGAAAGGACCCTTTCCAACTACAAAAGTAATTAA ACATCCCTCTCTTATGACTGACATGAATGATTGCTGCTTCTTTACCGATGATGACTCCAA CTCAGCTTTAATCCTCTGCTTTCTAGATTAAATTTGCCAAGATAATCAGTGAATTGTCCC TACCTCCTGACAGCTCCCAGTCCAAACCTGGCCTTTAGTTTCTTAAACCTTTCTTGGAAT CACCCAAAACAAACTGAAATAGTATCCTAAGTATCCACCAGTTTCTTAAAATTCTCCAGT TACTTTGGTGTACTCTTTCTTGCTGTCGTAAGTGAATGAAAGCTCAATTTATTTACTACA AGAGTGTTCCTGGTGGTCTTTGATTAGTGGGCACTAGAGTGAGTGTTGGAGTAATTTAAG AAAGAAACATTTATCTCAGTCTCTGCCCTTTGGATACTTAGAGTTTGCCTGGGGATTCTG GCCCTACTTGCTTTAAATAAACCTTTAAAGTGGCATTGTTTGCTGTCAAGACTAGAGTAG AGGAGAAGAGTGCAAGTCACAGCTAAGGAAAATATTCCTTAAGTATTGATAATTTCTAGT GTGGATCTCAAAGGGCTGGGGCATTCTGTGTGGGAAAGGCTGAGAGCTGGGGAGAATCAT TATGTGTTACAGGAAGAGAGGAGACTATTTTTTGAAAGGGAAAGTATTTGAAGACTTGGT GGCCAATAAGGTTGGACAGGTAGAGGAGATCGGTGACAGCCGGTGACCTTGTGAGAACTC ATCTACAGACAGTGAAAATCCCGGGGTTCGGGGTGGACACAGGAGATAATTAGTAGGAAG GGGTTAAAATACTGAAAGATGAGTATAGTAGGTCGTATTTGATGACAGGAGGATCAGAGA GTCTTTTTTGAAAGATGAGTCAGCAGGACATGGTAACTTGATAAGAGCAAGGAATTGGGT GGTGGGCTGCTGTAGCAGATGCTTTTGATATGGTCTTGGCCCACCTGTGAGTTCACCCAC AGTGGACATCTCCCATGCATGCCAACAGCTTTCCATCTCAAGGGCCTGATCTGTGCTTCT CTACCGGAGCACATTGTCAGCCCTGTGGAAATTTACTCTTGCTGCAGAGCAGCCTCGAAG TATAACCTTTACTCAGTGAAGGGCTGGAGTCAGAACACAAATGCCCATTTTCCCCTTCTC TTCGTGGGACAATTCTGAAGCACATTATTTATGTCTTTTCAGAACATCCTAGGGACATTG ACCCCCAGCAGGAATGTGGCATACCACCCCCTTCCATGGTTTTTCTCTCTCCCCAGTCAG GCTTTCCTCACTTCCTAACTTATGCTCCCTGGGATCACCTCCCCAGTTCACTATGCCAGA CTAACCAACCCAAGTTCTTATCTCAAGGTGACTTTTGGGGGAACCCAAACTAAGATGGGT ATCTTGGATAATTGGGTTAATTATTATGCCATGGAAAAATGGAATTGGGATTCTTTCCCA GGTTAATTAATGACTGCTGTCTAGTGAAAAAATGACTACAGTCATCTCAAGTGTATTTTA TATATCAGTGCAGGAATATGGCAAAATGCTTTAGAATTCGTGGCTTGTTTTGAGGAAAAA AAATATGCTCCAAACCATCTGCAAAAGTATTACAGTGATCTCAAGTGGAACATAGGCACT TGAAGCAGTTTCCAGGCACATTAGATTGTTGTCAACAAGAAGAAAAATATATGCCATGGG GAGGAGCAAGAAGAAAGAGAGGGTCTAGAAATCCATGATTTTAGCAAGTCAGGAAAAATA ATTTTCAGCACGTAAGCAGGGCAGGATCCCTGAGCTCCTTCACCTGGAAGTCATCCAGGT GGTTTAAGATTCTCAGGCTATTGGCAACTATGATGTGGCTCCTGCCAGGTTAAGGAGCAT TGATGATTGATCACAAGGGAAAGGACCCAGCCATATGATTGTTTCTGTCAGCTTGTACTC TCCTGAAAGTCATGGTTAATGACTTGAGCCAAGTTAGGAAAAATATTTCCGTTACTAACA ATATAGTTGTTAAGTATGCTCCATGGGGATTCTGAAATATTTACTTGACAGTAATGAGCT TTAGAATTTCATTCTTTTCCTATGATTCTTCATGATCACATTTGCATCCAGATCTTTGAA CACTCAGCACTTGATGGAGTTTAATAGACTAATGGCAAGAAAATTGCTCATAAGTAAAGG AAGCAGTGAATCCATCCGGTTTCCATGAGCAGTCATACCTGAGTTCTTCAGCAATTGGAA CAGATGCGTCACTGAAAAGATGCCTGCACTGGGGTGGTCCTATCCATTACATTCTCTTAG GAAATGAAGCCCTGGCTTTCCTTAGCCCTGTGATCTATTTTGAACCTTATTCTAGCGGAG AAGGAATAGTGTTTATTGATTTTTTTTCTCCTGTTGTCTATTATTTAGAGATTCTTAATT CTACTAAAATAAGTTGGGAGAACACATATTGTTTGTTTAGTATTTAATAAATTTTGGAGA ATCCATATAATCACTTTACAGTATTCTCATCAATCACATGAATTAAGTAATAAAATAATA AAACATTTGAATTCTTAGGAACATGTATTTTTTAATCAGAAAATATTCACCTCCGTGGTT AGCAAACCTCATATACAGGAAAATAAAATTAGGCCATGATCACGTTAGTTATCTCTGAGA GAGCACTTTTAGAAATAATAATCTAGAGGACAATGATCAGAAAAGGAAGAAGTAGCAACT AATACTTAAGGATACCTACCTATGAAAGAAGATGGTAATAGATAGGGTAGTTTCTTGGTG CATCAGTGGGTTGAGGTGAAATAAGTTTATTTTATAGTTTTGTTTTTGTTTCCTTTAAGA ATAAAGGAAGCTTATTTGAGTGAGCTTCTAGACTGAGGAAGTGTAGATTGACAATAGAGG AAATTAGAGGGTGGTGTTTAACCTGGAGCGACCCCTTGCAGGGGTAGATTTAAGGTAACA GGTGTTAAGGCTGTGGTTAACTAGTTTTGGGCTTGTTCACCTCACTTTGTGAATTCTTCC ACTGACACTTTGCTCATTTTATTGAAATAACTGATTTCAATTTCTGGTTTCTAGTCTTCA GTTCTGCTAGGTATGGTCTCAGACTTAATGATGAAAACTGTTGATTCTGCCAGACACATG CCCAATAAAATGCTTAGCTTTTAGCAGATCCTCAATAAATATTTATTAAAACTAATTTGA ACATATTTTCCTGAGTTTGGGAAGAAGGGAGTGAGACAAATAAAAATTATAATGTATTTG ATGTAAACTGGAGAAAATTCAGTGTAAATTCCCTCTACTTTCCTCAGTCTGTTTGGAGAT AAAGTCATCTCCTGGGAGAATAAGGGGATGGATTAGAGACTCGAAGACACTGGGGAGTGT TCAGAACAGCTGCTTATGGAAAATGCATGGAAAAAAATTAAAAACTTGCCAAGATGAACT GAATATCCAGCTGAGGCTGCATGGTATGAACTTGTTGAGTTTCTTAGGATAGTTCTATGC CTTTTTCTAGTTCTTTGGTCACTCAAAAGTGGAGAAAGCAGAGAGGGGTTATCTTTGGTG AGACGGGTATGGCAGAAAGCCTGAGGACTGGGGATTTTGGAGTGTTTGATAAAAAGATGA AATGTTCAGCTGAAGGTTGTGATGGCACAGAGAGAATTTCAAGCCAGCAGGAAGGCTAGA GAGGGCAGGGGCTGGAGTCATAATAAGCTAGAAAACTTATTATGTGTTCTCTAGCTTGTT GCCTGTGGGGTTGAGGACATTCAAGATTGTGTTGGTAGGAGGCTGTAGCCACAGAAGGAA TGATAGCTTAAAAATCTTAAGAGGTTGAGTGGTCTGGATTGTGATAAAGTGCAATTTACA GCTGGGCTTATGGGTTGCTAATGTGTAATTACTCTCACAATTTGGCAATTCTCAGCATCT TTAGGAGTGTTGTCTAGCAAAATTAAATTAGATTCTTTAAACAAGCAAAAAGAAACTTGT TAATGAATTACAACCAAGTAAGATGGAAACAGTTAGTGTCAACATGATGAGTTTGTGAGA TTCTATGTGACTTTAAGACTTTGAGCAGCCAAGCTAATGTTCAGTTCAAAGTAATTGAAT TTCATGTATGGAAGAATGCCTTATGAAACAGCCGATCAGTGCTTTTGCTAGCCAGTTTTG AAATGTTACATGTCCAAACACCTCATAACTTATGCATGTTCTCCAGTGAGAATTACATCA TAGGTTGAAAGAAAATAAATGCATCCATGATTCTTAGATGTTACATAATCTAAGCACTTA ATAACTTCCTAGTTACATAATCTGTAGTTATTATATAATCTCATGGCTCTTTACAAAGGG GGAAATCAAACTATTCTCAGAGAAATTCAATTGGATGATTGGATGAAAGAACTCTGTGTC TGTGTGTGTGTGTATATGTGTGTATGTGTGTGTGTGTGTAATTTTGCACATATACAAATA CTTAAGTGCTGGTTAGAATTGATCTGACCCTCTCCCTGACTGCTTTTCCCAGCCCACTCC AATGAACAACTGGGTCATCTTTCAGCTCCAGAACATTAAAAGTTGTGACCTGTGCCATCC CAGGACTATGTACAGGATTCCTTGGAGTCATAAGGAATGTTCTTCATTCTTCCAGCCATT TCACTCTGTTCCTGGCTTTTGGCTCTGCCCCAGTAGTTATGCTTAGCCCTACTTGCCCTG TCAGCAGCTCCTGAACCAGTTGCAGGTTCAGTTGGTGACTTCAAGATGGGGACACTGGCT TACAGACTGGCAGTCACCAGAACACATCTGTCCAGAGCCCCGGTTGCCCCGGTCCTGTTG AAACAGGCGCTGCACCTTCAGGTCTCTATTTTCCTTGCACCTCCGATTACTCATCATGGT GGAGTCTGGGTAAGAAGGAAGTTGAAGAGATGAAAGCAGATAGAGTTCCTGAGGATCTCA TTGCCAGTCGTGGCTGTCTATTCCCTCCCTTGGCAGCCCAGTGTCTCATTTGAGGTTAGA CACCTGTCTGGTGCAGATGTAAACTGATATACCTACCTCCCCATTTGCAGCAGGAATCTG GAGTCTCCTATGGCAATTTTGTGGGGGTTGATTTTGGGAGACTTTTATCTAGACATTTCT GCCTTGTTTAACGTGTGGCTTACTTTCCTGTTCTGTGCATGTTATTATGTATTACTGGCA TAATAACATGCACAGAATGCATGTTATTTCCTTTTGGAGCACATTGTTGCAAATATCGAT CATGCAAGACATGTACATTTGTGGCAGACTCTTAAATGTGTAAGGATGCAGTGAGGTTTT ACTTAGCCTGATCGTTCCATCTGTGACTTCCACTTCCTTGCCGTCCCTGCCCTACTACAA TTCCCAACTGCAGACTCTGCCCAGATGTAATTCAGCAAACATTTTAAAATACCAAATTTT CTCTCTACCTCTGTCTTGACTGTGGTCCTCATTGTGCTTCTTTCAAGTATGGATCATCTA GTCTCCATCCTTGTTTGTGAAGTTGTCCTGTCCTTCACATATTTTTAAGAGGGGAGAGGA GCAACGCGGAACTGTATTTCACCGCTAGAGTGAACATACCATATCAGAAGGCAGAAATGT GTATTTTTGTAATTACACAGCATGTGTTTTTGTCTGTGGGTTTGCTTATTTTGCAAACAA ATCCACATGGTTTACTTGCTAGTCTTCTTGAATTTTTCAGATGGTGAGCCTGTGGATCCT CATCTCATCCAAGATGACTTCCTGGCCACCTCAGGCCATGTTAAACAACCTGGAATGCTA GTATTACTACCAGCAGTGTCTGAGGGAGACATCCCAGAGGCTGATGGTTTTCTAGAATCA TGTTTTCAGGGAAAAGGGAATAATTTTTTTATGATGAAGTAAGTTCTTAAAAAATTGCCT TATTCTTTTGGTTAATGTTTCTTAACAGCTTTGTGGGGAATGGTTGCACACTTTATAAAG TTTCCTTTACAATTGGGGAACTTGGAGACCAACTTTAATGTTGATTGTTAAGGCTATTTC ACTTATAAAATTTAGCTAGCTGTTAAAAAATTTCTCTGCTGTATTTCTTATATCCACAAG GGATTAGAATCTATTGCTTTTGCAATGTAATTTTAATTAGACTGCAAATTCAATCATCTG ACTAACTCTTCCCTTGTCATTTAAAATTGTTTGCAAGCTTGAATGGGAAAAGTTAAAAAT GAGACCAGATAAGCATGTGCATTTTCATTCAGATAAGACTACCCACAATGGATTTAATCA TTTAACCAGTTTTAATAATAATAATAATAGTGAAAATTACATAATTTATTGAACACTCAC CTAGTCAGCTGTTGGATTTTACATGTCTTATAATTTATCTCATTCTTCTGAATAGCTATT CAATGAGATGAGCATCGCATCTCAAAGTCGAGAACAGGCTTAGAGAAGTTAAAGGAACTT CATATGTTTCCATTAACTTGTAGGTTCTTTGGCTGGGATTTGCACCTACAGTTCATCCAT CTGGGCAACCCATCATCTTCACAGTGCTTAGAGCTTCTAGAATAGGACCCTGGCACTGCC GTTGTATACTCAAGTATCACATGTATATTTTTAAGCACTTTAATTGTTAAGTCTTTCTGA TTTCAACAGGTAATGTTGCTATTATATGTCATGCACAAATAGGAGACAGCTGTTAGGCCT CCATCCATCCTGTGTCTGTTACTTACATACTGAAAAGAAATCAGCTGGTTGTGTTTTATT TGGGAGTGACTGGAATTGATCTGTGCCCATTTTTGTGTGTGATCATCTTAAAAATATATC TGTTACTATGGAATGTTCTGCAGTCACTTCTTAAGGTTGAATACACAGTTGATGGGAAAT ATCTTTTAATCTACATACAAAGGAGGAAGTTTACCACAGTGAAATTCAGACGTATAGACT GTTGTTGTACAAAATGGAACTTTTTCCTCCTAGAATTTGGCAGACTTTTGAGTCCAGGAG GAGGAGGGGTATATAGGTGGATGGAAGATTGAGGAAACATGAAGTTGCTTTAGAAATGTA AGGAGTTGATTAAAAAGTAAGTATAGATGCTTATTTTACAGAGCTTTGTAACTTTGTCTC ACTAATGTTAACATTGGCCTTTAAAAAATGATAGAATTTAGTGTTGCTCTTTTCTTTACA AAGAAAACTATACCATAGAAAATGGAATTTTCTAGGGGACAGTAAGAAAATAATATATAT ATGATTTAAATTCTTTATTTTATTCATTTAATTCTCTTTGAGAAAACTTAGTGCATATGT ATCCAAAGTCTGTAACCAGATTGTTAAGTTAAAAAATGGTTTTCAGGCTGCGCACAATGG CTCATGCCTATAGTCCCAGTACTTTGGGAGGCTGAGGTGGGCAGATCACTTGAGCCCAGG AGTTCGAGACCAGCCTGTGTACCATGGTGCAACCCCATTTCTACTAAAAATATAGAAATT AGCAGAGTGTGGTAGTGTGTGCCTGCAGTCCCAGCTACTTGGGAGGCTGAGGCAGGGGAA TCACTTAAGCTCGGGAGACTGAGGCTACAGTGAGCCAAGATCATGCCACTGTTCTCCAGC CTGGGTAACAGAGCAAGATGCTGTCTCAACAACAAAAAAAAGGTGGGGTGGGGTGGGGGC GGTTCATACTTAAGAATTACAAAAGGATTTCTGGCAAAGTTGTACTAAAAAATAGATTTC TTTTTGTATTGAAAATATAATCTTTAGAAACTGGATTTATATTCCTTTAGCAGCAAACCT GATTAATGTCAGTTAATAGCTTCTTCTTAATCAAGTACAGACATACCTTGGAGACACTGC AGGTTTAGTTCCAGACTACCTCAATAAAGCAAATACCTCATTAAAGTGAGTCACACACAT TTTTAGTTTACCAATGCATATAAAAGATATGTTTACATTACATGGTAGTTGATTAAGTGT GCAATAGCATTGTGTCTTTAAAAAATGTACATACTTTAATTAAAAAACCTTTTTTGCTAA AAAATGCTAGTGATCATCTGAGCTTTCAGTGAGTCTTAATCTTTTTGCTGGTGGAGGGTC TTACCTCAGTGTTGATGGCTACTGATTGATCAGAATGATGGTTGCTGAAGGTTAGGATGG CTGTGGCAATTTCTTACGAAAGTCAACAATGAAGTTTGCCCCATCAATGGACTCTTCCTT CCATGAAAGATTTCTCTGTAGCATGTGATGCTGTCTAATAGCATTTTATTCAGAGTAGAA CTTCTTTTACAATTGTCATCAATCCTCTGAAACTCTGCCACTGCTTTATCAACTAAGTTT ATATAGTATTATACATTTTTGGTTTTCATTTCAACAATCTTTGTAGCATCTTCATCAGAA GACAAAGAACCCATGTTCTTTGCTTATCCATTAGAAGCAATGTCTCATCCACTCAAGTTT TATCCTGAGATTGCAGAAATTCATTTATATCTTTAGGCTTAACTTCTAATTACAGTTCTC TTGCTGTTTTCACCACCACTGCAGCTACTCTCTTTACTGAAGTCTTGAACCCCCTCAAAG TCATCCATGAGAGTTGAAATCAACTTCTTCCAAACTCCCGTTATAATTGCTATTTTGACC TCCTCCTATGAATCATGAATGATACATAGAATAATACATCCTTTCCAGAGGTTTTCAATT TACTTTGCCGCAATCCATCAGAGGAATAACTGTGTCAGCTATAGTCTTACAAAATGTATT TCTTAAATAATAATAATAATAATACTTGAAAGTCATAATTACTCCTCTATCCATGGGGTA CAGAAGGAATATTGTGTTAGCAGGCGTAAAAACATTAATCTTTTTGTACATCTTCATCAG ACCTCTTTTGTGACCAGGTGCATTGTCAATGAGCAGTAATATTTTGTTTTTTATTTTAAT ATTAAAAAAAGGAATCTTTTTTTTCTGAGCAGTAAGTCTCAACAGTGGGCTTAAAATATT CAGCAAATCATACTGCAAACACATGTGCTGTCATCCAGACTTTGTTACATTTATAGAGAA CAGGCAGAGTAGATTTAGCATAATTCTTGAGGATTCTGGGATTTTGGGAATGGTAAATGA TCATTGGCTTCGACTTGTAGTCACCAGCTGCATTATCCCCTGTCAAGAGCATCAGTCTGT CTTTGAAAGCTTTGAAGGCAGACACTGACTTCTCCTTTCTAGCTAGGAAAGTTCTAGATG ACACCTTTTTTTCCAACAGAAGGCTGTTTTGTCTACGTTGAAAATTTGTTGTTCAGTGTA GTCACCTTCATCAATTTTCATAGCTAGATCTTCTGGATAACTTGCTACAGCTTCTACATC AGCACTTGCTGCTTCACCTTGCATTTTAAAATTATGGAGATGGCATCTTTTCTTAAACTT TATGAACCTGTCAGTCTTAGCCTCCAACTTTTCTTCTTTAGCTTCCTTACCTCTCTCAGC CTTTAGAAAATTGAAGAGAGTTAGGGCTTTGCTCTGGATTAGGCTTTGTTGTGGCTTCTT ACATTTTCTATTCAGATCACTAAAACTTTCTTCATATCAGCAATAAGGCTTGTGTTTGTT CCCACACAGCTTTAAAGAAATACCTGAGACTGGGTAATTTATAAAGAAAAGAGGTTTAAT TGGCTCATGATTCCACAGGTTTTACAGAAGGTATGGTGGCATCTCCTTCTGGGGAGGCCT CAGGGAGCTTTTACTCATGGTGAAGGCCAAGTGGTAGCAGCCATCTTACATGACAGAAGC AGGATGAAGAGAGTGAAAGAGGCAGAGGTGCTACACACTTTTAAACAACCACATCTCGCA AGAATTCACTCACTATTGTGACGACAGTACCAAGGGGGACGCTGTTAAATCATCCATGAA GAATCCACCCAATGGTCCAGTTGCCTCCCACCAGGCCCCACCTCCAACATTGGAGATTAC AATTCAACATGAGGTTTTGTGAGGACACAGATTTAAACCATATCTTTCTCCCCTGACCCC ACAGATCTCATATCCTTCTCACATTGCAAAATACAATCATGCCTTCCCAACAGTCCCCCA AGTCTTAACTCATTCAGCATTAACTAAGATGTCCAAAGTCTCAGGTCTCATTTGAGACAA GGCAAGTCCCTTCTGCCCATGAGCCTGTAAAATCAAAAACAAGTTAGTTACTTCCAAGAT ACAATGAAGGTATAGGCATTAGGTAAAATACTCCAGTTCCAAAAGGTAGAAAACAGCAAA AAAGGGGGTTACAGGCACTATGCAAGTCAGAAACCCAGCAGGACAGTCATTAAATCTTAA AGCTCCAAACAAAATAATCTCCTTTGACTTCATGTCCCACATCCAGGGCACACTGGCATG AGAGGTGAGCTCCCAAGGTCTTGGGGAGCTCTACTCCTGTGGCCTTGTGGGGTTTAGCCC CTGTGGCTACTGTCATGGGCTGGCATTGAGTGCCTGTGGCTTTTCCAGTGCAGGGTGCAA GTTGCCAGTGGTTTACCCTTCCAAGGTTTGGAGGACAGTGGCCTTCTACTCACAGCTCCA CTAGGCAGTGCCCCAGTTGGGACTCTGTGTGGGAGCCCCAACCCCACATTTCTCCTCCAC ACTACCCTATTAGAGGTTCTCAGTGAGGGCTCTGCCCCTGTAGCAGGCTTCTGCTTGGAC ATCTAGGCTTTTTCATATATCCTCTAAAATCTAGGCAGAGGCTCCCAAGCCTCAGTCTTT CTTTCTGTGTCCCTGTGATCTTAACACAGTGTAGAAACCACCAATGCTTCTAGCCTGCAC CTTCTGAAGCAGAGTCCTGAGTGGTACCTTTGCTCTTTTGAGTCAGGGCTGCAGCTGGGG CAACAGGGATACTGGGAGCAGTGTTCTAAGGCTGTGCGGGGTTGCAGGGCCCTTGGCCTG GCCCAGGAAACCATTCAGCCCCCCTAGGCCTCCCTGCCTATGATGGGAGATTATGCAAAT TCCTGCAGCCTGCTTGAATTCCTCCTTTGAAAATGGGCTTTTCTTTTCTAACACAGAAGC AGGCTGCAAATTTTTCCAAACTTTTATGTTGTGCTTCCCTTTTAAATAAGAGTACCAGTT TCAGATAACATCTTTGCTCATGCATATGAGCATATGTTATTAGAAGCAGTCAGGCTATAT ACTTGAATGTTTTGCTGCTTAGAAACTTTTTTTACCAGATACTCTAAATCATCTCTCACA AGTTTAAAGTTCCACAGATCCCTAGAGCAGGAGAACAACCAGGCAAGCTTTTTGCTAAAG CATAACAAAAGTGACTGCTGGAGTTCCCAAAAAGTTCCTCATCTCCGTCTGAGACCTCCT CAGCCCGGACTTCACTGTCTATGTCACTACCAGCGTTTTAGTTACAACCACTCAATAAGT CTCTAGGAAGTTCCAAACTTCCCTTCATCTTCCCCCTCATCTTCCTGTCTTCTTCTGAGC CCCCCATACTCTTTGAACCTCTTCCTATTACCCAGTTCCAATGTTGCTTCCACATTTTCA GGTATCTTTGTATTAATACCCCACTCCTGGTAGCAGTTTTCTGTATTAGTCTGTTCTTGC ACTGTTATAATAAAAAAATACATGAAACTGAGTAATTATTAAAGAAAAGAGGCTTAATTG TCTTGTGGTTGACAGGCTGTGTAGGAAGCTTGGCAGCATCTGCCTCTGGGGAGGCCTCAG GAAGCTTGTACTCATGGCGGAAGGCAAAGTGGGAGCAGGTGTCTTACATGGGAGGAGCAG GACAAGGGGAGAGAGAGAGAGAGAGAGAGAGAGGGAGGGAGTGGGGGAGAGATGCTACAC ACTTTTAAACAATCAGATCTCTCAAAAACTCACTCATTGTTGTCATGACAGTACCAAGAG GGATGGTGTTAAACCGTTCATGAAGGATCCACCTGAATGATCCAATCACCTCCCACCAGG CCTTACCTCCAACATTGGAGATTACAATTCAAAATGAGATTTTGTGGGAACACAGATCCA AATCATATCAAGGCTATTTCTCTTTCTTATCATTTGTGCGTTCACTGGAGTGGCACTTTT CATTTCCTTCAAGAACTTTTCATTTGCATTCATAACTTGGCCAACTGTTTGGTTTAAGAG GCTTAGCTTTTGGCCTGTTTTGGCTTTCAACATGCCTTGTTTACTAAGCTTAATCATTTC TAGCTTTTCATTTAATGTGAGAGGTGTGTGAATCTTCCTTCTGCTTGAACATTTAGAAGC CATTGTAGGGTTATTAATTGTCCTAATTTTAGTATTGTTCTTTCTTAGGGAATAAGGAGG CCCAAGGCGGCGGGTGGGGATGGGGAGAGAGAGAGAGAGAGAGAAAGAAGGAGAAGAGAG GAAAGAGAGAGGAGAAGAGGAGAGAGAGAGAGAAAGAAGAGGAAGAGGAGTGTATGTGTG TGTGTGTGTGTGTGTGTATGTATATATATATATATATATATATATATATATATATATATA TATATATATATATATATATATACTGGTCAGTGGAGCAATCAGAACACATACATCATTTGT CAGTTAAGTTTGCCTTCTCAGCCAGGCACATTGGCTCACACCTGTAATCCCAGAACTCTG GGAGGCTGAGGCAGGAGGATTCTTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATG GTGAAACCCTGTCTCTACAAAAAATATGAAAATTAGCCGTGTGTAGTGATGCACATCTGT AGTCCCAACTACTTGGGAGCCTGAGGTGGGAGGATTGCTTGAGCCCAGGAGGTCGAGGCT GCAGTGAGCTGTATTTTGCACCACTGCATTCCAGCCTGTGCAACAGAGTGAGACCTTGCC TCACACACACACACAAAATTGCTGTCTTATGTGGTTTGGTTTGTGATGCTCCGAAACAAT TTACAATAGTAACATCTTCTGATCACAGATCACCATAACAAATATAATAATAATGGAAAA GTTTGAAATATTGCAGGAATTACCAAAACATGACACAGAAACACAAAGTGAGCACATTGC TTTTGGAAAAATGGCACTGACAGACTTGCTTGATGCACGATTTCCACAAACCTTAAATTT GTTTAAAAAAAAAGCCCCCAAACAAAAAATACAGTATCTATAAAGCATAATAAAGCAAAG CACAATAAAATGAGGTATGCTTGTAATATTTATCACTGTTACTGTGTAGGGAGATTAAAC ATGATTGTAGCTAATAAAACATGATTTTGTAAACACCTGTAACTCTAATTTCCATGAATC TCTAAAAATAGAACTTTGTGAAACAATCACTAGCCCTTGAGGCAATACCTAGTGCATAGT AGGTGTTCAAAACTTTTTGTGAGTGAGTGAATGAATAATGAATGGAAGCGTTTGTGATTA TGTGAGCTTTAACATGTCCTTTCACTGCCAATGCAATTTCTTGTGATTCTAATCTGTAAA AAAAGTATTCCTCTCTTACTATTCCCTGTTGCCTTACTTGGGTATACTTAGCTTTATGCT CAGAGAACACACTTGCTTAAAACTAGAGTAATAATCACAGGTACAATGTCCCCAATACAT TTCTGTGGAAATTTTTGTAATCTGGGTTGCATTGGTAGTAACCAAGTTTCATCTAGGGTA GCTACAGCACCTCAGATACTCTCCTTCACCAGTGCCATCTGCTCAAGCCTGTTTCTATGG TTTGCTGTTGATGCAGCTGTTGGAGCTACTCTCTTGGTCACTTGCTTACCCGGCTTCTGA GATTCCTCTAAAAATCAATCACATGGCTAATTGGCTGCTGCTGTTGATCAGGGCCAGTTG GCCTAGCATCATAAATGCATTGCTGGTTGGCATTGATAGTCTTGGAAGTGGTTTTCTTTC TGATATAAGTCTCTTTCACTCTAGTATAGGATAGTAGTTAGGAGCATGGTGTCTTGATGC AGAACTATGAATGTTGTCCTGGGTCAGCCAGTTACTAGTTGTAATTTGAAATTATGGGCA AGTTATTGTACCTCACTGTAAACATCTCAGATTTCTAATCTGTTAAATGGAAAGACAAGT AGTAGCCACCTCTTAAGGGATTTGTATTGATCTCTGCCCTAGGTAGTGTAACATACACTT CCATCTGTGGGAAAAGTCTGTGACTGTTGTCACTAACCTGCACAGGGATCTGGGCAAAAA TGAGGAAGACTTTAACACAAAGCTGGGACTGTGTTTAAGATCTGCCACCCTGCCTCTGAT TATCTTCACCTAGTGGAGGGTGAGCACCCCCTCTCTGTGACTTGCCGACTTGGCAAGGAT TTTAGGTCACTGTTTCTACCCAGATGCCAGTATCCAATTAAACTCTTGAGAGTCTGTGAT CATTATGATAAAAATGTTCATTCTGGAAAAGTTTGAAAATGCTTTCTGGTTAGAATGAGA TTTTTGGCATGTTTTAATTGTGGTCTTTGGCTATAAATTCCTGAAATGCTGACATGGTTG AATTTATTTTTGCTTTAAACAAAATCGTTAACATTTCCAAGTGTCCATATGAGCTCGATA AATACTTTGCCTCTGCTTACTGCGTATGTGAACCGAGTGAAGAGGAGCCATCATGATGTG GGGAATCTTGAACATTTTTCTTCATTTAGCTTGATGGGGAAGTGAATTGAAAATACTTCT TTGTCAACATAATTTTGGGGTTTTGAAATTGTGTTTGGGTTTTCAGGAAATTGGTGGTAA TCTTGTATTAGCTGAAAAAAAGTGAATTTTAAAATTCTCAGTGAAGAAGCAAATGATTTA TTTTTCATAGAAGAAGCTGCTTTTTTCAAGGGAATTTGCTGCCAAGCTGTCTGCAGTGGC TTCAGACATTACTTGACCTTTTGGCATATCAAGAAATTGTGGTTTTTTGGTCTAAATATT AAATACCTATTTTAGGAAGGCTGGGTACTCTATGGTATATAGTGCAAGAGCAGCAGAAAG AGTCAGCCTTGTGCATTTCCACATCTGCAAGCAAATTTGGTTTCTGTACTGTCCATCAAG CAGATCTTACAGAATGAATTTTCATCCCCTCACTAGTTGCCATGCAAATTCTATTAATAG TTCTCCAAGAAATAAATCACAGTGACCCTTCTGACAAAGGTAGACAGTGAAAAATAGTAC AAGGATATAGTACATCCACCCTTAACCAGAAGCAAATTGTGTTTTCCCTTTTTATACTAC AAAAAGAGAAAACAATTTACAAAAACAGTTTCTTCCACACATGTGTTATCTATGATGTGA TAGACTGTTCTTTTCATAGCCCTTTTCTGTTTTGGTGACTGCAACGGGGTATTATTTGGA ACATGTAGTCTTCTGTTTGGACACCATACTCGGGCTGTTTTTCTTCTCGCAGCCTGTGCT GCTGGAAATATTCCCCCGTCTCATAGCCATCATAAGTAAAGGACACCTTCCACTGCGACA TGCTGCATGCTGTTAAAGCCCTTCGATGCCAGCCAAATGTTACACCGTGCCTTCCAGGAT ATCTTTAATTAAACCCTTATATATGCATTTATAACCATCTGATGAGGGGATTAATATTAC TTGTGCTTAACAAATGTGTTAATTGAGAAAGGAAAAAGAATACAAAATAAACATTTTTAA GTACCTTCCCTATCGTAGTCACTGGGCTAAGTTCACAGCCACCTTGCCAGGCAGAAGTTA CCATCCCCATTTATGATTGGGAACTGAAACTTGAGGCACTTTTGGGAAACTCTTCAACTG ATTATTCGATCGTGTGAAACTGAAGCCCATGTGCAACATCAGCTGCCTCCCTGAGTTTCA CAGTGAAATGTGAAATATTTAAGATCCTCAGTGAATATTGTTGAATGTGAAAGATATTTA CTAAATTGTAATCAGTTTCTCAAACTATGTTCTTTATACTACAAGGTAACTGGATTAAAA TGGACTTTCCATAGGTACCTCATTCTTAGCTCGACCCCAAATAAACTTGGGATCTCCTCC TAAAATTGTCCCCACTTCAGTGTTCCCATCTCACATGCTCCAGCCAGAATTGCAGGAGTT TCCCTTGAGCCCCATTTCCCTTTCTCTTTCCATGTTTTATCAGGCAAAAAAGTATCACGA TTACCTACGAAGCATCACTGCCAATTGCAGGGGTGCCTGAGAGAGCAGCAGGACAGAGCC CAGTGCAGCCCCACAATTCAGACCTGACACCTGTGGAAGGAGATGTGTGTATTGGGGCAG GGGATGAAATGGAGCAAGATGGGGACAGGAGAGCTTCAGACTGTGATGCAGATCAGTTCT ATGTGGTCAATAAGTAAATCTGCATATTATCATTATATTACAATACACTAGCCACTGGAG ATGCAGTGGGATATACCACCTTATGTAATGATAATAAGGGACACCCAACAAATAGCTGAT GACTCACTAAAATGAGCAGTACAAATTTTATTTTGTTTATCAAATGTTTCTTCTCTCAGA AAAAACAACATATGTAGAATTTTGTGATTAAATTTGATGCTTGTTTTAATTACTACCACA TTTAATATAGTGTGCTGTTTTTCCTTGCACTTAGTCTTTTTGTGAAAAATCAAGTACCAA ATATCTAAGGTGAGTCATCAGAGGTAAAAAGATTGGTCCTTCTGGAGTACTTGTGACCGA CTCATTTCATGAGATTTAAGAAACACTGTAATGCCGTCTTTCCATTGGGTATCTCCATGA TTTATTGATATGTTTTTAGAAAATGAAAACAAGTAAACAAATTTTAAAGTTATCCCCACT CTTATTGAAGAAAGTCTGTGTATAAAAATACATATGTATTTAAAAGTAGTTAAAGTCATT GTATGTTATCAAATTCTTGTATTACCAGAAGACTTACTAAAGAACAGTAGTCTTTGTGAT TACCTAATACTGGATGGAGAGGTGAGCTGAGTAGTGCTAGGGGAATCTAAATCTAAATTA TTTGTCGTATTCAGCCAGGATGAGAAACGTTGATTTGATTGAACAAATAAAGAAAATAGA ACTAATTTTATTTTATTTTATTTTATTTTTTTGTCTGGGGCATAGAAATTTTATTTTCAC AAAAGTATGCTTTATTACACTAGAATATTTAAAAATGAAATACTATATATGTCAACATTT GAAAAAAAATTTTTTTTGAGACAGTCATTTAATATCATCTTTATTTTGTACTTTCTGTGA TTTTTTAAAATTATACTTTAAGTTTTAGGGTACATGTGTACAACGTGCAGGTTTGTTACA TATATATACACATGTGCCATGTTGGTGTGCTGCACCCATTAACTCGTCATTTAACATTAG GTATATCTCCCAATGCTATCCCTCTCCCTTCCCCCCACCGCACAACAGTCCCTGGTGTGT GATATTCCCCTTCCTGTGTCCATGTGTTCTCATTGTTCAATCCCCACCTATGAGTGAGAA CATGCGGTGTTTGGTTTTTTGTCCTTGCGATAGTTTGCTGAGAATGATGGTTTCCAGCTT CATCCATGTCCCTGCAAAGCACATGAACTCATCCTTCTTTATGGCTGCATAGTATTCCAT GGTGTATATGTGCAACATTTTCTTAATTCAGTCTATCATTGATGGACATTTGGGTTGGTT CCAAGTCTTCGCTATTGTGAATAGTGCCACAATAAACATAGGTGTGCATGTGTCTTTATA GCAGCATGATTTATATTCCTTTGGGTATATACCCAGCAATGGGATGGCTGGGTCAAATGG TATTTCTAGTTCTAGATCCCTGAGGAATCGCCACACTGTCTTCCACAATGGTCGAACTAG TTTACAGTACCACCAATGGTGCTATTTCTCCACATCCTCCCCAGCACCTGTTGTTTCCTG ACTTTTTAATGATCACCATTCTAACTGGTGTAAGGTGGTATCTCATTTTGGTTTTGATTT GCATTTCTCTGATGGACAGTGATGATGAGCATTTTTTCATGTGTCTTTTGGCTGCATAAA TGTCTTCTTTTGAGAAGTGTCTGTTCATATCCTTCGCCCACTTGTTGGTGGGGTTGTTTG ATTTTTTCTTGTAAATTGGTTTGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGTCAG ATGAGTAGATTGCGAAAATGTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGGTAG TTTCTTTTGCTGTGCAGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCAATTTTGGCTT TTGTTGCCATTGCTTTTGGTGTTTTAGACATGAAGTCCTTGACCATGCCTGTGTCCTGAA TGGTATTGCCTAGGTTTTCTTCTAGGGTTTTTATGGTTTTAGGTCTAACAATTAAGTCTT TAATCCATCTTGAATTGATTTTTGTATAAGATGTAAGGAAGGGATCCAGTTTCAGCTTTC TCCATAAGGCTAGCCAGTTTTCCCAGCACCATTTATTAAATAGGGAACCTTTCCCCATTT CTTGTTTTTGTCAGATTTGTCAAAGATCAGATAGTTGTAGATATGCGGCATTGTTTCTGA GGGCTCTGTTCTGTTCCATTGGTCTATATCTCTGTGTTGGTGCCAGTACCATGCTGTTTT GGTTACTGTAGCCTTGTAGTGTAGTTTGAAGCCAGGTAGCATGATGCCTCCAGCTTTGTT CTTTTGGCTTAGGATTGACTTGGCAATGCAGGCTCTTTTTTGGTTCCATATGAACTTTAA AGTAGTTTTTTCCAATTCTGTGAAGAAAGTCATTGGTAGCTTGATGGGGATGGCATTGAA TCTATAAATTACCTGGGGCAGTATGGCCATTTTCACGATATTGATTCTTCCTACCCATGA GCATGGAATGTTCTTCCATTTGTTTGTATCCTCTTTGATTTCATTGAGCAGTGGTTTGTA GTTCTCCTTGAAGAGGTCCTTCACATCTCTTGTAAGTTGGATTCCTAGGTATTTTATTCT CTTTGAAGCAATTGTGAATGGGAGTTCACTCATGATTTGGCTCTCTGTCTGTTATTGGTG TATAAGAATGCTTGTGATTTTTGCACATTGATTTTGTATCCTGAGACTTTGCTGAATTTG CTTATCAGCTTAAGGAGATTTGGGGCTGAGACAGTGGGGTTTTCTAGATATATAATCATG TCATCTGCAAACAGGGACAATTTGACTTCCTCTTTTCCTAATTGAATACCCTTTATTTCC TTCTCTTGCCTAATTGCCCTGGCCAGAACTTCCAACACTATGTTGAATGGGAGTGGTGAG AGAGGGCATCCCTGTCTTGTGCCAGTTTTCAAAGGGAATGCTTCCAGTTTTCCATTCAAT ATGATATTGGCTGTGGGTTTGTCATAGATAGCTCTTATTATTTTGAGATGCGTCCCATCA ATACCTAATTTATTGAGAGTTTTTATCATGAAGGGCTGTTGTATTTTGTCAAAGGCCTTT TCTGCGTCTATTGAGATAATCATATGGTTTTTGTCTTTGGTTCTGTTTATATGCTGGATT ACATTTATTGATTTGTGTATGTTGAACCAGCCTTGCATCCCAGGGATGAAGCCAACTTGA TCATGGTGGATAAGCTTTTTGATGTGCTGCTGTATTCGGTTTGCCAGTATTTTCTTGAGG ATTTTTGCATCGATGGAGCTGATTTTATAAAACTTTAGTTTAATTTTTTTTTTACTTTCC TTCCAGATCTAATTTCTCTCCAACAATTCTTACATGGAAGTATAATATTTTTCTCCTCAT TTGTTCTTGAGCTATTATAGATAAATTTTAACTGAACACTTTTGTTGTTAGAACCGATCT AACTTGGGTTTACTGTTTTGTCAAATTAAAAATCAAAATCTATATATAGATATATGTACA CATATCCCTTCCTCTAGAAAATTGGTAGTTTTTCCCTCTGTTAGGAAATAAAAAATATTT TAATAATATCACTTATCAGTTTGGGAAATTAGTATATAAATCTTAGATGAATGGCTTATA TCTCCACTGGTCAAAGAAGGTTGCCCCTTTGAATTTGACAGTTGGAACAAGTCTTTATTT ACTCTATAGAGAAGTCATCTAATCTGTTTAGCTTTTTGGTAATAGACTTTAGCTTATAGA ATATATACATGACCTTGTGGGTCAGATTGTCTGTATTTGAGTCCTTGCTTGATGATGTCT AGCTGGGTTTACTTAATCTTTTTGATCAGTTTCCTTATATGTAAAACAAGAATAATGGTT CCTACTTCATAGGATGGCTGTGGGATTTAAATGCAGGAACCTGCAGGAAGTGCCTGGAGT AGTCCTGGCACTAGGCTCCCAGGGAATGGTAGCTATTACTATGACCAGTGCATGGAAATA ACGTGTGTTTTTATTTCCCAAATTCAAAGTTAATTTTTGAAATGAAGGTTTATTTCCCTG TTGAATTCTAAAAGATTTGCACATGTATAAAGAAAAGACGATTATAATTTAGAAATTATA TTTTGGAAACTTATCAGAGTCTTAAGGTTTTGTGCTGTTCCCTGAAACTCCTTTGACATT TAAAAGTTGTCAAGACACCATCAGGTATTTCAAAATGAGATCAGCTCTGATTCATTTGGA TAAATCAAATGATTTATAAAGTTTATTTGATTGTGTTGGGGCTTTTGTTTCCATATTTCC CTGGATCTTATTTGATGGGTGTATATATGTGTGTGTGTTTAGTCAAGAGTCATTATGGAG TGGCTTGGATTTGGGTGAAAAGAAAAAAAACCTCTTTGGAAATTAATAATTTCTACATCA CTGTTTAAATCTTTTAACTCTTATTCCCAAGTTTTAACAGCTCCTTAGGACAGAGTTTAA AACAAAGTGTCATGGGAGTCCACATGAGGAGTGACTAACTCATTCTGGAAGACCTCCTAG AAGAAGTGACATTTGAGTTGGCCTTGAAGGATGAATTGTTCGCCAGATGGAGAAAGGGAT GGGTGTGGGGTGGCTTTGGCCGACCAAAGGCGTGACACGTGAATGGTGTGGCTTTGGCAG ACCAAAGGGGTGACACGTGAAAAGGCAGAGCTCTGAAAGCCCACATATTTCATTAACCGT GGGAAATTAGGTGCCTGGACTGTGAGAGATTACAATGTGAACGCTGTCCCTGGAACCGTG AAAGAGTGGTTTCAAATGGTGAGGAGCATGGTCAAGAGACTGGAAATGGATTTGGGACCA AATTGAGACGGGCCTGTGTCCTAAGGAATTTGTTCTTTACATAGAAGGCAGTGCTCACAT TTGTATTTTAGATTTCTGGGTGGAGAATCACCTGAAGAGGGCAGACGAGTTGTTGGAAGG TGTTGACCGTAATACAGATGAGAGATGAACTGTTGTAATGGAAATGGCAACCCAAGGAGA TTAGGAGCAAGATATTTAGGCAATAGAATTGATTTGCAGAAGGAGAAGGGATTTGAATTA ATTTTTATGGATTATATATGATCAATGTGAGCTTTAACCTTGTAACAGCCCCATGAAAGA AGTTAGTATTTTGTGACTGATTTTTTCGGGGGAAGAAATATTAATACATTTCTCAAATAA GGATACTGTAGTCCAAGAAGTTTGGGAAACAGTAGATTAAACAGAGTGAGATCATTTTTG CTCTATTTATATTATTTCTCATAACCTTTAATTTGGCAATATGTTTGGCGAATTCCCAAG AGAGCAATATAGAATGACAGAAATACATCTCAAAAACTATTTGTTAGTTGAAGCTTACTT TTTTATTTTAAAAAATTTCTTATAAGACTCATGTTGAGAGAGGTCTTATATCTTTGCATT ACAAACGGGAAACTGAGAATAAGATTGAGTATCTTGTCCAAGGATTGTGTACCTAGTAAG AATCCCTTTATATTTAAACCCATGCCTTTTATTTTTCATGATATTGTAGTTCTGTTGAAA TTGTTGGATTTAGGGTTTGAGCCTAGGAGACGAGACGAGTCAAGACTGACTTAGAGGCTT TAGTTTGAGTGACCATGGCTGCTGGCACTTTGAACCAGCAATAGGAAACTTGAATACCGA AGCAGTTTTGGTTTTGTTTTGTACATGTAGGAATGGAATGGATAATCATTTAAGCCTTGG ACTTGTTGGATTTAAGATACTTGGTGGAGATGCCTCGTAGGCAGTTGGAATATCAAAAAA TGAAAGGTATACTTTTGGACTTGACACAACTATAACTTTTTCTGTTATAAAATTGGCCAT TAAAGTTTGGATGTTCAATTTTATTATGACTTCATTTATAAGTTGATGTCTGAAACTGCC AAAGTAGGCAGTTTGAAAACTTGTTTTTTTCCTAAGTGCAAGTATTACTTCACACCCAAG TGTCATGTTTCATTTTACTTGTGTATGTTTTGTCAGAAAGCTGTCTGAAGAAGTCTTTAA AGGGAAAATATTTCTACTCATTTTCTTTTCAGAGAAGTATACTGTCTAGCTCTTACGGCA TATTTTAAGGATTTCTTGACATTAACAACTGTCCATGTGAATGAATTATTATATCTCAGT GGTATTCTCAAGAGTTAGTCACTTCTGCCATGAGGTCATGTGTATGCTTTAATTTTTTTT TTTTTTTTTTTTTTTTGAGATGGAATCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCA CAATCTCAGCTCACTGTAACCTCTTCCTCTTGGGGTCAAGCAGCTCTCCTGCCCCAGCCT CCCAAGTAGCTGGGATTACAGGTGCCCATCACCATGCCTGGGTAATTTTTGTATTTTTAG TAGAGATGGCGTTTCACCATATTGGCCAGTCTGGTCTTGAACTCCTGACCTCAAGTGATC TGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGAGTGAGCCACTGTTCCCAGCCAA AATTCTCTGGTCTAACTGTGTGTCAACAGCTTTGGCTTGATGTGCTTAAAGGTTTCTACT TTAATATTCTTAAATATTGATTGATTGAAGCTGATATTCCTTAATTTTCTACCATTCCAT TATCATTATTGTCATTCAGGTTACTAGAGAACTAGCTATTAGATTCAGAGCCATTGCCCA CACCTTAAATGATCAATAGTATCCTGGAGAAGTGATGCAGACACCTGAATACTTTGGTAG GCATGAAGTAAATGTCAAGCAATGTGAATAAAATAGTTAATGTAAATTCATAAGTCATTT TTGCCAGGTGGCAATTGAACCTGGTTTTATAGATTATTTACTCCTTGTAGGATGATGGCT CAAAAGGCATTCGGGTGGTGGTGGTTGTTCGGGAAAGTCAGATATTTAGCTTATTTACAG AATGACAAGCAGACATATTTGGCTGGAATGCAGAATTCATGGAATTGTATATTTGGACGT TGGCTTAAAATTAAGTGGCTTGGGGCCAAATTGTGGAGGACTTTGTGATATCTGATTTCT TAAGAAAATACTATCTCCAGGTCTCTCATCAATACCAGTCTGGCTGTCACTTTTCTGTGG ACTAGTTTATCTTGTAGGCCAATGAAACTTGAGCTATAGAATGGCACACACATGCATCCA ACAAAATGGGACCAGGGCCTCTTCCCCTCTCTCTAAATTTTTATTTCTCTACCACCATTT GCTGGGATTTTTTTTTTTTTTTGGATATTTTGATAGTGAGCTTTAGGTAAGTTTAAAGGA AAAGATGAAGTTAGTTGAATTTCCCTTAAAATACCAGCAGAAATAAAGCAAGGAGACAGC AGCTGTGAAAACATACACCAAACATCTCAGTTATGGTCTTATCATGCTAGCTTCAGTGCA GGCTCACAGTGTGTGCTTCTGTTTCCATGGTTACCTGCTAGGCAGCAGAATCCCCCAGGT TGGTATGCTATAGAGTCAGGATTTTTCATGGAAAGGAAATTCAAGTCTTTTCAGAGTGAA GTTAATAGTTTTCTTTTCTTTTTTTTTTTTTTTAAAGCAGATGGGTTATACATGTTTTAA AAATAAAAATGGTTACTGCAGGTTTGATTTCCAAACTGTAAGTGAAGCCAGACTTTAAGG CAGTGTTTTAATGGTTTGGAAATTCTAGTTTTCAAATGGTTTCTCCTAGATGGTTCCCGT GACAACACAACTTAAGCAGGTATCGAGTATCATCTTTGCTGTGAAATATTCATGCCACAA AAATTCCTTTCATTTTTAATTCCACGCTAATGAACTAAGGCAGAAGAAGTTAGCTTATTC AAGGACAAATGGACAAATATTTCAAAATCATTGTTGAGCTTAATAAAATTGCAATTCTAA GTGAGCTTTTAAAAAATTGAATGATGATATCATACTTTATTATATTCTTAAATTGATGTT TTGTTCCCTTGAAACAAGTATTATTTCAATTGCTACCTGGAAAAAATAGTATTGTTTTAT GATAGAAAAATTTGAATTTCATAGTTGTAGCAGAAGATTGCTGTTTTAATAATGCCTGTT TTGTAGTGTAGTTAAAAAGCTCTCTCAGTGTTTTGGCATATATCTTTCCCCACTCAATTT TTCTTCCAAAGAAAAATTTTATTGTTAAGCTAATACTTGATAAAGCCATTCATTTGTTAA AAGATATGATTTTTTTTAAAAAAATAGCTTTCATGCATGCATTTTAAAACTTTGTTAAAA AATTAGAATGAGGTGCCATTTAAAGAATAAGCTTCTAATTCATTAATAAAAATTCATTAA TATTTTTTAATTTTAAAAAGAATAATTTTTTCAAAAGTGACAATTATTCTTTATTTGTTG TTTAATATTTTATTTTATTAGCCATTGAAGAGGAAGCATAAAATCTTACATTCCATGATG AAACTTTTATGATTTGACATCTTTATCCTTATCTTGAGATTTGCTGATGAGACCCCCTTT ATCAAATTCAGATGTCTCTCTCTGATATTCAGTACAATATCTGCCTCTGGACCAGGGTTC AAGGAAAAGGATGGATACAGGAGGTCATTGTGAAGATACTGGGTAATAGAGAACATCTGG AGGTGATCAGAGATAGCCTTATAGGAACTGAACCATAGAAAGGAAGTTCATTACAGCAAA TGGATGAAGTTGATGGTCCAGAAGAAATGAGAAAGATTGACCCATGTTGAGAGTTCTTAT AAGAGTGTTTTTATTTGGGCTACTTCTGCAGATTCAGTCAGGCCTTAAATTAGATTTTCT ATCTCCTGTTATGACCCTGTTCTGCTACATTCACATTCTTGATTAAATGTTATAGTAAAT AACTTTATTTCCTTTAACCACATGATGACTCTAATCTTCTAAAGACTTTCCATCACAAAA CTTCAACTTTTAACCACAGGTTATGGCTGTCCATAAAGTATTTTTCAGTAATTTTCAGTC TTTCACATCATAAAGTCCTGGCTTAGGGGATTGGGCTCTGGAACTTGACTAACTGGGTTG AATGCTGGTTCCGCCACTTATTGGCTCTGTGACATTGGACAAGTTAATAACTTGTCACAG TATCTTCAACTGTGAGATGGGAATGATAATAATAATCCCTCACAGGATTATGCAGGAATT AATATATCAGAAATATCTAGTGTTAGTTTTCTATTGCTCTAACAACTGACCACAAACTTA GCTGGCTTAATACAGACACAAATTTATTATCCTATATTTTTGTAGGTCAGAATTCCAGCA GTCATATCACTGGGCTAAAGTCAACGTGAAAGCAGAACCATGTTCCCTTCTGGAGACTGA GAATTTGTTTCCTTGCCTTTCCAGCTCTAAGAGCCCCCCACCGCCCCCCCCCCACATTTT TTTCTGATGGCTCCATTCCTCTGTTTTCAAAGCCTTTTCTTCTGTAGTCACATCTCTCTC TGCTTCTTCTGCCTCCCTCTTCCACCTTTAAGGAGCCTTATGATTACATTAGGGCCACAG ATAACAATTAGATAACTTTTTATTTTGAGATCAGCTAACTTTTTATTTTGAGATCAGCTG ATTAGCAACCTTAATTACCTTTTGCCGTGTAGCCTAACACAGGATTTAAGGGTTAGGATG TGGAGATCTTTGGGGGATCATTGTTCTGTCTGATTTGTGTTTTTACCTCATGCTATCCTA TTATAGGGTAGATATTTGTATATTTCTGCAATTCTAATATTCTATCTATTTTGGAGCATA TATATTACCACAGGCAGATGAGAGAGGTTGAAGGAAGGGAGAAGTAGGAAGAATTATGTC CTGGTATTATTTTTTGCAGCCACAAAGAAGTAATTTATTTGTCATATTTTTGTAGCAATC CAAATTGGCCTTCCCATTTGGTTAGTGCCTCTGAAGTTTGCTAAAAGCAGTTATAACGAT GTGGACAGAATTTAATCTACTTAGCTTTGAGACATCTTTTTCCTACTGAAACTTTATTTT GCTTACATCTATAAAGTATGGCCTAACTACATCAAATATTACAATTTAGGGTGAGCAAAG ACTTAAAACAATGTATTAATATTTGTGAAGTGCCTCAGCATTTACAAATGTTTTCATAAA AATTATTTTATGTAGCCTGTCAGCATTTGGAGAACTAAAGCAGCTCAGCTCTTTCAGACA ACAAGGTGTCTCTGAATATTTGCTCCCTCATTGCTTCTGCCAAAGAGGACAGGGGTAAGA AAAACACCTACCTTCTTCCTTAATTAAAATTTGGCAGTGGTATGATTGGTAAGAAGGGGG AAAATGATTGAGGAGGTGAGTTCTCAGTTTCATAGCTGAGCAAACTAAGGTGAGAAACAC TAAGGCTGCTCATTGCTATGGCTGAGTTTCTATCCCAGACTGGTTACCTTTGTCCTTGGT GTGAATCAGTTTGCAGGAGTAGGCTAGGAGAGGCATTCTTTCCTTTTCCTAAAGCAGAGC ATGAATACAGGTATTCATTAAGCCATTGTTTCCTAGCTGGGTGTTCATCTACTGGCATTG TCAATGATTGCATATAACAAAAAGGGAATGGAGAGAAAAATCTGTTCTGAGTTCACAAAA CTCACTGAAGAAAAAATGTAAAGTCAGCTGATATGTCAACAGCAGGGAAATAATTCATTG TCTCTTAGAAAAGCGAATGCCAATAACAATAGCCATGATTCTGGCAACAGAGTAGTACTT CAGAGGGTCACTTTCAGCTCTTGGCTTTCTCCTTTCCCTCCATTTCCAAAGGACATTCTC CCCAGCAACAGAAACCAAGTGATTTATCATGGCTCATGTCAGCTGCTGAGGTTCACGGGA CCACACAGAGTGGTTGGTCAGCCAGGTCTGTCTTTCCATGGCTGTTATTACAAAGGAAGT ATTCTTTTATAAAAAGAGAAATATAAAGTGATATATTTGTTTGTTATTAAAGCCTTTTTG GATGCCTTAGAGAAGATTAGCTTCAGCTCCAGGGTGCCAGAGTAAACTTGCATTTGATAA AGCCATGGTCATTTCTACTGCTGTCTTTATTGCACCCAAATCTTACAAGGTAAAAGATGT GAAGAAGACAGCCTTTCCTTAATTGTCCATTTTGATTATATCTTTGTATTTAAAAAAATA CAGAAATGAACTTTAAGACCAACTTAAATAAATAAGCAAATAAATGATGTAAGAGATAAG TATGCAGAAATAGTTATTCATTTCTTAGGGGTTTATACATTTTATTTATACCTATTATTA TTTTTGATTGAAAAATTATCGTATACATTTATGGGGTACAATGTGATGATGTTTTGATAT ATGTATATGATGTGGAATGATTAAATCAAACTAACATGTCTATCACTTCATTTACCTATC ATTTTTTATGGTGAGACATTTGAAATTTACTCTTTCAGTTATTTTAAAATATACATTATG GAGTATATACCTTAGATAACATAAACCTTTATATGCTCTTTCTAAAAATGGCTATTTGAA ACCCTGTGTATAGCCTTTTGTCTGTATCTGTCAACTTAGTTTTTAAATATAAAACCAATA ATAGTTGTTAGCTCTCTTGCTTTCATCAGGGATTGGCAAACCACATTTCACAGGCCAAAT CTGGCCAGCTGCCTGTGTTTGTAAATAAAAAGTTTTATTGGAATACAGCCTCATCCATCA TTTACATATGGTCTTTGTATGCTTTCGTGTTACGGAGGCAGAGTTGACTAGCTAAAGCCA AGTCCAAATGGCCTACAAAGCCTAAAATATTTACTATCTGGCCCTTGCAGAAAAAACTTT GACAGCTGCCAGACAGGTAAGTTACATTATATCATACTAGGTGATGTGGGTTCAAAAATT ATTTAAGACTTAGTCTTTAATAGTTTATAACGTAGCTGGATAAAAGACATACCAAAGTTT AAGTGATAATACAAGTCAGTTTTAAATTTATGTTTTCATTGTCTCAAATCGAGTGACTTT TGAGAGTGTCCTATATGCCAGGCAGTGTTCTAGGGACTGGGATGTAGATGTAAAGAACAC AGAATTTTTGCCTTCATGGAGCTTATAACCTGGTGGATCAGGCAGATAATAAAGAAAGAA TATATAGTATAATGCTATACTATACATTCTTGATACATTGAGATTTAGCCCAGGTCACAT TAATAGTCTTGTCTGCCTTTAGCAATAAATTGGTTACTTTTCCTAAATATCTTTTTCTCC AGTAAGATTCATATGAAAAAGTGGTGGGGGGTGGGGAGAATGAAAATACCTCAAACCAGT CATTGTTTCTCTAAGTTTGTACACGTGGTTCAGAATTCGATTTTTATCTTGACGTAGGGT GGAAAATATTATAAACCTGTTCTGGTATAGTAGAAGAATATTTGATTGGGAAACAGGAAA CCTGTATCTTAGCCCTAGTTTAGTCTCTTCGGGCTGAGTGGGCTTGTAAAGATTCTTAAC TTCTCTGGAGCATGTAGGGTATTGTACTCGGTCAGTATTTCTCAAACTCGAATGTTCGTC AGAATCACTTGGAGAGTTTCACATTTTTGAGCCCTACCCCCTGAGACTCTAACTAAGTGG GGCCTGAGAAATTTCATTTCCAGTGAGTTCCCAGGTGAGGCAGCTGCTGCTGCTGTTTTG GGAACCTGCTTAGAGAAGGATTGCACTCCATCATTGTGGAGGTCCTTCCAGTTTCTCCAT TATTTTTAAACTCCCTGGAGAAGCTTTACAGCTCTTTGAGCTTGCCTAGGAAGATTCCAC TAAATAATGGTTTGGTTAAGTTGTCTACTTAATACTCAGGGCTATTTGCTGAGGAAGAGA TTTCAAAGACATAAGAGTTTTTAAACACTTGCTTATGGTCACATGGATTGATATTCATTT AATTGATATTATGTGGTTTCTTTGGGAAAATTAATGTTTGCTAATTCTAAGGGCAGAGAC TATTGTTCATGATTTCTTCTTTGTATCCTGAGTCCATGGTATGCGTTAGATGCTCAATAC TGATCTGTTTAATTGATCTAAACTTAGAGAAGCACAGAATACTTCTGAAGGTCATCTTCC TGAGTTCCTGTTGGGTTTCTGTTATGCTCTATTTAGAATTAAGAATCATGAACTCTACTG GCTGTCAAAACTATACGCATTATTGTATTTTTGCAATGTGTATTGGTATTATTTCTATAG AAATTCCAGTAAGAACTTCATATTGATATTCAGTCTGTCTCCTCCTTTGAGTCTGAATAT ACAGCAAAATAAGCAGAAACAAGACAAACAGTATAATAAATAAAAGTTATCCACATTTTC TGTTACATATAATGTATCCACTTAATTTCGTATAATTCAGATGTTTTTGTTCAAATGTGA CTTTTACAGAGCATCTCTTAAAACTGTAATGTTATTAAAATAGGTTTAAAAAGTAGATAC TCATTTCAACCTGTTTCTCAAATGCCCACTGTGGATCTACAAAGATGCATAAGATAAAAT TTCTGCCATTAAGTGCCCTCCAGACCCTTAGTTGAATAAATCAAGGATTGAAGAAATGTC CAAGGAGCCAGGCACCCAGTGCTTCAAAGTTGGGATTTTTATGACTTTTTAAAATGTTGG CTCAAGTTAAAAATAATCAAAAATGAAAACAGTGTGGATCAACAAAACCTAGAGTTAGTT ACCAGCTGAATTCTAACATCAAGCCTTCAGTTTATAAGTTTTGAAACATGGATGCACAGA CATAATATTTGGGGATGTTTCATATGATCTGGAGTGAGAACAAATCTAAGTGCAGAGATT AGAAAAAGTTGCTTAGAGGACCTGGTGTTTGACATGGACTTTGAAGGATAAATAAAGACT CTAGAGCAAAATCTAGAGCAGTGTGAGGATAATGAGTCCTAGCAGAAACAGACCATGAGA AACTTCTAAGGCAAGTAGATGGAGTCAATGTTCAGGGCATTGTGAATAGTTTATTGCTCA CAGCAGGAGTAGAAAAATGGTAGCGAGTGAGAGAGAAGACTGTTAAGTGTAGTTGGGATT CTACTGTGTGGACCCATGATGGCCAGTTGAAAGTTTTATACTCAGTGTGTTAGGCAACTT CAATCACCAGCCATAGACAAGCATTATTAATCTGGATTATATTTATACCCTATTTCATCA AATCTAAAATGCCATTGATTGTTAGAAACATATAACCACTAAGGAAGAAAAAAAATGCCA CTGTTAAACTATGACAGAATGCTGTGTTGTCATTTGGAATTATTTTAAGTTCATAAGAAC TCTAAGATTTGTTTTGACACAAGAAATAACGAACCTTTGTGTCCCAGTTTGTGCTTGCAT ATAGATCTATGTTATGACCGCTACCAGACCACTAGCTATTGCAGCTATCAGTTTGAAGAT GCATCACCACTTCATAGAAGTTGAAAGGTGCATCCTACAGTCAATAAAATATGATAGGTG AAAAAGTCTACATGTTGGATATTATACATAATGGATTGAGTGGAAGATTTTTTAAACAAA ATGCCTCCCATCTAGGTCATAATTACCATTATAATCCAGCTATTACCATTTTCAAGTGAA AAGCTTGTTAATTGTGACTTAATGTTCCAGAAATCGGAAACCTGCTTTTTAATTGGAAGC AGTCTTTACTCTCTTGAAGCCACGAATATTTTCTTACCTGAAGGGTGCTCATTGAAAACA GCTGATTCCTATTTCGTGTTTGTGTTCTTCCTTGGGAAAGTCTTTTGCATCCCAAGCTTT GTTTTTCTTTTTCTCTTTCTCTGTTAAAAAATGTTAAGATTTTATGAAACGGAAGAACAG CCCTAGGGAATAAACTCTTAATCACAGAGCTGATTGAGTGGGTTTGAAACAGAAGATGCA CACACCCAAATCAATAGCCATAGAAGGATAGCAGTTCTGCAAGTCTCCAGTAACTATTCT TAATTCAGAAAAGCCAGGAAAGGTCACAGGCTCCAAATAAATAAGGTTGTTTTTCTTGCT CCTTTAGTGTTTTGTTTTTAAATCACCCATGCCTGTAACTTAACTGAAACGTTCCTTTTT ATTTCTATACTACTAAAGTGATTCTAATATAAATGGTACAGTTGTTGAAACACTGATCAC TGCCATTTCTTAAGGTTTTGATGTGGTGTTTCTGACTGGTGTCAGCCTACCATGCTATCC TTTTTGAGATGTTACTAATAAATATTTGTAATAAAATATAAATGTTAAAAACTATCAGCT GTTAATTTCCTTAAAACCTAATGAAGTCCTTTATTAATAATACCTGGGATATGTTTTGTA TTTAGGAAGTAACGTGCCCAGTGGGAACTATTTCATTTGTTCTCTCTGTGTGTTAGGGAT GTCTAACTTTATCTGTTGAGATGCAAAATATTTCACTGTTAAGCAGATAATATTACTGGA GAAGAATAATTTAACATCCAGGAAATGTTATAGCCCAAAATATAACTGTTTCTTACTGCT AGTCAAAATACATATTCTGCTTTTATATTTTAATTTTTTCTTTATTGAACCATTAAAAAC TTCAAATTTTGTTTAGGAGAGACAAACTTTAATTTAACTTCTTTGTATTTTTAAAGTGCC TGAAGCATATATCCATTCACATGTAGGTTTGGAACCAAAAACCACAGGCTCAATATTTTT AGGGAATCTAATGCATTTGGAAATTGAGACTGTACATATAACATACCTATAGGGTGCATT TATTTTTTTCCAGAAAACCAAGTTTAATAATGTGTTAAGATGAAAACAAGCCTCCCTTTC TGTTATAACCTTCTCTACATTATACCTCACTATGATTTCACATGAGCTATTGAACTTCTA CAGTTTTTCTTATTTTTAGACATAAAATTGGATGTTGTATGCATTTTTAAAATATCTCTT CAGCTAAGGAGAGAATGTGGAAAAAACAAAGAGCAAACCCACTTTGCTATAATTATATTG CTGAATCTAAAGGATTTTTCACTGGCACCGCAAAGTGTAAAAGAGCCTCACAGTGTGACA TTTGTGCTGTTGTGGAGTTGACCTAAGTATATAAATCTAGGTTTTTGTCATCAGCGCGTA TTGATGGCATTTTAAATATATTGGCATGCAGTTCTCTGATATTAGGCATGCCCAGGGATA GAGTTTGAGTATCTGCTTGCAAAACGTCTCAGTAGAAGGATCTAATTCTCTGGCACAATT GCAAGATTTGGGCCTTCCTGAACAATCCTACTGTCTGTCTGGGGCTGATTCTTCGGAATG CCATCAGAACCTGGGTTAGCAGCAGTTGAACCAGGGCTCAATAATGGGTGAAGAGAGAAA GAACAATTTTCTTTTAGCATCTTTATCCTACTTGGCTGCTAGGCTGCTGTCTTTCTTCTC ATTTCTCTTCTTCCTGAATCTTCTTCTGATCCCATCTCCTTAGTTGAGTATCTTAGAGGC ACCGTTGATTCTAGAAATAGTTTTGATTATTTTCAAGAGCACATCTGCCCTGAATGCTAA AGGACATTTCAAAACCATAGTGGTGGGCAATGTTTTGTTACTTTGGGTATACAGCATTTA CTTTACCATGCACTTTCATTCGTGGCTGCAAAGAACAGAAAACCCAACCAGTAGTAGCTT CCAAGAGCAAAGGTGAATTTTCCCACTTAGCACAAAAGGTCTGGAGGTCAGCAGTGCAGG CTGGTTCCATTGACTGATGATGCAGGTGACCAGGGACCGAGGTGCCTGCTCTCTAGAGAG CTGTGCTGGCTTTCTTTATGCTTCCCATAAAGAAAATGTGGTCACAACTTTGTAGCTGCA TCTGAGTAATCAGGAAAAAGTGGGGCGATTGAAGGGCTGCAGGGTGTTCCACTCTTCCTT CCTCTGCAAATGGGTATTTACACTGCCTCTGCTGGGCTCCCCAAAGCCTAGTGTCTCAAA GTCAACTTAATATTTTTCTATTTGATTTTACGTTGTTGTTGTTTTTGTTGTTGTTGTTGT TGAGATAGGGCATCCCTTTGTCACCCAGGCTGGAGTGCAGTGGCATGATCATGATCATAG TTTTCTGCAGACCCAATTTACCAGGCTTAAGCGGTTCCCCCACCTCAGCCTCCTGAGCAA TTGGGACCCCAGGCACACACCATCAGGCCTGGCTGATTTTTTATTTTTGTTAGAGACAGA GTCTCGCTATGTTGTCCAGGCTTGTCTCAAACCTCCAGGGCTCAAGTGATCCTCCTGCCT TGGTCTCCCAAAGTGCTGGGATTACAGGTATAAGCCACCACGCCTGGTCAGTTTACCTTT CTTATGTAGACCTTTGATCCATCTGGAATATGTTTTTGTATATGATGAGAGGGATCCAAT TTTTTTCCACAAGATGAGTCAGTTTTCCCAGCATCAGTTTCTAGATAATCTGTCCTTTCT CACAGGCTTATGATGCCACTTCTCTGCATCGGCCACACCTGCTTTCTTTATGATGCCACT TGTTAGCTAAGTTGGAAAACACACACACAGACACACACACACACACAGTCTCTTTTCTCT CTTTCTTTTTCTTCATCCCTCCTTTATATTTTTCTGGAATTTCTATTCTTTTCCATTTTT CTCTTACACTTTGTAATATACCTTGATATATGCTGGACAAAGGCCCTTTTTGCCTTGCCT TGCCATTTTTCCCTATTCCGTACTATATCATTTGTCCTGTTTCATTTTTCTTCCCCCCCT TTACTTTTCTTCTCTTTTTCTTCTTAAAATTGACAGTAGATGATATCTCTGCATACTCAC CATATGATAGGACTTAATTTTTGTGTTTCTCTTTCATTGACCACCAACTGTAAAGCAAAT TTTGAGGTATTAGGTGTATAAAAAGGCTACATTCAGCAATAACAGCCTAAAAACAGCATA CTGTGTGTTTCTAAAAACTGTATGTTTTTGGCCACTACAGAAATTTTGGGTTTGTTTTGT TTTGCTTTGGTTTTGACTGCCAGATGGAGCAAAGTGTTCATGTACAGCTCAAACATAGCT CTGTATAATGTTGCCTTTTTTTACTCTTGTCTCCTTACAGTCATTATCTGACTAAAAGTA ATTAGTGTGTTGGAAATTTAGAGTGAATAACTTTGAGAGGAAGCACTTATTTTCTTTTAT TGCAAGTAAAAGATGTTTTTTGATTCAGTTGAATAGTACTTGAAAGACTGAACGAATGTA GCAAATTCTGTCAGCAAACTGGATAATCCAAAAGTTGAAAATGTGGGGGTCTGCAAAAAT CAGTTACAGAAGATTAAAGTACCTTTGGTAGCACATTATTAAGAAAATCCACAGCTGTTT TAAAGTGGGTGTTTCCTCATGGAGAAAAGTCTAAAGTCTCTTGCAGTTACATTCTGATTT CTTCGTAGCTTGCCAAAGGTTGGCAACCTTTGCTCAGTACATGCCTCACACGGCAGGGAG CAGGAGTGTCTCATCATTTCTGGGGTGGGTGGTCTCCTTGGGGGAGCCCAGGGATGCCTT ATGCATGGCTGAGAAATTTTCTTTCTGTGGCCCTCTGTACTGTATGGGCTTTAGGGACAA ACTTGTGAGGGGGGGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTAAAACACTCTTCTT GAGCTCTGACTGCAAGAAGAAATGGTTTGAGAAGACAGAGGAAGGCTGAGAAAGGACTTT GAATGTGAAAATGCTATTCTTGTAGCATCCTTAATGCCATTGGTCCTTAGCTTTATAGAT CAAGATTGCGAGTGAGCCCCTTATAGGTCTGGGGTTTATTGTTGCTAATACCAGATGAGT TACAGTATGTATTGCAGTCCTTGTATTTTAAGTTACATCTGGTTTCTCTTAAAGTTCCTT AGTAAACCAAAACTGTTGGTGAGTGGAAGCCTGATGCTGAAAATTTTGAAAAGCAACTGT GTCAGATCACAGGATTTTTCTTTGTTTTTTGTTTTCATAGAGTTGTTTTGGGCTTGGTGA CTGTTTCATTTAAATCAAGTATAAATGCACAGAGGTAAACAGACACTCCTATTTAGTCTT AAGAACTTGGTTTGATTTGGAATTTTAACTGCCAGGGCCCACTGTTTAGTGTCTAGCCTG CTTTCTATTTCCTGCGCTATTGTTTTGCTTTTGGTCACCTTAGGGGAAAGGCTACAGCTT CCATGGTCCCAAAGTCAGTGGCGCTGTCAGATTATAAACTGAGAAGAGCTGATTCCTTGG TGGACAACCAGAGTTCTTCATGTGATTTTAGTTTACATTTAGTTGGATTTCACATTACAG TACATTTGGTGAATTATTTCCTGAATGAGACTGAGAAATCACTGGGCTCTGGCAACTCTG TACTGCTTCCTCTGCTTTAGGGATTTTCTGTCTGAAATCTTCAGAAAAAGTTGCAATAGA GTTCATGAAAACCCTCAGTTCTAAATGGACACATGAAGAAACACCTTAGGTTTGAAAGGG TGTTTTAAAATTACATTCCTGTCTTGTATTTTTTTTTCTCCTTTTTATTTTTTTTTTCTT TTTGGCCTAAGTTTCAATGACATTCTGGAAGATGAATTTCAGTTGGGTTTTGGGAAACTA TTTCCAGCAGCGGTTGAGTCTGGATTTGATTCCACAGAGTTACAGCCGAGGCTTCTCTGC ATTGGCCACACCTGCTTTCTTGAGCAACCTGAGAGACACTGCCTGTGGACATTTTCCACT ACTTAGTGATTAGTCACCTCACAGTTCTGCTGTTTTTGCCGTGAGATAATTTCACTTTCT CCTTCTGCTCCTGCGTGTTCTATGTCTGTTTTCACCCATCTTTGCTTTTCCCATTTTCCT CTGGATTTATTTATTCTGTCCCTTACATTTCTTTATACATTTGCCTCTTCTTATCCTGGG AACCTCACACCTCTGCTTGTTCCATTTTCACTTGTTTCTGGATGTGTTGTATCTATTCCT TTGAAAAACGTTGCTCTTTTGTAACATGACCTGTCCCAGCATCATCAAGATAGAGACTTT TAAAAAATACTCCCTTTCGTATCTTAGAAGGCAATAGATCTTCTTTCCCAGCCAACCAGC TGGAAAGGCTTTTTTTTGCTTTTCCGTTTTTTGCATTTCCACGTAGACTGCGTTGCTCCT TGCTAGAGAAACCACAAGCATTCCTGTGTGAAATGAAACTCGCTGTTTTGTGATTTTGTG TGTGGGGGTGGAGAGGGGCATGGTAATATTTAGAGTCCCTGGCCTTTGCCTCCCAAAGGT TTGTCATTAACATTTTGTTGATTTTTAAGCTTGCTCTTATATTTAGGACCAGTTTACTGA GTTTACCTCCCATTCCCTTTCTAGCAGGACACCCAAGAGTCCTGTTTGCTCATTTCCTCT TGTCCTGGTCCCACCCTAAGGGTTTTCCATGGGCTCGCACTTCTCAAGGAGTTCTTGGGA TCCAGGACCCTTTAGCAACTACTAGCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTG CCAGAGTCTTCTCCTTAGCAACTGTAATGGCATATTAAGTTACCAGTTAATTCCTTTGTG AGGAAGCGTAGCAGTTTAATATCGAACAAAGGCATGTTTGAGCAAATATTGACAATTGAA CACTTTAGCAACATTAAGATGCCTTTTATAATGGATCTGTCTTACAAAGAAAAGCGATAA CTTTCTAGTCTCTTATGCTGTCCAAAACTCAGGGACTTCGTAGATTTAGATAACATGATT TCCTTGGTAGTTGGATTTCAGCAATATCATAGACTTTGATAGTGAAGCATGCTTGTATGC TATTTTCAAATAATTTTCATTGGTGCTAACATTTTTAAAAATTCAATTATTGTCTCACTG CTTTAATTTCTTAGTTACTCTAATAACAAAGCCCTTTTATTGTGCAGAGAAGTAACCGTA TGTAATTTATAATACGGGATGCTGAACAGGACTTATCGTGTAACCCGCTACAAGACTTTA GAATATACAAGGACTGTATATAAAATAATGAGACCAAGTCTGTGGCTCAGGCATGAAATC AGCCACCTTGTTGAATGTTAAACTACTTTTATATAATGTTCTGTGGATTTGTATTTGTTC ATGAGTATGTGAACATTTCTCCTCTATGAAATAAAGCTGTCAATGAGTTCTATGAAATCG TAACACATTTTCTATAGGACGAGTATTTGACGTTATGGTTAAATATAGTACCAATTTATC TACCCAACTATTATCATGTTTCTATGTTTCTACTGGAAAATGCACTCCTAATTGAGATGT CAGAGGTGAGAACTAAAGCCTCTGTGAGACTAGCATTTAAGAATGCAGAAGTAAATATCA GTGAGTCCATGCCAGAGTGGAGCTTATCAGTAAGTGATGTTATGGAGAGTATATATTCAG AGTCTCTGACTAAGGTTTCAGTTCCTTTAAGAGATTGAGTCCGTAAAAAGGGACAGGAAG GGCACAGGTCTTTTAATGCTGTACACCTATGTAATTTCACAAGAGCCAGGACCCCCCATC CAGGTCAGCCACTCTCAAGATATTCAAGACATAACTTCCTTCAGTGATTATTTGTATGTT TAGGTTGTTCTTGGGTAAACTGTGTTAGAACCAGAGATGCCATAAATATCAATGCAGTCT GTCCTTAAGCCTGTGGCTGCCAACTCAGATCAGCTGTGTACAGCTGACCTTTACATCAAA GGCTTCTCTTTTTGCTGCCACAGCAAAAGGTTTGAAGTTCTTGGCAGTCAGCAACACTGT GAAGAACACAAGGGGAAGATGCATTTCCTATCTCAGAAACAACCCATAGGAAGCAACCTT AGCAGTGGTGCTTGGTTTCCTAAGCCATTCTGCATAAGACATAACATACTGACACTTAAC ACATTTGCAGTATTTTTCCTTCTACTATCTTAAAAAAAAATATATGTAGTTTTAAAGTCA TCCTATGAATGATTAGGCTTCTGTGAGCCAAACCTAGGTCAGTAGCCGTCATTAAAAATT TTTTTTGGTTGGAAAAATATGTTGTATATTTCACATAACCAGTTCATATAAACACTTACA GAATATAATCCATTCATAAGTTTGCGGTTCCCAAGTGTGTGTTTAGCATGTGCCATATAT ACTTATAGATTTGACATTATATAGGAGCCCCTCACTATAAGTGCCTAAAGGTTGCTAGAT GATTACTAATGTATTCTTCCCCTACCAAATTGACAATTCTCTGCTACTGAATAAAAAATG GAACTTGTGATGTATCCTAGAACAGGCTATTAAATCACTGCCATGAGTATGACATTCACT AAGAAAGGAATTCCTGGCACATAGTTCATCTAGTTTTTCTCCTCTTCCCTATAAGGTCTG TGACAAAAAGGCAGTTCACTGTTCTTCTTGTCCCTGCCTGGTTACAAGGTTAGTTCTAAT AACCAAACTGTGGGTCTAGATAGTAATTCTATTTCAACCCTGTAAATAATTACCCAAAGC TGCCAAGCTTAAGAAATGTTTTATCAGACATTTCTTCTCATCATCGGTAAGTCTAAGATA ATGAAACAAATGGCACTAACTTTTTTTATTTTTTACTTGTGAAACATTTCTGTTTTGGGG AATAAAAGAGCAAGAGATTTTTAAAGCTCTGTTAAGTTCTGTAAAGTCTGATCAGAAAAT GGAATTAAAATTAATAAAAACTGAGCTTTTGTTCTAATAAGATTTTTTTTAAGCTGGCCA CTTGCTTAAGTCCAATTTAGCTTCCCAAGGACAGTATCTTTGATCATTAAAATATTTATT TATTTATTTATTTATTTATTTATTTATTTATTTATTTTGAGATGGAGTCTTGCTTTGTCA CTCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCATTGCAATGTCTGTCTCCCGGGTTCA AGTGATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGTGTGCCACCACACC CAGCTAATTTTTGTATTTTTAGTAGGGACGGGGTTTTGTCATGTTGGCCAGGCTGGTCTC GAACTCCTGACCTCAGATGATCTGACCACCTCAGCCTCCCAAAGTGCTGCAATTACAGGA GTGAGCAACCACACCTGGCCTGATCATTAAAATATTTAAGAGAGTGGCAATATAAGCAAA AATGATTCAATATAAACAAATACAAATTTCAATATAAACAAAAAGATTTATGAAACCTAA AATATTTGAAACTTTTCTAGAGAGAGAACACTAGTCTAAATATCTAGGAAGCAGGCATTT AAGTCCTTGTGCTGGCATATGAAATGGGTTAATTCCTTGATACAAACAGCTCTGGGTATT TATTGTATGTATTTGTATAGTGGCATAAAACATTCTTTACTAAGTTACAAGTCAAAACAG TAAAGGAATGAAAATGACTAAATTGTTCATTTGTTAATACAATATTTCCTGTTTACTCTT TTTCTATGGTGTAAAAGAAACTGAACATTGACTTTCTGTTTTGTAAAACCTAAAAATATA ATTAAGAAGAAGAGAGCAGGCCTGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGG GAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTG AAACCCCGTCTCTACTAAAAACACAAAAAATTAGCCGGGCTTGGTGGTGGGCGCCTGTCG TCCCAGCTACTCAGGAGGCTGAGGCAGGGGAATGGCGTGGACCTGGGAGGCGGAGCTTGC AGTGAGCCGAGATCGCGCTACCACACTCCAGCCTGGGCAGCAGAGTGAGACTCGTCTCAA AAGAAAAAGAAAAAAAAAAAAAAAAGAAGACAGCAAAGAAGTGAGAAAGGAGTTTTGGAA GGGGTTGTGATCATTTGCAATGTGACACGATGTTAGCTGCTTTTCATAAGCGCGTTTTAA GCAAATGTGTTCTTAGCTCTGTTTTTGGTTTTAATAGTAATTCCACTGTGAATTTGTATG TTGTGGAATGAGAGAATAGTGTTAAAAGGTGCCTGGTTGTTGCCAGATCTAAGAATGGGA ATGATTTTCTCAGGCAACTCTTATTCCATCAAGTGTGTTAAATTACTGTAAATTACAATC ATGCAGGAGATTGGTGGTCCCCAAATGACGTTTTCCACTATTTGCAGCTCCTTAGTGTAT CTATACCTAACAGTTTTGCATCTTGTTAAACCGCAGCATTCATATATTACGCCTCTTCCA CAGAGAAGCTCACATGTACATTCCAGGTGGAATCCCACCGTAATATATACATCACAACCA AACACCATAGAGTAGGTTTTCTGAATCATTTATTTAATTGGTATTTAATACAGAGGAATT TCTGTTTGCCAAAAAATGTTTTTTGTAATCTACTGTAAGCAGACTTAAATTGTCCTTGTT AATGGCTTTGAGAATTATTTTTTTTACCATTAAAGAATAATTTTCTGGGAAAATAAAAAA TGATGAGACTCATACAGACATAAATTGAACACGTGTTAAAGATTTTATGAATCTTATTAA TGGAGAACTAGGAAGATGTCATAACCATTCAAAGGAGAATCATAGATTTATATGGAATAA AGAAATGTGAGATGAATTTACAAATGGATCTGAAGCTGGCTTTTTCTAATGGGAGGAGGA ATGTAAATTGAACCTCCAAGGGACAGAATTTATTTGTATTGTCTATAGAAAAGACTTACT TTGCTTTGGTCTCATTTATCTAAAACAGAGCTATGAAATATTTCAGAGGCAGTAAAATGC CAGAATCAGAGGACCCCAAAGGGTGTTCTCTAGACAATGCATTGTTTTCCATTGGAAACA CCTAGTAATCCTTTTTGTTTATCACCCTGCCTGGCAAAATTTTTGTATATTTTTTTTTAA TAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGGACTCAAGTGATC TGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCCAGCCTA AGAGACCAAGAATTTATGAACAGAATGACAAGTTTGTGTGAAAGTACATGATGCTAAGAT ACAGATGAAGGCTACCCCACCTCTGTGCTAGCTGTCTACAAAAGGAGCCGAGTGCGGCTG GAAAGAAAGTTGCTTCCTTTCCAATTCGAAGAGGAGGTATACAAATCCTAGAGCTGGGGG CAGTGACAAGGTTTAAAATCGATGTGAGAGAAACACTAAGGAATGAGTCAGTGAAAGATT TTAAACTCCATCACACCCAACTCAGTTTCTCTTTAAAGGAAATGGCAGAGATGCCCATCA ATGTAGATTTTTAGAGATGGTTTATTGTGATTTCCCATTTATGTTAATTAGCTTTATCTG TCCCCTTTCATTTCTTTTGATAAAATCACTTAGAAAAATGTAGACGTAGTTATGTGTGTT AAATAATATAATTCAGTGTGACAAGGAGTTGCGTCCCTGAAGATGTGTTGTTGAGAATGG ATGACAAACAGTTCAGGTCAACCTTGAGTAAGTGTGAGGAAAAAATAAAAATAAATAAAT GAAGGATGTAATTGGGCTCCTCTCCTGGAGACTGAAAAGTAAGGACTGGCATGGAAATCT TTGATTTTTGGCAGTATATCATTATCTTTAGAGGTCTAGAAAAAGTGCCTACGTCATCCT TTCTATGAACACATTTCAGGAGCTGAGAAGTTCCTATCCATCATGAATAAAAGCAACCAC TTGCATGTGGCTTTTCTAGAAAAAAATTCTTATAAAACATTTTCATCAGGAAAGAACCAG GAGTCTAAAGTCAGATGAAAGAACGTCAGACTGTAGAAATCAGCTTTGTAGGTATGAGTC CAGGATCAGTTTGAGGTCAAACCCCTTTGCACATGTTTTTAACTTTGCACCGCCCTCGCT CTCAGTGCTGGCTCCTCCACTCATCTTTGTTGCTAATTCATGTTTGAGAGAGTCTGCACA AACTCCCCACCCAGGCTGGTATGGGCCTTAATGCAAGTTTGTGTGTCCAGGAGACTCACA AATCTGATCAATTTCAAGGGCAAGTAAGTGAAAGCTGGAGAATGTACAAACAGAAAATCG AAAGCTATGGAAACTTGAAGAGACAAAACGAAAATGTAAGAAATGCCACTAAAATGAGAA AATATGGTCAAACATTGAGAACTGATTTGCAGATAAGCTTTATGGGAATGTCTGTGAAAT ATTGGAGAGTGTAGGTGTCAGATTTGCTGAGTACAGCAACAAAAAATATCTAAAGCATAT AGTGGTAGTACCAAAATCAAGATTCATAAGGTTTTACATGATGTAGTATCTGGCCAAAAA TGTGGTCAGCGTTGTTTTTTGTTTGTTTGTTTGTTTGTTTCCACACTATGTGGTAAAAGG AAGAAGAACAGGTTATTAAGTGGCCAGCATTCATCTTTATAATCTGTGGTGTCTGTGGTC AGTCCTGCTGCAGGGAATATCCAGCCTGTATGCTTACACATGTGGACTGGTTTTCATGAT GGACCATTTCAGTGCCAGGTGGTGTACATGACATTAAGCTTCTGTACACACTCTTTTCAA AATTTTCTTTACATGAAAATTAACATCAGTTTTTATTATGAGATGGAAGTTAATAGTCAT TGACAAAACTTGAAAATGTACTTTAAAAACTTTAAAAAACAAAGAGTTCTCTCTCTCCAG ATCAACCTTACAAGTACATCACAGGATTTAAGCAATTTCATCGTAACACAAAGGAGGCCC AGTACATTCTTCAGTGCCAGAGCCAATCCACCTGTGTTGGTTAGACTCAATGAAACAGAA AGTTTATAGGTTCTAAATGTAAAATGGAGCCAGCCCTATTATGTTTGTTGTTTTAAGGCC CTGTGATATATTGTTTTTGTGAATGGGGGAAATATAGGAAAAAAAACACTGAGTTTTGAA TTATTAACATACTATGATTTGCTTCATAATTCTCAGATGTAGTTCTGTCAGATCCTCAAA ATGTGCACAAGATTGACCATCCCTTCCAGGAAGAAAAATAATATGCTTCCAATAATGAAT ACACTCTAAAAATATATGGTAGTTACTTTAAAAATATTGGAGATATTGGGAAAAATTATT AATATATATTTTTTCTTTTAAATGCTGTTAAGACACTAGTCACTGTAGCTGATAGCATGG GTTAGTCAACCTTCACAAGTGATTTTAAAACTGTGAGAGTATAGCCATAGCCCTGAGCTT TTCCCAAGACAGCATCCCAAAGAACAAGTTAAATGTGATTTAAATGGAAGAAGAAAATAT TTTGAGGTACAAGTGGACTCAATAAATTTAGGAATTACTATATTTGAAGGAAAAAAGAAA GCATAGTGGTTCCTACTAATGGATTGTGCCTCACTGACCATTAGAATTACATACACAGGA GAGATCCTTGAGGAGTTAAGTTCTGAGTACAGACTAGTGTTTATATTAAAGGACAAGATC ACATGCTGGTGATCTGTTAACCTTTGGATTGCTTTTTCTACAGTGTTCTTTCTTAAACTG TGGAGATCCCCATTGCACCACCCAGAAAAGAGAGAAGAGTAATGAATTTTGGACCTGGCA CGTTGAAATTAAAGAGCATGAAGAAAGTGAGAAGTTGTTTACTAGGCGTTTGAGACTAGC TGGGAGGCTTGGAATAGAGGCCTAAACTAGGAAACTGGAATTGGAAAGAATCACAATACT AGATAGTAAAGTTACACAAGTAGACGCCCTAGGCAAAAGGCCTGGAAGAGAATAAAGCCA AAGGGATCACTTCTAAGAGCAGAGGCAGAGAAGACAGGAAACTAACAAGGAATATCAAAT GAAGACTCACAGGCATGGAATTGCTATACATTTAGTGGTGTTTGGGGGCCCTCAGAAGGT ACAGGTACAGGTACAGTAACACATACTGATGTTTACTTACACTTAAAATGAAATAGGCAC TATTGTCAAAACCATTTAATGAGTGAGGAAACTGAGTTCACTTCAGTAGACCCAGGACTC ATACCTGTATTACTCTGAGAATAGCCAGTTGCCTACATTAGGCTTTTGAAAGCTTAATTA GACAAATGATGAAACAGAGAACTAGACATGACAGTGAATTGGCAGAAACACTGTTTCTTC AGAGGCCCATAATCAGCTTACATACCTAGAGACCCTAGACTGAGCCATAGAAGTGGAAAC AAATCTGATTTATATGACTGTGGAGAAAATCTTGTACTTGGAATGCTGTACCCTGTTCTC GACACATTATTGGCAGAAAGATACATATCAAGGAAAGGACCTGGAATTCACTTGTGGATG AAAAAGCAAAAGAAATAAATGTGTAAGGCAGTAAAAGTATATAGAAAGTGAAGGTGATAC TCATGTATGTGCTGACATAACAGAAGGAAAATGACCTGAGTAAGCATAAAACTGATGCCA GAGTCAGGAAGAGAAACATAGAGCCTGGAAATTGATCACTAATTTCCTTCTTTTTTTTTT TTTTTTTTTTGTTCTAGGCTTGACATTTTCCACTTTCTTTCTCCTAAAACAAGAAAGGGG ACAGGTTGTAGATTTTATGTCTTTAATTTTCTTTAATTCTTGCCTAACAGTGATAAAAAC ATAAGATCAGTGGGCTGAAATTTAGGGACACTGAGGGAATGAAAATAGAAAACTAAACCT GGATAAGTTCATCAGCATGTCTGGGAATAATCAACAGGTTATATGAGAAACAGGTTTTAG TTAAGTTACTAATCTGGAATAATCAAGGTGATAACTGTAAATTAGGAGAAAGTTTGAATC TAAGAGCTTGTATTAAAAGAAAGTTTTCTTTTCCTCTTTTGGGTTACATAACCAAATTAT GGTCTAATATTCCTAGGGAAACTAGCTTAATAATTAGTTGCTGCAGTTTTGTAGGTAGTA TGGGTTTTTTGTTTGTTTTTTTGTTTTGTTTTGTTTTGTTTTTGAGACAGTCTTGCTCTG TTGCCCAGGCTGGAGTGCAGTGGTGCGATCTCTGCTCACTGCAACCTCCGCCTCTCCGTT CAAGCAATTTTTGTGCTTCGGCCTCGCAAGCCTGGCTAATTTTTTTTTCTATTTTTGGTA GAGATGGGGTTTCAACATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGCCATCCA CCCACCTCAGCCTCCCAAAAGTGCTGGCATTACAGGTGTGAGCCACCATGCCTGGCCTGG TAGTGTGTATTTTTAAATGTGTGCAAAGTGGGCTTCCACAGGACCTATGTTGTTTGAATA GGACCTCTCTTGCCTAAACATTTTTATTTACATTCATTCATCTATCAAACATGTTCTTTA AAGTAACGGTGAACTCCAGACTTGCACAAAATTTTTATATTATTATAAATTAGTGAAGTT CACATTAATAAGGTTGTACGTGATAAACTCCACTGTAAATCCTGAAACATGTGCCCTGTC AAGACGGGAGAATCCCATTAATATCTAAGATTTCAAAACTTAGCAACAATTTTGGACAGG CCAAATCATAAATGAAGTAGTCTAACATTTTACCAACTAAAATTTTGTATTCTAAGATGA GGACTCACAGGGCAAAAAGGCCTTTCCTCTTGTTCTGAACAGATACCTCTGGTGCTCTGC ACTTACTAATAATCATGTCAAAAAAGCTGATGCCAATTTCATTTTTCCTCTTAAAGTCAC TCTATTAAAGGAAAAAAGGTTCTGTTAAAATTTAATCAACAAAAGCAGGTGTTACAGGGA GGGGTAGATTCGTTGAAAGCTGCCAGTGAATCCAAATACTCTCTCTTTTCCAGGCACACA ATAAAGTTAGTCCACAAGGGCACATGAAATCTTTCCAGCCCACAATCATATTAGAATTTG CATTGTGTTACTGGAAGCAGCACAGAAATATTCCCTTTTGGCTCACTTCAGTTCTTCGTC ACCCCCTGAAGCTGCCTCCTGCTGATTCGAAGGTCTTGATAGTTTCTGGCAGGACAGTGG TATCACTCTCCAGTTATATTGCTGCTTAGCATCTGGTAGTTGCAGAGGAGGTTTATACTG CATTATGTTCCAAAAAAAAACCCAATCTGTGAACCACATTAAGGCCAAATCTAGTCTTGG ATATAGTGCCATGGGGTGGGGATGAAAAGGGGATGGCAGGGATACTGACTGGCAAAAAAA CTGGAACTTGATGGAATAACATATTGGAAGAATGACCCCCATGTGTGTATTTTTGTTTTG TTATTTCCCTAGAAGTATGTGGGAAGGGAGAGTAATTAGGGGGCGGGCACGAGAGAAAAG CATACACTTTTTTATTTAGTGATATAAATAATAGTAAAATTTGGATAATCTCCTGAACTG AAGGATCTAGTTCTCTTCAACAACAAATGCTTATCAGGAATGATTTCAGCAAGATAGCAG AATAGAAGTTTTCTATCATTGTCTCCCTGTAGAAGCACCAATTTTGACAATCACTCATGG ACAAGAGTACCTTTGTGGGAGTCTGAGAGTCTAGCAGAGAAGTTCCAGCTCACTGCTGGA GCAAAAAATTTAAGGAGAGATGCATTGAAGAGGTTAAGAAGAATAGTTTCATTTTACCCA TGTCACCTCTCCTGTAAAGCAGCACAGTTCAGTGCCAGGAGAGACCCTCTTTGCCCATGA TTCTTCTCACAGGGGGAAAGTTAGTGTTGTGAATACCCAGCTTTACCAGCTGTGTAAAAT GCTGTCCAAGAAGCCCACCTCTTTTTTGACCCACCGAGAACACTGGAGGAGATTAGCATG TCTGAGTGGCTGAAAGTAGGGAAAGGTGGGGATGGGGGTGGCGGAAATCACAGCAGATAG GTCTTAGAATTCAACAGCTGTTTGTATCTGACTGACTGCATCTCAGACTCCATTAGGAGG CCTGCCCATGAGCTAGTTGGGATGCCTGACCTATAAACCCAACCAATTCCATGGGTGCCC CCATGCCCCACATGCTTCCTCCCCTACCCCTCCTGTGGCCAATTCTGATGCACATTCCTT GGGTCATGAGTACAAGCCTTTACAGGTGGTTTGTAGTCAGTTGGCTTGACTCTGGGATTG GAGGAAGGTACATAAACTGAGCATTTCAGGGCACTGCCCTAGGGAAAGCAAATGAAAGGC TCTCAGCACAAAGCCTGGCTTTGTGAGATTGAGAGAAGGTACACAATCTTAAGAATTACC TCCCAAGAGAAAGCAAAAAGAGTGGAGGGAGTGCATTCATAGAAAATATCGAGAGTGCCT CAGAATTCTAGCCAGGCTGACTGGTGAAGGAGTTCCTCTCCCCAAAGCTAGTCAGTAAAG ACTGGAGGAGATGACTACTACTTCAGATGTGAAAACAGCAACACAGGACTTCACAGAACA CACACACGCAGAAACCCGACACCAGCAAAAGAACACAATAATTTCTCAGTAACCATCCCC AAAGAAGTAGAGGTCTACAAATTACCCGACAAGGAATTTAAAAATAATTGCTTTTTAAGG ACACTTAGCAGGCTACAATAAAACTCAGTATAAATCTAAATAAAATAAAATCAGTGTAAA TCTAAATAAAACTCGGTGTAATCAGGAAAACAATATATGAACAAAACTGAAAGCTCAACA AATAGATATACATCGTAAAATAGAACCAAACAACTTCTGAAGCTGAAGACTGCAATGAAT GAAATGAAAAATGCATCAGAGAGAGTCAACAGCAGATTCGATCAAGCAGAAGAAAGGATC TGTGAACTCAAATACAAAGCATTTGAAATTATCTAGTCAGAGAAGGAAAAAGAAAGCTTA TGGGATTTATGCGATACCATCAGGAGAAATAATATATGCAATATGAGAGTCTTCAAAGGA GAAAAGAAAGAAAAGGGTAGAAATCTTACTTAAATAAATAATGGCTGAAAACTTCCCATA TCATGGGAAAGATATGGACATCCAGGTTATGAGGCTCAAAGGTCCTCAGGCAGGTTCAAC CAAAATAAAACTTCACCAAGACACATAATCTTATTGTCAATAATCAATGACAGAGAATTT TGAAAACAGCAAGAGAAAAGAGACTCGTCACACATAAAAGAAGACTGTCAGTTAGACTAT CAATAAGACTATCAGTTGACTTCTCAGCAGAAATCCCACGGGTCACGAAGGAGTGGGATG ATATACTCAAAGTGCTGAAAGGAAAAAACTGTCTTTCAATGGTACTTTACTCAGCAAAGC TGTCCTTTGTAAAGGAAGGAGAGATAAAGATTATCCCAGACAAACAAAAGCTAAGAGAGT TCATCACCACTAAGACTGCCTTACAAGAAATGGTAAACGAAATTGTTCAAGCTGAAATGA AAAGACACCAATTAGTAGCATGAAAATATAGTATTTTTACTCCCTGGTAAAAATAAATAT GTAGGCAAATTCAGAATACTCCAATATCCTAATGATGGTGTTTAAATTCATTTTAACTCT AGTATAAATGTTAAAAGACAAAAGTATTAAAAATAACTATAGCTACACCAATGTTAATGG AGACACAATATAAAAAAAGTAAATCATAACATCAAAAAAAATGGGGAGTAAAAGTGTAGA GTTACCAGCTTCAAATAGACTCATAACTATAAGATGTTTTGTGTAACTCCATTGTAACAT CAAAACAGAAATCTATAGTAGATACACAAAAGATAAAGAATCAAACCATACCACTATTGA AAATCATGAAATTACAAAGGAACATACCAAGAGAGGTATAAAGAAACAAAACAACTGCAA AACAATCAGAAAACAACAAAATGGCAATAGTAAGTCCACAATGGAATGTTATTCAGCCTT AGAAAAAAGGACATACTGCCATTTGTGACAACATGGATGAACCTGGAGGACATTATGTTA AGCGAAATAAACCAGACACAAACAGACAAATACTGCATAATATAACTTATATGTCAAATC TAAGAAAGTTGAACTCATAGAAACAGAGAGTAGAATTGTACTAACAGGGATTGAGTGTGA GGACAATGGGGAGATGTTGGTCAAAGGATACAAACTTTCATTTATAAGATGAATAAATTT TGGAGACCTAGTGTACAGTGTGGTGACTATAGCTCATAATATACCCTTGAAATTTGCTAA CAGGGTAGATTTTAAATGTTCTCAACACACACACACACACACACACACATGCACACGCAC AGAGGTCAGTATGTGAAGTGATAGATATGTTGATTGTGGTAATAGTTTTATAATGTATGT GTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATAATCACAGTATATA TCTTTAATAGATATACTTTTTATTTGTCAATCACTCCTAAGCTTGAAAACTCACCATTTT CAAAGCAGTCACTCCTTTCATGTCCACATTTCATCAGGGAATGATTTTGTCCCATTATTA ATATAAGTACCATTTCCCATATATTGTTTGATTTAAAGATTTCTGTTTCTCCCATGTTTT CATTGTGCAGTCTGAACTACTATTGGCACAACTATATTTACATAAACAGTTCTAAACCTA GGGATCAATTATTGTTATTTTTGTTTAGAAAATATTTTTATGAATATCAATGGCTTTTTC TTTTGAGATTCTACTGTATTCATATAGTGTACTTTACTACCTGTACCTTATTTATATTTT ACCAGCTAGGGAGCTGAGGGGAACTCAAAATATCCAAGACTTTGGGCCTAAATTTCTAAA AATGGTCATTAAAATAGGAAGTATTAAAGGAGTGTGGGTTGTGGACTTTCGTACTGATTA GCATGAACATTTGAAAAGCGTAAAAGTAGTGCTACAAAATATTTCAGGTTTACATATCTT TATTATATGTTCAGTCAAAGCTGTCAAAATCGGTTCTTACAGTTTTAATTATAATTGCAA AATAAAAATTTTATAAATTTCGGTGTAATCTTTTATAATCTTTAGCAGATATAAGTTCAT TTAATTTATTTAGAAGTGTTGCATAAAACTCCTTTGCTATATTTTCTAATATGTAGGTAT CATTGAGAGGCTCTGCTGTGAAAAAATATATATTGTAGAAATGTTAGGAATTTGTGGTAA ATTAGTCTTCATTGATTTTTCAGGTTTTAGAATTTCTATTGAGTCATAATATTCTAGTCT GACATTTTTTCTTTTTTTGAGAAACAGTGAGATGATGGCAAAGTGAATATGTCCCATTTT TTATTGCTTTTCATCAAATGTTACTTTCTCATAAACTGCAGAGTGAACCTTTCTCCACCA AGTAATTATGCTGATATGTTGTACATTCTTAATACTCCTTAAAAGTGAGGGAAAATAAAC ATATCAAATGTCAAATAGTATAAAAAAATTTCTCTACTAATCTGAGAATAAGAATTATAT GTTTGGATTCCCTTGATCATATATCTCTTTATGAGGATGGTACCAACAACCCAATAGGAA TTTACCATAAAAAAAAACACAAACACTGATATAATACAACTAATATAAGACATTTTATTA TAATTTATACTAAAACCATAATAAAAAGGTTGTTTATACTTAATGGGACAATCCAGGGAG GGGAGGAATACAAGGCTGAACACCAGTTGATATGAGAAGGCTCTGAGATTTTGGTTGTTA AAAGTCACTCTGCACCAGCATGTGATGTGTCTGCAATGCTGTTATAAATGCCATCTTAGG CAGATTTGACAGAGGGATTCGGAGATTATGTAGACCTGTTGGGCTCTGCTAATCAGAAAA CATCTCTAAAAAGATATAAGAAGAAATAAGAGCTGAAATGGTAACTATTGTCGTAATCCT TCATTTAGTTACTAATAACTAACATTTATGGAGTATTTACTGTGTCAAAGACACTGCTAA GCCCATTATGTTATCTTACTTACTATGATTTAATCCTTACAACAATCTATTTCTATGGAC ACCTACTTTATTCCATAGCCTATGCTAGAGATTGAGGATTCAAAAAATTAAAGTTGCCTG ACTTAGAGTGAGTTCACAGAAGGACCCACTGAGAGAAGTAGGGTGATTGATTGCCCAAAG AAAAAGTGATTGAGAATGTAACAGTTGGTGGCTGTGCCAGAGTCTGAAGGGCTGTCATGG ATATGCTAAGGGGATGACATTTTTAATATAGAGGAAGGGGGAATAAAGGCACAAAAATTA TGAGGAAATAGATATCAGTCACTCTAGTGAAATCCAGATAGTTATCTAATGCTTGTGTTC TAAAACTTGATACATAGTCTGTTTTGTGAGGGGTATAAAAACTGGGCACAGTGTCTCCCA TTAGATCACAGGGCCTACAGACTGATGAAAGCAGGTATATGGATAATGGGGTAGCATGTA ATAGGCCTTTTAAGGGAACAAGCAGTGTCACGGGAAACCAGCGGAGGTAGAGATTTACTT TGCACTGGAGGGGCCTGACAAAACATGACATTTGTGTTAACCTTAATGTGGTGAGGATTG GACTGATGGAGCCAAAATAATAGTACAGTATCCAGTGGTTTCAGGAACAGAAGCATCAAG ATAGGAAATTATAGGACATTTTGGTGCAATGGTGAGTATTTTGGTTTGGTTGTAGTGTGA ATTTTATGAAGGGAAATAATGGAAGAGAAAGCTAAACAGCTGGGCACAGTCCTGGTCATG AGGTCTTTGAAAACCACAGCAGACAGTTTGCAATCTTAATTCTGTGTAATTGGGAAATCA TTGAAGGCTTTTGGGGAGAAAGATGGTTTTAAGGAAATGATTTTTTAACAGCTCACCTTT GCTTTTTGATAAAATAGTTTTCTCTCTGTCACTAAAAATGTGTCAGTTTAGATGATAGTT TAGGAGGAATGTTACATAGAAGAAAGCATGCCAGGAGTGGGAAGTTTTTACATCTGTGCT CATTTACTGGCTTGGATCATGGTGTCATCTTCACTGTGACTCCAGTTTCTAGCAGTGTCT GGCCCACAGTAGGCATTCGGTGAGCCTTGGGGAAGGATGTAAAAGACAGATAGAACTTCA AGTTCCATTCCAGGTCTGAAGTTCTTTGATATAATTCCAGAAGTTAACATAGCTTCTAAA ACAAGATTTCATACAAAGATCTAATTCTGTAGCCAAAGCATAACAGTTGTAGGATTTAAA CTCCAATAAAATACACAAGATTTTTTTTTAAAAAAAGAGCAAGAGTTAAACAACAATTAG ATTCAGTTGTGGCTTCTCTCACTTGCCTCTATTGTTACTGTTTTCTCCTGTGTCTCTTAT AATAGTAACTGAAAGGAAGTAATGATTATCTCAAATTTGGTGTTGTCCTATTGATTAGCA TTCACGTTTTAAATATAATTGCTGACATTATATTAAAAAATATAATTGTTGAAAATTTCT GAACCAAAGATAAATACCAGCTTGTAGTAATGCCAAACCAAAATTGAATCCTTTGAAGGT TTCAAAATCTGTTCCCTGAATGTCTGCAAAATTCCACACTACTTACAGCAGGACTTAGCT TTCTTAGCCTTTCTGAAAATCAGTAGATACACTCAGAAAAGTTTACCAATGCACGTGTAC ATAGTCTTTGGATGCAGTTATAGGCCGGTTTGTTTACAGGCCCAAGAAGATAATCAATAG ACATCCCCACCCCTCAGTTGGAAGCAAATTCAGTGGTTACAGAAATCTCACTTCAATGTA TTTGAGGTTTTCGCAAAAAAGATGTGTACTGCATATATCTTTAAAGCAATGTTTTTTGAG ATGGAACATACAAATAAATGCCTTTAGAGGTAAAAGTTGTATGGAAGCCAAGAAAATATT AAAGAAATTCAAAAATGCTGCTGATCCACACATATTTCTCAAAGGTCCTATAAGCATTAC AACACATTTATCAAAGAACATTTGAAGGTGCCAAGATACTTCCAGTAATAAGCGTGATTA TATGATTAAAATGCATTTGCATAGCCTTTGGGGAAATGGAGGAGGGAGACAAGGAGAGAG AAAATAAAGAGGAAACTGCATTAGTGATTCTCTGCCGTTGTTGTGAAGTTGACTTGTAGA AAAACACCAATTTTTCTAAAAAAGTGTATGCTAAGACCTAAGGAATATTATTTTTAACCT ATCTAACGTATGGAGTTGACCCCCTAAAAGTTAGTGCTTCTGTGGAGAAAGGAGACCAAC ACAAATCTTCACCACCCCAACCCCTGCCCACACACTTTCTCGTTAAAAGAAGAAAGGAAT TGGTGGAATGGGTGTTGTGTCAGTCTCACTCTGGCAGAAAACAGAGTTAACTCCAAATGG TGTAAGAAACTCTAACAACGGGGCTGTTTACAGTAGACAGGGTTAAGTGAGCAAGCAATG GATATTAATAGATGATGAGGCACAAAAACTGGCAACAGCTGGAAGCCATTATCATCACCT GAGGGCTGATGGGGCAAGGGGAGGACAAGGTATTGTGGGAGCCCAGTGAAAAAGGAAACT GCCAAGAGACTACTCAGTGGAATTGCAGTCATGGAGCCATGCAGCCACTGCCAGGGGTGC TGGTCCAGCTTGCTGGGCACGAAGCAGGGCAGAGCCAAAGACAGAATAGCCCCAGGGCAG GGGCAAATGGCGCATAACCAGGTACCGTTCTCAACTCTTTGACTTCTCTGCTGAGAAGAC AAAACATCTTTTAAGTTGCCATCCTGGTGAAACTATTTGTTACGAGGGTACTGTTCTGTG AGGTTTTTATTGCTTAACGTTAATAGGCGGCTTAATCACACCCTGAGAATAATACCCAAA TATTGCTTTTCTAAATGTCCTTGTTTGGGAGACATTGGAAAATTCTTTAAAGAAAGAGCA GTATACCCCCACTACCCAGATTGTCCTTTTTTTCCATTTATTCCAGAAACCTTTACTGCA GGAAAAGAGAGATGTTGCCATAAATGTTTGAAAGAATTCCTTGTGTAGTTAGTGGTGGCC ATAAACATATGGCCTTCACTAACTATTTGCCCTCTGTTCCAACCTTGTCTTTCCATGACA GTTAACCCCATCATTACGTATTCCTGCTCCAGTTTCACTGGGGAATTCTGTATTCAGAGC CAAAGTATGTCAGTAAAATATTAAAAGTAACAGCACAACAAATAAAAAGAGATAAAGTTG AGAAACTGCATGGCAAAAAGCCTGTCACAGAGTTGTAGAGAAGAAAGAAGGAACTTTTTT TTAGCTAATTGAGAAAGCATTGTTGTCATTATTGCTAACATTTAAAGTTCTCAATTTTTA AGGGAATTCTTGAAACATTGTACTGGGGAAAACAGGAAGTTCTGACTTGAATACATTTTT TAAAGTAAAGGATGTAATTTGAGTGAATTGATCTCAGACTTTACAGATGATCTTTTAAGA TATGAGTATTTTTTGTGCATTATAAAAGTATAGTTGTTCATAATGGAAAATACAGAAGCG CTTAGAGCATAAAATAAAATAGAAATTACCTGTGACTCTGTTGCTTAGAAGTAATCACTA TTAATTTGGTTTTCTTCTCTTCTTAATATATGTGTATTCTTAAAATTATGATATTGTGAT CCTTCATTGATATTTCCAAATGACTTTCCAGATTTTCTCCACTGGTTTTTATTTCCACCA AAAGTATGGGAATTTAACTGTATCCTTCTTGGGCTTGAAATTTTGAAGACCTTTGCCGAT TTTATTTTAAAAAGTGATTAGTAAGGTTGAACTTTATTCATAGTTATATATTTATCATTT TGTATTGAATTATTTATCCATGTCTTTTGCCCATTTCCTTAAGGGACAATTAGTATTTTT TAAAATTATTTTTAGGAGCTCTTTGTATGGGAAGAAATTTCAGAAGATCATCTTTCTTGT TAGAAAGGATAGGACTAATTGGTCACCCTTATCAGGTGATTATTTGATGCAATTTTTGAT GCCTTCTTGCTTTTAGAAAAAACAGTTTTAAAGGACTAAGCTCAAAATTTTTGTTATTTA AGATATTTAAGGGCTGGGTGCGGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAAGCCA AGCTGGGAGGATCACTTAAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATGGAGAAACT GCATCTCTACTAAAAAATACAAATATTAGCTGGGCATGGTGGCGTGCACCTGTAGACCCA GCAACATGGGAGGCTGAGGCAGGAGATTCACTTGAATCTGGGAGGTGGAAGTTGCAGTGA GCTGAGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCAAAAAA AAACAAAAAACAAAAAACAAAAAAAAACAAACAAAAAAAAACATTTAAGCAGGAACTTTG CCTTTGAATAAGTGCTTGATGAATTCTGACTTAGAAATTGTTAGCTCTTAGGTAACTTTT AAGATATTATTCTTAAGAAAAATAAAGGATTGTTTTGAAGTTATTTGACAATTAAAACTT TATTCCCATCTCCTCGCCCAAAGATATAAATCTCTTAGGACTGAGAGATTAGGATCCTTC ATTTCTACTTTATGAGAAAAACAAATAATACACAGTTGGGGTGAGGAATAATGCACAGTT GGGGAGAGGAATAGGCATATTGTGCCAGTATATGTGGCTTCATGAAAAAACTATTAACAG CTGTTGTTAAGCTAGTCTGTAGAAAGTAGAGTGAGAAGAAGGCAGATAGGCATTTTGCAA GTGATAATTTTCTTTAAGGACCACTTACCTAATATTAGGCCTTTTTAATTTTTGTGAATA TTACCAACTTTGAGATCACGAACAAGCTTGAAACACAGTCTTTAGCACACAGAGTCAATT GAACCTATAATTAGCTGCTCTTTAGTGTAACATATAAAAGTTATATGTAACAAGTGTAAC ATACAAAACAAAGATGAGAAATGTAAAGAATTTTAATGCCAGTCTCAAGTTGCTAAGTTA TTTTTAGAATCGAATTCCTAAAAGTTTTGCTGTTTCCTGCATGTACCTGTAATTGTTCCT TGAATCTCTTCAAGAGACAGGTTTTCCGGTTTCTAAATTCTTATCTGAGTAGCTCAGACA TAAAGAGATCATGTATATGGTATGATGTGGTCACCTTTTTATTTACGGGACTTTCTTAGT CTAATGTGTGTGAACTCTTAAATGCATAGTGTCTTACTCTGTAACAGCAACCAGCAGTTG TGTGTTAAGATTTTTCACGAAGAGTCCCAGCTGTTGTAAAAAGGAACAATCTGCCCTGGC TACAGATTACAGTGCTTTGGGTTTAGACTGCAGGCAATACCTCTGGGACCTGTCATGCAC ACTGTGAACATCAGTATTCCTGGGAGAGAGAAGGCAAATTAGTCACTTCTGGCTCTTAGA AGTTCTTGCATAACTTGCTGTTATCTCAGTACAATTTCCTGGGGATGCTTTATCCTGGCA TGTGCCCCCTCCTTTATCAAAAGGACCATTGAGTATTGGACTGGGATGCCATTGCCATTG CAGAGGGCTGGTGTTGTTTCCTCCTCTTCATCCTGGATCCTCGCATTATTGTTTTTGCCA TGTGGGGTGTCTTGGCTTCGTCTCCACCATCACAAGAGTTGCCCATCTCCCTCTCATACT TATGTCAACGACCTCCCTTGCAGTAATCTAGCACTACCCATGCTTTCTGTAGAACTGTTA TATACAAACCATTCTAATGATTCCAGATTTCCTCCTGGCACTTCATTTTCTTTCCTCCCC TTCCCAGAATCCTCTTCCTTATCTCTGGAATATAGAGCTCAGATGCCAAGAGGCTGCGGG AAACTAATTGAGTTAGGCTTTTTGTTTCTTTCTTTTTCCACCCTCCGTGTTCCAAAGCTG GATTTCTCTTATGCTTTGGATTTTTCCCTGCCCTCCTCCTATCTGAACAGCAGCTTTCAG ATTATGTCTGGGGTGTAGTTTACACTATATAAGAGAAAGTGGTTTATAAGATAAGGTAGT TTATCCTTTTCCAATTCTCACACTCCTTAAATACATCTGTTGTTGATTATTTCATCTGGT ATGCCTTGATTTTTGCTTTCTACTTTGTTTGCATTTCATTGTTCTTCTCTGAGATTATTT CTAGACTTTTTTGCTGAGCCCCCATAACTCTGTTTCTGATTAAGTAAACAGCTTTGATAA GTCACAGTGGAATCTTAACACAAACTGGCATATGCACAATTTACCTCTTCTCTCCATTAA GCTGCATTTCCTCCTGAAGTTGAAAAGTCAGTGGAGAATAGTTCTAATAGCCCAGCATCC TTGTATTTTAAACTCTTCCATCGCTGATTATATTGGAAATACTGGTATTCCATCACCAAA AGCTCTTACTTATCTTCCAGCTAGTTTTGAATTTTCTCAAGTTGGTAGCTCTTTTTTATC CAATTGGTAAACCATTCACAGGCTCCACCTTGGTATGTGAATGGACCTCCCACCCTTTCC TTGCATTCAGCAAGAACCTGCCTGAAGTATTCATTACTGTAGCGATGAGGGCACCTGCTC CCCAATCATTGCCAAAGAGAGCTGAAAATGCCTAAGGAATTTGCCATACTTGGTTTCTTA CAATTCGCTCACGTCACTCCTGCCATTATCATGTCAAAAATACTCTTTCTCTGTTAAATA TTAAGTTTCATTTGGAAAAAAAAAGAATCTTGATATGAAGTTGCCATGGGACCTCACTGT GTATAGGTTGATATGGATACTAATGGTAACATTAATCTCATGAAAATTAGGTTTTTGAAT TTAAAATACATTTGTTTTTGCACTGCTTGCTGTCTGTTCCTCTTCTCTTTTAGTTGACTA GTAAGGAGATTATTTTTTCAGTTTTAAAATAAGATATTGGCTGGGTGTGGTAGCTCATGC CTGTAATCTTAGCACTTTGGGAGGCCGAGTCAATGGGTTTCTTGAGTCCAGGAGTTTGAA ACCAGCCTGGACAATGTGGTGAGGCACCCCATCTCTACAAAAAATTAGCCAGGCATGGTG GCCCGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCGCTTGAGTCTGG GAGGCGGCAGTTGCAGTGAGCCGAGATCACACCACTGCACACCAGCCTGGGTGACAGAAC AAGCCTCTGTCTCAAAAAAGTAATTAATTAATTAATTTAATTTAATAAGATACATAAAGA TGATTTTATGCTTTATCCTAAAGCAATGTTCAGGTAAGCCTTGAACAAGTGGGGTCAGGG ATGTTGACCCACCACACAAAAATACACGCATAATTTTTGACTCCCCAAAAACTTTATTAA TAGCCTGCTATTGACCAGATGCCTACCAGTAACATAAAAGGTTGATTAGCATATATTTTG TGTGTTATATGTATTATATACAGTAGTCTTAACAATAAAGTAAGCTAGAGAAAAGAAATT TTATTAAGAAAATTATAAGGGGGAGAAAATAGATTTACTGTTAAGTGGAAGTGGGTCATC AAAAGTCTTCATCCACATCGTCTTCACATTGAGTAGCCTGAGGAAGAAGAATGAGGGGGA GTTCATCTTGCTGCCTTAGGGGCAGCAGATAAATTCTGACTAAGTGGACCTACACAGTTC AAATCCATGTTGTTCAAGGGTCAACTGTATTTAGTATAGGGAAGGCCTAGAGCAGATGGG TTTGTTCTTTATTCTGGTTATATCACCTGACATGTTATGGCTGCCCACTAACGTTTTGCT TTAACTATGTGTGGCTTGGGCTCTTTTACTCCCCTCTTGAAATATACTTTGCTCTTTTAT TAGAATTCTTACTGTCAAAGAACATTCCTTGAAATAATCTGGAATCCATCTCACTGGCCA CAAAATAAATGTAAAGTGCACAGGCTTCTAGTCGTCCTGTTTGCTCTTTCAAAATCATTT CTAGTCAGGCTTAATAAGTCAGTTCAGGTGTTCTCCATCTCTTGGTAAAGTATGTATTTT CACCGTAAAAAAAATGTGATGTTGGTATGTTATTTGGCCCATGTACAGTTTTTGTTTAAA AAAGAAAGTCAATTTCTTAAGAAGCCAGGGGGAAACATGTTTCACCATAAAATATGGGCA GTGGCCAGTTGACTATGAGTAGAATTCACTTTTGCTGATTACTAAAGTGACTTGCCAACC TAATAGTCATCAAAATAGAAGCCATATTAGATGGCTCAGATAGGGTTTGAAGTAGACTCT CGTCTTTGTATGGGGTTGTCAATGCATTTGTTTTGTGCCTAAAAGCACATTATTCAGGAA ATGCCACTGGGGTGAACACTGCCTTTCATCCACTTTGATACAAAAATCACAGATTCTTAA AATGTGCAAAATAAGAGGAAAGCCAGTTGTAGATATGTCACCAGATTTAGGCTAGTTTAA GCTTCTTGGAAACATTTTAGATTTTAAGTGAGCTACCTACCATGAGTTATCAAAAATTGT AAAATAAAGTTGCTTATTAGTTTAAGAACCTTATAGTACTATTTTATACCAAAGAAATTT GCATTTATACAGAAATACAGCAGTGATCTAACTGAATTTCCTCATTTATTTTTTGAGGAA ACTATACTTGAGTGATTCAGTGACTTTTCCAAGGTGACAGAGTTTGTTTATGGCTAAATT GCGATTAACTGTAGACACCACATATTTTTACCACATCATAAAGGAAATCTGTAGTCGATT GCCACGTTAAAGGCATTAAAAAGTAATAAATTCTGTGTGATACATTCTGGCTTTTCCTAG CTTTTCCCTATATGATTCCAAGTGAACTAACGCCCTTGAGAAGCCTGGGGCTTTTTCTGA CACTTTTTTTTCTTTCTGAGATTTTTTTCACAAAATTGTAAGCCTAGGGCTACATTCTTT CTTACATAAAAATTTTGGCTATTATTACTTTGGAACTACTTGCCGACTGTTGACATATTC CCAATGGTTGCAAAGAATCTCAGAAGAAGTTGGAGCTGCGCCTCAGTGTTTGTCAACACT GGCCACTCTTGACAGATCCAGGCCCCAGGTAATGCCCGTCTTGATTATATTGTTTCAGAA GTAAAGCGCTTTTGGAAGAAATTAACTTGAAACAAACGTGAAAGAGCTCCACGCCAGGGG AAAGTAAATTCTGTCCACTCATCTGTTTGACAGTTTTGTTTATGTACATAAAATGTACCA CAGCCATCCAGATTTGAAGCCATTTATAATATATGGAAATTTTCCCTGTAAACAGAAGTA CAACTCTGATACGATAACTTTTGTTTTGTTTTTATTGTGAGTGGGAGGCGGGGAGGTAGT CAAACAAGGGATTTTTCTGTTGTTTTCTGTCTCTAAATGTACATGCCGAGGGTGGAAGAC ATACTGTGAATTTAGGGGGTTGAATCCTGTTCTCAGCAGCACTTAATCATGGAGACAGGA AAGTGGCTACAGATTTTTGATGAAAGATTGGCCTAAATTCATCATGTGTCTATAGCACAT TACTCTCTGTAGCATAATAAATGCAAATGGCTGACATGAGTATTTTCTGCAGATTTTGCT GTGGAATAGGAATGAAGTGGGAAGGAGGTTTAGGGGCCTGAAGGAAGAAGGAAGAGGCAG TAAAATATTCACTAATGTTTCCAGGGGTGGGAATGTTTCCAAGGATGGAAAACCACAGAG TAGAAACCAGAGTACCAAGAGATAATCTTTTAAAAGCATAACTAAACTTCACATTAAGTC ATAAAAACATTCAGTATTCTTACAATAGAGTAAGGTAGAGAAAATAAAATTTTAATTTTA AATATTGAAATACTTTATTTTTATTGAAAATATGGTTTTTAGCGGGTGTCCTTACGACAA TTGTTGCCTTGTTAAGTCCTTACAGATATCCATATGAAAGTCACAAGAACCTTTATGTTC AAAGGTTTAACATTTTTAAAAAGGGGCATTTTTTTCTCTTTGGCATTATTCACATATAAA ATACCCATTTCATATGCATTTCCATTACAGCTTCCTATTACTTAGAGAAGGTTGGATTAC CATCTGGTCACTTTCTCTTCATTAGGATGACACCAGAGGGATGTGAGCAGACGGGTAGGA CAGGAATCTAAAAACCAAAAATTGAGATGAATATCTGACAGTTTTTTTGTATTTTTAAAG AGGTGCTAAGATCAGAATATTTGAACTCAGAACTTTTTTGGAAAGTACCACACACACAGT CACCTAGGATATGAGCTTTAGACTCTTTCTATAGACTTCCATCTCCTCTCTCTGTATTTA GCCATTTCCTAAATTATAGGTGCCATCCGTTCATTCAGCAACAGCTTATTGAGTATCTAC CACTTGTTTGGCACTGTGGTAGTTACAAAACCAAATTAAACATGACCCCTGTGTTCAGGG AACTTGAGGATTGGTTTTAAAGTAGTAAATTTTTTTTTAAGAGTAAATGTCTCAAAACCT TTATGCCTAAATTGAGTTCTTCAAAGCAATTAATTTTGGGAGGGAGAAGCTCTACGCTTA TTTCCTATTTTTCTGTTATGCCATCTTCTAACCCTCTTTATAGCTGACTTTTTCCTCAAT TTATGTTTATTAATGTGGTTAATACTTTGACTTTTCTCTGTCAAGTATTTGCAGAGTGGG TCTAAAGGAAATCTTAATCCCTTTTGGTATTACACAGACATGTTTGAATTGTAAACTGTT AACAGTCATTGAAAAACAGAGACCTGTATTTCAGGAATTGAAATGAATAAATTAAGATCA ACCTGGAAAAAAGGACACATCTTGTATGCATCTTTTAAGCAAGAGCCAAAAAGGGAATGA AAAACACAATGCTGCTAGCCACTTTAGCAATCTAAACCAGAATTTTGTCATGTTTGTTTT TCTCTGTCCTTATTAAGCTTGACTATTTGAAGAACCACTTTCCAAAAAAGCACTGATTCA GACCCTGGAGGTAAACGTGTTACATGTTGGTGACTGTCTCTGCATGCATGCTCATGTGTC TTTGTGCCCACTGATAATTTATATTTTTGGTCACTAGATGGTGCCCTTTCACTTTGAATG AAAGTGTATTTTCTGTTGAGGCGTTTGCTTTTTATTTTGCTTGTTGTTCTGTTGATGCAA AGATGGTGGAAAATCATCTTATTTCTTGATTTAAGAAAATCACATTCTCTCTTAAATCGG ATACGAGGCTCCCTGTCCCTCTATGTATGCATAGGAATTTTAATGCGATTATCCAACCTG TAAAGTCACACATTTGTAGATTATCATACCACTCAAAACTTACTGTTAATTTGTTTTGTG GGAAAAATACAAATTTATCCTATAGAAGCATTTTGTATAATATATATAGGACCAATACAT AAATGACTACAATTGAAATATCTATGTGGTTCAATCTGCTGTTTCTGTACTTGAGTTAAC CATCACTTGGAAAGCCAGTGAAATGCCAGTTACTGAGTCCTGAAGGCCCAGAAACCTGTA TTTTAACAGGCATGTTTTGAGACACATTGGCTTCTAATCACCCACAGTAGTAGTGAACAT TTTCAGTAGAGGTTAACTTCATTGTCAACCAGCAGTAACTAAAACCAAAGTTAAGGATAG TTGAGAGTGAAATTTTGAAGGTAGACAGCTCTTTAAAACCTGATTGAAGGTAGACAGCAA CTGGAAAACCTGATTGAAGAGGGAATTAAGGAGGCTAGTCCCCACCCTGAGGCTTTGGCT TGGTATCTCCCTCTACCTGGAAGGTTCCAGCTCAGCCAAGTATCCTACCTCCTTTAAGCC TATTGCCTAGCCGAGCTATTATGGATGAAATAAGAATTATTGAATAAAATGATCTGTCTG TTTACATAAGTGTGGTAAAAGTTGGCTAGAGTATAACAGAGAAAGGGCAGTCCTGGTTCT TGTTAGGATGCATTAGAGAGCAAGCAATGGGAATGAGATGCTGTTGGGCTCTCTCCCAAC TTGGGTTGGTCAGACGCCCCTTGTGCCTTGCTGTTAGGCCCCTCATTTCATAATAACTGA TGCTTAACATTTTGGCAAGTTTTAACCACTCTTAAGACCTTTGACCTTCACAGTGTCCCT GTGACAGGTTAAGTGTCAGGGGAGGGATTACAAAATAGGATAAGGAAGGGTGCTTGAGAC CAAGAGCAGCCACCAGGAGAGGGTGGGGGCTGGAGGTGGTGACAGAGACTCAAATTAGGC ACAGCTGCTGGACATCTCCCCAGGAGGCCAGAGGCATTCCTGAACTCTGAAGCTTGGTGC ACTGTTATTAACTGTGATTTCACCATCCTGGTCCTAGCAGTGGGTAGCTTTAAGAAAAAT CGTTTCCTCCCTTCTTTCCTTCCTCCCTCTTTTTTGGTGAGGGGAGTGGCAATTGCCCAA TTGCAACATAAGAATATGATATGCTCTCTGTGGCGTTTTCACCTAGGCTGTGGGATGGGG GTGGGAGATCACAGTGTCAGGGGAGTATGTGTGGTTTAGATAAAATCCCCACCCAGTGAT TCTCATGCCTTATCCTAGAGAATAGATGCTTTAGGAGTTAAAGGATTCAGGCGGAACTGG TGGTAAATTGTGAAAGGTGTGAAAGGTGTGAAAGGTGCTCAGTAAACATTTACTGACTCT TTACTGCCTGGATGCAAAGTACAGGATATAAAAGACTTAGCCAGTACTAACTGACTTTCT TAGAAGTCAGTACATTGTAGACACTCAGTAAGGTTGAGACATGATCAATGGTTGTGATAA TCATAATGAATTATCTCTATGTTATTCAGTTTTATCATAAAGCTGATGGGTATAGAACTT TTGACTTATCCTAGAATGATCTTGATCTGTGTCAAAGGCTGACCTGTAAAATAAGAGAAT ACCTGGATTGCTGGGCAACTTGAAAACCTGATTGAAGAGAGAATTAAGGAGGCTAGTCCC CACCCTGAGGCTTTGGCTCTGATATCTCCCTCTACCTGGAAGGTTCCAGTGTCTTACCTC CTTTAAGCCTTTACTCATATCTCCTTTTCTCTATGAAGTCTGATACTCCTCAAGACTCTC TCATAGCTGGTACTTCCTCATCTTTTTGTGTTACTCTTCTTTTTCTTTTTTCATAACATG TATGTTCTGATTAATTATTAATTAGATAATTTATTTGATTAAATTATATTTTGTCTCTGC AGAAGAGCCAAGTTCTTTGTGGACAGGACTCTTGCTTCTTCACTTATCTCTTCTCTCTAG TCCCTGGAACAGTGCCTGGTACATAGTAGAAGTACAGAAAAGATTTGGTGAATGAATGAA TGCTTTCCTGTAGAAAGTTTAATGGCAGTAATAAACAATATTAGTCACTCAATACTAATT CTGGATAAATATTGAATTAAATATTCCTGAATGAAAGTTAAGGTTTTTTTTCTATTAGCC TTCACTGTGGTGATGTCTTTTAAATGAAGTTATTGCATAAAGTGTGGATCCAGAGTTGGA AGACATTGGATTATAATGTCCAAGCTTCTGAGTGGTTTTCTGGGAGAAGTTACGAAACCA CTCTGTGCTTTAGTTTCCTCTGTAAACAACGTCATGAATCTGTGCTGTGGATTAAGTGAA TTGATGCACTTCAACCCTTAGAACAGGGCGGAGACTTGTAGCAGAAGCTCAATTAATAAA TCCAATTTATAAAAAAAAATTATATGATATTTTTATTTTGCAATTACGTGATATACTTAT TTTGTAAAAAGAAATGTAAATTTAAATGGTTTAGCCAATTTTAAGGAAGAAAGTCACAGA TAAATGAAAACGTGGGCATTTTCCATATTCCTGTTGTTGTTACAATAACACACCTAGAAT TTTATTATAATAATAATCTCCAAATGTTGAGTTTATTATGGAACCTCTTATGTTCTAGAG TCAATTTTAAAACAGAGTTTTTAAAACAATTTTAAACAGAGTTTGGGAGTTTCACACAAG CCTTTTATTTCTTTCTTATAGATCCCCATATTAAGGTTTCTGGAAAGAAAGAAGATGTTA AAGAAGCCAAGGAAATGATCATGTCTGTCTTAGACACAAAAGTAAGTGAATGTTAAGGAC ACTCAGATGTCAGAACCTTGTCTCTACAAGGGCTACTTCATGCCGTTATGAAAGAACCAT TTGGAGAAGAAAAACCAGGAGAAAGTAATGGTGGGTTTTAAAATAAGCACATGTGATTCT ACAGTGGATGTAAAGTTCTGTTTAATATTTGAATAGGTTCTTTCATGCTGAGTAATTGAA CTATACATACACACACACACACCTATATGTACCTACATCTACATACATATATATGTATCG TGTATGTATGTGTATATATGTATACATGTACATATATACCATCTTCAGAAATAGAAATTG GCCCTGATTAATATAGGGTAAGTAATAAGGATTGTAGGAATTAGATTATTTGCTTTTATG ATGTCAGTAGAATACCAGAATGATCTTCTATATAGCTCTGTGTTGGGTGTGTGTAATGGC ATGAAATTTGTTGCTTGCTTTTGTGTGATCACGTGATGTCTCTCTCTCTCTCTCTCTGTA AGTATATGTATAGAGAGAGAACAGGGAAATTTCAATATGTAAAAATTTATACTCATTTGT GAGAATTTATTTTCTTTAACAAACACATCTAAATCACTTATTGTATACCAGGCACTTCGC TAAGTACTCTACATTTTACACTTATTAATTTGTTTGATCCTCGTAACTGACTCAGCACAA AGGTATTAAGTAATTTGTTCAGGACCCTAGAGCCGGTTAAGTGGAGAGGTGGGATTCAAA TCCAGGCTGTCTCATTCTTAACCACTTTGTCTTGCCACCTGGCATTTCATTAGAATGATC TCCCTCTGATCGCTTTCTTGTTTTCATTCTTCCTTTCTGTTCTTTGTTGGTTTTCTTCGT TTTTAAAAAAATTACTCCCCTGATAATTATTAAATAGTTTAGAATTTTCTTCAGGAAAGG GGGATTTTTTTGTGTTTTAAAGGTTAAACTGAAAGAACTAAACTTAAAAATCAAAATATA TTTAATGGGCATAAATTTAAAACTTAAGAATTCACAAGGTATAAAAATATTTTTGACATA TTTTGATATTTCGATTTTACTTTTTAAAGACTGAATAATTTCAGTAACAGTCTTCTAAAT GAGAAGGGATTTTATGCCAGTCTTTATGATTGTACAGCACTAAATTCCTCAAATATAGTC CAATATGACCACAGCATTTTTATTTATTATGTCTTAGAATTTTACATTTTGCTTTAATAT AACTAATGTACTTTGAATTTCTTTATTTAAGCCATTTTGTGACCAGTTATCTGCACTTTA TGATCTCTTTCTCCCTTCTTTCTACCAGCAAGAGTAATAGATCTACTTTGTAAAGTTCAA TATATAGTAATACAGGAGTTGGGAAAGCAGTGATTCTAAAAACTTTCTTATTCACAGTTT TGAGCTTTATTATTTCTAATTTTGTATCATCTTAGTTATGCAGTCCCACTAGCATGCATA TCTTCAATCTTGTAATTGTGTTTTCATCTGTTTTTAGTTATTTGAATTAAATGTTTCGTG AATAATGTCTTTAAAGACAAATTGAGTAATTTATTTAACTGTAGCTGACTTTGTTTAAAG ACTTCTTTCCAAAAAAATTATCTTGGTAAAGAATAAATTTTTCTATTTCTTCTGACAAAT CTTTCTTAAAATGAGAATTTCTTTTTTTATAATCAGAGAAATTAATAGCAGGAGAACACT TATAGATTAAGATGATCTTATTAAGAAATAAGATTTCCCACTGACTTGCTTTTTGTTAAT ACCATTCCCTTGAGGGAAAGACATTTAGGAGGTCATTCTTTCCTTTTGCATACATCAAGT AATAATACATTATTTTCACATAGAGCAATCGAGTCACACTGAAGATGGATGTTTCACATA CAGAACATTCACATGTAATCGGCAAAGGTGGCAACAATATTAAAAAAGTGATGGAAGAAA CCGGATGCCATATCCACTTTCCAGATTCCAACAGGAATAACCAAGCAGAAAAAAGCAACC AGGTGGTTTGTCTTTTCACATGAACTTTTATGGGATGAATTACAGCCTTAATTTAATTTT CAGTTTGCCTATCTTTTTTTTCTGAGAGGTGAGACAAAAAAAAAATCACATAGATGACAT ACAGTGTAGATTGTACAACTTTCTGCAAGGAAATTGAAGGTGCTTTGCTTTTTTGAGGAG ATGAGTTGTAGATGGGCCCTAAACTCTTGATCTTGAAATCATTGATAAAAAATAGCGGAA GATGTAATGGCCACAAAACAAAACCTTAAAGAAAGGCTGAGAGAGCATATCGTTTAGGAC CTGGAAGCTTGCCTAGTCCAGGAACCTATCCATTGCCTGGTAGAGACCTGGAAGTAAATA CCTTTGTGGCACACCAGATCACCTTCTGAGGAGCAGTGCATTAGTGCCTGACTTCTTACA TTGCCTTAATTATGTCTCTCTCTAGTTTATACACATTTGTGCTTGTTCTTCTGTTTGGCA GCAAATGGAACTCACCTGTCCTCATGCAAGCGGTTTCAGTACTTGAAGAACAGATAGTAT TATTTGTGATATTTGGAAGTATTCTCTCTTCTAAACTAGTTACAATACTAGAAACTGTCA GCCACAAAGATGAATAGTCTTTTCTCTACAGGGACTAATGGTGACAGTGGGATGTGCACA TAAGGGACTAGACAGAAAGCTATAGTAAAAAGCAAAGACAATATTCAGAATATTTAAAAA CTGGTACGGCATGACCATTGGCCCTAAGAACAGTGTCCTGGAGCCCCTGTACCCCCCACC ACAATGCCAAGACTAACACCTTGAGTCAGTGGGTCATGGGAATGCCCAGGAGATTTCAGA AGTAAGCTCGAGGTAGATGTTGGAGCAATGATTGTGTACCATCTGGTATGGAAAATGTTC ACTATTTTCAGAACCTAGTGTAGCTCTGTCATTGAATATTGATAAGTATCTGGTATGCAA AGAGCTTAAACAAAACGGAGAAAATGCAGTGAACAAGAGTAATTATAAAGAGGGCAGGAT GATCTCCTGGGGGCTGTGGGGCTTTCAGTAAGTCCAGTGGGTGAAACAGATCAGTTGACA CAAATTACCTGAGGATCTCGTTAAAATGCAAATTCTGATTAAGCAGGTCTGGATGGGGGC CTGAGATCCTTTATTTTTAACAAGCTTCTGGATAATACCTCTGTATTTGTCCCTGGATGA CACTTTTAGTAGCAAGCATATAGATGAACTGGAAAAGAGATGTGAGTTTGATTAAAATAA ATCTAACTTTGTATTTTCCTCCTCTTATAGGTATCTATAGCGGGACAACCAGCAGGAGTA GAATCTGCCCGAGTTAGAATTCGGGTAACTATTTATTACTTTAACATTGTAAATTGATGT CAGCAACATTTGCATTATAAGGCACTAAAAATATAATAATTTATCATTTTATAACCGAAT CATGTTCAATCAGTAGGAAATAGTGGCAAAAGTTATTTTAGTGTCTATCTTAGCATTCAT TATCTAAATATTTATTGTATATGTTCAAAAAGTGAGTTTCTATGTTATTTATAAAATTTT TTCACTGAAAATGTTTCTCAGAGATGTTCTGGATTTTATCTGACTCAGTTTTTCTAGTTT TTATTCAATGATCATAAAGAGGCCTAAGGAAAAATGCCACAGGCAATGTGAGTTAGAAAC TCTCAGGTTTCACAAAAGGCTCCCATCATTTAAAAACACTTGTAGGCCAGTTGTGGTGGC TCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATCACTTGAGGCCTGGA GTTCGTGACCAGCCTGGACAACATAGCAAGACCCTGTCTGTCTCTACAAAACATTTTTAA AAATTAGCCAGGTATGGTGGCACATGCCTGTAGTGCCACTAATTCAGGAAGCCAAGGTGA GAGGATCCTTGAGCCCAGGAGGTGGAGGCTGTAGTGAGCTGGGATGATACCACTGCATGC CAGCCTGGGTGACGGAGCAAGACTCTGACTCAAAAAACAGAAAGGAAAAAAAAAAACTTT ATATAATGTAGCTAAACTTAATATCTATAAGGGCAGTTTATGCTTTAAAATCTATCTTCA GAAAAGAACCAATGAATGATACACATGTCTGAATGTCTAATGCTTTAACTCTCTGCTTTG GATTCTCATCATTTCATTTTAGGAGCTGCTTCCTTTGGTGCTGATGTTTGAGCTACCAAT TGCTGGAATTCTTCAACCGGTTCCTGATCCTAATTCCCCCTCTATTCAGCATATATCACA AACGTACAATATTTCAGTATCATTTAAACAGCGTTCCCGAATGTATGGTGCTACTGTCAT AGTACGAGGGTCTCAGAATAACACTAGTGCTGTGAAGGTAAATTATTCAGATAATTCTGC ACATCCTATATGTACAAGTTACATGAGTTTCATTTTTAAAGAATATTAGACTAATTTGAT TTCCAGAATTTTCCTTCGTTCTACATTTTGGTTTGCAGAATATGCTGTATTTTTCCATAG CTGTTAGAAATGCAATAGAATCTTTCCCCGTATATGAACAGTTAATGTATAGGATTATTT CTTTCCCACCCTTTTCTCTTAGGAAGGAACTGCCATGCTGTTAGAACATCTTGCTGGGAG CTTAGCATCAGCTATTCCTGTGAGCACACAACTAGATATTGCAGCTCAACATCATCTCTT TATGATGGGTCGAAATGGGAGCAACATCAAACATATCATGCAGAGAACAGGTGCTCAGAT CCACTTTCCTGATCCCAGTAATCCACAAAAGAAATCTACCGTCTACCTCCAGGGCACCAT TGAGTCTGTCTGTCTTGCAAGGCAATATCTCATGGTAAGGTTACTGAAATAAGTGTTACA ATTTTTTTAAACCTCTTTGGATTCAGTGCATGTTTTTCCATCCACTGTACTAATGTGATA TTTAGGAAAGCACTTCGGAAGCCTCGTCAAATAAGGAAGTTTCTTGCTAAAAGGAAATAA ACTGGAAGAGTAATAAGGTTCATAGTGCCTCAACAGGTTTAATTTCATTGCATATGTAAT TTTATTTCAGTGTTTTCTTTTTAACTTAGACTAAACACAGAAGAGAATTATAGTGAAATA ATTGACTGCATTTTGTGGCAAGGATGGAAGGTGACTGTTTTCATCTGACCTGTAATATTA GTGTGCAGTTTGTATTTGGCAAAAAAAAAAAAAGTCCTCTGTTTAAACAGAAAAGTAAAA ATACTATTTAAATTTCACCATCAAAGACAAATTTTGTCAGCCCAAAACATTTGTACATTT CATAAATCTTTGATCCAATTAAAAAATACTATTTAAGTCACAAATTCGAGCGTCACTTAT TGAAGGAAGAAAAGCAAAGTTATATATTATAATTCAATACTACTTTACTACTTCTAATTT ATAATTGCAATATTTCTATCCTTCCCATATTTGTTTAAAACCCCTCGGCCAGGTGCGGTA CCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACTTGAGGTCAA AATCAAGACCAGCCTGGCCAACATAGTGAAACCCCATTTCTACTAAAAATATAAAAATTA GCCAATGCGGTGGCAGGTGCCTGTAATCCCAGTTACTCAGGAGGCTGAGGGAGGAGAATT GCTTGAACCCAGAAAGCAGAGGTTGCAGTAAGCCCAGATGGCACCACTGCACTGCATTTC AAAAATGAAATAAATGAAATGGAATGAAATAAACTATCCCAGTGTATGGGTTGATAATGT AGTAACAAAATGGATGGACATGATGCTGGGCTTACAAATATTTGTATTAAAAACACCATT GTATTCTCTCATTCAGTGCTTGACCTTTAGTGGCATTTGAATCAGTAAGCCTCAGGTGTG ACATTTACTATTATTAACTTGCAGAGTTTATTTTTGAGAAACTTTCAGAAAATCTAAGTT TTTATTGTTGATTCCATTCCTCTGACAGACAAGAACTTGTTGGAATCAGTAAGATTGTAA TCCACGATTTTAAGAAATTTGTCATGATTTTTTTTAGCCGAGCTTATTTTATCAGGTTAT TTTTAATATACTGTACTACAAGTCAGATTTATATTTATATCCAAGAATTGTTGTAATCTT CATTTTTTTTCTGCTTTACAAGTTCTTTAGATGTTATTTTTTAGTTTAGTGAAATTTTTC AAATATTCTCTACAGTTATTAATGCACATTTATACTTTGACCATACCTGCCAAAAATAAT GACTCATATTATTGCACAACATTGAAATAACTGAAGGAGAAATTAAAAGGCTTTAACCCG TATTTTAAATACCATCACCATTTTGTATAGCACTATTCTTATAAAAATCACTTCCTGGCT GGGCGCGGTGGCTTACACCTGTAATCCCAACACTTTGGGAGGCCGAGGCAGGCGTATCAC AAGGTCAGGAGTTCAAGACCAGCCTGGCCAATATGGTGAAACCCCATCTCTACTAAAAAT ACACAGAAAAGTTAGCCGGGCATAGTGGTGAAGGTCTGTAATCCCAGCTACTCAAGAGGC TGAGACAGGAGAATTGCTCAAACCGCGGAGGTGGAGGTTGCGGTGAGCCGAGATCGCGCC ACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGTTTAAAAAAAAAAATCAATTTCTT CCACAGGAGAAATGGAGCATAGTATTTTATTTCTTTTTCTTTTTTTAGTTTAGGTGAGGT CTTACTCTGTTGCTCAGGCTGGAGTGTAGTAGTGTGTTCTCAGCTCACTGCAATCTCTGC CTCCTGGGTTGAAGTGATTCTCATGCCTCAGCCTCCCGAGTAGCTGAGATTACAGTCATA TGCCACCATGCCTGGCTAATTTTTTTAGTTTTAGTAGAGATGGGGTTTCACTATGTTGGC CAGGCTGATCTTGCACTCTTGGCCTCAAGTGATCCACCCACCTAAGCCTCCCAAAGTGCT GGGATTACAGGCATGAGCCATGGTTCCCGGCTTAGTAATTCATTTTAATCCTAGTGTGCT TAATGGTAACCTCTCCTGATATCCATTTACAAATTCCAGCACCCAGTGGGCTAACACTGG AAATTCTGTGCATCAGAGAAAGTATATTACATTGTTCCTAGACTCAGTAGATCAGAGGCT GTGAGTAGAGCATTAGAGAAAAAAAAAAAATCTAAAAAATGAGGTAGTTAAAAGAAGGGA CAGTAGTAACAATTTACTCCAGGAAGGAGGAAAGGTTTAAACTGCATTAGGTTAAGTAGG ATTTATATTGGTGAAGAAGCTTTTGATGAGTTAAGGCAGGGGTCCTCAATCCCCGGGACA AGGACCGGACCAATACTGGTCAGTGGTCTGTTAGGAACTAGGCCACACAGCAGGAGGAAA GCAAGGGAAGCTTCATCTGTATTAACAGAGGCTTCCCATCACTCACATGACCGCCTGAGC TCCACCTCCTGTGAGATTAGCAGTGGCATAAGATTCTCATAGGGGCATGAACCCTATTGT GAACCGTGCATGCAAGAGATTTAGGTTGCATGCTCCTTAGGAGAATCTAATGCCTGATGA TCTGTCACTGTCTCCCATCACCTCCAGATGGGACCGTCTAGTTGCAGGAAAACAAGCTCA GGGCTCCCACTGATTTTACATTATGGTGAGTTGTATAATTATTTAATTATATATTACAAT GTGATAATAATAGTAATAAAGTGCCGAATAAATGTAATGTGCTTGAATCATCTGAAACCA TCCCCCTTCCCTCCCCCTCCCCTGGTCCATGAAAAAATTGTCTTCTGTGAAACTGGTCTG TGGTACCAGAAAGGTTGGGGACCCCTGAGTTAAGATACCAAAGTACAAGATCCTCTTAAA GGATCGTTGGGAGGCTGGCCTAACCTGGAGGAAGGGGAAGACATACAGATATAAATCTGT GGTTGAACAAGCAAGTCTGGGCTAAAATGTGGAACTCTTTAAATGCTCGATCATGTTTAG TTTTCATTCAAAATACAATCAAAAGCTGCCACTGGAAGTCATTGAGCAAAGGCAAAGATT AGTACCCTTGATATAGTCGAGAATCTAGTTTCTAGCATAACTTAACAAAACTGAAGTTAG AGAATAAAGGAATTTTCCAAGGTGCACAGTGGATAAAAAAAGTCCGGGGCCAAAAACAGA AACTTAAGACATATAATTTCGTCATCCAAAAATGGTTTTCTCCCCCTCAACGTTAATGCC ACACCTGTCCTCTAAGCTATGTGAACTTATATAATTCAGCTTTAATACTTCAGTTTAGTC TTTAAATCTGTAAAATAGTGCATTATTTGCAGGCATGTTAAATTATCAGGTGTTTAAATG ATTAAATTTTTACCTCCTACACATTCTATTGTGACATTTTCTAGGGTTGTCTTCCTCTTG TGTTGATGTTTGATATGAAGGAAGAAATTGAAGTAGATCCACAATTCATTGCGCAGTTGA TGGAACAGCTTGATGTCTTCATCAGTATTAAACCAAAGCCCAAACAGCCAAGCAAGGTTG GTTCAGAGTCTGAATCCAGAGAATTATGTATCATATCATATGCTGTATAGTTTTATTTTG CATAGAAGTATTTATTTGCATATACATGAAACTGTTACTCTATACAGGTTGAATATCCCC AATCCGGAATGCTCCAAAAGCTGAATCTTTTTTAGCACTGACATGACAGTCAAAGGAAAT GCTCATTGGAGCATTTTAGATTTTGGATTTTCATATTAGGGATGCCCAACCAGTGCAGAT ATTCCCAAATCCCCCAAAACCCCAAATCTAAAACACTTCTGGTCCCAGGCATTTCAGATA AGGGAAACTCAACTTGTATAATATATATGTCATTATATATTTAGTTATCTAATATAAATT TGTAACAGTATTCATTATAGATCATCATTTTCTTTATATATGTGTTGGTTTTTGCAGTCC ATTTAGAGTAACCATTATTTTTCCATAGTTAAATGAGAAGGAAAGAACATTTGTTCTTAA TTTAGAATCTGGTAACTTGAAGCTTTTCTAAGTTACCCAAGAGTTGATAAGGCTACTTAC ATGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACATGCCCA GTGTAATTCAGAAATTGTTTAGACTACTTACTATATGCCATCTCCTGCGCAAGCTGGAGA GTTAAAGAAGAGGTGCCTGTGCTTTTTTGTAAATACTTTAAGGACTGAACTGTCTCAAGT TCAGCGTTCTTGGAATCTCTCCTCAGAGTGTTGTAAAATTTCAGTAACTACATGTAGAGT AAAAATTTAATGGAATAAATGTTTTTTTTTTTTTTCTGAGACAGGGTCTCACTTTATCAC CAAGGCTGGAGTACAGTGGTGTGATCGTGGCTTACTGCAGCCTCGACTTCCTGAGCTCAG GTGGTTCTCCCACCTCAGCCTCCCGAGTAGCTGGGACCACAGGCATGTGCCACCACACCT GGCTAATGTTTTGTACTTTTTGTAGAAATGGGGTTTGGCCATGTTGCCCAGGCTGGTCTT GAACTCCTGCGCTCAAGCAATCCACCCACCACAGCCTCCCAAAGTGCTGGGATTACAGGT GTGAGTCACTGTCTCCGGCTCAGAATAAATCTTTTATTAAGTGCTAGTAAGAATGAGGAA AGAGGAATGTTTCTACATTAGTATTGTTGTTTAAACTAGCACAGCCACTTTGAAGAGCGA TTTCTGATCATCGCATTATTCTAAGATATTGATTACCCTACCTGCAGTAGTTCTACTTCT GATTATACACTCTGAAAACACCTTTGCACCAAGAGACAACACGAGAATGGTGTTGAGTAA AAAAAGTATATTGCATCGTAGTATGTAGTCAATGGCAGCATTTTTGTGTATATATATGTC TGTACATTTTTAAGTATAAAGCATTGTTTAGAAGGATGCACACAAAAATCATGATGAGTT GCCTTTGGGGCAATAGAAAGGAAAATGGAACAAAGTAAACAAGGGAGATGTTCTATTTAT TTAACAAAAATCCGAAATAAGAAAATAACACCATTTTTAAATTTTGAAACTATAAATCTT ATATGCATAGAATGGTGTATATATAATATGTATTTTATATAATTTGGTATATGTAAATAA TGTGGTAATCGCTGTCCAACTGAAGAAAAATGATCTTGCCTTCTCCCAAAGAAAACTTTA AAGGAAAAGATAGCATTGATTCTAAGTGAACTTGATATAATTAGTTTAAAGTTAGGGAAC AGGACATTAATTTTATGTATCGTGAAGCTTCATGTGTGACTAATTTGAGTTGACCAGAGT CACTGTAGATACCAGGACTAAAAGATAAAGACAGGAGAGACATTAGAGGGCTTGTGCATA TTAAGATGGACAGTCAGAAGAATTCCAGGAGTTCAGTAAGAAATGAGCAGAAGTCAGGGA AAAATAGATTGTAAATGAGAACTCCAGAGCCTTGCAGCATCCCAGGGCCATTTAATTATG CCCAGCTGGCCCACATTCTAACTACTGCTTTAACTGCTTTCTCAGCCACAATTTTTTTTT TTTTTGGTCCATTGAGGGCTTTCCCCTTTGAGTTCACATTTCAAATTTTCTTGATGAGTC CATTGTGAAAGAAAAATGATTTATTATTTAGAATTTTTTTTACCATAAGCTTTGCCATAG ATATGTCACCAATGAGGGATAGTCATACCTCAAGGTCTATTAGCTAACTAGTAAACCATA AATGTCAAACATAAGTGATGATGATGATGCAGTTTATATGTGGTCACAAGTTTGATTTGG TATGTAATGACAAGATGCAAGGGGGAAGCTTTAGTGTAAAGATGAGGGGCTGTAAAAAGG GAACCCAGGTTCCCATCCTCTTGCTGTCTCTTCACAGCTGTGCCTTGACCTGGGCTAAGT CCCTTAACTTCACTGAATATGAGTAATGATTCCCACCCTATAAGGTTTTGCTGAGAATAG GAACATATATGCAGCTACTATCACAGCTCCTGGAACCCAGAACATGCCCAATAAATGGTA ACCAATAATTTAGGGTTTTGCCAGAAGGAGTAATCTTAAGCACGAAGTGGTTAGAATTTG CAGATGATTTAAAAGCAGCATTGATATGTCCCCTGAGTGGAATTCTTATTAGCGTATTCA TTTTCCACCTCCCTCCCCTCCCCCATTCATTGTAGACTACTTGCATGTCACCTTTTTTCC CCCATTATGTGTTTTCATAGTCTGTGATTGTGAAAAGTGTTGAGCGAAATGCCTTAAATA TGTATGAAGCAAGGAAATGTCTCCTCGGACTTGAAAGCAGTGGGGTTACCATAGCAACCA GTCCATCCCCAGCATCCTGCCCTGCCGGCCTGGCATGTCCCAGCCTGGATATCTTAGCTT CAGCAGGCCTTGGACTCACTGGACTAGGTATACAATTTATTATTACAGCGCGTCTCAGTC ACTGGGGAAATGCTTGTCTGGTTCCCTTTCTTTCTACCATTCGGGTCTACATTTAAAGGC TATTTTTTTTTCCTTTGGGCTCTAAGATCAGATGAAAAGCCATACAACCTGAATCAATCC ATTTTGGGGTTTCTTAGTCTCTGTGGATTTGTTACCCAGATTCTTCCCATGTTTGCATAA ATAATCAAGGTCTGACTATTTTATTTTCGGTGGCTGTGTTTGTTCTAAATTAAGAATGCC ATTGAGATTGAAGTAAGCATGCTGACTGTAATTTATGTTTGTTCTCTCCTGCATTTGCAA TATTGTCTTCAGTCCCTAGAGATAAAGATTATCCAGTTTGCTTTTTAAAAAGTAATTGCA AATCTGTATGAGGGGTGGGGAGGGGGGTGAAAATAAGCAGAACCCGCATCTCCAGTGGTT AGGCCTGCCTTGCCTAGATACAAAGGAAATCTAGTCAGAGGCCAGACCTGTATTTCTGTC TAACGTGAGGAATAGAAAATAGAAGAATGAACAAACGTCATCATCTCAGAGCTTCAGTCG AGAAAGTAGAATGAGCTGTTTAATAGTCATGGTGATATTTATGTCCTCATCTATGGATTG CTATTTTATAGGCTGAAGTTAATTGCTGTATTACAGTTTTGCTAGATTTATTTCTTTCCT GCACATTTCTCAGTTGCATTTATTTTCCTTAATCAGTACTCCTAGAAAATCATCCTGGGT CATTCAGTGTTGATTTGAGACAAAAAAGAATACTCTCAGCAGTCTTTAAAATTTTTTTTC CAATAGCTATTCTTGCAGTCTTTAAAATTTTTTTTCCAATAGCTATTCTTGCTTTTAACT TTTAAGAAGTTTAATGCTCTTATATGATTGATTTTCCAAGTAGCCCTGCCTAGACATCAT TAAAGAAAGATTTTTTTTGTATCTTGGCCCCTAATCTACCAAAGTTGTTCCTTCCACTGG GACCTGAACAGAGTCATAACAACATAGCAATGACTGTGAGTCAGGAAATGCCAATTAGGT AACTTAGCAGGAACCTAGTTCATCCTGCACTACAGAGAAAACAAGTGAGCAAAGATTCAC TAACTGAATTTTTAAAATGTTTTCATTGCTATACCTATCCTGTTATATACTTTATGCTTT ATATGTATTCCTGGAAACTTGTATACAAATCCACATTTCATTCTAGAACATATTTTAAAT GCCCAAAGGAAAATTTCATTATTTAAATCAAGCATTGACTCCTTAGAACAACAACAACAA CAACCAAAAAAAAACAGTATTTTTTTCTGAGGAAATTTTCATCATTGAGATGGAGCCCAG GGAAGTCATGTATATGTTTTGAGATACATTTAGGAACTGTTCTGGTAGCCTACCCTATCT GCAGCGGGGACAAATAGATCTATCCTACCACAGGAAAGCATTCCCTAGTCGCTGCTACAT GTGAGTAGTTTGAAAAGGGTTTGTTTGTAAGCAGATGACAAATGAGTTATGCAGAAGAAT AAAAATGAGTTTCCACTTGAGCAGAATTTTGTTCATCCTGGGTAGCTGACATGAATGCAA GCACCTGGTGATGTTCAATGACCCTAACTGCCATCCTGGTCTGGGCACACCTATCTTCCA TTTTCTGATAGCAACTCTTTGTGGATAAGCTGCTTCCTCTGTTGGAGCTGTATGATGCAA AACTCATGTGAGTATTTGAAAGAAAATCTGTCATCCATATTTTATATTTAGAAAATATCA GATTATATCATTGTGCATTCCCAATGGCAATATTGGTGCCATCTCTATTTTAAAATCTTA AATTTATGTGAATTGACTTTATATATTCATTTATTACAGGTCTTTTGGGACCCACCACCT TATCTCTGAACACTTCAACAACCCCAAACTCACTCTTGAATGCTCTTAATAGCTCAGTCA GTCCTTTGCAAAGTCCAAGTTCTGGTACACCCAGCCCCACATTATGGGCACCCCCACTTG CTAATACTTCAAGTGCCACAGGTCAGTATCATTTAAGTATATTCCAAGTTGTGTATTCTT AGGTGTTACCAGTTTTTTAAATAAAATTTACGAAGGGCTCAGTTTTCTTAAGGCAAAATT AGGGTTCAAAGCATACTCCATTGAAACAGAAATTCCCTGATATGTAAATTAGTTAAAATG AAGAACAGCAAAGCAGTTTGAGTTTTTCATACAACTGAAATACCATCTTCAAATGTGATA AACAGACCTGGTAGTTAGGTTCTAGTTGGAGTAACTTGCTGGTAGTCATTTACATCTGTA CAATGAGAGGGTTGGATTAAATATTCTCTATGATATTGTCCGATTTTAACACTCTTTTGT GTTTTTATAGTAAATAGTACCTCTGTTTACAGAGGTGTCAAAATTGAATTCTTTTCTGAA CTTGCAGCAACAAAAATGATATTTTTATTGTTAATAAAAATAATAGTTGAATCTGAGTTT CTTCCTAATATCTGTCATCATAAAATGTTGTTGTAGGTTTTTCTGCTATACCACACCTTA TGATTCCATCTACTGCCCAAGCCACATTAACTAATATTTTGTTGTCTGGAGTGCCCACCT ATGGGCACACAGCTCCATCTCCCCCTCCTGGCTTGACTCCTGTTGATGTCCATATCAACA GTATGCAGACCGAAGGCAAAAAAATCTCTGCTGCTTTAAATGGACATGCACAGGTAATGG CCTTCTGCCAGAATGTGTGTGTGATCTGTACTGTTTGTAAGAGACAAACCCCTGGTAAAG TTAAAACATGCTAGAATGTGTGTGTGTGATCTCTGCTGTTTGTAAGAGATAAACCCCTGG TAAAGTTAAAACATGTTTAAACTTTCACCTAAAATGAATTTTATTTATTTTTTTCAACTT TTATTTTAGGTTTAGGGGGCACATATGCAGGTTTGTTACATGGGGAAATTGCATATTTAA CCAATCTTGAGTTAATTTTTATATATGGTGAAAGGTAGGGGTCTGGTTTCATTCTTCTGT ATATGGCTAGCCAGTTTTCCCAGCGCCAGTTATTGAACATGGATTCCTTTCCGTATTGCT TGTTATTGTCGACTCTATTGAAGATCAGATGGTTGTAGGTGTGCAGCTTTATTTCTGGAT TCTCTATTCCGTTCCCTTGGTCTATATTTCTATTTTTTTTTTATGCCAGTACCATGCTGT TTGGTTTCTGTAGCCTCGTAGTATAGTTTGAAGTCAGGTAGTATGATGCCTCTAGCTTTA TTCTTTTTGCTTAAGATTGCTTTGGCTATTTGGGCTCTTGTTTAGTTCCATATGAGTTTT AGAATAGTTTTTTCTATTTCTGGGAAAAATTATGTTTGTAGTGTGATAGGAATAGCATTG AATCTGTATATTACTTTGGGCAGTATGGCCAGTTTAATGATATTGATTCTCCTGATCCCT GAGAATGGGATGTTTTTCCATTTGTTTGTATCACCTACAATTTCTTTCAGCAGTGTTTTG TAGTTCTCCTTGTAGATATATTTCATCTCCTTAGTTAGAAGTATTCCAGGGTGGTTTTCT TTTTCGTGGCTGTTATAAATGGGATTGTGTTCTTGATTTGACTCTCTGTAAAATTGTGAC CATATTTATACATTATTTTCTATTATTATTTTAGTCTCCAGATATAAAATATGGTGCAAT ATCCACTTCATCACTTGGAGAAAAAGTGCTGAGTGCAAATCACGGGGATCCGTCCATCCA GACAAGTGGGTCTGAGCAGACATCTCCCAAATCAAGCCCCACTGAAGGTCGGGAACTGTA CCCTTCTGAAATTCATTTTGGTTGTTATTTGGAAAAAGGAGGTTGTAGAGAGTCTATGCA GTGATTTTTGAGTTGGTTTTGCTAAACAGCTATCATTCATCCTACCTCAATTATGTGGAA AGACAACATCCTGAATAAAATTTCAAAGAGCATGGTGAAAGATTAACTGAAAAGCACTTT CCACAGAAATAATCATTTCCCCATTACATTGTAAGTTCCTGAATTAAAGTGAAGGTAATT GTGCAGCAGAAAAGCATCAACTTACTAAATGTTATATATATAGTTCCCCCAAGTAGAGTA TCTTTTTATAACCTTTTTACCCACCCCCTGCCCCACCAAATCTTTAAAATATATGCGGGT CTTCTCTTCAAATTGAGTTTTTGTGACAACCTGAACTTGTTAAGGTGTTTCTTTGCAGAT GGAAGAGGTCTCTGTCAGGTTAATCATGTCTCCATAGAGTAGGGTTCTGATTTGTTTCCA TTGCAGATAATTGTCAACTGGAAGGTGATGTTGTTTAGGTGTTTCACTTTTTTTTCCTTT TCCTCTGCAGGTTGTAATGATGCTTTTGTTGAAGTAGGCATGCCTCGAAGTCCTTCCCAT TCTGGGAATGCTGGTGACTTGAAACAGATGATGTGTCCCTCCAAGGTTTCCTGTGCCAAA AGGCAGACAGTGGAACTATTGCAAGGCACGAAAAACTCACACTTACAGTATGTATTTTAA TCTTTAAAGAGCCCTTGATATTTTGAAATGATATATATTTGTTCTCAACTCTATAGTTAG TACTCTTTGATTCAAGTCATGTTTGATCTCATCCATGGGTGTTTTCATTTTAACTTTTTT AAAAAAAATATTAAGGAATAATATCTGTTAATTTTCACCCTTCTCTGTCTTCTCTATAGT CCCTTCCCCATTTAATGAATTGATTTATATCTGTGTCCTCTAAACCGTCTGTATTACTCT GAAACTGTAGCATTCTCTCTGCTCTTCAGTAATCAGCAGGGCCATTTTTATTCTCTGATT TTTGCTGTTAGAAATTTTCCCACTGTGAATTCTCCTTCATTTGGCTTTGAATTTCTTTCT TACTGTGGCTCTCTTTTTTCCCAAGGTAGTTAATTGCAAACTTTTAAATAAATGCTTGAC ATTATCATGACTTTGTTTATTCCAAATCACTTTGGTTATAAATACATAAGTTGTATTAAA TATTAAATATAACTCTTCCTTACCATAGCACAGTTAAAGTATGTCATCCTTACTCTTTTT TTTTTTCCTCCATGTATTTTGGACAGTCTCTACAATGTAAGGTTTTGTTCCCACCTATTC CGTCCACCTGATTTCCTCTGCTGTCTTATTAGTTCCTGGTATACCCTTCTAGAGTGTCTT TATGCAAAGATTAGCGTACATGGTTTTATTTCCTCCCATTCTTATTAAAATCCATTTTCC TTTATAAACTCTTTGGTCAATCATTATTACCCACCGTTGTCCAGTTCTCCTTTATCTGTG TTTTTCTTTACATGGAGCTAATACCCAAAATTAATGTTCTCATTATAGGCTAGAGAAACA GTTTTACTTCCTTGAAACTATTGAAGCATTTAAAATAGATACGTATTCTTGTCATCACTG AGTATGTCCTGAACCTTCTTATCATCATCTTTTGGCTTAAGCTGCAGCCTCCAGAAAGGT CTCCCTGCCTCCAGTCTTTTATTAGCTTGATCTATCCTTTATTTTGCTTCAGCAATTTAC TTTCGAAAACAGGTCTAATCTTGTCACACTCTGGCTTCAAATCACCAATGGTCTGTGTTG CCTGCTTCCTTTCCTTTACTTATGCTCTTCCCTCTGAGTTGCTGTTCTCCTGACCTTTGG CACCAGACAACTTGCAGATGCTCTTAAGTTCCCAGGTCAAATGTCCTTTGTGTAGCCTCT GTCAACTTTTGTCAAGCAAAGTTCATTGTCCCTCTTTTTGTATTCCCCAAGTACTTTTCT AAATTCCTCTAAATTCCCTTGGCACAGCAGCTGAGTAGTTGAACAAATAAAATCATGAAT GAATAAACAAAACAGTACTTGATTGATATTGCAATCCCTATTTTGAGCCTAAGGTGCAGT TAGATTTGAACTTGTGGTGCATGCATTCTGTACATATCATGTGTTGTAATTCACATATTT GCTGCTCTAAGAAGCACTTTTACGCTCTGCCTGTCCCCCTCAACAGACTTTGAAGAATAT TTCTTATTTATCTGCTACATTTTATTTGTTACCATCATATACATATTTCATACACACGAA TTGGATCATCTACATCCCTTCAAATTGACTGGATCTCTGTTTGGACTTTGCATGGATGAA TCATTGATATCTCCTTGATGTATAAAAATTAGAAATCTCATCTGTACATCTATTCCACCT ATATCATATGCAGTATACCATATATACTATATATACTGTGTTTGAATGTGCATCATGAAA TAGTTTCAAGCTTTAGCCCTACAGTCAGAGTGCCCAATTTCAAATTCCATCTCTACCATT CACATTAGAGGTATGACCTTGGACAATATACTTCCTTCATCCACAAAGTGGGGATAACAG TAGTACCTGTGTCATAGCATTGTTGTGAGGATTAAATGAGAGACTACGTGTAAATAGCTG ATGATGATAAACATGCATAGTAAATGTGGCATGTAGGAAACATTCAGTACATTTGTATAT ATAGTGGAGTGTTAAATTCCACACTCTTATTTCACAGCAGCACTGACAGGTTGCTCTCAG ACCCTGAACTGAGTGCTACCGAAAGCCCTTTGGCTGACAAGAAGGCTCCAGGGAGTGAGC GCGCTGCAGAGAGGGCAGCAGCTGCCCAGCAAAACTCCGAAAGGGCCCACCTTGCTCCAC GGTCATCATATGTCAACATGCAGGTAATGGTAATAAAATAGGAAAGCCACTCAAATGTCA TATGTTTGGGTTCTGGTATGGAGAATTCAGTGAGTGTTCAGCAGTAGTGCAGAAATTAGG TTTTCCTTCTGTGCTACATTCAAAATGAAATTTAAATATATATGTAGCAGTTAGTTTGCT ATAAACATTAAAAATGAAAAGCAGTATTTACCTTAAGTGAGAATTCTTTAAAATATATTA AAAATGGTGCAGAATGGTCTGTGTCACTGTCTTATGCAAATAACATTATTCATGTGTTAC TTAAAAAATTTTCAGATGAGTTTGCGGGACTGCATTTCTAAGTATTCTTGCTTCATGACA TAGTCTTGGATAAATAGATATACTATTTTCTATGTAATGAAGATGATGAATGTGTTTGGT GCCATTTAAAGATAGTTATGAGAATAACGAATGTGGAGTGTTCTTTGAAACTAGATGATG AATATTATTGATGATTGTGTTGGTTCACAGATTTTTTATGATTATAAAAACAACTTCCTT TAAATAATTTTTATGATTAAACAACTTCCTCAATAGGAACTTTCTGTGTTTCCATTTTCA AACTATTAGTCTAATTACTCAGAATAGACTATTGACCATGAAAATGCAGAAATTATAGAT GACAATATGAAAGATAAGGATTTGTGCTTTGTGCTTTTAGAGATGCCTACAAGCATTTGA TGTCAGACCAGAATTGCTGAGTAGACTTACCTGTTTTATCTTTCACCACCAAAAAAGAGG AAGAACGTTCCACAAAATCCTAGAAACAGAAAAGCTGTCATAGATGTGTCAAAGAAATTA ATTCATGGAGCTAAACTATATTACTTTAATTCCAGTGCAATCTGCAGTTTAGTCCTCCTT CTCTATTTTTTTAATCCTTTGCATTGGAACATTTTCCTAAGTTTTTCGATGAATTTTTTT TTAAATAAAAGCTATGGCCTTTATAATGTGTCAGTGTTTAAAAAAGACATTTAAGGCCGG GCACAGTGGCTCACACCTATATTCTCAGCACTTTCAGAGGCCGAGGCAGGTGGATTGCTT GAGTCCTGGAGTTTGAGACCAGCCTGGACAACGTGGCAAAACCCCATCTCTACAGAATAA TTCTAAAAAATTAGCAGGGCGTGGTGGCATGCACCTGTAGTCCCAGCTACTTGGAGGCCG AGGTGGGAGGATCACCTGAGCCTGGGAGGCAGAGGTTGCTGTGAGCCAAGATTGCACCAC TGCACTCTAGCCTGGGAGAGAGAGCGAGACCCTGTCTCAAAAATTAAAAATAAATAAAAT AAAAAAGACATTTATTACATTTTCTCTGGTGGATGTATTTTCAGTTAATATGAATTACAA TTTATTTAACAAATATCAAATCCCCTTTATAATCTTTTGATGGTTTTTGTCTTGTGGTTC TTGTCACCTTTTCCATCAGATTTATACCTGCAGTGAACCAGTTTCTTGTTTCTTTCTTTT AGGATGGATGAGCATGTTCTTAATGTTTGAGTTTCAGCCTAACTCGATGTATTTATGTTG TTAGTGAACAGTTGACTCTTAATAAATCACTAAGAAATCAATGATAATATTCACTGAGCA TTGACAGGGAGAAAGATTGAAAACTTGGCCTGATTTCCTTGGCTGAAAATGATCTGTATC TCCTGATTGCTCTTGGAGTGCTATATCCCCAGCTCTCTTTTTATGCTTATCTCAGTTTCT AATTTATTTTATAGTTATTTCTTTTTCCCAACCCTCCTAAGACTGCAAGTCAGCCAGGCA TGGTGGCTCACACCTGTAATCCCAGAACTTTGGGAAGCCAGGGTGGGCAGATCACCTGAG GTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAACCCTGTCACTACTAAAAATACA AAAATTAGCCCAGCTTGGTGGTGGGCGCCTGTAGTCTCAGCTACTTGGGAGGCCGAGATA GAAGAATCACTTGAACCCAAGAGGTGGAGGTTGCAGTGACCTGAGATTGCACCACTGCAC TCCAGCCTGGGCAACAGAGCGAGACTCTGTCTAAAAAACAAACAAACAAACAAACAAAAA AACTGCAAGTCATCGAGGCTGTAGCTTATTTTTGATTAGTTGTTGTATTCTTCCACAAAG CTGAGCATAGTCTCTTTAACCAGTAGGCCCTCAATGAATATTTGTTGAACAAGTAAATTT AGGTTCTCCGTATACCTTGCCTTTAGGCATTAATAATTAAAAATTGATTTTAACTCCCAA TGCCATTTTAGTCCTAGGATTTAAAAACTTCATCAAAAATATTATCTAAAAATCTGGCTT TCCTGACACATGGCTATGTTTTTAGTTATCACATGTCCTTGTTTGTCTGGGACAGCCTCT ATTTACTTTTATTATCTTGGCCTAATTGTTATTCACAGCACATTTCACCTTCAGAAATGT CCTGTTTCAGACCACAGATTATATAGGTACCTTATATATGATGGTATAGTCTTTCTGGTT AAAGAGCTCTTGCCAATTGGCCCTTGGTCCTTGTGGTAGGCCTTTGAGACATGCTTAGAT CAAGTCTTAGCTATTTCCTAAATTGGGGAGTTGATAACACTCAGAAAAGATTTGAAATGT AGCTGTATCTGCACTACTTTCTTCAAAATGATCTATCTTAGTCCTCACATACACTTGACT ACATCGTAGTTACTCATTCAGTTTTAATGGAATGAATCAATGGTGCTATCCTAGCCCTGT GCAATAAACAGTAACTAGGTTTAATTTTATGGCATTGCTTAATGTCATTATAAATTAAAG TTAGACATCTGCCATTTATCTCACATCTCACTTCAAAAGCAAAGACTATGCCAGTTAGGT TAAATAATTTCTTAAGGTATCTTGACATCATACCACTTCAGGCCACGCTTACCTAAATGA AGAGGGGATTTTTGAGACCCTAAGGGGGCCAATAGATACATGACAGCATTTTGGAAATGT ATACTTTCAAAACCCACATTATTATTATTAGGCTGTTCACTATATTCTAGCAGACATTGG CTCTGGTGTGCTAGGTATTTATGGTAAATAAGATTTTTTTTTCTTTTTTTAAGGAAAAAT TCTAACTCTTAAAGTCAACCTTAAAGTCAGAAGTGGTGATTTATTATTACTAATTAATTA GTGTTGGAAACATGTTTAAACTTACAGACATACCTTGGATTTCTGTGGCATTATTGTGCA AAGCTTGGTGTATGTCTCAGGCAGATTCATGGAACACAGTCAAAACCTTTGTTCTCTAAC CATGGAGTGTTGGCATGACATTTGGAGAGACTGTCAATAAAGGTATTTTCTGTTTCATTT TCAGGCATTTGACTATGAACAGAAGAAGCTATTAGCCACCAAAGGTATGTAATACACTAA TAACTTACACTTGACTATATTTTAGTACACTCATAAATGTTTTTTGAGTACTCATGGTGA ATCGAGAACTTGAAAACTCAGAAAAAGAAACCTAGAATATTTGGGTTCAAGTTGCATACA TTCTGTTGAATATATTTTGTTGAATGGTTTAGCATTAGACCAATTAAGAAATCATTTAGC ATTTTTTCATTTATCATTACTTGGATAAAATATTTCATTAAGATATTTTTAGACATTTTG TGTTAAGAAATAACATTCAGTGATAATTTCTTCACATATATCAAAGAAACGACACTTATC ATCAGTATTTTATTGAAGAAATGCATTAAACATACCAAGCATTGGTTTTATTTTGTTTCC AAAGCTATGTTAAAGAAACCAGTGGTGACGGAGGTCAGAACGCCCACAAATACCTGGAGT GGCCTGGGTTTTTCTAAATCCATGCCAGCTGAAACTATCAAGGAGTTGAGAAGGGCCAAT CATGTGTCCTATAAGCCCACAATGACAACCACTTATGAGGTTTGTAGAGTCATGTCCTAC TCATTCTTCCTGTCTGTTCTTTCAGCAAAAGAGGACAGTCCTTCCCCCACCCTCATTCTT TATGTACCTAAGGGAAAATGATTAGTGGTGACTTGTTTTTATTTCTATTCTTGTAAACAC ACTGTTATAAAACTGATGCACTCTTGTGTATTATGATCTTTTATCTGTATTCTCTCAAAG TTGTTGGTCAGCTCTTAAAGAGATGTAAATTTGGATGTGAGTTTTTGTTGAGTGTGGGAT GTGTCATAAATGATAAGCGTAGGGCTGAGATTAAGCAAAAGGGAGATGTAATATTTCATA AAAATGTCTAAAGAGTCCTATTATCCAAGGGTTTCACTAGCAAGGTCACGATGGGGGAAA AGGCAAATATTCAACAAAAATAGGTTTTCAGATATGAGTTAAAAATTCAGTGTGCTCAGA TGTGCCAAGAACACAGCAAGAAGTATCTGAAACAAGTGCTCCAAAATTTTTATGTTTCCC AGATGTTGGCTGCCCTGCTCAGGGTGAGACTGGGAAGCTGGCATTCCTACCATATGGAAG GGATGGAGAGTTCCATACTCCACAGCCAGGCTACACGCGATTCACCAAGCAGGCCTTTTC CATTTCAAAGTATCAGATTTTGGCTCTAAGCCTTTGGGAGTCGGGGTGGGTCTAGAGAGA GCGTGCACACATACACAATGCTGGGAGACTGTACACACCCAAACATGGATGAAAATGATT AATCCAGGAGTCACAGTGTTCAACCAGAGAGAGCACTGTAGGCCAAAAAACAAACACTGG TTAAGGGTTTCATAATTGTTAGTCTAATAACTAGCATTTGTAGATTGACCTTTTCTCCAC CCATTTGCTTTGTAATAAATTAGGCTATTGATGAAACACAAAAGCAAACATGCTGCTTTT TTTTTTTTTGTCTCTTTTGAGTAAGTGAAAAAGAAAATACTATTGAAATACTAAAAGAGT CTCCTGTGAATTTCATTTTGGGAGTTATAGTAGCAACATGGCAGGCTGTGTTTTAAAGAT TGAAGTTACCTTCAGCAGCAGAATGTAGGAACCATTATGAAAAATGTTGAGGCTCTAGGA GGTACACTCTTCTTTCTTCCATTATAACACAGAGAGAAAATAAACATCTCCTTTTGTTAA CAGAGACCATAAAACTGCTGTGCTCATTCTTAGAGTTTCACCTGATGTACGGTATGGCTA TTCCTTTCAGCCCATCCTTGCTTTTGACGGAGTGAAGTGTGCCAGATTGTTGACTGTGTT CCTATAGTTTCAAAGATGAAGTATTTGCTTTAGAAATGCTCATTCAGTTCTGCTTTCTAA GACCAACAGTAGGACAAGTTGAAAATGATGTTCATTTCGGTAATGGAGTGGTCAAGTTCA GGGTTCTGATAACCACCTCTGACCAGATGTATAGCTTTGGTGAGGGACTTCACTCATCTG AGCTGTGTCTCATTCAGGTTGTGCTGAGAAGGGCATTGGAGAGGGCATCCAGTGATTAGC ATGATGTGTTGTCAGTTCTTAGTGATATTTAAAAAAAATTTTTTTTTTTTTTTGACGTGG AGTCTCACTCAACCCCCCTAAGCTGCAGTGCAGTGGCACGATCTCGGCTCACGGCAACCA CCATCTCCTGGGTTCAGGCAATTCTCCCATCTCAGCCTCCCGAGTAGCTGGGATTACAGA CACCCACCATCATGCCCAGCTAATTTTTGTATTTGAGTAGAGACAGAGTTTCACCATGTT GACCAGGCTGGTCTTGAGCTCCTGACCTCAGGTGATCTGCCCACCTCGACCTCCCAAAGT GCTAGGATTACAGGTGTGAGCCGCCATGCCTGGCCTAGTGATATTTTAAAAAATTTTACT TTATTAAGAGTCTCACTCTGTCACACAGGCTGGAGTGCAATGGCAGGATCTCGCCTCACT GCAACCTGTGCCTCCCAGGTTCAAGCATTTCTCTTGCCTCAGCCTCCCAAGTAGATGGGA TTACAGGCATGCGCCACAACGCTCAGCTAAGTTTTGTATTTTTTTTTTTCTTTTTTAGTA GACACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTG CCCGCCTCGGTGTCCCAGTGTTGGGATTACAGGTGTGAGGTTCTTTTAAGTTTTTTACAT TTTTTTCATTTTTAAATTTTAATCTATATACTTATTTATTTTGAGACCAGGTTATGAGAC TGGCTAGTCTTTGTATTTTTGGTAGAGTCGTGGTTTCACCATGTCGCCAAGGCTGGTCTC AAACTGCTGGGCTCAAGCAATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGA GTGAGCTACCACGCCTGGCCAGTTCTTACTGATATTGAGTGGCTATTATTATTTCCAGTG GAGGACTTACTTTATCCTGAAGAAAACCAAGGGCTTGCTGAAAGATGAGATTATGTTTAT GAATGCTCACTGGTGGAAATATTTCTGCACACTCAAGCTAGTTATGCTTTTTTATATTCA AAGGAATATCTTAGGGTATTATGTGAACACATAAGAATTTAAGGTAATAGTAGTAATTAT CTTAAATCATATTCATTTAGTTCACCCACAATTTTATTCAATCCCCACAAACTCCTAGTA AGGAAAGAGGGGCCCAGAATGGCTAAGTGTCTTACTCAAGGTTACTTATACTCCTCTTCC TAATGATTTAACCCAAGAGAGTCCATAGCAAAGGGTGGTATGTAACTGATCTAGAGCCAT GTTGCCATAGTTTTATGAACATAAGAATCACTCGGAGAGCTTAATAATCCAGACTCTTCT CCTAGGATCTCACTCAAAAGGTAGGGAGTGAGGACCAGGTATCTATTTGTGTTTTCAGCA AGAACCTAGTATAATTGTGATGCATGTGTCCCACAGGAAACTCTGCTGTAAAGGGATGTA ACCCTATGGGGATAAGGGCAGGAATAGGCATAGGAGCCCAAAAGGCTCTTCTGCTCCAGC ACTTGCCCAAGGACAGGTAGATCACAGATCACTTTCTGTGGGCAGAAATGTGCAGGGCCC CTGACACCATGGTTGAACTTCTTCCTATGGCTTTTCTTGCTTTGGCTATCTTGGGCTAGC CTGCCCCATCATCCTGGCTGGTGTTTAGCAGCACATTCACATTGAAATTTGGGAGGAAGG GTGGGTGAGACCTGCTAGATTCCAGCATGGACATTAACCATGTAATCTGCTTTTCTTCAC TGCCTCTTTAAGTGCTACTAATGGAAAGATATGATCTTTTTTTTTTTCTTTTTTGTGAAT GGTGTTCTAGATTCTCCCTGGTATATAAGTTAGACTTGAGCTTTTCCTCATGTATCCCAA ATTCTTTGAAATGTAAGAAAGGGCCCCTCACATAGCATGGTCTGATTTTCTGCAGCAGTG GCTGTGTATGTCTTTTCCTTTATTCTTCTATAGCTCAGAAGGATCAGAAATAGGGCATCC AGTGAGTATTGCCTCTATAGATTAGGAAGAGGGGAAGGGCCTGGGGAAAAGTAGAGAGGG AGATTTTTATTAAAATAGAGACCACATCTATGCTTATGGCACTAATATTTTTAAGTTGGA GAGTAGCTAAAAACACCTTCCTTTTTCTTACTTTTTCATTTTTCAAAAGAAAAATAAAGC CAAATGAACAAGGAGAATGCCGATCTGTAAAAAGAGCAAGCATGTTTGACCAATAGGTCC TGACAGGTGAGGGCTGCTCACTCGGTGTGCCAGGGACCAAATGTTTCCTGCTGTAGCAAC TTTGCTTGAGGCAAGAATCTGATACTTCAAACTCTGTATTCAATATTATTGAGAAGCTCA GCTTGAGCAGTTTTTTCCAGTTTTAGGGCAGCTTTGAGAAATTAATCTACTTCAAAGAGA TCCCTTAGATAAGAAGCAGGCACTTTGAAGCTTTTTTTGTTTTCTCCAAGATTCTAAATT ATGACCCTGTCCCCATATATTATATTGGGATACCAAAAGTCAAACAAAAGGCTGCTTTGA CCTGCAGTAACTGTGTCACATCAATAAAGCTACAAAGAGGTTTGGGATTTTCTTTTCCTT TTTGCCACCCATCTCTTAAAAGCATGAGTAATGGTCACATATTCTCGGAGCAAATAAAAA CCTGCACTGAGAATCAAAGGTGGTTTTAAACTTCCCTAGCACTGATAGTAACGAGGTTGT CTGATTATTTTAAATCTTACAAATCTAGGAGTAGAAATATTAAAGATATTTTATCAAAGA TATACAAATAATAAAGATACTTTGATTGGAAATCCAGTTTTTGGTCTCAGAAAACTTCAT TTCCCTATACCCATTGCCAGAAGTTAGTGAAGGCGTCCCATAGTTGTAGGGAAAGGAGTC CTTGAGATTAATTCAATAATTCCACAAATACTAAGCACCTTATGTGTTCCAGACACAATT TTATACACTGGTAATACAGTGTTTGAATACAAGGTTCTTACTTTCTCAGATGGAGCTTTC TTGTGGGTAGAAGGAAACATAAAACAAACAAGAAGTCATTAGTAACAAGAGTCTCTGTTA CATATGAAACAGAACCACTTTAGATTGGGTAGTCATAAAGCAGACCTTATGAGCAAATGA CATTCAAGCTAAAACCTAGATGCCAAGAAAAGGCCATGAAGATCTGGGGAAAGAGTAGTA GGCCAAGGGAACAACTGGCACGATCACCCCAGAGTCAGAACCAGCCGGTGAGTTCCTGAA GCCGAGGTGGGTAGGGTGGGGGACCATCAGCATCAGAGAAGAGACTGGAGAGAGGCAGAG GCTGGATTATGGAGCCTGTCAGTTTATGGTAAGGCACAGTGGAAATACATCACAGGACTT TACACAGAGGCATATTTGTTTTAATTTGCATTTTAAGAAATCAGTCTTGTTGCTTCATGG AAAATGGATTGTAGGGAGATAAGCAACAAGAGTAGAATTAAAATGGCCCTTAGGGAGGCA GTTGGGACATTGTGGAGGTGCATAGAAGTGAGCAGACTTGGGGTATTAAGATGACACTGA TGAACTTGCTGAGGGATTGGCTGTGTTGAGGGAAGGAGGAACCAAGGATGACCCTTGGAC TTTTGGCTGGAGCAGCTGGGTGAGTAGTAGAGTCACTAGCTGGGATATAGGAATTCTGAA AGAATAAGTTTGAGGATAGCTGATGGGGATGGGTAACAACAACTTGGTTTCAAGCACACT GAGTTTAAGATGCCTATCGGACAGGAAAATGGCAGTGTCCGACTGGCACCTCTGTGATTC TAAATTTCTTTTCTTTTCTTTTCTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGC CCAGGCTGAAGTGCAGTGGCATGATCTTGCTCATTGCAACCTCCGCCTCCTGGGTTCAAG CAATTCTCCTGCCTCAGCCTCCTAAGTAGCTGGGATTACAGGTACGCACCACCACACCCA GCTAATTTTTGTATTTTTAGTAGATATGGGGTTTCACCATGTTGGCCAGGCTGTTCTTAA ACTCCTGACCTCAGGTGATTCACCCACCTTGGCCTCCCAAAGTGCTGGAATTACAGGTGT GAGCCACTGCACCCGGCCTATGATTCTTAAATTTCAACAGAGAAATCAAATCTGGAGTTA GAAGTTTAGGAATCACTACTGTCATTACTTTTTGAAAGGACTTGAGATTACTTAAGAAAG TAGACAGAGGGAAGGGAAGAGATCCTAGGACCAGGTACAGGGTAATCTGACATTTTAGAA TGTAAAATAGGAAGATCCTCCAAAGGACACAGTGAGGTAGGTGGAAAACTTGGGGCCTGG GGTGTCAGGATGCCCTAAAGAAAGAAATTTTTAAAGGAGGGCATAGTGAGCTGTCTTTAT GCCATTGCAAGATTGAATTAAGTAAGTTTATTGAAGTGAACAGTAAAGGATTCTCTTGGA ATTACCTAATGAACATAATATTTTGAAAGTCAGAGAATCTTGACTTTAATACTCTAGGTA ATAGTAGGGTGTCTATAATATAGTGATTAAATAAATACAAAGATGAATAAATGCAAGTTC AGTGCAAATTTTAAATTATTTTTGTTTTTATTGTGGAGAATTTAAAGAGATAAATTACTC CAGGTATGTAATTTGTTAGAGAGATTGTATCCTTGTTTGTTTAGGGGAGGGTAACACAGG GGAAATGACAGCTCCCCTTCCAACCTCAGGCTCTATTAGCATTTTGAGAAGCCAGCTTTG CCACATCACCATTTCTCTTACTTGTGTAATACAAGGCAGAGAATCTTTGCTCTACCAGGT GGAAGATTTGCTTTTTGGTCTCCAAAATTGGAAGGAGTCTCAGCATCCACTCTTCCAAAT TTTATAGAAGGGATTATTTATCCCGGAGGCTCTCAGAACTCTCCCTCAGAATCTACTCCC CATAATGAAAGAAAAAGACTTCACTGTGCAAATTACCAAGTGTCCTTGGTGCTGCAGGGC AAAGGCTGTAGGCAGGTTCCACAGCCTTCCCGAGAGTCAACACTCATGAGTAACTGCGGT GGTTGGCAAGAGAAGTAAACGGCAGTGGTGTAATGTGGATTCTTTTCTCCTCCCACCCTG AAAAACCCACCTGATTAAATATTTCCTTATCTGGCTTTGTCTGTTTACAGGGCTCATCCA TGTCCCTTTCACGGTCCAACAGTCGTGAGCACTTGGGAGGTGGAAGCGAATCTGATAACT GGAGAGACCGAAATGGAATTGGACCTGGAAGTCATAGTGAATTTGCAGCTTCTATTGGCA GCCCTAAGCGTAAACAAAACAAATCAAGTGAGCGTTGTGTTTTATGCACACTTTTAGGTA TCCCCAGATTAGAATGTGTTTATTTGGGTTGGAGTATCACTGACTGTGGCCTCTCTGACT TCAAGTGCTTGGTGTAATTCACATGCCATCTCCTCTGTGAAGCCTCCTTGTTTCTCCCAG TGAAGCAGGCCACCTGGTTCTCTTTCCTCTCACTCCATTTTGTGCGTGCTTTCACTCTAG CACTTGCCATACCAAAGGGCAATTATTTATCTACCTATCTGTATCTCCTTGTGAAATTTG TGCTCCACAAACCAAAGACTGTATTTGTTCATTTTATAAACATTTATGAAGTGTCCATGT GTCAAGTATTCTGTTATGCTCTGCCTTATTGGATATTTCTTCCCAAACGCCTAGTGAACT GTCTGACACCTAGTAGGTAGGTGCTCAGTAAAAGTTTGTGAAATGAATGCATGAATGGGT AATGTACACACATGCATCCAGGTGGTGACAAAAAGACAAGGACATAAGAAAGTGGTTGAG GCCAGGCATGGCAGCTCTCACCTGTAATCCCAGCACTTTGGGAGGTGAAGGTGAGTTGAT AGCTTGAGCCCAGGGGTTTGAGACCAGTCTGGGCAACATAGTGAGATTTCATCTCTACTA AAAAAAAAAAAAAAAAAAACAAGAGGCTGGGTGTGGTGGTATGCATGCGCCAATAGTCTT AGCCTACGTGGGAGACTGAGGTGGGAGGATCGCTTGAGCCCAGGAGTTTGAGGCTGCAGT GAGCTGTAATTGAACCACTGCACTACAGCCTGGGTGACAGAGCGAGACCCTGTCTCAAAA AAAAAAAGTGGTTGAGAAAAATGTGATTGAATTAGCATCTTAGACCATTGAAGAAAGACT GTCCAGCGGGTGGCTACTAAAGGTGAATAGCAGGGTTTGATTTTGTAAATAGACAAGATG TTGCTGAATTCGCATAAACAGGAAAAAATTAACTTATTACAGCATGGGGGTTCTGGCTTT TAGCAAATCTGGCTGAGACTCAGCATAAGCCCATTGTTTTATCTACAACAGCACCCATAC TCCTGGGCTGTATAAACAGATGAGAGCTGACATTGTCATCACAAGATATGCCCCAATGCC TTTTTTCAGGGTTTTTGACAAATTTGGAATCCTGAAACATGTAGAATATTTGAAGACTCC TTGAAGCTAGGCAATCTAGATGAGCATGGTAGACACTCAGTAACAGTCAGTTGTTACGTT ACTATCACTCATGTCAGCTGTATTATCAGGAGTCTCAGATTTGAAAGGAGTAATCAGGTT GTTGGCCAAGTCTAAATAAGAAAGCACGGACAACTATTTCATTCCTAAGTACACTGTCAA TAGTAGCCTGGAGACTTCCCATTAGTTACTGGCTGGACGCTCCACCACTGACAGTATGAT CAAGATGAGAGTCAGGCTGATGCCAGGCACAGATGGAGGGGTGTAAATGATGTCCAGTCT CTAGCCCAAGATACATTCATTTGGTGCTTCTCTTTTTCTATCTTTATCTCCTTTCCCTTC ATTTAACATTGGATAATTAAATTGACTGTACTACTCAGTTGAATAGAAGTTCAGGATTAA GATGGAGGATACATTAATAAAAAGGAATGATTAATGAAGCACAGTTATTTGGGTTTTGTC ACTTTTTTTAGGGTATAGGGAGTTTAAGAGAGACTATAGAAACTACAAGTAGTTAAGACC AAAAAAAAAAAATTTAAGTAAAAGTACGTTATAGGCTACTTTGAACATTTATCACTATGA ACATTTTATTTTCAAACATTTGTTTTTAAAATTGTTAATAATTTAACATATGTAAGATTC CTTTTAAATATGTAATCAATATAAAAATTATTGGAGATAGCTTACATTCTTTCTTAGGTT GTACAAAGGCTTTAAAATCTGCAGTGTATTGTGTACTGACAGAGCATTTTCATTCCCACT AGGCTCATTTCAGGTGCTCAATAGCCATGTGTGGCCAATGGCTACTGTATTGAACAGCAC AGTTTTAGATAATTTCTCTTAACACCCTTGTCAAGGTCACCAATGTTTCCATTTTCCTGG GCATCCCTATTTATACCAGTTGCTGCAGCATAATTCTCAGTAACTCTTTTACTCTCGAAA AAAAAAGTAAATCTATCATTTGGACCATAAATTATATGGGCAGCCTTTCAGCCACTTTGA TGTAGTCACATCCCACATCTGGTGGTCACTCACCCCAATTTGCTTATCGCAGTCCACTTT GTGGCTTTGTGTCACCTTTGACCCGGTACCTCAATAGTCACTCCTCCTCAAACTGTTTTT ATGACTTTGGGGCCTCTGCTTCACCTTTAAATGGTGGAGTGTCCCAGGACTCAGTATCTT GGGGTTTGGTTTTGGGTCCTTTCTCTACACATTCACCCCAAGAGATAAACAGCAGCTATC CTTAAGAGAAAAACCTTTTCAGGAAATGCCTTCTGTTTGAGAATCATAGAGGACATCTCA ATTGGGAGATGAAAACAACTGGAGAAAGTGATCAATGACACCCAAAACAGTGCAGAACAA GATTCCTAGATTTGGCAGACACATGGATCCCCAGAGTAGACTAGATGGATCTGATTGGCT TTGGTCAGTGTTGTCCTCCCTCACCTCTTTGGGGATCTCTCCTGAAGCCACATCCTTGGT GTAAGAAGACAGATTTCCCACACAGGCAAGAGCTCATTATTGGTCTGGGAGGTGGAATGC CTGCACTCTGCTGAAATCTCCAAGGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTGACTTACTTGGCTTGGTTCAATAGTCCGTCACCAGCGCTTGCTTG TCACTGGGTCTGAGAGCCACAGACAGTTTGTTGAAACCTTTGCCCACCAAATCAGTTGCA GAACCAAGGAAAAGTTCAGCATTGCTGTCTTAAAAGTTTTCCCCAGAGACAGATTTATTT TTGTCCTAAATTAAATCCAGGAACCCCAGCATCATTCTTATCACTTTATACATTACTATT AATCTTGGAAGTGTGCTGTTTTGTGACCTTGCTACCCAGTTATATTTTTTAGGGAGCAGG ATTTATGTGTTGCAATACCATACAATTCCTTTGACCAAAGGAAAGCACAGGTGTAGATAC AGAGAGCCACCCTGCCATCCAACGGAGCCTGGACTTGTAATAACTTTCCATACCTTTATT TTGTCCCAGGGATCCTTTTTACAGCTCCTCATTTAATTCACATCCAATCAATTTTAAACA ACAAATGCTTCTGACTACTCAGGGAGAATATGATGAATGATTATTAACTACAGAGGCACT GTTGCTGAATTTCTGCCTCCCAAGTGTAACCTTTTAAATGTCAAGAGCCTCCCTGAAAGC AATAACCAGCATTTCCTTAATGGAAAGCCAATATTTCAGTAAAGGATTGCTGTATTTCTA CAGCTACTGCCCTATTCAGCTGAACAATGGAAGTTGAAATATTTAGGTGATTAAAACTTT TAATTAAACCATGTTCTCTCTGGGCATTTACACTTCAAGCCTGTCTCTCCTTTGCCTTTC AGCGGAACACTATCTCAGCAGTAGCAATTACATGGACTGCATTTCCTCGCTGACAGGAAG CAATGGCTGTAACTTAAATAGCTCTTTCAAAGGTTCTGACCTCCCTGAGCTCTTCAGCAA ACTGGGCCTGGGCAAATACACAGATGTTTTCCAGCAACAAGAGGTCAGTCATTATTTATT TTCCCAAGTATCTTTGTTTTGATTGTGTGTATGATGACTTCTAGAATGAAATCACTTATT GACCTATGAGTATGCTTTCACTGAGCATTTATTCAAGTCTCATAGCTTGTCCTTGCTACT AAGAAAAATGTCATCTCATTTCTTATTTAGTGCAGCTAGTAAACACGGGATAGCAGAAAT AGAGAAAATCATACTTGCAGAAAAATGTACAATAGCTGTCTAACAGTTTTAGCAATAAAA CCCAATCGATATATAGATTCCTAGGAATTTTTGTAGTCACAGCTCCCTTAAGGTCAGCAA CAAGTCTGTATTTAACATGATTTCATTTTGAATCTGTTGTTATCTTTATTTGTGGCACTT AAAAGTAAATAACAGCATCTGAAATATCTCTGGCTGTTTTTGACTCATCCTGGTCATGCT GAAGTCTGTTCTTACAGAATATATGTTTTTTTCAACATGTTAATTTATTCATTAACTTAT TGTTTGGGTTTTACCTGAACTGAGACAGAACTGAGATGTCTACTGAACAATCATGACCAT GGATTTTGGTCAAACTGATTAGCCATATCCTATTATGTACTGGCATAAAGAAAAGAGGCC CCAGGCATGATTCTTCCTAACAGTGCTCTCATATTACTGGGGCACAGCTAACTCAAAGTG TCAGAAAATTAAAATGTTTCTATACATTTGTGTCTTTTTCAAATCAAGACATGGTCCATG TTTGATGCTAGTTGGCTTAATTTTATGTTAGAGAACATCTGATTTAGTCAGTAATTTCTA GGCACGTGTCAGTTAATAAAGAATCTATAGTTTTTACTAGGCACTTTGTATCATAAATTC AATGTACTGCCCATGGTCCAATAAATTATTAAGTTTAAATGCTGAGCATTTTTGTTTTTT ACACTGAAAGGGCAATTGTTGTGTGTATTAAATTTCAGGGTATTGATTTTTTTTTTCTGT TTCCCCTACATCTGAGTTAGTGTTCATTTAACCAAGAATTTTCTAAGCTGAATAAACCTT TCATAATCAGTGCATTAAAGAATATATCTCCTTATTTTGTCTTGCTGGTTAGATGATGGT AGCTGGAAGCAGAAGTATTTTAATGTGTCCAGGCACAGAAGGTCAAAAAGCAAGAGATTG AATGTTAATTCAATGATATTCTGGGTTTGTTTTCATCTATGTTTCCTATTTGAAGAAGCA TAGAAATTGTAGGTATTTCTTATTCCAATTACTCCAAGAAGGAAAAAAACATGAAAGTAT AAAGCCAGAGGGACTTAATGTAATATTTTATTAACTACAGCAGGGGTCAGCAAACTGTGG TCTGTAGGCCAACTGCCTGATTTTGTAAAGTTTTATTGGAACACAGCCACATTCATTTGT TTACATATTGTCTATGGCTTCCTTCCAGCTATAACAGCGTAGTTAAGTAACTGCAACACT GACATTGTGGCCCACAAAGCCTAAAATATTTACCATCTGGTCCTTTAAGAGAAAGCTGGG GAACACTTGAGCTGAAGAATCTCTATTATAGAATTTCTGAAAACATATCTTTAGAACTGT GATAAATGATGGCCTAAGGTTTTCTAAGACCTGGATGTACCTTCCAAATCAAAACAGGAC AATTTAAATTATCTTCAATATCATTTAATGAAAAGTTTTACCTGTTTATGGCATGTTGAA ATTTGGTCATCTGCTTTTTTCAGTGTAGGATATTTTCTAATACTCAGATGTGATTTAACA AGAATCCCCCATAAGTAACTTCATGAGATTTAATTTATTGTAAGCATGTTGAAGATTCAT TTAGCAACTTTCACAGGTGATATATCAACATGCATTATTACTAACCATACCTGCCAATTG TCTTATTTGGTAAGCCCAGTACTTTATATCTATAGTTATAGTGAATGCTTACAACAGTTC TGCAAGATACAGTATTGTCAACCCTCTGTGCCCACAGCTAGTAATGGCAGAGTCAGGATC GAACCCAAGTCTCTTTGGCTTCAGAATCTGTTGTCTTTCTCTTCTTACACACTATCTTTA AAGGAAGGTGGGGGATCCTTGGGCAGTTTCCCTTCATGCTTTGTTCCTGATGCCAGACAG TGCAGTTTTATAGTTCCTGCAAATACTTCTTTTGTGTCCCTTTCAGTGATAGTTTGCTGA GTTGAGCCAAGTGAACTGTAGATCTGATTGTGTCTGGGAATTCTTCTTTCAATCCTTTCA ATCCTGTGTTGAACACAAAGGAAGATGCCATCTGTTTTATTATTTAGTTTCTTCTTATAA AGATAAAGATACACTTAACCAATTTAAAATCCCAACCTAAGAAATATTTTTCTCTTCTCT GAACAGATAATGCTCTTCCTTTTATCAGTTCACAAAAATGGTACAATCTTTGTGTTTCCT TTCTTGCTATAGTTGCCGGGTTGCTCAGAGCTAAGTCTTCTGCTAGAATCATCATTTCCA TTTCACCACCTTTCTTAATTCTTGTTTCTTAGGTTTGTGCTACCACCTTTCTTTTCTGGA AGTAGGCAGAGCATAATTAATAAATAAGTGTGACAACAAGTTGATCCTACAGTGGGAAAG AAAATAAGTAATTAATACATTGGTTATAGATTGACCTTTCTACCCACAGATCGATCTTCA GACATTCCTCACTCTCACAGATCAGGATCTGAAGGAGCTGGGAATAACTACTTTTGGTGC CAGGAGGAAAATGCTGCTTGCAATTTCAGGTGAATATAAATATTCAACTCATATGTTAAA ATCTGAATAACCTCTGCCAGTGGTCTCAGCCATTGGGTTGTTTCTACCCATTAACTGCTG GCTTACTAACCTAACACCTTGGTTGTGGTTTCAGAGGGTTTTCCTGTCAACAGTGTGACA GATCCTGAGACTGTCTTACTTTTTCATCAAGGCATTGCCTGAAAACCTGCCTTAACAAGG GTCATATATGAAAATAGATCTCTTCAGAAAGATCTAACCAAAATCGCCCTATGCAGAACA TGAGAAGTTGGGGAGAAAGTTTAATTCTCCTCTTTGCAGTTGTGTTAAACAGTAATCATT ACATTAGTGAATAATTATTCTTGATTGGCAGTTATGTTTCAAATGTTTGTGTCCTTGCAC ACCGACTGAGTTCATTGCACTGAGAAGAAAAGAATGCTGGTTGAATCTGGCAGTGTTACT TGTCTTAATTCTTCTTAGTCTTCCCACTGTCTTAATAGAATTTATGAGTCACAGGACATA GTATCCTGAAGATAGTCACAGAATGAAGGAAAATAATGTCTGTCTCCCTAGGCCACTTTC TTTGTGCATCTGTTGCATATATATTTTAGAAAATGCTCTATACGTATTTATTGGGTGCCA CTCATTTGAAAGGAATTGAGCCAGATGATGAGTCAGGAGTTGGCAAATACATAGTAATGA ACCTCAAAAAAGCGTTTAGAAAAATATGCGGAAATTTTAAGGAGGGAATGGGATTAGTTT TTGAAGACTTGCCAATAAAGTTCTTGAATGTCAAGTTTATATGTGTCCCAGTCTCAGAAA GACAGACACACCAGGGGCAGAAGCCAAGTGTCATGTGCTGCGGAAAAATGAATGCTTTTT CAGAACACTGAATTTGCAGGCTATGCCTCAGTGAAGCCAGCAGTTACATCCAACTGGTGA AAGTCCATTCCAGACAACATTCACTAATCAGATCAGCAGATAAAATTTAAAACCTCAGTG GTTTTCCATTTTATTTTAGCGGCATGTTGAATGCCCCACCCATCTTCCCATAGGAAATCT TTATCTGAAGCAGATACAGGCAAAGCAGCTTTGAAATAGGAGTGGAAATCCAGCCATTGA GCTTCCTGGTGGCAGCCTGTTAGGTTCTTCTGTGGATAGAGTTCTACACTCATCAGTTTT CCCAGAACTTCTTCTAAAATTTCTTCTCGGATATACTGTGTGTACCCAAGAGGCTCTATT AATGGAACTCCACAGGGAAAATGCATAATTCCTGCTCATAAGATCATCTTGGTATAGTGG AAAGAACACTGGATTCAATTAGGAGATCTGGGCTTTACTTATGCTAAGTCATGAGTCCTT GAGTGAGTTTCCAAACCTCTCTTGGCTTTGGTTTGTTAATCATGAAGGTAGATTGGAATT TGTGATTGTACAAAGGTCACCTTCCATTTCTAAGATCTGTCCTTTCATGTGATATCATCA GGCTTAGTGAAAATGGACAAAACGATAGTTTTATTACTTGTTCTTTTTTACCATCTATGA TAATAGAGTAATTTTTAAAATTTGTTTTCTGTAAAGCTCATCCTCAGGGGGCTATCCCTA GACTCAAGCTAACTTTAAAAGTTTTCATATTATTTTATTAATTTGCAAATGAAATTTATT TGCAGTTTGAAACGTGATTAACTTATGCATTCACCATACCTGTACTGTTGAAATATGCCT GCAGGCCAGCAATTTTCTATCAGTGAAGTGTGTAGTCCAGAGCTCCATAATCTTTCACTA GAGATTCATGGAATAGCAGTGAGGATATAGTGAAAACTAAGTTCATTTTTTGGTGTCCCA ACCCAATTCTGAATTCTGTAAAGATTTTAGCAACAAGCAGATAGCTGTAAATACATTCAC AGGTTGTAGATAGATCATCAATACCTTTCCTCTGGAATATATCAGTATCTTTTGGGGGAG GTAAGATGGGAATCAGAAAGGTTTCAAGCTCTCTATTTTAAAAAAATAATATTTTTTCTA ATCATCTTCTTTGTCATTCTGTTGAGGTTATATAGTACTTTTGCAGACTTCCTCTCTCAG TGGGGTTCACCAGGTCCTCTTGCTTTTAAAGGGAGTTTGAGACTGACTAAAATACTTTAT GGCTGCTCTGCACAGCATAAAGGACTTGATTATTTTAAGAATAATTTTGTCTTACTTTGT TGAGTGCATTTGTTTGAACCTGGTAAATTATTTTCTCTGAAAGCAATACATTTTTATTGA GAAAATTCTTCATCAAAAAGCTTCTTTCTCCAGTTCAACTTATCTCATAACAAAGACATC CATTTATAGTCCCAGAACATTCTGTCTCCCTATGGATGCAGTATAGCTGGGCAGTCTGAA CTCACATTTGTCTTATGGTTATAGATTGGTTAGGTCCAGAGTTTGCTTAAAATTCCTTTT TAAATTTTGTAGATTTTAAACTTATAATCTGAGTGATTCTTTCAGTATAAGGTTTTGTTT TATTTTTAATCTCAGGCCAAAATACATTTAATGTTATAGCAGTAGATGAAATTTATCTCC AATGGAGATGGATCAAAGTATAAATTTGATCTCTTTTTCCCCAAATCCACTTTTTTTTTT TTTGGAAAATTCACAGATTTTTCTCAGAATATTTTCATGATTGGTCAAATGTACAGGGAC TCAGTGAAAGGACGCTTAGCATCCTGTTGACAGGCTTCCCACCACGGCCTCAGGTAGATC TAACATTTCCCGACCTATTCTTTTAGTTTGTGACTCTGTTCAGATCCGCAACAAGATCCT GAGAGCTGCCAGGATTGTGTGAACCTTGGAATTTCAAAGAAAAAGGTTGGTATTTTCCCA AACCATCCCGTAGGCTTACTGAAAAATATTAGAGGAGTTTGCCTTATCATTTAAACAACA ACAACAGCAATTCTAAAGTCTCTTCAGTAGGACTTGACCTTGATAACCTCTCTGGAAGAT TTATCTCTGTGCATCACATTTAAAAACATATGTATGTACTCTCTTAGAAACTGTATCGAT TAGGGTTGGATTCCCTTGTGATCATTTTACTGTTTCAAAGATCTAGCTGATGTGTCTTTT CAGAATAAAGTTTTTAATATTTATTTTGAAAAACTTTGTCTTCATGGCCCAGTTGTTGTC ATGTGCTCAGTTATACATGTTATATATGCTAAAGGAGAATGTTGTTTGGCCTCATTCCTT TTTTTTCTTTGCTGTAAAGTGGGAATGTCTTCCTGAATTGTATGTTATTCCCCCGTGAGA AAATGGAGGCCGAAGATAGTCCCTAGCTTGAAGATGATAAAACTTTTCCAGGCTGTGTAC TTAAGGGGATTCATTTATTCTTAACGCTTCTATAAGTTTGCCTTTAAATATATTCAATTC TGTCTTGATTTCTGAATTTTGAAGTGCTGTGTTTGTTTTTAACAAGATACATGTATTCAG CTTTTAATAACTGTGTTTCTGGAGGAACTTGAAACAACAGCCATCTGTATGCATGCCTGC ATGTGTCTTTTGCTTGTAAAGATACCTTCCTTGCTTCTTCAGAGTGAAGCTGGGTTTTTC TATTTAAAAATTAAATTTGGCATGTTAAAATAGCAAATAAAGCTCTGTTATCTGGCATAC TTGGAACTATCGATTTCTCAGATTTGTATTCCTGATGCCTTGGTTGGTCTTCTCTGTCCA GTGGGTCACTGAAGGCCAGTGCTCAGGGCATTGACCTTTCCATCAAGCATGTGAGGTTTC ACCTCTGTCACTTAGTACCTGTGTGGGCAAGTGACTTAGTCTATTTTTTCAATCAGTTTT TTCACCTATAAAATGGAGAATGGTAATATTATCTATCCCTTAAAGAAGACTTGAATAGGG CAAAATAAATGTAAAGTGCTTGTCATACAATAAGGCTAATGAATCATTGTTATTTTTCTT CTCTCCTAAGACCTATATATGAACAAAAGAGAGATGTCTCCAGTGTTGCTTTGACCATAT AGGGGCAGGCGTTTACATTTTGGAAGGCAGTGGGGTAAAATGTGAAGGGTATTGGTCATC CTCCAGAACTTGGCCATAGGAGTGTGTCTGGTCATATGGTCATCCTTAACACCATGCAGT CTGTTACAACCTGAATCTGTGTCGTCAGCATTACTGTAGATGGCCATATCTTACATTGTA ACTTCACAATTCAAAAGGGGATTGATTGTGTGTGTGTGGTTTAAAAAGTACTGAGTACCA TGCAAATATAAGGTGAATCACTGCTCTAGCCCCTCAAAGAGACAACTTTAAGCAAATCAG TTACATAATCCCTCTAATCTATTTTAAACTGAATAAATTTGAGGGTATTTGCATTTGTTT GGTATCAAAACCCTAATTTCCATAGTCTGATGATTCTGTGTACTTGCATGAGTTTGTCAG AATGAGTTACATCAGTGATTTTGAGGTGGGGGCGGAGGTTGATGCATACTCATAAAACAA CGTAATCTGTTTCAATTAACTTTTTACCTTTCCAGTTAATAATTTTAGTTGGCAAAAGAC AAACCAAAACAGTGTTTTCAGAGTACTCTAATTTCTTTACCATTCAAATAGGGCACCTCA GGTTTTCCCTGAAATTTTAGATTCAAGTATTTGTTGTTTGTGAGTATTAATTTTCTAAGC TGATATGATTTTTTTACTAGATTAATTTTTTATTCAAAGAAACCTACTCATATGCCTCTT TCTAAAACTATTTCTGACTCAAGAAGTATAGGGTTCATGAGTTGGCAGAGCCATGGGGGC TGTGGCTTAATACAGTTGACCCTTGAACAACATGGATTTGAACTGCACAGGTTCACTTAT ACACAGAGGTTTTTCAATAAATATATTGAAAATATTTTTGGAGATTTGTGACAACTTGAA GAAACTTCCAAACTGCATAGCCTGGGAATATTGAAAAAATTTAAGAAAAAGCTAGATATG TCAAGAACGCATATGTATGAAATATATACAGATACTAGTGTATTTTATCATTTACTACCA TACAATATACACATCTATTATAACATGTTAAAATTTATCAAAACCTCACAGACCATATAT GGCACCACTGGCAGCAGAGAGAAATGTAAACAGACAAAGACATTTTAAATCATAACTGCA TAAAATTAACTGTGTTATATACAGTACTGCTGTAATAATTTCATAGCCACCTTCTGTTGC TATTGCAGTGAGCTCGATGTTACAAGTATCCGCTTAAAGCACTATATGACACTAATTTCC ACCTGAGCAATTAATCTCTCCAGTAAGTTGCATATAACAGTTACAAGTGATCTCTCACAG TTCTTGAGTATTTTTCATTGTGTTTAGTACAATACCATAGACCTTGAATAACACCGTAGG ACCCACATAAAGTGCCGCTAATGCTCTCAAAAGCAAAGTTATGACATCATGGGAAAAAGT TGAATTGCTTGATATGTACCACAGATTGAGGTGTGTAGCTGCATTTGCCCACCACGTCAA GATAAGTGAATCCAGCATAACAACTATTGTTTAAAAAAAAAAAAGGAAAAGGAAATTTGA GAAGCCATTGCTGCAGCTAGACCTGCAGATGCAAAAGCCTTGCACTTTTTGCAAAATACC TTTTTTATCTTGCATTGAAAATGCAGCTTTTAGAGTGGGTGCAGGATTGTTATAAAAAAG CATACTTATTGACTCCATGATTCAAGAAAAAGCAAAGTCATTATATGACAACTTAAAGCA AAATGAAGGTGAAGGATCTAAAGTTGGAGAAATTAATGACAACAAAAGATGGTATGTTAA TTGTAGAAAGAGGTTTGGCTTAACAAATTTGAAGATAACAGGATAAGGAGCTTTTGTCAA CCACTAGATACCACATGAGTTCCCAGACACGGTTAAGAAAATCATTGAGGAGAAAGACTA TACACCTGAACAGGTTTTTAATGCAGATGTAAGTGTCCTATTCTGGAAAAAAAATGCCAC AAAGGATTTTTATTAGTAAGAAAGAAAGGAGGCCGGGTGCGGTGGCTCATGCCTGTAATC CCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACAAGATCAGGAGATCGAGACCATCCTG GCTAACACGGTGAAACCTTCTCTCTACTAAAAATACAAAACAAAAAAAAATTAGCCAGGT GTGGTGGTGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGACATGA ACCCGGGAAGCGGAGCTTGCAGTGAGTGGAGATCGCACTACTGCACTCCAGCCTGGGCTA TAGAGCGAGACTGTCCCAAAAAGAAAAAAGAAGAAAGAGAAACAAACACCCGAATTTCAG ACAGGAAGGGATAGGCTGACTGCTGTTTTGTGCGAATGCAGTCACGTTTATGATCAGGAC TGCCCTTATCTATAAAGCTGCCCACCCTTGAGCCTTGGAGGGAAAAGATTAACACCAGCC GCCAGTCTTTTGGTTGTAGCACAAGAAGGCATGGATAACAAGAATGTTTTCTCTAGACTG TTTCCATTGATACTTTTTCCCTGAAGTCAGGAAGTAACTTGCCAGTAAAAGACTGACTTT TAAAGTTCTTTTGATGTTGGATAATGCCCCTGGCCACTGAAAACCCCATGTGTTTAACAT CAGAGTCGTCAAACTAGTTAACTTGTCTCCAAACACAAAGTCTCTAATTCAGCTTCTAGA TCAGGTGGTCATAAGGACCTTAAAGGATTGTTACACATGGTACTTTATGGAAAGGATTGT CAAGGTTGTAGAAGAGAACCCAGATAGAGAAAACATTATGAAAAGCTGGAAGGTTTACAC CATTGGAGATGTCATTGTTGATACAGAAAAAGCTGTGAAGCCATCAGGCCTGAAACAATG AATTCCTGCTGGAAAAAAACTGTGTCCAGATGTTGTGCACGACTTCACAGAATTTACCAT AGAGCCAGTCAAGAAAATCATGAAAGAAATTGTGGATATGGCAAAAAAAATAATAAATAA AGGTAAAGGGTGAGTGAGGGATTTCAATATCAGATCTTGGAGAAATTCAGGAGCTAATAG ATACCACACCAGAGGAATTAATAGAGATGACTTGATGGCGATGCATGTTTCTGAACCAGT GCCAGACGATGAGGAAGACATAGAAGAAGCAGTGCCAGAAAGCAACTGATGTTAGACAGT CTGGCAGAAGAGTTCCGATTATTCAAGACTACTTCTGATTTTTTTAATGACATGGATTCT TCTATGATAAAACAGTGGAAGAATGACTAGTACCATATAGAAACATTTTTAAAGAAATGA AAAAAGCAAAAATGGCAGACAGAAATTATGATGTATTTTTGTAAAGTTACACCAAATGTG CCTGCCTCTCCTTCCACCACCACTACCTATTGAGCCTCTACTATGCCTGAAACAGCAAGA GCAACCCCTTCTCCTCCTCCTTCTCAACCTACTCAACGTGAAGACAACAGGGATGAAGAC TTTCTGATGATTCACTTGCACTTAATGAATAAGTAAATATATTTTCTCTTCCTAATGATT ATCTTAGTATTTTCTCTGGCTGAGTTTATTGTAAACATGTAGTATAAAATACATATAACA TACAGAACATGTGTTAATCAACTTACTGGTAAGGCTGCTGGGCAACAGTAGGCCGTTAGT AAAGTTTTGGGGGAGTCAAAAGTTATACATGGATTTTTGACTACATGGGAGCAGGAGGGG TTTGGTACCTCAACCTCTGCATTATTCAAGGGTCAGCTGTTCTTCAGGGTGCTCCTCCAA TATCCCTGTGCTTAGGTATGGGGTCTTCTTTTTCATATCTGACTTTAATAAAACTAAATG ATTGCCATGTTTGACATGAATGAGTTCAGTAGCTGTAATAATTTTCTGTGCCATCAGTCA TACGTCCTTTCACGAGCTTAGCTTGTTCTCCTTGCCTCTGAAATGACCTTTGGAGTAGGT CAAACTATTTAATTTGGTTAGAGCGTTCTGAGAATGGTATATCCTCCAATACAGTTTACA AACTATAATAGAAACTGTTTGCTGTCAGGAGTTTATGAGTTGCAACAAAAACTATTTGCT GTCCTTTGTTCTCTAGACTATCAATATGCTATCTTTAATACCATACTTTCTAGTATTTCA GAAATGCCTTGACCATCAACTAAAAGTTTTCCTTTTGATACCAGACTTGACTTTCCTCAA AAAACCTACCACGTCACCATTTTCTGAGCTCTAGTGCCATGTCCTGTAGTATACATAGAA CTTCTCTTGAGCTCCTAACAATTCTCTCTTTCTCTCTCTAGAACTAAATAAAAACCGAAG AAAGCTTTTTGAATCGCCAAATGCACGCACCTCTTTCCTGGAAGGTGGAGCGAGTGGAAG GCTACCCCGTCAGTATCACTCAGACATTGCTAGTGTCAGTGGCCGCTGGTAGCAGCACCC TCTTGGCACATGCCCGCTGACTAACTGTAAAGTGGACACAGGAGATGTATGAACAGCCTT CACAGCACACCATCCTTAGCACTCTGGGTGTCTGGTATCAGGACCAAAGCATTTTATTCG CACCTGTACTTTATGGCAAAAAGGAAGAAGAGAGAGAAGATGTTCTTATGATGTCATACA GAACACCAAATATGGATTACTTTTTTAAAATGGCAGTTGGACAGAATTTGCAATATAAGG ATAGGGCTTTATTTCCTGTTTTTATTTACCTATATAACATATGCACTGATGATTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTACTTAAAATGAAGGATGAATTGACATCTGGGATGCCA GAAGACTTAGAAGTTATTTTGTTTGCTTGTTTTGTTTGGGTATTTGGGGATTTTTAAAAA ATAATCAAAGTGGAATTTTCTGGTACTGCTTTAAAATAATTATTGTGGTCTTTCAGCACT TTACACGTTCTAATTTCTTGTCCTATGGAAGTTCTCGCTGTCTCCATCTCTCTCATTTTT GTGTCACCTAATATGTTGGTACAGATAAGAGTTAGTCACATTTTTCTGACTGCATCAAAC TTTTATTTGAAATGGTACTGGATCTTAGTTTCTGTGCAGAATATTCTGTGATTTTGGGAA ATGTAAGTGAGTCCACTTGCTTCTGGACCAATTCTGTTTCATGTATGTTAGCATCCTAGA AACACCTAGCAATGGACCTAGTTCACAGTAATAGGTGCAAAGAAAGACCAAATGGACTTT GCAGTATTAACCCTTTGCAGTCGTCATACTTAGCTGCTGCCTGTAATGCTAAAATGATTT TAATGGTTGTCTGGAGGCAAAGGGCTGTTTTTTAGTATATTGCCACTAAAGGACATTTAT TTATATCAAACTTTTATTTTTAGATATTATAAGCATACAGTACATAATTGATGAAATTGA TATTTACTAGAGATTTATGGTAGAGAATGGACGACATTCAATAACTGGAGCCCGAGATTG TCACTTTATTTAAAAAGACAAATAATCATCTGACAAGACAGCACTGTTGCCATTATAAGG AGAAATAGATTACAATCCTTATCATGTACACGTTAGCTATGTTCCGTATGGCCACAGGAC TTTCCTGAAACCGTATCTGTCTGCTTGAAGTAGACTTATGTTTGTTGAGAATGAACAGGC TTATTTGAGCCTCCAGGGTGGCAGTTCATAAAGACAGCTAAGTTCTGAAGGAAAAAAAAA ATATATCTTTTTAAGTGGCTAGAGTCATTATTACAATCTTATACTGTGAAAGTCCAAGAA ATCAGGCAACATTGTTTCCTGGGTCTTTTCAGAGATCTTATAGATTTATGAAGTGTTTTT AATCCATGAAGAAACACTAAAGTGCCTTTCTTTCTTCAAAGCAATATTATTTCCAAGTAT ATTAATTTGTTAGAAAACTTTCCCATAGGAAATGTTGTCAAGTTACCTGTACTGTAAAGA GTTATTTATGTTCAGTAGTCAAGATTTTCTACATGGACATAAACCACTCTCACGTGCTCT CAGCAGAAGGCATTAGATAAGCATATACAAGAATTGGGTACTTTTATACAAATATGGGAT AAGAAATACTTGCCTGACACTTTTCCATGGCTGAGTCTGACCATTACAGTAAGAACAAGA ATTGAAGAGGCATTTTGCACACAGAAACATTCTCACTTTAAAAAATGGTATTGGTTACCT TGAAGGCATAGATAATGGGCCTGTCATAAAATTATCAATTATAACTGGCACCGAGGGACT GCCCTTTTTAAGCTAAACTAAGCCTTATCTGCTTAAGGATGTTGAACTGAATCACTCCCT TTACTCATCCTGTGCATATGTGTACAAATGGTCATGTGGATCATGTGATGATCATCCATC TTATTTGATTGTATTAATGCATCATGCTAAACATGTAGTACAGGTTAACAATACCAGATT TATGTCCTGTTCAACAACTCAGTACTCTAAATGTTGTTATGCTTTTAATAAGACCTTCCC AGATAATAATCTTGGAGCTCTTTTCCCAGCTGTCTACCATGCATTTGCAACAGGAGGAAG ATGTAATGAATATGCAGTATTAAGTTGATTTATGAACAGTGCTTTGATATGCCAAAGGGA AAACTGTCCCACTTAAATTAGATTAAGTAGGGTGGCTAAAAATAAATAAAAACACTGGAA ATTCTTTCTCTCACTTTCTCTTGATGCAATGAAGGGAATATGACACTACAGTATACAGAG TTGTTGTTATATGATGCACAAAATATTTTGATGATTTGAATAAATGTTAACTTTTAATCT GCGCCTTAATAATGACTGGTTATCTGTAAATATAGAACAGATACAGATTGTATTTTTCTG TGGGTTTTTGTCCTTTTAGTGATTTTTTTCCAAAAACGAGAGATGGAATTAACATTGAAA ATGGGAAATTTTTCTAACTGAATCAATTGTTACATGAAAAATAAATTTATATAACCCCTT TGTATTGCTCTTGCTATATGAAGCGTGTCTTTTTTT bcftools-1.21/test/csq/ENST00000263103-INS/ENST00000263103-INS.fa.fai000066400000000000000000000000231467060157400225660ustar00rootroot0000000000000010 318336 25 60 61 bcftools-1.21/test/csq/ENST00000263103-INS/ENST00000263103-INS.gff000066400000000000000000000157451467060157400222250ustar00rootroot0000000000000010 ensembl_havana gene 21 318316 . + . ID=gene:ENSG00000122870;Name=BICC1;biotype=protein_coding;description=bicaudal C homolog 1 (Drosophila) [Source:HGNC Symbol%3BAcc:19351];gene_id=ENSG00000122870;logic_name=ensembl_havana_gene;version=7 10 ensembl_havana transcript 21 318316 . + . ID=transcript:ENST00000373886;Parent=gene:ENSG00000122870;Name=BICC1-002;biotype=protein_coding;ccdsid=CCDS31206.1;havana_transcript=OTTHUMT00000048150;havana_version=2;tag=basic;transcript_id=ENST00000373886;version=3 10 ensembl_havana exon 21 214 . + . Parent=transcript:ENST00000373886;Name=ENSE00001609109;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001609109;rank=1;version=2 10 ensembl_havana CDS 25 214 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 107736 107782 . + . Parent=transcript:ENST00000373886;Name=ENSE00001642778;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001642778;rank=2;version=1 10 ensembl_havana CDS 107736 107782 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 188955 189024 . + . Parent=transcript:ENST00000373886;Name=ENSE00001782108;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001782108;rank=3;version=1 10 ensembl_havana CDS 188955 189024 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 271882 271961 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461858;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001461858;rank=4;version=1 10 ensembl_havana CDS 271882 271961 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 273804 273962 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461857;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001461857;rank=5;version=1 10 ensembl_havana CDS 273804 273962 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 275251 275304 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461856;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001461856;rank=6;version=1 10 ensembl_havana CDS 275251 275304 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 276143 276337 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461855;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001461855;rank=7;version=1 10 ensembl_havana CDS 276143 276337 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 276563 276814 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461853;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001461853;rank=8;version=1 10 ensembl_havana CDS 276563 276814 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 280365 280496 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461851;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001461851;rank=9;version=1 10 ensembl_havana CDS 280365 280496 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 283221 283407 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833895;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00000833895;rank=10;version=1 10 ensembl_havana CDS 283221 283407 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 285280 285441 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833896;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00000833896;rank=11;version=1 10 ensembl_havana CDS 285280 285441 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 285937 286133 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833897;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000833897;rank=12;version=1 10 ensembl_havana CDS 285937 286133 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 287075 287207 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833898;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00000833898;rank=13;version=1 10 ensembl_havana CDS 287075 287207 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 287771 287927 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833899;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00000833899;rank=14;version=1 10 ensembl_havana CDS 287771 287927 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 289958 290123 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833900;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00000833900;rank=15;version=1 10 ensembl_havana CDS 289958 290123 . + 1 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 293465 293504 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833901;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00000833901;rank=16;version=1 10 ensembl_havana CDS 293465 293504 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 293885 294039 . + . Parent=transcript:ENST00000373886;Name=ENSE00000833902;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000833902;rank=17;version=1 10 ensembl_havana CDS 293885 294039 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 300711 300867 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461845;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001461845;rank=18;version=1 10 ensembl_havana CDS 300711 300867 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 304443 304603 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461841;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001461841;rank=19;version=1 10 ensembl_havana CDS 304443 304603 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 307250 307349 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461839;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001461839;rank=20;version=1 10 ensembl_havana CDS 307250 307349 . + 0 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana CDS 315642 315772 . + 2 ID=CDS:ENSP00000362993;Parent=transcript:ENST00000373886;protein_id=ENSP00000362993 10 ensembl_havana exon 315642 318316 . + . Parent=transcript:ENST00000373886;Name=ENSE00001461838;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001461838;rank=21;version=3 bcftools-1.21/test/csq/ENST00000263103-INS/insertions.txt000066400000000000000000000024771467060157400222360ustar00rootroot00000000000000280440 A coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 280440 A coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315639 T splice_region&feature_elongation|BICC1|ENST00000373886|protein_coding 315639 T splice_region&feature_elongation|BICC1|ENST00000373886|protein_coding 315640 A splice_acceptor&feature_elongation|BICC1|ENST00000373886|protein_coding 315640 A splice_acceptor&feature_elongation|BICC1|ENST00000373886|protein_coding 315641 G splice_region&coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315641 G splice_region&coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315642 A splice_region&coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315642 A splice_region&coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315771 A coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315771 A coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 315772 G feature_elongation|BICC1|ENST00000373886|protein_coding 315772 G feature_elongation|BICC1|ENST00000373886|protein_coding bcftools-1.21/test/csq/ENST00000263103-INS/insertions.vcf000066400000000000000000000031301467060157400221600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##ALT= #CHROM POS ID REF ALT QUAL FILTER INFO 10 280440 . A . . END=280440;type=ENST00000373886:60553319-A-;EXP=coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 10 315639 . T . . END=315639;type=ENST00000373886:60588518-G-;EXP=splice_region&feature_elongation|BICC1|ENST00000373886|protein_coding 10 315640 . A . . END=315640;type=ENST00000373886:60588519-G-;EXP=splice_acceptor&feature_elongation|BICC1|ENST00000373886|protein_coding 10 315641 . G . . END=315641;type=ENST00000373886:60588520-G-;EXP=splice_region&coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 10 315642 . A . . END=315642;type=ENST00000373886:60588521-A-;EXP=splice_region&coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 10 315771 . A . . END=315771;type=ENST00000373886:60588651-A-;EXP=coding_sequence&feature_elongation|BICC1|ENST00000373886|protein_coding 10 315772 . G . . END=315772;type=ENST00000373886:60588651-G-;EXP=feature_elongation|BICC1|ENST00000373886|protein_coding bcftools-1.21/test/csq/ENST00000269081/000077500000000000000000000000001467060157400166525ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000269081/ENST00000269081.fa000066400000000000000000005455661467060157400210320ustar00rootroot00000000000000>17 17:69147115-69327244 TTTGTTTTATTATATTTTTGCCACAATAAAAAAAATTAAATGGATTGAGACACTGAGAAT TTATGGGCAATAACTCTATATTCATTTTATTTGCAACAGTTGTTTTTTTTTTTTTTTGCC CAATCTAACACAATCCTGCTAAATTTTCTGATTCATTTGCTTCTGTATTCATCCAATCAA TGTTTCATATTGCTCTGCTGCAAAATCTGCTTGTTGGAAGCATGTGAAAGTCAGCAACTG CATGTCAGCTCTGCTTCCATCAGGCCTATCTTCTTACCGCTGCTTCTGACTTTAGGGTGG TTTCTGTGGCAGTGGTCCTCCTGTCACTTTTGGAACAAGACACATTTTGCATTGAAGTTG TTGCTTGCCTGACGTCCTATCTTCCCAGGTGTTTCACAGGACACTTTTAGGCTGACTTTT TCAGTTGGGATTCTGAAACCACAGGTTGTACAAGAAGCGTGGTGCCAATATCTGCATCCA GTGAGGCCTCACACTGCTTCTACTTGGCAGAGGTGAAGTGGAGCCAGCATGTGCAAAGAT CACATGGTGAGAGAGGCAGAGAGAGGGAGAAGATGCCAGGCTCTTTTTAACTACCAGTTC CCCTGGGAACTAACAGAGTGAGCACTCACTCATAATTGCAAGGACAGCACCAAGCAATTC ATGAGGGATACATCCCTATGACCCAAACACCTCCCACTGGGCCCCACCTCCAACATTGGG AATCAAGTTTCAACATGAGATTCACAGGGTCAAATATCCAAATGATAGCAGATGGATAGT GACTTTTTTTTACAGGTCAGAGAATAAAGTTATATGGATCTTACAGAAGAGAGAGAACCA TCAGTTGATATCTTAACCACTTACCTTAAGACTCTAATGAACAAAACATAAGAAAAGTCC ATCAAAGTTTTATTTCTAAGAAATAAACTTGCATATAACCCGAACGTAACAACTCTGGTA TTACATCAATACAGCTATAACATTAATGCAGCAATTATATAACACAAAAGTGCTATAATG ACATGGGAAATGTTCATGAACTGTGAGGTGAAAAGATACAGAAAATGACTATGCCTACTG ATACTACCTTTGAAAAAGGATCCATAAAAAATACATTGAATATAAGTTGGCTAAAGAAAA TATTAACTGCGGTACTTTCTTACAGATTATGGCTATCTTCTTCCATATAACTTCAATATG TACTAAAATTCACATGCATTTATTTTATAATCAGAATGTCATTATAATTAAATGTTATGC TGTGCCATTTCATCAGTTTATCAGACCTTCTTATAGTCAATGTCACATTAAATTAGAATC CGAGTAAATAATGTTTAAAAATAGCTGATACATTTGAAGTTCAGGCTAAAAACCTCATAT TTTTATTTGTAAAATGTTCTCAGTGTTAGCTTTATTGATAATAACCGATAACCAACCTAA TATTGTATGATTTTTAAATTATTTTTAAGCACAAAATAGACCCATGTTGGGGATGAATAA CATGTCTGATTTTGTTAATTTTGTCTACTACTTTTCCCTATATTTCCTTGTTTCCTTCAT CCTAAATTTTTAAAAATGAAAACTGTAATCATTATTGAATGTTTATTAAATGTTTTCTTT TGTTAACTGAAGTAAAAGGAAACATTCTTGTAGAATTATGGAAACTAACAATGTAGTAGG ACCTAAAATTGAATGTTAGGAGGTTCTTCATTTTAAGGGTCTTCCTGTGGGAGAAGTTTC CATTCAACTGTTGTATCAATTTTATCATCAACATTTCCCAGCTCCTGCTCTTTACAGAGT TCTAAGAATACCTAAGTAAGAGAAAATAAAAAAGATACAAAAATGTCAGGGTGTGTCTGA AAGATGGATTCACACAGAGGTCATCTGGATGGTGCTCACTCGTTCAATGAAAACCCACCT GCTCCAAGGTAGCCTGAGAGAGGCTGTATTCCTCCAGGTTGAAGGTCTGTTTCACTGCAT GTAAAGAGACTGACATTAGTGGCTTATATATTTTTCACCAAGTGTTTGTAAAGTCATACA ATAGAGACAGTAGCTTCAAATTGTTTAGATACTGTAAGATATAGGCCAAATAATTACATT TTCTTGAAGGATAAAGAAGAGTGGTGATATGGCTAATAAAAGATAGCCATGCATGAACAT ATTCAGTTTCCTATAAACTCGAAAAAGCTCCTTGTGTCCTATTTTAGTATTATCCTTTTG ATTCTTTACATATATGCTTTGGACTCCAAATCAGTTGTCGAGAATAATTTATTCTATATT TGTAAATCTACAGAGGAGTCCACTCCATGCTGGCTCCCTTTTCACACTTGTACATTCTGC GTCAATAGCCATAAATACGCAGTGTCTCTGGAACTAGTTCAGAAGCCCCTCTTCAATAGT GACTTGTTACACCTCACCCCTCTGTGTTTTCTTTCGCTGACCTTCACTCAGTCCTCCAAC TGTTGCCTCTGTACATTTGCTCCTGGTACCTTGGCTTTTAGAAACATAGAGACCTCAAGA GCTCCCCTTGATATTCTTTGGGACAACATTCTCATAATTATCCTTCAATTCTATGCACGG GTGTCATGGTAAGAAACAGCCCTGGTACCCCAATTCAATCCTGCAGGATAGAGTAACCTG ACTGACTTGTGGCTGGGCTTCCTGGTCAGCACAGGAAGAATCAGGTGGAACAAACCAACA TCTAGGACCATGACTTCATTTCCTTTGAGATTGTTATGACTATCCTGGTAGGGATTTTTC AAGTTTTGATTGATTATTTCATTGTTCTACTTCAAATTACATAGTCTATATTCCACATGA AAATATGCAACCAATACATAAAGTCTTATTTATATATACCCAAACTTACTCGCCTCTAAC TTGAAAAAGGCCCGAGATAGAGGGTGGACATCCTCCACAGGTAACTTATACGCCATTAAA GAGGAATATCTGTCAGGAAGAAGAGTGAGATTTATTACTAAGTTTCAGTGTGATAATACG GGGGAGGAATTAATAGGCAAAGTAAAATAATTTTTCAATGTGTTCTTTAAATAAGTGTCT GATTTGATATAGCATGAATCAGTGTGAAATTACAGATTCAATCATAAAAAAAGTTATAAC AACAAAAATCTGGTTGCCTCTAATTTTATGTTAAAGATAAATTCTGAGAAATAGCTCTGA TTAAGAATCTTTCCCACTCAGCCTGCACTTTGTTATTGTGCTATATTTCTTACTTACTCT CAAAAAGCAACCTTTCTAGAATGTTTACATTACCTTTCCCCTCTCTCATAGGAGAGATTG AGATTTAATTTTCAATCTCTCCTATAAAAATTAAAATATGTTGAACTCTCTCCTGCTAAA AAAAAATTTTTTTCTTGACCTTCAGACCCCCTTTCATGTTGCACAATCCAAGGAACACTC TTCAGTCCTCATTTTGCAAACTTTTCAAAAGCATTAAATAAAATTGTACACACCCTCCTT AAAACAAACATACTCTTTCTCTCTTAGCTTCTGAGACAACCACACTTACGATTTTCCTTC TAACTCTCTAGGCCTGCACTGCTTAATAGAGTAGCTATTAAATCCATGTGGCTATTTAAA GTAATTAAAATAAATAAAATTGAAAATTCAACTCCTCATTCACACCAGCCACATCTGAAG TACTCAGTAGCTACGTATGTGTAGTGACTACCATCCTGGACAGCACAGAAAGGACATTTT CATTATCACAAAAATTCTACTGGCCAATGCTGTTCTAGATACTCCTCAGTCTTTGTTGGT ATGGTTGTGGTGGTACTGTCCACACAGGAAGATTTATTTTCTTCCTCAATCCCATCTCAA AGCTGAGAGCTCCTGGGGTTCATCCGACTTCCTATCTCTCTTGTTGGCCTCAACATTCTC CTAGTTTAATGGTCTTCTATATGGTAAAAAAAATCCCCCACTTTGTTTGTTGCCAGACCA GATCTCAATGACCTCTTCCTTCTCTTGTGAGCCACAGGTCTACATCTCTTACTTTGGCAT CTCCACTTGGATATCTCTTTACACATCAACTACATGAGCTTTTGTTTCATCCTTGACATT TGTAGAATTCATTCTTGACCTAAGTTCTTTAAATGTGCTGTTTCCTGGAAACAGTGTCTG TTACTCCCACTCTTCAGCTGACCAAACCCTGCTCAGTCTTAAAGTCCTACCTCAATGTCA TATCCTCATTTATTTGTATCTTCATTTGCTTAATATCTTCACCTCCAAAAGGAAGAACCT TGTCTATTTTGTTGACTATTCAATACACAGCCGGCAGCAGATAATACGTATTCAATAAAT ATAACAAATATTATAAAAATAAATGAGTAGAAATGGTATACAAGAAAATTCTGTTCATCT TTCAATTAAATTCAGCCTCATTCTGCTATTCACAAGGGTTTGATTACCATTACTTGTAAC ACATGGTTGACCACATACAACTTTAAAAGAAACATTGGGAGGATCAAATGATTTATAATT GAATAATTTAGGATAGAGTCAATCCTTCTCAAGCATGGAAGTCTGTGTTACGGAGCTCTT GATGCAATTTATATTCAGCAAAATCCTGTAGGTGAAAGCATTGTTTTCATTGTCTATTTT TTAAAAATCATTAAAAAGTTGATAGTTTAATTTGTCTGTACTTTGTTCTTAATCTCCAAG CCATTCCACCATTTACACACATATATGAATGCACACACACACACCATTCACCTTTTCTGA GGTCTAAAACACTCACTGAAAATAACTGTTTAGTTTTTGTAACGCATCCTAGCAATCCTC AAACAGGTTGTTTTGTGATGAATAAGTCCACTCTGCCTTTCTCTTCCGGTTTAGACTAGC ACAAAACTAATTGATGCTAATACTGGAAAACACTCATACTTGTCACTCAAACCGAAAACA TCCTTTACCTTTCCTGCCAAGCAGCCTGTGGGAAAAGCTTCAAAATCTCTGTGTGGAGAG CTTCCACCTGGGTAGGTTCTTTCATTTTTATTTCTAGTAAATAATCTCTACCAAACTTGT TTTTCAGATGTTGAATGGAACCAATACACCTAGTTCAGGGGAAATAAAGAAAAAATACTT GTCTCTTAATTTCTTCCTCGGTTCTCACTGTAGAGGAAGGTGTTTAATTACAGGTTAGGG AGCTGTAGAGCATCAGCTGTTCATAGCAAACTGAAACTCTCTCTATAAGAACATGCTAGT CCCATGCTGGTCAGGACAGGCACCCACCTTAGCGTTCCTGACACCATCATGGCCATACGG TCACACACAGCCTCAGCCTCTGACATGTAATGGGTGGTCAAGAGGGTGCCCCTCTCCTTG TTTTTAACGGTAGCCTGAAGTATCTGCCTAAAGATAAAGTAAGGGATTGTTTGCATTTAG AAAGTAATTTGGGGAAATAGATAAATAGAAAAAAGCAGGAAATCTAAAGAGAAAATGTTA TGTTAGGATGCAAGAAACCTGTGCAACATGGTGAAACCCCATCTCCACAAAAAAATTTAA AAATTAGCCAGGCATGGTGGCACATGCCTGTGGTCCCAGCTGCTTGGGAGGCTGAGATGA GTGGATCACTTAAGCCCAGGAGGTCGAGGCTGCAGTGAGCTGTGATTGCACCACCGCATT CCAGCCTGGGTGATGGAGAAAGACCCTGTGTCAAGTAATACAATTAAGTAAATAAATAAA TAAATAAATAAATAAATAGGCTACAAGAGAAAATCTTTGCCATAGAGAAAAAGAATAGAA ATTGTGTTATATTGCCTAATGATAGTACCATATTAATAGGCTTCATAAAAAAGAAGAGTA TTGGTTAAAATAATGCACTATTGGGGAAGAAAAGTAGGAAAGTTGGAGTAAAAAATACAG AAACATCATACTATATGACTTTCAATAACTGAAAAATGAAATGGAAAAATAAAAAGACAG GGGGAAGAGGAATAAGAAAGAGAAATCCAAACAAATATAATCAAGAGTTTATTTGGGTCT TAAAATATCTATTTTTTCCCTCCTGCAGGAATTTTGAATGCTATATTAGGTTTCACTGAA TTACATAATAGAAGATGTGCACATCAAAGGTTAATGGAGCAAAATGTAACAAAGAAACAA AACAAAAACAAAAACAAAATATCCTAGAGGTATTCTCTTGACTCTGACACTTAATATTCA CTCTCCTTACCACATTTGCTGCTGCCCCTCGGGGTCCATCCCGGTGAACGGCTCATCTAG AAGCACCACTGATGGGTTCCCCAGGATGCTCAGCACAAAGCACAGCTGCAATGCAAGGAA CAGCCCGTCGGCACCCAGCCATGGGTGCACAGGGAAACCCCGAGCCTGGCCCATACCTTT CTCTTTATTCCCTCTGATAGAGTTTTCACAGGAGCCTTAAGTTGTTCCTGGAGCTTAAGA GCTTCCACCAATCTGACAAAAAACAGTGTGATTATACATGAAGTATATGGCAAATGGACC TATCTAAAACAACTGTAGGAAACTCTAAGCACTATTATTCTAGATAGTAAATTTAAGCTT CCTTAACGTTTTCATAAATGCTAAATCTTATGATTTGGTTCTTATTCAGGTATTTGAATC ATTTTATTTGCATGAAAATTTAAAGACATTGTTTATAATTTCCTTTTAATATATAATGAA GAAATGACATATTTTCCCCTTCCTCCTGCTACAAATTGTGAGACTTCTCTCTGTACCGTG AAATACTGAGAGCAGCATCTTCTTTGCCCAGTCCTTTCACAGCTGCATACAACTCCAAGT GCTCTTTCATTGTAAGCTTGGGCCACAGTGAGTTCTCCTGAGGGCAGTACCCCAAGAACT TGAGGCTGTTGTCATGCTGTTGCCTTACTGATGCTCTGCTGCCTTGTAACACCACCTGCA CAAGACAATGAATGTCAGATTCACCTTTGGTTTTTGCTCCAATCCCCCTTCTACTAAAGG AGATAAAAGTGGCCATTAAGCTACAATATTTTTTGAATACGCAAGAGAAATTTTATAAAT TCTTTCATCTATTTTTTAAAAAGATATTTGATTTACTGATAGGAATAATAGAAAGATGTC ATCAATATTTAAAATAAAATTTCCTTCACATGTCACATACCACTCCTGCAGTTGGCTTTG TGCACCCAGTTATCATTTTAATGGAAGTACTTTTACCAGCTCCATTGTGTCCTAGTAATC CCAAAACTTCACCTGGAAGAAAGAGTCACCATCAATATTTGAATTTTCAAGGTTGACTAA TCTAAAATTGCTTGGTTGGTTGCATAACATTTTGAAACAAAATGACTTTTTTTTTTTTTT TTTTTTCAGAGACAGAGTTTTGCTCTGTTGCCTAGGCTGGACTGTGGTGGTGTAATCATT GCCTGCTGCAGCCTTGATCTCCTGGGCTCAAGCGATCTTCCTGCATCAGTCTCCCAGGTA GCCAGAACTACATGCATGCACCACCACACCCAGCTAATTTTTAAATTTTTTGTAGAGATG GAGTCTTGCTATGTTGCCCAGGCTGGTCTCGAAATCCTGGCCTCAAGCCTCCCGCCTCAG CCTCTCAAAGTATTAGGATTAGAGGCACGAGCCACCGTGGCCACCTCAAAATAACATTTC TGAAACAAATGCTTAGTTAGCACCTTGAAAAATCTCCTGTATTACAACATTAATACAGAG AATCAGGGTCTTCTTAATCCAAGACTGGGTTTCTTGCCATTTGAATTGGGACATGATTTT GAAGTAGAAAAGACTTATCTGCTGACATGTGAAGAAGTTTTATAATTACACATTAACCAG GATATATGAACAGTCTCAATGAATAAAAATTTGTCCCCTTTGTAGTCTTAAATCTAGAGA ATAAGGAACATTATAATAATAATAAAAGGAACAATTGTTCAAACCTTTTTTAACACAAAA GGAAACATTTCTGATGGCTATTTTCTTCTTTCTTGTTGAAAAGCAACTTTTCTTTGTCTC ATAATATTCCTTGTGTAAACAGCTTGCAGTTATGACTGGTTCCTGGAAAACATGACAAAG CATGATTTCCCTGTTAAATTTCAGATACTTTACGAATTGATGTTTTATTTTCCATTCCCT AGTCTATAAACCCAACTAAATTTAATGCCAGGCTGAAGAGCTTTAGCCTCTTTTTTCAAA TAAAATACCCAAATGTATGTTCATAAATAAGGGCTACTTAATCAACTACTAATAAAATTA ATTCCTAATCAAATACATTCCCTTTGCATTATGCTAGCAGCTATCTTTGCCCTTTCAACA ATTTCATTCCCAGTTTATTCCTTATTGATTTCCATGCATTGTAAATTCATTTGCTCTTGT TCATATGCTATTCAGTTATTAATATTACAAGCATACTATAATATAAAATGTAATTGCAAC TCTTGAAAAATGTGCGATTTTGCTAAAATTGATTAAAAAATTCGAGAACTTGTTGATTAC ACTGATGAATGAGGAGCTGGAAGAGTAAGACCCACAGAAAACTGAAGAAGAAAAAATTAA AAGAATGAGGACAGGGTAGTTACTTTTAAAGAGAATAATTTGAATATAAGCTATAAATAG AAATATTAAAGAAACTAAAGCAGCTTTTCAAAATAAAAACCAACATCTCATCAATTCTAG AGGACAAACTATCTGAGCATTTTATTAAGGGTCTAATCCCTGCTGTTCACCTCCTCCAAG TTTGGAGCAGTGAGTGCATTTGCTGCTTGGACTCTTTCAGCTTGAACATCTTCATCTTCT TCTTCGGGCTCTTCCGGATTGGGATGAGTTTCTCTACTCCGTGGAGAGATTCTACAGAGG AAATAAAATAACATAAAAATGCAATTTTGGCTGTACAACTGTTAAGAAAATGTAAACCCC TATAATTAAATTATTATCCTTTTTAAAAAAGACTATCACATCATTAATTTATTACCTACA AGATTCTTCTTGGCAGTAATAACACCTCCGGTAGCCAAGTCCCTTGAAATATTCTTTGAC TATTTCTTCTCTTTAAAACATTGTATCCTATCTGTCAACTGGCTCTGTCACTTCGTTCTT TTAAATCACTCAAATGTAGACATACGGGTCTTTTAGTCTGTCACCATCCAGATCATGACC ACATTCCTCATAAAAGATCATCCTAACTGGTTTTATATGGAACCAGTTTTTACTGTACCT TCTCCTTAGGGACCCATAATGGCCACAACCAGGAGAAAAGCAAGCTTTGATGCTTAAACA CTACTTACAGACATGTACAGGACAAAAACTTATCTTGCCTAAAATCAGAACCTATGACTT AGAAACTATCCCTGCATCCAATCTAATTCTGTTTTCTTTTTCTGAAAATAGCACTGTGCA ATATGCTTAGCCAAGTGTTGGGTAGTAAATCCATTTTAATAAACTGATGTTAAATGTACT GCAATAAAGACTAAATATTTAAGATCACAACAGGAGGATTACTTGAGGTCAGGGGTTTGA GACCAATCTGAGCAATATAGCAAGATCCTGTCTCTATTTTCAAAAATAAAAACAAATAAA ATTATAAATTTAAGAAGATTAAATATTTAAATTACATTCAGATCTCAATTAGTATTCTCC CAACCTGAAACCCTGTTTCTATTTTCAAAAACAAAAACAAATAAATAAATGAAATTATAA ATTTAAAAAGACTAAATATTTAGATTATATTCAGATCTCAATTAATATTTTCCCAACCTG AAAACTGGGTCTTTATTCATTATTTCATTTCCATACTTCATTTCCAGACACCTTATGACA AAAAGGAAAATAACACTCTGAAGGTATGGCTAAAAGAAAAGAAAAATAATCAGAATTAGC ATCACCATGGCATTCACACTCAATGGTGAATATTTGTCCATTTTTTTGTCACAGAAGATT TGATCATTTTCTTGAAGATTTGATCATTTTCTTTTAAATTTGACAAGCAACTTGTAAAAT ACTTCTCATGTGGAAGAAAGGTTTATTCAAACTCACCCTCCCACTGAGAAAGAATTAAAA AGCCCACATTAATTTTTTTAAAAACTTTTAAAAAGCATAGAAGAGCTAATAAAATAGTAT GGGCTTTTAAAGCCAAATCTAAATGAATACAGGAGATAGGTTTAGCCCCAAAGCAACTCT TGTCCTAGAGTTATTCTTTATCCTTGAAATACTCAAACTTCCGTTTTCATGCCATGTCCA GGAGCAGAAGACAGAAGAAACTGTTGAAGCAGAGAGTCTTCCCCAAGTAAGGGGTAGATA GGTCACTCTTTCTCTAATAAAGGATGGACCTCAAAGGGTTATATTTTTAGTGAGGGGTGA AAAGAACCCTCAGGATATTGCTAACATCATTGCCTTGAGTGCTCATCATGGAAGGAGAAA GTGAAGGTGGAAATACAAGCCAGCTTTTACACAGACTTGGAGCCCAAATTCACATCGCTG GATGGTCAAAACAAAACCTCAAGCCTAGGACATGGTTTAACATGGTACCAGACTGGTAGT GTCCCTGTGAACTTGACAGAAGCAAACAAAATGTAATAGTTATCCCAGAAACAGACTCTA CATATATAGGCAACTGATATATGAATAGAAGTAGCTCTGAATATCAATGGGAAAGGCACA GACTTTTCAAAACAGTTGTCTCAACTGCTGGGACAACTGGACATCCTTAAAGATAGAAAT AAAACAAGTCCACAGGAAAAAAAAAATGAATTTTAGATGATTGAAGACATAAATGTGAAA GGGAAATATAAATATTTTAGAAAATAATATAAAATAATATCTTCTTGACCTTAGGGAGGG GGGGATTTCTTAAACATTACAGAATATAAAATAAAATTTATTAATTTTTAATGGTTTTAT TTAAAATAAATTAATCATTCTTAACAGAGGCTCACAGGCTTTGAGAAGATTCCAGATTCA TTCTTGATAAATACTAGAAACAAACAAAAGACAAAAGCTCTCAGTAACTCAGGAATTGAG GGATTTAGTAAGATAAATAGTTTATATTTTTAAAAGTTACTATGATGATAATGGTTAAGC ACTAAGAAAATTCTCAGTAAAATCAGAAACAATGTAAGGACGCCTTCTTGCAACAGTGTT AGTGTTAGTGGATGATTTTTAGAGATTCAAGCCAATGTCATAAAGCAAGAATATATAATG CAGTATATATTTTCAAAATAAAAATATAATTATTTCATAACATGGTTGTTTCACCGGAAA ATGCAAGATAAGAATCTGAAAAAAAAATTGGAAATAAGAAAATTCAGTAAGGTAAACTGA TATAAGATAATTGTACAAGAATTTTATATTTTTGTATAGAAACCTAGCTAGAACGTGCAA TGGGAACAAAATTTTATGGCAAATAAATAAATACATAAATAAATGTAACTGAATATACAC AAAAGGGAAATAAAGTAAAAATATAAAATAAAATACTAAAGTATATAAAATAAACCTTAA ATGCAGATAAACCTTTAAACATAAATATTTTCAACTCACAAATACTGCTCTAGCAAAATA AACATTAACAATAATGTCCATAAAAGTCCACATACCAGTTTCTGGCACTTGACTGCATTC TAATTTTCATCAATAAAATTGAGTAGGAAAATAGAAAAGTTTTGAAAAATTAGGATGATA GGACATATGTATCATTTTGAATTGATCAAAATATATAAAGCTACCATAATTAAAACAATG TAGTCCTGACACTGATGTAAACAAATGGATCAATGGGGAGAATATCAACACAATCAGTCC ATAGATATAAGCAAATTTAATACTGATAAAGATGTCATTTCATGTTGGAAGACATAAAAT GGAGTATTCATAAATGGCATTGAGATAACTAAATGCCCTTTTTTGGAAAAACTTAAAATA CAAAGGTTAGTCTATATCTAAAAACAAATCATAAAATATATCCAGAAGATTAAACATTTA AGTATTTTAAGAAACAGCAAAAATTATAAAACAGGAAAGGGTGACCCACATTCAGAAAAA AAAATTAGTTAACAGAAATTGGTTTTGAGTGTTATCAAAGATGTAGAAAAGCTACTATAC ATTCACTAAACTAAATAAAGTCATATTTCAAAAATTAAAGTAAAATATGACTCAAATACA GACTTTCTATTATATAATTGATCTGAAGAACAGAAAGAAAAATGATGAGCAATAAATAAA CAGAGCCTCAAAGATTATCAAGCATACCAAATATATGTAATGGTAGTTCCAAAAAGATAG GGGAGAGAGAAAGAACAGAAAATTTTTTTTAAGAAATGATGGCCCAAAACTTCCAAAATT TGTTTTAAAAAATATTCATATACACATTCAAGGAGCTTAACAAATCATAGGTAAGATAAT TACAACAAGATCCATATCTAGACACATCAGAGTCAGATTGCTGAAAATCAAAGGCAGAGA AAACAGTAAGTGGGAGAGGATTCATCACTCAGAGAGAAGCAACAATACAATTTCTTCTCT TCAGAAACAATGGAGGCCAGGAGAAAGTGTGATGATGTAATCAAAGAACTGAAAGAAAAA AAGTATCCAAAAATTGTATATCCAGTAAAATAATTTTTCAAAATAAAATCATTCCCAAGT TGTTCCAAATTGCCTTAATGTGGCCATCATTACATTAAAAAGGGAGACAATAAAATAAAT AAATCAGCTATAAAATTTTTATTTTAAAATAGACCAATGGAATAGAATAGAAAACCCAGA AATAAACCCTCCCATATATGCTCAAATAATCTTCAACAAGGGTGCCAAGACCACTCAATG TGAAAAAGACAATCTCTTCAACAAATAGTGCTAAGAAAACTGATGTCAATATGTAAAAGA ATGAAGTGGAGGCCTTATATTATACACAAAATTAACTCAAAATGGATCAAAGACCTAAAT GGAAGACCTAAAACTATAAAACTCATAGAAAAAAACTTAATAAAATTGGACTAGACAGCG ATTTATTCAATACGACACTAAAAACACAAACAACAAAACCAAAAATAGACAAATGTGTTT GCATCAAATTAAAATATTCTGTGCATCAAAGGACACAACTGACATGGTGAAAAGATAACC TACAGAATACAAGAAAACATTTTCAAATCATATATCTGATAAGGAGTTAATATTCAGAAT ATATTTTTAAAACTCCTACAACTCAATAACAACAAAAATTCAAATAACCCAATTTAAAAA TGGGCAAATAATGGCCGGGCACGGTGGCTCACGCCTGCAATCCCAGCACTTTGGGAGGCT GAGGCAGGTGAATCATGAGGTCAGGAGATTGAGACCATCCTGGCCAACATGGTGAAACCC CCTCTCTACTAAAAATACAACAATTAGCTAAGTGTGGTAGCATGCACCCATAGTCCCAGC TATTCAGGAGGCTGAAGCAGGAGAATCACTTGAACCCAAGAGGCGGAGGTTGCAGAGAGC CGAGATTGCACCACTGCACTCCAGCCTGGTGACAGAGCAAGACTCCAGAAAAACAAACAA ACAAACAAAAAAACCAAATAACTTGAATAAATATTTCTCCAAAGAAGATATATAAATGGC CAACATTAAATGTCAATGAAACGCAAATGAAAACCACAATGGCATACCACCTCACATCCA TTAGGATGACTACTATATAAAAAAATAAGTGTTGGTAAGGATGTGGAGAAATTGGAACTC TTGTACACTGTTGGTGAGACTGCAAAATGGTGCAATTTCTATGGAAAACAGTATGGAGGT TCCTCAAAAAATAAAACTAGAACTACCATATAATTCAGCACTCCCACTTCTGGGTATTTA TCCAGAAGAACTGAAAGTAGCATCTTGAAGAGAGATTAACACACCCAAGTTCATAGCTTA CAATAGCCAAGAGGTAGAAGTAATGCAAATGTTTATTGACAGAATGAATAGATTTTTTAA ATTATGGTATATACATATAATTCAATATTATTCAACCTTAAAAAGGAGTGAAATCTTGAC ATATGTCTCAACATGGATAAACCTTGAGAACATTATACAGAGTGAAATAAGCTAGTCACA AAAAGACAGATACTTTATGATTTCATGTATATAAGATATATAAAGTAGTAAAATTTATAG AAGCAGAAAGTAGAATGGTGATTACCGGTTTGGGCAAAGGGGAAAAGGGAAATTGTTTAA TGGCTATACAGTTTCAGATTTACAAGATTAAAAGTTCTGGAGATTCTTCTCACAACATTG TAAATATGCTTAAAAAACTGAACTATATATTTAAAAATCATAAGGATGGTAAATTTTATG TTACGTGTCTTTTTATTACAATTTGAAAAGCTGAAAAAACTTATATGTGAAAAATAATTG CAGTTGTTTTTACCACCACAGGTCACTGACTAGAAACAAATAGGTAAATAGCCATGAAGT ATAATGTGGTGGGATGTGACGAAAGCCGCTTCTAGGCCTGGCCGTTAAAACAAGGGGACT TCAAAAATACCATGAAAAATTCATATGATGAAAAACCTATGTGTGGATTTCAAATTTGGG GGGCAACAAAATAAACTCATCCTAACTTCTTATAATATGTTTGAACAGGATCTGGTTTGA GGTACTAAGAAGGGTACATTCATTTGAAAATAGGTACATTCATTTGAAAAGAGCCCCTAT CAGAACATGAATTCTGCTAAAACTGAAGCAAGAACAAACATCAAGTGTATGGAGAAGCTT GGAAGGAAGAATGGTGAAATCATCGATGCTGTAAAAAAGTTTATGAGGGCAATGGCCCAA AGAAATTAGCAACTTACAGATGGTTAAGTGGTTTTAAGAAGGAACAAGACAATGTTGAAA ATAAGTCCTATAGCAGCAGACCATCCACATCAATTTGAGAGGAAAAAATTCATCTCTTTC ATCTCCTAATTGAAGAGGACTGACAATTAACAGCAGAAACAATAGTCAAATCACAGACAT CTCAACTGATTCAATTCACATAATTCCGATTGAAAAATTAAAGTTAATCAAACTTTCTAC TTAGTGCAGGACAAAACTGTTGTGCCCAGGTTAGCAGAAGACAAGAGCAGAGCATTCAAT GGAGATTTTAAACACATGGGATCGAGATTCTGAAGCAATTTTTTTGAATAACTGTTTACA GGAAATAAAACATGGCTTTACCAGTATGATTCTGAAGACAAATCACAATCAAAACAATGG CTACCAAAAGGTAGAAGTGGGTCCAGTTAAAGCAAAAGTGAATTAGTCAACAGCAAAGGT CATGGGCAACAGTTTTTTGGATGCTCAGGGCATTTTGTTTGTTGACTTTCTGGAGGGACA AAGAATGATAACATCTGCTTATTATGAGAGTGTTTTGAGAAAGTTAGACAAACATCCAGG AAATCTTTACTAGAAGGTCCTTCTCCATCATGGCAATGTTCCTGCTCATTTCTCTCATCA AACAAGGGCAATTCTGTGAGAGTTCCTTTGGGAAATTATTGAGGGGTATCCACCTACAGT TCTGATTTGGCTCCTTCTGAATTCTTTTTGTTTCCTAATCTTAAAATATATGTAAATGGC ACCCATTTTTGTTCAGTTAGTAACGTAAAAGATACTTCAATGACAAGGTTAAATTCCCAG GATCCTCAGTTCTGTAGGAATGAACTAAATGATTGGTATCGTTGCTTACAAAAGTGTCCT CACTTTGATGGGGTTTATGTTGAAAAAATTACATATATACATATACATATACATATACAT ATACATATATATATATATATATGAGACGGAGTCTCTCTCTGTTGCCCAGGCTGGAGTGCA ATGGCACAATCTCAGCTCACTGCAACCTCCATCTCCTGGCTCAATCGATTCTCCTGCCTC AGCCTCCCGAGTAGCTGGAATTACAGGCACATGCCAGCACGCCCAGCTAATTTTTGTATT TTTGTAGAGATGCGGTTTCACCATGTTGCCCAGGCTGGTCTTGAATTCCTGACCTCAGGT GGTCCACCCACCTCGGCTTCCCAAAGCGCTGGGATTACAGGCGTGAGTCACTGCGCCTGG CCAAAATTTATATTTTTTTATTTTCAACTTTTAGTTCCATTTTCCCATGAGGATTTTGGA GTCCCATCTTGTCTAATGTTCTAACCTTTTCTTCCACTGCAAAGGCAACCCTGAAGATTG AGGGGTGTCAAAAAGCACAGCCACCAAATGGAGGTGCGCAGCCAAATACACAATAGAATT TATTTGAAAAATAAATCCCTATTAAGTCTTGAAGGTTCCAGGGTTTGTTTGCTGTGTCAG AGTTGCAATGAACATATATTCCCCAGCTGGACAACTGTATGCCTTTAGAATTCAATGGTC AATTAAAAATGACTATATATGGAACATCTCTGCATGTATTTACAAAACAGGAAAAATATA CATTCATTATACAAAGACCCAGGTAAAAATGTATAAAAGTTTATAAATCAAAACAAATTT AGAGGTTTCTTCCTTGATAAACTGCTGTTCTGCTATTAAAGAGGAAACAAGAGGTGTGCA AACAAGAGTATGTTTCCTCCTTCTGCCTCATTTGCCATAATACACAGAAATAACATTTAT ATTCGCTTTCATTGTCTTTCCCCACTATAAAATTTCATTTAATCTTTCTCCTTTCCTCCT CATTATTCAAATTAGTTGTTATTAACACATATTTACTTGATTCTGAGCCATACACCATAT GCTGCATTTCTTACATACTGCCTCAAATTGTCTTTGGATACATATCAACAATGTCTATCA CAATAACAGCAACCAAACCTTTAAATGTTCTAGTATGTATTATATTATCTGTGAATCTAT TTTAAAAATATCTTTAGTTCTTGCTGCCATTATATTGGAATGGAAAATACAGAAAGAGTG GGTATTTTAAGACATTTAAATTTGGCATACCTTGAATAAGATTTCACGGGGCTATGAATC TTATGCAATATATATATTTAGGTAGAAAATGTTCCTTACTATTAAGGTTGTTAAAAGAAT GGTTTTATTGACTTCATTTATTCTATTGTCCAGACTGTCCAAGTTTCTCATAAAGTCGAG CTGAAAAAAAACCCACCAACAGTTAAATGCAAGTTTCTCTATAAATATAAAATTTACACA TTAAATACACCCACATTATACTTGATGTTCTATGGGACAACAGTAAGTATTCCATGAATT GAGATGAGAAGAGTTGTTTTCTGATGCTAAAGTCTACTGATGACCTGACATCTTTCCTTA GTTATGAACTCCAACACTGTTTATTTTCCAATTGTATGTAATAGGGATTTCCAAGTTTCT CTTTAGTGGGAGTGACAAAGTACAGAACTATGAAGTAGGCAAGATTTGCCCACAGTTCCC CAAAATTCTCAGTGGTATTTAGTTTCTGTCAGAAGTGGTTAATAGAATCATGTTTTCTTT CCCTCACTCACAAGTCATACACTCCAAAAGCAATTTATTGACACTAAGTAGTATGCAATC AATAAGTCCAATAAGATTTTAGACATTGATCAACATTGAAATGAAAAACTTCTATCCCCT GGCAAGATGGATTCACCACAAGAGAGCATGTTTTATAACAATGGAAAAGTTTTAGTCCTG TCTCAGAATCACCTCTGGAATTCATAAACCACGGTTGGGCTTCCTGCTGTATTTCTGCAT GGATTGACCCTCTTCCTGCTAGTATGAATAGTGATCTCAGCAAATTTGACAGCTTTCAAT TTTATACAGCTTTAAAATCTTATTTTTAGAATTTATCAGCATTGAATAACTTCAAAATTT TATAAATGCACCTGTTCCGACAATGGGTAAGGATTTTATTAATGGGCTACAAGGTCAAGA CTGGAGACACAGTAGGTAACACTGCTTACCTGGATCAATAACATGACATACCCCAGCAAA GTGAAGGAAGGTATGAAAATCATGCACAAAATTAAGTTGAGTTTTTCATATTGAGTTGAT ACCATAATTGTGGATACACATATTAAGATCTAGAAAAAAATCCAGAAGTATTATAATTTT CTCAGTTATATTTGATATCTTAAGATATTTCCTGTGAATAACCTGTTTTCCTGGGAGATA CTGCCATTTTCAACTTTTACCTCACAGATAGAAATATTCTTAGGATATCCTCTTTAGGAA GTCTCAAACTTTCACTGCAACTAAAACATAGGATTACAATAAGGTCTGTCATAAATACCT TAAAGATTTTGCAATACCCAGTAGGGATAAACAGCAACAATAAAAGAAGGTGATGTAACA TTATTTATTTTGTCTATTATAATAAATCTTAATATGTTTTCAGTACAAGGATACAGTGAA GAATTAACTGATGATATGACTTGGGAACTTAAAAGGCAAAATAAACTTTGAGGTTGGTGT TTATTGCCATATCTAAGCAGTCAGAGAAATGTAAGAATTATCAGTCTTGATATCCAAGGT AGGAATATTGAACAGTTTAGAACATTCCCAGAGGTAAATTATATGGTTGTCACTTTAAAG GGCAGCCCATATCCCCACTCAGACTGTTAGTCGTTTCCTAAAATGGCTCCCTGGCTCCAG TTCTTCTGCCATTCAAAATTCATATGACATTCCAAAGAGTATATACAGTTAACTCTTGAA TAACATTAGTTTATTGTAGGTGGATTTTTTTCAATAAATATGTTAGAAATTTGGGGGAAG ATTTGTGACAATTTGAAAACCTCACAGATGAACCACATTGTCTAGACATATTGAAAAAAA TTAAAGAAAAATTAGGTATATCATGAATGCATAAAATATATGTAGATATTAGTCTATTTT GTCATTTACCACTGTAAACTATAAACAAATCTATTATGAAAAGTTAAACTATATCAAAAC ATGCATAGAAACTCTTACATACCATACATGTTGCCATTAGCAATCAAGAAAAATGTAAAC ATAAAGATGCAGAATTAAATCATGACTGCATAAAATTAACTGTAGAACACACTGTACTAC TGTAATAATTTTGTAGTCACCTCATGTTGCTACTGTGATGAGCTCAAGTGTTGTAAATAT TCCCTTAAAATGCTGTGTGAGGCTAATCATCTTATTCTCAAGCAAATGGCATATCTCAGT AAAAAGTGGCTTCTCATGGTTCTTGCAGATCTTTCATTGTGTTTAGTGCAATACCATAAA CTTTGAATAATACCGTAGGACCTAGGAATTGCCACTAGTGATTCCAGAAGTTCTCCCAAG AAGCAGAGAAAAGTCATGAGATTACAAAAAAAAAAAAGGTTGAATTGCTTGATATGTACC ATAGATTGGGGTCTGCAGTTGCAGTTGCCTGCCATTTCAAAATAAATAAATCCAGTGTAA GGACCATTGTAAAATAAGAAAAGGATATTTATGCATCTGTCACTGTAGCCACACCAGCAG GCACAAAAACCTTGCACTTTTTTTGAAATACTTTGAAATCTCACATTGATGATCCAACTT TTATACCTATAGGCTTTAATACAATTTGAGAAAAAGTGAAGTCATTATATGACAACTTAA ATAAAAGGTTAAAGATCTAAGGCTGGAGAATGTAATGCCCTCAAAGGATGCTTTGTTAAT TTTAGAAAGAGGTTTAACTTAAAAAATGTCAAGATAACAGAGAAAGCAGCTTCCGCCAAT CAAGAGGCAGCAGACAAGCTCCCAGATGCTATTAATAAAATCATTGAAGAGTAAGTGTAT CTGCCTGAACGCATTTTTAATACAGATGGAAGTGCCCTCCCTATTCTGGGGGGAAAAGTG CCACAAAGGACACTGATTAGTAGAAAACAGAATCAAGCACCAGGATTTAACGTAGAAAAG GATAGGCTATTTGTGCAAATGCAGTTGGGTTGATGATCAGTACTGCCATTATCTATAAAA GCTGATAACACTCAAGACTTGAAGGGAAAAGATAAACACCAATTGCCAGTCTTTTGGTTA TACAACAAGAAGGCCTGGACAATGAGAACCCTTTTTCTGGATTAGTTCCATGGATGCTTT GTCCCTAAAGTCAGCAAGTATCTTGCCAGTAAGGAACTGCCTTTTAAAGTTATTTTGCTA CTGGACAGCACCCTTGCTAACCCAGAACCATGTGAGTTCAACACTGACGGCAACAAAGCG GTCTGCTTGCTCCCAAACACATCTCTAATCCAACCTCTAGATCAGGGGTCATAAGAACTT TTCAGGCTCATTACACACAGTACTCTATGGAAAGGATTGTCAACATCATAGAAGAGAACC CAATAGAGAGAACATCATGAAAGTCTGGAAGGATTCCACCATTGGAGATGCCATTGTTAT AGAAAGAGCTGTGAAAGCCATCAAGCATGAAACAATAAATTGCTGCTGAAGAAAATTGTG TCCAGATGTTGTGCATGACTTCACAGGATTTACAATAGAACTAAACACAGAAATAAAAAA GAGATTGTAGACAGGGCAAATAGGGTGGGGAGTGAAGGGTTTCAAGACCTGGATCTTGGA GAAATTCAATAACTAATAGACACCACACCAGAGAAATTAACACAAGACAATTTGATGGAA AGGAGGGTTTCCATTGCCAGATGATGAGAAAGAAGATGTAGAAGAAGCAGTGCCAGAAAA AGAATTGACATTAGACAATCTGAAAGAAGGATTCTGATTATTCAAGGCTCCTTTTGACTT ATTTTATGACATGGAATCTTCTATGATACAGGCACTGAAACAAAAGCAAACAGAGGGAAA AGGATTGGAGCTATATGGAGATATTTTTGGAGAAATAAAAAAGCAAAAAGTAAGACAGAA ATTATAATATATTTCTGTAAAGTTACACCATGTGTGTCTGTCTCTCCCGCCTCCCCTTCC ACCTCTTCCACCTCTTTCACCTCTGACACCCCTAAGACAGCAAGACCAACTCCTGCTCTA CCTTCTCTTCCTTCTTGGCCTACTTAATATGAAGACAACAAGAATGAAGACCAAGAATGA TAATCCACCTCTACTTAATGAATAGTAAATATATCTTTCTTATGACTTTCTTAATAACAT TTTCTTTTCTCTAGCTTACTTTATTGTGAGAATACAGTATATAATATATATATACAAAAT ACACGTTAAGCAACTATGTTATCAGTAAGATTTCAGTCAACAATAGGCTATGAGTAGTTA AGTTTTAGAGAGTCAAAAGTTACACATGAATTTTCAATTGCATGAGGGTAGGGGGTTGGT GCCTCTTACTCCGACGTTGTTCAAGGGTCAAATATATTTTGATTTGAACAGGAATCATTC TCTTTTATATTCCATTGAATTTAAGTCCTCTGATTGCAGAAAATTTGCTTTGTTCATGGT TATATCCCAAGCAAAGTATCTGGCACATAGGAAGATACAATCAATATGAATGAATGAATA AATATTGGGAAGGGCAAACAATAAGGAGGATTTCTATTTCTCTGTTTTTATTCACCAAAT AATCAAAAAATATGCATATTAACAGTGCAGTTGATACAAAACACTTTGTTAAATAGTTAC TGTAGTTACAGGAATAAAATTGGAGGAAGAAAAGGAAGATTACACGGTTTGGCTCTGTCT CCCAACCAAATCTCATCTTGTAGCTCCCATAATTCCCATGTGTTGTGGAAGGGACCCAGT GGGAGATGACTGAGTTATGATGGCAGGTCTTTCCTGTGCTGTTCTCATGATAGTGGATGG GACCAACAAGATCTGATGGTTTTCAAAACAGGAGTTGCCCTGCACAAGCTCTCTCTTTGC CTACTGCCATCCATGTAAGATGTGACTTGATCCTCCTTGCCTTCTGCCATGATTGTGAGG CTTCCCCAGCCACATGGAACTGTGAGTTCTCCATTAAGCCTCTTTGTAATCTTGGGTATA TCTTTATCAGCAGTGTGAAAACAGACTAATACAGAAGAAGAGGATAATAATTCCTATTGA GTACTTCATGAACATTTACTATTTATCAGATATTTTAATGAGCAGTTTACCAGCACTATA ATAGTTTATGCTCTTTTAAAATCTCAATCCTAAAACACTAGAAAGTACTACTGTTATTAT ACATATATTCTGATGTTTAAATAACTGAACCTCAAAAGAACTGAAATAATGTGTTCAATT TCTTATAGCTACTAAGTGCCAGACCACTGAGGATTAAAACCTGGGGCTATCTAACTCTAG AGCCAAAATTCTTAATCATTATACTTTCCTAAGGGATATTGTATCAGTCAACTGTCCATA CATCAAGTCAATATATAATGTACTGGATACCATGAACTTATATATACAAAACAGATGTTT CTAAAAGCCTAAAACAGAGAAGCAGACATTTGTGAACTGGAAGATTCACTATGTAAAGAT ATCATTTCTCCCCCAAAGTAATTTATAGATTCAATGCAATCCCAATTAATATCACTTCTT GTGGAATTTGACAAGAAGATTCTAAAAAGTGCACGCAAATGCAAAGAATCAAAAACAGCC AAGATACTTAAAAAAGAACAAGGTGGGAAGGTTTGCTCTCTCAAATAAAGCTACCATAAT TGAGACAGCATGGTATTGATGTACAAATAGAAAAACAGATTAATGGAAGAAATCAGAAAG GCCAGGAATAGTCTTGATTGATAACAAAGGTAGCACTGCAAAGCAGTGAGATAATGATAT GGACAAGTGGATATATAAATATGATACGTATCAAAAAGGCATATAAACAGTGTTTCTTCC GTATGTACAAGAAAAATTTTCTGAAGGAATAAACAATATAAACTGAAATAAGCTCAGGGT TTCATCAGCTTATTTTATAAACATTGTGTATACTTCAGAATCTCCTCAAAGATTTCGTGG CCATAGTATTTGTAATTATTAAAGGTATTGCTCTAACAAAATATATAGCAATATATCTTC AGTATTCTATAAAAATTAAGTTGGATTTTCTGGCCGGGCACGGTGGTTCAATCCTGTAAT CCTAACACTTTGGGAGGCCAAGGTAGGCGGGTCACCTGAGGTCAGGAGTTCAAGACCAGC CTGGCCAAGATGGTGAAACTCTGTCTTTATTAAAAATAAAAAATTTAGCTGGGCATGGTG GCGCACACCTGTAGTCCCAGCTACTCAGGAAGCTGAGGCAGGAGAATCACTTGAACCCGC GAGGTGAAGGTTGCAGTGAGCCAAGATCGCCCCACTGCACTCCAGCCTGGGCAACAGAGT GAGATTCCGTCTCAAAAAAAAAAAAAAAATTACGTTACATTTTGTAAATCTAACAATGCA AGTGAAGAATGTATCTTTGACCATCTTGCTTCTTTCACCTTTATTCCATTCCTTTTTGTC TTCTTACTACACTAATTACCACATCTATATTGTTTTACTCATCAAAAAAAAAAAAAAAAA AAAGAAGTCTTCCATTAACCATTCCTTCTGGCAAGCAATGATAGCAACAACAATGCCTTG TAAGGAGTAATTAAACACTTCCTGTTTCTGCTTCTGCATTCTATATTTATTCTTCCATCT GCTACAAACTGTATTCTGCATTCACTGCTTTATAAAACTGCAGTCTCAAAGTTAGTTGTA GACATCTGTATGTAGAGATATGATGTAACAGATACCCTAAAGGGTCTTACCCATACTGTA CAATTAAATTTTGGGAAATTGAAACAACTGTCCCTTACATACACTGCTAGTTTCAAGGGA AAAAAAAAAAGTGAGGAAATTCTTCAAGGACAAAAACAAAGCCTGAAACCCACCTTGGAC CATTAAGTAAACACAAAATCTGCTTGGGCTGAGGACAAGTCCCCATATCAGCCCATGAGT TAGGAAGATATGATTTGGGTTCTCTTTAAAGTCATTCCCTGCAAAGACCTTTAAGAGACT AAAATGAAACCCTCTTGATGGGAATTCCTTGTAAATCCCATATTGAGGCATGATACTCTA AGTTGGCTTGTACAATCGTAGATGGATTCTACACTGCATGTCTCACAAAAGTAAGTGAAA ATCTTTTGGGGATGAAAACATCCCTAATACAGAGTCTTCGGAGTTCCACACTTTAAGGTC AACCAAGTATGAGCTCCTCTCCCCGACAAAAACTTATCAAACATATAAGGCAATAAGCAC TAGATGACTTTTGAGACTAGAATTGTCAAACGACAAGTAGAAATGTTGTTTTCAATGAAA TGTTGAAATAAATCAAATATGAAATATAGAACAATAACAAGTAACAAAAGATTAGGAGAA ATAACTAAGCATATTTTAAATAGAACCAAAAAGAGTTTTGGAAAACAAAATTGAAATTTT AAGTAGTCAATGAGTAAAAATAATTTAGATGCAGATGAATTTAAAACAAGTGAATTGGAA GAAACGTCTGAAGCTTCCCCAGAAGGCAGCAAGGACAAGGACATGGAAAATTTGAATGAA ATGCTAACAGATGTAGAGAATAGTATGAAAAGCTAATATTATCTCAGTAGAGACTTTAAG TCAGACAGGCAATATCTGAAGTGGTATTGGCTGAGAATTTTCCTAAACTGAAGACAGAAA TGAATTCCAGGCATCCCAATTTATACAAAAATAAAGATAAATAGAAAATCACACCTAGAA ACATTGTAATGAAAGCTAAAGTCAGAGAAGGTTAGTCAATGAGAGAGCCTCTGCAAAGGA TAGCAACTGACTGATAGCAGACATCTGAACAGTTAAAATGTAAGCAACAAGAGAGTGAAT TTTCAAAGTGATAAGAGAAAATGACTGTCAACCTAGAAATGCATAAGCAGCTAAATTATG TTTTAAGAATGAGGGTGAAAAAAGATTTTTTTTAAACTACGAGAGTTTATAGCTAACTGA CCTGTTAAAGGAATATATAAATGATGCATTTTGGGAAGCCAAAAAAAAAAAAAAAAAAAG ATTGATCTCAAAAGGGAGGAAAAAAAGACTAAAATCCAAGTATGAATAGTGAACAAATAG ATTGATTTAAAATGTACACAAATCTTTTTTAAGTTCTTAAAATGTTAATAAAAATGCTTA TTTGAGGGATTAAAAAAAGAAAACCAAAACACTAGACAATAGCATGTAAGTAGGGTAAGA AATTATTAATAATAAAATCCTCAAAATATGGTGTTGGAAGTAATTAAGATATTTATTAAC TTTAGGCTTTGTTAAGTTTAGCACATAAAAAATTTTTCAGGGGTGTTATGGGCTGAATTT TGCCTCCCCAAAATATATATGTTTAAATTTTAACCCCCAGTAGCTCAGAACATGACTATA TTTAGAAATAGTCTCTAAATGGGTAATTAAGTTTAAAGGATGCCATTGCAGGAGTCCCTA ACCCAATGTGACTATTGTCCTTATAAGAAGGGGAGATTAGGACACAGACGCGTCCAAAGG GAAGACCATGAGAAGACCTGGAAGAAGATGGCCCTCTATAAGCCAATGGGAGAGGCCTCA GAAGAAATCAACCTTGCCAATAGCTTGACCGTGGACTTCTGACCTCTAGAATTGTGAGAA AATAATTCTGTTCCTTAAGCCTCCCAGTCTGTAGTACTTTATTATGGCAGCCCTAGCAAA TTAATACAAAGTAATAAAATATAGATTATGACTTTCAAACCAAAAAAAAGAAAAATATGG AATAAAAACAAATTCAAACAAACAAAAAAGGGAAGAAAAAAGAGAAATCACATACACAAA GCAAAAAGTAAAATAGTGTAACTTCAAGAATATCAAAAATCACAATAAACTCATTAAATT AAAAGCAGGTTAAGTCTGAATTAAAAAACAAATAAAATCCAACTATATTTCTTTTACAAG AGACAGGCATTAAAGCATAAGAACAATAAAAGTTAAAAGTAAACACAAGTGGCAAAAAAG ATTTATCAAGCAAATACTGAACAAAAGAAATCTGGTGTACCTATATTAATATGAGACACA TTTGACTTTATGGCCAAAAACCATAAGAATAAATAGGGCTGGTGTATAATCATTCCAGAC TTCAATGCACCAAACAAAATAGTTTCAAACTATACAAAGCAAAATTGGATTAAATTAAAA AGTGAAACTGACAAGCCTACCTTTACAATGGAATTAGAAGAGAAAAAAATAAAGATCAAT GACTAATGCCGATGGTTAAGAAGACATTACCCTTGGTTATGATATTTGACCATTGTAGTA CAACCATTGATAAAACTGGCCCAAGGAATTATGTGATTAGCTGTCACAGGGATGCGATTT GGAAGCTTAGAAGCAATTTAGTAGCCTTTAGGATTTCTGCTGACATACTGAATTCTCCAA CTGGTTGTGTTTGTGATATTCCTGCTTATACTAAATCCAACTTTTAAATACTACTCACAA AGGCCAACCAATGTAACTGTAACAGCTCCAGTGAAGTAAAACTTTGGTCCTTTTACCCTA ATCCCTTCACCCTGTCCACAGAAAGAGAAAGGAAAATCCAGAAGAAGAAGAAGAAAAAAA GAGAGAGTCAAAGTGTAGACCTTGCTCTCTTTCTCACCGCTGATCCCCAAACTAAGGGCG TGCCTAAGATGAGCCTGGGGAGAGAGTTTTACATTGCTTAAGAAAGTTATGATTTGGACT TGACCAACCTTTTAGATTTTTTTTAGTTCTTTAAGTGAATCTTACTTAACAAAATTGGAC TGTTTTAATGTTTGAAATGGTCAGAAAGCTATAGTAACTGCTTAAGATATCAGCTAGTGA TAGGGAAGGAGATGCAGTAGCATATGCCTGAAGTAATAAGTAAATTATTTATTAAGAAAA CAGTTTCTTATTTATTTTATTCATCTATATAGCCCCCTATCATGCTTGTTGTTTGTTTGT TTTTTAAGGAAGGAGAATTATTTAAGAGAAAAACATCACTGAGTTGAGAGGCCTGCGTTT AAGTCTGATTCTTTTCAGTTTTTCCCACTCTGTAAAATGAAGAAATGTCCTGAATGATCT AGTCTTTCAGCTGTTACATGCCATGGTTCCTACATATATTTTACTTCTTTCCAAAGAAAC AGAGTTCTAAAAAAGAAACCTCAAAGAACAAATGGGAAATAAAGGAAATAAAATGAACAA AACATTCTGAACCCATAAACATGGTACAACAATAATGAAAGTACAAAAGAAAAACAAACA AAAAACCCTCCATTCTCTTCTAAGCAAAGTATTTATACTTAAATTTGCATTTAAAAAAAC TTCAAGGAAATTTAATATAAATGTGCACGCATGTATATATACTTACAATAAAAAAGCCAA AAGACCAAAAGCCATTATTTTTTCTCCACTTGCGAAAGATGAATGAAAGCACATATGTGA GGAATATAAGAGAAACTGCACAACCAATTATGCATACCACCTGCAAATAATGAGGATCAA TGGCAAGATTAGAAATGGCAGGTCATAGAGGGAAAGAGGAGGGGAGATAATCAGGTCATA AAGCTGCCTAAGGCAATTTTCTTATTTTCTTGCATATTACATGCCTTTTGCTAATGACAA AACATTCATGAAAATGAATTTTCATTTTGATTCTACTATTATAATTGGCTTGTGGAAAAA ATGATCACTTACCAAAACAAACATGAGTTCCCATGAAAGCTGGAATCCCAGAAATATGAA GTAGTAAATTAAATGTATTGAAAAGAGAATCAAGAAGTATAATGGAATGTCCACCAGAGC CTGTCCACACCAGTATGCTGAAGGCCAGAGGCCTGAAATCCATAACTGGGATTGAACATT TTTCTGACAAAGAATAGAAGGGATAGAGGAAGGGATCTTAGTTTGAAAAGATTTTGTGGT TATGTAAAAAAAATTGTTTAATAAATTTTAGAAATAGTATGTTATAGTGTCTGTGTGACA AAAAGCATCCTCCTAAAAATCTAGCATCTCCAATGGAAATGTGTAGTTATTGGTTCAACA GAAAAGTCTCAGCTATTTTTAAAGTTAATTTACCCATTGATACAGATTAATGAAGATGAC TACACTATATATTTTTAAAGCCCAGTTTATTAAAGCGTAGTTAAATAATTGGAAACACTG TATGTCTGACATTTCATGCTATAGTTAAAAATCTAAATTCCCTTTGGAACTGTGAAATAA CTGCATGGATCAAACAGTACCACATCTTCATCCCTGAAGTTTATTTAGCATGATTTCCCT TACAGCTGTGGCAATTTTATTGTGCTAAATGGTAAACTTTCTGACCTCTTTGAAATCATG TGTTTACTATAATCTATACTGATATTAGATTGTAATGTATGTGTAAAAACATTAACCAAA GTACAACTGTGTGTGTATAAAACAATAAAATTGCAATTACTACAGTCAAATAAAATCAAT CTCAATCTAATTTCCTCTCTCTCCCTCTTACTTTATAATCGCTGATGCTGCTCATGCCGA TAAAAGGAGAAACGCAGTTTGTGATCAACAACAAAAATATGGACCCATCTATAAAACCAA GATCCAGCACTATGTCATCCTGAAAGATGAAAACACATCAGTAAGCTGTTGCAATTGTTA CAAATTATACAAACATTATAAGATACGTTTCCAGGAAATAAAGAAAAACTCTAGAAGCAT TCACCTGATTTAAGAAGCAAAGAGACAAGCAAACATGTTTTGTTAACCTTAGTGGCAGGT TCCATTCCCAGGAACAGCATGATATAAAAGAAATTCAAAATCTCAATTTTATATGTATAT ACGGTAGTCTCCCGTTTCCACAGGGGATATATTCCAAGACTCCAAGTGGATGCCTGAAAC CTGGATAGTACCAAACCCTATACATAATATGTTTTTTTAATCTGATAACTGAAATGGCTA CTAAGTGACTAATGGGTAACATATACAGTGTGGACACACCAAACAAAGGGATGATTCACT TCCTGGGTGGGAAGCAGGACAGGGCAAGATTTCATCATGCTACTCAGAACAGCATGCAAT TTAAAACATATGAATTATTTATTTCTGGAATTTTCCGTTTAATATTTTAGAACTACAGTT GACCAAAGGTAACTGAAACATCAGAAAGCAAAATCACTGTGAAGGGGGACTATTGTACTT AGAGGGCATGAGCAGTTTCTCTTTTACATTTACATCTGATATTTTAGGGAGCTACAGTTA TCATATCTGAAGCACTGAGTTAAGTTGTCATTTGTTCCAGTTCCCTATTTCCAAGTTGGC CTCTAATAGTGATTGTTGTGAAGCTGGACTTATGCTTAGGCATTATGCCTAACTACGTGC AAGATACAATTAGAAGAGAGCAAATCTTCCCTGCCTACATAATTTGACTTCTAAAATTGT TTAAATTAAACAATTGTCAAGGCATTGAGGGGTCTTTAAGTTTTTTTCAAGACACTGTAA TTTATTATTATTATGACAAAAAAAATCTAAAGAAAAGGAGTGCAGAAAAGGTAAGTTTTT GTCATAAATGCAGGTGCAGGTGGAAGGGCAAAAAAGAAGCAATGAAAAGGTTGTTCTAAG AGTATTAGTAAAGATGTGGGAAGAACCAGATTACCAGGGGCTAAATAAATGCACAATCAT CAGTGTAAGGGAAGGGTAACACTTATGACTCCATATCCCTGCTTCCCAGTATCACCCCTG GGAAAGGATATTACCCATGTTGTTGATCCTGTTGCTTAATATTAAATGGGCCAATGTCAT TGGTTGATGCACATATCTGTTTTCCTCTCTAAGAATCGGACAAGACTTCATCATGCTACT CAGAACAGTGTGCAATTTAAAACTGATAAATTATTTCTAGAATTTTCTATTTAATATTTT TCAACCATGGTTGACCAAGGGTAACTGAAACCGCAGAAAGCAAAATCATAGATAAAGGGG GACTACTGTACTTAGAGTGTACAAGCAGTTTGGGTCCAACTAAAGAGATACCTTTTTTCT CCTTTATATCCTGCACTCTCTACTTGGGTGTACTGCTTAATTTTGCTACCCTAAATCTCT GCTTTTCTTTGCTCCCCCATCTCTCTTCTGCATATCCTCAACTTCATCCTAATGATTCCC AAAGTATGCATTATCTCCATCTACTTCTCTGGGTTCCTTGCTTTTAAAATATTCTACAGA AAGTATCTACTTGGGTATACTCTGCTTTATCTAATATACTAAGTCAAAAACTAATACTAG CATCTCCTCCAAATAAACTTTCCTTTTCAACTTCCCCATTTCTATCAGTAGTTTTGTGAC TGTTTCAATTTCCTAAGCTACAAAATTGTCTTCTTACATGCATACCTCTTTTTTATACTT CTTTCAATCTGCCATTTAATGCTACTATTCTATGAAATTCACATGAGTTTTTCTTTTGTC ACTTATTCCTCTTCCTGTATGCTGGTCCAGACACTTTTGTTAGCTTCTGTTGGTCCTTGA CTGGCATTTGAATATTAATATATGGTAGGAGGATCAGGGGGTCCAGATACACAGAAGGTC AGAGCTAACCAGTGAAAGTCATTATTAGGCAGAGTTCTAATATAGGCATTTGAATCCTTC ACCATTGGGATTCCAATGCCATATTAGAACTTGACTTGTGAATGTCCAATTACGTTCCTT AGTATATTTCTATTTATAACTTAAGTATATCAACTTCAGAGGCATTAGTGAGAACTAAAT TAAATAATGTATAGTGAGGCCAGATGTGGTGGCTCACACCTGTAATCCCAGCACTTTGAG AGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGT GAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCCGGGTATGGTGGTGCATGCCTGT AATTCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGGTT GCAGTGAGCTGAGATCTTGCCACTGCATGCCAGCCTGGGTGACAGAATGAGACTCCATTT CAAAAAAAAAAAAAAAAAAATATATATATATATATATGTTATATATATATATAGTGAAAT AATAATATTTTTATTTGCTACATGTAGCATTTGCTATATGGGAGGTGCTCAATAACTAAG AATAGTTGTTTTTAAGATGAAAGCACTAGAATTTAAAACAGACCAGGAAGCAATATCAGG CAAGAACCAACAAGTAGCTAAGGAACAGATGACACGTAGCTTAGTGAAGTACACATTTCA AAGTCTAGAAGGATAATAAGAAACAAAAAGGGCATAATTTTAAAATAGTGGGAAAATGAG GTTATTAAGAGAAGTCATGACAGCTTTAGAAGACACCTTCAGCAATCAGAGGCAATGTAC AGCCAAATCTAGACGCAAGTGAGCCTCACAGAATTGTGGAGATAGTGACTCTTCTATGCT AGTGGTTCTCTAAGTGTGGTCCCAGACCAGCAGCATCAACGTCACCCGGTACTTACTGGA AATGCAAGTTCTCAGACCTCACATCTGATCTACTAAATCAGAATCTCTGGGGATGGTGTC CAGTAATCTGTTTTAACAAGCCCAGCAGGTGATACTAGTGTATGTTAAAGTGGAAGCACC TCTGGTCTATGACTTCTGCTGGCATATAAATCAGCCCCAAGATTTGAGGTGTCCCTGAGA AAGGATGTTATTAAATCTGAGTAAAAGGGAAATTGTGACTGAAAATAAAAATAAATTATC CTCCACAATGGGTGAGCAGTAAAATATACTATACTAATCCCTATTCTTACTATAATTGAT CATTTTGTTTGGTTATGCATGAGTAAAAGAATGAATAATTATTGTTTTCTTTAAAAAGAA AATACCTGTTTCTGGTGAAAATGCAACAACTAGAAAAAGACTGAAATTCTTAACTTTCCT AAAGAAACACAATTTCCATTTGAATATTTTAAAAGTTATTCATGAGGGACTAAGAGAGAA CTCACCTTCCCTGGATCCACAGGAGACAATTTAATATCCAAATTGCTTCCTTGACAAGCC TTCCGAACATTAATTTTGTCTAGATTTATATACATTGCAAGAGAAGAAGGTTATGTATCT ATGCATCATCTCCTCTGTTTTCTGATTCGGTTTAGCAAAAAAGTAGATTAAAGAGCTCTA TCTGTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCACACCATTGCACTCCAGC TTGGGTGACAAGAGCAAAACTCCATCTCAAAAAAAAACAAAAAAACAAAACAAACAAAAA AAAAACCTCTATCTGAACCTCGTCAAAAGGGAAAAATAGAACCCCATGTAAGAGACCTAC CTAACATGTTGGAGCAATCAACAACGAATGTATTTGATGTCTGGAGGTAATATGCTAAGA CAAATATTCTGTGAGTTCATGAGTAATAATCTTAGTAAGCAGATTCAGAAACTAAACTCA GGTAACTGATGGGTCCCTCTGGGGCCCACTGGCCACATGAGACCCATTCAGCTCTGTGCA GGGTGAAAGGCTACCTGGAAAAGATAAATGTGTGTCATACTGCATCTGAAGCAAAAGCCT CAAGAGTAACTTCTTTCCTCAGCTCCATTTCTATTTACTCCACCTAAGGATTAACATAAC ATTCCCCAAAACACTGGGGAAAAGAAAGGAGGAAGGAAGAAGCAGAACAGTCAAAAGGAA AGGTACCCTCTATCAGACTGCAGGTGATAAGGAGGTCAACCCATGCTACTTTCTGCATGA GCAGAATTTCTTTATCTTGATATTCTCTACGGAATTCTCTTTAGCAACACCCAGAGGCCC TGGCAAGCTTCCTGCTACCATTGAGGGGAAAACCCCAAATACCATCTTTCTTCCTCCAGA GCTGGCTCATGCTCAGCCAGACCTATTTTCCCTACAGAGAAAGCTTTTTTATTAAATGCA GGGTGAACTACAGTGGTTTGCACTCAGTAAACCCAGCATACATTCAATTCTGAAAAATCC GAAAGCCCTTTAAATCATATTACTTAAAAGTTGCAAGATAATTTTTATGTCTTTACAGTA ATGAAGAGTTTGTCCGACAAAGGCTAACTGTAACATGCTTCCACAGTAATGATAATAATG GCTCATGGTTGTGCGATACATTAAACACTTTTAAAAATAATATCTTAGTTGAATGTTACG TCTACTTTATGAGGTAGAAAAAGCAAGTATTAAAATAAAAAAATTTTAAAGACAGGACTA TTACAGATTATCTGCTTGCAGTTCCCATCTTGCAGAAGAGAAAGCTGTGCCATAATGGTA ACAAACGGTGCACAGCATAACCAGTTATCCAGTCTACCCACTCATTCATCCATTCAACAA ATATTTATAGAGCTTCTGCTCCGTGCAATGCATCATCCTTTGTGCTAGAAATAAGTCAAG TATAATTATTACTTTCAAGAAGTTCATATTTGAAAAACAATGACAAACTGAGTCTGAACT CAGTTCCACTGAAAAATAAATTAGGAGGGTCTTTAAGCATTAAAGCATCTGCTGAAAAGT CCTGGAGGATGTTAGGAGATTGATTAAAAAAAAAGGGAAGACAACATCGATTCTATATTA AAAGTAAACAATTAAGGGTAAATAAAGGCATGATTAACTCTGGAAGTACTGGGAAATAGA TGAAATTATATTAGATCTCACTCTTGAGAAATTACCAGAACTAAGTTTTGATTATATTTT TCTTATTTTTGCTCTGAACTGGTAGCACATTGCTATTACCATCCAGAGAGACACTGTATT GTTTTATATTAGATAGTTTCTCTACTTACAATTAAATCACCCTATCTCATTCGCAGAAAA CTAGAGTTTGCATTATATGGTATTAATTTCTTATTATGCAATTTTCCAATAAAATTTCAT TATCTAAAACCACTATGCATATTCTTGCTAACATCCACATGATTTCTATAATTTTTTCCC TTTTTTATCTATCATAATCAAACACACCAGTTAAGAATTTGACAATTTAGAAAGAATAAC TAAATTGCATCTGATCAAAAATTGCACTTCACACCCCAAGTTATAAAACATAAAGAAGCC AAACCAAAAAAAAGCACTGCAGAATTTTAAATGACAAAGAACAATAGAACTGTTAAAAAA TCATAATTTTAGAATTGGACCATATTTTATCATAAATCCCTTTGGTGGAGATATACATAT ACATATGTGGGTGTGTATACATACATACACACTCTTTTGCATTTGCATTAATCAGCGTAT ATGTCTTATATTCATCTAACTCTCCAGGGAAATCTGACACTCTGACATAAAATTAAGGAT TTAGGTTTAAGATATCTCTGATATTCTTCATTTCCAACCAAATCCATTCACTGATTTAAG TAAATACGCATTGAGTACCTAGTAAGTTGTATATGGTAAACCAAAGTCAAAATTATGAGT TTTCAACAGTCCTATGATTTTTTTCTCTTTTATTTTAAATTTTGCAGTGTCCTTTTGGAT CTTGGCTCTTCTAATGTTCTGTGTTGGACTGTGATTCTTAATCAGACAAGATTTTAAACT AGAGGGGTGAGGCCAGCCATAAAACATAACTCTACAGCATACCAAGTGGTAATAAATGTA ATGGAAAAAATAAATCAGGATAAGGGATAGGAAGTGATAGGTTACATCTAATTTACTAAG TAAATAATTATATATTTAAATTTTTCCATAAAACTTTTGAATTTTAAAAATTTAATTAGA CTAAACATAACAGTACTTGAAAGATTCTTGATCTTTCAGAATAAGTAATAGCAAACATGT ATTTGAATGTTTCCTCTTTCCTTTATAGGAACGTAAGCTCCATATGGGTGAGATTTTTGT CTATTCTGTTCATGCTGTATTCTCAACATCTAGAAGTACCAGAAAATAGTACACTCAGGA AGTAGTTATTGAATAAATTTAAATGTGTATATATATTTATATGTAAATATATATATATAT GTATGCCATGCTATGTTCTAGGTACTCAGTAAATTCATTTAATCTTCACAATAATTCTAT AAAGTAGGTACTATTACGCTCCCTACTTTGCAGATGAAGACACAAAGGCAAGGAGTAGCT AAGAAACTTGCTGTTAAGTGGCAGAAACAAGATTTGAACTCACATGGTAGGCTCTAGAGC CCTCATCCTTTATCCCTCTGCTGTGTTGCCTCTTATATAAGTCGAATACTCTACTTACAC GAGAAAATGAAGTGCTCTCCATTTGAATAAGCTCCGTGAAGTTAAAAATTCCCATAAGGG CATTGCTAACAATTCCCATAAGAACAGGAAAACAATTCAATTTCTTGGTATTACACGCAA CAGAAAATCTGTAATCCTTGAAAAAAAGTACACAAATATAAGTTATAAATTCTTATAGTA AATATATTTATTGTATACTTTGTATATTACCAGAGTGGAATTAGAATGAGAAGGAGACTA TTAATTTTTCTTTGACACTTCTGCCTTCTTTGAATTGGTACAAGAATGCATTATTTTTGT AATTCAAGTGACTTGTTTTGTAAATGAAATGGATTAACATTTACTAACATGAAAAGATGT CAAATATTTATATTTTATGTGACAAAGAAAGTTTCAAGCCTCCTCTAATATGATGCCAAT TTAGAAAACATACTTAAGTTTCCTATAGTTCTAAGTATTAGGACGTGGCAAAAAAAACAA AAAAAAACCAAAAAAAAACAGTGCATAGAAGCAAACATACCTTCTGGTCACCAGACACTA TGATGGCTCCATTGTAGGAGGGATCATCTGAGCCATTTCTGTTTCTAAAGTCATCTATTT CCAAAACTATATCCTGACACTTCAGTGAATGCACGAGGTCTTCAATATTTGATCCTAACA TAGTGGAAGGAAGGCAACAAGAAAAAAAAAAAAAAAGCAAGAAAATCAAAGTCAAAGCTT AAAATAATAATGATTGCCAATCGTGTTAAGAAAAACCCAGAATAGCTTAGTAAAGAGCCT TGCTCTTTAGGAGTACAATACTATTCATTCTGATGCTACCACATTAAGTTCCATTTACTA TCTTCAATGTGACGGACTCCTTTATTCTTTTCAGAAATATATTCATTTATCTTATAATTC TCACCAGGTGAAAAGAGTTTATGAAAATAAGATTGCATTTCTCACAGGAAGAAAATTTGC TAGGAGTGACTTTTATAAACTTTACCAGAACCCTGTAATATTTGTAATTATGAATAATAC ATACAAAATATACCTCATGACCCAGGCTTGTTCTAGTGATCCTGTCAACCTTAAATGGCA CTAACCTTGCCATGATATTTAAAGTACTAGTAACCCATTCAAAACATCTTTATGGAATTA AGTTAACTTGATATTTGCCATTGTGCCCATTATTTTTCTTGACTTGATTTCCATCATAGA TGGAAAGGAAGTCAAGTTGGTCACAGGGAGAAGTCAAGCTATGATGCAGCCTCCACATCT GAATCAACCACCCCCGCACCAAGGGAGCTCTGGATTTAAAAGGACCCATCAGGGAGAGAA TCCACAGATCCTTTGAAAGAGGCGGCTTGCAGCTGCAGGCTCCATGAGACAGCTGAAAAA CTGAGTGCCCTCGGTGTGAAAGGGCAATGTGTGTCCCCAAACACACATCCTCACTGGGGA ATCCGAAGGTTGAGATCACGGGAGGATTTTACCTTACCTGGAGCTAAGACGAATTTAGAA AGCCAAGCGAAATATAGGGGTAGAGGAAGCAGTGGGAGGAACCCTGTGGGCACTCTCAGC CCCCAGGGAAGCCATTTTTGACTTTGTCTCAGAGGGGTCCTTGGGGAGGGCTGCCAGTGG AATTGGGGAAAGACCACAGGAAGAAGGAAACTTCCAGCTGAACTTTGTAATAATTTTAAC CAAATGCATAGTTTCCTGGACAGAATCTTGGGGAAGGAATGATCAGGGAGTGCAGATTCA AGCACAGAAGCCATGGCAGGGGGAAGGCACATAACCGGAGAGCCCTGCTTGCTTTCTCAA AGGGAGTCTTGTAGCATGGGGTGAGTTCTCAGTCCTGCTCACCAGCTGCCTGGAAACAAA CTCAGTTCTGTTGTAGGGGCATTGAGACCACTTTGCGGGCTGTGTGGGAACTGAATGAGG CCTGTCACTGCCGGCTTTCCCCTACTTCCCTAGCGACCTGTACGATGCAGCAGAAGCAGC CATAATCTCCCTGGGAACATAACTCCATCGGCCATGCCCCACAGGAGCTGCTGCAAGCCC TGTCCAAGTACAGTCTAAGCTCAGACGTGCCTAACCCTGCCCTCACCTGCTGGTCTTTCT CCACCCGCCCTGGTAAACATAATCTCTTGGAAGTTCTATGGCCCTGACCCACCACCTGAG AAACCTGAATACTTATCCAGGCGACCCTAGGGCAAGCTTGCATCCTCCCTATACTACCAT AGCTGATGCTCTCTTGAAAGTGCCACCTCCAGGCTGGAGGCTGACCAACACTGTTCCAGC ACACTAAACAAAACTACAACCAAGGACCCTCACAGAGTCCACTTCACTCCCCTGCTACCT CCACCAGAACAGGTGCTGGTACCCACGGCTGCGAGACCTGAAGATGGATCAAAAAATAAT AGATGTTGGCATGGATGTGATGAAAAGGGAACACTTTTACACTGTTGGTGGGAATATAAA CTAGTAAAACCACTATGGAAAACAGTGTGGAGATTCCTTAAAGAACTAAAAGTAAGTCTA CCGATTGATCCAGCAATTCCACTCCTGGGCATCTACTCAGAGGAAAAGAAGTCATATGAA AAAGATACTTGCACACACATTTATAGCAGCACAGTTCACAATTGTGAAAATATGGAACCA GCCCAAGTGCCCATCCATCAACAAGTGGATTAAAAAAGTTATATATATATGTATATGTGT GTGTGTGTGTGTGTGTGTATATATATACACACACACACATACATATATATAACTTTTTAA ATACACACACACACACACACACACACACACACACCTTGGAATACTACTAATCCATAAAAC GAAATGAAGTAATGACATTTGTAGCAACCTGGATGGAGTTGGAGACCATCATTCTAAGTG AAGGTAACTCAGGAATGGAAAACCAAACATCATATGTTATCACTTATAAGTGGGAGCTAA GCTATGAAGGTGCAAAGGCATAAGAATGATACAATGGATTTTGAGGACTTGGGAAAGGGT GGGACGGGGTTGAGGGATAAAAGACTACACATTGAGTGTAGTGTACACTGCTCAGGTGAT GAGTCCACCAAAATCTCAGAAATCACCATTAAAGAACTTATACATGTAACCAAACACCAC CTGTTTTCCACAAACCTATTGAAATAAAGATAATACAAAATAAAAAATATTAAAAAAGAA AATTAACCCATCAGTTTCCTTCATTTGAAAATGGAGCAAGCTGGATAGACACCATTTTTG TTTTCAATTGTCTCTCAGGTATGTGCTTTCTAAAGATCTTTGATAATAAAAACTCACACT AAATTTCAGCCCCATTTCTCACCTGTATTATTAACGATTAACAGGCTGGTAAGAGGCGTC TTCGGGATTTGTTCCAGAGAAAGGAAATACATACTGGGTGAAAACTCCCAACAATGAGTT TCACGAGTTACTTTATACATTATCTTCTCTAGAATGATGGGGATAAAAGCAATTCCAAGT ACTAGTAACCTAAGTAAAACAAAATTATAACATGAGTCTGAAGCAATTTTCCTCTGGTTA TTTAAGTCACAAAGATGCTATATAAGTGCTAACTATGGAAAGTCCACATGCATATGTGGT GTTTAGTTAGATAAAATGAAACATACAGTGACAGTAATCTGAAAATCAGCACAAAAAAAT TACATACTTTGTATCACATTGGAAGATATTCAAGGGTAACAGAGCATCAAGAGAAAAGGT GGAATCCAGGGGCAATCCTCTGCAGGTATGCTGGTTTACCAGGAAAACACAGGAAATGAT TTTATGAGATAACAGGGGCCACAAATTGCCTGCTTGGGTACTTTTGATGAGAAAGAAGCC CTATTTTACACTGCAGCCTCAAGCTTGCTATGTGCACAATTGCAAGTAAAATTTTAACTT TCTTCAATTGTTAGTTTACAAATATTTTAATTTTCAGGAAACTAAATGCAATATTTAAAA CACTATTTTTATATCCTAGAAGTCATCCCACCAACTCAAATTGCAAGTGAAATGCTTCCA AGCAATCTTTGTTTCTCTAATAAGCCATGAGTCCACTCTGCAATGACTACTTTCCCATCA GACTTCATACTCTACCTCCTTCTCCCTATCAGCCATATATTTCATAGAAAAAAAAAATGG AGTCTATAGGACAGAAACTCCTTCATCTTATCGCCGCCAAAAGAAAAGAAAACACATACA CAGATTCAGTCATCCTCTCATTCTTTTATTCTGTTGAAGTAGATAATAGATCTTTGCTCC TAACAAAAAGATCAGTCCTTGTCAACATTGCGATGAATCCAAACTCTCCACCCTCCGTCT ATCTCTCATTCATTATAAAATCAACTTTCTTCCCGACTTCACATTGCCTTTTAGCTTCTG CTCTTTCTACTCCGCTCCACAGTCAAGCACCGCAAAAGAGTTGTCTACTTTCAGACCTTC TCTTGCTAAAACCTTTAATAACTTCCCTTTTGCCAAATCCAATGGATGCTTTGTTTCTCA ACTGTTATTAACCCTCCATATTTTCTAATCTTGGCTTAAACGTAACAATTTCAGTAAGAC CAACACCAGCAAACCTATTTAGAATTGTAATGTACCTCCAACTCCTGTCATCCCTCCCTA TCCCCTTTTCTACTCTAGTTTGTATAACCTGGCATATAAGTTATTTAGTTTTATATTCAG TATTTTTCATCTTTTCCACCCAACCAGATGTAAACACCATTAGAGTAGGGATCTGTGCCT TTTGTGTTCACTAATATAACCAAAGCTCCTAGAACAATGCCTAGTATACTATAACAGGCT TCAATAAAGATTTGTGATATAATGGAACAAGTTTAAAGGCCTTATCAATTTTGTTCACTA CAGTAGTAAAACTGTGCCCCAAAGAGTTAAAGAAATCAATGACTAGCAGAAATTATTGAG TTTGTAGGGTGTCAGATTGAAAGAAGAAAAAAAAAAGAAACAATTTGCTGAAACACTGAA ACTCCCTCAGCTTGTAAGATAATAAAACTGGCTGAAATCAGCTGAAACCAATATGGCCAA TTACAGTCGGTCCAGAATCATCCTGCCGACTTCACAGCCTGAATTTCCACCATATATTTC ATACCAACTGCGCTTGAATTTGCACAAGGGATACATGAGGAGGCATGAAGAGATATCTGT ACATGCCTGAGGACTTTCCAGACCTCTCCTTTTCTTCTACCATGCTAATCCCAGGACCCA CCCCCTAAACCTTTGCTAATAAAATTACTGCCTTAAAGTCAGCACAGGGAGACAGATTTG AGCTGGTCTCCTGTCTCCTTGTGAGTCAACTAGCAATAAAAACCTTTTCTTTCCTCAAAA ATCCAGTGTCACAGTATTGGCTTCTAGCACATGAGGCAGTCAGGCCCTTTTCCTCAGTAA CAGCAGGATAGGTAAACATACAAAAAAACTGTTAAATGAATGAATAAATTAATATATTTA CTTTCTTAATATTTGAATGTTTTTTCATATACTGACCAAATAGATATAAAGTAATCTGAT ACTCACAAACACAAAAGAGCTCTCCTTTCACGCCTTAACTTTAAGAAGCGAAGTGTTGCC ACTGCATAGATTTGTCGTCTCCAGAGAGCTGCACTACTGACAGCCTTTCTTGTTTCAGGA AGAGAACAAAGAACCTGTTCCATTTCAGACTCATCTCCAGTATTTCTTGTCACATGTATT TTCTCTTGTTTCCCAATGTCAAAATCTACAATCATGTAATAAAACATTTTAATAGGCTAT GTTATCTGAACTTTCTCTTTAAAAACTTTGAAAATGATGTTAGACTATTTGAAACAGCAC TTCCAACAAGTTAAGCTACTGATATCCATAATCAAAATTTACGTTAAAAATCTTTCCTTC AAACATATGTAATGGATTCAGTTCCAATGAGACAGTAAATTAATTTTTGAGGATGATTAA GGCTTCCTAACAAGCATTTATTCTTTCATACCAATAACAGTAGCTCTTCACTAATGGATA CTTTTGCAGAGCAAGTTTTATGCAGAAGCACAAAGACAAATTTATGTAGCTGAGTTTCCA ACAGGCCTCCTCTGTCATCTGGAATTTCCCCTACAGGATTAGTTCAACACTGATGATTGA CATCTCAGTAACGAGTTCAAGACATTGTGCTTTCAAATGATGGAAAGTTCATGGAAAGGC CTCCTGTTTGAGTCCCACATATACCACACATTTACTGTATAATTTTGGCTAATCACACAA CTTCAAATATCAGTTTTCTCATGGGCAGCTTGATGTTATTATGGGAATTTAAAACAATAT AATTCAAGGACTGAGTACAATGGCTGGTATCTAGTAGCCTCCTAAATTCTTTTTTTTCTT TCCAATTTTTATTTTTGGTGCAGGCTTGCTACATGGGTAAACTGTGTGTCATTTAGGTGC AGGCTTGTTACATGAGTAAATTGCGTGTCATGGGGATTTGGGGGTTTGGTGTACAGACAA TTTTGTCATCCAGGTAATCAGCATAATACCCACTAGGTCATTTTTCAATTCTCATCCTCC ACACTTAAGTAGGCCCTGGTGTCTGTTGTTCTCTTCTTTGTATTCGTGTGTATTCAATGT TTACTTCTCACTTGTAAGTGAGAACATATGGTATTTGGTTTTCTGTTCCTGTGTTAATTT CTTTAGGATAATGGCTTCCAGCTTACTCCATGTTGCTGCAAAGGACATGATCTCATTCTT TATGGTTGCGTGGTATTACATAGTGTACATGTAACACCTTTTCTTTATCCAGTCCACCAC TGATGGGCATCTAGGTTGATTCCATGTCTCTGCTATTGTGCATAGTGCTGCAATGAACGT ATCTGTATATGTCTTTATGACAGAATGATTTATATACCTTTGGCTATATACTCAGTAATG GGATTGCTGGGTCAAATGATAGTTCTATTTAAAGTTCTTTGAGAAATCTCTAGACTGCTT TCTGCAGTGGCTGAACTAATTTACATTCCCACCAACAGGGCATAATCATTCCCTTTTCTC CACAACCTCATCAGCATCTGTTATTTTTTTACTTTTTAATAATAGCTATTTTGACTGGTG TGAGATGGTATCTCGTGGTTTTGATCTGCATTTCCCTATTCATTCATGATACAGAGCATT TTTGATATGCTTGTTGATTGCATGTATGTATTCTTTTGAGAAGTATCTGTTCATGTCCTT TGTCCATTTTTTAATGGGGTTGTTTTTGGCTTACTGATTTAAGCTCCTTATAGATTCTGG ATATTATACCTTTGTTGGGTGCATAGTTTGCAAATATTTTCTCCCATTCTGTATGTTGTC TGTTTACTCTGTTGATAGTTTCTTTTGCTGTGCAGATGCTCTTTAGTTTAATTAGGTCTC ACTTGTCAATTTTTCTTTTTGTTACAATTGCTTTTGGAGTCTTCATCATGAAGTCTTTGC CAGGACCAATGTCCAGAATGGTATTTTGTAGGTTTTCTTCTCAGGTTTTTATAGTCTTAG GTTTTACATTTAAGTATTTAATCCATCTTGAGTTTATTTTTGTATAGGGTGAAAGGTAGG GCTCTAGTTTCAATCTTCTGCCTGTGGCTAGCCAGTTATCCCAGCACCATTTATTGAATA GGGAGTCATTTCCCCATTGTTTGTTTTCACTGGCTTTGTTGAAGATCAGATGACTGTAGG TTTGTGGCTTTATTGCTGGGTTCTCTAACTTGTTCCGTTGGTCTATGTATAGTAGCCTCC TAAATTCTTCTAATTTTTATTACAAAGTAAACTAAGGAAATAACATCTTATTTTATTACT TCTTATTAATACATTAATTAGAATTAGTTTATTAGCTAATTAAGAGCACATTTTTATAAG GAATGGCAAGTAAGAGGCAATAGCAGAATTCATCGCTATAGCAGAGAGCTTTTGATAATA AGGAAGAAGTGGTCATTGCAAAGAGATGTGCCTGTCACTGACATGGGAAGCAGACAGATG TTGGAAAGCAATTTGCCTAGCACCAAGGCTGATTATACTCGATATAAAATGATTATAATA CTGGACAATGCTAGTATTTTCTATCTAGTGGACAATGCTATTTTCTATCTAATGCATATT ATAGGTAGAAATCCACATAAAAATCTACAAATATGAATTAGAACATCATCTTTTTCTCTT CTCTTTTTTTTCTTAATTTTCTGCTAGACACACATTTTTATACCTGGTTCATCAATTGCT GATTTTCCTTCTAGGTTCAAGAATACTTCATTCAGAGATGTCACTGAAACAGCATAATTC CTTATGCCCTGGTCAGAACACTTATCAAGGTCACTGTAAAGATCTAAAAAGCCAATAGTA ATAAGTCAACGCAATTAAAATTATCAATGAGTATATTAAAATACTAATTTCTAAATATTA CTCAAAATAGATGTCTACAAATGTTTTCATATTAAAGCAATCACAATAATCCAAGGAAAC CTTTTCTGTAAGATATTCTCTTGTCATTCAAATCAGTTTTAATATTTTACATTTCCATTT TGTTTCATAAACTTTAAAATTCTTGTATCATTATTGCTGTGTGTGTTTGTATAAGCATGT ATCTGTATGTCTATCTAAAAATTTATTAAGTTATACCTTATCCTTTGTATTTTCTAACTT TTCTATACTAACCATTTTATATATATAATAAAATTATTATAATTTTCAAAGACTCTATTG AACTGCTTACATATATTTTAAAAGATAAAGTCTCATTTCATCTGTATTTCTAACAGAAAC TGCTATTTCAGAAAAGAGATATTTCAAAGTTTAATTTTGACAAAGAGTGCAAATCGGGGT TTCTATATTCATGGAAATTTTAGTTGCTATAATACGTCCCTGGTAACATAGATCATCATA TTGGAAATAGGAACAGATTACTTATGAATAAATATTTTCATTTGTATAAGCTTTAGAACT CGATTCATAGAACAACAGAAAATGCAGTCAGCACAATCGTGAACACTTACATATATTCTA TGTGATTACACAGTAAGTTACCTGGAAATTTGTTCGTTTTTTCCAAAGGCAAACTATATA CAAGTTTTTCTTCACTTTCTGTTGTTAACTTGGCATCAGGAATGTGCTGCTTAATAAGGG ATGTGATTTTTTCTGTGTCACACATTTCATTCCTGTGTAAACTATTATTTCAAAAGAGCC ATAAGTCTCTTGAATTCTTTTCCAACACCACCACTCATGAAAAGATAGTTTTCTATTAAA CAGCTTATATGTATTACAGGCATATTCTACTTAACTCTAGTAATTGGTTCCTGCAAATCA GATACTCCACTTCAAATTGCTAATTCAACTTCAAAGTGCTAATTGGTAGCCTATTTTGCA TTATTTCAAATGGAAAAATTATAGTACATATCAACACCAATTCCTTTAAATGTAACTAAA GCACAGTGACATTTTAGCATACATACACACATACACAAACACACATACACACATGCAAAT ACATGTGTATAAAAGTTATTTTATGTGTGTGTATATATACATATATAAAACTATCATTAT TGTGCTACATGTGTGATATACATAAAAAACAATCATGATAGGATATAAGATACATGAAAC ATTGCTTCTGAATAACTGGAAAATTCATAAGGTTTTTAATAAACAGTTGCTTTCTATGCA TTAAGTGGTTTCTCTTAATGTCAACAACTTCTATTTGCAGAGCTTGTTTGTGAGTATTTG ATGCTTTCTAAAATGTTCCCATGTGATATTCTGCCATTCTATCAATTAGATTTGGAATAT AACTACAGAAATTTAGGCCAAATTGTTTTGCTAAAAGTAAACAATGGCTTATTGAGGACA TAAAGATAATTTTTTTCTATACAAATATTGGCTTAAAAATGTCGTATAGGCCGGGCGCGG TGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCAGATCACGAGGTCAG GAGATCGAGGCCATCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAA TTAGCTGGGCATGGTGGCGCATGCCTGTAATCCCAGCTATTCGGGAGGCTGAGGCAGGAG AATCGCTTTAACCAGGGAGTTGGAGGTTGCAGCCACTGCACTCCAGCCTGGCAACAGAGC GAGACTGTGTCTTCAAAAAAACAAACAAACAAACAAACAAACAAAAAAGTTGTATTAAGA AGTATACTTTGTTTTTTAATTAGCATGCTTAAAACCAAGAGATAACCAAGAAAGGAAATG TTAATGAGGAAGACATTTTGAGCTGTTTATTGCAAAACAGTTTCTACCAGAAGTTAAGTT GCCTTTCTTATATTTCTAAAGGCTTCTACAAAATGTCACCCTCATATTAATATGCTCATT TAAAAATAACTACACCTAGAATACATACCTTAAATGATATCCAATACCCCACTTTCGCTT CAGAAACAAAGATGATCCTGCACATTTCAACTTCCCATTAGACAGAAATACTTTCCTATC TGAGTAGAAAGGAAGATTCAAAAAATTATGTGAAGAGTAATTCCTTATATGGTATATTCT CTACTTTGGATACTAAAACACTGAATGAAATTTGTAATATCAATACAACTGTAATATCAT TAAGCCCCTGGGTGCAGTATCATTTCTAATCCCCATGCCTATTGTGAAACAGGCCTCAGA AATTCACTGCATTCCCCATAGCTAATCCAGTGCCTCAAAACTTTCCAAGGATGGCCTGAT TCTTCACCTCTTCCTTTGTCCACATACTTTGCCATGTAACTTTGCAGGGTTACACCCCAT GTGACCTGTTGTAGCCAATGGCATGTGGAGGCTTGAAATGGGCTTCTGCAAATAAACTGC AAACAAGATTTTCTTCTTTTGAAAACAGGCTATGAAAAATAACTCTCATGTTAAATCCTT AAATAACTAGTTGGAATAAAGAAGCCAAGAATCACCAGCCAAGATGTCAGCCTCATCCAT GAATTGGGTACTGAAGAGGATAAGTCGGTCTACTTTATGCTCCTTCAGGAGGCTCCACAC TCGGTGTCTTGAAAAGGGATCCAATCCAGCAGTTGGTTCATCTAGCAGCAAAACCTACAG AGGAGGAAACGTATGAAAGCATCTTCCTCTTCACAGTGAGGATCTTCAGAAAGCACCATG AAAACAAGTATGATTTCTAGACTCAAATACAGTCCTCCACCAGATCCCTAACAAGCTTGC ATGGTACTTTATTATAAATTTTCCCTCACATTTGGTAATTACAGTAGAAGTTGGACTTTA ATAATAGTTGTATATCCTTCAATCTAAATTAATTGTAAAAATATATTTTTTCTCTCACCT GAGGATCTCCTAAGATGGCAATCCCTAGTGTTAGTTTTCTCTTCTGCCCACCACTTAATT TTTTAGCAATAATGTCTTGAATGCTTTGCATGTCTAATTCCATTATAATTCTTTTTACCT ATCAAAGAAAACTCTGTGTTAACAATATCAAATATTTTACTTTAAGGAGTTTTTACTCTC TAAAAATGAAAAGGATTTAGTCTAGAACTTCGTTGATTAAGCTTTACCTATCAAAGAGTA GAGTAATAGCTGAACAAAAAAAATATATAGTCAAAAGTAAATTATTTCCAAAGCCATCAA TCTTAATGTGTTCCTGTACCTCTTGTTCCACTTCCTTTGGCTGAATCCCTTTTATTTTAG CAAATACCCTGAGGTTTTCTCTCACAGTGAGGAAGTCAAATTGAAAATTGAACTGTGGAC AAAATCCAATATTCTTTCTAATTTCTTCCATGTCAGTTATTTCAGAGAGTTGAGTATTAT AAATAGTGGCTGATCCTATAAATAGAAATTTAAAAGGCTTTACTGCCAGAATGTTAATTC TATGCAGAGTGATAATATATGTTAGTATTTAGATTTTGTTCAAAAAACTTGTTTTTATTA AAGAAACTTCACATTTTCCAATTGCATAATTAATACATTGAATAATTCAGATTACTGTTA ACGTAAATATCTGTGTCCACAGCAATGCAAAATATACATGGAATGTCAAATAATAGTGGA ATAGAGATACAAATGTTTTCATGAATTTATGTGCATATGAAATCAATATTTCCTGCTCTA AATTATTCAACTGTGTAACAAGTCCAATTTAGAGAAACATTTTTTACATAATCAAACCAA TTTACAACTTGCTTTTTCAGCCAACTTACTTTATAAAACTGTTTTCTCACCTTCTGTAGA AACAGACAATCCACTAAGAATGTTTAGCAGTGTTGATTTACCAGCTCCATTATGCCCAAG TATTGCAGTGATCTGTCCTTCATATATGTCAAAAAATATGCCTGTTTTAGAATAAAAAGT GGAAATTAGATTTTGGATTATATGCAGATGGAATGGACCTTAAAATTGGAAAAGTAAAAT ATATCTCAGCATTTCATTTCATTGGTATTTTAATACATCCCCTATAAAATTATACATTTA ATTGTATAAGTTATGTATTCCTGAAGACAAAGCTTCAATTTGGAGAAATTGGATCAAGAC TGGGAATATAAATTTCTACCCTCTTGCTTCCTTCAAATCCTTTGAATGTCAAAGAATCTA TACACTTAATATTAAATAATAAAACAAAGACTACTAGAAATAAAAACAAAACGTAGTTTA TTTGCTTCCTAGGCAAAGGAAAGAAGTGTGGCTTAAGAAATTGTCTCCCTGAGGCTTGCA GAGCTGGAAACAGAAGGGCTGGGTATAGAGAAAAGGGGAAGAGTTTATTTCATATTCGGA GGGAGGTAGAACTGATAAAGAAAACATTGGTAAAGTATCTCCTGGTACTGGTCATCATTT TGCTTTATATCACAAAAGTGTGGGCATGATATTTAGAAATATCTGCTGGGATCTAAGACA TGTCACAGGCATTTTCACATATATGTGCCTAAGGCTTGACAACTTTTTCTTTAATGTTTG AAAACTTAACTCCACCGGAAAATAAGAATTCAGTTAGCATGCTGGAAATTTTAAAAGATT CTCTGAAGACAGAAAACAGAGGGAATTAGATTGTCAGAGCGTCAAAAATCAGGCAAACCA CAGGCCAAAATAGACGATGAAGAGTTCTATGAAAGTAAAACCAGTTTCACTAATACTTCG AGCTTAGTTTGATAAAGTCAGGTCAAAGATTATAAACCGGTATAAACAGTGTATTCCTAT TGTTGAAAAAATATTTTATATATAAATGTATATATACAAAAAAGATAATATATTATTGGT AATTATCCCTCATGGCAGAAACATATTTTAATTTTTTTGTTTTCTCTTTATTCTCTAATT TTCCACAATAATGATATTTTCACATCACAGAAATGTTTTTGTGTTTTAATTTGAAGCATT ATCAAACAATGAAGTTTTTCTTTTTTTTTTTTTTTTTTAGTATTTATTGATCATTCTTGG GTGTTTCTCAGAGAGGGGGATTTGGCAGGGTCATAGGACAATAGTGGAGGGAAGGTCAGC AGATAAACATGTGAACAAGGGTCTCCGGCTTTCCTAGGCAGAGGACCCTGCGGTCTTCCG CAGTGTTTGTGTCCCTGGGTACTTGAGATTAGGGAGTGGTGATGACTCTTAAGGAGCATG CTGCCTTCAAGCATCTGTTTAACAAAGCACATCTTGCACCGCCCTTAATCCATTTAACCC TGAGTGGACACAGCACATGTTTCAGAGAGCAAGGGGTTGGGGGTAAGGCCATAGATTAAC CGCATCCCAAGGCAGAAGAATTTTTCTTAGTACAGAACAAAATGGAGTCTCCCATGTCTA CTTCTTTCTACACAGACACAGCAACAATCTGATTTCTCTTTCCTTTCCCCACACTTCCCC CTCTTCCACTGGACAAAACCGCCATCATCATCATGGCCCGTTCTCAATGAGCTGCTGGGT ACACCTCCCAGAGCGGGTGGCGGCTGGGCAGAGGGGCCCCCCACCTCCCAGACGGGGCGG CTGCCGGGCGGGGGCTGCCCCCCACCTCCCTCCCGGACTGGGCGGCTGGCCGGGCAGGGG CTGCCCCCCACCTCCTGGAGGGGGCGGCTGCCGGGCGGAGATGCTCCTCACTTCCCAGAC GGGGTGGCTGCCGGGCAGAGGGGCTCCTCACTTCTCAGACGGGGCGGCCGGGCAGAGACG CTCCTCATCTCCCAGACAGGGTGGCGGTCGGGCAGAGACACTCCTCAGTTCCCAGACGGG GTCGCGGCCGGGCAGGGGCGCTCCTCACATCCCAGATGATGGGCGGCGGGGCAGAGGCGC TCCCCACATCTCAGACGATGGGCGGCGGGGCAGAGACGCTCCTCACTTCCTAGACGGGAT GGTAGCCGGGAAGAGGCGCTCCTCACTTCCCAGACTGGGAGGCCGGGCAGAGGGGCTCCT CACATCCCAGACGATGGGCAGCCAGGCAGAGACGCTCCTCGCTTCCCAGATGGGGTGGCG GCCGGGCAGAGGCTGCAATCTCGGCACTTTGGGAGGCCAAGGCAGGCGGCTGGGAGGTGG AGGTTGTAGCGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGCAACACTGAGCACTGA GTGAGCGAGACTCCGTCTGCAATCCCAGCACCTCGCGAGGCTGAGGCTAGCAGATCACTC GCGGTTAGGAGCTGGAGACCAGCCCGGCCAACACGGCAAAACCCCGTCTCCACCAAAAAA ATACGAAAACCAGTCAGGCGTGGCAGCACGCGCCTGCAATCCCAGGCACTCGGCAGGCAC TCGGCAGGAGAATCAGGCAGGGAGGTTGCAGTGAGCCGAGATGGCGGCACTACAGTCCAG CCTCCGCTTGGCATCAGAGGGAGACCGTGGACAGAGGGAGGGGGAGGGGGAGAGGGAGAG GGAGAGGGAGAGGGAGTTTTTCTTTTTACCTTGCAATGCTTCTACTTTTCCAGTCTTTCC ATTATATTCTTTTATAACATTTCTGATTCTGAAAGAAGATGAAGTAATTTTCATGTAAAT GCATTTTCTAGTATTAATAACACAGATTACAGTTCATAACTAAGCCTGAACTTCACAGTA AAGGGTATCACTCTCAGTGGGATGTAAGGAGGGCAGTAATAAAAGCCCTCCCCTGACCAC TCCCAAAAGAGATTTACACAGACCTGCTAATACTCTTATCAAACTTGGCATTTCATATAT TCCAGCTATTTCTCTAAGTTATCAAATAAATAAGGGAAAGCTAAAATTGAAAAAAAAAAG AAGGAAAGAAGGAAGGGAGCGAAAGAAAAAAGGGAGAGAGGCTTTCCCTCAATCCTGAAT CCCTCTCAATCATTATCTTTCACAGGCAAATTTGTCAAAATAATAATCTTTACTCCCTAT TTCCATTGCTTTATCCCACATTTATTTCCCAACCTAAGACAACATAGCTTCTCACTATAC TACTCCACAAAAAACTATTCCCAATGAAATTCACCAATGACCATTCTAGTTACCAAATCT AATGAACACTTTTTAGTCCTTATTTGATATACTTCATCACTGTTTTAAACTATTACTCAC TCTTTTGTTTTCTTAAGTCTCTAACTCCCTGGCTTCTACACTTTGGTTCCACATCTTCCT CTTACTATTCCGTTTTGGCGTACTTTATGGACTCCTTAAATTGGATTTTATACTTGGCCA ACTATTTTTCTTATTCTCAAACCTTTGCCATACAATCTTACCCACTCTCATGGCTTCAAC TCCTACCTAAATTCTAATGATTCCCAAATTTGTGTTTTAGAGATTTCTTCAAAGTTTCAG ATATTCTGCTTTTTACTATATATCTACACTTGGATATCAAACTGAACGCATTATATTTTC CTCTAAACTGGCCCACTTCCATTCTCTATCTCAGTTAGAATTTCTACTATCTACCCAGGA ACTCAAGCTAAGAGCCTGAGAGGCATCCTTAACTCTCTCTCTCTCCCTTTTTCACCCCAT CCTGTGACCTACAAAATTATTACAATTTAACTTCAAGAATTTATGAATTTAACTTTATAA ATCTATTTGAATTTATCTCTTTACTACTTTTCTTGTGCCTTCTTGCCCAGGCTCTTGTCA TCTTTCACCTCAACCAGGGCTATGACCTCTGTGCTTTATTTTTAATTGTCCCTTGTCTAT CAGCAACAGTCTCTTTCCTTCTGCAATGCGGAGGACATATCAGAGACTACATTTCACGGA ACCCTCTTTTCAGTATCAGATTTTGCTAATGAGAAGAACTTGGGCAAGATTTGGAGAGCA GAAATGAAGCAAGGTCATTATTCTCGGGTCACGTGAGCCAAGCATATACGCAGGCTCGAG GTTTGCAGCAGCTTCTCAGACTTCTTGACAAGGACTGCTTTGCTACTGCAGATTGAGATA ACTGGTGAGAGATTTCCCAGAAAATCCCTGACATTTGCAGCAGTATACTGACAAACTTCT TGAAAAACACCCATTTCTGTGCATCAGGCTAAGGTCCTCAGTGGCTATTTCCTGACTTTC TGGTTGTAACTTAACCTTCTCTCCTCTAACTCTTGTACATTTGTGAATCCCTAATCCCTG TATTAAACTCCTTTACTCCCACAATATTTCCAGCAACTCACTTTTCCTGACCAGACCTAG ACTGGTAAAATATCGTAAATATTTCCATTTCTCCAGTTGTGTCACCCTCAAATCCATTCT TCATAAAGCTGCCAAAGTGATCTATCAAAGTTCTGGTTACCTAATTTGCCTCCTTAAAAT CATTCAGTGATTCCCCACACTATACAGGATAGCCTAATCTCCTTACCTTGGCAAGCAAAA TCTTCCATGATCAGATTTGGTGCCTACCTCTTAAAGTTAACCTCTCTCTTTTCTTGTACT TTAAGGTCAGAAATGTTAGTTCCTTGTGTTCCCTATACATACACACTGTGTCTTGCTCTA CTAGGTGGCTTATGCCATATCCCCTGTGTGGAAGGACCTTCACATACCCCACCATACTTT ATATGACCAAGACCTTTCTCTTTCATAAGACTCACCTTAAGAGTCACCTCCTTTTGACTT TCCCCACTACACTACACTAGGTTGGATGATCCTTCTTTATTTCTTTTAATTCTCTGTGTT CAGCTCTACTACTTATCAGTTATCTATTTTAGTATCTATTTCCTTAGACTCTGTACTTCC TGAGGTTAAAGACTATCATTAATCTCTGTATCCTAATTCTAGCAGAGGGACTGATTAATG ATGAATAAGTTAAAAAAGTAATTAATTTGTCAATAGGAACAGTCTGGTCCAGAATGATCA AAGAGTTCCTGGTTTCAGGCATGTTAGGCCACTTCCTATAGGATGTTCCCTCTATCTCTA GGTACATATAGAGGGAATATCAAGGTGGATGACACTGTATGCAGGTTTAGACAGGCTAGA ACTGTCACAATTATCTGAGAGTACACTCAATTCATATTAATGTCATAAGGGCAAATTAGA CCCAAGACCACTGAATAGGATGACTAGCATCAACCACTTAGGAGACCTAAATAACCGCTC TTCATACCATACAACAACACCCATCTCCATTGTTCACTGGATTAATATGGATCAAACTCA TGATCCTGGGCATTTATTGAACCATGTCCTAAAAGACGAGCTTTCGGCCTGACAAAAGAG GAAATAATATAATTTAGTCCTAATTTAATTTGTTATGTGCAACAATACTAAATTTTCTGT TGTCAACGTAATTTCTATAAGAATTAATACCAAAGAAAGTGATAAACTATAGCTACAGAA TAGCTATAAAAGTTTTCATGCAGGAGATAGGACTTGAAAGACTACTAAAAATTATAGAAT TTGAGAAATTTCCTCAACTCCAGGGAATAGAGAACTTTCACCTTGATCTTTTCATATTAG GTTATAGTATTCTCCTTTTCCTGTTGTCTCCTTCCTCATTTCCCACTGCTCCCAGATAAT TTCACCAATCACCTTTTACGTATCTGTTTCAAAATAACGTGAACTGAGATAGGTCTAACT GATTTAGTATATTTGGGATATTCCTAACAGCTAATATTTATTGAACACCTAGCAATAGGC CATGTAAAAGCTTTACATGTGATAGCTCATTGACTCTTTATGACAAATTGTGTATTATTG TTATGCTCATTTTTAAGATGAAGAAACTGAGGCATAGGAGGTTAATACTTTAGCTGAAAT TAATAAGGGGCAAAGCCAGGATTCAAACCAGTTGGTTTAAACCTACAGACTACATCATAA TCACTATGATCTACTGTCTCCTGAAAATATACTTTTAAAAAGATAACTTCACACAAATAG AATGTCACTTAAGAATACTGCCCAAAAATCTTGAATAAAATAAGTAAATACCTAGGGAAG TATGCACTAAATTATAGAGGAATGTTTTACTGATGGCTCTCCCTGCTTTATTTCTTATTT GTTTACTTTCAGTCAATCAAACCAGTTTGAATATACAACTAACATTTATGCAGTTTCTAT TATGTAACAGGCATATATGCTTAATTATCTTATGGATTATTTATATTATTAAAGATGAAA GAGAGGCATTCTATTCTATTTATTTATTTACTTCTGAGACAGGGTCTGGGTCTGTCGCCC AGGCTGGAGTGCAAGTGGCGCCATACTGGCTCACTGCAAACTCCACCTCTTGGGCTCAAG CCATCCTCCCACGTCAGCCTCCCCAGTAGCTGGGACTACAGGCATGCACCACCATGCCTG GCTAATTTTTGTATTTTTTGTAAAGACAGGGTTTCACCATGTTGCTCAGGCTGGTCTCAA ACTCCTGAGCTCAAGTGATCTGCCCATCTGAGCCTACAAAAGTACTGGGATTACAGGTGT GAGCCCCTGCACCTGGCCATATATTCTTAGAAATGAATGAAAAAGCTGCTTAGCTAGATC ATATAGTTTAACTGAAAGTCACAAAGCTATTAAATTGTGAAGAGACCTTTTGACTTCAAA ATTTCAGTCCCTATACTCCCTATGGGAAGATAGTCTAAGTTTGAAAAACGTGTATAATAT ATACTTATATACTGCATATGTATACATATACATAACATAGCCATGTGTGTGTTAGAAGAC AAAGCAGAGAGGGAGTATAAGTAGTGGGAGATGATAATATGGAAGACAGAAGATGAGAGG CAAGAAAATGATAGGTCTCTTAAATTTTACTGTTGATAGTATCAACAGTATTCACTTTGA AAATGGTGAATGAGAGGAATTTAGGATGATGGCAGAGAAATAATAAAAAGAAAAGAACAC ATAATCTATATCAACATTTGACCTGCAGCTTCATTTACTAAGCTTTTACCTATAAGTGTA CATAGTCATGTAATTTCTTAGTTACCTTATGGCTTCTTTTCCATGGAATTCTGGAGACAC CGGTTCAAAAGAATCATCAGAGGAATGCTCAGGATTTATTTCATTCTCAAAGATTTCATG ATGAGTATTTTGATGTTTGGACCAAAATGAGGACTTAAGGAAAAATAATGGAGAATCCCC ATGGCCATCTTTATCTAATTAATTAAGATACAATTACATATTGCATCAATTATACCACAC CAATAAAAAGGGACATCTGTCCTTTACTTGATATCAATTTTGAACTTAAGTTATTTATCT TGGGCATTTATATTTATAATTTTTTTTTTTGAGACAGTCACGCTCTGTTGCCCAGGCAGG AGTGCAATGGCACGATCCTGGCTCACCGCAACCTCCGCCTCCCAGGTTCAAGCGATCTCT CCTGCCTCAGCTTCCCAAGTAGCTATTACAGGCACCTGCCACCACGCCCGGCTAACTTTT GTATTTTTATTAGAGACAGGGTTTCACCATGCTGGCCAGGCTGGTCTCGAACTCCCAACC TCAGGCGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGT GCCCGGCTATAATGTTAAAAATAAAGCATTACAGGTGCATTAAAGTTAAGACAGTGCTGT GGCTTTCGATAAGTTATCAGCTATGATTGACAAAAATAAAAGAGCTCATGAAAGGGAATA CAGTTCTAGCTGTAGGGAATCATATCAAACATCAAGAACTTCACTTTTTGGATTTCCAGA CATTTGGATGCTAAAAAAAGGGATGTGTAAGCTGATCCTGCCATAGCATATGAAGATATA TTATTTTGATAATATAGAAAAAAACAAATATTGAAAATAGTGAGTATATAATTCACTGTA AAATAAAAGAGAACTTTTTTCCAAGTCCTAAGAATACAACAAAAGCACAAAAATGAACAT ATTAAGAATGTTAAGGTAGACGTAAGGCTGGACAACTGTTGTCAAATAGGAAAAGGACAT AGAAAGGAAGAAAATTAAAATTAAAGGATCAGATGTAGGAAGCATGGGAAATTTTTTTAA TTCATTAGAAAAATTAAATAAGCACAGATTAAATTGTTTCTGCCACAAGTCTTCTCATGT TTTATTTTATATAAATTTTTTTCAACCAAATACATAGATAATTCTTTAACGTTTTATGAT CTGGAATTATACAGGGATCTTTATCAAGAGATAGTTCATTTCATTCTCAGGTAGAAGGGG CTCTATGTATAATCAATTAAAAATGGCTTGACAGTTAAATGGACATATCTATTAGAGTAG AGAATACAAGTGCAGATCTAAAGAAGGAAAGAAAATAAATGAGATGGTGTTTTAATGATA TATCCACAAAATAGGAATTTATTGGTGGTAAGAGGAGGAAATTTAAAAGATTTTTCAGAA ACTGTAGGATAATTAAAACAATACAGAATTTTCACATGTAATATTTCACTGCAAGCTGTT ACTGAAAGCTAATATAATGTAGGGGGATGGAGCTGAGCAAAAGAAGAGCTAAGGAAGAAG AGACACAACATATAAACTTCTTGATGTATGAAAGCAAAAGATGTTGATGACATGTAGAAA AATATATGGGAAAGAATGGAAAAGTTATAGATAGAAATTCTTTGACAAGAGAAATGTAAA TAGTATTGCAGTTTTAGAGATATTATGTGGGAGAGAAGAAATGTTCAAAGATGAAAATAT GTAAACAGATCTAGAGTTGAACTAGCCAAAAAGAGAAATTACACTATGAAAAAACAAAGA AAAAATTTTAGAAGGGGAAACAAATTAAAATTCAAAAATGAATTCATTTTATTCATAGAA ATTATAGTATTTTTAAAAACATATCAAAAATCAAACTAATGTTTTATATTCTTGTTTTGC TACTACTGTAGTTATTGCCTGTCCTGGTCAGTGCCTCACCCCTAGTAGCCAAAGCCGGAA ACCAGTGAGCCATCCTCATCTCTTTTCCCTCTCACTTCCCCCAACTTCTACATAATTAAC CACCAAATCAAATTTCTATTTCCTAAGAACCTCGTGAATCTGTTCTCCCCTCTGCATTAC AATGACATCTTAATTTGATCCTCTCAAACAGATTAGTATCCACCTGCTTTGAGCCCATTC TTCATGCAGCTGCCAGAGAGAGCTTCCTAAAAGGCAAATCTCACCAGTGAAAGAGCCTAC ATACACTACTACTTCAGTCTGTCTCCATTTTTTGCACCAGTCGTTCTAATGCTTTTGGAT TTTTTGTACAAACGATAGTTCAAGAAACAAATATGTTGTGTTAAGGATAGTTTAAAAGCC TATCTGCTATGCTATAACCATCACTGCAAAAATAAAATGATATTTTTACTACAAAATACA GATAGAGAAAAGCTATGATCTCACAATAGAGAAGACAATTTCAAATTGAAGAATTAAGGT ATATAAATAAATTTCACATTCTTTCTCTTATCTGACAAGGTGAAAATTTTGTCACAGATC ATCACCAATACTTGAGTTGCCCAAGAGGACACAATCCAAAATTCTGTACATTCCCTATCA AGTGAAAATTATCACCAGGCACCTATAGAGGGGCTTAATTGGAGACAAGCCTCAGAATCT CAGGGATCTTTACATGCTATATTGTCCTGTGCCATGTACATTTGGAAAAATCTCCCGGTA ATTATTGTAAACTGGTTAATAATTTCTACATCACAGACTCCTACTATGCACCAGCTCTGC CAAACAATTTTTAATTTCCCTTATGATATACTATTTCACGTTGCTGGGCATACATGCTGG TGACTATATGGCTGGATAACTGTTGTCAAATAGGAAAGGATATAGAAAGGAAGAAAATTA AAATGTGTTGCTGGGCATACATGCTGTTGACAATATGGCTGTGGACAAAATGTGTTTTCA AGACTCTTTAAGATGATTTGTTTTTAAGACTCTTCTCCACAAGATAAACTTACCTATCCT CTAAATGCAATTTGAGGTGTTTCCTCCATGCCTTTTCTAATTTGACAACCCTAGAACTTA CCCTCTCATGGAACCTTGTGGTATCCTCTTATTATACTTCTTACACTACATTTAACTACC AATTTACATAAGTATTTCCAATGCTAACTGCAAAAGCCTTGAAGACTCAGACTGTTTAAC CCATCATAGGCTTCAATAAGCAGTTACATTTTAAATGGATAAGTAGATTAAACCTGATGT CTAATTGGTACAGATACCATTAGCAATTCTTGGCTTGTTTTGGTTCAGTAAAAGAATTAT AAGTGTAAAAACATTTACATATAATCTGGTCTAAAAATAAAGATTTGAAAGATGCTTATA AAAATTTAGATTGACCAGGCACAGTGGCTCACACCTGAAATCCCAGCACTTTGGGAGACC AAGACAGCTAAATGGCTTGAGGCCAGGAGTTTGAGACCAGCCTGGATAACATGGCAAAAC CCCGTATCTACAAAATTACCAAAATTAGCTGGGTGTGGTGGTGTATGCTGGTAGTTCCAG CTACTGGGGAGGCTGAGGTGGGAGGATTGCTTGAGTCTGGGAGGCAGAGGTTGCAGTGAG CTGAGATTGTACCACTGCACTCCAGCCTGGGTGACACAGTGAGACCCTGTCTCAAAAAAA TAAATAAATAAATTAGATTTAAAAATACGTATTATACCCAAATAAAGGTAAGTGAAATTT AATCAAATGTAAGGACTTTAAAAAAGAATTTTAATTTGAAGCTGAGAGAGAAAAAGAGTT CATTCTTGCCTTACTTCATCAAATATTTATTGAGAGCCTCCTATACACAACGTAGCCTCT AGATGGAAAAACACACTTTGTTCATCCTGAATAAAGTTCAAATGGAAAGGCACATATATG CATTTATTTAATTTGCTGGGAATTTATTGAGCATCTACTAGGTGCCAAACACTGTTGTGA TGCATCAGTGTCATAAAAAGCAAATATCTCTTCCCTTGTGGGGATCTACATTCTAGGGAA ACAAAACAGAATAAACAATAAAATATTCAATTCTATTAATATTTAAAAAGAAAGAGCATT AGGTCAGAGTTTCAAAGTTCTAGTCCAAATTCTGCTAAGTGTGTTCTTGGCCAGTCATGC AACTTCTCTAGATCACTGTTTTGGCACCTCTAAGATGTGTGTTCTGGACTAAATAATGAA CTAAAAGCTGATTATTAAAATTATAGATTATACAAACAGGAATTGAAAAGAAAAAGTCAA ATTCAATTTTCCCAGGTTTAAAGATTACTTGTGCTTCTGGGCAGTGGGGCTGGGGGAATA TTGGAAAAGAAAAACAAGATGACTATGAATAAGTGAAGGACTTAAAGAAACATGAAAATG TTGCCTATTAAAAGCTAATTAAAGTCTAGAGATGAGGAATTTGTGTTACCATATTAATTA TCAAAAAGCTCTCAGTTCGATGTAAAACTTGTAATTCTAATCACAACAGAAGATCATGAA GCGGAAATGGTAAAAGCACAAATGTAATATCCCTAGAATTACCATAAGTCTGGAGTTTCT ATCTTTATAGCTAACTGTTATAATTGAGCTTCATAGTAGACAGAATTTGAGCATACAATG TCTGTGAACAAAGAACATTATTGTTCTTATTAAAGCTTAAAAACCCATCATCATGTTGTA GAAACTTACATTAAATTTAGGACCTCCAGAAATTAGGTAGATACAAATGACACAGAAAAT GTGATTCTAGAATAATACTTTTCTTTTAAACAATATATTCTATGTAAAATTTGTCCCCCG ACATGATCAGAGGTATCATTTAAAGGAAAAAAATGAAGTTGGTACAGCAGACATCAATAA GGTGTGGAATAGGACTTCCCAGCACTTGTTCCCCAGCAGAAACATTAACTTGAAATGACT ATCTACACTCAAAAATACCTTCACAAGCGCTAAGGAAACCAGCTGACAGAGTACAGCACC TGAGTGTAGTAGATCAGAAGCAAGAAAAGATGCATTGAAGAGGGCAGAAAGGACAGTTTT ACAATACCTGTGCCACCCCTTCCCAACCTGTCAGGCAGCACAGCATGAAAAGAGATACTC ACCACTTGAGGAAATGAGAGATTGTTTCCTGTCTGTGCAAAAGCATTTTAGTTTGATGTA GACTCTGTCTCACACCATATACAAATTGGTCCCAACTTGCAAAGCTTCAACTTATGATTT TTCAACTTTTCAATAGATTTATTGGGATGAAATGCCATCATAAGTTGAGGAACATCTGTA CAAAAATCAACTCAAAATGGAGTAAAGACTTAAAAGTAAAACCTGAAACTGTAAAACTAC TAGAAGGAAACGGGGGAGAGGGGAGCTTCATGACACTGGTTTGGGCAATGATTTTTTTGG ATAGGACCCCAGAAGCATGAGCAACAAAACAAAAGTAGACACATGGGATTACATCAAACT AAAAAGCTTTTGCACAGCCAGGAAAGGAATCAACAGAGTAATTAGAAAATATTTGCAAAT GATACATCTGATAAGAGGTTAATATACAAAATATACAGCAAACTCAATAGTAAGAAAAAA TAACCCAATTTGAAAACGAGCAAAGGACCTAAATAAACATTTCTGAAAAGGAGACATAAA AATGGCCAAGAAGAATATGAAAAAGTACTCAACATCACTAATCATCAGGGAAATGCAAAT TAAAACCATAACGTGATAGCACCTCACATCTCTTGCAAGGGATGCTATCGAAAAGATGAA AGGTAAAAAGTGTTGGCAACGATGTGGAGAAAAGGGAAGCCTTGCCACTGTTGGTGAAAA TGTAAATTAGTACAACCATTATGAAAAATATGATGAAGGTTCCCAAAAAGGTAAAAATAG AACTACCACATGATTGAGCAATTACACTTCTGGTATACATCCTAAGGGAAGGAAGCCATT ACACTGAAGAGATATCTGCACTCCCATATTCGTTGTAGCATTATTCACAATAGTCAAGAT ATGAAAACAACAAACCCAGTGTCCATCAATGGATAAATGGATAAAGAAATTGTGAGATAG ATATATATATATATACAATAGAATACTATTTAGCTTGTAAAAAAAGGAAGGAAATTTTGT CATTTGTGACAACATGCATGAACCTGGAGATACATTATGTTAAGTAAAGTAAGCCAGATA CAGAAATATAAATACCATATGATCTCATTTATATGTAGAATCTAAAAAGTGGAACAAACT GAAATAAAGAATAGAATCTTGGCTACCAGGGCCTGGCAGTGGGTGGAGAGAGAGCAGGGA TTGGAGAGGTTGGGAAGATGTTTGTTAGTCAAAGGATACAAAGTTTTAGTTAGATAGGAG GAATAAACTCAAGAGACCCATTGTACAACATGTTGACTACAGCTAATAACAACGTATTTT GAAAATTGCTAAGAGAGTAGATTTTAAGTGTTCTCACTACAAAGAATAAGTATATGAGGT AATGGATATGTTAATTAGCTAGATTTGACTAAGTTCACAATGTATACTATTTCAAAACAT CATGTGTACATGGTAAATATATCAAGTTTTTGGCAATTAAATTATTTTTAAAAAGGTTTT GTGGTCAATAAAGTATAGAGACAGTGAATTACTAATTAAATTTTATAAGAATGTATTAGG AGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAG ATCAAGAGGTCAGGACTTCAAGACCATCCTGGCTAACACGGTGAAAGCCCATCTCTACTA AAAATACAAAAAAATTAGCTGGGCGTGGTGGCAGGTGCCTGTAGTCCTAGCTATTCGGGA GGCTGAGGCAGGAGAATGGCGTGAACCCGGGATGTGGAGCTTGCAGCGACCAAGATCGCG CCACTGCACTCCAGTCTGAGGGGACAGGGCGAGACTCTGTCTCAAAAAAAAAAAAAAAAA AAAAAAAGAATGTATTAGGAAAAAAATTATGTTTACTACAGAAAACCAAAAATTTAGTAT GGCACAGAATTACAAAACAGAAAAAATTTAACTTTGGCAATATACAACTTATTTCTTCCT CTACCCACTACAAAAAATTCTCATTTTGTCTGCTAGGTTCCTGGGCTTTGGGGGCTAAAG AAAATTAATTTGATTTATATTATAAAGGATAACGAATGATGGACAAAGGATAAAACAAGA GATTCCAAAAGGAAGAAAGCAATGAGAAAGTAGAGTAGAGCCTAAACCAATTAGTTGAAG GACACTTTTAAGAATTTAGATGCCAGGCACAGTGGCTCACATTTGTAATCCCAGCACTTT AGGTGGCCAAGGTGGGAGGATCCCTTGAGGCCAGGAGTTTGAGACCAGCCTGGGCAACGT AGCAAGACCCCACCTCTACAAAAAAATTTTTAAAAAAATTAGTCTGGTGTGGTGGCACAT GTCTGTGGTCCCAGCTACAGAGGAGGCTGAGGTGGGAGGATAGCTTGAACCTAGGAGGTC AAGGCTGCAGTGAGCTATGATGGCACCACTCCACTTCAGCCTGGGTAGCAGGGAGACCCT ATCTTCAAAACAAATAAAAAGAATTTAAAGAACAGGGTGTTTTTAATGCTCTTGCCATAT GTATAAGTGACAGAATGAGTGCATACAGAAGTAGACAAGGTTTGGGATTTCAAGTTCCAT TTTGCCTGTTTGAAAAATAACATTAAAGTAATTTTTTAAATTATCAAATATGAGAGTGCT TTCACTGTGATCTGTAACAAGTTAGGGCAACATGTTAAGATAATTTTATGTGGGTTATGT ATGCTACATGCTGCTCTTTAGTCAAAAGAAGAAACTTTATCTAATTAGAGAATTCAATTC ATTTCTTCACAGGAATAATTTTTCAAAGTAATTTTGAAGCCAATTTGCCACATACATAAG AAATTACTCATATGAACATGTTACATCACGAAATTGGAAAACTGTATTATTTGCCAGTAA GAAGCATAGGGACTAAACTGTAAACGATAGTACAATAAAGATTAAGCAAATATAAAATAA GTCTAGAAGAAAGCTATAAATATTTTTCAAATAAAATACCTGAATTAGAAATCAGATGAA CATACTAAAATAAGTAGGGTTTGAAAATAACAGTAATAGTCAGATTCTGACATGTAAGAA ATTATGTGTGAGGAAAACATAGATTTTTTATGGAGCTAAATAAGTACAGTCACGTGTCAC TGAACAATGGGGATACCTTCTGAGAATGTGTCATTTTGTCATTGTGCACTCTACAAACCT AATGATATAGTCTACTACGCACCTAGGCTATGTGGTAGCCCATGGCTCCTAGACTACAAA CCTGTACAGCATGTTACTGTACTCTATACTGTAGGAAATTGTAAGACAATGGTATCTCTA TCTTATCATATCTAAACATAGAAAAGGTACAGTAAAAATATGGGATTATGATCTTCTGTG ACCACTGTGGTGTCTGTAGTCCATCATTGACAAAAACATTGTTATGCAGCACATGACTGT ACATTAGGTTTTAGGATTATATGTGCACACACTATCTACAAATTTTATAGTCATTTAAAA GCCATCTGTAGAGCTTATGCTATTACTTTATTATTATTATTATTATTATTATTTCAATAG TTTTGAGGGAACAGGTGATGTTTGGTTACATGGGTAAATTATTTAGTGGTTATTTCTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCCGGAC TGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCTTCCCGGGTTCACGCCA TTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCGCGCCCGGCT AATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGATC TCCTGACCTCATGATCCACTCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGC CACCGCGCCCGGCCTTTAGTGGTTATTTCTGAGATTTTGGTGTACACATCACCTGAGCAG TATACACTGCATCCAATGTGTAGTCTTTTATCCTTCAACCCCTCATCCTTCCCTCCAAGT CCCCAAAGTTCATTATTCACATGCTTTTGCATCCTCATAGCTTAGCTCCCACTTATAAGC AAGAGCATATGATGTTTCGTTTTCCATTCCTGAGTTAACTTCACTTAGAATAATGGTCTC TGACTCCATCCAGGTTGCTGCAAATGCCATTATTTCATTCCTTCTTATGGATGAGTAGTA TTTCATTATATATATGTATATATATACAATGGCATATATATACATATATATATATGCCAC ATATTTATGCCACATATATATATATATATATGCCATATTTCCTTTACCCACTCATTGATT GATGGGCATTTGGGCTGGTCCCATATTTTTGCAATACCACTTTACTCCTGCAAAATTGCC ATAATTTAAAAAATCAAAAAAGAATAGATGTTGGCACAGATGTCGTGAGAAGGGAACACA TTTACACTGCTCGTGGGAATGTAAACTTGTACAACCACTATGGAAAACAGTACGGAGATT CCTTAAAGAGCTAAAAGTGGAACTACCCTTTGATCCAGCAATCCTACTACTAGTTATCCA CCCAGAGGAAAAGAAATCACTACATGAAAAAGACACTTGCATATGAATGTTTATTGCAGC ACAATTTGCAATTGCAAAAATAGGGAACCAGCTTTAAATAATGCCATTATTTCATTCCTT TTTAATGGCTGAGTAGTATCCTATGGTATATATATATCATATATATACATCATATATATG ATATATATATATATATATATATATATATATATATATATATATATATACACACACACCACA TTTTCTTTATCCACTCGTTGGTTGATAGCATCTAATGTTCATCAGAGATATTGGTGTGTA GTTTTCTTTTTTTGTTATGCCCTTTCCTGGTTTTGGTATTAGGGTGATCCTGGCTTCATA GAATGATTTAGGGAGGATTCCCTCTTTCTCTATCTTTTGAAATAGTGTCAATAGGATAGG TATCAATTCTTCTTTGAGTGTCTGACAGAATTCAGCTATGAATCCATCTGTTCCTGGACT CTTTGGGGGCGGGGGGGAATATTTTAATTACCATTTCAATCTCACTGCTTGTTATTGGTC TGTTCAGGGTTTCTATTTCTTCCTGGTTTATTCTAGAAGGGTTGCATATTTCCAGGAATT TATCCATCTCCTCTAGGTTTTCTAGTTTTTGCACATAAAGGTGTCCATAGTGGCCCTGAA TGATCTTTTGTACTTCTGTGTTATCAGTTGTAATATCTCTCATTTCATTCCAAATTGAGC ATATTTGGATCTTCTCTCTTTTCTTGGTGAATCTTGCTAATGGTCTATCAATTTTGTTCA ACTTTTCAAAGAACCAGCTTTTTGTTTCATTTATTTTTTGTATTTTTTGTTTCAATTTCA TTTAGTTCTGCTCTGATCTTGGGGATTTCTTTTCTTCTGCTGGGTTTGGGTTTGGTTTGT TTTTGTTTCTCCAGTTCCTTGAGGTGTGACCTTAGATTGTCTATTTGTGCTCTTTCAGAC TTTTTGATGTAGGTATTTTATGCCATGAACTTTCTTTTTAGCACTGCTTTTTCTGTATCG CAGGGGTTTTGATAAGTTGTGTCACTATTATCATTAGGTTGAAAGAATTTTTAAATTTCC ATTTTTATTTCATTGTTGACCGAACAATCATTCAGGAGCAGGTTATTTAATTTCTGTGTG TTTGCATGGTTCTGAGGGCTCCTTTTGGAGTTGATTTTCAATTTTGTTCCACTGTGGTCT GAGACAGTGCTTGATATAATGTTGATTTATTGAGACTTGTTTTGTTGCTTATCATATGGT CTATCTTGGAGAATGTTCCATGTGCTGATGAACAGAATGTATATTCTGCAGTTGTTGGGT AGAATATTCTGTAAATATTTGTTAAGTTCAGGGTATACTTTAAGACCATTGTTTCTTTGT TAACTTTCTATCTTGATGACCTGTTCAGTGCTGTCAGTGGAGTATCGAAGTCCCCCACTA TTATCGTGTTGCCATTTATCTCATTTCTTAGGTCTAGTAGTAATTGCTTTTATAAATTTG AGAGCTCCAGTATTAGGTGCACACAGATTTAGGACTGTGACATTTTCCTGTTGGACTAGT CCTTTTATTATTATATAATGTCCCTCTTTGTCTTTTTAACTGTTGTTGCTTTAAAGTCTT TTTGTCTGATATAAGAATAGCTACTCCTGTGTCCATTTGCATGGAATATCTATTCCCACC CCTTTACCTTAAGTTTATGTGAGTCCTTATGTGTTGGGTGAGTCTCTTGAAGACAGCAGA TACTTGGTTGGTGAATTTTTATTCATTCTGCTATTCTGTATCTTTTAAGTGGCACATTTA GGCCATTTACATTCAATGTGGGTATTGAGATGTGAGGTACTATGCTATTCATCATGCTGG TTTTCTAGAATGCTGGTTATGCTAGCAGTGAAGTTGCCACGTGGACAGACTCAGGACCTC TGGTTAGCCAGGGTGTTGCAAGTGGTAGAATTATCTGTTGTTTTCTCCTTCTTTGGTGCA GGATTGTTCTGTTATGACTTTGTGTAATGGCTTGAGTTCATTGGCCTCCAACCAGGAGGT GGAACTTTCAAGACAGCACCAGCTGCTGTAGCGCCCTACAGTGGCCAGGATAAGTACTCT GGTTTCTCAGGCTATGGGTGGGGCCATAGAGCTCCCAAGAGTTTGTGTCTTTTGTCTTTA GCTACCAGCGGTGGGGAGAATAAAAACAATCAGGTGGGGGCAGGGTTAGGCATGTCTGAG CTCAGACTTTCCTTGGGTGGGGCTTGCTGTGACCACTGTGGGCGACAGGTTTGCGGGTGG GGGGAGGGTCGTTCTCAGACCAACGGTGTTATGTTCCCAGGGGAATTATGGCTACTTCTG CTGCATCATACAGATAGCCAGGAAAGTGGGGGAAAGCCAGGAGTGACAGGCCTCACCCAG CTCCCACACAGTCAGCAAGGCCAGTCTCACTCCCACTGTGCCCCCACAACAGCACTGAGT TTATATTCAGGCATCCAGTGAGCAAGGCTGAGATCTTGCCCCAGGCTATAAGCCTCCCTG CTGAGAAAGCAAGCAGGGCTCTCGGGCCTGGCTGGGCCCTCCCCATCTGCCCACACCTTT GGCTGTTGCTTCTGCGCTAGTACCTACATTTCCTGTTCAACCCCCTAACCAACCCCCACC CTGGCCCCTTCCGATTCTGCTCAGGAAAATTCATGCTCAAAGTTATTACAAAATTCAGCT AGGAGCTTCCTTCACTCTGTGGCCCCTCCCCTATTTTATTACCTTTAATAACATTATAGA AAGCATTCTTATTGGGCTGATGTTTCGACAAAAGGGAGAGAATAAGAAATAATCCATTAA CTTCATATTGTGTTTCCTTCTTCATATTTTTGAGATTCGGAAGAACAACTATACTTGAGC CAAATATTAACAAGAACCAATTAATGAACTATTTTACATAAGTGAGTTCAATTTAGGCAC TAAAAAGCATCATTATTCAATAGGTGATTTAAGTGTTTTCCTCCCTCTCTCAAACTAAAA CACATACCGACACACATACATCCTACCTTTACGAAAGACAAAAACCAAAATAAATACAGT TCTTTTTAATTAAAATGATTTTTAAAAATGATTCAGTTCGGCCGGGCGCGGTGGCTCACG CCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAG ACCATCCCGGCTAAAACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGG CGTAGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTG AACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAGCCTGGGCG ACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAATGATTCAGTTCATACCTTTAAATAGT AAAATGGAAATGAGGAAATTCTATTGTTTTGAAATTTTTTCTTCTCTACTATCAGAAATG CTTCTTAAGTTACAAATAAACAGATATTAATACATGTTTTAAGAAACAGAATTGCTTTAA ATTTAACTTTAACCACACTATTAACTTACCAGGTAAAACTCGCTCAAAATATAATGTGAA TATCAAATAGAAAAGAGTATCAAATGCCAAAATGAAAAAAGTGGCTATCATTTTGTATGA ATCCCCAGAGGGATCAGGAAAAATAACACCACTTAAGTAATTATCCAGGTGTGTAATCTG AGATTTAAAAGAAAAAATAAAATGTTAGATGAACTTATAAAACTAAATAAAACAATTTTT TTTAAAAAATAGTGGTACCTAGAGATATGTAATTAATATTTTAATACCTTTTCAAATATG CATAGTAAATGTGCTATTAGTATTGTTGCTTTTTAAAAAATGTAAGTATTCTCACAAAAT TTTAAAATGCTATATATGAAAGTAAAACAAAAAAGAGAAATTAACTGCATCATTAATCAT GGGTATTTTAACAAAGAAAATATGGAGAAGTGGACAAGCAACCAAATATAACATACTTTG GGAAGGAAAACTTGAAGTGGGCAACATAATTAGAGCCCATTTAAAGAAACATAAAAATTC TAAGTATAAGATATTGCAGAAACATTCAATTATTAAATAAGTACTGAAGACTTGAAGAAA AAACTAGAAAGATAATAATGATAACAGTTAACATTTAGATAGTATGTATCTGGCTCTGTA CTAGTGCTATATGTATATAATAGCACAATTAATCCTAAAAATTTACCCCCATGAGGTGGG TTCTACTGACATCCTCATTCTGCAGAAGACAGGCTAAAGAGATTAAGTGACTTGCCCAGT GTCACCAGCTGGTAGGCAACAGAGATGAGACCCTTATCCATGCCATCTGGCTTCACTCGT TATTCATAACCTCACATTTTACTGCCTCTTTAAAGGGGGACACAAACCAGATATTTCTCA GTGGTCAGATAATGGGCAATTATTTTTCTTCTTTAAATTTGCTAGGATTTTACAAATGAT CTGCCTGCTTTGTTTATCCATTTGATAAAACTTTTTTGTTGTTCTTATTTAGTTTCTCAA CAGCAGAATTTCTTAAAACACAGAGTGGCTGATTATTAAATTTCATGAGGCACCAAATTC TTGAATAAGAACATATTTTGAAAATCTAATAATAAAATCTTGAAATAATTATGTTCTTAC CTGGGCCATTCCAGCAGTGAAGGCAAAAGGGCTAAGAAGACTTAATACCCATCCCAAAGA TAAAGGAAGTTGTCTATATAACACAGTGAATCCCAGACATCCCCAAAATACAGTGAAGAG AAATCCAGCCAAACCAGCGAGCATAGGTTTCCTTATTAAAACACTCATGAGGAAAGCCAA TGCTATCTGAAGGAAGAAAGAGGTCTGATTGGTATATTTTTCCTTGAAGATTCATAAATA GCAATATTCATCGATTTCTCACATTGTCAAAAATTTTCTCAAAACATATAGAAAATAGGA TAGAAAATATAGTGATTACACTAATATCCCAAAGAAACATTATTTGCTCATGTATCTGTA ATCTGAAACAGGTTAAGAGGTAATATGCTTTTACCAACTCACCAAAGAAAGGCCATATAA GCTATAGAGTGTGAATATCACCATGAAGCCAGTATGAAATACAATTGGGATTGATGTTAT GACCAGAGCCATAAAAATGGACATAATGAAGATGAAGCAAATGTATGTCAATCCCCAGGA GAGCCTATAGTAGAAACAAGGTGTTAGTTCAACTGTCACAAACATAAATGTTTGGAGAGG TAATGTGCGAAATGGTTAAGAGTAAAAGCTCTGAAATCAGGACTAAATTTATTCTAAATG GGTGGCCATACACATTTTGTGACTATTAGCAAGTTATTTATCTTCTCTCACTCTCATCTG TAAAATGGAGTTTTTCATGGTAGCTATTCATATGGTTGTTCTGAGAAATAAATGAGATAA TGCTTTTGAAGATGTTAGTTTAGCATGTGGCACAGAAAGTAGCCATTACTATAATTACCT CTATAGCTGTAGAACAAATTTTATATTTAATATAATTAAATATACTTTTATTCTTTCAGT TAAATGACTATATAAAATGTCAGTGGAAAAACAACGACAATCTCCCCTTTAAACTTCCTT ATACTAAAGCTTTCTAAGGTATACCATTCTTCTGAATGTTTAACAGAAATCTTTCCAATT TAAGTAAAGCTCATTTCATTTTTTATCCTTGTATGGCTATGGACATTAGACAATGTATTA TTTTTAAGAATCAGAATACCATAGTGCTATTAAGAAATGTGAAACTAAAATAAAAGGAAA GGTATTATGATGCCAGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGTTGA GGCAGGTGGATTGCCTGAGTCAGGAGTTCGAGAACAGCCTGGCCAACATAGTAAAACCCC ATCTCTACTAAAAATACAAAAAATTAGCTGGGTGAGGTGGCGGGCACCTGTAATCCCAAC TACTAGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCAGAAGTGGAGGTTGCAGTGAGA CAAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCATCTCAAAAAAA GAAAAAAAAAAAAGGTATCATGATGATTATAGTTGTATAACTGTGATTGAATGTCGGAGT AGCCAAAACATTGTTGCTTTTGAAAATCTCTGGAAGTAGATGGAAAGGTATGTTTTAAAC AACCACCACATGATCCAGCAAATATACCACTGAGCATTTTTCCCAGAAAAATTAAAACTT ATGCTCACACAAAAACCTGTATATGAATGTTAATCACAGCTTTATTCATAAATGCCAAAA ACTAGAAACAACCCATATCTCCTCCAAAGGCTGAAGAATTAAACAAACAGAAATACATCC ATGCCATGGAATAGTACTCAACAATAAGAAAAAACAAGCTATTGATAAATGAGAATTTGG CATACTTGAGCCTTATTTGGGCAAAGCAGTACAATCTACTGAGTTAAGTAGTAAATTTGT GCCTGATCAGATAGAAAGTAGAAGGGATAATATACAAGAAGTGTGAGGGCTTTACAAGAA ATATAGCAGTTTTACCTTAATACTTGGGATACTTGCATTTGGCAATGGGTTCTTATAAAA ATTTAAAGACCAAAATTCACAAAGCTATATATTTTTAAGAAAATTATATCATTTTATTAT TTAAAAATCTATTTTCCTTGTCTTTGAAAAGAGGAGAAAGAGCTTGTCTAAGACACCCTC CCCAATAACAGATGCAACATATCAATTAATAAAAAAATTATATCCAACACAAAATCTGCT ATCTTGTACCCTTGTATGGTTTTATATCAGGGAAGAATCATTCAGAAATTTAGATTAAAT GTTTGAGGTAATGGATATTCCAATTGTTCTGATTTGATCATTACACACTGTATACATGTA TCAAGATACCACATGTACCCCACAGTATATACAACTATGATGCATCAGTTAAAAATAGCA AAAAAAGGAAAAACAAACCTGAATCCAAACTTAGTATTTACCTACCGTAAAGCTAATAAT ATGGTATGCATTTCTGTAGGCCAGTTTCACAAAAGGCTTTTTCTATCTCCTTTTCCCCCT TGTCATTAAATTTATTTTATTAATATTTTTGAGTTTTGTAGCACAGTCTCTAAAAGAGTG CTGTTTTCTTAGGTTTGATTTCTGGCTTTATTGTTTATAAGTTATAGGTTTTAGGGAAAA ATCTTAACTTTTCTCTGCTTTATTTTTCTTACCTGTAAAATGTGGATAATAGTTCTGTCA TCCCTAGAACACGGTAAAGTACTTAAACAATGTTCATTATTATTTCTATAATTATTAGAC TATAATACCTCATTATTATTAAATATTTATTACTATAATTGTATACTATCTCAAAGTCTA GGGGAAAAGGGACAATACTTAAAGGAATGGATGAATGCATAGATATATATATAAATGCAT AGACTATATAGATGGAGAGCATAGATATATATATAAATGCATAGACTATATAGATGGAGA GAGATGTCTTTTACCATGCACTAACAAACACCGAACACTGTTTGTGCTGTGTGATTTAAA CATATTGCCTCATTTAATCCTGATACCGTTTGATGAATTCCAACCAAATAACATTTTTAC AGACTATGTGACCGGGCCTCAGTGACACTGTGGTAAATTCCTTTATTGCCCAAAATTATT TGAACTTTTTTCTGCTCCTCACTGTTATGAAAAGCAGCATAATTTCCCATGTCACTAAAT GTGAGGTTGTCACTTTGACTAGCTTTGACCTCATGGTGGGCAGAACACACTTCTTCCCCT CTTGACTTTAGTTCTGTCCATGTGACTTACTTTAATGAGATTTTATTATATATGATGTGA GCAGGAGCTTGAAATGTGCTTGTGCAGAGAGACTTGCCCCCTTGTGTTTCTGTGATTGAA TGAGAAGACCATGGCCAGCTAGCCTACTGGCCCAAGAAGGAAGTGAGTCACAGGAAGAAC ACCTGGATCTAACCTGTACCTTGAATCCAAGCCTGGCCAAGCCCAGACTAGATCTGCCAA AGTCCACCCATACTGCAGACAAATGAGAAAGAATAAATAATTGCTGCTTGAGGTCGTGGG GTTTGGGGTGGTTTTTATGCGGCATTTTTCGGGCAATATGTAATGATCACATATTTTTCT TCAACTCAGGGAAACATAAGCACAATCCTTACTTACTTTCTACTGCAAGCATCTTAAACT CTAATGCAAGTAAGGTGATTAAATTGAATACGTGCAAGAAAACTTGTGAGTGCGTCCAAT TTTTTAAGAACCTAGTTAGTTTCTCTAATAATTAATGTATGATATACAGTAAAGTAGCAA CTTAACTTACCAGAATGCTGACTCTCGGAGACCCATCACTGTCATCAGTTTCTTAAATTT TCCTCTTTCCCTTGCAACATTTAATGATGCAAAGTATATAAAAGAAGAGAAAGAAACTAA GCAAGTAAAATGAAACCATTCATTCATAATTTCTCCCTTAGAAATGAAAGGTGGTATCTT CATATTTATTCCAATAACTGATGTCAACTCCTCCATTACAGAATGATTTGTTGTGACCTA AATTGGGACATTAGCAAATTTATTATGTGAACTATAGACAAAATATATTAGAAAACTATA CACTTTTTATTTTCGATTTCAATATTTACATATTCTCATCATTTTAAAGTATGAACTATT AATATCAGAACAATCTTAATAACTTTTGATACCAATTGACATTAATTATAAGAGTCATTT GAGAAATTACTGAAGGTCTGTCATGCATAATATACTGTGCTACGTAATGGGGAAACAGCA GCAATTCAAACAGAAACACTCTTCATTCTCATAGAGATTTACATTTTGTAGCGCAGCAGA AGAAAGGAGAGATATTAAATAAATCATTGCATAATAAATTGTTTAGTTACAATTGAGCAA CTATGTTCAAAGAAAAGTGTAGGAAAATCAAGAAAGGCTTCCCTAAAGAAGTGACATTTT TACTGAGTGTTGAAGGCTGTGATCTTTCCTAAACAAAGATTGGGGGAGGGGGGGTGGTTG AGGATGGAGAAGAAAACTGTGAGCAGAGTAAACAGTATATGAAAAGGAAAGAAGGTGTAT AGTGCGTTGGAGCACAGAAAAGAGGTTCCTGCCACAAAAACAAATAAATAGACTGTAGAT AAGGCTGAAGAAATAAACCACTCCCATAGTTTAGGCAAGATATGATAAAGATGTGCCCTT GTGCAGGTGGCAGAACTGAAGTACATAGATTTGAGCTTAGAAATAAGAGGCCAGGTAAAA GATTGGATGTGATGAGTGAGACAGAGAAAATTTTCTCTGATAATCCCCAGTTCCTTTTAC TCAGCTAGGTGGTTTTAGCATTCACTGAGATAGGGAAAATTTTATAAGACTCAGTCACAT TTACAGAAAAACATCCATGTTCATTTTTGCGCATACTAAGTTTGAATTGCTTGAGACATC AAAGTAGAGGTATCCAGCACACAGTCAGATACATGGAGCTAGAGCAGACGTCTAGCTCTT TTAGTCCCTAGCTCCTTTAGAGGTCAGCAAACTTTAGTTCCCAGACCAAATCTGACCCAC CACCTGTTTTTGTATATAACATTTTATTGAACACAGGCACACTCATTTGTTTGTGTTATC TACAGCGGCTTTCATACTACAACAGCAGAGGTGAACAGTTACAACACATTTGGCCCCCAG AGCCTAAAATATTTACTGTGTGGTCCTTTACAGAAAAATGTTGCTAGTCTACAAGTTAGA GTTCTTGGAGTCATCAGCATATAAATTATAATGAGAAGTACGGGAATAAATGAGACCATC TAGAGAAAACATATGGGATAGAAAGAGATGCCTGAGATAGAACTTTGTGGAACTACAGAT AGAAAGATGTAGGAGTGTAAGGGGAGATAAGTTGGCAAGAAGACTGAGAGGGAAAGGCTA GAAATGGAGAAGGGAAATCAGGTGAATCTATGTTATTTAGTTGAAATATCAAGTAAGGTG AGGAATAAAGAAGCTGTTAATTGACATGGAAGTTGTTATTTACCTTAGAAAAAGCCCTTT TGATGGTGTGGTAGGGATAGATAATATTGAGTTGAGTTGAGTCAAAGGAGGACAACCCTT TCAAGAAACTTAGCCATTAATAGAAGGAAGTTAGGGTAGTTGTGTGAAGAGGAAAGTGGA TAAAGGAAGGTCTTGACCATAAGTGAAGAAATTAATTTTAAATCCTGAAGAGAAGAATCT AGCAGAAAGGCAGAGATTGAAAAGAGGAGACAAAAACAAAAGTCCATAGTTGAACTTTGC TGATGAAGTTGGGAGGGATGGGATCCAGACCATGAACTGAGGAAAGACATTAGGGATGAA GAAAGAGAATGTGTGTAGGGGGTCATAGGTCTGTAGTTTTACAGGGTTTATGTTAGAAGT TGGGAGATATTCCCATGTGACAGCTTTTGTTTTCTCTGAGGATGACAGGCAAAGTATCAC CTCCTAAGAGTGTAAGAGTAAGGTAGGGGATGAGGCAGATATTTAAAAAGAGGGAAGAAT ACAGATTTAAAATATAGCTTTGAAGTTAGGCACTTACTTCTATAATTGCAGCATTAATTG CAGCTTGAAAAGCTACAAACCCTTTTAGCCAGTACTTTGCCAAGTAACAAAAAATTTCAC CATGCATGGCCCAACAGTGTTCTTTAAGGAAGAAGAAAAACATGTCCATAGTTATATAAT GGAGTCAACTCCTGGAATTAAAACTTTAACTTTGGCTCAAAAATCAAAATATCTAAATGT TAGCTCAAAGCCTATGATTATATGATATAGAGGATTTTTAAAGTACTCTACAGAATTGGA GAAAAAAAGAACATATGATGGCAGGGGCAGTGGCTCATGCCTGTAATCCCACCACTTTGG GAGGCCGAGGCGGGTGGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGG TGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCCTGTAGTCCCAGCTACTTTGGA GGCTTAGGCAGGAGAATCACTGGATCTCGGGAGGCAGCGGTTCCAGTGAGCCAAGATCGC GCCACTGCACTCCAGCCAGGGTGACAGAGGGAGACTCCATCTCAAAAAAAAAAAAAAGGA CATATGAGTAGTTGCCAAAATAATGAGACTCATCCTAAGTTAAAGACTGATGATTAAGTT CAGAGGGAAATGTATATTAATTCTTTACTTGGTTGTATTAATATTCCTATCAGTCATTCC AAACAGGGGATTCCATGAAGTATCAAAAAAAAATTATAATCAGTTTTTTTATAGTTACCT GTGTATTCAGAGTGCTCCTTTATAACTGGGATTCTATATCCCCAATTAAACTTCAGGCGA TATGAGAAAGTATCACTAAATATAACTCCCACCATTTCATGGTATTTTTTTGGAAGTTCT ATATCCATGGTCTCTTCATCTGGTGTCCCAATGACTGTTCTTCCTACCATGTATGAAAAA CATAAATAAATAATCATGTAAACTTATTACTAGAGGACACAAAAACAAAATACAGTTGCT TGTTTTATATAAAATTAGTGGTATTATATATTATTTCTGGATAGCTGCCTCTTAGTAAAA GGCTGAGTGAAACTATTGTTTTAAGTTCAATGCAAATACATGAAAAGACACAAAGGACAC ATTGTCTTTTAAAAATCTGCAGCATATTGCTTTTAGTGTGATCTCATTTTGGTAAAGAAA ACTGAATTTATGTGCCTATGTAAGCATAGAAACATACTCTATATATGACCATGTGCATAT TTGCCTTGAAGGATATACACAATTTGAATGAGGGGTAGGGGAGGAGAGGGGGTAGGGGAG GAGAGGAAGTAGTGGTGAAGATGAAAGGAAAAGCTCTCATATTTTTGCTTCATACAAGTT TGTACTATTCAACTTTTTTTAAAGTAGATATTACTTTAGTGACTAAAATAATTTAAGAAT TAAAAGGAAAAATATTTAAAGTAAGCAATACAAATACTCAGAATTTGGTGTTTTCTCTTT TTCTGCCAAGATTATAAACTGATATCACATGAAAATAGTACACTAGAGGTAAATTGTATA CAAAAAATCAGAGTACAAAAATAAAAAATATAGTCTACCTACAGATTCTCTGAGGTCAAG AACACTCTCTAAGAATTAAGTGTATAGTAATCAGTGCATAAATGAATGAGTTTACAATCT GCAGGAGTAATCCACCCACTAAGTGTTTAATAGATCTATTACTAACAGAAGCTTTGAAAA TCACTGGTCCAATTAGTGCCTCCTTTTTCACGTTTATGTATTATGTTCTAAAAATTTTAT TAACTTTGTATCTCACTCAGGGTGAAATCTACATTAAGATGAAAAAGCTGTTTATTTTAT GCTGTAGCCATACCTTTCAAAACTCCTCATCCTTCCCAATATAGAGTCAGGCGGTGAAAC TTTTATGAGGACAGTGCTAACATCACTGATTTTCTCTAGGGGTATAAAAAATACTGTCAA GGCCAAACCATGAATATTTATGCTAAAAAGCAAGAGTTAGATAAATGTAGAATAAGACAG TGAGAGAGGAGCTGTGGTTGGAACAGGCGAGCATGGTAGCTGGAATGAGATATTTTATAT AAGAAAGAGACAGAGTCCAGTGGTCCGTGAGACTAAGACAGAAAGTGGCTATTAGCTTAC ACTGTGCATACAGGAAGAATAGTCCCTGAGGCTTCAGTAAATGCTTCATGAGTTCAGAAA AAATGAGGTAAATGACTACACAAAGGAAGTGAATAGAGACAGATCAGGGCAGAATCAACA CTGTGGTCAGGCAGAACATGTAAACAATGCAAGTAAGGGAGGCCCACCAAAGTCAAAGCT CCAGAAACTGCAATGAAGAATTACAAAACAGGGTAAAGCAGCCAGGGATAACAATACCCA TTCGAAAGCTTGGATAGGTTAGGCACAGAATATTAGCAACTCACATAAAATAATTAAAAT TCAGAGTTTGGAGGTGTCCCTTGGCATGGCAATCCAGACACCAAAAAACTAAATAAAAGT TTCAGAAAGACAAGAAAAAGCAGTGATTAGAGCTGAGACGTTAACAGATTGGATAAAATG TACAAAAGGATGAAATGGCCAATGTTCAGAACCCTGGCAGAATGAGGGCTAACAACAAGA GAAATTTGATAGTAGGCTAAGATTGCTGAAGAAAAGAACATTTTATCCTGATACTTTCCC TATGCAGGAGCAAAGGCCTCTATGGAGAGTCCAGAGACCACAGCTGACCACCAATAGTTA CTCCTAATGGCAGTAGAGATATAAAGGATGGTAGGCAAAGGTCTCACATAGTAAGTAGGA CTCTCAGGTGTTCTTATTTCTTTATGAGATGCATACATCAAATTAATGCAGCATCCTACA TAACATAGAGACATCTATTTTCTGAGTCCAGATATGCAGAAAAAGTCTTATGGGAAAAAA AAAAAAAAAGCCTCACTACTCTAAGATCAAGGGCTGTGAATTTGTTGACTTTCAGTAGCC AATACCTGATTTGATTTTAAATAATTTTAAATGCCCTGAGCTGTACATTTTAACTATTTT TATACACCAAACAGTAATGCTTTTTCAACACCATTGCTAAGCTTGAGTTTGAATTTCAAA CACCTTTGATTTATAATTCCTATATACTGGGAACTATATTTATTTCAATCTCAATTGAAA ATAATTAAATCCTTAAAATTTTTTGAAACTCTTTAAATTATAGAATACCAACCCAAATAT AAAGTTTTTTAAGTTAAGTTTTGGAAAAGTGAAATTTGTATCATCTAAAATGGGTCCAAT CTTTTTTTCCTACTGCAACAATATGTTCTAGTATAAAGGGCAAACGGTATGCATATCATT AAAAACAAACAAACAAACAAAAGTAAATCATTTCATCTGTTGCCCACCTACCCTTAGCTT CACACCAACCCCTGTACTGCATATATAATGAGAATCTTTGCCTCAGTTGAGAATCACTGA CACACAGGCTAGGTAAGTAAATTCAACCTGCAAAAAGAACTTGAAAATTAAGTCACATAA TACTGAAACATTGGTTATTGGACAACACACCTTTCATAAAGGAAGCCAAGGCCATCTTAT TCATTATCCTTTGTGTTATGTTACTGACTGGTGTATATGCCACTACCAGGCCAGAGTCAT TAAACTGATCCACGCTTCCCAGGACTTTAGGAGGTTGTTCAGGAAAACGGGTAGCTCTGA AGTGTTCCGAAAAGATGCACAAATATAGCCCTAGAAACAATGTTATTGTCCATTCCTCCA GCACACAAAAGAGAAATGAGCCATGTTATAACGTGGTCCAGACCAGTGAGAAACATCCAA ACACATTTTTAAGGCAGAATGTATTGCCATTGAGCATGACTTCATTTCAGTCTGTAATTT TTTTCTGCCCAAATTAATATCTACCTTTTAAAGAAAAAAACACCCTTTCAAAAATACACA ACTTTTGAGATAATATCAACAATTGCAATCAATCTTAACCCAGTGATTTAGCACCCCTAT TAGTGGGACTGCCATTGATTTTATGCCCTCATATTTGAAGCAACGTAAGTATATGGCATC ACACAGAAGATACTCTTGCCAAAAATATTTAACCAGAATTGGATCCTGCTTTTAGATCCA GCTCACTGCTTACAAAAAATATAGATGATAAAGGGATGACTTAAATGACAGCATGGAGAG GCAATCAGATAAAAAGAGAACATGGAATATTCAACAGGATAACTAGTTTTGTCTCATTGG TTCCTGAACAAATCAACCTTAAAAGACATTTTGGGGGAAATTTGGAAAATTGAATTTGGC CATGGAACTAGATGATATGGAATTATTTTTAATTTTGTGTAGTGGGATAGTGGTAATGTA GGGAACCAAGTTCTTAATTTTTTGAGATACTAAAATATTTAGCCATTACATATATTTTAG GGAAGAAGAGGAGACAGAGAGATGAAGCAAAGATGGCAAGATGTTAACAGCTGTCAAATC TGGATGGTGGATGTATAGGTGTTCATTGTACCAATATTTTCACATTTCTGGATTGACATA CTTTTTTTAAATTCTAGTGAGTAATAAATATAGATGTATCCTTCTTCAATATACGAAGCA AAATATTTGATCGAACTGCTTCGGAAGCTATTGCAGAAATTTAAAAGGATGATATAAATC CTGTTAGCTCCCACTGAAATGGTACTGACTATTTCTGAACAGACTGCAATCTCTACATGG TCAAGGCAGATCCAGTTATATCTCATAGTAACACAAAGCAATGTCTTAATATTCATGTCA GCATACAAGAAACTCAACAGAATGCAAAGGTATTGACAATCTGTGATCTTATTCCATGAA ACCATTCTATGTTTACAAAAAGCACGGCTTTGAAGAGATTCCAAAAAAGTTTGCAGATTT TTACTCATAGATATTTTCCCAGCCTTACCAAATAACATGACATTAATCGAAATGTCCCCA AATAGTATCAGGGTTTGCCCACGTAAAAATCTATTTTATTTTGCCTAGCTTATCTTTCCC CTGGCTGTCCCTGCCCCCAACACAGAAGTTAGCTAAGAGTAAATCAGAATGACTCTGAGA TTTGAATGCATTAATTATGTGGAAAATGGCTGGTTCTATTCTGCAAAAGATTATTTTTCA GGAGCTGTCAGATGAGCTTTTTAGTTAATTTCACATTTGACACAAATATTATCCTATTTT GCAAAATATATATCGTTTTGCAGTATTTAGAATCTCAAATCAACTAGCCAGTATGATAAT TAAAAATCAGAATTTATAAACAAGAAAAGTAATAAAAATGGCATAATACTATATGGTGGA TTTTCATTTATTAATTATGGATATATATATATATATATAGTGAATCATACCAATAAACTC TCTTTTTATTCTCCATTTTTTAAGAAAATTCTTGTACAGAAGAGCCTGAATTTGTTGACG CACGCTTATCTCTTTTTTAACCATTTTGTCCTGTTCATTAACAGGGTAAAGTAAATATTG CAGAGCAATAGCTAGGGGAAAAAAGAAAAAAAAAAAGTTCAGTTACAGAAAGCCTTTGAA CATTTTGAAAGCATAATTTTCAGATGTGCCAACTAAATGCCTTATATGACACTGTAGCAA CATATTCAATCAGGATTTTAAAAAAGAATATAAAGTATTAGTAATTATAAAATGTCTTCT CAGTTGTTATTTCTCTCCAGGCTTTTATGGCTATGAGGGAGATAAAGGAGATAGTATATA AGACCTTTCTCCTTTTGTCTCAGAAGTCACTTTTTTTCCATGAAATCTTAACATTACATC CACCTAAAGTAAATCCCTCAATAAGATCTTAGTAATTTTTAGAATCCAAAAAACACTTTC TCTTTACTTGTTAAGAAAAAGAAGTTTAACAGGAAGAAACCACTTTGCAGTTCCTTGTCA GTCAGCAATTTGACCACAAGCTGTCTTATTTTGAATTGCACATCTGGGCACATGTATTTG ATATCTTGTTAACCACTGGGCAAAGCAAAGTCGAAAACATTACGGCCATTCTTAGAATCC CAAAAAGCTAATTCCTCTTTTTTAAATCTCCATTTATGAAGTAAATATGTAAGATACATA CAGATTAAAACCAAAAATATTGGCTAATATGACTAGAGTAATTGATTTGTAATAATGATC CTTATTCTTTGTTTTCAATTTGAAAATCCAGAGCTGATCATTTGGTGTCACAACTATGAC TACTGAAGTCCATTTGAATAAATGTTGATATTATATACAAATTACAATGTTCAGAGAGAA CTTGCTATATTTCCCCTTTTTCATAAAATAAAAGGCAAAGCCAGCAAAACCCAATATAAT CTCTAAATTCTAACTTAAGAAAGTAGAAACATTAAAACACCAATCTTCACTTTATGGATA CAGAGGTCTACTTAAACAGCTCCATAAGCAAACCACAAAAACATTTTAAAAGAACAAAAG AACACAGAAAAAAGGAACTTGCCCTAATGCTCACACATTCTAAAGAAGTAAAACCATACA AATTCTCAAAAGGATATTCAAAGCAGTGTCAGAGAGAGAATTTATTGTCTGATAATATTT ATATACACCTCTGAATCTAGCCATCTTTCATTTATCACACTAAAATGTTACATAAGTTTT TAAAATAAAATAACTCACTAGTACTATAACATAAAGCATAAAATAATTTAGAGCATCTGA ATAATATAATTTTAAAAATTTCAATCAATATGTTTGGCTTTGGCTATATACTTTATATCT TTAAAACCTTATGCAAAGTGAAAATGTAAAACAAATTTTAACTTACAGTTAAGAAAATAA GAGAGAAGTATTTGAAGCACTTGGATCCACTGGTCTCTTTTTGTCCAAGAAAACAATGAA GAATCCTTCAAGGACTCCTCTACAAATGGTTGCCTCTTTTAAAACTGTTTTGATTCAGCT TGGCTTCTGAAAAGCCATGGTCTGTGTGTAGAACATGCCAACAAATTCTGTTGGTTTTTT CCCTATGTTTTTCTCCTTGTCCAGTTACTCTTCAGAGAGTGTAATGAATTGTTGGCTGAG CGCATCATTGGTATTTGTTTATTGCTCTTTTTGGCATACACACAAAAAAAGAGATCAAAT TCAAAAAGAAAAACCCACATATTTACAATTGCATGGATAACTACATATTTACAATTGCAT GACTTTTAATAATTAAAAATTTGACAGCCAAGCTAAAAAAGGAGCAAATTAAAGATAAAG TTGAACAGAGAGAGAGAAAATGAGGATTGCTCATCTCAGAAATCTGAATCATTCCAATGA GAAAGTTTCATCTGAAAGTTAACTGCATTTCAGTTAAATGGTTCCTTGTATTCACTAATT CCTATGTACTAGAAAGTGTTCTAAGGGTTTAAATGAATTCTCCCATTTGATACTCAAAGC AAACCTACAAAGTTGGTACTCTACTCACATCCATTAAACAAATTTGAAAGGTGGGGCTAA CAGGTGAAGTTATTTGCAGATGTTTAAATAAGTGTGAAGCCAACAGATGAGTCCAGAATA GTATCTGGACTCCAAGATCCCTCACTCTTAACTACCACTATGAAAATGGTGCTAATCAAG ACAATGATATCTGATACCCATTTAAAAAGTGTAGTGGTATAGACTAGATGGCATAACTTT AATGATTTTGTTACTTTTTTTTCAGCTACAACTAAATTGGATATTCTCAGAATGGCAAAT AATGCCTCTTTATCAACCCTGAAAATCTTTTTATGTGATTTTAACTATAATAATACACTT CTTGGTATGCATACAGAAGCTAATGCCCATTCATGAAAGTGACAGAGACAGAAAGGGTAA AGGACTCAGAGACTCTTCAAATGATTACCATTTTCATTAGGAATATGGAAATAAATGGTT CCTTTAATTGTAAATGTCACTAACAACAAAGGAAGCATACTTTAATTGCTTTCCTTTGTT GTTAGTGACATTTCTCTTCCTATTCAGGCAAAATCATTACTAGAAGTAAAAGTTCATGAA ATAGAAAACATGAAACTTAACCTGGTTCCGATCCCAGACATTAATGGTAATATTCACTTA AATGGGTGGGGAAAACAATTAAAATCATACTATAATACAGACATACACCCTTCTTAATCA CCAAATTTTTAAAATATTTTTTATTTCCATAATTGCTGTGATTTGAATGTCTCCTCTAAA ATTCATGTTAAAATTTAATTACCAATGAAACAGCATTGAGAAGTGTAGCCTTTAGAAGTG GTGATTAGGTCATGAGGGCTCCACCCTCATAAATGGATTAACACTATTATCTTGGGAATG GGCTCCTGATAAAAGGATGAGTTAGGCCCAATTCTCTCTCTCTCTGTCTCATGCACATGC TTCCACCTTTCACCTTTCCACTGTGGGATGACCCTCACCAGATATCAGTGCCATGCTCTT GGACTTCTCGGCTTCCAGAACTGTGAGAAATAAGTTTCTTTTCTTTATAAATTACCCAGT CTGCTGGGTACAACTAAATCTGTGGTGTTCTGTTATAGCAATAAAAAACAAGCTAAGACA ATAATTTTAGGGATTTCAATCTCCAATACGGTACAGTTGGGAGTCTGAGACCTGCATTGC AGACTTGTCACTCATTGTCTGTGTCCCTTGGAGAGGTCATATAAAATCCTCAGGTCTCTG TTACACATTTATAATAGGATTTGGACCCTTTTCATTCTTAGCCTTTACATATTTATAATT ATACAGTTCTGCTACAGAGTCAGAATGTTGAAATACTCCAGATTTAGGCTTATGCACATC CACGTTACATAATACCAACTAGCACCTCCTCATCAAACTCTTCCTTACTCTTGAGTCCTT GACCCCTGAAAGCACGATGGCTTTCAGCAGGTAAATGTACTATATTAATGAACAATCAGA GGCAATTTGGCAGAAGTTTTCCTCCACATACCTCTATTTCATTCTAATTTCCCAGAGGAA ACTCAGCCAATTTTTTCTAAACTCAACACCACTGCAGAATCCTTCGATCAAATTCTATTA CCTAATCTAAAAATCTAGCTCTCTTGGTTATCTCTTTTTATTTTATTGTTAATTTCTATT ACAATCTCTTCTCTCCTTCCATCTTTCTTTACATATGACTGGCAATTACATATGAGAAAA TATTGTCACTGCCAGCTTTCTTAAGCTACCTTATCTTATAAAATATCTTATAAACTAGCT CATCTTCTTACATTCCCTGCCCAAATTTCCATTGTATTAGTTTCCTAGGGCTGCCATAAC AAAGTACCACAAACTGGGTACCTTAGAAATTGATTTGCTCAAAGTGTCAGAGTCCGGAAG TCCAAAAATCATTGTCCTATCTGAAAAGCCATGCTCTCTCTCCCAGCTTCTGGTGATTGC CAGCAACCCTTGTCATTCCTTGACTTGCAGATACGTAACTCTAATATCTGTGTTGTCATT ACGTGGCATTCTCTCTTCTATGTGCCTGTGTCTTCAAATGGCATTCTCCTGTGTATTTGT CTCTTTCATTCTACTAATTTTGAGTTAGTTTGCTCCTGTTATTCTAGTTTCTTGAGTTGC CATGTTAGGTTATTTGAGATCTTTCTACTTTTTTGATGTAGGCAAGTATTGCTATAAACT TCCCTCTTAAAACTGCTTTTGCTGTATCCCTTTGGTTCTAGTATATCATGTTCCCCCTTT TTGACTCAAGAATGTTCTAAATATTTTCCTTTTTAATTGCTCCATTGACCCATTAGTGGC TCATGAGGATGTTGTTTAATGTCCGTGTATTTGTACCATTTCCAATGTTCCTCCTGTTAT TGATTTCTAGTTTTATTCCATTGTGGTCAGAAAAGCTACTTGATGTAATTTTGATTCTTT TAAACTTGATGAGACTTGTTCTGTGGCCTAACATATGACCTTTCCTGGAGAATATTCCAT GTGCTGTTGAGAAGAATGTGTATTCTGCAGCTGTTGGACAGAATGTTTTATAAATGTCTG TTATATCCATCTGGTCTAATATGTGGTTTAATTATAATGTTTCTTTGGGATTTTCTGTCT GGATGATCTGTCTATTCCAGTTCCTTACAATTATTTATTGCAGTATATTTGTCCTTTTAG ATCTATTTATATTTGCTTTATATATTTCGGTACTCTTATGTTGAGTACATATGTATTTAT AATTATTATATCCTGTTGCTGTACTGGCCTCTTTATCATTATATAATGGCTTTATCTCAT TTTAAAGTTTTGGTTATTTTATCAGATATAAGTATAGCTACTCCTACTCTTTTTTTTGTT TCTATGTGCATAAAATATCTTTTTCCATCTCTTCATTTTCAATCTATGTGTCTCTTTACA AGTGTAGTGAGTCTTTTGTAGGCAGCAGATAGTTGGGTCTTGTTTTTTATTCAATCAGCC ACTTTATGTCTTTTGATTGAAGAATGTATTTCATTTATATTCAAGTTAATTATTGATAGA TGAGGGCTTACTGCTGCCATTTTGATACCTGTTTTCTAGTTGTTTTGTGGACCCTTTCTT CTCTTACAATCTTCCTTTGTGTGTAAATGATTTTCTCTAGTAGTGTTTTGATTTCTTGCT TTGTATTTTTAATATATCTATTATAGGTTTTTGCTTTGTGGTTACCGTAAGGCTGACAAA AAAACATCTAACAAGTTATTTTAAAATAACTTAACTTTGATAGCAAAGGAAAAATAAAAA AACTGTACACTTAATTCCATTCTCCTCCCACATTTTGAATTTTTGATGTCACAATTTTTA AATTTTACATTTTATATTGCCTATCTCTTAGCAAATAATTTATTATTTTTAATAGTTTTG ACTTTTATTCTTCATACTAACGATATAAGTGGTTTATGCTCCACAATTACAGTATTAGAA TAACAATCATGTTAGCATTCTTCTCTTTAGATTAGAACTCCCTTCAGCATTTCTTATAGG ACAGGTCTGATAGTAATGAATTCCCCTCAGCTTTTGTGTGTCTAGTAAAGTCTTTATCTC TCCTTCATTTCTGAAGGACAGCTTTGCTGGATACAGTATTCATGGTTGGCAGTTTTATTT TCCTTCAGTACTCTGAATACATCATGTTCCACTCCATCCTGGCCTGTAAGGTTTCTGCTG GAAAAGTCTCTTGTCAGGTGTATTGGAGTTTCCTTATATGCTATTTGCTTCTTTTATTTC TCTATTTTCAGGGTCCTCTATTTGTCTTTGACCTTCCAAAGTTTGATTATAATATATCTT GGGGTATTCTTATTTGGGTTGAATCTGATTGATTAGCTGTGATCTTCCAGTTCCTGTATA TTTATATCTTTCTCCAGGTTTGGAAAGTCCTATTATTATTTCTTTGAATAACCTTCACAC TGCTTTGTCTTTCTCAACTCTCTCTTTAACTCCAACAACTGGAATATTTTCTCTTTTAAT GTTGTTCCATCAATTCCATAAGCCTTCTTCACTGTCTTTTCATTCTTTTTTTTACCTCCT CTGATTATTTCCAAACAGCCTGTCTTTGAGTTCCCTAATGTTTTTATTCTATTTGATCAG TTCTGCTCTTGATGGTCTCTATTTCATTTTTCATTATGCTCCCTGTATTTTTCAACTCCG GCATGTTTGTGGTTTTTTTAATTATTATTTCAATCTTCATTAAATTATCTGATAAATTTC TGAATTGTTTTTCTGTATATTCTTGAAGTTCATTGATCTTCCTTAAAACAGCTATTTTAC ATTTTTTGTCTGAAAGATCACAATCCCCATCACTTTAGGGCCAGTCCCTGGTGCCTCATT TTGTCCAGTTGGTAAGGTCATATTTTCCTAAATGTTCTTGATGCTTGTGGATGTGTGACA ATGTCTGCACATTGACGGATTAGGCATTTATTCTAGTTTCCCCAATCTGGCTTTGTTTAT ATCCATTCTTCTTCAGGAGATCTTCCACAGACTCTAAGGAGACTGACTGTTGTCTTCCCT GAGCCCAAGACCAGTACAGCTGTCTCAGCATTAGAGCATTAAAGGGCATGCTAAGCCCAG GTTTGCTATGAGTCTTGGGAGAGCTCTGAGATTTATGCAGCTTTCTAGCCCAGATAGACC TGGGGAAGACCAAAGAAGGGTACCCAGGTTGTATGAAAAATCTGGCCAGAAACCTAAACC CAGAAGACTGTTCTGGTAGCTAAGATGGATGTCCATCTCCTACAGTCCCTGGACAGGTGA GGTAGTTCATTGATTGTAGCAGGTGAGGCCAGGGCTGAGACTGGGGACCCTTGGATCTCC TGCAGAAGGCAGCTGGCAAGCCTATCTTATTGGCTCAGATGAGTGTGCATCTCCCAGCAA GTCTCTGCACAGATGGGCTAGTTCCCTGACTGCAGAGGGGTCAGAACTGAGGCTGGCTTC CCTCAGGATCTATTATGGGACAGAGGCTGGAGAGCACAACATGGAAGTTCAGACTCCCAG GATGCAAGACATGGGCGAGTCTCACTCTAGGTCCTTGTGTGAGCAGTTCTGAGCTGGGAC TTTAGCAGAGAAGGGCTGAAGTCAAGTCACAGGGCAACTTTCAGATTCATTGTCAGCAGT CAGAGGAGGCTCTCTGTTGAGGCACTAGTGTACATGATTCTTTCTGGACTCCTTGGCAGA TGGTTTTGGTTGTAGGCTCAAGACCAAATGAGTTTTTAGCCAAGCTCCTTGGGGAATGGA ACCATTTCCAGGCTTGAACCCAGAAGCAAAATCAGCAGATCAGCCACTAGGGTGCTAGTC TGCACTCTCAAAACAACCTCTAGGTCTTGGGATCCACTGGGGTTTCACAATCTTATACCT GAATCCTGAGGCTCCTGCACAGAGACTTTGGTCTGTGGTGGTGCAGAATTATTGTTGTTA TGGGGGGTGGCGGGTAATGAGTGGGTTACCTTCTATTATGTCATCTTGCTGGCATCACTC TCCCCAGTTAATTTTGATGCTGCTGGTCAATGAATTTTTTGCTCTACAAAATTTGCATAG AGCAATGAAACAATGGCGTTCACAGAGTAAACCTTCAATTAATCTTAATTACCATTTTTA ATGCTTAGTTCTTATACGTCAAGTCTCTTCTAACAATTGGAATTGTTTTACTTCTTAAAT ATTCCAAATAAAATGCCACTTGTTTTTTGCTCATCTTGATGCTTTCTCCCAGTGGGAATT ATCAATTAAATTCTTAAGTAATGATTTGTTTAAGGAAAAAAATTAACTAATTTTTCTGAA GGATGTGACTATCACTGGTTTTCCCTTTTGAAGCAAAAGAAATGAGAAGTAAAAAATTAG ATTTGAGACTATGGTTACATCTTTATTTAAAAAGACGATAAACAACACCATTTCTGGAGG TTTCCTTTAACCATCTCTGCCCATCTCCCTCCAAGTTATCCCAGTTATCAATAAAATTTA CTTTCAATATTAGAGATAACTAGATTCTGTGCCATTTGGAGAGTGCCTGAAACGTTTCCT ATTTTGTGGCTCCTCAAAGAGACCAAAGGAGGGATTTATAACCGGTGATTACAATCTAAC TTCAGGTTCTTGTCCTGTCCTATCTAAGAACCATTCCTGTCCTTTTCAACCTCTAGCTGT TCTGCCTTCTTTAAGTTTGTTGAATGGCTAGGAGTATCCTCTGGCTCACCCCTCTTACTT TGTTCTAACCTCTTGAACTCTATTACTGCCTCACCATTTCTCAAATGAACTAGCACTTGG GTGACTCTGGCTCAGAAGAGTTCTGCTCTGGCTTCTTAGTTCATTCAGTTCTGGCTTCTT AGACTGCCTTGCTGTCACTGCCACTACTCAAGCGGCCTTACCCCACCCCTTTCTGGGACC AGAAAGGTATCCCTTTGGCACAAGCCTCTGCTGCCATCTGGTGGTCAGAGTTTCACTCTT TTTCTGTCCCATTTCTACTAGGCACCCACCCACACCTTGCATTGTGCTGCTTCCACCTGG CAGGATTAGAAACTGTATCTCTCATGGTTACTGAGATTTAAAAAAAAGAAAACAAAAAAA ACAAAAACAAAACCTTAATTTTAAAGTTAGAGATGCAATACTTTTAAATAATCTTGACAC TGTCACATTTCAGTGTAAAATTCATTGTCCCCCAGCACAGTTACAACTCTGAATTTAAAT TGTACATTGTAAATTCTTTTGAGCTTTAACTAGGCAAAAGAAAACTTCCAGTGGCTTTCT ATACAATTCAGTTCTCAACTTTTGTCTCAGTTGTCTGCTGTATAGGTTTTGTATCCTCAG CTGCATGGGAATAACCATGAGGACAAAGATAAGATCCTGGGTTTGCATCTTACAATACCT ATATATATATGGCCAAGTCAAATAGTAGTAGGATTTTTTGAAAAGATTCTTTCTTTGAAC TTCAAAATGTAAGCAAAGCTATTCAAACTTGTGGATCGGCCACACTGTCTTTATAAACAG TTTATTTTTATCCAGGGCACCTACTTCTAATATTTATAATGCAGGCTTGTAAATCCCCCC TGCCCAAAGTGAGTAGTCCCAAATTGGGAACCCCATTGAGAAATGACTTAAGAATAGCAA ATAAGTAACTTCACATGTAAGAAGATAGTTCACATAATATTCAAAGACAACCTAAGATTA ACTGAAAACAGCACTGAAAGAAGACATGCATTCAAATATGCACAAAGACCTTGAGAATAA GTCTGCAGACAGAGTCTATGAAACTGATAGAATGTATTTATTACAAGATTAGAATCGAAA TTTTCTCCCTACTACCTCAATCTGAGTGAACCAGAATCAAGAATCTACCTCCTTTCAGCA CTGAGTATGAAACATTACTTGTGTATGGAAAAACTACAGAAAATAATTAAAACAAACTTT TCCACTGACGCCTTTGGATAAATGAATCAATTTTCAACCCAAATCAATGCATTAAATCAG TATTTTCAAATGGGAGTAATTTTGTCTTCCTCCCCCTACCCCCACCCCAACCCTCCCTCA GGAAATATTTGGCAAAGTGTGGAGACATTTTTGGTCTTGGGAGAGTGTGCTACTGGCATC TGGTGGGAAGAGGCTAAGAATGTTACAAATACCCTGTAACACACAGGACAGTCTCTCACA ACGAAAAATTATCCAGCCCAAAATGTCAATAGTACCAAGGTTAAGATACCCTGTATTAAA CAATAGCAAATCACTTCAGTGCAAAATAAGTTTCCTAAGGAGAAATCCAGTATATTTTGG ATAGTGAAGAGGAAATGGCAAAAGTTATTATTTTCTGGTCAAATATTAATGGCATGGGAT TTTGATATACTCCTTCTGTAGCACAATGTCTAACCAAGGCTTCCAATATACTAGCCACTT CTTACTCATTTAATTCATGATGTCATCAATGGAGTCGACAAGTCTTACGTTCTATGAAAT GACCAGCTGATCCAGGTCTCTTTTGGAATTTATTGGCAGAGAGAAAGAAAACCCTAAACG TAGCCTTAGGGCAGAGCAAAATGTATACTTTTGTACATTCCAGATCAATGCAAAATGTTT CTGATTGGAATGGAAAATGGGCCATTTGCCAAATCAGTGGCTGTATACCACATGACAGAA GCTCTTCTTAATCAGCTCTGGCAAAGATAGCACATCTGGTTAATCTACTCAACTGAAGCC AACAGTTGGCTGAATTTGCTCTAGACTAATATCCTCCTCTAGAACTGGATTTTTGCAGGA CCAAGATTAGTATATTTAACACGGAAATATTATAAAGACCATCCCCCTCCCACTTGCATC TTTAGGTCTTTAAGGGTGGCACTAACTTCTTCCATTCCTTTCCCATTCCCTCTCCCAAAA TGAAATGTTTTTATTTCCTATCTTGACTGCGGCTAGTACAGTTTTCTCACTGTAATTTCC CCAAAATTCATGTCCTTCCTAAAAGCCTCAGTAGGTGACTGTATTTAGAAAAAAGATCTT TGCAGATGTAAAAAGACAAGGTAATATTGGAGTAGGGTGGGCCCTAAATTCAAAATGACT GGCAACCTTTGAAGAAGACACAAGACATTCACAGGGAAGACAGCTATGTGACAAGATTGG AGATAAGCATCTGCAAGCTAAGGAACATGAAGAATTTCCAGCAACTGGCCGGGCACAGTG GCTCACACCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGTGGATTATGAGGTCAGGA GTTTGAGACCAGCCTGGCCAATATGGTGAAACTCTGTCTCTACTAAAAAATACAAAAATT AGATGGGCATGGTGGCAGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAAGAGAA TCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCACGCCATTGCACTCCAGC TTGGGCAACAGAGTGAGACTCTGTCAAAAAAAAAAAAAAAAATTTCCAGCAACTACCAGA AGCTAGAAAAGAGGCATGGAACTGATTCTCCCTCTGAGTATCCAAAAATGAACCAACCCT GCTGACATCTTGATTTTAGACTTTTGGCCTCTAGAACTGTAAGAGAATAAGCTTCTGTTT TTTTAAGCCACTCAATTTGTGGTACTATGTTACAGCAGCCCTAGAAAACTAGTATACACA CTATGATAGTTCTTACCCCATAGGTCAAGAAAACAATGGGGGTTATGCCAACTCCCATGT ATATCTATTCCAATTACAAATCAGGGACTAGAGACATGACAGATAGGTCTACAGACTAGT GGATTCTCTATGAACTAGCTCTAGGCTAGGATTTTAGTTATTATCTAGAACTCAAATGCC TCTTACTCTGTCAGAGAGGGCATGATGATACTTTACTTTGAGTCTTTGGACTTGTGTCAA CTTTGACCCTGTGGTAAACAGGCCTTAAAATGATTGGGCATTCTGTTTTCTCCAGTATAT AATTACCTGAGTTAAAGGCTATAGATTACTTTGGAGGAGGTCTGAGGAAACCAATACCAT ATATCATTTGCAGGGTCCCTCCTCCTAGGGACCCAACTTCTCTTTCAATTGGTTGTGGGT ACAAAAACTGGCTCAGATCCAGAAACCAGAGAGGACTCATGACCTTCTGTTGAGGCAATT GTCTTCAACCTTCTGATCACCCATCATTGATTTAATTGTAAAGAATGAGTACTCCATTGA TGATCCATTCATTTGGCCCCTACAGATGCAATGTTCTATTAAATATCTCCATAACTGTGG ATCACTGTCCCCATCCCCCACAGCCTAGCTGTTGTCAAAGATAACATGGCCTAAAAACTA AAGCAGTGAAAACAAATTTTATTTGGTAACTACTGACAGTAGGGGAAAGAGCTGAGCTGC CTTCTGATCTGTACAGAGGTGATTGGGGTGTTTAAAAAGGAGAGTGGGAGTAGGGAGGTT GTAGGGGCTCAGCAGAGTCAGAGAAATAGAAAAGTACAAAGGGTTGGTCAGTGTGAATGT GATTAGGTCAGCTGTGTTTCTTAGCTGGCAATTATCAGTTAGGATTCTATCCTCTCACAG AGACTGGAAGACAGAGGCCTTATCCTTCTTGATAACTATTTTTAAAAAGAATGGTTCCCA GGTCGTTGGAGAAAGAAACATGTGAGCTGCAAAAGATACATATTTATAATTGTAAGCTCC TTTTAGTAAATAAATGCTCTAAGAAATCAGATCAGGGGCCTGTTATCATGTGTTGGCTAC AACAAAAAGTAGATTTTTCTGGTAGTATTGAGCTTTCTCAGACTGTTATTTAAATGGGGG TAGGGACCTGCGATCACCCTACAGACACTGCCTTATGCTGCTAGAGGCCGTGCTAAAATT TGGTCAAGTCTCTCAGTGTCAGGCTTTCGACAGAGTTGTTCTGTGTTGAGAGCTCTGCAG TTCTTTTTACAGTAATTGTGTCCCCATGGTTTCTTAGGTTTCTAATTGTTGAGTGCTGCC ACCCGGCCTCTATTAGTCAGGATTTTATCACCCCCATTGCTCTCTGTGAGCCCAGTGTTA TCATGGTATCACTTACCATCAGCTCACAGGACAGCCACCTCTAGCTGTATAGTGACGTTG GCGTGCCCTTCAATAGTACCTTCCTTGTTCGTTTGAATTTAGTCATCTACTGTGTTTTCC AAACTCATATAGTACACCCACGCAGGATGCCTGGTTTTCTGGGTGTTTTCACCCTTTTCT TGCATCATGTACCATGGCTTTTCAATATTTATACATGACATTGGGTGGGCAATTGCTTTT TCCATGCAGGAAGCATCTTAACAGTGTGTTCTTGCTAAGAACCATCTCTTGGGATTCTTG CCAGGACATTAAAAATCCTTTAGGCCAGAAGAGTACTCTGAATAAACTCTTATCCAACTT TATGTTCTGCATTGTTTGATCATGCACCCTTAAAATCCAGTCCCATGCACATTCTCCTAG CTCTTATGGGTAGATGTGGCTAGCTCCTGCAGCTCTTGTGTGATACAGTACATTTCTTCC CTCAGAAATACCAGCACAACTTTCGCCAAGTTACTTTATGTCTTAATCCTTGTTATTGGC CATTAGGAAGGAAGTTAGGAGCAGATCCTGGAATGGGGCTTGTATTAGTTTGCTAAGGCT GCCCTAGGGAGTTGAAAAGTGTGACCCGTTTGATGGTAGCACTCTCAGAGGCAGGAGAAA TAAGTTCTTTATTTCTGAAGGGGAATATAGGCAGTTCATTTCAGCATCCACAGGAGCCTG AACAATGGGCCATTCTATGGTCCCAGAATAGAGGAAATGGAGGGTTTGGAGTGGCTAACC TAGTTTCCAAACTAAAGCACTCTTCGGTTGGTACAGTGAAATGCAATTTCTTTAGTAAAT AGTACCATGTGGTGAGATTTTGGTGGTCTGTCTTCTGACTGTGATATTAACTTGTTTCTG TAGAACTCTTCAGCTGCCTGACTTCTCTACATCATCAAGCCTCCAAGGGATGGGCCCCTT CCAAAGTTGTCTTCCTCTTTCCCAGCAGTGCTTTCCCAAGAAATCAATCACAAACTCAAT TTCACTTTACAATTTCCTTCTTTTCAGTTCTTCAGTAGCTAAGATTTGTGCCACTGGGTC TCAAATCTGTTCTCAGAATTTCCTTACTCTGGGTAAGACCCCTTGCCTTCTGGCAGTGTG CTTCAGTTAACATTACCTATGTTTCACTACTGCTAGGGCCTTGCTGTACCATCAATACCC CCTGACTCTCAGCTTGTGAATGGGTTCCAAAACTAACACTGCTCCCAGTATTTATTTCCT TTGCTCACTGGACATCTCCACTTGGATGTCTAATGAGCATCTCAAACTTAACAAATACAA AACTGATCTTTCCCTCAAATCCTCAAACCTAAACTTCCACGGTCTTCTTCATCCACTTGA TGATACTAGTAGAAGATACGTTCAGAGACATAATTGCTGATAATTCTACTCTTCCAGAGG CTCAGACAAAACAAAAAACAAAAAGCCCTTGTGTCATTGACTCCCTTTCTCCCATACTCC ATGTACTATAATCTCCACCTTCTCAATATTCAGAATTAGACCACTTCTTATTCACCTTCC TGATTCAACTCACCATCTCTTGCCTCATCAAATGCAATGGCCTCCTAACAGGTCTCTTGT GCTCTGTCCCCTCATATCTGATTATTTTCAACACAGCAGCTAAACTGTTCCTTTCAAATA TGCCTAATGTTGCCACACCTCTACTCAAAACCCTCCAATGACTTCTGATCTCATTGAATG TCAATAAAATGTCCATAAGGGCCCTTTCGATCCCATCTTCCACTAGTGTCCCCCTTAATC AGTTAGCTAAAGCTTCACTGGTTCTGTTTCTCAAATATGCCACTCACACCTTGCCTCAGG GCCTTTGTACTTGCAGTACCAACTCACCTTCTCAGTGTAGTCTTGCCTACATGAGATCAG TGTGCTTTCATCTGCAGCACCAAGAGTCCTTATCTCCCTCCCCATCATCTAACATACTAT GTATTTTTTTAAAGTAGGTAATTTGTCTTACTATAATAAAAGCTCAGTGAGGGCAGAGAC TTTTGTCTATTGTTTCAATAATGTATATGCCTAGTGCTTAGAAAAGTGCTTGATTCTTAA CTGACATACAATAAAATATTTGTGAATACTGAATAATAATGAAAAGCAGTCTTTCTTTGA AACTTAAAGACTTTAGGCACCATCATAGACGGCTCTAAAAACTATCTAGTGTCTTAATTT GGTGAAGGTAAATTCAAAGGATGCCTACTTACTAAAGAATTAGAAGATACAGATAAGGCC TTTTAAAATTAGCAGATATGATAACACTAGAAGCTGAGATTTCTTACCAATTTGTAAAGC TTGATGTATAATTTTAATCTCATTCTATCACAAACTTGATTTCATGTACACTGATGTATG AGAATTTAAATGTAGTCAACAGAAAACCAATATCAACTACATCATAATCACATAACAATA TCAATAGTATAATTTGGCCAAAGAAATTACTAGCCAATACATATACATCACAACTAGCAC TCAACATCTTTTCCTACAACTATATGACAAAGATATGTTAATAAATAAAAATTAGATAAG GTGAACCAAAACAATAATGGTATTATTCTGTCAGTAAAATGACTATAGTATTATGGTTAA TTAGACATATAAGAATTACAAAACAGAAAGGAAAGTAAAATTGCAACCCAGGTGAGGAAT TCATTTTCTTTCTTTCTGTTTTTTTCTTGAGACAGAGTCTCGCTCTGCCGCCCAGGCTGG AGTGCAGTGGCGCGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATCCTC CTGCCTCAGCCTCCCAACTAACTGGGATTACAGGCACGTGCCACCACACCCAGCTAATTT TATATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGACTGGTCTCGAACTACTGAC CCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGGGCCACTGCACCCGGTCTGAGGAAT TCATTTTCATTAATTAAGCACGTTATACTATAGTCACAACACAGAAGCTGGAAAGTCCTA TTATCATGAATTTGGATGAAACGTAATAATAAAACCTAAAAAACATCTTGTTTTAGCGGA AAATACTGGGTTGCAAAAACCTGAAACTTAGATTGGGTTAACTCACAACTTAAAGCTCAA AAATCAAAGTTTGAACATAAAAGAAGGGCCACCTCAACAGTTGCCAGTTTAGTCTTAGAA GGCAGATCCAGGTTCTATGCTTATATCATTATTTAGTTTAGTTGATAGATACCCCTTGAT CAGTCCCAATTGTTAACTGAGAAACCTAATTAGCATCCATCTCTTGGTCTCAAATTATCA AAGGGATAAATTTTGATAGTGTGAGATAGCTCTTTTATTGGCAAATGTGTAACTCTGCAA AGGTATATATGTAGACACGGTGAAAAAATTACTTCTGATTAGTGTACTGATACTGTATTT ATTTGAGAATCTTGCACACACATCACGTAACAACAGGGATATGTTCTGGGAAATGCATCA TTAGGCAATTTTGTCACTGTGCTAAGGCAATAGCCTATTACACATCTAGGCTATATGATA CAGCCTGTTGGTCCTAGGCTACAAACCTGGACAGCATGCTACTATACTTAATACTGTAGG CAACTGTAACACAATAGTAAATATTTGTGTACATAGAAAAGGTACAAGAAAAATACAGTA TTATATTTTATCATCTTACTATGTGGCCCATTTTTGACCAAAATGTTGTTATGCAACACA TTACTATATTTATGCAAGTGTGGCTGCAAGCCTTATAACCAGGAAGTTTTGTGTATTTTG CCTATTTTTACGATGCTTGAAGGCCAGGTACAGTGGTTCACACCTGTAATTCCGACACTT TGGGAGGCCAAGGCAGGAGGATCCCTTAAGCCCAGGAGTTTGAGACCAGCCTGGGCAACA TGGCAAAACCCCATCTCTACAAAAAATACGAAAATTAGCTGAGTGCAGTGGTGCATGCCT GTAGTACCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACCTGAGCCTGGGAGCTTGAGG CTGCAGTGAGCCGGGATTGTGCCACTGTACTCCAGCCTAGGCAGCAAAGTGAGACCCTAT CTCAAAAACGAAAGAAACACCAAATGATGCTTGAAATTCTTGAGAACTTGATTTTTTAAT TTAAAACGGTAATTTAATTTGCAAGAGTTGTTTAGGCACTTGGGAAGAATCTGTTCATTA AGTTTAAAATATTGCCTAAGTGTTTGTATGAATCAATTCATTCAAAAATTCTAAGGAAAG TGATAAATATGTAAGTAGTGTTAAATATCTGAGAGTAACTGAACCTGTTATATGTGATAA TGTGTAAGTTAAAGTGATTGCTTTCTATTTACAAAAAAATACATTCAAGACAAAAAGATC TATAAACATACCTAGTTTATGTTTAAAATCTGAATGTAAATTAAAACAAAGTAATTGTCA ATGTTCCTTCTGCACTTGAAAACTAGCCTCAGATACTTAAAAAAAATTACTAACAATTTT AGTGCCAGGTTTTTGCATCATTTTTAATATGAGCTACTCATTATTCAATTATCAGCACTA AATAACAAAGAATTCACTTCAGTATACAAAATGACTTGTCTTAAATTTTCAACTCTTAAA GCTTATTATTAATATAATCATATTTATTTTTCTTAAAGAGCAGCATTGAGAATTGCTTAC ATATATTATAAATAAAAAATAATTAAACTTTTACCTGATAAGAATAGCTGATATAAAAAT TATTCATCTGAGAATAAATTCTTTCATTTTAGGAAATAAGCTATTTCAGGAAAGAAAATA AAAAATCAATGTTAGCAAATTAAAAATACATTAAGGATAAACATTTCTATTTCTCAAAAA TTAATGCCTATTTACATGTTACACAAAAATACAGTATGGTATTTTAACAAACTCAGGGCA CAATTAGAATGAAGTTTTGAGTAACTAACAGAACAACAATAAAAACAATAATAACAACAC TTATCCTAAGTAAAATTAATTGTGCTCCTATAAAACGTTGTTAGTACTACTAGCAAAGGA TTTGTCATATTATAGTTAGTTATATAAAATAATAGCTAGTTATATAAGTTATATAAGTAA TATATTATATATATTTTATGTAAGTTATATAAGTATCTATCTTACAGATCTCCACGATCT TACAGGGCCAAAACTGATAGTCATCCGAGTTCTCTCCAAAGAATCCATTTCTGGAAACAT AATCACTTAAAATATTTGTTAAATTACATTACTCTAAAAATGTTTTAATGATTAAAACCA AAATACTGACCTAAGATAATTTGTGCAAATTTAAAAGAAAAAAATTATTTTAAAGAAAAC CCACTGTCTTTACTGAAAACAAACTAGAAAAAAAAATTAAGAGCCCACAAAAGTAAGATG TAAAGTACACTCATCATGTTTTTTCTTGCCTTATTAGTCAGTAAACACTCACTCAGTAAA GCTCAGCTTTTACTTTCCTTTGAAAATTTGACCATGAATGGGAAATATAAGGTTGGTGAT GTTGCTTTTGCCTAATATGTATATTTATTTATTTATCTGTACTGACATAGAAAAAAGTTT TGAGATCAGTAATTTAAGACATTTTAAAATTAGTATGTTCATAAACATGAACTGTACACT GTAAATAAATATATTTCACTTTTTGCCTCCTTTGCTTTCCAGCTCACTTACCCTTGTTTT CCTAAGAATTAAGTTATATTTCTCCTGAGTCAGATTTTGTTACTGTGAAAAAGGGAACAT AATTTAATTTAACAACCAAAATATATTCTGAGTATATAAAAACTAAAAAAAAATTTGAAT GTCTTTTAAAATTGTTTACAAGAGCATGTATTCATATACATTAAAAGCAAAGTAACTAAA TGAACAAAATAAATAACATGATTGTGACTACTCAACTTTCACTTTGCAGGAAAAAAAATT TACTTTGCACCAATTACACATTCACAAATGTAAAGTGAAAGTTACCAAATCTACGTGCAA AAGCAGGTAATTTTCTTCATTAGTCATGCTCTATCTTCAGATGACATAACTTTCTTAGGA TGGTCAGGTTCTAAAAAAAACTATGCTTTTTCGTGACTGCCTTAGTAAACTATAGATATA ATTTTGTTGCTTTTACTAAACTTAAGTATTCAAGGTTACACATAATTACAAAAGCACATC CCAAAAAAGAGGTCCCTGGGTATTTATGTGAACATTATATATACTTTAGGAAAGTGTATA GCAACTGCCCCCAGCAATGGGGGAAAATATCAGCCACGTACTTTGTACCGAGAAAGAACA CTTTTAAATCCACTGCTAGAGCCTAAAATCACAGATGTCTTATTACACAATAAAGCTAAA AGTTCATTAAATTTTGCCTACATTAAAGAATGAATAATGCCACTGAAAGGTTTTGCTTAT TTAAAGTAATTCAGTACCAAATCCTTCTGTCATTGCTGTTGTTGTTGTCTAATACAATAA TCACACTCTCAATATATTTGTTTTATGAAGTTAATACTTTCATTTGGTTGAAATGTAATG TCAACTAGCATTATTTACACTATTTTATACCTTGAGCCAATACATGGGTTGTACAAGGAA GTATTTCTAAGAAAATATTAGCCATGCCTTTAACTCTATCAAAAATGAAATTCTGGTTCT TATTAAAAAGAAATAGGCGCACTGCACTTACAATTCTTAATTTAACCCTTGAAAGAGTTT ATTCATATCCTACCATGTTCCAAAGTCAATGAGGTAAGTTACTAAATAAATCTACACACT GATCTACTTACAATTTTATAGAAGAGATTCACTAAAGTTTACCAATAAAAACAAATACCC AATAAAATATTTTATTCAAGAACAAAATTAAATGTGCCCTTTGCAAGGAAGATGACAAAA AATTTATATGTTCCAAGAGTGATGAAGGAAAAGGTATGGCTTAATTCTACCACCTCCATA GATAACTGTCATTCTAGCCACAGAGTCAAAGAATCAGACTATTACGTAAGATTCTACACA CAGTCTTCCTTTAATTATAATAACTAAAACCTTCTGAATTTTACTTTAAATTAAAGAAAT GTAATTTCACATACCTAATTACCTAAGCCTAAAATCATGTACTAGAACAAGGGCTCATTT CACTTATTATGATCAATGACTGCCACCTAGTGGATATAACTTTCCTCAAATCTCTATATT GAGATTTCCTAGTGCTTACACTTCAGCTTTTACGGATGACAACTTCCATTCAAAGTGGCT TTTTTAGAAATTAAAAAGGAGAAGCAAGAAACTTTCACATTGCTTTATGTATCTTTTCTA TGCATTAGTTATGAATTAGTTTTTTATTTAGATTGGAACATTACGTACTTATTTAAGAAG ATGGCATAAACTTAAAGATAACTTAAAAATAAAACTATTCTATTACAATTCCTTTAAATC ACAAATTCAGAAGCACTGTTTCTGAATGGTGAAAAAGATGACATACAAACTATATAGTTC AATATACTTCAATACAAACATGCAGCTTCACTTAATTATACATACGTTTTATTTAAAGAA AAGCAAAACACACAACCACAGCATTTCAATTAAGGAGCTTAGAAAAATTTCAAGTGCGTT CTTGGTTCTCCAGTTACCATTCCAATAAAAAACTTTTTAAACCAAAGTTAAAATTAAGTG AAAAAGAAAGAAGTCCCAGTAAGCAGACCGAACAATACAAATTCAAAATACTACTCTATC TTCTTGTGTTCGTTCCCACCAAAGTGTGCTGTTTAAAGTTCCACAACTATTATCTTCCTC CTCTTGTTCTTTAGTGAGTTCTACAAAAACCTAGGTGAAAAGAAATAAATGAATACAGTA TGCTGTATCTCAAGTACCTCAAAGAACTTTTAACTAAATCAGAAATGGTACAAGGCTATA TCTAGTTATATCAACAAGTATCAAGAGATTTATTAACATTAACATTATTCAAACAGATTA TTTTCAAAAGTTACATGCAAAGATGAATACTATTTTAGATTAATAGATATGTTTTTTAAA AAATAATTCATAACTACTTAAACAATGTAATTTCAAATACACTAATGTGAAACACCACCA TCATGACTCACTTTCTTTACAAAATGAAAAAAACAGATATTCAAAATCAGCAAATGAAAG TTAGCTTGATTTAAGCATTCCATATTGCACACATGTATCAAAACATCACTGTACCCAATA AACAGTGTGATTTGTCAATTTAAAATAATATCAATTTAAAAAATAAAATTTAAAAAATTA GTAAGTGAAGAACCTAAGGTTGATTAAAATTATACCAAGTTTAAGATCATTCTGTACCAA TTTGTCACTGGTTTACGATATCTCTCCCTCTCTAATATAAACCAAAACAATCGATATCAG ATACTTTCTTCTATAAAATAATTTTTAAAAATTTAACTTTATAGTACCTGTTCCAATGTT GCTTGAGAAAAGCTATATTCTTCAATGGCAAAAGCATGTTTAGCTATTAAAATATAAAAA TAGTATTTTACTTATCAATATCTGAAAAAAATGGCAATACCTACCAAAGTGGCTAACAAT GTTTTAAAATATCTCTGTAATCAACCCACTTAAATTTGAAGCTGCCAAAACATGTTATTT TTCCCGCTTACTTCCTTTCTCTTCCCCACACCTATAATTCCTCTATAGCCCTAAGTACTG TATGTTGAATGTTACTTGTCTTATTTCACTTTTTCTAAGTTCTCCTCCATTATCTTTTTC CTGGTGATTCTTTTCATGTCTTCTTTTGATCCCTGCTCTCTTATCTCCCATTCTCCAACT CCACTGTAGCCTATTCTGGCTTCTTGAACTAGATTCTGGATATTGGTCCTATCTCCATAA ACCTTTTGTTTTGTTTTGTTTTGTTTTTAAGACAAGGTCTTGCTCTGTTGCCCAGGCTGG TATACAGTGGCCTGGGCAACACAGCAAGTATACAATCATGGTTCACTGCAGCCTCGACCT CCCAGGCTCAAACAATCTTCCCACCTCAGCCTCCTGAGTTAGCTGGGACTACAGGCACAT GCCACTATACCCGGGTAATTTTAAAAAATATTTTGTAAAAACAGAGTCTCACTATGTTGC TCAGGCTGGTCTTGAACCATGGGCTTAAGGGATCCTCCCGCCTCAGCCTCCCAAAGTGCT GAGATTATAGGTGTGAACCACCATGCCGGCCAATAAACATGAATAAACAATGAACATCAT GCAGGCCATATATTACAGACCAAAAAATAATTAATTAGTGTTCTTGGCAAAAGTAAACCC ATTAATCCATAGCTGCAACAAGAATATATACAGTATCAGGAAATCTTTTTGTATTCAGTA ATCACATAAAGAACAATCATAAAAATCCTGTAGTTATTTTGAAAATTATTAATAATAAAC CTTATACATAAATATAGGTTGTTTCACAGTTTATAAATGCCATAAAATAATCTGCATATG AATACCTGATTCTTCCAGGAGGTGATCTCCCTCAACTGTCACCAGCATATATATATTTAT CCTACATACCACTTATTTTTTAAATGCCAAGATTCTATAAGCTTCCTTAAAATTTTGGGG ACTGCCCACCCCTCGCTACACTCAGAATTCTCTTTGCCACTGGAGTCTTGATAGTGTTGC TACTTCTATGGACCAGTATGAAGTAAGGATTCAAGAAACTCAGAGCTCTTGCTGCTGGAC TAACTGCAAAGACTCGATAATTAAGCTGACCCTTCTCATAGATGCAATGTGATAAACTGT GTCAATGCTCTCTAAAAATTGTAAAAGGTTTACATTACAATAGAGTTTATCTACAAAATC CCTATGACATTAGTGTTTACCTGTGTCTTAGATTAAATGAATAAAAGGTTATCTTCTTAT CTGCCATAGTTTCTAAAATAAACCGAGTCCCCAGTTTTAAACTTTTTAAATAAAATTCTT TCATAATTTGAGAGCTACAACATAAGTGCTTTTCAACTACTTACCTTCTTCCAGCTTAAA AAAAGATTGTGAAAGGGACTGAACATCTTCCTTAGGAATTTTATAAGCCAAAATAGAAGA TACTACTTACCTTCTTCCAGCTTAAAAAAAGATTGTGAAAGGGACTGAACATCTTCCTTA GGAATTTTATAAGCCAAAATAGAAGAAAAACTGGAAAAAAAGATAAAATATGGAAAAAAA TTAAAAATTACTACTATTATGTTCTAAAGCTAAAGTTCAACATGTTTAAAATTCAAAATT AAATTCAATAACTTATTTTGGTATTTAGTTGGATGAAAATTGTTTAAAATAATAACATTT TCATGCAAAACAACTCTCATTACTACTAAGAATGTTAAAAAAATTTAAATACTACTGAAT ATTGAAAAATCTAATACTAAGGCAGATATAAAACACCAGCCATCAGACTTCATTAGTCCA GTATTGGTGATAATACAGAGAGAGATATATAAATTATCTATCTACAGATACATATATTTC ATATATATGAAAAAATATACATATATATTCACACACAGAGATATATATATATATGGTCTA TGAATGAAAAGATGATTTTTCACTTAATCCTTAATATAATAACTTTTTATAACCTTTGCT CTATAAAGAAATATAACCACATTCTTTAAAATTTTACCTTTCCTGACGGCTTGCATTTGG GAAAATATACTGAATTTCTCTTTGAAGGCGGTCTACTTCTAGGTTTTCTATCCAGTCCTT CAATTTAATTTCCAAAAAGTAGCCTTTTCCAAATTTACTCTTTAGATGTTGTACTGTTCC GATACATCTGAAGTAATTTTTTAAAAGAAAGCTCAGATATAAAATGACAGCTTCAAAGAA TAATCTCTCACACATATAACTACATTTTAAAAAAATATACCTTTATATTTAGAGAAAAAT TACAAAGAAAATACAGCATCCCCATACACTCTTTATCCGGTTTCAGTTTCCCTAATCTTA TCATCTTATATTACCATGGTAAATTCCTCACAACTGAGACACCGACATTGGTACATTCCT TGTCACTGAACTCCATACTTTATTTAGATTTCACCAATTTTCTATTAGTGTCCTTTGTTT ATTCCAGGTTCTATCCAGGATACCGTAGTGTTCTTGGCTGTCACGTCACCTTAGTCTCTA ACTGTGGGTGACAGTTTCTTACTCTTTCTGTCTTTTTCATGATTTTGACAGTTTTGAGAA GTACTGGTCAGGTGTGTGTTAGAAGGTCCCTCAATTTGGGTTAGTCTGATATTTTTCTCA TGACTACACTTGGGTTATGGGTTTTGGAGAGAATATTACACAGCTGTAGTACTTTTTCCA TCATATCATATCAGTGAATACATGATATCTGCACAACATCGTTTAGTTAAGGTAGTATTT GCCAGCTTTCTCAACTGTAAAGTTACTATTTTTCTCCTTCTGTCGTTCATTTTTTACAAG AAACTGGCTAAGTCCCGTCCAAACTTGGGGGATAGGAGATTAAGCCTCCTCCCTTGAAGT GGGTATTATCTACATATATTATTATTTGGAATTGTTCTGTAAGGAAGATGTACCTCTTCT CTGACACATTTCTTTACTCAATTATTTATTTATGTAAGTAGAAACTCATATGTTTATTTC ATATTTGTGTTACATAATTAATCCAATATATAACAATTTTTTGAAATAACAAGTACTATG CCTAAAAATAATATTCCAAGTTATTGAAATATTAAGTGAATTCAAATTCAAAGTAGACAG CCATATTTTTAAAAAACTCAACATACTTCCAAGTCAATCTATCAAAAGCTAACTCAAAAA CTAAAATATTTAACATTTAAATTACTAACTATTGCCATGTTTTTGAAATGATGACTTTCA AAATCCAACCCCCAACCTCTTCCCCTGAATGGCACGCTATTTAGACATCAACCTTAACTG CCCAGACACCATGATAGCTACTCGATCACAGACAGCCTCTGCCTCCTCCATATAGTGAGT GGTCAGAATAGCAGCCCGCTTTCTGTTTTTAAATGCAGTTCGAATTGCTCGCCTATAAAA CATAAATAAAACAAAAAGAGAGGAACACATCTGTTTGTTAAAAAAAAATGGGTTTTTAAA AATCCAACCGGTTGGTTAATTAAGTTAATTAAAACTTACCAAATATCAATTGCTATGGCT ATTACATCCTGCCCAACTATGATTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCCCCC AGGCTGGAGAGAAGTGGCCCGATCTCGGCTCACTGCAAGCTCCACCTCCCAGGTTCACAC CATTCTCCTACCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGCCTGCCACCACACCCGG CTAATTTTTTTTTGTATTTTTAATAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCT CGATCTCCTGACCTCGTGGTCTGCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGT GAGCCACTGCGCCAGGCCATGACTTTTATATTCTAATTTATTTTCCCTTCATTTTGAAAG CTTGTCAAATGGAAAAAAAAAATCTATGATTTCAAATGTTAATATGGGCTAAAAGTATGA CAACAAATAAATTTTAAAATTGATGCCTTTTCATGTTATAACCAAAACAGGCTTTGAATC ATAAGAAAACCGTAACATGCATCCAAACCAAACCTTACATTTTATAGACATGGAAGTTGA GGCTTAAAGAGTTGTTCAAGGCCAGGCACTGTGCCTCACACCTGTAATCCCAGCAGTTTG GGAGGCCGAAGGGGGCGGATCACCTGAGGTCTGGAGTTCGGGACCAGCCTGGCCAACATG GTGAAACCCTGTCTCTACCAAAAATACAAAAAATTAGCCGGGCTTGGTGGCTCTTGCCTG TAGTCCCAGGTACTTGGAAGGCTGAGGCAGGAGAATCGCTTCAGCCTGGGAAGCAGAGGT TGCAGTAAGCCAAGACGGCACCACTGCACTCCAGCTTGGTCAACAGAACAAGACTCTGAC TCAAAAAAAAAAAAAAAAAAAGAGTTGTTCAACTAATTAGTACTTTACAGGCACTGCATA ATGACATTTCAGTCAATGATGAAACACATTTCCAACAGTGATTCCATAAGATTATAATAC TTTTATAATGTATCTTTTCTGTGTTTAGATACATCTAGATACACAAATACCATTGTGTTA CAACTGCCTACAGTATTCAGTGCAGTGACATGCTCTACAGATTTATAGCCTAGGAGTAAT AGGCTATACCATATAGTCTAGGTGTGTAGTAGGCTATAACCACCCAGAGATTTATATAAG TACACTCTATTATGTTTGCACAACGACAACATCACCTTTCTCAGAATGTATCTCTGTCAT TAGGCAATGCATGACTGTCCTAGAAAGAGTCTCAACATAAATTTAAGACACTATTATTAT GGAAAAGATCATTTGTATGCTAAATGACTAGAAAAAAACTTAAAAACTATTCAGAACACT AGAACTCTTTATCTTAATAATGACTCATGCTTATTTCTGTTTCGGAATATGTAAAATATT ATGAACACTTCATGAAAAATATGCAAAGTTTTAAAAGCTTAAGGAAATCTCTAAATCTAT TTAATTTTTAATTACTAGTGTATCGTTTGAATAGGATTTAAAATCAAGATGTACATATAA CTAACATTAAACTATTATAATAAAAGAAACTGTTCTATTCTAAAGTATCATGTACTGTGT CACAAGTACCATACTCACCACATGTGCTGTTTGGCTTTGGGATCCATACCTGTAGATGGT TCATCTAGCAAAGTAATCTGAGGATTCCCTAGCATACTTAGAGCAAAACACAACTACATG GAAAGAAAAAGATGGGTGGGAAATTAACAAAGGTTCACTATAAGGAATCTATCAAGACAA TATCAGGTACTAAACTATCAATAAAAATACAGGCATTATTTGGTGTTTAATGAAAGTACC TTTCGTTTGATTCCTGCAGGTAGTTTCTTTACAGTCTTCTGAAGATGTTCTTTTAAATCA AGTGCATGTGTTATTCTGCAAAATGAACAATACAAAATGAGAATACCATGATATATATAA ACACAAATACCAACTGGGTGTGATCCCTGATGTTGTTTTCTCTAGAATAGTTACTTAGTC GAAGCTTATTATAAGTAGGTAAGGGCAAAAGTCTCCAATTTACATCATTTTAAATAAATT AATATCTTGATAAAATGGTTCACTTTGAATTAAAATAAGTTTCATGATATCTATAGGTAT ATTTATCCTGTAACTAGAAATTAAAAAATGACCTTTTTATAACTATCATAATTTACAGCT ATCAGTATATTTTCATATATCATAAAGAATATATGAAAAAGTAATAAACATTTTCTATAA AAATCATTGTCCACAGAAATGCTTGTTATGAAATTTTAAAAATATGAAATGCAAACCTTT CCTCTAAGTAACAAAAGGAATCTAAAGACAATTATTTTACCGACTTATGACTTCTTTCAT GTCACTTGCACTCATTCCTTTGACAGCTCCATAAATTTCAAAATGTTCCTGCAATGTAGT ATCTGGCCACAAAGGGTTTATCTGAGGACAGTAACCCATACACTTCAGTGAATCATCATC TTCACTTGTCTCTGAAGAATAATCTCCTAAAAATACCTATAGAAACACAAACCAATTTTT ATTATTTTGCTTAATTTACACTGTGAAGGAAGTGGCAAGTACATTAATTAAAACCCCTTC CTACAGCCAGACTAATATCAAGTCAGATTTGTACTCCTTTATTGTCATTATTATTATTAT CACTAAGTAACTGAGACTACAAACATGTGCCACCATGCCTGGCTATTGCTTTTTTCTTTT TTGAATTTTAGGAGGGAAGATGTCTCACTACGTTGCCCAGGCTAGTCTTGAATTCCTGAG CTCAAGTGATCCTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGAATGAGCCACTG CACCCGCCCAGATGTTTTACTCCTTTTTGATGTTTGATGATGGAAGGACATATAAAGCTA AGTCAGAGTTCAGAGACTTGGTCAGAAAGGGTAATACAGAGTTGGATGAAAAAGCAAGAT GTAATTCTAATGATCAGGGAGCTTCACTGGAAGGTGACATTTGAGCCAAAGAGGTAAGTG AATTTAGTATATGTATTTCTAGGGTATAAGGTATAGCCAAACAAAGAAAACATCTTGGGC AAAAACCCAAAGAAAAGAGTATGCCTGGCATTTTCCAGGAAAGCAATGAGTTAGTGTGGC TGGCATAAAGTAAGCAAGGGGAGAGAAGCAGGAAATGGGATCAGGGTAGTTTTGTGAAGT ATCCACAAAGTGGTCAGTGACATGCTTATAATAAAAGACTAGCTGATGGCAGGTCAAAAC AAGCTCCCATATCTCCTGAAGCTAATAAAACTGTCTTCCATTAAGTTGGTAGACAAATAA CTCACGCATGTAAGCATTACAAAAGCAGAAATACTGTATATGCGTGTGTCTACATGTGTC TATGAAAATTTCACCATGCACATTATTTTTACAGATAACCCAAAAGATCATAATTTGATC AGGCTGTACAAAAAATTCTAAAAATATACATAAAAATTGAATATAAAATCCGAATTTGTC ACTAAAAGTTTATGTTAATTAACAATATAAATCACATTCAACATATCCTATACTCTTATA TATCATACCTGGCCTGAAGTTGGTTCAATATCACCAACCAGAATATTAATAATTGTGCTT TTGCCAGCACCATTTGGACCCAATAGTCCTAAGATCTCTCCTAAAGGAATTGAAAGAAAA AAAAATCATAATCAAATCATACTAAAAGTAGAAATTACTCTTCTAGAAAAGTTATGTAAG GAAAAATTAAATACCAGCCTTTTTTCACACAGAAAGAGATGTATTTAGTTGCCACTTTCT TTACTTTTCTTGAAAGAAGAAAATCTTTCTTGTCATCATATTCTTTATGCAAATTGCTGA CCATAATGGATGGTTTCTAATAAGAAAAATTGTATTTAAAAAGAAAGTTATAAAACTTAT CATGAAATGACAGGCTGCACATACCTCATATCCATATTACAAAAATTATATTGGCTAATA AGGGGATACTGTACAAATAAATATCCATTTATGACTGAAATTCTGGCTTATTCAAAAGTA AGTAAACGAAGTATTTTTTTCCAAGAAAGATTTTTTTCAGATTGCTTCATATGCAAAGAA AAATATTTTTCAGATTAATTTCTATATACCGGGAATTGATCATTTCATATTTACTATGAC TTAGCCATAAAGAATAAATTACCTCCTCACAACACTGGCAACCCATCAGCTCTTTGACCT TTAGTCTTTCAGCTTTGACATCTTCATCTTCATCCTCATTGTCTGGTGGTTCTGGAAGCT TCCTATTTTTAGACTTCGTTGAAAGGTTTCTACATATATATAATAAATATAAAAGACAGT AGGTTTTCAAATAATTAAAATAGTAAGAAATTCAGATACTAGGTAGAGAAAAGACTGAAA AAATACACTAACATAAGATCTAGGATTATCTCTGAAAGGTGGAATTATAAGCGATATTTC TTTTTTTTTCTTTCTTTCTTTCTTTTTTTTTTTTTTTAAGACAGGGTCTCACACTCTGTT GCCCAGGCTGGAGTGCAGTGGTACGATCTCAGGTCACTATAACCTCTGCCTCCTGGGTTC AAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGCGCCACCATGC CCGGCTCATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGCCCAGGCTGGTCT CAAACTCCTGGCCTCAAAAGATCCACCTGCCTCAGCCTCCCAAAGTACTGGGATTACAGG TTCAAGCCACCATGCCCAGCCACAAGCATTATTTTTCAATGACTGATAACATTTGGACGA TATTATCTAAATTCATTCATTTATTCAACAATATTATTTATGACTAGTAGGTGTCAGGTA TTATTACACAGAAAGAAAGATGAAAAAACATGAACCTTGCCCTCAAAAAATTTACAACCT GAGTATAAATGAAATTGCCCAGAAAGAGTAGATGTAGAGGGTTGACATCAGAACCCACAG TAACACCATTTTTAGGGATAGACAGAGGATGAAGTGCTTGCAAAGGCAATTTTGAAGTAC AGAGGCAAACAGAAGACATAATGGAAAACAAAGGAACAAGAAAAATGTGGCCAGGCGCAG TGGCTCCTGCCTGTAATCTTAGCACTTTAAGAAGCCGAGGCATGCAGATCACTTGAGGTC AGCAGTTCAACACCAGCCTAGCCACCATGGAGAAACCCTGTCTCTACTAAAAAATAAAAT ACAAAAATTAACCAGGTGTGGTGGCACATGCCTGTAATCCCAGCTACTTGGGAGGCTGAG GCAGAAGAATCGTTTCAACCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGTGA CAGAGTGAGATTCCATCTCAAAAAAAAAAAAAAAAAGAAAAATGTGTAAGGAGAACAATG TCAATCATATTAAAGCCTGCAGATTAGTTAAATAAGTTGAGCCTATTAGACAATGAAAAG ACAAAATCATTAGTTATCTTATTGAAAATAGTATCAATGGAAAGGTAAGGGAAAACCCAG ATTGCAGGGAGTTATAGGAGTGGATGGAAGGTGAGTAACTGGAGATAGAAGAATTTTGGC TATGAAAGGAAAGAGAGATATAGAATAGGAATTAGGGATGGATTCATGTTCAAATGAGAT CCATGGGTTCTTTCATATATGAAAGAAAGGTGACCCTCCCCAACCCCAAAAATATACCAC TGAGATCCAGAAAGGAAAGAGAAAAAGAGAAAAAAATACACTATTGAGATCTAGAAAGGA AAGAGAAAAAGAGAAAAAATACACTTTTGAGATCCAGAAAGGAAAGAGAAAAAGAGAAAA AGAAAATTGAGCAATATTCCAAGTATATAGAATAAATGAAGATTTGGGTAATAGGATGGA CTGCTGCTTCCTCTAGGACTGGGAAAAGGCAAAAATGATGGAAGATGTGAGTAAGTTTGT AGAAATTTATAACTTATAATTAAGTGCTTCTATTTTCTGAGATAAATGACAAGATTATTT ACTGAGAAGTAGGAAGTAAGATAAGGTGATTTGAGGAATACAAGGAATAAAGAGAAAGCT TTGAATAACTATTGAAAAGAAAGAGATAAGAAGGTGCTAACTAGGAAAATGTTATTCGTT ACCAAACAGTATTAAAATATAACTACCATTCAACCCAGCAATCCTACTACTGGATATATA TCCAAAGGAAAAAAAAAATCATTACATAAAAAAGACACCTGAACTCATATGTTCATCATG GTACTATTCACAATAGCAAAGTCATAGAACCAACCTAAGAGTCCATCAACAGTTGACTGG GTGAAGAAAATATGGTACATATACACCATGGAATACTCCACAGCCATAAATAGAATGAAA TTATGTTCTTTACAGCAACATGGATGGAACTGGAGACCATTATCCTAAGTGAACTAATTT GGAACAGACAATCAAATACCACATGTTCTCACTTATAAGTTCTCACTTATAAACAGACAA TCAAATACAACATGTTCTCACTTATCAGTGGATACACATGAACATAAACATGGAAACACT AGGACTGTGGACTCCAAAAGGGGGTGGGGATAAGGGTTGAAAAACTACCTATTAGGTACA ACGTTCACCATTTGGGTAATGTTACAATAGAAGCCCAATCCCCACCAGTATGCAATATAC CCAGCTAACAAACATGCACATTTACCCCCAAATCTAAAATATTTTTTTTAAAAAACCAGC TGAATTTATATGGAATAAATATGTAGTATTATCAAATGGAACTTTTATGTTATTTTTTCC AGCATATAATTCGATTCACCAATAATTATAATTTTTAGTGGACAGTTCGAAAAGACAAAA GTTGAGGATGCTGAAATGATAATAAAGTGATGAATCATGTAAGCAAGGCTGGATAGAAGA AAAAGTAAAAACAAATTAGCTAATATATTTGGAAGAATATGTAAAAAAGACAAACAATAA CAAGCATTGGCAAGGATGTGGAGAAAATAGAACCCTAAAACATTCCTAGCGGGAGTGTAA AATGGTATTACCACTTTAGAAACAGTCTGGCAATTCCTCAAATGACCCAGCAATCCCATT TCTAGGTATCCACCCAAGAGAAATGAAAATATATGTCCATACAAACAGTTGTATACAAAC TAGCAACATTGTTCATAATAGCTGAATTCATAGCAGCATTGTTCATAATAGTTGAAAAGT AAAAGCAACTCATTAAGATATATAAAAAGTGCTACACACGACTACATGATAAGCCCTCCA AACATTATACTAAGTGTAAAACCATATGCTAGATACTAATTATAGTGCCCAAATCCTAGC AATTTTTCAAAGATGTTATCTGGCAAATCTGATGATTTTCCAACATTAAAATAACATGCC AACCAACTATGGTAAAAAGCAAACAGATATAAAAGTTAAATACAAGGTATTTAAGAGAAT TGTTGGTCTTTTGACTCAAGTTTTCCAAAGCATATTTCCATTGTCCAGTTATATAAAGTG TTCAGAACAGGCAAATCTGACAGAAACAGAAAGTAGATTAGTGGTTACCTAAGACTGGGA GCTATGGGAATAGGGATAAGAAAGTGGCTGTTAATGGGTACAAAGTTTCTTTTTGGAGTG CTGGAAATGTTCCAAAATTATGTTATGGTAATGGTTACACAGTTCTGTAAATATACTAAA AACATTTAAAATTTTTAAAAAATCAACTGACCTGAAAAAGGGATCTTTTCTTATTGATCT GCCTCCATATTTTTTCTCATAGTATTGTAAGAGGAAAATCCACAGTACACACTGCAGGTA AGGCTAAAAGAAGAACATGTAGCAGCTCATGACTAAAAGATTTGTTGTTGTTGTTGTTGT TTTTTCCTTTGCCAACAGAACTAAGACTACATACATCAAGTTCCTTGCCATTACCAAAAG AAGTAATCACAACTTTTTTATATTTTACATGATAAAGATAATTAAAAATAAATTTTAATA CAAACCAAAGCAGAATTATTTTTAGCAAATTATTCACATATTTTCTGCCTCTGTATCATT CATTTATTGTCAGCTTCATAAAATATAATCGAACACAAAAACTTTGTTTTTGCTTCTAAG ACAGAACTGTAATTAAACAGAATTAATAACATGTAAAAGGCTAAGTATATTAAAGTGAAC ATATTCAGTAAATGAAAGGTACTCCCCACTGAAATACAGATTAGCTAGCGTTAACTAACA TGCTTAACTTTTTATGCACCTTCTTTTTCATGCAACAGGATAAAAAACTAAACATAGTTA AAACCATAGGACCAAACCATTCTTAAGGTACATGCTAATTCACAAAAACACTTTATTTCT TACCGATATAACAGCTACTGAAAGCCTATCCCATGGATTATAGGTGTCCACATTTTTTCG TACATTCTTCCAAGAAATCTAAGACAAAAAGATTTGAAAATATATACGCTGCAATATGTA GAAATATTTGGATTAAAATGAAAAAATGTATTTTGTTTAGCAAACGTGTACTTTCTATAA TAAGTTAGCTGTTCATATTAGTAAGTTATGTTTTTTACTTAAAATCTTCCCTGTCCCAAA ATATTTCTGAGGATCAGTATAAATTAAACACATTGAACTGAGACCTAAAAAGGGAAGCAG GGGTAGTAGGATTAGTAAGTAGAATTAATTAGCAATTCCAAACCAAGAATTCATAACAAT ATTTTTTCTAATCACATGGAAATTTCTTTCAATTATCCAGCCTTAATAAAATCAATCTGG TTTTTGTCTCTATTTTTTCTTGGAGAAAATCTCTTACACTTTATTCTTTCTCATCCCTTT ATAGTGAAATACGTTATTTAATCACTGATAAACTCCTAAAAACAAATACTGACTGAAACC ATGTCACACTTCTAATTATATACATCATTTTGAGCATGAGAGAACCTGTAATGAACATAG CCCTTTTCCTTTGAGAATTTACAGTTTGACAAGAGCTCACAATAATTTATGCTGCATTAA TAATATCTAAATCAAGTAGTAGCCATTAGCCCAATGCATTTTACTGTTTTCTATACAAGA ACTAACATCCCCAAATTAGACCATATTTATTTTATGTTTTTTAACATATTAAAATATTTA GCAGAATTACCTTTATGAAAGAAATCAGGCAACCTAGAAGTGGATAGATTGGAATGATGA TACAAAAGGCATAATGAAGAATAGTTGCAATTGTGTATCCCATAAAGAAAGTTATTTCAG TGATTGCAATACAAGCCAACGCTGCCTAAAGAAAAAAATAAATAAATAAAAGTGACAAAG TGTTTAGAAACTTCTTACAAATTGGTGTCTACGCATTAAACTATTTTTTCAATCCTCTAA TAAAACATGGAACAAGAGATGATATTTAGCCAGCAAGCAACAAGAATACCACTTGTTTGT AGCTAGTATCCTTGATACACTAGTTGCTAAATCTCTTCCATATTGTTCCTACGTGGAAAG GATGATTCAGAAGACAAATGTACACACAAAAAGAAGCTGCCAATTACCTATCTAAATTAT TCACTTACAAAAGACATGTAACATTTTTAGTATAATCAGGAAAGAATTCATGTTAATTAA ACTGCTATGGAAAGTTGAAATAATGTAAAATGTGACTTACCACAGAATAGATAAATGACC AAAATTCTTTGGTATTTAAAATTTTCTTAAAGGTGAAAGAAGCAATATAAGTGAACAGAA TAACTGATGGAACATAACCAATAAGGCAAAAAACCTGTAAATCAGAAATATGTTTCTATA AAAATATGAATAGCTTGCAATACACATGACATGAAATACTAGCCATATTAAAATATGAAA TTATTAATATAATCCTAAATAAATCATTTAAACTGAACACTACTTGTAGTTTTTTGTACC AAGTAAAATACTATCTCTCATTATTATAAAAAGCAAGTATAGCTAGCTACAACGTTCTCT CTCTCAAATATTAGCTACTATTTTAATATACAGCACTTTATTTTTTAATGTGTAAGAAAA ACATTATTATTTTATATGGCAGAAACTAATATATAAGGTCATTATGATCTCTGACAAAAT CGGTAAATTTACTTTCAGCATCAACCTCATGTAACTCTGTTTTCCCTTTTTCCTAATAAA GTAATCAATGAAAGGGCCTGCTGTCAGTCATTTACATGTGAACATGAATGCAAATCAGTC TCTTCTTTGATATTTTAAGCTATATTTTATTTTAAGTAATTTCTAGTTTTACTTTAGAAT CAGGGGATACATGTGCAGGTGTGTTACATGGGTATACTGCATGATGCTGAGGTTTGGGGT ATAATTCATTCTGTCACCTAGGTACTGGACACAGTACCTAACAGTTAGTTTTTCAACCCT TGCTCCCCTTCCTCCTGCCCCCGTCTAGTAGTGCCCAGTGTCTACTGTTGCCATTTTTAT GTCCATGTTTACCCAATTTAGCTCCCATTTATAAGTGGGAACATGCAATAGTTGGTTTTC TGTTCCTTTGTTAATTCACTTAGAATAATGGCCTCCAACTGCACCTGTGCTGCTGCAACA GACATAATTTCATTCTTTTTTATGGCTGCTCAGTATTCCGTGGTGTATATGTACCACACT TTCTTTATTCAATCACTGGTCAATGGGCTCCTAGGTTGATTCCATGTCTTTGCTATTGTG AATAGTGCTGCAATGAACATACTCATGTGTCTTTTTGGTAGAATGATTTATTTTCTTTTG GATATATACCCAGTAATGGGGTTTCTGAGTTATAAGGTAGTTCTGTTTTAAGTTTTTTGA GAACTCTCCAAACTGCTTTCCATGGCTGCTGAAGTTTACATTCCCACCAAGAGTATATAA GAGTATATAAGCATTTCATTTTCTCTGCAGCCTCGCCAGCATCTGTTGGTTTTGACTTTT TAATCATAGCCATTCTAACTGACATGAGATGGTATCTTACTGTGGTTTTGATTTACATTT CTCTGATGATTAGTGATGTAGAGCATTTTTTCATACATTTGTTGTCCATTTGCATGTCTT CTTTTGAGAAGTGTCTGTTCATATCTTTTGCCCACTTTTTAATGGAGTTTTGTTTTTTGA TTGCTGAATTGTTTAAGTGCCTTATAGATTCTGGATACTTGGCCTTTGTTGGATGCATAG TTTGTATTTTCTCCCATTCTGTATGTTATCCATTTACTCTGTTGATAGTTTCTTTTGCTG TGCAGAAGCTCTTTAGTTTAATTAGGTGCCACTTGTCAATTTTTATTTCTGTTGCAATTG CTTTTGAAGACTTATTTACCCATAAATTCTTTCCCAAGGTCCAGAATGGTATTTCCTATG TTTTCTTGTAGAATTCTTATAGTTGATGTCTTACCCTTAAATCTTTAATCCATCTTGAGT TACTTTTTACATACGGTGAAAGGTGGAGGTCCAATTTCATTCTTCTGAATATGGCTAGCC AGCTATCCCAGCACCATTTATTGAACACAGAGTCCTTTCCTATTGCTTATTTTTATCAAT TTTGTTGAAGATCAGATGGCTATAGATGTGTGGCTTTATTTCTGGGTCCTCCATTCTGTT TCATCGGTCTACATGTCTGTTTTTGTACCAATACCATGCTGTTTTGGTCACTGGAGCCTT TATAGTATAGTTTGAAGTCAGGTAATGAAATGCCTCTGGCTTTGTTCTTTTTACATGGAT TCCTTTTTTTTTTTTTTTTTGATAAAAAGTCTCTCTCTGTTGCCCAGGCTTGAGTGCAGT AGCACGATCTTGGCTCAACACAACCTCTACCTCCCCGGTTCAAGCGATTCTCCTGCCTCA GCCTCCTGAGTAGCTGGGACTACAGGCGCATGCCACCACGTCCAGCTATTTTTTTGTATT TCTAGTAGAGATGGTGTTTCACTATGTTGACCAGGATGGTCTTGATCTCTTGACCTCGTG ATCCACCCGTCTCGGTCTCCCAGAGTGCTGGGATTATAGGCATGAGCCCCCGCGCCCAGC TTATGTAGGATTCCTTTAGCCATCTGGGTACTTTTGGGGTTCCATATGAATTTTAGAATA GCTTTTTAAAATTCTGTGATGAATAATGTTGGTAGTTTGATAGGAATAGTGTTGAATCTG TAGATTGCTTTGGGCAGTATGGCCACTTTAATATATTGAGTCTTCTAATCCATGAGCATG AAATTTTTTTCCATTTGCTTGTATCATCTCTGAATTCCTTCACCAATGTTTTGTAGTTCT CCCTGTAGAGATCTTTCATCTCCTCTGTTAGATGTATTCCTAGGTATTTTAATTTTTTGT GGCTATTGTAAATGGAGTTGTGTTCTTCATCTGGCTCGCAGCCTGCCCATTATTGAGATA GAGAAATGTTAAGCTATATTTTAAACTATGGAATAAAAGAGCTTATCCTTTGTGAAATTA TTTTCAGGCATAAGAAAAACGAAGGAAGGCATTTTAAGGAAGGAATATATTAAAACGTTC CTGATTACACCCAAGTAGGTGGTCTACATGAAAGATCACTTTAGTTTCAAGAAATTATTT TAAAATGGTGGTAAGTTATTGTTTTTAAAAGTCACTTATCATATAAAATGATTACATGTA TTAAATACCAGACACACTTGCTCTATTTTCTTTAACAAATTAATAACCAAATTATGCAAT AAGTCAACTGTCATGTTTATAACAGATTTTAAATAACATTCTATCTATAAATAGCATGAG TACAACTAACGTTAACTTACCACAGCAAGGAACTTTACAGTATAAAAATATAATCCATAA TGAAATGCCAATAAGCTTCCTAGCATCAAAATAAGAATGATAAAAAATAAGGGGATATCA ACAACAGCTTGTCCAATCCAATATGCAGATGGCAAAAGACCTGAAAGTTTAAGTTGAGTA TAAGCTTTGATCTAAAAAAAATGAAAAACAATTTATTATAATTTTAGACACTTTAGAAAC ACACAAATAAATTAGTAAATTATTGTAGATCTCTTAATTTTACATCAGCAAAACCAAAAA GGTTACATTCCAGGCTTATAGGTAATAAAAGTCCCCCTCACACTAAATACAAATTCCATT TAGCCTTTAATTTGGCTCATTATTTCTGAGATGTAACAATTTCAACAAAATTTTTAAGAA TCAGAATACAGTAGTGCTGCCAAGAAACTGAGATTAAAATAAAGCAAAAGGTGTCATGGC GGTTGGGGTTACAGCTATACAAATAATAAATAGCCAAAACATTACTACTTTTGAAATACT GTGGAAACAGATGGGAAGACATGTTTACACAGAAAAAGAATTCTCAGTTTTAAAAATGAA CCTTTCATAAATAAAAACACTAATAAATTGCCAAGTATCCTTTGGATTTACATAAGGCTT TCAGCTTAAGTGAAAGCTTTTGAAATGTTCAAAGCCTTTTGTGTACACTGGTATAGCATA TAAATCTAAGGTGTTATTTACGTCACAAGTTTGTTAATGGTAAACTCAAATGATCATAGT TTTCCTATCTCATGTTCTCATTTAATTTGAAATTTCTAAAATATTTCATAAATCCAAATA CCTAACAATTTTATTTAGTTGATTTTTGTCATCTATAAAAATATCTACTCCTAATAACTG AAGGTATTATATGAAAGAGCTGTCCACAGAGATAAAGGAAGCATGAAATATAAAGATTAG TTAAGAAGAGGAGAAATGAACAAAATTGGCAAGTTTTCTGTTCAATGAATTATGAGAACA TGAGACACATGTAAATTCTAATACAAGAATAAAAACATAAGCTAAGGCAAATGCAATTAT TTTGGATAATTCAAACTTTTGTCATTCACACACTGCTGGTAGGGATAACATAAAATGGAA CACTCATCTTGGAAAATAATTTGGCAATTTCTTATAAAATTAACATGTATAATTCAGCAA TTGCACTCTTGGGCATTTATCTCAGAGAAATGAAAATGATGTTTACACAAAACCTGTATG CAAATGTCCACAGCAACTTTACAAAAGCCAAAAACGGAAAACAATCCAAATGTTCTTCAA CAGGCAAATGGTTAGAGAAAGTGTGATGTATCCATACCATGGAATATTACTCAGCAATGA AAAGGAATGGATTATTGATAAATACAAATAGGATGAACTTCAAAAAAAATGCTATTTGAA AAAAGCCAATCCCAAAAGAAAACTTATTGTGATGCCATTTTACATTTTTGAACTATCAAA ATTACAGAAATAGAGAACAGAGTAGTGGTTGCCACAGGTCAGAGAGGCTAGGAAAGAGCA AAAAATGGGAATCTTTTTGGTGACAGAAATGTTCTGTATCTTGACTGTGTCAATGCCAAT ACCCTGTTACATTGTACTATAATTTTACGAGATGTTATTATTGGGACAAAATGTAAAGAG TACACAGGATCTCTCTGTCATTTCTAACAAACAAACATGAATATACAACTATCTCAAAAT AGAAACTTTAATTAAAAATAAGTTAGTGGGTGCAGTGCACCAGCATGGCACATGTATACA TATGTAACTAACCTGCACAATGTGCACATGTACCCTAAAACTTAAAGTATAATAAAAATA TATATATATATAAATAAAAAAATTAAAAAATAAATAAATAAAAATAAAAAATTTATATTG GAAAAAAAATGTTTCAGTTGAAACAAGAAAGAAAATGCAAATGTCCAGTAAATTTTATTA TTGTGCAGTGGGTTATGGATTTCTATATTCCTTATACTTTTCTATAATTTATACATTACT ACAATGAGTATATTTAACAAAAATTGAATATTATTTTAAAAATAGAGATATGTGTTACTT TTATAGTAAACAAATAACAAAATTTTTATTAGAATGTATTTATTTATTTTATTTATTTAT TTATTTATTTATTTTTGAGATGGAGTTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGG CATGATCTCGGCTCACTGCAATCTCCGCCTCTCGGGTTCAAGTGATTCTCCTGCCTCACC CTCCTGAGTAGCTGGGATTACAGGCATGCACCACCACGCCCTAATTTTTTTTCTATTTTT AGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTAGTCTCGAACTCCCAACCTCAGGTGA TCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGGTCCACCACGCCTGGCC TACAATTTATTTTTTTAGAATTTATTAAAATAATGAGCTCATTATTCATCACAGTCTGTA AATTAATTTAGACAAATTTGTTTTTACTGAATTAAGATCATCCATGAAGAAGATCAGAAT TTTTATTAGAGCAGTAAGATATAATCTCAGCAGAGTGAAAAAGTGGGAGGCTTTGAACAA CCAAAGACTGTACAAGATCGCTATATGCCTGAAGGAAAACAAAAGGGAAAGGCGTAAAAA GAAAGTGAAAGAATACCAAAGAACCTCTGTATACTTAGCAATTTCTCCAAGGCCCTAATG ATGACAATCACTTTCATCTATTTTTTTTCCATTAATAAGAATTTAGCACCTTGACTACTT AATACCTCTGTTAAAGGATAAAAGGGACGGGCATGTTAGTTTGCCAGTTAAGAACATAAA GATCACAGTCACTTCCCAAATCCACAATTTAAACAAGTTGAGTCAACCTGAGCAAGTCAT ATGAACAATCCCATCTTTGATTTCCTGATCTATAAGAAATCAGTAACAAAAAACTTACCT CACAATGTTGTGAGAATTAGAGAATATAATTTTTAAAGCATGTAGCAAGTCTCAAATAAT AAATATTAATTATCACTTATTACAATAAGAAACTATAATAAATGTATTTATATTCCATTT ACTTATTTCTGAAATAACAATTATACTAAGCCTTGCAATCAAGCAAATAGGTTATTTTTA TATGACACTTCTTATTAGCAAATTATATATTTTTAACTGAGTCATTACCTTATGATTCTC TGCATTTTCCATGGCAAAGTAAGGTGGCATTGCAGTAACAATGATTCCAAGCAAAGCTGC TTGAAAATACAGCTCAATTTTAAAAACTATATCAGTAATTTCCTGAAAGACAACCACAGA GTAACAAATGGAACTGAGAATCATTTTATATCTTAAGATATATCTTAGGATATATCTTAT ATCAAAAAAAAATCAAAACCTCAGAAAGAATGTATTAGAATATCTAACCCAGGCATAGTC TACATGAAAGAATGAGTGGCAGATGTATTAACAGGTGGTTGTGGACAATATTACCAACTC TGCCACTTATTAATAACTATCTGATCCTAAGCAAATCATTTTACTTTCATTTTCCTGTCT ACAACACAGAATAATCAGGCATATAAATTACGCTTCACAATTTCATAAAAATGAATGATG TATTTGAAAAGCAGTTAGTATGTCCACCATAGTGGTCCTATGAAATAATAATAAATATCT AAGAATGATATTTGTTGCTCTTGTCTTTTTAATTGGGAAAAGCTATATCCAAGCTCAGCT TCCTATGGAACTAGAACTTCTTCTCCCAAGCAGAAGAGGAATTAACTCCCACAGGCCCCA ATGTCGTTAGCTTCCCCAGGGATCCAGGTGCAGTCAGCTAACTTTCCCAGACAATCAATA AACAGCTAGCACTTCAAATGCAGATTACCCAAGTCCAAGGATACTATATTATCAGCCACC CTCACCAAGGTCAGTTTCCTCCCCTTGTTCTATAAGAATACAGACCCGTGGGACAGAGAA GGTACTCTGCACTGGAATAGAATCCGCAGTGCCTAGCAGATACCCTCGCACTGGCACACC CCTCCATGGGATGACATAGAGACAGAGTACATCACTGTCTTGCTGAAACCTAGCCTTCTG AGTTTTCCTATTTAGCAATTAAGTCAATTCCAAAGTTCAGGTCATATGACATTGCAGAAT TTGTCTGAAACTCTCGTAATATGACAGTGGAGGCTCAGAAAGAACCCACAAATATGTAGA CTAGTAGTGCAAGAAGTGGAAATGAATGAGACTACAGTTGGATCCAATCATACAGAATCT AATGAAGAAACAAATTTGAAATATTAATACGACTATATATGAATAGTTAGCTTCAAAAAC TCCCATGTATTTCTTTCGAAATATAGTATGATTATATGTCAGTGTTGTTGAAAATTGTAA GTTGTAAAATCTTGTGTAATAGTTATGGATACAGACATATGTAGTAACATCAAAAAAACA CGTATGGGAATTACAAATTGTGAAATTGTGAATTGCGGTTACTCCTACGGAGGAGAGAAG GAAACAAGATTGGAGAGGGGTAACATGAGTTTTCACCTGTGTCTTAAAAGTTTTACTAAA AACAAATATTATGCAATATTAACATTTGAAATATTTGGATAGTAGGTGGTTCGTTTTCTG TACGTTTGAAATATTTCATAATATGAGATACCTCTCCACAGACACTGCTGCTGGAAATGG AAAATGATGCAACCATTTTGGAAAGCAGTTTGGCAGTTCTTCAAGTGTTAAACATAGAGT TACTAGATGATCTAGCAATTCCACTCCTAATTATATATCCAAGAGAAATAAAAACATATG CTCATACAAAATCTTCTACTCAAATATTCATAAGCATTACTCATAATAGCCAAAAGGTGG AAATAACCCAAATGCCATCAACTGATGAACAGATAAGTAGAATGCAGTATTTCACATAAA CATTCCATACATTCCACACAATGAAATATGATTTGGTAGTAAAAATAAATGAAGCACTGA TACGTGTTACAAAACAGATGAATCTTCAAAGCAGTATGCTAAGTACAAGAAAGCAGACAA AAAAGACTACATACTGTATGATTCCATTTATATAAAATGTCTAAAATAAGGAAATCCATA GAAACAGAAAGTACATTAGTGGTTGCCTAGGGTTGGGAGTGGGTATGAGAGGAAATGAGT GATTACTAATGAGTATAAGGGTTATTTTTTTTGGAGGGGGGTGATGGCATATTTAAAACT GACTGTAGTGATGACTGCACAACTCTATAAGCATAATAAAAGACACCGAAGTGTATACTT TGAATAATGGTCAGGTTGATTGGGCATTATATTTCAATGAAGCTGTTTTTAAAAGTATGA AAAGAAGAAGATAGAAAATATTGTTACAGATATTTGTCCATTTATTTTTTAGCATATGAA AATCAAAAGGATTAAGAGAAAATATGTTGGATACTTTTCTGTAATCTTGATTCTGATATG TACAATCCAACAGTTCTATCTAGAGGAAAAATGGTTGCCTGGGTGACTTCTCAAGTTTTT TTCAATACCCAATACCTGGATTTTAGGTAAAAAATATTCATTTAAAAATTATCTTATATT TTATTCTATGATCAATATAGAACACACTTATTCCTTATACAAATATTAATACCAAAACAG AATCTCCTTTACCCTGAAACATACTTCTACTGGGGAATCCTAAACCTTAATGTAAACCGT TTCTCACTTGAGTTTTAAGAAGTCTAAGAGATCTCACAAGATAAATTTCTACATATTTTG TTATTTTTGCTTAGTTTTTAATGGTTATTATATATATGACATGCATATGGAAATTTATCT GTATATACATTGGCTTACTTGAAAGAATGGGGTACTCCAGATCTGGATGGTTTCAGTCAC ATTTAAATGATAAAGATAGTAGTTACTAATGATATTCACTAATATAGGTAAAGAATAAAC CATAGTACTGTTGAAAACAGCTGCAAAAACATAGTCCTACAATTAAAAAAAAGACACTTA TTACATACTGTATATAAGCGGATATATTATTGATATGTACCAAGCTTTTCTCACCAACAA AGCTAATTCTCATACAGAAAAACTGCTTCAACAACTCACAGAAATAATACTCAATGACAG ATAAAGACAATCTGGTTTGGAATGTACAGATATTTTAATATTTTAAACAAGCATATAATT TTTTAAAAAACTAAATTTCTGTAACTTTATATATTGGTCATCTGTGAAGTAATGAAATAT ATCATAAATAAAGACAGCTAGTTATTTCCAAAAGTAAAATCTAATTTCTAACTCATAAGG TCAAATCAACAAATAATTAATTTTAGAAGAAACGTTTTAATCTTGCATAACTCCCAAATG GATATTCATTCACTGCATTCATCTTACCTTTTCTGAATGCATCACATTTAAAGCCGCACT ATGGGGAGCCACGGATACATAGTCACTGTCATTAATCATCGTCACCATTATGTTCTGGCT TGTGAAAAAGCTAATAAGATCACTGATATCTGAGTCTGGTGTTAGAAAATAAGCAAATAA TAAAAAATGAGTCTAAACGAGGCTTTTAGTAACACTGGGAAGATAATTCTATTTTTAGAG AAATATTTTATTTTCATTAGCGAATACGCAAGTAAGTACATTGGCTCTGAAGCCAGTCAG CCTGGTTTTAAAGTTGAGTTGTAACATTAAACTATTCGTCCTTCAAGCAAGTTACCTAGA TGTTCTGGACCTTAAGTTCCCTCTTTTGTAAAGTGGGTAAAATAAGTATATCTGCCTTAT AGGTAGAGTGATCATCCTGAGAATTAAATGACTGAATATATACACAGAGTTTAGAACCTG ACACATAGTAACTGCGCATATTTTAGCTGCTGCTGCTGCTGCTGCCACCACTGCTGCTGC TGCTACAACTATTATTAACATTGAAAAGTTAACCTATAACACATGAAATTTGGTTAAATA ATAAGAATAAAAATCTATCTGACAATTTTAGGTAACAAGATAACCTGCTAAGTTCAGAAA GGTATAGGTGTGGTAACATCACTCCCTAGAGAATTTTTTGTAGGCTCTGGGCAGACATGT CAATTGCCTTAACTACCTTAAAATATTCAAACACATAATCACATCTCTACATTCTCTAAA GTACCTGGAGCCAAGAGTAAGATTTTAAATCCTGTCGGGATTTAAATCTATACCAACATG TCTGCCGAATAGATGCAGTTTCTCCTCCATCATAACAAAAATCAGGATTCAGGGAAGGAC AAATGTGACTTTAGAGAGAAATTTAAATCAAACAAAGCAAAACATTACTAGTAACTGAAT AGTATGGCAGGGTGGATCAGACACAGCACTAGATCTCAGTGTCATAGAGAATGGTGACAC TACTTTACTCCCAACCTAGTACCTTAACTGATCTCTTATCTCTAACTTGCAAGACCAGCT ATGTACCCTGAGAAGAGAGACACATTATAAGTGAAGGAACCACAGCACAAGAGATACAAA AAGCTCTGCAAGGTGGGTAAGATACCACCCAATATATATACACACAGAGGCCAGTGGTTC AAAAAAAAGTGGTTTTATTTTGGAACACACACAAGGCTTAGGAAAATATGGCATGCATAA GCAAGCAACTCTAAGAATAATAAAAAATTAAGAGACAAACTGAAAATACTAGAATTTCTG CAGATCAATGAGAATTAACTCAAAGCAAAAAGATATGATTTGAATCCAAGTTCCTTTAAA AAAAAAAGAAATATTTGAGATACATGTACAATTCCCTGGACACATATAAAAAATGTCAAG ATTAGCACAGTGTAAGGATTATATATTAGCAATATAAAATGTATTTTAAAACCAAAACGA GAATTCATAATGAAATTTCCTAATGAAAGAAAAAAAATTGCAAAACCTAACATTTTCCAT TCGAGTAATTTTCCATTAATTTTCCATGCTCCAGGTAATTTTCCATGTTCTCACTCATTT ATCCATCAATAAATACATCTTTACCAGAAAGAATGAAGGTTATGTAATATAACACGCACC AGATTTTAACAGTGATTATTTTAATACTAATTTATAATCATTCCTAGCCATGCTTATTAT TTTAATACTGGGCAAAGTCTTTTTTGAATTAGTGAATCAAAAAGGAATGATACTAGAATG TAGGTGAAGTGTTAGAAAGGTTAAACCCCAAAGAGTCTGCTACAGAATAGGAGATGTTAT AGGAACAACTGATCACATATGAATAAAGTTTGTATTAGCTTTTAATATTTTGAAAATCAG AACACTATGTCAGTTTTTTGTTTTGAGCTTTGCTCAAGTCTGTATGTTTAAATTTTTTTC ATATTTGACAACTACATGGTAAGAATACTAATAGCAAAGCCAAAAATATCCATTACAAAT CTAATATATTCAATTAGAGATATTTATATTTAAGTCTTATTTTTCTTAGTTTTAACTAAT TCTTCAGACTGTCCTTGAAGAATTAAAACACTTCTATGCAGACACATACCTGTATAAATA TTATGTACTACAACTCTTTGTAAAGAGGGTTTTTCAACTTTTGAAGTATATTTTGCTCAT CATGGACTTATCAGCATAAAACATGCTAGTAAGAATAACGTTATTATTAAAAAAGGAAAT TCTACTATTATACAAAGTATAAATTTTTTTAACTATTTATTTATTTATTTATTTATTTTG AGGCAGAGTCTCCCTCTGTTGCCCAGACTGGAATGCAGTGGTGCAATCTCGGCTCACTGC AACCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTACCTGAGACT ACAGGCGCGTGCCACCATGCCTGGCTAATTTTTATATTTTTAGTAGAGACGGGGTTTCAC CGTGTTAGCCAGGATGGTCTCGATCCCCTGACCTCAGGTGATCCACCCGCCTTGGCCTCC CAAAGTGCTGGGATTACAGGTGGGAGCCATCGCACCTGGCCAAAACTGTCATTTATTTGT AAACCAAAATTTACTGTAATATATTCTTCAGCATCAATAAGATACGTATTGAACTATAAT TTAGATTTCATGCAGACAGACCATGCCTTTACCTTAAATATAGTTTTAAAATCCAGACCT TTATCCACCCCTCAACCCCATGCTCCATGCCAACACTCGTTCACAGACCTTCACACACTC TCACCAGCAGAATTTTGAAGAAGCAGACTTGTTTTGTATTTATGTGGTTTGTCTCCAGGT TTTAGAAAATATAAGTCTGGAACAAGTTTGATGGGAACCACAGCATTTTTAAAAGAGTGA TGAACCAAAAACATAAAAATCTGAACTGTGAAAAAAATTAAAAGCAGAAGCAACCTGAAA AGAAAAAAAAAACAACACAGCTCAGGGTACAAAGGTACATTAATATGAAAATCAATTAAA ACTCTCCCTTCACATTGATATGGACTTTTTTTGTTTTTATTTGAGACAGGGTCTGGTTCT GTCACCCAGGCTGGAGTGTAATGGCATGATCTCAGCTCACTGTAACCTCCACCTCCCAGG CTCAAGCAATCTTCTCCCCTCACCATCCCAAATAGCTGAGACTACAGGCACACGCCACCA TACACAACTAATTTTTGTTATTTTTTATAGAGATGGGGTTTCGCCATGTTGCCAAGGCTG GTCTCAAACTCCTGAGCTCAAACAAGGAGCTTGCCTGCCTCAGCCTCCCAAAGTGCTGGG ATTGCAGGTGTGAGCCACCTTGACCAGCCTACATTGGTATAGATTTAAACTCTAGATAGT TAAAAGATAATCACTGAAAAAAACAAAGAAAAAAAACTGAAAAAAAAAAATAAGAAATCG TATTCCCCAAAATGATCTTATGACAATACTGGAGAGAAAGCCAATACTGTACGACAAAAT TAAAAGTTATAAAAGTGTATTTTAGATCAGTGATGCCCTTAAATTTTTCTAAGAGTATGT AAACACGTAGTTATAACTGTTAAAACACAAGACATTATGTCTCAAATATTTGTCTCTACT CCTGAAGGAATTACTTCCTGTCCTGTCTCTATCTTAACCATTTACTTTTTTTTTTTTTTT TTTTTTTGAGATGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTCGG CTCACTGCAACCTCTGCCTCCCAGGTTCAAACGATTGTCATGCCTCAGCCTCCCAAGTAG GTGGGACGACTGGCATGTGCCACTGTACCCGGCTAATTTTTGTATTTTTAGTAGAGACAG GGTTTTGCCATGTTGGCCAGACTGGTCTCAAACTCCTGGCCTCAAGTGATCCAGCTGCTG CAGCCTTCCAAAGTGCTGGGATTTCAGGTGTGAGCCACTGCACCCAGCCCCATTTACTTT TCACGTAACAAGAAAAATATTTTAGATATAGAGAAGCAAATAAAAATACAATTAAACTCT GAATGGCTGATATCTTTGAAATCTCATCCTAATCGCAATTTTATCATATTAATTGCCACT GCTGCTCTCAGGAGGCAAAGCAAGGTATACTACAATGCCCTTTTATCTGAAGAGCAGCTA CTTATCTGATAAAATATCTATATATCACATGTAATAAGTGTCCTAACAAGCAGTTGGAGA GCTTAGATTATCATACTTCAGCAATTTATAAATTTCACATACCCCGTAATTTTTTTAAAA AAATTCTTAAATTGTTATATCTAAGATTTCAAAAGCATATGGCATTGATCAAGTTCCATA ATAAGTTAAGAAGTGATTTAGGTTAAAAAATATTCACAATTAAATAATATTTGGAAACAT GAGGTTAAACAAAGTTGAAGGAATTTCTTTACCAGAGAACATCTCATGTTTTTTATGCTA ATGAATAACTCTTTAATATAGGGAATATAAGAGTAATATTTTCTAAATGTATTTGACCAT GGAACACATTTTGTTATGGATTGAATGTTTGTGCCTCCCCAAATTTGTATGTTGAAGCCC TAACTCCCATATGATGGTATTTGGAAATGGGACTTCGGAAAGGTAATCTGCATCAGATGG CATCATGAGGGTGGGGTCCCCATGATGGGATTAGTACATTTATAAAGAGACACCAGAGGG TGCATGCCAGTGTACATGAAGAGGTCATATGAGCACACAGTGAGATGGTGGCCTTCTGCA AGCCAGGAAGACAGCCATCACCATGCTGGCACCCTGATCTCAGAACTGCAGCCATCAGAA TTGTGAGAAAATAATACTCTGTTTAAGTCACCCAGTAAATGGTATTTTGTCATGGCAGTC AAAGCTGACTAAGGTATTTTAATTTTCTTTTTTTGGGGGGGCGGGGGGGCAGGGACGGAG TCTCACTCTGTTGCCAGGCTGGAGTGCAGTGGCACGATCTTGGCTCACTGCAACCTCCGC TTCCCGAGTTCAGGCAATTCTCCTGCCTCAGCCTCTCAAGTAGCTGAGACTACAGGCGCC CACCACCACACCCAGCTAATTTTTTTATATTTTTAGTAGAGACGGAGTTTCACCATGTTG GCCAGGATGGCCTTGATCTCCTGACCTTGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCT GGGATTACAAGCTTGAGCCACCGAGCCCAGATGGTATTTTAATTATTTTTCTGAGTGTAT TTTATGAGAGTGGTGTTTAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCA TAAAAAAGGATGAGTTCATGTCCTTTGAAGGTACATGGATGAAGCTGGAAACCATCATTC TCAGCAAACTAACACAGGAACAGAAAACCAAACACCACATGTTCTCACTCATAAGTGGGA GCTGAACAACGAGAACACATGGACACAAGGAGGGGAACATCACACACCGGGGCCTGTTGG AGGGTTGGGACTGGGGAGGGATAGCATTAGGATAAATACCTAACGTAGTGATAGGTTGAT GAGTGTAGCAAACCACCATGGCACATGCATACCTATGTAACAAACCTGCAAGTTCTGCAC ATATATCCCAGAACTTAAAGTATAAAAAAATAATAAAATAAATTGAAACATGCTGATTTA AATAAACATTTTTCTTTCAGTAATGCCGACCAGGGAATAAATCAGATACGTGATTGACAT TTGTTTGACACTGAATTTGGTCAAAGAAGAGCATATAAATTTAGCATATTCCAAACATAT AACAATATTCTTAATCTTAATGATTAAGCCTTATTACTACTGACATTTTGGACTTAACAA GATAGGTGTGTGGTATATGAAAGTGGTTAATGTTATTTCCAAATTATTCAGTTCCTAGTA CCCTAGGAGAACCTAACTGAGAAGGGCTAAAGCTAACTTGAGATGTCATTTTGATCCCAG ATCTACTAGCTATGTAGCCTTCTTTATTTTTCAGTTTCCTCATAGGATAAATAGAGGTAA AACTCATTTTTCCTGCTACTTACAAAAAGTGGTTATAAAAACTAACTAATAGACGCAAAA AATAGCGAAAAAATAGAAACGCAAAACAAAATTTAAGATACAATGGGGAGTGTATTAATA TATTCAAGGAAACTTGAATCTGTGCTCCCAGGTGAAAGAAAGAAAAAGATACAATGACAG TAATTAAAAAATTATACAATTAGGGAATATTTGTTATTTCCTCACTTTATAGATGAGACA ATAAATGCTAGTTTAAAAAGTGTAAGACAGGGTATTCGATGAAATTATTGTAATTTTTTT CTCTAACATTGTGAAATTACAGTGGTAATCTTTCGAAACTATATAAATTATTTACATATG TTAACATTTTAAAAATTAAGATGGTAAAACCAATGTGTATCCTTAAAAAGCAATCCATCA GGTATAAGGGTGATAATTATACTTACACTGATCTCACTGATTTACTTTCACGTTTCAAGG TAAAGAAATGAAACTTTGCTATTGTATACATCTGTTGTTTCCAAAGGCTCATGGTGCTCA CTAGAGCAGCCTTGGTTTCAGAAAGAATAAGTAAGCTCTGTTCCATTTCATCAAAAGATT TTGAATCCATTTCTTCCTCCAGTGGCTGCTGAGTAAATACACTATAATCTATTTGCCAAA ACAAAACAAACATTTCAGTATGTTCATTAAAAAAGATACAAACTTTCTGAAGCAGGAACA TTTAAAGAAGCATTGGTCTGGCAGTTATGTGGAACAAATGGAACTCTCTTATATTCTGGC AGTATCTATTAAAGCTGAACATATGTATATCTTATGACCCAAGAGATCCCCAACAGGTAT AAACCCAACAGAGATATGAATACAGGTTTCACCAAAACACATGTACAAGAACATGAGAAT GTTCTTGTTCTACTAAGAACAAGAACACTATTCTATGGAATAGTGTAAACCAATGAAAAT GAACAAACTACTGTACCCATAACAACATGGCTGAACTTCACAAATGTCATTTTGAGTGAA AGAGGACAGATGCAAAGGAGACACATGGTATAATTCCACTAGTTCAAAATCAAACTGGAT ACATATCCATATTTAAGATCTTATTATCTCTGTATCTGTATAATATCCAACTTTTATGTG AACTTTTCCTCTCTGACCACAACTTAGCATCATATCCTGATCATACACGAGACTTCTCTC TTATCACCATGTTTGAGAGTCCTCTCCTGGCTTTACATTACTTCTCAATTAAAATTTAGC CTCAGGCTCAGTTTTCAGCCAAATTCTGCCCTTCAACTTCATCTTTAGTCTTTGGAAGGT TTAAGAGCCAATGCCTACTTCAATATAATTTCCTGGGATTACTGAGGTTGTACATGATCA ATGACAGTGTGATCATACAGATTATTAGCACAACACTTAAAAGGTATAACAAATTCAGTA GTGTGAATAAGGTATGTCATTCAGATTTCATTTTAATATTTAATATTCATTTAAATTACA GTTAAACATTCCAAATGTATTTGGAATAAAAATTTATTTACGTACTTTATGTTAAAATTC TAGCATATAAACAGAGCCAAAGACAAAAACCACATGATTATCTCAACAGATGCAGAAAAG GCCTTTGACAAAATTCAACAACCCTTCATGCTAAAAACTCTCAATAAATTAGGTATTGAT GGGACATATCTCAAAATAATAAGAGCTATCTATGACAAACCCACAGCCAATATCATACTG AATGGGCAAAAACTGGAAGCATTCCCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTC TCACCACTCCTATTCAACATAGTGTTGGAAGTTCTGGCCAGGGCAATTAGGCAGGAGAAG GAAATAAAGGGTATTCAATTAGGAAAAGAGGAAGTCAAATTGTCCCTGTTTGCAGATGAC ATGATTGTATATCTAGAAAACCCCATCGTCTCAGCCCAAAATCTCCTTCAGCTGATAGGC AACTTCAGCAAAGTCTCAGGATACAAAATCAATGTGCAAAAATCACAAGCATTCCTATAC ACCAACAACAGACAGAGAGCCAAATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGA GAATAAAATACCTAGGAATCCAACTTACGAGGGATGTGAAGGACCTCTTCAAGGAGAACT ACAAACTGCTGCTCAAGGAAATAAAAGAGGATACAAACAAATGGAAGAACATTCCATGCT CATGGGTAGGAAGAACCAATATCGTGAAAATGGCCATACTGCCCAAGGTAATTTACAGAT TCAATGCCATCCCCATCAAGCTACCAATGCCTTTCTTCACAGAATTGGAAAAAACTACTT TAAAGTTCATATGGAACCAAAAAAGAGCCCGCATCGCCAAGTCAATCCTAAGCCAAAAGA ACAAAGCTGGAGGCATCACGCTACCTGACTTCAAACTATACTACAAGGCCACAGTAACCA AAACAGCATGGTACTGGTACCAAAACAGAGATATAGATCAATGGAACAGAACAGAGCCCT CAGAAATAATGCCGCATATCTACAACTATCTGATCTTTGACAAACCTGAGAAAAACGAGC AATGGGGAAAGGATTCCCTATTTAATAAATGGTGCTGGGAAAACTAGCTAGCCATATGTA GAAAGCTGAAACTGGATCCCTTCCTTACACCTTGTACAAAAATCAATTCAAGATGGATTA AAGACTTAAACGTTAGACCTAAAACCATAAAAACCCTAGAAGAAAACCTAGGCATTACCA TTCAGGACATAGGCATGGGGAAGGACTTCCTGTCTAAAACACCAAAAGCAATAGCAACAA AAGACAAAATTGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAA CTACCATCAGAGTGAACAGGCAACCTACAAAATGGGAGAAAATGTTCGCAACCTACTCAT CTGACAAAGGGCTAATATCCAGAATCTACAATGAACTCAAACAAATTTACAAGAAAAAAA CAAACAACCCCATCAAAAAGTGGGCAAAGGACATAAACAGACACTTCTCAAAAGAAGACA TTTATGCAGCCAAAAGACACATGAAAAAACGCTCACCATCACTGGCCATTAGGGAAATGC AAATCAAAACCATAATGAGATACCATCTCACACCAGTTAGAATGGCAATCATTAAAAAGT CAGGAAACAACAGGTGCTGGAGAGGATATGGAGAAACAGGAACACTTTTACACTGTTGGT GGCACTGTAAACTAGTTCAACCATTGTGGAAGTCAGTGTGGCGATTCCTCAGGGATCTAG AACTAGAAATACCATTTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGACTATA AATCATGCTGCTATAAAGACACATGCACACATATGTTTATTGTGGCACTATTCACAATAG CAAAGACTTGGAACCAACCCAAATGTCCAACAATGATAGACTGGATTAAGAAAATGTGGC ACATATACACCATGGAATACTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAG GGACATGGATGAAATTGGAAATCATCATTCTCAGTAAACTATTGCAAGAACAAAAAACCA AACACCGCATATTCTCACTCATAGGTGGGAACTGAACAATGAGATCACATGGACACAGGA AGGGGAACATCACACTGGGCACTATTGTGGGGTTGGGGGAGCGGGGAGGGATAGCATTGG GAGATATACCTAATGCTAGATGATGAGTTAGTGGGTGCAGCACACCAGCATGGCACATGT ATATGTATGTAACTAACCTGCACAATGTGCACATGTACTCTAAAACTTAAAGTATAATAA TAAAAAAAAATAAAAATAAATAAATAAAAAAATAAAATTCTACCAATTAAACCATAAACA TATATTTATTTAATGGCAAGAATAAAATACTACACAATTGAGGTTTATTTTAAACTCAAA AACATTCAGAACTTTCAACACAGAAAAATATTAACAGTTAATGCAAATATTAAAGAGAAT GTACTAGTGAGATAACTTTAGGAAGAACATTATAACTTTTGGGCCAATACATGTATTTTT TAATTTAGATAATAATATAAAAAGAAATCAGATTATATAATATTAATTTTATGTAGTGGT TCAGTATATTAGTACTCAAGATATTAAAACAAATTTGGGAGACTTGCTTCTTTTTTTAGT TATTTAATTCCATTAAGGCCACGCACTTTCAATATAAAAGTTTTATTGTGGATTCTTCCA CAATTTGTGAGGGTGAACTAAAAGCAGAATGCCCACTTCATCATTTAAAAATTTCAAAAG AAGGAGAAACTACAAAATCACATACATTAATTTTCAGATAAATCTTCTTTGATCCAGACA TAATAACAAAAGAAAAATTAAGAACTCAAAAATATATGGCTTCTCCTCACTGCATTTGAA AGTGGGCATCTGGTATCATAAACGTAGGACTACAGGAGCAACTTTACAGTTAGCAATGCT GACAAATTATTGTTCCCACACAATAAGGCCAATCTTTTAAAATTTGACTACCAAACCATG AATAATTAAATTCTAGTAATATTTTAAGTTCCAGATTTATTTTAGCATAATATAAGCAAG TTTACTTCATGATGATATATTCAGCTTGATTCTTGACTTTGGTATCACAATGATTTTAAT CATCACCCACTCGGCATTCATGCAAAATGTGTATTTGCAGCATCTCAACTCTTTTAACAA CTGTGAACTAACATCCTGGTTTCCTTTGCTCTCCTCACCTGCCACTACAAACATTTTGCT AACCTTCGATCATAAGAAAGTTTCCTCAACTCATGTTCTTACCGTAAACTGAATAGATCC ACCTTGCTCCTTACTGCATCATGAAATTGATCTGTCAAGATCACCACTCTTACAGTCTAC CAAATCCCTCACCGTCCTCTGTTACCAAAACTACCTTTTTTGTCCTCATCTTATTCTTCA CAGCAATTGACAAATAACTGACCACTTCCTCTTTCCTAAACACCATTTTTCTAGGTTTTT CCATTTCCACTCTTTCATGAAAAAGTAGAGTAATAATTGCTCATTCACGGTCAGCCCTCT TGGCTCCTTCTCCACTGCTCACCCAGGAGGCTTGCCCCTCAATTCTTATCTACACTCCTT ACCCAACTAAGAGATTTCATCCAATTCCATAGCACCATCTACCTGTGAGTAACTTCCAAA TCTGTATCTTCAGCCGTAACATCTTCATTTAACTCCAGATGCATCTCAAACAATATACTC AAAATTCATGCCTCGGCCGGGCGCAGTGGCTTACACCTGTAATCCTAGCACTTTGGGAGG CCAAGGCGGGCGGATCACCTGAGGTCAGTTCAAGACCAGCCTGGCCAACATGGCAAAACC CTGTCTCTACTAAAAAATACAACAACTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCCCA GCTGTTTGGGAGGCTGAGGCAGCAGGAGAATCACTTGGACTTGGGAGGCGGAGGTTGCAG TGAGCCGGGATGGTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCAAAAAAAAA AAAAAAAAAGGAAAAAACTCATGCCTGCATTCCTTCTTTCCACAAACCTATTCTTCCCCT ATTTTCAGGAAATGGCAATCTCATTCCCAGTTATCAAAAGCTTAGGAATTATTCTTCATT CCAACTTCTCCTGAGCCTCTAACACTCAATCTATCAGCAACTCATCACCACTACCACCAG TATAACCCAAATATCTGTTCTTTCCCTTTTTTTTTTTTTTTTTTTTTTTTTAAACAGGGT CTCCTTCTGATGCCCAGGCTAGAGTGCAGTGGTGCAATCATGGCTCACTGCAGCCTTGAC CTCCTGGCCTCAGGTGATTCTCCCACCGCAGCCTCTAGAGTAGTTGGGACTATAGGCACA CACTACCATACCTGGCTAATTTTTGTGTTTTTTGTGACAAGGTTTTGCCATGTTGCCAAG ACTGGTCTGGAACTCCTGGGCTCAAGCGATCTCCCTGCCTTGGCCTCCCAAAGTGCTGGG ATTATAGGCATGAACCACTGCGCCCGGCCTCCCTATTTTCACTGACACCCTAGTTCAAGA TAGTATTAACTATAGCAGTTTCCTAACTGGTCTTCCTACTTCCACACTTCCTTTATAATA CTCTTATCATTCAACAACCAGAACGTGTTTTTTTAAAAATTCAAATCAGATCATGGTACC TATTTGCTTTAAAACTCTCTGATAGCTTCCACACTACAATAGGAAAACAAATGAAATTGT TTTCCAGACGTTCAAAGGCAGAACATGATCTATCCCTTTGAGTATCCTCCTGACTTTGCT GTGTAATAGCTTCACTATGGCTCCGGCCATGGTAGCCTTTTTTTATCCCTCAAAGACATC CAACTCATTCCTCAGTTAATACCTTTGCAGTTGCAGTTCTTTATCTGAAAATTTCTGCCC TAAAATCTTCACCTACTTGATTTTTCTCATTATACAGGCCTCAGGTCAAGTATCATCTCA ACAAAGTCCTTCCTGATGATATAATCTAAGTTCGCTGCCTTCTAAGACCACCCCATTATT TCCTGCATTACTCCTATCACTATCAGTATCTCATTACTTATTTACTTATTTCTACCCTTT ATTCTAAAAAAAATATAAAATTACATTTATATAATTTTTGTCTTATTCACCATCTGTCTG ATTCATTGCCTAAAATGTTTTGTTAGTTCTGTTTTTACCTGCTTGGTCAATTTCTGCTTC AACTTCTAGCTTTAAAAATACGTCTTCCAAAGTCGTCATGGAAACACCATAAGAAATGAC ACCCAAATTTGAATGACTGTCTAGGGCAGAAAACAAACCTAAAAGAAAAAAATGAAAGAA TAGTATATCTTTAAGCATATTATCATAAATTATTGTAAAATATCCTTTAAAAATAAGTTC ATGAACAGCCTGTGAAACATATCATGACCCATCTCTACAAAAAATAAAAATAAATTAGCT AGGCATAAATACTGATGCAAGCCTGTAGTCTTAGCTACTCAGGAGACTCAGGTGGGAGGA TCACTTGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTGTGATTGTGGCACTGAACTCCAGC CTAAGTAACAGGCTTAACATTCTTATAAATTAAGGACCTCAAAGAAATTTTATATATGGG AATATATCTATTATCATATCTATTACCATATTATATCTATATCATATTATAAACTAACAA AAATTTTACAGTATTTGAAATTAAAACTGAGAATGTTACTATATTGAATAATAAAATAAA TATGTACATTAGAAAACATACAGTAATCATTTAAATACTTATTCATCTTTTAAAAAATAA AAAAGTAAACCTATTACGGGTTAACACAATTTTATTTTTAAAAACTGCATCTTTTAAAAC AAAAATAATGAGAAGAGAATATTGTTTTACATTTCTGCAAATCTCTTTAATGTCTGTCTT AACAGAAGACAGATGGGTTCTCATATTTGTTTCTGTATTCAATCTGTTGTGATAGCACAT ATTATGCAGTCTCTGGAAAACACTGTATAATCATGAGAAGCTGAGGGTCAATAAGGCAAA TAACATTTTGGTATTATTAGAAAAAGTGCTGACATTATGAATTCCCTTAAGAGGTCTTAC GGTCCATCCTACAGGAGATCCCAGAAGACACTGTGAAATCCAGTGAAATACCGTGACAAT TTTTCAAAGAAATGTAAGAGTCAACAACAAAGTATGGTGGTGAAAACCATGAGTTCTGGA ACTGATTTGCCTGGGTTCAAAACTCAGCTCCACCACTTTCTACCTGTGTTACCTTGGGCA AGTTCCTTAAATCTTTTTATGTCTCAGTTTCTTCATTTGTAAAATGAAAGCAATAATAGT ATTTATCTCATGTATTTCTTGAAATATTGGGATAATGAAATAAACTAATAATTGCAAAAG GCACAGACCAGCATCTGGTAGAAAATAAGCACATATAAATGTTACTAAAGAATAGGAGAT AGGTGGGTATAAGTAGATAGAATGATAGGCAGAGTGCATTAAGTTGGCAAGTGTACTTCA GTCCACTTAATTTGTGATTTCTTTTTAAAAAAAAAACAAGTATTTTTCTGATTATGAGAT AAATGCTATGAAAATTCTGCACAATGTACTTACATCAATAACATCCTTTTGTCTATCAAG CAATTCCTAAACAGAGGAAGGAGACTGAGTTTGAGTTCCTCATTAAAAAATTAAAAAATA ATGCCTCAATTAAAAGAATTCAAGGATTTATCATATAATTCATTATGAAATCATGAAACT ATAAAAGAACCTGAGAATGTATATAAACTATATACATATATGCCTTACTCTCAGGAGGCC TACAAGCAATTTCTTTTTTTTCTTGACAACAAAGTAAACACAATTATTTTTACGTTTTTT AACATTTTCTTAAGTATTTAATATATTAGTTACAGTTTCTTGCATGGTGTTTGTAAAAAA AAAAATTTTGCTGTGTTTTTTCTGGCTTTCAAAAACAAAATAAAGCAGAAACAGAATATT AACTCTGGCCACCTGGGAGCATGGCAATACTACATGGAGAAGGAAACAAAAAGGAAATCA ATGAAACCTATTCCCAATATAGGATCCCAGTTCAAACACCAAGAGACTTAAAGTAAGTAA TACCTGAAAATTTGTCCATGTCCTTGAAAGGCAAGCTATACACAAGTTGTTGGTCATTCT GTTGTAATAAAGTAGCTCCAGGTATATGTTGTTTAACCAGTGAAGAAAGAGATTCTGTGG CACAATATTTGTCTATGTACATGCTAGAGAATACCAAAAATCACAATTAATGATTATACA ATAAACAGCCAAAAGTAAATTATGAAGGCTTTAAATTAAATTTAGTACCATAAATGATGG TCAAAGCATATAACAGCAAGCCTCCAACATAATAACAGTATAGCAAGAGTATAATATAGA ATAATGTCAATAAAAATGAATGATACCTCAGGCGGTAGCCGATCCCCCATTTACTTTTGA GGAACATTGAAGAACCAACACATTTCAGCATTCCTTGTGATATCACAGCTTTCCTATCTG CAGATAAATATTTACATTTCAATTTCTAAAGTATCAACAGCATTAATAATTGGCATTTAC ATTTTATGGTTTCTCATATGAGAGTCATCCACATTATGATATCATTAATCATCACAAAAA GTCTTATGAGGATGGTACTAGATTATCATCAACTATTTTTCAGATATGAATACTAAGGTA AAAAGAAAATACATTCCTTATATATGTTTCATACAGCTATTAAGTAACAAAGCCAGGAAC TCTACTCAAGGAGTCTGACTCTAGAGTCTACTTACCATATGTTATTCCAAATATATTTTT CCTAAAAGGCTTACCAATACAAGCACTTTCACAATTTCCTTTATAACCAAATGTAGAAAC AACTCCAAAAATCAACAAAAGTAATAAGAAGAACAAATGTTAGTTTGTTGGGTTTTTAAA AATAAAGGTACTACTGAAGACATGAATGACTTGCCCAATTTTATTAGATTATATTATAAG CAGACAGAAGTTGCTCAAGAATTTCAAACTTCTATATCTGTCATAGCTATTAAAAGTCAT GTGTTGACTTCAACTTGGATTCTTTATATGTATGTATGTGTATAAAATTGTGCAGAAAAG AGTTAACATAGCAGGTCAGAGGCTTCTATCCTTAGAAAGGCCTGCTTACAAGGTTGGCCC TTGGCTGTTAGTTGAGAACTTGGATTTGGGAGGGTTCCTACTATTCTCAAAACAGGTAAG AGTGGCTCAGTGCCTAAACTGTACAAACAATGTGGTTTATGCCAAACAACTTCTTTCCTT CTGAGAATCTGGAACTTTGGTATGTGCTAGGCAGAAGATGTTTATGTGATCAGCACCCAA TAAGAATCTTGAACACTGAGTATATACTAACTTTCCCAAGTAGATATTTCACACATGTTG TTACAACTCAATGCTGAAGAAATTAAAGCACATCTGTCTACTCCACTGGGAGTAGGACTC TTGGAAGCTTCTACCTGGTTTCCTCGAGACTTTGCCTCATATACCTTTTCCCTTTGCTAA CTTAGCTTTGTATCCTTTTGCTGTAATAAATCATAGTCATGAGTATGACTATGTGCTGAG TCATATGAGTTCTTCTAGGACATCACTAAACCTGGGATGGTCTTGGAGATTCTCAACACA AAAATGTATCATTTTAAAATTTTTTAGAACTTTTTTTGTGAAGGAAACATACCACTAGGT AAAAGCTTCTCTATTTATACCTCAGGAATTAGCATCTCTATATCCATCTTCCTTTTGGCC CATGATCTCAGCCTTCGAAAATAAAACAAAAATCTCACCTGCAAGAATGTCAGCTTCATC CATGAAATGAGTACTGAACACTGTCACCCGATTGGCTTTTCTGTATTTTAAAAGATTCCA TACAATATGTCGAGAACAGGGGTCCATTCCAGCTGTTGGTTCATCTAGCAGCAGTATCTG TGTGAAAAGAGGTGAAGAAGGGCAGGGAATCCTCAGAAAAACTAAATATTAAACAGGCAT GTGGACACTAAAAAACTGCCCCATTTCAAATTATTATTTTCAATCAGAAATATATTAGAT CAGATTTTTTCATTCATAATTGAGTTCACATAAATTTTTAAAATTATAAATTTGACATGT GAATATTTTCCCAGGTTTAATTCTAAAAGACTGCCTGTAATACACAAGACAAAAGTATAA CAACAGTCAGACAAACAAACTAAAAACAAAACATTAAGTATATTGCTATTATCCTTAACA ATTAAATTTGTAGATGTAACACTTGCTTTTTTGGAGAAGAATATATGGTTTTATAGTAGT TCAAGGGAAGCAATTTGTTTCAAGACTATTTTTAATATAAAAAAGAACATGGTGGTGGTG GCTGAGAGGAAGACTAATGAACATAAAGCCAGGATCCAGAATCATTCCCCAGCTGCAACA GCAAGGGGGAATGTGGCAGGATGGTGGGGATCAATAGGAGATCATCCTAGCTGCATGCAT GCACCTGTCAGTTTTGATGCCCTGTGTAAAGTGGTACATCAGTTGTTTCTCTGTTTCTAT GACAGAGAACAGCATAAAACAAATACATACAAAATCAAAGCAGGACAGTGATAAACTGAA TCACTCCTTTGATTTTGTTCTATTTCTTAACTTTTGTTATTAACTATAACAAATATTTTT TAAACTATAGAGAACAAGAGAGTAATACTATTATAGCTACCATTCCAATTCAGCAATGTT ATTTTTTGGCCACATTTTCTTCAGATCATTTTTTAAAGAAATAAAACATGGAGGCCAGGC GTGGTGGCTCATGCCTGTAATCCCAACACTTTGGAAGGCAAAGGCGGGAGGATCGCTTGA GGCCAGTTCAAGACCAGCCTGGGCAACATAGCAAGGTCTCGTCTCTACAAATTAAAAAAA AAAAGAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAACATGGCAGTCATAACTAAAG TCTATTCTTCCATTCTCCTTCCTAAAAGTAACCAGTTATCATAAAGATGTTATAACTCAG AAAGGAAAGGGTGGAAGGGGGTGAGGAATAAAAAAAACTACATATTGAGTACCATGTACA GTACTCAGGAGATGGGTGCACTAAAACCTCAGAATTTACCACTATATAATTCATCCATGT AACCAAAAACCTTTAGTACCTTGACAGCTACTAAAATTAAAAAAAGTTATACATCTTTCT GACTTCACTTTTAAAATCTCATTACTATGATTATATCCATAATAACATACAGCATTTTAT GTACACTTAACCTTTACATAATGTATTATATCTTTCTACAACCTGCTTTTTAATTCGACA TAATTTAAAATGAGCTCATCTGTAAAAGTAATATTTATTTACCTTTGGGTTCCCAAGAAC AGCAATTCCTAATGACAGCTTTCTTTTTTGACCACCACTTAATTTTTTAGCTTGGTTATC TTTGATAGTCTGCATGTCTAAATCTAGTAAAACCTTCTGCACCTGTAAAAGTAAAGCATG AACAATGTTATTTTAAAAATCATACCATTTATATAATTATCAATATTACTTTTTAAATAT TTTAAGTTTTAATGTGTTAGATATTTAAGTAACATAGGTTTTTAAATAATTTTAATATCA ACTTTAAAAATGATCCTTTAGCATGGAACTGCCTTTGACATATACTCATATATAATTATG AAAACAACAGGTAACAAGATTCTTGAGGGAAAGGTTTTAATTTTGTGCCTTCTTGGGTGG TAGGGAAGGAATAAGAGATCACTGTGATGGCTCTTAATGTATGTGTGGAAGTGGGAGGGG GTAGAGGAGATGAGAGCAAGAGAAGGCAGGAATAAGGCAGGCAAGCATCCTCCAGATGAA ACAAACTTTTATGTGTGCTAAAACATTTACTCCAAATTCTGTCTAATTCTTTGTAATAGC TTTCTGTTTGCTGGCTCAGAACAAGTGTTATATTTAGATTTTCAAGCATATTTTTATTGC ACAAGTCATTACAAAAGGTTATTGATTACAGGAAATAAAAGTAAAGATTTCTATATGAAT AGCATACTTCTTGTATTATATTGTTGGCTGGTATCCCTTTGATTGAAGCCAAAATTGATA AATTTTCTTCTACTGTCAAAACATCAAAGTGTATATCTAACTGTGGACAAATGCCAATCA TTTTTCTTGCTTCAAACATTTCATCTATTTCTGAGACTCTGTGTCCATATATAGATGCAA ACCCTAAAAGCAAAATATATATTTAAATGTACATTAATTATTTTATAATGTGTATGTTTT CAAGTATCCTGATAACTTAGTTATTTGGTTATAACAGACATATAAGGTAAAAATTAATAT AAATTTACAAGGCACAACACACCCTTCAATATTATTGGTGATCCGCATCCACTTATATTT CAATCTCATTTTCCATCACTTACAGGTCATATAACATAGTGGGAAAAGCAAGAAAGTAAA AGCTTGACACTAAACATAAATATCTATTGATACACTATTTACACTTGTATTCCAGTAACA ATTTTCTAGACACTGTGCAATAGTGGAGGGATTAAAGAACTATAAATTTTATCCTAACTA GCTGTGTGGTCATGGCCAAATTACTTAATCTCTTTAAATTCCAGCTTTCCTTTTTTATAC AGTGAACACTAATATATTCATTGTTTTAATAGTGAAAATTAAAACAATCATACATTATGA AGAATCATGAGGAAAAATCATAAATTCTTATACAAATGTAAGATATTATGACTACCATCA AAGAGTGATACAACTAAGGACAAAGAACAAAATCAAACTAATTTTAAAAGTTAAATAACA TTTAAAGAGTTGAAATGCAGATTCAATACAATTCAGCCCTTTTGTAAAGTAAAATATTTA TTGTACTGCCACTCTATTTGGTTACTGTCATAATATGGAGCTACTATAATGAATTCTCAC CTACCAAACAATCACATATCAAAATTATACTTTTGAGGTATGCCTTTAAAATTCTATTTT AGAAGATAGTATGAACATTTACAATTATTTCCTGCTGAACTATTGCTGTATATTTAGATA TTTGTGTTTATTTTCTCAACCTCAAATAGTCTATAGTTCTGATTTAATTTCCAATAAGTT ACTCATTTATCCTCCCTTGAAAATGATGAATAAAAACACATACATACACATCTACGTGTG TATATGTATAGAAATATGTACAAAATTAGATCCTTTTTACTTTATTAAACATGATAGAAT CATTTTTATCTTCTACTAAAAACAACCACATGTGTATAATCAAGAAAAAAAGAAAACACC TTTACAGATACAGAAGTTGGTCCCATTGACAAAAATTATTCAATACACATTTAAAGAATA TATATAATGAAGTTTTTTTTTCTTTAAGACAGAAAACTCACCATCAGAAGGTGGGCAGAG TCCACAAAGAATATTCATCAATGTACTCTTTCCTGTTCCACTGTGGCCAAGTAAGGCAGT AATCTGACCCTCATATATGTCAAATGACAAATCTAGTTCAGGAAAAAAGAAGACTCAAAT GTAATTTTTATGTCTGTTCAGCTATGCATGATAATTCATAATATTTGAGCAATCTTCAAG GCACTATATCTATAAATACATATTTAAAGTTACCAGCATATTTGATAGCAGGTAAAACAG CTTCTTTGTTACAGTCAACGATATAAACAGTAATGAAAGTAAATAAAAATAAACTTTATT TGTTCATACAGTAAGATTTAAGAGTATACAAAATATTTGGGAATTTTCTGTGTCCCAATT TTTGGGAATTACCAATGGAACCAATGGAATTAAACAAAAATTTGTTCCCAAGGATATTTA TAGGCATTTAAATAAACTGGCAAAAAAACAAGAAATTAACCAATAGCATAGAAATGGCTT GAAAGGTTAGATTTAATGAAGCAATATCACTGAATGGATATGTAAAGGAATGAAGGAAGA CAGGAGATGGGGACCTGAAATGATGAAGCAGAAATGGCTTATCAAAAAACTAGGCTGGCC AGGCACAGTGGCTCGTGCCTGTAATCCCAACACTTTGGGAGGCTGAGGTGGGAGGATCAC TTGGGCCCAGGAGTTCGAGACTAGCCTGGGCAACATGGCGAAATCCCGTCTCTACAAAAA ATATAAAAATTAGCTGGGCATGGTGGCACCTGTAGTCCCAGCTACTCGGAAGGCTGAGGT GGGAGAATCACCTGAGCTTGGGAAGTCAGGGCTATGATAAGCCAAGACTGTGCCACTGTC CTCCAGCCTGGGGGACAGAGCAAGACCCTGTCTCAAAAACAAACAAACAACAACAAAAAC TAGACTAAGAAGGCTAACATATAAAACAAGAAGGAAAAAGTCTCAGATCCTAACGCCAAT AATCTAAGTTAAAATAAGAAAGGGAACTCAACAACTAAACGTTAAGTGTTCTGCCCCATG AACGTGGTATTTCTATTTATTTAAATCTTCTTTAATTTCTCTCAGCAATGTTTTGGACTT ATCAGGATATGTCTTTTACATTTTTGTCTTATTTACCTGTAAGCATATTTTTTGATGCTA AATGCTATTTTTAATTTTAATTTCCAATTATGTGTTGGTAACATATAGAAATACAATTGA TTTTTCCATTATTTATCATGTATCCTATCATCTTGCAAAACTCACTGTTTAGTTCCACTA TTATTTTTTGTCAATCTAAAAGATTTTAAAAATAGATTATTGTGTCAACTGCAAATAATT TTACTGCATCCTTTCCAATCTGGATGCCTTTTATTTCATTCTCTTGCTTCTTTGCATTAG AAACAATTAGTTGTAATTGTTATTACAATTATAATTATACTTAACTAGTTGTACCAATAA CTTACATTGGAGGTTATATATAATCTCCAATGTTGAATAAAAAGACGTGAAAAGCACTGT AACCATAAAAGAACAGATTCATAAATTGGACTTCATTCAAATTAAGACTTGTGTTTGTCA AAAGACACTGCTAGTAGAATTAAAAGGCAAGCCTCAGACTGAGATCAAATATTTAAATAC CTGTATCTAACAAAGGTCTTGAAACAAAAATGTGAAAAGAACTTGAATAGGCATTTCATA AAGGAAAACCTCCAAATGCCAATAATCATATAAAAAGGTGATTAATAACATTAGTTATTA GGCAAATGCAAACTAAAACCCTATTAGTATACCACTATACCTACTTTCTTCTTAATAAAT TAATTTGCCTCCTAGAAGACATTTGGTAAAGACTGGAGACATTTTTGGTTGTTACAACTG GGAGAGGATGTTTAGCAGTGTGCCAGGGATGTTTAGCAGCGTGTCAGTCAGTCTCCAGAA CCAACAGAATACACACACACACACACACAATGGAGCAAGTATGAGTGTGGGGTTGGGGGA TTAGGGAAGGTTTATTTTAAGAAATTGCTTCAGAAGATTGTGGGGTCTAGTAAGTCCCAA AAATCTGTAGGGCAGGTTGAAAACTCAGGCAAGAGTTAAAGTTGCCATCTTGGGTCCAAA ATTCATAGGCTGACAGGCTGGAAACTCACGCAAGAATCTGTTTCATTCTTGAGGCAGAAC TCCTTCTCTCTTTGGTGATCAAAGCCAGGGATGCTGCTTGTGAAGGTTAATTTTATGGGT CCCCCTGGCTAGGCTATGGTGCCGTTATTTGGTCAAATACTGATGTAGAAGTTGCTGTAG ATGTCATTAACTTTTATAATCATCTGAGTTAAACTTGATTAGTCTTGATAATAATGGTAA ACCTTATCCAATCAGTTGAAGGCCTTAAGAGAAAAAACAGGTTCCTTGGAAGAGTCCTGC CTCAAGAATGTAACAGACTCCTACATGAGTGTGCAGCCTGTCAGCCTGTCTACAAATTTT GAGCTCAAGACTGAAACTTCAACACTTGCCTGAGTTTCCAACCTGCCTTACAGATTTCTA CATTTACCAGGGCCCACTATCTCATGAAGTAATTACTTAAAACAAACCTCCCCTAATCCC CCACCCTACAATCATACTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCG TGTGTGTGTGTTTGTGTGTGTGTGTATTCTATTGGTTCTGGGGACTGACTAACACATTGA CACAATGCTAAACATTCTACATTAAAGAACAGTTCTTCACAACAAAGAATTATCAGGACC AAAATGTCAGTAGTGCTGAGGTTGAAAAACCCTACGATAGGCCAAATGAATTTTTCAAAA AGTAACTAACATGTATTGCATATACATGCAAAATAATAAACTGAAACAAGGACATAGCCT TATTCAAATAATTGAGTATTTTTCATTTTAATAGATACTACATTTTACTTTTACAAATGT CATGTTGTTAGTTTTATTTTGAATATTAATCACATAAACGAAAGTATCTCAAAAAAGCAA GACAGGGGCTGGGCGCAGTGGCTCATGCCTGTAATTCCAGCACTTTAGGAGGCTGAGGCG GGCGAACCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACTTGGTGAAACCCCGTC TCCACAAAAATACAAAAATTAGCTGGGCATGGTGGCGTACACCTGTAATCCCACCTACTC AGGAGGCTAAGGCAGGCGAATCACTTGAACCCAGAAGGCGCAGGTTGCAGTGAGCCAAGA GAACGCCACTGCACTATAACCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAATAAAA TAAAATAAAAGCAAGACAGAAAATCATGGTAGAGAAGTTTAAATTTCCCACAAGCTATGC AAATTATTTTTCTAGTTGTACTTTAAATACTATGGCCTGAATACTAGGAAAACTACTTAC TTCTCAAAGCCTCCACATTTTCACCCTTCTTTCTGTATGTCTTCTGAATACCACTAATTC TGAAATATAAAGTTTTATATTTTAAGTATTTAAAGCAATTTATAAGTATGTGTGTTTATT TACCATGCATATTTTTATCAATGCTATCACATTTTATAAGAATAATAAAATAATAATAAA GTACTTTCCTACTAAAACAATGAACCAAATAATGTTGATAATGAAAATACAATTGACACT TGAAAACACAGGTTAGGAGTGCCAACTGCCACACATAGTTGAAAATACACATATAACATT TTTAATCCCCTAAAACTAATCTATTAATAGCCTACTATTGATAAGAAGTCTTGCAGATAA CATAAACCGTTGTTTAGCATATATTTTGTAGGTTTTACATGTTAAACACTGTATTTTTAT GAAGTACACTAAAGAAAATGTTAAGAAATTATAAGGAAAAAATATATATTTACATTATTA TACTGTATTTATCAATGCCGTCAGTTCACATCATCTATTTATAAGATGAACAAGATGCAC AGTCTATCTGAAATGACAGGTAACCGCACCCACAGACCTCAATCTATGGTACATACAAGC AATTCAACTTTTTCTTATAATGTCATGACCTTTCTCTGCTTCTTGAGAGCACTTCCAGCA TCACTAGTGGCAATTCCTATGGATCCCATGATGCTATTCAAGGCTTACGGTATTGCACTA CACATAATAAAAAATAAGCAAGAACCCTGAGACATTACTTTTTATCATGATATGCAATTT ACTGGAGAGATGAACAGCTCACAAGGAGATAATTGAGTCACATGGCATTCGAAGTATATG CTTGGAACACACAAGCTCACCATAACAGCAAAAGAAGGTGCTACAAAATTATTGCAGTGG TACAGTAATACTGTAGTTAATATTATGCAGCTATGATTTAATACTGCATCTTCACATTTG TTTACATTTCTCTCAACTGGGCATTGGCATAATGTAGGTCTGTCAATATTGTGTACATTA AGCTTTGATAAAGCATAACTTACTATAATCTGTGTATATTTTATGGTAGCAAATGTTAAA ATAGACTAATATCTATAAATATTTTATGCATTCATGACATACCTAACATTTGTTTTTGGT ATTTCTAGGCTAACAGTTCATCTGCGAGTTTTTTCAAATTGTTACAAATCTCCAAAAAAA TTTTCAATATATTTACTGAAAAAAATCCACATATAAGTGAACTGGTGTAGTTCAAACTTG TATTTTTCAGGGATCAACTATAAAATTATTTTAAAGAAGGTACAAGAGAAAAGCATAGTA TTCCTTTCCATTGTAAGCGTCATTGATTCATTTTTCATGCCAACCCAACTTCTAAAACTA AGTGAAGAATCTGATTTAAGCAATTTATGGATTTTTTTTCATTTCTGATTATCAAACACT TGTTACATCAGTGAAGGGGGATATAAACCAGATGTCATTTCATGTCAGCACAAATTTCAA ACCATTAACAAATGTGAAGTGATTTTCTTATTCTACCTTATTTTTTTCATATTTTTTTAA GGAAATGATTTGTTAATCAGTTAAAATTTACCGTTAAGAAAGCAGGCCACTGGCCAATGA ATTACATCTTAAGTATTTTGACTTTCTCTGGAATTTTTACATTTTTCTTAAATTTAAAAA ATATTATGCTTCACTTTTTTATTTCATTTTATTTTATTTCTTTTCTTTCACCTAATTTTA TTTCTAAATTTGGTACTGACTGACCTAACAAGGAATCGTAATGAATTTCTTTGGTTCTTA AAAATTAAAGTAATGAAATGTTCTAATTATGCCTCAAACCCTAAAAATCTATGAAATTAA CAGATGACAATTTAATATGCTGTATAAAACAATGTAGCATGAACAAAATTATATAGTTAA TATTTATCATGTTTCAGTCTACATAATGGGAAAAGCTTTAAACATTAATTGTATAAACAT CAGGTTTTATTACTTTTAAAATTTTCCATCCAAACATAAAATTTCAGGGGACAGGTGTGG TGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGCT ACGAATTCGAGACCAGTCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAA ATTAGCCAGGCATGGTGGCGCATGCCTGTAGACTCAACTACTTGAGAGGTTGAGGCACAA GAATTGTTTGAATCTGGGAGGTGGAGGTTACAGTGAGCCGAGATTGTGCCACTGTGCTCC AGGCTGGGCGACAGAGCGAGATTCTGTCTCAAAAAACAGAAAGAAAGAAACATAAAATTT CAAACCTAGCACCAACTTTATTCTAAATGGTTGCAAAGAAAATAAGAAAAAGAGAAAAGT AGCCCTTATTAATGTTTTAAAATCATGGCATATGTACCAAATCTAATATACCATATTTAC ATACATATTTAAAGAATAGGATTTAAATGTTTCATCAGCAGTTCTTATACCTAAATTGCC AAAGATTGAACCATACCTTATGGCTTCTTTTCCTACAAATTCTGAAGAAACTGGCTCAAT AATTTCACTAAAACTAATATTTCCATTAACATTGCCCTCTGATAACTCCTCATAATTTCT TTTGCTCTTTGACCAATATGAAGGCTTCAGAAAATATAAAGATGATCTCCGTAAGCCAAA TTCCCCTGAAAAATAAACATTAAAAAACTGAGTTACCATAATTAGTTTTTAAATCATAAA GACAGCATTTCAAACATATGACAACCTGCATCTAAAGTTTAGGTACCATTCCGCAACATA TATATATTTCCAAACATCATGTTGTACACAATAAATATATACAATTTTCATTTGTCATTG AAAAGTAATAAGTAAATAAAGATTAGCTGTATTGTATTAAATCAATATTGTATGAATCAA AGTTTTATTGATAAATAATTCTAGTCCATAAATAGTTTCAGAATTGCTGAGTGGGAGGTA AAGGTGAATAAAGCACATCTTCTATGCTAAAGGAACTAATGCCTTTATGAGTACAAGTAG ATAGCAAATGGCAAGAACACAACACAGGCTGAATGTGTTGAAGACTTGAATGGGCACCAT CTTAAATGATCTTTGAAAATAGGTAGTAACTAGAAAAGTGGATATGCTTCATGGAAAAGA CTACAGAATTATGGAGAGCAACAAAACAACAGGATAGAAATATGAGACTTAGAAATGGTA TACAATGAGGCCAGGCATGGTGGCTCTCACCTATAATCCCAACACTTTGGAAGGCAGAGG CTGGCATATTGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAATATGGCAAAACCTTG TCTCTGCAAAAAATACAAAAAATTAGTCAGATGCGGTGGTGCATGCCTGTAGTCCCAGCT ACCTGGGAGGCTGAGGCAAGGGGATCACTTGAGCCCAGGAGGCTGAGCCTGCAGTGAGCT GTGATCGTGCCACTGCACTCCAGCTTGGAAGACACAGCAAAACCCTGTCTCAAAAAAGAC ACAGCAAAACCCTGTCGGAAGGAAGGAAGGTAGGTAGGAAGGAAGGAAGGAAGGAAGGAA GGAAGGAAGGAAGGAAGGAAGGAAGGAAGGGAGGGAGGGGAAAGAGAAAGAAAGAGAGAG AGAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAAGAAGGAAAGAAAGGGCATACAGTG GTAACTGCCCAGACAACATGTTCCATTTTCTCCCTTTTCCCTCTCAAAATACCTACACTC CTCATTTTTTTCAAATATCTACTCTTCTTTTAGATTGGCCACATTTCAAAGGGATCTGAT GCCAAGTACAGAGGATTCCAATTGATTTTATCAGTACTTGGCATTCCTCTGGGAACTGTT ACTGCTCCAACAGCAAGCAAACAAAAACATAAATGTAGGGAAAGGACACCCTATTTAACA AATGGTGCTGGGATAATTGGCAAGCCACACGTAGAAGAATGAAACTGGATCCTCATCTCT CACCCTATACAAAAATCAACTCAAGATAGATAAAAGACTTAAATCTAAGACCTGAAACCA TAAAAATTTGAGACGATAACATCAGAAAAAAGGCAAAGACTTCATGACCAAGAAGCCAAA AGCAAATGCAACAAAAACAAAGATAGATAGGACTTAATTAAACCAAAAAGCTTCTCCATA GCAAAAGAAATAATCAGCAGTTGACAGATAACCCACAGAGTGGGAGAAGGTCTTCACTAT ATATATATGTTGACAAAGGACTAACATCTAGAATCTATGAGTCACTCAAATCAGCAAGAA CAAAACGAACAATCCCATCAAAAAGTACGCTAAGAACATGAATAGATAACTCTAATAAGA TATACAAATGGCCAAGAAACATGAAAAAATGCTCAACATCACTAATGATCAGGGAAATTC AGATCAAAACCACAATGTGATACCACCTTACTCCTACGAGAATGGCCATTATCGAAACAT CAAAAAATAATAGATGTTGGCATGGATGTGGTGAAAAGGGAACACTTTTCCACTGTTGGT GGGAATGTAAACTAGTAAAGCCACTATGGAAAGCAGTGTGGAGATTCCTTAAAGAACTAA GGTAAGTCTACCGATTGATCCAGCAATCCCACTCCTGGGCATCTACCCAGAGGAAAAGAA GTCATTATGTGAAAAATATACTTCCCCACACATGTTGATAACAGTATAATTAATTCACAA TTACAAAAATATGGAACCAACCTAAATGCCCATCCCAACAACTGGATAAAGAAAATGTGA TACACACACACACACATACACACACACACACACACACACACACACAAAGGAATCCTACTC ATCCATAAAAAGGAACAAAATAATGCCATTTGCAGCAACCTGGATGGAAATGGAGACCAT TATTCTAAGTAAAGTAACTCAGGAATAGAAAACCAAATATTGTATGTTCTCACTCATAAG TGGGAGCTAAGCTATGAGGACACAAAGACATAAGAACGATACAATGGATTATGGGGGCTC AGGGAAAAGGTGGGAGGGGGGTGAGGGATAAAAGAATACACACTGGGTACAGTGTACATT GCTAGGGTGACAGGTGCACCAATATCTCAGAAATTAACACTAAAGGACTTATTCATGTAA CCAAACACCACCTGTTCCCCAAAAATCTATTAAAAAATAATAAAACCTCAAAAAAAGGGG TGAAGTGCTCAGACAGACTTGAGGTATGTAACTAGATGAGAGATACTGCAATGGTCTAGA CTAGTGGTCCCCAGCCTTTTTGGCACCAGGGACTGGTTTTGTGATAGAAAATTTTTCCAC AGACAGGGAGCAAGGATAGTTTCAGGATGATTCAAATGCATTACATTTATTGTGAATTTT ATTTCTATTATTATTACATTGTAATATATAATGAAACAATTATACAACTCACTATAAGGT AGAATCAGTGGGAGCCCTGAGCTTGTTTTTCTGCAACTAGGCGGTCCCATCTGGGGGTGA TGGGAGACAGTGACAGATCATCAGGCATTAGATTCTCATAAGAAGCATGCAACCTAGATC CTTCACATGCGCGGTTCGCAATAGGGTTCATACTCCTATGAGAATTGAATGCTGCCACTG ATCTGACAGGAGGTGGAGCTCAGGTGGTAATGCAAGCAATGAGGAGCAGCTGTGAATACA GATGAAGCTTCACTCACATGCCTCCTACTGTGCAGCCCAGTTCCTCACAGGCAGCTAGTA AGATCTGTGTCCTGGGGGTTGGGAACCTCTAGTCTAGACTAGTATTACACAATACAACTT TTATAATGGTCAAAATGTTCTACAGAACATCTAGATTGCACCATGCAATTTAGTAACTAA CAGCCATATATGGCTACTGAGCACTTGGAATGTGGCCTGTGCTACTGAAAAAAATAAATT GTTAATTGATTTAATTGTAATCAATTTAAATTTTAAAAGCCACACATGGCTAGTAGTTAC CATACAGGACAGTACAGGTGTAGAATACAGACACAGGTAATGAGGAATACAAGTGGAAAA GGAAATATGCTCAATACTTAATATTACTATTGAATCTACAGGAGTTTGCTATATTGGCTA TAGATGTGGACAGGAGATAAAGAAAATGGTAGGAGTTACAAGATCACTTCATAGTTTTAG ACCTTAGAGGGTAAAATAAAATACTTCAATTAAAAAAGACTGATATAAAGAAGGACCAAG GTAAGATCAACTAGAGACTTAAGGCTTTCAAAACTGCTCTCTTTTTACACGATCTCTTTA TGTTCACTAGTGGCTATAGCCTAAGGTACAAAATATACTTATTTAAAGTCAAATTAAAAG CTTTAACAATGAATATGACTTAGGGTACCCTGGTTAGGAAAAAAAATCTTAAAATTAAGC TGACCCTATGTGGGCAAAAAAGCCTAAAAATCTTTAAAGTAAAATTCAAAAACCATCTGC ATACCTGGAATGACTTGATCAAGATAGACAGCCAAGAGGACATAGAATATACTATTAAGT GTGAGCATGATAATTGTAATAATTAGAGGATATGGGCCTGCAGTCAAATTTGAAAATGAA GCACCTTCATTAAAATCTTCTAAATGCATGACCTGAAAAATACAAACACTAACTTTATTA CATAAAAATGACAAAAACAAGCAAAAGCTAACACTACTTAAGAGTTATTTAGCATATCCA GAGTGATAGTAACCAACTGGGCCTTTTAATAGATTAAACACTTGACCAAATTAATAATAT AAATTTATAAGGAAAACAATAAAGACTTTACAAAAATGTAAGTTTATCAAACCAATTCCT TTCAATCATGTTTTTAATGTTGTGCTTCTTTAACTGGGATATATTCACTCTAGGGGCATT TAATTCCAATGTAATTACTAACAAATGAAATAAAAACAAACTGCAATATTAATAATAACA AATGCAAACAAAAGGGTTATGATCCATATGAAAGCCAAACAAATTAAGTATTAGGGAATA AAATTAGGTTAGCATCTTTCCAATAGAGAAAAGCAAGTATTTTGATTAATTAACACAATT ATTAAAGTATTCATAGTAGATATTTGTGATAGCATGGAAAGAGAAATGTACTGGAGGTTG AAGCCTCATTTAGGTCCTAGCCCTGCCATTAAGTGAATACGCTTTAATTATACTATTCTA GGCTTCAGTCCTCTCATTTATAAAATGAAGAAGATAAATTCAATGACACTGAAAGGCCAT CCCACTCACAACAAAAACCTATGAATCTATAATTCTTCGTTCCTAGAGAACGCGGACTCG GGGACTCAATGAACTCTCAAAATGTATAACAATCATTCTCAGGTCTCAAAAAAGTAAAAT GATTAACTCAATATTTAATTATATCTCATAAATCAGAACTTCTATCCAACCAACATGAGT AATTTCTTATATTTAGTAATTACATTTTTTTCTTTGTACATTAGCCAAATTCATGTTCCA CTACAAAGCCATTTCTTATAAGACTTCTTCCATTTAGAACCTAACTACTCCTGTAAGGAC TAATAAAAATAATATTTGTAAGTCTGAATGTTATTTTGAATGACAATTCCATGAAGCCTG GGCCAACAAAATCCACCAGGCCTACTTATTCCACCACTACACTCACGGTAAATTTGTTCT GCTCCACACACAATTTTCTCCCATGCATTCTTCTGAGATAAATGTACAAATGATAGCAAT ATAACCAGGCCATAGGCAATAAGAATTACTTGACATTTAAACACATTACTATCAAACTGA GTTTCTGCAGTGAAATAAATCACTGAGATACACTGAAGTAAAAAGTAAAAAATTTATAAA CAGAACATTTAACTAAAAACTTAAAATTGGACAAACATAAATAAAACTAGATATAAAATA TACTCTAGAAATCATTTCTTCCTCATGCTAAAATTTTAAAATAATTTTTTTGGTAAATCA AAGGTAGTATTCATGGTAGTATAAGAAGCTACATAAAACAGAAAGAAAATATTTAGTGAA TGCAAGATTAATATATTACCTACCTGTGCAATACCAATCACAAAAGTACAGTGACAGAAA GGACTGAAAAGCCACACTAACGATTTGGGAAAACTTTCTATGAGGATTATCATAAGGCCA ATAAATCCAAAAGCCACAGTAACAAAAAATTCAACTATTCCCACATGTTTTGATTTTTTA AAAAGAGGTGTCAGCATTAAAGCAAAAAATACCTATAAAATACAAATATTAAGGTTAGTG CAATGTTCATATATACCAGTATGAAAACAAAATTAAAGTTTGCTTCTGAAAGAACAAGCT ATTTTCATGAAAAATGCATTCATAAAAATACAACTATAATTTCTAAATGCTATGGTATTT TATTTTCAAACAAATAGTGATATACCTTTTAAAAATTTAAACTAACAAATATTTTTGTGT TTTTGTTTTGATTTTGTTTTTGAGACAGGGTCTTGTTCTGTCACCCTAGCTGAAGTGCAG TGGTGCCATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAGGTGATCCTCCCACCTC AGCCTCCCGTGTAGCTGGGATTACAGGCGTGGGGCACCACGTCCAGCATTTTAGTATTTT TTTTGTAGAGACAGGGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTTGCCTCAAG CAATCTTCTTGCCTTGCCTCCCAAAGTGCTGGGATTACGGGTGTGAGCCACCACATCTGG TCTTAAACTAACAAATATTAAATACTGTATTTTTATCTGTATCATAGGTAAACATGACCA CCTCTACATTACAGAAACCATAAATAGCCATGTGTTTCTGCAGTAAGATGCATAAAATAT GTGAAAAAATAATAAATCAACAAAAATTTTAAGTACAAGACCCATATTTTAAACTTAATT TATTCATAAGATAAAAAAAACAGTTTAAAAAGAAAAAAAAAACCAGAAGGCCTGCTGCAG TGGCTCGCTCATGTAATCCCAGCACTTTGGGAGGCCAAGGCAAGTGGATCACTTGAGCCC AGGAGTTCAAGACCAAACTTGGACACTTAGGAAGACCTCGACTCTAAAAAAAAAAAAAAA AAAAAAAAAAAATATATATATATATATATATATACATACATATATATATATGTATATATA TATATACATACATATATATATGTATATATATATATACATATATACATACACACACACAAA AATTAGCAAGGTGTGATGGCACACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTTGA AGGATTGAGCCTGGGAGGTCAAGGCTGCAGTGAGCCATGAGTGTGCCACTGCACTCCAGC CTGGGCCACAGAGCAAGACCCTGTCTCAAAAAAGTAAAATTAAACATTTAAAAAAAAACC AGGCAATTACATATGGAAGTATGTTAGTTATTTGCAATTTATTATTTTAAAGAGCAGAAA TGATAGCCAAAACATTTAACAACTGATACAGGGTGGGCACATAAACCAATCAGAATGGAA GATGGAACCACTTAAAACAAAGGCTGGTCATTAAAACCTCTCATTCAGCCAATATATCAA ATGAATATCAAGACTGCTAAAGAGTTACATTTGCAAAGATGTATCTTTAAAAATCATCAT CCTGGAGCATAAATTAACTTGAAAGAGTAAGGATTCCATGAAGACAAACAAAAATAGTCC AATACTTGACAGTCTTAATTATATACATCATTATATAAAGACAACAGATAGAGGAGTTGT ATGTGAAATACATCATATGACAAAAGCTAAATCTAAATCTAAAACTATTTTGTAACATTA CTAAAAATACAGGAATACAGTGATGCCACATCATTTATTTATTAAGTCACTTATCAATTA GTAAAATCTGTCTTTCATGGCAAATTGACTATAAGTAAACTGAAGAAAAAGACTTTGCTA TGTTATCAAACATTTTGACAGTTCTTTATTCCTATCACAAGTTAAAATACTTACAGATGA TAATCCATAAAGGAAAAAAAGCAGAAATATCACAATGCTGCTACTTTGAGGAAATAACAA AGAAGCTGTCGCAATGACTGCCATAAGAAGGGACATAAGAAAAATTAAACTTGTATATAG AAGAACCCAGGAAAGCCTAAAATGAGAATACAGATATAGTTATGGTCAAATGCATAGGCT TAACCAGTTAAAAAATCATTTTAAACAAAATTTTTAGATTTTAGCCATTTTATTCTTAAA ATTAAGTCACTGTTCATTTCTGTGTATGCTTATGTACTAAAAATTAATAGTCTTGTAAGT AATTAAAAATAGTATTGGTTAAGTGATAGGTAAAAGTGTAATCTGATAAAAAATACTATC TTCCAGAGTTAAAAAAGCTTTCAAAATGAATAGTAATTCATAATTAATTTAAATCTAATA TTCTCAAAAGTTCAATAGCACACAATGTCTCTGATTTTCTTAAAATGTAGGAGTTTAATG AGTCAAGATAACAATTTTCTTTATGGCATGTGCTACAATTAAACCTCTGATGGCTTCTGT AACTATAAACAATAAAGGCTACCTTACCTCACTAATCAATGACATAATTACTACAATTAC ACAATGTGAAATCAACAAGATCAGTAATGAATTCACTATTTTTGCTCAAGACTTCTTTAC AAATCAGAGCTCAATGGAATTGCTGCAGTATTAAGTTTTATTTTACATATTTTTCCAAGT TAGCTCAGGATTTAATGATGTCATGAAATCACTGAGTTAAGGCTAAAAAGGTAGCGAAAT TATCAAAATTGAATCCATCATTTTACTGAGGCAAAACTGAGACCCTGAGAGAATGATTTG CCTAAATTCTTCCAGCTACCGGTTCTCCATAAAATACTTTAATAACCCAATAAATTTTAA AAACCAATCCTTTGGCCAGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGC CAAGATGAGAGGATCACTTGAGGCCAAGACTTTGAGACCAGCCTGCACAACATGGCGAGA CCCCCGTCCCTACAAAAAAATTGAAAATTAGTTGGGCATGACAGCATGCACCTGTAGTCC CAACTACTTGAGAGACTGAGATGGGAGAATCTCTTGAGCCTGGGAGTTTGAGGCCACAGT GACCCATGATCATGCCACTATACTCCAGCCTAGGTGACAGAGCAAGACCCTGTCTCAAAA AATAATCCAAAACCAATAATTTCTAAAATAACAAATGAAAGAAAAACAAGCAAAGGAAAT ATGTTATATACAATAATTCCATTATGTAAAGTGTTAATGATTAATTGTTACATTGGGCTA ATTGGAATAAAATTTTGTAAAACAGACTATAACAGCTCACATGCACAGTATTAACCTTCC CCCCAGAATGAACTTCATTACATAGTGAAAAGAGTAAGGAAACTACACTTAGATTTATAA AAATGCATGCCTTTGTAAAATTATCACTGTACAAAAATGCTGATACATTAAAGGTCACTA GTGAAAACATGGTTTTCTCATTTCTTTCTCTAAAATTATTTCCATATTCATCTTAATTCA CCCAAATAACTAAAACTTTCGAGGGAAAAAAAGTCCATATACCACATATACAGACTTTAA TCACTATAACTAAATTTTTAATATTATATATATGCTATATTATGGAAGAACTGTAACAAG CAATTAATTTCTAATGTTCCAAGATTTCACATTTCCTGAACTCTGAAATACACAGAAATA TACGTGGAGTATATTGAAATACACTGAAATATACACGGAGTGTGCCCATGATTCAAATAA AATGTGAAATAAAATTTAAACACGTATTGTCAACACAAGCTTTGACATTCTTCATCCCTT ATGTTAAATGAAGCCAATTAGTTGTTGAAACTTCTTGACTAATCTCAAATTCCAAGACTA AGGCAATCATTGTAAGAAAACAGGATAAGCACATCATCAAGTTAGGTAAATATCAAAATT ACAATTTTGAAAATCTGTATATTTAATACAATTTTTAATTATATTAAGTAATAAATTTTT AATAACATACCAAAAGGCAGTATCATGAAGTCCCATTATCTTTAAAAATTCTTTTATTTT TTTTTCTTTTTCTGCTACGATATGAATTGCCAAAAAGTATCCAAAAGGTGAAAATGCTAT AACTAGGTATATTAAAATTACTCCTCGGGGAAAGGTATCTATTTCTACAACAGCAGTTTC TCCCATAATAACAGCTTTAGTTGACTCCAGCTCCTTCCAAAGAGAAACATTGGTCTTCAA CTATAATTAGAAAATGTAAATACATCAAATTAATTTAGTTATGATAGCAGCCCCTAGTAA AACGGGACAGCTATATCCCTAAATTTGGTCAGTAACCTAGTACAAATACAATCCTCAAAA AGCTCCATACCTGAAATAAAGTGAGTGACCCCAATATCATAATTCTGAGTAGAATATTGC ATTCAATTTATTCTAAAAGTATACCATAAAGTTTAAAGTTTAAAGTCAGTAAGTGTATAA ATTTTGATTAAATAATTTGTCAAATAAAATAAAATTGCACAATTATCATCTTAAGCAGAC AATTATATGTATCTTAGTAAAAATATACATCTTCAAAATTTAGGAATTTAGGAGTGATTA TTAGTGCCATCATTCCTATGATTGTTTAAAAAATGTTCTTCTAAATACCATGCCCTTCTA CTGCTTTAAAGTCTATATATTTAGCACATATAGACCAAATAATAAAACTATTTATGCCAC ATAATACTTCTAACATTCCAATTAATGCCTAAATTGAAATCTATCCTGCCTATTCATCCA GTGTGGTCTGTGCTGTGGATGGCTAAAAACTTTGGCCAAAATACAAATAGGTGATACAAC ATCATCAATGTAATAGATCCGTATTTCACTATCTTTACCTTAAATTTCTGTATTATTGAA TTTGTGCAATATTACACGTCCCTAATATGTTTATACTGTACTACAAAAGTTTACAAGACA ATTATACATAAATCATCTCATTTGGTTCTTACGACAATGCTGTCAAGTAAAGTACTATTA TAATAGTCATTTTACTACATAGCAGTGTAACAACAGAGACAAGACTCCTGTTCAGATTTT GATTCCAGCTCCATCATTATTCATACATACTTTAAACGTATTGTTTAGCAGACAAGATGG TTGATATACATTTTGAAATTACAATATTTTGTAGCATAGTAAATTTTGTAGCATAGTAAA TTCAATTAGAAAGGGCAAATGGAAAAAAAAGCCACAGATCCATACAGAACATGGAAGAAT GAAATATGGTTAATTTGAATAGTTTGAATTCTAAGGTAACTTCATCTACTGTTATCTAGC CCAGACACAAAAGTAAGATTTTTAAAAATAAATTTCATGGCCAGTTTTTCTGCTAAAATA TGAAACACAACAAAAAGTACCAAATCAGAAAATATGACTTTTTTATCTTTTTTCTCAAAG GAGTTGTAGTAGGTTACATATTTTGTACATTTGACAGTAGTCAAACCAAATACTATTGTA AAGAATAAGGAAATATTTATTTTAAAATGGCATAGTTTTTGTATTTCTTCCTTTATCATA TTTACCTGTATAATGGCAGCATCTATGGATGCTTGTAAAACTGTGAAACCTGAGGACCAG TACTGAGCAGCCTCACATGATTTTGAACAGCCAGCTATGGGGGGAAGAATATGAGATCTA AGATTCTGTACAACATGCAAGTGCATCGTTTTAAAGATATTATATGGAGAGATACCTACC AAAACAATATAATCAATCAATCTTTACAGGACCAAAGAAATAAGCTACTGACTTTCAAAG GTAAACAATACTTACAAGATTTCTGATCATTTACTTGAAATTTTGAAATAAAAGTTATAT GTGTTAGAATACTAAATAGTAAATGAATAAAAATGTAAAGAAAGAAATTAATTGTAGTTA TTTAAAACAAGTTACTTTTTTGTTTTAAAGTAAATCATTCTACATGACTTAGCTCTAAAG CACTTCCAGAAGCAAGGAAAAGTCAAAGTTAAGCAAACAGGAAAAAAGAATTTTCAGAAG GGCTTTTTGAAATAAAGTCACAAATTCAGTATTTAGCATAGTGACTTTAACATTGCTCAA TAAATGTTTGTGGTTGATAATATTTCTTCATAGATTTAAACAACCAAAGGTTGTTTCCCA TGTTTCAAATATAAAACTAATCAAGTTCACTAGTAGAAGACCTCAAGATTTTAAAGATTT GTACATACCACAAGTAAAAACAATTACATGAAAAAAAGAGATTTAGAAAGTCATATAACC CAAAATGCAATTTTGCTTTATGCTACTGTATTTAATATATATAAATGTATTAAATCAAAA TGGGTATATATAAAAATGTTTTATGTGTAGAAGTAGATAGGTATTTATAAATAAATATTT TTATGCTATACTTCTCAGTTTTCCTATTGGAACAAGTAAGAATAGTTGAAAATGCCAATA TTGAACTATATAAAATTTTGACTATGAACTGCAAGCAGCAAAGATATGCATTTAATTGAT CTTCAATGATTATGTAGGGCTATTTACCTCTTGAATCCATATAAATAGAAGATACTGGAA TCATATCAGGAAAAAAACGAAGTTCATAGGACATGGAGTCTTTGAAAACCACACCTACAA AGTTGCTCGGCTTAGAGAGACTGGATGTTAACATTTCTTTTTCATTTGTATATTCTTCAG TAATTATGACTGTAAGATATCATAACAATATAGTTAGCTCACAAATTAAAATACCACAAT ACAGTAGATCAAGTTTACAATTATTTTGATGAATGGAATATTTTATAAACACTTTTGCTA TATTTACTTCTTAAAAAATGAAAACAGTCCAAGCACAGTGGCTCACACCTGTAATCCCAA CATTTTGGAAGACCAAGATGGGAGGATTGCTTGAGCTCAGAAGTTCAAGTCCAACCTGGG CAACATGGTGAGGTTCTGTCTCCAAAAAATAAAAAAATTAGCCAGGTGTAGTGATGTGTG CCTGCACTTCCAGCTACTTGGGAGGCGGAGGTGGGAGGATCATTTGAGCTAGGAGGTCGA GGCTGCAGTGAGCCATAACTGAGCAACTGCACTCCAGCTTAGGCAACAGAGTGAGACCAT GTCTCAAAAAAAACAAACAAACAAAAAGAAGACAATTCTTCCAACAAAATAATAATAATA AAATGGTACAATGTTGCAGACACTACTCAGCTGTCATTTGATTACAGAAATGTGTCAGTG TTATACTTATGTTATAAATATATGAAATATAGTATAAAACAATATGCAGAACTCATATTT CTTCAAGAAATTGCTGTTTCTCAAAACCTCAATTAATTATACTAATTTCAGGCAGCAATA AAATTATAAAAATTATTAGTAATGCAGTTCATTTATCTATCTCGAAGTTAAACTAAAAAA TAACTTCGTTATTTTATTTTATATTTTTTTAGAGACAGGGCTTTGTTCTGTTACCCAGCC TGCAGTGCACTGGATCTTGCACTCAAACTTCAGGGGTCAAGAGATCCTCCCACCTCAGCT TCTGGAGTAGAGCTTGGTCGATAGTCACTCATCACCATGCCTGGCTAATTTTTTGTTTTT AATTTTGGTAGAAATGAGGTGTCACTACATTACCCAAGCTGGTCTTGAACTCCTGGCCTC AAGTGATCCTCCCACCTGAGCCTCCGGACTAGTTGGGATTACAGGCATGAGCCAGTGCAC CTGCACAAAAATAACTTTTTAGTAAATATATGAATTTTTTATTTTTAAATATTTCTTATA AAGAAAATTCCACAATCCTTCTCAGAAACTAAATAGGCATTTTAGTAACTATGACACAAC TCCTCCTTAAATAAAAATTGTCATTCAAATCCAATATTGCTTGTTCCTTTCTTAGAAGAT AAGTGGAAAAAATACTGTAATCATTCTTTCTCATCAGATAAGACTAATTTTTAAATATTT TCTTGTAGTTTTGTTTACAAGCAACTAATTTTCACTACAGAAGCTTCAAACATGTGGTGA AATGGAAAGAATATAGAATTAGTACTTAACGTCTTCATGTATTAACTGTGTGAGCACAGA CAGGCGATTTGAACTCTTCAGACTTTAGTGTCCTCATCTACAATGCCTAGCTGATGACAC TGGGTTGTTGTGAAGAACAAGTGAAGTAACAAACATCAAAACGCTTTGTAGGCTGGATGT GGTGCCTCACACCTATAATGCCAGCACTTTGGAAGGTGGAGGCAGGTAGATTGCTTGAGT CCAGGAGTAGATTGCTTGAGACCAGCCTAGGTAGCATGGCGAAACCCTGTCTCTACAAAA AATACAAAAATTAGCCAGGTGTGGTGGTGTGCACCTGTAGTCCCAGCTACTCAGGAGGCT GAAGCGGGAGTATCACTTGAGCCCAGGAGGCAGAGGCTGCAGTGAGCTGAGATCACAGCA CTGCAAACCAGCTTGACAGTGAGATCCCATCTCAAACAAAAGAAGAAAAAGACAAAAAAA AAATGCTTCATAGATTCTAAAGTATTACTTAAATGTTAATTAATAGATTTTCCAGGCCTT TTAAGAGGGACAGGGAACTCCAGGATTTACATGAATAAAGAGGGTGTTAGTTCAACATCC TACCAGTCATGTTATGTATGTATGCATAACCCATTTTCAGATAGTTCTGTTGTTAAAAAT ACAGAAGTCTAAAAAAATTTGTGTATATGTATACACTATTTTGGCATCTAATACACACTG ACTTAGTTGTTTTTTGTTTGTTTGTTCTTTTTTTGTTTTGTTTTTTGTTTTTGAGATATT GAGTGTTGCTCTGTCGCCAGGCTTGAGTGCAGTGGTACAATCTCAGCTCACTGCAACCTC CGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAACCTCCCAAGTAGCTGGGACTACAGGC ACCCACCACCATGGCTGGATAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATG TTGGCCAGTCTGGTCTCAAACCCCTGACCTCAGGTGATCTGCTCACCTCGGCCTCCCAAA GTGCTGGGATTACAGGCGTGAGTCACCATGCCTGGCCTCATATTTCTTTGGTTTATATTC TTTCCTCCTACTCAGAATTACCAATGAATTTCATTTCAACATTTTTAATCAGCTTTTTGA GCTTGTACACTAAATTCTCATGGTAATCTATACTACTTGTACCTAATATGATACACTACC ATATAACAAGAAGTGTATTTAATCAAAATATTAAATAGAAATAGCCAGAGAAAGAAACCA ATGGAATAAAAGTTACCTGGCTTCTGACTGTATAATTAACACTTTCCATTCAATGACATA AAATCCAATAATGCGATGACATATAAGCTAATTACAACTATCCCATATGGCAAAAAATAA CATGCTAATCTGTCATTTTCTACAATTTAGCACTTCCTTGTTTAATCATTAATAGCATAA GAATTTCTGTCACTTTCTCCAGCTTTTGCTTTAGGTTCTCTCACAGCCACTTTAAGTTCA GTGGCACTTCACTGCTTACACTGTTTTCTAGTTCATTTCTTTGTGAGAAGTGCACATTGA GAAAAAAGACTTAGGTGGCACTTTAGGTGGAGGCCAAGGGAGGAAGATCATTTGATCCCA GGAGTTTAGACCAACCTGGGCAACATAGCAAGATCCCATCTCTACAAAAAATATATATAT AAATAAATAAAACAGAGTTAGGGACTTAGCCATAGTCATAGTTGTAGTCTCCAAAGTTAG GTACTTCTTCAGTTTACACCATACACTTCTATAAACAAGCATGGTAAGCTGAAAAGGTGA CTGCTTTACAGTCTTTATCACATATTTCTAGCTTCCTTTTTAAATTTTTTATTGTTATAG ATGGGGGTCCCATTCTGTTGCCCAGAGTAAGGAGTGCTGGAATGAAGTGGCATGATCATA GTTCACTGCAGCCCCAAACTTTTGGGCTCACGGGATCCCCCCACCTCAACTTCTTGAGTA GCTGGGACTACAGGCACATGCTACCACATTCAGCTAAACATTGCTAGCTTCATAATTATA TGAAAGTCAGAATCAAAATGAAATAGCCCATCAAAGCTTGTATCTTATACAAGTATACTT AAACTATTTTATAAATGGTCTAAGAATTAAATATAAAAGTACATAAAATATGCTTCCTAC CACCAAGAATATAAATTAATGTTTCACAAGAAAAATAAGGCAACAGAATTAAATAATTTT AGTATTTTTATAAAACTGACTTTGGTGGAGGAACACATCTCTAAGTGTTAAGACTGCTAT TCATTCAATAAAGCAAGCTGATAAATATTGAAAAGGCTTAATATTATAAACAGAATATAT ATATAAGCTCACAATACCATCAGGTAGATGATCAGTAGACACTTTCTGCATGATGCTGCT TGTAATATTAGTCACTGGAGTATATCCAAGAATTAGATTAGAAAGAGTAAACTTGTCCAT AGGATTGAGTTCTATATTAGGCACTTCTTCATATTTCTTATTTGGATGCATCATGCTAAT TAATATTAACCAAAATAAAAAAAATAGTGGAAAAAGAATTTCCTACAATAAAAGAAACAA AGTAATTACAAAGTATAACAATGGCAGCAAAAATCATCAAGATTTCTTGGCAAATAATAT AATACTAAGAAAAAACAGGAAATTTGGTTGTCCTTTCTTATGAATAAAATAAAAGCAATT CTATCCCAAAAGAATTTTGTGTTGAACACCTCATCCAACCCAACATGCATATTATTTTTT CCTTTGTATTTAGTTTTACTGAAATATTTTAAAATTCAAGTCACAAAATAAATTAAGGTG ACATAAAAGATAATATTTAAACATCTTAGATTATTGACATAAAACATAATAAATTTACTC ATATAATTTTATCTAAAGCAATTTACCGAACATCCCTATATGGATTCACCATAAAAATGC CTTTATTCAATTCTGAATTAGAAATCATACTTTAATTATACCTAAATGTATACTACCAAA ACCATACTGAATTAAATTCTACGGTCAGTTTTAGTAGAAATGAGCTATTATATCATCTTG CTGTTTAATTGTTTTACCAGTTTCAGGGAAGATGAATAATATGTTTTCATCCTTTGAAAT TATTACTAGCTGGTTACCCAAGTTCTTCCTTTCTTTTACCCTTATCAAAAGTAATGTATG CTGTGGGTACAAATCTGTGTCATAATATTAATACTCATGGGCAACTCAATCTAGAGTCCA TAAAATACGAGGTTGTGGGATATAAAACTCTGGAATCAAAGTTATTGTGGAATGTTAGTT CATGAAACTTAGGAAACACATGCCTAAAAGCTGAAAATGAAGCACAGATGTTAGAAATTA ACTAAATGTAGAAATTATTATTAAAATTTTTAACATTTAGAAAGCATTAAGTAATTCAGT TATTTTTCTGTGGCTAACATGGCAAGCTTTTACTTTACAAGCAAAGAAAAATAAAATTAT AATAAAAATATATTTAGCAAAATAAATCATCACTTCAAGATAGAATATATCAAGCAAAAT AAACTGCAAAAAAGCATAAGAAAGAGTTATTTAACTTACCTGAACACTACTCTTTTTGGT TCTGCATTTAATTAAGTAATTCTTCAGTAGAAGTGTTCTGGTCTGTCTCCAAACTCCTAC CTCCCTAATTGCAGTGGACATGTTTTCTGAATAAACCTATTAAAGAGGAAAAACAAACAA ACAAACCCGGAGCCACGCAGTAAACTGCATGTAATTTTTAACGGCAAAATAAGCAGCTGT TTCAGTCCCAGGTAAGATGGATTAAGCATACTCCAAGCTGTCTCTCTTAGGAAACTGGAC AGAATGCATGGAGCAGCAATCTGTCAGCTCTGAAAAGTAAACAAGGCATGTGAAATAGGG TAGACCAGAATTTGAAATACCACCATATCAACAGTGGTACTTTTTCTCCTTTGGTATCTC CCGAACCGCCCACAGAGGCAGCTCCAGAAGAAGCCTTAGCTTTGAATTGAGGAATGGGCA AGGGAAGTCTTAATGCTCAGGGAGAATGTAGAAATAGCAAATCTTTTTTTCTTTTCTGAA TTCTCCTGTATCCCCACATGCAAGCAATCCCATGGTAACAGGGCCAGACTACAGTAACAA AAGCCTAGTGCAGCCAACACTCTGAGGCAGGAAAACCTTTCTCTCTATTCAATGGAACTA TCGTTGTAAGAGGATGAGGCCAATCCCTTTTGCTTTTCTTCTCTACCTCCTACCATTGGG CCCTGGATATGGTGGTTGCAGCTGCACAAGTGTGTAACACAATGGAGAAAATAAACACTA GCTCTCTGGCTGGAGGATAGAAACAGCAGCCACAGGGAAGCAAAAAGTAGAAGGGGGAAC AAATAGAAAGAGAGCTCAGGAAAGCACTCTAAAAAGTTGTTTTTAATTCCTGTAATAATT CCCAAGCTGGACATACATAAATCCAATCCTATTAGTGTGACAAAGGCTTGAGAAACTGAA CTAACAGACAGACCACTGTCCAAATCCAGACTGTTCACTGCAAGGCACACACAAGACAGA CCAAAAAGGTACTGCAAAAGTTTTTGAAAAATAAACTAAAATGACAACTACAGTTCAAAG AATGTGGGTAGAAACTTATGACCTGAACCTAACCTGGTTGACAGCCTGCTAAGAGAAAAT ATCAACATTTTCTGTAGGTATTAACACAAAACCCAAAGTCTCATACAATCCAATATTACA CTGCAAATGAAGCATGTAGAAAATAGCTGACCGGGTGCGGTGGCTCACGCCTGTAATCCC AGCACTTTGGGAGGCCAAGGTGGGCAGATCACGAAGTCAGGAGTTTGAGACCAGCCTGAC CAACATGGTGAAACCCTGTCTCTACTAAAAATATAAAAATTAGCTGGGTGTGGTGGCACA CACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGATCTGCTTGAACCCGGGAGGC GGAGGTTGCAGTGAGCCAAGATTGCACCGCTTCACACCAGCCTGGGTGACAGAGCAAGGA TCCGCCTCAAAAAAAAAAAAAAATAGCAACTCTACTAAGAAAATAAAATCAAAGATACCA ATGCTGAAATAACACAGACTTTGAAATTATCTGATAAAACTTTTAAAGCAGCTATTTAAG GGCTTCAGCAAACAATCGAAAGTACTCTTGAAAGCAATGAAAAATAGAAAATCTTAGCAA AGAAACAAGACATTAAGCAGAATCAAATGGAAATTTTAGAACACAAAAACACAATAAGAA ATAAATACAAATGGAAACTTTAGAACAGAAAAACACAATAATAAATAAAACTCATGGAGT GGCTCAAAATCAGAATGAACACAACAGAAAAAAAGTCAGGAAACTTGAAGATTATCAATA GGCATTATCCAATCTGAACAACAGAGAGAAAAAAGATTTTTAAAAAATTAACAGTGCTTC AGAAAACTGTGAGACAGTCTGGGCACACTGGCTTACGCCCATAATCCCAACACTTTGGGA GGCCAAGGCAGACAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTA AAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGTGGGCGCCTGTAAT CCCAGCTACTGGGGAGGCAAAAGAATCGCTTGAACCCAGTAGGAGGAGGTTGCAGTGAGC CCAGATTGTTCCACTGCACCCCAACCTGGGTGACAAAGTGAGGCCCTGTCTCAAAGAAAA AAAAAAAGAAGAAAAAAGAAAACTATAGGACAATAACAAAAAGTCTAACTTTCATATTAT CAGATTTATAAAAGGAGAGGAGAAAGAGTATTAATGCTAAAAAAAAAAAAAAAAAATTAA AGACTTAATGGCTGAAAACTTCCAATTTAGCAAGGGATATAAACACATAAGTTTCAAGAA AGTTGGTGAAGCCCAGAAAACATAAAGAAAATCCATGCCTATACACATTATAATTAGACT GCTGAAAATTAAGACAACAAAAAATCTTGAAAGCAGTCAGAGAACAATGATGTATTACCT ACAGAGAGTAACAATTTGAATGAGAGCAGACTTCTCATAAGAAACTGCGGAGAAAGTGGA ATACATTACTGGCGGGAAAGCAAATGGTTCAGATGCTGAGAAAAACAGTTTTACTATATG ACCTCACAATTCCACTCCTAGGTATACACCCAAAAGAAATGAACATAAGGACTCAATTGA GTACATGTTCACACACGTTCACAGTAGTGCTATTCAGAATAGCAGAAAGGTAGAAACAGC CCAAATACTTACCGACAGATAAATGAACAAACTGTGGCATATACATACAATTATTATTCA GCCATAGAAAGGAATGAAGTGGCTAGGTGCAGTGGCTCATGCCTGTATTCCCAGCACTTT GGGAAGCCAAGGCGGGTGGATCACTTGAGGTCAGGGGTTTGAGACCAGCTTGGCCAACAT GGCAAAACCCCGTCTCTACTAAAAAAAAATATACAAAAATTAGCTGGGCATGGTGGTACG TTCCTGTAACTCCAGCTACTCAGGAAGCCGAGGCAGAATTGCTTAAATCTGGGAGGCAGA GGTTGCAGTGAGCTGAGATTGCACCACTGCATTCCAGCCTGGGCATCAGAGCAAGACTCT GTCTCAAAAAAAAAAAAAAAAAAAAAAAGGAATGAAGTACTGCTATATGCTACAATTAAA ATGAACATACAAAACGTTATGTCAAGTGAAAGTCAGACTAAAAATGTCAAATGTTATATG ATTCCCTTTATAGGAAACTTCCAGAAAAGATAAATGTAGGGACAGAATGCCAACTGGTGA TTGTCAGAGGCCAGGGAGAGTAAAGAATGAGGAGAAACTGCTTACAAGGTAAGGAGTTTT ACCTTGGAAATAAATTTTACCTTAATAAATTACTTCAAAAAATAACATTGAATGATCTAA ATCATTGTACCTATCACAGGTCCAGTATCCCTCTTCCAGGGTACATTTACCCTTTGAAGA TCCTTGAAATCCTTTCTGCCTGTGGACCTCTATTGGAGCTATCTCGATTCTTCAGAGGTT TCATTCCAGCTGAACTCAAAATAGAAGTGGTCAGAGTCTCAACTGCAATGTCCACTGCCC CTATTCAAATACACTCAACCCAGTAACCTAGGATCTCTGCATACTAAGAAGTATTGAGAA GATAGCAGGGGAAATAACAACAACAACAAAAAAATCCTGTTAAACCTTCCAGAGAAATTG CTGTGCCCTTGTTTTAAATAAACCTATCTAGTGAGGCCACTGCTATAACTCTCCTCCAAA ACAAGGACCATCTGTTGCAAGCTGGAAGACTGTCTACACCTAAATAAAGAAAACTCACAA TTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTTTTGTCCAGGCTGGAGTGCAATGGCAC AGTCTCGGCTCCTGGGTTCAAGCAATTCTCCAACCTCAGCCTCCCAAGTAACTGGGATTA CAGGCGCCTGCCACCATGCTCAGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCACC ATGTTGGTCAGACTGGTCTCAAACTTCTGACCTCAGGTGATCCATCTGCCTTTGCCTCCC AAAGTGCTGGGATTACAGGAGTGAGCCACCGTGCCTGGTCCATAATTTTTGAGAGGCAGT TTGTCTTTTCCAGTAAATATATATAATTAAAGTTTGGCTTAAATGAGCATCTTCTTTATA TGCACAGAAGGAAGACTGGAAAGAACTGTTTAAATTAGCAATGGAATTAAAGACAACTTT TATTTTCTTCATGCTTTTTTTCTATGTATTACTTACATAGTAAAAAAAAAGCAATTAAAC AATTAGACATACTGTAAAAATACTAAATGAGTAAATTAAAAACAGCAAAACAAAAGCAGT CAAGAATAGAAGATACATTAAAATAAATTCTTCCAGCATTCCATTCCAAGGCATCTGTGA ACCTGTGGAGTAGACACCATGAGCAAAGCTTACACTCCCGAGTTGAAAAAATTGATGGAC AAAAAGTTATCATTGAAAATTAAATGGTGGCAGACATGTCCAAGGAATATTGTGGGGATT TGATCCCTTTATGAATCTTGTGATAGATTAATGTGTGGAGATGGCAACTAGTGGGCAACA GAACAATATTGGAATGGTGGTAATGCGATGTAATGGCATCATCATGTTAGAAGCCTTGGA ACAAGTATAAATAATGGCTGTTCAGCAGAAAAACCCATGTCTCCCTCTCAAAAGGGCCTG TTTTACTATGATGTAAAAATTAAGTCATGTATATTTTCATATTAGACTCTGTTAAATAAA CTTCTGTAATGGTCAATAAATAAATTCTTCTAACAGTCTCAACTATGTTATATCACATTT AGCAAAGAGTTGATAATAGGAGGGAAGGAAGGAAGAAAGCTGTACTCATTCAAGCATTAT TTGCTACAATACAAACATAGAAACACTAACCTAATGCAGCATGAACATTCTCAAGTTACT TGCCAAAACACATTGATTTTGTGAATGCTACTAAATTATTAATCCACTTTGAATGTTGGA TGCTTAACTCTTCATTTTTATATAACAGACTCATAGAGTAGATGGATTCACAGAATTTTT TGTTTTTTTGAGAACTGCTTCCTGAACTCAAGGTTGAGTCTCTAAGGGCCTTGTCTAAAA AACCTGCCCACCCACTCCACCTCTCATCACAGCTTTTTAAAGCAAAACTAAACCAACTCC CCAAACACCATCCCAACGCACACAAACCATCACCACCACCACCACTACTCTTGAGCTGTG TCAGTTAAAATTTCTCTTGGCAGAATTAACTAAGAGACCCACAGACTGGATGGAAGTCAA GGAAACTGAATTACATGAATGGCAACATTTAAGAAAGAAAGTTTACACATTCTTACTCTA AGCTTTCTTCTAATGTACCACACCTACTGTGCTCACAACTCGATTTTTCTTCCTTGGAGT ATGTGAAATGTCCTATTATCTTCCCAATATATTTTCATTTTCACTTAAGCTAACCAGTAT CAGATTCTATTTCTTGCAAAAAAGCATCTTAACCAATATTACAAAGGCACCAAAATTAAC AAACATAAGAACTAATAATGCCCAAAGTAGTATAGGTTAAGAGTATGACCTCTGAAGCCA AACCAACTAAACATGAATCCTGCCTCTGCTACATACTAACTTCAAGACCTTGGGCAAGTT ATTTAATGTTTTTGCGCCTAAGTTTTATTATCTGTAAAATACAACAATAGTAGTACCTAC CTCTTTGGGTTGTTAAAATGACTAAAAGAATTAATACATGAAAAGCTGAAAATGGTGGCT TGTACATGGCAACTAATTATACACATTGATCACGATTGTGTATAAAAGTATAACTAATAT CCTTAAAAGAGTAATAGAGAATATCATATTCTTGGAACAAGAGAAAGATAATTAAGAAAA AAGCAATTACAGAACTTAGAAATGAAATAAAAAACTGATAGAAATAAAAAAGCACTAAAA GATGGGGTGAACTTCATTTAAAGACGAATTAGTGAGCTAAATTGAAGCGTGAGTCAAAGA AACCCTACAGAATGAATTGCAAAAGGACAGAGAGAAAAAAATGATGAAAGTATTAACTCT GTCATCAAATTATACCAATGACTCAGTATTATGAATGACCTCAACAATCTGATTTTTCTT ATACTCAAAAGCTTTAGTCTAATCATATGAAAATATTAACTTTCAATAATCTTGAGCTTC AATTCAAGTTATTGAAACAAAAAAAAAATCTCTTAAGCCCATCTGATCACTGGTTTTCTT CATAGTATGAAATACATGGTTTAGCTGTTTGATTGAAAAGAATGAAACATTCTTAACATT AATTCTTCATAAACCTTTAAACTTTAACGTTGATCTAAAACAGAAACTTCAAAGCTATAG TCAGGTCTTTGTAAACTAACCCAACAACGTACCTATTCACCCTCCTCTTTGCCTGCTGCA TCCTCCAACCTGCCAGTCCACAGTGTCTAAGCAGGCCCAATTTGAAAAGGGATATGGCGA ATAAATAAGCAAGGACTGGTCTGCATAATAATGTAAACACTAACTCTACCCTATAAATTC TTTGCAAATGATGAGGTGCTGGGGAAAATATTTGGCTTCCTTTTCAGGTGTCGAGACCAC ATTGTCTCTCGACAATTGGTCGAGAGATTATACCTGTCCTTTGGGGAGAAGACAGAGAAA CAAGATAGAATAAAAAAAGGGGTGATTACAACTCTCACTGATATGGTAATCACAAAGGCC CCTCTCTTCACCACATCCTCCACTGTTTTGCAGGGTCTGGAATCCCAAAGGACAATACTG ACTAGCCTAACAGGGAGTTAGGGTGGGAAAACTGGGATGAAGGAAGAATGTGGGAAGGCA GTACTTTTCTATATTGACGAACACCCAAAACTAAAGGGTTAATATCTTGAGATGGGAACA ACTCTTGTGGATGAAAGAATGAGGTTTCCAGAAAGAAAGGTGGAGATCCACACAGCAGAG GTGACATGAAAGCGGTGTTCCTGACAGAAGCATATATCTGAAAACAGGGCTGCAAAGTTA CAAATGAGGCATGACCAAAAAGGGGACATCTATGAAGGGTTTGACTTATCAGGTGCCTTT TCTTGGGATACAAGAAACCCCGTATTTAGCATGGAGCTATACATTTCCTCTTTCTATACT AGAATTCCAAAATTTTATAGCTTTATGTGATGGTTTTTGGAAGAATAAGAGAAAAACGCA GTAAAAAGATGCATGGCCTGCCTCAAGTTTAACTGTTTAAGTTTAATTGCCTCTAAATGG CAATATCTAGGAGTTCACTCACTAGCAGCTGAGTTAATACAAGACCAAAGCAGAATTTGT ATGGTTCCAACTCAAAATCTTACCAATGAAATACTTTAAAACACTCTTTAACAAAGCCAA TTCTTAGCTGTTAAAAAACAGTGGCACAAAGAGAAATACGGGTTCAAAATCTAAAAAAAA AAAGTTATTTTCCATACTTCCACAGCATACCTGAGAAATGTGCTAAGTTTGTTGTAGGGC TTTAAATAATAATTAGGTGAGTTTTAAACACCTAACATCTCTAAAGATTTAATCAAATTT AACTTTCCTAGATAAATAATTTACTAGATAAAATAATTTATACTAAATCCAATAAGTTGC AAGAAAATGGAAAGCCTACTAAAGCCCATCTTCCTTTTCTAATGTATTAATTGACTTAAA GACCAGGAGTTGCATAATCCAAAGTTCAATATCAAAAATTCACTTCTTAATTTATCTTAA AGTACTGGTTACTACGGCCAGGCACAGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAG GCTGAGGCGGGAAGATCACGAGGTCAGGAGACAGAAACTATCCCGGCCAACATGGTGAAA CCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCGGGCACCTGTAATCCC AGCTACTCAGGAGGCTGAGGCAGGAGAATCACTCGAACCCGGGAGGTGAAAGTTGCAGTC AGCTGACACTGTGCCAATCCAGCCTGGCAACAGAGCAAGATTCCGTCTCAAAAAAAAAAA AAAAAAAAAAAAAGTGCTGGTTACTACGTTCCAAGTCCTACGAAACATATTCCACATCAC TAAAAGTAATAAAAATGTACATAACCTTTAGAAATAATTGTTAGAGAAAAATTATTTAGG ATGCATGAATTTAATTAATTAAAATAAGAAATTTGAAAGCTATAAAGTATTTTTTAAAAT CTAAGGTAGTTCTACTATTATACCTACTGCCTTTGTTAAAAGCAGTGCTTTCCTTAGAAG AGCCTCTCTCTTCCCCCACCTCCCCCGCAAAATCCATCACTTATCTAATGATACCATTAT CTCCTTCAAATATTTTCAGCTAGTAAAACAACTCACTGCACAGCAGAGGAGGTACTAAAT ACCTGTGGAATAAACAATCCATTTATTATGTAGCAGGTAAAATAACTTTAAATTTTTTAA ATTATTTTCATAGAGACCTGATTAAAAACATATCCATGTTTATTTCTGTGAGAAACAAAT TAAGATTATACCCTATAAAATAAATAAGTTGAGTCATCCTGATGTTTAGAGCCATCCTGA TAAGAAACGTGGTCACCTTCTTAGCATCCTTAAAAGATTTCCAGAAAGGCTAGCTGAAAA TACATTCCCTACCTCCAACAAATGACTGTTAGAGGTTACTTCTCATCCACCTAAGCAGAT GTAACAGAAAATGGATAGTCTGTCTACTTGGGGCTTCTAAACGTTGTTCGGCACTGAAGG TTGACTTTGGAGACTGGGTCATGAAGCTTGACCTCTTAATTACTGACCTTTTGTTATACA TGAAATTCCTTCCTTATTTTCTTGTTCCTAGATCACACCAGATGATGCCAGGGATAAAAG ACCGCTGACTGTGATAAAAGACCCTTTGACCATTACATCCTTAATGTGAAATGTTAAATA TACCCTTCCCCCAAAAAGAAACACTGCCTATAACTAATTGAATTGCTCTAACTATGCACT AACCTCGTACGAAAAATGATGTAACCCTGTTAAGCATCCCCAGGCCTTGCCTATGTAAAG GACCCTCAAACCTCTCCACTTTGGAGCATTTACCTCATCCTTCAGGAGTCTGTGTCCTCC TGTGTGACCATCCTCAAGTTTTATGCTCAAATAAACTCAATTTTTAATCATATTGCCTAA ATGTCATTATTAACATTGACATGGAGCTGATTATCACTCCTTTGTTTTACCTCTATACCC AGTAAACATAACTGTAACTGCAGTAACTATACCCTGTCACCATTATTTATTTATATATTT TCATCTTGAACTTGACCATGAGATCCTTGATGAAAAAAACAACAGTCTTATTTATCTTTG TTTCTCCACCACCAATGGAAATATTAAACCCAGTATCATCTTACCACAGATTCCTTTATC AAGGCTTCCTGAGAGTCCTTAAAGATCAAGGATGTGCAAACTATGATGAAAGAGGTGGGG GCTAAATCCAACCCTCAGTCTGTTTGGCACAGCCCATGAGGAACACTGCTTCTGCATTTT TAAAAGGTTGAAAAATAATAATAATATCTTGTGACATGCAAAAATTATATGAAATTCAAA TTTCAGTGTCTATAAATACAGTGTTATTGGAACACAGCCATGCTCATTCATTTATGTATT ATCTATGACTGCTTTTGTGCTACAACAGTAAAGTTATTGAGACAGAGACCATACTGTCTG CAAACCTAAAATATTTACTATCTGGCACTTTACAAAAAACGTTGGTCAACTCCTGTAAAA AGGAAGAAGAGGGGAAGTGAGAAAAGTGGCATATTCACTTAACATTTACTGAAGGATTTA TGCATCCAACATTATGAGGCAAAAAAAATAAAGTTAGACACTGTCACTAACTTTGCAGAG AGATAAAATTTAATATAATGTGATAAGAGAGAAAGAGCCTGGAAAGGAGTGGAATGGAAT TTCCAGGCAGAAAGAAAAGAATGGTAAAGCTAGACTCCCAAACAAAAGGGCTTGACTTTT GTGAAGAACAGGGATACCTGCCATATGGCAGAGGCATAAGGCAAAGTGAACCGGAGCAAG GGGTGCAGATGTATGTTCTAGATAACACGGTAAAGGCAGGCATTGGGAATGGATTATGAA GTTTCTGGTATCCAAAATTAGACACCCTAATTTGTGCACTCATATCTTTCCTCTACTGTA CTTTTCACAACTGTGAGTCATGTTTAATTTCCTAGCAATCACATATTCCACTAGTCCATC ACTTTCCCAATCCCCAAATCTCCAAAGCTTCCATCTGTAGGATCACCCTCAGATTATGAC CTTGAATCCTACTTTACTGAGAAAACTGAAGCAATTAAAAGAGATTTCCAAAATCCACCA CAAAGTAATGTTATACATTTCAACAATGTGCCATTTCAGCCTAAACTGAAGACTGATTTC ATTACAACTCTGAAACACAAGAAATTAAATGCAATCTGGTATTAGCTACACTTTTAAACT AAGATATTTTTGGAATGAGAAATTAGGAACATATCTGGCACATGAAACAAACTCCTGCCT AGCTACATCATTTGCTTCTCAATCAATGAAATAAAAGCACTACAAAATATGCCTTTTAGC TTAAAAAGGGATAAATTATAAATGCTCTCATCTTCTTTATTGCTTTAAAATTTACTGTAA GGTGGTGCAATAATAAAACAAAATGCAGTCAGGTGCAGTGGCTCACGTGGCAATCCCAGT GGGAGGAAGGCTTGAGCCCAAGAGTTCAAGATCAACCTGGGCAACATAGAGAGACACTGT CTCTACCAAAAAAAAAAAAAAAAAAATAGCCAGGCGTAGGGGCACACAACTGTGGTCCCA GCTACTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCTGCGAAGTCAAGGCTGCAGTGA GCCAAGATCCTGCCACTGCACTTCATCCTGGGTGACAGAATGAGACCCTGTCTCAAAAAA AAAAAAATGCTAGTTGTCAATATAATTTAACCTAAATTTTATCACAGTGTTTCTTGCTGA GGGAGAAAATAACAATGCAATGGTACACAGAGGACAAGTCATCCAATAAATTTTCTTATG CATAATAGGTCCTTAAAAGCTTGCCCTTAAAACTATTTTTAATCCAACTAATTTACATAC TAGAAAAGTTATGACTTAGTACAATATCATAAAATTCTTTTATGCAATCACCCTCTCAAC TAAACTCAAGGACAGAGATTATAAATTGTATTCATATCGGTACTCTTGGCACATAGTATG GTATCTGGAATGTAAAAGACATGCAACAAACCAGCCTGGGCAATATAGCAAGACTTCGTC TCTGAAAAACAAATAAAAAATTACCTGGGCGCAGTGACACACGCCTGTAGCCCCAGCTAT TCAGCAGGGTCCCTAGAGTCCAGACGTTCAAGGCTGCAGTGAACTTTGATCGCACCACTG CACTCTAGCCCGAGACGCTGTCTCTTTAAAAATAAAAGACATGCAATACACATGGAATGT ACTAATAAATTTGCTCTTATAGTGAATGTAAGATTTCCCTACACTAAATCTGTTTGAAAG GAAATATACTCAAACAGCACATATGCAAAGATTAACGCCTCTTTAGTTTGATTTTAACAC AAATACCCACAAAGCCCTAACTGCCCTAATAATGTTCCCTACTATGGAGTCTTCCCTAAA ACACATACAATATTGCTCTCCCGGCAAACACAAAATATACTAAATAAAGCACCAGAATTA GGGTCTGGCAGCCCGGGTTGGAATCTCAACTCCATCCTTTTACTAGCTGAGACCTTAATA AGTTACTTAACCTCTTTGAGGCCCATTCTCCACACCTGCCCAACTGGAATAACCCCCTCC AATCCTACAGGGTTGCTGTCAGAATGAAAAGAGCTAATACCGAGCCTGGCTTAAAGCTGT AGTCCAGCAAATACTCCTCTTCCCTTAGATTCCTTCAGAACGCCCTTGTAGAAAGTAAAC GTGGTTATTATCTTCATTATTTTCGGACTTATTTATTTAAAACGTAAATCGAAGCCTGAG GAGCCCAGGGGAAAACCTCCTTCAGCTTAATAGCTCCAGCCTGCCCAGCTTTCCGATCCA ATTAAGTATTTCCATGCCTGGAGCTCCTATTCGTGTTTTAGGATCAGGGAATTTCCCTCC CAAACTGTGTCATGAGATCTGCGCATTTTCTTCTCACTGAAACTCCTTTTAACACGCAAG GTAATGATCCGCGCGTAACCTCGCAGGGAAGAGCAAGCGCTCATTACCCAGCTGTTCAGA CGGAAATTTACATCAATATTTGTTTTCCTTCTTTCCCTGAGGTTGCTGAGGGTGGAACGA CAGCGTCCAGGCAAAGGCAGTGTCCCGAAGTCCCACGGCCGGACCCGGTCCCAGGGGAGC CTCGCGGAGCCCCCGCCGCAGGGCCCCGACCCCCTCACGTCCGCATCCTGGGCGCTCCCA CCGCATCCCCGAGGCTGGCAACCCGCGCTTCCCGGGAGCTGAGGGAGGTCTGTTTCCCTC AGCTCGCCGCCTCTGCCCGCTTCCGAGCCCGCTTCACCCCACACCTCAGACGCCGAACTC CCCTTCTCTCCCCGCCGTCCCTCGCTGGCCAGCCCCTCCTCGTCCCCTCAACTCCCCCAG GGACGGCTGTCCCAGGCTAGCCTCAAGCGCCGCCGCCGCCCGCGACGCCCGCCTCACCTC AGGGCCCGAGCCGCAGAGCTGTCAGGCCTGGACGCGCTCAGTCTGTTGACTCAGTGCGGG TGACCCAGCTGGGATCTGTGCGAGGGCGCGGCCGCGCGCACCCGCGCGCTCCTGGCGCAG GCAGAGCTGGCGGCGCCGAAGTCGCGCCCCGCCTCCTGCAGAGCGCACCTGAGGGCGGGG CTCCTAGAAA bcftools-1.21/test/csq/ENST00000269081/ENST00000269081.fa.fai000066400000000000000000000000231467060157400215360ustar00rootroot0000000000000017 180130 25 60 61 bcftools-1.21/test/csq/ENST00000269081/ENST00000269081.gff000066400000000000000000000314701467060157400211660ustar00rootroot0000000000000017 Ensembl chromosome 1 14110327 . . . ID=chromosome:17;Alias=CM000679.2,chr17,NC_000017.11 17 ensembl_havana gene 100 97732 . - . ID=gene:ENSG00000154263;Name=ABCA10;biotype=protein_coding;description=ATP binding cassette subfamily A member 10 [Source:HGNC Symbol%3BAcc:HGNC:30];gene_id=ENSG00000154263;logic_name=ensembl_havana_gene_homo_sapiens;version=17 17 ensembl_havana mRNA 893 97732 . - . ID=transcript:ENST00000269081;Parent=gene:ENSG00000154263;Name=ABCA10-201;biotype=protein_coding;ccdsid=CCDS11684.1;tag=basic;transcript_id=ENST00000269081;transcript_support_level=1;version=8 17 ensembl_havana three_prime_UTR 893 1712 . - . Parent=transcript:ENST00000269081 17 ensembl_havana exon 893 1811 . - . Parent=transcript:ENST00000269081;Name=ENSE00003592115;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003592115;rank=40;version=1 17 ensembl_havana CDS 1713 1811 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 1919 1974 . - . Parent=transcript:ENST00000269081;Name=ENSE00003547375;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003547375;rank=39;version=1 17 ensembl_havana CDS 1919 1974 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 2870 2949 . - . Parent=transcript:ENST00000269081;Name=ENSE00003512568;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003512568;rank=38;version=1 17 ensembl_havana CDS 2870 2949 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 4929 5069 . - . Parent=transcript:ENST00000269081;Name=ENSE00003470019;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003470019;rank=37;version=1 17 ensembl_havana CDS 4929 5069 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 5248 5367 . - . Parent=transcript:ENST00000269081;Name=ENSE00003560839;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003560839;rank=36;version=1 17 ensembl_havana CDS 5248 5367 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 6191 6285 . - . Parent=transcript:ENST00000269081;Name=ENSE00003635211;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003635211;rank=35;version=1 17 ensembl_havana CDS 6191 6285 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 6357 6432 . - . Parent=transcript:ENST00000269081;Name=ENSE00003467871;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003467871;rank=34;version=1 17 ensembl_havana CDS 6357 6432 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 6717 6895 . - . Parent=transcript:ENST00000269081;Name=ENSE00003560184;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003560184;rank=33;version=1 17 ensembl_havana CDS 6717 6895 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 7121 7212 . - . Parent=transcript:ENST00000269081;Name=ENSE00003603676;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003603676;rank=32;version=1 17 ensembl_havana CDS 7121 7212 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 7905 8022 . - . Parent=transcript:ENST00000269081;Name=ENSE00003586261;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003586261;rank=31;version=1 17 ensembl_havana CDS 7905 8022 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 8691 8811 . - . Parent=transcript:ENST00000269081;Name=ENSE00003542006;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003542006;rank=30;version=1 17 ensembl_havana CDS 8691 8811 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 9718 9809 . - . Parent=transcript:ENST00000269081;Name=ENSE00003601797;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003601797;rank=29;version=1 17 ensembl_havana CDS 9718 9809 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 16960 17040 . - . Parent=transcript:ENST00000269081;Name=ENSE00003648384;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003648384;rank=28;version=1 17 ensembl_havana CDS 16960 17040 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 17850 17969 . - . Parent=transcript:ENST00000269081;Name=ENSE00003641662;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003641662;rank=27;version=1 17 ensembl_havana CDS 17850 17969 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 27167 27280 . - . Parent=transcript:ENST00000269081;Name=ENSE00003478898;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003478898;rank=26;version=1 17 ensembl_havana CDS 27167 27280 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 27493 27663 . - . Parent=transcript:ENST00000269081;Name=ENSE00003688714;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003688714;rank=25;version=1 17 ensembl_havana CDS 27493 27663 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 28292 28399 . - . Parent=transcript:ENST00000269081;Name=ENSE00003498536;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003498536;rank=24;version=1 17 ensembl_havana CDS 28292 28399 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 35039 35176 . - . Parent=transcript:ENST00000269081;Name=ENSE00003649214;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003649214;rank=23;version=1 17 ensembl_havana CDS 35039 35176 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 35561 35694 . - . Parent=transcript:ENST00000269081;Name=ENSE00003557395;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003557395;rank=22;version=1 17 ensembl_havana CDS 35561 35694 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 38363 38529 . - . Parent=transcript:ENST00000269081;Name=ENSE00003546928;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003546928;rank=21;version=1 17 ensembl_havana CDS 38363 38529 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 40567 40765 . - . Parent=transcript:ENST00000269081;Name=ENSE00003544102;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003544102;rank=20;version=1 17 ensembl_havana CDS 40567 40765 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 43244 43363 . - . Parent=transcript:ENST00000269081;Name=ENSE00003648603;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003648603;rank=19;version=1 17 ensembl_havana CDS 43244 43363 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 44062 44201 . - . Parent=transcript:ENST00000269081;Name=ENSE00003558556;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003558556;rank=18;version=1 17 ensembl_havana CDS 44062 44201 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 45449 45539 . - . Parent=transcript:ENST00000269081;Name=ENSE00003619697;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003619697;rank=17;version=1 17 ensembl_havana CDS 45449 45539 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 45996 46134 . - . Parent=transcript:ENST00000269081;Name=ENSE00003506184;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003506184;rank=16;version=1 17 ensembl_havana CDS 45996 46134 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 46379 46498 . - . Parent=transcript:ENST00000269081;Name=ENSE00003578362;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003578362;rank=15;version=1 17 ensembl_havana CDS 46379 46498 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 46700 46875 . - . Parent=transcript:ENST00000269081;Name=ENSE00003538588;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003538588;rank=14;version=1 17 ensembl_havana CDS 46700 46875 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 47271 47381 . - . Parent=transcript:ENST00000269081;Name=ENSE00003661242;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003661242;rank=13;version=1 17 ensembl_havana CDS 47271 47381 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 49950 50008 . - . Parent=transcript:ENST00000269081;Name=ENSE00003473607;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003473607;rank=12;version=1 17 ensembl_havana CDS 49950 50008 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 54386 54554 . - . Parent=transcript:ENST00000269081;Name=ENSE00001014916;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001014916;rank=11;version=1 17 ensembl_havana CDS 54386 54554 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 67590 67737 . - . Parent=transcript:ENST00000269081;Name=ENSE00003562941;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003562941;rank=10;version=1 17 ensembl_havana CDS 67590 67737 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 68701 68886 . - . Parent=transcript:ENST00000269081;Name=ENSE00003476231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003476231;rank=9;version=1 17 ensembl_havana CDS 68701 68886 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 69103 69244 . - . Parent=transcript:ENST00000269081;Name=ENSE00003516561;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003516561;rank=8;version=1 17 ensembl_havana CDS 69103 69244 . - 1 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 72431 72657 . - . Parent=transcript:ENST00000269081;Name=ENSE00003538790;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003538790;rank=7;version=1 17 ensembl_havana CDS 72431 72657 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 74678 74781 . - . Parent=transcript:ENST00000269081;Name=ENSE00001105057;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001105057;rank=6;version=1 17 ensembl_havana CDS 74678 74781 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 75419 75583 . - . Parent=transcript:ENST00000269081;Name=ENSE00003346005;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003346005;rank=5;version=1 17 ensembl_havana CDS 75419 75583 . - 2 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana CDS 78211 78244 . - 0 ID=CDS:ENSP00000269081;Parent=transcript:ENST00000269081;protein_id=ENSP00000269081 17 ensembl_havana exon 78211 78415 . - . Parent=transcript:ENST00000269081;Name=ENSE00003503855;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003503855;rank=4;version=1 17 ensembl_havana five_prime_UTR 78245 78415 . - . Parent=transcript:ENST00000269081 17 ensembl_havana exon 80031 80171 . - . Parent=transcript:ENST00000269081;Name=ENSE00001372518;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001372518;rank=3;version=1 17 ensembl_havana five_prime_UTR 80031 80171 . - . Parent=transcript:ENST00000269081 17 ensembl_havana exon 81467 81746 . - . Parent=transcript:ENST00000269081;Name=ENSE00001377394;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001377394;rank=2;version=1 17 ensembl_havana five_prime_UTR 81467 81746 . - . Parent=transcript:ENST00000269081 17 ensembl_havana exon 97415 97732 . - . Parent=transcript:ENST00000269081;Name=ENSE00001746322;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001746322;rank=1;version=1 17 ensembl_havana five_prime_UTR 97415 97732 . - . Parent=transcript:ENST00000269081 bcftools-1.21/test/csq/ENST00000269081/stop-gained-not-inframe-insertion.txt000066400000000000000000000021431467060157400260520ustar00rootroot000000000000007210 C CACCTGGAA . 7210 C CACCTGGAA @46862,splice_region|ABCA10|ENST00000269081|protein_coding 8710 G C . 8710 G C @46862 35061 A G . 35061 A G @46862 46859 A G . 46859 A G @46862 46862 AAT A . 46862 AAT A stop_gained&frameshift|ABCA10|ENST00000269081|protein_coding|-|453IYNTQLSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVWSLLKEHKVDRLILFSTQFMDEADILADRKVFLSNGKLKCAGSSLFLKRKWGIGYHLSLHRNEMCDTEKITSLIKQHIPDAKLTTESEEKLVYSLPLEKTNKFPDLYSDLDKCSDQGIRNYAVSVTSLNEVFLNLEGKSAIDEPDFDIGKQEKIHVTRNTGDESEMEQVLCSLPETRKAVSSAALWRRQIYAVATLRFLKLRRERRALLCLLLVLGIAFIPIILEKIMYKVTRETHCWEFSPSMYFLSLEQIPKTPLTSLLIVNNTGSNIEDLVHSLKCQDIVLEIDDFRNRNGSDDPSYNGAIIVSGDQKDYRFSVACNTKKLNCFPVLMGIVSNALMGIFNFTELIQMESTSFSRDDIVLDLGFIDGSIFLLLITNCVSPFIGMSSISDYKKNVQSQLWISGLWPSAYWCGQALVDIPLYFLILFSIHLIYYFIFLGFQLSWELMFVLVVCIIGCAVSLIFLTYVLSFIFRKWRKNNGFWSFGFFIILICVSTIMVSTQYEKLNLILCMIFIPSFTLLGYVMLLIQLDFMRNLDSLDNRINEVNKTILLTTLIPYLQSVIFLFVIRCLEMKYGNEIMNKDPVFRISPRSRETHPNPEEPEEEDEDVQAERVQAANALTAPNLEEEPVITASCLHKEYYETKKSCFSTRKKKIAIRNVSFCVKKGE>453LQYSTL*|7210C>CACCTGGAA+8710G>C+35061A>G+46859A>G+46862AAT>A bcftools-1.21/test/csq/ENST00000269081/stop-gained-not-inframe-insertion.vcf000066400000000000000000000006441467060157400260150ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 17 7210 . C CACCTGGAA . . . 17 8710 . G C . . . 17 35061 . A G . . . 17 46859 . A G . . . 17 46862 . AAT A . . . bcftools-1.21/test/csq/ENST00000271583/000077500000000000000000000000001467060157400166525ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000271583/ENST00000271583.fa000066400000000000000000001113671467060157400210160ustar00rootroot00000000000000>1 1:179851432-179888412 ACAGCCCTCAAGACACACCATGGGCCCAGAGGCAGGTTTGCTACACAGCAGCGACGACGC AGGCGGCGGCCCCAGCGACTCGCAACTGCCTCCCTGACCACAGCGGCCACCGCCCAACAC CCCCGAGAAGCCATCGCCACCACCGGCAGGAGAACCTAGGGTCCATAAAGCCATCTTCGC GATCGACTAAAGCTACGTCAACAACTATGGCGGGCGACGGGCGGCGGGCAGAGGCGGTGC GGGAAGGATGGGGTGTGTACGTCACCCCCAGGGCCCCCATCCGAGAGGGAAGGGGCCGGC TCGCCCCTCAAAATGGCGGCAGCAGCGATGCGCCTGCGTACAGAACTCCTCCGTCGCGCC AGGGCCGGCGGGAAGTGAGGTTCTCGGACGAGCCGCCAGAAGTGTACGGCGACTTCGAGC CCCTGGTGGCCAAAGAAAGGTCCCCGGTGGGAAAACGAACCCGGCTAGAAGAGTTCCGGT CCGATTCTGCGAAAGAGGAAGTGAGAGAAAGCGCGTACTACCTTCGGTCTAGGCAGCGGA GGCAGCCGCGACCCCAGGAAACCGAGGAAATGAAGACGCGAAGGACTACCCGCCTTCAGC AGCAGCACTCAGAGCAGCCTCCGCTACAGCCGTCTCCTGTTATGACCAGGAGAGGGCTGC GGGACTCTCATTCCTCTGAAGGTGAGGACCGCGGAGGTAACAGTCCCAGCCGCGAGCCAG GGAACGCGCGGGGGCGGGCGCGCGCCTCGGTGGAGCTCATGCCCGCCTGGGTACTAAGTA CTGGGATTGGCTAAAGGGTATTCCTCAGCCCCCTCTGGACTTGTGCCGCCGTGCAAGGGC CACCCTGACCCGCAGCGGGGAAGGAAGCGCCGACCGGAGGAGTGGAAAGATGGTCGTGTG GAGCGACCCGGGCAGGGCTGGGGCGCTCTGCCCAACATCGGGCATCAATTTAGGGGAGTC AGAGCTGCCTTTTTCTGCAGGCCTTCACGAGGGGACAGCGAATTACTGCAGGGTCGGTTT CATTTCGGTTCCCTCTACCCTGCGGATGTTTCTACAGAAACCACTTCCATTTCCTTCTTT AACGCTCGCGGGCCAGAGTCCCCAGCTGAGGATCTAACCTTTCAGTCTTTTTCCCTCCTC ACCCAGGTGGGCAGAGAGGAAGGAGAAATTTTGTGAGTGGGCATTTCGAGGGATTGCTGA GTTTAGTGAATTGATTTGAGACCTCACCCAATACTTTCACCGAAATGGGGTAACTCATTT TTCCTGAACTGATGTTCCCCAGTGTTTGATAACTTGAGCTGATTGCTGTTTCTCCAGTGT GGTGGTCCCTGCCAAAAATCTGCCACTTTGGTGGCCGTCACTGTAACCTCAAGTAGTCTG GCAAATCAGACTGACAAAGTAACCTGAAAAACAAGACTATTAATTAGAGTTTTCGTCTAA ATGGACAAAAGGGATGCTGACAAAGTGAGTGTATAGTGTTAGGTAAGTCATAGGTGAATC AGTTTCCTTAATCTATCCTCTCCCACCCTGCCCCCCCCATTTTAGGACCTAACACTGAGT CACAGATGAAGTTTCATGTTAATCCCATGTAAGGCACCTGTGAGGTAAAAATCAGCGGAC CTGAGTCACAATGGGATGACATAGTTTGTGGTAGACTATTGATAGGCGGAGGAGTGGGTT TTCAGCTTAGAGCACGGTGATAGGCTGCAAGTTTACCTGCTGACTCGTGAAGGTACTGAC AGATTTGAAGACTTGATTTTGGAAACTTTATGTTAAAGTTATGTCAGTTATTTTTGGGTG TAGCAACTGAAGACAGTTTAGCCCATATATGTGTTAGTTTTATCTCTTTTAAGATTACAA AGTTTTTGCAGACAAGGAGCCTATAATATATTTGATAGTAATTTAAGTACTTGGTTTAAT TCAGTATTTTTCAGTACCTGGAAGAATGCTTTGTACATGGTAGGCAAAAAATATGTTACA TTGTATTGAGTTCCACAGAGCCTAGTGCAGTTATACAGGCTAACTTTTTTTTAACAAGTA AAGAATTTACCCCTATTTTATTAAATCTTTAAGGATCTAAACATTTTTCACTCTTCTGCT TTCTTCCACATCATTTGTGACTCTCTACCCCATCTTTTTGATTTTCTGAAGTAATATATT TTTGTAAAACAACAATGGCAAATATTATTATATTCTGTTGAATTCATTGTATTCTGTCTC AAGAGGAGTTCTGACTGGTATATTTCCTAAGTTTTGGTAAACCTAACCACCTGTTTCTAA AGAAACGAATTTCTTGAATTTTTGCTTATGTATTGTTACAAAAATGCATAATCTGTGCCA TGATCTCCCAGGTCATATATTCTGAATTTTAACTCTTGTTATGTCTGTTTTTTAGAGGAT GAAGCATCTTCCCAAACTGATTTAAGCCAAACGATCTCAAAGAAAACTGTCAGGAGCATA CAAGAGGCTCCAGGTAAGAATAGTTAACTTTTTGTTTTTCTCCTTACCTACCAACTTTTT AAATGTTCATTGAATTAAACAATGTAAGTATGTGTAAAGAAAAGACAAGGGCAGACACGT GAGTACTCAAGAGTACCAGCCACCCATATAACCTTGTAAGATAGGTATTATACCAATTTC ATAGAAGAGAAAACTGAAACACAGAGAAGCTAAGACAATTCTGTAAGATCACATATGTGA CTGAGCCAAAATTCAAACCCAGGTTTGTCTTCTCCAGAGCCCTTTTACTTTCCCCCCAAG TGCCTCACTATCATTCTCTCATGTCATAACTAGCTACTCAGTAAAATTTGTTCAATGTCA AATGAATGAATATGTTATACTGCCCTGTGTTTAAAATGGATTAACTTTTCTTCATGGTAA AATCTTGACACAGTGTGATCAGTCTTTTCAGTTTAATACTGTGGTTTATCAAATCTTAAG ATGCTATCGACTATAAGAAACACCATCATTGTTTTATGTACCACCTAGCAAGGGAAAATG CTGCCAATTTTTTGGTAATTTGTAGTAATATGCCATAATTATATGATGCATCCCAATTTC AAAGATGTTAAAGTGTTTAAAAAAATTGTCAGAATCAATGTAACATGGAAGTAGGCTACA TTTAATAGTTCACTTAAGTTTTAAAAGCTGATTAAAATATTTTAAAAAGCTGGAGAAGGG ATCAAGTCCAGTTATTAATGCTTTGGGTTTTAGTTCCATTTAATTTTCAATTTGCTTTTT TTGATATTAGGAAAGTCTCACAATAATAAACAATCATAGCTGTTAAAACTGATAATCCTT GGTTTTTAGTACCCAGATCCTGACTTATTTACCTGTTTCTAATAAGATTATGCTTTATAA TGTGAGCTATTGTATTCTAAACTTAGAATAAGTATGTCTGGTTCAAGTTGAGTTTCAAAT AAAAACACCTTCATGCTAATTTTTTTTTCTTTTTTCTTTTTTGAGACAAAGTCTCGCTCT GTTGCTCAGGCTGGAGTGCAGTGGTGCCATCTCCACTCACTGCAACCTCCACCTCCCAGG TTCAAACAATTCTCCTGCCATAGCCTCCTGAGTAGCTGGGATTACAGGCGCCTGACACCA CACCTGGCTAATTTTTGTATTTTTAGTAGACATAGGTTTTCACCATGTTGGCCAAGCTGG TCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTTGGCCTCTCAAAGTGCTGGGATTAT AGGCATCAGCCACCACGCCTGGCCTGTCCTATATTCCTTGAATAGTCTATGTTACTGTGT TAAGATTATAAACTATCTTAGAAAAATGCTTTGAATAATGATGATATAATCAGATTTTCT GGGCCATTTTGGAAAACCATAATCTTGAATTTATTTGCAGTAGATTTTATTGTATACCTG GGAAAGCAAAAATGTCTAATTTTAAATCTAGAGTAATTTATAAAAATTATGGAGTTAAGT AAATTGGTATAATGAAGACTACTGAGTGCTAGCCTCCGGACCATTATAAAACTATTAAGT AATAGAATGTCTTGAATAGTCTTTTTGGAGTTTATATTAGGCTCATATTTAAGAACTGCT AATGAGGTACACCATGGCTGCATGAGGTTGTGGCAAGAGCATTGGACCTCAGTGAAGTTA CTCACTCATCTTGAGCCTTAGGCCTTTACCTGTGTTATTTGCCCTGCATAACTCACAGGG CCTCTGAAGAAATGAGATAGTACATTTGAAATCACTTTGTACCCGGTAAAACATGCAAGT GAGGTTTTTTTTTTCTCATAGCCCTTTACAAGAGATGTGAAGTTCATACAATTTTGCTTA AGTGTATCCTTTTTCTCAAGAAGCTTATGCTATAAATAGAAATTGAAAATGTTTACCAAT ATAAATGACAGATTAAATGGAATCTGCACATAGATTACCTGGACTGTATCAATAGCATAC TGTGCCTTCAGTATTACTAGAAATAAGAGTATGTCTGTCTTTGAGAGGTTTGAGATACTC AGGGTTTTCTTCCTCTAAAAGGTGCTTTTATACTACATCTAATACTTGGCATATTCCCAT CCCATGCCTCTTAATGAAAGGAGAGTTTAGGGAATTATTAAATGCTTATAAAGTCTAAGA GAAATTATTTAAATGGAGTCACTCTTTGATGGAGGACTGCTTTAAGTACAAGTTTAAGGT AAAGATAAGCCCTTCTTCCTCATAGAATGATAGACATTCAGTTTAACTTTGATATTCAAA ATAGTGCTATAATTGTATATAAGGCTACCGGTGTGGTCTGACAGAAAATTATGCAAAGAT GCCCTTACGAATAAAGACCTAGGCCCGGCATGGTGGCTCACGCCTGTAATCCCAGCACTT TGGGAGGCCAAGGTGGGCAGATCACGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATG GTGAAAACCCCATCTCTACTAAAAATACAAAAACTAGCCAGGCGTGGTGGTGGGCACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACGCGGGAGGCGGAGGT TGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGTGATGGAGCCAGAGTCCGTC TAAAAAAAAAAAATACCTAAACCAAAGGACCACCTTATAAAACAACATAGTAAAAATATC TACATCATTTGGTTATCTTGTTATTGGAAGACTTGAAAATGTTGATTAATTCAGAACAGG AATATAGTTTGAAATCTTCTCATTGTTTGAAATTCCATAATTGAGTTGTTTTCACTTAAA ATAGCCGTTAGGTTGTTTAATCAATTCAGGTTATATATACCTACATAACAGTTATTCTCC TATGGCCAGATTCATTTCTTTCTGGAAATTATGACACTAATTTTATAATCCAAAAATATA TTAGGACAAATTCTATTTACTTTTCCAGAAGTTAAATGGGTATTTTTGTTCTACTAGTGT GGTTTCTAGCTAAACAATCAGATAGTTGTTCTTAAATGCTTACTATTTTATCATGAACAT TTGCTTCTCTAGCTGCTGTAGTTAGAGCATTCATTCTCCAGATAATTATTGAGCACCTAC TTTGGGCCAGTCTCCATGCTTTGATTTGAGGGTGCAGTGGTGAACAAAAGCAGACAAGTG AGGAAGCCTCCTACCAAAGAAGGGTACTTGATATTTTGTTCTCTCATACCTCTCTCTGGT ACCCTGTGTCTTTCAAGTACTTTACTTGGCTATGGGATATGTATATAGTAGCACATGCAG GAAATGCTTCTTAAATGAAAAGATGGGAACTGAAGTAGTGATTGATGTCTGTAGAGTCAG TTTGATTAAACATAGCTTAGTAAAAGCAGACAAACCAAAAACAGATTTTAGGTTTTAATT AAACCTGAAAAGGCTAGAAGTATAGAGAAGAAAAAGAGGAAGGTAGTTGTAATATGTGGA GTAACAGGAACTAAAATTTGCCTTTATTATCATGTGTGCAGGGTTTTTGTTTTTGTTTTA AAGAGACAGGGTCTCACTGTCACCCAGGCTGGCGTGCAGTGCAGTTATACTGCAGCCACA AACTCCTGGACTCAAGCTATCATCCTCCTGCCTTCGCCTCCCAAATAGCTGGGATTACAG GCACACACCACTATGCCCAGACAGGGTCTCAGTATGTTGCCTAGGCTGGCAAGATTTATT TTTTAAAGATATCGATATAAGTTCTAAATACTTGATGTGTGAAATACTGAGATAGATATT TCATAGAATTTTAGAGCTGGAATATTTAAGGGGATCATCAAAGTTCCAGAATGTGTTTTT TGCAACTCAGAGCTAAGACATAATGCTTTTTTATACAGATGAATGAAACAAAACATAATA GAATCCAAATTTTGATAAATATTTGGTTTTAGAACATGTTATGTGAGGTACTTGGAGAAA ACATACTTTTATAGGTGGTTTTCTAGACTAAAATTAACATTTTAATAGGATCGGCTTCTC CGCTATCCCTATGCCATTGAACTATAGATGGTCTAAAATAAACCCTGGCCCACATTAATG TTTTTATTTAAAATTAATTTGCATTTCTTCAACACAAGGTTAAATAGAATGAGCGTATTG AATCTCAGGATGTTAACCCTAAAATTAAAATATTCCATAAATAATCCACAATGAGGGTCA GTCACAAATGGAATAGATAATTGAGTTGGTACCATAATACAGATTTTGGTTCTTAATTGA GCAATTTAGAAGAATTTTATTTAGTATTTCTTTCCTTCCTACAGCTACGGTTTGCTGAGA AAAAATGCAAATTTCTCCATCAAGACTATAAATTTTATATGGCAGGAAACTTGTCTCTAG TTCACTATCATCACTAGTTCGCAACAGTTGTCACTTAGAAAGCTTGTCTCTACTTCTCTA GCGTAAATAAAAGCTCTGTAAACCTTTGTTGAATAAATAAGGGATGATCATGTAATAAAG CTAGTATGTTTCACATTTTATATATTTTTAAATGTTTTCTCTTCCTATATTAGCAGTGAG TGAAGATCTTGTAATCAGGTTACGTCGACCCCCTCTAAGATACCCAAGATATGGTAAGAG ATTGTTTGTCTGTTGGTTTACCTTTGTTATAAATACAGTTTTATTTTTAAATATGGTTGT ACATGTATTCATATGATTCAGAACTTAAAAGTTACTGTAAATATACATTAAAAAATCTCC CTGTCCCCTCTGTCATTCAGCCAGCCAGTCTCTCTTCATCAAAAGCAACCAATGTTGTCA GTTTATATTTTTTGGAGATTTACAGAAATTCATGGATGAAATTATCTTGTCCTTTTTATA ATACAAATTTTGGCTTTATAAACTCTCATTTCTGTCTTTTTTTTTTTTTTTAATTTGAGA CAAGATCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAACCAGGGCTGACTGCAGT CTCAATCTCTCTGGCTCAAGCAGTCCTCCTGCCTTAGCCTGCCAAGTAGCTGAGACTATG CATCCACCACCACGCCTGGCTGATTTTTGTATCTTTTGTAGAGATGGGGTTTTGCCATGT TACCCACATGATCTCAAACGCCTGGGTAAGTGATCCACCCACCTCAGCCTCCCAGAGTGC TGGGATTACAGGCATGAGCCACGGCACCTGGCTTACTTTTCTGCACTTTCTTGTTTATTT TTACTTAACATATATACAGAGATATTTCTATATTCATATATAAAAAGCTTCCTTTTTTAA AGAGATTGTTTCTTATATATTCCTGTGATTCTTTATGATGATTTTAAACTATGGTCAGGG ACTTTATTCTTCCAGTATACTGCTAACAAAAAATTCAAGCTGGAGCTCTGTGGCACAGAA CGACAAAATGTCCCTCCCTCAGTTATCTTTTTGACTAAAACGATTAAAAGTATTGCCCTG AAATTGATTTCATGACTATGAAGAAAACTAGTAAAGACACTCCAAGCAGTCTACTTTTAC TTCATTTTCCTTGTTTTTTTGGCTCTTAAAGATGCTTTATCATGGGAACTAAAAAGGAAA TGTATTTATCTTTATATTAGGCTTCTGTACCTTCCCATTCTCTTTATCAAAGAATGATGT TGATTTATTTCGATAGATAGTTGACTATCCTTTTAAGTATTCCAGTGGTAAAGATCTACT AAGGTTTTGTTAATGAACCTGTGGTAAAGAACCATATGATGCATTTCCTTTTCAACCCTA ATCATTCTCTTGCTATGTCTCTTGCAGATTCGACATACAAAACAAATAGAAATACTAAAA TGAGTGAATTATGTTCGTTTATTTCTATTCTTTTTTTTTTCCAGGCAGGGTCTCACTCTC ACCCAGGCTGGAGTGCGGTGGCGTGATCTTGGCTCACTGCAGCCTCCTCCTCCTATTGTA GTCCCAGCTACTCTGGAGGCTCAACTGAGCCTCCTACTTCAGCCTCTGGAGTAGCTGGAA CTACAGTCATGCATCACCATGCCTGGCTGATTCCTGTGTTTTTTATAGAGATGGGGTTTC ACCATGTTGCCCAGGCTAGTCTCGAATTCCTGGGCTCTAGCAATCCACCCGCTTTGGCCT CCCAAAGTGCTGGGATTATTGGCATGCACAACTGCGCCCAACCCTATCTCTAATTCTTAC AAGGTCTCTTTGAGGGTCCAGATTAATAGAATACAAGAGTATATATATCTAGTCATTGGC TTGAGAATACTAATTTATTATGTCAGTTTGTGGGGACCCAGTCCCTATGACTAGGACCTC CCATAAACAGCCTTGGTTTTTGTTGTCTATAATTATGCCTATATTATTGCTTAAATTCAT ATAAAAACATGTAATCAATTTAGTCCTGCTAGTCTTCATTAAATTCACACTATTAGGAAA AAGGAGATAACAACTTACCAATTAAGGTTTTTCTCTTGATTTATTTTTTGTTTTTGTTTT TCTGAGACAGAGCCTTGCTCTGTCACCCAGGCTGTAGTACCGTGGTGCGATCTCGGCTCA CTGCAACGTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGG GATTACAGGTGCCCACCACCACGCCCAGCTACTTGTTTTGTATTTTTAGTAGAGACAGGG TTTCACCATGTTGGCCAGGCTGGTTTCAAACTCCCTGACCTTGTGATCTACCCCACTTGG CCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCCGGCCTTTCTCCTTGATTT TTATTTTTATTTTTTATTTTTATTTATTTATTTATTTTTATTTTCTCGAGACAGGCTCTT GCTCTATCACCGAGGCTGGAGTGCAATGGCGTGATCTTGGCCCACTGCAACTTCTGCCTC CCTGGTTCAAGTGATTCTCCTGCCTCAGCCTTTCAAGCAGCTGGGATTACAGATGACCAC CATGACACCCAGCTAATTTTTGTATATTTAGTAGAGATGGGGTTTCACCATGTTGGTCAG GCTGGTCTCGAACTCCTGACCTCAAGCAATCCACCTGCCTCGGCCTCCCAGAGTTTTGGG ATTGTAGGCGTGAGCCACCACACCTGGCCCTTTCTTCATTTAGAAAGTGAATTCGATACG TTGTTCACGGCGAGTTCAGTGTCCTTTGCTGTAATACGTTCGTTGAACGGGTTTTAATTC ATTTCAGTGTCTGCCTGGCTATAGGACATGACATACCATGATTTGTGGTTTTAAATGAAT CTACATTGAATGTTGTTAGACTTAGTTTTTTTTACATTTTAATTATTTTCTAAATTTGAA GATGAGCCAAAAGGGAAACGCTTCATTTTTCTTTATAAATCATTGTACCTTCCTCTAATT CATCTTTCACTTAAGTTCAGGCCACTTCTTTAGAGACTTAAAAAAGCTTTTTAGGCTGGG TGTGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACCTG AGGTCAGGAGTTCAAGACCAGCCTGGCTGGCATGGCAAAACCCCGTCTCTACTAAAAGTA CAAAATTAGCCAGGCGTGGTGGTGCTGTGCACTGTAACCCCAGCTGCTTGAGAGTCTGAG GCAGGAGAATCACTTATACCCAGGATGCAGAGGTTGCAGTGAGCCGCAATCACGCCATTG CACTCCAGCCTGGGCAAAAAGAGTAAAACTCTGTCTCAAACAAAAAAAAAAACTTCTTTG GGAGGCCAAGGCGGGCAGATCACAAGGTCAGGAGATCGAGATCATCCTGGCTAACATGGT GAAACCCCGTCTCTACTAAAAAGTACAAAAAATTAGCCGGGCATCGTGGCGGGTGCCTGT AGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAAGTTGGGAGGTGGTGCTT GCAGTGAGCCAGGATTGCGCCACTGCACTCCAGCCTGGGGGACAGAGCGAGACTCCGTCT CAAAAAAAAAAAAAAAAACTTTTTAAAAAAGAGAACTTGGAACTGAAATAACCTAACACT CTTTGCTAGAGCATTTTTATAAGCACCTTGTAATAAAAACTTTGTTTTTTATTGTCTGAA ATTATGTCATATTATTTAAATTCATTTTTTTGTGTGATTGTAAATTTAAAAAAGAGATTT TCATTTTAAAGTAATTTTCTGTGGGTTTAGTAGAAAGAATGAGGCTGGGTGCGGTGGCCC ATGCCTATAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGT TTGAGACCAGCCCGGCCAACATAGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAG TCGGGCATGGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGGAGAAT TGCCTGAACCGGGGAGGTGGAGGTTGCAGTGAGCCGAGATTGCGCCATTGCACTGCAGCC TGGGCGACAGAGCGAGATTTGGTCTCCAAAAACAAACAAACAAACAAACAAAAAAAAAAA AGTGACATTTTTCAATTCCTTTATAGTAATGTTAGTACACCTTGGAGTTTATGAAATGGC CATTCGTGGAGCTTGAATACTAGTGATACCACCAGACTATTCTTTGCTCTTTCCTGCTGC CCCACTCTTGACTCTGTTCTCAAAAGCGTGATTGGCATCAAATAGTCTTTTTTTTCTTTT TTGAGACAGAGTCTCAATCTGTCACCCACGCTGGACTGTAGTGGTGCGATCTCAGCTCAC TGCAACCTCCACCTCCCAGGCTTAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGG ATTACAGGCACATGACACCATGCCTGGCTAATTTTTGTATTTTTAGCAGAGGCAGCATTT CACCATGTTTGCCAGGTTGGTCCTGAACTCCTGACCTCAAATGATCCACCTTCCTTGGCC TCCCAAAGTGCTGGGATTTACAGGCATGAGCCACCATGCCCAGCAGATAGTCTTAAAACT ATCTGTACCAGGGGTTAGCAAGCTACCGCTTCTGGGTGAAATTGGCCTACAATCTTTTTA ATCAGCCCATGAACTAAGAAGGAATTTTTACACTGCTGAAAAAGACAAAGCATGTAACAG AGACCTTATGTGACTCACAAAGCTTAAAATATCTACTATTTAGTCCTTTATAAAAAAAGT TTGCTGACCCCTGATTTATACTGATGGCAAGAATAAAGACAACAAGGCCGGGCACGGTGG CTCACACCTGTAATCCCAGCACTTTGGGAGGCAGAGGCGGGCGGATCACGAGGTCAGGAG ATTGAGACCATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAGTAGCTGGGCGCAGT GGCGGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCG GAAGGCAGAGCTTGCAGTGAGCCGAGATCCCGCCACCGCACTCCAGCCTGGGCGACAGAG CGAGACTCTGTCTCAAAAAAAAAAAAAAAAGAATAAAGACGACAAATCACGCAAATGGTC ATTTGTTTGTTGTCAGAGTAAATTCAGGAGTTATATACTTGCTCGAACATATATTTATTA CAACACTCCATACTAGGTTGTACCCAGAGCACAAGAAGAAAGGAAACAAGCTGGGCCTGG TGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGACGGATCACCTGAGGTC AGGAGTTCAAGACTAGCCTGGCCAACATGGTGAAACCCTATCTCTACTAAAATTACAAAA AATTAGCCAATTGTGGTGGCAGGCACCTGTAATCCCAGCCACTTGGGAGGCAGGCAGGAG AATCGCTTGAACCTGGGAGGTGGAGGTTGTAGTGAGCCGAGATCGTGCCATCGCACTCCA CTGTCGGCAACAAGAGCAAGACTCCATCTCAAAAAAAAAAAGAAAGGAAGGAAGCAATGA CTCCTGTGTTCTATCCAGTATTCCTTTGAGAAAGCACAGTAGTCTTATTTATATTTTCAT GTCTTTGTCCCCAGACAAAACACAAAGTAAGCCAAGTTTATGTTTTCTTGAGTGGCCTTT GCTCCTCACACCAAGTACCTCCCACAAATTTCTAGGAATAGCAAAATCTACAGGAGAAAT GTAGATGCTTTGGCACCTGGGCTTTCAAAATAACTAGGGAATTTTATAAGTTGTAAAAGG CCGGGTTATACCTAAGGTTTGAATTCCTTAAAAACTGGCCAAGTAAAAGAAAGTAAACAA AGTGGCACAATTAATGCTTGGTTTTCACTAGAGGCGATGACTGTTAAGTGATCTATCTTA AACATAAAGACCTCGGACTTCTGAAAGTAGCTTTTCCTAATTGGTTGAGGTTACTGGAAA ATATAACACCTTCTTAAACAGCATGTTTAATTATTACCATTTGTCTATATATTTGCTAAA GCCACAGCCTTTATGATTTCTTTAATAATGTTTTAATATTAAGGATTTTTTGCTCAAAAT ATGATTTTAATTCTCAAAGCTTCTGTATGAACATTGGGAAGAGTAATACCTTTTTTAAAA AAGTATTTTTTTAAGGCCAGGCATGGTGGCTCATGCTTGTAATCCTAGCTGTTTGGGAGG CCAAGGCAGGTGGATCGCTTGAACCCAGGAATTTAGCCTGGGCAATGTGGCGAAACCTCG TCTCTACAAAAAAATGCAACTGTTAGCTGGGTGTGGTGGCACGTGCCTATATTCCCAGTT ACTTGGGAGGCTGAGTCTGGAGGATCACTTGAACCCAAGACACAGAGGTTTCAGTGAGCA GAGATTGTGCCACTGCACTCCAGCCTAGGCGACAAAAAGAGACCTTGTCTCAGAAAAAAG AGGCCGGGCACGGTGTCTCACACCTGTAATCCCAGCACTTCGGGAGGCCGAAGCAGGTGG ATCACCTGAGATCAGGAGTTCAAGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTAC TAAAAATACAAAAATTAGCCGGGCATGGTGGCACAAGCCTGTAGTCCCAGCTACTCGGGA AACTGAGGCAGGAGAATCACTTGAACCCGGGAGAATCACTTGAACCCGGGAGGCAGAGGT TGCAGTGAGCCGACATTGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTC TCAAAAAAAAAAACAAAAACAAAAAACAAAATCTAATGCTTTAACTTTCGACATGTAGCA GCCAAGTTTAAAATAGAGGTAGGTGAAAAACAAAAGAGGGAAATGAAATTAAAGCTTATG TAGTCATGGCTACTGATTCATCATCAGATCGCACTTAAATATTTATTTCCATTCTTTGCA GCTTGGGTAAAAAGGTGGAATGTTTAAAACCTTGCAGGTATCTAATTATTAAGCACTAAT TTCAGACTTTTTAAGTTGCTAAGTAACGTTAATCATAGTATGAGAAATATTAGCAAAAAT CTGGACTTAACATCTTTATTCTATAATCATAAAATCTATTTTATTCATGGAACAAACTTT TTTTATTTTTATTTTTTTTGAGACAGGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGGA GCGTGATCTCGGCTCACTGCAACCTCCGCCTCAAAGTGCTGGGATTACAAGGCATGAGCC ACCATGCCCAGCCAAACATTTTTAAACACCTTCTTTATGTCAGTGACCGACCTAAGTGCT AGGATCATAAATAGCCATTCAGGTTTTTTTTTTTTCCTACCTCTTAGATGTACGTGATGT AATGGAAGAGAAAAACAAGTTTACAAATCTTTTTTTTTTTTAAGTGCTGAAATAGTGACA TATGTCTGCGGGATCCTAGACGAGAAGCACCCTACTCAGTGGAAGAGGTTGAGGCGGTTT TATGAGTTGGAAATGACATTTGGATTGAATTTTGAGGGATGAATAGCAGGCAGAATGAGG ACGGAGACTTGCAAATACTACAGTTTGCTTTATAATAGACATTTTACCTTTAGAGAGCAT GCAATATGAGAAATTAAAGTCTTTTATATTACAGACAATACTCTCACACTAGCCATAATT CTTTATCTGAGACGTTAAATAATGTTTAGAATGACATTCGAAATCATAGCAGGCTTGGGT TTCTTGAGCTTTGTTTACCAGAATGAAAACCTTGTTTTAAAATGTATCTGTAGCCAAGAC AGTAGATAACCTGATTCAATAATGATTGATTGTCAAATCTACGGGGATTATTATTATTTA AGATCTAATTCATAGATATTATTGGATTATAAAACACAAAATAGTACTTTTTTTGTTTTT AGTGATGGGATCAAGATAGCATTGCATAACTAGTTATTCTTGTTTTGAATACTATTGATA AATATTTATTGTTAGGAACATAGAATTCTAAAAAAGGATCTTTAGTCACTAGATTAAATC CAGAAGTCTGAAAAGTGTTGAAAAATGGATAGAATCCATGATTTATTAGATACTTCAAAT ATAATAACATGTTAGAAGTATTAAAATCAAATGGGGAGCTCCCTTATGTAAGCTGGCTAA AAAATAATTATTAAACCATCTCTCCATGCTAATTAGATAACACATAGATAAGCAGAAAAA AGATTGAATTTTAGGCAACTTGGTATATGGAGAAATGACTGTTAAATGAATTGGCTCTAG ACAAATTGACCTGGAACTTCAAATGTGTACAGAAATAAAACATATCTTCAAATGTATACA GATAAAACATACCTATCGAAAAAAGGGATTACTGTATTAGTCATACTACTGTACTGTGTA CTGTACTGTACTATTCTGATAGCTCAACAAATGAATGTAAATCTCCAACATATCCTTTCC ATTATTATAGATTCTAAAATCTATTCAGCCCTAGTTAAAGAGGTTTTGTCTACCATATAA TTTTTAGAGTAACTATGTAAAACATAACACTGAAATATAAATGGGACCTTAGTAAAGCCT ACTGTATTACATGAATTACACTTAGAAGTTTATTGGAACCTCTCATATTAGGAAAAGTTC AGCTGTCAGCCGTTTCTTTATTCATCTATTCAAAAAATTGGCCAAGTGCAGTGGCTCATA CCTGTAATGCCAGCACTTTGGGAGGCTGAGGCAGGCAGATTACTTGAGCTCAAGAGTTCG AGACCAGCCTGGGCAACATGGCAAACAAAACCTTGTCTCTACAAAAAGTATAAATATTAG CAGGGTGTGGTGACATGTGCCTGTAGTCCCAACTACTCAGGAGGCTGAGGTGGAAGGATG GCTTGAGCCTGGGAGGGAGGGGTTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCT GGACGACAGAACCAAACCATGTCTCAAAAAAAAAAAAATTATTGAGTGTTTACTATGTGC TGTTATGAACAAGACTGATGAGGTGGTAGGATTGTAATAGACTGGAAGTCAGAAGAACCT GCGGTCTTCTGGCTTTTTTTATTATTAAATTAGACCTATACCCTTAGACAAGTCACTTGA TATCTATGAACCTTACTTATGAAAATCTTCCCTTATGATGAGATGGGAATCAGATGACAT TCATGAAGGGTTTTTTGAAAATCAAATAGCATCATGCAAATATTAAGGACTTAGCATTTT AAGATAATAACAAAAATATGATTATTGATTCTTAAGAAAGCATCTTGTATTTGCATGCTA TGTGAATAGTTACATAAATGAATAAAGTAAAACTGCTATACAAAAATATGAAGTACTATA ATAATTATGCACTTAGATAATAAAACTTCAAAAAGAGAACAATACCTTTTTGTAGGAATG GAAATATTAATTAAAAATTTTTGGCCAGCTGTGGAGCTCATGCCTGTATTACAGTCTCAG TACTTTAAGAGACCAAAGTGCTGGGATTACAGGCTAGGAGATGGGAGGATTGCTTGAGGC CAGGAGTTTGAGACCAGCCTGGTCATGATGTAAAACCCCATCTCTTGTTTTAAATTAAAA TCTTAAAAAAAATTTTTTTCGTTTGACTTTTCCTTTTTCTCCCTCAAAAAAGAGAAAAAG AAAGGACAGTGTTCCTAAGAAACCTAGAGCAAAATAGTACTTAATACACCAGAGTCTAGC TCTTTAAGAGTAACATGGTGTTATCAGCAGTTTTCTCTGGGTTAGTTTTTTTTTTTAAAT AAAAAAATGTTGGCAAATATATTTCAGATACTGATTTGCACTTGCCACTGTCAAGAGGAA GTATTTTCAGTGGAACTCAAAGCTTGACTAGTATTATACTAATCTAATTAAATGGATTTA AAATAAATATTTTCAAATTCACCGTATAATGTGTTAGCAGTTGCTTTCTATAATACTATT GTCCCTTTTAATAAGCAAATTGAGGTTAAAATCAGTAGAGATAAAAGCTGAAATTTTCTC AGCTTTGTTGAAGAAGTCTAAATCATGCTACTTCTCTACATATGATCCTTCAGCGATATT TTAACCCAATTGTGAAATACCTGCATTTGGGTACATCTCACTATTTTTTTTTTTTTTAAG TTTCAGAATAGCCCATGTAAAAATACTATGTTCCAAGTTTATTTGATGTGTTTTGCTTGT TTATTTTTGTTCAAATTCTCTTTTGCACTGGAAAACAGTGACATACATGGACCCGCCAGA ACTAGAAGTTTCTTTACCTTTCTTCCTCTTTGGATACACCAATGCTCGAAAGAACTGGGT TATCAGTCCAGTTAGTGTAGTTGGTTTTTAAAGGGAGTATAGGGGATTTGGCAAATAAGA GAATGAGAATATAGCAAACCTATACACACTAGAATATTTGTCAATGTAGAATTTAATGTT TTTTTTGCATACAAAGGTTACATTTTAGAGTAAAAATAGACCTGTGACTGAAGGAAAATT AAACACTTCATTTCCTTTTTCTGTTTGAGACAGAGTCTTGCTCTGTCGCCCAGGCTGGTA TACAGTGGCGCGATCTCGGCTCACTGCAACCTCTGCTTCCCAGGTTCAAACTATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACACACCACCACTCCTGGCTGATTTTT GTATTTTTAGTGGAGACAGGGTTTCACCATGTTGACCAGGCTGGTCTCAAACTCCTGACC TCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCCGGGATTATAGGCGTGAGCCACTGC ACCCGGCCAATTCTTAGTGATTTAACAGAAAAAGAATTTATTTAATGTGTCCTCATGTTC ATTTTCCTAAACGAGATGCTCTTTTATTTATTCCTAAGCTTTAACTTTTTTCCTAAGCTT TTGTTTATTCCTAAGCTTTAACTTTTGATGTTATATGTTTAATATTTGATGTATGCTTTT TTCTTCTAGAAGCCACCAGTGTCCAACAGAAGGTCAATTTCTCTGAAGAAGGTATTTTAC TTGTAAATATCATATAATATATACTTTAAGTCTTTTTCTTTACATTAGAAGCCATTCTGA TAGATATTTAAGAAGTGGGAACAGAGCCGGGGACTGTGGCACATGCCTGTAGTCTCAGCT ACTCGGGAGGCTGAGGCAGGAAGATCACTTAAGTCCAGGAGTTCTGGGCTGTCTGTAGTG CACTATGCCGATCAGGTGTCTGCACTAAGTTTGGCTTCAATATGGTGACCTCCCGGGAGC GGGGGACCACCATGTTGCCTAAAGAGGGGTGAATCCATTCAGTTCAGAAACGGACCAGGT CAAAACTCCCGTGCTGATCAGTAGTGGGATTGCAACTGTGAATGGCCACTGCACTCCAGC CTGGGCAACCTAGTGAGAGCCCATCTCTTAAAAAAAAAAAAAACAAAAAGAAGTTAGAAC AGAAAATAATGTGTTTTTCTTCAAGAAAAAAAATTCATGCTTATCTGAACTGTTAACTGG GCAGAAATAATAGGACAGATAGAATGAGTGATGACAGCCTTACATTTTAAGCATCTTTTG TCTATTTGGGTTCATTTTAAGCAAAGATAATATTTTCTATTATGGTATTAAAGTAATCAG TTTTCCAAATTCTCATAACCAGTTTATGTTTGAAAAGTACAGGAATAAAATTTAGTTTTT GTTGAAGCTCAGCATAATCTGAGGGTGGTCACCTGCATAATAGAATGTTTGTGTGCAGGT GTGTGTACACTACCCCTCTACCACCAACACACACACACAAATACACATCTGAATTTAACT ACACACTAATTATATGTAGTTTTCCTCCCCATAAACTTTTTCCACTGTTTAACGCTCATC TGTTCATTTTTGACTCTACATTAAAGCCTTATAGTTTTTTAGATATTACTCTGAATATTT GTTTAGGAAAGTATTATGTGCCCCAGAGGACACAAATTGAGATAAATTTTAGTTCCTTTG GAACTTTGGGATTCAAAATAATAAGCATGATAAACAAACAGTAGTTCTATATCTGATAAC TTAAAAGGCTTCTTTTAATGTTAAATTATTTGCTTGGTTTTTTTAAATTCAGATCTTCTG AGCATTAAAATAGACTATATTAGTATATTGTTTACTTCTCTTTAGGAGAAACTGAAGAAG ATGATCAAGACAGCTCTCACAGCAGTGTCACTACTGTTAAGGCCAGATCCAGGGATTCTG ATGAATCTGGAGGTAATATTGCTTTATATACATATGACTCTTCTCATAGAACTATCTTTG GTATTCCATGAATTTGCTTTTTAAAAAAAACTTTCAAATTTTTATTAATACTTTATAAAA AGTCGTGAATTTTTCTTTAAATATTTATTAAAATTACTGATTTCGTGTTCATCCGATTAA TACTATGTCATGATATCTAAACAAATCACTTTTAGCTTTTTTTGATATTTGTGGAAAATA AGATATTTTTGTGCTCAAAAGAAGAGTTACTTGTTGTTTTTTGAATTTTATAGAGAAACT AATCACATTGCCATTGGGACTGACAACACTATCTGGAGTGTTACTTTTAGGAAGTTTTCA TTTAATTATATAACTAGCTTTATCTCTGGATTTTCAAATTCAAACCAAATTATTAATTAA CAAGTTCTGATTGTTTATGTGAATTTAAGTTTATTCAATGAAAGAGTTGACTAAAGAGAG AAAAATACCAGTTTGAGGCTTAAGATAATGTTGAACAAGACCCTCCCCCCCAAAAAAGAT AATGCTAAACAAATTTGTAAACTCTGTAAATAATGAGTAATTTTATACTTTAGTCCTGCA CTTTCCCTTCACCACCTCCTTAAAATTTCTGTAATTCCAATTCTTTTTTTTTTTTTTTTT TTTTTTTAAGGCAGAGTCTCACTCTGTCACCCATGCTGGAGTGCAGTGGCGCAATGTCGG CTCACTGCAGCCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCCCCCAAGCAG GTGGGATTACAGGTGCGCACCACCACATCTGGCTAATTTTTGTATTTTTAATAGAGATGA GATTTCACCATGTTGGCCAGGCTGGTCTTAAACTCCTGACCTCAGGTGATCCACCTGCCT CTGCCTCCCAAAGTGCTGAGATTACAGGCCTGAGCCACGACGCCTGACCTGTAATTCCTA TTCTTTACCTCATCATTTCACTTTAAAAATAAGTACATAAGCTGGTTTGGTTTTTGTTTT TATTTTTTTGAGACAGGATCTCTCTCTGTCACCCAGGTTTGAGTGCAGTGATGCGATCAT GGCTCACTGCAGCCTCGACCTCCCAGGCTTAAGCAATTCTCCTGCCTCAGCCTCCCAAAG TGCTGAGATTATAGGTGTGGGCCACCGTGCCTGGCATTATACGCTGGTTGTTGGGCATTT GGTATTCTGTGTGTTTCCCACCCTTCCTCATTTTTCCTATGAATTCTTGATACAGAAATG GAGATTTGTAACACGCTGGTAGTGTCTAGCTAGAATTTCTGGGTTCCATTCCTTCACTTT TTAGCTGTTTGCCTTTAGAGAGTTATTTAACTTCTGTGTTCCTCAGTCTTGTCATCTGGA TTGTTGTGGGGGTTAAATTAATTCATATATGCAAAGCACTTACCTGGCACATAGTAAACA CTAAGTGCTGTTATTAGTGTTCATACATATTACATGAAGCTCTAAAAATTAGAGGTTAAT TAAGCCATTTATATAGCCAATAGTTTGCTGCCATTGCTACCAGCATAACTATTTGGAAGT ACATAAACCTCAGGTCCTGTGATTGCGCGATCGCACTTCAGCCTGGGCAACAGAGCGAGA CTCCATCTCAAAAAAAAAAAAAATATGGGCACTTCACCTTTTTGTATCAATGTGTCTGTT TCCAAAACAGCAACCTGATCACTTTTAAACTAATTTAGTTATAAATTCTACTTTTATTTG GGAAAAAATGTTTTTAAGAAGAGTAGACTGAAAGCAAGGCATGGTGATAGGTACCTATAG TCCCAGATACTGAGGAGGCTGAGGCAGGAGGATCCCTTCAGTTCATGACCAGCCTGGGCA GTAACGTGAGACTCCATCTCTTAAAAAAAAAGAAGAAGAAGAAAGAAAGAAAAAGAGTAT ACAAAAATATTGCCCACTTGCAATAAAAATTTAAAGCAAAAATGGATATTAATGATTTCA AGATGCTCCACTGTTGTAAACTTTGAAAATTTTCCGCAACTCAAAGGTTTTATTATGTCA TTACCTTGGGGCATGTTCTGTATCATAACAATTTTTTAAGTGGTTATTAGCTAATATTTT AGATGTGACATGACTCTTTAGAAACTTTTTTAACCTTTTTTTTTTTTTTGAGACAGAGTC TCACTCTCTTGTTCAGGCTGGAGTACAGTGGTGCGATCTCGGCTCGCTGCACCTCTGTCT CCCTGGTTCAAGCAGTTCTCCTGCCCTAAGGCCTCCCGAGTAGCTTGGATTACAGGCACG CGCCACCACGCCCAGATAATTTTTGTATTTTTAGTGGAGACGGGGTTTCACCACGTTGGC CAGGATGGTCTCAATCTCCTGACCTCAGGTGATCCGCTTGCCTCAGCCTCCCAATGTGCT GGGATTATAGGCAAGAGCCACTGCACCCAGCCTAGAAATTTTTTAAATAAATTATGCATC CACGTTTTTAACCACCTGGGAGTTACCCGAATATTTTTGCTCTTTTTATTAATTTCTCAC TGTTGTCTTGTAAAATGTACAGTCTAAAAGTTGGATATTATTTATAGTGTACTGTTTTTT ATTTTTTAGATAAAACCACCAGATCATCTAGTCAATATATAGAATCATTTTGGCAGTCAT CACAAAGTAAGTAAAGCTGTGTTTACAGTGTCTTCCTGTGAGCTTGGTCAAATGATGTTC CTATTTTTGAAGATCCTCTTTTGAAATTTAACGTAAATATTGAACAAGAGGAATAATGAA TGCTAAAAAAAAACTTATCCGATATCTCTCTACCACTTGACCTTGCTTATTGAGTTATTA TTCTCTATACCCAAACCTGAATTTGAACTTAAAAAACAAACAAAAAACTACTACTTCCTG TGATTTGTTGAATGTCTTTGCTAGCAGTATAAATGGGTTGATTGCTTTTATTTTAACAGA CTAATGTAGTAGTTTGAGCCTATTTATATGCACTTATTCTAATAAGGACATAAAATTTTA TATTAGTACAATTTCAACTCTGTTGTAAAAGTTTGGAAGGATGAATAAATAAGTGATAAA GCACATGTAATAAAAAGTTAATGGCAAGCTTGGTTATGGGTATATAAATATTCATTTCAG TCTTACAACTGAAAATTTTTGTGATCAAATATTGAGAAAGTATAACAAAAAAAGATTGGA AAGTCATATACCAAAATGCTAATAATGATTTGCTTAAGAATCATTGGTGACATTTTTTTA ACTTTATTATTTTCTTTTTTCTTTTTTTGAGACAGGTTTTCACTCTGTTACCCAGGCAAG TGTAGTGGTGCCGTCATGGTTCACTGTAGCCTCGAACTCCTGGGCTCAAGGGATCCTCCT GCCTCAGTTTCCTGAGTAGCTAAGACTACAGGCACGTGCTACCATGCCCAGCTAATTTTT AAATTTTTTGTAGAGACAGAGTCTCACTATCTTGCTCAGGCTGGTCTCAAACTTTTGGGC ACAAGCATTCCTCCCACATCAGCCTCCCAAAATGCTGGGATTGCAGGTGTGAACCATTGC GCCCAGCCACCTTTATTATTTTGTTACTACTGTTTTTTTCTTTTGACATTTTTAAATCAA GTCTCCCAAAATCTGAGTTAGTTATTAATCAACCAAAAATATCTTTGTATGTAAAAATCT TCAAGAACTTTTTTTTTCTTCCACATTACTTTCTTTTCTTAAGAAAAAACTTTTGGAAGG CCAGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACCAAGGCAGGCGGATC ACTAGGTCAAGAGACCGAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAA ATATAAAAATTAGCTGGGCGTGGTGGCGCGTGCCTGTAGTCCCAGCTACTCGGGAGGCTG AGGCAGAAGAATGGCGTGAACCTGAGGGGGCAGTGCGGAGCTTGCCGTGAGCCGAGATTG TGTCACTGCACTCCAGCCTGGGCGACAGAGTGAGACCCTGTCTCAAGAAAAAAGAAAAAA AGAAAAAGCCTTTGGAAATCTTTTTTAAAATCATTGTATTTCTAGAATTCAATTTTATAT TTTTTATTTTAATTTTTAATAGGTTCTGGGTTTGTGACTATAAAATGAGACATAAAATGA ATTAGCTGCTGGGAAAAAATCAGTTGTGGAAAATTACTCTTCGAATTATTTTATGTATTT GCCCTATTTTACTCCAAATCTTTGATCTTTGGAAACTCTTAAATGTATCTACCCGTATAA ATGATATTATACCCATGCAGTGAGATACTATTTAGTCTGGGGACGGTGGCTCACACCTGT AATCCCAGCACTGTGGGAGGCCAAGGCAGGTGGATCACTTGAGGCCAGGAGTTTGAGACC AGCCTGGCCAACATGGTGAAACCCCGTCTCTGCTAAAAATACAAAAATTAACCACGTATG GTGATAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACC CAACAGGCAACGGCGGCAGTGAACTGGGATTGCACCACTGCACTCCAGCCTGGGTGACAG GGCAAGACTCCATCTCAAAAAAAAAGAAATACTATTTAGAAATGAAAAATGAGTTAGTTC ATTGTATCCTAATGAAAAGTTGATCAAGATATATTTCATTGACTTTAAGATACTATTGAT TTTATGTATCAATGAGAAAGAAAAACCATCCAGTTAAACTATGCCATACCATTAATTAAA AGATATATCTGTAGATCAAAGGGCATTTTTTAAAAAGTATGTCTTAGAATTTGATGAAAA TATTAAAACGTATGTATCCACTTTTTTAAAAGTATATTTTTAGTATAGGCTGAAAACAAA GCTGAGAGAATATCTGTCTTATTTACCATAATATTTCTATGTTCAATGTTTTGCACATAG TAGATACTTAACAGATAGATATTCATGAATTTTTAAATTAAGCATTTCTAGAATGGCCCC TTTTTTTAAACAGCTAGCACATGTTTGTATTCAGAAAAAGTTGAAAATAAATAAATGTAA ATCGATACTTGTATTTATCATCAAAGAGTAACTCATTTTCTCAGGGCAGATTTGAAAATT TACCTTGTTATAATTGTAATGTCATTTTTTAGTCATCCCATTGTGTCATTTTACAGTTAT CCTTAAATACCACCTCAAAACCTGAAGTAGCATGTTTTACTTCATAGCTACTTTGCAATG TCCATAAATCTGCATAGATAGTACATACCATTTCTTTATGGTATGGTATGTGGTATATGA TATGGACTGCCTGGATTTGTATCTCAGCCCAACTACTTTTAGATATATAATTTTGGAAAA ATTACCAATTTTGGTTCCCCCCCCCCCTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTC GCCCAGGCAGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAAGCTCCGCCTCCCAGGTTC ACGCCCTTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCACGC CTGGCTAATTTTTTATATATTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTC TCGATCTCCTGACCTCATGATCCACCTGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGC ATGAGCCACCGCATCCAGCTGATTTTCCCTTATTTATAAAATACGAACAGTAATAGCATC TACCACATAAGAATTAAGCAAAATTGGCTGGGCATGGTGGCTCATGCCTGTAATCCCAGC ACTTTGGGAGGGCGAGGCAGGCAGAGCATTTGAGGTCAGGAATTTGAGACCAGCCTGGCC AACATGGTGAAACCCTGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGGGAAACCCTG TCTCTACTAAAAAGACAAAAAATTTGGTCAGGCATGGTGGTGCACACCTGTAATCCCAAG TACTTGGGAAGGTGAGGCAGGAGAATATCTTGAACCTGGGAAGCGGAGGTTGCAGTGAGC TGAGATTGTGCCACTGCATTCCAGCCTGGGTGACAGAGTCAGACCCTGTCTCAAAAAAAA AAAAAAAAAAAGAATTAAACAAAATTATACTTGATATATATGACTATATGTAGTTTTTAT TTTGATGGTACTGATCCTAAACTAACTCCTTATTGTTGCCCAATTCCTAAACATTTTGAA GTTTAGAAATGAGGGGGAAAGAAATACACACACACTTTATATATATATATATATATATAT ATGTATATATATGTATATATATAGTATATGTATGTTTTTTATATATATATACTTTATATA TTTATATGCTTGGAATTGATGAGAGAATGTTTTTTGTCTGTTGTTTGTTTTTAGTATCCA CAGTAAACAAGCAAAATGTCTGTGCAACATCTTTTTTGTTGTTATTTTCAAGTATTCTAT GACCTTATCCCTGTTTTCTGTTTCAGGTCAAAACTTCACAGCTCATGATAAGCAACCTTC AGTGCTAAGTAAGTAGTTGGTTGTCTGCTCTTTTTTCAGCCAATCAATTCTTTTCTCTTT TTTTTTTTTTTTTTTTTTGAGACGATGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAATCT GGGCTCATTGCAAGCTCCACCTCCTGGGTTCACGCGATTCTCCTGCCTCCGCCTCCCAAG TAGCTGGGACTACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAG ACGGTGTTTCACTGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCATGATCCACCTGC CTCGGCCTCCCAAAGTGCTGGAATTACAGGTGTGAGCCACCGCACCCAGCCTCAGTCAAT CAATTCTAACCTTGCCTTATTCTCCCAACAAAAGTTGTAATAAGATTTTAAGTCATTTTA CCCCTCTTTACCTTTTTAATTCACCACGGATTGGTACTACCTATAATAATTACTCTGTGA TATGGAAATGTGTTCAGGGCTATTTTACCACAAGTAATTTGTATTATGTGATAATATATT TATTTGCTACCTGCTTTGCTGTAGGAAGTGGTTCATCCTCACTGATACGATCCTTTGAAA TTATCTTTTACTTATAAAACTATTGCTTTTATTGTTTTCTTCCCCTACTTTATTTTGTCT TTCTGATAGATTAATTTTATAACACTGGAATATGGTATAAACTTTCAAAGTATGGGAAAT TATCTTTTGATATATGTATTTGCTTCAGGCTCAGGATATCAAAAAACTCCCCAGGAATGG GCCCCACAAACTGCAAGAATAAGGACCAGGATGCAAAGTAAGTAGATAAATCTCTGTTAT TGAAATAATCTTGTGTATTTGCTATGTTTTTCTTGACAAAAATATTTAGTTCTTCAGATA AACATTTAGGTTGTTTGTGATTTCACTAATAAAGTACAGCTATGATTACTAGTTTAGTAA TTTCTTGGACTGGCAGCACATGGGCTGGGTGTAGAATGTAAATAGTGGCGTGAGAAAACC AGAGATTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGT GGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCTCGTCT CTACTAAAAATATTTAAAAAAGAAAAATTAGCTGGGCGTGGCGGCGGGAGGCTACTCGGG AGGCTGAAGCAGGAGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCAAGATTG CACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTGAAAAAAAGAAAAAAAA AGAGAAAACCAGAGATTGATGGATTTTAACAAGCTGTCAGTTATAGCAGCAATACAGTCT GTATACAATAATGAAATTCTACTCTTTTGACAATACTTATTTTTTGCTTTTAGCAGATTT TGGAACAGCTTTGTATACTCATAATTTTACATAATAAAGGCTGAAATGCACAAGTTATAT TTTCATGTTTAGGGTTTTTTTTCTGTTTTTTGTTTTGTTTTGTTTTGTTTTGTTTTGTTT TGTTTTGTTTTTGAGATGGAGTCTTGCTGTGTTGCCCAGGCTGGAGTACAGTGGTGCAAC CTCAGTTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCA AGTAGCCAGGACTACAGGCGCGTACCACCACACCCAGCTAATTTTTGTATTGTTACACGC CTGGCTAATTTTTATATTTTTAGTAGAGACAGGGTTTCACCATATTGGTCAGGCTGGTCT TGAACTCCTGACCTCATGATCTGCCTGCCTTGGCCTCCCTGAATGCTGGGATTACAGGCT TGAGCCACTGCGCCCAGCCTTTCTGGGTTTTTGGGGGTGTTTTGTTTTGTTTTGGGTTTT TTTTGAGATGAAGTCTCCCTCTGTCGCCCAGGTTGGAGTGCAGTGGCACAATCTCAGCTC ACTGCAGCCTCCGCCTCCCACATTCAGGTCATTCTTGTGCCTTAGCCTCCTAAGTAGCTG GGACTTGCATGCATGCGCCACCATGCCCAGCTAATATTTGTACTTTTAGTAGAGACGGGG TTTCGCCATGTTGGCCAGGTTGGTCTTGAACTGCTGACCTCAAGTGATCCGCCTGCTTCA GCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACCACACCCAGCCTCATGTTTAGGTT TTGGATGGATTAAATGTCACAGAATTTAAGGAATACTATAAATTGATGTGATAAAACCAT CGTACTTTGAACTCACTTTCTATAATTTCTATGGAAATGCGTCCACGTTAAATCTCGACC ATATTTTTTTAAAGTCCATGCATATTCTCTGCCTTAAGTGACCTTTAACCTCCCTACTTT ACTCATCTAACCACAATAGGTCTTGAGGTCATCAGGTATTCTCTTACTTTTATTTAGGTA ATGTAAAAATCCACATCTTATATCTCTTGCTCATGGGATGATTAACTGTAATTGGACCAA ATGACATGCGTGGCTCTGCTTTTCCATCAGTAAAGTAGGAGTGGTCATAATTCATTTTTT CTCAGCAGTGACGTTTTTAGCCCACATGTAAGTGAGTTCTTAAGCAGTCTAGAACCGAAA TAACTTTTTGCCCTTGTCTTACTGTTGGTTGTCATTTCTTATTGCTGTGATTATGTGCCT GCTATTAGAAAACCATTTCCTCTTATAATTTGCTCTTCCTGACCTATTATAGTTAGGAAA CCAAACATTAATTATTCAGCTTATTAGAATTATGTTTATAACCAGGATCAAACATTAAAA TTAAATTTGAAGACCCAAGAGATACTCTTGGATGTAAAAATGCATGAGTTTTAGTGTATA TAATGTGAAAAGCTCAGAGGCATCTTGTGTCATTTCTTAGTTCTTAACTGTACATTCTGA GTAATTAATATCAGATAAATGACTTCCAGATAAGTGAAGTTAGTACATACTTATCAGAAA ATCTTTGCATAATTTTTTCCTCTAATAAGACACTGCAATAGAGAAGGAAACATAATTATA TTGAACATCTAATAGAAATGCAGAAATAGATCTTTTTAGTTGCTAAATTGATAGCTAATT TTTAGTATTTTATCTGTTTGCATTTCTACTTTGTCTTAAGTTACTATGTTTATTATGGCT TACAGAATTATACATTGGTTGCTAACCACCTACCATATATAGATAACCACATTGAGCTTT CAGAGTTATGTAACAGTAACACACCAGAAGTGTGCATGTAATAGGATCTTTTAGACTTTC AACCACATGAGGACTTTAAGATAGAACGATGAGCAAGAAGAAAATATTTTCAATGGAAGT GGAAGACTACAGTGATTTTTCAAACACTGTTATATAATAGATTCCTCTTCAAGAATATTA AAAAAATGTTTTCCTAGCATTCCACATTTTATCTCTCATTCTTTAACTATATATTTCTGC CCGCTTTGGTGAGGAAAAAAAAGTCATTTTTAGAGCTGAGTGTTCAAGAACCTTAGGCTA TAGATTCTACCCCATGGAACATTGTCACCCGACGTTAGCAACAGTTTCCTGTAGACAGGT CCCAGTTCAGGCTTCTGCCTGCATCCAAACCTTTTAGGAAAGATGGAACCACTGTCTTTA CTTTTTCCTGTTTGCCAGGTGATAAAACAATGATTATAGAGAAGAATATATGTGCATGGA GAGGTCAGAGAACTAATATAAATGTTTTGGAACCTGTCTCAGAAATTTAGATAGAGAAAA GAAGACAATTTGGAGTTAAAGCTCTTGAGCTCCAGTCCTAGCTCTTCCACTTACTAATTG AGTAATCTTGGTAAAATCACTTAACCTTTGTGAACCTCAATTTTCTTGCCTTTAGAGACA GTAGTGCCTATAACTAGATTATTGTAATGAGCTTATATGTGTAAACACAATTTTTTAAAG TCTAAAATCTCATAATTATCAGGGCTTATTTATTGTTAATGTTTTCTGTAGAATCAATAG CAACTATGGAGGATTTGTGCCCTCTACTCTTGATGGTTGTAGAGTGATTGATTATCACCA TACTCTTTAGACTAGAAAAGCTTGAGTTTTTTCTTTTTCTTTTTTTCTTTTTTTTTTTCT TTTTTCTTTTTTTTCTTTTTTTTTTCTTTTTTCTTTTTTCTTTTTTTTGAAACGGTCTTG CTCTGTTGCCTAGGCTGGAGTGCAGTGGCGTGATCTCAGCTCACTGCAACCTCTGCCTCC TGGGTTCAAGCGATTCTCATTCATGCCTCAGCTTCCCAAGTAGCTGGTGGTGCACCAATA CACCCAGCTAATTTTTGTATTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGT CTCAAACTCCTGACCTCAGGTGATCCACCCACCTCGACCTCCCAAAGTGTTGGGATTACA GGCTTGAGCCACTGCGCCCAGCTGAGTTTTTTCTTTTAAAAAGATGTTTTTTAGAATTGT TGTTAGCATCTCTAGTAATGTTGATAAAAAGGATAGCAGTTATACTTTGGACAATGTCCT GCCTTGGCAGTATATACCCTGCTGTGTATGTGTTTGTGTTATATGAATTATATAAATATT ATATATGGTACATAATTATTATTTAGCTGTCCTTCATCATTAACATCATAGAATTGCACT TCACAGCATTTTTGTATATATTATCTCATTTGATCTTTGCAACCATGGAGTGAAGTATTC AAAATAAACATTATCTGATGGATTTGGGTTTCATGTGGTTAGGTATTTTTATTGTTATTT TAGTTGTAACTTCGATAACCTAACTTAGAAGCTTCTAAATAATGAAATATCCTAAGCTAA ACTAGTAATTGAAAAACAGTATTCCTCTTACAGTTGCTGTCATTTTGTCTTACTACATCA TTATGGAGTTTTTTGTCATATGATCAAAAATAAGGCTATTTCTGAATCTTAGCAGGGCTA ATATTATTCCTCCAGTTATTCCAGTGTTTCTCAAATGAAAGTTGTTGATATAACGCTAAG AAGATCCACCAGGAAGTTCATTTATATATACAAAAGTTATAAAACTCCAGGCAAGTGATA GACGGCAATACTGGTAATATAGGTCATACAAATGAGATAACTCAGCCTCTCCACCTTCTG AAGCCTGTCCTTCCATTTCCTCTCTTAGATTTTAAAACCTGCTGGTATGCTAAGAAAGAT GGAAGGGAAAGGGAAGGGTTAGGATCATTTTTAATTTCTTTTCTTGTTTTTAATTTTTTT TTTTTTTTTTAGAGATGGGGTCTCACAATGTTGCCCAGGCTGGCCTTAAACTCCTGTGCT CAAGCTGTCCTGTCACCTCAGCCTCTTGATTTGTCGGAATTACAGGCATGAACCACTGTG CCCGGCTTAATTTATTTTCTAAATAGATTTAGATGAAAGTAGAAATTTGACAGAGTTGAG AGAAAATTATTTTTGAGCTCTATTGTTTAACCACAAGCCTAAAACAGAATTACTTTATTA CTTGTCTATTAACAGAAATGATGAGAAGTTTTTAAATGTGATTTTAAAATACTACTAGTA TTTGAAATGGTCAGAATCCCCAGAGGAAATACTGAATCAGTTTGAGGTAGAAAATAGTGA GGATTAAGATTTTTATATTAAAACACCTTATCCAGACAGCTCAGTAGTCTGTAATCCACA TTTTGTCCTTATTTTCCCCCTCTTTACAGCATCTTCACCAGGCAAGAGTTCAATATATGG CAGTTTTTCAGATGGTATAATATGTTTCATTTTATTATGGTGTGCTTAGTTTCTTTGTCC TTTTTATCCCGGAAGTTTCACCAATCCCATTAGATACTTAATGGGTCAAATACTTCCAAA CTTTCTCTCAAAACTAATTATTGTGTGCTTTGTACTAGACCCCACCATATGCTGTGAAAA GCTATGAAAGAAATAGGTCATGTGTTTCAAGGAGCTCTCAGTCTAATCGGCACTCAGATA TTCTACTTTTTCTTCTGCTTCTGGCTGATCTCTGTCTTCTTTTTTTCCTGGTGGAATTTG TATCTTCTTTGTCTACTAGAAATAAATACTCAAATTATGAAGCATAAGTTGATAGTCTTA TTTTATTACTCTCACCATTAGATGACAGCATTCTGAAATCAGAGCTTGGAAACCAGTCAC CATCAACCTCCAGCCGACGTAAGTTTATGTATTCAGTTTTTATTAAATATTTCTGTAAAA TTGGTATTCCATAATTGTTTAAAAATGTTTTTTGACAGCAGTATGACTCGATGCTATTTG AAGAATCACATTTTAAGCACTTGAGAGGAAAAAGTATATATTCTACTAGCAGTGAAATTC TTTATAGACAAACTTTATGAGACAACATCTGGTATTGCTCTTCACTTAACTGTCTATAAG ACCAAAAATAATAGCTAAAATAAGTAAAGCTACTAATACTGTTAACTGAGAAAACCATGC TGAATTGAAAGAAAGTTAGCCAGAGCATGACTTTATGGGATTACAATGGCTTTCGGAGTC TGCAAACCTGTATTTGAACTAGATTGGACCACTTACCTCCTTTACAGCCTTGTGGCAAGT TTCTTTAGTTCTCCAAGTCTTATTGTCCTGAAAGAGTACTAAGAAAATAACTTAATGGGC TGAGCGTGGTGGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCCAAGGCAGGCGGATCA TGAGATCAAGAGATCGAAACCATCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAA TACAAAAATTAGCTGGGCGTGGTGGCACACGCCTGTTGTCCCACCTACTCAGGAGGCTGA GGCAGGAGAATCACTTGAACCCAGGAAGCGGAGGTTGCAGTGAGCCGAGATTGTGCCACT GCACTCCAGCCTGGCAACAGAGCGAGACTCTGTCTCAAAAAAAAAAAAAAAAGAAAATAG ATTAATGATGATTCTGAAATTTTTTGTTCTTGGTACCGCTTTACACTAGTAAAGTTATTA AGAACCTCAAAGAGCTTTTTGTTGAAAATATGGGTTATGTCTATCCATATGTACCAGGAA ATTAAAGTTGAAACATTTTTTAAAATATGTATTAATTTATTTTAAAATAATTTAGCAAGA AGAGTAACAGATCAGATTGCTTTGCATTTTTTCTAATCTCTTTAATGCCTAGCTTTAAAA AATGGATTTGGATTATCATATATGCTTCTGTATGCAGTCTGTTACAATATATTATTTTTG TTGAAGTATCTACAAAAAATCCAGCTTTTATACAGATATGAAAAATTTTAATAGCCTCTT CAGATAATTGTGGCTATTCTTTTTTGAACTCTCCAAAACTCAACAAGTGGTAGTTTCTTA AATGTTACTTGAAATAGGATATCTAAAACCATCTTACTGAGCTTTTAGTACTCTATTACA TTAAAAGTCATTGGTCTTTCTTATACTTTGAATGGAGTATCATGCACTGGTCATTTGGAA AACATTGGTTCACTGAGGAATGCAGATTTTCCAAACATTGACACATTAGGAATGTAATAA AAAATATCACATTTGTTAACATCACTGCCAATCTCAAGACTTTAAAAAAGTGTTAAAGGG TGGGGTTCGTGGCCCATGCCTGTAATCCCAACATTTTGGGAGGCCCAGGCGGATGGATCA CCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTACTAGA AATACAAAAACATTAGCTGGGAATGGTGGCACGCACCTGTAATCCCAGCTACTTAGGAGG CTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGCAC CACTTCATGTCATCCTGGGCCACAGAGCGAGACTCCATCTCAGAAAAAAAAAAGAAAGTG TTAAAGTACAATATTGGGAGTTGTCAAGCTCATGGTGGCAGATTTAGGATTCTAAAATCC TAATTTTCACTTGAAAGCAAATATCTGCCAAATACACAAGTCTGACTGTAGTTTGTTACT TGTTCTTTCAAGTAAAAAATAGTATTCCATGAAAAATGTGCTAATTCGCCTTGTAATTCA TTTGCACAAAATTCTTTTCCTTGAGACAACCATGGTACTGTATGATGCAGCAGAAGTGCT TTGTGCATACCTTCCATTTGTTCAGAAAGAATATTGACATATGTACTCAAGGATTCAGAT TTAATAAGATAAATAATTAACTGCTTCATAAAGGACATTCTTAAGTAAAAGAATGTCCCT TTGTTAAATCTTGAATGCATGGCAGTGAAAAATAACAATGACTACACTCGTACAGTTTGG TGCCACTGCCCTGTAACTCATGCTAAGGCATCAGAAGTTTTTCTCACCATAGCTTTTGCG TCATCAGTGCAAATGTCAACACAAGGTGAAAGTCAAATAACATCTTAGTGTTAGAAGAAT AGCTTTAACTTCATGGACCCCCCTCCCCACAAAATAGGGTCTTGAGGTACCCCACAGACC ACGCCTTGAGAATTGCTGCTCTAAAAGGTCCCTACTAAAATTAATAGCCTGAAACAGTCA ATAAGTAAAAGATGTAAAAGTATTATTGTTACTATCAACTGAATAAATGAAGTAGAATAT GAGAAAGTACTTTATAAACCGAAAAGCACTAGATAAATATAAATTAATCCTATTATTATT GCCAATAGTAACTAGGGATGAGTCACAAACTAAATTTTACCAGTGTTAACTTGCATACCA CAAAAGGCATCAGTGAAATTAATCTAAAGGGACAGCTAGCTATTATAACACGTAGAAGAT GTTCATTTATATTGCATCCTTTTCTTTTTTTTTTTTTTTTTTTTTGAGATGGAATCTCTC TCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCGCCTCCC GTGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGACTACAGGTGTGTGCCAC CACACCCAGCTAGTTTTTTGTATTTTCAGTAGAGACGGGGTTTCACAGTCTCGATCTCCT GACCTCGTGATCCTCCCTCCTCGGCCTCCCAAAGTGCTGGGACTACAGGCATGAGCCACC ACTTCCAGCCTGCATCCTTTTCTTTATCCCTTTATGTACTTCAGAAATATTTCACCTTGA ATAATTAGCCATGTGAATGCTGAGTTACTAAATTAAAAAAATATTTTATAAATTGTATTT TAATAGTCTATTCTCCCAACTATTAGCAGTGAAAATAATAACTTCGCTTTATAAACTATT ATTTTTCTGACTTGTTTATGCCATTTCATATGTTTAAAAACTTTTTTCCTCAAAGACTTA TTTTTATATTGAAGAGACATATGCATATTTGTACACATAATTCAAAGCCTATGCATGTAA GATTTTCTTGAGAATGTGATAAATTATTTTATTAAGAAAATTATCAGCTTTCTTCTTTAA AGTCCTTCCTCTTTTACCTAATGTTTATAAAGACTGATATTGATTTTAAAAGTCACTTGC CCCTGAATCTAAGAAAGTGGTATTTATATCTGTCATTTCTTTTTTGTCTGAGTAGAAGTG ACTGGACAACCCCAAAATGCATCTTTTGTCAAGAGGAACCGGTGGTGGCTACTTCCTCTG ATAGCTGCTCTTGCCTCTGGGAGTTTTTGGTTCTTTAGTACTCCTGAGGTAGAAACCACT GCTGTTCAAGAGTTCCAGAACCAGATGAATCAACTTAAGAATAAGTACCAAGGTCAAGAT GAGAAGCTGTGGAAAAGGAGCCAAACATTCCTGGAAAAACATCTTAATAGCTCCCATCCT CGGTCTCAGCCTGCTATCTTACTGCTCACTGCTGCCCGAGATGCTGAAGAAGCACTTAGG TGTCTGAGTGAACAAATTGCTGATGCCTATTCTTCTTTTCGTAGTGTCCGTGCCATCCGG ATTGATGGGACAGATAAAGCTACTCAAGACAGTGATACTGTCAAACTAGAGGTAGACCAA GAACTGAGCAATGGATTTAAGAATGGCCAGAATGCAGCTGTGGTACACCGCTTTGAGTCA TTTCCCGCAGGCTCTACTTTGATCTTCTACAAATATTGTGACCATGAAAACGCGGCCTTC AAAGATGTAGCCTTAGTCCTGACTGTCTTATTGGAGGAAGAGACACTTGGAACAAGTCTA GGCCTAAAGGAAGTTGAAGAAAAAGTAAGAGATTTTCTTAAAGTCAAGTTCACCAATTCT AACACACCCAACTCCTACAATCATATGGACCCAGACAAACTGAATGGCCTCTGGAGCCGT ATTTCTCACTTAGTTCTGCCTGTGCAACCTGAAAATGCCCTGAAAAGGGGCATCTGCTTA TAAGAAGTGAGAGAGAAGAAAAATCATGTCCCAAGTTCTGAGAATTGTTCACACTTTCTA ACCAGAGACAGAATTCAGAGCTCTTTTTGAAAGAACTAGTTTCTTTTTAAAGAAGTTAAG TGCTTACATAAACATGGAACATATAAATCATTCATTCAACCTAATTATCTGTGATATGAG AGAATCATTTCAGTTTCCATTGAGAGCTCTGTTAAAGGTATCTTAGGAGTGCAGATTATA TGCAGTTCCTTAGAGAATCTGTTTTGATTCTGGGCTGAGTTATTACAGTTATGGTATGAC CAGTGAGAGGGATTTGTGTCCTTTCTTATGAACCTTCCTGATTTTTTAACTTAGATTTCT CACTAAGTTTCCTGAGTTATTAGTAAGATTGCTCCCTAAATGTAACCAGGGATTTTCCCA TTATGTTCCCTTTTATACCATTTAGGTGTGAGTTCCTTAGCTTCTGCCTATAGGAACATA AGTAATGAAAGGTCATCTAGGTGTGTGTTTGGAATTTTTTTCTTTTGTTTTTTGGAAAAT GGAAAGAACAAGGCAAGGAAGGAAAATTAATGGGGAAGCTGAAGGGAGGAAATGTTACAG TAATCCACTGAGATGTAGTTTAGTCAAACATAGGTATATGAACTGTTAATCTTGGTGGAT TCCGTTGGGATTTGTTTTTTACATCTCCTTTTTCCTTCCTTGAAGAAAAATTCTTGGCTG TCCCAAGGATTCTTCATGTATATTGCAAAATTTAATATATTTGTTCACTTGAGTCTTAAG AGTAGGTCAGGCCAAGGCAGGTGGATCACCTGAGGTCAGAAGTTCAAGACCAGCCTGGCC AACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGCAT GCCTGAAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCG GAGGTTGCAGTAAGCCGAGACCATGCTTATTGCCCTCCAGTCTGGGCAACAAAAATGAAA CTCCGTCTCAAAAAAAAAAAA bcftools-1.21/test/csq/ENST00000271583/ENST00000271583.fa.fai000066400000000000000000000000211467060157400215340ustar00rootroot000000000000001 36981 25 60 61 bcftools-1.21/test/csq/ENST00000271583/ENST00000271583.gff000066400000000000000000000074161467060157400211710ustar00rootroot000000000000001 ensembl_havana gene -254 42704 . + . ID=gene:ENSG00000143337;Name=TOR1AIP1;biotype=protein_coding;description=torsin A interacting protein 1 [Source:HGNC Symbol%3BAcc:29456];gene_id=ENSG00000143337;logic_name=ensembl_havana_gene;version=14 1 ensembl_havana transcript 1 36981 . + . ID=transcript:ENST00000271583;Parent=gene:ENSG00000143337;Name=TOR1AIP1-011;biotype=protein_coding;havana_transcript=OTTHUMT00000393092;havana_version=1;tag=basic;transcript_id=ENST00000271583;version=3 1 havana five_prime_UTR 1 206 . + . Parent=transcript:ENST00000271583 1 havana exon 1 681 . + . Parent=transcript:ENST00000271583;Name=ENSE00002179326;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002179326;rank=1;version=1 1 havana CDS 207 681 . + 0 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 2396 2473 . + . Parent=transcript:ENST00000271583;Name=ENSE00003536688;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003536688;rank=2;version=1 1 havana CDS 2396 2473 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 7014 7073 . + . Parent=transcript:ENST00000271583;Name=ENSE00003591554;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003591554;rank=3;version=1 1 havana CDS 7014 7073 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 17830 17871 . + . Parent=transcript:ENST00000271583;Name=ENSE00003633018;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003633018;rank=4;version=1 1 havana CDS 17830 17871 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 19006 19092 . + . Parent=transcript:ENST00000271583;Name=ENSE00003483184;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003483184;rank=5;version=1 1 havana CDS 19006 19092 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 21670 21726 . + . Parent=transcript:ENST00000271583;Name=ENSE00003703708;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003703708;rank=6;version=1 1 havana CDS 21670 21726 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 25527 25568 . + . Parent=transcript:ENST00000271583;Name=ENSE00003707546;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003707546;rank=7;version=1 1 havana CDS 25527 25568 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 26309 26377 . + . Parent=transcript:ENST00000271583;Name=ENSE00003711472;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003711472;rank=8;version=1 1 havana CDS 26309 26377 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 31290 31334 . + . Parent=transcript:ENST00000271583;Name=ENSE00002193587;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002193587;rank=9;version=1 1 havana CDS 31290 31334 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 31702 31758 . + . Parent=transcript:ENST00000271583;Name=ENSE00003633147;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003633147;rank=10;version=1 1 havana CDS 31702 31758 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana CDS 35156 35943 . + 2 ID=CDS:ENSP00000271583;Parent=transcript:ENST00000271583;protein_id=ENSP00000271583 1 havana exon 35156 36981 . + . Parent=transcript:ENST00000271583;Name=ENSE00002189988;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002189988;rank=11;version=1 1 havana three_prime_UTR 35944 36981 . + . Parent=transcript:ENST00000271583 bcftools-1.21/test/csq/ENST00000271583/splice-acceptor.txt000066400000000000000000000013611467060157400224710ustar00rootroot00000000000000643 T C missense|TOR1AIP1|ENST00000271583|protein_coding|+|146M>146T|643T>C 643 T C missense|TOR1AIP1|ENST00000271583|protein_coding|+|146M>146T|643T>C 646 C A missense|TOR1AIP1|ENST00000271583|protein_coding|+|147T>147N|646C>A 646 C A missense|TOR1AIP1|ENST00000271583|protein_coding|+|147T>147N|646C>A 7013 G A splice_acceptor|TOR1AIP1|ENST00000271583|protein_coding 7013 G A splice_acceptor|TOR1AIP1|ENST00000271583|protein_coding 25557 C G missense|TOR1AIP1|ENST00000271583|protein_coding|+|277P>277R|25557C>G 25557 C G missense|TOR1AIP1|ENST00000271583|protein_coding|+|277P>277R|25557C>G 25561 A G synonymous|TOR1AIP1|ENST00000271583|protein_coding|+|278S|25561A>G 25561 A G synonymous|TOR1AIP1|ENST00000271583|protein_coding|+|278S|25561A>G bcftools-1.21/test/csq/ENST00000271583/splice-acceptor.vcf000066400000000000000000000016231467060157400224310ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 643 . T C . . type=ENST00000271583:179852074-T-C;EXP=missense|TOR1AIP1|ENST00000271583|protein_coding|+|146M>146T|643T>C 1 646 . C A . . type=ENST00000271583:179852074-T-C;EXP=missense|TOR1AIP1|ENST00000271583|protein_coding|+|147T>147N|646C>A 1 7013 . G A . . type=ENST00000271583:179858444-G-A;EXP=splice_acceptor|TOR1AIP1|ENST00000271583|protein_coding 1 25557 . C G . . type=ENST00000271583:179876988-C-G;EXP=missense|TOR1AIP1|ENST00000271583|protein_coding|+|277P>277R|25557C>G 1 25561 . A G . . type=ENST00000271583:179876988-C-G;EXP=synonymous|TOR1AIP1|ENST00000271583|protein_coding|+|278S|25561A>G bcftools-1.21/test/csq/ENST00000285021/000077500000000000000000000000001467060157400166425ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000285021/ENST00000285021.fa000066400000000000000000001024351467060157400207720ustar00rootroot00000000000000>3 3:14145127-14178621 AGAAAATATAGAGCCAAATCTTTAGATAAATGCTTTATTATTTTCTCAAAATGTTATAAA AGTCATTTCTCCTTAGTACAGAGAGCTTTATACATTTTATCTAGTAATGAATACAATCTA GTTTAACACTCATCTATTTTACTAACATTTCCTTAATTTTCAATTCGTATTTTTCCTTTT CTTTCCTGATTTTAGCTTTTTTTAGGCTTCTGTCACCACAAAATGTTACTTGGAAAACTA GATCCCAGCAGATGACCTGTACTTCTCTGCTCTCTCCCCTACTGCAAAGAGGCAGTGAGG GCAGCATTAGTAAGCCTGACTCAGGGGAAGGTAAGTGGCCTGCAGAGAAATGGTCCTAGG TCCGCAACCGAGGCGAGTGAACTTGTCGGACAGATGAAGACTCTAACTGGAAGAAACGAT CAGCGCATTCACGGATGCACCACCATCCAGAAATCTCCCGGTGGCTTCCATACAAAAACT GATGTTTCTAAAGATGGAAAGAACAGGTCTAGGAGGCAGAAGAGTATCTCCTAGCAAAGT GTTCTGTAGCTCAAAGGGTGAGTGGGCTTTGGTAGCAAAAAGCTTTGAAGGCTTCACCCT GGGTGAATCTGACAAGGGCTGGAGCCAGACGGGACCTGCAGCACCTCCTCAGCTTGGCCT CGTCTCCCCTGACCCCGCCTCCGTGCATGCTGCCTCAGTTTGCCTTCTCAGCAGAGAAGC CCCCACCACCAGGGGCTGGGCATGCCCAGGGCAGGTGTGGGGCCTGTAGTGGGGCAGCAG CAACTGGTGGGTGCCCCTCTAGTGGGCGCTCAGCTCACAGCTGCTCAAATGGGAACAGGT GGGAAGCTGCTGCTTTCTTTTCCCTTTTGGTCTTCTTGGGCCCACCCTTCAGCTTCTGCT TTTCTTCATCTTCTCGGTTTTGAGGCCAGGAGGCAGCCAGTATCCTGGCCGCTTCTGCTT GAGAGCTGGTCCCCTCCTCTTCATCAGAAGAGAGTCCACCTCCTGCATCTGTGTGGGGAG CTGCTGCCTCACTCTGGACAGGTGGCAGTGGTGGGAGGACACAGGCGAGGGTTAGTAATC AGATACCAGGAAGCCCCATGAAGAGGCAGCAAGTTCCCAGCCTGCCCTAAGCTGTGTAAC TCTGGGAGGACAAGGGCATGGGACAGGGCAGGGAGAGAGCCCAGACCCTTCTTACTGAGC CGTCCCAGCCTGGGGTGCATCCAAGCAGACACTGGAGCACCTGCTACGAGCTGAGTGCAG GGGAACACAAGGATGATGGCTGGGCAGGAAGCTGCCCTCTAGGAGCACACTGCCTCATCT GGGGATGCCTGTGATTCGTGCCTTGCATTTGCTACCTCATTTCTGGACCAAAGCACATGA TGTCTTGAACGGGCAAGATGCACAGTTCAGCCCTCGGAGCCCTAAGATCTGAGGCGGCAC TCCCTGCCAGCTGGGATGGCTAGGGAGGGTTTGGATGGAGAAGGCGGCAAGGAGCTGGTC AGAACATAAAGTCAGATGAAGGGCTTTTCTCCACCAGAGGGACTGGAATGAGGAGCGTGA CAAAAAAATGTTGAAAGGCAAACAGGCAGCACAGAGGGTTGGAGAGAGGGAACAAAACAT GCCAGAGCAGTTTCTGCTGTGTCTGACACAGCACTGACTATACCATGTAACTGGGCCTAG GGTCCATCTGCCCCAGGGAGGGGCCCCCTTGAGGGCTGCATGTCAAATTCACACCTGTGT CCAAGCCTGGCCTGGCACATGGCAGGTGCTGTGAGAGAGGTACTGAGCGGGCCACTGCAG GCCTGCAGCATGGTCACAGGCACTGGGAACACTGGAAGGCGGAAGGGTGCACCAAATGCA GGACACTTGGCCCTCCCTATGTGTTCAGCGCCAAATCAGACCCATGGCATTGCTCATGTG GACAGTAGAAACGGGGACACTGGGACAGGGCTTGGGGCAGAAGAGCCAGCTGAGGCCTCA CTCCAGGGACACCTTTCCCAACAAGGTAAAAACAAGCGGCCTTAGAGACAGAAGACTGAG GTGTCCTAACACAAAGCTATCCCTGACTTGAGGCTGGGGCAGAATCTGGGCCAGGCCTTT CTGAGCTGCATCTCCAAGAAACTGACCCTGAGCTTGTCTTCTCTGCAAAGAACCTGCACT GACCTTGGGCCCGTAGCGACGCTTCAGCCTCTCCCTGATGAGCAGACCTTTGGCCAGCAA CTTCCAGTTCCCTAGAGCCCGCTTCTCCTTTTTCTGCAGGCAAAAATGAAGTGGGAGAAA AGTGTTAAGCACTGACATTTTCAGGAAAAATATTAAGATGGAAACTGTGAATGTAAAGAC AGATATATACACCACTTTAGAATATAGCCTCTCCTTCACACCAAGTCTCACTTCCAAAAA ATTGATCTGATTTACAAAGTGATATACTATACCTGAAAGCCACAAAAACAGATAACTTTT TAATCGTTACTGACTCCAAAATCTTTAGTGGGTGAGGTCTTCCAGAACCTGGACACAGGC AATTCAAGACAGAGGCAGGTGTGGGCAGCAGGGGCAGTAGACCCCAGAGCCCGGACCCAG GCTCCTCAGGGACAGTGATAGTCTGCGGGGTGGGCAGGAGCCTGCTGTATTCAGTGCTCG CTCCCTCGGGTGCCTGCCATGATGTCAGAGAGGGCTGGGAAGAGCCTGGGAGCACACGGA GGCGGCCTGGGGAAGGAAGAGGCCACCCGCTGAGTGTTGCTTCCCGCTTCTGCTGTCCCT CAGTCCTGCATATGCGCTTACCTCCTTCTCCTTCCTTTCAATGACTGCCTGCTCATTTTC CCAGGCAGTCAGGAGCACGTCTTTGAATTCCTCGCAGACGATGTATCCATCAGTCCTGTG GGGACACAACGCGATGTCAACCCTCGAACCTGCTGCCTGCTCTGCCTCTCCTCCCTCCCC AGTTTGTGGAAGACAGTGGGCCACATCTGAGCACTAGGGGTCCTGAAGGATGTCGCGGGT CAGCCAGTGTCCCACATCCTCCGTGCAGAAGGCAGGCCTGTGGAAGCTGGCACTGCCTCT TCCTCCCCAGATTCTGCCGAAGAAAGCTGGGGTGAAAGCCCCTATCCAGCCTCACCCATC ATGGAACAGAGCTCACTAACCAGGCAGCTGCCGGGGAAAGATGCTGACTGTTTTTTGCTC ACTAGCCTGTGAGTCCCTAAACCTGGGAAGAACGTTTTAATCCAGCATTACGATGCCAGT TTCATTGGCTCCGTTCCCTCTGGAGGGAAGCCAGAATTGGTAAAGCACTGACTTTGCAAA TCCAGTGTAACATCCTGAAAATTGGAGCCACCAGGCCTCAACTCCCAGCAGCCCCATGCC AGCTTTCCATCCCCATCTCTGGAGCCACCCCTCCCCATCCCTGTGTTTAGCCTCCATCGA AGGCCCCTCACGCACACGGGATGGGAGTAGCCGCCATGGAAATCAAAGCCAGTGATGGCC TGGACACAGTCGATGTCCAGCTTGCGGGCCACGCGGTGTAGATTGGGCAGGTTCAGCTGG ACACAGCCAATAGGCATCATGCTGGGCAGGAAGAGGTACACATTCCCAAACTCGTTCCGG GGCACCTGTGTCGGGTGAGCAAGTCAGCATTTGGCCAGCAGGGGAACAAGGCGGCCTGGT CCTGAGCCCTTCTGATGCTGCCCTTACCTTCCCGTCCACGGCCACTGGGGGCTGATACTC CTCTGTCTGCCAGTAGCCAAACAGGCCCAGGTCATTTTCTTCCCGCAGCTGGGGCTCAGC AAGTCGGGCTTTCCGAGCACGGTTAGAAAAGCCTTTCACCATCTGCACCAGAGGACACGG CCACCGTTTACAACAAAGGCATCCAGTTCCTCAGCACCGGGCCAGGCACCATGCTCAGTG CCGCATGCCTGGTACCTGGTGAACCCTCAGAACACACCTACCAGCTGGGGTGCTTTTTCT CCCTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTACAGTGGTGC AATCTTGGCTCGCTGCAACCTCTGCCTCCTGGGTTTAAGCAATTCTCCTGCCTCAGCCTC CTGAGTAGCTGGGATTACAGGTGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAGT AGAGACGGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATG CACTCGCCTCAACCTCCCAAAGGGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCTGC TCCCCTTTTCTTACTACAAGCACTAGCTAACATTTATGGAACATTCTCTGTCCCAGACAC TATTCTCGGTGTTTTTTGTTTTTTTATCCCCCTGAGACGGAGTCTCACTCTGTTGCCCAG GCTGGAGTGCCCTGGTGTGATCTCAGCTCACTACAACCTCCACCTCCCGGATTCAAGTGA TTCTCGTGCCTGTCTCCTGAGTAGCTGGGACTACAGGTACCCGCCACCATGCCCAGCTAA TTTTTATATTTTTGGTAGAGATGGGGTGTCACCATATTGGCCTGGCTGGTCTCAAACTTC TGACCTCAAATGATCCACCTGCCTTGGCCTCCGAAAGTGCTGGAATTACAGGCATGAGCC ACTGCGCCCAGCCTATCTTCAGTGCTTTATATGTTATTATTTAATTTTTTCAACAAACCC ACAAGGTAGGTCTTATTATTGTTTCCATTTTACAGATGAACACCACAGACGGGGTAAATG ATTTGCCTAAAGTCACACAGCTCGTAAGGGCCAGAGCCCACACTTTCATCCACTAGCCTA TATTCTGTGCTGTCATCACTGATAGCAGTGACTGAGACTGAGAGACAAAGTCACTTAAGA GCTGATGGCTGGTAAGTGACAAGAACCAGGATTTACAATTCAGGTAACTGTCCATCAGTA GAGCCTGTGTCTCAACATATAACCTATGTCTGCTCACACGCCCTAGAAAGCACTGACAGT TCAGGACTCCCAGTGTGCTCCCCAACAGCGTGCAGTGGCCAAGGCCAAGATCTTCCCTGG GGAGTGAAGTGGTGAGAGGGGCGCAGGACAGGCAAGGACAGAGTCACGTAACTCTTAGAG GAGTCAGGCATGGGCGTGCGGCTGAGGGCTGGCCCCTGGGCCTCAGCATACAGACTTCCT CTAGTGCAGGGGCCCACAAGCTTGTTCTGTAAAGGGTCATGCGTGGCCTCCATCACATAT TCTTTATTCTTCTCATTCTTATAACCCTTTAAAAATGTGAAAAGCCATTCCCCAGGTTGG GGGTGGCCTGCGAGCTCTCATGTCCATTCCTGCCATGATCTCTGGGCGCACCCTCTCTGT CACCACTTCAGGGACAGAGGGACTCTGAGTTCTGACAACCGTCCCTTTCTGAGAAGCCAT TCACCCAGCACACTGTTCAGTAAACTTCCACTGGGATCTCCTGGAGACCAGGCCATGACC CAGTCATGAAGGAGGGATGGAGCGAGGACAGTCTTTGCTCTTAGGAGCTCAGGCTCCTGC AGGGGAAGAGACAGAGCTACGACTCAGCGTGATGAGTACAGGGTGGAACAGGAGCTCAGA GGCAAGCCATTGCCCAGCCCTGAGGACAGTGGAGGCAAGAAAGGCTGCTCAAAACAGGTC CCGCCTGAGCAGAGGCTTAAAGGGGCAAGGGGTTGCCCAAGAGAACAGGGCTGGACCCCA CAGGGCACAGAGGTGGGAGAACACTGGGACCTGGGGCCTAAGTCCTCTGGAATGCAGAGG CAGTGAGCACCAGAACATCACTGTGCACCATGGGGAGGGTGCGGGACTCAGACTAAAGGC GCTGGCCAAGGTGGGACAAGGATGGCCAAGATGCACAGAAAGAGCCTAGTGACTGACAGG GGAATGGATTCAGGCTGGGAAGGAGGCTGTGGCTGTTGCCCAAGCAAAAGATACTGAGGC AGGAGCTGGGGTGGTGGGGATCAGAACAAGGGGTGAATTTGAGAGATTTGGGATTCCAGA ACTGTGCTACCATGACAGCCACCAGTCACGTGTGGCCACTGCACACCTGAAACGTGGCTG GTCTGAACTAAGGTACAGAAAGTCAAATACACAGAAGATTAGAGAGACTTAGGAACAAAA TGGATTTAAATATCTCATCAACACTTTAAAATATTTCTTACTGCTGAAATAGTATTTTAG ATATATCTGGATATATTTTAATGTTAAAATTCCACCTGTTTTTGGTTTTTAATGTAGCTA CTAAAAAATTTAAATGTGTGGCTCACGTTACATTTCAACTGAACACTGCTATGCTGGTTC CAGCACAAAAGACAGGTGAGATGGTGCAGAGAAAATCCTCAGCAACCCTGCAGGCCCAGG CAGGGGGCATCGCCCACTCCAGCCTGCTGCTGGCAGTGACTGTGACCAGCGCCTGCAGCC TTTCCCACTAAGCGGAGGCCCCTCCACTCCCCACTCAGCTTCCCGGAGTCTTGCAACCCC CAAGGACTCCTGGGGTCTGATGAGAAGTAAATGGTCTCTGTGATCAGCCACTGTACACTT CCGGTCGTACGGAGCTGTGTGTCCTGTGAATAGTCTCTGTGGGACCTCGCTCGGTTCGTG TTCCTCAAGAGCAACCAGCCTAACAGTGCCGCAGCACAGTGTGAAAGGAGCACTGGCTTT AAGGCAGAGCCTGGGATTCTCACCTGGGCTCTGCTCTGCCATTTTACTAACTGTGGGGAC TTGGACAAGTCACTTGCCCTGAGCTTCAGTTTTCTCATCTGTAAAATGGGCATCATAATG CCAATTCCTATGGCTTTTGAGGCAACAGAGATCACATACATGCAAAATGCTCAGTGAACT GCCAAACAGAAGGGCAATCTGACTGGAGAACGTGCTGCTATAAAGCAGGGCTCTGACCTC CCAGGACCCAGTAACTCAATTCCAACCTGTAGAACCTTTGAATTCACAACAGGAGTCTGA GGCCTACTTTTTGGCCTAGATTTCTTTTGTGTTTTGGAAGATCCATTTCTTACAAATGTC TTATTAATAAGACAATTTAAATGTTTCTCTCCTCCTTGAATCCTGCTCAAGCCGGGAAAG TGAGACATTTCTGATCAGGATCCTGGGCAGGACTGGGAGGCTCATCATCACTTCTCTGCC CCCAGCTCTCCCGCTCAGCTACAGGCCTGTGTCACCACTCCCCACAGGGACCCCCCAGCT CCAGTTACCTTGTAGGGTACTTCTCCAAGCCTCACCACTCTTGCTTTCTTCAGCCACGTG TCCCTGGAATGCAGAGTGTGCACACAATCCCTGTGGAACCAACACAGGACACAAAGGTAA CTCAGTCCACAGCCCCACTGCGGGAATGCGGGACAGTGGAGAGCGCAGCCCTGCAGGCTC CCTCCTCAGGTTCAGCCACCCTGGAGCAGGCCGAGCTCCTAGGGGGCCCAGAGAAGCTGT GCTAGGCAAACAGCCTTGAACGTGGACTGCCTGTCTTTTGGGGGATGTGTCCACTTACAA ACCCTAATCTGCAGCCTTTGTGCCTTGCCTCCACCACTCCTCCCCTTCATAGGTTTTCTT CTCCTCTGCTGTCCAGAGCCTGTGAGAGCTCCAGCTGCAGACTATCAGGATGGGGTAAAG GCCGCTGTGCGCAGGCACACTCACGTTTACTACCACCACCAAGCGAACACCTGCTGAGGC TCTGATCTGCTGTTAACACCATGTGGGGGAGGGAAGTGTCCAGGAGGGGGCAGTGAACCC AAAGGAAGGCTGCAGAGAAGCCAACTATAATAAGCTAATAAGCTATCACAGAATCAAGAC ACCTGCACATGGAACAGTCAAATGATTCCTGCAGGCAAAGTTCCTCTGGCTTCACTCTTC CTCCCGAGCTAAGAGCTCACCAAAGCCGTGCAAATCTACTTTCCAATGAGGCTCAACCCC TCCCTTGCCAAGCCATTTTTAATAAGGCACGCCCATCTCATTAGTTTGCACCCCCTTCAC TCTGTCCAGGGAGCGGCTCCAATGAGCAAGGGCACCCCATTTCCTCCTAGTGCAGGTTCA GACCCTTACCCACAGAGGAATCTGAGGCTGAATTTCAGCACAGCACAATGGATGGAGGTT GAACCTTGCCTGTGCCACTTCCTGGCTGGGCCACCTGGACAAGTCACTTTACCTTCCTGA GCCTCAGTACAGACAGTCCCCAAAGTCCAGTGGTTTGATTCAAGATTTTTCAACTTTATG ATGATGCAAAAGCAATATGCACTTGGGAGAAACTGTGCCTCAAGTACCCATACAACCATT CTCTTTTTCATTTTCGGTATTCAATAAACTACATGAGATATTCAATACTTCATTATAGGC TTTGTGTTAGACAGCTTTACCCAACTGTAGGCTAATGTGTTCTCAGCACGTTTAAGGGAG GCTCAGCTAAGCTATGACCCATGCTACATACAACAGGAGTGAACCTTGAGGACTTTATGC TAAGTGAAATAAGCCAGTCACAAAATGACCATAAATACCGTATGATTCCACCTACATGAG GTCCGGTTAGGTTCGGCAGGTTAGGTATATTAAATGCATTCTCAACTTAGGATATCCTAT TTTCAGCTTCCAATGGGTTTATGGGGATCCAACCTCATCCTAAGTCAAGGAGCATCTGTG TCCTCACCTACCAACTAGGGACAGTGAGCTTGCCCTTTCTACCGCACATGGTTGCTGGGA GGACCAGACGTTTCCTGTGTGCCAGAGCAGCGCTTCTGCCAGTAGCACCAACCTGCCAGA GCTCAAAGCTCCACTCATGCTCCCACTGGGGGCGGAACATCTTTGACTGCCCAGAGGAGT GATTATGTCATGGTCGTGGTCTTCAGACAGGAGCGGGTAAAAAAGGGGTCTTAGGGGTTG ACAGGTAGGCAGCATCTGGACATCTTCCTAAGGAAAACAGCAGGGAAATGGACACAGTCC TCTCAGAATAAATGTGAACTTCTAACCATTTCACACCCGTTAAAATGGCTATTAACAAAA CACAGAAAGTAACAAGTGTCAGTGAGGATGTGGAGAAAGTGGAGACCTTGTGGACTGTCG GTGAAAATGTAAAATGGGTGCAGCTGCGGTGGAAATGGTAAGGTGGTTCCTAAAAAAATG ATGGGAATTACCATCTGGCCTAGTAATTGTACTGGGTATATGCAAACAAACAAACAAACA AACAAAAACTGAAAGCAGAATCTTGAAGAGCTATCTGCACACCCATGTTCACAGCAGCAT AATTCACAACAGCCAAAAGGTGGAGACGAGCCAAGTGCCCATTGATGGATGAAGGCACAA ACAAAATGTGGTCCACCCACACAATGGAGTATCAGCCTAAAAAGGAAGGAAATTCTGACC CATGCTACAATATGGATGAACCCTGAGGCATTATGCTAAGTGAAATAAGCCAGTCACGAT GTGACTATAAATACCGCATGATTCCACCTACATGGGTCCCTATAGTAGGCACACTCAGAG ACAGAAAGGAGAATGGTGGGTGCAGGGCTGGAGAAGGGGAATTCGGAGTTTTTGATGGGG ACGGAGTTTTGGTTTGGGAAGAGGAAAAGAAATCTGGAGATGGATGGTGGTGATGGCTGG ATGACAGTGTGAATGTGCTTAATGCTGTAGGCTGTACACTTAAAAAATGGTTGAGATGGT AAATTTTATAATATTTATAAATATTATAAATTTATTTATATATATAAATATATATAATTT ATAAATATTATAAATTATTATAAAAAATTTATAAATATTTTACCACAATAAAAAATAAAT CAATAAATATGCACCTCTAATGCTTCCTTCTGTCACTGACATGGTGCCTCTGGACGACGC CTGCATTCTCTTCCCAACAGGCTTTCTCCCGACTACCCGTACATACCCATAAGAGGAAGC CTCTATCAGGGCAGCCCAGGCCCCCTGCTGCCTTTGACTGCTGGGTGCTAAAGTCCCAGA ACAGCAAAGCCCTGCCCCTGCCCAGGGCATCATGCCCCCCACCGACATCAAACAGAAAGC TCCAAGACAGGGCAGAGCCCTGAAGAGAGGGTCCAGCATGACTCCCATGGGGGGCTGACA AGCAGGAAGTCATCCCCAGTGGGAGGACTCAAATCGCCCACTCTCATGTGGGTTTCCCTA CGCTTCCTTTTTCTCTTTTCTGTACCTTCCTGTTTTCTCATTTATTAAGAACATCTCCTA TTTCTTGGTCTTGTACATCCCATGTCTTTTAAAATCACTTATTTTACTTGCTTTTTATTC CCATTTCTCAAAATTCCTGTTTCTATTTTTTTCTTACCTCAAAATTGTATTAACATTTTT CAATTTTAATTTTATATATATTTTATTCATTTTTTGCTCTTATTCCACTCTTTTTTTAGC TATTTCTTTTTACTGTGGTATAAAACACAGTCACATAAAATACACCATTTTAACCATTTT TTTGTTTTTGATACGGAGTCTCGTTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTT GGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCTCCGAG TCGCTGGGACTACAGGCACCCGCCACCACACCCGGCTAATTTTTTGTATTTTTAGTAGAG ACAGGGTTTCATCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGGGATCCGCCCGC CTCGGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACCGCGCCCGGCCCATTTTAAC CATTTTTAAGTGTGCAGTTCAGTGGCATTAGGTCCATTCACAACATTGTACAACCATTAC CACCATCCATTCCCAGAACTTTTTCATCCCAAACAGGGCTCTGTACCCATGAAAAATCCA CTCACTTTTAACTTTCATAATCAAATCCTTTATTCCTTCCTTTTGTATGTTTTTGACTTA TATTTGTGGGGTGTGTTTTATACTGCCCTATCTTAAATTTTATTTTTCCTACTTTGTATT TTATTTTCCCTGTAACTGTTTTTCCCCTGCCATTCTTTTAATCCCTGTTTTAATTTTCAA ATTTTCTTCTCTCCTACACATCACACACACACAGCACACGCACACTGGCTCAGCCCGAGA ATGCTGTCCAGTCAGATGAGCTCCCATCAGCAACCCTTGCCTAGGAAGAAGGCTGCTAAT CCCATGCCATCAGGAAGCCCCTGAGGCCAACCAGGCTGCCTCACGCACCTGGAGTAGACC GCTTCTCCACGACAATACCCAAGGATGGCAGCTGTCTCGGGATAGATGGCCTCATATTTC AGGAGATGCCGCTTCAGGGCATACAGAGGGTGGTTCTTATATAAGCCAATGGCAGTGGGC AAAGGCTGGTCCATGTGTTTAGCCTGAAACTGCAAAGGCCAGACAGACAAGGTTGAGCAT GTTATTTAGAAGAGGAAATGAAGTTTGAGGGAGATGATCCTTAGACTAACTTGTTCTGAC AACAGATGGTGGAGCCAAGGTTTCATGAACACTAATGGTTTTGTAACATCGCATCTGTAC CTCCGGCCAGTAAGTCAGTTACAGATCAATCAAAAGCTTTAAAGAATCAAATAAATCTGT GGCTTGTGGCAACTTCAAAAAGTTGTCTAACCTATTTGAATGCTTAGACACCTAACCCAG CCCCAGCAGATGTGTTAAAGGTCTGCAAGGAAGAAAAACACACAGTGCTCTTCAGTAAGA AGGTCTTATTTCAAAGGGACAATCCTCTTCTAGAGCGTGAGCTTACCTGTCTGCTCTCAC AGGAAACTGAGAGCAGCGGTTCTCACCCTGCGACTTTTCTCTTCGTCCACTATGACAGTG TTCTCTCTGCCCTTCTCTGAGATTGCTCATTTCTCAGTAGGCAATTCACTGCTGTAAGTC ACCCTGTTCACTAGGCTCTCTAAGGCTTGCCCTTGGCATCTCTTCAAAAACCCCAACAGA CTAGAAAGGACTGGCAATGTGGAGTTGCTGAGAGTGGGAGAGGACGCTGCACGTTCAGCT TCCACTGCGCTTTAGGTAGGTTAGTTACGATACCATCTGCATACTTTCCACTTAACCTGT CATTACTAAGTAAAATGAACTTAGTAATGCACCCATTTTACTTAGCATTACTAAGTAAAA TGCACCCCTGGAGCAAACACTCAATATGGGATGCATTGCACTCCTATAGGAAATGATTAA TAAATCTGCAATTTACCTATCCTGAGGGATTGGAAATAAACCTGCGACAAATCTGGGCAT GTTCCTGTGTAGAAATGGCAAGCTCCACCCACCACCACCACTGCCATACACACAGGCGGC TCGGGCACTATTCCTGGTGTCAGTGCTGGTTCTAGGATCAAGTGACATAGCTGTCATGTT CTAGAAGTCTCTGCCTCCCGGTCTGCCTTCTCAATAGACTGAAGATACTGTCTCATTCCG AGACAGTATCATGTCTGTCTCATTCCGAGACCCCTCTTTCCCAGGAGGTGAGTGTTCTAT GTATGAGGGGTGTTTGCACGTACATCTTTACATTCACGCATGATGGGGGAGGGGGGAGAA TATATCCATGGGTTATTCCTTCTTTCACTCAGTCTGAGTTATATTACTTGCATAAATTAT TTTAAAGCTCCAAATTTATAACTGGGCAATAACTAAAAGTATACAGGCTCCAAAGCCACA CAGACCTGGGCTCAAGCACCGCGGCAGTTCATCTTTCAACTCCACAACTTTTTACACTAA AATTAAGGCAGCAACTGCCCCAGCTTTATATGGCTGTGACAATTAAATGAGACAACCCAT TAAAAACACCCAACATAGTGCTGGGCATATATAAGGTGCTCAAAAACAGGAATAATTTTA ATAACCTGACTGTGTCTTGGAGCCCCTGGCAGCCAAGGCCTTACCTCCAAGTCTTCTTTC TTCTCCCTGTCCATAAATGGGCTCTGGTATGGTCTCAAGGTCTCGGCCCACCACTCAGCA TCAACCCGGCACTTGCGGGTCACTGTCATCCAGACTGGGTCGTACCTCTGTGTGACATCT CGGACCCAGCCGTCACTGTCAATGCCCACCACATAGGTCATGGGCTTGGTGGCGTACTTG TAACAGGTCAGAGGCTGGCCCACCACACCGTGCACACAGTCTACACATACCCACTTTTCC TCCTGCTCACAGAACACCTCTAGCCACTGGTCTATACCAGCTATGCTTCTTTTTTCTGCC TTCTCACCATCGCTGCACATTTTCTTGCCTCTTTTACTGCTTGAAGAGCTTGAGGATGCC GCTGGCAAGCTTGGGTCCTTACGATGGCTCCCACGATGGGTCCTGGAGGCACTCTTGGAC CCAGCCTTTGTCCTCTGAGGAGCGGGGGCTTTCCTCTGCTTTGGAGGGCCAGGTTCGGAA TCCTCATCAGAGGGATCAGAGGCTTCTCCACTGGAGAGCTCAAAATCAGAGCCGCTGCCA GCCTCATCACTCCCACTCTCCTCTTTATAAGACACCCTGGAGGCCACCCGCCGCTCCCGG CCATGCGGACGTCGCTGGGTTGCCTTCTCCTGCTTGTCTCCTGGGCCCTCATCTTCCTCG CTGGAGGAGGGCTTGCTCCGTTTCTTTCTGCCTCCCTTGTTCCTCTTCCCTTTGGCACTT GGCCTGCAGGTGCCCTTAGCAAAGGTTTCCTCTTGTTTGGTTCCTTTGCTGGTCTTTGGT TTGGTGTGGTTTTCTAGAACTTGGCTGGAAGTTTCTGAGGAGCCTCCTGGATCCGCAGTC AATCTTTCCTTGGAAGGTTTCTTTCCCTTAAACAGAATAAGAAATTTTGCTTTTTTTTCT CCCCCCTCTTTTGCTAATGATATGATAGAAATCCTGTAATCTAATAGGGTTAAGTCACCA GCTAGAGAACCAATACATCAAGATGTCCCCAGCTCAGACAGTGATCAACCAGCTATCCTT CAGGGTTGTATGTATGTATTGGCTAAAATCTGTAGCATCTTAGATAAGGCCACAGTATAA TTCTTTTCACCCTAACTGTAAAGAGAAAAGAACATGGGATTTGGACAGCCAAACATGGGT CTGAATTCCAGTTCTAACTCTTATTGGTTACGTAAATTAGGTAAATTACTTAACCTCCGA GTTTCAGTTTCCTCAGCAGTACTACTACCCACCTTGGACATACGCATTTTGCAAACAAAT ACTTATGGACTTAATACAGCTGTAGTTTTAAGAATACAGATATTATGAAAATCAGCTTCT AGACCATCAGGCTTCAGACAATGCCAATACCCCAATGAGTACAGCATTTAGCTTCTTGAA GCTAACCCAGACCACCTCAAAATCCACAGTGCTTCACTCATCAGCACTCCACGGAGCAAG CAAGGACAGGCACCATTCCACACAATTTACAGAACAGAACAAAAGCAGCACTGGGCCGAG GCCTCTCACAGGCCACTCTGCACACGTGAAGTTCAGGCTGCTAGATACCCACTCACATGC CCAAGTCTTCCCTAACACAGGGTATGTGCAAGGCTCGAAAGAACCCACACTCCGTGAATA CCAGCTCTTAAAAAATATAATAATGATCAATTTTTTTAAGTGTGACAATTTCCTGTCAAT TGCTCCTCTTCTCTGGCAGCCCTGCGCACCTCACCTTTGCTGTTGCTGACTTCAGAGGAA TTGGCTGTAGAGACAATACCAGCCGGGTCAAGAGCTGCAGAGCCCGGAGAATCAGTAAGA ATATCTATGATGAAAAGGAAGAACATAGTTATCCTAAGAAAGTAATTAAAGATGTAATGA GTTCAATGTTGTTTGTTATGGTGCTTGTTCAAGACAGGGAAAAGCTGGAAACAGCCAGAC TGTCTAACAGTAGGCGACGGAAACTCCAGACACTGTTAAAAACGATGATGCAGAAGTTTA TCTTCGTAGAAGAACAGGAACATGCTCATCATATATTAAAGGAAAATAGAAGTTTTCCTT TAAAAAGTATGATGTGATTACATTTTTATAAGAAAAATATGTATATATAAATTTAGACAT ACACGTATATTTGAAAAAGCATCCATATACTGGGTTATGGGTGTTTACATGCTTTTTTTC TCTGCTTACCTACCTTCTGATTGTTCTGTAGTCAATATGTGTTGCGTTTGTGACTAAAAT AATAAAATGAAATACCACTTTGGGAAGAAGAAGTAGAAAGTATCATTATCGTCAGATCAC CAGGTCTGTTCCCTGTTTTCCAATTTTCCCCACATTGAATCTTTAACTGAGTCTGCAGCT CTGAAAGCTGTTAACTTGGAAGTCTGGGAGCCCCTCAGGGGACTTAACTCCAATGGCAAC AGTGATAATGTACTCGGCCAAGGCCTTCCTACACGGGTCTCCAGGTCCCAGCATCTCTCC TTGATTACTGCCACAGCCTCGGGAGAAAGTCCGGTGTGAGAAGCCATTGTTATGGTGAGA AAAATGATTGCTTTTGCCTTGTTTCTTCTGCGGCTAAAAATTTCCAAAGTGTCAAGGTCA TGAAAGACAGGGAAAGCCCAAAACACTGTCACACACTGGAGGAGACTAAGGAGACATGAT GACTAAATACAAACTGGTATCATGGAACAGAAAAAGGATATCAGTGAGAAAACGTGGAAA ATCCAAATAATGTCTGTAGTTTAGCTGATGGCATTGTACCAGTATTAATTTCTCAGTTTC TTCTTGTACAGCATGGCACAGGAGCACAGGTCCAGAAGTCTGGATAACTAAGTGTTCACC ACTAGCTGAGTGACTTCCCTAAGCCTGGATTTCTGCATCTAGAATAATCCCTGCCTCGGC TTCCTCACAGGACTCTAAAGAGGATTAGACAAGATAATGCAGGTGACAGGACTCTGGAAA CAGTCTAGTGCTACCCAAGCATACACAGTCACCACCTTTAGTAAGAAATCTATCAATGTA CATTGCTGAGGAAAAAAATCAGGTTACAGAACTGTACGATCCCTACAAATTAGATAACAT AGAGAAAATGGACAAAATCCCAGAAACATACATATATGACCAAACCTGACTCAAGAAGTA ATGGAAAATCTGAACAGATCTGTAATAACAGATCGAGTCAGAACTCAAAAACCTCCCAAC AAAGAAAATGTCTAGGACTAGATGACCTCACTGGTGAATTCTAGCAAATATTTAAAGTGG AATTTACCTCAATCTTTCTCCAACTCTTTCAAACGTTAGAAGAGGAAATATTTTTTAACT TGTTCTATGAGGCAAGCATTACCCTGACACCAAAGCCAGACAAATACATCACAAGAAAAT AAACCAATTTATGAATATAGATGCAAAAATCCTGAATAAAATACTAAAAAACAAATTGAA CATATGAAAAGGCTTATACAACATGACCAAGTGGTACTTATCCTAGGAATGCAAGGATGG TTCAACATAAGAAAATCAATCAATTAAATATACATTAATAGAATGAAGGAAAGAAAATCC AGAGGATCATTTCAACTGACAAAGAAAAACGCACCTGAGACAATCCAACAGGCTTTCATG ATTAAAAAAAAAAAAAAAAAATTCAGAACACTAGGAATAGAAGGGAACTGAGTCAACGTG ATAACCCAGATCTAGTATGATACTTAATGGTGAAAGATTGAGAGCTTTCCCTCTAATTAT CAGGAACAAAACAAGGATGCCTGCTGTCACCACCATTATTCAACATTGTACTTGAAGTCC TAGCCAGAGCAATTAGGCAAGAAAAAGGCATGCAAACTGGACAGGAAGAAGTAAAATGAT CTACTCATAGATGGCATGATCCTATACATAGAAAATTTCAAAGAATGCACAAGAAAGCTA GTAGAGCTAATAAATGAATTCAGCAAAGCTGCAGGGTACAAGACAACACAAAAAAATCAG TTGTGTTTCTATACATTTGCAATGAACAACCTAAAAGAGAAATTAAGAAAACAATGCTAT TTCCAAGAGCATCAAGAAGAATAAAGTACCTAGGAAAAAATTTAACCAAGGTAAAAGGCT GTACACTGAAAATTACAAAATACAGCTGAGAAATTAAAGACAAAAATAAAAGGAGAGACA TCCATGCTTATGGACTGGAAGACCTAATAACCAGATGGCAATGGCACCCAAATTAATCTA CAGATCAGTGCAGTCCCTATCAAAATTCCACAGCTTTTTCACAGAAATGGAAAAACAGAT CATCAAATTCATATGGAATTGCAAGAGGCCCCAGATAACCAAAGCACACTGTAAATGAAC AGAGTTACACTGAGGCTTCCTGATTTCGCAACTTACTACAAAGCTATAGTAATCAAAACA GTGTTGTACTGGCGTAAGAACAGACATGTAGACCAACAGCATAGAATTGAGAGGCTGGAA ATTAACCCATACATTTATGGCCAGTTGATTTTTGAAAAGGATGCCATGACCATCCAAGCC CCATTGAAAAAATTGTCTCTTCAACAAATAATGCTGGGACAAATGGATATCCACATGCAT AAGAATGATATTGAACACCTACCTGATATATGCAAATATTAACTCACAACGTATGTAAGA GCAGTAACTATAAATCTCTTACAAGAAAACACAGGGGTCGATCTTTATGACCTTGGATTT GACAATGGAATCTTAGATACGACACCAAAAGCAAAAAGAACAAAAGAAAAATAGGTAACT TGGACTTTGTCAAAATTCAAAACTTTTGGGTATCAAAGGACTTCATCAAGAAAGTAAAAA GGCAACCTACAAAATGGGAGAAACCATGTGGAAAGCATGTATCTGATAGGTAACTAATAT CCAGAATATACAAGGAGCTCTTACAAATCATCAACAAAAAGGCAACATAATTAAAAAATA GGCAAATACTTGAACAGACATGTCCTCAAAAAAGATACACAAATGACCAAGAAGCCCATG AAAAGACACTCATCATCATGTCATTGGAGAAATGCTATCAAAACCACAATGAGGTATCAC TTGACACCCATCATAATGACTATAATCAAAACATCAGAAAATAACCAAGTGTTGGTAAAG ATTTGGAATCCTCGTTCATTGCTGGTGGCAATGTAAAATGGTACAGTAACTGCAGAAAAC AGTTTGGTGGTTTCTCCAAAAATTACATATAGAATATACATATGACCTAGCAATTTCAAT CCTAGGTATATACCCAAAAGAACAGAAAACAGGGTATGTAAATAAATATATGTATAGACA TTATTAACAACACTCTTCACAACAGCCACAAGGTGGAAACTAACTAAATGTCTGCCAATG GATAAATGGATAGAGAAAATGTATAAACATGTAATGGAATATTATTCAGCTATAAATATT AATGAAATACTGATACATGCTAAAATGCAGATGAATCTTGAAAACATTATACTAAGCAAA AGACAGGCAGAAAAGGCCACATAGTGTATAATTTCTTTTATACTAAATATCCTAAATAGG TAAATCCACAGAGACACAAGACAGATTGGTGGTTGCCACGAGCAGGGACAGGGGGGTAAC AATGAGGAGTTTAATGCGTATATACAGGGTTTCCCTTGGGGGTGACAAAAACATTTTGGA AATAGAGGTGGTAGTTGCACAACATTGTAAATGTACTAAATGGTCACTGAATTGTACCCC CTCTTTAAAAGCTGTGTGATCCTATTTTGCTTAAACAAATAAACAAAACAAATACATACG TACACACATACACAGGAACAAAGTCTGGGAGGACAATACTAAAATATTAATGAGTTACCA GCCTGGCCAACAGGGTGAAGGGTGAAACCCCATCTCTACTAAAAATACAAAAATCAGCCA GGCATGGTGGTGGGCACCTGTAATCCCAGCTACTCGCGAGGCTGAGGCATGAGAATCACT TGAACCCAGGAGGTGGAGGTTGCAGTGAGCTGAGATTGCACCACTGCACTCCAGCCTAGG CGGCAGAGAGAGACTCTGTCTCAAAAAACAAAAACAAACAAACAAAAAAATTGGCAGCAC ATTATAACATAATTATCAGCCTTGCCAAATATCTTAGACTTGTTAAAGCCAACACGGAAG AAGAGAACTAAAGATGTCAACCATCTTTTTCTCCAGAGAATCTGGGACTCCCAGATTGAA CTGTATGGATTAATAGGAATCTTCTAGGGATAAAACCACATTTCCATCTCTGTTTTTGTT TTATTCAGACAGAGCCTTACCTACAGGTGCCTGTAGGCATTTGATAAAGCCTGCCTGTCC CTGGAGCACTCTGCCATCACGATTCCTTTTTATGGACAGAACCCTCCTCACTGCACTGCT GCCTGCCAGTGTCAACACCCAAATGTGAGATACAAAAACACATTCTCAAGGACTTCAGCA TCCAATTTGAAAAAACATTTCCTTGGGACTTCTGAAGACAAAATTGGAAAAATTAATGAA AATATTTCTAGCACATCTGACCAAAAACTACGGGCTTTTTGGTACACCACAACTAGAGGC GATAGGGAGGAAAGCATACAGGCCCTCCACTCAGACTCTGATCCCAATCTCGATTCTCAG GCTCACCAAGGAAAAGACCTTAGAGGCATCATGTAGCTATTCTGGGCTTCAGCAGCTATC AACGTCATTATGAGGACTGAATAAGGTAGTGTCGGTAACACACCTGGAATGGCATCTGGC ACATGGCTGCCATTATCATTAGTTAACAGTACTGATAAAAAACAGTGATCCGGGAGGATC ACTTACATGGACCAATTCCTCATCATCTCGAGCAGAGTAAATAGCAAATCTCCTTTCCAA TGTAGTCTGCAGGTTATCTTGTTCACTGGCTGAAAGTTCTGCATTAACTGTAAATGTTCC AATGAACCTGGGGAGAAAGCAGGCATTCCTTGTGTCAGAGGTCAGGGCAAAGGGGAATTT TCATTTCCAGCCAAGAAAATAAAAAGAGGGAGTGAATCGTGAGACCCGCCTGCCTCTGTC CTACTTTCCCCAGCCCGTCTAGCTAACTCCTATCATCACTGCAGACCCAGCTCAGACTTT ACCTCCTTGGGGAGCCTTCCCAGACCTCCCAGCTGAGAAAAGCGCCCCTGCTATGTGAGC CTGCAGTCCCCAGAACACCCCTTCCAGGGCACTCCTCATGCCATCCTGTAATTACCTGGT ATGTATTTGTCTCCCCACCAGTCTGGCAGCTCTACCAGGGCAAGATCATACCTGGCATTT CTCTATCTTCAATGCCATGCCCACCACCTGATACATAGTTACCGCCTCAGGGAAGGTCTG TGGAAGTGACCTGAACCCAGCCTCTGAGAGAAACACAAATCCTACACTCCCCAGCTCTGC AGGACAAGCGGAGGGCCTTACCACTTCACCAGGTTTGAGAGGTAGTAGGTGTCCACATCT CGAGGCAGCACTCTGGTAAAGCGGGCTGGGATGATGGACAGGCCAATAGCATGCAGATCT GGCTGGCTGCAGATGTTATTTCGATAGAAGCCATTTGCTAGCAGGCAGAGAAGGTGAACC TGTGAAGAGGAAAGGAGGAAGGGGCAGCATGGAAGGAAGGCCGGACACCAGGAGGAATTT TTGCTGCCAAAGTCAAGACATGCTGTGGACAAGAAATATGTGTTGCCATTTCTACATATA AGAAAGTAAAAACACTAGCATTGGCCACTTCCCAAGCTTGTCTTTGACCCTCTCTTTTTC TCTCTGTATACTCATTCCTTCAAAGGAATCATCAAACCTCAAAGCTTCAAAATACAAATT GCTTTGTTTTCAAAATACAAACTGTTTTTGTTTTGGTCTTGTCTTTCAGAGATACATACT GAAAGATTTCTGGATGAAATGCTGCCATGTCTGGGGTTTGCTCCACGAGATCAGAAGAAA AGGCAAGTGGAGTGGAGCTGGAGAGACTGCTGGAAGCCTGTGGAAGCCGGCGGGATGCAC CCCACTGGGCTCACTGGGCTGCTCTCGCCACCTCTCTGGGTGTTTGAGCCCAACCTTCTC TGTCACAGGCTCCACATCTTTGCCCTTCCTCTGACCCCAAAACCCACCCTTCATCCACCT ACTGAAATGATTATATGACCTCTTCACCTCTTTTCACATACTGCTTTGTGTCATTTTCCC TTCAACATTGGCTTCCTCCCCCCCGACTAACAGCCTCCCTATTTTAATCAATAGTGCTGC CTCTCTCTCCTCACTCAGGCCTCAAACCTGAGAGTCATCTTCCCTTTCTTTCACCTCCAG CACCCAACAAGAGGTGAAAGGCACACAGCTGTCTCGTTTCGTGCCCCAGGCCTGGGTGAG GGAGGCGACCCCTCTCTAACCTCGTCACCATCCTTGCACCTCTAGATTTCTGCAGTAGCT GCACACAAAGCAACTCACCCATCCCATCACTATCCTCTCAGGCAGCCCACCATCCATCAA AGGGAAACCAAAGCCCACCCTCCCTTCACCCCCACCCCCCAACACCTACATACTCCACAC ACGCAGGTGAGCTGGGCACCTCGCCGTCCCCTCCACAACTTGGCTAGAGTCTTCAACTTT TTCTCCTAGACCTGGCTCTAATCCTTTCCCCTACATAAAGCCTTCCCCAGCTCCACAGAG CCACGCTGATCTCTTTCACTGTTCCAGGCATAGCCTTGAGTTTCTCTGTTTGGAAGTCCT TGTTCCATCTAGAGATCAGATACTCCTCAATTGTAGGAAATAAGCTTTATCCAAGTCTCT ATCCCCACCATGCCAAGCACCTTGCTAGGTGTGTGCAAGTGTTCAATAACTGTCAGCTAA AGTCAAAAGCCAGTGCCTGCAGCTGGGATTAGAATTAATGACATTAAATGGCTGAAAGGA GAGATGGAAGGCAAGTGCTCTTTATTTAGCCTCTGCTGCATGCCAGGCATTGTGCTGCAA GTTACCTTACCTATAATACACAACCACCCTCCAAGACAGACACTATTACTACCCCCACCT CCCAGATGAGGATGCAAAGGCTCAGAGAGAGTAAGAAACTTGCCATGGCCACAGAGCAGC AAAGCCAGAAATAAAGCCTCGGTGAGCACAAGCTCTTTGCACCGACAAGGAAAAGTCCTT CCCCATCATTCCTTGCCCTTACCTTGTGTGTGTCCTCATGGACCCCTTTATTGAAACGTT TCATCGCCCTCCGAAGATATGTCTCAAACTCCAGTTTTATCTTTTCACTGCAACAAATAG TGAAAAATCTGGGAATGAAGGGGGGAACTGAAACCAGACTCCACTCCCCCAGGCAATTCC TTCTCCTCGGATGACAGTGAATCACTCTCCCTGTTTCCCTACACAAGGCTGTGCTACTCA AGTCCGTCTGCAAGCCAGCTATTTCCTGCAGGCTCTTTGGCTCCTTCTCACCAGCAAACC TCGGCCTGGGACATTCTGTACCCAGACAACCCTCCTCTCAACCAGCAGCAGATCACACCT CACCTACATGCCTCAAAGCTCACTTCTTCCAGGAAGTCTTCTCTGGCTGTCCAACTCTTC CGACTACTGACTCTCTCCTTAGCAACCATTACCTTTATTAATGTTAAATTAACACACCAT CATTTATGTGACACTGTTCTAGTGTAAAATCTCTTTTTCAGTCTGTATCCCATTAATCTT CAAGACAACTTGACACTTCTTGAATGATTTGTATTATCTCCCTCTTCTGTGCCTAGTAAT GTGCCCATCGCACATTGGAATTCCCAAGCCATCAGAGGCTGCAGAGGTACTCCGGGATGC TGGGAAGGATAGGGGCTCCCTACCACGGCGGGCACTGCCTCAAGTCCTGCAGCATGACAT GGTGAGGAAAATGTGAATGCCAAGTCAATGAGAAGGATTAGGTCTCAGCTCTTCCATTAC TGGCTGAGTGACTCTTGAAACGTTACTTAGCGTCTGAACGTTACTTAGCTCCTCATTCAC AACACTGTTCTAAGGATTAGGTAAGATAACGGATGACCTGCTCAATCCTTGGCACACAGG AGTTCCCTCTCCTCATCCCTCACCAGCCCCAGCCAGGACACGAAGGTGTCTCATTCAAGT CTCTAAAGGTAAATCAGGTTCCTGACCCAAGGTTCTCGACCACTTTGATACTCAGTCCTG GTCCCCTACAAGTTTCTCCAAAGTCCTCCTAAGCAGCAGCTGTTGCCTACTGCATGTGAC AGGAGCCTAGAAGCAAGGGCCTAAGCTTACCTTCTTTCTCTTGTCTTCGCCTGCTCTGGC GTTTCAATCTCTATCTCCACTGGCTTCACAGGCAGAAGAGATCGAGAGAAGGCTGTACTT TCTCTCACGTCACCCAGCACAGGCTCACTAAGTTCTATCAACAAGCATTTTTAAAAATCA GTAATAGTAATAACAATAATAATAGCTACTGTACTGAACAGAATCAAGGTTCTGCTGGGA AGGAGGAAGTGAGGCATGAATGTGAGGGAGACAGCCCACAGAGACCCCTAGACATGCCTT GCCCTGAGTCCTACCATGTGCCGGGCAGTGTGCTGAGTGTTATATATTCGTGTGTCTCAT TTAACCCACACAACCCAGACAGTCTTTAGATAAAGAACCTAAAGCATAGAGATACTGGGT TGAATCAGATACAGACCCCTCTATCAAAAAGCTGACACTCATGCATGTATGTATATACTT AAAACTCTTTAAAAAAAAAAAACCCAAGTGAGAATAATCTCCTTTTCTCTGTATTCTGTA TTACCACAATAACAATTAGCACAATTTGCTTTGTATAGAGTCATGACTCAGGTGTCCATC TTTCATTCTCAATTATAAACTTGTAAGTGACAAAAAATATATCCTTTTCATCTCTTCACC CCCTACGTTGCTTGTATACAGTAGCTGAGAAGGACTGAACTTGCTGAACTGGATCTAATT GAAAACTTCATTAGCAAAAGTTCCTTAAAAGAGGCTCTGGGCCTAGAAGCCATGACATCT TACTGGCAAAGAATGCATCTAATGCCAGATCTTGGTCTCTATACATGAATCTCTATTAAA ATGAACCACAGCTTCTTGAAGAAAAAAAGGCTGGTTTCAAGTCTACAGCAAGAAAAGTAT AAGCTGAACAAAAATGTTCTCAAAGACTAATGAGGCCATGTCAAAAGGACATGGTAGTAC AGCTAGCTTAAAGGTAGCATGACTAGAAGAGGAACAACCTGACATTAGAGGTGGCTTAAT CAATGCAAGATGAGGTTTAAAGCATCATCTAGGAAGGATTCTTGGAAAAAAAATAAAAGT TTAATCAAAATTACATGTCTTTGGACTTAGTTTACAAGAAATACAGGGGATATTGAAACA AGTTTAACACCACCATGAGATGTGTGACTGTTTATCAGACAAAACTAGAACATGAGACAG TCTACAAAACAAAAGACTAGGATCCTTCAAAAAAGGCAGTGCTATGAAAAGCAAAACAAG GCGGTAGGTGGGAAATACTGCTCTATATTAAGAGAGTAAAGTGACATAAAGACCAAATAC AAGGCTTGGTTGGATCTTGGTATGGAAAAAGAAACAGGCATAAAGGATGCTTTCATAACA ATTGGGGACTTATTTTTCATTTTCGTAGGTGTGATGAGGTCATTTTGTCATGCAGGAGAA TGTCTAATTATTAGGAAATGCAGGCTGAAGTATTCAGCAGTGGAGTATCAGAATATCTAC AACTTATTTTCAAATGGTTCCACAATGAATATTTACAGAGAGAAACATACATTCAATGTG GCAAAATGTTAATGAACCTAGGTGAAGGACATATATTACATTTTTCACTCTTTTTATAAA TTTGAACACTTTCAAAATAAAAAGGTGAGGAAAAGTCAGGCCAGACAGAAGGAATCAGGG ATGATAACATTAGCTGGTATTTACTGTGAGTGTATGATACATTAGGCCCATTACATTTGC AAACTTTCTTTTCCCCACAATAATCCTACAGCCTATACTGTGAATGGCTCACACTAAACA TTCAGTGTTTACAGAGTGTTACCAATGAGAAAACTCAGTTCAGAGAGGTGAAGTTACTTG CTCAAGATTAAATTACTCACTCACACTGCCACCTAAGTGGCAAAGTTGAGCACTGAACCC AATTCTAACTACTTTCAAAGCCTGTGCTCCTTCTCCTAAATAGTGCTGCCTCTCTATTTA TATCTACCCCATTGACAGTCACCAGAGGAAGAGAGTAAACAGCCTTCTTTGGTAACTTGG CCATGAGTTTTTCCATATATATCAAAGCAAGTCCCTAGTACAACCTTATCTGTGGTCTAA TTAGCTCAAAAGAAAACAAAAGGATTGCAATTAGTGATCTGACTCCAAACAGAATCAAAC AAAAAAACAAACAGAACCAAACAGTTCTGAAAACAAAGAAAGATGTTTCACCTTCAACCT CTTCCCAATCATTTTCACTTTCTTCCTCTTCTTCATTGCTGTCTTCATTCATGGTAGCCC CTCTCTTCAGATGGTGTGCCTTCTTGAGGTCACTTGGAAAGTCCCTGTGTAAAGACCACA GGAAGGAAGATGAAGAAGACTCAGACATCCTAGTGTTCCATTCAAGCTAAATGGAATTTT TAAAACCCCTCCTATTTATTGAGAATCTGTTGCAACTATTTAAAGATGATTAGTAAGCTC TGAGCCTCACTTCCTCCATCAACATGTGTTCCAAATCTCATCAAGATGTGCTCTGATCAT CTGTCTAATTACTACCAGATGTGCTGTTAAAAAACCTACAATCTAGATCGTGTGAAAGAA AACATAGCTGTGCCTGGACATGACAAGGAAAAATTAGAAGACACCAAAATAATAATGAGT TCCAGAACTGTGATATCTGTGTGATATATGTGCAGTTGGAGGCCAGAAAGAACAGAATAA AATCTCCATTTATATATCCTACTATAAGCCTACTCAGACTTCTTTTCCATCTTTAAGAAA TATGATGTAAGGAGACTGAAATTCATAGCATTCTAACTTCAAGCAGGGATGTAACTACAC ATAGGTGAGTCATAAATAACAAGAGACATAGACAGCTAGCTAGCTAAGTAGATAATAACA TAGATAAGTAGCTGGCTAAACAATGGCTCAAGGCTAAGTACTTGCTGATACGTAATATAT TTCTGCAAATTCATATATAAAATGTGTCTAGAGTATCCAGTTACTTTTAACTTGTGTAAA CTTTGGCACTTGGTACCAAGTGAGAATATTATCTAGGATTTTGGTATAAACATTTAAAAT AACCAATCATCAATCTTGAGCTCTAATAATACACTCTTTTTTTAGAGTACCACTTTCTCT CAAAACACCAGCAATAAAAATTTCCCCTTAGAATGAACATAGCAGAAATGACCACAGTCA ATGCTCAGGGGAGAGGGAAAGGGGGACCCAGAGCTTTCCTTGGCAGTATCGTGGCCTATC TCTATGTATATGTCTCTGGAGATAGAATTCAACTAGTGAGGGGAGGCAACTGGAAAGCAG TAAGTTCAGAGGTATTCTTCAGAAAAGTCTAGGGAAGGCCAGGCGCAATGGCTCACGCCT GTAAGCCCAGCACTTTGGGAGGCTGAGCAGGGCAGATCACCTGAGGTCAGGAGTTCGACA CCAACATGGTGGAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGG GCACCTACAGTCCCAGCTACTCAGGAGGCTCACTTGAACCTGGGAGGCGGAGGTTGCAGT GAGCCAAGATTGCATCACTAGACTCCAGCCTGGGCAACAGAGCGAGACTCCATTAAGGAC GGGACCGGGATGGGGACGGGACGGGGCGGGACGGGAAGGGAAGTCTAGAGAAAAGGAGAA GAGATGGATCATGGCGGAAAATCATCATGCTGTCCCGTGTCCCTTCCTGTGCCCTCTACT GGACTACTCTCCCATCCCAGGACTAGAGGCTGCTGGAAAAGCTGATACTGGCAGTGAGGA TTTGTTTATGAAGCAAATGAAAAACTATCCCTCTGTTCTTCCTCTTCTCCCCACCCCTCA ACTTTCTTAGGAGGCAGAAAATCAAGTGTTCCCTGGGCTCATAATCACTGTTCACAACAT ATTAATATAAATGCTCATTCATTGCAAAAATACTTGTTCAGTTTCTGCCAAATAAAAGGG CCTGCAATGGATGCTACAGGGCATATGAAAAGGAACCCCACATGGTTCCAGCCCTCTGAG AGGTCACAGGGTAGTAAGCCTGGGTATGTGGCATGGTAACAATAACTGGCAGACATATCA CACTCCCTAGAAGCGCTACAGGAAGTCAGAGGAGAGAAGGGGGAAGAATCAGTGAAGCCT CTGGAGTAGGTGGTTTCAGATCTGCATCTTCAAGATGGAAGCCAGCAAGCACTCCAGGTA GAGGGAATACCATGAGCACAATGCAGGTGTAGAAAGTAGGAGAATGTGTTCAGTGAATGA TGAGAAGCTCAGGTGGGCCGGAGAAGAGCGTGCTTGAGGACAGTAGTATGAGATAAAGCT GGAATGGCAGGTAAATATTTTGTATACATCTAATATTTTTGTGTAGTAGAAAGAGCACTG GACCAGGAGTCAGAAGACCTGGGTTCTCCTGCTTTTGCCACTGTCCAGCTGTGGAAGCAT GAATAAATCACTTACTGCATGCTGTCACTGTTCTTATCTGAAAAGTTTCCAGCTCTTACC GGTCTGAGTTGTACCTAGAAGAATTTAAAGATCCAATCTTCCATGGACCCCAGTGACAAG TAAGAATAGAGGTTTTCATTATTCACAATTCTCTGATGAGAAAAATCAAGACCCGAGACA AAGCTTTGCAGACATCTCACCTGAGGTCATCCCCATCGCTGAGGGCTTCATCCTTTATAA CCTTGAGGTTTTCAGATTTAACAGTCACCTTGGCCACTTTCTTTTTTGCTGGACCATCTG CTGAACCCCCAGGATGACTGCAGCCTCTTTTCCTCTTTCCTTGTGAAACTTTGGAGAGAA GGCTCTTCTTTGGGGGTTTCTCATCTTCAAAGGCATCTAGGTGACAACACAGAACATAAG GTGAGGGGTGGAAGGAAAGGTGGAGGCAGTGCAGCTTATGGGCAGGGGCATAAAACGGCT CTATGACCTGTCTCCAAACCCCATCTCCATCACTGGTTCACCATCCCCTGTCTGGTCAGC AACCAGCTCTCAGCTTCTTCCCACCTGCGGCTAGTCTATATTCACAGTAAAAACCATCTT CCTTTATCAGCACTTTACTTCTCCTATGACTACAGAAAATACCATAGGACTCAAATAAAA CCTAACTTCCAGATCTTAAATGTCAGCTAACCTCCTGCCAGGAAAATACAACATCCATTA ATTAGCACCTTATTTATTATCTGCCAAAATTAATTGTCTTAGGGATAATGTACTCCTAAG TAAAATGTTAAGTACATAAACATGTCCAAGTTTTACCACAACATCATTACTATTAATCTA CATTTCTGCCAACCTTCAAGACCAAACTGCTCAAAACACATACTGCTCTGAAACCTTTCC AATGTAACCCAAATGGCACTCATATACCAACCACCTCAGCAAACTTACAGTTGGAAAAAG ACAGCAATAATTCAAAAGTATTTTCTTAAAGTAATTATTTTTTTGTTAAAGGGAAATAAA AAATGCATAAGCTGCTGGTTTTAGTCAAATTGGGGTATCTAAAATTATGGTTTATTTACA TATAATAATTATATTAATAGATTAGTTTTAACAAATAATATGGCAGGGAAGGATAGTTTT CTATTTTGCAAATATATTCACACAAATTATCTTGAATCTGAAATAAATCTTTTGTCTTTG CATGACTCTGCTTCAATTAATTTTAGAAAATAAAAATACTCTACCTTTTATTGAGGTTCC AAAAGGGATTGCAATATTAACCTAAAATATAAAATTATTTAATAATTCAGTCTTTTCATT GTTTGTCTTGCTGACTCTCTGGATGGGTATTTATATTCCACAAGAATATACTTTTGCATG AGGGAAAAAAGACTCTCCCTTCTGATCTAAATGAAATCATGATTAAATGTTAATAAAATT CATAACAAAGGAGCATTTATTTTAATGTTAGATCATTGATTCCGTTGTTTCTTTAAATGT TTTATAAAAAAGGAATTTATGCATTCCCATTTTTAAACATTGTATGGAAACCAAAAAATA AGGAAAAATTTTGAAGTACAAATTATTTCAAAATTAATTTTTTCAAATCTGAGAACAGAT TGCCTACTCCAAGGCCAGAGGTTGCATAAAGCTTAAGATTTGACAGTTTGAGGAGGGTGC CCCTAAAATCAAGATTTCTGGATCTTACAATGGTAGTTAGCCCTCTAATAATAGGCAAAG ATGCTAAACACTTCAATTTCTACTAATCTAAAAAAATGCACGTAGGAGGATACTTCAGAG GCATCACAAACTTTTCTAGTTGGTTAAAAAGCACAGCTTTTATTTCCGTTTGAAGAGAAA GGTAGAGGAGTTAAAAGGGAAAGGGGGATAAAGGAAACACAAAAACTCTGAATCAAAAGG ATGTTCATAGTATTCAAAAGCATCTAACAATAATCTGAATGTCCAACCATGAGATAATTG TTAAGTAACTTATGGCAGAGCCACACAACAAAATATAATTGAGTCATCCTTTAAGATAAA GAAAAACGATATATGATGTAATGTTACTCATGCAAAGTTGATTTTACAGTATGCTTTCTG CTATATAAAAAACAGACTAGAAGGAAACAGACCACTATTTCATGGTGGCTATTTCTGGAT GGCAGAAATATGGGTGACTTTCTGTTCTCTGCTATTTTTTGGTCCCTAAGCATCTAGAGA CTCTTTTCCAGGACTCTCCAAAATCTTGAGTTATCTAATATGCCTAACCAGACTCCTTGA GTTCAGTGTTCTTTCAGTAGGGCAGGAATTACCACTGTGGTCTGCTTGCCCATCTACTGG GATTTAATAAGAACACCGGAGTAAACCTTCCAGCAGCAACTCATAGCACTCAGAATAAAA TTCCAACTCCTTAGCTTGGTATCCAAGCTCAGGCCCTTGCTCACTTCTCCTACCCAGCCC CTCGCTCGCTGTGTCCAGCCAACTGGCCAAGTTCATTCCCTCCTAAGAGTGTTTAAACAC ACTGTTCTCTCTGCCTAGAACTCTTTTCCCCAGAACTTCCTATGAATGGCTCAAAATTAC ACTAAATGCCTCAAAATGCCACCTCCTTACAAAGGCCTTCCCTGACACTGATTCCCATTT AGCTGCCTCTCCCCCAGCCCCATATAAGTTTGAGGGTTTTTCTTTTCATCTATAGAAGCA TTTTCTGCTATGTACCCAAATAAGTTTTATCACAGCAGTCTTAGCACAGGGTGATAGCTC TTATCATCATGTGAATCCGTTTTTTTTTAACTTGTTATCTGCTCTAAGTACCCCTCCCCC CAGATTATAATCATGAGAGCAGGTGCCTCATCTGTCTTGTTCAATATTATCCTAGTACCT GGAACAGTGTGTGAAAATAGTAGGCGCTCAATAAACAGCTGTTGAAGGAATTAATGGATA TCACTGAAGGTGTTAACACAGAGAAGAAATGAAAAGAAACCAGAGGTGCTTTAGTAACAC AAAGGAAATCATGTGGAAGCCTGTTTTCTTTTCTCCTATTTGTCAAAAGCAGCCAAGTAT CACCTTCATTTGCATGTACAGGGGTGCTATTAAAACCTACACTATTACAGTGTTAGCAAC TACACTGACAGTCACCAAATTATTGTCATCTGCAGCCCAAACCATACTTGCTAAGTCTAT GCTTCCCCACAAAACCACCAAACCACAACAAAGGTTGTAACTCTGCAGATCCTGGAAGCT GCCTTGGGAACTGACTGCTAGCTCCTCTGGCTAGCAGAATAAACTTGGGTGCATCTTTAC CTCCGTTTAGGCTGAATGACACCAGCTAGCCCAACTAATTTACCTAACATGGGTAAAGCT AAAGCTCTTGGCTTTATATGCTATCCCACTGAAAACTCACAGCCACCCCGCAAGGCAGTT ATTACATTTCACAGAGGAAATTCAGAAGGGCTAAAACATTTGTCCAAAATAATTCACCCA AGTGCATAAAACTAAGAATTGAAGCTCTACCAAGCTGGAACCGAGGTGAAGTGTTGAGCT GGGAAGAATACAGGTAGCATTTCCATCAGATTAAAACCGTAAATTTTTAATTGCCATATA TCCAAATTACATTCTGACTAGAATACCGGCCCCTTTTTGTGACCCCTTGCTAAAATACCA ACCATCCTTTAAATCACAGATCAAACTACTTCAGAGAGCGTTCCCCGATCACGCCAGTCA AACTTGATTAATCCTTTGGAAGCTACAAAGCCTTGTACCTTCTTCCACAATATTTAGCAC ACTTTGCCTTGAATGTTTTACATGTAAATGTCATGTCAACACTACTCTATGATCCTCCAA GATATGTTTATCTCTCATGTCACCTCATTCATGTACAGCACATAGTAGATACTCAAAAGA TGTTATTTGAATGAGTAAATGAGTGAATAAAATGGAACTCGTAATATTACATATGAGGTA AATCACCTCCTAAGTTTACGAATTATTACCATTTCACTATTTCCTAATGGATGATGAATT TATAACCGGTATAGAAACAGAATCTAGTGTGATAGCCTTTGCCGGTTACCTAGTCTAATC TACCCAGTTTTTTCAGGAGACCCAGAAATTCCTTCTACAGCCTGCATTTTGCAATTATTT AAAATATTTACTAGCCGGGCGCAGTGGCTCATGCCTGTAATCCCAACACTTCGGGAGGCC GAGGCAAACGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAAC CCCATCTATACAAAAATACAAAAATTAGCCGGACATGGTGTCAGGCACCTGTAACACCAG CTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCTAGGAGGCGGAGGTCACGCCACT GCACTCCAGCCTCAGCGACAGAGTGAGACACTGTCTCGAAAAAAATAAAAAATAAATAAA ATATTTATTTAGCATTTAGCCCTACCAATCCACGGGCCCTGCATCCACAGATTCAACCAA CCACAGATGAATATATTTCGGGAAAAAAAATACAAATTTAAAAAATACAGCATGACAACT ATTTCCATAGTATCCACATTGTATTAGGTATTATTAGTGATCTAGAGATGATTTAAAGTA TGTCGGAGGATGTGCATAGGTTACATGGAAACACTAGGCCATTTGATATAAGGTACTTGA GCATCACAGGTTTTAGTATCCGCGGGGTATCTGGGAAGGACCACCTTAGTTTGCTCAAGG AATGTCTAACTTGAGTTTTGAAGAAATAGAAAAAATCAGCCCTGGTAAAAGCCATGGGGG GTTCACTCTAGGCAGAAGGAACATCAAAGGAAAAGACTCAAGGAATAACTTGGCATATTT GAGGAAGAGAAAGGAGGCCAATAAGGAGGGTATCTGGCAAGGAAACAAGTGGTAAGAGAA ACAGGAGAGGTAGCAAGAGCCAAAACATGTAGTATCTTGTAGGCCAGGATAAAACAACTG GATTTTAAGCTAAGAGCAATGGAAAACCAAGGGGAGTTTAAAGCAGGAGCAGGGCATGAT TTTTTTTTTTTTTAAGATTATTTGGGTTGCTGGATGCAGAGCTGGGAGGCCAGTAAAGAG GAAACTGCAGTCACTCAACTGAAAGGTGATGATGACTTGGACAGGGGCTGTGGTCATGGA AATGAAGAGAAGTGGACAAATTTGAAATACACTCTTGAGGCTGAACTGACTGGACTTGCT GACGGACTGGATGTGTGGACATAAGAAAAAGGTGGGCTTTGCTTTATAACAAGTATTGAG ACTGGAAAAACGGAGGAAAGCATAGATTTAAAGAGGAAAACCATGAGTTCTGCATTGCCC ATGACAAATGTAAGAAGCCTATCAAATATCCATGAGGGGAAGTCAGGTGGGATCCCACTG TGGAACTCTGGGTGAGACTCAGCTGAAGTTATCATTCGGGAGTCAGCACACTGCATCACT CTACGTCCTGGTCCGTCCGTCTGTCTTCCTGGGACACAAATAACTGCCTTCTCCGAGTTC AACCCTGAACATCTGTATCCTCTGGACAACGGGGAGCGGGAAAAAAGCTACGCAGGAGCT TGGATCGGGCGAAGCTCGCGGGAAACCGCTCTGGGTGCGCAGGACAAAGACGCGGGGACA GCGGGGAGGGCCGGCCGCAGCCTGCCGGGCTGCCCCCACGGCGCGGAACGCGCGCAGCAA CCTCCACCAGGCCTCCGCGTCTGGACTCCCGCCCTGCCTCTGGGCCTCCTCCGCCCACCG GCGGCGTCTCCCGCGAAGCCCGCTGGGCCTCGCTCTCACCCTCCTCCTCCTCCTCACGCC GGGCCTTGCTCTTGGCCTTGGATTTCTGGCTGCGCAGTTCGCGTCCCCGCGGCTCCCCGC CGGCCGCGCGTTTCCGAGCCATGTTGCTTGTCTGGGCAAATTCCACTTCGCGAGTGACGC ACCCGGCCGCGATGC bcftools-1.21/test/csq/ENST00000285021/ENST00000285021.fa.fai000066400000000000000000000000211467060157400215140ustar00rootroot000000000000003 33495 23 60 61 bcftools-1.21/test/csq/ENST00000285021/ENST00000285021.gff000066400000000000000000000125621467060157400211470ustar00rootroot000000000000003 ensembl_havana gene 21 33495 . - . ID=gene:ENSG00000154767;Name=XPC;biotype=protein_coding;description=XPC complex subunit%2C DNA damage recognition and repair factor [Source:HGNC Symbol%3BAcc:HGNC:12816];gene_id=ENSG00000154767;logic_name=ensembl_havana_gene_homo_sapiens;version=15 3 ensembl_havana mRNA 21 33475 . - . ID=transcript:ENST00000285021;Parent=gene:ENSG00000154767;Name=XPC-201;biotype=protein_coding;ccdsid=CCDS46763.1;tag=basic;transcript_id=ENST00000285021;transcript_support_level=1 (assigned to previous version 11);version=12 3 ensembl_havana exon 21 1033 . - . Parent=transcript:ENST00000285021;Name=ENSE00001914924;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001914924;rank=16;version=2 3 ensembl_havana CDS 815 1033 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 2164 2253 . - . Parent=transcript:ENST00000285021;Name=ENSE00003687231;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003687231;rank=15;version=1 3 ensembl_havana CDS 2164 2253 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 2782 2875 . - . Parent=transcript:ENST00000285021;Name=ENSE00003545725;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003545725;rank=14;version=1 3 ensembl_havana CDS 2782 2875 . - 1 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 3436 3605 . - . Parent=transcript:ENST00000285021;Name=ENSE00003595332;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003595332;rank=13;version=1 3 ensembl_havana CDS 3436 3605 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 3688 3822 . - . Parent=transcript:ENST00000285021;Name=ENSE00003617482;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003617482;rank=12;version=1 3 ensembl_havana CDS 3688 3822 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 7209 7290 . - . Parent=transcript:ENST00000285021;Name=ENSE00003582711;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003582711;rank=11;version=1 3 ensembl_havana CDS 7209 7290 . - 1 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 11209 11369 . - . Parent=transcript:ENST00000285021;Name=ENSE00003552241;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003552241;rank=10;version=1 3 ensembl_havana CDS 11209 11369 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 12885 13766 . - . Parent=transcript:ENST00000285021;Name=ENSE00003584932;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003584932;rank=9;version=1 3 ensembl_havana CDS 12885 13766 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 14615 14704 . - . Parent=transcript:ENST00000285021;Name=ENSE00003633829;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003633829;rank=8;version=1 3 ensembl_havana CDS 14615 14704 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 19687 19807 . - . Parent=transcript:ENST00000285021;Name=ENSE00003609011;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003609011;rank=7;version=1 3 ensembl_havana CDS 19687 19807 . - 1 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 20302 20459 . - . Parent=transcript:ENST00000285021;Name=ENSE00003659363;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003659363;rank=6;version=1 3 ensembl_havana CDS 20302 20459 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 22043 22127 . - . Parent=transcript:ENST00000285021;Name=ENSE00003554298;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003554298;rank=5;version=1 3 ensembl_havana CDS 22043 22127 . - 1 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 23131 23254 . - . Parent=transcript:ENST00000285021;Name=ENSE00003656671;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003656671;rank=4;version=1 3 ensembl_havana CDS 23131 23254 . - 2 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 25312 25424 . - . Parent=transcript:ENST00000285021;Name=ENSE00001160407;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001160407;rank=3;version=1 3 ensembl_havana CDS 25312 25424 . - 1 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 27741 27936 . - . Parent=transcript:ENST00000285021;Name=ENSE00001160413;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001160413;rank=2;version=1 3 ensembl_havana CDS 27741 27936 . - 2 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana CDS 33340 33442 . - 0 ID=CDS:ENSP00000285021;Parent=transcript:ENST00000285021;protein_id=ENSP00000285021 3 ensembl_havana exon 33340 33475 . - . Parent=transcript:ENST00000285021;Name=ENSE00002078782;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002078782;rank=1;version=2 bcftools-1.21/test/csq/ENST00000285021/stop-gained-inframe-indel.txt000066400000000000000000000003331467060157400243240ustar00rootroot0000000000000013461 CTCTTTA C stop_gained&inframe_deletion|XPC|ENST00000285021|protein_coding|-|430YKE>430*|13461CTCTTTA>C 13461 CTCTTTA C stop_gained&inframe_deletion|XPC|ENST00000285021|protein_coding|-|430YKE>430*|13461CTCTTTA>C bcftools-1.21/test/csq/ENST00000285021/stop-gained-inframe-indel.vcf000066400000000000000000000007231467060157400242660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 3 13461 . CTCTTTA C . . type=ENST00000285021:14158587-CTCTTTA-C;EXP=stop_gained&inframe_deletion|XPC|ENST00000285021|protein_coding|-|430YKE>430*|13461CTCTTTA>C bcftools-1.21/test/csq/ENST00000294661/000077500000000000000000000000001467060157400166545ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000294661/ENST00000294661.fa000066400000000000000000000232561467060157400210210ustar00rootroot00000000000000>1 1:85715639-85725355 GCAAGAAACAGGTTTAATTGGACTTACAGTTCCACATGGCTGAGGAAGCCTCACAATCAT GGCAGAAGGCAAGAGGAGCAAGACACATCTTATGTGGAGGGCAGCAGGCAGAGAGCTTGT GCAGGGCAACTCCCTGCACTGATGGTTTTTAAAACCATCAGATCTCGTAAGACTCATTCA CTATCATAAGAACAGCACCGGAAAGACCCACCCCCATAATTCAGTCACCACCCATGACAC GTGGGAATTGTGGGAATTACAATTCAAGTGAGATTTGGTTGGGGACACAGCCAAACCAGA TCAGGATCTCAACATGTTGCCCAGGCTTAACTTAAAGTGCAGGAAACAATCAGAAGTATC AAGTGACTCGATTCTCTAAAATGAAAGATACTTGGACAGATGATTTTTCTTATGTATATG GATTTTTAAGACTTTTCCCCACTAGGTTTCCACTAGCTCAACCAAACTTCACCTCAGTAC CCACATGGACACTTGTGCAAACACGTTCCCAGGACATCTCTAAAGGGGAAAATAATCTAT TCTCTAATGTGATGATGAATGTAGAGTGATATGACAGTCCGTTTTCCAACCAGGAGATAC AAATGGCTGAGTCAGACTTGCTCCAAAATATTTAGCCTCTTCCCTAAGTCCTGTCTTCCT CCTCATACAACATACTCTGCACATCTCCCAGGAAAGAGAGAAAAAAGTTTGCTTTCATGC TAACTTAAGAACCTTGCAATATTTCAGTAACTTCTGAGATATTTGCTCCACCAACACATG CATCCAAATTTTAGATTTCTCCAGAGCTTGGGAATCACAACTTCACAAATATAACTTGAT TTGGTTGTGTTTGGTGTCATGTACATACTATGGTCTTGCTTTGTCACTTGATGCCACTCC TTAGTATATGATACCACAGATTTCCAAATTCATTACAAAGACTACAATCTTAAAAAAACA TATTCTTGCTTTAGCAATTACTTCAATTTTGGGATTCATATATTTGCAAACCTGGAGGAT GGGCAGCTATAGAATTGGTTTTTCTAAACTCGATGATATACTGGAAGCCATCATGCTGTT ATGGACCTTCATTCCACAAAGCACCATGGCTGATGCAATCACTCTTAATGACTTTTATGA ATTTTAATCTACTTGATACACATGCCTAGGTAAACAAATCTCGCGTAATTGTTCAAATTT TATCTTCCACAATGGGGAAAAACAGATTTAAAAAAAAATACTTAGATTATGTCTTTTTCT TTCTAAATTATTTTTTGTAAAGATGAGGTCTTATCATGTTGTCTAGGCTGGTCTCCAACT CTTGGCCTCAAGCTATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAAGCATAAG CCACCATGCTTGGCTGTCTTGTTCTTATACACTGAATGTGCACTGTTCTGTAATTCTTAT CTCTTAAGGGCTTCAGATTCATGGAAAGATTGATGCAGAGTGTAACCTTTTTATTGTTCA AAATGCTACAAATAACTGCATTTTGGAACTCAACGATCACACCTTCCCAACTACTTCTTG TTCATTTTATTATTACTATACGCAAAGCATTAAAATAGAAGCTGGGTAGAGAAAACATGT AGAAGTAGGGTTACCAGATAAAAGATGTTCAGTTAAATTTGAATTTCAGATAAACACATT TTTTGTATATGTCCTGAATATTAAATATACTAAAACATTATTTATCTGAAATTCAAATTT AACTGAATGTCCTGTAAACTTACAATTTAATAAAGAAATTAATGAATAACCATAAAGCAC AGATGACAAGTACAGTCATCCAATCAGGAGAGGAAAAGATCTCTACTAACGGATCTCCAG GTACAACAGAAAAAAGTACCTGGAAGAGATGACAATTGATGTCATTCCTGAAAGATGACT AAATTTTGACTGGTGGACAGGTGGTTTAATGTGATGATTTTGAGGTTCAAGTGTCCCAAG TTAAATTCCAAATGAACCACTCACTAGCTGTGTAACATCAGACAAGCTACTCAAGCACTC TTTATTATAAAATGAGAATACTAATAATACCTTGCGCTAGGTTGTTTAAGGATCAGAGAA AATATATGCACAAAGCACCTGGAACACAGGAGGCACTCTTTAAATGGTAATACTTCTTAT TACAACTTAAAATGTCACACGACAAATAGGGTACTTGTCACAGACAAACATTCAAATGTT AATGTTATACAGTAATAGTAATATTGAATAAGTAATTTTATTTCCATGATCTATTTACAC TGTACAAAGACTGTTGAAAAGCACCCTACAAGTTCACAGTACATTACAATATATTTACTT TAAAAATATATTCCTTTATAAAAGGTTTATAAGAACATTGGCATGTCAACATGTGACAAA ACTCTCAAAGCATGTCACCAATTCTGTGAGAGCAAGAATGCATCCAAGTGTTATCAATTT CACAATCACAAGTCACCAGTTGAGTTTTAAATACATACATGTTTTAAATAAAAAAAGAAT TCTATAGTGGAAAGTTCTTGAGGCAATACTTATTAGTTCATTAACGTATGCATTTTCATG GAGATGTGGCATAATAACCCACAATATCAACTTAATCTGTCCAAAGAAACATTTCAACAA GTTTAGCAGTACAGAAATTCTGGTCATTTGTTTCTACTTTTTCTTCTTTGCTGGTTCTCC TGGCTCTACTTTGCGCTTTTTAGAAGTATGCTCATCTTTTTCATCATCTTTAAATAGAAA AGGAAGAGTTTCAATCAGTAATTTTAAAAAACCCAACATGTTAAGCATTAAAATTTCACT GGCTTTATACCAAAATTATTACCCTCATCAATTAATGTTTCTCTCAGAGTTTCCCAATAA AAAACAAGAATTAACTTTTAGAGCTCTGATTTTTAAATGCAAGTGAAAGTGAGCAATTTT TTTTTTCAATTGCAGCCATACAAAATTCACAAAGTAACTCTTTAGGTGCTATACTAAGGT AGCTTAAAATAAGTGACTTTACTTCCCCCAAATCAGACTTTTGAAAAAGGCTCCCAAATA CTCAGCAAGCTTGTCCAACCTGCCTTATTTGTTGTTGTTGTTCTGTTTTGTTTTAGGCTT TTAGCAGCCTGAAGCCATGGTTTTTAGTTTCTGTCTCTAGTGATAAGCAGAAAAGAAGGA TGATGAAGGGGCTTTATTGGCCCAACCAATAACAGAAACTAAGAACTCATGACTGTATTC TCTCCCTTGGACACCACTGCATGATAGTATTTACATTGTATATATTAAAATACAATCAAT GCTTTGTAAGAATGGAGCATATTGTTTTCTTTTTACAAAAAATAGGTATCACTCTAACGA TGACATTATTTAAGTGGCTATCAGCTGTCCTTTTCCTTTCAATCTGCTTTCTCTCCTCCA AAAACAACTTCTTCTGCCCCATCACCTTCTCCACCCACCCCAAATCCTTATTTTGAGGTT AAAAAGCACTCACAAGTAGGTTTCCCCAAACCTCTATTTGGAATTTTATTCTAGTAAGTT CTAATTCCCATCCCCGCCCTCCCCATCCCCACTCCCACGATGGCCAGAACATTTTAATGG CAACAGAAAAATACATATCTTCCTACTTCATATTATGGAGAATTTGGAGAGGGGAGGGAG GTTAGAGAAGAGCCTTACATTAAAACAATGTTCTTTACACCTTTCCAAAATGTTAATAGT ATCTGTAGCCACAGAAAATTTCCAATTCATAAAAATGTTGTCAAACCTGGAAAAGTGAAC TCTTTTATTGTATTTTAAAAAATCCAACTACATGGTTAAAAAAAAAATACAGGGTAGCAC AGACTAGTTGCTAATTCCATCTCCCTAAGCAAATGTGTGGTATTAAGAACTCCATATAGA CAGAGTAACATGGAAAAGATGTTATGATTTATAAAATACAAATTTATTTTGAGCACATTA CTAATTAATTGTAGCTTTTGACTTTATTTTCTTGATCAACAGATACTCAAAAAGTTCAAC AGGTTATCATGTGGAGATCTATAAAATATCTTGATATTGAAAGGAGCCTTCATTATTAAA AAATGTGAGGAACTACTGACATCAAATCATAAATTCCTTGAAGGAAATATTAAAATCTTA AGCCTTCAATTCCCTTCTGCTGACTGTACCATAATCAGAATATCTCATTTATTGATGCAG ATAACAATCAATACCATTCATCTTCACTCCCCTTCAAGCACAGCACGGTGATGTTATTCA TATGCTTCACAGAGCACTATGGATTTATGTAGGCAGTGGAATAAAATACAATTCAGATCA ACTCACCCCAGGAATTTACAAATCAAAGTTTTAATCAGTAGTTCATCATGTTCATACAAA AACACTGGCTCCACAAACCAAATAACATGGTATACCACCAAAACAAGCCAAACGTTTTGC TTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGATGGAGTGCAGTGGCACC ATCTCAGCTCATTGTAATCTCCACCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCC CAAGCAGCTGGGACTACAGGTGCCTGCCATCACACCCAGCTAATTTTTTGTATTTTTAGT AGAGACGGGGTTTCACGGTGTTAACCAGGATGGTCTCTATCTCCTGACCTCGTGATCCAC CCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCACCTTT TGCTTTTTAACGAGTTAATTATCACTAAGCTCCTCTTTTGAGATTTTCAGTAGTGATAAT ATAAAAATGGAAAGTACTAAGTTTACTATAATATTCACTATGCATTAGCATACATTTAGA TGATACTGAGATATTTTTGCTTTTAATTTGCCACTTATTACAAGTAAATTAACTGAATAA CAAAACCACAAACTACTGAAGTTAAAAAGTAACTGGCTATCAGTGATTTGAGCAGAAGTG CTATGCCATCTAGTGTCATGACAAGGCATTGCTTTATAAACTAGAGTAGGAAAAAATCTG AGCAATGTTCATTTATCAATTTTACTGAGCTTTTTTACTCGGTCTCATATAGTATAGATG TACTGGTAAGGAAACAATTTTTTTATTATGGAACTCAAATCACTCAAGTAAGTTTAACTT ATCAATAGACAAACTTTCTAAATTCTAAAAAGTGTAAACTAAAAATCACTATATTAATTA TGCTTTTACAATTAATTATTATACATGTCAATAAAGCTACAACTAATAACTAAGCTTTGC TTACCTACATTTTACAACCACTAAAACCAGAAGTGGCAGGGTGCGGTGGCTCACACCTGT AATCCCAGCACTTTGGGAGGCTGAAGCGGGCGGATCACGAGGTCAGGAGATCGAGACCAC CCTGGCCAACATGCTGAAACCCCATCTCCACTAAAAATACAAAAATTAGCTGGGCGTGGT GGCGTGTGCCTGTAGTCCCAGCTACTTGGCAGGCTGAGGCAGGAGAATCGCTTGAACCCG GGAGGCGGAGGTTGCAGTGAGCCGAGATCACACCACTGCACTCCAGCCTGGGCGACAGAG CGAGACTCCATCTCAAAAAAAAAAAAAAACCCGAAGGGCTGATAAGCAGCAAGACCCAAT GATGAGTTCTGAACCTTTCCCAGCCCTTCCTCTAAAGTAACTGGAAGACGTTAACCGGCA ATAAAAGGCCAAAGGGCAGAATGGGGAAGCAAAATAAAAAAGTCACTTGCTAATCTAAAA TCTGGGTAAGAGTGTAGAGTTTCTGATATATATTTTATGAATGAAAAAGAAAGGCTAAAA AATTATGACATAATTGATTTTATAGGAATCTGAAAATCACTTCTAAAAAATGGGTCTGTT ATTTGATTTTGCCTGTATTTGTTTTCCAATAAAGGACCATCATGTGATCAAAAAGACAGA AATTATCTATGTGAATAGCAGTGTTACCTGCCACATATTTGGAACTCCTTCTAACTTAAC TCAAAAGCTAAGCTAGAAAAAGATAATTCTTTCTTGCTTGCTTGCCCTGGTGTATAATCC TGGTTTTTTCCATATAACTACAAAGATGTGAGAGCACCAGCCTATGGAAATCTAGTTTGA GTATCAACCCTAGTATCTTTACTGCCATTCGCCCTACAGAAGAATAGCTATATCTCACTG TTGAGAAATGGCTATTCATCAGGAGACCAAATCCCAGTTTAATAAGGCATAATTTCTATT TAAAGGTCTGGATTTGAATGCCTACTACTCTGTCTCTTCTTTAGCTGCGTGAATGAATTT GGGTAAAGTCCCTAATCTCAGATTGTTTTATCATCTGTAAAACAGTAATAATGAGTCATG TAGCACTTCTGTATCAGGTTGCTCGGAGTAATAAATTAGAAAACTGTGTGAAAGTGCCTA TTTTAGAATTTGGCATTTTCTAGTTTGTGACCTTGGACAAGTTATGTAAGCTATCATTTC CACATTTCTCTATCTTATTTCACAAGGTGTTGTAATAAAGATTATTTAAGCAAATATATT TTTACTAATTATGAAAAGGAATGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACT TTGGGAGGCCAAGGCGGGCAGATCACGAGGTCAGGAGATCCAGACCATCCTGGCTAACAC GGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGTGTGATGGCAGGCACCT GCAGTCCCAGCTGCTTGGGAGGCTGAGGCGGGAGAATGGCGTGAACCCGGGAGGCGGAGC TTGCAGTGAGCCGAGATGGCGCCACTGCACTCCAGCCTGGGCGACTGACCGAGACTCCGC CTCAAAAAAAAAAAAAAAAAAAAGAAAAGAAAACAAAAAGATTGTACAATATGAGATATT ATAAATGTTTACATCATTTAAGGTCTGCAAAAAGATGCTACTTACTGAAGATGCTCCTTC ATTAGTGACTAATACATATTAGAAGTCAGCAAAAGTAATGGAAAAGCTAGGTAGAATCAA AATTAAAGAAAGAACTGCCAATCAGTTCTCCTTTCTCTTAAAACAAAACATCACTCCCTG CATGACTGTTAAAAACGGGCTAAGTAGCCCTTGTATTGTGGGAAGATCAGAAATCTGTTT AACAAAAATGGCATACTTTCTTAAAAATAATGGTCCAAAACATTAGTTCAATTCAACAAT TACTGAATACTTACAATGTACTCGATACAAACACTTCAAATCCTGCTGTTTGAGGAACTC ATCATAAAGCAGACAGACTTTTAAAAAAATCACATACAAGTGATGAGGGCAATCAACAGC ATTAGCATAAACAAGGTACAAAGGAGCAAATAATTATTAGAGGTGATACCTGAGATTTCT TCTTTTGATTTGGATTTTGAAGGATGAATTAGTTTACTAGCCAGAGATAAGAAAGAACAC TAAAGAATAAGGTGCAACGTATACTGAAAGGCAGGGAACCATACAATTCAGTTCTGGATT TCAAGATCTTCAAGTGCTAGAAAGGGGCCATTAAAAATGACTGTGGACAGGGAGAAAGGG CCTATTAATACAAGGCCTTGACTTTATCCCGTTGAAGGGTTTTAAGCAGGCAAGTTATAT AATCAGATACGACTTTTAGAAACTCAACACTAGCTGCAGTGAAGGATGGTACAGATTGGA TAAGAATGTGTAGGCAAAGATTACTGTGACAGTCCAAGTAAGAGACGAAATTATGCTATT ATGAACTAAAGTAAAACAACTCAGTCATTATCTTCCTATTACTATGTAGTAATGCTCAGT TAAATTCATTTTGTCATACTAATTTTAGCTCTGAAGCACAACTGCTTTAATAGAAAATGA AGCCTTCGGCCGGGAGCGGTGGCTCACGCCTGTAAATCCCAACACTTTGGGAGGCCGAGG CAGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACCCCA CCTCTACAAAAACAAAAAAAACAAAAAAAACAAAACTAGCCCGGCGTGGTGGCAGGCGCC TGTAATCCCAGCTACTTGGAGGCTGAGGCAGGATAATCGCTTGAACCTGGGAGGTGGAGG TTCGCAGTGAGCTGAGATGGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAATGCT GTCTCAAAAAAAAAGAAAAAAAAAAAGAAAAAGAAGAAAAAAAAGAAAATTAAGCCTTCA GTACTTTGTAGCTACAGTCACAAGAAACCATGAATTGATTTGTGTTGTTCTAATAATGCA TCATAAATCTGACCACTGGATGAGATATCAGATATTTTACTTTAAAGCCTGAATAATTTA TGATCTTTCACTAAAATACAGCAACTACTACTAGCTGAGCTATCAGAGACTTCATGTTAA AGCCAAATATGTATGATCTTTCTCAAAAGCAGAGCAGTAAGTATCCAAAGACCATCAAAT TAGTTTGTCAATTCGCTAGATTTAATTTTCATTCATTAAATATCTCATTCTTTTTAAGCC CATCACGGGGATCAAAATAGACCACCATCGGATTCTGACTTTCCTTACCTGATTCCAACG TCTCCTCCCCTTCTGGTAGAAGCCTAGCTTTCTTAGCATTCTGTGGAGCATCATCACCAT TGTCCTCATATATGTTAGACCATTTTATTGCCATGTCAAGCTCTGGAGGCGGAGGCTTCT TCTCAGTGGTGTAGGTCTCAGGAGGTGGTACATAATTTGACTTCCATATTTTGAATTCCT TTGGAGGCTGTTAAGCAAGCACATTAAGAAGCACTGTGACGAACCGAGGTTCCTACGATG GACGTGGGCACATGCAACTCCCTGCCGTTCGCTTATCGTTCAGGCTGACTTTTTTTTTCT TTAAGGTTGAAAGACACATTTTTCCATCAAAATCACAATACTGTTAAGTGAAAAGCCAAA GGGTTCCCTATATGAATAAAGCTAATAACTTTTAGTTACCAAAGAAGAATCCAGTCTCAG AGATACTACGCCAAGGCTGACCCCTTCAGGAGGCTGCAGCAGACACTGTCTTGGAGGCAG CACCGCAGGCACTTCGGCGTCAAAGGGAAGGGGTCTCAGGGAGAAGCTGCAGCGGGGGGG GCGGGGGAGTCACCACTGTTAGTCCTCGCCGCGCGGGGTCGGGGCACCGAGCGCGGAGGT TTGGGTCTCCTCACAAGGGGCGGGGCTGCGGGTCCGGTCTAACACCCACCAGGCGGGGAG AGGGGGCCAGGTTTCCCAGGGCTTGAGGTGGGAGGGGGTGGTGCGGCATCCCGCGGGGGT GACTGCGTGTGGGGGGATGGACAGCAGGTCCCCAGCAGGGGGCTCAGGAGAAAGGGGGCG CAGGCCGGGGCCGAGACCGAGAAACGGGGTCGGGGACCTCACCTCCTCAGGCGCCTTGAC GACGTGCCTCTCCCAGTCTATCTGTTTGTTGAGCGGATTGTAGAGAAAGGCCGGGCGAGT CACGCTCCTAAACAGCTCGTCAGGTCCCGGGAGCCGCTTCTCCGCCTTGTTCCTACAGCC GCCCGCCGACTTCGCCGGATCCGGGGTTCTGCGACTCGTCTCCTCCGGCTCGATGTTATC CTCCTCGTCCGAGGAGCCTGAGCTGCTGCTCCCGTATGCCGCAAAATAGCTCAGAGGGTC CTTCTCCTCCGCTGCCATGACGGCTGCGAGCGACAACCCAGCACTCCGCCGGAAGCC bcftools-1.21/test/csq/ENST00000294661/ENST00000294661.fa.fai000066400000000000000000000000201467060157400215370ustar00rootroot000000000000001 9717 23 60 61 bcftools-1.21/test/csq/ENST00000294661/ENST00000294661.gff000066400000000000000000000023221467060157400211640ustar00rootroot000000000000001 ensembl_havana gene 1 9717 . - . ID=gene:ENSG00000162642;Name=C1orf52;biotype=protein_coding;description=chromosome 1 open reading frame 52 [Source:HGNC Symbol%3BAcc:24871];gene_id=ENSG00000162642;logic_name=ensembl_havana_gene;version=9 1 ensembl_havana processed_transcript 1 9717 . - . ID=transcript:ENST00000294661;Parent=gene:ENSG00000162642;Name=C1orf52-003;biotype=processed_transcript;havana_transcript=OTTHUMT00000027614;havana_version=2;transcript_id=ENST00000294661;version=4 1 ensembl_havana exon 1 2747 . - . Parent=transcript:ENST00000294661;Name=ENSE00001388570;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001388570;rank=4;version=2 1 ensembl_havana exon 8569 8767 . - . Parent=transcript:ENST00000294661;Name=ENSE00003676223;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003676223;rank=3;version=1 1 ensembl_havana exon 8980 9106 . - . Parent=transcript:ENST00000294661;Name=ENSE00001870157;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001870157;rank=2;version=1 1 ensembl_havana exon 9403 9717 . - . Parent=transcript:ENST00000294661;Name=ENSE00001067212;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001067212;rank=1;version=4 bcftools-1.21/test/csq/ENST00000294661/non-coding-boundary.txt000066400000000000000000000001631467060157400232710ustar00rootroot000000000000009715 GCCGGAAA G non_coding|C1orf52||processed_transcript 9715 GCCGGAAA G non_coding|C1orf52||processed_transcript bcftools-1.21/test/csq/ENST00000294661/non-coding-boundary.txt-l000066400000000000000000000001631467060157400235220ustar00rootroot000000000000009715 GCCGGAAA G non_coding|C1orf52||processed_transcript 9715 GCCGGAAA G non_coding|C1orf52||processed_transcript bcftools-1.21/test/csq/ENST00000294661/non-coding-boundary.vcf000066400000000000000000000005511467060157400232310ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 9715 . GCCGGAAA G . . EXP=non_coding|C1orf52||processed_transcript;type=ENST00000294661:85725353-GCCGGAAA-G non-coding exon boundary overlap bcftools-1.21/test/csq/ENST00000295641/000077500000000000000000000000001467060157400166535ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000295641/ENST00000295641.fa000066400000000000000000000450301467060157400210110ustar00rootroot00000000000000>2 2:220462562-220481193 TTTTCTTCCGGGGCGGGACTTCCTTTCCATCATTGATAGGCGCCGGGCAGCTGAGCTGGT AGGAGGACCAGACGGGGAGGTTCGGTATGTCTGACCAGGACTTATGTTCCTCGAAAGGGC GGCCAGGAGGATGCTCTTCCTCTCTTTTCTTTCTCGCCTTTTTCTCCGCATGACGCCTCG GTTTGCGCGGACGCCCTGGGCTTTTGGCACTACCGCCCACCTGAGGCTCTTCCGCTTCCT CTTTCCCCCCCCAGGCTCCGCCCCCCAGCGTCCCGTGGCCATGACGACCGCTCAGAGGGA CTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGTGAGTGGACTTCCGGTTG GGCTGGGCCTCGGACCTCGGACGAGGTGGGGGTGGTGCTTTCTGGAGACACGCCCTGAGA GTCATGGAGTTACGACTGGTAGGGTCACCAGGTGTCAGAGTTCAATTTCTTTACTTTTCC CAGGTTTGTTCGCCCTTACAGTGTCCTTTGCCTGTGATAGCCTAAACTCTAGCCGTCCTT TGAGGCCAAAGGGCGGTATCCCTCCCTCCGTGCCTTCTCTGACACTGTCAGAAGGAAGTG ATCATTACCTGACTAAAAGCCCCTCAGGACCAGGGACTGATCTCGGTCATAATCATTATT GTGTAGCAAGGTACTAAATACAGTAGATAGAAGCACGAGATTTGGAGTCGGACCCACTTG GGTTGGAATATCAACCCTCTTTCAAACTTGCCATACTGTTTCCTGAGGCTCAGTTTTCCT CACAGATTGGCATAGTGATTGTACTTAACATTTGTGGGGATTCGTTTTAATTCATGTATT TAGTACAATGCCTGCAAGTATAGTAACTGCTTACAGTTGGGAGCTATTGTTATTGTAATG ATTTCCCTGATGCTTGGCACTGTGCCTGGGCATAATGGAGCCACAGTAGTTGTTGAATAC TTGGTTGGCATTAGTTGTGGTAGAAAAAGCCTTGGCTTTGAGATCAGATAGGAGAAGTAA CTTCCTACCAATTATATGATCTCCATCAAGATTTTTCACTTTTTTGAACCTCAATTTTCA TATCTGTAAGATGGGGTTAATAGTGCTTCTCTTTGAGAGATTCTGAGAAGGTTTGAATGA GATACCAAAGTCATCTGGTACATACTACAGTTAATGTTAGCTGTCCTCCATCACTCCATG CTCCTATTGACGATATCTGTGGAAGCTCTCTTTATAGCAGTTTTCTTTTCTTTCTTTTCT TTTTTTTGAGACAGAGTCTTGCTGTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCAG CTCACTGCAACCTCCACCTCCTGGGACGAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAG CTGGGACTACAGGTGTGCACCACCATGACCGGCTAATTTTTGTATTTTTAGTAGAGACGG GGTTTCACCATGTTGGCCAGGTTGGTCTTGAACTCCTGACCTCAAGTGATTAACCTGCCT TGGCCTCCCAAAGTGCTAGGATTAAAGTCGTGAGCCACAGCACCTGGCCAGTAGCAGTTT CATTTCCTGGCTTGTATTGATAACTTTGCAAATGTCTTATATCCTTCTCTGGGAGGAGAC AACTAGGAGGCCCTTTGAACGTGGGAAGAGTCCTTGAACCATGTCTGTATCTATCCTCAG TGTCTAGTACATACAGAATCCTTCATGTCAGGTTGTAGGACTTGTTAATTTATTCAGTGA TGAATGGTGGGTGTGTGAATGTGTGACTACAAGGAGGTAGCAGGAGAAGAGCTTTGTGGC AGCAGAATAGTTTTGTATCTTGATTGCGTGGCTGCAGGAATTTATATAAACAGCATATAG CTATATATACATATTGTACCAACATCAGTGTCCTGAATTTTTTTTTTTTTTTGAGATGGA GTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTATGATCTCGGCTCACTGCAACCCCT GCCTCCCTCCCAGGTTGAAGTGATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGACTACA GGCATGCACCACCATGCCCTACTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCAT ATTGGCCAGGCTGGTCTTTAACTCCGGACCTCGTGATCCACCCGCCTTGGCCTCCCAAAG TGCTGGGATTACAGGCGTGAGCCACCACGCCTGCCCTTTGTGTTTTTTTTTTTGTTTTTG TTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTACCTCTGTCACCCAGGCTGGAGTGCAA TGGCTCAATTTCGGCTCACTGCAACCTCTGCCTCCTGGCTTCCAGCTGTTCTCTGGCCTC AGCCCCTCGAGTAGCTGGGATTACAGGCGCATGTCGCAATGCCCAGCTGAGAATATTTGT ATTTTTAGTAGAGACGAGGTTAGAGTCGTAGAATAATTTTTTGTGTTTTTAGTGGAGACG GGGTTTCACCATGTTGGCCAGGTTGGTCCTGAACTCCTGACCTCAAGTGCCTTGCTCCCA AAGTGCTGGGATTACAGGCCTGAGCCACGGCAACCAGCTCAGTGTCCTGACTTTGATATT GTACTATAGCTATATAAAATGTAACCATTAGGGAAAACTGGGTAAAGGATACAGGGGACC TTTCTGTATTATTTCTGCAGCATTCTTTGACTCCATACTTATTATATTTTTTAAGCCAAA AAAGCATTCCTTCATGCCTAGCTTGTAGCTGCACTTTTTTAGGTGCAGTGATGAATACCA GAGTGATCAAAAGATGCCCTCAAGGATGAAAGTCTCATTAGAGAGAGCAGTTTTAACAGA CAGCAATAACAATGCCTTAGTGCTATAATGAATAGTTATTCTATGACATACTTTTTAGTA TTGTTTGAAAGTTTCTACAGATGTGCTTTGCAATCAGAAAAAGAAAGAAAGATAAAACTT CCAATTAACTTTTGTGTAATAATGAGTGACTGCAATATGAAAATTCAGCAGTATTACTTC TTGAGGCGGCTTCCTGGAGGAGGCTGGTCTCAAGCTGGGCGGTGGAAGGGGGTGTCTCAT AACAAGAGAGAACTGTGAACCAAGCTGGCTGTATTTCCAGCACTGTCAGTAGATGAGGCT CTTTTGAGCAGAAGGTGAAAGAAAATTTGGAAGAGTTGGTTGGAGTTGTGTAGCCAAGCA GTCTCATCAGGCTGAATGAAATGTTAGGACTTTTTTTGAAGATGAGGGGAGCCATTGAAT GCTTTTGAGCTGAGAAGGAGATAGAAAATTTGATCCTGCAATAGAAGATCTACAATATGG ATTGGAGTGGGTATATTTTGGCATCATAGAGCCTTAGAATAAAGAGAAAAATCTTTTCAC TGTGTCTTCCCTCCTGTTTGCCCCTTTTTCTGCAGGGGATGTGGTCCTGTCTGGCTGTAG CACCCTGAGCCTGCTGACTCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCT GGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTGGCTCTGCCCTCCCATCCTGCCGACTC CCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAA GGTTCTGGGTGTGGGGAAGAGGCAGGATGTGCAAGGAGCCCAAGAGAATGATGGAAGTTG GGGATAGGGTAGGGGTGCAGAAGTCTGCAGTGCCAGGATCCAGAGGGTGTCAGAGGTACC AGTGGTTGTGCTAAGGAAGGAATGTTGAGGGCAGGAAGATCTGCTGTGCCTCAGTAAATT GAGTTTTTTTTTTTTTTTCAGCTGGTCCATGTTGCTGGTCCTGGCCCCACAGGGCCCATC AAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGGTATGGGGACACGGGGGGATGTTG GTGCACAGCACCCAACTTGAGGCAGCCCCTTGGGGATGGGAAAGAGAAGAGCCTCTTTGG TGAGGAGGCCAGGCCTGAGTATACCCATTGCTCTGCAGTCATGTGATATCCACTGTCTTT CCATTTACTGCTTCCCTAAATCATAGCTGGGCTTTGTGGTCTTCTCCCTCCTCCCAACTA GGGGATGGGGATGAGGTCTTTGTCTTCTGTGGGGTTCTGCCTTCCTCCCTCCTCTTTCCT TGTCCCAGCTCCGAGGTGTTCCCCTCCACTGTCTGCATGGCCTCCGAGGCATCTACTCCC AGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGTAAGGAGAGTGAGGG GTGAGCTCAGACACCTCAACTTGAGAGATGTAGAAGACCAAGCTCTGATGTTCTCCCCTC TCTGCAGCTCTCCCTGCCTCCTGCTTCCCTCTAGACAGTGTCCTCACTCCCTCTCTGTGT TCCCGCAGCACTCTGTAACTGCCTGTATATTTATAGTCGTACCTACCATATTATATTACA TATTCTAGTGTCTACCTTCCCACTGTCCCTACAGTGAGTTCTTGGGTCAGGGACCTGGGC TTTAAGCCTGTATCTTCAGATGGAGTTCAGTGTATAAAAAATGAATGAGTGACTGGGTGG TAGAGCTTGGCCTTGGCATAGGGAGGAAGGGGAGGGTGGGGTAATGAAGCACCCATCTGT CTGCTCAGGAGCTCCTCTCAGCCTGCGGCGGCGACTTCTGCTCTGCCCTCCCTTGGCTGG CTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGCTCCCTGGTGA GTGCCTCAGAGGGAAGAGGGTTTCGAGGAAGGGCAAGGCCAGGCCTTTGGGGAGGAGGGC CAGCTGGTTGACCAGATAGTATTGTAGTGAACATCGATTCTCTGCCTCCTCCCCGTCTCT CTCAGCGCCTCTTGTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACT GTCAGGGATTCCTGATGGTGAGTATGGGCAGTTTGGCAGCTGGCACACCATGGGTCTTTG ATTGCTCTGCTCTCACTCTCTCTCCTTGACCAGCTTTTACTCCCACCTTGCTCTTGCCAT GAGGGTGGAGCTGCATTCTGGGAGATAGCACTGCTTAGACACTAGCATCAGACAAACCAG AGTTCATATCTCAACTTCTAATACCTGTGCAACTTTGAGCAAGTTAGTTACCTCTTGGTT TCTTTACCTGTAAAGTAGAAATCACAAGAGTACCTGGTTTTTTTTTTTTTTTTTTTTTTT GAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCAGCTCACTG CAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGAT TACAGGCACGTGTCAACACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCA CCATGTTGGTCAGGCTGGTCTTGAACTGCTGACCTCAAGCAATTCACCTGCCTTGGCCTC CCAAAATGCTGGGATTACAGGCATGAGCCACCACGCCCGGCTGAATACCTGCTTTTATAG TATTAAAATGATTGTGAAGAAGTACCCAATGTTGCTTAGTCTAGTGCCTAGCTCAGAAAC TGGTAGCTTTTGTGATTATGATGAAGAACCTTTCTTCTGGGTCCTCCCATCCACCTGTCA GAGATAAAGCCGAACTAGTTAAAGTGGTAAGGACAGATTTTTTTTTTCTTTTTTTTTTTG AGGCAGAGTCTTGCTCTGTCACCCAGGCTAGAGTGCAGTGGTGTGATCTTGGCTCACTGC AAACTCAACCTCCTGGGTTCAAGCAGTTCTCCTGCCTCAGTCTCCCGAGTAGCTGGGATT ACAGGTGCCCGCCACCATGCCCAGCTAATTTTTGTATTTTTTAGTAGAGATGGGGTTTCA CCATCTTAGCCAGGCTGGTCTTGAACTCCTGACCTCATGATCCGCCCACCTCAGCCTCCC AAAATGCTGGGATTACAGGTGTGAGCCACCGTGCCCGACCAAGTAAGGACAGATTTTTTA TCAGTGATAAACTATTGCAGCGGGGAAGAGGGTGCAACCTGAACTGAACGCCACTTCAAT TTGTGCAGAGGTGGCTGGGCATTTTAAAAGGAGAGTGAGGGAATAGGAAGGGGAACTGTG AGGGCTTGAGCAGAGTAAGGGAAGTGGAAATGTACGAAAAGCAGAAGTGGAGGTTGATTC ACATGAAGCCCTTCTGGGTTTGCTAAAAGTTAGGCTCCTACCTTCCCACAGAGACTGGGA GATGGGAGCCCTGTCATCAGGTGTTGGCTAGAACAAATGGGAAATTCTTTTGGCAGCCTT GACTTTTCCCAGGCAGGAGCTTAAGGGGGCTAGAGTCACCATTCTAGGGATGCATCCTTG AGATATTAGAACTTTGCTGTTTTTGTTCAGGTTTTTTACTGTGGGGGTTGGAGGAGTCAA CAAAAATAATTTGTGTTGAATTTTGTTGAACTTGTGCTGAACAAGTCTGCAGTTCTTAAC AGGCCAAAGTTGAGGCCTAGTCAAAAAGAAGGCCCAGAGGAGCCTGAGTAGGGTTTGATC AAGGTGAGAACCTCCTCTAATTCAGGGAAAGAAGAGACACTCCTCTTTCCCCTGAACAAT ATAAATCCTTTTCTTCCTTGATCACCTTTTGTTCACTAAAAACCAACTGAGCCATTTATT GGGACTTGGTAGTGGATGAATTTTGCTGGATGGTGAGAGTGACCAGGCATTTAATGGGGG ACATTTCTATGGAAACAAAAAGGGAAACAAAGATGAATGGTTGGAGCAGACTATAAATCC ATTTTCTGAGTCCAGAGGGCAGCCAGTTGAGATTTCTAGGTGTTGAGCTCTATGTTTCTT TAGATGGTGGAATGAGGATAGCAGTGGCAACCGATGGATTTCTTCGTTTGTAGTTTGAAT GTTTGTGGTGATAGCATAGACAGTGTTGCAGTCACGGTTATTTCCCTGAACAGAGCCTGG AAGATACAGAAGTGTCAGTGGACTTTTTTCCTTTTTTTTTTTTTAATGAGACAGAGTTTC GCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGGCTCACCGTAACCTCTGCCT CCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAAGTGTGTG CCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACAATGTTGGCCA GGTGAGTCTCGAACTCCTGGCCTCAAGTGATCCCCCCTCTTTGGCCTCCCAGAGTGCTGG GATTACAGGCATGAGCCACTGCACCTGGCCGGCTGGGCATTTTAAAAGAGGGCGGCGGGG AGTGGGCAGGGGAATGGTAGGGCCTTGAGCAGAGCTGGGGGAGTGGAAATCAGGTTGGTC CACATGAAACCCATCTGAGTTTGCTAACTAACTGGCACTTACCAAAATAAGGCCCTTACC CTTTCACAGAGACTGGGAGACGGGGCCCTATCTTCAGGAGTTGGCTGAAACAAATGGGAA ATTCTTTTGGCAGCTTTGACTTTTCCCAGGCAGGAATTTAAGGGGCTTGGAGTTGCCATG CTCAGGGTGTGGCCTTGAACTGTTAGGAACAGTGCTGGTGTTGTTCAAGTCTTTTAACGT GGGAGTAGGGGTGGATGAAATCATTTGTGCTGAGTGTGTGCAGTTTTATATAGGCCAAGG TTGAGGCCTAGTCCAGAAGAGGTCTCAGAGGACCCTGGCTAGAGTTTGGTCAACGAGATA ATCTTTTTCTCCCCTGTACCCCTGCCAGGATTTGTGTGAGCTCCACCATCTGGACATCTC CTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCT GATACTGCGAGGCAATGAGCTTCGGAGCCTGCATGGTGAGTGGGGGTGTGTGATGGGGCA AGCATGGAGGGGAAGGGGGAGAGTGAGGCTGGGGCTGGCCTGGGGACCATGTGCCTCTAG AGCCTTGAGAGGGCTTATGGGGAGTGCAGGGGTGCTCTGGCCGGTCTTTCTGCTGCAACC TCCCCCAGTGCATGCACCACACTCACTTGCGTGTACTCATCCACATGCTCTTCCTTCCTT CTTGCGTCCACCCCAGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATAC AACCTGCTGGAAGGACACCGGGAGCTGTCACCACTGTGGCTGCTGGCTGAGCTCCGCAAG GTGAGATGGGAATGCATCAGGGGCCTGGGAACCACCCTTGCACGTACCCCCCCATGCTGG TTTGGTCAGTGCCTTCTTCACACAGGGAGGGCCAGGGCCCCAGGCCCTCCTCATTCTCCC CTTCCTGCCCCTCAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGA GCAGCCACTGCCCAGTACTTGTCACCCCGGGCCAGGGATGCTGCTACTGGCGTGAGTGAT CGTCCTGTGTCCACTCTTCTTCCCCTTTCCTGCCCAGTCCTCCCCCACCTTGCACCCTCT TGCCATCCCTGGGTGAGGGGCCAAGGACCTGGACCCTGCTTACTGTGTTCTTAATACCTG GAGCTCAGCAGGATGGGCCTACCACATACTCCCTCCCCCTTTTTGTCTTTGCTCAGTTCC TTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGGTCGGTGTGGTTGGGGGGCGAG GACTGTTGGGGGAAGACACGAAGGGAGGGCGCTGGGGAGAGAACAGAGGGCTGGCTGGTG ACAGGGTCTTCCTGGTCAGTGGAAAGTAGGGTCCCGCCTTTTGGCTGGCTTGGGCAAGGC AGAGGTGCTCCCAGGCTCCAACCTCTCTCTCCTTCCTGTCGTCACGTGCCAGACTCACAC ATCCTTGGGGCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGA AACCTCAGGTGGCCCTGACCTGAGTGACAGCCTCTCCTCAGGGGGTGTTGTGACCCAGCC CCTGCTTCATAAGGTTAAGGTAAGCAGCGTCCTCCGCTGCCTTGTGCCTGCGGTTGGGTG TCTCTCCGGGGACTCTGGGCTACAGTGGGCAGGGAATGGTAGGAACTGTGCTTGCACGTG GTCAAGGTTTCTTTGATAGGTTGGATGGCCAGCCGTGGATGGCAGGGCTGGAGGCTTGGC TTTCACAGAACTTCTTCCCTCCACCAACCTCAGAGCCGAGTCCGTGTGAGGCGGGCAAGC ATCTCTGAACCCAGTGATACGGACCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGGT AAGTCAGCTTCATCCCACTAACCTCTCTCGTCCCCAGCGAGCTCACTCTAATTTTTAAGT TACAGTGAAGATCTGCTGGAAGAAATGTTATTTTTTGTTGGGGTAGAGTATTATAGAGGG CTTCTTAGTCTTTTTTCTTTTCTTTTAGTTTAGGGAAAGGAGAAGACTGCTTCTGGGAGC ATTTTGAAAACTTTTCGAGGAACATTAATTTTGTGGGGTGTCAAGAGATCATGTAGGCCA GGTGCAGTGGCTTACATCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGCC TGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATAGAGAGATGTCCATTTCTACAAAAA AATTTTTAAATTAGCCTGACGTGGTGGTGTGCGCCTGTAGTCCTAGCTACTTGGGAGGCT GAGGCAGGAGGATCGCCAGAGCCTGATAGTTCAAGGTTGCAGTGAGCTATGATCATGCCA CTGCACTCTAACCTGGTGACAGAGTAAGACCTTATCTCTTAAAAAAAAAAGTAAAAAACC CCAAAACAAAAGAAAGTGTATATGTATATATATAAAATAATAGGATTGTGGCCAGAGAAG TTTGAGAAATGTGAGGTTGAAGAGAAATAGGTGTGTCAGCTGCCGGCCGTCTCGGGCCCT TCAGGATGCTATCATGTATGCTGAGTCTCTGGAAGTAGCATAGGATGCGCAGCTTGGATT GCATGTGACCACAGGGTTCCATAGGACACGCTTTAGTACATGCCGCGGAGGGGACGCCTG TAGCCTCCCTTGCCCGTGTCCCCATACACAGCCCATCGCCCCCTCATCGCTGAGGAGCAC CGTTGAAGGATTTGGGGCCATCTGTGTGGGGCAGGCTTGCTCAGTTCTGGGTTCCCCTCC TGCCTAGGATGGTTCGTGCAGCAGCACCCGGAGCTGGAGCTCATGAGCAGCTTCCGGGAA CGGTTCGGCCGCAACTGGCTGCAGTACAGGAGTCACCTGGAGCCCTCCGGAAACCCTCTG CCGGCCACCCCCACTACTTCTGCACCCAGTGCACCTCCAGCCAGCTCCCAGGGCCCCGAC ACTGCACCCAGACCTTCACCCCCGCAGGAGGAAGCCAGAGGCCCCCAGGAGTCACCACAG AAAATGTCAGAGGAGGTCAGGGCGGAGCCACAGGAGGAGGAAGAGGAGAAGGAGGGGAAG GAGGAGAAGGAGGAGGGGGAGATGGTGGAACAGGGAGAAGAGGAGGCAGGAGAGGAGGAA GAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGTGAGCCCTTTGTGGGCTGGGGCGAGCTG AGGCCAGGGGCCCTTGGGATGTTTGTGAGTGGTGGGGCCTGGCGGGTGGAGGGCCAGTTC GGGGGAGGGCAGAGTGTGGGTACTTTCCCTCCCTGCAGGCCTTTTCTCTTGGTCTCTCCA CAGCGGAACTCTGTCGCCCCTTGTTGGTGTGTCCCCTGGAGGGGCCTGAGGGCGTACGGG GCAGGGAATGCTTTCTCAGGGTCACTTCTGCCCACCTGTTTGAGGTGGAACTCCAAGCAG CTCGCACCTTGGAGCGACTGGAGCTCCAGAGTCTGGAGGCAGCTGAGATAGAGCCGGAGG CCCAGGCCCAGAGGTCGCCCAGGCCCACGGTGAGTGGGGCGTGGCAGGGTCTCTGGAGGA GCCAGTTATGGGAACATGGCTGTTGTGTGCCCTGCACTGGGCTGGGCATTTCTTTCAGTC TCTCCTTGGCACTAGGAGCCGAGGAGGGGAGCCTCAGAGGTTGCAAGCACTCGGGAAGCT GGGCTGAGGAGCAGGGATTCTGTGCTGGAGCTTGGACGTCAGTACAGGCCTTTGACAGGC TTCAGAGGTCCTGCCATCCTCCATGCTCTCAGCATCCCCTCATCCCTCTGATCACCGCCC CTGCTGTTTTTCACCCGGTCCCCCTCTTGCTGCGCAGGGCTCAGATCTGCTCCCTGGAGC CCCCATCCTCAGTCTGCGCTTCTCCTACATCTGCCCTGACCGGCAGTTGCGTCGCTATTT GGTGCTGGAGCCTGATGCCCACGCAGCTGTCCAGGTGATGGCGCCCAGAGTGGGGGCCCA GGAGGCTGTGGGGATTAAGAGAGCCAGAGGGAAGTGGCAGCAGGCCTGAGGGCCGGGGGC CTGTGGGAGGTGTCCGTCTGGGGTCCGCCTGCTCACAGCTGCCTCTGATCCACCCTCTGT CAGGAGCTGCTTGCCGTGTTGACCCCAGTCACCAATGTGGCTCGGGAACAGCTTGGGGAG GCCAGGGACCTCCTGCTGGGTAGATTCCAGTGTCTACGCTGTGGCCATGAGTTCAAGCCA GAGGAGCCCAGGATGGGATTAGACAGTGAGGAAGGCTGGAGGCCTCTGTTCCAAAAGACA GGTACAAGTCCTGCCCTTGACCTCTCTGCCCACACGCCTCCCCTGTTCCAGGGAAAGTGG CTCTGTGTAGGGGAGTGTGAAGGGGGAGCCCTAGGGAGAAGGGGCTAGAGTGGAGAGCAG TTGTTCTGCCTGGAGGAAAAAGAAAACCGTCTGCCTGCTGCATTTACAAAAAGGAAAACA GAAAAAAAGAAGAAACTATATCCTGTTTTTTTTTTTTTTTTAACTCTAAAAGTCAGGAAA TGCAATCTCTGTAACTGTGCTTAAACATACTCATTATTTTTTCATAACTTGAAGGCTTGT TGTGTTGGGGATTTTTTGGCTGATATTTCAGACACTACATAAAACCTAATGAGCCCTCAC TGCAGTATTGGATTGTGGTGCTGCCTCTGCCAGCAAGTGTAGCTGTTGAGTGAGATGCTT GGGGAGTTGGCTTGGTTTATCCTTCCCGGCTGACCTTGGAAGGTACATAATGTCCTGTGG CATTTCTTCATGCGCTAGTCCTTAAAACAAGAATTGTTTCCATTGTAGACCAGTCAGCAC TATCTTTGAAGAAGACATTGAAGAAGAAATAAATATTCTTGATAACAGCTCTGTGGAAAT GCCAGAATTTTATTAGACGGTTTTCTCTTCTTGGCGGCAGCTGGAGCAGGGGTTTAGATT TTATTCAGAAAATGGAGCCCTGCTCCATTCCCCACTGTGAACTGGCCTGGGCATGCAGCC TTAGTGACACAGCGCAAACAGAAACAGCCCCCAGCCCCTCCCGGACCCTGGCTGTACACC ATGAGGTGCTGTGGTCTCTGGAGCCTCTTCCATGGTGGCGTTATTAATGAACATTACTGT GGGCTCTGTTCTCCTTTAATTTTTTTTTTTCTTTTTTTTTTGAGACGGAGTCTCGCTCTG TTGCCCAGGCTGGAGTGCAGTGGCACAACCTTGGCTCACTGCAAGCTCTGCCTTCCGGGT TCACGCCATTCTCCTGCCTCAGCCTCGCAAGTAGCTGGGACTACAGGCGCCCACCACCAC ACCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGG TCTGTCTCCTGACCTCGGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCG TGAGCCACCACGCCCGGCCAACCATTCTCCTTTCACTTGCACCTCAGTTACCTCCTCTGA ACAAAGAAGGGAATGAACTCACCCCATGGTGCTGTTACGCTATTTAAATGTGACAGTAAG GCACCAAGCAGAGGGCCTGGCACAACACAAAGGTCTCCTGTAAATGGTAGCTGCTGCCGT TGTCCCCAGCTGTATGGTCCTGGGCAGCATGTGTAAATGATTTAATATTTTCTTTCTTCT TTGCAAAATGGGATAGGGAGAGTTTCTCTGGTGATGAAATGCGATCATAGTGGCATAGGA GGTAGCGCATGCCCATCACGGTGTAGCTGCTCAGAGTGCTGCCTCTCTCATTGCTGATCC ATGTCCTGATTCCTTCCCAGCTTCCTGACACTAAGGATGAGTATAAGATAGATGCTATTG TCATCCCTGTTTTATAGACGAGGAACCAGGCTCACAGAGCTTAGATGACTTGCCCATGAT TACAGAGCCATTAATTGATGGAGCCTGGAATTGGACCGAAATTTGGCAACAGAGTTCTCT GCCTTTCCAGACCTGTTGATTTTGGTCTTTCAGACGTTGCTAGGAGAGCCCTGAAGTACT TGATCAGCCCAAGTCTGTAAGAGGGCATAAGAGCAGGTCCTGGTTGTGTTTGGCCCAGTC TGAGAGGGCCTAGAGTTAGAAGGTAGAGTGCACTTTGAGGAGTTTGTGGGCCAGGGTTAG CTCATCCCTCCCTGGGGTGGGGAGTGATCAGTTGGCAGCTGTGCCGGGAGAGGGAGCTGG TGGCCTGGGGCGCGGTGGTTGTGTATGAAGCTGGAGGCTTGGGCTCAGGGGAGACCTGAG CATGGGGAAGGAGCATCGTGAGCATGGTGGGAGTTGTGGCACTGTGGGGGGGGCTCATGG GGACCGTGTCCATCCTCCCTCCAGAATCTCCTGCTGTGTGTCCTAACTGTGGTAGTGACC ACGTGGTTCTCCTCGCTGTGTCTCGGGGAACCCCCAACAGGGAGCGGAAACAGGGAGAGC AGTCTCTGGCTCCTTCTCCGTCTGCCAGCCCTGTCTGCCACCCTCCTGGCCATGGTGACC ACCTTGACAGGGCCAAGAACAGCCCACCTCAGGCACCGAGCACCCGTGACCATGGTAGTT GGAGCCTCAGTCCCCGTGAGTATAGGCAAAACAAGACATAGATGAGTTTGGGGAAGGGAA GGGGCACTGATGGGGAGGTGGAGATGGAGCCCAGGGGCTGCCATGGGCAGGCTGATGCCC CCTCATTGCCCTCAGCCCCTGAGCGCTGTGGCCTCCGCTCTGTGGACCACCGACTCCGGC TCTTCCTGGATGTTGAGGTGTTCAGCGATGCCCAGGAGGAGTTCCAGTGCTGCCTCAAGG TCTGTGCTCCCTGACACTGCCCATGCCCCCAGCTGTCCAGGGTGCCCACTCGTTTCCATC ACAGCCAACTGAGTCAGATCAAGCACTCTAGAGACCTGATCTGGCTTCTGGTTTCAACCC CAGCAGCTTCTTGCTGTGTGGCCGTGGACACATTCCCTGGTATTTGAGTCCCAGTTGTTG CCTGTCTGCAATGGAGATAACGATGCCTCCCTTACACAGTGGCGTGCGTCAGGGCTCATG TTGAAGCTGCCCAGCCCAGCACCTGGCACTCATCAATGGGGCCTCCTAGCATTATTATAA ACACATGATGTCGTTAGGCCTTTGTTGAGCACCTGTTGTGCTAGACATTGAGGATCTACA GATCAATCTTGCCCTTGATCTTACAGTCTGGTGTGAGAAGCTGACAATGATTATGCAATA TGCAAATGCTGTAATCGGGCTAAGGCCCTTGAAGGGGTGTCTAGTCCAGCTTGAGTGGGT CAAGGAACCTTCCTGGGAGGTGATGTCTAAGCTCAGTCTTGAAGGGTAAGTTAAGGAGTA GGGAGGAAAAGAATGTCTTAGGTAAAGGAAGCCGCAAATGCATGGAGGCCCGAGAGTGTC GCTGGTGGGGAGAACTGCCCAGGATGAGGGCACCTGGACATGCAGGGCGAGGGGCAGGGG TCCTGAGAGGACTCTGGGGGGCCGGCAGGGGCCAGGTCAGGAGCTGCCTCCTGTGTCTGC CAAGGAGTTTGGACTTGTTTCTGAGGGCCACTGGGAGCCACTGAAGGATTTGAAATGGGG CAGTGATGGTCAGTTTTGTGCCTTAGAATAGTTAGTCTGGCGGAGCGTGGAGGGGGTGAG GCGACAGGCAGGGAAGCCAGCTGCTGAGGCTCTGAGCGGGCAGGGGCTGCAAGGCAGAGA GCGGTGGTGGATGAAGAGGCTGTCGAGTGTGAGGGAAGCTCCATAGACTGGTGGGTGGGC AGTGGGAGGGTCAGGCCGAGGGTGCTGTCACCAGGAACTCGGCTTTCAGTCTGGCCCCAC CTCCCCAGGCCTCTCATCAGGTTTCTCACCAACTTCCTCTTCCCCCAGGTGCCAGTGGCA TTGGCAGGCCACACTGGGGAGTTCATGTGCCTTGTGGTTGTGTCTGACCGCAGGCTGTAC CTGTTGAAGGTGACTGGGGAGATGCGGTGAGTGAGAGGGGAGATGCAGTGAGTAAGGGGG GAGATGGGGTGAGTTGGGGGGAGATGGGGGAGTGAGGGGGAAGATGGGGTGAGGGGGGAG ATGGGGTGAGTGAGGGGGGAGATGGGGTGTTAAGGGGGGAGATGGGGTGAGTGAGGGGGG AGATGGGGTGAGAGAAGGGGGAGATTGGGTGAGTGAGGGGGAGGTGGGGTGAGTGAGGGG GGAGGTGGGGTGAGTGGGGGGGAGGTGGGGTGAGTGGGGGGGACGTGGGGTGAGTGAAGG GGGAGATGGGGTGAGTGGGGGGCGGAGATGGGGTGAGTGGGGGGCGGAGATGGGGTGAGT GAGGGGGGAGATGGGGTGAGTGAGGGGGAGATGGGGTGAGTGAGGGAGGAGATGGAATGA GGGGGAAGATGGGGTGTGGTGAGCGCACGGGGGTGATGCAGTGAGTGAGGCAGGTGCAGC TGGGGCAGGGCCTCTCTGGGACTCTCACTCCACTCTCATGCTTCTCCATTGCTCTGTCCC CTCTCTCCACAGTGAGCCTCCAGCTAGCTGGCTGCAGCTGACCCTGGCTGTTCCCCTGCA GGATCTGAGTGGCATAGAGCTGGGCCTGGCAGGCCAGAGCCTGCGGCTAGAGTGGGCAGC TGGGGCGGGCCGCTGTGTGCTGCTGCCCCGAGATGCCAGGCATTGCCGGGCCTTCCTAGA GGAGCTCCTTGGTGAGAGAGGGGAGGGGAAGGCAGGAGGGTGGGCAGGAGGGTGGGCAGG GCCTTGGGGCCAGGCTCCCCACCTGGTACCCAGTAGCGGAGACAGAGAGGTAACAGGACT TGTCCCTTGTAGAAGTTTCTGAAATCCAGAAATGTGGAGAATAGGAAGGGATTGAGAGGT GGTGAGTTTAGGCTGGAGGAGAGCAGAGCCTTCTAAAGTTCCCTGGCCTGCCTCTGTCTA GATGTCTTGCAGTCTCTGCCCCCTGCCTGGAGGAACTGTGTCAGTGCCACAGAGGAGGAG GTCACCCCCCAGCACCGGCTCTGGTGAGTCGATAGGAGGCAGAGGCTGGGGTTGCTGCCC AATCCTCTTTCCACAGAGCCCCAGACATGGCCCTGTGCTGAGTAGGTCCTGGGCAGCCAC CTGTCCTCATGCCATGCCCCTTATGGGCCCCTAGTGTCTCCTCCCAACCCCCTGCAGGGC TTTCTTCCCACTCCCCTCTCTTCAAGTCCTTCCCACCCGCTAGCTGATCTTCCTGTGCCT GCCATATTCCCTCTAGGCCATTGCTGGAAAAAGACTCATCCTTGGAGGCTCGCCAGTTCT TCTACCTTCGGGCGTTCCTGGTTGAAGGTGAAGCCTCTGTGCAGCTGATGCTTCCCTGGT CTCTGTACCCTACCTTGTCACAGGCACTGGCCCACGCGCAGCACCTGTACAGTGCCCTTG CAGCAACTGTCAGTTCCTGGAACCTGGAGAACCTCTCACTTGAGGGCATAGCTGAGTAAC AGCCTCAGTGTGCCCTGACCCTCTGGGTGGGGTTAGGAGGCACCCAGGATCCTCAGTTAC CCAGAGCCTTTGCTCTCGGGCCCAGGCTTTCTATGAAGTGGAGCAGCGTGGCTGAGTCGG CCCTGCCTCATCAGTCACAGAAGGAGAGGGTGGAGCCTTGTTTCTGAGTAGGGTGGGTGT GGGGCAGTGGGGGGCGGTAGGCCTCAGAGGTATTCCAGAGTAGAGATTCATGGAGCTTGG GAAAGGGAGGGTCTTGGCCCCAGGGGCACAGGCTGCTTTGTGACCCACCTCAGAGTGTGG TTCACACCTCTTCTCCCCAGCAGCACTGGGACGCTGGCCCCAGGGATCTGGGCCCCTCCA TGACCTTCCACACTGGATGCCTCTTTCCCTGCAGGCCCTTCCACCTGCCTCGTATCCCTG TTGCTGACTCCGTCCACCCTGTTCCTGTTAGATGAGGATGCTGCAGGGTCCCCGGCAGAG CCCTCTCCTCCAGCAGCATCTGGCGAAGCCTCTGAGAAGGTGCCTCCCTCGGGGCCGGGC CCTGCTGTGCGTGTCAGGGAGCAGCAGCCACTCAGCAGCCTGAGCTCCGTGCTGCTCTAC CGCTCAGCCCCTGAGGACTTGCGGCTGCTCTTCTACGATGAGGTGTGTATGTGTATCTCC AGTGAGAGGGAGGGAGGGGAGATGGTGAGCACAGGTTGGGGCCATGAGGGCAGGGTGGGA AATGGGTCTAGGAACCCTGGGCATTGGTGGCAGGATGGCACTTACAGATGAGAGAACTAG GGTTGGAGGAACTGGGGGACTCTAGGCTTGGATGAATATCAAGTCAGGGAGGCAGCTGTA GGCAGGGGAGACACCTGGACTGGGAGCCCAGCCATTTAGCTGGGCCACGAGGCTTTCAGT GAGGTTTCCGGCAGCTTTGAGTTGGCAGGATTGGGCCGGTTGTATGCCAGCCGTTTGGCC TTTGTGACCACCACCTGAGGAGATACGGTTACTGGTCCTATTTACAGGTGAGGAAGCTGA GGCTTGGGGATGTTAACCAGTTTGCCCAGTCCAAAGTGGTGGAGCCGGGAATTGAATCCA CAGTTCCCTGAAATTGAGCCCGCATCTTCTGTACAACAGGGAAGATGAAAAAGACAGGTC CTCTGGAGGCTTTCAGTAAACGTCGGCTGGATTCTGTTTACAAAGCTCAGAGTCAGGATC TTTTATGGGGAGTGACATGGGCCTGGGGAAGGGGAGAGGCACTGAGCCAAGGTGGAGACA GTGAGGCCTTCGCAGAGACCTCCCTTGTACCCACCCTGGTGTGGTCCCCATGAGCCTCGC CTTGCTAACTGCTCGGTCTGCCAGGTGTCCCGGCTGGAGAGCTTTTGGGCACTCCGTGTG GTGTGTCAGGAGCAGCTGACAGCCCTGCTTGCCTGGATCCGGGAACCATGGGAGGAGCTG TTTTCCATCGGACTCCGGACAGTGATCCAAGAGGCGCTGGCCCTTGACCGATGAGGGTCC CACGCTGACCTTGGCCCTGACCTCAGGAGCCACGCTGTAGACATTCCCTCTCCTGGTCTC TGGGTCTGGCTTCCAGGCTCTGGCTGTGGATGTCTTCAGCCTCTGGGTGCTGGCCAGTGA GGTCCCAAATGACCCAGGGCTTAAGGGAGAGGCGAGAGAATGATCTGGCCTCAGGGGACA GGCCACCTGGTCAGGAGGAATATTTTTCCTGCACTTTTTCTCAGGTATCAATAAAGTTGT TTCCAACTCATAGGTCATGTGTGGTACTTAGA bcftools-1.21/test/csq/ENST00000295641/ENST00000295641.fa.fai000066400000000000000000000000211467060157400215360ustar00rootroot000000000000002 18632 25 60 61 bcftools-1.21/test/csq/ENST00000295641/ENST00000295641.gff000066400000000000000000000174411467060157400211720ustar00rootroot000000000000002 ensembl_havana gene 21 18612 . + . ID=gene:ENSG00000144589;Name=STK11IP;biotype=protein_coding;description=serine/threonine kinase 11 interacting protein [Source:HGNC Symbol%3BAcc:19184];gene_id=ENSG00000144589;logic_name=ensembl_havana_gene;version=16 2 ensembl_havana transcript 35 18612 . + . ID=transcript:ENST00000295641;Parent=gene:ENSG00000144589;Name=STK11IP-201;biotype=protein_coding;ccdsid=CCDS46521.1;tag=basic;transcript_id=ENST00000295641;version=10 2 ensembl five_prime_UTR 35 77 . + . Parent=transcript:ENST00000295641 2 ensembl exon 35 84 . + . Parent=transcript:ENST00000295641;Name=ENSE00002345772;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002345772;rank=1;version=1 2 ensembl CDS 78 84 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 255 341 . + . Parent=transcript:ENST00000295641;Name=ENSE00003482150;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003482150;rank=2;version=1 2 ensembl CDS 255 341 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 3396 3601 . + . Parent=transcript:ENST00000295641;Name=ENSE00003658740;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003658740;rank=3;version=1 2 ensembl CDS 3396 3601 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 3802 3876 . + . Parent=transcript:ENST00000295641;Name=ENSE00003678323;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003678323;rank=4;version=1 2 ensembl CDS 3802 3876 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 4149 4244 . + . Parent=transcript:ENST00000295641;Name=ENSE00003608784;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003608784;rank=5;version=1 2 ensembl CDS 4149 4244 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 4629 4736 . + . Parent=transcript:ENST00000295641;Name=ENSE00003635082;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003635082;rank=6;version=1 2 ensembl CDS 4629 4736 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 4866 4937 . + . Parent=transcript:ENST00000295641;Name=ENSE00003541596;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003541596;rank=7;version=1 2 ensembl CDS 4866 4937 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 7769 7895 . + . Parent=transcript:ENST00000295641;Name=ENSE00003554953;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003554953;rank=8;version=1 2 ensembl CDS 7769 7895 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 8117 8220 . + . Parent=transcript:ENST00000295641;Name=ENSE00003545281;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003545281;rank=9;version=1 2 ensembl CDS 8117 8220 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 8356 8451 . + . Parent=transcript:ENST00000295641;Name=ENSE00003571920;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003571920;rank=10;version=1 2 ensembl CDS 8356 8451 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 8637 8678 . + . Parent=transcript:ENST00000295641;Name=ENSE00003467019;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003467019;rank=11;version=1 2 ensembl CDS 8637 8678 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 8873 9019 . + . Parent=transcript:ENST00000295641;Name=ENSE00003558977;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003558977;rank=12;version=1 2 ensembl CDS 8873 9019 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 9214 9298 . + . Parent=transcript:ENST00000295641;Name=ENSE00003608694;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003608694;rank=13;version=1 2 ensembl CDS 9214 9298 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 10208 10591 . + . Parent=transcript:ENST00000295641;Name=ENSE00003603489;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003603489;rank=14;version=1 2 ensembl CDS 10208 10591 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 10744 10949 . + . Parent=transcript:ENST00000295641;Name=ENSE00003655116;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003655116;rank=15;version=1 2 ensembl CDS 10744 10949 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 11258 11374 . + . Parent=transcript:ENST00000295641;Name=ENSE00003537785;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003537785;rank=16;version=1 2 ensembl CDS 11258 11374 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 11524 11701 . + . Parent=transcript:ENST00000295641;Name=ENSE00003107623;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003107623;rank=17;version=1 2 ensembl CDS 11524 11701 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 13765 13995 . + . Parent=transcript:ENST00000295641;Name=ENSE00002387596;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002387596;rank=18;version=1 2 ensembl CDS 13765 13995 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 14116 14219 . + . Parent=transcript:ENST00000295641;Name=ENSE00002356818;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002356818;rank=19;version=1 2 ensembl CDS 14116 14219 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 15289 15386 . + . Parent=transcript:ENST00000295641;Name=ENSE00002425663;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00002425663;rank=20;version=1 2 ensembl CDS 15289 15386 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 15913 16091 . + . Parent=transcript:ENST00000295641;Name=ENSE00003510227;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003510227;rank=21;version=1 2 ensembl CDS 15913 16091 . + 1 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 16322 16403 . + . Parent=transcript:ENST00000295641;Name=ENSE00003460397;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003460397;rank=22;version=1 2 ensembl CDS 16322 16403 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 16637 16707 . + . Parent=transcript:ENST00000295641;Name=ENSE00002417904;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002417904;rank=23;version=1 2 ensembl CDS 16637 16707 . + 1 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 17255 17502 . + . Parent=transcript:ENST00000295641;Name=ENSE00002415358;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002415358;rank=24;version=1 2 ensembl CDS 17255 17502 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl CDS 18205 18354 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 2 ensembl exon 18205 18612 . + . Parent=transcript:ENST00000295641;Name=ENSE00001461605;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001461605;rank=25;version=1 2 ensembl three_prime_UTR 18355 18612 . + . Parent=transcript:ENST00000295641 bcftools-1.21/test/csq/ENST00000295641/not-a-start-lost.txt000066400000000000000000000002131467060157400225400ustar00rootroot0000000000000079 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T 79 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T bcftools-1.21/test/csq/ENST00000295641/not-a-start-lost.txt-l000066400000000000000000000002131467060157400227710ustar00rootroot0000000000000079 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T 79 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T bcftools-1.21/test/csq/ENST00000295641/not-a-start-lost.vcf000066400000000000000000000005161467060157400225050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 79 . G T . . EXP=missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T;type=ENST00000295641:220462640-G-T bcftools-1.21/test/csq/ENST00000301246/000077500000000000000000000000001467060157400166405ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000301246/15bp-insert.txt000066400000000000000000000005251467060157400214540ustar00rootroot00000000000000770 G GAAGAAGGAGAAGGGC 3_prime_utr|C19orf33|ENST00000588605|protein_coding,inframe_insertion|C19orf33|ENST00000301246|protein_coding|+|89K>89KKKEKG|770G>GAAGAAGGAGAAGGGC 770 G GAAGAAGGAGAAGGGC 3_prime_utr|C19orf33|ENST00000588605|protein_coding,inframe_insertion|C19orf33|ENST00000301246|protein_coding|+|89K>89KKKEKG|770G>GAAGAAGGAGAAGGGC bcftools-1.21/test/csq/ENST00000301246/15bp-insert.vcf000066400000000000000000000010331467060157400214060ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 19 770 . G GAAGAAGGAGAAGGGC . . EXP=3_prime_utr|C19orf33|ENST00000588605|protein_coding,inframe_insertion|C19orf33|ENST00000301246|protein_coding|+|89K>89KKKEKG|770G>GAAGAAGGAGAAGGGC;type=ENST00000301246:38795550-G-GAAGAAGGAGAAGGGC bcftools-1.21/test/csq/ENST00000301246/ENST00000301246.fa000066400000000000000000000016411467060157400207630ustar00rootroot00000000000000>19 19:38794781-38795669 GAGGTTGGGTGGGGCGTCTCAGCATTCCTCCAACGGGCAGGTCTCAGCGCTCCTCCCCCT GCTCCGCTCCTCTGCAGGGCCCAGGCGCCCTTGGCCTTAGGACCCAACTTCTCTTACCGC CATGGAGTTCGACCTGGGAGCAGGTGAGCTCCTGGGGAGTGTGGACTGGAGGTGCAGGGG GCCGGACTCAAGCCCAGAAGCTGCCTGCACCAACCACCCAACTTCTCTCCACAGCCCTGG AGCCCACCTCCCAGAAGCCCGGTGTGGGGGCGGGCCACGGGGGAGATCCCAAGCTCAGTC CCCACAAAGTTCAGGGCCGGTCGGAGGCAGGGGCAGGTCCGGGTCCAAAGGTAAGTCGCC TCATCACCGGCTGCGGAGGGGCGGGAAGGCTGGGGTTGCCCCTGACCCCAGGGTCCTGCC TTAGGCCTCCAACTTCAGGGGGCTGGGTAAGGGGCGCCGCCTCACTGCCGCACCTCCATC CAGCAAGGACACCACAGCTCTTCCGACTCCAGCAGCAGCTCCAGCGATTCGGACACGGAT GTGAAGGTAAGGGGCTCTCGCCAGCGTCCCCAAGCACGTGCCCTGCACCCCAGAGAGGCG TCCCCGCACTGGGGCTGGCGGGGAGGGTGCGGGGAGTGGTCCCCCTGTCTCGCTTCCAGC CCAGAACCATCTCTTCTCTCCCATCCCTGCCCTCGGCCCCACAGTCCCACGCTGCTGGCT CCAAGCAGCACGAGAGCATCCCGGGCAAGGCCAAGAAGCCCAAAGTGAAGAAGAAGGAGA AGGGCAAGAAGGAGAAGGGCAAGAAGAAGGAGGCTCCCCACTGAAGGGCCCTGGACAGGG CTCATTAAACCTTCCTCTCTGCCTTCTGCGACTGGTCAGCGTGGTGCCT bcftools-1.21/test/csq/ENST00000301246/ENST00000301246.fa.fai000066400000000000000000000000201467060157400215070ustar00rootroot0000000000000019 889 25 60 61 bcftools-1.21/test/csq/ENST00000301246/ENST00000301246.gff000066400000000000000000000065021467060157400211400ustar00rootroot0000000000000019 ensembl_havana gene 21 869 . + . ID=gene:ENSG00000167644;Name=C19orf33;biotype=protein_coding;description=chromosome 19 open reading frame 33 [Source:HGNC Symbol%3BAcc:16668];gene_id=ENSG00000167644;logic_name=ensembl_havana_gene;version=7 19 ensembl_havana transcript 21 869 . + . ID=transcript:ENST00000301246;Parent=gene:ENSG00000167644;Name=C19orf33-001;biotype=protein_coding;ccdsid=CCDS12511.1;havana_transcript=OTTHUMT00000458168;havana_version=1;tag=basic;transcript_id=ENST00000301246;version=5 19 ensembl_havana five_prime_UTR 21 121 . + . Parent=transcript:ENST00000301246 19 ensembl_havana exon 21 143 . + . Parent=transcript:ENST00000301246;Name=ENSE00002964887;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002964887;rank=1;version=1 19 ensembl_havana CDS 122 143 . + 0 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 19 ensembl_havana exon 235 350 . + . Parent=transcript:ENST00000301246;Name=ENSE00003679241;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679241;rank=2;version=1 19 ensembl_havana CDS 235 350 . + 2 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 19 ensembl_havana exon 484 546 . + . Parent=transcript:ENST00000301246;Name=ENSE00003669537;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003669537;rank=3;version=1 19 ensembl_havana CDS 484 546 . + 0 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 19 ensembl_havana CDS 705 824 . + 0 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 19 ensembl_havana exon 705 869 . + . Parent=transcript:ENST00000301246;Name=ENSE00002868661;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002868661;rank=4;version=1 19 ensembl_havana three_prime_UTR 825 869 . + . Parent=transcript:ENST00000301246 19 ensembl_havana transcript 24 866 . + . ID=transcript:ENST00000588605;Parent=gene:ENSG00000167644;Name=C19orf33-002;biotype=protein_coding;havana_transcript=OTTHUMT00000458169;havana_version=1;tag=basic;transcript_id=ENST00000588605;version=1 19 havana five_prime_UTR 24 121 . + . Parent=transcript:ENST00000588605 19 havana exon 24 143 . + . Parent=transcript:ENST00000588605;Name=ENSE00001309662;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001309662;rank=1;version=3 19 havana CDS 122 143 . + 0 ID=CDS:ENSP00000464940;Parent=transcript:ENST00000588605;protein_id=ENSP00000464940 19 havana exon 235 350 . + . Parent=transcript:ENST00000588605;Name=ENSE00003679241;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679241;rank=2;version=1 19 havana CDS 235 350 . + 2 ID=CDS:ENSP00000464940;Parent=transcript:ENST00000588605;protein_id=ENSP00000464940 19 havana CDS 425 544 . + 0 ID=CDS:ENSP00000464940;Parent=transcript:ENST00000588605;protein_id=ENSP00000464940 19 havana exon 425 546 . + . Parent=transcript:ENST00000588605;Name=ENSE00003656115;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003656115;rank=3;version=1 19 havana three_prime_UTR 545 546 . + . Parent=transcript:ENST00000588605 19 havana exon 705 866 . + . Parent=transcript:ENST00000588605;Name=ENSE00001323608;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001323608;rank=4;version=4 19 havana three_prime_UTR 705 866 . + . Parent=transcript:ENST00000588605 bcftools-1.21/test/csq/ENST00000303039/000077500000000000000000000000001467060157400166425ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000303039/ENST00000303039.fa000066400000000000000000000021351467060157400207660ustar00rootroot00000000000000>11 11:56127691-56128764 TCCCCCAAACAGATGAATTTCCAAACTCTGACATGGCTCCTGAAAATTTCACCAGAGTCA CTGAGTTTATTCTTACAGGTGTCTCTAGCTGTCCAGAGCTCCAGATTCCCCTCTTCCTGG TCTTTCTGGTGCTCTATGGGCTGACCATGGCAGGGAACCTGGGCATCATCACCCTCACCA GTGTTGACTCTCGACTTCAAACCCCCATGTACTTTTTCCTGCAACATCTGGCTCTCATTA ATCTTGGTAACTCTACTGTCATTGCCCCTAAAATGCTGATTAACTTTTTAGTAAAGAAGA AAACTACCTCATTCTATGAATGTGCCACCCAACTGGGAGGGTTCTTGTTCTTTATTGTAT CGGAGGTAATCATGCTGGCTTTGATGGCCTATGACCGCTATGTGGCTATTTGTAACCCTC TGCTGTACATGGTGGTGGTGTCTCGGCGGCTCTGCCTCCTGCTGGTCTCCCTCACATACC TCTATGGCTTTTCTACAGCTATTGTGGTTTCATCTTATGTATTCTCTGTGTCTTATTGCT CTTCTAATATAATCAATCATTTTTACTGTGATAATGTTCCTCTGTTAGCATTATCTTGCT CTGATACTTACTTACCAGAAACAGTTGTCTTTATATCTGCAGCAACAAATGTGGTTGGTT CCTTGATTATAGTTCTAGTATCTTATTTCAATATTGTTTTGTCTATTTTAAAAATATGTT CATCAGAAGGAAGGAAAAAAGCCTTTTCTACCTGTGCTTCACATATGATGGCAGTCACAA TTTTTTATGGGACATTGCTATTCATGTATGTGCAGCCCCGAAGTAACCATTCACTGGATA CTGATGATAAGATGGCTTCTGTGTTTTACACGTTGGTAATTCCTATGCTGAATCCCTTGA TCTACAGCCTGAGGAATAAGGATGTGAAGACTGCTCTACAGAGATTCATGACAAATCTGT GCTATTCCTTTAAAACAATGTAATTTTAAACAGTACAGGTAAATGAGGAGAGAGTTAATA TAAGCTGCCATTATGTAAAAGAAAATGTAGGAAAAAGAAAAGGTAGGTAGCCGA bcftools-1.21/test/csq/ENST00000303039/ENST00000303039.fa.fai000066400000000000000000000000211467060157400215140ustar00rootroot0000000000000011 1074 25 60 61 bcftools-1.21/test/csq/ENST00000303039/ENST00000303039.gff000066400000000000000000000017341467060157400211460ustar00rootroot0000000000000011 ensembl_havana gene 1 1074 . + . ID=gene:ENSG00000172487;Name=OR8J1;biotype=protein_coding;description=olfactory receptor%2C family 8%2C subfamily J%2C member 1 [Source:HGNC Symbol%3BAcc:14855];gene_id=ENSG00000172487;logic_name=ensembl_havana_gene;version=3 11 ensembl_havana transcript 1 1074 . + . ID=transcript:ENST00000303039;Parent=gene:ENSG00000172487;Name=OR8J1-001;biotype=protein_coding;ccdsid=CCDS31529.1;havana_transcript=OTTHUMT00000391606;havana_version=2;tag=basic;transcript_id=ENST00000303039;version=3 11 ensembl_havana five_prime_UTR 1 32 . + . Parent=transcript:ENST00000303039 11 ensembl_havana exon 1 1074 . + . Parent=transcript:ENST00000303039;Name=ENSE00001172518;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001172518;rank=1;version=3 11 ensembl_havana CDS 33 983 . + 0 ID=CDS:ENSP00000304060;Parent=transcript:ENST00000303039;protein_id=ENSP00000304060 11 ensembl_havana three_prime_UTR 984 1074 . + . Parent=transcript:ENST00000303039 bcftools-1.21/test/csq/ENST00000303039/not-a-stop.txt000066400000000000000000000001651467060157400214060ustar00rootroot00000000000000983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding 983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding bcftools-1.21/test/csq/ENST00000303039/not-a-stop.txt-l000066400000000000000000000001651467060157400216370ustar00rootroot00000000000000983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding 983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding bcftools-1.21/test/csq/ENST00000303039/not-a-stop.vcf000066400000000000000000000005421467060157400213440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 11 983 . A AT . . EXP=3_prime_utr|OR8J1|ENST00000303039|protein_coding;type=ENST00000303039:56128673-A-AT, 983 is the last base of CDS bcftools-1.21/test/csq/ENST00000318249.2/000077500000000000000000000000001467060157400170135ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000318249.2/ENST00000318249.2.fa000066400000000000000000001311211467060157400213060ustar00rootroot00000000000000>1 1:21766621-21811498 GGCGCAGGCACAGGCGAGGGGTTGGGTGGCGGTTGAGACAGCGGCGGTACTGGGATGGGT AGGTGAGGATCCCGAGACTGAGTGAGCTTCTGCGCGCGGTGCTTTTGGGAACGCGGGACT GGCAACCTGCGGCGCCAGGAGCTGGGCCGAGGCGCGGCGGCGCGGCTGCGGGCCGCCGTC TGGATGGGAAGTTACGGCGAAGTCCACCCAGCGTTTCTCAGGTGAGGGCGCCGCGCCAGG CTGGACGGGCGGTGAATCCGGGACCGGCGGGCGCACACCTGGGTCGAGGCGCGGCCGTCG CAAGTTTTGTTGCGCGAGCGCGGGGGCGGGTGGGAGGTGGGGGGTGTGGGGGGTCGTGCA CCGCCGGGGGCTGAGTTCCCCGCGCTGGATTCTTCGCCTGCCGCTGCCGCCCTCAGCCCA GCTCTCGTGGGCGCTGGGGAAGAAACTCGCTGGCGGGTGTTCTGTGGCATCCCAGGGGGT GGAGGGACGGAGCAGCTTCGGGGGCACGTCCTCCTATATCCTGTAGAGGACACTGACTCC GCACCCCACCCTCGAGGCCGGAAATCGGTTCCCTCTGCGGGCCTGAGAGGCGAGAGCGCT CGCGCCCCTGACTTGCAAAGTTGGGGTCTTTACTGGCCTCCGGGCTTCTGCTCCTGGCGG TGTCTCCAGGCTGGTGATGGGCAAGCCAGGTGTGCCAGGTCCAGGATGCACATGAGGAGC GTTTGTAGCCATCACTGAATCACCTCCTGACTAGCGGGGCAAGCCTCAAATGAACCGCAG GATTTCGGCTAGGTTGGATTGTGGGGTTGCTGTTTGCACTCCGAGGAGTTGCTGTGGTTT CCCTGTGCCTGTCTGTCTGTCTTTCTGGCTTCTTAGATCATCATCTCATGTGGCGTCCTT TCACCGAAGAGTTAACCAAGACGTTTGGCCTAGTTTCCTTGCTTTCCTTCTGTCTTTTGC TGCTAGAGCTGCTTTCGAAAAGAAGTCTTTTCTGGCAGTGGTACCTTTTCTTTGGGTTAC GGTGTTGTTCATCCTTTCTTTGCCAAAGGAATGAATCCCAGTGCTTCACGAAGTTAAAGA TCTGCTGGTAGTGTTTAATCTGTTTGGAGCTGATATGCGTTAGTAGCTTTCTTTTTGTTT TTAAATTTTATTAGTAAAATTTCACTAGTGAACCAGAAGCTATTTTTTTCTATTCTGAAA TGCTGGCTTTAAGATTTCTGATAACTTTGCGTCAAAGAAATCTTGGAAAAGTTACTGAAG TATACAGAAGAAGTTCACAATTTTAAATGTGCAGGGGGCCCGGGCGCAGTAGATCACACC TGTAATCCCAGCACTTTGGGACGCCAAGGTGGGTAGATCACTTGAGCCCAGGATTTCCAC ACTAGCCTCGGCAATGTGGCAAAACCCTATCTCTACTAAAAATACAAAAGTTAGCTGTGT GTGGTGGTGTGTGCCTGTAGTCCCAGCTACCCGGTAGGCTGAGGTGGGAGGATCACCAGA GCCCGGAAGGTTGAGATTGCAGTGAGCCGTGATCATGGCAGTGCACTCCGACCTGGATGG CAGAGTGAGAGCCTATCTCAAAAAAAAAAAAAAAAAAAGTAATGAATTTTGACCAAGTGA ACCACCACAGATCAAGAAATAGAACATTACTAGACTGGAGTATATTTTTGGAGTGGCATT GTTGGTTTTAGAGGTATATGAATGATAAAACTTTAGTATTACATATTGTTGAACATTTTC CCAAAGTGGTTGTACCATTTAGCAAGGATATTCTGGTTACCCCACATCCTCGCTGATGCC TGTCAGTTAAAAATCATTTTGCCATTCTAGTAGGGGTGCAGTAATATATCAGTGTGGTTT CATTGAGATTGAGTATCTTTTATTGCCATTTATGTGTCTTCTTTTGTGACATGCCTGTTA AACCTTTTTATCCAGTTTTCATTGATATGCTTGTTTTCCTGTTGATTTGTAATACTTTAT TCTGGATATGCCTCCTTTCTAGGATTTATATGTATTGCATTTCCCTTTTTTCAATCTGTA GCTTGCGTTTTCACTCTTTTATGTTGTTTTTTCATGAATGGAGATTCTCTGTTTTTTTTC TTTTTGAAACAGGATCTCACTCCATTGCCCAGGCTGGAGTGCAGTGGCACAATCACAGCT CACTGCAACCTTGACCTCACAAGGCTCAGATGATCCCCCTGCCTCAGCCCCCAAGTAGCT GGGACCTACAGGGGAGTACCACCACACTCAGCTGTTTTCTGTATTTTTAGTAGAGATGGG GTTTTGCCACATTGCATAGGCTGGTCTGGAATTCCTAGGCTCAAGTGATACACCTGCTTC GGCCTCCCAAAGGATTGGGATTACAGGCATGAGCCACTGCACCCGGCCTGAGATTCTTAA TTTTAATGAAATTATACTTTATCAATCTTTTCCTTTATGGTTACTGCTTTTCATGTCATC TTTAAGAAATCAATGCCTAACCTAAGAGTATGAACACATTTTTCTGTGTTAACCTTATAA CAATTTTATTTCAGTTTTTGCATTTTTTTTTTTTCAGACAGGGCCTCACTCTATTGCCCA GGCTAGAGTGTGGTGGCAGGATCTCAGCTCACTCAACCTCCATCTCCTGGCTCAAGTGAT CCTCCCACCTCAGCCTCCTGAGTAGCTGCGACTATAGGCATGTGCCACCATGCCTGGCTA ATTTTCGTATTTTTTGTAGAGATGGGGTTGCAACATGTTTCCCAGGTTGGTCTCGAACTC TTGGGCTCAAGTAATCTGCCCGCTTCAGCCTCCCAGAGTGCTGGAATTACAGGTGTGAGC CACCCCACCTGGCTATGATTCACTTTTTACTACATGGATGTGTCTGCTTTATCCAGGACC ATTTATTGAAAAGACCATCCTTTTCCTTCTGCACCATGTGGCACTTTTCTTCATAAATCG ATTGACTGTATGGTCATCTGATTTATGAAATTAGTGTGGGTCTGTTTCTGTTTCTGGACC AACCTGGGTAACATAGTGAGATCCTGTCTCTACAAAAGATAAAAATAATAAATAAATGAA TAAAATTTAAAAAATAAGTGCATAGAGCAGATGGAGTCATAGGTGATAATTTATAAATGA TTGTCAGTTTCTTGGCTACATACAGGTGTTGGTAATTCAGATGTGTTGGGCGTTCAGGCA AAATGTATTAAGTGAATTATATGGTGTTCAGAATGATTGCTAGAGGTTCACTGTGACTTC AATTAGATGTTATTTGAGCCTCACAGAGCTGCAGTTTTGACTCTTTTATTTATTTGTCTT TTTGAAGTTTTTACAATCTTCCTGTCAAGGCAGTAACACTTTTATACTTAATTGTTCTTA GGTATACTTAATTAGCGAGAAAACTTTATGGATCATCCCTAAATAAGTGTTAAGCCATTT AAAGGGCTCACGTGATGTGATATAAACAATAGTATTCTACATAATAGTTTTAGGACTACA TAGAATAATTTTTTTTTTTTTCTTGAGACAGTGTCTCGCTCTGTTGCCCAGGCTGGAGTG CAGTGGTATGATCATGGCTCTCTGCAGCCTTGATCTCTCAGGCTCAAGCAGTCCTCCCAC CTCAGCCTCCTTAGTAGCTGGGTCTACAGGCATGCACCACTATGCCTGGCTAATTTTCTC CTTTTTGTAGACAGGGTTTTCCTGTAGTGCCCAGACTGGTTTCAAACTCCTGGGCTGAAA TGATCCTCCCACCTTGGCATCCCAAAGTGTTGGGATTACAAGCATGAGCCATCACACCTG GCCATTTTAGTTTTAATAATTTTTATGTTTTTCTAATTTAAAAGATTTACTAAAATCTCT TACGGCTGTTATTTATGAATATAGTATTCATTGTTGTTATTATGATGATTTTGTATGTGT TCAATCTGATTTTCAATATAAGCTACCGGCAATTAGAGATTTTGTCTCTTTTATTCACCA CTGTATTCTCAGTACTTGACCTTGCCTGGCATGAAACAGATATTGAATAAATATTTCTTA AAAGAATGAATGAATGAACATACTAATACCATATTCAACAATCTCCAAGTATCACAGTTT TCACCATCTAACAAATAAAATAGCTGTATAGAGTAGAGTCACAGTCAACCTGCCATGAAA GGAAATGTCAATGAAAAATAAACCTTCGTATGTGTAGCTGCTAAGATTTTGGGGCTTTTG TTACTGTAGTATAACCTAGCGAAAGCTCAGTGAGGCAGCATATACAATATATGTGTACAG ATAGACCAGCTAGACCAGTAGATGAGATTCCAAAGATAGTTCAATAAGCATTAACTAACA ACACCCACACTCTCTTAATTCCCTAACAAAAATAATGGAATTCTTGTTCACTAAGATCTG CCTCAAATATTACTTTGTGAAAACTTCCCTGGCTACTCTAGTATTTAGTCAGGACTCTAT TTTTTTTCCCGCCGGGCTGGAGTACAGTGGTGCCATCATAGCTCACTAACCTCTAACTCA AGGCTCAAGGAATCCTCCTGCCTCAGCCTAAGGAATCCTCCTGCCTCAGCCTCCCGAGTA GCTGGGACTACAAGTGTGTGCCACCATGCTCAGCTTATTTTTCATTTTTTATTTTCCAAG ACGGGGTCTTACTATGTTGCCCAGGCTGGTCAGGACTGTTGATTACATATGACAGAAACC CAACCACCTCTAGTTCCCACCACCTTTCAACCTGCTCTTCCCTGGGTCTTCCCAGTCTCC GTAAATGGCAGCTCCATCCTTCAAGTTGCCGAAGCCCCAAATCTCAATGTTAACCTTGAT TTCTCTCTTTTATCTCACAGGCAATCTGAAGGCAAATCCTGTTTAGACCCAGGCGAAGGT TCCTGGTGACCCAGGCTCTCACCAGCCAATTGTCCCTTGCCGTCCTCCTGAGGGTATCTG GAGCTTCAGTGCTGTGTGCTCTTGGCCTCCACACTGGAGATGCCACTGACTCCCACTGTC CAGGGCTTCCAGTGGACTCTCCGAGGCCCTGATGTAGAAACTTCCCCATTCGGTGCACCA AGAGCAGCCTCACATGGTGTGGGCCGACATCAAGAGCTGCGAGATCCAACAGGTAAAAAT CCCGAGGCATTGCCAGCTCGGTGGGGTCAGAGAGTCCTCTTTCTATTATAACTCAGATGT GAAGGGAAGATGTCAAGGTCCCTAAACATTGCAGGGCCTTGCCTGGCATGAAACAGATAT TAAATACGTATTTGTTAAATGAATGAACAAATATCCACAGCCTGTGCCGCCCATGGCCTG CAGTGCCGTGGTCAGGTGGAAGTGATTTTACTTCAGGAGAGGACAGTGTTCTCTCCAGGA CTTTTCCTTACTAGCTAGATCTGCATCCCTCTCCCCGCTCTTCCCCTCTCACCCCCCATT CTCTGCCCCCATTTCTCTCTGTTTCCACCCTACTGTCCCCTTTCACCTGCTTTCTGCTCT TCAGCTTTGATGGCTCACCCCCTCCCTGTCCACCTGCATCCCCCAGGCTAAGGCTCCTAC ACTGTCCTGGGTGGGGAGATGTGTCTCGTTTTAGGCAGTGCCCTCTGGATGTGTCTAGGA TGGGGAAACATGGCTCAGTTGCCAGTATAATGGGTTAAAAGTGGCCACTTTTGAAGGCCT TTCCCACCTCCCATTCCAGAATCCTGTAGGACTTAGAATTTATGGGCCACAGTGGAATTC TTGGTTTCCCAGGACCTTGTGGTGGACACCTTCTTTCACTGAGCATTCATGGGGTGACTA TTAGGTACCAGGCCCTGCTCTGGGCTAGAGGCCCCACAATGAGTAAATCTCAGGTCAGTA CCCCACGGAACCCACCACTGCAGGCATTGAGAGGGGGAGAAAGAAAGGGGCATGGCCCGT TTGTGTTCTCCTCATGTGGTCGCCCACAGGTCCTGGGGGAGTAGGAGCCAGTGCAAGGAG AGAAGTCCAGTGAGAAAGGCAAATGGATGACATCAGACCCAGGGGCTGAGGTCCCCAGCT GCAGCTGGGTAGCTTCTGGAGTGGACAGGGAGCAACAGGGAAGTTCGTGGCCTGGTGTTC TGGGATGCATTGTCTCATCTCGTTCTTGTGAGCACCAGAACTTATCCAAAGACAAGACTC AGTGTCTCTGGCAACAGTGGGCCAGAGACAGAATGTGTGAATTTCAGAGGAGGAGGAAGG GGTTGTACCCCATGGAAACAGTATATGGTTTTACAGTAGCGCATCTTTCTCTAATAACTG GTTAGTGTGTTCCTGTTAATGGAAAATATTGGTGGTGTAAGTTTCCCCACTGTTCTCATC TTCATGTAAATTTGTTCATTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT TCCTTCCCTACTTCCCTCCAACTCTCTTTCTCTTTATTCTTTCCCTGCCTCCCTCCCACC CACCCTCCCTCCCTTTCTTCCTCCTTCCCTCCCTCCCTCCCTTCTTTCCTTTCTTCCTTT CTTCTTTTCCTTTCTCTCTCATGCTCTTTTTCTTTCCTTTTTGTTCTCTCTACTTTTTTG AAGAGATCACACTGTACTGAAACCTACATTATTTACCAAAATCTCCAGATCTGCTTCTGT CTTGCAGGCAGAGAGCTCATCCAGTAGCCCTTAGCTCTTCCCAGCCCCCTCCTTTGATTT GTGGGTGCCACTGGGGCAGCTGCTGAGTCTCAGTGGTTTCTAGTCTTCACCAAGTTCTGC CCACCCAGATGGTTTTTACCTCTCCTTACCAGAAACCTGCACTGTCTAGATTGCTGAGGC TGCTTCTCCTTAACCGATCTGCTATCTGTATTCCAGGGGCACCGCAGGGTTAGAGGTAAA TGGCACAGGCCTTGAAATCTCCAACTGCTCTGACTCCAGGTTGGTGCACTTCAATGCCAA GTACTAACCACCCAGTTACAGGATGCCACCAAAACCTTGATATGGGGCTGCTGCATCCTA ATTAAAACAAATTAATAGAATTTTTTTTAGAACAGTTCTAGGTTTGTGGAAAACTTGAGT GGATAGTACAGAGGGTTCTCCTAGGCTCCCCTGTCCTCCACACAATTTCTCCTATTAGTA TGTTTTATGAGTGTGGTCCATTGGTTACAATTGATGAACCACTGTTGATACATCATTATC CCCTAAAGTCCATAGTTTACATTAGAGTTCATTCTTTGAGTTTCACAGATTATGGGTTTT GGCAATTACATAATGTCCTAAATCCCCAATACAGCGTCATGCGAAATAGTTTCACTGCTG AAAATTCCCTGTGCGTCACCATTTCATGCGTCCTCCTCTCCTCCACCCCTGACAACCACT CATCATTTTACTGCTTCTTTTTGACTTTCCAAGAATGTCCTAGAGTTGGAATGGTACAGG ATGTGGGTTTCCAGACTGGCTTCTTTCTAGCATTATGTACTTTAAGTTCCTCCATGTCTT TTCATGGCTTGATAGCTTGTTTTTTAAAATCAGTGAATCATATTTCGTTGTATGGCTACA ACAGTTTCTTTATTCATTCACTTGGTGAAAGACATCTTGGGTACTTCCAAGTTTTGGCAA TTATGAATAAAATTGCTGTAAGTACTTCTGTGCAGGATTTTGAGTGAACTTGTTTTCCAA AGTGACAGTACCCTTTTGATTTCCACTAGCGATGGAAAGTTCTGGTTGCTCCTCATCTTT GACAGCATTTGGTGTGTTCACCTTTTTGAATTTTAGCCATTCTAATACAGTGATATCTCA TTGTTGTTTTAATATGCAATTCCCTAACGACAAATGATTTTGAGTGTCTTTTTCATATGC ATATTTGCCATCTGTATATCTTATTAATGAGGTGTTCAGATCTTTCACCTATTTTTTTTT CTTTGTGTTGTTTAGTTCTCAGAATTCTTCATATATTTTGGACAGCAGTTTTTCCATCAG ATTATTTTGTAAATATTTTCTGCCAGTCTGTGACTTGCTTTTTCCATTCTCTTGACAGTG TCTTTCACAGAGCAGAAGTTTTTAATTTTAATGAGGCTCAACTTAATTTTTTTCATTAGT AGATTGTGCTTTTGGTTTTGTATCTAAGAAGCCATCATCCAACCCAAGATCCCCAAGATT TTCTCTTATGTTATCTCCTAGGATTCTTATGGTTTTGCATCTTACATTTACATGTAAGAT TTATTTTATAAAGGGTATAACATGCATACCTGGATTTATTATTATTTTTTTTTTTTGCAT GTGTTTGTCCAGCTGTTCTAGCACCACTAGTTGGAAAGGCTGTCTTTGCTGTTTTAAATT GTCTCTAAACCTTCATGGACGATCAGTGGACTGTCTGTAGGCCTGTTTCTGGGCTCTGTA TTCCTTTTCCACGAATCTATTTGTGTGTGTTTTCTCTTTTCACCAACTTCACACTATTTG GGTTACTGTAGCTTAATGTAAGTCCTGAAGTTGATAGTGCCAGACGTCAGGGGGGTTTTC GGAACTTCATCATGAGAACCTGGTTGAGACCATTGTAGTAAAACTTGGAAACGTGTGAGA TTCCCCCTTAGTCTGGTTTTCAAGGAGTTTTTAATGCTCTAGCCAGGCCACCCTCAGCTT CTAGTAATCTGTCAATACCATTTAAGTGCTCCTCCCACTTGCTGTCCCCAGTAGCTTCTC TTCCCTGTGAGCTCTGACTCCTTGTGTGTTAGCCTGTCTTTCTCATTTTTAGGGTGGCCG TTTTCCCTGTGACCTCAATTCTCTGGTCCACCCTAGAAGGGTTGACTTTCAGTTTGTTCA GCTTTTTTCTAGCTGTGAGGACAAGTGATGACTGCCTAGCTCTTTCCATGTTGGAATAGA AACCCAAAAGTTCGTTTAAAGAATTACTTGTTATAAAAGTCAGCCATTGTCCACGTACAA CTCAATGACTTAAGGTGATATATAGAATTGTGCAGCCATCAGCAGAGTTCTACTTTAGCA CATTTTATCGCTTCCCCAAATTCCCTTGAACCTCTTTGTAGTCATTTCCTAATCCCTGGT CCCCATGACTGGGTCTGAATAGAATAAATATTTGGAAAGCAGACTTCATTATATTTACAT TTTCATGTGTTTGGGACTTTATATAGTGGACTATTGTGTTTGTTTTGTGACAAGCAGAGA AGAGATTGCATTCTAGGGATGTTTTTTGGGGAACATAACAGTAGTCTTGTTTATGGCTCT CCTTGAAATTGGTTCATCTGTGCTGGTGACTGGTATTTGCTACCAAACCTTGTCTGGTGA GCACAAGAAAATGAATTTTTAAAAATCTGCTATGAAAATCGAGATGATACATTTTCACAT AATAATATGTGGAGTTAAGTAACGAACCATCTTTATTTATTTATTTATTTATTTATTTTT TGAGATGGAGATTTTGCTCTGTTCCTCAGGCTGGAATGTAATGGCGTGATCTAGCTCACT GCAACCTCCACCTCCTGAGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGCGA TTACAGGCACCTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACATGGTTTC TCCATGTTGGCCAGGTTGGTCTCTAACTCTTGACCTCAAGTGATCCACCTGCCTTAGCCT CCCAAAGTGCTAGGATTACAGACATGAACCACGGCCTGACCTGAACCATTTTTATTCTTT CAGAAATGTGATTGATAACAGTAAAGCCACACTCCTCGCATGCCTGAAATACCCCTCATT GTCTTCTTCAGGTGGCAAGGGCTCTGAAACAGCCACATAAAGTTGAGGGCAATATTTTTA CTGTAGTTCTTTCATTGATTGATTGATTGATTGATGGATTGATTGATTTTTTCTCTGAGA GGAATTAGCATCCATGTATCTGAAATTGAAATTCAAGAGGAGAGACAGGCACCTGTACTA GTTTTCTCTTGCTGCCAATTATCACATTACCACAAACCAGTGGTTTGAAACCACAGAAGT CTGGAATGAAGCGGCTGGGTTCTCTGATCAGAGTCATGTGAGGCTAAAATTCAGAAATGG GCTGGCTGTGTTTTTTTTCTAGAGCTCAAGCTATTTTTCCAAGTTCACTACAGATATTGA AAGAGTTCCTATTCTTGTTTGTGGGGGACTGAGGGCCCTTTGTCTTTGCTGACTGTCAGC CAGGAGACACTCTGACTCCAGAGGCAACCTGCTTTCCTCCTTACCTGTCTTTTCCATCAT CAACCAATAACAACTCATGGAGTCCTTCTCAAGCTCCTGCCTTCTGTGGCTTCATCTTCT CCAACCAGCCACAGAAAGCTCTGTCATGTATGGAGTGGTGTGATTAGATCCAGTTCATGC AGGTAACCTCACCAGCTCAAAGTCATATAACTGGCATATAACATCATAATCACAGGAATG CTGTCTCATCACCTTAACAGGCTTTAGAGACAAGGGTGTGACATATGTGGGGACCATTTC AGAAATTCCATCTACCACAGTAGGACACTCACATTCCCCCAACTGCAAAATGCATTCACC GTCTCCCCTAAGGTTCCCAAATTTCATGTCATTTAAAGCATTAGTTCAACATGAAAAATG TCATGTAGATCACATCAGATCAAAAGTTTAAAATTCCATCTAAAACATCCACACCAGGTG TGGTGAGGCTTCTGAGGGTGTCCACAAAGTACAGGTCTTTGACATAATTCCCTTACCTCC GTCGACCTGTGAAACTGAACAAACAGCTTATCTGCCCCTAACGTGAAATGACGGGACAGA CATAGAATAACAGCTACAGTGATTCTAGTTCAAAATGAGGGAACATGGAAGGGATAAAGA AGTCAATGACCCAAAATAGTTTGGAAATGGAACTGGGCAAAATCCAGCAGAAGTTTCTTA ATTAGGATCGACAGCCTGGGACCGGCCCGCCGTCCTATGGGTCTTTGCCTCTGGGCTCCC TGCTCTGCATTTCTTGAAACCATTATTATTTATCTTTTTTCTCACACTCTTTTGCATATG GCTTCTGTTGCACTCAAAATGTTTTTGAGATTCATCCATGTTGTTTTATGTGTCAACAGT TTGTTCCTTTAGCCATTCCATGGAATGAATGTATCACAGTTTATTGGTCCATTCTTGTAT TGACAGATACTTGAATGTTTCCAGTTTTTCATATTATGAATAAAACTGCTATGAACATTC TTGTATAAATCATTTTCTGGACATATGTTTTAGTTTCTCTTGGATAAATGCTTAGGAATG ACTGAGTCATAGAATAGGCAGTTGTTTGGTTCTGTAAGAATATGCCAGATATTTTCCCCA AAGTGTTTATACTATTGTACATTCCATGCATTAATGTACGAAGATGAGAAAGCTTTTGCC CCTTCCAAAGAGGCCTGTCTATATACATGTAATTTTTTCTAACTGGAGACAGGCTGATGA CTTCAGGGACATGAACATGGGATACAGGACACCTGTCATCACCACCACCATGAAGTTGGG ATTCAGGAAGGAGGTTAATCATATAAGGAATCCTGTGACCAGCATGAGCTTCTGTCAGGC CACAAAGGGCACTCAAGTGAACAGGGCATAGTGGGTCCTGGGGTCATGGTGAGAAAGTGT CTCTTTGGTAAAACCTTTTCCCTTGGGGAGGTAAATAAATTCTTGGTTCCTTCTTGGTAG CCCTTGTAGATAAGGATGGTCAAATAAAATAATATTATATCTGTAAAAACTCAGATCTTG GTAAGATTTACTAGTTGGGAATCCAGTGTTAATGCCATGAAGCAGCCGCCAGTTGGGATC AAATGTGAGCCTATGGATCAAGGTGCATACTCAAACACAGAGAGCTTTTTTGAAAGATGC CACCAGTAGTTTTTCCAGGGCAGAGATGGGTCGTTTATTTCTCTCTCTAATCTAGCCCAT ATGCTAGCTGAGAAGGTTTCTTCATATCACTTTAAATGATGATGTCCTTGTACAACAATT TTCTAAACATTCTTTAGATAAGAATTTAATGGGCATTCTTTATTGCATTAGGCTTAAATT TCATGCATCTTAAGGTTTTATTGCAAAGTGTTGCCTTGCTTCCTTTTTAAGATGATACAA TTTATAACACGCAAGTTTGCTGTCTGTCCCCTCCCTTTATATACATATAAAATGAGCAAA CATGTGGCCATGAAACAGATGGTCATAGAATTGGTTCAGTGGTTGTGAGTTCAGCAACCC AAGAGTGTCTTATCTGAAATACCACGAGGAATGCCTGGACACAGTAGACAAAGGTTGTTC AACTGGATGCCTTAGGATACATGCTACCAAAAACAAAGTAGCTGAAAAGGAACCAGAATA ACAGAATATCAGAGCCAGAGGAACATTTGGAGGTAATTCAGTACCTCCTCCTTTTCAACC TACAGGGGAGATAGTGGAACAGAAGCAGAAATGGGCCTGCCTGCTGTGCCCAAAATTCAT TGGAGATTATTGCGGTGAAGAATTTCATTTATGATGAAGGAGAATTAAATCCCCGTCAGT TTAAATTCAGGCAGGTTTATTGAAAAGGTGAAGAAGCGTCTTGCAGAAGCAAAGCGTGGC TGAGGCTTGTGGGCTTTGGGAAAATGAGCAGCTGACAGTGGCTGATGCTGCCCCTGACTC TGGGACCATGTGGTCTCTTGTTCCCTGAGAGCATCTCTTCTATTCTCTTGCATCTTCCCT CAGCCTGGCAGTCTCTGTATAATCTTCAACACATAATCGAGCAAGGCTGTGCCAGCCCCA ATGCCACCTGGCACTTTAGGTCAAATTAGGAAGGCATGAAATAAACTGGCCCTTTATAAT ACAGCTGTTGGAACCACAGTTGAAAGTACAATATCTTGACTCCTGGGTTAGTGCTTTATG CTGAGCTTTTTTTTCTGAATATGAGCACAGACTTTGGAATATTAGTGTCACCTAGCGTTA TTAGCTAGTATTCTCCTTTTGTTTCCCCATGACATCCCCTCCTTCTTCCCACAGATCCAC TGTCCGCTCATTTCCATCCTGTCTCATGCCACTCGGGGCTCGTCCCTTCTAGAATGCATT CCTGGCTCCCCTGCATGCACACTTCCAGTTAGGTTTAGCAATGGAGGGCACCTGATGGAG CCTGGAAGTGAGAGGAAGGTGAGGTCTGTATTTCTTCCCTCTCCCTCCCTGCTCTGGCAC TGAGTATCTGGCAATAGCTGCATCTGTCTATTACTTCAGTGGCCACTCTTCCACAGCCCC AGTTCTCAGTGGGTCCCATAGCATTATTTACCTTTGTTCCTTTAGCTCCCATCAAGGAAG ATCCAGAGACATTCTCCTTACCAAGACGTTAAGAAATGCACAGGTGAGGAGAACAGCGGC ATGCGTGTAAAGGTCCTGTGGCACCCATCCTCTGCAGGCTGGAGGTCATGGCGGGAGATG CTGCATGGATTTGCCCTCCCCGCTGTCAGTGAGAACAACAGGGTTCTGGAAGAGTAGAGG ACAGGCCATGGGACTTGGCCATCTAGAGATAAGGCGGGAGGGATTTCCTTGAGAGGCAGG GATATGTGGTGGTTACTAATCATTCGAATCATTGTGAGGTGTCTGGGAATGTAATGGATG GGAAATCTACTAAGAAATCAACTTAGTAATAATTAGAAAAGCTCTAGTTCTGAGGACAGA GACCTGATGGAGTCACCATAGTGGGAATTTATGACCTGGCATCCGGTTCAGATACCTGGA GCTTCTTGAGTGAGGGAAGATTGGATCCCTTGAGGAAGAGTGAAGCCTTCAATGCTGCCA CCAGTGTATGCTGTAAATCTTCCTCCAGGCCTTCCCCAGAAGGCCCTGAAGCCATTTATG TGGGTGACTGAGGAAAGGGAAATACTCAGAGCTTCTGTGGCTTGTTGGATTCTGGCTCTG AAGAATGCTAAACTAAGGGCACCTGTGGTGGCCATGAAAATGCACTACTTGCATCTCCAG CTGCAGGAGGCCTAACGAATCAGCAGCCCCAGCTGCTACACTCCGAATGGAGGACTTGAT GACATTTCCCCTGGATCTGCACTAGCCCATGAGGAGGAAAGCCTCCTATCAAGTCCTCCC AGCAGAACACCCATGATGACTCATGAGGATGTTGAAAGTGTTTTCCTGTGTCAACTGTGA CTTTCTTTCTTCAAAGTCTGTTTTGTTCCTGCACATTAACTGATTTATATCAAATAAGAG AATAAATGCCTAGACTCCCATGAGTCTATCTTTTACTGATAAACTCAATAGTTCTGAGGA CGGAAGCCTGATGGAGTCAGTATAGGGGGAATTTATAACCTGGCATCCAGTTCAGAGACT TGGAGCTTCTTGACTGAGGGGAGATCGGGTCCCTTTGGGGAAGAAGGAAGCCTTCAATGT TGTCACAAGTGTATCCTGGAAATCTTCCTCTAAGCCTTCCTAGAGAGACCTGATAATATG ACTTATGATACAGTGACCCCAAATTCAGGGTGTTCTTGTCTACTCTCAAGAATGCAATAT CTTCTTCCTCTGAATTGAACGTAGTACCAATATTTGTGTGTAGCTATGCACCTTAATAGA CCATAGCTAATTAGATGAGGAATGGTAGACCCAATTCAACCATACAGGCGTCAACCATAT CAGCATACAGGCATCCCTCTCCCACCGTTTCCTTCTTGTCCCCACTCCAAAGCCTTCTCC ATTTTATTTGTATTAACTTTCTATTGCTGCATACTAAATTACTGCAAGCATTAGCGGCGT AAAATAAGAATGATTTATTTTCTTGCAGTGTCCACAGATCAGAAGTTCAGGCCTGGATTC GCTGGGTCTTCTTCTCAGGGCCTCACAGGCTGAAATTAGGCTGGGTTTCTTTCTGGAGGT TCTGGGGAAGAACATCCTCTCAAGTTTCCTCAGGTTGTCAGCTGAGTTCAGTTCCTTGTG ACTGTAGGACTGAGATCTCTGTTTTCTTGCTGGCTGTCAGCCAGGGGCCTCTCGCTGCTC CTAGAGGCCTCCCATGTTCCCACTGCATGCTTCCTCCAGCCAGCAGAGGAGGATCGCCCT GCATGGAAACCCTCCTGCACTTCACATCTCTCCAGGAAGTCCTCAGTCCCTCCAAGGAAC TCACCTTCACTAGGTCAAGCTCATCAGATAATCTGTCTATCTTAAATTTGACCGATTTGG GATCTCGATTACATCTGTTAACTTGTTTTTGCCATAAATTGTAACACAATCGCAGGAGTG ACATCTCCTCAGTGGCTTTGTCTACACTCAGGAAGAAGTGATTATATAAGAGCAAAGATC ACTGAGGGTCATCTTAGGATTCTGTCTACCATAATATTATAAAGACACAGTAATTAAAAG AGTATAACAGATTTCTGCTTCTGTCTGTTAGAATAAATCATATCAGACTAACCCTGCCTC CATAAACAACCGTAAAATTGTTTTCAGCAGTGTACGACAGGCAGTACAACAGAAAACTTA AGGGGGAAGCCCCATGATTTCCTAGTTCTTTGGGGAGAATTTCTCAGCAGCTGCATAGTG GGCTAGAGTCCACTCAGGGCAGGGCAGCCCACTGAGCTGAGAAGGCAGAGATCAGAGTTC AAGACCATTGAAGCAACTGCAATCTGCAGGGCAGGGCACCAATGAGGAGACAGCTGATCA AAGGTGCAGCTCTCAAAGTCTATGTGGGGTTCCATATGCATCCTTATCAAGGACTGGACT GTACCTGCACAAGGAAAAGACTAACAGATTTAACAGAGGGGTGGCTGCTATAAAATTGAG TTTGGACCAGAGGTACTTGAGGCGGAGGAGGGTTGGGGAATGTATGATGGAGTTTCTGCC ATCCACGGTGGGAAGAACTCATGCACACCTCATTAGCACCCAGGTATCCAACTGAGACAC TAGAATGGATGTGCTTTAGGAATAAGTGTCACACTTTTCAATAAGGCCTATTGTTCACCA ACCTGGTAAAGCCTAAAGCCAAACCCTGACAAAATCCACAAAGGGGTGGATTGGTGATTG AGTCCTGCCAAATTAGAGGGTCTTGGGAAATTCTGTGGGCTTTCCATGAATCCGTTGTAA TAAAACATAAACCAGTCCACATAAGTCCAAAGTGATCGATCAGACAGTAATTTTACGCCC ACTAGAGCAAAATTAATTCACACAATCAATGACACAAGTTAGCCAAGTCGACATTTAAGC AAAATACATCTAAGAACAGCTAACAAATAACTCTCCTCAAACTCACATAGAGCATTCACC AAGATAGACCACATATGCTGAGCCATCCTTAGTATTTTCTGTCCTTTCTCTTTGACTCGT GTATACTGTGCTCAAACTCTTAAAATTATACACTTTAATTATATACTTTAATGATTATAC ACTTTCATGCATCTCAATTGCATGTAAGTTATATTTCAATATATTTGTTAAAAGTTTATA ATTAAAAAAACTGTCCTAGCTTGATTCCAGAAATCTTTTTTATATTTTAGAAAATGTAAT GTTATATATTATCAGGGCAAAAGAGAAAAACCGTATGATTACCTTGTCATACACAGTAAA AGCATTTGGCAAAATTGAAAAATTTTTCATGATTTATAAAAACAAACCCCAGAAAACTCA GCATGATAAGAAGAGAAGGCAACACTTCCAACCCTATTAAGGGTAGATTTGAAAAAAACT CACAGGTAACATTATATTAAATGGCATGGGATTGAATGCTTTTCTATTAAATCAGATAAA AAAGTAGAATATCTGTTGTTATTCTTTCAATTCAGCATTATACTAGAGATCTAAATCAGT GCAATAAAGTAAGAAAAATAAAAGTATTGAAAAGATTGAAAAGAAAGAATTGAGGCTGTC TTTATTCACAGATAATGACTGTGTATGTTAATAATCCTAGAAATCTGCAAAAATCTGCCA AAGCTAATTAGTGAGTTTGGTAATGTTGCAGAGTATAAGCTCAATAGAAGTAGTCTTTTG TATTTCTGTGTATTAGCAATGAGCATTTGGAAAATGAAATAAAAATACAATTTCATTTCA AGTAACTTCTAAATACATGTGCTTATAAATAAATTCAACAGGCTGGGTCTGGTGGCTCAC GTGTGTGTGTGTGTGTGTGTGTATGTATGTGTGTGGGTGGGTGTGGGTGTGTATATTCAC CTTTTTGAAGATTATCTATCGTTATCTCCAAACAGGGAACATTAAGAGAACATAAAAAGA AACCACAATATAGGAGATATCATATTTATTTCCAACAAAGGGTTTTTAGAGTGTGTGTGT GTATATATATATATATGTATGTATATATATGTATGTATATATATGTATGTATATATATGC ATGTGTATATATATGTGTGTTTATATATGTCTAATAAGAAACAACACAATGAAACAATTT CTCAAAAGACTTGAATAGATACTTCAGTAAAGAAGATACATAAATGGTCAATTAGCATAG GAAAAGATGCTCTACTGTTTAGTCATCAGGGAGATCAATGAATACAACTTGATAGCAGTA CATATCCAAGAGGATGGCTAAAATTAAAAAGGCTGAAAATAGCACATGTTGGTGAGGATA TAAAGCACTTGGAAGTCTTATACTTGGAATGAAAAATGGTAGGACTCCTTTGAAAATCTA ACAATGTCTTAAAGGTTAAACATATGCAAATCAGATGGACAGTCTTCCATTCCTAGGAAT GTACACACTATGTGTGCACATGATCTGTATGTGTATTTCCAGACCAGACTGAGGGGTGGA CTGCTATTTCTTGTGGCCCAGTAACGAGATGCAGATGAACTGGGGAGGAAGAGAGTTTTT ACTTCTGCAACTGATTACAGGGAAAAGGCCTGGAAATTATCACCAGACCAAGTCAAAATT ACAAAGTTTTCCTGAGCTTATATACCTTCTAAGCTATATGTGTATGTGGAAGTGTGCATT CATCTAAATACAGAAGTGATTAAGTTCTTCTAATCTATAACTAAGGTCTGAGTCCTGAAG ACCTTCCTCTGGAGCCTCAGTAAATTCACTTAATCTAAATGGGTCTAGGTGCTGGGCACC CTTATCTTGTCTCCTGCTAAATCACAGAGGTTTGGGGAGTTCCTTCAGACCTCCAATAAA CTTGTTTGTGGAGGCCTGGGGAGTTTCTTCAGACCCCCAATAAAACTTGTTTAATACTAA ATGACTCCTGTTAAGAATGTCTTCGTTATTTTGTCATGCTTTAAGGCCCAGGAAAAGCCC AGGCAAAGCTCTTGGTGGGCTTTGGTTACATTCCAGCCTTTGTAATAAGGGCATGGGCTT TTTTTTTTTTTTTTTCCTCTTAATATTTAACTGAACCACTCAGTCGGTACTGAAACAGTT GTTAGGGAGGCCTGTGTTAGTGAGACCTGGCCTGCCACGTATGGATGCTCATGATAGTTT CTTCATAATAGCCCAAACGTGGAATGATAGAAATGTCCAATAACAAGTGAAAGTATGAAC AAACACAGTATAGCCACACAAAGGAATACTACTCAGCAATTACAAGGCATTAACCGTTGA TGCAAATACTCATATGGATGGATTTTAAAATTATGTTGATGCATGAAAGAAGGCAGACAC AAAAGAATACGGGTACAATTTCATTTATAGAAAATGGTTAAAAATGGAAACAGACCTGAA GTGACAGCGGCTCCTTGAGGCCGAGGGCTGAAAGACTGATGAACTGCAAAGGGGTACAAG AAACTTTGGGGCGTAGGGAAATTCCTCTATCTTGGTTGTGGCAGTAGTTCCATTAGTGTA TACATTTGTAAACATGCATTGAATTACACATTTTAAAGTGGTGCAGTCTGTTGTACCTAA ATGATGCCTTTATAACATTGATTTCATCATCTTAATTTCTCCATACTAGCAATTAGCAGC TAGAAAATGAAATTCAGTAAAACATAATCGAGATTAATAGTCAGAATCATTACATGCTTA AGAATACATGCAATGAAGCGGGTACAAGGCCCGTAAAAGCAATTGGTGAGAAAAATTAAA GAAGACTAAATAGAGAAATATATATCATGTTCATTGATTGGAAGATTCAATTTTGTTAGC ATATTACCTCAACAGAATTCTGATTAATATTTCTAGTAGGAGATTTTAGAGAAATGTAAA AGCTAATTTCAAAATATATTTGAAAATCCAAGAACCTAGAATAGGCAAGTCGGTCTTGAA GAAGCAGTAAGTTGGAGGACTTACTCTGCTAGACTTCAAACCTGATTTAAAAGCTACAGT AATTTAAAATGGTAGTACTGGTGTAAGTATTCATAAATATATCAAAGTAAAAGAATACAG ATTCAAACAATATGACCACATATGTAGTTATTTATTTTAGTAGAATCTTTTTTATTCATA AAAAATCCCTCCAAAACGTTTTCCAAGAACACACAGGAGGGCTATGGGTAGAGGAAGGTG TCTGTCCATCTATCCCTGGCCCCCAGCCCATGTGGTTTTGGCAGCAATAGGGGTGTGGGG TAATGTCCCCCAAAATTAAAATGGTATATGTGTGTATGAGAAGGAAAGGGGGGCAAAGCT GTGGGGAACGGTTGAGGGGAAGGAACAAAGGAGGTCAGTACTGGGAACGCTGAAGATGGG AGGCCATTTCATAACATTTCTTGTTGATGAAACTGCCATGGACAGCTTCTTTGCTCATCA GCAGGCCCAGTGTCTTGGCAATCATGGTGACAGTGACATTGAAGGTGGGGGCTCCACCGA TGCTCTTCGTTTGAAGATGCACGGTCAGTTCCCCATCCTGCAGCAGTGAGTCCAGGACCA CAGTACATTTCTGGCCCCGCAGTGTCAGCCTATTCACGAAAAAGCTTGACCAGTCTTTGC CAACCAGGACACCAACCTTAGCTGGCGTGATGTTCACGAAGGTTTTTCCCTGGGACGGCG GCCCAGATGGAGGGTGAGTCCTTGTTGCCCACGATGGCCGCGAACCTAACAGGTCCCATC CGCCACGAGGCTGTAGATAGAGGCGTCCACCTGGCCGTTGCGCGGCTGCGGGGGCTCCTC TGGTCGCTGCTGCTGGGGCCGCCTGGGCTGGCGGGCAGGGGAGGCGGAGAGCTGCGTGCA GGCACTGCCGTCCTCACCACGGCTCTGCTGGCTGTGCAGTGGCCCTCGCACCGCCATATA TATATATTTATTATACTTTAAGTTCTAGGATACTTGTGCACAACGTGCAGGTTTGTTACA TAGGTGTACATGTGCCATGTTGGTTTGCTGCACCCATTAACTCGTCATTTACATTCGGTA TTTCTCCTAATGCTATCCCTCCTCCAGCCCCCAACCCCAGGGACAGGCCGTGGTGTGTGA TGTTCCCCGCCCTGTGTCCAAGTGTTCTCATTGTTCAGTTCCCATCCATGAGTGAGAACG TGCTCACGCTGCTACTTCTAAATGTTTTAAAAACAAAGACACCAATGCTCTTCATTGAGG AAATGGAAGACTTTTAAGTAAAAGGATTTTGAGTGAAATAATATTTGTGGTTTTAAAAAG TTAATATTAACCACTCTTCATCATACACTGAAATTAACTTAAGATGTGAAAGTTAAAATT AGAAACCTTGTAAAGGAAAAATAGGAACTAATTTCGTGGACTTGACACAGGAAAATGTTT CTTAGACTAGATACTGTAACACTCACCACAATAAGAAATCAAGCAAATTGCCCTTCATTT TTAAAAACCTTCTGCTTATTATGTTGTTGTTTAACAACTTAAAAGCTATCTGTAGACCAG GAATAGCAAATAATTATTTGCTATATAATATAGCAAAAAATGTGTATATATAAATGGATG CATTCAAAATATATAAAGAACTCCTATAGGTTACAAGAAAATGACAAACACACCAGTGTT TCAATGAACATAAAATTTTGAGAAGATATTTTCCATAAGAAGATATCTTACTGAACATTA GGCATGAGAAAACCAAAACAGGATATCACTACCCACCTAGTAGAATGGCTATAATTTAAA AGACTGAAAATATTAAGTGTGTGGGAATGTAGAGCAACTGGAAATGGCCTACATCTTTCA TAGAAATGTAAAATAATACAATGACTTTGCAAAGCTCTGTGTCCATTTTCTTCCCATTCA CCAAGCAACTCCATCCGTAGCTATAGAGACCCAGGAAAATCAGTATGTCCATTCACAGAA ATAATTATATGAGAATATTCATAGTTACTTACGCACAGTAGCCAACAAGTAAACCTGTCT CCCGTCAGAAAAATGGATATCAAATTGTGTGATAATCATACAAACAATAGGATATTACTT GGCCAAACAAAACGAAACAAGGGAAAAACACAGTCAAACAAATTAGTGGCATATATAAGC ACCTGAGTAGGAGAAGTCAAAACAAGAGGAAGTACTAAATGATTCCTTTTTTTAATTTTT TTGAGATGGAGTCTCACTCTGTCCCCCAGTCTGGAGTGCAGTGGCACGATCTCGGCTCTG CCTCCCAGGTTCAAAAAATTTTCCCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCA CCTGCCACCATGCCTGGCTAATTTTTTGTATTTTCAGTAGAGGCAGGGTTTTACCATGTT GGCCAGGCTGGTCTTGAACGCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTTGCAAAGT CTTGGGATTACAGGCATGAGCCACCAGGCCCAGCCAAAATGATTCCATGTTTATGAAGCA CATGATCAAGCAAAATGAATCTATGGTGGCTGCTAAGTTTAAATATTGGTCCCCTCCAAA TCACATGTTTAAATGTGGTCCCCAGTGTCGGAGGTGGGGGTAAATGGGAGGTGTTTGGGT CATGGGAGTGGATCCCTCATGAATAGATGAATCCCCACCCTGGGAGAAGGTAGTGAGTGA ATTCTCACTCTCTTAGTTCCTGTAGGAGCTGGTTATTAAAAAGTGCCTCTCACCTTTCCT TGCTCTCTTTTGCTTCCTCTCTCGCCATATGATCTCTGCACACCCTGGTTCCTTTTCACC TTCTGCTGCAAGTGGAAGCAGCCTCAGGCCCTCATTAGGAGCAGATGCGGGGGCCATGCT TCTTGTACAGCCTGCAGAACTATGAGCAAAAGGCACCTCTTGTCTTGATAAATTACGCAG CCGCCGGTATTCCTTTCCAGCAACACAAAGGGGCTAAGGCGGTGACAACATTCAGAATAT ATTCTTCATTTGGGGAATGAGTATTGACTGGCAAGGACCACATCAGAACTCTGTGGCATG GGGGAAAATGTTCTCTGTCTTTAACTGGGTGTTACTTTACAATTATAATTATATTAAAAT TTATTAAGCTGTGCCTTTAGGTTTTTTGCAGTATACTCTATGCAAATTTTACCTCAGTGA AGAACTGTTAGCATACAACAGAGAGATAACAAACACTCAAAAATTGAAAATTGATGGAAA GTAGATAACAAATATTTAGCCTAGAAATAAGAGGGATCCATTGAGAAGAAACCAAAAGCA ATGGAATAGAACAAAGACAAAAAAGTATAATAAAAAGAGTTTTAAATTTCAAAGTTTGAA ATGATATTCAAGTGACACACTGTTTCCTTGGGAAAATCAAGTGAGAACCACAACTCTGAG ACTAATTCCAGCAAAAATATGTGAATCAGTTTGATCTAATGGTACAAGGTTAGCTTTGAA GGCCAAAAGGAACTGGTTTCTAATTCTTATTCCTCTCCTCACTAGTTTTGTGACCTAGGG AAATTTTGCAATCTTTCTGAGTTTGTTTTCTCATCAGGAACAGGATACTACCTAAGTAAC AGGATAGTTGATAGATTTAAATATGATCGCATGGCAGTGGACATGAGCCATAATTAGTTG CTAAGAATATATTGACACTGAACTCTCCTTTATCCATGTTAAAATTGTAGATAAACAACA ATTGACAAAGAATAGACAAAATATTCTAACATAAATATTCTTCCCTTGTTTCTAGAAAGA AGTCACACATACAGTAAAAATAATTAGAGAGGACCTAGTTCATATTGAGCAATCTTCCCC AAACCCTGAAACAGGTCTTCTTTCTAACACCAGAGGTATCTTGAGTGAGTCCAACCCCTG CAGTCCCCTCTGTCTGGAATAGATGGAGGAAGTTTGCTCCAGCCTTAGAACAGCATGGGC TGGCAAGCGTTCTCAGAGAGGTCTCGACTTCAACTCTAAAGGGCCTGAGGAATATGTGCA ACTGGGTCGGGTTAAGGCCAAGCTGAATCACATGACCAGGGCTCTCACCAGCGCCAAAGT CAGTGGAAGGATATCAGTCCCCAGAGCTCTGTCACAGGCCATGGATGCTCCATGGAGGGG TGGTGAGCATATGAATAAGAATCAGGAGAAACATCGGTAATGGACAGGAGGCATAAATAA ACAATGTCCACCGTCCTCTAAAACCCAGGAAAGTTCTCATTCAAAAGACGATGTCTTGAA GGAAACATAGGTACAAATCTTTGTGACTTTGGATTAGACATTTTTTAAGTAGGCACAAAC AACCGAAAAATAGATAAATGGACTTCATTAAAATAAAAAACTTATATGCTTCAAAGGACA CTGTCAAGGAAGTGAAAAGATAATCCACATAATGGGAGAACTATTTCCAAATTATATGTT TGACACAGGTCTAGTACCTAGAGTATATAAGGAATTCATATAACTGAGCAATAAACGACA ACCACATTTAACAATGGGGAAAAAAGCTGTGAGTAGAGGTTTCTCTAAAGGAAACACTCA AATGGCCAAGAAGCACATGCAAAGATGTTCAATGTTTTTCGTCATTAGGAAAATGTAAAT TTAAACCAAAATGAGATACCACTTCACACCCAGCAGTATGACTTAAGAAAAAAATAAAGA CAACACATGTTTCAAAAGTGATGGAGAATATCGAATTCTCATATATTACTATTGGGAATC TAAAATGATGTAGCTACTGAAGTTAGTAAACAGTGTGTGAGTTCCTCAAAAAGTTAAACA TAAAAAAAGTTAAACATAAAGTGACATATGATGCAGCAATTGCACTCCTAGGTTTATAAC CAAGAAAATGAAAAACAGGTGTTCACTCAAAAACCTGTACAAAGCTGTTCACAGCAGCAT TATTCATAATAGTTAAAAAGTGGAAACATCTTTAACCACCATCAGTTGATGAATAAACAA AATGTGGTATAACCATATAGTGGAATATTATCTGGCCATAAAAAGTTGAAGTACTGATGC AGGCTAGAAAGGATGAAACTTGAGAACAATATTCTAAGAAGCAGATAGAAAATACCACAC TTTGTTATTCCATATAGAGGAAGTGCCCAGAACAAGTACATCAATATATAGAGAAGGTAG ATTAGTGGTTGTCAGAGAGCACAAGAGGGGGGGAATTGGAGAGTGTCTGCCCATAGGTAC AGGCATGCTTTTTGGCATTATGAAAATATTCTGGAATTAGGTAGTGGCGATGGTTGTGAA AGTTTTGGAATATGGTAAAAGACACTGAAATGTATGCTTAAAAATGGTGAATTTTGTGAT GTATAAATTCTACTGTAGAAATAATAATAACAACAAAAGTAATAAAGCAAGGTGTCTTTC CACATCTCCATGTCCAGTATTTTCATTAAAAAAAAAAAAGAAAGTAAAAGCATTTCAGGG CCAGGTTCAGTGGCTAACTTCTGTAATCCCAGCACTTTTGGAGAACTAGGTGGAAGGATC GCTTGAGGCCAGAAGTTCAAAACCAGCCTGAGCAACATAGCAAGACCTTGTCTCTATGAA AAATAAAAAATTAGCCAGAAATGGTGATGTGTGCCTAGAGTTCCAACTACTTGGAAAGCT GAGGCAGGAGGATCGCTTGAGCCCAGAAGTTCAAGGTTGCCGTGATCTATAATCACCAGT GCACTCCAGCCTGGGTGACAGAATAAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAA AGCATCTCACTTTAATAGTAAGTGGCCAAAATATGATGCTGGCTGCATGTTGTGAGGAAA TGTGTTAGATGAAAGAAGTTAAATTCCAGAAGATTTCCTTTTTTCAGAAATGAGGTATAG GGGAGAGAAGCACTGGTCCACCTGAGATCTGGCTCCAGGACTTACAACAAGGGGAACTTG GGCAAGTTACAGACTCTGTGTGCCTCCATTTCTTCATCAGCAAAACAGAAAGAATCATCC CATAAACTGTAAGGTCAATGCTGTCAGTGAGTCCCCAAATTGACTGCACATCTGAGTCAT ATTAACAAACACATTCCAGGCCCCACCTGAGCCCTCTGAATCAGAATCCCTGCAAGGAGG ACAATGAACTTGTATTTGCACTGACTTTCCCAGCTGTTTCTTACTTTGATCAACTTGGGG GTGGGACCCATTGAGCTGCATCACATCATTCCAAAGCCAAAACACAACAGCAGAACAAGA ATATTTTCAATGCAGTCTCTGAAGCAGAGGAGAAACTTTTGAGGGAACCTAGAAGTAAAG GACATCTGGCTTGCTGGGCTCCATTTAAACTTTGAGTATAGCAGAGACACGAGCCCTTCG GGACACATGCCTGTCGCAGTGACACTCCAACTTCGGAAGAGTGGAAGCCCTAATTCCAAA TTCAAGCATGCTTTGAGTAGAAATGAAGTTTGCCTCTTTTTGCACAGGAAGATGGCCAAT CTTTCCTAAGCTGCTGACCTTACAAGAAAAAGAATCGTACTGCTAAGAATTCAAACTTCA GCAGTCATGGGTGAGTAAGGAAGTCTTATAAATGTATTTTAGCCACCTAACAAGAAACTA GAAATTTAGCAAGTTCTTTCACATTCAGGACAGTTGTGTTCACTAGATCAGAGGCACTGA GACATGAAGAACAGACCCCTAAAAAGGGAAAGTGTTCCTTTCAGTTTTAGGACACCACTG GAATATTAGGGAAGTGGAAACACAGCTGCCCACTCTACAGTATGGGTTGCCTTTGTGTCC GGAATGTGCCTAACGTCCTGACCTCCATGCCCTTTTCAGGGAGCCTTGGGAGGAGCCCGA ATCACTGATGGAATCGGACAGTGCATGGAGATGGTTCAGCAGGACGAGGGTAAGTGCAGG GGCAAGTCCAGGTCATACTGAGAGACAACGAGTGGCGCTGACAAGAGACAGACAAAGATA AAATCAAAAGTTTGTGCTTCATCTTCAAAAATCCAAACTAATAACACACTTGGCCTTATG AGAAATAATAAGTATTTTTCTATTTACATGAGAATTTAATCTCAAAACAGGAATCAGAAA TATATTAAGTCCAGGGCATAAAACCTAAACCACTGCTCATATTTATTCTTTCTAAATAGA GCAAAGTGTAAAATCTTCTCCATAAAATGCACATTGTGCTTATGAAAAGGCCAAAGTCTT AGTGAGAATCATTGGTATTCCATAGAAGAGTGAATTAAACACAGCCAAGGGAAGACCCAA GTCTCATACTTCTCTTGTATATTCCAGAGTTCCAGGGGAATTCCAGGTGATAGAGGTGAT CTCCCATACTGTTAAAGCAAGGTTGCAGACACTTGGGAATTTTGGTCCCAGTACTCTAGG AGGTCACACCTCTGTCCTGGACAATACTACAGGAATGTATACTCTTCCTATGACTCATTC TGGTCATTCTTCCAGCATCACAAAAACCAAAAAAAAAAAGGAAATATGTCCAAATACATG ATTTGCTATCCCTCCTCTTCAAGTTTCTTACCTGTTACTTACGGATAATAGCATTACCAC AGGATTATGATGAAGATACAATGTCCAAATGTAAGCACAGTTTTGAGCAAAATGCCTTGT ACGAATTGGTCAGTGAACAACTGGTAAATAATTATGTGAATATTTACTGAATTATATGGA TCCTATGAATAATTACTGAATAATTACTGTGATTGCTTTTATTGGCAGTGCTGAAAACTC ACCCCTGTGTGACCTCAAGTAAGCCACGTAACTCTGTGAACCTGCAGTTTTATCATTTTT AAAATAAAGAAACATGACAGATTTTCATTATGACACAGAATGTCAGGTCTCCCAGATGCC AGAAAATACATTTACTTAAAGCCGTTGATACGTCTTAAAGCGGTTTCCTTACAGTGTCAT TGGAGGACAGCGTGGAGTGCAGAGAGACATGCTTTGAAATGGGATTGATCCAGTCCTCCT TCCTTCACTACCACATGAATGCTGGGCAGCCCAGGATCACACTCACTGCACCCTCAACTC AGGCAAGTCCAGCAGCCAATCTTAGGAGACCTGGGCTACAGAACAGTCTCCCAAGTTCCA GGCTCACAAAACCTAGGTGGGGATGAAAGCTGAGAAAGTGAGGAGGTGGTTCAGGGGATC ACTCTTTCCTACTCATTCCTCTCATCTCAAACTCACCCTCTACTGCAACACTGAGGATCA CCAACCAACCGTGACCATAACCTTGATCTTGCCATGTTCTGTTAGTGGAATGAAACCAAA AATCAATGGTGTTAGTCCAACCCAACGAAATAGATATCAAACCACATTCCATAAGAACCG CCGCTCATGGCCCTGTTCTTTTCAGTATATGGGAAAACAAAATGGAAACAACAAAATAGC ATCAGGTTTATGAAACTTCCCAAGATAGATGGTCACACATGTGTTCAGGAGATCTCTATA TAAATGATTTTGGTCACTTGATACCTTGAAAAGAGCTCTTGTGATACTAGAATGACATCC ATAAGTGACGAGTATAAAATGTAGCGCTCAGTGACATCAAAAACCAAATCAACCCACATA GAGGAAGAGCTCTGGACATAGGGATGTCAAACTGGTCTAGAGTGTAATGAAAAGCAAAGA TGGTGCCCCAGTGAGAAAAAAGAAATCAACGTAACAATGGGAATCAGCAAGAAGAATACT GAGACAGGAAAGACAACATTTTTTACAAATGAGTTATTCATTCACTTTCTAGTGGATACA GACAAAACTGCAGAAGACCCAGAGGAAATCAGGGCAGGCTAAAAGTTTGATATCTTACAC TTGTGGAAAAGCCTTAAGATCTGTTTTAACTGAGAGCAGGTGGGGTGACTTCATGACTAC CGTTAAGAAAATATAACCTGTTGGGAAACTGGTTCTGCCTGGATGGTGTTGTACAAACAA GCGATAAACAATGAGGAATGTGCTTAGATGTATTGGGAAAGAGATGGGTCTGTGGCATTG TCACAAGGGTACACGAACACTGAGAGTGAATTTTAGAGGAATGATCCCCATTGGTGGTGA CCCTCAGGTGAGACGAGGGTGCCTGTGTTTCAGCAAAGCCTGGGCAATTGGAATGCAGGG CTCCTAAGATTCCATGACACCCCCACCTTCTAATTCTGTTATTGCAACTGCAGACCGTTA CCTGGCACACTGGCCTCACTCTTGTCGGAGACTGAGCTATTGGCAGTGCCTTCAGCTCTG AGCTCAGGCACCTCGAACATTGTTTTTGTCGTTAAGGATCCTAAAGTGCTGCGGGGACTG ATCACATTTTTCTCAACAGTAAGTTAAGAATTTCAGTTACTGACATCCCTCAGTCCTGAT TAAACCTATTTGATTTCACCAGTTTTTAACCCATCGTGTGTTTGGGTGTCTTCTCCCCAG TCCCTGGCCCCACCTCTTCTGCCACAAACGTCAGCATGGTGGTATCTGCCGGCCCTTGGT CCGGTGAGAAGGCAGAGATGAACATTCTAGAAATCAACAAGAAATCGCGCCCCCAGCTGG CAGAGAACAAACAGCAGTTCAGAAACCTCAAACAGAAATGTCTTGTAACTCAAGTGGCCT ACTTCCTGGCCAACCGGCAAAATAATTACGGTAAGTTCTATAGGCTCACCATCACAAAAG CGATGAATGATGTCCTGTCTTCTCGCTGAGAAACTAAATGCTCTCTCCATCAAAAATAAG TTCAACCCTCCCATACTTCTAGGAAAATAGAAATGGGCATTTTCACATTTTGTTAAATTG GGAAGTCAGAGGTACCAAAGTATTTAGCAACTTTCCATGTTTGCAGTCAGGTGGGGGTGG GCCTAGAGTTAAAATCGCAGTTATTCATTTGGGACACAGGCACAGAACGACCTGTTTTCT CCAAGAGGCTAAATCGTGTTTTCAAGAATCCTCTCTGTACCATATAAGATCCGGCAGACA AATAACATCTAGTCTGTTGTTCTAAATGTGTGGGACTAGTGAACCCTTATTGTGTTCAAG CTTCTGTTGAGGCCCAATAGGCAAAGCTCTGTTCTGGGGACCCTGAGGAAAACTTGGTGA TAGTACACAGTACCCGCTCTGAGGGGCTTCAAGGGGAGTCTGCTCCTAATAGAACCTGTG GTATCTGTAAGTGACAGCATCAAGAGCAGGGAGTAGGGGCCGTGCACGGTGGCTCACTCC TGTAATCCAAGCACTTTGGGAGGCTGAGGCGGGTAGAGCACGAGGTCAGGAGTTTGAGAC CAGCCTGGGCAACGTGGAGAAACCCCATCTCTTCTAAAAATACAAACATTAGCTGGGCGT GGTGGCGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCCCTTGCAT CCAGGAGGCAGAGGTTGCAGTGAGCCAAGAACACGCCATTGCACTCCAGCCTGGGCGATA GGGCAAGACTCGTCAAAAGAAAAGCAGAGAGTACCCGGTGAGAGGGAAGTCCTGCTTCCT GGGGCACAGGCTCTTGTTCCTAAAGAGGAAGAAGGATCGCACCCGAGATTGTGTGGAAGT AGCAGTGCAGTGTGCAGACCAGGGACTCTGGGCCTGTCTCCTGGGCTCCATCCAAGTTGC TTGTCTTGTCTGTCCCTCAGTTTCCTCATCTGTACATAGGGTACTACAGAAATACCTACC TCTGTAAATTGCTGCAATGAGTTACATGAGCTGTTTCTTGTCAATCTCCTAGAACTTTTA TTGGCACAGAGTTAACACTCTGTTAGTTCTTCATTCTACTGTTTCTAAATTAACACAAAC CTTAGTATTCGGGCAGATTTCCTTCATGGCCTTATGGTCTTACGTCTCATCCTTTATGCT TCAGATGTGATTCTTAAAATCACATCTAAAGCTATGATGTAAAAATCAAAGATGTTTAAG ATCTTTGACATATTTGTCCTTGAACTTCCCAGTGAAAGGGAAACCATCAGTCCCATAGTC CTAGGGGCCTTCCCAACTGTACAAGAAATCACTACTTCATGCCCCAGTGCAGTGCTTTAG AGGAGAGGCTGCAAGGCTTGGGAAAGTGGCCCCGCATTCAGAGTCAGACCTCAGGGGCTG TGAATTCTGACTCCACTTCATTGTGGTTGAATCATCTTGTCAACTTCCTTGATGTGCCTT GAGTTTCTCTTCGTCTCTAAATTTTGGAGGATCAGCTGCCAGTAAGTCGGGAGACTGAAG AGTAAAGATGTGGAAATCCCTACGTAGAGCCTGGCAGTGGGGACAGTTTTGTCCTTGGGA TGGACCTGGCTCCTGCCCTGTAGGCAGTGACCAGAGCAGCATGTCCAGCCTTTCACTGAG GCAGGCGTGTGTGTCTTTTCTCAGACTATGAAGACTGCAAAGACCTCATAAAATCTATGC TGAGGGATGAGCGGCTGCTCACAGAAGAGAAGCTTGCAGAGGAGCTCGGGCAAGCTGAGG AGCTCAGGTGAGTGGGCCCCCTGGGGTCAGGCAGGTGGGCAGGTGTGTAAATATCTGAAG TACAGCAGCTCGGCAGGGAGAACTAAGAGCTGAACTGGGCCAGGGGAAGGGCAGGAATTG CCATGGCAGGCTCACGACACACAAAGATTTATCAAGCAGAGAACAAGGATAATAATAAGT TATGGGTTGCAGTTGTTTTTCAGAGCCTTATTTTCTGTTTTTCAAACAAGTAATTGTTGA GGTGAAATGCGCATAACACAAAATTAACCGAAGGAGTGGGAACCACCGAGCAGCATTCGG CATACTCAAAGTGATGTGCCATCACCACCCCACTCACCCTTAGTCAGAATCAGCTCCTGA CTGACTGCGGCTTCTCATGCTTTCACTCAATGTTACCTTCTCGAGCCTGTCATTCCTTTC TTTCATCTTTTCAATTGGCCCCATCTGCACCTGGCCTCATTTCTGTCCATGGCTTTGTAT CTAGTCGCTGCAAGATGCACTATGTGTATATGCACGTGGAAATGTCCATGGCCAGAGTGA GGAACTGAAAGGATGGATGTCTTTTTGAAACTGAATGAGGAAGACACCTACTTTTGTTGA CAGAAGAGAAAGATGAATGGAACATCATGGAGGGTCTTCCAGGAGCCCTCTCTCATACAG AGGAAGCCTGTGAACCATTTTTTATTCTTTCTCTTGGGCACAGACATTTCTTTAAACATG TGCTGACCTTCTGCTTGGAGGTCTCCTTGAGGACATTGTCTCAGAAATCTGTGTTGCAAA ATATTAGAACTGATCACTCATCCCTTTCCACTGTTAAATTTTCTCTACTATCTCACCTTA GGCAATATAAAGTCCTGGTTCACTCTCAGGAACGAGAGCTGACCCAGTTAAGGGAGAAGT TACAGGAAGGGAGAGATGCCTCCCGCTCATTGAATCAGCATCTCCAGGCCCTCCTCACTC CGGATGAGCCGGACAACTCCCAGGGACGGGACCTCCGAGAACAGCTGGCTGAGGGATGTA GGCTGGCACAGCACCTCGTCCAAAAGCTCAGCCCAGGTGAGGTGGCCATAGGCCCTGATG ACCCAAAACCCCAGGCTTATGAGAGACTTCAGACCTCCATACTTTCACAATGACATTTGT ATCGGTGGTGTTTTTTCCCACTAAACGTATGTGGCCGTGACATAAGTGACATAACCAGGA CTTCCTGGGTAAGAACAGAGGTGGGAAACCGATTGGGTTGGAGGTCACAGTATTTCAAAT GTCCCTCCTCCCTTGATGGAAGGTGGTCTTTGGAGCAAGAAGCTGCACGTTTCTAGTTTT AAAGGACAGGAAGGAGGCTGTGACGGGAGGGCGCTTTTTAGAGTGAAAAGAGCTCTGGAC TCAGAAGGCAGGTTCCCAGGCTGTCTCTTTGGCAATGTTCTTAGTAACTGTCGGTGAGTG AGTGATTTATCCTTCCTGAGTTTCTCTGTCTCCATCTGCAAAGGCAGGCAAATTGTCTCT TGCAAGAGTCTGAAGCATCCAAATGTGGGAACACTTAGGACTGCTTTTCAAAATGAGATA AAGCCCCTCGCCATGTGGTGTTAGAGAAGGCACTTGATGTGGGGGCATTTGGTGGTAGGA AGTGCTTGATACTGGAGCACTCTTCATGGAGAGAATGTCCCTGAATAACAGGGCAGAAGC CACATGGAGGGCCTGTGCAGTCTCCTGATGCATAGAGGACTGTAGGGCAAGTTTGTCCTC TCCTAAGAGAAAGAATTAGGTTTGAAATGTGAACTGTGACAGGACACCAAGCCCGTGCCT GGGAATCAGACCTGTAGCCAGATGGGGGAGACAGCTGCCAAAGTTCAGAGAGAGGCTGTA GGAGCCTCCATGATATGGGGAGCAAAAGGTCTTTTCAGTATTTGGCCACATCTTGATGGT GGCCCTCCAGATCAGAAATGCATTGCCTGATGGATCGGGAAACCATGCCAGGGCATTTTG TTAACGATAAAACATGAGAGCTTTCAGCTGAACAGTGACCATGCCTAGATGTTCATGTCT GTGTGCACATTCGGCTGACTGTGCTTGCAGAGTGTGAATTGGGAAATATCTGAATGAACA CTTCTGTATTTACAGAAAATGATGACGATGAGGATGAAGATGTTAAAGTTGAGGAGGCTG AGAAAGTACAGGAATTATATGCCCCCAGGTAACGCTGAATAATCGGGAGCAAGTAATGGG TGGTAACATATGAAAAAGGTCTAGGAGGCACACCCTCTCTGGCATCTATGATGGGCCGAA AGCCTGCATTCCCTTGGCCACAGTATGAGAAACTCAAGCCAGCTTGGACACAGGGTGTGG CAGCTGTTGTGTTTCTCTGTGTGTGGTGGGTGTCATGTCTGTACCGTACAGGGATAGCTG AGTTTTCATCCTCCTCGGCTCCTATCTGTCCAGTGCAATGAACACCAGTTGCTGTCTTCC TCTCTGGCTCCCATGGCTGCCATGCTCTGTTGCAGAGAGAAGAGGATTGCCTGTTCCCTC TTAAAGGGATCCTCCTGTTTGCTTTCTTGGACCACTCTCTTAATGCCTCCTGTCGAAACC AGCTAGCACTCCCTGGTGTCCAATCCCTCTGTGTTTAGTCTTCTGTCATCTCTATCCCAC CTGGCTCATCAGGGAGGTGCAGAAGGCTGAAGAAAAGGAAGTCCCTGAGGACTCACTGGA GGAGTGTGCCATCACTTGTTCAAATAGCCACCACCCTTGTGAGTCCAACCAGCCTTACGG GAACACCAGAATCACATTTGAGGAAGACCAAGTCGACTCAACTCTCATTGACTCATCCTC TCATGATGAATGGTTGGATGCTGTATGCATTATCCCAGGTAGCCTCTATTTTCCTGTGTC TCACACCTTTTCCTATGCTGAGGAATATAAACTCTGAAGACAGGCTCTATACACACAGAT TGGTTTTAATAAAATCTATTATGGTATTCTTAACAGAGATATCAAGGAGGTTTTCTGTCC TTCTCAGCTCATGTCATGCCTTTGTCTCACAGTCCCCAGTGTCAAGTTACTGGACCCCAG ACAAGTGTGACAATCTCATAGTCACCTGAGTGCAGGAGGTACACAGGAAGTATCTGTGAG GCCTCGTACCTTTGATTCAGTATCTCTTGTCACCTGTGATTAAGTCGTCTGTCCCTGAAC AATGTCCATGAAATTTCTCTGCCTTTTTAAGGCGACTGGCAGCCTTGCCTTTGTGTTTGG AAATATTGTTCCCCAGGCTTCACTGCTCTCAGCTTTAATCTTGATCTCCTTTGAGTCTGC TTGGTTAGCTGCACAGTCACCTTGAAATCAGGACAGAAACTTTTCTTTTTTACTTTGCTG ATATAGTTCCATAAAGCAAGGCTGGACCCTGGTTCTCCACCCCATCAATGCAATGGCTGA TGCAATGTTTTGTAGCATCATAGATTCTCTCTCTCTTTTTCTTTTCTTTTCTTTTTCTTT TTCTTTTTTTTTTTGTGATGGAGTCTGGCTCTGTCACCCAGGCTGGAGTGCAATGGCTCC ATTTTGGCTTGCTGCAACTTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCC TGAGTCGCTGGTACCACAGGTGCTCAGCACCACATCTGGCTAATTTTTGTATTTTTATTA GAGACGGGGTTCCCCCATGTTGGCCAGGCTGGTCTTGAACTCATGACCTCAAATGATTCA CCTTCCTTGACCTCCCAAATCACAGATTCTTTTTAATGCAAGAGTTGTTAGAATTTATCT ATCAGTCGAGTTTCATGTGTAGATCCCTCTAAACATTTAATGTCCATGTTACCTGGTGAT ATAAGTCAGTATTGCAACAACACTCCTAGAAAATTGTTTGACCAATTATTGGCGACTTTG GGGGGAAAATTTTGTTTAACTTTGCATAGACTCAGGCAGGGAATATGGCATTATGGTCTA CCCATAGAGGGAAATTTTGGCCTGTGGGTCTGGAAAGCAGGGTCATCTACTTCTCACCAG AGTTAATCTAGGGCACCCTGGAGTGCTCCTGTCAGAATCCATATTCTTGCACTGAGAATA GTTATGTCCTTGTCCTATGACTGGACACTGATTTGGTCATATGTGGAGTGTGAATTGCTT AATGTGACCTGCTTCTCTGAATTTATTTCCAGAAAATGAAAGTGATCATGAGCAAGAGGA AGAAAAAGGGCCAGTGTCTCCCAGGTAATGCCATGGAATTGTGGGCTGTTAATTCAATAG TGGCAGCTGGAGTTTGTAGATTTAGAGAAAATGAGGAAGCAATGAATAGAACTTTTTATT CCATTCACCCAGCTACAAGTTGTCCTTATTAACAATGTTGTACATTATTTGTGGCCCTTG TGTTGGTTTTAATTTCGTAGTCCTCTCAAGATAGGAACTTGCAATCAGATGAGCCAGGTG AACTAGCCAAACAGGGATTTCTTGTTGATCTTTTCAAAAAACCAGCTCCTGGATTCACTG ATTTTTTTGAAGGGTTTTTTGTGTCTCTATCTCCTTCAGTTCTGCTCTGATCTTAGTTAT TTCTTGCCTTCTGCTAGCTTTTGAATTTGTTTGCTCTTGCTTCTCTAGTTCTTTTAATTG TGATGTTAAGGTGTTGATTTTAGATCTTTCCCTTCCTTGTGGGCATTTAGTGCTAGAAAT TTCCCTCTCCACACTGCTTTAAATGTGTCCCAGAGATTCTGGTATGTTGTGTCTTTGTTC TCATTGGTTTCAAAGAACATCTTAATTTCTGCCTTCATTTCGTTATTTACCCAGTAGTCA TTCAGGAGCAGGTTGTTCAGTTTCCATGTAGTTGTGCAGTTTTGAGTGAGTTTCTTAATC CTGAGCTCTAATTTGATAGCACTGTGGTCTGAGAGACAGTTTGTTGTGATTTCTGTTCTT TTACATTTGCTGAGGAGTGCTTGCTGAGGAGTGCTTTACCTCCAACTATGTGGTCAATTT TGGAATAAGTGTGATGTGATGCTGAGAAGAATGAATATTCTGTTGGTTTGGGGTGGAGAG TTCGTAGATGTCTATTAGGTCTGCTTGGTGCAGAGCTGAGTTCAAGTCCTGGATATCCTT GTGAACCTTCTGTCTCATTGATCTGTCAAATATTGACAGTGGGGTGTTAAAGTCCCCCAT GATTATTGTGTGGGAGTCTAAGTCTCTTTTTAGGTCTCTCAGGACTTGCTTTATGAATCT GGGTGCTCCCGTATTGGATATATGTACATTTAGGATAGTTAGCTTTTCATGTTGAATTGA TCCCTTTGCAATTATGTAATGGCCTTCTTTGTCTCTTTTGATCTTTCTTGGTTTAAAGTC TGTTTTATCAAAGACTAGGATTGCAACCCCTGCTTTTTTTTGCTCTCCATTTGCTTGGTA GATCTTCCTCCATCCCTTTATTTTGAGCCTATGTGTGTCTCTGCACGTGAGATGGGTCTC CTGCGTACAGCACACTGATGGGTCTTGACTCCTTATCCAATTTGCCAGTCTGTGTCTTTT AATTGGGGCATTTAGCCTATTTACATTTCAGGTTACTATTGTTATGTGTGAATTTGATCC TGTCATGATGATGTGAGCTGGTTATTTTGCCTGTTAGTTGATGCACTTTCTTCCTAGCAT TGATGGTCTTTACAATTTGGCACGTTTTTGCAGTGGCTGGCTGGTACTGGTTGTTCCTTT CCATGTTTAGTGCTTCCTTCAGGAGCTCTTGCAAGGCAGGCCTGGTGGTGACAAAACCTC TCAGCATTTGCTTGTCTGTAAAGGATTTTATTTCTCCTTCACTTTTGAAGCTTAGTTTCG CTGAGTATGAAATTCTGGGTTGAAAATTCTTTTGTTTATGAATGTCGAATATTGGCCTCC ACTCTCTTCTGGCTTGTAGGGTTTCTGCAGAGAGATCCACTGTTAGTCTGGTGGGCTTCC CTTAGTGGGTAACTCGACCATTCTCTCTGGCTGCCCTTAACATTTTTTCCTTCTTTCAAC CTTGGTGAATCTGACAATTATGTGTCTTGGAGTTGCTCTTCTCGAGGAGTATCTTTGTGG TGTTCTCTGTATTTCCTGAATTTGAATGTTGGCCTGCTTTGCTAGGTTGGGGAAGTTCTC CTGGATAATATCCTGAAGAGTGTTTTCCAACTTGGTTCCATTCTCCCCGTCACTTTCAGG TACACCAATCAAATGTAGATTTGGTCTTTTCACATAGTCCCATATTTATTGGAGGCTTTG TTCATTTCTTTTTACTCTTTTTTCTCTAAACTGCTCTTCTCACTTCATTTCATTAATTTG ATCTTCAATCACTAATACCCTTTCTTCCACTTGATCGAATCGGCTACTGAAGCTTGTGCA TGTGTCACGTAGTTCTCGTGCCATGGTTTTCAGCTCCATCAGGTCATTTCAGGTCTCCTC TACATTGTTTATTCTAGTTAGCCATTCGTCCAATCTTTGTTCAAGGTTTTTAGCTTCCTT GTGATGGGTTTGCACATCCTCCTTTAGCTCGGAAAAGTTTATTACCGACTTCTGAAGCCT ACTTCTGTCAGCTCATCAAAGTTATTCTCCGTCCTGCTTTGTTCCATTGCTGGTGAGGAG CTCTGATCCTTTGGAGGAGAAGGGGCGCTCTGGTTTTTAGAATTTTCAGCTTTTCTGCTC CAGTTTGTCCACATCTTCGTGGTTTTATCTACCTTTGGTCTTTGATGCTGGTGACCTACA GATGGGGTTTTGGTGTGGATGTCCTTTTGTTGACGTTGATTCCTTTCTGTTTGTTAGTTT TCCTTTTAACAGTGAGGTCCCTCAGCAGCAGGTCTGGTGGAGTTTGCTGGAGGTCCACTC CAGACCTTCAAACAGGGATTTCTTGGTGTCACCTGTTCTCTCCCATGTGTTTAAATCCAG GGAGAGAATGTATAAATGCTTTCTGCTTATTTTTTATTAGTGTGTTTGCTAGTATTTGTG TAAGCAAAGAAATTGAAAAAATAAACATATTATATCAAAATATTGTAAAAAGGGGACCCT TAATACACAAGATCTGTGTCTGCACTGCCTCAAGAGCTCTGTTCACTTGAATGCTGCATG TAAAATTCATCCCAATTTAGACGAAGTAGTTGAAGCCCTGTGTTAGTTCTCTGTGCTGCA AGTCATGATGGTAGTTTACAGAGAGAGTCTGGGTGCCCTGCATTGGCTGATCTGTGGCAA ATGTACTGAGCACGTGCTGCCCATTTTTGTTCGGTCCTCAGAGCAGTCACCCTCCAGCCT GCATTTAGAAGGATAGTTTTATTTCTCTTGAAGGAAAAATGCCTTTGGTTTCTGTGAGCA CTCCATTCTGTCTCCCATCAGATCATCTGGAAGGTTTTGTTGTCTAATCTCTGTTGGTTA TATCTTCTGTCATCCCTGTCCTGCCTGGCTCATCAGGAATCTGCAGGAGTCTGAAGAGGA GGAAGCCCCCCAGGAGTCCTGGGATGAAGGTGATTGGACTCTCTCAATTCCTCCTGACAT GTCTGCCTCATACCAGTCTGACAGGAGCACCTTTCACTCAGTAGAGGAACAGCAAGTCGG CTTGGCTCTTGACATAGGCAGTGAGTACTCCATTTTGAAGGTGATAAAGCTCCAGTTCAT GTCCCAGGTAGACCCCATAATCTTTGGGCCTTGTGACCCTGGTTGGGCTGAGAGTTGCCA TCACTGTGGGTGGAACCTATATATCAATGTAGATTTCAATCACTCTGGAATCGAGTCTGA AGCACAGGCGTGGGGTGGGTCAGTGAGCTTTGCTCTCTTCCTAGTCTCAGGCCATGCCTG TGCCACCCTGGACTGACTGTCAGGACACTGAACACAAGACGGGCGTGGCAAACTCACACC AAGCTGTGCAGCATATGTCCAGGAGTTGTCTGTCAGATCAGCTCACCTGAGTTAAACGTC TCTTGCCAGCTACAAAGTTCTTTATGAGTTTTGTTCCCAAAGCATGTCTGTGCAGTGCTT TACCTGCCCAAGGCCAGTGTCACCCTTGTCTACCTCTCCGTGGAAGATGTGACCCAGGTT TCACTGAATTTTTCCCCCTTTTCTGTGTCTTCTAAGTTGGCTTGTCATAGCTCATCTGTC CATCATCTTGCTGGTATGTTTTCTAGATAAATGGCTGACTTTTCACCCACAAAAGCCATG ATAGCTGATGCTTCTGTGTAGAACCAAGTGTCACTTTGACTCAAGAGCTGGTACATTGCA CCCCTCCATCAAATCTCAGTGTCCACAATCTCATAAACTATCAAATCTGGGTATTTGAAG AGAGAAGCCTGAATATTGCAGTATCTCTCCTATGAGGCATTAGAATGATTTGCCTCAAAT CTATTGGGAAAAACATTGCTCATTTGTGTACACAAACCTAGGACAGAGCACACTGGGAAG ATCACATTCCAAAACAGGGGCATTTTGCCCAAGGCTCATGAAAGGAACCAAGTCAGTTCT CTCAAGACTTGCCCTCAGGCCTCCTGGTATATTTCTCTCAAAGTCTCCTATTCTCACACT GAGAAGACTGATGTCCCTGTGTTAGGATTGGACAGAGGAATGTTTCCGTGTGCAAGGAAG AACTGCTTCATGTAAGAGGCCCTGTCTGAATTTATTTGCAGGACATTGGTGTGATCAAGT GAAAAAGGAGGACCAAGAGGCCACAAGTCCCAGGTGAGTCTGAGAAATTATGGACAGTTA ATTTGATGTTGACACCTGGAGATGCCAAGTCCGGGGAAAGCAGTACATGCTGAAAATGAT GATTTCATCTTGTCAGACAAGTCTGAATTATGTCTACTAACATTGCTTTTGGTTCTCATT ACAGTAAATGTTTAGGTTTCCATTTCTTCCTATCCTTCTCATTTACTAACCTAGTGAAGG TTGACCATACTTCAAAAGCTGTATTCTCATGGTGACTGCAGGGAAGCTTGAGCACATTTT ATGCAAAATTGTTGAGCCCACTCTTTTCATGATCACTGTTCATTGTGTGTCCTGAAGGCA CAAATATAGAGTGTTCTTTGACTCTCTCATCAGTGTGTCACCTGGCCAATTCACTGAGCT CACTATCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTATGTGTATGTCTTTCTCTTTCATCCTTTTCTACCTGGCCCTGGTCTGTCCCAAC ATGAAGGCAATAATTTGTTACCTCATTAATAGATCTGTCCTTTTTCTTTTCAAACAGTTC CTTATGTTACCCATGAAATCTAGCTGGGGCTGTGTGGTTTCTGATTCCCCCTGGCTTATT CTTTACTTTTCCTACTTTTCCAGGCTCAGCAGGGAGCTGCTGGATGAGAAAGAGCCTGAA GTCTTGCAGGACTCACTGGATAGATTTTATTCAACTCCTTTTGAGTACCTGGAACTGCCT GACTTATGCCAGCCCTACAGAAGTGACTTTTACTCATTGCAGGAACAACACCTTGGCTTG GCTCTTGACTTGGACAGTGAGTACCTTACTATGAAGGTGATAAGACTCCACCTGGTCCTC CAGATATGGGTGATATTCCTGTTCCAAGTGGCCCTTATTGACCCGAGAGATGTCATTGCC ACAGGCAGGACCCGTGGGCGCATAGAGGTTGTAATGAAATTGTAGTTTCAGTTGGAAGCC CAGACATGAAATGGGTCAGTGAGCATGGCTCTATTCCTAGTCTCCAGCCATGCCTGTGGC AACCTGAGCCCACTCTCAGCACATTGGACCCAGGCAGGTGTAAAAAATTCACAGAACCAT GATTTGGACTCAAGGGTTTGTAGATTTCCTCCTTCATTCAAATTTCAGTGTCTTGCAACC ACGAATGAGCTGGGCATTTGATGAGACAGGGCTGAATACTGCAGTTTTCCTCCTAGAAAT CATCTGGGGCATTTTCTTTGAATTGATGGGAGCAATAAGGCATAACTGTTTGCACAAACT TGGGATAAATGATTTTGGGATAACTGTCTACCAGAATAGGGACATTTCACCCTTGGTTCT GAGATGCAAACCAAAGAATCTCTATCATGACCAGCTTTGAGGCCTCCTGAAGTATATCTC TCACATTGTCCTGTTCTCATGCTGAGGAGCCTGAGGTCCCTGTGTGGGGATTAGACAGTG GACTGTTAATGGGTGTAGGTGAATTGGCTTATCTTGTCTGTCCCTGTCTGAATTTATTGC AGGAATGAAAAAGGACCAAGAAGAGGAAGAAGACCAAGGCCCACCATGCCCCAGGTAAGT TTGAGCAATTGTCAACAGCTAATTCTGTGTTGACACCTGGAGACTCCTGGTTCAGGGAAA GCAGAGCAGGCCGACATTATCGATTACATGTTTTCAACCAAGCCTGAATTATTCCTACTC ACATTGCTATTGGTTTTCATTGCAGTAGATATTTAGGTTTCCGTTTCTTCCTCCCCTTAT CACTTACTAACCTACTGTAGGTCGACCATACTTCAAAAGCTGTATCCTCATGGTGACTGC ATGGAAACTTGAGCACATTTTATGGAAAATTATTGAGCACAGTCTTTTCATGATCACTGT ATGCTGTGTGCCCTGAGGGCACTAACTCAGAGTGTCCTGTACTCCCTCCTCAGTGTGTCA CCTGGACAATTCAGTGAGCGCTCACTCTCTCTCTCTCTGCCTCTGTCTCTCTGTCTCTCT GTCTTTCTCTTTCATTCTTTTCTGTTTGGCCCTGTGCCATCCCAACTGAGGGCAATAATT TGTTACCTCATTAATGGATGTATCCTTTTTCTTTTTTAACCACTTCCTAATGCTACCCAT GAAATCTAGTTGGGGCTCTGTGGTGTCTGATTTCCCCTGGCTTATTCTTTACTTTTTCTA CTTTTCCAGGCTCAGCAGAGAGCTGCCGGAGGTAGTAGAGCCTGAGGACTTGCAGGACTC ACTGGATAGATGGTATTCGACTCCTTTCAGTTATCCAGAACTGCCTGATTCATGCCAGCC CTACGGAAGTTGCTTTTACTCATTGGAGGAAGAACACGTTGGCTTTTCTCTTGACGTGGA TGGTGAGTACCTTTCTATGAGGGTGATAAGGATCCACTGAGTTTTCCGTATAGAGATCCT ATTCCTGCTCTAAGAGGCCGTTACTGAGCTGAGAGATGTCATTGCTGCACTGAGGACCTA TAGGCACATATAGGTTGAACGAAACTCTAGTTCTACCTGGAAGCCCAAACATGGGATGGG TCAGTGAGCGTGGCTCTCTTCCTAGTCTCAGGCCATGCCTGTGGCACTCTGATTCTACTC TCAAGGCATTGGACCTGGGCAGATGGGACAAATTCAGAGAACTATGATTTTGACTCAAGG GTTTGTAGATTTCCTTTCTCACTCTAATTTCAGTGTCTAAAATCCTCACAACTATGAACA ATCTGAGTATTTGATGAGACAGGGCTGAATATTGCAGTTTTTCTCCTAGAAATCGTTTGA GGGCATTTGCTTTAAATTGATTGGAAAGATATGGCATAACCGTTTGCACAAACTTGGGAC AAATGATATTGGGATAATGATCTACCAGAATAGGGACATTTTACCCTTAGTTTCTGGGAC AAAAACCAAGGAATCTCTATCATGACCATCCTTCAGGCCTCCTGAAATATATCTCTCACA GTGTCCTATTCTTATGCTGAGGAGCCTGAGGTCCCTGTGTGAGGATTAGACAGTGGAATG TTATGTGTGTAGGGGAATCAGCTTAATGTGTCTGTCCATGTCTGAATTTATTGCAGAAAT TGAAAAGTACCAAGAAGGGGAAGAAGATCAAAAGCCACCATGCCCCAGGTAACTTTCAGC AATTGTGGTCGCTTAATTCTGTGTTAACACCTGGAGACAACAGATCCAGGGAAAACAGTG TGTTTGATTTCATGTTTTCAATGAAGGCTGAATTACTCCTGCTGACATTGCTATTGGTTT TCATTGCAGTAGACGTTTAGGTTTTCATTTCTTCCTCCCCTTATCATTTACTAATGTACC ATAGGTTGACCATACCTCAGAAGTTGTACCCTTATGGCGACTGCATGGAATTTTAAGCAC ACTTGATGGAAAACTATTGAGCTCACTCTTCTCATGATCACTGTTTGCTGTGTGTCCTGA GGGCACTAACTCACAGTGTCCTTTTACTCCCTCATCAATGTGTCACCTGGCCAATTCACT GAGCTCACTTTCTCTCTCTCTCTGTCTCTCTCTCTCACTCTCTGTCTTTCTCTTTCATTG TTTTCTACTTGGCCCTGTTCTATCCCAACATAAAGGCAATAATTTTTTTACCTCATTAAT GGAACTATCCTTTTCCTTTTTTGACCACTTCCTTATGTTACCCCTGAAATCTAGTTGGGG CTCTGTGGTGTCTGATTTTCCCTGGCTGCTTCTTTAGTTTTGTCTCCTTTTCCAGGCTCA ACGAGGTGCTGATGGAAGCAGAAGAGCCTGAAGTCTTGCAGGACTCACTGGATAGATGTT ATTCGACTACTTCAACTTACTTTCAACTACATGCCTCATTCCAGCAGTATAGAAGTGCCT TTTACTCATTTGAGGAACAGGACGTCAGCTTGGCCCTTGACGTGGACAATAGGTTTTTTA CTTTGACAGTGATAAGGCACCACCTGGCCTTCCAGATGGGAGTCATATTCCCACACTAAG CAGCCCTTACTAAGCTGAGAGATGTCATTGCTGCAGGCAGGACGTATAGGCACATGTAGG TTTGAATGAAACTGTAGTTCCCTTTGGAAGCCCAGTCATAGGATGGGAAAGTGGGCATGG CTCTATTCCTATTCTCAGACCATGCCAGTGGCCACCTGTGCTCAGTCTGAAGACGTTGGA CCCAAGTTAGGTGTGACACGTTCACACGACTATGTAGCACATGCCGGGAGTGATCTGCCA GACATTCTAATTTGAACCAGATATCTCTGGGTAGCTACAAAGTTCCTCAGGGGTTTCATT TTGCAGGCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTTTGTGTTTAG CTCATCCAAAGGTGTTACCCTGGTTTCATTGAACCTAACCCCATTCTTTGTATCTTCAGT GTTGGTTTGTTTTAGCTGATCCATCTGTAACACAGGAGGGATCCTTGGCTGAGGATTGTA TTTCAGAACCACTGACTGCTCTTGACAGTTGTTAACCCACTAGGCTCCTTTGAGTAGAGA AGCCATAGTCCTTCAGCCTCCAATTGATATCAATACTTAGGAAGACCACAGCTAGACGGA CAAACAGCATTGGGAGGCCTTAGTCCTGCTCCTTTCAATTCCATCCTGTAAAGAACAGGA GTCAGGAGCCGCTGGCAAGAGACAGCATGTCACCTGGGACTCTGCCAGTGCAGAATATGA ACAATGCCATGTTCTTGCAGAAAATGCTTAGCCTGAGTTTCATAGGAGGTAATCACCAGA CAACTGCAGAATGTAGAACACTGAGCAGGACAACTGACCTGTCTCCTTCACACAGTCCAC GTCACCACGAATCACACAACAAAAAGGAGGAGAGATATTTTGGGTTCAGAAGAAGTAAAT GATAATGTAGCTACATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGT TGTTGTCATTGATTTTGGTGACATGGACTTGTTTGTAGAGGACAGGTCAGCTGTCTGGCT CAATGGTCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTCAGCCTAAACG TTTCATCAAGAACACTACAGAGTCGATACTGTGAGTTTCCAACCTCAGCCCATCTGTGGG CAGAGAAGGTCTAGTTTGTCCATCAGCATTATCATGATATCAGGACTGGTTACTTGGTTA AGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATGATGAAGTATTTGG GAGAGTGGTTTTTCAAAGTAGAAATGTCCTGTATTCCAGTGATCATCCTCTAAACGTTTT ATCATTTATTAATCATCCCTGCCTGTGTCTATTATTATATTCATATCTCTACGCTGGAAA TTTGCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGTTGAAAAAAAA ACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAA CTTTTGCCTATCACTCTGGACTGTTGGATTGTTTTTTACATTCAGCGTTATAATCTTTTG TTATGCTGATTGGTTTTGGTGGGTACTGATGCGAATTAATAAAAACATTTTCATTTCC bcftools-1.21/test/csq/ENST00000318249.2/ENST00000318249.2.fa.fai000066400000000000000000000000211467060157400220360ustar00rootroot000000000000001 44878 23 60 61 bcftools-1.21/test/csq/ENST00000318249.2/ENST00000318249.2.gff000066400000000000000000000112541467060157400214660ustar00rootroot000000000000001 ensembl_havana gene 1 44878 . + . ID=gene:ENSG00000142794;Name=NBPF3;biotype=protein_coding;description=neuroblastoma breakpoint family%2C member 3 [Source:HGNC Symbol%3BAcc:25076];gene_id=ENSG00000142794;logic_name=ensembl_havana_gene;version=14 1 ensembl_havana transcript 11 44772 . + . ID=transcript:ENST00000318249;Parent=gene:ENSG00000142794;Name=NBPF3-201;biotype=protein_coding;ccdsid=CCDS216.1;tag=basic;transcript_id=ENST00000318249;version=5 1 ensembl exon 11 221 . + . Parent=transcript:ENST00000318249;Name=ENSE00001542593;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001542593;rank=1;version=1 1 ensembl exon 4821 5092 . + . Parent=transcript:ENST00000318249;Name=ENSE00003631247;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003631247;rank=2;version=1 1 ensembl CDS 4960 5092 . + 0 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 28561 28770 . + . Parent=transcript:ENST00000318249;Name=ENSE00003487448;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003487448;rank=3;version=1 1 ensembl CDS 28561 28770 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 30505 30607 . + . Parent=transcript:ENST00000318249;Name=ENSE00001724864;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001724864;rank=4;version=1 1 ensembl CDS 30505 30607 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 31442 31656 . + . Parent=transcript:ENST00000318249;Name=ENSE00001617203;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001617203;rank=5;version=1 1 ensembl CDS 31442 31656 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 32716 32788 . + . Parent=transcript:ENST00000318249;Name=ENSE00001618625;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001618625;rank=6;version=1 1 ensembl CDS 32716 32788 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 33253 33458 . + . Parent=transcript:ENST00000318249;Name=ENSE00001316812;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001316812;rank=7;version=2 1 ensembl CDS 33253 33458 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 34773 34824 . + . Parent=transcript:ENST00000318249;Name=ENSE00003569827;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003569827;rank=8;version=1 1 ensembl CDS 34773 34824 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 38017 38180 . + . Parent=transcript:ENST00000318249;Name=ENSE00001619353;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001619353;rank=9;version=1 1 ensembl CDS 38017 38180 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 39222 39273 . + . Parent=transcript:ENST00000318249;Name=ENSE00003497364;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003497364;rank=10;version=1 1 ensembl CDS 39222 39273 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 39924 40096 . + . Parent=transcript:ENST00000318249;Name=ENSE00003594154;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003594154;rank=11;version=1 1 ensembl CDS 39924 40096 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 40803 40854 . + . Parent=transcript:ENST00000318249;Name=ENSE00003524606;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003524606;rank=12;version=1 1 ensembl CDS 40803 40854 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 41470 41642 . + . Parent=transcript:ENST00000318249;Name=ENSE00003655848;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003655848;rank=13;version=1 1 ensembl CDS 41470 41642 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 42357 42408 . + . Parent=transcript:ENST00000318249;Name=ENSE00003531648;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003531648;rank=14;version=1 1 ensembl CDS 42357 42408 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl CDS 43016 43259 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 43016 44772 . + . Parent=transcript:ENST00000318249;Name=ENSE00001277853;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001277853;rank=15;version=3 bcftools-1.21/test/csq/ENST00000318249.2/ascii-art.txt000066400000000000000000000002301467060157400214230ustar00rootroot00000000000000 4958 AGA A 4960 .....eeeeeeeeeee 1234567890 ATG CACACTGGAGATGCCACTGAC CACACTGGA--TGCCACTGAC CACACTG--GATGCCACTGAC bcftools-1.21/test/csq/ENST00000318249.2/synonymous-start-lost.txt000066400000000000000000000002031467060157400241240ustar00rootroot000000000000004958 AGA A start_retained|NBPF3|ENST00000318249|protein_coding|+ 4958 AGA A start_retained|NBPF3|ENST00000318249|protein_coding|+ bcftools-1.21/test/csq/ENST00000318249.2/synonymous-start-lost.vcf000066400000000000000000000004471467060157400240750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 4958 . AGA A . . EXP=start_retained|NBPF3|ENST00000318249|protein_coding|+ bcftools-1.21/test/csq/ENST00000318249/000077500000000000000000000000001467060157400166535ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000318249/ENST00000318249.fa000066400000000000000000001311211467060157400210060ustar00rootroot00000000000000>1 1:21766621-21811498 GGCGCAGGCACAGGCGAGGGGTTGGGTGGCGGTTGAGACAGCGGCGGTACTGGGATGGGT AGGTGAGGATCCCGAGACTGAGTGAGCTTCTGCGCGCGGTGCTTTTGGGAACGCGGGACT GGCAACCTGCGGCGCCAGGAGCTGGGCCGAGGCGCGGCGGCGCGGCTGCGGGCCGCCGTC TGGATGGGAAGTTACGGCGAAGTCCACCCAGCGTTTCTCAGGTGAGGGCGCCGCGCCAGG CTGGACGGGCGGTGAATCCGGGACCGGCGGGCGCACACCTGGGTCGAGGCGCGGCCGTCG CAAGTTTTGTTGCGCGAGCGCGGGGGCGGGTGGGAGGTGGGGGGTGTGGGGGGTCGTGCA CCGCCGGGGGCTGAGTTCCCCGCGCTGGATTCTTCGCCTGCCGCTGCCGCCCTCAGCCCA GCTCTCGTGGGCGCTGGGGAAGAAACTCGCTGGCGGGTGTTCTGTGGCATCCCAGGGGGT GGAGGGACGGAGCAGCTTCGGGGGCACGTCCTCCTATATCCTGTAGAGGACACTGACTCC GCACCCCACCCTCGAGGCCGGAAATCGGTTCCCTCTGCGGGCCTGAGAGGCGAGAGCGCT CGCGCCCCTGACTTGCAAAGTTGGGGTCTTTACTGGCCTCCGGGCTTCTGCTCCTGGCGG TGTCTCCAGGCTGGTGATGGGCAAGCCAGGTGTGCCAGGTCCAGGATGCACATGAGGAGC GTTTGTAGCCATCACTGAATCACCTCCTGACTAGCGGGGCAAGCCTCAAATGAACCGCAG GATTTCGGCTAGGTTGGATTGTGGGGTTGCTGTTTGCACTCCGAGGAGTTGCTGTGGTTT CCCTGTGCCTGTCTGTCTGTCTTTCTGGCTTCTTAGATCATCATCTCATGTGGCGTCCTT TCACCGAAGAGTTAACCAAGACGTTTGGCCTAGTTTCCTTGCTTTCCTTCTGTCTTTTGC TGCTAGAGCTGCTTTCGAAAAGAAGTCTTTTCTGGCAGTGGTACCTTTTCTTTGGGTTAC GGTGTTGTTCATCCTTTCTTTGCCAAAGGAATGAATCCCAGTGCTTCACGAAGTTAAAGA TCTGCTGGTAGTGTTTAATCTGTTTGGAGCTGATATGCGTTAGTAGCTTTCTTTTTGTTT TTAAATTTTATTAGTAAAATTTCACTAGTGAACCAGAAGCTATTTTTTTCTATTCTGAAA TGCTGGCTTTAAGATTTCTGATAACTTTGCGTCAAAGAAATCTTGGAAAAGTTACTGAAG TATACAGAAGAAGTTCACAATTTTAAATGTGCAGGGGGCCCGGGCGCAGTAGATCACACC TGTAATCCCAGCACTTTGGGACGCCAAGGTGGGTAGATCACTTGAGCCCAGGATTTCCAC ACTAGCCTCGGCAATGTGGCAAAACCCTATCTCTACTAAAAATACAAAAGTTAGCTGTGT GTGGTGGTGTGTGCCTGTAGTCCCAGCTACCCGGTAGGCTGAGGTGGGAGGATCACCAGA GCCCGGAAGGTTGAGATTGCAGTGAGCCGTGATCATGGCAGTGCACTCCGACCTGGATGG CAGAGTGAGAGCCTATCTCAAAAAAAAAAAAAAAAAAAGTAATGAATTTTGACCAAGTGA ACCACCACAGATCAAGAAATAGAACATTACTAGACTGGAGTATATTTTTGGAGTGGCATT GTTGGTTTTAGAGGTATATGAATGATAAAACTTTAGTATTACATATTGTTGAACATTTTC CCAAAGTGGTTGTACCATTTAGCAAGGATATTCTGGTTACCCCACATCCTCGCTGATGCC TGTCAGTTAAAAATCATTTTGCCATTCTAGTAGGGGTGCAGTAATATATCAGTGTGGTTT CATTGAGATTGAGTATCTTTTATTGCCATTTATGTGTCTTCTTTTGTGACATGCCTGTTA AACCTTTTTATCCAGTTTTCATTGATATGCTTGTTTTCCTGTTGATTTGTAATACTTTAT TCTGGATATGCCTCCTTTCTAGGATTTATATGTATTGCATTTCCCTTTTTTCAATCTGTA GCTTGCGTTTTCACTCTTTTATGTTGTTTTTTCATGAATGGAGATTCTCTGTTTTTTTTC TTTTTGAAACAGGATCTCACTCCATTGCCCAGGCTGGAGTGCAGTGGCACAATCACAGCT CACTGCAACCTTGACCTCACAAGGCTCAGATGATCCCCCTGCCTCAGCCCCCAAGTAGCT GGGACCTACAGGGGAGTACCACCACACTCAGCTGTTTTCTGTATTTTTAGTAGAGATGGG GTTTTGCCACATTGCATAGGCTGGTCTGGAATTCCTAGGCTCAAGTGATACACCTGCTTC GGCCTCCCAAAGGATTGGGATTACAGGCATGAGCCACTGCACCCGGCCTGAGATTCTTAA TTTTAATGAAATTATACTTTATCAATCTTTTCCTTTATGGTTACTGCTTTTCATGTCATC TTTAAGAAATCAATGCCTAACCTAAGAGTATGAACACATTTTTCTGTGTTAACCTTATAA CAATTTTATTTCAGTTTTTGCATTTTTTTTTTTTCAGACAGGGCCTCACTCTATTGCCCA GGCTAGAGTGTGGTGGCAGGATCTCAGCTCACTCAACCTCCATCTCCTGGCTCAAGTGAT CCTCCCACCTCAGCCTCCTGAGTAGCTGCGACTATAGGCATGTGCCACCATGCCTGGCTA ATTTTCGTATTTTTTGTAGAGATGGGGTTGCAACATGTTTCCCAGGTTGGTCTCGAACTC TTGGGCTCAAGTAATCTGCCCGCTTCAGCCTCCCAGAGTGCTGGAATTACAGGTGTGAGC CACCCCACCTGGCTATGATTCACTTTTTACTACATGGATGTGTCTGCTTTATCCAGGACC ATTTATTGAAAAGACCATCCTTTTCCTTCTGCACCATGTGGCACTTTTCTTCATAAATCG ATTGACTGTATGGTCATCTGATTTATGAAATTAGTGTGGGTCTGTTTCTGTTTCTGGACC AACCTGGGTAACATAGTGAGATCCTGTCTCTACAAAAGATAAAAATAATAAATAAATGAA TAAAATTTAAAAAATAAGTGCATAGAGCAGATGGAGTCATAGGTGATAATTTATAAATGA TTGTCAGTTTCTTGGCTACATACAGGTGTTGGTAATTCAGATGTGTTGGGCGTTCAGGCA AAATGTATTAAGTGAATTATATGGTGTTCAGAATGATTGCTAGAGGTTCACTGTGACTTC AATTAGATGTTATTTGAGCCTCACAGAGCTGCAGTTTTGACTCTTTTATTTATTTGTCTT TTTGAAGTTTTTACAATCTTCCTGTCAAGGCAGTAACACTTTTATACTTAATTGTTCTTA GGTATACTTAATTAGCGAGAAAACTTTATGGATCATCCCTAAATAAGTGTTAAGCCATTT AAAGGGCTCACGTGATGTGATATAAACAATAGTATTCTACATAATAGTTTTAGGACTACA TAGAATAATTTTTTTTTTTTTCTTGAGACAGTGTCTCGCTCTGTTGCCCAGGCTGGAGTG CAGTGGTATGATCATGGCTCTCTGCAGCCTTGATCTCTCAGGCTCAAGCAGTCCTCCCAC CTCAGCCTCCTTAGTAGCTGGGTCTACAGGCATGCACCACTATGCCTGGCTAATTTTCTC CTTTTTGTAGACAGGGTTTTCCTGTAGTGCCCAGACTGGTTTCAAACTCCTGGGCTGAAA TGATCCTCCCACCTTGGCATCCCAAAGTGTTGGGATTACAAGCATGAGCCATCACACCTG GCCATTTTAGTTTTAATAATTTTTATGTTTTTCTAATTTAAAAGATTTACTAAAATCTCT TACGGCTGTTATTTATGAATATAGTATTCATTGTTGTTATTATGATGATTTTGTATGTGT TCAATCTGATTTTCAATATAAGCTACCGGCAATTAGAGATTTTGTCTCTTTTATTCACCA CTGTATTCTCAGTACTTGACCTTGCCTGGCATGAAACAGATATTGAATAAATATTTCTTA AAAGAATGAATGAATGAACATACTAATACCATATTCAACAATCTCCAAGTATCACAGTTT TCACCATCTAACAAATAAAATAGCTGTATAGAGTAGAGTCACAGTCAACCTGCCATGAAA GGAAATGTCAATGAAAAATAAACCTTCGTATGTGTAGCTGCTAAGATTTTGGGGCTTTTG TTACTGTAGTATAACCTAGCGAAAGCTCAGTGAGGCAGCATATACAATATATGTGTACAG ATAGACCAGCTAGACCAGTAGATGAGATTCCAAAGATAGTTCAATAAGCATTAACTAACA ACACCCACACTCTCTTAATTCCCTAACAAAAATAATGGAATTCTTGTTCACTAAGATCTG CCTCAAATATTACTTTGTGAAAACTTCCCTGGCTACTCTAGTATTTAGTCAGGACTCTAT TTTTTTTCCCGCCGGGCTGGAGTACAGTGGTGCCATCATAGCTCACTAACCTCTAACTCA AGGCTCAAGGAATCCTCCTGCCTCAGCCTAAGGAATCCTCCTGCCTCAGCCTCCCGAGTA GCTGGGACTACAAGTGTGTGCCACCATGCTCAGCTTATTTTTCATTTTTTATTTTCCAAG ACGGGGTCTTACTATGTTGCCCAGGCTGGTCAGGACTGTTGATTACATATGACAGAAACC CAACCACCTCTAGTTCCCACCACCTTTCAACCTGCTCTTCCCTGGGTCTTCCCAGTCTCC GTAAATGGCAGCTCCATCCTTCAAGTTGCCGAAGCCCCAAATCTCAATGTTAACCTTGAT TTCTCTCTTTTATCTCACAGGCAATCTGAAGGCAAATCCTGTTTAGACCCAGGCGAAGGT TCCTGGTGACCCAGGCTCTCACCAGCCAATTGTCCCTTGCCGTCCTCCTGAGGGTATCTG GAGCTTCAGTGCTGTGTGCTCTTGGCCTCCACACTGGGGATGCCACTGACTCCCACTGTC CAGGGCTTCCAGTGGACTCTCCGAGGCCCTGATGTAGAAACTTCCCCATTCGGTGCACCA AGAGCAGCCTCACATGGTGTGGGCCGACATCAAGAGCTGCGAGATCCAACAGGTAAAAAT CCCGAGGCATTGCCAGCTCGGTGGGGTCAGAGAGTCCTCTTTCTATTATAACTCAGATGT GAAGGGAAGATGTCAAGGTCCCTAAACATTGCAGGGCCTTGCCTGGCATGAAACAGATAT TAAATACGTATTTGTTAAATGAATGAACAAATATCCACAGCCTGTGCCGCCCATGGCCTG CAGTGCCGTGGTCAGGTGGAAGTGATTTTACTTCAGGAGAGGACAGTGTTCTCTCCAGGA CTTTTCCTTACTAGCTAGATCTGCATCCCTCTCCCCGCTCTTCCCCTCTCACCCCCCATT CTCTGCCCCCATTTCTCTCTGTTTCCACCCTACTGTCCCCTTTCACCTGCTTTCTGCTCT TCAGCTTTGATGGCTCACCCCCTCCCTGTCCACCTGCATCCCCCAGGCTAAGGCTCCTAC ACTGTCCTGGGTGGGGAGATGTGTCTCGTTTTAGGCAGTGCCCTCTGGATGTGTCTAGGA TGGGGAAACATGGCTCAGTTGCCAGTATAATGGGTTAAAAGTGGCCACTTTTGAAGGCCT TTCCCACCTCCCATTCCAGAATCCTGTAGGACTTAGAATTTATGGGCCACAGTGGAATTC TTGGTTTCCCAGGACCTTGTGGTGGACACCTTCTTTCACTGAGCATTCATGGGGTGACTA TTAGGTACCAGGCCCTGCTCTGGGCTAGAGGCCCCACAATGAGTAAATCTCAGGTCAGTA CCCCACGGAACCCACCACTGCAGGCATTGAGAGGGGGAGAAAGAAAGGGGCATGGCCCGT TTGTGTTCTCCTCATGTGGTCGCCCACAGGTCCTGGGGGAGTAGGAGCCAGTGCAAGGAG AGAAGTCCAGTGAGAAAGGCAAATGGATGACATCAGACCCAGGGGCTGAGGTCCCCAGCT GCAGCTGGGTAGCTTCTGGAGTGGACAGGGAGCAACAGGGAAGTTCGTGGCCTGGTGTTC TGGGATGCATTGTCTCATCTCGTTCTTGTGAGCACCAGAACTTATCCAAAGACAAGACTC AGTGTCTCTGGCAACAGTGGGCCAGAGACAGAATGTGTGAATTTCAGAGGAGGAGGAAGG GGTTGTACCCCATGGAAACAGTATATGGTTTTACAGTAGCGCATCTTTCTCTAATAACTG GTTAGTGTGTTCCTGTTAATGGAAAATATTGGTGGTGTAAGTTTCCCCACTGTTCTCATC TTCATGTAAATTTGTTCATTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT TCCTTCCCTACTTCCCTCCAACTCTCTTTCTCTTTATTCTTTCCCTGCCTCCCTCCCACC CACCCTCCCTCCCTTTCTTCCTCCTTCCCTCCCTCCCTCCCTTCTTTCCTTTCTTCCTTT CTTCTTTTCCTTTCTCTCTCATGCTCTTTTTCTTTCCTTTTTGTTCTCTCTACTTTTTTG AAGAGATCACACTGTACTGAAACCTACATTATTTACCAAAATCTCCAGATCTGCTTCTGT CTTGCAGGCAGAGAGCTCATCCAGTAGCCCTTAGCTCTTCCCAGCCCCCTCCTTTGATTT GTGGGTGCCACTGGGGCAGCTGCTGAGTCTCAGTGGTTTCTAGTCTTCACCAAGTTCTGC CCACCCAGATGGTTTTTACCTCTCCTTACCAGAAACCTGCACTGTCTAGATTGCTGAGGC TGCTTCTCCTTAACCGATCTGCTATCTGTATTCCAGGGGCACCGCAGGGTTAGAGGTAAA TGGCACAGGCCTTGAAATCTCCAACTGCTCTGACTCCAGGTTGGTGCACTTCAATGCCAA GTACTAACCACCCAGTTACAGGATGCCACCAAAACCTTGATATGGGGCTGCTGCATCCTA ATTAAAACAAATTAATAGAATTTTTTTTAGAACAGTTCTAGGTTTGTGGAAAACTTGAGT GGATAGTACAGAGGGTTCTCCTAGGCTCCCCTGTCCTCCACACAATTTCTCCTATTAGTA TGTTTTATGAGTGTGGTCCATTGGTTACAATTGATGAACCACTGTTGATACATCATTATC CCCTAAAGTCCATAGTTTACATTAGAGTTCATTCTTTGAGTTTCACAGATTATGGGTTTT GGCAATTACATAATGTCCTAAATCCCCAATACAGCGTCATGCGAAATAGTTTCACTGCTG AAAATTCCCTGTGCGTCACCATTTCATGCGTCCTCCTCTCCTCCACCCCTGACAACCACT CATCATTTTACTGCTTCTTTTTGACTTTCCAAGAATGTCCTAGAGTTGGAATGGTACAGG ATGTGGGTTTCCAGACTGGCTTCTTTCTAGCATTATGTACTTTAAGTTCCTCCATGTCTT TTCATGGCTTGATAGCTTGTTTTTTAAAATCAGTGAATCATATTTCGTTGTATGGCTACA ACAGTTTCTTTATTCATTCACTTGGTGAAAGACATCTTGGGTACTTCCAAGTTTTGGCAA TTATGAATAAAATTGCTGTAAGTACTTCTGTGCAGGATTTTGAGTGAACTTGTTTTCCAA AGTGACAGTACCCTTTTGATTTCCACTAGCGATGGAAAGTTCTGGTTGCTCCTCATCTTT GACAGCATTTGGTGTGTTCACCTTTTTGAATTTTAGCCATTCTAATACAGTGATATCTCA TTGTTGTTTTAATATGCAATTCCCTAACGACAAATGATTTTGAGTGTCTTTTTCATATGC ATATTTGCCATCTGTATATCTTATTAATGAGGTGTTCAGATCTTTCACCTATTTTTTTTT CTTTGTGTTGTTTAGTTCTCAGAATTCTTCATATATTTTGGACAGCAGTTTTTCCATCAG ATTATTTTGTAAATATTTTCTGCCAGTCTGTGACTTGCTTTTTCCATTCTCTTGACAGTG TCTTTCACAGAGCAGAAGTTTTTAATTTTAATGAGGCTCAACTTAATTTTTTTCATTAGT AGATTGTGCTTTTGGTTTTGTATCTAAGAAGCCATCATCCAACCCAAGATCCCCAAGATT TTCTCTTATGTTATCTCCTAGGATTCTTATGGTTTTGCATCTTACATTTACATGTAAGAT TTATTTTATAAAGGGTATAACATGCATACCTGGATTTATTATTATTTTTTTTTTTTGCAT GTGTTTGTCCAGCTGTTCTAGCACCACTAGTTGGAAAGGCTGTCTTTGCTGTTTTAAATT GTCTCTAAACCTTCATGGACGATCAGTGGACTGTCTGTAGGCCTGTTTCTGGGCTCTGTA TTCCTTTTCCACGAATCTATTTGTGTGTGTTTTCTCTTTTCACCAACTTCACACTATTTG GGTTACTGTAGCTTAATGTAAGTCCTGAAGTTGATAGTGCCAGACGTCAGGGGGGTTTTC GGAACTTCATCATGAGAACCTGGTTGAGACCATTGTAGTAAAACTTGGAAACGTGTGAGA TTCCCCCTTAGTCTGGTTTTCAAGGAGTTTTTAATGCTCTAGCCAGGCCACCCTCAGCTT CTAGTAATCTGTCAATACCATTTAAGTGCTCCTCCCACTTGCTGTCCCCAGTAGCTTCTC TTCCCTGTGAGCTCTGACTCCTTGTGTGTTAGCCTGTCTTTCTCATTTTTAGGGTGGCCG TTTTCCCTGTGACCTCAATTCTCTGGTCCACCCTAGAAGGGTTGACTTTCAGTTTGTTCA GCTTTTTTCTAGCTGTGAGGACAAGTGATGACTGCCTAGCTCTTTCCATGTTGGAATAGA AACCCAAAAGTTCGTTTAAAGAATTACTTGTTATAAAAGTCAGCCATTGTCCACGTACAA CTCAATGACTTAAGGTGATATATAGAATTGTGCAGCCATCAGCAGAGTTCTACTTTAGCA CATTTTATCGCTTCCCCAAATTCCCTTGAACCTCTTTGTAGTCATTTCCTAATCCCTGGT CCCCATGACTGGGTCTGAATAGAATAAATATTTGGAAAGCAGACTTCATTATATTTACAT TTTCATGTGTTTGGGACTTTATATAGTGGACTATTGTGTTTGTTTTGTGACAAGCAGAGA AGAGATTGCATTCTAGGGATGTTTTTTGGGGAACATAACAGTAGTCTTGTTTATGGCTCT CCTTGAAATTGGTTCATCTGTGCTGGTGACTGGTATTTGCTACCAAACCTTGTCTGGTGA GCACAAGAAAATGAATTTTTAAAAATCTGCTATGAAAATCGAGATGATACATTTTCACAT AATAATATGTGGAGTTAAGTAACGAACCATCTTTATTTATTTATTTATTTATTTATTTTT TGAGATGGAGATTTTGCTCTGTTCCTCAGGCTGGAATGTAATGGCGTGATCTAGCTCACT GCAACCTCCACCTCCTGAGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGCGA TTACAGGCACCTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACATGGTTTC TCCATGTTGGCCAGGTTGGTCTCTAACTCTTGACCTCAAGTGATCCACCTGCCTTAGCCT CCCAAAGTGCTAGGATTACAGACATGAACCACGGCCTGACCTGAACCATTTTTATTCTTT CAGAAATGTGATTGATAACAGTAAAGCCACACTCCTCGCATGCCTGAAATACCCCTCATT GTCTTCTTCAGGTGGCAAGGGCTCTGAAACAGCCACATAAAGTTGAGGGCAATATTTTTA CTGTAGTTCTTTCATTGATTGATTGATTGATTGATGGATTGATTGATTTTTTCTCTGAGA GGAATTAGCATCCATGTATCTGAAATTGAAATTCAAGAGGAGAGACAGGCACCTGTACTA GTTTTCTCTTGCTGCCAATTATCACATTACCACAAACCAGTGGTTTGAAACCACAGAAGT CTGGAATGAAGCGGCTGGGTTCTCTGATCAGAGTCATGTGAGGCTAAAATTCAGAAATGG GCTGGCTGTGTTTTTTTTCTAGAGCTCAAGCTATTTTTCCAAGTTCACTACAGATATTGA AAGAGTTCCTATTCTTGTTTGTGGGGGACTGAGGGCCCTTTGTCTTTGCTGACTGTCAGC CAGGAGACACTCTGACTCCAGAGGCAACCTGCTTTCCTCCTTACCTGTCTTTTCCATCAT CAACCAATAACAACTCATGGAGTCCTTCTCAAGCTCCTGCCTTCTGTGGCTTCATCTTCT CCAACCAGCCACAGAAAGCTCTGTCATGTATGGAGTGGTGTGATTAGATCCAGTTCATGC AGGTAACCTCACCAGCTCAAAGTCATATAACTGGCATATAACATCATAATCACAGGAATG CTGTCTCATCACCTTAACAGGCTTTAGAGACAAGGGTGTGACATATGTGGGGACCATTTC AGAAATTCCATCTACCACAGTAGGACACTCACATTCCCCCAACTGCAAAATGCATTCACC GTCTCCCCTAAGGTTCCCAAATTTCATGTCATTTAAAGCATTAGTTCAACATGAAAAATG TCATGTAGATCACATCAGATCAAAAGTTTAAAATTCCATCTAAAACATCCACACCAGGTG TGGTGAGGCTTCTGAGGGTGTCCACAAAGTACAGGTCTTTGACATAATTCCCTTACCTCC GTCGACCTGTGAAACTGAACAAACAGCTTATCTGCCCCTAACGTGAAATGACGGGACAGA CATAGAATAACAGCTACAGTGATTCTAGTTCAAAATGAGGGAACATGGAAGGGATAAAGA AGTCAATGACCCAAAATAGTTTGGAAATGGAACTGGGCAAAATCCAGCAGAAGTTTCTTA ATTAGGATCGACAGCCTGGGACCGGCCCGCCGTCCTATGGGTCTTTGCCTCTGGGCTCCC TGCTCTGCATTTCTTGAAACCATTATTATTTATCTTTTTTCTCACACTCTTTTGCATATG GCTTCTGTTGCACTCAAAATGTTTTTGAGATTCATCCATGTTGTTTTATGTGTCAACAGT TTGTTCCTTTAGCCATTCCATGGAATGAATGTATCACAGTTTATTGGTCCATTCTTGTAT TGACAGATACTTGAATGTTTCCAGTTTTTCATATTATGAATAAAACTGCTATGAACATTC TTGTATAAATCATTTTCTGGACATATGTTTTAGTTTCTCTTGGATAAATGCTTAGGAATG ACTGAGTCATAGAATAGGCAGTTGTTTGGTTCTGTAAGAATATGCCAGATATTTTCCCCA AAGTGTTTATACTATTGTACATTCCATGCATTAATGTACGAAGATGAGAAAGCTTTTGCC CCTTCCAAAGAGGCCTGTCTATATACATGTAATTTTTTCTAACTGGAGACAGGCTGATGA CTTCAGGGACATGAACATGGGATACAGGACACCTGTCATCACCACCACCATGAAGTTGGG ATTCAGGAAGGAGGTTAATCATATAAGGAATCCTGTGACCAGCATGAGCTTCTGTCAGGC CACAAAGGGCACTCAAGTGAACAGGGCATAGTGGGTCCTGGGGTCATGGTGAGAAAGTGT CTCTTTGGTAAAACCTTTTCCCTTGGGGAGGTAAATAAATTCTTGGTTCCTTCTTGGTAG CCCTTGTAGATAAGGATGGTCAAATAAAATAATATTATATCTGTAAAAACTCAGATCTTG GTAAGATTTACTAGTTGGGAATCCAGTGTTAATGCCATGAAGCAGCCGCCAGTTGGGATC AAATGTGAGCCTATGGATCAAGGTGCATACTCAAACACAGAGAGCTTTTTTGAAAGATGC CACCAGTAGTTTTTCCAGGGCAGAGATGGGTCGTTTATTTCTCTCTCTAATCTAGCCCAT ATGCTAGCTGAGAAGGTTTCTTCATATCACTTTAAATGATGATGTCCTTGTACAACAATT TTCTAAACATTCTTTAGATAAGAATTTAATGGGCATTCTTTATTGCATTAGGCTTAAATT TCATGCATCTTAAGGTTTTATTGCAAAGTGTTGCCTTGCTTCCTTTTTAAGATGATACAA TTTATAACACGCAAGTTTGCTGTCTGTCCCCTCCCTTTATATACATATAAAATGAGCAAA CATGTGGCCATGAAACAGATGGTCATAGAATTGGTTCAGTGGTTGTGAGTTCAGCAACCC AAGAGTGTCTTATCTGAAATACCACGAGGAATGCCTGGACACAGTAGACAAAGGTTGTTC AACTGGATGCCTTAGGATACATGCTACCAAAAACAAAGTAGCTGAAAAGGAACCAGAATA ACAGAATATCAGAGCCAGAGGAACATTTGGAGGTAATTCAGTACCTCCTCCTTTTCAACC TACAGGGGAGATAGTGGAACAGAAGCAGAAATGGGCCTGCCTGCTGTGCCCAAAATTCAT TGGAGATTATTGCGGTGAAGAATTTCATTTATGATGAAGGAGAATTAAATCCCCGTCAGT TTAAATTCAGGCAGGTTTATTGAAAAGGTGAAGAAGCGTCTTGCAGAAGCAAAGCGTGGC TGAGGCTTGTGGGCTTTGGGAAAATGAGCAGCTGACAGTGGCTGATGCTGCCCCTGACTC TGGGACCATGTGGTCTCTTGTTCCCTGAGAGCATCTCTTCTATTCTCTTGCATCTTCCCT CAGCCTGGCAGTCTCTGTATAATCTTCAACACATAATCGAGCAAGGCTGTGCCAGCCCCA ATGCCACCTGGCACTTTAGGTCAAATTAGGAAGGCATGAAATAAACTGGCCCTTTATAAT ACAGCTGTTGGAACCACAGTTGAAAGTACAATATCTTGACTCCTGGGTTAGTGCTTTATG CTGAGCTTTTTTTTCTGAATATGAGCACAGACTTTGGAATATTAGTGTCACCTAGCGTTA TTAGCTAGTATTCTCCTTTTGTTTCCCCATGACATCCCCTCCTTCTTCCCACAGATCCAC TGTCCGCTCATTTCCATCCTGTCTCATGCCACTCGGGGCTCGTCCCTTCTAGAATGCATT CCTGGCTCCCCTGCATGCACACTTCCAGTTAGGTTTAGCAATGGAGGGCACCTGATGGAG CCTGGAAGTGAGAGGAAGGTGAGGTCTGTATTTCTTCCCTCTCCCTCCCTGCTCTGGCAC TGAGTATCTGGCAATAGCTGCATCTGTCTATTACTTCAGTGGCCACTCTTCCACAGCCCC AGTTCTCAGTGGGTCCCATAGCATTATTTACCTTTGTTCCTTTAGCTCCCATCAAGGAAG ATCCAGAGACATTCTCCTTACCAAGACGTTAAGAAATGCACAGGTGAGGAGAACAGCGGC ATGCGTGTAAAGGTCCTGTGGCACCCATCCTCTGCAGGCTGGAGGTCATGGCGGGAGATG CTGCATGGATTTGCCCTCCCCGCTGTCAGTGAGAACAACAGGGTTCTGGAAGAGTAGAGG ACAGGCCATGGGACTTGGCCATCTAGAGATAAGGCGGGAGGGATTTCCTTGAGAGGCAGG GATATGTGGTGGTTACTAATCATTCGAATCATTGTGAGGTGTCTGGGAATGTAATGGATG GGAAATCTACTAAGAAATCAACTTAGTAATAATTAGAAAAGCTCTAGTTCTGAGGACAGA GACCTGATGGAGTCACCATAGTGGGAATTTATGACCTGGCATCCGGTTCAGATACCTGGA GCTTCTTGAGTGAGGGAAGATTGGATCCCTTGAGGAAGAGTGAAGCCTTCAATGCTGCCA CCAGTGTATGCTGTAAATCTTCCTCCAGGCCTTCCCCAGAAGGCCCTGAAGCCATTTATG TGGGTGACTGAGGAAAGGGAAATACTCAGAGCTTCTGTGGCTTGTTGGATTCTGGCTCTG AAGAATGCTAAACTAAGGGCACCTGTGGTGGCCATGAAAATGCACTACTTGCATCTCCAG CTGCAGGAGGCCTAACGAATCAGCAGCCCCAGCTGCTACACTCCGAATGGAGGACTTGAT GACATTTCCCCTGGATCTGCACTAGCCCATGAGGAGGAAAGCCTCCTATCAAGTCCTCCC AGCAGAACACCCATGATGACTCATGAGGATGTTGAAAGTGTTTTCCTGTGTCAACTGTGA CTTTCTTTCTTCAAAGTCTGTTTTGTTCCTGCACATTAACTGATTTATATCAAATAAGAG AATAAATGCCTAGACTCCCATGAGTCTATCTTTTACTGATAAACTCAATAGTTCTGAGGA CGGAAGCCTGATGGAGTCAGTATAGGGGGAATTTATAACCTGGCATCCAGTTCAGAGACT TGGAGCTTCTTGACTGAGGGGAGATCGGGTCCCTTTGGGGAAGAAGGAAGCCTTCAATGT TGTCACAAGTGTATCCTGGAAATCTTCCTCTAAGCCTTCCTAGAGAGACCTGATAATATG ACTTATGATACAGTGACCCCAAATTCAGGGTGTTCTTGTCTACTCTCAAGAATGCAATAT CTTCTTCCTCTGAATTGAACGTAGTACCAATATTTGTGTGTAGCTATGCACCTTAATAGA CCATAGCTAATTAGATGAGGAATGGTAGACCCAATTCAACCATACAGGCGTCAACCATAT CAGCATACAGGCATCCCTCTCCCACCGTTTCCTTCTTGTCCCCACTCCAAAGCCTTCTCC ATTTTATTTGTATTAACTTTCTATTGCTGCATACTAAATTACTGCAAGCATTAGCGGCGT AAAATAAGAATGATTTATTTTCTTGCAGTGTCCACAGATCAGAAGTTCAGGCCTGGATTC GCTGGGTCTTCTTCTCAGGGCCTCACAGGCTGAAATTAGGCTGGGTTTCTTTCTGGAGGT TCTGGGGAAGAACATCCTCTCAAGTTTCCTCAGGTTGTCAGCTGAGTTCAGTTCCTTGTG ACTGTAGGACTGAGATCTCTGTTTTCTTGCTGGCTGTCAGCCAGGGGCCTCTCGCTGCTC CTAGAGGCCTCCCATGTTCCCACTGCATGCTTCCTCCAGCCAGCAGAGGAGGATCGCCCT GCATGGAAACCCTCCTGCACTTCACATCTCTCCAGGAAGTCCTCAGTCCCTCCAAGGAAC TCACCTTCACTAGGTCAAGCTCATCAGATAATCTGTCTATCTTAAATTTGACCGATTTGG GATCTCGATTACATCTGTTAACTTGTTTTTGCCATAAATTGTAACACAATCGCAGGAGTG ACATCTCCTCAGTGGCTTTGTCTACACTCAGGAAGAAGTGATTATATAAGAGCAAAGATC ACTGAGGGTCATCTTAGGATTCTGTCTACCATAATATTATAAAGACACAGTAATTAAAAG AGTATAACAGATTTCTGCTTCTGTCTGTTAGAATAAATCATATCAGACTAACCCTGCCTC CATAAACAACCGTAAAATTGTTTTCAGCAGTGTACGACAGGCAGTACAACAGAAAACTTA AGGGGGAAGCCCCATGATTTCCTAGTTCTTTGGGGAGAATTTCTCAGCAGCTGCATAGTG GGCTAGAGTCCACTCAGGGCAGGGCAGCCCACTGAGCTGAGAAGGCAGAGATCAGAGTTC AAGACCATTGAAGCAACTGCAATCTGCAGGGCAGGGCACCAATGAGGAGACAGCTGATCA AAGGTGCAGCTCTCAAAGTCTATGTGGGGTTCCATATGCATCCTTATCAAGGACTGGACT GTACCTGCACAAGGAAAAGACTAACAGATTTAACAGAGGGGTGGCTGCTATAAAATTGAG TTTGGACCAGAGGTACTTGAGGCGGAGGAGGGTTGGGGAATGTATGATGGAGTTTCTGCC ATCCACGGTGGGAAGAACTCATGCACACCTCATTAGCACCCAGGTATCCAACTGAGACAC TAGAATGGATGTGCTTTAGGAATAAGTGTCACACTTTTCAATAAGGCCTATTGTTCACCA ACCTGGTAAAGCCTAAAGCCAAACCCTGACAAAATCCACAAAGGGGTGGATTGGTGATTG AGTCCTGCCAAATTAGAGGGTCTTGGGAAATTCTGTGGGCTTTCCATGAATCCGTTGTAA TAAAACATAAACCAGTCCACATAAGTCCAAAGTGATCGATCAGACAGTAATTTTACGCCC ACTAGAGCAAAATTAATTCACACAATCAATGACACAAGTTAGCCAAGTCGACATTTAAGC AAAATACATCTAAGAACAGCTAACAAATAACTCTCCTCAAACTCACATAGAGCATTCACC AAGATAGACCACATATGCTGAGCCATCCTTAGTATTTTCTGTCCTTTCTCTTTGACTCGT GTATACTGTGCTCAAACTCTTAAAATTATACACTTTAATTATATACTTTAATGATTATAC ACTTTCATGCATCTCAATTGCATGTAAGTTATATTTCAATATATTTGTTAAAAGTTTATA ATTAAAAAAACTGTCCTAGCTTGATTCCAGAAATCTTTTTTATATTTTAGAAAATGTAAT GTTATATATTATCAGGGCAAAAGAGAAAAACCGTATGATTACCTTGTCATACACAGTAAA AGCATTTGGCAAAATTGAAAAATTTTTCATGATTTATAAAAACAAACCCCAGAAAACTCA GCATGATAAGAAGAGAAGGCAACACTTCCAACCCTATTAAGGGTAGATTTGAAAAAAACT CACAGGTAACATTATATTAAATGGCATGGGATTGAATGCTTTTCTATTAAATCAGATAAA AAAGTAGAATATCTGTTGTTATTCTTTCAATTCAGCATTATACTAGAGATCTAAATCAGT GCAATAAAGTAAGAAAAATAAAAGTATTGAAAAGATTGAAAAGAAAGAATTGAGGCTGTC TTTATTCACAGATAATGACTGTGTATGTTAATAATCCTAGAAATCTGCAAAAATCTGCCA AAGCTAATTAGTGAGTTTGGTAATGTTGCAGAGTATAAGCTCAATAGAAGTAGTCTTTTG TATTTCTGTGTATTAGCAATGAGCATTTGGAAAATGAAATAAAAATACAATTTCATTTCA AGTAACTTCTAAATACATGTGCTTATAAATAAATTCAACAGGCTGGGTCTGGTGGCTCAC GTGTGTGTGTGTGTGTGTGTGTATGTATGTGTGTGGGTGGGTGTGGGTGTGTATATTCAC CTTTTTGAAGATTATCTATCGTTATCTCCAAACAGGGAACATTAAGAGAACATAAAAAGA AACCACAATATAGGAGATATCATATTTATTTCCAACAAAGGGTTTTTAGAGTGTGTGTGT GTATATATATATATATGTATGTATATATATGTATGTATATATATGTATGTATATATATGC ATGTGTATATATATGTGTGTTTATATATGTCTAATAAGAAACAACACAATGAAACAATTT CTCAAAAGACTTGAATAGATACTTCAGTAAAGAAGATACATAAATGGTCAATTAGCATAG GAAAAGATGCTCTACTGTTTAGTCATCAGGGAGATCAATGAATACAACTTGATAGCAGTA CATATCCAAGAGGATGGCTAAAATTAAAAAGGCTGAAAATAGCACATGTTGGTGAGGATA TAAAGCACTTGGAAGTCTTATACTTGGAATGAAAAATGGTAGGACTCCTTTGAAAATCTA ACAATGTCTTAAAGGTTAAACATATGCAAATCAGATGGACAGTCTTCCATTCCTAGGAAT GTACACACTATGTGTGCACATGATCTGTATGTGTATTTCCAGACCAGACTGAGGGGTGGA CTGCTATTTCTTGTGGCCCAGTAACGAGATGCAGATGAACTGGGGAGGAAGAGAGTTTTT ACTTCTGCAACTGATTACAGGGAAAAGGCCTGGAAATTATCACCAGACCAAGTCAAAATT ACAAAGTTTTCCTGAGCTTATATACCTTCTAAGCTATATGTGTATGTGGAAGTGTGCATT CATCTAAATACAGAAGTGATTAAGTTCTTCTAATCTATAACTAAGGTCTGAGTCCTGAAG ACCTTCCTCTGGAGCCTCAGTAAATTCACTTAATCTAAATGGGTCTAGGTGCTGGGCACC CTTATCTTGTCTCCTGCTAAATCACAGAGGTTTGGGGAGTTCCTTCAGACCTCCAATAAA CTTGTTTGTGGAGGCCTGGGGAGTTTCTTCAGACCCCCAATAAAACTTGTTTAATACTAA ATGACTCCTGTTAAGAATGTCTTCGTTATTTTGTCATGCTTTAAGGCCCAGGAAAAGCCC AGGCAAAGCTCTTGGTGGGCTTTGGTTACATTCCAGCCTTTGTAATAAGGGCATGGGCTT TTTTTTTTTTTTTTTCCTCTTAATATTTAACTGAACCACTCAGTCGGTACTGAAACAGTT GTTAGGGAGGCCTGTGTTAGTGAGACCTGGCCTGCCACGTATGGATGCTCATGATAGTTT CTTCATAATAGCCCAAACGTGGAATGATAGAAATGTCCAATAACAAGTGAAAGTATGAAC AAACACAGTATAGCCACACAAAGGAATACTACTCAGCAATTACAAGGCATTAACCGTTGA TGCAAATACTCATATGGATGGATTTTAAAATTATGTTGATGCATGAAAGAAGGCAGACAC AAAAGAATACGGGTACAATTTCATTTATAGAAAATGGTTAAAAATGGAAACAGACCTGAA GTGACAGCGGCTCCTTGAGGCCGAGGGCTGAAAGACTGATGAACTGCAAAGGGGTACAAG AAACTTTGGGGCGTAGGGAAATTCCTCTATCTTGGTTGTGGCAGTAGTTCCATTAGTGTA TACATTTGTAAACATGCATTGAATTACACATTTTAAAGTGGTGCAGTCTGTTGTACCTAA ATGATGCCTTTATAACATTGATTTCATCATCTTAATTTCTCCATACTAGCAATTAGCAGC TAGAAAATGAAATTCAGTAAAACATAATCGAGATTAATAGTCAGAATCATTACATGCTTA AGAATACATGCAATGAAGCGGGTACAAGGCCCGTAAAAGCAATTGGTGAGAAAAATTAAA GAAGACTAAATAGAGAAATATATATCATGTTCATTGATTGGAAGATTCAATTTTGTTAGC ATATTACCTCAACAGAATTCTGATTAATATTTCTAGTAGGAGATTTTAGAGAAATGTAAA AGCTAATTTCAAAATATATTTGAAAATCCAAGAACCTAGAATAGGCAAGTCGGTCTTGAA GAAGCAGTAAGTTGGAGGACTTACTCTGCTAGACTTCAAACCTGATTTAAAAGCTACAGT AATTTAAAATGGTAGTACTGGTGTAAGTATTCATAAATATATCAAAGTAAAAGAATACAG ATTCAAACAATATGACCACATATGTAGTTATTTATTTTAGTAGAATCTTTTTTATTCATA AAAAATCCCTCCAAAACGTTTTCCAAGAACACACAGGAGGGCTATGGGTAGAGGAAGGTG TCTGTCCATCTATCCCTGGCCCCCAGCCCATGTGGTTTTGGCAGCAATAGGGGTGTGGGG TAATGTCCCCCAAAATTAAAATGGTATATGTGTGTATGAGAAGGAAAGGGGGGCAAAGCT GTGGGGAACGGTTGAGGGGAAGGAACAAAGGAGGTCAGTACTGGGAACGCTGAAGATGGG AGGCCATTTCATAACATTTCTTGTTGATGAAACTGCCATGGACAGCTTCTTTGCTCATCA GCAGGCCCAGTGTCTTGGCAATCATGGTGACAGTGACATTGAAGGTGGGGGCTCCACCGA TGCTCTTCGTTTGAAGATGCACGGTCAGTTCCCCATCCTGCAGCAGTGAGTCCAGGACCA CAGTACATTTCTGGCCCCGCAGTGTCAGCCTATTCACGAAAAAGCTTGACCAGTCTTTGC CAACCAGGACACCAACCTTAGCTGGCGTGATGTTCACGAAGGTTTTTCCCTGGGACGGCG GCCCAGATGGAGGGTGAGTCCTTGTTGCCCACGATGGCCGCGAACCTAACAGGTCCCATC CGCCACGAGGCTGTAGATAGAGGCGTCCACCTGGCCGTTGCGCGGCTGCGGGGGCTCCTC TGGTCGCTGCTGCTGGGGCCGCCTGGGCTGGCGGGCAGGGGAGGCGGAGAGCTGCGTGCA GGCACTGCCGTCCTCACCACGGCTCTGCTGGCTGTGCAGTGGCCCTCGCACCGCCATATA TATATATTTATTATACTTTAAGTTCTAGGATACTTGTGCACAACGTGCAGGTTTGTTACA TAGGTGTACATGTGCCATGTTGGTTTGCTGCACCCATTAACTCGTCATTTACATTCGGTA TTTCTCCTAATGCTATCCCTCCTCCAGCCCCCAACCCCAGGGACAGGCCGTGGTGTGTGA TGTTCCCCGCCCTGTGTCCAAGTGTTCTCATTGTTCAGTTCCCATCCATGAGTGAGAACG TGCTCACGCTGCTACTTCTAAATGTTTTAAAAACAAAGACACCAATGCTCTTCATTGAGG AAATGGAAGACTTTTAAGTAAAAGGATTTTGAGTGAAATAATATTTGTGGTTTTAAAAAG TTAATATTAACCACTCTTCATCATACACTGAAATTAACTTAAGATGTGAAAGTTAAAATT AGAAACCTTGTAAAGGAAAAATAGGAACTAATTTCGTGGACTTGACACAGGAAAATGTTT CTTAGACTAGATACTGTAACACTCACCACAATAAGAAATCAAGCAAATTGCCCTTCATTT TTAAAAACCTTCTGCTTATTATGTTGTTGTTTAACAACTTAAAAGCTATCTGTAGACCAG GAATAGCAAATAATTATTTGCTATATAATATAGCAAAAAATGTGTATATATAAATGGATG CATTCAAAATATATAAAGAACTCCTATAGGTTACAAGAAAATGACAAACACACCAGTGTT TCAATGAACATAAAATTTTGAGAAGATATTTTCCATAAGAAGATATCTTACTGAACATTA GGCATGAGAAAACCAAAACAGGATATCACTACCCACCTAGTAGAATGGCTATAATTTAAA AGACTGAAAATATTAAGTGTGTGGGAATGTAGAGCAACTGGAAATGGCCTACATCTTTCA TAGAAATGTAAAATAATACAATGACTTTGCAAAGCTCTGTGTCCATTTTCTTCCCATTCA CCAAGCAACTCCATCCGTAGCTATAGAGACCCAGGAAAATCAGTATGTCCATTCACAGAA ATAATTATATGAGAATATTCATAGTTACTTACGCACAGTAGCCAACAAGTAAACCTGTCT CCCGTCAGAAAAATGGATATCAAATTGTGTGATAATCATACAAACAATAGGATATTACTT GGCCAAACAAAACGAAACAAGGGAAAAACACAGTCAAACAAATTAGTGGCATATATAAGC ACCTGAGTAGGAGAAGTCAAAACAAGAGGAAGTACTAAATGATTCCTTTTTTTAATTTTT TTGAGATGGAGTCTCACTCTGTCCCCCAGTCTGGAGTGCAGTGGCACGATCTCGGCTCTG CCTCCCAGGTTCAAAAAATTTTCCCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCA CCTGCCACCATGCCTGGCTAATTTTTTGTATTTTCAGTAGAGGCAGGGTTTTACCATGTT GGCCAGGCTGGTCTTGAACGCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTTGCAAAGT CTTGGGATTACAGGCATGAGCCACCAGGCCCAGCCAAAATGATTCCATGTTTATGAAGCA CATGATCAAGCAAAATGAATCTATGGTGGCTGCTAAGTTTAAATATTGGTCCCCTCCAAA TCACATGTTTAAATGTGGTCCCCAGTGTCGGAGGTGGGGGTAAATGGGAGGTGTTTGGGT CATGGGAGTGGATCCCTCATGAATAGATGAATCCCCACCCTGGGAGAAGGTAGTGAGTGA ATTCTCACTCTCTTAGTTCCTGTAGGAGCTGGTTATTAAAAAGTGCCTCTCACCTTTCCT TGCTCTCTTTTGCTTCCTCTCTCGCCATATGATCTCTGCACACCCTGGTTCCTTTTCACC TTCTGCTGCAAGTGGAAGCAGCCTCAGGCCCTCATTAGGAGCAGATGCGGGGGCCATGCT TCTTGTACAGCCTGCAGAACTATGAGCAAAAGGCACCTCTTGTCTTGATAAATTACGCAG CCGCCGGTATTCCTTTCCAGCAACACAAAGGGGCTAAGGCGGTGACAACATTCAGAATAT ATTCTTCATTTGGGGAATGAGTATTGACTGGCAAGGACCACATCAGAACTCTGTGGCATG GGGGAAAATGTTCTCTGTCTTTAACTGGGTGTTACTTTACAATTATAATTATATTAAAAT TTATTAAGCTGTGCCTTTAGGTTTTTTGCAGTATACTCTATGCAAATTTTACCTCAGTGA AGAACTGTTAGCATACAACAGAGAGATAACAAACACTCAAAAATTGAAAATTGATGGAAA GTAGATAACAAATATTTAGCCTAGAAATAAGAGGGATCCATTGAGAAGAAACCAAAAGCA ATGGAATAGAACAAAGACAAAAAAGTATAATAAAAAGAGTTTTAAATTTCAAAGTTTGAA ATGATATTCAAGTGACACACTGTTTCCTTGGGAAAATCAAGTGAGAACCACAACTCTGAG ACTAATTCCAGCAAAAATATGTGAATCAGTTTGATCTAATGGTACAAGGTTAGCTTTGAA GGCCAAAAGGAACTGGTTTCTAATTCTTATTCCTCTCCTCACTAGTTTTGTGACCTAGGG AAATTTTGCAATCTTTCTGAGTTTGTTTTCTCATCAGGAACAGGATACTACCTAAGTAAC AGGATAGTTGATAGATTTAAATATGATCGCATGGCAGTGGACATGAGCCATAATTAGTTG CTAAGAATATATTGACACTGAACTCTCCTTTATCCATGTTAAAATTGTAGATAAACAACA ATTGACAAAGAATAGACAAAATATTCTAACATAAATATTCTTCCCTTGTTTCTAGAAAGA AGTCACACATACAGTAAAAATAATTAGAGAGGACCTAGTTCATATTGAGCAATCTTCCCC AAACCCTGAAACAGGTCTTCTTTCTAACACCAGAGGTATCTTGAGTGAGTCCAACCCCTG CAGTCCCCTCTGTCTGGAATAGATGGAGGAAGTTTGCTCCAGCCTTAGAACAGCATGGGC TGGCAAGCGTTCTCAGAGAGGTCTCGACTTCAACTCTAAAGGGCCTGAGGAATATGTGCA ACTGGGTCGGGTTAAGGCCAAGCTGAATCACATGACCAGGGCTCTCACCAGCGCCAAAGT CAGTGGAAGGATATCAGTCCCCAGAGCTCTGTCACAGGCCATGGATGCTCCATGGAGGGG TGGTGAGCATATGAATAAGAATCAGGAGAAACATCGGTAATGGACAGGAGGCATAAATAA ACAATGTCCACCGTCCTCTAAAACCCAGGAAAGTTCTCATTCAAAAGACGATGTCTTGAA GGAAACATAGGTACAAATCTTTGTGACTTTGGATTAGACATTTTTTAAGTAGGCACAAAC AACCGAAAAATAGATAAATGGACTTCATTAAAATAAAAAACTTATATGCTTCAAAGGACA CTGTCAAGGAAGTGAAAAGATAATCCACATAATGGGAGAACTATTTCCAAATTATATGTT TGACACAGGTCTAGTACCTAGAGTATATAAGGAATTCATATAACTGAGCAATAAACGACA ACCACATTTAACAATGGGGAAAAAAGCTGTGAGTAGAGGTTTCTCTAAAGGAAACACTCA AATGGCCAAGAAGCACATGCAAAGATGTTCAATGTTTTTCGTCATTAGGAAAATGTAAAT TTAAACCAAAATGAGATACCACTTCACACCCAGCAGTATGACTTAAGAAAAAAATAAAGA CAACACATGTTTCAAAAGTGATGGAGAATATCGAATTCTCATATATTACTATTGGGAATC TAAAATGATGTAGCTACTGAAGTTAGTAAACAGTGTGTGAGTTCCTCAAAAAGTTAAACA TAAAAAAAGTTAAACATAAAGTGACATATGATGCAGCAATTGCACTCCTAGGTTTATAAC CAAGAAAATGAAAAACAGGTGTTCACTCAAAAACCTGTACAAAGCTGTTCACAGCAGCAT TATTCATAATAGTTAAAAAGTGGAAACATCTTTAACCACCATCAGTTGATGAATAAACAA AATGTGGTATAACCATATAGTGGAATATTATCTGGCCATAAAAAGTTGAAGTACTGATGC AGGCTAGAAAGGATGAAACTTGAGAACAATATTCTAAGAAGCAGATAGAAAATACCACAC TTTGTTATTCCATATAGAGGAAGTGCCCAGAACAAGTACATCAATATATAGAGAAGGTAG ATTAGTGGTTGTCAGAGAGCACAAGAGGGGGGGAATTGGAGAGTGTCTGCCCATAGGTAC AGGCATGCTTTTTGGCATTATGAAAATATTCTGGAATTAGGTAGTGGCGATGGTTGTGAA AGTTTTGGAATATGGTAAAAGACACTGAAATGTATGCTTAAAAATGGTGAATTTTGTGAT GTATAAATTCTACTGTAGAAATAATAATAACAACAAAAGTAATAAAGCAAGGTGTCTTTC CACATCTCCATGTCCAGTATTTTCATTAAAAAAAAAAAAGAAAGTAAAAGCATTTCAGGG CCAGGTTCAGTGGCTAACTTCTGTAATCCCAGCACTTTTGGAGAACTAGGTGGAAGGATC GCTTGAGGCCAGAAGTTCAAAACCAGCCTGAGCAACATAGCAAGACCTTGTCTCTATGAA AAATAAAAAATTAGCCAGAAATGGTGATGTGTGCCTAGAGTTCCAACTACTTGGAAAGCT GAGGCAGGAGGATCGCTTGAGCCCAGAAGTTCAAGGTTGCCGTGATCTATAATCACCAGT GCACTCCAGCCTGGGTGACAGAATAAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAA AGCATCTCACTTTAATAGTAAGTGGCCAAAATATGATGCTGGCTGCATGTTGTGAGGAAA TGTGTTAGATGAAAGAAGTTAAATTCCAGAAGATTTCCTTTTTTCAGAAATGAGGTATAG GGGAGAGAAGCACTGGTCCACCTGAGATCTGGCTCCAGGACTTACAACAAGGGGAACTTG GGCAAGTTACAGACTCTGTGTGCCTCCATTTCTTCATCAGCAAAACAGAAAGAATCATCC CATAAACTGTAAGGTCAATGCTGTCAGTGAGTCCCCAAATTGACTGCACATCTGAGTCAT ATTAACAAACACATTCCAGGCCCCACCTGAGCCCTCTGAATCAGAATCCCTGCAAGGAGG ACAATGAACTTGTATTTGCACTGACTTTCCCAGCTGTTTCTTACTTTGATCAACTTGGGG GTGGGACCCATTGAGCTGCATCACATCATTCCAAAGCCAAAACACAACAGCAGAACAAGA ATATTTTCAATGCAGTCTCTGAAGCAGAGGAGAAACTTTTGAGGGAACCTAGAAGTAAAG GACATCTGGCTTGCTGGGCTCCATTTAAACTTTGAGTATAGCAGAGACACGAGCCCTTCG GGACACATGCCTGTCGCAGTGACACTCCAACTTCGGAAGAGTGGAAGCCCTAATTCCAAA TTCAAGCATGCTTTGAGTAGAAATGAAGTTTGCCTCTTTTTGCACAGGAAGATGGCCAAT CTTTCCTAAGCTGCTGACCTTACAAGAAAAAGAATCGTACTGCTAAGAATTCAAACTTCA GCAGTCATGGGTGAGTAAGGAAGTCTTATAAATGTATTTTAGCCACCTAACAAGAAACTA GAAATTTAGCAAGTTCTTTCACATTCAGGACAGTTGTGTTCACTAGATCAGAGGCACTGA GACATGAAGAACAGACCCCTAAAAAGGGAAAGTGTTCCTTTCAGTTTTAGGACACCACTG GAATATTAGGGAAGTGGAAACACAGCTGCCCACTCTACAGTATGGGTTGCCTTTGTGTCC GGAATGTGCCTAACGTCCTGACCTCCATGCCCTTTTCAGGGAGCCTTGGGAGGAGCCCGA ATCACTGATGGAATCGGACAGTGCATGGAGATGGTTCAGCAGGACGAGGGTAAGTGCAGG GGCAAGTCCAGGTCATACTGAGAGACAACGAGTGGCGCTGACAAGAGACAGACAAAGATA AAATCAAAAGTTTGTGCTTCATCTTCAAAAATCCAAACTAATAACACACTTGGCCTTATG AGAAATAATAAGTATTTTTCTATTTACATGAGAATTTAATCTCAAAACAGGAATCAGAAA TATATTAAGTCCAGGGCATAAAACCTAAACCACTGCTCATATTTATTCTTTCTAAATAGA GCAAAGTGTAAAATCTTCTCCATAAAATGCACATTGTGCTTATGAAAAGGCCAAAGTCTT AGTGAGAATCATTGGTATTCCATAGAAGAGTGAATTAAACACAGCCAAGGGAAGACCCAA GTCTCATACTTCTCTTGTATATTCCAGAGTTCCAGGGGAATTCCAGGTGATAGAGGTGAT CTCCCATACTGTTAAAGCAAGGTTGCAGACACTTGGGAATTTTGGTCCCAGTACTCTAGG AGGTCACACCTCTGTCCTGGACAATACTACAGGAATGTATACTCTTCCTATGACTCATTC TGGTCATTCTTCCAGCATCACAAAAACCAAAAAAAAAAAGGAAATATGTCCAAATACATG ATTTGCTATCCCTCCTCTTCAAGTTTCTTACCTGTTACTTACGGATAATAGCATTACCAC AGGATTATGATGAAGATACAATGTCCAAATGTAAGCACAGTTTTGAGCAAAATGCCTTGT ACGAATTGGTCAGTGAACAACTGGTAAATAATTATGTGAATATTTACTGAATTATATGGA TCCTATGAATAATTACTGAATAATTACTGTGATTGCTTTTATTGGCAGTGCTGAAAACTC ACCCCTGTGTGACCTCAAGTAAGCCACGTAACTCTGTGAACCTGCAGTTTTATCATTTTT AAAATAAAGAAACATGACAGATTTTCATTATGACACAGAATGTCAGGTCTCCCAGATGCC AGAAAATACATTTACTTAAAGCCGTTGATACGTCTTAAAGCGGTTTCCTTACAGTGTCAT TGGAGGACAGCGTGGAGTGCAGAGAGACATGCTTTGAAATGGGATTGATCCAGTCCTCCT TCCTTCACTACCACATGAATGCTGGGCAGCCCAGGATCACACTCACTGCACCCTCAACTC AGGCAAGTCCAGCAGCCAATCTTAGGAGACCTGGGCTACAGAACAGTCTCCCAAGTTCCA GGCTCACAAAACCTAGGTGGGGATGAAAGCTGAGAAAGTGAGGAGGTGGTTCAGGGGATC ACTCTTTCCTACTCATTCCTCTCATCTCAAACTCACCCTCTACTGCAACACTGAGGATCA CCAACCAACCGTGACCATAACCTTGATCTTGCCATGTTCTGTTAGTGGAATGAAACCAAA AATCAATGGTGTTAGTCCAACCCAACGAAATAGATATCAAACCACATTCCATAAGAACCG CCGCTCATGGCCCTGTTCTTTTCAGTATATGGGAAAACAAAATGGAAACAACAAAATAGC ATCAGGTTTATGAAACTTCCCAAGATAGATGGTCACACATGTGTTCAGGAGATCTCTATA TAAATGATTTTGGTCACTTGATACCTTGAAAAGAGCTCTTGTGATACTAGAATGACATCC ATAAGTGACGAGTATAAAATGTAGCGCTCAGTGACATCAAAAACCAAATCAACCCACATA GAGGAAGAGCTCTGGACATAGGGATGTCAAACTGGTCTAGAGTGTAATGAAAAGCAAAGA TGGTGCCCCAGTGAGAAAAAAGAAATCAACGTAACAATGGGAATCAGCAAGAAGAATACT GAGACAGGAAAGACAACATTTTTTACAAATGAGTTATTCATTCACTTTCTAGTGGATACA GACAAAACTGCAGAAGACCCAGAGGAAATCAGGGCAGGCTAAAAGTTTGATATCTTACAC TTGTGGAAAAGCCTTAAGATCTGTTTTAACTGAGAGCAGGTGGGGTGACTTCATGACTAC CGTTAAGAAAATATAACCTGTTGGGAAACTGGTTCTGCCTGGATGGTGTTGTACAAACAA GCGATAAACAATGAGGAATGTGCTTAGATGTATTGGGAAAGAGATGGGTCTGTGGCATTG TCACAAGGGTACACGAACACTGAGAGTGAATTTTAGAGGAATGATCCCCATTGGTGGTGA CCCTCAGGTGAGACGAGGGTGCCTGTGTTTCAGCAAAGCCTGGGCAATTGGAATGCAGGG CTCCTAAGATTCCATGACACCCCCACCTTCTAATTCTGTTATTGCAACTGCAGACCGTTA CCTGGCACACTGGCCTCACTCTTGTCGGAGACTGAGCTATTGGCAGTGCCTTCAGCTCTG AGCTCAGGCACCTCGAACATTGTTTTTGTCGTTAAGGATCCTAAAGTGCTGCGGGGACTG ATCACATTTTTCTCAACAGTAAGTTAAGAATTTCAGTTACTGACATCCCTCAGTCCTGAT TAAACCTATTTGATTTCACCAGTTTTTAACCCATCGTGTGTTTGGGTGTCTTCTCCCCAG TCCCTGGCCCCACCTCTTCTGCCACAAACGTCAGCATGGTGGTATCTGCCGGCCCTTGGT CCGGTGAGAAGGCAGAGATGAACATTCTAGAAATCAACAAGAAATCGCGCCCCCAGCTGG CAGAGAACAAACAGCAGTTCAGAAACCTCAAACAGAAATGTCTTGTAACTCAAGTGGCCT ACTTCCTGGCCAACCGGCAAAATAATTACGGTAAGTTCTATAGGCTCACCATCACAAAAG CGATGAATGATGTCCTGTCTTCTCGCTGAGAAACTAAATGCTCTCTCCATCAAAAATAAG TTCAACCCTCCCATACTTCTAGGAAAATAGAAATGGGCATTTTCACATTTTGTTAAATTG GGAAGTCAGAGGTACCAAAGTATTTAGCAACTTTCCATGTTTGCAGTCAGGTGGGGGTGG GCCTAGAGTTAAAATCGCAGTTATTCATTTGGGACACAGGCACAGAACGACCTGTTTTCT CCAAGAGGCTAAATCGTGTTTTCAAGAATCCTCTCTGTACCATATAAGATCCGGCAGACA AATAACATCTAGTCTGTTGTTCTAAATGTGTGGGACTAGTGAACCCTTATTGTGTTCAAG CTTCTGTTGAGGCCCAATAGGCAAAGCTCTGTTCTGGGGACCCTGAGGAAAACTTGGTGA TAGTACACAGTACCCGCTCTGAGGGGCTTCAAGGGGAGTCTGCTCCTAATAGAACCTGTG GTATCTGTAAGTGACAGCATCAAGAGCAGGGAGTAGGGGCCGTGCACGGTGGCTCACTCC TGTAATCCAAGCACTTTGGGAGGCTGAGGCGGGTAGAGCACGAGGTCAGGAGTTTGAGAC CAGCCTGGGCAACGTGGAGAAACCCCATCTCTTCTAAAAATACAAACATTAGCTGGGCGT GGTGGCGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCCCTTGCAT CCAGGAGGCAGAGGTTGCAGTGAGCCAAGAACACGCCATTGCACTCCAGCCTGGGCGATA GGGCAAGACTCGTCAAAAGAAAAGCAGAGAGTACCCGGTGAGAGGGAAGTCCTGCTTCCT GGGGCACAGGCTCTTGTTCCTAAAGAGGAAGAAGGATCGCACCCGAGATTGTGTGGAAGT AGCAGTGCAGTGTGCAGACCAGGGACTCTGGGCCTGTCTCCTGGGCTCCATCCAAGTTGC TTGTCTTGTCTGTCCCTCAGTTTCCTCATCTGTACATAGGGTACTACAGAAATACCTACC TCTGTAAATTGCTGCAATGAGTTACATGAGCTGTTTCTTGTCAATCTCCTAGAACTTTTA TTGGCACAGAGTTAACACTCTGTTAGTTCTTCATTCTACTGTTTCTAAATTAACACAAAC CTTAGTATTCGGGCAGATTTCCTTCATGGCCTTATGGTCTTACGTCTCATCCTTTATGCT TCAGATGTGATTCTTAAAATCACATCTAAAGCTATGATGTAAAAATCAAAGATGTTTAAG ATCTTTGACATATTTGTCCTTGAACTTCCCAGTGAAAGGGAAACCATCAGTCCCATAGTC CTAGGGGCCTTCCCAACTGTACAAGAAATCACTACTTCATGCCCCAGTGCAGTGCTTTAG AGGAGAGGCTGCAAGGCTTGGGAAAGTGGCCCCGCATTCAGAGTCAGACCTCAGGGGCTG TGAATTCTGACTCCACTTCATTGTGGTTGAATCATCTTGTCAACTTCCTTGATGTGCCTT GAGTTTCTCTTCGTCTCTAAATTTTGGAGGATCAGCTGCCAGTAAGTCGGGAGACTGAAG AGTAAAGATGTGGAAATCCCTACGTAGAGCCTGGCAGTGGGGACAGTTTTGTCCTTGGGA TGGACCTGGCTCCTGCCCTGTAGGCAGTGACCAGAGCAGCATGTCCAGCCTTTCACTGAG GCAGGCGTGTGTGTCTTTTCTCAGACTATGAAGACTGCAAAGACCTCATAAAATCTATGC TGAGGGATGAGCGGCTGCTCACAGAAGAGAAGCTTGCAGAGGAGCTCGGGCAAGCTGAGG AGCTCAGGTGAGTGGGCCCCCTGGGGTCAGGCAGGTGGGCAGGTGTGTAAATATCTGAAG TACAGCAGCTCGGCAGGGAGAACTAAGAGCTGAACTGGGCCAGGGGAAGGGCAGGAATTG CCATGGCAGGCTCACGACACACAAAGATTTATCAAGCAGAGAACAAGGATAATAATAAGT TATGGGTTGCAGTTGTTTTTCAGAGCCTTATTTTCTGTTTTTCAAACAAGTAATTGTTGA GGTGAAATGCGCATAACACAAAATTAACCGAAGGAGTGGGAACCACCGAGCAGCATTCGG CATACTCAAAGTGATGTGCCATCACCACCCCACTCACCCTTAGTCAGAATCAGCTCCTGA CTGACTGCGGCTTCTCATGCTTTCACTCAATGTTACCTTCTCGAGCCTGTCATTCCTTTC TTTCATCTTTTCAATTGGCCCCATCTGCACCTGGCCTCATTTCTGTCCATGGCTTTGTAT CTAGTCGCTGCAAGATGCACTATGTGTATATGCACGTGGAAATGTCCATGGCCAGAGTGA GGAACTGAAAGGATGGATGTCTTTTTGAAACTGAATGAGGAAGACACCTACTTTTGTTGA CAGAAGAGAAAGATGAATGGAACATCATGGAGGGTCTTCCAGGAGCCCTCTCTCATACAG AGGAAGCCTGTGAACCATTTTTTATTCTTTCTCTTGGGCACAGACATTTCTTTAAACATG TGCTGACCTTCTGCTTGGAGGTCTCCTTGAGGACATTGTCTCAGAAATCTGTGTTGCAAA ATATTAGAACTGATCACTCATCCCTTTCCACTGTTAAATTTTCTCTACTATCTCACCTTA GGCAATATAAAGTCCTGGTTCACTCTCAGGAACGAGAGCTGACCCAGTTAAGGGAGAAGT TACAGGAAGGGAGAGATGCCTCCCGCTCATTGAATCAGCATCTCCAGGCCCTCCTCACTC CGGATGAGCCGGACAACTCCCAGGGACGGGACCTCCGAGAACAGCTGGCTGAGGGATGTA GGCTGGCACAGCACCTCGTCCAAAAGCTCAGCCCAGGTGAGGTGGCCATAGGCCCTGATG ACCCAAAACCCCAGGCTTATGAGAGACTTCAGACCTCCATACTTTCACAATGACATTTGT ATCGGTGGTGTTTTTTCCCACTAAACGTATGTGGCCGTGACATAAGTGACATAACCAGGA CTTCCTGGGTAAGAACAGAGGTGGGAAACCGATTGGGTTGGAGGTCACAGTATTTCAAAT GTCCCTCCTCCCTTGATGGAAGGTGGTCTTTGGAGCAAGAAGCTGCACGTTTCTAGTTTT AAAGGACAGGAAGGAGGCTGTGACGGGAGGGCGCTTTTTAGAGTGAAAAGAGCTCTGGAC TCAGAAGGCAGGTTCCCAGGCTGTCTCTTTGGCAATGTTCTTAGTAACTGTCGGTGAGTG AGTGATTTATCCTTCCTGAGTTTCTCTGTCTCCATCTGCAAAGGCAGGCAAATTGTCTCT TGCAAGAGTCTGAAGCATCCAAATGTGGGAACACTTAGGACTGCTTTTCAAAATGAGATA AAGCCCCTCGCCATGTGGTGTTAGAGAAGGCACTTGATGTGGGGGCATTTGGTGGTAGGA AGTGCTTGATACTGGAGCACTCTTCATGGAGAGAATGTCCCTGAATAACAGGGCAGAAGC CACATGGAGGGCCTGTGCAGTCTCCTGATGCATAGAGGACTGTAGGGCAAGTTTGTCCTC TCCTAAGAGAAAGAATTAGGTTTGAAATGTGAACTGTGACAGGACACCAAGCCCGTGCCT GGGAATCAGACCTGTAGCCAGATGGGGGAGACAGCTGCCAAAGTTCAGAGAGAGGCTGTA GGAGCCTCCATGATATGGGGAGCAAAAGGTCTTTTCAGTATTTGGCCACATCTTGATGGT GGCCCTCCAGATCAGAAATGCATTGCCTGATGGATCGGGAAACCATGCCAGGGCATTTTG TTAACGATAAAACATGAGAGCTTTCAGCTGAACAGTGACCATGCCTAGATGTTCATGTCT GTGTGCACATTCGGCTGACTGTGCTTGCAGAGTGTGAATTGGGAAATATCTGAATGAACA CTTCTGTATTTACAGAAAATGATGACGATGAGGATGAAGATGTTAAAGTTGAGGAGGCTG AGAAAGTACAGGAATTATATGCCCCCAGGTAACGCTGAATAATCGGGAGCAAGTAATGGG TGGTAACATATGAAAAAGGTCTAGGAGGCACACCCTCTCTGGCATCTATGATGGGCCGAA AGCCTGCATTCCCTTGGCCACAGTATGAGAAACTCAAGCCAGCTTGGACACAGGGTGTGG CAGCTGTTGTGTTTCTCTGTGTGTGGTGGGTGTCATGTCTGTACCGTACAGGGATAGCTG AGTTTTCATCCTCCTCGGCTCCTATCTGTCCAGTGCAATGAACACCAGTTGCTGTCTTCC TCTCTGGCTCCCATGGCTGCCATGCTCTGTTGCAGAGAGAAGAGGATTGCCTGTTCCCTC TTAAAGGGATCCTCCTGTTTGCTTTCTTGGACCACTCTCTTAATGCCTCCTGTCGAAACC AGCTAGCACTCCCTGGTGTCCAATCCCTCTGTGTTTAGTCTTCTGTCATCTCTATCCCAC CTGGCTCATCAGGGAGGTGCAGAAGGCTGAAGAAAAGGAAGTCCCTGAGGACTCACTGGA GGAGTGTGCCATCACTTGTTCAAATAGCCACCACCCTTGTGAGTCCAACCAGCCTTACGG GAACACCAGAATCACATTTGAGGAAGACCAAGTCGACTCAACTCTCATTGACTCATCCTC TCATGATGAATGGTTGGATGCTGTATGCATTATCCCAGGTAGCCTCTATTTTCCTGTGTC TCACACCTTTTCCTATGCTGAGGAATATAAACTCTGAAGACAGGCTCTATACACACAGAT TGGTTTTAATAAAATCTATTATGGTATTCTTAACAGAGATATCAAGGAGGTTTTCTGTCC TTCTCAGCTCATGTCATGCCTTTGTCTCACAGTCCCCAGTGTCAAGTTACTGGACCCCAG ACAAGTGTGACAATCTCATAGTCACCTGAGTGCAGGAGGTACACAGGAAGTATCTGTGAG GCCTCGTACCTTTGATTCAGTATCTCTTGTCACCTGTGATTAAGTCGTCTGTCCCTGAAC AATGTCCATGAAATTTCTCTGCCTTTTTAAGGCGACTGGCAGCCTTGCCTTTGTGTTTGG AAATATTGTTCCCCAGGCTTCACTGCTCTCAGCTTTAATCTTGATCTCCTTTGAGTCTGC TTGGTTAGCTGCACAGTCACCTTGAAATCAGGACAGAAACTTTTCTTTTTTACTTTGCTG ATATAGTTCCATAAAGCAAGGCTGGACCCTGGTTCTCCACCCCATCAATGCAATGGCTGA TGCAATGTTTTGTAGCATCATAGATTCTCTCTCTCTTTTTCTTTTCTTTTCTTTTTCTTT TTCTTTTTTTTTTTGTGATGGAGTCTGGCTCTGTCACCCAGGCTGGAGTGCAATGGCTCC ATTTTGGCTTGCTGCAACTTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCC TGAGTCGCTGGTACCACAGGTGCTCAGCACCACATCTGGCTAATTTTTGTATTTTTATTA GAGACGGGGTTCCCCCATGTTGGCCAGGCTGGTCTTGAACTCATGACCTCAAATGATTCA CCTTCCTTGACCTCCCAAATCACAGATTCTTTTTAATGCAAGAGTTGTTAGAATTTATCT ATCAGTCGAGTTTCATGTGTAGATCCCTCTAAACATTTAATGTCCATGTTACCTGGTGAT ATAAGTCAGTATTGCAACAACACTCCTAGAAAATTGTTTGACCAATTATTGGCGACTTTG GGGGGAAAATTTTGTTTAACTTTGCATAGACTCAGGCAGGGAATATGGCATTATGGTCTA CCCATAGAGGGAAATTTTGGCCTGTGGGTCTGGAAAGCAGGGTCATCTACTTCTCACCAG AGTTAATCTAGGGCACCCTGGAGTGCTCCTGTCAGAATCCATATTCTTGCACTGAGAATA GTTATGTCCTTGTCCTATGACTGGACACTGATTTGGTCATATGTGGAGTGTGAATTGCTT AATGTGACCTGCTTCTCTGAATTTATTTCCAGAAAATGAAAGTGATCATGAGCAAGAGGA AGAAAAAGGGCCAGTGTCTCCCAGGTAATGCCATGGAATTGTGGGCTGTTAATTCAATAG TGGCAGCTGGAGTTTGTAGATTTAGAGAAAATGAGGAAGCAATGAATAGAACTTTTTATT CCATTCACCCAGCTACAAGTTGTCCTTATTAACAATGTTGTACATTATTTGTGGCCCTTG TGTTGGTTTTAATTTCGTAGTCCTCTCAAGATAGGAACTTGCAATCAGATGAGCCAGGTG AACTAGCCAAACAGGGATTTCTTGTTGATCTTTTCAAAAAACCAGCTCCTGGATTCACTG ATTTTTTTGAAGGGTTTTTTGTGTCTCTATCTCCTTCAGTTCTGCTCTGATCTTAGTTAT TTCTTGCCTTCTGCTAGCTTTTGAATTTGTTTGCTCTTGCTTCTCTAGTTCTTTTAATTG TGATGTTAAGGTGTTGATTTTAGATCTTTCCCTTCCTTGTGGGCATTTAGTGCTAGAAAT TTCCCTCTCCACACTGCTTTAAATGTGTCCCAGAGATTCTGGTATGTTGTGTCTTTGTTC TCATTGGTTTCAAAGAACATCTTAATTTCTGCCTTCATTTCGTTATTTACCCAGTAGTCA TTCAGGAGCAGGTTGTTCAGTTTCCATGTAGTTGTGCAGTTTTGAGTGAGTTTCTTAATC CTGAGCTCTAATTTGATAGCACTGTGGTCTGAGAGACAGTTTGTTGTGATTTCTGTTCTT TTACATTTGCTGAGGAGTGCTTGCTGAGGAGTGCTTTACCTCCAACTATGTGGTCAATTT TGGAATAAGTGTGATGTGATGCTGAGAAGAATGAATATTCTGTTGGTTTGGGGTGGAGAG TTCGTAGATGTCTATTAGGTCTGCTTGGTGCAGAGCTGAGTTCAAGTCCTGGATATCCTT GTGAACCTTCTGTCTCATTGATCTGTCAAATATTGACAGTGGGGTGTTAAAGTCCCCCAT GATTATTGTGTGGGAGTCTAAGTCTCTTTTTAGGTCTCTCAGGACTTGCTTTATGAATCT GGGTGCTCCCGTATTGGATATATGTACATTTAGGATAGTTAGCTTTTCATGTTGAATTGA TCCCTTTGCAATTATGTAATGGCCTTCTTTGTCTCTTTTGATCTTTCTTGGTTTAAAGTC TGTTTTATCAAAGACTAGGATTGCAACCCCTGCTTTTTTTTGCTCTCCATTTGCTTGGTA GATCTTCCTCCATCCCTTTATTTTGAGCCTATGTGTGTCTCTGCACGTGAGATGGGTCTC CTGCGTACAGCACACTGATGGGTCTTGACTCCTTATCCAATTTGCCAGTCTGTGTCTTTT AATTGGGGCATTTAGCCTATTTACATTTCAGGTTACTATTGTTATGTGTGAATTTGATCC TGTCATGATGATGTGAGCTGGTTATTTTGCCTGTTAGTTGATGCACTTTCTTCCTAGCAT TGATGGTCTTTACAATTTGGCACGTTTTTGCAGTGGCTGGCTGGTACTGGTTGTTCCTTT CCATGTTTAGTGCTTCCTTCAGGAGCTCTTGCAAGGCAGGCCTGGTGGTGACAAAACCTC TCAGCATTTGCTTGTCTGTAAAGGATTTTATTTCTCCTTCACTTTTGAAGCTTAGTTTCG CTGAGTATGAAATTCTGGGTTGAAAATTCTTTTGTTTATGAATGTCGAATATTGGCCTCC ACTCTCTTCTGGCTTGTAGGGTTTCTGCAGAGAGATCCACTGTTAGTCTGGTGGGCTTCC CTTAGTGGGTAACTCGACCATTCTCTCTGGCTGCCCTTAACATTTTTTCCTTCTTTCAAC CTTGGTGAATCTGACAATTATGTGTCTTGGAGTTGCTCTTCTCGAGGAGTATCTTTGTGG TGTTCTCTGTATTTCCTGAATTTGAATGTTGGCCTGCTTTGCTAGGTTGGGGAAGTTCTC CTGGATAATATCCTGAAGAGTGTTTTCCAACTTGGTTCCATTCTCCCCGTCACTTTCAGG TACACCAATCAAATGTAGATTTGGTCTTTTCACATAGTCCCATATTTATTGGAGGCTTTG TTCATTTCTTTTTACTCTTTTTTCTCTAAACTGCTCTTCTCACTTCATTTCATTAATTTG ATCTTCAATCACTAATACCCTTTCTTCCACTTGATCGAATCGGCTACTGAAGCTTGTGCA TGTGTCACGTAGTTCTCGTGCCATGGTTTTCAGCTCCATCAGGTCATTTCAGGTCTCCTC TACATTGTTTATTCTAGTTAGCCATTCGTCCAATCTTTGTTCAAGGTTTTTAGCTTCCTT GTGATGGGTTTGCACATCCTCCTTTAGCTCGGAAAAGTTTATTACCGACTTCTGAAGCCT ACTTCTGTCAGCTCATCAAAGTTATTCTCCGTCCTGCTTTGTTCCATTGCTGGTGAGGAG CTCTGATCCTTTGGAGGAGAAGGGGCGCTCTGGTTTTTAGAATTTTCAGCTTTTCTGCTC CAGTTTGTCCACATCTTCGTGGTTTTATCTACCTTTGGTCTTTGATGCTGGTGACCTACA GATGGGGTTTTGGTGTGGATGTCCTTTTGTTGACGTTGATTCCTTTCTGTTTGTTAGTTT TCCTTTTAACAGTGAGGTCCCTCAGCAGCAGGTCTGGTGGAGTTTGCTGGAGGTCCACTC CAGACCTTCAAACAGGGATTTCTTGGTGTCACCTGTTCTCTCCCATGTGTTTAAATCCAG GGAGAGAATGTATAAATGCTTTCTGCTTATTTTTTATTAGTGTGTTTGCTAGTATTTGTG TAAGCAAAGAAATTGAAAAAATAAACATATTATATCAAAATATTGTAAAAAGGGGACCCT TAATACACAAGATCTGTGTCTGCACTGCCTCAAGAGCTCTGTTCACTTGAATGCTGCATG TAAAATTCATCCCAATTTAGACGAAGTAGTTGAAGCCCTGTGTTAGTTCTCTGTGCTGCA AGTCATGATGGTAGTTTACAGAGAGAGTCTGGGTGCCCTGCATTGGCTGATCTGTGGCAA ATGTACTGAGCACGTGCTGCCCATTTTTGTTCGGTCCTCAGAGCAGTCACCCTCCAGCCT GCATTTAGAAGGATAGTTTTATTTCTCTTGAAGGAAAAATGCCTTTGGTTTCTGTGAGCA CTCCATTCTGTCTCCCATCAGATCATCTGGAAGGTTTTGTTGTCTAATCTCTGTTGGTTA TATCTTCTGTCATCCCTGTCCTGCCTGGCTCATCAGGAATCTGCAGGAGTCTGAAGAGGA GGAAGCCCCCCAGGAGTCCTGGGATGAAGGTGATTGGACTCTCTCAATTCCTCCTGACAT GTCTGCCTCATACCAGTCTGACAGGAGCACCTTTCACTCAGTAGAGGAACAGCAAGTCGG CTTGGCTCTTGACATAGGCAGTGAGTACTCCATTTTGAAGGTGATAAAGCTCCAGTTCAT GTCCCAGGTAGACCCCATAATCTTTGGGCCTTGTGACCCTGGTTGGGCTGAGAGTTGCCA TCACTGTGGGTGGAACCTATATATCAATGTAGATTTCAATCACTCTGGAATCGAGTCTGA AGCACAGGCGTGGGGTGGGTCAGTGAGCTTTGCTCTCTTCCTAGTCTCAGGCCATGCCTG TGCCACCCTGGACTGACTGTCAGGACACTGAACACAAGACGGGCGTGGCAAACTCACACC AAGCTGTGCAGCATATGTCCAGGAGTTGTCTGTCAGATCAGCTCACCTGAGTTAAACGTC TCTTGCCAGCTACAAAGTTCTTTATGAGTTTTGTTCCCAAAGCATGTCTGTGCAGTGCTT TACCTGCCCAAGGCCAGTGTCACCCTTGTCTACCTCTCCGTGGAAGATGTGACCCAGGTT TCACTGAATTTTTCCCCCTTTTCTGTGTCTTCTAAGTTGGCTTGTCATAGCTCATCTGTC CATCATCTTGCTGGTATGTTTTCTAGATAAATGGCTGACTTTTCACCCACAAAAGCCATG ATAGCTGATGCTTCTGTGTAGAACCAAGTGTCACTTTGACTCAAGAGCTGGTACATTGCA CCCCTCCATCAAATCTCAGTGTCCACAATCTCATAAACTATCAAATCTGGGTATTTGAAG AGAGAAGCCTGAATATTGCAGTATCTCTCCTATGAGGCATTAGAATGATTTGCCTCAAAT CTATTGGGAAAAACATTGCTCATTTGTGTACACAAACCTAGGACAGAGCACACTGGGAAG ATCACATTCCAAAACAGGGGCATTTTGCCCAAGGCTCATGAAAGGAACCAAGTCAGTTCT CTCAAGACTTGCCCTCAGGCCTCCTGGTATATTTCTCTCAAAGTCTCCTATTCTCACACT GAGAAGACTGATGTCCCTGTGTTAGGATTGGACAGAGGAATGTTTCCGTGTGCAAGGAAG AACTGCTTCATGTAAGAGGCCCTGTCTGAATTTATTTGCAGGACATTGGTGTGATCAAGT GAAAAAGGAGGACCAAGAGGCCACAAGTCCCAGGTGAGTCTGAGAAATTATGGACAGTTA ATTTGATGTTGACACCTGGAGATGCCAAGTCCGGGGAAAGCAGTACATGCTGAAAATGAT GATTTCATCTTGTCAGACAAGTCTGAATTATGTCTACTAACATTGCTTTTGGTTCTCATT ACAGTAAATGTTTAGGTTTCCATTTCTTCCTATCCTTCTCATTTACTAACCTAGTGAAGG TTGACCATACTTCAAAAGCTGTATTCTCATGGTGACTGCAGGGAAGCTTGAGCACATTTT ATGCAAAATTGTTGAGCCCACTCTTTTCATGATCACTGTTCATTGTGTGTCCTGAAGGCA CAAATATAGAGTGTTCTTTGACTCTCTCATCAGTGTGTCACCTGGCCAATTCACTGAGCT CACTATCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTATGTGTATGTCTTTCTCTTTCATCCTTTTCTACCTGGCCCTGGTCTGTCCCAAC ATGAAGGCAATAATTTGTTACCTCATTAATAGATCTGTCCTTTTTCTTTTCAAACAGTTC CTTATGTTACCCATGAAATCTAGCTGGGGCTGTGTGGTTTCTGATTCCCCCTGGCTTATT CTTTACTTTTCCTACTTTTCCAGGCTCAGCAGGGAGCTGCTGGATGAGAAAGAGCCTGAA GTCTTGCAGGACTCACTGGATAGATTTTATTCAACTCCTTTTGAGTACCTGGAACTGCCT GACTTATGCCAGCCCTACAGAAGTGACTTTTACTCATTGCAGGAACAACACCTTGGCTTG GCTCTTGACTTGGACAGTGAGTACCTTACTATGAAGGTGATAAGACTCCACCTGGTCCTC CAGATATGGGTGATATTCCTGTTCCAAGTGGCCCTTATTGACCCGAGAGATGTCATTGCC ACAGGCAGGACCCGTGGGCGCATAGAGGTTGTAATGAAATTGTAGTTTCAGTTGGAAGCC CAGACATGAAATGGGTCAGTGAGCATGGCTCTATTCCTAGTCTCCAGCCATGCCTGTGGC AACCTGAGCCCACTCTCAGCACATTGGACCCAGGCAGGTGTAAAAAATTCACAGAACCAT GATTTGGACTCAAGGGTTTGTAGATTTCCTCCTTCATTCAAATTTCAGTGTCTTGCAACC ACGAATGAGCTGGGCATTTGATGAGACAGGGCTGAATACTGCAGTTTTCCTCCTAGAAAT CATCTGGGGCATTTTCTTTGAATTGATGGGAGCAATAAGGCATAACTGTTTGCACAAACT TGGGATAAATGATTTTGGGATAACTGTCTACCAGAATAGGGACATTTCACCCTTGGTTCT GAGATGCAAACCAAAGAATCTCTATCATGACCAGCTTTGAGGCCTCCTGAAGTATATCTC TCACATTGTCCTGTTCTCATGCTGAGGAGCCTGAGGTCCCTGTGTGGGGATTAGACAGTG GACTGTTAATGGGTGTAGGTGAATTGGCTTATCTTGTCTGTCCCTGTCTGAATTTATTGC AGGAATGAAAAAGGACCAAGAAGAGGAAGAAGACCAAGGCCCACCATGCCCCAGGTAAGT TTGAGCAATTGTCAACAGCTAATTCTGTGTTGACACCTGGAGACTCCTGGTTCAGGGAAA GCAGAGCAGGCCGACATTATCGATTACATGTTTTCAACCAAGCCTGAATTATTCCTACTC ACATTGCTATTGGTTTTCATTGCAGTAGATATTTAGGTTTCCGTTTCTTCCTCCCCTTAT CACTTACTAACCTACTGTAGGTCGACCATACTTCAAAAGCTGTATCCTCATGGTGACTGC ATGGAAACTTGAGCACATTTTATGGAAAATTATTGAGCACAGTCTTTTCATGATCACTGT ATGCTGTGTGCCCTGAGGGCACTAACTCAGAGTGTCCTGTACTCCCTCCTCAGTGTGTCA CCTGGACAATTCAGTGAGCGCTCACTCTCTCTCTCTCTGCCTCTGTCTCTCTGTCTCTCT GTCTTTCTCTTTCATTCTTTTCTGTTTGGCCCTGTGCCATCCCAACTGAGGGCAATAATT TGTTACCTCATTAATGGATGTATCCTTTTTCTTTTTTAACCACTTCCTAATGCTACCCAT GAAATCTAGTTGGGGCTCTGTGGTGTCTGATTTCCCCTGGCTTATTCTTTACTTTTTCTA CTTTTCCAGGCTCAGCAGAGAGCTGCCGGAGGTAGTAGAGCCTGAGGACTTGCAGGACTC ACTGGATAGATGGTATTCGACTCCTTTCAGTTATCCAGAACTGCCTGATTCATGCCAGCC CTACGGAAGTTGCTTTTACTCATTGGAGGAAGAACACGTTGGCTTTTCTCTTGACGTGGA TGGTGAGTACCTTTCTATGAGGGTGATAAGGATCCACTGAGTTTTCCGTATAGAGATCCT ATTCCTGCTCTAAGAGGCCGTTACTGAGCTGAGAGATGTCATTGCTGCACTGAGGACCTA TAGGCACATATAGGTTGAACGAAACTCTAGTTCTACCTGGAAGCCCAAACATGGGATGGG TCAGTGAGCGTGGCTCTCTTCCTAGTCTCAGGCCATGCCTGTGGCACTCTGATTCTACTC TCAAGGCATTGGACCTGGGCAGATGGGACAAATTCAGAGAACTATGATTTTGACTCAAGG GTTTGTAGATTTCCTTTCTCACTCTAATTTCAGTGTCTAAAATCCTCACAACTATGAACA ATCTGAGTATTTGATGAGACAGGGCTGAATATTGCAGTTTTTCTCCTAGAAATCGTTTGA GGGCATTTGCTTTAAATTGATTGGAAAGATATGGCATAACCGTTTGCACAAACTTGGGAC AAATGATATTGGGATAATGATCTACCAGAATAGGGACATTTTACCCTTAGTTTCTGGGAC AAAAACCAAGGAATCTCTATCATGACCATCCTTCAGGCCTCCTGAAATATATCTCTCACA GTGTCCTATTCTTATGCTGAGGAGCCTGAGGTCCCTGTGTGAGGATTAGACAGTGGAATG TTATGTGTGTAGGGGAATCAGCTTAATGTGTCTGTCCATGTCTGAATTTATTGCAGAAAT TGAAAAGTACCAAGAAGGGGAAGAAGATCAAAAGCCACCATGCCCCAGGTAACTTTCAGC AATTGTGGTCGCTTAATTCTGTGTTAACACCTGGAGACAACAGATCCAGGGAAAACAGTG TGTTTGATTTCATGTTTTCAATGAAGGCTGAATTACTCCTGCTGACATTGCTATTGGTTT TCATTGCAGTAGACGTTTAGGTTTTCATTTCTTCCTCCCCTTATCATTTACTAATGTACC ATAGGTTGACCATACCTCAGAAGTTGTACCCTTATGGCGACTGCATGGAATTTTAAGCAC ACTTGATGGAAAACTATTGAGCTCACTCTTCTCATGATCACTGTTTGCTGTGTGTCCTGA GGGCACTAACTCACAGTGTCCTTTTACTCCCTCATCAATGTGTCACCTGGCCAATTCACT GAGCTCACTTTCTCTCTCTCTCTGTCTCTCTCTCTCACTCTCTGTCTTTCTCTTTCATTG TTTTCTACTTGGCCCTGTTCTATCCCAACATAAAGGCAATAATTTTTTTACCTCATTAAT GGAACTATCCTTTTCCTTTTTTGACCACTTCCTTATGTTACCCCTGAAATCTAGTTGGGG CTCTGTGGTGTCTGATTTTCCCTGGCTGCTTCTTTAGTTTTGTCTCCTTTTCCAGGCTCA ACGAGGTGCTGATGGAAGCAGAAGAGCCTGAAGTCTTGCAGGACTCACTGGATAGATGTT ATTCGACTACTTCAACTTACTTTCAACTACATGCCTCATTCCAGCAGTATAGAAGTGCCT TTTACTCATTTGAGGAACAGGACGTCAGCTTGGCCCTTGACGTGGACAATAGGTTTTTTA CTTTGACAGTGATAAGGCACCACCTGGCCTTCCAGATGGGAGTCATATTCCCACACTAAG CAGCCCTTACTAAGCTGAGAGATGTCATTGCTGCAGGCAGGACGTATAGGCACATGTAGG TTTGAATGAAACTGTAGTTCCCTTTGGAAGCCCAGTCATAGGATGGGAAAGTGGGCATGG CTCTATTCCTATTCTCAGACCATGCCAGTGGCCACCTGTGCTCAGTCTGAAGACGTTGGA CCCAAGTTAGGTGTGACACGTTCACACGACTATGTAGCACATGCCGGGAGTGATCTGCCA GACATTCTAATTTGAACCAGATATCTCTGGGTAGCTACAAAGTTCCTCAGGGGTTTCATT TTGCAGGCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTTTGTGTTTAG CTCATCCAAAGGTGTTACCCTGGTTTCATTGAACCTAACCCCATTCTTTGTATCTTCAGT GTTGGTTTGTTTTAGCTGATCCATCTGTAACACAGGAGGGATCCTTGGCTGAGGATTGTA TTTCAGAACCACTGACTGCTCTTGACAGTTGTTAACCCACTAGGCTCCTTTGAGTAGAGA AGCCATAGTCCTTCAGCCTCCAATTGATATCAATACTTAGGAAGACCACAGCTAGACGGA CAAACAGCATTGGGAGGCCTTAGTCCTGCTCCTTTCAATTCCATCCTGTAAAGAACAGGA GTCAGGAGCCGCTGGCAAGAGACAGCATGTCACCTGGGACTCTGCCAGTGCAGAATATGA ACAATGCCATGTTCTTGCAGAAAATGCTTAGCCTGAGTTTCATAGGAGGTAATCACCAGA CAACTGCAGAATGTAGAACACTGAGCAGGACAACTGACCTGTCTCCTTCACACAGTCCAC GTCACCACGAATCACACAACAAAAAGGAGGAGAGATATTTTGGGTTCAGAAGAAGTAAAT GATAATGTAGCTACATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGT TGTTGTCATTGATTTTGGTGACATGGACTTGTTTGTAGAGGACAGGTCAGCTGTCTGGCT CAATGGTCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTCAGCCTAAACG TTTCATCAAGAACACTACAGAGTCGATACTGTGAGTTTCCAACCTCAGCCCATCTGTGGG CAGAGAAGGTCTAGTTTGTCCATCAGCATTATCATGATATCAGGACTGGTTACTTGGTTA AGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATGATGAAGTATTTGG GAGAGTGGTTTTTCAAAGTAGAAATGTCCTGTATTCCAGTGATCATCCTCTAAACGTTTT ATCATTTATTAATCATCCCTGCCTGTGTCTATTATTATATTCATATCTCTACGCTGGAAA TTTGCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGTTGAAAAAAAA ACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAA CTTTTGCCTATCACTCTGGACTGTTGGATTGTTTTTTACATTCAGCGTTATAATCTTTTG TTATGCTGATTGGTTTTGGTGGGTACTGATGCGAATTAATAAAAACATTTTCATTTCC bcftools-1.21/test/csq/ENST00000318249/ENST00000318249.fa.fai000066400000000000000000000000211467060157400215360ustar00rootroot000000000000001 44878 23 60 61 bcftools-1.21/test/csq/ENST00000318249/ENST00000318249.gff000066400000000000000000000116151467060157400211670ustar00rootroot000000000000001 ensembl_havana gene 1 44878 . + . ID=gene:ENSG00000142794;Name=NBPF3;biotype=protein_coding;description=neuroblastoma breakpoint family%2C member 3 [Source:HGNC Symbol%3BAcc:25076];gene_id=ENSG00000142794;logic_name=ensembl_havana_gene;version=14 1 ensembl_havana transcript 11 44772 . + . ID=transcript:ENST00000318249;Parent=gene:ENSG00000142794;Name=NBPF3-201;biotype=protein_coding;ccdsid=CCDS216.1;tag=basic;transcript_id=ENST00000318249;version=5 1 ensembl exon 11 221 . + . Parent=transcript:ENST00000318249;Name=ENSE00001542593;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001542593;rank=1;version=1 1 ensembl five_prime_UTR 11 221 . + . Parent=transcript:ENST00000318249 1 ensembl five_prime_UTR 4821 4959 . + . Parent=transcript:ENST00000318249 1 ensembl exon 4821 5092 . + . Parent=transcript:ENST00000318249;Name=ENSE00003631247;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003631247;rank=2;version=1 1 ensembl CDS 4960 5092 . + 0 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 28561 28770 . + . Parent=transcript:ENST00000318249;Name=ENSE00003487448;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003487448;rank=3;version=1 1 ensembl CDS 28561 28770 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 30505 30607 . + . Parent=transcript:ENST00000318249;Name=ENSE00001724864;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001724864;rank=4;version=1 1 ensembl CDS 30505 30607 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 31442 31656 . + . Parent=transcript:ENST00000318249;Name=ENSE00001617203;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001617203;rank=5;version=1 1 ensembl CDS 31442 31656 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 32716 32788 . + . Parent=transcript:ENST00000318249;Name=ENSE00001618625;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001618625;rank=6;version=1 1 ensembl CDS 32716 32788 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 33253 33458 . + . Parent=transcript:ENST00000318249;Name=ENSE00001316812;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001316812;rank=7;version=2 1 ensembl CDS 33253 33458 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 34773 34824 . + . Parent=transcript:ENST00000318249;Name=ENSE00003569827;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003569827;rank=8;version=1 1 ensembl CDS 34773 34824 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 38017 38180 . + . Parent=transcript:ENST00000318249;Name=ENSE00001619353;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001619353;rank=9;version=1 1 ensembl CDS 38017 38180 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 39222 39273 . + . Parent=transcript:ENST00000318249;Name=ENSE00003497364;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003497364;rank=10;version=1 1 ensembl CDS 39222 39273 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 39924 40096 . + . Parent=transcript:ENST00000318249;Name=ENSE00003594154;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003594154;rank=11;version=1 1 ensembl CDS 39924 40096 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 40803 40854 . + . Parent=transcript:ENST00000318249;Name=ENSE00003524606;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003524606;rank=12;version=1 1 ensembl CDS 40803 40854 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 41470 41642 . + . Parent=transcript:ENST00000318249;Name=ENSE00003655848;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003655848;rank=13;version=1 1 ensembl CDS 41470 41642 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 42357 42408 . + . Parent=transcript:ENST00000318249;Name=ENSE00003531648;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003531648;rank=14;version=1 1 ensembl CDS 42357 42408 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl CDS 43016 43259 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 1 ensembl exon 43016 44772 . + . Parent=transcript:ENST00000318249;Name=ENSE00001277853;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001277853;rank=15;version=3 1 ensembl three_prime_UTR 43260 44772 . + . Parent=transcript:ENST00000318249 bcftools-1.21/test/csq/ENST00000318249/ascii-art.txt000066400000000000000000000001321467060157400212640ustar00rootroot00000000000000 4959 GA G 4960 xxxxxxxxx CACACTGGGGATGCCACTGAC G- bcftools-1.21/test/csq/ENST00000318249/start-lost.txt000066400000000000000000000001711467060157400215270ustar00rootroot000000000000004959 GA G start_lost|NBPF3|ENST00000318249|protein_coding|+ 4959 GA G start_lost|NBPF3|ENST00000318249|protein_coding|+ bcftools-1.21/test/csq/ENST00000318249/start-lost.txt-l000066400000000000000000000001711467060157400217600ustar00rootroot000000000000004959 GA G start_lost|NBPF3|ENST00000318249|protein_coding|+ 4959 GA G start_lost|NBPF3|ENST00000318249|protein_coding|+ bcftools-1.21/test/csq/ENST00000318249/start-lost.vcf000066400000000000000000000005051467060157400214670ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 4959 . GA G . . EXP=start_lost|NBPF3|ENST00000318249|protein_coding|+;type=ENST00000318249:21771579-GA-G bcftools-1.21/test/csq/ENST00000318249/start-lost.vcf.ori000066400000000000000000000003121467060157400222530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO=1 1:16330731-16335302 ACATCCTGGAAGAGTGGCCTAGGACAGCTCCTCTCCTGCCAGAGCTAGGCAGGCGCCGAA GTAGCCGCATGGCCCCGTCAGAAGACCCCAGGGACTGGAGAGCCAACCTCAAAGGCACCA TCCGTGAGACAGGCCTGGAGACCAGCTCCGGTAAGAGGCGGCAAAGGGACCCCAGCCCCA CAGAAACACCAGCTGGGGGCCAGGTGCGGTGCCTCATGCCTGTAATCCCAGCACTTTGGG AGGCCGAAGCGGGCAGATCATGAGGTCAGGAGTTCGAGACCAGCTTGGCCAACATAGTGA AACCCCATATCTGCTAAAAATACAAAAAATTAGCTGGGTGTGGTGGCGGGTGCCTATAAT CCCAGCTACTCAGGAGGTTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCA GTGAGCTGAGATCGCACCACTGCACTCCAGCCTGAGCAACAGTGTGAGACTCCATCTCAA AAAAAAAAAAAAAAAAAAAAAAGCAAGACCAGCTGGGGGTGGGTGGGGGTCTGATGGCAA ACATGCTACCTCCCTTGGGTTGCTGGGATTCTCCAGCCAAGGGCGGGCTCGTTTTATTTC CTGTGCTAGCCAACCTACTAGAACATAAGCTTCCTTCTGAGCCCACGTCGTGTTTCACAG CACGTAGCTAAGAGAATGGATGTGTATGTTATTTGGGTAACTCAAAAAGTTACCTTTTTA AGAGCACAGGCTTTGGATTCAGATACAATTGCTCAGACACCTGCTTCATTGATAAGTCTA TTGGCTGGTTTGTCCATCCCTCTACCCTGTGCTGGGCTCTGAGCGGGGGGATTGCCAGGG CAAATGCCACCAGGTACTGATGGGATTCTCTGAGGCTGTGGACAAGATTATCTGGGGAGG GGGAGAGTAGCAAGATGCTCCCTGAGACCCACCAACACTTGTGCAGGCTGAGCCTCAGTT TCCTCACCTGGAAAGATGGCCAGGGCTTTCCTCTCTGGGGTTGAGGACTGTGCTTTTCAT AATATGGTCCATGGACCAGCAGAATTGGCATCCCCTGGGGACTTGTTAGAAACGCGAGTC TCAGGCCCCACCCCAGCCCCACTGCACCAGACTCTGCATTTTAACAAGCTCCCCAGGCAG CTCATGGGAACAGCAAAGTTGGGAGGCACTGACATGTTGGACTCTGTGTTCCTGGAAGGC AGATGGATGGATGGTAAGTGGAGACTTGAACTCAGGTCTCTCTGATGCTGAAGTCCATAC ACTTAAACCCTGACTGTCCTCCTCTGTTGGTGTATCAACCAATCCAGTTGAACCCTATCG AATGAATAAACAAATGAATTCAGGAAACCATGTCCCAGTCGGGTGCAGTGGCTCACGCCT GCAATTCCAGTACTGATTGGGCTGAGGCAGAAGGATTTCTTGAGTCCAGGAGTTTGAGAC CAGCCTGGGCAACATAGGGAAACCTCATCTCTACAAAAAATTTTAAAATTCACCAGGCAT GGTGGCATGAGCCTGTAGTCCCAGCTACTTAGGGGGCTGAGATGGGAGGATTGGTTGAGC CCCCTGAGGCTGAGGCTGCAGTGAGCCATGACCTCCAGCCTGGGCGACAGAGTGAGACCC TGTCTCAGGGGAAAAGAAAAGTCCCCTGCTTGTGCTAACTTTTGGTCTTTTCCTCTCTTC TAGGTGGGAAGCTGGCTGGCCATCAGAAGACCGTCCCCACGGCTCACCTGACTTTTGTTA TTGACTGCACCCACGGGAAGCAGCTCTCCCTGGCAGCAACCGCATCACCACCCCAAGCCC CCAGTCCCAATCGAGGGCTTGTCACCCCACCAATGAAGACCTACATCGTGTTCTGTGGGG AAAACTGGCCCCATCTGACTCGGGTGACCCCCATGGGTGGGGGATGCCTTGCCCAGGCCA GGGCCACCCTGCCGCTCTGCAGAGGGTCTGTGGCCTCAGCTTCCTTCCCAGTCAGCCCGC TCTGCCCCCAGGAGGTTCCCGAGGCTAAGGGGAAACCCGTGAAGGCTGCGCCTGTGAGGT CTTCAACTTGGGGAACAGTCAAGGACTCACTGAAAGCCCTCTCCTCTTGTGTCTGTGGGC AGGCCGATTAGCTGGAAGGGCCGGGCTCTGATGCCCAGAGGCTGCAATTCCCAGGGCCTG GCCCTGCTTCCCCAGCTAAGCAGGAGTCTTTTGTGCTTGAGCCAAGGAAACATCATTAGA TCCGCTAAGGGGCATCTGAAACATCCGTCGAGTGGCAGAGGCAGGATAAGTCACCTGCAC ATGAAGAGACTCATTCATTCATACAGCAAATATTACTGGTACATCTTCCACATGCCAGGC CCTGCAAAGTGCTGGGGAGATACCATGGTTTTCCTGGAGCTGGTATTTTTGGGGTGGAGG GAACCCACCCTGAATAAATAAAGTAACCCAATAAATAAAGAAGATGATTTTGAACAGCGA TGAATGCTCTGCAGGAACTGAAACAGGATGCTAGAGGGAGAGTGATTGGGGTGAAGACCT TTCCTGATGCAGTGCTTGGTAAGGGCCTCTCTGCGCAGGCAACAAAGTGTGATCTAAAAG ATGAGAAGGGGCCAGCCCTGAGAAAATCCACCCTCCCCAGGGCCACCTGCTGTCATCTTA CCCCAGGGCAGGCCAGAGCAGTGGTCAGAATGCCCCAGCATGACGGGGAGGGGCAACGGG TTTCTTGCTGCCATCTTGGCTCAGAGGCGAGTGTGTAGGTCACTGCAAAGGCAGGGGATA CCACGTGGGGAGACTCGAGGGCCATGCCAGTTGGGGCTGGGAGGCTCAGGGAAGTTGGCT CCAGGAGACTCCATCCCATAAGGCAGCCCAGGTGGGACCTGGGGATCTGAGATGGGAAAT AAGGGGATCTGGCTTCTCAAAAGGGAGGGAGGTACTCAAAAATAGAGTATCATGTTTGAA CGAATGAAAACAAGACATGTTATTTATTGAGCATCTACTGCATACCAGGCTCATGCTGCC CTCTAGGGATAGCAAAAAAAAAAAAAAAAGGTGGGGGGAGGAGGTTCACCCCTCAGGGCA ATCGTGTTCCCTGAGCAGGAGGTGGAGTTACTGGTGTGGGTGTGAAGGTGTCTGTGAGTC TAAGGCATGCACAGCACTGTGAGAAACCCTAAAGCAACCTATTTAAGGAAGTCAGTCTCA AAGCTCCCAGATAAAAATCACTGGGTTTTTCTGTATTTATTTTAGAGACAGAGTCTCACT CTATCACCCAGGCTGGAGTGCAGTGGAACAATCACAGCTCACTGCAGCCTCAAACTCCTG GGCTCAAGTGATCCTCCTGCCTCAGCCTCCCGAGTAGCTGAGACTATAGGTGCACCACTA CGCCCAGCTTGACTTCTTTTAGTAGAGAAGAGGTCTCACTGTGCTGCCCAGGCTGGTCTT GAACTCCTGGCCTCAAGCTATCCTCCCGCTTCAGCTTCCCTAAGTGCTTGGATTATAGGT GTGAGCCACCGTATCTGGTCATTAATTTATTCAATGACTATTTTACTAGGTTCCTACAAA TACTAGCTGCTAACATTTAACATGTAATTGACCATTTACTCTGTGTCAGAGAAACAACAT GGGCACTGTATTTGTGACCATTTTATAGATTAGAGAGCTGAGGCACAGAGAGGTTGAAGA ATGGACTCAAAGTTCCATAGACTGGTACCATTGAGATTAGAACTCAGGCAAGTCTGGTGC CCATATTCTTGCTTGTAACTGTAAGGTATATACCCTCTCATCCTGGTAGCGTCTCTTCTA GGCAGAGGGGACACACAGAGGATAAATGTAACCCTGTCCTCAAGGAGCTCACAGCCAGGT GGGGGAGGCCAGAAAGAAAGCACACAATTGCCATAGCTTCTGAGAAGTGCAACAGTAAGG GCAACACAGAATGATGCTGGAGGACAACCAGCCCACTCTAGAGAGAGGAGATCAGGGAGG ACTTCCTGCAGGAAGTGATGCCGAAAATGAGATCTGACCGGTGACTAAGCTATACAAAAG GGTGGGGTGGGGGAGCAAGTGGGGAGTGCTCTGGGCAGAAGGACCAGTCGTTCAGTCTGG CTAGGGTAATTGTCATTCATTCATTTATTCACCAAGTATTTATTGGGCATCCACTGAATG CCAGGCTTTGGGCTAAACCATGAGATGGAGCAATGAATAAGACAATGAGGCCCAGCCACA AAATAGTTTATCCTCTAGTTGGGGGAGACAGGCAATGCACACACACAAAACAAACAGATC AGAAAGGTGGCAGGAGGCCAGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAG GCCAAGGAGGGGGAGGCGGGGGGAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGC CAACTTGGCGAAAACCCGTCTCTACTAAAAATATAAAAATTAGCTGGGCGTGGTGGTGGG CACCTATAATCCCAGCTACTTGGGAAGCTGAGGTGAGAGAATTGCTTGAACCTAGAAGGC AGAGGTTGCAGTGAGCCGAGATCTCGCCACTGCACTCCGGCCTGGGTGACAGAGCAAGAG CAAGACTGTCTC bcftools-1.21/test/csq/ENST00000329454/ENST00000329454.fa.fai000066400000000000000000000000201467060157400215350ustar00rootroot000000000000001 4572 23 60 61 bcftools-1.21/test/csq/ENST00000329454/ENST00000329454.gff000066400000000000000000000023631467060157400211670ustar00rootroot000000000000001 ensembl_havana gene 1 4572 . + . ID=gene:ENSG00000183888;Name=C1orf64;biotype=protein_coding;description=chromosome 1 open reading frame 64 [Source:HGNC Symbol%3BAcc:28339];gene_id=ENSG00000183888;logic_name=ensembl_havana_gene;version=4 1 ensembl_havana transcript 1 4572 . + . ID=transcript:ENST00000329454;Parent=gene:ENSG00000183888;Name=C1orf64-001;biotype=protein_coding;ccdsid=CCDS166.1;havana_transcript=OTTHUMT00000026317;havana_version=1;tag=basic;transcript_id=ENST00000329454;version=2 1 ensembl_havana five_prime_UTR 1 68 . + . Parent=transcript:ENST00000329454 1 ensembl_havana exon 1 150 . + . Parent=transcript:ENST00000329454;Name=ENSE00001310857;constitutive=1;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001310857;rank=1;version=2 1 ensembl_havana CDS 69 150 . + 0 ID=CDS:ENSP00000332162;Parent=transcript:ENST00000329454;protein_id=ENSP00000332162 1 ensembl_havana CDS 1684 2111 . + 2 ID=CDS:ENSP00000332162;Parent=transcript:ENST00000329454;protein_id=ENSP00000332162 1 ensembl_havana exon 1684 4572 . + . Parent=transcript:ENST00000329454;Name=ENSE00001294049;constitutive=1;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001294049;rank=2;version=3 1 ensembl_havana three_prime_UTR 2112 4572 . + . Parent=transcript:ENST00000329454 bcftools-1.21/test/csq/ENST00000329454/boundary-deletion.txt000066400000000000000000000000311467060157400230320ustar00rootroot000000000000004572 CA C . 4572 CA C . bcftools-1.21/test/csq/ENST00000329454/boundary-deletion.txt-l000066400000000000000000000000311467060157400232630ustar00rootroot000000000000004572 CA C . 4572 CA C . bcftools-1.21/test/csq/ENST00000329454/boundary-deletion.vcf000066400000000000000000000004401467060157400227750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 4572 . CA C . . EXP=.;type=ENST00000329454:16335302-CA-C just after bcftools-1.21/test/csq/ENST00000341065/000077500000000000000000000000001467060157400166435ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000341065/ENST00000341065.fa000066400000000000000000000471141467060157400207760ustar00rootroot00000000000000>1 1:860260-879955 CCAACGAGTTCCAGTTCGTCAGCGGCCGCGAGACGGCCAAGGACTGGAAGCGCAGCATCC GCCACAAAGGTGCCGCCGCCCCTCCCTTCGCTGCCGGGACCCGCGGGCCCCGACCCCACC CCCTACCCGACTCGGACACCCGGGAGCCTCCGGCTCGGCCGAGGGGGCGCTGCAGCTCCA GGGCTGCGCGGGGACACCCCCGCCGCGCGCGGAGGCCTCGGTGAACACGGACAGATCGCC CCCCGCTGCACCTCCCCCCAGCTTGGGCCACAGCGCTTGGGGCTCGCGGGCCGCTCCCTC CGCTCGGAAGGTCTCTGCGAGGCTCCTGGGCCTTAAGGCCCGAAGGAAGTTTACGGGGAC TCGAGAGAGCGGGCAGGAGGCGGGTTGGGAGGGCGCGGAGCCCCGGGTTCGGGGGAGACT GGAGGGGCGCACGTGCGGCCGGGTGCGAGCGCGCGGCGGGGGAGGCTGCGGGGCGGCGCG GGGGCGCGCGCGGAGCCCGAGCGGCGGCGCCAGGTCACACAACCTGTTTTGGCGCCTGCG GGCGCCTGGGCCCAAGGGTGCGACGCGGGGGCGCCTGAGCCGGGACACAGGGGGTGCGGT GAGCGCCAGGCGCCGCGGGGAGTTAAAAAGTTCGGGACCTGAGCGGTGCGTGGTTCCGCG GTGGCCGCCTCTTCCTGCCGCGCAGGCCGAGGGTCCCGACGGCGCCGCTCACCGCTCCGG GACTCAGCCTTTCTGGGCCCGGCCTGCGGTTCCCTCGGGGCCGGGGAGAGGGTGGAGCGC GGGAGGAGGGGCGCCGGGTGGGGACGCCCAGGCCCTTCGTCGGGGGAGGGCGCTCCACCC GGGCTGGAGTTGCAGAGCCCAGCAGATCCCTGCGGCGTTCGCGAGGGTGGGACGGGAAGC GGGCTGGGAAGTCGGGCCGAGGTGGGTGTGGGGTTCGGGGTGTATTTCGTCCACGAGCCG GGGAGGGGGTACTGGCCCTGCCGCTGACTGCGCGCAGAAGCGTGCCGCTCCCTCACAGGG TCTGCCTCGGCTCTGCTCGCAGGGAAAAGTCTGAAGACGCTTATGTCCAAGGGGATCCTG CAGGTGCATCCTCCGATCTGCGACTGCCCGGGCTGCCGAATATCCTCCCCGGTGGTGAGA TGCGGGGCTCGGTTGGGGCTGGGAGTTACTCTCCCCTGCGGAGCTTGTCCCTGCGGTTTT CAGGGTTTTCAGGATCGAGAGTCCTAACCTCACCCCTGCGGGTGTGCTGGAGGGAGCCTC CGAAGGGCAGGGGGAAGCGGCTTTACCTCGTGCTCTCCCAGCCCTTCTACCTGGACGGGG GAGGAGTCCTCGGGCACCCGAGCGCCCTCCCCGGTGGAGACAGGGGGGCCGCGCTTGTCT TAGAGCCTCCCCTTGGGTGCCTTTTAGCTGCTTATCCTCGAGTCCTGGGTCAGGGTCTTC TCCCTGGGAGGAGTAATTCAACGTGGGCCTGGCACTGTGCCCTGTCACCGCTTGGGGGTC ACCGTGTTCTCTGGCCCAGCTGGTGAGGTGTGATTCTGGGACGACAGCATTTTGGGGAGC TACAGGCTTGGGTGTGAGTGACTTGTGTCTCTGGGTGCTGAAGGCCAGAGGGTGCAAGGG CCTGGACGTCGAAGTGTGTCCTAGGGACGCAGAGGCTAGCCAGGGGCAGAGTCTTTGCAG TGTGGGCCTTTGGTGTCCAGGGAACTGGAGTCGGAGGCTGGTTCAAGGCCCCAACCCAGG GTAGACAGCTATGGACACCCTCACTGAGGGAGCAGGCAGGAGAGACGGGGATGCTGGGAG CTGCCTTCTGCTCAGGGAGGCACCTGCACCCCCTACCCAGTCTCCAGCCCCCTAGTTGGG CAGCAAGGGTTAGAGGATTGATCTGAAAAGGAAGAATGCCTGTTGGGAAGGACTAGTTTG GAGCCAATTAGGGCCATGGCTGCTGGGGGTGGGGGCTGCAATTCCTGACACACTCAGGAA CCCCTTCTTCCAGGAAAGGGTAGGAGAGGCAGAGGTGCAAAATGGGCCTGAGGGTCCCGG GCGTACCTCCGCTTGCCTGCTTTGGGCCTGAGGTAGGATGGGGGAGGGGATGCCCAGGGG CCTGTGAGCCATGAGTGCCGTAGCCAGGGAGCTGGGCGGCTGCAGACACACCTGTGAAGA CGGCTGGTCCCTCAGACATACAGCATGTTGGGCAGGGGAAGGGGACACAGCCGCACCTCA CCCATGTGCCCACCTGACACACAATCCGACATGGACCTGCACGCACAGGCAGGCAGCTCA CAGAGTTCCCAGGCAGGTGTGCAGACAGCCGGCAGCCCCCTGTCTGCTGTCACAGACCTA CCCGGGGCAAGAGGCCCAGTTCCCTCCTTTCAAGCAGCTGGTGCTGGAGAGGGCTCCTCT GGGCAGCCCGCTGCCTAGCCTTGGGTCTCTGTTTGGATTTGAGCGGCCCCCTTGAGGGCT CCCCCAGGAGTGGGGAGCACACAGCCTGAGCCCAGCGTCAGTCTCTTCCGACAGTGCTTC CGTGAGCATCTCCTCCCCACCCCGTGGCCACAGCCAGGAGATGCCCCCCCACCTGGGGCT CCCAGGTCCCTGCCCTGCGTGAGGGACGGCTCAGATCCAGGCCTGCCTCTGCCAGTCCCT CCCAGGCCTGTCCCACACCCTTCCCCTAGGAAGCAACTCCAGGGGCCCCTTCTTTCCAGC CCCCATGTTTCTTACTCAGAGGCTGTCTCCCCCAAGCCCCATGCCAAATCCGCAGGCATG TGCACCTCATGGTCACAGATGCTCCGGGGCAGAATATGAGTGTGTATGTGCCTTGGGGAC CCTGCACAGGGGCCCTGCAGGCCAAGCACCTTCCAAGAGGAGGTGCTGTCAGGGGCCGAG TTTTCAGATCTGTGTGCTGTGGCCGAGGTCTCTAGTGTGGAGGAGGTGTGTTCTGTCCTT GGGCAGGGTGGGTGGCAGGGAAGCTGTCCTGGTCCTCAGCACCCCCATCAGCCACTCCAG ACCTGCCCTCCAGGTGCCTTGGGGCGTGGCTGGGGTGCCGGTGTGTCCCCACGCCCGACT CTGCGCATCACGGGGCTGAGGCTGGTATACAGCCTGGGCTCCATTCCCAGCCAGCCCTGG CCTCCTTCCAAGGGGCAGTCTTCTGGTCCTTGCTTCCCTCTCTTCCCCATCCCACAGACA AGAAGCAGAGAGCAAAGCATTGTGTCTTCTCCTCAAAAGAAGGGAGGTGGGAGGCCGGGT GTGGTGGCGCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGG TCAGGAGATCGAGACCATCCTGACTAACACGGTGAAACCCGTCTCTACTAAAAATACAAA AAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAG GAGAATGGCATGAACCCGGGAGGCGGAGCTTGCAGTGAGCCCAGATTGTGCCACCGCACT CCAGCCTGGGCAACAGAGTGAGACTCCGTCTCAAAAAACTAAAAAAGAAGAGAGGTGGGA GAGGAGAGGCTGTCAGAGCCTCTAAGCCCTGGTGCTTGGGCTGCAGAAGGGCAGAGCTAA GCGGGACTTCCCAGCACAGCACACTCCGGACAGGCTGTGGCTGTTGAAGGGACCCCCGAG CTCCAGCTGACACGCGGAGGCCCGGGCACAGACAGGCATCATACCTTCGGCCTTGGCCGC ACTCTGTGGTCATTGGTGTTGGGGGCAGCCCAGGGTCAGGGCAGGGTCTCAGCCTCGGAC CCCAGGCCCCACCCCTTGCCCAGCAGTGCTGCGTTTTCCCAGTGAGCTGTCGTGGAGAGA GCAGAGGGGACCCAGCGCAGGCCCAGTGGCCGGTGAGGGGAGACGTGGCTCTGGGACGGG GGCCTCCACCTGGGTGGGGGGATGCTCCAGCTTCCAGACCCTTGGGGAGGGGGCACTGCC CAAACTAAGCTGGCACTGGGGCTGTGCATTTGAAGGTGATGGTGGTTCTAGGTCTGAGGA GGACACCCTCCTAACAGCCTCATCCCCAAGCTCCGGGCTGTGTTGTGGCAATGGGAGGGA GGAAGTCTGAGGAGACCCTGGTGACTGAACGGAGGAGGGAGTGAGTTAGACGCTCTCAAG GGCTCTGCCACCTCCCGGAGCCAGCGGCCTGTTACTACATTTAAAAAAGCCTCCCGCCCA CTGGAAAATAATCAATAACTTTCCTTTATCCCTGGGGGTGGCAGGACCTAGAAACACTGG AGGAGTCCGGAAGTGCCTGGGGCTGGGCCGGCGCTGGTGTGCTGTGCAGGGTGCCGCGGG CACGTCCGCCGCGTGTGTGCGTCAGCTCGGGGCTCGGCTGTGCTCTGCAGGGACCACAGC GGGCGTGTCTGTGCTCCCACCCGAGGCACCCACAGCTCCACACGCTCGTTCCGTGGGTGC AAAGGAGATGGGAGAAAGAAGCCCTGTGAGAAATGCGGGGCAGGGTTTGCGGAACAGGGG ACCTGGGCTGGTGAGGGCTCCTCGTCTGGTGACCTGTGAGCCCCGGGGCCTGCAGTCTGC GAGGGTTCAGCTCAGACAGTTGCCAGTGGCCTTGCACCAGGCTGCAGCTGCCCCTGAGCC GGGCTGTGCGTGGCGCTGATGAAATAGAAAAGGGCATTCGCTTGTCAACGTTGGCATCGG TGGCAGGGTGTGGTGGGCAGAAGGGTCACAAAGTACGGGTGGGATTGGCAGGCAGATACA CGGAGGGAACGTGCGCATTTGAGTGCACGTCCACCAGCACCAGCCCCAGGCCACAGGCAG ATCCCAGGAGACACGCAGGGGCCCTAAGAAGGGAGCTGGGAATGAGGGGCCACACAAGCC CGGGACGGAGGCCTGTCGCACATGGGGTGGCCCCGACTCAGGCCCTGGAGTTGGCCAGGA CCCTCTAGCATCCTCAAGGGCTGGGCCAACCAGGCTGGCGTGGGGTGGGGCAGGGGAGGG CTGAGCCAGTGGGCGTCGTCTGTAGGGGGATGCCCAACTGCGGCCCCGTCTCTCGGCTCT CCTCTGGGTCTCTGGCCAGCTGTGGCTCCTGCTGGCCCCAGGCGCATCCCAGAGGCAGGT AGAGGGAGGATGGCTGCTCTGAGGGCACCTCTGCCGTGCTTGGGGCTCGGCCTGGGGTGC GAGACCAGGGCAGACCCCCGGGAGATGGAACGGCCCGGTCCAGCCCCACCTTCCTCTCCT CCTGCCCCACCTTCCTCTCCTCCTGCCCCACCTTCCTCTCCTCCTGCCCCACCAGAACCG GGGGCGGCTGGCAGACAAGAGGACAGTCGCCCTGCCTGCCGCCCGGAACCTGAAGAAGGA GCGAACTCCCAGCTTCTCTGCCAGCGATGGTGACAGCGACGGGAGTGGCCCCACCTGTGG GCGGCGGCCAGGCTTGAAGCAGGAGGATGGTCCGCACATCCGTATCATGAAGAGAAGGTA CTTGGACCAGGGCCGGACAGGAAGGCGCAAGGCTCAGATGGGGCTGGAGCTTCAGGCCTT CAGCTGCTCAGATGAGAGTGTCCACACCGGCCTCCCACACCTTCCCTCAGATGCTGGTCT TTTTGGGGTCCTGTGTGGGTCGCAGGCAGGAGCTGTTTCCTCATCTGCCCCCTGTCTGGC GTCCCCTCCCACCTCTGCTCTGCGGCGCTCACTGGCAGAGGCAGGTTGGCAGCAGTTGGG ACCCAGAGGTCTGCACCTTCCTGGGCCGACGCTCCAGCTACCCTTGCTGACCGGGTCCCA GTCTGGCCAGAGAGCAGCTCTAGCAACAGGGAGCTCCATTCAGGCTCGTGACTGGCTGTG CAGAAGCAGCCTCGGCCCCCACCTGCGGTACAACAGGAGGGCTCCTCTGAGTGCACGGCA ACAAGCAAGAGGGAGAAGGGGCCTCGGTCCTGTTCTTCCTGATGCGTGTCTGCTGAGGCC AGGAGCTGGCTTTGGCCCATGGGCCTGTCCTAGTGGGAGGCCCCAGCATGTTGAGCCAGT AGCAGGTGGTGCTGGGCATGGCAGCCGCCCTCGTTCACTGCCCAGGGCTGTGGCCCAGCG GGGCACTGACCCGAGACAGGTCTGCGCACGCCCTGCTATCCTGAGGCTGGGGTCAGGGGC CTCCAGAGCAACATGGACCTTCTGCTTCCCTTCCTGCAGAGTCCACACCCACTGGGACGT GAACATCTCTTTCCGAGAGGCGTCCTGCAGGTAGGAGCCGTGCTGTGCGTGCATAAGAGG GGGCCGTGACTCCCCTCCCTCCCTCCCACCCCTGACCGTGCCCTGCTGTCTGCTGTCCGC TGTCTCAGCGTGAGCTGATGCTGTGATGCTGGCTGAGTGTCTGCCAGGTTTGACATGTGC TGCAAGGTTGTCCCCCATCCCGGGAGGCAGACAGTGTTGCACCCAGTTGGGACTGAGGGA CCCCAGACCCAGTCAGATGCAGCTCTCGGCAGCAGCTCAGGTGTGAGTTCTGGGCAGCCC GGCCCTGGAGTTAGAGTGCACTTCCTCCCATGTGAGACTGGCCATTTGAGCCCAAAAATG AGGCTGTCACCTCCCCCTTCCCACCCTCCTAGAGACCCACAAGGAGGTGAGAATGCTGAT GTGTGAGTGGGGCCCTGAAGGGTGTGTAGGAGCTCTAAGGCGAGGGGATGTCTGCAGAGT AGAGGAACAGGGAAGGGCGTGTAGGAGGGACGAGGAGTGAACCTGGCAGCTCTGGTTCAG TTGGATGCTGAAGAGTCATGGATGCTGGGCCTGTGGGCACCGTCCTCCAGGCGGGAGCCA CCGAAAGTTCTTGAGCAGGGCAGTGACCAGGTGTATGTTTGGAGAAGGTCCCTCTGGAGG CCTTCCTGGCAGACAGGGGATTGGATTCAGGCTGTGGAAGCAGGACGGTAGGGGGTGTGA TTCCAGGATGTGGAAAGGAGATAAAAATGAAGAGCCCCGGGGAAGAGGTCAAGGGAGTTG GGGGACCCGAGTTCCTGGCTCCAGGGGGAAGCGAGTGGTAAGTCTGTGAACAGAGCCCAG CTGTGGATTCTGTCAATGGGGTCAGGTCTCACCCTGTGGCTTCCAGGGCAGCAAGGCAGG AAGGAGGCGTCTGCCACAAGGCCAGCTTCCTGGGGCCAGAGCCGTGAAGGCCCAGGGGAC CTGCGTGTCTTGGCTCCACGCCAGATGTGTTATTATTTATGTCTCTGAGAATGTCTGGAT CTCAGAGCCGAATTACAATAAAAACATCTTTAAACTTATTTCTACCTCATTTTGGGGTTG CCAGCTCACCTGATCATTTTTATGAACTGTCATGAACACTGATGACATTTTATGAGCCTT TTACATGGGACACTACAGAATACATTTGTCAGCGAGGCCTGTAGGGAAACCCAGCCGCGG TCCCCCCGACCCCGCTCCAGTAACGGCTCCTCCTGCCTGCAGCCCCCTCCTCCGTCTGCC TGGCCTCGGGAATGCAGCGTCCCTCGGCAGCACTGACGGCAGACAGCCTGGGGTGCCCTA GGAAGAGGCCAGGTCTTCCATCCTGCACGGGCCCTAGAAGGGGCTAGGATGAGTTTCTGA ATCTCCCAAGGGCGAGATTTCGGTCAGAGGGGAGGGCGTGCTGGGGTCCCCGGAGGAGAA GGCCCAGCACACGCCTGAGTGGACTGAAGCCTCCGCCTGTTGACCTGACCCTGGTGTCCG GTCAGAGCGGGTGGTGGTCCCTGAACCCACACGGGCTCCCAGACCATGTCTGTGTTTCTT TCAGCCTGTCCCTGGGTCCTTCTGCCTCTGCAGGCTCCCACAGAACACACTGCCAGGCCA CCTCCATCTGTGTGTTCATTTGCTCCCGTCCAGTGGTCTCCACCCATCTGTCCGTCTGTC CTTCCATCCCCTTCGCCCTGTCTGGCTGGCTCTGCAGTGACCACCTGCCTTTTGGAGCCA GCGGAGCCCCAGGCCGTCCTCCTCTGCCTCAGGAACCCGGGGTGGCAGATGCTCCTCGAG CCATTGTTTGCAGGCGGGGGCTTGGCCCCTCTCTCCTGGGCCCCTGAGCTGGTGGGAAAA TGGGCAAGGGCTAGGCCGTGTGGTCATCAATGAGGGGCGGTGGCGGGAGGCCCATGCGTG GGCAGCTGGGGTCACACCTGCCAGGCTCTGGCCTCCCCCTCCCCCTCTCCTTCCTGCGCC TCCTGCCCCAGCCCTGACTGCTTCTCCCAGCTTCCCCACCTCCTGACCTGCAGCCCGGCC CCACCACAGAGACTCTCAGGGGCTTCGTCCCTTGTGCGAAGCAGGGTGCAGAGGGCATTC TGTGGTTCGAGGACCATGCGCTGATGTGCCCGGGCCGGGTTCCTGCTTCTCCACTCTGGG ACGTCCAGGGCGTGTTTCTTTACATAAAACTGGCATAACTGGCTCACTGAGTGGCCAAGT GACCAGAACAGGTTTTCAGGGGCCGGGCCAGGCCAGGCTGTGTCGGAACCTCAGGAGCAA ACTCCAAGGCAGAGACCAGGGGCGGGGAGGGCAGGTGGCACCCAGCTCCCCACCAGGTGC CACTGCCCAGCCACAGCCCCTCCACCCAGCTATTAGGCCCTCCCTCACTTTCCTTCTGGG CGCCAGGCTCGGGGCTCACTGCCAGCCCCCAACCTCTGGAGTCTCTGGGAAACTAGTTCT CCTCCTGCAGGCGTCCTGGGGACACCAGAGGGGGGACCCCTGGGGAGAACTCCATGGCAG CTGTGGCTACTGCCAGGCCAGCCCTCAGCCCCCACCCCATGCTGAGGCCAGCAGTCCTCT CCTGACACCCCCGCGTCGATTAGGATCATGGAAGGGATGAGTCTCGCTGCCGATTAATCC CATAAAGTACTTACTCCCACCCAGCTGCCTTCCTATGTGCCTGGGGGGGGCTTCCTTTCC CACTGGGAGCCGGTGGGGGTGGGGGAGAGCCGTCATCTAGGTCTCCTGGAAGGTTTAGAG CCCAGCCTGGGAGTCTTTGGTGCTGAAACGGATCTGCTTAGGGGCAGCCTTGGATTAGCC CAGCTCCAGCCAGCCCAGGTCAGGGGAGCCGGGAGCTATTTAACGAGGTTTAGGGTAGGC TCCTAGGTCACTGCGCAGGACTGCTCCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTAC AGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGT GGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTCCGTTACAGGTGGGC AGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGG GAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTCCGTTACAGGTGGGCAGGGGAGG CGGCTCCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGC TGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTGCG TTACAGGTGGGCAGGGGGGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTAC AGGTGGGCGGGGGAGGCGGCTCCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGT GGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGGGGCGGCTGCGTTACAGGTGGGC GGGGGAGGCTGCTCCGTTACAGGTGGGCGGGGGAGGCTGCTCCGTTACAGGTGGGCGGGG GGGGCGGCTGCGTTACAGGTGGGCGGGGGGGGCGGCTGCGTTACAGGTGGGCGGGGGAGG CGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTCCGTTACAGGTGGGCGGGGGAGGCGGC TGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTGCG TTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTCCGTTAC AGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGT GGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGGGGCGGCTGCGTTACAGGTGGGC GGGCGGTGCTGCAGGAGGACTGCTCAGGGAGTGGCGCCTGGACCCTGAGCCCCTTCTCTG CTGACTGGGGAGAGGCTCACGGAACCGGGAAGGGGTGGAGGGCCGTGCTCCACACAGTTC GTCTCATTGCTCTCTGGGACTCTGTGGATGTGGGATTGGGCTGAATTAGCAAGAAGAGGA GAAATGAGGGAAGAAAAGAGTTAAATGCATGTTGATTCCAAGCCCCCGCCTGCCGGGGGG ACAGCGGGAGGTTGGAGCACGCAGCCCTGGTGCCTGGTGCGAGCTGCACGTGTCTGCCGG TGCCGTGTGTGCGTGGGGCGCGTCTCATCAGCTGCAGGACTGTGGTCTGGGCCTCAGTTT CCTCGTGTGCAGAAATCGGGGGTCAGGGGATGGTTCACATGTGGCACATTCTCTCCTGGG GCCTGTCCTGCAGGACTGCCCCTGAGCAGATCGGCCTCTTCCCGGGCGCCCGGTGGGCCC CTCGACCCCCTTTGAGGCAGGGAGTGAGATAACTGTGATTCCCTGTGGAGGGCGTGAAGG CAGAGCCGGCTGGCTGCTCCACATAGACCCTCCCTGGAGCAGCCGTGGGGTCCCAGGTCC CAGTGCCAGGTTCTGTGTCGCTTTGACTCGGGTGCTGCGTGGGTGTGCACACAGTGGCGT CACGGGCCACATGCCGAGGCGTGGGCACAGCAACGTGGCACTCAGAGGTCATCCCCACGC TCACACACAGAGCTAGGCACTCCCTGTGCCCAGGCTGGGCTCCAGCCTCGCAGCTGCCCA CGGGGTCAGCTTTTCCCGGTCTCGTTCTGCAGCCAGGACGGCAACCTTCCCACCCTCATA TCCAGCGTCCACCGCAGCCGCCACCTCGTTATGCCCGAGCATCAGAGCCGCTGTGAATTC CAGAGAGGCAGCCTGGAGATTGGCCTGCGACCCGCCGGTGAGGAGCACAGGGGGCCTGAG GGCGGGGTCGGGGCTGTGGGGCCAGAGGACGGTGGCGTCTCCACTCAGCACCAGCAGCCT TGGCAGGCAGCCAGAGAGGCAGGAGGAGCGGCCTGTCCCCCAGGGGCTGCATGGGATGGT AATTGTGTTAATCCCAGCCAGCGGGGCAGACAGGAGGCAGAGGCGGTGGCTCCGCTGTGG CTGCCGCTGGGGTGGGCTTGGAGTAGCCGGGGCCCTGCCACCCCCTTTCCACAGGGCAGA CGTAGGCGTGGCCTCAGAGGTTCAGAAACGCACACCCTGGAGGAACGCACGCACTCCCGC AGCGCACGCATGACTGGTCCCGCCTCCTAGGGCTCCTGGACGGAAGGGGTCCCCGGTCCC GCCTCCTAGGGCTCCTGGACGGAGGGGGTCCCCGGTCCCGCCTCCTAGGGCTCCTGGACG GAAGGGGTCCCCGGTCCCGCCTCCTAGGGCTCCTGGACGGAAGGGGTCCCCGGTCCCGCC TCCTAGGGCTCCTGGACGGAGGGGGTCCCCGGTCGGTCCCGCCTTCTAGGGCTCCGGGAA GGATGGGGTTCTCGGGAGGGAAGGGATCCGGCGCCTGAGGGAGGTGCTGCTGCCTGGTCA CAGTTGTGGGGGGACCAGGCCCCCCTCAGAGGGCACTGCTGTAGAGAGGGGCACAGCAGA GCCTCAGCCCCAGGGCAGGCCGTGAAAGGAGGCGGGGGCGCCCCGAGGCCCTGTGGACCC CAGGCAGGGGTGTTCCCAGCAGGGCCTGCATCTCTTGGGAAGGAGGGGTGGGGGAGGCCC ACCCCCATCTGTGTCCCCCATCCATGGCCCCCATCCGCGTCCTCGTGCACCTAGGAAGGC CCTTGTGGGGCTGGGTGGGGGCAGCTTCTGATGCCGCGTTGGAGACAGCTGAGAGGCGGT TGATAAAATCTAATTGCCCCATCGATCCAGCAGAGCGGAGGGAGCCCCACAATGATTGAG ATATTCTGAGCCAGCAGGCCCTCCCCTGTGCCTTCACACAGGGAGACCTCCTCAGGTACA CGCGTGTGCGTGTGCCGGCATGTCTGTGTCTGGGGTCCTGTGGGGTGCACGTGATGGGGG TTGCCCGGCAGCTCTCACCCATGGAGTCAGGACGTGTTCGTGCACTTCCGGGCTCACAGG CTCTACGGGGCCTCACGTGTCCTGGACCCGTGTCCAGGTCTCCCATACGCACTCCGTGTC AGGGTCTGGCCCGCTCCCCGGAGCCTCCTCTTGGAGGGGCATTCACCCTGGGGGGCGTTC ACCTCTTCTCCCTTCCTGTGACCCCAGGAACCACACATCCATCCTGTTCCCAGCCCGGGC CCTCCCGCTAAGCCGCACCTCCCTGGGCCCTGGGCTGTGAGGGACTCAGAGCAGGTCCTG CATCTGCCTCTGTGAGACCCGCTGGGGTCCATGAGTGAGGAGTGAGCATGGCCTCATCGG CCTTCCTGCGGTCTCATTGCAGGCCCCCTTCCACCTGCCCCCCCCCCCACCCAGTCACCT CCCCCAGGCTAGGAGGAGGCCTTAGCCCCCCACAGAACGGAGAGGGTAGTTTCCACTGTG TACAATGGAAAAGTGATTGCCAGGAGGTGAGAGGCCTTGCTAACCCTGAGGGCATGTGCA TGGTGGGCCAGGTGGCAGGTGTGGAAAAGAGCCAGGTTCCCCCAGCCTTGGCCCACCCCC TCCCAGCCCACCGAGCTCTGGCACGGGAGGCTGTGGGGGAGACGATGGCTTCTCAGGGGC CTGAGCAGTGGTGCCTGGATCCGTGTGTGGCCAGGTGCCCCCCGCCGCCCGCCGGGCCCA GCCACCCGATCTGTCACCGAGGTGGGGACCCTGGACCAGACCGTGGGACTGACCCTCTCT CTGGGGCCGGGCCTGACAGCAGCCGGGCCAGGATCAATAAGTTATTAGCACCACTCTGTC AGCTGTAATGTGGGATTGATCGGTGTGGCCGCCGCACTTCCCCAGCCTGATAAAAATGAC AGATTAAGGGAATAAGAAAAAGGAATTAGGCCTGGAGCTGACGGCAGGGCTTGTGGGGGG ACGGGCTTGGGAGCCCCACTGCCTAGGCCTCATGGAGGTCTTGGGTCACAGGGGAGTGGC CCCTCACTCCACCCAGCTAGAGCCCTCATGAGGATGAGGAAGGGCCAGAGTCGGAGGCAC TGGCTGGCCTGGGAGACCCCCAGGGCGTGGAGTCAGGGGCTTCGGAGGAGCTCGGGGTGG GTCGGAGATGGGTACATGGATGGTGTGGTCTGGAATGGGTGCGGTCGGCAGGACCCAAGG GAGGACCTCAGGAGAGTGAGCTGGGCCTGGCCTGGGCCTCCCCTCTGCCACCTGCTGGGC TGTGTTTGGGGCTGAAGCTGGACCTGGCCTGGGCCTCCCCTCTGCCACCTGCTGGGCTGT GTTTGGGGCTAGGGCTGGGCTGGCCTCGTGGCTGAGGAGGTGGGTGAAGCTACTGGGAGG TGCACCCCAGAAGCCCAGAGCCTGGCTGGGCTGGTGGACAAGGGCATGACAGCCACGCCA GGGTGCTAGCTCAGGCAGGACTGGGCCAGAGAGGAGGACGTGGGCCTTCTGGGGGCAGGG ATGGGTATGACCAAGTAGGAGGCCTGGGAGTGGAGGCGCCTCGAGGCGGCCTGGGGGGCC CACAGCCCAGTGACTCACAGAGCAGCAAGAGGTCAGGTGTGAGGTCCTTCCCGGCTTGTC TCACCCCACGCTGGCATGTGACCCTGCACAGCCCGCCCTCACTCCTGTCCAGGAGGGGAA GGTGGTGCCTGGTCAAACCAAAAGCTTTTTATTCTCCTCTAGGGGGATGAGAGGGGGGCT CGTTAACTTGCACAAGAGGCTAGATGGCGGGTGGGGCAGCTGGGTGCCTGCTGTGGATCT CTTCTGCACACACGCACCAGGGCCAGTGTCAGAGCTCCCCTGTGCCCCTGTCCCGCCACA GCCAGGCGTGATGTCCTCTGCGCTGAAGGCTGGGGCTGCCAGGGCTGGGCAAGGCCTGTA CTCACCAGGACCAAGGGCCCCCTGAGAGATGGTGGGTGCGGTCCAGGCTGAGCTGGAGCA GGGGCTGGGTTCCCCTTCCATTCCTTGAGATGCAGGTGGGCACTCACTACCCTCCCGCAG GTGACCTGTTGGGCAAGAGGCTGGGCCGCTCCCCCCGTATCAGCAGCGACTGCTTTTCAG AGAAGAGGGCACGAAGCGAATCGCCTCAAGGTAAGAGCGTGGCTGGGACGAGAGACAGGT CACCAGGGGAGGGGGCAGTCCCTGAGGGTCCCCTGGACCTCGAGCAGGCACTCTAGAGGG GCGTGGTCCTCGGCAGTGCCTGGAGAAACCTCTCACCCCGGGTCCTCCCCAGCAGAGGCG CTGCTGCTGCCGCGGGAGCTGGGGCCCAGCATGGCCCCGGAGGACCATTACCGCCGGCTT GTGTCAGCACTGAGCGAGGCCAGCACCTTTGAGGACCCTCAGCGCCTCTACCACCTGGGC CTCCCCAGCCACGGTGAGGACCCACCCTGGCATGATCCCCCTCATCACCTCCCCAGCCAC GGTGAGGACCCACCCTGGCATGATCTCCCCTCATCACCTCCCCAGCCACATGTACTCGGC CATTCCTGTTGCTGAGGCCCTGCTGACACCAAGGCCAGGCTGGATGCAGGTCCCTCTGCC ACACGTCCTGCCCCATGCCCCCTGGGGCGGGCCACACCTCCATGTCCCCTAGGTCCCCAG GGTCATGACTAGCTCACATTTTATATAGAGAGAAATGGAGTCTGGGGTGGACCCAGGTGA GGGTGGGCAGTGGGCATGTCAGCAGCACCCCCCGAGGAGAGCAAGCTCCTGGACCCTGTG GTCTGTGAGTCGTCTATGCAGCCAGTGGACGCCGACCTGCCAGACGCCTGCCCCAGGAGC CTGGGGAGGGGCAGTGAGCAGAAAGGCCGGGCTGGGTGCAGTGGGCACTTGGCCACCAGG ACTCCCCAGGTGCTGAAGAGACGCCAGCTGGAGGGGCTGCCCCTTCCCCCGGGTCGGCCC TGACCCTGTCCACCCCACCTCAGGACGTTCTCCAGGGGTCCCTCCGGGATGCACTCGGAC CCCCTGCCCGCTGCACTCAGCCTCCCAGGCCCCAGCCGCCCGCCTGGCAGGGGAGCTTGG CTTTTCGGGCTAGAGGTGGGTGGGGGCGCCGGGAAAGGAGGCAGGATTCCTCACACCAGG CACCGTCCCCCAGGGCAGCTCAGGCACCAAGAGCCTGAATAATTCACCAAATGTTAATAA TGTAAAAATCCTCCTTTTTAATTGCTTTCCCTGCTCTGCCTGGGGCCGCTCTGCTGGCCG CGCGGGGGAGGGGCGCCGGCCGCCGGGGAGCGCGCTGTCAATCAGGCCGCGCCGCCGCCC CCCCCCCCCGCCCCGCCGCGGAGCCGGCCGTAAATAACCCTGTAACTAACCCGGCCGCTA GCGCGGGGGCGCTGGGCCCCGCTGGGATCGATGCGGGCGGCCGCGCCGGCTGGGCTCTGC GGGCTGGCACCCGGCCCGGGGCGGGACCCACCTCCGCTTTCGGGTAATTAATTTATAAAC AGAGGCGGCGGTGGAGCTGGCGGAGCCTGCATAGTGGGGGCTGCGGGGACTCGGGAGGCC CGGGCGGGAGGGAGAGGCCGAGAGACCTGGGACGCGGCGCCTTAGACGCGGGCGCTGCGT GCGCATTGGGGCGAGTGTGGCCACGCGGGACAGTGACCCTGCGCAGCCGGGACTGGGCGA CCCCTGTGCTAGTGTGGCGTGCGTGCGCGGGCGCTGCCTTGCCTTTGTGACAAGCTTTGG CCAGCCGCGTCTACTATGGGGACCTCAGATTTTCTTGCCTCCCACCGAAGAGGGGGTCCC CTGGGCGGTCAGCCCCTGGCTGGCACTTCTGGACTCTCTCGCTGCCCCGCAGGCTCTGTG GCCTCGGGACGTCTGCACAGCCCCCTCCCCGCAAGGCTCAGCCGCCTCTCAGGCCGGAAG CCTCCAGGCACCCGGCTCCCCTTCGGGGAAGAGCTTTTCCCGACACTTCCTCGCCCAGCA TCTTGTCTGCCGTCTCGGCCCTGTGGCCGCCCATCCTCCTGCCCCGTGCCCGAGACCAGC CCAGGGGCCGAGCACGGCCGAGTGGTGTGGTCAGTTCCCCACCTCAGTGTTCTACGCCAG GACGCGGGCTGGGGAGGATGAGGGCGCATAGCCGGGGGGATCACTGCTGTTGTCCCCCAC CCAGATCTCCTGAGGGTCCGGCAGGAGGTGGCGGCTGCAGCTCTGAGGGGCCCCAGTGGC CTGGAAGCCCACCTGCCCTCCTCCACGGCAGGTCAGCGTCGGAAGCAGGGCCTGGCTCAG CACCGGGAGGGCGCCGCCCCAGCTGCCGCCCCGTCCTTCTCGGAGAGGTACTGGGGTGGC TGCCGTTCTCTGCTTGTTTCTGGGGTGCCGCCCGCACCCCCGCGCTCTCAGCCACCAGCA CGCGCCCCGAGAGTGCCAAGCACTGTGTTCAGCTCTAGGTTCGGGTCCGGGCAGAGCGTT TCGGGGGTGACACCGATCTGGGCTGCAGTGTTGAGGGCGCCACTGGGGTGCGTGAGGGAG GCTGAGGCCCATCAGGGGGTTCCCTGGAGGAGAAGCCAGAGAAGGGGAGAGCTCCAAGTC TGGAACCCCGGGGTCAGTCGGGAGGGGTCGGCCAGAGGACTCAGAGCTGGAGGCGGAGGG GGGGTCCTGGCTGGCGCTCAAATGTAGACGCCGGCGCCGGATCTGTTCCCGGCACAGACA AGGCCTCCGGCACAGACCCGGGTTTCTCGGGTCCAGGACACGAGGCGGGGCGGGGCGCCT GGAGAAGGGAGGGGCCGCCTGAGGCCCGAGTCCCTGCCCGGCCGCTGAGCCCGGCGTCTG CAGCTGCCTCCACCGCCGCCCGGATTGCGGCTAATGACGCCCCCGCTTCCCCCGCCGCTC GGGTCCGCAGGGGAGGGGAGCAGGCGGGGCCGGCGCCCCGCGCAGTAATTACCGCTGCAG CCGTCGCCGCCCGCCGGGTCAGCGCCTCCGCGCCGCCGCCGAGATTAATTGGCGCCGCCG GCGGGGGCGGGGATGGCGCGCGACCTGGGGCCGTAACGAGCTGCGCATCGACCGCCCGCG GGGCCGGCAATTAGCGGAGGCGGCGGGGGAGGGGCGCCGGGGCCTTTACGGGAACGGGGG CGGGGGGGACGCCGCTCATTGCGCTGCCGTCCACAGGGAGCTGCCTCAGCCGCCCCCCTT GCTGTCGCCGCAGAATGCCCCTCACGTCGCCCTGGGCCCCCATCTCAGGCCCCCCTTCCT GGGGGTGCCCTCGGCTCTGTGCCAGACCCCAGGTGAGGAGGCGGGTGCGCATCCCCTGGG AGCCCGCGTGGAGGCTCGCGGACCCGGCCCTGCCCCTGTCGGAGCCGAGACGGACCGGGT AGGGGATTGCAAAGGGCCGGCTCGGACCGCCTCGGACCCCCCGACCCCGCGTTGTCCCCC TCCCCACCAGGCTACGGCTTCCTGCCCCCCGCGCAGGCGGAGATGTTCGCCTGGCAGCAG GAGCTCCTGCGGAAGCAGAACCTGGCCCGGTAGGTGCGGGGAGGCGGGCGGGGCCGCGCG GCCCGGGAGGCGGCTGACCCGCGTCTGCCCCCGGCCCAGGCTGGAGCTGCCCGCCGACCT CCTGCGGCAGAAGGAGCTGGAGAGCGCGCGCCCACAGCTGCTGGCGCCCGAGACCGCCCT GCGCCCCAACGACGGCGCCGAGGAGCTGCAGCGGCGCGGGGCCCTGCTGGTGCTGAACCA CGGCGCGGCGCCACTGCTGGCCCTGCCCCCCCAGGGGCCCCCGGGCTCCGGACCCCCCAC CCCGTCCCGGGACTCTGCCCGGCGAGCCCCCCGGAAGGGGGGTCCCGGCCCTGCCTCAGC GCGGCCCAGCGAGTCCAAGGAGATGACGGGGGCTAGGCTCTGGGCACAAGATGGCTCGGA AGACGAGCCCCCCAAAGACTCGGACGGAGAGGACCCCGAGACGGCAGCTGTTGGGTGCAG GGGGCCCACTCCGGGCCAAGCTCCAGCTGGAGGGGCCGGCGCCGAGGGGAAGGGGCTTTT CCCAGGGTCCACACTGCCCCTGGGCTTCCCTTATGCCGTCAGCCCCTACTTCCACACAGG TGGGCACCCCCACACTCTAGATCCTTCCAGAGGGCACAGGACTGGCAGGCCGCCTGTGGA AGGGTCTTGGGGGGAGGAAAAATTCCCCTTAGGCACCCATCCCCCACCTCAGCAATTGGG GCACACGACGGTCAGGAGACGGGCGGGTATGGGAAAGCCAGCCAGAGCCCTAGTAACACG CCCCACAACTCAGGCGCGGTAGGGGGACTCTCCATGGATGGGGAGGAGGCCCCAGCCCCT GAGGACGTCACCAAGTGGACCGTGGATGACGTCTGCAGCTTCGTGGGGGGCCTGTCTGGC TGTGGAGAGTACACTCGGGTAAGGGGGGGCCCCAGTTCCTGGGGCGGGGCTGGAGCTGGC TGGCAGTCACTACCTCCCTGGAAAGGATGGTGGGGTAGGGCCATTCCCCAACGCCCTCTC CCTCCCCAAAAGCAGTGCGCAGCAGGGACTGGACTGTGCACCCCACCTTTTTTTTTTTTT TTTTTTTTTGCCAGGTGTTTTCTGCCTGACACTCAAACCCAACAGATCACTGTTTTTAAA AAATTTCCGTGAGCTGCACAAACAGCTCCTCTTGGCTCTGCTGGGCTGGAGGATGGAGCA GCACCCGGGTCCTGACCCTCCCTCCCTCCCCCTTCCAGGTCTTCAGGGAGCAGGGGATCG ACGGGGAGACCCTGCCACTGCTGACGGAGGAGCACCTGCTGACCAACATGGGGCTGAAGC TGGGGCCCGCCCTCAAGATCCGGGCCCAGGTGAGACGCTGGGGAGTGAGGTCAGGGTCTC CAGACCACAGCTGGGCAGAAAGCTCTGGGTGGGTGTGCGACAGCCCCCACCAGGCCATCT CTCTGCAGGTGGCCAGGCGCCTGGGCCGAGTTTTCTACGTGGCCAGCTTCCCCGTGGCTC TGCCACTGCAGCCACCAACCCTGCGGGCCCCGGAGCGAGAACTCGGCACAGGAGAGCAGC CCTTGTCCCCCACGACGGCCACGTCCCCCTATGGAGGGGGCCACGCCCTTGCCGGTCAAA CTTCACCCAAGCAGGAGAATGGGACCTTGGCTCTACTTCCAGGGGCCCCCGACCCTTCCC AGCCTCTGTGTTGAGGTTGCCGGGGGTAGGGGTGGGGCCACACAAATCTCCAGGAGCCAC CACTCAACACAATGGCCCTGCCTCCCACCGCTTTATTTCTTTCGGTTTCGGATGCAAAAC AAAAAATTTTAAAAGAAAATGTGACTTCAAAGGAAAGGAACAAATTTTCAAAGACTTGGG GGAGTGAAGGCAGAGCCTGGTGCAGATGGACGAGGTCTGCAGACGGAGGGCAGAGGTGGT GGAAGGGGCCAGGGGCCTGCAGGCCTCCCCCTGGAACTGGGACTGGTCTCGGTCTGCTGA CGTCAGGGTCAGCTCCCCCGCGGAGCTGACTTCAGCAGCCCACAGCTGTGGGGCTTCAGC AGCCACACCAGCCCAGCCCAGCCCAGCTCTCGATACGTTTGGTCTTTCATGCTGAAAAAT AAATAATAAAGCCTGT bcftools-1.21/test/csq/ENST00000341065/ENST00000341065.fa.fai000066400000000000000000000000211467060157400215160ustar00rootroot000000000000001 19696 19 60 61 bcftools-1.21/test/csq/ENST00000341065/ENST00000341065.gff000066400000000000000000000077631467060157400211600ustar00rootroot000000000000001 ensembl_havana gene 1 19696 . + . ID=gene:ENSG00000187634;Name=SAMD11;biotype=protein_coding;description=sterile alpha motif domain containing 11 [Source:HGNC Symbol%3BAcc:28706];gene_id=ENSG00000187634;logic_name=ensembl_havana_gene;version=6 1 ensembl_havana transcript 5433 19696 . + . ID=transcript:ENST00000341065;Parent=gene:ENSG00000187634;Name=SAMD11-001;biotype=protein_coding;havana_transcript=OTTHUMT00000097860;havana_version=4;transcript_id=ENST00000341065;version=4 1 havana exon 5433 5457 . + . Parent=transcript:ENST00000341065;Name=ENSE00001768193;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001768193;rank=1;version=1 1 havana CDS 5433 5457 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 6160 6210 . + . Parent=transcript:ENST00000341065;Name=ENSE00002696520;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00002696520;rank=2;version=1 1 havana CDS 6160 6210 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 10893 11017 . + . Parent=transcript:ENST00000341065;Name=ENSE00002703998;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002703998;rank=3;version=1 1 havana CDS 10893 11017 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 14161 14250 . + . Parent=transcript:ENST00000341065;Name=ENSE00002686739;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002686739;rank=4;version=1 1 havana CDS 14161 14250 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 14396 14533 . + . Parent=transcript:ENST00000341065;Name=ENSE00001708361;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001708361;rank=5;version=1 1 havana CDS 14396 14533 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 16265 16427 . + . Parent=transcript:ENST00000341065;Name=ENSE00003477353;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003477353;rank=6;version=1 1 havana CDS 16265 16427 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 17257 17372 . + . Parent=transcript:ENST00000341065;Name=ENSE00003681266;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003681266;rank=7;version=1 1 havana CDS 17257 17372 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 17531 17609 . + . Parent=transcript:ENST00000341065;Name=ENSE00003675531;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003675531;rank=8;version=1 1 havana CDS 17531 17609 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 17680 18179 . + . Parent=transcript:ENST00000341065;Name=ENSE00002728091;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002728091;rank=9;version=1 1 havana CDS 17680 18179 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 18374 18498 . + . Parent=transcript:ENST00000341065;Name=ENSE00002733131;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002733131;rank=10;version=1 1 havana CDS 18374 18498 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 18819 18929 . + . Parent=transcript:ENST00000341065;Name=ENSE00002692620;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002692620;rank=11;version=1 1 havana CDS 18819 18929 . + 0 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana CDS 19029 19274 . + 0 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 1 havana exon 19029 19696 . + . Parent=transcript:ENST00000341065;Name=ENSE00001804027;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001804027;rank=12;version=1 1 havana three_prime_UTR 19275 19696 . + . Parent=transcript:ENST00000341065 bcftools-1.21/test/csq/ENST00000341065/ascii-art.txt000066400000000000000000000021371467060157400212630ustar00rootroot00000000000000 16257 16265 16427 56789012345 7890 CCCCACCCAGA-------------GGTACTGGGGTG CCAGA C-AGA CCCACCCAg CCCACC-AG ......ooXXXXXXXXXXXXXXXoo...... 09876543210 01234567890 CCC GGTACTGGG- CC- GGTACT-GGG -CC GGTACTGGGGTG T- 18374 18498 45678901234 890123456 CACAACTCAGG-------GGTAAGGGGGGGC ......ooXXXXXXXXXoo...... 09876543210 01234567890 Axx Cxx Tx 18819 18826 901234567890123456789 CCCCTTCCAGGTCTTCAGGGA CAGGTCT A ......ooXXXXXXXXXoo...... 0123 19029 19274 CTCTCTGCAGGTGGCCAGG CAGGTG---AG CAGGT---CAG CAGG---CCAG CAG---GCCAG ......ooXXXXXXXXXoo...... 19030 GTGGCCAGG -V--A--R- 509 GTG---AGG -V-----R- GT---CAGG -V-----R- G---CCAGG -V-----R- 19026 V A R cagGTG.GCC.AGg cagGT-.--C.AGg V-R cagG--.-CC.AGg A-R cag---.GCC.AGg A-R bcftools-1.21/test/csq/ENST00000341065/ascii-art.txt-l000066400000000000000000000021371467060157400215140ustar00rootroot00000000000000 16257 16265 16427 56789012345 7890 CCCCACCCAGA-------------GGTACTGGGGTG CCAGA C-AGA CCCACCCAg CCCACC-AG ......ooXXXXXXXXXXXXXXXoo...... 09876543210 01234567890 CCC GGTACTGGG- CC- GGTACT-GGG -CC GGTACTGGGGTG T- 18374 18498 45678901234 890123456 CACAACTCAGG-------GGTAAGGGGGGGC ......ooXXXXXXXXXoo...... 09876543210 01234567890 Axx Cxx Tx 18819 18826 901234567890123456789 CCCCTTCCAGGTCTTCAGGGA CAGGTCT A ......ooXXXXXXXXXoo...... 0123 19029 19274 CTCTCTGCAGGTGGCCAGG CAGGTG---AG CAGGT---CAG CAGG---CCAG CAG---GCCAG ......ooXXXXXXXXXoo...... 19030 GTGGCCAGG -V--A--R- 509 GTG---AGG -V-----R- GT---CAGG -V-----R- G---CCAGG -V-----R- 19026 V A R cagGTG.GCC.AGg cagGT-.--C.AGg V-R cagG--.-CC.AGg A-R cag---.GCC.AGg A-R bcftools-1.21/test/csq/ENST00000341065/frame1.txt000066400000000000000000000004431467060157400205600ustar00rootroot0000000000000019030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding 19030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame1.txt-l000066400000000000000000000004431467060157400210110ustar00rootroot0000000000000019030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding 19030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame1.vcf000066400000000000000000000005671467060157400205260ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 19030 . TGGC T . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame2.txt000066400000000000000000000005331467060157400205610ustar00rootroot0000000000000019026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding 19026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame2.txt-l000066400000000000000000000005331467060157400210120ustar00rootroot0000000000000019026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding 19026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame2.vcf000066400000000000000000000010171467060157400205160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 19026 . CAGGTGGCCAG CAGGTCAG . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding;type=first is X, so 508V is correct bcftools-1.21/test/csq/ENST00000341065/frame3.txt000066400000000000000000000005651467060157400205670ustar00rootroot0000000000000019026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding 19026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame3.txt-l000066400000000000000000000005651467060157400210200ustar00rootroot0000000000000019026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding 19026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/frame3.vcf000066400000000000000000000010031467060157400205120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 19026 . CAGGTGGCCAG CAGGCCAG . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding;type=879285-CAGGTGGCCAG-CAGGCCAG, correct is CAG---GCCAG, first codon deleted, synonymous acceptor bcftools-1.21/test/csq/ENST00000341065/not-a-start-lost.txt000066400000000000000000000002211467060157400225270ustar00rootroot000000000000005435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G 5435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G bcftools-1.21/test/csq/ENST00000341065/not-a-start-lost.txt-l000066400000000000000000000002211467060157400227600ustar00rootroot000000000000005435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G 5435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G bcftools-1.21/test/csq/ENST00000341065/not-a-start-lost.vcf000066400000000000000000000005351467060157400224760ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 5435 . C G . . EXP=missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G;type=ENST00000341065:865694-C-G:incomplete cds bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor1.txt000066400000000000000000000024211467060157400236600ustar00rootroot0000000000000016255 CCC CC intron|SAMD11||protein_coding 16255 CCC CC intron|SAMD11||protein_coding 16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding 16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding 16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding 16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding 16438 GG G intron|SAMD11||protein_coding 16438 GG G intron|SAMD11||protein_coding 18365 A AA intron|SAMD11||protein_coding 18365 A AA intron|SAMD11||protein_coding 18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding 18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding 18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding 18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding 18506 G GA intron|SAMD11||protein_coding 18506 G GA intron|SAMD11||protein_coding 18816 CAGGTCT CAGGTCT . 18816 CAGGTCT CAGGTCT . 18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A 18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A 19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG 19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor1.txt-l000066400000000000000000000024211467060157400241110ustar00rootroot0000000000000016255 CCC CC intron|SAMD11||protein_coding 16255 CCC CC intron|SAMD11||protein_coding 16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding 16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding 16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding 16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding 16438 GG G intron|SAMD11||protein_coding 16438 GG G intron|SAMD11||protein_coding 18365 A AA intron|SAMD11||protein_coding 18365 A AA intron|SAMD11||protein_coding 18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding 18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding 18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding 18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding 18506 G GA intron|SAMD11||protein_coding 18506 G GA intron|SAMD11||protein_coding 18816 CAGGTCT CAGGTCT . 18816 CAGGTCT CAGGTCT . 18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A 18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A 19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG 19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor1.vcf000066400000000000000000000025221467060157400236210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 16255 . CCC CC . . EXP=intron|SAMD11||protein_coding;type=splice should not be called, can be normalized 1 16261 . CCA CA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice_region but not splice_acceptor 1 16429 . TA T . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice_region but not splice_donor 1 16438 . GG G . . EXP=intron|SAMD11||protein_coding;type=splice should not be called 1 18365 . A AA . . EXP=intron|SAMD11||protein_coding;type=same as 16255 but an insertion 1 18371 . C CA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=same as 16261 but an insertion 1 18500 . T TA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=same as 16429 but an insertion 1 18506 . G GA . . EXP=intron|SAMD11||protein_coding;type=same as 16438 but an insertion 1 18816 . CAGGTCT CAGGTCT . . EXP=.;type=ref not a variant 1 18826 . G A . . EXP=missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A 1 19026 . CAGGTGGCCAG CAGGTGAG . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG;type=indel inside exon not splice bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor2.txt000066400000000000000000000000771467060157400236660ustar00rootroot0000000000000016255 CCCCACCCAGA CCCACCCAGA . 16255 CCCCACCCAGA CCCACCCAGA . bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor2.txt-l000066400000000000000000000000771467060157400241170ustar00rootroot0000000000000016255 CCCCACCCAGA CCCACCCAGA . 16255 CCCCACCCAGA CCCACCCAGA . bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor2.vcf000066400000000000000000000004621467060157400236230ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 16255 . CCCCACCCAGA CCCACCCAGA . . EXP=.;type=should not be called, can be normalized bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor3.txt000066400000000000000000000002131467060157400236570ustar00rootroot0000000000000016261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding 16261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor3.txt-l000066400000000000000000000002131467060157400241100ustar00rootroot0000000000000016261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding 16261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor3.vcf000066400000000000000000000005671467060157400236320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 16261 . CCAGA CAGA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=CCAG[A>C-AGA[A, splice_region but not splice_acceptor,non-synon region bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor4.txt000066400000000000000000000002071467060157400236630ustar00rootroot0000000000000016427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding 16427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor4.txt-l000066400000000000000000000002071467060157400241140ustar00rootroot0000000000000016427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding 16427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor4.vcf000066400000000000000000000005211467060157400236210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 16427 . GGTA GGT . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice_region but not splice_donor bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor5.txt000066400000000000000000000002651467060157400236700ustar00rootroot0000000000000016427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding 16427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor5.txt-l000066400000000000000000000002651467060157400241210ustar00rootroot0000000000000016427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding 16427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor5.vcf000066400000000000000000000005321467060157400236240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 16427 . GGTACTGGGG GGTACTGGG . . EXP=synonymous&splice_region|SAMD11|ENST00000341065|protein_coding;type=should not be called bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor6.txt000066400000000000000000000000771467060157400236720ustar00rootroot0000000000000018365 ACAACTCAGG AACAACTCAGG . 18365 ACAACTCAGG AACAACTCAGG . bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor6.txt-l000066400000000000000000000000771467060157400241230ustar00rootroot0000000000000018365 ACAACTCAGG AACAACTCAGG . 18365 ACAACTCAGG AACAACTCAGG . bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor6.vcf000066400000000000000000000004621467060157400236270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 18365 . ACAACTCAGG AACAACTCAGG . . EXP=.;type=should not be called, can be normalized bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor7.txt000066400000000000000000000002151467060157400236650ustar00rootroot0000000000000018371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding 18371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor7.txt-l000066400000000000000000000002151467060157400241160ustar00rootroot0000000000000018371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding 18371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor7.vcf000066400000000000000000000005201467060157400236230ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 18371 . CAGG CAAAGG . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=same as 16261 but an insertion bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor8.txt000066400000000000000000000002071467060157400236670ustar00rootroot0000000000000018498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding 18498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor8.txt-l000066400000000000000000000002071467060157400241200ustar00rootroot0000000000000018498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding 18498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor8.vcf000066400000000000000000000005121467060157400236250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 18498 . GGT GGTA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice region but not donor bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor9.txt000066400000000000000000000000731467060157400236710ustar00rootroot0000000000000018498 GGTAAGGGG GGTAAGGGGA . 18498 GGTAAGGGG GGTAAGGGGA . bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor9.txt-l000066400000000000000000000000731467060157400241220ustar00rootroot0000000000000018498 GGTAAGGGG GGTAAGGGGA . 18498 GGTAAGGGG GGTAAGGGGA . bcftools-1.21/test/csq/ENST00000341065/splice-acceptor-donor9.vcf000066400000000000000000000004271467060157400236330ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 18498 . GGTAAGGGG GGTAAGGGGA . . EXP=.;type=no consequence bcftools-1.21/test/csq/ENST00000357367/000077500000000000000000000000001467060157400166575ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000357367/ENST00000357367.fa000066400000000000000000000102351467060157400210200ustar00rootroot00000000000000>1 1:13386626-13390785 TTACGGAGGACACCAGATAGTTTCCACTCAGTTTCCCTTTATTTCTGACTGTTACTTTAC AACCATCTGTGCAGGGGTAACCCTCTCATGTGTCTCTCCTCCCTGATTCTCACTCTAGCA ATTCAGATTCCCATTTCTGATTCTCTGGGACACAGGTCTCTAAAGAGCCCATCCACTCCA AGTCAACTTTTCCCCCAGTCCTGCCCCTCCTGCATCCTCATTCCTTTCCCATTCACACTG AGGAGGCATTTGAAACGATGGGTCTGTGCTCCCTTTAACATGCACTCATGGCCTAGGTTT CAGCTCCGAAATGACCAGAAGAAAGCTTGAAATATATCCACCCTGATGGCAGGCATTCAA CAGAGGCAGTGACTGGGCTCCAGGTCATAGGAGGCCCTGATGCCACAGCGAGGGCAGGGG ACGGTGCAGAACACAATGATCTTGGGCTGCCTTAAGTCCCTCAGTGTCTTCATCAGCTCA GCCCCAAGTTCAGCAAATCTCCCCCAGCAGAGAGCACCCTGGGTGTCATAACTCTCCAGA GGGGCAGGATACAGCTCCAGGCTTAGCTTGCTCAGCCCGACGGTGTGGCGCAGCAGGTTC TCAAGGGCAGCCATGGAGATGAGGTTCCCACAGAAGCTGAAGGTGCTGAGCTGGGAGCAG CGGCTCAGGACAGGCAGGATGGCGCTGAGTTGGGAATCCATGATCCCACAGTCCTCTAAG TCCAGGGTCTGCAGGGTGGCCACAACTTGCTCCAGCAGACCTGTGAGGGGCTCAGGGCTG AAATGGGTCAGTGTGACACCCCTCAGGTCCAGCTCCTTTAATTGACGGATGCTCGGGCAC CAAGAGAGATGCTTCAAGTCCGACTCTGACAGCAGGCAGTCGGTCATAACGACCATCTCC AAGGAGGCCTGGAGACACCTGGGAGAGAACAAGAAGTAGTTAGAGGAGAGAGGTGGGGAT GACTTCAGGGTGAGAGATGATGCTCTCCATAACCCAGGGCTGCTCTGCTCATCTGAGGAT AGTCAGCACCTGGGGTGTGGGAATGGAGACTCTGTTCCTTCAGTGCAGTCCCAATCGAGG CTCAGTCCTTCACCATCACCGAGGTGATTGGATCAAGTCCATGAACTCTAAGTCTCCCTT TCCTCATCTGTCAGGTAGAAAACCGCATCTCTGGGCCACAGGAGCCCGATGGAGACACAG GCATAAATGACAAACCCAGGCAGGATCCTGCAACATCAGCTGGGTTGGCCAGGTTGCAGG GGACCCTGACATGCCTGTACCATCAGCAAACCATCTATCACTTTTACCATTCTTTGCTCC TGCTCCCTCACCCTCTATTCTATCATCATGTATTTCCCATACATTAATTACCTGACCTGG AGCTCAAAACAGGGTGCTGACAGGGAAACATAGGATTTTGCCTGTTCACTAGGCAGGTGA GGATAGACCTCATATTTTAAAATATAGGAGTGGGATGGGCATTCTCTTTAGTGCCCTCTT CACCTCCCTATTTCCCATCATCTTAACTTAGACACACATCCTCAGGAGGAATTCACAAAT GCACTCTCGCCAGATCTAAACCCTGCAGTAGCTAGCTTCCTAGCTTGGCACCTTCTCTAT AGCATCTAGCCCAGGAGATCCCTCTGACTTTATTGGGATGGTTGTGTGATACCCGTATCA GGACAGAGCCACCAACAGGATAATGCATGGATATTCTAGTGTCCCCTCACTCTTACTTCC TCACAGGCTCACAGTGCATACCCACTGGTGTTTACTGTAACAAAGAAAGGCTCTGCTGTG GTCTGAAGAGAAAGCTCACCATCCTTCCTCACCTGAGCAGCTGGTCCAGGTGGCCTTCGA GGAAAGAGACGGAGTGCATAGACAGATTCTGGAAATAGTCCAGCTTGAGGAACTGAGAGG TGAATCGGGCAATGAACTGCCCCTTGTTGTCTGGGGGAATGCAGGCAGATGCACGGATGT TGAAGAGAACAAGTTTGCGGAGATTCCTCATCTGGCCCAGGTAAGGGGCAAACTTCACAA GAGTGGACAGCTCCCAGGGGCAGCACACTTCCACCTCCTGGATACAGTCAAGCTCCACCA TGTTCAGGACCTCTATGATACTGTGGATGGGCATTCCAAAAACCTGCAGCTCCTGGCAAC ACACATGCAGTAAGCCTTTTCTCTGCTTGCCCCACTCTAAGAGGTGGGTGAGGCATTCAT CTAGTGTCCTGTTCTTGAGACAAAGGTCTATGAACACCATGAATGGCTGCTGCCTGCCTG TCCCTGGACAGTTATCTGCTGTTTGCTTCTGACTCAGAGCCTCCGGGAAGGATGCAGTAG CTCCAGAAAATATGTCGCAGAAGTTCTCATCCACATTCCTCAAGTCCAGCACTTGAAGTT TTGACTGCCTGTGGGTAAAGGAGAAGAGAGGCTCCAAACTAAGGCAAGGACCTGAGCTTT TATTTACATCCCAGACATCAGCTGTTCTCCTCTCTGCCACTTTTCCCTCTCTGATTTTGT CCAACCCCTTTTCCCTCCGGATTTTGCCTCATCCCCATTGCCTGTAGCTTTCAGAGCCAC TAGAAGAGAAGTTTCTGTTTCCTCAGTGGACCCTGCATGGTGAGCAGTCCTTTCCCAGAG GGGCTGGGCAATGGCCAAGGCCTTCCTGAGCTTCCTCACTGGCACCATCAGAAACCTCTG GGCCTCCATGGTGCCCCTCCTCCTCCTGAAACAGCTGTCCCTACCCTGGACAAAAGGGCC CTCCCCACCTGGACACCTGGGTCACCTCACCTGGGGCGAACCTCTTGGGTCAACAGCACA TCAACCCCTTCCAGCACAGATTTTAATGACTCCAGATGAGGCGACTTCATCAGGGACCCT AGAGGGAGGCGGGTGAAAGGCCAGGCCTGCACCATTGTTTTCAGGGTTTCACAGCGTCTC CTGCTGAAGGCCTCCATGAACAGTGTGGGGAAGAGCTCCCTGGGCAGCTCCTCCATGGTG GAGATGGCCAAGGCCTGGTCCCTCAGCAGCCTCTGCCTTGCCAGCTCCAGGAGTCTGGGT GGGGCCCTGATGCTCATCTTGATGAATCTGCAAGGGAAAACTCTAGAGGACAAATCCAGA GAAAAGGCATCACTCTCAGGCCAAATATGATCACCTCATCTTCTCCTATTGCTAATCTCA TTGCTCTGGTGGAGGTGGAAAAGCCCTCAATTCCCCCCAGTTCCATTCTGCACTTGGTGG CCACAAATCTGTATCTGTGCCCCTGTGACTACCACAAAGAATGTCTTCCAAACACCAAGG AGGGGACGAGGTGGCCAGTGGCCCATTAATTTCTATACATTGCTCCACTGAAACTCAGGA TTACTGGGATCTGTCACTCAGGATCCTGAAAGCTAAGCTCCACCTTTTTGAGGGAAATTT TTTTGTTACTTACCACCCAAAAACAATGAGAATGACTGTCCTGTGGCCCCACACAGCCTG CATTCTCAGTTTACACAATTAGCATGCTTGGGGAAGACTGAAGTGACTCCTTAAAATCAA TGCCACTTGTTTTTATTTTGAAAAATTATAAGAGAAACTCTAAAAGCAGTGTGGCAGTAT TCTAGAGCACTTGGAAGGTGCGGGTGGAAACACTAAGTCTCAGATGAAGGATCCAATACT CATCCCTTCTACATACTCACAATCACCCACTTAGGGACAGAGTCTAAGGGCAGAGATAAA TCCCATGTTCAGAACAAGACTCGAGAAAATCACAATACAACTAAGTGTGTGAACTGTAGC TGAAGGGCACAGAAACAAAGAACTTCACATGTCAAGACATAAAAATTCATCCAACTGTAA ATTTTTAATATCTTTTTTAAAAAACTGCTTCAATAAGAATTTTGAAATGAGAAAAATGAA GCAGAAATCAAAATCTGAGGGATGAAGTGAATACTATATTTAGAGGAAAAATCAAAACCT ACATCTGTTAAATTGAAAAAACAGACAGGAAATTCTCTGTGCCACTTTGGGCTGTGTGTC ACCATCCCTGACTGGCTGGCTGCAGATCAGATGGGCGTGTTCCTAAGGAGGTGGTGACTT ACCAGATCTGGACTCAGTTTGTAGGGTGCTGGGATCTCTCAGAGAATCAAGCAGTAGTTC CAGGCACCAGGGCTTTGGGT bcftools-1.21/test/csq/ENST00000357367/ENST00000357367.fa.fai000066400000000000000000000000201467060157400215450ustar00rootroot000000000000001 4160 23 60 61 bcftools-1.21/test/csq/ENST00000357367/ENST00000357367.gff000066400000000000000000000034551467060157400212020ustar00rootroot000000000000001 ensembl_havana gene 21 4140 . - . ID=gene:ENSG00000182330;Name=PRAMEF8;biotype=protein_coding;description=PRAME family member 8 [Source:HGNC Symbol%3BAcc:24074];gene_id=ENSG00000182330;logic_name=ensembl_havana_gene;version=6 1 ensembl_havana transcript 21 4140 . - . ID=transcript:ENST00000357367;Parent=gene:ENSG00000182330;Name=PRAMEF8-001;biotype=protein_coding;ccdsid=CCDS30597.1;havana_transcript=OTTHUMT00000022043;havana_version=1;tag=basic;transcript_id=ENST00000357367;version=2 1 ensembl_havana three_prime_UTR 21 356 . - . Parent=transcript:ENST00000357367 1 ensembl_havana exon 21 918 . - . Parent=transcript:ENST00000357367;Name=ENSE00001763203;constitutive=1;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001763203;rank=4;version=1 1 ensembl_havana CDS 357 918 . - 1 ID=CDS:ENSP00000349931;Parent=transcript:ENST00000357367;protein_id=ENSP00000349931 1 ensembl_havana exon 1833 2408 . - . Parent=transcript:ENST00000357367;Name=ENSE00001787203;constitutive=1;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001787203;rank=3;version=1 1 ensembl_havana CDS 1833 2408 . - 1 ID=CDS:ENSP00000349931;Parent=transcript:ENST00000357367;protein_id=ENSP00000349931 1 ensembl_havana CDS 2791 3077 . - 0 ID=CDS:ENSP00000349931;Parent=transcript:ENST00000357367;protein_id=ENSP00000349931 1 ensembl_havana exon 2791 3102 . - . Parent=transcript:ENST00000357367;Name=ENSE00001764121;constitutive=1;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001764121;rank=2;version=1 1 ensembl_havana five_prime_UTR 3078 3102 . - . Parent=transcript:ENST00000357367 1 ensembl_havana exon 4083 4140 . - . Parent=transcript:ENST00000357367;Name=ENSE00001633251;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001633251;rank=1;version=1 1 ensembl_havana five_prime_UTR 4083 4140 . - . Parent=transcript:ENST00000357367 bcftools-1.21/test/csq/ENST00000357367/stop-retained.txt000066400000000000000000000002271467060157400221770ustar00rootroot00000000000000358 C T stop_retained|PRAMEF8|ENST00000357367|protein_coding|-|475*|358C>T 358 C T stop_retained|PRAMEF8|ENST00000357367|protein_coding|-|475*|358C>T bcftools-1.21/test/csq/ENST00000357367/stop-retained.vcf000066400000000000000000000006531467060157400221410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 358 . C T . . EXP=stop_retained|PRAMEF8|ENST00000357367|protein_coding|-|475*|358C>T;type=ENST00000357367:13386983-C-T bcftools-1.21/test/csq/ENST00000360372/000077500000000000000000000000001467060157400166455ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000360372/ENST00000360372.fa000066400000000000000000000343341467060157400210020ustar00rootroot00000000000000>chr1 chr1:201358989-201373274 GAAGGGGACGTGACAGAAATGCCAGTCAGTGTGTGGTGGCTTTTTATTACTGGTGTGGAG TGGGTGTGGGGGCAGGCAGGAGTGGTGGCTCCCACCTAGGCCAGCTCCCCATTTCCAAAC AGGAGCTGCCTGGGGTGCCCAGGAGGGCCCGGGAACTGGGGGAGTGCAGGCCGGAGGCAG GTGCGAGCGAGGAGCAGATCTTTGGTGAAGGAGGCCAGGCTCTATTTCCAGCGCCCGGTG ACTTTAGCCTTCCCGCGGGTCTTGGAGCTGCAGGGGAAGCAGGACGCAGTGACATGGAGA CACAGGCAGGGTAGTAGGTCACCATGCGGCTGGGGTAGGACTGGGGTGCCAAAGGGGAGA GGAGCAGGCTGGAGCTGCCTCCAGGGGCAGAATAGGACAGCAGCCTGAGGCTGGAGGGAA GCTTCTCCGCCCCACATTTCACCCCCACCAGCAAGCAGAGGCCACAGGGAGAGAAGCACG AGGCCCCGGAGGAGCCAGAGAAGGAAACCTGTGGGCTGAAGCAGAGGAGGAAGGGCTGGG AGCCTGGGGCCCTCCAAGGAGGAATGGGATAGCTGGAAGGTAGGGAAGGAGGGGGCAGGG GGAGGGCTAGGCGAGAATGACCTCAGACACTTACACTTTCTGGTTATCGTTGATCCTGTT TCGGAGAACATTGATCTGCAAGAAAAGTGGGAAGGACAAAGAGCAACGCTGGAGCTGACT GGCTCAGGTCCCAGGTGGCCTGGGGATGGGGAGAAGGGGGCTGAGTGCAGCAGTGCAGGA GGAGAAGGAGGAGCATGGAAGAGTAGGAGGGGTTAGGATAGTTAAGGGTCAGGAGGGGCC CGTGTACCACAGGCAGAAGCCAAGGAGAAGCTTCCAGGATGCCTCATGGGCCTCCCACTG TGGGGTCCCAGGGCCATAATAGGTTCAGGATATGAGAGTCCCATAAGAAGGGCCTCTGAG AGCTGGGCACAAAGCTGGAGGCTGTGTCATGGAGCCCTCCTAGCAGCCCAGCCCCAGACC CCTCTGGGGCACCCCTGCCCAGCTGCCCACCATCCCGGAAGCTGTGCCCTTTGAGCAGTA GCATCCCCATGCACCACCCCTGCAGGGTGCTGCCCCAAAGTTTGGCAAATCTGTGTCCTG TTGGCCGGTGCAGAGTTCAGTGTGGAACCAAAAAAAGAGAAAAAAGTGGAAGGCACAGGA CTAGAGAGGCCATAACAATGGCTGACACCTGCTGAGCATTTAGTGGGTGCCAGGCTCTGT CCTGAGCACCTTCCCAGATATGAACCCATAGGGCTGCTATGAGGGCATAGTAAGTTAATA CATGGGACATGCTTGGAACAGTGGTTGGAACACTATAGCAATAATAACAATTAGTATTAT CTCTGTAACCCTCACAATCACCCTCTGAAGTATATTGTAGTGTTACCTGTGGAAATGGAG GCAAGGAACAGTGGACTAACTCACCCAATGTCACACAGCCAGTGAGGGGCACAGGTAGAA ATTCAACCCAGGCATTATGGCTCCAAAGTCCATGCCACTGTCACCAGGCAATACAGCCTC TCTCCGTATTGGGAGGTGGGAGTACCCTGTAGCCACTGCAGCCTGAGCCTGCCCAGCGAG GGGCTTCTTGCCCAGGGAGGAGTGGTTTGGCAGGAGCAGCAAAGGAGACCTTCCAGGGGA AGCTGAATTCTTCCCTTAGGTAGCAAAGAGGCCCTGGGACCGGGGCTCGGGGGTGGTGGG TAAGGAAGGACTGGCGCCCAGGTCTAAGCTCCGGTATGCAGCATCAGTGTCCTCTAAGCC ATTTCCTTGCCTGGTGTCTGTTCACCTAAGACCCTCATTAGTGCACATAGGACTCCGAAA GACTGTGAGCTTGAGGCTCAGCCTAATTGTGCCCACACCAGGACCTTGGGTGTATGTGGG GAGAAGCACCTCTCTGTTGGCAGCACTCCCCTTCCACTGGGGGTCCTGGCTTGGTGCATC CTGGTCCTTGTAACCAGCTCAGATCACTGAGCTGCTGCCTCAACGTGTTGGAGACCCCCA GGGTTGGAACACCAGGAAAGTGTCTCTGCTCAGCCCCAGCGAGCTCTCAGACACTTCCAG CAAGCAGTCGTCAATGCGGTGGACATGGAACACTGCTGAAGGCCAGGCAGCAGGGGCAGA TGCAGGAGCTGAAGGGGGCTGTTGGGGAATAGGGACAGGGACCCAGGGACCTGCAGCAGT ATTACCGGACCCAGTGAACCAGGAGGAGTGTGAGATGGAGATGCTGGGCGGGGACAGCAT GGCGGCCCACCTCATATTTCTGCTGCTTGAACTTCTCCTGCAGGTCGAACTTCTCTGCCT CCAAGTTATAGATGCTCTGCCACAGCTCCTTGGCCTTCTCCCTGCACGGGCAAGGGTGAG AATGGGGAGGTCCAGTAAGAAAGGGCCCTCCTGGGCCTCCGTCCTGGTCCCGGCCCAGCC CCCAGCATCCCAGCCCTCCTTCCCACCTCCAGGCCTGCCAAGGGTACCCCAGCCCACCCC CTGGGCCTGACCCAGCCTGGGGACCAGACGGCAGCACCCAGTGCTCAGGAACGGACACCA GGGACTGCCAGGGCAAAGTTCCAAGAACAAGCGGGGAGCAGGAGAAGCCCTTCTGGCGCA GGAGAGCATCTAGTTCAATCCCCTGTCCTGACACCCGTGTGCAGGTGGGTAGGTGAAGCT CAGAGGGGTGGGGCACCTGCTCAGTTCTCTTTCCCCATCAGCAAAGCCCAGAAAGGAGTT GGCCCGACCTGCTGGGGCCCAGCTCTGGTCCCACCAAACTTGCCATGGGAAAATATGTGA GGCAGTCCTGCCCTCTGGTGGCTCACAGCAAGAAGTGCCCTTGGCCCGACCCCTCCCAGA GCAGATGCGGGCAGTGCCCCAGGACCATTCCTCCCAGCCCCCACCTCAGCTGATCTTCAT TCAGGTGGTCAATGGCCAGCACCTTCCTCCTCTCAGCCAGAATCTTCTTCTTCTTTTCCC GCTCAGTCTGCCTCTTCCCACTTTTCCGCTCTGTCTGGAGGGTGTGGGAAGCAGAGTAAA CTGGCCAGATTGCCCCCTCCCTGTCCCCTAACCCTCCCCAAACCCCCTGGGGGTGGAGCA AGGCCTGCAGGAGGGCCAGGTTCTTATGCTCTTCTTCCTGCCACACCCCCCAACTACCAA CTACATGTATTCCCTAGGGAAACTGAGGTAGGGGCAAGAAGGATCACGTCAGTCTCTTCC TTCTTTGCCTAACTAATCTCTTTCACCTCTCACCAGCTTCCCCCCTCCCCAGCCAGCCCA ATCTCTTCACTCCTCCCCTCCAGCAAGGCGCCTTCCCCTCCCAGGGAGCTCTCCAAAACT ATGGGGAGGAAGAAGGCTTGAGGTTTTTGGTACCCACCTGGGCCTGCTAAACCGGGAAAC CATGAGAGAGAGGCCCATAGAAAAAGACCAAGACGGCAACAGAGACACAGAGAGAAGGCA GGAAGACAAAGGCAAGGAGAGACATGGAAGAGAAGATTCAGATACTCGCTGTAGTCAGCC GGGTTTACTAGGACGTGGGTCTGAGGGTTACAGCAGGGGCTGTTCGGTAGCATGAAGACT TTGATGCCAAAGTCTTGGCTGGTGTGGTCACCATGGGGGCAGAGGCAGGGGGTGGCCTAG TCCTGAGCTAGGGACTAAGCTGGAAATCTAAGAAAATGTTTTGATTCCTTCACTACCTAG AGAAAATCAATTTCACATATCCCTCCTCCCTCGAGAATGGAGGACCTAGGAGGAATGGGG CACAAAAGTTAGGGATCGAGAGTGAGTTTCCAGGAACAAACAACCTCACATCTGTGTGGC ACATAGACACTTTCCATGGTAGCTCATTTGAGCTTCTCAAAGCATCAAGGCAGGCAATAT GAGTGCCAGTTGAGGAAACCGAGGCTCAGAGGTTGCAAAAGGTCACACAACTGTATGTGG CAGAGCTGGGTCTCCAACTAGAGCTCTGACTCTAGGCACAAGGCTCTTCCAGCTGCACCC AGCCTCCTTGGGGGCTCCTGAGCACTGCTGGAGCCAGGCATGGGGGGCACCATTGGTGCC CCAGGCTCTGCCTGTAGCCCCCTACCCCAGCAAGCCCCTCCTAGTGCAAGCCGCGGTCAG GCTGAAAACCAGCTCAGGGCTGGGCATGAGGAGACCTCAGTCTTCCACCCACAGCAGCTG GGAATCTCTTCCTGGGACCTGACCTAAAGTCTACCTGCTGCAGTGGACACCTCATTCCTC AGGGCTATACTAGGATCTCCTGGCAACCCCTGCTGCTCCCTACCTACCTTCTGGATGTAA CCCCCAAAATGCATCATGTTGGACAAAGCCTTCTTCTTCCGGGCCTCATCCTCAGCCTTC CTCCTGTTCTCCTCCTCCTCTCGTCGAGCCCTCTCTTCCTGATTTACAGCAGGGAGGAAG AAAGCAAATTAGGGGAAAGGATTGGAAACCCTGATTCTGGGCTGAAGCTTGTGGTCTTTA TGGGTGAGTTCAGCTTTCTCTCCGCTCAGCAAGGAGCTTTCTGAGAGGGTAGCTCCCAGC ACAGTGCTGGCCCACAGGAGTCCACTGACTGAGAAATGACTGCGTGATTGAATGAGGTCC TGATTCCCAAATGTGAGGTCTCGTCATCCCCTTAAGCTGGGAGTGCCCCTGGAAGACCTG TTGCTCTGGAAATGCCTTCAGCAGCTGCACAGGAAGAGAGCTACGGGGCCTTCGGTTCCC ACGAAGTCTGCACTGGGGAAGGGATGAGGGCTGGAGAGTCTTATAAAATAACACGTTCAT AAGGACGCAGGCATTTCTGTCTTGTTTGCTGATGTATTATCAGAGCCAAGACAATGCCCA GCACTTCCTAGGTTGATATTGATATTGTCTCTTTTTTTTCCTTTTTTTTTTTTTTTGAGT TGGAGTTTCACTCTTGTTGCCCAGGCTAGAGTGCAATGGCATGACCTCGGCTCACTGCAA CCTTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTAGGATGACC GGCATGTGCCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGACAGGGTTTCTCCGTT GGTCAGGATGGTCTCGAACTCCCAACCTCAAGTGATCTACCCGCCTTGGCCTCCCAAAGT GCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCAATATTGTCTCTTGACTGATTTCAT TCATGTTGATGAATAGAGAGGGGCCTGGGGGCCCAGCAGGAGCTGGGAGCATGGGGGGCC TCCATGGGCCTGGGCTAGGGGTCACTCACAGCCAGGCGGTTCTGCCGCTCCTTCTCCCGC TCATTCCGGATGCGCTGCTGCTCGGCCCGCTCTGCCCGACGTCTCTCCTAAGGAGAAGAG GCAAAGCCCACCCAGGTGTGCATAGGGAGAAGGTGACATCGCAGGTACAGAAACCTGCAT GGGGTGGCAAGGGAATTCCTGGGGGAGGGTTCCTTCCAGAGTCTTGAAGCAATGGTGCCC GGCCTCCAAGGGCCTCCACTTTCAACCAGCTCCACGGACGTGCACACCAGGGTACCTGCA GTGACCCACCTCCAACATTCCTCATGGTGAGACTGCCCTCCACAACTGGGAGACATCAGG CAGGCTCCTTCTGGGCTCTGCCCCCACCTCCATCCCACCCTGCCCTGGCAGCTGCTCTGT GCCATATGCTTGGATAGATGGCCAAGTCATTGCTCCAGCCAGAGCAGCATGTCTGTGGGA AGGCAAGTTTGATGGGGAGAAACAAAAGCAATCAAAGCAGCCTCCACGCTCTGCAGGAGA AGGATGTGGGATTCTGCAGGTCACACTCCCCTTCATCTGCGGGGGAAGAGGAGGCAAGGG CAGGGGTGGCGCAGCAGGCCTGTGACCAATCAGTCCACAGCCCGGGCCTGAATTAGGCCC TGGGGGAGGCCTGAAACAGATCAGACTCAGCTCTGGCAGTCAAGGAGCATCCAGTAGGAT GGGGAGGGAAGGCAGGGACCCGAGAAACCAGTCAGGGCTGCAGGAGCTGTGCAGAATGCT GGAGGGCCTCTGAAGGAGACCTCACACCTAGCTGGGTTTGAGGCGCCGAGGAAGGCTGTC TGGAGGAGGTGGGGCCTCACAAAAGGGATGGAGGACAGACTGGGCCATCAGAGAATGTTA GGTGGGCAGACTGGACACCTACGATCCTGTCTTTGAGAGAAACGAGCTCCTCCTCCTCTT TCTTCCTGTTCTCAAAGTGAGCCTCGATCAGCGCCTGCAACTCATTCAGGTCCTTCTCCA TGCGCTTCCGGTGGATGTCCTGTGGGTGGACCGCTGCGGCTCAGAGGCTGCCACTCCAAA GAGTCCAGAGGAGAGATGGGTGGGCTAGACACCCCCCAACGCAGTGCAAAAGACCTCTGG CAGGGCCTGGCGCCTGGCCAGGGAAGGGGTAACTGTGGCCTGAACCCAGGACCACGCTCA TGGATGGGCACCCAGCCTGGCTGGTGCTGCACCCCATCCCACCTATGCTCTACCCCAGCC CAAGGTCACAAAATCTCTGTCACTGAGGGCCCTTGGGACTATCCCCAGCCCAGGCCTACT CAACCCACAGCCACCGCTTACATCAAAGTCCACTCTCTCTCCATCGGGGATCTTGGGAGG CACCAAGTTGGGCATGAACGACCTGTTGGAGAGAGGAATAGTCAGCATCAGCCCCATTCT GGACCCAGGGACTGAGGGTGTCCAGGACAGGCAGGGCCCTGATCCTTCCTAGAGAATCTT CCAGCACTGCCCCGACCAACCACAGCAATGATAGTAACACTGACGTCAACAATGGCAGTC CTCAGCCTTGCTCAGCACCTGGGAATACACAAAGCTCTTTCACATATGCTATTTCACTTC ATGCTCATGATATGCCCATGAAGTGGGTACCGTTAATCTCACTTAGGAGAACTGAGGCTC AGGGAGGTAGAATGACTTGCTCAAAGCCACACAACTTGGAATCAAAGAAGCTGTGACAAG ATGCCATGCTTCTTGGACTTCAAATCCCCTGGTGGACCCCGCAGAAACTGGCCATGAACC TGGGAGTCTTGCAGTTTGGTCCTGGTCCCAACACATACTGAGACCCAGGGGGTTCTCTGA TTCTTCATGTCCCCATCTGCCCTCAGGTGTGTGGAGCTGAAATGAGATACCGCAGTGCAC AAGAGGCCAGGAAGGGGGAAGGCACTGGGCAAATAAATGGATCTGGGATGTCTTGGGCTG GTTTCAGAAGGCCCCACTGAAATGGGAAGAGCCTGTGAGTGGGCAGAGGTGCCATGGGTC AACCTCTGCTGGCAGGGTTGGCATCATAAAAAGGGAAATGCTCCCTATCCCCCAGCCCCC CCCAGCACACACCACCTTCAGGTGGGCTTCACGTGTGTGGCACCAAGCCGTCCTGCCCTC TCTCAGCTCTCTGAAGCCGCCATGCCTATGCTGGCACGGTTTCATTGTTTGGCTCCCCAC AATTTGCTTCCCTTAATCCCAAGGTCCCACCTCGGCCATGGAGGAGGGTGTTCTGGCCAT ACTGTGAGAGAGGAGAGTGTCCGTTCAGGGCCCTTCCTCTAGAAGAACATAGCCCCATCC CTGCTAGGGTGCACGATTGGTGATGGAGTGTTGGGTGGAATTCAGCCCTCACTCACTCCC TTAGGAAGAGACGCTTGTGCAGTACACAACTTGTACAACTGTACTGTGGTGCTCTGTGCC CACCAAACCCCCAGCCCGTGTCCACTGCACCATACTGCACCCCGTTCCATCATCATCCTC TCTCCCTGAGCCTCTGCTCCCGGCTCTACCCAGGTGCCTCCCCACTCACCTGGGCTTTGG TTTGGACTCCTCCATTGGGCCATCTGGAGGAGATAGAAGCACACAGCCATGGGTCAGGGG GCCCCAGAAGTGGTCCCAACTCCGCCCTCGATGAGCTAGATCCCTGTGGATTTCCATTTC CCCATCTGCACAGTGAGTCCCTCCCGGCACTGGGGAGCCCTGATTCCAGAAGCATCCAGG AGAATGAAGGCAGCGGGGGCTGCAGATGCCACACTCCCCCTCCCATAGAGTTCTGCAGGG CACACACTCACGCAGTGTGGAACTTCACACAAAGCCTTCTCTCACTCACCAGTTCTGGGC AAAGCAATTTTGCTTCTCTTGTGCTTCACAGTGACAAGGCCTTTGGAAAGGTCCCCAAGG GTCCTGGCCCTAGAATCCCCTCCCAGGTCTTTGCCTTCTTTGTTACCCCTTGGACTTCCC GGTGGCCACAGGGCAGAAGCTGATGACATGATTCCAAGCCCCAGCTGGTTGTCCCCTCCC CTTTGGAGAAGTGACTGGGACCACTTAGAACCCTGGTGAAGGCTGCAGCATGACGATGAC TGCAGCAATGACCCACCATGACCATCTATGCATTGGGATTTCATCCTACGGACACCACAT CCTACAAGTGATTTCACCTAAGCTCTAGGAGCTTCATGTGTGGATATGACTTCTGGGTCC CATTGCTCTGTCCAGACCAGGGGGCTGGACAATGGTCCCCTCTCCCACTGGGTGCCACCA ATGCAACTTCTCTGGGAGAAGGGGCAAAGTTGAAAGCTCAACATCTAAAACTTTGGAAGT GCCACCAAGTTCTGTCCTCTCCTCTCCCAAACCCTCTCAGTGCACATCCACTTCCCTGGA AAGAGCACTGTGGGCATTCTCCTCCAAAGCTGCTGTGAGGGGTTCCTTTGCCTCCCTTGT ACCTCTCTCCTGATATCCTTACCTTCAGCCTCCTTTGCTTCCTCTTCTTCTTCATCTTCT AAATGAAACACGAGAAATCAATCAAGGTCCTTGTTCTGAGCTCAAGTCCCCCCCTCCGCC ACCAGCAAGAGCCTTCCCCACAGATAAGCCCTAGCCAAGATGCACTCTGTTGGTTTTTGG GGTTACAGAGCTGTCTCTCACACACACATTCCCCTGGACCCAAGACTGCCTGACACAAGA GAAGCGCTGGGTCAACGTTTGTTGATTGGGCAATCAATGGTTGAATCTTAGTCAATAGGA GAGTCAGGTGCACATGGGAAAGCCTGTTCTGGGGGGTTTCTTACTGCCTCAGGAATGGCT CCAGGGGCTCTCGCCACCCCCTGAGGCCCCTGCACCCTCAACCAGAGACTTACCTTCTGC CCTGGTCTCCTCGGTCTCAGCCTCTGCTTCAGCATCCTCTTCCGCTGCCTCCTCCTGCTC TGGAGAAGTGAAGCAGACAGAGTGAAGAAGCAGGCCCCACTCATGCTATCAGGCAGAACC CAGAGCAGAGAATGGGCAGCGGGGAGTGGGGATGGGGGTCAAGACGTCTAGGTCCAGATG AATTTGGGGGCAACCAACGTGCTGGGGGGCTGCCATTCTTGGTTTTGACTGTCGGCTACC TCCCGCCACCCAGCTTAGCCCCACTCATCCCGGCAACCTCCCTGATGATGGGACTCCACC TCATTCCCCAACTTTCCAGCCCAGAAGTTCCACCCCGTGTCTGGCACCACAGAACATGCT CTGCTTAAGCCGAGGTGTCCAGAAGCTCCTGTCCTGAACCTAGTGACTCTAGACACCCTC AATCCACATCTCAAAGAAACCAAAAGAGTACGACTGTGTGGCTGGATGGCACACTCAATA TCTGGATCTTCGTACTATCCAGAAAGTGGGCAGGATTTTTCTATTTTCATCTATTTGTTT GGCAGGATGTGGCCCCCATCTCACTCAGGCACTTGGTGTAGACAGACAGACAAACAGATA AGGGAGACAGGATGCCGCCTGGCCTGGGCTGTGCCTGTAGGAAGTGTTCTGTGATGCCTG TTCACTGATGCACTGGGAAGTGGGTGCCTCTTGGCAGAGGGAGAAGAAAAACCTCAGACA GGAGGAAGACACCATCGTGGGAGAAGGGTTGGCCTTCATTCCCTCTGTCCTCCCTTCCCA GGTCTGAGTCCTCTCTGAAGCCTGGAGATGCCTTTTATTTGATCCCTGCAGGAGTCTTAC CTCAAAATGATCCTTCTAGAAAGTGTGAAAGCAGAGGGCTAGCGAGGAAGGACATGGCCA TTGTGGGGTCTACCTTTAGGCCATCTTGTTCACACCTCTGCCACCTCATCTGACGTGTCA TTTCTCTATATAATATACCCCAGCCCACCCAGTGGCCATGCAACATCCCAAGGATGGGGA GCTTACTGCCTCCCCAACCCACCTACTGCATCTTGAGATATAGCTGTCAGAACGCACTTT CTAAAATTAAGCCCTGGTCTCACTCCCTTGCCTTGGTCCTGTGCTCCCCATCAGCAGGGC GCATCTGAAGGCTGACGTCATGTCCTTCCTGCTCTGGCTATTTCCAGTCTCCCTGGCTGC TCTCCAGAGGACTCTGTCCCCAGACCCCCCAACCAACACCTGGCCACCCTGCTTGGTGCT GTCCAGCTCCTAAGGAGGGCCCAGCATGGAACACTGGGGTGTGCGCGGGGGCAGGGTGGC GCTGCTGTCTTCCAGGTGCCAGGTCCCCTCTATGGCCACATTTGGAGCAGCTTGGGAGAC CAGCTAGCCTTGGTCCCTCCCACCACCCAACCCAGGGGAAGGATCCAGGAACCAGGAAGA GGAGCCAGTGGCCCTGAAGTTCAGGCATGATGATCAGCTTGGAACTGTGATCCTGGCCCC TGGGAGGCAGGGGAGGAAACGACTGACCCACTCCGTCCCTGCCGCCTACTCACACCCCCC AGCCCCCAGAACAGGGCCCCTGGACAAGGAGGCTGCACTTGGGACAGCAGGCAGCAGAAA GCACCACAGAAGGAAAGGCTGTACTACCGTCTTCGTCCTCTCTCCAGTCCTCCTCTTCTG AGGTTCAGGGAGTGGCCGCAGCGGAGGGGAAAAGCGAGACAGGTTAGTCTGGGAGCAGAG AGCCCGCGGCAGGAGCAGCCACCCAGCGCAGTGGTTTTAAGAGTGTGGGCTTTGGAGTTA GGCCGGCATTCCAATTCCCAAGCCACTACTTTCCAGCAACAGGGGCAACTCTCAGTTACT TCCCTGAGCCTCAGGTGCCTCATCAGTAAAATGGGAATCATTCTACTCACTTCTCAGCCG TGGTGAGGACTGAATGACCTAGCGTGCATAGAGCGCCCAGCAGGTGCCTGGCACAAGAGG AGCATGCGATCTGTGGTAACTGCAATGCCTCTAGACGACAGAGCCTTGGCCTCCTTCTTA CTAAGACAGAGGCCCCTAAAGAGCAGAGAGTGGGGGACAATTCTCTTCCATCAAATTTCC TGCCCTCAACGAGCCTGCCCATGTTCCTGCTCTGAATGAGGCTCTTGGGTATCCTGCAAA CTATGTCCAGTTTCCAGGAGTCACACTTTAGAAAGCCTCATTGGAGAGCCTGGCCCCAGG GGAGATTTGCCCGGCCTGTTGGGAGGATGCTGCCCCATCTAAGAAGGGTCCAGCATTATA AATCTAAGGAAAGAGGCTGCATCTACAACAGTTGTTCTACGTACAAATATCTGCCCAAAA AAACAGTTCCAGCAAGTGGAACAATTCCTCTCCTGGAAGAAGGACACCTGGCATTATCTA TCCTGCAGGCTTAGTGGACACCCATCTAGACGTTGCTCTCTCTTGATCATTTGCAGCCAG ATCCTCAACTGTGTGGGAGGCAAGTCTCGTCTATTCATGGCAAGCAAGGCAGATGCTACA CGGCTCAGGCCCCAGCACAGTGGAGAATGACTCTGCTAACTCACAGCCAAATTCTACTGT GTGTGGCAGGCAGATTGGTCCCAAATCCAGAGATCTATGTCTCAAACTCCACCACCCTAA ACCTGTTATAAGGAAGTGGAAAATCCTCCAAAACAAAGGAAGGGATATCATATCAAGAGT CTGTTCAGGGAACACAGCAGAATTTGGAGCCAGTTAGATTTTTTATTCAAAAATATATTT CTGATAGCTTCTGAAGTATCTGGTGTTCCTTAAAAACCAAAAAAGACGCCTGTGGCCTCT TTCAGTTTCTCCTGTGAATTTCTCTTCTGTCTCCTCTTTGGCCAGACAGCCCTGGAACAG CCCTAAATGTGCAGGAGGGTCCCCATTTTCCCTAGGAGCCATGGGGAGCAAGGGCGGGGC CACCTGGGCTCCCCCCTTGGACCTTCATAGAGACCCTTCTCCTAATATCTACATGCCACA TGCTGAAGTGATACCTGAGCCACTAAAAGGCAGGGTCCACCTGCCTGGGGTGCAGGGGGA GGACTGGAGTGAAGCCTCTGAGTCATTTCCATGTGCCAAGCTCTCAGGAAGAAGGGAAGG TGAGGGCGTTCTTTCAGGGAGATGTGGGACCCACAGCTGAGGAGGGCGATGGGTTAACCG ATCAGCATAGGAGCAGCAAGAGGGGCCTCTGCAAGCTCAGAATCATGACAAATCTTCATG CCGAGATAAGACGTCTCAGATCACTGAGCAATTTCATACTCACAATCGCATTTGAGAAAT TACTAAATGGAATCTTTTGGGGCATATCATGGCATTGTGGTTATGGTTTTTAAGTAGTGC TTATCTCTTAGAGATACGGTGTAGCGAAATCTTGAAGCGTGAACTGACATGGTGCCTGGG AACAATTTTGGATGTCTGCTCCAAAATAACTGGTGGAAGGTGGAGTATAGAGGAAAGAAG ACTGGCCCTAAGATGATGATTGTTGAAGCTGGTAATGGGTACCTTGGGCAGGGGGGGCCA TTATTATTATTATTGCTACCTTTATGTGCATTTAAAATTTCCCATGATAAAAGGGAGAAG AAGCAAAAAAAATTGGGAAAAGTGATCAGTGTGTTTGAAGCAAATGGCAGACAGAAGAGA CAGGTTTAAATCGTTTGCCTCAAGACCCGAGCAACCCAGGTAGGACTGATTCCCATTTTA GAAGGCACTGTTGTTGGAGGATCTTGCTCAGCTGAGAGTGAGGAGCAGGGACAGATGAGC TGCTTTCCCAGGGCTCCCAGGATTTCCACATTGCTGAGCCTGCCCCTTTCTGGCTCTCCA CCTGCCTGAGGCACATACCTTCAACAGCTGCTTCTGCTCAGAAGAGAAGTCCAGGCAGCA AGAGAAGAGAGAAGAGGTGGGTCAGTTTCGAACCAGGCTGTCTTTGATCCAAATGAGTAC ACACGTTTACGCTTACCTTCCTGCTCCCTGAGAGCAACAGGAAACACTGTCAGTAGCTCG CACACAAGCACATGCAAACACACACGCCTGCACACACATGCACACACTGGCCTTTCCCCA AAGATAATCCCCCTTTCTTTTCCCTTGTTGCCTAGTGGAGTCCACGCTGCCCTGCCCACC TTGCAATGACACCCACTAGCCTGGCCTGCCGTTCTCATGCAGGGCTGCCTCCTACCATCC TCCGCAAGCCTCCGCCCCAGCCAGCTTGGTCTCACCAGCGTTCTGCTCACTTACTCTTTC CATCTTTGCCCAAGCTGTACCCCTTTCTAGAAAGTCCTGCCCTCTCCCAAATCTCTTATC TTTCCAAATTCTACACAGGTAAGACCTGCCTTCTCCACACAGCCCCCTGACTATTCCAGC CCCTGATCTCCCTCTCCTCAGAACTCCTACACTACCAACAGCCCGCCCTCCACACCAGGC CCCCAGTTGCTAATTTCTTCTCCCAGTTTATGTCTTAACATCTCAACAAGAGTAAGTTCT GTGAGGGCAGTAGCCGTGCCTATACCTCTGTCTCCTCCCTGGTGACCACTATCCTCTGTA GTTATTGGATTGGCTGTGTCCCACCCCCTGGTTTCCCTCTGGGATAGGACTGTGGGCAGG GCACTGTCATGAGAGAGTAGGGATCCAAGACAGGGTGATAACACTGGGTTCTGAGCTGGG GTTTGGGGGGCATAATCAGCTCTGTGCCTCTGGAGAGTCACTGAACCTTCCTCAGTCAGT TTCAGGAGACCCAACATCTCAGCTTCTCTGTTCATGGCCCCTAGCCAAGACTGGCCAAGG ACACTGATGACCCTGGAGCTGAACCTCTGTGCTTCCCGAAGTCTCTCGGCCTGTGCTCTG CCTGGGATCTACAACCCAGGGGTACAGGAGTGGAAAGGAAATGGCTATATCTCTCCTCGG GGTGCCCAAAACACACACAGCTACTTCTACCCAGAATCCGAGGGACAGCTGGGAGGCTCC TGGACCAGGTGTCAGGGCAGCGGCGGGAGAGGACCCCACTCAGGCAAGATGCTCCAGATA CTCACTCCTCCTCGTACTCTTCCACCACCTCTTCTATGTCAGACATGGTCTCTGCTCTCC CTCCAA bcftools-1.21/test/csq/ENST00000360372/ENST00000360372.fa.fai000066400000000000000000000000241467060157400215250ustar00rootroot00000000000000chr1 14286 31 60 61 bcftools-1.21/test/csq/ENST00000360372/ENST00000360372.gff000066400000000000000000000110711467060157400211470ustar00rootroot00000000000000chr1 ensembl_havana gene 20 18776 . - . ID=gene:ENSG00000118194;Name=TNNT2;biotype=protein_coding;description=troponin T2%2C cardiac type [Source:HGNC Symbol%3BAcc:HGNC:11949];gene_id=ENSG00000118194;logic_name=ensembl_havana_gene_homo_sapiens;version=20 chr1 ensembl mRNA 21 14266 . - . ID=transcript:ENST00000360372;Parent=gene:ENSG00000118194;Name=TNNT2-202;biotype=protein_coding;ccdsid=CCDS60390.1;tag=basic;transcript_id=ENST00000360372;transcript_support_level=5;version=8 chr1 ensembl exon 21 267 . - . Parent=transcript:ENST00000360372;Name=ENSE00003722768;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00003722768;rank=14;version=1 chr1 ensembl CDS 222 267 . - 1 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 635 675 . - . Parent=transcript:ENST00000360372;Name=ENSE00003490622;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003490622;rank=13;version=1 chr1 ensembl CDS 635 675 . - 0 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 2291 2381 . - . Parent=transcript:ENST00000360372;Name=ENSE00003488921;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003488921;rank=12;version=1 chr1 ensembl CDS 2291 2381 . - 1 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 2925 3034 . - . Parent=transcript:ENST00000360372;Name=ENSE00003666033;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003666033;rank=11;version=1 chr1 ensembl CDS 2925 3034 . - 0 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 4308 4418 . - . Parent=transcript:ENST00000360372;Name=ENSE00003523427;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003523427;rank=10;version=1 chr1 ensembl CDS 4308 4418 . - 0 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 5310 5387 . - . Parent=transcript:ENST00000360372;Name=ENSE00003686160;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003686160;rank=9;version=1 chr1 ensembl CDS 5310 5387 . - 0 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 6622 6682 . - . Parent=transcript:ENST00000360372;Name=ENSE00003514510;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003514510;rank=8;version=1 chr1 ensembl CDS 6622 6682 . - 1 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 7850 7883 . - . Parent=transcript:ENST00000360372;Name=ENSE00003718704;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003718704;rank=7;version=1 chr1 ensembl CDS 7850 7883 . - 2 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 8783 8815 . - . Parent=transcript:ENST00000360372;Name=ENSE00003646496;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003646496;rank=6;version=1 chr1 ensembl CDS 8783 8815 . - 2 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 9174 9239 . - . Parent=transcript:ENST00000360372;Name=ENSE00003520322;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003520322;rank=5;version=1 chr1 ensembl CDS 9174 9239 . - 2 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 10828 10857 . - . Parent=transcript:ENST00000360372;Name=ENSE00001444197;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001444197;rank=4;version=1 chr1 ensembl CDS 10828 10857 . - 2 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 13039 13053 . - . Parent=transcript:ENST00000360372;Name=ENSE00003554410;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003554410;rank=3;version=1 chr1 ensembl CDS 13039 13053 . - 2 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 13157 13167 . - . Parent=transcript:ENST00000360372;Name=ENSE00003661906;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003661906;rank=2;version=1 chr1 ensembl CDS 13157 13167 . - 1 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 chr1 ensembl exon 14226 14266 . - . Parent=transcript:ENST00000360372;Name=ENSE00001315772;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001315772;rank=1;version=4 chr1 ensembl CDS 14226 14266 . - 0 ID=CDS:ENSP00000353535;Parent=transcript:ENST00000360372;protein_id=ENSP00000353535 bcftools-1.21/test/csq/ENST00000360372/mnp.txt000066400000000000000000000002511467060157400201760ustar00rootroot000000000000004391 CC AA stop_gained|TNNT2|ENST00000360372|protein_coding|-|132EE>132D*|4391CC>AA 4391 CC AA stop_gained|TNNT2|ENST00000360372|protein_coding|-|132EE>132D*|4391CC>AA bcftools-1.21/test/csq/ENST00000360372/mnp.vcf000066400000000000000000000006751467060157400201470ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 4391 . CC AA . . type=ENST00000360372:201363379-CC-AA;EXP=stop_gained|TNNT2|ENST00000360372|protein_coding|-|132EE>132D*|4391CC>AA bcftools-1.21/test/csq/ENST00000368801.2/000077500000000000000000000000001467060157400170125ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000368801.2/ENST00000368801.2.fa000066400000000000000000000301341467060157400213060ustar00rootroot00000000000000>1 1:152184538-152196689 TGAGAAAAGTCTTAGTATTTAATCAACATTTATTTATTGTCAATTTTAATACAATCCGGT TGTTTGAATCCAAAGACTTGAAACAAATGTGTTACAGTCAAATTAAGGAACTATGTAGCA GTGACAGATACTCTTCCTTTTCATCTGGGCATGGATGATATTTTTTCAGGTGGAAACGTT ATTGAACTACAGTAGTAGGTGGAAAGCATTGTATTTCCATGGAATAACTCCTCAATATAT TTCCCAATATTGAGCAGCCTCTTAGAAATAGGGAGCAAGATCTTTCTGCTGAAAACAAGC TAAAGCCCACATTTGAATGTTTTTTTTTTTCCTGAAATGATAAATCCCTATTCTTTATGA AATAATGCTCTTGCTCACTGGCTTGGGAAAAGACCCTGATGCTACTTTTTTATGCCACTA ATTAACTTACTGATTAAATATATACCCAAGAAAAAGGACTTGATGGTTTTGATAAGTAAA GACACTACCGCTGCTGCATCTTTGCTTTCAGAGCCTTCACCTTCTGCCACAATACCAAAA ATTGGGACACACCAAACTTGGGGCACACTAAAAATTAGGGTACACTAATTGCTGTAAAAC AAAGCTTTGTATCTAGGACTGGTAATGCATTTGTAATATTTTGCTTCTAAGAAATGTAAG GTTAGCTTTGGCACCATCTATAAATGAATGATGAGCTCTCAAAAAGACAACTCCAACTAA ACCCAAAGCTCTTTAAAAGCTTTTCATTATTCCTCAAAGTTTAACCCTCATTCTAACAAG TTATTCCACTCAGTATTTTCTAACAAAGTAGCACAAATGCCTAACAGTCTTTGGAAGGAA CCCCATAACAAGATATATGCTACAGTTTTAGGCTCTAAAGAAAGAGACAGAAATGCATTG ATTCACTTTTAGAACGAATTTCATGATGGATTGCTTGTCTTTCATGATGAATTCATAGAT GACTTTCCTATTTCTTAAATTGCTACTTGAGTAAATTGCATTTATGTTTATTATTCACTG ATAAAAGTAGCACCTCTGCTCTTGGACATATTCATAGGGTGAAGTGCTACTAGGAAAACT GAGAAAATATGAGCCAGAACTTCCCCCATCATGGTTACTTCCTCCTTTGCAATAAGAATA CCCATCTTGCCCTGAGCCACTTCCATGCTGACTATAACCAGAGGACTGTCCTGAGCCAGA CCCATGTTGGCCGTAGCTGGAAGACTGCCCTGAACCAGACCCGTGTCGGCCGTGGCTAAG AGACTGGCCAGATCCAGCCCCATGTCGGCCATAGCCAGAAGACTGACTGGAGCCAGAGCC ACGGTGGCCATAGCTGGAAGACTGGCCTGTGCTAGATCCCTCCTGGTCAAAGGTTGATGA CTGTCCTGATGTAGAACCATGCTGTCCTTGGCTACAGAAGTGCCCTGAGCCACTACCATG CTGACTGTAAGCAGAGGAATGTCCTGAGCCAGACTCATGTTGACCAAAGACAGAAGAGTG ACCCAAGCGAGACTCATATGGGCCACGGCTGGAAGAACGACCTGAGCCAGACCCATGTTG GCCGTGGCTGGAGGAGTGCCCCAAACCGGACCCATGTCGGCCGCGGCTAGGGGACTGGCC AGATCCAGACCCTTGTCGGCCGTGGCCCGAAGACTGACGGGAGCCAGACCCATGCTGACC ATAGTGGGAAGACGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGA TCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCCAGACCCATGCTGACTGTA ACTAGAGGACTGCCCTGAGCTAGACTCGTGGTGACCAAAGCCAGAAGACTCGCCTAAGCC AGACCCATGTTGGCCACTGCTGGAAGACCGACCGGAGCCAGACCCATGTCGGCCGTAGCT GGGAGACTGCCTTGACCCAGACCCACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGA GCCCTGTCGGCCATAGCCAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGA AGACTGACCTGAGCTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACC ATGTTGCCCATGGGTAGAGGAATGACCTGAGCTAGATCCATGTTGACCGTAGCCAGAGGA CTGTCCTGAGCGAGACTCTCGGTGACCTAAGCCAGAAGAGTGACCGGAGCCAGACTCATA TGGGCCACGGCTGGAAGACCACCCTGAGCCAGACCCATATGGGCTGTAGCTGGAAGACTG CCCAGAACCAGACCCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCC ATGTTGGCCGTGGCCCAAAGACTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGA TGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTG TTGTTCGTAGCTGGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGTAACCAGAGGACTG CCATGAGCTAGACTCGTGGTGACCAAATCCAGAAGACTGACCTGAGCCAGACCCATGTCG GCCACTGCTGGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC GGAACCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGAGCCCTGTTGGCC ATAGCTAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGT GCTAGATCCCTCCTGGTCAAAGGTTGATGACTGTCCTGATGTAGAACCATGCTGTCCTTG GCTACAGAAGTGCCCTGAGCCACTACCATGCTGACTGTAAGCAGAGGAATGTCCTGAGCC AGACTCATGTTGACCAAAGACAGAAGAGTGACCCGAGCGAGACTCATATGGGCCACGGCT GGAAGAACGACCTGAGCCAGACCCATGTTGGCCGTGGCTGGAGGAGTGCCCCGAACCGGA CCCATGTCGGCCGCGGCTAGGGGAATGGCCAGATCCAGACCCTTGTCGGCCGTGGCCCGA AGACTGACGGGAGCCAGACCCATGCTGACCATAGCGGGAAGACGAACCTGAGCTAGATCC GTGTCGTTCACCCCTAGATGACTGTCCTGATCTAGAGCCGTGTTGTCCGTAGCCAGAGGA GTGACCTGAGCCAGACCCATGCTGACTGTAACTAGAGGACTGCCCTGAGCTAGACTCGTG GTGACCAAAGCCAGAAGACTCGCCTAAGCCAGGCCCATGTTGGCCACTGCTGGAAGACCG ACCGGAGCCAGACCCATGTCGGCCATAGCTGGGAGACTGCCTTGACCCAGACCCACGCTG GCCGTGGCCTGGAGACTGGCCAGATCCAGAGCCCTGTCGGCCATAGCCAGAAGACTGACT TGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGAGCTAGCTCCATGTTGGCC ACAGCTCGATGACTGTCCTGATGCAGAACCATGTTGCCCATGGGTAGAGGAATGACCTGA GCTAGATCCATGTTGACCGTAGCCAGAGGACTGTCCTGAGCGAGACTCTCGGTGACCTAA GCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCTGGAAGACCACCCTGAGCC AGACCCATATGGGCCGTAGCTGGAAGACTGCCCAGAACCAGACCCATGTCGGCCACGGCT AGGGCTAGGAGACTGGCCAGATCCAGACCCATGTTGGCCGTGGCCCAAAGACTGACGGGA GCCAGACCCATGCTGACCATAGCTGGAAGATGAACCTGAGCTAGATCCGTGTTGTTCACC CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTTCGTAGCTGGAGGAGTGACCTGAGCC AGATCCATGCTGAGTGTAACCAGAGGACTGCCATGAGCTAGACTCATGGTGACCAAATCC AGAAGACTGACCTGAGCCAGACCCATGTCGGCCACTGCTGGAAGACCAACCGGAGCCAGA CCCATGTTGGCCGTAGCTGGAAGAGTGCCCGGAACCGGACCCATGTCGGCCGCGACTAGG AGACTGGCCAGATCCAGAGCCCTGTTGGCCATAGCTAGAAGACTGACTTGAGCCAGAGCC ATGCTGACCGTGGCTGGAAGACTGACCTGTGCTAGATCCCTCCTGGTCAAAGGTTGATGA CTGTCCTGATGTAGAACCATGCTGTCCTTGGCTACAGAAGTGCCCTGAGCCACTACCATG CTGACTGTAAGCAGAGGAATGTCCTGAGCCAGACTCATGTTGACCAAAGACAGAAGAGTG ACCCGAGCGAGACTCATATGGGCCACGGCTGGAAGAACGACCTGAGCCAGACCCATGTTG GCCGTGGCTGGAGGAGTGCCCCAAACCGGACCCATGTCGGCCGCGGCTAGGGGACTGGCC AGATCCAGACCCTTGTCGGCCGTGGCCCGAAGACTGACGGGAGCCAGACCCATGCTGACC ATAGCGGGAAGACGAACGTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGA TCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCCAGACCCATGCTGACTGTA ACTAGAGGACTGCCCTGAGCTAGACTCGTGGTGACCAAAGCCAGAAGACTCGCCTAAGCC AGACCCATGTTGGCCACTGCTGGAAGACCGACCGGAGCCAGACCCATGTCGGCCGTAGCT GGGAGACTGCCTTGACCCAGACCCACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGA GCCCTGTCGGCCATAGCCAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGA AGACTGACCTGAGCTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACC ATGTTGCCCATGGGTAGAGGAATGACCTGAGCTAGATCCATGTTGACCGTAGCCAGAGGA CTGTCCTGAGCGAGACTCTCGGTGACCTAAGCCAGAAGAGTGACTGGAGCCAGACTCATA TGGGCCACGGCTGGAAGACCACCCTGAGCCAGACCCATATGGGCTGTAGCTGGAAGACTG CCCAGAACCAGACCCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCC ATGTTGGCCGTGGCCCAAAGACTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGA TGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTG TTGTTCGTAGCTGGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGCAACCAGAGGACTG CCATGAGCTAGACTCGTGGTGACCAAATCCAGAAGACTGACCTGAGCCAGACCCATGTCG GCCACTGCTGGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC AGAACCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGCCCCATGTCGGCC ATAGCCAGAAGACTGACTGGAGCCAGAGCCACGGTGGCCATAGCTGGAAGACTGGCCTGT GCTAGATCCCTCCTGGTCAAAGGTTGATGACTGTCCTGATGTAGAACCATGCTGTCCTTG GCTACAGAAGTGCCCTGAGCCACTACCATGCTGACTGTAAGCAGAGGAATGTCCTGAGCC AGACTCATGTTGACCAAAGACAGAAGAGTGACCCGAGCGAGACTCATATGGGCCACGGCT GGAAGAACGACCTGAGCCAGACCCATGTTGGCCGTGGCTGGAGGAGTGCCCCAAACCGGA CCCATGTCGGCCGCGGCTAGGGGAATGGCCAGATCCAGACCCTTGTCGGCCGTGGCCCGA AGACTGACGGGAGCCAGACCCATGCTGACCATAGTGGGAAGACGAACCTGAGCTAGATCC GTGTCGTTCACCCCTAGATGACTGTCCTGATCTAGAGCCGTGTTGTCCGTAGCCAGAGGA GTGACCTGAGCCAGACCCATGCTGACTGTAACTAGAGGACTGCCCTGAGCTAGACTCGTG GTGACCAAAGCCAGAAGACTCGCCTAAGCCAGACCCATGTTGGCCACTGCTGGAAGACCG ACCGGAGCCAGACCCATGTCGGCCGTAGCTGGGAGACTGCCTTGACCCAGACCCACGCTG GCCGTGGCCTGGAGACTGGCCAGATCCAGAGCCCTGTCGGCCATAGCCAGAAGACTGACT TGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGAGCTAGCTCCATGTTGGCC ACAGCTCGATGACTGTCCTGATGTAGAACCGTGTTGCCCATGGGTAGAGGAATGACCTGA GCTAGATCCATGTTGACCGTAGCCAGAGGACTGTCCTGAGCGAGACTCTCGGTGACCTAA GCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCTTGAAGACCACCCTGAGCC AGACCTATATGGGCCATAGCTGGAAGACTGCCCGGAACCAGACCCATGTCGGCCACGGCT AGGGCTAGGAGACTGGCCAGATCCAGACCCATGTTGGCCGTGGCCCAAAGACTGACGGGA GCCAGACCCATGCTGACCATAGCTGGAAGACGAACCTGAGCTAGATCCATGTTGTTCGCT CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTTCGTAGCTGGAGGAGTGACCTGAGCC AGATCCATGCTGAGTGTAACCAGAGGACTGCCCTGAGCTAGACTTGTGACCAAAGCCAGA AGACTGGCCTGAGCCAGACCCATGTCGGCCACTGCTGGAAGACCGACCGGAGCCAGACCC ATGTCGGCCATAGCTGGGAGACTGCCCTGACCCAGACCCACGCTGGCCGTGGCCTGGAGA CTGGCCAGATCCAGAGCCATGTCGGCCGCGGCCCGAAGCGTGATGGGAGGCAGACTCATG CTGACCATAGCTGGAAGATTGACCTGAGCTAGAGTCATGTTGGCCGGAGCTTGATGACTG CCCTGACGTAGATCCATGTCGTCCCTGGCTAGAGAAGTGACCTGAGGCAGAACCATGCTG ACTATAGCCCTGTCCTGAGCCAGACTCGTGTTGCCCAAAACCAGAAGCCTGGCCTGAGCC AGACTCATAATGGCCACAGCTGGAAGAACAACTTGTGCCAGACCCGTGTTGGCCGTGGCT GGAGGAGTGCCCTGAACTGGACCCATGTCGGACACGGCTAGGAGAGTGGCCAGATCCAGA CCCTTGTCGGCCGTGGCCCGAAGATTGATGGGAGCCCGACCCATGCTGACCATAGCTGGA AGACAAACCTGAGCTAGATCCGTGTTGTTCACTCCTAGATGACTGTCCTGACCTAGAGCC GTGTTTTCTGTAGCCGGAGGAGTGACTTGAGCCAGATCCATGCTGACTGTAACCAGAGGA CTGCCCTGAGCCAGACTTGTGACCAAAGCCGGAAGACTGGCCTGAGACAGACCCATGTGG GCCATTGCTTGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC AAAATCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGAGCCCTGTTGGCC ATAGCGAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGA GGTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACCATGTTGCCCATG GGTAGAGGAATGACCCGAGCTAGATCCGTGTTGACCGTAGCCAGAGGACTGTCCTGAGCG AGACTCTTGGTGACCTAAGCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCT TGAAGACCTCCCTGAGCCATACCCATGTGGGCCATAGCTGGAAGACTGCCTGGAACCAGA CTCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCCATGTCGGCTGTG TCCCAAAGATTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGATGAACCTGCACT AGATCCTTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTCCGTGGCC GGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGTAACCAGAGGAATGCTCTGAGCTAGA CTCGTGGTGACCAAAGCCAGAAGAGTAGCCTGAACCAGACACATATGGGCCACTGCTGGA AGATCGACCAAAGCCAGTCCCATGTTGGCCGGAGCTGGGAGACTGCCCTGACCCAGACCC ACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGAGCTGTGTTGGCCGCGGCCTGAAGA GTGACGGGAGGCAGACTCATGCTGACCATAGCTGGAAGACTGACGTGAGCTGGAGCCATG TTGGCCAGAGCTTGATGCCTGCCCTGACGTAGATCCATGTTGTCCCTGGCTAGAGGAGTG ACCTGAGCCAGAACCATGCTTACTATAGCCAGAGGACTGTCCTGAGCCAGACTCATGTTG CCCAAAGCCAGAAGTCTGGCCTGAGCCAGACTCATAATGGCCACGGCTGTAAGAGTAACT TGAGCCAGACCCGTGTTGGCCGTGGCTGGAGGAGTGCCCCGAACCGGACCCATGTCGGAC GTGGCTAGGAGACTGGCGAGATCCAGACCCTTGTCGGCCGTGGCCCAAAGACTGACGGGA ACCAGACCCATGCTGACCATAGCTGGAAGACGAACCTGAGCTAGATCTGTGTCGTTCACC CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCC AGATCCATGCTGACTGTAACCAGAGGACTGCCCTGAGCTAGACTTGTGTTGACTAAAGCC AGAAGACTGGCCTGAGCCAGACCCATGTGTGTCATTGCTGGAAGACTGTCCGGAGCCAGA GCCGTGTTGGCCATAGTTGGGAGACTGCCCTGACCCAGACCCACATTGGCCGCGGCCTGA AGACTGATGGGAGTCGGAGTTTTGCTCACCATAGCTGGAAGACTGACCTGAGTAGGAGTT ATGTTGGCCAGAAAAGTCTCTTTGAAAACTCAGTCTTCTGGATATGGATTCAGTCCCAGG TTTAAGACTTCCTCTGACGTTTCTGGAATAGGAATCATTCTCTCCTGCACTCCAACTTGA ATGACTAAAAGAGGATTCTTGCCGTTTGTTCTCCTCTTTTTCAGTTTCTTCTTGTTCCTC TTGGTGCTGGTGAGTGTCATCTCTCAGCTTTGACCCTGAAACTTGGCAGTAATCTTTGCC AATGATTTTATTACGAGCCTGAACCAGCTTGAATATCATCAGAAGATACTCAGTAAAATC CACTTTCTTGTTATGGTCTCGATCCAGACTTTGCAAGATGATATCCACAGTATCTGGATC GTTTGGATTCTGTATAAGAGAAAGGTACAAAGAGTAGCTCTGTTAGTATGGACAATACAT CTGGCTAACGAACTGAAGGAAAGATGTGAAAATGTAAATGTTTGGGTTATTTATATGGAA CTCATTCACACAGTCCTTTAGGCTGCATTTCTGTATCCTGAGCAGAAAGAGAAAAAGGAA TATGGAATGAATAATGTGGTGGGAAACAGCTAGAATAGGATGCAACTGGAAGATGAAAGG AAACAAGAGGGCTGATTATTTTTGGTAAAGAATGGGTCAAATATGAATGATTAGCTAATT TATAAGTAATATGTTTTTATACCTACATTAATTATATCAACTTTATTTATCCAATTAAAT TAACTAGCTACTTAATTTACTCACTGAACAAAGATTTATTATTTTACTAGTTGCCTACCA TTATGTCATATGAGAGTATAAAGAAGTGAACAAGTTTGCTTCCTGAAAAAAAATGGAATT TAAAGTTTAGTTGGCCAGATATACAAACTTAAAATTATAATTTATTGTGGTAAGGTTTCT ACAAGAGTACATCAGAGAGGAAACATTGGGGGTCCTAGAAAGGTTAATGAGAGGAAATGA TGCCTTTTGAAGGATGGATTAGGATTAGCCAAATGAAGAAGTAGGAAGAGAAAGAGAAGG GGAAAAGATTGTTCTAGGCAGAGGGAATTATATGAACAAAGGGCTAGAGGTGAGAGAAGT TATGGAGCATTCAAGGAACTGAAGGAAATTCAGGATTGCTAGATTTAGAGTTTGAAGAGT CAAGAAATGTGGATAGAGAGACAAATAGGGACTAGATTATGACTTTTAAGTTATGTTAAG GAACTTTGTACTTCATTTTAAGAGCAATTGGGAACTATTGAAGGATTTTTAGCTGAGGAG TGAAATGATTATATTTGCATCCAATGCTGAGAGTAGAAGTAGTAGGTGGCCTGAACCAGA GGACTAATAATAGTGATGAAGAGAAATGGGTTGTTTTGAGAGATTATTGATGAGTTAGAT GGAGGTTAGAAGGTAGTGGTGTCTGCTGAGAGAGAGACAATAAAAAATGACACCAGGTTT TTGCTTTGGGCAAAAAGATGAAGGAAAAAGGTTAGTGGGGAAGATTATGAGATTCATAGC TGACACACTGAATATCTGACATCTGATATCTGAATATCATATCTGAAATCCACAGAAATC CAAATTTAAGGAATTGAAACTCAGGAGTCTGATATAAGGTCCCAAATATCTAAGCTATCA AATCTAGACCTGACAGTTTTAAGGTGGTGGACACATTCTTTTGTGATTCAGGAGTAAATG CCAATTTCCTGAACTCAGAAATCTACTTCACAGTTTTTCTGAGGACTGTCTGGGTTTGTA GGAATTAGTCACTTAGATAGGACATTATTTAACCTGTGGGTTTTGTTTGTTGTTTAGTAA GGTCACTTCCGTTAGTTATGCTATGGAAACCATCACGGATCTGCTTTTGACCTTATCTCA AACTTTTACCAAACCCTGTTCTCTCTCACCAAGTAAGGACAATCCTCTAGGATGTTTGAC ATATGTGACAAGAAGGTGGAAAGGGATAAAGAAGAAAATTCCTGCATAACTCCATCCTGG CGTGGAGTTCTTACCTTCAGAATTTGATGAAACTCATTTTCCAGAAGTTCTTTCAGCTCT GCCTTGTTCAACGTATCATACTCCCCATGCTGGGTGGCATATTGGTAGAAAACATCGATG ACAGTGATGACGCCTTGTAGGAGTTTAGGCATTTTTTTTTTTGCAAGTTTGAGTAACCTA AAGGGAGGAAAAAGAGAGACCAACCCCTTACTATTCTTATTTCTTGTTTAAACACATAAA TAGTTCTAATTATTTATAATAATTGTTCAGAATTAGTCAGTCATGATTAAATTCATTCTG TTGTAATCAAGAACCAATTCAGAGTTGAATGACTTGTTCAAGCCATGTAGCAAGAGAGTG ATGAAATTAGGAATATAATCCATAGGTCTTATTTCCATTCCTGAATGAATGTAGGAAAAA TGACTTTCTGTTTTTGGCTTCCTGCCATTACCAGGGATAATATTAGCTTTGTTCTGGAGC TGTAGAAGTCCTGAGTGTTCCACTTCATCTGCTTCCTCTTTCTAGGTTCGAAGCATACTG TGGGCATAGGTCCATCATCTACATGACATGCCTTACTCAACCTAAGGAGCATCAATGGCT GAACTGAACTCTCAAGACTTCTAGGTCAGAGAAAATAGACAATGTGAGCAAAGCCAACAA GCCTAGGTGATATGAAGCTAAGGGTAACTGCTATTAGATCCAGCTTCTGTTCTCATTCTC CAAGCAGGAAGTGACCCTCAGACCTTATTACACAATAGAGAGGAAAAGCTCAGTTGTAAA GAAGGCAACCTGCCTGTGGATAATTAGAACCCCATGATATCCATGTTATAAGGGAAGCGA CCTCAAAGAAAGGAGATAATATACATAGTCCTAGTCTTTGTTTCATTTTTCTTTTCAGTA AATTTAAACTTATACCAAAGTTCCCCAGAGTATACTAAAAAGAAGCCTTGTATCTAGTGC CTCTTTGCCTTAGAGCACATCCTGGACTTTCATAATTTATAGCCCTAAGTACCCTTGAGC GGAGTTGAACTGCTCACTTACCTAGCTCACCAGAGGAACAAGTAGGGTAGAGACAGAAAC AGCTTTCAGGGTGCTGCGAGTTGGGCAGAGTG bcftools-1.21/test/csq/ENST00000368801.2/ENST00000368801.2.fa.fai000066400000000000000000000000211467060157400220340ustar00rootroot000000000000001 12152 25 60 61 bcftools-1.21/test/csq/ENST00000368801.2/ENST00000368801.2.gff000066400000000000000000000022061467060157400214610ustar00rootroot000000000000001 ensembl_havana gene 21 12132 . - . ID=gene:ENSG00000197915;Name=HRNR;biotype=protein_coding;description=hornerin [Source:HGNC Symbol%3BAcc:20846];gene_id=ENSG00000197915;logic_name=ensembl_havana_gene;version=5 1 ensembl_havana transcript 21 12132 . - . ID=transcript:ENST00000368801;Parent=gene:ENSG00000197915;Name=HRNR-001;biotype=protein_coding;ccdsid=CCDS30859.1;havana_transcript=OTTHUMT00000034016;havana_version=1;tag=basic;transcript_id=ENST00000368801;version=2 1 ensembl_havana exon 21 9429 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447986;constitutive=1;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001447986;rank=3;version=2 1 ensembl_havana CDS 11055 11192 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 1 ensembl_havana exon 11055 11217 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447987;constitutive=1;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001447987;rank=2;version=1 1 ensembl_havana exon 12082 12132 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447988;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001447988;rank=1;version=2 bcftools-1.21/test/csq/ENST00000368801.2/ascii-art.txt000066400000000000000000000002511467060157400214250ustar00rootroot00000000000000 > 1:11181-11211 11191 eeeeeeeeeeee........... -L--K--P--M- GAGTTTAGGCATTTTTTTTTTTGCAAGTTTG GAGTTTAGGCA-TTTTTTTTTTGCAAGTTTG GAGTTTAGGCATTTTTTTTTT-GCAAGTTTG bcftools-1.21/test/csq/ENST00000368801.2/start-lost.txt000066400000000000000000000002011467060157400216600ustar00rootroot0000000000000011191 AT A start_retained|HRNR|ENST00000368801|protein_coding|- 11191 AT A start_retained|HRNR|ENST00000368801|protein_coding|- bcftools-1.21/test/csq/ENST00000368801.2/start-lost.vcf000066400000000000000000000006421467060157400216300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 11191 . AT A . . EXP=start_retained|HRNR|ENST00000368801|protein_coding|-;type=ENST00000368801:152195728-AT-A bcftools-1.21/test/csq/ENST00000368801/000077500000000000000000000000001467060157400166525ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000368801/ENST00000368801.fa000066400000000000000000000301341467060157400210060ustar00rootroot00000000000000>1 1:152184538-152196689 TGAGAAAAGTCTTAGTATTTAATCAACATTTATTTATTGTCAATTTTAATACAATCCGGT TGTTTGAATCCAAAGACTTGAAACAAATGTGTTACAGTCAAATTAAGGAACTATGTAGCA GTGACAGATACTCTTCCTTTTCATCTGGGCATGGATGATATTTTTTCAGGTGGAAACGTT ATTGAACTACAGTAGTAGGTGGAAAGCATTGTATTTCCATGGAATAACTCCTCAATATAT TTCCCAATATTGAGCAGCCTCTTAGAAATAGGGAGCAAGATCTTTCTGCTGAAAACAAGC TAAAGCCCACATTTGAATGTTTTTTTTTTTCCTGAAATGATAAATCCCTATTCTTTATGA AATAATGCTCTTGCTCACTGGCTTGGGAAAAGACCCTGATGCTACTTTTTTATGCCACTA ATTAACTTACTGATTAAATATATACCCAAGAAAAAGGACTTGATGGTTTTGATAAGTAAA GACACTACCGCTGCTGCATCTTTGCTTTCAGAGCCTTCACCTTCTGCCACAATACCAAAA ATTGGGACACACCAAACTTGGGGCACACTAAAAATTAGGGTACACTAATTGCTGTAAAAC AAAGCTTTGTATCTAGGACTGGTAATGCATTTGTAATATTTTGCTTCTAAGAAATGTAAG GTTAGCTTTGGCACCATCTATAAATGAATGATGAGCTCTCAAAAAGACAACTCCAACTAA ACCCAAAGCTCTTTAAAAGCTTTTCATTATTCCTCAAAGTTTAACCCTCATTCTAACAAG TTATTCCACTCAGTATTTTCTAACAAAGTAGCACAAATGCCTAACAGTCTTTGGAAGGAA CCCCATAACAAGATATATGCTACAGTTTTAGGCTCTAAAGAAAGAGACAGAAATGCATTG ATTCACTTTTAGAACGAATTTCATGATGGATTGCTTGTCTTTCATGATGAATTCATAGAT GACTTTCCTATTTCTTAAATTGCTACTTGAGTAAATTGCATTTATGTTTATTATTCACTG ATAAAAGTAGCACCTCTGCTCTTGGACATATTCATAGGGTGAAGTGCTACTAGGAAAACT GAGAAAATATGAGCCAGAACTTCCCCCATCATGGTTACTTCCTCCTTTGCAATAAGAATA CCCATCTTGCCCTGAGCCACTTCCATGCTGACTATAACCAGAGGACTGTCCTGAGCCAGA CCCATGTTGGCCGTAGCTGGAAGACTGCCCTGAACCAGACCCGTGTCGGCCGTGGCTAAG AGACTGGCCAGATCCAGCCCCATGTCGGCCATAGCCAGAAGACTGACTGGAGCCAGAGCC ACGGTGGCCATAGCTGGAAGACTGGCCTGTGCTAGATCCCTCCTGGTCAAAGGTTGATGA CTGTCCTGATGTAGAACCATGCTGTCCTTGGCTACAGAAGTGCCCTGAGCCACTACCATG CTGACTGTAAGCAGAGGAATGTCCTGAGCCAGACTCATGTTGACCAAAGACAGAAGAGTG ACCCAAGCGAGACTCATATGGGCCACGGCTGGAAGAACGACCTGAGCCAGACCCATGTTG GCCGTGGCTGGAGGAGTGCCCCAAACCGGACCCATGTCGGCCGCGGCTAGGGGACTGGCC AGATCCAGACCCTTGTCGGCCGTGGCCCGAAGACTGACGGGAGCCAGACCCATGCTGACC ATAGTGGGAAGACGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGA TCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCCAGACCCATGCTGACTGTA ACTAGAGGACTGCCCTGAGCTAGACTCGTGGTGACCAAAGCCAGAAGACTCGCCTAAGCC AGACCCATGTTGGCCACTGCTGGAAGACCGACCGGAGCCAGACCCATGTCGGCCGTAGCT GGGAGACTGCCTTGACCCAGACCCACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGA GCCCTGTCGGCCATAGCCAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGA AGACTGACCTGAGCTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACC ATGTTGCCCATGGGTAGAGGAATGACCTGAGCTAGATCCATGTTGACCGTAGCCAGAGGA CTGTCCTGAGCGAGACTCTCGGTGACCTAAGCCAGAAGAGTGACCGGAGCCAGACTCATA TGGGCCACGGCTGGAAGACCACCCTGAGCCAGACCCATATGGGCTGTAGCTGGAAGACTG CCCAGAACCAGACCCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCC ATGTTGGCCGTGGCCCAAAGACTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGA TGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTG TTGTTCGTAGCTGGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGTAACCAGAGGACTG CCATGAGCTAGACTCGTGGTGACCAAATCCAGAAGACTGACCTGAGCCAGACCCATGTCG GCCACTGCTGGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC GGAACCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGAGCCCTGTTGGCC ATAGCTAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGT GCTAGATCCCTCCTGGTCAAAGGTTGATGACTGTCCTGATGTAGAACCATGCTGTCCTTG GCTACAGAAGTGCCCTGAGCCACTACCATGCTGACTGTAAGCAGAGGAATGTCCTGAGCC AGACTCATGTTGACCAAAGACAGAAGAGTGACCCGAGCGAGACTCATATGGGCCACGGCT GGAAGAACGACCTGAGCCAGACCCATGTTGGCCGTGGCTGGAGGAGTGCCCCGAACCGGA CCCATGTCGGCCGCGGCTAGGGGAATGGCCAGATCCAGACCCTTGTCGGCCGTGGCCCGA AGACTGACGGGAGCCAGACCCATGCTGACCATAGCGGGAAGACGAACCTGAGCTAGATCC GTGTCGTTCACCCCTAGATGACTGTCCTGATCTAGAGCCGTGTTGTCCGTAGCCAGAGGA GTGACCTGAGCCAGACCCATGCTGACTGTAACTAGAGGACTGCCCTGAGCTAGACTCGTG GTGACCAAAGCCAGAAGACTCGCCTAAGCCAGGCCCATGTTGGCCACTGCTGGAAGACCG ACCGGAGCCAGACCCATGTCGGCCATAGCTGGGAGACTGCCTTGACCCAGACCCACGCTG GCCGTGGCCTGGAGACTGGCCAGATCCAGAGCCCTGTCGGCCATAGCCAGAAGACTGACT TGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGAGCTAGCTCCATGTTGGCC ACAGCTCGATGACTGTCCTGATGCAGAACCATGTTGCCCATGGGTAGAGGAATGACCTGA GCTAGATCCATGTTGACCGTAGCCAGAGGACTGTCCTGAGCGAGACTCTCGGTGACCTAA GCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCTGGAAGACCACCCTGAGCC AGACCCATATGGGCCGTAGCTGGAAGACTGCCCAGAACCAGACCCATGTCGGCCACGGCT AGGGCTAGGAGACTGGCCAGATCCAGACCCATGTTGGCCGTGGCCCAAAGACTGACGGGA GCCAGACCCATGCTGACCATAGCTGGAAGATGAACCTGAGCTAGATCCGTGTTGTTCACC CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTTCGTAGCTGGAGGAGTGACCTGAGCC AGATCCATGCTGAGTGTAACCAGAGGACTGCCATGAGCTAGACTCATGGTGACCAAATCC AGAAGACTGACCTGAGCCAGACCCATGTCGGCCACTGCTGGAAGACCAACCGGAGCCAGA CCCATGTTGGCCGTAGCTGGAAGAGTGCCCGGAACCGGACCCATGTCGGCCGCGACTAGG AGACTGGCCAGATCCAGAGCCCTGTTGGCCATAGCTAGAAGACTGACTTGAGCCAGAGCC ATGCTGACCGTGGCTGGAAGACTGACCTGTGCTAGATCCCTCCTGGTCAAAGGTTGATGA CTGTCCTGATGTAGAACCATGCTGTCCTTGGCTACAGAAGTGCCCTGAGCCACTACCATG CTGACTGTAAGCAGAGGAATGTCCTGAGCCAGACTCATGTTGACCAAAGACAGAAGAGTG ACCCGAGCGAGACTCATATGGGCCACGGCTGGAAGAACGACCTGAGCCAGACCCATGTTG GCCGTGGCTGGAGGAGTGCCCCAAACCGGACCCATGTCGGCCGCGGCTAGGGGACTGGCC AGATCCAGACCCTTGTCGGCCGTGGCCCGAAGACTGACGGGAGCCAGACCCATGCTGACC ATAGCGGGAAGACGAACGTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGA TCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCCAGACCCATGCTGACTGTA ACTAGAGGACTGCCCTGAGCTAGACTCGTGGTGACCAAAGCCAGAAGACTCGCCTAAGCC AGACCCATGTTGGCCACTGCTGGAAGACCGACCGGAGCCAGACCCATGTCGGCCGTAGCT GGGAGACTGCCTTGACCCAGACCCACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGA GCCCTGTCGGCCATAGCCAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGA AGACTGACCTGAGCTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACC ATGTTGCCCATGGGTAGAGGAATGACCTGAGCTAGATCCATGTTGACCGTAGCCAGAGGA CTGTCCTGAGCGAGACTCTCGGTGACCTAAGCCAGAAGAGTGACTGGAGCCAGACTCATA TGGGCCACGGCTGGAAGACCACCCTGAGCCAGACCCATATGGGCTGTAGCTGGAAGACTG CCCAGAACCAGACCCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCC ATGTTGGCCGTGGCCCAAAGACTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGA TGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTG TTGTTCGTAGCTGGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGCAACCAGAGGACTG CCATGAGCTAGACTCGTGGTGACCAAATCCAGAAGACTGACCTGAGCCAGACCCATGTCG GCCACTGCTGGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC AGAACCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGCCCCATGTCGGCC ATAGCCAGAAGACTGACTGGAGCCAGAGCCACGGTGGCCATAGCTGGAAGACTGGCCTGT GCTAGATCCCTCCTGGTCAAAGGTTGATGACTGTCCTGATGTAGAACCATGCTGTCCTTG GCTACAGAAGTGCCCTGAGCCACTACCATGCTGACTGTAAGCAGAGGAATGTCCTGAGCC AGACTCATGTTGACCAAAGACAGAAGAGTGACCCGAGCGAGACTCATATGGGCCACGGCT GGAAGAACGACCTGAGCCAGACCCATGTTGGCCGTGGCTGGAGGAGTGCCCCAAACCGGA CCCATGTCGGCCGCGGCTAGGGGAATGGCCAGATCCAGACCCTTGTCGGCCGTGGCCCGA AGACTGACGGGAGCCAGACCCATGCTGACCATAGTGGGAAGACGAACCTGAGCTAGATCC GTGTCGTTCACCCCTAGATGACTGTCCTGATCTAGAGCCGTGTTGTCCGTAGCCAGAGGA GTGACCTGAGCCAGACCCATGCTGACTGTAACTAGAGGACTGCCCTGAGCTAGACTCGTG GTGACCAAAGCCAGAAGACTCGCCTAAGCCAGACCCATGTTGGCCACTGCTGGAAGACCG ACCGGAGCCAGACCCATGTCGGCCGTAGCTGGGAGACTGCCTTGACCCAGACCCACGCTG GCCGTGGCCTGGAGACTGGCCAGATCCAGAGCCCTGTCGGCCATAGCCAGAAGACTGACT TGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGAGCTAGCTCCATGTTGGCC ACAGCTCGATGACTGTCCTGATGTAGAACCGTGTTGCCCATGGGTAGAGGAATGACCTGA GCTAGATCCATGTTGACCGTAGCCAGAGGACTGTCCTGAGCGAGACTCTCGGTGACCTAA GCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCTTGAAGACCACCCTGAGCC AGACCTATATGGGCCATAGCTGGAAGACTGCCCGGAACCAGACCCATGTCGGCCACGGCT AGGGCTAGGAGACTGGCCAGATCCAGACCCATGTTGGCCGTGGCCCAAAGACTGACGGGA GCCAGACCCATGCTGACCATAGCTGGAAGACGAACCTGAGCTAGATCCATGTTGTTCGCT CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTTCGTAGCTGGAGGAGTGACCTGAGCC AGATCCATGCTGAGTGTAACCAGAGGACTGCCCTGAGCTAGACTTGTGACCAAAGCCAGA AGACTGGCCTGAGCCAGACCCATGTCGGCCACTGCTGGAAGACCGACCGGAGCCAGACCC ATGTCGGCCATAGCTGGGAGACTGCCCTGACCCAGACCCACGCTGGCCGTGGCCTGGAGA CTGGCCAGATCCAGAGCCATGTCGGCCGCGGCCCGAAGCGTGATGGGAGGCAGACTCATG CTGACCATAGCTGGAAGATTGACCTGAGCTAGAGTCATGTTGGCCGGAGCTTGATGACTG CCCTGACGTAGATCCATGTCGTCCCTGGCTAGAGAAGTGACCTGAGGCAGAACCATGCTG ACTATAGCCCTGTCCTGAGCCAGACTCGTGTTGCCCAAAACCAGAAGCCTGGCCTGAGCC AGACTCATAATGGCCACAGCTGGAAGAACAACTTGTGCCAGACCCGTGTTGGCCGTGGCT GGAGGAGTGCCCTGAACTGGACCCATGTCGGACACGGCTAGGAGAGTGGCCAGATCCAGA CCCTTGTCGGCCGTGGCCCGAAGATTGATGGGAGCCCGACCCATGCTGACCATAGCTGGA AGACAAACCTGAGCTAGATCCGTGTTGTTCACTCCTAGATGACTGTCCTGACCTAGAGCC GTGTTTTCTGTAGCCGGAGGAGTGACTTGAGCCAGATCCATGCTGACTGTAACCAGAGGA CTGCCCTGAGCCAGACTTGTGACCAAAGCCGGAAGACTGGCCTGAGACAGACCCATGTGG GCCATTGCTTGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC AAAATCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGAGCCCTGTTGGCC ATAGCGAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGA GGTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACCATGTTGCCCATG GGTAGAGGAATGACCCGAGCTAGATCCGTGTTGACCGTAGCCAGAGGACTGTCCTGAGCG AGACTCTTGGTGACCTAAGCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCT TGAAGACCTCCCTGAGCCATACCCATGTGGGCCATAGCTGGAAGACTGCCTGGAACCAGA CTCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCCATGTCGGCTGTG TCCCAAAGATTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGATGAACCTGCACT AGATCCTTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTCCGTGGCC GGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGTAACCAGAGGAATGCTCTGAGCTAGA CTCGTGGTGACCAAAGCCAGAAGAGTAGCCTGAACCAGACACATATGGGCCACTGCTGGA AGATCGACCAAAGCCAGTCCCATGTTGGCCGGAGCTGGGAGACTGCCCTGACCCAGACCC ACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGAGCTGTGTTGGCCGCGGCCTGAAGA GTGACGGGAGGCAGACTCATGCTGACCATAGCTGGAAGACTGACGTGAGCTGGAGCCATG TTGGCCAGAGCTTGATGCCTGCCCTGACGTAGATCCATGTTGTCCCTGGCTAGAGGAGTG ACCTGAGCCAGAACCATGCTTACTATAGCCAGAGGACTGTCCTGAGCCAGACTCATGTTG CCCAAAGCCAGAAGTCTGGCCTGAGCCAGACTCATAATGGCCACGGCTGTAAGAGTAACT TGAGCCAGACCCGTGTTGGCCGTGGCTGGAGGAGTGCCCCGAACCGGACCCATGTCGGAC GTGGCTAGGAGACTGGCGAGATCCAGACCCTTGTCGGCCGTGGCCCAAAGACTGACGGGA ACCAGACCCATGCTGACCATAGCTGGAAGACGAACCTGAGCTAGATCTGTGTCGTTCACC CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCC AGATCCATGCTGACTGTAACCAGAGGACTGCCCTGAGCTAGACTTGTGTTGACTAAAGCC AGAAGACTGGCCTGAGCCAGACCCATGTGTGTCATTGCTGGAAGACTGTCCGGAGCCAGA GCCGTGTTGGCCATAGTTGGGAGACTGCCCTGACCCAGACCCACATTGGCCGCGGCCTGA AGACTGATGGGAGTCGGAGTTTTGCTCACCATAGCTGGAAGACTGACCTGAGTAGGAGTT ATGTTGGCCAGAAAAGTCTCTTTGAAAACTCAGTCTTCTGGATATGGATTCAGTCCCAGG TTTAAGACTTCCTCTGACGTTTCTGGAATAGGAATCATTCTCTCCTGCACTCCAACTTGA ATGACTAAAAGAGGATTCTTGCCGTTTGTTCTCCTCTTTTTCAGTTTCTTCTTGTTCCTC TTGGTGCTGGTGAGTGTCATCTCTCAGCTTTGACCCTGAAACTTGGCAGTAATCTTTGCC AATGATTTTATTACGAGCCTGAACCAGCTTGAATATCATCAGAAGATACTCAGTAAAATC CACTTTCTTGTTATGGTCTCGATCCAGACTTTGCAAGATGATATCCACAGTATCTGGATC GTTTGGATTCTGTATAAGAGAAAGGTACAAAGAGTAGCTCTGTTAGTATGGACAATACAT CTGGCTAACGAACTGAAGGAAAGATGTGAAAATGTAAATGTTTGGGTTATTTATATGGAA CTCATTCACACAGTCCTTTAGGCTGCATTTCTGTATCCTGAGCAGAAAGAGAAAAAGGAA TATGGAATGAATAATGTGGTGGGAAACAGCTAGAATAGGATGCAACTGGAAGATGAAAGG AAACAAGAGGGCTGATTATTTTTGGTAAAGAATGGGTCAAATATGAATGATTAGCTAATT TATAAGTAATATGTTTTTATACCTACATTAATTATATCAACTTTATTTATCCAATTAAAT TAACTAGCTACTTAATTTACTCACTGAACAAAGATTTATTATTTTACTAGTTGCCTACCA TTATGTCATATGAGAGTATAAAGAAGTGAACAAGTTTGCTTCCTGAAAAAAAATGGAATT TAAAGTTTAGTTGGCCAGATATACAAACTTAAAATTATAATTTATTGTGGTAAGGTTTCT ACAAGAGTACATCAGAGAGGAAACATTGGGGGTCCTAGAAAGGTTAATGAGAGGAAATGA TGCCTTTTGAAGGATGGATTAGGATTAGCCAAATGAAGAAGTAGGAAGAGAAAGAGAAGG GGAAAAGATTGTTCTAGGCAGAGGGAATTATATGAACAAAGGGCTAGAGGTGAGAGAAGT TATGGAGCATTCAAGGAACTGAAGGAAATTCAGGATTGCTAGATTTAGAGTTTGAAGAGT CAAGAAATGTGGATAGAGAGACAAATAGGGACTAGATTATGACTTTTAAGTTATGTTAAG GAACTTTGTACTTCATTTTAAGAGCAATTGGGAACTATTGAAGGATTTTTAGCTGAGGAG TGAAATGATTATATTTGCATCCAATGCTGAGAGTAGAAGTAGTAGGTGGCCTGAACCAGA GGACTAATAATAGTGATGAAGAGAAATGGGTTGTTTTGAGAGATTATTGATGAGTTAGAT GGAGGTTAGAAGGTAGTGGTGTCTGCTGAGAGAGAGACAATAAAAAATGACACCAGGTTT TTGCTTTGGGCAAAAAGATGAAGGAAAAAGGTTAGTGGGGAAGATTATGAGATTCATAGC TGACACACTGAATATCTGACATCTGATATCTGAATATCATATCTGAAATCCACAGAAATC CAAATTTAAGGAATTGAAACTCAGGAGTCTGATATAAGGTCCCAAATATCTAAGCTATCA AATCTAGACCTGACAGTTTTAAGGTGGTGGACACATTCTTTTGTGATTCAGGAGTAAATG CCAATTTCCTGAACTCAGAAATCTACTTCACAGTTTTTCTGAGGACTGTCTGGGTTTGTA GGAATTAGTCACTTAGATAGGACATTATTTAACCTGTGGGTTTTGTTTGTTGTTTAGTAA GGTCACTTCCGTTAGTTATGCTATGGAAACCATCACGGATCTGCTTTTGACCTTATCTCA AACTTTTACCAAACCCTGTTCTCTCTCACCAAGTAAGGACAATCCTCTAGGATGTTTGAC ATATGTGACAAGAAGGTGGAAAGGGATAAAGAAGAAAATTCCTGCATAACTCCATCCTGG CGTGGAGTTCTTACCTTCAGAATTTGATGAAACTCATTTTCCAGAAGTTCTTTCAGCTCT GCCTTGTTCAACGTATCATACTCCCCATGCTGGGTGGCATATTGGTAGAAAACATCGATG ACAGTGATGACGCCTTGTAGGAGTTTAGGCATTTTTTTTTTTGCAAGTTTGAGTAACCTA AAGGGAGGAAAAAGAGAGACCAACCCCTTACTATTCTTATTTCTTGTTTAAACACATAAA TAGTTCTAATTATTTATAATAATTGTTCAGAATTAGTCAGTCATGATTAAATTCATTCTG TTGTAATCAAGAACCAATTCAGAGTTGAATGACTTGTTCAAGCCATGTAGCAAGAGAGTG ATGAAATTAGGAATATAATCCATAGGTCTTATTTCCATTCCTGAATGAATGTAGGAAAAA TGACTTTCTGTTTTTGGCTTCCTGCCATTACCAGGGATAATATTAGCTTTGTTCTGGAGC TGTAGAAGTCCTGAGTGTTCCACTTCATCTGCTTCCTCTTTCTAGGTTCGAAGCATACTG TGGGCATAGGTCCATCATCTACATGACATGCCTTACTCAACCTAAGGAGCATCAATGGCT GAACTGAACTCTCAAGACTTCTAGGTCAGAGAAAATAGACAATGTGAGCAAAGCCAACAA GCCTAGGTGATATGAAGCTAAGGGTAACTGCTATTAGATCCAGCTTCTGTTCTCATTCTC CAAGCAGGAAGTGACCCTCAGACCTTATTACACAATAGAGAGGAAAAGCTCAGTTGTAAA GAAGGCAACCTGCCTGTGGATAATTAGAACCCCATGATATCCATGTTATAAGGGAAGCGA CCTCAAAGAAAGGAGATAATATACATAGTCCTAGTCTTTGTTTCATTTTTCTTTTCAGTA AATTTAAACTTATACCAAAGTTCCCCAGAGTATACTAAAAAGAAGCCTTGTATCTAGTGC CTCTTTGCCTTAGAGCACATCCTGGACTTTCATAATTTATAGCCCTAAGTACCCTTGAGC GGAGTTGAACTGCTCACTTACCTAGCTCACCAGAGGAACAAGTAGGGTAGAGACAGAAAC AGCTTTCAGGGTGCTGCGAGTTGGGCAGAGTG bcftools-1.21/test/csq/ENST00000368801/ENST00000368801.fa.fai000066400000000000000000000000211467060157400215340ustar00rootroot000000000000001 12152 25 60 61 bcftools-1.21/test/csq/ENST00000368801/ENST00000368801.gff000066400000000000000000000027701467060157400211670ustar00rootroot000000000000001 ensembl_havana gene 21 12132 . - . ID=gene:ENSG00000197915;Name=HRNR;biotype=protein_coding;description=hornerin [Source:HGNC Symbol%3BAcc:20846];gene_id=ENSG00000197915;logic_name=ensembl_havana_gene;version=5 1 ensembl_havana transcript 21 12132 . - . ID=transcript:ENST00000368801;Parent=gene:ENSG00000197915;Name=HRNR-001;biotype=protein_coding;ccdsid=CCDS30859.1;havana_transcript=OTTHUMT00000034016;havana_version=1;tag=basic;transcript_id=ENST00000368801;version=2 1 ensembl_havana three_prime_UTR 21 1014 . - . Parent=transcript:ENST00000368801 1 ensembl_havana exon 21 9429 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447986;constitutive=1;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001447986;rank=3;version=2 1 ensembl_havana CDS 1015 9429 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 1 ensembl_havana CDS 11055 11192 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 1 ensembl_havana exon 11055 11217 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447987;constitutive=1;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001447987;rank=2;version=1 1 ensembl_havana five_prime_UTR 11193 11217 . - . Parent=transcript:ENST00000368801 1 ensembl_havana exon 12082 12132 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447988;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001447988;rank=1;version=2 1 ensembl_havana five_prime_UTR 12082 12132 . - . Parent=transcript:ENST00000368801 bcftools-1.21/test/csq/ENST00000368801/ascii-art.txt000066400000000000000000000010311467060157400212620ustar00rootroot00000000000000 1 4310 . A G . . EXP=@11191;type=ENST00000368801:152188847-A-G 1 6298 . G A . . EXP=@11191;type=ENST00000368801:152190835-G-A 1 11191 . AT A 1 ensembl_havana CDS 1015 9429 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 1 ensembl_havana CDS 11055 11192 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 11191 eeeeeeeeeee.......... AGTTTAGGCATTTTTTTTTTT AGTTTAGGCA-TTTTTTTTTT bcftools-1.21/test/csq/ENST00000368801/compound-lost.txt000066400000000000000000000006771467060157400222300ustar00rootroot000000000000004310 A G missense|HRNR|ENST00000368801|protein_coding|-|1753V>1753A|4310A>G 4310 A G missense|HRNR|ENST00000368801|protein_coding|-|1753V>1753A|4310A>G 6298 G A synonymous|HRNR|ENST00000368801|protein_coding|-|1090G|6298G>A 6298 G A synonymous|HRNR|ENST00000368801|protein_coding|-|1090G|6298G>A 11191 AT A synonymous&start_lost|HRNR|ENST00000368801|protein_coding|-|1M|11191AT>A 11191 AT A start_retained|HRNR|ENST00000368801|protein_coding|- bcftools-1.21/test/csq/ENST00000368801/compound-lost.vcf000066400000000000000000000011421467060157400221530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 4310 . A G . . EXP=missense|HRNR|ENST00000368801|protein_coding|-|1753V>1753A|4310A>G 1 6298 . G A . . EXP=synonymous|HRNR|ENST00000368801|protein_coding|-|1090G|6298G>A 1 11191 . AT A . . EXP=synonymous&start_lost|HRNR|ENST00000368801|protein_coding|-|1M|11191AT>A;type=ENST00000368801:152195728-AT-A bcftools-1.21/test/csq/ENST00000373833/000077500000000000000000000000001467060157400166535ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000373833/ENST00000373833.fa000066400000000000000000001022211467060157400210050ustar00rootroot00000000000000>1 1:28832455-28865812 GATTCTCTAACTGCGCATGCTTCTGCGCACGCGCAATAGACATTCCAGGACTTCCGGGCA CTTCGTAAGGTTTAAAAAGGATGCTTCGCGTTTTCTCTCTCCTTTTTGGAGACAGATTCG CAGTGGTCGCTTCTTCTCCTTGGTAAGTGTGATCCTTGGTAAGTGTGATCAGATGCTTGC CACCGGAGTTGTGGGTCTAATGCTATAGATCAGTAGCCGAGCTTCCCTAGGAAGATCATA TAGTATTTTATTTATTTACTTTTTTTTTTTTTTTGAGACGGAGTCGGTTTGTCACTCAGG CTGGACTGCAGTGCTCGTTGCAACCTCCGCCTGCCGGGTTCAAGCGATTCTCGTGCCTCA GCCTCTCCAGCAGCTGGGATTACAGGCACGTGCCACCACGCCCGGCCAATTTTTGTATTC TTAGTGGAGACGGGGTTTCGCTATGTTGGTCAGGCTGGTTTTGAACTCCTGATTTCCGGT GATCCACCACCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCTGG CCGGAAATCATGTAATTTAAAACTATATATGGGTGTCTTAGGCGGCATCGGTCCCAACTC TAAAGTACGCGTTAGACGGGCCTGGGCCAGAAGTGGGCCATGGAGACCTCGGGACCCGCA GGGCTGCCGCCCGACCCAGCGAGCCTCTGAAGGTGCACCGCCACCCCCACTGTTTATCTT ACTGCCTCATAGTAGGCACATTGTCGTTCTCAATATAATTGCACACAGTTTTATTCTGGA TCCTCATTTGCCTTTAAGAATTTTCTCAATTTTTCTTTTTATTTGATCGCACCACTGCAA CCTCCGCCTGCTGGGCTCAAGCAATTCTCCTGCCGCAGCCTCCCGAGTAGCTGGGACTAC AGGCGTGTACCACCGCGCCTGGCTTATTTTTGTATTTTTAGTAGAGACGGGATTTCACCA TGTTGGCCAGGCTGGTCTCCAACGCCTGACCTTGTGGTCCGCCACGCCAGGCCGAAGATT TTCATAATTTGGAAGCATTGCGTTTCGTAATTATGCTTTCTCGTATTTTTGTGATTTGGG TCATTTTTATTTTTATATTTTTAGGATTACAGGCGTGAGCCATCGTGCCTGGCCGATTTG GGGGTAATTAACAAGTCCACGTGTTTCATTTGAATTTAGGATAGCTGGGCCTAATTGTTG TCTTTGCTTCTGCGGTACCTTCCACATAGTACTAACCGCCTATTGTAAAGTAATTAGAAT AGCTGAATATGCATGTTACCAGTCTAGAAACCGATTTTTTTTTAACACCCCACTGTGGAC AGGGTGGAAACTCGTTTGCTTTCTTGTTTAAGATCTGTAGTAACATGAATGGATGAAATT GTTTCCTATTGGATTCTGTAAATTTATGCGTTACACTGATTGTCCAACGTGGATACACCC GGGAGGTCACTCTCCCCGGGCTCTGTCCAAGTGGCGTAGGGGAGCATAGGGCTCTGCCCC ATGATGTACAAGTCCCTTTCCACAACGTTGGAAATAAAGCTGGGCCTCGTGTCTGCGCCT GCATATTCCTACAGCTTCCCAGAGTCCTGTCGACAATTACTGGGGAGACAAACCATGCAG GAAACAGCCTTCTAGAGCACTGAATCTGGATTGAAGTCTTTTTTTTTTTTTTTTTTTTTG GAGATGGAGTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCACTCCATTGCCTCTGCC TCCCGGGTTCAAGTGATTATGCTAAGTGATTCTCCTGCCTTGGCCTCCTGAGTAGCTGGG ATTACAGGCCCCCGCCACCACGCCAGGCTAATTTTTGTATTTTTAGTAAAGACAGGGTTT CACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTTGTGATCCGCCAGCCTCTGGCCT CCCAAAATGTTGGGATTACAGGCGTGAGCCACCACACCTGGCTGGATTGAAGTCTTAATA CATGTTTAAGAAAAATTGGCTAAAAAGTAGCCAGGCATGATGATAGGTAGCTGGAGGAAG GAGAATCGCTGGAGCCCAGGAGTGACCTATACTCAAACCTATACTCCAGTGCCACTGTAC TCCAACCCCAGGCGATAGCATGAGGCCCCTCGTTGAAAAAGTTTAGGGTTTTGCTGTACT AATAGATTAATATCTTGTTTTGCAGGATTTGTTAAGGATTCCAAGTAACTCTTATTTGGT GAGTAAATCTGCTAATTGTTTTTTGCTTATCAGCTCTTTGTCAATGATTTCTGTAATGGA AATAGGATTGAAGAGACTTTTATTCTAGTTGGTCAGGATTTACCTCTGAGGCATTTAATC ATTCTCAGAGCAATAGCCAAATATCGACTTTGCTGCATTTTTGTAGGCATGTTGACATAA CTTCAACATATGCTCTGTTCTGTAAAAATTGCTTTTTTTAGTCAGCTCATTAAAAGTGCA AAGTAGTAAAAGCTGCCCTAGTGAACTGTAGGAAGCCTAATTGGCTTTATCTACATGTGT AGCCTGAGCTGAGAAAGATACTAGCCCTTGAAAATACTGTGGGTGATTAGCAATATTGGA TTTGTCGGTTACTCCAATTCCTCACTAATGAGCATTCCAACGTGGATACCCTGGGAGGTC ACTCTCCCCAGGCTCTGTCCAAGTGGCATAGGGGAGCTTAGGGCTCTGCCCCATGATGTA CAGTCCCTTTCCACAACGTTGAAGATGAAGCTGGGCCTCGTGTCTGCGCCTGCATATTCC TACAGCTTCCCAGAGTCCTGTGGACAATGACTGGGGAGACAAACCATGCAGGAAACATAT CTAGTATACTAGATTTTAAGTTGAAGTAGGATCTTCAGGAGTCTAATCATTATTTCTTTT CTTTTAGGAGAGAAGACGATCTGCACTTCGCATTTTGGCATTGACATTTAATTTTAGGGT CCTTTATATAGAAGGGAGAGTAGGTAAACTGATTTTTTTTTTTAACAGGGAGGGTTTGAC AATCTTTGGCAGACTTGGAGCAAAAGATTGAGGTGCATTTCATGCCTCCTTTTGAGAGTC TTGCTCTGTCGCCCAGGCTGTAGTGCAGTGGCGCAATCTTGGCTGCAACCTCAGCCTCCC AAGTAGCTGGGATTACAAACATAAGCCACCACGCCCAGCCCTCATACCTCTTTTAAAAGT CGACCTGTTTTGCAGAAAGTCTGCTGTTTTTGTACTAAAGGCTTTGGAATTTGGCATTTA GCTAGGAATGCACATTCTTTCACCTCATTCATACTTTAAGAACCACAGAAGTGACTCTGC TTGGCCAGAAGGCACACTGTGTTGGTGGTTATATTAAAAGTCCTTGAGTATTTTGCTTTT CATGATCTTGCTCACTGCAACTTCCGCCTCCCAGGTTCAGGCGATTCTCCTGCCTCAGCC TCCCAAGTAGCTGCGACTACAGGCGTGTAGCACCACACCTGGCTAATTTTTGTATTTTTA GTAGAGATGAGGTTTCACCATATTGGCCAGGCTGTTCTCAACTCCTGACCTCGTGATCCG CCCACCTCAGCCTCCTAAAGTGCTGGGATTACAGCTGTGAGCCACCCTGCCCGGCCACTT TTGTATGATTTCTAATGTATTTGTAATTTACCTAACAAATTGCCTAATCTGCTATGTTAA TGTATTTATGAATTAAAATAAATACGACTGCATGTTTGTGGTTCATTTTTGTGGAGGTGG CTGTGGTGACATCAGCCAAGAATCTGAATGGTACTGTTGAAGGAAACTAGCATGATAGCT TCAGTTCTAAAGGCCCTGAAACCTAGTCTCAGGTGGGTCCCCCTTGGGTTCACTTTATAT TGGCAGTTTATTGGGAAAATGGATATTAGGTCCTGACCAATAGGACCGTAAGTCTGGGTT GAGTGCAAGATGAGTTAGACCGATTCTTTAGCTTCCTGCAGTGTAGTGGAGGAAAAATCG ATGGTAGCAACGGGAGGTTGTATCCCTAGCTGATGAGTTGTATGAGCCTCTACTACCTGG CGCACCTCCGCCTGAAGATTGCCAGAATTGCTTGCCTCATGACGTGAGTCACAATGGAAA CTTTGTCAAGCCCCCTGCACTGGCTGCCAACATAAATGTTCAGTACCCTGAAGGATGGGA CTGAAGGGGGATCATCTAGAAGGTAAAGTTACCTACTGGCATAGGGGAGGTGGGACAGCC GTTAAGCCATTTGGAACTTGATGGAGACAGGTTTGAGGGAGGTGGGTGAGATTGGAGTTT GGTGGACTGTAGAGCTTGCTTGCCAAGGTGTTGAGGTCAGGGTTGGTTTGAGAATGGAAG CTAGTTACTAGCTATGATTGTGGGGGAACACAGCTTGATTTTTCTTACAAGCTAAGAGGA GTGAGGCAGTGTTTAAGAGGGCATGTTAAATGCAGCCAGGCTTGGTGGCTCACACCCGTA ATCCCAGCACTTAGGCTAAGGCAGGCGGATCACAACATCTAGAGATCCTGGCCAACGCGG TGAAACCCTGTCTGTACTAAAAATACAAAATAACTGGGCATGGTGGTGTGCACCTGTGGG AGGCTGAGGCAGAATTGCTGGAACCCGGGAGATGGAGGTTGTACTGAGCTGAGACCTTGC CACTGCGCTCCAGCCTGGTGACAGAGTTAAGTCTCAAAAAAAAGGCATCTTCCTAAAGCA ATTGTATTTGTGCTTACCTGTGCCAGGCACTGTTCTAGGTAAGCACTAAGTGGGCTTTAA TACAGCATATTCCAATGGGGAATCCCAGGAACCAAAAGACTAATTGTCCAAGTCCACAAC TAGAAGTGGCACCTCTGCAGAAACAAGCATCAAATTCCCTGCTCAGGAAGAAGCCAGATG AGTCAGCCCCATTCGTCTGTATGCCCAGTCCCATCCGTGTCCTGCTGTAACTACATAGAT CTCACCTGAGTAAAGTGATTTTTTTCTGAACCAGTGGTTTTAGTATGTTTTCAATCCATA TACTCAGGTGGGTTTGGGTAACTGCAGTGCTGGGCAGGAAATGAATGAATTTCTATTGAC TTGCAAGGTAGAGGTGAAGCAAAGCTGTCAGTAGGTGTTCAGGTCCCACTCTGCTAAACT TCAGCTTGCAATACCCCTTTTTTAGACTTTCCAAACAGGCACTTCTGGCCTTGTTCTTTG TGTAGGCAGACAGTATTGGTTGCCTATCTTAGGAGTACTAGACTGGGTTTGAATCCTGAT CCCACCACTTGCTGTTCATGAGACTTTGGGTGAGTTACTCAGCCCCTCTGCCTCAATTTC ATGTTCACAAAATAAGTGATAAACTACCTCATAGAGTTGTAATAAGGACAAAGGAGTTGG TATTTGTGAAAAGATTCTTAGGGTCTCTAGATGGAGTGCAGCAGCATGATCACTTATTAA ATAACATTCTTTTGTGACTTCTCAGAAACCAAGGATACAGTATCCAATTTTTTGTTTTTT GTTTTTTTTTTTTTTTGAGAGGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCA CAATCTCAGCTCACTGCAAGCTCAGCCTCCCCAGCAGCTGGGACTACAGGTGCACGCCGC CACACCCGGCTAATTTTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCATGTTAGCCAGG AAGGTCTCCATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGTTT ACAGGCGTCAGCCACCATGCCCAGCTTTTTTTTTTTTGAGATCTAATCTCACTCTGTCTC CAGGAGGGAGTGCAATGGAGCCATCTTGGCTTGCTGCAACCTCCACCTCCCGGGTTCCAG CAATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCACGCCACCATGCCCG GCTAATTTTTTTTGCATTTTTTAGTAGAGACGGGTTTCACCATGTTAGCCAGGCTGGTCT CGAACTCCTGACCTCAAGTGATCCACCTGCCTCAGCATCCCAAAGTGTTGGGATTACAGG CGTAAGCCACTGCGCCTAGCCTCAAGCCTGATCCTTTTTTTTTTTTTTTTTTTTGAGATG GAGTCTTTGCCTCCCAGGCTGGAGTGCAGTGGCGTGATCTCAGCTCACTGCTACCTCTGC TTCCTGGGTTCAAGCGATTCTCCTGCCTCAACCTCCCAAGTAGCTGGGATTACAAGCGCC TGCACCGCACCCGGCTAATTTTTGTGTTTTTTTTTTCAGTAGAGACAGGGTTTCGCCATG TTGGCCAGGCTGGTCTCAAAACTCCTGACCTCAGGTGATCCACCACGCCCGGCAGAGCCT TGATCTCTTAACCACTATCCTCACCTCCCCTTTCCCTAAGGATCCACAATGGCCTCACTG GCTCTTGAAGGCAGGCTGGCACCTTGATCATTCTTCCTGGTCATTAGTATTCTGATCTGG TTATTTTCCATTTTATGTCCATCTAACCTACTTGGAGGATCCTCAAGAGACTGCATATGT AAACTCAGTACTTATTCTTGTACTGTGCCTGCCATATAGCAAGCACTGGCTGATTTAATT TTTCTGTGTTCTTTTTTATTGATTTGTTTTTATCTTTATTATTTTCTTTGCTTATTTTGG GGTTAGTTTGCTCATCTATTCCTAGTTTCTTAAGCTAGTAGCTGAGCTCATTGATTGGAG ACCTTTCTTTTTTTCTAATGTAGGCATTTAGTGCTATAAATTTCCTCCAGATACTGTTAA CAACACACAAATTCTGGTATGTTTTGTTTTCATTTTAATTCATTTCAAAATATTTTTGAG TTCCTTTTCTATTCTTTGATCTATGGGCTACTTGAAAGTGTATTATTGTTGTTGTATTAG TGTTGTTCAAATCTATCCTTGCTAGTTTCTTTTTTTTTGGAGACTGCGTCTCCAAAGGCT GGAGTGCAGTGGCACAATCTTGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACACCATTC TCCTGCCTCAGCGTCCCCAGCAGCTGGGACTACAGGTGCCTGCCACCATGCCCTGCTAAT TTTTTGTAGAGATGGGGTTTCACCATGGTCTCAATCTCCTGACCTTGTGATCCACCCGCC TCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCCAGCCTCTTTTTTTT TTTTAGACAAGAGTCTCACTCTGTTGCCAAAGCCAGAGTGCAGTGGCACAATCTCAGCTC ACTGCAACTTCTGCCTCCGGAGTAGCTGGAATTACAGTCACGCACCACCACGCCCAGCTA ATTTTTTTGTATTTTTAGTAGAGATGGGGTTTGCGCGGCTGAAGTGCAGTGATGCGATCT CAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCATGCCTCAGCCTCTGGAG CAGCTGGTACTACAGCATGCACCACCATGCCTGGCTAATTTTTTTGTATTTTAGTAGAGA TGGGGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTGAGCTCAGGCAGTCCGCCTG CCCTGACCTCCCAAAGTGCTAGAATTACAGGCATGAGCCACCGTGCCTGGCCTTATTTTA AAATTTTATTTCTTGTAGGTAACATGTTGGGTTTTTCAGTATGACAGTCTATGTCTTTTA ATTGGAGTGTTTAGGCTATTTACTTTTTTTTTTTAAGACAGGGTCTCACTCTGTCACCCA GGCCAGAGTTCAGTGGCAAGATTATGACTCACTGCAGCCTTAAACTGGAACTCCTGGGCT CAAGCCATCCTCCCAGCTCGGTCTCCTGAGTAGTGAAGACCACAGGCATGTGCCACTATG GCTGGCTAAATTTTGTATTTTTTGTAGAGACAAGGTCTCATGATGTTGTCCCAGCTGGTC TTGACCTCCAGGGCTCAAGCAATCCTCCCACCTTGGCCTCCCAAAGTGCTAGGAATACAG GCATGAGTCACCATGCCCAGCCATATTATACATTTTTAACTTACAATAGTCCACATTCAA TTGATATTAAACCAGTTCACTTGTAGTATAAGAATCTTCCCCAGCCTGGCCAATATGGTG AAACCCCGCCTCTACTAAAAATACAAAAAAAAAAAAATTAGCCAGGTGTGGTGGTGCTCG CCTGTAGTCTCAGCTACTTGGGAGGCTGAGGCAGAAGATTGCTTGAACCTGGAAGCAGAG GTTGCAGTGAGCTGAGATCGTGCCAGCCTAGGCAACAGAGCAAGACTCCGTCTCAAAAAA AAAAAAGGCGGGGCCCGGTGGCTCACGCCTGTTATCCCAGCATTTTGGGAGGCCGAGGCG GGCGGATCACGAGATCAGGAGATCAAGACCGTCTTGGCTAACACGGTGAAACCCCATCTC TACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTA GGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGTGGAGCTTGCAGTGAGCCAAGA TCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAACAA AAAAAAAACCTTCTGGCGGCCTGGTGTGGTGGCTCACACTTGTAATCCCAGCACTTTGGG AGGCTGAGACTGGCGGATCACCTGAGGTCGGGAGTACAAGACCAGCCTGACCAACATGGA GAAACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGCATGGTGGCACATGCCTATAAT CCCAGCAACTCGGGATGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCA GTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCA AAAAAAAAAAACAATCTTCCGGCTGGGCACAGTGGCTCACGCCTGTAATCCATCCCAGCA CTTTGGGAAGCCAAGGCAGGCAGATCACGAGGTCAGAGCGAGACTCCGTCTCGAAAAAAT AAATAAATATTTCTTCCATTTCTCACTATATAGTCTTTGATATTGTCATGTGTCTTACTT TTATATATGTTATAAAACCCACAGTACATTATTACAGCCAGAACCTCCATATCAGCCAGT TGCGATGGCTCACTCCTGTAATTCCAACACTTTGGGATGCCAAGGCAGGCTGACTGCTGA GGCTCAGAAGTTCAAGACCAGCCTGGCCAACATAGTGAAACCCTGTCTCTACCAAAAATA CAAAAATTAGATGGGCAATTAGCTGGACGTGGTGGTGCACGCCTGTAATCCCAGCTACTC GGGAGGCTGAAACAGGAGAATTGCTTGAACCCAGGAGGCAGAGATTGCAGTGAACTGAGA TCACGCCATTACACTCCAGCCTAGGCAACAGAGTGAGACTCCGTCTCAAAAAAAAAAATT AGCTGGGCATGGTGGTGCACATCTGTGGTCCCAGCTACTCGGGAGGCTGAGGCAGAGGTT GCAGTGAGCCGAGATCCTGCCACTGCACTCCAGCCTGGATGACAGAGTGAGACTCTTGAG ACAAACAACTGGGGCTGGGCGCAGTAGTTCACACGTGTAATCCCAGCACTTTGGGAGGCC GAGATGGGTGGATCACTTGAGGTCAAGAGCTCAAGACCGGCCTGGCCAACATGGTGAAAC CCTGTCTCTATTAAAAATACAAAAATGAGCCGGGCATGGTGGTGCGTGTCTGTAATCCCA GCTACTCTGGAGACTGAGGCAGGAAAATTGCTTGAACCCAGGGGGCAGAGGTTGCAGTGA GCCGAGATTGCACCACTGCACTCCAGCCTGGGCAACAGAATGAGACTCCATCTCAAAATA AAATAAAAAATACAAATACAAAACTAAAAAAATAAAAATAAAGGCCAGGTGCAGTTGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGATGGGCAGGTCACCTGAGGTCGGGAGT TCCAGACCAGCCTGGCAAAAATGGTGAAACCCGGTCTCTACTAAAAATACACAAAATGGC CAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGTAGGCTGAGGCGGGTGGATCA CCTGACGTTTAGGAGTTCAAGTCCAGGCTGGCCAACATGGTAAAACCCCGTCTCTACTAA AAATACAAAAATTAGCTGGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCAGGAGGC TGAAGCAGGAGAATTGCTTGAACCCAGGAGGAAGAGGTTGCAGTGAGCTGAAATCGTGCC ATTGCACTCTAGCCTGGGCGGGTCAGGAGTTCGAGATCAGCCTGGCCAACATGGAGAAAC CCCATCTCTACTAAAAGTACAAAAATTAAGGCTGGGCGCGGAGGCTCACGCCTGTAAGCC CAGCACTTTGGGAGGATGAGGTGGGTGGCTCATGAGATCAGGAATTCAAGACCAGCCTGG CCAAGATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCAG GCACCTGTAATCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGCTGC AGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACCCCATCTCA AAAAAAAAAAAAAAAAGAGTTGAGGTCTCCTTCCACCACTTGTGTGAAGACCCCAGAAAA CTTGCTTTACCTCTTTAAACTTCAGTTTTCTTATCTTCCAACTGCCATGAGGTTTTTGTG AGGAACAAATGAGCTGACATGGATGTTTCTGTAGTTAACAAAATAAAGGGTCTTACAAAA TAGGCAATAATAATAATAATCACTTATTATTATTACATGAAGCTACATGAATGTGTAAGA TCTTGGAGGAAGACAGCAGAGAGAGAGAGAGAGATCAGAGATCCCAGGGTTAAAAGTTGG AGAAATTTCACAGTACATCATCCAAAAGAGGAGTCCATGATGGAGGCAGAGGTAAACTTG GAGAGGTAAGAAACCCTGAAGACAGGGGAGTGCTTTGTGGCAGGCTCTGCATATAAGAAT TCAGCCTGGCCAACATGGCGAAACCCAGTCTCTACTAAAAATACGAAAATTAGCCAGGCT TTGTGGCAGGCACCTGTAATCCCAGCTATTTGGGAGGCTGAGGCAGGAGAATCGCTTGAA CCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCTCACCATTGCACTCCAGCCCGGGTGAC AAGAGCAAGACTCGATCTCAAAAAAAAAAAAAGTTCAGTTCAGTTGGTAAGAACTCATCA AAAGTGTCCATCTAGACTTTGGGTGCCGTAGAATGACTCAGAGTCTGAATCAACATGAAA TCGAGAAAACGTCCTTTGCAAGGGTTTCAGGGAACACCTGAAATCCTGAAGAACTGTTTG TATCCATCCTGAAGAATGGGTGTTAATAAGAGACAGCCTTTTCTTGGTACCTGTTTTCCA TCTCTAACCCAACCCCAACTCACACCCTTCTATTTTATCTGGTCTCTCTCATTCCTCTTG CTCCTCCCCACTTGGCTCCCGTTTTCCCCAAGTCCATTCTCTATTTTGTTCTATAAGATC TGATCATATTAGGATGCTCTTGTAGCTCATAAGAAGATGACTGGGTGTTCACACGCATAT GAGATGTGCCTCCCTCAAACCTTGTTAAGACATGGGCACATACCCATCTGATGTTAACTC ACGGGGAAAAAAATCTGATCATGCCATTCCCGTGCCCAAATTCCCATATATCCCTACTGC CTCAGGATAGAGGCTGGACCCCTTAGACACACAAGACCCTGTATCCATGATCTGTCACTC CCACAGGCACCCTCTACTCCCATCTACTTGGCAGTTTCCCACAACCTCCCTGGGTTCTCG TGGTTCCCTGTCATTGCAAACGTCGCTTCTCCTAGGATGTCCTGCCCCCCTAGACTTAAC TTGGAAAGCTGTTCTTAAGCCCCGGACTGAGTCAGATGCCCCTCTGGGTATCCCTGTCAT AGCGTTGTGTGGTTGTTGATAGTCTGATTTTTCAACCTTCTCCATGCCCTCTTGAGGGTA GGGAAGATGAGTATCTTTTTTCTCCGTACAGACCCTACCGCACAAGATTTTCCTAAACAG ACCGAACTCAAGGAGTCTTTCTGGTTGTTAGTCCACGTGTCCCGATTTGGGGTTTCCAAA ATACACGCCCACTGGAACCGGGCCAGGGGAGCCAGCCTGGCCAAGGGCTCCCCCAGCCCG GCCAAGGGCTCCCCCAGCCCGGGAGCGCGCCACATGCAGATCCTGGGATGGCCGCCAGGG GCCGCCGGGCTCTTTGTTTTCCTTTCTCACCCGGGTCGGGGCCAGAGGCCTGCAGAGCGC ATGCTCTGGGGCAGTTCGCGGCCCGGCGGGGAGCGCCGGAGTTCCTTGTGGCCGACGTGC ACCAAGGTAGGTCTCGCCTGGGACGCGCGGAGGGTCCGGGCAGAGGGCGGTAAGCGGAGC GGCCACAGCCGGAGCACGGGCCGGTCCACGCGGGCCTAAGTCGCTGCCCGCTCTCGCCCG TGTCGCGCGGCGCCGGCCCCACGTGAAGCCCGGAGGCAGGAAGGCGCGGTGCGGGCTCGC GATTCCCCGGCCCCGCGGGGCGCTCCAGCAGCGGCTGGGCGCTGCCTCGCTGGAGCTAGG GCCGCGCGGCCCCTCCGCCGCCGCGCCTCTCACGCCCGCACCGCGGCGCCCGCGCAGGCG GGAGATTCAAACTGCGCGAGCGCGGCGGGCCGGGTGCGCGCGGCCGCCCGGGCGGGGGAT GGGTCTCTGCCGCGAGGAGGATGGTTTTGTCCGGCATGCGCTTGGAGAAGGCGGTTTGCA GATCGGGGAGGGAGCCCTGCCCGGGAGAGGGTGGGTCGTAGGAGCTCGAGGGTCTCCCGC TGTGGACCTTTGGGAGCCGTGTGTCTTGAACTCCGCAGCAGCTCAGTCTGTCAGCAGATT ATTTGCTGGCCATTTATTGCGTCCCTCTCTTGCGGGGCTGGGGGACAGTAGTGAGAAGAG CAGGCCCGTGTCATTAGCGAACTATGCCCTTGAACCCAGGCGACGGACGCTACTGGCAAG TCATTCATACGTCACATATTGACCTAACTTCGACCACGTGTGACTTGTGTGCCCTAGCAG AAGTTGAGTGTGTGGGGTGTTACGGGGAGCCCTCAGGGGGATCCCCCACCCTGCCCAGGA GGCTCAGGGATGGCTTTCCAGGTGAAGTGACTCTTGAATGGGGTTTTGAAGGAACAGAGT TTTTCAGGCAGTCTGAGGGTAGTGGGATTAGGGTGATACAGGCAGAGGGATTGCACGTGC AACGGCATGAAGGTATAGGTATTGTGGTCAGGGATACCACAGGTCTTGAGGTGACTGGAG GAGGAGAGTAACAAGATGATACAGCAGGGGCTGGGTCACGAAGCGTCTTGTGTGCAAGAC TAAGGAACTCTGCGGGGTGGAGGAGGCAGGGAAGATTTCCCCCAAGAAGGGTATCAGAGT GAAACCTGGACAGATGAATTAGGAGTTCACGAGGCTCCTGTTTCAAAGACATCCCAAGAG CAGGAATCCTGTTCTGTTCATCGTTACAACTTTCTCATCAGATGCCCTTGGGCAACCCAC CCAGTCCCCCAGAGCATTGGTTTCCTTATCTGTAAAGCAATGGTAGGGGGCATGTGGTGA GGATATAATTTTTTTTTTTTTGAGACGGAGTTTCCACTCTTATTACCCAGGCTGGAGTGC AGTGGCGCGATCTCAGCTCACTGCAACCTCCACCTCCTAGGTTCAAGCAATTCTGCCTCA GCCTGCTGAGCAGCTGAGACTACAGGAACACACCACCAGGCCCAGCTAATTTTTGTATTT TTTTTTTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGA CCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGAATTACAGGTGTGAGCCACC GCACCCGGCCAATTTTTTTTTTTTTTCTGATACAGAATCTTGGTCTATCGCCCAGGCTGT AGTATAGTGTCGTGCTCTCAGTCGCTGCAGCCTCCACCTCCCGGGTTCAAGCGATTCTCC TGTCTCAGCCTCCCGAATAGTAATATCCTATAATTTTCATAAAGCAGTGAAGTTGTGTGT CCCTTCCCCCAGGAAAAATGAACACATAGGCCCAGGCACAGGTTGTATAGAACGGGGATC CCAGGTGAGAAACTCCTAGTGTGAAATATACCACCTGTGTGCCTGGCATAACAGCAGCTC ACCAAATGTATATTGTTGACACATGAGCCCTCTCCTCCCTTCCCTCCTGGGGACCTTACA CACAGAGATTTTTCAGCCTTAGTCTGGCAGGCAAGTTCTTCCTCCTGGTGTGGGGGACGG AGGGCACAGCTGCAGTGGCCTGGGAGGGCTCTGTCTCCTTTTACAGAAATCGAGGCTGTG GTGAGGTCACTGGAGGTCAGGGCAGGAGCACCAGGCTCCGGGCAGACTGTCTAGACTGGC GTGCCTACCCACTTTCTTCAATAAATAAGGAAGGTGAGGTGGGGGTAGGGCAGCTCCAGC TCTGGTGGAGCATGGTCATGAGACTGGGATTTCATTCCACCTCTCTGTGACCTGGGTCAC CTTTCCCTGAGCCTCATCTTCCCCTTAGCTGTAAAACTGGGATGAGTCTGCTCACCTCAA AGGGCAGCTGTGGGCATTCAGGAGTGCCTGATGGTGGAAGCTGACTCTGTAGCCGACTTA TCTGTGACTGTCTCACTCTTCTCCCAGAGACTGTATGCTCCTTGAAGATGGAAGCTGTGT TGTGTGGGGCGGGGTGGGGAAGCATGATGCCAAAAGCCAACTCCTTATTCCCAGCCCAGA CACTCACTGCCTGGTTAAGAAAACAGCCAGAGAGGCCGGGCTCGGTGGCTCACGACTGTA ACCCCAGCAATTTGGGAGGCCAAGGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCA GCCTGGCCGACATGGTGAAACCCCGTCTTTACTAAAAATACCAAGCAGTTAGCCAGGCGT GGTGGCTTGCGCCTGTAGTCCCAGCACTAGGGAGGCTGAGGCGGGAGAATCGCTTGAACC TGGGAGGCGGAGGTTGCAGTGAGCTGAGATCGTGAGTCTGAACTCCAGCTTGGGCAACAG AGTGAGGCTCCATCTCAAAAAGAAGAAAAGAAAAGCAAATAAAGGAAAACACACCCAGAG CAGTGAGAGAAGTCTGTATACAAGACCCATTTGTGCAGTAGAGGCTGTGCAGGCAGGTAC CGGGAACAGGGCTCCACCTTTTAGAAGGTGGTCCTCTGGCCGGGAGCAGTGGCTCACGCC TGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCATGAGGTCAGGAGATCGAGAC CATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGTG TGGTGGCAGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAA CCTGGGAGGCGGAGCTTGCAGTGAGCCGATATCGCGCCATTGCCTCCAGACTGGGCGACA GAGCGAGACTCCACCTCAGAAAAAAAAAAAAAAAAAAAAAAGAAGGTGGCCCTCCATCCC CTGCCCTTCCCTGGCGATTGCCAGCCCAGTGCAGGGCCTCAAGTCTTCCATTTTGGAGAG GAAGCCTCTGGGACTCAAAGAGCACTCAGGTGCCGTCTCCACCGCAGCAGGGAGTTGTCG CCACTGTCCTTCCCCACATCTGTGGGTGGATCTGTCACCACCCACCCCACCTTCCCTCAG GCTCTAGCTGCCTCATTGTCTCCTCTCTGGTCTCACCATCCTCTCCTCAGCTGGCTTCTG CTCTCTGCTTCTTGGACTTGGCCAAGTGCATAGGGGATACTGGGGAGGCCTGCCCAGACT GCCTTAGCCCCTGCCTGGACCAAGGTCTGCCTTCAGAATCAGTCAGATAGGCCTGGGTTG CTTTTCTAGGCTGCCCTTTACTTGCTCTGTGAACTTAGGCCGATAAAGTTATCTTTCTGA GCCTCAGTTCCTTAACTGTGAAATAGGAGTGACAGTGCTGCCTTCTTCAGCTTCCTGTGA GGAATAAAAGGGTTTTGCATATGGAAGATACAGTGAGTTAGCCGGTGCCCCCAGGGGCTC ATATTTTAGGAAGTTGATTGGTATGGTGGACAGGCATGTAAATTAAAGTGATTGTGATCC AAAAGTCTGTCCCAGTTTCTCAGAGAGAATGACTAGTTCAGGATGGAGGAGGGATCAGAG GAGGTGACTTTGAGACACCAGTAGATGTTCTTCCAGTGGGATAAGGGATGGGAAGGCGTT CCAGGTAAAGAGATGCAAATAGTATGGAGAGGACAGTTAGCATTCTGGCCTGGTGGGTCT GGCAAGGAGATTGTGTGGGAAGAGAAGGGAGGATGTGATAGATAGGAAATGAAGCTAAAG GTTCTGTCAGTACCCGATGTTGGAGACCTCTAATACCCAGCTAAGAAATGTGGGCTTTAT CTTCCAGGAAAAGGGGACCACTAAGGAGTCCAAGCAGGCCAGCAGCTTGCTTCAGGTTTG AGGTTTGGAAAGATCATGAATGAGGCCGGGCATGGTACCTCACGCCTATAATCCCAGTAC TTTGGGAGGTCGAGGTGGGAGGATCACTTGAGCCCGGGAGTTTGAGACCAGCCTGGGCAA CATAGTGAGACCTTGTCTCTACAAGAAAAAAAAAAATTACAAATTAGCCAAGCGTGGTGG TACATGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGGGTCGCTTGAGCCTAGG AGGTGGAGGTTGCAGTGAGCCGTGTACGTGCTGCTGCACTACAGCCTGGGCAACAGAGTG AAACCCTGTCTCAAAAAAAAATAAATATATATATGTATATATATACACACACACATATTT ATTGATCACGAATGACTTGGAGAATGAGAGGAGGGGATGAGGGTGGGGACCGGAAGACCA GTGAAAAGTTGCTGTCTTTCCTAGGGAAAGGAGGAGGAGACACAGTTCCAGGCAAGCTGA GAGACTACTAGGGAGCATGGGGAGGAAGGAGGCAGAAGAAATTTCTTTTTTTTTTTTTTT TTTTTTTGAGACGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGA CTCACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTTTCCTGCCTCAGCCTCCCGAGTAG CTAGGACTACAAGCGCCCGCCACCACGCCTGTCTAATTTTTTGTATTTTTAGTAGAGACG GGGTTTCACCGTGGTCTCGATCTCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAAG TGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAGAAGAAATTTCTAATAACACTCA AGGACGCCAGCTCTGGAGTCTGACTAACTTGGTTCAGATCTTGGCCTTCTCTTCCAATCT TGAGTGAGATACTTCACCTTTCTGAGCCTCAGTTTTCTTCTCTGTAGAGTGGGATCATTG TGGCCAGCTTGTAGTGAAACGCTCCAGAATATTAGCCAAACACAACTAAGGAGATGTTGA CTGGGTTTGTTCCATCCATGATAACAGATTTTTTGGTTAATGCCCCATGACACCAACACT TCATATAGCCCTTATGTGTCTGACTCCATTCCGGGCTGTGCTCATGGCAGCCCAGCCATC AGCACCAACTGTGCTGACATAATTGTTTCCTGCTTTTTCTCCTGACTTCTTATTGTGAGT ACTTTTCATGCTAATACAGTCTCCCTCCCAGGCACAGCAGACTGCTACAGATTATTCTGA TGAACTGATGAGATGTTTGCCTTGGCATACAGCTGTCTATCTAAAACAAGGGTGCCTCTT TTTTTGGTGGAGGGACAGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGTGCAAA CTCGGCTTACCACAACCTCCACTTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCG AGTAGCTGGGATTACAGCACGCGTCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGA TGGGGTTCCTCCACGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCG CCTTGGCCTCCCAATCTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCACAAAGAT GCCTCTTATATCCCACATCCCTACCCCATCTAACTTTGCCTGCCTGACATCCTTTCTGGG ATGGCTCCCAAGCACTTCAGATTGAATGAAAACACCTAGCAACATGGAGCTTCACGTCTC TTCTCTCCTGTTTGTTCAACAGTGTTCTCTATCTCACTACATGGAAGTCTACCATCTACC TGGTCATTTAAGCCCAAGCCTGGGAGTCTTTGTGTTTGGCCAAGCTCATAGGGGGATCTT GGGCAGGCCTGCCAAGAATCCTCTGGACTTTTTTAGGATGAACAAATCAAGCCAAGTGCT GTGGCACGTGCCCATGATCCCAGGCTCTTGGGAAGCTGAGGTGGGAAGATCGCTTGAGTC CATGAGTTCGAGGCTGCAATAAGCTAATTGCACCACTGCACTCCAGCCTAGGTGACAGAG TGAGACCCCCTCTCTTAAAAAAATAAAATAAAAGGCCAGGCATGGTGGCTTACACCTATA ATCCCAGCACTTTGGGAGTCCAAGGCTAGAGAATCGCTTGAGCCCAGGAGTTCGGGACCA GCCTGGGCAACATGGCAAGACGTTGTTTCTGCAAAATATACAAAAATTAGCCGGGCGTGG TGGTGCACACCTGTAGTCCCAGCTATCCAGGATGGCTCAAGCCCGGGTGGTTGAGGCTGC AGTGAGCCATGACCATGCCACTGCACTCAAGTCTGGGCAGGACCCTGTCTCAAAAATAAA TACAAAGGATGAACAAATTATGAGAGTAAAAAAGGGTTAGTCTCCTTTATCCTTGCTACA CCTCCTCACCCAAAGCCAAGCAGTAGTGTAGCAGGATAAGCCGCAGACAAAACCCCCCAG ACACCCAGTTAAAGAAGGAAGGGCTTTATTCAGCTGGGAGCTTTGGCAAGATTCACGTCT CCAAAAACTGAGCTCCCCGAGTGAGCAGTTCCTGTCCCTTTTAAGGGCTTACAACTCTAA GGGGGTCTGCATGAAGAGGTCGTGATTGATTGAGCAAGCAGGGGATATGTGACTGGGGGC TGCATGCACTGGTTATCAGAACGGAACAGAACAGGACAGGGATTTTCACAGTGCTTTTCC ATACGATGTCTGGAATCTATAGATAACATAACCGGTTAGGTCAGGGGTCGATCTTTAACC AGACACAGGTCGCGGCGCCAGGCTGTCTGCCTGTGGATTTCATTTCTGCCTTTTAGTTTT TACTTCTTTGGAGGCAGAAATTGGGCATAAGACAATATGAGGGGTGGTCTCCTCCCTTAG TAGTAAAGCACTATAAATATTTGTGGATTTACAACCATTTCATTCAGTCTTGATGACAGC CCTGAGAAGTAGTCATTGCATCCCCTTTTATAGATGAGGATACAGTTCAGAGAGGTTAAG GCAACTGGCCAGCCACAAGCTCTGGAAGGTGAACCCAGTTCCCTCTAATCCCAAAGAATG TGCACTTTTTAGTGTGGGACAAGGGGTCTCAAAAGACAGGTGGGAGGATTCTCAGCCCTG GGAGAATAAAAGTTGGGTGAAGTTCAGAACTGCCACCTCATCAGTCAGAACTGGGCCAGT GACAACCTGCAGAAGCTCAGCCTGCAAAGGCTTATCAGGATTCTAGACCTTTGGTTACTT TCCCATCTTTAGTATTTAGTTCTCCTTCCCCAGGATAATCAGCAGAAAAGTGCCTGGCCT TGTGTCCATATACCATGGAGGGGAGAGCTAGAGAGGCGAGGTTCTCGGGAACCACTAGAA GGAAGGAATGAGGGGGCTGCTGGTTAGGCCCAGAGCTGAGACCGAGAAGGGCTCTTGGAG TTCTCCTTCCCTTCGTAACATTAGGTAGAGGCTTAGACAACTTGATTGTTTTTCATGACC TTAAAGACTGTGGCTCCGGCCGGGCATGGTGGCTCACAGCTGTTGTAATCCCAGCACTTT GGGAGGCTGAGGCGGGTAGATCGCTTGAGCCCAGGAGTTCTAGACCAGCCTGGGCAACTT GGCAAAACCCTGTCTCTACAAAATATATAAAAATTAGCTGGACACTGTGATGCGCACTTG TAGTCCCAGCTATTCTAGAGGCTGAGGTGGGAGGATCACCTGAGCTCAAGAGGTCAAACC TGCAATGAGCCGTGATTGTGCCACTGCACTTGAGCCTGGGCAACAGAGAGTGAGATGCTG TCTCAAAAAAACAAACAAACAAACAAACAAAAACAAGTACTTGATGACTCCATTGGGGTC AATTATGAAGAGACCTCTTAGTGCAAGACCAGGACCTTCTAACAGCACACCGAAGTCTCG AGAAATTCGCTTAGTTAAATCTGACAAGGGTGCGATGTTTATGTGGCCCAAAGCACCATT CTTTCTTGGTGTATTTATCCAGGCAAGACGGCTAAAGTGGGAATCCACTGAGACTGCAAC AACTTCAAAGTTCACATCGTGAAATTCCTTAGCTTTGTCACTAGAAGCAACAATTTCTGT AGGACACACAAAGGTGAAATCCAAAGGATAGGGCTGGGCGCGGTGGCTCACACCTGTAAT CCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGC CTCACCAACATGGTGAAATCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTCGTG GCAGGCGCCTGTAATTCCAGGTACTCAGGAGGCTGAGGCAGGAGAATTGGCTTGAACCCA GGAGGGGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGTGACACAG CAAGACTCCGTCTCGGAAAAAAAAAAAAAAAGAAAGAAATCCAAAGGATAGAAGAAAAGC ACCAAATATTTCCCCTCAAAGTCATCAAGGCTTAGGTCTTTGAACTCTCCATTGACCACG GCTGTACCCTTAAAATAGGGCGCATGCTGGGTGACATCAGGTGCATGGTATGAGGAACTG GTACCAGAATTTTGCTTGACCGGAACCAGACCACAATATGTTTGTCAAACTTGTTCTTCC AGAAGCAGCAGGCCTGAGGGCTGCAGTGGCAGAAATGCCCCCAAGGAATGGCACTCACAT GCCGGGCAACTGATGCTCAGAGTAACCTTCCCACAGCAGCCGCGATCTTCAGTGCATGTG TGTTTTTGTTTTTTTGAGACAGTGTCTGTCTCTTTCGCCCAGGCTAAAGTACAGTGGCAC AATCTCAGCTCAATTTAGCCTCAGCCTCCCAGGCTCACGCCATCCTCCCACCTCAGCCTC CTGAGTAGCCAGGACTTCAGGCGTGCACCACCATGCCCGGCTAATTTTTGTAATTTTTTG GATAGAAATGGGGTTTCGCCATGTTGCCCACGCTGGTCTTGAACTCCTGGGCTCAAGCGA TCCTCCTGCCTCGACTTCCCAAAGTGCTAGGATTACAGGTGTGGTGGCACCTTGTCTCTA AAAAAAATCAATCAATTAAATAAGAAAAGAAAATAGCTCTTCTCCCCCTCTGATTATAAC AACACATTACCAAAGTTACTGGTGCTTACATGGGGTTGAATGGAGTTATGATGGATATTT CATTTAATGTTGTTCTTCAATGTTTTAATTTTTTACAACAGACTTAAAAATTTTTTAAAT ACATGTGGCCAGGCACGATGGCTCACGCCTGTAATCCCGCACTTTGGGAGGCCAAGGTGG GTGGATCATCTGAGGTCAGGAGTTCAAGACCAGCGGGACCAACATGGAGAAACCCCATCT CTACTAAAAATACAAAATAAGCCGGGCGTGGTGGCACATGCCTGTAATCCTAGCTACTCC AGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGTAGAGGTTGTGGTGAGCCGAGAT TGCGCCATGGCACTCCAGCCTGGGCAATAAGAACAAAACTCTGCTTCAAAAAAAAAAAAA AAAAAACATGTAATCGGCTGTACGCAGTGGCTCACGCCTGTAATCCCAGGACTTCGGGAG GCTGAGGCAGGTGGATTACTTGAGATTAGGAGTTTGGGACCAGCCTGGCCAACATGGTGA AACCCCGTCTCTACTAAAAATACAAAATTTGGGCTGGGCACAGTGGCTCACGCCTATAAT TCCAGCACTTTGGGAGGCCAAGGCGGGGTGGATCACTGAGATCAGGAGTTCGAGACCAGC CTGGCCAAACTGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTG GTGGGTGCCTGTAATCCCAGCTACTCGAGAGGCTGAGGCAGGAGAATCACTTGAACCCAG GAGGCAGAGGTTGCATGAGCCGAGATCGCACCATTGCACTCTAGCCTGGGTGACAGAACG AGACTCCATTTCAAAAAAACAAAAACAAAACAAAACTTAGCAGGGCATGGTGATGCACAC CTGTAATCTCAGCTACTCGGAAGGCTGAGGCACAAGAATTGCTTCAACCCGGGAGGTGGA GGTTGCAGTGAGCTGAGATCATGCCTGTGCGCTCCAGCCTGGCGACAGAGTGAGACTCCG TCTCAAAAAACAGAAAAATACATGTAATGCTCCTTGTTAAACATCTTAGATAATATAGGA AGATAAAACGAAACAAGTAATGATTATCTATAATACCATTTTCCGAGGTTACCATTGTTA ATATGGGATATATTTTCTTCCCCACATTTTTCTCACATATTTTTTGTGTATGCATTTTTT TTCCAAAAAAAAAAAAAATGGATGATAGGCTGTTTTTCTTCCTTTTTTTTTTTTTTTTTT TTGGTTGGGGGGTGGAGTTTCACTACTCTTTCTCCCAGGCTGGAGTGCTGAGTGCAATGG CATGATCTTGGCTCACCGCAACCTCCACCTCCTAGGTTCAAGCAATTCTCCTGCCTCAGC CTCCCAAGTAGCTGGGATTACAGTCGCACACCACCATGCCTGGCTAATTTTTGTATTTTT TTTTTTTTTTTTGGTGGCGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCT GACCTCAAGTGATCCACCCACCTTGGCCTCCGAAAGTGCCAAAGTACTGGGATTACAGGC GTGAGCCACCGCGCCCAGGCTTTTTTTTTTTTTTTTTTTTTGAGACAGTCTGGCTCTGTT GCCCAGGCTGGAGTGCAGTGGCTCGATCTTGGCTCACCACAACCTCCACCTCGCGGGTTC AAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCATCACTGTGC CTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTGCCATGTTGGCCAGGCTGGTTT GGAACTCCTGATCTCAGGTAATCCGCCCGCCCCGGCCTCCCACAGTGTTGGGATTACAGA TGTGAGCCACCACACCTGGCCGTCTGTTTTTCATTCTGCTTGTTTTACTTGGCAATGGGG AACATCTTTCTATTCAATAGATTGATCTCTGAAAACATCACTTTTGATGGCTTCATACTG TTCTATCATGAATATACCACATATTTAGTTCACTACTATTGAACATTCGGGTTCTGTTTT TGTTGTTTTTAAAATGTTATGAAGGATACAGTAGAGAATATTTGTGTAATTAATCTGTGG GTGCATCCATTATTCTGTTCTTGGGATACATTTTGAGAAGTGGAATTGTTGGGCAATTCC TCTTAACGTATTTCTAGAGTGTTTGATAAATATTGTCTGATTGGCCCAGGAAAATGTTTG CCATTTCTCATATGTAGTATTTGACTGACTTTCAGGACAGGAAGATGTCACCCAAGCGCA TAGCTAAAAGAAGGTCCCCCCCAGCAGATGCCATCCCCAAAAGCAAGAAGGTGAAGGGTA AGTTGGCCTTGGCCTCTTTGTGGGTACAGGTGGCCCCTTGAAACCCTAAGAACCCGGGAC TGGGCTCCTTTCTTCCTGAGGCTTGAAGCTGAAGGGTGTGGATGTGCAGAGACCCCACCC AGCTGGAAGGTTTCCTGTAGCTCATTGAATCCTACCCTCTGGGAATCACAAAGTGGGCAG AAACTCCTCTCAAAGCACTCAGGCAGCACTGGCACAAAAAAAAAAAAAAAAAAACTAGAC CCTAGGGCTTCACCCCAGGCAGTGATGCATTATGGTTAGGACCACTGACTTTCCGACATG GGTTCAAGTCCTTGCTCTGCCACTTTCTAGCTGCTGGGCAAGTCACTTAATCCCGCAGTT TGGATTATCAACTTCTTAAAATGGCGGCAGCCAGAGCAGCGTCACCCTCTCTGGGCTGTG TGAGGATGAGATGAGATAATGGCCTGGCAGCATTTGAGGGAGGTGGCTGTGGTTTCCTCT GTCCTGGGACCCCGGAGGGGGACAGGGAGGAGAGAAAAGCCAGCACCAAACTGGGAGGGG AAGTGTGGACCCACGCTCAGACAGTGTCTGTCTTTTGCAGACACGAGGGCCGCTGCCTCC CGCCGCGTTCCTGGCGCCCGCTCCTGCCAAGGTGCCTGCGGGCCGAGCCCTCCTGACCAG AAAACCCGACCAGGTGGCTCCGCGCCCGGGGCGCCCTCTGTGCTGCCAGCGCGGGCTCCT CAGCGGTGGCCACATCCTCGGGGGAGGGGCTGGGCGCCATTGGCTGCCCGGGGCTGCGGG TTGGGGGGCCGCCTTTGGCCCACAGAGAGCCCCGGGCGCGCACCTCCCGCAAATGCCGCT GTCCGCTCTTCCTCCCGCCCCTCCTGCCTCTCCACTGGATGGTGGAGGGAAGAGTCCGTT TCTGCAGTGGATTTGCCCGGGAGCTGAACTTATTCACTGGCGGACGGCTTGGGCATGGAG GAGGGCTTGGATGGAGACTGGGGATTGTTCTCTGACCCACGTAGTCTCCCTTGCTTTCGG TGCAGATTCTGCTATTATAATTAGCTTTCTGCGGGGCAAGGTGGCTCACGCCTGTCAGAA GATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTA GCCTTGCGCGGTGGCGCGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGAGGAAT CGCTTGAACCCGGGAGGCAGAGGTTGCAATTAGCCAAGATCCACCACTGCACTCCAGACT GGCGACAAAGGGAGACTCCGTCTCAAAATAACAATAACAATAATTAGCTTTCTTTTCTTT TTCTTTTTTTTTTTTTTTTTGAGATCAAGTATCACTCTGTCGCCCAGACTGGAGGCGGCA GTGGCACGATCTTGGCTCACTGCCACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCT CAGCCTCCTGAGTAGCTGAGATTACAGGCTACTGTTGGCAAGGCTGGTCTCTTAACTCCT GACCTCAAGTGATCCGCCCGCCTTGGCCTCCCACAGTGCTAGGATTACAGGTGTGAGCCA CCGCACCCAGCCCTTCTTGCCCTCTCCACCAAGATTCATTTCACAGTATCCAGTGTCTCC TTGTTTCCCTTTCTCCCCTTTCACGTGAATAATGTGCTCAGTTCTTAATCTCCACAAAAA TCCTGTGAGAGAGGTACTTTTGTTGTCCCCATTTCACAGATGACAAAACTTAGAAAGTTC ATACTAACAGTCTGTGGCAGAGCAGGGGCTTCTGCACAGGTTTGTCTGATCCCAGAGCCT GTGACCTCTCCTCGCTGTCGTCATCCTCTACACTCAGGGTCTATCTTCTTCACCCTTCAG TCTCACACAGGTCCCACAGCACAGAACCCGGCTTGGTGCTGACACTAGGCCAGGGCGACG TGGGCCAGCTGGGGCTGGGTGAGAATGTGATGGAGAGGAAGAAGCCGGCCCTGGTATCCA TTCCGGAGGATGTTGTGCAGGCTGAGGCTGGGGGCATGCACACCGTGTGTCTAAGCAAAA GTGGCCAGGTAGGTGTTGGGGACTGGCACAGGGTTGGACAAGGCCTGGGGTTGGGTGGCT TGGGGCAGGGCTTTTGAACCACGCATGTTCACTGTGGAAATGGAGCTGGCTAGTCAAGTG GGGAGTGGCCTACATGAGAATGGACTGCGAGGCCAGACGTTGCATTAATGAGGGCATCCT GGGCACAGGTCTATTCCTTCGGCTGCAATGATGAGGGTGCCCTGGGAAGGGACACATCAG TGGAGGGCTCGGAGATGGTCCCTGGGAAAGTGGAGCTGCAAGAGAAGGTGGTACAGGTGT CAGCAGGAGACAGTCACACAGCAGCCCTCACCGATGATGGCCGTGTCTTCCTCTGGGGCT CCTTCCGGGTAAGGCTGGGTCTGAAAGTCTGCATGGTCCCTGAAAGACAGAATTAATTGG CGGGGCCCCAAAGATAATCCACTTCCATGCCCCCATGGTACTTACTGGTGGGGAGATGAA AGCCCACAGGTAGAGCTGAGGCCCAGACCCAGGACTCTAGCTTCCTCATGTGGGCCTGTC CACGCCACTGGCTGCTTCCTTGAATCCGATGTCATCAAGTGTCTGTCCTGGGAAGTGAGT GGGTCAAGGATGTCCCTGGGTTGAGGCTGATCCAGGAGGCCTGCTGTCTTCACCCATCTC CCTGACTTCTGTCTCCCCCTCACCTTGCCAGCACTGCCTCTTCCACACTTCCCAGAGGCT TGGATGGGGCAAGGAGGTGTGGAGGCAGGGATTGTCGCATCTCAGAGTTTCCAAGGTACA GAGGAGTGTAGTTGAAAAAACAGATTGTGGGTTTTTGTTGTTGTTGTTGTTGTTGTTTTT GTATTGTTTTGAGATGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATAGCGCAATC TTGGCTCACTGCAACCTCTGCCTCCCAAGTTTAAGTGATTCTCCTGCCTCAGCCTCCCAA GTAGCTGGGATTACAGGCATGCGCCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGA CGGGGTTTCCCCTGTTGGTCAGGCTGGTCTCGAACTCCCGACCCCAGGTGATCCACCCGC CTCAGCCTCCCAAAGTGCTAGGATTACAGGCGTGGGCCACCACACCCGGCCTGATGGGTG TTTCCTTATCACATCTATTTTGAAATTTTCATGGAGAATTTCAAACACATGAAAGTAATC AGAATTGGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGATGCCAAGAT GGGCAGATCACGACGTCAGGAGATCGAGACCATACTGGCTAACATGGTGAAACCCCGTCT CTACTAAAAATACAAAAAATTAGCCAAGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACT CGGGAGGCTGAGGCAGGAGAATGGCTTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAG ATCGCGCCACTGCACTCCAGCCTAGGGGACAGAGCGAGACTCCATCTCAAAAAAAAAAAA AGAAGTCCGGGCGCAGTAGCTCATGCTTGTAATCCCAGCACTTTGGGAGGCCGAAGCAGG CTGATCACCTGAGGGGTCGGGAGTTCGAGACCGGCCTGACCAACATGGAGAAACCCTGTC TCTATTAAAATTACAAAATTAGCTGGACATGGTGGTGCATGCCTGTAATCCCAGCTACTC GGGAGGCTGAGGCAGGAGAATTGTTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGA TCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCAAAAAAAAAAAA AAAAAAAAAAAAAGGAAGTAATCAGAATATCAGAATTATATTTTTTTCTTTTCTTTTCTT TTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAG AGTCTTGCTCTATCACCCAGGTTGGAGTGCAATGACACAATCTCGGCTCAGTGCAACCTC TGCCTCTCGGGCTCAAGCAATTCTCCTTCCTCAGCCTCCCGAGTAGCTGGGATTACAGGC ATGCGCCACCACACCTGGTTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTT GGCCAGGCTGGTTGTGAATTTCTGATCTCAGGTGATCCGCCCGTCTGGGCCTCCCAGAGT GCTGGATTGCAGGCTTGAGCCGCCACGTCTGGCCTCTTTTCTTTTTTCTTTGTTTTGAGA CGGAGTCTCGCTTTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAG CTCTGCCTCCCTGATTCACGCCATTCTCCTGCCTCTGTCTCCCGAGTAGCTGGGACTACA GGCGCCCGCTACAACGCCCGGCTAATTTTTTGTATTTTTTGGTAGAGACGGCATTTCACC GTGTTAGCCGGAATGGTCTCGATCTCCTGACCTCGTGATCGCCCGCCTTGGCCTCCCAAA GTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTCTTTTCTTTTTTAATTAGAGAC GAGATCCTGCTCTGTCACCCAGGCCAGAGTGCAATGGCATCGTCTTAGCTCATTACAGCC TCAACTTCCTGGGCTCAGGTGATTTCTTCCACCTCAGCCTCGCAAGTAGCTGGTACTAGA GGCTTGTGCCACCACGCCCAGCTAATTTTTGTATTTTTTGTAGGGACGGGGTTTCACCGT GTTGCCCAAGCTGGTCCTGAGCTCAAGCGATCTGCCCACCTGGGCCTACCAAAGTGCTAG GATTACTGGCATGAATTACCATGCCTGGCCCAGAATAGTATATTGAGTGCCCATTTACTT GCCACACAGTTTCAATGATTATCAGCTTGTGGCCAGACTTGTTTATCTCTATTTGCATCC GCTCTCTGACTCCTTGATTATTTTAATGCAAGTCGCAGACCATAAATGATTTCATTCATA AGTATTTGAGTATGTGGCCTGGCTCCTGCCCACTTCTCCATCCCCATCTGGTGCCACTGC CCTTCTGGATTTCACTGGCACGGGGCAGGCAGGACTGGCTGATAAGTGCCCTGTCCCTCC CTTCTAGGACAATAACGGTGTGATTGGACTGTTGGAGCCCATGAAGAAGAGCATGGTGCC TGTGCAGGTGCAGCTGGATGTGCCTGTGGTAAAGGTGGCCTCAGGTGGGTCTGGGGGCAC TTGCTCAGGGCAGGAGTTGGAGGACCTTGTTCTGGGGCTGGCCTAGCCTTGGGCCTTACA GTTGTGGCCTGCATCCCTTACCTTTTCATCCTTAGGAAACGACCACTTGGTGATGCTGAC AGCTGATGGTGACCTCTACACCTTGGGCTGCGGGGAACAGGGCCAGCTAGGCCGTGTGCC TGAGTTATTTGCCAACCGTGGTGGCCGGCAAGGCCTCGGTAAGTGGCCTTGGTACCTCCA GCAGGGCAAATTGGCAGGCCACCCCCACAGTGAAGGCCAAAGGCAGGAAGGATTTGCTGT GGTCAGGCTTGCATCAGATGGGCTTGTGGTGTTGGTTAGGACTTTGGAGACAGACTGCTC TGGTAGTTTTGCCACCTACTGTCTATGGGACTCTGAACATAGTTTCTTCATCACTAAGTC TACCTACCTGTAAACCTACTTCATTAGGTTGCTGTGAAGTTAAATGAGTTAATGAGAAGA ATATCAGGCAGATGGTAAGTTCCACGTAAATGATACCCGTAATGACTGTGGGAATCTGAG CAAGGCACTTGTATTCTCTTGATCTCAGTTTCCTTTTCTATAAAATAGGGATAAGAGTCC CTACTTAGCCTCTCAAGGGCTTTTATAATGGAGGAGAATTAAACTCGGGGCAGAGAGAAG CCATGTGTGTCTGTCTGTCACTGACCGTGGCTTTCCCTTTGCCTGCAGAACGACTCCTGG TCCCCAAGTGTGTGATGCTGAAATCCAGGGGAAGCCGGGGCCACGTGAGATTCCAGGATG CCTTTTGTGGTGCCTATTTCACCTTTGCCATCTCCCATGAGGGCCACGTGTACGGCTTCG GCCTCTCCAACTACCATCAGCTTGGTGAGCCCCGAGCCCAGCTTCAGGCATGACCCAGTG GCCTGCGTTCCTGTCCTGGCTCTGCCACTCATTCATTGTGCATCCTTTGCGGGGTCGTCT AACCCCTCCAAGCCAGTTTTGTCATCTGTAAAGTGAGAATGTCCATATCCTGATGGGAGG TGGCCTCACTGTGGGAGGAGATTGAGAAGGGCAGCTCTCAGAACACCTTCACCCCTGATG GCTCCGGCCTTTCCCCCAGGAACTCCGGGCACAGAATCTTGCTTCATACCCCAGAACCTA ACATCCTTCAAGAATTCCACCAAGTCCTGGGTGGGCTTCTCTGGTGGCCAGCACCATACA GTCTGCATGGATTCGGAAGGTAGGGCCTTTACGTCCTTCTCTAGTTTGGGGGTGGAGTGT TCCCTGGCCTAGGCCTAGCCAGATTCCTGAGACCATGGTCCTTGGAGCCTGGGTCTGTTC CATGGGTTGTACCATACATGGGTCCATGAGAGTCACTCTCATCCTCCTAGAGTCCTGGTG TTCTTCCAAGTGTGAGTTCAATGGGGGCCCATGTAGATTCTCCTAGGCCTCCTCCAAAAC TGGGAAGAGACACTGCAGATCTCCTTCTGATCGCTCTGGGAGCAGGGACACACTCCCATG GACAGGTGGACTCACCTAGCCTGCCACCCATTTTGCCTGTAGCACGCCCTCTGCTATTGC TCATCTCTCTCCCTCCTCCCATAGGAAAAGCATACAGCCTGGGCCGGGCTGAGTATGGGC GGCTGGGCCTTGGAGAGGGTGCTGAGGAGAAGAGCATACCCACCCTCATCTCCAGGCTGC CTGCTGTCTCCTCGGTGGCTTGTGGGGCCTCTGTGGGGTATGCTGTGACCAAGGATGGTG AGTGGGGCTGCCTACACTCTGTCTAGTTGGGACCTGGGGGTCATGGTTCTTACCCAATTC CCCAATAGGCTGTGATGTCCACTCTCGGGGGAGCCGAGGTACAGAGAGCAGTGTTTGTGA TGGCACTTTGTTCCTGCTTCTCAGAAGCTCTGGCATTGATGAATATGAAATGAGTACACA AATTATTTTAGTAAAGGTGACTTATTATGCAGAGGAGAGAAATAGCAAAGAGTGAGATAT CACTGAGGCCTAAGGAGGCAATGGGACTGGAACCCAAGTCTCCAGACTCCTAACCCAGGC TGCTCTCTCCCCTCAGGGTGACCCCTTCATATATCACCTTGTATGTTCCCGCTTTCCAGG GACTTTTACTTAGAATCTAAATCAAGAAAAAAAAAGGCTTAGTAGTCAGAGTTGTAGCAA CTATAGCAGAGGAGGGTGTGAACAAGTGACCACCAAAGCCTGAGTGGGTGAGGGGGATAG CCATGGAGGTCCTGTAGAAGCCTGGAGCTGGCAGAGGTGCTTGACCTGAGGTTATCTGGG AAGACTTCCTCAGGAAGTGGGGCTTGCACTGTACCTTGAAGGTTCCATTCCTTGTGAAAA GCAAAGAATGCCATTCCAGGCAGAGGAACATCAGGGCAGTCTCAAAGGTGGCTGGTCCTG GGAACAGAGGGTGGGGTAGGACCTTGAATGCCACGCCTAGGAGCAGCCTTTGGCAGTGTG TAGGGACTGTGCTCTCTGGTTTACAGAGTTCTTTTTTATCCATCATCTCCTTGGGTTCTC CCAACTTCCCTGAACTCCCAGAGTCTGGTACCTTGCCAAGCTGCTATTGGCCAAGGCCAC AGTCCACGCCCATGTCCCAGGTTTCTCCTGCTACAGAAAGGTGGGCTGGGGATCCTGGAG ACAGCTGTACCCATTTCTCTCTCTTGCAGGTCGTGTTTTCGCCTGGGGCATGGGCACCAA CTACCAGCTGGGCACAGGGCAGGATGAGGACGCCTGGAGCCCTGTGGAGATGATGGGCAA ACAGCTGGAGAACCGTGTGGTCTTATCTGTGTCCAGCGGGGGCCAGCATACAGTCTTATT AGTCAAGGACAAAGAACAGAGCTGATGAAGCCTCTGAGGGCCTGGCTTCTGTCCTGCACA ACCTCCCTCACAGAACAGGGAAGCAGTGACAGCTGCAGATGGCAGCGGGCCTCTCCCCAG CCCTGAGCACTGTGTCAGTTCCTGCCTTTTCTCATCAGCAGAACAGAATCCTTTTCCTCT TTTCCTTCCTCCTCTTTGGAATTTTCCTGGGACCTACAGAATAAAGGGGGGGATGGACAG GGGGTTTTCAAAAGGAACATGGCTCACTCAGAGCTATATGGTTAGACGTTTCTCCCCTTT TCCCTACCTTCCATGGTCCTGGTTGGCCCTGGCTTTGCCTACTAGAAAACCAAAACTTCC CCCCTGGGGTTTTGTGCCCACTCTCTGAGAAGTTGGGGCTCCATCAAGCCCCATTCTAGT CATGTGCCCCTTTCCTGTCCCTAACAGTCCACAGGCAAACAAATGGTACAGTCATAAGAG CCATCTGTCACGGACCCACGCCCAGAGGAACGTGCAGAAAAAAGCAGAGCTACATGGCTG TGGGCAACTATAAGCCAAATATTTGGCTCAGAACAGGTGTCCATGGGACAAAAAAGAACG ATCCTCCACTTGACCAAGAAAAAAGTGATTCTCCCAGAAGCACAAAGCATACTCTTGCCC CTCAGGTGTTGCTTGTGTACATCGTACCCATCCATTCGGCTTCACCTGCAGCCAACGGCC TGGAATCGCAAAGAGACACCACTCTGGGCAGAGCAGAGCAGGGTATGGGGTGGGGAGAGA GGGTGGAGGGTTTTATAAACAAACTTAACAGCAATATTGAAAGGAGGTGGGGGATTGAGG GAGGGACAGAGTGTTGGAGGGCCAGAGACTAGTCCTGAGATGGAAACAGCAACTTGTACA GTGGCTGAGAAAATAGGATATAGTTTTGATTTTTTTAATTGTAAAATATTTTGGAGGGAG AACAAAATCTTTTAACATTTTGAATAAATTTAGAGTTTTATAAAATAGGCCACTTGTTTT CTACACATTCCCTGCTTTTTAAGGGAGCACATATTATGTGCCAGGCACTGCTGGGAAAGA CAGAATAAACTATAAACCTGGTGTTGAGGCTACAACTTAAGTGATGTCAAGATGTCCTGA GGTGCCAACCAGCTGTCAGTGTGACTGTAACAAAGGCTTCAAATCTGTCAAGAAGTAAGG AAAAGTTTTGTTTGAATTTTGTTTGGGTATTTCTGTTTTGGGAGTCACTGGATTATTTTT AAATGCTGCATAGTACAATAGAGGCAGGGTGGATCTTTTAATACCAAACCAAAAAAAA bcftools-1.21/test/csq/ENST00000373833/ENST00000373833.fa.fai000066400000000000000000000000211467060157400215360ustar00rootroot000000000000001 33358 23 60 61 bcftools-1.21/test/csq/ENST00000373833/ENST00000373833.gff000066400000000000000000000106771467060157400211760ustar00rootroot000000000000001 ensembl_havana gene 1 33358 . + . ID=gene:ENSG00000180198;Name=RCC1;biotype=protein_coding;description=regulator of chromosome condensation 1 [Source:HGNC Symbol%3BAcc:1913];gene_id=ENSG00000180198;logic_name=ensembl_havana_gene;version=11 1 ensembl_havana transcript 115 33358 . + . ID=transcript:ENST00000373833;Parent=gene:ENSG00000180198;Name=RCC1-003;biotype=protein_coding;ccdsid=CCDS323.1;havana_transcript=OTTHUMT00000010323;havana_version=3;tag=basic;transcript_id=ENST00000373833;version=6 1 ensembl_havana exon 115 142 . + . Parent=transcript:ENST00000373833;Name=ENSE00001935788;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001935788;rank=1;version=1 1 ensembl_havana five_prime_UTR 115 142 . + . Parent=transcript:ENST00000373833 1 ensembl_havana exon 2186 2218 . + . Parent=transcript:ENST00000373833;Name=ENSE00003478538;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003478538;rank=2;version=1 1 ensembl_havana five_prime_UTR 2186 2218 . + . Parent=transcript:ENST00000373833 1 ensembl_havana exon 2888 2959 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273591;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001273591;rank=3;version=1 1 ensembl_havana five_prime_UTR 2888 2959 . + . Parent=transcript:ENST00000373833 1 ensembl_havana exon 10783 10925 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273585;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001273585;rank=4;version=1 1 ensembl_havana five_prime_UTR 10783 10925 . + . Parent=transcript:ENST00000373833 1 ensembl_havana five_prime_UTR 23916 23924 . + . Parent=transcript:ENST00000373833 1 ensembl_havana exon 23916 23997 . + . Parent=transcript:ENST00000373833;Name=ENSE00003621347;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003621347;rank=5;version=1 1 ensembl_havana CDS 23925 23997 . + 0 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 25861 26048 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273582;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001273582;rank=6;version=1 1 ensembl_havana CDS 25861 26048 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 26229 26408 . + . Parent=transcript:ENST00000373833;Name=ENSE00003695605;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003695605;rank=7;version=1 1 ensembl_havana CDS 26229 26408 . + 0 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 29108 29204 . + . Parent=transcript:ENST00000373833;Name=ENSE00003696436;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003696436;rank=8;version=1 1 ensembl_havana CDS 29108 29204 . + 0 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 29316 29438 . + . Parent=transcript:ENST00000373833;Name=ENSE00003700481;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003700481;rank=9;version=1 1 ensembl_havana CDS 29316 29438 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 29929 30084 . + . Parent=transcript:ENST00000373833;Name=ENSE00003514701;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003514701;rank=10;version=1 1 ensembl_havana CDS 29929 30084 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 30320 30439 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273554;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001273554;rank=11;version=1 1 ensembl_havana CDS 30320 30439 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 30805 30957 . + . Parent=transcript:ENST00000373833;Name=ENSE00003467600;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003467600;rank=12;version=1 1 ensembl_havana CDS 30805 30957 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana CDS 31890 32065 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 1 ensembl_havana exon 31890 33358 . + . Parent=transcript:ENST00000373833;Name=ENSE00001828138;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001828138;rank=13;version=2 1 ensembl_havana three_prime_UTR 32066 33358 . + . Parent=transcript:ENST00000373833 bcftools-1.21/test/csq/ENST00000373833/boundary-insertion.txt000066400000000000000000000000351467060157400232450ustar00rootroot0000000000000033358 A ATT . 33358 A ATT . bcftools-1.21/test/csq/ENST00000373833/boundary-insertion.txt-l000066400000000000000000000000351467060157400234760ustar00rootroot0000000000000033358 A ATT . 33358 A ATT . bcftools-1.21/test/csq/ENST00000373833/boundary-insertion.vcf000066400000000000000000000004501467060157400232050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 33358 . A ATT . . EXP=.;type=ENST00000373833:28865812-A-ATT just after exon bcftools-1.21/test/csq/ENST00000375992/000077500000000000000000000000001467060157400166635ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000375992/ENST00000375992.fa000066400000000000000000000151501467060157400210310ustar00rootroot00000000000000>X X:51232843-51239468 TACAAGTAAACTCTGAAGAATACTTTTTTCAATTTTTATTATGGAAAATTTCAAACATAT ACAAAAGTATAGAGAATAGTATAATGAACTCTCAAACATCCATCACACAGCTTCAGCAAT TACCAATTTATGGCCAATCTTGTTTCATCTATGTACTCAATTACCCCACACTCAGATGAT TTTGAAGCGAATACCAGTAACATATCATTTCACCTGTACATTTTTCAGTATACTTCTCTA AAAGATAATCATTTTTTAAAACAACATAACCACAGTACCATATCACATCTTAAAAAACAA TAAATCAAGAAGTTATATTTTTATTTCAAATTATGTAACAACTGGGGACACAATCAATAC ATTTCACTGGTATCATGAGGAAGAGTGTCACACTAAAATGGAGTCCAAGCTTTTATCGAT GCAATTGCTTTATAATATAAAAGAAAAAATCAAACAAACTAGCATATTAGAACCACTTTT GGTAATTTGTAAGGAGCTGAAGACTGCTGATATCACACATCCCATGGCAAACTCCGTAAG ATTTCTTCTAAACATCTTTGTTATTTTCTTAAAATTGTTCTGGAGGCAGCTGATGCAAGT CCTCTTTTTTAAAAAAACCTTCACTTTGTGTTCCCCTCTAATAGCAGCCTCTTTCCTAAA TGCCTTTTCTAAATGACAACAATTTTGCCCTCTCTCAGCCCTCTGCATTCTCATATGCAG AAACCAGGTAGGATGAGGAGCTAGCTGTGTGTACTGGAAAAGGGATGAAAACTACAGCCA AATGGATCAGTGAGAGAGGCAAAAGAAATCTAGACAAACTAAATGGCATAATTAAGTTTG GAAACTGCCTATGATATAGCCTGTTGGCTCTGGCATCAAATAATACAGTATGTTAAATCT GTAAAATGAGGAAACAGTGTTTCCTCAAAGAGATGTTAAGATGACATGTAAGAAGTGGTT AGGGCAGGCATTGCAAAAAAATGTCTTATATATCATTTTAAAATTTATTTTTATAAAAAC TCACAACATTATTTTGCGTCCACTGTATTTATTTTTACAATTACCTTTATAGCAAGTGAT AGTTTTTGAATAAAATTTAAGCAAATCATCAACAGTACAAAAACACTAGAGTTGTTACAC GAAGGACTGATTCTACAAAACATTACCCTAGGTGATGGCATAATCTTAAAACTGTGCAGC TACTGTGTGGTATGACATAGAAATAGGAGTAATAATTCTTGTCCTCAAACATCTTACAAC TGTCTTGAAATATTTCTGAAACACCTGATACACAAAAGCCACACACATGGTGCCTAGATA GCATATACTCTACTAGCACCAGATTGGAAGGGGAATGTTTTGCCACACGGTGATTACAAA ATATTAATTGAATCAAAGAACCTTCAGTGATGCCAACCATATTTCAAGTAGTGTCTCAGA TGCAGAATATGCAAAGAGTAAGGAAAAATAGTCTTTGCTCTCAAAGACATCATAGTCTAA TGAAGGCAGACACATCAAAAAAGCACAACAAAAGGCTATAGGTGCTGAATTAAGAGTCTA TTCACGTATAAGAGTACAACAACCAGAGCAAGAGTCAGTGGTATAGACAGGGAAGGAGTG TCCCAAGATGCAGGAAGAAACCAGATGAGCTGTCTTCTTGGGAACACAGAAGTGCTCACC TGTACTTGACAATTCCACTGATCACTGGGTTCACATCAATGTTTCTTTCAGCACAATACT GAACATCTTTGCTGTTCATCTGGAAAAACAAACCAACACACAATTAGCAGGCTTATGTTA ATAATTCCTCCAACTGACAAATGTACCAAGAGCTTATTATGTACATCAATCACTTTGCAT CAAGCACTTCACTTCCACAGAATTATCTAATGCAGATGCAATCAATGAGTCTGGATCAGC AACTGAGGGGTTATAAGCCAATGTATACCATGATGTAAAAAAGTCAGGAAAGCAGCGATA TCAGAAGTTTTGTAAAAGAGGAGTGACCATTTAAGACATAAAATATCCTAAATTCCATGT TACAGACTCTAGACTCATGGAAATAATTCAGGCTGATTCCCACCCACGAAAGAGTTTTCA GTCCAGTGACCACATGGCCAAGAAAACAGATTAAGTACAATAAACTCTGCGAACCATGAC ACAGAAGAGGGTTTCTTAACCCAGGTGGTCAGGAAAGGCTTCTCATTGGAGATGTTTGTA AAGTGTCTATTTTTACTATCTCCAACAACAGATTTTTTTTTTAAACTGAGCGTCAGATAG TTAGATAACTTGGCTTAAGTTTCAGTGAGGAAGAACTGGAACTAGATCTGTCTGACTTCA AACCCCCAATGTAGTTTCTATCACATCATGCGCTCACTCTTTTTTTTTTTTTTTGAGACG TAGTCTCACTCTGTCGCCCAGGCTGGAGTGATCTTGGCTCACTGCAACCTCTGCCTCCTG GTTTCACGAGATTGTCCTGCTTCAACCTCCCAAATAGAAGGTATTACAGGCACGTGCCAC CATGCCTGGCTGATTTTTGTAGTTTTACTTCATTAATAATTAGAAGTAGAGTTGGGGTTT CGCCATATTGGCCAGGCTGGTCTCCAACTCCTGACCTCAAGTGATCTGCCCACCTCGACC TCCCAAAGTACTGGGATTACAGGTGTGAGCCACCATGCCCAGCCCATGCTCTCTTATTCT TATAAAAGTGTTATGTTTTAGCACAGTCAGCATAGTAACTTCCACTTCTTATAGTGCTGT TTGCCCAAACATATTTAAAATCTGCTAAATACCATTAGTATTAATAGCTATCTTATCAAG AGACCACTACCAGGAAAATATTGTTTAAAGTCTTTCAGAGAGTACCTGGTGGCTCCCCCA CAAGGGAATTCTAGAGGTGAAAGCTCTGCCAGGCAAATACACATTTTCTAACTGTAAACA AATTGGCATTCTTATACTAACCTTCTGAAATGAAATCACAGAAAGAATTTAAAACCTTTA CATCAATTGTTGCAAATGAATCTATGCAAATAAAGCAACAAAATTATTTTCGAGTTTCTT CCCTTTAGTTTGTTTCTTTAAAGTGTAGTCAACAGATTTTGTATCTAAACACACACATAC TTCTTGAGAAAAACTGTATATATTATAGACACAGCACCAATTGTTTCCAGTATATGCATC TATATTAATGTTTCCTCTTTATATATTCACAAGAATAAAACACTTGACCAGCTGAAAATG TAAGCTATTTATAAAACATGCAGAAAATAAATCTGATTCATGTCTGCAAACCTCAATTGT CTGTGTACTCTTTTTCCTTTCTTTATCAAGACAGGGCTGTAAAATTTAGGTGTACATTTT TCTGCTATCACAAAAGAAATAATGTACAAGTGAACTCTACTACTCTTAGAAGGAAAAAAA TCTCAACTATACATCAAATTTTGGAGCACTGAAGTGGCAGAAATTTTCTATATACTACCT CTGTTCTAAAGAAATGTGGTGCCACTGTTCCGAAAACAAATCTTATAACACATTTAAGTA TAGGTAAACAAAGTACAAATCTCAGTTTTTCAAAACATTTTCTGTACTAATGCTTTTAAC TTGAAACTCTTGACTTAGTTTTGAAGAGAAAAAAAGAATCTCCTTGGCGCTCTTAACTAT TCTGATGAGACTAAGTTCCAGAGAATATTTTACAAAAACTACTTAATTTAACAGTACGCC TTGAAAAGTAACACTACATATTCTAAGTGTTTCTGGAAAAAAAAAAAGAAAAGGAAAAAC CACGACATATTTATAAGCTAACAATTCTTAAGAGAGGGTTACTATGAATGCTGTACATTA ATTTTTACTTTGTCAGATACATAACTTAAGAACCAAATAAGATGATGCATAATTACTTCT AATGATAGAAAGTACGAGTTAAGTCTCCAAAGTAATCGTGACAGTGTTTCATGTGGAACA CATTTCATCTACAAAAATATCCATAAAATACAATCTAGTATACCTCCTAGGTCAATATTA ATGTAGAAACAAGAACCTTCTGTAATAATTAGGTTATTGAGGAAAATCTTAAGATCCATT TTAGACTGAATAATTAAGTCAAATTGTTTGGAATTTAAAATATGTGCTTCATGATGATGA AATAATCTGTACAACAAATAACCATGACATAAGTTTACCTGCGGAACAAATCTGCACTTG TACCCCTGGAATTAAAAGTTACAAAATATTTTTTAAAATATGTGGTTCAAATATATATAT TCAACATGTATCACTTTGTTAAGAGAAAAATAGAAAAATACTCCGTATTTGATCAGACCA TGTAATTCAGATAATAAAACTGTTGTAAGTTTTAAAAAGCCACAATTTCTAGTTTACTCT TTCCTTTGATAGCATTAGTGCAGAAAATATTTTGAGAAACAGATTTGTACTTTGTTTACC TATACTTAAATGTGTTGTTGTAATATTTCTTTTCAAAACAGTGGCACCATATTTCTTTAG AAAGTGCAACGGCACTCACTGTTTAGCAGCATAAAAAATATTATTTGTGAAATTACAATG TACTCCAAATAGAGAAAAATATTTCAGTGTTTTGAAGGGTAAAATACAAAAAGCACACAA GGGGGCAGCAAAAAAAAAAAACAGCAGAGACGGTTTCAAAAGGAACTTTTCTATGGTATT AAAAGACAGGAGAGCAAAATAATGAGTAGGAGGTTTTTGGATTACAGGCAACGTTAAGTT CTTGATGTAGATGCTGGTCACCTGCACCTAGAATAGGGTGTCCTGTGAGACAAAACAATT ATTCTCTATCGTTAAGAGAGATTGTTCAGGAATCCTAATAGTTTGACAATTCTGTACCAG CTGAACATCACTAGAGCTAACTCAGTTGGGATGTAATCACCATAAAAGATTCCATTCCTG TGGTTACTGGGAGTCAGGGAGGTTTAAGCGGAATGTCACTACATTCAAATATGGGAGGGA GACCACTTTCAAAAACGAACTTAAATCCAGAGAACCATGGTTCTTCTATGGTATCCAGTA AGGGGCAATGGGAGTTGGAAGTTGAGTATGGGAAATCAAATTCTGTGAATACGGTTTTTC TGATAAGATGTGTTTGGCTAGCAGATCCTCCGCAGCATCTATTCAATAAGGTTAATCTAC ATGGGAAATAGCCATTTGAAGTCAGCAGTGAAAAATTACCACTTGTGAAAATTTTTTGAA AACCAAATGATCTACATATAGAAACAGAAAAAGAAATTTCTGAAAGGGGCAAATGAGATC CCATTTCAGAAGCTAAAGTGACTGTAGAGTGCAGAAAGAGCACAACATGTAGGATTTCCC AATTTTTAAAAAAATTCAAAACTGATCTTTTAAACCAACTCCCACCACAGAAGGCCTCCC TGACAACAAGGGCGAACGCTGTGAAGGAGAAAACTAAAGGGGAAAAAGAATACTAAAAGA TGCCACACAACCAAGCTGGTCAGACTTTAAAGGCCTCCACTACCAAACAAACCACAAGGC TGGTATCAAAAATGCGCACGCACGCTCACCCACGAATATGTGTGAAATATAAAAGAACCA AAAACATCACAGGGCGCACAGGCAGACACACACTCCACACACAATCCCCACCCACCCCTC GCCCCCCACACACACCTCCCAAAAGCAGGGTGAACAGTTAAGGCACCTAAAACCCCAAGC CGCATAGGCTTCCCCGAAACATTTTACAGTGTAACCAAGAAGCGATTTTGAAAGCATCTG AAAAACGTGCAAACTGTCTTGAAAACAGGGCCTGGCAACTGAGACAGTTTGCAAGCGTGA TTCAGAGGGTCTGCCAAGGAAACAAAAGAAGCCTCCCTCCTCCCCGTGAGACCGCACATG GCACGAGAGGTGCTCCAGGCGGGACGCATTTTAAGCGAGGCAGACAAATAGAAGTCTGCG CGAGCGCAAGCGGTACATACTAGGGATCGCTATCTGGCGAGGATGGGGCCATGGAGTTTC CATTGGTTGGGGAACCGCCCAGCTTTAGTTTCTCCAGATATTCGGCGTGCACGGGCTTGT GGCACTGGAGAACCTTGATGGCATCTTCGACTTTGAACCACTCTCGCTTCCTCCCAATGC TAACCGAATCTTCCCAATCCTCCAGCAGCTCCGTGACAGTCAGTACATACACGTACGTTC TGTGCTTGCGATCCTGGTTCTGTTCGAAGACGCCCAGGAGCCGGCCTAACTTCCCCTTGA CTCCCGCTTCTTCGTACACCTCTCGGACCGCCGCACCGCCCGGCTCCTCCTCGGGCTCCA TGCCCCCGCCCGGCACGATCCAGCGGTCCGGGTACCGGCTGCTACTCACTAACAGGACCT CGTCCTCGCGTTCGCTCCGGAAGCACAGGCACGCCGCCCGCTTCTTGAACCCCTCGGGGT CGTAGGTCCGCGTCTGGTTGGGTTTGCACTTCATCCTCGAGGCAGCCTCCTCGAGGCAGC CTCCTCTCGCCTCTCGCTGCTGTGTGGGCCGCCGCTGCCGCTGCCGCCGCCGGGGAACAG CCGAGGTGCTGGGAAGAGAAAGGGCCGAGGCGAGGGGCGGGGAAAGAGAGGCGCCTCCGT CTGCCCGCGAGCCCGGGGAGCGGAGG bcftools-1.21/test/csq/ENST00000375992/ENST00000375992.fa.fai000066400000000000000000000000201467060157400215550ustar00rootroot00000000000000X 6626 23 60 61 bcftools-1.21/test/csq/ENST00000375992/ENST00000375992.gff000066400000000000000000000024271467060157400212100ustar00rootroot00000000000000X ensembl_havana gene 21 6606 . - . ID=gene:ENSG00000196368;Name=NUDT11;biotype=protein_coding;description=nudix (nucleoside diphosphate linked moiety X)-type motif 11 [Source:HGNC Symbol%3BAcc:18011];gene_id=ENSG00000196368;logic_name=ensembl_havana_gene;version=4 X ensembl_havana transcript 21 6606 . - . ID=transcript:ENST00000375992;Parent=gene:ENSG00000196368;Name=NUDT11-001;biotype=protein_coding;ccdsid=CCDS43952.1;havana_transcript=OTTHUMT00000056579;havana_version=1;tag=basic;transcript_id=ENST00000375992;version=3 X ensembl_havana three_prime_UTR 21 1758 . - . Parent=transcript:ENST00000375992 X ensembl_havana exon 21 1759 . - . Parent=transcript:ENST00000375992;Name=ENSE00001469078;constitutive=1;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001469078;rank=2;version=3 X ensembl_havana CDS 1759 1759 . - 1 ID=CDS:ENSP00000365160;Parent=transcript:ENST00000375992;protein_id=ENSP00000365160 X ensembl_havana CDS 5961 6454 . - 0 ID=CDS:ENSP00000365160;Parent=transcript:ENST00000375992;protein_id=ENSP00000365160 X ensembl_havana exon 5961 6606 . - . Parent=transcript:ENST00000375992;Name=ENSE00001469091;constitutive=1;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001469091;rank=1;version=3 X ensembl_havana five_prime_UTR 6455 6606 . - . Parent=transcript:ENST00000375992 bcftools-1.21/test/csq/ENST00000375992/ascii-art.txt000066400000000000000000000003331467060157400212770ustar00rootroot00000000000000 6453 ATCCTCGAGGCAGCC A 6444 6454 eeeeeeeeeee.......... TTGCACTTCATCCTCGAGGCAGCCTCCTCGAGGCAGCCTCCTCTCGCCTCT TTGCACTTCA--------------TCCTCGAGGCAGCCTCCTCTCGCCTCT TTGCACTTCATCCTCGAGGCAGCC--------------TCCTCTCGCCTCT bcftools-1.21/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.txt000066400000000000000000000004411467060157400262310ustar00rootroot000000000000006453 ATCCTCGAGGCAGCC A 5_prime_utr|NUDT11|ENST00000375992|protein_coding,synonymous&start_lost|NUDT11|ENST00000375992|protein_coding|-|1M|6453ATCCTCGAGGCAGCC>A 6453 ATCCTCGAGGCAGCC A 5_prime_utr|NUDT11|ENST00000375992|protein_coding,start_retained|NUDT11|ENST00000375992|protein_coding|- bcftools-1.21/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.vcf000066400000000000000000000010701467060157400261670ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO X 6453 . ATCCTCGAGGCAGCC A . . EXP=5_prime_utr|NUDT11|ENST00000375992|protein_coding,synonymous&start_lost|NUDT11|ENST00000375992|protein_coding|-|1M|6453ATCCTCGAGGCAGCC>A;type=ENST00000375992:51239295-ATCCTCGAGGCAGCC-A, could be realigned if del moved to right bcftools-1.21/test/csq/ENST00000378322/000077500000000000000000000000001467060157400166515ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000378322/ENST00000378322.fa000066400000000000000000000535571467060157400210220ustar00rootroot00000000000000>1 1:3547331-3569325 TAGTTGTATAAATCAGCAAGTATTTATTTTAAATAATAAAACTACAGTTTTATACCATAC ATATTTACAAAAATGCTTTGCTATAGAAAAATAGAATCAATCACTGAATCCAGACCACCA CAGTGGAGAACCTCCTGGTGAAGCTGTGTTTTTTCCCACACTGGAAACACAGAGTAGCCC TGTTTCTGCACACGTTAGTGCACCGCTGCTACGTGTGGCCGCCCAGCTGTCTGCAGGCTG TGCCGACCACTGCCTCTGTCTCCAGGAAGCAGAGGCAGAAGTGATCCTTGCTGAGGAGGG CCATCGAGTCTCCGCTTAAATGCCAGCACAGAGAGAGCACTGCAAAGTCGCCTAGAGAGA GACAGGTGGCCAGAGGATTACAGCAGGGGAGGCCCAGATTCTGGGGGATGGGCACCCCCT TGTCCTGCAGGCCAGCACAGTGCCTGGAGTGACCCACATAGGCAGAGCCAGGGTGGAGCC CCAGAGCTGCCTCAAGTCAGGGAGAGGCTGCTTCTAGCCCATAAAGCTGAGGGCAGCGGG TCCCCTGTGTGTCCGTCTTGAGGTTTACGCAAAGACTCTGAGGGCAGTTTCCCTGGAGTG CTGCCGGAGACAGCAGCTGGGCTTCAACAGTTCAGCCCGTGTGATGCCAGACTGCACACA GCAAGGCTGCCACGTCCGTGGCCTCGGGGATGTGCTTACCTTCCCCAGGCACCTGCACCG ACATGCAGCCCGCTGGGGACCACAGGTAGAGCCTGCTGCCTCCCGTGCAGATGGCCAGCC GCGGCTGCTGCGGGTCCCACTGAAATGCGCGCACTGGGGACAGCTGCTCGAGCACCGCGA ACAGCCTCAGCTTCTGAATGTCCCAGACCCAGACGGCATTGGGAATGTTGTCTGAGGAAG GAAGGACAGGGCACCGGTGTCATCCCTGCCTGGCTCCTCTGTGTTGGCCCTGCCCCTCTG CTCTGCTGTTGACACCACAGGAGGGGAGGGGAAGAACCGGTGGGGTGGGGCGGCTGCACC CTGCAGTCTGGGTTCAGTTGGGCCCTGTAGGGCTCCTGGCCAGGGCCAGGGTGGCCATCA CGGGCTGTAAGGGGCCCAAATGTGTTTCTTTCTTTGGTATTTTTTTTTTTTTTTTAGCCC TTTACAAATGGAGAAACCCTTAACAAAAGGCGGGCTGCAGTGTGCCCAGCCCTGCTTTCT ACTCAGCAGAGTGGAGCAAGTGAGCAGGGTGGAGGCCTCCTGACTCATGCGCGGACCTGC GGCTGCTGCAGGACAAAGGCCCAGCGCCTCCAAGGAGCTTCTGTGAGCACCTCGGCTACT GCAGAAACGTGAAAGGAGGTGACGTGTCGGAAACCCCCAACTTCATTTTCTTTTCCAGTC GCTTCTACACCTGGGGCCACAGGACACAGTAAAGGGTGAGACAGCACCTGCGTCAGCACA ACTGACCGTTCCTTGTCGCCAGGAAGTAGCTGTCAGGACTAAATGCCAGCATTCCTATGC CGATTTTCGGGTTTGCTCTGTCGGTAACAGGTTTCAGTGTCTGTAAGGAGACTGGGACAG AGGCGATCTCATCTAGAACACCAACAGGAAGAACACGCCATTGTCACCCTTTCGGGAAGT ACGCACGCGGCTGAGAGGCTGCTGTGCCTGCATCGGGCATCGCGAACCCAGCTCCTCTGT TCAAAGGGGAGGAAAGTGCGGCCCAAGGGCAGGAAGAGCTAAGCAAAGCCTGGCAGCCGC AGCGAGGGGCCTGCCCGCAAGTGCCCCGGATGAGAGTGGCACCATCACCTGCCAGGCCCG ACTAGGTGGGGGGTGGACCCCACGTGCCAGGGGCTGACTGGAGAGGGACATGGACAGGTC CTAGCTGCAATCTCAGCAGCTCCAACTCCTCAGCACTTTTCTGTCGACTACCAGCATCTG AGTTCACAATCCCTTCCACCTCAGCGTCAGTACCCTTAGACTTTCCGGCTGTGGAAGAAC CATCATCACAGCAGAAGCAGGGGCTGTGGAACAAGGACGCCCCTGGGCTCCTGGGGAGCG CCTCCTGTGTGCCAGGCTGCACCTGTCCTGACCCCCATCCTGAGCACACACCGAGCCCCG GGGTGGGCCCGTCGGCACTTGGGGCACCGCTTCCTCTACCTGCAACCTTCAGATGCCCTC ATGCCCCTGTGGGATGGGTGCTTTTACTATGCCCATTTCAGCGATGAGGAAACAGACACA TAGGAAATGCCCAGAGTCAAGAGGCTGCATCAGAACCGGGCCTCAAGCCGGAGACAGCGC TCGGGAGCACCGCCGGGTTCCAGACCCACTCTGAGCGCCACCCACGGAAAAGTGTTTCTT TGAAAAACATCATTCTCGGAGCTCCGGAAAAACATCCCCTCGGAGCTCCCGCTGTCAGAT CCGGGTCTCCAGGGCTCATATTCAGTAACAGAAGCCGCACCTTCACGGCCCACTGCGCAA TTCAGACCCTAGTCAACCTCCAGCCAACAGGCTGAGGGGCACACTGGCTGGAAGCATGGA AGGGAAAAAAAGTTTTTTTTTTTAAACATAAGGAACATCCGAAGTTTATCTGGACAACGA GGAATCTTGCATTAAAAAAGGAAAACAAATGACATCACATGTGCTACTTACATTTACTCT CTGAGCTCGGGAGAGGGCCGGCCCCGGCCCGGGGCGGCGGGAAGGAGAGGCAGCCCAGTC CCAGCTGTGGGCTCTTCTCGGCCTCCTTATACACCACCTGAAAGACACAAGGTGGCCACG CCCGGCTCAGGACAGGGACCCGGAAGCCAAGGATGGACGTGGCAAATGCCCATGACAGCG CATGGTCAACAGGTGTGCCTGCCATGACAGCTGGTCCTGCTGCCACCGGGAGAGACGGAA GCACGAACCCCGCAGTCCCGAGAGCTGAGATCACCCAGCCACCCTCTCTCGTGTCCTGCT GAGGAGCCCACCCTTTGAGACACAGGCAGCAAATGTGTGCCCTGTGATTACAGACGGGAG ACCACTGCAGCCACCATCATCCAGCAAGGGAGTGGGCTCAGCCTTCCCTCCGTGATAAGA GGATACAGAGAACACTTGCACCAACACAGCAGAGGCCCCGGGAGCAGCAGACACAGACCC GAGGTGGGGGCATCTGTGCCCGAGAGCCTGGCAAGCAAAGGACAGCGGCCCAGGCTCAGT GGAAGGCGGGCAGCCCCTACGCCCCTGAAGAGCCCCAGGTAAGGGAGTCACCTGGCCTGG TTCATGCCTTTAAAGCATGCTCTGCTGCTGTGTGGCGAAGGGATTTGGAGAATGCAGGAA TCACAGGCAAACCTTCAGGACCTGTGTGGCCAGCCCTGCTCGGGCTCACCTGTCCAGACA CCCTGGCCTCCAGCCACACAAGCCACTGGCCACGTCAGGAGGCCCCTCTGCCTGAAACAC CCTTTCTGCCCAGACACCGCGCAGCTCCTCCTCCTGGTCTTCACTTAAACACCCCTCCAG GATGCATCCCCGGCAGTGGCTGATCTGGCATGCGCAGCCCCAGCCACTCACTGGCCTCTT CATCGAATCCAAGCCGCCTTTCACTCAGCTCTGTCGGTTACAGGTCAACACCAGGAGGGC AGCATTTGTCTCTGGCTCCCAGCGCAGTGCCCGCTGCACACATGGATGCGTGGCCCACTC CTCGGGGCCTTTGCATTTCCTGTTCCCTTGGCCTGGAACGCTCCCTCCCCGAGTCCCTGA TCACTGGTGCAGCATCTGTGCCTGCGATCCCTCGCTGGTGGCCACTCCCTGCCACCCCGT GGAGACACCCAGCTCTCCAGCCCCTTCCCTGTCTCTCCAGCCGCACTCTGCAAGTGCAGG GGTCTGTCTCTTCTTCTCTGGCTGCGGCCCAGAGCACAGTGCCTGGCACGACAGCAGATG CCCAGTGTTTGGGGGCAGGAGACCCTGGCCACTCTGTACAGCACAGGGATCTGCATCCAG ACAGACCACAAAGGAGAAAACTGGACTGGGGTGGCAGCGGCAGAGGACAGGCCAGGGCAA GGCCCACTTCAGACCCTTTGGGCAGCGTGGAGGAGGAAGAACAAAGGCCAGGGCAGGGCC AGACGCGTGAAATGTCACAGTAGCAAGTTTACGGTGATGGAAGTGCCCGGTTAAATAATA AACCACAATCAAGAAAGCAAAGTGAAGGAGCAGTTTCCCACCGCCCTCCCCAACAGCCTG CTCAGGCAGAAACACGTGTTCCAGACTTACTATCTTGGGATCATTAATGGCTGCAGGATG CCCAAACTCCGTGATCATTTTCCAAGTCACGTGATTAAGGATGCGCACCTGAGGAAGGAA ACCATGCACAGGTGAGGCAGGGCCCGGCCCGCTGGGCGGTCGGACTTCCTGAGTGCCCTG CACTGGTTCCCACCTTTCCATCATAGCTCCCAACTGCCAGGAACTGACTGCTGGGGCTCC AGGCCACAGACTTGATGCCCAGGGACCACTCGTAAGCGCTGTACGTGGACAACAACCGGC CATCCAATGAGTACAGCAGAATCTTGTACTGCAGATGAGACATTTCAGTTAATAATGAAT ACACCCCCGTCGCCAGGAACACACCACAGACGCGGGTGCTGCAGAGTGACATTGGTGCAG ATAGCACAAAGCTGGCAGGACTGTCCGCGTGGCCGTGGAAAAGCTGGAACTGCCAGCTAG TACTGAGATAGTCACGGAGAGGCAGTGAGAGCATGAGGAAAAAGGGGAAATTGGGAGGTC AACCTAATGGCTCGCTGATAAAAGTTCAACTCGGCCGGGCACTGTGGCTCACGCCTGTAA TCCCAGCACTTTGGGAGGCCGAAGCTGGCAGATCACTTGAACACAGAAGTTCAAGAGCAG TCTGGGCAACACGGTGAAACCCCATCTCTACAAAGAATACAAAAATTAGCCGGGCGTGGT GGTGCATGCTTGTGGTCCCAGCTACTTGGGAGGCTGAGGTAGGAGGATCACTTGAGTCCA GGAGGTCGAGGCTGCAGTGGGCCGTGATCACACCACTGCACTCCAGCCTGGGTGACAGAG CAAGACCCTGTCTTTTAAAACAAAGCTCAACTTGTTATCTGAAATAAGATAAAGCAAACT ATATTGCAGCATTCAGAAAGCATGAAATTCCGGGAAAAGCTCTCGAAAGCAAACATGTCA CCTGGTCATCTTCATACCTCCAAGCAGGTGTCCCACACTGCCAGCACACAGCCGTTTGGG GCCCACTCAATCCCTGTGAGATCCTGGGTGTCCGTATCAAAATGCTTCCAAAGGAAGGGG GGGAAACATTAAATTTGGAAAATATTTTCGTAAATAAATAATTGCATTTATGACTGATGT TCTTAACGCACTTAATTTCCTTATATAGAAATTGACAAAATCTCAACAGCTCTATCCTGG AAATGCATGAAATCCCTGTAGAGCTGCTGCTGGGGCTGCACCGCCACAGATGCCAGCGTC AGTGCCTGGCCAGCCCCCAAGGGCGGCTTGGTCTCCCCGCGCCTGCACTCGTGTGCACAC TCTCCCCCTCACCTTTCCTTGCCTGGCCAGCCCCCGAGGGCGGCTTGGTCTCCCCGCGCC TGCACTCGTGTGCACACTCTCCCCCTCACCTTTCCTTGCCTGGCCAGCCCCCGAAGGTGG CTTGGTCTCCCCGCACCTGCACTCATGTGCACACTCTCCCCCTCACCTTTCCTTGCCTGG CCAGGCTCACTCCTTTAGACCCAGCTCAGACAAGTCCCTTCCAGAGCACTGCCTGGATCC CGGGTTCTGCACTCTGACAGCATTCCAGAGGTTGCTCTACCTTAATGATGGATTGTGCTG GAATCGTGTTCATATGTCTGCTGTGGGGGCAGTGCCCTCTGTGCCTGGGCACCTGGCAGA GCGCCCTGCCTAATGCAGGCCCTCAGTCAAGGTGAACTTCCACGTCCCCCCAACTCCCGA CGTGGCACACACATGCGCAAACACCATCACACAGGACAAGGAAAAGGGCTCAAATGTGAC AGCATATTCACTTTTAAAACACCTGGGCACGCGTCCTTTTCACCAAGTCTCCTGAACACA CAACCGGGTGCCACTGGAAGTGATTCGCAGCGCACCTGCCCTTTGTTAATACAACATCAC CTTGCTCCATATCCTACCAAAGATCCCCTGGAATCTGGAAGGATCTACTTCACTCGATCC CTCCACAGTCAGCAGGACAACTTTATTCCAGTCTGGGGGACGCCTTACCCGCAGGAGCTG CCAATCACTGCAGACGAAGATGCTCACGTAATCTTTGCAGTCGCGCCGTTCTGCCAGCGC CATGTAGCGGCCGTCCCTGGTGAAGGTGATTCCTGTGGGAAGAGGCAAATGCACTGAAAT CAAGCGGCCACAAAATCAAGCAAGAGAAACCACAGTAGTAATTCACAAGGAAGGAGGAGG AAAAGAAAGCAGAGGTGAAAAGAAGGGAAATGGCACAATGCCGAGCACTGCTCCTCAGAC AGACAAGAACATTCTAGCGCAGAGGAGAAACCCAAGGCACGGTGCCTTCACCCTCACAAC GCAGTGTGTGCTGGGGGAAGCTGTACACACACAGGAGCCGGTTTGCAAGGCTCTGTCAAA AATACCAAGTGATGTGACCTCTGATTAATCACAAATATGAGTGAGAAACACAGGCCTTCG AGTCCCCCCATGTCTAAGCTGCGGGACACCCAGGGCTATCTCCAGCTAGGCAAAAGGCAG CTGGTTCCTACCATATTTATTTTACCTTTGAATTTAATTATTTGGAAGAAGTAAACTGAA GATGAAAATGTGTGGCCAGGCATGGTGGCTCACGCCTGTAATCCCGGCACTTTGGGAGGC TGAAGCAGGTGAATCGCTTGAGCCTAGGAATTTGAAAGGAGCCCAGACAACTTGGTGAAA CCCCATCTCTACAAAATATCAGCCGGCTGTGATGGTGTGTGCCTGTAGTCCCAGCTACTC AGGAGGCTGAGGTGAGAGGATCACTTAAGCCCAGGAGGTCGAGGCTGCACTGAGCTGTGA TCGTGTCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTCAAAAAAGTAATAA TAAGATGAAAATGTGGAAGAAACTTTAGTTGAAAATGTTAAACTCTTATTTTCCAGTTCT GTATTAGCTTAAAAAGCCCTAGGCCAGAATTCATCATTCCTGAGTGAAAAGAATACCTCA AATGACGAAACCACGGTGTCCACTCCTATCAAGAGATATGTATCTCATCTGGAGGGACGC TAATATTCCAACTATAAGAATAAGAGTGTGACTGCATTGCATTCAAATGCAATTTCCAAA CCGCTGGCAGCAACAGAGAAAAATGAAAGCATCATTCCAACTGTGTATGTTTCATTCCGC AAAAAGACAGTGCGGTGTCGTCCAGGACTCAGGAGTGGCACCTCCCACTAGCTCTGCGCG GTCCAGTTAGACGCGCTGGCAGTGGGCCACCCTGCGCCGGCCCCCTTTCTTCCAGATGGC TCACAGGCTTCCACAAGGAAGGGACACTGGTCACATATCCCTCTGGGATGCCCAGAGATG ACAGGCAAGACCTCCCCCTTTCGCAGACATCATATTTAGTCCACAGAAGAGAGAAAGCTC AGAACTGGATGCCTGAGGTGGGCCTCTCAACAGGCATCGGCTGGAAGGGGTCTGAACGCC CAGCTCTGCCGCCAAGGTCAAGGGGACCGGCATCAACGCCACCGTTCTTCCATGTCTTAG GCCACGTTGTCTTGAGTCACTGTGGTCATGTTTTAAAAGGGGACTCTTGCCTTTTTGAGA CACATATGGAAATATTTACAGATGAAGTATGAGGAGACCTAAGGTCTCCTTTAAAAGAGC CCAAGGGGGTTGGCTATGTGTTGATATGCTGCTGAAGCTACTTCTGCCTCTTTGAAACTT CCCGTGACAAAAAAGTCAAACAGCTGCAAAGAAATGGCTTTTGCGTGGCTCCGATCGACT CACCCTGCAGACAAGCTTTCGGGTATTTGATGTAAGACACGGATTTTGTGCACAAGGACC AGACGGTTATCCGCAGCTGTTGGGGGAAAGGGGAAAGAGAAAGGAAACACTTCTTTAGCA TCATCAGAGACCGTCTCAATCCTCAACCCGCCCACGCGTCCCCAAGCACAGGCCTGACTG CTGGAGTGGATCTATCAGGACCTGGGGGATGCCTGCCCTCCTACCGGAATATTCAAATGC GTATTTTACTGTGGTTACGGTAAATTTGGTGTTCTTGGTTTTCTGTTGTTGTTGTTTTAT ACCAAAATTGAGTGACACAAAGTTAAATCCAAGTGCTTTTTCATTAGCTTTTTCAAAGTG ACCATAGGTTGCATGTTATAATAACCCTGAGTTACTCAGAGAAAAATCTTGATCTAGAAA CCACCACGGGTTCAGTCTCCTTTATGGGAAGACAGAGGATCTGGAGATTGGATGCAGCCA CTCCGGGACTCACCAGGGGGCTGTGAGCCTGCATCTGCAGCCCTGAGGCAGGAGCAGCCA CTCAACACCCAAGAAGGTGTCCGTCTGCCTCCTGCGTGTGCTCGCTGGCCTGGCTGCATC TGCAGAGGGTTCTAGAACATGCGCTGCTGGACTGTCCACTTTTCCACCCCTTTCCCTGAC TCAGGGAGCTGAGAGCTGACTAGGCTGGCACAGTGAGGCCAAAAGATGATTTTCTAACCA GGCCGACGAGGGCGTGCCTGCTGAGGGAGAGGCACCGCAGTGGGTGGTCCAGCCCTCCCC GTGGCAGCGCCGCGGGACTTCCAGGGCTGCTGTGTCCCTCCACCTGCATTTCCCACTGAG ACCCCGTGGAGCCTACCAGGGAATCATCTTGCTTCCCACATCCCCGGCCCACTGATGAAT CTGGTAGTTAACTGAAATATGGCCGAGGTGCGGGGACACAAGGTGCGGGGTGGGGTGCTG ACTGCCAGCTCCGTGTGTGGGGACACAGGGCTGCGCAGCTCCATGTGGGGTGGGGTGCTG ACTGCCAGCTCCGTGTGTGGGGACACAGGGCTGCGCAGCTCCATGCGGGGTGGGGTGCTG ACTGCCAGCTCCGTGTGTGTCAGGCAGGGGTCCTCGCTGAGGATGAGGCCCGGGGTGGGG GACCGTCTCCAGCAGCGTAAGTGGGGCCGCAGCGTGTGGGGCACAGCATGTCCACAGTGT CACTCCTGCAAACGCTGCCAGGTTGTCAGTATAGGATATTAACAAATGATTTAATTTAAA TGTCTACGCATCATCTCTTCTTACAACAGAAAAGAAAATCTGATGTCTGTAATTGTTTCT CCAAACAACATATACAGCGTTCAGGAGAGAAGTCCTGAACACACAGGTAGTGGATCAACG AGCTCCAGGGGTCACGTGGCAGCACGGAAGGGCTCCTGTGCTGATGCTGAACCCGAAACA CACTGGCCGTTCTGGGGACCATGCCTCGGAACTCCAGCTGCACAGAGCACTTGCTCCTCT AACAGCTCCACAAGCTGAGGCCAAGGAGGGCGCTGGGGCCTGAGCGAGGAAGCGTGCTAC TTCCCACCAGCGTGTCTGAGGCTGAAACCTTGCCCAAGCCTCTCAGACTCAGCAGGGTGG GTGCAGCGCCTGAGGCTCTGAGCATCAGCAGGGCGGGGTGGAGCGCCCGAGCATCTCAGC ATCAGCAGGGCGGGGTGGAGCGCCCGAGGCTCTGAGCATCAGCAGGGCAGGGTGGAACAC CCGAGGCTCTGAGCATCAGCAGGGCGGGGTGCAGCGCCCGAGGCTCTGAGCATCAGCAGG GCGGGGTGCAGCGCCCGAGGCTCTGAGCATCAGCAGGGCAGGGTGGAACGCCCCAGGCTC TGAGCGTCAGCAGGGCGGGGTGGAGCGCCCGAGGCTCTGAGCATCAGCAGGGCAGGGTGG AGCGCCCGAGCATCTCAGCATCAGCAGGGCAGGGTGCAGCAACGGAGCATCTCAGCATCA GCAGGGCGGGGTGGAGCACCCAAGCATCTCAGCATCAGCAGGGCGGGGTGCAGCGCCCGA GCCTCTCAGCATCAGGAGAGTCCATGTGCCACCCAGGGCAGAGACCTGCCCTCCAGAGCC TACTGCAGAGTCACAGGAGAAAAGCACATCTCCCACCTGTGGCCCTGCATCCCTGTGGGG TGCGCCTGGCCGAGGCTCCCCACTCAGGCACATCTTAGGAAACACAGGGAGCACTTTAAG CCTGATTTTTACCTTCATCTCACAAAAACAAAGAAACAAAAACCTTTAAAAGATAACTTT GCAACTTTTAAAAACCCAATAAGAAAAAAAGGTAGTTAAATATACACCTTCATCAGCGCT GTTACCTTCCACTGACCACTGGAGAAGCCAGCGGAGGAGACCCGTGGGATGGGCTCCACA GCACTCAGCAGCAGGAAGAAAGGACCAGAGGGATCCACATGACCCAGAGCACTCAGGAGG GAAGGAAGGGGCCGCTGATCCACGCTACGACCCAGTGTGCTGAAGACGGAAGGAACGGGC CACCGATCCACACCACAACTCAGCATGCTCAGGGTGAGAGGAATGGGCCACGGATCCAAG CCATGACCCAGTACACTCAAGACGGGAGGAACAGGCCACTGATCCATGCCACGACCCAGC ACTCTCTCCACACCATGACCCAGCACTCTCAAGATGGAGGAACGGGCCACTGATCCACCC CACAACCCAGCACACTCAAAACCAGCAAGATGCCAGGGAAAAGGAAGCAGACGCACAGCT CCACGCACCATGGCTCTGTGCAGATGGGATTCCGAGTAGGCAGTGCTGCTCGCCCCGCAG CAGGCACCGGCTGCCGGACACAGGTGGGAGACGGACTGAGCACAAGGGGCACGAGGAGCC CCATGCCACGGGCGAACAGTCTTGGTCCTGATTGTGGCGGCAATGACGTGCAAAGTGACT CACTCAACTGTGCTCTTAAAGTGGGTGAATTCTCTTGCTTATAAATTGTTTTAATTGCCT TTATTCAGATATAAGAAAAAGTCTGCAGTCTGGATATATTTTTAAAGCTAACTATAGACT ATTTACAACATACACACTCAAGTTTAAGGATGCAGAAATGTAGAAGGTAAAAGGATAGAA AAAGACATATCAAGAAAATCCTAACCAAGAGAAAGGTGGCACTGCCGCATTCGTACGGGA TAAATCAGACTCTGAAACAAAAAGAACCGTGAGACATAAAGAGGAATACTTTACAACAAA AGGCCTGTGCCACCGCGGAATCATGGGAACCGCTTCACTAGGAAATCTGTTTACAAACAG TTAAAAGTTTGTATGCAGCTAACAACAAAGTCTCAAAAATACATTTAAAAATCTGGCAGA GCCGGGCGCACTGTTGTGCACCTGTAATGCCAGCTATACAGGAGGCTGGGAAGGAAGGAT TGCGTGAGTTTAGGAGCTCGAGACCAGCCTGGGAAACAAAGGGAGACCCCAACTCTACAA AAAAATTGTTTTTAAAAAATCTGACAGACTACAAGAGCAATGAAGAGGAATCAGTCCCAT CAGATATTCAAACACACCATAGAACCTCAATAATGTAGACAGTGTGGTGCTGGCACATAG GTGGACCAACAGTGGACTGGAATGGAAACCAGAAGTGATCCTGCAGGTATAATGGAACTG AGCTCCTGCTATAGCTGGTGAAGATAGCCTTCTAAATAAATGCTGCTGGGAGCTGGGCAC GGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCAACTGAGG TCGAGAGTTTGAGACCAGCCTGACCAACATGAGAAACCCCATCTCTACTAAAAATACAAA ATTAGCCAGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGA AAATCGCTTGAACCTGGGAGGCGTAGGTTGCGGTGAGCTTGGATCACACCATTGCACTAC AGCCTGGGGGACAAGAGCGAAACTCCATCTCAAAAAAAAAAAAAAAAAAATGCTGCTGGG AAAAGGTAGAAATGGATTCAGACCCCACAGTGTGCCCCACTACGTGAACCTGCTTCATTT AAATGGAGCATGTGTGAGCGTCTGTGTGTAATGAAACAAGATAGGAAAGCACTCAACCTC ACCGAGAATTAGGGAAACGCAAACTAAATCCAAACTGCAGTATCATTTAGTCGCCTGGAT GGAATCATTGTAATCCTGCCACAAAAGCCTTGGCAAATGAAACCCCTCCGTCTGCTACGG CCAAGCAAGGCTCTCCTAGAGAGGCTCTCCGGGTATGTGCCCAGGAGACGGGGACAACAC GTTCACAGCCACACCGTCCGTGGTGACGCACACGTCCAGCAGGCGAGGACTGAATGGCGT TCCTCACGAGGAAGGGAAGGCCCAGCGATGCCTGTCAACACGGAGGAGTCTAAAAGCAGT GACGGGGAACAGCAACAGCAGAGACTGCAAAGTACAAGCCCCTATAAATCAACTTTACAC TGCACAGCAAGCAATGTGGTGTTTAGACACATCTGTACAGTGAGACTCAAGAACAGTGAG GATGTGATTCACGCAAGACGTGGGGCAAAGGTGCCCTCAGGTGGGGAGGGCATTGCTACG AGGAAGAGAAGGGCTCTGAAAGCGCGGCAGTGTTCCGCTGCAGGCCTAGGGGTGAGCCGC TTTTGATGACTCACTGAACCTCGTCTAATGGGCGCAAGCTTGCCTTTTCACGTTAAAATG CAAGAGGCAGGGACGTCTCCCATGCTCCACAGCACCCTCACGTGGGGTGGCGCCTTCGCA AGTGGACTCAGCGGCCCCACTAACCCCCGAAATGGGGTCGCGCCTTCGGAAGGGGACCCA GCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCG CTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCC GGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGG GTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCT TCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGG GACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCG GCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTG AGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGA CATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTC GCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCG GAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGAC CCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCC CCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGATCCAGTGGCCCCGCTGAGC CCCGGACATGGGGTCGCGCCTTCAGAAGGGGACCTAGTGGCCCCGCTAATCCTCGAACGG GTCTGGTCCTTGCTCTTGTGAATGAGACTGATGGACGGTGCCCGCAGCTCACTTCCTGGC CAGCACGTCTGGAATTCCGGTTTTGTTTCCTCACTTGCAACCATTAAAGTTCGCATGCAA AGCTGGAGACACATTTTGACATCTTGGTCAAGATGCCCCATGCCTTGAGGTTACCGGTCC TCATCCACCACCTGGTCTTAACGTTTCCTCTAAGGCCACCAGCAAAGTGGTCATGACCTT AGTCTTAGGTTGAACAATGTCATCTAAATGTACTCTATGAAAAATCAGTTTGTTCTGTAG CAAAGGTGTTTTCAATATTGGTGTGTGTGACATGGGATGCTCAACAAAACCAGGCTTTTA TCCATCTTTTAAGGTTTCTAAACTCTATAGATGGTAGTTTTCCTTCTGGGCCATTTAATA AGATAATACAACAAGGCTGACCCCATGACATGAGCCCTTCTCAAGGGCAGATTTGGGCCC AAAGCATTACAGGCCTGAAGACTGTTAGACACGGCTGCGTGAAAAGCTCAAATTATCCTC TCTGAAACACTCAGGCCGAAAGTGCCTTCCAATGTCAATACATAGTGCGGAGACATTGGT GGGCCTTTGTTTCCTGTCTTATTCTCTGACAGCCCATAATAGCAGACATTAGATTTGGAG TATTTTTTAAAATCGAAACTGAAAAATATGTAAAGCCATCCAGCCATCTGAAGCAGTTGA TTCAGCAACCCTCATGGCTGGATAAAACTTTATCCCAGCCGATGCCAGCTTGAAAAAAGC CGAATGAAACCCTACAGAGCATCTGCAGCCACACGCTGGGAGAAATCCTCCCAGGTGCCA TCATCTACGTGGTGTGCGCGGCGCAGCGGGACGGGAGGGCTGCAGTGTGGTGTGAGCGGC GCAGCGGGATGGGCGGGTTGCCCCGTGGTGTGCGTGGCGCAGCGGGACGGGCGGGTTGCC CCGTGGTGTGCGCGGCGCAGCGGGACGGGCGGGTTGCCCCGTGGTGTGCGCCGTGCAGCG GGACGGGCGGGTTGCCCCGTGGTGTGCGCGGCGCAGCGGGATGGGCGGGTTGCCCCGTGG TGTGCGCGGCGCAGCGGGATGGGCGGGTTACCGAGGTGCAGCCAGCAGCCCAGACAGCTA TGAGCACTCAGTGGACTTGGGCCCAAACACTGGGATCCAACTCCATCAGAAAAGCACATT ATTAAAGGAATTCGTCCATTTTTCTGTATCTTAAAAAGACACTGCGGACACCAAAGACCT GGTATCTAAACACTTGACATATGCCTAATTTTAACTTAAAATGCAGTCTCCTATCCCAGA TCCCTCTGATTTATTCTCGGATGTCAACATTCCCCTCCGCGCTGAGCTCAGCACGGAGGC TGTTGTGCGGTACCTACAGCAGGTGAATGGGCGGCTGCCGACCGCCCCGAGCCACGCCCC CAGGCCAGGCTCCTGAAGGAAAGGTGCGAGCCGGCTCATATCACAGCGCATTTTCTATCG TTGAATTAAAGGGAGTGCCGAAATCCTAAAAAATCTAAATTAAGATTTTTAAAATGTTTT TTCTTCAAAACTGGACAAAAGATCAGACAATAATACTTAGTGGCTTATAATGCTCTGACC TAAAATATACACACCACTATATACGCTCCCCGGCTCCCTCCAACCCCGCCAATCTACCAG CCACTCGGGAGCCACCTCAGTCATCAGACCCAGGGCAGCAGACAGTGCCTGTGTTCACGA CACCCTTATCTGACTCAGTAGCAGCCCAAAGCACGGGCGGTGGGGCTCGCAATCTGGATA CGCCAAAGAGAAGCCACAAAGTGCTTCCTTTAAATGACGAGCTGAAAGTTCTTGACGCAA CAAGGAAAGAAAAAATCCTATGCTGAGGTTGTTGCTCAGATCTTCAGTAAGACCAAATCT TCTATCCATGCAATTATAAACAGTATATTGTTATCCTTGTTCTATACTATGATTGTTGCT AATCTCTTACTGTATCTAATTTATAAATTAAATGTATCACAGGTATGCTGTATAGGAAAA AACACAGGAAATACAGGGTTTGGTACAATCTGAATCCCCTGGTGGTCTTAGAATGCATCC CCTGAGGATAAGGGGAGACTAGCATACTCCAAACACACCCCCTCTCGCACTCCCCAGCTG TTTCGAGAGCAGAGGACAGGATCACATGGCCAGTAAGGTGTCTTGGGGCTGACACTTACA TGGAATTCCGTGGTGTTGAGAATGTGGCGCCCGTCCGGGCTCCAGCACGAGGCCACCAGC CCGGCTGAGCCCTCGTCTATTTTGCAGTGCCATTCGGGCTGCTCTAAAGACCAGACCTGG ATTGAGAGAAGAAAGAAACACACAAGTGCAAACTCATCAGCACCGAGAGACAGCGAGGAC AGCTCGCTTAAACGCAGCGGAGACCCGACCGCACAGGGTGTCTTCAAACTCATCAGCAGT CTATAGCGAGGCCTCGCCGAGAGACAACTCCCTTAAAACCAGCAGAGACCCGATCACACA GGGTGTCTTTTAGAACCTTTCATGATGAAGGGCTGGTGCTGGATTCCAGTGTAAAAGTAA GCCACGCTTCTTGGTGATTTCATTTCGTTGTTGTTTTAAAACTGTTTATTCACATTGTCA TTCCTAAGACCTCATTTAGTTAAGCTTTGGACACAGAAGAAAACACGACTTCTTAGGACT TCCTGAAACACACCACATCCGCGTGGCTAGATTGCTGTCAACACCTCCGTTTCTCAACTA TATTGCTTAGAAATTAAGACTACGTTGGAGTTTCCTTAGTTTAAATGTTCTTAAACTTTA GAGAACGTTATAATTTCAAAAGAAAACTGGCTTTGAGCTGCACGGACTTTTTTTTCAAAC TAGAAAGGCACAGAACAAAACCCCTCCTTCCCAGGGGCCCTCAGAAGGTGTCCAGATTCT AAGCGACACGGCAGCACACACCTGCACCAGCCCTCGCTTGTACATGGCGCACAGGATGAA GAGCGAGTCTGCCGACCACTCGATGTGCTGGATCTGGTCTAGGCACGTGTACAGCTGAAG GATCTGAAGGGTGTTCACATCCCGGACCACTAACCGGTACTGGACACAGGAAGCCTAAAA AATATGAGAAAGCAAGCACCTGACATTCTCCACTCCAAAAGAGGGGGGCCTTCGGAATGC TACTGCCCTGGCCTTCAGTGACTGTGGCCTTCTCTCCTGCCAGAGGTTTCATGTCTAGAT CACCAGTGACATCCCCAGCCCCTAAAGATCAGTTCAGTTCATACAAGGGTAATGTTGAAA TATACAAGCCAGGTTTTAATATTGCTATACTCTATTGTAAAGTATAAAAGTATGTTTTAA CTCGCTACTTAAAGCTTTAAGACATTTTTAAGTCCCTTCTTATCTGTATGTTAAAAACTA AACTTAAATGGGAAGTAGCATTGGGAGAAAGCTCTTCTGTGAACTAATAACCAAAATCCT CTGCTAGTTTTATAAACACTTTTGGACAATTTCCTCAAATTTATAAAGGGTAAGAATTGA GGCTTCACAGATGACAACGAAAATGGCAAGGAATGCATCAATCTTCTTATGCAGTGCCGA ACTCAGAGCCAAAACAACAGAAGATCAAAAGACAGGCTTTCACTTCTGCACACATAAAGA TGCTTCGCAAATGCTCATTTATCTCCATTAACCTATTCCTAACACGAAACGGGAAATGTT TAAGTGTTAGTACTATTTTCTTAAAGATAGTTTCTTCTTGTCCATATTTGTTCATTATGT CCCTATCCAAGCAAACAATTTCAAGTAAAAATAACGCCTGAGTACTCACCTGCTGAATGT ATATTTTACTACAGTTTCAAGATCAAGAACTGATGTTTAAATATTAACTGCTTCGTTAGT TTTACTTATCAAGGTCAAAGTAGTTTGTGTTTTATGAACCGATATCAAAAAAGAAAGCCA CGTTAGTTTTCCGTGGGAGAAAAGAGAGACAGGCGGGTGACGGCAGATTGGAACAAGGAG CTACCACAGCACTTACTTTCTCACACTGTAGCTTTGAAAACTGTGATCAGTTACAGTGAA TTCCTTATGAAATGGAATATTTTTACCAACACCTTGAGGAACCACATAAACTCTACTGCA AGATATGAAAACTAGAAACATGGACCTGCTCTCCCCAGTCCTCAGGGCTTTCAAGAAGAT GATTCCAGTAACAGATCATTACCAAGTGTTTCAGGGTATTTTGACCAGAGTGTACAAGCT GGAAAAAAACACCCAAGTTAAGCAAGCAGATGTAATCTTTCTCCTTATAATTCACTGAAA TTTTCATAAATGGTAAAAACAAAAAACAAACCTCTCATTTAATTGAGGAGGGGGGCACAT TGAAAATATACCAAGGCTGAGATGCCATTTAAACTAATGAGGTTTTCTGTTTTGTAGCTG ATGCTATTTTATGTGATTTGGAATAAAACCTCCCTGAAGAGGTAAAAAACGTAATTTGAG AGTTAAACTCTCAAAAGCTAGACAGAGCACAGGAATGTCAGGAGTGGCAAAACCTGAAAA AGCATCATGATACATCAGTCAGTTAGTACAGGTGGTGGATAAGGAAAACGAAGCCCACTT TTTACGAGGCATGTTTCTTCTTAGTGGCTTTCCAATGCCAATTGTCCCCCTCTTCTGAGG ACATACATACTAGGCATCCGGGTTATCCCTCTCTTCTGAGGATATACACTACTAGGCATC CAGGTACATACACTATATGTTTTGAAGCTTAAAGTTATAGCTCTGTGATTTAAGCACCCT TCTGCCACCCATGGAACGAAGACCTCAAATCCCAGCCATGAGGACAACTACTTCCTTACC TGGGGATAGAATACTAGTATTTAAATCATTTATTCGGCATGTGGTAGAGGAGAAGAGAAT TAGAGGAGAAGTAGAGATGACAAAGTAGCCACACCACTTACCAGTTTACAGGCAACAGAA TCATCAATTTGCCTTTTGTGACAAAGTAACAACAAAGAGCCGACATCTCCTATACCCTCA CCTGTGTGCAGTCGGCACTGCCGATACCCACCTTTCCAAGGGCACCTCCCCAGACCCCCC ACCTGTCTACGGTATCTTCCTGGGTCCCGCACCTGCCCGGGCACCTGCCGGGGTCCTGCA CCTGTCCGGCCCCCATATCTGCTTGGGGTACCTGCCTGGGCCCCGCACCTGCTTGGGGTA CCTGCCTGGGCCCCGCACCTGCTTGGGGCACCTCCCCGGGCCCTCCACCTGTCTAGGGTA TCTTCCTGGGTCCCGCACCTGTCTGGGGCACTTGCTCAGACACTGCACCTGCCCCGGGTA CCTGCCCGGGCCCCGCACCTGTCCGGGCACCGCACCTGCAGGATCCCCAAGCTGCCTCCA CCCACGCGGCCGCCCCCGGCCCTGCCCGCCGGGGACGCTGGCACCGAGGATGTCCTGCCC GTGGCCCAGGTCCCCGCCGCTCACCAGGTACTTGCCGTCCGGGGAGAACTTGCAGAGTAA GCTGGAGAGCTTGAATACCTCGGAGAAGTTCATGGCCGCCGCCTGCCGCGGGCGCCACCC TGCGCCCGAAAACCCGCGGGACCCCTGGGCGCGCAGCAGGCTGCAACAGCCGACGCCGGC CTCCGAGGCCGGAAGTCAGAAGGCGGAAGTGAACTGCAGCCTATCAGCGCCGCCGGCTTC CGCGCGGCATTGTGGGGCTTGTAGTTCTTGTGCCGCAGGGCTTTAAAGGAAACGCCCACG TTTCTTCCGACCAGGGATTTCCGACCCGAGAACCTTACCTCAAAGGCCGGGAGGCCTTTG AGCACCTCCAGCTAGGGCTGCTGATAAAAATGTAGAAAGCACAGTAAAATTTGAATTTCA GATTCACAACAAATCTAGTTATAAGTATGTTCCCAAATATTGCACGGGACATGCTAATAC GGAAAAATTACTCGCTAGTCTGAAATTCAAATTTAATTGAGCGACCTGTGTGTCTGCGTG TGTGTACACATGCATATATATATATTTATATTTATATGTAAATGTATGTTTACATGTAAA TATATGTTTACCTACAAATATATCTTTAATAAGTAATACGGTGTCTGTCGCACATATATT ATATCGTGTATGTAATGTATAAGTATTTATTTCGTTTGCTTGGGGTTTTGTTTGCTTTTG CTGAGTCCGACCCCTCTACCTGCCGCCTGGCCCTTGCCTCACGCTCCAGTGCCACTGAGA TCAAGGAGAGAACGAATTTGCCGCTGACTGGGCAGAGCGAGCGCGTGGATCGCGGCCACC GCCCGTTCATCACCCGCGCGCATCTGGGCTGGCACCGGGCGAAGAATCGTGCGGGTCTGG GACCTGGGGGCCCAGAGGGAGCGAGCTCCTGCGCGGGCGCTCGGTCCGCAGGTTTCGCAG GCTCAGGGGCGTGCCTCGTTCTCACCCCCACTCCGGACCCCGGTCCTCTTCCCTAGACAG CGGCCCCCTCCACCCCTGGCTCCCGCAGGCCGCTAGTAGTCCGCGCCAGGCCCCGCCGGC GCCTCTAGGGCCCCCCAGATCGCGCAGACCCTGACATCCCCGCCTGGCCCTGGGTTCTGG GAGCTGAGAGCCGGCCAGGGTCCTGCTCGTACCTCCGGGCGCCCAGCCTCGGGTCTGCTC CCCGCGGACGCCCCAACCTCCCCGGCCGAATGGATGGTGGTGCGCGCGCGTCCTACTCCG GCGGTGCCGGCCTTTTCTGTTGCCAAAACTAGACCCAAACCTCTGCATGGGATTCGTCTT TGGGTCCCCACCCCGTGCGCCCAGCAAACAGTGGGTGAGCCATGAAGATGTGCGAGTCAG CCGGACCCTCCCCGTCAGGCGCGGACCCGCTGCGGCCAGAGAACCCAGTCTGCGCCAGCC CGGCTCGCTCGCGAAGCCACGGGCTTCACTGACGCGACTTTCCAAGACGTGGGGGTCACC ATGGGCAGAGGACATCGGTTCGGAGCCAGATCACGGGCCCCATAAGCATCAGACCATAAG CAGCGCCGCCACTGAGAGCCGCTCGGAACTCGCCCAGCATGTCGGGTCCCCTAGCCAGGG CCTGGTGTACGTGGTCGAGGGCCCTGGAAGCCCCGATGGCCTAGGAGGAGCAGGCGGGCG GGGCGGCGGGTGTCGCTGGCCGGTAGAGAGCTTCGGCCTGACCTAGCGCAGGTCTGGTGC GCGCAGAGAACAACTCCAAGCGCACCGACGCCCGCGAGCTCCTTCCAAACACCGAACGGG ATCCAGAGCCCGAGCCCACAGGCGGCGGCCGGGGGAGGGAGCAGGGTGCTGGCCGCCGCC CGGGAGTGTTCGCGTCCTGGGTGACCCCTGGAAGGACGTGGGGCCCAAACTCCGGCTGGG GTTGGGAGAGCAGCCCCCAGAGGCTCTCCGCGGGATCCTCTGCCGGGCGGGACCGTGGCT CCACAGGAGAAGTGGGTGGCAAGCCCTGCTTGGCGGAAAGCAGCCGTTCCCCTCCTCCTG GGCCTGGGGCGGCGCCCCTCACCCCTGTTCCCCGCCCCTCACCCCTGTTCCCCGCCGGCC ACATCCCCTGCCCCTTGGATTCCAAGCGCCCCGCGCGCCGAGGAGCCCAGCGCTAGTGGC GGCGGCCAGGAGAGACCCGGGTGTCAGGAAAGATGGGCCGTCTGGGGGACAGCAGGGAGT CCGGGGGAAACGCAGGCGTCGGGCACAGAGTCGGCACCGGCGTCCCCAGCTCTGCCGAAG ATCGCGGTCGGGTCTGGCCCGCGGGAGGGGCCCTGGCGCCGGACCTGCTTCGGCCCTGCG TGGGCGGCCTCGCCGGGCTCTGCAGGAGCGACGCGCGCCAAAAGGCGGCGGGAAGGAGGC GGGGCAGAGCGCGCCCGGGACCCCGACTTGGACGCGGCCAGCTGGAGAGGCGGAGCGCCG GGAGGAGACCTTGGCCCCGCCGCGACTCGGTGGCCCGCGCTGCCTTCCCGCGCGCCGGGC TAAAAAGGCGCTAACGCCCGCGGCCGCCTACTCCCCGCGGCGCCTCCCCTCCCCGCGCCC ATATAACCCGCCTAGGGGCCGGGCAGCCCGCCCTGCCTCCCCGCCCGCGCACCCGCCCGG AGGCTCGCGCGCCCGCGAAGGGGACGCAGCGAAACCGGGGCCCGCGCCAGGCCAGCCGGG ACGGACGCCGATGCCCGGGGCTGCGACGGCTGCAGGTAGGAGGCCCAGGGCCGGGGGGCG GTTCGGCTCCGCGGGCGGGGGCTGGAGCGCAGCGCTGGGCAGGCACCTGGGCTCGCAGCT CCGAAGCTGGGAGGTGAGGGGAGAGCGATCGGGGA bcftools-1.21/test/csq/ENST00000378322/ENST00000378322.fa.fai000066400000000000000000000000211467060157400215320ustar00rootroot000000000000001 21995 21 60 61 bcftools-1.21/test/csq/ENST00000378322/ENST00000378322.gff000066400000000000000000000073761467060157400211740ustar00rootroot000000000000001 ensembl_havana gene 1 21995 . - . ID=gene:ENSG00000116213;Name=WRAP73;biotype=protein_coding;description=WD repeat containing%2C antisense to TP73 [Source:HGNC Symbol%3BAcc:12759];gene_id=ENSG00000116213;logic_name=ensembl_havana_gene;version=11 1 ensembl_havana transcript 1 19292 . - . ID=transcript:ENST00000378322;Parent=gene:ENSG00000116213;Name=WRAP73-002;biotype=protein_coding;havana_transcript=OTTHUMT00000001471;havana_version=1;tag=basic;transcript_id=ENST00000378322;version=3 1 havana three_prime_UTR 1 631 . - . Parent=transcript:ENST00000378322 1 havana exon 1 891 . - . Parent=transcript:ENST00000378322;Name=ENSE00001755234;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001755234;rank=11;version=2 1 havana CDS 632 891 . - 2 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 1447 1572 . - . Parent=transcript:ENST00000378322;Name=ENSE00003534355;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003534355;rank=10;version=1 1 havana CDS 1447 1572 . - 2 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 2632 2737 . - . Parent=transcript:ENST00000378322;Name=ENSE00001659258;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001659258;rank=9;version=1 1 havana CDS 2632 2737 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 4231 4308 . - . Parent=transcript:ENST00000378322;Name=ENSE00003685083;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003685083;rank=8;version=1 1 havana CDS 4231 4308 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 4394 4528 . - . Parent=transcript:ENST00000378322;Name=ENSE00003492457;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003492457;rank=7;version=1 1 havana CDS 4394 4528 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 5178 5264 . - . Parent=transcript:ENST00000378322;Name=ENSE00003480267;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003480267;rank=6;version=1 1 havana CDS 5178 5264 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 6229 6332 . - . Parent=transcript:ENST00000378322;Name=ENSE00000734306;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000734306;rank=5;version=1 1 havana CDS 6229 6332 . - 2 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 7984 8056 . - . Parent=transcript:ENST00000378322;Name=ENSE00000734303;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00000734303;rank=4;version=2 1 havana CDS 7984 8056 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 15900 16016 . - . Parent=transcript:ENST00000378322;Name=ENSE00000734299;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00000734299;rank=3;version=1 1 havana CDS 15900 16016 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 16642 16794 . - . Parent=transcript:ENST00000378322;Name=ENSE00003566716;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003566716;rank=2;version=1 1 havana CDS 16642 16794 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana CDS 19165 19233 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 1 havana exon 19165 19292 . - . Parent=transcript:ENST00000378322;Name=ENSE00001870155;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001870155;rank=1;version=1 1 havana five_prime_UTR 19234 19292 . - . Parent=transcript:ENST00000378322 bcftools-1.21/test/csq/ENST00000378322/ascii-art.txt000066400000000000000000000004071467060157400212670ustar00rootroot00000000000000 exon 19165 19292 cds 19165 19233 5'utr 19234 19292 19295 xxxx CGCGCAGCAGGCTG A-------- bcftools-1.21/test/csq/ENST00000378322/ascii-art.txt-l000066400000000000000000000004071467060157400215200ustar00rootroot00000000000000 exon 19165 19292 cds 19165 19233 5'utr 19234 19292 19295 xxxx CGCGCAGCAGGCTG A-------- bcftools-1.21/test/csq/ENST00000378322/end-overlap-tscript.txt000066400000000000000000000004731467060157400233200ustar00rootroot000000000000001502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C 1502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C 19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding 19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding 19295 AGCAGGCTG A . 19295 AGCAGGCTG A . bcftools-1.21/test/csq/ENST00000378322/end-overlap-tscript.txt-l000066400000000000000000000004731467060157400235510ustar00rootroot000000000000001502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C 1502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C 19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding 19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding 19295 AGCAGGCTG A . 19295 AGCAGGCTG A . bcftools-1.21/test/csq/ENST00000378322/end-overlap-tscript.vcf000066400000000000000000000007321467060157400232550ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1502 . G C . . EXP=missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C 1 19291 . G A . . EXP=5_prime_utr|WRAP73|ENST00000378322|protein_coding;type=no splice 1 19295 . AGCAGGCTG A . . EXP=.;type=ENST00000378322:3566625-AGCAGGCTG-A beyond; bcftools-1.21/test/csq/ENST00000379416/000077500000000000000000000000001467060157400166565ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000379416/ENST00000379416.fa000066400000000000000000002377371467060157400210400ustar00rootroot00000000000000>2 2:31334222-31414742 TGTGTGTGTGTGTGTTTTCAAGAAATGAAGGCTGGCCAAGATACTGAAGATACTAGCATT TGGTGTGATGATAATTAATAAGCATTTTTCACACGCCAACCAGCTGACAGTTTCATTTAT TAGTGACATCAAGCACCAGTCCAACTATATCATTTCCACTATCCTCCCTCCATGGCCAGA ACCACAGATTCTCTCTGGCAGAAGGTTGGATTTATACAGTGAAGGCATGTGACAGTGACA CATTGTCCACCCAGCACCATGTAGGGATTAAATCACCATTTGGAGCAATAAAAGGGATGT TTGTTCTTCCCTTGTTCTCTTTACCAACCGCAGAAACTTGAGGTGATCTCAGCAGAGTTC ATTAGACCCAGGTATCATATGACAGTAAGAAAACCAAGCCTTAGATAGCTGCAGATCCTT TATGTAACTGGAGTTTTCAGGTCATATATTTATAGGCTTTTAAAGCAGAAGACGTGAGAC AACCCTTTACTGCAACCCTTATGTTTGCAGTAAAATGGATCACAGGAAGGGGAATTGACA GTCCAAGATCACAAAGATAGAGACAGAAGAGACAGAGCTAGGATGAGAACCCAGGCTTCT TGGCTCTTCTACCTCTGGTTGGGCTTGATTTTGATAGCAGCATTTTTATTTCTTTTTTTT TCTTCAGAGACAAGATCTTGCTCAGTCGCTCAGGCAGGAGTGCAGTGGCGCAATCATAGC TCACTGCAGCCTCAACCTCCTGAGCTCAAATGATCTCTCCACCTCAGCCTTTCAAGTAGT TGGGACTACAGGCATGCACTATCAAGACCAACTAATTAAAAAAATTTTTTTTAAAGACAG GAGCTCTCTATGTTGCCCAGGCTGGTCTCAAACTGCTGGGCTCAAGCAATTCTCCTGCCT TAGCCTCCCAAAGTGCTGGGATTATAGGGGTGAGCCACCATGCCAGGACTGATAGCATCA TTTCTAGGTGGAAATTACTTTGGCTTCAAATGTAAAGATTAAACATAATCTTTTTTGTAA ATACTCAAAGAGTATTTGGAATACAAATATTCTCTTCAAAGAGGAAGGGAAAGAAATCTA GAACATTGTACGTGCTCAATAATTGAGTTGGTTGGATTTTTGTATTATAGAGTAATCTTG CTTTATGCAGCTTCACAAAATCAGATCCAATTAACCTTGAATTTGTTTCATTCTTTATTC TTTCCAATGATTCAAAGATGGTTAGAGGATTTAACCTTACCCCACTGCCTCATTGCAAAA TTTGAGTATAGATTCAAGGTTATGCTTTGCTGTTCATTGGTTTGAAGGCCAGGCTTTCAC AGGAAGGCACACGATTTAAAGTAACTTCGGTTTAAGCTTCTAGAGGTTTGTGGGAATCCT CTTCAAAGGACAGACACCATCAGAACTTGAGGTTATACAGGCTGTCCAGTAAGTGGGGAA TAGCACAAACCCTTCCCGACCCTATTCCAGATACATGATTAAAACAGACAGAAAATGATC CTAATTGCATATTCACCATTTAGGCATAACAGTTTTGAATTTGCTTATCATTGTGTTTAC AAATTACATTTTTGATCAAAATCTTCCATTGCATTCACTTGTCTTCCAAATCCCATCTTG ACAAATCACAGGTCTGTCATTCTGTGACTTTAATAGATCCATGTTCTGTGGTATGTTCCT CCTGCTCCATGGAAGCCCAAAGGCAGCACAAGAAGACTCTGCTGAGGACTCTCTCTTTAG ACCCTCACAGACCAGGGTTTGCAGTTTTCTGGGACACCAGTGACACACTAGGAAGGAATG ATAGTGTTCTCATTGCCAGGGTCTGCTGATCATGCTCCTCCCACTCTCTTGCATACCTCA CCTCCCACCACTGCCAACCATCATTCCAAGGCCAAGCACCACTCTGCAGGCCTAGCTGTT GAGAATGCCTCAGGGCAGGACTCCTTAATTTCCTAAGCCATTCATTTATTTTCACTGAGC ACTTTCCACATGGCAGGCGTTCTATTAGGTTTTGGAGATATGGTGACAAACAATACAGAT GTGATCCCTTTTGAAACTCACAGTCCTTAAAAAGTTCATAGAATCAGCTGCTCATGCAAA TCCATGGCAAGAATTTTTAAATCGCTGGTATGTTGTAACATAGAAACGGATCTTTGTTTC AGGTCTGGGGCCACAGAGAGCTTACGAAAATGACTGAGTTCTGCATCAGACTGTTGGCAA AGAGCTCGCCTTGCAAACTGTGGCAGCTTATTGGGAGCCATGCCACCCACTCCTCTCAGG GAAATGGGTTTGGGTGATTGTCAGCATTGGGAGCCATAGTGGGAAGGTTCTGGGCTGTGG GTAGGTTGCTGCACAGATGTGGGCATCTTTACTGCCTGGGAGTGCCACACGGTCTGTGTA GTTCTCACTCCATAGCTAAAGCTCTTGGTAGACCCAAGGAAGACCTGAATGGGGACCCAT ATGCCTCCTTCACCCACTGTGTTGAGGTCTGCGGATGGTGGATTTGTCTGCCCCTGGGGT TCCTCTGTGCCCTCCCCACTTGGGACCACATGTACCCACTTTACCTATAAATCCAAAAAG CATATCGAATTTTAAAAAGAGAAAGCCCCACCTGAGTATCAGGAAGAACCCAGTCCTGCT AACTCCACACAGGTTGCAGTTGCAAAGGCAATTAAAGCCACTGTACAGAGCCCACTTCAG CACCACTCAGAGGCTGGGCTGGTTCTGAGATCCCCAAAGCGGAAGCAACCGTCCTAGCAA AGTCTTCTTTTGTTAGGCATTGCCAACTACAAGTATCACATAGGTGCTTCTTAAAGTGAT TCCAATGACTACGGAATTCTTCTACTACTTTCTGCCACATACACCTCCAAGGCAGTAATC AATCACCCTATAATGGAATCATCTGGTTTCCCAAGGTTGCAAAGTCCTCAAGGACATCTA TGTGTCCCCAGTATCAGAATGGCACATGATCATCACAGGACAAATGTGGTTGATCTAATT AATTATTTCCTCTTTTTCCCTCCATCCCCCCAATATTCATACAGTGTCCTTAACATAAAT TAAAAAAAAAAATGCTAGCGACTGACTCATACTAAAGATTAGGCTCTCTGGAGTTTCATC CATCATCCTTATCTAGATGGAAAATAATAAAATCTGTGAGTTATGACTGTGCACCACACA TTCCTCCCATCTCTAAGGAGGCCCAGCTACAAGCTATAGCTTTAAGGAGGTTTCTCATTA TTCTCTTGCAAGTTCGAGTGTGTGCTTCATACCATGCACAATGAAGGGTGGCCATTGATG CAAGGCTGCCCGGTTAGGAGAGAGCCCAACACCTCTCCTCTGTGCAGAACCTTCCCTGCA GTTTGCCAGCCTATCCCTGGCCTCCCCTGGACTGAGTGGATGCTTGAGGGGCATCATACC AGGGTGGTGAACTTGTCCACGCAGGCATTGCGGATCTTCTCCGGGGTGGCAGGGCTGTCT AGCCGGAAGAGTTCCTTCACGTTATTACCTGTGTGCTGAGCTCGAGCTGCACGGATGGCA TCTTTGATGGCAAAGAAGATAGAAGCAGCCAGGAAGAGGGGCGGCTCTCCAACAGCCTGA ACACAGACAGGGCACAGGGCAGGGGCTCAGGCAGGTGGTCCTGCCTCCACATCATCAAGT GGACCTAGGAGGCCAGGCAGCAAACTCTGCACGAGGAGGGCTGGTGGCACCAGGAAAGCA CTGATGGGAGCCACACCAAATACAGCAGGAAGGCACAGTCAGAAATGATCAGGGGCTAAG AACAATCAAGCTAGTACATGACTGGACCGCATGGACATATTTCTTTGAACACTCATGTAA TTTTCTCTGATGACATCATGCACATATAATGTACCATTTAAAGTTATACTCGGTAATTGT ATTTTACAGACCACAAAATCTGACGTGAGTTTTAACCTTTTCCTCAGTCACTAGCCGAGG GGAAGAGTCTACCTGCAACTCTGACACCAACATTTACAGGCACCATAGTCATATTACAGC ATCCGCAGGAATTATAGGCATAAGAACAAACAGGAATTAAAACATTTTCTAGCATAGGTT GGTTTTTCTCCCCCTCAAAGTATAGATCAGAGACCACCTATATCAGAATCACTAAAGATA CTTGCTGAAAATGCATGTTCCAGGGCCCTAAGCCACACCTATTGGAGCAAAATTTCTAGG CGTGGGCCCCAGAAAGGCACATTTTTATCATGGGCCTCAGTAATTCCCAAGCATGGTAAA GTATGACAGTCAATGGCAAGGGTCACAATATGTCCCAGCTTCCCCACCCACTATGGTAAA GTAAACCACGAGATGAGCAAATGGATGTTTCTTTGGTTACCAAGGATTAGTTGCCTTCCT TCTTCAAACTAGGATTATATGCATCAGCTAAATCAATTTTCAACCATTTTTTCATACTTA CTGCAGATAAGGAAGAAATAGAAGACACAATCCTCCAGGCATCTGACCAAGTCTTTTTTT TTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGGGTGCAAT GGTCCAGTCACGGCTCACTGCAGCCTCTGCCTCCCAGGTTCAAAAGATTCTCGTGCCTAA GCCTCCTGAGTAGCTGGGATTACAGGCATGTCCCACCATGCCCAGCTAATTTTTTTTATT TTTAGTAGAGATGGGGTTTTGCCATGTTGCCCAGGCTGGTCTCGAACTTCTGAGCTCAGG CAATCCACCCACCTAGGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCGCACCCA GCCTGATCAAGTCTTAAGGTCGAGTATTGGCAACTGAAGGAGGTAAAAGGGTGTGTACAA AGGTGCTATCCCATTGGCAGTGAATGTGCTGATTGTCATTGGACCATACTAATGCTGTAC CTGTAAAATCATCTCTTAGGATCAAGCACCAGTGACGTACGCCTGAGATATGGGTGTGGG CCAGGATTTAAATGAGAAGATTTGATGAAGGAATCCCTCTAAATTCACCCAAAGAAGTGG GCTTCAGACCATACTAAGGTGCTCTCCTCAACCCAATTTAACTGGTTCTCAAGCAGGACT GCCCAACTATCCCACTGCCCCTACCAAGGTCAGTGTCAAACCATCTTCCCTCCTCAAGAT ATGCCCTTTGAAGTCCCACCAGGTGGGTCACTGAGGCCTCTCATCACCCGCTGGGGCCTC CCCCAGGGCAGATCAGAAGAGACAGCACAGAGCCAGAGCAATGGTACCTTCGATGCATAG ATGGCCTTCTTGTTGGGGCAGTCGCGGAGCAGGGACACCCTGAACTCAATGGGGATGCTG CCAAATGCCGGGATCTTGTAGGTGCTAGGGCCACGGGTGTGCAGGCTCCCCTCGGGGGAA TAGTGTAGCTCCTCTAGGGTGAAGAGGCCAAGGCCCTGGACAAATGCCCCTTCCACCTGC AGGATGGATGGAGAGCACAGTTAGCCTGCCACCTTCTTCCCTGAGGACAGATACCACTTG CCACAATGGACACAAAGCGCCAACTGCAGCGCGGCCTGGAATGTAGCTAAAACTGCCCTC TATTGCTTACCTGGCTCCCGCCTCAGCCCTGGGATAACCCATCCGGACTTCTGCCAGGCT TTGGCTCAGGCAGAGCAAAGACATTAACACGGAAGGTCAGTGATTCTAGGTGGGCATGTT TCCCACTACAACCTGCCGCAGTGCAGATGGAGATGTTCCTTCCATGTTGCTACTGGGGAA ATGGTGAGCCAAAGCTAAGAAGCAAGCTCACAGGAGGATTTATTCGATAGTAGATTCTTT GAGACTTACCTCCAGCCTTTTTGAACGCCCACCCCTGCCTGTCCTCTGGGAGAAAGTGCC CCCACTGCAGTTCAGCTTACAGGTCTCTCCTAGGGTAACTGCCATGATAGACAGGCCCAC ACATCTGCTCTCTCAGCCCCCTGCTCAGAAGCGTGACATGGGGCACTACCATACCTCAAC GAGCATTCAGAAAAGAAACCGACTGGCAATCATCTTTGGGTCTGCAGTACTGGCTTGGTG CCTGGCCACAGTAGGGGACCATAAATGGTTGTTCAATGAATTAATGAACAGATTGACTAA TGGCCAGATTTTCGTATACTCAGTAGTTGTCCATTTTTTAGAAGTACAATTTGTATTTTC TACCAGATGCTCAGTCTTGAATTCTTGATTCCTCCTCTGTTTTTTCCTATCTCACCTATT CTTTATTTTATTTTATTTATTTTTTTGAGACTGAGTCTTGCTCTATCGCCCAGGCTGGAG TACAGTGGTGGGATCTTGGCTCCCTGCAAACTCCACCTCCCAGGTTCAAGCAATTCTCCT ACCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCATGCCACCACACCCAGCTAATTTTT GTATTTTTAATAGAGACGGAGTTTCGCCATGTTGTCCAAGCTGGTCTCGAACTCCTGATC TCAGGTGATCTGCCTGCCTCGGCCTCCCAGAGTGCTGGGATTACAGGTGTGAGCCACAGG TCCCAGCCCTATTTCACCTATTCTTCATAGTAATCCCATATTCTCCTAAAGCGATTTTCT CTGGGACCTCCCTTTACTACTTCTGCTTAAGCCTTTGTGTTTTGCTCCCAGGGCCTTCCA CCACTCCATGTTTGGCAGCATCTGCTTCCTGGGGTACAAAAGCTGTCCTAGGTGGAGGAG GAATGAGAAGACAGAAAACTCTTCTGACCTCAGACCCCACTGTCTGGGCATTGATCCCAA ACTCAATCCCCATTCTACGTTGTGCTCACACTCAAATTGGGTGTGTGTGCATGTTCACAT GTGCATGCCATGTTTCCTCATTTCTCATCTTGTTTTTGAGTTGTGAGTGCCCTTCCCAAG TTGACCCATATTAATTTGCTTTCTGCCTTGAGGGTTGGTTGGACTATCACCAATCTAAAT TCTACTTTGGGGGAAACTCCCTAGGTTCCATGTTTCAGCCTGTTTGAAGACAACCTTGGA CAACATGTTGTGGCAGGTGGCCCCAGGAGGGGAATGGGGTGCATCGGTGGCCAAGTCTGT CACCACCCTGGTCCCACTGAGCCTCACCTGTCCAATATCAATGGCAGGGTTTAGACTGGA GCCAACATCCATGACAATATCTGTGCGGAGGTTCTAGAGTAGACAGCAAAATTACAAGAA GTTAGAGGAGGAAAAGATGTTTGGAATATGACAGATGACTCATAGTGACCCTCAGACTAC AAGTGCCAACCAAAGAGTACGTTCCCAAGCAGAAAGCCCTGGGTGTGCTCAGGCAGAAGT GTTGATGTTCCCACCAAATCTCTGCTGCCACCATCCCCGCTGGAGTCTGAGTTTGTAGCA GCCGGGTAGGAAGTGGGGAGCAGCAATGATCTCTCAGTAACTGGGAATAACACACATTCA TACGTGAGTAGTCAGATAGGGTCCCAGAAACCTGGGGCTTTGAATCTGAGTCTGGGTAGA TCATGTACAAAAGAGTCAATATACTACGTTCCATGGGCTAAATCCAACTTGCCCCTGTTT TCGTGGGGCCTGTAGGCTAATAATTACATTATTAAATAACTGGAAAAATAAAAAGAAGAA TATTTTGTGACAAGTAAAAATTGTATGAGATTCAATTCAAATTCAAATTTCAGTGTCTAT AAATCATATTTTATTGGAACAGAGTCACACTTATCTGTTTACAAGCTGTCTATGACTGCT GTCACACTTCAATGGTAGAGTTCAGTAGCTGAGGCAGAGACTGTATGGCCCACGAAGTCT AAAACACTTACTCTGTGGCCCTTTATAGGATGTTTGCCTATCCTTAATGGAAGGCATTAT TTTTCCAACCAGAAATCTTGTCTCTATCAGCTCTAGGTATTACAACTCAGTTGTTTCTCT TCTCTTTCCCACTAAGTACTAAAGTTTTGCAAACTTCTTACCTTATGATCTCCTGTTAGG CAGTCGATTTCTACTTCAGAGCAAGCCACCCCATAGCTGAAGTAGTGGAAGGGGTTCCCT GAGTTAGTCTCAAAGCTGTAGCCCAGATTGGGTGTTCTGGGAGAGGAAAGAGAAGGTACT GCACATGTATTAACATGAACACACCCCCTTCCCTATGCACGTACAGCTTGACCCACAACA TCTTTAAACCCCACAAGTTTTTGCATTCAGCTGTTCTCCAAAAAAGTCCATGGTTTGAAC AATTTGAACCTGTTAACGAAACCCAGATATTCCAGAACATTTTGTCTCTGGGCCCTCCTC TATTTTGCCAGTAGCCCTTCTGTACTCATTCTGTACAGCCTAGCAGTGTTTAGTACCATG CTAGCCTCTGCACAGTAGAAAGAGAGGTAACAGATCCATCTGGGCTCACGAAGGACATGA AAGTCACACTCCAAAGGATGTACTGAATTAGAATCCAAGGTCTTCAGGACTGAAGGTTCT GCCTGTGGTGGCTCTTAGACTGTTCACACAGTTCTCCTGCTTACCTTCTCAAGGTGAGAA AGTTAATAAGATCAGCATCTCATGCTAACCTGGGTGCATCTTTAAGCGGCCACTCCCCAC CTGCTGGTCCCTTTGAAAGTTCAACAAATGATTTGAGGGAAATGATACGAATAGAAACAA ATGCTCCCTTATACATTTTTAAAATTTTCAATCTGGAGTACCTTATACAATTCCACTTTT GCCTGAGTCATATAAATATATGTGTATATCTATGCATTTGTGCATGTGTATTCACACACC TAGAGTTTACAGTACACTGACTCTGTGTTATTCTATACACTACACAGGAATAACATGAGC TGATATGACCAGATCTGCACAAAAACAAAACCAATATGGGGCTGAGGGAAAAGGCTTCTC CCAGAAAAAACCACCACCAATTCCTTTGACCTCTGCTTTCACCATGCTCCTCTGCTTTGA CCTTTATAAAACCTTAGTTTCATGAACTCCAGAAATGTAATAGGAATTTATGAGAAAATG TGTTTATGTATGTGTAGGTCAGATATTAAAAACCTAGAAAGCATTGGCAAAACATTTCTT CACCATATATATATATATATATATATATATATATATATATATATATGCATGTTTATACAT ATATATGCCTTATACATATATATTCAATGTAATATCTATACATATATATGAGCCACATAT ATGTTCATATATGGCATAGAAATGTTTTTTTGTGTATATATGTTTATACATATATGCCTT ATACATATATGTATAATACATATATATGCCTTATATACTTATATATATGTATATAAAGCA TACATATATGTATAAGGCATATATATATGCCTTATATAAGGCATATATATATTCAGTGTA ATATCTATACATATATTAGCCATATGTATGTTCATATATATGGCATAGAAATGTTTTGTG TGTGTACATATGTTTATACAGATATATGTCTTATACATATATGTATAAGGCATATATATT CAGTGTAATATCTATACATATATATTAGCCATATATATGTTCATATATAGGGCATATAAA TGTTTTTTGTGTGTATATATGTTTATGCCTTATATGTATAAACATATATATGCCTAACAT ATATATGTTCATATATATATTCATATACATACGGAAAATAAATGTTTCATACAAAGAAAT GTTTATACATATATATATTTATGCATCTATATATTCATACATTCAGACATGATATTTTAA AGAAACATTGAATTATTTTCCAAATATATTGAAAGAAAATATTCCAAATATCTGTGAAAG AAAAGGTCCTAGCTAAACTTCCCAGAGACGGCTAAAATATGATGACTGACAGTAAATATG ATCATATCTTTTTACAGCTGCTAAGTCAGATGGGCAGGGTCTCTAGCTATTCACGCTGCT ACTAAATTTAAAGTTGCAGAAGTCATACGCTCTCTTGAAAATCTCCCTGTATTAATAAGT TTCCACTGTATTCTGCATTTTGTAATAAGACCACGTGCTCTAAATCCTCCTCTCATTCTA TAAAAAAGTCCCACACACAGTACAAAGAAGGATGCATAGCTAACAGCAATGCCTAACTCA TAACACTACACAGCCTGGTTTCTGCAGGAGAACACTGAGGGAGGAATGGTTAGGTACTGG CCCCAATACGTCACCCATGAGGAAACAGGGGAACAGGTTCAGCAGGACCACTGACTTCCT CTGGTGAAATTGTGCACCCTGAGACCAGAACTAGAAGTCGGGTCTTCTGACACACAGCTG GTGCTTTTACCCCTTGGCACACAGTGTGGCCATTCCACATATTTTAGAGCATCTTTAGAC TGAAATTAGCGGAAGTCTGTTGAAGAGATAAGTGGAGCTGCTCTCTCCTGACCACAGCCT GGCAGGATTCGGTGCTGGAGTGGACCAGTGAGGTTAGGACGACATCACACTATGAGCTGG GCAAGGACAACACCATACTTACCTATAAAACCCAGTGGCAGACAAGCTCACTGTGTCCAT GTAGGCAGCTGTGACCTGAGGAGAGGAGATGGCCATCAGGCAGGTGAAGTGAGGTTTTCA GGAACCCTGACCTGCCACTAAGCTTTCAGGAGCTCACCTCCTCTGGAAGCCAATCAACTC ATTTTACTAGTGACTCCCATTTCCATACCTTACCTTACATTGTCACTGGCACCACCTGCA CCAGGTCCTCATTATCTGAAGCCTGGAACACTGTAGTCACCTCTTAACTGGTCTTCCTCC CTTGAGTTGTCTCCCCAGCCCAGCCAGAGTGGCCATCTTAACATACCACACTGTGCATGT CACTACCCTACTCTAGAGCTTTCCACGGCTCCTTATTGCCTGTAGAGCAAATGCCTGATG TTAAGGACCACAGTCTCTCTGGCATTTTGCAGCACACGAGGGCCACCCCAGCCACACTCA AGAGCTAAATCTCTCTCAATTCTTCCATCTCCCACACCTCTGCACCTTTATTTATGTGGT TCCTCTTCTATATATGTGCAAATCCTTTTCTTCCCTCAACAACTACTCAAACTTGCCCTC CATTCTCCCCTCCTTGGTGAACTCTCCCTAACTGGCCATTATAAAAGCAACACGCTATAG CGCTCATGTGGTACTTCACATGTTCACCTTGTGCTTTTACATATGCTTTCCTGTTGATCA AACTATCCCTCCATCCTATCCCTTGGACTATATAATGTGCTTTTTTGGTATCCCCAAACA CTAGCACAGACTCAGATTTAAGTTGTACTTGATATAATTTATGCCTTCTTCATTAGCAGC CACCAAACGATTTACTGTGTCACACGCGCTATTTAGCACTTTGCATACATTATCTTACTT ATACTCACAACCCCAGAAAACCTATACTATTATTAGCCTCATTTTACAGATGAGGAAACT AAGGCTTGGAAAGACTTGGTCCTAAAACCTGCACTAGTCATTTAACATAATGTGCGTGTG CATGTGTGTGTGTGCACGCATGCTTGTGTGCGTTTGTGTGTGCGTGCACATGCGCATGTG TATGTATGTGTTGGTGACTGTGGTTCATTTATTGGGGTTATCTGTTTCCCAGGCACACTG GTCTACATGGCTGGTGGTTGAAGACAAAGCTCAGATCCACAGGTCAGATGATAGAACATT GTTGTCGGGACTGTTGTTAAAAACATTTAAACTGCCTGATAAATCCATGCTAAAACCCAA CTACCAAAATCAGGCTACTTTCATGTGCTATTGGTACACGTGGTATGGAGAGGTCATAGA AGGCATAGTAAGATGAGTGGGTCTGAGAAAAATGGCATGTTTTCTTTAAATCTATTGAGG AAGATTTCTAGTGAGCCGGTTTATGTGCAGTCACATTTGATGTGTTACTCTTCTGCCCAG TTCTACCACTCCAATACTGGGGAAGGATGCAGAGCTGCCATTAATATTTCCACTTGCTGG AGGAGCCACAGCCTCCCGCCTGCAAGAGACTCCCTTGCCCCTTCCCTCTGAGATTTCTGA CATTCAGGCCACTGGTCTAGAAGTCAGAGAATTGGGCTCATTCTTATCATAAGTGCTTGT TCTGTCATTCCCCAAATCACAGGAATGATAGAAGTCCTTGGGTGATGTTTTCTCCCCACG CTGTCACAGAGGGAATCTCAGTAGACTCAGACTCAAGAGATGGAGATTTGAGGAAAACCA GGCTCATCTGGGACAAGCGGGGTGTGGGAGCAGACCCACTGAGTCAAGACAATCCGATGA GGCATGTTCAGCAGGCACCCATCCTCTCAGGCTCAGGCAAAGAAAACCCTGATTCCCACA AGGCTGTCAAGATCCTGGATCAAAAACTTCCCTCAAATGACCTCCCTCAATGATGAAAGC TATAGAGAAAGGGACCCAGCCAGAATGAGCATTTATTCATCCTGTAAAATCACACAAACC ACCTCAACTTCTCTCTGCTGTTCTGACTAAAATATTGTCTCCTATTACTTGTTCGGATTC GGAACGGAGGCCCTGCTGTCAATTTCCCTCTCCTTTGCAAACGTGACTTGGATCAGCTCA GACTTACCCAGTCTTCCCAGGAGCCACTGGGATTCTTCTTCTTGTAGGGTTCCAGCCTTT TCAAGATGGTCTGACAAGCCGCCTAAAGTAAACACCCCCCACACCCCAGACACATCAGTC CTCTGCATTCTGTAGCCCAGGCAAAACCCGAGGGCCCCAGCAAGGCTACCTCCAAGCAAT GCTGTACCCAGGGTGCCACTCAAACAGCCTGGCCACCCACTCCAGAATGATCAAGGCCCA GGGTAGAATCGACAGGACCTGGCCAATAGGGCCACCACTAGTCCCTGCTTGGAGAGCACT TCCTGACTCAATTCTTAGGCTGACAGAGGGCGAAATGTTTGAGGGATCCCCAGAGAGGTG TCTTCTTCCCTCAAACTGCTTGTTTGATTATATCCCCCATATGGCAGAGGAGCCAGTGTG GCCAACCTGCCTCTATAATCAAATTTCAGCTTCAGCCCATTGTCCTATTGCTAGCTCCAG CACCAGGGAGTAATTCCAGAAGCCTCTGCTTTCCCTCGGTATCCTCATCTCCCCATCCTG CACTCATCCTTCCCAGCTTTGAGGGCAGTGATTATGATTCTTGGGCCTCTCTTTTAGCTT GAGGTTTGGAGAAACAGCATCCTCCTGGATAAGGGAGCCAGAGGCCTGGCCAGAGCCAAA GAGCCTGCAAGGAACCCTTCTAGCTCCCACCCAGGGAGACTCTCCAGGCCCACAGCTCTG GGCTGGCCCTCTGCTCTGCGGGATCCCATGGGCTCCTTACATAGACGGCCTGTCCATTGA GGTCAGCGCTGACAGAGGCAGCCGTGGGAGAGGTGTTGGGCACAGTGTTAGTGCTTGTCT CGCTGATATAAATCTTAGAGGTGGGGATTTTCAGAGCTCTACTGGCCACCTGCGAAAAGA GAAGACATTGCCCTCTAGGGAAGGGGTTATCATGGGGCTTGGCTGCCTTCTCCCCAAGAC AGGATTCACATTCACTGTTACAGGCAAGAAAACAATTTCGTAAACTCTAATCTCATTGTC TGGGATGTCCTTACATCTGGCTGAATTTGAAGGAGCACTTGGTGGAGTTCGGTTGGATAA AAAATTCATAAACTGACAAACAGTGCCTTTTTACACTAACACTCACTTTTCAAAAGATCC AATCTGGCCAGTCTCCATGCGCCAAGCAGATGTGCTGACTCTAATCCAGCTCATTGTCCT CACTCCACTCCGAGGAGTCTTGGAATGTGGGAAACTCGCGACCTTTACACACAGAGCATG CCCGCCTCACACACTGAGAATGTTGGTAATAGCAATGTCCTCAGAGGTCACCTGGCCAAC TCCTTTGCACAGATGAGGAAACTGAGTTCAAGTGGGGGAAAAGACTTGCCCGAGGCTACA CGGACATAAGCAACAGGGCCAGGGCCAGACCCCGGGCCTGCTTCTGCTCTGATAGGTCCC ACTGCTCAATTTCTTATACCACTTCCTCTAACAACGGACACAACACTGCCAGAGAGGGCT GCTCACCTGGACCATTTTGGTATGAAGGCCTTGGCCCATCTCAGTCCCCCCGTGGGTCAG CAGCACAGAGCCATCTGTGTACACATGAAGTAGGGCTCCTGCCTAGGGAAAGAGAAGGAT GCCAGACACAAAATTCAGTAAAATCCAACTCATTAAGGTTTGGGACCAAAGGTATGGAGC CCAGGAACAAGAGAACCAGCAGCATTTTGGATGTAAACCTCAGACAAAAATTATGGCAGT ATGAATCTCATGATTTAATTATATAGCACTTCAGTAGTTTGCAGAAGGTTTTCATATGTT TCTCTCTGTTTCTCTTGTTCTCAAAGGGAAATAGGTCAAATATCTGTCCTCACTCTGTAA GTGAAGAAACAGAACAAGAAAAATAGAGTAGCTCTCTCCAGTCCGATAGTTAAGGAAAGG TAAGAACTAGAGGTTGATCCCAGATCTCTGAGTCTCACTGCCCATGACCTACTGGACAAA TAGGACTGTGCAAGTTCGACTTTCATTTAAAGAGCAAAGAGTTCCTCCAGTAAGCCCTGT TACCAGTGACAACGAAATTTCCCTTGCAATACTGTAAACAACAGGGAAATGGGGTCCCAG TCCAGCGGAGATGGACACAATTCTATAAAGCAATTACCTGATTCAGAAAAGGAACTGTAA AGCTTATTCCAAACTTGGTGGGAATTATGCACAATCCTCTCTTTTTCCAACAATTCTCCC TAGAGAAAAAGGAATATTCTTATAGAACCTTCGCTATCATATTGAGGACATGAATATCTT TGGATGTTCACATCAAAACAGGACATCCTTGGGGTTGCCCACAAAGATGAGAACAGTCAG CTGGTGCACAGCCCACACCAGGGGGTCTTGTCAACACTCTTCTTCCCTGAGTGCAACCCG TACTGGGTCAGAGTGCCCTGGTAATCTTGGGCTGTCATCATCTCCAGGAGGCACTGTGCC TCACTGACAATAATAAAGCCTTCTCTGTGCTTTATATTTAATTATCTGAGTAACTCTGTG AGGAAGACAGAGCCAGCCCAATTATGCCCACTTTTCACATGATGAAACTGAGGCCCAGGG ACTCCCAAATTCATATTTATAGATCAGTGTCAGAGGCAGGTGCATAACTGTGACGTGTTA GTCCTAGGCCAGTGTTCTTTATCATACGGTGTGCCCAAAGGTTTACAAACGCGTAAAGAT GAACCACAACTGACAGGCTATGACACCGATTGCAGGCTGTGAGCCCACCTGCCCCGGGCT GAAGATCATTATAAGATCTTAAAGAGATGGCTGTGAATGAGTTGGCAAACTCAGCAGTCT CATAAGTTATCCATTGAATTATTAGCTTCCTATATGGGGTCAGCAGAAAGGCTGTAGGAT ATGAAACCCAGAAGAGCAACTGGACTTCTACTCCTAGTGCTTACTTGTTGAACTTGTCAA CCTCACTCTTCCGAGCATGATACTGAGAGCTTGCTAGGCATTCTTCCCAGCATCTGGGCA AGGTGAAACCCTCAAGCTTCTGGTTGAAGTGTGTCAGGTCCCCTTCTTTGTACAGGTTTT TTCTCCGCACCTTCCCAAGGAGAGAGACACAGAGGCCTTGTTGGCGGCAAGAGACTGTGG GGGCAGGGCACAACCTAAAGTTAAGCTTCCAACCCCCTCAGCAGCCCCTGCCTGTCATCT GCCCCCATGGGAGATGCCCAAGATACAAAGCCGCTGTCCCCCGAAGTAGTCTAAAGCACT CTGACTTGTGCTACCAAATTCTCAGCTTACCTCCTCTGCAGGCATCCCACAGGTCACTGC AACTTCACTCATCCAGCACTCGGCAATGAGCATCCCCTGGGGCCCCCCAAAGCCCCGGAA GGCCGTGTTGGAGGGAAGGTTGGTTTTGCACAGCCGCCCAGTGCCCCGGATGTTGGGGAT TTTATAGCAGTTGTCCATGTGGAATAAAGCTCGTTCCATAATCTGAAGCAGAGGAAACAA AAATGGGAGAGAACAGTGTACTGATTGCATTGGTTCCTCAAAGTAGGAACTTTGAGGGCT GTATCCATTGCCTGCCTTTCCCCTCTGCACCCAAGTTATTTCTCCCCCAGGATATTGCAG CAGCATCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCAG GCTGGAGTGCAGTGGAGCGATCTTGGCTCACTGCAAACTCCTACTCCCTGGTTCAAGCAA TTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGCACCACACGCCCAGCTA ATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCTGGAAGGTCTCGATCTC CTGACCTCGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCC AGCCTGCGGCAGCATCTTTACTGCACCTTATCCACCCACTAGTCCCCTCATTCAGCAACT CTGTGGAGAAATTCATTCCAGAGCCTCTAGTTGGAACTAATCACTTGCCTCTTTTTGAAA ACAGTTAACTTTTAAAAATTCATTGTAAATTAGTTAATGAAAACTATGAAACAGCCATGA AAGTTGTACTGCAAATAGTTTGAAGTGTCCCATACTTCTGTAAGTCATGGTATGAAAAAC AGTAGCCTCTTCCACTTTCCTTCCTTCTAGTCTCCAGAAGCAACTACTTACAATTCTCAT AGCTTATCATCTATCAGCTATTTAGATAAACTTATACGTCTCTAGATAATGTGGCTACAT TGCTATGTCTTGACTTTTTCAGTTTTAGACTTTTAGGTTGTCTTTCTTTTATGGAAAAGG AGAATTTAGTTTTGGCTTAGCCCCCTCCCTCCAGCCCTCACCCCTACCAGCTTCCTATTT CCCAGTATAGTTGTATTTTGATCAGATCAACAGTCAATTTAATATTATAACTCTGTAAAC ATTACTTACAGCTGAACCATGTAGTTACATTACAATTTCTTCTCTCTTGATAATATTTTT TTCACCCTGGAGTTAATAATTGTCTTTATTTTTTCATCTGCTTCATTTTGTATGTACTTA TTACTAAGCCAACTTAAAGTTTTCCCCAATTCTAAAAATCTGCTCCTAATATATTTTCTC TTTTCCCTCCTGAGCTCTGCTTCCAACATGTTCAAGCACATCAGATTTTCTATCCTAGAG CCATCTGGCCTACTCCAATTTAAATTCGCTGCCCACTAGATCTGCTATTCAGCTGTTACC TAAGGATTTAAATCTTAAATCCCCCAGTGGGATCCAAAGGGGTAAAGGGATTCATCCCAG GGATTCCCTTCACCTCTCTCCATATTGAATCCCCTGTTCCTAGATTCCATGCCTTTCCCT TTTTAAATTTTACTCCCTCATTTTGTTGGAGTACATCCTTTAATATCTTCATAAGAAAGG GTACACAAAGAGGAACATCTTTGACACCTTGCATGTCTGAAATGTCTTTATTCTACTTTC ACCTTTAATTAATGATTCAGCTGTATATAGAATCCTAATTTGGAAGTAGGCTTTCCAGTT TTTCTCAGCAATGTGAAGGCATTTTACTAGTACATTCTAGCTTCCTGCTATTGAGAAGTC CAATCAATGCCTTTCCAATTCTTGGAGAGTTCTGTTTTTTCTTCCTGAAAATTGTGAAAT CTTCTCTTTGTCCTCAGGTTTCTAAATTTCATAACATTATAACCTGGCATAGGTCTATTT TCTTTCATTGTGCTGGTTATTATATGGGCTGTTTTAATCCCAAAGTGTATGCCCATCAGT TTTGGAAAATTTTTTGAATTATTGATAGCTTCCCCTTCTCTGTTTTTTCCATTCTTTCTT TCTGAAATGTCTATGATTTGGACCTCTTGAACTGATCCTCAAAATTTTTTTGTATTTTCT CTATTTTTTCACATTGTTTTCCATTTTTGGGAGATTTGTCAAGTTTCTTTGAACCCCTCT GCTTTCATAGTGTCAAGTCATGAGAGCTCATTTTTATTCTTTGACTGCTCCATTTTAGTA ACATTCTGTTCCTTCTTTAAGTTGTAATATCTCATCTCTCTGGAAAGATCAATGGCAGCT TTCTTTTTTTGTTGTTTGTTTTATTTTGGTTTTGGTTTATTTCCCTATGGGTACTCTCTC TCTCCCACAAGTTGCTTTATGTGTCTTTGATAATTTCAGTCTTACTCATCCTAAATGATT TTTCTATGTCTCAATTAATTCTACTTTTGCTTTCCCTAGTACTTTATCAACTTGTATTTC TGTTTCTTTTATCATCTACTTCCCCTGCCATATTGTGAATTTCTTGAGGGCAGAAACAAT GTCATAGCCTTCCTTATGTAGCCACCCTAGGCACTTAATATATTTGCTGGATTGAATTGA AAATCTTGTAGGATGTCTAGGGACAAAGACTGTATGTTTTTCAACGTGATTTTTTCCCAT ACCAGAAAGCATGTCTTATACTTGAAGAGAACAAGAAATAAGAATAATTCTTTTTTTGAA CAATTTTAACCCTAGATCTGAAGTGTGAAGTTTCCTAACTGAGCCAATTAGGCAGCCCCT AGCAGAGAGGAGTGTGATCCAAAAGGGTAAAGGGGAATGTCGGCTTTTCCTGAAAACTTT AACCTTTTTTTTTTTTTTTCAAAGAGACAGGCTTTTGCCATGTTGGCCAGGCTGGTCTTG AACTCCTGACCTCAAGTGATCTGTCTATCTCGGCCTCCCAAAGTACTGGGATTATAAGCA TGAGCCACCGCACCCAGCCACCTCTTTTTTTTTTTTTTTCAAACAAGAATCTATACATAC GTAACTACTATGGTTACAAAATTAAGATTTAAAAAACTGTAAAAAGTGGTACCACCAAAA TAAATTTGTTAATTCTCACAATTGACTTTATTTCATCCAAGCCCTCTAGTTATTTTTCTA AACAACTCAATATTCCAAGTTCATCTCCCAAAGCTGTGACCACAATAATGAGGAGTACGT AGCTCCCACTTCTGGTCTTACCCTGGTCATTTACAATGTGACTGGAGGAGCATCAACTGA GACTAAATATAAAAGCACACGATAATTACTGACACATTACTCAGGATTCTATCTTGTGAG AAACTCAACATTGAAGTATATACAGAGACTTTCACTTCCATACTTCCATTAAGTACCACT AAAAACTCTGGAATTCTATATATTTATTTAAAATCAACCACAACAACAATGTAAGAATAC TCTGAAAAGTGGAGGAAAAAAAAAGGCAGTCCCAGTAGGGACTTTGCAACCCAAGGAATG ACATGATGGTGAGTTCCAGGGGTTTCCTTTTTGCCTCATCTATATATCCCAGACTTGGGG CAGGAGCTGGCAATCCAGAAATGCCAATGATGACAGAGACCAAAAAGCTCACTATATATT CCAAATCCTTTTATCTCTAGCCAAAAGACCAAGAAAAGGGCAGTCTAGCAAAACTAAACA CTTTTAGACAATAAGTACCCCAGCCAAACATCACAGAAAAAGAAAACGTAGTCTCATTCC TACTCACACCTGCAAAAGCTCAGTAGGAGCCCAGACTTCCACATTCATGAGGCTGTTATG AGATACCCCAACATTCCTGCTGGGATGGTGCCAGAGGAGACCAGATCGGGAGTCAAGACT TTCATTGCTGATGGCCAGTCATAAGGCTGTACCTACACCTTATGATGGAGTCACTGGAGA ACACATTGACTTCCCCACCCACATAACAAAGACACACCACTCTTCCCTTCCTTTCTGGTT GTGTCAGAAAAAGTCTAGTGAAGAGTCAAGGCTTTTAGCACAAGCCAGTGGTAAAGAGGC CACCCACACCATGATGTCCATGGACAACACGTGGAATGTAGATCTCCCATCTCTGCCCAG AAGTAAGAAGGAGTTGTTCCTAACCTGGGTATCAACAAAGGCCAAGTGGAAGATCAAGAT TTCTACCTCTACCTAGCAGTGATGAGGTGGCATCCACCACTGCTAGAGCAAGGTCAGAAG GAGCCAATTAAAATAGAAGGCTTAAATAGATCCAAGCTCTCAGAACATCGTCATCACCAC CATCATCTGTACATTAATGACGGGTTTCTCCAAGTTTCAGTGAAAAATCACTTGTCATAC CAAGTGATAGGAAGATCTCAAACTTCCTGAATAATAAAAGATAACCAAGAGATGCCATCA CTGAGGTGACAAAGATGTTAAAATTATCTGACTGTAGTTTTAATGCAGCCATGAAAAAAA TGCCTCTGAGATCAATTGTGAACACACTTGACAGAAATAAAAAGCTTCTGGAAATAAACA GATAGTCTCACCAAAGACATAGAAGATACAAAGAAGAACCTAATGGGCCTTTCAGAATTG AAAAGGCAACAACCAAAATAAATAGCTTATTGGGTGGATTCAACAGCAGAAGAGAAGGGA CATAGAAGAGAATCAGTGAACTGAAGAATAGAATAAGATATATTATCCAGTCTGAACTAT ATTGAGAATATGGAATGAAAAAAAAATTACAGTTTCAAGGACATTTGGGACTATAACAAA AGACCTAACACTCATGCCATTGGAGATCTGGAAGAAAAGGAGAAAAAGAGAAGAGCATGA AAGTACTCAAAGCAATAATAACTGAAAAGTTCCCAAGGTTTCAAGATATGTAAACCTACA GATTCAAGATGCTTGGTGATCTTAAAACAGGATAAGCCTGAAGAAATCTATGGTAAGTCC TATCATAATTAAACTTCTGAAAACTAAAGACAAAGGAAAAATCTTGAAAGCACCCAGAGA ATATGACAACTTACCTATAGGGGGAGCCTAATTAGAATGACAGAGGATTTCTCATCAGAA GCCATAGAGACCAGAACGAAGTGGCAGTTTTTCAGGTGCTGAAAGAAACGAACTGTTAAC TCAAAACTTAATGCCCAGTAAAGTGATCCTTCAGGAACAAGGAAAAAAATCAAGACATTC TCAGATGGAAAACTAAGAAAATGTGTCCCCAGCAGACCCACAATAAAATAATGACTAAAG GAAGTTCTAAACAGAAAGAAAATGATAAAAGAAGGAAGCTTGGAAAATTAGAAGGAAGGA AAAACACTATAAGCAAAATCATGGGTACAAGCAGTAAGCTTTTCTTCTCAGTTTTTAAAA TTGTCTGATAGTTGAAACAAAAATTAAAACACTGTCTTGATGTGGTTCTAAATGAATGTA AAGAAAATATTTAAAATAAAAATAATATAAATGGGAAAGGGCAGAGTCATAAAGGGAGGT AAGTTTTCTATACTTCACCAAAACTAGTAAAATGAGAACTTCAGTAGGCTGTGATAAGTT GTGTATATATAACATAATACCTTGAACAATGACTAAGAAAGCTATGTAAGAGATACTTTT AATAAAAATGGAATATTAAAAAAAATGTCCAAGTAACCCACCCACAGCAAGGCACACAAA AGAATACAGAGAAATGAAAAGCTGATAGAACAAACAGAAAACAAAAAATAAAGTGGCAGT CTTATGCCTCAACACATCAATCATTATATGATGTATAAATTGTATAAATACAGTTAAAAG AGATTAGCAGAATGGATTTACAAACATGACCCAATTACATACTGTCTTCAAGAAAATCAC TTCAAATATAATAATGTAGGCAAGTTGAAAGTAAAAGGATGGAAAAAGATATAACATGCA AACATTAATCAAAAGAAAGCAAGAGTGGCTTTATTAATATGAGATAAAGTAGACTTCAGA GCAAATACAATTACCAGAGACAGAGAGAAGGAGATTACATAATGATAAAAGTGTCAATCC TCCCAAAAGACAGCAATACTAATTGTGTCTGCCCCAAATAAAAGAGCTGAAAAAGATATG AAGTAAAGACTGGTAGAACTAAAAGGAGAAATAGAAAACTCCACAATTACAGTTGGAGAT TTCAATGCTCCTCTCTCAAAATTGGTAGCAAAAAATAGACAGAAAATCAGGAAGGGTATA GAAGAACTCAACACCACCATCAGGATCTAGTGGATATTTATAGCACATTATACATGTGGT AGGAAAAAGAAATGCCTCCCCAAAGATATATTCACTTTCTAATCATGGAACCTGTAAATA CTACCTTATATGGCAAAATATGTGATAAAGTTAAGGATCTGGAGAGAAGTAGCTTATCCT GAACCATTGGAGTGGATCCTAAATGCAATCACATGTCTCTGTAAGAGAGAAGTATGTCTA GGTAGACAAGAATGGACACACAGGAGAAGGTGATGGGAAGACAAAGACAGAGATTGGACT GATGCAACCACAAGTCAAGGAGTGCCACCAGCCACCAGAAACTACAAAAGGTCAGGAATG GATCCTTCCCTAGAGCTTCCAGAGGATGTGCGGTCCTGCCAACACCTTGATTTCAGACTT CTGGCCTCAGAACTGTGAGAAAATAAATGTTCGTTATTTTAAGCCACCCAATTTGTGGTG ATTTGTTATAACAGCCACAGAAAACTAATACACAGCCATCAACAGCAAAATACACATTCT GCTTAGGTGCCCGTGGAACTTGTATCAAAACAGACCATGTCCTGGGCCATGATATGAACC TCAACATACTTCAAAGAATTGAAATCCTATAGACTGTGTTCTTCAACTAAAACGGAATGA AACTAGAAATCAATAGAAAGCCTCAGGATACAAAGATAACTGGAATATCTATAAACACCT GAAAACCAAACAGCATGCTTCTAAATAATTAGGGATCAAAGAGAAGGTGTCAGGGAAATA AACAAGCAGACCAAAAATACAAGAAAAAAATGAAATACAACATACCAAAACTTATGGGAC CTGTCTAAAGTAGTGCTGAGGGGAAACTTTACAGCACTAAATTGAATACATTAAAAAAGA GGAAAACATTCTCAGATAGTTAATTTAAGCTTTCAACTCAAGAACCTAGAAAAAGAGAAG CAAAATAAATCCAAAGCAAACAGAGTGAACGAAATAATAAGGATAAGAGCAGAAATCAGT GAAATTGAAAACAAACACAATAGAGAAAATCAATGAAACAAAAACCCGGGTCTTTAAAAA GAGCAATAAAATTGACAAACCTCTGGCAAGACAGAAAAACAAAGTGAAGCCACAAATTAC CAAATCAGGATTGAAACACGGGCTATCACTACAGACCCTGAAGACATCAAAAGAGAAATA AGAACACACTATGAACGATTCTACACACATGAATTTTTTAATAACTTAGACAAAATTAAA TTGAATTCATGGAGATAAAGAGTAGAATGATGTTTACCAGAGGCTGGGGAGGGTAGGGGG ACAGAGGATAAAATGGGGATGGTTAATACATATAAAAATATAGTTAGAATGAGTAACATC TAGCATACAGTAGAACAATATGGTGACTATAATATTTTTAAATATATGATAATTTATCGT ATATTTAAAAATAAATAAGAGTAGAATTGAAATGTTCCCTAACACAGAAAAATGATAAAT TCTTGAGGTGATAGATATTGACGTTACCCTGATTTGTTTATCCTGATACACTGTATGCCT GTATCAAAACATCATATGTATCCTATAAATATATACAACTACTATGTACCAATAATAATG AAAAACAAAACATTTTTAAATGAATGTCTCAAAATACAAAACTACCACTTCAGTATGAGA TAGATAATTTGAATAGTCCTAGAACTATTAAGGAAATTTAATCAATAGTGTTTTTTTGTT TGTTTCTTTTTTTTTCAAGTATTATACTTTTAAGCTCTAGGACAGATCAACGAGACAGAA AGTTAACAAGGATATCCAGGAATTGAACTCAGCTCTGCATCAAGCTGACGTAATAGACAT CTACAGAACTCTTCACCCCAAATCAACGGAATGTACATTCTTCTCAGCACCACATCACAC TTATTCCAAAATTGACCACATAGTTGGAAGTAAAGCACTCCTCAGCAAATGTAAAAGAAC AGAAATTATAACAAACTGTCTATCAGACCACAGTGCAATTTAATCAATAGTTTTAAGGCT ATCAGAAAAGAAGTCTCCAGGTCCAAACGATTTCACTGGAAAATTCTACCAAACATTTAA AGAAGAATTAACACCAATTCTACACAATCTGTTCTAGAATTAGAAGAGGAATTCTAACTC ATTTTATGAAGCTAGTGTTATCCTGACACCAAACCCTGACCAAGATGGTATAATTTTAAA AGAAAAAACTACAGAGCAATATTTCTCATGAATATGGATCCAAAAATCCTTAACAAATTT TAGCAAATAAAATTTGGCAATATATTAATTATACCATGACCAAGCTGGATTCATTCCAAG GACAGTGGTTGGTTCAGTGTTTAAAAAAATCAATGAATACAATCCACAATATTAACAAGC TAAAGAAGAAAAAATCACATGATCATATCAGTCAGTGCAGAAAAAGCATTTGACAAAATT CAACACCCATTCATTATAAAGATGCTCAGAAAACACTAATGGAAGAAAACTTTCTTAATC TGATCATGAGTATCTACAAAAAACAAACAAACAAACAAAACCCTACCAATAACATATTTA ATGGTGAAAGACTGGATGTCTTCCCCTTAAGAATAAAAACAAAGGAAGGATATATGACCT ATAGTTCTGCAAGGTCTGGCTAGCCATCTCAGTATGTAAAGAAAAGGAGATGAAAACATG CAGATTGGAAAGGAAGAAAAAAACCATCCCTATTTGCAGATGATAATGATTGTCTGCAGA GAAAATCCCAAGGAATCTACAGAAGAAATCCTAGAACTCATAAATGAGTTCTGCAAGGTC ACAGGATATAAGAAACACAAACTGAAATCACAATGAGCTATCACTTCACACCCACTAATT CTAGTGGGTAAAGACAGACAATACCAAGTGTTACTGAGGATGTGGAATCCCTAAAGATTG TTGATTGGAATATAAAATGGTGTAGTCACTCAGGAATATAATTTGATCATTTCTTTTTTA AAAAAAATCAATAGAAATTAGGTAGATCCATTTATTTTTTAAATACAAGAATAGTTTTGG AAGGGCTGTTTGACAAATTCAGCATTAACTGCCAACTCTATAGACATGTTTAACAAAACA AAACAAAAACCAAAAAAAAAAAAACAAGGCATTTACTCTTGGCCCTTTTAGTACAGGCGA AGTGTCCTATTGCATCACAAGCGCCAGTGATGCAGTAACAGGTCCAAGGGCATAATATCA AAGATGTTTTTTTCCAACTGTGATTTAGTTAAAAAATAACATAATACAAACATATATTAA TGGCTATCAAGACCACCAGTGATCTGCAGAATACCTAGAGGCCTACCTACTTAGAAGGCT GAAACTAGTAAAGCAGTATTAAAATCAGTGTTTTTATTCTTAGATTCACAATGACAGAGT GAGATTTCTTTGATTCCAATTTTATAAGGTGTGGTGGGGAATTGAGAGGAGATATTGGGG AAGACTGGCAGTGTGCCCTGAGTTAGAGTTGGGAATGTGGCTCAAATTAATCAATATTCG GATTAGGATATTGTTTTAGAAAATTTTAAATGTGTCCTAAATTGTGGCATATTGAAAAGG ATATTAAGGAACAATGATTCATTAGCCCTAAACACAATTTAATGAGTGCCATCAATGGGC TTAAGAAATAAGCAGGGATGGGGGATGGTGAGGCAAAATGAGGTGAAAGAGAAAATGGTA AGTGGAAAATATGCTTGAGCATTGGAGAATGTGAAAAGGCCACCAGAGAAACTCCTTTAG TTATCACTCAGATGTGCTCTTCCCATTGGCTACCTGCTCCTGATCACCCAAACACCAGTT TTAGAGCACAGGAGCAGTAACCCCCTTTATCTGCAATTTCACTTTCCGTAGTTTGTTAAC CAAGGAAGCCTTGGTCCAAACATATTATGTGGAAAATTCCAGAAATAAACAATTTATGTT TTAAATCACAAGTCGGCCGGGCAAGGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGG ATGAGGCGGGTGGATCACCCGAGGTCAGAAGTTCGAGACCAGCCTGGCCAACCTGGTGAA ACCCCGTCTCTACTAAAAATGCAAAAATTAGCTGGGCGTGGTGGGGCAGGGCACTTGTAA TCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCGGAGGTTGC AGTGAGCCAAGACTGCACCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCA AAACAAAAAATAAATAAAATAAATCACAAGCTGTCCTGAGTGATGAAATCTGATGATCTC CTGCTCTGTCCTGTGCGGGATGTGAATCTTCCCTTTGTCCTGCTTATCCACACTGTGTAC TACCTGCCCCTTAGCCGCTTAGTCCCGCCTTGGTTGTCAGATTGAAAAAACATAGTCTAT AAAGGGTTCAGTACTATCTGAGGTTTCAGGCACCCACTAGGGTTCTTGGAATGTATCTCC TCCTGCAGATAAGGGAAGATGACTGTATAACAAGGGGTTCAGTACTATCTGAGGTTTCAG GTGTCCACTAGGGTTCTTGGAATGTATCTCCTGCAGATAAGGGGAGATGACTGTATAACA AGGAGTTCAGTACTATCTGATGTTTCAGGCATCCACTGGGAGTCTTGGAATGTATCTCTT GCAGATAAGGGGAGACTACTGTGTTACATTTCAGCTTCCATAAAACTTTACTAATTTGGA TTAAGAACACAAGCCTGATTTAGTAAAAAGTATCCATAAATATTCAGAGGTATAGTTTTG TTTCATCAAGTAAAAAGAGCAACTAATTCCAACTGTTGAAGTAGTAACAAGTAAAGACTT CACCAGGCTTGCCTTGATGAAGAATTAAGACATATTTTTAGGTCAACAGCACAAGATTGC TGAATAACTTGTATGCTACAAACACGCTCCTTCCACTCATCGTAACAGCCCAGCAATCTT TACTATTCCAACTTGCTGAGAACCATGTCAGATGTTGCCTTCAAGAATGAAATGTTTCTC AAAACTGTTCTATCAAATTTAGTAGCTATTGGACATAAAACAGGTAATTATTTCAGACTT TAGCCAGTTTTCATGAAGTATTTATCTCCAGCTTCAGTTTATTCCAACATTAATTTATGA AAGGACAGTTATTAAAATCAGCCATTTCTCAGACTGTAACTTTGAAATCATAAGAAATGG ACAATTAAGCTCACTAGTCAAAATCTTGATTCAAGTGATGATCCAATAGCTTATAAATGT CTTCAATAAACTGAGCTTTGAAGCAGAACAAAAAACAGAAAAATCTAAAACCTCTCTATC CCAAGCACCAATAATGGAGGCTAAGCAATTATACCTACAAATCCTTAATGACAGGTCTCT CCTAATGAAAAATCCTGAGATTTAAGCACTATGACTTACAGAAGGCAGGTTGGCTTAATG AGGAAATTTACTTTCAATAAAAAGACAATCAGCAATATTTTATTTTGGACACTTAGCATT TCACAGATCCTCAATATGTTTTGAGGTAGGTCAAATATTAATAGTGTATTTTACAAACAA AACTCAAGCAGATGCTTTGTTACTTGTCCCAGACCACAGAAGCAGTTCTATCATGGTCAG GAATAATACGGTCTCTCTGATCTTTCAGATTAATCTTTCATGTGTGAATTTAATGGTAAT TGCTTGCAAATATTCATGAAAGAAACAAAAGGCTAGATATAGAAATTCTACTTTGGGATA TTTTAAACTCCTTAAATTTATCCTATAATGAGTATATACTTGCTCTCATTACAAATATAT ATATATATATAACTGATCTTTACAATTACAAATGAGCACAGGACTGACTATGTTGCTTTT CTGCCTTTTGGGGTGAGTAGAGCAGGAAGATAATCAGCAAGCTTTCCTCAGAGCACTAGG CAGCCTTTAACTGAAGGTGCTATGTTCGAGGCACCATTGACTATGATTTGGGATCACAGG GGAGCAGATGTACTAGTGGAACCAGGATTCAGAAAAGATGTCTGGATCCAAAAAGGGGAG GCTCTCTGCAAGTCATAGATGAAGAGAAAAACCATAACATCTCAAGCTACTGATCCTGAG TGTCACTCTATGGCATTACAACTACTTGTGAGAGGAGCTCCTACAAGAGCAGTAAGCTTG TCCCAGTAAAGCCTATTAAAGTTCTTACTAACTAGATAAGCCACAAGTAAAACTAAATTG GTATTTTATTAAAGTGACATCTATAGAAGCAAATATCTAAACATTTTTAATATGAGTTTT ACCTGTCATGTAAATTCCTCATTGTCACAAGCCTAATTCAATTAGCTCGTCATAATTCCT AAAGTAATTTACTAAAATTCAGCTCATCTTGACATAGGTTCTTGAGCCAGTATTCCAAAC TGTTTCATTATAAAGTTCCTTTTATTTAAACAATTGTAGAATATTAGTAATAATAAAGCC CAGCTCTCCCAGTGCCTGCCGGGCCGCCTCCGCCCATGAAAATGCGATCATTTCTTAAAA TGTTAAGCTCACCACAGATTCAGCAATTCTATTCCTAGGAATTTAGTCAAGAGAAATCAA AATACATGTCTACATAAGGCTAGTATGAGAGTGTTCAGAGCAGTATTATGCATAAAAGCA AAAAACTGGAAACAACACAAATGTCCATCAAGTGGTGAATGGGAAACAACATATGGTATA TCCCTATGATGGAATATTATTCATCAATGAACAGGAGTGACGTAGTGATACATGCTATAA TATAGATGGGCCGGATGCAGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGG AGGGCTGATTACTTGAAGTCAGGAGTTCGAGACCAGCCTCATCAACATGGTGAAACCCTG TCTCTACTAAAAATACAAAAATTAGCCAGGCATAGGGGTGCATGCCTGTAATCCCAGCTA CTCGGGAGGCTGAGACAGGAGAATCGCTTGAAGCTGGAGGCAGAGGTTGCAGTGAGCCAA GATCGTGCCACTGCACTCCAGCCTGGCGACAGAGTGAGACTCTATCTCAAAAGAAAGAAT AATAATAAAAACATAGATGAACCTACAAAACATTATTCTGAGAGAAAGACACCAAACAGA AAAAACTACATAGTGTATGGTTCTATAAAATGACTTGACTACAAGACGGAAAGTAGATTA ATGATGACCTGGGCCTATGGAATGGTAATGGGAATGACTACAAATGATGCAAGACATCAT TCTGGGGTGATGGGAGTTCAAACACTGGATTGTGACAGTGGTCTAACAACTCTTGAAATT TACTAACAACCATTAAATTATATACTTCAAATGGATTAACTTTATGGTATGTAAATTATA CTTCAATGAAACCATTTTTTAAAAAGCAATTCGAATTATTTAAAATTAAAACATCACAGA AATGTGTAACACAGAAAATGACAGTGTGTACGCCTCTCAATACCATTCCAATCGTTGTTA ACAATTTGATCATCACTGCTAACAGTTTGGTATATGTTCCTTCAGACACTTTTCCACGCA TGCTATATATAGTAATATATATTAGTATTAGTTTATATGTTACTGTATATATATATTACT ATTCCATGCATATGTACACACACACAATGCCACCACACTATACATAAAACATTGTAACTA ACTTGCTAGCTTGGCAAATTATCTTGAACAGGAAGGATGGGTTTTTAACCAGAGAAATAA TACGATCATCATTGTGCTATAGAGATTAATCGAGGATGGGAAACCTGAAGGTGGGGACCC ATTAGGAGACTACTGCAACAGTAGCAAGCAGGGACTGGGGAGGCCTGTGCCTGCGTGGGA ACAGGCTGACCTCGAAGTCAGCTCTGGGTGCAGGGGCGGCTGCAGGTCCTACTCACACTC TGAGAGAGATCCTGGGTGTTCCCCACATTGCTGAAGTGGTCCACCTCAAGAGCCACAACT GTCCCAGTCTTCATGAAGCCAACCTGATAAAAGGAGAAAGGAGAGGGATTTATCATAAGT CCCGTTTCCCCCACCTCTCTGTCTCCCTCTGATCCTCCCTCCCACTTATGTCACCTGGAG GAAATAAACAGAACACCACATCATCCCGTGAAAAAAAGGTGACCTTCAGAAGTCACCAGA AGGTAACAAGTGAAGAAGAGAGGAACTGACCTCTCCCCAGTGGCACACACTTGGCTCCCC ACCCCTGGAAGCCCTTGTCCCCACACCTCTTCCTCCTGCTACCGGCACCTGGCTTCTGGT CTCGGAGGGGAGTAAGGAGGTTGGAAAGAGAAGGCTGGTCACGATAGGGCGGGGGGGAAG CGCAGGGAAGAGAAACTAGGAAAGATACCGGACTGTCTCCTCACAGATTTTGGTCAGAAG ACACAAAAAGTTTCATTTCACAGGAGCACGCAAATCCTTGACCTTATGTACACTGTTAAA ATACCCTTTACAGGCTGTTTTACACACACGGAAACTGGGACCCCAGAAGATCAAGGAATC CTCTTCAGGCCCACAAGAATTTGGGGCTAAGAGAAATATAATCCCTTGCTGGGAGTTAAA TCATGAAACAAACTCAGAATAGGTCAAAGGCCATGTTCAAGGCCAATTCATGGAGAGAGG GCTCTCAGGTTTCTAGAGCTAGGCGGAGCCCCATAAGGCTTTGCTGATGTGTACAGGGAA AGGGTGCATTGGTCATCCACAGAAACCCAGAAGAGGGACTGTCCCAGAGAGAAGTGTGGA CCGTGTCCAACCATGGTCTGGAAAAGTACATACCCATCCTAACATCTTGGGCCTGTCCAG GCCCCTGGGAAGTTTTATTTCTCACAGTAAATTACTAAGCTGTCATTCCAATTTTTACAT CAGGCCTGTGATCATGTTAATGTTGGGCTACCAAGCGCGATGGTTTACCCTGAGTATGCT GGTGAATCATGTTTCTGAGCCTGACCAGACTCAGAACACAGCAAATCCACAGAAGTCACG AATGCCACCCTTGGGAGATGGGGTGCCAGCCTCCCTCAGCACTACCTTTCTGTGTTGCTG TTAGCCTATTTGAATTTCTCTTCTTGCTATATCTTATTTGAACTTCTACAGATAGGCAAA AAGTAGGAGTGCAGCTCAGGATGCCTGGACATTCGGTCCCAGCTTTCCTCACAAAATGGC TCATCCCGCCCCAGCACAGCCCCAACATCTAGAACCTTGTATCTGGCCAGGAAGGGATGT CTGCCACCAGTTATCAGCATGTCCTCATCACGGTCCAGCATGCATCGCACAGGGCGGCCG GTCCTGGGGGTTACCGACAGTGTTAGAAGCCTGTGAGCCTTCAACAGCAGCTCAGCCCTG CAAGTCTCAGAATAAAAACAGCCGGGAAGCCATCTTTTCCACCTGCACGCTGAGCAGACC TGTACAGGGCTGCTTTGCCATCTAGGCACTGTGATAGACAAGGTGGAGAATATAAGGAAG CGAGGTATGTGCTTTCATTTAGAGAGCTCACAGCCAGTAGGAGAGATCAGAGGTGGATAC CTGTGCCAGACCACAACGGAACAGGCGATGTTACCCTCCCACTATGCCCAAGGGTTCTAA AAACAGAGGGCTGTGAGAATTCAAAGCAGGGGGAAACTAATTCTAACAGGGGGAAGTCCT GAAAACCTTCCTGGCACAGACAGCCTTATTCTTCTTCCCAGAGCCAGATGGGAGAAACAG GCTTTGGAACTCACTTATATGCAGCCAGGGCCACTGCCGTGGACACCACAGTGCTCCGGG TCTCCTTGCCTCCAAAGCCTCCTCCCATTCTCTTCACTCGAACCACAATCCGGTTTGCTG GAACCCCCAACATTTTTGCAACAAAGCTCTGTGAGTGAAAGACAGAACATTCGCACTGAA TGCATTACCTGAACTTATTTCAGGCCTAAGGCAGAGCCTGTCCAACATGCATGGACCTAA TTACTGCTGCGAATTCTGAAATTCCTTGATTGAAAATCCCATGCAGCTTTGTGGTTAGTG ATGCTGGGGCCTGCCAGACTGAATTCAGCATTGGTTTTTAACCAGAGGGCAAGCAGTTGG TCACAGAATACTTTTAGAAACTTATTCTGTCTGACCAGGTGACCAGCGACTGGTAGATCA TGAGAGTAGGACCAGCTGCCGAAAACACTGGCAACCGCTGTCACATTACAGGCAGTAGAG AAACAAAGAATATTTGAGCTGCTGTAGATAATTTAGTGGTCCCTGTGGCTATGACTTAAT CCAACACCTTCATTTTACATATGAGGAAACTGAGGCAGGATATGACTTGACCGAGGCCAT AGGCACTGAAATGATAACTGCCAACATGTACCAAACTCTAGTCTAAATATTAAAACTCAT CTAATAATTATGACAACCCACCCAGGCCCCATTTTATAAATGAGAAAACTGAGGCTGAGA AAGGTTATGGAACAAGGTCAGTGATACCAGCTTGTTGGTGAAAGAGTCTGGCTCCAGGAC TATGACACTCGAGTACCCTCTGGACCAGCCCACATCTCCCTCTTCCTATTTCCCACATGG CCCTCCTGGTCTGCTAGGAGCTCCCCGCTACCCTGACAGCCCCTTGAGCTGACCCAAAAG GCATCTACCTGGGTCTTCATGGTGTTCTGTGTAGACACAAAGAGCTCCATCTCCCCTGCC TCGCCTTTTGGAACAGCAATGGTGCAGTGAGTCTCCAGGTAGAAGTGCTCTTGGCCACCG ATGTATATCTCCCCTGGGGAAGCAGTGAGATCCCTCACAGTGAGCCCAATGCTGCAGAAG GGGCCAGCTTGCCTAAGGAGAGAGTATACTCTGCCAAGTGGTCTGGGCAGGAAGCAATGG CTACCTGAGGGGTAACCTCAAGGTTTCCCACTTGGGGTGGAAAAGGATCCCAAAGTCTTA GCTATCTGGGAGCTGAGTGCTCCAGCCTCATCCCCACCCCCACAACAAAGAAAGAACGAC ACTGAAATGCATCCAGTCCAAAGTTCTCTTCTCACTGCAGCTTATGGAAATCAAGGATTT CAAAAACCATCATTGTAAAATTTTGGAAAAAGTAAAGCAGGGATTAATAGATGTGATTGA AACACTGAAAACCAGCGCATGTTCCCGAACCTAAGCTACCAGGCCTGGTGGAGAGTCGGC TTCATACCAGGCTTGTTGGAGAGTTGGCTTCATAGTGACTTTGCAAAGCACAACAGCCAA TGTAAAAAACAGTTCCAAAAGAGGTAGTCAGCTGTGTTGTCCTGGGGTGGGAGCAATGGA TTTGATTTCACAGTGTCAGAGACAGAGGTGGAGGGAGAGCAGGGCAAAGGGAAGAGGAGG GAGGATGCTAGTTGAAGATGGGTAAGGACTGCCTTCAGGTAGGGGGAGGATGAGAATTTA TGCGGTTAGAGGCCTGGCAGACCTAAGGCTGTCAGGCATATGTGGCTGTTATCATCCCTA GTTGGTCTTCCGGATCAGAATACTCTAGAATCTCTCTAGAATCATTAGGTCCAGCCTAGA GACAGGAGAGTAGAGATTAAGATAACTGAAGCTCTTTCCCATCCAACTGTCTCCTATTTT GCTACAAACGTAAGAGGGAATCTTCTGTCAGGAAATGTCCAGAAATCACTTCCCTGCTTC AGGGTTCAATGCATATCTCTTGAATTTAATTTGCAAACCAGGGCCACCCCATTCCCACTG CGGCATGGAACAGCTCTACCTGACACAACATTATCTGCTTCGGAAAACCCCTTCTTTAGG TCCCCTTTCTCGATCTTCAGCTCAGGTCCATAAAAGGAGTTGTTCTTTATAGCATCCTGA GGATCACAAAGAAGTTTCAGAAATGTGGCTTTTAGCAGGGAGGGAAAGATAGGTTCTGAT TAGGGAAAGAGAAGCTCTCTGAATTGTTGACTCTCTCTTTCCATAAATGAATCTCTATAT GCTTCACATACAGACTTGAAGTAAGCTCTACTATAGCCCAGAGAATCATATTCCTCCATT TCCTCAGCTGTAGGTGGACAACCCTGGACCTTGAGGAAAAGCAAAGAATACCACAAGGAC CAGATGGAGGTAAAATTTTGAGAAGGAGGAACTCAGTTTGGCTGTTGTTAGTGGACTGGG CATAAGATCATAAAGGGGAAGGTTTCATGGGACCCCAAATCCCAGGGTTGAAAGGGATTT AAAAACCCATCTAGTCAAATCCCTACCTGCTGCTCAAATCCCCTCCAGGGGATCCTAATA CATGCACATCCAGGGACGGGGAGCTCACTCCTCTACACAGGCAGCCCATTCTCAGTTACC TCAATTGTGATAATGGCTGGTAGTTCTTCATAGGTGATTTTCACCCCTTGGGCAGCTCTC TGTGTGTGTTCCGGGGTGTCAGCAACCACAGCACCAATGATATGCCCAACACAAGTAACC TAGTAGCAGAGACAGACTGTTAAAGAACGCAACCAGGCTCATGGTGAAACAAATTATTTT TGGATTGTTCAAAAAGCCAAAAGAAGTCCCTGCCCTCACAATCAAAGCACACTTTAGGAA TGCCCTAGGGCCTCTTAATTTCCTTATCCTACTGATTGAGGATCACTAGGATCAAGATGG CAAACACATTTCATCTCAAGGGCCAATTCTGAGTATTTAGTACTGGCAGACTATTGAGAA GCTGAACCAGATAGAATGTGGCAATTGATTCCTTGTTTGCCATGAGCAGAAAGGGGGATA TGGCACCAGGAAGTGCATTTGTCAATTCGGATTCACTCCAACACCATTGGTCTTCCTATG GAGACTCAGAAGGCAAGGCCACATTTGGCTAGTTACTATTGACAGATCATGACTAACCTT AGGCCCTGACCCCCAGTTTTATTTTCTTTTCACCTCACCACTCTCTTTTATGTTCTATTT CCCAGATTTATACCAAAAGCTTCTCAAAGGCTGTAAAGGCTGTAAGCATCAATATAAGGC CTGTAAGACACGTACTTACAAGACATGATACTTTAAGTATCATGTCTTATACTTCAACTA ATACCCAAAAGCAGTAGCTCTCAAATACTGGTTCTTAGACTTGATGACCCATAAAAATAT TTTTAAAAATTTATATGATAATGATTGTTGTTTTATTTTGTTTAATAATTCAGTTTCATA AAAGCTTAATGGATCTCCTTCAGAGATAATTGTCATCCAACATCCCCGAAAAAGTAAACA ACAAAAAATTTTTGTACAACACATCACTTTAGAAGATGAAGTTTCTGACAATAGGAACCA ACAATTAGTATGCATGTCTCTGATAATTATCTCTTATGGCCCAAATAAGCTATTGACTCA GTTGGTTAGTGCAATGGTGGTTAAATCTGGCTGTTGGTTATTGCAATGGTGGTTAAATCT GGCTGACTTTCACTAGCCATAATGCTAGCACTGCTCTGAGAAGCTCTTAAAGTATGTAAA GCAATTTGTTCTTCTATGAAATGCTCTCCTCATGGAGTCTTTGTTCTCATATTTTTAGTT TTTTGTTATCTCCTTCACTTTTACATCAATAATAAGATGAATTCACTCTTCAGAAGTACC CACTCATGTCTAATTTGCAACATTGGATGTCTATTGGAATTACAAAATGACTGTCGAGAA CTATCCTATGAGTAAAATATAAGGACTTTTGTAGCAGCTGTCTTAAACATTTGAAAAATT TTGTTTGTTGTTGAAGAATTCCACATAGTTGAAATCAATAGATAAACTTTCATGTAAGTG AATTACCAATTCACGTAGTGGTGGTATTGTGATTTCTAGTTAGTGTACTAAATGTATTCT TATTTTATTTTAATTAAAGAGCTTACTGTTGTCCCTTAAGAACCGAATTGTTAGTTCAAA TGCAATCACCAGTGTTGTTTTACTGCCACTTTGGCATAGAGACATCCTGCCATGTACAAA CAGCAGCCATCAATTAAATAAACAAGTAACATATTCTATCTTTTTGGATTGTCCTGAATA TGGGCCAACTGGATGATGGCCATAATCCATGCAAATGTATAACCTTTCCAGATCAGGAGT TTGGAGCAATGTACACAAATTAAAACTTCAATACTTATTCAATTTACTTCATATAAAAAA ATCCAAGACTTACCTTATCCTTCGCAAAGACTGTCTCATCATTACAAATTCCAGTTATGT TACTCCCAGGAACATCATCAGCGGAAATGAAACAAACAAACCCTGGAACCTTCTTAGCTT CTGATGTATCTATGGACCTGCAAGAATGAGTGGTGTGAGGGGCCAGGTCAGCAAGCTGGA GCAGGGGACCCATCACCTGGTTGGACAACCCTGTTCTTATTTTGATTGGCTTGGCTCCAT CCTAATTCCTCGATTCTCTGCTTCTTTTCTATTAGATTCTAATTCAATTATATCCTATTC TGCAAATGTTGATTAAATCCTCACCATGTTCAGGCCACTATGCTGAATGTTGCTGGGGAT ATAAAGTGAATAAGCCAGCCAGGCACAGTGGCTCATGCCTATAATCCCAGCACCTTGGCA GGTCAAGGTGGGAGGATCACTTGAGCCCAGGAGTTTAAGACCAGCCTGGGCAACATAGCA AGATCCTGTCTCCATTTAAAAATAAATAAAGTGAAGAAGGCAGGCCAGGCCTCTTTGGAT GTTACGTGATGCTCTGTCTGGTCTCCAAGTACAAGCAAGCCATATCAGAACGAACAGCAC TTACTCTGGAGCGCTCTGGCTCATGCACACATCACACCTAACTCCCTCCCAAAATCAGCA CATGGAGCCCGGCTGTGCCACTGATCCAATGGCCCTGAACAGCTTCATAAAGCTGGATTT GTCTCCCCACATTCATTGTGCTATCCCAGCATGACAGGGCATCCTACCATAATTAGGCAA CACGAACCGCAAAGGGAGAATGCCCGACTATATGATCAAGGATAACAGTCTCAACTATGT ACTCATCACACTGGCACATGCCCCCATGGGGAAATAGGGCAACACATTTCAGGGAAAGGT ATGTAAACTGCCCTGAAGTTCTAACCATCTTCCAAATGCTTAATCCTCACAAGAAACCCT GAAAGTACTTATCCTAATTCCCATTTTATGTTTGGGGAAACTCAGACTCAAGGAAGTTAG GTAGTTTTTCCAAAGTCACTAAGCCAGAAAGCAGTGTGACTGGGATTATTGGAACTGAGG TTAAGTTAGGAGGGTTAAGCTCTGTCCTGCCAAACCCACTTCCAAGTGTGTGCAGCCCAG GAAGGCCCCAACTGTTGCAGTTACAACAATGTCAACCCCCTCATCCTCTTCCATCCATTC ACACATTGCTTGGATGGAGGTGGTTTGAGCGTAGACAATGTGGGTTATGGTATTGTCAAT ATGGGCTCAAGACAAGGAACAAAAGGGAAAGAATGTATCCTATAGCTGCCAACCATGGGA ACTTAAACACTTTTTTTTTTGTTTTCAGGGACCTGGACAAGTTTATTTATCTGTTAGATT TCAGCTGTGCCTGGTTCACCATTCCTGGAGGGATCCCGTCTCCAAACTAGGAGCAGCAGC AGAGAAAAGACCAATGACAAGGAAACCTGATTCCTAGTCCACACAGTGGGCCCAAGGAAG GGCTTTTCCTAGCTGATCTGCTCAGCAGGGTATGTGTCTAACGCCCACCAGGAAGTGAAG TTCACACTCTCTGGCTTGAACATCCTGAGGCAGCACAACACAGTTGCTCACGTTGCTTGG CTTCAAATTCCAACTCTGCCACTTACCAACTGTGTGGCCTGGGGCAAGTAACATACCCTG CTTGTGCCTTAGTTTCCTCATCTGGAACAGAGAGATAATAATAGGACCTGCCTATAAGGT CTTCCCCTCTCTCTAGCCTGGGAGGTCCTGGAGGCACCTCATTATCTTTGCATCTCCATG GCCTAGCAGGGTGAGAGAAGTCTCCTGGGTACTCCCAGTGGCCCCCTCACAGCATTCCAC CAGCTCCTCCTGGCGGTGTCACTCACTTGATCTTGGCGTGGGCCCGGGTGCTGGTGACCA GCCGGAGAGACAGCTCATTCTCGTAGCGAGGAATGTCGTCACAGTACACGGCCTCACCAG AGGCCTGCATGTCCGCTGCCAGGTGGGGCAGGGGCCGGCCCACCATGTCCTCCTCAGACT GACCCTTGGGCACCTCCTGGAATGACAGGGTCATCAATCAGGGTGAGCTGCCAAGGACAC TGCCCCTCTATGGGCCCAGGGGACACTGGTGAGCTTCATGCTACATGGCAAAGGACACCA AGGGGTAAGAATAAAGAATTCAGAGGGGCGTGGGGCAAAGGGAACAGGAAGGTGCATAAG TGATAGCAAGGGTGGTCCTAGTGTTGTTATATAAAAGAACAACAAGAAAAAGAAGAACCT ACATTTCCACTAATTGGGGATTGGGTAAATAAATTATGCAGCCCCATATAACACAATAGT ATGCAACCATTAAAACATACTTTTGAAGAACTTTAATTAGAAGGATTGTTCATGCAAGCA TAAAAACGTGACGCAAAACATTTGTGTTTGTGTTTGACAATAATTCAATTATGTAGGAAA AGATAATATATGCTATAAATATAGTATATACATGTCCATATACACATAGGAAATAATGAA AAGAATTAAACAAAAATATAATAATAATTTGCTCTCGGAGGTGGAATTTTTGGTGATTTT TATTTTCTTCTTTATGCTTTTCTGTATTTTCTAAAATGTTTTAAATTATTGATCTCATAA TAAAGTTCTGTTTTTGTTTTACAAAGTAATCATAACAATGGCTAATGTTTATTGAGTGTT TCACCATATCCCAGGGACCATCTAAGCAATTTACTTTTATTAACACATTTAATCCTCAAA ACCATCTTATGAAACAGGTATGTGATTATCCACATTTGCAGGTGGGTATAATTAACTTGC TTAAGAGGCACACAAGGGAATAAGTAAGTTGTTCAAGGTTGCACAATTAGGAAATGGCAG AGTGTGGACACAAATTCAGGCAGTCAGGTTCCAGAGTTCATGCCTGGGACGACTACACTC TAGTGTGCAGGGGGCAGTAAATTGTGGCATGGGGGCCAACACAAGCCCACTGCCTGTTTT TGTAAATAAAGTTTTATTGGAAGGCAACACACTCATTCATTCCTGTTTTTCCTGTGGCTG CTTTTGTGCTACAATGACAGAGTTGAGAAGTTGCAATAGAAACCATCTGGCCCACAAAAT CTAAAATGTTTTCAGGAAAAGTTTGCTGACCCTTTACGTAGCACCTCTCAAAAAGCTGGA GCAGATAGATGGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTTAGCATACTCAAG AAGACGTCTGGCTTTGTACATTATCCATCACGTAAAAAAAAAAAATCTGTAAGGAAGAGG GGCAGCTAAGAGTTTAATCCCAAAGAGAGAAATTTAGGCAAACAAGGGAGAAATAGTGAC ATTAACATCTATACGATTCCCATTTTCTTCACTGGGTATTTACGCACAAGAGTAAGGAGT TTTATGGACCTATATACAATTCAAGTTAGTCATTAGCCGATGGTCAGCCACTAGCCAACT CATGTGGCCTGCAAAGTCCCCTGATATTAGCCATACACTGACCGTACTCACTTGGAAGAG CTGGACATCGGCTGGGGGGTCTTTCTGAAACAGTAAAGTTGCACTGGCGAAAGTGGGGTC CAGTTTACCACACTTCTGTGGAGACAAGAAAACAGAGGTGACCAGGATTATATTTCAATC ACTGATTCCTTCCTTGCTTGTCCATAAAAATGACCAAACTGATAACTGATCCCCTTGTCT CTTCACTTCATACGCCTTTGAGTGCTGGCTGGATCTCTCAGCATCCAAACACGGGCTCTG AGAGCTCAGAATTTAAGAGCAGCCTCAGCTTCACTGCTAGCCCCCCAGTGGACCCTGTAG ACTGAATGGTCTGTACTTTCTCCAACACCCCAAACTCTTTCCCTCCTTCTTGCATTTATG CCTGCTGCTGTCTCTGTTGGGAGTATCCTTCTCCTCCTTCCTTGCCCTCCTCAATTCTGT GGGAAGCATTTAATGATATGGAAAATGTTCACAATATAATCCCAATGGAAGCAAAGGGGG ATTTAAAGCGCTATATGCAGTGTGGTCCCAAGTCTATTTAGAAAATAATATATCCACATC AAAAGATAGGAAGATGACAGATATTGATAGATGGATGGAAGGACAGATAGAAACAGAGAG AGAGAGAGATGGGGCAGACAAACAGTATGACAGATAGATGGACAGATAAATGCAGGAAAA AAAATCAGAGGAAATAACCAAAATACTTGGCAGTGGTTTTCTCTGGGATTTGAGAGTAAG AGTAATTTTAGGTTTTCTTTATCCAATCCTGTATTTTTAAAGTTCTTTTCTTAAAGAAGG ATTTATCTCTGCTGTCCCTGCATCAGTGACATCCTCTCCACTTTGGGCTCCCTCCACACT CCATCTCTGCAGTTGTCTCCCAAGTGTGGCCTTTATTGTCCATGTTCTCCCCGACACTGA GCTGCCCCCTAGCACCTCATGCAACCTGGCATAGGATAGGTGCAAAATAAATTCTTGGTG AACAAATCTCAGGAGCTGGGCCCACCTCAGCCTGCACTCTCTCTTGAAGACATATCCTAT GGATTCCACGGCCTCCTGGCTATTGCAGCCCCACCTGACATTCCCATTCCACCCTACATA CTCATCACACTCTGCATTCCCTTTCTTTTTTTCCTTTCTTTCTTTCTTTCTTTCTTTCTT TCTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTCGCTCTTGTAGCCCAGGCTAGAGTGCA ATGGCATGATCTTGGCTCACTGCAACCTCCACCTCCCGAGTTCAAGTGATTCTCCTGCCT CAGCTTCCCACGTAGCTGAGATTACAGGGCAAGAACCTCTGTCGCCAAAGCCCAGCCCAG CACTCTGCCTCTAAGCCAGCTGGTCACTCCCATTTCCAAGATTCTTGTGCTGTGACCCTG GTCCCTGCTATTCTGCCCTCAGATGTCCAGAGGAGAGGAGCAAATTTACTACCCAGACCA ACTTCTTATATCCCCAAACATGCTACAGAGAGCCTGTGCCTGGCCAGGCCCCACTCACGT CTTCCAGGTTCTCTTGGCCCAGCTTCTGAAGGACTGTCAGGTAGAACTTGAAGAAGAAGC TGAGGGTGAGGGTGCACCGGAAGTCCACCATGCCACCAGGGGCATCGGGAGGCAGATGCA GCTCCTCTGCCAGTCCTGCACACACGTCCTGCAGCAGCTCCTCCTTCCAGAGCCTGCCAG AGAGCAGGGCGTGGGACAGCGCTCCCGCCCAGCCCTCCAGACCCCTTTGTGTAGAGCTGT GTGCCCAGGGCCTCGGAGCTGTACAAAGCTTGGTTCAAAATTTGGCTTGGATACTTAGAG TTGGGTGACTTTAGGCAACTTTAATTAATCTCATTGAGCCTGTTTCCTCATCTTCAAAAA TAGATACAATTTTAAAAGACCACCAAAATAATAACAGTTAAAATCTATCAAGTCCTCACA ATGTGCCAGGCAACATCTTAAGTGTTTTATATGAATTCTCACTTTTAATTTAAATTTGAA AATGTAGTAAGCAAAATTCCTACACCCATTTACCAATGAGAAAACTGAGGCACACGGAGA TTAAGTAACTTGACTTATGTTATCTATTTGGTAAATGACAAAGCCAGGAATTTCGGAACC AAGGAACCAAACTCCAAGTTAAGCTTTATTGATCCTATGTGGGTGCTGTAAGGATTTCCT AGGATAATGTTAGTGAAGTGTTCGGTACAATTTCTGTTATATAATAACCATAGAAATAGT AATAGTAGTAGCAGTAGTACTAATCACAGCCATAGTGGTAGCAATAGTAGCAATAACAGA GCAGTAGTAGTAGCATCAGCATCAATACTACTAGTAATAATACTAGCAACAGCAATAATA GTTGCAGTAGTGGTAACAAGATAGATAGTAGTAGTAGAAGTAGTAATAGTCATAGAAGCA GTTGTCATAGAATCAACAGCAACAGTAGTAATAATAGTAGTAACAGAAGCAATGCCAAAA AGTAGCAGTCATAGCACCAGCAGCATCAATAACAGCAGTAATACTACTGTTAGTAGTAAT AGTAGCAGCAGCAATACTAGTAGCAATAGTAATAGTAGTAGTAGTAGCAGTAACAGTAGT AGTAGTAGTAATTTCAGTAGCAATAATATTAGAAGCAGTAATGTTATTAGTAAAATACTA GTATAACAGCAGTAATAGTAGTAGTAGTACTAATAGAGTAAGCGGTAGAAGAGGCAGCAG TAGTATTAGCAATAGTAATAGTAATAACAGCAATAATACTAATCATAATAGTGACAGTAG GAATTGCAGCAGTGATCATAGCTGCAGTGATAGTAGTAGCAACAGTAGTCATAGTAATAG CAATAATGAGTAACAGTAGTAATTTTAGTAGAAGCAGCTGGAGTAGTAGCAATCATAATA TTAATTATAGTTGCAATAATAGTAACAATAGTAGTAGCAGCAATGGTAATAGCATAGCAG TGGCAATACTCCTAGTAGTAATACTAGTAGTAGTATCGGTAATAGTAGTAGTAGCAACTG TGGTTATAGTAGAAGTAGAAGTGGTAGCAGTAGTAGCAGCAGTAGCAGTAGTTATGGTAG TAGTAGCAGCAATAGTAATACTACTGGTAGTCATAGTAGCAGCAGCAGTAACAATGATAC TATTAGTAGCAGCAACATTAGCAGCAGTTTCATTGTGCTGTTAGCTCTTACTTGGAAAGC TGCCTCTGAGTGGTCTTGAGGGCTGAGATGGTTCTGTTGGCCATTCCACCATAGCAAAGG GCCAGCTCCTGTACCTCTGTGGTTCCTGGCTTGAATAAAACTCTCATGCCACTGGTTACC TTGGCAATGTCATCTTCTCTCCGGGAGGCCTGCTTGAATGCTGAGAAATACTCCCCCTAA AAGAGATCAGGAAGGTGCCTGTTTTCCACCTTGCTCTGTAGGGGCTGCAAATGGCAGACC CAAACCACAGGGCTATGAGGTGAGGTGAGGGGATAACACCATCACACATCAGTGGGTGAA CTGGCCCCGGGAATCAAAGATCAAATGTAACTGATTACCACCTGTTTAGGAGAGGTTCCA GATAACATTCCCAGAAGCTGAAAAAAAAAACAGGATTTCTCCCTGCTAGTCAGAAAAGCT GAGGGTCAGGGACAAAGTAGAACTGGGTGGTCTCCATTGAACAACAGCTGCAGGGGAAGA AGGGTGCTTTCACAAAGGCTCCTTAGAGACCCCTCATCCCCCTTACCTTCCCTACCCTGG TGCCCACTATCAGTGCCCACCCAGCCTCTCTGGGGACTGAGGCTGTTTGGCCTTTGGCAT CCTCTGTTTGTGGCCTCCACAGTGCCCTCTCTAACCTGCCTCTCCCACCAGTCTGTTGGC ATCGTTCAGAAATCTTGGTGAAAGAACCCGGGCACAGTGGCTCACGTCTGTAATCCCAGA GGCCTAGGTGGGAGGAGTACTTAAAACCAAATGTTCAAGACCAGCCTAGGCAACATAGTG AGGCCCTATCTCTACAAAAAAAAAAAAAAATTAGCCAGGTGTGGTGGTGCACACCTGTGG TCTCGGCTACTTGGGAGGGTGAAGTGAGAGGATCACTTGAGCCTGGGACATTGAGGCCAC ACTGAGCCGTGATCATGCCACCACACTCCAGCCTGGGCCAGCAGGCAGAGTGAGAATCTG TCTCAAAAAAAAAGAGAAGAAAGAGAAAGAAAGGAAGAAAGAAAGAAAGAAAGAAAGAAA GAAAGAAAGAAAGAAAGAAAGAAAGAAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAA GGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGCAAGCAAGCAAGCAAAGCAAGAA AGCAAGCAAGAAAGAAAATATCACTATCACACTATGAAACAATCACTGCCCTTGTGCTTT AAACACATTTTCCTTCCTGGGTTCGAGCCAGGATCTTTCTTTAAGGATAGGAGGAGAGCA TGAGCTATTTTCCAGGAAAGAGCCACCTGACTTCAGGCCCTTTCTGTGTCAGGTTCCTTT TGAGGTCTGTACTCACTCTGGCACCACAAATTCTGATGAACACCAAAATTAGCAGGTTTA GGGAGAGGAGATCTATTGGAAAAAGCACAATGAGGCCCACAGTTGAGGCCCCCAAATGGC CACCCACTTTTCCCTGAAGAAGCCATGGAGCCCGCTCCTGATGATAAAGCTAGCTCAGCT TGCATGTCATGTGTGGCTCTGGGGCACTGAGCCCAGAGTTTGACCTTTGTTCTGGAACAG AGGTCCCAGGTGCTCACTCCCAGGACTGTGCCCATCCACGGGGACATTCTCGCTGGGGTA CAGTGAACTGTCAGTGTCAGGCTGACAATACCCTTTCTTGAGAGTTTCTAATTCTGGGTA TTAAAATCTCCTTTCTTTCATGGAAGGATGTGTTTTGTTAATGACCATACCTGGCAAATA AAAACTGAATAGAGCTACACCTGTTTCCTCCCCACTTTCATCACTCATAATTAAAAAAAA AAAGTTTACTGAACTGTGAAATTCAAAACTCTGGGAATCACTGCTCAAAATGGTCTATAC AGACAAGCTAGAAAACCATTAAGAAACCACCTCAGGGATATAAATGCTCTAATTTAATTA GCATTCTCATTAAGGAGGTCAAAATTACCAAGGGCAAAACATGCCTTAGAACACTCACTA AAGCTCCAGCTGTGGGAAACCTTCACACTCTCTCTGACAGTGGCTCCCCAAGCCTCTCCC AGATGCCTTTTCTGACAGGCCCTTTTGGATGTGTTCTGAGCTGGTAGCTGCTAAGGGAGG AAAGACCCACACCAGGTCAAGACATCACAGGGCCCAGGGAACAAAGAGGAAGGCAGCCAG TGGTGCCCAGACCTGCCCCAACAGGCCAGAAGAGCCACTCATGAAGCAGGAATCCATCCG CACCAATCCACAGCGAGGTCAGTGAAGCAACACCTCGTCAAGCCTAAGGTCAGCGTATGA GGGTCTGAGCCACAGGCAGCTTCTTCATGCAGCACATGAACCCCACATTCTTTACCACGG GAAAGCAAATTTCCTCTGACATGGGCAGGAATCCTCGACAGCTAGATGTGTTCTTGGAAT TCTGTTCTTAGCTGCTGGTCATCTCCACTGGCTTCTAGGCATCACCAGGAACCTTATGAA TTGTTTATTTTCAGTCCTCACAATAACCCGTATAGTAAGTGACATGGTGCCCATTTTACA GATAAGGGAATTGGGGCTCAGAAAGGTGAAATGGCTCACTCAGGACCAAGTTTCTAGCTA TCTGGTTCCACAGTCCATGCCATGTGGACTCCTATCCTGCAACTTCTCATTGTCCAGAAA GGAGTATGGTTGGTTCAACAGAGGCAAAGTTCAGAGAGAAAAATCATCAATGTAAAGGTT GAGAGATGCTCAGGTTGGTCCCTGAAGCAGATTCTGATCTCTTTGTCTAGAGCCTGGCAA TAGGACTTATTTGAGCAGAGCCTGGAACCACTTCCAACATCTCACCTCCCTGCTGTAGGG GATCTCTATGGAGAGCAGTATCTCCTCCGGGCTCAGCAGGGTCTTTCTGTAGCCAGGGAA GAAGGTGTGGTCCATCTGGACAGTTCTCCTGGTGCCTGTACAGAAGCAAGATGAAGAGGA GCCAAAGTGAGGGAAAGGCTGGGAACCCCCCATGGGGAGAAAGGATAACCATCAGTGGGA TTCTTCATGCTGGTCTCCAATGCCCACAGTCAGAGCAAATGACTGGCACAATTGGGGCCA AATCCTCTCTCTGAAATCCTTAAGCATCCTTAAGCAATGGTGTGCTGGTGAATCTTTAAC AACCAGTTCCGTGTAGGGGGAAAAGCCCTGGTTTATAGCATTTGCCAATTTCTGTGGTGT AAATACTTCCAGGCCACCAAAGTTGCATCACTGAATGTGAAGCTGGGAAGAAGGCAGGAA AGAGTTAGCACAGCAACCCGGACTGCTGTCCTCTGTAGGGGTTGCTTACAAGGCTGGCCC TTGGGAACTTGTACTTCAGAAGGGTTCCCAGTGCTCCATGATGGAGCAGCTCACTGCGCC TAAATTATCTGTACAATCAATAGTTTATGCTGAACCCCTGCTTTCCTTCTGGGAGTCCAG ACTTTAGGCACATGCTAGTAGAGGCTGCCTATGTGATGAGCTCCCAAGAAAACCTCTGTC GCTGAGCCTCTAACAAGCTTTCCTGGTAGGCAAGGCATCACTTGTGTTGTCACAACTTAT TGCTGGAGGAATTAAGCATGCACTGTGTGGCTCCACTGGGAGAAGTCTCTGGAAGATTGG ACCTGGTTCCTCCAGACTTTGCTCCCATGTATCTTTTCCCTTTGCTGATTTTGCATCCTC CTGCTATAATAAGTCATAGCCAGGAATATGACGGCATGCTGAATCCTCTCAGTGAATATC AGAGCCGGGGTGGTCTTGGGGACCCTCTGACAAGGCAGAGATGCACTGGAGCACATAATT GTAGAGCATTTCCACCGTACAGACAGAACAGATGCAAATAACTCCAGGAGCACTGATAAC AGCAAAATGAAGTACTTACGAAGTGATGAATTTTGAGTATTTATTCCTTTTGTTTTGAAT ATAATTTATTTCATTGTAATTTTATACAATTTTATTTTTATTTTTATTTTTTGAGACAGG GTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGAGATCTCGGCTCACTGCAACCTCC GCTTCCCAGGTTCAAGTGATTCTCTTGACTCAGCCTCTCAAGGAACTGGGACTAAAGGCA CACACCACCACACCCAGCTAATTTTAGTGTTTTTAGTAGACATGGGGTTTCACCATGTTG GCCAGGCTGGTCTTGAACTCCTGACCTCAAGTAATCCTCCTGCCTCAGCCTCTCAAAGTG CTGGGATTACAGGCATAAGCCACCGCACTACCGCACTTGGCCTGATTTTTATTAATAACT GTGTTTCACAAATGGTTCACAGAATTCCTGAAGATCCAACAGCAGGCTGTGGTGAGCCAG TGCATCCCAGCCCCAGTACCCCACTAGGTAAGGCATGCAGGTAGCAGTTCCTGCTGTGAA TTCTCTACAGAGAAAATATCCAGCTTTCCCGTCCACCAAACCAGGTACATTCTCCATGCT TCCCTGGATCCAAATCACAGGGAAAGCTGGGTCACTGAACTTTGAGCTCTGTTTCTCCAG AAAATGACCTATCTGGTGAGACTTTTCTCCCCCAAGTCCTTCTTCCTGGACCTCTGCTTC AGGCAGCTCACCTCTGGACACAAGTGTCAGCTTGGCCCCACTGGCCATGAACACGGGGTT GAGGTCGGAGATGGGGCTGGCAGTGATGATGTTCCCTCCAACGGACTAAAACAAGCAGAG AGCATGCAGTGAGAGCCCACCCCAGGAAACCCCTGCTCACGTAGCAGGCTCCTGAACATA CCAGCCAGGTGACACCTGCTGCAGGCAAACCCCTGAGGTCCTGTGCCTACTGTAGTCACA ATACCAGCATAGTGAGAACTTCGGCATTCTGAAAAATGCGCAAAATTTGAAATCAGAATA CTTGAGATTGGATCCCCACTCTAAAATTTTAGCAGGCAAGCCCCTTTAAGTGTGTGTGTT TGATTGATGATTTCACCCAACCTTTTCCCGAAAGGATTGAGGTGATTTATCACAGAGGCC ATATAGACTTAGTAAAATAGAAGATAAAGATCAAGGAAAGAGAGGAGGAAGACTTAAGGT TGAACAATTTGCTCTATTTGGATCTGAACTTCCTGGTAACTTGGCAAAAAAAATGTAAGA AGAATCAGATACAGGGTTCTCGTTATTAGAAAACAGGAAGAAAATCAGTTGCACGATGAA AATACAATTCTTCCTGGAAATAGATTTTAGCAGAACTAGGGAACTCAGCAGAGTTTTTGA GTTTATGTTTCCTTATCTACAGTTTATGTTTCCTTATCTATAATCAGAAGTGACAGGTAC TTGGGGTGGGGGCTGGGAGGAATAGGAGTAGGCTGTTTTGTTTTAATTTAAAAAAACAAT TTAAAAATGGAAGAGATAGCTTTTCTTCCGACACCATAAACTGTTGTGAAGAGCTTCCAT TGGCATAGGGTGTTCGAATGCCACCATTTGCAAACTGGGAATGTGGGGACTTGTCTGAAG GCTGACTGAATAATCAACAGGTGTATTCCTCCCTCTGTGGGAGGGCTCTGTCTCTGGTTC TCCCTATAGCTCTGAAAGGAAATTCCCCTCTCAATTCTGACTTCTCCCTAGCATATCCAT ATCTCTTGTTCACCTACTGTTTGGCTCAGCCAAGCTCAGGAAGGGGGAGGGAGGCAGGAA GCCTCATCTCTGCAACCACAGAATGAAGCCTATGAGTCGTGGAGTGCATTTCCCAGGGTG CCCCACAGACCACCTTCATCAGAAGCACCTGAAGAGCTGGGCTACATCCCAGACCCATGT ATCAGAATCTCTGAGGGTGGGGCCCAGGAATCTGCACTTTAACAAGCACTGCTCCTCCCA GGCAACTCTAAGCGCTAAAGTTTGAGGCCCACTGCACTGACACAGTGAGAGTCTGGCTGC CCTGCTTTCAGATGAAAGCTCCATCCTACGGGCCTCGCTTGCTTCTGAGAGCGACTCACC GCCACAGACTTGACTTGCTTCCCAGCAAACCAGCGCAGCTGCTCCAGGACCCCTCTGAAC ACCTCTGTCTTTTGGGCAGGAAGCTTAGCAACAGCATCCACCAGGGTTTTTTCCACAATG CTCAGGGGGCAAGCAGCTCCAAAGGAGATACCTGGGAACGCACGTTCGGAATCACAGCAA TTCTTCCCACAGTTCAGAAGAGGCTTTCATGCACAGCTCCTCTGAAGCTTTCCAGCAACT GGAGCAAGGCTGAATCAGGACTCACAGCTTTCCATGGATGAGGAAATGAGGGCCCAGAGT GGTTGAGTGACCTAACCAATGCCACACAGCTAATAAAAGAGCCAGTACTCAAGCTTGGGC CTCTTGATCCTACAACCAATGCTCTTTCCTCTAAACCAGTAGTTCTCAACTCATTAAAAT CAGAATCTCTGAAGGTGAAGTCCTAGCATTCTTTTTAAAAGCACTCAGGCACAATCCCCA CCTCCCCACCCCCGCATGAGTGATTCTAATGTGTAGCCAGAATTGAGAAAAATGATTGAA GATCCCGCAGCCTCTTGCCCACTGGCACCCTACCATGGATGTTTCAGCAATGAATGGGGT CTCCTCCCGCCTTTCCCTGTGCAAGGTGAGCCCCAGGAGAAGCAGGGGGCAGCCAGAGCC AGTGGGGAGACCACCCTGATACCTGCCACCCACCTTGTAACCTATCCCCAGCCTCACAGC CCCTCCATAAGCTTGGAGTGAACCTCCTCTTACCGTCGGGTCCATGTTCTACCGAATTCA GCTCAGGGATCCAGGCTGGGCAGACAATCATAGGAAACAGCATATTCTTGAACTTCATCT CAATGCCTAGAGAGAAACAAGAAGCTGAAGTTGTAGGCCCATTGTTGTATCACCAGGGCA GGCCTTAGCAGCTTTTCTCACCATTACACACAGGATATATGACATATCCACAATCATAAT ATGCTCTCTGGTGACTGTAGGTGTCTGGGAATAGGAAACTCAGTAGACCAGGGGTGGGAT TAGATGCAGTCTTTGGACTGTCAGCCCAAAACTAGGTCTTTCTTTCCCTCTCAAAAAACC TACCTGAATTCAAATGAAATGAGTTTGAATTCACTCTAGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTTTGTGTACATTAGAAAACACAGGAAATTAAGGTATGTCAGGAACCC TTCTAAGCACTTTCCCTATTTTAACTTAATTAATGCTCACAACAACCCTATGAGGTACTA TGATTTTTCTGTTTATAGATGAAGAAGCTGAGGCACAGAAAAGTTAAGTTTCTTGCCCAA ATCACACAGCTAAGAATAACCAAATTTCAGTACTGGAATGATTATTCGTGTTGGGGTATA ATCGTAATAAAAACATGAAAGTTTAACATTAAAACAAAAAAGGAAAATGGGAGGGAAAAC TTCAAATCTGTCCTCCAGTTCCCACTATCTGCCTGAGTTCTTCAAGTTGTCTGGCTTTGC GGGGCCACACATCTGTGTGTGGTTTCTGGCCTTCCTGACTAAATGAGTCAGAAGCCTCTG TTAAACAAGTGTGCCTCTGTTCCTTAGACCCAGTTGGCTCAGCACCTCTCCCAGCCCTGC CAACAGTGTATAGATGGAAAAGGTTAAAAAAGAAATACCTGTGACCTCTTTGCCCCCCCT TCCCCCCAGGTGCTGTTTAGGATTTCTGAAGGGGGCCCTAGGCTTTGTGGATCCCCAGAT TCCAGAATCTTCAAAGCTCCCTTCAGAAATCCTAGAAGCACCTGAATACCAGCCCCTTTT GAATATCAGCTTCCAGGACAAAGAACACAGATTGAAGCAGCAAGTTCTACGTTACTAAGG TTTTCTCTTTGTCTGCCTTCCCCCAACACTCTGCGTTGACTGGAGGTGACTATGCTATTG GGGTATGTATAAGAGAGAAGGGAGTGGCGCAGAAGGAAATGGTCTTGAGAAATCATTTCT AATTGTGGAACTTAGGTAATCTTTGTTATTCATTTCTCTTGGAATCCAACTGGGCCCAGG ACATTGGATGGCTCATGGCAGGGAGCATGCAAGTGTGAAATGATCCCCTTGAGGCTGGGG TGGGGGACCACATGAGCCCATGAGTTTGAGGTGAGCTATGGTGACATTGCACCACTGTAT TTCAGCCTGGGCAACAGAGTGAGACCCTGTCTTTGAGGAAAAAAAAAGAAGGACCTCCTA AGATTCCCCCAGCCACCTTAAATCAAGCTACACCTGAGCTACATGAGCCATGAGTCCTGT TGAGCCATGGCCATCAAGATCACATTTCTTGAGGTGTGTCTCAGCCCACCCTGCTGCCTC AGTGTGTCACAAAACCACAGTTGGGGACTCTATCTTATGTATATGTGCGCACGAGGGAGG CGTCCATTCTGACTCCATCAGCACTGACCCAAGCCAGGCTCTCCTCTCTGTGGCTGAGGA GCCAACCAGAACTCAGGGCTTGGCAGCTCCTTCAGGAACCAGAGCCAGGACCTGACTGCT TAGAAGGAGAGCATGCCCCTCCACAGCAGAGGTCCTCAGCTGTCCCACGGTCTCCTCCTT AGATCCTCACTAGGCTTGGGATCCAGCAAAGTAGAAATAGGCCATGCCAGGTTTAGAAAT CGACAGAGATTAGCAGGGACCTGGGAACCTCTCCCCATCTCTTACAGCACTGGGGCTGAG AGGTGCATATTCTGAGTCTCCCAGCCTGTTCAACTATTCCAGGCCTCACGTCCTAGGTGG TAGCACTGACAGGGCAGGTGGCCATGGTCATAGGCAACACAAACACAGTCACACCTGGAG CTCTCCTCTTCTTTACCTTATCACATCCTCCCCCAGAAAAAGTGGGGTGGTGGGGTCAAA AGCGACATTTATGGAACCTCTAGTGTCCATCAGCCACTGGCCTAGACACTTTGCTTAAAT TAGTTCCTCCTCCCTTAGACTAGAAGGCCCTTGAAGGCAAGGAACCATGTCCAATTGAGC TTTGTATCCCAAGCCCCTTCCAGAGTACCTGGCTCATGCTCGGTGCTCTGTAAATGTTTG TGGAGAGAAGTCAACTACATGCAAGGATCTCATTTCACACCCAAAACAATCCTTCAAGGA GTTGTTAGTATCCCCATATAAAAAACAGAAAATGAGGGTAGATGAGGACAAGCAACTTTT CTGAGGTCACACATCCAGCAAGGGGCTGAGCCAGGCCTGTGGGACTCCACAGCTAGGGGC CTTTGCAGGAACTGGAGTGTCCAGGGATTTCCAGTGGGCTCCAGGTAGTCAGTGGGGCAG AGGGATAGGGTGCAGAGGCAAGTAAAGTCAGGGGGAGGTGAGGATGGGCAAGAGGACCTA GAAACACCCCCAGACCCCCTGGCAGCCCCAGGGCAGCCTCCCTGGCCCTTACCAATCTCC GTGTTCCCCACGACCAGCTTGGCGTCAGGGTGCTGAGCCTTGAGGTCCAGCAGCTCCTTG AGGGTTGAGGCCTGTATCCACGTCACACGCTCCCCTTCAAATCGCAGCTGCTTCCGAGGA GTGTCTTTCAGCCTCTGGGAAATGCAGTTTTCTTACTACACTGTCTCCCTCTTCCTACTG TCATTCCTCTTATAAATTGCTTTAAGTCCTCAATGGGATGTTTTACTGACATTCAGAATG AAAATATCTAACAGGAAGAAGCAAGGGGAAGTAATATGTTCAGAGGCAGGAACTCCATTG GGACTAGTCTTTACAAGACTTCCATGAAGGAGGCATTATGAGCCTCATTTTCACCAGTGA AAGAAGATCCTGAGGGTCAAGGAGGTTATGGGACCTGCTGAAGGTCACCTGCCATGAGGG GTCCCCAACAGACCTGGCTGAAAGCCAGATTCCTTGCAGTGCCCCATAATATCTCCAGGG GGCACCATGGACAAGGCATGAGAAGGGAGGGAGGGAGGGAGAGAGGGAGGGAGGGAGGGA GAGAGGGAGGGAGGGAGGGAGGGAAGAAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGA AGGAAGGAAGGAAGGAAGGAAGGAGTTTGTTATAAGGGGATGCCTAGGAAGGCTGGCTTT AGTGCTTGCAGGAAGACACTGGGCTGAGAACGAAGCCCTCAAATCGAACTGCCAGTATTT TCAAAGTTTCACAGTCCAGAGAAAGATCTGCTGGTGGCCTGCTGCAAAGCCATTCTCTCT GGCCTGTTGAAGCTACAAGGTAGTTTTCATAGCTCAAAACTCTGAGAAGTGTGCACTTCA AAAACTCCGAGTGGCTTGATTCTTTCGTTGCCATAAATATTAGAGTGATGGTGATAAAGT GGGTGTGAGGGGGTTTCCTTAAGACAGAGCTGTGAGCTGCAGATCATGTCCTTTGAAGAG AGCTCTCGTTTTTTGTTTTGTTTTGTTTTGTTTTAAATAAATGGATTGCTTATAGAGGGA ATACGTTTCTTGGAGTGCTTATGTATTAGATATAGGCAGGAGATCAACAAATGGTTATAG TGAACCTGCTACACTACACAGTGTGCCTAGAGAGCCAGTCCCTATCCTCATGGGGCTTGT CATTTAGCAAGGAACACAGACATCAAATTAATAACTGTAACTGTGACACACATGAACTGA AGTGCAGGGGCTGTGGGTACACATAGCAGAGACTCAACCTAGGGGAGTGTCAGAAAATGG AAGGGAAATTTAAGCTGAAACATAAAGGACAAGAAAGACACAAAGTTCCCAGTGGGTATG AAAATAAAGCAGGTTTCCAGGGACTCACAGTACAGACCCGGCTGGATCTGTCCCTGAGGC ATCACCTACCAGCAACTCTGGGGGAAAAATGGGCTCCTGGGTTGGATCCAGGGGCGTGAA CTCCTCTGGTTTGAATAAAGATGGCGAGAGGCTGACCTATGGGGAAAGAGAACAGGTAGG TGATGCAGTATCTCCTCCTTTCAAACACCCAAGAGGACCAATTCAGCCTTTCCTTCCAGC AAGCTCATTCCCAGCCCCCTGCAGGCTGCAAGAGGAGCAGGTAATCCCTGGGAGGCAGGA ATGAGAGAGTCTCAGTTACAGGACCCGGGGCTAACGTGCACCATCACCATCCCCACAGTC TGCCATCACCGACTCACCGTAGGTTCCTCTTCCAGCCCCCACCGCCAGGGACATGGAGCT CGTGCACTGACTCCTCTAAGTCTCAGATTACCCCCAGGCTTCCAGGGGGAGAAGAACTCA CTTACTGAGTGGTCTTTCTTCTGGTTCATGCAGCAATTTGGATTATTCCCATCTCCTCCA CAGCATCCACCATCCTAGAGAGATGATGAACATCTGCACAAGGGTATTTACAAAGAGTAT TTGCAGAAGCTAAGGAATCTAGATTACTAATATCCAGAACACTCCAGCTCTGACGCCTGT CCCAGCATCAACAGCAGGGGCATCCTGCCTGCCTGTTGCCCAGAGTGGAGGCCTCCGCTA CATTCCCTCTTGCTTGGCTAACGTAGATTAAACAACTCATGGATAAACAAATAGGAGCAA CAAGGCCACTGAATTTCAGGAACTTTTCTCCATAAAAGCTAGGTCCTACTTTATCAAAAC CTATCCCTTATGCCCATTTCTCTTCTTCAGTGCTGCTTCCTCAGGAAGCGTCTATGAGGG ATATTCCCATTGGCTCTCTCAAGACTCAAGAGGCTTGACTTCCAGATCAGCAAGGTTCTA GGGGCGTGGCTGGTGTCTCCCAGGCTGGGCTCTCTGCAGGACCCTGCCAAAGGATGTCCA AGACGGGTGCTGAGCCCAGCACTGTGTCCAGCCAGTGTGCCCAATGGCCTCCCTACTGCT TATTAGGCACTTCTTCCCAGAAAGGTAAACACCCTTCACTCCTCACTGTGGGCCTGTTCT GGAGAAGTATGCAGGTCAGACCACCCAGCATCTCTGGGAAAAGACTTGCTCAGGACCTCT TAGGATACCAGTGGCAGAGCACACACAGAGTCTAGAATCACTACCACCCAGCACCGAGGC ACTGCAGGGTGGCAGAGGGGCGCACTCAGCTGACTGATCTGCAGCTCAGGGCTTCAGAAG ACAGAGTCCTGGAGTTGTGCTGAGATGAAAAAGTAGGGGAAACTCATAGGTTCTGCCTCA GGCACTTTTATCGGGTAGTCAATTCCTGAAAAAGCAGGCTGGGAGCAGTCCTTCTGCAAG TCAGCCACAGGAGACACCATGCCATGCTGGCATTTTCCAGAGTCTGTTTCACAACTCGTT GTCTTCTGCAAGAAAGCACTCATGGGATGCTGGAGGTGTGACCTTGGAGAAGTTGTAAGC AGGCAGGCAGTGGCATCAGGAGAGAAACACCCCACCCACCCCACCACCTGGACACGCTGC TCCGTGTGCAGACTCTTCCTGCATTCACAGCTCCAGCACTGGACACCAGACCTGCTCCGT CCATTCTGAGCCTCCCCCCAGCCAGCCACCTTGCACTTCCCCTCTATATTTAGAAAGAAA GAAAGGAAGAAAGAGAGGTTTCTTAGTGCCTTTTCTCACCTTTCTTCTTGGAGAAGGAGT GATGTAGGGAAATGCCCTGGCCTACCTGAAGTGAAAGTCCTGCATCCCACTCACCTGGCC CTCTGAGGAAGGACATATTTCACAGAAGCGCCTTTTCCAGACAAAGTGCCAGTGCATTAT TACTTAGATCTATTTTCTTGATAATTCATTGGTGTGTTAATGACATAAATTACTGTGATG TACAGTAATGCATCACTGCCCTCAAGGTCTATTGAGGTTGGATAAGACTACATTTTCTCA TCCCCACCCTCCTGAGATTCCTACTTTACTAAATAGGCTAAGGCTTCTGCACTGGTGCCT TTAAAAAAAAAAGTTTTTTTTTTAGAGTGGTTTAAGGTTCACAGAAAAAACTGAGTGGAA GATGTAGAGAATTCCCAAATACCCCTATCCCAACATACACGCACAACCTTTCTCACTTCA GTATCCTCAAAAGTGGCATATTTGTTACAACTGATGGACCCACATTGACACATCATTATC ACCCAAAGTCCATTAATTTACATGAAGGTTCACTCTTGGTGTTGTACATTCCATTGGTTT TGACAAATGCATGATTACAGGTGTTGACCCTTATGATATCTTACAGAAAGAGTTATACTG CCCTAAAAAACCTCTGTACCCTGACTATTCATCCCTCTGTTTCCCCTAATCACTGGCAAC CACTAGTCTTTTTACTGCCTCCATGGTTTTGTCTTTTCTAGAATTTCATAGAATAGATAT CATACAATATGTAGCTTCTAAAGATTGATTTCTTTCACTTAGTAGTAGCAATTAAGGTTT GTCTATGTCTTTTCATAGCTTGATAGCTCCTTTCATTTTGGCACTGAATTAACATTCCAT TATTTGGATGTTCTACAGTTTATTCACCTACTGAAGGACATCTTGGTTGCATCTAAGTTT TGGCAATTATGAGTAAGGTTGTTGTAAGCATGCCTGTGCAGGTTTTCATGTGGCAATAAG TTTTAAATTCCTTTGAGTCAGTTCCAAGGTGTGTGATCACTGAGGTGCATGATAAGACAT GTTCAGTTTTGTAAGAAACTGCCAAATTGTCTTCCACAGTGGTTGTGCAGTTTGCATTCT CACCAGCAATGAATGAGAGTTCCTGTTGCCCCACATCCTCACCAGAATCTGATGTTGTCA GTGTTTTGGATTTGACCATTCTAATAGACCTGTGGTGGTATTTCACTGTTCTTTCAATTT GCAATTCCCTAATGGCATATGATGTCGAACTTATATGCTTACTGGCCATCCATATACCTT CTTTGGTGAGGTAGCTGTGCAGGTCTTTTACCCATTTTTTAATTTAGTTGTTCATTGTCT TATTGCTGAGTTTTATAAGTTCTTTGTATATTTGGATAAGTACTTTACAAGATGTGTCTT TTGCAAATATTTTTCTCCCAGTGTACCGCTTGTCTCCTCATTCATCGTTATTAAATTTTA ATGAAGTCCAGCTTATAATTATTTCTTTTATGGATCATGCCTTTGGTGTTGCATCTAAAA AGTCATCATCATTCCAAGGTCATCTAGGTTTTCTCCTATGTCATCTTCTAGGAGTTTTAT TGCTTTACACTTAGGTTTATGATTCATTTTGAGTTAATTTTGAGAAGTGTATAAGGTCTG TGTTTAGATTCATTTTTTTTTGTATGTGAATGTCCAACTGTTGCAGCACCATTTATTAAA AAGACAATCTTTGCTCCATCGTATCGCCTTTTCTTCTTTGTGAAACATCAGTTGACTGTA TTTATGTTGGTCTATTTCTGGGCTCTCTATTCTGTTCCATTGATCTCTTTGTCCATTCTT TTGTCCATTCTTTTTGTAGTATGGACAGTGTCCATACTACACTGTCTTGATAACTGCAGC TTTGTAGTAAATCTTGAAATTGGGTAGTGTCAGTCCTCTGACTTTGTTCTCTATTCTCCT TCAATATTGAGTTGGCTATTCTGGATCTTGTTCTTCTCCATATAAACCTTAGGATCAATT TGTTGATAGCCACAAAATAATTTACTGGGATTTTGATTGGGATTGCATTGAGTCTACAGT TGGGAACAACTGACATCTTGACATATTCAGTCTCCTTATTCATGAAAAAGAAATATCTCT CCATTTGTTTAGTTCTTTGATTTTGTTCATCAGAGTTTTGTAGTTTTTCTCACATAAATC TTGTACACACTTTTTAGATTCATACCTAAGTATTACATTTGTTGGAGAGTATTAATGTAA AACGTAAATGATAATGTGTTTTGAATTTCAAGTTCCACTTATACATTGCTGTTACATATG AAAGTGATTAACTTTTGTATTGCCTCTGATTCTATCTTCTGGAAGAGATTGTGGAGAATT GACATAATTTCTTTTTTAAATGTTTGATAGGATTTACCAGTGAATCTATCTGGGCCTGGT GCTTTCTGTGTTAAAGGTTATTAATTAATGATTCAATTTCTTCAATAGTTATAGGCCTAT TCAGATTATCTACTTTTTGTATGAGTTTTGGTAGCTTACATCTTTCAAGGAATTGTTTTA TTTCATCTAGGTTATCAAGTATATGAGCATAGAGTTGTTCTTAATATTCCTTCATTATCC ATTTAATGTACATGAGCTCTATAGTGAGATCTTTTTATTTTGATATTAGTAACTTGGATC TTCTCTTTTTTTTCTTAGTTAGCCTGGCCAGAGGCTTATTAATTTCATTGATCTTTTTAA GGACCCAAATTTCAGTTATGTTGATTTTCTCTATTGATTGTCTGTTTTCAATGAAATTGA TTTTTGCTCCAAATTTTATTTTTCTTCAGCTTACTTTGAATTTAATTTGCCTTTTTTTTT CTAGTTTTCTAAAGTGGGAGCCCAGATTGCTGATTTTATTTGTATTTTATTTTTATTATT TATTTATTTATTTATTTATTTGAAATGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAA TGGCGCAATCTTGGCTCACTGCAACCTCCACTTCCTGGGTTCAAGTGATTCTCCTGCTTC AGCCTCCTGAGTAGCTGGGATTACAGGTGTGTGCCACCATGCCTGGCTAATTTTTGTATT TTTAGTAGAAACAGGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCGTG ATCCGCCCGCCTCATCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGTCGTGCCTGGT GGATTATTGATTTTTAATCTTCCTTTCTAATATATGCATTCAATACTATAAATTTCCCTC TAAGCATTGTTTTCACTGCATCTTGCAAATTTTGATAAGCTGTATTTTCAATTTCATTTA ATTCAAAATATTTTAAAATTTCCCTTGAGATTTTCTTTTTGACCATGTGTTCTTTTGAAT TGTGTTGTTTAATCTTCAAGCATTTGGGGGTTTTCCAGCTATCTTTCTGTTATCGATATC TAGTTTAATTTCATTTTGGTTTGAAAGCAGACATTGTATGATCTCTATTCATGCAATTTA AATTTGTAAATGTGTGTTTCATAGCACAGAATGTGGTCCATCTAGGTGAATGCTCCACGT GAGCTTGAGAAAAATGTCTTTTCTGCTGTTGTTGGCTAAAGTAGTCTATAAATGTCAATT ATATCCAATTAATTGATGGTGCCGTTGAGTCCAACTATGTCCTTACTGATTTTTGGCCTG GTGCTGTCCATTTCTGATATAAGGGTGTTGAAGTCTTCACATATAATAATGGATTCATCT ATTTGTCTCTGCAGTTCCACCAGATTTGCCTCATGTATTTTGAAGCTCTGTTGTTAGGTG CACACACATTAAGGACTGTTATATCTTCTTGGAGTATTGATTCCTTTATTATTTTTAATG CCCCTCTTTTTCTCTGATAACTGTTTGCTCTGTCCAAAATTAATATGCTACTTCCACTTT CTTTCGATTAGTATATCATGGTCCACCTTTCTTTATCTACTTAGTTTTAATCTATCTGTG TCTTTTCATTTAAAGTAGGTTTCTTGTAGACAACATATAGTTGGGTCTTGTTATTTTCAT CTACTCTAACAATCTCTGTCTTTTAAATGGTGTATTTAGATCACTGACATTTAAGGTAAT CATTGATATAGTTGGATTAGTATCTACCATATTTGTTATTGTTTTCTATTTGTCGTCCTT ATTCTTTGTTTCTAGTTTTGTCTTTCACTCATTTTCTGACTTTTGTGGTTTGAACTGAGC ATTATATATAATTTCATCTCCTTTCCTTTCATAAAGTATCAATTATACTTCCTTTTTTCT TTTTTTTTTTTTCTGGTAGTTGCCCTAGAGTTTGCAGTATACATTTTTAACTAATCCAAG TCCACTTTTAAATAACACTACACCGCTTTACAGGTAGTGATTGTATCTTATAATAACAAA ATATTTCTAATTTTTCCCTCTTGTTTATTTTATCATTGTTGTCATTCATTTTACTTATAC ACAAGCACATATATATATACATATGCACACATAAACAAATGCATGGTTGCTATGATTGTC TTGAACAAATTGCTATCTGTTAGACCAATTAAGATTAAGAAAAATAAAAATTTTTATTTT ACCTTTACTTGTTCATTCTCTCATGCTCTTCCTTTATGTAGATCTGAGTTTCTGGCCTAC ATCATTTTCCTTCTCTTTAAAGAACTTCTTTTAATATTTCTTACAAGATGGGTCTACTGG CAACAAATTATCTCAAGTTTTGTTTGAGAAAATATTTCTCACTCGCTTTTGAAGGATACT TACGGAGGTTACAGAATTTTAGGTGCTTTGGTTTTTTCTTTCAATACTTTAAGTATTTCT CTCCATGCCTCTTGCTTGCATGGTTTCTGGGAAAAGTCAGATATAATTTTATATTTGCTC TTCTATAGGTGAGGGGTGTTTTCCTTTGGCTTCTTTCAAGTCATTTTTCTTTACCTTTGA TTTTTTGAAGTTTGAATATCACATGCCTTGGTATAGTTTTTGTTTGGTTTTGGGTTTTGG TACTTATCCTGGTTTGTGTTCTCTGAATTTCCTGACTCTGTGGTTTAAAATCTGACATTA ATTTTGGGAAATTCTCAGTCATTTTTGTTTCAAATATTGCTTCTTTTCCTTTCTCTTTTT CTTCTTTTACTGCTGATATTCTCGTTACACATATGTTACATCTTTTGTAGTTATCACACA GTTCTTATTTGTTTCTGTTTGTTTTCATTCACTTCCTTTTCTCTGTTTTTTGGTTTTGAA AGTTTGCATTGTCATATCCTCAAGCTCAGAGATTCTTTTCTCAGCCATGTCCAGTCTACT AATGAGCCCACCGAAGGTAGTCTTCAATTTGTTATAAGCGTTTTCAATCTCTAGCATTTC TTTTTAATTCTTAGAATTTCCGTTCTCTGCTTACATTATCCATCTGTTTTTGTATGTTAT CTATTTTTTCCATTAAATCTCTTAGCATACTAATCATAGCTTTATAAAATTCCTCATTTG TTAATTCCAATATTCCTGTCCTATTTGACTCTGGTTCTGCTGTTTGTTCAGTCTCTTCAA ATTGTGTTTGCCTTTGACTATGCCTTATAATTTTTGGTTGAAAGGTGGACATGATGTACT GGCTGAAAAGACCTCATATAAATAGGCCTTTAGTTAATGTATTGGTAAGATATGAAGGAG AAGTATCCTATAGTCCTAGGATTAGTCTCAGTTTTTTGGTGAGCTTGTGCCGCTCACCTG TGAACTTCACAAGCGCTTCTCAGGGTTTTTTTTCTCCGTTTGGTGGGACAGGATGGCTGG AGGGGGCTGGGCTTGTGTATTTCCCTTCCCACAGGTGAAAGACTAAAGGTCCTGGGGTTG CGTATTTCCCCTCCCCAAGGTAGGCGAGGATCTAATATAACCTCAGAAGTTTAGGCTGCG GTAAAATAATTTCTTCTGAGGACAGGCCTTTTTAAGAAGAACAGAATGCTCTGGCATATT CCAAAATGGTTCATTTTTCCCACTCCCTACCAGAAACACAAGGAGATTTTTCTCCAACAT TTACTGTGAGGACCTGGTGGAGATCCTGGAGGTAAAACTCACAAAGGTGTAGAGCACCCG CTCCATGACTGCATCCCCCTGGAGTTTATATCCATGTATAAACTCCAGCAATTCATCAGT TAGTCCTTACATCTTCCTATCCTGGCAAAGGTTCCTGCAGAGGTTTCTGCTCTGATATGC CGTGTCTGCCTGTCTGTCTCTCCAATTTTTTGGACAATGAGTTGTCCTGTGACCTCATTC CTCTGATGGATCTAAAAACAACTGTTGATTCTTCAGTTTGTTCAGCCTTTTTCTTCTTGT TTAGATGAAATAAAGACTCCTAAGCTGCTTACATGCCAGACCAGAAACTGGAAGTCTTGC TTGTACCTGTTTAATGGTTCCTCCATTTCTTTCCTTGTCACCAGATAGCTGTGGTCACTT CTCGCCGTGAGCAGTGTGCCCACCTCTAGTTGACCCTCCACACGCTTTCTAGTGTGTGCT GTGGACAGGAAAGCTAGTAACCGAGTTTGTTAGAGCTGTGTGTAAAATAAAAGTAAAAAG GCTCTGAAGAAACATCTCGGAGACCTCCGATGAGTAACATGCATTAGCTTCTGAGCACCT TTTGTGTGTCAGGCATTTTGGCTGCTCAGAGCTCTCAGTCTTGCTCTGCTCTGCACTGCA GGGTAGCTGAATTGAGGGAGGTAAGTTCTGCATGGTGAAATCAAGAGCGATTTCAACTTC CAGGAGGGAAGGCAACTGCTATACTCAAAAATCCTTCTCTTTTGAAAAATTAAGAGGACT GATTACATTATATCACTTTGAGCAGGTTCTTATGAAGTAAATAGAGGCAAGATTAACAAT CTCTGGGTCTCAGGAAACAGTGAGTAACTTGGGAAGATTATATAGAGGCTACTGGAAGAA ATATACCAGCTTCATAATTTATAGTTCCCATTTATTGAATAACAGAAATGTGCCAGGCAT TGTTCTAAAAGCTTTTCAAGAAGTACTTAATTTTTATAAACACAGTAAGGTAGATATTCT AATGAAATCACCTAATAAAATCACCATTTTATTAGGTTGGTGCAAAAATAATTACAGTTT TTCCCATACTTTTAATGGCAAAACCACAGTTACTTTTGCACCAACCTAATAGAAACAAGG AGACTTGCCCAAGGTCGTGCATCAATTAAGTGCCTCAAATTGAACCCAGGTCTGCAGAAT CTGAATTTGTGCTTTTAGGCATTTTCATTTAATTCCACACTTGTTAATTCTTCATCAGCA GCAGCATTAATCAGAGTGTGGTGTTTTCCATCCTTATAAGGTCCTGTCTCCTTGTTTACC CACCCCTTCTTGGATTATACGATTATACAGACACAGCACTCTTTTTCATGATGCTCCAAC CCTAAAGGTGAGTGGAAAGCACAGGAGTCTGTAACTCCCCTGGACCCAGAATCAAACTGA AATGAGATGGTTTGATTTGGAGTCAGGATTAACGTGGCCCAATTGAGAAGTCAAGTAAAA CCTGGGGGGAGATTAAGCCAAGAAAGGAGATGCCAGCTCTCTGCCTTCCTTGCCAGATGG CAGGTGTGTGTATGTGTTTATATAATCAATGCCCACACATCCGGCTGTGACTTCTCACTC AGAGTTATATGAACATTGCAGGGGTTCACAAACTGTCTGGAGATCTAATTACCAGTTTCA TAAGCCCAACAGAGTGCCAGCCACAGAAAGCAGCCAGGAGAGGGAAGGAGGAGGGGTGCA AGTGCTGAGCAAGGCCACGTTGTTATTAAATGCTACATTCAGCACCTGTGCCATGGGCTG AGCCTGCCAGTCTCCAAGGGAAAGCTGCCAAGCCCAAAGGCACTGCCAAGCTCAAAGGCA CTCTCAGGCGGTGAGCCTCTTCCAGGAAGCCGGTCTCCAGACCATCACTGGCAGAAAGTC CCATGCTATTCATAAGAACCCTTCCCTGAATAAGAATGGCAGACTCTACTCCCCATGCCA GATGTCCCCAGAGGGAAGACTCACTAACTGGTCATCTTATCATCATTGTTTGTAGACCAG AGGCCCTTGGTCTCCCTCCCCACAGTGATTTCTGAGTGTTGCCATTTTAGAAGCAGAGAC ACTGATGTTCTGGGGTCCCCACTTACCCTGGCAAAGGTCCGGAAGCCCTGGAGGATGGGT CTGTAGCCTGTGCAGCGGCACAGATTTCCTGTGGGCCAAGGAAAAAACTGCAATGTCAGT GCAGGGCCCTGGGATGGGTGAGGAGTTTGTGACTTTGCTTGCAACTAAGTTGGGTGCTCT CTTTACCAGGCTGCATATTCTGTTACCTCTGTCTGGAAGGCCTCTTGGCCTTCTCATATC CTGACTTCAGAAAAGTTATCATGATTTCAGGAAGTCTTTCCTAGAATGGAAGCCTTCCTA GAATGCCCAGACTGAGTCAGGTACCTCTCCTAAGTGCTCCCACAGTGGCTGATCACAGCT TCATCAGTTAGCCTATCAGACTACATTACAAACTCTCCTCTTCAGAGTATGAACTTTTTG AGAGTAGAGGGTGTGTCTTTTATCCCTGTGGCATAGGATGTGACTAAAATAACTGAATAA ATGATGGAAATGGTGAATAGATGGGGAGGCTTCTCTATTCAATTCAGAGAAGCAGACACA TTGGTGGTCTTGGCCCTGCAGAATCCTGTTCTGGTGAAAACTGAGAGGGAAGGAAATCAT ATCACTAGCCCCCGTGGAGTTTTCTAAATGACGTCTTCCTGCACCAGCCATGCACTGCCA ACCCCACTCCAATACTGGTGGAAGGCAGACAGACACCTCAGAAATATGGACACAAAGGCA GGAGACCCCAGGAGGTCTCCACACCAACCAGGAGTTCTCCCAAGTAAGAGAGGGTTGGCT TTCTAGCAGATCTTAGTCACCACCTTGTTGGGGGGCCTGAGCCCTTCCTCCAAAGGGTAG TCCCTCATGCTTCTCACCCTGGCACTTGCCCTGACCTCTGCAGGGCCTCGTTTGCCATTC CACCTCCTAGGCTGTGCCTGAAGGCCCATACCTTGGAAGGCATTCTCAATCTCCTCCATG GTGGGCTCGGGCTGATTCCGGAGCAGTGTGTACATACTCATGACGATGCCAGGGGTGCAG AACCCGCACTGGGAGCCGTGGCTTTTGGCAATTCTCTCCTAAAAGATACAGATGACATAG ACACCTGGGATGGCAGAACCCTCCCAGGCTCCCCAAAGGACTCGACTGGAGCCAGCACAT GTTGAGAGATAGTGGGGGTAGTAATCACTGCACAGAGTCAAGCCCCAGTGCCACCATTTA CCAACTGTGACCTTGGCCAGTTTCCAAGCCCTCTGAGTCTAGGTTCTTCATCTGTATGAT GAGGACCATCCTTGTAGTTACCTCTAGAGCTGCGATGAGGATTAACTGAGATATTCATGT AAAACCCTTAACACTGTACCTGCATATAGCAGGCAGTCAGCCAGTGTTAGCTATGACTAG GAAGGTCCCTTCAAAGAACAGTGACTATCATAACCAGAAGGCAGCTTCTGAATGGATTGG GTGTGGCATATGACAGAAACAGTCAAAGGTGATGTCTAGATTTTTGTCTTGAGCAATTGG GTGGATGGCTTTGCCATTGACTCAGATGGGAGAAGACTGGGGAAGGAAGCCATTAGGAAA AGAGTAGGGTTTTCTTAAGTTTGAGATTAGACATCCGTATTGAGATGTCAAATAGGCAAT TGGAAATGTAACTTCTGAGGGGAGGTCAAAGCTGAAGTTGTAAATGAGAGTATAGGGATG AAGAAGGGGAGGGGCCCAGGTCAGGGCTCAGGGCACTGCAGCAATTAGAGACTGAGCAGA GGAGGAGCAAGTGTGGGGAGAGAAGGAAAAGCCAGAACCACAGTGTCACAGAAACCAAGA GAAAACAAATAAATGGACAAGAAGTGGAATCTGGCTCTGAAGCCTATTTGTAGCCAAAAT AAGTTGATTAGGAATAAGAACCTGTACCATTGGATAGGGAGGATTTTAGGTTGATTATAC AGATACAACCTAATTTGGTTTGGCTGTGTCCTCACCCCAATCTCATCTTGAATTGTAGCC CCCATAATTCCCATGTGTTGCGAGAGGGACCCTGTGGGAGATAACTGAATCATGGGGGTG GTTCCCCCATCCTGTTCTCATGGTAGTGAATAAATCTGACGAAATCTGAAGGGTTTCTGT TTTCACTTAGCTCTCATTTCTCTTGTCTGCCACCATGTAAGATGTGCTTTTCACCTTCTG CCATGATTGTGAGGCCTCCCCAGCCATGTGGAACTGAATCCATTAAACTTCTCTTTCTTT GTAAATTACCCAGTCTTGGTTATGTCTTTATCAGCAGTGTGAGAATAGACTAATACTTGA CTCCTATGTTTAAACTGTTTATTCTTTCTTTCATCTGTTTGTTTCAAAGAAAATAACAAG CCTTAATTAACCCTCTCACGTCTCCTTCAGGTTGGACAAGTTTAGTAATTTCCCCTCTTC CTGCCTAAGAAACAAATCTATAGATGGGAAGCAATCCCACCCCGACCTGGCTGGCCTCAC ATGACTGGCCCAAGATGCCACTCCAAGGAATAGTACCAGCCTCTCCGCAGGAGGCTCCAG CTCCATCGCCTGAATGACATGTCTCCTCAAATAATCAAGGGAGGATTAAGACCTGGGCCA AGCTCTGGTAACTTCTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCGCCC AGGCTGGAGTCCAGTGGCACGATCTCGGCTCACTGCAAGCTCCATCTCCCAGGTTCACGC CATTCTCCTGCCTCAGCCTCCTGAGTATCTGGGACTACAGGCGCCCGCCACTCCGCCTGG CTAATTTTTTGGTATTTTTAGTAGAGATGGGGTTTCACCATGTTAGCCAGGATAGTCTCG ATCTCCCAAAGACCCCAAGTTTCCTCAAACAAAATGCTTTGGGGACAATGGCCGTTCCTT CCAACAGGGCTCTACTCCCCTTTCTTTCCACTCAGCCTAACAGCATCCTGATTGTCTCCC CAAACCAGTCTAAGATTATTACTGCCCATTTGCCCCAGAAATGTTTCGGATTTCAATGCA TTTTCAGGTGGTCTGATACCATCAAGGAGAAAGCCTTGCTCAGGCACTAAATCTCTGTCA TCTTATTTAGCACTTGCTAACCTCCAGTCTAATGAAAGAGGAGGCCTAGCAGTTTACATT TGTACTATCTGCGGGTGGGAGGTAAGGGGTGCAGAATTACCATTGCAGGGAGTAAGTGGG CTTATAAACAAGGGGCACAGATAATTAAAATTCAAATCTGGGAAGGCTGGGAGTTTCCTA AACACACTCCAGAACAAAGTGAGGAAGCTCTTCTGCATCCCTTCCTCCAAGTTCTGGACT GGTCTAGCCACCAGATTCAGTTGGCCTCTTGGGTCCCTTCAGATCATGCAATGTTATAAC CAACCAGCTCACAGGAAGGAGCTTCAGGCTTGGGTGTTTCTTCTTTTCACCTCACGGTAC CCAGAGGAGATGGGGAGGTGGCCAGGGTGAAATGCCTTCTTAGATTAAGCAGTGAAACTC TTCCCAACAACCCAAAGCAAGTCTGCAACTTTGGCATGAGCCTCCCTGCAGAGGAAAGAG CCTGATCTCAAGAGCACAGCTCCCTTTCCTCTGTTTACCTGCACAGGATGCAGCCTCGTC TTGGTGCTTCCTATTCCTTCCACAGTTGTCACTGCAACATGGTGCAAGGAGCAGATGGGG GCCAGGCAGGCATTGGCAGAAAAGTGGCTAGAACCCCAGATTAAGGTCATTCCATTTATT GTCCACTCAGATCATCAGAATGGGCCTGACTGTGAGCTCTGGAGGACTTTGTGAGGCTTT ATGTTACGTCTCTCCGCTCCCATTTATGTTCTTGTCTCTTCTACCAGTGTCCTCACCTCT CCACTGAAGACTCTGGGAAAGGAACAAAGGAAGCTCTCCTTATAGGTAAAGCTGAGCCCC TCCAGAGTACTGTGGGATCAGGCATCAGAGCATCCTCAGCCTCTGAGCAGGAGCAACGGA GCCAGGGTCACTTTCAGTCACCTCTTACTCAGCCTGACCCAGGAGGCTGAGTCAAGAGGA AATTTCTCTGGCAGGCTGCAGCCTTAAAGCATGCTCCTGCCTGCAGGGCTGTTCCTTAGC TTCCAATCACTTTGCTTCCCTGCATTTCCTCGCCTCTATTGCTTTCATTTCTCTGTGGGG AAAGGGGGAGGAAACCCCCAGGCAACATGAGACAGCAAGCCCTTAGCTAGAACTTCCTTG CATTCTTCTGTTATTCATCACTCATTCACTTACATTCAGCATCAGTTATTGAGTGCCAGA CATAAGTCAGGCACTCTGCTGAGGGCTGGGAAAATAAAGATGAATAAGATGAAAGCTCTG CCCTTCAACAGACTGCAGTCAACTGAGAAAACCAAAGTCCATATGAAGGTGCAATTTAAA TCTTGTTAAAGTAAATTAAAAAGGAGACCAGGCCTGAAGACTCAGCAGAGGAAACCAGTT AGGCCTCACAAGTGACCTAAACTGTGCTTGATTTGCAGCAGAGTCTTAACTTGAGCTACT TCTTACGAATATCTTTATATTAAAAAAAAGCCTTACGATCAACCAATCAGAAGTAGTCAA CAAACTTATAACTATAGTACTAGGGACTTTCCAGTGGGATAGACCAAGTAAGGCAATTGT ATAATTGTAACCAATCAAATAATTTCTTTGCTTTTTGCCTGTGTCCATCCTACAAAAACC TCCTGCTTGCATTTCCCTGGTGGAGCTCCTGAACTGCTTCTAATGTGGAGCTGCTTGAGC TCATGAACTGTTGTTTTCTCAAATAAACTGTAAAAATTGTATCATGCCTGAGTTTACATT GGGAATGCTGTGCACAGGGCACTATGGGACCAGCACAGTCAAGGGGCACCTAACCCAGTC TTGAGAGATCCAGGATGGCTTCCTGGAGGGGGTGATATTTTTGCCCAGTTGTAAAGAGCT AGTAAGAGTTAGTCAGATAGAGAAATCCTAGGAGAACTTCCCAGCTTAAACAAAGACCAA GCAATTAGTGGGCCTGTGTCATTGGTATTTCACAATTATCTCTGCTTGAATGGAGTGCTG GGCCCATGGTGAGAAAGAAAACTGGAGAAGAAACCTGGGGCATACTGTGCAGGGCCTTGC CCGCTAAGCAAAGAGATTTTGTCCTGGGGGCAATGAAGAGCTATTGAAGGGCTTTATGGA ATGTGATATAAATGTGGATTTTAGAAAAGTCATTTTATCAGCAGTTCGGAGCCTGGTCAA TATTATAAGCCTAGAAGATACTTGCTAAGAGATCATTCTACAGTTTTCCTGTGCACAGAT TCTCCATAAAAACAGGGGCTCACACATGCGCACATGCACATACACACATACACTCATGCA CTCCCTCACAAGCTGGTCCTGCATCGCAGCCCCCATGTGGGTGGTCAGCCAGCAGGCAAA GGATACACGATCTTGTTCTGCAGACGATCATACTTGGAGAGCATCACTGTGCAAGCCCCG CAGCCCCCCTCTCCACAGCCGAGCTTGGTTCCACTCAGCCCCACTGGGTGGTCAAGAGTT AAGGAGAATGAACTCAGGGAGAGGAGTCTGCTGGGTTGCTAGGAAATGCCTGGGCAGAGC TGTGGGCAGAGCCATTCATTCCCACACGTGCTCAGGCCCCTCAACCAAGGAAGGCAGCAG GCCCACTGGCCTCCTTATTCAGAGGGGCTGCACTGCACCCTAGGGAGGCAGGGAACACGG CCATCTCCACTGCACAGAAGAGCAAAGGCATCAGAACCCCATGGACAGCACCCAAGTAGC ATCTCTTGGGACATGAGTTCTAGGACTGGTCAGTCCTAGAGCCTTCTCTTGGGTTGAGGT CTTCTATGTGTGAGCAGGTAAATCATACACCTGAGCATACGGGGCAGTTCTCACATCACT CCCAGCTGGGCACACCATGAAGCCACTTGGGCCAGAATGAGACATTGATCTGTTCTGGGA CCTCTGAGTCCTTGCTTTTCACTCTGAACTTTTTGGGCTGATAAGTCCCCAAGAATCAAA ATTAGGGCTAGACCAGAGGCTTTTGAATATTTGGTCCAAAAGATATGTGAATGGAAATTA AAATAGAGTGGTTTTTTTAGGTCTGGGTCCAATATTGGGCCTCACTCTTACATATACTTG CAGAAAGACCATCTGCTACTTTGAGTTTTAAAAGTGCCTAACTGGTAAGCTATTCTAGAG AACAGCTATTGTGGAGGTCACTTTCCCTGAGTCACATGGCTGCTTCTCCCTCAGACCTGC AGGCCTCTAAGCCACCCACTACCTACTGAAGATGGAGGGAACTGAGGATATAATCGCCTG GTCACTTCTCTCATTTTCAAGACAAAATTTAAAAACAATGATATAACATCTTATTTTTGA AAAGCACTTTCACCTAGATACCTGTTTGACCTCCAGAATGATTTGGTTAGCAGGTAGGAA AGAAACTTCCTCACAGATTTAAAAAAAACAACAAACTGAGACCCAAGAGGTAACGTGGGC CACACAAGATGACACAGGAACACGTTACCCTGCCGGTGTGGCCCCATCACAGCCATCGGA CTCCAGACTGGGTGAGCTCCCTTCATCACGCTCCTTCCTCCCCAGCACACCTGGGAAGGT TTTCTGTGTCCTAGTCAGGATATATGCAGCTCTCAGCAGGTCAAACAACTTTGGGGGCAC CTGAAGACGAATGGTGGCACCTGAAGATGAATGGTGGCAGTACAAAGTCTAGCAAGGTCT TCTTCCAGCCTGGAGACCTTTCTGGAAGCTAGTGTAAAAGTCAAGGCTGGAGTTTTCTCC CCCATCTGGAACTCCCATAAATTGACTCTCAGCACAGATAGCCATAAGCTGCAAGGTCAT CCTACTTATGTGCCAACTTTCAGTTTTGCATTTCATTTAAGATGTGACACAGCCAATTGC TGATAAGGAATTTCTGAGGCTTCTGGGCCTTCAAAACTACAATGGAAATGATTAAAAAAT TAAAATTTGTTTTATTATTAGAAAGCTAAAATTGATCTCAATAATCTCTGAGAATGAGCT TCTCTTCCCAGACCTCCCAGGTAGATGGGCTGTAAATGGAGTTCCATGCAATCACCTGAT CCGATCTAGTGACACTTTCACTCCCCAGCACCACCAGGTTTATCTTCTGTGAACCTCCAG ATACACCCACTTAAGGTAAAAAATCCAGAACAAAGTACACCAAAGCCAACCACTGTACTG TCTGATAGGAGGGGAGCAAACCAGAGTGAAAGCATGGGCTCCAGTCTCACTTCTGTGCGT GTTATAATAATCTTTGCTGTCCCCAAATATGTCACTGGAAAGACCCACTAGACACCCCCG CTAGGAGAAGGAGGGTTTTGTTGACAGAGGTCAGGATGAGCACAGTCCTGCTCACAGGCC CCCTGGAGAGTTGCCAGTGCGGGTGAGAGGTTGGGAACACAGCTCTAGGCTTTGGTGCAA TCTCCATCACTATTTCCCCAGAACACACTAGCAAAAGGCAGGTCACTTCACATATCAAGG CCTCAGTTCCTCCTCTGTGAAAAGGGAGTGTTACGCTTCCATGGGATTCCTGTGGAGATT GAGGTGAGCTGCACAAATCACTTTGAATCCTGCCTGTATATAGGAAGTGCTCATTAAATA TTAACTCCAATTATTATTATCGTTTTAGTTCCAGGGTCCCAGAATACTTCCGATACTCAG AACTAAAGGTAAAGGGGCTTTTCCAGAAGCCCCACCCACACTGAGTGAAGAGCAGCACCC CAGTCTTTCTAAGGAGTCCCCCCACCCTCCAGGGCTCCCTGTTTGCTGTTTCTACAATGA ATGCTACCTGTATAGGATTCTTACCTCACGCATCCTTTTCCCAATAGACACATGTTCCCT TGCTTCCCTCCACCTAGGCAGAGCTGGAAACATTCCCCAGGAACTCCATTTATGTATTAA GCAAATGTCACCTAAGGAAGGCCCCCCTCTTCCCACAGAGGAATGACCATGAAGCTCACC AAGGCTAATGAGGACCTTTCTACAGGCCCTGGATTAAACCTTGGCATTACTAGAGTCTTA GCGGGGAGACACCTCGAAGATCACCACAAACAATCCTCTCATTCAGTAGCTGAGAATTTC AGATTACAGGTGCAACTAAAATGCAAGTGTCCCAAGTCCTAATCCAGTGCTCTTTCCTCC ACACCTCAAGGCCACCCCACCAGTCACTAGGAAACAATGTAAGGCCTACAGAATCAGTCA CCATTGCCCCCCTTCTCCGTCACTCCCACTCCAAAGTCAGGATACACTTTCTTCTCAGGT AGGCCAAAAGGGTTGTCTCTGGATCTGCATTTTTCTCCACCACCTATTAAAATAAATGAA AGAAAAATATATCATAGGTATACTTAGTCATCTTTCTGCAATTAATTTCTTCCTTCAGTG TCTCACTCAATAATTTGTAGAGTTAGTAGGAAGTGTGATATAGTTTGCACTCTGCCCCTC TAAATCTCATGTTTAATTGTAATCCCCAGTGTTGAAGGTGGGGCCTAGTGGGAAGCAATA TGATCATGGGGGCAGATTTCTCATGAATGGCTTAGTGCCATCCCCTTAGTTGTGAATTAG TTGTCACGAGATATTTAAAAGTATGTGGCATCACCCCCTTCTCTCTCTCTCTTGCTCTTA CTGGCCATGTGATGTGCCTGCTCCCACTTTGCCTTCTGCCATGAGTAAAAACTCCTGGAG GCCTCCCCAGAAGCCAAGCACATGCTGGTGTCATGCTTGTACAGCCTGCAGAACTGTGAG CCAACTAAATCTCTTTTCTTATAATTACCCAGCCTCAGGTGTTTCTTTATAGCAATGCAT GAATGGCCTAATACAATGTGCTAAATAGATCATGAAAACTAAGGTATTTTTATGGCAACT CCATAAGAATGAACCTATAAACTACAGCCAGACAATGTATATACTCAAATCCTTAAATTC TAAAATTGTACCTCAATGCTCACCTTGGGACCCACCACAGAACATGCAGGCATTGCACCT TCCACGCTGGCTCGACCAAGGCCAAATCCCCTTCAAATAAAACCTGTCATCTCATTTCAA CTGCTAGATCACACCTGTGAATTTCAGGGGCATCTGAGAGCATGGCATGCAGATCTCGGA CTTTGCCTCTTTGAGTATACAATCTCAGATCCTGCATGTGACTGTGGAAGGCCATTCTGT TGGCCTGTGCTCAGAGCAGAGTGTTGGCATGTGATGCGTATTAGTCAACACTAATACATG TCAGAAATGAAAGAGAAATCTCAAACCAAAGATCCATCACTAGGTTCAATAAGGTGGAAA AAGTGGTCTAGAAAGTGCGATGTCAGTTCCCACTGTGAATTGTCAAAGGAAATCTACAAA AACCGATTTCAGTACTCTTCACACATTACCAAAGCTTAAAAGGGTGTATATTATTGGGAT AATAAAGAGAAAGAATTCATGATAAGGTTTTCGTTGGAGGGAACTATACTACCCACACCT TCCTAAAGGAGAAGGGGAGGAATATTTGCCTCCCACCTCAAACTTAGTGAGGGAGCTTGC TTTGTGCTACATAAAAATCTAACATGCCACCTTTGCAGCATAGGGGAAGAGATAGGCTTA ACAAGAAATTAATACCGACAATGACAAGTTTAAACTCCTCATTAAACTTAAGTTGGAGAG GTGGCTGTGCTGGGGTTGGTATACACTCCCGGAGCTTGGTAGAGCAGAGGATGTGGAAGT GTCGCCTATGGATGTAATGCAAGCCATTCATGAGATAAAAAGAGCTGGCTTGGAGGTCTT TAAATCATTTCCCAAAATACAGGATAGAGCATTCAATAAAGAGAGACTGTGTGGAGTGGA CTTCCCCAAACTGGAGGCTGATGGAGAACAGCAGCCTGAGAAAAGTGCATCACTCATATC ATGAGACATGCATGCAAATATTCCCTGTGGTGGCCCTTGAAGATCCTTGAAAGCCATCAC AAGAAGAATGAAAGGTCAGCTCCAAACACCTAAAAGGCTCAGAAAGCCGGAAGCCATCTT ACAATAGTACCAATTAAAGGAGAGCTTTCTTGCTATCCTCACCCCGCCGTCCTGAATTGA GACTGTTTGGCAACTTAAAAATAACCATAAGATTTTTTATTGACTAAGAGTAATAAAAAG TTCATGAAACTGCCAGAATTTGTCCTTTGAATAAAGTTTAAAGGAAAGTAGATGAAATTA ATTTTCTTATGTGATTACACCCCATGAGTCCAGCTTATTCAATATCCTGGTTACAAATCA TAGAAGTAATCATAAATGCACAAAATAGCAATCTTTATCACCTTTCTTGTAGACAACATT AAGAGCCTCTTAGCTTACCACCACATTGTTCATTTCTCCCGTACTGCAGTTCTGCTTTTA TCACATCACATCAGTTCCCTGCTCAGTGCTTTTCATGACCACCCACATATTCAAGGTAAC ATCCAAGTTCCTTAGGCTGTCTTTCAAGGCCCTTTTCAATATATTCCCAATCTTCATTTT CAGCCTTTCTCCCTTCTACTTCCCTGCCAAGCTGGTCATCTTAGTGCACTAAAAATACAT TTTATATCTTCTAATTCCTGTGCCTTTGACTATGCCATTCCTCTTCCACCTGCATTTTGA CTTATCAGAAGACTTCAAACAATTTCTTCATAAAGGCTTTCCTTATCACTCCAGCCACAA GTGGATTGCTATAGAGAATGACTGTGCCACTCTCAAGGTGTGACAGCAGGATTACCATGG TGCACTCCATTGAACACTCTCAACAGGATACCAATGGGTATCCCAAAGGAAAAACATTTT GTAGGGAAGTGAGTTAAGGAAATGTTGGGTTAAGCAGATTGCTCTGGTAAAACTTGAGCA TCAAAAGAAATAACAGCCATAATGGGCTATAATACATTAAATACAATTAAAACCTATGAG TCCAAATAGAGTCAACAAACAAACAAATGGAAGATATGGAAAAGCTCTTCCTGGCAGAAG AATGTCATCTAATAAATATGATTGGCCATCTTGTAATCAACACAATTGATCCAGTTAAGA ATCATCAATGGAAATTAGTACAGCCACTATGGAGAACAGTTTGAAGTTTCCCCCAAAAAT TAAGAATGGAGCTACCATATGATCCAGCAATCCCACTGCTGGGTATATACACAAAAGAAA GGAAGTCAGTATATAAAACAGATACCTGCACTCCTATGTTTTTTGCAGCATTATTCACAA CAGCCAACATTTGGAAGCAACCTAAGCGTCCGTGAACAGATGAATGGATAAAGAAAATGT GGTACACATACACACTGGAGTGCTATTTAGCCATAAAAAAGAACGAGATCCTGTCATTTG CAACAACATGGATGGATGGAGCTGGAGGTCATTACGTTAAGTGAAATAAGTCAGGTACAG AAAGACAAACTTCACATGTTCTCACTGATTTGTGGGAGCTAAAAATCAAAACAATTGAAC TCATGGAGATAGAGTAGAAGGATGGTATCAGAGGCTGGAAAGGGTAGTAGGGGGTAAGAG GAAAGTAGGGATGGCTAATAGGTACAAAAAAATAGAAAGAATGAAAAAGACCTAGTGTTG GATAACACAACAGAATAACTACAGTCAATAATAATTTAACTGTACATTTAAAAATAACTA AAAAAGTATAATTAGATCATTTGTAACACAAAGGATAAATGCTTGAGGAGATGAATACCA CATTTTCTATCATGTAATTATTACACATTGCATGCCTATATCAAAGTATCTCATGTACCC CATAAATATGTAGATCTACTATGTACCCCCAAAAATTAAAAATTAAAGGTCTTTCCATCT CCCCTTCTTCTCTTTTCTTCTGGTTTTTATGTAAATGTTGCAATGAGCCATCAGTGACTA TGAGATCAAGTGTAATACAGAACTCCTAAAACTCAACAACTATAAAACCCAATTCAAAAA TGGGCAAAGGACTTGAATAGACATTTCTCCAAAGATCTACAAATGGCCAGCAAATAAATG AAAAGATGCTGAACATCACTAATCAGAACTATAATGAGATTTCACCTCATACCCATTAGG ATAGCTATGATCAACGAACAAACAAATAAACAGAAAATAACTGTTTGCAAGGACGTGGAG AAACTGGAACACCTGTCCACTGTTGATGGGAATGCAAAATGATACAGCCACTGTGGAAAA ATAAGTAGGACAGTTCCACAAAAAAGTAAAAATAGAACCAGCATATGATCCAGCAATTCC ACTTCTGGATTTATACCCAAAATAATTGAAGTCAGGGTCTCAGATATTTATACACCTGAG TTCATGACAACGTTATTCACAGTAGCCAAACTGTGAAAGCAACCAAAATGTCCATCAATA GATGAATGGATAAGCAAAATGTGATACATCCATACAATGGAATATTATTCAACCTGAGAA AGGAAGGAATTTTTGACATATGCTACAACATAGGTGAACATTATGCTAAATGAAATAAGC CAGTCACAAAAAGACATACTGTATGATTCCCCTTAAGTGAGGTAGTTTAGTCAAATTCAT AGAGACAGAAAAAATGATGGTTTCCAGGGACTGGGAGAAAGGTAGAATAGGGAGTTATTA TTTAGTAAATTTATAGAGTTTGTCTTAAAAGATGAAAGAAGTTATGGAGGTGGACGGTGA TGATGGTTGCCCAATATTATGAATGTATGTAATACCACTGAACTGTACACATAAAAATGA TTAAGATGGTAAATTTTATGTATTTTACCACAATAAAAATTATTTAAAAAAAGAATATCA ATGGATACTCAAATTAGTGGGTGAAAATTTGATGAACAAGAATTTGTATCATTCCAAATT ATCTTCTCACATAGCCTCTATTAATTATAAAGGTAAAGAAAAGTTACCTTACAGTGAAGA AACGTGGTGGATAACACCTTAGCCAAGTCACCAAAGTTCGCATCACAAAAAAGACCCAAA AACTGACGTTAAAAAAACAAACATAATGACAGAATGCAGTGAGAAAAACACATTACTTCT GTGGTATTCCTGCCCCCCAAATGCAGACTCTGAATCTAATTACAAGAAAGCATAATACAA TTCAATGTGAGGAACATTCTAAAAAAAAACTGGCCTGTTCTTTTCAGAAACACCAATGTC ATGAAAGGAAAGCTGAGGAGCTGTTCTAGATTAGAGGAGACTAAAGACATGGCAACCAAC TGCAAGGCGTAATCTTGGATTCCGGGCTGGGGTTGGGGAGTTATAAATGCCAGTATTGGG AAAATTGGAATACATTTGCATAAAGTTTATAGTATTACACCAAAGCTAAGTTTCTTGATT TCTATAAATGGACTACAGTTTTGTAAGAATATATTTATTCTGGCCAGGCGCGGTGGCTCA CGCCTGTAATACCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACAGGTCAGGAGTTCAA CATCAGCCTGGCCAAGATGGTAGAACCCCAACTCTACTAAAAATACAAAAACTTAGCCAG GCACGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGACAATTGCTTG AACCCAGGCGGCAAGGTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGA CACAGTGAAACCCTGTCTCAGGAAAAAAAAAAAAAAAAAGAATATATTTATTCTTAGGAT AAGAGCTAAAGGAACATGATGTCTGAAACTTACTGTCAAAAGGTTCAGAAATCTATCTTA TACTATATATTCATTTATATTAATTATGTACATTAATATATAGAATTATTTACGTACTTA TAATACATACATGTGTATCTGTGTGTGTGTCCAGAGTGAGAAAGAGAGAATAATAAAGCA AATGTGGCAAAACATTAACAGTTGGTAAAGTACATAAAGGGTATTTAGTATTTCCTTGTA TTCTTCTTGCAGTTTTTCTTTAAATATAAAATAATTGTAAAATACAAAGTTAGAGAAGTA ATTTATTTACTACAGGATTTCTCAAAGTTTTAAAAATTCATCCACTTATTCCATCCACAC TAGTTGGACACCTACTGTATACCATGCACTGTGCTAAGTGGTTTAAGAATATCCAAGAAG AGCATCTCATGCTGCTAGTTTTCTGTGAAATACATTTCAGAAGGTATTACTTTGTCTAAT TATAATCCATCTCTCTAACTAGTATATGGGCTCCAGAATGGCAAATGCCTGATCTTGGAG ATCTTATTCCCCCAGTGCATATCCTGTTGTCTGAGGCCTCAGAAGGAGCTTGATAAATGT TGACTATATGGGGAGTGAGCAAGTGAATGATGAGTAAGTGAGTGAGTGAGTGAGTGAGTG AGTGAAAGTCACCGTGACGATCTCTGTAGCTGACACTCACTTCTTGTGGGGATCACTCCT GGACACCTTTGGCTGCACCCAACCTGCCAGATCCTCCCAGATTCTTCCAGGTGCCACAGT CTCAGCTAGACAGAGTGACTACTCAGAAAAGCTAGAATGCTGCCTTGCAAAAAGGCTGTC ATTACAATAAAAATAAAATACTGGACAGCTCTTTCCCTTTGACTCTGACTCTAGAACAAA AGAAGATGTGAATGAAAACAATAGTCATCAAGGCTCATCACCACCACAGAAGGCCCTAGA GGTATTCGACTTCTTGCATCGAACACCTTCTGCAGGACCCCATTTAGTGAAGCCAGAGTC CTGGACAGTGGTACAAAACAAGGAGAGGAGTAGGCTCACATTTAAAAACCAAACACTGCA TGTTCTCACTCATAGGTAGGAATTGAACAATGAGAACACTTGGACACAGGAAGGGGAACA TCACACACCGGGGCCTGTCGTGGGGTGGGGGGAGAGGGGAGGGATAGCATTAGGAGATAT ACCTAATGTAAATGACGAGTTAATGGGTGCAGCAAACCAACATGGCACATGTGTACATAT GTAACAAGCCTGCACGTTGTCCACATGTACCCTAGAACTTAAAGTATAATAATAAAAAAA AAGAGTCACTAAGTTCTTACAGCTTCTTTGGTAACTACTTTGCACAATTCCTGTAACAAA AGGTCTAGAATATCTTCTGAATAAAAATGAGGACAACTTTCTCACAGCTGCCATTGTTTA CCCAGGAATTCCCTTGCTTGGTCTTGTTTTTACAGCATTGCTTTCACATAATTACTTTCT GCATTGCCCCTCTACCTTTCTTGCAGTTTCTGAAGATGCTACATCATTATAAATTACAAA CATGGATATTCATCACAGAAACTGGCAGTAGTAGAAGCTTCTAGAAATAATAGGATTTGA TGTGATGGTACCATCGAAAAATTTAAAATTACTCTCCTAAAGTGAAAGTAAAATGCAAGG GAAAATAATTTTCCCCAAGCCAGATTTACCTTGAAATTCTTCTTTCTAGATTTAGTGCAT AACAGCAAGCCATCCCTGAAGAAGAGCAGAAACTTATACTTTTACAGGTTAACCAATGGT TTGGTTTAATAAATAATAAAACCTCAGAGTAAGACATGACCTTGGACGTCATTGAATCTA GCTGTTTACCCAATGTAAAAATTACTAATAAAAATTCCAGAGATGGCTTTGTGTAAGTAG CTCTCCTAGAAAGCCAATTGCACAATGGTTTCCTAGATTTCTACAATGTAATTGCTGAAG GAAAGAAGTTGTTTGAAATGCTGGATGCAAAATCTTACACTTGAAAGCTTTGCCCTACTT CTTGGGTTGGTACCAGGTGCCAACCCTGAAAAGGATGCAGCTCAGAGAGGAAACTCTGAA CCCAGAAGAACATGGCTGTCCCCATTCCCCAGCACTTCCCAAAGGCACCACTCAAAGAGA GTCCATCAATCTTTGGAGCACTGACGTTGAAACAGTTCATGAAATTTCTTTTACAGTCAC CCAAACACATCCTGGAAATTTAAGACCTAGGAGTCCAGTGAAGCACATTATTGTTCTTGA AAATTATACCAAAAGTCACTCAAAATTACATCAAAAGTTTCTCAACTCAATGCAAAAATG CCAATATAGAAAGACAAATAAAATTGCCCTTCTTTGGGGGACACTTTGGGCACATTCATC ACGCACAGTCCACACAGTAAGTTACAATGTGCAACTATGGGACTCTTTTACTATCCTTTT CATTCCTAAGTGGGAAGTTGAACAGGTATGAGCATCTCAGCAGTGTTGTAGGAGGGCAAA TGGAGGCTAGTGACCATGTAATATGCTTGCCCCCTCTCTCTCTGCACCACATTAAAATTT GCAAAGATTCTCACTCTTGTCCAAGGGCTGGTACCCATGTCACCTTCCCTAAGTCCCTGT GTACCAATAAGGTAAATTCAAGTAGGTAACAGATTTGCAGCTTACATGTAGAACTCACTG TGTGTGGGTGGGGAGTGGGGGGAATGCAGGAGATGCCCTTTATGAAAAAAAAATTGTGGT TTGCCACAAGGTGTCAGTATATGTCACCTCACAGTGAATCAGGACTGGCTGTTAAACCTA TATATATAATATATTAGAATCAAAGGCTGCGTACATCTTATATCCTGATAAAAGCAGGAA AACACATTCCTGTTCCTTCTCTCTGTAAAGAGAGCAACGTAAATTTTAGGATATATTTGA TTAAAGACAGAAATAGAAGTGTGGTGATGACCTCAAATCTCACCTAGAACTCAACTCCCC TTTCTCATTCTGTGCCAATCTCCACTACTGCAGAGAGTTGGCAGCTAGCTCACAGATGCC TCTCTGCTTGCCTCTCTCTCCCTCATTCTTTGGCCTCTGAGTATCTTGTCTGTGCTCTAG CCCCGAGAAGGTCTTCTTCCCTAATGTTACCAAAATGCAGCGACACCTTTAAAGCGAGAG AGAGAAAGACAGAACAAGTAAGAGGGGACAGGAAAGACAGAGAACAAGATATGGCTCTGC CAGAGGACACATTTCCCCTCCCAGGGAGAAGGGACACAAAACCAAAGGTCAGCTCCTACT TACCTTTCTGCCATTCACAAAGAAAACCAATTTGTCTGCTGTCATTGTCACAGGTTGGGG TCCCCGAACTCCAGGTACCTCACTCCTAAGAGACACTGGCAGGTAGTTATCACTGCTCTG T bcftools-1.21/test/csq/ENST00000379416/ENST00000379416.fa.fai000066400000000000000000000000211467060157400215440ustar00rootroot000000000000002 80521 23 60 61 bcftools-1.21/test/csq/ENST00000379416/ENST00000379416.gff000066400000000000000000000332231467060157400211740ustar00rootroot000000000000002 Ensembl chromosome -31334220 210859308 . . . ID=chromosome:2;Alias=CM000664.2,chr2,NC_000002.12 2 ensembl_havana gene 100 80521 . - . ID=gene:ENSG00000158125;Name=XDH;biotype=protein_coding;description=xanthine dehydrogenase [Source:HGNC Symbol%3BAcc:HGNC:12805];gene_id=ENSG00000158125;logic_name=ensembl_havana_gene_homo_sapiens;version=10 2 ensembl_havana mRNA 100 80521 . - . ID=transcript:ENST00000379416;Parent=gene:ENSG00000158125;Name=XDH-201;biotype=protein_coding;ccdsid=CCDS1775.1;tag=basic;transcript_id=ENST00000379416;transcript_support_level=1 (assigned to previous version 3);version=4 2 ensembl_havana three_prime_UTR 100 1736 . - . Parent=transcript:ENST00000379416 2 ensembl_havana exon 100 1787 . - . Parent=transcript:ENST00000379416;Name=ENSE00001480902;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001480902;rank=36;version=3 2 ensembl_havana CDS 1737 1787 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 3420 3596 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037202;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037202;rank=35;version=1 2 ensembl_havana CDS 3420 3596 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 5268 5456 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037243;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037243;rank=34;version=1 2 ensembl_havana CDS 5268 5456 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 7108 7173 . - . Parent=transcript:ENST00000379416;Name=ENSE00001625471;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001625471;rank=33;version=1 2 ensembl_havana CDS 7108 7173 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 7962 8076 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037184;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001037184;rank=32;version=1 2 ensembl_havana CDS 7962 8076 . - 1 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 10463 10515 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037194;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001037194;rank=31;version=1 2 ensembl_havana CDS 10463 10515 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 12548 12622 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037245;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037245;rank=30;version=1 2 ensembl_havana CDS 12548 12622 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 13301 13429 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037176;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037176;rank=29;version=1 2 ensembl_havana CDS 13301 13429 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 14047 14142 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037213;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037213;rank=28;version=1 2 ensembl_havana CDS 14047 14142 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 14678 14759 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037238;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001037238;rank=27;version=1 2 ensembl_havana CDS 14678 14759 . - 1 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 15465 15610 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037188;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001037188;rank=26;version=1 2 ensembl_havana CDS 15465 15610 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 15811 16002 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037226;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037226;rank=25;version=1 2 ensembl_havana CDS 15811 16002 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 29937 30023 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037219;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037219;rank=24;version=1 2 ensembl_havana CDS 29937 30023 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 31236 31323 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037183;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001037183;rank=23;version=1 2 ensembl_havana CDS 31236 31323 . - 1 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 31755 31888 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037207;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001037207;rank=22;version=1 2 ensembl_havana CDS 31755 31888 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 32649 32773 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037200;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001037200;rank=21;version=1 2 ensembl_havana CDS 32649 32773 . - 2 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 33740 33836 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037191;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001037191;rank=20;version=1 2 ensembl_havana CDS 33740 33836 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 34320 34439 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037230;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037230;rank=19;version=1 2 ensembl_havana CDS 34320 34439 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 36134 36257 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037186;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001037186;rank=18;version=1 2 ensembl_havana CDS 36134 36257 . - 1 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 38007 38176 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037179;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001037179;rank=17;version=1 2 ensembl_havana CDS 38007 38176 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 39652 39735 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037197;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001037197;rank=16;version=1 2 ensembl_havana CDS 39652 39735 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 41159 41333 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037193;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001037193;rank=15;version=1 2 ensembl_havana CDS 41159 41333 . - 1 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 42832 43016 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037192;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001037192;rank=14;version=1 2 ensembl_havana CDS 42832 43016 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 45646 45755 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037216;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001037216;rank=13;version=1 2 ensembl_havana CDS 45646 45755 . - 2 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 47412 47505 . - . Parent=transcript:ENST00000379416;Name=ENSE00001037174;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001037174;rank=12;version=1 2 ensembl_havana CDS 47412 47505 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 48780 48931 . - . Parent=transcript:ENST00000379416;Name=ENSE00003687416;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003687416;rank=11;version=1 2 ensembl_havana CDS 48780 48931 . - 2 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 49534 49626 . - . Parent=transcript:ENST00000379416;Name=ENSE00003598209;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003598209;rank=10;version=1 2 ensembl_havana CDS 49534 49626 . - 2 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 52193 52334 . - . Parent=transcript:ENST00000379416;Name=ENSE00003641759;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003641759;rank=9;version=1 2 ensembl_havana CDS 52193 52334 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 53590 53676 . - . Parent=transcript:ENST00000379416;Name=ENSE00003581429;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003581429;rank=8;version=1 2 ensembl_havana CDS 53590 53676 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 54006 54074 . - . Parent=transcript:ENST00000379416;Name=ENSE00003653832;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003653832;rank=7;version=1 2 ensembl_havana CDS 54006 54074 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 63447 63508 . - . Parent=transcript:ENST00000379416;Name=ENSE00000962554;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000962554;rank=6;version=1 2 ensembl_havana CDS 63447 63508 . - 2 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 64352 64478 . - . Parent=transcript:ENST00000379416;Name=ENSE00000962553;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00000962553;rank=5;version=1 2 ensembl_havana CDS 64352 64478 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 66999 67107 . - . Parent=transcript:ENST00000379416;Name=ENSE00001144504;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001144504;rank=4;version=1 2 ensembl_havana CDS 66999 67107 . - 1 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 68827 68923 . - . Parent=transcript:ENST00000379416;Name=ENSE00001190982;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001190982;rank=3;version=1 2 ensembl_havana CDS 68827 68923 . - 2 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 71686 71743 . - . Parent=transcript:ENST00000379416;Name=ENSE00001190992;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001190992;rank=2;version=1 2 ensembl_havana CDS 71686 71743 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana CDS 80404 80445 . - 0 ID=CDS:ENSP00000368727;Parent=transcript:ENST00000379416;protein_id=ENSP00000368727 2 ensembl_havana exon 80404 80521 . - . Parent=transcript:ENST00000379416;Name=ENSE00001190986;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001190986;rank=1;version=5 2 ensembl_havana five_prime_UTR 80446 80521 . - . Parent=transcript:ENST00000379416 2 havana lnc_RNA 48780 55412 . - . ID=transcript:ENST00000491727;Parent=gene:ENSG00000158125;Name=XDH-203;biotype=processed_transcript;transcript_id=ENST00000491727;transcript_support_level=3;version=5 2 havana exon 48780 48931 . - . Parent=transcript:ENST00000491727;Name=ENSE00003672481;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003672481;rank=6;version=1 2 havana exon 49534 49626 . - . Parent=transcript:ENST00000491727;Name=ENSE00003607472;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003607472;rank=5;version=1 2 havana exon 52193 52334 . - . Parent=transcript:ENST00000491727;Name=ENSE00003603025;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003603025;rank=4;version=1 2 havana exon 53590 53676 . - . Parent=transcript:ENST00000491727;Name=ENSE00003555606;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003555606;rank=3;version=1 2 havana exon 54006 54074 . - . Parent=transcript:ENST00000491727;Name=ENSE00003496520;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003496520;rank=2;version=1 2 havana exon 55375 55412 . - . Parent=transcript:ENST00000491727;Name=ENSE00001844334;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001844334;rank=1;version=1 2 havana lnc_RNA 48861 50174 . - . ID=transcript:ENST00000476043;Parent=gene:ENSG00000158125;Name=XDH-202;biotype=processed_transcript;transcript_id=ENST00000476043;transcript_support_level=5;version=1 2 havana exon 48861 48931 . - . Parent=transcript:ENST00000476043;Name=ENSE00001856457;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001856457;rank=3;version=1 2 havana exon 49534 49626 . - . Parent=transcript:ENST00000476043;Name=ENSE00003607472;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003607472;rank=2;version=1 2 havana exon 49864 50174 . - . Parent=transcript:ENST00000476043;Name=ENSE00001813822;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001813822;rank=1;version=1 bcftools-1.21/test/csq/ENST00000379416/ascii-art.txt000066400000000000000000000004641467060157400212770ustar00rootroot0000000000000053590 | 01234 5 CAGCA--ACTCTGG.. ref CAGCAGCTCTCTGG.. alt GC T CDS: 53590-53676 - CAG|CAA|CTC|TGG|GGG|.. ref L L E P P GCA|GCT|CTC|TGG|GGG|.. AA>AGCT C S E P P GCA|GCA|CTC|TGG| A>AGC C C E CAG|CAT|CTC|TGG A>T L M E bcftools-1.21/test/csq/ENST00000379416/compound.cmd000066400000000000000000000015031467060157400211660ustar00rootroot00000000000000{bin}/bcftools csq -B 3 -f ENST00000379416.fa -g ENST00000379416.gff compound.del-snp.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -B 3 -f ENST00000379416.fa -g ENST00000379416.gff compound.ins-del.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -B 3 -f ENST00000379416.fa -g ENST00000379416.gff compound.ins-ins.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -B 3 -f ENST00000379416.fa -g ENST00000379416.gff compound.ins-snp.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -B 3 -f ENST00000379416.fa -g ENST00000379416.gff single.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENST00000379416/compound.cmd.out000066400000000000000000000011061467060157400217730ustar00rootroot0000000000000053592 GC G @53595 53595 A T frameshift|XDH|ENST00000379416|protein_coding|-|216LLR..1334>216I*|53592GC>G+53595A>T 53594 A AGC @53595 53595 ACT A missense&inframe_altering|XDH|ENST00000379416|protein_coding|-|215EL>215VL|53594A>AGC+53595ACT>A 53594 A AGC @53595 53595 A ACTC frameshift|XDH|ENST00000379416|protein_coding|-|216LLR..1334>216ECC*|53594A>AGC+53595A>ACTC 53594 A AGC @53595 53595 A T frameshift|XDH|ENST00000379416|protein_coding|-|216LLR..1334>216SC*|53594A>AGC+53595A>T 53594 AA AGCT frameshift|XDH|ENST00000379416|protein_coding|-|216LLR..1334>216SC*|53594AA>AGCT bcftools-1.21/test/csq/ENST00000379416/compound.del-snp.vcf000066400000000000000000000005411467060157400225430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 53592 . GC G . PASS . 2 53595 . A T . PASS . bcftools-1.21/test/csq/ENST00000379416/compound.ins-del.vcf000066400000000000000000000005441467060157400225370ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 53594 . A AGC . PASS . 2 53595 . ACT A . PASS . bcftools-1.21/test/csq/ENST00000379416/compound.ins-ins.vcf000066400000000000000000000005451467060157400225650ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 53594 . A AGC . PASS . 2 53595 . A ACTC . PASS . bcftools-1.21/test/csq/ENST00000379416/compound.ins-snp.vcf000066400000000000000000000005421467060157400225710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 53594 . A AGC . PASS . 2 53595 . A T . PASS . bcftools-1.21/test/csq/ENST00000379416/single.vcf000066400000000000000000000005151467060157400206400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 53594 . AA AGCT . PASS . bcftools-1.21/test/csq/ENST00000381157/000077500000000000000000000000001467060157400166515ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000381157/ENST00000381157.fa000066400000000000000000001533221467060157400210110ustar00rootroot00000000000000>X X:2746809-2800879 CCGGCGGTTCCCGGGTCTCTCTTCCCGGCAGCCGGGGCTGGGCACCAGGCGGCGCGCGGG CTTGCGGGCAGGGGCTGCAGGGAGGAGGAGAGGACCCGCGCCCGCGGGGGCTGGCGGAGG CGGGGCCGGGCTTCCGGACAGAGGCCAATCGCTGCCCTCGGGGCCTCCAGCGCCGGCTCT GGGCCGAGGCAGCCAGAGCGCGGAAGAGGTGCGGGGGGCTGTAGGGGGCTGCAGGGGACC GTGGGCAGTGGAGGAGGCCTGGGCGCGGCGGGGGGCCGGGGGGCGCAGAGGCTGCCCGAA CGCCTAGGAGGTCTCGAGGGTGGGTGGCGTACAGCGGGGCGGGGGCGCAACCCAGAGGCC GAGGCTGGGGGCTGGGGGAGGGGCGCCGGACTGGAGTGCAAAGGAGGGGCGAGGGGCGCA GGGGGCTGGAGGTCAGAGGTTGCCCAAGCGCGAAGGAGGGGAGGGGTGCGGGGCGCGGGA GTAGGCCAGGAGCGCTTAGGGGTGAGTGCGCCGAGCCAGGGCACCGAGTGCTGGGGAATA CAGGCCGTCCAGGCGCGGCGGGGCGCGGGGAGACGGAGGCTGCCGGAGTACGGAGGACAG ACGGGGCGCGGGCGTAGGGCTGGGAGGCTTGGGGAGGGGGGCGCGGGCCCAAGGCAGAGG CTGCGGGAGCGCGGGGCAAGGGAGAGGTGCAGAGCGTGGAGGGGGCTCGGGGGCGCTTGG GGAGGATGGGCGGCAGGCCGGGTCGGGGAGGAGGGGCGGCGAGAGGCGCAGGGGTAGGCC GGGGGGCTGCACTGGAGTGACGAGGGAGGGGGCACCTGGCCGGGGGGCGCGGGCAGAGGC AGCCCAAGCTCGGAGGAGGTGCAGATACTGGCGTCCGGGAGCGCAGGGGTGGTCCAGGGA GTGGAGAGGGGTGACCGGGGGGCGCCAGCTGGGGTGGAGGAAGAGGATGCCCAGAACTCC AAGCAGGTGCGCGGGGCGGCGGGGCAGCTGCTGACACCGCTGAGGTCGGGTGGTGTCCCG GGGGCGTTGTCGTTGCTGGGCGCATGGGTGTTAAGACGCAGCGGGGTCGCAGGTGACTGT GGGGAGGACAGGGGGTCAAGGGGCCCCTGGCCAGAGGGCACGAGGCTGACCTGGAGCGCC AAGGAGGAAGTGCGGGGCGTGGAGGTCGCAGGGGCATCGGGGGAGGCAGGGGCCCCGTGG GGCGCAGGTGACATGGAGTGGGTAGGAGGCCGGGGGTGACACTGGCGGGGCCTGCAGCCG AGGGTGTCGAGACTGCCACGCTGTCGCCCCCAGGCCTGGAAATCCACGCGGATTCCCGGA GACGGCGCCTCTGCTCTGCGGGTTCGTGGCGAGGAAGTCCACCCACTGCTCCCGGGCGCA GGTCTGCAGGTCCGCGCCCACTGCCCGCGGCGCCACTGACCATGTCGGGTGAGTAGCTCA AGCTGCTTCAGTTCAGCCTGCCTGTTCCTACTGGCTTGGGTGACAGATTGGTCTGCACTG GGGAGAACCCCACTTTGACCGCAGGATTGCCCCAAACCCCGAGTCTCCCCCTTACTGCCT CGCCCAGGTCTCTCTGGGGCTGGAGGGAATGGAGATACCAGCCTCAGCTGCTGGGAGGGG GTGATTTACAGCAAGTGAAGGGGGCCTTGGGATTTCACCAGTTTCCTTTTGTAAAATATA GTCCTGAAACTTTCAATGGGCTTGTTTCTTGGGAATAGCATTGAACTGCCTGAGACTGTC ACTGCCTGGAAGGCCGATGGGAAGAAGTCTGTTCTCCTGAAATGGCCCTAAAGCTCTGGG AAGAGGCTGCCTTGAGTTCTTAGAACTCAGACCACGGTTTTAATTTCTGTTTCCAGTACA GATACAGGGATGGCCCGGCTTGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAAGCTG AGGCGGGAGGATTGCTTGAGGCCAGGAGTTTGAGACCATCCTGGGCAACATAGGGAGACC ACATCTCTAGGAAAAAAATTTAAAAATCAGCTGGGCATTGCGGCACCTGCCTGTAGTCCC AGCTACTAGGGAAGCTGAGGTGGGAGGGTCCTGAGCCCAGGAGTTCCAGGCTGCAGTGAG CTATGAGTGCACCACTGCACTCCAGCTTGGGTGACAGAGTGAGACCCTGTCTCTAAAAAA CAACAACAAAATAAGAATCCAGGTTAATCCTCCTGCAGGCAGAGGGCTGGCTGGCAAGAA TGGCAGGAAAGGCCTGCCCCCGCCAAGGACCGGTGAGCCCCATCTCCCTGCCCTTGGGTT TTGTGGACATCAGATAGACTGGTTGACTTAAGAGGCCTAGATATGTGAACAGAGTGTAAC CTCTTCCCATAAGAAAGATGCTGGTTCTATTTTCTATCATTAAATCATTAAGACACCTCC TTCTTGTACCAGACCACACTGGATCATTCTATGAGTGCATTTTATGTATTTATTTTTAAA TGTATATTTTTTAAATTTTGTAGAGACAGGGTCTTGCTATGTTGCCCAGGCTGGTCTTGA ACTTCTAGGCTCAAGCAGTCCTCCTCCTTTGGCCTCTCAAAGTGCTGGGATTACAGGCAC GAGCCACCACGCCTGGCCATGAGTGCAATTTAAAACACACAAACAGAACAGATGACTTTT TTATTCAGAGGAGAGATTTGGTAAATCACAGAGCTGCTTCTCTCCTGTTTGTTCCCACTC TGGACTTAGAGATGAAAATTGTCGGGGCAGGGATCTTAAGGGCTGTTTTCATGAGGTGTA CTGGAAGAGTCTGTTCCAAGGAATGGCAGAAAAGATTCTCTGTTCTAGGGACGCGTTTGG AGCTCTCTAAAGTGAAAGCCACACATTTCCCCAAGCCTGCTAGGGTCTGTATAATAGCAG CATTCAAGACGGACATTCGCATACATCTTGGTCAGCCTCGTGCCAGAAGAGAAGACTCAA CTCTTTGCAGAAAACAAAAACCACCTTTGAGTAGAAAAGGGCTGAGAAGGAAGCTGCTAA GGTTATTTTGGGGGGTGATCAGAAGATTCCTTGAGTGCAGGGGGGCAGGCAAGGGGTAGA AAGAAACTGTTGTCACAGATTCATAAAATTCTCAGCCACTGTAATCTCCAGACTGGACTT GATTTTGTGACAATGTCTCCTTTTTGTGGGCTGTGGTGCAGTGACAGGTTTTCTTGCTGT TTTTCCACTCCATGCCGTTGCTGAAAGTGTCCGCCGCAGTGGCACTTGGAGTGGAAACTC CCTCTTTGAATGCAGTAGCATTGGATAATTGTGGATGTTCTCTGGCGTCTGGCGCCGCAC CAGGACTTGATCACCAGTTGTTTCTTCAAGGCAAGGCGATGTGGAAGCTAAGCCCTGTCA ATCAATGTTTCATCTTCTGTTCTATTTCAATCTGCTGGTCTGTCTTTGCACTTTAGATGG GTTTTACAGTGTCCTGGATGGGAAGCGGCTAACCTTCAGGAGGTGCACATTTTTGTTCCA AAGCAAAAGTCTGAGTCTCGGATCCCTTGTTGCTGGAGAGAGCTCGTGTGCCAACTGGTG TTGTCTTGTCATTGTGTGACTGTGGTCAATATTCCCTCCACTCTAAACCAAAGAGAGAAA CAGGGTATCCAGTAGTTCCATAAAACTCTCACTCTAAATGCAGCCCTGTCTGCATTCTCT TTTGTGTTTGAGATCAAGGTGGGTGTGGGCAGGGCTGGTTCCTCCTGAGGCCTCTCTCCT GGGCTTGGTCCTCACAGGGTCTTCCCTTTGTGTGTGTCTGTGTCCTAATCGCCTCTTTTT TTTTGAGATGGAATTTTGCTCTTGTCGCCCAGGCTGGAGTGCGATGGTGCAATATCGGCT CACTGCAGCTTCCGCCTCTTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCT GGGATTACAGGTGCCCGCCCCCATGCCCGGCTCACTTTTGTATTTTTAGTACAGATGGGG TTTCTCCATGTTGGTCAGGCTGGTTTTGAACTCCTGACCTCAGGTGATCCACCTGCCTTG GCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCACGCTTGGCCTAATCTCCTTTCT TATAAGGACACCAATCCTATTGGATCAGAGCCCACCCTAGTGACTTAATTTTATCTTAAT CTCTTCTTTAAAGACCCCATCTCCAAATACAGTCACATTCTGAGGTCCTGCAGGTTATGA TATTCATATATGAATTTTGGAGGTGCACAAGTCAGCCCATAATAGGATAACTCATTTATT TGAATACTACTGTGTTTTTCTGCTGGGGCTGCCATAACAAAGTCCCACAGACTGGGCGGC TTAAACAACACACATTTACTCTCCCACAGTCTTGGAGGCTGGAAATCTGAGATCAGGGTG TGGGCAGGGCTGTTTCCTCCTGACGCCTCTCTCCTTGGCTTGTAGATGTTGTCTTTCTCT GTATCTCCACAAGGTCATCCTTCTGTGTGTGTGTGTGTCTGTGTCCTCATCTCCTCTTGT AGTGAGGCCAGCAGTGCTACTGTATTAGGGCCCACCCTAGTGACCTCATTTTACCATAAT CACCTCTTTAAAGACCCCATCTTCAAATGCAGACACATTCAGAGGTTCTGTGGGGTAGGG TTTCATCCTAGGCGTTTCAGGATGGGTTATCATCCGTCTATAACACCCATTAATCCTCAT GTTTTCCCTGAGGTCCCCATGAAGAGCTATAAAGCCAGCGCATGTGGTTATCAATCAATG ATCACTCTGCCATTTCTCTTAGTTGTCACTGAGATCCTCATGAAGAGATTAAAAAAACCA GCGCACATCGTTATCAATCATTGATCACTTTGCCAGTTCGCATAGTTGTCACTCACGTCC TGATGAAGAGATAAAAAGCCCATGCGCATGGTTATCAATCATTGATCACTCTGTCATTTC TTTCAGTTGTCACTGAGATCCTCATGAAGGGGTAAAAAACCAGAGCCTGTGGTTATCAGT CACTGATTGCTTTGCCATTTCTCTTAGTTGTCACTGATGCCCTCATGAAGAACTATAAAA CCAGCACAGGTGGCGATCAATCACTGATCACTTTGCCATTCCTGTGTGTTGTCCTCTGCA CCTTGCTTTGGGCCAATTCACTTGCATCATCCTTTTCTCTAGACAGCCAGAGGGCCCTCC CTGGCAATGGAGATGAGACCTTCTTACAGGTTTTGGAACCCTCAAATAGCTCCTCATAAG CCTCAGGATAATAGAAAAGGCTGCATATCACCTTTGTAATCCGGGCCCTCTGACCCCATC TCTTCCTGTGGGTCCTTGTTCTCCAGCTGCTGTTGCTACGCTGTGAGGAATGCAGGATGC AGCATGCAACCTATCATCTCCACCTCTGGCCTTGGCTGGTGGATTTTTTCTGCCTCTTCC TTCTTTGCCTTATTATTTTTGGTTCAGTTTCTTATTGGAGGCAGGAGACAGTAGCTATTT TGAGGGCTTTTGTTGGTGTTGGAGTCAGAGGTGACCTCGGACATTTAATTACTCGTTGAA GCCCCGGTTTACTTGTTTTTGAAGCACATGTCTGTGTTGGAAAGGGAATTAATGAGAGCG CAGAGGTATGCCCTATCTACACACTCCTGGAGGGATGGGAGCCATATTCATTCTTGTTTG TTGCTCCACTGATTTCTTGATGGATAAGTTCTTCCTGGCCATTTATCCCTGAGCTTGGAT GGTGCCCTTTCAAAAACTGCTGCCAGCCATAGGACTTGCCTTGCAGTATCGAAACACCCA TTTCTTAGGGCTAATGTTTCTCATGGAGCTGTGGGTGTCTGAGGACAGAGCTTGTACCTT GTCAGCTGCTGGGCCCAGCACCTAGCAGATTCTCGTGCCTGGGAATTGCCTGGGACGTGA ACCCACAGTGAACGTGTAATGCACTGAGAGCACGTCATTAGGCCCACACAGACATCTTCT GCCCCTTCACCTTCTTTGTCTTCTGCCTCCAGCTTCAATCCTTCACTCTTTCTCTAAGCA GATGCCCTTATGTGTGCAGCTTATGGCATAGCACTGTGGACTGGGATAAGCAGTGTCCCC CATAAAACTCATGTCCCCCCAGAAGCTGTGAATGGGACCTGTGAACCCAAAAGTATCTGA GACAGGTCTCAATCCATTTAGAAAGTTTATTTTGCCAAGGTTAAGGACATGCCCGTGACA CAGCTTCAGGAGGTCCCGACAACATGGGCCAAAGGTGGTCGGGGTACAGCTTGCTTTTAC ACATTTCAGAGACATGAGACATCAGTCAATACATGTAAGATACACATTGCTTTGATCTGA AAGGGTGGGACTACTTGAAGCAAGGGGGTTGCGGGGGGTGGTGCCAGGTCATAGGTAGAT TTTTAAATGTTCTGATTAGTCGAAAGAGTTATTATCAATAGAAGAGAATGTCTGGGTTAT GATAAGAGGTTGTAGAGACCAAGGTTTTATCACGCAGATGAAACTTCCAGGTAGCAGGCT TCAGAGAGAATAGATTGTAAAGGTTTCTCATCAGACTTGAGGTCTGTGTGGATGTTTATG GTGGTCAGCTTTTCCTGAATTCCAAAATGGAGGAGGTTATGATGAGGCATGTCTGACCCT CTCCTCATTATGGCCTGAACTCGTTTTTCAGGTTAACTTTGGAATGCCCTTGGCCAATTA GGTAGTTGCGAGGCCTAGAATTTTAGTTTAGGTTTACAGACCTTATTGGGAAATAGGGTC TTTGCAGATGTAATTAGTTAAGCATCTCAAGATAAGATTATCCTGGAATATTTGGGTGGG CCCTAAATCCAATGGCAGGTGTCCTTCTAAGAGATAGAAGAAGAGACACAGACACAGAGG AGGCCATGTGGAGTTGGAGGCAGAGATTGGAGTAATGTGGCCACAAGCCCAGGGACATCT GGAGCCACCAGGAGCTGGAAGAGGCAGGAAGGACCCTTCTCTAGAGTTTGGTTTTGGAAT CCTGGCCTTCAGAACTGCAAGAGAGTAAATGTGTGTTGTTTAAGTCTCCCAGCGTGTGGT ACTTTCTCACAGCAGCCCCAGGAAGCTCATTCATGGGTTTGCTAGGGAAAGGAGTCAGCG ATGAGCCCACCAGTAAGCAAAATGAGCACAGCAGGTAAGATGGCACAAGAGATGAAGGGT CCTGTGTCATAGGAGGTGAGGGACTGTGATGAGAAGGGTCGTCTTGGGGAGCAGGGTTTG CAGGAAGATCTCTGAGGGATGGGTGGTTTTTTCCATGGCCACCATGTGCTGGGAGGAGAG CAAGTTCCAGGTGAGTTAAGGGAGTGGTAGTAGCCCCATGGTAGTAGCACACATCATAGG ATGTGCTTGAAGACCCAGAGGGGTTGAGCTGGACGTGGGGACTGAGTGTGGGGGATGAGA TGACCAGCAGTCTGGACCCAGCTTACATTTGCAGACAATGAGAAAACCATTGGCGTTGGG TTGGCTTTCAGGGCAGCTGATGGCTTTCACTGTGTGTTGGGGGAGAAAATGTGGTTTTTA AGGACCGAGGAGACAGATAACAGGGACCAGAATCTACAGGGTGGAGCAGAGAATGCAAAG GAGGGAAGCTGTGGCTCAGGGTGGTTGATGCAGAGACCCATTTTAAATGTTTTCTAGTCT GGTGCGGTGGCTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCAGGACGGGAGGAT TGCTTGAGGCCAGGAGTTTGAGACCAGCCTGGGTGACAGAGCAAGAGACCCCATCTCTAC AGAAAAGTTAAAAATAAATTAGCCAGGTGTGGTGAGCATCTGTAGTCCCAGCTACTCAGG AGGCCAAGGCAGGAGGATAGCTTGAGCCCAGGAGTTCCGGGCTTCAGTGAGCTGTGATGC TGCTGCTGCACTCCAGCCCTGGTGGCAGACAGAGCAAGACCCTGTCAAAAAAAAAAAAAA AAAAAAGCCAGGCACAGAAGGACACCTGTAGTCCCAGCACTTTGGGAGGCTGAGGCGGGT AGATTGCCTGAGCCCAGGAGTTCGAGACCAGCTTGGGCAACATAACCTGTCTCTACCAAA AATATAAAAAATAGCTGGATGTAGTGGTGTGCACTTGCGGTCCCTGCTACTCAGGAGGCT GAGGTGGGAGGATTGCTTGCTCTCAGGAAGTCGAGGCTGCAGTGAGCTGAAATCATATCA CTGCGCTCCAGCCTGAGCAACAGACGGAGACCTTCTCTCAAAAACCACCACCACCACAAC GTAATGAACAACCCCAACATTTTCTGTTGTGCCTCTCGGTTAAGATCTCAGGTTAGTTAT GCAAGAGTAGAATGTGGGATTGGAGGCAAGTGGACTTCTCCTTACCCCAGAATTCATGTC ATAAATGCTCTGCACAGACGAGGCTTCTGGGACTCTTGGGGAGACCTAGGAGGTGGGTAA TAGGGATCTGAATCTACACGGTGGAGCTCATGACCCAGGTCAGATGATGCCAAGTTTCAT TTTATACATTCTCTGTTCTTCTTCTCTGCTCCTTAAGAGCGCAGGTCAGTAAGTGGGGTT GGAAACAGTGGACTCTTCCTTACTGGGGTATAGGAGTTGGCACGCTAAATATTCTGCAAA GCTTGCTCTTGCAGGACCAAGCATCTAAATAGTAAGGTCTAACCTCAGTCATCTGTTTCT GGAGGAAAATCCCAAAGCATGGCCTTTGGAGTGTGATTTAGCCCTCATTCTCAGATTCAG TGGTGAAGTTCAGAGGGGAGCCAATCCCTCTGAGCATCTCGAAGGTGGACAGAACAGTCA GCTCAGGAGGAAATCTCAAAACAACGCCCCTCCTCGGGAGTTCTCTTACCTTTGTCATTG TAGTTCCTAAAGGATGCACTCCTTTTCCTTTCTATTCTTTAATTCACAGGGTCCTTAAAC ATGGTTCCTCAGATTTCAATAATCTATACATTGGAGATCACAAAGAAATCTTAATACTGC CAATGAAAGGCTAAAAATTGTAAATGGCACTTTATTTTCAGTTTGACATTACTTTGCTGA TGATTCTTTTCATAATATATATGATTTGATTTACCTTATTTTTTACTTTGCCATCTGCTT TGCAATTAAATACACACACACACACACACACACACACACACATACACACACACACACGTT TTCTTTTTAAAGACAGGGCTCTGCTCTGTAACCCAAGCTGGAGTGCAGTGGCACAATTAT ATCTCACTGCAGCCTCCAACTTCTGGGTCAAACAATCCTGCCGTCTCAGCTTCCCAAGTA GCTGGGACTACAGGCATGTGCCAAAAAAAAAAAAATTAAATTAAATGAATGCAAGTCCAT TCTCAGTATGAAACACATACTGAAATAACTGCCTGAGAAATGGTACGTGGTAGATAAATG TGCAGCAGATGTGCTAATTGGCCTGGGTATAGAAATTTAGCTATTTGGTCTGGGTATACA ATTTTAGGTTGAGGACCATTGCACTCAGAGTTTAGATATGGTGGTTTGTTTTAGTGTCCA CTATTCATGATAAGAAGTCTCAGTCTCATCCTTAATAGGATTGACCTGTATTTTTATTTT ACTTTCATTTTCTTGGCATTTTCACAATGTTCTCCTTAGCCTTGGTGTTTTTAAATTCCA GGAATATATTGTCAGGAAAAGGACTGCTGATTTTCTTTCTTTCTTTCTCTCTCTCCCCTC CTCTCCTCTCCCCTCCCCTCCCCTCCCCTCCCTTCCTCTCTCTCTTTCTTTCTTTTTTCT TTTTCTTTCTCTTTTGTTGCATACTCTCTGGGCTTTTTAAATCTAAAGACTGACTTTCTG CTGTTGAGAACATTTCCTGTTTAATTTCTTTGAAAACTTTTCTTCTCTCTATTTTTTTTT TCTATTCTCTTATTCTGAAACTCATGTTGGTGAACCTTCTGAATCACTCCTGTAGGCTTC TAGCTTTCTGAAATTTTCCATTTGTCCCTTTATTCTACTTTCTGAGAGATTTCCTCAATG ATGTTTTCCAAACCTTCTGTTATTTCGTTTTCATTTCAGCAAATCATATTTTTAACTTCT AATAACTATTTCTTATCCTTGGAGTGATCTTTTCTATAGCATTTGATTCTTGGTTTATAG ATGTATCCCTCTCCCCCTGATCTTTTGAAAGAATACTAATTGGTGCAGTCAGAATTTTTA TGTCTGCCTGTCTGTTCCTTGAACTTCTATTCCATGAAATGTCTGGTATTTCTGGGGTTC TTCCCATTCCACCCCATAACTTTTCAGTTTTCTCTTTTGTGGTGAAGGTGTTTTTCAAAT ATCTGGTAATGGTTTATATCTATATGTATAAAAATGAGGAATGTCGGTTGAGCTGTACCC ACTTGCCGACTCGTCTGAATTTGTCAAGCTTATGCTATAGGTTGGGAATTCCACTTCTGT GTGATGGTAATTATTTTTTTCTTGGGCTTTTTGTTTCCTTTAGAATAGATCCTATCATCT GATTTTGCCCCTGGTGATGGGTATATTTGGCCTCTGAGAATTCTGCAGAATTTCAGTGAC TTCTCCAGTTTCTCTTATTGGCTGATGGTTTTCTCCTGCCTCTTTGTTGGCTTGGGGTTC ACACTTGCCTTCCTTAGCACACTTTTTAGTCTGTTCTCCTTTTATCTCAGAAAGAAGGAA AGAGAAACTAGGAGCTCCACATCCACCATCTTTGCTTGGAAGATTCCTGGTTTACACTTT TAATTACGTGATTGAATTGATGAAAATGGATGGACCTTGAAAACATCATGCTGATGGAAA GAAGTCAGACACAAAAGGCCATATGATGCTTAATTCCATTTACATGAAATATGCAGAACA GGCAAATCCACAGAGATAAAAAGTGATTGGTGGTTGTCACAAGCTAGGGAAGGGAGAAAG GGGAGATACTCCTTAATGAGTGCAGGGTCTCTTTTTGGGGTGATGAAATGTCCCAGGATT AGATAGAGGTGGTGGATGTGCAACATTGTGATGAATTGTGTTCTTTACAATGGCGAATTT TATGTCATGTGAAATTTACTGTGATAAATAAAAAGGAAATATGAAATTATTCCATTTTCA AAAGGCTACATAGTGTTTGATTCCATTTATAGGAAATATCCAAAATAGGAATGTAGAGAC AGAAAGCGGACTCATGGTTGCCAGAATGGGGAGTGACTGCGTAATGGGTACAGGGCCTCC TTTTGGAGTGGTGAGAATGTCCTCGGATTGCCTGGAGTTAGTGGTTGCACAACATTGCGC ATGGACTAAATGCGAGTCACTTGTGCACTTTAAAATGGTTTGTTTTATGTTATGTTAATT TCCCGTTAATTTTTTGAGAGTTTGCATGGAAAGGTGAAGCTCTAAGCAGGTCGTATGTTT AGGTGTGGGGATACCCATTATGCTGCTTAGAAATATGTTCACACTTAGGGCTCAGCACTG GGGGTTCTACTTGGTAATTCTTTCTGCTTCCACACTCTTTCAAGATATGGGTCAGAGAAA CCCTGGTGAGGACGGGGTAGGGGATTGGATCTCTGGCTCTGTTTTGGGCATTGTGTGATT TTCGAGGTCTGTGGGTGAAGCTCACACAGTACCTTTACCTTGGCCAGCTCTGGGCTTTGC AGATGCCAGTCCCGAATGCCTGCTTCCTCTCCCAACTCTGTCCTCTGCTTAGAGACAAAA GAAGCCTTACAGACAGCTGAATGGGTCCATGACAGCTACGCCTGTTCTTGGGAAGTAATT TTGATCAGAGCTCAGGCCTTTGGAAATGTCTAAAGAAGTAGTAATCACCATTATTATCAT TTTAAAGCTAGTAACTAAGAAAACTATAGATAGATTATAGATAATGGTAGAGATAATTTA TAATCTATAGACTGTAGGTAGATAGGTAGATGATTGAAAGATTGATAGATATAAATAAGT AGATACATAGAGGACATATATATGATAGGTAGATGGTAGGTATAGATAGATGGATGGCTA ATAGAAAGATGATAGGTAGAGAGATGATGGAGATAGATGGATGATAGATGATAGATATAT AGATGATAGATAAATAGATATAGATGATATATGATAAATAGATGATAGAGATACATGGAT TAGATAGCTAGATAGATAATAGAGATACATGATAGTAAGATAGATAATAAATAATAGATG TGAAGAGGATTGGTAGATGATAGGTGGATAGATGGATGGATAGATGATAGGTAGATGGAT AGATAGATGATGGATGGATGGATAGATAGATATATGATAGATAGATGAATAGATGATATA GATAGATAGATAGAAGGATGGATAGATAGATGATAAAGATAGATCGATTATAGTAAGATA GATAATAGATGTACAGAGAATTGGTAGATGATGGATGGATGGATGAATAGATGGATAGAT AGATGATAGATGGATGGATGTATAGATGATAGATAGGGATAGATAGACAATGGATGGATG GATATATGACAGATAGATGGATAGATGGATGGATGGATAGATAGAGATAGATGATAGTAA GATAGATAATAAATAATAGATGTGCAGAGAATTGGTAGATCATAGGTAGATGGATGGATG AATGGATGGATAGATAGATGATAGATAGGTAGATGGATAATATAGATATTATCCAATGAT AGATAGATGATGGATGGATGGATAGATAGATGATAGATAAATAGATGAATGGATGGATGG ACGGATGGATGGATGGATGGATGATGGGTAGATGGATAGATATGGACTGATGAAAGGTAT CTTTTGTTCTACAGAATTAAGTTGTAAAGTTTGCTGTCTGTAATTCTCACTCCCAATGGA GATGTCAGGAATTCTCGTTCTTTCTTCGTTCAAGGGTGGGGAGGAGGAGTCTACAGGAGC AGCTGTAACAGGCACATTTTGGAATTTACCCCATTGGAATGTAAAGGTCAAGGAGGCAGC CCTGTACCACACGTCTGGGACGCTTGTGTTTGTTATATTTAGTGCGAATTGTGGGTTGGC TTTGCTTGGAGTGCTGCTTCCGGGAAAGGCGCTGTGGTCGCCTACATGCTGAGCATTTTA ATTTCCATAGACAGTACACTGGGCTGCACACTGCATGGGACTTCTCGGCATTGCTGGCTG CCCTCCTGACTGTTGTCTTTCTCCTGGCAACAGGGGCTTGGGTGCCCAAGAATCAAGTGG TTTAAAAGTCATTACCAAAGTTCACATCAGTCTTGTGCACAGAGAATTAAAACTGCTGTA AATTATATCTGCTGTGAGAGCTCCTTCCTCTCATACTGAGGCATTAGGAAATTGAATCCA TTCTACCTAATGAAACAATGTACTTTTCCTTATGTTGTCTCTACCGCCTCATACATCCCT GAGTTGAACTTGAAGTCTTTGTAAGAAATGGTCTGTCCAGAATTTAAATAACATGTTTGG CTGCTTCTTTATGGAGCACGATTCTTTTCTTTCCTTTCTTTCTTTTTTCTTTTTTCTTTT TTTCAGAGACAGGGACTCACTCTGTTGCCCAGGCTGGAGTTCAGTAGTGTGATCATGGCT CTTTGCAGCCTTGACCTCCTGTGCTCAAGCGATCCGCCTGCCTCAGCCTCTCAAGTAGCT AGGACTACGGGCATGCACCACCTCGCCTGGCTAATTTTTTTTTTTTTCCAGTACAGATGA GGTCTTGCTGTGTTTCCCAGGCTGGTTTCAAACTCCTGGGCTCAAATGATCCCCCTTCTT CGACCCTAGCACTGGGATTACAGGCATGAGCCACTGCACCTAGCCCAAAGCACAGTTCTT TTGAGTGAGTTGGGTTACATCTTTGCTGTAACTCAGGTCATCAAGCCATCACTTCCACTT TTTGCCTTTTGTTTTCACCTAAGATCTAAACACTTTGGGTGAGTTTTCAAGAGTCAAACA CAACATAAAATAAGGGATAGTAGCTATGAGTTTCCATGGCATTGCAGCATCAGGAAATGG GCATAGCAGTTGGGTTGACTTTGTCCCTTGTTTAAGGTTCCTTCATACTCCTCCTGTGTT TTGTTTTGTTTAGAATGAAAGGAAGCATGTATGCGAATTAGAATACTGAATATTCACTGC AAGTCGTGATTTTTTTTTTTTTTTTGAGACAGGGTCTCACTCTGTCATCCAGGCTGGAGT ACAGTGGTGCAATCACGGCTCACTGCAGCCTCAAACTCCCAGGCTCAAGTATCCTCCCAC CTCAGCCTCTCCGAGTAGCTGTAACTGCAGGCCTGCCACCACGCCCAGCTAATTTTTGTA TTTTTCGTAGAGACAGAGTTTCACCATGGTGCCCAGGCTGGTCTCGAACTCCTGAGGTCA AGCAATTCACCCACCTCAGCCTCCCAAAGTGCTGGAATGACAGGTGTGAACCATCACGTC TGGCCCAAGCCATGAATCTTGGGAGAGGAGAGGAGGTGACTATGGCCCCGTCACCCCTGC TGTCCCTCAGGAGTGTAACTCTGGTGTTTCTGTTGATTTTCACAGTGACTGATCAGGCTT TTGTCACACTAGCCACCAATGACATCTACTGCCAGGGCGCCCTGGTCCTGGGGCAGTCAC TGAGGAGACACAGGCTGACGAGGAAGCTGGTGGTGTTGATCACTCCTCAGGTGTCCAGCC TGCTCAGGTAAGGCTCAGAGATGCGGCTTGTGCCCAGCTGGGTCCTATAGAAGGAGGGTC ACCTCTCCCCTAAGAGGTCCTAGGAGTTATTCTGACGACTGACTGCCCTTCTTCATAGGC CTGGATGGCCGGCAGTCATGATGGGCATCTGACGTTTGTAAGGAACCTTCGAATCATGTG AAAATATAGGCGTGTGATCGGCTTCACAATACTTTAAAAAACAATACTGGGTTTGGTTAC AGTTCATTCTCCCAACCATGGAAACTGAAAATTCAATTCTTTTTTGTTTGTTTGTTTTTT GAGACAGGGTCTCGCTCTGTCGCCCAGGCTGGAGTACAGTGGTACCATCTTGGCTCACCG CAACCTCTCCCTCCCAGGCTCAAGCGATCTTCCCTCCTCAGCCTTCTAAGTAGCTGGGAC CACAAGTATGTGCCCCCATGCTCGGCTATTTTTATTTTTATGTTTTGTATTTTTGGTAGA GACAGGGTTTCGCCACGTTGCCTAGGCTGATCTTGAACTCCTGGACTCACTCAGTCCACC CAGGTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAACCATGGCACCCAGCCAAGGAG TCTTTTCTTATAATTTCCTTTTATAATTCTCTTTGTCTTTAATTCTCAAATAAAGCAAAT ACATAAATAAATGCGTCTAATGAATAAAGCATAAGGCTTCTCTTAAATGTCATACATTAT GTAAGCAATAATCTTTTTCTTTCATCAACCATGGACCACTTAAAAAAATTGATTTTATAC GAATGGGACGAGGAGGCATTTAATATGGTAGATGTAGCAGGAATTGAATGTCATATTCTT TGACAATGAAATAATAAATCCAGACATTAATAGCTAAACTAAAAAGAGAACAAATAAAAA ACCAACCAGTGTGTCCTCAGACGTTTGAAACTGGAAGTTTTAAATGAAATAACTCAATCC GGGTACAAATGAAAGCTTGAATTATGTACTATTTCAGAAAATCACTGCAATGTGAGTGCT ACCTATACAAAGCAAAGACAGCAACTACAGTGGTACAAGACAGAAAATTTAAATCAGTGA AGAAATTATCCAGTTCAAATATATATGTATATACACACACGTATGCATATATATGTGTAT ATGCACGCGTGTGCGTATATATGTGTATACGCACACGCATGCGTATATATGTGTATACGC ACACGCATGCGTATATGTGTATACGCACACGCATGCGTATATGTGTATACGCACACGCAT GCGTATATGTGTATACGCACACGCATGCGTATATGTGTATACGCACACGCATGCGTATAT GTGTATACGCACACGCATGCGTATATGTGTATACGCACACGCATGCGTATATGTGTATAC GCACACGCATGCGTATATGTGTATACGCACACGTATGTGTATATGTACACGTATGCATAT ATATATACATGTATGTGTATATATTTATATATACGTATGTGTATATGTACATGTATGTGT ATATATTTATATGTACAGGTATGCGTATATACACATGTATGTGTTTATATTTATATACAT GTATGTATACCTGTATGTATATATGTTCAACTATATATTTTTATATACATGTATGTATAT ATTTATATATACATGTATTATATATGTTCAAATATATTTATATACACATGTGTATGTATA TTTATATACACATGTGTATGTATATATACACGTGTGTATGTATATTTATATACACGTGTG TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG TATACACATGTGTATATATACACATGTGTATGTACATATATTTATATACGCATGTGTATT TACATACATTTATATACGCATGTGTATGTACATACATTTATATATGCATGTGTATGTACA TACATTTATTTATGCATGTGTATGTACATATATTTATGCATGTGTACGTATATTTATTTA TGCATGTGTATGTATATATATGCATGTGTATGTATATATATACATGTGTATGTGTATATA TATGTTCAAATGTATATGTATATACATATAAAATATATATATTTGAACTGGATTTCACTG ATTTAAATTTAAAATATATATACACACATATTTGAACTGGATAATTTCAAATATATATAT TTCATATATATATTTGACTTGGATAATTTCTTCACTGATTTAAATTTAAAAAAATATATA CATATATGTATATATATACATATATATACACACACACATATATATACACATATATATATA TATATATATTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCGT CCAAGCTGGAGTGCCATGGCGCGATCTTGGCTCAGTGCAACCTCCATCTCCTGGGTTCCA GTGATTCTCCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCATCCAACATCACGCCC GGCTAATTTTTGTATTTTTAGTAAAGACAAGGTTTCACCACTTTGCCCAGGCTGGTCTCG AACGCCTGACCTCAAGTGATCTGCCCGCCTCCGCCTCCCAAAGTGCCAAAGTGCTGGGAT TACAGGTGTGACTCACCGTGCCCAGCCCCAAATATTTTTAAAATAATAATATTAAAAAAG CAAACAGCAGTAAAAAATTCATAAAGATAAAATGACAAAACTAATAATTGGGAACAAGAA ACAAATTCAAGGATTAGGTTAACAAATCTTCAGGGAGGCCAAGGTGGGAGGATTGCATGA GGCCAGGAGTTTGACAAGACAGGCTGGGTGACATAGCAAGACCCTATCTCTACAAAAAAT AAAAAGAGTTAGCCAGGTGTGGTGGTGCGCACCTATAGTCCCAGCTAGTCAGGAGGCTGA GATGGGAGGATTGTTTGAGCCCAGAGGTTCGAGGCTGTAGTGAGTTATGATCACACCACT GCACTCCAGACTGGGCAACAGAGTGAGCTCCTCTCTCTAAAAATAAAAATAACAAATAAA AATGAATCTTTTATTCGAGAAAACATAAATGTACAAAATTGAAATTAGAAAGAAGTCATT TGGAGGCAGTTTTAAAAGCAAATAGTATATAGAACCCTTTACAGTAGTGACACTGGGAGT ATTGAAGAAGTGCTTGATCCTTCTAGGGAAATCGGTGAGATGTTGGTTGTTGTCATCAGA AGAAATAGAAACCTTTTGTTTGACAATAACTATGAGAAAAACTGAAAATGTTACCAAAGG CTTATCTTGTAGAAAGGCCCTGGTTTGGGCAATTTTAAGGGAAGTTCTGTTAAATTGCTC ATGATGAATTAATTTCCCTGCTGCATAAACTGTCACAGAGCCTAGCAAAAGATGAATATG TTCACTTATTTTAAGAAACTGTTATAATCTTGACACCCAAACTTGATTTACAGGTTTGAT TGTGTTTACATTTGGATTGAGAAAGCCCTCAAATACAGGATGTTAATAAGGCAACTCTAG CCCTGTAGTAAAGAAATAAATAGTGCTTACACTAAGAAAGCAAAGATAGGTTATTATTTT AAAACCTATTAATATCATTCAACACATTAATATGTTAGAGAAAGTCAATGATAAGATCCT TTTAAAATAAAAACTAAACATATAACAAAAAGAATTCCAGGCCGGCCACGGTGGCTCATG CCTGTAATCCCAACACTTTGGGAGGCTGAAGCAGGTGGATCACTTGAGGTCAGGAGTTCG AGACCAGCCTGGCCAACATGGTGAACCCTGTCTCTACTAAAAGTACAAAAAAAAAAAAAA AAAAAAATTAGCTGGGTGTGGTGGCAGGCACCTGTAATCCCAGCTACTCGGTGAGGCTGA GGCAGGAGAATCACTTGAGCTCGGGAGGTTAAGGTTGCAATGAGCCGAGATGGCACCACT GTGCTCCAGCCTGGGTGACAGAGCAGGACTCTGTCAAAATAAATAAATAAATAAATAAAT AAATAAATAAATAAATAAATAAAAATCCACATAGATTATAAATATAGAGGTAAACATTTA AAACATAGAGAAATCTTAGAAGAAAGTAGATGAAAGTTTCTCAGCACTGCTGCTATCTGG GACTGGAGGGTTCCATGTGGTGGGGTGTCCTGTGTACTGCAGGGTGTTGAGCAGCGTCCC TGGGCTCCGCCCACCAGATGCCGGCAGGAGTTGGCAGTTGTGACAACTAAAAATATCTCC ACATGTTGATGAAGGTGGATGTTTTGTTCATCTGAAAGCTGGAAATGCTGGTGTAAATTA AACAAGATGGAAGAGGACACCAGAACTGCTGTGTGTCAGAGATATTATGTGTTAAAGATA AAACAAACTGAGGGCCACATTTAAAATATTATAATGGAGAGGTTCTTATTGTCCATCACG TACAAAGAACTCTGAAAACACTTTAGGGGTTTGCACGGGCTCGTCTCTAGCACGCCAGAA GCAAAGATAGACAGACAAATACAAAAATAGGTATTAAACACGAGCAACTGGCTGGGTGTG GTACCTCACGCCTGTAATCCCAGCACTTTGGGAGACTGAGGTGGACGGATCACTTGAGGT CAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTTTACTAAAAATACAAA AAACATTAACCAGGCGTGGTGGCGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGA GAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCCAGATCGCGCCACCTGCACTC CAGCCTGGTGACAGAGCGAGACTCTGTCAAAAAAGAAGGGAAAAAAAAAAAACCTGACTA TATTAAGGTCCAAAAATGCACCAGTGAGTGGAAAGGTACACATAGCACATCCAGCAGGTT CCGTGTTTTATTTTAAAAGCCGGCGGGGGCGACGGGGTAGAAAAATGCTGTTAAAGAGTG TAATTGAGTTGCTTGTAACACAAAGGATAAATGCTTGAGGGGATGGATACTGCATTTTCC ATCATGTGATTATTACTTATTCCTGCCTGTGTCAAAGTAGACTTAAGGTTCACTCAAGAG GAACTTTAAAATATTCAGAAACAACATGGCAGAAATCGTGGGAAGGTTCAGTGTTGCAAG TCGGGTTGAGGTTTTGTGGGACCTTTTATTATATGTTTCGTAGTCATGGGGAGAATTGAG GGATGGCGCTCTGCGGTGGTCAGGGCAGTGGAAGACGAGCAGTGAGCAATGACCGTAAAT GACCAGGGGTGTGGGTGGTGGGAGATCGCCCCTCCCCCAGGCTGTGTGGTACAAGCGTGT TATGGAGTGATCTTGCAGGGAAACCTGCTTTAAACTAATTGTATTCATGAAACATAATTC TGCTTCCAGGAGTTTATTTTAGGGAAATGAGCAGAGCTGAACAAAAAGATGTAAGGACAT AAATGGCAGTGCCATTTGTAGTGAGGTGGAGTGCTGTTTCTCTTGCCCTCCCCCCAGCCC GGATCTTTACGCAACTGTGGTGAAGATGCCATAAATTCCATAAATAACTGGGCCAAAAGC AGAGGGAGATTTGCTGAAGGAAGGGTACTTTTTCAGAGAAATAGTTACCTTAAATACAGA GCAGTGAAATCTTACAAATAAATGTCGAGTCCAAGAGAAATGCTAAGAGATAGAAAAGGT CCGAGAGCTTCAATATCTGTCAAATAGGAGAGAAAGAAAAAGAAAGAAAGAAAGAAGTAA CTCCTATTATATTTCAGCTCTGAGACAAAGTTTAGATTGAAAGTGTTCCAGATATTGAGC AGAGTGGATGAAGAAAGCTCAAATGTAGACACCAAGTGGTAAAATTTCAGAGCAGCAAAA ATGAAGAAAAATCCTAAATGCCTTTCTGTATCAATCTGGTTGTGACAATTGATGTCTCAA AATTCTGGTGCAAGATAACTTTGAAATGAAAGTTCTGTATTCAGCTTTAGTACCGTAATT TGAAAGCAAAACAAAGACTTTTCAAATTTGCAAACGTTAAAAATGTTATCCCTCAAAGAT CTTTGAGGAAAAAGTTAGTTGATTGACTCCTGCAAAATGGAATGTAATCCAAGAAAGGCG AGAGTAGCCAAGCACAGTGGCTCATGCCTGTAACCACAGCATTTTGGGAGGCTGAAGTGG GAGGATCGCTTGAGTTCAGGAGTTCAAGACCAGCCTGGACAACATAGTGGGGTCTCATCT CTACTAAAAAATTTTTAAAAATTGCTGAGTGCAGTGGCACATGCCTGTAGTCCCAGTTAC TCAGGAGGCTGAGGCGGGAGGATCACTGGAGCCTAGGACATTGAAGCTGCAGTGAGCTAT GATTACACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTCAAAATAATAAT AATAATGATAATGATAATGATAATAATAAATAGAAGAGAGCACACAGGAAGCAGTGCTGA ATAAATAAATGTATAAAACAGAGTTAAGTCTGAATGTGTTAGTGCACAGTTACGAAAATA ATCTGGAATTAACATTTCACATGGGAGGTAATTGAAAGAGCAGAGAAGAAAGAATGAGCA TATGTTCATGTTTTTGTTTCGTCTGGGAAGAAGACATAGGTAATGACTATATTTGATAGA AAATATAAGCTTAAATACGTGTGCTGACAGTTGAAAGGTGGTTACCACCAGAAAACTAGA AAAGATGTGTACAAGTTTCAGAGCCTTAATGGGAAATGCGTGGATTGAAGAAAACCTGAT TCATGCAATCAGAGGTGGGTGGGAAAGAATTACACTGATGTCAGGCCTCTGAGCCCAAGC TAAGCCGTCATATCCCCTGTGACCTGCATGTACACATCCAGATGGCCGGTTCCTGCCTTA ACTGATGACATTCCACCACAAAAGAAGTGAAAATGGCCTGTTCCTGCCTTAACTAATGAC ATTATCTTGTGAAATTCCTTCTCCTGGCTCATCCTGGCTCAAAAGCTCCCCTACTGAGCA CCTTTCGACCCCCACTCCTGCCCACCAGAGAACAACCCCCCTTTGACTGTAATTTTCCTT GACCTACCCAAATCTTATAAAACGGCCCCACCCCTATCTCCCTTCGCTGACTCTCTTTTC GGACTCAGCCCACCTGCACCTAGGTGAAATAAACAGCCTTGTTGCTCACACAAAGCCTGT TTGGTGGTCTCTTCACACGGACGGGAGTGAAAACTGAAGAAATAGAAAATCTGATATATG TAAAAAAGGGAAAATAATATAAAATGAAACTGCAGGACTCAATCCAAATATAACCGTGAT CATAATAAACATGAATAGATTAAAATTCCTTTTTAAAAAGATAGGCTTTCTGAATGGGAA AATAAACATAAAATCCGGACATACAGTAGTGTAGGAGGCAGCTTAATTAAAAACAAACAA AATGTTGAAAATAAATGGATGCATTTGATATGATTCTGTTCCACTATCCAATCTAAGTAA TGGTCAATTGTTTTATAGATTGTTCTTCAGTTGTTTGTTGTTGTTGTTGTTGTTTTGAGA CAGAGCCTCGCTCTGTCGCCCAGGCCGGAGTGCAGTGGCACGATCTCAGCTCATTGCAAC CTCTGCCTCCCAGGTTCAAGCAATTCTCATGCCTCAGCCTCCAGAGTAGCTGGGATTAGT TTCCCGCCACCGCACCCGGCTAGTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGT TGGCCAGGCTGGTCTCGAACTCCTGATGTCAGGTGATCCACCTGCCTAGGCCTCCCAAGG TGCTGGAATTACAGGCATGAGCCCCTGTGCCCAGCCTTCAGTTTGGTTTTGTCCAGTGTT TTCTCATGATTAGACTGAGGTTATGCATTTTTGGCAAAAAAATCATCAGAATTGATGTAA GTTTTCAGTGTGTCATGCTATGGAGTGCATGATGTCTGTATGTCCTGACCTGGTGATGTT AAATTTCATCACCTGGATTAAGTGGTGTCTGTTGGAATTCTCCACTGTGAAATTATTATG TTTTTCTTTTAGTAATGGAAAATATCTTGGCATAGACATTATACAAACAGCCTGTTTCTT CTCTAAAAATCAGTGAGTCTTGTCTGCAACAGTTGTTACTATAGTGTTTGCCTAATCGTG GTTTTCTACTTCCCTCATTCCTTCTATTTCAATTACTTGGAATTATCTTCTAAATTAAAC CTGCCCTTTCTTTCTCACATATTTGTTTATTCAATAGTTATATTAGGTCAGGCGTGGTGG CTCATGCCTGTAATCCCAGCACTTTGTGAGACTGAGGCAGGCAGATTGCTTGAGCCCAGA AGTTTGAGACAAGCTTCATAAACATTGTGAAACCCCATTTCTACCAAAAAATACAAAAAA TTAGCCGGGCATGGTGGCATGCACTTGTAGTCCCAGTTACTTGGGAGGCTGAGGCAGGCG GACCACTTGAGCCCAGGAGTTCGAGGCTGCAATGAGCTATGATTGCACCACTGAACTCTA GCCTGGGTGACAGAGTGAGACCCTGTATCAAAAAGAAAACTTATATTAGTGTAGGCTCAT GAATATTTATTTCATATTTTGGGCTTGTTGTTTTTTGTTATTGATTACATTATTTCAGCT TTGGCAATTGGGTGCTTCCCCTAGCTGGCCCCCTGTATTCTTTCAATATGCCCCCATCCT TTTCTAGCACTTGCTTAATTTTTCTGTCATCCCAATATGTTCCAGACTATGATGAAGTGG GATTTAAGCAAAAATAAATAAATAAATGGAACAGAGCAAATTTCACTTTGATAAAATGGA CAGTCTTTCAAGCTTCGAGTCTCAAACTTGTATGCAACTAACAATGTAAGCTTTGAATAC AGAAAGTAAAAATTGATAGAGATTGTTATGGACATCTGTTAGTTTCTACCAGCTCAGCAT TTACATTTCTCTGCCTCTGCAGCTTACAGAGGGAAACTGTCTTCCTAAGAGCTGGCCCAA GTGCATGCATCTTAAGACAGTTCTGTTCAATTTGTCACATTTTTCAAGTATGCATGCATT TCTTTTTCATAATATTAATATTTATTACTATATATGAATACTAGATTGAAAGCCCAAGCA TTCAGTTTACACACAGAAATTATGCAATTATATATCGCTTCACAAAGGCAGTGAACACAT TACATTCTACAAAATCTACTTCACAGAAATTTAAAAATTCTAAATATCAAAAGGTACAGC TGAAGAAACAGGTATAAATTTGGCAGCCAGTAATTTTGACAGGGAAGTTGCAGCTTGCAT GACTTTATTTTTTTGTTTGTTTTTTGAGACAGAGTCCCACTCTGTCGCCCAGGCTGGAGG GCAGTGGTGCCATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTG CCTCAGCCTCTTGAGTAGCAGGAATTACAGGCGCCCACCAGCACGCCTGGCTAATTTAAA TTTTTTGTTTGTTTGTTTTTGTTTTTTTGCTTGTTTGTTTTGAGATAGAGTCTCGCTCTG TTGCCCAGGTTGGAGTGCAGTGGTGCGATCTCAGGTCAGTGCAATCTCCGCCTCCCGGGT TCAAGCGATTCTCCTGCTTCGGCCTCCTGAGTAGCTGGGACTACAGGCGCCACCACACCT GGCTAATTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCATGCTGGCCAGGCTGATCTTG AACTCCTGACCTCAAGTGATCCGGCTGCCTCGGCCTCCCAAAGTGCTGGGATTGCAGGCA TAAGCCACCGCGCCAGGCCTTGCATGACTTTAAATATATGAATATGAAAATATTGAACTT AGAGTAATCATTGTGCTTTGTGTTGATTGAAAAATATAACAATGGCTATCAAAGAAGCAT GTTCAAAGATGCTTAATTCACTTCAAAATGTCATACAAATTGTGGTGGTTTCTATGCACC TCTAAAGCTTCCGTCATTTAGCTCAGGTACATTACTAAAGTAATATATTAATTCTACCGG TACAGTGGGGTTTCACACCATTGGCATTTGCATTCAAGCATGCAGAGGCTTTTGGGCACA AGTGGACGGTGTGCACAGCTCTAAGCCATCCGTGGAAATGTGCTCTGAACATGGAGACCG CAGTGAGGGCTGTGGGGATTCTCTTTGCATTCCACGTTTGTGAGCAGCAAAACAGCACCC TCTTGAAGGAGGAGGTGGTTCTGTGCTGAATATTCACCCGCTGTCCCACTATTTGGCACA TGTCTGTTCCAGGGTCATCCTCTCGAAGGTGTTCGATGAAGTCATTGAAGTGAATCTAAT CGATAGTGCCGACTACATCCACCTGGCCTTTCTGAAGAGACCTGAGCTCGGGCTCACCCT CACCAAGCTTCACTGTTGGACTCTCACTCACTACAGCAAGTGTGTCTTCCTGGATGCAGA CACTCTGGTGAGTGAAGACTCTCTGCTTGATAGGAAACCCTCCAAGACCACATCTCTATC CTTAAGCAGGCTGTCAACTTTTTTTTGTGTGTGTGTGACACAGTCGCTCTGTCACCCAAG CTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCTGAGTTCAAGTGAT TCTCCCACCTCAGCCTCCCGAGTGGCTGCTATTACAGGCACCCGCCTTCATGCCCGGTTA ATTTTTGTATTTCTGTACAGACTGGGTTTCGCCATGCTGGCCGGGCTGTCACCTCTTACT GGTAGATTCCTGTGAGGCCATGTGCATTTCTATTTCTAACACAGATGTTCAGTCTATTAT AATCAGGCATAACATACCCCCGAGCACTGTGCTAGACCCTGCTGAAGAGAACAGGGGATT GGAAGACATGTTCCTACCCCAGGAATGAATTATAACCACAGTATTTTACACGCACAAAAT AGAATCATGAGGGAAAAAACTTGTGACTGGGCACAGTGGCTCATGCCTGTAATCTCAGCA CTTTGGGAGCTTGAGATGGGTGGATCACTTGAGGCCAGGAGTTTGAGACCAGCCTGGCCA ACACGGTGAAACCGTTTTTACTAAAAATACAAAAATTAGCCAGGCATGGTAACAGGTGCC TGTAATCCCAGCTACTCAAGAGGCTGAGGTGGGGGGATCGCTTGAACCCGGGAGGCGGAG GCCGCAGTGAGCCGAGACTGAAGCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTG TCTCAAAAACAGAAGCATTGGTAAAAGAAGCATTGCGGCGGGTTCTGCGTGTTTTGCTTC ACCAGGTGCTGTCCAATGTCGATGAGCTGTTTGACAGGGGAGAGTTTTCTGCGGCCCCGG ACCCCGGATGGCCGGATTGCTTCAATAGCGGGGTGTTTGTCTTCCAGCCTTCTCTCCACA CGCATAAACTCCTGCTACAGCACGCCATGGAACACGGCAGCTTTGACGGTAAGTCAGGGC AGCCCGGACGCTTAGGGTCTCTGTTGCACACACTCAACTCTGCAGATGTAACACGAAGTC AGCCGTTGACCATACAGTCACACCTCGCTCAGCGACAGGGATGCGGTCTGAGAAATGTGT TGTTAAGTGATTTTGTCATTGTATGAACGTCCCAGAGTGTATCTGCACACACCTGGATGA TGTAGCCTACTGTATACCTAGGCTGGAGGGTACAGCCTATTCCTTCTAGGCTACAAACCC ATATAGCATGGGAGTGCACTGAATGTTGTAGGCAACTGTAACATAATGGGAGGTATCTGT GTTCTAAACATACCTAAACATCACAAAGGTCCAGTGAAAATACAGTATAAAATCTTATGG GACCACCGTCAGATGTATGGTCTGTCTTTGACCGAAGCACTTTTATGTGTTGCATGACTG TACTTGGCATTGAACATGGGCTGGCCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGG GAGGCCAGGGCGGACAGATTGCTTGAGGCGAGGAGTTCAAGACCGGGGTGGGCAGATGGC TTGAGACCAGGAGTTCAAGACCAGCCTAGGCAACGTGGCAAGACCCCATCTCTACAAAAA ATACAAAAATAAGCTGGATGTGATGCTGGCACCTGTAGTCCCCAAGCCCTGGGAGGCTGA GTTGGGAGCAGCAGCTGAGCTCAGGAGCTCAAGCCTACAGTGAGCTATGATTGCACCACT GCACTCCAGTCAGGTTGACAGAGTGAGACCCTGTCTCAGAGAAAAAGAAAAGAGCATGGC TGTGTTCCAATAAAACTTTATTTATAAAAACATGCACAGTGTGTAGTTGCTTGACCCATG GTAGAATATAGGGAGAATTAAAAGGAGGCAACCTGAAGCCGAGTATTTGTTGAAATGGGC GTCAGTAGAGAGGAAATGTGCTGGAATTTTTGTAAAGTAAAAGAAAATACTGGAGCAGTG AAGAATTGCCTCTAGGTAAAGGGGAAGTTAATGAAACTGGCAAAAATGATGGGAAAAGCA TTGTCACTACCAGGGAGAATTCATTAGGGGACCAGTGGAATGCTTTGGACTCCATATGCA ATTTTAGCATTCATTCTGGGGACTCCTGGTGGAGAATTTTGGAGGGAATATGCACTTATT TTTATCAATGGCTTGGGTTATCAGTCTTTTCTGAGAACCAAGAGAATGTGTGCAGCTGGC AGACAGAAGAAATGGAATTAGTAACCCTGAAGGCAAGTGTTTATGTTGAGAGCTTCAGGC ACATCTCGCATTCTTGGAGTGAACCAAGCCATACTTTGCTAACCTGCTTTTGTGTTTGCT CATTATGTAGGGGCAGACCAAGGCTTACTGAATAGTTTCTTCAGGAACTGGTCGACCACA GACATCCACAAGCACCTGCCGTTCATCTATAACTTGAGTAGTAACACGATGTACACTTAC AGCCCTGCCTTCAAGCAGTAAGTTCTCCACCCTGGCGAATCCTGCCAGATCTGCCACTAC CGATCCACCTTCCCTCCTGGAAGACATACCAGCTGTCGGCATATTTAAAAACTCTATCTA TCTATCTATCATCTATCTATCTATGTATCTATCTATCTATCTATCTATCTATCTATCTAT CATCTATCTATCATCTATCTATCTATCACCTCTATCTAGGTAGATCTAAATATCTATTTA TCTGTATAGATAGATACCTATGTCTATGTGTCTGTGTATCTAGATCTCTATGTCTATCTA TATAGATATATATCTGTCTATATAGTTATCTACCTATATAGGCCTAGACATCTGTTTATC TATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCCATATCTATCTATTTA GATCTGGATATCTATCTGTATACATAGATCTATATATCTATATCTATATATGTATCTATA TCTAGATCTAGATATCTATATACATTGATCTATCTAATCTCTATATCTATGTAGATATTT ATCTATCTATCTAGACCTAGATGTCTATCTATCTAGACCTAGATATCTATCTATCTAGAC CTAGATATCTGTCTATCTGTCTAATCTATCATCTATCATATGTATCTATTCAGATAGATC TGGATATCTATCTATAAACATCTTATCTATCTATCTATCTAGATCTACATCACTATATAG ATACCTATATCTATCTATCTAGAACTAGATATCTATGTATCTAGATATCCATCTAGATTT AGATCTTCATCCATATAGATATCTATATCTATCTATCTAGATCCAGATATCTATCTATAT ACATAGATCTATATATCTATATCTGTATATCTATCTAGATCTATCTAGATATCTATGTAT ATACATGGATCTATATATCTCTCTATGTATCTAGATCTAGATCTCTCTCTATATAGATCT ATGTATCTAGATCTAGATCTCTATATAGGCATCTATCCATCTATGTAGATCTAGACATCT ATCTATATATTAATACATAGATGTATCTATCTATATACGTCTTTATATATGTATATACAC ACACAGAAACACACACACACATCTCGTTTCCTGCTTGCTTGTTGCTGTAAATGATAGCTA GCCAAGGCTCTACGACAATGATCCCCAAAGTGTGGCCCAAGGAACCCTGACCCCACAACT CTTTCAAGTGTCTTCAAAGTCATAACTACTTTAAAAAAAGAATTTGAAGATGTGATTTTT TTCCCTTTTTGCTGCCATTTTCTCATGCATCTATGCTGAGAGTTTACAGACACTACATGG CATGTGATAAGGTAATACCCTGAACACAGATGGAGCTAGGAAGAACCAGCTGTCGCCTCT TGGGAAAATGGATGGCACTCTTCTCACAATGATTTTTTTTAATATAGAAATTTTTTTAAT GAAAAATTATGAAATTTATGTTACTGCATAATGGTTTGATTTTTTTTAAAGGGATTGATA AATATGCTTTCTAATTTCTCAGTTTTAATATCGATTATTCTAAATATGGAGAGAGAGAAT CCACAGGGACATGGCCGAGCACAGTGGCTCACGCCTGTCATTCCAGCCCTTTGGGGGCCG AGGTGGGCGGATCACTTGAGCTCAGGAGTTTGAGACCAGCCTGCGCAACATGATGAAACC CTGTCTCTACGAAAAAATAAAACAAAACATTAGCCGAATGTGGTGTCGCACACCGCTAGT CTCAGCTACTCGGGAGGCTGCGGAGGGAGGCTCACTTGAACCTGGGAAGTGGAGTTTGCA GTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGTAACAGAGCAAGCCTCAGCTCAGG AGAAAAAAAAAAGAAAGAATCCACACGGACAAAGCTCTTTGGGTTCCTAAAAGGGTCAAG GGTGAGGGGACCAGAGGCTGTGAAATTCACTGCTCCAGAAGATATGGCTATAAATGAAAA TAGAGAATCTGAGAATCACCTTGGGAATGAATAATTCTAGAGTCTGCATTCTCTACAGAG GACACGGTGTCCCTAAGGAAGAGAAATTGATTCTTGGGAGTGAAATCTTGTTATTTTTTA CTGTATAATCACAGATGTAATGTACAGAACATAGATATGTCATGTGACTTTTGTGTTCAT ATTTCATGAGGAGGTGATCCACGAAAAAAAAGTTTAAAAAGGCTCCTGGAGGATGGTGAT GATGAACAACAAAAAAGTTGGCAAGGGGAACATTTAGAATCCTGTAAAAGAGAAAAAAAG CCAATTGCCTTGCCGCTTGCATTAGCCACTGTAAAAGCTATTTTTTTTTGCCCCTGTCGT TTTAAGGATATGATGATTTGGGCTGCTGTACTTCACGTTTTTACAAAACTGATTTATTTT TCCCGTTTTGGGAAAAAATGTCAATGGATTACGATTATGTTTTTTGATATATAGAAAATA AAATAACTGCAAAAACTGTGATTTAAAAAATATATCTTTATGCAAAATAACTGCAAATGA AACTACTACTACTATGCTGATAGCAGTGGAGTAGTATTATTGATGATATATTGATTACTA TCTTGATAGTAGTGGTATGCTAGTATTGCTCAGATATTGATTACTGCATTGATAGTACTA GTATATTATTATTGATTATATATTGATTACTATAGTAGTGATAGTATTTTGTTATTATTG ATCACACATTGATTACTGAATTGATAGTAGTAGTATGTTACTATTGGTTATATATTGATT ACTATGCTAGTAGTAGTATATTGTTGACTATATATTGATTACTACATTGATAGTGGTAGA TTATTATTGATTATATATTGAGTACTATGTTGATAATAGTAGCATAGTATTGATTACATA ACGATTACTACATTGATAGTAATATATTGTTATTGATCATATATTGATTACATGCATTGA TAGTAGTAGTGTATTATTATTGATTATATATTGATGACTATGTTGATAGTAGTAATCTTA TTATGGGTCATATATTGATTACTGCATTGGAAGTAGTAGTGTATTATTATTGATTATATA TTGGTTACTATGCTGATAGTAGTAGTATCATCAGTAATAATAATCAATAATGGAAACCCA TTGGGACAAGTCCTTCAGAGGCTGTCTTTGAGGAGCCCCATGGTAGGTGGATGCTTTCTG GGTGTCTTTTATCACATCTGAGTGGAAATCAGAATCCCTTCTGTTTCCTTCTCAGATTCG GTTCCAGTGCAAAGGTCGTCCACTTTTTGGGGTCCATGAAACCTTGGAACTACAAGTACA ATCCACAGAGTGGCTCGGTGTTGGAGCAAGGCTCAGCGTCCAGCAGCCAGCACCAGGCGG CATTCCTTCATCTCTGGTGGACGGTCTACCAGAACAACGTGCTGCCCCTTTATAAAAGCG TCCAAGCGGGGGAAGCACGCGCGTCTCCTGGTCACACAGTAAGTGGGGGATTCCCTTAAA ACCCGTAGCTGAGGACGAGGAGAACATCCTTGTCACCAAGGTCTGGCGTGGTTTTTTTTT GAAATGCCCCTTTTTTGTCTAAATACTGTATTTCATGGAAAAGAATACTGAGAAGCAAGC ACCTGTTAAAAAAATTTTTAAGTTTTAGCTCAAAATAGAGAATGCCTAATGACTGGAGAT CCTGTTTTGATGTGTAGGCCTGGTGCAGAAATAGGTTATTGAAATTAGCCATCCTCATCA GAGTAAGAGACACTCATGGACAAGTGGTTCACAATGACTGATTACGACGTCATTCGGGTC AACACTTTCCACTTGAAACCATCATTTGAGATAGCAGTTGGAGGAAGTGTCTGAAGAGGA TTTTGTAAAGTTTTGATTGACACCAATTTGATTGCAAAGAATATAATGACAGCCCCTCGG TGTGCTAAATGGTGGAGTATCTGCAGTGTGCTGAATGTAGGCTGCATCTGCCTTGCAGAA GACCTCTTGCAATTAGGACTCAGGAAACTTCTTATTCCTAATGGCTTTTTTCACTAAAGT AAAAAAAAACTTGAGCTTTTTTTTTTTTTTTTTTTTAACTAGAGCATTTGTACTAGAGTA CCAGAGTATTTTTTAACTAGAGTAAAGAAAACTAGAGTTTTGTTTGTTTGTTTGTTTTTT GAGACAGAGTCTCACTCTGTTACCCAGGCTGGAGTGCAGTGACATGATCTCGGCTCACTG CAACCTCCGCCTTCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGGAGCTGGGAT TACAGGTGCCTACCACCACGCCCAGCTAATTTTTGTGCTTTTAGTGGAGACGGGGTTTTG CCACGTTGGCCAGGCTGGTCTTGAAGCTCTGACCTCAAGTCATCCACCCGCCTCAGCCTC CCAAAGTGCTGGGATTACAGGCGTGAGCCACCAAGCCCGGCCTTTTTTTTTTTTTAACTA GAGCATTTGCTAGTACAACAGAGTCTGCTATCAGCACATGCATTGCCTGGGAAATTGAAA AGAATCCCTATTTTAATTTTTAGTATGGTTTTTTATTTGGGTGGATCTAGGCTGCTTTTT AAGGACTGCTGAAAATTTCTCTCACCGAGTGACACTAGCAATGGACGTTTATTTGTATTC ACTTCACAAACATTGACTTGTCACATATTTCCTGCTGGGCGTTTTGCTAAGTACTGGATT ATTAAGTACTGGATTACTAAGTACTGGATTACTAAGTACTGGATTGCATAGGAGGGAATT TTAAGGCTTAGTGTCAAACGGTCCTGAGAAAGAAAACATTTAGGACAATTATTTAATGAT TGGCAGATGGGAGCTGGGAGCCCTGGCTACACAGGGCCCCACCCGCCCCCCAGGACAGCA GGTGAATTGAGGAGACATAGGGAAGACTCACTCCACGTGTGTGTTTTTGTGCAGCTTTGC CACAGTGATGTGGGGGGGCCGTGTGCGGATTCAGCCTCTGGTGTTGGAGAGCCGTGTGAA AATTCAACACCCAGTGCGGGCGTGCCGTGTGCAAATTCACCACTGGGTTCTAACCAGCCT GCTCAGGGCCTTCCGGAGCCGACCCAGATAGTGGATGAGACCCTGTCCCTACCTGAAGGA CGCCGTTCAGAAGATGTAAGTACCTGCATTCCTCACAGGTGTGATAGTCAGACGCTGGCT CGCAGTGAGAGAGCAGAGAGAGCCGGCTTCCCTGGCTCCCTGGGGAGGGGAGATGGAGGG GAAGGGCTGGTCTTTGGCTTGCTGTGGCATTCAAGGCTCTGCATTTATTTTTGCATTACG GCACACCGAATCAAGCTCACCTGCTGAAAGATGTCTATGCCCCAATCCCTAGGACCTGTG AATGTCACCTTGTGTGGCAAAAGGGCGTTTGCAGTTGTGATTAAATGAGGGACCCTGAGC TGGGGAGGTATGGTCTTGGATTCTGGGAGTGGGCTCTTAGTCATCACAAACCTCCCTTCA AAGAAGAAGGTGGAAGTGTGAAGGTCAGAGAAGGAGTGTGAAGCTGGAAGCAGAGGCCAG AGAGAGAGGGGATTGGAAGACGCTGGGCTGCTGGCTTTGAAGATGGAAGAGGAGGCCACG AGCGAGGGAATATGGTGGCCTCCAGAAGCTGGAGAAGGCAGGAAATGGATTCTCCCCTAG GTCCCCAAGAAGGAACCAACCCTGCCGACAACTTGATTTTAATCCACTGGACTTCTGGCC CCCAGAACTATCAGATGGTCAGTCTGCCTTGGTGTAAACCACCCAGTTTGTGGCTGTTTC TTACATAGCAGCCTCAAAAATCTGATGCCACAAGGAGACAGATGCTCAGTCTCTCGCAGT TTACAGATTCTGGGGGAGCCAGAGCTCTTTCAGGTTCAAAAAGGGAGGCTTCCGTCAGTG CCCCCTCAACCCAACTGCCTGGCCGTGCATCCTGAGAGGTTTCAGCCGAACCCCTGACTT GAACAGTGGTTGAAGTGAAGATGAATTCCTGCCGGGGTTCAATGTTCAAATGAATGTTGA CCTGCACAGTGGTGTCTGCTGAGGCCGAGTCTGCAGCACTTTGTCCCCATCGAAGAAAAA TGAAAATACACCTTACTTGCAAAACAAATAATGGAGGCCGTCATTTCTCCAGCTCCAATT TCTAGGTGAATACTTTGGAATAATATCTTGTGTTTAAAGATTTCCTGGGGCCAGGCACGG TGACTCAACACCTGTAATCCTAACACTTTGGAAGGCTGAGGTGGGAGGATTGCTTGAGCC CAGGAGTACGAGACCAGCCGGCAACACACTGAGACCTCATCTCTACAAAAAAAAGTCAAG AAATTAGCCAGGCATGGATGTGTGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAG GAGGAATGCTTGAGCCTTGGAGGTCAAGGCTGTAGTGAGCTATAATCTCACCACTGCACT CCCGCCTGGGTGACAGAGCGAGACACTGTCTCAAAGAAAAAAAAAAAGAAATCTTTTTTT TTTTTGAGGCGGAGTCTCTCTCTGTCACCCAGGCTGGAATGCAGTAGCCCAATCTTGGCT CACTGCAAGCTCTGCCTCCCGGGTTCACGCCGTTCTCCTGCCTCAGCCTCCCGAGTAGCT GGGACTGCAGGTGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGG GTTTCACTGTGTCAGCCAGGATGGTCTCGAACTCCTGACCTTGTGATCCGCCTGCTTCGG CCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACCACGCCCGGCAAGATTTCTTGTTTT AAATCTTTACCACTGATCCTAACAAGTTTCTCAACAGAATTATTTTGAGATCATACTTAG GGAAGGATCTGGGGACTGGGCTGAAGGAAAGTGATTCTTTTCTGTATACTTCAGATAGCT CCGGGAGAGCCGTTTCTTGTTGCTTATAAACAAGTGACCTTTAGATTTTGCACACATTGC TCTGGAAGACACCACACGCTTCACTGTACTCTGGCGTAAATTATGCTCTGGCAACTTTAT GCATGAAGAATGTCGGAGTGGTGATTTCACATTGACCCAAACACATTGAAAAGATGTTTA GGTTCAGATGGTGAAGACTGAGGAGGTGTAAAATGCGCTTTTCTGGTTTTTCATTCCTCA TGGTGTGCCCTGAGCATACCATAGCCTGGGCCTGGCCCCAGGACGTGCCTCATGCGAGTC AAGTCAAGAGCCTCTGCTTGTTCCTGCTGGAATGTGAAGAATTCCATCAGTGGAGCCCTT ACATGATGTGCAAAACGGCTGCAATTGTGCTGAGCCATGCTCGTTTCAGGATGTCTAAGG AAAAATCGCATTTACATTAAATGTTTAGTAGGCAACCAAGTTTAGACTGTAAACCAAAGA GTATCCAAGAATGCTGTGGCATTCAAGGCTCATGCTTTTATGTGCATTACAGCACCTTAA GGCCAATAAAGGGGAACTCCCATCCCCTGTTGATGTGTATTGAAAATAATTGAATGCTCA AACTCCTAGCCTAAAAAAGAAATATTATCGAATGCTTCGAAAACATAAATTTAGGAAGTG TATTTTGCCAAGGTTAAGGACACACCCGTGACACAGCCTCAGGAGGTCCTGACGACATGT GCCCACGGTGGTCGGGGCACAGCTTGCTTTTATACAATTTAGAGAGGATGAGGTATCAAT ATGCGTAAGAAGTACATTGGTTCAGTCCGGCAAGGCGGGACAACTCAAAGTGGGGCGGGG GCTTCCAGGTCATAAGTAGATAGAGGCAAATGGTTGCATTTTTTTTTTTTTTTAGTTTCT GATTGGTCTTTCCAAAGGAGGCAATCAGATATGCATTTATCTCAGTGAGCAGAGGGGGGA CTGAATAGAATGGGAGGCAGAGGCCCTAAGCAGCTCCGCTCCCAGCTGGACTTTTCCCTG CTTACTGATATTGGGGTTCCAAGATTTACTTTCTTCACAAGACTCTATTGAGTCCTCAGA AAACGGTTTTCAAACCATCTTTCTGATTTCCGGTTGCGTAATTTTAATCTTATTCCGTCA CTGAATCTTGTACATTAGTGGTTTTGCAAACTATGGCCTGAGGTCTCTCTGAATAAGGAT CATTTTAAAGGATTGTGTTTTTGCAGATGATCTTAGAAGCATTCTTCTTTTTCTTTCTTT TTTTTTTTTTGAGATGGAGTCTCACTCGATCGCCCAGGCTGAAGTGCAATGGCGCGATCT CAGCAGCTCACTGCAACCTCCACCGCCCGAGTCCAAGCAATTCTCCTGCCTCAGCCTCCT GAGTAGGTGGACAGGCATGAGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAAAGAC CGGGTTTCACCATGTTGGCCAGGCTGTTCTTGAACTCCTGGCTTCAAGTGATCCACCTGC CTCAGCCTCCCAAAGTTCTGGGATTACAAGTGTGAGCCACCATGCCTGGCTATTAAAAAC ATTCTTAACAGTTTATTCTGAACCACAGTGAGCACTCCCTCATTCGTAAGGGCAGCCACC CTCTTTCAGAAGCAAGTGTGTATTCTCCACCCTTCAGCCCCTGGAGGGATTTCCACGGAT TGTCACAGCCCCTGAAAACAAGCTTCCCAGGGCAAACAGTGGTTTTCCAGAGACTCCAAA AGGGAAAACAGTCAGGACGCTCCAGTCCCAGCTCCAGCCCAAGTTGTAGCCACACCAATC TCTGCAAAAACAGAACCATTTCCAGAGTGACAGCACTTAGCACTCTGGTTTCTCTAAAAC AGCGCCCGTCATGTTCAATTCATATTAATCTCGATGGAATTGTTGCCGTGGATTTTTCTT GACATAAGTCACTTCTACTTTTACTTTGGATTCATAATTGTCGATGAGGTGGCAACTTAA ACAATAGATATGTAGCTTCGTGTTTGTCCGTCCGTGAGCCACCTTTCAATCAGAGCCAGT CAAGCCAAACCTAGGAGAGACTTTCCCGTGGAGGGATTGGGGCTTCTGAGGAAAGCTCAT GGAGAGAATCGTGATGACAGAATTGAGGATCATCCTGCCTTGATGCCCAAGGAGGTAAGC AAGGACACAAAAGCACGCTCATTTCACCCCAGTTAGGTGGTGTCTATTATCAAAAAGACA AAAAATATCCACTGCTGGTGAAGATGTGGAGAAAGGGGAACTCTTTTCCACTGTTGATGG GGATTAAAAATAAGCACAGCCAGGATGGAGAAGAGTATGAAGGTTCCTCAAAAAACTACA AATAGAACTACCACATGATCCAGCCATCACCACTGGGCATTTATCCGAAGGAGAGGAAAT TAGTATATTGAAGGGACATCTGCCCCCCGTCCATGTTTTTGCAGTTTATTCACAACAGGC AAGATACAGATTCAACCCAAGTGTTTGCCAAAGGATGAATGGGTAAAGAAAATGCCATGT ATAGATATACCATGGAATACTATTCAACCATAAAAAAGAAGGAAATCCATCATTTGCAGC AACATGGATGGAAATAGAGGACATTATGGTAGGTGAAATAAGCCAGAAACAGAAAGTTAA ACACCACATGTTCTCACTCATCTGTGGGAGCTAAAGAAATTTAACCTCACAGAAGTGAAA AGTAAGGCCAGGCACAGTGGCTCACTCCTGTAATCCCTGCACTTTGGGAGGCTGAGGCAG GATGATTGCTTGAGATCAGGAGTTTGAGACCAGCCTGAGCAACATAGCAAAACCCTGTCT CTGCAAAAAAATACAAAAATTAGCTGGGTGTGCGGTACTTGCCGGTGGTCCCAGCTACTC GCAAGGCTGAGGTGGGAGGATCGCTTGAACCTGGGAGGTCGAGGCTGCGGTGAGCCGAGA TCACGCTGCTGCACTCCAGCCTGGGCAGCAGAACAAGACCCTGTCTCAGTAGAAGAGAGT GTACTAGAGACTAGGAAAGGTGGGGGAAGGAGAAGATAGGGAGAGATTTGTTAAAGGATA CAAAATTACAGCTAGACAAGAGGAATATGTTGTCATGTTCTATAGCCCTGTAGGATGACT ATAGCCAACAGTAATCTATAGTTTCAAATAGCTGGACGGAGGATATTGTATGTTCCCAAA AGAAAGAAATGGTACATATTTGACATGAGGGATATGCTAATTACCCTGACCGGATCACTG AATATTGTAGGTATTGAACCATCCCTGTGTACCCCATGAATATGTACAATTATTATGTGT CAATTTTTAAAAAGTAAATTTTTTTTTTTTAAAAAAAAGTATGTTCAACAGCCAGCAGCC ACGAGAAGGTCATCAGCTGGTTTCATCCACAGCAAGAGATTGCTGGCTCCAAATCCCCAC CCCATCCTCAAGGGGCAATATTGCAGAAAGGAGGAGGGTGGGAAAAAAATCTCAAGAATT GGAGAATCGCCGGTTTCCAGGGCCCAGAACAAGACCCAGGAGGAGATGAAGATCACCCTT GCAGGTAGAAGCTGTCCCTGTCTGGGTAGTGCTGGGGACAGTAGGTGGCCCTTCTGCTGT CTGTCTGAGCATGAGCTCAAGGCCAAGGGTAAGATGAGGGGAAATGACCCCCAGCTGGGC TGAGCGTACTTTGTTTAGGGTATTTAAGCAGTTCTCAAAAGTGATTGCAGAACCTGTATC TCCCATCTCAGGGACTCTGCCCAGCCTCACCCCTCCCTCCACCCCACTGTCATGCCCACG CTTAGGCTTCAAAACATCAATGGAAGATGATAGTGCAGTGCCCAACTGCAGGCCCTTACA TGAATAAACTGTACATCACAGAGGGGGCGGCAAGGGAGGGGAAAACAGACAGATCCAGCT CAGATGGAATTTGATCTGAAGGAAAGTGATAAAGTGAAGAAGGGATCTGTCAGCCCTGCA AGCGGCCCCAGGCACAGCGTGAAGGGGAGGCAGGGAGAGGTCATGCTGGCCTCAGACTTG GACGCTGAAATGTTTAGTTACAGCCGGAGGGGGGACGCCTGCATAGGTCCTAGGGAAAGG AGGGGACACCCAGGCATTGGAGACCCACTGTGTAGACGACTGCGAGACATGCTTAAATAT TTAGCAGAAAGGAAGAGAAATTCGAATAGAGAGATTCAGGAATGGGAGGAAGGGATGGAG GTGAAATCAAAGCTGTTTAAATACAGATGCTCTTCGATTTACAATTGGTTTACATCCCAA CAAACCCATCGTAAACTGAAATATCTTAAGTCAAAAATGCATTTAGACCAGGTGCAGTGG CTCACGTCTGTAATCCCAACACTTTGGGAGGCCAAGTGTTGGCAGATCACTTGAGCTCAG GAGTTCAAGACCAGCCTGGCCAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAGT TAGCCAGGCTTGGTGGCGTGCGCCTGTAATCCCAGCTACTCGGGAGGCCGAAGCAGGAAA ATGGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAG CCTGGGTGACAGAGCAAAACTCAGTCCCAAAAAAAGAAAAAGAAATAGAAATATAAGCAT AAACTTAAATAACTGGGGAGCGTTATGTTGGCTGACTGCAACACAGATACGAAAAACCCT GACAGAATAAAAAGAATTCTAACCAAAAAGGTATTTTGGGCCGGGCACGGTGGCTCACAC CTGTAATCCTAGCATGTTGGTAGGCTGAGGCAGGCAGTTCACTTGAGCTCAGGAGTTTGA GACCAGCCTGGCCAACACGGTGAAACCCTGTCTCTGCTAGAAATACAAAAATTAGCCGGA AATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCAGTGCATTCCA GCCTGGGCAACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAGGTATTTTGG AGTTCCTGTGTCCACATAATTTCATCCTTCGATCTCACCCCCTATTCTCCCCACCTCTCC ATCCTAAGGTCGGTGAATACTGCGTCGGGGAAATTGACCTAAAAAAATTTGTTATGGTCT ATATATTCTCTGATGAGGGTATTTTTCTAAAAGCAATGAAGTCTTCAGGCTTTTAAAAGG AAGGGATTGGGGGGCGAGGGGAGGGAGAGCATCAGGACAAATAGCTAATGCATGCGGGGC TTAAAAGCTAGGTGACGGGTTGATAGGTGCAGCGAACCACCATGGCACACGTATACCCGT GTAACAAACCTGCACATCCTGCACACGTATCCCAGAATTTAAAGTAAAAGCAAAACAAAA CAAAACTCTTTTTAACAAAAGGTATGTTGATTGATTGGAGATTATTATATTACGGTCACA TTTTCCAAGATAATATTTGATAACACTGAACAAGGAGTTGAAAATTTGAGCTGTTTTGTA TACTAGTTATGTGACTTTGGATAAATCAATAAATATTTCTGAACATCTTAAAAAAAAAAA AAAGAGGGATGCTGTCCATACGGTATCTGATATATAGCTCACCCTCCGCATCTATGGGTT CCATATCTGTGGATTCAACCAACCTTGGATCGAAAATATTGGGGAAACAAAATTGCATCT GCACTCAACATGCACAGACTTTTTTCTCTTGTTATTATTCCCTAAACAATACGACATAGC AGGTATCAACATAGCATGTGCATTGTAATAGGTATGGTAATTAACCTAGAGATGATTTAA AGTCTATGGGAGGATGTGCATTGCTTATATGCAAAGACAGTTCCATCTTGTATCAGAGAC TTGAGCATCCGTGGATTTTGGTATAACCAGGAGGTCCTGGAACCAATCCTCCATGGATAT CAGGAGAAATTCCATTTCATTAATTCGTACTCCCGGTGGTCTTTGAAATGAGTCGTGCAA CATCACTGTCACCTGCTGTCCATTTAGTGAGTTACTCTGGGTTTTTTATTTAGGGGAGCT GAAACACAGATTTTTAAAAAAAGTTTATTTTCATAAATCGCAATAATGTCATAAAAGCTG AGTGTGCGTCTGGGGCTCTTTAGTCCAGTAGCTACTTTGGTATATATAATGATGGCAAGG TTGACGTGTTTTGGTTTTGTTGTTGTTGTTGTTTTTGAGACAGGGTCTCGCTCTGTTGCC CAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAGCCTTGACCTCCTGGACTCAAG TGATCCTCCCACCTCCTCCCAGGTAGCTGGGACTACAGGAGGTGCCACCACACCTGGCTG ATATTTTGTATTTTTTGTAGAGATGGGTTTCACCATGTTTCCCAGGCTACTCTTGAATTC CTGGGCTCTAGCGATCTGCTCATCTTGGCCTCCCAAAGTGTTGAAATTACAGGCGTGGGC CACCGTGCCTGCCCCAGATCTGTGTTTTTTAAAGTAAAGCTGAATATTAATTTTTTCCAC ATACATTAATGTATTAAGGAAAAAGTTGCAATTAGTATCTTCTCCAGCGTTTTGTCTTCT AGTATTTGGGGTAGGGAAATGTAGTTAATTAAAAGATTACAGATGTCCTTCAGTTTTTTT TTTTTTAAGCTATCAAGTTTTTTTACTCTTTTTGTAGTGCATCTTATTTTATTCATAATA CACCTTTTTGTTGAAGTATGTCTTACTTTTTTATTTATTTATTTATTTTTTTGAGACAGA GACTTGCTCTGTCGTCCAGGCTAGAGTGCACTGGTGCGATCTCGGCTCACTGAAGCCTCC GCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAACTAGCTGGGACTACAGGCA TCCGCCACTACACCTGGCTAATTTTTTGTATTTATAGTAGAGCCGGGTTTTCAGCATGTT GGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTGAGCCTCCCAAAGT GCTGGCATTACAGGCATGAGCCACCACGCCCGGCCTCTACTAACATTAGTAGAACCGTTG ACTGTGTCCCATATATCTATGACACAGTTATCTGCATTTTCTGTCAATCTTTCTCCCCAT ACTTCAGTCTACTGACCTATTTTCTAGTTAACTGATCTCTTTGGCTATGTCTAATCTGTT GTTAAACCCACATTCTAGCTTCAGTTATTATGTTTTTAGTTCAAATTAACATCAGATTTT TAGTTCAAATAACATCAATGTAGTTTCAATACTACCTTGAAAATTTTTATCTTTTTCCCC ATCTTATTTAAAGTATTTCTCACATTTAATTATAGTCCATGTCTGATAAATTACATATCT GGGTTTCAGGTGGGTTTGGTTTTGTTGTTTAATTTTGCTTGCTCTTGATTTTCACTCATT TGGTCTTTTCTTGTTGTATGATAGTTAATTTTTTAATTGACAGCCAGACATGGTAAATGA AAAAGAATTGCAAAGACAATTTGTAGCTCTGAATCATATTATCATAACCCAAAGAGGATT TTTTTTTTTAATTCATGTGATTTGATGTGATTTGTCCATACCCTGAGGTAGTTTGCCCAG ACCCTATCTGGGGCTGAGCTGGAGGGAAATTGGGCTTCAGTGTTTGTGATGACCAGTCTA TTTCTGGTTCTCCTCTCAGTGAGGTCACAAAAGAAAGCTTGTGGTGTGTACCAGGGTCCC TCATTGGTCCTGATTATTAATATTTATGGACCCCTCAGCCTCCTAGCACTGCTGGCAACT CTACTCAGTTTCTCAGCTTCCCAGCCTCTTATTTGCCCTGAGTGGAAGTAAGGTACCAAA TGTGACATTTACCTCTTCTGTTTGTCTCTGGTATCTTCACTCTTAATTTTGTGCTGCCTT AGTAGCTCTCTGATGCACTTAAAAAAAAAAAAAATTCTAGGCCAGGTGTGGTGGCTCACA CGTGTAATGCCAGCACTTTGTGAGGCCAAGGCAGGCAGATCACCTGAGGTCAGGAGTTTG AGACCAGCCTGGCCAACATGGTGAGACCCCCATCTCTACTAAAAATACAAAAACTAGCTA GGCATGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCACT TGAACCTGGGAGGGAGATGTTGCAGTGAGCCGAGATGGTGCCACTGCACTCCAGCCTGGG CAACAGAACGAGACTCCGTCTCAAATAAATAAATAAATAAATAAATAAATAAATAAATAA ATAAATAAAATTCTATATACATTATTTGTGCAGCCTTTTTAGGTATTTTTGGCAGAAGAC TTAGTGTGAAACAACAGCTTCACCATTTGCTGAAAGTGGAAAAAATCTCATTTCAGTTCC TGAGCTGATACATATATATTTGTATTTTTAGCATTCACCACCTCCAGCAGTAATAACTTT CACAAATTTATAGCCCATAATGCAAAGGAGTGCTTCCTTTTTTGCTGTAAATGTTATCTC CTTGGATTGTGTACTGGAACATTCTGTGTCTGCTGTCTATCTGTTCCCTGCCTCGTCTGC CTTTACGATGTCCTCTCTCAGCTTTCATCTTCCCACACAGAGCATTTTGTTTTAAGCATC TCTGCATATCTCAGCCTCTTTCCAATGACCTGAGAATTCTTCTCTGGCCTGCCTCCAGTT TCAGAGTCCCTTCTTTCAAGGTGACCCCATCTTCAGTCAGGCTTTTAGGGGATACATCAG TAGAATAGTTATTACCTAAGGATAAAAAGAAATGCAGTTTGTAAAAGTCACATTTTATAT TCATGCATTCACAAGCTTGCCAAAAATGTTCTTAAGAGCGGACTTTGAGATTGCTGCATT CTCATCTTAAAATTTCTCTCTGCATGATATGCAAGGGGGAAGTGTCTACTTTTTACTAGT AAAAATAATGGCCATATTTATTCATAAAAGTTGGTTTATGTTTCGGCTGTTAATATTACT TGTTAAGTAAGCCTCTGGGTCTTGATTAGAAACATTAGCAAGGGCTGACTGAACTTCTCT TCCTCGTTTAAATTCGTAAGATTAACACATCTGCAGAAGGCAAGCTGAGAACTTGCATCA TTATTTCATCCTCTGTAATCAAACATATAACCCCGAGTTAAATCCCTTCCGAGGAAGGAT TATACTTCATGATCGGCCCCGTGGAACTTATTTATGTGTTTATCGTTGGGAGAAATTAGA TGACAGAAACAGATTGACATTTTCCCTAATCCATTTCCAGGAATGGTTTTTTGAGCACTT ATTCTTTGCCTGTCTGGCTGCTTCATTTATCCATCACAATAAGTGTCTGTGTGACATCTC ACTGAAAGCCCCATGACTCAGAGAGTCATTTCTGCAGGTCCTTTTCCTTGATGGGTCAGT ATTCAAATCCAGGACATCCCTCTACCAGCCCTGGTTGAAGAAGGAAATTATTCATTTTTA TGGGATTCATATGGTTTATGATAATGCAGTTATTGCATTCGTCATTTTTTCCCAAGACTC ATTTTGGTGTTTTGCAAGGCGCATACCCAAATCCCGCTCTCTCACTTGCTAGTTCTCGTA TGTTGGGCAGTATCTCTGTCTGCAGATTAAACTTTGCAGCAGTAAGAGGGAAGGCTCAAC CTGTCTGCCTCATAGGGCTGTCGCGATTAAAAGGAATCAGGGCTGAGAAGTTTATGAGTG TCACTCAGCAGCCAGCCATGAGCAGCCACTAAAAAAGGAGTCCTGTTATCATGGTTGTCT GATATCTTTGACAACTTATAATTTTGTGTTACACCATAATTCTTAGAACTTAATTTTATA TTTGGATTTTACATACATAGCTGAGATCTGAAAGAAGAAGCCCATATTTTATTTAATGTT AATTTTTAAAAATTTCTCTCCAGCTGTATTGAGGTACCACTGACAAATAAAAATTGGTGT GTATTTAAGGAGTACAATTTGATGCTTTGCTGTATGTATACATTGTGAAACAATCATTGT ATCAAGGTAATTAACATTTTCATCACCTCGCATAAATGCTGTTTTCTCCTCCTCCTCCTC CTCTTCCTCCTCTTTCTCCTCCTCCTCCTCCTGCTGCTGTTCTTGGTAATGAGAACACAT AAGATCTACTCTCATAGCAAATTTTAAGTACACAATCCTATATTGTTAACTGTGGTCACC ATGCTGTATGTTAGATCCCCAGAACTTATTTATCTTGTGTAACTAAAACTTCATATTCAT TCCTTCACCAACATGTCTTCATTCTAAGCACCCCGCCCCCAGCCCCTGGCAACTACTGTT CCACTCTATTCTTCTGTGAGTTATTTAAAGTGCACTTTCGGAGGCTGGGCATGGTGACTC ACCTGTAATTCCAGTACTTTGGGAGGCTGAGGCAGGCAGATCACTTGAGGTCAGGAGTTC AAGACCAGCCTGGCCAAGATGGTGAAACCCCATCTCTACGAAAAAATACACAAAAAAAAT TAGCTGGGTTTGGTGATGCATGCCTGTAATCCCAGCTACTCAAGAGGCTGAGATAGGAGA ATCACTTGAACCCAGGAGGCAGAAGGTTCAGTGAGCCAAGATCATGCCACTGCACTCCAG CCTGGGTGACTCTGTCTCAAAAATAAAATAAAATAAATAAATAAATAAAATCAATTGCAC TTTCGTGATTATGAGTTAGAATAGTCAAATTAAAAAAAAGGTTCATGATTACAGTGTTCT CTTTTACATCTTAAAGTTTCAGTAAATCTCACTAATAATGACTTTTGGGGGTGTTCAGTT TTTATAGATACCTTTTTTCTATTTCTTTCTGTGCTCCTGTTCCTCTGCCTTAGGGCATTG CACATGCTGATCTGCTTTCACGTGCATTTTTCAGCATGTTCTTCTTCTTACTTCATTTCC AGTCGTTCTACATCATTGGCTTCTACTCAGCCTTCAGGCTTCATTTTAGATATTACTTCC CTAGGAGTGTCTCCCCCTTTAGACCAGGTGAGGTCTCTTGATAACATTTTCTTTCCTAGA ATTGATAACCATTTTCTTTCCTAGAATTGATAACCATTTTCTTTCCTAGAATTTCTCATG GCTTGCCATTTTGTATTTGTTATTTGTTGATTTTCTGTCTTCTTTGACAGTAAGCTTCAT GAAGGTGCAGATCATATCTGTGTAGGCCACTGTTTAATCTTCACTACCTACCTCTCCATA AACACCTGTGAAATGCATACATTCATGCCTCGATTAGGAGAATGAACTGGACATTCTCCT AAAAGGGAATGCTAGGATCAGAAATTTGGGAGCTGAGTATCCGAGTGACTGATCTCCACC CCAGCTGACATCACTCAAAATCTCTGGGATCATGGCCTGCGGGTCTGCATTTGAAGGATT ACAATTCTCTGAAGTTGGCCTGGTGCAGGCAAGAGGGGCTCATGTTGAGGCTCAACCCCA TCCACCCCCAAGAATTCCACAGTGTGTTTTCAGTGAGGATGTCAGTGTTCTCTTATCTCT GTTGCTCACACTCATTAAGCTAACTGCTTTGTGACCTGACCTGATGGGGGCCCCAGTGTT TGGACACAGGTTTGCTTCTTGACCCTGTATTTGTCAAGGTAGGCTAGCTGCTATAACAAA CAGCCCCCAAATAAGTAAAAGTTTATTTCTCATTTGTATCACAGCCAGCTGGGGTGGCCA AGGTATCCTCTACCCCATGCAGCCTTTCAGGGATCCAGGATGCTCCTATTGTTGTGCACC ACCTTCTAGGGCAGCTCTTCTCAAGTGAGACTCCTTGGGAGGATTAGGCGCTGTTGCTGA CGGCAGCCACTGTACGTAATGCATTAAGTAATCTCCTCCCCATCTAGCATGGTGTTAGAT ATGGACCATCCTTGGGAGAGTTGAGAAAAGAGTCACCTGATTTGTTCTCTGTTTGGTTTT ATTTTCTTATGGAGGCCCAGTTCAGAGAGGGTGGAGGGATCTTGTTTTTCACCTGGCTGG TGGTAGAAGAGAGGATAGGAATATCTTATTCCTCTCGTTGCCCAGCCCAGAGGTGACTCA CATCACCTCCTCACATTCACTCACATCACCTCCTCACATTCACTCAATCTGCTTGTGGGA ATCACTTCCATGGTCCTGTCCAGGTGCAAGGAGGTCACAAAATGCACTTAGACATTAGCC CGAGAAGAAGAAGAAACAAACACAGGTATTGGTGAGCATATCACCTTGCCCCAGTCCTAT CCCATATCAAGTTGTATTTGCACCATAGAGGCAGAAAAAAATGGAGTGGGTATTTTCAAT TAAGTTGCATTTATTTGCACGAAGGTTTGACTTAACTTGCCTTTGCTCTTTCTTTATAAC AGATGATAGCTTGTCCTGAAACTGAGACTCCTGCCGTGATAACGTGTGACCCACTGTCCC AGCCTTCCCCTCAGCCTGCAGACTTCACAGAGACTGAAACCATCTTGGTATTCCTCATCT ATATGACCTACACATGGCCAGCTCTCTTATTGCTTGTTATTTTCTCACAGGGTCTATCCC CATTACATACCAGTGGGGGCGCCATAGGCTTTTAAAAATTCCTCCCTTTTTTTTTTTTTT TTTTTTTTTTTTTTGAGTGGTTTCTCCCACCTGGAATAAGTTGTGTTATAATTAGTCTAT TTCTCTATTATCCAGGTGGATAAGGAATCTGGCTGTCTGTTCGAACTTATTGTGGGGTTT TCTTTTTCGTCATTTTGTTATTCTCTTCCACTTTGCTTAAAAAAATTAATAAGAAAAAGA TACAGCGTCTATATAGCATCTATGTCTCCATTAATTTTTTTAAACTTTTGATAGGACTTG CACCATGTCTAAAATCAATATTCCATGACTATGGATTTTATTTTAATTCTTTTTTTCTCT AAGTTTACCCTTATGAATCTGGGCTTTTATTGCCACATATCATCAGAAAACTGGCTTTAT GGACACCCCCCTGTTTTTAAACTCTCAAAGAGACTATCTTAGTAAAATGCTTCTGTAGGC ATTTGGTATAAACAAGTCAAATCTCTCTCTGAAAATTTAACTTCCATGAATTGCATAAGA ACTTGTAGCATCTCCTCTTGTCTGAGACTTGGTGGATGGCTCAGAAAAAGTGAGGGGAGA GAAGCTGAGCTATTTTTAGCATTCCCAGAAAAGAAGATCGAGTACAGTCCATCAGTTTTT TTAAAAAAGTTAATTATAGTGCCGGCCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTG GGAGGCCGAGGCGGGCGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGT GAAACCCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGT AGTCCCAGCTACTCCGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGTGGAGCTT GCAGTGAGCCGAGATCACGTCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCCGTCT CAAAAAAAAAGTTATAATAAAGATGAGGTCTTGCTATTTTGCCGAGGCTGGTCTCGAACT CCTGGGCTCAGGCAATCCTCCTGCCTTGGCCTCCTAAAATGCTGGGATTACAGGCATGAG CCACCGCGCCTGGCCTCAACCCAATAATTTGATTTTATTTTACCCCAGGATAAAGAGTTC TCCATCATTTAGGTTAGGGCTACAGTTCCCTGCAGCCCACCGCAGACTAATGATGGAATG GTTATGTTTTAGCAGCCAGCAAATAAAGTCGAAAGTGTCTCATCCGAGGAAACCTTCGAA CCAAGCCAGGAACTCCCTGCTGAGGCTCTCAGGGACCCCAGTCTGCAGGATGCACTGGAG GTGGTATCCAAATTCTTCCCCTTGCCCAAGGCTCCCGGTGGGGGCCATCCACCGTCACTG AGGTCAACTGCATGCACACAACAGCTGTTAATTTTTCAGCCTCATTTAACAAAAAATAAG AATCGGCTTCCCTCTTCCCCTGCCTCTGATTCTTCTGTCTTCTCTCTGGCATTTGCCTGG GGTGATCGGCCGACTCTCTTTTGCCATCTTCAAGTCTGATCATCACGCTTTTTCTCTCTT TAAAAGCTGTTCTGCAGAAGGGATCAGGAGGGAAGTTGAGGGACTGTGGAAATTAATGCG TAGCAATCCATTTTCTGAAATGAAGAGATTAAAAGCTGAAAATTGGAGGGAGTGGGGCAT GCTAATGTTCGAATCCAAATGGGGCATGCAAATAATTTCTTCTTTCAGGATGAAATGAGA GATGCATGCTTTCTGTTCCTTCCTCTTAGAGATGTTTTCATCTTCAACTACGTTCTCTCC ATTGATGCATTTAATGAAAGCAATTGCTAACGTTTTCTCTTGCTCTTTAAGCATGATCTA ATAATGCCATTTGGTCTTTAAGTAACAATCAATACAGCTCTAGAGCTAGGTTTAGGTCTA GACTGAAAGTTGGTATTGAACGCATGTTTAGAGTGTGACCTACTGTGTTGGCTAAATGCC TTCCCTGGACAGTCACCCTTGGAGAAAATGTGAACTTGTTTTTCTCATTCTTACTTGGTT ACTGTTCAAATGCAGCATTTTGAACTTAATTTCTAGAGCTGTTGGTTGAGGTCCAGGTTT CTTATAAACATGTGAATGTATCCCTTCAGCATGTTCCATCCTTGTGGTCATCATTTGAGG CTCTGTGAATTGAATCTGTAGTTATTAGTGAGTGACAGGGCATCAGTGTGAGGTTGGGTA AGACCTACGTTGGACAGCTCAGCCATGTGGTAGGTTTGGGATCCTGGATGAGTTCATTAC TTTTTCTTTTTAAAAATTATTATTATTATTATTATTATTTAGGGACAGGGTCTTGCTGTG TAGCCCAGGCTGGAGTGCAGTGGCATGATCATAGCTAAGCAGTCTTCCTGCCTCAGCCTT CCAAGGAAATGGAACTACAGGCATGGGCCACTGCAACCAGCTAATTTTTTATTTTTATTT TTTGTGGAGTTGGGGTTTCACTATGCTGTCCAGGCTGGTCTCGAACACCTGGCCTCAAGT GATCCTCCTTTTTTGGCCTCTCGAAATGCTGGGATTACAGGCATGAGCCACCGCGCCCAG CCTGAGTTCATTACTTTGCTTCAGTGTTCATGAGGTGGAGACTGGGTTGCCCACCTCACA GAATTGGAAGGAGGGGTATTAAAAAGGAGAGTGGTATAGGGAAAGCCCTAGTTAGTGCTT GGCTCATAAAGATGAGGAAGATTTCGGTCATTGATTTGCTAAACCGGGGCACTTTGACCT CCTGTGTGTCCACACTGTCCTCTAGGGGAACTTTATTTAGTATCTTGTATAATACCCTAA TTCATAACATTGGAGCAGCTTGTTGTTTTCTTGGATACTCATCTCTTGTTAGCAGAAATG TCACAATCACTGTGCTGTTTTGTCTTGAAAACTAGTATAAGGTTGGGTGCTGTAGGTCCT GTTAATTCCAGAAACATTTCATTCTCAGGAACTGAATGGATCTAAATGCAAGTGCTCTTA GAGGGGAGAAATGCTGCAGTATCCTGAAGTGGACTTTTTAATTTATTTGTTAACTCTTGC TATCACCTTAATCAATAGGATGGCTGTCTTTAAATAAAATATAATATATGGGAATGAGTG TAGAAGGCAGAATCTTATATGTAAAAACCTTCTAAAAACACTGCGGCAAGTAATTAGAGA AGAAAGTAGTATATGCCTATGGTGTAAAAACTCAAATTTATCTTTCTATATATCTATCTC TATACATATCATGTATCTATCTATCTACCTCTTATCTATTTTCTTTTTTTTTTTTTTTTT GATGGAGTCTCACTCTGTCACCCAGTCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCA ACCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCCGGGTAGCTGGGACTA CAGTCACCCACGACCAAGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACC ATGTTGGCCGGGCTGGTCTCGAACTCCCGACCTCAAGTGATCCACCTGCCTCGGCCTCCC AAAGTGGGATTACAGGCATAAACCACCACACCCGGCTATCTATCTATTTTCTATCATCTA TCTCATCTATATATCCATTCATCCTCACATCTAGATAATAGATACATAGATATAGAAGAG ATAAAACATAGGTAGTAGATAGAGATGATAGATAAATGAATGATAGAGTGATAGATGATA GATAGGTAGATAGGTAGAGAGATATTTTAGATAAATAGATAAATGATAGAGTATAGAACG GATGGATGGATGGATGGATAAATGGATAGATAGATTGATAGAAAGTAGATAGGTAGGTAG AGATCATAGATAGATAAATAGGTAGATAGATGATGGAGTGATAGATGACAGATGATTTAT TGATAAATAGAATGGATGGACAGATGGATGGATGGATGGATGGATGAGTGGATAGATAGA ACATAGGTAGATAGATGAGATAGATGATAGATAATAGATGGTTGGTAGATGAGATAGATG ATAAATAGATGATAGATAGATAGATAGAAAGATGTGTGTGTGTCTATTATTGTTACCATC TTTAAATTTTTAAGAGTCTTTTTCTAGTTCTTGGTAAGAAGTGTTTAAAGCAAATGTATT TGTTCTTTTTGTTGACTCATCTGAATGCCAAACAAAATGTGTGTGTGTGTGTGTGTGTGT GTGTTGTTACACACTTGCATTTTCATCTGTTTTTTCACATGACCCTTAAGAAGGCAGGAA CTCTGCCATTGAAAAAACTATCTGAATTATTATTTAAATTCCTTTGCCAAGCAGTCCAAA TTCTTATAGGCTTTACTTACAGGAGGTGAGTTGTTTTTTCATTTAACGTAGTTTGGTTAT TCACTGTCATACAAAACAGAAGTTTTGGTGGGTGAGAGTATTAAATTAGTGTGTGTGTGT GTGTGTGTGTGTGCACATGCGCATGTGTGCATGTGTGTGTTTAAAATGGTTTAGTGGCTA GAAATGAAAACAATTCTTCAGAAAAAGAGAACATATACAATTACATTTTATAAAATTTCA AAACACTTAAGCAAAAAAAATTATCTTCTAAGCATATTATACTAAATCTAGTGTATATTT AGCTCAAAAGAAAAGTGCTGCTGGGTGTGGAGGCTCACACCTGCAATCCCAGCTCACTGG GAGGCCAAGGCAAGAGGATTGCTTGAGCCCGGGAATTCAAGACCACACTGGGCAACATAA TGAGACCCCATCTGTGCAAAAAATACAAAAATCAGCTGGGCATGGTGATGTGCCCTGTAG TCCCAGCTACTGAGGAGGCAGATGTGGGAGGATCTCTTGAGCCCAGGAGGTCAAGGCTGC AGTGAGCTGTGACTGCACCACTGCACTCCAGCCTGGACGACAGAGACCCTGTCTCATTAA AAACAAAGTGCTAGTGATTCGCAATCTCTTTTTGAGAACTGAGATGCATCTTTCTGCGGG ACCCTACACTGGATGGGTTTTAGCAGTCTTTCCCTCGATAATGGACAGCTGCAAAAACCA TCTCCCACTGACTGTCTTCCCTAGGTCGACCTGGCCGTCTCTGTTTCCCAGATCTCCATC GAAGAGAAGGTGAAGGAATTGAGCCCCGAGGAAGAGAGGAGGAAGTGGGAGGAAGGCCGT ATCGACTACATGGGGAAGGACGCGTTTGCTCGCATCCAGGAGAAGCTGGACCGGTTCCTG CAGTAATCCGGCAGCTGGTGGGCGTTGTGTGTAGTTAGACAATGTCCTGTTGGGTGGTCC TGTTGCGTGGAGATCTCCTCTGGTCCTTTCAAAGGGAAACGCTGTTGAACCTTGTGCCTC TATTTATGCTTAATCCATTTGAGTGCCTCACACAAAAAACGTAGAGTATAGAAATCCACC TTAAAGCCCCTCGCCCCAACTTCTCCACCAACGCCTTCTGGGCTTTCTTCAGAGGTCACT TCTACCCTTGAAGCTGTCGGCAAAAGCGAGCAGTAATAACATTCTAGTAGACTCTCGATG GTGGTCTCCGCTCTTGCCCGAAGGACCTCTGAAGTACGCTGGAGCTGTGTTGTACAGGTG CTGTGAGACCTACCCTATTCAGAATTAAACCTCACTGCAAATTTCCTCCCATCACGAAGC TAACAACACTAATATACGTATTTAGCACCTCTGAGGCTTTGCCATGGAGACCCATTTCTG TAGGGCTAAGGAAACATTTAGACGTGGTGACTGACTTTCATTTGGACTTGGCGAAGTGTA TCTGAGAAACACCTCGGCTGTGGTCTCTCTGCTTTAAATCCTAACAGGACTTCCTAGAGC GTTGACAGAAATTCTACTCGTGGACGTTGGGAAGAAAGATTGTAGGTGGCTTGGGGAATG TGGGTGGCTTAGAGGATCTAAACCGATTCACTTCCTGGTTGAGAAGCAACGAGGGCTTGC TCTAAATCGTTTAGAGGATAACAGGATCTAGAGATGCTCTCTGCTTGACAACAAAAGTCA GGGTGCAGTCGGTCCACCCTTGACTGCTCTTGGCTTGGTCTCTACCCTCACTACCTCAGT TCTCAATAACTTAGTGAATCACTGCCCTCCTCAAAGCCATTTCCACTCAGCTCTTTCCAG AGAATTCTCAGTTTTATGAGACGGGAAACTTTATTTCACGAGAAAGCCTCATTGTCAGAA GTATCTTCATTCAATGGGCACAATATGCTGTGTATCTCACCAGGTAGCTGTCAGGGGCCA CCGAGAGTGTCGTTAAAAATGGGCATGGTTGTAATAAAGGAGGAAAGTGCGACTTTTGAA ATGTTTGGAAGGTTTATTTCTCATGCACATTCCAGGGAAAAGCAGAGAGTAAATTAGAGA CGGGATAGGAAGGCCGTGGGAGAACTCGATCCTAGCCTGTGTCAGCTGGATGTGTTTACG TGGAGAGGCGTGGCCACTTTTTAGGTCACCTGAAGCAGTTTAGCCTTTGGATAGAGGAAC CTGCCTGAATTTATGGCATTAGTGGTGGCATTTTTTTGTGTACAAGATGTGGGTGATGGA GGGGCTGTTTCTTTTTCCGTGTGGGTGGTTAATAATCGTCAGTCTCGGAGGGCGAGGCTC GTAGGATATTTCAGGTGAGTCAGGGTTGGATGGTCATCGGCTTTCAGAAGGAGACCACGG GAATGTTCAGGGAAACAATGTCAGCTTCTCTGAGGACCAGAATTCATGTTCACGGGCAGT GATGAGTTGGCTTATGGAGTGAGTCCAGTCTGGAATTCCGCCGTGCATTCTAGCCTGTAT CATCTCATTTGGACAAATGCTGGCACGTTGAAATTAAAATGTTAAAAAACAGCCATGTGG CCTCCTTCCAG bcftools-1.21/test/csq/ENST00000381157/ENST00000381157.fa.fai000066400000000000000000000000211467060157400215320ustar00rootroot00000000000000X 54071 21 60 61 bcftools-1.21/test/csq/ENST00000381157/ENST00000381157.gff000066400000000000000000000042511467060157400211610ustar00rootroot00000000000000X ensembl_havana gene 21 54051 . + . ID=gene:ENSG00000056998;Name=GYG2;biotype=protein_coding;description=glycogenin 2 [Source:HGNC Symbol%3BAcc:4700];gene_id=ENSG00000056998;logic_name=ensembl_havana_gene;version=14 X ensembl_havana transcript 26354 52324 . + . ID=transcript:ENST00000381157;Parent=gene:ENSG00000056998;Name=GYG2-010;biotype=protein_coding;havana_transcript=OTTHUMT00000377085;havana_version=1;transcript_id=ENST00000381157;version=2 X havana exon 26354 26388 . + . Parent=transcript:ENST00000381157;Name=ENSE00002101522;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002101522;rank=1;version=1 X havana CDS 26354 26388 . + 1 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 X havana exon 27731 27857 . + . Parent=transcript:ENST00000381157;Name=ENSE00003500720;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003500720;rank=2;version=1 X havana CDS 27731 27857 . + 2 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 X havana exon 31076 31298 . + . Parent=transcript:ENST00000381157;Name=ENSE00003569036;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003569036;rank=3;version=1 X havana CDS 31076 31298 . + 1 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 X havana exon 32755 32955 . + . Parent=transcript:ENST00000381157;Name=ENSE00003507737;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003507737;rank=4;version=1 X havana CDS 32755 32955 . + 0 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 X havana exon 47043 47147 . + . Parent=transcript:ENST00000381157;Name=ENSE00003507910;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003507910;rank=5;version=1 X havana CDS 47043 47147 . + 0 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 X havana exon 52285 52324 . + . Parent=transcript:ENST00000381157;Name=ENSE00002095888;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002095888;rank=6;version=1 X havana CDS 52285 52324 . + 0 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 bcftools-1.21/test/csq/ENST00000381157/haploid-diploid.txt000066400000000000000000000005161467060157400224560ustar00rootroot0000000000000031140 A T missense|GYG2|ENST00000381157|protein_coding|+|76N>76Y|31140A>T . 31177 C T missense|GYG2|ENST00000381157|protein_coding|+|88A>88V|31177C>T+31178G>T . 31177 C T missense|GYG2|ENST00000381157|protein_coding|+|88A>88V|31177C>T . 31178 G T @31177 . 31178 G T . synonymous|GYG2|ENST00000381157|protein_coding|+|88A|31178G>T bcftools-1.21/test/csq/ENST00000381157/haploid-diploid.vcf000066400000000000000000000011701467060157400224120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1 SAMPLE2 X 31140 . A T . . type=ENST00000381157:2777948-A-T GT 0|0 1 X 31177 . C T . . type=ENST00000381157:2777985-C-T GT 1|0 1 X 31178 . G T . . type=ENST00000381157:2777986-G-T GT 1 0|1 X 31180 . C T . . type=ENST00000381157:2777988-C-T GT . 0|1|1 bcftools-1.21/test/csq/ENST00000382647/000077500000000000000000000000001467060157400166565ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000382647/ENST00000382647.fa000066400000000000000000000060251467060157400210200ustar00rootroot00000000000000>5 5:1798480-1801500 GAGAATGAATGAACTAAGCTATTCGGAAGGTCTATTTTAATAGGAAAATGTTTTTTAGTT GGAACGTTTTGGAAATAAGATAACGCAATGTCTTCTATAGTTACTCATTTACACTGAAAC GTGATGGGTAACTTTTAGGGCGTTTGCTTCCAGTCACTTTCCCCTGACTCCTTGATGTGA TAATTCCTTCCATAAGATACAACCATTCTCCCAAGTGATGCGATGACGAGTATGTGCGTG ACTCTGGAGGGAAAGGGTCTACATCTGTCTCTGCTTGTGCCTCGGATGGGTTTTACAGTA GACGTACCACCGACCCCGCCTCTTCACCAGGTAACAGTCCTTGCAGCGCTTCTTAAGGAC AGTCTTGTTTTTGAACCCCAGCGCAGGCAGCAGATGGGGCAGGAGGCCGGGTGAGAGAAG TGAGCGCACTGCTGCCCCGGGTTCCACAGCCACGGGGGCTGCACCTCGAATGGATCCAAA TAGAAATGTGGAGAGGGCTCGAGGCTTCACCGTGTGACGACTGAGATAGAGCAGAGGGTT CACCATTTTCCTTATAAAAAGATTTGCCATGTTGTGGTGAATCTATGGGAGAGAGAAAAA AAGGAGTTATAGCTTCTCCTGCACTTCCACCTGCTCTTTAAGGCTTCCTTTTCTCTGTTT CACTGAGGCTTGGGAAGGCAGGGACCTCGGGGACTGAGGGTGTTCCCATACCAGCTGCAG CCTCGACCTGAGCTTGAACACTGCCTTAATCAGCCAAGTGTGCCAGGAGAATAAGGGGCA GTGGACGGTGGCTTCCTTCCCTTTCCCGCCTGCTGCAAGTGTAGGTGAGTGTGCAAAGCC CTGCGATGTTGAGGAGCCGCTCACTTGGCTGGGAGGGAGCTTAAACTTAGGCCGCATCCC TTTCCAAACAGACACCAGGTCAAGGACGGTTCAACTGATGAGCTCCTCCCTCCAACTCTT CCCAGACCCAGGGGCCCTCCCTCGGGCCAGTTTCGGGACAGGCCCCCGCTCCGGAAGAGC ACGGAACTCTGGCACCCCGGTCGCCCGCCCCTGCTTCCCCACGCGCCCCGGCCCTTAGGG TTCAGCGGCCCCGGCTGGGAAGAGCTGGGCCTGCAGGGCCCGGAGGACACTGCGGCACCG GAGCCGGCCCTGCGCGCGGGCTGTGAGGTCGCGTTCGGGAGCCGCCAGTTCTCCCGCCCC GGGGTCGCTGGACACCCCCTCCTGTCGCCAGGTCGGGCGCCCACGGTCGGACCCGCACCC CCCAACCCTGGCCCTCTGAGACCGCCAGGCCCCGGCCCACGCTCCTCTGACCGCAGCCCA CTCGGGGAGACACGCCCGAGGGTCCCAAGGTGGCCGGCCCCACCCTCTCGCAGCCCCCAC TCTCAAGACACCCGGGACCCCTGACCTGAGAAGACGGCTCCCTTACCCGGCCGCACGCTC TCACCCGGCGCCGACCCCTGCGTCTGCGCACTGGCACGCGGACGCTGCTGCCAGGAAGGA AGATGGCGGCGGGGGGGGGGGTCACGTGGCGTGCCCACGTCCAGTGCGGGGCGCAGAGAC GCAGCAGCGAGTGCGCAGGCGCTGGAGTGCGACGTATCACTCCCCGACTGCGCGCACTCT GCGGGCCACCGGGATCGTCGTGCTGTTTGGAGCGCTCTCGGGAAAAAAAATGCAAAAACC AGGAACGAAAATGGATATCCGCAACGAAAAAGAAATTACAACCACTTAGGCCTTAGAAAA AACTGGCAAATACCAATGTCAAAACAAACTGAGAAAGAGGACATGTTTTTAAGTGGACAG GAGAAATGTAAACAGGCTCCGGGAAACGAGTGGAGACGGGCAGTAGTTTCAACTGGTTAC GGCTGTTTTCCCCAACATTATGAAAAACTTCGGACATAGAGAAAAAGGGAAAGAACTGTA CGGTGAACACCCATATACTTGCCACCTAGATTCTACCCTTAGCTCGCTTATCCCTGCCTT TTCAGGTATCTACCCGTAACTCCATTCGCCTTCCTTTTTGTGTGTGTCCGGGTGAGTTGC AGACGTGGCTGCGTCCACTCCGCGCTCCCTGCAGGCCCCAACGCTTCATCGCAGCGCCCA CTTTTTCCACCTGACCCGGCGAACACCGGGCGGGCCGCTGGAGTTTATCAGCTCCAGGAC AAATCTGCCTCTGACCACCACGTTTGCTGGGACATCTTTGGGACCGGAGGTTTTCATGTG CATTCTTGTTTCTCATGCCTTTCCTCCTCTTTATCATCTTCCCCGCCACTCATCCATCTC TAGTGTTTTGTTCTTGGAGTCACGTGGTCCTCAGGCTCTGACCACAGCAAAAGAAAAGCT GGATGCTGGAGCTTAAGCTGGGATTTATACCCAAGTCAACTCTAAGCAAAACGGGCCTTT TTAGAGGCTGTATTTGCATGCTGTAAAATCAGTCGGTGTACTAGGCTTTGTTGCAGAAAT CCCCAATATACGTTTCCTCTGCGGCTCCCCGTAACCACACACAGGAACGCTTGCCTTGAA CGAGGAGAATGCACTTCCAGTCTCGTCTGCTAAGCAGTTGACTCCTTCACCCAATAATTT TGATATTTAAATGTCTCATGATTATCGGTTACCATAAGAATATAAACAATGTATTTTCAG TTTACATCCTCCCCTGCCTGTCCGCTAAATAAGAACCACTGGGTACTCCTAATCGCTGAA GGTTTCGCACACCATTGCCTGCCTCATCAGGGCCCTAGCTCTAGCCTGCGGCTGCAACTG CATGAGGCTGCACCTGCCGGCGCAACGGGGCCGCTTAACTTTTAGGCCATTGATGAAAAG TCAAACAAGCGCACAGTACTCGGTGTAATCAGGGGCATTTTTAGCGAGATACCTGGGATG AAAACGGGTGACCACCTGAATCAGAGAGCAGCTCCGGCGCACCCTCTGCCCCGACCCGCG CTCCCCGCCCCCAGGGCGAAATAAATACCGGGTGTTTGGCGCCGCCAGAAGCCGTGCGCA TGCGTTAGCGCTAAGCGGGAC bcftools-1.21/test/csq/ENST00000382647/ENST00000382647.fa.fai000066400000000000000000000000201467060157400215430ustar00rootroot000000000000005 3021 21 60 61 bcftools-1.21/test/csq/ENST00000382647/ENST00000382647.gff000066400000000000000000000022421467060157400211710ustar00rootroot000000000000005 ensembl_havana gene 21 3001 . - . ID=gene:ENSG00000171421;Name=MRPL36;biotype=protein_coding;description=mitochondrial ribosomal protein L36 [Source:HGNC Symbol%3BAcc:14490];gene_id=ENSG00000171421;logic_name=ensembl_havana_gene;version=8 5 ensembl_havana transcript 25 1473 . - . ID=transcript:ENST00000382647;Parent=gene:ENSG00000171421;Name=MRPL36-003;biotype=protein_coding;ccdsid=CCDS3865.1;havana_transcript=OTTHUMT00000365909;havana_version=2;tag=basic;transcript_id=ENST00000382647;version=7 5 havana three_prime_UTR 25 258 . - . Parent=transcript:ENST00000382647 5 havana exon 25 582 . - . Parent=transcript:ENST00000382647;Name=ENSE00003238927;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003238927;rank=2;version=1 5 havana CDS 259 570 . - 0 ID=CDS:ENSP00000372093;Parent=transcript:ENST00000382647;protein_id=ENSP00000372093 5 havana five_prime_UTR 571 582 . - . Parent=transcript:ENST00000382647 5 havana exon 1445 1473 . - . Parent=transcript:ENST00000382647;Name=ENSE00001492895;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001492895;rank=1;version=5 5 havana five_prime_UTR 1445 1473 . - . Parent=transcript:ENST00000382647 bcftools-1.21/test/csq/ENST00000382647/synon-splice-region-insert.txt000066400000000000000000000002351467060157400246250ustar00rootroot000000000000001443 A ACCCGGCCGCACGCTCTCA splice_donor|MRPL36|ENST00000382647|protein_coding 1443 A ACCCGGCCGCACGCTCTCA splice_donor|MRPL36|ENST00000382647|protein_coding bcftools-1.21/test/csq/ENST00000382647/synon-splice-region-insert.vcf000066400000000000000000000010131467060157400245570ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 5 1443 . A ACCCGGCCGCACGCTCTCA . . EXP=splice_donor|MRPL36|ENST00000382647|protein_coding;type=ENST00000382647:1799922-A-ACCCGGCCGCACGCTCTCA, should be synonymous splice region if seq were checked: ...GCTCTCAc|ccggcg bcftools-1.21/test/csq/ENST00000390520/000077500000000000000000000000001467060157400166435ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000390520/ENST00000390520.fa000066400000000000000000000002021467060157400207610ustar00rootroot00000000000000>14 14:22995792-22995894 CTGGGCCTTAAATCATTGTGTGATCAAAGCTGCAGGCAACAAGCTAACTTTTGGAGGAGG AACCAGGGTGCTAGTTAAACCAAGTGAGTACTGGGGCTTGACC bcftools-1.21/test/csq/ENST00000390520/ENST00000390520.fa.fai000066400000000000000000000000201467060157400215150ustar00rootroot0000000000000014 103 25 60 61 bcftools-1.21/test/csq/ENST00000390520/ENST00000390520.gff000066400000000000000000000013531467060157400211450ustar00rootroot0000000000000014 havana J_gene_segment 21 83 . + . ID=gene:ENSG00000211872;Name=TRAJ17;biotype=TR_J_gene;description=T cell receptor alpha joining 17 [Source:HGNC Symbol%3BAcc:12045];gene_id=ENSG00000211872;logic_name=havana_ig_gene;version=1 14 havana J_gene_segment 21 83 . + . ID=transcript:ENST00000390520;Parent=gene:ENSG00000211872;Name=TRAJ17-001;biotype=TR_J_gene;havana_transcript=OTTHUMT00000410981;havana_version=1;tag=basic;transcript_id=ENST00000390520;version=1 14 havana exon 21 83 . + . Parent=transcript:ENST00000390520;Name=ENSE00001508149;constitutive=1;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001508149;rank=1;version=1 14 havana CDS 21 83 . + 2 ID=CDS:ENSP00000451250;Parent=transcript:ENST00000390520;protein_id=ENSP00000451250 bcftools-1.21/test/csq/ENST00000390520/deletion-overlap.txt000066400000000000000000000001571467060157400226600ustar00rootroot0000000000000081 CAAGT C coding_sequence|TRAJ17|ENST00000390520|TR_J 81 CAAGT C coding_sequence|TRAJ17|ENST00000390520|TR_J bcftools-1.21/test/csq/ENST00000390520/deletion-overlap.vcf000066400000000000000000000006351467060157400226200ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 14 81 . CAAGT C . . EXP=coding_sequence|TRAJ17|ENST00000390520|TR_J;type=ENST00000390520:22995872-CAAGT-C bcftools-1.21/test/csq/ENST00000400151/000077500000000000000000000000001467060157400166335ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000400151/ENST00000400151.fa000066400000000000000000000710621467060157400207550ustar00rootroot00000000000000>4 4:699553-728288 AGCCCAGACGCACACCGCGCATGCTCCGAGCGCGGCGCCCCCGACGCGGCGCTCGGCTCG GCTCGGGCATTTCCGCCTCTTTGTTTTAAACTCCGGACGGGCTTTTTTCTCCTCCTCTTG GGGGGGACCCAGAGGGAGCGGCGCCCCCTCCCCCCTCCGGCGCGGACCCCGCGTGCGCCT TGCTCGCCCGCAGCCCCGAGACCGCAGGTCAGTGAGTCCGCCCCGCCTGGCCTGGGCCCT CGGCGCCCGCTCCTCAGGCTGCGGCCTCGGCCCGTGTCCGGCCCGGAAGGCTCCGAACCC CGGGCCCGCGCTCCGTCGTCCCCGTCGGCCTGGCCCGGGAAGCCCTTGGCAGGCCCGGGA GGGCCGGCACCCCAGCCCAGTCAGGACTCCGGGAGGTCGAAGACCCCAGCCCAGGCAGGA CTCCGGGAGGGCCAAGAGCCCAGCCCAGGCAGGACCCCGGGAGGGCTGGGACTCCAGCCT AGGCAGGACGCAGGGAGGGCAAGACCCCAGCCCAGGCAGGACTCCGGGAGGTCGAAGACC CCAGCCCAGGCAGGACCCAGGGAGGGCTGGGACAGCAGCCCAGGCAGGACGCAGGGAGGG CAAGACCCCAGTCCAGGCAGGACGCAGGGAGGGCAAGACCCCAGCCCAGGCAGGACTCCG GGAGGTCGAAGACCCCAGCCCAGGCAGGACCCAGGGAGGGCAAAGACCCCAGAACAGGGA GGGCCAAGACCCCAGACCAGGCAGGACCCCGGGAGGGCCAAGACCCCAGACCAGGCAGGA CCCAGGGAGGGCGAAGACCCCAGCCCAGGCAGGACCGCGGGAGGGCAGGGACCCCAGACC AGGCAGGACCCCGGGAGGGCCAAGACCCCAGACCAGGCAGGACCCAGGGAGGGCGAAGAC CCCAGCCCAGGCAGGACCGCGGGAGGGCAGGGACCCCAGACCAGGCAGGACCCTGGGAAG GTCGCGACCCCAGCCCAGGCAGGACCCAGGGAGGGCGAAGACCCCAGACCAGGCAGGACC CAGGTGAGGGCGAAGACCCCAGCCCAGGCAGGACCGCGGGAGGGCAGGGACCCCAGACCA GGCAGGACCCTGGGAAGGTCGCGACCCCAGCCCAGGCAGGACCCAGGGAGGGCGAAGACC CCAGACCAGGCAGGACCCAGGTGAGGGCAAAGACCCCAGCCCAGGCAGGACCGCGGGAGG GTAGGGACCCCAGCCCAGGCAGGACCCTGGGAAGGTCGCGACCCCAGCCCAGGCAGGACC CCGGGAGGGCTGGGTCTTCAGACCAGGCAGGACCTGAAGAGAGTTGGGCTCTGGGATTGC ACAGGACCCCCAGAGTGCTAGGACACAATGACACATCATCCAGGAGGGTCTGACCCTGGG ACAGGTCACCGAGAAGGGCTGGGACCCCAAGATGGGTCACCAAGGAGGGTCGGACCTGGC CACCTGGCAGGGCCCGGGGGGGCTAGGACCCTGGGAAGAATCACGGAGGAGGGCCAGACG TAGGGACCAGGCAGAATCCAAAGAATGCCAGGACCCCAGAATAGATCCCCCAGGAAGGTC CTGCCTTAAAGTGGGTCACAGACGAGGGCCAGGACCCCATGACCATAATTCAGGAGGACC TGACCCTGGAGCAGTCTTGTGAGTCCTGTGAGCACTGCTGGGACCCTGAGACTGCCCCGT CTCCCCCGGGACCCTGAGACAGCCCTGTTTTCCCCTGGGGGCCGGGACCCTGGGACAGCC TGTTTTCACCCGGGGGCCGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGTCGGGACC CTGGGACAGCTCTGTTTTCCCCTGGGGGTCGGGACTCTGGGACAGCTCTGTTTTCCCCTG GGGGTCGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGTCGGGACCCTGGGACAGCTC TGTTTTCCCCTGGGGGCCGGGACCCTGAGACAGCTCTGTTTTCACCTGGGGGCCGGGACC CTGAGACAGCTCTGTTTTCACCTGGGGGCCGGGACCCTGGGACAGCTCTGTTTTCCCCTG GGGGCCGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGTCGGGACCCTGGGACAGCCC TGTTTTCACCTGGGGGTCGGGACCCTGAGACAGCCCTGTTTTCCCCTGGGGGTCGGGACC CTGGGACAGCCCTGTTTTCCCCTGGGGGCCGGGACCCTGGGACAGCCCTGTTTTCCCCTG GGGGTCGGGACCCTGGGACAGCCCTGTTTTCCCCTGGGGGCCGGGACCCTGGGACAGCCC TGTTTTCACCTGGGGGCCGGGACCCTGGGACAGCCCTGTTTTCACCTGGGGGCCGGGACC CTGAGACAGCCCTGTTTTCTCCCAGGGCCCGGCACCCTGAGACTGGACAGTGAGAAGGGC TCATGACATGGACAGGCTTCTAGATGACCAGGACCTCAAACGGGGTCACTTAGGGTCGGG ACACTGGTGTGGACTGGGAAGAAGGCTAGGCTCTCAAAGAGGACCTGATGAGAGCTGGAA CTTCCAGACAGGTCCTCAGAGGGCTGGGACTCCTGAACAAGTCACTGAGGAGCATGTAGG CCCCAAGACTGGACTGTAAGGAGTACTGGGACCCTCGGGGGGGAATCCAGCAGTGTCCTG AATCTGCCCAGTCCACTCAGCTGGATGCACCTGCTGTGAAGGCCAGGCATCTGGCATCCT GGTACCCGAGGCCCTTTCCATGAGACCCTGGGCCAGCCCCACAGCCCCTGCACATGAACC GCCTAGGTGATACCTGGGGTAGGTATGAGGCAGGGGCCTCAGGGTTCCAGGAGCTCCCAG CCCACAGGCTCCACACCTCAGGCTGGCACTGCACCCTCCCACTCAGCCCCTCGTCCGGGG CTGCTGTCCTGTCCTTGCCTTGGCTGTGGTCCGTGTCCAGCACCTTCAACCCCTCCTGCC CCTCTCCCCATCTTCAAGGTCATGTGAGTGCCCCACTTCCTCAGTGTAGAGGCGTTTCCA GTGTCCGGGAGACTTGGAGGAGGGGTGGGGTCTGAGCTGGGATGTGGACTCCTGGGCATA TTTTGGGGACAGTTGGTCCAAGTCAGGAAAGTTGGAGCAGGCAAGGCTATTTCCCACTCC CTCTCTAGTAAGGGAAGGAATTAAAGGATCCTGGTGGTGATCGGGCTGGGGACGGGGGTT GGTTTATTTCTCTGAAACCTTTGAATCAGCCTTTTATCAAAAACTTGTGGGTGTTTTCCT TTAATTTGGAAGTGGTAATGAAAAAGTGGGGTGCATGAGGTATTCAGAAGCGAGCGGTCT ATGCTGTCCTTTGACTAGGGAAGGGTTGTCTAGTGACATCTTGTCAGGGGTGTTTCCAGA GGGTGGTCATCCCAGGAACCCTGCTCCCAGAGGGTGCCGTGTGGCTGCTTGGTGTGCCGT ACATTCCCCAAAAGAGTGAATGATGCATGAACGAATGAAAGGCAAGAGTGAATGATGCAT GAACAAATGAATGAAAGGCAAGAGTGAATGATGCATGAACAAATGAATGAAAGGCAAGAG TGAATGATGCATGAACAAATGAATGAAAGGCAAGAGTGAATGATGCATGAACAAATGAAT GAAAGGCAAGAGTGAATGATGCATGAACACATGAATGAAAGGCAAGAGTGAATGATGCAT GAACAAATGAATGAAAGGCAAGAGTGAATGATCCATGAGCAAATGAATGAAAGGCAAGCG TGAATGATCCATGAACAAATGAATGAAAGGCAAGAGTGAATGATGTATGAACAAATGAAT GAAAGGCAAGAGTGAGTGATGCATGAACAAATGAATGAAAGGCAGGGCCGCTCTTCAGAG ACATCCCCTCGGATTAGGCGTGCGGGCTTGCCTGGAAGTTGGGCAGTACAATGAGGTGTA ACCCTAAAACTCTGAGCTATCTAGACTCCCAAGAGAGACACTGAATTGGATGGTTCGGGA TTTCATCTTTGCCACAGCTTCACTTCTTGGTTACTTAGGAGAAAACCGTGTTAGGTTTTC AGCTTAACATTTCAGGGTACTCAGTGTCAGCCACGTCGTGTCCCTGCGTGGTCAGCCTGG ACCTAGAAGCTCTTACTCGCCCAGTGTAACCGCCAGGGACCTTTTTACTCAACACTTCCT TCTGATTTGCTCTTTTGACATATCCTTTACTGTTTTTTAAACTTCATTTGCTTTGTGAAA TTGTGGAAGAGGCTTGTGAAGCTGAGTGTTCAGGTTTGTTTGGCTCTGTACTGTCTGGTT CCCAGGCTTTTAGAGGTGTGTTTTAGAGGTGTTTTTAGGCCGTGCTGAGTGGTTGTATTA TTTATATATTGCTGTGTGGCAGATTACCCCAGAACCCCTGCCTTAAACCAACAGTCCGAT GATAACTTACTGTTTCTGTGGGTTGGGAGACCAGGTGGGCTCTGGCTCAGGGACCTCCCA TCTGGGGTTGTGTCTCCTCTGAAGGCTGGACTGGGGAGGGTCCGCAGCCAGGCTGTGTCA CGTGACTGTGGGCTGGAGACCTCAGTTCCTTTCTCTATAGGGCAGCTCCGAGGGAGCCCA TGCCTAGCCAGAGAGGGACAGGAAGGACGTCCCAGTGTTTGTGGAGTGACATTCTACCAC TTTTGCCAAGAGTCATTCGGCCCCTACACACTTGAGGGGAGGGGACTCCAAAACGGTGAG CATACGATGGGCAGGTGGGGTCACTGGAACACTTAAAGCCTGCCCAGCACAGCGGTGCTG TGAGCCTGGCACCTCTCAGGGCACTGGAGAGACATCCCGTAAGTAAATCAGCGATTGCGT GTGGAGTGACGTGTTAAGATGAGGATGTGACTGTTCAGCTGTCTCTTTAATTGGTGTGGG TTTCTCCGATGTCACCGTCATGATTGAGATATTTGTGATACGTAAAAGAAGATAAATTAC AGATAGAAAAGATTCTTAGGAATTAACTTGCAATTTGGCATACCAGTAGCAAGCCAAAAG ACCCCCCCACAAATTAAATTACAAGGTGTGTGTCACTGATGTCAAATCCTTCCCAACAGC TTCAAGTGCAAGGATTTTTGCTGTTCCCAGAGTCCCCTCATTTTCTTCCTGCCAGTGATT TTGCTCCAGAAATTATCAACCGACTTCTGTTAAGTTTTCCTAAACCATTTTAAATATATG GGGGAAATGTTTTTACCAGTTACAGTAGACCTTGCGCTTGCAGTTATTTGTGACTTCATA AAAATGCCGTAGGAGACGTGAGACCTTGACCACACTGGACATTTGACCGGTGTGAGGACT TAGCTCCAGGGTCCAGGCACTACTGTGAGCCAGAGCCTCTGCTCCTAGCCCACACCCTCC ACTGCACAGGGAGCCGGACCCCATGCCTCCTTCCGGTTCTGGGCTGGAGCTAGGGCCGGG AAGGGGGCCTGTTCTGGACTCTGGAGACCTCAGCCGCCCCTCCCACCATGCCGCACTCTC TAGACTACAGCGGCTCTGTGGCAAAATCGAGGAGCTGCAGGGTGCGGCAGGGGCCCTTTG CCGTGGGCTAGAATTCTTTACTTGGGTTTTTTTATTTGGATTATAAAGTGAGTCTTGTTT TGGTGTATGCTGTTACTCTTTATTAAATGGCAGGATTTATTTTGTTTGCAGCCTTATTTT TGGTTAATGGTTAGAATTGAAGTTGAAAATGTAATTTTTCTTTTTTTTTTCTTTTTTTTT TTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCCGGACTGCGGACTGCAGTGGCGCAAT CTCGGCTCACTGCAAGCTCCGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCG AGTAGCTGGGACTACAGGCGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAG AGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCC GCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCGAAAATG TAATTTTTCTACAGAATTAGGCAGGCGTGTGTAATTTTTCAACAAAAATTAGCCAGGCAT GGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAAC CCGGGAAGCGGAGTTTGCAGTGATCTGAGATTGCACTCCAGACTGGGCGAAGAGTGAGAC TCTGTCTGAAAAAAAAATAAAAAGTAAAAAAAAAAAGAAAAGAAAATGTAATTTTTCTTT TACCATTGAAATATAGTGAGGTTTAGGGACAGTTTCCTATTGTTTATCTATTTTTTATTA TGATACTTGCTGTTAATATAGCAAAAATATGGTACAATTCATTGTGCTTCAAAAATTGAA ATTATTTTTAATTTCATACATTGATAGTTTATCACTGAATTTTAAAAATGTGAGGCCTTA AGAAAAACAAAACAAAACTATCTTTCCAGATCTGCCACGTTTCTCCCGACAGAACTGAAT TATGCAAATGCCAAAATGACAAAGAACAATAGTGAATGTTGCCTAGGTGCATTTTTGTAG AATTATCCACTGAGTTAAGCAAAACTCCCATTGACAGGAACTCACACTCTAGAAAATATA GTCCTTCAACCTATTGTTATATTGACTTGCTTTTTTTTAAGATAAACTCTAATATTCGTG TTTGTTTGTTTGTTTTTGTTTTTTGTTTGTTTGTTTGTTTTGAGATGGAGTTTTGCTCTT GTAGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCTGGT TCAAGTGATTCTCCTGCCTCAGCTCCCTAAGTAGCTGGGATTACAGGCGCCTGCCACCAT GCCCGGCTAAGTTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGG TCTCAAACTCCTGACCTCATGACCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAG GCGTGAGCCACCGCGCCCGGCCAATAAACTCTAATATTTAGGTGCATTTAGAGAGTGGAT TTGTTGGCTTGGTTTCTTTTTTCTTTTTTTCAAATTCATTGATATTTGCTGGGCTTTGCT ACATTAACAGCAAATTCCAGATGTTTAATGAGAAATAGATGCAAAGAGGGGAAATCTGTC TGCAGACTTCCTTGAAACTCCCTCTAATCAGTGGGTCCCGTTGGCCTTGTGGGTCTTATG GGGGCTGTGAGCCTCGTGGGAGCTGTGGGCCTCATGGGGGCTGTATGGCCTTGTTGGGGG CCTGTGGGGCCTGTGGGCCCTGTGGGGGGCTGTGTACCTCCTGGGGGCTGTGGCCAAGTG GGTCCTATGTTCTTCGTGGGTCCTGTGTGGTCTGGTGGGGGCTGTGGCCTCGTGGGAGCT GTGGCTTTGTGAGTCCTGTGTGGCGTCATGGGGGCTGTGGCCTTGTGGGTCCTGTGTGGC CTGGTGGGGGCTGTGGCCTTGTGGGTCCTGTGTGGCCTGGTGGGGGCTGTGGCTTCATGG GTCCTGTGTGGTCTGGTGGGGGCTGTGGCCTCATGGGGGCTGTAGCCTTGTGGGTCCTGT GTGGCCTGGTGGGGGCTGTGGCTTTGTGGGTCCTGTGTGTCTCATGGGAGCCGTGGCCTT GTGGGTCCTGTGTGGCCTTGTGGGGGCTGTGGCCTCGTGGGGGCTGTGGCCTCATGGGTC TTGTGTGCCTTGTGGGGGCTATGGCCTCATGGGTCCTGTGTGGCCTGGTGGGGGCTGTGG CCTTGTGGGTCCTGTGTGGCCTCATGGGTCCTGTGTGGCCTCGTCAGGGCTGTGGCCTCA TGGATCCTGTGTGGCCTCGTGGGGGGCTATGACTTTGTGCCTGTGTCTCCTGTCTGGGTC TTGTGAGCTGTCACATTTCCAGGTTCTTGATCAGGGCGTGGCCCGTATTAGATGCTCAAT AAACAGTAACCGGAAGCTGATCCTCATGGATGCTGTGTGGAGCTGTTCTGAGGCGGCATG AGTATGAACTTGTTGGATTCCTGATGCCGCCCAGGAATCAGACCGTAAAAGCTGTGCTTA TTTCGCAGTGTGAGCCTGGCACAGCAGAGGGCGCACAGGGCAGGCATCATTGGAATGTGG GGGCCACGAGGGCTCACCTTAAAATTTTTTAAATGTTAAGTGATTTTAATTTACTTTTTT ACCCAAGTTTTTGTTAAGAAAAAAAATCGCAATACAGAAAAATGGAGAAAATTATACAGT GAGCACTTGCTGTGGTCCGAACGTCTGTGTCCCCCAGAATCCATGGGGGACCCTAACCCC CAAGGTGTCAGTGTCAGGCGTGGGGCCCTCGGAAGGCTCTGCCCTGATGACAGGACCAGC GCCCTTTCTGTCATTTGAGGACACGAGAGAAGGCACTGCCTGTGAGGACTCTGACCCCAC CAGCCCCCAAATCTGCGAGCGCCTTGATTCTGGACTCCCAGCCTGCAGAACTGAGAGGTG CGTTCTGTGGTTTGTCAGCTGCTCGGCCTAAGGTGCTTCGGTCGCAGCCGCCTGAACAGA CCAGGACGGCACCCTCTACTGCCCAGACCCACTCGTGGCCGTTCGGCCGCATTTGCTTCC TCTCCTTCTCTCAGTACATCCTGGACTCACCTGTGAGCGGCTCCGGACAGGAGCCTTGCT GGGAAGGTGAGTCCCACCTGAGAGCAAGAACTAGGGGAGGCCCCCACACCGCTACAACCC CACTGTGACCCTAGGACGGTGGCACCTACTTCACGGCGTTACCTGATTTTCAGGCCGCCT TACCTCTTCCCAGCTGTCTTGAGAATGTCTCCATGTTTTCCTGAACCAGAGTCAGCCAGG GCCTGTCCTTGCCCTGGAGGTCCTGGCCCTTCTGACCATGCCAGGTGAGACCCCCTGGCG TTGGAGGTCTTGTCTCCCTGTCCGTGGACCGGGCTCGCATCCTTCCCACCCCACTGCCTT CTGCCAGGCCAGCGGAGACATAGGCCCTGACGTCCTCTTCAGTCTCAGCTGGAGAAAGCT GCCCTGGAGGGACTCTTCTCACTAGGTCACGCAAACCTGGGCACTCCCGATTTTGAGGTA GCTTATTTGGGACCTTAATTACAGCTTCAAAAGTCCCTTTACAGCAGTCCATGGGTCAGT ATGTCAGTAACAGAACTGGGCGTCGGTTCTGGGACCCTGTAGACACTGAGGGTGAGAACT GGGTGTCGGTGCTGGGACGCTGTAGACGCTGTGAGTGTGAGAACTGGGTGTCGGTGCTGG GACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGA GTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACTCTGTGAGTGTGAGAACTGGGT GTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCT GTAGACACTGCGAGTGTGAGAACTGGGTGTTGGTGCTGGGACCCTGTAGACACTGAGTGT GAGAACTGGGTGTCGGTGCTGGGACCCTGTAGACACTCAATGTGAGAACTGGGAGTCGGT GCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCTTGTAGAC ACTGTGAGTGTGAGAACCGGGCATCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGCAC TGGGCGTCGGTGCTGGGACCCTGTAGACACTGTGAGTGTGAGAACTGGGCGTCTGTGCTG GGACCCTATAGACACTGAGTGGGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTG AGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGTGAGTGTGAGAACTGGG TGTCGGTGCTGGGACCCTGTAGACACTTAGTGTGAGAACTGGGCGTGGGTGCTGGGACCC TCTAGACACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTG TGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGTGAGTGTGAGAACTGGGTGTC GGTGCTGGGACCCTGTAGACACTTAGTGTGAGAACTGGGCGTGGGTGCTGGGACCCTCTA GACACTGTGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGAGGGTGAG AACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGGGTGAGAACTGGGCGTCGGTGCT GGGACCCTGAAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACT GAGTGTGAGAACTGGGCGTCGGTGCTGGAACCCTGTAGACACTGTGAGTGTGAGAACCGG GCATCGGTGCTGGGACCCTGTAGACACTGAGGGTGAGAACTGGGTGTCAGTGCTGGGACC CTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGAACCCTGTAGACACTTAGTGT GAGAACTGGGCGTGGGTGCTGGGACCCTCTAGACACTGTGAGTGTGAGAACTGGGCGTCG GTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTGG ACACTGCGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTGGACACTGTGAGTGTGA GAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGCGTCGGTGC TGGGACCCTGTGGACACTGCGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGAC ACTGCGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTGGACACTGCGAGTGTGAGA ACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGGGTGTCGGTGCTG GGACCCTGTAGACACTGAGTGTGAGAACTGGGTGTCGGTGCTGGGACCCTGTAGACACTG TGTGAGAACTGGGCGTCGGTGCTGGGACCCTGAAGACACTGAGTGTGAGAACTGGGCGTC GGTGCTGGGACCCTGTAGATACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTG TAGATACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTCTAGACACTGTGAGTG TGAGAACTGGGCGTCGGTGCTGGGCCCCTGTGGACACTGCGAGTGTGAGAACTGGGCGTG GGTGCTGGGACCCTGTAGACACTGTGAGTGTGAGAACTGGGCGTCGGTGCTGGGACCCTG TAGACACTGAGGGTGAGAACTGGGCGTCTGTGCTGGGACCCTGTAGACACTGAGGGTGAG AACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGAGCGTCGGTGCT GGGACCCTGTAGACACTGAATGTGAGAACTGAGCGTCGGTGCTGGGACCCTGTAGACACT GAATGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGAGAACTGAGC GTCGGTGCTGGGACCCTGTAGACACTGAATGTGAGAACTGAGCGTCGGTGCTGGGACCCT GTAGACACTGAATGTGAGAACTGGGCGTCGGTGCTGGGACCCTGTAGACACTGAGTGTGA GAACTGGGTGTCAGTGCTGGGACCCTGTGGACACTGTGAGTGTGTGCTTACTTTTTTTTT CAGTCTTGCTTTGTCACTCAGACTGGAGTGCAGTGGCAGGGTCTCGGCTCACTGTAACCT CCACTTCCTGAGTTCAAGGGATTCTCCCGTCTCAGCCTCCTGAGTAGCTGGGACTGCAGG TGCTTCCCACCACACCCAGCTAATTTTTGTATTTATATTAGCGACGGGGTTTCACTGTAT TGGCCAAGCTGCTCTCAAGCCCCTGACCTCGTGATCTGCCCACCTTGGCCTTGCAAAGTG CTGGGATTACAAGTGTGAGCCACCGCGCCCGGCTGTGTGTGCTTACTTTCAAACAAGGTA GTCTCTGCAGCATACTGAGATGACATTGAGAAGAGGCTTGATAAGGTGCAGGAGGGCGTG TTCTGGGCACAGGGCGCCCTGAGCGAGAGGGCCGAGAATGTCCTGCGGTGATTGAGGAGT CCACGCGGCAGGGGCAGAGGGAGAGGCAAAGGCAGAGGGAGGTGTGGGCTGTTGGCAGGG CCAGGGCCTGACCTCGATGGCCCTGAGGAGCCTCTGCGTCCACTCAGGCTTGTGTGTTCG GGAATCCCGTGGGTGCTGCGTTGAGGTCAGTGGGGCCTGGTGTGGCAGAGGCGAGGGTGC TGTGTGGGTGCCGCGTGTCCTTCAAGGCACAGCAGATTGGTTTCTAGGGGGGCCCAGTGT GAGGGAGGCGCAGGTGGCTCAGAGGTGTCTGGGGCTCCCTGGGGTGCAAGGCTGTCAGAG GAGGTCAGGGCAGGGAAGTCCTGATGGACGTGCCGGCCGCCCACTGACGTGCAGCCGTCA GACGTCTGGATGGGAGTTCAAAGCAGGGTTGGGCCAGAGGTGCCTGGAGAGGAAACGTGG AGTCGGGGGGTCTGTGGGGTAGCCCCGGGGGCGGCGCTGGGGGCCGGACTGCTGAAGCGC CCCCGAGCTCCCTGGGTATAACCTGCCTGGGCCTCCTGGACAGCTGCAGGCCTGCGGGGC CTGGGTTGAGGGGGATGTCACTGAGCTACACTCTGAGGCTGGTAGTGACTCTCATCTGGG GTCCCACCTTAGTGAATGTACCTTAGGTCTTTGTATGAACGCAAATATTTGTATAAACAC TTAATTTAAAAAATGAGAGCTGATGTGCGCCTGTAATCCCAGCTACTGAGAAATGTCAGC CCAGCAGTGAGGCCTGTCCAGTCTCAGCCCTGTCCGTGTGAGTGCTGTGCTCTGTGTGTG GCCCCCACAGTGCCACGGTCCACGGAGGTGGGGTCGGCTGGCTCTGGCTGGGAGTTGGGG GCCCAGTTGCTCTAATGCAGGCAACACCCTGAGTGGGGCTGGGAGTCAAGGACCAGGCTG GGGGCTCGATGTCACAGGTGTGGGCAGGAGCCCATGGCCCTCTGAGAGCTTTGTGGCCAC GGTAGGGGCTGGGCCATGGGGGAGGCAACTTTACTGCCTGGGGTCAGTTCCTGCCTGGCC AGAGATGGAGCAGGGATGCTTACTGTCTTTCGAGTCATGGACCCTTTTGAGAATTAAATT CAAAGCGCTGTCATGTTGTAGCATTGTTTTTCATTTTCTTTTTTTTCTTTTTTCTTTTTT TAATTTTTTGAGTTAGAGTCTTGTGCTGTCACCCAGACTGGAGTGTAATGGCACTATCTT GGCTCATTGCAACCTCTGCTATACAGGTTCAAGCATTTCTCCTGCCTCAGGCTCCTGAGT AGCTGGGACTACAGGCACGTGCCACCATGCCCGGCTATTTTTTGTATTTTTAGTAGAGAC GGTGTTTCACCATGTTGGTCAGGCTGGTGTCGAACTCCTGACCTTGTGATCTGCCTGCCT GGGCCTCCCAGAGTGCTGGGATTACAGGTGTGAGCCACCTCACCCGGCTGTTTTTCATTT TCTTAAAAAAACTTTTAGGGTGACATAGCTGTGCAGAGAACCATGTAAAGTTCCGTTTTC CTCCTAACCTGGTCGTCTCCAGCGGGAAGGAACAGAGAGTGCTTGGTGTGGTTCTGTGTG TCCGCACGAGGTTGATGAGAACCCTCGGTGCCTGGACTGTCTTCTCACCAGGCGCAGCTC AGGAACATGGTGGTGCCGGAGAGTGGTTTGTGTCTGTTCCTCCCTGGCTGCTGTGAGCCG CCCCCCCAGGTCCTGTGTCCTCCGCGCGGGTTGGCGAGGGAGCTGTGTGTGTCTGTGGTG CAGCTGCAATGCGGGGTCCCGTCAGGGAACAGGAGCGAGGCGTTTACGCCATAAGGAGGT GGAGAAGGGATGGTGTGTGAGTTTGGCAGGTGCTGAGGGCTACAGTGGAGCTGGAGGGGC AGGACGGTGCAGGGCGGTGCAGGCAGGGTGTTTGGGGTCAGGCCAGCTGTGGAAAGGCCA CAGGTGAACCAGGTGCGGAGACAAAGAGCTGGAGGCATCCGGTGGTCTGGCTGGGCCTCA TCCGTGTCCTGCCGCTGCTGCAGTGATGCCAGGGGCATGGAAGGGACCCTAGCCCAGCTC CTCCCTTGGCAGTCGGAGCGTCGGGGCCGCATTATAGAGGGAGGGACTCTCCGGACGATG GGAACGAGAGTCCATTGGGATCGTAGCTGTGGTGCGGTTCACAGCGTTGTGAACAGCTAA TGTTGGGCTGGGGGCATCTGTGGGGCCAGTTGCAGCAGTTTGGTCATTTTTGTGTGAAAA TAAATGAAAACAGGTTTTGCAGAGCCCGTTGGTGAAGGCAGGGGTGCCTCTGGCATCGAC TGGATGGCCTTTCCCTCCTGAGTGACAGCCCTGGACGTGCTGTCGCCTCATGAGGACGCC GATGTGGCCCTGCTGCCGGAGTATGCCAAGCACGAGGGGCCAGGTGGCACACAGCACCTG TGTGCCGCTGGGGAGGGTGACCGCGGGAGGAGCGCCCGTGCATCGCTGCAGAGGGTGACT GCGGGAGGAGTGCCCGCCCATGCATCGCTGGGGAGGGTGACTGCGGGAGGAGCGCCTGTG CATCGCTGTGGAGGGTGACTGTGCAGGAGGACAGAGTGCCACAAGGGAGAGCAGCAGAGT GGTTTCAGCTCCGGGAGGTGGGGCTGCCCGTCCAGAGAGGTGCAGGGTCTCTTGTCAGGT GGACAGGGGCTGGCCCACCCGTGAGTGGGTAGGGCCTCCTGCCAGGGAGCCTTGTGCATG GCTGGGAGGACGGCAAGGCTGATGTGGACGCAGCCCCGACGTGAACAGGACCCCACGTGG ACGGGCAGTGACGTGCGTGTGGACCCGGGGTGGACGGGCGGTGACGTGCGTGTGGACCCG GGGTGGACGGGCGGTGACGTGCGTGTGGACCCGGGGTGGACGGGCGGTGACGTGCGTGTG GACCCGGCGTGGACGGGCGGTGACGTGCGTGTGGACCCGGCGTGGACGCAGCCCCGACGT GAATGGATGTGGTTCCGACGTGACTGCGCTGGCATGGGAAGCAGAGGGTGAGGCTCGGCT CTGCTGTCAGGAGGACATGTCAGACTTCTGTCTCTAAGATACTGCTCAGACTTGTGTGGA GGGTGAATTAGTGCGAGGGCGGCTTGGAGAAGCCTGTCCTGGGCGGGTTTCACCACTTGG ACGGGAGCTCTGGCATGGTCCAGGGAGTGGCCGAGGACAGCAAGGAGGAGATGACCCCAT GGGCAAGCAGGAGCTCAGATGGGAGGCATGGAGCAGACGGGACTCCACGTGGCACCACCC CTCCCACCTGGGCTGGGCACCCATGAGGCTGAGGACCCTGGGGAGGGAACGCTGCTTGTC GGGCGGTGGTGACGATTTCATGGATGTTTGTGAAACCAACCTCACTGCCCCATTACAACA GTGCGGGCCCTGATTCTCATGGTTCCCCAGTGAGGCTGTTCCACGGTGGCACAGGACACG CCTGCAGCTTTGTGCCTGTGAATCTCAGGAGCTGTTTTCTGGAAAGTTCCATAACTCAGC AAAACTGACTCACAAACAACAGAAACTTCAAGGCTGTCCTAAGATATGGGTGGCAGAAGA AAATGTGCCCCAGGCATGGGCTTGTGATGCCGGCTCTTCCTCCTGGCAGAGCTCCCCAGA GGAAGGCTGGGCTGGGCAGTCAGCCAGACGGGAAAGGGGGCTGAGGCGTCCAGGCTGCAG AGGGTGCCGGGGTGGAGAGCGGAAGAGAGAGGGAGTCGGTGCCTTAGGAGGCTGCGGGCG AGGCGAGGGCAGAGTGCACTCGCTGGGGGTCACCCTGCCCCCCAGGACTCCTTTCACAGG ACAGAGAAGCTCCTGGTGAGCGGGGCTGCTGAACGCAGGCCCCAGGGCCTGTAGGACCCT TAGGGAGACGGGTGGCTCTGCGTGTGGGTGTGGAGAGAGGCCTGTGGGAGACGGATGGAT GGGTGTCTCTGTGTATGGGCATGGGGAGGGGCCTGTGGGAGGTGGATGGGTTGGGTGGCT CTGTGTATGGGCATGGGGAGGGGCCTGTGGGAGGTGGGTGGATGGGTGTCTCTGCATGTG GGTGTGGAAAGAGGCCTGTGGGAGACTGGTGGATGGGTGGCTCTGCGTGTGGGCGTGGAG AGAGGCCTGTGGGAGGTGGGTGGACATGTGTCGCTGCATGTGGGTGTGGGGAGAGGCCTG TGGGAGGTGGATGGGTTGGGTGGCTCTGTGTGTGGGCGTGGAGAGGCCCGTGGCAGCTCC TTCGTTGCAGAAACCGCATCGGAGCACATCGCGTAGTGCAGGACACACGGGGCGTGGGAC GGTGTCTGTGTGAGAGCAGCATCTGTGTGTATGCAGTGTTATCTAAGGACACACCCACAG ACACGGACACGTCCTTACGCAGAGAACAGCCGCTGCCTCTTAGTGTTCAGGATGATACGT TTTTCCTTAATATCATCCTTCGCTTTGCACATCATACTGAATACGTGTGTATGTGACTTT TACTGCAAAACAAAACAAAAAGCAGAAGCTACTGTGTTATCCAGACGGCTGTGTGCTGCA GGCGCGACTCAGAACAGCAGCTCCTCCCAGCATCCCGCAGCTAAATGACAGGAGCTGGAG GCTGCCCCAGGCAGCGGCGTGGCTGGCGTGCGGAGTGTTTTGGGGGTGTCTGAGCTGGGT GGAGAGGAAGGCATATGTCACACTGAGGCATCAGAGACACATCCATTCACGTCGGGGCTG TGTCCGCGCCGGGTCCACACTCAGTCATCGCCCGTCCGCGCCGGGTCCACACTCAGTCAT CGCCCGTCCGCGCCGGGTCCACACTCGCGTCATCGCCCGTCCGCGCCGGGTCCACACTCA GTCATCGCCGTCCGCGCCGGGTCCACACTCGCGTCATCACCTGTCTGCGCTGGGTCCACA CTCGCGTCATCACCTGTCTGCGCTGGGTCCACACTCGCGTCATCGCCCACCCACGCCGGG TCCACACTCGCGACATCGCCATCCACGCCGGGTCCACACTCGCGTCATCGCCATCCACGC CGGGTCCACACTCGCGACATCGCCATCCACGCCGGGTCCACACTCGCGACATCGCCATCC ACGCCGGGTCCACACTCGCGTCATCGCCATCCACGCCGGGTCCACACTCGCGTCATCGCC ATCCACGCCGGGTCCACACTCGCGACATCGCCCGCCCGCGCCGGGTCCACACTCAGTCAT CGCCCGTCCGTGCCGGGTCCACATTCGCGTCATCGCCATCCACGCCGGGTCCACACTCAC GTCATCGCCATCCACGCCGGGTCCACACTCGCGTCATCGCCCACCCGCGCCGGGTCCACA CTCGCGTCATCGCCGTCCGTGCCGGGTCCACACTCAGTCATCGCCGTCCGCGCCGGGTCC ACACTCGGTCATCGCCATCCGCGCGGGGATGTGTCTGAAAAGTGTGGTGAGAGCTGTGTT CCCTGCGCATTTCTGAAGGCTCCTAGCCGCTGCAGTTGCCGGGAGCCATGGAGCCACGTG ACCTTGAGGTCCACCGGGGAGAGGAGGGTGCATTTCGGAGGCTAGAAGTGGCACCTGGAG GGGCTGGCCCTGGGTGTGATCATTGAGAGGAGGGAGGTGGAAAAAGATCTGGAAGATGCC CTTGGGAAGCAGAAGAAGGTGGGTGACCAGAGTGGGGTGCCCAGAGGGTAGGGCAGGGCA GACCAGAGGAGGGGGTGGGCTTGGCACCCCCGGGAAGGAGGGATGGGGCTCTGTGAAAGT GAGAGCTGTGTGGACGTGGAGCTTGTGAGTCTGACCAGGAAAGACAGAGGGTTCCAGACG GTGCGGGGGCCCCTTCAGTCTGGTTGTGTGGGGCAGGGTCCTCACCCCCAGGTGAGGGGG CCTTGTAGGGCAGATTCCTGGAAGACCCTCAAGACGCAGGAGCGGAGGCTGCTGGCTGGA TGGGGATGGAGCCGAGAGCTGAGCGGGCAGCCCAGGCCTGAAGGACAGCACAGGGGCCTC TGTGAGGCCAGGAGGGGCTGGAGTGCAACACCCCCTGTGACCCAGGTCTGGTGTGTGACG CGTCAGGCCCCACGGCACCGCAGGCTGGCTGGCTCCCCAGAAGGCCTGTGGTCTCCATGG CCGCAGCGCATTCCGGGGACAGGGCAGAGTGGAGTCAGCAGAGGGAGGAGGCGTGTGGGG CGTCCAGGGATCAAGGGGTCTCTGGGCCTTGCTCCCTTCCCCAGCAGCTGTGAGGATGGT GGGGGCTGCTGTCTGCCCAGGACTGCAAGCGTCAGGCACAGCAGCTGCTGTTAACAGTCA AGGAATGTTCGGGTCAGTTTGAGAACTTCAGGGCCCAATGGCAGAGCCCCGGCAGAAAGA CTCAGGGCAGATGGTGGTTGTCAGCCGGGAGGGGGCACGGAGCCCTGGGGGTGGTCAGGC CCACGTGGCCTTGGGACGAGAGCGAAGAGGTGGGATCGGCTGCGGGAGACAGGGAAGTGG GTGACAAGGAGGCTCAGGGGCTACAGCAAAGGCCCCGGAGGCTTTTCCACACCCGAGTCC GTCCTCGGCCATGCCAGCCAGGTCAGGGGCTCAGTCCTGTGGGCCACCACAGCCGGCCGC ACAGGCAGGGAAGGTGAAGCTCCACGGAGCACCCTGGTGGACAGCGGTGCTGTGGGGGCC ATGGACCAGAAGGCGGAGCCCATGCTGTGGGCTGGGTGGGGTGGCAGCTGCCAGTTCAAA GTCTGTCTTTTGTTTATTTACTTCATAAAATACTCCAGGTGTTTTGTTAGAAATTATTCT TGGCCGGGCACGGTGGCTCACATCTGTAATCCCAGCACTTTGGGAGGCCTAGGTGGGCAG ATCCTGAGGTCAGGAGTCGAGACCAGCCTGGCCAACGTGGTGAAACCCCCGTCTCTACTA AAAATACAAAAAATTAGCTGGGTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCCG GGAGGCGGAGCTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGGCGACAGAG CGAGATTCCGTCTCACACACACACACAAAAAATTAGTTGGGTGTGGTGGTGCACGCCTGT AGTCCCAGCTACATGGGAGGCTGAGACAGAATTGCTTGAATCCAGGAGGCAGAAGTTGCA GTGAGCTGAGATCACACCACTGCACTCCAGCCTGGTGACAGAGCAAGACTTTTTCTCAAA AAAAAAAAAGCAAAGAAAAGAAATTACTGTCTTAGTGTTGATAAATCTGCCTTTATACAT ACCAATAGTTGTGCACACTGAGAGAAGTAGGCAGTTTTGGATCTGAAACTGGCCTGGTGA CACCGCGGGTGCAGCAGGCGGGCAGATGCGGGCACAGGAGGGAGCTTCCCACACTGTTCA GGTCACCAGAGCCTGCGCTTCTGTGGTTGGTTTTGATGAGGACTCGTATTTCAGCTCCTG TCTCTCCTTGTCAGAGGCCGTGTGAGGTGCGTATTGCGGACCGCCGGCCGCGCTGTGAGG GGTGTACATGTGGAGCCGTGACAATCGTGGGAAGTTCTGTTTCCAGCTTTAAGCTTTCGT TTATATTTCTGCATATTAAGAAATGATAAATTAAGACCTAATGAGAAGTTGTGGACTAGA CGTGGGGTGTGTAGGCTGCTGGGAGGAGGGGCAGCGGCCCTGAGGGGTTGTGGGGCCCAT GGGACCATCTGACCCAGTGCATGGCGGAGCCGTGTCCACGTGAGGAGGGAGTAGGAACGG GCTCTGCGCTGTGGCTCCGTGGGCTGCCGAGGGCTGCTGTGGGCTCTGCGCTGTGGCTCC GTGGGCTGCCGAAGGCTGCTGTGGGCTCTGCGCTGTGGCTGTGTGGGCTGCCGAGGGCTG CTGTGGGCTCTGCGCTGTGGCTGTGTGGGCTGCCGAGGGCTGCTGTGGGCTCTGCGCTGT GGCTGTGTGGGCTGCCGAGGGCTGCTGTGGGCTCTGTGCTGTGGCTGTGTGGGCTGCAGA GGGCTGCTGTGGGTTCTGCTCTTATTTGCCCAGGGGAAACCCGAGTCGCTGCCCCTCCTG TCCAGCCTCAGCGCTCGTCCCCGGGTCCCCCAGCAGGTGACCACAGATGATGACGGAGCC TCCTGGAACCGCCTCAGTTTCCCCAGCTGGCCCCTCACTGGCCTCCCCATTTCAGGAGCC CCAGGGCCACTCTCCGCCAGGCTCTCTGTGTCTCCGATTAACCCTCAGGTCGTCCCAGCC TCTTCCGAGCCATGGTTAGGATCGGCCCCGTCCACCGTGTGTCCATGGAAGTGAAACAGG CCACCAGCAGTGGGCAGCCGCGGGCGGGATGGGCTGTGGGGCAGAGGCTGGCGGGCAGGA ATGGTCTCGTGGGTGCGCACCTGGCCTGTGTGGCGCTGCGGCCGTGGCTTCTGCATGCCA GGGTCAGCAGCCATCTTGTCGGGTTTTTAATGTGCATTTCCCAGTTCACTGATACAGTTG AGCATTTAAAACATGCTTGTTTGAAATTTCTCTTTTGTGAAGCTCTCTGTTGGCTAGAGT GGGGCTGGCAAACCCTGTGAGGGAGCAGATGGTGAATATCGTGCGGCCCCAGGCCTCCCT CCAACGAGCAGCGCTGTGTGCTGGGAGCAGGCCCTGCGGGGGCCAGCAAACCCGCTCACA CAGCCCACGGGGCACAGCCGGGCCACGATGGCCAGGCCCTGGTCTAGGTTGTGGCCCTGG AGGCACTGCCGAAATTTCCCTCAGGCCTTGGCTTTTTTTCTCCATGGTGCTTTTGAATAA CTCAGGGTGCTTATCTTTGACTTTGTCATTTCCTTCATGGTCAGTTTTGTTTTCTGTCTC GTAAATCTTCTCCTCATCCACGATCATGACGATACCCTCCTTAGCAACCTCCAAAGGTTC ACGGTCGCCTTTTCCATTGTCCTCACCCACCCGGCCCTGGTTATTTTTGGGGTGGGATGG TGCAATACAAGCTGACAGTTTGGCTTTTTTTTTTCTAATTTCACCACAGGAATGATGTTT ATGGTGTATGTTTTTAATTCTAAGATACACACTAAAATTCACCAGTTTTATTGTGCAGTT TGGGGACTTTTCACCCCCTGTCCAGTTTCATGGACTTGCCGGCAGTGCTGGCCCAGAGCT CGGTCCCCGCAGGCCTCCCTCAGGTCCCTCTGTGGCCAGTCCCTGCCTTGCCTGGACTGT GTGTGCCTGTGTCCTCCCACCAGACTTGCCGTTGTTCTGGAATTGAGTGGCGTGTGGGAA CGTGTGTGCGCTCCTGCGTCTGCCCCTCTCCCCTGTGGGATCGTGGGCACCTGCGTTGCT CACTCTCACTGCCGAGCCGCATCTGCGTGGGGAGGGGTTACGCTGTGTTTATCATCCGCC TTCTGATGGACTAACTAGGTGGTTGTTTCCAGTTTGGGGCTGTTAGGAAAAGGGCTGCTT TGAACATTGTTGTATAAGACTTTGAGAGGATGTGTGTGTTAGCGAGCGTCTTTTTTTTTT TTTTTTTTTTTTTTTGAGATGGAGTTTCAGTCTTATTCCCCAGGCTGGAGTGCAAGGCGC GATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCAGGCGATTCTCCTGCCTCAGCCTC TCGAACAGCTGGGAGTACAGGCACCTGCCATTACACCTGGCTAATTTTTTGTATTTTTAG TAGAGACAGAGCTTCACCATGTTAGCCAGGATGGTCTCCATCTCCTGACCTCATGATCTG CCAGCCTCGGCCTCTCAAAGTGCTGGGATTACAAGCATGAGCCACTATGCTTGGCTGAGT TTTGTTTTTTTTAAATCATGAATGGACAATTATTTTGTCAAATGATTTTTATGCACCTGC TGGGAAGATCATGTGATTTTTCTCCTTGTATCTTTTGTCATAAATTGTATCTTTTTCCCA TAGGCATTAAGCCCACGTTGTTTTCTAGGACTCTGAGTTTGTCAAGAATGATTATCTTTT TGTATATTGCTTAAAAAGGATGACTAACCGTTTTCTTTGGATTTTCACCTCTGTGTTTCC TGGTGAGGTTAACGTTGAGTTCTTTCCGTCTGCCATGGTCAGTGCCTGGTTTTGTCAGGC TCATAGTGTGAGTTGGAAAAAGGCTCCTTTTAGTTCTCTGAGAAGAGTATGAGACTGAAT TATTTGTGCCCTGAGCGTCTGGTGAAACCACCTGCATCCCTCCGGGGCCTGATGCTGTCT TGGAAGGGACTTTCTGACCATTGACCTGGCTCCCTGTAGGTTCTGGAACTTCCTGGGTTT TCTCTGCTAGTCTCAATGCTGGTGAATTACTGTTCTAGGAACTTAGCAGTTTCACGTAAA CTTTCCATTTTATTAGGGTCAAGTTCATCATATCTTGTCCGTGCTCGGACGTCACCTGCT TTAGGTGCACCCGGTTTAATAGTGCACGGCCAGCTCCCCCGAATCCATGGGTCCAGTCAA CACAGATTGAAAATGTTTGGGAACCAAAACAATAACAAATAACAGTACAACAATAACAAT AATGCACATCTTAAAAATACAGTAGAACAACCATTGACATAGTGTTTACAGCATGTTAAG TGTCGTAAGTAATCTGGGGATGGCGTAGAGTGCGTGGGGGGTGGCGTGCACAGCGTGTTA AGTGTCGTAAGTAATCTGGGGATGGCGTAGAGTGCGTGGGGGGTGGCGTGCACAGCGTGT TAAGTGTCGTAAGTAATCTGGGGATGGCGTAGAGCGCGTTGGGGGGCAGCGTGCATAGCT TCTGTGCAGACTCGACACCACTTCATGTCCGGGACTTGAGCACCTGTGGATTTTGGTATC AGCGGCGTCCTGGAACTAGTCCCCCACGGATACCAAGGGATGGCTGTGTGTCACCTTCTA ACATAGTAAATAATTGACCTGTTTGTTAGTTATTGTCTGTCTTCCTTCATTAGAATGCTG GCTCCAAGGTCTGTGTCTGTGTTTTCACTGAAGTCTGAGAACTCCTGTCAGGAGCCGCCA GCTGTACCAGCCAACACAGGAGCCACTGGCCACAGTTTAACTAAAATTAAATACAATTAA AAATTCGTTCGGTTGGCCGGGTGTGGTGGCTCACGCCTGTATTCCCAGCACTCTGGGAGG CCGAGGTGGGTGAATCACTGGAGGCCAGGAGTTCGAGACCAGCCTGGGCAACATGGTGAA ACCCCATCTCTACTAAAAATATAAAAGTTAACTGGGCGTGGTGGCGGACGTCTATAATCC CAGCTACTCGTGAGGCTGAGGCACAAGAATTGCTTGAATCTGGAAAGTGGAGGTTACAGT GAGCCGAGATTGCACCACTGCACTCCGGCCTGGGTGACAGAGCGAGACTCCATCTCAAAA AAAAAAAAAAAAAAAAAAAAAAAAAACTGGGCTGGGCACGGTGGCTCACACCTGTAATCT CAGCACTTTGGGAGGCTGAGGCGGGAGGATCACTTGACCCCAGTAGTTCACGGCCAGCCT GGATAACAGACTGAGACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGT GCATGCTTGTAATCCAAGCTACTCAGGAGGCTGAAGTGGGAGGATTGCTCAAGCCCAGGA GGTCAAGGCTGTAGTGAGCCAAGATCGTGCCACTGCACTGCAGCCTGGGTGGCAGAGCAA GATCCTGTCTCAAAAAAAAAAAAAGAAATAATAATAATTATAATGAGATCCTTCAGTCCC ACAAGCCACAGTTCAGGTGCTCCACGCCATGTGTGGTCAGCAGCTGTGCTGTTGGGTAGT GGAGATGTGGAAGCCCCCAGTGTTGCAGAATATTCCGGAAGCCTGGCTTTGAGCCTGGCT TCATTCTCTTCATCTTGTTTCTCTTCTCCCTAACTCAAGTGCCTCAGACATGCCTGCTGA TCTCCCCTTATATTTGCCTGGGAAGACTAACTCTACTCTTTCCCTTCTTCCTCCCTTTTT ATGTAAAAGTTAACTGAGCTTCAAAGATTAGTTAATAAAAAGTGCAGTTATGGGAAACCG GAAGAGTAGAAATGATACAAACGGGGTAGAAAATGAAGAGCATGAAAGTATTTAATCTCT GTCACTAAGCCACAGACACTGTACGTCATCCCAGGCCCCCACTTTCCCCAGTCTGACTCC AGCCACCTGTTTCCCCAACTCACACAGGAACGTGTGGGAGGCCACCGAGGTTCCCGGGGA AGCACTCCCAGCATGGCAGCCACCCTGATGCCCCATCCCAGACGCAGGGTCCCTACGTGG TCCCCTGGTCCCGGGTGGGGACTGTGTCCCTCCCCTGCCCCTCCCTCCCTGTCTGAGGCC CCAGGTGCCCTCCCTGTCCTCATCCCCACTGAGCCCAACACCAGGCTCAGTGCCCACGCC GGGGCCCTTGGTGCACGTCTGGTAGGCGCAGGCAGGTCTGTGACTGGGAGAGAACATGGT GCCCTGTGCACAGCAGCAGAATTGCGGGCATCTCTTGGCTGCGTCGTGGAGCCAGCCGTC ACTGCCTTGCCTCTGAGGTCTTGCATTTGCCCAGATCACCCCTGAAATTCACCCCTCCTC TGGGGGGCTCCACAGACTCACATCCTGCCTTCTTGGGCCCAAAACAGCATGATGGGGCCC CCAGCTGCCCCCCCACCCCCGTGGGCCACGTGCCCACTCCTGCTGTCTCCGATGCCTTGG GCCTGGGCTCAGAGACGCCCGACAGGCACCGAGACCAGCCCGTGTCTCCCGGGTAGAGCC TGTTCTTCACGGTCCCTGTGAAGAACTTTTGGTTATTTTAAGCAAGGAACAGAGCAGTGT AACCGAGCCAGGCTTGGCACCGCGGGTGGGGTGGGGGTCGTCCGCCTCCGGCCCACGGGT AACCCTGTTGTGCTTTTTCTCCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTG CTCAGGTAAGTGCGCGTAGGCCGACTGCCCTCTTCTTTCCGCACCTGTGAACTGCCGGAC TCCGCCGGGACCACGCTTTGTGCATGTGGTCGGCGTTCCTTGCAGTGCCTCTGAAACGCA GGCTCTGAGGACAGGCTGGAGCCATGCGTGGGTCCTTAGCTTTTCTCCCGGTCAGTACTT CTGATTGACCCCATTCCGCCCTTTGCTCGGTAGGGCTTGGTTGCAAGTTCCAGTAGGAAT GGCGGAGTTGTGGCAGTCACACATCCATGACGCGAAGTGAACTAACAGGTGCCGTTTCTG TGCTAGAAAATGGAAAAAGAGCCAGGGCCGGAAGGAGGGTGCAGAAGCGAGTCCGCGTGC GGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGAG GGACGGACACGCGGACGTCTAGCGGAGGTGAGGCCCACGCCCCCCGACCCCGGGGGTCCT GCTGACTCCTTGCCCTGCCCTGTTGCTGGTTGTGGCGAGGGCCGGCGATCATTAGGAGCC AGCTGGTCAGGACACGATGCAGTGTTCACGGTTCACTGCCGAGTTTTCCTGGCCCCTCCT GTGAGAGTCCAAGGTCCAGCCAGCTGTGGGGGTCCCAGGCCTCGATGGCAGTGCGGGGTG CAGAGGGCTGGTCTCCTTCCGTCACTGGTTCACTTGGGTTCCCGGCGTGTCGCTGAGGAG CAGTGCTGCTTGGGGGCCGAGCCTGGGGCCTCAGCCCAGTGAGTTGTGAGGCGGTCGGCT AGCATCCTGCAGGGAGGTCCTCAGGGGCGCAGGGCAGGGCTATCTCTCCCCTCCCGGGTG CTCTGTCCCCTCGTGGGTGGGCGTGGCCCTCAGGGGTGTAGGGCGGGGCTCCCCCTCCCG TCGTGGGTGGGCGTGGTCCTCGGGCATAGGGCGGGGCTCCCCTCCCCTCGTGGGTGGGCG TGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCCGCCCCTCGTGGGTGGGCGTGGTCCTCAG GGGCGTAGGGCGGGGCTCCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGG CGGGGCTCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCC TCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCCCTCGTGG GTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCCTCCCCTCGTGGGTGGGCGTGG TCCTCAGGGGCGTAGGGCGGGGCTCCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGG CGTAGGGCGGGGCTCCCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGG GCTCTCCTCCCCTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCC CTCGTGGGTGGGCGTGGTCCTCAGGGGCGTAGGGCGGGGCTCCCCTCCCCTCGTGAGTGG GCGTGGTCCTCAGGTTGGTAAGGCGGGGCTCCCCTCCCCTCGTGGGTGGGCGTGGTCCTT AGGGGCGTAGGGTGGGGCTCCCCCTCCCCTCCCGAGTGGGCGTGGTCGTCAGGGCGCGGG GTGGGGCTCCCCCTCACCTCCCTTCCCTCCCTACCCTCCCCTCCCCTTCCCTCCTCCCCT CCCTTCCCTTCCCCTCCCCTCCCTTCTCCTTCCCCTCCCTCTCCCTTCCTGGGCAGGCTC CCGTGTCCTCAGTATGCATCAGGTCTCCCGAACCTCACAGCCCCGCAGGGAGGAGGAGAA GGGGAGGATTTGACTTTGGAAGTCTCTGTGACCAGGTGAGGACCGCAAGCGTAAAGGTGG TGGCAGAGTGGTCGGGGACAGGCCTCACCCACAAACATGTGGCCCCTGGATGAGCCCAGC TCTCAGCTGCTTCGTGGGACTGCAGCTGGACGCCCAGGCCCGCGCCTGCAGCAGGCGATG TGGGGCTCAGCAGAGAGCTCCAGGCTGGGCCTCTTGGTGGCGGTGATGACGGAAGTGGTG TCACGCATGCAGCAGTTTGGGTCGCGGCTTTCCGTCCCCACTGAGGGAAACTCGTGCCTG CTGCTCCCCTGGTGAAAGGTGTGGGGAGCGAAGTCCCAGTAGTGGGGTGCACCTGGCCAC CCTGAGTCCCCACCAGCCTCCGCACGCGGAGCGGCCCTGCTCTCTTGCCTCAAGCACAGA AGCAAATCACCAGGCTCTGCCTGCCGTCGTGCGGTGACATCGGGGGTCACCTCCCCGAAG GCGCAGGTCTGGTGGGCGAGCAGAGCGGCTGCGGCAGCTGTCAAGGCAGGGCCTCTGCCA GCCACTGTGGCCTGGCATTGTGCCCACCCTGTGAGGGTAGGGTGGGGCCCCTGCCGCGTG CTGCCTCCGCCCCTGCCCCGTGCTGCCTCCGCCCCTGCCCCGTGCTGCCTCAGGCTCTGG GAGACACAGCCTCAGGAGACACCGTGGAAGCCGCGCCGGCCCCACAAGTGAATGGGGAGG AAGGGGTGTGAGCATACAGCCCAGACTCTAAACTGGGCCCAAGGGTCGCGCTGTGAGCCG CAGAGGGTCCAGGTGCCCAGAGCCTGCCCATCCTCATCCCACCCGGCAGCTCTGCCTTCG CGGGCTCCTCCTGCTCCTTCCGCTTTCACAGAAGACAGACAGCTCGGGGATCCTGCCTCT CTGCAGCTTTATGGACCCTCCTCAGTCCTCACTGCAGGAGGAGAGGAGGGGGTGTTGGGC ACAGAGAGAAGCCAGTGCGGGGGAGCCGGGGGCTTTTGAAAAGGTGGGCTTGTCCCAGTG CACGCAGACACTGGATTGCTGACCGTGCCCTGCACATGGGAGCCTGGGACCCCGTGAGCC CAAGAGGCTCCTGCCACCCAGGCCTCAGGGCCTGCACTGTCCTCCCTGGGGGCGGCTGTC AGAGCTCAGCCAAGGATGAAAGGCATGGAAGAGTTTCAGGTGTTAATTAATCGCGTTTTC TCTTGTAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACA TCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGC ACACCTGTACGTGCCCTGCCCGCGCCACCCAGGGAGGGCGCGCCCTTCCCAGCTCTGTGC TCTTCAGAACCTTGGCTTTTGTGTTACCACACGCTTTTAGCTCAAGCCCGACAAAAGCAG GAACCAGGACCAGGGGCAGAGACGATCTTGAAGATAAGTCAGAAAAGTCATTTCACGCTA AAGGTCCTGTGGGTGGTGTCAGAGCAGATGAGGCCTCGCTTAGGAGAGCGAAACACAGGA GAGACCCCACATTCCTCCCACGGAGCAGCAAGGCCAGTAGCCGCTGTGACAGTGCTCACT GCTGGCAGTTTCCAAATCTCCAGAGGAGTTCCTTAGATCCTTCAAAGGGGAACCTTCCAG TGTGTTCTTCACACCTGATGTGCGTCCTCACACCTGATGAGTCTGTGCTTTGGTGTTAGA GGACTCACACCTGGGGCTGGACCTGAGTGTTTTTCTAAGTGTGGCTACCGCTGACGGGCA GGTGCCATCCATCAGGCTGAGGCTCGGCTCTTATGCTAACCTGAGGCCCCATGGCTGGCG GCCCTGCTGGTGTGGACGACCGCTGTGTGCGTCTCTTGATGGCTGGGGAGCATTTTGTTT AAACAGGATCTTTAAAATGAAGTGTACGCTTATAATACAAGTGATGCTTGTGTATTTCTC ACTTTAGGAAATAAAATATTTGCCAATTTGATAGAATTTTGACTTTAACGTTAATC bcftools-1.21/test/csq/ENST00000400151/ENST00000400151.fa.fai000066400000000000000000000000211467060157400214760ustar00rootroot000000000000004 28736 19 60 61 bcftools-1.21/test/csq/ENST00000400151/ENST00000400151.gff000066400000000000000000000024411467060157400211240ustar00rootroot000000000000004 ensembl_havana gene -15 64876 . + . ID=gene:ENSG00000185619;Name=PCGF3;biotype=protein_coding;description=polycomb group ring finger 3 [Source:HGNC Symbol%3BAcc:10066];gene_id=ENSG00000185619;logic_name=ensembl_havana_gene;version=13 4 ensembl_havana transcript 21 28716 . + . ID=transcript:ENST00000400151;Parent=gene:ENSG00000185619;Name=PCGF3-009;biotype=protein_coding;havana_transcript=OTTHUMT00000318560;havana_version=1;tag=basic;transcript_id=ENST00000400151;version=2 4 havana exon 21 207 . + . Parent=transcript:ENST00000400151;Name=ENSE00001435879;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001435879;rank=1;version=3 4 havana exon 24867 24905 . + . Parent=transcript:ENST00000400151;Name=ENSE00001354124;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354124;rank=2;version=2 4 havana exon 25207 25347 . + . Parent=transcript:ENST00000400151;Name=ENSE00001354120;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001354120;rank=3;version=2 4 havana exon 27909 28716 . + . Parent=transcript:ENST00000400151;Name=ENSE00001556838;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001556838;rank=4;version=1 4 havana CDS 27918 28439 . + 0 ID=CDS:ENSP00000383015;Parent=transcript:ENST00000400151;protein_id=ENSP00000383015 bcftools-1.21/test/csq/ENST00000400151/ascii-art.txt000066400000000000000000000006041467060157400212500ustar00rootroot00000000000000 28388 TTCACACCTGATGTGCGTCC T CDS 27918 28439 . + 28388 28400 28410 28420 28430 28440 eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee........ GGGAACCTTCCAGTGTGTTCTTCACACCTGATGTGCGTCCTCACACCTGATGAGTCTGTGCTTTGGTGTTAGAGGACTCA GGGAACCTTCCAGTGTGTTCT-------------------TCACACCTGATGAGTCTGTGCTTTGGTGTTAGAGGACTCA bcftools-1.21/test/csq/ENST00000400151/long-del.txt000066400000000000000000000004411467060157400210740ustar00rootroot0000000000000028388 TTCACACCTGATGTGCGTCC T frameshift|PCGF3|ENST00000400151|protein_coding|+|157SSHLMCVLTPDESVLWC*>157SSHLMSLCFGV|28388TTCACACCTGATGTGCGTCC>T 28388 TTCACACCTGATGTGCGTCC T frameshift|PCGF3|ENST00000400151|protein_coding|+|157SSHLMCVLTPDESVLWC*>157SSHLMSLCFGV|28388TTCACACCTGATGTGCGTCC>T bcftools-1.21/test/csq/ENST00000400151/long-del.vcf000066400000000000000000000010011467060157400210240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 4 28388 . TTCACACCTGATGTGCGTCC T . . type=ENST00000400151:727940-TTCACACCTGATGTGCGTCC-T;EXP=frameshift|PCGF3|ENST00000400151|protein_coding|+|157SSHLMCVLTPDESVLWC*>157SSHLMSLCFGV|28388TTCACACCTGATGTGCGTCC>T bcftools-1.21/test/csq/ENST00000409523/000077500000000000000000000000001467060157400166475ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000409523/ENST00000409523.fa000066400000000000000000002003231467060157400207770ustar00rootroot00000000000000>2 2:120059781-120124424 TAAGAATCAATATTCCACAATAATTTTTAATAACAATTTATTTCCCTTTAAAAAGATCAA ATGTTTTTCTCATAATATATTATTTTACAACAACAAAGAAAAAGAAAGAGAGAAGGAAAG ACCTGAAGAGAAAGAAATAACCAGATTTTAGCTCAAAGAGTATAGCCTGGGATTAATTTT TTAAGATTTGTTTGTCAATTTCAAAAATTCAGCAGTGGAATAAAGAGCTTAATACAGGTA TGCAAAAAGGAAGCCCTCGAGATGTTTTCACCAGGATGAAATGGGATTAGCTTTGTAGTT CTTATAATCTTCTTCACAGAAGAATGCAATTTCAGTTTCACTGGCTGAAAAAAAACAGAA AATGGAAAAAAAGATTTTAATGTAAATCTAAATTTTAAACAAGTATGGAAATCCATATGA CTTTGATTCGGTATTTCAGAATAGCTTCAGATGCCCAAAGTGAAAAAGATGAGTTATTTG TTGGGTCGCACAATGCATTTTACCAAATCAACAAGAAGTTTCAGGTGAAGTTTTAAGAAT CAAAACCTCAAATGATTTAAAAGTAAAAAAGAACAAAAAATAAAAAACCAAAAATTAAAA TCAAGAGTTAATACAAGAATCTGGTTTTCAGGAAATCATAAAATTGCTCATTTACAGTCT TTTTTACAGTGCTAGGAAATAAAAAACCTTGATTTTTTTCTCAAATATGCTACTCAGGTA CTGAAGGAAGGGGAGGGAAAACTCTTTTCCCCCCCTGAAATTAGCCTGTAGGTATAATAA TTTAATACTTAGAGGATCAGTAGAATATTTTACAGATCACTTTACATTCTCCCTCATGAC CCATCAAAATATGTGTCTGAAGAAGTTAATTTTTTGCCCTGCTTATGATTAATTCATGCG GCTTCAACAATATGCAAAGTGAAAGACACAAATTGGCTTCTACCTCAATACCTTCAAATA CCTCTAATTATTCACAAGGGAGATGGCACAGCTAAAGGACCCATGAAGGTTCAGAGCAGT CACAATTCTTTCAACCTAGCAGGTCAAGGACTGCGTCTTCTATAACAATAAGTCAGCAAC ATTATTAATTCAGGCTAGAGACAAATCTGATGGAAAGCCTTCCAGTTATTAAACATGCAA TTCTTTAAGGTGTTGTGCCAACAAGTTCCACATTCATTTTTCAAATTAAACCAGAAGTTA ATACAGTCTGCTTGGCTTTTACAGAAAGAGCAAAAGGGCCTTCAGAATCTCCACAAGAAA ACAGACAAGATTATTCGTAATGCATACTGAGCACTCAATTAACATACTCTCTAAAAACAG ACAAGTAAAACTCTCCAAGTCAAATAAATAGCATAATAAGAAAGGGTGCCAAGGATTACC ACTCGTCTCTTAGTTTACAACTCTCATCTCATCATTAGACTTTATCACAAAATAATGAAA TTAATGAGATTAGCATGCCATTTCATTAAAAATGTTTTTGCTGTTTTCAAGAATATCCAA TTTAATGTTTGTTAATCATAAGCTACCCATGCTCATTACAGAAAATAAACAAGTGTCAAA AGAAGAAAATAAAGCCACCCATAGTCACAGATCCTCATTCCAGTCCTCTACTATATCTTC AAGATTAAATTTAATCTGAGTAGATGAAAATCAGACTGCAACCTCGCATGACAAGGAGCC TGTGGGGGATACAGCACAGAGAAACTGGAGATCAATAAGGAGGAGCTGTAAAAAGATGCA CCCTGTGCAAACAGTAAGTTAAGGTACAGTTAAATTTTACAAGAAAGTGGCATCTAAAAG AATGGGTAAAAGACTCCTCCACACTTGGAATCAGTGGGAAAAAGAAAATCAAGAAAGAGA GCTTCAAAAACTTCAATATTCAAAGATATTTGGAAATCTATCCCTTATAGAAAAAGCTCC TGGGGTTTCCTTTTTTGAAGCAAAGCATGCCCAGAGGTAGATGTATATAATTTGCAAGTG ATTCTAATCAACCTTCTAATGAAGAATGAGCAAAAGACACCCTGTTCTTAATAATCACAG AGCAAGGTTTTATCTGTGATGTGCTATTTACATACAGAACTTTACACAGTGCTTTGCCCA CACAGCACTTCGCTCAGTCCACGCTAACTGTAATTACAATTTTCACTTACTGCAGTTGAC ATTTATCTGAACCCCTTTTGAGAAACTAATATGTTGTGTGGCTCTTCAGCAATAGTAGGT TCAGAGAAGCTGCTGGAAAGCAAGGAGTTCTGTTTTGACACATAGGTTCTTTTGGATCCA GTTAACTGAAACATCAATCCATTATTTACATAAGGCATTTATGCTAGCTCTCAAAATGAG AGTCTGCAGTGTAAAGATTTTATTTTCAGATGACTGCACTTGTTTTCAGGAAATCTAGGT AAACAAATGGGTTAAACTATAATACTTCAGGCTGATTTAAAAAATTTTTCACCCTTAACA AATTGGAAAACACACAAATTAAAATTTACTCCAAACATTCAAAAGTAAAACATTAAATGG GTTTTAAATTTTAGTAATGTGGTCCTTAAGAAGAAGTAGAATATAATGTTTTCTTACATC TGTAAGACTCTGTGGAAAATGTTTCAGAGAATGATTTCAGGGACTTATGCTGCAAATTTA TTTGCCAATTTATGTGAAAACCAATTATAAATGATTTTTAAGGTTTCTACATCATCACTT TCCACCATTATCCCTTAAATTCCTGCTTCCCAAATACTATTTAAAATGGCTCCTTTAAAA CTGGCTGGGGATGAACCCTCAGGAAGTCTACCTTGTGCTGGTCCCCCAGGGCACCTGATT TTAAATTAAATGTGCTGCAGGCGGCAGTGCAGTCAGGTGCAGAGTGCCTTGGCATGGGAA TCTGAAATGAATGTGCAATCTAAAATCCAATAAATACACTGCCACTTCATCCCTTCGTCT TACTATCAAATGAAACCAAGAACCCTCCAAATACATTTGCAGGATCCTTTTAATACTGAT GTTCAAGTTTAATGAAATAAACACAAGCTAGGGCTTTCAAACTTTGGATATAAAATTAAT CATTTTATAATGCTTCCAGACAGACAGACAAGACACACACACACACACAACTTTAACAGG AACATAATGATAATGACTTTAAATGAAAGAATATAAGAACAATCGATTTTAAGTATAAAA TCCCAAGAAAAATTAAATGCAATGTATTTAAACTCTTAAACTAATTTATCTCAATAAACT CATCTATCAACAAGGATTTACCCATATGTCTGAGTCCCTAGCCTCATGCTAGTCAGCACC AACGTAGTATGAGGCACAGCCCCTGTTGTCTGGAAAAAGGAGCCTGAGACACACGCACTG ATTTTGTGGTACAGAAAATCCACAATCTTGGAAGCTGACATGTGACAATAACTGCACACT GTTGACAAAAAAAAATACAGGAAGGGCGAGGTGTGGCTTCTGTGGCAATCTGAGACCAAA AGGACAAAGTTTCACCCTCTCTCCCGCTCTAGGAGTATAGCCTAGCCTCCCAAATGTCAT AAAATCCTAATCTATAAATCATTCAAAGCTGTGCTCACAGCTGAGTTATATTTCTAAGTT TTCATCACCAACAGACGTCCCAAGTGCTGTGCCTTTTATTTCATGACTTGCTTCAAATAT TTGTTTTGGATCTGCTGGCAGAGAAGATTTCAAACTACAGTTTGAAGAAAACAACTAGCC AAAAAAAAAAACAACAACAAAAAAAAAAAAAAACAAAAAAAACCTCGGTCTTTGATAGAC TGGGTACATGCCTGTAATTTCCACCATGGTGTGGGAAGGTAAAACGGGAAACACTCTACA GAGGTTCACTCTGAGTCCTGCTTCTGGAATCCCCCAGTTTCCTGGGTCCGACACCCACAT TACCGAGTAACCAGATTATCACTGTTTCTATGTAAGAGTGAAGAACGGCCACCATAACAT ACTGTCGAAGGAAGAAAACACGCATGACCTAAAATATTGCTACCCAGAAAAAGAAAGGGA ATGGGACTCACACCTTAAGGAAACACAAATCAAACATCATCCCGAAAGAGAAGGGGGAGC CACAGAATCCCACAATATTAGCTGTACAGACAAGATCACCCAAAGGGGCGAGGCGTGAAC GACAGGGTTCCAGTTGGGGGCAGATGACAGAAGTGACACGCAAAATGAAAACGAACCACG AGGGAGTTCTGGAATTATTACAGGACCTGGCTTGCCGAGAATGCTTCCCTCAGATAAACA CTTAGAGTTTGGCCGCTGTATCTTGTTTTAAAATGTTTCCAATGAAACACAACTGGCTTT GGAAGAGTTACCCAGCCACAATTTCTCTCTTAAACCAGACCAGATTCGAAAGACAACAGT AGTAGAATGTAGCAAAATGAAAGAGAGAAAATAACACTTAAAAAAAAAAGCTTACATGTA AATTTATTACTTAGGGGAATTAGCCCATAAAACTACAATTGCTGACAAAAAATTATAAGT AACATTTCTAGGTAAAAGTCTCTTCTTGCTTCTACTGATCAAATCTTTTTGAAGTACGTA TTTTCGTACTGGGTCCACAAGCAAAAACTCCACTGACGTCAGGTGTAGAATGTTCCACGG GGATCTGCAGTGCAGATAAAAAGCCAAAGGATGAACTAGAGAATTTCTCCCTGAGAAAAG AAATCTTCAAACACCTTTTTTTCCCCTAATTTCCCCACTTGCAGCCTTTCTTTTCCTTTC ATGACTACTGCAGAAAAGTCCTAACGATAAATTTGTTACCCTGGCATTATTCCCATGGCA ACTGGCTGTGATAGCAGTGACAGCTCTACAGCAAGATCAAGCAGTGAAAAGGGAGACAGA GATGACTTCGAATTTTTCTCTTAAACCTCTTAAAAATCTAACCAGACACGGCACTGAGGG AGGGAAAATTCCCTAGAAAAATCACATATTTCAGGCCAGGCACAATGACTCACGCCTATA ATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACTTGAAGTCAGGAGTTCAAGACCA GCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGG TGGCACATGCCTGTAATCCCAGCTACTCAGAGGCTGAGGCAGGAGAATCACTTGAACCTG GGAGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCTAGCCTGGGCGACAGAG AGAGACTCTGTCTTAAAAAAAAAAAAAAAAATCACATTTCAAGTATCATTTTCACAACTC AATTCTCACTAGAATTTTTTGTTGCTCTCCAGGTACCCTCATCTCCTTCCCCAGGTATAA CCTCAGCTTGTCCCCAAGAGCATAGCAACACCACTCTAGATAACAAAGAGAAAATCGCTC CCTGCAGGGACCCAAATCACCCCGAGCCCAGGGTTGCTGGCTTGCCGGAGTTCGGAGTTA GGAGTTCGGAGGGCAGTTTGGAGTCCTCACAACACCCTGAAATGAGTGGAGAATCTGGGA AAATAATCTGACTCTGATCCAGGACCAATAGCCTTAAAGTAAGAGGACAAAAAGAGGGAT TTGCTTCTCACCTTTACAGATGGTTCATTACATAAGTCAGTTTGAAATTAATCACAACAA GACCAACAACTCAATATTTTAGTAAAGTCAAAACTTGCCAACTGCCTTCTCCAGGACAGT TTCCAAACAAAGCAGTTGTTCCTGAGGGCCTTTTACACACATCACTCCGGATGCCTTCAT TGTTTTACACAACCTTTATGACAACCTTCTAGAATAGGTTTCATTATTCTGTTTTTACAG AAAACAAAATAGAGTTTCAGAGAGGATAAGAGGCTTACAGAAAGCAAGCAAAGCACACAG CCTTCATTCTAACCGATTTTCCCCAACTTCATGGGTTTATACTTTTAAAAAAAATTCGTC CTTTAATTACAAGGAATACATGTAAACTGTAGAAAAATTTTTAAATCACCATAAAAGCAA TTAGATAATACAGAAAAGAAAGAAGAATATCAATTACTGGCAATGCCAGCACCTCAAGAA ACCATTTCTATAATTTTGGCGTATGATCTTTTCTCCATATACGCATAAACAATAATCTTA CATGTATACTTTAAACATTTTAAAACAATAATGGGGTCGGGCACAGTGGCTCATGCCTGT AATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGAAAACCGAGGTCAGGAGTTCGAGACCA GCCTGGCCAATATGGCAAAACCCGGTCTCTACTAAAAAATACAAAAATTAGCTGGGCATG GTGGTGCACACCCATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGACTTGCTTAAACC CAGGAGGTGGAGGCTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAG AGCAAGACTCTGGTCTCAAAACAAAAACAAAAACAAAAAAACCCAAACAATAATGGTATC ACACAGTATGTTCTATTTCTATTCAATAAATCAAGCTCTACATCAGTGCTTCACATACAG GGAAGGTCAGGGCTAACCCCACCACCCTTCTGAAGACTTAGCACAACCTCACAGCTTGTC CCTGTTGGCTTAGAAACAAGTACCATTGAAATTCAAACTTGAGAAAGTCTTATTGGTCAA ACCGACCCACAGAAAATTCAAGGTCATATTCATTCCCGACGGTGGTATAAGAGTATCCAT TTTCCTACACCTTGAACTCCCTTGGACAATGCCACTTTTTCATGTCTGCTAATCTTATAA CAATTGCTGCTGTCCAAGGTCACCCAGACAGTAAAAGACAGAATCAGGTTTTGGACCCAA GCACTCTGGCTCTGGACTCTGTTATTTTCATAGAGATGAGCATGCTAATTGTTGTGCAGG CTAATCTAGAGCTCCTGGCCTCAGGCGATCCACTAGCCTGGCATCCCAAACTGCTAGGAT TACAAGCATGAGCCACTGCACCTGGCCCCAGACTAGAGTCTTAACACTAGACTCTACTAC ATAAAACAGTATCTATGTACTCATTTCTAATAAGTACTCATTCTCTCCTAATAAGGTGGA GCTATTTTTTATGTGTGAGTTATTTCTTCTATCAATAGAATTTTTCTTTTTCATAGTAAT TACAAGGGCTCTTTATAAAGTCAGGCTAGTAACTTTTCTTTTTTTCTCTTTTTCTTTTTT TTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCTGT GCTGGAGTGCAGTGGTATGATCTCAGCTCACTGCACCCTCTACCTTCCAGGTTCAAGCCG TTCTCGTGCCTTAGCCTCCCAAGTAGCTGGGATTACAGGCGTGTGCCACCACACCTGGCT AATTTTTGTATTTTTAGTGAAGATGGGATTTCACCATATTGGCCAAGCTGGTCTCGAATT CCTGACCTCAAGTGATCCTCCCCGCCTTAGCCTCCCAAAGTGCTGGGATTATAGGCATGA GCCACCATGCCCGACCCCAGGCTAATAACTTTTTATCTGTTGTATATGCTGCAGATATTT TTCAAAGTTTATTGTTTCTCCTTTAACTGTGTTTACAGTTTTTAGTTTATAGGTAGTCAA ATTTATCACTTCTCCCCCTTTATGGCTTCTGTCTTTGAGCTCATGCTTGGAAAACTCTTC TCCTTCCCAAGATTATGAAATTATTGAACTACACTTTCTTTTTAAAAAATTTTTTTACAT TATAACATTTAACCCATCTACAATTTATTTTGTAATAAAAACAGAGATGAGATACGAGTT TGAATTTTATTTTCCTGAATGCTTTGGCAATGGGCTTGACATAATTTTCTGGCTAAATCA TTCTTTCCTCACTTATTTGAAATGTCAACTTTATCATCCTGTGAAATATTACCCTTTTTT TCATTTTTGGATTCTCCAGTGTTTTCCATGGAGCTGTCTGTCAACACCCCCATTAATATC AGTCTGTAATATTCATTATGCTTTATGCTTTAACAACAAGCAGGGCTACCTTATGGGTGC TACATGCCCCAATCACAAAGGTGCCACCTGCTACAATAATATAATAGCATTTAAAGAAAC AAATGCCAAATTTAAAATCATTCTTCAAAATAACAACCTTACATATTCATAACATGGAAA GACAAGAATATTCTAGCAAATATTGTAGACATCAACACAGAAATCAAGTCTAAGATTTCA CAACATGGTATTTAAGATCCTATTTAACTCAGAAGATCTATGTCAGGAATTCATGCTCAT CACGTGAATCAATCAGAAGTAAATTCCTGATACAAGTGATTAAAGTAACTCAAAATAATA CTTGTCAAAAAAAAAATTCAGGCTCCCAATGTGCACCTCACTAACCGTGTTCCTTAACAA GTGCATATAAATAATTATGAACAATGTGAGGCCGAGGCAGGCAGATCGCCTGAGGTTAGA AATTCGAGACCAGTCTGGCCAATATAGTGAAACCCTGTCTCTACTAAAAAAATACAAAAA TTAGCCAAGCGTGCTGGTGCACACCTGTGGTCCCACCTACTCAGGAAGCTGAGGCAGGAG AATCGCTTGAACCCGGGAGATGGAGGTTGCAGTGAGCCGAGACTGCACCACTGCACTACA GCCTGGGCGACAGAGTGAGACTCTGTCTCAAAAAATAAATAAATTAATAAATAATTAAGA AGAAGCATGGCTTGTGACACTGCATCCGTCACCAACCGCAGAGGTGTGTGAGGGGCACAC TGCCTTTAACCACTCAGACCTCCCTGACAATCTCCACTCCCTCTCCTGCCAGATCAGCTT TAGGTGTACATATACGTAGAATAACAGTGACATCTAATGGTCACAAAACATGTCACATAA CATTTATTTAGAATAAAACCACATGCACATTCTAGGCTGGAAGGCCCAATCAGGTACTTT TCAGCTGCACACACCAGGTTCCTATTTTAAATTCCATGCCTTGGTGGGCCCTGAGTGATT CGGAAGACTATCAAAAACCACACTGCATGTGATACCAACAATGCGTTTCATTATTCCTCA TTAGTTCTTACTATGTCCATTTCTCTCCAACCATCGGCTCAAGTGACAATGATAAGAGTA AGTAGACGTGGTACTTACAACCCGTCACTTAAAATGACCCTCAGGAGAATTCTGAGCATA CCTTCTGAAAACAGCCATTTGCATTCTGCATATTTGGAGAGCAGACACCTACTGTCCTCA GCCAAGAGATCGGAATGCACATCATTCTCATCCTCCTCCTCTGAACAGTTACCGGGCAGT GTCAGGGGGACCAAGGACAGCATTTACTTTCCAGTGAGTTATCCAAATACCATCAGCCAG GCCTCAGGATAGGCCGGCAGAGGTCCCCCTCCAGCAACACAAGGCCCCCTTCCTCACCGA TTCCAGCTGCTTTCAGAGTGCTGTCTTCTTTCAGCAGGAGTCTTTCGTCATCTTCCAAAC TCAACACAAGTTCATTTGTCTAAAAAAAAAAAAGAAAATCTGCATTTTATCAGTACTTAC ATGGGTTTGTTTGGTGAGACTTCTCAAAGACACAGAGTTGTAACTCTGAGCACAGCAATA ATCTAAGTAGATTCCACTGCCCTGGCCGTAATGAGGGCAGTGAACAGAGGCACAGTGAGG TCCTGCCGAGCTCACGCACCACATAAAGCAGTGGGGACAGTTCTGTGGCATGGGCGTGAA GTCAGATCAGGATGCAAATCCAGACTCCACCAGCACCCAGCTGTGTGTTCTCAACAAGCT ACACAACCTCTCTAGGACTCGATTTCCTCATTGGTAGAAAAGGGGAGGAGAGGCCCCTTC CTCATCACCTGTGGTAAGGGTGACAGGATGGGGCATATAAACCCTCAGCAGTGCCGGCCG CAGGGTGAGCACTCTCTCTTAGCTGTCACTGTTCTTTTGCTGCATCATCATCATCATCTT CTGCCATCCTCACCTGGTCAGCGACAGAGCTGAGCTTCCAGCTCTGGCCAGTCCGACTTC TGAGAGAAGCAAGTATACTTCCTTTTTTCGTTTTGTTTTTCGAGACAGGGTCTCACTCTG TCACCTAGGCTGGAGTGCAGTGGCGTGATTATGGCTCACTACAACCTCAGTCTCCAAGGC TCAAGCAATCCTCCCATCTCCAGCCTCCTGAGTAGCTGGGACTGCATACATGTGCCGCCA AGCCTGGCTAATTTTTTTTATTTTTAGTAGAGACGGGGTCTCACTATCTTGCCCAGGCTC GTCTCAAACTCCTGAGGTCAAGTGATCCTCTGACCTTGGCCTCCCAAAATACTGGTATTA CAGGCATGAGCCACCACACCTGGCCACAAGTATACTTCAAACGGCCAGAAGTCCACATAT CTAAAAACCTTGCCCAAGCTAAAAAACATCTGGTTCCATGTCACATTAATTGGAATATTT CTCTATGTGATTTGGGGTGGGGGTAAATGAGAGTGCTCTCCAGTGATATTTACAAATCCA GTGAGACTCATAAATACAAGTGAAAATTTAAACTTGCTATTGACTGGGTGCGGTGGCTCA TGCCTGTAATCCCAGCACTTTGGCAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGATCG AGACCATCCTGGCTAACATGGTAAAACCCCGTCTCTATTAAAAATACAAAAAAATTAGCC GGGAGCGGTGGCAGGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGC ATGAACCTGGGAGGCAGAGCTTACAGTGAGCTGATATTGCACTACTGCGCTCCAGCCTGG GCGACAGAGCAAGACTCCATTCAAAAAAAAAAAAAAAAAAGTTGCTATCTGCCCCTAAAT AGCACAAAGAGATAACCACTAGTGGCACACAGCACTACTTGTCAACCAGAACACACCTGT TTAGCAACATATTCTATTTGTAGAATACAGCTGAGACAGAGAGTCAACAGAAAGGCCTCT CAGCAGCCAAATCAGAAGCCCAAGCCACGCAGGGTTTATGGACCTCATTCACTGCAGAGC ACAGGGGCTTAAAACTCCAGAGCATACAGATTAAAAGAAAAAATACTTTACTCAAAAAAT CATTTTAGAATAGGTAATACAGTCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAAGAGG ACTGTTTGAGCCCAGGAGTTTGAGACCAGCCTGAGCAAGATAGCAAGACCCGATCTCTAC AAAAAAAAAAAGTTTTATTTAATTAGCTGGGTGTGGTGGCACACATCTATACTACTAGAT ACTCAGGAGGCTGAAGCAGGAGGATATCTTGATCCTGGGAGGTAGAGGTTGCAGTGAGCT GTGTTCATGCCACTGCACTCCAGCCTGAGCAACAGAGTGAGATTGTGTCTCAAAAAAACA AAAAACAAAGAATAAGTAATATCTACTCATTATACAAAGTTCTCCAAGCATATATGAATA GAAAGTGAAAAGTCAGTCTCCTTCCAATCCCCATCCACCAGCTATCTAGTTCTCCAGAGA GGACTGGGACCACTGAGAGGACCTGTTTCCCACACCCTCCCAACACAGTATATTAGCAAA GCCTTCTGATCCTTGCCAATCTGACAGGTGTGGATTAAGTATAGTCTTAATTTGTATTTT ATTATGCTTAAAGTTCTGAATATTTTCTATTTTTTAATGGAATTGTAGGCTAATTTTTCC AATAGAATTGTAGAGTCTAGAGCATCTTCACATGCTAAGGAAATTCGGCCTTTTCTGTAA GTTAGAAAAATTTCCCCCACTTTTCATTTGTTCCTTGCTTTTCTCAGTGGTTTTTTTTTT TTTTTTTTTTTTTACATAGAAGGTGTTAAATGAATTTTCGTGGAATAAATAAGTTAGTGA ATGAAGTAAAATGTATCAATCTCATATCGTTTCTCAGTTTTCTGTCATATTTAGAAAGCC CTTCTTCACGCCAAGATTTTTTAAATTCCCTGTTCTCTTCAAATATTTTTAAGAATTTCA TTTTTTGAATTTTTCATCGTGGAGAATTTCAAATATACAATAGATACAGAATAGTGTAAT AAACCCCCTGCCCTGTACCCAGGACCCAACTTGAACAAATTATCAAGTCATGTTCCATCT GTTTCATCTCTATCCTCATCTATGGGTTTAATTTTTTAATCCAAGGGGTATTTATTTTGG CATAAAGAAAAATACATGGATTCAACTTAGCTGTTTTTTAGATGTTTATGCAGTTATTCA AATACTATTTATTGAGTCCTCCATCTTTTCTTTACAAACTTGAAATGCCATATTTACTAT ACATTCAATTTCCATATTTGGAAATATTGGGGTCTATTTTGGAACTTTTAATTCTGTGCC CTTAAACTACCAGTTCATGTGACAGTGCCATACTGTTCTAATTACTATCGTTTTATAACA TGTCTTATATGTTAGAGCTAATTACTCTCATTTCTCTTTTTCAAAATTCTCCTGATTATT CTTATTTTTTACATACTGATTTTAAAATCAGCTTATTTAGTTTACATATAAACACAAGTA TTGTATTTTATTGGGGCAGCATTAAATATGTAAATTAAGAGAGAACTGATTTTACGCTGT TGTATCTTCCTATCCAAAATATCCTAAGCATTTCTATTTAAGTCTTATTTTGGAACTCTC ATAGCAGGTTTTGTTTTGTTGTTAAGTTGAAGTACAGTTTCACACAATGAAACGCACAGA TCTTGAGAGGAGTTCACTTTAATGGGTCTGAAAAATTAATCGCAGAGTTTAGATGCGTAT TTTCAAGTGTGTGTGTGGTGAGGGGTGAGGAAGGACAGCAGCATTTTAAGTTTTCTTTTT AAAGACCTTGCACATTTCTTATAAAGTTTGTTCCAGGATATGACTTCCACACATAAAATG GAAATTAAAGTTTTTATTTCAATCTTAATAGAAATTATTCCGACTTTATAAACACACCAC TGATTACCATCCATAATACACACACACATACACACACACACACACAGAGGAGGCTCGGGT GGGAAGGTATCCAGTCAGTCTTTTTATTGTGGGAATGGGAAGAAATTTCTGAGGATATGT AGTAACTGCAATTAGGAAAGTCTCTAAGCCCAGAAAATTAGGGAAATGGGGAAAATGCCT TTTATGAATGAGTTCATTAAGACAAAGGAATTATTTAGAAGTCTCTCCTTTCAGCTGACG AAGGAGATTAAAATTACAGCTGAGTTGGAACACTAACAGGCCAAGCCAGCAATGCCACAG GCCCCGCAGATGGGGAATAGAAAATGAAAGGACAACAATAACTTGGAAATGAGAAAAATG ACTGTGAACTGGATAAGGCACAAATGAGGACATGTGGATGAAGTTTCTCTGAAGTTTTAA AACCGTATCTGTGAAAATATATTGAACTCTTCCCTTAGAAAAGTTGAAGCAGAAACTTGC AGAACCATCCCCAGGGCATCTTAACTAGCATTGTTATGATTTGGATCAAAGTTCATAAAG CCAGATTCCAGAAGCACTCTGAGTGACTTAATTGTTTTGGGAGTCCTCCCTTAAACAAAT ACATTGTTCAACTGGAAAAACAAGCCCTAATTTTATAACTAGAACCTGCCAGTGTGAAAC ATATGTCTTAAATATAAGTAACAATTCTAAGATTGTTTTGTCTTCCGATGACAGGATAAT TTCCAGATTTTTTAAATGTTATAATACTGATAATTTGAACATGATGAACTATGTCTCCAC TAAGATAAAGGAATAATTTACTACTTACTCCTTTTTGGCAACATGAGCATATGAAAAGCC AAATGATGTAGAACATGCAGCAATGAATGGAGAATGGGGACTTGCTTTGCTTTACAACCT TTTTGAAGAGCGTATTGTTTTATTTTAACTTTATTTTATATTTGTATTTGTATTTTAGAT GTATATAATACACAAAAATATAGAACATTACCTATTCTCTACATTTTAGGAATGAGGTTG AAAACATTCCTGTCCCAGAGGAGAGAAATTGGACGAAGTCCAAATATGGTGGCCACACAT TCTAGTACCAATCAAAAGGGCAGATTCCATACCACAGCCCCAGACACGTGTGAGCATGAC ATTTTGAGGCATTTCACAATGGATATTGTAAAACTGGCATATACAATCCTTGGTATAAAA AATAAAGTTACTAGAAGGAACCAAGCCTACTAAACCCTTGACTTTTGCTCAGTGAAACTG ATTTTGGACTTCTGACCTCCAGAATTGTAGGAGAATAAATGTGTGTTGTTTTAAGCCACA AAAATATTTTTTAAATAACATAAATTTTAAAACACAGTTACTAATCAATGGTCAACAGAC ATAGCCTCATGCCATTTTCTTGTGATCTGTGATACGCATTTATCTGAAAGGTGATTGAGT GTATGGAGTGCATCTACGACTACAGAAGACAATGAAATAAAATGAATTAATAAATACTTC ATTCAAAAATTGTTATGGAAAAACTCCTATGAGCCAGGCACTGTGCTAGGTATTGGGATA TGACAAATAATATCTTATTCTTGAGTAGTTTATATAATACAGGAAGATTACTGCTTTAAT GAGGACTCTATGGAAGGCCAGAGATTAAAGAAAAAAAGATCACTCTGCTCTGTCTGTATG ATAAACAAATCTTTGACTGTGGCTTCATAAAAACGTTACTCTAAAAAAGTAAAAAAACAG AAATATAAACACACAACAAACCCATAAATAAACAGCTCTCTTTGGGAAAGGTAAGACAAC TTCAGGATTGCAGGCCATGGCCTTGGTGGAGCTAAAAGGTGTGTTCCCAGAGCCACAGTT CTGTGCCTTCTCTTATACACAGCAAGAATCAAATTAGAACAAGTGAATTATTTGTGTCTG CATCTGGCCCTTTTGTTCTGGTACAGAATTAAGAAAATCAAAGACACTGGATTGCCAGAT AATAAGCAGTTTCTTTTATCTGTAAATTGAATTTACTTTTCCAAGTTTTATGCTTATTTT ATGTTAAATATGTGCTTGATAAACAAAATATGGTATACTTTTTTTAATTAACACTTTTTT AAAAAGGACCTACTACTAACAGGGAAATAGCTTATTTTTCTTCAATGAAAAAGCTAAGGC AGTAAAAAGGGTACCTACAAAATAAAAAGCGCTATTATAATGGGAAATATTTTAGATGTA CATGTATTCATTCACTTATTCACAAATTCAACCAACATTGATTACTTGCTATGTGCCAGA TACTGTACCTGTGGAACATACCTTTGATTTATGTGCTTGATGAATAATCTTTAGTGCATC TGAAAGAAAAAAGCAAGTTATCTTTTTACACAGTTTATTCTAAACTTCTTTTCAAATTAT TAAAATGGGTGGAGGGTGGCTACGAAATTGAGAAATGTAAGTCCTTGTTTTATAACCAGA CTCATTTAGAAATATACTATACAGCAAAAGAAAAATTACTTCTGTAGATCATTAAAACTG AAGTAAAAGATCTTTATCTTTTAAAGCCTTGGTCTTTGACACACAGCAGTGTGTGTGTCA GAACTTTTTGTCAACTCAGCACATTTTTTCTTAGAATGGAAGACAAGCAAATCAGATTAC TGTACCTTGTTTTTTTGGAGTCAATACAGAACAGGATTAGCAAATAATGTAAAAAAAAAA GTCTTAAAATAGACATTAGCAAATGCAGTTCAAAAAAATCTATTCAGATGAGATATAATG ACAAGAGAGCAAATGATGATACAGGTGTTGCCACTCTCAGTATTCAAACACTGTATCTAG GACCACCGGGAATCTGAGCAAGGCTGCTAATGCCCCAGGAATATCACTATCTGTCTCTTG GTTTGCAAATACTGCACAGGCTCACACCATTTCATCTGCTCTATTCAAACCCAACTTCAC TCCTTAATTTGTTTATCTTGAAGTCAGGCTACACTGTGCACTTCCAGTAAGTAATTTCTC CACACTTGGGTAAAATTCGAACTCAGCAACAATCAGCCCTTAATTACATAATCTACACAG CCATTCAACAGGTTGAAATTCAGAAAGTTTCCGATTCTTCACTCGTTTTTATTTAAACAT TTAATGAATGCATTATGATTACAGTGTATTATTGAATAAACTCCCAAACTTAAACTAAAA CTCATTCCTATCAATCACGTTGTAACAAGGAATTCCAACAGTGACAGGAAATGAAAGGAT CTATTTTTAAAACAGACCTTATTTAACTATGTTCTCATAATACACAATAAGGTGGCTATC TAGATAAGAACTAGCACTCTGAATTTGCCCATTATTTTAAATAGTCAACTTTCAGTTATC TATTGCAATTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCTTGGCTGCAGTAC AGCAGCATGATCTCAGCTCACTACAAGCTCCACCTCCCAAGTTCAAGCAATTCGCCTGCC TCAGCCTCCCGAGCAGCTGGGATTACAGGCTCCCACCACCACACCTAGCTAATTTTTGCA TTTTTAGTAAAGACAGGGTTTCACCATGTTGGCTAGGTCTCGAACTCCTGACCTCAGGTG ATCTGCCCTCCTCAGCTTCCAAAGTGCTGGGATTACAGGCATGATCCACTGCATCTGGCC TTGTAATTTTTTATACAAGGTCAACATAATCCTCAGTAACTCTGTATTCCTAAGAAATAA AAATAAATCTAACCTAAGTAAAATATGCATATTAGGGATGTAAATAAACCATAATTGCTA AAAATAAGCTTAAAATGTGTGTAAGAAAATAAACAAAGTTGACTTTCAGCTTATCTAGTA TTCCAAATTACCTATCATGTCCTTTTTCTTACTATAGATATGTTTATTATTTGAGACAAG TGAGAGAAGCCAATAGTATTTTTAAAATAACAGGAGCTCAAAGTCTGTTGCAATCAACCT GCAAAACTATAGTCTGACCTTACTAAATATTAATCCTGTTCTATATATTTTGCTAATGAG CCTTTAAACTAGAAATCCTGCTGCTCTAATAGGTTTGGCAAACACACAATTAAACGGCTA CATATTTTAGCAGAAAAAGAAATGTTTTGAAGAGAAGTTTTTGCCAGATTTTTCTCTCCA ACAGAAAGGGGTGTGACCTGAGGAGTGGGTAAGAAAGGAGAAATGACAAACCAGCAGAGA GATGTATTACTGTCCCTTTCTGTGTTGAATAAGCTGCTTCCCTTGTTCTTGCTTCTTTCA AATAATCCTCATAATTATCACAAACAATACCTGTGGGCATTGTTTTCTTAATACAAATTC CTTGAGGAAAGCAACCTCATAAAAATATCATCTTGTATTTGTGGAGCATCACACACAGCT TTATGAAACAGAGAGGGATGAGCAGCCCACACTGTACAACAACTACATTCTTGTGTGCCC TCATGGGTCATGTCTAGGCGATAGGGATTTAAGATAAGTAGCATGCGTGGTAAATCAATA ATAGATGTGGATGCCAATTAAATGGGAGGAGGGCTCTGAGATATCTCAGGCTCTTGGTGG CAGAGAGAATCAGCCCTTTGCCAAAGGGTAGGGAGACAGTGACTGGCAAAACTGAAATCT GACTCCACACTCTTTCCACTCCCGAATACCTAACAAAGTGCCCTGTCCCGCAGACCGTGA GGTGGCAGTCCCGGATGACAATGACAGGTGAAAATAACACTGCAGCCTTTCTTGTTCAAC AGAAAGCAGAAGATTGTTAAACAGCCAAGTTCAGACAAAGCCACTTGAAGTCTATCAAAA CTCGAGTGGTTCTATAATTTCTTCACAAATAAATGTATTCATTTTTTCTGCCAATTCATC TGAATAGTATAGAAATACTAGGGCAGAAGGAAGTTAATAAGATAGAATAGTCTAAAAGGT ACATTATCTACCACAATAATGCTTAGCAACTTGGATATTCTAACGCTTTCATTATCTAAA ATTTCTTTCAAAAGAACTTACATGGAACACAGCTTTGCACATAGACATATAGATACACAC ATACACACACACCATGAAAAAAGGAAACCATATGTAACTATTCTAATTTAAAATGGCATC TGTAAGTTGATTCAAGTTTAAGGCTATATTTCAAGACATTATACTTTGAAAGCCTTGAAA GCCACAATTGAGAAGTTTCATATTTACCTTAATCATCCTTTTTATTCCTTTATCTTATTC AATATTGAGTATGTAAATTCTTTAAGCCCAATAAATCAAAGTACTTTCCACTCAGTGCCT TCAACTTCTGCTTCACTACCCCTTATAACCTCACAATTAGTTTCTGGATATTAAAATGCA TACACACGGCGAAGATTGTGATTTCAAAGGATTTTAGGTCATAAGTTGTTCTATCAAATG AGAACAGAATGAAAAGCCACTCCAAAAAAAAATCTAAGGTAATAAAAAATTTATACTTTA AAATGTCTGCACCAATTAAGAGAAATATTTATTAGGTGCATCATACCTTTCAAATGAAGT CTCAAATTCAAAGTTTGGTGAGTGTCACTCTGCTGAAGGTTAATAACTGTGCCATCTTTA TAACAAATAATGAATGACAACATCTAGCTTCTTACCTTATTACTCCATTTTTAAATCATC AATTGTAACACATAAAACTACTATATAACATGCTCAAATTATTGGCATTTAAAATGTTAA ATCCCTTCTTTTAATTCTTAGTCTTCAATCATTTTTCCTTTTCTAATTACCTGGCAGAGA AACTCGTTTTAAACACAGTTTTGGCAAACATGCTACTCTTTGCAAATACGCCACTTCCTT ACTATTACAATTCATTTCAGCAATATACTAGCATTCCTGTATTTCTAAATAAACTTCCAA ATTGGTTTTTATTTACAGATAGTCATTTTTGAAAACAAAATTTAAGTTTGTAACAAACTA ATGCAAAATTGTATTTATATATATTTTAAAAGAATAAAAAAATGGTTACCATATTTATAA TTTCTGAATGGTGGTGGCAGGTTGGTCCTTAAAGGGATATCTACAAGAGAAAGATTATTT TTTTACACAATAAGCAAATAGACACTCATAGAATATGCACAGTCTTTTGGTTCTATTCTT TTCTATCTACAGACTAAGTTACCTTGAAAAACCTGACAGAACACAGAATAAATACATCAC CGAAATCCAAGGGCCATCTATATTAGTCCATTCTCATACCACTATAAAGAAATACCCAAG ACTAGGTAATCTATTAAAAAAAATGTTTAATGGACTGGGGAGGCCTCACAATCATGGCAG GTGAAAGAGGAGCAAAGGCACATCTAACATGGCGCCAGGCAAGAGGGTCTGTGCATGGGA ACTGCCCTTTATAAAACCATCAGATCTCACGACACTTATTCACTACCGTAAGAACAGCAT GGGAAAAACCCACCCCCATGATTCAATTCTCTCCCACCAGGTCCCTCCCCTGACAGGTGG GGATTATGGGAGCTACAATGCAAGATGAGATTTGGGTAGGGATACGGCCAAAGCATATCA CCATCTAAAATATTAGAGCTATTGACAAGATGTTGAGTTGTTACTATCTGAACTAAGACT TCAGTAACACTATTAAAAGAATGTTTAATTTCATTAGACAACAGTATCTATGTATAGTTA AAATATATACTAATACACTTGTGTGAGACATATATATATATATATAGCTGATGTTTGTTT AGCATATGAATCTGAGAGCCCCTTATGGGTCTTTGGCCATTAGTGGAAACCAATGATCTA GAACAATCTTATTACTCCACCAAAATTCATATAACCAACAAAATAACTCCTCTAACTCCT CAAAGACAACAAAACACAGTAAATATTCTTTTAAAAACATATTCCAAATGCCAGTACTAA TTTTAATTAATATCTGCTGGTACAACACCTAACAGAGAAATGTGTGTATATATGTGTATA TATATATATATCTCAAAATTACATATGCACATACTCCTTGACCTAGCCATTCCACTTCAG AATCAATGAGTGAATGAACGAATTTATTGATTAACTGATTGACACAGGGTCTCATTTTGC TGCCCAGACTGGAGTGTAGTGGAACAAACATGGCTCACTGCAGCCTCGACCTCCCAGACT CAAGTGATCCCCCTGCATCAACCCCCCAAGTAGCTGGGATTACAGGTGCATGCCACCGCA CCCAGCAATTTTTTGTATTTTTTTGTGGAGATGGGGTTTTGTCATGTTGCCCAGGCTGGT CTCAAACTCCTGAACTTAAGCAATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACA GGCATGAGCTACTATGCCCAGCCGGAAATTTATTATCATAGAACTATACTACACACGAGT GTGTGTAAAATGACATTCATAGAAGGGTATTAACTGCAGCATTGCTCACAGCAGCAAATG TTAGGAAAAGTCCAAATGTCCTTCAATTAGGTACTCGTTAAGTAAATCATAATATGCCCA AACAATGAAAAATACTTTTCAACTGTTAAAAGAAAAAGAAGGAAGCTCTCTACTAACATG ATAAGATCTTCAAGTTACATCAAGGCTAAAGAGATATGAGAGAACATTATTTTTAGGAAG CTACCTTTTGAGTAAAAAGGGGGTAAAATGAGAATTTATGGTGGGATTTGCTTGTACTTG CTGAGTGGGGGGTGGGGAGGGCAGGGGGGTGCTGCACTGGTCAGACAGAGACCAGAAGGG TAAAGGAGACTTTTCACTATATTCCTTTCCACATTTTGATCTTAAAACCACATGAATGTG TTACCTACTAAAGAAAAGTAAAACAAACAAAAAATATCCACGTATCTAAATTAGGAAATG TGAAGGTTTTTGAGACAGGGTCTTGCTCTGTTGCCCAGGCTAGAGTGCAGGGATGTGATT ATACTCACAGTAGCCTTGACCTCCTGGGCCCAAGCGATCCTCCCACCTCAGCCTCCCAAG TAGCTGGGACTACAGGCGCTCAGCACCATGCCCATAGTCCCGGCATTTTTTTTTTTTTTA ATAGACAGGTTTCACTAGGTTGCCCAGGCTGATCTAAAATTCCTGGGCTCAAGCAATCCT CTCACCTCGCCCCGAAAGTGCTGGGATTACAGGCATGAGCCACTACACCTGGTCAGGAAA TGTGGGTTTTTTTAAAATGCTTTTTCAAGATCAAATACGTATCAAATTAAAATATAATTG ATTAATTTATGTTACAAGCATTTAAAGCACCTACTACCAGGTATTCCAGGAACAGAGTAA AAGAGGAGCTGCCCACTCATGACAGCGTGTGCTCCAGTGGTGAATGCTGTAACAAAAGTA CGTTTCCAGCCAGTGCTATGGTCCTAGGAGTGTGGTCCTCACCCCGGCTGCACGTCAGGA TCACCCAGCCTGGCACGAGTGGATCTGACTCACGGTAGGCTGGTCCCAGGCAGAGATATT TAAACACAAAACAAAACAAAACAAAACAAAAAAAACCCTGAGATGATTCGTACTCAAATT CACCCAGAGGCCAGACAGGTGACAACAGGTAAGTGAAGCAGGTCAAACAAGGAGGGGCAG TGAGATCTGAGAGCATGCGCCCATCAAAGGGGGCTCTGCCAGTCAGTGCTGACTGATCAC AGTGCTGTAGGAACATGAGCCTGGAGTGGCCACACCTAAAGATTTAAATGGCAATGCTAC AAGTCTAGGGTTTTAGGTGAAATTTCTTGACTTTTAAAACACTATAGGCCAAAAGAAACC TCTCTGGAGGCAGGATTTGCCTGCCAGATACCAATTTGAAACCTCTGGCTTAGGCTTACC AGAGCATATGTACTTCATTTTATTCTTCTTGTGTCTCCATTATTTGTGAATTATGGGCCA AAGCAGTATTCATTCAACATCAGAAAGGAGAATTAATTCCATTTAATGTATTGACATTTA TATTTCCTGAATTAGACAATGAAACTCCCTGAAGAAAGCCGTGAGGTGAAGAACAGATGG CCCCATGAAGCTATTATCATTTAGAGATGTCTACGACTGAAGAAATCAAATCAGTCTTAT GTTCAATCCAGACTTCTGAGAGAAGAGACAACGACCAGGACACAGCGAGCACCTATTCTC TTCCTGCCTTTACATCTTAACTGAAGTGCCATCTCCTCTGACAACCCTTCTAAAGCGGGG GTCTTCTCTGATATTGTTTCCTTCATAACAGGTTTTACAATTATAGTTTTGTCTTTTAAC TTATTTTTGTCACTATTTCCTATGAATTTATAAATTCCTCGGGATGAAAACGTGGGCTGT CCTCTCAAAACCTAGGACCATGTCCGGCCCATAACAAATTATCACAAACTGCTTCCATGA GGGCAGGGACCACAGCCTGTTTTCTTCATTGTGTTGTCAGAACCTAAAATAGTGCCTGGT ACACAGCATGTGCTCAAAATATTCATGAAAGAATACATATAATTTAATGCCTACAGTTGC CAGTGGAGAACACTGAGGTCTCAAGAAGTGCCTGGTCAGCCCAAGGTGTCAAGAGCTGGG ACCAGAACCCTGCCCTCTCGACTCCCCTCCTGCAGCACTGAGAAGGGTGGGAACTAAAGC AGTTACCTTCCACAGTGGCAGAAAGACAGATTAGACATTAGACACACTCCAGTGAGATAA GAGCTTTAACCAAAATACATATAAAGATGCCTGCAAAGGAACTGGAAAAAAACAAACATG TTCTTTATGCTAAAGGTCATTTTTAATCTTGCGCTATTACAAATAAAGCTGGGAACATTC ACATGGAGGAAATTACTTTCATTCTCACAGGCACATACTGTCATTCCACCTAGAAGTGGA ATGGCTGGATCATACAATAGGTATATGTTTAGCTTTCTAAGAAATTGGTGGCCGAGTGCA GGGGCTCACACCTGGAATCCCAGCACTTTGGGAGTTCAAGGCAGGAGGATCGCTTAAGTC CGGGAGTTCAAGACCAGCCTGGACAACATAGCGAGACCCTGTCTCTACAAAAATAAAAAT TAAAAAAAGACACACCTGCAATCCCAGCACTTTGGGAGGCCGAGGCGGTTGGGCCACCTG AGGTCAAGAGTTCGAGACCAGCCTGACCAACATAGTGAAACCCCATCTCTACTAAAAATA CAAAAATTAGCCAGGCGTGGTGGCGGGTGCCTGTATTCCCAGCTACTCAGGAGGCTGAGA CATGAGAATCGCTTGAACCCAGGAGGCAGCGGTTGCGGTGAGCCGAGATCTTGCCATTGT ACTCCAGCCTGGGCGACAGAGCAAGACTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGACA TGATGATGTCTGTAGTCCCAGCTACTCAGGAGGCTGAAGCAGGAGAATCACTTGACCCAT GAGTTAAGGCTGCAGTGAGCTATGGTTGCACCACTGCACTCTAGCCTAGGGGAGACAGAG CAACACTGCCTCCAAAAAAAGGAAAGAAATGATAAATCATTTTCCAGAGTGGCTGTTCCT TTTAATATTCCCACTAGTGGTATATGAGAGTTCCAATTCTTCCACATCCTAGCCAAAACT TCCTATGGTTACTCCTTTTAATTTCAGTCATTCTTATGGATGTGTTGTGTAATCTCATTG TGGTTTTAATTTCCATTTCACTAAAGACTAATGATGAGTATTAATTAATGTGCTTATCTG CCATACATACGTCTTCTTTAGTGAAGTGTCCGTTCAAATATTTTGCCCACTTTTAATTGT GTTGTGTGTCTTATTATTGAGTTATAAGAGGTTTTGGTTTTGGTTTTAATTCTTATTATT CTAGATAATAGTTCCTAATAGTTCCTTGTTGGATGTATGTTTTACAAATATCTTCTCCAC ATCTGTGGTTTGGTTTTTCATTTTTTTAGTATATTTTGAAAAGGAAAAGTTTTTAATTTT GCTAAAGCCCAATTGATTTTTGCTTTTATAGTTTATGCTTATTGTGCTGTATTTAAGAAA CTTTTACCAAAATCAAAGTCTCTAAGGTTTGTTGCTGTTTTCTTCTAGATGTTTTATAGT TTTACCTTTTACATTTAGTTCTTGGCCAATTTTGAGTTATTTTTGTATATGGTAGGAGGT AAGCATTGAGGTTCATTTATTTGCATATGGCTATCCAATTGTCCTAATACCTTGCTTGGG AAAATTACACTCTCCTCAAAAATACCTTGAGCAAAAATCAATTTAACACATCTGTGTGTC TGTCTCTGGACTCCGCTTCCATTAACGTATATGTTTATCTACACACCAGTATCACATATG CAGTACTTGATTACTATAGTTTTATAGCAGTAAGTCATGAAATAAGGTAGTGTAATTTCT TCAACTTTTTTCCTTCTTTTTGTGAGTTATGACGATTTTAGGTCTTTTGCCTTTCCTTAC AAATTTTAGAATAAGTTTGGTATTATCTGAAAGGAAAAAAAAAAGCCTGCCAGAATTTTG ATTAGAACTGGAATCAATACCACAGTTTGAGGACACATGACATCTTAACAGTTTTGAGTT TTCTGATCCATGAACACAGTATACCTCTCCATTTACTTAGGTCTCTAAATTTCTCTCAGT GATATTTAAAGTTTTTAGAGTAAAAGTCTTACACTTCTACCAAATGTATCCTAAGTATTT CAGGTTTTTTGATGTTTTATCATTTTTTTTTCAGTTTCCCACTGTATATTGCTTGTAACT AGAAATACAATTAATTCTTGTACACTGATCTTATATCTTAATATCTTATAACCTTGCTAA GCTCAGTTTGTAAGTTCTGGTAGCATTTGTATAGATTTCATAGGATTTTCTGCATAGATA ATCATATTGCCTGTGAATAATGACAGTTTCACGTCCTCCTTTCAAACAGGGTTGCCTGTT ACTTCATTTTCTTGCCTTAATGAACTGGCTAGAACTCCAGTACAATGTTGAATAGCAGTG ATGATGAACAGATGTCCCTGCTTCCTTATTTTAGGAGGAAAGCACTCAGTCTTTCACCAT TAAGCATGATGTTAGGCAACAGTTTTTCATACTCTTCATCAGGTAGAGGAAGTTCCTTTT TATTCCTAGCTTGAAAAGAGTTTTTAGCAGGAATGGATTTTGGATTCTGTCTTCAATTAA AATAATCTTATAGTTTTCTTTTCTTTACTATTAATATGATGAATTACATGGATTTTTTTT TTTTTTTTTTTTTTTTTTGGTGGAACCAGCATTGCATTCTTAGGATAAACCCTACATGGT CATTGATATAGTTTGGATGTTTTGTCCCCTCCAAATCTCATGTTGACATGTAACCTCCAA AGTTGGCGATGAGCCTAGTGAGAGGTGTTTGGGTCACGGGGGTAGATCCCTCACAAATGG GTTGGTGCTCTCCATGCTATAATGGGTGCGTTCCTCCTCTATTAGTTCACGTGAGATCCG GCTGTTTAAAAAGAGCCTGATATCTTCTCCCTCTCTCTCTCTCTTGCTTCCTCTCTCATA TGGCATGCTATGTGGCATGCTGACTTCCCTTTGCCTTCCACCATGGTAGTAAGCTTCTTG AGGCCCTCACCAGAAGCACATGCCAGCACTAAGCTTTGGGTATGGCTTACAGAACCGAGA GTCAAATAAATCTCTTTTCTTTATAAATTACCCAGCTTCAGGTATTCCTTTATAGCAATG CAAACAGACTAACAGAGTCATAATGTATTATCCTTTTTAAATATTGTTGGATTTGATTTA CTAAAGTTTGGGCAAGAATTTTTACATCTCCATTCATGATGGATATTGGCTGGTAGCTTT ATTTTCTTTCAACAACTTTTTCTGGTTTGGTATCAGGGTAAGGATGACCTCAGAGAATGA GTTGAAAAATATTCTGCCCCCCTCCTTTTTTTTTTCTTAAGAGACAGTATCTCGCTATGT TGCTTGGGTTGTTCTCAAACTTCTGGCCTCAAGAGAACCTCCTGCCTCAGCCTCCTATAT AGCTGGGATTAGAGGCAAGAACTATCGTGCCTGGCTCCCATCCTTCTTCTGGAAGAATCT CTGTAGAATTGAGATTATTTCTTTCTTAAAAATATGGTAGAATGTACCAGTGAAACCATC TGGGCCTGGAGTTTTCTTTGTGGAAGTATTTTTTAACCATAATTCCTTTTAAAATACAGA GTTGTTCATGCCGTTTCTTTTTTAGTGAGCTTTGATAGTTTGGGTCTTTGAAGCAATTTG TCCTCTTTATCTAGGATACTGTACTTATTAGCATTAAATTGTTAAGAATATTCCTTTATT ATTCTTTTAATATCTGCAGAAAGTCTGTAGTGATATGACAACTGTCACTCCTGATACTGG TAACTTGTATCTTCTCTATTTCCTGATCAGTCTGGCTAGAGTTTACTCAATTTTATTGAT CTCCAAGAATCAACTTTGACTGTTATGGATTTTCTCTATGGTTTTTCTATTTTCTGCTGT GATCATTATTATTTCTTTTATTCTGATTATTTTAGGTTTCATTTGCTTTTCTGTTTCTAG TTTCTTAACATAAAGACTGAAATCATTGATTTGAAACCTTTTTTAATATTTAGGTGTTTT AGTACTATAGACTTTCTTTTAAATACTATTTTACATGCATCCCACAAAATTTGAAAAGTT GTATATTCATTTCCACTCAGTTCAAAATACCTTCCCTTTTGATCTCTGCTTTGACCCTTA GGCTATTTAGAAGTGTGTTATTTGGTTTCCAAATATTTGGAGATTTTTCCAGAGATCTTT CTGTTATTGATTTCTAATCTAATTCCATTATGGCCAGAAAATAGACACTGTCTAATTTGA ATCCTTTAAAATCGATTAAGACTTGTTTTATAATATGAAATCTGGACTATTCATAAACGC TCCATGTGCATTTGAAGGAAATGTGTAAATTCCACTATTGTTGGAAGCAAGATTCTATAG ATGTCAATTCAGTTGATTGGGTTGCTAGTGTTTTTAAGTTCTCTTGATCCTTACTGATTT TCTATTTGTTCCATTCCTCTATTTCTTCCTGCAGTTCTATGAGTTTTTACTTCATTTATT TTGAAATTCTGTTGTTAGGTGCATCGTTATGTCCTCTCAGTTGATGCCTTTATCATTATG AAGTGATAGTTTTATCCCTAGTAATATTTTGCTCTAAAATCTACTTCATCTGATACTAAT ACAGTCCCTCCACTTTTCTTTGGATTCATATCAGCATGGTATAACTTTCTCATCCTTCTA TTCTTACTTGATTTTTATCTTTAAAGTACATTTCTTGTAGGTAACATATAATTGGGACTT CCTATTATATGTCTGTCTTTTAATTGGGGTATTTAGACCATTTACTTTCAATGTGATTAT TGATATGGTTAAAGTTTGCTATTCTTTTAAATTTGTTCTCTATTTCCTCTTTTTCTATCT TCTTTTGGATTGTCTATTTGACAATATTTTATGATTCCATTTTATCTCTTTTTTTAGCTC ATTAGCTGTAACCCTTAGATTGTGGGGTTGGGAGGCAGGAGTTGCTTTGAGGTTTACAGT AAACATCTTTATCGGTCTACCTCCAAATGATACTATAACACTTTGTAATAGCAAAAGATT CTTCCATTTCTCCTCTGCTGGCCTTTGTGCTACTGCTGTCATAAATTTCCCACAAAACCC ACAATACGTTGTTGTTGTGTTTCTTTAAATGGTCAAATATTTTTTTTAATTATTTTCAAA ATAAGAAAAAATATTTTATATTTATTATATTTACCATTTCCAGTACTCTCTATTTCTCTG TGTGCATCCAGATTTATATCTGGTATCATTTTCCTTATGCCTGAAGAAGGTCTTCCAACA TTTCTTACAGTGCAGATCTCCAGGTGATGAACTCTTTCAGCTTTGGTATGTCTGAAAACA TCTTCATGTTGGCTTCATTCCTTAACTGCTTTAAAGAAGTTACTCCAGGCCAGACACAGT GGCTCACATCTGTAATCTCAGCACTTTGGGAGGCTGAGGAGGGCAGACCACTTGAGGTCA GGATTTCGAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACTAAAAATACGAAAA AAATTAGCTGGGCGTGGTGGCACATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAG GAGAATCGCTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACT CTCCATCTCAAAAAAAAAAAAAAAATGTTAATCCAGTATCTTCTTTCTGGCACACACTGA TTCTGATGAGAAGTTGGCTGTCAATTTCATCTTTGTTCCTTTTTATGTAATGTGTTCTTT TTTCTCTTGCTGTTTTTAAGATTTTTTTTCTTTACCACCAGTTAAGCAGTTAGATTATGG TATGCCTTGGTGTGGCTTTCTTCATGTTTCTTTTGCTTGGGATTTGTTGAACTGCTGGGA AATGTGAGTCTCTAGTTTTCATCATATTTGTAAAATTTTCAATCATTATTTCTTCAAATA TATCTTCTGTCCCCCGTCCCTCTCTCCTTCACTATCTCCAATTACATGTATATTTGGCTA CTAGAAGTTGTCCCATACCTCCCCACTGCTTTATTTTTTCCAGTCTTTTCCTGTGTTTCA TTTTAGATTGTTTTGTTGCTATGTTTTCAAGTTGACTAATTTTTTTCTCCGCAGCATCTA ATCTGCAGGCTAATCCTGTCCAGTGTATACCCATCTCAGACAATATTTTCAATTCAGGTA TTTTTAAATATCTTCCATTGCTAACATGCTCAATCTTTCCTCTAGCTTCTCGAACATTTT GCAATATGGTCATAATTATCTCCATCATCTTTGTTTACTAATTTTATCACCTGCAATATT TCTGGGTTGGTTTCAATAGACTGATTTTTTTTTTCTGCTCATTATGGGTCATACTTTTTT GCTTCTTTGCATGCCTGTTAAGTTCTGATTTGATGCTAGACACCGTAAATTTTATCTTGT TGGGTGCTGGATATTTCTGTATTCCTGTAAGCTTTCTTGAGCTTTCTTCTGCAACACAGT TAAATTACTTGGAAACAATCTGATCCTTTCAAGTTGTGCTTCTGAACTTTGTTAGGTGGG ACCAGGACAGAATTCAGTCTACAGCTAATTTTGCTCTACTACTGCAGCAACACCCTTCTG GATACTCTGCCCGATAACCTGTGAATAACAAGGTTTCCACTCCAACAGGTGGAATAAAAA CTATTCCCAGCCCTGTAGGAGCTCCGAGCATTTCTCATTCTACTAGTTTTAGGTGGTTCT TTCCCAGGCTTCCAGTGGTTTCTTTACTTGCTTGCACTGATCCATACACAACTGAAGACT CACACTCTGCATATCTTCAAAGATCCTCTGCAAATCTTCAGAGCTCCCCATCTCTCTGTG CAGCTCTCTATATCCCTGTACTCTGCCCTGTGAACTCTCCAGGGTCCACTCCAGACTGCC AGCTCTGACTCCTAAACTCATGGAACCCACCAGCTTTGCCTGAATTCCCTCTCCCCGCCC TGTGGCCTGGAAAGTGGCACAATCATAGGGGTCACCATGTCTGTTTCCCCAATCCCAGGG AAATGATTGTTTTATATATTATACATAGTTTTTTTAGTTGTTTAATGTAGAAGAGCAAGC CTGGTACCCTGGTCCCACTCCATCTTGGCTGAAAGCAAAAGTTTATGACGTATCTATTAT ATTCTGAAAATTATTTCCCACTTTGCACTGCGTTTTTCTTTCATTTTATGTTTTCCCACC TTTGAACTTAAGACTTCAGAATGTTGCAAAAACTAATTTAATATTTCATTAATAGAAAGG AAGGTCACGAGAAGGTAACCACTAACTTTTCTCATACAATTAAGTCTCCATAAAAAAAAA ATCAGTGGAAAAATTTAGGCAACTTAACAAATATACTACTGAAAATTACAATGCCCCAGG GGAGTCTGAAATGTTAAAACACACATTTCAATACAAAAATCAATAAAGTCTAGAAAACCA TTGAAATATCAAGAGGCAATAAAATAATTCTTTGCCTCACAGTAAAGGCTCTAAAAATAG AAGTGGTACAATTTGTAACTTATTATTGGATGCTGGATCTACATTAGAAGACCTTTGAGA AAGCATAAACACCTAAAGGAAAAAAAAAATAAAACTAAGCCAATGACTAATCTATATGGA CAAAGAATACCAAACACCTAATAATCAAAACTATGCACCAACATTCAAACCTGATAAGGT ATCCTTATCAGATATGATGGTAAGATTCAAAGGTTAAGCTATATGCTTTTTACTTTAATT ATAAAATAATCTAAATTATAGAAAAGCACAGAGTAGAACAAAAAATTCACTTAACCCACC AACCAGATTTTACAAATGTTAACATGTAGTCATATTACTATAGATCCTTTATTATTTTTT TTAACTAAGTAAAACAATCTGGATGCAGCTAAAGCCTTTCTATCTTTTGCCAGTCCCACT GTTACTCCCTTCCTAGAAGAAACCACCTGCCATCCCTAGGTTAGCACACCCGCTCTGTTG TTTTACTCTCGTTCCAAAGACTAATAGCCAGGGATGATAAAAATAGTTTTGTTTTGTTTT GTTTGAGTCAGGGTCTTTCTCTGTTGCCCAGACTGGAGTGCAGTGGCACAATCAAGGCTC ACTGCAGCCTCGACCTCCCAGGCTCAAGCAATCCTCCCATCTCAGCCTCCCAAGTAACTG GGCTACAGGCATGCACTACAAAGCCAGGCCAATGTTTTTACATTTTTAGTACAGATGAGG GTCTTGCTATGTTGCTCAGGCTGGTCTCGAACTCCTGCATTCAAGTGATCCTCCCGCTTT GGCCTCCCAAAGTGCTGGGATTACGGTGTGAGCCACCACGCCAGGCCAAGTATTATTTTG TGTATTAAAATTATAAAGTACTTAAATTAAAGAATGCGCAGCACATCCTGTAGTAGAGTA GTAAAAACAACAAAGCATTGCCTTAACAGTATGTTGAAGGAACTGCCTCACGTGATAAGG CAATAATACATTATGACTGTGCTGCAGCCACATTATTGTATTCCTTTCAAAAAAAGAGAG GCTTCAAGGGACGGGTTCTCTACAGAAGAGTGCCAGATAATACATGTAGAGATAATCATA GAATTAGAAAAATCACAATTTTTCAACCACCAATGATTCAGATAAGGATCATCAATAAAT GCTAAAACCATAAGAAACAAGATATGTAAATGGTCTCAATGTTGATCACTCCATAGACTA CTTATAAATTAGAAAGACACTTTAACATCAGGAAAATCTGGTGGATGGCACCTTTAGCCA AAGGATTTAAATCTGTATCACCAATGAAGGCATAAACTGACATTCAGTGTTTCCTGATGT GATGCAACAAGGAGGAATCACCTACATCAAGGCCAGCAAACTAGTTTGGTAAAGGCCAGC GAGTCAGCATTTTAGGCTTTGTGGGCCAGTCTCTGTCTCTGCGACAGTCTGTCACAACTA TTCAACTCTACTACTAAATCACAAAAGTGGTACATATATGGTCCACAGACTGTTGTTTGT TAACCCCTGACCTACATGGTAATCCTGCCAAAACTGCTTAACCCGAACCTAATCATGAGA AAACAATCTAGACAAATGTAAATTATGTAACATTCTGTAAGACACTGGCCTAAATTTTTC TTTAAGAATCAATATAATGAAAAACAAAAGGTGGGGGATTGTTCCAGATTAATGGAGATT AGAAAGATATGACCTGTCACAAAATGACATGAAGGACCCTTCAATGCGTGTTCAATGCAT GTTTCTCTGTTCTTTTTTTCTTTTTTTTTGTACAGATGGGGTCATACTGTGTTGTCCAGT CTGGGCTCAAACTCCGAGGCTCAAGTGATTTTCCTACCTCCACCTTCCAAAGTGTTGGGA TTACAGGCATGAGCCACTGTGCCTGACCCCTTCAATGTATATTTCTAAGTAAAAGAAGCC ATTCTGAAAAGTCTACATACTGTATGATTCCAATTCAGTGACATTCTGGAAAAGATACAG AGATAAGAACAAAATCAGTAGTTGCCAAGGGTGCAGCATGGGGAGGGAAAGGATAAAGAA GTGAAGCACAGCGGATATTTTAGGCAGTGAAACTATTCTGTACGGCACTGTAAGGGTGGC TACATGACATTACCCATTTGTCAAAAACCCAAAGAACTTTGTAGCACAAAGAGTGAACCT CAATGTATGCAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGTCGGGCACAGCGACTCAC ACCTATAATTCCAGCACTTTGGGAGGCCGAGGCAGCGGACTGCCTGAGTCCAGGAGTTTT GAGACCAGCCTGGGTGGGCAACACAGCAAAACCCCGTCTCTACTAAAAATAAAAAATTAG CCAGGCATGGTGGCATGCATCAGTAGTCCCAGCTACTCAGGAGGCTATGGTGGGAGAATC ACCAGGGTCCGGGAGGTTAAGGCTGCAGTGAGCCGAGATGGTGCCACTGCACTCTAGCCT GGGCAACTGGAATGAGACTCTCTCTCAGAAAAAAACAAAATATATATATATATATATTTA AGAAGTCAGAGGATACCAGGAAAGAATGCAGGTGGTGACAAGAGAATCTAATCTATCTGT ACTACAAATGCTACAACAACCTTACTGAAGGGAGTAGAAGAAAAAGTGCTGACCTAAATA ACTCTGGCAATGAACAGATTTTGTAAGACTACAGTGCTTATGGCGAAAGGACACAAAAGG ACTGTATCTAACTGATATCAAGTTGCTTCCCATGGGGATACACTGCTATACCTGTATGCT AGAATTAAACAATTAAATAAATGGATAGCAGATGGTGGGACCACGTTTCTCACTGTTGGT ATGGGAATTAACAGATAAGCAAGGAGAGGAAGCTAGAATGACCCACAGGGTAATGGATCA GAGATGGAAAGATCAGTAAGAACTCACGTTTAATGTATTTGTATATAGATCATTACATAT AAAAATATTTATAGATATGTACATACGCACAGGTTAATACAGACACATATATTTCTTTGC CTGATCAGCTGAGACAGTTTAAAATAACACTCCTTGGCCTTTAGATATCTACCATAGAAA AAAGAAAGAAAGAAAGAACACTCTAGTAGCAATGAACACATCTAGTACCTAGATCCTGGT TTCTAACACAATTTTCCACTAAAAAAGAACTGAGACTCCTTGGAAATAAAGCTGATTCTA AGAACAGGGCATGTACAAGATGAGTCTGGAGCATCCTGTAGTACCAGAAAGTAAAAGTAC TGAACACGTGCACCCATGCACACTGAGGGCATATGTCAGAGGAGCACAGAAGGCAATTGA AAGAGCTCCCAAACCTAGCAAAATCTGAGCAACAAAGTCAAGTCTGCCACACAGAACTCC AAAGGATTTTTGTACATGGTTTATTCTAAAGGAAGGGAAGCATAACTCCCGAGTGTTTAA CTGTGATATGAATTCCTTCTGAAAAGTACCATTTGAAAAGGGAAGGAAAAAAGAGTAACT TTACAGTAGAGAAACCTGACATGACTTCAGCCACTTAATCAACGTCAATGTCAATAATCC TAAATGATGTGGAAAGCATACACCTCTGATACTATCTGATAAAATCACTCTGTGCCTCTG TGACCTTCCTCTCAAAAATCCATAAGCCCAGTCTAACCATGAGAAAAACATCAGACTGAA CTGGAAGGTTGGACAGAGCTTCCACAGTGTTCTTTTTCATAGTTGGGATGACTTTACATT TGGAAACCAGATCTAAAGTATTAGTAAGAATCGAAATGCTTGCAAATTAAGAATAATTAA AATAATTTTATGTTATCTAGATAATTGGTTTGTCTAGTATTCTGAATCTAAAAAATACAG TCATCTATAGATGGTAATATATTATGATACCTCTATGATCATAATATTTGATTAATATCC ATTTCCCAGGCCAGGTACAGTGACTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGG CAGGCGGATCTCTTGAGATCAGAAGTTTGAGACCAGCCTACCAACATGGTGAAACCCCAT CTCTACTAAAAATATAAAATTAGCCAGGCATAGTGGCGCACACCTGTAATCCCAGCTACT CAGGAGGCTGAGGCAGGAGAATCGCTTCAATTCAGGAGCCAGAGGTTGTTAGCCGAGACC ACGCCACTGCACTCCAGTCTGGGCAACAGAGCGAGACTCTGTCTCAAAATAAATAAATAA ATTTATCATACATCAGAAATAGGTTTATTATATTTATATGTAAATATATACATTTATATT TATTATATTTATATGACTTAAGGTTTTGATGACGTGATGATGCTCTAGGGCTGTGATTCT CAATGGGGAATGAATAAAATTTAACCAAAACTTTTTGGCTGAGGAGAAAATACAAACAAT TATGGCAGGTAACTAGGTTAACCTGTGGATGGCAAAACATGACTACGAAAGAAAAGAACA TTTAGAAAGCCTTGGGGAGGGAGGAGGATCGAAAAATAAAATTTAATTTAAAAAGAAAGA AAGAAAGGCAATAAAGTGTGTAAAATAACTCCAAGAGATCTTTCTTCACAATGCCCATTT CTGTATCTGTACAAAATTCCCTATGCCACTATGTCAGACAATCTCTTTAGCACTCAGCAC TCAAAATGCTAGAGCAAGATGAACTAAATTCAAAGACCCTTTTGACACGGAGTCCATCCA TTTATTTCAGAGATCCCACTCAAGCAAGTGAGGCAGTAGAGAAGAATAAAGAAGCAATTT AGTGCAGTGTTTAGTAAGAGTACATGTTTGACACTTAACATGCCTGGGTTGATTTGCAGC TTTGCCTTTTATTACCCATGCAACATCAGGAAAGTTTCATTTATTTATTTATTTATTTAT TTATTTTTTGAGACACAGGCTTGCTCTGTGGTCCAGACTAGAGTGCAGTAGTGCAATCAA AGCTCACTGCAGCCTCAACTTCATGGGCTCAAGCGATCTTCCCACCTCAGCCTCCTGAGT GCTGGCACTACAGATGTATGCCACCATGCCCAGCTAGTTTTTTGGGGTTTTGTTTTGTTT TTTTTTTGGAGAGACAGGGTCTTGCTATGTTGCCCTGGCTGGTCTCAAGCTCCTGGGCTC AAGTGATCCTCCCGCCTTAGCCTCCCAAATTGCTGGGATTACAGATGTGAGCCACTGCAG GTGGCCAGGCAAGCTTCTTAACCCCTCTGTTCCTTAGTTTCTTCACCTGTAAAATGGTTC CAACTTTAGAGGGATGCTGTGAGGATGAAATGAGATAATCTAGGTAAAATTCTTAGTATA GTACCTGATACAGAGTAATGTTTGCTATCATTATTATTATTACATATTTCAAAAATCCCT CACTATCAAACTGTTTGGTCTTTGTTATGTACACAATTCATAAAAGGCAAATCTGTGGCC CACCAACCTTTCAGAGTTCCATAGTACCTCAAATCAGATGACAAAGATAGGCTTGGACAC AGAGCCCACAACTCAGAAAAGTCTGTACCCCAAAAGTTCACCTTTTAGTCAGTGGAACAC ATTTCCCTAAGTGCACAATTGAAACAAGCAGTGGCTGTTATTCCCACTGCAGATGAAAGG TGTGAGTAGGTGGGTCTGAGCATCTCACTGTGACCAGTACCACTGCTCTGCTGGGGAAGG TATCTGTGGTACCTGGAAAGAAAAGAACACCGTGACCCTGGAAAAAAGACATCTTCCCCT GCCATTGCAGCAGCTTGAAAATACATCTTATTCTCAAGGACTTCAAGAACCTAGTCTGTA CTGTACAAAGAACATCATAGCACTTGCTGTGTCAACATTAAGAAACACTGTAATCCACAA TACACACAAAGATTATAAAATAAAAAAGTACGGATTTGTTTCTATTTCAAACTCTGACTA TGCTTTGGGTAATGACCTTTCAAAAGCAGGACACTTTCTAATTGACACTGTCAGAGACCA GGAAGTGCCCCCCAAAATATGCCTCTTTAGCTAAGGATTTTTTTTGAGCTAAAGGCAATT AAGCAGCAGCAGATGGAGGAAAGCTCTCGGCCCTCCGTTTGCCTAAAATCAGGACATATA ATAGATTTACAAAGAGAAAAGGTATCCTGCCCACCTCTCTCCCAAGGAAAACAAAGGTTA ATCACTGAAGACAACTTTAGACCCCTATCAGTCTGGAGACAGCACAAGAGAATCCACATT AACGAGCTTTACTAACTAGCCTTAGTATTCAGTTTCCCACAAGTTGTCACCCTGAGAGAT TTAGAGTTCATTTCCTTTGTCTTGTCACTTCTCTAAAATTTTACTGTTCTTTGTTGAGGA TGCTACCTAATCTGGGGGAGTGAGGAGAATGAGAGAGAAAGGGGAAGAGGAGAGAGGGGA GAGAGTGAGGAATTGTTTCAAGGTGAGCAGGTCTATGTGAACCTGCCCCAGAAAGTCCGA GGAAACTGAGAGGCTGAAGAAAGAGGCTGACATATTCAGTTTCTTAGAAAGACATATTTA ATAGGAACTTACAAACAGAAGCCATGTCTGTGTCTCAGGCTTTGGCAGGACAAGACAAGG GATCCACGCACCACTACCCCCCAGACCCAGGGCTTATATCATAGGGAAAGGGTGATCTGA AGGGATGTGTAGGGCAAGCAAAGTACAATAACATCAAGGTTGCTTGACCTAAGGTCAGGA TTTATAGTAAGTACCTGTTCTTACATAGGGAATAGTAGATAACCTGGAAATCTTAGAGGT ATCTTGAAACTGGGGCTAATGAGAAGTCAATATGGCAGATCAGTATCCAAGATGGAGTTG CTTTGGCCTCCGCAGGAATAAAACAAACATAGCAAAATGTTAACACAAGGAATCTGTGTG AAGAACATCCAGGAATTCTTTGTCTTGTTCTTGCAACTTGTCTATGAGTTTGAAATCATG TCAAAGTAAAAAAATTACATTGGATATAAAGCAATACCTTTGTCAAAAGCAATGGAACTA TACAAGAAATCTGCAGATTGCACCATATGTAAATAACACTTCAATTAAAGTAATGAAACC TTATTTTAGATGTTTTCTCAAAGTTCGATGATTGGAACACTTCAATAATTAAAAATGGAG AAGAGAAACCCATTGAGGACATAACAGAATGAAGACTAACTTCATGCATACTTCTAGTTT GAAACAATCAACTAGCACCGCCGTTTCTGTGTCTGTGACCACAATTATCAGCAGCTCTCA TGACTTCCTGCTGTACAGCCTCCGCTCCCCTCCCACCACACTTCCCCATGTGACCACCCC ACACCCTCTGTGCTCAGCTGGGTACCACAATCAGCTACACTACACCCGCTTGCTAATCAA CCTCCAAATACATAACCCCATTAACAACAAACCTAGATATTACTTTTAATTAAAAAAAAA AAAAAAGAAGCCAAAAATGACGGTCACAATCCCTCATGAGGACACAGACTATTCAGTGAG AATCCTTGAGGGAGGCCCTCTGCAGATGCCAGGGCCCAGAACCGGGGCTCGCCCAGCACC TGGCTTGGAACCCAGGTTAATCTTTCAAAGTACTTTAGGATTTGTTAAAGATTATTATTA ATGTCATAGTCAGCTATTTTTAAAAACTACTAGTAAAACAAAATGGCTTTCACATCTCAT ACCTTGCTTTAGAAATACGATAAATTCCTTTACAGTTTGGTCCAAATTCACTCCGTGATA CACTACAGGTTTGAAATTGCGATGTTCAAAGGAACGGATGAGGCGAACTGTGATGGTCAC TTCTCCAGGAGCCATGTGAAGAAATTCCTGTGGCAAGAGACATGAGAACCATCTAAATGA AGCCAGCTCACAGTTGTCTACCAGCACCTAGCCTGCATCTCTATCAGCTCTCTGGCACCA GCCCCGCTCTTCCATGCTGCATGATCACTGACAGAGTTCCCAAACAGAAGCCAGGTTCCA GAGTCCCCAGAAGGGTCCCAGTGATTATACCCACCTATCCACTGCAATCCTGGACAGCTC TGTCACAGTCACAGATGTTCTGACCAGCAGAAAACTGACAGAGTACAGAAGATGAACCAA AGTAACACAGGGGCATGTGTACGTGTGGAAACAGAGAAGCAGGACGGCCGAACACAAACA CACAGCAGACACACGCCTATTGTGGGTGCCCTATGTCCGTGGGCCCCTCAGCTGGCCCTG AGATGGAAGCACATTTACATTAGAATCAACTATCAACAGACAGCATTTCAATTTCATAAA TGCTGCCAGATTTCAGGGCTTATTTAATTATATACGATGGTGTTACCGTCTTTCACATTA CTAAAGCTGAGTATGTATAGTTCATCCTAAAACTAAGTACTAGGCACATGTACCAGGTCT TAATGTTATCTCATTTAATTCATTTAATTCTCTAAACAAAACATGAAGCATTTTGCCTCA TGGTTTCGTGAGAGAATTAAATGAGATAACATTTTAAAGATGAGAAGACTGACTTGGAGA GATTGCATAAACTGCCCAAAATCATGAAGCTGGTAAATGATGGAGTCAGGATTCAAGCAT CAATTTAATTGCAAAGTTCATGCTTTCTAATACACACACACACACACACACACACACACA CACACACACACACACACAAATTGGAAAACCACCCCAAATTATTTCCTCCAAAAAATGTCT GCACAGTTGCCAATGTTTTTTTCATGCTTAAAAAATATTTTTGTTTTGAAATATTGTAAG CAAACAGTTAAAAAAAAAAAAAGAACTTGCTACACTACCCTGTCAAATCTTAACATTCTG ATGCATTCTGAGTCTTTTAGGAAGAAAACACATCAGAAGCCCCATGTACCCTCCCCAATT CCATCAGCATTTTCTGCCCTGGGACGACAGAGCAGTGACTCGCACACACCATTCCAATAC ATAATTTTACACTCTAATTCATATCATTTGAATCTACAGAAAATAGACTATTATGCACAG CAGTAACAACACTTTCTATATTTTTTTTAATCTTGTTTTGTTTTGTTTGAGACAGGGTCT CACTCTGTCACCCAGGCTGGTCTCCAACTCCTGGGCTCAAGTGATCCTCCTGCCTTGGCC TCCGGAAGTGCTAGAATTATAGGTGTGAGCCACCATGCCCAGCAACACTTTCTGTTATAT ATCAGCAATGCTTACATGCCAGATACTACTCTAAGTGCTTAGCATTCATTAGATCATCGA CTGCCCACTCACCTCCAATCACCCTGTGAGGTTGGTAAGATCATCTCATACAGAAAAAGT GAAACACAAATAGGCTGAAGTACTGTGCCCACAGATACACAGTATGGTTAACTTTACATA CATGGTGTATTATAGGTAGCTTCCACAAGCCTTTCAGCATCGCTTTTCATTTATCTATGT TGAAAGATGTAACTCTAACTCTCACATTCACTTTCTGAAGTATCAAAAACGCATTTGTTT TAAAGATACGAGCAGGGCATAGTTCTATCTAGTAGCACCTACTTTGTGCTACTTACAACT TTGCATGTAACTTTAAACCATAATATACAATAAAAGTAAGTACTAGAAAAAAAATACCTG TAATACTGATAAATGTAAGGAAAGATATACAATATCACTAGTAGTCAGGGAAATTCAAAA TAACAGTGAGACATATCACTCATCTAACTGATAAATTACAAAGTCTAACAATACCTACTA TTGGCAAGGGTAGAGAACAATGAAAACCTCATCAGTGACGGCAGGGACTTAAAGGAGCAG TACTTTTGGAGACAATAAGGCGATCTTTAGTAAAACTGAAGATACATATACCTTTTGATC CTACAATTTCATTCATACATAGGTACCCTAAGGAATCTCACATATATATACAAGGAGGAA CCATAAAATAACATTAATAGCAGTGTAATTTTTTAACTGCAAAAACTGGAAACAACTGTC CATCAACAGCAGAATTGATAAGTAAAGGATGGTGTACTCCTACGATAGAATATGACAAGC AATAGAAATGAATGGATTGAAGTACAAGCATTAAACATGGATAAATCTCAAAAATACTAC CACGAGTGGAAAAAAGCAAGTTGCAGAAGAATCAGAGCATCCTGTACTATCATTTATACA AAGTTCATAAACATAGTCTTTATTTCGTTTGATAGGAGACAATTGGCCAGGCGCGGTGGC TCACCCCTGTAATACCTGCACTTTGGGAGGCCGAGGCGGAAGGATCATTTGAGGTCAGGA GTTCGAGACCATCCTGGCCAACGTGGTGAAACCCAGCCTCTAATAAAAATAAAAAAAATT AGCCAGGCATGGTGGCGGGTTCCTGAAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGTA TCACTTGAACCCAGGAGACGGAGGTTGCAGTGAGCAGAGATCGTGCCACTGCACTCCAGC CTGGGTGCCAGAGCAAGACTCGGTCTCAAAAAACAAAAAAGAAAAAAAAAAAGAAAGGAG ACAATTATCTGAGGTGTAGGAAGAATTATGTACTTGGGAAGGAATAAATTGGGGCTTCAA TTATATTAGTAACATTTTATATCTTAAGCAGATGTTAGGTATATGGGTTGTTTGTTTGTT TGTTTGTTTGTTTTTGAGATGGAGTCTCACTCTGTCGCCAGGCTGGAGTGCGGTGGTGCC ATCTTGGCTCACTGCAACGTCCCTCTCCCGGGTTCAAGCAACTCTCCTGCCTCAGCCTCG TCAGCCTCGTGAGTAGCTGGGACTACAGGTACGCGCCACCAGGCCCGGCTAATTTTTGTA TTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCATGACCTCG GGTGAACCGCCTGGCTCGGCCTCCCAAAGTATATCATTCTTTATGCCTTTTAGTATGTCT GGAATATTTTATAACATACACAAGCAAGTCACATTAATTTGGCCTAGAAAGTCTCTCTGA ATCTTATAAGCATGTTTTGTGGTTAATGAGTTTAACAAATCTTTTCACAATTTCAATATT AGTTACTTCACTATTTCTTATTAAATCTGGCTTACAATGCTTCTCAGAAAATCGTATCCC AGAATCTACCACATAATAGCAGTTCAGCAAATACCTACAAAATTAAAATTTAAAATATAC TGAAGTATTCAATAAGGAGTAGCTCTTCAGAAAGAGACATATAGAAGCCTCTTGTATTTT AGAAGCAGTGTTGACAGGTTTGCTAAAGCTATGACCACGTCTCCCTCTTCTCACCCCCTA AAACAACAAAAAAGCCCTCCCATACACACGCATATGCACACACCTATACCTACACACACA CACACACACACACACACACACACACACACACTGGGAAGCGCTGGAATGCAGCCCAGTGTC CCTAAGAACCTAGAGTTGAACAGATTTAACTTAAAGATCAACTCTGCTTCTTAGCTGCAA CTGTCTGATATATAAATAAGAATTCCTTAAAAAGCTGTTCCATGTTAGCCGGGCGTGGTG GCACATGCCTGTAGTCCCAGCTACTCGGGAGACTGAGGCAGGGAGGTGGAGGTTGCAGTG AGCTGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAAAA ACAAACAAACAAAAAAACAAGTCGTTCCATTAATTTAAGAAATTAACATACATAAAACAC AATTCCTCACACACAGGATCTCAATAAGTAGTAGCTGCTTTTGTCATTATTATTCTATTT GGATTAAAATAGGTTTGGGTATAAAGACAGCCTATATAAGCAGCAGATAAAGATAAATTC CCAGATGTAATGAAGCGAAGGCTGGGCAGGCTGGCACTTGCATTCCTCATGAAACTGTTT TTCACAATTACAGGTTTGTTATTTTCACTTAATAAAAAGCTGCCCATATGCTGTACTTAA ATAGTTGAACTTTTCCATTTAAAACCCCAAAATTTGTGTTATATCTAATTTTGGACAACT ATTGTCATCTTTCTTTTATGTGCTTCAATTTATACTCAGTAACAAAACAATAGCTACTAT CAGAAGGACCATTATCTAATTTGCCTTAAGGACAGTGGGACATAGGCTTGTTTGCCTAGA GGAGCTGCCTCAGCTTAGAAGACTAACCTTACAGATAATAAAATCTGACATTTTTCCCAG AAAGTTTGGCCTAGTTTTTTAAAAAAGTGAATCTGATCAATTTTTAAAAGTATTCCTCAA ATGAAAAGGCAGAGAAGCCAATAAAAATAAACTTCAGGATAAATTAATTAAAAATATTCA AGGATATAAAAGATTTAAATAAATGAAATGATAGACAATGTCCTTAACTACAAAGGTTCA AAGTAGTAAAGAAATCAAGTCTCCCTAAATTGACCCATTGAATAAAATCCCAATCAAAAT AAAAAAGAGCTGTTTGGGAATCTTGACACAAACAATTCTAAAATCCATCTAGAAGAATCT GTGAGCTTTGTCAGCAAAGTCATAAAACAACAAAAAAGAAAAGAGACCAGTGACACCAAT TATTAAAACACATTATAAAGCAACTGTTACATAGGAAAAAGCTTGTTTGATTTTCATAAT TTTACAAAATCCAATAACAACTATTTTAAATGCAAAATCAAGCCACGGTAATATAAAATC GGATACTGGAGCAGAAATAGATGGACAAATCTGTGAAATCTAACAGAGAAGTCAGACTTA AGATTATAGAAAATTTAATATAAGATGAAAGTGGCATCTCAAATTAGTGGGGAAAAGATA GTTTCCTTAATAAATGGCATTGAGAAAACTAATAATGGATTTGGGGAAAAGTAACAATGG ATTCTTATCTCACTCCTTATACAAAATAACGTGTCTATGAAACAAATATTTAACTATAAA ATCATGAAGAGGCACCAGAAGAAAATAGGTACATATTTTTATAATCTTAAGATAGGAAAA GCTCTAAGCAAAGACAAAGCAGCAATCATCAAGGAAAAGACTGATAGTTGTAACAACATA AAAATGTAAAAAGAGACCAATATCCTAATAGAAACAAGGATAAAGGTAATTAACAGGCAA CTGGCTAAACTTAAGCCAATAATGTGAAAAGATCAGCTTTACTTCCAACTAAAGAACTGA AAGAGAAACAGTTATCAATTTTGCCATCAGACTGGTATAATAAGAAAAATTGAAAACTGG CCAACCAGTGTTGGCAAGGATATGGAGAAACAAATATTTTTTTATAAACAACTGGCAAGA ACATAAAATGAAACAGCCTATCTGGAGGTGAGTGGGTAATCTGTACCAAAATTTTAAATT TGTCTACCCTTTGATATGGCAATTTCTTTTCTAACAATTCACCCTGAGAAGAGAATCATA TCAATTATTTTATAAACCCATGGGTTCATAATGACACTTTTTTAAAAAGCTGGTCATTCT GGAGGCTAACAAGGCACTAATTTGTTTTTCTGAAAAGTGGCTTTCCAAGTGAGGGTTGGT AGAAATAAGAAGTCAAACATTTTACCCTTCCTTTCTTGTACAGACAGTATTTCAGCGTTA TCAAATAGCTGATGAAAAAAAGTTTCTTCTTTATAGAAGAATTACAGCTAAAAAGTACTA AAAGAATAAAATTTTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAG GCCGAGGCCCGCGGATCACAAGGTCAGGAGATTGAGACCATCCTGGCTAACACGGTGAAA CCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGCTA CTCAGGAGACTGAGGCAGGAGAATGGCGTGAACCTGGGAGGCAGAGCTTGCAGTGAGCAG AGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACGCCATCTCAAAAAAAAAA AAAAAAAAAAAAGAATAAAATTTTAAAATCCTAATTTACATACCTATCAGGATGGCTAAA ATAAAACACAGCAATAGCCCCAAATGTTGGTGAGGGTGGAGAAATTCACATACATTGCTG GTAGGAATGTAAAATGGTACTAGCCAGTCTGAAAAAGAATATGGCAATTTCTCACAAAAC TAAACATACCCATTATATAACCCAGTAATTGCATTCTTGGGCATTCATGCTAGAGAAACA AAAAGTTATGTTAACACAAAAACCTGTATATGAGTGTGCACAGCATATCCATGTGTAATG CCCCAAAACTGGGAAATAATCCAAATGCCCTTTAACATATGAATGGTCAGGCAAACTGCA GTATATCCATATCATGAAATACTAGTCAGTAATAAAAATAAATAAATTATTGATACAGGC AACAATCAGGGTGAATCTCAAGGGAATCAAGCTGAATGAAAAAAGGCAGTCTCAAAAGCT TGCATACTGTATAATTCCATTTTTATGTCATTCTTATGATGACAAAATTACAGAAATGAA GAATGCATTAGGGTGTTGCCAGGGGTTAGGGGAAGAGGGGGAAAGAGGTGTCATGTCTGT GGCTATTAAAGGGTAAAATGAGAGATCCTTGTGATGGAAATGTTCTGATTCTTGACTGTA GTGTTACCCATTTTTATCTACATGTGATATAACTGCACAGAACTAAATGCATACACACAC AGGCATACACATATATACACACACAAGTGTATATAAAACTAGTGAAATCTAAATGAGGTT CATTGCTTGTATCAATTTCAATTTCCCGGCTGTAAAATTGGACTATACTCAAGCAAGGTG TTGCCAATGGGGGAAAGTGGATGAAGGGAAATGGGATCTCTGTATTATTTCCTACATCTA CATGTGAATCTACAATTATCCCAAAATAAAAAAATTCCAAAAATTATCATTCTGAAAACT CTAATGAAATGAGTGTAGGTGATGATCATAAAGCGGTGTTAAAACCATCAGGTAAGACTG ACGGGGAACTTCAGCATGGGTACATCTGGGGCTGACAACACCTGAACTTCATAATCAACA TTAGTGAATGAATCGAGCCTCCAGATCTCATTCCCAGTTTATCAGCTATGACAGGGTATG GAAGAACATGTTAAATGACACCACAAGGAGGCCATCAGCCAAGTTCAGATGGTGGAAAAT TGTACTGGAAAAATGACTCGATTTCTTCAACAAATGGCATGAGAAATAAAGAAAAGAGAG GAAGGCTATATATTAAAAGAGACTTAAAAGAGCTAATCTCAACGGATGCAACATTTAGTC TTTGTATGGATCCTAATTTGTATAATATTAGATGATATTAGGAATTAATGTTAATTCTGT TTATATGATATTATGGTTGTGTTTTTAAGTCCTTATCTTAAAAGACTGAGGAATATACAG GTGAAATGATGACCTGTATTTGCTTTCAAATACCCTAGCAGAGGAAAAACAATTATAGAA GCGTAGATTAAAAAAAGAATAGTAGAGACCAAGCATGGTGGCCCACGCCTGTAATCCCAG CACTTAGGAGGCCGAGGCAGGAGGATCACTTAAGCGCAGGAGTTCAAGACCAGCCTGGGC AACATATCGAGACCTCATCTCTCCAAAAATAATTTTTTAATTAGCTGAGTGCAATGACCT CAGCTAATTAACCTTTTTATCTTGAAATAATTGTAGATTCACATGTAGATTTGGGAAATA ATACAGCGCTCCCATTTCCCTTCATCCACTTTCCCCCACTTGGCCACATCTTGCTTGAGT ATAGTCGATTTTACAGCCAGGAAATTGACATTGATACAAGCAATGGACATCTATAATCCT AGCTACTTGGGAGGCTGAGGCAGAAAGATCACTTGAGCCAGAAGTTTGAGGCTGCAGTGA GCTATGTACTGTGCTCCACACCACTACTCTCCAGCCTGGGAAACAGGACAAGGCTCTGTC TCAAAAAAAAAAAAAAAAAAAAAAAATACTAGACCATTGTTAACTGTTGAAGTTGGTTAT GTATGAAATCTCATATACTATTCCATTTGTAAATGCTTGACATTTTTCATAATAAAAACA TTTTGCAAGAAGACTATAAGTGCGCAAAGGTGTACATTCAAAGATTTTCTTTCACTGAAA TGTTTCTAACAGTTAACAAAATTAGAATCCACTTAAATGTCCAACAGTAAAGAAATGGTT AAGTAAATTATGCCACACAGTAAAACAAAATACCCTGCAGCCATTAAAGGGTGATATGGA TGTATGGATACCAACTTTGAAAGATGGCCATGACATACCAGTGAGTAAAAAAACAACTTA GGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGTCAAGGCGGGTGGA TCACCTGAGGTTAGGAGTTAGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACT AAAAGTACAAAATTAGCCAGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCGGGAGG CTGAGGAAGGAGATTCGCTTGAACCGGGGAGGCAGAGGTTGCAGTAAGCCAAGATTGTGC CACTGTACTCCAGCCTGGAAGACAAGAGTGGAACTCTGTCTTAAAAAAAAAAAGAAAAGA AGTTAAAGGGCTCGGTGCCGTGGCTCACACTTGTAATGCCAGCACTTTGGAAGCCCAAGG TGGGCAGGTTGTTTGAGTCCAGGAGTTCAACAGACCAGCCTGGGCAACATGGTGAAACCC CATCTCTACTAAAAATACAAAAGTTAGCCCGGCATGGTGGCGTAAGCCTGTAGTTGCGGG GCTGAGGTGGGAGGATCGCTTCAGCCTGGGAGGCAGAGGTTGCCAAGAGCCAAGATTGCA CCACTGCACTCCAGCCTGGGAGACAAAGCCAGACCCTGGTCTCAAAAAAACAAAACAAAA CAAAAATTAGAAAATTGCCTGTGTACAGTATCACTGCATGTTTGTAATGTAGGTGTGTTA CATGTGAACATAAGCATGGAGAGATGTCCAGAAAAGCCTTTACCAAAACATTAACAGTGG CTGTCTCTGAGGGGCAGAAATCCAAGAGACTGTTACTTGTTTTATATACTTTTTAATATT GTTTGATGTTTTACCAATCATGTGTTTTTAAATTAAGCTATTTCCAGTATACTTGTATTT TCACTTTTCTGATATATGTGTATGCATCAACAATAAGTTATTTTTAAAACTCAGCTATTT CCATTTGTTTTTAAGAAGGAAGAGACAACAGAACAAAGCAAACAATACCAAACTTACAGA GTACTGGAAAGGAGGGAAAGGCTAGGAACTTAGTTATACTCCTGCTATGTACCAAGGAAC ACCAAATAAATCCAAACAGCATTCGGAGGCACCAGAAGCAGGTCACACGCCCAGAGGAGT CTGAACTTGTCCCGCTGCCTCTTCAGTGGTATACGTCAACATCAAAATCTGCTTTTAACA TATCCCTCCAGCTACAATGACAGCTCACAGTTCCCCACACCCACCACGCTGTTGCCAAGC CTCTACCACACCTCTCCAGCCCCAGCTTCTCTCCAAAATCCCTCCGCCCCTCACCCTCTT TGCTTTCCCACAGAGGCTCCTTCAAGACCCAGCTCAGGGGGCTATCTTCTGCAGGACACC TTTGAGCTGGGCTCCTCCTCTCCCCCAGGCTGAGCCATGGGCCCCCTCTGTATGCTGTAG CACCTATCACTCGATGTCGATGTCATCTGTTTTAGAGGTCTGGCCCACAAGCTCTTTAAA GGGAAAGAATGCTGTATGGTCCGTTTTTGTAGACCCAACAGCTTGTGTAGCGTGAGGCAC CTCAGAAGCCCCATAAATGTTCTTTTTAAAATTGTTAATTTTGTGTAGAGCTAGGGTCTA TGTTGTCCAGGTGGGTATTGAACTCCTGGGCTCAAGCAATCCTCCTGCATTAGCTTCCCA AAGCACAGGATTACAGGTGTGAGCCACCACGCCCCGCCCACACCGCCCCCCGCCCCCCCA CCGTCCCGCGTAAGTGTTTGTAGAACTAATGAGCAGTTAAAGGGAGGAAAAAAAACCTGA TTTCTTCCATTTCCTAAGGACACACGAACATGGCAATCTTGCACTAGAGACACAGGACCC AAGAAAATGTTTGAGATGTGGAAAAAAAATCAAAATTAATATTAATTATATATTTATAAT ATGTAACAGTTCAACAGCAACTTGATTCTATTCATAATTATATATGTTAGATTTAATGTA GGATACGTGTATATTTCAACACATAAGACCCAGGTGGTGCTTTGAAAAGTAAGAGTGCCT AGGGCTTGGGAAGGTCTTTAAGCCTCCCTGCCTAAAAAACCTGTAGTTCTAGCTAGTAAC TTACCCAGCTAGTTTGGGGCAATGCAGAAAAGCCCATATGCAAAGCAAAACAAAGCTCTT ACAAACAAAGCAAACACAAAACTTCCATAGGAACTGCCTTGCATGGAAGTCCCAGTTCGA TGGCCAGTAACCACTGCATCAGAGCAGCCCAGCACCCTCCCCTCTGCAGCTGCTTTTTTG GTCCAAGCTGCAAGGATGGTGAGGAGGGAAGCATAGCTTGGAAGCTTTGAGACCCCATAG ATGAGATGGGCCTTCAGCCTTCAGTCCTGGAGCCTGTGGTGGAAATTCAGCAACCAGGCA AAGCCAGAACAAGCTAACTGCAACGCTCCTTAACTTGCCCAGTGGTTCCCCTTCCCAAGC TGGCTGGTCTCCCCAGGGCAGAGCTCTAAGCTGCAGAGTTATAAACCAGCAGGGGCAGGC TTCTGGATGAAAAACTAGGCACCACACATAAAAGCTCAGAGCCGAGCATCCAGATAAGCA CAAAACACCCACAAGATACTTGATTGTTGATGTTACACTGATCTCTGTCAGCTCAAAAAA AAACATCACTACAGTTGATTCTGGTTGTTGGTAGTAGTTATGGTTTATAAAGTTGGCTGT GAACACTGAATTAGCAAATCCTGAACCACTGCTCCTAGGGGAACTACAGGATTAGGGTCT CGTGAGCTCGACTTCACATTTTGGCAAATGATCAATACATAATCTTGTTTCATGCATGTT TCTGTTGAAAGAGACATTTATTATGTGTTGCTAATTCATCAGCATTGAACTCACAGCCAA CACCACTCACAGCCTGCCTGAACAAAGCTTATCTAACACAATATTTAATATTTTCTCCAT AAGGCACATCACAGCCTTCCTGCGCCTAGGAACACTTGACTGCACGTCTGCGCTATGCTT GGGGGACATTTTAAATAGCAGAATCACCAACAGAAAAGCATTAAAATGAAAAAAACATGG CAATAAATAGTCCACAAACTGGTCACTTGTTTACAATATAAGAGCTGAAACAAGAAGGCA GAGCGACTGGGCACGGTGGCTCACACCTGTAATACCAGCACTTTTGGAGGCCCAGGCGGG AGGATCACTTGAGCCCAGGAGTTTGAGATCAGCCTGGGCAACATAGCAAGACTCTGTCTC TACAAAAAAAAATACCAAAATTAGCTGGGTGTGGTAATGTGTGCCTGTAATCCCAGCTAC TCAGGAGGCTGAGGTAGGAGGATCCCCTGAGCCTGGGAGGCAGAGGTTGCAGTGAGCCAA GATTGCACCACTATACTCCAGCCCCAGCCTGGGCAACAGAGCGAGATCCTGTCTCAAAAA AAAAAAAGCATAGTGTTGTCTTGTTTGACTTCAGCTGGGAATGTATTGAGTGACTCAAAA TTTTCACTGCTCTGCACATGTCCAAGAATGACCAAGAAAGTGCCATGAATATTGCTTTTG GGGTTACAAATAAATGTTAGTATGTAGGTGAATTTGCAAATACAGAATCTGAAAATAATT AGGATTGACTGTACTACCTAAAAAACCTGGTATATATGCCTTATGGTATTCGAAGAAAGC ATCTTCTTGACTTTTTTGTAAGAGAATGGAATCCAAAATGAGCTATTAGAAGCTTTAAGG GTAGGAAAAGCACTCAGGCACTAAGGCAGTTAACATGGAGAAGACCCTATAACCACTTGC GCACTGACTGACCTTCCGTCATGCCACACGCAGGTTTCCAAGAAATTATGCTTATGACCA GAATTTTAACAAACTCCTAGAGAGAATCATTTTGAAAAACCAAAATATTTTATAAAGCAT ATATACTCCCTAAATTTAAGTACTGTAAAATTACACTTGTCATATATCAACTTTGCTTTA AAGTTTGTCTTATCCAAATGAAAAAGGTACAACTTTCAAAAAGGGAAGGTTCTAACCACT GTTCAATTAAATTTGGCCTAAAGCTGCCTCCACAGGTAATGAACTGCACCCTATCTTACT ATGTAAACAAGCTGCAACCTAACCTGCAAGTGTATTCTTGGAATAAGTAACTGAGTCTCA GCCAATCACAGCAGCCAAACTTTCAGCCAATACAGGCTGCAAACTGCCAAAACATGTCAA AATAAGGCAAAAGCCAAGCTGTAGCCAGTCAGACTATTTCAGTCTCTCACTTCTGTTTTC TGTCTATAAATACCACCTGCTGGGTATTTATAGACAGAAAATACTGTTGCTGGTTAGAGC TCTCTGAACCTTTACTGGTTCAGATGCTGCCTAATTCATGCATTGTTTCTTTACTCAAAT AAATGCTGCTAAATTGAATTTGTCAAAAGTTTTCCTTTTAACACCAGATTCTCTCTCTCA TTATAGACAGGTTATATATATAGAGAGAGTGTATTAGAGTGATTACATATACATACCTAC GTATGTATGTATATGTAATCATGCTAAATGCTTAATTCTCCTCAAGATTTAGGAACCAGT ATCACAGGGCAGAGAGTCCATCACCTTCCTTTTAAAACAAATAAATCAATAAAAAGAATA TATGAAATACAGTTGTTACTGTTCTTTTCTGTGAGGAAACTAAATTGGCAAAGGTGAGCA GATATAAAAGGAGAAAGAGCAGGAAATTGTTAAGAAGAAAATCACTGAATATGCAAATGA TTCTGAAACTGCCCTTAATGATTTTGGAGTAAATAATCCTTAAGTACAATTAAATAGCAT TCAAATATGTCATTTTATCAAAAAAAAAATGTTGTTTAAGGCCAGGGGTGATGTGGGGGA GCCTAAATTATTTTTATTATCCTTCTTAAAAAGATGGAACACCTAGCATACTGTTAGTAG ATGAATGATAAATGCTCACCATTTACAGAAAATTTAACCTTGGCAAATTAATAACTTTAT ATTAATTTCAGTTTAAGTTTAGAAGAATGACAAATTAAAATTAATTCACACTTAGGACTA TGACTAAAAGTAAAATGTTAATTGCATTTTAATCTACTCTGGCCTACTTCAAAAGCATAA TTTTAACTCTTGGATGGAGAACGAAATTTTCTTCTAAAAATAGATTTCGGTAACAATGAA ATATCAAGAGCTGGACATTATAATAAAAAGAAAAAAGGTAACAAGAATTTTCTTTTTTTT TTTTTTTTTTGAGAGTCTCGCTGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGAT GCGATCTCAGCTCACTGCAACCTCTGCCTCCCATGTTCAAGTGATTCTCCTGCGCAGCCT CCAGAGTAGCTGGGACTACGGGCACACGCTGCCACGCCTGGCTAATTTTTGTAGTTTTAG TAGAGATGGGGTTTCACCATGTTGAGCAGGCTAGTCTCGAACTCCTGATCTTAGGTGATC CGCCCGCCTCAACCTTCCAAAGTGCTGGGATTACAGCTGTGAGCCACCACGCCCAGCCCC AAGAATTTTCTTTTTAGGACAGACTGGAGAAAGGGTGGGAAAAGGATTGGGAGAGGCTGG TTGAAGGTACAGTTGAAATTAAATAGGAGGAATCAGTTCTGGCGTTCTATGGTTAACAGT ACATTACAAAATAGCTAGAAGAGAGATTTTTAAATATCCTCACCACAAAGAGATAAATGC ATGAGGCAATGGTCACACTAAATACCCTGATTTGCTCATTCTACAACTTATATATGTATT GAAACATCAAATTGTGCTCCCCAAATATGTACAATTACGTGTCAATTAAAGAATCTGCTT TAAATTTTTTCAAAAGCATATTTTTTTAAAATATGAAACTCAGCATTTATAAACTACATT AATGGCAGGGCACGGTAGCTCACGCTTGTAATCCCAGCACTTTGAGAGGCTGAGGAAGGC AGATCACTGACGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAA ACCCCGTCTCTACTAAAAATACAGAAAAATATTAGCCGGGCGTGGTGGCACGCTCCTGTA AGCCCAGCTACTGGGAGGTTGAGGCACGAGAATCGCCTGAACCAGGAGGTGGAGGTTGCA GTGAGACAGGATCGCACCACTGCACTCCAGCCTGGGAGACAGTGTGAGGCTCTGTCTCAA AATATAAAAATTTTTTTTAAAAAACCCTACATTTATAAACTAGGACTATATGAGGGTTAA ATAACATTTGAAAACTTCTTGGCATTTTTTTGTTGTTGTTTAGCTGCATAATACAAATGA AAGCACCATTATTCTAGAAGAGTTGGTTAAATCATCTTTCACTGACAGAACTTTTGAGAA AGATATTTTCAACATATTCATTTATAAATGATTTCAAAGTCTTCAACCTCAGCCATTTTT TAGATAGGTCAAAAAAATAAAATCTTCCACCTCTAGGGGTTTAGGTAACACAATAGGTAC AAGATAAATTTTAGCTAATCTGCTGACTGGCACATGCTTCTCCATGCTGTAACTGCTTTA CTGCATAATGACATTAGCAGCTGACCTTCCCTGAGGAAGAACCATAATCAGTTCCAAATA AATATATCCTTGATTACTGTTCACATCTAGAATACACCACCCACTGACAAATCAACATCT ACAATTCCTCAGACCTGCCATTATGACCTTGAATCTGGAGCAAATACACAAAACCATAAT TCGTTTTCTCTGCTCAAGATATGCAAGACTCTCCATAAACCATTCTGGACAGTTGAGTTT TCCCAAGGGTTGGAGACTTAACCATTTAGAAAGAATATTTCATACACTTTCTTAAACAAG GTATACTGGGTATAAATTCTATTTTTCTTGATTTGCAACCATCAGTGAGAATATTAATCC TTGTACTGTGTGTTGGGAGACATTTCTCCATGGGTCTCTCACACGTCTGCGTGTCTTAGA AGCAGAGGGGCTGGCTGCTTTCATTCTGAACTATCTTTCAAGGATATGTACATAGCGAAC AGCTTAGAAAGACAGAGACAGTATCTCCCACCAGACTGTCCAGTAGCATGAAGACATCTC ACTCCAGGGTAAGGCTGGGCAGGTTTGCTTGCAGCCCTTTATAAAGAATTTGATTTACCT AAACCTGGGGTTCTACAGCTGTGACATAAACCCACTGCACATGCAGTAGCAACTGAGCTA CTCTGATTGCCCCTGTGGGACCTATAGGGAGGAGGAATGGAATAAACTCCTCCTCTCAGT GGTGGCATTAGATTCTCATAGGAGCGTGAACCCTATTGTGAACTGAGCATATGAGGGATC TAGGTTGCATGCTCCTTATGAGAATCTAATGCCTGATGATCTCAGATGGGACAGTTTCAA CCCAAAACCATCCCCCTACCACCCCATCCATGAAAAAACTGTCTTCCATGAAACCGGTCC CTGGTGCCAAAAAGGTTGAGGACTGCTACTCTACAACACCATCCACCGAACAGGATGTAA TGGACATTTATAGAACACCCCACTAATGACTGCAAAATACACATACTTTTCAAGTATCCA CAACATAGATGCCAAGACGTCCACATCCTGCACCACAGGAAAAAACCATGACGAGTCTGA AGAAGTGAAATTAAACAATGTGTTCTCTGACCACAGTGGAATCAAATTAGAAATCAGAAA CAGGAACCTACCAGGAAAGTCTTCAAACACTTGGAAACTAAGCAACAGACTACTAAACAA GCCCTGGACCAAAGACGAAGTCTCAAAGGAAACAAAGGCCAGGTTCGGTGGCTCTCAGTT GTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACTTGAGGTCAGGAGTTCCAGA CCAGACTAGCCAACATGATGAAACCCCAACTCTACTAAAAATACAAAAATCAGCTGGGCT TGATGGCAGGCACTGTAATCCCAGCTTCTCAGGAGACTGAAGCAGGAGAATCGCTTGAAC CCAGGAGGGAGAGGTTGCAGTGAGCTGAGATCACTGTTCTCCAGCCTGGGTGACAGAGCG AGACTCTGTCTCAAAAAAAAAAAAAAAAGGAAACTAAAAATACACTGAACTGAATGAAAG TGGGACACAGTTAAAGCACTGTGAAGAGGAAAATGTATAGCACTGTGAAGAGGAAAATGT ATAGCACTGTGAAGAGGAAAATGTATAAATGCATAAATTAAATGAGAAAAAGTCTCAAGT CAATAATCTAAGCTCCCACCTCAAGAACCTAGAAAATCAAGAGCAAAACAAACCCAAAGC AAGCAGAAGGAAAGAAATAATAATGAGTGGAAATCAATACAATTGAAAACAGAAAAACAA TAGAAAATCCATGAAAAAAGAGGTGGTTTTTTGAAAAGATTTTTTAAACACTGATGAATC TTGAGCAAGACCAGCTAGGGAAAAAAAAAAGAAGGCACAAATAACCAATATTGGGAATGA AATGGAGGATATCATTACAGGCTCTGCAAATAGCGAAAGGATAATAAGGGAATACTATGA ACTAATTACATACATACATTTCACAGCACAGACAAAATGGACCAATTTCTTAAAAAACTA AAACTACCACCACTCACCAATATGAAATAAACAATATGAATAGCCCTATAACTATTAAGG AAATTAAATTCATAATTTAAGAACTCCCAAGAAAGAAATCTCTATAAGAACCTGATGAGG TGCCTGGAAAAAAGGAAGGAAGGAAGGAAGGAGAAAAGAAAAGAAATCTCCAGTCCTAGA AGGTTTCACTAGAGAACTCTACAAAACATTTAAAGAAGAATTAACATCAATTGTACACAA CCTCTTTCAGAAAATGGAAAAGGAACATTTCCTAATTCACTTTATGCAGCTAGTTTTTCC ACAATAAAGCCAGACAAAGCCATTACTAAAAAAAAGACAACAACAGACCAATATCCCTTA TGAATATAGACATGAAAATCCTTAGTAAGACATTAGCAAATAGAATTTAGCAATACATAA AAATAATTATACACCCTGACCAAGTGGTTTTTTCCAGAGAAGCAAGGTTAGTTTAATATT TGAAAAGCAATCAATGTAATCCACCAAATTAACAACCTAAAGAAAAATCACATGATCACA TCAAGTGATACAGAAAAGGCACCTGACAAACTTCAATGGAGACTCAACATCCACTGACAA TAAGGACTCTCAGAAAAACAAGAAAAGAGGGGAACATCTCAATTTGATAAAGAGCATCTA CAAAAAACAAACCAAAAAAAAAAAAAAACTAGAGCTAACGTTAGACTTCATAATGAAAGA CTGAATGCTTTCCCCCTAAGATCAGGAACAAGGAAAAATAGCCATTCTCACCATTCTTAT TCAACATGCTGCTGGAAGTTCTAGCCAGTGAAACAATGCAAGACAAGGAAATAAAAGGCA AAGAGATGAGAAAGGAAGAAATAAAACTGTCCCTATTTGCAGATAACATGATTATCTACA CAGAAAATCCCAAGAATTCTCAAAAAACAAAAAAATCTGGAATTAATGAATTTGGCAAAG TCACAGGATACAAAATAAACATACAAAACCAACTATATTTCCAAATAGTAGCAATGAACA CATGGAACACAATATACAATATAAATACAAATACAAAATACAATAACATTCACAATCACT CAAAAACAAGTATTTAGGTGTAAATCTAACAAAACATGCACAATAATATTGAAATTAGGC CAATTAATAACACTGCAATGGCCTCTAAGTTTTTAAGTGACAGGAGGAGTTGTTAGTCTC TCATTTTAAATCAAAAGTTAGAAATGATTAAGCTTAGTGAGGAAGGCATGTCAAAAGCCA AGATAGGTTGAATGCTAGGCCCCTTGCACCAAACAGCCAAGTTGTGAATACAAAGGAAAA GTTATTGAGGAAATTAAAATGCTATTACAGTGAACACACAAATGGTAAGAAGGCAAAACA GATGGCTCACGCCTGTAATCCCATCATTTTGGGAGGCCTAGGTGGGTGGATCACCTGAGG TCAGGAGTTCAAGACCAGCCTGACCAACATGGAGGAACCCCTGTCCCTACTAAAAATACA AAAATTAGCTGGGAGTCGTGGTGTGCATCTGTAATCCCAGCTACTCAGAAGGCTGAGGCA GGAGAATCACTTGAATCCGGGAGGTGCAGATTGCAGTGAGCCGAAACTGCACCACTGCAC TCCAGCCTGGGTGACAGAGGGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAGGCAAAA CAGCCTGTCGCTGATATGGAGAAAGTCTGAGTGCTCTGGATAGAAGGCCAGACCACCCAC AACATTTCCTTAAGCCAAAGCCTAATCCAGAGGAAGGCCCTAACACTCTTCAATTCTATG AAGGCTAAGAGAGGTGAGAAAGCTATATAAGAAGAGTGAAGCTAGCAGAGGTTGGTTCAT GATGTTTAAGGAAAGAAGCAGTCTCCATAACAAAAAAAGTGCAAAATGAAGCCTCAGGTG CTGATGTAGAAGCTGCACCAAGTTATCCTGAAGATCTAGCTAAGATTGATGAAGCTGGCT ACACTAAACAACAGATTTTCAACACAGACAAAACAGCCTTATATTGGAAGATGAAGCCAT CTAGGATCTGCATAGCTAGGGAGAAGTCAACGCCTGGTTTTAAAGCTTCAAAGGACAGGC TGACTGTGGGTAAGGGTTAAGGCAGCTGGTGACTTTCAGTTGAAGCCAACGCTCACTGAT CATTGTGAAAATCTTAGGGCCCTTAAGAATTATGTTAAATCTACTCTACCTGTGCTGTAT AAGCGGAACAACAAAGTCTGCATGACAGTGCATCTGTTTACAGCATCGTTTATTAAATAT TTTAAGCCCACTGTTGAGACCTAATCCTCAGGAAAAAAAAGATTCCTTTCAAAATATTAC TGCTCATTGACAATGCACCTGGCCACCCGAGTGCTCTCATGGACATGGACAAGGAGATTC ATGTTTTCATGCCTGCTACCACAATATGCATTCTGAAGCTTATGGATCAAGAAGCAATTT CAACTTTCATGTCTTATTATTTAAGAAAATACATCTTGTAAGACTACTGCTACCGTAGAT AGTGATTCCTCAGATGGATATGGGCAAAATAATACGAAAACCTTCTGGAAAGGATTCACC ATTCTAAAGGCCATTAAAAATATTCATGATTCAGGAGGAGATCAAAATAGCAACATTAAT AGGACTTTGGAAGGACTCCAACCTTCATGGATGACTTTGAGGAGTTCAAGACTTCAGTGG AGGAAGTAACAGCAAATGTGGTGGAAATAGCAAGACAACTAGAACTAGAAGTGAAGCCTT AAGATGGGACTGAACTGCTGCAATCTCATAATAAAATGCCAGCGGATTAGGAGTTACTTC TTATGAATGAGCAAAGAAAGCAGTTTCTTGAGACAGAATCTACTCCTGGTGAAAATGCTC TCCCTGTCGCCTAGGCTGGAGTGCTGTGTTGAAACGACAAAAAAAGCGTTTAGAATATTG CATAAACTTGTAAAGCAGCAGCATGGTTTGAGAGAATTGACTCCAATTTTGAAAGTTCTG CTATTGATAAAATGCTGTCAAACAGCATCTCATGTTACAGAGAAGTCTTTCTTGAAAGGA AGAGTCAATCAATACAACAAACATCATTGTTAGCTTATTTTAACAAATTGCTACAGCCAC CCCAACCTTCAGCAACCACCGCACCAATCAGTTAGCAGCCATCAACATTGAGGCAAGACC CTCGACCAGCAAAAGGATCATGACTCGTTGAAGTCAGGTGATAGTTAGCATTTTTTAGCA ATCAAGTATCTTTAATTCAGATATGTACATTTGAGGCCAGGCACGGTGGCTCATGCCTGT AATCCCAACACTTTGGGAGGCCGAGGCAGGTGATCACCTGAGGTCAGGAGTTTGACCAGC CTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATATAAAATTAGCCAGGTGTGGTGG CACATGCCTGCAATCCCAGCTATTCAGGAGGCTGGGGCAGGAGAATCGCTTGAACCTGGG AGGCAGAAGTTGCAGTGAGCTGAGACTGCACCATTGCACTCCAGCCTGGGCAACGAGAGC AAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGATATATACACCTGTTTGACATAA TGCTATTGCACACTTTATAACAGACTATACGTATAGTGTAAACATAACTTGTATATGCAC TGGAAAACCAAAAAACTGTGACTCATTTTGCTGTGATCATCATTTTATGTCAGTGGTCTG TGACCAAACCTGCAATATCTCTGAGGTATGCCTGTAGACAAGTGATTGGCAGCAGCTTAA TTCATAATAGCCAAAAAGTGGAAACAATAGCAATAGCCTTCAAAGAGTGAATGGTTAAAC TCTTTCATCTATATGATGGAATAGTACTCAGGGATAAAAAAGAACAAAACTATCATTCAC TCAACAAGCTAGATGAATCACCACAGAATTATTCTGAGTGAAGAAAAAACAATACAAAAA GGCTATATACCACAATTTCATGATATATAACATTATTGAAATGATAAAATTATAGAAATA GAGAAGAAAGTTGTGGTTGCCAGGGGCTAAGGAGGAGCTAGGTAGTGGTTGTGGCCACAA GGCAGTATTAGGAATCTTTGATGATGGAAATATTGTTACCTTACTTAAATGTATCAATGT CAATGTATTGATTGTGTTATGTATTCTATATGGTTTTGCAAGATGTTACCACTGGGAGAA ACTAGGTAAGATGTACAAGAGATCTCTCTAGGCTACAGTAGTCCTCACTTACAGTTCCAC TTTTGATGGTTTGAACCCAAAATGGGTTTCGTGGGTTTGTTACCCACGGCCAACCACTGT CCAAAAATATTAAATGAAAAATTCCAGAAGTAAACACTCACACTTTTATTACAATATATG GTGATAACTGTTCAATTTTATTATTATTTTGTTACTCTCTTACTGTGCCTAATTTAAAAC TCAAATTTTATTATAGATATGTATGTACAGTCAGCCCTCCATATCTGTGGGTTCTGCCTT TGCAGACTCAACCAACTTCAGGTGAAAATATCCTGGGAAGAAAACGATAAAAAAATACGG ATACACACACAAAAAAATTGTAAAATACAGTATCACAACTATTTATATAGCATTTACATT GTATCTAGTATTATAAGTAACCTAGAGATTATTTAAAGTATACAGAAGAATGTGCATAAG TTACATGCAAATACATCATTTTATATAAGGGACTTGAGCATCCATGGATTTTTGGCATCC ATAGGAGGTCATGGAACCAATCCCCCACAGATATTGACAGACAACCATGTAGGAAAAAAC ATATATAGGGTTCAGGCCTCCATTGGGGGGGTCTTGGAATTTAGCCTCTGAGGATAAGGA GGGACTACTATATTTTTTATAACCGCACGTCAATCTATATAGTTAGCTCAAAATAGTGTT TTTTTGAACAACATTGCCCTTTGAAGGAATTATTAGCCAAAGCATGTCAGCAGATCTTTT TTTCTTTGAGGCAGGGTCTCTCCCTGTTGCCTAGGCTGGAGTGTAGTGGCAGGATTATAC CTCACTGCAGCCTTGTCACCAGATTTTAATACAGTGGCGTTTTGAACAATAGGAGTCCAA CTTCTATTTTTTTCCACCTCTGCCATCCCTGAGAAAGACCAACCCTTCCTCTTCCTCCTC AGCCTACTCAGTGTGAAGATGACAAGTCTGAAGACCTTTATGATCTACTTCCACTTACTG AACAGTAAATAATTTTCTCTTCCTTGTGATTCTAGTAACATTCTTTTCTAGTTTACTTTT AAAAATACAGTAAATAATACATATAACATATAAAATGTGTTAATCAACTGTTTGTTATCA GTAAGACTTCGAATCAACAGTAGGCTATTAATAGTTAAGTTTTAGGGTAGTCAAAAGTTA CACACAGATTTTTGACTGTGTGGAAGGTCAGTGCCCCTAACCCCTGTGTTGTTCAAGGGT CAGCTGTATTTCTAATTTTCTTGTTGACAGGCAGAAGAGTTTACTAAGAAAATTCACCTC TAACAATCTAGTTTCAAGGCATTTTCCAGGTGGTTTGTCATGTGCAGCTAGGAGCTAAAT AGGCAAAGATGTAGAAGACAATGTAGATTTAGAAGAGAATATATAACACATTTTTATTAA AGTATGAAGTTGAACAAGAACTCAGTACTGAACTCAAGATATTTTCATTATTCCTGCCCA TAATCATGAATGCTTCTAAACAGAGCGCAGGCAGCACCTGACCAGTGTATGACCAACTCA TGGAGAAGCAATTCTAAAGGAAGTCCTGTCTTCCTTACTTCCAGCCAGCCTAGGATACTT CCCTATCAGAATCTTCCACTCCCAAGCCATCTCTGCAGCTCACCTCAGCCCTAACCACCC CCAGCCCAAGTTGGCTAGGCAAAAAGAAGAGGAAGAAGAAAATGGTAAACATGTGCATGC CACACCTGTTTACTCTTCTCTCCTGCCCGCCTTGCCACAATTCCTCTGAAGACGAACACC CAAAGGAAGGAGAGGGTAGGAATGGCACAGGACTTGCTAACACCTCCAGCTGCCAGGCCT CCTCTCACCAGTTATGAGGAAAGCCAGGCTTCATTCTTACCCCACCCCCACCAACTCTCA CCTCCCTCAGCCTTCACAAAAAAACTCCACCCATACCTCCCCAATCCTATCCAGAAGCAT TTCCAAAGTCCCTTCTTCCCTTTAAAACTAGTCTCCTGGGCCAGGCGACATGGCTCACGC CTGTAATCTCAGCACTTTGGGAGGCCGAGACGGGCGGATCACGAGGTCAGGAGATCGAGA CCAACCTGGCTAACACAGTGAAACCCCGTCTCTACCCAAAATACAAAAAATTAGCCGGGC GTGGTGGCGGGCACCCATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGA ACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCACCACTACACTCCAGCCTGGGCGA CAGAGCAAGACTCTGTCTCAAAAAAAAAAAAGGCAAAAAAAAAAAACTAGTCTCCTCCAG CTCTGCTGAAGCCCTGCCACAGGAGTCACATTCCAAGTAACCGGAAAGAAAATACAGAAT GAATGTAATCCATCATTTGTGGATACCCTAACCCTCGCCTTATAGTAACTCTAGTTACTA GAGCAACTAGGAAGCTCTCCTGAAATCGTAGTTCATTTTCTGGTGATTAGGTTACTTTCA GAAATTAGAGGTTTCATTTATACTAAGAAACTTAATATGAAACTACTATTCCCACCTAAT GAGCAAGAAATGCTTTCACTTATTAATATATCTTGCCAGGGCGAGGCACAGTGGCTTAGG CCTGTAATCCCAGCATCCTGGGAGGTCGAGGCAGAGGGATCACTTGAGCTCAGGAGTTCA AGACCAACCCAGGCAACATGGCAAAAACCCATCTCTACAAAAAATTAGCCAGGCATGGTG GCACACACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTGGGAGAATCATCTGAGCCCAG GAAGTCAAGGCTGCAGTGAGCCATGATTGTGCCACTGCACTCCAGCCTGGGTAATGGAGT GAGACCCTGTCTCAAAAAAATAGAGAGAGAGAGAGAGACAGACAGACAGACAGACAGACA GAGATAGGAGAAAGGGGGAGGGAGAGAGAGGTAGGGCAGAGAGAGAGGGAGAGGAGAGAG GAGAGAGAAGAGAGAAAGAGAGAGAGATCTTGCCCATCTGGCTTTATTCTGAGACCCACC GAGTGAAGCCTGTGGCAGACAAGAGTGGTTTCTATGAAAAAAATATAAATAAATAATAAA TAAAAAGTGGTATTCCCAGATGTGAAGGCAAACTACAACAATGACAATGGCCTCTCTATT GATTGGCAGGGTCAATTTGGCTGACAAGTTGGCTGGTCAGGTTTCTCATCTCCAGGTGCT CTGCTTCCAAAGCTGGGAGTGGTACAAAGAGATTACATGGTCCTTGCACCAGAGTTCATC TACTTTACTCAACCCCATAGTTTTACATTCAGTTCTAACAAATTTAGATGGTTTCCAAGT TCAGTTAATCAGACAGAATAAATCTTCATAGAGAGAAAAACACTTTATTCATTCAACAAC TATTTGTTGAGTGCCTAAGAAGTGCCAGACACTTGGAGATTCAGCAGTGACTGATACACA ATGACCCCATCTCCTCCTGGCTTATGTGTGTTTGGTGGGAGGCAGAGGCAGAGGGTTAGA CAGTAGAAAAGTAAATTAAAATTAAAATAATTGTAAATAAAATAATTACAACATGTTACG GTGGCTAACAAGGACATAAACAGAGCTGAGGATCTTGCATTCTCAGAATTATGAAAAGCA ATATTCAATCAAGGCCAGGCGCAGTGGCTCACACCTGTACTCCCACCACGTTAGGAGGCC AAAGTGGGAGAATCCCTTGAGCCCAGGAGATCAAGACCAACAACATAGCAAGACCCCATC TCTACAAAAAATAAAAATAAAAATAAAAAAATTAGCCAGGCATGGTGGTTGTGCCCACAT TTCCAGCTACTCGGGAGGCTAAGGTGGGAGGATCGCTTGAGGCCTGGAGTTCAAGGCTGC AGAGAGCTGAGATTGTGCCACTGAACTACAGCCTAGGTAAAAGAGTGAGACCACATCACA CGCGAAAATAATTAAAAAACAAAAACTAAAAAACTAAAAGCAACTGATCTTTGAGAAGTG ATAACTGCATTCTCAAAGTACCTAATCTCAACAATACCCTAACTTAAAACCTGCTGACTA GGAGATGTATTTGACTGCAAATCTGGCCCACACAAGCAATAATCTGAGTTTCCATCAAGG AAGCTGTAAGCACCAAGTAGAGCAAAAACAAATCCAGGCCTCAAATGGAAAAAGCAGCTC TGAATTGTGATTTTCGAAGAAACCTGCATTTCTTACACTTCAGTGTACTTTCCCCATATT TAACTCCAAGATTTTTGTTAATTTGTTTGGTTTTCCTTTCTCAAACAAAATTATGCTCAG ACTGAAAACCCTAGATTTGTTCCCTATTGCATCTTCATTTCTTCCCAAACATTCCATAAA ACGTGACCTACATTAAGTTAGCAAGTTAAGTCTGAAAGCGTCTACCTTCCCTGGGGAGGG GGAAGGTGTAGGCAGGGCAGAGATTTGTAGTCCAGCCCTCTTGCCACAAATTATGAATTA GAGAGGAATGACTTTGCTTTTTTAATGATCTCCAGAGAATTTTCCATCATTTCCCTCTCT TCACCCAGCTCCTTTGCAACCACTGCCAGAGAAGTCTTCCTTTAGCTTCTTAAACATCGA TCCTAAAACACTTCCAGACACCTGTGCTGCTCCTTTCAGTTCCCATGGAGATTAGGCTGT GTAACAATCTCGCAAAGACGTTCCCCTCCGTCTCCTCATCCTCTTTTCAAACCCTTTTAC GATTTCCCATCTCACTCAGCATGACAGTCAAAGTCCCTGTGATGGCCAACTTCTGCATCA CCTAGCCAGTCTGCCACCGCCAAAACTCTCCAGCCTCATCTTTCTACTCTTCCCCTGGTT CCTTGCCCACGCCTTTACACTTGTTCTCTGCTTGGAATCTTCCCTCCCCTCCTTGAGGAA CTTTCTCAAATGTCACCTTCCCTCAATACTCCCCCTCCTCCATTTAAAACTATAAACTTC CAACTCTCTAAGCCCCTAAAGTACTCTATATTTAACTTATTGTATAAACTACTGTCCCTA CTTGTAAGTTCCAAGATTGCAGGGATTCACCCGCTTTGTTCACTGCTGTCTGCCAAGGTC TAGAACAGTGCAAGTTACCCAACAGGAGTTCAATAAACAGCCATTCATTTAACAAATATT TGCTGAGCACTTCGTCCCGTCCAAGTTTGTTAAATCAAGACAAATAAGACACCGTCCCTG CCTTTAACGCACCAGATGGAGAAATGCACCACAGACATAAATGTGCAATACAGGCCTGAC ACTACGGCCACAAGCAAGTCAAAGAACGTGCCAAAAGTTCAGAGGAAGAAGCCTCGGCTT CGCCTTTCGGGAGACCAGTCCAGCTTTCCACCATCACGCTGCTCATCAGGGACCATCTCC GGGGGTCTCCTCTAGACCCCAAGGGAGGAGCGGGTCCCGCCCGCCATTCCCAGGTCTCAG AGTTTACTTGTCCAGAGATGCAACTTCCGGCCTCTTCAGGCCGGGCAAGATTTAAGGAAA GAAAAGAAACATAAGGACCTCCGTTCTTCGGTCTCCGTCCCCTCCCCTTCCCCCGCGTGC CGTCCCCACAACGGGCCAGGACTGAACCCAACTCTCGACCAACTCCCGGCAGCAAAACTA AGCACCCTACTTCCGTTGTCCCCACCTGTTCCCGGCGTCCCCTTCGGCTACTCCCGGCGT TTGCGCAAGCGGTCCCACGTGGGC bcftools-1.21/test/csq/ENST00000409523/ENST00000409523.fa.fai000066400000000000000000000000211467060157400215260ustar00rootroot000000000000002 64644 25 60 61 bcftools-1.21/test/csq/ENST00000409523/ENST00000409523.gff000066400000000000000000000046661467060157400211670ustar00rootroot000000000000002 ensembl_havana gene 21 64624 . - . ID=gene:ENSG00000186132;Name=C2orf76;biotype=protein_coding;description=chromosome 2 open reading frame 76 [Source:HGNC Symbol%3BAcc:27017];gene_id=ENSG00000186132;logic_name=ensembl_havana_gene;version=10 2 ensembl_havana transcript 240 64478 . - . ID=transcript:ENST00000409523;Parent=gene:ENSG00000186132;Name=C2orf76-004;biotype=protein_coding;ccdsid=CCDS42739.1;havana_transcript=OTTHUMT00000330585;havana_version=1;tag=basic;transcript_id=ENST00000409523;version=1 2 ensembl_havana three_prime_UTR 240 267 . - . Parent=transcript:ENST00000409523 2 ensembl_havana exon 240 344 . - . Parent=transcript:ENST00000409523;Name=ENSE00001581014;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001581014;rank=6;version=1 2 ensembl_havana CDS 268 344 . - 2 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 2 ensembl_havana exon 9418 9499 . - . Parent=transcript:ENST00000409523;Name=ENSE00001335430;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001335430;rank=5;version=1 2 ensembl_havana CDS 9418 9499 . - 0 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 2 ensembl_havana exon 15262 15299 . - . Parent=transcript:ENST00000409523;Name=ENSE00001335434;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001335434;rank=4;version=1 2 ensembl_havana CDS 15262 15299 . - 2 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 2 ensembl_havana exon 18950 19000 . - . Parent=transcript:ENST00000409523;Name=ENSE00001335435;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001335435;rank=3;version=1 2 ensembl_havana CDS 18950 19000 . - 2 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 2 ensembl_havana CDS 37623 37755 . - 0 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 2 ensembl_havana exon 37623 37767 . - . Parent=transcript:ENST00000409523;Name=ENSE00003687102;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003687102;rank=2;version=1 2 ensembl_havana five_prime_UTR 37756 37767 . - . Parent=transcript:ENST00000409523 2 ensembl_havana exon 64153 64478 . - . Parent=transcript:ENST00000409523;Name=ENSE00001584682;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001584682;rank=1;version=1 2 ensembl_havana five_prime_UTR 64153 64478 . - . Parent=transcript:ENST00000409523 bcftools-1.21/test/csq/ENST00000409523/ascii-art.txt000066400000000000000000000015141467060157400212650ustar00rootroot00000000000000 18990 19000 37744 37755 37767 eeeeeeeeeeeiiiiiiiiii ... ..eeeeeeeeeeeeeeu....uuuuu GTGGCAGGTTGGTCCTTAAAGGGATATCTACAAGAGA ... TCCAGGAGCCAT GTGGCAGGTTGGTCCTT----------------GAGA C CDS 268 344 .. 77 CDS 9418 9499 82 .. 159 CDS 15262 15299 38 .. 197 CDS 18950 19000 51 .. 248 CDS 37623 37755 133 .. 381 GTGGCAGGTTGGTCCTTAAAGGGATATCTACAAGAGAAAGATTATTTTTTTACACAA GTGGCAGGTTGGTCCTT----------------GAGAAAGATTATTTTTTTACACAA GTGGCAGGTTGGTCCTTGAGAAAGATTATTTTTTTACACAA---------------- 1234567890 eeeeeeeeeeeiiiiiiiiii ... ..eeeeeeeeeeeeeeu....uuuuu 12345678 xx: CTACAAGA GAGAAAGA a1: (null) aoff=11 a2: (null) a3: GAGAAAGA bcftools-1.21/test/csq/ENST00000409523/long-overlapping-del.txt000066400000000000000000000005161467060157400234370ustar00rootroot0000000000000018990 TAAAGGGATATCTACAA T frameshift&splice_acceptor|C2orf76|ENST00000409523|protein_coding 18990 TAAAGGGATATCTACAA T frameshift&splice_acceptor|C2orf76|ENST00000409523|protein_coding 37744 T C synonymous|C2orf76|ENST00000409523|protein_coding|-|4G|37744T>C 37744 T C synonymous|C2orf76|ENST00000409523|protein_coding|-|4G|37744T>C bcftools-1.21/test/csq/ENST00000409523/long-overlapping-del.vcf000066400000000000000000000011061467060157400233720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 18990 . TAAAGGGATATCTACAA T . . EXP=frameshift&splice_acceptor|C2orf76|ENST00000409523|protein_coding;type=ENST00000409523:120078770-TAAAGGGATATCTACAA-T 2 37744 . T C . . EXP=synonymous|C2orf76|ENST00000409523|protein_coding|-|4G|37744T>C;type=ENST00000409523:120097524-T-C bcftools-1.21/test/csq/ENST00000410009/000077500000000000000000000000001467060157400166365ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000410009/ENST00000410009.fa000066400000000000000000000132041467060157400207550ustar00rootroot00000000000000>2 2:71057327-71062972 AAAAGTGCACTTGGAGTGAGTCCTTGACCCAGGCAGCATTTTATTCTGAGGAAGCTGGAA GGTGAATTCATGAAGGCACTGAAGGCTGCTTCCCATGCACAAGACACAGGAAGATAGGAA ATGCAGAAGGAGGAGGAGGTGCCGGAGAGGTGAGGACAGGGGCTGGATGGACGCTGGGTG GAAGGCAGGGCTCGGCACTCCAGTGTACTAAGGGAGTGGAAGGAGAAGGGAGGCTGGGTG CCAGCCGAGCTCTGAAGGAGATACAAGTCCGTGTCAGCCACTGACTTGAACCAGAGAAGA ACGGGTTCAGGCTTTAGATGATGTGGATGAAGAAACCACTGGGGACATACCATGAGCAGG ATTTCCAAGAACAGAGCTATTTGCACTGCAAACACAGCCAGCTGCTAGCTGCCAGCACAG CTAAGCAGAGACATGGAAATTCTAGGGGGTTTGGCCAAGAAAAGCCCTGGATGACAATAT CAGGAGAATTGCTTGGTTGCTCTGGAGTAACTTTGATGTGATGAAGCTGAGGTTTCTCTG AAAGAGTGGAAAACCCCAGGGTGTTATGCCGGATTACGGGTCTTGATCCTCCTTAGCAGG GCAATTGGAACTTCTAAATCCTCTCTACCCACCCCTCCCACTTTAACCTGAATTCTCCTT TCCATTCCAGCTGCCTCCAAGACGTCAGAGAATTTCCAGCCAAGACAGACGGACTCCAGA ATGCCACTGTGGGACAATTTTGAAGCAAGAAAAATTAACGTGCAAAGTCATCCTGGAGTC TGGGGAAGAAAGAGGCATTTCCTCATGTTTAACAAGCGTTGGAGCTCAAAGAGTGAGCTT GGGAGCCTGTCCTGTCACGGTTCTGATGGGACATAGGGTCGCTTACAAATGAAAAGAAAC GTTTTGTCACATGGGGCATCATTCCAGGCCTGAAGTGAGGGAGCCTTTATATTGCCACAG TGTTCATTGTTCCCAGCATTGTTGGGCTCACCTGGAATCCAGAACCTACCAAGAGCGGGG AAAAAGATGGATTTACAAAGTGGAAAATCAAAAAGAACTTATTTCCAGTGAAGAAATGAG TTAACTCAACCCAAGCTTTTGTCCTAGGGAATGGCATAGCAAATGTCTGCACCCAAGCCT CAGAGGAAGGGGACTGGTGAGACTTCGACCTCTAAGCTTTCACATGCCCCAAGTCCAGGC CAAACCAACCCACCACTTTCAAGTCCCTACACAAACCCACACTGTGAAGACCTAGACTCA TGACAAGATCCCTGAAGCTGGCCAGGTAGAAGGCCTTGTTGCCAAACCCCAGAGGGCGTG GAGGGCTCAGGTCCACAGCCAGTTGGTGACAGGGTTGTGCTCGATCTTGGTTGCAATGTT CCTGTCACTCTAAGACAGGGAAGAATCAGAAACCCTGTCTCATGGGGAACATCGCCCCCA CTCCCTTCATGCCCTGGCCATGGCCGGGGAAAGTCAGGCTGGCACGGAGGGCTCCAGGGG CTTACCTCACACTTTGGACCTTGTTGAATGGCGTGTCATCCACCCAGGACCAGTCCCCTT CCATCCCTGCTTTAGTCAGGCCAATCCAGTAGATGAGTCCCCCCGCTGTTTTATACAGAA ACTCCTGTAGGAAAGACAGGATAAGCAGAGGTGCGGCCACACTTGGAGCTTGATCATCTG TCTCTGGGTGTTCTTCACCTGCGCTCAGTGACAGCCCTGACCCACAGATGCGCTGCACAA ACTGGCCTCTCAAGCTTCTTCCTGCCCTTGCCCAGAGCCCAGATTTCATCTTCCAGATTA TGATGTGTCCCTGCTCTGCAGCTAACAAGCTCAGGACTCAAGCCTTTCTGCCACTCAGGA AGCAGGTGCTGAAGCACAGGAAGGCCTCAGCTGAACTCCAGAGCACGGACCGCAAGAGAA TGGTTCATATGATAATACCTGAATTAAATGAGCCCTGAATCCACATACGGCACTGTGCTG AGTCGTCCATATGCATTCTCTCCTTTCCTCTGAGGCAGGTGCCATCACCATGCATGTTTC ATCAAGTGAGGGCCAGTGAAGTTTGCCCAGTGAAGTTGGGTATTCCACCCAAGCTGCTAG GACTAGTTAGATGGCAAGGTTCAGGCTCTAGAACTACGCCAGAGCCCAGGCTCTGACCTG CTCTGCTATCCCACCTCCCAGATGAAAAGGGCCTGCCCAATTTCTGCCTCACCAGGCAGG AGACTTCTTGAGTCATGTGGAATCATTAAGGCTGTTCACAAATATTTCTTTTTTTCTGGG CACATGGAAAGTAGATCCTCTCTGCCCTGTTCCAGGAGTACTGGAATCCAGGATCCTCCC AATCCAGGAGTACTGCATAACTTACTTAACTTAATTAACATAACTTAAGCTAGTGAAATG TAAGCAAAAATGAGGTATGTTAAATCTGGGCAGAAGCTTTGCACAATATGTCAAGTTCCC CTTTCCTGCCCCAGCAATTGTGGAGACATATTAAGATGAAGACTCCTTGGGCCTGGGTCC TTGAGTAGCCACAGTGAGCACAGCCCCCTTGCCGGCCCTTATTCGACATGCTACTGAGAA CCAATCCTTCTTCATTAGGTCATCAATATTTGGGGATTTTTGTTCACGCAGTATAATCTT GCCCATCCTCCCTGGCCCAGTGCTCATACGCCCCCTTCACAGAGCCCATAGGCACAGCAC TCACCTGCTCACTCTCTGAGGTCACCGAGGTCAGGTGTGAATTCCTGGACACACAGAACT GCTCGGCACTATACCAGGTCTTTGGAATGAGAGAAAAGTAATAGAAGTTCCCCTTGAAGT ACTTCCAGCCTTGAGAAACCACCTGTAGAATATCATCTAGAGAACAAGAGGTAAAAGTGA ACGCTGGTATTCTTGATTTCTTGGGATGCTGGCTTGGTGGGGGCACTTGAATGAGGTCTC AGAGACAGCAGCAAATGGAGCTGTGCGCTGGTGTCCTTGGGTCCTTGTATAGGAGATTAG GGACACTCTTTCAAATCCTGAAAGTCAGACAGAGACTAATAGAGTCTCTGGGACTGGAGA GGTTATAATGCAAGAGGTTGGACAAAGAGTGTCTTCCCCATGATGAGGAAGCAACCCTCC ATCGGCCATGACAAGTGGCTGAGCCCCTGGACTCTAGAAAGGAACTTGATGGGAAATGAC TAGGTGTGGGCCAGGGTGGACATCCCCTAATGCTTTTACATTCTGCACTTTTGTGTGGGA GCTCTAGCTGGACCCTGGTCTCTTTTCTCCTAACAGCCCCTAAGTCCTCCCCAACCTCAA GCCCTCTCTCCTTAACTTCCTAGCCCATGGCTGCCCCTCTTTTGCCCCCACTCTCCTCCC CAACCCACCAGCCCAATGGCCTCAGGTCTGGGACAGGTAAGATCCCATGGGCCACTGGTC AGCTTCAATGTAATTTTCTGAGTCACTTACTTTGTCGTTTGAGCAACTTGCTCATATTCT CCAAGCTGCCCTGGAGTGCCCGGATCTTTGTATTTAAAGCACTGGCTTTCTCCAAATCAC TTTTTAACTCTGGGATTTGGGCATTTAAGGTACTGACTTCTTCCCAACTTCTTGTTAAGA TCTGGATCTGTGCGTTGGCCTTCTCCACACTGGTTTTTAACTTCAGGAACTGAGAACGCA CATAACCCAGGCTCTCATTCACCATCTGGATCTGAACGCCAGCTGCCTCCATGCCGTCAC TATTCTTTTTAATTTCAGAATCCAGGGTGCTGATGTTGTCCACACGACCTTTCAGCAACT GGACATTGGTCTTTACATCTGATATGGTGCCCATAAACCGGGGATCTGGGATTGAGAAAG TCAGGAGGTCAGCTGAGGGGAGTCCCAGGGACAGGAGTGGGGGTGTTGTCAGGTTGATCA AAGGAAGGGAAGGAATAGGCTGAAGCTTCCCAAAGAACCAAGACAGTCCAATGGGCCACC CCAACCCTCCAATCATTCATTAACGTACAACAAACGTGCAATGGGCACCTACCATGTGCC AGGAACACAGGTGGATACAGATAATGGGGAGATTGATAAAACACAGGCTCTCTGTGAAAA GATTTCACAGGCAAGCAGAAGCAGGAGTTAGAAACCATTCCTGAATTTTCTGAGTGTTCA GGGAACATTTGATAAAGGGTGCCCTCCATGAGCCCCACCACTGTCCCCAGAACTTGATTC CCCCTAGACCCCACCCCTTGGTTGCCATCCCTCTGTTTTCAGAAACCCCTGCAGTGGCCA TCTGCTAGGACAGCACCACTCCCCCACATCTGTCCATGGGCCCCTCTGTGACCATGGGAA GAACCAGCCACTAATCTGGAAGTGGCTTCTCCAGAGAACATGGAAGAGGAGATTACAAAA CTGTTTCTCCCCTTCCCTTGCCCCACCCACTTTCACATTCTGCTCAGGTCCCAGGCCTGG GTACCAGAGAGAGGATCAAAGATAAACCAAGAGGCTCAAAGGCGAGCCCTGAGGAAAATG CGATGTTAGAGGCCAGGGGTCTAGGATGGGGCAAGGGGGACTCTGCTCAGAGCCTACAAG TCTAAGCCCAAATATGTCCCGAGGCCACAGAGGGAGAAAAAAAAACCCAACAGCTTCTTG GGTCCCTTTGCTCTGCTTCCTGGAGCCCTGGCAGGAGGAAGAAGGCTCTGCCAGCAGCAA AGGCCATGAAGCCTGACAGAGCCAGAAAAGGAAGAAAGATAAACCATGCAACATCAAATG AGCAGGAAGCCTCCCTAGATGTGATCTTCACAGGGACAGGAGAATGAAGACAGCACCAAC GAGTCCTGGGGAGAGGGGACTGAGTCATGGAGATCTGTTGGCTCGTTGGCCAGGCTCTCC ATCTGGTGAGCTGGGGCCAATGATACATGAGGCTCGGTCCTTCACAGGGTCAGGAGACAT TGCACTGTCAAGGACTGTCCACAAGGCTCTAGATCCAAGGAGCAGAGCTCAGATTGGTGG GGGGTGGACGGGGAGAAAATAGCACAGGATGTAAAACTAGATCAATGTTTCCTGAGGACA AAAGAATGTATCCTTGAGCACCAATGTGCAAATGCTAATCCCAATAATCTCCCAGAAATT GGGAGGGAAAGAGCATCAGCTCACCGTACTGGGGGCAGCACAGCCTGTTACTGCACATGG AAAGAGGAGGAAGGAGACAAATGAAAAAGCCACAGGCAGGAGAAACCCGGAGAGCAGGGA AGTGGTCTCGATCTGAAGGGAGCCGGCTGGCCACAGAGAGGGGCTAAGCCCAGACGATGA AACATGAGGACTTACAAAGGACGGCCTGCAGCAGGACGGAGGCGACCAGGACCAGCGTCA GGCAGATTAATGCAGCACGGACTGTGGGTGTTTTCCCCGGGACCAGAGATGGACCGGACT TGGGAGGAGGCTCTGTTGGAAGAAGAAGAAAATGTGTGTTGAAGGAGCAGCAAAGGGCAG GTTTGCACACAGAACACGGAGCAGGTTCTCAGCAGCGATGTGGCTTGCTCGGGGCCAGAG GGAGATGTTCTGTTTGTCCACAGTGAAGTGCGCATCAGGGGCCTCCTTCTCCACAGTCAT CCTGAGTGCTCACCCTTATCCTGGGAGCACAGGTGCTTCTGGCTGCCTGTCTCTCCAAGG GCTCTT bcftools-1.21/test/csq/ENST00000410009/ENST00000410009.fa.fai000066400000000000000000000000201467060157400215030ustar00rootroot000000000000002 5646 23 60 61 bcftools-1.21/test/csq/ENST00000410009/ENST00000410009.gff000066400000000000000000000046461467060157400211430ustar00rootroot000000000000002 ensembl_havana gene 21 5626 . - . ID=gene:ENSG00000116031;Name=CD207;biotype=protein_coding;description=CD207 molecule%2C langerin [Source:HGNC Symbol%3BAcc:17935];gene_id=ENSG00000116031;logic_name=ensembl_havana_gene;version=7 2 ensembl_havana transcript 21 5626 . - . ID=transcript:ENST00000410009;Parent=gene:ENSG00000116031;Name=CD207-001;biotype=protein_coding;havana_transcript=OTTHUMT00000329959;havana_version=4;tag=basic;transcript_id=ENST00000410009;version=3 2 ensembl_havana three_prime_UTR 21 854 . - . Parent=transcript:ENST00000410009 2 ensembl_havana exon 21 1005 . - . Parent=transcript:ENST00000410009;Name=ENSE00001949188;constitutive=1;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001949188;rank=6;version=1 2 ensembl_havana CDS 855 1005 . - 1 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 2 ensembl_havana exon 1506 1624 . - . Parent=transcript:ENST00000410009;Name=ENSE00000760756;constitutive=1;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00000760756;rank=5;version=1 2 ensembl_havana CDS 1506 1624 . - 0 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 2 ensembl_havana exon 2705 2856 . - . Parent=transcript:ENST00000410009;Name=ENSE00000760757;constitutive=1;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000760757;rank=4;version=1 2 ensembl_havana CDS 2705 2856 . - 2 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 2 ensembl_havana exon 3451 3825 . - . Parent=transcript:ENST00000410009;Name=ENSE00000760758;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00000760758;rank=3;version=1 2 ensembl_havana CDS 3451 3825 . - 2 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 2 ensembl_havana exon 5296 5412 . - . Parent=transcript:ENST00000410009;Name=ENSE00001588982;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001588982;rank=2;version=1 2 ensembl_havana CDS 5296 5412 . - 2 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 2 ensembl_havana CDS 5508 5580 . - 0 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 2 ensembl_havana exon 5508 5626 . - . Parent=transcript:ENST00000410009;Name=ENSE00001589135;constitutive=1;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001589135;rank=1;version=3 2 ensembl_havana five_prime_UTR 5581 5626 . - . Parent=transcript:ENST00000410009 bcftools-1.21/test/csq/ENST00000410009/ascii-art.txt000066400000000000000000000001571467060157400212560ustar00rootroot00000000000000 5507 ref CTTG.CT alt CTTG.CCT <-- this one is correct CTTGC.CT iiii.eeeee bcftools-1.21/test/csq/ENST00000410009/frameshift.1.cmd000066400000000000000000000002251467060157400216110ustar00rootroot00000000000000{bin}/bcftools csq -b -f ENST00000410009.fa -g ENST00000410009.gff frameshift.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENST00000410009/frameshift.1.cmd.out000066400000000000000000000002111467060157400224120ustar00rootroot000000000000005507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25E..329>25G..94|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding bcftools-1.21/test/csq/ENST00000410009/frameshift.2.cmd000066400000000000000000000002261467060157400216130ustar00rootroot00000000000000{bin}/bcftools csq -lb -f ENST00000410009.fa -g ENST00000410009.gff frameshift.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENST00000410009/frameshift.2.cmd.out000066400000000000000000000002111467060157400224130ustar00rootroot000000000000005507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25E..329>25G..94|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding bcftools-1.21/test/csq/ENST00000410009/frameshift.3.cmd000066400000000000000000000002271467060157400216150ustar00rootroot00000000000000{bin}/bcftools csq -B 5 -f ENST00000410009.fa -g ENST00000410009.gff frameshift.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENST00000410009/frameshift.3.cmd.out000066400000000000000000000002211467060157400224150ustar00rootroot000000000000005507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPK..329>25GASSQ..94|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding bcftools-1.21/test/csq/ENST00000410009/frameshift.txt000066400000000000000000000017531467060157400215350ustar00rootroot000000000000005507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP*>25GASSQVRSISGPGENTHSPCCINLPDAGPGRLRPAAGRPLSPVYGHHIRCKDQCPVAERSCGQHQHPGF*|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding 5507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP*>25GASSQVRSISGPGENTHSPCCINLPDAGPGRLRPAAGRPLSPVYGHHIRCKDQCPVAERSCGQHQHPGF*|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding bcftools-1.21/test/csq/ENST00000410009/frameshift.vcf000066400000000000000000000016001467060157400214630ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 5507 . G GC . . EXP=frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP*>25GASSQVRSISGPGENTHSPCCINLPDAGPGRLRPAAGRPLSPVYGHHIRCKDQCPVAERSCGQHQHPGF*|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding;type=ENST00000410009:71062833-G-GC, ambiguous, can be frameshift or a splice bcftools-1.21/test/csq/ENST00000413103/000077500000000000000000000000001467060157400166345ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000413103/ENST00000413103.fa000066400000000000000000000032141467060157400207510ustar00rootroot00000000000000>1 1:94713444-94715068 GCGCCCGGCCTGAAGTTGTCCCAACCGCGGCCGCGTCGGTCGCCCTTTTGACTTGCAGCA GGGCGGGCAGAGCGACTTAGAGGAAAAGTGACTTTTTGTACCCTCCTGCAGGGAGCAGGT TCTCTGTCCTTGTTTAATTAGACATTTCTCAGGTGGGCACTTTGAATTCCTTCCAGTCAA GACTCAGGTGTTCAACTTGTTTTGTCGGCCGTCTTCCTCCACCCTTCTTCTCCCATTCAA AACAAAAGTACGTTTTGTGCTTAACTTTAAAACTCCCCCCACTCTTTTCTGTCTTCAACT GATTGTCACTTTCAGCAAACCAAATAAATTACTCAAAACATCAGCTATTATACAGTCCCC GACACATGGCAGGTGCTCAGTAGATGCTAGTTGATCGCATGTCCCCTAACCACGCTACCT GCTTCTTACCATTAAGTGCTCCTTCAGTCATGGGACTGATCAACACGGTGGAGGAAGCCG CAACCAAAATAAAACATTTATCTAGATGTTGGATCACACATCATATCATGTATGGAGGAA AACAAAACACTGCATTTATATATAATATATATTAGTAACACTTACCAACTCTACTAAGAA TACCTTTCCTGTCACCTGTGCTGACACATAAGCACTCCATGAATATTAGCTGATTAATGG GTAAAATTATGGAAAGGGAATTTGGAAAAATCACTTAATGGCATCTTCCCTTTAAATATT TTTCAAAAAGATTAAATATCTGTCATATTCTTCACCCTTCTTCGTTAGGAGAAATATATT TGAAAACATTGTCAAAGGAAGATGTTTTTGTTTTGTTTTGTTTTGTTTTAGAGAGAGACA GGGCCTTGCTCTGTGCTCAGGCTGGAGTGCAGTGGCACAGTCATAGCTCACTGAAGCCTT GAACTCCTGGACTAAAGGAATACTCCCATCTCAGCCTCCTGAGTAGCTGGGACTACAGGC TTGTGTCACCACACCCAGCTAGCTCTGTTGTTTATTTTTATGTTTTGTGGAGATGGAGTC TTCGCCATGTTGCCCAGGCTGGTCTCAAACTCCTGGCCTCAAGGGATCCTCCTGCCTCAT CCTCCCAAAGTGCTGGGATTAGAGGCATGAGCTACCACACCTGGGTCATTTTTATAAGTA AATATGATTATTAACTGAGAAAGGGTGAATGTCAAACATCTGCTATGTGGGATAAATGGC TGTGTTTGGCAAAGAAACTAAAAAATAAGGGGCAATATCTCCACCAAATCCTCTAACACT GACTCAGCATGTGCCCTGAATCATCTTATAAGCCAACTAGGTTTTTTACCTATAAATGTT TCTTCACTAAAGTGGCTCATGATCATGGTTTTGGAGGACGAGGACTAACAGACACACAAA CAAGAAATCAAAGGCATAACTGGATAGTGCATTAATAATGAAGCATGTATGACAGATGAT GTGGTATTGTTATTTTATAATTACAGTATATATTAACACATATCCACTCTGCTTATTGAA ATATTTTTCATTCCTTCCATGATAGAGAATCCTGCCTCTGCTCTGAAGCCTTTCTGTTCG CTCCAGTGAAAATTAGTCATCCACCGGGCGCGGTGGCTCACGCCTGCAATCCCAGCACTT TGGGA bcftools-1.21/test/csq/ENST00000413103/ENST00000413103.fa.fai000066400000000000000000000000201467060157400214770ustar00rootroot000000000000001 1625 23 60 61 bcftools-1.21/test/csq/ENST00000413103/ENST00000413103.gff000066400000000000000000000013361467060157400211300ustar00rootroot000000000000001 havana lincRNA_gene 21 1605 . + . ID=gene:ENSG00000231363;Name=RP11-148B18.1;biotype=lincRNA;gene_id=ENSG00000231363;logic_name=havana;version=1 1 havana lincRNA 21 1605 . + . ID=transcript:ENST00000413103;Parent=gene:ENSG00000231363;Name=RP11-148B18.1-001;biotype=lincRNA;havana_transcript=OTTHUMT00000029383;havana_version=1;tag=basic;transcript_id=ENST00000413103;version=1 1 havana exon 21 152 . + . Parent=transcript:ENST00000413103;Name=ENSE00001743123;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001743123;rank=1;version=1 1 havana exon 1526 1605 . + . Parent=transcript:ENST00000413103;Name=ENSE00001669492;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001669492;rank=2;version=1 bcftools-1.21/test/csq/ENST00000413103/long-deletion.txt000066400000000000000000000001651467060157400221370ustar00rootroot0000000000000017 TGTCCCAACCGCGGCCGC T non_coding|RP11-148B18.1||lincRNA 17 TGTCCCAACCGCGGCCGC T non_coding|RP11-148B18.1||lincRNA bcftools-1.21/test/csq/ENST00000413103/long-deletion.vcf000066400000000000000000000007061467060157400220770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 17 . TGTCCCAACCGCGGCCGC T . . EXP=non_coding|RP11-148B18.1||lincRNA;type=ENST00000413103:94713460-TGTCCCAACCGCGGCCGC-T, starts well before ex_beg bcftools-1.21/test/csq/ENST00000420190/000077500000000000000000000000001467060157400166405ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000420190/ENST00000420190.fa000066400000000000000000000471711467060157400207730ustar00rootroot00000000000000>1 CAAACTCTGCCAGGGCAGCAAGGGCCCGTCCATCCGCCACCGCGGCGAGTGGCTCACGCC CAACGAGTTCCAGTTCGTCAGCGGCCGCGAGACGGCCAAGGACTGGAAGCGCAGCATCCG CCACAAAGGTGCCGCCGCCCCTCCCTTCGCTGCCGGGACCCGCGGGCCCCGACCCCACCC CCTACCCGACTCGGACACCCGGGAGCCTCCGGCTCGGCCGAGGGGGCGCTGCAGCTCCAG GGCTGCGCGGGGACACCCCCGCCGCGCGCGGAGGCCTCGGTGAACACGGACAGATCGCCC CCCGCTGCACCTCCCCCCAGCTTGGGCCACAGCGCTTGGGGCTCGCGGGCCGCTCCCTCC GCTCGGAAGGTCTCTGCGAGGCTCCTGGGCCTTAAGGCCCGAAGGAAGTTTACGGGGACT CGAGAGAGCGGGCAGGAGGCGGGTTGGGAGGGCGCGGAGCCCCGGGTTCGGGGGAGACTG GAGGGGCGCACGTGCGGCCGGGTGCGAGCGCGCGGCGGGGGAGGCTGCGGGGCGGCGCGG GGGCGCGCGCGGAGCCCGAGCGGCGGCGCCAGGTCACACAACCTGTTTTGGCGCCTGCGG GCGCCTGGGCCCAAGGGTGCGACGCGGGGGCGCCTGAGCCGGGACACAGGGGGTGCGGTG AGCGCCAGGCGCCGCGGGGAGTTAAAAAGTTCGGGACCTGAGCGGTGCGTGGTTCCGCGG TGGCCGCCTCTTCCTGCCGCGCAGGCCGAGGGTCCCGACGGCGCCGCTCACCGCTCCGGG ACTCAGCCTTTCTGGGCCCGGCCTGCGGTTCCCTCGGGGCCGGGGAGAGGGTGGAGCGCG GGAGGAGGGGCGCCGGGTGGGGACGCCCAGGCCCTTCGTCGGGGGAGGGCGCTCCACCCG GGCTGGAGTTGCAGAGCCCAGCAGATCCCTGCGGCGTTCGCGAGGGTGGGACGGGAAGCG GGCTGGGAAGTCGGGCCGAGGTGGGTGTGGGGTTCGGGGTGTATTTCGTCCACGAGCCGG GGAGGGGGTACTGGCCCTGCCGCTGACTGCGCGCAGAAGCGTGCCGCTCCCTCACAGGGT CTGCCTCGGCTCTGCTCGCAGGGAAAAGTCTGAAGACGCTTATGTCCAAGGGGATCCTGC AGGTGCATCCTCCGATCTGCGACTGCCCGGGCTGCCGAATATCCTCCCCGGTGGTGAGAT GCGGGGCTCGGTTGGGGCTGGGAGTTACTCTCCCCTGCGGAGCTTGTCCCTGCGGTTTTC AGGGTTTTCAGGATCGAGAGTCCTAACCTCACCCCTGCGGGTGTGCTGGAGGGAGCCTCC GAAGGGCAGGGGGAAGCGGCTTTACCTCGTGCTCTCCCAGCCCTTCTACCTGGACGGGGG AGGAGTCCTCGGGCACCCGAGCGCCCTCCCCGGTGGAGACAGGGGGGCCGCGCTTGTCTT AGAGCCTCCCCTTGGGTGCCTTTTAGCTGCTTATCCTCGAGTCCTGGGTCAGGGTCTTCT CCCTGGGAGGAGTAATTCAACGTGGGCCTGGCACTGTGCCCTGTCACCGCTTGGGGGTCA CCGTGTTCTCTGGCCCAGCTGGTGAGGTGTGATTCTGGGACGACAGCATTTTGGGGAGCT ACAGGCTTGGGTGTGAGTGACTTGTGTCTCTGGGTGCTGAAGGCCAGAGGGTGCAAGGGC CTGGACGTCGAAGTGTGTCCTAGGGACGCAGAGGCTAGCCAGGGGCAGAGTCTTTGCAGT GTGGGCCTTTGGTGTCCAGGGAACTGGAGTCGGAGGCTGGTTCAAGGCCCCAACCCAGGG TAGACAGCTATGGACACCCTCACTGAGGGAGCAGGCAGGAGAGACGGGGATGCTGGGAGC TGCCTTCTGCTCAGGGAGGCACCTGCACCCCCTACCCAGTCTCCAGCCCCCTAGTTGGGC AGCAAGGGTTAGAGGATTGATCTGAAAAGGAAGAATGCCTGTTGGGAAGGACTAGTTTGG AGCCAATTAGGGCCATGGCTGCTGGGGGTGGGGGCTGCAATTCCTGACACACTCAGGAAC CCCTTCTTCCAGGAAAGGGTAGGAGAGGCAGAGGTGCAAAATGGGCCTGAGGGTCCCGGG CGTACCTCCGCTTGCCTGCTTTGGGCCTGAGGTAGGATGGGGGAGGGGATGCCCAGGGGC CTGTGAGCCATGAGTGCCGTAGCCAGGGAGCTGGGCGGCTGCAGACACACCTGTGAAGAC GGCTGGTCCCTCAGACATACAGCATGTTGGGCAGGGGAAGGGGACACAGCCGCACCTCAC CCATGTGCCCACCTGACACACAATCCGACATGGACCTGCACGCACAGGCAGGCAGCTCAC AGAGTTCCCAGGCAGGTGTGCAGACAGCCGGCAGCCCCCTGTCTGCTGTCACAGACCTAC CCGGGGCAAGAGGCCCAGTTCCCTCCTTTCAAGCAGCTGGTGCTGGAGAGGGCTCCTCTG GGCAGCCCGCTGCCTAGCCTTGGGTCTCTGTTTGGATTTGAGCGGCCCCCTTGAGGGCTC CCCCAGGAGTGGGGAGCACACAGCCTGAGCCCAGCGTCAGTCTCTTCCGACAGTGCTTCC GTGAGCATCTCCTCCCCACCCCGTGGCCACAGCCAGGAGATGCCCCCCCACCTGGGGCTC CCAGGTCCCTGCCCTGCGTGAGGGACGGCTCAGATCCAGGCCTGCCTCTGCCAGTCCCTC CCAGGCCTGTCCCACACCCTTCCCCTAGGAAGCAACTCCAGGGGCCCCTTCTTTCCAGCC CCCATGTTTCTTACTCAGAGGCTGTCTCCCCCAAGCCCCATGCCAAATCCGCAGGCATGT GCACCTCATGGTCACAGATGCTCCGGGGCAGAATATGAGTGTGTATGTGCCTTGGGGACC CTGCACAGGGGCCCTGCAGGCCAAGCACCTTCCAAGAGGAGGTGCTGTCAGGGGCCGAGT TTTCAGATCTGTGTGCTGTGGCCGAGGTCTCTAGTGTGGAGGAGGTGTGTTCTGTCCTTG GGCAGGGTGGGTGGCAGGGAAGCTGTCCTGGTCCTCAGCACCCCCATCAGCCACTCCAGA CCTGCCCTCCAGGTGCCTTGGGGCGTGGCTGGGGTGCCGGTGTGTCCCCACGCCCGACTC TGCGCATCACGGGGCTGAGGCTGGTATACAGCCTGGGCTCCATTCCCAGCCAGCCCTGGC CTCCTTCCAAGGGGCAGTCTTCTGGTCCTTGCTTCCCTCTCTTCCCCATCCCACAGACAA GAAGCAGAGAGCAAAGCATTGTGTCTTCTCCTCAAAAGAAGGGAGGTGGGAGGCCGGGTG TGGTGGCGCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGT CAGGAGATCGAGACCATCCTGACTAACACGGTGAAACCCGTCTCTACTAAAAATACAAAA AATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGG AGAATGGCATGAACCCGGGAGGCGGAGCTTGCAGTGAGCCCAGATTGTGCCACCGCACTC CAGCCTGGGCAACAGAGTGAGACTCCGTCTCAAAAAACTAAAAAAGAAGAGAGGTGGGAG AGGAGAGGCTGTCAGAGCCTCTAAGCCCTGGTGCTTGGGCTGCAGAAGGGCAGAGCTAAG CGGGACTTCCCAGCACAGCACACTCCGGACAGGCTGTGGCTGTTGAAGGGACCCCCGAGC TCCAGCTGACACGCGGAGGCCCGGGCACAGACAGGCATCATACCTTCGGCCTTGGCCGCA CTCTGTGGTCATTGGTGTTGGGGGCAGCCCAGGGTCAGGGCAGGGTCTCAGCCTCGGACC CCAGGCCCCACCCCTTGCCCAGCAGTGCTGCGTTTTCCCAGTGAGCTGTCGTGGAGAGAG CAGAGGGGACCCAGCGCAGGCCCAGTGGCCGGTGAGGGGAGACGTGGCTCTGGGACGGGG GCCTCCACCTGGGTGGGGGGATGCTCCAGCTTCCAGACCCTTGGGGAGGGGGCACTGCCC AAACTAAGCTGGCACTGGGGCTGTGCATTTGAAGGTGATGGTGGTTCTAGGTCTGAGGAG GACACCCTCCTAACAGCCTCATCCCCAAGCTCCGGGCTGTGTTGTGGCAATGGGAGGGAG GAAGTCTGAGGAGACCCTGGTGACTGAACGGAGGAGGGAGTGAGTTAGACGCTCTCAAGG GCTCTGCCACCTCCCGGAGCCAGCGGCCTGTTACTACATTTAAAAAAGCCTCCCGCCCAC TGGAAAATAATCAATAACTTTCCTTTATCCCTGGGGGTGGCAGGACCTAGAAACACTGGA GGAGTCCGGAAGTGCCTGGGGCTGGGCCGGCGCTGGTGTGCTGTGCAGGGTGCCGCGGGC ACGTCCGCCGCGTGTGTGCGTCAGCTCGGGGCTCGGCTGTGCTCTGCAGGGACCACAGCG GGCGTGTCTGTGCTCCCACCCGAGGCACCCACAGCTCCACACGCTCGTTCCGTGGGTGCA AAGGAGATGGGAGAAAGAAGCCCTGTGAGAAATGCGGGGCAGGGTTTGCGGAACAGGGGA CCTGGGCTGGTGAGGGCTCCTCGTCTGGTGACCTGTGAGCCCCGGGGCCTGCAGTCTGCG AGGGTTCAGCTCAGACAGTTGCCAGTGGCCTTGCACCAGGCTGCAGCTGCCCCTGAGCCG GGCTGTGCGTGGCGCTGATGAAATAGAAAAGGGCATTCGCTTGTCAACGTTGGCATCGGT GGCAGGGTGTGGTGGGCAGAAGGGTCACAAAGTACGGGTGGGATTGGCAGGCAGATACAC GGAGGGAACGTGCGCATTTGAGTGCACGTCCACCAGCACCAGCCCCAGGCCACAGGCAGA TCCCAGGAGACACGCAGGGGCCCTAAGAAGGGAGCTGGGAATGAGGGGCCACACAAGCCC GGGACGGAGGCCTGTCGCACATGGGGTGGCCCCGACTCAGGCCCTGGAGTTGGCCAGGAC CCTCTAGCATCCTCAAGGGCTGGGCCAACCAGGCTGGCGTGGGGTGGGGCAGGGGAGGGC TGAGCCAGTGGGCGTCGTCTGTAGGGGGATGCCCAACTGCGGCCCCGTCTCTCGGCTCTC CTCTGGGTCTCTGGCCAGCTGTGGCTCCTGCTGGCCCCAGGCGCATCCCAGAGGCAGGTA GAGGGAGGATGGCTGCTCTGAGGGCACCTCTGCCGTGCTTGGGGCTCGGCCTGGGGTGCG AGACCAGGGCAGACCCCCGGGAGATGGAACGGCCCGGTCCAGCCCCACCTTCCTCTCCTC CTGCCCCACCTTCCTCTCCTCCTGCCCCACCTTCCTCTCCTCCTGCCCCACCAGAACCGG GGGCGGCTGGCAGACAAGAGGACAGTCGCCCTGCCTGCCGCCCGGAACCTGAAGAAGGAG CGAACTCCCAGCTTCTCTGCCAGCGATGGTGACAGCGACGGGAGTGGCCCCACCTGTGGG CGGCGGCCAGGCTTGAAGCAGGAGGATGGTCCGCACATCCGTATCATGAAGAGAAGGTAC TTGGACCAGGGCCGGACAGGAAGGCGCAAGGCTCAGATGGGGCTGGAGCTTCAGGCCTTC AGCTGCTCAGATGAGAGTGTCCACACCGGCCTCCCACACCTTCCCTCAGATGCTGGTCTT TTTGGGGTCCTGTGTGGGTCGCAGGCAGGAGCTGTTTCCTCATCTGCCCCCTGTCTGGCG TCCCCTCCCACCTCTGCTCTGCGGCGCTCACTGGCAGAGGCAGGTTGGCAGCAGTTGGGA CCCAGAGGTCTGCACCTTCCTGGGCCGACGCTCCAGCTACCCTTGCTGACCGGGTCCCAG TCTGGCCAGAGAGCAGCTCTAGCAACAGGGAGCTCCATTCAGGCTCGTGACTGGCTGTGC AGAAGCAGCCTCGGCCCCCACCTGCGGTACAACAGGAGGGCTCCTCTGAGTGCACGGCAA CAAGCAAGAGGGAGAAGGGGCCTCGGTCCTGTTCTTCCTGATGCGTGTCTGCTGAGGCCA GGAGCTGGCTTTGGCCCATGGGCCTGTCCTAGTGGGAGGCCCCAGCATGTTGAGCCAGTA GCAGGTGGTGCTGGGCATGGCAGCCGCCCTCGTTCACTGCCCAGGGCTGTGGCCCAGCGG GGCACTGACCCGAGACAGGTCTGCGCACGCCCTGCTATCCTGAGGCTGGGGTCAGGGGCC TCCAGAGCAACATGGACCTTCTGCTTCCCTTCCTGCAGAGTCCACACCCACTGGGACGTG AACATCTCTTTCCGAGAGGCGTCCTGCAGGTAGGAGCCGTGCTGTGCGTGCATAAGAGGG GGCCGTGACTCCCCTCCCTCCCTCCCACCCCTGACCGTGCCCTGCTGTCTGCTGTCCGCT GTCTCAGCGTGAGCTGATGCTGTGATGCTGGCTGAGTGTCTGCCAGGTTTGACATGTGCT GCAAGGTTGTCCCCCATCCCGGGAGGCAGACAGTGTTGCACCCAGTTGGGACTGAGGGAC CCCAGACCCAGTCAGATGCAGCTCTCGGCAGCAGCTCAGGTGTGAGTTCTGGGCAGCCCG GCCCTGGAGTTAGAGTGCACTTCCTCCCATGTGAGACTGGCCATTTGAGCCCAAAAATGA GGCTGTCACCTCCCCCTTCCCACCCTCCTAGAGACCCACAAGGAGGTGAGAATGCTGATG TGTGAGTGGGGCCCTGAAGGGTGTGTAGGAGCTCTAAGGCGAGGGGATGTCTGCAGAGTA GAGGAACAGGGAAGGGCGTGTAGGAGGGACGAGGAGTGAACCTGGCAGCTCTGGTTCAGT TGGATGCTGAAGAGTCATGGATGCTGGGCCTGTGGGCACCGTCCTCCAGGCGGGAGCCAC CGAAAGTTCTTGAGCAGGGCAGTGACCAGGTGTATGTTTGGAGAAGGTCCCTCTGGAGGC CTTCCTGGCAGACAGGGGATTGGATTCAGGCTGTGGAAGCAGGACGGTAGGGGGTGTGAT TCCAGGATGTGGAAAGGAGATAAAAATGAAGAGCCCCGGGGAAGAGGTCAAGGGAGTTGG GGGACCCGAGTTCCTGGCTCCAGGGGGAAGCGAGTGGTAAGTCTGTGAACAGAGCCCAGC TGTGGATTCTGTCAATGGGGTCAGGTCTCACCCTGTGGCTTCCAGGGCAGCAAGGCAGGA AGGAGGCGTCTGCCACAAGGCCAGCTTCCTGGGGCCAGAGCCGTGAAGGCCCAGGGGACC TGCGTGTCTTGGCTCCACGCCAGATGTGTTATTATTTATGTCTCTGAGAATGTCTGGATC TCAGAGCCGAATTACAATAAAAACATCTTTAAACTTATTTCTACCTCATTTTGGGGTTGC CAGCTCACCTGATCATTTTTATGAACTGTCATGAACACTGATGACATTTTATGAGCCTTT TACATGGGACACTACAGAATACATTTGTCAGCGAGGCCTGTAGGGAAACCCAGCCGCGGT CCCCCCGACCCCGCTCCAGTAACGGCTCCTCCTGCCTGCAGCCCCCTCCTCCGTCTGCCT GGCCTCGGGAATGCAGCGTCCCTCGGCAGCACTGACGGCAGACAGCCTGGGGTGCCCTAG GAAGAGGCCAGGTCTTCCATCCTGCACGGGCCCTAGAAGGGGCTAGGATGAGTTTCTGAA TCTCCCAAGGGCGAGATTTCGGTCAGAGGGGAGGGCGTGCTGGGGTCCCCGGAGGAGAAG GCCCAGCACACGCCTGAGTGGACTGAAGCCTCCGCCTGTTGACCTGACCCTGGTGTCCGG TCAGAGCGGGTGGTGGTCCCTGAACCCACACGGGCTCCCAGACCATGTCTGTGTTTCTTT CAGCCTGTCCCTGGGTCCTTCTGCCTCTGCAGGCTCCCACAGAACACACTGCCAGGCCAC CTCCATCTGTGTGTTCATTTGCTCCCGTCCAGTGGTCTCCACCCATCTGTCCGTCTGTCC TTCCATCCCCTTCGCCCTGTCTGGCTGGCTCTGCAGTGACCACCTGCCTTTTGGAGCCAG CGGAGCCCCAGGCCGTCCTCCTCTGCCTCAGGAACCCGGGGTGGCAGATGCTCCTCGAGC CATTGTTTGCAGGCGGGGGCTTGGCCCCTCTCTCCTGGGCCCCTGAGCTGGTGGGAAAAT GGGCAAGGGCTAGGCCGTGTGGTCATCAATGAGGGGCGGTGGCGGGAGGCCCATGCGTGG GCAGCTGGGGTCACACCTGCCAGGCTCTGGCCTCCCCCTCCCCCTCTCCTTCCTGCGCCT CCTGCCCCAGCCCTGACTGCTTCTCCCAGCTTCCCCACCTCCTGACCTGCAGCCCGGCCC CACCACAGAGACTCTCAGGGGCTTCGTCCCTTGTGCGAAGCAGGGTGCAGAGGGCATTCT GTGGTTCGAGGACCATGCGCTGATGTGCCCGGGCCGGGTTCCTGCTTCTCCACTCTGGGA CGTCCAGGGCGTGTTTCTTTACATAAAACTGGCATAACTGGCTCACTGAGTGGCCAAGTG ACCAGAACAGGTTTTCAGGGGCCGGGCCAGGCCAGGCTGTGTCGGAACCTCAGGAGCAAA CTCCAAGGCAGAGACCAGGGGCGGGGAGGGCAGGTGGCACCCAGCTCCCCACCAGGTGCC ACTGCCCAGCCACAGCCCCTCCACCCAGCTATTAGGCCCTCCCTCACTTTCCTTCTGGGC GCCAGGCTCGGGGCTCACTGCCAGCCCCCAACCTCTGGAGTCTCTGGGAAACTAGTTCTC CTCCTGCAGGCGTCCTGGGGACACCAGAGGGGGGACCCCTGGGGAGAACTCCATGGCAGC TGTGGCTACTGCCAGGCCAGCCCTCAGCCCCCACCCCATGCTGAGGCCAGCAGTCCTCTC CTGACACCCCCGCGTCGATTAGGATCATGGAAGGGATGAGTCTCGCTGCCGATTAATCCC ATAAAGTACTTACTCCCACCCAGCTGCCTTCCTATGTGCCTGGGGGGGGCTTCCTTTCCC ACTGGGAGCCGGTGGGGGTGGGGGAGAGCCGTCATCTAGGTCTCCTGGAAGGTTTAGAGC CCAGCCTGGGAGTCTTTGGTGCTGAAACGGATCTGCTTAGGGGCAGCCTTGGATTAGCCC AGCTCCAGCCAGCCCAGGTCAGGGGAGCCGGGAGCTATTTAACGAGGTTTAGGGTAGGCT CCTAGGTCACTGCGCAGGACTGCTCCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACA GGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTG GGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTCCGTTACAGGTGGGCA GGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGG AGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTCCGTTACAGGTGGGCAGGGGAGGC GGCTCCGTTACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCT GCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGT TACAGGTGGGCAGGGGGGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACA GGTGGGCGGGGGAGGCGGCTCCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTG GGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGGGGCGGCTGCGTTACAGGTGGGCG GGGGAGGCTGCTCCGTTACAGGTGGGCGGGGGAGGCTGCTCCGTTACAGGTGGGCGGGGG GGGCGGCTGCGTTACAGGTGGGCGGGGGGGGCGGCTGCGTTACAGGTGGGCGGGGGAGGC GGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTCCGTTACAGGTGGGCGGGGGAGGCGGCT GCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCAGGGGAGGCGGCTGCGT TACAGGTGGGCAGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTCCGTTACA GGTGGGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGAGGCGGCTGCGTTACAGGTG GGCGGGGGAGGCGGCTGCGTTACAGGTGGGCGGGGGGGGCGGCTGCGTTACAGGTGGGCG GGCGGTGCTGCAGGAGGACTGCTCAGGGAGTGGCGCCTGGACCCTGAGCCCCTTCTCTGC TGACTGGGGAGAGGCTCACGGAACCGGGAAGGGGTGGAGGGCCGTGCTCCACACAGTTCG TCTCATTGCTCTCTGGGACTCTGTGGATGTGGGATTGGGCTGAATTAGCAAGAAGAGGAG AAATGAGGGAAGAAAAGAGTTAAATGCATGTTGATTCCAAGCCCCCGCCTGCCGGGGGGA CAGCGGGAGGTTGGAGCACGCAGCCCTGGTGCCTGGTGCGAGCTGCACGTGTCTGCCGGT GCCGTGTGTGCGTGGGGCGCGTCTCATCAGCTGCAGGACTGTGGTCTGGGCCTCAGTTTC CTCGTGTGCAGAAATCGGGGGTCAGGGGATGGTTCACATGTGGCACATTCTCTCCTGGGG CCTGTCCTGCAGGACTGCCCCTGAGCAGATCGGCCTCTTCCCGGGCGCCCGGTGGGCCCC TCGACCCCCTTTGAGGCAGGGAGTGAGATAACTGTGATTCCCTGTGGAGGGCGTGAAGGC AGAGCCGGCTGGCTGCTCCACATAGACCCTCCCTGGAGCAGCCGTGGGGTCCCAGGTCCC AGTGCCAGGTTCTGTGTCGCTTTGACTCGGGTGCTGCGTGGGTGTGCACACAGTGGCGTC ACGGGCCACATGCCGAGGCGTGGGCACAGCAACGTGGCACTCAGAGGTCATCCCCACGCT CACACACAGAGCTAGGCACTCCCTGTGCCCAGGCTGGGCTCCAGCCTCGCAGCTGCCCAC GGGGTCAGCTTTTCCCGGTCTCGTTCTGCAGCCAGGACGGCAACCTTCCCACCCTCATAT CCAGCGTCCACCGCAGCCGCCACCTCGTTATGCCCGAGCATCAGAGCCGCTGTGAATTCC AGAGAGGCAGCCTGGAGATTGGCCTGCGACCCGCCGGTGAGGAGCACAGGGGGCCTGAGG GCGGGGTCGGGGCTGTGGGGCCAGAGGACGGTGGCGTCTCCACTCAGCACCAGCAGCCTT GGCAGGCAGCCAGAGAGGCAGGAGGAGCGGCCTGTCCCCCAGGGGCTGCATGGGATGGTA ATTGTGTTAATCCCAGCCAGCGGGGCAGACAGGAGGCAGAGGCGGTGGCTCCGCTGTGGC TGCCGCTGGGGTGGGCTTGGAGTAGCCGGGGCCCTGCCACCCCCTTTCCACAGGGCAGAC GTAGGCGTGGCCTCAGAGGTTCAGAAACGCACACCCTGGAGGAACGCACGCACTCCCGCA GCGCACGCATGACTGGTCCCGCCTCCTAGGGCTCCTGGACGGAAGGGGTCCCCGGTCCCG CCTCCTAGGGCTCCTGGACGGAGGGGGTCCCCGGTCCCGCCTCCTAGGGCTCCTGGACGG AAGGGGTCCCCGGTCCCGCCTCCTAGGGCTCCTGGACGGAAGGGGTCCCCGGTCCCGCCT CCTAGGGCTCCTGGACGGAGGGGGTCCCCGGTCGGTCCCGCCTTCTAGGGCTCCGGGAAG GATGGGGTTCTCGGGAGGGAAGGGATCCGGCGCCTGAGGGAGGTGCTGCTGCCTGGTCAC AGTTGTGGGGGGACCAGGCCCCCCTCAGAGGGCACTGCTGTAGAGAGGGGCACAGCAGAG CCTCAGCCCCAGGGCAGGCCGTGAAAGGAGGCGGGGGCGCCCCGAGGCCCTGTGGACCCC AGGCAGGGGTGTTCCCAGCAGGGCCTGCATCTCTTGGGAAGGAGGGGTGGGGGAGGCCCA CCCCCATCTGTGTCCCCCATCCATGGCCCCCATCCGCGTCCTCGTGCACCTAGGAAGGCC CTTGTGGGGCTGGGTGGGGGCAGCTTCTGATGCCGCGTTGGAGACAGCTGAGAGGCGGTT GATAAAATCTAATTGCCCCATCGATCCAGCAGAGCGGAGGGAGCCCCACAATGATTGAGA TATTCTGAGCCAGCAGGCCCTCCCCTGTGCCTTCACACAGGGAGACCTCCTCAGGTACAC GCGTGTGCGTGTGCCGGCATGTCTGTGTCTGGGGTCCTGTGGGGTGCACGTGATGGGGGT TGCCCGGCAGCTCTCACCCATGGAGTCAGGACGTGTTCGTGCACTTCCGGGCTCACAGGC TCTACGGGGCCTCACGTGTCCTGGACCCGTGTCCAGGTCTCCCATACGCACTCCGTGTCA GGGTCTGGCCCGCTCCCCGGAGCCTCCTCTTGGAGGGGCATTCACCCTGGGGGGCGTTCA CCTCTTCTCCCTTCCTGTGACCCCAGGAACCACACATCCATCCTGTTCCCAGCCCGGGCC CTCCCGCTAAGCCGCACCTCCCTGGGCCCTGGGCTGTGAGGGACTCAGAGCAGGTCCTGC ATCTGCCTCTGTGAGACCCGCTGGGGTCCATGAGTGAGGAGTGAGCATGGCCTCATCGGC CTTCCTGCGGTCTCATTGCAGGCCCCCTTCCACCTGCCCCCCCCCCCACCCAGTCACCTC CCCCAGGCTAGGAGGAGGCCTTAGCCCCCCACAGAACGGAGAGGGTAGTTTCCACTGTGT ACAATGGAAAAGTGATTGCCAGGAGGTGAGAGGCCTTGCTAACCCTGAGGGCATGTGCAT GGTGGGCCAGGTGGCAGGTGTGGAAAAGAGCCAGGTTCCCCCAGCCTTGGCCCACCCCCT CCCAGCCCACCGAGCTCTGGCACGGGAGGCTGTGGGGGAGACGATGGCTTCTCAGGGGCC TGAGCAGTGGTGCCTGGATCCGTGTGTGGCCAGGTGCCCCCCGCCGCCCGCCGGGCCCAG CCACCCGATCTGTCACCGAGGTGGGGACCCTGGACCAGACCGTGGGACTGACCCTCTCTC TGGGGCCGGGCCTGACAGCAGCCGGGCCAGGATCAATAAGTTATTAGCACCACTCTGTCA GCTGTAATGTGGGATTGATCGGTGTGGCCGCCGCACTTCCCCAGCCTGATAAAAATGACA GATTAAGGGAATAAGAAAAAGGAATTAGGCCTGGAGCTGACGGCAGGGCTTGTGGGGGGA CGGGCTTGGGAGCCCCACTGCCTAGGCCTCATGGAGGTCTTGGGTCACAGGGGAGTGGCC CCTCACTCCACCCAGCTAGAGCCCTCATGAGGATGAGGAAGGGCCAGAGTCGGAGGCACT GGCTGGCCTGGGAGACCCCCAGGGCGTGGAGTCAGGGGCTTCGGAGGAGCTCGGGGTGGG TCGGAGATGGGTACATGGATGGTGTGGTCTGGAATGGGTGCGGTCGGCAGGACCCAAGGG AGGACCTCAGGAGAGTGAGCTGGGCCTGGCCTGGGCCTCCCCTCTGCCACCTGCTGGGCT GTGTTTGGGGCTGAAGCTGGACCTGGCCTGGGCCTCCCCTCTGCCACCTGCTGGGCTGTG TTTGGGGCTAGGGCTGGGCTGGCCTCGTGGCTGAGGAGGTGGGTGAAGCTACTGGGAGGT GCACCCCAGAAGCCCAGAGCCTGGCTGGGCTGGTGGACAAGGGCATGACAGCCACGCCAG GGTGCTAGCTCAGGCAGGACTGGGCCAGAGAGGAGGACGTGGGCCTTCTGGGGGCAGGGA TGGGTATGACCAAGTAGGAGGCCTGGGAGTGGAGGCGCCTCGAGGCGGCCTGGGGGGCCC ACAGCCCAGTGACTCACAGAGCAGCAAGAGGTCAGGTGTGAGGTCCTTCCCGGCTTGTCT CACCCCACGCTGGCATGTGACCCTGCACAGCCCGCCCTCACTCCTGTCCAGGAGGGGAAG GTGGTGCCTGGTCAAACCAAAAGCTTTTTATTCTCCTCTAGGGGGATGAGAGGGGGGCTC GTTAACTTGCACAAGAGGCTAGATGGCGGGTGGGGCAGCTGGGTGCCTGCTGTGGATCTC TTCTGCACACACGCACCAGGGCCAGTGTCAGAGCTCCCCTGTGCCCCTGTCCCGCCACAG CCAGGCGTGATGTCCTCTGCGCTGAAGGCTGGGGCTGCCAGGGCTGGGCAAGGCCTGTAC TCACCAGGACCAAGGGCCCCCTGAGAGATGGTGGGTGCGGTCCAGGCTGAGCTGGAGCAG GGGCTGGGTTCCCCTTCCATTCCTTGAGATGCAGGTGGGCACTCACTACCCTCCCGCAGG TGACCTGTTGGGCAAGAGGCTGGGCCGCTCCCCCCGTATCAGCAGCGACTGCTTTTCAGA GAAGAGGGCACGAAGCGAATCGCCTCAAGGTAAGAGCGTGGCTGGGACGAGAGACAGGTC ACCAGGGGAGGGGGCAGTCCCTGAGGGTCCCCTGGACCTCGAGCAGGCACTCTAGAGGGG CGTGGTCCTCGGCAGTGCCTGGAGAAACCTCTCACCCCGGGTCCTCCCCAGCAGAGGCGC TGCTGCTGCCGCGGGAGCTGGGGCCCAGCATGGCCCCGGAGGACCATTACCGCCGGCTTG TGTCAGCACTGAGCGAGGCCAGCACCTTTGAGGACCCTCAGCGCCTCTACCACCTGGGCC TCCCCAGCCACGGTGAGGACCCACCCTGGCATGATCCCCCTCATCACCTCCCCAGCCACG GTGAGGACCCACCCTGGCATGATCTCCCCTCATCACCTCCCCAGCCACATGTACTCGGCC ATTCCTGTTGCTGAGGCCCTGCTGACACCAAGGCCAGGCTGGATGCAGGTCCCTCTGCCA CACGTCCTGCCCCATGCCCCCTGGGGCGGGCCACACCTCCATGTCCCCTAGGTCCCCAGG GTCATGACTAGCTCACATTTTATATAGAGAGAAATGGAGTCTGGGGTGGACCCAGGTGAG GGTGGGCAGTGGGCATGTCAGCAGCACCCCCCGAGGAGAGCAAGCTCCTGGACCCTGTGG TCTGTGAGTCGTCTATGCAGCCAGTGGACGCCGACCTGCCAGACGCCTGCCCCAGGAGCC TGGGGAGGGGCAGTGAGCAGAAAGGCCGGGCTGGGTGCAGTGGGCACTTGGCCACCAGGA CTCCCCAGGTGCTGAAGAGACGCCAGCTGGAGGGGCTGCCCCTTCCCCCGGGTCGGCCCT GACCCTGTCCACCCCACCTCAGGACGTTCTCCAGGGGTCCCTCCGGGATGCACTCGGACC CCCTGCCCGCTGCACTCAGCCTCCCAGGCCCCAGCCGCCCGCCTGGCAGGGGAGCTTGGC TTTTCGGGCTAGAGGTGGGTGGGGGCGCCGGGAAAGGAGGCAGGATTCCTCACACCAGGC ACCGTCCCCCAGGGCAGCTCAGGCACCAAGAGCCTGAATAATTCACCAAATGTTAATAAT GTAAAAATCCTCCTTTTTAATTGCTTTCCCTGCTCTGCCTGGGGCCGCTCTGCTGGCCGC GCGGGGGAGGGGCGCCGGCCGCCGGGGAGCGCGCTGTCAATCAGGCCGCGCCGCCGCCCC CCCCCCCCGCCCCGCCGCGGAGCCGGCCGTAAATAACCCTGTAACTAACCCGGCCGCTAG CGCGGGGGCGCTGGGCCCCGCTGGGATCGATGCGGGCGGCCGCGCCGGCTGGGCTCTGCG GGCTGGCACCCGGCCCGGGGCGGGACCCACCTCCGCTTTCGGGTAATTAATTTATAAACA GAGGCGGCGGTGGAGCTGGCGGAGCCTGCATAGTGGGGGCTGCGGGGACTCGGGAGGCCC GGGCGGGAGGGAGAGGCCGAGAGACCTGGGACGCGGCGCCTTAGACGCGGGCGCTGCGTG CGCATTGGGGCGAGTGTGGCCACGCGGGACAGTGACCCTGCGCAGCCGGGACTGGGCGAC CCCTGTGCTAGTGTGGCGTGCGTGCGCGGGCGCTGCCTTGCCTTTGTGACAAGCTTTGGC CAGCCGCGTCTACTATGGGGACCTCAGATTTTCTTGCCTCCCACCGAAGAGGGGGTCCCC TGGGCGGTCAGCCCCTGGCTGGCACTTCTGGACTCTCTCGCTGCCCCGCAGGCTCTGTGG CCTCGGGACGTCTGCACAGCCCCCTCCCCGCAAGGCTCAGCCGCCTCTCAGGCCGGAAGC CTCCAGGCACCCGGCTCCCCTTCGGGGAAGAGCTTTTCCCGACACTTCCTCGCCCAGCAT CTTGTCTGCCGTCTCGGCCCTGTGGCCGCCCATCCTCCTGCCCCGTGCCCGAGACCAGCC CAGGGGCCGAGCACGGCCGAGTGGTGTGGTCAGTTCCCCACCTCAGTGTTCTACGCCAGG ACGCGGGCTGGGGAGGATGAGGGCGCATAGCCGGGGGGATCACTGCTGTTGTCCCCCACC CAGATCTCCTGAGGGTCCGGCAGGAGGTGGCGGCTGCAGCTCTGAGGGGCCCCAGTGGCC TGGAAGCCCACCTGCCCTCCTCCACGGCAGGTCAGCGTCGGAAGCAGGGCCTGGCTCAGC ACCGGGAGGGCGCCGCCCCAGCTGCCGCCCCGTCCTTCTCGGAGAGGTACTGGGGTGGCT GCCGTTCTCTGCTTGTTTCTGGGGTGCCGCCCGCACCCCCGCGCTCTCAGCCACCAGCAC GCGCCCCGAGAGTGCCAAGCACTGTGTTCAGCTCTAGGTTCGGGTCCGGGCAGAGCGTTT CGGGGGTGACACCGATCTGGGCTGCAGTGTTGAGGGCGCCACTGGGGTGCGTGAGGGAGG CTGAGGCCCATCAGGGGGTTCCCTGGAGGAGAAGCCAGAGAAGGGGAGAGCTCCAAGTCT GGAACCCCGGGGTCAGTCGGGAGGGGTCGGCCAGAGGACTCAGAGCTGGAGGCGGAGGGG GGGTCCTGGCTGGCGCTCAAATGTAGACGCCGGCGCCGGATCTGTTCCCGGCACAGACAA GGCCTCCGGCACAGACCCGGGTTTCTCGGGTCCAGGACACGAGGCGGGGCGGGGCGCCTG GAGAAGGGAGGGGCCGCCTGAGGCCCGAGTCCCTGCCCGGCCGCTGAGCCCGGCGTCTGC AGCTGCCTCCACCGCCGCCCGGATTGCGGCTAATGACGCCCCCGCTTCCCCCGCCGCTCG GGTCCGCAGGGGAGGGGAGCAGGCGGGGCCGGCGCCCCGCGCAGTAATTACCGCTGCAGC CGTCGCCGCCCGCCGGGTCAGCGCCTCCGCGCCGCCGCCGAGATTAATTGGCGCCGCCGG CGGGGGCGGGGATGGCGCGCGACCTGGGGCCGTAACGAGCTGCGCATCGACCGCCCGCGG GGCCGGCAATTAGCGGAGGCGGCGGGGGAGGGGCGCCGGGGCCTTTACGGGAACGGGGGC GGGGGGGACGCCGCTCATTGCGCTGCCGTCCACAGGGAGCTGCCTCAGCCGCCCCCCTTG CTGTCGCCGCAGAATGCCCCTCACGTCGCCCTGGGCCCCCATCTCAGGCCCCCCTTCCTG GGGGTGCCCTCGGCTCTGTGCCAGACCCCAGGTGAGGAGGCGGGTGCGCATCCCCTGGGA GCCCGCGTGGAGGCTCGCGGACCCGGCCCTGCCCCTGTCGGAGCCGAGACGGACCGGGTA GGGGATTGCAAAGGGCCGGCTCGGACCGCCTCGGACCCCCCGACCCCGCGTTGTCCCCCT CCCCACCAGGCTACGGCTTCCTGCCCCCCGCGCAGGCGGAGATGTTCGCCTGGCAGCAGG AGCTCCTGCGGAAGCAGAACCTGGCCCGGTAGGTGCGGGGAGGCGGGCGGGGCCGCGCGG CCCGGGAGGCGGCTGACCCGCGTCTGCCCCCGGCCCAGGCTGGAGCTGCCCGCCGACCTC CTGCGGCAGAAGGAGCTGGAGAGCGCGCGCCCACAGCTGCTGGCGCCCGAGACCGCCCTG CGCCCCAACGACGGCGCCGAGGAGCTGCAGCGGCGCGGGGCCCTGCTGGTGCTGAACCAC GGCGCGGCGCCACTGCTGGCCCTGCCCCCCCAGGGGCCCCCGGGCTCCGGACCCCCCACC CCGTCCCGGGACTCTGCCCGGCGAGCCCCCCGGAAGGGGGGTCCCGGCCCTGCCTCAGCG CGGCCCAGCGAGTCCAAGGAGATGACGGGGGCTAGGCTCTGGGCACAAGATGGCTCGGAA GACGAGCCCCCCAAAGACTCGGACGGAGAGGACCCCGAGACGGCAGCTGTTGGGTGCAGG GGGCCCACTCCGGGCCAAGCTCCAGCTGGAGGGGCCGGCGCCGAGGGGAAGGGGCTTTTC CCAGGGTCCACACTGCCCCTGGGCTTCCCTTATGCCGTCAGCCCCTACTTCCACACAGGT GGGCACCCCCACACTCTAGATCCTTCCAGAGGGCACAGGACTGGCAGGCCGCCTGTGGAA GGGTCTTGGGGGGAGGAAAAATTCCCCTTAGGCACCCATCCCCCACCTCAGCAATTGGGG CACACGACGGTCAGGAGACGGGCGGGTATGGGAAAGCCAGCCAGAGCCCTAGTAACACGC CCCACAACTCAGGCGCGGTAGGGGGACTCTCCATGGATGGGGAGGAGGCCCCAGCCCCTG AGGACGTCACCAAGTGGACCGTGGATGACGTCTGCAGCTTCGTGGGGGGCCTGTCTGGCT GTGGAGAGTACACTCGGGTAAGGGGGGGCCCCAGTTCCTGGGGCGGGGCTGGAGCTGGCT GGCAGTCACTACCTCCCTGGAAAGGATGGTGGGGTAGGGCCATTCCCCAACGCCCTCTCC CTCCCCAAAAGCAGTGCGCAGCAGGGACTGGACTGTGCACCCCACCTTTTTTTTTTTTTT TTTTTTTTGCCAGGTGTTTTCTGCCTGACACTCAAACCCAACAGATCACTGTTTTTAAAA AATTTCCGTGAGCTGCACAAACAGCTCCTCTTGGCTCTGCTGGGCTGGAGGATGGAGCAG CACCCGGGTCCTGACCCTCCCTCCCTCCCCCTTCCAGGTCTTCAGGGAGCAGGGGATCGA CGGGGAGACCCTGCCACTGCTGACGGAGGAGCACCTGCTGACCAACATGGGGCTGAAGCT GGGGCCCGCCCTCAAGATCCGGGCCCAGGTGAGACGCTGGGGAGTGAGGTCAGGGTCTCC AGACCACAGCTGGGCAGAAAGCTCTGGGTGGGTGTGCGACAGCCCCCACCAGGCCATCTC TCTGCAGGTGGCCAGGCGCCTGGGCCGAGTTTTCTACGTGGCCAGCTTCCCCGTGGCTCT GCCACTGCAGCCACCAACCCTGCGGGCCCCGGAGCGAGAACTCGGCACAGGAGAGCAGCC CTTGTCCCCCACGACGGCCACGTCCCCCTATGGAGGGGGCCACGCCCTTGCCGGTCAAAC TTCACCCAAGCAGGAGAATGGGACCTTGGCTCTACTTCCAGGGGCCCCCGACCCTTCCCA GCCTCTGTGTTGAGGTTGCCGGGGGTAGGGGTGGGGCCACACAAATCTCCAGGAGCCACC ACTCAACACAATGGCCCTGCCTCCCACCGCTTTATTTCTTTCGGTTTCGGATGCAAAACA AAAAATTTTAAAAGAAAATGTGACTTCAAAGGAAAGGAACAAATTTTCAAAGACTTGGGG GAGTGAAGGCAGAGCCTGGTGCAGATGGACGAGGTCTGCAGACGGAGGGCAGAGGTGGTG GAAGGGGCCAGGGGCCTGCAGGCCTCCCCCTGGAACTGGGACTGGTCTCGGTCTGCTGAC GTCAGGGTCAGCTCCCCCGCGGAGCTGACTTCAGCAGCCCACAGCTGTGGGGCTTCAGCA GCCACACCAGCCCAGCCCAGCCCAGCTCTCGATACGTTTGGTCTTTCATGCTGAAAAATA AATAATAAAGCCTGTC bcftools-1.21/test/csq/ENST00000420190/ENST00000420190.fa.fai000066400000000000000000000000201467060157400215070ustar00rootroot000000000000001 19756 3 60 61 bcftools-1.21/test/csq/ENST00000420190/ENST00000420190.gff000066400000000000000000000050241467060157400211360ustar00rootroot000000000000001 ensembl_havana gene 60 19755 . + . ID=gene:ENSG00000187634;Name=SAMD11;biotype=protein_coding;description=sterile alpha motif domain containing 11 [Source:HGNC Symbol%3BAcc:28706];gene_id=ENSG00000187634;logic_name=ensembl_havana_gene;version=6 1 ensembl_havana transcript 918 19755 . + . ID=transcript:ENST00000342066;Parent=gene:ENSG00000187634;Name=SAMD11-010;biotype=protein_coding;ccdsid=CCDS2.2;havana_transcript=OTTHUMT00000276866;havana_version=2;tag=basic;transcript_id=ENST00000342066;version=3 1 ensembl_havana exon 5335 5516 . + . Parent=transcript:ENST00000342066;Name=ENSE00002727207;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00002727207;rank=3;version=1 1 ensembl_havana CDS 5335 5516 . + 0 ID=CDS:ENSP00000342313;Parent=transcript:ENST00000342066;protein_id=ENSP00000342313 1 ensembl_havana exon 6219 6269 . + . Parent=transcript:ENST00000342066;Name=ENSE00002696520;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00002696520;rank=4;version=1 1 ensembl_havana CDS 6219 6269 . + 1 ID=CDS:ENSP00000342313;Parent=transcript:ENST00000342066;protein_id=ENSP00000342313 1 ensembl_havana exon 10952 11076 . + . Parent=transcript:ENST00000342066;Name=ENSE00002703998;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002703998;rank=5;version=1 1 ensembl_havana CDS 10952 11076 . + 1 ID=CDS:ENSP00000342313;Parent=transcript:ENST00000342066;protein_id=ENSP00000342313 1 ensembl_havana exon 14220 14309 . + . Parent=transcript:ENST00000342066;Name=ENSE00002686739;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002686739;rank=6;version=1 1 ensembl_havana CDS 14220 14309 . + 2 ID=CDS:ENSP00000342313;Parent=transcript:ENST00000342066;protein_id=ENSP00000342313 1 ensembl_havana exon 14455 14640 . + . Parent=transcript:ENST00000342066;Name=ENSE00002715021;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002715021;rank=7;version=1 1 ensembl_havana CDS 14455 14640 . + 2 ID=CDS:ENSP00000342313;Parent=transcript:ENST00000342066;protein_id=ENSP00000342313 1 ensembl_havana transcript 14455 19439 . + . ID=transcript:ENST00000455979;Parent=gene:ENSG00000187634;Name=SAMD11-004;biotype=protein_coding;havana_transcript=OTTHUMT00000097863;havana_version=4;transcript_id=ENST00000455979;version=1 1 havana exon 14455 14640 . + . Parent=transcript:ENST00000455979;Name=ENSE00002715021;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002715021;rank=1;version=1 1 havana CDS 14455 14640 . + 2 ID=CDS:ENSP00000412228;Parent=transcript:ENST00000455979;protein_id=ENSP00000412228 bcftools-1.21/test/csq/ENST00000420190/abort-in-csq-push.txt000066400000000000000000000003321467060157400226530ustar00rootroot000000000000005500 C T . missense|SAMD11|ENST00000342066|protein_coding|+|56R>56C|5500C>T 14483 G A . synonymous|SAMD11|ENST00000455979|protein_coding|+|9G|14483G>A,synonymous|SAMD11|ENST00000342066|protein_coding|+|159G|14483G>A bcftools-1.21/test/csq/ENST00000420190/abort-in-csq-push.vcf000066400000000000000000000012451467060157400226160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 1 5500 . C T . . EXP=missense|SAMD11|ENST00000342066|protein_coding|+|56R>56C|5500C>T GT 0|1 1 14483 . G A . . EXP=synonymous|SAMD11|ENST00000455979|protein_coding|+|9G|14483G>A,synonymous|SAMD11|ENST00000342066|protein_coding|+|159G|14483G>A GT 0|1 bcftools-1.21/test/csq/ENST00000420670/000077500000000000000000000000001467060157400166435ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000420670/ENST00000420670.fa000066400000000000000000004206611467060157400210000ustar00rootroot00000000000000>9 9:91975682-92113065 GCCAAGTACAGTCATTTAACTGAACAATGTACAACTCTATTTTTATTTTTTCCAGCAGAG CAAAGAAAGACTCAGAAATTCATCCTCATAACTCCATTTCCCAGTAGAACACTCCACATT ACGAAAACTTCAAGTATGTAATTATTTTGTTAAGTGTGAAAGTGCTTGAAATCCAGACTT CAGGAGAAGAGACAGAAAACAGCACCAAGAATATAAGCCTAAAGCCCATAGCATTTCACT CATCAGTTTGTAGTGGTTGAAGCCACACCCAAAGCAAGAACCACAGTGAGCTGATGGATA TTTTACAGGAAAACTTCAGGTTATGAGTATGTGATGGTTCCGTGAGCAAGACTGGCATCC TTGGCTGGATGGGCAAGCACACACCTCACAGGCAGCTGGGCCTCTCGACTTGGGGTGCGG AGGGGGAACGTGTGGAGACAACCAGGGTGTCTCCAGCATCTTCAGGACACCTGTTGTGAT GGATCCTGAAGGAATTAGCAGGCGATGTATGCTGATCCCACACAAAGGCTGGTAGAGAAT TTGTCCAGCTCCAGAAAGAGGGGATGCAAAACAGGTCATTGTCACACTGCTGGGAAGACA CTCAGTATTTGCTAGGATCACCAGAGGGGTGCGGCTTGACTTTTAACAGAGGCTTTGGTT TTATGATAGACATGAAAACTGTCATTCAACAGACAAGAAGAGACGTGTGTGTAAGATTAA AGGCTGAGTAGCTTTAGGACAAGTTCACACACACAGTGACACAGTCTTCAGAGATACAGC TTTAATAATTAGAGACTTGAAAGCAGGTAGAACAAAACACTCATGAGACTCATTCCATCG TCAAGAAATTTAATATGGCACCAGGAGATTTGCATAATTGACCTATTTGGCTTTCTGCAT CAAGTTTGGTGTCCTGTTGCAGAAGCTGAGCATTGACGGGACAGAGGCATAAACTGCAGC GCTTGATAAAATAGAGCCCAGTATTCTGAGGTTAGTGAAGAAAACACAAAGACTTGACAG ATGCACTCCCAGATCGCATCTCACAGTCATTCAAGGTTTAGGGCAAGGCATTTCCATGTG GAGTCTCACCTTTTCTTGTCCCAGTCATGCATCTTGGAGTTCCTTGGCTAAGTCTGCAGG GAGGAGAAGCAGCAGGCTTGATTTGCATCAATAAAAGCAGCGATCTGTGCTGGCCATGCT AACCCTGTTGGCTATTAGGGGGTGGGGGCACTCTGTCAAGGGGAGTCACTGGGACGGTGT AGGATCAGCCTTCAGAGCCTGCTGCCTGACCGTAGAGGAGGAACCTGCACACACCCTGCT GTTTTAGTTCACGAGCAGCTATCAAAGCCTGTTAGCCATCCTGGTTACCTGCTTGTGCCA GACAGAACTTACTGTCCCAGGTAAGCACCTAATTTTTTAAGTCTTAGTTCCTGTCACAGG CCCACTTGGGTTCCAGGCTTCTCCACTGTCCCGCCTCTGCCCATCAGGTGGTGGCCCAAT GGCTGTGTTCAGAGCAGGCTTGGGCAAGACAGTTCACAGTTGTGGGGGACCAGGCCTTCT CCGGGGGTGGCTGTGGTCAGTGGCAGCAGGGTCTTGTTGGGGTTGAGGTCGGTGTCAGGG ACTCCTTCCTGGTGGCTACAGGGTGTCCTTGCTACAGCTTTCCTGAAAGAACAATGTGGT CTTTGAATCCTTGGTGGAACGGATGGGCCTTTCCTGCTCTGCAGCCCAGTCTGTCTCATA GCCCATCCCAGGCAGAGCACTCAAGGCCTCAGCCCCCTGTTGTGGTTCCCCTCCTTGGAG TCTAAAGATCCAAATGCCAGGAGTGGTTCTCCCATATGTGACAGGAAGGCAGAGCAGCAG CGCATTCACTCCACTCCCAGATTGTGCTGAGAGGCAGGAGGGCTGGAGAGAGGGAGCCTG TGTGTGCTGAAGTACAGAGGATCAGCTGTAAATGCCCAGCCTTTGGTGGCAACAGTTCGG GGGTGTACTGCTGGCAGCCACGTAACCCACACACTTTAATGCACTCATTTGAGTGCTGCA GACCCCACCGCAGGTGGTAGCACACAGTGATGAATCCCTGCCTTTGCCTTCTGTATCGGC TATTTAGGAGCCGGGGCTGGACAACTTTGTCTCCGTGGGGAGACAGGGAGCCTCTAGGGA GCCTCTGCCCCACTGCCTGCAGCTTCCATGCTGTAGCCCAGTTCCTGCCAGGGCTTAGCT CAGGAAGCCACTCCCCCTGACCCCTCCAACAGGTGCCTCAGGTGAGGCATCCAGCCAGGA GCTACCTGGAGGGTTCCCCATCTGTCCAGGTTTCCTGCCCTCCTCAAAGGAGTGGCTGGC TGAGTGCTCTGTACAGAGAATGGGGTGGTCGTGGGGGCCCATCTAACTAGACAGCCCCAC CTGTGAGTCCCTCCCAGTCTCGCCTCCCTTCAGTCTCTTTTAAGGGCTGGGGCCAGATGC CCCTTGATCTCCTGCAGTCTCAGCAACAAGACGTGGGATTTCCCCCCCCAGTGTTGCAGA TTTCATAAAGGAAACTGCTCCGGGGCTAAGAGGGAACAAGTGGGGTCCATGCTGAATGGG GCCCTTGAAAGATCCACTGGATGTGGCAGGTGCCCTGCCCCTGGCTCCAGCCCTCCTTTC TTTGCCCGGCTGCGGCCACTTACCCACGCCTTCCTCCAGCTCTGCATCATCCGGTCGTGC TCCCCAGCCACAGCCCTCCAGGCAGAGAGCTCTCTGGTCCACCTCTCCTGGTGGGTCACT TCTGGAAAACAAGCAGGGTCCCCAGGTCAAAGCTCTGTGGGCCTTTATGGCACCCTTGAT GCCCACTGGCCACCTTTCTCAATGGAAAGCCAATAAAACCCAAACCCAGAATGCCACCGT GCAAGCATGCTTTCCAGCTGTTTTTTTCACTGCCATTGTAAATAGTGAAAAATTACCTCA TAAAAGGGTAACAGTGGGCATGGGAATCACTTACCAGGTCTCATCACAGCAACCTGCACC TTCGAAGTCTTGTTCCCTGCTGAGGAGAGGACAGAGCAGCGATACTCAGCGCTTTCCCTG ATGGCGTCCTGCAGCCAGCTGAGTGCATGGGCCCTGCCATCGGGCAGTGCATGGGTCTGC ACAGGGACACAGGTCTCCAGAGCTCGCCCATTCTTCTCCCAGACAAAGCGAATGTCTGCA GGACCTGGGGACACAGACCGTTTCCACCTCTGAGTCCACATTTAGGACCCAAAGAAGCTG CCCCATGAGGGTGCAGGGGGGTTACCTCTGCTGTCCCAGTTGGACCTGAAGTGACTTGGG ACAACTTCCAATTCAGTCCCTGGGACTGCCCTGGAGGTGGCTTCCCCATGGCCAGCGGGA GCCTTGGCCTTGGCCCGTCCTGTGGACTTCCTGCTCTTTGACCTTAATTGCCATTTTTCA AAGCACACCTGTGTGGCCTGTGTCCCCTAGGACCCCCTTTCTTGCAGCGCTGTGCTGGTT TCTTACAGAATGGTTCTGGGCCTTGGAACAGCATCCCACCCCACCATGGCCCTGCTGCCA CACACATGTCCTGTGACCACATGGACAGAGACATCCCAAGGCTCTGCCATCACCAGGGCC ACAGCATGGAGAGGCCCAGAGCTCGGCCAGCTGTGTGCAGAGGGGGCTGGGCCAGAGTGG GGACCATGAGGGCCTGTCTCTCCAATTGAGACACTGGGGTGGGCTTGGAGGGGAGTAGAT GCCACAGGCTGGAGAGCTCAGACCCTGGCAGGGGCCAGGCCCTGCAGAATTACACTAGGA CTGCCGAGTGCAGCACATCCAGGATGGGCTTCCAGCCTTGAGCATGGACTCTGGGCCCGA CATTGGCCACTTCTGCCGCAAACCTCTGTTGTTTTTCTCTGGGCTTTTGATCTTAATTAC TTATTGAAGAAAGTAGAGAGGCCAGTTACTTCACACACACTCAGACCATCTGTTGCAACC TGCCAGGGTGGAGCCTGGCTGGCCTCAGCTTGTCTGATGGAGAGATCAGGAGGGTGGGCG AGGCAGAGACGTTCCCCTGTGGCCCAGGCTGCCTCGCCTGGGGAGGCCAGCCTCATCCCA GGGCAAGAAGTCTGCGCGGCCAACCCTGAGGGCTACTCCTAGACACTATTTGTTCCAGGT GGCTGGGGTGGGGCTGTGAAAACCAGAATGTTGGGGGTTTTGGGCGGGGGGGAGGGGCAC AAGTAAGTTCTGGTCAGCAGGTCACCTCCCGGCCTTCCTTGCTCGTGAAGTCTGTTGGCC CTCCAGGGGCTGCTGGCCATGTTGGGACAGGCTCAACTCCCTGTTCTTACTGAAGGAAAA ACAAGCACATCCATTTTGATCTGCTTCGCACACTGGCTTCCACTCAAATGCAGAAAGGGC TGAGGGGGGCCACAGTCCCACTAAGCTCCAGCCCCAGAGCGTACAGACCCTGGAGTTGAG CTGGGAGGGCCAGGCCAGGCCCTGGAGGGCAGGTGAGGGGGTGCAGGTGCTCCTTCTGTC TCTGAAGCTCCTGCTTGTGGTGGGGCTGGGGAGGCCGGCCAGCCTACTCTGCTGCTTCTG TCTCCCTCAGGCACAGCCTGCATCAGGCCAGGCACCCCAGCAGCGTGGACTGGGGTGACA CCCACCTGCTGCCTAGCGACCCGGCTCCCTGACCAGCACCTGCCCTTCCTCGAGGCCCAC CAAGGCCCCCAAATGGGCCATGGGCCACCTAGACCAGTGCCGGCCATGGCCTCTGCTTGA CCATGACACCTCGTAAGAATTGGTCTTTAGAAGTTAGATTTGCCCTAGATGTCCATCAAC CTCACAATGACAAAATGAAGTGTGGCTTCATGGAGAATGCTTAGTAGTGAAAAGGAAGGA GTTCAGAACACTGAGCAGGTAAAACAAATTCCAGAGCCAAAAGAGTCCAAAGTACCTGCA CACACAAAAACTGGCCTTGTTCTCAGGTGTAGGGGCAGAGGTGCATCCAGTTACAGGTAT TAAATGGTGTGGGTGGACCCACGCTCCCCTCCCTGGGCAGGACAGTAGTGGCCAGAGAGC TTTCCATTTCTGTGGCACATGCTGGACTTTTGAAAAGAAGAGATCGCCAGTTTAATGAAG CTGACTTTAGTAATGCATTTTCCCTGCTTTACTGACTGTGGCATCTGCTCATCTTTGTCC GGTCTCTTGGTCAACAATTCCCCACTGTCCAGGATCACCAGAGAATGCTCCTCCCAAGGA CTTGACCAAGCTCAGACCCTTTAGCTGGGCAGTCCTAGGAATGAGTCCCGAGGCAAGGAT GGGCCCAGTGAAGCCCTGTTTCTATCAGTGAGGAGTTGGGAAATGTCCAAGAAGGGGGCC ACAAGTCACTCATTCGAAGTGCCATCGAAGAATATTCAGCAACACAGAAAAATAAGTGAA ACAATATCTAGGAATGTGTGCATATATGTACACACCCATGTATACATGTGTGAACGTAGA TAGTCATGGCCCAAAAATGGCTGGGATGCTGGTGGTAACTACCTCTGGATGGTTAAATTT GGGATTGTTTAAATTTTTTCTTTATACTTCCCTGGAGTTTCCAAACTTATAACAAACAAG CATTGCTTTTATAATAATAATTTTTTATAAAAGTGTTACTTTGAAGGAAACATTCTGTAA ACTCAAGGAAATTCAGAAGGTGCTCCAAAACTGTTTTGCCTGGCGGCCCATCTGGCCCTG GCCTGGTGGACAAGCCCTTGTGAACAGGTTTGGTTTTTGTGCAGAATTTAAAAAAAAACA AAACTTAACACTCTATAATTTGTTTTTTCCCACTCAAAATGTTTTGGACTCTGGCCACAG ATAATTCCATGTATCTATCTACAAATATAAGTACATATTACATAGATGTACAAACATATG TCTCTATGTACATCTAGGTGCCCATCAACTGGGGAATAGATATTCCCTTTCCCAGCTGAT GGGCATCCAGGTAAAATCTCATTTTAAGAAACAGATTTTTTTGAGCTGTTATGATCAAGT AACACTTTTCTTTGAACAGACAGTGAAGTGAGTTCTATAAAAGCCCGGTCTCCTCCCTCA TGTGACCTGCACCAAGAACCACCCAGGGGACTGGAGTCACTGAGTCACAGGAGCCTCTGG AAGGTTCTCATGACCAAGCCCTTGAGACTAAGAATCTGGGTGGCCTAAGCTGGATTGGAT TAATCACCCAACGCCCCATCATGGGACCACTGACTGCAAAACCCTCAAAGCTCTACACTC TTGGGGTGTGAGCAGAAACAGACACGTGCTTACCACTGCTAACAGGCATCAGTAAATACT ATTTAAATACATGCTTGATCATCATAAGACATTAAAGATGTTAAAGAAGTACTTACGTTC CATGTATTCGTTTTTAAACTATCCATCTCTTTCTGAATGCATGAGAGAGAGGGAAAGTGA GAGTTACCATCAGTGTGCAGGGCCACCCCATCAGCACCGCACCCTCAGCGGGACAGGGCA GCAGGTGCAAACCCACGTATGTCCCACGGAGGACTGCTGGGGAGCTCCTGGAATCCTAGG CCCCCAGTGGGGAGCTGTCTTCCATCTCCCAGCAGGGCCTCCTGAAAACACCACTGTTTT CTTGCTTGGGCCAGTGCTCCAAGCTCCCTAACCATCCAACCCTGTTACCTCAAGAGAGCG GCCAGGCTGGGGTGCTACTCCCAGATCACCCCCTTGGCCTCTGTGGGGTGGGGACAAGAG GCTGGTCTGATGCTGTGGGGCTCAGCAGCCACCAACCTGGATGTGCCTTGGCTCTTCCCA GTGGCGAGCCAGGTGACACTGGTCGCGCCCTCAAAGAAGGGAAGTTGTTGTGGCTTACAA GGATCTAGGGTAGAGGTCCTGAGGACAGATATTTCCCCCTGGCCCTTCCTGTCACTGCAA CTAGCTTAAGTTGAAGGCAAATTAACTGCTGTGGCAGATGCCGTAGGTAATGATCTTTCT CCTACAGCTAGGACTGTCGTGAGAAGACTGATCACCTTGGTATAAGCAAGGGCCAGGTTT ATTCACCAGGGCTGGGTTTATTACATCAACTCAGGAGTCTGGGGAGGCTGTTGGCAGCCT GGGCTCCAGCACTCAGCCTGTCACTGGGGCACCTCCCACCTGCTCACTCCCACCCCAAGC CTCTAACGGAGCCAGCTGGTGCCAGGACCACCATGGCTTCAGAGCTTCGTGGATGTGATT ACAAAATATGGAGCTGATTCTACTCTGCGACAAACCAGGTGCCCTCTGGGCAGTGGCCTC GCCCTGAGGAAGGCCTGGAGGGGTGGTGAGACATCCACCCAGTGACTGAGTTGCTCGGGC CCATCCTGGAAAGTGCCCCCACTGCCATCTCCTGCAGCACTCCTCTGTGTCCTCCCGGCA TCCCCATGCATGTGGCCCACTCTGACCTCAGGGCTGGCTGCCTCGGGGCCAGCCCATCTC CCAAACTCACATCCAGGTGGCCTTCCTGCAACTAATGGGGCAGCGGGCACATCCCCAGAG GGGCCATTCTCTGCACACAGTGCTGGCCGCTGGCCATCATGTCTTCCATGATGGGACTCC TGGCTTGTCCCTGCCTGTACCCGCTGCCCGGGCCTCACCCGGACACCTGCTCCCAGCCTC TTTTCCCGAGGATCCCACTGCTTCCCTGGCCCATCTCTGTGCTCTCTCCTTGGGGCACGG TCTTTTCTAATCCTGGCCATGGCCCCTCCTCCCTCCCAGACTCTGGGGACCCTTCTGGGG ACAAGGACAGTGCAGCTGGGGGTATGCCCTGAGGCCTTGTTGGTCATCCTTTCTGTCCTC TGTTGAAGTCACAGAGTAGCCAGGGGCCCCAAGAGGAGGGAGGAGAGAGTGAGACCCCTG CCACATAGGTAGCAATTCTGACAGCTCCCTTCTCTGAGTCCTCATCTCCCTGACAGTCAC CAGGCCGACGCAGCCTAACGTTTCACTCTGGTATGCTCTAGACCACTCAGGGCACTGGAC CAGCCCCAGCGCTTCTGGAATGCACCTGTTCATGCCTGCCACTTACTGGCCAAGCCGCCT TATCAATGTGGGCAGGAATCCTGAACCTCTTCTCTGCAAAGGGACCTGAGAAAGTACCAC TGAGGCATCTGTAGGCATCGCCTGGCTCCATGGGGGGCCTGTGGGAAGGCACCACTGAGG CACCGAGGGCATTTCCAGACCCCAGGTAACCAGACAGCTGTGTTGTAAAGGCACGTGGAA TTATCCCAGATAACAGAAGAGACATGGATAGTTTCTGGTGAAGCTGCCTCATCTAACATG CGAAGGACCTCAGAGCACAGGGAGTTGATAGCACCACCTTGTCCTGTCCAGCAAGGGTGG CCCAACACACAAGGTCAACTAATTCCCACGACGGCCGTGGCCTTTCAAGAGTCTGAAACA AAGGGAAATGTCACAGAGCAGCTGGAACACACACATGCGTGCCAACAGGCCACTGTGGCT GCTAGGAACGGGGGCCCTCTCCAGAGCCCTGGGCCCCTCAAAGAGGACCAAGGGCGCCTT CTGCTGCTGCCCTCTGATCCCAGTGGTTCCAAGGGCTCTGATTTCTAACACTGTAGTTAA AACATAAAAGGCCATCCCAAATCCAAATATCTAAATGCTGCCTAAAGTATGGGGGAACCA TTATTAGCTTTGAAAATGACACGGGTCTAAACTTGACATGGAAGATAGTCCTGGCAGAGG TGAAGGCAGGGCCCTGACAGGGTAAAGACTGCACTTTGGTTAAAAAATTATATCGATCTG TTTCTGTGTGTGCACACTAATGTACAAGTGCATGATTTGTATCTGCATGTAGACACAACC CATCGCCATTCATCGCTATTGATCCTTACGTTTGTATGCCAGATGCGCTATGTGCTGGCA CACGGGTGGTGGGGTTATTTTTTCACCCATCTGTATTCTGAGTGATCCATGAGGAACTTG GGTTCATCAGTTCAGACGAGCAGAGCTCGGCTGCATGCTAACTTTACTTCACCAGCTCCA GACGGCTTTCCTCCCCTTGTCAATACACATGCTGCTCCACTTGCCACGGGGCTGCATCCC AATAAACCCACTGTGAGTTGAAACGATCCTAAGTCAACAATGTGTGTGTGTGTGTGTATG GTTGTGTATGTGTGGATGTGATTGGTGTGGTGTGGGTAGCGTGCATGTGTCTATGTGGTG TGTATGTGCTTTGGTGTGTGCAGTATGTGTGGTGGTGTGTGTGTAACAGTGGTATGATTG GTGTGTGTGTGATGTGTGTTGTATGCTGTGCTGTGTGTGGTGCATGTGTGAGTGGTTGTG TTTGGTATGGTGTGTATGGGGGTGGTTTTAGGTGTGTGTACAGTGTGTGTGTGTGGTGTG TGTTGGTATGTGTGCACATGTGCAGTGAGTATGCATGGTCTGTGTGTATGGTGTTTGATG TGTGTGTGGTGTGTGTGATTTGGTGTATGTGATGTTTTGTGCTGTGCATTTATTGTGTGC ATGCACATGGTGTGTGTGTTGTGTGGTGGACATGATTGTGTTTGTGATGTGTGTGCGTGT TATGTCGTGTGTGTGTGTTGTGGTACATGTGTCGTGTGGTGTATATTGTGGTGTATCTGT ACGTATGTGGTGTATCTGATATATGCGTGGCGTGTGGTGTGTGTGGTGTGTTTGTGGTGT GTGGCTGGTGTGTGGTGTGTGGTATGTAGGTGTGTGTCTGGTTTGTGTGTGTGGTGTGTA TGAAGGAGGTATGGTGTGTGTGTGATGCTGGCATGTGGTGTGTGTGGCATGTGGTGTGAG GGGGTGTGGTGCTGGTGTGTGGTATGTCTGCTGTGTGGTCTGTGTAGTGTGTGTGGTATG TGTGTCTGGGATGTGTGTGGGGGGGTACAGTGCATGGCATGTGTGCGGTATACGTCATGC TCATGTGTGGTGTGTGTGTCTGGTGTGTGGTATGTGGCTAGCATAGTCTATGTAGTTTGT GGGGTGTGGTGTGTGTGTGGGGTGTGGTTGTGAGGGGTGTGATGTGTGTGTGGGGTGGGG TGTATGTGTGGGGTGTGGCATGTGTGTGGGTGTGGTGTGTGTCTGGGGTGCGGTGTGTCG GGCGTGTGTGTGTGGGATGTGGCGTGTGGGGTGTGTGTCTGGGATGTGTGGCATGTGACT GGGATGGTGTGTGTTGGGGGGGTGTTGTGTGTCTGGGGTATGGTGTGTATCTGGGGTAGG GTGTGTATCTGGGGTGAGCTGTGTCAGGGGTATGTCGGGGTGTGGGGTGTGTGGTATCTG GGGTGGGGTGTGGTGTGTGTCAGGGGTATGTGTATGTCTGGGGTGTGGGGTGTGTGTTAT GTCTGGGGTGTATAAGGTGTGTGTGGGGGGGTGTGGTGTGTATGTCTGGGGTGTGGGGTG TGTGTTATGTCTGGGGTGTATAAGGTGTGTGTGGGGGGGGTGTGGTGTGTATCTGGGGTG TGGTGTGTGGGGTGTGGTGTGTGTCTGGGGTAGGGTGCGTATGTGGGGTGGGCTGTGGCA TGTGTGTGGGGTGTGGTGTGTGACGGTGTGTGTGTCTGGGGTGTGGTGTGTGTGGGGTTG GTGTGTGTCTGGAGTGTGGTGTGTGTTGGGGTGTGTGTGTCTGGGGTGTGGCATGTGTGT CTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGTGTGTGGGGTGTGG TGTGTGTCTGGGGTGTGTGTGTGGGGTGTGATGTGTGTGGGATGTGTCTGGGGTGTAGTG TGTGTGTGTCTGGGGTGTGGTGTGTGTGTGGGGGTGTGTTTGGGGTGTGGTGTGTGGGGG GGGGTGTGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTCGGGTGTGTGTGT GGGGTGTGATGTGTGTGGGATGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGTGTGTGG GGTGTGATGTGTGTGGGATGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTC GGGTGTGGTGTGTGTGTGGGGGGTGTGGTGTGTGTCGGGGTGTGTTTGGGGTGTGTGTGT GGGGGGTGTGTGTGTCTGGGGTGTGGTGTGTGTTGGGGGTGTGGTGTCTGAGGTGTGTGT GGGGGGGTGTGATGTGTGTGGTGTCTGGGGTGTGGTATGTGTGTGGTGTGTGGGGTGTGG TGTGTGTGGGGTGTGGTGTGTGTGGGGTGTGGTGTGTGTGGGGTGTGGTGTGTGTCTGGG GTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTTGGGGTGTGTG TGTCGGGTGTGGTGTGTTGGGGGCGTGGTGTGTGTCGGGTGTGTGTGTGGGGGGTGTGAT GGGTGTGGTGTGTGGGGTGTGTGTGTTGGGGGGCGTGGTGTGTGTCGGGTGTGTGTGTGG GGGGTGTGATGGGTGTGGTGTGTGTGGGGGGTGTGGTGTGTGTCTGGGGGGTGTGGTGTG TGTCTGGGGTGTGGTGTGTCTGGGCTGTGGTGGGTGTGTGGGGTGTGGTGTGTGTCGGGG GTGTGTATGGGGTGTGGTGTGGGTCGGGGGTGTGGTGTCTGAGGTGTGTGTGGGGGGGTG TGGTGTGGTGTGTGTCTGGGATGTGGTGTCTGGGGTGTGGTGTGTCGGGGGTGTGTGTGT GTCTGGGGTGTGGTGTGTGTGTCCCTGCCCGTCCTTCACGGCTGGTACCAGGGTGACTGA CTATAGTAAATGTGCATTGCTAGCCGCATGACAAAGCTTAGACAGCAGTCCATCCCAGGG CCAACGCGGTGCAGGATGGCTGTGCAACAGCTCTGAACACTCTCAAGGCCGCTGTCCCTC CTGTGCGGCCACAGTGCACACTGAGGCAGTCGGCCACTCCCAGCTGCTCCAGGCCCTGCC GATGCACTCAGTCCCCCAGGACTCAGGATCATAGGGCTAGCGGCTCCCAGGGCACGGGCC CCAAGGCAGTGCAGTCCTGACCTGCCCACCCCTCTTGTCACTGAGCCCAGGGTACCATGC TTGGGGTGACACCATGTGCTGTCTCACCTGGGCACTGCAAAGGCATAGTTCCCACTATGA CACCCCTAGGGTGTCCCAGGGCCTTCTCAGGACCGTCCCATCCTGCCCCAGGGACAAGGC TGGCCTGTGCCAGGGCCATCAGTGGATCTTTCCGTATCATCTTCCACTGATAATTCCACT TCCTAGAGGCGAGAACTGTGGTGGAGAAGGGATGAAATGTGTCTAGGTGGAGAGTGGCAC TGGTGGCCAATCTCCCACCCCAGCTCCTGACACAGGCCCACAGGTGTGGCCCTGTCCCTC CCTTGGATGGGCACTGAGGCCCCTGGGTGCAGGACAAGGGTGGGCCTCCACCCCACCACC AGGCCTCAAGCTCTCGCATCCCCAGGACACAGGCCTCTCCGCCCTACTCCGCCCACGTGG CCACATCACCTCCACCGCACCCCACGTTGGGCCCTTGTGCCCTGGCAGCCTCTGCACACA CCACAGGCTATGTTTTCCCCTGTGCAGACCCACCCCGATCCCCTTTCAGGAAGCGCTTTG GCCTCAGAGGGCCCTCACCTCTCCTGGATGGCCAAGTCCCTGGGGCCACTTTCTGAGCAC TGGCCAAGTGTTGGGGCAGGTGGGGACATCTCCTGGGTGACACATGGGCCTCCACCAGCT CTGGGGCAGACCCAGTCCCCAAGTGCAACCCTGACCAGCTGACCTTCCATCAGTCAGCCC TCTCTGGGGGGTGAGACGCTCCCCAAGACACAGGGTCACCCAGCAGAGCTACAGGCACCA GGACGCAGCATGGGGAACTGAAGATGCCACGAATGTCCTCTTAAGTTTCATATTCTAAAG ACACTTTGCTAGCCCTTTAATCAGACAGCCCCCAAACCACTGTGACAGCTACCACGAAAA CAGCCATTATAGCAAAGAAAAACCCAGCCAAGTTCCAAAGCAGCCCTGCCCTGGGTGGCT GGGGGAGGACACAGGCAGAAGCGGTAGGCCTGTGCCTTGAGTGCACTGTATTGCAATCTC CAGGCTCTGGGCCTCACCTGGAATGGCTCATTCCTGGCCCACAAGGCAGAAAATGGCACT CACTCTCCTCAGGAAAGTCTCTGGGACTTGCAAGTCACACTGTGGCCTCTGTCGCAGGAA GCATCTACAGACCCCAACAGAACCCTGGAGCCTACTCGGGAAATTCACAGCCACAGCCCC TCTGAGTTCACGGCATGCCCATGATGCCCTGGCCTCGGCCCACCCTTGAAAAGGCTGAAG CCACTCTCTCCTAAGCTGGTGCTCCCTGGGGAGGTCTCACAGCCTTCGCAGGCTGTGGCC TCAGTGGAACAAGTGAACGAGAATGTCCCAGATGGGGCCAAATGCCTCTGGAGAGAAAGT AAAGACCACGTGAAAAGGGGGTGGCGGAGGGCTGGGGGCCTCAGTTCTCAATCTGTTCAG TCCATCCTGAGCACTGGCAAAGGACTGCCCTCCTCCCTCAGCTCCCCTACCCTCTACACA CTACTCCTGGCCACACTGCTGCAAGCCCACAGCTACATTCCCCATATCCATCTGTGACCG CCAGCTTTCTGTTAGGTCTGGCCATGGGAGTCATTGACAGGAGACAGGAAGTTGGAAGGA AGAAACATTTTTGTGGCTTCAAGTAGGACCTCCAGCAGTGAAGGCAGTGTGGCGGGCAGG GAGAGGCTGCAGATCACACGGCCACAGCCTCGGTGGCACAGCAAGTGAGACTGAGTGTTT GACACTTCACTCTTCCTGCCCATGGCTGATAATGGAAACCTCACCTTCCCACTGTTCCCA GCCCTTCTATCACCTTTGTAACCAATTCCCTGTGTTAAATGCCCTGTGGTTGAAATATCT GGGGTGGTTTCTGTTGCTGTAACAGTGATGTCCCTTCTCCCTGGGCACCCATCTTTCATT CCCTGCTGACCCCAGGGGCTTGTGTGTATGCCTGCCTAGCTACAGGGGGTACACCTGGAG CCTCACATTTAAAAATGTAACAGCAGCCGGGCATGGTGGCTCATGCCTGTAATCCCAGCA CTTTGGGAGGCCAAGGCAGGTGGATCCCCTGAGGTCAGTAGTTTGAGACCAGCCTGGCCA AGATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGAGGTGTG CCTGTAATCCCAGCTACTAGGGGGGCTGATGCAGGAGGATCGCTTGATCCTGGGAGGCGA AGCTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTC TGCCTCAAAAATAAATAAATAAATAACCAACCAACATTGCCTGACCATACAGCCTGCCTG CATCTGCCCGCAAAGGAGCCCTGGGTCCACGGCCAGTTCATAGAGACCCGCCCGCTTCCC AGCCTCCCCACCGAGGAGGAGCTTCCTGAGTCTGCCTGAAGGACCCCAGTGCTGCGACAG GACACAGTCTCCATGGAGACATGAAGTCCTCTGGGATGCCTGCACCAAGGCAAACTAGCT GGCCGAGGAGCACCATTCAGCTGTGAGAGCGGCCACAGGGGGCTCAGCACAGCCTTGGTC CGTAGCACCCAGTGGAGGGCAGGAACCACACAAGCCAGCCTAGCAAAGCTCCGTCTCCAC AGTGCTCCATGCTCACCGGCAGCTTCTCCTGTCCAGTGCTGGCTGCCAAGGGACATTCTG GCCTCAGCAGACATGGGCCACCTGGGGCTCTCAGAGCTTGTTTAACAGGAGAGGGCAGCA CCTTAAAACTCTCAGGAGCTACTGACAGTGTGTTTAACATGTTTAAAAAGAGAGCAATTG GGTTTGCTTTTCCTCTTCATTAACTTCATCCCTCCCCCGGGGCAGGCTCTAACAGGCCAC TTCCTTTCTTTCTGTATCTACTGATCAGTCAGATGACAACACAGGGGCCACCAGGGCTAC CACGCACTGCCTGAAGCACAGGATACATCTTTGAAGTGTGGTTCTGGACATCTACTATCT TTCAAGAGCAGATATCCCATCCGAGTATTTTCCAATCCAGGGCAAATGCCTCCAGGTCCC AGAGGAGTACACTAGACTCTCAATCTTTTCTGTTTTTATAATGATGATGATTTTTGAGAC AGGGTCTTGTTCTGTGATCTAGGCTGGAGTGCAGTGGCACCATCATACCTTACTGTAACC TCAAACTCCTGGGCTCAAACAATCCTCAAGGCACGTGCCACCAAGCCTGGTTAGTTTTTT TCACATTTTTGGGTAGAGATCAGGTCTCGCTATGTTGCTCAAGCTGCTGTGAAACTCCTG GCTTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGCAGGGGGATTATGCCCGCCAATCTT TTCCGCTTTTAAATACCACGAAGCAAGTCATTAAAACAACTCCCATTCTGGAAGCTCTTA ATTTTTTAAAATTTCCAAATACCACGTATATCAACCTCCAAATTGTTAGCAGAAATAGAA GCACTCTGGCTCTGGAGGCTGAGGCAGGAGGATGGCTTAAGCCCAGGAGGCAGGGGCTGC AGTGAGCTATGATTGTGTCACTGCACTCCAGCCTTGGTGACAGAGGGAGACCCTGTCTCT TGAAATTTTTTTTTTTTTTAAGGGAGAAGCAATCCTATATACCACAGGTTGGGAAACTGG GGCCTTTGGGGCAAATCTGGCCCACCGTGCATTTTTATAAATAAAGTTTTACTGGCACAC AGCCCTGACCACTCGTTGTGTATTGACTATGGCTGGTTTTACAATACAACAGCAGAGCTT AGTGGCTGTGACACAGCCTGCAGCCCACAAGGCCTAAATATCTAGCCCTTTACAGAAAAC ACTGGTTGACCCCTGTACACTAGAAGTGGCTTCACACTGTCTACAGTTTCCCTCGGGATG GACCCACAATGAAAGCGTGAAACGGCTCAACCCGAGGGACGCAGCCAGGACAGATAAGGA AGGTAAAGGAACATGTGGAGGGATGTGGAGGATGCCCCCGCCCGCCCCCCACCTGTGGGA GGAGACAGATGGACAGGGCACAGGGGACAGAGAGGGCCCAACTCACCTGTGGCCTGGCAG AAGAGGTAGAAGTTCCCCAGGGCGTGCACGTGCTGTGCCTGGTCACTCAGGAAGGGCGGC AGCAAGGAGACCCTCGAGCTGCTGTCGGGCCCCGCACCCGAGGCTGGCCAGGGGGTCCAG GGAGAGGAAAGCCTCCTGTCCCCCACATGGCCCAGACAGGACAGGGAAGAGGAGCCAGGA GGAGGGAGGGGCTTAGGAGACGAGGCTGTGAGACAGAGAGGACAGAAAAGAGAGGGCACT GAGGAAGAAGTCGCCAGGAGCACGTCACAGGCCAGAGAGGGCAAAACACAGCAGGAAACG GACAGAAAAGAGCGAGCCCAGCTGTCCCGCCTGGGCCATGCAGGGGCGGGAGGCTGCACA GCCTCCGCTAAGGAATGTCTTCCCCAAATCAAGGATAGAAGCTTCTCATTTATTTGGGTA CTTTCCAAATGTATACAATTCAAAGTAGAAAAATAAAAACAAGGTAAATCTTATAAAACA CAAATGTTTACACCAAAATGGTCAAATCCTATCATGCTGGAAGATAAGACTGTCCACACA CGCGCACAAACATCCAGAGTTTATTGCTCTTCACCATGGAAAAAAAGTCTCTTCCCGATG GGTATTTACAAAGCGGGGAGATGGAGTGTGAAATTAACCAGTGTTGAAATCGTACCACCC ATTCACATCTTCAGGACAGTGGCAGGAACAGCGCCGTATGCTTGAGGGTGCTGTGGTCAC AGCTCGCGGCCCCGGCCACCGAGGCCCAGTTCCCTTCCAGTAGTGGGCAGCTCAGTGAGG CTGGATAGAAAGTCTGGGCAGGCAGTGGGTAAGCAATTGAAGCAAGAAGAGAAAGGAGAT GTTCAGAGAACCAAAGGCGCCCTTGTGAAGGTTCCATCTGTCTCACAGGAGGTTCTGACC GACAGCTGTGGGCTCCAGATTGTACCGCACTCCCATCTCAGCTCTGGGCCAGCCTGGCTC CACTCAGCTCATCCAGGCTACCTTCCCTTGCTCAAAACCCACCTCGTGGATGTGGGAAGG TCCTCTTCTTCGAGAGAGTAAAAGTTAAAAAAAAAGAAAAGTAAAACGAAGTACAGAAAG AAAATCTCTCCAAAAACAATGCTTCCCTCAAGGAATAAAGTTAAAAAAAAAAAAAGAAAA AGAAAAAAGGTGAGTGGGCTCCGGGGAGTGTTTATGTCTACATTTCTAAAAGCAGAAAGA ATGCATTTAGCAAAAGGAAGTTTATCCCTGAGAATCTTAAGCAACGTAAGCCGTATTTTA TGCCAAATATATAACAAAATCTGGAAGATATACATCTTCTTCTAAATATTAACACAACTG CTTCTGTAACTAAAAAAAAATGACCCATGACATAAACACAATCAAAGCAAAATCCTAAAA AAATAATTAAGTGGAAGAAAAGGTTCGTGCCAATCTGGACAACAGGCGATAAGTTACCAA TCTGATAAACTAAAATGTCATTTCCAATCTGGAATTAAATAATCTTTTAGTGGCTGCTAC GGGGAGGGGAAGCTGAAGGGATGCTCTTCTCAGCCAACAGAGGTCCAGCCACCTTTCCCC CACTACAGAAAGGGCTCAGGAACTCCGTGCCGCCCGTGGGCCTTCTTCAAGTACTCCGAC TGACTTCGGAACACAAGACTGGGATGCAATGCTTGTCATTTTTCCAAAAGGACAAAGAGA AACCAAGTCACAGGCTCAACCCAAGAGAAAATAGACAAGAGGACTGAGGTTGTCTGCACG ATGCGGGCTAACCTACGCAGCACTGCACGAGACTCGGATACTGAACAGGAGAAACACAAA ACTCTCCACGCCTGGACACGTCGCAGCCGAGGCACCAGCGGGGATGCACAGCCGGCCTCA GTCTCCATCTGCGTCTGAGTCAGCGAACTTCAGCTCACACTTGACGTCAAAGGGCTTGTC CCTGGCAGAAAGGTCGTCGATCCTCTGTGAGTCCTCCCTATCCGTGGGGACTTTGCTGGT GATGGTGTCTTGCTCGGTCTCATAGCCGGTGTCCAGGGCTGGCTTGGGGTGCTCCCCATT CTGCTGGGAGAAGCTCCCTGGCTCTACTAACGTCTCCTTCAGGCTCTGCTCACGGTCACA GAAATCTGACTTGGGCTTCTTCTTCCCAATTAGTAGGGCCGAGCGGAATTTCAAGCACTG TCTGGGCAGGTATCCCTTATAGCAGTTGTAGAAAAAGAGGCAGAGGAAGAGAACAAAGAA GAAGAGGAAGAGGGACATGAGGAGGCGGTTGTCGCTGGACTTAAGATACATGGTTTTCTC CGAGTGGAGCTGGGGGACCGTGTTGATGACGATCTTTGGTTCGCAGGATGTGCCGGTGGG CGCAGGCTTGGGAGGAAGGGTGATGGCCCCGGAGGAGGTGGCCTGCACGGCTGGGGTTGG GGGAGAAGACCCTTGGGTGGATGCCACCAACACTTTGGTGGCAATCCTACTACCTTCTGT CTGAACAACTGACAAGGTGGGGGCCACTACGGGCTTTGGAACCACCTTCACTTCCAGGAC GTGCTTGGCGACCACTTGGAAGACCGTTTTGTTCTTAACCCTCTCCTCTGACAGGCACTG GTACACCCCACTGTCTCCTTCTGACAAGTTGAAGATGAGCAAGTTTTTTCTGCCCATAAG ACCGTACTTGGGGCTCTCGGCCTTCAACACGCCATTCTGGAACTTCCAAAAGACCCGGGC CAGGTTGGATTTTTGGGAGCATTTCAGTTCCGCTGTGCCACCGTGCTTGAAAAAATGCTG CCGGTAACTTCCTTTACTTTTATCTGGAACATCAAAATAAACGTGCACAGCGTCAACAAT CCCCATTTGCTATTTAACAACTTCTTTAAAATACCCACAAGATGACGCAAGAGTTTCACC CACTGTAGCAACATGGAATCTTCCAGAACAACTAAGGAGATAAAGACATGCGTGACCAAA AAGCAAAGATGAGCCCTGGATGACAGCCCATGGGGACAAAGAAATTGGAGGCAGCTCTGA GCAGCAGAAATCCCATTTCTCACCCGTGTCCCAGAAGAAAACGCGTCAGGCTGGGGAAGC TGAGCAGAGGCCAGTTCTGTGCCTAGTGTCAGCTCTTTGAATCAGACACGAGACGCTTCT GCTAATGGCTGCAAGGAAGACTGGCCTTTCAGTGCATCTCAGCACTCTCCTCCTGCCTAA ACTTTTCTTTTTTTTCTTTTTTTTGAAACAGGGTCTGGCTCTGTTGCCCAGGCTGGAGTG CAGTGGTGCAATCACAGCTCACTGCAGCTTCAACCCCCCCAGCTCAAGGGATCTTCCCAC CTCAGTCTCCAGAGTAGCTGGGACTACAGGTGACCACCTCCAGGCCTGGCTAATTTTTGT ATTTTTTGTAGAGACAGGGTCTCACCACGTTGCCCAGGGTAGTCTCGAACTCCTGAGCTC AAGTGATCCTCTTGCCTCAGACTCCCAAAATGCTGGGATTACAGGCATGAGCCACTGTGC CCGGCCAGCTTTTGTTTTCTTTTTAGAGTCTGGGTCTCACTTTGTCACCCCAGGCTGGAG TGCAGTGGCATGATAAGCTCACTGAGCCTTGAACCCCTGGGCACAAGCAATCCTCCTGCC TCAGCCTCCCTAGTAGCTGGGACTACAGGCGTGTACCACCATGCCCAGCTGCCTAAACCT TTCTTAGTCTGATGACAGCTGTCTTGTCAGGGTCAGGAAGACACAGAACTGAGGGTCAAG TCTGCCTTTAGCACCCTGGAAGGTGGCTGCTGGGGAAGGGGCATCTGGCCTGATGCCACC CCTCCCTCTGGGTGTGGTGCTATTTCAGACATCCACAGGCGGGTGAATCCCAGGTGGGAG CCCCAGGGGAAACACCACCCCAGCCCTTACACTGCCTGAGGATTAATCACTCATGGGCTC CTTTCTCCCCATTTATAACAGGCTTAGGTTTTGCTTAATGAGCCCCAAGCTAAGCAGAAA GAAAACAGGATGGTTTTGGAAGGAGACTGCTTCCCAGTAAGCAGATACACTCTAAGTGGC TTCAAGTACTCTTTCGGCAAGAAAAAAAGACAGAGAAGACCACGAGTCTGCTACAGAACA CTTGACCTCTGTTCCGAGTGGAGAAAGAAAAACAAAACACACACAAATGCCACAGAACTG AAGCACCGTGAAATGGCTACAAGACCTCGCCACTCCCAAAGGAAATGGGACGTCGAGGAG TCACTCACCCGGGCACACAGAAGCATCGCCGCTCATCTCCTGAATCAAACCCCTGCAAAA CAACCGGCACGTGTTATTCACCCACACACATGGGGGACATCCCCAGGCAGCGCATCCCGC CCCATACCTGCTGGGGCTCTCGGTCTGGTGCAGAGCCACGCAGGTCGCTGTGGGCGGGCT CCAGGCGCAGTAGGGGTCCCGCGCCAGCACACAGTCCTCGCAGGTGCCGTGCTTCCCACA GAAGGCCAGCGGGGCCTGGACCACGCCCGAGTTAGAGCCAGCATAGACAAACCTGTTGCC CTGCGTGTATGAGACAGAGAAGAACTAGCATCAGGCAAGCAGGCATCCAGGAGCATGGCC TCTGCTTCTGCACCAGTGTGTGGGAAGCAGCCAGAGTGTACCTTCAGGGGACATTGCAGT AAGGAGGAGAGGTACTCAGAACCAGAGGCAAACAAGGCAGGTCTGTGACCTTCCTGCAGA ATCCACGTGCTATGTCAGGGCTCACTGGGCCTTAGGTCCAAATCCCTCTCTCCCCTGTCT GGGCACCCACAGGTGCCTGCCCTCCAGCAAAGCGCTTCTCTGCACGTGTTTCTCTTAGCC AGTGGGGAGGCTGTTCAGTCCCCACCTCCAGATCTCCTCCCTGCAGCAGAGGATGCATGA GCCTGGCACTCCCGGTCATCTTCCCGGCCTCACTATAGGTGAGAAGGGGCTGCAGCCAGA GGCTGAAGCACACCACCTCGAAGCCCAACCTCGTCCCCCGAGCCAGAATGTGAGCACCTG TGGGCGGGGAGCCTCTCGTGAGGGTCTGGATCCAGCAGAGGCCTAACATAACAGGGATGC CAAACGGACGACATGCAAAGGATGAGGAGATCGTGATACAAAACATAAAAAAGGAACAAT GCCTTTTGCTTTTCACTTATCTATATGTAAAAGGGAAGAGCTCACAGACGGGAAGTCAAC CTCCGAGCTCCAGAGCAGCCACACCCACAGCAGAGGGCAGGTGAGACTCTCCCACCTTCT GGGACACTTGGTTCCCAGTGACACCAGCTTCAGGTCCATCCCATCAGCCCACCTGGCACC AGCAGTGCCCAGCACACAGGCATCCAGGGCTGCTGACTGCTTTTGAACGGAACTCAGCTG GAAGGAGGGTGCCCCACATGCAGTGCACCCACCTGAAGCTCGGGGGCGTGCAACAGACCT GGAGGTGGCCCGTGGAGCGCGCTCTCTAGCCTCTGCCCAGGGCATCTGCCTCAACAGCCT GGGGACACCTTTTGGTTAACAATACAAGATTCCCAAATTTACACATGACTTAGTGGTTTA CAGTCAGATGAAACACGACCTTCATCCTCAGAGGATACGCTCGGAGTCAACTTCAGAGTG TGGTTGGAAGATCACAGGCCCTGATGCCAATACAGGAAGCCCCAGGCCACACATCCAGCT GTGCGGACACAGACCCACGAGAGAAAGGGAAAGCCCCCAAGGATGGAAACTGTGATAATA CACAGCAGAGGGAACCTGGCCCGCCGCTGGCCTCACAGCAGCAGCAGCAGCAGAGACCTG GGCAGATGAGGCCATGTGTGAGCCACGTTTGTGGGAAGGATTGAGGATGACATCCCAGAT CACAGTTCGGGCATCGCGCGGCTTGTGGAGGTGGCGGAAACATTCTCTGGCAGCAAAGCC AAGCTGGGTAACTTCCAAGGGACAGCTGGTCCTGTTGGGTCCCGCGGGGGGCACCTGCGA GGTGGCGTGAACACCATGCAGTGCAGAGCAGGGTGCCCTGGGTGGCCAAGTGGGGCCCGC CTGACTCCTCACCCCAAAGAGAGGCTTGAGGGTAGCTGTGGAGGGTGGGGTGGGCTCTGG GGGGCAAGGCCTGTCCCAAGGGGATCCAGACCACCTCCTGCACCCTGCGGGAGACTCAGC CCCAGCTTCCGCTTCTCCCGGATGGGGCTGGGCTGCAGCCCAAATGAAACTAAGCTGTAA AAACTAAACGACGCCACACAGAGACCAAGGGATGACTGTGGAAGGGAAGAGGGGACAGGG AAGGAGGAACTGGTCGTCAGGACAGCCAGCTGTAACTGCTGCAGGCAGGACCCACTGGTC GATGTGGATGTCAGTGGGTGGGAGAACAGGGCATTTCTGTAGCCTCCAAGTCTGTCCCTG CAAATAAGCATGAATGACTGTGGGGGTTTCCCACATGACTCCCCTGGGAGGTGGGGCTCA CTCTCCCCCACCCCCAGTGTGGACTACATGCCCCGACACACTCGACATGGAAAAAGACGG TGGTGACTTGGACAGAATGACCAAGGTCATCACGCTGGTGCGAGTCATACAGATGCCCCA TCCCCAGAAAGCGCCCTCTTTGGTGCTCCCCCTAAAACCACGACCCCAAGATAATCACAA GAATACACCAGACACACCACAAAACACCAGACTACTCCTCTCCAGGAGTGCTGAGGTCAG GGAGGCAGGAACAGAGCAGAAGCCGAGGAGATGCAGTGTCCAGTGCAACCTGAGGTGCTG AGCCAGGAATGTGGTGGGCGGGAGGTAGGAGGGTCCAGGGTCTGGGGTTCAGGTAACGCA CTGCACCATGACAGCACCTTGGCTCAGATAAATGCACACTGGCTATGTGAGACATCGGAC ATGTGGAGCTAGGTGGGGGCGCTCAAGATCCTTCTGTGCAATCATCAAAACTCTTCTGTA AATTTAAAATTATTTCAAGACAAAATTTTTAAAGGCAAAGAAAAAAAGCCTGACCAGGCA CCTGGCAGCATGAGTGAGGCCCGCTGAGAGCAAGCCTGTCCTGTGCACTCCTGCCCCTCG ACGCCCCCTGTCTCCGCCTTCCCTGGGCCTGAGGATTGTCCCCTTGCAGGCAGCTCTCAT GCTCCCATCTCTGTCTCTGCTGCTGTGTGTGCGCGTCAGACCCCGAGGGCAGGTTGGAGT GACGGTGGACGTGATCAGAGGCAACTGAGCTGTCTAAGTGCCTTCCTTGCCCTCTGCCAC GCTAGCTGTAGCTCAGCATCCCAAGGAGTCCTGGTGAAAATACAGACACAGCCTACTCGG TGGGCTCAGAGAGGGCCGAGCAAACCGCATCTGCTGTGTGCGCCCAAGGAATGGAAAGCA AGGACTTGAGGTATCTGCACACCCACGTTCACAGCAGCACTGTTCACAGAAGCCAGAAGG TGGGAGCAACCGTGTCCATCAAGGGATGAACGCACACACAAAATGCGGGACTCACAAAAT GCGGTATTCACATACGACAGAGGAGTATGTAGCCTTGGAAAACCCTGACCCCTGCTACAG CAGGGAGGAACCTTGAGGACTTTATGTTAAGTGAAATAAGCCAGTTACAAATGGATAAAT ACTGTGTGATTCCACTCATATGAGGTACCCAGACAGAAACAGAAAGCAGAATGGCGGCTG CCCAGGGCTGGAGGAGGGGAAAATGAAGAGTTTGTATTTCACAGGTAAAAAGCTTCTGTT TGGGAAGATGAAAAGCACCCTGCAGACAGACAGTGGTAATGGCTGCAAAACAACGTGAAT GTTCTTAATGCCACTGACGTGCACAATGAAAAATGGTTAAGACGGCAAATTTCATCTGAT GTGTATTTACCAAAATAAAAAGCAAAACCCCATGCTTGTCATCAGGGGAGAGGAGGTGAG GGTGGAGGCACAGCGCACCTCCCCAGCTGTAGGACAGGGGGAGGGCGTGGTACTGGCCGT TTCTCCATTTGCTGATCACCGTGAGAGAGCCTGATGGGGTCAGGCGGCACAGTCTTTTTA CCACTGAACAGCCACTTCCTGCTGCCATGGCCATGGAGCTGGGCCTTCCACCCCCACCTG GAGCCTACTGAGGCCCAAGGAGAAGGCACAGGACCCCACGGCAGGCAGGATGTATTTCCG CTTGTCCAGGCAACTAAGCCACGTCCCCACGAATGGAGGCTCCTACAGAGACAGGCGGGT CGGGTGGTCCAGTAGGACCAGCAAGCGCTTCCCCAAACCCACTGGCTCCTCCTCCTGGGC GCGAGGCTCCCTGTGTGGCCAGCTGCCCTGGTGTGGCCATGTGACCGAGTTCTGGGAGAT GGCGGGTGGGCACTGACCCGTAACCCCCTCTGTGCGGCCCTCCTCTTCCTACCCCCTTCT GCCTTTGAGGATCAGTGCCCATGTGCCCTGGAAGCCTCCACCAGCCTGGGTCCCTAAGTG ACCCTTGGAACAGAGTGTCATTCTCACGAATGTCCACACCAGGGGCCCAATCTTCATTCT AATGAGAAGTCCACATTTTAGAGATGTTGTAGGTGCCTGCCCAGTCTGGCTGAGGCCACT GAACAGCACGATGGCCCCAGAAGAGCTTCTGGGTCCCCTTCTTTCAACAACGAGGCTGGG GTGAGGCCCCACAGTGGCTAAAGCGTCGACCCTTCAAATCTCCAGGGCTCCCTTTGTGTC CTGGAGACCGAGAGGCTGGTGAACAGATGCCAGTACCCAGTGGCTTATAACTTGCTCAGG CTATTTCATTCTCTTTTCCTTTCAGATCTGAGGGAGAACTCTCCATTAGCAGAGGGGAGG TGACCACGTAAAAGGACCCAGGCTCCCAAGCTTTGTGGATACAGGGGAGGGAAGAGGACA GAAGACCTGGAGGGGTGTTTGCAAATACGCACCTGCCAAGGGTAGGTATCTTACCCGGCC AGACAGGGGCCCTCTTCCTCTGCCTGTTGCTCCCAGCTGAGGGAGGAGAGGACTGACTGG GCCTGGATCCCACAAGGTGGTTGGAGGTCCCGTTAGGAGCCAGGGCCAGGGAGGCAGCCC CCTAAAGGCCAGCGTGGATGCCCGCCCACCCACCCCTGCCAAGGGCTGCTTGGGAGTATT GCAGGCCAGACCAGAGTCTCAGCCACAGGTGGAGACAGCTTTACAGATGAGACGAACCAC TTCTCTTGTGGATTTTCCACGGTGACGAGTCAGCTGTATCACTATCATATCCCACAGATG CAGTCTGCACACCCCCCAAGCTCAGGGCATAAAAAGGTGTCTTCATGGAGCAGTGCCCAC CTCTCCACAGCCTGTAAAGCTGCACCAACAACTCAATGACATTCCAGCAACTTCGAAGAG AAAGTCCCGTCTCCCCAGGTCTGCCTTCCTGCCTTCCCCAATTCAGATCCCACAGCTCAC GGAATGGCTCTGTGTCAAACTCTGAAGGTTGGCTCACCCAGGGCAGACAGACAGAGGGGC CTGCCCAGGAGCCCGACTCCAGCTTGCCAACTCTCCTGTCACCTAGAATCAAAGCCACCG AGCGGAGAAGCCCCCGGTCCAGCTGCCTGCGTCACTTTACCTTCTTTGAAGACAGCAGCA GGGTCTGGACTGGCTCAAAGTCCTGGAAGAGCTGGGTCTCCTCGATGATGTGAACAGCGT GCTCGAGGCTGATGGCTTTGTGCAGAGCTCCCCGGTCTGCAGGGCCAAAGCTACAGGTCA GTGACACTAACCCAGACACAGAAACCAAGGACAGTGACCACAGCGGCAAACTTCACACTC TTCACTCTCAAGTCATTCCCTCCACAGATACTTAGAAAACAATGATGATTTCGCATTAGA AACAAAAAAAGGAAAAGGCTTTGGCAAAACAGACAACTGGAAACCCAAGTGTTATGGGTT ATTCCAGTTTTTTTCCAAGGAAAATAAACTGTTCCATGGTTGACCCCAAGAATCCTCACC AACAGTCGACATTACACTTGAGGCTAAGTGCCACATGAGGGGGCTCCCATGCTCCACCAG CCCTCGGGGTGTCACTGGTAAGTGCCCTAGGCAGGCGGTGAGGACAGGGGGCATGTGAGG TTGGCTGGGAGGCTCCAAGGGCAGGCCACAATGCGCTGCCAGCCACCGTGGCTCCTGGCC CCTGTCCCTGTTCCAGAAGTGCTTATTTCAGAGTCCACATGCCAGGGCACATCTAAAACC TGGCTCCTCGGCCAGGAAGCAGGGACGTGGTCCTCTGCCAGCAGTCAGGAAACGCCAGGC TGACGCCTCCTCCCAGGTGGCTCACACCTGCCCCCTGCGTGGGCACTGCCCCAACTCCTC GGCGGCCAGTACTCCTCTGCCCCAGCCCAGCCCAGCCACAGGCCAGGACTTGCATTTTTA TTTTTAACAAGTACCTCCAGTAGCCTGGTGGTCCCAGATCTGAAAGCCACCTGGTGTGGT GACTTCTCAGAAATCTTCTTACGCTCCCACAAACCTCCCAGGTCACCTCGAGGGAGGCAA TGGAACTACTCACGAAAGAATAATTGGATTTCCCAGTTTTCCTACCAGAGGACACAGATG TGCTGTCACTGTCAAGCCTGCCAAGCCCTCGGAACCCACCTGTGCTGACAAACATGACAT CATAGACAGTCCCATCCAGGGCCTGGGTCCGGTCCACCACGATCTGGGTGTAGTTCACAT CTTTCTTGATTAACCTGGGCCTGTTGTCTATTGGGGTTACCGAGTCATCCATCAAAGGGT GGTCTTTAACGAACTGCAGCGTCTTGTCTGGCAAATTCAAGGAGCTGGTGTAGTTGGCGG CCCGTGCCTCGCTGTCGATGCACTGCAGGGAGAAAATCCCCGCTGTTAACGTGCTCGTGT CCCACCACGCAACGGGTGCTTCCACACAAGCAGCCAACGCAGGGGGGGCTGCAAAACCTG GAAACCACACAATGCATGCCTTGAAATGAGGGTAGCAGTGAATAACTTTACTATGAGGAA AGGTGGCCTCTCCCCAGCCAGCAGAGGACACAGTTATAAAACACATCTGCAAGACAGAAT TGCATTCACGATACATACTCAGGGAAGGAATTTTTATCTATTTGTAAGTGAAAAACACTT ATTGAGCTTTTGAAATTAAAAAACAGAACACTGATTTGCAGCTTTCTCATGAAAAGAATG CTAAACATGGCTAAAACCAGGACAATTTAAAATAGCATAAGAGCCTGAGGGATTCTTTTT TCCTGTTCTAGCTCCCTGATGTGTGTAAACCAAAATCTGTGACCATGAGTGAACACATTT TACGAAGCTATGCATAGAAGGAGCCATGATGGTGTCAGGGACAGCTGCCCTTGGGAGGGA GCTGGTGCTGCAGTGAACTCTGAGGGCCAGGACACCCCATGTAGGTCACAGCCCCACAGA GGGCTGTGCACATGCCTGTCACACCCATTTCCCCATGTGAGGGAAGGAATCGGCCTGGAA ATTCCCAATTTCTACATAAAGTTCACTATATTTAGGAGGAAAAAATGTGACTCCTGTTGA CTAGTGGACAGTGCAGAGGCCTTTGCCAAGGAATCATGTGTTTCTCTGTAAGAAACTGAA AATGAAACAGACCTAATTGTTATGCAATGTTAATTGTGCAAAACAGCTGCCCCAGCCTTC TTGTTTGTGCAATAGTGTAGCAATGGCTGTTACGTAACATGCAAAAGGGAAGAAGGATGA GCTGTGCTCATCGGCCGTCCCTGTCCCAATGCAGAGAGCCTTGGCGTGGCCAGGTACCCA GCCCATGAGCAGGCCCCAGTGCCTGTACTGGATTCCATGCCCTGGGCCTTGAAGGGAAAG CACGGCCCGCCCCCAGTGCCCCAGCTCACCGCTCCAGGCCGCGGCTTGGGTACCGGGCCA TTATAGCGCACCCACTTGGTGTGGGACTGCTCCACTGTGGTGCTCTGCATGTACTTCCCG TGGGAGAAGACCTCCTCGGCTGTGGACAGGTTGTAGGCGCACACTGCCGACAGCCCCACG TTGTTCCTGGGGAGGGGAAAGAGGTGACGGGACCACCTGGCGGCATCAAGGGAGCAAGGA GGGGGACTCCACCCAGGGCACTTACAGCTGTGGGGTGAAGAGTGCATAGAACACAGGCAC CTTCAGGCCCGGGGACCTGAGCACGAAGACATCCCGCAGCACATTGAAGACCAAGCCGCT GTCTGGCCGGGAGCAGATGAGTCGGGCTTTCAGGAAGGAGGTCCATTTCTTCTGCAAGGT CCTCAGGCCGCCCTGGTCCCCCTAAAACCCCAACAAGAAGACGTGGTGGGCCGAGAGTGG ATCCCCTGTGAGCAAGCACTAAGGTCAGAGGTGCACCCCTCCATGGCCCAGCACAGCGCG GCTGTGCCTGACTGAAACAAAGCTCGGGCAACAGGAGACAGATGCCGCAATTATGTGAGT GGCCCGCAGCACCACGTCCAGGTTCCAGCTTGGATCCCAGAACGCTCCTGGGTTAACACA CAAAACAAAACGGACAAAAGCCCTCTCACTGAAAGCTCATTTGATCGTCCATGCCTGCCT GTGCCCAGCATTCAGTCCTGCAACCGCAGAGGTGCTGCCGTGCTCACACACTTCCAACTG CCAAGGCCCCTGGCATTGTGTGACTTTCCTGACATAGGGCCCATCAATGAACATGCTCTG GGTGGGGCAAGTGGCGGCAGCCTCCTTCCAGGGGACAGCCACCGGCCCTGCAGCCTGTCT TGGGCAAATGTGTGAACCTTCCTCCCTTTAAAGGAATAGATCCTTCACTTCCTTTCTACC CAAAGTATCTGCTAAAGTGCTTTGAACCTAAGTTCTTTATAAACGCTTTTCAGGGATCCG ATGACCAAGACACAATTATAAACTACACATGACTGTGTGTGGTCTGGAGAGAAATACTGA AACCACAAAACCTGAGTGCAGAAGAATATGAAATAGAAGCAGCCTTACTTATTTTGGACA CAGGGAAAATGTTCCCCCTTCATCTCTGCTGTGTGATTACAGGAGCCCAAATTCTCTTTT TGATAAAAGGACTTCATTTTCCTCCTTGATGTTTTAGCAAAGAATAATTTCTAGCACATT TTTCGTCAGGGGTCTCATGTGGCTTTCAGGTCACGGGCAGCAGGTGAAGGGTTCATGTGT GCCTGCGTGGTAGGCAGGAGCTGTGGGGCCTAAGCTCAAACCACCCTAGTCCAGGAGTTC AAACAAGTATGGGGAAAAAAAAGGGATCAGAGGGGATGACAGCAGTGTGCCTAAGACTTG TAGAAACTTGTCGGGGGTGGAGGTGGCTGCTCTGTGCATCGCTGAATCTGCTCACTGATC CTGCTGCAAACCCTCAGTGCTGGGTAATAAGTCAAGGTCAAGGCAAGTCTGATCCTTGGC TTCCCGATGGCAGGGGAGGGCTCGAGTCCCCTGGCCAGTGCTGCTCTGACAGCATTCTGA GCACTGTGCACGCCTGCCAGGAGCTCTGGCCCTGCAGCACCCTCCCCATCTCAAGGGGCA CTGGCTTGCCCCCAACACTGATACTGTTGATAGGATGGTTTCCTGGTCTGCAAGACAGGA GCATGGCAGCCACGGCTGCGGGGCTGCGGGGCAGCTGGAGGATCTGGTCAGTGAGCCCTG GCTACGGAAGGCCTGGGCAGGGAGCAAAGCACCAGGTGGATACTCAGGTGTGCACATCAC CCAACCTTCTTCCTTATGCAAGGGGCTGTTAAGGGAACGGTGTCAAAGGCACCCACTTTT GTGCGCCATAGGCATGAAAGGAACCCTGCTTCTCTGATGTCCTGATGGTCATGACTACAT GAGAAAGGGCCACGCAAGAACTATCTACCAATTTCCATGAGAGACGAATGGCTACCTGCT CCGAGATGAGCTCCTGGCCAGGGACATGGCGGCTGTGTTTCATGTGGTTTCCCCCAGCTC CCCTGAGGCCTGACAATCCACCTCCTGGAAACTGCCACTGAGCAACCTTGAGATTTCCTG TAATCAAGCCCATAGGCCATTCTCTTGTGCTGAGCACTGTGCCTACAGTGTGTCATTTTA AAGGCACCCTCCCCTTTTAATGTACTTAAAGATTTGTGTTTTGACAAACTTCTGTATTGG TTCTCTCTTCTTAATCTTAAGCTGTCGGTTAATGTTTCACTCTTAGGTAGATTAAGAGCC AAATGGTGAAATTCCAACAGACTCTGGTGAATACATTCCACAAAGCCTTGCTTTTTATAA GCTAGAGGTTTGAAGAGGGTGCATTAAAAGAAAGAACCTCCTGAGAAGAGGAGGCTAATG GGTCACACATGGGGGCCAGCACTCCCTCAGTCCCCACAACCCCCAGAAATAAGATCCATT GAGAGCTGCATCTGAGGCCCAAGGGAATAAAGTGCTAGGGAAAGTGACATTTGAGACGAA GGTCAGGAGCCACCCATCATCCAGGCACACTATTGCCATGGCAGGGGCCAAGCGAAGCCA GAGTGCCTGGCACTCACCTTGCACACTCTTGCTATCCGTGGGATCAGCACCCTGAACACA AACTCATACTCCACAGACACCTCCGTGAAGAAGAAGTAGACCCTGTCATCCTCGCCGTCG GGGCTGTCTGGGCTTTTTCGGATCACGTCAGCAAACACGAAACTAGGCTCTGCAGAGAGA GGACAGTGATTATCCCAGAACACAGAGCTGGGGGACTGCCTGCACCCATGAGGTCACGAG GCCGGCCAACACTACCTTGGGGGCCTGAGGGCTTCCCTGCAAGGATGTCTGGAGTGTGCA CATGCCACAATCCAAACAGAAACTCCAGGATCTGAGGATGATGACAGCCCTGAGCCCAGA TGGTGCCCTACCCCCACCTCCTCGGCCTCAGAGAGGTGCCCCCGACAGTGGTTCTGCAGT GCATCCCACCCAGGTTCACCCCAAGAACTGAGGCTGGGCCTCCTGACTGGAAGGCAGGGA GCCAGATGGTACCAGCATCAGAGACCTACGTAAGGCATGCATTTGCTGGTTTAAACAACA CATGCTTCACATAAACAAACTCTAACCACCAGATCCTGCCCCACCCTGAGGAATGGCCGA CTGTCCCTGAATCTGGGGTCTTGGGATCTGCCCTAAGGTCAAGAGGTTCAAAACCCAAGG CTCTACTGGCTGGCACCCACAAGAAAAGCCCCCATGAACAGCCACCAGCTTCTTCCTGCA CATTGAAGACGGACATCGGACATGTGCTGCTGGCAGCAACAAGGCACCCAGAGCCCATCT GACCGGGCACTAGAGGCTGGGCCCGGAGGCAGGTCCCACACCAGTGTTGGTGCCACACTT TAATATCATTCTGGAAATTATACCATGTCCCCATCTGATTAGTCTTAGTTTACCATCTAC TATCAGATTCTCAATTTTATGAGAGTCTCCCAAATCCATTTTTGGGGGGTTAGTGGGGAG CTGTCTTAAAACAGTACTCTGTTACCAGTGAAAACACCCAACAAGGTGCCCTGGGACTCT GGCCATTGCTGGACAGTTTGGGAAGTATCCCCCACAAACAGGGGCTAACACAAGCTCGGG GGCCCCCAGGGCTCAGAGACAGAAAAGGAGAGATCAACAGGTGTGCACTCATGAGGAGAC ACGCACCTCCCACTAAGGTGCACTGCTCTTCCTTACCGTTCAGCCAAGGGATTGCATATT CTGTCCTCAGAGGACTGTGGGAAGAATTTCGGGAGATGATGGGTTCACTTCCCAAAAAAT TATACGACGTCCCCGAATAAAGTTCTCCATCTGCAGGGGCCCAGAAGAAAAGAGGAAAAG GGAACCAACCTCTCAGGCTATGGCACCAACACTGGGACAAACATTCAACACGGTGTTTTC CTTTATAACCCAATTAAGTCCCTGCCTGGGGAAAGGGAAAGACAGTCTCCTCAACTTTTG GGGTGTCCTGTGTCTTCTAGTTCTTTCTTTTTCGAGATGAGGTTTTTTTGTTTTGTTTTG AGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTGC CACCTCCACCTCCCAGTTCAAGCAATTCTCCTGCCTCAACCTCCCAAGCAGCTTGGACTA CAGGTGCGCGCCACCATGTCTGGCTAATTTTTACATTTTTTGGTAGAGATGGGGTTTAAC CCTGTTGACCAGCTGGTCTTGAACTCCTGACCTCAAGTGATCGAGGCATGAGCCACTGAG CCTGGCTTGAGATGAGTTCTTGCTGTTTCCCAGGCTGGTCTCAAACTCCTGTCCTCCCGC CTGAGCCTCCCGAGTAGCTAGGACCACAGGTGTGCTCTCACTTTGATGGGGATAATTTCA TGCTCCATGTTCAGCTGCATTTTAAGAGTCATGGGGCAATAAGTAAACATGAGCAAGGAA TTCCCACATCCAGGAAAATGCTGGCAGATGCAACAGTGGGTACACACCAGGCTATGACCA CTTGCTCAGAGGTGAGAGACCACTGCAGACAGCATGTGGCTCAGTCAAAACCTTACTCTC AAACAGGAGCATCTGCTCAGCACGCGGGGATTATCCAAATGACATGAGCCAGCAATGGAT ACAAAGTGACGTTTACCATGGCGGCTATTATCCTTGCAAACAATGAATTCAAAAGTTAAA GGGTCTATGCAGTCACATGTGCCTTTTGTAAGGATAGCTCCTATTTAAACAAAGCCAAGG AAGACAGCACTTCAGAGAAGATCCAAATATCCTGTTTGGTAATTAACATGCCACTGTAAT CTTCACGGTGAAGGAACTGGAGGGGCAGGACTCACCAACCATGACGGATGTGTAGCTGTG TGCTGGGTCAAAGGGACATCTTCCTTTGCCATCTTCATTTTTCCCCAGAAACTTAAAGGA TGTTAAGTTCTACAATTGAATAAAAAGAGAGCACATCATCAGATGGCTGAATTTCTATAG TAACAATGTGTCTCTGTACCACTTCATTTTACAAATTTGCTCTTCTCGGAAGACCAACAG GGCCGAGCAGATAGGTGTGGAGCTACAGGAGTCCCGCCCACTAGGGCCAGGGCTTGTGTT GCTCAGCTCAGGTCTAGACATCAGCACCTTGGTGCCCTTGCTCCGTTGCCCTGGCCAAGC TTCTCAAGATCTCAGACCCTCAATTTACTCATCTGCAAAATGGAAATGGCAACGCTGATG GCTCTAGGGCTGGAAAGCCACCAGGATAAACCCAACACAGGACGTGCTCAGTATGTAATC GGAAGCCCATGAGCAGAATTTTAACATCAATAAAGACGGCATTCTAAGCAGCTAGGTGAC CCAATAAATAGGAAGCAGAAAAACATAAACAGGCAGAATCTCTACGTCGCTCCACCCACC AAAACACACTCCAGATGGATCAACCATCTGAATACTAAAAACAGAACCGCACTGTACTAA AACAGAGCAGGGGCTGGCGTTTCCATCTGGGGGTCCTCTCTTTACCTGGCCAGAGTGCCC ACAGCCACATGAGGAAAACAATGCACAGATCCAACCACAGAGAGAACTGGAAAGTTCCAC ATGGGGAAATAATACGGCAAGGTTAAATATGTGACAAACTGGGGGAAATGCCTACAGAAT GGCAGATGAGGTGTCTCCATCCCTGAACATGTGAGAAGTGTGGACAAACGAGTGAGAAAG GGCATCCAGGAGAAAAACAGGCAAAATCCAGCAAGTGACAGAAGAAACCCATCTGGACAG CACAGACGAGAGAGGGGCTGAGCCTGCCGGGAACCAGAGAGCACACAGAACACGCGTGGG GATGCCACTTTGCAGCCAACAGCCTGGGCATGCTGAAGACAGGCAGGGCCCACGGCGGGG CAAGGGCACCCAGCACCTCTGCTGCAGGAGGCTGGCTGGAAACACGCTCTCGGAAGCAGA GCAGGAAGGCTCAGACCACGTGGAAGGCCGCAGCTGACACCCTTGAAAGGCCAGTTAAAG CAGCACACAGCTCTTCACCTGTTAGGTTAGGGAATGTGAACCCCACTGGATGTGACCATT TAGCATACCTTGAAAGGAGGTTTCGGGGCTGTTGGGGAAATCTGAACGGGGACTGGAGAC TGGATGATGCTGGGGAATGATTGAACGTTTTCTTAGATATAATGATAAAACTGAAGTTAC ATAGGAAAATGTTACTATTCTTAGGAGATGCCTGTGAAGGCATTTGGGAGTCACGGGTCA TAGTTCAGCAAGCACACATATGTACACAGACACACATGTGGACACATAGACATGCACAGG CACACAGACACGTGCACACACACACTCCCAATTGTGCAATCTAGGTTGCCAGGATATACA AGTGATACATCTTTTCTGCAGCTGTGAAAACTTTTATTAAAAATATTAGGAAAAATTGAC GGGGCGTGGTGGCTCATGCCTGTAATACCAGCACTTTGGGAGGCCAAGGCGGGTGGATCA CCTCAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAA AATACAAAATTAGCCAGACGTGGTGGCACATGCCTGTAATCCAGCTACTCGGGAGGCTGA GGCAGGAGAATCGCTTGAACCCAGGAGATGGAGGTTGCAGTGAGCCGAGATCGCATCACT GTACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTCAAAAAAAAAAAAAAATTAGGAA AAATTATAGGTCTAAATTTAAACCAAATACAGTATCCTCTAACCTCAACAGCTAACCTAT CTACAGAATGTAAGTTTAAATGACAGAACTTTAAGCTTCTGATTGAGTTTAGCCAGAAAA ATCCTTTGTTGTGCAAAATGTTTCTGGTCCAACCGTACTTTCTGCACAAAAGTAAATACA AACGACTGTCTTTGAGGACTGAGGGTCTTACTATCCCCAAAGCACCCCCACCCCCTATCA GGTTTCGTTGCCAGCATCTGTGGTACAGGCAGCTGGGTAGACCCCTACTATGAATCTCAC CCCAGACGTCTGTGTGCAAATACCAGGCTTCCTCATCAAGTCTCTAATGAGGCCATACGT TGTCTTGTCATTTATCTCTGACTCAAGATTGGAAAATATTTTAATTCCAATTAATTTAGG GTTCTAGCAAATGATGCTTTTCACTGTGGCATATTTTACATTTATCAGGACTCATTAAAA TCCAGGGATACACAGTAGAAAATGTGCTTCATTTTCCATGTTCACATGGACTTATTTAAA ATGCTACTTCTCCCTCTCTGATGATCATCACATTGCTCATCAGATTATCTGGATAGAAAG GACCGTCACACAGGGGGAGGTGCCGGATACCAGGCTGGGCAGTCAAGGATGTGAGCCGGT GAGGGACAGAGGCCGGACTTGCTTCTCAAGGTGCTCAGCACACTTGACCTGCTGCCCCTG AGTGGGTGGACCCAGGAGTGGTTCAGTGAGCAAGCTGCACACCACAGCCGACCAGAAGGG TGGGTCCCACAGCCAGAGCACAGATGCACCAACCAAGAACACACAAGCCAGGAGCAAGTC CTGACTTTTCCACCTGACCCAGATGCCCAGAGCTGCCAGGCTGTCTGTCCTTTCCAGCAC GTCCCCTCACCCCATAGCATGTTCAGGCTACCTGTCCTTCCCAGCACATCCCCAATGCCA TGTTCAGGCTGTCTGTACTTTCCAGCACGCCCCTCCATGGCATGCTCTGCACTAGCACCA AGGGCTCCCAGCACCTTGAGCTGCACCCCAGGCCTCACCCTTGGCCATGGACACCGAAAC TTAGAGGAGCCAAGTGGGCTGTGTGCCCCTGACAGCAGCTGTGCAAGACTTTCAGAGGGG CCACAAGCTGCCCCCGTTTTCTGCAGCTGGCTCTGAGAAAATCCTATTTTTTTTTAGGGT GGAGACAGCTTTACGTCTGCTTTGAGCCCCCTTCTACTTTAACTGCTGACCAGGCTGGCG TGAGCACAGGGAGGTGCCCATCAGCCTTACCAGGTGGTCACAGGCCGGCTGGAATGCGTT GGTCCCACACACGTAAAGGGAAGTGGCGCTGAGTGGCTGCAGCACCCGGATGTAGTTGAG GCACTCTGTCTGCAGGGAAGAGAAATGCACCATTAGCAACCGTCCAGCCCAGATGCCCTC CACTATTCAAACTGCTCACGCCGTTCATCTCAGGGGCACAGACCCACATTCACCAACACC AGCTCACAGGTGGCCCCAGGCCAACGAGGCATGTGTGCATTCTCAGCCTTGTCTTGTCAT CTAGACCCTCTGCAACTCCTCTTCACACACTGGCCTGTTCTCGTACAGTGGAAGGTTCAC TGAGACCCCAACCCCACCCCTAGGCAAACCTAAAGCTGAAACTGGCCTGAGTAATTGTGT CTCTGCAGTGTCCACATGCTGTTCAGGTGCCAAACAGGATTTTGTTTCAGTCCCTAATTG ATACTCAGCAAAGATGTGGTGACTGAAAAAAAACTCAATGAATGCTTACCTCAAATCTTA CTGGGACACCCACTGTTGAAAGCAATATATTTTACTCTTGCTAAGTACGTGGACCACTTG TTCTGTTGCCAGGCCTGGAGAAGTGTCCACCCTACAGAATTTCCTCTCTGTTTCTGGAGA CCCCACCCTGCCTCCAACTTGCACAGAACTAGGAACAGCGACACTAGGTCTACCCAACCC AGGGTCCCAGTCCAGCCCCCATGGGAGTGGCTGCACTAGGAGAGCCTGGAGCCCGGCTTG GCATCAGAAAGGCCCAAGCAGGAAAACAAAGATACCATTTCAGAACCCACTATTTTAGGC TAAAAGTACTTGCGTTACATGTGCTATAGTCTGAAATTATCCCAGATTAGGAGAGTTCTC TTTTTTAGACTGGTTGGAAGTAATTCACTATTCACCCCAACCCACCTGCACACCCCCGGA AACCGGAGCTACACTGCACCGCCTGCTTTTCCTCTCATTTCCTAATCTAACTTTGGATTT AGAGACAAAGACTTCAGTGCAAGTGTTTAGCATTTTGCTAAGAAAGTTTAGCATAGACTT CTTTGGGTTTTCTTTCTTCTTTTGCCTTTAACTCAGCTTGTCTTGACCACCATTGAGGAA GAATGCCCAGTGCCAGGTAGGGACATGATGGCTCAGAGGGTGATGAGGGTAACCTAGAGC TGCAGACGGGAATGAGTATTCGGCCCAGGGCTCCCTGAATGAGTACCACACTGAGGGGCC TGAGGGACCAAAGGGACGGACGTGTGCCAAGAATCCAAAAGTCCCAGTGATAGAGAAAGG AGCCAGAGAAAGTCTAGGCAGACAGGGGCAGGTCCCTGGCAAAACCCCACATGTGAGCCA AAAAGCCTAAAACCCGCAGCCCAGAGTGAGAACTTCTATCCCTGTTTGCCCGCCGTCTCC CGATTGGTTCTTTCTGAACATCTTTTTACAATCAGATGTTGCCTTTTCCGAAACTACCCA CAGCCCACCCTGCCCTCATCCTGTGCCTATAAGAGCCCAGACTCAGTTGATAGAGAAGAG AAGGTGCTGGACTAGAGAGAGGTGACTTGACTTCAGAGGGATGGCTGGATTTTGGAGAAA TGGCTTAACTTTGGAGAAGAGCCGGCCAGAGCTGGCCAGACTTCAGGGAAGATTATTTGC TCGTCCTGTTCCCTCTCAAGCTCCCATCTCCGCTGAGAGCCACTTCCAACACTAAACAAA ATTCTCTGACTCCACCATCCTTTAAGTGTCCATGCAACCTCATTCTTCTTGGATGCCGGA CAAGAGCTCAGGACCCTGAGTGTGTGTACCCAAAAAAGGCTGTCATACTGGCCCTTTGCC CTCACTGGCAGAGGACAGCTGTCCCACACAATGAGAAAAGGGGCCCACTGAGCTTATAAC ACACCACTGTCCATGGAGAACAGAGATAAGAGAGCACTGTAACGCACCCTCTGGGGCTGC GGGGGTCACAGGCACCCCAACCTGGGTGCCACCCTCAGGGCTCACACAAAGCCTGCTCCT GCTGGCACCCAAAACAGCTGGCCAGATCCCACACTTGCTCACTCATGTGCTCCCTCCTGC AAGAGGTTGAGCACAGCAGGCCGAATAAATGGGGCATCTCTGTCGCAAGTCCAACGAAGG GGTTGAGAAAAACTGCATGACTAGCAACTCCTCCAAGCCTAAGGCCTCTGGGTGCAAGGA GGCAGAACAAACCCTGAATTTCTGCACTATTCACCAGTGGGCTTCACTATTCACCAGTGT TCTGTAGTCAAAGTTTCAGGCCATCTGAATACATTCAATTCATATAAACTTTAAAAAAGT ATTTCTCAAAGGCCAAATATGTTTGGCACCTGCTTTGAGAAACCCAATCCTGATACTCAG GAATAGAGGGATGAGCTCCAAGACGCATCACAACAAAACCAAGCCCAGCAGAATGAACAG AGCCTGGAGAAAAGGCTGGCCTGCACTGCAGGCATGCTGGCATTCAGTAGATTAAAACAA CCAAGAAATACTTGAATGGGATTCTTTGTAGCTTGCAAAAGAAATTTACCTGTTTTGATT TCCCCTTTTCTGCACATTTTGCTTTTTTGTCTTCTGAGACCTTCCAATACACCTGTTGGG ATAGAGTCCATATCAGTGCATATTCTTTTAAAGAGATACTAGTATAAAAATGCACAATTT TAAAAGCACATGATAGAGTTTAGAGCCTAGAGGTTTCTCCTGAGATGATCAATTCTCAGA CTGCAAGGGAGGTTCAGAGAGCAGGGGAGCAGCCTGGGGCCTTCATGAACATCCTCACTG TGATCCTTATCCTGAAACCAGTGGAGTCTGGAAGACCAGCTCCAAAAGTTCCATCACTCA CCATAAAACAGCAGCAAAAATCAAACTCGTGAAAGTGGAGAAAATTAAATTATTTTTCAA AAACCTAAACCATAAGTATTTTCAAACATCAAAGTGGGCTTTTTTCCATCCATTCAAAGT GACTCTACAGGCCGGGCGCAGTGGCTCACACCTGTGATCCCAGCACTTTGGGAGGCTGAG GCAGGCGGATCACCTGAGGTCAGGAGTTCCAGACCAGCCTGGCCAACATGGTGAAACTCC ATCTTTACTAAAAATACAAAAATTATCTGGGAGTGGTGGCGGGCGCCTGTAATCCCAGCT ACTCGAGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGGAGGCGAAGGTTGCAGTAAGCC GAGATCGCACCACTGCACTCCAGCCTCGTGTGCCTGGGCAACAGAGTAAGACTCCGTCTC AAAAAAAAAAAAAAAAAAAAAAAAAAGTGACTCTACAGTCCAGTTTAAAAAAAAAAGCCA CAATATTCACTGTATCAGTAGAAAGGGAGATTTACGATTCCTTAAACTTGCATGTTGGCA GCAGGAGGAAGTGATGAACTAACACCACCAGCTCAGCTCAGGCACCATCTTAGTAAGATC CATGTTCCTACCACCTCTTCTTTCAAACCAGGGACAATTCGTGATCAGAAACTTCCAGGG GGTGGGGGCCTTAGCCCCTTGCCCTCCAAAGCCCCCACAGAATAGAAAGCAACATAAGAC AAAAGGGAAGGTTTCTATATCTATCTCTGCCTCACCTTCCCCAAAATGCCCCCTCTCTCT GTGATGTTCCATAACTGATGCAAAAGAAACCAGTAACAATGTATTTTTCTCCACCAAAAG GCTTGTAGCAGGTGTCAGGACTCAGAGGTTAGGAAGCACACAGGGCTTCTAGGAGGGAGA GTATGAGGAGAGGAACCCCACTTTAGGTTTCTAACTAACTCTGTGAGTTCCTGAACAGCA CCCAGGCTGCAGACACAGTACTAAGGGAGTGTCATTTCATAGAAATGGAAGTCCTGATAG GGGCACACAAAAGCGGAACAGAGTCTCATTTAAAATAGCCACTTCCTTCAGCATTTAAAG TACAGATGATTTCGTCAACTCGCATGAAATGCATAAGGACAAGGGAACGTACACTTCAAC AGACTCTTGATCACGTTTGCAGGGATTTTCACTGATGCTTGGCGGGGGTCTCTTTATTTT TTTCTTTTAAGTATAAGAGGTCCCCAAGCCTCTCCCCAACCCCGAGGGACCACCATGGTG TCATTAACAGAGCAATGTCTGGCTCTCACTGAACACCTGTGGGGCCAGCACAAACACACT GTCCACAATTCCCCCAAGACCGAGTGTGAGCCTGTGTGGTCAGGAAGGCGCTCAGAGGAA GAGAATTTAACAGACACGCGAAGAGTAAGAGCTGAGTGAGGTGAGACCACCACATCTTTC TGCTCAGAGTGCCTCACAGTGCTGAATACTTTGTTTTTGTTTTTTTGAGACAGGGTCTCG CTCTGTTGCCCAGGCTGGACTGCAGTGGCATGATCTCAGCTCACTGCAGCCTCGACCTCC TGGGCTCAAGTGATCCTCCCACTTCAGACTTCCAAGCACCTCAGACTCCCAAGACCTGAG CCACCACACCTGGCTATTTTTTGCAGTTTTTGTAGAGAAAGGGTTTCGCCATGTTGCCCA GGCTGGTCTCAAACTCTTGAGCTCAAGTAATCCGCCTACCTCGACCTCCCACAGTGTTAG GATAACATGCGTGAGCCACAGCACCCAGCCAAATACTTGTTTTCAGAGCATAATGCTCAG AGCTCATTTATGTGTCAAACAGAAATTGAGAAATAAGCTAGACCCTGGAGATGAAAACAA AAAGAGATCTGGGCAGAAAATGTCCAGCGTGAACCTGGAACAGATTCCAGAGAGCAAGAA AACTAACCCCACACCGCGAGGTCTCAGGAGCCAACCCAAACAGGCTGCTGTTGACCATGG ATGCGACGATTTGAGCATGAGGTAGGTGTTTCACTGTGATGGGTCAAAGAAGAGCAAATA TCTTTAAATCTATGACTTCATTGTGACACTAAAAATCAATCAAAAAACTCACTCTTGCCC TTCAGAGGGGAAACTGACTCATTAACTCATTATTCTGAAAACTGGTAAATAAAGGCAAAG ATTCCAAGCATCGATTCTGCATTTCCCAAAGGAAATGGGACCTCTACGGACCAAAATAGC TGGTGATGGGCACTTCCCCTTTTATACGATTTCCAGCTAACAAGTAGAGAAGGAGAGGTA GAATCAGAACATTGCGTTTTGCAATCTTTGATGAGAAGAGCATCTAGACTTCGCTGGTCA AAGGCCACCGAGACTGAGGAGGAGGAACACCTGCCTCCATGGAGAAGCCCGCCTCACAGC CCTGAGAGGGATGAGCCTGGATCTGACACCCAGCTGGGGATGTGAAGACAGAGGTGCATG CTAAAGACACCATGAGTGGGGCTGGGTGTGGTGGCACATACTTACAGTCCCAGCTACTCA GGAGGCTGAGGCAAGAGGATCACTTGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTACAAT CAAATTTTAAATTCGGTTTGATTTTTTAAAATGTTTAAAGACACCGAGGAATCAGGAGCA ATGTGAAGAGTGGGACATGGGATGGGCTGTGCAGAGTAGCTTTCTCAGGAAGGAAACCGA GGCTGGCTCCTAGAAGCGGAGACTGAATGGACAGGGTGACCAGCTGCAATGGATTGGGAC AGCGTGGTTGCAACCTGATTCAAACTAAACGTTTGAACCAACTAAACAAGCATCATCCAC AAGAGTCGGTGAAATATGAACACTGGCTGAATGTATGATGATATAAATTTTGGAGAAGCT ATTTTTGATTATTTGCACGACAAGGGGCCCTTTCCAGTAAGAGATACCCAGATGAAGAAT GTGGTGTCGGGATCTGCCTCAATGCCCCAGGAGGTGGAGGGTACTGTAGGCAAGACTGAA CACCCGGCCTTGCATAAGCTGCAGTGGGCACAGGGCTCATGGCATAGCTGTCTCTGCTCA TAGGTATGTTTGAGATTTTTTCATAATAAAAAGTTCAAAAAAAAAAAAAGCAAAGAGGGT GGTCCCCGGGTGAACTGCTGGTGGACACCCAAAGATGGGGCTGCATGGTCACAGCTACAG AATGGAGGCTCCAGGTAAGTCAGCCCCCAGCCCCACAGTGGGGCCAGGAGAGGCTGCCCA CTCAAGCTGGGCTATGTGGACATGCAGGGGAGCCCAGGACGTACCTCATGCTGCTTCTCG GAGATGTTGAGTGCGTTCACAGCGAAGACCGCCTCCCGGGCACCTATGTACAAGGTGTCC TTGTCCTCGCTCAGCAGCAAGGCTGAGTAGTTGTAGATGTCTGGCTCATGAAACTGCACC AGGTGCACCTCTGTGGGATGCAAGGGCAGGGTCAGAGTGGGAGGAAGAAAAGAGCGATGG AAGCATTTTTAAACCTGAGCACATCCTAGGTCCCTGTCTCAGTGACAATGAGCACGTCTG GGTGCAGTCATGTCTCGAGGGCCATGTGTTGCTGCAACAGGCACTGCTACAGTGGAGGTG GCCTCAGTCAACGCCAGACCCACAGTGTAGCCATCAGGTGTGCTCATGGGAACCACTCAC AGCCCTAGAGCTCAAGCCCGGAGCCAGTGTGCTCACTTTGAAGCTGTGAGTCGGACATCC CTTCCTGCTCCCTCAGATCCCAGAATCCCAAACCCTGCTCTGCCAGATGCTTCCTGTGAT GGCTCCCACCCTCTGCCCACCCAACTCTGGTCTACATGCCTTGTCATCCACAGATTAGGT GTACAGGAATACAATGACTTAGGATTTTCTTATTCAGGAAAAGAATGTTTTACTTCAAAA TCTTCACAAAATTTCTTTTGGAGAATATATCCATCAACGAATGCAATTCTCAGTGATCAC CACCACAAACTTATAGACAGAGAAACAAGTGACGTCTCTTTGCTTATTAGGTTACTGTAT CAATAGCTACTTAGGAAAATGAAGATTTGAGCAATAGCTGCTTAAGAATAATATAAATGT ATCAGCATTATTTTTTTTAGGACCTGTTTCTTCAACTGTCCTGACAACAATTTGAGCATT TTGACCTTGGCTTTTTACATATTACCAAGAGTCTGCTTTATTTAAGAGTCAGGTGGGCCA GGTGTGGTGGCGGGCGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGTGGGACGACTGCT TGTGTCCAGGAGATTGAGGCTGCAGTAAGCTATGATTGTCCCACTGCACTCTAGCCTGGG CAACAGAGCCAGACCCTGACTTCGAGAAAAAACAAAGAGAGTCAGGTGTTCATACTTTCT GTTCTAATTTTCCCATGTGGAAGAGAGATGCACACAGGCAGCAGGTCCTCTCTCTCAGCA CAACAATGGCCTATATTGCTGACAGCTCTCAGCCACCTGCAAGCAACACCTTGCTCAGGA CCCAGGGTGTAAGCTCTCAATCCACTGAGTCAGAAACCCGGGTCCCCAGACACATCCTCC AAGAGAAGAAATAACTAAAAAAAAACTAAACAGCAGGAAAGGAAAGTAGCTGGCATGAGG CTCAGCTGCACGTAGGACGAGCATTCTTATGATGCCTCACTGTTCTTCTCAGGCGCCTGG AGCAGACGCTCAGTGGGGCGGGTGCTTTGGCAGCACGCCGCGAACATTACTAGGTACGAG GGAGGGAAGCTTCCTGTCAGGGGTCCCCAGATTCAGAAACCAAATCAGGAGGTCTGCACG AGCCTTGCTGAGTATCTACAGTTGTCACAGCCTCTCCCTTAGATCAGCTGAGTAGGCCTG TCTGCTCAGACAAAAGTTCTCAGAGCAGAGAATCCAACAGATCACATGCCAGCATCCTCA GCCACCTGCCTGAGCATCCCAGGAAGTGGAGTTCCTGTCCCGTCCCCAGCCACCCGCCTC AGCATCCCAGGAAGTGGAGTCCCCATCCCGTCCCCAGCCACCCGCCTCAGCATCCCAGGA AGTGGAGTCCCCATCCCGACCTCAGCCACTCACCTCAGCATCCCAGGAAGTGGGGTCCCC ATCCCGTCCCCAGCCACCCACCGCAGCATCCCAGGAAGTGGGGTCCCTGTCCCATTCTCA GCCACCCACCTCAGCATCCCAGGAAGTGGGGTCCCTGTCCCGTTCTCAGCCACTCACCTC AGCATCCCAGGAAGTGGGGTCCCCATCCCATCCTCAGCCACCCGCCTCAGCATCCCAGGA AGTGGAGTCCCCATCCCATCCCCAGTCACCCGCCTCAGCATCCCAGGAATTGGGGTCCCC ATCCCATCGCCAGCCACCCACCTCAGCATCCCAGGAAGTGGGGTCCCCGTCCCGTCCTCA GCCACTCACCTCAGCATCCCAGGAAGTGGGGTCCCCATCCCATCCTCAGCCACCCGCCTC AGCATCCCAGGAAGTGGAGTCCCCATCCTGTCCCCAGCCACCCGCCTCAGCATTCCAGGA AGTGGGGTCCCCATCCCATCCCCAGCCACCCGCCTCAGCATCCCAGGAAGTGGGGTCCCC ATCCCGTCCTCAGCCACTCACCTCAGCATCTCAGGAAGTGGAGTCCCTGTCCCGTTCCCA GCCACCCGCCTCAGCATTCCAGGAAGTGGGGTCCCTGTCCCGTCCCCAGCCACCCACCTC AGCATCCCAGGCAGTGAGGTCCCCATCCCAGGCCATCAGCACCCCTGCAGGTTTCGTCAC TCACCTCTGTGCTCCCAGGTGATCCGGGGTATGGGTGCAAATGCCATCGCTGTCCCAAAC ATCACTGCAAGGGCCATGAGCAGCCCCCTAATGGGGGTGCACATCCTCATCAGGTAGAGG CGACCCCAGGGGCTTCAGCAGCAAAGGCTCACGGCAGCAGGTGGCCGGGCAGGTGTGCTA TTGCAGATGCGGCTCAGCGCCCCAGGACCAGGGCCAGCAGCACAGCCTGGAGCTCGTGAA CAGCGCGGTCCCTGAGAATCCACATTTCCCAGTTCTCCAGGTGAGGAGGGGTCGCTCTCA CCACCGCAATGTCAAAGCCCACTTGATACTTCTTCAGGGCCTCAGAAGAAATGCTGGAAG GACATGAGAAAGAAAAGGCAGGACCCATGGTGAGTGATGACCTGCTTCTCACTGCTCTGT AGCCCCTCTGCTTGCCCTGGATCCTCACCCGGGTCCATCTGCTGAGGAATACGGAAGGCA GCGGGGGACAAAGAGAGTCTTAGAAGTGGACAGCCCAACGGACACAGGAAAGCGAAGCCA GGGTCTTCAGGAGTCAGTGCTTCCCGCTCCTCCAGCTACCAGCCCAGAACACAGGACAGA CACATGGAGAGGACCTGGTGTGGGGCACCCGGCAGACACACATGGCCGGCTGGCTGCCCA GCTTCCTTCCTGTGTGGCTGCTGTGTCCAGCTGGTAATGAGATGAAAATGAAGGAAGAGA ACTCGGGTTTCAGTTTCCCTTAGAGACTCTGCCTTTGTAACGCTCAGCGAGGAAACGGCC AGAAAAACCAGAGGCTGCAGAGAGAGCTAAGATGTACATGTGAGTGCACACACATGCACA CACACAACATATGCGCACACATATGTACACACACACATGCACGGATGTACACCTGTAGAA ACACACGCACGTGAGGCCTCACCACGCAGGAGTGTCTGACCTCCTGCCCCAAATGGGACC CTGCTAGCTCTTCCAGTCTCACTTAAAGAAGTCTGTGCACCATAGAAATGGTGGTAACTC ACTCTGATTTGCCCAGTAAGAAACAGCCCTTAGTAAAAGAACAGGCTTAATGCTGCTTAG TGAAATTGTGGGGCTGGTGGTGGGAGAGGCATGCACAGGCCTCCTGGCCCCATCTCTCAT GTCCCCAACATTCTCTGATGACTGCATGGCTACTGTCCTGGTGTACCTTTGCTGGGCCCC ACAGCGTAACCCGCCACAGGACTGGCCCAAGGGCGTCTAGCACCTTGATCTGGGGCCAGC TGCACCCCTGGGTTCACTCTATGAGAATGTCCTGAGCTGGGCACCCAGTGATTGGGCACT TTCACATTACACTTCTGTAAACAGTTCACTCAAAACAGCAACCTGGGATCCCTGAGTCCC TTGCTCCCCCTTCTATCCAGGAGTCCTGTGAGGGTCATGGAACAACCACACCCCTGAGCT CCAGACTCTAGAACCCCACTCCTCCCTACCACCTCCACATGCCGCCTTCCACACCCAGCC AGACACAGCCGAAACAGAACCTCACTCTGCTTCCAGCCAATTCCTACAGTCCATGTCCCC ACCTAAAAAAAAGCACCAGCAGTCAGGGGCCGACCCCATCTACCTCTAACCCCACCCCCA CCCCCAATCCATAGATGGTGCTGCTGCTCAGCCTCAAACACATCTGGGGCTTGTCTCCTC CTGTCCATCTCCACCACCATCACTCATCTGAGCAATGCTCACCTCTCATCCTGGCCTCTT GCTTCCATGGTAGAGATCACTGGCTTCCTGCCCCAGCATCCATGTTCCTGCACCCTCGCT AACAAAATTCCGAGGTTACTTGGGTTGGCAGTGTGCCCAGCTCACTATATCTCCCAGCTT CTCTGGTGAGAGTTCTGGCCAAAAAAACTGTATGTGGAATTTATTAGATGGCAATTCCAG GAAAGCTCTTTAAAGGAGGCTGATTCAGCTAGCAATTCCCTCAGTCCTTCTCTTCCTGCT GCTGCCTGGAACTAGAATGTGATGGCTGGAGCTCTGGCAGCCATGCTGTCAACATGAAGA TAAAAGTCTCATTCTAAGAATGGCCAAGTGAAACCCACAAGAGCCTATGAGACCCTAGGC TATGAGTCTATGCAGACTTGCTAATAAAATTATTAAAATCTTTAAATTACTTGCTTGCAG ATTTTTGTTACCAACAAATACCATTCCAAACTGACACAACCTCCCTCCAGTCCACTGCCA CAAAGTAGCAGTGGCCAAAGTCATGCTCTTATCATAAATCCAGATCATATCCTTTCCCCA TGTGAAATGTTTCAACACCTTCTCATCACTCAGAATAAGGCCCACATTTTCATCATGGCC AGCAAGGCCATGGACAACCCTACTCTACCTCCATCCAACTGCTCCTCATCCACACTCCCT CCACTGCACTGTCCTGGCTACACCTGAACACACAGGGCTCGGCCCCTCTGCATGGCTGTG TAACGGCTGTCTCTCCTGCCTGTCAACACCACTTAGAACATTTCCAGATGTGTCTGTTCT GAAGTTGCCGGTCTAAATCCCACTGCACAGTCTCATTCATCTGAGAGGCTTTTCCTCTGT ATAACTGATTGGTAATTAGGAGTGGCTCCCAAAAGCTGCTCCACTTTGAGCTCCCAAACC AGTAATGGTTTCTACATAGGCTCCCAATGAAGAAGACTCAATAAATTATAGGTTCAGATC TTCTGAATTCCAGGCACATTTGCAGCTCCTTGCCATAATGGTGTCACTTTTTGTTTGCAA AACAGAAGTTGACCTACTTGGCCTACAAAGTTGTGAGAATTATCTGCTAAATCATATTAC TATATAACTAATCAATTAGCATCTGATAATAATAATGTTTATTGCTCTGACAAATACGAA TGGAGCTCCTGCTAAGCCTGGAACAAACAAGTCCTGGCCCCACAGAACCCACGCCCTGGA GTGGGGCTGCGTGGAAGCAACCAGCCCAGGGCCTGGCACCCACAAACATCCCATGCCCCT CCAGGGTCCTGCTGCCCTTGCTCTTCTCAGTCCTCATTGCATGCAATGACAGACATAAGA AAGGATGGTAACAGTGGTGACAAGCTATCCACAGTCCCTCAAGAGAAAAGCTCCCATTAA AAACCAGCTACCCCTCCTTTTGGAGCAATGATCCCCTGGCATTTTAAGGATGCGTCCTTT CTCCCGTTCCATGTGACAAACATCATACAGCCAGTGAGAGCCAGAAGTGACAACGTGGCC AGGCTGCCCCATCCCTTAAAGCAGAAGAGGACTGCACACTCGCATTGTGAGAGACTTCAC ACTGGCTCCCGCGCCACTAGAGGAGGAGGAGGAGGCAGGCCTGCGGCAGGCAGGGCCTTG GAAAGGGTTCTTGTCATGCATGCAGCAAGGACACCAGTGGCCTGGTCCATGTGCTGCAGT CCCAGCCCAGTGAAACCCAATGAACTGACATTGGCTCCTCCAAGCCACACCCAGACCCAG GTCCCAGCCAGTGCCAAGCTGTGCACAGCAAGGATAAAGCAGAAACAACCTCTCTCGTGG CATGTCCCCCAGCTGGGCAAAGGTCCATACACACAAAAGAAACAGCAATGAGCTGCCATG GGATGGGAGAAGGCGCTCTGAAGACGGATGCGGAGCCTGCAGAGGTAAGGCGTGCCAACC ACACAGGAAGCCAGCCGTGGAGACAGCCCAGGGGCAGGCGAGTGGGTATACAAACCGCTA CATCCAGACAGGGGAACGTTACTCAGCATTAAAAATAAATAAGCCATTAGGCCATGAAAA GACACAGAGGAACTTTAAAAGCTTATCATTAAAGAGAAAGAAGCCAATCTGTAGAAGTAC ATACTGCATGATCCCAACTATAGGACATTCTGGGAAAGGCAAAACCATGAAGACAGTAAA AAGATCAGTGGTTCCCAGGGGCTGGGGAGAGAGAGGGTTTTTAGGGCAGGGAAACTAGGC TGGCAGGGATACTACCACGGTGGACACATGTCAGTATGCATTTGTCCGAGCCTACAGAAT GTACAACACCAACTGGCAATCCTAATGTCCAGATACAGATGTCGGGTGATAAGGTACCTA TGTGGGTTCACCGACTGTAGCAAAGGCACCACTCTGTGGGGGGATTCTGAAAATGAGGGG GCTGTGCATGTGTGGGGAAGGAGCATATGGGAAATCTCTGTACCACCTTCTCAATTTTTC TATGAACCTAAAGTTGATCTAAAAAATAAAGTCTATTAAAATCAGTAACAACAAGGAACA GGCCTAGGAGTTCCTTGCCAGTCACAAAAGCAGCCTCTGTGAGGGTTCATGGCCTGGACA CATTAAGGAAGTAAGTGCCCACACCGGAGGGCTAGGAGCAGAGACGCAAGACCCACAAGG CCCAGTTCATTTCGGGTCAAATACCAAAGATGCTGGATCACTGTTGGAGAGATATGGTTT ACATGGGATCTAATTCCTATCTAGATCCCCCAACTGCAATCAGTCCTCTGCGTATCCCAA TAAGCATGCTGGGGTCAGGCCAGGCTAAGAGTCCAGAGCCAGGAGATGGGAGAACACAGA GATTTATTTCAACTCTCTCTGGAAACCCAATGAAATGACTCTAAAAGGATATGAACTTTA AGGATAAAAATGGAGGAGGGAGGTGACTTTGGAATCTATTAATAGGTGAGCAGTAACCAA CGGTGTGCTGGCAAGCTGTAACAACTGGCTCTCCACGGGGTGGGCAGTGGGGGTGGGCGG TGGGGTAAGGTGGGGGGTGCCCAGCTTGCAGCACACGCTGATTTCTGTGGTGTAAATGCT GCTTTCGAGCTCCCAGAATGATGCCGCTGAACTGGGGAGAGGTGCACAGCAGCACCCAGC ACATGGCACTGCCATCTCAGATACAAGAGGCGAGTAACTGCAACCACACAGATAACAGTA GAATGCACACGATACTAGAAAGGAATGAGTTCTGAGTATTTTACCTTTTTAAATATAATT TGTTTCATTTTAAGTCCACATATTTAATTTTTAACAGTGGCTGTGTTTACCACCAACCCT GTCACACACCACCAGAGCTGACTGATTTGAATTTCAGACCAGAGTTGAGCCAGGGCCTGG AAGAAGTCACAAAGAAACACAACCTGGAAAATGGAAGCAAGCTTAAAAGTAAAATGTGGT GAAAGAAATGAAAGGCTGGAAAGTAAACTAAAGAGGTTTCCTAGAAGTTACACACGTAGC AGAGATGAAAAAAAGGGGAACAGACAACTGGACGATCCATTCAGGAGTCCCACATGAACT GGCAGGAGCTCCGGGAAAAAAAATGAGGAATTATTAAAGCAGTAATAAAAAGAAAATAAC TAGAACAGAAGGACCTGAGCTTTCGGAATAACAGCGCCCAGGAGCACAGTGAATGAAAGG AACCCGCCCACACCAGACACATCATCCTGAAAGGAGGGTTACATGAGGCTTCCAGAAAGA AACAGGCCACAAAGAAATTACCTCTGAGTGCCCCACTGGAGGCAGCAAAGCAACGCCTTT GAATCCCAGGGAAGATGACTTCATACCTAGAATTCCCCATCTAGTCAAATTATCAATCAG TATGAGTGCAGTACAGAACACTGCTTCAAACCTACAAGTTCTCAAATGTTTTACCTCCCT CAGCTTCTTTCTCAGAAAGCTACTGCAGGATTTGCTCCACCAAAACAAGGGAGCTGCTTC CCAGGTCTTCTTTCTTAGGAAGCGAGTGGAGGAGAGGCAGAGAGAGCGGGGAGCTGGGGA GCAGGCAGAGGCTCCAATGGGGCGGGGCAGGAGAAGGCACAGTGGATTACTGATTGCATC TGTGGCTTTGTTCTCAGAAATGCATTTTAAGGCTCTGGCAAAGAGTCTGAAGATGAATTA GAACAGATACACAGATTAGAAAATGAAGTTATTAACCCCAGGGAAGCAAGAGTGACCCAT GAATGGAAATGTAACCAGAGTGTACTTATCACTGCCCAGTTGCATAGCCCCCATTACAAA AATTACAACTAACTCCACTGGAGGTCTGGGGGAAGAAAGAGAGGGAAAGGGAGGGGACAA GAGTCAGAGAACACAATCCTGTCTTCCATCATAACACAACATCTAAGATGGGAAAGTCAG GAAATGTAGGCATATCTAATTTGAAGGAAAATACCAAAATAGTGAAAATAGTTGAAACTC AGTGTCTCAGGGCAGCAGGGAAGGGACAAAGGGACAAGACAAGCAAGTGCTGCTTCCTCT CTCAAGTTAAAGAAGAACTACTTCACTTTAAAATTACCTGCATTAATTACTCTCATAAAA TGAATTAACCTTAAAAAGACATCCATGTTCTGGTTCCTCACAGCCTGGGGAAAGCAGCCC AGTGGATCCAGAAGCAGAAGACATGACCCCCTGAAGGGAGGCTCCCAAGGACGGGAAGAG TGAGCTGACTCTGTGCAGAGCCTGGGTCCCTAGGGCAGCCAGATCTGGGGGCTCAAACAC GCTGTAAAAATAGGATTGTTCACCGCAAAGCCGAAGTGCTGGGCAGTGGCACAGGATTTA ATGCAGAATGCCAGCACCTAATGTGGCCAGCCTCTTCCACTCCACTCCTGCCCCCTCCCT CCGATGCACCCCACCCGTCTCAGGCTGCCTTGCAGCCTTGGCACTTGCTGCTCCCTCTTC CAGACTGTTCTACCCCCAGGAGCTGCTGGTGGCTGGCTCCATCCCACAGTCACCCTTTGC CTCCCCTGACCCCCACACTCCATCCCCCTCTGTGGTATTGTTTTCATAGCACTTGGCCTA AGGACCTAAAAACGCCTCCCTGACTTAGTTGAGGTAGAACAGGAGAAACACAAACATCCC AGTGAGAAGACTAGGGCCAGACCCGGAGAGGACAAAGGTAAGGAGCCAAGAGTAGAAAGT TCCACAAAACAAAATCGCCAGTGAAGAGAGATTGAAAACAAATCTTGTAATAGTATCCAC GACCAAACCCAGGGATGGCAAAGCCATCCCCAAACGAATGTGGCTGAGAGAAGGTATTTC CAGGAGTGTCAGCAGGTGCCCAGGTGGAAGCCAGCAGGTTCTCCTGTGTGGCTTTAAATG GTTACGAAGGACTGTCAGGACTGGTGCTGTTTATGCGGTTACTCAAACTGGTTATGTTGA AAAGAAACCTTTTTCTTAATTGCTTTTACCTTGGACCAATCCAGACACTGCCATGTAGAG CTCAGCAGGGCACGGGCACCCCCACCTGGCTTCCAGGCCCTGCCCTGAGAACAATGATTG ACCACCAGGCTTCCTGGCACGGATTTATATCCAGGTCTGCAGTGTATTGATCTCATCAGC AGACACCAGATTCTCGATGGCATAAATCAGGCCCTGCTGCTCTTCTCAAATGGCCTTTAA AACAGTCCACATGAGTAGCCAAAGGTCAGGACAGACCCCATGCCACATACTGCTCCTCCC AGGGAGGGGGAGGGGGCTGCACATTTTCTTTGTGACACTGGAGGGTTTTTTTTTCCTTTT TCAACAAGAATGCATTGTTTCATATAATTTTAAAGTTGCTTTAAGCAAAGCACACACCAC AACTCACACAGATCTGCCGGCCCTGCGAGTTCTTTCAGAACAGTGGCTCCATAATCATTG ATGGGTGTTACATTAAGGACCTCACTCTAAATAGTTAAATTAAAACAAAAGGAGAAAAAG GCCATTTTGCTGGCTTTCTTCGCCATTTCTGAGAAGCAAAGGTATCCCGCTGGGAGCTGA GCTGTATGCATGTGCATTTTGCCCTGACAGTGTGAAATTGCTGCCCTTTGCATTCAGAAA GAATGACTTGACACAGGAGCCCATTAGAAAGACAGGGTTGTGAAATGTCACTCTCATTAC TTACACGTAATTGGGGCTGTTCATGAGGGTGCACGAGCCCACTTTAAATGTCAGCAGAAT GGAACTCCAAGGGGGCTCTGAGCCCCACACTCTTTTGCCTGTCAGTACTTGTCAGAAGGC AGCTCTCCCACCCCCAGGGGTCTTCAAATCAAGGCAGGAGATCACAGCAGAGAAAATGGG AGTACCCAGCAACCACTGTGCATACATGTCTGCGTGTATGTATATATATATGTGGACACA TGTACATCTGTGTGTATGCATCTGTGTATGTGCACGCATGTGCATCTGTATTTCTGTATG TGTGCACATGAACCCGCATAGATATGTGCACCTATCCATGTTTGTACATTTGTACACATC TGTACAGGTGTGTTGTGTACATGTGTATGTCTGCATGTCTGCACATGCATGTGTATGTCT GTGTGCATACATATGTACACCTGTGTGAGTGCATGTGCATCTGCTTGGATCTCTGCATGT GTATACATATGTGTATGCATGGGCATCTGTGTATGTGTGTGTATAATGTATGTGTGCACC TGTGCATGTCTGCCTGTGTACATATATCCATACATATGTATCTGTGTATGCATATACATG TATGTGTGCACAGCTATATGTGCACATACGTGCATGCATCTGTGTGCGCATCTGTGTATG TGTACGCAGACATGTATGTGCGCATCTGTGTGTGCATGTGTGTATATGTGCATCTGTGCA TGTGTCACTCTGTTGCAGAACATACATTCTGATCTAGTGTTGCATCTTAGATGTGAATAG TGACTGCTGGCAAGTGTCCTGTAAGGCAGGAACCATGAACCAAAATGCCATCTGGGGACT GTCCAGTCACCCGTGTCTCGGCTCCTTCCTGGGATCAGCTGTCTGGCAGCTAGGGTAGAT TACAGAGGGGACACCAGTCACTACCACATGGAAGGTGTCAGTGCTTCTGCCAGCAACAGG ATGCAACACTGGCATTAAAATGCCCTGGCTGGCATCCCAGGGAAACTGAAAGGGGATCTC TGGTGACAGCTGTGGACTGGCCAATCTAACATAGGCAGTCATTACCTGGACCCCTGACCT CACTGCATGCAAACTACTGCCTGGGGGAGCGTGTTCTGGCTTATTTCTTATCTCAGGGGT TTGCCCAGATGGGGCAGGTAAAGCTTAGAGTCTCTCCAGGCCCTACAACCAGGACAGTGG AGGACACGCACTCACCACATCTTCCCTCCCAGCTGGAAGCAGGCAGCCAGGTGCTGGGAA ACAGAAGACACCACAGCCCTCACCAACCATGCCCTGCCAGTACCTGGCCACCTAGTATCC CCACCCTGGGATGTCCTCTGCCCCCAGAAACCCCTCTCCCACCTCCAGTTAGGATGCTGA TGTCACTGCCTTGCAAACTGAGGATAAAATGGCCTTATCCCATCAGGAATCAGGAATGGG TTTCAGGAGCTGTCTAGGTCACAAGCATAATAAACAGTTTATTGTTCCAACTTCAGTTTT CCTAGAATTAAAATGGATCCCTGGAGACCAACACTCCAGCTCTGCAGGGACATGCCTAGC CCTGGACCTGTGTTGGGCCGGACTCACCCAGCAGGGCAGCTGCCAGGACCAGTCTACTTC ACCCTCAAGCCACATCCCTGCAGGGGCAAGCGAGCCACAGCCAGGATATCTCAGACATGC TCTAACCCTCACCCACTTCCCAAACCCCTGGGTGCAGCATGTACAGAATGGGAAACCCAG GGAGAGAGACAGAGGGCGGTGGGAGTGAAGAACACAGGCATCCATCTATCAGCAATGTCG GCAGGACAAGCGCTATGAGGATGCACGCAGAGTGGCGGCACGAACAGGGCCCTTCAGAGG AAGGGTGGGGACCCCTCTAAGCAGCAGCCAGCATGGTAGAGATGCAGACTGTCATGCCAT TTGTGTGACATCACTCTACTCTTCAGACTTGGATACAGACAATACTGTCTTTTCTGGAGG GTGTGTGGTGTGTGCATGCATCCTTGGGCCCAAGCAGGTTAGTGCTAGCAAAAATAATCA TCTTCCACTGGCCTAATGTTGACCTGCTGCCATCTCTAAGGGGGCCAACGGTCTCCCTAC TGGACACTGGCTCCCAGGCACAGTGTGGGGTTGTTCTGGGAAGTGGCTGGCCAGCCCCTC AGGGAGGACTGTGTTAACCCTGCGGCCCTAAAGGGATGCCTGGTGTCATGTCTTTCAAAG GTGATACTATGGTCTGAATGTCTGGATTACCCCCAAATTCAGATGTTGAAATCCTAACCA CCAATGTGATGGTTTCTGGAGAGGGAGCCTTTGGGAGGTGACTGGGTCAGGAGGGCAGAG TCTTCATGGAAGTAGTGCCCCTATAAAAGGAGTCCCAGAGAGCTCCCTCACCCCTCAACC ATGTGAGAAGACGCTGTCTATGAACCAGGAGGAGGGCCTTCACCAGACACCAAATCTGCC AGCGCCTTGATCTTCGACTTCCCAGCCTCCGGAATGGATAAATAAATGTCTGTTTTTATG TCACCCAGTCTATGACATTTTGTTTGAGCAGCCTGAGCTGACTGAGACAGTGGCAATTCA GGGGCTGCTGGCACCCAGCAGAGCTCAGCACCGGACAGAACCCAGCCAGCAGAGATGCTT CCAGAATGCCAAAGGTCGGTCACCATTTACACTGGTAGCGCCTTTGATATGACACTAAAA CTGGTGCTTCGGTCCCCCAGAGCTTGGCTTGCAGGGAGGGCAAAATTACATAAAAGACAT TATATAGAAAAGTTTTGCTTTAAGTGGACTTTATTTGTATTCTTAATTTTCCACCTCTTA TAAAACTGTCCTACCTTCAAAAATAATTCCAAGGGTGCTTAACTCCACAAACCAAATGTA AATTAAAATAAAATACCCATTATTGTCCACAAAGCAAGCTGAAATTTAAAAGTCTGCTGC TAGTTAGTGCTGGGAAGGTGTGGGGTAAAGGACTTCTGGGTACAATTCTGAACTATCCAG ATGTCTGCACACTCTGATCCCCTGGCAACTCTTGGGCAGCAAACTATGTGTGCACAGCTA CAGGCGTGCAAAGCGACACGTGGGAAGACCACCCTGCCATGACGTGACAGTAAAATGTGC AACCAAAGGGGATGCTCCTCAATGAGGGGCTGGTTAACAGTCAGGCAAGGAAGACAACAC CATTACAAAGACTAAAGCTGGTCTACACGAACTGCCTGTGAGCCCATCACACCGAAGACA TGTGTAGAGCAACAACACGCGAGGCGCGACCCACCTGTGTCAACAGAGGATGCGTCAGTC TACACACAACACATACACACACAGCCACGGACACACAGGGACATGCACAAACACCAGGCA CAGACTCACAAGAACATACACTCCTACACACAGGGACACACAGATACCAGACACAAATGC ACACACATGAACGTGGACAGACAGCCAACTGTTAACAGTGGTCGCTTATAAGGAGGAGGA GGAGGAGAACAACCAGGAACTCAAGTTTTCTTTGTTTTTTAAAAAATGAATCATACTTTT ATATTGCTTCTGTAAAAAAATTTAATTCATGAAGAGATTATGTTTCACCCATGCTACACC CAAGTCAGTAGACCAAAAATTGAAACCCACCACATTAGTGTATGGAGCTGTGCATAATGC GATTTTTCACATGCTAATCCATTTCTTGGTTTAGGTGACTATTTCTTGCCATACCTTTGA CCTTTTTTTTATTTACATAAAAAAATGAGAAGTGGCTTCCTTTCCCCATATATACTTCGT GCTTTTTGTGACAGCAAAGTAAAAAATAACAGAAGGAGCCAGTCCTCCTGGGCTCTCACA ATGGAATTCTCTTACTGCTTAATACAGCACAGAATGGATAAAATTGTCCCTGCTTTCAAT TACCTTATAACTAAAGATTCCAAAATATTTTTTATGAAGAGACTGACAAAAAACAAAACT CAAAGACAAATGACTTAAGGGAGGAAAAAGAAACCAGCAAAAAATACTTGTAAGACAAGT GCCAATTCCTAATAAATAAAGTGATTTAACAAATGTAAGAAAACAGAGCTCCCACCCCAA TGGACCAGATAATATATCTAGCCAATAAGCACAGAAAGTGCTGTCTCCCTGGCAGTGATG CTGTGCTAATTAAAGCCGCCCTATCTAATTGGCAAGATGTGCTCTCATCACGGTCCCATG CATAGGAACCATGAAGGTCTAAGCTGGCAGCAGGACTCTTTAAAAGCCAGCAGAATAAAA AACCTTGTGGGGGCTCATTCATGATACTTGAGTAATATGAAAATGATGAAGGAAAGATGG GGTTTGACTTTTGTTTTCACAAATTAAGCTGGTTATTTCCTTCTCCTCTGAAACTGAAAA TGCATGGCTTGGAACGGACCAAAATTAAGATTAAACACAAAATGGCCCAAATCTGAGGAG GGTGACCTGGAGAGCCCTCTTATTACACCACACCTTACCAGCCACCTTCCTGCACCCTCC AAAAGAAGAGAGTAAGCTTTCTGGTGCAGGCACCAGGGGCCATCAGCCGCGGAGCTGCCA CAATCCCAAGACCCAGTGGGAGGAGAGGCCGAGAGAGCAGGGAAGAATAGGGGGAGCTGG GACAAGCAGTGGCAGAGCAAGAACAGAGACAGACAATCACTGTGGGTGCCCAGCACCCAC CTCCCCATGCCGGGCCCAAGGGATGGCAGCCAAGTCTGAAGCTTTGCCCCACAGGATATC AGGGACCAAGGGACCAAGCAACCAACCACCTGCCAGATCCAACTGAGGCCTCTACACATT ATCAACTCTGCTCAACTGAAATTACAGATCATGAATAAAGTGGTTTTACCTGTATCTTAT GCCTCTTGAAACTTTCCAGTCATTTCTAGAAAGACGTCTTCAGAAATCTTTGCTGTGAAA ATAATGGGAAACAAGGCTATTTAAGCCCTTAAACTGTGCATCCACTTAAACTCAGCAACA CTCCTAGAAAGGCACTGAAAACAAATTATTGTGAGTTTAAACCTTCTAGACTTCCTTAGA CGCAGGATCAGCTTGGCTTGCATGTGCTGGGGAAGACAGCACTGGGGCAGACAGGAGGGA GGAGCTGTGCAACCACCCACCCACGAACAGAGGGGAAGGGCAGCCCAGCCCGTTACCTGG TGCTAGAGATGAGCCCCAGGACCCGACCAGGTGTACTTTCTTGCACAATAAGCCATTCCA GTTAGCAGAGTCTGTGAACCAAAAAAGTACTATCTAATTGTCTATTAGCTCCAGATATGT ATCCTTTAAAATTCATCTTCATGAGGCAAAGAAGGAAAAAGCAGAAACACATATGGCATA ATTACAAGCACTAAAGAGCTGTTCATCTTCCTTTATTTTTGGATGGCTGGTTTTCAGCCA AACAGAACGGTGTCCACCGTGGTGTGGCAAGGTTCCATAGCATGGCTGTCACTCCTTTGC AGTGTGGGAGATCAGTCTCAAGACAGGGATCGTGGGGTGCAGTAGCAGCACCAACAATTA GATCAAGAGAATCAGAATCGCAAAACCAGAGCCACGTGCAGGACTGCAGACGCTCAGGAG CCGACGCTGATCCCTCCATGATTCTATTAACACAGGAGCCACGTAATTGTTAAACCTTGG AATCAGACTCCAGCATATTCTGTGGTGAGGAGGGTTTCTTTTTTGTTTGCCTTTTGCTTT CAGAGCTTATATGATCACGGCTCTTTTTTTGAAGCCAGCTGGGAAGGAGGCGGCTCTCCC TCCTCTACAGGAGCCCCCGTCCCTCCCACCCAGGCCCCTCACTGGACGGCTCCCTCCTCT ACAGACGCCCTGTACACCCCTCCCCAGGAAGCAGAACCTTAGACACGGCCATCCAGGCAC ACAACATCCGGTCCCCCCACCCCTCGGGGCCGACACATCCTCTGAACCCTGAGCAGGCAC CTGAGGTTAGCAAATGAACCGCGAGGGCAGTGATCAGAAACGATCACGATTCATCAGGCC CCACCGTAGTGGAGCTTCCAGAGACTGATACTGGGGTCTTCCCTCCAGCAGTGGATGGCT CTTACGGCCAATTTTATAAGCAAAAGTAGGTTCACATGAGCAGCTATGAGAATCCTGGAA AAGGCCACATCCACCCAGGACCTGACACCGACATTTCCTGTTGAAACTCCTGGGGCAGGG CTGAGCATTTGGGCACAACTGCTGGACAAGCAAAGAGGGAAAGTCCACGCTACTGTGGGC ACCTGCAAAGTGCCACATCACTTGTTTCCACGAGGCCTTCCTGTCACACGGGAGGGAGAG GGGACAGTGGCCGCCCAGAGACTGTGCCAAAAAACAGTTGAAGGCAACAAAGGCAGAGAT TCATACATAAATAAGAGGCTTAGGTAAATAATGTGAATATCACGGATTTTAAAACTAAAA AACTGGCCAGGCACTGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGCCGAGGCGGG TGGATCACTTGAGGTCAGGAGTTCAAGACCAGCTTGACCAACAAGGCAAAACCCCGTCTC TATCAAAAAAAAATACAAAAATTAGCTGGGTGTGGTGGTGCGCACCTGTCATCCCAGCTA CTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACTCAGGAGGTGGAGGTTGGAGTGAGCCA AGATCGCGCCATTGCACTCTGACCTGGGTGACAGAAAAAGACTCCGTCTCAAAAAAAACA AAAAAACACCTGAAAAACTTCTATTTTTTAGAAATGAAATAAGCCTTTGTCACTTTAATA AAGACCCAGAACTGCTCATCCTGTGGTTTAAGACACGTATCATATTCACGGTAATTTTGT GGCATCCAACAACAAATGTCAGCAGGTCTGGGTTCTCATCTCAATTGCCTCCAACAACTC CACCTGAACACCAGCATCCTTGTGTCCTGCCTCCCAGCTGGGGGTTCATATCTAGCCTCC AAAAACAGCTGCCAGCCCCAAGGTTCCTGAGTGGGAACACACTTCCTTTCTTAGTGAATT GCCCAGGCCCCAACCCCGCGTTGCCTTCACCCTACACATACACGGTTTGTTTCTTCTTTC TCAGCGTGCAACCCCACAGTTATGAGTTACCTGGCTTAAAAATGCAAACCCACACTTCTC ATGTAATTACTCATCATGCTGTTTTAACTCATATCTCCCAACTCCTGACAGCACAGGTAA AAAGAATCCAATGGCCTGTTCATCAAAAAGCAATGAAATTAATTAGGAGAGAGAAGCATT TCCCTCTCATGGCCTTCACATCCTCTCCTGGTGCACCCCCTCTAGTGCAGGAGAGTGTGG GGCTCCAACGCCCAGGCCTTGCGAACAGGTATTTAGTGGTCGCTGATGGCAGAAGGACAG AGCCACTGGCAGCGCCTTCATCTGGCCTCCATCCTGCAGACATGACCTCGCCTTCTGGGC GTACTCCCTAAGCAGGGACCTGGTGTTCTTCAGCACACAGAGAAGACAAGTGGGATGAAG CAAGAGCAAGGGGCTCTGCAATCAGAGGAACCTGGGTTCCAGTCCTGGCTTCTCCAAGTT GTGTGTTCCTGAGGGAAGTTACTGAGCCTCTCTGGGCCTCTGTTTCCTTATCCAAAAAGT GGGCATACTAATACTGCCTGTCTCATTTGGTTATGAGGATCCATGACTAATCAGTTAATG CTTCCTAGTGCTTTCCTAGGTGCCCGATGCTGTTTAAGCACTGGGAGGCATTAACTATCA TTCTTACCACTTGTGAAATGAAGCCAGTTATATCTGCCTAGCTAAGAAGACTCAGAGAGA TATAACAAGCAGGGTGCAGCTATTAGCACATCTAACAACCCCTACTGCCAGGGACTGTGG GCTCCACCAGCCTCCTCCTGCACACACGGGGGATCGGGGCTTCCCCAGGTCCACATAGAC TCCTGGAAGCAGGGCTTAGGAACACTGTGACAGGCAGCACTGCTGTGGCTGTGGACGGGG AGAGGGCCGTGAGCCCCTTCTGCTCAATCTCCTCATCCTGGCCCAGAAGCAGGTAAGGAA GTTCCGGAGGCAGAGAGCAATGGGGGACCTTCTGCTGAAATTGGCACTGCAGCACACACC TCGATGGGGTAGGCATGCATATTACAACACAATACCATTACACTCTGCTGAGCAGGGCAC CCATGAGAAAGGCTGGCTACAAAGTACACAGACAGGGCCCGGAGGACATGTTTCCGCACC CTGCTGGGCAACACCTGCCAAGAAGCTACATCCAGAATCTCTGATCCAACAGTCCTCTAC CAAGAATTCAGTATGGATATACCCCATGTGTGCAATATGACTGGAACGAGGCTATTCAAT AGGTAAACTCCAAAGACACCCAGAAGTCCACCAGTGTGTGTGCGTCTATGTGCATGGGTA CACACAGATACAGCATAGAACGTTTTCTATACAAATTATTGCACATTCCAGAGGATGGAA TACTATGCAACTGTTAAAAAGAATAAAGCTGCAATTGTATGAAAGGGCGCTGTTCAGTAA AAAGTAAGGTTCCCAAAAATGTGAGTAGTATGTTTCCGTCTGTGCAGGCACATGGTGTGT GACCGTGTGTGTGCGTGTGTGTGTGTGTGTGGGTGTGCACACAGGCTCATCAGAAGGATG ATTCAAGAGATCACAATTTAATCAAGAACCTGCTGGCAGCAATGCCTATAGAGAGAATTT GATCTGCAAAAGGAGTGTGCTTCATTTTTCATGATTTTGATTCTTTAGAACTATTCGAAT TCCTTCCTTAATCATGTGGTTTTCTAACTAAAATATTTTAAATCTGATATCAAAAGTAAA ATACAGTAATTGTAGAAAATTTGAAAAATTCAAGAAAGGCAAGAGAACACATTGCTGACG ATCTCTAAAAAGGTTACACAGGTTATAACGCTGGTTAAAGTAAGATCCCAGCTCGGGTGT CTCCTGTACTAACTTTACTAAGAGGAAGATTTCATCAAAATGGAAATTTTTAAGAACAGC AGACAGACATGACATACAGTTCTGGTCTTTCTGGCATTTTGGTGAATTCCTCATTCTAAG AAACTCTGACTCATTCACTCAACAGTCACTACTGGAGGGTGTGGGGTGAAGGTGAGAGTC AGATATAGACTGTAGACCCCCAGCCCCTGCTTTCTGGCTTGGGGAGGGCAGGCCACAGCA ACCGCACAGGACGGTTGGGGGGCCCTGCTGGCTCTGTAACATGGGAAGTGGGACAGGCAG GCTGGGAGCCATGCAAGAGGAGACCTGAAGTCCAAGAGAGAGGCTGGAGCCTACAGGCTG GTAGAGGAAGAGGGCCCGCGTGGGTCACGTCCAGGTCCTGTGTGTCCCTGCCCCGAGCAC CATGCGTGCGCATCCCCGTGCCGTTTATTACGTGGTGCCCTCAGCAGCCTGTCACGGCTG TGCAATATTCCATAATTAAATATCATAATGTGGGACATTCCGATCCTTTCCAACTCTCCA CTTACAATTCATTTTTCTTTAACCACCAGCAGTACCCGGCCAAGAATCTTTTCTGTCTGG AATGTTCACAGTGATGTTACAGAGGTCTAGGCACCACACAGAGGGCACTGGGAGATGGGC ACGGGGGAGATTCCATGGTTCCATCATGTCTGTCTGCTGTTCTTGAAAATCTCCATTTTG ATGAAATCTCTTAATAAAGTTAGTACAGAAGACACAAGTGCTGGGATCTTTAGTAGTCGT TACAACCTGTATAACCATTTTAGAGACTGTCAGCAATGTGTCAGCAATGTGTTCTTCTCT TGCCTTTCTTAAACAGAGGCTCAGGGCTTCTACTGATCAGGCTGACAGGTTTGCTTCCTT TAACTGGGAAATAATCACACATAACTTCCATGATTTATTTTCATTTGACTCTCTTCTAAA ACTTTCAGTTAGTTGAGCTGAAGTCATTTTTGCAAAGTAATACTATATTTGCTATAAAAT ACAAGTCACCTAGCTCAAACTTTTTTTTTTTTTTTTTAAATTGAGATGGAGTTTCACTCT TGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCAATCTCCACCTTCCGG GTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGTTGGGATTACAGGCATGTGCCACC ATGCCTGGCTAATTTTGTATTTTTCGTACACACAGGGTTTCTCCATGTTGGTCAGGCTGG TCTCAAACTCCCAACCTCGGTGATCCGTCCACCTCGGCCTCTCAAAGTGCTGGGATTATA GGCATGAGCCACTGTGTCCGGCCAGCTCAAACATTTTTTATGCTTCTTTCAAGTCTATTA GAAACCTTAATTGCTTCTTAGTTTCTCCCCCAACTATGGAGGAAGCATATTGTGATAGCT GCAGTGCCGGCTGTGAGGCCAGCTTGCCTGGTTCAGATTCCCATGCTGCCACATCCCAGC TGTGTGACCCAGAACAGGCCTCTGCCCCTTCCTATCCCTCAGATACTTCCTTAGCACCTC CCCTCCCTCTGCTACTCCCTCAGTACTTCACCTCCCCCGGCTATTACCTCAGCACCTCCC CTCCCTCAGCTACTCCCTCAGTGCCTCCCCTCCCTCCACTAATCCCTCAGCACCTCCCCT CCCTCAGCTACTCCCTCAGCACCTCCACTCCCTCAGCACCTCCCCTCCCTCAGCTATTCC CTCAGCACCTCCTCTCCCTCCACTACTCCCTCAGTACCTCCCTTCCCTCAGCTACTCCCT CAGCACCTCCACTCCCTCAGCACCTCCACCCCCTCAGCTACTTCCTCAGCACCTCCCCTC CCTCCCTACTCCCTCAGTACCTCTCCTCCCTCAGCTACTCCCTCAGCACCTCCCCTTTCT CAGCTACTCCCTCAGTACTTCACCTTCCCCAGCTACTCCCTCAGCAACTCCCCTCCCTCC ACTACTCCCTCAGCACCTCCTCCTCCCCACAGCTACTTCCCTGGGAGAGGGTAAGACACA GCCCTACCACCAGAGATGAGACTGCACAAATGAGGACTGTAAGGCATGGACGTTAAACAC AATGTTACAAACAACCAACAAAATGGCACTATCCCCACAATGGCGGCCCACACCAAGGTG CGGAAAGGTCCAATCAGAATCCCACAGAAACGAGCAGTGCAGGGGCAAATAGGTTTTCCT AGATCAACGTCAATCTCCATTAAACCATGATGGTTTACTCTGTGATTTATTCCTAAATTG AAGTTTCTTTCTAAAGCCCACGACCACAACATTAGCTTTTACTACTTACCTCAGCTCAAT GAGTCTGAAATGATTTAAATCCAAGATGCTTCCGTCCCGACTCCAAATTCCTTCGAGCTC TTTTTTTTCAGAACCTTGCACCCTTAATTCCTGAGTGTCTCCTTTCTCTGACCAGGACCC TTCTCGAACCCTACTAATTGCCTTCCTCACTGTGTCCTGCCTGGCTTTGGTCTCCTGGGC ACCCTCTTCCTGCCCTCCCCCACCTCTGCCCAATGTCCCCCACTTCCCTCACACCCACGG TTCATACCACCATCCCTCCTGTGAGGCCTCCACCTGGCTCCCGCTACCTGTAAGGGAATG ACACCACATTCTAAGAGCTCCACCTTCTTACGGCCCCTGTGCCCCCGGCCTTCAGTCCCC CTACACACAGAGGGGACTTACAAGGCATGCTTATTTCTTACAAGGCAGCTCGCATCACAC TATTCTCTTGCTCCAAAGCCTCCTGTTTCTCTCCAGGGCTTGCAGAGGCAGGTCTCAGCC CCCAATCTAGTGTCCCCAAAGGAAGCCCTACAACTTGCTAGGTGTGCATTTTCCCCTCTT TCTGTGGAACACCAAGAATACACCACCTATCTAGACCCAGCCCCCCAGATATTCTGATTT AGCAGCTCCCTAGTGAGGCCAGGGTCTGTCTGGTTTTAGAGCAGCCCATGTAACTGGCAG CCAGGACCGAGAACTGGCCTGCATCCACCAGATTTCCTGCCTTGCCCAGTGTTACCCAGG CCTTGCCACCTCCCCTAGGTATGTCCTGAGTCCATCCTTGACACCCACCCACTGAAATCC TGGCTGTCCACTGTGGCTCAGCTCGAAGGCCAGGGCAACCTCAGACCTGCCCTCTGGGAA CAGATGCCTCCCCTCAGCTGGTCTTCATTCACGGGGTCTCCTGGGGGAAAATGTAAGCAG GAAGAATAACTAACACCCGCCATAAGGCAAGGGTGAGGAAGTGACTGTTCTACTGGGTTC TGCGAGGGTCAGGCTGTGAGTCACCTGGAAGCAGCACGTGGCCCTGACATCTGGGAAGGG GCTGCTCACACCTCCCATGTTCATAGCTCCCTGGCAGGCTCCTCACTAACCCTCGTATCT GACATCTGACTGAATCCCAGTGTTCAAGAGGCCTGGGCAAGGACAGCCTACAAGCCCGCT GCTTTGACATCAGGGGCAGGAGTCCTGAAAGCCTGACCCTGTGGCCCCACTGGCTGTACA TCCACCCCCTCCCCCAGTGTGCCCCACTGGAGACAGGTTTTACAGCACTGCTGGGAAGAG GAAAAACAGGCTCAGAAAAATGCAACAACCGTCTAGAGCCACTGGGAGAGGTGAGATGCC CTCCCGGGTCCTGCAGTGACCCCAGGACCATGACTGGCACAGTGCTCTCCAGCTGTGCTG AGGCTCCACCTGCCCTGAGCCAACAGCTTCCTCCTCCAGGGACACCAGGGCAGAGACAGG CCCTTCAGAAACAATGGCTCCTTCTCTTTGCCAACTGCCAGCAGTGAAGGCATCACAGAA TCTGCCAGAACCATCCAGAACCCTGAACTGGTTCAGGACTACAGGCAGCCTGGGGAGATG CCCTGCACTCAGAGGCATCCCTAGTCCCCACCAAGTGTCCGCAGGGGGAGCGCATGCAGT TTCTCCAGGGGACTGGACCTCCTCCAGGCCGGGATCCTCCTCCCCTGCTGCCCTCAGACT CAGCCCAGCTGCAAAGGCGCCAGAGGCCTGCTCGTTCTGCCACGGTGCAGGCACGGCATG AGGGGATAGGCCCAGGAGCCTCAGGACAGGCCCCAGTCCAAGTGGGAATTTCTTTTTTAA GTCTCAAAACCACAAAATGCCACTTTCCTTGCTTTCATCTTTAGTGATTCTTTAAATATA TACACTACAATTACAAAGTTAGACCACCATGACCACAGCTCGTAACCAGAATAGAGTCAA CAGGGAACCTAGTCAACAGGAGGCTCTCCCTCACTATCCGGGCCTCCTCCCCAGGACATG GCTTTTGCCAGCCTTAGCAACAGCGTGGCAAACCCACCAGAGAACCACAAGCTCCAGCCA GAGCTCTGCGAAGGCCCCAGCTTTGCCTCACTCCAGGCGGGAAACAAAAGGATGTTCGCC ATTTCATCATCTGGGGCTGTCAGTTCCCGTCTCAGTACTGACCTTAAATGCTGTCTTACC GTCGTGCGCAGACACCAGGTGCACGCAGCCTCGACCTGATCTACCAGCCCCCAAAGCCCC TCAGAGGCCACAAGAACCTCCCTCAACCTCAGTATCAGAGGAAGCAACTTCAACTAAGCT CATAATTATTTTAAGACTCTCCTACATCTTAACCATATTCAAACCAAACCAACTCACTTC CCATCAACAGTAGACCAAGTGGTCACTGTGGGCAGGTGACAAGCATCACAGAAGTGCTAA AAATAGACAATGTGACAACCACAACACCCGGCTACGATGGTAAGGAGCAAACACTGCAGG CCACACCTGTGCCCTAGGTCTGTCCCCAGCGAGTTCCCCCTTTGCCACTAAGACAATTAC TGCCCATATGGATGGCCAGAATTTCAATCAATTTCTATTTCCAAATCACCAAATGACCCT CTAGCTGAATGTCACAAGCCCAGTATTGGGTCAGAGGTAGATACACTCTACTCTAATGAA TTATAGTCAATCCCCACGTTCAACTCACTAAATCCATCCTCCCTTGCAGTGCAAGGGAAA TGATATTTCTTCTCCTCTCTTCCAGATGCTTCCAGCCCAAGTAAGGCAGTCCCTCAATTC CCTTCCTGGGGAGTCAGAAGAGGGGGGCAGCCTAAAATGATACAGTCAGTCACTCAGGTC CATCCAACCCCAAATAGCCGTAGATGCCAGAAGAGGGTCAAGTGCATATGGACTAAGGAG GCGGTGTGACCCTGGTGAGATGCCTGTATCAGAAAACCACAGCCCCTGCCTCCCTGAGAC AGCCGGGGCCTGGGGAGTAACCCCTGCCGTCCTCTCAGTGTGAAAGGAGCCCAGGTAGGA ATTCCCCACTGAAGGAGTCAAGCAAACCCCCAATATTTCAGGATTCACTCTGCAGCACCC AAATGGGAACAGATCTCACTCACGTTTCCCTGCACTGCTAAAAGGAACCTGGTCCTATTA ACCTGGAACCCCCTCTCCACCCCCCGGTCAGCAGCACCTGCAAGTGGCATTTAGTGGGGC TGACTTCAAAGTGCCCAAGCCTACGGGGCTACGGCCCTGCAAAGTCCCATCCCGGTGTCT GTCCTTCCAGCAAGCAGCCAGCTCTACAGCATGTGGGGGTTCTCATTTTCCGAGCAGTGT GTCACCTTCCAGATGATTCAGAATGTGTGCGACGTGGCGGGTCACACGTGGGGAGGAGCT GGTGAGTCACTGTCACTCATTGCCCCCCACACAGTCACCTTCCAGGTCTGAGAGCTCCAG GAGGGGGGCTACCTGGCCATTGTTCTGTCTCTCGTAGGGCCCAGGAAGGAGGTGTGTTTC CCCTAGGGATGCACTCACCACTAGGGTGACCACCTGTGGAGGGCCCGCCTGGCCCTGAGG GGTGGACTCTGCCCTGTAGGCGTGGGTGGCTTAGGGCTGACCTGAGACGCTGGCTCCAAC ACCCAGGCCCTTCTCACCTGCGTGTGTCACTGAGGGCCTGCTGCTGTCCGTCTGACCACC GCTGACCTGTCATGGAGGGATACGGCCCCCACACTGAACAATTCCCTGGGCAGGCTCTTC CCAACCATCTCAGTGGTCACAAGTTGAGGACCACCACTGGCCACCAGCTCCAGGCGGCCC CCGCCATGGCCCATGCAGCTTCCTTCTGGGCCTCACATTCGATGCTGCCCAGCACTGCCC AAACACAGTCCCTGGCCCTGCAGGGGAACCTGAACTGGAAGGACGAGGGCAAGACCCATA TGACCTGCCAAGAGCCCAGTGCCATGCCCCAGCCACCAGAGAGGGTGCCAGGCGGCAGCA GAGGGGAGGCACACATCCTCCATTGCAGCCAGCGTGGATCTCAGGGCTACAAATAGCCAG TCACAGGAACTCAGAACCACGAGGAACCGGCCCCTTCATCACAGGCAGGAGGAGAATGAG GCACAGGCATGGAGCCTGCTCAAGGTCACGGAGCCTGCTCAAGGTCATGCAGCGCAGGCC AGCTCCCAGCCACTCTGCACACGGCCTGGCCCACTGTCTCCAAGACTGCTTTCTCCTGCA CCAGGGCAATGGCCCCCGGCCCCACCTACAGGACCATGGTGCACACGGCCAACCCACCTC CAGGGGCAGGGTGACAGACATCCCCCAGAAGAGCAAAAAACCAGATCCCAGTATGGGCTG GCCATAGGGAAATACGCAAGAAAGCAGCCACTAGGTCCCCATCTCCACCTTGTCAGCAGC CAGCGCAAAGCTTCTCTAGGGCTCTGCCCCCTGGGTCCCTCAGGGCCCCTGGACCCTGCC AACCACACCACTGCAGGCTCCGCATGACTGCTCCAGAGGTCCAGAAGACAGACAGGATGG ACCTAGGTCCCTGTGGGGGGGGTCTCCCCTTCCACGCTCACTCCTGGCCTTGGGTCACAG GCCCACTAAGCGGTTCGTCCAAGAGTGCGAAGAGTCAAGCACAGCCCCCAGCTCCTTCCC CAAATGCAGGTTACCCACGGGGCAGCCTGGGCATGGGCACTGGACAGAAGTGGCATGTAG CCTGGCTCTCCTAACCTCCCTGCCCAGTCAGCCCTCCCAGACCCACCACCAGGAGTTGTA CCAGGCCGGCGGCCACCTCGGCTGACTCTGGATGCCAAGAAGCCTCTAATCCTAGCTTCA CCCAAAGCAGACGACATCTAGGAGAGCATCGACATCCCCATCAGGGTGAGCGCCTTCTTG GGGCCAGGAGAGGGGGCTGTGAAGACAGTAATTCAGGTCACCCAGCAACACTGTCACCAT CCCTCTTTTGCAGCTAAGAAAGCAAGGCTTGGAAACTTCCGGAAGTCATATCAGTGTTGG GGGGTAGGGGGCAGTGTCTGACACTACAGGCATGGAAAGCAAAGTTCCCCGCCCTGCATC AGAGACAAACTCAGGTGGGCCAAAGCAAGTTCCTGAGCACACCTGGGCTGAGCTGTGCTC ATTCAAATCGGTTTCTTAACAGAATCTCAAGTTCATCTCAAGCTTGGAGCCTGGTGAGCA CTTCATGAAGAGCAGGTTCCTGGGTCCCAGCCGGGTGACAGTGGCCGAGGGACGTACCCG ACCTCCAGAAGCCCGGGAAGCATGCTGTTCCAGAGAAGTGCACGCTGCTAACAGCCCATT CCAGAGCGCATGGTGCAATAATTTTTTGCTAGCTTTAAAAAGCAGCACAAGAAAGAAATT ACGCGGTTTGCAAACTGAAGTCTACATGGTGGATGGAGTGGCCAGTTACGTGCTCAGAAG AATGCAGCTGTGGGTTTCTGTTTGGGGTCAAGCTTTGCCAAATAGTAGCACTCTGAAAAT GCACATAACAAGAAAACCTCATTAAAAACTCTGTAACCCTAAAACCTGTATCAAAGCCTC CAAAGCTGCTGCTTAACCCTGACGGGCAGCTCTGTGGGTGGGAGCGGTCACAAGCCTGGC TGAGGAGGACGGGCCTCAGGCTGGGATGGCAAGTCATGCCCAAAGCATCTGCAAATGACA GAAAGTTCTGGAAATATTTCACACAGGGAAGGGAATTACTGGACGGTCAGAACATACACC ACAAAATTTCAGAACTAGGAGGAAGTTTTCAGCAATACTCTCCCACTTGGGGCCAGAAAC TCCAAGCATCTGTCCCTGCTCCCCAGCAGCCAAAGAGCAAACCCTCCAGACAGCTCCCCA ACCACATACACACTGTGTCAAGGGGCCTGGACCCCACTTACTGGGTGAGTTAGATGCCCT CCAAGCTTCAGAGGGAGACAACTGACTGTGACTGCCTCTCTAGGGGTGGCTATTGTCCAG ACGCAAAACCCACCCAGGGCAGGAGCCTGCAGAGGGGCAGCAGCCAGGCTCGGAGGACAA ACAGCCAACATCTTCCCAGGCAGGGAAGAGGACCAGCCACAGTTACTGGGGAGGGGGAAA CTGGCCTCTGATGTCTACAGAGTCTAACAGGTGTATTTCCAAGGCCTCAGCAACCCCGCA AGCTCAGAGAGATGCCCTGCCCAGGGATGTTTATCTCCATGGTGCCTTATCAGTAAAAAT CTGTCATCCAAATATGCACCATCAGATGGGCCGAGCGTGGTGGCCCAAGCCTGTAATCCC AGCACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCAGGAGTTCAAGATCAGGATG GCCTACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCT CGCGCCTGTAATCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAG GCGGAGGCTGCAGTGAGCCAAGATCATGCCACTGCATTCCAGCCTGGGCGACAGAGCGAG ACTCCATCTTGAGGGAAAAATACCAAAAAACAAATAGGCACCCATCAGAAACAGGTTAAA TTAACAATAATATTATAGCATGCTATGCCGGCAGTACAATCCACACAAGTCGATGTTTAT TGACAAATACAGATAAACATTCTATTAAATGCAAAGAGGAGAAGATAAAACAGCACTTAA GTGCAAGCTTACTCATGTAAAAAACCCAGTCATAAAAGGTCACACCCAGGGAATGGCCTG ACTGGCACGTTCCAAGCTCACTCCCAGGCTGACTCCTAACCCTGGCGGCTCCTGCTCCTG CTCCTGCGGGTGAGCCACCCGGGGCACACCCAGGGCTGGCTAGAACACCACCTGCAAATG CAGGTAGAGCAACCTCCAGGAGGAGGGACACCAAAATGCCAGAACTAATTCTGGGAGGTG GAATTTTAGGGGCACTTTCAATGTCTTCTTTGAATTTTCCTGTATCTTCCAAATTTTTTT ACTGGAGGCATTTTTCAGTATTGTTCTCCCAAACAAGAGCAGTTTCCCTAGATTCTCTTT TGTTTTTTGGAGACAGGGTCTCACCCTGTCACTAAGGCTGCAATGCAACGGTGCAATCAT AGCTCACTGCAGCCTTGAGCTCCTGGGCTCAAGTGATCCTCCCACCTCAGCCTCCTGAGT AGCTAGGACTACAGGCGTGAGCCATCATGCTCAGCTATCTTTTTATTTTTTTGTAGAGAT GGGGTCTTGCTATGTTGCCCAGGCTGGCTTTGAATTCCTAGGCTCAAGTGATCCTCCCAC CTTGGCCTCCCAAAGCCCTGTGATTACAGGTGTGAGCCACTGTACCCAGCAAGATTCTCT CTTTTGATGGTTTCACCTCAGCAAAAAAGAAGGTGGCCCTAAAGCCCCCAGAGCACATTC CCGCCTCCTCAAGGACACGTTCCCAGCCCCTCCCTTGGCCAGACTGGGATCCATACAGTC AAGGCCCCAATACGAGCTCTGGTTCATCTATGCTATCCTCATCTCTCTGTGTCCATACCT CAGTGTACCTTCCCTTCTGTGCTGCTCTGCCATGACAAGCCCTGACCAGTCCATCTGTTC CCCCAGGAGAGGCATATTTACATGGCACAGGAGCCTGGTGGCCCAGCTGCACCCTCTGGG CCCACCCTTACCAGCTATGCAGCCCTGGAATGGCCACTCAACCCTCTGCCCCTTGGCTTC CATCCATAAGACAGAGTTGGCCACAAAAGGTACTTGGATTATTTATAACACTGCTTGGCA CAATAAATGTTAACCACTAATATAAGTAGTATTATATAAGTGTACTACCACAGAATGGAT TGGGTCATTTTTACTAGATAGTGGAACTGTAACCCTGACTAAGCCTGGAGATCTGGGGAC AGGACCCTGGGGAGTTGGGAGCTGAGATCTGAAAATTCAGGATGATCAGGGCGGCCACAG TAAGGTCCTAAAACTGCCTGAGGCTAGTGTGAGGGGCGCCCTCCAGCACTCTGTCGTAAG GGCAGCAATAAAACCACTGGCTGCATGGCTCTTCCTCCTCTGAGTGCCCTGTCTCTATCT CTGGTCACCAGTGCAGTGGGGCACACCCCGTGGGGATTTGCAGGCCCTCAATGATAAAAA CAGATTTGGTGCTGCAGGCAAATGATACTTAATACCCATATGAAAATGAGGTTAAAAAGC AAAAACAACCTCCCAACCGCCTCACACCAATCAGGGTGGCCACTACCAAAAAAAAAGCAA AAAACAAACAAACAAAAATGGAATACAAGTGTTGGTGAGGATGTGGAGAAGCTGGAACTC TTGCACTTTGCTGTGGGAATGCAATACAGTGTAGCCACTGTGGGAATCATGACGGTCCCT TAAAACTTTAGAATAACCATGTGTTCCTGAGATTCCACTCTGGGTATGTACACAAAGAAG TCTCAAAGAGACGTGTACACTCATATTCACGACAGCACTATTCACAAGGGCCAGAAATCT CTTCTGCAGCCAGTCATGTCCTCAAAGTGACCCCACCTTTATAAGGACAACCTGAAGGGG ACCTCTGTTACCATAGTGAGAACACAAGAGCGTCTTCGGGTGTGCACAATGGTTGGGAAC GTGGCAGAACTGGCTCTAGGACTTGCCAAGTGCTGCTGGTGCATCCTGGGCACAGGGCAA AAGCCAGCTCTTCACAGGGACTTCTCACCTCACTGTCTATAGCAGGCTGGAGCACGGATG TATGCATGCCCCTGCTATAGAGGCATGGATGTAGCAGTGACCCCCTGAGGCTGCCACGAG TCCCCCATGAGTGCAACTGCAGAGACAGCAGCCGGCAGCAGACGGACTGAGGGTGGGGCC ACCAGGGGACTTGCTCACTTCCAGGGGGGCCAGGCGGTCGGTGGGCCACTGCAGCATGGT CAGCACTGACGGAGTCCTTGATAGTGGGGAGGGGTCTCCAATCGGCAGGGAGGGCTCTCC AATCAGCAGAGAGGGGCTCCCATGACCTCTGTCCAACCAGCAGCCACTGCAGACTGTAAA GACAGCTGGTGCCACATGCTACGGCCTTCTGAGCCCACGGTATGTGTCCTAGAGAGGGAC TGTGCACAGGCACAGTAGGTCAGATGCATCCAACTCTTGGCATTTCGCTTAACCCCCTCT GGGAGGGACCTCCCACCCCTGCATGTAGCCGAGCATGGGCTTCTGATAGAAGCAATCAGG TTCTGCCCAAGTACAGGGTGGATACCACCCAGGGCAGAAGTCCAGAGGGTCACAGGGTCC GGGGGCAACAGGGAGACACAAAGCCCTCTGCTGTCCCATTACACACAAGAGCATGGCCCT AGGTGCAGATTGTCCCGGGGCTCAGACAGTATCTCTCAAAGCCTCTGGATGCTGGTACCA GCATACCCCAGTAGCTCCGCACTAAGTGTGGGTCACACTGGGCAGCTCCAGCCAGAGCGC CACCACTCCCCTCTGGACTGGGTGACATGGATGCTATGATGAGCTGCAGAAGCCCCCATG CAGACGTGGGCAGGAATCTGTGCATGACTCACACATAGCACTTGGCATGCACGGACTGCC CCGCTCTGGGGAGAGATGCTGTGACACATGGAGCACACCAGGAATGCCAAGTGACGTGGA CCACGCATACCACATTGTCTCCAGCTGTTCATGTTTTAAGACCAGCCAGACCTCAGCCCC GGAGCAGCAGTAATGTGCGACAAGGTCTACCCAGTCACCCGCTGCCAGCCAGGTGAGGCC CATCCACCTGTCTCCACGATGCATGCTGCCCCCATCCAGCACGCGTGTAGGTAGAGGAGG GAGGGGTCTCGGTCTAGGAGCCAGCCAGGACCCTAGAAACCTCTAGAAGGGAAGACAGAA CAATGGCGTTGGGCGCCTTCTCAATCTCCACTGAGACCTTTGTCAAAACGGTATGCAGGC CCTCAAATCTATTGCTTCTTTGGGTTTTCACTTTCTTTCATGAAGCTTCATGTATGTAAA AATGTTAGTCTGTCTTTTCTCCTGTTACTGTCTTTCGTCAGTTTAATTCGCAGGCCCTAG AAACAGCATCTAAGAGAGTAGAGTGAAAGTTTTTCTTCCCTCCACCACCAGCGTAGCACC TTCTCTCCTCTCTGCCCTCCTGCCTCTCTCATAAGAAAACTCTGTGATTACATTTAGGGA TCACCCTGGAAAATCCAGGAGAATTTTCCTATCTCAAGGTTCTTAAGTGAATCCTATCTG CAAAATCTCTTTACCATGTAAGGAAACATTCACAGGTTCCAGGGATGAGGGATGCCCCAA GGTACTAGGGCATCATTCATCCTCCTGCAGACCCCTGGCATGTGCAGCCATGGACCTTTG AGTGAAGTCTCCAGGGCCCTGTCAGGGAATGTAGAGGGGAGGCAGGGCAGCTGGGCCAGG CCCTGTCTAAAGGGGCCACTGCACCTCCCAGCCTTCTACAACATGGCCTAGTGTGGGCAA TAGTTCTTGATTTTTTTCTCCTGAAAGAAAAAAACCTGAATTTTTAGGTGAAGCCTTTGA ATGCTGCAACATAATTAATCCATATATTTTTAATACTGGGAAGTCCCAACCAAACACATC TGAGGGCTGAGTTGCTGGTCTAAGAGCTCAGAGTCTACCTGGGCATGGGGGAAGGGGCCG GCCAAGGCGGGGAGTGCACGGGGGCTGCACATCCCCCAGGGCATGTGGAGGACAGAAATC CCCACTAAGAGAGTCATGATAAAGGCAGTCATAAGGTAATATTAATTTTAAGAATGCTGG TTGAGTAAACATGCAAATGATCATTAACAGGACCTGGAAAATAACCAGAAAACCAGTACA TTCCATGGGAATCTTGACTTGATGAGCCATTCAGATGCAAATTTTACCCCAATTCTGGAA GGATTACAAGCATCCCCATTCACAGCCCCCATTCCTATGTAAATTCTAGTCCGAGGACTG GCCCTCCAGTTCCCAGCCTTCTGGCTGCTTTGCCCTGTTTCTTTCCTTTAGGCTCCTAAG CAAGAGCTGTGGAGTTTCTGGTTTGTTTCTGGCCCCTCCTCCTTTCCCCAACTCACAGAG ATGGCAGACTCCCAGGGCTCTCTGACTTTCACACACCTGGACCATACTAGACACAGTGCC GGGCATGTACTTTGATTTACAGAACCCAGGGACAAACAAGGCCACCCAGGTCTCTGTGTC AGCAAAGATCCTGAACATCAGCCACACCCACGGCTTTATGCAGAGCAAGTCCTACAGGCT CCACCTACGCCCCACCCGGCCCCGACCAGCCTGCTGCCTGCTCCTGGACAACCTGGTCTG GGTGCACCCCTCCCAGGGCCACGCCCACAGGTTGCATGTCCGGCCTTTCCTTACAAAGGC TGTGCAAAACAGAGAAACTTCGAGATAAATGAAACTTAAATAAAGGAAGGGCATGAACAC TGCCCAGTGTCCATATCTGCTGTGCCGCATCCCAATGCATGCTGAATTGGCTGCCCAGTA AGAGAAAGCAGGGATAGCCTAGGCCAAGGAAGCGCCCCCGCTGCCCCCCACCCCCAAATC ACAGCCTCAGCCTTGGCTGCTCTCTGGCCAGCTACAGAATGACGGACATCTCAGACAACA TCCTGCACTTCTGTTGTCTTCAAAGCACAGAAGTGCAAAGCTCTGGAGTGAAGCCTGTAA GGTCCACTCAAGTGTGTTTTTCCTCTGGTTGTCCAGAAGGGCAGCTGGTCATTTGGTCCC CTCACATTAGAAGGAAGCCCACTTACTCAGCTCATTCTCACTCAACCCCAGTGAGGGGTG AGAAATGGGAACACAAGACCATTTACCAAATGACAAAGAAAACCCAAGCCCCTGACCCTG CCCAGCTGGCCTCACCTTTCCAGGGGCCATGCTCCTGACCCCACGCTGGTCAGCGTGTCC TCAGCCACCAGGGAGGATGGATACTCAGGACACCATCTGGCCCCGCCGCCCCATCCTCAC GCAGGGCCTCTGCTCGCCTGGGACGTCTGTCCTGACTGCAGGGGTTTCAAGGGCTCTGTT ATTAGTTGGGGCTCAGGCCAGGACTGCTCCAGCCACAACAAGGCACCCTTCAGCGCAGGG ACAAGGTCCCGTGGTGAGCCTTCTCCGCAGGCTGTGGAACAACCCTGTCCCATTCTCTTC CTTTTAAACAGCGGGGCTGTTCAGCGATGTGGGCCTGATTGTTTTCCTGTGTGGGCTAAT TCAGGGGCTCGTGGGGCAGGGCCCAGTCCCAAGGCTGAGGAAGGAGGAGAAAGGCTGCCT TAGAGGAGGGTGTGGGGGGTTGCGGCCCAGCACCCAAGCCATGCACACCATTGTCCACCC ATGGAGCAGCAGGTCGCCTGGCGAGGGCAAGCTCCTGGGTGCCTGAGGACCCTGCAGGCC TGGCCACTACTTCAGTCATCTGGGGGCTCCATGGCAGGATGGGTGAGCTGCCTAAGGCCA CGGGACAATGGGGCTAGAGGTGAAGTCCCGAGGAAGCAGATGTAGCCCTGGGCAAGTCAC TCTGGCCCTCTGAGCTCTCATGTCCAGCCTTGGACTCAGGAATCACGAAGACAGCTCAGT CAAGAGGTAGCAATGAGGGCAAACTTGGGAGGTGAGCATGCACAGAGCTGCTGGACAGTG CTGCAGCGAGATGGCCTGCTCCCAGCTGGGCAGACGACCCTAAAACAGGAAGCACGTGGC CTCTTTTGTTAGGGGCTGCAGGGCCCTGGCTGCTCTGCGGGCCAGCATGCCCACCCCCAT GAGTGGCCTGATCCTAGTGGGCATTGCACAGTGCAATGAAGTGTGGCTCGTGCAGCTCTG GCAGTTTTTATTTTTCTGCAGGCCAGGTTTTCCTCCCACAGCGGCAGGCACCTGCCCTCA GCCTGTAAGGAAGCGCGATGCAGTGAGTATTGCCCAATCTTGGTCGCCCACACTTGGTCT TGAATAAGCAAACAACCACAGGACAAGCAGCAGGGCAGGTGTGAAGCTCGCCCTGAGTCT CTGACACTGCAGGTGTGGCCTCCAGATCCCAGCCTCTGCACCCACCCCCACCCAGCACCA ACCCTAGCAGGCGGCAGCGACAGGCACTCCCACTGCTGCGGTGCGCCCTGAGAGGGGAGG GCACAGGCCTGGCGCATGACTGGGCTCAGTGACACGGGCACCTGCCCATGTGTGCCAGCG GCAAGGGGCACAGGTTCCCGGTGCTGCCTCTGGTCAAGGGGTCCCAGGGAGGGAGGTCTG GCTGATGTGTCCAGGTGCTAAAGGAAGGTAGCAACGTGACTTGAGCAGGCACAGGTGACA GCCACACAAATGAGGTCTCTGAGCCTCGGAGATGAACAAGACAGGGACACTGTATAAAAG ATGTGGTGCTCTGCCCTGGTCCGCAGCTCGGGACATAGCCAGGACAGGGACATGCTTGAA CCCAGATACCAAGTCTAAAATTCCTTAAATTGAGCAACTCAGTCCCAAGGATGAGCCATC CAACCTGCTAACATGCACAGTGCCATCTGGCACCAGGCTCTGCGCCCTTCTCGCTGGAAG ATTTCTAATAACCTACAGGGGTAGGGATAGAAGGGCAGGGCCATCTCAGCAAGATGCAGA GAGGAACCAGAGGACACTTTACCCAGTAGGGCACCCAGATGCTGTGGAGGGAGCAGCCTC CCTGGGGGCTGAGTGTGGAAGAGGGAAGAGGGAAGCAACAAAGGTGCACTGTAGAGAATA CTCAAGCCAAGCGCCCTGCTTCTCTCCTGGGAGCCTTTTGTGGCCATGAAGGCAAGTTTT AAGTTTGGAGATGAGAAACTGGAGACCCAGGAAGGGTGAAGAGTGAAGGGCTGGGGGCCT CAGCTGGTGCTGGACTTGTGCTCATGTGGATGCCACACTCAGGCTGGCCTGGAGAGAGCT TTCAGGGTGGAGCACCTCCCATGGCAGCTCGTGATGGCTGCATCACAGAATGCAACAAGA AGGTGAGCAGGACGACATTCACCGCGGGAGCCTGGTGACTGCAACTCCTGCTCACGACAG AGCTGGGGTCATGCAATTAGATAAAATATTAATCCAGTACATCACGGGCTGAAAGCTATG CCAGTCAAACCCACATTATGAAGCACTTTATTCTGTCGTTCCTGAGACAAACAACATTTC TAGTGTTAGGGATATTTGAGGCAAAAAATCGAAGTATTCTTTATGTTCTTTGACTAGAAT CAAATACAATGTATGTTTTTTCTTTTCTTTTTTTTTTAAGACGGAGTCTCGCTCTGTCGC CCAGGCTGGAATGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCTGCCTCCCAGGTTCAC GCCATTCTCCTGCCTCAGTCTCCTGAGTAGCTGGGACTACAGGCGCATACCATCACGCCC GGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTC AGTCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGTATTATAGGTGT GAGCCACCGCACCGGGCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAACATGG AGTCTCGCTCTATCGCCCAGGCTGGAATGCAATGGCTTGATCTCCGCTCACTGCAACCTC TGCCTCCCGGATTCCAGCGATCCTCCTGCCTCCGCCTCCTGAGTAGCTGGGATTACAGGC ACCCACCACTACGCCCGGCTAATTTTTGTATTTTTATTAGAGACATGTTTCCACCATGTT GGCCAGGCTGGTCTCAAACTCCTAACCTCATGATCCGCCCACCTTGGCTTCCCAAAGTGC TGGGATTACAGGCATGAGCCACCGTACCCGGCACAATGTATGTATTTTAAGAACTTCTAT AAACTCTACAGTATGTTTCACAATTTTCAGACATGTTTATAGATTCAGAATATATGAGTT ACCTGGCTTAACGAATAGGGTTTCTTAGAATCCTCTAAGATCTAGTGGCTGAGTGGAGAC CACTCTGGCCTGTAAACTGTCCAGGAAAGTAATGAGCCCTGAAGGTAATTGTCTTAAAGC AATGGTAATATTAAGAGAAACACTCAAACTGGAAAGAAGCATTTCTTCTATGATTAAAGA TTTCACAAAAAATTAAGGTTTTTAATTATGCAAAGAAGCTAATGGTTTCAAACACCTGCA TTCACCACCCACACGAACAATGTGGTGCAGCATTTATTCCATTTCCATCTAAAAGGTGTC AGCTCAGCCGGCGGCTGACTGGTCTAAAGATCATCGCAGCTGGCCGGACCCCAGAGTGCA CTGACAGGTCAATCTGATTTACAAAAAAAGCAAGAGTAAGTGTCTATTTTTAAAAGCCTA TTTACAGGTTATTTTCTCTTTACAAAAAAAGTCAGTGATGCCCCCACTTCACGAATTTTA GCTGAATGGAAACCGGCCGACCCACGATCAAGCTCACCGCATCTTAGTGTCAATTTAAGC ATTCACTTACTTTAGCCCACAAACATGCCATATAGTCATTCTACATTGGCACACTGCCCC TCAATCACCCTCACCACAGCCCAAAAGTGGACACACGTGCTGGGTCAGGAGCCGTGTCCA GGACACATGGAGACCTGCCTGCTCTTAGTCCCACCAAGGGCAGTCCACAGAGAATGGAGC CACGATAAGAGGCCTGGTGTCCTCCCTGTGAGCCTGACCCTCACCCTGGGAGCCACGCAG GCTGTGGCATCTCCATCCACACCCACCCGGGACGAGCCCTGGAGTGGTGCTGGCTCCTCT GCCCCACAGACCCAGTTGAGGCTCCCTCCCCGCCCCTGCCAGGAAGCAGTGACCACAACG CCTTCCCTCCCATTCCTCTCCAGCCCCTGTGCCTTCTCCCACCCACGCTTTCACCCACCC CCATGGTATAGCTACATGAGTATCTCGAAACTCCAAATCTGGTCTTGACATGCCTCTGCC AAAAAGCCTTCAACAGCTCTTTGCTGCCTTTTGCTTAAAATCCCAACCCTTTACCCTCAC AATGCTGTCTGATCCACCTCCCACCCGCACCCATCACCCTGGCCCCTGAGCCCTACCCTC CGCTTGCCCTCCACACTCAGCCCCCAAGGAGGCTGCACCCTCCACAGCAGCAGGGCCCTT CTGGGTAAAGCGTCCCCTGGTCTCCTGGAAAAAAAGGAGGCTGCTTCCTCCTCTGAGCTC CCCGGCACCTCGTGCAAGACTTATTCATGTTCCTCTGCAAACATTTCCTAACTACTTGCT ACGTGCCACATGCCGTGCTAAGTGCCAGCAGAGCAAAGTGGGGCTGACTCCACCCTACGG AACCCTTCCAGTGGGCAAGACATCAATGTCCCACAGCATGTGCTTGCGTGTGTGTGATGA CACACTGTGACAAGTCCTGAGTAGGAACACACAGGGTGCCAAGAGAACTACAGGAGACAA GCTGGCCTGGTGAGGAGGCTAAGTTGGACCTGAAGGGTGAGGTGTCAGAAATGCACAAGT ACACTTTAACTGGACTACTGCAGCAAATTTCCACCCAAGAGGGCAAAACAGCATGCAACT TGACTGATCAGAGCTCCTGAAAGTTGTTTGACCTGCTCACCCAGGGAGTCCTTCTAAGAA CAACAAGCCACTCTCCTGGGCAAGCTGCTCCCTCAGCAAACCACCATCAGGCTGGCTTCA CGCCCTCTGCTGCGTCCACTGATCTTAAAGTCTTATTACACATTGTAAACATGTCCCAGT CCAAATCAGACCAGCCACCCACATTGAAAGATCTGCCTTAAACCAAACTCCCAGACCTTA CGAATACCAACCCTTGGCCTCCGCTTCCACACACGCGCAGGACTCGGCCGGGCGGCACTG TTCCTCCCAGCAGCGGGCAATTTCCACAGCTTCGCGTGGTGGACGGGCCATCAGGGAGGA CTCTTCAGGAATTTGGCACCAACAACATTAGCTTTCCAGGCAGACAGAACAGCAGGCAAG ACAGAGCCCAATGTGTCTGGGATCAGAAGGAAAGGGGATGTGGCCGAGGTGATGATGGCA GAGGCAACCCTGAGCTCTGGCTGGAGATGTCGGTACCGGCCAGGCCCCCATTCCCACATC ATGGGCCACCCCCACATCACTGTGTCAGGATCAGAATGCCCCAGACCATGGGAAGGAAGT GAGGGCAGCCTGGAAGCAGCAGGCAGGGAGGGGACCAATTCCCCACCACCCCATGGCTCC TCCTCAGGGCTCCTGGGACCTGCCTGGAGGCTGTGGCTGCTTTGTCCCTGGGTGTCCTCA GTACCCTCTTTGTCATTTCAGCCCCAATACCTGTCTAACCACTCTGCGTCCAGCTTTCCT GCCTGGGCCCTAACCCCCCTCCCACACTCCCATCCCAGCCCACACTGTTAAACTTCAGCT TCTGATCTAAGTGAAAGGGAAGTCCAGCAACTCCAGGCCCCACCGTGTGGACAGAGGGCT AGAGGCTGGCAAGAGGGGCTCATGGCCACGCCCATGTTTGACAGTCCCTCACCAGGCACC CATCCCCATGGCTGTGTTTACACATTTCTCTTCCCCATTGGACTGTAAGGCTCTGTTATT TAACGTGCCTGAAATCTTGCACAGTTCATGGATGTGTAGACCAGCAATGGCCAGGCTGGT GAGTTCAGCATGTTCCTGATCACCCCTCCCCATCATCAGCACCCAGTGAGCTGGGGCTGT TTCCTTCCCTTTTCCCCTGGCCCAGGACACATCTTCAGGCCAGAGACATGGTTTGCTGCG CCGTACGGCCCAGGTCAAGGTCACTGGCCAAAGCACTGGGAGGGGCTCAGTGGGTCGGCT CTGGGCACCACGGCTGCCACGAGGGTGGTAGGGGCTGCTGGAGCCCCCCACTCCAGCCCC ACTGGCCCGCCTGTCAGAAGAGGAGGGAGCTACCTGCTCTTTCCAAGCTTGCCAGGCTCC AAGAGTCCTCTGTTAAACATGGCAGCTTTGCAGGAAGAATACGGACCTCATTAGTTAAAA TGCAGTGGAATAGAAAAAATTGTAAGAAAACCATGCAGCAGCAGCAACATGTCAAAAGAG TGAGATGGTCAGCAGCAAGGAGGGGAGGAGGGGTGGGCGCCATCTGAAACCATGCATAAA AATAAACCATCTGCCTGGCCGGGGTCCTCTTCCTCTACTTGCTAGAAACACAGAGTTCAA GGTAAAAATGGAAAAGACAATGAGTTTCACTTCCACAGGCCCCAACAGCTAGCAAAGAAT CAGACCCACTCACCCTGAGCTGTCAGGATACATGCAAGGGGAGGGGAGGGTTCCTGGGGT TCATAACTGCATCCGTCCCAGAGAGGGATCAGCACCAGACAGTGTCTGGCATGGCTGCAG CCCTCCCCATCCTTCTCACCATTTCCCAGCGAGGAAACACCAGACCCGGGCAGATGTGAG TCAATGCTGGGGACCCTGGTTCACGCATGTGCCGGTGTCGTCTGCAAACCTGGGCCCCGG GCCTGGGCTGGGACAAGCCTGTCATCACACAGCCTGTGAGACTTTTAAGGGCCTTCACTG GGGCTAGAGCAACCTCGGATGCCCACCAGGACCGTGCTCAGCAGCAGGAGGGCCCCCTGC ACCCCTACAGCATGCCTGCACAGCCTCTGCCTGACCTGGGACTGAAGCCTCCCAGGAGGA AGGCGGCTCTTCTCCCCAGGAGGTGACTCACAGTCCAGAGCCCAGCCCCATCAGGTCCCC TAGGGACTTCTCCACAGCTTCAAGAGTGAGACTTCCCTGTCAGTGGCGGGATTATGACCA CCCACACTACCCCCCTGGACAGAGGCCGGGTCGCGAGGTGCTCTGGAGAAGAACGGATGC CAGTGCTCAACTGGACACACACTCCAGCCACAAGCCATATGTGGGCTGAACAAGGAGCTT AAACAGGGCCACCAGGATGCCCATGGGCCCAGTCTCCAGCCACCTTCCCACGGGGCCTGG CTGCCCTGTCCACCTTCTCACTGACCTCGAAGCGGGTGTACCACGGTCCTGTTGTCCCTG CAGAGTGGAGCCTTCAGCTGTCTGACAGAAAATGAGCCCTCCCAGTAAAGCACAGCGTGG ACTCCACCCGCCCATAATAGCCACCCGGGAAGCAGGTCCGGCCAGCAGCAGCCGCCAGAG GAGGATCTGCCTGGGGTAGGCGGGTGGCGGACGGCCCTGGCCCTGCAGCGCTCAGCTGCA CCCCACCCCATGCCTGCCTCCGAGCTGGTGGCCAGGACCTGGCTGCCTCCTGTCCTGGCT GTGAGTCCTGTATGGGCTGGCACCTGAAACTCTCTACCCTCCCTCCACAGCATGGGTGGG GCTGGGGTCACCAGTGGGTAACTGCAGGCCCTGACCTCCTGGGCTCCCTGCATAGGTGTG GCCTGCCCTGCTAAAGCAGTGCCACAGAAGATGGGGCACAGAGAGCATTTGGAGACTGCG AGGTGCCAGCTGCCAGAGGTGCCTGGGCATGGGCATCCTCAGGGGCCCAGAGTCAGGCAG CCCTGGGCCAGGCACAGGCACCTAAGCTGCAGTGACACGGTCACCCCACTGCATGCCCAT GCATCCTCCCACCACGGGCAGAGTCAGGGCACTCATGCCCAAAGGAAATCCAAGCAGTGG GTGGGTCCCTGACACGAAGGGTTCTCTTTTCACTGCTCCCCCCATAATAAACCTGCTTTA CATTTATTGTCCTAGACACCTTGCCTTTTAGAAATTATACCTACCTACCATAGACATAAT TCTGCGTCCACCTGGTGGTCTCTGTTTTCCTGCTTCACCTTGGCCTCCCTCCCCACCTCC ATGGCCTCCTCCCTGGCTGCCCCTCTAGCACAGCTACAGTGTACCCACCCTTATCATGCT CTGCCCAGGAGTCATAAGGAGAAACACAGGCAAACACATACAGGCATACACAGGAGCACT CCTGCCATCACGGCTCACAAAGCACGTCATCACACACACAGCACATGAGGGGACTCCTCC CAGCTATCAGCACTTGCTCTGCAGCCGCTACTGACGGGATGTGGGCACGTGAAGAGACAA GCAGGCCAGCGAGTGGGATGGAGGATCCCCAGACGGAACCCAGTTTACATGAGACCCTAA CAGACCACAGAGCTGTCATTCAATTCATTGGTCAAAGGACGGATTATTGACTAATTAGTG CTGGCACACTGGAAGGAAACAAAATTGCCCTCCCCCACCCCAAGCATATTATTTCATGTT AAAAGCATTCTAGACACGTTCAAGAGTTTAATTCAAACACACAAAACAAGAAAACTCCTG CCAGAAAATCCTCAGACAACCCATGTAATCTTCTTAACAAACGCTGGTACCCACGAGCCC TAAGAGAAAAGAGACATATTCGACCATAAAATGAGTTAATCTGGACAGCAAATGATACAT TAATAAAAGAAACTGGCAAAGAAAAGAATTAGGAATAAACGTTTTCCAAGCAGAAGAAAG AAGATCAATATCTATAACAAATCCAGAGCTCCTACAGATTGGCAAAAGAGGGCTGAACAT CCCGACAGAACAGGGTCACAACACACAACAGGCGATTCACAGAAGATCCAAACGGCCACA GAATATCCAACAAGGATGCGACACTCACCAGGATCTGGGGTGACACCATCAAGGCCACAA AGCTGTCACTCTGCCCTTGAAGACTGACAAGTCAGTTTATAGTGTTTCATGCCACCGCCG AAAGAAGGTGCTGGAACAGGGAGCTCCCTGTGCTCACAGGGAAAGGATGAACTGTTGGAT CTTTTCAGAAACGGATCCTGCAAGATCTATTACAAGGAAGAGACACACGCTCTTTGGACC GTGAGTGCTGCTCCCTGAAACCCATGCACTGAATGACAGCTCCAGAGCATGGCCAGGGTA TTCACGGAAGCACTGTTTACACTGCCTGTATGGTTTTCAGGCAGCAGCTCTCACCAGTGA CCACAAACTGGGTGGCTTACAACAACAGAAGTGTATTCCCTCACAGTTCTGCAGGACAGA ATTCTGAGATCAGTTTCACTGACCAAAATCAGGGTGTCAGCAGGACCATGCTCGCTCTGG AGGCCCCAGGGGAGACTCCCTTCCTGGCCTCTTCCAGTTTCTGGTGGCAGCAGCGTTCCT TGCTTTGTGGTTCTTTGGTTAGTCAGGGTTCTCCAGAGAAGCAGAACCAATAGGATGTGC ACAGGGAGAGAGAGAGATTTATTATGTGCTCGGCTCACGTGATTATGGATCTGTCATCCA CAAGCTGGAGACCCTGTGAAGCTTCCATTCACAGGCAGTCAGACAGCCGAAGTCCCCTCT GACTTGGGAAGCCGGGTCTTTTTGTTCTATTAAGGCCTTCGACAGATTGGGTGAGGCCAA CTCACTCTGGGGAGGGCCACCTCCTACCCCACCTTCTACTTTGCACGCCATACCCAGGCC TCAGGCGGGTTCCCTACCCATGCTCCCAGCCTCTGCGTCCACCTCAGAGGTCTCTGCAGG CTCAGCTGGAGGTGCCATGCAGGACAAGCACTGCACCCCCAGCAGGAGATGAGACGAGAC CCTCATGTCCCGGACCCCCTCCCTTCCAGGCCCTGCCATGTGTTCTATCCCTGCAGGTCT GTCCATCCTGCTTCCCAGGCAACAGCTTTCCTTAGTCTACCGATTCTCATGTCAACCTCA CCCAGGAACACCCACACAGACACCCAGAATAGCACCTGACCACTTATCTGGGCACCCGAG GCCCAGCCCAATTGGCAGATAAAATCCACCCCACACCCACCACTACTCTAGCCTCTGTGC CCTCTGTGCCCGATCTCCCTCTGCTGCCTCTGAGAAGAACACTTGTGAGTGCATTTGGGG CCCACCAGATAGTCCAGAATCATCTCCCCACCTCAAGATCCTCAACTTAGTCCCAGCTGC AGACTCTAACTCTATATAAAGTCACCCTCTCAGGCTCCAAGGGTTAGAACCTGGTATTTT CGGGGGCCATCATTTGGCCTACCACAAGGGGCAAAACCAAAGAACAAAAAAAACCCTGAG ACTGACTGAGTGGCTCTGAACAGGGCCTGCTCCAAGGCCATGACCCCACCCAGCCCAACA TGGGCTAAAGAAAACAAGAAACACCATCCCGTCTCCATGATAAGCACCACGGGGCCTCTC TCGGGCCACCAAGGAGGGCAGAGAGGGGAGGCTGCCTCCCAGGACTTCTCCAGGGCTCCG AGGCTCCCTGCACAAAGGATCAGCCGCTTCCCACTTCCCCTCAGCAGGGGTGTGGGCCAT CCTGGACCCTGGTGGCCACACCTTCTAAAACAAGGCAGCAGCAGGAGGAGACTGAGGCAT GAAAGGGGGGTTATGTGCCAGGCACACTGGCGGGGGAGGACAGTGACTCCCCTCAGGACG TGCCTTCCACTCCCCACACCACGCTGCACCCAGGCCTCAGGCGGGCTCCCTGCCCACACT GTGTCCAGCTCGGAGGACTCGAAGTCTCAGCTGGGCGTGCCCCTGTGGGATAGGTGCTGC CCCCAAAGACTGCAGGAGATAAGAGGAGACCCTCAATTCTCCAGATGCCTTCCCTTCCAA ATCCTGCCATGTGTCCTATCCTTGTGGATCTGTCCATCTCATCTCCCAGGCCCAGACCAT CTCTCCCACCGCAGCCCAGCAGCCAGTCCGAACCCCGACCCTCCCTCGCCCGCTGCCTAT CGGTCCTTCCAATCTCGATGGAGGCACCCAAAAGTTTGTCTCTCCTTGTGACCCTTGCAG GCCAGCATGGAACAGGAGCAGGTTCAGACATGTCTCTACCTGACAGCAAAGGAGCAAGGG CATTCTGAGGGGGCCTGCCCTGGGAGACCTCCATATCCCCGGCTCCAGTCAGGACTAACC CTTGGGCTAGTCCTCAGATGTTTCCTCAACTCCAGGCTTAGGTACCCCACAGCCTCCTCC CCACTAATAAGCACCTCAAGCTTCCTGTGTCCCCAAACCACGCTCCTCACCTCCCCAAAG CTGAGATGCCTCCGAGACAGCCCAGGTGGAAGCCCACTTGGAGCCTAAGTCTTTCCAATG GCTCAGGCCAAAATCCAGGGTGTTCTGTGCTCCCCGACCCCCACCATGACCCACCCCAGA TCCAAGCTGGCAGCAAGTCCTCTGGGTCCACCTTCAAATAAGCGCTGAAGGGAGCCACTC CTCATCGACATTGCTGCACCGTGCCCACACCAGCACCGCTCTCCCAGACCACCTCACAGC CTAACCGGGTGCCCGACACCCCCACAATGGCCCATTTTCCCCAGAAGCCAGGGGTCTTCC CCAACCCCTCAAACTCCCCCACCCACCACCTCCTCTCCTACCCCTACCCTTCCTGACTCT GCCTCAGCCCACTGCCCCCCACCACCACTTCAGTGCTCCCTGGACACCCAAGACTTGCTC CTATCTGTCTCAGGGCCTTTGCTCCTTTGTTCCCCATGCATACGGTGCTCCTCCCCAGGC ACAGGCATGGCGCCAGCCTTGGCTCCATCAATCAGCCCAGCTCCCCTTGTAGAACCCGTC TCATCTCCTTCTCTGCTTTATGTATTTATTTATTTGTATTTTATTTTTATGTATTTATTT GCATAGGGTCTTGCTCTGTCACCCACGCTGGGGTACAAGCTCACTGCAGCCTTGAATACC TGGCCTTAAGTCACACTCCCACCTCAGCCTCCTGAGCAGCTGGGACTACAGGTGCATTTC ACCATGCCTGGCTGATTTTCTATATTTTTATAGAGATGAGGGTCTCACTATGTTGCCCAG GCTGGTCTCAAACTCCTGGCCTCAAGTGATCCTCCCATCTCGGCCTATCAAAGTGCTGGG ATTTACAAGAGTAAGCCATTGCCCCTGGCATCTTTTTCCGCTTTATTTCTCCCCCTTGTA ACTCCAGTCATACCTGACCTATTGATCTCCTTTGGGGTCTGTCTACCCCAACAGTAAATA CTATTTCCTCTGCTGATGCCCCACTGCCCAGGCATAAGGGACCCAGGGCAGGAGCTCAGT GAACTGTGCATGACAGGCCATGGAGGACCCACCCTCCCCTGGGCGATGTGGGATAGAGAC AGGGAGGCAAGGTATGCCTACCCAGACCAGCCGGGCTGCCCCAGCACCAGGAACAGGCTG CCGTGGGGGCCACAGCCCGCCTACACTCTGAGGAACAGCGATCCACACAACGGCAGCAGA GAAGGCGTAAAACCACGAGGCCTCTGCACATAGATGAGAATGTGTCAGACGCACCCAGAA AGCTATTCAATGAAAGGGCTTGTTTCACGGGCTTCACTGGCGGGCATGACAGCATTGCCC ACATGTTCACTCTCTGCAAAGAAAAATGGGCCATTTTGAGGGATATAAATAGCCCGGCCA GATGTGGAAGTGCCTGAGGGGCTTTTCCCAGGACTCCAGCGTGTGTCCTGCAGCTGCATA GATAGCAGCCCCTCAGTGGGACCCCAGGGGTGGCCAAAGCAAGTGAAGGTCAGGGCCTGA AAGGGTTACGTGGGGACCCTCCTCCCACGGGAAGGCAGGATGGGGCTCATCACAAACCAT CACTGACCTGCAGGCTGAGCACGCCCATTGATGCATTCAGGGTACAGCTGGGACATGGAA AATCAGTGGCAAATACACTGTGTAAGTCTTACCCACAGAAAACAAGGGAGACACAAGCCC GGATAGCACGGGGCCTTTTGGGGAGGGGTATGCTCACTGAAAGCACAGGCCCGGGAGCCC GGCAGATGTACAATCTCAGTGGTGAAACCTGGCTATTTGCTAAGGCCCAGCAGGCTATTT TGTAATTGTCTGCAAAAATGCAAAATAATAGCACTTAAAGCTGGCTAAAAACACTCTCAA AGCCTGATACGGTTGTTACAAGTCACTAGCTCCCAACTACAGAGGCGGGGCCTGAGCAGG AGAGGAAGTCAAATCCAAGGGCACCAAAGAGCAGTTTAGATCCTACACCTACCAGGCGAG CCACAGGTATAATTTCAGATGCTCTTAGAAGTCACGCTAAAAGACTAAGTTCGCGGCTTT CGCTGGCCCTCTCCTCGAGGATCGAGGGAGCTCTGACCACAGCCTGTGGCTGGGAAGGGA GGCAGAGGGGCGGCTCAGGGGAAACGAGGCTGCAGTGGTGGTGGCAGGAAGATGTCAGGC AAAGACGAGCAGCAGGAGCAAACTATCGCCGAGGACCTGGTCGTGACCAACTATAAGATG GGGGGGTGACATTGCCAATGGGGTACTTCGGTCCTTGGTGGACGCATCTAGCTCAGGTGT GTCAGTACTGAGCCTGTGTGAGAAAGGTGATGCCGTGATTATGCAAGAAACAGGGAAAAT CTTCAAGAAAGAAAAAGAGATGAAGAAACGTATTGCTTTTCCCACCAGCATTTTGGTAAA TAACTGTGTATGTCACTTCTCCCCTTTGAAGAGAGACCAGGATTATATTCTCAAGGAAGG TGACTTGGTAAAAATTGACCTTGGGGTCCATGTGAATGGCTTCATCACTAATGTAGCTCG TACTTTTCTGACTGATGTAGCTCAGGGGACCCAAGTAACAGGGAGGAAAGCAGATGTTAT TAAGGCAGCTCACCGTTGTGCTGAAGCTGCCCCATGCCTGGTCACACCTGGAAATCAGAA CACACAAGTGACAGAAGCCTGGAACAAAGTTGCCCACTTATTTAACTGCATGCCAATAGA AGGTATGCTGTCACACCAGCTGAAGCAGCATGTCATCGATGGAGAAAAAACCATTACCCA GATTCCCACAGACAAGCAGAAGAAGGACCATGAAAAAGCTGAATTTGAGGTACATGAAGT ATATGCTGTGGATGTTCTCATCAGCTCAGGAAAGGGCAAGACCAAGGATGCAGGAGAGAG AACCACTATGTACAAATGAGACCCCTCCAAACAGTATGGACTGAAAATGAAAACTTGACA TGCCTTCTTCAGTGACATGAAAAGGCGTTTTGATGCCATGCCATTTACTTCAAGAGCATG TGAAGATGAGAAGAAGGCTTGGATGGGTGTGGTGGAGTGCGCCAAACATGAAATGCTGCA ACCATTTAATGTTCTCTATGAGAAGGAGGGTGAATTTGTTGCCCAGTTTAAATTTACAGT TCTGCTCCTGCCCAATGGCCCCATGCAGATAACCAGTGGTCCCTTCCAGCCTGACCTCTA TAAGTCTGAGATGAAGGTCCAGGATGCAGAGCTAAAGACCCTCCTCCAGAGTTCTGCAAG TCGAAAAACCCAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAGGCCTCCAAGACTGCAGAG AATGCCACCAGTGGGGAAACATTAGAAGAAAATGAAGCTGGGGACCAAGGTGGGTCCCAT CTCCCCAGCTTGCTGCTCCTGCCTCATCCCCTTCCCACCACACCCTAGACTCTGTGAAGT GCAGTTCTTCTCCACCTAGGACTGCCAGCAGAGTGGGGGTGTCCCTGCCGCCACCCCAGT TTTGCAACCCACTCCCTTCCAACAACAACCAGCTCCATCTGACTCTGGTCTTGGGAGGCG AGGCTTCCCAACCACAGAAGACTTTAATTGAACAAAAGAAATTAAATAATAAAATCAGGA GTCAAAATTCATTGTCTTCAAGCCCCTCTTCCTAGCCTTTTCTTCTACTCTCTGCTTGGT CAAGGTTTGTAACCCTACGATAGAACAGGGCTAAATTAGCCACCACCACTGAAAACTCAG CCGAATTTTTTTATACCATTCTGATGTTAGCATTTTTCCATCTATTTGGGGGCTTTTTCT TCTTTTTCCATTCTCCCCAAGTATTTTATCTGGCTTCAAAATTAGGAGGATTATTTTTCA GATAGTTTTTATTCGGTGTGGCCGACTCCTCATCTGATTCAGGCTGTCAGTCAGGCCCCT CCCATTTTAGGAGCTGGAGCCTTCACTTATGAAGCAATTCCCATCTATGAAATGGATCCT CATTTGTCAATCTTTTTTCTTCCATTTTCACAAAGCTATAAAGAAATAATCCATCTCAAC CTTACCCTTTTCTCTGGAGTCAATGGGGTCTTCCCTCACTCCATCTTACACAAACCTGAG CTGGAAGCTCAACTGGATTTGTTCCCTGTTTGAAATATTGTGATCTCCCTCCCTTGAAAG AAAAACGAAGAACCAGAGGAGTAGACTGACTGAAGATAAAACTCCTGGCTTTCTGAAGCT ATGGATTTGGATTGGATTGCTGGGACTTTGTAGAGAAAGGTGACAAATTTCAGTACCTCC GGCATGCTGTCCCAGGAAACTAGGGCTCCCACTAACTTATGAGGTTTTTAAACACATTGA AAATGAAATGACATTAAAATAAATTTGGATTTGCTCATTTAAAAAAAAAAGACTAAGTTT GCTTTAGTAATATATTTTATCTAACCCAATACACATCCAAAATACAATCCTTCTGCATGT CATGCACGCAGGTCATGAACAAGGTAGTGCATCTTGCCTTCTGTGGGCAAACTCTTTGTA ACTGCTCAAGGCATCTCGGCTCTGATCAGCACACTTCTGGTGCTCTGTATCAGGTGTGGT GTCCAGCTAGGATACTAAGCAGGGATCCTATGAGGCATAAGGAGGCAGTACCACCGACAC AGCCACTGATAGGAGGAGGTGCTATGGATCTGAGTGTGTTGAGGGTGTGGAAGCTTCTGG TTACTATAAATGAACCCTTGGCCACCGGCCCCTCCTGTGTGCCAGAGGCAGCTGGATGGT GCTAGTACCCTCTATGTCCTGTCTTGGTTTTTTTTGTTTTTTTTTTTTTTGAGATGGAGT CTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCTGC CTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGACTATAGGCGCC CACCACAATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGAGGTTTCACCGTGTTAG CCAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCAGCCCCGGCCTCCCAAAGTGCTG GGATTACAGGTGTGAGCCACCGCACCCAGCCTTTTCACTCTGTCGCCTAGGCTGGAGTGC AATGGTGCGATCTCAGCTCACTGCAACCTCCGCCTCCTGGCTTCAAGCGATTCTCCTATC TCAGCCTCCAGAGTGGCTGGGATTACAGGCATGAGCCACCACGCCCGGCTAATTTTTGTA TTTTGAGTAGAGATGGGGGTTTCACCAATTTGGCCACATTGGTCTTGAACTCCCCACCTC AGATGATCTACCCACCTCGGCCTCCCAAAGTGCTGGGATTATATGCGTGAGCCACCACGC CAGGTGTCCCGTCCTGTTAAAGCAGCTTTGGGATGCACGGCTTGACCATGCTTCCTCTGA AGTGACCTGCTGCACTGTCTCTAGACTGCATGGCTTATCTCCAAAGCCAGGCTTCAGAGA GGAAAGCTCACATTGTTCATCATTAGTCAGAGTAATGCACAGGACCCTGAGTGCCCATCA GGGATGGGATCTTGGGTGTTTTCCAGGTAACAGCCTCACAGGGCTGCAGCAGAGGACCTG GGACACCCTCCTGGGCCTCCTGAAACATGCAGAAGTAATTACCTCCCCTTTCAGTGTCAT TTAATTAAATCTACAGTCTTCCTGCTCTCAACTCTGTGAGACGTGGAACTGTATCTGCTA AAAATAAAGCCCAGCTCCTATGAACAGGGCTCCATCCCAGTGCAGGTGAAGCAGCCCTGC CTCCAAGCAGTGGGGCACACTCAGACCCTAGGGAGGCTGGGCAGCACCCACACAGTGCAC TTTATAAAGACTACAGGGTTGTTGTAAATTAAGAAGGAAGAGCTTAAATGCAGGCGGTAT CAAAACAACCACCAAACTCAAAGGAATTCACTTTCTGCACTCAACTCCCCATAAGCACAT GCAAGTGTAAGAGTTTGGGTCTAAGAAATCACACGCAAGACACAGCATTGTATCCTGTGG CTCTCTGGCTCCCCCAGACAGATGTCCAAGCCAACCTGTGCTCCTTTCTCTGAGGACGCA GAGCCCTTTGCTGCCTGTCTTATCCTATGCTTCTAGGGGAAGCTGCTGGAAGGCGATGGC CCCCAGGCCGTGTTTCCAGCCACGTCCAACAGGCCTGCAGTAGAGACCCCAGTACCCCAG ACCAATCTAAGCCAGGCCTCCCAGAACCATCTGGTCGCGGCCCTCGCTGGGTGGACACAC AGCCCTGACGGTCAGGTTCCTGTGGTGGCCGTGCTGTCTCCAGGACTCAGCATCACAGGG CCTGGCCCACAGTGGCACCGGGAACCACAATGCCTGCTTTGTCCCCACACAAAGGCTGGC AAAGCACCTTATATGGGCCACTTCACGCTGGGAAAAGTCCCTTAAAAGTTATTTTTGCTT CTACTTCAACCCAAGTTGTAGAATATATGTCTTTTTTTTTTTTTTTTTTGAGATGGAGTC TTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAAGCTCAGCC TCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCC GCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCACGTTAGC CAGGATGGTCTCGATAGAATATATGACTTAATCTTCAGTATGTCCTTTGCAAATGGTCTT GTGTATGCAGACTATCTATGATGTGAAAGCTGCATCCAGGAAGATCCCAGCCTGGGCAAG ACCAGGAGGGCCAAGGCACCCCTGAGGCAGTAGGAGTCACAACCCGGCTTTCTAAAGGGG ATGCAAGGACTTACATATCCTGCCTCTTACAGCTAAAGTCACATCTTGAAACGCCTTCTA ACACAGACACACCTGCATCAACCTTTAATCCATGTCTCCAGGAGTGGCCACAGAAGGTGG TGTGGACGTGGCTGAGGCTCCCCTAGCTTGGTGTGGCTGACATGGTCAGCCCCCCCCAGA TTTTCACTCCCTCCTCTATTTCCACACCAGATCTAGCAGGAGTGGACCTTGGGGGCCTTG GACAGGTGGGCCCTCCACCAAATCAAACAGAGCAGCTTCTTCTGATGACCTCTTCTCTTC TGGTTCCATCCAAGCACGTAAACAAGCCGGAAACGAGAGACCTGCATAGGTGGCTGCTGG CCGAAGACGGTCCCTCCTGGGGCTACCGAGGGCACTTCCCACACCCAGTGAGAGTGTCAA ACCGCAGTGGGTGTCCCACGGTGACGGCAGGGTGTGAGGGCAGCATTCTGCACAGGGTGA GTCCCCCAGAGCCTACAATCCTGCACAGCACAAGGACATGTCCCATGCCAGCCCAGGCCA CCCTCGGGGTGGCGAAGAGACACAGCCATGCCACAGCACTCCCAGCCCCCAGCTGACCCA GTGGGGCCCTGGCACAGGACTCTGCCCAGGCGTGTGCCTAGCACGGGTGAGGAAGCCCCG CCCCTCGAGGAAGCTGCCCCGGGTGGCTCTGCCTCTTCACATTTACAGAGAAGGAAACTG AACCCATGAAGTGACGGGCCAGCCCATGGCCCAGCAGCCCTGCAGGGCAGGCAGCCCGAT CCCAACAGTTGGGAGGGGGTGGGGACAGGGCCAGAGAAAACGGGTAGCCTGGGTCATAGC CTACAACAATATCACTTCATCACGCTGTGCCTCCATGGCCTCATCCATGACAGGGAGGGC CCAGTGCCCTTTGGGGCTGCCATGACATGCGGACTCGCACCCACATGCTGTCTGTGACAG GGCCCGTGTGGCCTGATGCTCTGAAATTTCAGACAACAAGCAGCCCCTTCGTCCACTCTG CACACTTGAAAGGCAGGGGTGGGAGCAAAGGTGTGGCAGCCCAGGGGGCTGTCCCCGGTC CACCTCACCCCAGCCCAAGCCACTGCCTTTGCCAGACCTCCCTGAACACGGGGCATGGGG GGTGTGAGTTAGTGGACAGAAGAGAAGCAACTGCCCACCAGATCCCGAAGACCCCTAGGG TCGGGTGAAAGACCACCTTCAACAACCCAATATGAACTCCTAGGCGCACCAGTCCTCAGG GGACAGTCCAGGCAGGGGCACCTCCTCAACTGGGGCCCTTCCCTTCCTGCCGGGGAAGCT GGTGCTGAGGCTGGGTACTGGGCTCACCACCAAACAAGCCACACTCAGCATTGCCTCGCT CATTGCCTCCCCTGCCCCACCCACTCTGACTTCCTCTATATCCACATCCCCTAAACCGAC CCTTACCACTCCAGGCAGAACCACCTGAGCTTTCAGAGACAGGCCTTCCTCCCTCACTTT CCAGACACCTGCCTGGCAGGTCACACAGTGAATGGGCATCGCTGCTGACTGAGGAATGGA ACACCGGGACAAGACCTTCTGAAAAGCCAGTTCCAAAAGGAACCATGGCTCTCAGGCAGA CGCCGAGACGCCGACACTTACCAAACCATCAGTGTCGTCAAACATTTCAGCACATGGTTT CTTTCCACTATCTGGTGTTAGCAGAGTCTGAAACAGAGTTAGAAAAGGGCACATTTTAGC AGGATAAACTACCAGATTCCCTTACAATATACATACACACAATTCCATACCCCAACCCTG TGCGAAAAATGTCCCCCAGGGACTGCAAGAGCATCGTCCTAGAGAACTGTCAGTTACAGG ATACAGCTTACCTGGCCACGTGAGACCAGAGGAGGCATCACAGCTAACAGACAAGGATTA TCAAGAACTGGGAGGGAGGCATCATCTGCACCTTCCTTCACCCTACCCATCTCTCTCCTC CCCTCTGCTCCTGGCCAGGCACCAACTTAGCAGAGAGCCTCTCCTTGGCTCAGCACACAA TCACTAGGCGTGAGCTCTAGTGCAGGAGGCAGCCAGGGTGGGCCAAGGCCTAACCCAGAA ACCCTGTGACCCACAATGAAGGTGTAGTCAAGAAGGACACTGTAGTACAAAGCTCCAAAA CAGTCCCTAATTTAAAATCACATATGAAGACAATGTCAGTGCTAGCATTCAATATTCCAA CACTTTTTAAGTTTTAAAATTAATTACATACTCAAAAACCAAAATCAGGAGAAGAAGGGG AGGAGAAGGAGGGCAAGGAAGAGAGAGAGAAGAAAAGAAGAATCCAAACAGGAACCAGAA TTTGGGAGAGTTTTTCTTTTTGAGACAGTCTGTCTCCAGGCTGGAGCGCAGCGGCACGAT CTCAGCTCACTGTAACCTCCACCTCCCAGGTTCAAGCAATTCTGCTGCCGCTGCCTCAGC CTCCTGAGTAGCTGAGCTTAAAGGCACATGCCACCACACCCGGCTGATTTTTGTATCTTT TTTAGTAGAGACGGGGTTTCACCATGTTAACCAGGCTGGTCTTGAACTCCTGACCTAAAG TGATCTGCCCGCCTTGGCCCTAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCAGCT GGGAGGGATTTTTTTAAATAATGTCAGAAGTAGCGGAAGGCTTACTAATGCCCCTGCATT AAGGAGAAACATGAATCAACACTCTGAGAAAATGCAAAGGGCTCCTTCCTTCCTCACTGG CCTCCTGGAGCAGGGAGTGAGCATCGCAAAGTCCCCTCCCACAAGGCACAGAGCCGCAAA TGGCAACTGAAGGGAAAAGCTGTTCGATGTCATTAACGATGAAAGAAACAAACTGAAGCA GGATGGTCGCTTTCATCTTTCTGATGAGCAGTAACCTACAAAGCTGAGCAACCAGAGCCT GTGATGGGGTGGAGCAACCAGAGCCTGTGATGGGGTGGGGAAACCAGCGCCTGACAGGTG GGGAGCAGACCCAGTGCACCTGACTGTGACGCTCGGGATGCTGCTGAATCACATTCCAAT TGGACACAAAGCTACACCATGAGGGTGCTTCCTGCATCGTAGCAAAGCCATGGAAACCTT CCAAGTCCATCAGTGGCTGACCAGAATCAAATAAATGGTCTATCCAAACACTGAAGTGTA TGCACCCATCACAAAGAACAAGGAGGTCAGCTGGGCACAGTGGTTCACGCCTGTAATCCC AGCACTTTGGGAGGCCGACATGGGAGGATCGCTTGGGCCCAGAAGTTCAAGACCAGCCTG GACAACACAGTGAGACCCCATCTCTACAAAACAAAGTTAGCCAGGCATGGTGACACATGC CTGTAGTCCCGGCTACTCGAGAAGCTGAGGTGGGAGGATTGCTTGAGCCCAGGTTGTCAA GCAGTGAGCTATGACTGTGCCACTGCACTCCAGCCTGTGCATCAGAGTGAGGCCCTGTCT CAAAAAAGCAAATAAACAAAAAACAGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGC CCTTTGGGAGGCCGAAGGTGGGTGGATCACTAGTTAGGAGATCGAGACCATCCTAGCTAA CACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGGCATGGTGGTACACG CCTGTAGTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCACTAGAACCCAGGAGCCGG AGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGTCGATAGAGCGAGACTG GGTCTCAAACAAACAAACAACAAACAACAAAAAACAAACCCTGAGGAGGTGACCTTGTGT GGAAAGGGAACTGCCCAAGACAGAATAAAAAGGCAGGCTGTGGAGGGGAGCCAGGGCAAG CCCACCACTCCACGGTGGCCTTACGTATGCATGTGAGTGGCTGCGCAGGAAACACAGGCT TTTGGGAGGACAGTCCAGAGAGTAGTAACAGGTTTTTCGTGCTGTGGAGTGGCCTGGGGA TCCGAAGGCAACTTGGTCCCTGCATTTCTGAGCTTCCGTATTAGGGCTGTTTTTACCCTG CACACTGCAACCGATACATACCACAGTTGCCCACATAGCACCGCCCCTTTTCTTTAGTGG AAACTACAAATTCCACATGGTGCATACATCCTACGGAAGGCCAACCCATGGCTGGTCACA CAGTTCCCTTCCTGGGCCCACCTAAAAGACTGCCTGCCACACACATGCCACACACATGCC ACAAACATGCATCACATGCATGCATACATGCACACACCCATCCAAGCAGACACACACCCA CCCACACTTACATGCACACACGTATACACCTATGCACACAGGTACACCACACCCACATAC CCATGTAAGCACACATGTATATTCACATACAAAATCACACACAAACCTACAGAGACACAC ATACATACACATGCACATATATACATCCAAACACGCACATCCATACACACTCATGCACAC ACACACATATACATATATGCACATACAAACATGCATGCCATATTCACATACACACTTATA CACCTAAACACACACTCATACACACACGGATACATATGCCCACATGGATACACATACACA CAAACACATGCACAAACATATGTACCTATACGCACACTCATATACAGATATACTGCACAC ACCCACATGTACTCATATACACATCTACCTACACACATGTGCCTACACACATATGCATAC TCATACACACACTGTGCATGGTCCTTATCCTCTCCCCAAGGGAGCTGCAGCCCAGCATTC CCACCCACTCACACGCTGGGGAAAGAATCACCTCCTTCCTCCTCAGCAGCTCAGAGGCAG GTTCTGAGCCATCGCAGCCTCCTAGAGACCCCATGTGCCTGTGGTCAGTGGTTCTCATAC TGCGGCCTGCAGCAGAACCCCTGGCAAGGATCTGAATGCCAGATCTCTGGGCCCCAGTTG GAGCCCCAGTCCGGTAGTGCTCTGGGGGGGTCCAAGAACATGCATTTCTAATGGGCCCTC AGGTGATGTTGCTGTAGTTCCAGTGAACAGCCTCTAGTCCCTGGGGCAGCTTAAGGGAGT CAGGGTTTGGATGTGGCTCATTCATTCCGTCAGTGAATGCTTTTTGCTTCTTTTGTGTGC CAAGCTGCATCAAAAGTCCCTGGCTCTCCTGAGGACGCAAAGAAACAACTGGAGAAAGTC ATTTCAGGGAGTGAGATACTGATAAGGCAAGAGCATGTCAATGTGAGAAACAGCCTACAA GGGTGTTGGGGGGGAGTCTTATTAACATTCCTGAGGGTCTTATCCTCCTGGAGAGATGAG AATCCCCCTGCAGACCCAGAGCCTCTTCCCTGCAGCTGTCCCTGCTCAGCCCTGGGTCCC AAAGGGGGCTGACCCTCATCCTCCCTGCAAGCCTTGGGGGCTGCCCCTGTGTGTGGCAGG CACCTTCCTTCCTGTCTCCACCTGGCTCAAATGCCACCTACCTAGAAGCAGGGACCAAGG TCCTCAGCTGGTCAGAAAGGCCCACACGCCACAAGACCCAGGCTAAGATTTGAGGGCCCA TGTGGCTAACACGAGGGAGCCCAGGCCAGCATTCAGTTACTAAATAACACACCCTATTCT GTGTAAAACTCTGGGTGACAACTGCAACAATGTCAAGTGCTCCTAGAAAACAGCAGGAGG TAAGAAATCCCCTGCCCTCTGCGTTCCAGAAACAACTGCTACAAAAAAAGCCCCTTCCCC ACAGGACTGAGCTAAGGCTCACGATGCCCCCACCCACCCAGGATAAGGCCAGACACAGAA ACCCACCAACGCCTGCTCTGTGCCTCTTGATGGCCAGTGGCACGATGCATCCCCCGCCTG CTCCCGATCACTCACAACAAAATGCTCATAACCAAACCTTGCTTCGCTTCTGTCCTTCTC CAGGCCCCTTGGGTCCCACAGAGCCAGTGCAGCCCCTCCTGAGAAACAGCTGGCCTTGGG TAAGGCATCCTTTGACCCTGCCACCTTCATCCCATATCCCACCTCTGGTTCTTCGAAGCC TCATCTACACCACCCTACAAAGAAAAGCCCTTTGGCCTAACCTTTCAGACACATGTGATC TCATGGTCAGCATGTGGCCAGGCCCTGGCCCCTACTGTGACAGTCCATTCCTTCCTTTGC ATACTCCTAAGAAAGCCTCTTCTTACTAAGTCTGGATTTGTTTTATATTTGACAACTGCT TACTGATTACAAACAACTTGAAACTCCAAAATGTGTCACACACTCATGCAATGGATGCAC AGGTGAGAGCTTTGATTTCTGCCTCCTGGAAGACCGGTACTCACATGTTTAACCGAGGTT CCACCGGTTCAGACCCACTGCTCATGAGACGGCTCAAGAATATGTCAGAGATACCCCAGC CTCACATGCACAGCTGGTCCTGGAGGCCGCAGAGCAAGGAAAAAGGGGAGAAGCAACACT GAAGGTGAACCACACCCCTCACAGACACGGGCATCCTACAGGCCCAGGAGAACCCATGCC CTCCAGCGTGGAACTCAGCACACTGGGCATTTTGTGTAAGCTGCCCTCCTCCTGCAGACA GGCAGGGCTTAGCAGGGCCAGCTGAAAATGACACCTAGCCTCATATGTGGCCACCACATA TGCCGAAGGGGAGGACGGAGAAGGCGACCTGCTGTTCCCCACACCCCGCAGCAGAGAGAA AGGGCTCCCAGGGCAGACAACCCTATCACCTAATCCTACAGTCATGCTCGGGGGCTCTGC TGGGCCCCTCAGCACACTCATGAAGCCCCAAGGTCTCTTTTCTAAGATCACTGCAAACTG CAACTGAACACACGAAAGAAAATGTGCATCTCACTGGAGGTCAGAAAAATGCAGATTAAA GCAAGATGCCACTCTCCCCCTACAAAATGACCAGAAAAAATAATTACAAGGCTTAAGGTG GTGTGGAAGTGTGAGCCCCTCCCTGCTGTCAATGACTTTTCTAGCAAGCAGCATGCCAGG GATATCAGGAACCTTACAAGGGTACCTCTTAGCTATCAGCAACGAGCAGAAATTGGGACC GGTAATCCCAACAAAACGTTTCACCCCATATACTCTTGACTGTGAAACTGAAAAGCGCCC CCACAGAGAGAAGCACGTCAATAGATAAAGCAGCACTCGGGCTCCAAATTGTATGTTTGC GTCTTTCACATGGATGGCTATGAGCAAATGGCTGCAGTTCTGAGTCCTGACAACTGAGGA GGCAACGGTGACTCACTGCCCTCCCAGGACAAGTGTGGGCACCACAGGAAGGCTGCCAGA ATAAACCTCCAAACATTTTTCTCCTATACTAGGAGAGTAGCATATGAACAGAAATCATGG TGTCCTGGACATCATAAACCCCCAGAGTCCTGGGAAGCCTGAATCCTAGGGCCAATGTGT ATTTCTTTTTTCTCTTTTTTTTTTTTTTTTTTTGGAGACAGAGTCTCGCTCTCCCTCCCA GGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGGAACCTCCACCTCCCGGGTTCAAGTG ATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGTGCGCCACTACGCCCGGC TAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAAC TCCTGACCTCATGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGA CACTGTGCCTGGCCTGATGTATATTTCTTGAACAACAAATGGGTAATTTTAAGGCTAGGA TGAGTTTTACCAACCTGCTTTTCCTAGTGATGCATTAAACGTGGTTTGGGTTAAGAAGGG AAATTCTCAGGCTTTGCTGAATCCCTAACTGAAGCACGTGAAGCTAAAATCACTCCCTCT CTGCCCAGGGTGGTCTGCACACCCAGAAAGAAATGCCAGAAATCGCTTGGTGTGAGTGCA CTGCAAATTCTTGAAACTTGATTTCTCACAGGTATAGATCATCTGGCTAACTCAGTCCAG AATTTAAATACGGTGCTATTATAATTCACAGTAACTAAGATTATTATCTGTACATTAACG TATGGCACAAAAGCCCATAAGGCTAGCTTCTACAGAGAAGCAGGCTCCAAGGGAAGTGGC CACCAATGCTCTTCCTTTATAACAACATTGATGTGAGCAACGGCAGGCAACCGGCTGATA AAATGTGGAAATGTTTTTCCCTGTGGCATACCCACTTAAGGAGAGCTGTGTTTTCTGTAC AAAATAGGTGGGGTTGTTTTTGGCAAAATGATGGAATGTTTTCAATTTGAAGGAGTAAAA ATTCCCCAATACCAGTCTACGGCAAACAACTCAAAACAACAACAAGCCAACAACACCTCC TATTTAAAGCTGTCCCAGCCAGATGCAGGGGCTCGTGCCTGTAATCCCAGTACTTTAGGA GGCCAAGGCGGAAGGATCACTTGAAGCCAGGAGTTCAAGACCAGCCAAGGCAACAAAGTG AGAGCCTGTCTCTACAAATAAAAAACAATTAGCTGGGTGTGGTGACATGCACCTGTAGTC CCAGCTACTTGGGAGGGTGAGGCAGGAGGATCACATGAGCCTGGGAGTTTGAGGCTGCAG AGAGCTGTGATCATGTCACTGCACTCCAGCTGGGAAAAAGAGCAAGACTGTGCTGGAAAG AAAGGAGGGGGGAGCGAGCGAGGGGAGGGGAGCGAGGGAGAAAGAGAGGCATGTAAGAGA ACACAGAAAAGGGAAACAGAACAAAAGGGTCTGTACTCTGAACACTAGAATGTTCCTTTC TACTCCTTAAGCCAAACCTAGAAGGCTTCTGGCACTCTCTTCTCTGCATCCCAGTACCCA CTTCCAGGTTTCCAATGTGTTGAGTTCAGACTGGGGAATACCAGATGGGGAAAAATGGTA GACTCATGCCCAGTTGAGGAATACTTGCAATTCTAATCTTCCTCTCCAAACCACCTGCTA CTATATTCTTTTCAGAATCTTTGAATAGCTGCTCCCTGCATTTGCAGTGGGAAAGCCACA GTGGAACATGGTTAACCCAGCTTATTAACCAAGCCCATTCATTTCTGAGCTAAAAATCTA CCTGAGGCTCACACCAGCCATCTTTTGCATGATCCATCTGGTCCTCTTCGTAGACAGGGG TCCATTCCCAGGTGCTAAATCTGTTCAGCAGGGCTACTTGGGGGCTTTTCATGATCAAGT CCCAGACTTGCTCTTTCTCATCCAGGTCATGACCAGCCCTTTTTCGCTGCTGCTTTTTCA TTTTCGCAGCAGAGGTGGGGAGGTACAAAACTAATTAGCGTCAACCAGTCTCCAAAGTGT ATTCACAACACAAGGTCTCTATGTTGTGTTTAAAGAACCAAATGGTGGGCCGGGCATGGT GGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCATATCACGAGGTCAGG AGTTCAAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATATAAAAATT AGCAGGGTGTGGCGGCGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGGC TTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCCGAGATTGCACCACTGCACTCCAGC CTGGGTGACAGAGCAAGACTCCGTCTCAGACAAAAAAAAAAAAAGAACCAAATCGTGCCA ACTAGAGCCAAAGGCTTAACTTCAACCCTTGCAGTCATGGGGGCACTTTCTCCACTTTCC ACCTTAGACACGTGCTTTTGGGGTTCTATGTGCTTTTCTTAAATTTCAGAATCAGAACAC CAGTCAAAAATGGAGAGTGTGACTCACCTTCCCCCACCCCCAAGAAAACTGCCACAAAAC CGCACTGTGAGCCTGTTTCTTCCTCTCTTCTCTCAGATGCACTACGCTCTCAGGGACCAA GGACACTTTGTTCTAATCATGTTGAAGATGTAAAACAAAAATACTTAATTGTAAATTGAA TTATTTCACCAAGATGCTACCTGTGAGAAAAAAGGAATGGCTGGAAATCCTGCCTTCCGA CCTGGGTTTCGGATGATTATAAACAGCTGGGGTGGGGCTGAGGACCTCAGGGGCAAGGCA GCCACAGTTGGGGGTGGGGGGCAACACATTACAAGTCCAGCAGCAGGGCGCAGCCAGGCT GCCTCTGGCCACCTCCCCAATGCCCAGGATCTGGACAGGAAAAGACAGGAGTTCATCAAT AAGGAGAGACCCCTCAGATGTGGGGTGCAACACCCCAGCTAGGAAGGGCAGCAACAGGTC CTCTCCCTGCAAGATCATGGGAACAAAGAAGAGGACAGGGACACTGAGGACAGGGTTCAA AACCCACTGGTCTCCCCAGAGTGAAGCACCCCCAGGGGAAACTGACAGCAACTCAGGCAG TCACAGAGGTCAACCATCAGAGAGGTGAGTGCTAGACAAAAACCACATCCTCATTCTTTG GGTCCATTAGGAAATGGGCAGGGTTGCAGGGGTCCCCCGCCTCCTGGAGAGGGCTGGATA AGCCTGAGTTACCACGGGGTGTGGGGGGAGGGTGCGGAGAGCACCCCCAGGGCGAGGGTC CTGCTCTCTGCTCAGCCCACAGTGACATCTCTAATGCAAGCATATGCTGGCTCTAAATTA TATTAGCTTGCTTGCTTTATTTGGATGCATCTCTGTTTTTGACACCATGTCCTCTCTATA GCTATAAACATCTCGCATGCTTTACAAAGCACTGAGCACACAATAATTAACCAATACTCA CTGACCAACCTGTCAGGGGCAAAGAGGACCAGCCCAGGAAGGGGGCACATTTCCACATAT CACCCAAGAGCCTCTCACGCTGGCTCAGACCCACAGACAAGACTGGGAAGATCCGCCCAC AGAATGTTCCTCCTTGCCCTCCATGACCAGATTCTCACTTTAAAAAGAGCCCTTAGTCCG GTGCATCCCGCGGAGAACAGACAAGAGGGGCCTAAGTCCCCAGGAAACCAGCACCATCCA TCCGGTGAGATTGCTGGCCACTCAGCCCAGGGGTGATGGCTGCTAACGGGTCACTTAAAA AAAATGACCATGCATTAAAAACATTATTAAATCATCACTCACAAGAGAACCAAGGAGGTG TCACAATCCCTTCAGAGGGGAAGTCAAAGAATCACAAAAAGACATGGAGTTGGCTGGGGG AATGGGGATGGATTGGGCCATGATGGATTGATAATTAGGGGGCTTCCTTTTGGGGTGCTG GAAATGTCTTGGAGCTAGAGGTTGCACAACATTGCAAATGTACTAACTGCCATGGAACTA TTCACTTTAATATGATTAACTTTATGTTATGTGAATTTCACCTCAAGAAAAAAATAATAC AGAGTAAAAGAATATTGACATGAATTTCCAACGGACACAATACCAGCCTTTTCCATGGGG AGTCAATTGTCTCTCCAGGAGGCTGAACCCATTTGCACGTCTAGGGACAAGGATTATTTG CATTGCCTTCGGATATCTATGACTTACAGAGCTGTACAAAGACAGGTGAGCCCTGGGTGG CCCCAGTGCTCCATTCAAAGGCTGCCTATGCCCAAGTCCAAGGTGGAATGAGGAGAAGAT GGAGTCCACAGGTTTAGGAGGAAACCAGCTTTAGCCGATGGGAAGGTGATGCTGCAGAAT AAGGTGTGTCTAGAGATGGTGTCAGGAGTGACTCCTGCATTTCTTGGAGGCAGGGGGGAA GGTGGGCTCACTGGAGCACTGGGGCTTGAGGAGATGGTCCACCATGTGACACAGTGAGAA GCCGAGGTGTCCAAGGCACCATGAAGGGGCAGGACCACACAGGGTGCACGCCAGGCAGTT TGCAGCCCTGGCCTGGCTAGGGGCTTCCGTAGCACAGTGCCGCAGCTCCTGGGGCACACA CCAAGGGATCAGGCACACGAAATGCTCAATGACACACACAAACATAATTTCCCCTGACTT GTACAAAAAATAGGGTGATCACTCCGCTCTGAGTTCCCACGTAGTGATGCAGACTCATTT TCAGAAACGCCTTTTCTTTCTGCCAATCTGGAATTCTTTCTGGGCTCCTCGAACACCTCT AAGAATCCACAACCTTAGACAGAGGGCTGCCTGGGGCCTTTCCCTTCCGGCTTTCCCCAG GCATCCACACCTACAACACCTGGGACACGCTAACACTCACAGGCCAGGTGAACACATGCT TGACTGCTCTCCATATGTACCGAGGGCTGCCCATGACCTCTGTGAGTGACCTTTCTGTCT AGACCATACGCAGTGCATCATCGAGGGAGCACACAGCCCCCGTGTGCACAAGGTCATGCT CCAGAAGCATCACTCACCTGCATGTGCACACTCTCAAGGCACAGCCAACTCCACTTTTCC ACTGCAATTAGTACACAGTAATTATTACCCAAACCCAGCACATGGAAACATGGTCTGCAG CCTACATGGACTGTGTTTCCAGTGAGTTGTCCTTGTGTGCAGCAGGGAGGCGGCTACCAG GTCACAAGCATTCACCTCGGAGTGCACATGACGATGACCAATACGAGCCTGATGTCATTA TCGGAGCCTCCTTCAAGGATGCTGCTCCCTCCCCACAGTGGTCTTGTTACTCTATAACTA GAAGTTTCTGAGCCACCAGCTCCAGAATGCAAGGCCCAAAAAGGGCCCTGTTACTCTTTT ACAAGCAACCAGAGCAGAAACGAAAATGTCACCAACCTCCCAGAAAGAAACTGAATTATT CATCTGCAGCATTCACAGCCCCATGTGTGAAGTTAACGGGGGTTGTCCCCCTTGTTGTTC AGGCTGAAAAGTTTCCATGACTAGATGTGGGCACTCCTGTCCCAGCTCGTGTATCATGCC TGCCTCCTTCCTGGTGGCCACACAAGGACATGGGTACACGGCCCTTGCACTTGTATGAGC ACGTGCCCACCCTTTCTCCTCACGTCCTCACATCCCCAGCTTCCCGGCTCCTTACACCGT AGAACCTGGATGACCTTGTGAAAACACACACATCTGATGCTCCCTCCGAGGTCCCTATAC CACAGCATCCTTTGAGTTCACAGCCATCCGGTTCCTACAATTCAGCCCCAAAGGAGACTA GGGCCATCAGTTACATAAGGACATACATGGTGGAGGAGTTGATTTCATTCTCCTCCTTTG AGTTACCTGAACTTCTTACAGGAAATGTGTTATTTGTTTAATCCGGGGGAGTGGGGGAGG GGGAACCACACCTGGGAGCGCATGATTTTTTTTTTTTTTTTTTGAGACAGAATCTCACTC TGTTGCCCAGGCTGGAGTGCAGTGGTACAATCTCAGCTTACTGCAACCTCTGCCTCTCAG GTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAGGTGCGCACCATC ACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGATTTCACCACGTTGGTCAGGCTG GTCTTGAACTTCTGACCTTGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACA GACGTGAGCCACTGCACCCAGCCTCATGATTCTTATAAATTGCTGCAAGGATATGCCCAC AGCAGAAGCAGGGAGAGCTGGCAGTGGCATGTCCCACAGCCTCAGGCTTGGAGAGCAGCC CTCCCAGCCCCAAGGGCTCTCCCAGGGCTGGAGGTGCTTAGCCAGCTGTTTATGCATACG TTACACAACCCTGCAGCAGAAAGAGAGTCAGCCTGTCCAAAGAGAATCATTTGCGAGAAG ACACCGAAAGACTAGGGTAGTCGTGGTGTTAGGCCTGCTCATCCAAACGACTTTGATCAC TGAGAAAACTCAGCGCCATAGGATGGCTCCAGGGATTGCACAGAACCCCACTCCACTCCA CCTGCAACAGGTATTTCCAAACCCTCCACATTTGCAGAAATCTATTTTCTTTTTATTGCT CATAAATCACTCTATTTTAAACCCCAGCATGACACAGATTTTTTAATTAAGTGAAGCAAA ACTAATCTCACTTGAAGAATCACTACAAAACTGTGACCTTTTCCCTCACATAGGAAGATG CTACAATATCAGGGTCAGGAACCAAATTCCCCAAAGTCCATCAATGAAAAAATGTCTACT TTATGACCTAAGATGAAAGCTGACAACAGAGCGTTCAGAAGGACACACCGTCAACTGTCT TCAGTCCCTGACTCACCAAATAAAAAGTGACGGCAAAGCAATCTCTGCTTAAACATCACT CTAAAAACATACCACTCCTTTTGGCCTTATTTTTCTTGGGTTTTTCAAACAGGCTAATTT GTGGCCTTTATTGGAAATAAACAAAACATAAATAAATCAGTACCTATCAACACGCCACTC AGAATAATCACCTCAAACACCCTGGAAAAGTGGTGAAAATCTCATCCCCCCTCTAAGTGG TGGCTGCGGGTTTCTTCTCACTCTGGTATAAGGCTGCCCAGATTCTCCCGGTGTGTAATG CTTGTGTAATGCTCGGGGGCAGCAATCTGAAACTTCTAGAGACACTGAAGTCCTGCAGGT CACTGGGGTAGCTCCTATTAACTTACCACTCAGGCACCAAAGGCTACCCCAGGGCTTAAA AGCCTTAATGTCCCTCCTAAGGCACCTCATTTGCTGCTCCCCAAGGGGTACCATGTAATC CAAGGGAATCCAGCCCCATAAGAATCTGGTAATACCTAGGACTACAGACTACAGTCCTGA TTAGACTGGTTCCACACAGAGGCTGCATTTAAAACACTAGCCCTGAGGTCCTCATATGTT AATACATTCCCAATTCCCAATATCAGGAAAGAAGGAAATGTTATCACTACAGACCCCATA GACATTAAAAAGGAACATGGCAAACAACTCCGTGCACAAAGAGTCAACAACTTAGAGGAA ATGATCAAATTTCTCAATAACAACCAACCACCAAAATTCACACAAGATGAAATAGATACC TGAGCAATACTATAAACAGGAAAGAAATAGAATATGTAGTTAAATACCTTCTGAAAAAGA CATCTGAAAAGGCTCAGAGATAGGTTCCTTACATGTTTGGTAGAATTTTCCAGTAAAACT AACAATTACATACACTCTCTTCCAGAAAATAGAGGAGGAAAAAACATTTCCCAACTTAAA TGAGGCTAGCACTACCCTGATAGCAAATCCAGAAAAAGACATTACAAGAAGACTATAGGA CAATACCCCTCATGAACACAGATGCAAAAATCCTCAACCAAATATTAGCAAACTGAATCC AGTAATATGTAAAAATAATGCACCACAGCCCAAGGGAGTTGATTCCAAAACACAAGATTG ACTCAGTGTTCAAAAATCAATAAATGCAAGCCACCTACTCACAGAAGAAAAAGCACACAG GCATATCAATTTATACAGAAAATGCATTTAAAAAATTCAACATCCATTCATGATAAAAGC TTTCAGCAAACTAAACCTAGAAGGGAACTCTCTCAGCCTGACAAAGGGCATCTATGGAAA ACTCACAGCTAACATCATATTTCATGGTGGCAGACAGATGCTTTCACCGAAAGTCGGAAG CAAGGCAAGGATGTGCTCTCACTACTTCTCAACATTGCACCAGAAGTCTTGGCTAAAGAA ACAGGGCAAGAAAAAGAAAGGAAAGGCACACAAACTGAAAAGAATGAAATAAAATGGACT ATTCACAGACAGCATGACTGCCTATGTAGAAAATTCCAAGGATTTCTTTTTGTACAAAAA AGCTCTTAGAATAAGTGAGGTTAAGCAAAGTCAAGAGGGTCCAAGATCAACAACATAAAA GTGGTCATATTTCTATGGATTCTATCAACATTTGGGAAATTGATAAAGTGAACTGCATCA AAATTAAAATGTTTGGCTCTGTGAAAGATGCTGTTAAAAGAATTAAAAGGCAAGCTAAAG ATTGAGAGAAAATATTTGCAAATCACATATCTGACAAAGAACTTGTATTTAGAATATATA AAGAAGTCTCAAAACTCAATATCAAGAAAATAAACAACTCAATTAAAATATGAGCAAGAC TTCAACAGATACTTCACCAAAGAGGATACACAGATGGCAAATTAGCACATGAAAAGATGT TTTACATCATTAGCCACTAGGAAATGCAATTAAAACCACAATGAGCACATTATATATACA TTAGAATGGCTTAAGAAAAAACTTAACAATACCAGGTGCTGGTAAGGGTACACAGTGATG TGGCTGGTGAGACTGTAATATGGTACCGCCACACTAGAAAAGACTTGGGCAGTTTCTTAT AAGAATAAACACACACGGACCATATGACCCAGCAATCCCACTTCTGGACATTTATCAAAA GGAAATGAAACCGCATGTTCATAGAAAAGCTCATACACAAATGTTTACAGCAGTTCTGTT CAAACACACAATGGACTTACCGAGGGACAAAAAAAAAACCAAACTATTGATACCTGCAAC AGCTGGAATGAGCCTCAACGGCACAGTGGTGAGTGAAAGAAGTCAATCTCAAAAGGCTAT GTACTGCGTGGTTCCATTATATGACATTCTTGAAAAGGTAAACTATAGGAACAAAGAGTA GCTCAGCAGTTATAAGTGATTGGGAGGGAGCTGAATATAAAGGGATGGTATGGGAAGTTT TCTTGGAGGATAGAATTTCTCTGTATTCTAACTGTGGTCGTGGTTACACCATCTGCACAT GTCTTAAAACTCACAGAAATGCACACTGAGATAATCATTCTTACTGTGTATTAATTTTAA AAGTAAAGGAAAAGGAAAAACAAAATAAAATGACTGCACCAATTTGATTGAAATGTCTTT TAAAATACCTTTATTTTTAGCCAGACACAAAAGGAGAAACACTGCGTGATTCCACTTATA GGAGGTCCCTAGAGTAGTCAGTCACAGCGACAGAAAGGGGAATCAGGGCTGGGGAGTTAT TTAATGGGTACAGAGTTTCCATTTGGGATGATGAAAAACCTCAGGAGATGGAGGGTGGTG ATGGCTGCCCAACAATATGGATGTACTTAATGCCACTAAACTATACCCTTAAACATGGTT AAAATGATCAATTTTATGTTTATTTTACCACAATTGTAAAAACTCATGTTCTTCCACAAG AATAGATTTAGAAAATTGTATTTGTATAAAAATAAAACAATAAAAGAAGTTCAAAAAGCA AAAAGCTAAAGTCTCTCCCCACCACACTCTCCAGATAACATCACTGTCAACAGCTTGCTG TGCTTCATGTCAGATGTTCACAATCTTTATCATACACACTGGCTCAGGTGCATGCCGGCT CAGATGCATGCCAGCTCAGGTGCACGCCAGCTCAGGTGCATACAGGCTGAGGTGCATGCC AGCTCAGGTGCACACCAACTCAGATGCATATAGGCTGAGGTGCATGCCAGATAGGGTGCA CGCTGGCTCAGGTGCATACAGGCTGAGGTGCATGCCAGCTCAGGTGCATGCCAACTCAGG TGCATATAGGTTGAGGTGCAAGCCAGACAGGGTGCACACTGGCTCAGGTGCATACAGGCT GAGGTGCATGCCAGCTCAGGTGCATGCCAACTCAGGTGCATATAGGTTGAGGTGCAAGCC AGACAGGGTGCACACTGGCTCAGGTGCATACAGGCTGAGGTGCATGCCAGCTCAGGTGCA CACCAACTCAGGTGCATATAGGCTGAGGTGCACGCCAGCTAGGGTGCATGCTGACTCAGA TGCATACAGGCTGAGGTGCATGCCAGCTCGGGTGCATGCCCGCTTAGGTGCACACAGGAA TAGGGGCTTCTAATTCTGTGATTAAATGTGAAACAGAGGTCCTGGGTCAATTTGCACAAT CCTTCTGACTTTAAAAGAGTCATGCTCTTTGCTTCCCACAAGAGGCAACTGAAAAGTAAG TAAAACACATCCCAAGGGTGAAGTCACTGGTGGAGGGTAAAGAACACAAGATGGCAGCCA CCAAGGGCTGGGGAGTAAAAGTCCTTCGCAATTTCTGACTGTCGTAAGAACTCGATGAAG GCCAGAAAGGAGGAGGAGATGGCAAAGTTAGCTGGGATTGAGAAGATGATGGAGACAAGA CACTTACAAGATGGACAGGAATGATCACTGGGCATCCAAGAACAATTTATGAAAGCCAAA TATACAGCCTTAAAATAGAATGTGGACCTAAACACTGAGAAGCACCCCCCTTTTGTAAGA TTTGTGACAAAAATTAATTTGAGTGGAGTTAACAGTCCTAACGACATGGTGGACCCAAGA GCCAAATCACCGCTAGCAAAACGGCAGAATTCATATAGCATTCAAAGATGTCCTGCAAGA GCTTTGGGCCTAATGATGTCGGTGCTTAATGATGTCTATGGAATATATGAAACTTCCTCA GCTGCGCGAAGGCCAATGTTACAAGTTAATCAAAAGGAAAAACCCCAGGCCCTTCCCCTT TTCCCCCATTCAACTTAAGTAGTCTTCATTTCCCACAGTAGTAAATTTTCTAGATACATC TTGTAGACCTCAAAGTACTGGAGAGGGCCAGGCATGGTGGCTCACATCTGTAATCCCAGC ATTTTGGGAGGCTGAGGTGAGAGGAGTGCTTGAGCCCAGGGGTTTGAGACCAGCCTGGGC AACATAGTGAGACCCCATCTCTATAAAAAATGTAAAAAAATTAGCCAGGCATGGTGGCAC ACGCCTGTGGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGGAGG TTGAAGTTGCAGTAAGCCAACACTGCACTCCCGCCTAGGCAACAGAGCAAGACCCTGTCT CAACAAATAAAGTATTGGAAAGGAAGCGCTCATTCAACTTATCTTAAGATACTGTAAGAT ATCTGCCACTTTTCCTAAGATATTGTAAATGATACTACATTTTGAAATATGTAAGTTGTG CTATAACAACAACAACAACAAAACATCCTAGGCCTGAGCAAGCAGTGCTCCATTCGGAGC TGACCCAAACCTTAAAAAGGAGCAAAGGCTGGGCACAGGGTCTGACGCCTGTAATCCCAG CACTTTAGGAGGCCGAGGCAGGACGACTCCTTGAGTCTCAGAGTTTGAGACCATCCTAGG CAACACAGCAAGACCTCATCTAGAGGTCTAGATGAGGTTTTAGTAGACTAAAAATTTAAA AACTAGCCAGGCATGGTGGTGCACACCTGTGGTCCCAGCTACTCAGGAGGCTGACATGGG AGGACTGAAGTTCAAGGTTGCAGGGAATCAGCCTGGGTGACAGAATGAGACCCTGTCTCA AAAACAACGGCCGGGCATGGTGCCTCATGCCTGTAATCCCAGTACTTTGGGAGGCCGAGG CAGGTGGATCACCTGAGGTCAGGAGTTCGAAACCAGCCTGCCCAACATGGTGAAACCGTC TCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCACATGACTGTAATCCCAGCTACT TGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTTGGAAGCAGAGGTTGCAGTGAGCTGAG ACTGCACCACTGCACTCCAGCCTGGGCAATGCACTCCATCTCAAAAAACAAAACAAAACA AAACAAACAAAAAAACAAAAAGAAGAAAGAAGTGAAGGCAGACAGTCAGAGGGCTACAGA GACTCCAGGCTGGTCAATCAGTGACAGAAATTTGAGTTCCCTTTCTCAGGTCCTCCCCAG GCATCCCCCAGAGAAGTAGGACAGAGAGAAGACGGGTACCATGCCCACAGCAGCACTCTG GGTCCCCCAAGGGCTGCCTTCACGGTCCCCATCCCAGCCCAAAGGAGTTCCAGCCACTCT GCTGATGCATGGCACCAAGTTCTGGGCTCAAGTCCTCCCACCTCCCCCTTTGGTTGCCAA GAAACCTCCCTCCAAAGATGTCCAAATTCAAACTGCTGCTTCTAGACACCTGGCACCAAT AAACCCCGAAGATAAACACAGCCTGACTCATTTACCCAGCCCTGTGCATCGCAAGCATTT TAGCCATAATTAACCTTCGCTTAAACCCTGTGTTTGTGCTTGAGTTTAGCAATCACCAGC ATTCGAATCCAAATAAGAACATCACAAAGATTACAGTGGACAAATAAAATATAAACAGAT CCAAATGCCTCCATGTTCTTAATTACTAGCTATGTTCCTTTGTATACACAGATGAAAGCA GCAACTAAATAGCCTGCGTAAACTGCGTTTACATGAGTTTTTCTCTGTATGACCAGAAGC ACTAAAACTCACCTGCAGAACTCCACTGAGCTTCAGAACCCGTGGGTGATTTTTGTTTTT TCAGTGTGTACACTTCATTATCGTTTTCAAGCCCACCCTGGAAGAGGACAAGGGCTAAAA CATGAAATATTAAGCCACTCTCCCCCAAGCTACAGACACATGTAGCTTGACAGACACATG TCAGCTTCTGCCTGACAGACATATGTCCCTCAAAGAAGAGAAAAAAGCCAGACGGATTCT TCCCACACCACCACGTTCCTCCTGGCCAAGCCTTTCCGTAGAGAAAGGCCAAGCTGGGTT CAAGACCGGAGACTCTGCTCTCAGGTCTGTGACTGTCAGCCCCTGCAATAGGGGTCCCTG CTGCAGAGGCCCCTGGTGTCCCACCCTGAAAAGTCCCAGAAAGCACTTCTGAGAGCAGCA GCTCTGGCTTTAGAACCTGAGGAGGGTGCCTGGGGCTACAGGGAGGGTTTCACAGCTGCC CTGCTGGCACCATGTGGTCACCAGACCCCTCTTTCTCCCCAGCTCCGGGCCCACCCCGGA GGAGGCTCTCCTGGGGAAAAGGGTCGAGGTGCAGGATGAGAAAGAACCTGCAGAACCTGC AGCTGGAGGACAGACCAGCCACAACCTGGAGGCCATCCTGGGCTGCCAGGAATGACCAGG CTTTGTGAGAACCAGTGTCACAGAGGCTGGGCAGGAAGCCCCAAGGGCCTGAAAGCAGGT GGGACTGAGACCCATGTCCCCACCCACCTGGGAGCCAGAAGGGGCCTGCTGGGCCCCCAG ATCCTGAGCCTCAGCCAGTGAGAAGCAGGGAAGGGGACACATGCTGACCACCAGTCCCAG GAACAAACACCCACTCCTGCCAGCCCAACCACACCAGGACTGGTCCATGGGTCACAGCCT TGGCATGGGCTCAGCTCCCCACTCCCACCACACGGCCAGTGACCTGAGTCCCTCCTACCT CTGTGACCAGCTCCACTCTCTCACTTGTTCACCCATCAATCATTCATTCACTCCAACACT GCACCTGATGGAAAAGAAAGAGAAGAGCCACCTTTACCAGTCCTGGAGCTGGCACCCCTC TGCATTCCCCTACTGATCCATCAGGCAGCTCCCATCCAGTCCAGACCAAGCCTGCCGTGG ACCACCAGGCTGTGTTTCTCCCGCCTCGCTGTGACTGTTTACGGTAGAATTCACAGGATG GCACACAGGTCTGATAAGAGCACGCCAGGCACACGGGAGGCCAATGTCAGCAGGCTCACA GAGAGCGGGAAACAATGATATGACCATGGCTTGCACAAATATTTTTTTTCCCAGAAAAAG AAAATATCATGGAGGCAGAGCTCCCAGGCTTTCTGCTAATAAATGCCTCTAGCATGTCCA AGCCATGTCACATTTTGAAGGAAAATGAAGCAGTTTTTGGAAGGAGGACAACAGGAATGG TCCCCAGAGGCACCTAAGGTATTACTGATGCTTAAATATGGGGCCAGTGGTGACCGGAAT GAAGCAACCTTCCTAAGAAGCAGAAGGTCGGCTGAGGTGTGAGCGCAGCTTGCACAAGGC CCCGGACCTCGCTCCTGGTGCCATTAGAATGTAAGAAGTGCCAACCTTCGGCCACCTCAT GCTGGCCCGATGATCTCTGGGCAAGAATAACAAGCCCTGCCTGCTCTGGGGCAGGCTTCT GGGAGCAGGGCAACACCTTCATACAATACACCTTGAGCAAGCTCACACACCTTACCTAGG GCCCACACTGGTTTATAAAACATAGCATGCCACGGGGCCCGTGCACTGGGGAGCACTGAC CAGTGTGATGGCTGATGTCACATGTCAACTTGGCTGTGCCACAGTACCCAGATATCTGGC CAATCATTATTCTTGATACTTCTGTGGAGGTATTACTTTTTTAATGAGATCAACATTTAA AGCAGAGGCTTTGAGTAAAGCAAATGGCCCTCTGTAATGAGGGTGGTCCTCATCCAATCA GCTGAAGGCATGAATAGCACAGGCTGACCTCCCCCAAGGAGAAGAGCAGAAAGTTCTGCC TCCAGACAGCCTTCCATTGAGCTGCAATTCTTCTCTGGGTCTCCAGCCTGCTGTATATTT TAGACTCGTGGCATCTCCACAATCAGGTGAGCCAATTCCTTGTAATGTCTACACACGCAT ACACATGCACACACCCATTAGTTTCACTTCTGTGGGGGACCCTGACCGACACAATCAATC AGGGACATGGCAAAGGTATCACGCCAGGCTCCAGAGATGCCTCCAATCCCCACTTCGGAG CAGAACCTGACTGCGGAAGGAAGCCCCCATGACCACATGGCACCAACAAAAAGTCATGCC TGTGAAGGATCTAGGCACATACACAATATTTGGCTGGGATACTGGGCTGACCTGTCCAGG GATAGGAGAGCCGACATATCTGACCCCAGAGAAACACACCACATCACTGTACTACCATGT CAAATTCTCCCCAGGCCATTTCACTTTAGACAAGCTGGAGGCATGGAGGAGAGTGGGGCG AGTTTTATCTTTTGGCTAAAAATACAACTAAGACTTCCGTAAAATAAGTTCAGTAAGCCT CCTAATGAGAAGAGACTCCTAAATCCAAGAAACTCTCCCAGAATGCAGACTTCCAGCATG CTGTGCACTGCTATTCTGGAACCTATGAGCACACATGTGCAGGCAGGCACTCACACACAC ATGCATATATGCACAAGGTACATGCACGTACACACACACACACACAAATGCTCACACACA TTCACATACACACATGCATGCACCCCCCCACACACACACAAACACACACGGCCTACTAAA ACACTGCCAATTTCATTTTCTGGGCTCCACCATTCACAGGGGCCATCACATGTCCTGCTA ATCAATGCCTTGACAAGAGTAATGTACACCAAGGAAAACAGTCAAGGGTGTGGCAGACTG GAGAGACCTCCACTGAAGGCCCCAGGGACACACAGCACACACAAGGGCACACATGGCTTC GTAGCACACTGCAGAACATACACATCTATGACACAGTGGTGAGCAAATAAAGCAAGGTGC ATACCTCTGCGTGGCATGACCGCGACTTTGGGGAAACACCCCCTCTATGGATGTGTGTGT ACTTATGCATGCACGCATGTGTGTGCATCTGAAAATCGCAGAGAAAAAAATTCAGAAAGG CAGGTTGTTTATGGCATTTACCCAGCACAATGAAAGCGTTCACTCTTTGCTTTCTGTCTT CATTTTCTGAGCAATAAAAATGCCATTAAAATAATGGAAAAGTTAGTCAGCACATCTTAC TTCCTGTTCACACTAAATATCCAACAAGTATTCTTGTAGAAACACTCCTTAAAAGCAAAG GCCCCACCAACAGAGAGAAAAACTCGCATAAAAAAGATAGAAGGCACCTTTCCTGTTTCC CCTCTGAGTCAACATGAAGTTATTTTACGAAGCAGAGAGTTTCCACTGTACTCTTATTTC TACAGCTTCCCACAAAGGCAAAAAGCAGCTGTGGTTTCCATTTTCCTGCTGATAAAGCCC TGCTGAAATATATCCTGGAGAAGGTGAAAGCCTGCCAGCCCTGTCTCCGCCCACCAGGGC CACCAGCTCAGCCCGCGCAGTATTTCAATTGCCTTCTTGTGTGCTGTAACAGGTTGAAGA GATGCAATCTTGTTTGCAAAAAGGGTCTTTCTAGATGTAAGAATCTCAGGATGAGATCTC CCTGGGTTATCTGAGTGGGCCCTAAATCCAGGGACAAGTGCCCTTATAGATACACTCAGA GGGAAAGACAGACGCAGACGCCATGTGATGTTGGAGCAGAGACTGGAGCAATGTGTCACA AGCCAAGGGACACTGGGGCCACACAAGAGGGAAGAAGCAGGACGGAGGCCCCCCTAGAGC CTCAGGGGAGTGTGGCCCTGCTGACACCTTGATTTTTACTTCTGACCTCCAGAACTGGGA GAATAAGTTTCTGTTGTTGGAAACCACCCAGTGTGTGGTACTTTTTATGGCAGCTACCAG ACATTCATCCCTATGTCCCCTGTGCGCCTATGAAAAGGGATTGTTTCCTTCATGGTTCAT TTACAGAGAAAGCAAGAAAGCCCCCAATACACAGACTATGAAAATGTGCGGAATGAGATG AAATGAATCATCCTCACTGCACCCTTGTTAGGGGTCTGCCTCTTGTTCACACTCCACTCT CCCACCCAAAACCTGAGTCCTATGGCCCCCTCATCCTCCACCCCACCCCACCCCACCCCA AGGCCCTTCCTTCCCCCTCCTTGGGCAGCCACCGCTTTTGTTCCTGTCACTGCTGCTGTG TTGCATGTTACCCTGAACTCAGCAGCCTGCAACATGTTACTACACTCCCAATTCTGTGGG TGAGGAGCCTCAGCGGGCCCCAGCTTCAGTCAGCTCATCTCTGCTCCAATGTCCAAGGAC ACCAAAGCTGACACACCTAATTACCAAGGGCTACAGCTACAGTCCTTGGAAGGCCTGTCC CCTCACTTATCAGGGCCCTGAGTGGAGGGGACTGAATACCAGGGCTGCCCACTGGAGCTC CCATGGCTGCCTGTGGAGCTTGGGTTTCCTCACAGCATGGCTGCCAAAGGGCCAACTCCT TCCTTGGCATCACAGGGCTCCCAGAGCCAGCATCCTGGTGAACAATGGGGAAGCCACATT GGGGGTCACTCAGCCTCACACCCACCACATTCCACCAATCAAGGCAGTCAGGAAGTAACC CAGATCCACAGCAAGGGGACAGACACCCTGCATCTCAGTGGCAGCAATGGCGAGATTGGC CACCATGTTTTAAAAACTACAGCTTTTCGCCCAGCTCAGCCACCAGCTGTTTCCGATTTG CTCTGAGTTCTAACTCAGTGTTTGTTACTTCAACACCTCAGCCCCGTCCTCGTTGGGCAG CCTCACCCTCAAGATCCCCTCAAAGCCCCTGTATCCCCTATTGTGTCCGGAATTGGTGGG TTCTTGGTCTCACTGACTTCAAGAATGAAGCCGTGGACCCTCGCGGTGAGTGTTACAGCT CTTACGGTGGCGCGTCTGGAGTCTGTCCCTTCTGATGTTCAGATGTGTTCAGAGTTTCTT CCTTCTGGTGGGTTCGTGGTCTCGCTGGCTCGGGAGTGAAGCTGCAGACCTTCACGGTGA GTGTTACAGCTCTTAAGGCAGCGCGTCTGGAGTTGTTCGTTCCTCCCGGTGGGCTCGTGG TCTCGCTGGGCTCAGGAGTGAAGCTGCAGATCTTCGCGGTGAGTGTTACAGCTCATAAAA GCAGCGTGGACCCAAAGAGCTAGCAGTAGCAAGAGCGAAAGAACAAAGCTTCCACAGTGT GGAAGGGGACCCGAGCGGGTTGCCAATGCTGGCTCGGGCAGCCTGCTTTTATTCTCTTAT CTGGCCCCACCCACATCCTGCTGATTGGTAGAGCCGAGTGGCCTGTTTTGTCAGGGCGCT GATTGGTGCGTTTACAATCCCTGAGCTAGATAGAAAGGTTCTCCACGTCCCCATCAGATT AGTTAGATACAGAGTTTCCACACACAGGTTCTCCAAGGCCCCACCAGAGCAGCTAGATAC AGAGTGTCGATTGGTGCACTCACAAACCTTGAGCTAAACACAGGGTGCTGATTGGTGTAT TTACAATCCCTGAGCTAGATATAAAGGTTCTCCACGTCCTCACCAGAGCAGCTAGATACA GAGTGTCGATTGGTGCACTCACAAACCTTGAGCTAAACACAGGGTGCTGATTGGTGTATT TACAATCCCTGAGCTAGATATAAAGACTCTCCACGTCCCCACCAGACTCAGGAGCCCAGC TGGTTTCACCTAGTGGATCCCGCACCGGGGCTGCAGGTGGAGCTGCCTGCCAGTCCTGTG CCGTGCGCTCGCATTCCTCAGCCCTTGGGTGGTCGATGGGACTGGGCGCCGTGGAGCAGG GGGTGGCTCTCGTCGGGGAGGCTCGGGCCGCACAGGAGCCCATGGAGTGGGTGGGAGGCT CAGGCATGGCGGGCTGCAGGTCCCGAGCCCTGCCCCGTGGGAAGGCAGTCAAGGCCCGGT GAGAAATCGAGCACAGCGCCGGTGGGCCAGCACTGCTGGGGGACTCAGTACACCCTCCGC AGCCACTGGCCCGGGTGCTAAGTCCCCCATTGCCCGGGGCCAGAAGGGCTGGCTGGCTGC TCCGAGTGCGGGGCCCACCAAGCCCACGCCCACCCGGAACTCCAGCTGGCCCGCAAGTGC CGCACACAGCCCCTGTTCCCGCTCCTGCCTCTCCCTCCACACCTCCCTACAAACTGGGGG AGTGGGCTCCGGCCTTGGCCAGCCCAGAAAGGGGCTCCCACAGTGCAGTGGGGGACTGAA GTGCTCCTCAAATGCCGCCAAAGTGGGAGCCCAGGCAGGGGAGGTGCCGAGAGCAAGCGA GGGCTCTGAGGACTGCTAGCACGCTGTCACCTCTCACTATCAGTACATACACACATCCTT CTCCCGCTAAAAGTAACACGTCTTGTCCATTCTCCTCCAACCCCCAACCTCTCACTGCCA TCCCAGAACCTGGGACACACTAGGCAGGCACTGCATGCTCTCCGAGGGGTAGATGGCAGC AGATTGAGTGGACCCTGTGCAGCCAGAGACAGAAACTGTGAAGCTGAAAAACACCATGTT AGGAATGACAGGGACGTGCCCACCTGGCCTTGGTGAGCAGGTGGCGGTGGGGTGGGATGC ACAGAGGGGACAGCTGGAGAGACCCCCGAGGGTCCAGCGAGGGAGGCGGGGCCCATCAGC AAGCAACAGGAGCTGGTTCAGGGGCCCCTTCTCAGAGGAGAGGGTTCACAGCAGGACTGG AAACAGGGTGCCACGTGGGAGGTCTGAGACAAAATTAAACCACAGGTGCCACCACGGAGA CAAGACCTGCCCCAGGAAGTGGAGCCATAAGAACTGGAGGGCCCTTGGTGTCCTGAAAGG ACAATAAAAGGCTAAAACACAGCCTGTGTGCAAGGATGTTCAAAATATCATTCCTAACAG CCTCAAACTGGAAGCCGAGAGGGCAGCAGACACCCGTGGCGGATATAAATGTGCCTAAAT TGTGGCAGACACACACACCGGAATACGTGGTGGCAAGGCAAGAGAAGAAGACCCTGGGTG AGCTCAAGCCAAATGTCACAGACGGATGCTGAGTGACACGCACGAGGATGTGCTGCAGAA CCCAAGGCACACAGACTCAAGCCAGCCAAGATTAACCTGCGCTGTGATCAGCTGGGGAGT GGTGAGCAGGGGGCCCCAGGGCCCTGTGCTCTGCTCCTCTTCCCAGGCATCGCAGGGCTG GCTCCATTTGTGAAGATTCAAGGGCCGCACACTGAGGCTAGGTGTGCTTCACAGTAAATT CTGCAAATATCTCACTGCAGAAGGAAGGAGGAGATGGAAAGATGAAAACAGCAAACCTGG TGAGAGGGTTTCGCTGCTGCTGCTTCCTGTCGATGACCTTCCCTTGACTCCAAGAGGGGA AAGGAGGCAGGGAGAGGGGTCACCGCCCAGACGGGTGAGGGGATCCACTGCAAAGTAGTG GGCCATGGAGCCGACCCAGCTGCTCTAAGAAGAAGGCAGCAAAGCCAGTTGAGGACCAAC CAGCTCACAGCGGTCAGAGCACTTGCAATGTCCACCATCCACTGGCTGGCTGTATCCTAC TGCCCTCCTGGGACACGTCCACAGAGAATGTGCACCAGCAAGGCCACCAAGCAGGCCACA CCTGGATCACTCTGACGACCACGAGGCCAGAGTCTCAGACCATGGAATCTGCTCTTCATG TCAGCTCTGATCAGACAGGCACTTGGAAGAGTCACAACGCAAAGAACAGCACGGGCCACA CTCGTTACGGTTTACACAGGCATCAGCAACAGCTCTGATCCTCAGGGAAGCCTCCCAGCC ATTCTCAGCCCCAGCAGCAGAAGGCCCCGCAAAGCTCAGGATAACTGCACTGTAGCAAAT GTCTCCTGTGCAGCAGGAGGCACACTCTGCCTCCTCCAGCAGCAAGGAGAGGGCCCCCAG CCCAGCAGTTTGGGGAGGGTGACACCAGCAGGAACGGACTCCCGGCCTGACACAATTCAT GAATAAGGCTGTGCTTGGCAAAGTGTTTTTCCGTCTGTAGCAACTACAATGTAAGTGCTT GAAAAGGCTTCAGAGTAGTCCTGACACAAAATGTCTCAGTGGAAGTCTCCAGATGACACC ATCACTTATTTAGAGAATGCCACTGTGGCCTGAGCATGGTCTCCTCGCTGAGAAAAGAGA AAGGGGAGAGAGCATGTCTGCATTCTCAGGGCTCCTTCATTTCCACCGCGAGACATCTGT GCTAAGCCATCTATCCCTTCTGCAGCCCTAAATGTGCTAATTATTAAATGACACTCTCTT CCAGTTGAAATAAAACCTGTGCCCACTGGCTGGAGTCACAGAGCGGTTACTTGTAAATAA ATGGAGTCTGTATCTCCCCGAAGGCTTGATTCCAGGTCCTGCAGCGACTGGTGTCTATTT TAAAAATCGCCTTCTCACCACCTCTCTGGTTTCGCCAAGCTGGCAAAAACCAAGCCCTGC TCCAACCGTGCTCTTGTGGAAGGAACTGGAACATGAGGATGGCAGATCCCTGCACAGAGA GACCTCAGCCCCACAGAACATCCAGGACGCAGCCGCTGCTTACAGGCAAGACCAAGGGAG CCAGGCGGCTTCCCAGGATTCCACATTTGAAACCCAAGCCACTGCCCTCAGCATTCAAAG ACAAGCTAGATATCCAATTCCACCTGCTCAAGAGCTCTGCTTTGACCCAGTTTTCCTGCC CTGTTGTTCTCAGGCTTGCGGTCCAACACCAGCCCCTGGGGTAGGCACTGTGCTGAAGGC TCTAAGGCATGTCCAGCCCCAGAAATGTGGGGATTAGCCTCACTGAGAGGAAAATCAAGC GGTAGAGGAGTACATGGTCAAAGTCAGCCAACGTGAGAAATAAGATAATAATACATAGTG TACACACATTGACGTCACGCTAAAATTTTTACATTTCCATGCAGTTACACATAGGGCCAG ATGTCACATGGGGGTCAGTAGTTCTCAATCTGGGGGTTGCAAACACAGTTTTTCAACAAA TATAATCAAATAAAAATATCAGGGGGTGTCACAGATAGTTAAGGGCGGCTGTTATGAGCA AAACTTACTGGCATGTGTGCATCTGTGTGCTGTGTGTGTGTGCGTGTGCTGCCTCACAAT ATAAAATGCATGTGGGTCACTGTCAGCGTCTGAAGCCAGCCAGGCATGAGACACCCACAC AGCCAGGCTGCCTGATGGTCAAGAAGCTTTTGTATTGTAATAAAAAATGTTTTAGCAATA TGGTCCATGCACTGAAACCTTCCTGAGGCTTGGTTTCAAACATAACACTGAATTCCACAT GCATCTCAGTTCAAACGTGGGCAAGAAGGGATATTACAGGAGTCATCTCATTTAATAATC CTACAGTCCCCCAACAACCACTGAGGGACAACCCCACTAAGGAAGAGGGCGGGCCCCACT GAGGCTGCGCACAAGCTGGCAGGCACAGAAGGGCTTCCGGGCTCCCCCAGGAACTGGAGC CTTAAAGAGGACGCCGCGGCCACCCCGCCCTGCAGGCCCACCTGCAGCTGGGCTGCATCT GGGAGAGGCAAGCGAGGGGCCGGCCAGCTTCACTGCCTGCATGCCCTTTAGGAGCAGAAC AAGCTGCAAAACACCCACCTGCTCTGGGAACAAGGCACGCATGACCAGTCTAGGAAAAGT GTGCAAAGCTCTCAAGACTCCGATGCATACGGGGTATGTGTGTGCTGTGTGTGCTGCGGC ACGTGCAGCATATGACTGTGTGGTGTTATGTGTGGGGTTTGATGTGTGGTGTGTGTGGTG TGTATGTGTACAGTGTGTGTTGTGTGTGTTTTGTGTGTGTGTGTGGCATGGTATGTGTAT GTACCACGTGGTGGGTTTGTGTAGTGTGTGTGGTGTGTATGGACTGGGTGTGTGGGGTGG GGAGGTACGTGTATGGTGTGTGTATACATGGTGGGGTATGTGTGTAGTATGGGGTGTTCC GTGGTGTGATGTGCGGTGTATGTATGCAGTATATATGTAGTGTGTGTGTGGTGTGGTGTG TGTATGTAGTGTGGTGGCTGTGTGTGTGGTATGTGATGTGGTGTATGGATGTGTTGTGTG TTATGTGTGTGTGGTGTGGCAGGTATGTGTGAAGTGTGTGGTATGGGGAATGTGTGGTGT GGTGTGTGGATGTATTGTGTGGTGGGTGTGTGGTGTGTGGATGTATTGTGTGGTGTGTGT GTAATGTGTGTATACTGGGTGTTTGTGGTGTGGGGGGTATGTGTGTAGTGTGTGGTATGG GGTGTGTGGTGTGATGTGTATGTGTGTGTTGTTTGGTGTGTGTGTACTGGGTGGGTGGTG GAGGCATATGTGTGTAGTATGTTGTGTGTGTGTGTGTGTGTGTGTTCCAGAGCTACATTT TTCAACCTTTTCCTTTGTATTTCTCCTTTGTGATTTCCATAACAAGTATTGTTGCAGAAA ATCAGAGAAATGTAGACAAGCACCAAGGAGAAAACAGAAGGCACGTCATCAACTAAACAT CTGACTCGCATTTTGGACATGGTCTAGTGCTTTCTAGGCAATTGTAAGTCCTTGCCATGC ATGTTGGTTCACAAACTGTTCTTAACACATGATGTATTATGCTGACTTCTCATCTCATTA GGCATATTTTACACTAGATTTTCAAAGAGTGACCAATGTTACTATGGCACATCCTGCCTA ACTATTTCACTGTCAGTAGCTGCCCAGGTTATATCTGGATTTTCTATTTATAAACACTGA GAAACACCCTTTTCAATAAATGCTTCTTAACATTCATGATTCTTTAAATAAATGTCTAGC TCATTCAGACTCCAATGGCCAAAGGGTACATGTGCCTTAAAATCTTTAAAACATTAACCG GGCTGGGCACGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCAAGACGGGAGGA TCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACT AAAAATACAAAATTAGCCGGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAGG CTGAGGCAGGAGAATCACTTGAACTTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCAC CATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAAAAAA AAAAAAAAGAAAAAAAAAAAACCACTAACCAACTGCCACCTCCTAGTGCATGCATTAGAT GCTGGACCTCAGTATAGAGCATCGAATCACAACTCCTGGCTTCACCACTTCTTGGCTGAG CGGCTTCAAGAATAACATTCTTATTCTCTCTGTTCTCACCTGTAAACAAGAGGGGAGAAC TGACCCAGTCTTACAGGACTGTGGTCAGAACTCCATGAGACGGATAGAGTTTGGCATATC ATTTATAACAAGGTCACCATGAACGTCATCTAGCATTCTTGTCCCATAACTTCTTTCCCT TGTTTCCAATCTGTCTTTCCAATTCATCACTCTGAAATGCCAGAGTTACTCCTGAGACAT CGATCTGATTGCTTTATTTACTGCTCAAATACCTGCATAATTATGCTGAGTGAAAGAAGC CAGACTCAAAGGCTACAATCTGTATAATTCCTTCTATATGAAATTCTGGAAAAGCCTAGA GGGATGGAAAACAGGTCAGTGGTTGCTAGGTCTGGGGAAAGGAAACTGACTACAAAGGGG CACAAGACGGAATTTTTGGAGTTATGAAAATTTTCCATACCTTGATTTGGTGTGGAAATG ATTTGGTATGGTTATATTTACCAAAACCACATGCATTAACCAAAACTCACAGAATGGTAC ATTTAACAGGAAAGATTTCACTGTATATAAAATTATAGCTCAATAAATCACACAAATAAC CAGAACTGACTCAAACAGAAACAGAAAATCTTCATAGTCCTATGTTAAGGAATTGAATTC ATAATTAAAAGCCTCTCCATAAAGAAAACCCCAGACAGGCTGGGCACAGTGGCTCACACC TGTAAGCTCAGCACTTCAGAAGGCCAAAGCGGGAAGATGGCTTGAGGTTAGGAATTCAAG GCCAGCCTGGGAATCATAGTGAAACTCTGTCTCTGCTAAAATTCAAAAAAATTAGCCAGG CATAGTGGTGTATGCTTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAAGATCACTTG AGCCCAGGAAGTCAAGGCTGCAGTGAGCTATGATTGAGCTATGATTGTACCACTGCACTC CAGCCTGGACAACACAGTGAGACCTTGTCTCCAAAAAGGGAAAGGAAGGGAAGGGGAGGG GAGGGCAAGAGAAGCCCAATCCTACAAAGACTATTCAAAAATAGTAAGAGGAACCACTTC TCAAATCATTGTGTGGGGCAAACTTTACTTTGATACCAATATAAAATACAGTACCAGAAA AGAAAACAATATCCCTCATGACATAGCCACAAATATCCTTAATAAAATTGCAGCAAATCA AATCCAGCAATATATAAATATATATATATAATATATAAAACAAATATATAAAAAAGATAC ATAATTACCAAGTGGGATTTGTGCCAGAAATGCAAGAATGATTTAACATTCAAAAGTTAA CCAGTGTAATTCACCATATTTACAAACAAAAAATGAAAAACCCTATGATCATCTCAACAG ATACAGAAAAAGTATATGAGGAAATTCAACACCTACTCATGATAAAAGCTCTCAACAAAT TAAAAAACTTCCACCGCCTTGTAAAAGGCACTTCATATCTTTACCTAACATCATACTTAA CAACAACAACAACAAAACTTGAAATTCTTCCTTCCTGATATTGGGAACAGGCAAGAATGT CCACTTTTATCACTTCTATTAATCATTGTACTGAAAGTCCTAGAAGTGAAAGAAAAGAAG AAAAAGGAGTAAAAGGCATTCTAACTGGAAAGAAACTGGTCTTTATTCATAATCATCAGA ATTATCTATATGAAAGATCTTGAGGGACTACAAAAAAAGCTACTTAAATAGCGACTTAGC AAGGTTCACAGGATAAACAAAAAATAGAAAAAATCAATTGTATTTCTATATATCGCAATT AACAACTGGAAAATAAAATTTTTAAAATCCATGTATAATAATATGAAATACTTATGAGTA AATCTGATAAAACATGTGCAAGACCTGTACACTCAAAACTACAAAACACTGCTGAAAGAA ATAAAGGAAGATGAAAATAGAGGGAGATTCCATGCTCATTGGTCAAGAGACCAAATATTG TTACAATGTTTTTTCCCAAATTGATCTAAGGAGTTAATACAATTCTGGCCAAAATCCAAG CAGGCTTGCTGTAGAAACTGACAAACTGATCTTAAGTATATAAGAAAATGCAAAGGATCT AGAACCGACACTACAATTTTGAAAATGAAGCAAAATTGTCATGCTACCTGACTTCAGGAG TTACTACAGAGACAGTGTGATACTGGGACCTATGAGGAATAAGCCATAATGGAACAGAAC AGAATCCAGAAACAAAGGCACACAGATATGGTCAATTACTTTACAAACATGGTATCAACA TAATTCACTGGAGAAAGAAGAGGCTTGCTGTTGTTGTTTACTTTAAAACAAATGGTGTGA GAACAATCGGAAGTCTACATGTAAAACAATGAACCTCAATCCTTAGCTCTTTCCATTAAA AATTAACTCGAAATGGATCACAGATCTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGAAC AGAGTCTCACTCTGTCACACAGGCTGGAGTGGCTGGAGTGCAATGGTGCGATCTCAGCTC ATTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGGCTCCCAAGAAGCTG GGATTACATACGTGCACCATCACATCCGGCTAATTTTTGTACTTTTAGTAGAGACAGGGT TTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGTTCCACTCACCTCAG CCTCCCGAACTGTTGGGATTACAGGCGTGAGCCACCACGCCCAACCAAAATGGATCTCAG ATCTAAACATAAAAGCTAAAATTACCACATTTTCAGAAGAAAACACAGATAATCTTTATC ACTATGGATTAGACAAAGATTTCTTAAATAGGGTACAAAAAGCACAAACCATTAAAACAA CTTAAAACCAAAAAGTCTGCCCATTGAAAGATATAACGGATAAAAAGGCAAGCCATAGAC TGAGAGAAAATATTTGCAATACAAGTATCTGACAAAAGGTTTGAGTCAAGAATATGTAAA GAACACCTACAACTCACATATAAGAAGACAACCCAATTAAAAAGTGATCAAAAGATCTGA ACAGACACTTCACAAAAGAATATACACAAATAGCTAATAAGCACATGAAAAGACGCTCAA CTAAAACTGCACAGATACAGCACTACCACATTTCCACTAGAATAGCTAAAATTAATAAGA CTGACAACAGCAAGTGTTGGCACAGACGTAAACCAACTGCAACTCTCATGCGTTAGCAGT GGGAACGTAAAATGATACAACTGCTTTGCAAAGCAGTTTGCCAGATTTTTAATCAAGTTA AACATCTACTTACCATGAAACCCTGTAATTCCACTTGTAGGTAGTTACGCAGGAGAAATA AAAACATATGTCCACGCTAAGATTTGCCCACGAATGCTCACAGCATGTCTTATATCATCT TTTATTGTGGTAAAATACTCGTAAGATAAAATTTACCATTTTAAAGCGTATAATCCAGTG GCATTTAGTACATTCGCAATGTTATGTAACCATCACCCCTATCTAGTTCCAGGACCTCAA AAGGAACCCCAATGCATATTAAGTGTTCACTTCCCATTCCCCCACCTCCCCAGCTCCTGG CAACCACTAACGTGTTTTCTGTCTGGAAAGATCTGCCCATTCTGAACATTTCATATCAAT GAAATAATACAATATGCAGCTATTAATCTGTGCCTGGCTACCTTCACTTAGAATAATGTT TTTGAGGTGAATTCACATTGTAGCATGTATCAGCGCTTCACTCCTTTTTATGGCTGAATC ATAGGCCATGTATGAATATACCACATTTAGCTTACCCATTCATCCACTGCTGGACATCTG GGTTTCCGTCCTTTGGCTACTGGAATAGTGCCACTGTGAACAGCCGTGTATAAGTTTTTG TGTGAGTCCCTGCTTTCAATTCTTTTAGGTATATACGTAGGAGTGGGAGTGCTAGGTCAT ATGGTAATTCTGTATTTAACTTTTTGAGGAATCTCCAAACTTTTTTCCAAAACAGCTACA CCATTTTACATTTCTATCCGGAGTGTATGAGGGTTCTAATTTCTCCATAACCTCACCTAC GCTTGTTATTTCCCTCCACCCTCCTTTTTTTTTTTTTAATTAAAGCTAGTAGGGTGCGAG ATGGTATCTCACTGTGGCTTTGATTCACATTTCCCTAACAACTAATGATGTTAAGCACCT TCTCGCATGTTTATTGGCCGTTTGTAAATCACCTTTATTGACACATTTACCCATGTTTTA ACTGGCAGTTTTTGTGGTTGAGTTGTAGCTCCCAGCACTTTGATTCACAATAAACCCAGA AGAGGAAACAATTCAAACTTCCACCAACTATTCAGCAATAAAAAGACATCAAGTGCCGGT ATGCACAGCAACATGTAAGAATCTAAAAAACATTATGCAGAGTGAAAGGAGCTAGACAAA AGAGTATGCAGATGGTCCCCCATTTACAATGGTTTCATTTATGATTTTTTGGCTTTACAA TGGTGTGAAAGCCATTCGAATCCAGTAGAAACGGTACTGCGAGTATCCACACAACCATTC TGCTTTTCACTGTCAGTGTGGCATTCAATAAATTATATTCAACACTTTATTATAAAAAAG GCTTTGTGTTAGATGACTCTGCCCAACGGTAGGCTAATATAAGTGTTCTGTGCACGCTGA AGGTGGGCTAGCCTAAGGTATGCTTTTGGGCGGGTCAGGTGTATCAAACACATTTTTGAC TTAGGATATCTTCAACTTAATGATGGGTTTATGATTAGGATGTAATCCCATCACAGGTCT AGGAGCAACTGTCAAATATATGCTCCCACTTTGAAAGTATTGAAGAAATAAATCCAATCT ATAATAATCTAATCTATGCAGATCAGTAATTGCTGGGAAGAGGGGGTTGAGTGAAAAGGG GCAACAGGGAAATTTAGGGGGATTCTCAGGGCCATATGGTCTCTGTGGCAACTGCTCACC TCTGCTGCAATAGCATAAAAGCAGCCACAGATGATTCGAAATAAATTGGCCCAGCACACT TGACCTGCAGGCCCAAGCTTACCAAATCCTGGTCTATATCCTGATTATGGTGTCAGTCAC ATGGCTATCTACATGTGTCAAAACTCAGTTAGCTGTGTTTGAAGTGAATACATTTTGTCA TAATTCATGTCAATAAAACTGAGTAGGACAGCATTGCCTCTAGTGGGACTCCACGTGGAA AGCACCCCAAGTCTAAGGTGCATCCAACCTGGGGACCGCTACTTTCTCCCCATGGGCCTG TCCCACCCACTCCCAAGTGTGGGCCTGTCTTAGGGCAGCAGTTCAAAAGCCTCTGGGGAG CCTGTTAAAACAGATGGCTGAGTCTGGGCACCGTGGCTCACACCTGTAATCCCAGCACTT TGGGAGGCCGAGGAGGGTGGATCACCTGAGCTCAGGAGATCGAGACCATCCTGGCCAACA TGGTGAAACGCTGTCTCTACTAAAATACAAAAAATTAGCCGGGCATGGTGGCGTGTGCCT GTAGTCCCAGCTACTCAGGAGGCTGACGCAGGTGAATGGCTTGAACCCACGAGGCAGAGG TTGCAGTGAGCTGAGATCACACCACTGCATGCCAGCCTGGCGACAGAGCAAGACTCTGTC TCAAAAACAACAACAACAACAACAACAACAACAAACAGATGGCTGGTCCCACCCCACAGT TCCAGATGCCAGGGAGACTCTGCATTTCCCAGGGGTGCAATGCCGCTGGTGCGGGGACCA CTCTCAGAGAAGCACACTCCCATTCCTCCAGCGTTCAGTCCATGTGGAACTGAGAGTCAG TGTTGCAGGCAAAATGCAGGCCATCCCTGCCCGGCCTGGAGACAATGCCAGCACTCACTA AGGTGATGAGGAAAATGCTCACAGTCCACCAGCGATGGGACAGCCCCATGCATCTGTGGG CCCCGGGGCCAAGAGGAGGCACAGCACACACCGAGAGTCAACAGCAGCTCATGGGGATCC TTCACCAAAGGGGCGGCCCCAGCCAGTCTCTGTCCCTCCCACCCACCTCACGGCTTCCTC CCACTCTGCTCCATCCTTCTCTTCAGGATGCAACCCTTCCAAGCGGGCCTCCCTCAGCCC TATCTGCCCATGACCCCCCTCCACTTCCCCACTGCCCTTCACGGCAGCAAAATTCTTGAA AAAGCAATAGGGTCCTGCTGTCCCAAATTCCCCTCCTTCCTTCTCTCAAGAAACTCACCC CATACTTCAGCCCACCATCCCAGACCACATGGATAAACCCCAGGTTGTCTTCGGTTCTCA CCTTCGTGACCTCCGCTGTCACCCTCCCTCTCATGCAAGCTGCATGTGGCCTCCAGGATG CCCTCAGAACCCTCTGGTTATCCCCTACCTCGCTGGCCGCACCTTCTTGGTTTCTTGTTC CAGGCTCAGTCCTCGGACCTCTTCTCTTTTCCATCTACCTCAACTCCCTAGTGGTCTCAT CCAAACTCCCTTTCAAAATGTCATCTCTATAGCTACAATATATTGCCAAGATTAGGGTCC CAGCTCAGAGCACTCCCCCAAACTCCAGATCCCTTCCTCCAACTTCCTCCTCCCCACCTC CACTGGGACACTTCAGTAGGACTCTCACCTGTACTATCTTGAGAGCCACACCATCCCTCT GAATCCTCACAACTCCTCCCCTGAAGACCTCAGTCTCAGAGTGATGGCAACTCTACCCTT CCAACACCCGATCCAAGACTCTTGGGTCATCCTGGACCCCTTGCTTGCTGCAACAGCCCT CATGGGATCCATCACAGTCCTGTTGGCTCCGTCTTCGCAGAACACCTGCAATCAGCCTGC CTCCCACCCGAGGAGACTGCCCGAGCTCCTGCAAGGCCCGCCCCGCACCGCCCTCCTACC ATTGCTCATGTGTGCCTAAGTGTCCCCTCACCACTCCTCACCTCCCCTACATCTAGGGCT CAGCAAGGCACAGGGGCCACCTGATTTTAAATCACAACCACCCTCTCAACAAACCACTGG CCCCTTAAGCGGCTGGACCTAGAACTATCTATCTCCCCTCTCATTAGCCTCCCATCTCCC TCCACTTGACCATATTCCCCGGCACCCCAGCCATGACTGACATTCAATACGTGTTTTCTG GGGAAGCAGTGAAACTTCATCAAGTGGACAAGTGCAAGAGTTGGGAGGGCCCTGAAAGGT AAGCAGTTCCTTCAGGTCAGGAACCTAAGACAAAGGAGCATCACCCACCAGGGACCAAAC GTGCCAGCACTGTGACCTGCCCAGATGGCTCAGCTCCTTGTGGGCCCTCAGAAGGAGGGG GCTATACAGGATAAGTGTGATCCAGATGGGGGAAAAGAATGTGCATCCACCCACTGGGTG GTTCTGTGCAGGCGCAAAGGCAGGCGGCTCCTGGCAGCACAACAATGAACATGTGCCAAG ACCCTCAGCCCTCAAAGATGGCCCAGGGCTCAGAGCCCCGCCACAGCCCTGCTGCAGCAC TGGGCTGTGCCCTCACAGCACATGGGACACACCGGTCAGGAACAACAACAAACAAAAGCT CCTAAACTCACAGTGAGAACCAAGTGGGTCAATTGCAGGCCTAACGGGAAACTTTCTGTC CTTCCAAACAAAGTCAAAACACACACACAAATCAGAAGGCCTAACAAACACCCACATTCT ACATCAAGGCAAATTACGTTCTGGCTGCTCAAGCAACTCTAATTTCTTGCAACAGATCAG GAAAATACAAAAACTGTTACAATTCTAAGCAATTTCTACTTTTTACTTTGTAGACTTCTA TGCAGCACGCATCACTTATGTTTTTGCTATAGCTTTAGGTTACTTAACATATCCTTTACT AAATGGAAGAAGAAAACAAAGACACCACAGGAAATGCTGGAACAAGCCCCAGGTCCAGGT CAGCCAACCAGCAATGGGGACCCCTCTGGCGCAGGCTCCAGACCAGACTTGGCCTTTGTT TCTGTACTGAGTGTAAGGATAACCCTTCTGTGGCTGGATTGTACTATTATTTAATTGTCA GGGTCTTTGTCTTGTCTCCCCTAATGCTGATAGTAGCATATTGATTTCTATCCTTCATAG CCCACAAAGCACATATTCAGAGGATCAATAACTATTGATTCATTGATTGCCTCATGGAAG CCAATTCATCTGTTATTAAGACGTGTAGAAACATGAACTTCCACAAATCAAATTCTATTT AAAACGCCAGAGGAAAGTATATGACCTAATGAAGACCACTTTTTGAAAATTCATTTTGAT ATTCCAAAAATAATTCCTTGTAACAGAAACAAACCATACATAAGTACAAAAAGAAGACAA AGTATAGGTTCCCTCTTCCTCTTCCCTCTCCTCCCCCAACACACACTCACTCACATTCAC ACACGCCCCACCCTTTGCTAACTGTGGAGTGCTGCTTTCACTCAGGGCTGAGTCCCTAGA GCCTGGGGCAGCGCCTGGCACCAGGTCCACATAGGCGGCTCCATAATGATCTGCTGAATA CCAGGTGTGTGTCCTTCCAGATGGGCTTCCGTGCTGAGCGCCTGCACTTGTGCATGGAGA GGGCACATTCTCTATAGTCTACACTAAGGAGTGACATTTCTACTTAATAGATTGGCATAT CTTTTAAAGTAAACCTTTGAATGATGCCATCATGAAGTAAAGAATCCAATGGCATGTTTT ACAGGGAGGAATTGGAGATCTCCGATTATTATTAACTTTTCATGATGGAGAATTTTCAAA GTGCATGCAAGTAGGCAGAACAGAACAAAGAACCCAGGTACTCTCATCCAGACCCCAAAC TGTCCACTCAGACCATCTCGCCCCTTCTCATCCCCTCTGCTTCCCCACCCCACACTAATC TGAGGCAGATCCCAAACATCATTTCATCTACCAACACTCAGTATCTATTGCTAAAGGGTG AAAGTTATTCTAACATAACCACGATGCTGTGATTAAGGAATTCCTTAAAATCATCATTCA CTCCACAAATGTCCATGAGACACATCAATAGCCTAGTTTTCAAAGGAGTGATGCTTGGAT CAAATGCTGATCCAAGTGACAGCCTGGATCAGGCTTTGATCGAAGCCAGAAATCTTGGGG TGCCACTTAGATGTGATCCAGGGCAGGGATGCAGTCATTGCTTTCATGGGCAGCATCTGA AACTTCTGGACCAAATAACAGGACCCTGCCTGCCCCCCACTGAGGTTTGCACAGGTGCTG TGGGAAGGCGGCTGCTGATGCCCCAGGGGAAGCAGCAAGGCAGTAGAAAGCTGGGGCCCC TGCTGTGACACCCCCAGCTAAAGGCAAATTCGCTCAGGGAGGGTCACAGAAGCTGAAAAG TGACCCACAAGCAGCAAAGCAATTTGCTTATCCCAAGGATCGCCTTAACTAGTGCACCTA AAACACCACCCAGCTTCCAGGGAAGGCCCTGGCACACCCTCTCCACCTGACTGAATCAGC AGCTATCTCCTCCAGCAGCCCTGGACCCTGGACGGCAATGGTGATGGGGATGGGGATGCA ATGGGCAGGGCTGAGGAACTGCACCTGCCAAGCCCAGGGCGGACCCTGGCCCAGGGAAGA GAGGACCCACCCCAGCTGCCTCTGCCACCTCCCTTCTCACCTTCTAGTCTTCTTCCTGGA ATTGTCCAAGTTCAAAGAAGAAATAACTGCCCTGGTTGGGAACAGCAGGCAGCAGCCTTT CTCTCAGCAACTAGGCTCGACAATCAGCCGACGGCACGTTTATTTCTATATTTTCACGTG GCAAGTTTCATCCCCATGGGTCCTAGCTCCAACCCTGGAGCTCTGGCTCCAGGGGTCAGG AGGAGAATCTGCAACCACCCTCCTGGACCCGCCCATCCCTCCCTCCCCAACAGAAATGGA ACCAAGAGAGGCAGAAGCCTGAACAGCCTCAATGCAGAAGCACAGAAGATAGAGAAAACC ATTGATCTTTGCAATGCATTATTGATTTTGCTGTTGTGCTGTCAGCAGCGGACGTTCCCT CCCTCCTCAGTCAAAGCTGGCCATTAGCGTGCACTCCCAAGCTTTGGCCTAGACACACCC GCTTGGTGTGGGGAAAGCGGCTCTAGGTAACATCTGCCTCCAGCGGTCCACATGGAGAGG ACTGTCCACAAGTGGATGATGTCACCAAGGACATCTCCCTGGCCCCAGACCCACTGGATA TCAAATGCAACATGGTCGCTGGTCTTGCACTCTAAACCTCAGCCCAGGACCCCAGGCACT CAGGGGGGTCTGTGCAAGGCTGCATTTTCAACAGACTCTGGGTGTGCTTCTCAGGAGGTG GGCCCCCTCCCATGGAGTCCCTCCCTTGTGCTGTGCTGCAAGACCTTGGGCTGGCATGGC AGCTGGGGCTCTGCATCCCCACGGTGGCCTTTTGCCTGTCTGCACTCTGAAATACAGCCA CTGAGTTCCACCGTCTACCAACTCCTAAGCGGCCCACCCTCCTGGGACCCCAGGGCTGCT CCTGGCACCAGTGATGTGTTTCTATTTCTTTGTTTGACTCGCTGAGTGTACCACGTACAC TCTTCTCAGTCTGAAGGTCTGGCCTTATGGGAGGGCAGTCTTTGCTCACAGAAACAGGCC AGTGCATCCCTCATCTTCCCACCCCAGCCTCCCTGGTGGGTATGCTGAGCCCGCCTGCTT TCTTCTTCTGGCTGACGACTACCAAGACATGATATACGCAGACACCAACTGTCAAAATGA CAATCAGGGCATTATCATCTCTACCAGAATCCTGCCCCTGCACTGGCCAGAGCTGCCTGT TTCTGGGACACAGTAAACATTCCCAAATAACCTCGCCTGGGCAGCCAGCAGGCAGGCCCC AGGCCTAGGACACATATGAGGTGACAGGCCACTGGTGTCACGTCACCCCCAGGAAAGGAA ACTTCCGTTCCGTGGCGCCTGGTGGATTTGAAAAGACTCAGAACAGCAGGGTGAGATGCT TGGCCCCAGGCCCCACGTCCAGCTTGGCCTTCGGGGGCCTGGCCACCCACGAGCCTGGGA TGTGCTCAACACAGAGTGAGGTTTTCAAAACAAAAGCAAAGCAACTTCATGTGGAAAACC TTCCGGAAAGCAGGACCCAGCCCTCGACACCAGGCCTCATTTGACGCAAACTGCCCACTT ACAGACTCCCATTCACCCACTCTCCCACCTACCCCCCAAAATACTAAGCCAGAAAATAGA GGACAACCACGAGTTCAACTCTCCTTTACACGTTTTTACTGGCATAACCCCAGTAGAGCC AGCCCCTTGCAGCTCACTAGGCGGCTGCAACAGGTGCAGCCCAAGCTAAGGCTTGTGGTT CTCCTGGGCTGTTCTAGAATAATGCAACCAAAACCCGAAAGGAAACCGAGGCCTGCAGCA CTCACTGCCAAGGCGGCGACCTGACCACTGCGGCCCAACCTGCCCCACCTGTCTGAGTGC GCGGCGCCGGGTCCAGTGCACAGGGTCCGCGGCCTCCGCGACCAAAATAGAAGCCCGCGG GGGCCCGGCCAGAGCCCGGCTGGCCGGAGTGGGGCCTGACCTGGCGGGGCCGGACTGGGC GGGCCGGGGCGCGACGGGGCCTGGCCGAGCGCACCGCCCCCTCCCTGGCCCGGGTATGCA GCGCGCCCCCGCTCCCCCGCGCCCAGAGGAGCCACCTGCGCGCAGGGACTGGGGAGGCAA CCGGGAAGGGGAGAAGGCCGGGGAGGGATAGCAGAGAGGTCCAGGGGGTCGGAGGGGTCC GGGTAGGTGTCTCTGGGAGGCGTCCCAGGAGGGGCCCCGGGGGGATCCAGGAAGGAGTCC AGGGGTCCGGGGATCCCAGAAGGAGGCTCCTGCAGGGGTTCGGGGAGGGCCCCGAGGGTC CGGTGAGGAGCCTAGGGGTGTGGAGTGGGGGCTCCGCGGAGGGTCCAGGCCGCCCCCAGC GCACCTGCCCGGCCCCGCGCGCCCTCCCTCCCGCGCCAGCCCGGCCGCTTACCTGCAGCG CGCGTCCTGCCCGCGGCGGCTCCCGGCCGGGCGAGTTCGGGCGCCAGGAATGGCGGCGGC GGCGGCGGCGGCAGCGGCGGGAGGCGGCCGGGCCGGGGAGGGGGTGGCGGGGAGGCCCGG CGGCGGCAGCGGCGGCTGGGATGCTGCGGCGCGCGAGAGCGCTGAGGCCGGCGCGGGGAC GGAGTGCGCGGGGCGGGCGCGCAGGCCCCTCCTCCGCTCCCCCT bcftools-1.21/test/csq/ENST00000420670/ENST00000420670.fa.fai000066400000000000000000000000221467060157400215170ustar00rootroot000000000000009 137384 23 60 61 bcftools-1.21/test/csq/ENST00000420670/ENST00000420670.gff000066400000000000000000000032571467060157400211520ustar00rootroot000000000000009 ensembl_havana gene 21 137364 . - . ID=gene:ENSG00000187764;Name=SEMA4D;biotype=protein_coding;description=sema domain%2C immunoglobulin domain (Ig)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 4D [Source:HGNC Symbol%3BAcc:10732];gene_id=ENSG00000187764;logic_name=ensembl_havana_gene;version=7 9 ensembl_havana transcript 44688 136666 . - . ID=transcript:ENST00000420670;Parent=gene:ENSG00000187764;Name=SEMA4D-015;biotype=protein_coding;havana_transcript=OTTHUMT00000342408;havana_version=1;transcript_id=ENST00000420670;version=1 9 havana CDS 44688 44690 . - 0 ID=CDS:ENSP00000405652;Parent=transcript:ENST00000420670;protein_id=ENSP00000405652 9 havana exon 44688 44933 . - . Parent=transcript:ENST00000420670;Name=ENSE00001755185;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001755185;rank=4;version=1 9 havana five_prime_UTR 44691 44933 . - . Parent=transcript:ENST00000420670 9 havana exon 57290 57352 . - . Parent=transcript:ENST00000420670;Name=ENSE00001419415;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001419415;rank=3;version=1 9 havana five_prime_UTR 57290 57352 . - . Parent=transcript:ENST00000420670 9 havana exon 95122 95187 . - . Parent=transcript:ENST00000420670;Name=ENSE00001424804;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001424804;rank=2;version=1 9 havana five_prime_UTR 95122 95187 . - . Parent=transcript:ENST00000420670 9 havana exon 136609 136666 . - . Parent=transcript:ENST00000420670;Name=ENSE00001692264;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001692264;rank=1;version=1 9 havana five_prime_UTR 136609 136666 . - . Parent=transcript:ENST00000420670 bcftools-1.21/test/csq/ENST00000420670/segfault.txt000066400000000000000000000000311467060157400212100ustar00rootroot0000000000000044688 C . . 44688 C . . bcftools-1.21/test/csq/ENST00000420670/segfault.vcf000066400000000000000000000005121467060157400211530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 9 44688 . C . . . EXP=. bcftools-1.21/test/csq/ENST00000420670/start-stop-lost.txt000066400000000000000000000002251467060157400225020ustar00rootroot0000000000000044688 C T missense|SEMA4D|ENST00000420670|protein_coding|-|1M>1I|44688C>T 44688 C T missense|SEMA4D|ENST00000420670|protein_coding|-|1M>1I|44688C>T bcftools-1.21/test/csq/ENST00000420670/start-stop-lost.vcf000066400000000000000000000007331467060157400224450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 9 44688 . C T . . EXP=missense|SEMA4D|ENST00000420670|protein_coding|-|1M>1I|44688C>T;type=ENST00000420670:92020369-C-T, this cannot be real, transcript has only one aa bcftools-1.21/test/csq/ENST00000422159/000077500000000000000000000000001467060157400166475ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000422159/ENST00000422159.fa000066400000000000000000001065021467060157400210030ustar00rootroot00000000000000>3 3:10285567-10321112 TGCTTGAGTGAGCTGGTGTGATTAGGTTTTCTAAACATGCACATTGGCCTTGCTACTTGT CCTTTTATTCCCTTCCCACAGACCATAAACCAAGAATTATTTTTATTTGTATTATTTTGA TTTTTTTAAAGTAAAATATTAACTTTTCCTCTTTGAAATAAATTCCCATTTGGAACATCA GCATACAGTTTGAACATTTATTCGCCTCCTGAGCTTGTACAACAGTCGTGGGAGTTGCTG CAGAAGCAAGCGAAAAGCCAGATGAGCGCTTCTAAACTTAGAGAGAGGTGAGTAAGGCTT GTGGGCGATCACTTGTCGGCTGGGGCCTCTGGAAAGCAAGAGGTTGAGTAAGAATGCTGG GTGCACCGTCCTGCTAGTGCTTTTCTTCCACGGTGGTGAGATTGGAGGTGGGATGTAATG GTGGGGGTTGTGGGGAAGCACTGGCCTTGGAGTCAGAGGGCGGCACTCAAGTGTGGACTG TTGTGCCCTGGGCAAGTCACCTCAAAGCTCTGAGTCTTGGTTTCCTCGTTTGCACAGCGG GGTGAATGCTACCCCTGCTGTTCCCCAGGGGTGACGGGTCACCGCCTTGGTGAGGACAGT GCTTTGCAGATGTGCAGGTGTTTCTGCCACCTCAATCAGTTGGGCGGTTTCTTTTTTTTC TTTTACAAGGTGAGGGGATTCAAAGCAAACCCTTTGCTTAACTCAGGAAGCTCTAATATT TGAAGGAACTGCTTAACAGGCTGCAGAACCTGTTCTGAGTGCTATTTTGGCACCAATTCC TTTTTGTTTGTGGAGTAAAGTTACGCAGTGAAGACGGTGTAACACCAAATAATTGTAGAC TCTCACAATAGGTAAAATAGCTCCATTTTACAGTTAAGGAAGCTGAGGTTCAACTGAGGC CCCAAAGCTAGTTAATGTACTAGTTCTTAGAACATTCTTTGAACACAAAGACTATGATGA ACTCCCTTCTGAGCCACTCACAAATACTAGCCAACCACTATCCTGCAGATCTTTGGGAAA GGGAAATTAGAAGTTCTTTTGGAGAGGCAGAGGTTGGGGAAAACTCATCACCCACAGAGT GAACTCCCATGTGGGGCTGCAAGGAAACCGAGCAAACCCAGTCCAGGCAGGACTCACCTT TGGCCTCTTCCCAGAGGATGTCCTGAAGAAACTTCCCCAGGGCCTGGCTGTGCTGCTGGT ACTGAACCCCTGACAGCTTGATTCCAACATCAAAGGGGGCGTTGAACTAGGAGGCAGGGC AGGGAGGACCCAGGAGATGTCAGAGGTCATGCCCATCCCCATCTCAAAGGGGGCTCTGGG CTCTCTGCCTCTCTTCAGGAGTGGAGAGGGAGAATGGCCTTTGGGCCCCAGCAGGGACTG CTGAGTGACACCTCAGCCAGGTTCTCTTCCTTTCTCAGGACCACAGCTCACCTTCCCACT CACCATCTTTCAGACACTTACCTTGCACTCTCATGCCTCTCAGCCTTAGCCTCTAATGGG ATTGCTGATAAAAGCTGTGGTGCCCCCTAGTGTGAGATTTTTTTTCTCCCTTGCAGTTTT GAAGACAAAAGGTTGAGTCACCAATGGCAGCATTTCAGGCCCTGGCAGGGGGTCTGCCCA GCATTCTCAGCACTGGCCTGCTGGCCTTCTATTCCTTCCCTGCTCCCAGCTCTTTCTCCT TTCTCTCTTGTCTGTTTCTTCTCCTTTTTCTCCTTCCCTAGGTATTTTTTCTCTCATATG CATAGACCTTTCTTTGATGCCTGGAAAATCAAAAGGAAGTTGATGTTTTCCTAGAAAGAG GCTCTGAGCCAAGTCCTTTCTGTGCTTCCATTTCTTCCCCTCTACAGGGAGAGCGCCTCA TCTCTTCCATTTTCCAGGTATTCCTGAGATGATTTATTGGAGCTCAAAGCTTTGGGTAAG TGGGAAGGAGCTCTGCTGCAGCCACATGGCAGACTTTCCTTGAGAGCAGAGATTGTCTCT GCCAGTGGCTACCTCGGTGCCTGGCCATATTGGGCACTGACTTATCTGAGTCAGGGAAGG ATCTTAGTGCTGGGTCATTTGGTCCTCACAGTAGAAGCCCAAGGAGTTGGAGGCCAAGGA CTAGAATGCAGGACTTTTAAACCCACTTGGCCCTGAAAACTGCTTTAGTCCTATTGCCCT TCCTCTGTGTGAGGCCAGGCGTCCTCAGTGCCTCCCTGTGGGGTAGGCGCTACCACTGTG CCCATTTTACAGGTGAGGACAGAGGCGCAGAGAAGCTATTAACCAATAGCTATGCGTTCC CTTTTCGAAATCTCCCTCCCCTTAACTCCACCATGAAGGTGGACCCAGTGGGGAATGACA TGATTGAATTTTTTTTTTTTTTTTTTTTTTTTTTTAAGGAGAGTTGGGGCCTTCCATTCC CTCCAGTAAATACTTGTTTTTCTTCCACCGCTGAGGCAAATGCGGGGTGGCTGATCACCT GGCAGACATCTTAGGAAACAGGAGCACCGGTCTGGGAAACTGCTGGCCTGGCCTAACACC TGGCGCTGTGGTGCAGGCAAGTGAGTGGTGACACAGTGCTGGCTGGTGGGGGGCAGCTTC CCTCCTGGCCTCAGTGGCCCATCTGTTCAATGGGAGTGGGACTTGGTCTCCAAAGTCTTC TACTCTGAAACTTGATTTTGGGAGGGAAACGTTTGGGGGGAGGTAGAGGGGCCTGAGATG AGAGAGGTGGGTGGGACACTCGGTTGTGAGGGGTTTGGTAGTGGGGCGCTCCAGGTCTCT GCAGCCACTCCTCTTCTGGCAGCCCCAACACCCCCCAGGCGTTTGACTTCTGGTTCCAGC CAAGGCAGTGTGGGTCACATGCTCCAAGGCTAGCTTTCACAGAAACTGCAAAGTTCCCGC TGTACCAGCCCCACCTTGCGTCGTCAGCCACCAAGACCTCTTTCTCATCTGGGTACTGGG CAGCTCCTCTGGCTGGGATGACCATGTGTGGAGCTAGCCGTCTCACCAGCAAAATATCCT GGTTTTGGCCTAAGGGTATGCAGCTCTTTCAGATGAGAATCTAGTGGATCCCACCGTGTA GAGGAAAGGTCTGAACACCGCCAGGTGCTGGTGAGGATGAAAGCGAGCAGGGGCTGGGGG AGCTTCCGACGGCTTTATTCCTCGACTGGAGAAGAGTATGGTAAACAGGCAGGCAGAGGC CAAGGCGGGCACATTTCACTCCTCTGGAAGGAAGAGGCCTCCCCTGGGCCACTGTGCGCT GTCTCTGTCCATCAGACCAGTGAGGAGGAAGAGGGCTTGGGGACTGGAGTCAGCCCTGAC CTTGTGTCGCGTCCCTTCCACACACCGCTGTGGTACCTTGGGCAAGTGAGTTCACCTCTG AACTGTTCCTTGGCTCTAAAGTGGGAGTAATGCCAGCCCTGCTTACCTCACAGGTTGTCG TAGGGAGGAGGTGGGGCAGTTAGAGGTGAAGTTGGTATCCTCGGGCACAGCGTCTAATAG CTGCCATTATTAAGTGCTACCTTGGGGGAATCCTGCCTTAGCTGCGAAATGGTGTCACCA ACCAAATATTTAGAAGAAACCATTCCCTGAACCACAGCCACAGGAAGGTTGCATAGAAAA CCCCGTAAAATCCTTTACTCCCTCCTCCTCTCCATCCTTGGGTTGTCTTAACTTTCTCCT TGCCCCACGCACGATTTGTCAGAGCACATCACCCACACCTGCCCCCTCCTTGCCTCCAGG CGAGGTGAGTGGGTGCCGGAGCCTGGGCTGGCGCCAGCCCTCCCATCCAGGGTGCTGTTC GGAAGCACTCCACCCCACAGTCCAGGCCCTGGAAGCCCCTGAGTAAAACATGGTTTTCTG CAGAGCAACATCTTCAGTCTGGGCCTGCCGTTTATTTCTGGGTGTCTTTGTCTCTGGGCA CTGTATTTTCTGTCCCCTTTGAGTCGCCTGGAGGCTCTGGCACCCTCTCTCCTCTGCCCA GGCTCCTTCCGTCCCTATTCTGTTGTAGCAAAGTTACTTCTTCTAGATATTTTTCTCTTA ATGGGTAAAGACCTCACAGAGCCCAGGGCAGAGCTCAACTCCTGTGGTACTGGTTTTATA GTTCTGGGGAGCTTGTAGTTGGGACCCTGTTCACTGCCACCTCTCCCTGCCCTCCCTCTC CCCTGACCCCACCCTCCTCGCTGCCACAGAAGCATAAAACTGCAGAGGTACCGACCCGGA CTTCCAGTTCATCCTCTGCCCCTTCTGCTTGACCTCCATCTTCCGGGCGGAGCCAGCCTG CTAGAGCTCGGGGCTGCAGCTTGGCTGGTGGCTTCTTCGACTCCTTTCTCTGCTGGAAGG GGGAAACAGTCTGTTTAGGACTCTAAGCCCCCATGTCCTTCCAGAAACAGTGAGGTCAGA CCCAGAGTCCTTTGTGCTCTGGGAGAAGACTGAAGCCCAGAGATGGCGCTGCTGCTCCAG GTCACAGAGCTGGTTGCTAAGTGGCAGGGCTGGAACAACATGTGGGGCTTTGTGGGGAGG TCTCACCTGGACTCTCTGGTGTTCAGGGCTCAGGAAGCTGGAGCCTGCCATGGCCAAGTC CAGCCAGAGCATGCCGAGGAGCAGGAGGCTGCAGACGGTCCCTGGGGAGGGCATGGCCTC AGCTGGGTTGCAGACAGGTGGGCCTGGGGGAGAGAGGGTCTCCAGGCAGCTGCCTCCCCT TCTCATGTGCCTCTGAGCTTGCTCAGGTAGGAGCCCAGCAGATGGCGTGAAGGGCTTTAC CATCTGGGGTCCTGACTGCTGTGTAGAGAGGACCCCCGCTTCCACCTCCCAAGGTAGAAG ATGATGGATGTGTGTTCTCTTCTCCAAGGCCGTTCAGGGCAGAACACCTGGCAGCAGGAC TTGATAGGGGCTGGGGGTCCTCCCCGGTGCCTTTTGTCCCAGGCTCTGAGAGCTCATGGC GAGTCTTTTCATGAGGAGGGAGGAAGCTGAACCAGCAAGGGCCCCAGGGCACTCAGCAGG GAGGGGGTTAGAGGTAGCTCCTAAATGAAGCTCTGTCTTCCAGCCAGACAGTCCGACATC CCCCGTGTTTAGAGGGGACTCCTGAGGCCCAGAGAGGTTAAACGGACGGGCAGCAGTCAC GGACAATAAACCTGTCAGCAAACGCACACGGAGAGTAGAGAGAGCTTACCTGCAGTTCCT GGCGGAGGTGGTGCCTGGTGGCTGTCAGGTCCTTATATAGGATGACTGGCGTTTGTTCTA AACCAGCAACCCCATCCCAGAGGTGGCCTAGCTTCCGTGGGGCTGATGTACATTCCTTGG GAACTAAAAATGTTCTTGTCCTCTGGGTAGAAGTCAACAGTGGAGGTCAGATGCCCTGCG GAATTGCTGGGTTGGCGAGGGAAGAAGCATGTGCTCCAGCTGTCCCTGGAACACGGTGGC GGGGTGCCCCAAGTGGGCATGGCCCTGGTGGAGGAGGGAGGGAGGAGAGTGGCTCTGGGG TCTGGGTGCAGCTTTGTTGCTGTGTGACCTTAGCTTACTCGCCCTTTCTCCCTGGGTAAA ATGAGGCTGTCATCACTAGGAGAGCTCTGAGACCTCCCCAGTCCAGCGCCCCGTTGTTTC CCATGTGCTGTTGCTGCTCTGGCCTCTGTGAGCCCCGGGAGTCCGCAGGGAGCCAGGCTG GTGATTCTACACCTTCCCGAGGAGGAGTCCCACCTCCCGGTTGAGCAGACTGCTCCTGAT CATCCTCTCCAGAGAGTGGGTGTGGGGATAACTTCAGCCAGTGGCTATGCTTCAGTCATT TCTGCCAGGTGTGACATGACTGCCTGGCCTGGCGTTTTTTCACATAGCAGCTTGCCTTGC CTCCCTCCAGCAGCTTTGGTCCCTATTTTAGCGGATGCCTCTTCTGAGAGGGAAGTGCAT TGGACCTGGAGGTGGAAGATCTACGCTTAGCACGGGCCTGGCTCCTCTCTCATTGACTGG CCTTACGCCGACCACAAATAATTCCCCTTACCCAGAGTCTTTGAGGGTGAAATGAGGCGA TGGGGGGAAAGTGGCTTCTAACCTGTGAAACACCCTGCAGATGACAATGGTTTCATACCA GGCCCATAGGACTTCCCAGCATAGGCCAAGGCCACTGCCTCATTTCCCTCGGCCCCAGGA ATTTCTTCCTTTCTGGAGTGCTTCATCCAACTGGGTGCCCAGGCAGGAACCCCTAAGGGC CAATGAGTTGTCTGCAGAGAAGTTCTAGCAGTTCAGGAGAGGAGCTCACCTTAGGCTGGG GCTTGCGGCAGGGATGTTAGCAAAGGCTCCAGGAAAGAGGCCTGTGGTGAACTCGGGGCA GGGCTTTGGAGGGAGGGCTTTGCGGCAAGCAGAGGGGAGGTGAAGGCGTGGGTAGAGTAC ATCAGGGCAGCATGGAGAAGGCTGGGTGGCTTGGGGGAGGGTGGCGATGGGGTCATAACA AAAACATAAGAAGGTGGTTTGGGGCCAGGTGATGGATGCCTTGGGAACTGCTAGCCCAAG AAGTTTGGGCTTTTTTTGCAGGAGGGCAGCCACTGAGGATTCTTGAGGAGAGAGAGACCA TAGAATGAATGAAAGAGTTGGAAAGACTTTAAAGCTCTGGGAGGCTGAATCCTTTATTTC GCTGGAAGAAAAACTGAATGCCAAGAGGGCCTCACTTTCCCCAAAGCTATACAGCCATCA GGGGCAATGCTGGGATTCCCCCATGGATCTCTTGACTCCTAATACAGTGCTCTTTCTGAT ATGCCATCTGGCTCCATAATGAACATTGTGTTCCAGGAAAATCAGTCTGCGCTGAACAGG ATGGAATTGGGGCAGGACGTCCAGTGAGGAGGACATTGAGGCAGTAGAGCAGTTGATTGC CGAATGACCACCTACCCTGACTTAAAAGATCAACCTCAGGGAGGATTGGAGCTTTCTAGA GTCTCTTGGGACAGCAGAAGCACAGGCCGGGTTGGACTGAATCTTTAAGTGGACATGAGG GACAAAGTACCTCCTGTTGGTAAACATCTCACCACCAACCCACTGTGGTGGCTAAAATCC CACCTTTAGTCCCAGCAACATATGAGCATGTCACCAGGAGGTCTTCACAGGCCTGTCTGC CACCTGAGTGTAGACATCTTTTGGCCCTGGAGCCCAGAGAGGCTGAATGTGGAGAGGGTG GAGAGAGGTCTGTAGTCCTCAGAGAAGACTTGCAGCTTTTTCAGAGCCACCAACCCATAA AAAAAAAAATCCCCAAACAGAAAAATCCTAACTGTGGTGACCAGGTACCTCCTGAGACAT GAAGCCTCCACTTACCTGGACCCTGGAGGCCTCTCCGGGCACAGCTGCCAATGTTGATCT TAGATAAGACCACCAGCAAGTAAACATCCACTGTGCAAAGCTGTGTTATCTTTGGGGAAC TGAAATGTCCCCTGGGAGTTGGAAACTCCCCTAGCCACATACCACAGAGTTGAGGAAGGA AGAGCTGATGGACGGAAGAACCATGGCGGGAGGAGTCATCCGGAAGCTACCTCGCTGCCC TGTCAGTTACGGAACAGAGGAGAGATGCCGGCTGGAGGACACAGCAAATTTGAACCAAGA GGAGCTTGGAGGAAGCCCGAGCGACCTGGAGGGGACTGGCTGACCTTCCTCATTCTTTTC AAGTGTGAATAATAACCAAGCCCAGTTTGGCAACTCCTTGAGGGTGAGGACGAAGCCCCA TTCTCCTTTTTGGAACTTGGTGGGGCTCAGGAAGCAGGTTCTCTCCAGTCGGTGGCTTTC CTTTCTGTTGCGGGTCTCTTGAGGGCCTGCCTTCATGAAGGCACATGAGTGACTCATCAT TTGTGAATTAATTGCTATATGTGAAGGGCATCTGAGAACAAATTATCTTCATAGACTTTT CATTATAATTTTATTTGTACTGATAATTAGTTGGTTTAGCAAGCTCTTTTTTCATAGATT TGGCTAAACTTCAGTCTGAAAGAGGCAAATTCTGGGGTTCTAGAAAGAGATTTTATTCTT TGATATAGGGCTATTTGGTGGGGTTGCTTTTTGTCCTAGTTGTAGCTTTTATAATTTCGA GATTCACATTTTGCAATAGAAATATACAGGCATACCTTGGAGGCATTACAGCTTTGGTCC CAGACCACAATGAAGCAAGTCACACGAATTTTGTTGGTTTCCCAGTAAATATAAAACGTA TGCTGATACCATACTATAGTCTAAGTGTGCAACAGCATATGTCTAAATGAATATACATAT ATATTTTTTTGAGACAGGTTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACTATCA TGGCTCACTGCAGCCTCCACCTCCCTGGACTAAGATGATCCTCCCACCTCAGGCTCCCAA GTAGCTGGGACTACAGGTCACACCACCACACCCAGTTAATTTTTGTATTTTTTGTAGAGA CAGAGTCTTGACATGTTGCCTAGGCTGGTCTTGAACTCCTGGCTTAAGTGATCTGCCTGA CTTTGCCTCCCAAAGTGCTGGGATTACAGATGTGTAGTCTTTGAAATCCAGTGTGTGTTC TTACAGTGCATTTCAATTTGGACTAGCCATGTTTCAAATGCTCAGCAGCCACATGCGGCT CATTCTAGATAGGCGGCCATCGCTCTTAAATCCTCCCTGACCTTAGCCATGCTCTCTCAT CCCTCCTCTTCGCCAAGCTCTGCCTCTCTCACTGGGGCTTCCCTAGCCTCCGGCCATCTT GGGGCCAAAGCTCTAACACTTTGCCTCTCTCGTGTCTTCTGTTCCCCTCCAGTGGCTTCT GCTTTCTGCCTTAAAATACACCCAGGTTCCTAATCCTGAAAACGTCTGTTGTGCACCGAT CCCACCCTCCCCTCGTGTTACCATCTCCATTTCCTTCCCCTTTCCTTGTGTCCTCTTCTT TGCTGTGTCCTGGCCCCTCAAAACTTGACCTTGCCTCTCATCCCCACTGCTGTACTGAAA CTGTTGTCTCAGCGTTGCTGATCATCCAGCCTTTTAGTCTATGGACCGCTAAGAGCCATA GGACGACCTCAGGGTGGGACGTGGCTTGGAGGGCCATCTCGTCTCAATTTCCAGATACAG ACCTGTGTTGGGTTGTGTTGGATTCATGAGGAAAGCTTCATAAGTTTTATGCACGTTTAT AAGACTCCATCCTTGGATTCTGATCCAGTAGCTCTGGCGTGGGGGCTTTAGAATCTGTTT CAAGTATCTCAGGTAATTTTGATTATAAATTACCAAGTATCCCAGGTAAATTTTGATTAT AAATGCTTGCTTCCAGCAGAAAATATAAACATATGGAAGATGAAATCTTTCTCTCTGAAT AACCCAATTCAGTTTCCACTCGTGAATATCTTATATAACCGTAGTACATTTATCAAAATT AAAACACCAGTGTTAGCACATTACTGTTAATCTCCAGACTATTTGTAAGTCACCAATTTT TCCATTGTCCCATCTGTTCTTCCTTTTCTTTCTCTTGTCATAACCACTTTTAGAGGGTTT TGAATGGTATCATTTTGTCTTCACCGTCGGCTTATTAGCTATACTGTACTGTTCTATTCT TTGAGTGGTTGCTCTAGGATTTACAAATATGACTTCAACATATTGCAGAATACCTTCAAC AACTACGATATCCTTTCACAGATAGTGTAAGAACTGCACCACAGAATGCTTTCATTTCCC CACTTCTATTCTTTGTGATATTATTGTCACACATTTTATTTTTACTTAAGGTATGAGCCC CACAATGCATGTTAAATAGCCAAAGTTTTTAGACAGATTAAAGAAATTAAGAAAAAGTCT TATGAACTCAGGTATTTACTATCGTGTTGCTCCTTATTCCTTAGTGCAGATCCATTTTTC TTTTCTTTTTTATTTGAGACAGGGTCTCACTGTGTCACCTGTGGTTGAATGCAATGGCGT GATCTCAACTCACTGCAGCCTCCACCTTCTGGGCTCAACTGATCCTCCCACCTCAGCCTG TAAAGGGATATTTGCAAAGGGATATCGGAGTTGTTGAAGGTATTTGCAATATGTTGAAGT CATATTTGTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGTC CAGGTTAGAGTGCAGTGGCGTGATCTTGGCTCACTGCAACCCATACCTCCTGGGTTCAAG CAATTCTCCTGCCTCAGCCTCCTGAATAGCTGGGACTACAGGCATGCGCCACCACACCCA GCTAATTTTTGTATTTTTGCTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTTGA ACTCCTGACCTCAAGTGATCCATCTGCCTTGGCCTCCCAAAGTGCTGGGATCACAGGCAT GAGCCACCGCGCTGGGCCTGAAGTCGTATTTGTAAATCCTAATTTTTGTATTTTTTTTTG TAGAGACAAGGTCTCACCATGTCGGTCAGGCTGGCCTCACACTCCTGGGCTTAAGCAATC CTGCTGCCTCAGCATCCCAAAGTGCTGGGATTACAGGTGTGAGCCGCTGTGCCCAGCCTG TTTTTCATCTAGTATTTTCCTTCTGCCTGAAGGAAACTTCTTTGACATTTCTTGTAATGG CAGCTCTGCTGGTGATTAATTCTTTCAGCTTTTATTTGAAAGAGTCTGTATTAAAATATA TATATATTTTCACTAGGTATAGAATTTGAGGCTGACAGGTTTTTTTTTTTTTAATTTTTT CAGTACTTTAAAGATGTTAATTTTCTTATGGTTTGCCTACTTTCTGATGAGAAGTTGGCT GCTGCTCCTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCGCCCAGGCTG GGGTGCAGTGGCGTGATTTCGGCTCACTGCAACCTCCACCTCCCGGGTTCAAGCAATTCT CCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCTACCACCATGTCTGGCTAATT TTAGTAGGGATGGGGTTTCACCATCTTGGTCAGGCTGATCTCGGACTTCTGACCTCGTGA TCCACCCGCCTCAGCCTTCCAAAGTGTTGGGATTATAGGCGTGAGCCACGGCGCCTGGCC TGCTGCCACTCTTATATTTGTTCTTCTGGATGGAATGTCTCTTTTTTTTCTGGTTGCTGG GAACATGGGCTATTCCCACCCCTATGTGAGCTCCAGCTGCTTGGTCTATTGGTTTCACCC TTCATATATGAAGGTTAGTACTTGTCCAAAGACTCCAGGAGACTCTTCAGCTCTCAGGAG CTTGCTCTGTGCAGCTTCCTCCTCTCGTCCTCTTCTGCCTTCAGTTCTGCCTTGGTCTTT TTTGTTTGTTTGTTTGTTTTTTGAGACAGAGCCTTGCTCTTTCGCCCAGGGCAGAGTGCA GTGGTGTAATCTTTGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCAATTCTCCTGCCT CAGCCTCCCGAGTAGTTGGGATTACAGGGGTGCAACACCACGCCCGGCTAATTTTTGTAT TTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCTTGATCTCAG GTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACCGCGCCC GGCCTGCCTTGGTCTTCCTGAACTCTGACTTCTGTCTCTTCAACTCCTGGAGACTACTAG ACTCTGGAGTCTCTCTTTACCTTTTGGCCCAGAAACTGCTTCTGGGTAGTAGTAACCTGG TGCATTTGTTGTGCTTACCTGTTTCCCTTTTCCCAAACACTGCCTGTTGTCCTATGTCTG AAAGCAGTAGTTGTTTCATGTACTTTTCATGATTTCCTAGTTGTTGTTTTTTTTTTAAAT TTATTATTTTATTTTATTTTATTTTTTTATTTTATTATTGTTATACTTTAAGTTTTAGGG TACATGCGCACAATATGTGGGTTAGTTACATATGTATACATGTGACATGCTGGTGTGCTG CACCCATTAACTCGTCATTTAGCATTAGGTATATCTCCTAATGCTATCCCTCCCCCGTCC CCTCCCCCCACAACAGTCCCCAGAGTGTGATGTTCCCCTTCCTGTGTCCATGTGTTCTCA TTGTTCAATTCCCATCTATGAGTGAGAATATGCGGTGTTTGGTTTTTTGTTCTTGCGATA GTTTACTGAGAATGATGATTTCCAATTTCATCCATGTCCCTACAAAGGACATGAACTCAT CATTTTTTATGGCTGCATAGTATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAGT CTATCATTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCGCAG TAAACATACGTGTGCATGTGTCTTTATAGCAGCATGATTTATAGTCCTTTGGGTATATAC CCAGTAATGGGATGGCTGGGTCAAATGGTATTTCTAGTTCTAGATCCCTGAGGAATCGCC ACACTGACTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTC CTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGACTGCCATTC TAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTCTGATGGCCAGTG ATGATGAGCATTTTTTCATGTGTTTTTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGTC TGTTCATGTCCTTCGCCCACTTTTTGATGGGGTTGTTTTTTTCTTGTAAATTTGTTTGAG TTCTTTGTAGATTCTGGATATTAGCCCTTTGTCAGATGAGTAGGTTGTGAAAATTTTCTC CCATTTTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTT TAGTTTAATTAGATCCCATTTGTCAATTCTGGCTTTTGTTGCCATTGCTTTTGGTGTTTT AGACATGAAGTCCTTGCCCATGCCTATGTCCTGAATGGTAATGCCTAGGTTTTCTTCTAG GGTTTTTATGGTTTTAGGTCTAACGTTTAAGTCTTTAATCCATCTTGAATTAATTTCCTA GTTGTCTATAGTGTGAGGGAAATTCTTATTTATTATTAAAGAGACAGGCTCTTGCTGTGT TGCCCAGGCTGATCTCAAACTCCTGGGCTCAAGAGATCCTCCTCCCTCAACCTTCCAAAG TGCTGGCCACTGCGCCCAGCCAGGGAAATTTTTTTTTTTTTAGACAGAGTCTCACTCTCT TGCCCAGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCACCTCCTGGGCT CAAGCGATTCTTGTGCCTCAGCCTCCTGAGTAGCTGGCACTACAGAGGCACACACCACTG CACCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCAGGCTGGTCTTG AATTTCTGGGCTCAAACATTCCGCCCGTCTTGGCCTTTCGAAGTGTGGGATTACAGTTGT GAGCCACCATGTTGGCTGGGAAATTCTTACAATCGTTAATCCTTTATATGCAGAAGTGGA AGGTCTCCCCTTAGTGTTTCTGGGCTCACTTGTAAATGGAAGCCTGTGAATCTTCTAGTT TTGGGAGTTGTTTTCACAGTGGCTTGCTGAGTTTTGCACTCAGAATGGATGAGTATTTGA TGGCAATTTTTGGGGTCTCTGGCTTATAGCACCATAAAAACTCCCTTTTCTTCACCCTGC TGATCTCTCAGAGGTATTGTGTCTATGAAGGCTTTGGCCTGCTCCATGTTCTAGGGTCTG TGGGTTTCTTTTGCTGTCCCAGTTGCTTTGTTTTTGCAAAAGGATTAAAAACATATGGCT GCTAGCGCCATCTGGCCCTAACCAGAGCTCTATGCCTTTTAAATTTCCCTTACTTTTATC TCATTTGGGCTTGACAACTGCCCGGCAAGTTTTACAGATAGTATTTCTATTTGACTAGGC TATTTTGTGGTAATAAATTTTGGGGTCTCCTCTTACCCAGGAATGGTTAATGTGTTGCCA CTCTAAGTATAAACAACTATTATGGTGCCAACTTCATAATTATCTTAACCAATCCTTGGT GGTGGGAGTTAAAATAGAGCACACAGTCAGGGACCCATTAACCTACCACCAACCCAGAGT GACACGGGACTAGTTCCTTCTCGGTATTTTCTTGGCGACAGCAGCTGGCACCATAGGAAG CCCAGGCCCAGGCTTGAGGAGCACAGAGCGTATCAGGGAGGCAGACGTGGATATGGTTCA AGGATTCACTGTAGAACTCGACACTCAGTAGTGCACGTGAAGGTGCCTTCCTGGGCTTTG CTTTTCTGAGTAAGGGAAGGAAGGAAGCAGCTGTTTTCATGTTGGTCTCAGAAGGCTTGG GCTTTGTGGACTGACTGGAGGCTGACTGGGCCAGGCCATGGCCTCTCTGTCCTCACCTTT AACCAAAGCAGTTTCACTTTCTTCTATGTTACATAGTATGATCAAAGATTTTTTTTTTTT TTTAAAGGGGATTTTGCTGCTGAAAAAGGAGGGAAGGACAAGAAGTAGGCAGACTAGGGG GCCTGAGGCAAGTGGGCTGACCTTTTATCTGAATCTATTCATACAAAGGTTTGGTGTGAG AAACATCCTTGTATTACAGCTGAGGAGAGCCCCCCAGCTCCCACCCTGATTCTACAGTGG GGAGTAACTGTTGAGATGGGCCAGGCCCTGACGCTGGCTTTACGTTTGCACAGTCCTGGG CAGGGCTTCTACCTTCTGAGCGCTTCCTCATCAGTGAACTGGGTACACCCACACGGGGTT CTCGTGTTGCTTAAATTAGCGAATGTGTGAAAGATCCAGTGTAGGGTCTGGCTCACCGCA GGCTCACTGATGGCTATGGCGATTGTCAGGGTCACAGGGCCTCCGCTGAAAGGTGATACC TGGTTCAGGGTCAGTTAGGTCTCCCATCATGGGGCCCTCCTTTTCCTGACAGGGTCAATA AACTAAATGAATCGTGCCCACTTTCTGGGCCAGCATCTTAACTATTGGTGTTTGGTTAAT ACCACGTTGCACCTGCGTGGCATTTTGTAGGTCACCAGATGCACTAGCGTGTTTGAATCT TGCAGCCATCCTGTAGGGCAGACTGTATTAGTCCCATTCTGCAGAACAGGATGTGTACCG AGAGGGTAAGTAGCAGACCCAGGGCTACAGTCCTTGTCACCAAAGGCTGAGTCCAGTGCT CTGTATGGTGCTTTCAGTATAAACTGAATCAGAGATGCTCATGCAGTGACAAGCCACCTT TGTGCGTGGGGTTAAGCCAGGCCATCACAGCCGTGGCCTTTGTGAATAGTTTGTTCTAGT GCGTGGACCGACAAGAGTCAAACTGAGCTGGTGGGGTGGGGTGGTTAGGATAACGCAGCA GGAATTATAAGCAATATGACTTTATTTAGTTCCTTTGGAAACAAAACCCCCCAAATAATG CCTGAACCCAAAGGTACATAAAAATGACCCAAAATAGATTTGAACATCACTTGTAGTTTC TTCCTCGTAACATGAGTGCTTTCAGCTGGACAGTAGATTACAAAGCATCTCCGATCACGT TAAGGCAGATGATCAATCTGTGGCTGCATCTGTAACTCCTCCTGGGAAAATAATCCTGTT GGAGTTGGGGGCTCTTCCCAGTTGTCTGGTTAGTTGGCCCAGGAAGGGGCAGTCCTGGAG CTGGCGGGTGGGGAGCCAGGCCCCACCTGTCTTGTCACTGCTCGTTCTGCTGGCCCTCTG TCACTGATGCTGATACGGAGCCCTGGCCCTTGTTGACATCACTGATGCACACCCACTGCC CATCAACTGACTCCTTCCACAGGGTCACCTGCGAGTCAGTGCACAAGCAGATTATCACGG GTCTGTGCCCTTCCCTCTGCTGTCCCCTAAATATGAGCCTCATCCTCATCAAGAACCACT GCCCAGAGGCTTGTGGGTGAACAGAGCATGTCCCTCCTCCACTGAAATCTCACCAAAATG AGAGTCCAGGAATAAAAACTCACAGAAAAAAAGGAGTAACAATAACAGCAGCTGTGGATG ATGATGTCAACACAGGATACTGTTTTCAGCAAACTGTGACAGAGCTACAGCGAGAGGATA TGGGGTGGCGGGGAGCAGGGTTCGCAAAGTGTGGTCCCCAGACCAGAGCAGAGCATCGGT CACCTGGGAGCTTGCTACAACTGCAGATTCTTGGGGCCTGGAACAACTGATTAGGAAGCT CTGGGGGTGGGGCTGGCAATCTGTTTTAACAGGTTTAACAACACTGCAGTTTGAAAACTA CTGTGGTAGAGGAAGGTAACAGTTCAATATGTTGTTTCTACACTGAAGTAAACTGTATAA GAAATAGCTAAGAGCTGAAAAGGTTTGCCCCTGGAGAGAAAATTAGGAGGCTGCATTAAA AAAAATCAGTCTAGGTCGGGCATGGTGGCTCACGCCTGTAATCTCAGCACTTTGGGAGGC TGAGATGGGTGGATCACCTGAGGCCAGGAGTTCGCGACCAGCCTGAACTGGTGAAACCCC ATCTCATCTCTACTAAAAATACACACAAAAAAACTAGCAGCCACCTGTAATCTCCCAGCT ACTGGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCC GAGACTGCGCCACTGCACTCCAGCCTGGACGACAGAGCGAGACTCGATCTCAAAAAACAA AACAAAAAACAAAAACAATCTAAACCTATGTACATATATTAGTTTGATTAAAAATGAAAA TAACGATTTTGATTTTAAGAACTCTTGCTTTAGGGACAAACTATTCACTCAACACACTGC AGAATGCTCTGGGATTGAAAACATACTAAGTCCTTTAGGTAAGGGTGCTATGGAGACAGC GAAAGGAAACAGGCTTGTAAAGAAGAGCAAGAAGCCTAAATGCACAGTGACGGGCCCCAC AACACTGCGTGCACAGCCAGGCACTTGCTTACAGCCTTGTAAAAAAGTCACTGGGGGCCT GCTTGAGGCAATCTGGGTCCCTTGGTCTGCCCTGAGTGCCATCAACCTGGGTTCTGGTCC TGACTCTGGCACTCACTAGAAATATGGCTTTGAGAGGGGGCCTGCTAGATCTTTCTGGGA CCACTGTAGATGAAAGGGACCCTCGGCCAGAAAAGCCGCCTGCAGAGGCTCTCAAGATCT GCACACCCATGTTCACAGCCACACTATTCGCAATAGCTAAGAGGTGGCAGCAGCCCAGGT GCCCTTTGGTGGAGGAATAAGTGTAGAAACAGGGTGTGGGCTGTCTATACAATGCAACAC TACTTAGCTTTACAAAGGAAGGAATTCTGACACATGCTACGTACAGCATGGAGGAACCTT AAGGGCATACTGCTAGTGACATAGTCGCAAAAGGACAAATACTGTATGATTCCACTTAGA TAGGTCGCTAGAGCAGTCACATTCACATAGACAGAAAGGAGAAGGGTGGCTGCCAGGGCT GGGGAGGGGCAATGGGGAAGGGAGTTATTTAATGGGTACAGAGTTTCAATTTTGCAGCTG AAAAGAGTTCTGGAGACCAGCTGCTTCTCTGCCTTGCCTGTGTTGGTTGTGCCGTGAGCC ACACAAATGAAAGGTAAGACATGGAGCCAAAGTGGCCACTGGGAAACAGTAAAAGACCAA CATAGGCAAGGGAGAGAAGCAGCAAGGGCTGGCAGGATCCAGACCAACTCGCACTTCAGG CGCAGAGCAGATGTGCCTGAAAACGCAGCACAGCCACTCCACGTGGAACTGACCCTGCGG CGTTAGAGATCCTCTGTCTTATAGGGGAATTCAGCTGGGCAGATGGCTATGGCTTGTTAC TGCTTCCTTTCTGCGGGTAGCTTTTTTCCTTCTAATTGTAAAATACACGTCACATAAAAT GACCTTGGCCACTTTTAACTGCACAGTCCAGTTGTGTGAAGTACATTTGGGTCCCTGAGC AGCTGGTCTCCAGAACTCTTTCAGCTGCAAAATGCAAACTCTTCCAGTGCACCCACTGTG TACCTGCCTCTTACCAGCATAACAAGTATTCATAAACTCTAAAGGTTTTTAAAAAGCCTT TTCAGTGTTATGGACAAAAAATATCCCCAATCTTCTTCTGTTTATGGGTTCTTATACACT TGCCTTTTTGGCACAGCTAACTGAACATCACCATGAGGTGACCAAATGCTTAGTAGGGTG ATGGGCCTGACTGGCTCTGCCACCTCATAGTTTTGGGACCCCCATGCAAGTCAAATCGCC TCTGTCAGCTTCTTTCCTCATCTGTGAAAGGGGGACGTGTTAATACTACCTCAGGGGCTG TGACATTAATGATGTAACTAAGAGGCACACTCAAAACGCAGTCCTGGCTAAGGCTCCTGC CCAGCCTGCAGTCAGATGGGAATGTCAAGTGCCCTCTCTAGTGGGCGGGGTGAAGACCAA CAGGCTGTGTCCACCATGCCACGGGGAATGGGTATGTACCTTATTGTCTCCACCAGAGAC AGCCAGGATGTTGGCTGTGATGGACCAGCTCACATGCCACACCACATCGTTGAACTTGTG CAACAATTTAGGGGACCACGTATTGCTTGAGGCATCATCACAGGTCCAAATGAACACACG ACCATCCTAGGAAGAAACAGGATAGAGTCAGGAGGTGGAGTCAAGACTCCTGCGTTTGTG ATGTGATGTCCTCCCAGTCTAGAGCCACCCGGCACCTCTCTGCAGGAACAGGGTGGGGGA TTCAAAGGGGAGCCGAGGACCTCTGGGGCGTCCACAGCTTTGTTTCTGTCTCTTCACACT GGTTAAGAGTCTCCCGGATTCCTTTTCTCATCCGGGTTTCGGAGGTGGACTCTGTCTGCA TTGCTAACTCAGATTTTCTCTGGGGTTTTCCTCATGCCTGCCAAGTCACTTCCACTGGCC GTCTATACCTTCTCAACTGAATGGGCAGAGCTCTCCAAAAACCAAGCTCCAAGAATGAGA AGGCACAAGTAAAAAAGCACAAAAATCCCAAGTTTAGAACCAAACCAAACAGGTTCCCAT GATGTGAAAGGCCTAGCTGGCTCCCTCTAGGGTGGTGGTGTATAACTGAAGGCTCACCCT TGGCCGTCCTTGCTGTCTGGGAAGGGTGGCTTGGTAGCTAAGCGTATAATTCCCATCCAA CCCCATCGTTGCTTGGGAACACTTGGAACTGCACCTGGGCACCTCGGCGCCCTAGTCTCA CATGGGTCAGAAGGGAAAATTCATCCCGAATCCGCCTCCTTCTTGGTGCCGGTTCTGTTG TAGCTGTCTCATCTCAGTGGAGGCAGGCCACTTGTGGCTTCTGACCAAGACTTCCCCACA CAATGACCTGACTCCCTGTGCTCTGGGCCAAAGGTGCCTGTTGCTCTCCCTTTACCTTCC CAGAGGACTTTCTGCTAAGGAGACTAAGAGCTGATGGGCCTGACTCGAGACTAAATGACA AGGGATACTCATGGCCCTGGGCTGACCTGGGAGCAGCTGGCGATGGTGCTGGTGGGCAGG CCGATGGAGGGGGCCCAGGCCACATCTCGAACCCAGTCACTGTGCGCTTCTAGCTTCTGC TCCTCCTTCCACTGGCCGTCCTCCTCCTCCCTAACAGTGGGGACAGAAAGAGAATCAGCA GGGGGCCGTTCCCACACCTCAACTCCTCCCCAACCCAACAGGCTCTGCCTGGGGTGGAGA AGCGATTCCATCTTTCTTCTTTCATTCATGGAGTTTGTGGCATTTTATTCCCTTCACCCC AGCTGTAAAAAAAACCCTCCAGAAAATGCTCTGCTTCCACAGCCAAAGAGTCAGCTCCAA CAGTTGGGAATTAGGTGAACAGGTGTTGTGTTGTTTTTCAAGGATGTCCTCCAACAGATT GAAAACAGTATTTTACTGGCAGGAGGGAGAAAGAAAGGTGACCTTGTTTCTTGTGAGTGT GGCTGAGTCATGGTGAGTAGGGTAAAGGGTAGAAGTGTCCCCTCAAAGAGAAGGCCACAC ATCCCTACTTACTTCCACAGCTTGATGAGGTTGTCACAGCCACCTGATGCAAACCTCTTG ATGTAATTGGGTTTCTGCCCCGATGGGTGGTCTATGAGGCTTCCAGGTACAACAGCAGGG GCCCAGCTGACGGCATTGCAGCCAATCTGTAAAGATGGGACACATGGTGACTCTGCCTTG CAAGAGAACACTGCTTCTGCAGACCCAAGCCTGCTGTCCCTCTCCCCTCCGCTTCTCAGG ACTGGAGTGTGTGTGAAGGCTGACATGAAGCACTCATCATGGGGTCCACTGCTCAGAATT CTCCCTCAAGGATCCCAACAGTGTGTGCATTTTTCTGCAGTGTGCGCTAAAAGTAGAAAT TAAGAACTCCCACAAGTTTAAGAAACAGGACATTTTCTAAACACATGAAAGAATGGTACA TTGGAGCTTTTTTTTAAGAAAAATCTTTTATTATAAAGTAATAGATCAAGAAACAAGAAT TCTGCCACCTGCCTGAAAAGCCCTGTCATTATGCCCTTCCTAATCACAGCTCCCTCTTCC ACTATAAGTAACCACTGCCCTAACTTCTAACCCATTTTCCCCCCATTTTATCACCCAAAT GTGCACCCCTAGATACTATAGTTTAGTCTTGTCCATTAAACATTTTTTTGGATGTTTTTT ACATCTCCTACTTTGCAGATTCCTCCTCTGATTTTTTTCCTTACAATTTTTCTGCTGAAG AGAGCCTAGTCTCTCGGTCTGGGTTTTGCTGCTTCATATGCAGTTCAATATGTTCCTCTG AATTCCTGAAAACTGTCAGCTGGAGCCAAGACTGGACAGACTCAGGTGTGATCCCTTTGG CAAGACTAGAGCTGGTGCGTTCTCTCATCAGGAGGCACGTTAGATTGTCTCTTATATTAA CAGCTGTCAATAACTCAGGCCTCTCTTAATTCACTGGGGCTTGTAAAATGGTGATACTCT AATTCCATCCTTTCTTTGTCATTTATTCCATGGAATGCTCCAGATAGGGACACTTCTTCT CATTAACTATTCAGTTACCCAGGGATAGAGGTCTGATATGGTTTGGCTGTGTCCCTACTC AAATCTCATCTTGAATTCCCACGTGTTGTGGGAGGGACCTGGTAGGAGGTAATTGTATCA CAGGGGCAAGTCTTTCCCATGCTGTTCTCATGATAGTGAATAAGTCTCGCTAGATCTGAC GATTTTAAAAATGGGAGTTTTTCTGCACAAGCTCTCTCTTTTGCCTGCTGCCATCCACGT AAGCTGTGACTTGTTCCTCCTTGCCTTCTGCCATGACTGTGAGGTTTCCCCAGCTACGTG GAACTGTGAGTTCTCCATCCTCTTTCCTTTGTAAATTGCTCAGTCTTGGGTATGTCTTTG CCAGCAGCGAGAAAACAGACTAATACAAGGTCAAAAAGGAAAGGCTGGATAAACGCTTGA TTCTTTCTGAACTGGTTCTATCACTTTCCAAAGATGACTGATTCTCCTCTTTATTTATTA TTAACAATTTTTTTTTTTAAAAATTGAGACAGGGTCTCACTGTCACCCAGGCTAGAGTGC AGGCTGGTAAGATCATGGTTCACTGCAGCCTCAAACTTCGTAGGCTCAAGTGATCCTCCC ACCTCAGACTCCCAAAGTACTGGGATTATAGGTGTGAGCCACTGCCTTTTTTTTTTTTTT GAGACAGAGTCTGGCTCTGTTGCCCAGGATGGAGTGCAGAGGCGCGATTTTGACTCACTG CAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGTGTAGCTGGGAC TGCAGGTGTGTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGCGTCGGGGTGTGT TAGTCCATTTTCACGCTGCTGATAAAGACATACCTGAGACTGGGCAGTTTACAAAAAAAA GAGAGGTTTAATGGACTTACAGCTCCATGTAGCTGGGGAGGCCTCACAATCATGGCAGAA GGCAAGGGAGGAGCAAGTGACATCTCACATGGATGGCAGCAAAAAGGGAGAGAGAGCCTG TGCAGGTGAACTCCCCTTCATAAAACCATCAGATCTTGTGAGACTTATTCACTATCAAGA GAACAGCATGGAAAAGACCTCCTCCCATGACTCAACTCCCACTGGTTACCCCCTACAACA CATGGGCATTCAAAATGAGATTTGGGTGGGGACACAGCCAAACCACATCATGGGGCTTTG CCATGTTGGCCAGGCTGGTCTTGAACTCCTGAGCTCAGGTGATCCGCCTGCCTCAGCCTC CCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCTGCCCTGGGCCCAGCCTTTTAAC CCTCATTTCGTCTTAGTTCTCTACAAGTAACTATATATTTATGCTGAAGTCTTTGTAGTC ATTTTAGTTGTGTGACTTGTATCCTCTAGTAGATTTCTCAGGAAGGGCTCCTAGAAACAA TAGTCCCTGAATTCTTGCATATTGATAATAGTTCATATCCTTTACACTCAAAAGCTAATT TTAAAAACAGCTTTGATATAGTATAATTGACATAAACTGCATATCAAGTGCATGATTTGG TGAATTTTGACAAAAATATATCCTGTAGGATCATCACATCACCTCAATCAAGATAAGGAA CATGCCCATCATTCCCAAAAGTTTCCTCGGATCCCCTGGTAATCCATCTCCCCATCCTGC AGCCCCCAATCGTGGTGACCATGGGCCTGCTCAGCTGCATTTCCTAGATATTACAGCAGT GGAATCACAGTGTGTCCTTTTTCTTCTTTTTTTCACTCAGCATAATTATTTTGAAATTTA TTCTTCATCTTATTTTGTTAAGTCATTTCTTTTTATTGCAGTCATTTCTTTTTATTGCTC GCAGTATTTCCAAAGTATGGATATATCACAACTTATCATTTACCTGTTGATGGACATGTG GACTATTTCCAGTTTTTGGCTATTAAAGCTGCTATAACCTTTTGTGTATAAGTCTTTGTG TGAACTTCAAAGTCAATTTTCCTGGTTATAAATCCTTGGCTCACACTTTCTTTCCTGGAG TATTTTAAACATGTTATTCTTTTTTCTTCTGCACCAATCCTTACTATTGAAGAGTCTGAC AATAATCTAATTGTCTTTCCCCTTTAAGTCACAAGGTTCCTTTTCTCTAGAACCCCCCAA AATTTTCTTTAAAGTCTAATAATTTTACTAGAATTATATCTTTTTGTTGGTGATGCTGAG TTGAATTTTTTTTTTTTTTTTTTTTTTTAGAGACGGGGTCTCACTATGTTGGCCAGGTTG GTCTTGAACTCCTGGCCTCAAACAGGAGTTCACCTCGATCTCCCAAAGTGCTAGGATTAC AGGCTGAGCCATCACGCCTGGCCTTGATTTTTTTTTTTTTTTTTTTTTTTGAGACAAGTC TTGCTTTGTCGCCCAGGCTGGATTATAATGGCGTGATCTTGGCTCTCTGCAACCTCTGAC TCCCGGGTTCAAGCAATTCTCTTGCCTCAGCCTTCCGAGTAGCTGAGATTACAGGTGTGC GCCACCACGTCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCGCCATGTTGGTC AGGCTGGTCTTAAACTCCTGACTTCAGGTGATCCGCCCACCTCAGCATCCCAAAGTGCTG GGATTACAGGCTGAGCCACTGCGCCCGGCTGATATTGTTAAGTGTGGGGTATGATCTCTC AATCTCAAGTTTCAAATCTTTGTTTTTTAATTTTAAGAAAGTTTTCTGGATTACTTTTTG GTATTCTGTTTTCCTTTCCAGGGACTCCTGGTATTCGTATGTCTGACCTTTCTGCCTGTC TTTACTTTTGGTCAAAACCTTTTTACCTCTTCATTTTTTTGCTCTTGAAATGTTTCCTTT TTCACACTGTTTATCCTTTTCAGGCAGGATCTGCTGTGTTCATCGACACTTGCATTTCGT CTTAGTCTTTCTTTACTTCTGAAATGATTTTTAATTCTAATTCTTTCCTGAGTTCTGTCA CCTTATTTCTGATTTTTAAAAAGTTGATTTACACTATTCTCTCTTGTTTTGTATTGTTAG AATGTCACCTGGCTTGATTTGAAATAGCAGGTTACAGCTTGGCTCGGTTATGTGGGCATG TCTTTCTAATGTGCTCTCATTGTCCGCAGGGAGGTTATTTTGCATATTCTTGTTTCTTAT ATAACAACTGTATGCAATTTCACTTCAAATACTTTTCTGTTATTTTTAGGTGAGATGAGT TTTCCTGATAAGAAAGGCTCAGGAAAGTCTAAGCTCAGAACTCTCCCTTGTTTCTGTGTG GTGTTAAAAAACGTGGGAGATGGCTTTCAGGAGTTCCTGTCTTTGTTCCTCTTCCCCACA TTGGTCTACATCTCATCCTTCCTTTCCTGTGTCCCTATCCAGCTCAACTGTGATTTCATT TCCTGCAGTTCTTCCTCCTGAGGGGCCCTGTCCCAGAGGCTTGCTCTGGAGGATCACAGA GCTCAGATTTCTTCCCGCCCCTTCAGCCTTTCTTATTGTGGGCCGCTTCCACTCACTCGG TGTTACAGAGTGCAAACCCCTCCTGGTCATTTCTCCAAAGGCCCCCAGAAGATGCTCACC ATCATCTTTGATTAGCAAAATGCAAATAAAAATCACAATAAGGGCCGGGTGTGGTGGCTT ACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGGATCACTTGAGGCCAGGAGT TTGAGACCAACCTGGGCAAAATGGTGAAACCCTGTCTCTACTACAAATACAAAAATTAGC CGGGTGTTGTGGCGTGTGCCTGTAATTCCAGCTGCTCAAGAGGCTGAGGCATGAGAATTG CTTGAACCTGGGAGGCGGGGGTTGCAGTGAGCCGAGATCATGTCACTGCACTCCAGCCTG GGTGACAGAGCAAGCCTCCGTCTCAAAAAAACAGAACAAAACAAACCCAAAAAATCACAA TAAGATACCACCTCACATTCACTAGGACAGCTGTAACCAAAATGACAGACATATGTTAGT GAGGATGTGGAGAAATTAGAACCCTCATACACTGCTGATGGGAATGTAAAAGGGTACAGT TACTTTGCAAAACAGTTTAGCAATTCCTCAAAAAGTTAAACACAGAATTACCATATGACT CAGCAATTTCACACCTAGGTATAGACCCAAGAGAATTAAAAACATATGTTCATGCAAAAA CTTATCTGCAAATGTTCATAGCAGCATTATTCATAAGGCCGAGAACATCCATCATCTGAT GAATGGATAAACAAAATGTCTATATTCACAATGGAGTATTATCCAGCCATAAAAAGGAAT GGAGTGCTGATACACGCTATGATATGGATGAAACTTGAACTCATTATAGTAAGTAGGAGA AGCCAGTCACAAAAGACCACAGATTGTCTCATTCTATGTACAACTGATCCTCAATTTCAT TTCATTATAATGCTGACAAGATTAAAAAAAAAAAAACAACTCCCAGCGGGGGCCCCTGCC TGTGTGGAGTCTGTGTGTTCTCCCTGTGTCTGCGTGGGCTCTCTCCTGGTACTCTGGTTT CCTTTCACACAATAAAGATGTGCATGTTCACTTCAATGGTACGTCTGCATTGTCCCAGTG TGAGTGTGGGGGTGTGTGTGAGTGCTCCTCTGGTGGAATGGTATCCTGTCCAGGGCTGGC TTCTGCCTCATGCCCTAAGCTGCCAGGACAGGCTCCAACCACCTGTGACCCTGAACTGGA ATGAGTAGATTAGAAAAAGAATAGATACAAATTATTGTAGAATTAAACTCATAAAATATC CAATAATCATACAGATGCATGACAGCAAACGATGTGGCATTAGTCATATGAGCCCCCCAC ATTGGTTATTGTTGGTTTTTGAACTGTGTGGTGGTAGGAGGTAGGACATTGATGTTCGCT TTGCAAACATTTATTCCTTGATTGAACCACCAACATCACGACCACTGTCACTCGCTGATT CACCAAAAGTTGGGTAAAGAATGACCTTGTTTATATTAATCTTTCTTAAATGTATGCATA GCTCACATACTTTTTAAAAGTTTTAATAACACCACTCCATTCTACAGGGTCCCAATGACT ACTGCAGGGCATGTCACCTGGAGGCAACCATAGCTAAGGTGGCAGTGAGCAGGCTGCTGC TGCACCAGCCCTCCCCTGCTTGGGAGCACACAACAAGGAAGCAGTGCCAAGCCCTGCCTG GTCTGGCTTCAGGGCAGAGAGGCTCAAAGCTGCTCTAGAGCAATCATGTCTGGTCAGCTG ACCACTCCCCGGCCCACTGTCCAGCGGGGACCCTCCCGTGCCACCCTCTAGGGAGGCTGC AGCAGACACGGGGCAAGGCAGGCGCTCTCACTGCACGAAAGGCAGGGGATGGACTCACGG TGTGAGCGTTGTTGATCTTCTTTACTTCCCATTGGCCTTCCCCGGTGTAAGTCAGCAGGG AGATGGCCCCATCCGAGCTCCCACAGGCCAGGATCAGGCCGTAGTCATGGGGGGCCCAGC ACACCGAGTTCACTGCGGGAAGAGGGAGAGTGCAGTGAGCAAAGCAGGGAGACCGCGGCC CCAGGTCCCGCCTTCCACAGATTTACTGTTTTACTAAATGTCTACAACAAACAACTGTAG GAGTCACCGGGGGAAGCTGTAACTTGGTCAACTGAGGACACAAAAAAACCCCATCACCTA CTAATACCACGATTTCATAACCTACAGTCTATCTAACAAAAAAGTGGGTAGGAAAACAAT CTGAGAATGAAGGGTAGTCCTTGCAATGAATAATCCTGAAGAGAAACTCACCTGTCTTTT CTTATTTGCTTTGGACTGGCTTTAGGTCTTAGGGCCTTACTCAGCTGAGGACAGAGTAGC AGAAAAGCCAACCAAAGCTCAAGAGACAGACAAGAGGCACCACGAGGGGCAGGGAGCCAG GGCTCCAGCCGGGACAGAGTCCTTTTTTACCCAGTGGTCCCCTTGCCCGCTCTGCTGCCA AGCTCAGCATACCTGAGGAGTCGTGTCCCGCATGCTCGTGGCTCTTCTCCCAGGTGCCGT TTTCCTCTCTCCAGATAATGACTTTCCGGTCATAGGAGCACGATGCCAGGATGTTGCCGT ACATGGGGTGAGCCCAGGCCACTTGCCACACAGGACCCTCATGACTACAAAGGGAGAGAT AGGCCAGAGGAACCCACAGTGCCTCTGCAGGCACTACTTTGGACAGAACTAAATGGCTCC CTGAGACGATATATCAGGGCAGAATTGCTTAAGAACTTCAAAGGGAGAACTATACAATGC CATTGCAAAAGGGGTGCTCAGTGGACAGTGAGGAGCCTGAGGTCCTAAGAGGTTAAGCAA CCTAAGGTCACAGAGCCTTTGAGAGAGAGTTGAGCCTCTGGGTCAGCCTTCCTGTCCTGG CCAGGCAGGAGCCTCACTTGCCCAGACTGCAGCCAGCACTGTCTGTATGTGCTGTCTACA GCATAGTCATTAATTGGTCCAAGGTTTCCAGCCAGAAGTGTTCAGGAAATATTTGTAGAC TGAATTGCTATTCATCCTTCCCGACGGTCAGCTTCCTGAGGAGGCATTATTGGTTTCATT TTGATGTTTTCCACTACTCTTTTAATTTGTTCGAAAGGCATGTCTTTCCCTTCTCTTCTG ATCTTTATCCATTCACCTGATAACAGGTGCTATCTGAGCACATGCTCTGTGCCAGGCTTT GTACGGTGACCATTTCTCTGGCCCAGGGAAGGTTTTGCACCTTAGCACTCAAGAGGTAGA GTAGCATGGTAGAGTTAGTGGTTAGGAGACCAGACCCATTCTCCCATTCACTAGCTCTTG ACTTTAGGCAAGGATATCTTTGTCTCTTTACCTGAAAATGGAGACATCAATAAGAATTCT TTCATAAAGTTTGGAACAATGCTTGGTAGAAGGAAAGAAAAAAGCCACTCAATACCCATT AGCTATTAGTGCTGCTCCTGGTTTACTCCTTCACCGTGGGCTGCACACACTCAAGTCTCC TCCTCCCTCTGGCTGGGACAACAGGACATTCCCAGTCCCTACAAAGCTGCTGCTAATGAA ACTGAGTAGACTCAATCTTCCAACAACTAGCACAGTTTTTACTAAGGGGAAAAAAGAATG GGGTGGGAATTTTTTTTATCCCTCCAATATTTCACATCCTTTGAATGTAAGAAAAACAGC AGAAAGGACAGAGTCACAGCAAACATAACTGCCTTGGCCAACACGCTGCACTGCAGCAGC TCTCTGCCTGCCTGGGGGGCTCCTGCATAGAGAAGCTTGATTTGGCTCCTCAGTCACTTG ATCATTTGACACTCAGACAGAGGGGAGCTTCTAGGCCCATTTCCCCAAATGGACACTGAC TTAGTTTATGCTTTTTAATTCAGTGAACAAACACATGCTGAGCACCCACCTGTCATGGCT CTTAATCTTTTCTGTGCATTCTGGGGAAGGTTATGGACCCTCATCAGACTAATGTACAAA ACACACAGAACTAGGCTTATAAAGAAAATTCAATTATAAATTATACAGTAATCAACTTTT TTTTTTTGAGAAGGGTTTCACCCTGTCATCCAGGCTGCAGTGCAGTGGCACCATCGTGGC TCACTGCAGCCTCAAACTCCTAGGCTCAGGCCATCCTCCCACCTCAGCCTCCCAAAGTGT TAAGGATTACAGGCGTGAGCCACCTTGCCCAGCCTGTTATCAAAATATTATAAAGCAATT TATGAGATAGTGATGCATGTACTTCTTTGTTAACACTTCAAGCAACAAACCCTAGCGGCA GGTCTAATAACCACTGTAATTTCAAAGTTGTGATGAGCATAAGTGGTATTTTGAGGTAGC TAAGTAACCGTGATGTGTGATGACAATATCTGTGAATTCTACTGGTGACAAAGTGACAGG CACTACAAATACTACTGAAGTTTCTGGCCTACATCCATAATTGAAGGAAATGCTAAATAT CAGAGTCACTGAAAATGCATTTTTTTCCCCCTGTCCCAATTCATCAACCCCTGAACTCTA TTCACAGAACCCTTGGAGATCCACGGCACCCAGGCAAACCCACAAATACGTGAAAGGCAG TGAGCTGAGGGAAAGCAGTAGAGATGTGGCCATAAAAATGAGCCAGGACTTCCTCAAGAA TCTCAGTAGGGAGCAGGGCAGGTCAAACATTTGTAAATAATCACTGAACACGTGCCACGG GCATATAGGCAGAACAATGGGATTTATAAAATGATAGCATTCTTACATTATTCTTACGGT GATGCTTTTGTGACACTTTAGGTCATACTGGCTAAACTTGAACGAAATGGTACTGTTTAC CACTTTTAAAAGTAGCAGTAGCTGCCTGCACTAAAGACTTACTGTGTCCTGGGCCCTGTG TCAGGGCCTTGCATACACTAGCTGGATAGGAGGTAGCATTGGCCCAATTTTGAGGATGAG CAGATGAAGGCTCTGAGAGAGAAACTGAGTCACTTGCCCAAGGTCTTCTGGTGGGTACAC ATAAAGTGGCAGAGCTGAGATTCACACCTGTATCCACCTGTGCCCTTAACAGCATCATCC CTGGGGACGTCCGCTGAGGACAGCCAGGCTGGCTGGGATCCCAGCGTCCTCTCCGCTAAA TGTGCTTTGGGGTTGCTCTGAATCTGGGCTCCCATGCTTTGCTCCCACGCTTGAAGCAGG GCCTGAGAACCCACACCATTCCTGGAGCCCTTCCCTGGGCTCGCCAGCACTTACCCCCTG AGGTCGGCGATAAGGATCTGCCCTCCATTGCGCACATCAAAGATTTTGACGGACCTGTCT GATGAGCAGGTTGCCAGGCGGGTGCCATAGTAGTCCATCTGGGCGTCGTGCTGCAAAGGG AGGACAGCTCGGGAAGCCTGCAGGCTGGGTGGGTGGGTGGGTGGGGTGAGGGCTGTCACT ACACAGAGTCTAGTTTGGACCAGAATCTCCCTGAAATCAATCTGATCTCAAAGTATCATC ACCCTCAGGCAGGAAGCTAGCATGTGGACATTCTCACTTCACCTATGGGCAGTGTCTCTC TGAAATGGACAAAGCAAGCCATGCCCAGCTGGTGTCACAGACCCTTTACATACCTCAGGG AAGGGCTCTTCCATTCCTGTTCCGCAGGGTGGGTATGGGAGAAAAAAAGTTGGCCTAGCT GCCCTCTTCTTCCTCCATCCTCTCAGGCCCTATTCAGTTCTTAGGCTCTGTGGGCTAAAG GGGAATACCCCTGGGTTCAGCTCAGCCCTAGCACCTGATGCTAATGCATGGGAGCAGGCC AAAGGAGTGGGCCTCTGACTGCCTGGAGTCCCCAGTCAGGTCTTCTGTGATGCAGCTCTG GCCTGCACACAGGGTTCCATTCAGATATTTGGGCTCTTTCCAGCCCTGGCCCTGGATCCT TTGTGGACCTTTGTTTTGGGGCTTCTGCTCGACCTTTTCCCTAGTAGTGTGCCCAGAGCT TCCCAGACTTTCCACCCAAGGAACACAATGCCTTAAGTGTCGCTGCTCTCACCACTTGTG AACCGAATTCCTTGATGCTGACTGAGCATGCAGAACTAGGCCTGGCCCCTACCTGCAGAT CCTTGTCCGCAGGGTGATGGTCTCTGAGGCACCATGCCTCCTGCACCACTGAACACCCTG GTCCCTTCTGCTTGCTGGCCCTGCCTATTCCAATGGATGTCCCTTTCCCCAGCTGTCCCA CCCTGGGAGTTTCAGGACTATCAGCTGCACTCCCATGGCCACCAGGGGCAATTATGCCCA TTCAAAGGCACTCATTCTGTCTGGCTCAGATGGGAATTCTCACCTCCCTACGCAAGGAAC ACATCCTGATTTTTCTTTGGGAACTCCCTCCACTGTATCAGGCCTTGGTTTCTTGGAGGG CAGGCAGTAGAGGAGTGTTTCTGAAGCACTTCTCATGCTTCTCAGTGGAAGGAGGCAGGA CATAGTACCTTTCAGATCTAAATCCTATCTCCTTAGTTTACCTGCTGTGCAAACTTTGAA AACACTTCATCTCCTTGAGCTTCAGTTTCCTTATCTTTATTATTTACCAACATCCTATGG GCCTTAGTTCCCTTATCTTTAAATAAGGCTAAAGATAGCATCTGTCTCAACAGTTGTTAT GAAGGTTAAACAAGATATTGAATGAAAACTCACGCCTGTAATCCCAGCACTTTGGGAAGC TGAGGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACTAGCCTGACCAACATGGAGAAA ACTTGCCTCTACTAAAAATACAAAATTAGCTGGGAGTGGTGGCGCACGCCTGTAATCCCA GCTACTCGGGAGTCTGGGGCAGGAGAATTACTTGAACCCGGGAGGCGTAGGTTGCGGTGA GCTGAGATCACGCCACTGCATGCCAGCCTGGGCTACAAGAGCGAAACTCCATCTCAAAAA AAAAAAAAAAAAAAAAGAAAAGTACTTAGCATGGGGCCTGACACTCAGTGAGCATGCAAA TGTTTGTCATTACTACTTGGCCTCATCTAGTTCTCAAACCAAACTCATACGAGTAGGTAG CATATCCATTATTTTTCCCGTAAGTAAATTGAGGCTGGCTCAGAAAAGTTAAGATATTGG CTAGGGAGTCTCAGACTGGGTCTTCCTGCCCATGATTCCATGCTATCTCCAAGGAGGTGT GGTCTTACAGCTAGACCACTCATGACTGAATCCAGAGAACATATACAACTCTGGGACCAG ACAACCTCTCAGAAACCCAAAAGCAACTGTTGGTGGACAGGTTGTGAGGGCAAGAACCCT GACATGAAACACTGTCAGCCAGCTGTCCTGGGTCTTGCTCAAAGGCTGCTTGGCCCTGAA TGAAGCAGAGTCTGTGTTTTTCCTGCGGTAGACTTTAACCTCTGGACCTTCTCCTGCAGC CCTGTCCTCTTATACTGAGCCTTGTGTTTACCTCTCAGGAAATGCCCTGAGTGTGGACTT CTGGTTCAAAGGGCCTTGTCTGGCCTATTGTCTTGGTGGTTTGACTGGGCTCTGCCTGGG GCTTTCACTGTGGCTGCCCTCTGCCTTTGTATTGAGTCATCTTTCTACACTCTCTTCTTT TCACCCCCCTTTCCAGTGGGGCTAAGAAGTGACAGCAGGAGGAAGACAGGTGGGAAGACT ATTGTCAAGCCTCCGTACCCACTCAGCCTTCATCCGAGAGCAGGTTATTGTATTGGCTGG AAGACTGACAGCCTAGAACTACAAATTATTCCCAGGTTCCTCCCAGCAGAGAGTGATTAG ACTGCCACAGTCCTGACAACTCAGAGGGCACTGCTAGGGAGCCTGCCATACCCCGAGATT ACAGGCTGATAGGCAACCACTGCAAAGCCACCCTGGATCCATGAATGATCAACAGAAAGG GGTAATGAAAACCCCAAATTGCTTCCCTCCCACAAAAATGCCCATGTCCACACCCCTCCA GGGAGGGTGATATTAATACTTACAATCATGTCCTCATGGGAGGTATCCACAGTGTTAATT ACTGACACCTAGAACCAAAGATATCACTGGTAAATTAACTCATGGCAGTTAGAATACAAC CATCTCAAGTTCTTGACTGCATTTGTTTGTTCACTCACTCATTCATTCATTCATTCAGTA AGCATTCATTCTAAGTACCTTCTTTCTGCCAAGCACTGTGCTAGGAACTGGATATACAGA CACAAATAAGAGGAACTTTTTGCCCTTGAGAAGCTCGCGAATAATGCTAGTGTCGCAAGA TAAATTATTTAATGGTGGTTTGTGTGTCCTGTAGGAGCCTGAGGGGCTGGGGTGGTAGAC ACGAATTGAGCCCTAGATGATGGGTAGGAATTTGCAGGTGGCACAGGGGAAAATACCAGT CCAAGCAGCCAAGCAGAGGGAATACACGAGTAGAGACAAAGAGGTCTGAGAGAGCCTGAT GTGTGTGGGGAAACGGCAAGCAGTCCTGGCTACCCTTAAGGTTGAGGAGAGACCCCAAGG GAGCTACAGCTGGTGTTCCTTTCCTGGATGACAGAGCCTCTGATGTTCCAGGCAGTTTAT GCATAACGGGGTTATTACTTCAGACTGGGAGACTTGATTCGAGTGTTTCCTGAGGCTGCT CCCTGGTCCGTCACGTAGTGGGATCCAGAGTTGAACAGTTTGTAGGGCTGGAACATGGTG TCATGGTCATCTCCCTCCTATCTATTCTTTGAGGTCCAGCTCAAAAAGGGCCATCCATCA CCTTTCTTGAAGATTCTCAGACCCTCAAATGGCTGGACTCTCTTGCATATCTTCAGCAAG GAACACATACAACACTTTATGCTGTTTCTTCTCCCCACTAGAAGGTGAGCTCCTTGGAGC CATGGTCTGAGCCATCTGCAGTTTCAAATCCCCTCAAATCATCCAGCACAGTGCTTTGCA AATAGAAGGAACTCAGCGACTATTTGCTGAATGAATAAGTAAATGAACAAAAGCTGTTAT TTTTTTTCTTTGCTCAACCACTCTTCTCTTAAATTCTTGGGATAGAAAAGAGGACTTAAA AGAAGTTTCAGTGTGGAACAGACATTTCTTACCATTTTCCCCATTTCATCTTTTCCAGCA CAAGCCCTGTAGGTATAAAGTTTGACTTGTGATTTCAGAAAGGCAGACAGTGGAAGAGGA TGGCTGCAAAGCAGTTCAAGAGGTACACACCAAGTAAGCACAGGTTCTCTCATCAGATTC TAGACTCTCTAAAAACCAGGTCCCCGAAGTCTGCAAAGGCAAGTAAGGACAATAAGGAGT TTCCTCCATGTGCCGAGCTGTATAGGTTACAAAGTGCACAGGAAGGCGGGGAGGGCAGGG TACCAAGGGCACAGTCAATCAGAGACCTGCGACAGACTAAGGAAATGAAGAAGCCCAGAG AAGAGAAAGCACTTGCCAAAGTCACAGAGCTAGTTCAAGGCAGACCTGGGAAAAGAGCCC CATCCCCTAACCTTCTAATGCTGAGTCCACAAAACTTCACTCCACCAGGCTGCCTGTCTA GAATGTAAAGCAGTTGTTACACTGAGTTCTGTAAAGCTGCGGTTAAGTAGGTTCACGAAG AAAGTTTACTGAGAGGTAGTTTCAACCAGGTTACCAAAGGACCTTAGAAATAATCAGCAT TTAATTCTAACCACTCTCACCCACCAGTCAGGGTTGATGAACCACACTTCTGAATGAGAG AGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGGCGGGGGGGGGGGGGGGGGAGGAAAGAGG GAGGGGGAGAGAAAAGGACGGAAGGAAGGAGGAAGGGCGGGAGAGAAAGGGAGAGGGAGA GGAAGGGGGGAGGAAGAGGGAGCGGGGAGAGAGAGAGAGAAGAGAGGGAGGGGGAGAGAG AGAAAGGGAGAGGGAGAGGAAGGGGGGAGGGAGAGGGAGTGGGGAGAGAGGGAGGGTGGG GAGAGAGAGAGAGAGAGAGAGAACTTCTTAGAGTACTTCTTCCCAGGGACCTGGTATTAT CTGGTCCCTGTTAACACCTGCACTCAAAATAATTCACCTCTTTGAGATCAGATAATGAGT TAAAAATTCATTTAGGATGAGCTGAATGTCAGAGCATAAAAGCCTCAACTCTAACCTGCA GTGGAAGAGCCAGAGGTGAGTGATTTACACCTAACCCTCTGCAGAACAAGAACACAGTGT TCTGATTTCTAGGTTCCTGCAGGTTCCCTCAAACCTGCTGCTGAGACACACCCATGTTTC TAAAAGAATGCATGTACTAGATATTCCAGGCTCAGCCCAGATACTTCCATTCTTTAGTTC TCCTTCAGTCATTCATTCACTCAAGGAGTAAGTGTGGAGTGAATGTACACTGCAGATGCC ACAGAGACTTAAAAAACCCTGAGCCCCTGCCTTCGGAGGGTCGTTCAGGCCATCTTTACG TTTCCCGAGGTGCCCATCCTACCTGGGGGCCCTACCCCGAGCAACAGTTCAATCATCTCT GCTGGGAGCTGCAGTAGGCGGCAGAAAGGAATGGTTAGGAGGGTTCAAATCTCGGCTCTA CTACCACTTAAGCAGCTGTGCAAGAGGCTCCACGTCTCCGAACCTCAAGTGTCCTCATCT GTAAAGTGTTGAGAAGAATAGCACCTTCTTCACAAGGCTGTTAGCAGGCGGAGATTACGA ACAATGCTGAGGGCTCGGTATACAGTAGCTCCTCTGCTGTTCCTCGTTTTGTTTTCAATT GTTGACCGAAAAGAAGGAAGGGAGACTGGCAGGAGACGCAGGAGCGGCGCGCCCCGCAAA GTCAGGGAGGTTCCTCGGCCTCACCTCTGGACTCCCCTCGGAATGGTCCGCAAGGACGGG GCCAGAGCCCCCCAAATCTCTAAGCGGTGGAGGGGAGCTGAACGGCTCCAGCTTGGGATT TGGGACTCAGGACGGCCGAGGAACCCGTGAAGGCCGCGACCGTGGCCTTCACCCTGCTAG GCCTCCTCAGTACCAACACTCACCATGATTGCGGCGGTGGCTGCTCCAGGTCTCGGACGT GGCAGCTCCCGGCGGCGCCTCGGAAC bcftools-1.21/test/csq/ENST00000422159/ENST00000422159.fa.fai000066400000000000000000000000211467060157400215260ustar00rootroot000000000000003 35546 23 60 61 bcftools-1.21/test/csq/ENST00000422159/ENST00000422159.gff000066400000000000000000001577241467060157400211730ustar00rootroot000000000000003 Ensembl chromosome -10285565 188009993 . . . ID=chromosome:3;Alias=CM000665.2,chr3,NC_000003.12 3 ensembl_havana gene 100 7381 . - . ID=gene:ENSG00000157017;Name=GHRL;biotype=protein_coding;description=ghrelin and obestatin prepropeptide [Source:HGNC Symbol%3BAcc:HGNC:18129];gene_id=ENSG00000157017;logic_name=ensembl_havana_gene_homo_sapiens;version=16 3 ensembl_havana mRNA 100 7381 . - . ID=transcript:ENST00000335542;Parent=gene:ENSG00000157017;Name=GHRL-202;biotype=protein_coding;ccdsid=CCDS33700.1;tag=basic;transcript_id=ENST00000335542;transcript_support_level=1 (assigned to previous version 12);version=13 3 ensembl_havana three_prime_UTR 100 308 . - . Parent=transcript:ENST00000335542 3 ensembl_havana exon 100 328 . - . Parent=transcript:ENST00000335542;Name=ENSE00001812025;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001812025;rank=6;version=2 3 ensembl_havana CDS 309 328 . - 2 ID=CDS:ENSP00000335074;Parent=transcript:ENST00000335542;protein_id=ENSP00000335074 3 ensembl_havana exon 1138 1246 . - . Parent=transcript:ENST00000335542;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=5;version=1 3 ensembl_havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000335074;Parent=transcript:ENST00000335542;protein_id=ENSP00000335074 3 ensembl_havana exon 4196 4312 . - . Parent=transcript:ENST00000335542;Name=ENSE00003542562;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003542562;rank=4;version=1 3 ensembl_havana CDS 4196 4312 . - 0 ID=CDS:ENSP00000335074;Parent=transcript:ENST00000335542;protein_id=ENSP00000335074 3 ensembl_havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000335074;Parent=transcript:ENST00000335542;protein_id=ENSP00000335074 3 ensembl_havana exon 4507 4643 . - . Parent=transcript:ENST00000335542;Name=ENSE00001386954;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001386954;rank=3;version=3 3 ensembl_havana five_prime_UTR 4615 4643 . - . Parent=transcript:ENST00000335542 3 ensembl_havana exon 5150 5885 . - . Parent=transcript:ENST00000335542;Name=ENSE00001547498;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001547498;rank=2;version=1 3 ensembl_havana five_prime_UTR 5150 5885 . - . Parent=transcript:ENST00000335542 3 ensembl_havana exon 7276 7381 . - . Parent=transcript:ENST00000335542;Name=ENSE00002106906;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002106906;rank=1;version=1 3 ensembl_havana five_prime_UTR 7276 7381 . - . Parent=transcript:ENST00000335542 3 havana lnc_RNA 184 4791 . - . ID=transcript:ENST00000481287;Parent=gene:ENSG00000157017;Name=GHRL-214;biotype=retained_intron;transcript_id=ENST00000481287;transcript_support_level=1;version=5 3 havana exon 184 328 . - . Parent=transcript:ENST00000481287;Name=ENSE00003481797;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003481797;rank=4;version=1 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000481287;Name=ENSE00003573261;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003573261;rank=3;version=1 3 havana exon 4196 4312 . - . Parent=transcript:ENST00000481287;Name=ENSE00003586371;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003586371;rank=2;version=1 3 havana exon 4507 4791 . - . Parent=transcript:ENST00000481287;Name=ENSE00001884238;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001884238;rank=1;version=1 3 havana lnc_RNA 184 5348 . - . ID=transcript:ENST00000491589;Parent=gene:ENSG00000157017;Name=GHRL-215;biotype=processed_transcript;transcript_id=ENST00000491589;transcript_support_level=3;version=5 3 havana exon 184 328 . - . Parent=transcript:ENST00000491589;Name=ENSE00003481797;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003481797;rank=4;version=1 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000491589;Name=ENSE00003573261;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003573261;rank=3;version=1 3 havana exon 4196 4312 . - . Parent=transcript:ENST00000491589;Name=ENSE00003586371;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003586371;rank=2;version=1 3 havana exon 5150 5348 . - . Parent=transcript:ENST00000491589;Name=ENSE00001859309;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001859309;rank=1;version=1 3 havana mRNA 184 7351 . - . ID=transcript:ENST00000430179;Parent=gene:ENSG00000157017;Name=GHRL-206;biotype=protein_coding;ccdsid=CCDS46750.1;tag=basic;transcript_id=ENST00000430179;transcript_support_level=1;version=5 3 havana three_prime_UTR 184 308 . - . Parent=transcript:ENST00000430179 3 havana exon 184 328 . - . Parent=transcript:ENST00000430179;Name=ENSE00003688374;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003688374;rank=6;version=1 3 havana CDS 309 328 . - 2 ID=CDS:ENSP00000399922;Parent=transcript:ENST00000430179;protein_id=ENSP00000399922 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000430179;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=5;version=1 3 havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000399922;Parent=transcript:ENST00000430179;protein_id=ENSP00000399922 3 havana exon 4196 4309 . - . Parent=transcript:ENST00000430179;Name=ENSE00001752890;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001752890;rank=4;version=1 3 havana CDS 4196 4309 . - 0 ID=CDS:ENSP00000399922;Parent=transcript:ENST00000430179;protein_id=ENSP00000399922 3 havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000399922;Parent=transcript:ENST00000430179;protein_id=ENSP00000399922 3 havana exon 4507 4643 . - . Parent=transcript:ENST00000430179;Name=ENSE00001386954;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001386954;rank=3;version=3 3 havana five_prime_UTR 4615 4643 . - . Parent=transcript:ENST00000430179 3 havana exon 5150 5424 . - . Parent=transcript:ENST00000430179;Name=ENSE00001613470;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001613470;rank=2;version=1 3 havana five_prime_UTR 5150 5424 . - . Parent=transcript:ENST00000430179 3 havana exon 7276 7351 . - . Parent=transcript:ENST00000430179;Name=ENSE00003550699;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003550699;rank=1;version=1 3 havana five_prime_UTR 7276 7351 . - . Parent=transcript:ENST00000430179 3 havana mRNA 185 4646 . - . ID=transcript:ENST00000422159;Parent=gene:ENSG00000157017;Name=GHRL-203;biotype=protein_coding;tag=basic;transcript_id=ENST00000422159;transcript_support_level=1;version=5 3 havana three_prime_UTR 185 277 . - . Parent=transcript:ENST00000422159 3 havana exon 185 328 . - . Parent=transcript:ENST00000422159;Name=ENSE00003558112;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003558112;rank=3;version=1 3 havana CDS 278 328 . - 0 ID=CDS:ENSP00000405464;Parent=transcript:ENST00000422159;protein_id=ENSP00000405464 3 havana exon 4196 4312 . - . Parent=transcript:ENST00000422159;Name=ENSE00003542562;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003542562;rank=2;version=1 3 havana CDS 4196 4312 . - 0 ID=CDS:ENSP00000405464;Parent=transcript:ENST00000422159;protein_id=ENSP00000405464 3 havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000405464;Parent=transcript:ENST00000422159;protein_id=ENSP00000405464 3 havana exon 4507 4646 . - . Parent=transcript:ENST00000422159;Name=ENSE00001747893;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001747893;rank=1;version=1 3 havana five_prime_UTR 4615 4646 . - . Parent=transcript:ENST00000422159 3 havana mRNA 188 7351 . - . ID=transcript:ENST00000449238;Parent=gene:ENSG00000157017;Name=GHRL-210;biotype=protein_coding;ccdsid=CCDS46749.1;tag=basic;transcript_id=ENST00000449238;transcript_support_level=1;version=6 3 havana three_prime_UTR 188 308 . - . Parent=transcript:ENST00000449238 3 havana exon 188 328 . - . Parent=transcript:ENST00000449238;Name=ENSE00003486035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003486035;rank=4;version=1 3 havana CDS 309 328 . - 2 ID=CDS:ENSP00000388145;Parent=transcript:ENST00000449238;protein_id=ENSP00000388145 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000449238;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=3;version=1 3 havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000388145;Parent=transcript:ENST00000449238;protein_id=ENSP00000388145 3 havana exon 4196 4309 . - . Parent=transcript:ENST00000449238;Name=ENSE00001752890;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001752890;rank=2;version=1 3 havana CDS 4196 4309 . - 0 ID=CDS:ENSP00000388145;Parent=transcript:ENST00000449238;protein_id=ENSP00000388145 3 havana CDS 7276 7347 . - 0 ID=CDS:ENSP00000388145;Parent=transcript:ENST00000449238;protein_id=ENSP00000388145 3 havana exon 7276 7351 . - . Parent=transcript:ENST00000449238;Name=ENSE00003687824;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003687824;rank=1;version=1 3 havana five_prime_UTR 7348 7351 . - . Parent=transcript:ENST00000449238 3 ensembl_havana mRNA 188 7351 . - . ID=transcript:ENST00000437422;Parent=gene:ENSG00000157017;Name=GHRL-207;biotype=protein_coding;ccdsid=CCDS46748.1;tag=basic;transcript_id=ENST00000437422;transcript_support_level=1;version=6 3 ensembl_havana three_prime_UTR 188 308 . - . Parent=transcript:ENST00000437422 3 ensembl_havana exon 188 328 . - . Parent=transcript:ENST00000437422;Name=ENSE00003486035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003486035;rank=4;version=1 3 ensembl_havana CDS 309 328 . - 2 ID=CDS:ENSP00000416768;Parent=transcript:ENST00000437422;protein_id=ENSP00000416768 3 ensembl_havana exon 1138 1246 . - . Parent=transcript:ENST00000437422;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=3;version=1 3 ensembl_havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000416768;Parent=transcript:ENST00000437422;protein_id=ENSP00000416768 3 ensembl_havana exon 4196 4312 . - . Parent=transcript:ENST00000437422;Name=ENSE00003542562;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003542562;rank=2;version=1 3 ensembl_havana CDS 4196 4312 . - 0 ID=CDS:ENSP00000416768;Parent=transcript:ENST00000437422;protein_id=ENSP00000416768 3 ensembl_havana CDS 7276 7347 . - 0 ID=CDS:ENSP00000416768;Parent=transcript:ENST00000437422;protein_id=ENSP00000416768 3 ensembl_havana exon 7276 7351 . - . Parent=transcript:ENST00000437422;Name=ENSE00003687824;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003687824;rank=1;version=1 3 ensembl_havana five_prime_UTR 7348 7351 . - . Parent=transcript:ENST00000437422 3 havana mRNA 188 7351 . - . ID=transcript:ENST00000287656;Parent=gene:ENSG00000157017;Name=GHRL-201;biotype=protein_coding;ccdsid=CCDS46750.1;tag=basic;transcript_id=ENST00000287656;transcript_support_level=1;version=11 3 havana three_prime_UTR 188 308 . - . Parent=transcript:ENST00000287656 3 havana exon 188 328 . - . Parent=transcript:ENST00000287656;Name=ENSE00003486035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003486035;rank=6;version=1 3 havana CDS 309 328 . - 2 ID=CDS:ENSP00000287656;Parent=transcript:ENST00000287656;protein_id=ENSP00000287656 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000287656;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=5;version=1 3 havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000287656;Parent=transcript:ENST00000287656;protein_id=ENSP00000287656 3 havana exon 4196 4309 . - . Parent=transcript:ENST00000287656;Name=ENSE00001752890;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001752890;rank=4;version=1 3 havana CDS 4196 4309 . - 0 ID=CDS:ENSP00000287656;Parent=transcript:ENST00000287656;protein_id=ENSP00000287656 3 havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000287656;Parent=transcript:ENST00000287656;protein_id=ENSP00000287656 3 havana exon 4507 4643 . - . Parent=transcript:ENST00000287656;Name=ENSE00001386954;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001386954;rank=3;version=3 3 havana five_prime_UTR 4615 4643 . - . Parent=transcript:ENST00000287656 3 havana exon 5150 5885 . - . Parent=transcript:ENST00000287656;Name=ENSE00001547498;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001547498;rank=2;version=1 3 havana five_prime_UTR 5150 5885 . - . Parent=transcript:ENST00000287656 3 havana exon 7276 7351 . - . Parent=transcript:ENST00000287656;Name=ENSE00003550699;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003550699;rank=1;version=1 3 havana five_prime_UTR 7276 7351 . - . Parent=transcript:ENST00000287656 3 havana mRNA 188 7351 . - . ID=transcript:ENST00000457360;Parent=gene:ENSG00000157017;Name=GHRL-211;biotype=protein_coding;ccdsid=CCDS33700.1;tag=basic;transcript_id=ENST00000457360;transcript_support_level=1;version=5 3 havana three_prime_UTR 188 308 . - . Parent=transcript:ENST00000457360 3 havana exon 188 328 . - . Parent=transcript:ENST00000457360;Name=ENSE00003486035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003486035;rank=6;version=1 3 havana CDS 309 328 . - 2 ID=CDS:ENSP00000391406;Parent=transcript:ENST00000457360;protein_id=ENSP00000391406 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000457360;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=5;version=1 3 havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000391406;Parent=transcript:ENST00000457360;protein_id=ENSP00000391406 3 havana exon 4196 4312 . - . Parent=transcript:ENST00000457360;Name=ENSE00003542562;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003542562;rank=4;version=1 3 havana CDS 4196 4312 . - 0 ID=CDS:ENSP00000391406;Parent=transcript:ENST00000457360;protein_id=ENSP00000391406 3 havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000391406;Parent=transcript:ENST00000457360;protein_id=ENSP00000391406 3 havana exon 4507 4643 . - . Parent=transcript:ENST00000457360;Name=ENSE00001386954;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001386954;rank=3;version=3 3 havana five_prime_UTR 4615 4643 . - . Parent=transcript:ENST00000457360 3 havana exon 5150 5424 . - . Parent=transcript:ENST00000457360;Name=ENSE00001613470;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001613470;rank=2;version=1 3 havana five_prime_UTR 5150 5424 . - . Parent=transcript:ENST00000457360 3 havana exon 7276 7351 . - . Parent=transcript:ENST00000457360;Name=ENSE00003550699;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003550699;rank=1;version=1 3 havana five_prime_UTR 7276 7351 . - . Parent=transcript:ENST00000457360 3 ensembl_havana mRNA 188 7351 . - . ID=transcript:ENST00000439975;Parent=gene:ENSG00000157017;Name=GHRL-208;biotype=protein_coding;ccdsid=CCDS46747.1;tag=basic;transcript_id=ENST00000439975;transcript_support_level=1;version=6 3 ensembl_havana three_prime_UTR 188 308 . - . Parent=transcript:ENST00000439975 3 ensembl_havana exon 188 328 . - . Parent=transcript:ENST00000439975;Name=ENSE00003486035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003486035;rank=3;version=1 3 ensembl_havana CDS 309 328 . - 2 ID=CDS:ENSP00000403725;Parent=transcript:ENST00000439975;protein_id=ENSP00000403725 3 ensembl_havana exon 1138 1246 . - . Parent=transcript:ENST00000439975;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=2;version=1 3 ensembl_havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000403725;Parent=transcript:ENST00000439975;protein_id=ENSP00000403725 3 ensembl_havana CDS 7276 7347 . - 0 ID=CDS:ENSP00000403725;Parent=transcript:ENST00000439975;protein_id=ENSP00000403725 3 ensembl_havana exon 7276 7351 . - . Parent=transcript:ENST00000439975;Name=ENSE00003687824;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003687824;rank=1;version=1 3 ensembl_havana five_prime_UTR 7348 7351 . - . Parent=transcript:ENST00000439975 3 ensembl_havana mRNA 188 7351 . - . ID=transcript:ENST00000446937;Parent=gene:ENSG00000157017;Name=GHRL-209;biotype=protein_coding;tag=basic;transcript_id=ENST00000446937;transcript_support_level=1;version=2 3 ensembl_havana three_prime_UTR 188 277 . - . Parent=transcript:ENST00000446937 3 ensembl_havana exon 188 328 . - . Parent=transcript:ENST00000446937;Name=ENSE00003584193;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003584193;rank=2;version=1 3 ensembl_havana CDS 278 328 . - 0 ID=CDS:ENSP00000394923;Parent=transcript:ENST00000446937;protein_id=ENSP00000394923 3 ensembl_havana CDS 7276 7347 . - 0 ID=CDS:ENSP00000394923;Parent=transcript:ENST00000446937;protein_id=ENSP00000394923 3 ensembl_havana exon 7276 7351 . - . Parent=transcript:ENST00000446937;Name=ENSE00003687824;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003687824;rank=1;version=1 3 ensembl_havana five_prime_UTR 7348 7351 . - . Parent=transcript:ENST00000446937 3 havana mRNA 188 7367 . - . ID=transcript:ENST00000429122;Parent=gene:ENSG00000157017;Name=GHRL-205;biotype=protein_coding;ccdsid=CCDS33700.1;tag=basic;transcript_id=ENST00000429122;transcript_support_level=1;version=1 3 havana three_prime_UTR 188 308 . - . Parent=transcript:ENST00000429122 3 havana exon 188 328 . - . Parent=transcript:ENST00000429122;Name=ENSE00003486035;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003486035;rank=6;version=1 3 havana CDS 309 328 . - 2 ID=CDS:ENSP00000414819;Parent=transcript:ENST00000429122;protein_id=ENSP00000414819 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000429122;Name=ENSE00003637018;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003637018;rank=5;version=1 3 havana CDS 1138 1246 . - 0 ID=CDS:ENSP00000414819;Parent=transcript:ENST00000429122;protein_id=ENSP00000414819 3 havana exon 4196 4312 . - . Parent=transcript:ENST00000429122;Name=ENSE00003542562;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003542562;rank=4;version=1 3 havana CDS 4196 4312 . - 0 ID=CDS:ENSP00000414819;Parent=transcript:ENST00000429122;protein_id=ENSP00000414819 3 havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000414819;Parent=transcript:ENST00000429122;protein_id=ENSP00000414819 3 havana exon 4507 4643 . - . Parent=transcript:ENST00000429122;Name=ENSE00001386954;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001386954;rank=3;version=3 3 havana five_prime_UTR 4615 4643 . - . Parent=transcript:ENST00000429122 3 havana exon 5150 5346 . - . Parent=transcript:ENST00000429122;Name=ENSE00001767870;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001767870;rank=2;version=1 3 havana five_prime_UTR 5150 5346 . - . Parent=transcript:ENST00000429122 3 havana exon 7276 7367 . - . Parent=transcript:ENST00000429122;Name=ENSE00001634545;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001634545;rank=1;version=1 3 havana five_prime_UTR 7276 7367 . - . Parent=transcript:ENST00000429122 3 havana lnc_RNA 247 4241 . - . ID=transcript:ENST00000475759;Parent=gene:ENSG00000157017;Name=GHRL-212;biotype=processed_transcript;transcript_id=ENST00000475759;transcript_support_level=1;version=5 3 havana exon 247 328 . - . Parent=transcript:ENST00000475759;Name=ENSE00001839829;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001839829;rank=4;version=1 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000475759;Name=ENSE00003573261;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003573261;rank=3;version=1 3 havana exon 1462 1760 . - . Parent=transcript:ENST00000475759;Name=ENSE00001873139;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001873139;rank=2;version=1 3 havana exon 4196 4241 . - . Parent=transcript:ENST00000475759;Name=ENSE00001876814;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001876814;rank=1;version=1 3 havana lnc_RNA 247 4241 . - . ID=transcript:ENST00000476283;Parent=gene:ENSG00000157017;Name=GHRL-213;biotype=processed_transcript;transcript_id=ENST00000476283;transcript_support_level=1;version=1 3 havana exon 247 328 . - . Parent=transcript:ENST00000476283;Name=ENSE00001839829;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001839829;rank=5;version=1 3 havana exon 1138 1246 . - . Parent=transcript:ENST00000476283;Name=ENSE00003573261;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003573261;rank=4;version=1 3 havana exon 1462 1760 . - . Parent=transcript:ENST00000476283;Name=ENSE00001873139;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001873139;rank=3;version=1 3 havana exon 2459 2650 . - . Parent=transcript:ENST00000476283;Name=ENSE00001907767;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001907767;rank=2;version=1 3 havana exon 4196 4241 . - . Parent=transcript:ENST00000476283;Name=ENSE00001876814;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001876814;rank=1;version=1 3 havana mRNA 4514 7372 . - . ID=transcript:ENST00000425479;Parent=gene:ENSG00000157017;Name=GHRL-204;biotype=protein_coding;transcript_id=ENST00000425479;transcript_support_level=1;version=1 3 havana CDS 4514 4614 . - 0 ID=CDS:ENSP00000405031;Parent=transcript:ENST00000425479;protein_id=ENSP00000405031 3 havana exon 4514 4643 . - . Parent=transcript:ENST00000425479;Name=ENSE00001791415;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001791415;rank=2;version=1 3 havana five_prime_UTR 4615 4643 . - . Parent=transcript:ENST00000425479 3 havana exon 7276 7372 . - . Parent=transcript:ENST00000425479;Name=ENSE00001718935;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001718935;rank=1;version=1 3 havana five_prime_UTR 7276 7372 . - . Parent=transcript:ENST00000425479 3 havana ncRNA_gene 188 9337 . + . ID=gene:ENSG00000240288;Name=GHRLOS;biotype=lncRNA;description=ghrelin opposite strand/antisense RNA [Source:HGNC Symbol%3BAcc:HGNC:33885];gene_id=ENSG00000240288;logic_name=havana_homo_sapiens;version=8 3 havana lnc_RNA 188 7351 . + . ID=transcript:ENST00000605014;Parent=gene:ENSG00000240288;Name=GHRLOS-203;biotype=lncRNA;transcript_id=ENST00000605014;transcript_support_level=1;version=5 3 havana exon 188 287 . + . Parent=transcript:ENST00000605014;Name=ENSE00001614716;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001614716;rank=1;version=2 3 havana exon 1848 1915 . + . Parent=transcript:ENST00000605014;Name=ENSE00001620959;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001620959;rank=2;version=1 3 havana exon 2379 2536 . + . Parent=transcript:ENST00000605014;Name=ENSE00001778021;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001778021;rank=3;version=1 3 havana exon 6757 7351 . + . Parent=transcript:ENST00000605014;Name=ENSE00003569541;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003569541;rank=4;version=1 3 havana lnc_RNA 188 7351 . + . ID=transcript:ENST00000605105;Parent=gene:ENSG00000240288;Name=GHRLOS-204;biotype=lncRNA;transcript_id=ENST00000605105;transcript_support_level=1;version=5 3 havana exon 188 287 . + . Parent=transcript:ENST00000605105;Name=ENSE00001614716;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001614716;rank=1;version=2 3 havana exon 6502 7351 . + . Parent=transcript:ENST00000605105;Name=ENSE00003465499;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003465499;rank=2;version=1 3 havana lnc_RNA 188 7883 . + . ID=transcript:ENST00000439539;Parent=gene:ENSG00000240288;Name=GHRLOS-201;biotype=lncRNA;tag=basic;transcript_id=ENST00000439539;transcript_support_level=1;version=3 3 havana exon 188 287 . + . Parent=transcript:ENST00000439539;Name=ENSE00001614716;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001614716;rank=1;version=2 3 havana exon 1848 1915 . + . Parent=transcript:ENST00000439539;Name=ENSE00001620959;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001620959;rank=2;version=1 3 havana exon 2379 2536 . + . Parent=transcript:ENST00000439539;Name=ENSE00001778021;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001778021;rank=3;version=1 3 havana exon 6502 7883 . + . Parent=transcript:ENST00000439539;Name=ENSE00003695075;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003695075;rank=4;version=1 3 havana_tagene lnc_RNA 2391 9337 . + . ID=transcript:ENST00000662597;Parent=gene:ENSG00000240288;Name=GHRLOS-205;biotype=lncRNA;tag=basic;transcript_id=ENST00000662597;version=1 3 havana_tagene exon 2391 2540 . + . Parent=transcript:ENST00000662597;Name=ENSE00003861779;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003861779;rank=1;version=1 3 havana_tagene exon 6502 9337 . + . Parent=transcript:ENST00000662597;Name=ENSE00003873900;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003873900;rank=2;version=1 3 havana lnc_RNA 2412 7014 . + . ID=transcript:ENST00000603771;Parent=gene:ENSG00000240288;Name=GHRLOS-202;biotype=lncRNA;transcript_id=ENST00000603771;transcript_support_level=5;version=1 3 havana exon 2412 2540 . + . Parent=transcript:ENST00000603771;Name=ENSE00003515781;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003515781;rank=1;version=1 3 havana exon 6502 7014 . + . Parent=transcript:ENST00000603771;Name=ENSE00001674235;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001674235;rank=2;version=2 3 ensembl ncRNA_gene 1847 1916 . + . ID=gene:ENSG00000276678;Name=AC022384.2;biotype=misc_RNA;gene_id=ENSG00000276678;logic_name=ncrna_homo_sapiens;version=1 3 ensembl ncRNA 1847 1916 . + . ID=transcript:ENST00000610995;Parent=gene:ENSG00000276678;Name=AC022384.2-201;biotype=misc_RNA;tag=basic;transcript_id=ENST00000610995;transcript_support_level=NA;version=1 3 ensembl exon 1847 1916 . + . Parent=transcript:ENST00000610995;Name=ENSE00003727327;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003727327;rank=1;version=1 3 . biological_region 7276 7445 0.866 - . external_name=rank %3D 1;logic_name=firstef 3 ensembl_havana gene 7565 35546 . - . ID=gene:ENSG00000157020;Name=SEC13;biotype=protein_coding;description=SEC13 homolog%2C nuclear pore and COPII coat complex component [Source:HGNC Symbol%3BAcc:HGNC:10697];gene_id=ENSG00000157020;logic_name=ensembl_havana_gene_homo_sapiens;version=18 3 havana lnc_RNA 7565 19506 . - . ID=transcript:ENST00000492602;Parent=gene:ENSG00000157020;Name=SEC13-219;biotype=processed_transcript;transcript_id=ENST00000492602;transcript_support_level=3;version=5 3 havana exon 7565 7770 . - . Parent=transcript:ENST00000492602;Name=ENSE00001920765;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001920765;rank=3;version=1 3 havana exon 18460 18606 . - . Parent=transcript:ENST00000492602;Name=ENSE00003629896;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003629896;rank=2;version=1 3 havana exon 19467 19506 . - . Parent=transcript:ENST00000492602;Name=ENSE00001945263;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001945263;rank=1;version=1 3 ensembl_havana mRNA 15365 35475 . - . ID=transcript:ENST00000397109;Parent=gene:ENSG00000157020;Name=SEC13-208;biotype=protein_coding;ccdsid=CCDS46751.1;tag=basic;transcript_id=ENST00000397109;transcript_support_level=1;version=7 3 ensembl_havana three_prime_UTR 15365 15694 . - . Parent=transcript:ENST00000397109 3 ensembl_havana exon 15365 15808 . - . Parent=transcript:ENST00000397109;Name=ENSE00001029794;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001029794;rank=9;version=4 3 ensembl_havana CDS 15695 15808 . - 0 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 18460 18606 . - . Parent=transcript:ENST00000397109;Name=ENSE00003652241;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003652241;rank=8;version=1 3 ensembl_havana CDS 18460 18606 . - 0 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 19467 19590 . - . Parent=transcript:ENST00000397109;Name=ENSE00003692347;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003692347;rank=7;version=1 3 ensembl_havana CDS 19467 19590 . - 1 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 19993 20126 . - . Parent=transcript:ENST00000397109;Name=ENSE00003486763;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003486763;rank=6;version=1 3 ensembl_havana CDS 19993 20126 . - 0 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 26399 26532 . - . Parent=transcript:ENST00000397109;Name=ENSE00003679202;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679202;rank=5;version=1 3 ensembl_havana CDS 26399 26532 . - 2 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 27013 27164 . - . Parent=transcript:ENST00000397109;Name=ENSE00003618484;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003618484;rank=4;version=1 3 ensembl_havana CDS 27013 27164 . - 1 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 29755 29870 . - . Parent=transcript:ENST00000397109;Name=ENSE00003686780;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003686780;rank=3;version=1 3 ensembl_havana CDS 29755 29870 . - 0 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana CDS 32484 32489 . - 0 ID=CDS:ENSP00000380298;Parent=transcript:ENST00000397109;protein_id=ENSP00000380298 3 ensembl_havana exon 32484 32528 . - . Parent=transcript:ENST00000397109;Name=ENSE00003692575;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003692575;rank=2;version=1 3 ensembl_havana five_prime_UTR 32490 32528 . - . Parent=transcript:ENST00000397109 3 ensembl_havana exon 35305 35475 . - . Parent=transcript:ENST00000397109;Name=ENSE00001527310;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001527310;rank=1;version=1 3 ensembl_havana five_prime_UTR 35305 35475 . - . Parent=transcript:ENST00000397109 3 havana mRNA 15365 35516 . - . ID=transcript:ENST00000337354;Parent=gene:ENSG00000157020;Name=SEC13-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000337354;transcript_support_level=1;version=8 3 havana three_prime_UTR 15365 15694 . - . Parent=transcript:ENST00000337354 3 havana exon 15365 15808 . - . Parent=transcript:ENST00000337354;Name=ENSE00001029794;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001029794;rank=10;version=4 3 havana CDS 15695 15808 . - 0 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 18460 18606 . - . Parent=transcript:ENST00000337354;Name=ENSE00003652241;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003652241;rank=9;version=1 3 havana CDS 18460 18606 . - 0 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 19467 19590 . - . Parent=transcript:ENST00000337354;Name=ENSE00003692347;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003692347;rank=8;version=1 3 havana CDS 19467 19590 . - 1 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 19993 20126 . - . Parent=transcript:ENST00000337354;Name=ENSE00003486763;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003486763;rank=7;version=1 3 havana CDS 19993 20126 . - 0 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 26399 26532 . - . Parent=transcript:ENST00000337354;Name=ENSE00003679202;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679202;rank=6;version=1 3 havana CDS 26399 26532 . - 2 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 27013 27164 . - . Parent=transcript:ENST00000337354;Name=ENSE00003618484;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003618484;rank=5;version=1 3 havana CDS 27013 27164 . - 1 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 29755 29870 . - . Parent=transcript:ENST00000337354;Name=ENSE00003686780;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003686780;rank=4;version=1 3 havana CDS 29755 29870 . - 0 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000337354;Name=ENSE00003646435;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003646435;rank=3;version=1 3 havana CDS 32484 32528 . - 0 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana CDS 33573 33584 . - 0 ID=CDS:ENSP00000336566;Parent=transcript:ENST00000337354;protein_id=ENSP00000336566 3 havana exon 33573 33606 . - . Parent=transcript:ENST00000337354;Name=ENSE00003508864;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003508864;rank=2;version=1 3 havana five_prime_UTR 33585 33606 . - . Parent=transcript:ENST00000337354 3 havana exon 35484 35516 . - . Parent=transcript:ENST00000337354;Name=ENSE00001498742;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001498742;rank=1;version=1 3 havana five_prime_UTR 35484 35516 . - . Parent=transcript:ENST00000337354 3 ensembl_havana mRNA 15365 35546 . - . ID=transcript:ENST00000350697;Parent=gene:ENSG00000157020;Name=SEC13-202;biotype=protein_coding;ccdsid=CCDS2599.1;tag=basic;transcript_id=ENST00000350697;transcript_support_level=1 (assigned to previous version 7);version=8 3 ensembl_havana three_prime_UTR 15365 15694 . - . Parent=transcript:ENST00000350697 3 ensembl_havana exon 15365 15808 . - . Parent=transcript:ENST00000350697;Name=ENSE00001029794;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001029794;rank=9;version=4 3 ensembl_havana CDS 15695 15808 . - 0 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 18460 18606 . - . Parent=transcript:ENST00000350697;Name=ENSE00003652241;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003652241;rank=8;version=1 3 ensembl_havana CDS 18460 18606 . - 0 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 19467 19590 . - . Parent=transcript:ENST00000350697;Name=ENSE00003692347;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003692347;rank=7;version=1 3 ensembl_havana CDS 19467 19590 . - 1 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 19993 20126 . - . Parent=transcript:ENST00000350697;Name=ENSE00003486763;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003486763;rank=6;version=1 3 ensembl_havana CDS 19993 20126 . - 0 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 26399 26532 . - . Parent=transcript:ENST00000350697;Name=ENSE00003679202;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679202;rank=5;version=1 3 ensembl_havana CDS 26399 26532 . - 2 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 27013 27164 . - . Parent=transcript:ENST00000350697;Name=ENSE00003618484;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003618484;rank=4;version=1 3 ensembl_havana CDS 27013 27164 . - 1 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 29755 29870 . - . Parent=transcript:ENST00000350697;Name=ENSE00003686780;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003686780;rank=3;version=1 3 ensembl_havana CDS 29755 29870 . - 0 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 32484 32528 . - . Parent=transcript:ENST00000350697;Name=ENSE00003646435;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003646435;rank=2;version=1 3 ensembl_havana CDS 32484 32528 . - 0 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana CDS 35484 35486 . - 0 ID=CDS:ENSP00000312122;Parent=transcript:ENST00000350697;protein_id=ENSP00000312122 3 ensembl_havana exon 35484 35546 . - . Parent=transcript:ENST00000350697;Name=ENSE00001397686;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001397686;rank=1;version=3 3 ensembl_havana five_prime_UTR 35487 35546 . - . Parent=transcript:ENST00000350697 3 havana lnc_RNA 15367 28405 . - . ID=transcript:ENST00000479868;Parent=gene:ENSG00000157020;Name=SEC13-216;biotype=retained_intron;transcript_id=ENST00000479868;transcript_support_level=1;version=6 3 havana exon 15367 15808 . - . Parent=transcript:ENST00000479868;Name=ENSE00001885260;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001885260;rank=6;version=1 3 havana exon 18460 18606 . - . Parent=transcript:ENST00000479868;Name=ENSE00003629896;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003629896;rank=5;version=1 3 havana exon 19467 19590 . - . Parent=transcript:ENST00000479868;Name=ENSE00003607241;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003607241;rank=4;version=1 3 havana exon 19993 20126 . - . Parent=transcript:ENST00000479868;Name=ENSE00003693502;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003693502;rank=3;version=1 3 havana exon 26399 26532 . - . Parent=transcript:ENST00000479868;Name=ENSE00003630997;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003630997;rank=2;version=1 3 havana exon 27013 28405 . - . Parent=transcript:ENST00000479868;Name=ENSE00001933257;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001933257;rank=1;version=1 3 havana mRNA 15384 35495 . - . ID=transcript:ENST00000397117;Parent=gene:ENSG00000157020;Name=SEC13-209;biotype=protein_coding;tag=basic;transcript_id=ENST00000397117;transcript_support_level=5;version=5 3 havana three_prime_UTR 15384 15539 . - . Parent=transcript:ENST00000397117 3 havana exon 15384 15581 . - . Parent=transcript:ENST00000397117;Name=ENSE00001527343;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001527343;rank=9;version=1 3 havana CDS 15540 15581 . - 0 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 18460 18606 . - . Parent=transcript:ENST00000397117;Name=ENSE00003652241;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003652241;rank=8;version=1 3 havana CDS 18460 18606 . - 0 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 19467 19590 . - . Parent=transcript:ENST00000397117;Name=ENSE00003692347;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003692347;rank=7;version=1 3 havana CDS 19467 19590 . - 1 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 19993 20126 . - . Parent=transcript:ENST00000397117;Name=ENSE00003486763;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003486763;rank=6;version=1 3 havana CDS 19993 20126 . - 0 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 26399 26532 . - . Parent=transcript:ENST00000397117;Name=ENSE00003679202;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679202;rank=5;version=1 3 havana CDS 26399 26532 . - 2 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 27013 27164 . - . Parent=transcript:ENST00000397117;Name=ENSE00003618484;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003618484;rank=4;version=1 3 havana CDS 27013 27164 . - 1 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 29755 29870 . - . Parent=transcript:ENST00000397117;Name=ENSE00003686780;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003686780;rank=3;version=1 3 havana CDS 29755 29870 . - 0 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana CDS 32484 32489 . - 0 ID=CDS:ENSP00000380306;Parent=transcript:ENST00000397117;protein_id=ENSP00000380306 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000397117;Name=ENSE00003692575;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003692575;rank=2;version=1 3 havana five_prime_UTR 32490 32528 . - . Parent=transcript:ENST00000397117 3 havana exon 34943 35495 . - . Parent=transcript:ENST00000397117;Name=ENSE00001527362;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001527362;rank=1;version=1 3 havana five_prime_UTR 34943 35495 . - . Parent=transcript:ENST00000397117 3 ensembl_havana mRNA 15395 35518 . - . ID=transcript:ENST00000383801;Parent=gene:ENSG00000157020;Name=SEC13-203;biotype=protein_coding;ccdsid=CCDS63540.1;tag=basic;transcript_id=ENST00000383801;transcript_support_level=2;version=6 3 ensembl_havana three_prime_UTR 15395 15694 . - . Parent=transcript:ENST00000383801 3 ensembl_havana exon 15395 15808 . - . Parent=transcript:ENST00000383801;Name=ENSE00001527326;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001527326;rank=10;version=1 3 ensembl_havana CDS 15695 15808 . - 0 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 18460 18606 . - . Parent=transcript:ENST00000383801;Name=ENSE00003652241;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003652241;rank=9;version=1 3 ensembl_havana CDS 18460 18606 . - 0 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 19467 19590 . - . Parent=transcript:ENST00000383801;Name=ENSE00003692347;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003692347;rank=8;version=1 3 ensembl_havana CDS 19467 19590 . - 1 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 19993 20126 . - . Parent=transcript:ENST00000383801;Name=ENSE00003486763;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003486763;rank=7;version=1 3 ensembl_havana CDS 19993 20126 . - 0 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 26399 26532 . - . Parent=transcript:ENST00000383801;Name=ENSE00003679202;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679202;rank=6;version=1 3 ensembl_havana CDS 26399 26532 . - 2 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 27013 27164 . - . Parent=transcript:ENST00000383801;Name=ENSE00003618484;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003618484;rank=5;version=1 3 ensembl_havana CDS 27013 27164 . - 1 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 29755 29870 . - . Parent=transcript:ENST00000383801;Name=ENSE00003686780;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003686780;rank=4;version=1 3 ensembl_havana CDS 29755 29870 . - 0 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 32484 32528 . - . Parent=transcript:ENST00000383801;Name=ENSE00003646435;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003646435;rank=3;version=1 3 ensembl_havana CDS 32484 32528 . - 0 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana CDS 33573 33713 . - 0 ID=CDS:ENSP00000373312;Parent=transcript:ENST00000383801;protein_id=ENSP00000373312 3 ensembl_havana exon 33573 33750 . - . Parent=transcript:ENST00000383801;Name=ENSE00003467984;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003467984;rank=2;version=1 3 ensembl_havana five_prime_UTR 33714 33750 . - . Parent=transcript:ENST00000383801 3 ensembl_havana exon 35484 35518 . - . Parent=transcript:ENST00000383801;Name=ENSE00001498743;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001498743;rank=1;version=2 3 ensembl_havana five_prime_UTR 35484 35518 . - . Parent=transcript:ENST00000383801 3 havana lnc_RNA 17985 32514 . - . ID=transcript:ENST00000477547;Parent=gene:ENSG00000157020;Name=SEC13-215;biotype=retained_intron;transcript_id=ENST00000477547;transcript_support_level=2;version=6 3 havana exon 17985 18606 . - . Parent=transcript:ENST00000477547;Name=ENSE00001945105;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001945105;rank=7;version=1 3 havana exon 19467 19590 . - . Parent=transcript:ENST00000477547;Name=ENSE00003607241;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003607241;rank=6;version=1 3 havana exon 19993 20126 . - . Parent=transcript:ENST00000477547;Name=ENSE00003693502;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003693502;rank=5;version=1 3 havana exon 26399 26532 . - . Parent=transcript:ENST00000477547;Name=ENSE00003630997;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003630997;rank=4;version=1 3 havana exon 27013 27164 . - . Parent=transcript:ENST00000477547;Name=ENSE00003583947;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003583947;rank=3;version=1 3 havana exon 29755 29870 . - . Parent=transcript:ENST00000477547;Name=ENSE00003467776;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003467776;rank=2;version=1 3 havana exon 32484 32514 . - . Parent=transcript:ENST00000477547;Name=ENSE00001939921;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001939921;rank=1;version=1 3 havana lnc_RNA 18469 20344 . - . ID=transcript:ENST00000476597;Parent=gene:ENSG00000157020;Name=SEC13-214;biotype=retained_intron;transcript_id=ENST00000476597;transcript_support_level=2;version=1 3 havana exon 18469 18606 . - . Parent=transcript:ENST00000476597;Name=ENSE00001877132;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001877132;rank=3;version=1 3 havana exon 19467 19590 . - . Parent=transcript:ENST00000476597;Name=ENSE00003607241;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003607241;rank=2;version=1 3 havana exon 19993 20344 . - . Parent=transcript:ENST00000476597;Name=ENSE00001889022;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001889022;rank=1;version=1 3 havana lnc_RNA 18545 20144 . - . ID=transcript:ENST00000490283;Parent=gene:ENSG00000157020;Name=SEC13-218;biotype=retained_intron;transcript_id=ENST00000490283;transcript_support_level=2;version=1 3 havana exon 18545 18606 . - . Parent=transcript:ENST00000490283;Name=ENSE00001900563;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001900563;rank=2;version=1 3 havana exon 19467 20144 . - . Parent=transcript:ENST00000490283;Name=ENSE00001858154;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001858154;rank=1;version=1 3 havana lnc_RNA 26007 27268 . - . ID=transcript:ENST00000482647;Parent=gene:ENSG00000157020;Name=SEC13-217;biotype=retained_intron;transcript_id=ENST00000482647;transcript_support_level=2;version=5 3 havana exon 26007 26532 . - . Parent=transcript:ENST00000482647;Name=ENSE00001849151;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001849151;rank=2;version=1 3 havana exon 27013 27268 . - . Parent=transcript:ENST00000482647;Name=ENSE00001839665;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001839665;rank=1;version=1 3 havana lnc_RNA 26007 35527 . - . ID=transcript:ENST00000397105;Parent=gene:ENSG00000157020;Name=SEC13-207;biotype=retained_intron;transcript_id=ENST00000397105;transcript_support_level=2;version=7 3 havana exon 26007 26532 . - . Parent=transcript:ENST00000397105;Name=ENSE00001849151;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001849151;rank=5;version=1 3 havana exon 27013 27164 . - . Parent=transcript:ENST00000397105;Name=ENSE00003583947;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003583947;rank=4;version=1 3 havana exon 29755 29870 . - . Parent=transcript:ENST00000397105;Name=ENSE00003467776;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003467776;rank=3;version=1 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000397105;Name=ENSE00003505650;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003505650;rank=2;version=1 3 havana exon 35484 35527 . - . Parent=transcript:ENST00000397105;Name=ENSE00001902883;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001902883;rank=1;version=1 3 havana mRNA 27080 35494 . - . ID=transcript:ENST00000431352;Parent=gene:ENSG00000157020;Name=SEC13-211;biotype=protein_coding;transcript_id=ENST00000431352;transcript_support_level=5;version=1 3 havana exon 27080 27164 . - . Parent=transcript:ENST00000431352;Name=ENSE00001602494;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001602494;rank=5;version=1 3 havana CDS 27080 27164 . - 1 ID=CDS:ENSP00000401368;Parent=transcript:ENST00000431352;protein_id=ENSP00000401368 3 havana exon 29755 29870 . - . Parent=transcript:ENST00000431352;Name=ENSE00003686780;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003686780;rank=4;version=1 3 havana CDS 29755 29870 . - 0 ID=CDS:ENSP00000401368;Parent=transcript:ENST00000431352;protein_id=ENSP00000401368 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000431352;Name=ENSE00003646435;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003646435;rank=3;version=1 3 havana CDS 32484 32528 . - 0 ID=CDS:ENSP00000401368;Parent=transcript:ENST00000431352;protein_id=ENSP00000401368 3 havana CDS 33573 33584 . - 0 ID=CDS:ENSP00000401368;Parent=transcript:ENST00000431352;protein_id=ENSP00000401368 3 havana exon 33573 33606 . - . Parent=transcript:ENST00000431352;Name=ENSE00003508864;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003508864;rank=2;version=1 3 havana five_prime_UTR 33585 33606 . - . Parent=transcript:ENST00000431352 3 havana exon 34943 35494 . - . Parent=transcript:ENST00000431352;Name=ENSE00001658092;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001658092;rank=1;version=1 3 havana five_prime_UTR 34943 35494 . - . Parent=transcript:ENST00000431352 3 havana lnc_RNA 27514 35546 . - . ID=transcript:ENST00000397102;Parent=gene:ENSG00000157020;Name=SEC13-206;biotype=retained_intron;transcript_id=ENST00000397102;transcript_support_level=3;version=5 3 havana exon 27514 27871 . - . Parent=transcript:ENST00000397102;Name=ENSE00001527292;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001527292;rank=4;version=1 3 havana exon 29755 29870 . - . Parent=transcript:ENST00000397102;Name=ENSE00003467776;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003467776;rank=3;version=1 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000397102;Name=ENSE00003505650;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003505650;rank=2;version=1 3 havana exon 35484 35546 . - . Parent=transcript:ENST00000397102;Name=ENSE00001390788;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001390788;rank=1;version=2 3 havana lnc_RNA 29387 35546 . - . ID=transcript:ENST00000397101;Parent=gene:ENSG00000157020;Name=SEC13-205;biotype=retained_intron;transcript_id=ENST00000397101;transcript_support_level=2;version=5 3 havana exon 29387 29870 . - . Parent=transcript:ENST00000397101;Name=ENSE00001527288;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001527288;rank=3;version=1 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000397101;Name=ENSE00003505650;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003505650;rank=2;version=1 3 havana exon 35484 35546 . - . Parent=transcript:ENST00000397101;Name=ENSE00001390788;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001390788;rank=1;version=2 3 havana lnc_RNA 29576 35520 . - . ID=transcript:ENST00000397099;Parent=gene:ENSG00000157020;Name=SEC13-204;biotype=retained_intron;transcript_id=ENST00000397099;transcript_support_level=4;version=1 3 havana exon 29576 29870 . - . Parent=transcript:ENST00000397099;Name=ENSE00001527284;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001527284;rank=4;version=1 3 havana exon 32484 32528 . - . Parent=transcript:ENST00000397099;Name=ENSE00003505650;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003505650;rank=3;version=1 3 havana exon 33573 33750 . - . Parent=transcript:ENST00000397099;Name=ENSE00003606304;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003606304;rank=2;version=1 3 havana exon 35484 35520 . - . Parent=transcript:ENST00000397099;Name=ENSE00001527285;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001527285;rank=1;version=1 3 havana mRNA 32502 35490 . - . ID=transcript:ENST00000428626;Parent=gene:ENSG00000157020;Name=SEC13-210;biotype=protein_coding;transcript_id=ENST00000428626;transcript_support_level=3;version=5 3 havana exon 32502 32528 . - . Parent=transcript:ENST00000428626;Name=ENSE00001793948;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001793948;rank=4;version=1 3 havana CDS 32502 32528 . - 0 ID=CDS:ENSP00000400260;Parent=transcript:ENST00000428626;protein_id=ENSP00000400260 3 havana exon 33573 33606 . - . Parent=transcript:ENST00000428626;Name=ENSE00003558611;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003558611;rank=3;version=1 3 havana CDS 33573 33606 . - 1 ID=CDS:ENSP00000400260;Parent=transcript:ENST00000428626;protein_id=ENSP00000400260 3 havana CDS 33691 33713 . - 0 ID=CDS:ENSP00000400260;Parent=transcript:ENST00000428626;protein_id=ENSP00000400260 3 havana exon 33691 33750 . - . Parent=transcript:ENST00000428626;Name=ENSE00001699437;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001699437;rank=2;version=1 3 havana five_prime_UTR 33714 33750 . - . Parent=transcript:ENST00000428626 3 havana exon 35045 35490 . - . Parent=transcript:ENST00000428626;Name=ENSE00001783139;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001783139;rank=1;version=1 3 havana five_prime_UTR 35045 35490 . - . Parent=transcript:ENST00000428626 3 havana mRNA 32504 35492 . - . ID=transcript:ENST00000445064;Parent=gene:ENSG00000157020;Name=SEC13-213;biotype=protein_coding;transcript_id=ENST00000445064;transcript_support_level=5;version=1 3 havana exon 32504 32528 . - . Parent=transcript:ENST00000445064;Name=ENSE00001617854;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001617854;rank=4;version=1 3 havana CDS 32504 32528 . - 0 ID=CDS:ENSP00000398623;Parent=transcript:ENST00000445064;protein_id=ENSP00000398623 3 havana exon 33573 33606 . - . Parent=transcript:ENST00000445064;Name=ENSE00003558611;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003558611;rank=3;version=1 3 havana CDS 33573 33606 . - 1 ID=CDS:ENSP00000398623;Parent=transcript:ENST00000445064;protein_id=ENSP00000398623 3 havana CDS 33691 33713 . - 0 ID=CDS:ENSP00000398623;Parent=transcript:ENST00000445064;protein_id=ENSP00000398623 3 havana exon 33691 33750 . - . Parent=transcript:ENST00000445064;Name=ENSE00001699437;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001699437;rank=2;version=1 3 havana five_prime_UTR 33714 33750 . - . Parent=transcript:ENST00000445064 3 havana exon 34943 35492 . - . Parent=transcript:ENST00000445064;Name=ENSE00001760755;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001760755;rank=1;version=1 3 havana five_prime_UTR 34943 35492 . - . Parent=transcript:ENST00000445064 3 havana mRNA 33640 35527 . - . ID=transcript:ENST00000432213;Parent=gene:ENSG00000157020;Name=SEC13-212;biotype=protein_coding;transcript_id=ENST00000432213;transcript_support_level=4;version=1 3 havana CDS 33640 33713 . - 0 ID=CDS:ENSP00000404141;Parent=transcript:ENST00000432213;protein_id=ENSP00000404141 3 havana exon 33640 33750 . - . Parent=transcript:ENST00000432213;Name=ENSE00001723822;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001723822;rank=2;version=1 3 havana five_prime_UTR 33714 33750 . - . Parent=transcript:ENST00000432213 3 havana exon 35045 35527 . - . Parent=transcript:ENST00000432213;Name=ENSE00001602515;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001602515;rank=1;version=1 3 havana five_prime_UTR 35045 35527 . - . Parent=transcript:ENST00000432213 3 . biological_region 19376 19599 0.79 - . external_name=rank %3D 1;logic_name=firstef 3 . biological_region 34943 35287 1 - . external_name=rank %3D 1;logic_name=firstef 3 . biological_region 35257 35691 376 . . external_name=oe %3D 0.87;logic_name=cpg bcftools-1.21/test/csq/ENST00000422159/multiallelic.vcf000066400000000000000000000003071467060157400220270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 3 279 . TAGAGAG TAG,T . PASS . GT 0|1 0|2 bcftools-1.21/test/csq/ENST00000422159/short.gff000066400000000000000000000030451467060157400204740ustar00rootroot000000000000003 Ensembl chromosome -10285565 188009993 . . . ID=chromosome:3;Alias=CM000665.2,chr3,NC_000003.12 3 ensembl_havana gene 100 7381 . - . ID=gene:ENSG00000157017;Name=GHRL;biotype=protein_coding;description=ghrelin and obestatin prepropeptide [Source:HGNC Symbol%3BAcc:HGNC:18129];gene_id=ENSG00000157017;logic_name=ensembl_havana_gene_homo_sapiens;version=16 3 havana mRNA 185 4646 . - . ID=transcript:ENST00000422159;Parent=gene:ENSG00000157017;Name=GHRL-203;biotype=protein_coding;tag=basic;transcript_id=ENST00000422159;transcript_support_level=1;version=5 3 havana three_prime_UTR 185 277 . - . Parent=transcript:ENST00000422159 3 havana exon 185 328 . - . Parent=transcript:ENST00000422159;Name=ENSE00003558112;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003558112;rank=3;version=1 3 havana CDS 278 328 . - 0 ID=CDS:ENSP00000405464;Parent=transcript:ENST00000422159;protein_id=ENSP00000405464 3 havana exon 4196 4312 . - . Parent=transcript:ENST00000422159;Name=ENSE00003542562;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003542562;rank=2;version=1 3 havana CDS 4196 4312 . - 0 ID=CDS:ENSP00000405464;Parent=transcript:ENST00000422159;protein_id=ENSP00000405464 3 havana CDS 4507 4614 . - 0 ID=CDS:ENSP00000405464;Parent=transcript:ENST00000422159;protein_id=ENSP00000405464 3 havana exon 4507 4646 . - . Parent=transcript:ENST00000422159;Name=ENSE00001747893;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001747893;rank=1;version=1 3 havana five_prime_UTR 4615 4646 . - . Parent=transcript:ENST00000422159 bcftools-1.21/test/csq/ENST00000422159/test.cmd000066400000000000000000000004721467060157400203160ustar00rootroot00000000000000{bin}/bcftools csq -f ENST00000422159.fa -g ENST00000422159.gff multiallelic.vcf | {bin}/bcftools query -f'[%POS\t%REF\t%ALT\t%GT\t%TBCSQ\n]' | ../sort-csq -q echo {bin}/bcftools csq -f ENST00000422159.fa -g short.gff multiallelic.vcf | {bin}/bcftools query -f'[%POS\t%REF\t%ALT\t%GT\t%TBCSQ\n]' | ../sort-csq -q bcftools-1.21/test/csq/ENST00000422159/test.cmd.out000066400000000000000000000025561467060157400211310ustar00rootroot00000000000000279 TAGAGAG T,TAG 0|1 . 3_prime_utr|GHRL|ENST00000287656|protein_coding,3_prime_utr|GHRL|ENST00000335542|protein_coding,3_prime_utr|GHRL|ENST00000429122|protein_coding,3_prime_utr|GHRL|ENST00000430179|protein_coding,3_prime_utr|GHRL|ENST00000437422|protein_coding,3_prime_utr|GHRL|ENST00000439975|protein_coding,3_prime_utr|GHRL|ENST00000449238|protein_coding,3_prime_utr|GHRL|ENST00000457360|protein_coding,stop_lost&frameshift|GHRL|ENST00000422159|protein_coding|-|91L*>91K|279TAGAGAG>TAG,stop_lost&frameshift|GHRL|ENST00000446937|protein_coding|-|40L*>40K|279TAGAGAG>TAG 279 TAGAGAG T,TAG 0|2 . 3_prime_utr|GHRL|ENST00000287656|protein_coding,3_prime_utr|GHRL|ENST00000335542|protein_coding,3_prime_utr|GHRL|ENST00000429122|protein_coding,3_prime_utr|GHRL|ENST00000430179|protein_coding,3_prime_utr|GHRL|ENST00000437422|protein_coding,3_prime_utr|GHRL|ENST00000439975|protein_coding,3_prime_utr|GHRL|ENST00000449238|protein_coding,3_prime_utr|GHRL|ENST00000457360|protein_coding,inframe_deletion&stop_retained|GHRL|ENST00000422159|protein_coding|-|90SL*>90*|279TAGAGAG>T,inframe_deletion&stop_retained|GHRL|ENST00000446937|protein_coding|-|39SL*>39*|279TAGAGAG>T 279 TAGAGAG T,TAG 0|1 . stop_lost&frameshift|GHRL|ENST00000422159|protein_coding|-|91L*>91K|279TAGAGAG>TAG 279 TAGAGAG T,TAG 0|2 . inframe_deletion&stop_retained|GHRL|ENST00000422159|protein_coding|-|90SL*>90*|279TAGAGAG>T bcftools-1.21/test/csq/ENST00000423372/000077500000000000000000000000001467060157400166455ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000423372/ENST00000423372.fa000066400000000000000000000107351467060157400210010ustar00rootroot00000000000000>1 1:134901-139379 ACCTACCAAAACATTTACATAATGGTGGAAATATTCCAAAATTCAATATTTTGGGATTTA TACACAAAAGATAAACAAATTAGAGGCCAAGAGGCTGCCGGAAGGGAAAAACAGGGCCTG GAATGGCCGACGTGAGGAATGAGCTGGGCCTAAAGAGGCCACTGGCAGGCAGGAGCTGGA CCTGCCGAAGTGGCCGAAAGGCAGGAGCTTTGGACTGGGGAGGCCGCAGTGAGGCGAGAG CTAGCTGGGCGTGGAGAGTCCGCTGTGAGGCCGAGGCCGAGGCTGGGCCCGTGCAGGCCT TCGAGACGCAGGAGGCCGGGCCTGCAAAGGCCGACTGGAGATCAAGTTCTGCGCCTGAAG AGGCTGCCAAAAGTCAAAAGCGGGGCCTGGGAAGGCCGCCGAGAGCCATGAGCTGGGCTG GGCCGAAAGAGGCCACTGGGAGGCAGGAGGAGCTGGGCCTGGAGAGGCTGACTCGAGGAA GTTTTGCACCTGGAGAGGCCGTCGAGAGGACGGAGCTGGGCCCAGGGAGGCCGACTTGCT GCTCTTCCAGGCCCACTTCCAGGCCGACTTGAGGACGACTTGGGCCTGCAGAGGCCGCCG GGAGGCTGGAGCTAAGCCTGGAGAGACTGACTTCGGGACGATTTGGGCCTGCGGAGGCCG CCGGGAGGCCCAAGCTGGGCCTAGAGGAGCCCACCGACCGGAGGCCATTTGGGGCCTGCA GATGTCATCGGAGGGCCAGGAGCTGAGCCTGGAGAGGCCACCGCGAGGCCTGAGCTGGGC CTGGGGAGCTTGGCTTAGGGAAGTTGTGGGCCTACCAGGGCCGCTGGGAGCTGGGCAGGA GCTGAGTCCAAAGACGTTGTTGGGACCTGGAGTCGGGCCAGAGTCCGGCCTGGAGATGCA GCCGGGAGGAAGAGCTGGGCCCGGAGGGGGCGCCGGGAGGCTGCAAGTGGGTCTGAGAGG CCAACTTGAGGAGGCCTGGCCTCTGCCTCCCGCATTGCCCAGCTGTTCCTCCTGGCTGCA TCTCCCACCTCCCAGCAAACAAGCTCTTTTGGCTCAGCTCCCGCCTGCGTTTGTAGACCC CAAAGTTTCTGCAACCAAGCTCTTCAGACCCACATCCCTTCTCCCAGTGACTGAACAGTC CCAGCTCCGGCTGGAGAAGGGTGTCTGCAGACCCCGCTGTTGCCTCCCAGGGGAGTCTCC AGGCCCAGCTCTCGCCCCACCGCGACCTCCCAGGCCCAAGTCCCTGCCTACCTCCCAGCA GCCCGAGTGCGATCCTGTTCCTCCCTCACGGTGGCCTGTTGAGGCAGGGGGTCACGCTGA CCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGCTCACACTGACCTCTCTCAGCG TGGGAGGGGCCGGTGTGAGGCAAGGGGCTCACGCTGACCTCTGTCCGCGTGGGAGGGGCC GGTGTGAGGCAAGGGCTCACACTGACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCAA GGGGCTCACGCTGACCTCTGTCCGCGTGGGAGGGGCTGGTGTGAGGCAAGGGCTCAGGCT GACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTCACGCTGACCTCTGTCC GCGTGGGAGGGGCCGGTGTGAGACAAGGGGCTCACACTGACCTCTCTCAGCGTGGGAGGG GCCGGTGTGAGGCAAGGGGCTCAGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAG GCAAGGGGCTCAGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTC AGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGGGTGAGGCAAGGGCTCACACTGACCTCT CTCAGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTCGGGCTGACCTCTCTCAGCGTGGG AGGGGCCGGTGTGAGGCAAGGGGCTCGGGCTGACCTCTCTCAGCGTGGGAGGGGCCGGTG TGAGGCAAGGGGCTCGGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGG GCTCGGGCTGACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTCACGCTGA CCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGCTCACACTGACCTCTCTCAGCG TGGGAGGGGCCGGTGTGAGACAAGGGGCTCACGCTGACCTCTGTCCACGTGGGAGGGGCC GGTGTGAGGCAAGGGGCTCACACTGACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCA AGGGGCTCACGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGCTCACAC TGACCTCTCTCAGCGTGGGAGGAGCCAGTGTGAGGCAGGGGCTCACGCCTCTGGGCAGGG TGCCAGAGGCATGAGTTGGGCATCAACAGGCCACCGTGAGGGAGGAGCTGGGCCGCACGC GGGCTGCTGGGAGGCAGGCAGGGACTTGGCCCCGGGAGGCCGCCGTGGGGGCAAGAGCTG GGCCTGGAGAGGCCCCTGGGAGGCAAGGGCGGGGCCTGCAGAGGCTGTTCTCCAACCAGT GCTAGAACTGTACAGGCCACCAGGAGGCAGGAGGTGGGCCCTCAGAGCTTGGCTGGAGAA AGTTCGGGGCCTACAAAGGCGGTTGGGAGCTGGGCAGGAGTTGAGCCAAAAGAGCTTGCT TACTTGCTGGGAGGCAGGGCCGGGAGAGCCCGACTTCAGGACAACTTGGGCCTGCGGCGG TCGCCGGGAGGCCCAACCTTGGCGTGGAGGAGCCCACCGACCGGAGACCATTTGGGGCCT GGAGATGCCATCGGAGGGCAGGAGCTCATCCTGGAGAGGCCACCGTGAGGCCTGACCTGG GCCTGGGGAGCTTGGCTTGAGGAAGCTGTGGACCGACCAAGGCCGCCAGGAGATGGGTAG GCACTGAGTCCAAAGAGGTTGTTGAGAGGCAGGAATCGGGCCTGGAGACCCAACCAGGAA GAAGAGCTGGGCCCGGAGAGAACGCCCGGAGGGTGCAAGTGGGTCTGGAGAGGCCGACTT GAGGAGGTTCTGGGCCCGGAGAGGCCGCTGGAAGGGAAAAACTGGGCCTGGAAAGGCCGT TGTCAGGAATGAGCCCCATGGGCCTGAAGAGGCCACTGGCAGGCGGGAGCTGGGCCTGCC GAAGCGGCCGAGAGGCAGGAGCTTTGGACTCGGGAGGCCGCAGTGAAGCAACAGCTAGCT GGGCGTGGAGAGTCCGCTGTGAGGCAGAGGCTGGGCCTGTGCAGGCCTTCGGGAGGCAGG AGGCTGGGCCTTGTCGAGGCCTGCAGAGGCCACCGAAAGTCAAAAGCGGGGCTTGGGAAG GCCGCCGGGAGGCATGAGCTGGGCTGGGCCGAAAGAGGCCACTGGGAGGCAGGAGGAGCT GGGCCTGGAGAGGCTGCCGAAAGGCAGGAGCTTCACCTGAGGATGCCACAGTGAGACACC ATCTGGGTCTGGAGGGTCCACTGTGAGGCAGAGGCTGACCTGTAGAGTCCGACAGTAGAC AGAAGTTGGGCAAAAGCCTGATTTGAGGAAGTTTTGGGCTTCAAGAGTCAGCCACGAGGC AGGCACTAGGCCTGGAAATGGCCTCACAGTCATAAGTTGGGCCTAAATGGGCCACTGTGA GGGAGGAGCTGTGCCTGTTGAGGCTGCTGGCAGGCAGGCAGAAATTTGGCCTGGGGCAGC TGCCATGAGGCAAGAGCTGGGCCTGGAAAAAGCCCCTGGGAGGCAAGAGCAGGGCCTGCA GAGGCTGTTCTCAAGTCAAAGCTGGGCCTGTTGATGCCACCGGGAAGCAGAAGGTGGGCC TGGAGAGTTTGACTTGAGGAAGTTTTGGGCCTACATTGGCCGCCATTAGCTGGACAGGAA CTGGGCCAAAAAAGGCTGTTGTGAGGCAGCAGTTGTGCCTGTAGACCCAGCCAAGAGGAA GAGGTGGGCCTGGAGAAGCCCCCATGAGGCAGAGGTTGGGCCTGTAGACGCTGACAGGAG GCAGGAGCTGGGCCTGGACAGGTCAACTTGAGGAGATTTTGGGCCTTCATAGGCCACCAG GAGGCAGCAGTTGGGACTAGAGAGTCTGACTTGAGTAAGTTTTGGGCCCGGAGATGATGT CCTGGGACAGGAGTTGGCCGTGGAGAGGCCACCGTGAGGCATAAGCTGGATGTAGAGAGG CCAGTGTGAGGCAAGACCTGGGCCTGTCTAGGCTGCTGGGAGACAGGCAGGAATCTGGCC AGGGAAGGTTGCCATGAGACAAAAGTTGGGCCTGGAAAGGCCCTTGTGAAGCATGAGCTT GGCCTAAAGAGGCCACTGGGTGGCAGGAGCTGGGTGTGTAGAAGCTGCTGAAAGGTTGGG AGCTTGGCTTGGGGGGTCCACAGTGAGGTAGAAGCTGGGCGTGAAGAATCTGCTGTGAGG CAGACGTTGGGACTGTAGAGGCTGACGGGAGGCAGAGGC bcftools-1.21/test/csq/ENST00000423372/ENST00000423372.fa.fai000066400000000000000000000000201467060157400215210ustar00rootroot000000000000001 4479 19 60 61 bcftools-1.21/test/csq/ENST00000423372/ENST00000423372.gff000066400000000000000000000021111467060157400211420ustar00rootroot000000000000001 ensembl gene 1 4479 . - . ID=gene:ENSG00000237683;Name=AL627309.1;biotype=protein_coding;description=Uncharacterized protein [Source:UniProtKB/TrEMBL%3BAcc:R4GN28];gene_id=ENSG00000237683;logic_name=ensembl;version=5 1 ensembl transcript 1 4479 . - . ID=transcript:ENST00000423372;Parent=gene:ENSG00000237683;Name=AL627309.1-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000423372;version=3 1 ensembl exon 1 902 . - . Parent=transcript:ENST00000423372;Name=ENSE00002314092;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002314092;rank=2;version=1 1 ensembl three_prime_UTR 1 902 . - . Parent=transcript:ENST00000423372 1 ensembl three_prime_UTR 2721 3629 . - . Parent=transcript:ENST00000423372 1 ensembl exon 2721 4479 . - . Parent=transcript:ENST00000423372;Name=ENSE00002221580;constitutive=1;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002221580;rank=1;version=1 1 ensembl CDS 3630 4409 . - 0 ID=CDS:ENSP00000473460;Parent=transcript:ENST00000423372;protein_id=ENSP00000473460 1 ensembl five_prime_UTR 4410 4479 . - . Parent=transcript:ENST00000423372 bcftools-1.21/test/csq/ENST00000423372/insert3.txt000066400000000000000000000005661467060157400210040ustar00rootroot000000000000002723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA 3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA bcftools-1.21/test/csq/ENST00000423372/insert3.txt-l000066400000000000000000000005661467060157400212350ustar00rootroot000000000000002723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA 3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA bcftools-1.21/test/csq/ENST00000423372/insert3.vcf000066400000000000000000000007741467060157400207440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 2723 . G GAAA . . EXP=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:2,exon:2, spliced utr 1 3630 . T TAAA . . EXP=stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA;type=CDS:0, another stop 2aa further bcftools-1.21/test/csq/ENST00000423372/snps.txt000066400000000000000000000113471467060157400203770ustar00rootroot000000000000001 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2712 A C intron|AL627309.1||protein_coding 2712 A C intron|AL627309.1||protein_coding 2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding 2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding 2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3630 T A @3632 3630 T A @3632 3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C 3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C 3633 T A @3634 3633 T A @3634 3634 A C missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C 3634 A C missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C 3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A 3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A 3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A 3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A 4401 C A @4402 4401 C A @4402 4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C 4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C 4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C 4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C 4407 G A @4408 4407 G A @4408 4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A 4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A 4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding bcftools-1.21/test/csq/ENST00000423372/snps.txt-l000066400000000000000000000117051467060157400206260ustar00rootroot000000000000001 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2712 A C intron|AL627309.1||protein_coding 2712 A C intron|AL627309.1||protein_coding 2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding 2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding 2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding 2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding 3630 T A @3632 3630 T A stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260C|3630T>A 3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C 3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3632A>C 3633 T A @3634 3633 T A missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259F|3633T>A 3634 A C missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C 3634 A C stop_gained|AL627309.1|ENST00000423372|protein_coding|-|259L>259*|3634A>C 3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A 3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A 3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A 3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A 4401 C A @4402 4401 C A synonymous|AL627309.1|ENST00000423372|protein_coding|-|3L|4401C>A 4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C 4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4402A>C 4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C 4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C 4407 G A @4408 4407 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|1T|4407G>A 4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A 4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4408G>A 4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding 4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding bcftools-1.21/test/csq/ENST00000423372/snps.vcf000066400000000000000000000113131467060157400203270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:0,transcript:0,exon:0,three_prime_UTR:0 1 3 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:2,transcript:2,exon:2,three_prime_UTR:2 1 4 . T A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:3,transcript:3,exon:3,three_prime_UTR:3 1 5 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:4,transcript:4,exon:4,three_prime_UTR:4 1 9 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:8,transcript:8,exon:8,three_prime_UTR:8 1 10 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:9,transcript:9,exon:9,three_prime_UTR:9 1 2712 . A C . . EXP=intron|AL627309.1||protein_coding;type=three_prime_UTR:-9,exon:-9 1 2713 . G A . . EXP=splice_region|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-8,exon:-8 1 2717 . G A . . EXP=splice_region|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-4,exon:-4 1 2718 . G A . . EXP=splice_region|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-3,exon:-3 1 2719 . G A . . EXP=splice_donor|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-2,exon:-2 1 2721 . C A . . EXP=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:0,exon:0 1 2723 . G A . . EXP=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:2,exon:2 1 2724 . G A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:3,exon:3 1 2725 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:4,exon:4 1 2729 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:8,exon:8 1 2730 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:9,exon:9 1 3621 . G A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-9 1 3622 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-8 1 3626 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-4 1 3627 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-3 1 3628 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-2 1 3630 . T A . . EXP=@3632;EXPL=stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260C|3630T>A;type=CDS:0 1 3632 . A C . . EXP=stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C;EXPL=stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3632A>C;type=CDS:2 1 3633 . T A . . EXP=@3634;EXPL=missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259F|3633T>A;type=CDS:3 1 3634 . A C . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C;EXPL=stop_gained|AL627309.1|ENST00000423372|protein_coding|-|259L>259*|3634A>C;type=CDS:4 1 3638 . T A . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A;type=CDS:8 1 3639 . G A . . EXP=synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A;type=CDS:9 1 4401 . C A . . EXP=@4402;EXPL=synonymous|AL627309.1|ENST00000423372|protein_coding|-|3L|4401C>A;type=five_prime_UTR:-9 1 4402 . A C . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C;EXPL=missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4402A>C;type=five_prime_UTR:-8 1 4406 . A C . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C;type=five_prime_UTR:-4 1 4407 . G A . . EXP=@4408;EXPL=synonymous|AL627309.1|ENST00000423372|protein_coding|-|1T|4407G>A;type=five_prime_UTR:-3 1 4408 . G A . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A;EXPL=missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4408G>A;type=five_prime_UTR:-2-incomplete 5'cds,not a start 1 4410 . A C . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:0 1 4412 . A C . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:2 1 4413 . A C . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:3 1 4414 . G A . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:4 1 4418 . G A . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:8 1 4419 . G A . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:9 bcftools-1.21/test/csq/ENST00000436063/000077500000000000000000000000001467060157400166465ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000436063/ENST00000436063.fa000066400000000000000000000301201467060157400207710ustar00rootroot00000000000000>1 1:94333353-94345494 TATTCCAGAAACAAAAGTAGTTTTTTTTTAAAATAAAAGAGAACAGACATAGATGCTTCC CTAACTCCAACTATGAATGTTATTGTCAGTTCTGCTATTACTAGCTTTTGACTCCAAGCA GTAAATATGAGATTTTGGACATAGGTATGGGCAGACTGCATGACTAAAACACCAAAAGCA ATGGCAACAAAAGGCAAAATTGACAAGTGGGATCTAATTAAACTAAAGAGTTTCTGCACA GCAAAAGAAACTATTATCAGAGTGCACAGGCAATCTACAGAATGGGAGAAAATTTCTGTA ATCTATCCATCTGACAAAGGGCTAATATCCAGAATCTACAAAGAACTTAAACAAATTTAC AAGAAAAAACCCCATCAAAAAGTGGGTGAAGGATATGAACAGACACTTCTCAAAAGAAGA CATTTATGCAGCCAACAAACATGAAAAAACGCTCATTATCACTGCTCATTAGAGAAATGC AAATCAAAACCACAATGAGATACCATCTCATTGCCAGTTAGAATGGCAATCATTAAAAAG TCAGGAAACAACAGATGCTGGAGAGGATATGGAGAACTAGGAACACTTTTACACTGTTGG TGGGAGTGTAAACTAGTTCAACCATTGTGGAAGACAGTGTGGTGATTCCGCAAGGATCTA GGACCAGAAATACCATTTGACCCAGCAATCCCATTACTGGGTATATACCCAAAGGATTAT AAATCATTCTACTATAAAGACACATACACAAGTATGTTTACTGTGGCACTGTTCACAATA GAAAAGACTTGGAACCAACCCAAATGCCCATGAATGATAGACTGGATAAAGAAAATGTGG CACATATACACCATGGAATACTATGTGGCCATAAAAAAGCATGAGTTCATGTCCTTTGCA GGGACATGGCTGAAGCTGGAAATCATCTCAGCAAGAACAGAAAACTAACACAAGAACAGA AAACCAAACACTGCATGTTCTTACTCGTAAGTGGGAGGTAAACAATGAGAACACATGGAC ACAGGGAGGGGAACATCACACACTGGGGCCTGTTGTGGGTGGGGGACTAGGGGAGGGATA GCACTAGGAGAAATACCTAATGTAGATAGGTTGATGGGTGCAGCAAACCACCATGGCACG TGTATACCTATGTAACCTGCATGTTCTACACATGTACCCCAAAACTATTATTAAAAAAAA AAAAGATTTCATATTTGCTGATATCTCAAGGAAGCAGTATGCTGGAAAAATAGAGGTAAA GTGAATAGTAACATAAAGGAAGCTACAACTCACCAAGTATCAACAGAAATGACCAACACT CCTTGGGTGCCAGAAACCAGCTTAGCCAGGGTGCATACTGTACCACTGGAGAAGAGGTAA GCTGGGTTAACTTCGAAGAAACCCTGGCCAACTTAAATTATAGTTTAATCCTGTTTTACT TGGACCACAACACTTAAATCTAGATAAAAACCAATTATTCCTCCCTGTTTCAGTTGCCAA GCAAGGAAAACAGCTCCTCTGCCCAAGCTTTCTAGGTCATATTCTTCATATCTTTGTATC CCAACTTTCTGGATCTGAATTTTATAGCTAACTATAGGGCATTGCCTCTCTACCATCTCC CGTCCCCTACACAGACACACACACACATACACACATAAAACTACCTATTAATTACAATAA TGTTTATATATCTTTGATCATTTTTTAAAGTTCTTTGAACATGTTAGCAAACTTTATACT TCCTATCTTTTAATTAAATTTTCTTTAAATAACTAAGCATTGAAAACTTTACAAACCATC AGTTATCTTAAAATGGTTGAGATTTTTTTTCCTTTTTTCCCATAAAGAGTCTACACCAGG GTGGGTCTTTTAGACACCCCTATTTTCTAAGGGCATGTAATCGATTCTCAAATCAACTTT TTCCAAATACAAATTCCTGTATGAACAGGGCCAGTCTATGGTAAATTAATTTAGATGATG GTGTTAGTTTTCCAAACGTCTTTAATAAGTAAATAAAGGAGCAATGTAAAATGTTGCAGT TTGCTTGGTAAATCTTAATTGCGAAATTTCTTCTTCTTTCGGAACTTTTTTCCTGCTGCA TTTGCTGCTTTTTCAGCCATGATCTCTGAGTACTTCCTTCGGTTGTATCTGAAAAAGAAA AATCAGAACTTTATGTTTGATATATCAGACATTAGAAGTTAATATAACCTTAGGGTAAAA GTTGGGAATGGAGTGGTGGACAAGACAAGTATAGTCTCTGACCTCATAGCACTTGCTTGC AATCTAGGGAGAAAAAATGGCAACTGTAGTAGGAAGACTTTCCTACTATATGCACTATAT CCATCTATCTATCCATATATCCATATATGATCTATATATGCACTATATCCATCCACCAGG CTGTATCAAATGCTTTAAACATTTTTGAGGGATAAAAACACAAAAATCAGGACTAAGCAA AACAAAAAGTCACACTTATCCTGAAAATGCACAGTATGATATATATATTTCTTAGAAGCG ACCAATGGTTTTCAAAGTGTGGTCTGTGGAGTAGACCCTTTCAAGGGATTCATTAGGTAA AAACTATTTTCTCAAGAATACTAAGGCATTAATCGCTTTTTTCACCCTCGTTCTCTCATG AGTGTAGTGTTTTCCAGGGGCTACGTGATGTATGTTATCTGCAGAAGCAGGTATGAGCCT CTGTCTTTAGTTAAGCCAGACATTAAAGAGATTTGCACTAAATTATTTTTCATAAAAATA TATATTCATGTTAATATGTTATGGGTTATTATAAATGAGTTATTTTTAAATTATTTGAAA ATTTATAAGTTTATACATTTTTAAAGCAAAGTATACATATTATAAAATAAATATGAATTC CTTTACCTTCTGAATTCAGAATCAGCCAGCAGTTCTTCCACAATAGTTCTTTTCCTTTGC TTCTTGGGAATTCGTGAATGGTAGAAATCAGCTGGATTGTCAACAATGGTTCCAATCTGT GAACAATTGATTGAAATAAGTCATGCATTGAGTGCCAAGATGCTTTCATACTTCAGTGTA GCTCTAATTATATTTAGAGAAAGGAATGGAAAGAACAAGCTTACATTACACTAATAGTAA TGTAAATTTTGCCATTTATTTAAAGCAAAAAAAAAAAAGTAGCATAGTGGTGCTATTATG TTTCTTCAGTAGTTTATAGTAGATCCAAAATTTCTTTGCTAAACACTAAATTCATGATGC ACAGTGTAACTAAAGGAGAAAAGTGGAACAGATAATATATACTTTTTGTTCTAGTTTCCC AAATCAATGAATTAGACACATAAATTCTACTACATACCTATTTGGTTTCCTAGGTCATCA CAAAGGCTGCCAGTTTGGCCTACTTAGTGATCATTCTGTATTTGTTCATACACTCAACTG AATAAAATTTACAGTGATCACTATGCACCAGGCACTGTGTTACATGTTAGGGAAACAAAG AACATCTGGTTCCTGCAGTGCAGAGCCTGCAGTCTTAAGGAAGCTCCACAAAAAGTAACT AAAATATTAAAGCATAACATGTGCTGAACAAAACACTATAGACGCTCTGAAGACAAAGTG ACCAATTGTACCTAAGAGAGGTAAGGAAGATTTAACAAAGAATGACAATTTAGCTTGAAT TTGTATGGGTAAAATTTCACCAAACAAACAAGAACTATGGATATGCAAAGTCAAATTATG CAGGGACTGGTATGTACGTGTTCTGACAAGACTGAGTAGCTAAGTGTGTTGGAATTTGTT GGGCTATATGATGAAAGGCAGGTGAACTAGTTTGGGTATGGATTATTAATGGCTAAATGA AAGGATACAGACCCAATCCTATGTCATAATTCATCACTGAATGTTTCTGAGCAGAGGTGT AACACGAACAGATGAAAACATTTTAAAAACCAACTTGGATTAGTACACGTGATACCCTTT TACCCCTATCCCGTATGGACTCTTGCTGTTAGGCTGATACTATTCATACATTCACATAGT GAACTTTATAGGTTCAACAGGTTTTAGCTGACCTGGAAACCATTTGTAACACCATCTCTC TAAATGTGATCAAATTAAAAGTTAGTGGCTGAATTGGGTAATGGCCATTCTTATATGGCC TATGCAGATATGTTCCATACATTAGGCATGCACAATGGAAATATCCTCTATTTTAGGAGT AAACTTTAAAGAACACTACAGTGCTTTCCAAACTAAAATTCACAGATCATCACCACTATT CTGTTTGCTTCATACCTGGAAGTACTTGGGGAAGCCATCTCTATCATTTTTCTTGTAAAA TCTTTTCGGGTCCATGCTGGCTCTCATCTTCAGTGCTTTGAGATCATTTTTCAGTTCATT TGTCATTTCTGGAGCTTTCATACCAAACCAGCCATCCCCTGCTGTTTTTTGTCGTTCTTT CTGAAATTATGATTTCAAAAATAAACATTCTAACAGCTAAGAGTATACATTATAATTCAT TTCCCCTGAAGTAACACATACAGAAAATTTTGTAAATTAAAAACAAATGGTTACTTTATT GAAAGCACTTAAATCCAGAATCATAGAGATAAAAGGAATTAAATCACAAAAAGTGACTTC TCCGCTAAATTAGGGACAGGATTATCAGTTTCATAAATGAGGGCTCCGTAAAATCTATTT TCTGTCTCAGAGAGTAACTGCTGACTTGCTGGGAGAATAACACACAACTTCAATTTTTAT TGTCTAAAACAGACTATATGCAGTAAGAAAATGTATAAAAACACTTTCGTTTCTAGAGCT TATATGTAAACATTTTTATTCAGTCACCCAGGAGTCTCAGAATGCCACTCATACAAGGAT CCAGAACCTTGTGTTATTTCTACAATAAAACAAAATACTATTCTTTAGAAAACTCCTACA AGTTATTTAATTTTGTTTCATTCATACAACAAGTATTTAGTTAGTGCCTACCATGTGCCA GGGTGCTCCATATTACAGTAACATTACTAGAATACCATCCTCAACTTTCCTTCAAGCTCT CTGGATAACTAGTCGAAATGGCAGATAGAAGTAATCTATATATATATATATTTTTTTAAA AAACCTCTACTTATAGATGCACTATTGTGGCTGCAAAGATGTGAAAATCTATACATAATG TGTTTATGGTACTATATTTTACAGCCCTTAGAAATCTGTAATTATTTTCTTTGGACTCAT ATATAGACCAACAGATACAGTTTAATTGTGCAGTTATGTTGTATAAGCTGAAAATATATA GCCAAACATATCTAAGCATTTTAATTAAGTCACTGTACTTACTCTGCGTTTTTTCTGAAG TTGATACTTTGATTCACTATATGGTGGAACACAGTGGTTTTTTTCAAAATCAGGTGTAAT GACGGCTTTCTGCAGAAGCTATAAAAACATAAAATTGGTTTTAAAATAATGTCAGAATGT TATATAAGTTTTTCAACAGTTTAAACTTCTGTAAGTTTTAAAATTTTTAGTCAGCCTGGC AAAGTGGCTCACACCTATAATCCTAGTGCTTTGAGGAGGCCAAGGGAGGAGGATCACTTG AGGCCAGGAGTTTTAGACCACCTTGGTCAACATAGCAAGACCCTGACTGTAAAAAAAAAA AAAAAAAGAAAAGAAATTAGTTGGGCATGGTGGCACACACCTGTAGTCCCAGCTACTCAG GACGCTAAGGCAGAAGGATCACTTGAGGCCAGGAGCTTGAGGCTGCAGCAAGCTATGACT GTGCCACTCACTCCAGCCTGGGTGACAGAGTGAGACCCTGTCTCCCCCCAAACCCAGCTC CCTCCCAAAAAAAAAAAGAAAAAAGAAAAAAAAGGCCAGGCACGATGGCTCATGCCTATA ATCCCAACTCTTTAGGAGGCCAAGGCAGGACAATCACTTGAGGCCAGGAGTTCAAGACTA GCCTGGGTAACATAAGAAAACGCCATTTCTCCAAAATAAATAAATAAATTTGTGCAGTCA AATCTGTTTATCTTTTCCTAAATGATTTCTGTACTTTTGTTACTTGACTAGGATGATTAT ATTCTCCTAAAACTCTGTGTGACTAAAGGAACCTCAGGTTAATTAGTATTTTTCTCAGTA CAAGAACCAAGTAAGACTGCTCTGTAGCCCTCAAAATAGTTTACAGGAATATAGTACAAG CATTAATTTGGGACTGACATTTGAAATGATCAACTCAGAAATTAACAGTCAGGCACACAA TTCAGGTTCAGGCCTAGATGTTTCTGTGTGGTATAGGTAGCCGTCTAGGCTTTCCTATCA CTCATAAAAGGGGGCATGATATTTACTTAACAAATGATTAAGAGTTTGCTGTGAGTCAAG TACTGTAGTACATTCAAGGACAGTGGTTCTCAACTGGGAGCATCTGGCAATGTCTGGAGA CATTTTTGGTGGTGGTGAGGATAAGGAAGAATGCTACTGACATCTAGTGGGCAAAAGATA GGGATGCTGTTAAACATCCTACTATGCACGGAACATCTCACAACAAAATTATGCAGCCCA AAACATCAGTAGTGCTGAGACTGAAAAACCCTGTTTTAGGAATATAAAGAAAAGATGGTA AGTTAATATATCACATGATCAACAATGAATCAGATCTATGCTAGATGTTATGGAAACAGA GGGGTTGTGAGAAGGACTGGAGGTAAAATATTCCCCAAGGGCAACGATCAATTATTTTGC ACTTGCTTGGGGAAAAGCAGGGTAAGTTCAGGCAACTACAGTAGTCTTCAGTGGCAAGAA TAGAGCAGATGACAGCTGGGTGGGGTAGAGAGGTACTTTGAAGGATTCAAGAGAATACTG TCACATCTGTGTGTGTGGTGTGTTTTTTGGGGCAGGGAGGAGAGATGTGGTCTAGCTATG TTGCCCAGGTTGGTCTCAAACTCCTGGGCTTAAACAATTCTCCTGCCTCAGCCTCCCAAA GTGCTGGGATTATAGATGTGAGCTACCTTGCCCAGCCGGATTTGTGTTTTTAGACAGAGA AATCTAGAAGTGTGGAGGATGGCTTGAAGAACAAGATGAAAACAAGATCAATAAGGAAGC CACTGGAGTAGTCCAGATGAGAAGCAAAGGCCTGCACTAGCTGGTGACAGTCGCTTGAAA AGGAGGAAGCAGAGAAATATCTTCCCCTAGAGGCTTGGTGACTGACTACAAAAGGAAAAG AGAGTTTGGTTTCATTAGCCAGAAAAAAGAATACAAGAAGAGGATTCCTGGTTCAGGCAG GGAAAGGGGAATTAGTGACGTCAAGTACCTGAGGACATCTAAATGAACAAATAGGTACTT GGATTTAAAGGTCTGAAAGTGACAGTGAGAAGCATCAAGGCTAGAAAATATAGATTTAGG AGAAAACAGTGCAAGGTGTTGGCTAAAGCTAAGGGTTTGGGTAAAGTTACCTTAACAGTA ATTCCTTCTGAAATTATATGTAAAATGTCTATATGCACATGTGCATTTTTTTCCGGGTGG AAGAGGCAGGCAGGCATTCACAGCTTTCAGATTCTCAACAGTCTACACTAGTTAAGAACT TAAGAACTAAAAGTATAGCAAGAAAAGGGAAAAAAACAAAACCCCTGGGATCATAATTGG TGGGTGTAAGATGAGGAACACTGACCCTGTATTGATTTATTTTTAAAGCATTATCATTCA TAGATAGGATTTTATTGTAAAAAGAAATGACTGTTTTAGAGAGAAGGAAAAAACTAACAC ATTAGGCCAATGTGGTTTCACTGTAGGAAAATTAAGTCTTTTACCAAGGACTAATTTCTA AAAGTGATTGGTTAGTTCTGTGAAAACCTAACAGCACAATTAACTTACCTCATTTTTCTT TTTCTCCTTGATCTGTGTTAGGGTTCTCTTGTTAGACTGTAGTTTATCTGCATTAAAATT AATATACAAACCACCCAACTGCTTGATACTCAGACCAGGGTCTATGCTGCTGCTTGTCAA CTTCAGACTGAAAAAGAAATCATCACTTAAAGATCAAGTAATTAAATCAAAATGGAAACA TATAAGATGGCATTTTAAAAAATCACTTATTCTTCTCTTCCCTTGTATTGTCCACAATAA AGAAAAAAAAGCATCTTATTTTTATGAGGAATTCCTGAAAAAAAACTCTAAATAAATATA TTTTTCATCATTTTATTTTATTTTTTGAGACAGGGTCTCACTGTTGGCCCAGGATGGAGT GCAGTAGTGACCACTGCAGCCTTGAACTCTTGGGACTCAAGTGATCCTCCTACCTCAACC TCCCTGGGTGGCTGGGACTACAGGTGCACACCCAACACCTGGCTCCATAATGTCAAATGA ATGAGCCATTCCATGAAGAACCCAAGGCAGTGATTTTCTCATTCCCCAGGCTAACATTTC ATATTTTTATGGTAAATTAACCACTTGAAATACATGTATCAAAAACTTATAAAAATAAAG GAAAAACTTACAGTTTAGCCTTTGTGCTATTTAGGAAGTCTTCTTCATCACTAAACTCAT CTTCATTTTCGTCATGGTCTGATGAATCTTCTTCACTTTTTTCATCCTCTTCCTCTTCTT TTTCTTCCTCAATGGCAACCTCACTTGCCTTGTCTTCCTCTTCCAAGTAAAAATTTTTAT CAGCACTCATTCCAGGAGTTGTGTCAATTACAAACAATGCATTGTCACATGACAGACTTC CTGTGTCTCCACTTAATGACTCCCTTTGGCCACTATTTTCAACAAAACATAAAGTATCCT CTTCATTCTCACTGTTTTCAGACTGTTGGCTTTCATCACTGCTGAGAACTAGTAAGACAG AATTATCTTTACCCTGAGATGTGTTGGGCGCAGACGTGTATAGTTTGGTATCACATTCAA AATCTACATTCCCTTCACTGTTCATGTCTTCACTGACACTTATAACTGTGGACTCTTCTT CATCATCACTACCACCACAATCACCAAACTTTGTCAAGTCACTTGCTTTTATGGGGCTCT TTTTGTTGTTATTCCATCTGCCTACTTCCACAGTTGCAAATGTTTGAGTTAATGATTTCA TTACAGCCTCAGAGTTCAGATTAGAGTGCACTGATACAGCATTTTTATTTTGGGGGGTTG AATGTCTCTGAGAAACTAACTGTTGAAGGCTAGTGTCCTGAAGTTCAGAAAGATTCTTCA GCTGAGAACTTTTCTCATTAATTTCTTTCCCCTCATCTGTTATTCCATTGGCATCTTCAT CCAAATCCTTACAATTCTGTTTTGTTTCTTTAAGAGATTCAACATTGGCCTGTTCGTGCA CTGTTAATATATTTTCTGAACTTCTGTGGGAGAAATCATCATCAAAGTCATTATTATAGA AATTTGGCTTATTTATCTCAGAAAGAGATCTTGCTTGTAAATGGGAAGTTTGTCTGGTAT CTGAATCCTCTGAATTCACAGGTGTACCCACGATCTGTTTCTCATTTCCTGGTACAATCT TACTATCTTTCTTTTCAGTTTGTGCCTTTAATTTCCTCTGCATACTCCTGGTTCTTCTAG TTGCAATTCCAGAGAATGAAATGTCTGAGCTTGATGTCTCAGCATCAGATATAGCTTCTG TATGAGATTCTTGGCTTGGATCTGTCAGAGATTTAGCCTTACTTCTTCTGGCTCCTGTAG TTTTTTCTGTAGGAAGCACAATTCTAGAAATACCTGAAACATGAGATTCTGCTTCAGACA CTATTTCTTCAGTGTAAGACTCCTTTGTTGGAGTTACTTTCGGCTTTTTCCTAACACTGG ACACTGGGGAGCATGCAATTAAGATCTGCCTTCTCCTAGTTACCCTTAAAATGGTATCAT GGTGCTCAGACACAGAATAATTTGACTCTGCCTCAGAGGTTTCTCCATCCGTAGATGGTT CAGTCCCCTTTGGTAGTGAGCCTGTAGTTCTGCTCTTCCTCTTTCTAGCTTTAGGAGTTC TAGGGATTAAACTTTGCTTCCCAGTGGTCTGTGATTCAGCAGTAGTTCGGGCATCAGATC CAGTACTACTTTCTGGATGCGCTTGAATCCCATTAGCAGCAAAACTCTGCAAACCAGAGA AAACACACTGTAATTTAGGTAGGGCTGGAACAAGGGCAAAGCAAATGAAATACTGACCCC AAAAGCTAAAACCCAGTAAACAAGATTACCTTTAAAACAAAAAACAAAAAAACCTGCCCA ACTCATGATTTTTAAAAAATCAAAATTTGGCCGGGCGCGGTGGCTTACGGCTGTAATCCC AGCACTCTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTTCGAGACAGCTTGGCC AACATAGTGAAACCCCATCTCTACTCAAAGTAAAAAAATTAGCGGGGCGTGTTGGTGCGC ACCTGTAATCCCAACTACTCAGGAGCCTGAGGCAGAAGAATTGTTGGAATCCGGGAGGCA GAAGTTGCAGTGAGCCGAGGCTGCGCCACTGCACTCTAGCCTGGGCGACAGAGCAAGACT CCGAATCAAAAACAAACAAACAAAAAAATCAAAATTTAAACACTGGAGCCAACCCTGCAT TTACTTCACTAGCCTCATCCTTCCTAGATGTAACTTCAGAAGCAGAACGATTAAAATTTT TCTGTTTAAAGTCAAATATAATGGGTAGACCAACATTCTGACCCACCTATAGAAGAGGGG AGAAAGGGAATATTAACTCTGAACACCGATGTGTTTAGGAACACACTGATGGAATCAGTC GCCGCCCTTACCTTTACGTACAGGAAAAAATCGCCGCCGCTCCGTTCCCTGCATCGCTGA GTCAGAATGAGACAGCCGACTAACGCCACTAAGAGTCACCAGGCGACGACACCACAGCCC TCCTCACGCCTTAAGGAGGTGATGCTGGACAGCTGCCAGCCTCCCCACGTGAAAACGAAG CTTTTTTTCCAGCCCCCCTAAATGGGGCTTGTGCATGGTGGCCGAAATTAACCCTCCTTG GTACCGTGTTAACAGTAAGGTTTAAAAGTTCGAACTGTGCTTCTGCATTAAGGAGTTGAA CGACCCAAATAAAGTTATCTAACCTCTCTTCCATACTAAAAATTGCCTTAAGAGACAGTG GTGAAGGCTAAACAGTTTCCGTGACAGGCTTAGCACGGGGCCTGGGAGACCCAAGCGCGC GGCAAGCTCGGGTCCTCTCTGTCGGCAGGTCCTCACCCTTAACCGGACCCTTGCGCCGCC CCGCCTGCCTGAGCGCGGCTCTGCGAAGCGGCGAGAAGTAGGGAAGACTGGATTTCCTAC CTTTTGCCCGGAACTTTCAGCCGACGCGGCTTGGATGCTGGCCTTAGCCCGTGCAGATCT GGTAACCACCATCTTTCCGGCTCCCTCGCGACCACCACGACTTCCCTCTTCCCTGGCGCT CCGGAAATGCGTCAGAGAACTGCCTCGAGCGCGTTTTCCGCGCAGATCCGAGAATTCGCG AGAATCTCCGCCCAGCCAGTTCAGGCCAGGGCGGTCAGAGACAAAGGGCCTGGGTTTAAG TGTGCATTTCAGAGCTGTAGAAGGCAAGCCAGATTTTTGCTGGGAAAGACCTTCATCGGG GCGGCGAAGCCCGCAGTGACAGAGGGTCTTAGCGTACCCGTTCACATGAATTGTAAAAAC GCACTTACATGCCATTCGTTCTTTCATTTGTTTAGTAGAATCGTTTGAACCCGGGAGGCG TTCTTTCATTTCTACGTTCTAAAGAGCTTAATGTAGCCATTGGTATGTCCAAGGGAGAAG TTTGAGATATTTGTGCTTTTTAAAGAAAGACAATATTTACTCGTGTATTGTGACGCTAAC TATAAATAAAATTTAAGGACTTGGTTGGGGTAAAAGGGATATAAGGTGCTCGCAGGAACT GGGAGACGAAGTGGAAAGCTGTATAATCTAAACGTGAGATGGTGTTTAGGGATTGGGAAT AGCAGAAAAGAAAAAAACGTTAAAGAAATTGTAAAGGAGAAGAATAAGGTTTTGTTGTTG TTGTTGTTGTTGTTATTGTCACAGTGAAAGGAAGAGTATGACCAGAATCAAGAGGTTTCT TTGGTTATCTTTTGAGATAAAAGGTAGAGAACTATGTTTGAGGGGATGGGAAGGGGTTGA AAAAATAAGTAAACGCAAATTA bcftools-1.21/test/csq/ENST00000436063/ENST00000436063.fa.fai000066400000000000000000000000211467060157400215240ustar00rootroot000000000000001 12142 23 60 61 bcftools-1.21/test/csq/ENST00000436063/ENST00000436063.gff000066400000000000000000000054411467060157400211550ustar00rootroot000000000000001 ensembl_havana gene 21 12122 . - . ID=gene:ENSG00000067334;Name=DNTTIP2;biotype=protein_coding;description=deoxynucleotidyltransferase%2C terminal%2C interacting protein 2 [Source:HGNC Symbol%3BAcc:24013];gene_id=ENSG00000067334;logic_name=ensembl_havana_gene;version=9 1 ensembl_havana transcript 21 11410 . - . ID=transcript:ENST00000436063;Parent=gene:ENSG00000067334;Name=DNTTIP2-001;biotype=protein_coding;ccdsid=CCDS44174.1;havana_transcript=OTTHUMT00000028317;havana_version=2;tag=basic;transcript_id=ENST00000436063;version=2 1 ensembl_havana three_prime_UTR 21 2054 . - . Parent=transcript:ENST00000436063 1 ensembl_havana exon 21 2148 . - . Parent=transcript:ENST00000436063;Name=ENSE00001774432;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001774432;rank=7;version=2 1 ensembl_havana CDS 2055 2148 . - 1 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana exon 2887 2996 . - . Parent=transcript:ENST00000436063;Name=ENSE00003641262;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003641262;rank=6;version=1 1 ensembl_havana CDS 2887 2996 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana exon 4276 4440 . - . Parent=transcript:ENST00000436063;Name=ENSE00003655393;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003655393;rank=5;version=1 1 ensembl_havana CDS 4276 4440 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana exon 5323 5418 . - . Parent=transcript:ENST00000436063;Name=ENSE00003551497;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003551497;rank=4;version=1 1 ensembl_havana CDS 5323 5418 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana exon 7849 7987 . - . Parent=transcript:ENST00000436063;Name=ENSE00000777089;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00000777089;rank=3;version=1 1 ensembl_havana CDS 7849 7987 . - 1 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana exon 8472 10066 . - . Parent=transcript:ENST00000436063;Name=ENSE00003464563;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003464563;rank=2;version=1 1 ensembl_havana CDS 8472 10066 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana CDS 11281 11352 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 1 ensembl_havana exon 11281 11410 . - . Parent=transcript:ENST00000436063;Name=ENSE00002201976;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00002201976;rank=1;version=1 1 ensembl_havana five_prime_UTR 11353 11410 . - . Parent=transcript:ENST00000436063 bcftools-1.21/test/csq/ENST00000436063/insert-before-utr.txt000066400000000000000000000000271467060157400227620ustar00rootroot0000000000000020 G GTT . 20 G GTT . bcftools-1.21/test/csq/ENST00000436063/insert-before-utr.vcf000066400000000000000000000006211467060157400227210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 20 . G GTT . . EXP=.;type=ENST00000436063:94333372-G-GTT,just before the gene/exon/utr start bcftools-1.21/test/csq/ENST00000448695/000077500000000000000000000000001467060157400166645ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000448695/ENST00000448695.fa000066400000000000000000004550421467060157400210430ustar00rootroot00000000000000>16 16:19566542-19718135 CCAAACAGCGTATTAGCCGCAAAACCAGGTACTGGCTGAACCTCAGTTTGCGTCTTCGCT CCGCCGCCTTCTGGAGTCCTTTCTGCCCCTAGAGGACGCAGGTGAGCTAAGCAGCAGTCA TGCCCTTTACCATCATGACGCCCGCAGGCGGGACCACCCGGCACTGTAGACAGCTGCCCT TTACAATCATGACTCATAGAAACTACGGCACTCTGGCCGTGGCCGACGTTGCTCCTCCGA AGCATGGCGCCGGCGGGAGTTGTAACCCGGGCTGTCCGGAGCGGGGAGCTGCCCCTCACA AGCATGGCGTCAGCTGAAAATGAAGCCTGTGCTGTGCGGAGCGTCGCCTGCCCCTCACAA GCATGGCGTCTGCAGAAGGTGCTGTGCGGCCGCTGCGGGGCGGCCAGCTGCCCTTCACAA ACATGGCGGCCGAGGGGTGCGGGGAGTGGCGGGGTAAGGATGGGAAGCCGAGCAGACGGC CCCAGAACAAGCGGTCATGTGACTGGGAAGATGGCCGTCTTTCCTTGGTAAGGAAGCAGC GGCGGGTGGGCTTTGGAGAGGGGCTGTCCTTACTTGTGATGGGGTCGGCCTGGGTCTGAG AGTGTGAATTCCTCTCTGTCGGGTTCTGGTGGTCGACCGGCCACCCCCAAGTTGTCTTGA CCGTAGAATCCCTGGCCGCTACCGCGGTCCAGCGGAGCAATCTGAAGCCAGACTGGCGGG TTCTTGGTTCTCTCCCCGTCTGCTGCCTCTCTGCGCCTTCCACGGGCCCCTGTCCATTCA TTCCCTAAAGAAAACTTGAGTTTCCAGGCTTCCGCGTCCCCAGAAGTTGGCGCGGGTTCT GGGGTCGCTGGATGAGGGTAATGGTGGACTCAGCTTTTAAAGTCTGGACGAGTCGGGAGA TCTGGCTGTTGGTCAGTTTCCTCAGCTCCTCTGTTCACCTGGAGACTTGCTTTTCTCATC TGTAAAATGGCCGCCATTCATCCTATCCTAGGCACAGCCCTCAGACTTATTCCTTGGCCT CAAGGAGCTGACAGTATAATGGGGCAGACGCACAGTAGAGGGATGTCTAAAGAAGGCATT CGGATGAGGCACCAAGAAGGGAGTGATTATCCCCACCAGGGGGCTAGGGGAAGGCTTCAG AGAGGAGGAGTTAAATTGGGTCTTGGAGGATGAATAGGAGTCCACCATAGGGAGGGCGTG GCGTGTGCCTGGTTGGCAGGCCCGTAGGTCCCTTGTGGTTGGAGTAGCTAGGAATGAGTG ACTGAAGCTTCAGGGTTCAGCAGGTGGTATGTGTGTGAGTGAAGAACTTGAGGAAGTTGT GTTGTTGATGATAGTGGGATTTGGGGACGGGGAATCTCTCCTGCATCTCAGAAAGCGAGA TAATTTACTTTCTCTTCAAATGATGTGAAGTAGCTTAGATTAAATGAGCAAATGAAAGAC CTTAGAAATAATCAGGTACAACCTTCTGCTTTTGAGCTTGATAAACACTTCATTTTGTCT TATTCCTTTCATTTGCCCAACACTTAAGAGACTGCTTCCTTGACACGCTACATCAGCATT GAATGCCTCTGAGCACTTCCACACCCTGAGGTTTTTTTTTTTTTTTCAGTTAATAGTCAT GCTGGCTGGGTATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCTGGC GGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGGCGAAACCTAATCTCT ACTAAAAATACAAAAATTAGCTGGGCTAAATTAGTGGTGGCACGCACCTGTAATCCCAGC TACTTGGGAGGGTGAGGCAGGAGAGTCGCTTGAACCTGGGAGGCGGAAGCTGGAGTGAAC CGAGATCATGCCACTGCACTCCAGCCTGGGCAACAGTGAGACTCTGTCTCAAAAAAATAA TAATAAAAAATGAAAAAGTCATGCTGGCTTGACCAAAAAGCTAACCAAAAACATGAGAAA CATTTGACTTCAGTGGATTTATCTGAAGTTTGCAATCAGAAAATCCAGGAAGATGCTGTC TTAATCTCTGCATCCCAGTACATTTCTACCTTTGGAATTTTAATTTTATATTACAAGCAG GCAAACAGGTGCCATAACGCTTTTAGTATTTAGGGTCTCTATAGTTCCTAATATGGCCGT GCTCTAAATATTTTGTTGTTGTTGTTTTTGTTGAGACGGAGTCTCGCCCAGGCTTGATTG CAGTGGCGTGATCTTGGCTCACCGCAACCTCCGCCTCCCGGCTCAAGTGATTCTTTGCCT CACTCTCCCGAGTAGCTGGGATTACAGGCGATGCCACCACACCAGGCTAATTTTTGTATT TTTAGTAGAGACGGTGTTTCATCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTTAAG TGATCCGCCGACCTCGGGTTCCCAAAGTGCTGGGATTACAGGCGTGAGCTACCACACCCG GCCCGTGCTCTGAACATTTCCTTTTGAAGTATGCATTCATCTTTCAGTTTCCCTAATAGA CTTCTTGCTCCTTAAAAGTTAAAAGGACTGGCTGGGCGCGGTCACTCATGCCTGTAATCC CAGCACTTTGGGAGGCCGAGGCAGGCGGACCACCTGAGGTCAGGAGTTCCAAGACCAGCC TGCCCAACGTGGTGAAAGCCCGTCTCCACAAAAATACAAAAAGTAGCCAGGCATGACGGC AGGTTCCTGTAATCCCAGCTACTTAGGAGGCTGAAGTGGGAGAATCGCTTGATCCCGGGA GAATCACTTGATCCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCC AGCCTGAGCTACTAAGCGAGACTCCGTCTCAAAAAAAAAAAGTTAAAGGGACTGAGTTTT GTCCATCTTTGTATGTGGAGCCTAGAACATAATGGTGAGTGCTGAATAATATTTATGAAT GAATGAGGAAACTGAGGAGGACTGCAGAGGAGAAATGAGTTTCTGTCATTAAATTTACAT TTATCAAGTCCTTATTTTCTGTCAGACATCACTCGTAAAGTGCGTAACATGTAACATCAT TAGGTTCTTATAACAACCCCATGTTGCGGAGGAAGAAATAGAGGCAGAGAGATGAAGCAG TTTACTTAAATTAGCCCCACAAGGGATAGCTGAGGTTTGGAAGCCAGAGGCTATGATAGT AATCATCCTCATCAGCTGGACTTCAAATCTATATCCTGGGCTGAGGTTTCTGGCTTGCGG GGTTCCCCAAATCCCACTGCCTTGTCATGGGTCTCCCCAGGAATGCCTCTTTTTACCCAC AGTTTTTGCTATCCCTGCTATATTTTGGCCTGGCTAGGAGATGAGATGTCCTGTATACCC TAGATCACATTTTCCGTTTAATCCTGTGGTTATAGCACACTTGGAAATACCACCCTTTGG ACCGGGCAAGGTGGTTCATGCCTCTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGAT CACTTGATGTCCGGAGTTCAAGACCAGCCTGACCAACATAGTGAAACCCTGTCTCTACTA GAAAAAAAAAAAAATTCCTCAGGCGTGGTGACGGGTGCCTGCAGTCCCAGCTAGTCCAGA GGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGC GCCACTGCACTCCAGCCTGGATGACACAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAC AACCCTTGGAGTCAGAATCTCTACATCATTTTAAGAGTTTTTTTTATGTGTAGCGGTGAA GGGGGCTGGGTAATATTGTGATTGTGGAAGAAAAAGCTGTGTGGTCCGATTATGTGATTA GTAACCAAAAACTTATTTGAGAATTAAAATAGTTGAGCAAAGCATTTAGTGGATTTTGGT GTTTCCAGTATAAGGAGATTAATTTGGTTAATCATAGTGGGATTTCTGTGTATCCATATT ATCAGAGGTAAATAATTTAAAAATAGGCCATTGTCAACCTTTAATGTGCATATAAACCAC CTGAGGATTTAGTTAAAATGCAGATCTGATTCTGTAGGCCTGGGGTATTTCAGCCCGCCC AGGTGATGTCATTGCTGGTGATCTGTGAACCACATTTTGAATAGCCAAGGGCTAAGCCCA GCCAATAGTGGAGGTGTGAAATGGTGGCCTTTTTTCCTGTGGCAGGTGCCAGTGATCCAG ACAAGCCCTTTACATTACTGGGGGTTGGAATTATGGGGAATTTTTACCAGTTTATATCAA CTATGTTAGCAAAAAGAAAAGGAATGATTTTTGAGAAAATGCCCACAAGAGGTCGCTGTT AGCCTTACCAAAGACCCAGAGATTAAAGAAAATGCTTTAACATCTCAGACTTAGGGATCA GAGAGCAAATTTGAGGAAATCATCAAAGAAGTGGTAGAAAATCAAAATATGATGGTTTAC TGTGGGCTTTCAGAAAGGAAAATAAATTTTTTTTAAGATTTATTTCCACAAGCAGTATTT TTTTTTTTGAGATGCAGTCTCGCCTGCCGTAATCTCAGCTCACTGCAACCTCCACCTCCC GGGTTCAAGCAATTCTCGTGCTTCAGCCTCCCGAGTATCTGGGATTACAGGTGTGTGTGA CCATGCCTGGCTAATTTTTTTGTGTTTCTAGTAGAAACGGGTTTTGCCGTGTTGGCCAGG CTGGTCTCGAACTCCTGACCTCAGGTGACCCACCCACCTCGGCTTCCCCCACCTTGGCCT CCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCCAGAAGCAGTATTTTTC ACCACCATCCCCCTTTTTAAAAAAAATAAAATTCGTTCCAAAACTTGGCTCTTTTAAGGG AAATAGACTTAAATTTTAAAGTTCTCAACATGACTTATAGATAATCTATGGAACTACTGA ATCTGATTCTATTGTTGCTCTCACTTTCGACAAGTTACCAACATTCTAACAGCCTCAGCT TCTTCATCTGAAAAATCGGCTTAGTACCTACCTTATTGGGTTGATTAAATGAGGAAACGG AGGTAAAGGCTGGCCCAGAGCCTGGTATACAGTAAGTGCATAATAAATGAGAACAGTCAT TTGATTGTTGCATATGAAGTCATATTTCTGTTTTGATCTAGCGTTTGCTCAGCTGTTGAT TGTTAGTAATTCCAATAGGGACAGAAAACACATTTGGAACAGACTTTCCTGTCACATTCA ATTTTCTATTTTGTTAAATGAGCCTTTCAACATTCTACTTTTCTTGACAACAGATAAAAT TAAGAGTCATTTGAGGCTGGGCGTGGTGGCTCACACCTATAATCCCAGCACTTTGGGAGG CCAAGGTGGGTGGTTCACTTGAGGTCAGGACTTCTAGACCAGCCTGGCCAAAATGGTGAA AGCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGACACACACCTGTAATCC CAGTCACTTGGGAGGCTGAGGCAGGAGAATTGAGTGAATCCAGGAGGCGGAGGTTGCAGT GAGCCGAGATCATGCCACTGCACTCCATCCTGGGGTACAAAGCAATACTCTGTCTAAAAA AAAAAAAGTGATTTGAAAAGAGGAAAAGTGTACTTTGATGTTTTAAACTCCATCTTGACT GTTGATGACTCTTATTCAAATTTATCCTTTGTGTTTTTTTTTTTAAATAAATCGAGGATT GCCTGATAGCATCCTTGATGGGATGGGAGTTTGGAGGAATATTTCATAGGTGATTTCAAT TGCAATCTTTTGGAAGATGAAGATAGTGTATATTTTGTAAATATGACCCCAGAGGGACTA GGCAAATTATCGTGAAAGGGATTTTCCCTTAAAAAAAATAAAAGTAGGGGCCAGGTGCAG TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACGAGGTCGG GAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCTATCTCTACTAAAAATACAAAAA AATTAGCCGGGTGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTAGGGAGGCTGAGGCAGG AGAATGGCATGAACCTGGGAGGCGGAGCTTGCACTGAGCGGAGATCGCGCCACTGCACTC CAGCCTGGGCGACAGAGTGAGACTCTGCCTCAAAAAATAAAATAAAATAAAAGTAGAACT GGTTCATTATTGTCAACCAGCCTTTCTCCTCCTTTCCTACACTTGAAGCCGAGTTCATTT AGAAAGGATAGAAATGAAATGACATGGGAGCTCAATTCGTTTGTGCTGGCTTGGGTTTCT GGGTTAATGGAGGATATTGGGTAAAGCTGACTAGTTGCACGGCACAATTAGATCTGGGGT GCTAGTATTTCATACAAAGGTTAATGAAGTTGGGAATCTAAATGGGAGCAGAAGATGGGG TGGGGGGATGAATTTAAGGGACTTGGAGGCCAGGGAAAGTCCCTGTGCTCTTTGAGGTTC CTCTTTCCCTAAAGTGGGTTGGGAGGGACAAGAATTGTCCCGTGTGCCCAGAAAAGCTGT TTTACTGGGATGGGATATTTTACAAATGAGAAGTGCACATGTCTTTTGTTAAAGAAAAAC TATTGGCTGGGCTCAGTGGCTCACGTTTCTAATCCCAGCAGTTTGGGAGACTGAGGCAGG TGGATCACCTGAGGTCAGGAGTTCGGGGTCAGCTTGGCCAACATGGTGAAACCCCGTTTC TAATAAAAAATACAAAAATTAGCCGGGCGTGGGGGTGTGCCTGTGGTCCCAGCTACTTAA GAGGCTGAGGCAGGAGGATGGCTTAAACCTGAGATGCAGAGGTTGCAGTGAGCTGAGATC GCACCACTGCACTCCAGTGAGACTCTTATGTCAAACAAAAACAAAACAAAACAAAAATAT TATTCATGGTGCTTGTTAAAGGAAATGAGACAGGCTTTATTCCGGGGGGCTACTATAGTG GGGTTTTGCAATAGGGGACAGAGATTGGCCTCAGCTCCTAATGCAACAAGGAATAGTGGG AATTTATAGCCAAGTGGGGGTAGAAGAAGAATTCGATCAGATATTGAGGGCAGCTGGATA TGGAGGGGGATTCTGGCTCAATCAACTTGACAGAATTCTTGCTAAAACTGGGCGGTGCAA ACACAAACATGGAAATCCAATAGCTGAGCACTAGCTGGGGAGAACTCAGAGGAACCTGCC CAGAGTTTGGTCAAGGAGAGACTTTGTCACTTTCCATACTAGCTGAGATGTTCTGCTTGG AGAGTCAATGGAGGAGATGAGAAAGGGGTCAAATGGGTTAACTTGTCTATGACTTTGTGG CCCTGACGTTCTGTGACTATGGTAGCTTTTAAAATTATATGTGGATACACACATTGCATA AACAATTTGGTTAAATATGTGAGTTAAAAAAGATTTTAAACCATAACCTATGAAATTAAA TTCTCAGATCTTCATAATAGAGATTAAGAAATGTAAAGACAATCATTTAAAAACATTTTC TGCCTTCCCCCCACTCCTGTGTTCCTCTCCTTCAGATTTTTTTTTCTTTTTAAGAGAGAG AGACTCATTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATTATAGCTCACTGCAGTTTT GAGCCCCTGGATTCAAGCGATCCTCCCACCTCAGCCTCTAGAATAGCTGGGACTACAGGC ACACACCACCACACCCAGCAAATTTATTTATTTATTTATTTATTTTGTAGAGATGGGGTT TCGCCATGTTGCTCAGGCTGGTTTCAAACTCCTGGGCTCAAGCAGTCCACCCATCTGTAC CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCAGCAGAGAGAATTTCGTAA AAGGAAAACGGATACTTTATTTTCAAAGGAGCAACAATAAGACTACTATTGCAGCACAAA GATGAGCACAGAAGACACAGGGACCGTATCTTTAAAATGCTCAAAGAAGGCTGGGAGTGG TGGCTCATGCCTGTAATCCTGGCACTTTGGGAGGCTGAGGCAGGAGGATCACTTGAGCTC AGGAGTTTAAGACCAGCCTGGGCAACATAGGAAGATGCCAACTCTCAAAAAAACTTAAAA AAAAAAAAAAGAAAAGGAAAAATTCTGTTTGGTTTCTATAAATTTTACTATGAAGGCTCC AAGTGTGTTTTGTTTATTTGCTTTTGTACTTGTCCTACTTGGGCCACAGATGTTTCTTGA GTCTGTAGCTTGATGTCTTTCTTTGGTTTTGGAAAAGTTTCACCTATTATCTCTTCAGAG ACTGTTCTTGCACATTCTCTCTCTCCTCCTCTTTGGGATTCCAGTTATATGTGTGTTAGG CCTTCTCTTCACGTTGCTTGTGTCTTTGAAATTCTGCCTGTCGTCCTGTTCTTTTTCTGC TCCATGCTTCAGTCTCCCCCTTTATTTTCCAGCTCACAAATCCTTTCTCTTTTTGAACCC TCAAGAAACCAATGAAAACACAGTGAGCTCTTCATCTCCTTTCTGCGTGGCTCCTTTCTC TTGCCCTATGCAGCTCAATGGGCGAATACCTTGAGGGGAAATCTGGGCTGGATTTCTGTC TTCTCTGTGCTCTCTCCTCTTCCTCCTGGCTGTCTTGATAGCCCTGAACTCCTGTTTATC TGTGCAGCTCTGTGAGGTTTCCTTAGAGCCTTTTTAGCTGCTCTGCTGCCTCACAGCTGC CCTGTGCTTGGCGTCAGCCTCTTGTCCTGTGCTGAGAATTCACAAATGCCCTCAGCGGGA AAGCTGGGCAAGGAGTGTTAGAGTCACCTTAGTGAGTTTCCCTTTGTTCTGGTGTGTGGC ATAACAAGTCCAGTATGCTGGCAGCTGTTTATACCTTCAAATATATATATATTTTTTGAG ACAGAGTCTCACTCTGTCCCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTTACTGCAA CCTCCGCCTCCTGGTTGAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACA GACATGTGCCACCACGCCCGGCTAATTTTTTGTATTTTTAATAGAGATGGGGATTCACCA TGTTAGCTAGGATGATCTCGATCTCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAA AGTGCTGGAATTATAGGCATGAGCCACTGCATCCGGCCAAACAGATTTTTTAAAATGTTG TGTTTTGTTTTTTGTTTGCCATGGAGTCTCGCTCTGTGGCCCAGGCTGGAGTGGAGTGGT GTGATCTCAGTTCACCGTGACCTCCACCTCCCAGGTTCAAGCGATTCTTCTGCGTCAGCC TCCCAAGTAGCTGGGATTACAGGCGTGCGCCACCATACCCACCGAATTTTTGTATTTTTA GTAAAGATGGTATTTTACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCACGTGAT CCACCCACCTAGGCTGCCCAAATTGCTGGGATTACAGATGTGAGCCACTGCGCCTGGCCA AAAAGTTTGTTTTTAAATGTAGTTTCTTTTTAACTTTGGTGGGAATATTGTGCTGTTCTA AACTACCTTGTCATTGAAGAAGTCTCATCAGAAGTTTTTAGTGTTTTAAGTACCCCCATC CACTAATTGGCTGTGTTTCGCTGTTTACCAGGCACTCCAGGAATAGGAACTACAAAGCTG AATTTGCATCATGCCGACTGGAGGCTGTACCATTGGAGTTTGGGGACTATCACCCTCTGA AACCCATAACTGTAAGTTTTGTTAAGGGTCTTTCTGAATGATATTCTTATCCCTTGAAAT GAAAGACAATCTTCCTGAGTCTTTTCCGTTTTGCCAGTGGTAGCCACTTTTGCATATTTG ATTTTTTTTTTTTTTTCAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGGCTC ACTGCAACCTCTGACCTCTGCCTCCTGGGTTTAAGCGATTCTCCTGCCTCAGCCTCCCGA GTAGCTGGGGCTATAGGCACACGCCACCATGCCTGGCTAAGTTTTTGTGTTTTTTTAGTA GAGATGGGGTTTCGCCATGTTGCCCAGGCTGGTCTTGAACTCCTGAGCTCAGACAGTCTG TCCACCTCCACCTCACAAAGATTATGGGTGTGGGCCACCGTGCCCAGCCTGATTTATTTT TGAGATGGAGTTTCACTTTGTAGCCCAGGCTGGAGTGCAGTGGTGTGATCTTAGCTCACG GCAACCTCTGCCTCCCAGGTTCAAGCAATTCACCTGCCTCAGCCTCCTGAGTAGCTGGGA GTACAGGCATGCACCATCACGCTTGGCTAATTTTTGCTATTTTTTTTATTTTTAGTAGAG ACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACCCTTGACCTCAGGTGATCCAACC ACCTTGGCCTCCCAAACTGCTGGGATTACAGGAGTGAGCCACCTCGCCCGGCCTGCATAT TTAAATCAACCAGTTTGTTCACTGCCTCTTTTTTGTAATATTGGCCTCACCTAGCACCAT TTTTACTCCCTTCCTTCCTCCTTAGTGAGGTTCCCTTGTGAATGGGATGACTTTGTTCCT GATTTGGCTGTGTCAACAAAATGTATCTTGACTTTTAATTTTTGTATTTGGAATATAAGA GTCACTCTAATTGCCAGCAGAGAGTGCTGTCCTGAATAGCATCTTAGTCTATCTGTGGGT TTATTTAAAAAATAAAAACAAAAGCAGGCAAGAGACTTGGCTGGTTCCTCTCTGCCAGGT TGGTACTGTCTTATTAGCAAGTAATAGAAACTACACGGTTGTCATGTTGGGGAGAAGAGA AGATGTGATTGTCAGCATGGAGGCTCTGGGAATGTATGGAGATGATTGCATAAAGCAGAA GACCCCAAGACTGAGATTTAGCCTCCCAGGACCCCTTCAATCCCCATGCTGTTGTGTGGC TGTGGGTGACCTCAGCACAGCCACAGTTGCGTTCATTCTCAGGTGCCCGTTCCCCATGTT AAAAGAAAATTCTTGGCCGGGCTCCATGCCTCACACCCGTAATTTCAGCACTTTGGGAGG CTGAAGTGGGTGGATCACCTGAGGTCAGGAGTTCGACACCAGCCTGGCCAACATGGCAAA ACCCCATCTCTACTAAAAATATAAAAATTAGCTGGGCATAGTGGCATATGCCTGTAGTCC CAACTACTCAGGAGACTAAGAGAGGAGAATCACTTAAACCCAGGAGGCAGAGGTTGCAGT GAGCTAAGATCACGCCACTGCCCTCCATCCTGGGCAACAGAGAGAAACTCCATCTCAAAA AAATAAAAGGAAAATTCTGAGCCAAATTAAATTTAATGGAGCTTAATTGAGCAAAGAATA ATTCATGAATTGGGCAGCCTCCTGAGCCAGAGTAGGTTCAGAGAGGCTCCAGCACAGTCA CGTGGTAGAAGATTTATGGACACAAAAAGGAAAGTGACATTCAGAAAATAGAAGTGAGGT ACAGAAACAGCCGGATTGGTTACAGTTCAGTATTTGCCTTATTTGAACCCAATTTGAACA GTTGGCCCCCCCCTTTTTTTTCTTTTTTTTGAGACAGAGTTTCACTCTTGCCCAGGCTGG AGTGCAATGGCACAATCTCAACTCAGTGCAACCTCTACCTCCCGGGTTCAAGTGATTCTC CTGCTTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGCCCAGCTAATTT TTTTGTCTTTTTAGTAGAGACATGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCT GACCTCAGGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCA CTGTGCCCGGCCCAGTTGGCCCCCTTTAATTGGCCAAAACTTGGTGATTGGCACAAGAGT AGGTTACACTCTGTTTACATGTCCAATGAGGTTATAGTTCACTATGTGCAGAGAAACCTT TAGGCCAAACTTAAAATAGGTAAGGAGACAGCTTTAGGCTAAACTTGATTTAACACCCAT ACCATAACAGAATAGCTGAGAAGAGCTGCTGCAGCTCCAGGCCTATCCTGTTAGGTTAGC AACATCAGCAGCAGGAAAATGCTTTTCTCAAGCAGTTTTCATTGACCCAGTTTTGTTATG CGCCCTACCCTGAACCAGCATTGGTGACCTGCTGTATAGAATAAGTTGATAGATTGGGGT AGGTCTAATGCTCACCTTGGGAACTGAGAACAGAGTTCACCCCACCAGGCCTGTAGGAAC TGAGTGTGGGGGAGAGATGTTTTCTCAAATAAAAATTGGGGTATTAAGTATTAAGCCTGT GAGGTGGAGGAATGGGTGCCAGGCAGACAAAAACAGCAAATGTACCCCAATGGGAGGTGC TTCTCTCCCTCCCCTAGACTGCAGTTCAACTCCATTCAGGCAGCCATCGCCGGCAGTTGG CATCTGACTCGACAGGTTTGAGGGCAAGGTCCTCAGTGAGACAGCCCTGGCCCAGTATGG TAGCTCATGCCTGTACTCCCAGCACTTTGGGATGCTAGATGAGAAGATCCCTTGGGCCCA GGAGTTCGAGAACAGCCTTGGCAACATAGTGATACCCCACTTCTACAAAAAGTAAAAAAA CAATTAGCAAAGTGTGATGGTGTGCTTGTAGTCCCAGCTACTCAGGAGACGGAGGCAGGA AGATTGCTTGTGCCCAGGATGTCGAGGGTACAGTGAACCGTGATCACACCATTGCACTCC AGGCTTAGTGACAAAGCGAGACCCTGTCTCCAAAAAAAAAAAAAAAAGACATCTTCACTT CAGAAACTCCAACTTCGCTACACATTGGGAGTTCCCATGCCTCCCTCCCTCATGTTCAAT AATTTGCTATAGTGGCTCACAGAACTAGGGAAACATTTACTTATACTTACCAGTTTATTA TTTAGTATTTACTTGTACTTAACAGTTTATTATTAAGGATATTACAAAGAATACAGATGA ACAGCCAGATGAAGAGCTACGTAGGGTGAGGCCCAGGGGAAGGGGCACACAGAGCTTTCA TGTCCCCTCCAGGTACCTCGATGTGTTCTTGTTCACCTACCTGGAAGCTCTTCAAACCGC CCCCCCCTTTTTTTTTTTTGAGACAGGGTCTCACTGTATCGCCCAGCTGGAGTGCAATGG CACATTCTCAGCTCACTGCAACCTCTGCCTCCCAAAACCCCATTTTTCATGTTTTTTTTT TTTTGAGGCATCGTTGCATAGGCATGATTGATTATTCATTCGGTCTCCAGCCCTCTCACC TTCCCGAAGGATGGGGAATGGGGCTGAAAGCTCCAATCTTCTAATCATGGCTTGGTCTTT CTGGTGACCAGACCCCATCCTGAAGCTCTGCAGGAGCCCATCGGGAGTCACCTTATTAGG ACAAAAGATGCTCCTATCACCCAGGAAATCTCCTAGGGTATTAGGAGCTCTGTGGGAGGA ACTGGGGGCAGAGACCACATAAATTTAACAGCTTGGAGTGCAGTGGTGCGATCTCGGCTC ACTGCAACCTCCACCTCCTGGGCTCCAGCCATCCTCCCACTTCAGCCTTCTGAGTAGCTG GGACCACAGGCATGTACCACCACACCTGGATTATTTTCATATCTTTTGTAGAGATAGGAC TTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTGGCTTCAAGTGATCCTTCTGCCTCAG CACCACAAAGTGTTGGGATACAGGCATGAGCCACTGCACCCAGTAGAAAACTTAACTTTT ATGAGGTGTTCAAGGGAGAAAGGCAAAAAAAAAGTACCTGGTTAAAGTAGAAATTCCCTA CTTAGATGTTAGTTGTTGGTTTTGATTGGTAGTCTCTAGTTAGTGGGTAGTTGGCGATTT GCAACTGATTAAGCTTAAGTTCCATTTTGCTACTTATATTGAGTTGGATTTTGGTTTGCT ACATAGGGAACCCCAGGTGCTGTAGCCATCTCAGTCCAGTGACCTCTCAATTAATTTTTT TAACACTTCCTAACCCTAACTTCCTACTTTCCCTTCCTTGACAGTTGTGATCCTGAGTCA TGTCCATTTGTCACAAAAACTAAGCATCCCCTGCAGATGGTTAAGTCTCTGCTGCAAATG AACCATCCATTCAACTACCAGAATGGGAGGAAAGTACCCACTGGAGTGTTTCACTGGAGA GAGTTGTGGGAGTTCCGTTTTACCTCCAGAAATTTTCCTCACAGGTCACAGAGTCAAAGA CAAAGAAAGTGAACCGGAAAGGAAGCACTTCTTCCACGTCCTCCTCCTCCTCCAGCTCCG TGGTGGACCCGCTGAGCAGCGTCCTCGATGGGACTGACCCCCTCTCCATGTTTGCAGCCA CTGCTGACCCCGCAGCCTTGGCAGCTGCCATGGTAATGCACCCCAGCCATGGTCGTCCAG TGGGGGTTGGTTTTGTGGGTGCAGGAATGGGTGGTTTTCTTGTGCCCTGCCCTTTTTTTT CCCCTGAGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGGTCATGG CTCACTGCAGCCTCCAACTCCGGGGCTCAAGCAATTCTCCCACCTCACCCTCCTGAATAG CTGGGATTATAGGTACACACTACTGTGCCGGGTTAATTTTTTATTTTGTTGTAGAGGTGG GGTCTTGCTGTGTTGCCCAGGGTGGTCTTGTACTCCAAGCCTCAAGCGATCCTCCCACCT GAGCCTCCTAAAGCTTCTTCCCCTTTTTTAAGTTGCACAAGTAATGCACACGGTACCTTC TGGTCAGGTCATCCTGACATGAGAGGCTGGTGTAGCTCTGTGAAGTCTTTTTGTTTTTTT GTTTGAAAGCATTTTAAAATTTATTTTTATTTTTTAATTTAATATTTTTTTCAGACAGCC TTGCTGTGTCACCCAAACTGGAGTGCAGTGGTGCAATCTCACTGCAGCCTCCGACTCCGG GTTCAAGCAATTCTCTCACCTCAGCCTGCCAAATTGCTGGGACAGGCATGCACCACCATG CCCAGCTAATTTTTGTGTTTTTTGGTAGAGATGGGCTTTCATCATGTTGACCAGGCTGGT CTTGAACTCTTGACCTCAAGTGATCCACCTGCCTCAACCTCCCAAAGCACTGGGATTACA GGCGTGAGCCACTGCACCTGGCTCTTAAAATTTATTTTTAATTTTAATTTTATTCTTCTT ATAAATCTTTTTACATAATACATAAGTAAATCACTCATTTTGATGTGAAAAAGTCAGACA CTACAGATAAAGTCATGTAGAGCAATCCTCATTCCAATCTCCACCCTGGCGGTTGTGAGA ATGATGGCTGTAATGTGTCTTCTTCCATAGCTTTTCCCCTGTATTTTCATAGATACTTGC GATAGCAGTTTCTGAGCATTCCCATACGTACTCATATATAAATAATTACAGCATCAACTT ACTGCATGGCAGGCATTTTTCCGGAGTGCGTTTTGTATTTGGTTCTCTTACTACCTTGTG AGAGGTATTGGAATCCTCATTAAAGAGGCAGCCATGGAGGGATAGAGATAACAAGTCACA TCCAAGCTGGGATTCAAACCTGGCCAGTCTGACTTCAGAATACATGCTCTCGATCATCAT CCTATGCTGTGTTTCATATATATATATATATATATATATATATATATATATATATATATA TATATATATATTTTTGAGATGAAGTCTCACACTGTCACCCGGGCCGGTGTGAAGTGGGGT GATCTCGACTCGCAGCCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTTCCG AGTGGCTGGGACTACAGGCACGTGCCACCATGCCCAGCTAATTTTTGTATTTTAGTAGAG ACGGGGTTTCACTATATTGGCCAGGCTGGTCTCGAACGCCTGACCTCGTGATCCACCCAC CTCGGCCTCCCAAAGTGCTGCAATTACAGGCGTAAGCCACTGTGCCCGGCCTGTGTTTCA TATATTATTTACCATTGTTACATAAATGGAACTGCTGTTTTGTGACTTGTTTTTTTGGAG ATAGTCTTGCTCTTTTGCCTAGGCTGGACTGCAGTGGCATGATCATAGCTCGCTGCAGCC TTAAAGTCCTGGGCTCGAACAATCCCCCTGCCTCAGCCTCTCGAGCAGCTGGGACTTCAG GTGTGTGCCACCGCACTCAGCTAATTTTGGATTTTTTGGTAGAGTTGGGGTCTCACTGTG TTGCCAAAGCTGGTCTCAAACTCCTGGGCACAAGCAATCCTCCTGCCTTGGCCTACCAGA GTTGCTGGGATTACAGGCCTGAGCCACTGCACCCCACAACTTTTTTTTTTAATTTATTTT ATTTTATTTTATTTTATTTTTTTGAGACGGAGTCTCATTCTGTTGCCCAGGCTGGAGTGC AGTGGCGCGATCTTGGCTCACTGTGACCTCTGTCTCCTGGGTTCAAGTGATTCTCCTGCC TCAGCCTACCTAGTAGCTGGGATTACAGGCATGTGCCACCACACCTGGCTAATTTTTGTA TTTTTTGTAGAGACAAGGTTTCGTCACATTGGCCAGGCTGGTCTCGAACTCCTAACCTCA GGTGATCTGCCCACATTGGCCTCCCAAAGTGCTGGGATTACAAGTTTGAGCCATGCCGCC CAGCCAACTTTTTTTTTTTTTTTAACTTGACCATATGTCTTGGAGAACTATCCATGTTAG TACATTTAGAACAACCTTATTATTTTGACCAGCCGTATGGTATTCTAAAGACTGGATTTA CCTATTTTAATTTACCATTCCTCTACTGATGTATCCATCAGATGGAGGATATCCCAGATA GTTTCTGGGTTTTGCTGGTACAAACAGCAGTGCAGCATGTGTCTCGAACACACACACATC TTGGTGCATGTCTGCAAGGATTTCTGCAGGATAGCTTCCTAGAAGTTCTTTGCTGGTTGG CCAGGCGCAGTGGGTCACGCCTGTAATCCCAGCACTTTGGAAGGCTGAGGCGGGCGGATC ATGAGGTCAGGAATTCGAGACCAGCCGGACCAACGTGGTGAAACACCATCTCTACTAAAA ATACAAAAATTAGCCAGGTGTGGTGGCGGGCACCTGTAATCCCAGCTACTCGGGAGGCTG AGACAGGAGAATCACTTGAACCTGGGATGCGGAGATTGCAGTGAGTAGAGATCACGTCAC TGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCTTTGCTGGCATAAGGCAATGTG TATTTAAGGTTTTGATGGCTATCACCAAATTGTCCTCCAAAAAGAGTTAACCAGTCTGCA TTTCCACCAGTGATGTTGAAGAGGGTCTGTTTCCCTGCATCCTTGCCAGCCTGACATCAG CCAGCATTTTAACTCTTTGACATTCTGATAGTTGAAAAAGTGGTCTTTTCCAACTATCCT TTCCTTAATTCTTAATGAGTTTGAGCATTTTTTGATATGTTTATTGTCCATTTATGATGA AATGGTCTGAATTTTTTTTTTGAGATGGAGTCTTGCTCTGTCACTCAGACTGGAGTGCAG TGGTACAATCTTGGCTTACTGCAACCTCTGCCTTCCAGGTTCAAGCGATTGTCCTGCCTC AGCCTCCTGAGTAGCTGGGACTACAGGCATGCACCTGGCTAATTTTTGTATTTTTAGTAG AGATGGGGTTTTACCATGTTGGCTAGGCTGGTGTTAAACCCCCGCCCTTAAGTGATCCGT CCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGGCACCATGCCTGGCGCTGTA ATTTTTTTTATGATAGTAAACCTTGAGACAAATCTCTTTTATTCCACAGTAAAGGACTAT CTGGCTTCTATTTATATATGTATATATTTAAAGATCAAAATGATATTGCTGCTGAAGAGA TTATCTTGCCTTTCTTTAGGACAGCTCCAGAAGGAAACGTGATAGAGATGATAACTCCGT TGTAGGATCGGATTTTGAGCCTTGGACCAACAAACGGGGAGAAATCCTTGCCCGGTACAC CACTACCGAAAAGCTGTCTATTGTGAGTACCAGGAGACCCTCTCCAGAGTCTACTTTGGA GTTAGTAGTAATTTCTTTTTGTTATGTTGCTTCAACTCCTGGGCTCTGTAAGTTTCACTT ATTTATTTATTTTTCTACTTCTCTTAAAAGCTCACATATAAGGCTTCATGTAGTATGTCA GTGTTGTTGGCAGAAAAATGTGCTGACAGGTTTCCCAAAAAAAAATGTTAAGGATCAGGG ATGTGGCACAGGCCAGAGAAAGAATTAGAACAGCAGAGTCTTGTCTTTGGGAGGAGGTTT GAATTATGAAGGGAGGAGGTCGGGCACGGTGGCTCACGCCTGTTATCCCAGCACTTTGGG AGGCCAAGGTGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATAGT GAAACCCCATCTCTACTAAAAAAATTAGCCAGGCGTGGTGGCGGGCACCTGTAATCCTAG CTACTCAGGAGGTTGAGGCATGAGAATTGCTTGAACCCGGGAAGTGGAGGTTACATTGCG CAGAGATCACGCCACTGCACTCCAGCCTTGGTGACAGAGTGAGACCCTATCTCAAAAAAA ATTAATTAATTAATTAATTTAAAAAATGAATTAAGGGAGGAGAGCACAACACTGGAGGAG AAAGGTGTCACTCAGTAAGTCCCATATAGCTGGGTTTTCCCCTGGAGCTGGAAATTTACT ATTTCTCTGGATGGCCATTAGGTGAAGTAGTTGGCTTTGGCCTCAAGACACTTACGAAAT TCGAGGCTTACCCTTCACTTGGCAAATTGCTGTGGAAGGAAAGACTCAGGAGAGCTGAGA CCAACCCAGTCAGGTTAATGCCTGTGTGAGTTAGGACTGGGTTCAGTTGCTTAGAACTAA AGCCCCTGCTAACATTGTAAACAAGAGTGACCTGTATCCCTCCTTACGCTGGAGAAAAGT CTCGAGGAGAGGAGTCCAGGGCTGGTTTGGCAGCTCCGAGGGCATCAGGGTTCCGCCGCA TTCTTTCTTGCTCCTCGGCTGTGTTGAGTGTTGCCTCACATTCATGTTGGTAGACAGAGG GAGGAAAGGGAAAGAAAGATGCGCCCCCTCCCATTTAGGAAGACTTCTTGGGGTCCCGCA ACACTTTTAGTTACATTTGTCTTGAAGGTGTGATCATGGGCCACGCATAGATGCAGGGAG GCTGAGAAATGTAGCAGCGTGTCCATCTACAAATGGGGCTGTGCCCTGGAGGAAACAGTG AACTTGGCAGGCCATGGGGAACGCTTGGCCTCAACGCCTCTTCTCTTCATTTTTTCCTCC CAGGGTGTGTACTCATTGAACAGAATGATAGGCAGAATTGCTGGACTATTTAAATTGAGT CTTTTTTTTTTTTAACTGTACAGAGTTAACTTAGAGCAGTGATTCTCAACCAGGAGTAAT TTTTACCCCTGGGTCATCATTTGGCAATATCTAGAGACATTTTTGACTGTCACAGTTCTG GGGGTGGTACTGACATTTATTGGGTGGAGGCCAGAGATGGGGCTAAACATCCAACGGTGC ACAGAATTAATCTCCCACAAAAAGTTATCTGGCCTCAAATGGCAGTAGTGTAGAGGGTGA TAAACCCTGATTCAGAGTAGGTTAAAAATAGTTCTATTATGTGACTCCGCTGTCATATCA AAAATTTTAGTATTTGTCTGCTGACTTTGAGAACCCTGACTTGAGTAGAAATTTGAATCT CCAGTGGTTTTTAGTGACTGTATTTTTCTTCTTTGAATATATATTTCTTTCTCTTGGGTA TGTAAATGGCTCTGTTGGAAAACAATGAACATACTGCCTTCGATTTTTAAAATATTAATG AATTTTATGTCTCTGCAGAATCTGTTTATGGGATCTGAAAAAGGTAAGATGAGTTTGTTG TTGTTTTGATGGGAAAATTCTGGCATTACTTTTAGTATAATTTTACAAAGGAAAAAAGTT TTATGTGATATGATTCTGATGTTTGATTCAGTTGGAGCTGCTATTTCTTAGATTGTGGAT AGACGTAGAAATAAAATACATATTTAGAGCATGAATTAAAAAAATACCAAATACCAGCAC TTTGGGAGGCCAAGGTGGGTGGATCATCTGAGGTCAGGAAGTTTGGTACCAGCCTGGCCA ACATGGTGAAATCTCGTCTCTATTAAAAATACAAAAATTTGCTGGGCGTGGTGGCGCACG CCCGTAATCCCAGCTACTCAGGAGGCTGAAGCAGGAGAATCACTTGAACCTGAGAGGCGG AGGTTTCAGTGAGCCAAGATTGCATCATTGCACTGCAGCCTGGGTGACAGGAATGCCGTC TTAAAAAAAAAAAAAAAATACAGCCGGGCACGGTGGCTCACCTGTGTAATCCCAGCACTT TGGGAGGCCAAGACAGGCAGATCGCCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACA TGGTGAAACCCCATTTCTACTGAAAATACAAAATTTTGCTGGGCGTGGTGGTACATGCCT ATAATCCCAGTTACATAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAAG TTGCAGTGAGCCAAGATTGCACTCCAGCCTGGGCAACAAGAGTGAAATTCCGTATTAAAA AAATATATATATATGGCCTGGTGCGGTGGCTCACACCCGTAATCCCAGCAGTTTGGGAGG CCAAGGCGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAATGTGAA ACTCCATCTCTACTAAAAAAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGACAGATG CCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGG AGGTTGCAGTGAGCCAAGATCGTGCCATTGCATTCCATTCTGGGTGACAGAGCGAGACTC TGTCTCAAAAAAAAAAAAAAACAAAAAAAAAAAACAAAGAGGTTACTAGGAGTAAAACGT AAGCTTACTGTTTAAGAATTACAGAGGAAGTAGTCTCCCCCTCATTGTGCCTCCCTCACC AACTGGGTTTTAGAGAGCCTTTCCCTTGCCTTAAGTCTTTTCCCTTGTGCAATAAGGTAT GTTGGTGAGGGGGTCACATGCTTAGTCTTATACGTCACTGGTCCCTGAATGCAGTTCTCA GCTTCCTCTCCTAAGACACACAGTCAGAAGCTCTGGACCAGGGTGTCTCAAACTGCCGTG TAGCAGGATTTCCTGAGGAACTTTTGTATGAATATAGATGCCTGGCCCCCACTTGCTCAA TTAATCTTGCAGGATGGGACCCCAGAATTCCTATTTTGATGCTCCAAGGGGATTCTGGAG CAACTGACGGATCATGTGCTGCTGGGTGCAGATGAGCACAATCATAGTTCATTGCAGGTC TCTGATATGGCAGCTGCCACTCTCCCCACGGCTCTGCTGGATGAGACAGCACGTTAGAAA TCAAGAGAGTGGGAACAGCTTTGTTATGCATAGAATTTTTTTTTTTTTTGAGATGGAATT TTGCTCTGTCACCCATGGTGCAGTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCCA CCTCAGCCTTCTGAGTTACTGGGACTATAGGTGTGCACCACCAGGCCCAGCTAATTTTTG TATTTTTAATAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCTTGACCT CAAGTGGTCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTACCACG CCCAGCTTGTTATGGACAGAATTTTGATCCCAGACCATAAAAGGTAAATCATACCCACCA GTTTGTAAAGATCAAATAGAGTGATGATACCAAGTGTCTTAGTTTGTTTAGTGGTACTAT AAAGGAATACCAGAGGCTGGCTAATTTATAAGGAAGAGAGGTTTACTTGACTTATGGTTC CACAGGCTATATAAGAAGCATGGTGCAGCATCTGCTGTTGGTGAGGGCCTCAGGCTGCTT CCACTCATGGTGAAAGCAAATGAGAGCAGGTGTGTGCAGAGATTGCATGGCAAGAGAAGG GAGGAGAGAGAGGGAGAAAATGCCAGGCTTTTTTCAACAGCCAGTTCTCATGGGAAGTAA GAATAACTCATTACTGCACTCATTACTGCAAGGATGGCACCAAGCCGTTCATGGTGGATC CCCCACTACAACCCAGACACCTCCCACCAGGCCCCACCTCCAACACTGGGGATCACATTT CAAAGATGAGACTTTGTATGAATATAGAGCAATAGGAGCTCTCATATGCTGCTGGTGGGA ATGTAAAATGGCACAACCACCTTGTAGAACACTTTTGCATTTTTTATTTTATTTGAAGAC AGGTGCTGTGGTCTGGTTGTTTGTGCCTAACCCCACTCCCCTGCCCCGATTCATATGTTG AAATCCTAACCCCAAGATGATGGTATTAGGAGATGGGCCCTTTTCAGAGGTGATTAGGTC ATGAGGGTGGAACCCTCATGAATGGGATTAGTGCCCTATAAAAGAGGTCCAAGGGCACTC CCCTCACCCCTTCCACCAAGTGAAAACACAGCAGGAGGGCATCATCTATGAACCCAACCG GAAAGCAGGCTGTCATCAGGCACTGGGACCTAATCTGCTGGGACCTTGATCTTGGACTTC CCAGCCTTTAGGACTGCGAGAAATACATTGCTCTTATTTATAAGCCACCCACTTTGTAGC ATTTTGTTATAGCAGCTCAAAGGGATTAACACAATGAGCCAACCCTTTGATCCAGCATTC CACTACTAGGGGTATCCCCAGATCAGGGGTTGGTAAACTGCATGCTGCAGGCCAAGTCTG GTCCACTGCCTGTTTTTTAAGTACAGTTTTATAGGAACAGAGCCCTATCAATTTGTTTAC ATATTATCTATGCCTGCTCTTGTGCTACAACAGTAGAGTTGAGTAGTTGGAGCAGACACT TTGTGACTCTTAAAACCTAAAACATTTGTCAGGCTTACAAAAAGAGTTCTGCAGCTCGAC CCTAAGTCCACATTTCTTTCTTTTTTCTTTTTTTTTTTTTTGAGATGGAGGTTACAGTGA GCCGAGATCGCGCCACCGCACTCCAGCGTGGACGACAGAGTAAGACCCCATCTCAAAAAA AAAAAAATGCTAGAACAGAGGCCCCCTAAAGATGGGGGAAGGATTCTGAAATAGACGGCC GCAGAGGGCAGCAGTCAGCTAGATGCATCGCCCTGCCTTGTGGCTGGCCTGTGGCCTGGG GGCCCTTCCTTCATCCCTCCACCAGTCCCTGCTGATGGCGAAATTGTGCTGACAGATGCT GGAAGGAGGCACAGCTAGTCCTGTTTGCTCGAAGAGAGGGCTTTGAAGCCCTAGTGTTTC CACCCTGGGTAGACAGTGAGATGGTTGTTTTGTTAGCAGGAGAGCACAATTCTACGCTGT GAGTAAGAGCCTAAGAGGGCCTTTTGTTCATAGAAAACAATTAGATGACGGATTTTTGGC ATCCTTATCTGGACTGCCTTTCTTTAGGAATAAACAGATGATACAGAGCAAAGTTTGTAA ATCTCAAATGCAGCGGTTAACCTCTTTGAGGCTGGCCCACTGGGCTCCCAGGGGCAGCTT CTAAGTGGGAAATGTTTCGATGGAATTCTGGTTACATAAGGAAGTTGCTTTGAAAATCTG GGATAGTTTTCTATAATGGAATCATTCCCTTGTGTCTTTATTCACGATGAAGTGTAGAGT GAAAGATGCCTCCACTGGGGGTATTGGTGCACGAGAAAAGCCACCTGTGTGACGTAAATT CATTCTGTTTAGGCAAAGCTGGGACTGCCACATTGGCAATGTCAGAGAAGGTGCGGACCC GGCTGGAGGAGCTGGATGACTTTGAGGAGGTGAGCAAGTCATTTGTGGAATACAGGGAGT GGGAGAGCTTTTCCTTCCTCCTGCCAAGTGAGATCAACCTCGGTGGCTGCTCTTTGATTA ATTCCTGGGCTGCGCATTGTGCTTGGTCCTCTCGAGGCAATGACTCCATCCAGGGAAGGG TGCCAGTGTGCAGTTGGCCGAGCTCACGGAAGCCTGACTGGGGCTGCTTTTCTAGAGGCC TCTTTTCTCATTGTGATGCCTGAGCAAGGCTGGGTCGCCTAGCAACAGTGTCTAATGGTA AAAACCAACTGCAAGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGG CCAAGGCGGGAGGATCACCTGAGGTCAGGAGTTCGAGACCAACCTGGCCAACATGGTGAA ACCCTGACTCTACTAAAAATACAAAAATTAGCCAGGCGTGATGGTGGGTGCCTGTAATCC CAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTAAACCTGGGAGGCGGAGGTTGCAGT GAGCCAAGATCATGCCACTGCACTCCAGCCTGGGCGAAAGAGCAAGACTTTGTCTAAAAA AAATAACCCAACTGCAGTCACCTCCCTGAGAAGCAGCCTTATATGGAGCACAAAGACCTT GCTTTGCAACAGACGCTGCTCAGGCTGGCTGGATATGGCCCACAGGAATCTTTTAATTGG CCTACATGTACTTTGAAAAAAAAGTGAGTCTTTTGCCAACACTTAAACAGTGGTAAATGT AACCAACAAATACAGAATTTCTTGAAAAAAAAAATCTTTGCCAGGCGCGGTGGCTCATGC CTATAATCCCAGCACTTTAGGAGACCGAGGCAGGTGGATCTCCTGAGGTCAGGAGTTTGA GACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGG CATGGTGGCGGATGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGTAGGAGAATTGCTTG AACCCAAGAGATGGAGGTTGAGATCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGAT CTCAGCTCACTGCAACCTCTGCCTCCTAGGTTAAAGCAATTCTCCTGCCTCAGCCTCCCG AGTAACTGGGATTACAGGCACGCGCCACCGTGCCCAGCTAATTTTTGTATTTTTAGGTGA GAGGGTTTCACGATGTTGACCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCG CCTCAGCCTCCCAATATGCTGGGATTACAGATGTGAGCCACCATGCCCAGCCTACTCTTA TTTCTTTAATAAAGCGTTTTTCACTTTGAATTGTAGGAAATATACATATAAACCTTTGGT TCCAGGTCTCATCATGTGTGTTTGCATGACCTTCACTCCTGTGAGTTGTGTGAAGAGCCT CTTAACAATAGCCCAGGGTTAAGGAGCATTTACTGTGCGTCAGGGACCGTGCCAAGTCAT TACCTACATGGTCATTTCATCCCCATGACGATCCCTTGCTCAGCTGCCGAGGGTTTTTGC TATGGTTGTCTTTCTGTCCTGATTACTCTCTCCTTGGTCTAATTAACACCCCCACACTCT GCAGTACCTGTACTCCCCTGAGAGTTTGTCTCAAGTATCACTCCTCCAGGAAGCCATTCC TGATCCCCCCATCACAGTTTACAGTCCATTTCTTTGTTACCATATTTTTTCCAGTCTGAG ATGTACCATTTCTCTCACATTTGAATATCTCTGAAATTGGGGTATATGTTCCTCAGTTGG TTCCTGTCAGTGATCAGCATATTTTTCTTCCTTAGTAGCCCGTGAAACAGTTGCGCTTTT TTCAATGGGCACCTCAGATCCAGTATATGTGTCCCCATAGAATTGTGTTTTCTCCTGAGC ATTTATCTCAGTTTGAGTTAATATCCGTCTGTCTTCAGAATCTTAAGCTCCATTAGTGCT GAAATACCCTGTCATGTCTTATTGCTTGGGAATCTTGAGCAAAAATGTCTTTGTATCTCG ATCATCTAGTCCCATGTCCTGCACACAGGGGGCCCACAGTTGGTTGAATGAGGTAAGTCT TGTTACCTCAATTCACAGATGAGGCTGTGAGAGGAAAATAGCTTACCCAGGGTCACACAG CTACTTGGTGTCCAAGCTGGGAGGTGGCTTAGGTCTGACTTGCTTCCAAGGCCAGACTTT CAACCCACAGCACTCTGTCCATCTTTGTCAGAAAACTCAAAAGAACCTCTTTGATTGCAA ATTGCAAGGCAAAGCTGTCAATCCTGGCGGGGATATGAGGAAAATTTAGAGACCAAAACT CAGCCAATACCTAGTATTCTTTATAAGGGTGTAGTCGAGCAATGTTTTTCCTGCTATGCC TTCACCTTCTGCCTTCTCCCCACAGGGTTCCCAAAAGGAGCTGTTGAACTTGACTCAGCA GGATTACGTGAACCGCATAGAGGAGCTCAACCAATCGCTGAAGGATGCCTGGGCCTCAGA CCAGAAAGTGAAGGCTCTAAAAATAGTCATCCAGGTTAGCTCTAGTGATCCCCCACCCCC ACCCAGAATTTCCTATGTAAAATTCCACTGTGAGACTTAGAGTTTTCAGGGGCCTACCTG CAGGGTCTTACTCTTGTTTTCTCATCCCTTTCTTTTTCATATACTTCCTGTGAAAAGCCA TGATTATGAATCTGTGTTTTTATGAGATGGCTAATCCCAGGGTTACCATGTGCAGCTGCA CAGGTTGTGCACTGCACAACTCCAGGAAGCACTCTTCACCCTAGGTTACAGAACTGATGA TACCCCATGTGTTGTGCAGTACATTAACCATGGTGCAACCCCTGACACATTTATGATTTG TACACACTAAAGATTGAGCAACTTTCTTTCGGGATTCCTTGACCGCATTCGCTTGGTGTC TTTGGGATTAATGACGTGTCCCTAATAAATGAATATTTCAGACATATTATGCATGCTTAT GTGACAAGGAGAAGTTTACAGCGTTGGGAGAGGTACATACATTGAATCTTCTTTGTTGAT GAATTTGTTAAGCCAGTGACAATTCTTGAACCACAAGAACAAGTACTATGTGGAAAACAG CTTATATGTCTTGGTCCTAAAGATCCTGCTGTCTCAGCAAAATGTGCTCAGAAGCATATT TGGAAAGGAATAATTCATTAAATTATCATTTTCAGAGCAGAGTCTACAAAGGATTTCTGA ACTGCCATTTTAGTTCAAAAGGACAGATCCCATTCTCATTCCATGTTATGATAATGTGAC ATTTGTTTTCTCACCTGTTCTTTTGAAAGACAGGAGAGTCCGGGAGTCTTCACACTGGAC ACATGAAGTCTTTTAAGATGACTCCTTGTATAGTACGGGTGATTTCTTTGGTATTTCATG ATGGGAGGCAAACCCACGCCCGTTTCTCTTCAATCACTGTTGTTAGTTTACAGAGTAAAT AGTCCCGAAGGCCAGGCCTCTCATCCTGGAAGCCCGTGGAGAGGGTTGCTTGCTGAGTGT CTCGAGTGAGAAACTATCTGAACTAACAAGTACTTCTTCACAATATTTGCATTGGCAGCA TCTCTCCGTAGATTATTGTAGTTTAGAACTGTGTCTTCTAAGAGGTTTACATCTGGGGGA GATTTGATTCATGTCTTCACAAACAAAATAATCATTAAGTGTGTTTCATCAACTCCACAT CTGGCTAATAGTAACGATTCAACAATACATTAAGGACTGCCTTCTTTATCCAAAAGACAT AGTCAAGGCTGGGCACAGTGGCTCACATCTGTAATCCCAGCATGTTGGGAGGCTGAGGCG GGTGGATCACTTGAGTCCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCATCT CTACTAAAAATACAAAAATTAGCCAGGCTAATTTGCTATACGGTAAAGTTTTTTTGTGTG TGTTGGGGGGGTACCCAGTGGCTGCTTTACTAAGGCATATTTTACATATCATAAAGTCCA CCCATTATAAGTGTGTAATTCATTGATTTTTTTTTACTTAACTTATAGAGTTGTGCAACT AACACGCAATCTAGTTTTAAAACATTTTTATACCTCCCCAGATTCCCCCGAGCCTGTCTG TAATCAAACCCCACTGCCATACCCAACCCCAGAAAACCACAAGTCTGTTTTCTGCCTTTA TAAATCTACCTTTCCTGGATATTTCATATACATGGGATTATTCAATAGATAATCTTTTGG ATCTGGCTTCTCTCACATAGTGTAATGTGCCTTTTTAATTGATAGATAATAATTCTACAT ATTTATGGGGTACAGAGTGATATTTTGATACATGTATCCCGTGTGTAATGATCAAATCCA AGTAATTAGCATATTCATCACCTCACACGTCTCTGATTTCTTTGTGTTGGGAACATTCAA AATCTTCTCCTCTAGCTATTTAAAAATACACAATAAGCTGGGCCTCGTGGCACACCCCTG TAATCCCAGTTACTTGGGAGGCTGAGGCACGAGAATTGCGTGAACATGGGAGGTGGAGGT TGCAGTGAGCCGAGATCGCACTACACCACTCCAGCCTGGGTGACAGAGTGAGATTGTCTC AAAAAAAAAAAAAGGAAAACAGAAAGAAAAGAAAATACACAATAAATTTTGGACTATAGT CACCCTAGGTGCTATTGAACACTAGAACTTATTCCTCATATGTAGCTGTAATTTTGTACC TGTTAACCAACCTCTTTGTTCTCCCCTTGCCCCTACCCTTCCCAGCCTCTAGTCGTCGCT GTTCTACTCTCCACTTCTATGAGCTCAACTTTCATAGCTCCCACATATGAGTGAGGACAT GCAGTATGTATCTTTCTGTGCCTATTTCACTTAACATGATGGCTTCCAGGGTCATTCGTG TTGCTGTGAATTACAGAGTTTCATTTTTTTATGGCCAAATAATATTCCTGTGTGTGTACC ATGTTTTCTTTATCCATTCATCCATTTATATACATTTAGATTGATTTCATATCTTAGCTA TTGTGAATAGTGCTGCAGTAAACATGGTACTGCTGGTATTTCTTTGATATACTGATTTTC TTTTCTTTAGATGATAACCTAGTTGTGGGATTGCTACATCATATGGTAGTTCTATTTTTA GTTTTTTGAGAAATTTCCATACTGTTTTCTAGAATTGTTACACTAATTTGCATTTCCACC CATAGTGTGTAAGAGTTCCCTTTTCGGCTGGGTGTGGTGGCTCACGCCTGTAATCCCAGC ACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCC AACATGGTAAAACCCCATCTCTACTGAAAATACAAAAATTAGCTGGGCATGGTGGCAGGT GCCTGTAATCTCAGCTACTTGGGAAGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCA GAGGTTGCAGTGAGCCAAGATTGCACCATTGCACTCCAACATGGGCAACAAGAGCAAAAC TCTGTCTCAAAAAAAAAAAAAAAAAGAGTTTCCTTTTCTCTGTATTCTTATCAGCATTTT TTTTCTTTCTTTTTGTTTTTTTTTATTAAGAGATGAGGTTGCCCAGGCTGGAGTGCAGTG ACTAGTCACAGGCATGATCATTCTGCATTACAGCCTAGAAGTCCCAGACTCAAGTGATCC TCCCACCTCAGCCTCCCAAGTAGCTGGGACTATAGGCACATACCACCATGCCCAGCCTAT TTTTGTCTTTTTGATAGTAGTCATTTTCATGTGGTTTTCATTTGATGATTCCCCTGATGA TGAGTGATGCTGAGCATATTTTCACATACTTGTTGGCTAATTTGTGTATCATCTTTTGAG AAATGTCTCTTCAGCTCTTTTGTCCATTTTTTAATTGGATTATTTTCTTTAGCATAATAT GTTTGAGGTTCATCCACATCATATTACATGTGGGTAGTTCGTTCCTTTTTACTGCTGAAT CGTATTCTAATGTGTGGTTATCTTAACAAGTTGATGGGCATTTGGGTTGTTCCCACTCTC TGGCTGTTATGAATAATGCTGCTCTGCACATTTGCGTACAATTATTTGCGTGGACTTACA TTTTTATTACTCTTAGGTAAAATTTTAGGAATGGAATTGCTGGGTCATATGGTAAGTTAG GATTAACTTGATGAGAAACTGCCAAACTATATTCCAGATGGCTGCACCATTTACCTGAGG GTTCTAATTCCTCCACATCTTCTCTGACACTCGGTATTGTCCATCTTTTCTTCTGTTTTC TTTTTTCTTTTTTTTTTTTTTTTTTGAGACAGGGTCTCTGTCACCCAGGCTGGAGTGCAG TGGTGTAATCATAGCTCACTCCAGCCTCAAACTCTGGCCTCAAGCGATCCTCCCGCCTCA GCCTTCTGAGTAGCTGGGACTACAATTGGCCACAACCATGCCCAGTTTATTTAAAATTTT TTTTTTGTAGAGACAGGGCCATGCTGTGTTGCTCAGTCTGGTCTTGAACTCCTGGCTTCA AGTGATCTTCCCATCTCAGCCTCCCAAAGTGCTGGGATTACAGGTCTGAGCCATCACACC TGGCCTATCAGTTTTGTTATAACCCTCCTACTATCCTAGTGGGTTTGAAGTGGTACCTCA TTGTGGTTTTAATTTGTATATCCCTAACAGTGATGTTGAGCATCTTTGTACACGCTTATT GGCCATTTGTATATCTATAGTGAAATGTCTATTCAATGCCTGCCCATTTAAAAATTGTGT TATTTGGTTGAGTTGTAACAATTTTTTTTTCCTTGGGAGACAAGGTCTTGCTCTATGACT CCAGATGGAGTGCAGTGGTGCCATCACAGCTCAATATAGCCTTGACCTCCCGGGTTCAAG TGATCCTCCCACCTCAGCCTCCCCAGTAGCTAGGAGTATAGACATATGCTGCCACACCCG GCTAATTTTTAAATTTTTTGTAGAAACGGAGGGTTTTACTTTGTCATGCAGGCTAGTCTC AAACTCCTGTGCTCAAGCGATCCTTTCATCTTGGCCTCCCAAAGTGCTAGGATTACAGGC ATGAGCCAGTGCACCTGGCCAGTTGTAACAATTCTTTATATATTTTTGACACTATTTCTT TGTCAAGTATAGGATCTCCTACTCTGTGGCTTGTCTTTTTGTTTTCATAATTGTGTCTTT GAAGTGTGGAAGTATGTATGTATGTATGTGTATATTTATTTATTTATTTATTTATTTGAG ACAGAGTTTCGCTCTCGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTGCA ACCTCCGCTTCCTGGGTTCCACCGATTCTCGTACCTCAGCCTCCTGAGTAGCTGGGATTA CAGGAGCCTGCTATCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTTGCC ATGTTGGCCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCCACCTGCCTCGGCCTCCC AAAGTGCCAGGATTACAGGCGTGAGCCACCGTGCCCAGTCAGAAGTTTTTACTTTCAGCT CCATTCTCAATTTTCTCATTTTAGCTTATGCTTTTGTAGTTGTATCTAAGAACTCTTTGC CTAGCTCAAGGTCATGAAGATTTTTTTGTTTTCTTCTAGAAGTGTTATAATTTTAGCACT TACATTTAGGTCAATGGTTCATTTTGAATTACTTTTTATATATCCTATAAGGTAAGGATC TAAATAATTTTTTTGCATGTGGAGCTACAGTTGTCTCAGCAACGTTTGTTGAAAAGACTA TTGTATTAGTCCATTCTTGCATTGCTATAAAGAACTACCTGAGACTGGGTAATTTATGAA GAAAAGAGGTGTAATTGACTCACAGTTCTGCAGGCTGTATAGGAAGCATGGCTGCGGAGT CCTCAGGAAACTTAAAATCGTGGCAGAAGGCAAAGGGGAAGCAGGTACATCTTTCCATAG CAGAGCAGGAGAGAGAAAGAGAGAGAGAGAGAGAGAACAGGGAGGTGACACAGGTTTTCA GACAACCAGATCTCATGAGAACTGTCTGACAGGAACAGCAAGGGGGAAGTCTGCCCTCAT GGTTCAGTTACCTCCCACCAGCCCTTTCCTCCAACACTGGGGATTACAATTCGACATGAG ATTTGGGTGGGAACACAGAGCCAAACCATGTTAACTATGTTTTTCTCTACTGAGATCTTG GCACTTTTGTTAAAAATCAATTGACCAAGGCTGGGCGTGGTGGCTCATGCCTGTAATCCC AGCACTTTGGGAGGCTGAGGTGGGCGGATCAGCTGAGGTCGGGAGTTTAAGACCAGCCTG ACCAACATGGAGAAACCCTGTCTCTACTAAAAATACAGAATTAGCTGTGTGTGGTGGTGC ATGCCTGAAATCCCAGCTACTTGATACTCAAGGTTGAGGCAGGAGAATCACTTGAACCCA GGAGGCGGAGGTTGCGGTGAGCCAAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGA GTGAAACTCCGTCTCAAAAAAAAAAAAAAAAATTAATTGACCACTGGTGGCAAATTCAGA CTACTTAAAAAACAAAAAAACAAAAATCAATCGACCATAAATGTAAGAGTTTATTTCTGG ACTCTCACTGTCATTCTGTTGATCCATAAGTCAATCCTTATGCCAGTTCCACATTGTCTT TTTTTTTTTTTTTTTTTTGAGACACAGTCTTGCTCTGTCACCAAGGCTGGAGTGCAGTGG CGTGATCTCTGCTCACTGCAACCTCTGCCTCTCAGGTTCAAGCGATTTTCATACCTCAGC CTCCCCAGTAGCTGGGATTATAGGTGTGCACCACCACACCTAGCTAATTTTTGTATTTTT AGTAGAGGTGGGGTTTCACCATGTTGGCCAGGGTGGTCTCGAACTCCTGACCTCGAGTGA TCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTAAAGGCATGAGCCACTGCGCCTGGCC AGTTCCACATTGTTTTGATTACTATGGCATTATAGCAAGTTTGAAACTGGGTAATATAAG TATGTATGTATGTATGTATGTATGTATGTATTTATTTATTGAGACAGAGTCTTGCTCTGT TGTCCAGGCTGGAGTGCAGTGGCATCATCTTGGCTCGGCTCACTGAAACCTTCACCTCCC AGATTCAAGCGATTCTCCCACCTCAGCCTCCCGAGTAGCTTGGATTACGGGCATCTGCCA CCATGCCCGGCTGATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTGGCCAGGC TGGTCTCAATTCAAACTCCTGACCTCAGGTGATCCACCCACCTTGCCCCCCGCAAAGTGC TGGGATTAAGGCATGAGCCACCACGCCTGGCCTGGGTGGTGTAAGTCTTTTAACTTTTTT TTTCTTCTTCTTTTTTTAAATTATTTTCACTGTTCTGGGCCCTTTGCATTTCTGTATGAA TTTTAGGATCAGCTTGTCAATTTTTACAAAATAAAAAAAACCTTCTGGGATTCTGACAGG TATTGCATTGAGTATGAAATCATTTTCTGATGCATAAATTTTGCCATCTGTTGATGAGCA TCTGGCTCTGTTCTTTTTTCACTACATGGACAATGTCACTGTGAGCACGTTTGGTCACGT CTGCTGGTGCCCATGTAAAGCTTTTCTCTAGATAAGAGCCTATACCTAAGAGTAGAACTG CTCTGTGCCTCTTCAGCTTTTCCAGATAATGCTAAGTTATTTTCCATAGTAGCTGTGCCA GCATACGCTTGTAGTAGTATGTGGGCGTGTGAGAGTCTGTGCTATTCAACATTCTACCAC CATTTGGTATGAGCAGATTTTCTATTTTAATTTTTCCAGTCATATTTTCTTGTGGTTTTA ATTTGCAGTTCCTCGATTACTAATAAAAATGAGCATCTTTTCACATATTTATAGGCCTTT GGGGTTTCCTTTTCTGTAAAATGACCTTTGCTGATTTCTTTTGCCCATTTTTCCATTTTG TTATCTGTGTTTTTCGTACTGAGTTTTGCAATTTTTAAGATGTATTCTGGATAGTAATGG TCTACTTCTTTCCTTCCTACTCAGGTCATCTTTGAATGTATGCATTTGTTGTGGCTATTC AAATTTTTTTAACCTTTTTTCTGAGACAGATTCTTGCTCTGTCTTCCAGACTGGAGTGCA GTGGGGCGGTCTCGGCTCACTGCAACTTCTGCTTCCCTCGCTCAAGTGATTCTCCCACCT CAGCCTCCTGAGTAGTTAGGGCTACAGGCACACACCACCATGCCTGGATAATTTTTGTAT TTTTTGTAGAAACTGGGGTCTCACTACATTGCCCAAGCTGGTCTTAAACTCCTGGGCCCA GGCGATCTTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCC CAGCTGGGATTTGTATTGTTAACACATACCTGGGTTACCTGATTCTTATCAGACAAGTTT AGGAAGCGGCACCAAAGCTTTAAAAACTGTGGCATCTTCAAAACAGTAATTTAAAAAGTA ACTTCAATTTATAAGATCATTATAGCTTTAACTTTGGATTAAAAACAAAATCTTATTCCT GTTGTCCTTTATAAAATATATGTTCTATGAAACCAGCTTGGGAGAAAATCAATGCACAGA TGTTTGGGAAGCCCCAGCTGTGTTTAATTTGAAATCCTCTGTTTAAATTCTCTCTCTCTC ACCTCACCAGTGGGCAGTAACTCATCTCTGAGAGACTGTCCAAGCCCAGCTCTGGGTAGA ACTCAGAGATGTCACATCCCTAGGAACCGAGAACTGTGTATTGTAAACAGTCTCTGAGAT TTGGAGTTGTTAGCTTTTTCCAGCCTTGAAATCTCATGGGGGCAGCTGTTTAAGTTGGAA CTCTCACAAAGGGCATATGAAAATCGCAGAGCGAGGTGTCAGGAAATGGAATTCCACATA CATCCAGTTGCCACGTTTGGTGTCAGCACTATTGTTTTTACAGCTTACATTCCCGCCCCG CCCCCCCCCCCCCCCCCACAAATAACATTTGGGCTGTAAGGGGATGTTTCGCAAATCAGA CACGTTGTTTACTTTTAGGCCTGTAATGCTATGGAGAAACTTGGTGACTCTAACAATTTA GATGTTGGGTAACAACACCAAACTGAAAACACATGTCAACCTATCTCTTGACATGGTGAA CGTTCTCACCATTCTCTGCATATTGGAATTGCATATTAAATAATCCTTTCTAAATGTCTG AACATCTTTTTTTTAATTTTTAAATGACATTTTTCTTTCTGAGGGTCAACCATTGAGGTG ATGAAGTGTGGCAGTTATTTAATTCCTTATGCTGACTTTTGAATTTGTAAAGTCTTCAGG GCATGGCATTAAATTTAGTTCTTCAAAGTAGAAAGAGCTTTTCTGTTTCTGATGATAAAA GATAATCAAAGGTGTTTGGGGCCACATTGTGTGACTGCGGTCTTCCATTAAAAGTCCTGA ACGCTAAATAGCAGACGAGTACTCAAAAAAAGAGTTCTGAACATGTTGGCCGGGTGCAGT GGCTCATACCTGTATTTCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGGTCA GGAGTTCAAGACCAGCCTGAGCAACATAGTGAGAACCTGCCTCTACATAAAATTAAAGAA AAAAAATTAGCCAACCATGGTGGTACATACCTGTAGTCCCAGCTACTCGGGAGGCTGAGG CAGGAGGATTGCTTGAGCCCAGGAGTTCATTGCTGCAGTAAGCTATGATTGCACCAATGC ACTCCAGCCCGAGCGACAGAGCAAGACCTTATCTCTAATAAAATAATAATAAAATTTAAA AAAATTAAATAGTCCTGAACATGGCTGTGACCCTTTGGCATGAATGAGAATGTAGAATTC AGCAATTCCCCGCAAAGCTGAAATGTTTTCAGCATTGAAGGTCATATTTCCAGAGTAACA TGTATTCACTGAAGCTTATGTTCCTTTTGGGGGGAATTTGGGACTGAGTATAAATAATCA GTGTGAGTTTATGAAGCCTTGGGGATTTACTTATGGGGTCATTTCTTAGAAAAGAATGTT TAAGGATGCTGATCACCCTGAAATCAACAGAAGAAGCCAGTCTGCAAAGCAATTGAACAA AGATGGGGCCACAGATGAGGACTGTGATGAGAGAGATGTCATTCACTTCTCTCAGTGATT TTGAGTGCTTCCTGGTTCAGTATACAAGCAGGATCCTTTTGGATAAGGCTTTCCTGAAGA AGGTGATAGTGTATTTTCTTAAGAGACTGTTATGGGCCGGGTGCGGTGGCTCACGCCTGT AATTCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCACTTGAGGTTGGGAGTTTAAGGCC AACCTGGGCAACATAGCGAGACCCCATCTCTACAAAAAAAAAAAAGGAAGGGAAAACAAA GAAGAGGTTCTGTTGTAAGCAGAGTCCGGCTCTCTCTGTGAAAAGCACAGTGGTTTAGCT TGTCATTGTATGCTCAGCACCTCGCACAGGCCTTGGCACATAGTAAGTATCTCAACTTGT ATATAGAAACCATTAATTTTTCAGATCTGGAGTGTCCTACCCATACCAGACATGCCAGAG TGAATTTTCTCTTTTTTTCTCTTTTTTTAGTGTTCAAAGCTTCTTTCAGACACCAGTGTT ATTCAGTTCTACCCAAGCAAATTTGTCCTTATCACCGACATACTTGATACATTTGGTAAG TACCTGTCATATGCATCTTAGATCTAGGAAATGTGTTCGTTTTGTCAAGAATTGGGTGGT AGAGTTACTGTAAATTAGGTTCTGCTGTGGTTTAAGTTATTAAGTAAGTCATGGGAGAGA TCAAACCGTTCCCCCCCACGCCCATTAATAAGGGCGCTATTTTTGAAACATTCTAAAATT TCTAAAATTTTATTTTTTCTTCTTTTTTTTTTTGAGTCAGGGTCTTGCTCTGTTATCCAG ACTGGAGGGCAGTGGCGCAGTCATGGCTCACTGCAGCCTCAAACCCCTGGGCTCAAGCCG TCTTCCTGCCTCAGCCTCCTGAGTAGCTGGGGCTACAGGCTCATGCCACCGTGCCCAGCT AAGTTTTTTTTTTTTTTTTTGGTAGAGACAGAGTCTCGCAGTGTTGCCCAGGCTGCTCTC AAACTCCTAGCCTCAAGTGATCCTCCTGCCTTAGCCTCCCAAAGTGCTGGAATTACAGGC ATGAGCCACCATGCCTGGCCTGTTTTTCCTAATCTTGTGATAGACTAGTAAAGTGAATGA GTGAAGCAGGGCAGGCTGGGGGCACTAAGCAGCATGGGTCCCTTGCCGTCTCACAGGCAC CTGAAACTGAACTTGGCATCTGTTCCCAGCCCTTTCTCTTTTCCCACTGAGTTTCTGTCT CCAGGAATGGCACCACCATGTACCCAGTTGCCTGAGCTGGGAATCTGAGCATCTTCCCCC ACATGCCCATGTCCAGTCACCAGATTCTTCGGTTCAGCCTCCTAAAGCTCTCCCCAGCAT GTCTATTTTTTTCTTTCTTCACTGTTAAAATTTTTTTTTTTTTTTTTGGAGATAAAGTCT CTGTCACTCAGGCTAGAGTACAGTGGCGTGATGTTGGCTCACTGCAACCTCTGCCTCCGG GGTTCAAGTGATTCTCCTCCCTCAGCCTCACCAGTAGCTGGGATTACAGGCACGCACCAC CACGCCTAGCTAGTTTTTGTATTTTTAGTAGAGATGGGATTTCACCATGTTGGCTAGGCT GGTCTCAAACTCCTGACCTCAAGTGATCTGCCCTCCTCGGCCTCCCTAAGTGCTAGGATG ACAGGCATGAGCCACTGTGCCCAGCCTCACTGTTAAAATTTTAATCCTAGCCACAGTCCT CTCCCACCTGGATAGCTTCCTGCATCACTGTGGCTGCCCCTAGTCCCACACACCACCTCA CAGGTAGAGAGACCTTTTGGAGCCAGGTAGAAAGGTTTAGACTGAAGAGAATAACCTGGA GGAGCAGGAGGCCCCTGTGCTGCTTGGCAGTGGTTGGTTAGGCCAGAACATCGTGCCATT AGCAGTTTGCTCAAACCATGCAGCCCTCTAAGCTGTATATGATGTGCCCCACAGCAAGGC ACCCCACCAGAACCAGGAAATAGGGGCGCCTTCTGAGAGCTGAACACGTGGAAGATCAGA ACAGAGACATTCACTGTCTTACAGGGACTAATGGGCTCCCAACCCAGCAAATCTTATCTG TAAACCCATCGAAAGATACAATGTGTCAGAAAGCAGACTATCAATCTGAGAGACTCATTC ATTTCTGTGCATCCCAGTCCTGTCCAAGAGACCGGAGGCCTGAGTGCGCTAGCTAAAACA AGTGACAAGAAAGCTAACTAACCTTGAAAAAGTGGGTCTTTATTGGCTTATGCTGAAAAG TCCAGGGGTAGTTTGGCTTCAGGTGCAGCTGGATCCAGGAACCCAAACAGTGTCATTAAG ACCTTGCCCTTGGGCCGGGCATGGTGGCTCATCACACTTGTAATCCCAACACTTTGGGAG GCCGAGGTGGGTGGATCATCTGCAGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGA AACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTTGTGGTGCACACCTGTAGTC CCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGTTTGAACCCAGGAGGTGGAGATTGCAG TGGGCCAAGATCACGCCACTGCACTCCAGCCTGGGCGACAGGGCGAGACTCCGTCTCCAA AAAAAAAAAAGAAAAGAGAAAAAAAAAGACCTTGCCCTTGGTTGGGTGCATTCTCGAGCT TCACAAGCTGTCCTCAGCTTCTGCTAGCTTTATTGCTAGTGGTCCCAGGGCATGGAAAGA GCTACTTTCTCCAAGCATTCCCACAGAAGTTTCAGAATCCCATCTTATTGGCCTGGCTTG GATCACATGTCAGTCCCTGAGCCAGTTGTGTTATCTGGGGGATGAAATGCACTGATTATC CAGGCCTGGGTCACCCCAAAACTAAAAGAGTGATACAGTTAGCAGAAGAAAGGGGAGTGG ATGCTACCTGGGCAAAAAGAAGAGATGTCCCAGCTGACAGATGAGCCCTGATGGGTTCAG ATGGCCCGGAGAGGTGGTATCAGGCTCTCTGCAGGCCACTAGGGAGGTGTCAGCAAACAG AAGGGATAAAAATCCTTGCCTTGGCTAGGCACAGTGGCTCACGCCTATAATCCTACCACT TTTGGAGGCTGAGGTGGTTGGATCACTTCAGGTCAGGAGTGCGAGACCAGACTGGCTAAC ATGGTGAAACCCCATCTCTACTAAAAATATAAAAATTAGCCAGGCTTGGTGGCAGGCACC TGTAATTCCAGCTACTTGGGAGGATGAAGCAGGAGAATCGCTTGAACCCGGGAGGTGGAA GTTGCAGCGAGCTGAGATCGCGCTGCTGCACTCCAGCCTGTGCCACAGAGCTGAGATTTC GTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAGAGAAAAAAAATCCTCGCCTTTGTG GTGCTTATGTTTCCAAAAAAGAGAATTTACAAAACAATTAAGTCAACCCAATTGTATGTT AGACAATGATCCATGCTATGGAGAAAACCAGAGTGGGGTGAGGGGGTGAAGAGGAATGGA GGGAATTAGGTGAGGGGGTAGGGGTGCAAGTTTAAGTAAGGTGCTCAGAGGAAGCCTCGT TGAGAGGTTACCTGAGCAGGTGCTTGAAGGCGGTGAGAGGGGAGAGGTGAGCCCTCTGGG TCTGTGGGGTGGAGGCCAGGGGCAGAAGAGGCCAAGGAACAGCTTGTGCGGAGATCCTGG GGTGGGAGCATTGGGAGCATGCCAGGCTGGCCTGAGAACCAAGGAGGCCAAGAGAGAGGC GATGAGATGAGCCCGGGAGAGGGGCAGAAACTGACATGGTCAGAGATCATGGTGGCCTTG GGGGCCACTGGGAGGACTTGGGCTTTGACTCTGACTCTGAGGACAGGAGGGGCCACCAGA GGGTGTTGAGCAGAGGAGGGAGGTGATCCCACGTGGGATTTAACAGGCTCCGTGTTGAGA CTAGACTGTAGGGCGGGGGTAGAGCCCGGAGCCTGTGGCAGCACTTGCGGTGAGAGGCAG GGGTGGCTTGGCCCCGGGAGGCGGTGGAGATGGTGAGGAGAGACCCAGGATGGATGAGGG CTTTAGGTTCTCAGGTTAGATGTCAAATCATACACTGCTGGTCCTTGACGTGTCCATGCA CACAGCTTACCTTCGGCGAGTGTGAGGCCCTCATTGGTGGGGAGAGGCTGGTGGCTGTGT CTGGCTCCCCTGGCAGTCTCATTCCTCCCGTGAATTAACCTCTTGGCCGTCTGGTTCCCT CGCCCGCCTCTCCTAAGTTTCTTTTGTATGAGTCAGCTTTCCTGAGCAAGATTAACTCTG AGACACTGATTAGCTCTATCCTGCAAGCCTGGCCAGACCCAGACAGCTCACTCACCTTGC AAGAACTCTGGGCAGCCACTCTGCCAGCTCCTGCCAGCAGCACTCCAGCCCCGTCCTGTA CTCCCCGGGCTGTAGTGCAGATGCTGCTGTCCTTGTTGCGTCCCAGAAAACAGCTGGGCT GGGAGTTGGGAACAGCAGTGGTAAACCTTCAACAGATGATGACCTTGGACAGACTGTTTA GGTGCTTTATAGATATTAAGTCCCGGCCAGGCGCAGTGGTTCATGCCTGTAATCCCAGCA CTTTGGGAGACCAAGGTGGGTGGACCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAAT ATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGTGGGCACC TGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGGAGAAAAAAAAAGATATTAAGTCCCATA ATCTGCATAACAGCCCTATGAGATGGGTCTGGTTGTTGTCCCCATTTTATAGATGAGGAA CCTGAGGCTTGGAGAAGGAAAGTAGCTTGCCCAGGGTCACCATCATAGTGAATTGCAGAG CTGAGGCTCAACTAGCTCTCTGCAGTCAAAGCACCTACTTTATTTCTCTTTATACATTGC TTATGGGGGAATGCATATACCATTTTTTTTTTTGAGACAGGGTCTCACTTCATTGCCCAG GCCACAGTGCAATGGGGTGATCATGGCTCACTGCAGCCTTGATCTCCTTGACCCAAAGGA TCCTCTTGTCTCAGTCTCCCAAGTAACTGGGACCACAGGTGTGTGCCACCATGCCCAGCG AATTTTTTTTTTTTTTTTAGCAATGGGATCTCACTGTGTGGCCCAAGCTGGTCTCAAACT CCTGGAGTCAAGCCATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTATAGGCATGAG TCACTGCACCTGGCCTAAATGCATGTACATTTAACCCAACAGTTTCACCTCTGGGAATCT ATCCCACCTGTAATAGCAAACTATAAGAAGCAACTCAAGTGGCCATCAATAGGAGCTAGC TCAATAAATTATGGTGTGTCTGTATAGTGGAGTACTAGTGGCTCTGTGAAATGAAAAGGC TGGGCATGGTGGCTCACACTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCA CTTTGAGCTTAGGAATTCGAGACCAGCCTGGGCAACATGGTGAAACCCGTCTTTACTAAA AATACAAAAATTAGCTGTGCGAGGTGGTACGCGCCTGTAATCCCAGCTACTCGGGAGGCT TAGGTGGGGGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAACTGAGATCAAGCCA CTGCACTCCATTCTGGGTGATAAAGTGAGACTCTATCTCAGAAAAACAATCAAACCAACA ACAACAACAACAAAACAACAACAAAGAAGGGAAGGAAAGGGCTGGGCATGGTGACTCACA CCTGTAATCCCATAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATAACTTGAGTCCA GGAGTTCAAGACCATCCTGGGCAGCATAGCAAAACCCCATCTCTACAAAACATTTAAAAA AAATAGCTAGGTTTGGTGGTACAAGCCTATAGTCCCAGCTACTTAGGAGGCAGAGGCAGG CAGATTCCTTGAGCCCAAGAAGTTTGAGACTGCAGTGAGCTATGATGGTACCACTGCACC CTAGCAAAAGTAAGACCCTGTCTCAAAAAGAAGAAAAAAAAAAAAAGAAAGGAGGAAAAT GTAGACTACATGTTGGTATTCACTTGTGTCTCCCTAAGGAGACATTAAAATGATAGCCAA GAAACCGATAGAAATGGTTTCTCTCAGAGGGTGTGCAGGGCAGTGAGGTGGATGGGATGG GCCAGGAGAGAAACTGCGCTCGGTACCTTCTGCAGCTTTTTTGAATTTTGAACCAAGGGA ATGTTTTACCTATTCAAAACCAAACATTCACACAGAGTAGCTGCTTTCAGCACTTCCCAA GGTCCCTGTCCTTCCTCTCCACTTCAGAATGGTGTTCCCACGGTGCTGTTGTTTAAGTCT ATTGTGAATAATATTCCTCAGGACTGTTGAGGCAGCCTGCATGGACAGATGCTCAAAGAG TCTTTATTAAGGTTTGGGGCTAATGAGTGTTCACTTTATAAAAAAGGAGTGAAACCCTGA CTTGCTTGGTGGAAATGTGGAGTCCTGAGCTCCATTTTTCTGCACATGGTCATTACTCTG CTCTAAAAGAAGATGCATGACAGTATAGGGACAGGTGTTTCATGGTTGTTGACATCATTG ACAAGAGGGTCAGAGCATCTTGCTGTGCCAGGGATGCAGGCTAAGGCCCCAGCATCCACA GAGACTGGCATGCACAGTGGGAAGACGTGTGCCTGGTTTCTGCTGGGATTTCACTGGAGG CATTGGGTACAGAGGTGGGCTTCTGGCTTCAGTGCCTGCGTCTCCTGTTTCAGGGTTGTG TGAACTTGAGCCTCAGTTTCTCCACCTGTAGAATGGGGCTATCGTAGACCCTGCCTCTAA GGGTTTCTGGAGAGGATTAAATGAGAGGATTCATAGGAAGTATAATGTCTTTCCTTTTCT AAGAGCTTGCTGGCAGGATTAAAGTAAATGACCTTGAATAGTGCTTGGCACAAAGTAAGT GCTCAGAAAATGCTAGCTGTTACCACTGTTATTATTTATCTCTTTTAGTGTCTTTGATTT GTAAGAAAGCAAATCAAGACAGGAAATAAATCTAGGATCAAGTGTTATTTCTCAAAATAG TTGTCTACTAGCTTAATAGACAAATCACTTTTTTCAGTAAAACTAATTTTGTAGTTAAAA GATCCTTAAAATATGAAAGTGAGGCCCAGTACAGTGGCTCATATCTGTAATCCCAGCACT TTGGGAAGCCAGTGCAGAAGGATTGCTTGAGCCCAGGAGTTCAAGACCAGCCTGAGCAAT ATGGTGAGACCTCGTCTCTACGAAAAATTTAAAAGTTAGCCAGGCAAGGTGGTGTGCGCC TGTGGTCCCAGCTACTCAGGAGGCAGAGGTGGGAGGAGCCCCTGAGCCCAGGAAGTTGAG GCTGCAGTGAGCTGTGATTGCTCCACTGCACTCCAGCCTGGGTGACAGAGCAAGATTCTG TCTCTTAAAAAAAAAAAAGTGAAAAAGAATGTGGAGATGAAATTTTTTTTAAAAAAAAGA AAGCTAGTTTTAGAGGGATGGCAACTTTCGTGTAGGAAATAAAGGTGTTTTGTGCTGGGT TCATTCTGTGCACCATGGGAGGTGAGAAGTTATGCAGCCACCTAGTGTGGTTTGCTGTGT GATGGTCCGAGGTAACATTGCATGCATCCCTAATGCCAGGGTTCTGGGGTCATCACAAGG GAGGCCTCTCTCTACACGAGGTGTGGCGCTATAGGGAACCCAGAGCCGCTGATAAGGAAA GCTCGTTCTGCCAGGAGGAAAAAGGCAGGTGGCTTTGAGAACTGGGGCTTGTTCTCTAAG GCCTTCCAGGGGCTTCTAAATGGAGCCAGTGGTTTGGAGCAGTGCTTCTCATACTCAGCT GCACATTGAAATCACCTGGGCAGCTTTACAAACACCCACAAAGTCCCAGCTGCATCCAGA CCATTTAGAAGAGGACCTCTGAGGATGGACACAGACATCCACATATTTTCAATAGTCCCA GGTGCTTGGAGTCTGCAGCCCAGTTGGAGAAGCACTGGCTCAGAGGGAAAAGGGAAGTTT GTTGCTATTTCTGTAGATTCCAGAGGCAAGGCAAGTTTTAGCTCAGAGACCCACTGGTGT CTGCCTAAATCAGTGGTTCTCACATTTCAGCATGTATAAGGATTTCCCAGCAAGGTTATT CAGAAATCCATATTCCTAGTCCTCATCCTCCAAAATACTTTTTTTTTTTTTTTAAAGACA GTGTCTCACTCTGTTGCCCCAGGCTGGAGTGCAGCGGCACAATCATAGCTTCTATCTCTG CCTCTCAAGTAGCTGGGACTACACGCGTGCACCACCACGCCTGGCTATAAAATATTCTTT TCCAGTAGCTCTAAGGTGGGCACCAGGAATCTGCATTTTCAACAAGTGCCTTCAGGAAAT TTTAATGTAGGTGGTCCAAGGCCAGGTGTGGTGGCTCACACCTATAATCCCAGCACTCTG GGAGGCTAAGGCAAGCAGATCACTTGAGCCCAGGAGTTCAAGACCTGCTTGGGCTGGGAA TATAGGGAAATCCCATCTCTACAAAAAAATAATTAGCCAAGCATGGCAGCGCATACCTGT GGTCCCAGCTACATAGGAGGCTGAGGTGGAAGGATTGCTTGAACCCAGGAGGTGGAGGCC GTAGTGAGCTGTGATCACGCCACTGCACTGCAGCCTGGTGCCAGAGTGAGACCCTGTCTA AGTGAATGAAGGAATGAATGTAGATAGGAAGGTATTTAGGTAGGTGGCTCATACTAGGAG AAGCACCTGGGTGGAACCTCTTAGCTTGGCTGGCTTCCTTCACTTAATCCTGCCTGATCC CACGTTCTTTAACCTGAAATGATCTTTGTATTTTCCTGTCTCTTTTTCCATGTATGGACA AGCTGTGTTGTTCTTTATTGCCCTGAATAAAGGGTTATGAAAAAAAAAAAAAAATCTCAT AGAGGGAAATACTTTCACATTGAAGGTGACTTAGGAGAGCTTAGAAAATGAATAAGGACT CTAATTTTTTACTTCCACATATTGATAACATTTTGAAAATACATGCACAGAATAAATAAA ACTTTTGATACCAGTTTAGGGGTCCAGGCTGCCTACCTGTTGTGTAGAGTTTTATTGGAA CGCAGCCACATCAATTTGTTTGCACATTGTGGCCACTTTTATGCTACAGTGGCAAAGATG AGTCGTCAGGAAAGTGACCCATGACCTACAAAACCTCTAGTATGTTCATCCATCCAACAA ATATTGAGTACCCCCTGTGTGCCAGGCACTGATCAGTACTAGGAATATGTCAGTGAACAA AACAAGCACAAATCTCTGCCTTTGTGGAGCTTGCATTCTAGTTGAATCTCAAATTCTGAG GCTTCTAGGGACCAGGCAGGTCACATAAAAGAGTGAAAAGCACGCTGATGATGAGAGACA GTAGGGGGTGGTTGAGACTGGCAAACTGGTTAGTGTATATGCCATTTCAAGGGGCAGCTA CTAATTTGCTCTAGCTGTGTTATCCTATAGAGATATCGCCACATTTTTGACATATTTTAT GTGAAGAAGGAGAAAATATGGCATGTGAGTTCTCCCAAGTTGTAGAGTTTGTTTTAGTTT TTGTGTTTGAGACAGGGTCTTGCTCTCTCACCCAGGCTGGAGGGCAGTGGGTGATCATGG CTCACCGCAGCCTTGAACTCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTCCCAAGTAG CTGAAACTACAGGCGTGCACTGCCATGCCTGGCTAATTTTTAAATTTTTTGTACATACCC TGTCTCACAGTGTTGCCCAGGCTGCTCTTGAACTCCTGGGCTCAAGCAGTCTTCCTGCCT CGGCTTCCCAAAGTGCTAGGATTACAGGTGTGAGCCACTATGCCCAGCCTCTTCCAGTTT TTACGTGTTGGTAACCAATTCAAAAAATGTTAAAACACTTTGTGGGCTGTTGTGTGTTGT GGAGTGGCCATGCACAACTGGTCACAGGCTGGATTCAGCCCGTGGGCTGCCTGTTTTCAC CTCTGGCCTAGCATGGAGTGTGGACCATCGTCTGAGTGGATGGAGATACTTGAGACTCCT TTAGATTCCAAAGGGTAAAACGATCACTTTTCTGCCTTTCAAAGAAAGTAAAAGTCTACT GGAAAAACTAAAAACAAAACAAAAAAAATGTGGCTTAAAATCTGTCCCACCAGGTGGCAG CATACCATCACAAGTTAAAGCCTGTCTGGGCGATGATAGCTCTGGGTCCCTAATTAACAA ACATTTATTTACTGTTTGCTCCTGAAGAGTGTGATACTAACACCATCTGTCCTTTTCCTC CCAGGAAAGCTCGTGTACGAGCGCATCTTTTCCATGTGTGTGGATAGCCGCAGCGTCTTA CCAGGTAATGTCGCAGCTGTTCCTGGGGTGTCATTCTGCCCTGGAGTCAGGACTAGAAGG CTTTTATTGAGTCAGGATTCATTGAAGCTTGATAAAGGTTTTAATTTTGGGTGTGTTAAA GTAAAAGAAACACCTTTGAAGATTTCTGATCACCTCAGTCTTCTAAAAACATTAGAAGGT TTCTAAATGGCCCGTGTAGGAACTCAGGCAAGTCATTTGAATCTGCAAAGGCCTCACAGT TAGATTCAGCCAAACTTTCACACGAACATATTTTCCTCTGCTGCTTGACTTTAATATTTT TCCTATGTATCGTTCCCTCCTAAGAAGCAACTTGCTTGGAAAAAAAAATCAAAAACGACT TTATGCATATTAAAGAATGATGTCAAATAGATCAATAGTAATTGATGCTTTGAATTCACA ATCTATACCCAAATGATTTTGCATTAAATTGACTGTCAATCAAGTTTAAATTCCCAGGAG GTTATAATGGGACAAGTGGATGATGAATTTCTTTTGTCGTATAAATGGTAAGAATGATGT GTCTGGCAATGCAGGACTCTCAGCTGCAGCATCCTTTGCCTTTATTCCTCTTTTTAACTT CCGAGCACTGCTATGAGGAAACGTTCTCATCCGTCCAAGCTAGAGCAACCAGCTTGCTCC ATTGCCGCTCCACTTCCCTCCGCTCCTGCAGTGGGGCTTCCCAGGAGGTGAATAGAAAGT GTTTGTGACAGTAACCTATAACCTGACCTATATTCTTCCTTCTTTCCTCTTTCCTTTATT CCTCCCTCTCTCTCCTCCTCTCTCTTCCTCTCCCTCCTCCTCTCCCACCCTCTCCTTTTC TCTCTCCTTCTGCTTCCTATCTGTCCATCAATCGATCAATTTATCTTTATTTAATTTTTT TGAGATGGACTCTTGCTCTGTCACCCAGGCTGCAGGGCAGTGGCACAATCTTGGCTCGCT GCAGCCTTCGCCTCCCGGATTCAAGCGATTCTCCTGCTTCACCCTCCTCAGTAGCTGGGA CTACTGGTGCCTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTG TACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATTCATCCGCCTCGGCC TCCCAAAGTGCTGGGATTATAGGCATGAGCAACCGTGCCCGTCCCTTTTTTTTTTTTCTA TTTAATATTTTTACTTTTTCATCTTTGTAGACACGGGGTCTCCCTATGTTGCCCAAGCTG CTCTCAAACTTCTGGGCCCAAGCAGTCCTCCCACCTCAGCCTCCCAAAGTGCTGGGATTA TAGGCATGAGCCACTGTGCTTGGCCTGTCTTTTTAATACTATTTAATGTGCACATTTGTC AGAAAGAAAGAGACAGAACTCAACAGGCTTTTAGGATTTTTAGCTCTTGAAGGCTTTTTA GGTCTTGAAGTGCTTTTAGGACCCATCTTGTTTCATCAGAGATGGGCAGACCCAGTACGG AAGAGTCTTGCCCAGGGCCCTGCCACCAGCTACTGAGAGCCTTGCTCTTTCTTAGTGCTG CATCTACATTGTCCAGTACAGCAGCCACTGGCCACGTGTTGCTCTTGAGCACTTGAGATG TGGCCAGTCCAAATTGAGATGTGACGTAACTATTAAAAAAGACACCGGATTTCAAAGAGT CAGTACAAGTAAAAGACGGTAAAGTAGCTCACTAATAGTGTTTATGTTGATTACATGTTG AAACGGTATTCTGGATGAATCGGGTAAAGTACATGATTAAAATTAATTTCCCCAGTTTTT GACCTTTTTAATGTGGCTCATGTGGTTTTTCTTTGGGACCCTCCACGCCACTGCGTCACA CCTGTGACGATGTTTTTTCAGCAGCTCCTCCTATGTTCTGGCCATCTCAGGGTTGGAGGC AGTGATCTGGGAGAGGCAGGCAGAGGCCAGCCCAAGTGGAAAGGAAAGGCCTTCTCCGCT GGCTTGAGGATTTGGGAAATCTGAATTGTTTATTTATTTATTTATTTTTGAGATGGAGTT TCACTCTTGTTGCCCAGGCTGGAGGGCAATGACGCAATCTCAGCTCACTGCAACCTCCGC CTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTG CACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGC CAGGCTGGTCTTCAACTCCTGACCTCAGGTGATCCACCCACCTTGGCCTCCCAAAGTGCT GGTATTACAGGCATGAGCCACCACGCCCGGCCGAATCCATTTATTTAATATACACTTGCC AGCATGTAGCATGCTATACCATTGGCAGCAAACTTGAGCCAACAGGTGGAACTGAACCAA AATAGGTTTTTTTTTTTTTTTGGCAACAACAGCATTTAAAAAAAAATGACTTTTGATACA GGCTCTAGTTCTTCCTATTGTTATATACCCAACCTCTTAAAAATTTTCATATTTACCTGC CTGGCCCCCAGAAGCATTTGAATTTGCCTCTACTGCAATAATCTTCCTTTCTCCCAGTCT TCAGTGACTATACAAACAACATTTTAGGGCCAATTAAGGAAAAATTACTAATAACTAACT CCTTGCCTAAACTTAAAAGTTCAAAACAACAGATCAGTCCTCGTTTAGATACATTAATTA TAGCACTTTTATCACTAAAATTCTTCCCTCTCCAAATAACTATTTTTGATCTTGAGCAAA GCAAATGATTTGGTTTTTTTTTCTTTAAATGATATCATTGTTTGTTTTCCTTTTAGCTAA AATCTTCATCTGCTTGTGTTAGCTCCAGTTCCAAGAACCTGAAAAGAACAGTAGATTATG TTTTTCAAAGTTGTTGGTGATCTGAGGAATGACTCTTAAGTATAATTATCATGAAAGCTT TAGAAATCTCCTGTGCAGAATTCTGCCCAAAGAGATTATGTGTGAAGAGAAATTTGGTGG CATTTGTACTCATTCTTTCCATTTAAATCAAGTTCTGTTGGGTGAATTTCATACTTGAGC CCTTTGCCTTCAGGAATTTTAACTAAGGTATAGCTCTTCGGAGTTGAGAAAGATACAGTG TCTTTTGGGTTCATGAAAATCACACACTATTAGATGTGGTCATTTTTTCCCAACAGTTCT TAATCCAGCTTATGCATAAAGAGACCATCGACTCTGAGAAGTCAAATCATTTTATTTCCA GCTTGGGAGAGATAATTTGGGTTTATTGTATTATGGTTCCCATCACCATCTTCTCAGCAT TCCCATCTTCAGTTTTCCCCTGTGGCTGATGTGGGCCACATCGGGATAAGCAGTGGCCTT AACTGACCTGGCCTTTCCAGCACATGCTAACTAAGATGGTGCCAATCCCTATAACACTGT TACGTAAAGAGACCTCTCGCTGCTAGGGTAGAGACTTGGCAAATAAATGAAAGAACTAGA CTCATTGGTCTCCTGCCTTCTCTTAAAATACCCACAGAAGTTCAGGTTTGAAAAAAAGCA GCACCATAAAAGAAAAATAAGTGGGAGCTAGAAAAAAAATCTCTGTTCTTTGTTATATTG AAGTGTCTTCTGAATTAATTTCCAGATTTTGAAGGAGTCCCCATGTAGCAGCCCAAGTGC TGAAGTCTAAACTGTGTCATGTCATTGCCATTCCTGTGCCCAGAACCCTTCAGGGGGTTT CCATTATGTTTAGAAAAACTCTCAAACTCCTCACCAAGGCTTCAGCCCTGTATGAACTGG CTTGTCATGCTGGCTGCTCCCCTTTCTGCTCAGCAAATTGGCTTGCTTTTTGTTCTTTGA CCATAGTGAGGTTATACCTACCTCAGGGCCTTGCACTTGCTGTTTTCTTTCCCTGGAATA TGTTTCTTCCACATCTAGGCATGGCTGGCTCCCTTTCGTAGTTCAGGGCTCAGCTCAAAT GCTGCCTCTGTGGGAGCCTTCTCTGACCACTACATCTAATGAGCCCCTTCCCCTAAATCA CACTCAAGTCACTCTTTATTCCAATACCTAGTTTAGTATCTTTAATAGTACTTACTGCTG TTAGATATTATCTTATTTGTTTGCCTGCTTATTCTCTTTCCTGTTTAGCATTTGTCTCAC CCCACTGGAATGTAAGTTTCATGAAGATAGGATCTACCTTGTGCACTGTTATCTCCCCAA AGCCTGGAACACCACCTTTAGTTGGCCCTTAAGGCATTTGTGTTGAGCACATGAAGTAAA GGAATATAATATTTAGTTTGCTGTAAGATTTTAAAGTCCCACGTAACATAATCCTTTTCC TAAATTATCTCTTGAGCTGGAAGGAAAGCCTAAAGATTCTGTATTGGTGTATGCAGATTG TCGTATAGCTTGTAGTCAATGCGTGTATGCAAGGCAGCCTGCCTTTAGCCTGATTTCCAA CTCTTTCAGGCAACCTGAACCAGTTTGTTTTAGCCATTGCTGAATCTCAGTTCCTTCAGC TAGACAGTGAGAGATTTTGTAGATGACCTCAGAGACCTATTTTTGCTTTTGGATTTTAAG CCACAAGATTCAGTCATATGAAGGGAAATTAACACTGCTCTTCCCTCTCCCCAAAGAGAA GATTGACAAATGAATGTAAGAATAACTGCTATCTTTTCCTGTCTGGATCTCTTGAAAGTA GAAAAAAAAGTTACTTCATGTGTAGAGATCTAGGCTGGAAAGGGGAAAATGGTCATTTCC CATCCTTTTGAAAATGGTAAGCAAATAGTTCTCAAGTGAATGAAGCATGCCAGACATCCA AAAATAGAGTGAGGAGATTGCAATTTCAAAATATCTGCAGTGATTAGTGACTGTTCTCTG CTAGAGAAGTACCTAGAGGTTTATCTTTTTTTGCTGATTCTATGGGAATTTTGATCACCT TCATATACTACCAAATGACAGAATCAGGGATGAAAATGACTCATTGCAAAACAGGATGAA AGCCAACAAGCTAAGAATCATTTGCTATATTCTAAAGTAACTAACTTCTCCCTTTTAATT TATTTATTCATTTTTTAGAGAATAAATAAATAAGGTCTTGCTCTGTCTTACTCTGTCTCG CTCTGCCCAGGCTGGAGTGCAGTGGCTCAATCATAGCTCACTGCAGCCTCAAACTCCTGG GCTCTATTGATCCTGCCACCTCAGCCTTCCAAGTAGCTGGGGCTACAGGCATGAGCCACT GTGCCTGGCCAGCTTCTCCCTTTTTGAATTAATCCTAAAAGTATAAAACATCCAGTGGTG GGATGGAGCTCTAATCTTTGCTGAAATCATTTCCATGTGAGAGGTTAACAAAGGCCTTCA TGGTGTTTGTAAGTTTTGTGTTTTTTCTTTCATTTCTCCATATTCTCTTCCATTCCTTAA GATGTATGTCAAGTCCAGAACTGTGAGAAATAAATTTCTGCTGTTTAAAAATATGTATGT CAAAATCAAGCTTGGGTACCAGTTCCAGAAAACTCAAAATAACAGTAATGAAGGTCAGGG CCGATGGGCCAGCTAGCCCCTGGTACCAAGGATCCTCACTTCTGTCTTGTTGCTCTCATG GTCAGTATGGCTGCAGAGGTTCCAGCTGTCATGTCTGCATTCCAGTCAGTGAGCAGAAAG AAGAAGTGAGGGAAGGCAAGCCCCTTTCCTTAAAGATACTTCTCAGAAGTTGCCCTTCTA TTTATATATCCTGGGACCAGAACTTGACCCACGTGACCACACCTAGCTGCAAGGATGGCC CTGTGTCCTGCAGGAAAATGCGAGTTCTTTTATTAAAGAGGAAGAGAATAGCTAATGGAG TAAACTGGCAGTTTCACAAGATGACTCTCTTGGAGCCAGTCGTGAGCCGGCAACATAATT CTGGCTGGTTTCTCACCTCAGAGGCCTTGTTTTACCTTCCTCTGGCCCATTGTGATGTGT AGAGCAAAAGCTTAGATCACATTTCATGTTGCAGTCGCAGGTCCGTAAAGCATCTGGAAT TCTCAACAATGTTGTCATAGTGACTGGTAGGTAACCAAGAACCTCTGGATTATATTAGAG GCAGTGGCTAAGAATGTCGGCCGCAGGGCCAGAGTGCCTGGGTTGAATTCTAACTCTTAC ATTTGCTTGCTGTGTGCCTTGGGTGAGTCACTACATTCCTCTGTGCCTTGGTCTCTGCAT CTGTAAAATAAGATAATAAAACTACGTACCTCAGAGGGTTGCTATATGGGATCAGGTGAG CTGTCTGTAAAGCACTGCGAACGACACTTGGCACTTAGAAAGCCTGTGTCTGTGTAAACT ATTGTTATCATCAGTTACTTCCTAATAGTGATATTTGGAAGGAAAGAAACAGGCTGAGTC ACCCCCTTTTCTGCTCCAGGGTAATGTATTCCCATCCAGGGACTCACACAGATCCTGAGA TTTAGGAGGGCTGATGGATCTTGTTTTTTGTATTACAGATCACTTTTCTCCAGAGAATGC AAATGACACGGCCAAGGAAACATGCCTAAATTGGTTTTTCAAGATTGCCTCCATCAGGGA ACTCATTCCAAGATTGTATCCTTTTTTTTTTTTTTGGTCTGATGATTTTAAAGATAGGCT AAAAGAATTGTACTGTTAATAGAAGCCATGTGATGGGATGCCCTGACATTCTTATTGAAA GTTTGGTCCCGTTACGGTTGCTAGCCTGAAAACACATACAGGGCAAGCCACATTGTAGAA ACCCTTGGACTCTTGCTCTTTCCAGTTTTTTGTCTTTTACTTTGAATACGATGCCATGTG TCAAGCATTTGTTTCCTTGAGGAACATTCCCACCTTAATTCTCTCAATTAAAATGCTTCA TATTTGTGTTTTCTCTGATTCCAAGAACTTGAAAGAACAGGGTCAAGCTTTGCAGGGCAA ATGCTACTATTGAAGAACAGATAATTTGACTTATACATAAATTCCATCTTAGTTACCTAA AGTTCTTTCTTTCCCCATAAAGCATTGATTAGAAATGCTCAAAACCCAGTTTATATTTCA GCATGCAACTATGAATCAACGTATAACATTTCCCACAATTTATTTCAAATAAGTATGAAA CTTTGAAAACCATATGTAGAAACCATAAGCTACCTTAGTTCGCTGGATTGTTGAGGGCCA CTGTGGTCCCCATCTCCTAAGACCCGCCTACTTCTATTCATGGATAGTTTAGTCTTTTCT CCATAGGGAGTAGACCTTCTGGAAAACATCTTCCTTAACAGGATGTTTTTGTAGTTACGT GGAGGCATCCATCCTGAAATGTAACAAATTCCTCTCCAAAACGTAAGGCTCTTCGGTAAA ATCTAGAACCATAAAATTTCTAAAAATCTCCCATGTGTACACAGATAGTAATGGCAATGT AATAGTAGCCATTATTCACTGAGTACTTAATGTGTGTTAAGCACCTTCTGTTCTTTTTCT CATTGAATCCAAATGAAAACTGAATGAAGTAGAGACACCATCCTAATCCCCATATTAGAG AGAGGAAAACTCAAGCCTGGAGAAGTTGGTTAAGGAGGTCATGGAAGATCAGCTCAACTG GATTTGAATCTTGGCTGTACTGGTACTAGCTGTATGGTCTTGAACAAGTTACTTACAGCC TCAGAACCTCTGGCTCCCTCTCCTGGGAACATGACCCTAAGAAGAGGTCTGAGGGGGTCC TTTGGGTCACACATGCAACAATGAGAGTCACCCCTGGCACACGGTGGGCCCATCCTCCAT GTTGGCTGCTGTTGATGATGATGATGATGAAAATGACGTCAGAAGCAGAAGCCTTTGCCC TTAGTGGCTTAGGTCCATGCCACTCAATTTATCACAATGTTTTGAGAGTAGTTACAGGAC GTGGGGGACCCAGATCTGCTTTCTGCAGAGCAGGTGAAATGCTGAGTCATGTTAGATAGC TAGATAATAAATTCCTTGAAGCCCGGGAGTGACTGATTCATGGTGCTCCACAGATAGCTC TACCGATTGGATTTAGAATTTATCTCAAGTGTGTTGGATTTGGATCTAGGGTTGCCTGGA ATAGTTTGGGGGAATAACATGGGGGCTGAAGAAACATTATTTTGCCTCACCAGTTGGAGG AGGATAATGCCTTAGGCAGAGGGAAGACATACGTTGCAGGAGAAATAAATTGTAATTCAC ATTGTTGGTGGTTGGAGGATGTCAGATGCCAGCCTGAGATTCACGGAAGGAACAGGGTAC GGGACAGTAAATCTGTGGCAAACGAAAATACATGTGGAGAGAAGATCAAGGGGTGCCCAG TCGATGGAAAATAATTGAAGACAAAAACTGTTAAAATTAATAAAATAAATGTGACCTCGA CTGGGGAAAAAATGTGGTTAGCCTCCACCACTGAGCAAATGATAACGATGAAAGAAATCA TTCAATGAATGAATTGTATCAGAAGAGAAAGACTGTTGTTACATTGCCTTAGAAAACTGA AACTTTGACCTTGGTTTGTTACTGAAACTTGATTTTTCCCCCCCTCCCTGAAATTTAGGA AGTCTTTATCTTTATTTAAAAAATTAAAGAACAGCGAGTTCTCACGTCGAATATAATGCT GGCCTGTTTTTGTCTCTTGCAGGGGAATTTCAGAGTGCCTGCCCCGGTTGACATGCATGA TCAGAGGGATCGGAGACCCACTAGTGTCGGTGTATGCCCGTGCCTACCTGTGCCGGGTAG GCCATGCGAGTCACTGCCCTTGACGGCACGGCTGCCACCCGTCTCCTTGAATGTTCACAC AGGGCCCTCCTTCCCCACCACCCCGCAAGTCATTGAGAGAAGGACTTTATTAGTGGCTAA TTTTAGATCATGGCTCTGCCACAGAAAGTAGAACTGTAGGGTTTCTTTTAAAAATTAATT TTAAAGTAGACCAACTTACTGTAGCTCTAATTAGGGGACGTTTAAGGTCATCTTCTTACA AATGAACTGGTTTTCAGAAGTAATTGTTTCTCAGTTCTTGCTGGGAAGGAGGTTCCCAGG GCCTTTGGGCTAACAGGTTGCTTTTCATTGACTTCAAACATGCTCTTCCTTTGTCTTGAC TTTGATTGCTTTATTAGTTTTCTGCTTGGCAGGGGAGCAGTGTCCCACATGATGGCAGGC CTCAGGGTCTGTGTGGCCTGGCTTAGGTGGCTGCTGTGAAAGGGGGTAGAGGGACTGATT AGAAATTACTTGCCCATGCCCTGCTTTAAAGCACCGTGAGGCTTCAGCTAAGCTATTAAG TTTTTTGTGTATGGAAAAAATGTAACCAATGGAGGTTATATGGTCTTTCTTTTTTTTGGA GATGGAGTCTTACTGTGTCGCCCAGGCTGGAGTGCAGTGGCGCCATCTCGGCTCATTTCA ACCTCCACCGCCTGGGTTCAAATGATTCTCCTGTCTCAGCCTCCTGGGTAGCTGAGATTA CAGGTGTCCGCCACCATGCCCGTCTAAGTTTTGTATATTTAGTAGAGATGGGGTTTCACC ATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCCACGTTGGCCTCCC AAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCAGTATATGGTCTCTCCATAG TTTTCTTCAGCTCACACAGGGGCTTTGCCTCTGTCAGGACTCCCCCTAGCAACGAGAATC TTCCCTATCGTCCCATCAGTATTGCACATCCTTAGAGAGGGATCATTGCACCTGATAAGC CCCAGACTTCCTTGAGGACAAAGCTGCAGTTAGAGCCTCCCCCATGAGTTTGCACCTTAT TAAATCAGAAGGCGAGAACATGTAGCCTGTGATTTGCCTCTTCTGCATGACAGCCAGCAA ATGTCGGAAGCCCTGTGGTCTCTCAAGTTTCACGAAAAACTAAGTCAGTGCCCTCAGAGT GAGGAGCAGATATCCATTAGGAAGGGCACTTTTTATAGGTCTGTTTCTTGATACTGAGAA TGAAAGAAAAAGCCTTTCGTTTAAGGGCATCCTCTTCCCTCTTTGCAGCAGAGGCCAAAG TGTGTATGCATCGCCCACTGCTTGAAACCTGGGGGGGATTTTCCATCCAGAGATATCAGG TGTGTTTCCAAGGACAACTTTTGAATATATTAAAGCTTGAATACTCCTCCCAAGTCAGTG TTTGCTGAGGCCCTACTGTGCACAGAACACAATGCCACATCCTCTGGGAGAGATGCAAAG ATATTGTTTGCATATTTCTTTTTCCTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCG CCCGGCTGGAGTGCAGTGGTGTGATCTCAGCTCGCTCTAACCTCTGCCTCCAGGGTTCAA GCAATTCTTCTGCTGCAGCCTCCCGAGTAGCTGGGACTCCAGGTGTGCGCTACCACGCCC AGCTAATTTTCGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCATGATGGTCTCA ATCTCTTGACCTCATGATCCGCCTGCCCCGGCCTCTCAAAGTGCTGGGTTTGCAGGCATG AGCCACTGCACCCGGCCTTTTTTTGTTTTGTTTTGTTTTGTTTTGTTTTTTTGCACCAGA GTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAATCTCAGCTCACTGCAACCTCT GCCTCCTGGGTTCAAGCGATTCTCATGTCTCAGCCTCCGGAGTAGCTGGGATTACAGGCA CCTGCCACCATGCCCAGCTACTTTTTGTATTTTTAGTAGTGACAGGGTGTCACCATGTTG GCTAGGCTGGTCTTGAACTCCTCACTTCAGGTAATCTGCCTTCCCCGGCCTCACAAATTG CTGGGATTACAGGTGTGAGCCCCCGTGCCCAGCCTTGTTTATGTATTTCTTCTCTGCTGC CTTTTACCTTGTAGAACATAGCAAATGCTTTGAACACACCTTGACATCATTTGAATAAGG CCTGATATCGGAGACCCGGTGATAAAGACTTAGAATCATGCTGTCTCTTCTGCAAATAAT TCTGGTTATTAAAGAGAAATCAGAATGTGGGGAAGTATGTATTTTTTGCAAGCCTGTTCC CTTTTAATGTTTGAGATCAGGTATGTGAGTTAGGGTACACGATCATGTTTGTTACATATA AAGTGCCTTTGAATGGCAGATGCAACTTGAAACACAGTGACAATGAGGAGAAGATGCAGA GGACAGAGCAGACCCCCCACAAGATTGGTAGTAGAGTGCCCTGCGTCTGTTGAAATCATT TTTGTCAGTCCAGGCAATGCATTGATTCCGCTGGTTGGGTAGTTTCTAAAAGTCTCTTTA ACATTAAAAGAGTAAGAGAGACCAAGCGCGGTGGCTCATGCCTGTAATCCCAGCATTTTG GGAGGCCGAGGCGGGCAGATCACTTGAGGTCAGGAGTTCAAGACCAACCTGGCCAACATG GCAAAAACCTGTCTCTACTAAAAAATACAAAAAATTAGCCGGGCGTGGTGGTACACGCCT GTAGTCCCAGCTACTCGGAAGGCTGAGGCACGAGAATCACTTGAACCCAGGAGGCAGAGG TTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTGCCT CAAACAAACAAACAAAAAGAGACAGCCTGTGTATTAGTAAGATTTCTTTCAGTTCCAAGT GGCAAAACCCAGTTCATACTACTTTAAGCAAAAGTAAGAACTTACTGGCCAGTGTCTGGA GAGGCCAGGGTTAGTGCAGGCATGGCTGGATGCAGGCCCTCAAAGGGTGCTGTCAAGAAT CAGCCTCTCCCCACATCACTCAGCTCTGCTGTTCTTTGAGTTGGCTTCATTCTGTGGCTT GCTTTTTTTATATGATGGCCCATAGCGGCCTCTGGCTTCCATCCTACCACCTTAGGAACC TTATTGGAAAGTGTGTCTTCTTGCCAGTAGATCTAGCCAGAGCCTCAGGGCTGATTCTTG GTGGATTACCTCGGGTTGTTTGTCCACCCCTAGACTAGTCACGTGGCCATGGGTTGGGGT CTGGGGTTGGTGTCTGGGTACTTACTGACTGGGTCACATGCCCTTGCATGGAGCTCAGGG TGAGGTGGATCTAGCTCCACCACAAACCTCATGGTCCAAGAGGAAGGTTTGATTCCCCAG AGACAAATCTAATTTGCCGATACCAGCAATGGGGGGGATGAATGCTGGGCAGGCCGAAAC AGCAGATGGGAATCATGAGCAATACCCTTGCTGCTCTGGGTAGAAATCTTTTAGACCCAA GCAGATATCCAAGCTGCTCATTTGGCCCGATGAGAAGAGAAAAACAGAAAACAAAAGCTC TGAGTGGGTAGAGCGTGGGGGGAGCTTGAAGCTGTTATTAAAGGAAGGTATGATTAACTC CTAACTCACAGCCGCTTCAGCTCATCTCCATGGCTCAGCCACCAGGCCAGCCTTTGCTGT CACCTAACAGATAATTATTGTCTTTTCTACAATATGATTAAGTGGAAGGAGAATCAGAAC ACTGTAGAACTGGATCTGATATTTCTTGTTAGCATATATATATATATTTAATCTATGTGC TTGTCCTTGAAAACAGCACTTCCTGTACCCAGCAATCACAGAGCTGCTCTTGGAATTTAA CACCCTGGTGGTTCTCAAATGCCATCTGAAAAACATTATTAGTGTTACCCATCATGACCT CTGGGTAGTGGAAGGTGAATGGGAGAAATCTCTCCCCATTTGAAGAAATAGGGAACCAGT CTCACTTTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTTGCTCACTGCAACCACCACC TCCCGGGTTCAAGCGATCCTCCCACCTCAACCTCCCAGGTAGCTGGGTCTACAGGCGTGC GCCACCACACCCGGCTAATTTTTGTGTTTTTAGTACAGAAAGAGTTTCACCATGTTGACC AGGCTGGTCTCAAACTCCTAACCTCAAGTGATTGGCCCACCTGGGCCTCCCAAAGTGCTG GGATTACAGGTGTGAGCCACTGCAGCCCAGCCTACGAAGTTGTTTTTGCGGTTAAGCAGC AATTTGGAAACGAAGCATTTCTGAGGAGCTCAGTTTAAGAAACACTGTGATGTTGTGTTT TAAACCTATGAACTCCCCTCCGTAGCTCATCCCTCTACTTTTCCATCTAACCCCAGTACT GGCACCTTCTCTATGATTAGTAAATTTCTTCAGCTAGAAATGTTACAGTCTGTTTTTTAA CAATGAAGTCAGGACCCAGTGGATTATAGCATTGTTACACTTCATGCTCATGTTATATAA AATTGCATAAAATGTATTAAAATTTATGTCTGCTCTTATCTCTGCCTTGCAAAGAATGAA TTTGTATAGCTTTTAACTAAGCATGTAACGGGGGCAGCACCACATCTGGAATTCAAGCTG ACTTTCTCACGTACCGTAATCTTTGTGCTTGGTCTAATAAGTACAACCCCATGTGTGTTT ATCATTTTTTTATTGTATGCACAATCTTGAGAGTACATTCCTTTTTAGTTCTGTATTGAT TTGTTCTCTTGGTCGTCTGTTCAGAAATACATTCAATACCTTTGGGGAAGGGCAAAGATG ATTTCTGCAAATGTTGCCCTTTTTTATTAAAAATAGCTTCTGTGGTCTTTCTTATAAAAG CAATACATGTTTATTGAAAAAGAAATCAGGCTGGGCGTGGTGGCTCACACCTGTAATCCC AGCACTTTGGTAGGCCGAGGCAGGCAGATCATCTGAGGTCAGGAGTTGGAGACCAGCCCG GCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAAGTGTCGTGACA CATGCCTGTAATCCCTGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGAGAG GTGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCACCCTGGGCAACAGAGCGAG ACTCTGTCTCAAAACAAAACAAAAAACAGATAAGGAAAAAAAAAATAGGCCGGGCGCTGT GGCTCACACCTGTAATCCCAGCACTTTGAGAGGCCAGGGTGGGCAGATCATGAGGTCAGA AGATCAAGACCATCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAATC AGCCAGGCCTGGTGACACATGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAGAA TCCCTTGAACCAGGGAGTCGGTGGTTGCAGTCAGCTGAAATCGCACCCACCGCACTCCAG CCTGGCAACAGAGCGAGACTCCATCTCAAAATAATAATAATAATAATAATAATAATAATT TTCTGGACTTTTTCTGTGTCTATAAACATAGGTATATATATTTTTTAATTTCCAAAAATA AAATCATACTATAGTCATTATTTGCAACCAGTTTTTCCATTTGTCTGGCTGCAGGTGGGA ATGGAAGTGGCCCCACATCTCAAAGAAACCCTAAATAAGAACTTTTTTGACTTCCTCCTT ACGTTCAAACAGGTAAGAGAACACTATCAGAATAGCTCATCGATATAACAGTTCTATGAT AGCAAATTCACAAAACCCAGTTGGTTTTCCAAGTGGAGAATGCCTTAAAGCTCTTTAAAT GTGCAAGCCCTGGAAAATTACACTAGCTTCTGTTGTAGACAATTAAAATGTGTTGATTGT ACTGAATAAGCGGAGAAAGTTAATATGCATGTGTTAACAGGAAACGTCTCCAGTCGATCA GCCTTGCTTCTGAGCATCTGCTGGCTCCATTTTTATCAGGTTCCTGCTTTCCACAGCGCT CATTCCCAAAACAGCTCGGCTTGGTGACATGAGAAACTTTCTGTGTTTTTTTTTGGTTTA AAAAAAAAAAACAACCGAGAAACCAGGCTATTTCTCTCAGGGCTGTCCACATGCTTACAA GTATGCACAGTCTGTGAGTTGTGTATGTTTTGTTTGTTGTTTGGTTTTTCCCCTCCTTTT CTAAGTGTTTGTTTGGCCTCCTGTAGATTCATGGGGATACGGTCCAGAACCAGCTGGTGG TCCAAGGAGTGGAGCTCCCATCTTACCTCCCCTTGTACCCGCCTGCCATGGACTGGATCT TCCAGTGCATCTCCTACCATGCCCCCGAGGTAACTGCCAGGTGGCTTCAGTGTGACGCTC ACCTCCTGTATGGTGACAGCCCCTGCCCACTGTGCCCTTTAACGTTAATGGGACCCTTTC ATAACAGCTATAGCAATGTTAGTGCTAGCCAGCCTTTATAGAGGGCTTGCCATGGTGGCT GGCTCTGTGCTGAGTGCTTTTCTGAGATAGTCTCATTTTGACAGCTGTGGAAGGGGAATG TGGTAGCTCCAGAGGCCATGTACCTAAGTGAGGCCACACAGCTAGAAAGCAGTTTGGTGG CTGGGTGTGCTCATATCTGTAATCCCAGCACTTTGCAAGGCCAAGGTGGGAGGATCACTT GATTTTAGGAGTTTGAGACGAGCTTTGGCAACATAGCAAAACTCCATCTCTACAAAAAAA TAGAAAAAATTAGCCAGACACGGTGATATATGCCTATAGTCCCAGCTACTCAGGAGGCTG AGGTGGGAGGACCACTTGAGCCCCAGAGTTCAAGGCTACAATGAGCTGTGACTGTACTAC TGCACTCCAGCCTGAGTGACAGAGCAAGACACTGTCTCATTAAAAAAGAAACAAAAAGGA AGATGGTTGGTGACTTGATACAAACCCATAGAATTGGGCTCCAGGGCCAACAAGCCTTAT TGCGTCTTCACTTAACCTTCATGTACCCCTTTTGTGTTTATAATAATCCAATAAAGTCTG TAGAGCAGGTATTTTATGGAAGGAAAACAAAACTCAGATGCTTAATTTCTTTTATAATTT TATTTTTCTTTTCTTTTTTCTTTTTTGCCAGTTGAAGTATTGTCAGGAATTGAAGTGACA TCAGAATCATAGCAGACACATATTTTCTTTCTTTTCCAAGACTGAGAAGCAGTTTTAGTA GAACACCAATTCAAACTGTCATGAAGACTGTGATAGGCCGGGCACGGTGGCTCATGCCTG TAATCCCAGCACTTTGGGAGGCTGACGTGGGTAGTTCACTTCAGGCCAGCAGTTCAAGAC CAGCCTGGCTAACATGGATATATAGGTGTATATCACCATGCCTGGCTAATTTTTTGTATT TTTTTGTAGAGATGGAGTTTCACTATGTTGCCCAGGCCTGTCTTTTGTAAAGACCCTGTC TCTACAAAAAATACAAAAATTAACTGTGCGTGGTGGTTTGTGCCTGTAGTCCCAGCTACT CAGGAGGCTGAGGCAGAGAATCGCTTGAACCTGGGAGGCAGAGGTCGCAGTGAGCCGAGA TTGCACCACTGTACTCCAGCCTGGGCAACAGAGCCAGACTGTCTCAAAAAAAAAAAAAAA AAAAAAAAGACTGTGATAGATGAAGCTTTCCTTGTCTTTATTTGATCATTGAAAAGTAAA GAGAGACTACAAAACAAGGACATATAGAGCAAAGCAAAGTTGAAAGACATCTGCCTTTTC CTAGATCTTGCCAACACATGTTGAAAGCTGTACAGAAAAGAAAAAAAAAGGACATGACTT TAACCGAGCAATCCCACTTTTACGAATTTATCCTGTAAGTTAGACGAGTGCATAAACATT ATAAACACACACAGAGATGCACACACGGTTTGTTCACGGTAGTGCAAAATTGGAGGCAAG CATCAGAGAGGACTGGTTATGGTATGTGCATTCAGTGGGGTGTTAATGGGGCCATTTAAA ATGATGGAGACTCCCGATGATCTGTACATACTGACGTAAGGGTATTCATGGTATATGGCT AAGTGCAAAAAGAAAGTTACACACATTGCTGTGTGTGCTGTAAGTGGCAGTGTGGCCTAG TGTTCAGGTGTGGGCTCTGGAGTCGGGGTGCCTGGGTCTGCATCTCAGCTCCGTTAACAG CTGTTGTGATAGAGTAGGGAGCAGGTAACTTGTTCCTAACCACTCTGAGTCTTCTCTCTT TATCTGTAAAATGGGAGCAATATTAATGATTCCTATTTTCTAGTCCGTTGCAAGAATCAA AGAAGTCACTGTATCTACGGTGCTTAGTGTAGCGCCCCACATCTTAGTACTCGCAGACAT GATTTTTATATCTGTGCGAGAGAGTTGGGAAGGAGAAATGACAGAACATCACTGGAGTGT GAGATTTGGGGCCAGCGTAACTTATTTTTCTTTGCCTATCTGTTTTTTTTTTTTTTTCTT TCTTCCTTTGAGACAGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCACTGGTGCAATCTC GGCTCGCTACAACCTCCACCTCCCAGGTTCAAGCGATTCTCATGCCTCAACCTCATGAGT AGCTGGGACTACAGGCATGCATCACCACACTCAGATAATTTTTGTATTTTTAGTAGAGAT GCAGTTTCACCTTGTTGATCTCGTGCTGATCTCTAACTCCTGGCCTCAAGTGATCCTCCC GCCTCGGCTTCCCAGAGTGCTGGGATCACAGACAAGAGCCACCGTGCCCAGCCGCCCATC TCTGTTTTCTAACTTTTCAACAAGTATGCACTGCTTACCTTTTTACTTTTTGAGATTCTA AATTATGAGGAGAAAAACTGGGACATCTTGTACTTCAGGTGAATAGTCTTACCATTAAGT AAATTGATTTTAAATCAAGCCAGTATAAAGGAAAGATTGTTTGAAGTTTTGCTGCTGGTT CTCTATGGTCCTCAGCATAGTTTCAGCAACCACATGCTGTCCTCCGCTTCTGGGAAGGGT ACCATGAACTCGACTGTTTTCTTGGTATTCCACTGAACGACGGAAACATACAAGCAGGAT TGACGTGGTGAAATGAGAACGCTTTTTTTTTCTTATTTTAGCGAAAGGCAAAATCAGATT AAAAACAAAATGTCACAAGGCAGTCTTCTTTTTATTTTAAGCCCCAGTCATCTCAAAGGA TGGCAGAAGCTGGGAATAAGCTCTAGGAAATCATTATTGCACTAGAATAAGTGATTAAAA AATTAGGTCAGCTGAATAATAATAAACTCTGATTCTTGGGCACACTTAAAGGACATGCAG TGTCTTGTTAAAAAAAATAGTCATTTTCAAACTGCAGAAGAATTGATGTCGGTATGGAAG GTGGTGTTAAAGGTGCATGTGACAATTTGGTGCCTAAAAGCTCTTTGATAATGGCCGCTA TGAGTCACCTGCAGAGTAGAACTGTGTGTATCCATTAGAGGCCAAGACTTCAAAATAGGG GATGGTAAAGTTCGGCTGCAGCAATTGGTAATATACAGGGCAGGCAAGTGAGAGAGGGAA AGGAGAAATACCTTTAGTTGTGAATATCTCATCTACAGAATTTCAAATCGAAATTGAAAT CCAAGGTAAAAAATCAAGGCATGTCTTAGTCCGTTCGGGCTGCCATAATAAAGCGCCATA GAATGTTTAAAATAGAAATGCAGCCTTGGCCTGACTTCTTTTCTCTCCTCCTGTACTTTT GAAGTGGGTAAATAATTATAAATAACCTAATCTGGAGATCACCTTAAAAAATCCAACAGT TAAATATGGTTGTGGTTCTCCAACTCCATATATATTGGTAAAATGGTCATTGAATTAGAC ACAAAGACATGCTCTTTTTCCCCCAAAAAGTATGCATGTAAAACTTGGTGAAATTGTCTA GTTAGTTGTGTTATACTAGTGTCAGTTTCCTAGCTTTAATAATGCATTATAGTTATGTAA ATGGGAGAAGCTGGGTGGTGGGTACCCAGGACTTCTCTCTACTGTTTTTTTCAATTACTG ACGAGTCTATAATTAATTCAGAATGAAAAGTCTTTTAAAAATCCTTCAATTGGGATGAAT ACTCCATTCTCCATGATGTGATTATTATGTATTGCATGCCTATACCAAAACATCTCATGT ACCCCATAAATATATACACTTACTATGTACCCTCAAAAAATAAAAATTAGGCCAGGCGTG GTGGCACATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCTCTTGAGGT CAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAATACAAA AATTAGCCGAGTGTGGTGGCATGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGG GGGATTACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACACCAGTGCACTC CAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAAAGAATAAATTAAAAAAAATAAATA ATTAAAAATTAAACAGAAAACAAAAACAGACATCTGTCAGTTAGGGGCAGTTTGAAAAAT GCTGTTATATCCATGGCATGGATTAAATAGCCATGGATTAAAAGAGTGAGGTAGATTTGT GTAATAACATGGAGAAGAGAGGGCCATCTAGATTCTCCATTAAAAAAGGCCATATTTAAA TATCTCCAACCCAGTATTTATAAGAGTATCCCATTGTGTAAAAACAAAACTAGGCTTCTG TAATAATATATATCCATAAAGCACAGGCAGAATTCTAGATAAGAACATCAAAGTCCTAGA CAAACACCAAAGTGTTGACAGTGGTGATTTCTAGGACATGGAAGTTGGGAGGGGGGGACA TTCGCATCTTTCTTGATGCATGTCGATGTTGTTGGGACTTTTGTCTATAAAGCATTTCTT ATTTTTACAATTTTTAGAAAAACAAATGTTACATAAATAAGTGGCATGTAGGGCCAACAG CAACAATAACAAAAGCCTAAAAAACAAACCAGCACACCAAGCAAATGCCTGCCTTGTGAA TCTTCTGAATCTTCAAGTTCTGCTGTGTGTGAAAATGAAAGAAATATGCTGAGCTGCTTT TTCAGTGGTTGATCCCAGCCAAAGGGCTTGTTTCAATCTCTGTCTGCTTTGAGCTGTTGT TCATCGTGTTCTTGCCAAAGATAATCAATTCTGTCACTTCTTAGAGGGGAAAAAATCAGT AACCTCCAGCAGACCTGCCCGAGGATCTATAACATTTGGCTCTCCGAACACTTACATGTA TTCCCAAGTTCCTTTATGACAACAGAGCCTTTGGTTTTTTAAAGTTATATTCTTGGATGC ATTTTTAGTGCATTCATCTTTTGTGAGAGAGGGAACTTTTTAAGCATTTAACTTGTCTTA GTGGTAAGAATCTTTTGTCCATATGTTGGGATTTGCCCTAGTTAATCTTTCCAGAATTGG TGGGCCAGGAGGTCTCATTTATGTGTGTGTGTATGTGTGCATGTGTGTGTGCACGTGCAT GCATATGAGATACAGTAAACCTCACGAAGGCATGGGTTTCTGTGTTTTCCTCCCATCTTA CCCTCAGTGTCTGGAACAGTGGCTGGTATAGTCATCCCTTGGTATACTTAGGGGATTGAT TCCAGGATCTCCATGTATATCTTTTTTTTTTTTTTTTTTTTTTAAGACGGAGTCCTGCTC TGTCACCCAGGCTGGAGTGCAATGGCCCGATCTCCACTCATGGCAACTTCTGCCTCCCGG GTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAGTAACTGGGACTACAGCCACGCCACCAC GCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTCTCATCATCTTGGCCAGGCTGGT CTCGAAATCCTTACCTCAGGTGATCCACCCACCTGAGCCTCCAAAGTGCTGGGATTACAG GCGTGAGCCACTGTGCCCGGCCCCCACGTATATCAAAATCCATGCTGTGAGACTCAAGTC TCACAGTCTCACAGTTGGCCCTGTGGAACCCGTGTATACTTGAGTTTGGTGTCTCACAAA TACTGTATTTTCGTTCAGCATATGGTTGAAAAAAATCCGTGTCTAAGTGGATCCACGCAG CTCAAAACCATGTTGTTATTCAAGGGTCAACTGTATACTAAAGTTGCTCGTTAGGTAGGC GTTGAATGATTATTTCTGTGTGTCAGGGAGTGTCAGTGTGATGATTACACAGAATCTCTT TTCCTCTCTTAGCCTTTTCCAAAGGCCACTTTGCTATTGGTCTTTAAGAATGACTTTTCA AATGTAAATACCCAAGAGTGGGTTAGGGAAGCCATTTATGATGTGGTCAATTTTGTCACC AGCTAGGGTGCTTTTGGCTGCAAGGAACAAACATCTAACTAGTCTGGCCTCCACATATAA TTCCATGTGTCCTCCTCCACAACAAGTGGAGGCTCTCGGGTGATCAGCTTCAGTGCATCT TTTTGCTCTGCTGTCCCTGATTAGTAGCAAGGTGGGGGCAACCATTCCAGGCATCACGTC CAGAGCCGACAGCATCCAGGGAATCTTTGATTCTTGGGTCCTTGTTTAAGAACAGGAAAC CTTTCTCCAAATCCCCCCGAAGACTTCCCATCCTGTCTCAGCAGCTAGAAATGGATCATG GGCAAGGGGAACGAGAGCCACTGTGATTGGTTTGGGTCTGTATTAATCTGCTTGGGCTCC CTTAACAAAATACCCAGACTAGGAGCTTAAACAACAGACTTTATTTTCTCATAGTTCTGA AGGCTAGGAGACCAAGATCAAGGGGCCAGCAAGGTTGGTTTCTGGTGAGGCCTCTCTCCT TGGCTTGGAAACTGCCACCTTCTTGCCGTGTTCTCACATGGCTTTTCCTCTGTGTACACG CATCCTTGCTGTCTCTTCCTATAAGGAGGTTAGTCCTGTGGGATTCGGATCCCACCCTTA TGACTCCATTTAACCTAGAATAGTGATATTAGGGGTTAGGGCTCCAACATAGCAATTTAG GGGAGATATAATTCAGTCCGTGACAGAAGCCAACCTAGTTTATGTGAGGCATAGATGGAA ATCTGAATAAAATCAGGGTTTTGGGGTAGGGATTCCAACAGTATCTCCAACGTCAGCTCT CACTTATTCAGGCAACATGACAGAGAGGGGTGCCACCAGAAAGGGTGGAATTGCACTTAA GAACCCTCCTTTTATTTTTTTACTTTGGGTCCAGACGTAGATATAGATCCCTTTTTTTTC TTTATTTTTTACTTTTTACTTATTTATTTATTATTATTATTATTATTATTATTATTATTA TTATTATTATTATTATTGTTTTAAGACAGGGTCTTGCTCTGTTGCCCAGGCTGAAGTGCT GTGGTGCAGTCTTGGCTTACTGCAGTCTCGACCTCCCAGGCTCAAGTGATGCCCCCACCT TAGCCTTCTGACTAGCTGGGACTATAAGCACACACCACCATGCTTGGCTAATTTTTAAAT TTCTTTTAGAGATGAGGTTTCGCCATGTTGCCCAGACTGGTCTTGAACTCCTAAGGTCAA GCCATCTGTCCCCATCAGCCTCTCAAAGTGCTGGGATTACAGGCATGAGCCATCGTGCCT ACCAGGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATAGGTCTCACTCTGGTGCCCA GGCTGGAGTTCAGTGGCACAATCACAGCTCACTGCAGCCTCCACCTCCTGGGCTCAAGTG ATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACCACAGGCACGTACCACCACACCCAGC TAATTTTTTAAAAAATTTTATGACTGGGCGCGGTGGCTCACTCCTGTAATCCCAGCACTT TGCAGGGCTGAGGCGGGCAGATTGCCTGAGGTCAGGAGTTCAAGGCCAGCCTGGCTAACA GGGTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCCAGGCATGATGGCACACAC CTATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCAAGAGGCGGA GGTTCTGGTGAGCCGAGATCGCGTCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCG TCTCTCTGTCTCAAAAAACAAACAAACAAACAAACAAAAATACTTATGTAGAGATGGGAT CTCACTATATTGCCCAGACTGGTCTTGAATTCCTGGGCTCAAGCGAGCTTCCCACCTCAG CCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACCCCTGGCCTGCACAAATCCCAT TTTTGCCACTTATTAGGAAGTGTCTTAACCCTGTCTGAGCTTTGGCTTTTGCATCTGTAA AATGGGGATAATGTTCCATGGACCTCACAAGGACATGGTGAAGAGTAAGAGAGTAAAGGG AAGTCAAGGACTTAGCCCGAAACCTGGGCAGTGCTCAGTGTCCTGTAATTACCTCTGGTC TTGGGCTTGACCTTCCCCAAACCACTGCCCTAAATGATCCTTCTTCCATTGATTTTCTTA AAAACAGGAGCTCTTTTAAAGATATGTAATTGTCTTAAGATAGCTCCAAAGCCATTAACA GTATTCCAATGAGTTAAAAAAAAAAAATCTGCTTCCTTTGGCGGAGGCGGGGAAAATAGA CTTCAAACTGTGTTGGAGAAGAAATGTATTGAAGAACGTGGCCTTTGATCCCAGTCTGCC CAGGTTCATGTCTGCCTGCCATCACTAACTGTGCGACCTTGGGTGAAAAACACTGCTATT CGTGGCTTTGTTTTTCATCTGTGAAATGGGAGAATAGAGCCCCTGCTTCAAGGGTGGTTG GGAGAGGTAAGATCGTGAGTGCAAAGTGCTTCTCACCATGGCTGGTGGGCACTAAGCTCT AGCCCAGTGTTTGTTGCTGATATTACTAAGTGCACCTTGGGCACCTCTTAAAATGGGGAA GAATGTGGGGTTACAGAAGAGGTGGGGAGCAGAGTAATTATCGTTCTCATTCATGCCCTG GAGTGCAGGAGTTATCTCCCATCATCCTGTAGTGACCCCACAGATGAGATGATACCACTT GTAGCCTTTCAATAAGGACAAGGAGACCCAGGTTCGACAGAGTTGGCAACTCTTCCGAAG TCTCATCATTGGTAGTTGGTGAGGTTGGATTTGAATCCAAGTGTGCCTGATGCCAGGACC CTAGCTTCTGTTGATTGATCAGTTGATTGATTGAGACAGGGTCTCCCTCTGTCTCCCAGG CTGGAGTGCAGTGGCATGATCTCAGCTCATAGCAGCCTCCACCTCCTGGGTTCAAGCGAT TCTCCTTCCTTAGCCCTCTGAGTAGCTGGGATTACAGGCACCCGCTATCACACCTGGCTA ATTTTTGTATTTTTAGTGGAGACGGGGTTTTACCATGTTGGCCAGACTAGTCTCGAGCTC TTGACCTCAAGTGATCCACCTGCCTCGGTCTACCAAAATGCTAGAATTATAGGTGCGAGC CACTGTACCCGGCCCCCTCCTTCTATTTATTACACTAAATGCCATGAAAGTGAATTTTTT TCTCCCCAAGCCTCCCCATCCCTACCAGACACTGAGAATTATCTTAATGGACATGTGGCT ACATTCATTTTAGAGTTCGACTTTGGAAATCTCTTAGAAATGTTACTTTAGCTCCTCCAA CCTGATTTTTTAATTATTATTATTTTTAACATAATAGGCTCTGCTGACCGAGATGATGGA AAGGTGTAAGAAACTAGGAAACAAGTAAGTATTTTAAGATTCATAAAGCATGAGTTTGAA AATGGCGTTGGCTGCTATTTTTGAGCTTGGCCTGCTTACCTGGGTATGAGCTGAAGAGAG AGAGGCAGGACTGCATGGAGGTTTAGAATGCTGGAGTCCGGTTGCCTGGCCTCAGACCTT GGCTCTGTTCTGTCTTAGCCCTGTGACCTTGGGCCGCTTGCTTGACCTCTCTGTGCCTCT GTCTCTTCATCTGTAAAACGGGAGTAATAATAGTTCTTTCAACTGGGCGTGGTGGCTGAT GCCTGTAATCCCAGCATTTTGGGAGGCTGAGGCGTGTGGATCACCTGAGGTCAGGAGTTC GAGACCAGCCTGGCCAACGTGGCAAAACCCCATCTCTACTAAAAATACAATAACTAGCCG GGCTTGGTGGTGTATGCCTGTAGTCGCAGCTACTCAGGAGACTGGGGCAGGAGAATTGCT TGAACCCGGGAGGCAGAGGTTTCAGTGAGCCGAGATCATGACACTGTACTCTAGCTTGGC GACAGAGTGAGACGCTGTCTCAAAAAACAAAAGAAAAAAAGTAATAATAATAGTTATTTC CCCATGGGGCTGTGGTAGGTGGTTGGGCTAGGATGAAATTGATCTCCCTGACTCTCACGA ATATGAGGTTGTCTCTCTGCTTTCCTTTTAGTGGTAGATACATGGAAACAGCCTTGCATG GGCTTTGTTTACCACTGTGTCCCCTGTGCCTGGTGCCTATAACATAAGATCTCTTTACTA AGAAATCTCTTGCATAAACTGGCCAGACACAGTGGTGCATGCCTATAATCCCAGCACTTT GGGAGGCTGAGACGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACAT GGTGAAACCCTGTCTCTACTAAAAATACATAAAATTAGCCGAGCATGGTGGCGCATGCCT GTAATCTCAGTTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGG TTGCAGTGAGCCAAGATCGTGACACTACTCCAGCCTGGGCAACAAAGTGAGACTCCATCT CAAAAAAAAAAAAACAAAAAAACCAAAACTCTTGCATAAACGATGTGGATATATATTTAC AACATGGATCAATATCGTTACTTAATGTTCTGTCTCATTAGTGCACCAGCTTATTGAATG CTCGCTCTTCTTCTCCTTAAATGAACTGGATCACTTGCTGATCTGTCTATCCACCCTGCC ATCTAGCCATCCATCCATCTAAACATCCAGTTAATTCAACATTTATTGAGTTGCAGATAT GTACAGGACACTGTGTTAGTCTCTCCAGTTTACCTTTTTACTCTGATTTTTTGTTTTTCC CCAACCCTACCGCTAAAGAGCTGTTAGTCTTCCTTCCTGGCAATATATATTCAAAAATTA AAGCAACTTTGATTGAGGAGAAGCCAGGCTGACTTGGGGATCTGTGTCTTGCAGTGCCTT GCTGTTGAATTCTGTGATGTCTGCCTTCCGGGCTGAGTTCATCGCCACAAGGTCTATGGA TTTCATTGGCATGATTAAAGAGTGTGATGAATCTGGTTTCCCCAAGGTAGGCTCTTGACT TCATGCTCAGTAGGACACAAATAAGCGGTGTGTATCTGATAGCTCTTGAGAGACAGTCCG GTTTTGGGAACAGCATGGGCCAGCAGGAACACAGGCGAAGGCTCTGTTTCTGAGGAACGC AATGGAAGATGAGTTAGAGGTTGGGATTGTCAGACACTGTGTGATTGCTATGCTTCAGGC CCCCATGAGCCCTAAATCTATCAGATTGGCTCACTATGAAGGATTTAAGAAAGACTTTGG TCTAACATATTTAAGAATATATCAGGCTGGGCACGGTGGCTCATGTTTATAATCCTATCA CTTGGGAGGCCAGGGCAGGAGGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGGCAA CACAGCAAGACCCCATCTCTACAAAAAATCAAAACTTAGCTGGGTGTGGTGGTGCATTCC TGTAGTCCCAGCTACTTGGGAGGCTAAGGTGGGAGAATTGCTTGGAGCCCAGGAGGTCAA GGCTGCAGTGAGCCATGATTATGTCATGAAGCCTGGTGACAGAGTGAGACCCTGTCTCAA AACAAACAAAAGGATATATCTTCATTCATTATTTATGAAAAACTTTGTCCAGTAGAATAT TATGGCCCCACATTAGACCAACAGATGGAGCTAACTCTGTGTGAGCCTCTCAGTGTAGCT GGGGCAGATATGTGTGATAGAACTTTAGAAGGAGGTTGTTGGAAGATTAGCCCCAAGAAG GATTAAACATTACAACCTTTTCTCTTTTCTTTTCTTTGAGCTTCAAGTTAATTTGATTTA AAATTTCCATAACATGATGGTTTGACATGTTTCTTAGCATCTTCTTTTTCGATCACTGGG ATTAAACTTGGCCTTGGCTGATCCTCCTGAGAGTGACCGACTTCAGATTCTCAACGAAGC TTGGAAAGTCATCACTAAGCTGAAGAACCCACAGGTGAGTGGCCATTTTATTTTTATTTT TATTTATTTATTTATTTATTTATTTATTTTGAGATGAAGTCTTGCTCTGTCGCCCAGGCT AGAGTGCAATGGCGCCATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTC TTCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGTGCCACCACACCCAGCTAAT TTTTGTATTTTTAGTAGAGACAGGTTTTCACCATGTTGGTCAGGCTGTCTCAAATATCTA CCCATCTTGGCCTCTCAAAATGCTGGGATTACAGGCGTGAGCCACTTTGCCCGGCCTGCC ATTTAAACTTTAAATCAACCACTTTTTGTCCAAGTTTTGGCATCTGCTCTTTTAAAAAAT TACCCTTCCAAGCTGAACATGGTAGCTCACACCTATAATCTCAGCACTTTGGGAGGCTGA GGCAGGAGGATCACTTGAGGCTGGGAGTTTCAGACCAGCCTGGACAACATAGCAAGACCC CTGTCTCTATTTGAACTAAAAAATAAAAATTATCTTTTCATTAGTTATACATTTTTCCCT AAAGAAATCTATTTATTATAATTGTATTATTTGTTTACCTGTAATGGAGAATGGATAGCT TTAAAGATGTAATTTCTTTGATTTTTTAAAAATTCAATTCTCACAGCCTTAAGATGTGCT AAAAGTATAAAATTACATGATCATGCGTTCAGAACTGCCATAAAAAATACAACTTAAAAA AAATGCATAACATTACAGATATTTGAAACTTTATGAAAAATCAGTTAACTTTATAGTGGG CATCCAAAATATAACAGTTCGTAAGATTTAGGCTTGAAAATATCGTTAGTAGGATATTCC TAAATAAAAGATCAGCCTTTAAGCCAGTAATTAGCAAAAGGAAATTCCCGTTTCCAACCA TTGAACAGAGCCAGCTGAAGCCTCCTGTTTGCTGTAATGCATACTATGTTGTACTTAATG TTAAGATGTTTTCCTTTCTCTTTGTAGGACTACATTAATTGTGCCGAAGTGTGGGTGGAA TACACCTGCAAGCATTTCACGGTATGTGTGACTGTGGTATTGTTTTTGAAAGAATTAGAT TTTTTCATGTTTATAATAGTGAATTAGCCTAGTTTAGGTATTGAGGCATTTGACAACGGT ACTTGCTCTTGTAATTTATAAAAATTGCATTCTTCATAATAAAGCGTGATGGAGCATTAA TATGTGTACTATAACAAAAAATAACTGTTCCATGTTTACATTTAAGTTTGGAAAATGCAG CATTACACAAAGTTAAACCATTTTTTTTTTACCATAGGATACCTTAGATGCTTACATGCT AAAGTGCATTGCGACTGTACATCAGAGTCTAGTAAGCAGCATTTCCCAAACAATTTGACT GGCATGTAATTTTTTTCCTAAGCAAATATTTCTTTCCCTAGGCACAGACTAGAACCACAG TTAGGGGAATACTGGGCTTCTCAAAGAGCAGAGACTTTAGAAGAAGATAGAAGTGGGTTC AAAACCCTTGCCAGAGTAATTTGTTTATTTTAATCAAGTCCTAAAAGTTTTTTTTTTTTT TTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGTGGTGGCGTGGT CTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCATCCTCCCG AGTAGCTGGGACTACAGGCGCCTGCCACCACGCCTGGCTAATTTTTTTGTGTTTTTAGTA GAGACAGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGAGCTCGCAATCAGCC CGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCTGGCCAAGCCC TAAAAATTTAAGTGTGGCATTGCTATGGTCTGAATGTCTGTGCCCTCCCAAAATTCATAT GTTGAAATCCTAGCCCCCAGGATGATGGTATTAGGAGGTGGAGCCTAGGTCATGGCAGGC AGAGTCCTTATGAAGGAGATTAATGCCCTTATAATAAAAGAAGCCCACCAGCCTGGCCAA CGTGGTAAAACCCCGTCTCTACTAAAAATAAAAAAAAAAATTAGGTGGGTATGGTGACAC CTGCCTGTAGTCCTAGCTACCCAGGAGGTTGAGGGAGGAGAATCGCTTCAATGTGGGAGG CAGAAGCTGCAGTGAGCCAAGATTGCACTCCTACACTCCAGCCAGAGCGACAGAGTGAGA CTCTGTCTCAAAACAAAAATAATAATAAAATAAGTCCTGAGTTGCTCACTGTCCCCTTCC ATCCCATGAGGACTTGGGGAGAAGATGCCGTTTGTGAGGAATGGGTCCTCACCAGACACC AAATCTGCCTTGATCTTGGACTTCCCAGCCTCCAGAACTGTGAGAATTACATTTTTGTTG TTTACAAGCTTCCTGGTTTATGGTATTTTGGTAGAGAAGCCCAAACAGACTAAGCCAAGC ACACATGCAAAAAAGTGCACGTATCATAAGTTTGCTGCTCAATGAATTTTCACAAGGTAT GACCATATAATCACCATCCAGAGTAAGAAATAGGAAATAAGTGACCCCGCAGAACCCCCA GAACTGCCTCTCCCTGTCACAACAGCCTTTGAGGAGGTGAAGGTAGACACCATCCTGGCC TCTAACACCAAAATTGATGTTGCCTCGTTTTGAGCATTAGGTAAATGTTGGTCCATTGAT TTTTGTGGTTTTTTTTGGTCCTATTTTTATTTTACATTTTATTATGGAAATGTAAAACAT ATGCACTCCCTTGTACCCATCAATCAGGAATTATCAATTTATGACAGATCTTGTTTGATT TATATCATTACCATGTCCCCTGACCCCTGGAATATTTTGAAGCATATCTCAGACATTGTA TCGTTTCATCTGTCAGTATTTCAGCACACCTGTAAAAATATAAAGATTCCATTGATTGAT TGATTGACAGACAGGATCTCACTCTGTTGCCCAGACTGGAGTCCAGTGGTGCAATCGTCA CTCACTCCAGCCATGACCTCCTGAGCTCAGGCAATGCTCCTGCCTCAGCCTCCCGAGTGG CTGGGACCACAGGCACATGTGGAGATGTAGAGATGGGGTCTTGCCATGTTGCCCAGGTTG CAGGGTTCACTTCCTTAAACCAAATCTAAATACATTATTCTAAGGAAAAAAGTTACTAAT TTTTTTTTTCTTCTGTTTTTGAGATGGAGTCTCACTCCGTCACCCAGGCTGGAGTGCAGT GGCATGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCA GCCTCCTAAGTAACTAGGACTACAGGTGTGTGTGACCACACCCCGCTAATTTTATGTATT TTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAG CAATCCACCTGCCTCAGCCTCCCGAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCA GCCGAGTTACTAATTATTTAATATCATCAGTACCAGTCAATATTCTGATTTCCCCAATTG TCTCATTTTTTTTAAGTTTATTTGTTGAAATCTGGTTGAAAATAAGGCTTCTCCATTGCA ATAGACATTTTAGGATACTTTTGATGTATAAGTTCTCTCTCAAACTGTCTCCTTCTCTCC TTCCCCTTTCTTTCCCTGTAATTTATTTGTTGAAGAAATTGGGTCTTTTGCTCTATAGAG TTGCAAAGACTGGATTTTTCCCATTGCATCCTTGTGATGGTGTCTGGCGTGCTCTTCTGC CTTTTGTATTTTCTATAAATCAGCAGTTAATTATAGAGACTTAAAAGCCATTCTTAGCTT GTGGGCCTTATAAAAACAGGCCCTGGGCTGGATTGGGCTGCAGTTGGCTGACTCCTGCTA TAGGTGACAAAAGTGAACAGTGAGCAGTTAGGTCAGACAGCTTGTAAGGGTGAGCCTGCA GTCTTCCGCAGTGCTTCACTGTTCTCTCTGCAGGCACCTGAGGGAGGGCCTGGGACAGGC AGGTGGAGAGAGGCACGGCCGATTCAACCATCACTCTGGGAAAGCAGAGACAATGTAAAG CCCCAGAACTTTTGAGAAGAGCGTTTAGTCCTGACTAGGTGTGGGGCTGTGGTACTAGAC CGGGTGATATGAGTGAGATTTCCTCCCTTCCGTTATTTTCAGCAGAATACTGAAATTGAT TTCCTGGAAGGTGTGTGATATATTCTGAATACGTTAGTCCTTTCCCCCAGGAACATGGTC AGCAGTTGCCATACAGTGTCTAATTCAGGTTTGGTTCCTTTTTCCTGCTTAGAAACGAGA GGTGAATACCGTTTTGGCAGATGTCATCAAGCACATGACTCCAGATCGTGCATTTGAAGA TTCCTACCCCCAGGTAACAGATTTGCATTTCTCATTTCAACATTGTTAGGAATTTTGTTC TGTTGAATTAAATAGGCGTGTTGTATGGGTCAGGCTATAAAGGCACATAATCCTGTGTTT GAATCATAGCTCTGCCATATCCTAGCCATGTGCCCTTTGATCAGTTACTTAACCTTGTTG TGCCCCAGTTTTCTCACCTGTGAAATGGAGATAGTAATAGTGCTACCTGAGAGTTACTGT GAGGATGAAGTGAAGCCCTCACACAGTGGCCTGGCACGTGGTAAATGCTCAATAAGCGTT GTCTTCATTGTTGTCACCAGTAAGTAAACTGCGAGTATTTTTAGTTAAATCAACTTTGTT TTTTCCTTTTTTTTTGAAACAGGGTCTCGCTCAGTCACGGAGGCTGGAGTGCAGTGGTGC GATCACCGCTTGGCACAGCCTCGACTTCCTGGGCTTAAGCATAATTTTTTTATGTGGAAA TAAATTTAAGCTTATTGGAAAGTTAAAAGAAAGCTCAAAGAATTCCTATTATTCTTTAAC CAGATTTACTAGCTGTTAACATTTGTTTTTTTTTGTTTTTGTTTTTGTTTTGTTTTGAGA CGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCATTGCAAC CTCCACCTTCAATTCTTCTGTCTCAGCCTTCCGAGTAGCTGGGACTACAGGGGCGTGCCA CCACGCCTGGCTAATTTTTTGAATTTTTAGTAGAGTTGGGGTTTCACCGCGTTAGCCAGG GTGGTCTCGATGTCCTGACTTCGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATT ACAGGCATGAGCCACTGCACCCGGCCAACTGTTAACATTTTACTACATATGCTTTATCAT TCACGCATTCCACACATATATACATGTATGTGTGTACATTTTTTTCTCAGAATTATTTGA TAATAAGTTGCATACATTATGTCACATTTTGCTTCTAAAGAGTTCAGTGAGGCAAGGTGT GGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGAGGGCAGATCACTTGAGT CCAGGAGTTCAAGACCAGTCTGGGCCATCTCTACAAAAAATATAAAAATTAGCCATGCGT GGTGGTGCATGCCTATAGTCCCAGCTACCTGGGATGCTATAGTAGGAGAATCACCTTACC CTTGGAGGCTGAAGTTGCAGTGAGCCCTCCAGCCCGGGTGAGAGAGAGACACGGTCTCAA AAAAAAAAAAAAAAAACCCACTAATGTGAAATACCCATGTGAAAAGGGTATAAGAGCAGC TTTTGAAGGGGCTCTCACTTGCTCCCAATTTGAGGATCAAATGGAATTAGAACAGTAACA GATTATAGCCCATTGAGTAAAATAGGAATCCAAGAGTCCATCCTTATGCTGAATAGATAA ATAGATGAGCGGATTGAGAAATGTGAAAGAAATGGTAGAATTGGAAAAATCACCATTTTG TAGCCATCCCAGTAAAGACAAGAATTGTCTTCCTTTAGGTAAGAATTATCAGTGTATGCT AACCCTGGGAAGAAGAGTTTTGCATGCATTGAGGAGGAGAGAGATTTTGAGAGTTTGATG AGGAGCAGGATATTTGCATATCTCAAGAGGTCTTCCTACTGAGCAGGTATCAATTGCAAT GAGGAAAATAGTGACTATACAGCAGAGACAGTGGACAGTCCAGTTAATGAGAGTTCATCT CACCAATGAGGAGCAAAAGGCCATCATGTGCCTGCAGATGTAGTACCCTAAGAAAGACAC AGCATCACCTGTATAGCATTTCAGTTGAGAATGCACAAGGGAATGTCACACATGCGCAGA TTGAGAAGCATTTTATAATTCTTCAGAAATATCACCATGGCCAGGCTCCATGGCTCACAC CTATAATTCCAGACTTTGGGAGGCTGAGGCAGGAGGATTATTTGAGGCCAGGAGTTCGAG TCCAGTGTGGGCAACATAGCAAGACCCTATCTCTGCAAAAAATTAAAAAAAGAAAGAAAT TAGCCAGGTGTGGTGGTGCATGCCTGTAGTTCCAGCTATTCAGGAGGCAGAGCTGGAAGG ATTGTTTGAGCCCAGGAGTTAGAGGCTGCAGTGAGCTATGATAGCACCACTGCACTCCAA CCTCAGTGACAGAGTGAGATCCTGTCTCTAATTGAACTAAACTAAAAATAAAATAAATAA AATGAAATAAAACCCAAAAACCCCACATATATCATTGCCCTAAATGACAAAGACAGACGG AAGAACTTGTGAACTAACACAGACTAAAGAGACGTGAAAATGGAATGCAGTGCGCAATCT CAGACTGGATCCTGCACAGAAGATGGAAAAAATAATGTCAGAAAAGACTAATTGAGACAA TCAACAGCTTGGAAATGGGTGATAGATGAGATCAAATTAGTTTAGATTTCATTATATCAG TGTTAACTTTCCCAATTTGATGACAGCAAGTGGAAATGTCAGAGAATATGATTATTCTTA GGAAATAAAAAATGAAGTGTTAAGGGGTAAGGGCATGATTCATGCAATCTACTCTCATAT AGTTCAGGGAAAAAATAGTATGTTTTGCATAGAGACAACCACAAAGCACATTTGGCAAAA TATTAAAAATTGATGGATTTGGGTAAAGAATATATGGGAGTTCTCAGTACTATTCTCTCA GCTTTTCTGCAAGTCTGAAATTATTTCAAAATAAAAAGTTAAAGCCAGGTGAAGTGGCTC ACGCTTGTAATCCCATCACTTTGGGAAGCCAAGATGGGCGGATTGCTTGAGCCCAGGAGT TCAAGACCAGCCTGGGCAACATGGCAAAACCCCGTCACTACTAAAAAAATATAAAAATTA GATGGGTGTGGTGGCGTGCACCTGTGGTCCCAGCTACCCTGGAGGCTAAGGCAGGAGGAT TGCTTGAGCCCAGGAGGTCAAGGCTGCAGTGAGCTGAGATCATGCCACACTGCATGCCAG CCTGTGCAACAGAGAAAGACCCTGTCTCAAAAAATAATAATAAAACAAATAATAATAAAA CAATGATAGAATTGTTTACAAATTCTATCATTAAATGGATGGATAAGTGAGATGATAAAG TAAATGTATTAAATTGCTGGCTTTTGTAAAATCTAGGTGGTGAATAAATGCGTGTTTGTA TAATTCTTTCAATATTCTTTATTTTTGAGCATTTTTATAATGAAATATTAAGGGGAAAAA AATCCTGTCTTTTAAAATCACAGTTTATGTGTAGCTGTGCTTAAGTGTTAACAAAAAATT TCTTGTTCTAAAGGGATTAGGTGCTTTATGCTTCAGAAACTATTTTAACCAGACAGCATT GCAGTGTCTTACAATGGTATGCCTTGGAGCATTGTTTATGATGAAGTTTTGAAGTCCTTT ATTAGTTTTTTGCTTGACTGACCTAGTAAGCTGCCTAATTATGAAATGGGCACATAACGT TCTTCATGTTCTGTTTTTAGAACATGAGAGATTTTCTTTGGAAATTATTGAAACAGCAGT TTTTTTAGTGTAAACAAATTGTCAGTACATTTTCTTGATAGCAACCAGAGGTGGAGAGTT CTATTTTATTTAGAAACCGCATCTTCTTGGCTCTCCTGGACCAAGGCCCTGTCAGCCTTT CAGTCTGGACTGTGCATCGCAGAGTGAGGGGCGGTAACCATCAGTATCTGGGCATTTTTG AGGCAGACCTCACAGACTGTGCCACCATCCTTGGGTAATACCTTGGCCTTTAACTCTACC AGCACACTCTGTCCAAATCCTCTCCAGTGAATAATCAAGAAACACAGGGCCACACGATGA TGTAGAATAGGGATTGGCCAACTACAGCCCATAGGCTATATGTAGCCTGCCACTTGTTTT TGTGAATAAAGTTTTATTGGCACAAATTCATTTAATGCACATTCATTTAATGTTGGCAAT GGCTGCTTTTGCACTGCAATAGTGTTGAGTAGTTGTGGTGGACTGTAGGACGTTTATAGA AAAAGTTTGCCCACTATTCAAGGAATAACAATAGCTGACATTAATGGAGAACTTTCTAAA GGCGGGCACTGCACTCAGGACCTTCCACGAACCATTCCATTGAGTCCTTACTGCTTTGAT CTCCAATTCACAGATGAGGAAGCTGAGACTGAGACTCAGTTACTTCCCCAGGACTATGAA GTAGGATGTACAGAGTCATTGGGCAAACTCAGCTTGAGACAGAGCCTACCCTAAGCCCAG TTCACCATTTGTTGAACAATCCAGGCTTACCTTATTGTAGTAATAATTGCAAATTATGAA AGGTGATTGCCTTTTTAAAAAAAAATTTAGGTTTTCCTGAGAGAATGTAAACCAGAAAGA AATTTTTAAAAATTAAGTTTTTAAAAATAATATTTTTGTTTGTTTGTTTTACAGCTTCAG TTAATAATTAAGAAAGTTATTGCCCACTTCCATGACTTCTCAGTTCTTTTCTCAGTGGTA AGTAGGATTTCTTAATTATCTTTGGAAATTTGTACCTGGCTCAGAGGTTCTCATTGTCTC AGTAATGTTTTCATGATGCCCCAGGCCAAAAGAAATATTCAGCAGTTCCTTTTATAAAGT AGTTAAGTCTGATCAACTTAAGTATTTATGTCCTAATAGATTAAGCCGTATTTGAAAAAA TAATACACAAAAACTGAAAGAAAAATATTATTTCTGTTTCATTCCTTACTTATGGGATAT GTATAAGTAAGGGCATTACACAACTTCTCAAACCTTCAAAACACTTTGGACAGCCTTCTC TTACTTTGCTCTTCCACAGTGATTTTCACAGGGCACTTGCTTTTTAATCACACAGCCTAA TGTTGAAACTATGAAATACATTGACTAGTAGTTGTTTCAGTGTCTGACAGTTGAGATTTA CCATGATTCCCTCAAAAATTTAAAATATCCTGCGATGTCTGTTCGAGTTTGTTCAGTGCC CTGGGCAAGTAGGGAATCTAGGTTATTCCCTGTATAGTAACATTCTCTGTCTCTCCCTTC ACTTCCCTCTTCCAGGTTCCATTTACATGTGCTCACAAGATTGTAAGATTTTTTATTTTA ATCATAGCAGCTAATATTTATTCGACATATACCACACTCCAAGCACTGTTCTGGGACTTT ACATGTATTGCCTCACATTAGTTTCATACCACCACGGGGAAGTAGGAGTTATCACTGTAG TATTGCCTTCTTATCCAGGAGGAATATACATTCCAAGACTCCCAGGAGTTGCCTGAAACC GCAGATAGAACTGACTGCTGTGTATACTATGTTTTATCCTATACATACATACCTACGGTA AAGTTTCATATATAAATTAGGCACAGTAAGAGACTGACAACAATAGCTAAAATAGAACAG TTATAACAATATGCCAGCATTGCTACTCTTGCACTTTGGGAGCATCATTAAGTAAAATAA GTGTTCTTTGAACACAAAAATGCTGTGATACCATGACAGTGAATCTGATGACAAAGACAG CTGCTAAGTGACTAACGAGCAGGTAGCATCTACAATGTGGAGACGCTAGACAAAGGGATG ACTCACAACCTGGGAGGGACAGAACAGTATAGCGTGAGATTTCATTACACTACTCTGAGC AATGCACAATTTCAAATGAATGGGGCTGGGCTTAGTGGCTCACACCTGTAAACCCAGCAC TTTCAGAGGCCAAGGCAGGCAGATCACCTGAGACCAGGAGTTCCAGACCAGCCTGGCCAA CATGGCAAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCAGGTGTGGTGGTGCATG CCTGTAGTCCCAGCTACTGGGGAGGCTGAGGTTGCAGTGAACCGAGATTGCACCAGGGCA CTCGAGCCTAGACAACAGAGCGAAACTCTGTTTCAAACAAATAAAATGCAATAAAAATAA AAATGAAAATGAATGAAGTGCTTATTTCTAGAATTTTCTATTTAATATTTTCGGATGGCC GTTAACCGAGGATAACTGACACTATGGAAAGCAAAACCGCAGATAAGGGAGCAACTACCA TATTCCCACTTTACAGATGAGAAAACTGATGCAGGAAGAGGTAGAGTAACTTGCTTACAG CCACACAGTCACCGAGGTTAGTATTCAGAGCCAGGCGGTCCAATTTCGAGGCCATCTGTG AACAGCTCTACTCTGACTCTTCTTCCATTGCTCATCAATATAATCACAAAAAGACTGAAG TCTGCCTTGCCCAGAAAAGCTTGTGGTCATCAAAGGTTGCCTGGATGGCTCACCAAAATG TTAACTGGTCCCAGCACCAATCCCTGGAATGCATATAAGTTGTTTTAATAGTAACAGCTT TTTATTTTGTTTGTTTGTTTATTTTTGAGATAGAGTCTTGCTCTGTCACCCAGGCTAGAG TGCAGTGGAGTGATCTCGGTTCACTGCAACTTCCGCCTTCCCGAGTTCAAGCAGTTCTCC TGCCTCAGCCTTCCAAGTAGCTGGGACTACAGGCATGCATCACCATGCCTGGTTTATTTT TGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGGC CTCAAGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTG TGCCCGGCCCAGTAACAGCTTTTTACAAGCCCAGTCAGGTCCTCTCCCTGATTTCAGAGG AGTCCTCATCTGACCCGACTCAGAGAGATGAACCTCTGTTCTGCTTCTTTGAACTCCACA GAAAAAGAGACCCACAGATTCCTTCCTTCCAATAACTTGTGTCATTTGCATATAGAGTGC TTGCTTTATTTATAGGAAAAATTTCTGCCGTTTCTGGACATGTTCCAAAAAGAGAGTGTG CGGGTGGAGGTTTGCAAATGCATCATGGACGCCTTTATCAAGTGAGTGCCACTGCGTGCA GCAGAAGCCTTGATTCCCAATGTCCTTGTGAAACCTGTTGATAAAAAATCAGTTCTTGCA CTTTGAGGCCGAGTGATGTGTACGTATTTCATACAGAAAACCACACTGGAAGGAAAGCCA CATTAAAAGCAGCAGTCTGATAAAAGTTTGTAATTCGTGTTTAAGAAGACAGAGTAGCAA GTGTTATCATGAGCCTGGCCAGAAAACCACACTGGAAGGAAAGCCACATTAAAAGCAGCA GTCTGATAAAAGTTTGTCATTCGTGTTTAAGAAGACAGAGTAGCAAGTGTAATCATGTGC CTGGCCAGCAGCTCCATTTTACTTTTGATATGTTTTTAGAAGGAGCAGTCTTTTGATAAA TTCCCTCAAGAGTAACATTTTTAAGGATACAAATCAGGACATACATACTTACGAAGAAGG CACCGGTGCTAGAAAGGTTTTCATCTTCAGTGTTTAGTTATGTAGCTGACTAATGTGTGA TCAGTTTTCAAATTTAGCTCTTTAACAAAAAAGAAAAAAAATCAAATTTAGTTCTTTTCA TTTTTTTGATTAAGTCTGTGTTTCCCAAAACTGCCCGACTGCTAGTGGTACATGAAATAA TTTTAAGGTGGTGCATGGAAAAAAGGTGTTTTTGTTTTTGTTTGGAGACAAGTTCTCACT TTGTCATCTAGCCTGGAGTGCAGTGGCACAATTACGGTTCACTGCAGCTTTGACCTTCTC ATGCTCAGGTGATCCTCCCACCTCAGCCTCCCAGGTAGCTGGGACTACAGGTGTGCCCCA CTACAACCCAGCTGATTTTTGCATTTTTTGTAGAGATGAGGTCTCTCTATGTTGCCCAGG CTGGTCTTCATCTCCTGGGCTCAAGCCATCCATCCACCTCAAAGTGCTGGGATTATAGGC GTGAGCCACCTCGCCTAGCTAGGGTTTTATTTTTATTTTATTATTATTTTTTTAATTTAT TTTGAGGCAGAACCCTGCTCTGTCACCCAGGCTCGAGTGAAATGGTGCGATCTCAGCTCA CTGCAGCCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGG GATTATATGCACCCACCTCCACGTCCGGCTAATTTTTTTGTATTTTTTATAGAGACAGGG TTTCGCCATGGTGGCCAGGCTGGTCTCGAGCTCCTGGCCTCAAGTGATCCACCCGCCTCG GCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCGGCCTGTTTTTATTTTT AGAGTTATATATTGATTTTAAATGTATTAGGCAGTTTATAACTAGTTTAATATGATTTCA TTTACAATATATTATTTTTTAGGACAGGGTTAAGAAAAAAAAGCTAGTTACTTTAAATAT TAGGTGTATAGATATGGTTCACTTTGGAAAATTGAGTTTGATATTGCTCAAATGTTTTAA GCTTTTCTTGTCATCTTTCTAAAAGATTAATTCCTTCCTAAGGATTAATATTAATTCCTA ATTAATATGCTTGGAATAAATATACCTAATTTACTTACCTAAAGATTTGTTTTAAGAGCT TGCCCTTTTATATTATTTGAAAAACCAAATGAATAATTTTGCCTGGCAAAATTCGCCTGT TAAGAACACAGTGACAGGTTTTGGGCAGCTTCAGAAGGTATAAGAAGCATAGTTAAAAAC AAACAAACAAAAACAGGTTTGCCCTTAGCCCACCTGGTTTAGGAAGGGGAACAGTTTTTC TGTGATTTTGCAGTTAGGAGAAGTTATCATGTGTATAGAAGAGCAAACTTGTTATTTAAA GAATTCTGGGCCAGGTGCGGTGGCTCACGCCCGTAATCCCAATACTTTGGGAGGCTGAGG CAGGTGGATCACCTGAGGCCAGGAGTTCGAGAGCAGCCTGGCCAACATGGTGAAACCCTG TGTCTACCAAAAATACAAAAATTAGCTGGGTGTGGTGACGCACGTATGTAATCCCAGCTA CTTGGGAGGCTGAGGCAGGAGGATCACTCCAACCCAGGAGGCAGGGGCTGCAGTGAGCTG AGGTCACATCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAGTTTAA AAAAGAATTCTGAGACAACCAGAGAACATGGCTCGTTACTGGTAAACTGGGCTGGGTGAA ATGCCAGCTGGATAATTTGCTGCTTTTCAAGTGTGTACAGTGGATGAAAACTGAATCCAC TCTTGCAGTGCTGTCAGTGGACAAAACTTTGACTTTTATCTTTAAATGTCTCCTAGGCAT CAACAAGAGCCCACCAAGGACCCGGTCATCTTGAATGCCCTTTTGCATGTTTGCAAGACC ATGCATGACTCTGTGAAGTAAGCCATGCTTACAGCTGAAATATAACATGGATTGGGTCTT AATGCCACCTAATAGGACATTAGGGAATGACTGCTTTAAGCTGCCACTGTGAATAATATT ACTTTATTGGGAGTATTAAGATTTTTGCTAACGAGGACATTCCAATCCAGGAGAGGAAGG AGGCTGAGGTTAACCTTCTTGAGAAAGCGACGTGGCAGATGTTGTTAGAAAGGAGTTTAT GTTGCGGGTAAAAAGCTGGTTCCATTCAAGTGAACTCAAACTCCATGTCTCTTGGAGATT TCTGAGAGCAGCAGATAGTGTAATAATGAGCTCACTCATCCAGTAATATAGCCTTTTTAT TTCATCTCTATATTAGCCAATTATTTGAAATTCAAATGAAACTGCTTGAGGCTGAGACCT ATCCACAGGCATTACCTTTCAGTCAAAGGCTGAATAGTCACTGCCTTCTGGTTTTTGTTT GTTTATTTTTAAAATATGTTTTCGTTTGACTGTGCTTAGGGCAATTCCTGCTTATTTGTG GCTGAAATTTTAGTCCCCCAAGAATTTTTAAACACAGCAACTTGATTTACTGGAAAATGT TACAAGAATGGAGAAAATTGTTTTGGAACTTAACCATCAACAAGATGAACTGTATTTCTT CTTTGTTTTCTCTGCATTTTAGAATCTTCACTTCCATGATTTTTTGTGCTTTCAAATTCA TGGGTAGTTACAAAAATCAAAGTGTCGAGGCATTTCATAAAAATGGAACCGGTAGACTTT AGTTGGACAAAAATAGAAATAAAGACACAAAAAGCATCCAGAAAGGCACTTAGATTCGTG AGACATTGGGTTTTGGCTTAAGTAAAATAGAATGTTGATTTCTCTCTTGTTAAAATTGTG CATAGTAGACAGACCAGAAGGTAGGGGTAGGGCAGCTCTTCTTTCAAACATCATCCAGGG ACCCAGGTTATTTCTGTCTTATTGTTCTCCCAGTCTATCTGGGGTGTTGTCCTTATCTTC TTCCTGGAAGCTGATGTACCTCAACCATGTCCACGTTCCAGCCTGTGGGCATTGGGGAAC AGCAGCTTTCTTTTAGGGACAAAGCTGGGAAGGCTCACACATCATATCCCATTGTTCAGA ACTGTCCCATAGCCACCCCTAGCTGGGAAGGAGGCTAGGGAATGTTGTTCTAAGAACAAA GTGGGGCTGGGCATGGTGTCTCACACCTGTAATCCCAGCACTTTAAGAGGCCAAGATGAG TGGATCACCTGAGGTCAGGAGTTTGAGATCAGCCTGGCCAACATGGTGAAACCCCGTCTC TACTTTAAAAAAAAAAAAAATACAAAAAATTAGCTGGGCGCCTTGGAACGTGCCTGTAAT CCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGCACAGGTTGCA GTGATCCAAGATCATGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCATCTCA AAACAAAAACAAAAACAAAAAAGAACGAAGTGGGCATTTGTATTGAAGGACAGTGGGCAA TCTTTGCCAAAACATTTTCTCCGAGAACAAACCAACAAACAAAAACCTTGACTCCTGTTT TCTCTGGGCTCTTAAAAATTTTTTTTTTAAATAACTTTGGGGAACTATTTATTCCCCAAA TAACTATTTATTTAACTATCCAAGTATAATCAAAACTGTAATGACTTTTTCTTATTTATA TTTGTGTTACATTTTCTATTAAATAGAAGCAACTGAGACCTGAGATTTACTTTACAATGT ATCAAAAAAATAAGATGGATTGATGGATGGAGAGGGGAATGGATAATTATGTGTAAAACA AGTAAAATGGTGATGGCAGGATTTCGATGGTGTATGGGTGTTTACTGGAAAATTCTTTCA ACTTTGCTGTACATTGGAAATATTTCTGTTTCCTTTTTGGGGAGAACGGGGTCTCGTCAT GTTGCCCAGGTTGATCTCCAACTCCTAGGCTCAAACGAACCTGCTACCTCTGCCTTCCTA AGTGCTGGGATTACAGGTGTGAACCAGCACACCCCGCTGGAGATTTTTTAAATAAAATAT TCAATGAAATTTCCCTGAAATACAAAATTTGACATTAGACCTTGCTGCCCAAGTTCCAAA GAAGTGAAAGTTACCTTTTCTTTTCTTGTTAATAAATCTATCTTGAGAACAGCATATTTG AGGGAGATGAGAAACATATTTAAATTATGTTAATTGTGATTATGTATTTTTATCAAAGGA AAAATAAGCAGCCTGTTGGCAGTTTTTTAAATCTAGAAAATGCAAAATGTTCTTACCTGT TAAATTACTTACCCCTTGTGTATTTTTTTCTTTAGAAACTTTCATCTATTACCTCCGTGT TAATTATGTACAATTATTGATTTTAGTGCACTCACTCTTGAGGATGAGAAAAGAATGCTG TCATATTTGATTAATGGATTTATAAAAATGGTAAGTATTAGGGAAGAAGTTTCAGTGCAC TTGGAAGTGTGATGTAATTGTTTATCCTTATGTTGGCGAAAGCAGTTAACATTATGTTCT CTGGTGCTTTTCATTCTTAGTGAGATAAAATGAAATTAGAAAACATCTTACATTAGCCAG GACTCCCCTGGGGGCAAAGAGAGCCAAGACAAACTGGCTTAAGAGGAAAAAGGTGGGGGG CGGGAGGGTGATGGGAGGAGGGATTTCTTGGCTCATGTGACAAAAAGTCCAGGGGCTGGA ACTCTCCAAAGCAGCAGCCGGGCTCAGGGTCTCCGGGATGTCATCAGGACCTGCCTTCCC TGTCTTTTTTCTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTGG AGTGCAGTGGCGCGATCTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTC CTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGGCACCACGCCCGGCTAATTT TTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTGCTG ACCTCGTAATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTG CACCCAGCCCCCTGTCTGTCTTTAGCCCTGGGCTCTGCCCTGTTGGCCTCCGGCTCAGCT GGGCTTGCCCCACCAGAGCTCCAGGTTTCCATCCCCCCCAGCTCTGCAGCCCAGCAGGTG GGATTCCAGCAAAGTCCTGGGATTGAGTCTCTTTGGATTAACATGGGTCGTGGCCCCAAG CACACCTGGGTGACCTGAGTCAGGAGGGCCGAGAGTGGAAAGAAGGTGTGTCCTGAAGCA GCTGATGCAGATCATCAGACGGTGATGGAAACTATGCCGGGCAGGCAAAACGCCAGATAT CCACTCCCCATCTGTTTTACTTATCTACTGCTGAGTAACAGCTCATCCCAAAACTTAGTG GCTTTAAATAACAGGGCTTTTTTTTGCTGTTTTTTTTGGGGGGGTCGAGACAGGGGTTTC CAACTCCTGGTTTCAAACAATCCTCCAGCCTTGGCCTCCCACAGTGTTGGGATTACAGGC CTGAGCCACTGCGCCCAGCATGAGTTTTTTATTAGTTCTCAAACTCTGCGGATCAGCTTG GTAACCAGGCTGCTACAGGGAGTGTGGTGTGGCACTGGCGTGGCACGATTGGGCTGGAGG ATCCACAGTGGCCTTGTTCCCTTCTCCAGGGTTTTGGTGCTGGATATGGGCTGGGGCATC TTGGTTTTCTTCCATGTCCTCTCTTTCTCACCACTGTTCTCAGTCAGTGATTCCAGTTGA GCTCTCTTACTTGGTGCTGCCTTCTATGAAGGCACAGACAGAAGCAGCAAGGCATTTTAA GGCCAAGGCTTAGAAATCACACAGTGAGGCCAGGCGCGGTGGCTCACATCTGTAATCCCA GCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGCGGTCAGGTCGAGACCAGCCTCACCA ACATGGTGAAACCCTGTCTCTGCTAAAAATACAAAATTAGCCGGGTGTTGTGGTGCATGC CTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGA GGTTGCGGTGAGCCAAGACCATGCCACTGCACTCCAGCCTGGGCAACAGAGCAAAACTCT GTCTTGGGAAAAAAAAAAAAGAAATCACACAGTAAACCCCTGCCATATTCTACTGCAATC TGTGGGTCAAAGCAAATCACAGTCTTGAGGGGACCCAGTCTGGAGGGGAAGAGGCTCTGC CTTTTGATGGGGGGTAGTCCACAGAGACATTGCAGAAGGGCAAGCACAGTGGGAAGGTTT CCTGCAGCCTCCTTTGGGAACATCCCACCATTATACTATCCCAGCCTGAACAGTCTTCAC CTTCATTCTGGGTGCTCTAAGCCAAAACACCAACTGCTGCAAATATCTTCTATTTTAATA GAAAAGTCAGGACCAAAGCTGACTGAGATGAAAATGACGAGATCACTTTGAAAATAACCT TGAAATTCTGACTTGTTCAATAGTGCGGGTTGATTAGTCTACCTGACTCTGCGGGTAAAA TATCAATTTTGATGAAAATTCAGGATTAGCCTTTCAATTCCCGTGTTAGGAAACAGACAT ATGGATTTTCCCAAGTCGCTCTCCTTTGCCCTTGCTTTTTGTACTCATCATGTGGTATTT ATCTTTTTACGGCATTGTCTGAAAGTTACCAAGTTATTATGGAAAAGAATATAAGGAAAT CAGATATGAAACATGATAGCTGTAATGGAAATGGCAATGTTAAACCTCATCTGGACAAAA ATGATTGATGTACAGTAAAGTTTTTCTTACTAACCAGCTATTCATAAATTTGAAGAAATA GGAGAAGAGAGGATGTTTAATGGTGGAAAAACTTCCATCTATGGCTTCTGTAGCCACCAG TGAGCTGCCAAGGTTGGGTCCCCATCAGGAAGCAGAAAGGTGTGACTGTTACGATGGCAA ACCTTCTGACAAGGGGCCCCCAATAACCACATTTATGTTCTGTGAAAAGGCCACAGCTGA CAAACAATATCCCATTATTCCCTTTCCAGTGGTTTCCTTCAGAGTCTGGAAAATTCTGCT TACACTCTGAGCTTCTGTTTTATACCCTTCGACTTCTTAGGTTCTAGTCCAGTGCCCACG TCATAAAGATGAGGTGGCAATAATAATATTTCAGTCATACCATGTGCCTGCGTTCTCTCT AAAAATACCACTGTCCCTTTCAGCGTCTTTCTCCTTGATTCTAGGTTTCCTTTGGCCGTG ATTTTGAACAACAGCTGAGTTTTTATGTTGAGTCCAGGTCGATGTTTTGCAATCTGGAGC CTGTTCTTGTGCAGTTGATTCATGTAAGTATTTTCATTCATTAGTTTCTTCTCTCAGTAA ATATTTATTGATCATCTACATCCCAATCATTTATTTTGATTTTATTTTATTAGAGACAGG GTCTCACTCTGTCACCCAGGCTAGAGTGCAGTGGCGCAATCATAGCTCACTGTAGCCTTG AACTCCTGGGCTCAAGCAATTCTCCCTGTCTCAGCCTCCTGAGTAGCTGGGACTACCAGC TCAAGCCACGATGCCCAGCTATTTTAAATTTTGTTTTGTGTTGTTTTTTGAGAGATGGGG TCTCTGTGTTGCCCAGGCTGGTCTCAAATTCCTCACATCCAGCATTCCTCCTGCCTTGGC CTCCCAAAATGCTGGGATTACAGGAAAGAACCACTGCGCCCACCCTTAATCTGGGTTTTT TCTGGTCCTATTTTGTTACTCTTCTCTATGGTATGAAAGGTGGTTTCTCAAAGGTTAATA AACTTACAACTTTGGTTTTATTGATCTGTTTTTCTGTGAGATTTGCATTTTCCCATTTCT GCCTGCCAGCAACAGAGGTAAGTGATTTACAATGATTAGTTACAGAAATCTAACCAGAAG GAGCCCCTTCTTACGTAACAAGAGGTTCCCTACTTTCTTGGATCATGGCAACTCTCAGTA ACTTTTTATGGTGCCCTCAGACCAAAAGAATTAATAACAGCCCTGTTTATTAAGAAGTTA GGTTCAGGCTGGATGTGATGGCTCACACCTGTAATCCCAGCACTTTGGGAGTCTGAGGCT AGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGCCCAATATGGTGAAATGCTGTC TCTACTAAAAATACCAAAGTTAGTCAGGCGGGGTGGCAGGCACCTGTTGTCCCAGCTACT TGGGAGTCTGAGGCAGAAGAATCGCTTAAATCTGGGAGGTGGAGGTTGCAGTAAGCAGAG ATCGCGCCACTGCACTCTACACTCTAGCCTAGGCAACAAAGGGAGACTCCATCTCAAAAA AAAAAAAAAAAAAAAAAGTTAGGTTCAGACAACTTAAGTATTTATGTCTAACAACTTGAC AGCCATTTGAAGAAAGTATATATATAAATTGAAAGAAAAATAATACTTTTTTTTCCTTTT CTTTTTGAGCTGGAGTTCTTGCTTTGTTGCCCAGGCTAGAGTGCAATGGTGCGATTTTGG CTCACTGCAACCTCCACCTCCCGGGTTCAAGTGATTCTCTTGCCTCAGCCTCCCGAGTAG CTATAATTACAGGCACCTGCCACCATGCCCGGCTAATTCTTTGTATTTTTTAGTAGAGAT GAGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCTTAACCTAAGGTGATCCACCTGC CTCGGCGTCCCAAAGTGCTAGGATTACAGGCATAAACATCAAGCCCTGCCAATTTTTTTC TTAACCATAATTAGTAATGATGGGTGTGTACTTATGAAGCATATCACAGCTTCATAAAAT TTTGGAGTTAGATTGGTGATGCTATTCTTATTTCTTGTTTTACATTCACTGTTTTTTACA TTTATTCTTGCACAGCGATTAAACTTGCTTTTGATCACAGTAGCCACGAAAAACAAGTTT TACAAATATATGATGTGGCTATAAGGGATGTAAAGCAGTCCATCATCAAATCAGCCTTGC ACCAGTGCTTTTTACAACGTGCAACAAACAAGTATTGCTGTTTACAATGTGCGACAAACA AATATTCCCTAAAAAACGGTGGCGCCCCTGTGAGTTTGCTGCAGCACCCCAGGGTGCCAT GGTGCACCGTTTGGGAACCACAGGTCCAAACTTTTTATATCTGTGGAAGGGTTCCCTAAG GCTCTTTCATTATTTCATGTCTATTCAAGGAGAATAACTTTCATATGTATTTGTTTGCTG GTTAGCAAGTTATTTAGCACAACTAAACTTAAGACCTAAATTTAGAAACTATCTGGAAAT CAGGGGAGGTAATAGTATCCACCCTGGGATTATGAAGCTTAAGTGAACCAATGAATGTAT AGCTCTTAAATAGTGCTTGGAACACTATTAGTGATGATGTGGCTACTATCATTATTGTTC TTATTGTTGGTACTGTATAGCTGAATGGTGTGGTCTGATTGTCTAAATGGTGTGCTTTGG AGTTGTCTCTTAAGATTTCTAAATTCTTAAACTTTGGTGTGGTAGGATTTCTGGAAATGG AGTAAGTGAGCCCCAGCTATTCATTAAGCCAGAAAATGGTCACTAAAATGCTGATCAAAA GGCATGACTGACGTAGCCAACACTGCCTTTTGTTCTACCCTCTTGGAGATGTTTGCTCAA GCCATGATTGGATCAGGCCTGATGACCCCTTTGGCATTTCAAGGTTTAGTGCTAACCAGT CTTGGTCCTAGAAAGCTTGTTCTCATTGACCTGTATGTAGTTAATGTTGAGATCTCTATG GAAGACACTCATCTGAATCGGCCATCGCTTCATTACCATTTCTATTTTATTAATAAATTC AGAGTGTGAACCGGTTGGCAATGGAGACAAGAAAAGTAATGAAAGGAAATCATTCCAGAA AGACAGCTGCATTTGTCCGGGTATGTTCTTAAGATAAGGACTGTTGGACCTCGAACTCCA GTGGGCTGTTTAGTTTGCAGGTTACTAAATTACATTTCCCAGAAAAAGATGAGTATGTCA TGATAAGAATGGTTTAGTATTGATTTTTCAGATTAATTTTTCCCTGTATCTATGGGATGA GCCATTTTCTAATGTTTTCAAGAGAAATGGTTAAATGAGTCTGAATTTTAATACGTGTTG TGGGGAAGGTGAATGAGCGATGGATCTGCATTTTTATGTGCCAGCTGAATTAGCTTTCAT TTTCTCTAATATACTAATATAAGACATATTTTATAACATTATAAAATATAAAATAGTTTT CTAATATAAAAATATGTATAATAATATTGTTCTTGTAACTGAAAGGCCTTTTTTCCTCTA GATAATAATGATGCCCAACTTTGTTTTTGTTTTTCTTGAGACGGAGTCTTGCTCTGTCAC CCAGGCTGGAGTGCAGTGACGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAAGTTCAA GCGATTCTCCTACCTCAACCTCCTGAGTAGCTGGGATTACAGACGCGTGCCACCATGCCC AGCTAATATTTTTGTATTTTTAGTAGAGATGGGGGTTTCACCATGTTGGCCAGGCTGGTT TCGAACTCCTGTCCTCAAGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAG GCGTGAGCCACCACACCTGGCCTGATGTTAAACTTTGAAAAATCATTTTCAGCTTCTTGA AGCTGAAAATTTTATCAGATGTGATGCTGCTCAAAATTTATTTAGCTATTCATTCATTTA TTTATTTTTGGAGACAGGGTCTTGCTCTGTCACCCAGGCAGGAGTGCCGTGGCACCATCA TAGCTCACTGTAACCACCATATCCGGGTAATTTTTTTGTTTTTTGTAGAGATGGGGCATA TCACTAGGTTGCCCAGGCTGGTCTTGAACTCCTGGCCTCAAGTGATCCTCCTGCCTCAGC CTCCCAAAGTGTTGGGATAACAGGTGTGAGCCACCGCACCCAGCCCTGCTCAGAATTTTA AGAAAGAAATATGTGTCTGTGTTTTTAAACATGAAATTATACTGAAAAGATTACAGTAAA AAATAAGCATCCTGGCTCTGCCCTTTGTCACCTTGCTTCTCTTTCCTCAGTTAGCCACCT CAAACTCTTTAGCAACTGTTTCTAATTACCTCCATATTTTTAAGCAATTGGTTTAAACAG CTGTCTCTCAATTTATCAATGTTAGGTGTTACGTATTTACTTCCCGTGATGGTGGGTGAG GATTTGTTTTTCCTGCATTATCACTCACTCCCCTCACACCCCTGTCCTCCTAGAGGGTCA TCAGAGCAGAGTTGTACAAGAGGGGAAAATGGGGCTCAGAATGTGGAGATTCACTGTTGT AAGTTTCTTTCCTTGGAAATACATGAGGGATGAAAACAGGAGTATGATTCTGCCACCGTT GCACTGCTAGCGTTAATGTTTCTTCCCTTCTCCTAGGCCTGTGTTGCCTACTGCTTCATC ACCATCCCCTCCCTGGCGGGCATCTTCACACGTCTCAATCTCTACCTGCATTCTGGTCAG GTGGCCTTGGCCAACCAGTGCCTCTCCCAAGGTAAGTCCATCATTCTCTCATCTCGGGCA CTCCCTTGCTGCTTAGGAAAACTGACTCAGGTGTGTGCGTATGTGTGTAGAGAGAGACAA AGATTTCTTTTTTTAGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAATGTAGTAGTGC AATCATAGTTTCCTGTAACCTCGAACTCCTGGGCTCAAGCAGTCCTCCTGAGTAGCTGGG ACTGCAGGCGCACACCACCACACACAGCTAATGTTTTTATTTTTATTTTTTATAGAGATG GAGTTTCGTTTTGTTGCCTGGGCCTGTCTTGAACTCCTGGGCTCAAATGTTCCTGCTTCC CACCTGGGCTCAAATGATCCTCCCAAAGTGCTGGGGTTACAGGCCTGAACCACTGTGCTC AACCAAGAGAGATTCCTTTAAGGAGGAAAGAAAAAAAAAGATGAATAAATGATGAGTTTT AAATTTGTTTCTCCGCTAGGAAGCACATTGGACACATATGCATTTATAGAGTCAGACAGA TCATAGAGCACAGATAGCTTCCTGTAAGAACCTTCTTAAATCTGTCTAGGACAGACCGGG TCATGCAGCTCAGACATCCTGAGCTCAGCACACCTGGAGAAAGTGAGACATGAGGACTGC TTCACAGTGGTAGATTCATGTTTGTTTGTTGTTGTTGTGGATGTTTGTGTGTTTGAAACC CCAGAAACACACAAGTACCATCTAATCTGTGATAGAACAAATACCCTACAGTTTGCTGTT ACAGATAGTTTCTGCCCAAGACTGGTCTTTCCGTACTAGACACCAAAGCCATCCATTAGG CAAGGATGCTCAGGATCATTTATTTGGGAGAAGGTGATCTCAGTGATATCAGAAGAGTGA TGTGAGATGAGACAGGGAAGGAAAGGAAGCCAGAAAAATAGGAACCATTGAACAGGTCGT TCCTGTGGGCAGCTGAAGCTCATTCCCATCTGGGAGGTGTTGTCAGACAGCCAGTGTTTC TCCATCTGAAGGGCAAGGAAGACAGGTGATTTTCCCTTTATTCTCATCTGTCATTGACAG AGTGCTGCTTCTAGGATATTAACCCCCTGGCATTCTGGCCTGCTCCACACTTGAGCCAAG AGAAGGCACTCAGGTGGAAAGCCCAAGTGTTTGCTGCAGGACACCCTGGTTACCTACTGC AACGGTGTACGCCAAGGGCCTGCAGGCAGGTTAGCAACAGGGTACCCACCCTGCAGGCCG TAACACAGAGGGTAAAAGAAATCTTTACGCGACATTTATGGAGTGTTTGTTATGTGGCAA GCCCTTTGCACAAGTTATCTCATTTCATCCTCCCAGAAGCCACATGGGGCCGGTGCTGTG GCTGGTGCCTTATTACCCAGGTGAGTAAACTGAGGGAGAGAGTGGCCAACTAACTTGCTT GGGGTAGATCCACTCCTGAGTCACTGAACCAGCTCTCAGCCCCTGATCTGTCTGGCTCAA GGCCATGCCCCTTCACCACTGCATTGACTGGGAAGCCTAAAGGAATGCCGGGGCAGTTCC ATAGCGCCATAGGAGGTGGACTGAGGTTTTCAGTGGTGGTTCTTTTCCTGACACAACTGC ACAGATTATGCCAAGGCTGGCGCCTCACCACTTGTTGCCATTGTCTTCGTAGGGCATTCT GGGCCAATTGGAGAGTGATCACTTCTCCATTCTTTGAACCACTGCCATGGAAGTTTTGGG GATCATCTGTGTCATGATTCAACTGGAGCAGCTCTGGGCAGTGAAGTCTTCATACATGGT TACTGCCCAGGAACCTTTAAAACTCGGCTTGGTTTTGCTTCTAACTCATGGGGGACTTCA GTAGCTTCTGAGTGCAGCTGAACACTTGCCTCTTGATTTCCCCTGTGAGCTGGTGCCTGC CCACCTCCATCCTCAACCACCTGCATCCTCATCTCCCATTTGCTTTAGTCACACAGGCCT GCTTCTGTTCTTTGAACACACTCAGTGGTCTCCCAGTTCAGAGCCTTTGTGGCTTTTTTC CCTCTTTCTACAATGATCTTTCCCCAGATAGTTGTATTTTTTTTGAATTACAAGGCAGAT GGTGAGAACAAGCCACAGCTCCTTACGGAGGCCTCTGCTGGCCACTCTAGCTAGAGTAGC CGCCCTGCCCTACTCTGTCACCCCTGCAGCATCAACCTCATTATCATTGTTGCACACTCC ACAATCCGATGCTTTCTTACTGTGTTTGTTTACTTGCTTATTGTCTCTGATACCCCCTCT CCCCACTAGGACAGGCACGTGTCCTCACTAGGACAGGCACGTGTCTTCATTGTGTGTAGG TCAACATGGAACTTTCTCCTACTGCTTGCTTTGGTAAGAATGATGGGTTATCGGGAGGCT GAGGCACAACAATCGCATGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCACCA CTTGAGCAACAGAGCAAGACTGTCTTGAAAAAAAAAAAAAGAAAGAAACAACAATGGGTT AGTGAGAAACAAAACAAAAATTAACAGTCACCACCAAAAACCTAGTGATGCACAGGATGA AAATTAGAAGACGCTTCCTTGGATATTAGAAATTTTAAATCTGCTTATAAATGGGTTCCT TCTTTAAAAGCTCAGGAATGGTGGACCTAGGTAGGCACACCTGAGTTGGTTTTACCTGCA ATACTAGGAACAAATTGTGAGCTGCAGATACCAAAGCTATGACACCACTTACCAGAACTG CAAGGGGAGGCTTTAGAAGCCTAGATCTTTCTTCTTCCCATGTTATAAAATCAGGACCAT GGATCTGAATGTTGTGGATCTTGGGAAATTTATAATTAGATCCCATGTAGGGCTTTATGA TAATTTTTTTTGAAAAAGCAAAACAAAAATTCTCTACCTGGATAAAGGTATCCCCCTTAT CAAAGATTTGGTGCTCCCAAGAACTGTTGAAGGAGAGCTGTAAGTAGTTTCTCCCTGTTG TGCTTCCTATAACGTCCTCGGTCCCCACTGAGGGACAACTGGTGTGAGAACAGCCCCATA TACTGTGCATGGATAAAGACAGCATCCTCGGTGTCAGGACTCTGGGCTCCTTGTCTGTCT CCCCTGTCACTTTTCAGCTACTGCAGGAGAGTGGGAATGTGGAGTCCACTTCATGTTTAA TAATTTATCTGATGATTTTTACTCAAGTCTCTAAATGCTGTGGCGCTAAACCTTAAAAGC CTATTATTTTTCTCCTGAAAGCCACAGGCAGCAATTGCTGGCCAAAATAAATAATGCATT CAATTACTGAGAATGAGAAGGCTAAATATAAATTAAATGAAGCTCATGGAAATGCGCTGC TTTTGTTTGCCTCCCTAAACATCCTCCCCTTGCAGCTGGTTATAAAATGTCCCCGTCCCT CCAGTTCATTTTGTTGCCTCCCTTAATCCGGCCTTGGTTGTATCTTCTTTGGCAGGCTGT GGCTTTCCCAAGGCTGGGTCCATCCCGACAAGTAAACTCCTGTTGAACCCTCAGGCAGGC TGGCGCAGGATGCTGATGAGGGCTTGTTGCAGGGGAGGCCTGGTTCTGTTCCTTTGTACA CACCGGTGCTGTGCATAGACTGGATTGTGCAGGGATTTGGCACGCATGCTTGTGCCCACC ACCCCAGAGTATTTAGGAGAAATGAAGGACTTGCAAGCTAGAGATTTGGTCGATCAGATG CTTCTTAACTGGAGATGGCCTAGCAATGTCTCTCTTTTCTTTCAGTCCCTTCTCTAGGTA ACTTCTTGCCCTTGTTTGTCAATGGCTCTTTCTAGAAAATTATTTCCAGGCCACAGCAAG AGCAGGTTCTTTTCTCCTTTATTTTTACCTTTGTTTCTTTATCTTTACAGTTTATAATCT AGAAAAGGTACGTGTTTTACGGGCTAGGCGTGGTGGCTTATGCCCATAATCCCAGCACTT TGGGAGGTTGAGGTGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACA TGGTGAAACCCCGTCTCTACTAAAAATTAAAAAAATTAGGCAGTTGTGGTGGTGTACTCC TGTAATTCCAGCTATTCAGGAGGCTGAGGCACGAGAATCGCTTGAACCCAGGAGGCAGAG GTTACAGTGAGTCAAGATATCACCACTGCACTCCAGCCTGGGCAACAAAGCGAGACTCTG TCTCAAAAAAAAAAAAAAAAAAGAAAGAAAAAAGAAAATGGGGGCATTTTACAATGGAAG TATGTTTAAGGTGGGTCTTAAAAGAAGAACATGTGTTTATGAGAACATGGGAAGGGAAGA AGGAAGGATTAGCATTCCTGGTTGAGTAAATGGCCTGAGCAAAGGCATGGAGATGTGGAA TTACATGATGTATTTGGCCAACAGCAGAATGTTGGGATGAGGCCCTAATTAGTACTGACT TTCAAGTCTTCTGCTTGCATTGGTCCCAGTCCTGACTCTGCCACCTACAAGCCAGGTGCT CTTGGATGACTCGGCCTTTCTGTCCTGTTTCCCCATCTGTAAAGTGGAGACGATGACAGT GGTACCTATCTGTTGAGTGTTAAATGAGAAAATGGCCTTAGAGCACTTGGCCCACCGGCA CATAGTAGCTGCTTAGTAAGTATTATCTTAGTATAAACATCTCTCAAATGATGAAAGTAT GCCATGGGTTTTAGGAGCTAACTGTATACAGTACGTTGAGAGCTGTTTGATTTTATAGTT AGAAAGCCAGATTATTTTTCATATGCAAAGCATTGGGGAAGCTGTAGGAAACTTAATCTT TGTTTTGAGACAAACTGATGAATTATGCTAAAAAGACTTGCGGTTCCTCCAAAGCTGAAA CAAGATAGAACAATTAAAGAGAGATAGTGGTCAAAAGAACTTGTTTTTTTTTTTTTTTTT TTTTGAGGCAGAGTCCTGCTCCGTCGTCCAGGCTGGACTGCAGTGGCGTGATCTCTGCTC GCTGCAACCTCCGTCTCCCAAGTTCAAGTGATTTTCCTGCTTCAGCCTCCCAAATAGCTG GGACTACAGGCGTGCACCACCACACCGGGCTAATTTTTGTATTTTTTAGTAGAAATGGGG TTTTACCATGTTGGCCAGGCTGGTCTCAAACTCCTGAACTCTGGTGATCCACCTGCCTCA GCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCGTGCCCAACCAAGAATGATTTTA TTATCATTAATAATCATGCTTTTCCCACCTTCTGTAGGGATCTCCCCTGTTCTTTTAGAA CTTACTTTCTTTTATTTTTTGCATCTTCATCCTTCAGAGCTGGGTTCATATGTCATGTCT TTAGAAAAACCATCCTTGGCCTTCCCATTTCTGCAGATAAACAGAAAGTTAGGTCAGGTC ATCCTGTACGATATATTATCCGCTCACCTGTGCTTTTTCTCCATTATGCTTATCACTGTT ATTTAACAAGTAAATATGTAAGTAGTTGTCTGCTTTTCCCCCTGTAAGCGCATCACCTCC ATGAGGTCCTGTCTGTCTGGTTTACTCAAAAAGTTTGAGATTTTGGAGCACTTTGGATTT CAGATGAGGAATGTTCAACCTGTATATGGAGCCCCTGGCTACCACAAACTGTAATGGCTA ATGGAAATAGCCAGGGCCATGATGTGGGAGAGAAAAATTATTTTGCATTTCCTCTTCCTG GAGAGTCAAGAATGGCTTGTGAAGGAGAAAAATAGTTTTCACACATTTACCAGGTCTTGG CGATTTATGTTTAAGTTCCTATTTAGTTTAGTTAACAGAACATCCTTTGAAGAGTGTTTG ATTTGATTGTTTTCTCCAACCCTGAGGCCTCTTTGGTGAATGCAGACAAAGTAGGTTATT TTAGTTGGAACAGTTCACAGCAGGGCAGATGGCATCAAGCTTGTCGCCCACGTTCACATC TGTCCACACATGATCCATCCATCTTAGGGAGTGTCAAGGCCTGGGAAGGATGGCAGCTGC TCATGGAACCCACAGAAAAAGGGCACGGGCAAGTCTCCTCCTGACAATCCCTCAGACCCT TATAATAGTTAAATTATAACCTGCAGTTTCTTCCTCCTGTCAGTATTTTCTGGTCATCTT TTACATGCGGCCCACTGTGCCAAGCATTGTATGGGCAACAGGAATGCACTTAAAGAGACT ACAGGCTGGGCTGGGCGCGGTGGCTCAGACCTGTAATCCCAGCACTTTGGGAGGCCGAAG TGGATGGATCATTTGAGGTCAAGAGTTCAAGACCAGCCTGGCCAACATGATGAAACCTCG TCTCTACTAAAAATACAAAAATTAGCCGGCAGTAGTGGTGTGTGCCTGTAATCCCAGCTA CTTGGGAGGCTGAGGCAGGAGAATCGCTTGAGCCTGGAGGGCAGAGGTTGCAGTGAGCCA AGATCGCACCACTGTCTCCAGCCTGGGCAACAGGGTGAGACCGTGTCTCAAAACAAAACA AGAAAAAGAGACGACAGGCCATTCAGGGAGAGCAAATCTGTTTACAATTATTACACTAGG CGACACATGATAAAGCTCATGCACTATGGACATAAAATGTGCTTGGGAATTTTAGAGCAG AGAGAATTAACCCTTGACTTGAAAGAGGAAAAAAAAAAAGAGGTGGCATTGAAGAGCCTG GAAGGTCAGGGAATATCTTGTTATTATACTGAAGTAAGGTGTATGGCATTCTAGGTTGAG GCCTGGAGGCTGAGAAAACAGTACGTCTGGAAGGAATGAGGAGGAGATCAAGTTAAGGTG ATAGTTGAGGGCCTAATTGTTGAGAGGTCTGAACTCCTGGCAAAATAGTTTTATTCAGTA CGTATTATTAGGTAGGTGGTTTATCTTTATTTTGCAGCTGGAGAAACTGAGGCTCAGGCG TGCTCAGGAACATCCAGCTAATGAGTGGCCTTATCTGGATTTAACCACTGTGCCTCTCTA TATTAGGTTAGTTCTTCTATATCATAACATAGGGTTGTATTTCTAATCCCAAGTGCACGT GGTTGCTGGAGGTCAATTATTACGGATTGAGCATTAGATAAACTAGGAAACAAAGAACCA AAATTAAGATAAGGAATACCTAATCCTTTCTGCTTAGGGAAATCTAAGCCTACTTTTCAC AGAGACAATACGCAACCTCAAATGAGCTACTGCATGGATGAGAGAAAGGTATGTCATCCT GTAGTATCTCCGAGGTAGGAGTTAGGTAACACATGGGCTGAGCATGCTTGGCTCAGTGAG AGAGCCCTTGACAGTTCAGAGAGTAGAGGGAGGGAGAGAGTGCAGGAGCCTTCTGATGGT ACTACCGAAGCTAAGAAGTAATTTATATGTCCCAAGTGGATTTTTCACATTAAGTGTTGA TATTCAGAATGAACTTAAAAGGCATTCTGCATAAACCAGGTGGCAAAATCAAAGTTAGAT TAAGCCATCATTGATAGCAATTAAGCATTAATGTATAAGGTATTTAATTGTTCCTGGAGA TTCATATTTCTTTACATCTTGCTTTATGTACATATCAAAATAGTGGCCCCTAAGTCCTCA AACTTAGCTGTTGGAATAACAAGTTCTATTACAAAAACACAGGCTAGTAATAGATAGTGG TAAATCTCTATCAGTGACTTGCCTGTGGATAACTTGGCCACTGAGACCACAAGGCTTTGC CAAAGGCACCCCATCACTTGGTGGCAGCACATCTTCATTGCAGGCAAAGTTTTCAGGAAG AAGATATGTCTGGATGTTGCATTTTATGTGGTAGTTTCCATGATATTGATATTGTCAATC CAAACCTAAACTCATACGGAGATAGAAAATGTTGAAGATGGGTAAAGATGTTTTGCAATG GGGTTTGTATACCTTGAGAGAGAGTGATGATTTTTATAGCCAGAACCCTGCTTTACTAAT ACACATTCAAGAGATGGGAGTCTTCAACCCTTGGAACATCTTGTCTTAAGAACTTACGAT TTTTGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGT GGATCACTAGAGGCTAGGAGTTCGAGACCAGCCCGGCCAACATGACAAAACCCTGTCTCT ACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGTGCGCCTGTAGTCCCAGCTACTCGG GAGGCTAACAAGGCACGAGAATTGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCATG ATTGCACCACTGCACTCCAGCCTGGGCAACAGAGTGTGACCCTGTCTCAAAAAAAAAAAA AATAAAGAAGAAATAATGGTTTTTCTATTCTTCGATCTTCCTGGGCTAGGACAGCTGTCA GTCTGAGTTTCCTGAGTTACCTAGGAGGGTAGTTGGATTGATGGATTGATGGATTGAAGA TCTAGGAGTGAAATGAATTAACTTTGAGGTTTTGTTCAGCCTCAGGAGTTTATGACTGAC GAGTGGTAAAGATTTCCATTAGCACTGACCTAATGCATTATTGAAAAAAAGCAAAATGCC AATTTTGAAGGTGGGATGGGTTATCACTTCTTGACTGTCACTTATGATTCATGTATTGAC TCATTTTCCATATCACCAATGCCAACCATACAAAAGGTTGCATTTACTCTTGTAGGTCCT AGTTAAGTCTGAATTCCTTTTATCATGTATTGAGGGTGTTTGGTGAGATTGTCCTGTATC CAGTTGAAAATCTAGGCAATCTGTATTTTAAATCTTAATGACTTTCACTATAAAAATTCA GAATGCTCATTTGAAAAACTTCCAACCATACAGAAATGTAGGACTCTTAAAAAGTAAAAA GCCCTGAGATAAAAGTCTCCAATAATATGCTGTATCTCCCCACCCCACCCCCAAATCTGC TGTTGTTAACAGTATGGACATCTTGATTTTTTTCTTTTATATATCCATTTTAAAATATTC ATTATTCTTGTATGCTCTCTGCCTCTCTATTCTCCTTTCTCCTTCACTCTCCATTTATCT ATATTCTTATATATATATATATATATGTAGTTCTCTTTCCCCCTTAGCAATAAATGGAAT TATGTCTTCTACAGTGTTTTTCATAAGCCTTTTTTGGCTTCTCTGTAAATCTTGGTGTCA ATCAGTACCCTCTTTGTAATGGCTGTTTGGTATTCTGTTTCTTCTTTTTTTTTGGAAGTG CTACAAATTATTTCTTCAAATGGCCCCCCTCTATTTTTTTTCCTCCGAACTCCTGTTGAA AAATATATGAACTCTTTGCAAGTTTTTGCTCTGGCAGACAATAAATAACCTGCATCTTAA TTCTGAGCACTTTGAAGCTTTCTGACAGTTGCCCAATTGGTATTTTAGCCTCTTAGAATG TGGAACTCTATTGTTCAGACAGAGGCGTATTGAAAGCCTTGGTACACACAACAGATGCCA GTGGGGCTCCTCAGGTGGACATCCCAGTGGGAGGTTACTGCCCCTGAATTATCTACAGGA GCTCGAAGAGGCCCCAGAGCACGATATGGAGCTTTTTAAAGCCTTGAGAAGAAGAACCCT TGCAAGTGGACTGACTGGGGAGCTTCAAGCCTGAAGTCTGACTCATTTCATGGAGAAGCT AATTAGAGAGGACCCTTCCCGCCATCCTCACGGTGCAGTGCAGAACAGCATCCCTGGTTG GTCCCCACAGTGTGTGTATCACCCCTCAGCTTGGTGCTGTGCCTTACACATACAGGGAAC TGGGGTGGCTGCCCCTTAGAACAGCAGGAGTATTAAGAGTCCATGCAGTGTGTGGCCCTG TCCCTACTTCCATCTCCACCTTGTCCTACTCTGGTTAAATAGGGAGTACATTGTTTTGCC ATATTTCTGTTTTATACATTTCTAGGACTGAACATTTTACAGCAAACTTGTATTGCCTTT GTATGTTCAAGAAAAATTATTTTTAGAAATTTAAGCCTGGGCAACATAGTGAGACCCAGT CTGTACAAAATATGAATTAAAAAAAACTTAAAAAATCAGCAGGCATGATGGCGCACGCCT GTAGTCCCAGCCACTTGGCAGGCTGAAGTGGGAGGGTTGCTCGAGCCCAGGAGGTCGAGG CAGGAGTGAGCTATGACGGTACCACTGCAATCCAGCCTGGGCAGCAGAGCAAGGCCCTGT CTCAAAAAATAATAATAAAAATAGGCCAGGCACGGTGGCTCATGCCTGTAATCCTAGCAC TTTGGGAGGCAGAGGCAGGCAGATCACCTGAGGTCAGGGGTTCGAGACCTGCCTGGCCAA CATGGTGAAATGCCATCTCTACTAAAAAAAAAAATACAAAAATTAGCCAGGTATGCCAGA TCTGACCTGCAGACCCTGACCCAGTGACGGATAAAAGACTGACACGGATATTTTGCCTGT CAGCATGGCTAAGAGGCTCTGCTGCCTGACTACAGCATTGGCCTCCATAAGCCGGCAAAG TTCGCATTTATTTAGTACAGATTAAATGACAAAGGTCTCGAGTAAACACCACTAGAAGGT AATTAACATTGCCGACCTCCTGAGTAGAGAGCAGTCATACACCCACAGATGATCAAAGGT CGGTCTTAGGACCACATGAGTAAACAAGCTATTTAGATAAAACCCCCCACATTCACTTAC TATTTGCTCTTTTGCTATCAACTCAAGGTAAAGAGGATTAGGCTGCCTTCAGCCATAACC CTTTCCTAAAGCTTTTGTAAAACCTTCCGGCCTTCCAAGAAAGCTTGCGTTTTTCCTATA ATTTTCTCTTACAATTTCTGACATCACCCTAACCGAGCTCCTACAGGGGCATGGTAGCAG ACGCCTATAATCCCAGCTACTTGAGAGGGTGAGGCAGGTGAATTGCTTGAACCCAGGAGG CAGAGGTTGCAGTGAGCTGAAATTGTACCACTGCACTTCAACCTGGGTGACAGAGCAAGA CTCTGCCTCAAAAAAAAAATAATAATAATTATAATGATAATAATAATAGGCCGGGCACAG TGGCTCATGGCTATAATCCCAGCACTTTGGGAGGCAGAGGCGGGCAGATCACCTGAGTTC AGGAGTTCGAGATCAGCCTGACCAACATGGAGAAGCCCCGTCTCTACTAAATATACAAAA AATTAGCTGGGCATGGTGGCTCATGCCTATAATCCCAGCTACTCTGGAGGCTGAGGCAGG AGAATCACTTGAACCCAGGAGGTGGAGGTTGTGTTGAGCCAAGATCATGCCATTGCACTG GGCAACAAGAGCAAAGTCTCAATAATAATAAATTTCAATTAAAATTCCAAGACAGTAGCC TATCAGTAAGTGAAAAAATTGGTGTCCATCCTCATCCACCACTCCAATATTACACCTAAT AGTTTGGCATTTATCTTGCCTGACCTTTCTATGCATCTACATAAGTTTATATACTTTTTT TCCTTTGCAAAGATAGGCTCACACGTATACAGCTGTGTGACTTTTTGTCCTTTTTTTTTC TTTTTTTCCCCCGCCACCCTCCCCCCCGATTTTTTGTATGTAATATGTCATAGATGTCTT TATACCTCAAATATACCTCAAAACATATAGATCTGCCTTATGCTCTTTATTAGCTATATT ACTTGCTTGGTGCAACAGTGCAGTAATTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTAC ATTTTGGAACTTTAAGCTGTTTTCACTTTTTCTTCAAATGATCTTAGAGTTGATATAAAG ATATCTTCATCCAACAGGAATGATTGACCCAATCATTTATAGTAGCTAGGCAGCATGAAT AATCAAAACATACAGTTTACCTAGCATCTTCAGCTAAGCCCTTATTTTCAGCTTCTGTCT GCATCTCACCCTTTCCCGCAGCTATTTGCTTGTGACATATATTTTGGAGTCCATCTGTGG GGTTTTAATGGCTTTGTGTTCTGAGTGTTTGATTTCTTCCTGTCCTTGCGGAAGTTTCCC GAATACCGTGTTCTTTCAGTGGTCCACAGACCTTTTGAAACTACTCAGGTTGAGAACAGG AGAGCCTGAAACTTCAGATGGAAAATGTCAAATGTGATATTTTGCCAGTGAGCATCCCTG GCATTTACTCGTCATATATACAAAATAATGAGGTAGTCTGTCCCCATATTTTTAGCAAGG ACCCCAACAATTCTTACAATAGAGCAGTCCAAGAGTACTACAGTGCTCTTACAAATATGG GGGCAGTGGCTATGTTTATGCAATTTTTCTTACTATGAATACGGGGACGGTGGCTGCGTT TCTGGAGTTTCTCTTACTACGAATATGGGGATGGTGGCTGTCTGTGTTTGCTCTCTGCCC AGCAGAGAGCAGTGCCGTGAGATGCGTCAATTGCTGTGTGGAAAGAACCATAGAATGCTG CTCAAAAAAGTGAAGTCCCTTTTTCAAGAAAAAGGGGTCTCAAATACAGTGACTGTAGTG TTGGGTCAGCAAGACCTGAGTGGGGTTTTTCTGGTTTGGGTTTTGCCTTTAAGATGGGAT ATGCAGTGATTGTTCTGAGATACTGGAAATATAAGCAGAAAAAAAAAAAAGGTATATGGA AAAGAAACATGGATGTCCCAGCAGGGAACGGTGGCTCACGCCTGTAATCCCAGCACTTTG GGAAGCCAAGGCAACCGGATCACCTGAGGCCAGGAGTTAAGACCAGCTTGCCCAACATGG TGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCTGGCACGGTGGCATGTGCCTGTA GTCTTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGCTG CAGTGAGCTGAGATCACATCACCGCATTCCAGCCTGGGCAACAGAGCAAGAGTTCATCTA AAAAAAAAAAAAAACAAAAAAACATGAATGTCCCATGAACCCCAGAGGACTTGGATGAAG GAAGCCTAGTCCGTGTACTTGCTGCTTTTCCCCTTCCTCTAGTGGAACCAGGACAATATA TATTTTTTCCTTTTCTAAAAAAATTTTTGTGGGTACTTAGTAAGTGTATATATTTACAAG GTACATGAGATGTTTTGATTCAGGCAGGCAGTGTATAATAATTACATCCTAGAGAATGGT GTATCCATCCCCTCAAGCATTTATCCTGTGTGCTACAAACAATTCAGTTATATTCTTTCA GTTATTTTTAAATGTACAATTAAATTATTGACTAGAGTCACTGTGTTGTGCTATCAAATA CTAGGTCTTATTCATTCTTTCTATTTTTATTTTGTACGCAGTAACCATTCCCACTCCCCA CCATGCCCCACCATTACCCTTCCCAGCCTCTGGTAACTATCCTTCTACTCTCTGTCTCCA TGGGTTCAATTGTTTTTGTTTTTAGCTCCCACAAATAAGTGAGAACATGCAAAGTTTGCC TTCCTGTGCCTGGCTTAATTCACTTAACATAATGCCCTCCAGTTTCACCCATGTTGTTGC AAATGACAGAATCTCCTTTTTTATGGCTGCATAGTACTCCATTGTGTATATGTACCACAT TTTCTTTATCCGTTTGTCTGTTGACGGACACTTAGATTGCTTCCAAATCTTGGCTATTGT GAACAGTGCTAAAACAAACAGGAGTGCAGATATCTCTTCGATATACTGATTTCCTTTCTT TTGGGGGTAAATCCAGTGGTGGGATTGCTGGATCCTATGGTAGCTCTATTTTTAGCTTTT TCAGAAACCTCCGAATTGTTCTCCGTAGTAGTTGTACTAATTTAACATTTGCACCAGCAG TGTGTGAGGGTTCCCCTTTTCTCCACATTCTCACCAGCATTTGTCGTTGCCTGTCTTTTG GATAAAAGCCATTTTAACTGGGGTTCGATGATATCTCATTATAGTTTTCATTTGCATTTC TCTGATCAATGATGTTGAGCACCTTTTCATATGCTTGTTTGCCATTTGTATTTTTTTTTT TGAGAAACATCTATTGAAATCTTTTGCCCATTTTTAAAATCTGATTATTAGATTTTTTTT CCTATAGAGTTGTTTGAGCTCCTTATGTTCTGGTTATTAATCCTTTATCAGATGGGTAGT TTGCAAATATTTTCTCCCATTCTGTGGGTTCTCGTTTCACTTTGTTGATTGTTTCCTTTG CTGTGCGGAGCTTTTTAAGTTGATGTGATCCCATTTGTCCATTTTTGCTTTGGTTGCCTG TGCTTGTGGGGTATTACTCAAAGAGGGGACAATATTCTTTACTACTGGGAATCTGAGTTC TCCTTTTTCTGTAGGTCTTTAAAAAAAAATCCGTTATATCTTAAATGAGCTTCCATAGCT CTTAATAGCTACAAAACAAAGTGTTACATGAAGTTGACATGATTATTCTGAACTTTAAAC TATAAGGATAAACTGCTGTCACATGGGGTAGGATTTGATTTCTAATTACTTAAGATAAGA TTGAGAAGTCTCCAGACAATATTTTCTATATGGGGCAAGTCTTCTGAGGATAGAACTAAA AATCTGCTTTGGAACCCTGCATGCCCCAACCTTTAAATAACTGTTTATTTTAGCTCCGTC CTTTAGAGTGGAAACTGGGCGGGGTGGGTGAGAGGAGCCAAGTTCTGGGGACAAAGCTGC TCTCTTTTTAATGAGGCATAATAATAGGCACATTCTCTGGGCCAGTCAGTAACAAACACA TAAATAGAAAAAAATGGTCTTTCAAGTTGCTCTGAGCAGAATTTGCATTCCCACTGAGAA CCTTGTTTCATGATATACTTACTTCACTGTGGGACTGCCGGAGGACTAAGGAAATGAACT GCTTAAAGATAGGGCCTAGGAGATCCTGTGGGTTCCATAAGTAGGGCCATGTTTTTCTTT CTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTCCTTT CTTCCTTTCTTCCTTTCTTCCTTTCTTCCTTTCTTCCTTTCTTTCTTTCTTTCTTTTTTT TTGAGACAGAGCATTGCTCTGTTGCCCAGGCTCGGCTCACTGCAACCTCTGACCGACGGG TTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCATGTGCCACCA TGCCCAGCTAATTTTTGTATTTTTAGTACAGACAGGGTTTCACCATATTGGCCAGGCTGG TCTCAAACTCCTGACCTCAAGTGATCGACCCACTGGCCTCCCAAAGTGCTGAGATTACAG GCGTGAGCTACCGTACCTGGTTGGGCCATGTCTTACTAGTGGTCACAAGATAGAAGACCC TGCAGGCTCTGACCCTTTCTGGAAGGTTTCTCTATCAGAACGGACATCAGGTGGCTTTTC CTCAAGCCCCATATTTAATGTCTCTCCCCAAAACAATTGAGATAAGTGGATTCATAGACC AAAATACGTAACAGGCTTAGAAAATAAGTGTTGGCCCAATGCGGTGGCTCACGCCTGTAA TCCCAGAACTTTAGGAGGCCGAGTCAGGCAGATCGCTTGAGCTCAGGAGTTTGGGACCAG CTTGGGCAACACGGTGAAACCCCATCTCTACAAAAAATACAAAAATTAGCCAGGGATGAT GGTGCACTCCTGTAGTCCCAGTTACTGGGGAGGCTGAGGTAGGAGGATGGCTGGAGCCCA GGAGGCAGAGGCTGCAGTGAGTCGAGATCACACCGTTGCACTTCAGCCTGTGCGACAGAG CAAGACCCTGTCTGGAAAAAAAAAAAAAAAAACCAGAAAAAAAAATAGTTGTTAATTAGT ATGATTATGTTGGTCTCATTGCCACAGTTTATGTTGTCAACGCTTTCTCTCACTTTTTTT TCATCTGTTTGTCTACCTGCCCATGACAGTACCCTGTTCACAGTTGGGGCTTAATAAATG TGGAAGGGGTTTGAGTTTGGGGTTCAGGAGACAGCCAGGCAAAGAAGCTTCCAGAGCAGA GCTAACTTGACTCAGAAAGCTTTACAAGGAGTGTCTTTCTGTGACATGTTTTTTTTCCCT CTCCTTTGAAGAAGGAAGAGATGGCAAAACTCCACCATCCATCTTCAGACACATACTCTT CTCATTAAACATAGGCCTTTCTTCCCAGGAAAGTGAGCATTTGCTGTTGCATTTGCCCCT CTGGTGTGCTGGCCGGTGTTCCTGTTTTAATTCAGGATGCTGTTCACCCCTACAGTGTTC TCTTTGCATCACTGGAAGTCGTTTTGGAGTGGAAGTCCATTTGGACCATGAAAACATTTG ATCTTGTCGGGTAGTTTAAAATTTCATTTGTCAGGTCAGTGTTTTGATTGTTTTGACCTT GAGGCTTTTTCTCACGGTCAATACCTTGGCAGTTTTAGAAAGAACTTTCACTCCCTCTCC GTCTTCCCCTCCACCTCCCATCCTTCCTGCTCTCCCTCATCCCTTCCACCCCGTCTCCTG TTGTGCACACACATTCTCTCTCCACTCCTTTTCTTCCTCTCTTACTCCCTTTGAAGTCTT CTTGTTTTACAGATTTTTTCATAGCTCTTTAAATATCTTCATTTCCCAAACGATTCTATG GAGCTGATGTTAATCAGAAGCCTTTAAGCTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGT GCTGTGTTCCTTCAGACATTTTGATGGCTATTTAACAAAAATGGTGTGCACTAGAATAGA TTCAAACTGACCTGGGTTTGAGCTGCAGCTCTACTACCAACACTGGAACTTCATACACAG GACACTGTTGCAGGATGAATTGCTTCTCTTTCCTTCCCTTATTTCTCGTCTGTGAAGTAC ACGTGTTGACAGCACCTTCCTCGCACTGGTAGACATGAGAATTCAATGAACCAATCCAAG TTGAGCTTTAGCCCAGGCAACTGTCATTTCTAGACTTTTTACAAAAATTTGCGACCTGCT TTTTTCACTTAATAATCTAAAGACAATTTAACAGAGGTTCTCTGAGCTGAAGCAGTGCCC TGTCAAGCAAATATTCCTCCAGCTCCATCATGGTTTGCAGAAACCTTCTGCTAGGACCTG CCCTCGGCATGGCCTGGCTTCTACCTAACTCTCAGGACTGGCCTTCAGGCCACGTGAAGA AGAAAGCCAACTAAATTTCCCAGAGTTCTAATATACTGACTTTTATCTTCTGTCTTGCAG CTGATGCTTTTTTCAAAGCCGCTATAAGCCTTGTTCCGGAAGTTCCAAAGATGATTAATA TTGATGGGAAGATGCGGCCATCGGAATCGTTCCTTCTGGAATTCCTCTGCAATTTCTTTT CTACTTTATTAATAGTTCCGGTACGTTTCCTCAGCAGAACCGCAGGACATGTCTTCCTTT CACCTGCCTTATAATATTATATGTGTTCTTAGGCCTAAAACTGCAGGAACATTCTATCTA GTATCTTTGTGTTGGTTTTCCAGTTAGGTATTTGAATTGCTTAATGAATTTTCTATTCTT GCTGGGTGGGGATCATACTATAATAGTAGAGGTGAGGTACTATGTCAGCTCAGGCTGCTA TTACAAAGTGCCATAGACTGGGGTCTTAAACAACATTTATTTCTCAGAGTTCTTAAAGCT GGAAGTCTGAGATCAGGGTGCCAGTCTGGTTGAGTTCTAGTGAGGACCCACTTCCAGGTT GCAGACAACCATCTTCTCTCTCTTTCTGTCTCTCTTTTTTTTTTTTTTGAGATGGAGTTT CACTACTGTTGCCCAGGCTGTAGTGCAATGGCATGATCTTAGCTCACTTCAACCTCCACC CCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTAGGATTACAGGCGCCC GCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGTTC AGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAGAGTGCTG GGATTACAGGTGTGAGCCACCATGCCAGGCCTTTTTGTGTGTTTGTTTAGGAGTCTTGCT CTGTCACCCAGGCTGGAGTGCAGTGGTGCAGTTATAGCTCACTGTAGCCTTGAACTCCTA GGCTCAAGTGATTCTCCCGCCTCAGCCTCCTGAGCAGCTGGGACTGCAGGCCCATCTTCC CGTTATGTCCTCATGTGACAGAAAGAAAAAGCAAGGGCAAGCTCTCCGGCCTTTTGAGCA ATTGGTCCTCTGGGACCTAATTACTACCCAAGGGCCCCACCTCCAAATCCCATCACATTG GGATTAGGGTCTCCGTGTATGAATTTGCAGGGGGATACAAATATTTAGTCCACTGCACTC TCTATACTGCCAAGGCAGAGGTGTCGCCCAGTGGGGAAGGGCACAGGCCTCGGAACCAAG ATGTCCAGCATGGAATCCTGGCCCATCCTTCTTCCAGCTCTGCGTTCTTGGGCAATAATA TAACATCCCTGGGCTGCAGTTTCCTTGTCTATAAAATGAGGATAAGAACTGTCACTTCTG GGTTGCCATGAATATTAAGTTAGTGAGTACTCACAATGTCAGAACCATGCCTCTGCACAT AGTAAACTTTCTAGAAAGCACTAAGAAGGTGGCGACAAAGTTCTTTTGATGGCAAATAAC AGAAACTAAACATAGCAGAAATTAAGAGGGGCATTGTTGGAAGGATGCTGGGTTTTTCCT GGGATGGAAGAGATGTACAGCCAGGCTTGAGTTGGAAAGAATGAGGCCACTCCCGGGACC CAGCAGGAGGAATTCCTGGACCCTCCCTAGCAAGGGTCCTTATAACTTGGAGTCCATCTA CTCCCTGGGGGTCTGGCAGAGTGACATGAATTTGGATGAGGAAAATGACAGCTTTATTTT AACAAACCTCTGAGTGAAATTTACCTTTCACTCGATGAATTACAGGCAAAAAGCCACAGT AGTAGTAGCAGTAGCTGGGACTTTGTCACCAAAAGAAATCAACAGATATGTTCACATCAC ATTTCAGATGTGAAAGATATTTCAGAAGATTGTGTATGTTCTTCTTCCTTTCAAAGCACA GCAGTTATTAAGCCCATTGCTAGAGCTGTTAATGCATTCACAAAGAAGCAACAGATTACA GTATCACAGAAGCATTGAAAAAATATTTTGCCAGCTGTATTTTAGTGTAATTGGTTTGCT TTTTAGTCTTATGTGTTTTATTTGCTGCATTAAAAATAATATTCCAAGGACTGGGCACCG TGGCTCATGCCTGTATCCCAGCACTTTGGGAGGCGGAGGTGGACAGATCACCTGAGGTCA GGAGTTTGAGACCAGCCTGGCCAACATGGCACAACCCCGTATCTACTAAAAGTACAAAAA TTAGCTGGGCATGGTGGTGGGCACCTGCAATCCCAGCTACTTGGGAGGCTGAGGCAGGAG AATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCACCGCACTCCA GCCTGGACAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAATGTATTCCAAGGGCCA GGCATGATGGCTCACTCCAGTAATCCCAACACTTTGGGAGGCTGAAGCAGGTGGGTCACC TGAGGTCAGGTGTTCGAGACCAGCCTGGCCAACATGGTAAAACCCCGTCTCTACTAAAAA TACAAAAATTAGCCAGGAGTGGTGGCAGGCACCTGTAATCTCAGCTACCAGGGAGGCTGC GGCAGGAGAATCGCTTGAACCTGGGAGGTAGCGGTTGTAGTGAGCCAAGATTGTGCCACT GTACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAAAATAAAAATAGTATTCC ATGGAGTGTATAGGCTTCACCTGGCTGCCGCAGGGTGCATGGCACAGAACAGATTAAGCA CCGCTGGTAGAGCTTAATGTGCATGGGAATCTCAGACTCTTGTTAAAATGCAGATTCCTG GGGCCCCTCCCAGAGTCTCACTCAGTAGGTTGAAATAGGCTCACAAATCAGCATTTTTAA AATCATCTAATTGTTTTATTTTGAGAAGGGGTCTTGCTGTATGCCTAGGCTGAGCTCCTG GGCTAAAGTGATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGCCAACAGGCATGTGCCAG CCACCACGCCTGGCTAATTTTTTTTTAATGTTTTATAGAGGTACATTCTCACTACATTTC CCAGGCTGGTCTTGAACTCCTGGCCTCAAGCAATCCTCCTCCCTCACCCTCCCCAGTACC TGGGATTACAGGTGGGATCAACCATGTTTGGCAAATGGGCATTTTTAAAAGCCCCCTTCA GTGATTCAGGGGTAAGTGGTCCTAGGACCATATTTGAGAAACATCACCCTGAACTTGAGC CATAAAAGTGCCTGAGCTCCAGTGGATCCAGGTTCCTTTTTGGGGTGATGATATGTTCCA AAATTGACTGTATTGATGATCGCACAACTCTGTGAATATCCTGACAATCACTGAATTGTA CATTTTAGCAGGTATACTGTTTGGCATGTGAATTATATCTCAGTAAAGCTGAGAAAACAG AAAGTGACTCAGCTTCTGACTCTCCCTGTTCAGATTCCAAGTCTTCAGACAGAGGGGAGC GAGGTCAGGAGGCCAGGCTCAAGGACTGCAGACATGGCTTCAGGATGGGGGCCTCTTGTT GTCCTGCAGGGAGGATAGGCGGCACCCCAAGATGGGGCAGCGTGCACTGGCATTTTCTAG AGCCCCTTCACTTGACACTTGATGTCACTGTTTTCAGATCTCCATATTAGTACTCTGTAA GTTTCTCTCTTTGGGTAAGCTAGTTATTTATCAAGTGAGAAGGCAAAAGAAAAAAAATCA GGGTTTTGAATTAAGCAGTTGGTAAAAGTGAGAAGGCAAAAGAAAAAAATCAGGGTTTTG AATTAAGCAGTTGGTAAAAGTCATTGTTTATTGATTAATCGGGATGCATTCAGCATCTGC AGGTTAAAAATCACTGGAGCCTTTTTGAAAAGCCTTCTCAGATTCAGAAGCTTCTGTTCA GTCCTGACCTGAAGAGTTCATAGCGCTGAGACTTTGGGAAAGTTTTATAACTCCTCAGAG CTTCAGTTGTCACCTTTCTGAGGTGTCATCACAGTGCCCACCTCAAATGACTCCTGTGAG GGTTAAATGAAATGATAGCTGGGAAAGTGCTTTGTAAACCTGAAACTCTGTCCCTGGGAT TACAGATTGATGTCTGGAGGGCAGATCCAGCCGGTAGACATGTAGACACTTGCTGGCTAT GTCCTGATGGAGAACATTTGGAATGAGTTTCCTACATTTAAAAATTGGTAGATCACAGAA AATCCCAGATTTGCATCTCCCCTTGAAAAATCAGGTCCTATCACGTGGGGCCCGCATCCT GCGACCTGGCCAGTTGGCTGCAGCTGGGTACCAGCTGCCCTGTGCAGGCAGCGTATGCCT TTCTCTCCAGTTTTCCTGGGTACCTCTGGACCCATTAACCCCATTTCTGTTGTCCACTTG GCCCCTTAGGCATTTGTGGAAAGAGCTCCTGCTCTCAACAGATTCATTATTCCTTGAACA GATTTGAGTTATTTATTCCTTGAACAGATTTATTATTCCTTGAACAGATTTGCGTTATTA TTCCTTGAACAGATTTGAGTTATTTTTCCTTGTAGCATTGCATGTGTTTTAGCTGGGGTT TAGTAATGATATGAGACAAAGAATAGCTGCAGTTCACAACACCTCACTAGGTGCCCCATG CCTTGCTAACGCCACTCATTAATACTCACTTCCTGGGAGTCCTCCACCCAAGCCCCCCAA GGTAGGAATCATTGCACCTTTTTCACTCATGAAACCTGAGCCAGAGGGCCCTTGCAATGT GCCTGAGGTCACAAAGCTTATAAGTAGCAGAGCTGGGATTTGAACCGAGGGCTACGCTAT TCCAGAGCCTGTCCTGCATGACTGAAGCCGGAAACGTTTGCAGTGTGCCTTATTTGCTCA AGTTCATTGAGCACTAGCAACCCTGTATCCCTCCTTGTGGGACGCGGCATTAGTAACTAC TCACAGATGCTACAGGATGTTTATCCTGAATAGCCAGGGCTAAGAGCTGAATAAACTCTC AGGTGATGGGATGCGCCACACCTGAGCCATGCCCATTATGAGTAGATCTAGCATTAACAA GACTCCCACATCTCACTTCTACCTGGTTCAGTTTTTTTCTTTTTCTTTTTTTTTTTTTTT TTTTTTTTTTGGAGAATCTTCCTCTGTCACCCAGGCTAGATGGAATGCAGTGCGCGATCT CGGCTCACTGCAACCTCTGCCTCCTGGGTTAAAGCAATTCTCGTGCCTCAGTCTCCCAAG TAGCTGAGACTACAGGCGCCCACCACCACACCTGGCTAATTTTTTTTTTGTCTTTTAGTA GAGACAGGATTTCATCATGTTGGCCAGGCTGGTCTCGAACTCCTGAGCTCAAGTGATCTG CCTGCCTTGGCCTCCCAAAGTGCTGGGATTTGTGCTGGGATTACAGACATGAGCCTCTGC GTGCAGCCTACTCAGTTCAAATTATTTGTTACCTTTCAGGTCACAGCTTTTATTTTAGTT TTATTGTATTGGGGCGAGAACACTTAAGGTGAGATCTACCCTCTTAACCGGTTTTTACGT GTACAATACATTACTATTGACATAGAAACTGTGCTGTGTAGCAGATCTCTAGAGCTTATT CATAACTGAAACTGTCCATTGGTTAGTAATTCTTCATTCCCCTACCCCCACCCCCTGCAA CCACCATTCTACTCTCTGATTCTATGAATCTATTTTAGATACTTTCTTTATATGTGGACT CATGCAATATTTGTCTTCCTGCAACTGGCTTATTTCACATAGTTTAATGCTTTCGAGGGT CATCCATGTTGTTACATATGGCAGAATTTCCTTCTTTTTTAAGGCTGAATAATATTCCAT TGTGCATGTGTATAATGTTTTCTTTTCTTTTCTTTCTTTTTTTTTTTTTGAGACAGGATC TCACTCTGTTATCCCGGCTGGAGTGCAGTGGCATAATCACACTAGCGGCATCAACCTTGA CCTCCTGGGCTCAAATATTGTCCCAACTCAGCCTCTTTGAATAGTTGGGACCACATGGGC AAGCCACCAGGCCCATCTAATTTTTGAGTTTTGTGGCGACAAGGTCTCACTATTTTTCCC AGGCTGGTCTTGAACGCCAAGGCTCAAGTGCTCCTCCAGCCTTGACTTCCCAAAGTGCTG GTGTTACAGGTGTGAGTCACTGCACCCAGTCTTTTTTTTTTTTTTTTGAGTCTTGCTCTG TTGCCCATTCTGGAGTGCAGTAGTACAATCATAGCTCACTGCAGCGTGAGCCACTGCACC CAGCTACCTCATTTTTTGTTAGCAATTTATCTGTCAATGGACATATAGATTGTTTCCACA TCTGAGCTCTTGTGAATAATGCTGCAATGAGCATGGGAGTGTAGGTATCTCCTCAAGATC CTGATTTCAATTTGTTTGGATATGTACCCAGAAGTAGCATTGCTGGGTCATGTGGTAGCT CTATTTTTAATTTTTTTAGGAAACTCCATACTGTTTTTGTTTTGTTTTGTTTTGTTTTTG AGACAGGTCACCCAGGCTGGAGTGCAGTATTGCAGTCTCGGCTCACTGTAACCTCTGCCT CTCCAGTTCAAGTGATTTTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCGTGTG CCACCATGCCCAGCTAATTTTTGTTTTTTTAGTAGAGACAATGTTTCACCATGTTGGCCA GGCTGGTCTCAAACTCCTGACCTCAGGTGCTCAGCCCCCCTCCGCCTCCCAAAGTGCTGA GATTACAGGCATGAGCCACTGCACCCGGTCCCCATACTGTTTTTCATGGGGACTGCACTG TTTTGCTTTCCTACCCACAGTATGAAAGATTTTCTTAAAGGATGGGTTTGAAAGTTTGAT TCATTTTATTTGTTTAGAAAAGATAGGAACTACCAGGCACGGCTGCTCATACCTGTAATC CCAGCACTTTAGGAGGCCATGGTGGGTGGATCACCTGAAGTCAGGAGTTCGAGACCAGCC TGGCAAATGTAGCAAAACCCCATTTCTACTAAAAATACAAAAGTCAGCTGTGCATGGTGG CATGCGCCCATAACCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAATCATTTGAACCCAGG AGATGGAGGTTGTAGTGAGCCAAGATTATGCCATTGCACTCCAGCCTGGGTGACAAGAGC AAAACTCCGACTCAAAAAACACACACACAAAAAGAAAGGATAGAAACCATTTGATACCAG ATCAAGTCCCTGGTCCAATTTATTGATTCTTACAAATGTGGGAGTAAACAGTCCCCAGGG TGGCCCTCTCTCCCCTGCAGACAGAGAACTTTTTGGAGCATGTTGAAATGTTCTGCTTTA GCATCAGTAGTCGTCAGCCTAGTCAGGGACTAGTTTGTGGAATAATCTTCCCTATATAAT CAAACTGGCTCATTTCATGTAACAATGTGGTAAGACAAAGTAGACTTGACTGAACAAGTT CAGTGTCACAGTTTTGAGGCCTAGTTTTGATACAGTTGCAATTTGCAAGAAATGGAAATG CTACTACCATCAGTTTTGTAGCACTAACGATCTCGGATCCAGCAGGGAGATGTCTTTTCT CCTACTTATCCTGGAGAAAAAGGTCCAGCCATAAACACAGCAAGTTGTCCAGGTCTATGT TTCATCATTCCGTCTATTCCACAAACATTTGTCGATCCAGGAATTAAGGAGTGAGCAAGA GAAGCATACCCCAACTCAGGAGGACAGACTTCATGTTAAACAAATAAGTACACATTTAAC TACAATTGCACAAAGCGCCATAAAGAACTACAGAAGCCAACTACAGTTGGCACTGGTCCA CCAAGAGGCTGATGACTACTGATTAGTGCTGGAAAACTGATGGTATTAGTAATAACACTT CCAGCTTCTCAGGAGGCTGAGGCGGAAGGATTGCTTGAGGCCAGGAGTTCGAGACCAGCC TGGGCAACATAGCAAGACCTCATCTCAAAAGAAAAAGTTTTCTTTTTTTCTTTTTTTTTT TTTTGAGATGGAGTCATGCTCTGTCACCCAGGCTAGAATGCAGCGGTGTGATCTCGGTTC ACTGTAACCTCCGCCTGCTAGGTTCAAGCGATTCTCTTGCCTCCGCCTCCCGAGCAGCTG GGATTATAGGCACCTGCCACCGTGCCTGGCTAATTTTATTTATTTATTTATTTATTTGTA TTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGATCTTGAACTCCTGACCTCG TGATCCACCTGCCTCGGCCTCCCAGAGTGCTGGAATTACAGGCGTGAGCCATGCGTCCAG CAAGAAAAAGTTTTTTAATGAACCATAGAGACCTCTCAGAGCTCCAGATTTGGGGGATGG GGTCAGATAATCAGGAGAGTTCCCGAAGAAAGTGCCATTTGAGCTGTGATCTGAAGGAAC ACTAGTAAGTAGTCAGCTAGGCACAGATGGGGAGAGGAGAGGGCATTCTGGGCCGAGGAC ACAGCGTGGGTGAAATCCTGGAGGTGGGAAGCGGCACTGTGCTCCAGAGGGACTGGAGGA GAGCCAGAGTGACTGGCACATCAGGAGGGCACAGGGGATGCCCGAGCTGCTGGTGAGACA GACAGGACTGAGAGAAACAGCAAGCTGGTCTCTGACAGCTTCCCGTCAAGTGGTGATCTG TCTCCCTTCGTCCTCCCCTGCCCTCCCACTATCTCTGTTTTCCCCAGTGCCCTTTCTTTC CTTTCCCTGTTCTTCCTTTTGGAAGAACATACGAGCTCACCTGTGTTCTGGTTCCTTTTC TAAAGGGCTTTATGATTACTTAACCAACCTCATAACCATGGACCAGCCAACATTTCACAA ATACTCACTCAAAACAAGCCTGTTATTATCACCCTCGTTTCACAGAAGTGGAAACTGGGG TGCAGAAAGATGAAGGGTCAGCAGCTGGTCAGTGACGAGCCAGGGTCCAAGGCCAGGATG TCTGCCCAGCCGCCATGCTCACTGCCTTTCATCTTGGTTCTCCTAGGAAGAGTTAGTTAC TTCTAGGGTATTATTAGATTGGTGCAAAAGTAATTGTGGGTTTTGCCATTGAAAATAATT ACTTCTACACCAACCTAATACTTTTTTCCCAAGGGGTTTAGTAGAAGGATTCCTGCAGAC CAGAAACCCAGAGGGATATTGCTGATGTGGTAGGTGTTGGGCCAGCAGGGAGAGAGGTCT GAGCCCCTGCCAGGTGCTACCTGGGAGCCACTTTGTCAGCATTTGTTTGTTCTACTTGGG AGGTAGCCCTGCCAGGGACACCTGGGGACACCTTTTCCCACTGGAAGCGCCATCTGAATC CAGAACCGTTTTCTTTGTCTTAAGAAAAAAAAAAAATCTTTGTCTGCCTTACTTCAGCTG TTGGCACTGAACCATCTGTACATTTTTTTTTTTTTTTGAGAGGAGTCTCGCTCTGTTGCC CAGGCTGGAGCGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAG CAGTTCTCCTGCCTCAGCCTCCCAAGTATCTGGGACTACAGGCACGTGCCACCATGCCCA GCTAATTTTTGTATTTTTAGTATAGATGGGGTTTCACCATGTTGGCCAGGCTGGTTTCAA ACTCCTGACCTCAAGCAGTCCACCTGCCTCGGCCTCCCAAGGTGCTGAGATTACAGGCTT GAGCCACCACACCCAGCCCATCAGTACAATTAAAAAAAAAAAAGTTACAACCACTGAAGC ATGGATGTCACATGGGAAACTTTGTCCATGTACAGAAGGTTGGAAATAGTCTCCCAGCTC TTCGGTTGTGAGCAAAAGCTCACGGAAATGGCTCACTACAAACCTTTACGTCTCCACTGG CCCTTGTACCACCTTTTTGACAGTGTGTTGCATGGTCTGTCACAAGACTTATGCATTTGT GTTGAAATGAAGTTGCTGGAACATTCAGATTGTTGTCTATTCCCAAGGCAGATCCTTAAA TAAAATATATTTTTGGACAGCCACATAGCAGAACCGAATAGCCTAGTTAAAAACAGCTGT TAGCAAAAGAAGGCTGGGGGGGCGGGGGTGGGGAGGCGGGGGGGCGGGGAGGTTCCCAGC TGAAACCAGCTCTGAGTGGAAAGCAGATCATGGCATGGGCAATTTTGATGTGTGTAGTTT GTGGATGTCAGACTTTTGAGCATCTTGTATTCTCATTCTTGCCAGTATCATAAGAGCAAT TCTTTTTTTCTTTTTGTAAGATGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGC CATCATAGCTTTCTGTAGCTGAGACCACAGGTGCACACCACCACACGTGGCTAATTTTTT TTTTTTTTTGTAGAAACAATATTTGTTATGTTGCCCAGGTTAAGAACAATTATTTATTTA TTTATTTATTTATTTATTTATTTATTTATTTATTTATTTTTTTGGAGACAGAGTCTCGCA CTGTCACCCGGGCTGCAGTGCAGTAGTGTGATCTCTGCTCGCTCATCCTCCACCTCCTGG GTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACACCACC ACACCCGGCTAATTTTTGCATTTTTAGTAGAAACGGGGTTTCGCCATGTTGGCCAGGCTG GTCTCAAACTCCTGACCTCAAGGGATCCGCCCATCTCGGCCTTCTGAAGTGCTGGGATTA CAGGCGTGAGCCACCGCTATCTAGCCCAGGCTAAGAGCAATTCTTACAGATATTAACAGC TTGTACAAAACATCCCACGCCCCTCCACAATTGTCCTCACCCACTTGAAAGTATGACTGC AATATGTACACACATTCACGTTGGATATAATGGCAATGCTGCTCATACTCCACACTTGTA TTCTAAGTAGCTGACTGCATGTATGCCTCCCCCTGTTCACAAGTTCTATAAAGTCAGAGA CGCTTGGTTTATCTGCAGAGAGGCAGTGCGAATCTGGTACCAGTAGTTAGAAATGTCCAC TCTGGAGCCAAACTCCTGGGGCTTGAACCTTGGGTCCCCCATGTACCAACTGTGTGACCT TGGGCCACTTACCCTCTCAGTGGCTCATTTCCCATCTGCGAAATGGGGCTTCGTCGTAGT ATCACCCTGGAACATAGAAAAGCTATGGTAGCTGCTATTAATATTAGCTGTTGTTGTTTT CATAGCCACTTCAGTACCTGACACATAGAAGGTACCCAAAAACTACAATCCATTCAACAT TATTCACCCAATGCATGTCAGTGCCCAGCACTGTCCCAGGAGCCAGAGACAGGGCGGGAT TGAATGTCATCAGGGACACCATCCACATTGAGTTCCTGGAGGCGCCATTAACAGAATACA GTGTGCAGCCAGCAGACCTGGCGGTGTATTGGCAAATGCAATAGATGAAGTGCCTGTCCT CCTGGAGGTTATAGGCTAGCATGAAACAGAGAGAACCAGGAAAACCACGAGATATTGTTG GGCAGGTCATTGAAGGAATACCTAAGATCATTTCAGATAGTGAGAAGTGCTCTGTAAAAA ACAACACAGAGGCTGGGCGCGGTGGCTCATGCCTTTAATCCCAGCAGTTCAGGAGGCCAA GGCAGGTGGATCGCTTGAGCCCAGGACCTTGAGACCAGCCTGGGCAACATGGCAAGACCT CATCTCTACAAAAAATAGAAATTCGCCAAGCGTGGTGGTATGTACCTGTAGTCCCAGCAC CTCAGGAGGCTGAGGTGGAAGATCGCTTGAGCTCAGAGTCAAGGCTCCAGCGAGCTGTGA TTGTGCCACTGTACTGTAGCCAGAGTGACAGAGTGAGACCCTGTCTCAGAACCCGCCCCC CCCCTAAAAAAACAGGATGATTTGTGATGAAGAGAGAGTAAGAGGACTGCAGATGGAATG TCAGGGAAGGCCTCATTAAAGAGCTAATGTGTAAGATGAGAACTGCAGGCTACCAAGGAG CCGTCTGGCCAAGCCCTGGGGCACAGACTCTAGTCAGAGAGAACGTGCCTGGCTGGAGGC CAGCACCTGGACGTGTGTGCCAGCCCCTGGTGCCACTCTGTGCCCTTTGTCCTACTGTGT GTGGGGGAGACTGGCCTCTGGGGACTGCCTCACCTATCCTTCCTCTAGCTCCCAATTTGT TCAGCCAGTAGGAGGCAGCAGCATATGCAGGGCAGGAGGAAAGCGAGGCTGGGGTATTTC TCCCCCATTCCTCCTGGGCCATGTTTTGGCGATGGCTTTGTTCCTGCAAGCAAGACTACA TCTTGGGCTAGATGGCCTCTTGCCGCTGCAGGTTCCAATCATGCTGTTCCCCCTGCCGCT GCGGGTTCCAATCGTGCTGTTCTCCCCACCTTAATGTGGCTGGGGTAAGGGAAGGGGACC CGCATGGGGTGGGCTAGCAAGGCCATGGAAGGGGCTGGCCGTGCAGAGCTTCTGCACAGA GTGAGAAGTCTGGAGAGCTTTCAGCAGGGCATCCCCAGACTCACATACACCTTTTTGGAA TGGAATTGAAGCTGCTTACTTTTTTACACCCCAAAACTTTTTATAGATTCAGTTTAGCAT CTGAGAAACACTGTTTGCTATAAACTCTGTGACTGTCTCTCAGGTTTTGCCTCTCCCAAG AGAGCGTCCTCCATTTGGCTGTTACCGTTGTTGAGCATCCCAAAGAGTGAGGCTCTATTT AAAGTCACTGCCTCGAGTGGTGGCAGGGATCATCCGGGGGCTCACCCAGCGTAGGTGGCT TCTACCGTTCCATCTGCTACGATACCCGCGATCCTGCTTTTGTGGTTGGAACAGGGCTTC CTTTTTTTTTAACTCCCACCACCCACAGAAAAATAAGAGTGTAATTTTGGAAACAGGCCA TTAAGCTGACAGGTAACTTTGCCTTCTCCTTTTTGGGATCCAAAAAGGGATTCTCAAAGC TCGTTTGCCCAGACAGGAGCGTGTTGATTCGTGGGAATCACGTTTTGTCATTTTCCTCTG TATTGTTTAACCAGGCTTGTGAGTGGGTCTTGCCTTTGTTCAGTAACTGACAACGTTAAT TTCTCTACAGCTGCTGCGGGAGGATCTGGGCTTCTGTGTTGATTTTCTTTTTCCCTCCCT GCTTCATCTTTGGGATTATTTATCCTTTTTTCGGTTCTCTGCTAGGATCATCCTGAACAT GGGGTCCTGTTTCTTGTTCGAGAGCTTCTCAACGTGATCCAGGACTACACCTGGGAGGAC AACAGCGATGAGAAAATCCGCATCTACACCTGCGTCCTGCATCTCCTCTCCGCCATGAGC CAGGAGACGTACCTTTACCACATAGACAAAGGTAGCAGAGCCTCCCCCACCAAACCATGC TCCGCATGGATTTCATGAAAGGCAGACAGAATGCTTTCATTTTCTCTTTTATTTTTTCCT CCCTTGTATTTTAGCTTCCATGAACTTCTAGTCCAGGGTCTCACTGTATTTACCTGATCT AAGATTTACCTGGAGCAACTCTTAAGAGTACAGATTCTTGGGCCGGGTGCAGTGGCCCAC GCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAAGAGTTC CAGACCAGCCTGGCCAACAGAGCCAAACCCTGTCTCTACTAAAAAAACAAAAATTAGCCA GGCCTGATGGTGCACCCCTGTAATCCCAACTACTCGGGAGACTGAGGCAGGAGAATCGCT TGAACCTGGGAGGCAGAGGTTACAGTAAGCCAAGATGGCACCACTGTACTCCAGCCTGGG CAACAAGAGTGAAAACACCATCCCAAAAAGGAAAAAAAAGAGTACAGATTCTTCAGCCCC ATCCTGCCCTTGATTGATTGATTGATTGATTGATTGATTGATTGAGACAAGGTCTCACTC TGTCCCCCAGGCTGGAGTGCAGTGATGTGATCTCGGCCCACTGCAGCCTTTACAGCCCAG GCTGAAGCAGTCCTCCCACCTCAGCTTCCCAAGTAGCTGGGAATACAGGCATGTGCCACT GCTCCTGGATAATTTTTTAAATTTTTTTTTGAAGACGGGGTTTCACCATGTTACGCTGGT CTCAAACGCCTGGGCTCAAGTAATCTACCCGTCTCAGCCTCCCAAAGTGTTGGGATTATA ACCATGAGCCACCACACCTGGCCTTCCCTTCTTAATTTGCATCTTTAACAAGCACCTGAG ATCATGTTGAACATCAGACCAGTCTGGAGAAACACTGTTTAAAAAAATAATTATAATAAT TTCAACTTCTATTTTAGATTTAGGAGGTATACGTGCAGGTTTGTGACAGGGGTATATTGT GCAATGCTGAGGTTTGGGGTGCAAATGAGATAGTACCCAATAGGTAGTTTTTCAGCCCTT GTCCCCTCCCCTTCCTCCCCACTCTAGTGGTCTCCAATGTCTGTTGTTTCCATCTTTATG CCCATGGGTACCCAATGCTTGGGGCCCACTTACAAGTGAGAACATGGCGGTAGTTAGTTT TCTGTTTCTGCACTAGTTCACTTAGGATAATGGCCTCCAGTTGCACCCATGTTGCCACAA AGGCCATGATTTCATTCTTTTTTAGGGCTGCATAGTATTCCATTGTGTGTATGTACCACA TTTTCTTTATCCAATCCACTGTTGATGAGCATCTAAGTTGATGCTATGTTTTTGCTATTG CGAATAGTGCTGCAGTGAACATACGTGTGCATGTGTCCTTTCAGTAGAACGATTTATTTT CCTTTGGGTATATACCCAGTAATGGGATTGCTGGGTCAAATGGTAGTTCTGTTTTCAATT CTTTGAGAAATCTCCAAAACTGCTTTCCACAGTGGCTGAACTAATTTGCATTTCCACTGA CAGAGTGTTAAGTGTTCTCTTTTCAGAGGAACCCTCTTTTGGATCAGTGTGCTACACAAT AAACTGGAACAATGGCTAAATATACACATGCATGAGCTTCGTGCCAGGCCTGTTCCTTAC CACAGTCTCAGGAAGGACCCTGGTGTGGGTGTTTGCAACTGCTCCTCAGATGATGCCAAG GCTCAGCAGCCCTTGTCTGGGTGCTCTGGAGGAAGGAGGTGGCCTTGATCACCTGCTACC AGACATTTTGAACTTGCTAGTACAAGTTGGGAGCAGCCTCCTCGTGTCCTGGACTTACCA CAGGACATCCCAGTTCCAGGCCTTTTCCCACTGAGCCCAAGTATCCTCCTGCCTGGCGGA CCCTCAGTTCTAATTTTTGGATTCCAAAAATTGGTCTTAATGTCAAAAGTGCTTTGGCCA GTAATTGTATACTTTACAGTTAAAAAACCAACTCTACACTTGCAAGTTGCAGTGAACACA TTAGCAGTGCTTAAGGGATGGCCTGCCTTCTGTCATACCTCTCAGGCTTTCTCTAGCTGG GTCTGGGGACTGAGGATAAAGATGTAATGCAGGGAGGCTGGTTCATAGCAAGAATGATGG CGCCTACCCTGATCTGAGCACTTACTGCGTGCCAAGGACTACATCAGGCTCTACAGGCCT TTTTCCCTTAATCCTTACAGCTTTACTATGAGGACAGGCATTCATGTCCCCATTTGATGT GTAAGCAAGAGGAGATCCAGAAAGACAATGTGATATACTCCAGGGCTTCCGGTAGTTAGT GATGGAAGTGAAACTCACACCCAGAGTGGTGGGACGTGCATTACACTGCTTTGTTGATTA CAAAATAACAGTGTTGGCTGGGCACAGTGGCTTGTGCCTATAATCCCAGCACTTTGGGGG GCAGACGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGGCTAGCCTGACCAACATGGCGA AACCTCATGTATACTAAAAATACAAAAAAATTAGCCAGGCTGTTGGCAAGCGCCTATAAT CCCAGCTACTTGGATGGCTGATGCAGGCGAATCGCTTGAGCTCAGGAGGCTGCAGTGAGC CAAGATCACACCACTGAACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAA AAAAAAAGCAATGTTTTAATTAAAGTGTATTATATAACATATATGCAATAAACTATAGAG CTCAGTGAATTGTCACAAAGTGAACACTCGCAGGTAACCACAGTCCAGATCAAGAAATAG AACACCTCCTTCAGTCAGCATCACCACCCTACTCTCGAAGACACACCACTCTCTCTCCTG ACTTCTAGCATTATTTATTAGTTTGCCACTTTCTGAATAAGTAAATATTTGCAAGCATTC TTTGGTATTTGGCTGCTTTAACTCAGCATGATGTCCAAGATTCATCTGTGTTGGTATGCA AAACGGTAGTTCACCTTTTGCATTGCTGTATAGTATTCCTTTGTGTGGATGTACCAAAAT TGATTCATTCCTTCTGGATGGAAATTTGCATGTGGCCAGGTCCAGTTTGGGGCTATTATG AGTAATGCAGCTGTGAACATTCTTGCATGTATTTCTTGGTGTACATTCCCATTGGCTGTC TGCGTGGAGGTGGCGTTGCTGGCTCATAGGATCTGCTTATATTCTGCGTTGGAGGATACT GCCTCACAGTTTCCCAAAGGGTTAAACCAATTGACATTCCCACCAGGCACGAATGAGGCT TCCATTTGTTCAGTTGCTATGGTCATTCTTTTTCATGTCAGCTGTTCTAGGAGTGGAGTT TGCATTTCTCTGATGGCTGGCGAGGTTGAACACCCTTTCCTGTATTTCTTGGCGTCTTTG TTTCCCCTTTTGTGAAGTGAACATTGAAGGCTCTGAACAAGAGAGAAAGCTTTGAGGACC AGACAGAGACCTGGAAGTGAGGCTATCACAGGAGCATGCCCTGCCCTCTCCTCTCTCTCC TCTCCTTCCTCTCCCTCCTCTCCTTCCTCTCCCTTAAACAGATTCAGCCCATCCTTTCTC TGAACAAGGCCGCCAGCGAAGACGACTAGAGCCAGATTGGCAGCAGAGGGAGCGAGGCTA TATTTGATAGGCAAGAGTGTAGTTTTCTAGCTTTTAGAGATGAAAACAGAAGGATGGATT TTCTTTTTCTTCTTCTTAGTCCAGCTGTGTTTACTTTGAATGTGCAACTGTGACCTGCCC GGCGTCTTGGTAGGAGACCCAGGGAATCACAGAGTCTCTGCAGGTTGTGGGGGCTCCTTT TTCCCTGTTCACTTCCTCATTCTAGGGAGGCTTTTAGACGATGTTGACACAGCTTAGAAC TTGGAAGAGAGGGATTAAATAATTTCTGCATTTTTGGAGGATGCCTTGGCCACTTTCTTC CCAGATTAAGAAAAAGAGAAGGCTCTGACATTGCCTGGAGCAATCCCTCCGGTGCTTTTA CACGAGGTTACAAGACAGCGTGCATGTTTGATGTAGAAGTGAAGAATAGTCTTGGATCCT CAATGTTTATGTATTTAGTATGCAGATAGAGTGTGTCTTTATTGGAAGAGTACAACTCAG GATGCTTCTGTGAAGCCAAGGCAGCCCTCCTCACTCTTCCACGTCACCTGCCAGGCCCTC AAAGCATTCGGGTTTGCAACTTGGGGTGGGACAGATGCAGAGATTGTGGGCTATTTTTAG TGGCCATTTGCAGGGGACATCATTTCTCCCCCTCGTGAGAGCCACGTCTGGACTTGAAGG CCCCCAATACACTCTGACCTGACCAAATTACTTTTAATTCTCAAATGCGCCCTTTTCTCC TTCCCTCTATGACCACCAAGTGTCAGCATGGAAAATAAATTCCTCCCTTCTCACCCCTTT TCCCACTTCTGCTAGCGAATTCCACCTTTAGGACTCAGTCCAGGTCTCACTGATTCCAGA ATCCTGTCCCAAGCATAGATTTTAGTATCCCATGATCCCCTGTACTGCCCCCCCTTCCTT GAGACTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGAACTCCAGCCTGGGC GACAGAGCAAGACTCCATCTCAAATACCTCTGCACACTATTGCAATTGCCTGTTTGTGTG TCTGTGTCTCCTCACAGACTGTGACCTCTGTGTCTGTGAGGGTAGGGCCAGGTCAGCCTT GTCCCCCACTAGGTTCCCGCTCCTAGCCTAGAAGCTGGCATGAAGCAGGCCTTATTCAGT AGGTGTTGCATGTGTGTGTGAGTGGCCTGCTCTAAACACACCTCTGGCCCCTTGGGGTGG TTGGACCTTCCCTCTTCTCCATTGCTGGGCTGTTCAGAATCAAAGTGAACTCCAACCTGG AGGAAGACTGGGAATTTATGCAGGAACTATTCTGGTCCTCAGCAGCAGACATGAGAAATT CCTTCACCAGCTGCAGTTTTGCTGCCCTGCACAATCAGGTGGTGTTGAATGGCTGAATTG AATTCTTCTCGCTTCTTACAAGAGTAACTGCCGTCCCCCACTGGGGAGGTACAAGTCATG ACACAGCAGCCAGAGCCGGCTTGGAAATTCTGAGATTGACTCCTGCGGCCCAGGGCCAGT AACTACCAACCTGGTGTCAGACGAGCAATCAATCGCAAAGGAAACCTTGGGGAAGTATCC CAGCAGAGTCCCCATAAACGAGCAGTTTAAGATTGGATAAGAGATTCCTGTGATCAGAGA AGCTGGGGAACAAAGGAAACCAGTTGTTCTCCTTATTCTTAGGCAATATGCCTGCAACCT GCTTTCAAATGGTTCAGCCAAAAAAAAAAAATTATGTGTGTCTGTCCATCCTTGTAGAGA CAACAAGCAAGAGAGCTTGCACAAAAGTAGCAAAATATTATCAATTGGTGATTCAAGAAG TAGGTGTTCATGGCCGGGCGCGGTGGCTCATGCCTGTAATTCCAGCACTTTGGGAGGCCA AGGCGGGAGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGAGAAACC TCATCTCTACAAAAATACAAAATGTAGCCCTGCCTGCAGTGCAGTGGCGTGATCTCTGCT TGCTGCAACATCTGCCTCCTGGGCTCAAGTCATCCTCCCACCTCAGCCTCCCGAGTAGCT GGGATTACAGGCACACATCACCACATAGAGCTAATTTTTGTATTTTTATTAGAGACAGGG TTTCACCATGTTGCCTAGGCTGGTCTCAAACTCCTGAGCTCAAGTGACCTACCTGCCTTG GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCCATCTCGTGCTGTT TGTCCCTCGTTTGTGCACAGGCCCTACTGTGTTTCTCATAAATATTGTCTCTTTTGAATT GTGTGTATCTGAGACAGTATCCTTCCTACTTGTTTCCTCAAGACAGTGATGAATGTTCTT TCAATGGGGCGAGAAAAGCACAACAAATCACATTCTAGCAGATAAGCTAAACTGGATGTG GTTTATTAAAGACATCCCTAAGCCACAAAACTGGATTAGCCGTGTGCACTTGTGGCCGCG TGTACACAACCACACCCCGAGGCACAGGCATGGCTCTTGGTTTATGAGATATCCACGCAC TCAGGACAGTGACCCAGATTGCAGGCCCGTGCCAGGTGAGAAGCAGCGAGTGCCGCCGCC GCACCGTCCCCCTTCCTGACCACTGAGTGCTGTGTTGGCTCCAGAGCTCTCCCTTTAGCC TGGGGGTTCAGATGCTGAACTGGGCTCCCCAGACAGAGTGCTGCTTGTTCACAGCCGGTT ATGCTCGGCCACATACAAGTCCCCATCTGGTAGCTGGAATGAAAGCAGCTGTAAGAGGAT CCCATGGAAAAGGTATGTGAGCTCATGTGGGTGTGGAAGGAAAGAACTGGCTCTGTAGGC AGAGCTGGTGGTTTTGTTGTGAACTCTAGGGTTTGCAGCAGGCTGGCCCTAGCCAAAAAA GGAAGGAAGAAAACCACTGAAGTGTTCCCAGTAGGGACCAACTAAATACATTCTCTTCCA TCGTACAGTGGGATACTACGCAGACATGACAACAAAGCAACAGAGCTGTACGCGTAGCGC CCCCTTACCCGGTGTCTCTTCTTTTTTTTTTTTTTTTTGAGATGGAGTCCCACTCTGTCG CCAGGCTGGAGTGCAGGAGCGTGCCAGTAGCTGGGACTACAGGCGCGTGCCACCACGCCC AGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGACCAGGATGGTCTTG ATCTCTTGACCTCATGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTG AGCCACTGTGCCTGGCGTTTTTTTTTTTTGAGACAGAGTCTCGCTCAGTCACCCAGGCTG GAGTGCAGTGGCTCCATCTCGGCTCACTGCAACTTCTGCCTCCTGCGTTCAAGCGATTCT CCTGCCTTAGCCTCCCAAGTAGCCGGGACTACAAGCGTGCACCACCATGCCCAGCTGATT TTTTGTATTTTTGGTAGAAACTGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCT GACCTCAAGTGATCCACCCACCTCAGCCTCTCACAATGCTCAGATTCTAGGTGTTAGCCA CAGTGCCCAGCCCCAGTTTCATTTTCTGCAGTTTCAGTTACCCCACAGTCAACCTGGTCC AAAAATATTAAGTGGAAAATCTCAGAAATAATTCATAAGTTTTAATTTGCACACTGTACT GAATAGGGTGATAAAATTTCACTTCGTCCCACCCAGGATATCCATCATCCCTTTGTCCAG TTTATCCACACTGATGCGACACTACCTACCCATTACTATATAGGAAAAAGCATAATATAT ATAGGATTCAATACTGTCTGTGGTTTCAGGCACCCACTGAGGGTCTTGGAACGTATCCCC CAAGGATAAGGGGGCATTATTGTATGCTGATATAAAAATAGCACGAAGATTTATTTTATT TTGTTTATTTTGAGACAGGATCTTGCTGTGTTGCTCATACTAGAGTGCAGTCATGTGATC ATAGCTCATTGCAGCCACCTACTCCTGGGCTCAAGCAGTCCTCCCACCTTAGCCTCCCAA GTATCTGGGACTACAGGCGTGAGCTACCAAACACAGCTAATTTTATTTGGAGAGATGGGG TTTTGCTATGTTGCTCAGGCTGGTCTCAAACTCCTGGACTCAAGTGATCCTCCTGCCTCA GCCTCCCAGAGTGCTGGGATTATAGGTGTGAGCCACTGATCCCAGCCCCAAGATTTATCA TTAAGTTAAAAAAACAAAGTGTAAAGCAGCACAGAGTGTGGTGTCTCTTTCGTTGCCCAG ATTATGCTCTGTGTGAAGTTCAGTTGAGAGGAAGGAGTGGGGAGGGAAGGAGGGAGGGAG GAGGAAGGGAGGAGGAACTCAGACTCAGGCTGTCCTTGGCTGGGCCTGTCTTACTCTAGG CAGTGGTTGTCACAGGACGAGACCCAGCAAACAGTGGAGGAGCTTTTGGCAAGAGACATT ATCAAAGGGATTTACACTTCTAGAGTAGTTGAAATAGAAAATCTCTGCAGTCCTTCCAAA GCCAGGTTTGAGGAGAGGGTGACAGGGCAGGCAGCTGGATGCGGTAGCTAAGAGCGTGAG CTCTGGAATCAGACTTCCTGGTTTAGGATCCCAGCTAGGACCACCTCTGAGCCTCATCTC CCTAAAAGGGAGATATTAATATCATCTCTTGGCTGGGCTGGTGGCTCACACCTGTAATCC CAGCACTTTGGGAGGCCGAGGCAGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCTT GGCCAGCATGGTGAAACCCCATCTCTATTAAAAATAAAAGAATAAATTAAAAAAATAGCC AGGCGTGCTGGCAGGTGCCTATAATTCCAGCTACTCAAGAGGCTGAGGCAGGAGGACTGC TTGAGCCTTGAGGCGGAGGTTGCAGTCAGCCAAGATCGTGCCACTGCACTCCAGCCTGGG TGACAGAGAGAGACTCCGTCTCAAAAAAAAAAAAAGAAAAGAAAAGAAAAATCATGTCTT CACATACTGGTTGTGGGGGACTCTGCAATAAGGCAGTGAAAGCCCTAGCCCAGTGCCTGG CAGCTGCTGTGATGATGATTATTATTATTAATGTCACCCCCGCTCCCCGCCACGCACACA TGGGCTAGAGGGGTGACTTCCACACCCCTGGCTTAGACTGTCCTGCAGGCTGGGTGTTTT CTTTGTGATTCCCAAGGCCCCAAGCCCAGTGGGAAATTTCCGCCACTTCCATGTGCCCTG CCACGACTTCCTGCCATCTGCTGACTCGGTGTGACATGACACACGGCTGCCTCTCCCTGG CCAGCATGGCCGCGGGGCTTGGGTCTGTCTCACTGTTCTTGTTTGTTCAACAGTGGACTC CAACGACAGCCTCTACGGGGGAGACTCCAAGTTCCTGGCAGAAAACAACAAGCTGTGTGA GACGGTGATGGCTCAGATCCTAGAGCATCTGAAAACCCTGGCCAAGGACGAGGTGGGTGC CCTCTGCTGTCCTCCACCCGCCCCTTGCTCTGAAAGCACAAGTTTCCAGGGTGGTTCAAC CTTGGTTCATTCTAGAAAGGAAACTATGTCATGTGAGTAATGTGTTTATGTGCAAACCAC TTCTCCATTGCTTTGGGGCCTTCGCTCCTGCTGTTTTCTCTGCCTGGACTGCGCCTCCCC CAGGGCTTCCCCTGGCTGTTCCTTCTCGTCATTGAAATCTCAGCTCAAAGGACCTCCTCA GGCCTTCCCGGACCCTGTCTGAAGGAGCCACCACCACCTGCATGCCTCTGCCCGATTGTC CCTGTAGCGCCTGTTCAGTCACCGTCTGAAATGTTCTGTCTGTCCATCCCTCAGCTCCCT GACTAGAATGTAAGCTCCATGGGAGCAGGGACCTGGTGAGTCTTTTTTTTTTTTTGAGAC AGTCTCACACTATTGCCTGGGCTGGAGTGCAGTGGCATAATCTCGGCTCACTGCAACCTC CGCCTCCCGGGTTCAGGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGT GCCCGCCACCACACCTGGCTTATTTTTTGTATTTTTTTAGTAGAGATGGGGTTTCACTAT GTTGGCCAGGCTGGTCTTGAACTCCTGACCCTGTGATCCGCCTACCTCGGCCTCCCAAAG TGCTGGGATTATAGGCGTGAGCCACTGCACCCGGCCTGGACCTGGTGAGTCTTGAAGACC TGCCTGTGTCTGAATGACAAGACAGGGACTCTGGGACACCCGGTAACTCTCTGCACCACC CCACGTCTCATGCAGAGCCCGGCCTGCGGCAGATGCTCCATCAGTTCATGGTGAATCCCT GATAGCGTGGGATTGCTATACCTGGGCTCTTTCAGTGCCCACAACAGCCCTGTGAGATGT AGATGCTGTGTTTATTTCCATTGAATGGGGAGGGAAACTGAGGCTCAGAGAGGGTTATTC AGAGCCGTTGATATTTCCTCTGGCTGTGATGAAACAGCAGAGATTCTAACCCGGATTCCC AAACCTGAACTCTGCACTGCTACATTGCCCTCCTCAACCAAGGCCTTTCCACTTCACTTT TCTTTTTATTTTATTTTTTTTGAGACGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCA ATGGCATGATCTTAGCTCACTGCAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCT CAGCCTCCCAAGTAGCTGGGATTCAGGTGCCCGCCACCACACCCGGCTAATTTTTGTGTT TTTAGTAGAGATGGGGTTTCACCATATTAGCCAGGCTGGTCTCGAATTCCTGAGCTCAAG TGATCCTCTTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCTATTGCGCCCG GCCAATATATACCCATTCTGTCCAGGGTGTTCAAGCGTGTGTTTGAGAGAGTAGGATTTT TTCTGGCCTCCAAGTTCAGGGGCACTGCCCGAAGGGCTGGCCTTAGGGTTAGTAGTTGAA AGGGCAGAGACCTACATACCCAACAGTTGCAGAAATGCTGCAGCCCTGGGGGCCCGTAGC ACCTTCTGTAGGGAGGGAGGGTATGTGACTGTGTCCTACTGACCCTGGGGACCCCGAGCT GCAGTACCAGAACTCTGAGCAAGTTAGTGCCTGGAGGGCTCTTGGTTGTTTGTGGAAAGA GTGGCATTGGAACCCCAGTTTCTTCTTCAGGAAAACTGGTTTATCAAACCCGTGAGTATC AGACGAGGCAACTCTCCTAGAATGATTGATACCAGAGGCTGGGAAGGGTATGTGGATGTG TGTGTTGCGGGGGGGCAGGGGAGGGCAATGAAGAGAGGTTGGTTAATGGGTACAAAGATA GATACAGTTAGAAGGAACAGGCCAGGCACAATGCCTCAGACCTGTAATCCCAACATTTTG GGAGGCCCAGGTGGGAGGATTAGTTGAGCCTAGGAGTTTGAGACCAGCTTGGGTAACATA GTAAGATCCTGTCTCTATTAAAAAAAAAATTAAAAATTAGGCCAGGTACGGTGACTCACG CCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGGATCACTTGAGGCCAGGAGTTCG AGACCAGCCTGGCCAACATGGCAAAATCCCACCTCTACAAAAAATACAGAAAAAATTAGT TGGGTGTGGTGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGAAGAATCG CTTAAACCCGGGAGGCGGAGGTTGCCGTGAGCCCAGATCATGTCACTGCACTCCAGCCTG GGCGACAGAGTGAGACTCCATCTCAGAAAAAAATTTTAAATTACCCGGGCGTGGTGGTGA GTGCCTGTAGTCCCAGCTACTGGAGAGGCTGAGGCGGGAATTGAAGGCTGCGGCGGGAAC TCGAGGCTGCAGTGAGCTGTGATCATGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGA CCCTGTCTCCAAAAAAAAAGAAAAAAAAAAAAAAAAAGAAAAAAGGGGGAATAAAAGGGA ATAAGTTCTAATGTTCAATAGCAGAGCAGAGTAACTACAATTAACAACAGTGTATTATAC ATTTCAAAATAGCTATAAGAGAAGACTTGAAATGTTCTGTACACATAGAAATGATAAATG CTTAGGCGACAGACACCCCAAATACCCTGGCACAATCATTGTAATTCTAGGCATGTAACA AAATACCACATGTACCTCATAAATACACACAAATATTATGTATCAATAATTTTTAAATGT TGCATATCTGAGGCTCATGAATCAAGATGAGAAAATAAAACCCTAAATACACATTGTTTT AAAAGACCTTTTACAAACATGCACAAACACTCAGCAAGGGTTCATACCTCTTCCGTTTTC TGTGTAGATGGTTTTCAGGAGAGAGCCCTTTCAGCCTACAGGAATAATGGAAGCCCATCA CCTTTAGCTTGTACTAATTAGATCCCCCCAAGGAAAGCTTGTCTTAGCTTTTTCCCCTGA TTTCTTTTCTTTTTTTTTTTTTCTTCCAGAGACAGGGTCTTACTCTGTCATCCAGGCTGG AGTACAGTGGCACTACCTTAGCTCACTGCAGCTTCAACCTCCTGGGCTCTAGTGATCCTC CCATGTCAGCCTCCCAAGTAGCTGGGACTACAGGCATGTACCACCACACCCAGCTAAGTT CTTATTTCTTACACAGCCGAGGTCTCTCTGGGTTGCCCAGGCTAGTCCTAAAATACTGAG CTTGGCCGGGCACGGTTGGCTCATGCCTGTACTCCCAGCACTTTGGGAGGCTGAGACAGG CAGATCACTTGAGGTCAGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCACCTC TACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCAGCTACTTG GGAGGCTGAGGCAGGAGAACTGCTTGAACCCAGGAGGGGGAGGTTGCAGTGAGCTGAGAT CACGCCACTGCACTCCAGCCTGGGTGACAGAACGAGACTCTGTTTCAGAAAAAAAAAAAA AAAAGACAGAGCTCAAGTGATCCGCCCACCTTGGCCTTGGGCTCCCAAAGTGCTGCGGAT TCTGGGCGTAAGCCGCCATGCCCAGCCTTCCCCTGATTTCTTGAAACCATTGGTTCTGGC TCCGCCCTCTAGTCCAGGGACCTCTTAGAACAATGATGTGTGTTTGACAAGCCACACCCA CAGAACACTTGACATGTGGTTCAAAATTACGTGTCTTCATACCGAGGCAATAGGCTGGGT TTAATCAGAGGTGGTCACTGACAGCATAAATGATCATAGCCCAGAAGTCCCAAGCTTGCA AGAAAAATAAAGCCCAGAACCATATAATTTGGAGCTATTTATATTTAACATTTATGTCTC TTTCTCTGGTGGAGAGAGGGGTTGATGGTGATAGTGATTCTGAAAGAATAGCAAAGATGG AATGTTTCTGAAGAACATTTCACGTGGCATCAATACCAGCGATGTTCACTGAAAATGTCT GTCCATATGTGCACATTTATTAGAAAAACATCGGTCAGGCATGGTGGCTCATGCCTGTAA TCCCAACACTTTGGGAGGCTGGGGAAGGAGGATTGCTTTATTCCAGGAGTTTGAGACCAG CCTGGGGAACATAGTAAAACCCCATCTCTAAAAAAATTTTAAAAGTTAGCCAGGCATGGT GGTGTGCACCCTGAGTAGCTGGGACTACTCAGGAGGCTGAGGTGGGAGGATCGCTTGAGC CCAGGAGTTTGAGGCTGCAGTGAGCTGTGATTGCACCACTACACTCCAACCCTGGCAGCA GAGCAAGACCCTGTCTCTAAAATAAATAAATAAATAAAAACATGGTCATATGGGTGGACC AAGCTGAAACTGAACATGTTATCCTTCTTTTATTTTATTTTTTTTTTGAGACAGTCTTGC TCTGTTGCCCAGACTGGAGTGTAGTGGCACAATTTCAGCTGACTGCAACCTCCACCTCCC AGATTCAAGTGATTCTCCTGCCTCAGGCTTCCGAGTAGCTGGGACTACAGGCGCGTGCCA CCACACCTAGCTAATTTTTTGTATTTCTAGTAGAGACGGGGTTTCACTGTTAGCCAGGAT GGTCTCGATCTCCTGACCTCATGATGCGCCCGCCTCAGCTTCCCAAAGTACTGGGATTAC AGGCATAAGCCACCGTGCCCGGCTATCCTTTGTTTTAATGGTGCAATTTGAAGTTCAGCT CAACAGCCATACTGGAGTCCTCTGAAGTCTGGTACCCCAAGAGCATGAGGCTTGGTATCC AGGCCCATCACAGACCAGGAAGGGCCTGGTGGATTTCTCCCCACTGAGTGGGGTGGGCGG CTTCTTGCTGTTGGAAAACCCTGATGCCTGTGCCGTTCTGAGAATCATATCGCAGCTCTG GTAGCAACCGTGCTTCCAAAGTCATCCTCTAAGGCCACGTGAAGGTGCCAGCCTCATTTT AATCACAAGCTGTATTTTATGAAGTTGTTTGTTTGGGTGTGGTGGAGCTGGGAACCATGC CAAACCCCGAGAGCTTCCTGGAAATGACAGTTCTCATAGGAAAAGCAGCTCTTTTCTATT TAAAACCTCTGTGGCGAGGGGAGGGGATCAGGCCCTGATTTGGTTCCCAAGCTACGTGTT TGTATTTTTCTCGGTGTTTGAATATATCAGCTGGCATGTGTCTCATCCCTCAGACACGTC TCCAATGATTTCACTTTTAATGGGCTTTGGCATTTAAAACACATGCGAATTGAGCTTTTT GCTAATTGAGAAGATATGGAATGGAGAAATAGCCAATTAGGTATTGTGCTGCTTGTCTGA CTTTTAAAACAGTTTCTCCCACTTCAGTGAAAGGTAGTCAAAGGGCCTCTCTCCAAGGAG ACTTTTAGTTAGCTCTGAAAGAGTTTTATTTTAGCTTGGTCTTGTAGATTCAGGCAGAAA GTGGGGCTCCCGTTCTCCCAGGTGTCAGACGAGGACCAGGTTAAAAGGAGAGCAGGATGG GCTCAGGTTCCCACTTGGGGCATAACTGCATTGTCTGTTAGAACAAATGAAGGCAGAGCA GGTGGTCGCCAGCCAGTTTGCGAGTCCGTGCCCAGCAGGTGCCAGCCCGCGTGCCCTGTG CCAAAGCGCTTTTCTCTTGTAGCCCGCGGGCCTGGGCGCCCACAGCACAACCTGCTCCCT GATGATTGGGCTCTTTGCCGTCGGCTCTGCTGCTTCTGTGACTGTCGCTGCTCTAGGCTG TTGCCAAGGCAGGCTCAATTTTGCCCGGAGTGGGGAGGGGAGGTGCCGAAGAGTCTTAAT TACCACTCAGCCACCTTGCCCAACTGCATTTGAAGCTGTTCCTTGACTTTTTCTTTAAGA CAGGGTCTTGCTCTGATGCCCAGGCTTGAGTGCGGTGAGATCATAGCTCACTGCAGCCTC AAACTCTTGCCCTCAAGTGATCCTCCAGCCTCAGCCTCCTGAGTAGCTGGGACAATAGGT GTGTGCTACCATGCTCAGCTAATTTTTTTTTTCTTTTCACTAAAAGACTTTAAATTCTCA CTTGGGAAAGGACAGTAAGAAGGGGTAAATCAGTTGGCATAGCAGCTCGCAGGCGCCATG TGAATTATCTGTGGAACGTTGGATGGATAGACGGTTGATAAGTTGGTTTTAGCCACCGAG AGTAGTTGAGAAAAGCAGGAAGAAATGTGTTTTGGTGTAAGCCCAATCAAGCCATTCTTA ATCCCTGCATACAACTGCATAGCCAAAGTTGGCTCATGGCACTGGCAAGTCAGCCCTTTC TGAGTGCGATTCCTGATAAGATGCGACCCTGAGTGTGTGGCCTGGAGAGGGCTGTGAGTA CGAGCACAGGCTCTGGAGTCAGAGAGCTGGAGCTCGGACTCCCCTCTGCATTGTGAGGAC CCATCTGTGGTCCTTGGGCAAGTTCCTAACCTTTCAGAGCCTCAGGTGCCTCATCTGCAG AATGGGAGCATATTCATTTCCTGTTGCCACCATAACCCGTTGCCACAAACTTGGCATCTT AAAGCAGTACCCATTTTTGATCTCACTGTTTGGTAGGTGAGAAGTCAGTGCTAGCTGGGG CCGGCGTCTCTGTTCTGGGTTTCACAAGGCCAGAATCAAGGTCTTGCTGGCTGGGCTCTT ATCAGGAGGCACTGGAAAGAATCTACTTCCTTGTTCCTTCAGGGTATTTGCAGATTGCAT TTCCGTGTGATCATGGACTGAGATCCTGTGTCTGTTGGCCAGGTGTCCTTCTCAGCTTCT AGAAGCTGTCTGTGTTTCTCAGCTCATGGCCACCACTGGTGGCCCAGGTTCTCCTCATGC CTTGAATCTCTGGCTTCCCTTCTTCCTCCTCTTTCCTGTTTTTCTCTTCCACTGCTTGTC TCTGATTCTGGTCGGAGAAATGCTTCTGCTTTTAAGGGCTCCAGTGATTCGAGGGCCCAC TCAGGTCATCTAAGATATGCTCCCTACCTTAATTCCATCTGCAGTCTCTCCACAGCAGCA CCGGGATTCATGTTTGAATAACGGGAAGGAATGCTGGGGGACACCTCTAGAATTCTATCA TGGGCGGTTAGGAGTGTACCTGCCACGGAGCTGTCATGAAGGTTAAATCACGCGAGTTGT ATAAAGCACAGAGCAGAATCCCTGGCACACTCTTAAGGGCTCTTACACGCATTCACTGTC AGGGAGCAGACATGAGACTCTTGGCAGCACTGATGTTGTGCAGATGTGGGATCTGCCGTG GCCCCATGGGCTTCCTGAACAGCAGGTACCCACCTGTTGATGTGGCTTTTCCAGGGGCCT TCGTTTACCTTGGGGAAGTTGTATCCTCTCTCCTGGGCCTGGTGTTGCATTCTGGAGATT TATTTTCCCTTTTGTCTTTATCACTCAAAGCTGGAGTTCAGGTTCGGTCTGCCGTGACAC TGTGGTTAGACTTTTTTTGGCAAGATACCTCTCACATCAGATGATTGAGCAAGAAAGGAA AGATCTGATGTCAGCGTGTAAAGGCTGGATATGGGCACCAAGGATTGGGGAGCTCAGTTC GGGAGATGTGTTTTGGTCTTTATTACCGGCAGCCCAGGGGCAGGAATACTGACTGCAGCT TTGGGTAGTTTGAGGACACATCTGAAAGAGGTGAGCTGAAGCCTTTCAGTTTTCAGCTGT ACTTGCATTAAAGCAAGGCTTGTCCCTGCTGGGGTACCCTTCATTCCTCGACCTCACTGA CTGGTGAGTTTCTTCCATTTCATGAGTAATGACCATCTGTGGGCACAGAGCTTCGTCATC TTACTGAATCCCCGCCCTTTGCAGGGGTGACCTTACTGTCACTTACAGATGAAGCAGCTG GGACTTTGGGAGGTTCAGCAGCTTGCCCTACAGCAAATACATGGCAGAGCTGGCACTGGA ACTCAGGCATGACCTACCCCAGAGTCAGCACTGTCCACAGCATCTCTGCGGGGCACGGCC TGAGCCCCAGTGCAAGGCAGTAACCTCCCTTTTCTGTTTCAGGCCCTGAAGCGCCAGAGC TCGTTGGGCCTTTCCTTCTTTAACAGCATCTTGGCCCATGGGGACCTACGCAACAACAAG CTCAACCAGCTCTCCGTCAACCTGTGGCACCTGGCACAGAGGCACGGCTGTGCAGACACC AGGACCATGGTGAGGCGCTCGGAGGGCCCCGTGGTATAAGCCCACTGGCCAGTGCACAAC CACCCTCAACACAGCATTGTGGCCTGGACATCAGACAGACAACCCCATACTCCCCTTTTA GAAAAGCACTTGGTCCATTTCTACTGGATCACTTCCTAGCAGTAAAAAGCAGAGCTGGCC AGGTGTGGCAGCTCATGCCTATAATCCCAGCACTTTGGGAGGCTGAGACAGGAGGATCGC TTGAGGCTAAGGGTTTGACACCAGCCTGGGCAACATAGTGAGACCAGGTCTCTACAAAAA ATAAAAAATTAGCCGGCCATGGTGGTGCACATGTGTAGTCCCAGCTACTCGGGAGGCTGA AGAGGGAGGATGGCTTGAGCCCAGGAGTTCGAGGCTGCAGTGAGCTATGATCACACCGCT GCACTCCAGCCTGGGTGATAGAGCAGGACCTTGTCTCCAAAACAAAGAACAAAAGCATAG CCTTAAAAGTCTATTCCCTCTGAATAGGAACCATACATACAAAACATCAGTCATTTCTGG TCACGTCCAAATCTGATTTTTAGGGCAAGCTGCAATCCAAGAAGTTGAAGACTTTGATTT CTTCCCTCCTCTCATCCCTCAAAAAACTCACTCTTCTCTGCTAAGAAATCTAAGCTCACA TAATGGCTGATTCATTAGAGCCTTGGGCTCCAAGGATAATGAACCAGAAAGGAGATGGAT CTTTCTTTTTCCTCATAGGTGAAAACGCTAGAATACATCAAGAAGCAAAGCAAACAACCA GACATGACTCATCTGACGGAGCTGGCCCTCAGACTCCCTCTGCAAACAAGGACCTGACCC CCGGGCCCATCCCCAGGCTCAGGGACTCTGGTGCCAAATCCAGAAAGATCTGCTCTGCTG CCCTGAACTCTTACGGCAATTTAGGTTTCTCATTTTTCTTTTCTTTTTACATATGTACAA ATTGTTTTAAGCTTTGGCCTCTATCCAGGTTATTCTGACAATGAAGAAATGGGAGTTGTC AGAGCATTAAAATGCAATCTTCACTAAGAAGCAGTCTCTGTGTTGTCTTTGCACAAGTGG CCTTCGGTCTACTCAGCCCGATCTGATGGGCCTTTTTAGCAAGAGAGAAACAAGAATGCA AGTAACATCTTTCTTCTCTGGAAGGTGTTTGTTTTTTCATAGTTTAGAAATAAGGACTTT AAAAGTGGACTGCTTTTCAAAGTGCCACTGTTCCAGACCCATTCCATTCCAGACTTTGTA CCTTAAAGTTAGAGCACACCCAAAGTCTGGAACTGTGTTACCTGAACCCCTATGGAGGAT TTATAAAAGGCAGAAATAGCACTCCATTAACTCTTTTTCCTATCAAAAGCAGCTCTTGAT TGGACTTAGAATCTGTGTTGGTGGATCAAAGGAGAAAGCGAGGTCAAATTTGAGATTCTC TGTGGCTTCAGTATACAGTAACTGAATAAATGTCCTGAAGGAGCATTTATGTTCATGACT GTTCATTTAATTACTTCTGACTGTCTTCCTCCAGAAGAGAAAGACCGTGTCTAAATATAT TATCCTGGTTTGTTTTGCAGCCACAATTCTAAACAGCATGTGATTCTGTCTGCTTTTCTT CCAACAGTTTGGTGGAACCTGATTCTTCTATTACGGCTGGTGAGCTTGCACCGACATTTC ATTTTGAATCAGTAAAAACATTCATACTGATGGGTGATTCATCATCTCAGCCACTGCCAT TATGAAAATGCATCCACACTGTGGATTAAAAATGCCCCAAACTATTGTGCTTCTACAAGA TCCACACTGGAACTGGACATAGATTACATTTCATCTTTACTCTGAGAAATACAAGACTAC AGTTGAACACTCAGTTAACCTCAGACAGTAAAAGGGGCTAAAAAATTTTTTTAAATCAAT TTATTGGCCGGGCACGGTGATTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAG GCAGATCACCTGAGGTCAGGAATTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCT CTACTAACAATACAAAAATTAGCCAGGCGTGGTGGCACACACCTGTAATCCCAGCTACTT GGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGA TTGCGTCACTGCACTCCAGCCTGAGTGACAAGAGCAAAATATCATCTCATCTCAAAAAAA ATTAAAGGACAGCAGACACTAATGAATGCTTCTTTCCCTCCCCTCTACTAAATCATACAG AAACTCAGACAGCATTGTGGGGTGGCTCAGATACTCCCAAGTGGCCTTTATTTCACAAAA TTCTGTTTTTTTTTCTTTTTTTTGAGACAGTTTCACTCTTGTTGCCCAGGCTGGAGTACA ATGGCGTGATCTCGGCTCACCCCAACCTCCGCCTCCCGAGTCTAAGCAATTCTCCTGCCT CAGCCTCCTGAGTAGCTGGGATAACAGGAGTGCGCCACCACACCCAGCTAATTTTGTATT TTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTAGAACTCCTGACCTCAGG TGATCCGCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCACCGCACCTGG CCCACAGAAGTATTTTCATTAAAATTATTTTATCTACTTTTACTGTGTGATGCTATAAAA TGAAAAACAATTGGCAAATTCACAAATTATGTTCTTCAAGTCATTTCTTCTCCTCTGAGG CTGAACGTGGTGGGCAGCATTAGTTCCCAAGCCTAGGCCAGTGAATTCTTACCGCTCTCA CATTACACCTGAACTTGGACTTTCACATGAGGTCGGGCACCCATTATATCAAAGGTGCTT CTGAATCCTGTCATGTGGCCCAGGCAGAGGCTTAGATTTTATATGTCCTTGTGTGTGCAG TTTCCCCCAGCCCTTTACTGAATCAATAAGCCGGTCTCTGAAAACACTGGTCTATGTGAG ATGAAGTCTATCATTAGCAAGGATGGAGCAATAAGATGTCAGCCAGAATTGTAGAAAATA AAAATGATGGGGCCTGGGTGCGGTGGCTCATGCCTGTAATACCAACACTTTGGGAGGCTG AGGTAGGTGGATCATGAGGCCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACTCC ATCTCTACTAAAAATACAAAAAAAAATTAGCTGGGTGTGGTGGTGCTCACCTGTAATCCC AGCTTCTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCTGGAGGTGGAGGTTGCAGTG AGCTGAGATCACGCCTCTGCACTCCAGCCTGGGCGTGGAGTGAGAGTGAGACTGTCTCAA AAAAAAAAAAAGAAAGAAAAACAAAACCATGGCAACTTCCACATGAGACTTACTTACATT AGGTCTTCTATTGTTACTTTAACAAATTGCCACAATTGTAGCGGCTTAAAACATAATGTT GTCATCTGACGGTTCTATAGGTCTTAAGTCCGCCTGGTCTCACTGAGCTAAAATTAAGGC ATCAGCAGGGCTACGCTCCTTCTGGGAGGCTCTAGGGGAGAATCTACTTCCTTGCCTTTT CCAGCTTCTAGACAGCACACACATTCCTTGGCTTCTGACCCTTCCCTTCCCATCTTCAAA ACCAGCAGTGTCTAGTCAAGTCTTTCTTAAGTCTCTTTGATGTGGACTCTTTTTTGCCTT CCTCTTCCACATTTAGGGATCTTTGTGATTCCTCCGGCCCACCCAGAAACACGGGATCCT CTTCCTGTTTTAAGGTCAGCTGATTAGCAAACTTAATTCCCTTTTGTTTCGTAACCTAAC AAATACACAGGTTCTGAGGAGATGTGGTAGGAAGGGGTGTTATTCTGCCAACTTCTTTTG TGAGGACTGTGTCTATTTGGCAAATTTTTTTTTTTTTTTGGAATGGGGTCTTGCTCTGTC ACCCAGGCTGGAACACAGTGGTGCAATCATGGCTCACTGCAGCCGTGATGGAGGGTGGTG CTCAAACCAATGTTAATTTACAAAGGATGGGAGCTCAGAGTGATTCTCCCAAGACAAGAC TGCCAGAGGGTGGGGTCCTGCTCATCTGAGAGATGGTGATCTGCACTGGCAGAAAGCAAA AGGACAAGATTAAGTCCATTCTGAAGACACCCAGCATTGTGGTGTCTTGGCTGCCCAACC TCCACTGGTGAGACGTAAAGTTCTTATGTATATAGAAAAGCAATAAAGCTCCCCCTGTGC AAATGGAACTCCTAAGCCAGTGGTGATGTTGAGTTAGAAAGTCACAGCCTATTACAGACA GAATTTACACCAGGGGCAAGGCCTGACCATCACACCCTCATGAGAGCTACCAGTCACCAG GGCTTGGATGGGAGCAACACAGCGGACATATGATCACCTCTCCACAATCACCCAAAGACA GTTTTTTTTTGTTTGTTTTTGAGACAGAGTCTCATTCTGTTGCCCGGGGCTAGAGTGTGC AGTGGCACCATCCCAGCTCACTACAACCTCCACCTCCCGGGTTCAAGCGATTCTCCTGTC AGCCTCCTGAGTAGCCGGGATTACAAGCCCGTGACACCACACCCACCCAGCTAATTTTTG TATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCTTGACCT CGTGATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGCACC TGGCAGAGCACAACCTTTTTAACAGAGCTAAGGCAGGCCAACGTCAGGGTGACCTCTTGG CAAGATAAAAACTATGAGTAGTAAACGGCCGATTCCAGCTACTCAGGAGACTGAGGCACA AGAATCGCTTGAACCCAGGAAGCAGAGGTTACAATGAGCCGAGATCACGCCACCACACTC CAGCCTGCGCGACCGTGAGACTCCATCTCAAAAAAAAAGAAACGAACGGCTGGTTCCTGT TTACACCAGGCACATTCCTGTAGTGTTGCTCAAGGTCAGGAGGGATTTGTTTCTCCATCA AAGGAGGAGGTGCCCAGAAGGCACTCACTCAAATCCAGAACACTGCCTCTTGGGCTTTCC ACGGCCTCTCCCATTATGTATCTCAAGGTTGAATCCAGGAAAGAAAGGCAGGACAAGTTC ACGTCCTGAGGGAAGTGGCCCAAGTAGGTCCTTGTAGCACATACTTGTCCAACTATTGAC CTGGCCAATGCTTGCGGATCAGGGTTCAGAGCCAGGGAAACTGCCTGAAGTGCCTGCCTC ACCTCTGCCCAATGGGCAGCTGTGGACACCATGGCCACTTCACCAGCATCCACTCTTCTT GACTGAAGGGAATCACCAGCCTTCCCATGACAGGGGCGGGTGCAGCTATGGGCAGATGAC TCATTGCCCAGCAATGGAGGCTTCTGGAAGTTTCCTTGAGACACAAAAAGGCTTTTCTTC CTCTGGAATGTTCTAGGGTCTTGATATGCTGCCTGGAACTGTTACTGCCATCTTTGTACT AGCCTTGATGAAGCCAACACTGGAGATGATGGAGAGAATGCTTCCTTGGCGAGCTGTTGA ACCAGGCCCTAATCAGGCCTTCCTGCCACGTGAGACTGAACTTTCTGGCCATCGAGGCCT GCCTGGGCTGGGATGTCTGTAGGAGGCATGTTCAGGCCAAACGATCGTGAAAATGTCCCA GTCAGAACCTGTATTTTGGGATGCAAAAAGCTAGGTGAGTGGAAAGAAGGTGGTCACAGA TGGTCACATGCGACTTGGGCCACTGGACCTGGAGCTCTTTGAGGCTTGCTGTAGAGTCCA GGCTTGGAAACGCTGTCCCCACAGCCGATGAGGCAACTTCCCGTGTCATCTCCACACGTT CATCTCCTCCTGGCATTCAATATCCACCTACAGAAGTCACCTGGGATTCTCTTCCTTGTG ATAAAAAAGAATCTCATCAGACACATCCCTGGGGCTGGGCACAGTGGCTCACACCTGTGA TCCCAGCTCTTGGGGGCTGAGGCAGGAGCATGAGTTGAGTCCAGGAGTTTGGGACTAGCC TGGACAATATAGTGAGACCCCATCTCTACAAAAAATTTTAAACACTAGCTGGTTGTTGTG GTGCACACCCACAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCACTTAAGCTGGA TAGGTAGTGGTTGCAACAAGCCGTGATATGCCACTACACTCCAGCCTGGGTGACAGAGTG AGAGCCTATCTCAAAACACACACACACGTCCCTGGGATCTGCCATTGATTCATTTGCGGG ACTAACCACTCTTCCTAAAATGCCTTGTTCAGAATCCAGTCAAAGCACAAAAATCCTACC TCAGCACTTAGGGCCGAAGGGACACCAGTGGAAAAGGCAGGACTGGTTTAGAGGCACATT TCCCAGCAGCAGCAGCTCAGTCACATGTGTTTGGTAACAACTCAGACACCTCTCTGCCTA CAGCTGCTCTATGACAGGGGAAAGGAAAAGGAAGGAAAAGGAGTTTGCGATTCTCCGTTC CTCATTCACTCCACTTTTTATCAGAGATGCAGACTTGTCATAAAACTTTTTCCTCCATCT AAAGACATTTCAATCCCCAACGAGGATTCTGGTGGAAATTCCCTAAAGGGGACATTCAGA GTGGCGAATAGTGAACTTAGGGCTTCGGGTACAAAAGTACAACACCCTGCACTTAGTGGC TGGGTGACCCCAGGCAATTTTATTACTTTATCCCTGAACCTCAGTTGCCTCATCTATAAG ATGGGGCTAATAATAGCACCCATTTCATAATTATGAAGATTAAATACATTAAGGAAAACA CTAGTATGTCCCTAGTACCTGCTAAACACTCAACAAAAGTTAACTGTACATACTGATGTC TCAAACAGGGACGGAATGTTTAACACAGAAAACAGGAGGTTTTAGCACTCACTCGTTCTC CTGGCTCCCGAAATATGAGCTGCCCTGCCCCAGTTCATCCAAGCCCATCAATATAGTTGT CCTCGTCCTTAATCTCCACAGGTGTTCAATGTGAGCCAACTGTCAGATGGCTTTCATTTG CACAACTGAATAAACCATTTATGCCTAGTGTTCCATTACTGGAACGCTAAGCTTATGGGA GTTATTTATATCTTACTGCTCGAGGTCCTCACCA bcftools-1.21/test/csq/ENST00000448695/ENST00000448695.fa.fai000066400000000000000000000000231467060157400215620ustar00rootroot0000000000000016 151594 25 60 61 bcftools-1.21/test/csq/ENST00000448695/ENST00000448695.gff000066400000000000000000000201671467060157400212130ustar00rootroot0000000000000016 ensembl_havana gene 21 151574 . + . ID=gene:ENSG00000103544;Name=C16orf62;biotype=protein_coding;description=chromosome 16 open reading frame 62 [Source:HGNC Symbol%3BAcc:24641];gene_id=ENSG00000103544;logic_name=ensembl_havana_gene;version=10 16 ensembl_havana transcript 23766 145465 . + . ID=transcript:ENST00000448695;Parent=gene:ENSG00000103544;Name=C16orf62-203;biotype=protein_coding;tag=basic;transcript_id=ENST00000448695;version=1 16 ensembl exon 23766 23909 . + . Parent=transcript:ENST00000448695;Name=ENSE00001647011;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001647011;rank=1;version=1 16 ensembl CDS 23766 23909 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 26306 26434 . + . Parent=transcript:ENST00000448695;Name=ENSE00003583820;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003583820;rank=2;version=1 16 ensembl CDS 26306 26434 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 32174 32179 . + . Parent=transcript:ENST00000448695;Name=ENSE00001690913;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001690913;rank=3;version=1 16 ensembl CDS 32174 32179 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 46450 46504 . + . Parent=transcript:ENST00000448695;Name=ENSE00001713400;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001713400;rank=4;version=1 16 ensembl CDS 46450 46504 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 52959 53055 . + . Parent=transcript:ENST00000448695;Name=ENSE00003631395;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003631395;rank=5;version=1 16 ensembl CDS 52959 53055 . + 2 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 53755 53802 . + . Parent=transcript:ENST00000448695;Name=ENSE00003682253;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003682253;rank=6;version=1 16 ensembl CDS 53755 53802 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 55103 55196 . + . Parent=transcript:ENST00000448695;Name=ENSE00003516770;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003516770;rank=7;version=1 16 ensembl CDS 55103 55196 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 60895 60972 . + . Parent=transcript:ENST00000448695;Name=ENSE00003547874;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003547874;rank=8;version=1 16 ensembl CDS 60895 60972 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 61467 61589 . + . Parent=transcript:ENST00000448695;Name=ENSE00003596287;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003596287;rank=9;version=1 16 ensembl CDS 61467 61589 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 70958 71004 . + . Parent=transcript:ENST00000448695;Name=ENSE00003589693;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003589693;rank=10;version=1 16 ensembl CDS 70958 71004 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 72475 72586 . + . Parent=transcript:ENST00000448695;Name=ENSE00001667879;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001667879;rank=11;version=1 16 ensembl CDS 72475 72586 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 73418 73534 . + . Parent=transcript:ENST00000448695;Name=ENSE00001740172;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001740172;rank=12;version=1 16 ensembl CDS 73418 73534 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 74548 74601 . + . Parent=transcript:ENST00000448695;Name=ENSE00001653861;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001653861;rank=13;version=1 16 ensembl CDS 74548 74601 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 77873 77953 . + . Parent=transcript:ENST00000448695;Name=ENSE00001650977;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001650977;rank=14;version=1 16 ensembl CDS 77873 77953 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 82375 82437 . + . Parent=transcript:ENST00000448695;Name=ENSE00001669194;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001669194;rank=15;version=1 16 ensembl CDS 82375 82437 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 84796 84881 . + . Parent=transcript:ENST00000448695;Name=ENSE00001665698;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001665698;rank=16;version=1 16 ensembl CDS 84796 84881 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 87177 87257 . + . Parent=transcript:ENST00000448695;Name=ENSE00001804934;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001804934;rank=17;version=1 16 ensembl CDS 87177 87257 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 89667 89730 . + . Parent=transcript:ENST00000448695;Name=ENSE00001634343;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001634343;rank=18;version=1 16 ensembl CDS 89667 89730 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 92565 92663 . + . Parent=transcript:ENST00000448695;Name=ENSE00001614851;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001614851;rank=19;version=1 16 ensembl CDS 92565 92663 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 95163 95240 . + . Parent=transcript:ENST00000448695;Name=ENSE00003460599;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003460599;rank=20;version=1 16 ensembl CDS 95163 95240 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 96757 96871 . + . Parent=transcript:ENST00000448695;Name=ENSE00003580628;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003580628;rank=21;version=1 16 ensembl CDS 96757 96871 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 113941 114080 . + . Parent=transcript:ENST00000448695;Name=ENSE00001599382;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001599382;rank=22;version=1 16 ensembl CDS 113941 114080 . + 2 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 127006 127171 . + . Parent=transcript:ENST00000448695;Name=ENSE00001690657;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001690657;rank=23;version=1 16 ensembl CDS 127006 127171 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 136134 136252 . + . Parent=transcript:ENST00000448695;Name=ENSE00001730354;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001730354;rank=24;version=1 16 ensembl CDS 136134 136252 . + 2 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 144283 144429 . + . Parent=transcript:ENST00000448695;Name=ENSE00001672058;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001672058;rank=25;version=1 16 ensembl CDS 144283 144429 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl CDS 145159 145257 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 16 ensembl exon 145159 145465 . + . Parent=transcript:ENST00000448695;Name=ENSE00001715916;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001715916;rank=26;version=1 16 ensembl three_prime_UTR 145258 145465 . + . Parent=transcript:ENST00000448695 bcftools-1.21/test/csq/ENST00000448695/syn-and-splice-reg.txt000066400000000000000000000004051467060157400230250ustar00rootroot0000000000000032176 T C splice_region|C16orf62|ENST00000448695|protein_coding,synonymous|C16orf62|ENST00000448695|protein_coding|+|92A|32176T>C 32176 T C splice_region|C16orf62|ENST00000448695|protein_coding,synonymous|C16orf62|ENST00000448695|protein_coding|+|92A|32176T>C bcftools-1.21/test/csq/ENST00000448695/syn-and-splice-reg.vcf000066400000000000000000000010201467060157400227560ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 16 32176 . T C . . EXP=splice_region|C16orf62|ENST00000448695|protein_coding,synonymous|C16orf62|ENST00000448695|protein_coding|+|92A|32176T>C;type=ENST00000448695:19598717-T-C, VEP thinks this is not splice region, why? bcftools-1.21/test/csq/ENST00000479739/000077500000000000000000000000001467060157400166675ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000479739/ENST00000479739.fa000066400000000000000000001406041467060157400210440ustar00rootroot00000000000000>2 2:217710-266418 GGAGCTGGGGCTGAGCGGGCAGCTCGCTTCAGGGTGGGCATGGGGGAGCGCAAATATTGG GTCAGCGAGTGTCTGAAAGGCAACAGAATCTCTGGTGGATTTAATAGAGGGCATGAGATA GAAGAACGAAAGTTGGCTCTGAAGTCACCCTGAGGACCAAGGAAATCCAAGGATGGAATT TCCATTTACTGAAGAGGAACACTGTGGGAGGGGCAGGCTAAGTGAGGAGAAAGAAGAGCT TGGATTTGAGCCCGTGAAGGCTGAGGTGTTGTTCCTTGTCCAAACGGAGCTGTAAAGTGC ATAGCTGGAGAGGGGAGTCTAGAGTTCAGGAAGGAGCTCAGGCAGCCCAGAACGGAGGTG GATTTCACCCTGCATATGAGACATAGGACTTCTGCCTACCTTACAAAAAAAATAAGAAAA ACAAAATTGAAATATTAACTTAGTAAACATTTAAAAATTTTATTTAGAGACAAGTCTACC ATGTCACCGTAAGTTTATGCTACTGCTGGAAATGAACAAATGTAGCCCCATAAGGAAGAA AAGTTGAGAGATGCCATATGTTTAAAGACATGGTAGTCAGACTTCTTTGTAATCACATTT CTATGATAAATGCATAGTATAATTTTTGAAGGTATAAAGACAATTTCTAAGGATTTATAT TCTAGTTAATACCTACGACTCTAAACATTACTTAATACCTCATTTAAGCTGATTTCTTTT TCTCTAGTCACTTTGCAAATGGAAATGTAAGAATTGAAATTTGTGGCTCTACCCTCAAGA TTCTCAAATTAAAACACAGCTACCATATACATGGCCAGATCAAATGCTTAGCGATGTTTG AAGTGTTCACAAGAGAACTATGAGCGTATAAACTGTATGATATTCTATGACACAGTAAGT GTGATAAAGTTAGTACAAAGTATTTAAAGATATGTCAGTCAGCTCTTTTTATATAGAAAA ACAAAATCTTTTACATACGGAATGGAAATTTTGTAGAACAGAAGTTTTTTAAAATTTATA TTAAACATTGCTTAACTAGTAAATCCTGTCAGTGTAGAAATAATTTTTTTGTAATTCTCA AAGAAGAAAATAGTATACGCTTTAATTCATGGTTACGTAGTTGGCTGGAAAAATGCCAGT TTGACCTCGAAGTTTTCCTTCCCACCAATCAAAATGTGAATCTGTTTTTGATATAACTGT GATTCTGTCTCCAGCTTGAAAATTCAAATCCCCAGGCTGCTGTCCTTCAAATGAATACAG CGCTGTCACTTCTATGGGTTGATTCAAATTGCCTGAAACAAGAAAAAAGTATTCACGTTT ATGTTCTTTAAGGGAGAAATTGGGGGTATCTGCTGGTAAGATAAAAATTAACCACTTAGG GCTTGGCATGCTGATGTCTTGGAGGCTGGCAGAAACCACAACAGTCTGTGTAATTTTCAT CACATTATTAAACTTATTTTTCTCTGCACATTCTATACCTAAGGATTTAGCACATGCTTC TGGTTACAATCGTCTAAATTTTGAATAATCTATGAGATAATACAACTTACATTTTTTCTA TTTTAATATAGTCATTGCTGTGGTCTGAATGTCTGTGTCCCCCTGAGATTCAAGTGTTGA AATCCTCAACCCCAAGGTGATGGTGTTAGAAGTGGGGTCTCTGGGGGCTGATTAGGTCAT TACGTTTCCCCCTCATGAATGGGATCAGTGTCTTACAGACAGAGCCTGAGGGGAGCTTCT TGCACCTTCCTCCTTGTGAGGACACAGCCAGATGGCACCATCTCTGAGGCAGAAACCGAG ACCTTGCCAGACACTGAGTCTCCTGGAACCTTGATCTTGGAATCCAGCCTCCAGAAGCGT GAGAAATAAAATTCCATTGTCTATGAGCTGCCCAGACTATGGTGTTTTGTTACAGCAGCT GGAAGGGGCCAAGATAGTGTGACAGTTTCATGGATGGCAGATGCTGGAGAAAGGCAGATA TGTGAGCTTATATCAAACCCTAGGAGATTCAACTTTAAAACCTGGCTCTTTACTCACTGG GCTTGAAGATTGCAGCCCAGTTATATTTTGCTGTTTCCTCAGCAGACATTTCTTCTCCCT GGGCTTTGTGGCTGTTTACATTTCTGTGCTTAATTGATCCATCCTCTCAATATCAGAGAT AAGTTGGAATTAGCACAGGTAGGAGCATTTCTACATGTTTCACAAGTACTTCAATGCAAT GTGTATATCCATGTATTGCAGAAGGAAGAAAATACTTTGAGAACTGAGCAGTTAACATGA ATAAAGGACATTAAATATTATAAACCACATAACATCATAAAAATATAATTAAACAGTTTT TGAGCACTCAGCTACATGGAGTCTGATGCTTCTATGCTTCATATAATTCTGTGCATAAAT TAGGCAACTAGATGTACAGACATACAGAAAACATCAATAACCAGACTCTAGAGCCAGGTC CTATTTGAACCCATAATACAATAATAATAATAATAATAATAATAAAGTGAATTTGGTCCA CCCATAAGAAATAAAAATAGTCAACACTTTAAACTACTCTGACTAAAACACTGAATTTGT AGCTCTCACAAGATGGTGCTACCATTCTTTCTTTAAAGTATGTGCCATTTAGTTGAGTTC TAAAGAAATAATCCTAATAATAATTACACTAGAGATAATACTGGTATAACTACTTTTTTC TATAATAAAAAGAATTTCTGTATATTTTATTTTGTCCTATATTTACTTTTAGTTAACAAT TTTAAGGAATAAGGATAAAAGAATGTCACCAAAATAAAATTTTGACATAGTCTAGAAACA ACAGAAGTTAAGTTAAACGTTCTAAGTACACGATTAAATTCTACACGTTAATGAGCAGTC GCTGCCATGCACTGTGAAAGGAGCTGTGCTCTGCCCTGGGTGGGGTACCGGGCAGGCGCT CACGCCGTGCTTCCCTGTCATCAGATCAGGATGCAAGCTAATGCTAAAGAAAAATCCATC CTGGAAATCTCTTATTCATGATTATATTTAGGATATCCACATATAAAGCTGAATCTTAAT TAACCAGAACAAATCAGTGAAGAACCTCCAGGAACTCTGTTCTCCTCCCTCTTGTCTCCC AGACACGTTAGATAATAGGAAGAAGTGAATTAAAAGAGTGCTTGTGAACATCAGGGAATG TTCTGGGAGCCACAGCCATCTTAGCTACCATGCATTTATACACTTGCAGTCTCATTTATA AAATCAAAAATGCATAATAAGGACGACAACAATGATAACAGCAATCGATGTGCATCTGGG AAGAGCAGCCACCGCGAACTGCTCAGGCACACACATGTGCTCCTCTTACACCGCCCACTG CAATGAGCCAGCTACTCCTATCCCACATCACAGAATTTGAAACTGAGCTTCAGAGATAAC AAGTAATTTGTCCAAGGTCAGGAATGAAGCTTGTCTCCAGGTCATCCAAGACCCTCAACA ACCTCATAAATATGAAATTGTGCTCAACAGACCAAACTGACATTTATCGGAGCATTTTAC TTTTATGAGGCAAATGTTCAAGGGGGATTAATGTGGTGACCTGCCTCACTGGGTTTCCAG ACTGTACAAATAACAGCATCTGATGCTATGGTTCTGGGTAATCCCTGATAACTGAATTGG TTCTAAGCAGTTTCAGGAATATATTTTATGAGGAATAATTAGAGAAATAAATATATTATG AACTAAGAAAGAGAAAGAAGGCGAGATCACACACCTGGTTTGGTCCCTGCCCTCACAATC AGGTGTTGGTCTAATTTTCTCTGAATTGCAGATTCCAAATGAAATGAGGATAAAGCAGAG TGAGAGAGGAGGGTAGAGGAGCAACGTGGGTGGTTTTCAGGTGCAGCTGAAGGGAAGGCC ACCACTGAAGGTCTGAGGGGGCCGGGATCTCACATTTCTCCTTTACTGAGGCTAAGATGT GTGTTGACTGTTCCTTGTGCCCAATTCCTCACCCAATTGACCACAAATGCCTCTGCCTCC TGGGGAGGAGTACAAGAGAGTCAGGAGTTGAGCTGTTGTTGGAGAAACTCCATCCACATG AAAATCACAAGAGTGAGGCCAGCAGATCCAGGAGCCTATCTGCTTTCTCAGATAACAATC CACAAGCCAGTTAGTGCTGTGCCCTGTTAGTTTTTTTCTTTGAAAAACTCCAAATGACTT AAAGTTCCTCTTTAATGTAAATATTAGAGATAATTTTCACAAGGAGAAGTTTAATGCCCA CAAAGAATTCACCAATAAAAGGTGAGTCAAGTAATGATTCCTTCCATGAAGAAAAACCTT CCTGGTTACCGGGAAGCAAACCCCACTGAGTTACTAAAAAGCTAGGCATTCACAGATGCC TTTCCTTCTGCACAGCATATGCCTTTCAGCCTTATACTCATGTACTTAAAAAATCGGAAG GATCTTTGAGGGAATTGGCCATTTCCTTTATAATATTCAAGTTTAGTTGAAGTAGGGGTT ATTTTTCCCAAACAGGAAGCAGAATTAGATCACAGTCAGCATTGGTGACTGGCAGCTGCC CTGAGGCCCATGATTAGAAAGGCTGGTCTGTGGATGTCCCTGTTTCACTTCCAGTCCACT TTCTCATGGAGCCTGCATGAGGCAGACCCTGTGCAGCCAGCACCCCTGGCCTGACTGTTT CAGGAAAAAAATCACAGCCTTGGGAAGGTCACAACTAGGAGAACACAGCCTTTGCTAAGC ACCCTATGAGGCACAAGATAGCCCCTACAACAAAGTGTTATCCAGCCTAAATTGTGTGTA GTGCCCAGGTTGAGAAACCCCATCCCAGACAACTATGGGATGGGTAAGAGGACGGGGAAG AATGCTGACGCTGGAGGGTCCAAGCTTTTGATTATGAAACCATTCCTTCCAGAGTCCCTA GAGGGAAGATCAGAAAATTGGACTGTGCATTTGCAAGCCTTGTCTCTCTCAGAGGCCCAA GAACTACACAGCTGGACCTTCCAAAGGGCAAAGCCAAAAGATGGTGGGAGGAAAGTACAG GTGATGTAGCTGATCATCACACCCAGCAGCCCCTCCGTGGGGCTGAGACAGATTCAGGAG CTCGCACGTGGAGGACTCAGTGTCCTGCTTCATCAGGTTTTCAATTTAAGGCTCGGGCCC TGGGGCCATGTAACTGTGACTTTTCTCTGCAGCGATGGTAAGCAAACATGAGGAAATCCT TGGTAAGAGGTTAATGCCTTCACAGCTGCGTTTAAAAAAATTCCGTAACGTAAAGTGAGT TTTATTTAAAAAGTGGACTGTAAATCTTCCCTTTTAATTTTTTCTTCAAGAACCTCTTTG GAGAATGGGCTAAAGGAATATTAACTCAGTTGTAACTGAGTTACCATTTACCTTGTCCTG TCCTCAAATACAAACACAGAAGCAACGGAGAAACCAACCATGGCAAGTGATGTTCCCTTT GGGTCCCACAGCTGGTAAGTGAAAGTACGGGGGTTCGAACTGGAATCTCTGTCTCCACAG CCCACTTAGAGTTTAATTTCTTATCAGGAAACGTTTTTCCTTGGTGCTGTTTATAGGAAG TTTCTAATAGAGAAAGGAACTCTAGTTCCCAATGTCACATTACCAAGGCATTCTTTGGGG GATCTGTGGCCTCAGCTCTTTTTCAGCCAGCTTCCCTCAGCTCTGTCTCTCTGTAGGGAT CCCCTCCCTTCCCAAGCAAGTGCAGCCAGTCAGCTGACCTTGTCAAGTTTAGGAGCACTT TAACAACCAGATACCTAAGTCTAAGTCTAATCTTGAGTCTTTAAAAGTAAGAGGCTGTGT AAGATAAAAATCTAGGTGTTTACGCTGTCTTGGTGTCAACATTTATACCTTAACCACTTT TGCTTCTACAGGATGTGTATCCAAAGGCCAAACTTTTCATGTCTCTTTAAATCAGCCTGT AATGTGGGTGTGAACTTGATGTCTCTTTAACATGGCCTGTAACATGGGTGTGAACCACAA AGGGTGAAACACATTTTTAAAACCTCTCAGAGCTTTCTCTGCATACCTAAGACCATGGCA CAGCATCTTCTGTAGGTGAGCCCCCGACCATCGCACCTGCTCTCCATACAGGACTCTAGG AGCAGATGCTCAACCCCCTCGGAGGAGAAACATCTGGGAAAAACACTGGAGTGGGCTCCC AGAAGGGGAGGCCAGGGTGAAAAGAAAGGTCACCAACCCTAAATCCATCAGGAACATGCT GACCTCTCTTCAGGGGATGCTGCTTAAGAGACCTTTTCAACATATTTTTATCTGCATGAT ATAAATTTTTAAAATATGCTTGAGTACCTAATTTTTGGTATTTTATTTACATGAAATGTT TAATTCTCCGACAGTTTTATATCCAGCAGCATATAGCTTTGTGACTCCAATGACGAAAGT ATTCAATGTGAAAAAATAAACAGGCTATTTTATGATTGTTTAACTTTGCCCTCAATTTGT GTACCACTCACATTTGCAAATAATTGCTCAATTCTCTTCAGGGAAACCTCTGAAGAATAT TTAAGTAAGACAGATTGAAGGACCATTTTTACTATGGTAAATCTTAACAAGTTTTATAAA GTAGTTTCCAGTAATAACAAAACATTTGAATGTGAAAAATAAAATTCTTAGAAATATAAA ATTTATGGTGCTAAAACACAGAGAAAATGGAATAAGGATGAAATTGTAATTCAGAATTAG CAAACTTTCTCATTTTATCTCCATTGTAAATTCAAAAGCTTCCAGACAGCAAATGTGGAG GAGATCACATGCTCCTCAGATGATGCCATGGCTCCCGGGGCTCAGCAGCCCTGTCCCCAG CACACACTCCCTACACAGATAACACTGACGGTTAGCTCCTATCCGGGGCTTAGCAGCGCT GTCCCCAGCACACACTCCCTACACAGACAACACTGACTGTCAGCTTCCTATCACCCTCAT TACCTTAAAGGCAAGTAAGATAACAAAAGCATAGCATTTTCTAAATGAAGTACTTCTCAA AAGAATGTGAATATTCTATAAATTAAAGGGCTGAACACTTCCCAGAGATTTTCATAACCT GTCAGATTAATTAGGAAGTTTGTGATCACAAAATGAATATGAATCATTTATAACATATAG ATTTACTGATTTACCAACTCTCTCATGATAGCTGGAAAGTCCAGGATAGAGCTTATATTC ATTTCTGTTACCTGCCAAAAAAGAGGAGAGTGGTGATTTTGAAAACTGATTAGTATATAT CATACAAAATACACAAAATTGCCAGATCCTGCCCTTGCTGAGCAAATATTTTAAATCACT AAGTTGATAGGATCATCATCATTTGATTGCGCTTTAAATCACAAGGTATACCTGAATAAA GCCAGAAGATACATGAAGTATAAGGTAGATGATAAATACCTGACATCTGTATGACACAGA AGTACACACACTATTCTCATTATAAATTCAGATGACAATTCTATTAGGTTCTTCTTCAAT TGCATTGAAGGCAAAGAAACAGAAATCACTGATTCATGGAAGGATTTACACTGCATAAGA GCCATTCACTAACTGCATCCACATTTCACACTGGATTCCCGTTCTGACGCTCTGGGGTGA TGTAGTGTAGAAAGAGGCAGAACGGTCTGGGGGTTTGCTTTTCTTCTTCAACTGCAGAAA AACTGATTCTAACAGTACAGAAGACGAAGAGCACACCTTGCACATCATGTTCAGCTTTAA AAAGAACTTATCCAGGAGCTGGAGATCTGGAGATGGTGTCTCTTAAGTGGCCTGTGCCCA CACCCCCTTTTGCAGTCTCTGCGTACTCCTAAAGACAGGCACACACCAGTGTGAAGGCCA CTGGCCTAAGACATTTATGAAAGTCAGAATTTAGAAATAAAGTTTGGTGGGATGGGAAAA GGATACAAATATCCTCTGAGAATCTATTTTTAAAAACTGACTAGAAATAGTTTTGAGCAA GTGACGAGATATAAGACAAACAAAATATATGCAAATTAAGATTTCCTTCACTGTGAAAAT TGGTACTTAAGTAGAAATAGAAAAGTGCATTCCATTCACCTTAGCAGATCAAAATCTCAA AGTACTTGGGAACAAATTTAACACAAAAGGCACAGAAATTACAAAGTCTTATTGAAAGAC ATAAAATCTCAACAAATGGAAAGCATGAAATGGTAAAATTATTATATCTCAAAGTAATAA ATGTATACATGTAATGTTACCATAATTAGCATTGAAAAATTATAGAATGGATACAAGTAC ATCATACTGTTTCAACTAGAATTGTATATTGGGGAGGAGGGGAAAATTAGGAAAATGAGC TCAAATTATGTGAAGACTAAGTATCCAGTAAATGCAAAGATAAAAAAATCACAAGAAAAT CTAGGAGACTATGAACATACTCTTGTGTAGGAGGTGGGAAGACCTTAATCATGACCAAAG TATCCAAATCTATAAAAACTAAATGATAGACTTATTTTTAGATAAAATTTAAAACTTTCA TGGAGTAAAATTATGAAAAACAAGATCAAAAGAAAAATGGTAAGTGTAGAAATATGCTGC AATCCAAATGACCAACAAAACCTATAATATAGATAACATTTCCATAAATTGAGAAAGCAA CAAATATCCCAATAGGAAAAATAGACCAATGAAATGAAGAGACTTTTCAGATAAGATTAA ATCCAAAACACCAGCAATTTATATGAAGAGATGTTTACATTCACTAATAGGAATAAATAC AATCCAATTAACAAGGAGATGTGACAAGCCTTGACTGGCAAAATCTTCTAGATGCTTCCG CACTAATAGTGGTGGGGAAGGTATATGCTGAAGAATGTCATAATGGATGTAATAGTTGAA AATGCACTTGGTGGGGAATGTAGATGGTGGAGAATGTATATAGTGAGGAATGCATACAGT GGGGAAGATATATGGTTGAGAATGAAAATGGACAGTGGGGAATGTGTATAGTGGGAATGT CTGGTGGGAAGCCTATATAATGAAGACTTGGGAATGTTATTGGGGAGTGTATATATGGTG GGGAGTGTATATATGGTGGGGAGTGTACATATACTGGGGAGAATACATATACTGGGGAGT ATATATGGTTAGGATTGCACATGGTCGGTAGTATACACGGTACAGAATATGGTGGGCAGC ATAAATGGTGGATAATTCATATGGTGGAGAATGCATATGGTGGATAGTAACCATGGTGAA AAATGCACATGGTGGGTGGTACACATGTTGGGGAATGCATATGGTGGGTAGCATACATGA TGGAGAATGCATATGGTGTCTAGTGGGAAATGTGCATGGTAGGAAATGCCTATGGCGGGA AGCAACTATAGTGGGGACTATTATGGTGGGAAGGTTATGGGGAGTGTATATATGGTGGGG AGTATATATGGTTAGGATTGTACATGGTGGATGGTATACATGGTGGGGAATGCATGTGCT GGTGAATGTTACGGTGGGGAAATGGTTGATGAGACTCTAAGTAGTAAAAACTTTTGAAAA GTAATCTGCTAAATCTGTTAAAACTTTAAAAATATATTATTTGACCTATTATGTCCACTC CTGGTAACTATCTCAAAAAAAATAAAAGTGCCAGTATATATAAATATTAATTTAGAAGTA TATCAATTGTGACACTGTTTGGCATGGAAAAAAATCTGAAATAAAGTTAATATACATCAA TAGGAGAGTGAATGAGTAAACTATATACATTTGTGCCATGGATACTGAATAATTATTAAA AAGAAGCAAACAGAACTATACCAGTTGACTTAGGGATTTCTACGCGGAGTTGTTGAGCAA AACAAACCAACAAATAACAAATAAATAAATAAATATAAAGAAGATATAGTAAAGCACGTA TAAGATGATAGCATTTTTATGAGACAAAAATATTCTGGCCATGTTTATGTATATGTTTGT ACATGCCATGTGTAGGACTACACAAGAATGGAGAAAACAACGTGAAAGTTCATAATTTAT GTTGTGAACGTGGGTTTCCTGAAATCAGGGTAGAGGAAGGTATCTTGAAAGTGAAAACAT AGGTGAAATGGGAAAAGGAAGCAACACAACAAAGGAAAAGAAAAAAAATACTGCCTTCAC AGACCCTCCATATGAGCATACGTGCATTTCCATAAAATTATGTGTGTGTGTGTGTGTGTG TAAGGATATGTAAATAAATTGAAAATACTTAGTTTTTAAATAAAGAACTTAAGAAAAGGT CAGATTTAACATAAAACATTAAAAGTAGTCACTAGTTTTAAATTTTTAGTTTACTGAATT AAAAACTGATATTCAAAACTTGAGAGATACAGCACATGAGAAATGATGGTATCGCATGGA AAAACTGTAGTGGCCTAGCCACAAAGGATGAAGCTGAAAAGGTGGAGGGAGGAGGAGTGT TCACGAGTGTGTCGAGTGAGGCTGAGGCTGCAGAAATGTGGCCAGGCTAACCTGTCCACC GGCAGGGACACAGCTGTGGCTGTGCAAAATGGGGAGGGCACTGCCCATCTCCCCAAGAAA GGGTTCGGGGAACACACGTGGTCACCGTGGGAAACAGATCCGCAAGCTGGCACAGGCAAA GGGCCTGTTTTTAGAAAGCTCACACAAGGGGGTTATATGGCAGAAACAACCTTCAGAGCT TTTCAATTATTAACGGAAAGGAATTTTTTGAGGTAAGGTCCACAGTCATTTTTAAATCCG CACTGATAAGGACCTGATACTAAGAGGACTAGAATTTTTATAAATGAGAGGATTTCATAC ATGCATATGCAGGTATCCATTCTCAGTGAGGACATTTTATATATTTTAAAACATACATAT GGGTCAAATTCTATATAATCACTCAGATCTAAAATAAAAATAAATTCAGTGCTCATATCT CATTAGTCACTGCAAATATGAGTTTCAGTAAATCAATCATCTGAACATGAATCAGCAGTG GACCACGGCTTATCCCAGAAGAACAGGAGACAGACGCAGGGGCAGGAGGCAGGTTGGTAA TGAGGAATAGGCCTGGTTCCTGAGCATCTTCCTGGGAGGGTTACATTTAGACCAGTCAAA GGCACAGCCAAGAATCATATGAGGGACTTGGGCTCAAAACTGGGGAAAATGATTACAGAA AATTAAGGAGGAGGCCGAGGATGCGCTTCCCGCCTTCTGCAGAGCTTTACTATTTACTCC CCGCAAAACTTATATGCCTTCTCCCACTAACAGCAGTTATGTTTCTACATGTAATCTCTC TCCTCTTGTTCTGAAAGTCCTCTAAAGGCAAGATCTACGTTAAAGTCACCTTTGTGCACC CAAAGCCACAGCACAATGACTCTTGTATAACAGTCAATCATCACATGAAAGTCCCTACTT CAATGTATTCCTATTTACTGGTAACCTCCATATACGAAAAACAGAAACACAAGTGATTCA CAAAAATGAATGATAGAGAGAAAGATAAAGACCAAAACCTGGTGCTTTATAAATGTCATC TAGTTTAAAAACCACCTTATGAGATCCTGAGCTCCAAAGAACATATGTCAAAACTGATAT TCAGAATTATAAATATGAGTATGATAAGAAAAAAACAGGCTTATTTTGTTCTCATTTCAA ATCAGAAGGATAACGGTTTTTGGAAGAAATGGCACAGAAAATAAATGAGAAAACCTTTGA AGATAAATATCTTTGTAGATTTAAGAAAGTGTCTTATGGGCCGGGCACGGTGGCTCACGC CTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAGGAGATCGAGA CCATCCCGGCTAAAACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGC GTAGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGA ACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAGCCTGGGCGA CAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAGAAAGTGTCTTATGAATAGA AAGAGAAGTTTTCATAAATTATAGCAATGACAATTTGTCTCATGTATTTAGAAGAGGCTG AGCACTTATTTTACTCTTAAATATGTTAGTTCTTCTATTTAACTCTAAAGTTTAACAATG TATCTTGATTTCTTAATGATAACATTTAATAATTACTTAATTACAACTGTATTTGAATTG CAACAAAAATATTTACTTTGAGAGCCAGAGTTCAGCTGGACTGGTGCAGATGACTGCTGT GGTCTTGACAATGGCTTTGGAGGTAATTCTTTAGCCTGGGAGAAACAAAAAGATAAATAC ACATAATTTTAAAATCTTGTTTTTACTTAGGCACATATAACTCTTTTCTAATGAGGTTAT GTAGCAAACTTTTATCATGTGTGCTTATTAATGTGGCACTCTCAAAGCTCACATGCACCC CTCTGGACTCTATGTAATTGAACTGGATGACAAGACTCAGATGTGGACAGGGTGTGCTCT TCTCATGCCTGGAAGCTAACCTCCCCCAGGCACCTCTGACCACCTGTGCAAGGTCTTAGG GAGCTGCAGGGACGGTGGTGTAGTAATTGGTTTAGCAAGCAACTGGCAGAGGCAGTGACA GACAAACTCTAGGCTTCAGTTTTTATTCCATGAAACAGGCATCATACCAACTCTGAAAGG TGCTGTGGAACATCATGAACAATGCACACAAATCCCTCGGTGCCCCAAGGCCTGACATAC AAAGGCGTCAGTATCTGCAACTATTATTCATATATTATTATTGAGATAAGGTCTTACTCT GTTGCCTAGGCTGAGTGCAATGGCATGATCTTGGCTCAGTGCAACCTCATGGGCTCAAGC GATCCTCCTGTTTCAGCCTCCTGAGTAGCTGAGATTATGGGCACACGCCACCATGCCCAG CTAATGTTTCTATTTTTATGGTAGAGAGGGGGTTTTGCCATGTTGGCCAGGCTGGTCTGA AACTCCTGATCTCAAGTGCTCCACCTGCCTCAGCCTCCCACATATTATTTGTATTATTGA TACAACAAAGTTCCATCCTTGGAGAAATGCAATCACAGAGGACAAATTATGTTTTTCCCT GAAATCTGTACAGAGGAAATGTCAAGGTAGCATGACCTTTTCACAAGAATGTGAAGTCAG TGAAACTACGAAGGAGGCTTAGTAGGTTCTTAGGAACCTGATATCAGGGACAGAATGTTC TACAGAAAGAGATTTTCTGAGAATACTGAGTGAAACATAAAACCAAACGGTACAGAAGAC TTCCTCTGCTCCCTTGCTGCTTTTCTTGCATTGATTCGTTGTCCTTCATTTTCATACTTT TCAGTAAAGGAATCAAGAATTTCATAAAGATCTTCGGCTTGAGCAGGCCGCGGTGTATCT CCAAATAAAATGTCATAAGCTCGGATATCTTGACAATAAAATCTAATGGGAAATATAAAA TTAAAAACATTTTAATATACACAAATCTTTTCTAGAGTTAAACATAGCATGTGCGCACAC ACGGTGTGTATATATAATCATTCATACATAGCACTTCATATACACTACTTTTTAAACACT AACTTTAAGCAATATCCCATGTTCAAGTCTTAAATGTACCCCAAAGTTCACTTCTACAGG CAACTACCATAAATATCCTTATATGTATCCTTTCTTTATTAATATAAAAAGCACATCCAC ATTATCATGGAAATACTTATACTTGCCCATATATATACATACACATATTCATATATAAAC ACATATAAATATACACACAAGCACATACATTTTTATAGGTTTTTACTTTTTAAATTTCTT TAAAAAATGGTACCTATAACTGTGGCTTTGTAATTTCCTTAAAATATTTATTTTTATCAA GATTAAATAAACATTTGCCTTACATGCTTGGAGGTCCTGCCATTCATTAAGCAACATATT TGTTTTAGTTTATCCAGGGTTTAGTTGAACTTTAGTGGGAAGGCCTGCCAACGGGCTCGA ACCAGAAGTTTCTAAAAGCATTCTTTTGTTAACTGTTCTCAAATTAATAAAGCCAGGAGT TAACACATCACTTTTGATTTTATAAGATGAATAGTTCTGAAAACCTTATTTTTCCCCATC CCTCCTATTTTCTACCTCTTGTGGTTTATATTTAGCTTTATTAAATAGTGCTGTTCAGTT CCTGAATGACTCGGTGGGGTAAACACTGGATGCTTTGTCTCGGATAGTGGCGGGTCTGTC TGCCACGCGTGGCGAATTTGAATGGCCAATGCCAGCAGTGCCAGCCGATCAAGCTGGCAA TGATGGAACTTCTGCAGGTTCTGGAAGAAGTCCTGCTGTCAGTCTTAGCTCTTTATCTCT TTCTGGGCCTTTACACATATTTTAGTGGCAATTTGTAAGAGCCACTTAATTTGCATCTTT GGGAAAAATCAGCCAGATGCCAATTTAAAGTAGAAGTTTCCCTTTACCTTTTAGGATACT TCCAGATTCTTTTTTTTTTTTTAAATCAAACTGTATTTTAAATTGCTCTCTATTTGACAT GAGAAAAGACAAAGGTGGAGTGTAGAACAGGAAACCTCACAACAAGGAATACTGACTGAC ACATGAGTTGTAACTGGTGTGCCTTCCACAAACATCTGAAAATCACTGAAATCGGTGCAT CCAACTAAGAGTATTACTAACTTATGTTTAAGTTTCTTTTTTTTTTAATATACTTTAAGT TCTGGGGTACATGTGCACAATGTGCAGGTTTGTTGCATAGGTATACATATGCCATGTTGG TGTGCTGCACCCATCAACTCGTCATCTACATTAGGTATTTCTCCTAATATTATCCTTCCC CCAGCCCCCAACCCCCTGAAAGGCCCCAGTGTGTGATGTTCCCCTCCCTGTGTCCAAGTG TTCTCATTGTTCAATTCCCACCTGTGAATGAGAACATGTGGTGTTTGGTTTTCTGTCCTT GTGATAGTTTGCTGAGAATGATGGTTTCCAGCTATCTTAAAATGCGAAGTGGAAAAAACA GCATTTACAACTGAATATATATGGTGATTATCATCATATATGGCAAAACAAAAAAAATTA TGCTTAGGAAAATGTTGGAAGGCAGTAAAGCAAAATGTGAATTGTGTTAGTCTTTTAAAG GGATCGAGTTTTTTTTATTTCTTTTTCATGTGTCTTCTGCATTTTCTACGAGCATATATT ATTTGTATATTTAATTTTTAAATGTAAGATACACACTTAAAACCACATGTTGTAAAAAGA ATATATAAATGTACTCTGCAAATTATATCAACTTTTGAAGTACTATTTTCTCATCACACT TTCAATTAAAATCACTTTAACTTGAACTGACTTTCTATTAGTTTCTTTCCTTTCAATCAA ACAGCTCCCTTCTAAAGACACGCCTGCAAAGAGTCCCCTTGACTTGCAGTACGTGAAGAC GGCAGCGGAGCTTCTCAGGGCCACGTTTCCTTCCAAGTTCCTGCAAAGCACAAGATTTTG CATCACAAAGCTGTGAGCAGCTCCAAGCCGAGGATCACTATTTAAATAGCACTCCTTCTA GCTCAAATGAATTATTTTGTTCTGTACCTTCTTCAGCTGTTTCTATGTTTTACTTACTGT AGGCCTAAATTAGATGTTTTAATGTGGCCTAGAGGAAAAACAGGCCGGGGGAAGAACATA CATGAAATTATTACAGAAGGCTCTGGTAACATAGAACTGTGTTGAAAAAGAATACAGTGC AGCATGTGTAAATATATTTTAAAAATTTGTAAATCTGACATTTTCCAACCGGATCTTCCT CTCTTAAAACTGGGAAATACATCTCAAGAGTGCTAAAGAATTTGGATTATTTTTGCATTG AGTATTTTCATGGAACCAAGAAACATTTTTAGATGATTTTACTGTGTAACTTCTATAAAT AGTGTGGGTATAAAATATCTCTACATTGCACAATTAATCCAAGACTAGCATTTCATTAAT AGAGAAGAAAAATACACTTTAAGTACTGTAAACACGGCTCAAAAAAAACACATCCATATC CAATTTTTATGATTTACTTTGAAAAAAGCTCTTTCTTTCCTAATCGAAGCTTAACTTTAT CATAAAATCTGACTTGTGTTTGGCTCTCTCAAAGCTTAAGGTGGATTTTATGTTCAAGTC TGACAGATACAATGGCCTATGCTTCCAAAACATTTCATTATTTCTTGTGTGTTCTGGTTT CAGATTTTCTAGCTTATCTCACTGGCTGTGTTTTGTGAATTTCCTATTTGTGATGACCTC AAATCTTTCGGGCATGTATAAATCTGGGGATGTACAAATCTGTTCATTTTAATTCAAGTT TCCTATTAATGCAAAATAAAATATGCAGTTGTTAAACCTTTACTGTCTAACATCTATTTA AAGAACTCACCTTCCCAAGGGCCCAACCGCCACAGTCAAGTTCCCTCCGAGGGTCAGATT TCCGCCTTTTGCAAAAGCTTCTACAGCACGGTCATAATTCAGAATTATCACCAAGTCTGA TACCTAAAGTGTAGAAACCCATGGATTTAAAAATCGTTAAGACTAAATATCATTTAAAAT TCATCTTGACTAACACTCAACTACACCATATGCACTGTAGCAAAACATCAATAGAGACAG GAAAGAACGTGAGACAAGAGCCATATTTTTATTTTGAGCTGATGAATTATGAAGCCAATA TTGCCACAGGTAATTACAACAAACCTCAGCGAGCATTTACTGTGCACCATGTGTATACTA TGAGGTTTACCTGCATCATGTCCTTCAATCTTCCACACAACCTGGTCATGTAGGTGGTGA TCCTAAGGTTTAGTGGGGTTAGGTAAACCGTCAGTGCTAACAAGTCAAACAAAGGTTGTT GGAAGGGATCCAACATGCTCTCTGATCTCATCAGACTAAACTTTGTAAAAGCCAAGCCCG AAGAGCACAGCACCAGGGACGATGGTGCTGAAGGTCCTGAGAGCCTTTCTACACTCTCCT CCTGGCCAGGGGTGTGCTCCTTACCAGGAAGCTGTGAACCTGGGCCACTTCACTATAGGT CACAGAAGCTCAACACACCAGAAAGCAAAGCAGTTTCCATTAGGAATGCCTATTTCCATG ACTTAATTTTTCTTTTTTTTTCCTTGAGAAAGAGTTTCACTCTTGTTGCCTAGGCTGGAG TGCAGTGGCGTGATCTGAGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCCT GTCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGTCACCATGTCCGGCTAATTTTTTG TATTTTTAGTAGAGATGGGGTTTCGCCATGTTGGCCAGGCTAGTTTTGAACTCCTGACCT CAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGATTACAGGCGTGAGCCACTGAGC CCAGCTGACTTAATTTTTCTCTAAATAAAAGAAGAAACTACAATGAGATTCAACTGAATG CTCAAGGCAGGTCAACACAGTGAAAGCATTTGTTACTCAAATTAATCACTGCAATGTGGA AGTCCAAAGTTAGAACTGAAAAATAATATGACCCATCAAATGAGAGGCAGCATGGGTCAG GGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCATGGGCCAGGGGAGGCAGCATGGGCCAG GGGAGGCAGCATGGGTCAGGGGAGGCAGCATGGGCCAGGGGAGGCAACAGCATGGGCCAG GGGAGGCAGCAGCACGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAG GGGAGGCAGCATGGGCCAGGGGAGGCAACAGCATGGGCCAGGGGAGGCAGCAGCACGGGC CAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGC CAGGGGAGGCAGCAGCACGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCATG GGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGTCAGGGGAGGCAGCAGC ATGGGTCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATG GGCCAGGGGAGGCAGCAGCACGGGCCAGGGGAGGCAGCAGCATGGGTCAGGGGAGGCAGC AGCATGGGTCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCACGGGCCAGGGGAGGC AGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGTCAGGGGAGGCAGCATGGGCCAGGGGA GGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGCCAGGGGA GGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGCCAGGGGA GGCAGCAGCATGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCACGGGCCAGG GGAGGCAGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGCCAGGGGAGGCAGCAGCATGG GCCAGGGGAGGCAGCATGGGCCAGGGCACCCCTGGGTGTGAAGAACCAATGTCCATCCCA GCTCCGCTTCTCGAGAGCTGTGGACTTTGGGGTCTTTTAACCAGTCTTTGTGTCTCTGAC TGTTCTGTGTTTAAAATTTGCTTACTAGGACCTACACCTCATGGAACTACTGTGAGAATC AGATATAGGCGTCAAGTGTACCTGGGAAGTTGAAACAGTGCTGGCATGGGGCTAAGAATT TGGGCTCAAAATTAAAAATAGTTAGGTGGGAACTCCATTACTCCCTTTTGCATGCTGTGC GACCTTGGGCAAATCACTGAGCTGCTGAAAGCTGCAATTTCCTTCTCTGGAAAATGGGTG TAATAATAGTGGCACACATTCAAGGCTGTTTACGGATGAATTGAAATCAGTTCAATAAAA CATGCAAAGGTCAAGCAGACTCGTGCTTAAAATATGCCTTCATTATACAGTTATTCACAT TTTTTAATCAAATCAATGCTCTCAAGTCAACATTTTTATATGAGTGACAGAAAAATCCTG TTATAACCAAATGAGATTATACTTGAAAGGCCCTAAGAGAGTTCCTGATGCAAGTATGTT CTTAATAATGTTCAATTTGAATCATTTTATGAAATAAAATACACTTCAGATCTGTAGGTC AAACTAAATCTACCAGAGAGCTGACCCACACAAGATGCTTCAGCTTGACGCTTGCCAACT GTTCATTTTATTTTACATATAGACAATTTCTGAGGGTTATGGTGCTGAATGGCAGATAAT TATTTAGCTTTTCTTATGCAAAGTTAAGCATTTTCACCAGTGATTGTATAACCTGTATCT TGTATGTATTTTTAGATAACAAATTTGCCTTCCATAATGCTTCCCACATTTCCCACTCGG AAAATACAAAGTACTACCCATGACCTTGTAGCTACACTGGTTCTTATGTTCCGCTTCTGC TTGGTACATCGTGGTACAGTTAAGTAAGGCCAAGCTATGAGAGGCAGCTGAAGGAAAAAC AAAGTCTTTTGATTTTTTTTGGTCTGATCTCTCTTTAGTTCTTTTGAAATAAGAATAAGA GAATATTGTGTTTTTTGGTGACACTACCAATTAGCCCGAGAACCAGGTCAAAAGCTCTGC AGACAGCTTGGCGAGCATGTGAGCAGCAATGGCCCTCAGTTTATTTCCACAGCTTAGAAG AAGGAGCAAGACAGATTTCCTGCAGGAATCTGGAGGAGCTGAACAACACATTGGGACGGC ACTCTCAGAAAACCCTGTAAGCATTTGATAAGACTTCTTTAGAAGTCTGCATTAAAACTC AACTACATAACAGTCTGATCGAAGAAATAAGACTTGTGTTTTATTTATAAGATCAGTAGG GTGAGTATGGTTCACAATAATCTATTGACTATTTCAAAATAGCTAGAAGAGAACTTGAAT GCTTCCAGCCTAAAGAAATGACAAATATTTAAGGTGACAGATACCCCAATCAGACTGATT TGATCTTTACAAATTGTATGCATGTATTAAATTATTACAAGTACCAGGAAAATATGTAGT CCACTATAAATCAAAAAAAAAATTAAAAAATAAAACTGAATAACTCAGATGCAAGTGTTT CAATTAAATAAATTCTTAAACATTAGAATGTGAAAAACCACAGCTGCCATGCAGGGGAAG CTGCGGGAGAGAAATGTCCCTCTTCTCTGCGACTGAATTTCCTGAAAGCAGCTGCTGAGA GGGTACCACCCCATCTCCCTCTTGTGTGGTCAGCCTGCTTCACACCCACACAGCTGAGTC CCGGGCTGTTGTCCTGTCAGAGCATCACCCCCTTCTGGATGATTGACTGCTGTCAGCCTT CAAGCCCCACATCTGGACAACCCGCTAAGAAAGCTGGGCTTCCTCCTCCACCCTGCCGTT CTCTCACGCCACTCTTGGGCTGGCCTTGGAGCCTGCCCCAATCTCCCTAAAAGCCTCACT ACATGGGGAATAAACCTTTTCCTCCCTCCTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGGCATGGCCAGTCTCAATATGTAAACCAAGCTTAAGTGGAGCGTCCT TCCAGCAACAACACCCCCTCCATTCCTCAGACCAACAGATCTTTTCCTTACATCCCATTC TTAGGGGGCTTAGAAACTGGACTCTGATCTCTAACAATAATTTATCCTCAACTTAAACCC AAATACCTTCCTCTTCAGTAAAGTGAAAGGGCCCATGTAAATTCTCCCTGGAAAAAGCAG TCGTTTTTGTTTTTTCAAATTCCAATCTTGAGTAAAAGCCAGACTGCTCTGGCTTGATGA CCCAGTGTGAGCTCTAGCTCTGGAAACACAGCAAAGGACTGTACATGTCCAAAGCCAAGC CAGCAGCAGGACTTTCTGAGCTTTGGGCTTTGCTACAACTGTCATCCAAAAAGAAACCGT TAGTGGTATTTAAAGCAAATGTAGCATTGTCTTTCCTCAGACCACTGACTTTCACGACTT CACTTCTCACAATCTCAACTCTCTTTACTAATCTCTCTCTCTTTACCACAAAAACTTCCC CCTCCCCCAAATTAATCCCTAATCCAGATACACGTATTCAGTCACTAATTTAGACAATTA TTCAGTACCTCTGATGTTCCAAGAACCAGGGAACTCTCCACCCTGTAGAATCTGGGAGTC TAAAGGTTGAGATTGTCGAACATAAATTAACCCCACGCCGGCCTTCTGGCTAAGCTTAGG GTCACTTACACTTATGCCCCTGGAAGAATGAGTCTGACATTCACTCTCCAGTGAAACCAC AGCACGATGCAATAAGCTATCCAGGAGCAGCCTCAGACAGCAGTGGCTGTTAAGCAGCAT CCTTTGCACAACTAGACCTTGTTAGTTAAGAGAACTGACCTTAAGAACAGGCCATTAATG AACACACAATTAAGACTGCAATCTTTTTCCACCAGGATTCTCTAGGAGAATTAAGCACGA ATGTCCTAAGGCATCCATTGCAACTAATAGGTTAGCATCTCCCCAGATATTCTAGAATAA TAGTACAAATAATTAAGAAGGTGGTACTCCAATCCCTTTCTGTGTTTGGAAGGTCAGATG AAGAACCTGGAGCAAATGTAACATTTTTGCAGCACTGGATACACCACGTGGAAGGTACGG GAGATGTCCGGAGAAAAACTGAGACTGACCCAGGCAAAAAACAATGCGCCACAACTTTAG CCCAGAACAGGCAAGCTTTGTTGCCAGTCACAAATATCAGAAGTGAAAGGGGGTATTTAA GGACCATTTTATTCAACTTAAAAATTTTTTATTTTACAGATTTGATTCAGGAAGATTAAG TACTTTGTTCACTGTTCTATAACTAACAAAAGAAGAGCTAAAACTTAACAATTACAGTTG AATCTCCATCCCACTGTAGAATGTATCTACAAATCAGAATGACACTGCAGTGGTGGCATA AAGAGGCCACAGACCCTCTCCACAGCAAAATAACCGTAACTGGTAAAAATTATTTTAAAA ATTAACACTTCTGGAAATTGTCCTAAGGGCATATGGCAAGTGAAGAAAATGAAGACACAT TGATTCAATGAACACTATTAAATATTGGTAAGGAAGAGAGAGTTGGTGACATTTGAGCTA TAACCTGTGCCCCGCTGCAGGTCAGCCTGATGGAAGCTCCTCTTGGGGAAGGGGGTTTGC AAGAACACAGACTTCCTTCCCCCAGCCCCTGGTCAGGGCTGCAGTATATCCACAGGAGAG GCTTCTGCCAGCATTTCTCTTCCCACAGCTCCTTGTACAGAAGCTCCATTCCAGGCAAGA GCAGCTGAGAGGTCTGGAGCTTCCTTCCTCCACCCAGAACCCATGTGTAAGTGAAGGCTC CAGCCTAGCACAACAGTCCAGGAGCACCAGGACCCCACTCACTCTTGCCCCAGTTCACCT GTGGGGCAAAAGCTCCACCCTGACAGAGGCAAGCCAAGCTACTACACCACCCAAGGCTGC AGGGATGTCACTCCAAGAGAAGGGAGCCACTGCCCCAGCCTCCAGCTCTGGAGCAACGGC ACAGAGATCTTGGGCAGACAGAGAGACAGGCTGCAAGAGCAGAGAGCTCCAAAGCTCTCC CCAAGGGAAGTGAAAGCTTTTGGAACACAGGGTGGGGAAGTTCAAAGGTGCTGTCAAAAA TGATGCTTTTGGTGATAAACAGGTAAGATGAGGTATTTAGCTCCATGACAGCAACAAGCT AAACCATTGGTGGTCTAGAAAATTATCAGGGAGAACCAGGGACAGAGATAGCTAAGAAGA GCCCTCCTGAAATAGAAATGAGCCTCAAAGACTACCTGTGCACAGGAGCACAATTTTAAC TGGATCAAACTGTGGAGCAATTTATGTCCCCAGGGCATTGTTGGAAACAATGGAGCAATC AGCAGGCAATTAGTGGAGGCTAACAACAGTGTGTAATACCAATGGAGACAAACAGCTTAA CAGACAGGTCACGGACAGGGACAGTCAGAACACCTGTCATCTCAGGAAAACTATATGCAT GCCCATAGACAACATTGGAGGCTTCACAGTAGTGGGGCACAGAATTCATTCAAACAGTCC AGCCATATCTCTAAACAAACAGCAAGCAAACAATAAGAGGCTCCTAGGGGGAGAGGTTGA GCACCCAGAGTTGATACAATATAATATCTAAAATTTCTGATTCTCAACCAAAAATAATAA GACAAAGAAGTGGGAGAGTGTGACCCATACATAGAAAAAAAATTTAAAAAGGAAGCAGAC GAGAATGACTGCTGTTCAGATGGTCCAGCTATCAGATTTAGCAGACAAAGACTTTAAAAC AGCTGTCATAAATATGTTCAAAGAATTAAAGAAAACTATGGTTAAGAAGTAGAAAAACGT ACAATGAGAATATCTTATTGAATAGAGAATATTGATAAAAACATAAAATTATATAAAAGA ACCAAATGGAAATTCTGGAGGTAAAAAGTACATTAAGCAACATGAACAATTTACTAGAGA AGTTTAACGGTAGATCTGAGCACGCAAAATAAAGAACTGGTAAATTTGAATAATAGAAAG TCTTAAAAACTAAGAGAAAGAGAATGAAGAAAAATTGACAGAAACACAAGAAACCTGGGA CACCATTAGGTGCACCAACATATGTGTGATGTAAGTACTAGAAGGCAAGGAAAAAGAGAA AGAAGCAGAAAATTTTCTCAAAGAAATAATGGCTGAAAATTCTCAATCTGATGAAAAACA TGGATCTACACTCAAGAAGCTCAACAAATTCTGAGTAGAATAAATGTAAAAAGATAACAC TCTGGATAGATAATTGTAAAAAATCTTAAAATGCAAGAGAAAATCTGGAAAGGAGCAAGA GAAAAATGACTCATCACATAAAAGGAACCCCAATTAGAATAATAGATAGATTTCTCTTCA AAAACAGTAGACTTCAGAAAACAGTAGGATGACAAAATGCTGAAAGAAAGAACTGGTCAA CTTAGAATCTTATAATCAGCAAAAGTATATTTCAAAAATGAAGGGGATATGAAGACATTC CCAGATTAAAAATTTTTTTTTAAGTTGAGAGAATTTGTTGCTAGTAGAACCATTTTACAA GAAATATTATAAATTCTAAACAAAGTCCTTCAGGCTGAAAGCAAGTGACTCTAGAGAGTA ATTTAAATCCACACTTTAAAAAATCACCAGTAAAGATAATTATCTAACCATAAATAATAG TATAAATGCATAGTTCTTCTCTTTTCTCTTAATTGGTTTAAAAATAAATTTTTTCTATAT TTTAAGTCTGTAACTATAGAAATATTATATACTAGACAATAACCGTACAAAAGAGTCAGG TGGGAGCAAAGTTGTCTTGGAGTAAGGAAATGACACCAGATGGTAACCTGAATGAACAGA AACAATGGAACAGAACAAAAAATGGGAAATAAAAAAGGTTAATATAGCAAGTTCAATGAG TAAATACTTGCTCTCAATTATTCTCTGAGTTTCTCTAAAAGACATAAAATTATATACATT ATTAACTATAATCATGAATTGCTGAGTGTGTATCATATATAGATTTAATATGTATAACAG TAATAGCACAAAAAAGGAGAAAAAAAACTAGAACCATATGAGAGTAATGTTTTTGTATCT TATTAAATCAAGTTCCCATAAATTAGAAATAGTTAAGACATATTGTAAGCTCTGGAACAA CCATTAAGAAAATGACTCAAAAATAGAGTTAAAAAATCATAAAAGGAATCAAAATGCCAT AGTACAAAATGTTCACTTAATTGAAAACAGTAAAGTGGAAACAGAGGGACAAAAACGGCA TGAGATATAGAAAAAAGTAAAATGGCTGATATAAATCCAATGATATCAATAATCTATTAA ATGTGAATGAATTAAACAACCAAATAAAAAGGCAGAGATTATTAGCATGGATAAAACAAC AATAACAACAACAACAACAACATCCAATTATATGCTCCATAGGAGACACGCTTTAGATTC AAAGTTACCATTAGATTGACAGTAAAAGGATGGAGAAAGATGTGTCATGCAGATGGCAAC CTAAGAAAGCTGGAGTGGCACTCTTTATATCAAACAACAAAAAATGTAATTAGGATTAAA CAGGGACATATTATAATGATAAAATGGTCAATCAACCAAAGAGATATAACAATTATAAAC ATAGTAATACACATATATTTATACAAGCACATAATATCGGAGACCCAAATACATGAATCA AAAACTGACAATCTAGAAGGAAGACATAGACAATTTAACAAAAATAGCTCGATGTGTCAA TAACCCACTTTTAATAATGAAGAGAACAATTAGTCATAAGATTATCAAGGATATGGAACA ACTAAACAACCATGTAAACCAACTAGACCCAATGGACTCCTGGAGAACACTTTACCCAAT AACACAGAACACACATTCTTCTCCAGCACACATGGAACATTGTACAGGACAAAAGTCTAT ATTTGAGGCCATAAAAGAAGCCTTAACCCATTTAAAAGGACTGAAATTATACAAAATGTT TTCTTTGACCCCAATGGAATGAAATTTGAAATCAAGGACAAGATAAATTTGGGAAATTTA TAAATATGTGGACATTAAGCAACACACTCTTAAATAACAAATGGCTCAAAGAAGAAATCA CATGAGAAATTAGATAATATTTTGAGATTAAGGAAAATGAAGACACAACATACCCACACT TATGGAAGGCAGCCAGGGCAATGCTCAGAGGGAATATGTAGCTGTAAATGTGTCTATTAA AAAAAAAACAGACCTCGAGTCGGTAACCTGAACTACCTATCAACATGGACGAAGAAGAGT TTAACTAAACTTTAAGCAACAGCCTTGCTTGGACCTTTCCCCTTCTTTCCCTTAGTACCT TAAGTTTCTTCCCCGGAAGAACATTTGCTCAGTATATCACATGCACTTGAACTGGTATCA GGCTCCGCTTCTAGTGAACCATATCTGACAACCACACACTAGCTGTGTGATCTTAGGTAA GACACTAATGTCTCTGTATATTGAAAATAATGTGTGTTTTGCCTACCTTGTATAGTGCCC TAAAAACAGTGGCTTGTTATTCAGAAGAATGTTACAGTGAGGTGGGCTTTACCACCCAAG CACCTGTGAAACCAAGAACAAGTAACTTTCCTGAACCTTTCTTTTTTCCCTATTGAGGGA TGTGCAGACAAGACAGACTACAGGGAACTCTGTCTTTCGAATAACATGCTGCCTGGATGT GGGAGCAGACGCTTCCCAATCTGCCCCTCTCTGGCTGCCTCCTACTGGAGAATTCTCCTG GCTTAGCTATTTTACGGATAAAATGAGAGCGATGACAACCACCTTCCATGGCTATGAAAA TGATTCCATAATAGCATGTGTACAAGTTTTGTAAAAAAAAAAAATGGCCTGGAGCGGTGG CTCACGCCTTTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGTCAGGAG ATCGAGACTATCCTGGCTGACACAGTGAAACCCCATCTCTACTAAAAATACAAAAAATTA GCCGAGCATGGTGGCGGGCGCCTGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAAT CACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCTCCACTGCACTCCAGCC TGGGCGACAGAGCAAGACTCTGCCTCAAAAGAAAGAAAGAAAGAAAGAAAGAAAAGAAAA AGAAAGAAAGAACGAAAGAAAGAAAAGAAAAGAAAAGAAAAAGAAAGAAAGAAAGGCAGA TAGTTAAATTATTCAACAAATATTGGATAGTACTAACCGATTACGTGTGTGCCATCTATG TGCTTGAAAGGAAAACCCTGTGTGGTTACAGGTCCTGTCATTGTCCCATTTTACAGAAAA GGAAGCATTCATGGGTGTCTCGTCAGTCTCTGTGGACGTAGGTGTGAAGTTTGAGAAAGT CTCGGCCTTCCCGGTACTCACAGTGCACTTGAGGGCTGGTCCTTACTATTTGTGGCTGCT AGGACATGGTAGGGGCAAGTTCCCAGAGAAGCCAGGTCCAAAGGGGATGCTCAGCTCAGC CAGTGACCTGAGTCAGAAGTGCCCTCAGAGGTTGGTCCCTTCAGGAAGGACGTGTCTACC CTCCAGCCCCTCCGTGGTCTCAGTGGGCACCAGATCTGCTGTGATGAGAACAGCCTGAGG GAACCACTCTGGATACCCCATGCTCCCGTTCTGACTCCCTCCCTCATTAAGACAGCAGGC GGGAGTGCTCTGTTAGGATGGAGGCTCAGACAGAATCAGAGAGTGCTTCATGGAGAGCAA ACAGTGCTTTCTGTTAACATTGAAAAATAGCCGACTGCTGTGACATCACTGCACACTCAC AATTACACGCAGAGACTTATCTGTGGGGCTCTGAGAAGCAAAGTCAGATCATGGTTAAGA AGTTTAAAACTCATGTCTCCAATCCCTAGGAGATGCTTCTTATCTCTGTTTGAAATTGAC ATTTAAAAGTTAATAGTTATGTTATTTAAATGAAATTCCATAGTTAATTTCCATACTGTC ATGAAGACAGGCTTTGCAATAAAAAGTTTCTGTAAATGGCAAGCCTAAATAAGCTGCAAA GATGAAGAAGATATTAAAAATAAAATTATATTTTGTGTCATTTCAAGGGCTTTTACTGTA TAAATCCATATTTAATCATCAATATAAGCCCAGAGACTCATATAAGGCTATCTTTAACTG TGTTTTGCAGATGTAGAAGCTGAGGTGTGGAGAAGAAAAGCTACTTCCTAACATCACAGA CTGGAAGCACCCAGGTCAGAATTGGAGCCAGAATGGTCTGACCCAGTCTTCTCTCTTACA GCTCACCACTGTCTCGTATTGTCTTTTAAAAATAATACTGGTTTGAGAGGAGAAGATTGA TTATTTATGTGTAAAGTAGTCACCCCATGGCCCAGGATGGTCTTATTTTGTCAAAAATAT GAACAGCAATTCCACTGTGCAGCGCACCAGTCTTGAGAATTGTTAACAAAACAATAAACT ATTGAATCATCACAACTAAAAAAAAATAAAAATAAAAATAAAATAATACTGTGTATCAGT CTAAGGCCCAGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTAGGAGGCCGAGGTGGG CGGATCACCTGAGGTCAGGAGTTTCAGACCAGCCTGACCAACATGGTGAAACCCCATCTC TACTAAAAATACAAAATTAGCTGGGTGTGGTGGTGCACGCCTGTAGTCCCAGCTACTCGG GAGGCTGAGGCAGGAGAATCGCTTGAAACTGGGAGGTGGAGGTTGCAGTGAGCTGAGTCC ATGCCATTGCACTCCAGCCTGGGTAACAAGAGTGAAACTCCATCTCAAAAAAAAAAAGAG AAAAAAGAAAAAAAATACTATGTATCAGTCTATAAAATGCTTAAAGTCTTTCTATTTCAT TTACTGGATGAAGGGACTACATTTTACTTGCTCTTGTTTTTCAGGGCTTCTAATGTGCCC TATGGCTAAAAGTCCAAAATTTTCAAAGAATTACCATGGAAACTCTCAATTTTTGGTCTC TAATATATTGAAATTTAATACAGACATCATTTCTGAGTCTCTCATCATTTTTGAAATAAA TGCTCAAAGCATGCCCCCAGCCTCACAAGGAGCCAGAGGGTTGTGGGAAGAACAGGTTGT GACTTAGCACAGTTTAGCAGCATGATCTATTGAGAGAAAAAGGCCCTTCTACAAGGAGGG CCAGGGGACTGGGTGGAGGTGGGGAAAGGGGAAGAGAGGGGAGGGAGGGAAGGGAGGAGG AAGGGGAGGGAAGCCACAATCACTGATGAAAATGCACTTTCCACCAGAGGGCGATATTTT TGAAAGCTTTGATTTGGTTGCACATGGTACAAAAATGCAGTCATGATAAGCAAAACTAAA ATATGTTCCTTTTATACTACAAATTTATACAGCAGTGAGTAAGAAAGATTGAATAAAGAT GAAAAAAGAGTTAGAAATACTTCCTCCTAATAAGGCTGAGGGAATTTACAACTATGTCAA CAGGGCAAATCTACAAAGGATAGCTTAGGAAGAAATGGACTGAAATTTGAGAAGAAAATG AGTTGAGCATACCAGGAGATTCAATTTCCAGGCCCTTGCAAAACGACAGACTGAAGATGA GCATCAGCCCTAAGAGGATCCCCGTGTAGGAGGCCTCTGTGAGTGTGCATGTCTGCCCGA CAGACGCCACAATCCCAGGAGCAACATTATAAACTGAAATAACGTGAAGTTCTTCTTTAC TTAAAGAATGTGGAGGGATTTGAATATCATATGTTACAAAACTGGATTTTGCCACAAATG ATGATGCACTGCCCACGTAATTTCAATGCCCACTGAAGGAGAACAGTGGCTTTGCCATGA GCAGTCCATAAACTGCCAATGACAGCTGGCCAGGTGTTGGGATGTGCCTGTTATACAAAT GTGCATGAGACAGAAGCAGATAAAATGGCGAATGAAAGAAATCCTACTACTAAGGAAAGA AAAGGAAAGTAAATGGGAACCATCAGATAGCTTTAGTTAGACATTCATCGAGAAAATAAA GGAAACAATTTTTCCTAAGTGCCAATGGTAACAATAAGAACGCTAGGAAACCTCTCAGTT TTCACAGGTTGCATCTTAGGTGTCTTCAGAGGATATGGCAGTTGTATGGACGTGCACAAG CTACTTACCTCAATTCCTATTTCAAATCCTCCACCAAGGCCAGCTATCCCAATGGCTGAG GGTGCAGACCATTCTAATAAAAAAACAAACGAACGTTATCCTAACATTAAAACACCCTCG ACATGTAAATATAGGAAGGAAAAATGCTAAAATCTAAAGAGTGCTTCTATTGAAAATAAT GAGACTTGGTATTTCCCCTGATTTTAAAGTGATCTTCAAAAAGAATATGTAATTTTTAAA AAGTTAAAAATATTTTTAAAGTATTAGATATTCATTATGAGTCTCATAGCCTCACAAGCC CATGTCCTCTAATCTTTCTCTACCAACATGCATAAGACCACCAACTACTGGTTCCCTAAC CATTAGCCATACAGAGCACTTGGTAACTTCAACTGTCAATATTTTTATAGAACAACTTAG CTGTAGGTCTAGTCTTCAGCTAGAATTTTGTCACAGATTTAAGAGATCAGAAGGATTCGA GAGAGTTGATTATCTAACGGTAACATAATAATTGTTTCCATTGTAAATTTCTGAGGGCAA AAACTGTTTTAACACCTCTCGTGCTTAAGCAGAATAAATAGGCTATAAATTCAAGGTTAT TAAAATTCTAACAAGATAAATCACATTTAGAAACTAAGTACAGTAATTCCATTTGCCATG ATACGGCACATTTTAGGATTACTATATGCTTATTTTTCTTGATATAGAAACTCATGTTAA ACAAGTCTAGAAAAATGTATTTTCAATTTGGTGGGGGGATGGTCTGGCCAAAGCACTTTT TGAAAATGGTTGCTACCATGCATGCTAGATACTAGAATATTGCTGAAATATATCCAGAAC TATCCTACCCAGGCTTAGAGAAGTTTGGCTTACAGAAATTAGTGTCTGATAATTTTTCGT TCCCTATGTTAGGAACTGTCCCTGTGTTAAGATGGCTGGTCTTGGCCAGGATCCTGGGGA ACATGTTGTGTCTTATTTGGACAGTTTTTAAATTACTCTCAGCAGAGTCAGCAGCTGCAG CTCAGGAAGAAGGGAGAGAAATGTAGGTTTTAAAACCAGTAGAAAGGTTTGCTGGGGCTC TGAGAGGAGCCCAGGGCTTGGTATTGACTGTCCCTACCCTTGGTCAGCAAGTCACCCCAT CAATGGAGCAGTTGGGGACCTGAGACATGCAGGGACTTTCTCACAGACTCTGAGTCCCAT CTGACAATGGGCTCCCTTGGAATGTGCCTCTACTTTGTTTGGTTTTACTGCTGAGAAGTC TGCTCATGGAAATTTGGATAATGCTTGAGAAAAAGAGAATTATTTTCTTCTCATTTTCAA AGCCACACATTGAGCTATGAAAACTGATCCACATAATAAGGAAGAGGTTTTTGTTGACTG CGGGGATACCTTGGTAAGAAATGGTGAATCTGCTGACTGCTATTTCAAGGCCATATATTT CACAAATGTATATATTGTATATTTATTGTCTGTAAGTGTCCCATGCTCTCTCAAAATAAA ATAAAATTATGCTAAAAAACTGCTACTAATAGAAAAACGTGTTCACTGAACAGCAAATGT TAAATTGGTATAAAAAACATTTTAGTTAGTTTTGACACACCTGTGTCCATTTTAAATACT ACTATAAATGTTAGTACTTGGGATTCATGGCAAATATTTTGATTTCATCTCTAAAGAATC AAGTAGTAGATTTCATCCCAGAAAGTAAAACTCGATGATACTGCTCTTGATATGATTCTG CCTTGGGGAAAACTCTTCAAATGTCACAGTTTTTATGATCTACCACAGAAACAAAGAAAT TCACATATGGCCCCTTATTTTCATATCAATTTCCATAAAACAAAAGAAAGCAGCTACACC ATGAAGTTGAGGAATAAGAATTCATATTAAACAAAAGAAATGCACATACTGCCATGTTTC AATATTTGCTCCACGGAAGAATTACAAAATGCATGCAAAACAAAGTTATATCTACCTGTC TTGTCTTCTCTAATATTTTGAGGACAGAGAGAGACGGAAAGGCTGGTTCCTGTGGCTTGT TCACTGACACCAAACTGCACGTTCAGTCGAGTAGCCCTTATTACATAAGTTTTAGTTGAT ATGCAGGAAACCTGTCCTACTCGCTATGCAATGTGTTCACATGAAAACAGACAGAACAAA GAATGAAGACTCTCTACTCCAGTGAACAGACGCCAACTTACTTCCATCTGGAAGGCGCGC CACTACAATCCCGCTGCCTCCTCTGGCAGTCACCAGGAACCCGGCTTTGATCACAGACAG AATTGCAAGGCCTTTAGCCTTCGCAATTACGTGAGCTGTTAACGTGGAAAACAATGGGAA GGTAAGCATTTTGATCTATGTGCCTGGATAGACGAGCAAGTGTTAAACAGAGTCAGTGTA CACAGAGGTTATCTCTAGGAATTCGGGGCACACAGGAGCAATGAACAAAAGTCAGTCACT CAACAGATGGGCACGAGGCCTCTCTATTCCCATGAATGTTTTTTGTGTTTGCTATTTTTG CAGTGCTAAACACAACATCATAAATATCCTCACATCCTGTAACTGACAAAATAAATTAGA TATTTGAAAGAGATTTTATTGCTATCTATTAGCAGGGCAAATATTTTGGCAATTTCAATT AATTTAGGATATAGTACATAAAAGATAAAAGCTACATTTTCAAAGAAATTAAGATCCATA TAGTATTAAGGAGAAACTTTAAAAATTACAAAAAGGCAGCATGAATTAGAACTTTGATCT TAAAGCCACGTAGCTAAATTAACCTTGTATTAATATAAAAATTTGGATTCAAAAACAGAA AAATTAAGTAATTTTCCAATGTTAAAACATTTTCAACTTTATAAAATGATCTGCTATAGC ATTTGAGTACCACTTAACTATTAGTACACTGATAATATAATTCCATTTAAAAATATTGGT TTATTCACATGTCAGAGATGTTCATTACATAAAATGAGGGTTATTGGTATATGTATCCAC TGAATATAGTGCCACACGATTCTGTGAATTTACGACACAATAACACCTCATTCAAACTAA CGAGGGAAGCCTAACATATAACTTTAAGGTAGTTTAACTTATTATTATTTTTATCAAATA TTCTGCCAAGGAAGTGAAGTCAGACATGGGGCTCTAGTACACAGAGCAAAAGCTTTGCAG ATGACCCAAGAGAACACTAAAATTCTCATGTAATTATGCCACCATTTCAAAGTTTAAATT AAGAACCGACTCTTGGAAATAATTCATCCAACACCATGAAGTTTGCATGCAGAACATTTG TGGAGCTGTTCTTAATAAGAAAGCTACAGAAAATAAGGTTGCATCCTGGATGGCTGTCTA CTAAGTGTACTTTATTTTTGTATTTTAAAAGGTTATAATTATATTGTAACAAGATTGAAA GCTGTATTATATGTTGTGCAGATTTATTTTTACAGCCACCTGTTGGCAGAATGTCTTCCT CACATTCTGTTCTCGATGCTTCTAGAGTTGCTATTGCCCCTATTGGGAATATTAGATATT AACAAAAGCACATTTTAAAATGGACATATTCCACATGTCAATTATATTTTTACAGATTTC CACTCAAATTCAGGGACACTAACATATTAATAATCCCTGAATAATCTGCCAATTAGCTTT TGATTTATAACATAGAATGTACCAATTATAGATTTAATTGCTAAATTAAGTTTCACCTAC TTCTTAGAATCCTAACATTAGAGGAGGCCAAACACACCACTGGGAAGGTTTTAAGATCTA GATGTCTTGTTTAAATATTTTGTAGATGCAACTGTTTATCCTATGAAATAGCATCTTTGT TTTAATGTAAACATAATGCCCCCCACCAGACTCCCAGGAGAAGTGGGCCTGGATCTCTGT TGGCTGTGGAACTTCCATCGTTGCCACACCCATGCTTTGGGGCAATCTCTTACTTAGACT AACATGCAAACAGAATTTCTTTTTCTGAGCTTCACCCACTGAGACGGGCTCCTTCAGAAT ACTGATACTGAAAATCTAGTTTTTCTTGTTGAGTTTTCTTTAAGCTCTAAAGCAGCGCTT CTGAAACTAGTGTGTGTGTGCACCTCACTGGGACCTTGGGAGGAATGCAGACTGATTTGT GACGTCTGAGCAGATTTCTCACAAGCTCCCAGGGGATGCCAAGCTGCAGATTCAGACTAT ACCTGGAGCAGTAAGGCTCTAACAAGCACCGTTTCCTCAAGACAGGAGAAGTCACCGGGC CAATGCAACAACAATTAATATCATGATTAAGATTATTAAAACAACAACAAATTTTTAAAG CATTAAAGTTCTATTAAATAACTTTAGATATCTGGCTTAGAAAAATTAACTTTATCTCTT TAATGCAGGACCCAGAGTCATGCACTCTGATTAACTAAGAGGGAGGCTGGTCTGTAACAC TGTCCAGGCTAACTGGCATGAGACAAGTATGCTATGAACACCCTTTGGAAATAACTAGAA GTGGTGATGAACAGATAGTGGTTTTCAAAGGCTCCCCTCTGGACTGATCTTATGTGTCAC TGACTACTTAAGAATTACATGAGAAACATGTTTAAAACATGCATTCCTGGACACACTGCA CTAAAAGTCTGATTCAGCAGGTTTGGAGTGAGGTTTAAGAACTGTGCCTTTATGGTCTAG GGGATACTGATGCACATCTGTGTTAGGAATTACTGATTAATGTCTTAAACCGCTAGAGAA TGTAAATGTCTTATGTGGAAGGAGGAAACACAAAATTAAAATTTATGTATGAGATTAGCT GGTGAGTTTGCGAGGTTAGCTTGCAGAGTTCTTAGCACGCGATGCAAAGGACAGGCGAGG CTGCAGAGAGCTCAAGTGGAGCAGGAACATGTGGTGTTTAGGGCGCTGGCACCCTGGGAT GGGAGGCAGGAGAAAAAGCCTATGCAAAAGGGAGAGACAGGGAGGGAAGAGGCCCTGCTG GTTTGCCTGGTCTGCAGCTGGCCCTGTCCAGACCCCTTCCACCTGGAGTAGCAAGGCCTT ATGATGACTGTTTTCTCATGATGGGAGAAGTGGCAGGAATGCAACAATAATTAATATCAT TATTTTATCATTATTAAGATTATTCTATCAATAACAAATTTTTAAAACAGAGCTCAGAGT CACGTGCTGTGATTAATTAAGAGGGAGGTTGGTCTGTAACATTGCCAAAGTTAATTGGCA TTTGGATCTCCTTTGCATGAAACAAGTTATGCTGTGAACACCCTTTGGAAATAACCAGAA GTTGTAATGAACAGGTAGTAGTTTCCAAAGCATCCCTGGATCAGTCATGAGAAAAAAGGT GGTGGAACAAAAGGTGGCTGAACTACTTGTTGGCATTGATGGAGGCTTCTGCCTGAAATG GAGTGTCGAACAATGCAAAAAACAACTTAGGAAAAAGACATTTAGAGACAAACAGCACTC ATCCTATTTACCTACCAGGAATGATCTTATCAGGTCCATTTCTGGAAGTTATTTCTGTGA ATTCTCTTAATATTTTGGCAGCCTTTTTTGCTTCTGATTTCAAATTGGAAGGTATAGGGT TATTCACTGAAACATAACAAAAGATATTTTAATGAAAAATTCTGCTAAATAGAAGTGAGA AATTTATTATTATTTCATTCTTCTCATATACAATTGTCAGAGGTGTTCAAACCAGAGGGA CTCCATTTTGAATAGGAGCTGGGTGAAATAAGGCTGAGACCTACTGGGCTGCATTCCCAG AAGGTTAGGCATTCCAAGTCACAGGATGAGACAGGAGGTCCGCACAAGATACAGGTAACG AAGACCTTGCTGATAAAACAGCATGCAGTAAAGGAGCTGGCCAAATCCACCAAAACCAAG AAGGCAATGAACGTGACCTCTGGTCATCTTCACTGCTCATTATACACTAATTCTAATGCG TTAGCTGCCAAAAGACACTCCCACCAGCGCCATGACAGTTTACAAATGCCATGGCAACAT CAGGAAGTTACCCTATATGGTCTAAAAAGGAGAGGACCTCTCAGTTCCGGGAATTGCCCA CCCCTTTTCCAGAAAACTCACGAATAATCCACTCCGTGTTTAGCATATAATTGAAAAACA ATTGTAAGTATCCTTAGTTGAGCAGCCCATGCCACTACTCCACCTATTGAGTAGCCCTTC TTTATTCCTTTACTTTCTTAATAAACTTGCTTTTACTTTATGGACTTGCCCTGAGTTCTT TCTAGCACCAGGTCCAAGAACCCTTTCTTGGGGTCTGGATCGGGACCCCTTTTTGGTAAC ACAATGAAGCATTACCACAGCATAGCCTATCAAAGGAAATGACTGGAAATCCTCATTGAC AGTATCATCTCTATTTCTCCTAATAAATCAAATCTATGCTGAGAGTCAGAAACTCTAAAC TCTCATCTCAGAAATTATAAAATCCTTGGGCCCCAAAGGATGTTAAACAAAACCTGGCCA AACCTCCCTGTTATGTATCTTCTTCCTGCAATTAACAGACTTCAATACTAATTTAAAATA AGAATTTAAAATTTAAAAATATATTTTGTAACTATCTATAATATATAGTATAAATTTAAT ATATTTTGTTGTTCTTGCCAAAAATGTTGGAACTGGCTGCCTGTAGACTTTCTGATGAGT AAAACTCTAGGAAGACTTGGGAATTGAGCCTACAAGTAACGCCGGCCTGCATTTCTATGG CACTTTACGTTTACAGTGTTGCCTGGACATTCATACACTCATCAGAGGGCTTGTCATAAC AAAGCTCACATAATTCTTCCAGCTCTGAAGTATATCGAGAAGATAGACTATTCTCTTGTT ACTGGACGAGGGATCAGCAGAGCGAAGAAGCTGAATAGCTTCAGTGTAGGACCACAAGTG CCCTGAGGCTGAGAAGTTCTTGTCTCACTGTCTACAATTAGGAGGCACATGCGTGACTGA CTGCAGGATGCCAGGATCTGGAAGGTTGAAGGCATTCATTTCCACTGTTTCGCCTCAGTA ATTTACAGAACAGAGATGAAGTACGCTAATGGAAGCTTGCTTTTGTAAAAGGAAAATAAA TCTCAGGACCCCAGAATCACTGAGCCAAGGGAAAAGTCAAGCTGGGAACTCTGTGAGGCA AACCTGCCTCCCATTTTATTCCTAAAAAGATAGCTACAAAGGTAAGAAGCTACACACCTC CCTCACAATTTGATCACAAGGAAATTCCCTGTGGACAACAGATGGAACTCAGACTCATCC CTCTGCTCACGTGAGACAAATGCATATCTGATTGTTTCCTTTGCCCTGTTGTTTCACTAA GCCAGACTACAGCCTAAGTGACTATTCCTGTAAATCACAAAGGCTAATCAGACACTCAAA AGAATGCAACTGTTTGTCTTCTATCTATTTATGATCAGGAAGCCCCCTACCCACTTCAAG TTGTCCCGCCTTTCTGGATCTAATCAATCTTACATATATTGATTGATGTCTCATGTCTCC CTAAAATTTATAAAACCAAACTATACTCAAATCGCCTTGAGCACGTCATCAGGACCTCCT GAGGCTGTGTCATGGGCTGTCCTTAACCTTGACAAAATAAACTTTTAAAATTGATTAAAA CCTGTGTCAGAGCTCATGTATAAACTCATGGTTTATTCTTTCGACAGATCAAATGCTGAA ACAGCAGAGAAAAAAATCCCTTTCTTTTATTCAGCAAAATATAAATATCTCCAATAAAAT GTGATATATTTTGGTGCCTGGAATGTTTGAAACATGTAATTTATCTTAAAAGTGAAAACT GGCTGGGTACTCCCAGCACTTTGGGAGGCCAAGGGAGGAGGATCACTTGAGGCCAGGAGT TCGAGACCAGCCTGGGCAACATAGTGAGACCCCCATCTCTACCAATAAAATGATTTAAAA AATTAGCCAGTCATGGTCCTTGCTGAAGTCCTTGCTACCCAGGAGGCGGAGGCAGGAAGA TCACTTGAACTCAGGAGATCAAGGCTGCAGTGAGCTATGACTGGGCTACTGCACTCCAGC CTGGGCAACAGGGCAAAGCCCTGCCTCAAAATAAAATAAAATTTTAAAAAGTGAAAACTG ACTTAGGGTCATTTTGGAGTTCTATTTAAATTTCTTTAAAAGATGTCAGTATCAGTTCTT TGTGGCTCAACACAGGAGTATTAACAAGATCCAGACCAGGAAAAAAATCCATCCCAAGAT TCATCAATGGTATTAAGTCAGATAGAGGAAGGTATTTCCACAGATACTTTATGCAAAATT AAGTGTGCATGATGCATGTGTGTAGCTCTTTACTCCTTTTAAAAACAAGTGGCATCACAG CATTAGTGTATTTTGGCATGTTGCATTTTTTAATCAATGTTATCTCAGAATAGTTAAAAT ACTGCCTCTCAGTGTAGGCTTTTCAAATCAACTTCATGAGATACAATTTACAAAATGAAA TCTACCTGTTACAGGTATAGCTCAGTGTGCATGGACAGAGGTAGAGACCACTCCTGATCA CAGCATCCGTGCCCTCTGTAGTGGTCACTCCTATACCCAGCCCCTGCCTCAGGTTAGTGC CAATCTGATTTCTGTCATTAAGTATGAATTTTGTCTGTGCCAGAACTTCATATAGTCATC AGTGTGTGTTCTTTTCTGTCTAGCTTATTTTACTCACCATGAAATTACTGAGACTCAAAT TGCTGCACAGATCAGCTCTTCCTTTTTGACTGCCAACTGGTATTCTAATGTGTGGACATA GCACAATTTGTCCTTCCAGTCACTGTTGATAGACAATTGGGTTGTTTCCAGCTTTTGGCT ATTACAAATAAAACTGCTATAAATATTCCTTTGTAAGCCTTTTGTAAAAAAATGTTTTAT GGCCGGACACGGTGGCTCACACCTGTAATCCCAGCAATTTGGGAGGCCGAGGTGGGGGGA TCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCTAACATGGTGAAACCCCATTTCTACT AAAAATACAAAAAATTAGCCAGATGTGGTGACGTGCGCCTGTAATCCCAGCTACTCAGGA GCCTGAGGCAGGAGAATCACTTGAACCTGGAAGGTGGAGGTTGCAGTGAGCCGAGATGGC GCCATTGCACTCCAGCTTGGGCAGCAAGAACGAAACTCCATCTCAAAAAAAAGAAAAAGA AAAAATGTTTTATTTCTCTTGGGTAATTACCTAGGATAGGAATTGCCAGTTCATGTGGTA AATGTGTATTTAACAATGTAAGGAGCCACCTAAGAGTTCTCTAAAGTGATTACACATTTC AGGCTTCCACCAGAAACTTTTATAAGAGTTCTGGTTATTCCATATCCTCACCAACACTTG CAATGTCCAGTTTTTAAAATTTTAGTTATTTTAGTGGTACACAGTGGCCTTTCACTGTGG ATTTAATTTTCGTTTCTCAGATGACTAATGATGTTGAACACTTTTTCCTATTTCTATATC TTGTAAAGTGTCTGCTTAAATCTTTTGTCCACGTCCTTTAACCACTTATTATTATTATTA TACTTTAACGGAGTTGTTTTTTTGCTTGTTAATTTGTTTAAATTTCTTATAGATTCTGAA TATTAGGCCTTTGTTGGATGTAGAGCTTACAAATATTTTCTTCTATTCTGTAGGTTGTTT TCTCTGTTGATAGTTTCTTTTGCTGTTCAGAAGCTCTTTAGTTTAAGTAGGTCCCATTTG TCAATTTTTGTTTTTGTTGTAATTGCTTTTGGCATCTTTATCATAAAATCTTTGCCAGCG ATTATGTCCACAATGGAATTTCCTAGCTTATCTTCCAGAGTTTTTACAGCTTTAGGTTTT ACATTGTTAAAACAGGCTAAATGTGACCTGAGAAGAACTCCATACTTCAATATTTGAGTC CTTGTAGATGAACTGCCACCTAACTTAATATGTAGACAAGATTGAGAACTTAACTTAGGA GTATGCATCTGTAACAATAGCTCAGTCTTGGCCAATCCCAGCAGCCATACTTCAACCACT CATACACTGCTAAGTGTTCACATAAGGAAAATGATGAGCTGTAACCAATCCAGTTGTTTC TGTACTTCATTTCTGATTTCTGTACGTCACTTCCCCTTTTTTGGTCTATAAATTTGTTCT GACCACGAGGCATCCCTGGAGTCTCTCTGAATCTGCTGTGATTCTGGGGGCTGCCCGACT TGCATATCATTCATTGCTCAATTAAACTCCTTAAAATTTAATTTGGCTTAAGTTTTTAAC AACATTCAAGTCTTTAATCCATCTTGAATTGTTTTTTTGCATATGGTATAAGGAAGGGGT CCTGTTTCAGTCTTCTGTGTATGGCTGGCCAGGTATTCCAGCACCATTTATTGAATATGG AGTCCTTTCCCCATTGCTTATTTTTGTTGACTTTGTCAAATATCAGATGATTGTAGCTGT GTAGCATGAATTCTGGGCTCTCGATTCTGTTCATTGTTCTATGAGTCTGTTTTTGTACCA TTACCATGCTGTTTTCATTACTGTAGCTTTGTAGTATAGTTTGAAGTCGGGTAGCATGAT TCCTCCAGCTGTTCTTTTTGCTTAGGATTGCCTTGGCTATTTGGGCTCTTTCTTGGTTCC ATATGAATTTTAAAATAGTTTTGTTTTCTAATTCTGTGAAGAATGATATTGGTAGTATAA TAGGAATAGTATTGAATCTATAAATTGCTCTAGGCAGTATGGCAATTTTAATAATGTTGA TTCTTCCTATCCTTGAACAAGGAATGTTTTTCCATGTTTGTGCCATCTCTGATTTCTTTC AGCAGTGCTTTGTAATTCTTGTTGTAGAGATCTTTCACCTCCTTGGTTAGCTGTATTCTT AGGTATTTTATTCTTTTTGTGTAAAATAGGTGTTTTAAATTGTATAATCTGCCATTTCTC GATCTGTTTTTGACTGATTCTTCTTCCAGCTATGGGTTATGTTTTCCTGTTTTTACTCCT TTCTAGTAAAACAGGATTGTAGATATTACCATGTTGAGTGCCTAGATTTCATTGCTTCCC TTAAAAGTGTTAACACTTGTGTTAGCAGGCAGTGAGTTACTTGTAGATCAGCTTGATCAC TTGTTGGCTTGTTGTTGTGTTCTGTTTGTGTGTCTAGAGTAGCCTTTAGAACTATTTTAT CCATCAAGGTGTGTCCCTTCTGGGCTCTCTCCTGGGTGCCCTGGTTGTTTAATAAGCTGT CTCCATTGTGGCTGTTTCGAATGGCTGTCCCCAGCCTGATGCAAGCACTGTGAATAGTTC ACCTCAAAGCTTCATGGCAGTTGTTCTTGCCTGCTTTGCAAATTTCACCCTACACAGCTA GCACTTAATATTCAGCAGAAGGCTCAGGGGGATCCCTCTGCAGATTTCTGGAGCTCTTTC TCTCAGCCGTCCCTCATTGCTAGTAACATGCTCTGCAAATTCCAGTTACCTCAGCCTCTT CAGACTCAATTTCTGCCTCTTCTTTTAAGCAGGAGCCTGGGCTCTGGGTGCCCCCTCCTT GTCCTGCAGTTTAGGAAGTGCTCCAGGCAGAAAACGGTCACTAATGGAGTTCACCTCCTG TTCCCCTTATCTTGTGGATCTCAGACATGTCCACCATGTGCAAAAAGTGCTCTACACACA GCTGTCCAGTTTCCTAGCTGTTTACCATGTGTGAGTAGCAGGAGCCATTTCGCTGCCCTG GCCAGTAGCTCTCAGTGCATTTTCCATTTGTTCTTTTATGATGAGCAATGCTGACCACAT TTCACTCTCTCTATCAAAGGTTTCTCATGCACCTTGTTATTTACAGGGGGTTTCTCTCTG TTTCTTATTAATTTATACATTAAAAATTAATATTTTTTTGGAATATGAGTTAAAAACATT GACTCTCTGTTACTTGTCTTTTGAATTTGCTTTTTTTTCTGTTTTTTCTTAATGAAATCA AATCTGTCTTCTATCTTACAAGGGTCTTTTAATAAAACACAGTAATTTTGAAGTTCAAAT GGGAAAATAAACAAGCAAGAAGAGCTAGGAAAAAATATGTAATAGGAGAACAATGACAGC CCAGCCTTGACAGAACCTGTGACACATTACAAAGCCTCAATAATTAATACATAATAGCAG ATGCAAATATAGGAGAAAAATCAATTCACAAAGAAGAAAATTCAGAAATTAACCCAAATA TATTTACAAATTTAGTATATAATAAAAATGACACCTCAATTCTATGTTGAAATGATGTAT TGCATACTAGATAATGTTCATTTGGGGAGAAAAACAAAAATTCATTCACAGCTTTGTGTT ACAGAAAGATAAACTCCAAATTCATTGAAGATTTAGAGTGTCAAATATCAAATTATAAAA GAACCAGGAATTATAGAATTTTTTTTCAATTTCATAGTGGAAAAGACCCAAGTATGGCAA CAAAATTTCTATATTTCTATATTTTTACATGATCAGCAATTATTTGTACAACGTACAAAT ACATTGTAAAATACAGGAAAAAGTACAGATATGAAAATATGAAGGATAAAAAGCATCTAT AACATTAATACTCACCAATACTACTGTCTGCATTTTGATGTATGCTTCAATTGATTCCTA TTGCGAAACATGTAGACTGATTCCACTTTTAGCTTTTATAGCCATTACTATCAGGTGGTA ATTATCTTGGGAGAGATGCTCTAGATGCTCAATATGTTTTAATTACATTTATACATATAT CTAGATGCTGGATACATTTGAATTAGTTCACTGGAGTGGAAACTTGTTCTTTCTGCTGCT GAATATTTCATCTACTTTATTTCAGAGGCAGCACAACTTGTCTGCTTACATTGATGCTGC AGCCATAGTATCTGGAGTGGATTGGGTGACCCGAGGCTGCTGTATCAGGACGACATTCCT TTTGGTGCCACAGCAGGGCTTTATAACCAAAGCTGGTCCAATACCAGCATCTGATGGGGG ACTTGTATAGGAGCTGCCAGAATAACTTTTTCCAAGGCACTTCTGTTTCCACTTGCTGTG GGATTTTTGTCTCCACAAGGGGAGAGTCTGAGAGCAAAGCCTTCATAGGGGAACCTGGCA GAAGGTGGAGAGAGCACCTGGGCTCTGCAAAGCCAGACTGAAGTCACAAGCCGCTCTGGA CTTCTTCGTCAAATGGACCAGCAACATCTTTTTCTGTTAAAGCAATTTAGACTAGATTTT CTGATACATGCAACTGAAGCACTGTAAATAATACATGAATCTTATCCCCTCAGAAGACTT TCTACTTTGAACTCTCTCAACCAAGCAGTATTAGAGCAAATAAGCAAATTCCTCAGTTGA GAGTTAATCTTGCAAACATCCTGCTGTAGGGAAAGGTCATGGCCTGATCTGTAAACACGG GAAGAGAGCCATTGGACTTGGGAATCAGATGCAGCCTCACACGGCTGCAGACCGCAAGAC TCATCCTAGACACAGCTTATGTCACTGTGATCCAGCTGTTGACAAGGCTGGTCACAGTGA GGACATCTTCAGTGTGTCAGCTGAACTACAGAAAATGTTACAGATTCTAATCAACTTCTG ATAAAATCATGCGTGGTCATAGTTACATGCAGTGAATTTCTCTGTCAGAACAAAAAGAAT ATGCAAATAAAAATTTAGACATAAGCCTCAAATCCCATCCTCAGCATCAAATGATGGCTC ACCCATTTTTCCTCTGCTGTACCATAAGGCATATAGAGCATGACCTGATCAGAGTGCTGA TGTCCCATTCTATCATACTGATGAAGACACAGGTCATTACTAATGAAGCCTCTTAAACCT CACATCATGGTTAGCATCTGCACTCTCATAAACGTCTTAAGTCCCTTGAATCAGGCAAAA TCTCTATAAATATTTAAGTTTTTTCTAAAAAAAGAGTGGCTGCCAAACCTCAAGCTAAGA AACTTTCAAATAAAGTTTTCTTTAAAACAAAAGTTAAAATGTTTTAAATTTTCATAGTAA CACATTTTTTTTTTAAATTAGAAGGTCTTATAAAATACCGGAAAGACAATTTTTACTTTG GAAACCTCAAAAGCATAAATCAGCTTAAGATCTGGAAATAATTTTAGGTATTGATCGCAG TTCTATAAACTCAATGCTAGAGTCACTGGGGACAAACAGGGACATGAGAATCCTACTCGG AGTAAATTGCCACCTGAGGTGACAAAGCTGACTACGGTTTCCAATCTAGTTGTACACGGA GGGTCAGGAATGAAAGCAAGAAGACCCAAGGGCCCCTCTCCACCACTTTCCTTACCAGAG TTCAGATTCCCAAACTTTTGCTTCCCTTATATTATTTTCTTCAATGGACTCTAATTATGA AAGGAATACTTACAGGAAAGCAAGCTTACTAAATTTGGTTTTCCAAGTTCTTACTGATTA CATATTAATCAAATTATTAAACCTTATACTTTATGTGAAATGGAGGTTAACTCATTAAAC TGATAAAATTCCATCTAAGATCAAAGGAACTTGAATGCTGCTAAAGGTATATTTAGAATA AACTAAAGAAATCTTAGCCAAAAGAAAGTGTATGTATCTAATCTTTAGAGAGGCTTTCAA ATGTTGCTTTAAGCTACTTTTATTAACAAAACTGCATTTTGAACTCCACTGCTTGACAAC TATGGCCTTTGTTTCTTAAGTCAATTCTTACCTTTCTGGGGCCTTGGTTTAACTACTTCC TTTGTTTTAAGGACACAAAGCTTGTCAGTTCTCAAAATAAAAACCTGTCTCTCTGGTCAG ATCATTAACTCCCTAGTCAAACTTTCAGACTACCGTCTGAACATCAAGTGCTAGCCTGAG CTTGTTTCCAGTCCCCCAACCCCAGGCTGTGGCTGGGGAAGGAAGAGGACAGCGAAAGCT TTCTCTGCTCCCTCGGGAGACAGGAAAGCCCTTTATTTATTCCTGCCCTTCCTCTTCTCC AACTGAAGAGTGTGATCTTGGTACAGAGCAGTTCCACACATGCCACACTGGTCTGATCTT TTAGAGTAAAAAATGGGATCTTCTCAGAGAAAATTTTTTTAAAAACTTCATGTGCTTAGG TCTCAGAGCAGAGAATTTTGTCTTATCATGACGCCACTCACTGGCAAACAAGCTGGCGTG CACAGGGACTTGTGAGGCTCTCAGCAGAGTCAGGGTAGCAGTTATTTCCCTTTGACTGCC TCAACTTCCTATGTTTGTGTTGACATGCCAGATCCTTATTTCTGCGGAATGAGAAATCTC TTGAGAATAAAGTTTTCCTAAACAGAACAAAAGTATCAAATCACTTTTGATGAGCAAACA TTATTTTAAACTTTTTTTTAACTTACAAAAGATGAGGGGTAACATTTACTAGTTTTACAG AAATTTTCTTTAAACAGAACATTAGTGAACCAAATAACCAATTCTCCTCAAACATGATAG ACAGGATGGAGGTTATCACTTTGATCATTTTAACCTCCAACATAGTAATTTGTAAACATC AGTCGCTGCACAAGTATTTTAATAACAGGCCAGCCCACGGGAGTAAACAGCACCTTAGCC TCGAGACCTGTTCTCTCAACTGTGTGTACAGATTTTCTAAGTCGTTATGAATTCAGATAT TCCCTACATCTCAATAAAAACACCTAGGAGAACAAGAAATCAGGACATGCATCTCCTGTA AGCAGAAGAGAAACCGAGCACCTGCTCTCTTGCGGGGGGGCAGCTTCGTGTCACTTTCCA ACTCAGCCTCCACAGGAGCATGGGCATATTGGTTCAAATGAAGTGTAAAGGACACATCTC TGTCCACAGTGTAAATCCTATTTCCTTAAGGTGGTCAACCGATTGAGACCAGTTCCACAC TTCCTTAAAGAAGGAAAAACTCAGCAGCCAGCGCCAAGGCCCAGCGATCAGAGAGGACCC GTGCTCGCCGCGACCCCGCGCTCGCCCTGTGGCCCCGCGACCCCGGCGCCAGGTGTTGGG GGGACCGGCCCTTCCCTTCCGGGTGTGAGGGGCTGGCCCTTCTCTTCCAGGTTGGGGGGC TGGCAAACTCGAACCTCGCCGGCGCCCTAGCCAAGGCCTCCTCCCCGCGCCTGCCGCGGG TTCCACGCACATTCCAAGCGCGCGCATTCGACCCAAACTTCAGAGACGCTTCTGTGGAAC GGAAGGATGGTCGCTGACACCTCGCCGTTCAAATATCAGGAAGTTAAAAATAACACGACC ATCGTCATCATTCCAAACTTCGGAATAGCTTTTCTAAAAATGGAAAAGACGGTGGCTAAA CTTCAATCAAAATCGCTGTGGTCAAGAAAGTCCTGGAAGCTGCTCTATCTTAACTTTGGG CGGTTTGCGGTTAACAGACGCGCGACCTAGAAACCCCAGAGGCATCGCCGGTTTTCCCGT CCTCCTCCTCCCACCACCGCCCAGCTCTTGAGAGGGGAGGGTGCTGCCGGACAGGTGGGT CCCCGGGTACTCACTGCTGCCCGCCCGGCCGCGGCGCCCCGTCCCGAGGCTGCCCAGGAA GAGGAAGGCGCGCTGCCCCGCCCCGCGGACAAGGAGGCCCCAGCGAGGGCGTACCTGCGG CAGGTGACGAAGGAGGCGGCGCAAAACACCCGCCGTGTACGTTTCGCGGGACAAAAACCA CGCGCCCGCCGGGCCGCGCTCAGGCCTTCGCCCTCAGGGACTTCGGAACCGCCCCGTCCT CAAGATCGAAAAGCCCAGAGCCCCGCGGCGGCTCCAAGCACGGTGTTGGGGGTGGGGGTC TCAGGGAGCGCCCAGGCCCAAGGCCGCCCTGGTCCGGCGTGGACCCCGCGGGGCTCAAGG CAGGTTCCCCGCGTGACCCGCCCAGCCCCTCTATGCGAACTCGAACGACAGGCACCACAG CCCGCCACGTGCGCGAGACTCGCGCTGTGCCCCAACCCAGGTGGGCGGCCCGCGGAGCCG CGAGGCCTGAGCCCGCCCTGCAGGTGACCCGCGGCCCTTCCTCCTCCAGGTACCCCTCTC CTGCGGCCCCGTCCCCTATAGGTAACCTTTACCTCCCGCGGCTCCTTCCCCTCCAAGCGA CCCGCAGCCCCGCCCCCTCCAGGTGACTCCCCCCCGCCAACCCCCGCCACCACACACACA CACCCCCTCGCCTTCCGCGGCCCTACTCCCTCCAGGTGACCCCACCCCCGCAGCTCCTCC TCCTCCGGACAACCTGCAGCCCCGCCCCTGCAGGTGAACGGCGGCCCAGTCCCTGCAGGT GACCCGCGGACCCTCCCCGCCCGTCCTACTACCGTCATAGGACCGCCTCCGCAGGCGCAC TGGAGCCGATTGCGCAGGCGTGGCTCTCACACGCGCTGCCCTGTTGGCGTTGGTGCGGGA CTGCGCAGGCGCGCGGGGCAAGAGGGTGGCAGTGCGCCTGCGCCGCGTCGGCGTGCGGAA CGCCGCGGTGTCTCGGCGCCTCTGCGCGCGGGAAGATGGCGGAACAGGCTACCAAGTCCG TGCTGTTTGTGTGTCTGGGTAAGAGGGCGCCGACTTACTCATGTTCTGACGTCCTCTGGA GAGTTGGATCGGGCTTGTGCGCTGTAGGTTGTGCCGCCGGCCTAGGAACCATGAGGGGGA GGAGGCCAGGGACTGGGAGGCCTAGGGTGTTCTAGGAGTGTGCCGCAGCGCCCCTGTTCC CCATCCGCCCCGTGCACCCGCCCAGCCTGCCCGCTAAACCTGGGTCCCCTCGCGCCTGCC ATATATCCGGGGCTCTTGGCATCTGCAGCCACAGCCCCTACAAGCCAAGGTACTTTCTTT GCGACTACTAGAATCCCTCTCGTTCCCCTCCAATGGGCCCAGGTAGGCCTGGAGGTTGTC GGACTGATGTGGTCTCTTAGGGGCCTCCTGAGTCCTATGACAACATTGTTTTGTTTGCTA GTTTCCTTAGCCCATGCTTAGATAGGGATCTGAGTTAAAGGGAGATGAAGTTTTACGGTT TCGGGTTTCTTGATTGTAAAAGCCAAGCAAAGGAGACCTGGAGGTCCCTATATAACTTTG GCCCATGAAAAATGAAAGTGTATTTTATTAATGGCTTTTCAGGAACTTTCCAGCTTAAAT TATTTTCACTCCTAGAATTTCAACACTTAGCTTGCCTTACTTCAAACATAATTTATTTTC CGTTTGGTCTTCAGGGATCTTCCTTTGGTGTAGCACTACAAGGTTATATTCCTCGGTGCC TCCACCCTGAGAGGAAGGCCTAAATTGTCAGTAGTCCGGTTACTTAAAACCTTCTGTGAG TTTGCATTTCCTGCAGTTTCTGTTTATTTTTACAGACTCCTCACTTTATCTCCTGTACCT TTTCCTGCTCACACCCTCGGGACACTGCCTTCCAGAACCTTTCGTTGTTCGGTAGCACTT CACATGCTTACTGAGCCTTCATCGCTGGGTGCCCATTATGCATTTTGCCTGGAAAGCCTT TTTATTTTATAAAGTCAAACCTAAATATTTCCTCCTTTGCTTTCCCAGATCATGAGTTGC TTCCTTATCGACATCTTTTATTACACAAATTTTACTATAATTTGTGTAATATAGTAAAAG ATGTAATACAGAAAAGGTGTGATTCCTTATCGACATCTTTTATTACACAAATTTTACTAT AATTATTTGATAGTCTGTTGAAATCCCAGCTGAGTTTAATTTTGTCGATGGCAATAACTG TGGCTTATTTTTCATTTTGTTTTCAGCTTTAGGACAATATATGATAAACGCTGACTAGGT TTTGTAGAAGTTAACTTCTGTGAAAGACGAATTAGAAGGCTTACCTTGTTTCACATTGGT AGTGGGCATCATTTGATTTTTAAGACTCATTGAAGGCTGAATGATGAAATCAATAAGTTT ATTAAACAGTAGTTTGGTTAAGGATGGTTACTAAATAATATTCCATTCC bcftools-1.21/test/csq/ENST00000479739/ENST00000479739.fa.fai000066400000000000000000000000211467060157400215660ustar00rootroot000000000000002 48709 19 60 61 bcftools-1.21/test/csq/ENST00000479739/ENST00000479739.gff000066400000000000000000000070531467060157400212200ustar00rootroot000000000000002 ensembl_havana gene 21 48689 . - . ID=gene:ENSG00000035115;Name=SH3YL1;biotype=protein_coding;description=SH3 and SYLF domain containing 1 [Source:HGNC Symbol%3BAcc:29546];gene_id=ENSG00000035115;logic_name=ensembl_havana_gene;version=17 2 ensembl_havana NMD_transcript_variant 1071 42999 . - . ID=transcript:ENST00000479739;Parent=gene:ENSG00000035115;Name=SH3YL1-009;biotype=nonsense_mediated_decay;havana_transcript=OTTHUMT00000322358;havana_version=3;transcript_id=ENST00000479739;version=2 2 havana exon 1071 1292 . - . Parent=transcript:ENST00000479739;Name=ENSE00001954076;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001954076;rank=11;version=1 2 havana three_prime_UTR 1071 1292 . - . Parent=transcript:ENST00000479739 2 havana exon 12257 12335 . - . Parent=transcript:ENST00000479739;Name=ENSE00003606733;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003606733;rank=10;version=1 2 havana three_prime_UTR 12257 12335 . - . Parent=transcript:ENST00000479739 2 havana three_prime_UTR 12838 13259 . - . Parent=transcript:ENST00000479739 2 havana exon 12838 13482 . - . Parent=transcript:ENST00000479739;Name=ENSE00001945985;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001945985;rank=9;version=1 2 havana CDS 13260 13482 . - 1 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 2 havana exon 15392 15520 . - . Parent=transcript:ENST00000479739;Name=ENSE00003685079;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003685079;rank=8;version=1 2 havana CDS 15392 15520 . - 1 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 2 havana exon 16451 16563 . - . Parent=transcript:ENST00000479739;Name=ENSE00003571637;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003571637;rank=7;version=1 2 havana CDS 16451 16563 . - 0 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 2 havana CDS 25089 25091 . - 0 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 2 havana exon 25089 25162 . - . Parent=transcript:ENST00000479739;Name=ENSE00001537032;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001537032;rank=6;version=1 2 havana five_prime_UTR 25092 25162 . - . Parent=transcript:ENST00000479739 2 havana exon 25794 25853 . - . Parent=transcript:ENST00000479739;Name=ENSE00003646899;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003646899;rank=5;version=1 2 havana five_prime_UTR 25794 25853 . - . Parent=transcript:ENST00000479739 2 havana exon 29829 29893 . - . Parent=transcript:ENST00000479739;Name=ENSE00003541607;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003541607;rank=4;version=1 2 havana five_prime_UTR 29829 29893 . - . Parent=transcript:ENST00000479739 2 havana exon 32022 32135 . - . Parent=transcript:ENST00000479739;Name=ENSE00003498940;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003498940;rank=3;version=1 2 havana five_prime_UTR 32022 32135 . - . Parent=transcript:ENST00000479739 2 havana exon 35296 35406 . - . Parent=transcript:ENST00000479739;Name=ENSE00003522422;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003522422;rank=2;version=1 2 havana five_prime_UTR 35296 35406 . - . Parent=transcript:ENST00000479739 2 havana exon 42376 42999 . - . Parent=transcript:ENST00000479739;Name=ENSE00001878590;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001878590;rank=1;version=1 2 havana five_prime_UTR 42376 42999 . - . Parent=transcript:ENST00000479739 bcftools-1.21/test/csq/ENST00000479739/short-cds-start-lost.txt000066400000000000000000000002561467060157400234530ustar00rootroot0000000000000025091 T C start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C 25091 T C start_lost&splice_region&NMD_transcript|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C bcftools-1.21/test/csq/ENST00000479739/short-cds-start-lost.txt-l000066400000000000000000000002561467060157400237040ustar00rootroot0000000000000025091 T C start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C 25091 T C start_lost&splice_region&NMD_transcript|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C bcftools-1.21/test/csq/ENST00000479739/short-cds-start-lost.vcf000066400000000000000000000005351467060157400234120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 2 25091 . T C . . EXP=start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C;type=ENST00000479739:242800-T-C 3bp CDS bcftools-1.21/test/csq/ENST00000518414-ENST00000521270/000077500000000000000000000000001467060157400204575ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000518414-ENST00000521270/ENST00000518414-ENST00000521270.fa000066400000000000000000000265561467060157400244350ustar00rootroot00000000000000>8 8:182402-193821 CGAGGTCCGCTCGGGTGAGTGCCCTCCGCTTTTTGTGGCCAAACCCAGCCACGCAGTTCC CTTCCTGCGGCGTCCTCCACACCCGGGGTCTGCTGGTCTCCGCGGATGTCACAGGCTCGG CAACCGCCCTCCTGTCGGCGGGGAGTCCCGCGACGCCCGGAAATGCTCCGAAGCCTGTCG CCCAGCTGCCAGATCTGCGTCTGTGTCCGGTTCCGTCACTGAGGTCGCCCCTGTCCGGCC CTTCCACCCTAGTTCTCTTCACCGTCCGCCCATCCTATCGCGCGCGGCCTCAGGTCCCGA TTCGGCATGTGGCTTGTCTTCCATCGTCCCCACCCTCGCCCCTCTTGGCCCCTCAGGGCA GCCCTGGGATTCGGCAGACGCCAGTCCTCCCTGAGATGCTTCCCCATCCTTCCCTCCGCC AGGCCCTACGTCTCCGCAAACCCCACGCTTCGGGGTGGCCGCCTCAGACAGGACCCTGAG TCCGAGACTGGGGTAGGGGACCTGCCCGATCCTGTAACAACCCTCGTGCTTCTGCACAAT CGCCTCCCACTAGCGGTGACTGTTGGGTGTTTACCTTCCCGGTGTCCCACTGAGAAGCGG GCTCTTCCTTGGCAGGGGCTTCTTCATTGCCTCGCTGTGGATGTCGAGGTGGGGCAGGAG AGTGAGGAGAAAACAGAGGAGGGAGGTAGAGCCAACGAGCGAGAAAAGGGGAGGGAAGTT TAGATGGGAAGTGGATGGGTCTGAGGAATTTGAACAAACACCGACAATGAAGGAGAGTGA CCTGAGCAAGTAGTAGTGGGGTAAATGGAAATAGACAAAATGGGAATCAGCAGAGATATG GAGGACAGAATACAATGAGGAGGCCTTGACCGTCAGTAGCAGAGAGGGCAGCAGAAGCCT AATTCCCAAATTCTTTAGATGGTTTTCTGATTTCCAAATTAGTTTCCCTTTTAAATTTAT TGTGTCAGGTTCAGCTTATGAGGCCTCAATACTTTTCAGTCTTAATTGTATATTGAAAAT ACTTTTTGTTTACTAAATGCTTTTTACATTAATTCAGTGTGCACTTCGTAAGGATAATGA TGATTTGAGTTAGTTTAGTATTCAACAGCTTCCTCTATTCCTTTATATGATCTCTGTATT TAATGGCTGTGGCATAAAGTTTCCAACTAAGTTTAAGTATCAAGTTTTCTTTGTGCTGTT TTCTGCAAATATTGAAGGATGACCTGGATTGTCCTAGAACTTTGTTCCAACAGATTACAT GTGTTCATAATGAATAGACTGCTCAAAGATATTTCCAAAGCTCACCTTTTATGTTTTTCA GTTCCAATAATTACATCTTTTTAAGGTTTATATTTTTTGATGACTTAATGTGATGTTCTG GAGAAGACAAATGCTTTTAATCAATATGATTAAAACCGTGAAAGACAAATCGCTGTTACT TAAGAGTGTGACATATGATCTGAAATCTTTAGGGGGCAGGGATGTTAAGGGAAAACTGCC ACTATCGTATTAAGGTCATGCCATTCCTGTGAAGCTGGTGCTTGTTACTCTCTACTGGCT TCTGTTCACCTTTCCACCGGCCCCAAGACACACACATAGTGACACAAGGCAGTGGACAGG GAAAGAGCAAGACTTTATAAAGTAAGCACACAACAAAGGTATCTTTCTAATGAGGAGGAG GTGTTGGTTCTGGGAAGGAAGCTTGGGATTTGGGTATTCAGGATCCAGAAGTGAGAGAGC CTGGGAAGTTCAGGAACCAGAGAAAGAAAAAGCCTTGCCCATTCTCACCCATGACACTGT GCTCAGCAGGTACTAGCAGACTTCAGGCTCTGTGACTAAAAGGGGTCAGACCAGTTGATA TACCCACAGCTGCCATGTAAGGATGTGTGTGGACTTCACTAGGGAAGAACGGTGTTATGA AAGAAGGGGCAGAAAAACTCACCTGTTGGTCTGCATGTAGAGGTTTATTGTCCTGAATTC CTGGAGGTTCAGTGAAAAGCAGAAGATTGTCTTTTACACATGTTGAGTTATGCCCCCATA TATGTGGTTGTGGTAAAGAAAGAGGGTGTGTTGATGAGAGGTCCTGAAATGCATTTTCCT AATACTCAGCAGGGGCTTCTCAAGAAGGATCTTCCCTAAGAAAGAAGCTCAGAGAACAAA AATGGAAAAGGATTAGATATGGCACTTTCACTGGAAAAAGTCATGTTATTCATTGATTGT TTTGTCATCTCCCGCCTTAAGTGTTGTTTTTAGGATGTGGTAATCTCTGACCCTGCCTAA CACATTTCCCAACTCACCCATAGCCTTCCCTTAACGTCCTCCCATCTTCACGCTATCACA CTGTGACCCAGTGAATTCGAACTTGTGAAGTTCCATTCGGGGGATCATATGGGAAGGGCT TCACACCCAGACATAGATTATAGATGGGAAGTGGGCCACATGGTGTCAGTGAGGCAAGTA TGGGTCGTTTAGGGACAATGCACTGTCAGATCTTTGTTGACCATGATTAGAGAAACTGTG CATATTAGTAGTGAATTAATGTCAGGAATATCTGACAAATCCTGGAAAAGAAGATTGATG AGAGGAAATGTGTTCTGCCCAACTGTATAATGCATTTGAAGCTTAAAACAATGAATCAGT ATTGATCTGGCCACAAAATATTAATGATTTGAATTAAAAAGAAAAGTTTAGAAAATGATA GCTTTGACAAATTAAGGTAGCATTTCATCCACACGATGGAGTGTGTTTTATTCAGTAATT GATTTAAAAATGGAATCAACCTAAGTGTCTAACAGGAGGGAGTTTTATAAATTGTTCACA GAACATCTGTTCCAAGGAGACCTTGATGTTCATAGATTTGTAAAGAATGCTGCTTACTAG CACACTGACTGCTCTGCAAATGTCTGAGGGTTCCTCCACTTGGGGCAAGTTGGGGGTTTG ATCGCAGAGTAAATAAATGGTGCATTTTATAATGTAATATATTCTAGCAAGATGCAGCCC ACAAACTGTATAGATACTCTTATGTACCACATAAAGTTCATCTACTACTTTAACCAGAAC TTGATACTGTATGTATGTTTTTTTTTTTTAGATTTGGATAAAATGACAACTCATTGTTAT TTCCAGTTCACAAAGTAATTGTGAGGCTGAATAAATTTTATTATTTTATAGACATATGTG TAAAATGAATTTTTCTATGAAACTCATTTTTGATGTATATTAGATGCTATTTTATATTCT GTAGTTTAATTATATGTACGCACACACAAACACACACTTCGGTGTCTTATTATGTTTCTG CAGTGAAACCAAAATCCTTCCTTCACGCCCTTTGATTTTATGTTTTCCTCAGGAAGGCAG GAGCTATTGTATATGATAAAATATTATGTTTTATTCAGTCCACTTATGAAATTGTTTAAT ATTGTTATAAATATTTATATGACTTATTTTAAATTTCCAAATAACATAGGTTACATGAAA TTTGACAACTTTATTTTTTTCTTTTCACAACTATTTTGACTGTATACTCACCAAAAATCA AAATTTAGACAAAATTGACTTTTAGACTAATTCTCATTTTTTACATGTAAAAGACCACAT GGGACTTTTAAGTCTAGGTTGCCCTGAGTCTACAGTCACTGAGGTTTTATGTCACTATGT CCTCCATTCTAATAATAGGATTTTCAGGCTTTATTCATGTCATTTTTATATCCTCATTAA GTTTTAAAATTTATTTACATGGGTCTACAAATTTATTTCAAATCGTAGTCATAATATTTG CCTGTTGTAAATAGACACTGATTTTGTGTGTTTGCTTTTTTTAAGGACTAATGTTGCTAA ACAGGAAATATTGATTTCAGAATATTCATAATAGTTTTGCCCACTTTTTAAATATTCTTA TTAGTATTGATAATTAGAATTGATTCCACTTTTTCAAGTTTACAGTCACGTCATCTGAGA ATAACTACAGTTGCAGCTCTTTGACTCCATTTTTGTAGTCCCTCTCCTTTTCCCTCTTGT TTTGGTCCCACCTCAGGCATCATGTGCAGTGGTGAATGGCATCAGCCTCACCCAGCCTCC TTTTTCCAGCCTTACCTTTAGTGGAAATGGTTCTTTTGTTAACTGCTGAATATATTGTTG AGATTTTATTGATTAAGAAGAATTAGTCCCCACAATTTGGTATGATTTTTAAAGATTTTA TATTATTTTTAAAGATTTAAATTATATGAAAATGTTTTTTCAAAGGTCTATTAATGTGAT TTTTTTAATCTTTAAAATTACTTTGTGAAAATGATAGGTTTTCTAGTATGGAATTATCCT TTTATTATTGCAATAAACTCCACTTTACCATGCTCTGTCATTATTTAACCATACCAGTGA TGGCCAGGTGGCCAAAATAAATAGCCAAATGGCTAAAATTGTATTGATGATTTTTGCAAA TGTAAGTAAGGAAAATTGTTGGTTAAATTTGTAGTTATTGTTACATTCATGTTCATTTTG ATTAGCATAATAAACTAATGAGGACAGGCTTATTTTTCTCCTTCAAAATAACTTAGGTTA CAAAGGAACTAGAAGTGATTTCACATGTAAGAACTCTCACAAATCACTTTTACAGTTAAA CTCTGATATATAACTTAAACATTAAAATTGGCTAATCAGATTTTTGTGCTGATTAATGAG GGAAAGTTTTTACTCTTTTTGTGGAAAGTAATATACATATTCATGTTGGAATATAATTAT TCCCATTTCTTAGATTTTAAATTACTACTTTTAAATAAATACAGTCTCTTTTATTAACCT GTGTTTTTTCTTTCCACCGTGGGTCTTTTCAGTTTCATGATTTTGCTCTCAAAACTTTTT AATTATTGATTTCTGTCAAATCTGTTCATTCATTACATTATTTTATTATTTATTAAATTG TTTTATCTTTTTAAGTCTTATTAATATGTACTGAATTTGTAACAATTTGGAAAGTCAAGT AACTCCTGTTTTATCTTTTTCTTGGTTTATGAGTGTTTTTAAAGTTTTACGTTTCTTGAA GATCACAGCTGTAGCCCCAATTCCATGGTTCTGGCTACTTACATTTATCATACTTATTAA TATCATGAATGTAATTGGAATACCCCTTTGATTTTACTGGTGACGTATACCCACTAGTGT ACTGAGACGGAAAAAAAAGTCTTTAGAACTCAGATAAATATACAGTTCATATTTACTATT TATGTATGTGTGATCTCATTATTAAATTACTCTATCATGTTTGTGGAATTAGCAGTTTCT CTTTGAATTTGGATGTTTCTAGTTATGTGTATTTCCAACGTATGTTTTTAGCCACATACA CTTTATTGAATATCATATTTGGTGTTTAATTTTTGCTAGGATTATAGGCTGGACTCCAGA TCCAAACTTGACATGTAGCAGACCCATTAAAAACATACATTAAGCCCCTAGCACTGTTTT AATCTCCATGGCCTGGCTGAGCTTCTGCCATCTGTCTTCCTAGGCACCATGAGGTCTGGA CATCTCATTTGGCATAACTCAGCTGTGGCCATTGGTGGATCTCATCCTTAGTACTAGTCC CTGCTGGCAGGGGTGACCCAGGCCCACATAAGCCATTGCTGGCCTCCTTGGAGGACTTAG AGAATCCTGAGATTGCCCATGAGGATGGACATGCCTTTCAGTCTAGCACCCACCTTTAGT GATGCCTGTGGAGATTGAGAAGCTCACAGGGGCCTTGGATGTCTTTCTTATACCTCCATT GTCTGCAGCGTGACTCCCATACTCTTGAGCCAAGGTAGAGAATTTTTAGGAGGCTTGTGT GGAGGTTTATGGTGGCCCCCATGGTTCTGTGAGACTGGTAGAAAGCACAGACCCCTTAGA CTTCTCCCCAAGGAGAATACGTGAGACTAGTGGAGGAAAGGAGAGTAATGAAATATGCAT TTCGTGTCCCAGGCTATCAGAGCACAGCTCTAAGGAAAAATACAGGGCATCGTATAGCAA CTGGCACAGCTCTGTGAGACTGGGAGATATTGCACAACCTTGAAAAATCAAGATGTGACC CTACTGAATGAACAAAATAAATCTCCAATAATTGACCATAAAGAAATACAGGTTTCTGGC TGGGTGCGGTGGCTCACACTTGTAATCACAGCACTTTGAGAGGCCGAGGTAGGCAGATCA TTTGAGGCCAGGAGTTCAAAATCAGCTTTGCCAACATGGTGAAATACAAAAAAAAAAAAA AAAAAAAAAAAAAAAATTAGCTGGTCGTGGTGACGGGCACCTATAATCCCAGCTACTCAG GAGGCTGAGGCAGGAGAATCACTTGAATCCAGGAGGTGGAGGTTGCAGTGAGCTGGTATC GTGCCGTTGCACTACAGCCTGGGCAACGCGAGTGAAACTCCGCTTTAAAAAAAAGAAAAA GAAATGGAGGTTTCTGATTTTCCTGATAAGAATTACAGGTAATTGCCTTAAAGGAGGTCA ATGAGCTATGAGACAACACTGATAACAAGTAAAATCTGGAAAAGGATACATGAACAACAT GAGAATATCAACAAAGAAAAACCATAATAAAAGAATCAAATATAGATTCTGGGGCTGAAG AATACAGTAACTGAACTGGATCAATACAAGGCTTCAAGAGCTGACTTGATCAAGCAGAAG AAAGAACCAGTGAACTCAAAGACAGGTTATTTGAAATTATTCAATCAGAAGAGCAAGTAG AAAAAGAATTTTTTAAAAGTGAAGAAACTGTCTGTCTTTGCTAAAAATTGGAGGGTCCTA AGAACTCCTCCCCGCCCCCACTGCCAATGCAGAGTCTTACTCTGTCACCCAGGCTGGAGT GCAGTGGTTCGATCTCCGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCATA CCTCAGCCTCCCGAATAGCTGAGATTACAGGTGCCTGCCACCATGCCCAGCTAATTTTTG TATTTTTAGTAGAAACGGGGTTTTGGGGTTTCACCAAGTTGGCCAGGCTGGTTTTGAACT TCTGACCTCAGGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAG CCACCATGCCCGGCAAGAACTCCTTTTTATGTTAGATTCACTAGGGTTTAGCAGCTCACA GAACCCAGGAAAACAGTTTACTTAGCTGATTTATTACAAAGGACATTTTAAATATTACAT ATGAACAGCCAGCTAAAGAGTTACATACAGCAAGTTTTGGAAGCATCTTAGGTTTAGGAG GTCTGTCTCCAAGCAGTTGGGGGGTACCATTGTTTCAGCATATGGATGTGTTCTTCACCC ACCCAGAAGCTCTAGGAATCCCATCATTCAGGGATTTTTATGTGGTGTTCATCAAGTAGG CATAATTGTTATTAACTCGATCTCCAGCCTCTGTCCCTTTCCCAAAGGATAGGGGGTGGG ACTGTACGTTCCAAGCTTCTGATCAAGTCATGGTCTTTCAGGTGATCACCCCCCATCCTA GAGCCTAGTAATAATTGTCTCATTAGAACAGAAGACACTCTTATCACCTATGAAGTTCCA AGGCATTACGAGCTCTGTACTGGGAACCAGGGTCAAAGACCAAAAAGAACAAAAGCTTCT CCTAGCAACTCTGTTGCTTAGGAAATTACAAGGGTTTTGGGTGGCTCTGTGCCAGGAACT GGGGATGAAAACCAAACTATCTATTTCTTACAACTAACAATGTCACATACATGTTCAAGT TTTCATGTTCTTAGTGTCCTTTCATTTCAACTTGAGGAACTCCCTTTAGCATTTCTTGTA AGGTATGTCACTTGTAAAGTGTGTCTTTTAAGGAATCCACCATGATAAAATGAAATTTGA AGCTGCTTGGTAGATAAATTCATGCTACATTTATCTACAGGTCAGACTTGAGGGACTGGT ATTTCTAGAAGCCTCACATGGAAGAGACAGAATCATTCAGTACAAGTGTATCCAGAGGAC CAGCAGAAGGGAGAAGGAATGGAGGGAGGCTCCTGAGGGCTGAGATGCATGTGGAGAAAG CCTGCAAGCACACAAACCGAGAATAATTAAATCTGAGAAATTCCAGGATTTATCTGTAGG TGGAGCCACATCTCCATGATTCAGGGATTCTTAGGATTTGGAATCATAGAAGGAATTAAA CATTTCAGAATTCCATGCGCTAGGTGGCATATGAAACTCCATGATTTTCACATTTCTAGG TCTAAAATAAAAATATTTATATCTTTATTAGCAGCAATAGTCATTTCTTCTGACCCTGGG AGAGGAGAGCCACCAACCCAACCCACCCCCTACCCACTGCATGTCCTTGTTGGTTGGACT GGGGCTAATAGCTTTGGGGCAGATGTTAGAAGCAAAACTGGAGTGTCATGGTTTTTTTGT TTTTGTTTTTGTTTTTGCTCAGATTTGTCTTCTTAGTGCTTGGATGGTGTGAGTGAAAAC CCAGAGGAATACATTTGGTGGCTGAGCTAGTACAATGCCATCACCGGTGAGTGGGAAATT CTTCTTTCTACTGAAATTTGTACCCCTGTTACCAGCCTAAGGGCAGATTCATCCTATTAA CATGGATGTTCTAAGTGCACTCAAGGATCCAAGCTCCAATTAAGATTCCCCAGGGCTTCG GAATGTTTACATTGGCTCAAAGAGTCATCAAGAAGTAATGTCCTTTCAACAGTACACTAA GGCATTCCAGCCTCTACTAAGGCTGTGTATTAAGATGTGAGAGGTTTTTGTTTCTCTCAT CCAGTCTCAGGGAAATCATTCATTACGAGCCTCTCATGGCCTTGTTGGGGAAATAAATTC ACTCATTACCTATGTTATTGGCAGGAGTGGGCTTGAGAGTATATGTGGGTAGGTGGTGAA AATAAGTGAGAGCAGGTTATAGCCCATACAAAGGCAAGCTCAGTTAGTCTAGTGTTTCAG GTGTTAGGGGAGGGCTGTTTAACTTGAAGGGAAAGCAGATAGGGTTAGGACAGAGGAGAC AATGAGGAATTATTCATTTATTTTTCCTATCTCAAAATCTTAATGTCTTGAGAGAATAAA TGTGAACTTTTGAAAAACTTAAAAAGCAAAATTAAAATTCTTATTACCCTTGTCCCCAAA TTAACCTCTGATCAAATTTGATAACTGGAAGCAACTGGAGTGTTGTTTCTTTAATTTTGG TTGTGCATTAAGTGATGGAGTATAGGAAACAGAGTAAATTTAAAACTCTGAGGAAATTTT TGAAGTGGAGAGACCAGGACAATCAAAGGATTTTTTTTCCCCTAAATCTAGAGACAACAT GAAGAAACAAAATAGAATAGTACCTAGTGCATTAGTCCATTTTCACACCGCTATAAAAAA CTACCTGATAGTGGGTAATTTATGAAGAAAAGAAGTTTAACTGACTGACAGTTCTGCAGG CTTAACAGGAAGCATGACTGGGAGGCCTCCAGAAACTTACAATCATGGTGGAAGGGGAAG CAAGCACCTTCTTCATAAGGCAGCAGGAGAGAGACCAAATCAGGAAATGCCACACACTGT TAAATCATCAGATCTTCTGAGATATTACTAGCATGAGAACAGCAAGGGGGAAGTTCACCC CCATGATTCAATCACCTCCCACCGGACCCCTCCCCCAACATGTGGGGATTACAATTCAAG ATGAGATTTGGGTGGGGACACAGAGCCAAACTATATCACCTGGTGTTTGAAGATCCCACA TAAAATTGAGAAAGGAAATCCTCAGACCATGGAAAGTGGCAGGATGAGACCATCTTTCAG TACTGAAGTCTTAGAGTCCCTGGCTTGTGCTGCTGAGCCATTCATCCTTATCCATTAACA GTGAACACCTGAGTTGTGTAGACATAAGAGGCTGCATCTGCTGATACCAAGTTCTATATG AAAGTTGTTCACACAACTGAGTGTTCTCAGTCATTTCATGAATAATGTATTTGTGGCTTG TATCTAAAAAGTGATAGATAGGAACCACTTTACATACTATCTCATTGGACCTTTTTGAAC TCATAACAGGTCTTTATTTTATTCTGAGGACACTGAGGTCCTATAGTGGAATATCTAACT ATAGTCTTGATTAAAACGTGACAAATTATGGATGCTGCCTCCCTTGTAGTGAGTCTATAG ATTTTCTTGAAGGTGGTGGAGAGGAGAATTTTAGTTCTAAATTTCCAAGTACAGATTTCA TAATTAGTATCTGTAAGTTATACTTTAGAAGTCTATTGGGAAATCTTCAGGTTATATTAT GCCACACCACATGTGATATTTCTCTATGTGAAGTTTTATGTATGAGTAAATCTGAAAGCC AGATTCCCAGTTCAGATTTAAAGCAATGTGACAGGAACCCCAAACACTGTTTTGAGTTTT CTGTTCATACCACCCACACTTCCTTAGTACAGTCACTTTGATCTTGCTCCACTGAACATT GGCAGAGATAGCCCTGTTTGCAGTAGAATGTCCATAATGTTTTAGGATTCCATGACCTTC GAGGATATCATTGTAGACTTCACTCAAGAAGAGTGGGCCCTGCTGGACACATCCCAGAGA AAGCTGTTTCAAGATGTGATGTTGGAGAACATCAGTCATCTGGTCTCTATTGGTGAGTCT CTTTATATTTATTATGTATGTATATACGGATTCATTCACTCACTCATTTTTCACTGATTC ATTCTTTCATTCTACACGTGCTTAGAACAGCTTTCTCATCTATCACTTCAACTTCTGCTT TGATCCTTTCATAACTCTCACAATTACCTGACAGCCATTTCTTTCCTTTTCACTTATATT GATTTGTCCTCTCTCTAGAAAGTCATCTTTCTGACCACAGTTTCACATCCTTCTTGCTCT TTAATCTCCCAAACTCAGAAAAGTTATGGTAATTCACTGCTTTGGTATGCATAAATAAAT GTATTGATTTCTTTAAAGTAATTATTCTATCATAGGGACTGTTCTGCACAGAACCTAGAT TGTTCTGGTGGAGCTAATATTTATTGCATAGTTTTTTAATATAATGTCAAATACTATGAC AATTTGTAATTTCTCACTAAGTGAAAACACTGAGGATTCTGAAATCAGTATTTGAAGTGA GGCATGGCCATCAGCAATTATAGGTCTTTTATGTCTGGGAACAAGTTCAAGAGTTTTCAT TTTGCTCGTGAAGGACTGTCAATGTTGTCTTCAAGGTACTCTTCCCAGGCTGACCTTCAG TGGCTAACTTATCCTTCCCAGTAGGCTGCCCTGTATCTGATAACCTTGTACATTTGTCAG CACAGAACTCAAAATCCATGTATCTTTTTCCCCAAAACAGGCAAACAGCTCTGCAAATCA GTTGTGCTTTCCCAATTGGAGCAAGTAGAGAAACTTTCAACACAAAGAATAAGCTTACTG CAAGGTGAGCTCTAAGAAGC bcftools-1.21/test/csq/ENST00000518414-ENST00000521270/ENST00000518414-ENST00000521270.fa.fai000066400000000000000000000000211467060157400251460ustar00rootroot000000000000008 11420 19 60 61 bcftools-1.21/test/csq/ENST00000518414-ENST00000521270/ENST00000518414-ENST00000521270.gff000066400000000000000000000052111467060157400245720ustar00rootroot000000000000008 ensembl_havana gene -264 14941 . + . ID=gene:ENSG00000172748;Name=ZNF596;biotype=protein_coding;description=zinc finger protein 596 [Source:HGNC Symbol%3BAcc:27268];gene_id=ENSG00000172748;logic_name=ensembl_havana_gene;version=8 8 ensembl_havana transcript 21 11400 . + . ID=transcript:ENST00000518414;Parent=gene:ENSG00000172748;Name=ZNF596-005;biotype=protein_coding;havana_transcript=OTTHUMT00000376344;havana_version=1;transcript_id=ENST00000518414;version=1 8 havana exon 21 293 . + . Parent=transcript:ENST00000518414;Name=ENSE00002131504;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002131504;rank=1;version=1 8 havana exon 8423 8506 . + . Parent=transcript:ENST00000518414;Name=ENSE00003704980;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003704980;rank=2;version=1 8 havana CDS 8495 8506 . + 0 ID=CDS:ENSP00000430552;Parent=transcript:ENST00000518414;protein_id=ENSP00000430552 8 havana exon 10486 10612 . + . Parent=transcript:ENST00000518414;Name=ENSE00003704827;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003704827;rank=3;version=1 8 havana CDS 10486 10612 . + 0 ID=CDS:ENSP00000430552;Parent=transcript:ENST00000518414;protein_id=ENSP00000430552 8 havana exon 11321 11400 . + . Parent=transcript:ENST00000518414;Name=ENSE00002123703;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002123703;rank=4;version=1 8 havana CDS 11321 11400 . + 2 ID=CDS:ENSP00000430552;Parent=transcript:ENST00000518414;protein_id=ENSP00000430552 8 ensembl_havana transcript 41 10604 . + . ID=transcript:ENST00000521270;Parent=gene:ENSG00000172748;Name=ZNF596-007;biotype=protein_coding;havana_transcript=OTTHUMT00000376345;havana_version=1;transcript_id=ENST00000521270;version=1 8 havana exon 41 223 . + . Parent=transcript:ENST00000521270;Name=ENSE00002106240;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002106240;rank=1;version=1 8 havana exon 7901 8095 . + . Parent=transcript:ENST00000521270;Name=ENSE00002111129;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002111129;rank=2;version=1 8 havana exon 8423 8506 . + . Parent=transcript:ENST00000521270;Name=ENSE00003704980;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003704980;rank=3;version=1 8 havana CDS 8495 8506 . + 0 ID=CDS:ENSP00000429386;Parent=transcript:ENST00000521270;protein_id=ENSP00000429386 8 havana exon 10486 10604 . + . Parent=transcript:ENST00000521270;Name=ENSE00002132143;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002132143;rank=4;version=1 8 havana CDS 10486 10604 . + 0 ID=CDS:ENSP00000429386;Parent=transcript:ENST00000521270;protein_id=ENSP00000429386 bcftools-1.21/test/csq/ENST00000518414-ENST00000521270/valgrind.txt000066400000000000000000000003561467060157400230320ustar00rootroot0000000000000010599 T C . 10599 T C synonymous|ZNF596|ENST00000518414|protein_coding|+|42H|10599T>C,synonymous|ZNF596|ENST00000521270|protein_coding|+|42H|10599T>C 10605 C G . 10605 C G synonymous|ZNF596|ENST00000518414|protein_coding|+|44V|10605C>G bcftools-1.21/test/csq/ENST00000518414-ENST00000521270/valgrind.vcf000066400000000000000000000006661467060157400227750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 8 10599 . T C . . type=ENST00000518414-ENST00000521270:193000-T-C 8 10605 . C G . . type=ENST00000518414-ENST00000521270:193006-C-G bcftools-1.21/test/csq/ENST00000518414/000077500000000000000000000000001467060157400166475ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000518414/ENST00000518414.fa000066400000000000000000000265561467060157400210150ustar00rootroot00000000000000>8 8:182402-193821 CGAGGTCCGCTCGGGTGAGTGCCCTCCGCTTTTTGTGGCCAAACCCAGCCACGCAGTTCC CTTCCTGCGGCGTCCTCCACACCCGGGGTCTGCTGGTCTCCGCGGATGTCACAGGCTCGG CAACCGCCCTCCTGTCGGCGGGGAGTCCCGCGACGCCCGGAAATGCTCCGAAGCCTGTCG CCCAGCTGCCAGATCTGCGTCTGTGTCCGGTTCCGTCACTGAGGTCGCCCCTGTCCGGCC CTTCCACCCTAGTTCTCTTCACCGTCCGCCCATCCTATCGCGCGCGGCCTCAGGTCCCGA TTCGGCATGTGGCTTGTCTTCCATCGTCCCCACCCTCGCCCCTCTTGGCCCCTCAGGGCA GCCCTGGGATTCGGCAGACGCCAGTCCTCCCTGAGATGCTTCCCCATCCTTCCCTCCGCC AGGCCCTACGTCTCCGCAAACCCCACGCTTCGGGGTGGCCGCCTCAGACAGGACCCTGAG TCCGAGACTGGGGTAGGGGACCTGCCCGATCCTGTAACAACCCTCGTGCTTCTGCACAAT CGCCTCCCACTAGCGGTGACTGTTGGGTGTTTACCTTCCCGGTGTCCCACTGAGAAGCGG GCTCTTCCTTGGCAGGGGCTTCTTCATTGCCTCGCTGTGGATGTCGAGGTGGGGCAGGAG AGTGAGGAGAAAACAGAGGAGGGAGGTAGAGCCAACGAGCGAGAAAAGGGGAGGGAAGTT TAGATGGGAAGTGGATGGGTCTGAGGAATTTGAACAAACACCGACAATGAAGGAGAGTGA CCTGAGCAAGTAGTAGTGGGGTAAATGGAAATAGACAAAATGGGAATCAGCAGAGATATG GAGGACAGAATACAATGAGGAGGCCTTGACCGTCAGTAGCAGAGAGGGCAGCAGAAGCCT AATTCCCAAATTCTTTAGATGGTTTTCTGATTTCCAAATTAGTTTCCCTTTTAAATTTAT TGTGTCAGGTTCAGCTTATGAGGCCTCAATACTTTTCAGTCTTAATTGTATATTGAAAAT ACTTTTTGTTTACTAAATGCTTTTTACATTAATTCAGTGTGCACTTCGTAAGGATAATGA TGATTTGAGTTAGTTTAGTATTCAACAGCTTCCTCTATTCCTTTATATGATCTCTGTATT TAATGGCTGTGGCATAAAGTTTCCAACTAAGTTTAAGTATCAAGTTTTCTTTGTGCTGTT TTCTGCAAATATTGAAGGATGACCTGGATTGTCCTAGAACTTTGTTCCAACAGATTACAT GTGTTCATAATGAATAGACTGCTCAAAGATATTTCCAAAGCTCACCTTTTATGTTTTTCA GTTCCAATAATTACATCTTTTTAAGGTTTATATTTTTTGATGACTTAATGTGATGTTCTG GAGAAGACAAATGCTTTTAATCAATATGATTAAAACCGTGAAAGACAAATCGCTGTTACT TAAGAGTGTGACATATGATCTGAAATCTTTAGGGGGCAGGGATGTTAAGGGAAAACTGCC ACTATCGTATTAAGGTCATGCCATTCCTGTGAAGCTGGTGCTTGTTACTCTCTACTGGCT TCTGTTCACCTTTCCACCGGCCCCAAGACACACACATAGTGACACAAGGCAGTGGACAGG GAAAGAGCAAGACTTTATAAAGTAAGCACACAACAAAGGTATCTTTCTAATGAGGAGGAG GTGTTGGTTCTGGGAAGGAAGCTTGGGATTTGGGTATTCAGGATCCAGAAGTGAGAGAGC CTGGGAAGTTCAGGAACCAGAGAAAGAAAAAGCCTTGCCCATTCTCACCCATGACACTGT GCTCAGCAGGTACTAGCAGACTTCAGGCTCTGTGACTAAAAGGGGTCAGACCAGTTGATA TACCCACAGCTGCCATGTAAGGATGTGTGTGGACTTCACTAGGGAAGAACGGTGTTATGA AAGAAGGGGCAGAAAAACTCACCTGTTGGTCTGCATGTAGAGGTTTATTGTCCTGAATTC CTGGAGGTTCAGTGAAAAGCAGAAGATTGTCTTTTACACATGTTGAGTTATGCCCCCATA TATGTGGTTGTGGTAAAGAAAGAGGGTGTGTTGATGAGAGGTCCTGAAATGCATTTTCCT AATACTCAGCAGGGGCTTCTCAAGAAGGATCTTCCCTAAGAAAGAAGCTCAGAGAACAAA AATGGAAAAGGATTAGATATGGCACTTTCACTGGAAAAAGTCATGTTATTCATTGATTGT TTTGTCATCTCCCGCCTTAAGTGTTGTTTTTAGGATGTGGTAATCTCTGACCCTGCCTAA CACATTTCCCAACTCACCCATAGCCTTCCCTTAACGTCCTCCCATCTTCACGCTATCACA CTGTGACCCAGTGAATTCGAACTTGTGAAGTTCCATTCGGGGGATCATATGGGAAGGGCT TCACACCCAGACATAGATTATAGATGGGAAGTGGGCCACATGGTGTCAGTGAGGCAAGTA TGGGTCGTTTAGGGACAATGCACTGTCAGATCTTTGTTGACCATGATTAGAGAAACTGTG CATATTAGTAGTGAATTAATGTCAGGAATATCTGACAAATCCTGGAAAAGAAGATTGATG AGAGGAAATGTGTTCTGCCCAACTGTATAATGCATTTGAAGCTTAAAACAATGAATCAGT ATTGATCTGGCCACAAAATATTAATGATTTGAATTAAAAAGAAAAGTTTAGAAAATGATA GCTTTGACAAATTAAGGTAGCATTTCATCCACACGATGGAGTGTGTTTTATTCAGTAATT GATTTAAAAATGGAATCAACCTAAGTGTCTAACAGGAGGGAGTTTTATAAATTGTTCACA GAACATCTGTTCCAAGGAGACCTTGATGTTCATAGATTTGTAAAGAATGCTGCTTACTAG CACACTGACTGCTCTGCAAATGTCTGAGGGTTCCTCCACTTGGGGCAAGTTGGGGGTTTG ATCGCAGAGTAAATAAATGGTGCATTTTATAATGTAATATATTCTAGCAAGATGCAGCCC ACAAACTGTATAGATACTCTTATGTACCACATAAAGTTCATCTACTACTTTAACCAGAAC TTGATACTGTATGTATGTTTTTTTTTTTTAGATTTGGATAAAATGACAACTCATTGTTAT TTCCAGTTCACAAAGTAATTGTGAGGCTGAATAAATTTTATTATTTTATAGACATATGTG TAAAATGAATTTTTCTATGAAACTCATTTTTGATGTATATTAGATGCTATTTTATATTCT GTAGTTTAATTATATGTACGCACACACAAACACACACTTCGGTGTCTTATTATGTTTCTG CAGTGAAACCAAAATCCTTCCTTCACGCCCTTTGATTTTATGTTTTCCTCAGGAAGGCAG GAGCTATTGTATATGATAAAATATTATGTTTTATTCAGTCCACTTATGAAATTGTTTAAT ATTGTTATAAATATTTATATGACTTATTTTAAATTTCCAAATAACATAGGTTACATGAAA TTTGACAACTTTATTTTTTTCTTTTCACAACTATTTTGACTGTATACTCACCAAAAATCA AAATTTAGACAAAATTGACTTTTAGACTAATTCTCATTTTTTACATGTAAAAGACCACAT GGGACTTTTAAGTCTAGGTTGCCCTGAGTCTACAGTCACTGAGGTTTTATGTCACTATGT CCTCCATTCTAATAATAGGATTTTCAGGCTTTATTCATGTCATTTTTATATCCTCATTAA GTTTTAAAATTTATTTACATGGGTCTACAAATTTATTTCAAATCGTAGTCATAATATTTG CCTGTTGTAAATAGACACTGATTTTGTGTGTTTGCTTTTTTTAAGGACTAATGTTGCTAA ACAGGAAATATTGATTTCAGAATATTCATAATAGTTTTGCCCACTTTTTAAATATTCTTA TTAGTATTGATAATTAGAATTGATTCCACTTTTTCAAGTTTACAGTCACGTCATCTGAGA ATAACTACAGTTGCAGCTCTTTGACTCCATTTTTGTAGTCCCTCTCCTTTTCCCTCTTGT TTTGGTCCCACCTCAGGCATCATGTGCAGTGGTGAATGGCATCAGCCTCACCCAGCCTCC TTTTTCCAGCCTTACCTTTAGTGGAAATGGTTCTTTTGTTAACTGCTGAATATATTGTTG AGATTTTATTGATTAAGAAGAATTAGTCCCCACAATTTGGTATGATTTTTAAAGATTTTA TATTATTTTTAAAGATTTAAATTATATGAAAATGTTTTTTCAAAGGTCTATTAATGTGAT TTTTTTAATCTTTAAAATTACTTTGTGAAAATGATAGGTTTTCTAGTATGGAATTATCCT TTTATTATTGCAATAAACTCCACTTTACCATGCTCTGTCATTATTTAACCATACCAGTGA TGGCCAGGTGGCCAAAATAAATAGCCAAATGGCTAAAATTGTATTGATGATTTTTGCAAA TGTAAGTAAGGAAAATTGTTGGTTAAATTTGTAGTTATTGTTACATTCATGTTCATTTTG ATTAGCATAATAAACTAATGAGGACAGGCTTATTTTTCTCCTTCAAAATAACTTAGGTTA CAAAGGAACTAGAAGTGATTTCACATGTAAGAACTCTCACAAATCACTTTTACAGTTAAA CTCTGATATATAACTTAAACATTAAAATTGGCTAATCAGATTTTTGTGCTGATTAATGAG GGAAAGTTTTTACTCTTTTTGTGGAAAGTAATATACATATTCATGTTGGAATATAATTAT TCCCATTTCTTAGATTTTAAATTACTACTTTTAAATAAATACAGTCTCTTTTATTAACCT GTGTTTTTTCTTTCCACCGTGGGTCTTTTCAGTTTCATGATTTTGCTCTCAAAACTTTTT AATTATTGATTTCTGTCAAATCTGTTCATTCATTACATTATTTTATTATTTATTAAATTG TTTTATCTTTTTAAGTCTTATTAATATGTACTGAATTTGTAACAATTTGGAAAGTCAAGT AACTCCTGTTTTATCTTTTTCTTGGTTTATGAGTGTTTTTAAAGTTTTACGTTTCTTGAA GATCACAGCTGTAGCCCCAATTCCATGGTTCTGGCTACTTACATTTATCATACTTATTAA TATCATGAATGTAATTGGAATACCCCTTTGATTTTACTGGTGACGTATACCCACTAGTGT ACTGAGACGGAAAAAAAAGTCTTTAGAACTCAGATAAATATACAGTTCATATTTACTATT TATGTATGTGTGATCTCATTATTAAATTACTCTATCATGTTTGTGGAATTAGCAGTTTCT CTTTGAATTTGGATGTTTCTAGTTATGTGTATTTCCAACGTATGTTTTTAGCCACATACA CTTTATTGAATATCATATTTGGTGTTTAATTTTTGCTAGGATTATAGGCTGGACTCCAGA TCCAAACTTGACATGTAGCAGACCCATTAAAAACATACATTAAGCCCCTAGCACTGTTTT AATCTCCATGGCCTGGCTGAGCTTCTGCCATCTGTCTTCCTAGGCACCATGAGGTCTGGA CATCTCATTTGGCATAACTCAGCTGTGGCCATTGGTGGATCTCATCCTTAGTACTAGTCC CTGCTGGCAGGGGTGACCCAGGCCCACATAAGCCATTGCTGGCCTCCTTGGAGGACTTAG AGAATCCTGAGATTGCCCATGAGGATGGACATGCCTTTCAGTCTAGCACCCACCTTTAGT GATGCCTGTGGAGATTGAGAAGCTCACAGGGGCCTTGGATGTCTTTCTTATACCTCCATT GTCTGCAGCGTGACTCCCATACTCTTGAGCCAAGGTAGAGAATTTTTAGGAGGCTTGTGT GGAGGTTTATGGTGGCCCCCATGGTTCTGTGAGACTGGTAGAAAGCACAGACCCCTTAGA CTTCTCCCCAAGGAGAATACGTGAGACTAGTGGAGGAAAGGAGAGTAATGAAATATGCAT TTCGTGTCCCAGGCTATCAGAGCACAGCTCTAAGGAAAAATACAGGGCATCGTATAGCAA CTGGCACAGCTCTGTGAGACTGGGAGATATTGCACAACCTTGAAAAATCAAGATGTGACC CTACTGAATGAACAAAATAAATCTCCAATAATTGACCATAAAGAAATACAGGTTTCTGGC TGGGTGCGGTGGCTCACACTTGTAATCACAGCACTTTGAGAGGCCGAGGTAGGCAGATCA TTTGAGGCCAGGAGTTCAAAATCAGCTTTGCCAACATGGTGAAATACAAAAAAAAAAAAA AAAAAAAAAAAAAAAATTAGCTGGTCGTGGTGACGGGCACCTATAATCCCAGCTACTCAG GAGGCTGAGGCAGGAGAATCACTTGAATCCAGGAGGTGGAGGTTGCAGTGAGCTGGTATC GTGCCGTTGCACTACAGCCTGGGCAACGCGAGTGAAACTCCGCTTTAAAAAAAAGAAAAA GAAATGGAGGTTTCTGATTTTCCTGATAAGAATTACAGGTAATTGCCTTAAAGGAGGTCA ATGAGCTATGAGACAACACTGATAACAAGTAAAATCTGGAAAAGGATACATGAACAACAT GAGAATATCAACAAAGAAAAACCATAATAAAAGAATCAAATATAGATTCTGGGGCTGAAG AATACAGTAACTGAACTGGATCAATACAAGGCTTCAAGAGCTGACTTGATCAAGCAGAAG AAAGAACCAGTGAACTCAAAGACAGGTTATTTGAAATTATTCAATCAGAAGAGCAAGTAG AAAAAGAATTTTTTAAAAGTGAAGAAACTGTCTGTCTTTGCTAAAAATTGGAGGGTCCTA AGAACTCCTCCCCGCCCCCACTGCCAATGCAGAGTCTTACTCTGTCACCCAGGCTGGAGT GCAGTGGTTCGATCTCCGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCATA CCTCAGCCTCCCGAATAGCTGAGATTACAGGTGCCTGCCACCATGCCCAGCTAATTTTTG TATTTTTAGTAGAAACGGGGTTTTGGGGTTTCACCAAGTTGGCCAGGCTGGTTTTGAACT TCTGACCTCAGGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAG CCACCATGCCCGGCAAGAACTCCTTTTTATGTTAGATTCACTAGGGTTTAGCAGCTCACA GAACCCAGGAAAACAGTTTACTTAGCTGATTTATTACAAAGGACATTTTAAATATTACAT ATGAACAGCCAGCTAAAGAGTTACATACAGCAAGTTTTGGAAGCATCTTAGGTTTAGGAG GTCTGTCTCCAAGCAGTTGGGGGGTACCATTGTTTCAGCATATGGATGTGTTCTTCACCC ACCCAGAAGCTCTAGGAATCCCATCATTCAGGGATTTTTATGTGGTGTTCATCAAGTAGG CATAATTGTTATTAACTCGATCTCCAGCCTCTGTCCCTTTCCCAAAGGATAGGGGGTGGG ACTGTACGTTCCAAGCTTCTGATCAAGTCATGGTCTTTCAGGTGATCACCCCCCATCCTA GAGCCTAGTAATAATTGTCTCATTAGAACAGAAGACACTCTTATCACCTATGAAGTTCCA AGGCATTACGAGCTCTGTACTGGGAACCAGGGTCAAAGACCAAAAAGAACAAAAGCTTCT CCTAGCAACTCTGTTGCTTAGGAAATTACAAGGGTTTTGGGTGGCTCTGTGCCAGGAACT GGGGATGAAAACCAAACTATCTATTTCTTACAACTAACAATGTCACATACATGTTCAAGT TTTCATGTTCTTAGTGTCCTTTCATTTCAACTTGAGGAACTCCCTTTAGCATTTCTTGTA AGGTATGTCACTTGTAAAGTGTGTCTTTTAAGGAATCCACCATGATAAAATGAAATTTGA AGCTGCTTGGTAGATAAATTCATGCTACATTTATCTACAGGTCAGACTTGAGGGACTGGT ATTTCTAGAAGCCTCACATGGAAGAGACAGAATCATTCAGTACAAGTGTATCCAGAGGAC CAGCAGAAGGGAGAAGGAATGGAGGGAGGCTCCTGAGGGCTGAGATGCATGTGGAGAAAG CCTGCAAGCACACAAACCGAGAATAATTAAATCTGAGAAATTCCAGGATTTATCTGTAGG TGGAGCCACATCTCCATGATTCAGGGATTCTTAGGATTTGGAATCATAGAAGGAATTAAA CATTTCAGAATTCCATGCGCTAGGTGGCATATGAAACTCCATGATTTTCACATTTCTAGG TCTAAAATAAAAATATTTATATCTTTATTAGCAGCAATAGTCATTTCTTCTGACCCTGGG AGAGGAGAGCCACCAACCCAACCCACCCCCTACCCACTGCATGTCCTTGTTGGTTGGACT GGGGCTAATAGCTTTGGGGCAGATGTTAGAAGCAAAACTGGAGTGTCATGGTTTTTTTGT TTTTGTTTTTGTTTTTGCTCAGATTTGTCTTCTTAGTGCTTGGATGGTGTGAGTGAAAAC CCAGAGGAATACATTTGGTGGCTGAGCTAGTACAATGCCATCACCGGTGAGTGGGAAATT CTTCTTTCTACTGAAATTTGTACCCCTGTTACCAGCCTAAGGGCAGATTCATCCTATTAA CATGGATGTTCTAAGTGCACTCAAGGATCCAAGCTCCAATTAAGATTCCCCAGGGCTTCG GAATGTTTACATTGGCTCAAAGAGTCATCAAGAAGTAATGTCCTTTCAACAGTACACTAA GGCATTCCAGCCTCTACTAAGGCTGTGTATTAAGATGTGAGAGGTTTTTGTTTCTCTCAT CCAGTCTCAGGGAAATCATTCATTACGAGCCTCTCATGGCCTTGTTGGGGAAATAAATTC ACTCATTACCTATGTTATTGGCAGGAGTGGGCTTGAGAGTATATGTGGGTAGGTGGTGAA AATAAGTGAGAGCAGGTTATAGCCCATACAAAGGCAAGCTCAGTTAGTCTAGTGTTTCAG GTGTTAGGGGAGGGCTGTTTAACTTGAAGGGAAAGCAGATAGGGTTAGGACAGAGGAGAC AATGAGGAATTATTCATTTATTTTTCCTATCTCAAAATCTTAATGTCTTGAGAGAATAAA TGTGAACTTTTGAAAAACTTAAAAAGCAAAATTAAAATTCTTATTACCCTTGTCCCCAAA TTAACCTCTGATCAAATTTGATAACTGGAAGCAACTGGAGTGTTGTTTCTTTAATTTTGG TTGTGCATTAAGTGATGGAGTATAGGAAACAGAGTAAATTTAAAACTCTGAGGAAATTTT TGAAGTGGAGAGACCAGGACAATCAAAGGATTTTTTTTCCCCTAAATCTAGAGACAACAT GAAGAAACAAAATAGAATAGTACCTAGTGCATTAGTCCATTTTCACACCGCTATAAAAAA CTACCTGATAGTGGGTAATTTATGAAGAAAAGAAGTTTAACTGACTGACAGTTCTGCAGG CTTAACAGGAAGCATGACTGGGAGGCCTCCAGAAACTTACAATCATGGTGGAAGGGGAAG CAAGCACCTTCTTCATAAGGCAGCAGGAGAGAGACCAAATCAGGAAATGCCACACACTGT TAAATCATCAGATCTTCTGAGATATTACTAGCATGAGAACAGCAAGGGGGAAGTTCACCC CCATGATTCAATCACCTCCCACCGGACCCCTCCCCCAACATGTGGGGATTACAATTCAAG ATGAGATTTGGGTGGGGACACAGAGCCAAACTATATCACCTGGTGTTTGAAGATCCCACA TAAAATTGAGAAAGGAAATCCTCAGACCATGGAAAGTGGCAGGATGAGACCATCTTTCAG TACTGAAGTCTTAGAGTCCCTGGCTTGTGCTGCTGAGCCATTCATCCTTATCCATTAACA GTGAACACCTGAGTTGTGTAGACATAAGAGGCTGCATCTGCTGATACCAAGTTCTATATG AAAGTTGTTCACACAACTGAGTGTTCTCAGTCATTTCATGAATAATGTATTTGTGGCTTG TATCTAAAAAGTGATAGATAGGAACCACTTTACATACTATCTCATTGGACCTTTTTGAAC TCATAACAGGTCTTTATTTTATTCTGAGGACACTGAGGTCCTATAGTGGAATATCTAACT ATAGTCTTGATTAAAACGTGACAAATTATGGATGCTGCCTCCCTTGTAGTGAGTCTATAG ATTTTCTTGAAGGTGGTGGAGAGGAGAATTTTAGTTCTAAATTTCCAAGTACAGATTTCA TAATTAGTATCTGTAAGTTATACTTTAGAAGTCTATTGGGAAATCTTCAGGTTATATTAT GCCACACCACATGTGATATTTCTCTATGTGAAGTTTTATGTATGAGTAAATCTGAAAGCC AGATTCCCAGTTCAGATTTAAAGCAATGTGACAGGAACCCCAAACACTGTTTTGAGTTTT CTGTTCATACCACCCACACTTCCTTAGTACAGTCACTTTGATCTTGCTCCACTGAACATT GGCAGAGATAGCCCTGTTTGCAGTAGAATGTCCATAATGTTTTAGGATTCCATGACCTTC GAGGATATCATTGTAGACTTCACTCAAGAAGAGTGGGCCCTGCTGGACACATCCCAGAGA AAGCTGTTTCAAGATGTGATGTTGGAGAACATCAGTCATCTGGTCTCTATTGGTGAGTCT CTTTATATTTATTATGTATGTATATACGGATTCATTCACTCACTCATTTTTCACTGATTC ATTCTTTCATTCTACACGTGCTTAGAACAGCTTTCTCATCTATCACTTCAACTTCTGCTT TGATCCTTTCATAACTCTCACAATTACCTGACAGCCATTTCTTTCCTTTTCACTTATATT GATTTGTCCTCTCTCTAGAAAGTCATCTTTCTGACCACAGTTTCACATCCTTCTTGCTCT TTAATCTCCCAAACTCAGAAAAGTTATGGTAATTCACTGCTTTGGTATGCATAAATAAAT GTATTGATTTCTTTAAAGTAATTATTCTATCATAGGGACTGTTCTGCACAGAACCTAGAT TGTTCTGGTGGAGCTAATATTTATTGCATAGTTTTTTAATATAATGTCAAATACTATGAC AATTTGTAATTTCTCACTAAGTGAAAACACTGAGGATTCTGAAATCAGTATTTGAAGTGA GGCATGGCCATCAGCAATTATAGGTCTTTTATGTCTGGGAACAAGTTCAAGAGTTTTCAT TTTGCTCGTGAAGGACTGTCAATGTTGTCTTCAAGGTACTCTTCCCAGGCTGACCTTCAG TGGCTAACTTATCCTTCCCAGTAGGCTGCCCTGTATCTGATAACCTTGTACATTTGTCAG CACAGAACTCAAAATCCATGTATCTTTTTCCCCAAAACAGGCAAACAGCTCTGCAAATCA GTTGTGCTTTCCCAATTGGAGCAAGTAGAGAAACTTTCAACACAAAGAATAAGCTTACTG CAAGGTGAGCTCTAAGAAGC bcftools-1.21/test/csq/ENST00000518414/ENST00000518414.fa.fai000066400000000000000000000000211467060157400215260ustar00rootroot000000000000008 11420 19 60 61 bcftools-1.21/test/csq/ENST00000518414/ENST00000518414.gff000066400000000000000000000032031467060157400211510ustar00rootroot000000000000008 ensembl_havana gene -264 14941 . + . ID=gene:ENSG00000172748;Name=ZNF596;biotype=protein_coding;description=zinc finger protein 596 [Source:HGNC Symbol%3BAcc:27268];gene_id=ENSG00000172748;logic_name=ensembl_havana_gene;version=8 8 ensembl_havana transcript 21 11400 . + . ID=transcript:ENST00000518414;Parent=gene:ENSG00000172748;Name=ZNF596-005;biotype=protein_coding;havana_transcript=OTTHUMT00000376344;havana_version=1;transcript_id=ENST00000518414;version=1 8 havana exon 21 293 . + . Parent=transcript:ENST00000518414;Name=ENSE00002131504;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002131504;rank=1;version=1 8 havana five_prime_UTR 21 293 . + . Parent=transcript:ENST00000518414 8 havana five_prime_UTR 8423 8494 . + . Parent=transcript:ENST00000518414 8 havana exon 8423 8506 . + . Parent=transcript:ENST00000518414;Name=ENSE00003704980;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003704980;rank=2;version=1 8 havana CDS 8495 8506 . + 0 ID=CDS:ENSP00000430552;Parent=transcript:ENST00000518414;protein_id=ENSP00000430552 8 havana exon 10486 10612 . + . Parent=transcript:ENST00000518414;Name=ENSE00003704827;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003704827;rank=3;version=1 8 havana CDS 10486 10612 . + 0 ID=CDS:ENSP00000430552;Parent=transcript:ENST00000518414;protein_id=ENSP00000430552 8 havana exon 11321 11400 . + . Parent=transcript:ENST00000518414;Name=ENSE00002123703;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002123703;rank=4;version=1 8 havana CDS 11321 11400 . + 2 ID=CDS:ENSP00000430552;Parent=transcript:ENST00000518414;protein_id=ENSP00000430552 bcftools-1.21/test/csq/ENST00000518414/ascii-art.txt000066400000000000000000000003321467060157400212620ustar00rootroot00000000000000 eeeeeeeee|iiiiiiiiii CACAAAGAATAAGCTTACTG|CAAGGTGAGCTCTAAGAAGC A---|-----------CTAAGAAGC .. this one is called ACT-|-------------AAGAAGC .. but also this one is possible bcftools-1.21/test/csq/ENST00000518414/incorrect-inframe-del.txt000066400000000000000000000002671467060157400235660ustar00rootroot0000000000000011397 ACTGCAAGGTGAGCT A stop_lost&inframe_deletion|ZNF596|ENST00000518414|protein_coding|+ 11397 ACTGCAAGGTGAGCT A stop_lost&inframe_deletion|ZNF596|ENST00000518414|protein_coding|+ bcftools-1.21/test/csq/ENST00000518414/incorrect-inframe-del.vcf000066400000000000000000000007071467060157400235240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 8 11397 . ACTGCAAGGTGAGCT A . . type=ENST00000518414:193798-ACTGCAAGGTGAGCT-A;EXP=stop_lost&inframe_deletion|ZNF596|ENST00000518414|protein_coding|+ bcftools-1.21/test/csq/ENST00000519442/000077500000000000000000000000001467060157400166515ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000519442/ENST00000519442.fa000066400000000000000000001330501467060157400210050ustar00rootroot00000000000000>5 5:157052667-157098508 AACAGAAAACATCCAACAAGAACAATTTTATCTATGTTTATTTAATTACAACAAAGAACG ATGTATGCCAAATGGAAAAAAAATATTTTAAAATGATAAAAATATTTAGAAACAGAAATG ACTAAATTTAGCTGAAGAATCACCCAGGTGCCATTAAAACACATTTGGAACTTATAATTG GTTATTAGTGTAAGTTAAATTTAGCAACCAAGTCCAAGTTCACTAGGAGTTGTCAAAATA CTTTCAAAATGTTACATCAAAAATTGACAACATCCATAAGTATTACATAAAAAGCAAACA AAAAATCATTTAAAAAATGTATCCTGAGATAAAATAAAAATCACACTATGCTAGATTTAT TTCCCCTTTCCCCTCACATACAACTGTGAGGCTTCAGTATTTTGCATGTTCCAGGATAAA GTAATAATAATACATGTTGATGCAAATTTCAGCCATTAAAATTAAACTACTTAATAACTT AAATATTCCTACAATGAAACATCCAGACTCTAGTTTCACTAATCAAAATTTTATGAAGAC ATAAATTGCATTTGGTTTTAACTCCTCAAATCACGACTGAAAACTTTCAACAAAGAATTC TAGGCTTTTTTTTTTCTCATACCAACTGACCCAGAATATATTTTAAGAAATGTTTATTTT CTGTGCATATTTGTTTTAAAATTATAAATCCCTGAGCACTTTTTCTTCTTCCTCCTCATC ACTGTCGGTGACATTGACTTGCTGGATGCTAGAAGGAGTTGATGTCGGGGCTGTGAAGAC ATTCTCCAAGGTTCCAATGTCCAGCTGAGGCACAGGGTTTAAGTTTTCTTCCCCACTGTG GCTATGACTGTTATAGTAAGAAGTTCCATTCATGTTCTCACAACTCCGAGAATTTTCACT GTGTGTGCATTCACTTGAGTAGTCTCTAAAAGAATAGTCTCTATTTAAAGTTGAAAAGAT ACCCTCATGTTTTGGGTACCTGTCTTCATAATAACTAAGGCATTCTGGCATTGAACTCGG AAAATTTCCATAGCCAAAGGGAGGCCGACTGTAAGGGCATGTACTGCAGCAGAAAAACAC AAACAAGGAATTAGATCTTGCCCACATATTGCCTTGCATACAGACTAACAGAGCAAGTTA ATGCCTCCTCTTTGGGGTTTGGAAAGTTCCTTTCTGCAAACACTTCATGTATTCCTCTGC TCTTTTCCCACTGCCCAGTCCCCACCCACAAGGAACAGGAAAGGGAGCTTGTGACTGGAA TACTCACCAGCACTATTATCTATCGTTAGCCTCAGGCTTCTTACCTTTGACAACCATGAT AACAAAATTGCTTATTCTGGTCTTTCTCTCATGATGCCTCATACCATATAAGGTTTTGGA AATGCAGATGTGTGTTGAGCTATGCTAAGAATTGACACTCAGTGGTTGGGCGCGGTGGCT CACGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCGGGCGGAACATGAGGTCAAGAGAT AGAGATCATCCTGGCCAACATAGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGC TGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGGATCG CTTGAACCCAGGAGGTAGAGGTTGCAGTGAGCCGAGACTGCGCCACTGCACTCCAGCCTG GTGACAGAGTGAGACTCCGCCTCCAAAAAAACAAAAACAAACAAAAAAACCCACAGAATT GACACTTAGTAAACAATGCAATAGTGCAATAGTTGTTTTTAGTGGTATTTGAAAGGAAGC TCATGTTGGGGGGGAAATGTATAACTAGATTGAAATCAAGAGATCCAGAATATTGAGGCA CTGGAACAGAAGACAAGTTAAATTTTTTCATTGACATTCAATAATAAAGTAAATTTAAAA CACTGTTACTACTAGAAAGATTTGAAACTGATAGTAAACTATGGTCTTAAAGGTCTTTTC CAAAACATTTTTTGGAGGGCAGGAATGTGAAGAATCAAAAAGACATTTTGCAGTTTTAAA AGTTATGGTTTTTTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGG CCGAGGTGGGCGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAAC CCCATCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCC AGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGAAGGCGGAGCTTGCAGTG AGCCGCGATCACGCCACCACACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAA AAAAAAAAAAGTCAAATCCAAAATTTCTGCCATTTGCTGGGCACAGTAGTGCATGCCTGT AGTCCCAGCTACTCAGGAGGCTGACGCAGGAGGATCGTTTGAGCCCAGGAGTTTGAAGCC AGCCTGGGCAATATAGTGAGACCCCCATCTCAAAAAAAAATTTTTTTAAAAAAGATTATA CCTCAAAAATTCTGCTACTCAAACCCATTTGTCAATTGTTTTTAAGTATTATTCTCTCTT TCAAAGGCATAGAGCAGGAATTATAGGAAGAGGTAGAGTCCAACCATCTAGTGACAGATA ACATAAACATAATGACCATACTCATCGGCAAAACCCATGGCAAGTTAAGTGTTTCATTTC TGGCCTTCACACACACACACACACACACACACACACACACACACACACAGAGTCAACTTT GTTACCTTACTTTTAAAAACCTAAGTATGACAGACATACTAGACTATTATCTCAAACTCT GAAACTATGCCCTACCCCCAAATCTTCAAGTGCTAGGTACCTTGCTCATGTTAATTATAA CAAATGAGGTAAAGTTTCTAAAATTTTTCAGGTTTCCATGCCTACTGCCACTCTTAGTTC GGGCATTTTAAATTTAATACACATGTCCTGAATACACTGTGCTTCTTTTTTTTTTTTTTT TGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCATGAATTTGGCTCACT GCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTACCGAGTAGCTAGGA TTACAGGTGCCCGCCACCATGTCCGGCTAATTTTTGTATTTTAGTAGAGATGGGGTTTCA CCATGTTGGCCAGTCTGGTCTCGAAATTCTGACCTCAGGTGATCCGCCCGCCTCAGCCTC CCAAAGTGCTGGGATTATGAGTGTGAGCCACCGTGCACGGCCAAATACACTGTGCTTCTG GCTAGCACAGCTTTGCTCATATAGCAGGTCTCTCTATCCATTGAATTCCACAGATAATTC AGGGATGAAAAGAGGCTGACTATGGGTACAAACATACAGTTAGATAGAAGATGTAAGTTC TAATGTTCAGTAGCACAGTAGGGTGCCTATAGTTAGCAACAATGTCTGGTGTATTTCAAA GTAGCTATAAGAGAGGACTAAAAATGTTCCCAATATACAGAAATGATAATCAAGGTGACA GATAACCCAAATACCCTGACTTGATCATTACACATTTTATACATATTTATGACAAGTACC CCATAAATACGTAAAATGTTATATATCAATAAAATAAAAATCTATCCCTTCCACAAAGCC TTCATTTCAGCTAGAAATAATTCACCCAACAACTGTCTTTTTCAGGACTCAATGTAGGCA AGACGCTATGTAAGGCTTGGTAGATAATTTTTTAAAAAACATAAAATCTAGGTATATATT AGACATGTGCTAAAGTCTATAACGCCAGCATTATAGTGACTATTTTGGTGTGGTAAAGAC GAGTTCGTGTTATATTCAGAGAACAAAAAGATCAATTAAGACAAAGGCAATCCTAGAAGG TTACATGAGTGAAAGCAAAAAACTATAAAAGCATCATGGTGTAGGGGGAAAAACATTAAT TAGAATAGTCCAAATAATAATATTATCCAATATGTAAGCATTTACTATTTTTTAGGCATT GGCCAAGGAGTGTATATGTTATTTCAATATAACACTGAACAACACTCAGAACGACCCTAA GACACAGACACTATAAATATCTCCACTGTACAGATGAGGAAATGGAGCTTTAAAAAGGTT AAGTAACTCGCTCAAAGTGATATAATTAGTAAGTGGTAGACAGAATCAGGCAATTTGACT CCAGAACTTGTTCTCCTAACTACCATGCCGCCCTACCCAGGCTCTAGTTCTAGCTATGCC ACATAAGAATCTGGTAAACTTAAGTAAATCTTACTTTATCTGATCCTTGTATCCTTCTTA TATAAAATAGGGATAACAATGTCTGTTCTGTCAACCTAAAAGGTCTGTCATAAGGAACAG GAGAATATAAGTGATGGAAACTAGAAACACTATTTCAATGTATGATTGGTAAGTCTTATA AGAAGTTACTGCAATTTTTAGCTTGAGGATTTGTATTTGGTTCTTTTTTAATTTCTATCT CCTTATTGATATGATCTATTTGGTGAAACACTGTTCTCCTGGTTTCCTTTAGTTCTTTGT CCATGGTTTCCTTTAGTTCCTTGAGCATATTTAAAACAGCTGATTTAAACTGTCTATTAA GTCCAATGTCTCAGCTTCCTTGGGGATAGTTACTATTAATATTATTTCCTTGTGAATGCC CTACTTTCTTGTTTCTTTGCATGTCTTGTAACTTTTTTGTTGAAAACTGGATGTTTTGAA TATTATAATGTGATGCCACTAGAAATCAAATTCTTTCCCTTATCCAAGGTTTGTTGTTGT TGCTTGTTTGGGGTTGTAGTTGTTTATTTGGTTTTCTAGAGTATTTTTGTAAAGACCGTA TTCTTTGTTATGCATGGTCATTGAAATCTCTGTTCAATTAGCTTAGCGGTCAGAAATTTG ATAGAGATTTCCTTAAAAACCTAGAAACAAAAACAAAACAAAACATATTTTCCTGGTCTT TACAGATTGGCTTTGAACTGGGGCACTCCTTAAATACTTAGCCAGGCTATTTTCAGTTCT GCCTTAGTCTTTACTTCCTGCTTATACAGAGCCTACAGATCAGTTAGAGTTAAAAGCTTG GGGTCTTTTTGTGTATTTTCTGAACATGGGTCTAGCTCTGGATATGTGTGTGGCCTTCTG GATTTCCCATTTATATATATACATTATATATATATTATATATTTTTATATATATATATAC AATATATATAATTTTATATATATAAAAAATATATAATATCTATATTATATATTATATATA TATACTATATATATTGTATATATATACACTATATATTTTTATATATATACTATATATATT TTTTATATATATACTATATATTTTATATATATATACAATATATATATTTTATATATATAT ATATATATATACACACAATATATGTATTTTATATATGTAATTTAAGAGATGGGGTTTTGC TGTCACCCAGGCCAGAATGCAGTGGTATGATCATAGCTCACTACAGTCTCAAATTCCTGG GCTCAAGCAATCTTCCTGCCTCAGCCTCCCAAGTACCTGAGACTACAGGTACACCACCAC ACCCAGCAACTTCCAGAGACTTGAATGATTGGTTTTTAAAAATAGTTTTCACCACTTACA CTTGTTTGCTAGAGACTGGGTCCACAGAGCTCCCTGTGCTGCCATCTCAAAAATGAACCG TACTCTCACTTACCTTTTTAATTATTTGATTCTATTTCTATTCTTGAGCTTTGCTCTTGG GTGCAGTTAAATTACTTAAAAACAAGTTGGTCCTTTCAGGTCTTGCTTTTAAGAATTTTG AGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACCTTGGGAGGCCGAGGCGTGTGGA TCACCTGAGGTCAGGAGTTTGAGACCACCCTGGTCAACATGGTGAAACCCCGTCTCTACT AAAAATACAAAAATAAGCCGGGCATGGTGGTGCGGCCTGTAGTCCCAGCTACTCCAGAGG CTGAGGGCAGGAGAATTGCTTGCTCGAACCCGGGAGGCTGAGGTTGCAGTGAGCCAAGAT CGTGCCACTGCACTCCAGCCTGGGTAACAGAGTGGGAACTCGTCTCAAAAAAAAAAAAAA AAAAATTAGAGCACAATGGCTCATGCCTGTTAATTCCAGCACTTTGGGAGGCCAGGAGTT TGAAAACAGCCTAGGCAACAAAGTGAGGCCCTGTCTCTACAAAAACATGAGAATATTAGC TGGGCATGGTGGTGCACACCTGTAGTCCCAGTTATTCAGGAGGCTGAGAAAGAAGGATCA CTTAGGCCCAGGAGTTCGAGGCTGCAATGAGCTATGATCATGCCACTGCACTCCAGCCTG GGTGACACAGCAAGACCCACCCCGTAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGA ATTTTTAGTTGTGACCATTGCAACATTTGGGCTAAGGCTATCTGAAGCAAGACCCTTCTG AGTACCCAATGTTCTGTGCCCCATAGAAGTTTTCCAATCTAGTTGGTGGGACTATTCACA GCACTGTGTTAGTGCATGATTGCCAGATATTGTTTTCTCTGATCCTTTCAGGTGGTTCTT TCACTGCCTTGGGTTGTTTCTTCACAAGGATGCACTAATTAGTACTTCACCGAATACTCA AGAGGGACCCTACACAGTCATCTGGAGTTCCCTCTGTGCGTAGCTCTCTTTTCTCTGGTA CTCTATCCTGAAAAGTCTAGCTAATTAGGTCTCATTGGATTTCCAGTAGAGACGGGTGAA ACCCCATCTGTACTAAAAATATAAAATTAGCTGGACGTGGTGGTGGGCACCTGTAATCCC AGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCTGGAGGCAGTGCAGTGAGCC GAGATCGTGGCATTACACTCCAGCCTGGGCAAAAAGAGCGAAACTCCATCTCAAAAAGAA AAAGAAATGTCTGCATCCAGTGGACAGGGTGATTTTAGACTCTGAACCAATGTGTGAAAC ACCTTGGGAATTTTATTTCTAATGAAAATCACATAGAGCCCTGAGTAAAAACAAGATTCT TTCTGTGCTTTACCTGGATCAACGACAAAAATTTTATATTCCTTTTATCAAGGTTAAGAA GTCCTTCCAGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAACACTCTGGGAGGCTAAGG CAGGCAGATCACTTAAGGCCAGGAGTTCAAGACCAGCCTGACTAACATGGCAAAACTCAG TCTCCACTAAAAATACAAAAATTAGCCAGGCATGGTAGCATGTACCTGTAATCCTAGCTA CTCAGGAGGCTGAGGCACGAGAATCGCTTGAACCCCAGAGGCAGAGGCTGCAGAACCCCA GTCTGGCAGACAGAGCAAGACTCTCAAAAAAACAAAAAAAAGAAAAATTCCTTCCAGGGT CTTGGCTTTATAAAGAGGTTTTAGTTTCAGTACCTATCCCCACCTTGAACAGGGGAGCAG AGCAGGGTCAAGACCTCATCTTTTTTCCCTTCACAGACATTAAAACTCAAGTTTAGGGTT TTTTCTGTTTTTGTTTTTGTTTTAGAGACAGGATCACAATTTGTTGCCAAGACTGGCCTC GAACTCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCATGACAGCACATCGAGCT TAAAACCCAAGTTTATAACCAATGAAACTATTTCTGAATCTGAAAATCATCTCCAGGACC ACTACAACTAGTTTTTAACTTGTTGATCATTTTGGCACATGGTGAGTTCCTTGCTGGGGA GTTCAGGTAGGTATTAAATTGTTCATATTTAAATTTAACATTTCTAGGTAGTTACAGCAG AAGGTATTCTATGTTAACTAAGTCTATCATGTTTTGGGACTGTTAGTTTCCCTCCTCCAT AAGTTTAGGCAAAAGTTTGTATATGTATGCAGATATGCATTATTATGGAAGAAGTCCATA ACTTCAATCAAATTCTCAAATGGGTCTCTGACCCAAACAAAGGTTAAAGAGAATTGCTTT TAACCTTTGATTCATTTGCCTAAAATTTTACAATTTAGATGCTATTTCTACAAATCCAGG AATTCTTTGAACTTACTTTCCCTACAATATATCTGAGTGTATTTTCCATATATTTCAAGA TAGTAAATCCCCATTTGTCTTCATATCTTTTCTTTATCCCTACTTACATAGATTTTAAAC ACATTTTTTACCCAATGGCCAACAGAATGAAGATACTATGTATCTCCCTTGAATGTGAAA GCCCAATATACTGCAAGAAGAAGGAAGAGGAAGGGGTAGGGAGAAAAGAACTAGTCTGAA GAATTAATGTAGTACACAGAAAGAGAGCATTTTGACAAACACAATATGATGATGGTTAAG ATCTGAAGGCAGGAATAAGATGTTAGCCCCAGAGAGGGGGAGCAGCACTTCTGAGTGTCC ATCTGTTTTGTAAAATGACTCCTTGATTAAACCACCTAGCCTACTTGATTTTTACTCTAC ATACACAGGGCAAAGTGAACTGCGTAGCGAAAAGAAACACTTTTTGGTTTTTTGAGACAT GGTCTCACTCTGGTGCCCAGGTTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAGCCTT CACCTCCCAGGCTCAAGTGATCCTCCCACCTTAGCTTCCTGAGTAGCTGGGACTACAGGC ACATGCCACCACGACCAGCTAATTAAAAAAATTTTGGGGGTAGAGACAAGGTCTCACTAA ATTGCCCAGGCTGGTCTCAAACTCCTGGGCCCAACAGATTCTCTCTCCTTGGCCTCCCAA AGTGTGTTGGGATTACAGGCGTGAGCCACCACGCCCAGCCAAAATTTTTAATAGTGAATA ATCATAAATATATACATATATACACAAAATATGTATATATAAGTATATCTCAAATGTCCA TTACAATTCTAACATTGAAATAGTTGGAAAATTCCACATATAAATAACTAGAGTAGGAAG GAAATATATATATAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGGGGTGTGATCTTGG TTCACTGCAACCTCTGCCTCCCAAGTTCAAGCGATTCTCCTGCCTCAAGCTCCCGAATAG CTGGGATTACAGGTGCCCACCACCACACTTGGCTAATTTTTGTATTTTTAGTAGAGACAG GGTTTCATCATGTTCACCAGGCTGGTCTCAAACACCTGACCTCAGGTGATCTGCCCGCCT CGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCATCTGCCCAGAAATATTCC TTACAGAAAATTCCATTATCAGTTGGGAGAAGAGAAAAATTGAGAGAGAATCAATTAATT TTGGCATTTAGGGTTTACTGAAATATACTATCTAGACAGTCATAAATAGATTATTTCCTT GGGGAAATTATCATCAGACACATACAGGTAGAGTCAGAAAAACAACTGAAAAATATTATA ATTGATAAGGCTAGTCTTCTTTTCTAAAAAACTATGCATAGCTTAATGTTTATAGTTGAC ATACTGCTCTGACATTCTTAAATGAAATAAAATTCAGTATAATAGCTAGTCACTTCATTT GGTTCTTCCAATAGCATTATTATTAATTAGCAGTAATAGTATTAACAAAAAAGGTAGTTT CTGTCTTCCAAGAACTTACTTTTGGGTGGGAGCAGTGGCTCATGCCTATAATCCCAGTAG TTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAA TATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGATAGGCAC CTGTGGTCCCAGCTACTCGGGAGGCTGAGATAGGAGAATTGCTTGAACCTGGAAGGCAGA GGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCT GTCTCAAAAAAAAAACAAAAACAAAAACAAAGAACTTACTTTCAAGAGCTTCCTTTTAAA ATGTTCCTTAAAGTGTCAGATAATTTATACATTAACAGTCAAATCTTACAAGCCTTGTCC CAAATAAATAAGATAGACTTCTATGATTTAATCTATGTAATATGTAAGGAAAATTACCTG CCCCAATGTCCACTTGACTATGTGAGGTTTTTATTCAAAATATATTTTTTCCATATGATT CTCTGCTAGCAACTAACAGCTGCCAATCAAGAGGAGCTGTCATAAAAGAAGTCTTACTGA TATAGTAAAAAAGACAAATATGAAATTCAAAATCAATCAAACCTGAATTTGACTATTGGC TCTGCCACTGTACAACCTTGATGAGGCTATTTACTAATCCATTTATTTAACTGAAAAAGT AGGGGAATATTATACCCAAGTCACAGGATTGTTATAAAAACTACGTGTAAAAATTCTTAG CTCTCAAAACACTAAAAAGAAGAAAAATGCAACAAACAAAAAAGTAGTAACAGCTAGAGT GAGACTGTGGTACACAGCCCATTGTAATTGACTCTTCTTCACCTATCCTGTGAGTAAATA GGGTCCAAGCATTTCCCATATTACAAAATTAATTATGTAGCAGATACAATTTTCCACAAT TTTTGTTATAGGCCTCAAGATTCTAACTAAGGCCAAGTGTTCTCAAATTTACTCATTCAT TAAATTCAATCTACACCCTTCATATTCTTCTTATATGTAGGAAACATTTTATAAAATTCT CCAAAATTCCTGTAAAATCCTAGATCCTAGCAGATAGCAATGAAAAGAGATTATCAACCT CCCCGGCCTTAAATTAAAAGTCTCTTGAGGTTTGATCCCTTGAACTAAAATACTTATTAA GGCTGCAAAAGATAAAAAGATTCTACATAAAACAAAACAAACCCTAGATGACAAAAATCT TCCTTTCTCCTGATCTAATCCTCTGGTCCCACTTTCTTCCAGTCCTGAGCTAAGGGCCCA AAAGCAAGCAATTGATTATAAATTGAAGCAACATAATATATACCTCAAAAGTTGTTTCTA TTGAGGTGTAGGTATACCCTAATGGGAAGTAGATTTACTTGCTAAGTAAGAAACAATAAA AGATTGGTGTTAGACAGTTTAATACTCCCGTCTCAACAGAAACCATCTTTGTCTACACAT TTAACAGTAATTGAAAAGTAAAGGCTAGGCCGGGAATGGTGGTTCACGCATGTAATCCCA GCACCTTGGGAGGCCGAGATGGGCAGATTATCTGAGGTCGGGAGTTCAAGACCAGCCTGA CCAACATGGAGAAACCCCATCTCTATTAAAAACACACAAAAAAAATTAGCCAGGCGTGGT GACGCATGCCTGTAATCCCAACTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCG GGAGGCGGAGGCTGTGGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGA GCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAATGGAAAGCAGAGGCTAATACCA CTCTATCAAAATACTTCCAAGGGAGTTAAATTTCTATCATTCCAAAATGAAGTTACACAT TTGTTTTCCCTAGATACTTCCCTATGAAAATGAATTCCTTTATTGGTAATTTATGTGGGA AATTTTCTAATTTGGTAAAAAGGGCACAAAGAGGTAGTATAACTTTGGTCTAGTCATTTA ACCTAGGTAAATAAACAATTTTTCACGTAGACCAAGTGCCCTCCTCTATACCCTTGCTAT TCAAAGTGTGGTCCGTAAACCAGCAGAATTGGCAATCACTTGGGAGCTTGCTAGAAATGC CAAATATCAGGCGTACTATACTCCCATATAGGATACTACTAAACCCCAGACCCAATGAAT CAGAATCTGCATTTTTAACAAAATACCACGATTTATATACACAATAAAGTTTGAGATGCA CCCCCTCTATACAATAAGTACACCTCAATACATTTGACTAAATGATCTTAAGGTCCCTTA TAGTTATTTTGCATGAAAAATTATATCCAACATTAAAGCCTATATTCTTGTTCTTTTTTT TTTTGAGATGGTCACCCAGGCTGCAGTGAAGTTGGTGTGATCTCAGCTCACTGCAACCTC CGCCTCCCAGGTTCAAGTGATTCCCCTGCTTCAGCCTCCTGAGTAGCTGGGATCACAGGC ACGTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGAGTTTTACCATGTT GACCAGGCTGGTCTCAAACTCCTGACCTCGAGTTACCCACCCACCTTGGCCTCCCAAAGT GCTGGAATTACAGGCATGAGCCACTGCCTGAAGCCTATATTCTTATGTAACAAGAGTCAG CTGGAGCTGAGTTAGAGCTGCACTCTCCCTAGCTACCCCAGTCCTCACCTGGCCCTCTCC ATCTATTTATGTTAACTGCTTGGCTCCTAGTCAGCAGAATTGAAGAAGTCTGCTTTTCAG TATTTAAAAACAAATAAACAAAAAAATGTTGTCACAGGTAAAAACTCATTAGCTGAATGT TTAGGTAAAAGGAAAAAAAATGTTAATTTACCTTGATGGGAAGTAGTGAGGTCCGGGTAG GAAGTAAGGGTGATGAAAAGAGAATCTTGGTGGTGTCCCGAACAGTGTGGCTGGATGGCC AAGGGGAGGGGGCTGGTAGACATGTGGGTGTGGAATGGGAGAAGCCTGGGGGATTGGAGC ACTTCTGGGACAAGGGGAAACGCTGGAATACTCCCTAGGAGGTTGGATGGTCGAAGTTGC AAATCTGGCATGGGCAGTACTTGCACTACTTGAAATCCTGTTGGCGCTCTCTAGAGAGAC AGGAGTGGGTTGCTTCACAGTGTGAGTGGCTTCAGAATGCAGCTGATGAGTGTCTGTTTG GGAAGGCCCAGTAAAGCGTTGGGGTGGGAGTGCTGGATAGACAGGTAGACTTGGATCCTG GACAGCCACCTGAGCAGCACTGGAGACGCTGGGCTGGAAAAGTGTGACAGGGCTTGGGCT CTGGACTGCAGGTGTGGGCAGCTGGATAGCAGGTGAGGTTTCACCTTTAGAAATAAAAAT AGCATAAATCAAGAATTAACTGAGTCATTCCATGTTTTTCTTCTTTCAGTAAAGTTTAAT AAATTGTATAAGCAGAGGCCTTCATCAATCACCTTACCTAACTGCATCATCATATCAAAC CACTCTATTTCATTTGCAGCATTTTGAACAAACTGAAGTTATCTTGTTTTCTTGTTCATT TACATTTTTTGTCTCTCTCTCTCAACTAGACTCTAAGTGCCATGAGAAGAGCAACGTTTT CTGTTTCGTTTGCTGCTGTATCCCCAGGGTGAAACATTCTGTCTGGGGCAGAAGAGGCCC TCAACAAATATTTTTTAGATGAATAAACAAATGAATAAAATTATTGATAGATATATTAAA AGACTGAAAACACATAAATGCTGGTATGCATATATACATTTAAAAATAATAATAATATGA AGCTATTGACACTAGTTACCTTTAAGGAGCCATGATCTAAGAGAGGGGACAGGGCAGTGG GGCAGGAGGAAAAGCCAGACTTTCGTTTTATACCTACTGGTACTATCTGAATGTTCTGTT TACCTAAATATATTAATCTTATTTTTAATATTACTAGGGGTTTCAGAGTAGCAGTATGGG TCATTTTTCTTTTCTTTTATAAACTTCTCTATATTAAACTAAATTATAAATGACATTTAA TTTTTTTCGTTGAAAAAAACTTAAACAACAAAATTACTTCACTCTATTGTATTCAATATG AATACGAAAGGAAATTTCCAAGTGAGAACAGGACTTGCCACATGTCAACCACTGGTGACA GATACAAAAGGAATACTATTGCAGCAGAGCATGAAAGATATGGCAAAATTTTTAAAGGTA GGTGAAACAATTAATGTGTTTTAGCTTTCTGTTCTGAAGAAGACAGGACTACTGATTGAG CTGCTAAGTGACCCAAATGACACACCTGGTCTAAATTTAATTCAACTTTCCTGAAGAAAT ACAGATGGATGCCACAGCAAGAGAGTCATGATCTAACGTATTGCAATACAGTTTCGAATC CATTAATAAAGAAGATGCAGTCCAAGAAATTCTGCGGTTGGACATGTCTCTGTCATAGAC TGAAAGAAATGTGGATCTTTTCCCAGCCTCATTCAGGTGACTTCCCTCTCCTTTCTTTTC TCCAGATAAAGCAGATAATGCCCCTCTTAAAGCAGGAAGTAGGGAATTAAGGGACATAGC CACCTGTCTGAAGATGGGCTCTGACCCAGTGAAGTAGAGAAACAGGATGTAATGATGCTG CCCTGATTTTCACCTGATGAGGTTATCTGGACTAGCCCCACTATCTGTGAGGCACAGGCC CTACTCAGGCCCTTCCTGATTTATCAAGCATAGGTTAATTTCCCTTGTCCACGTTCCCTC CAAACCTTGTAAACCTATCACCTATCATGAAATAGTGTAAATCTTTGTGATTATTTGCAT GTCTGCCACCCCAACCATGATCACCAAACTGGGAGATTGAGAGCAGGAACTCTCAATTTC TATTCGTATCCCAGTATCTAGCCAGAACCTGGTTAATAAAAAATAGTTAAGAAAAGTATG AATGGATACAGCTTTATAAAAGTTCCAAAGCCTTTAAATGAATAGGAATACTCATATAAA AGGAGGATGCTGGCATAACTGGCATCAAAGACATGTAATCAAAGATCTGAAGAGAATTCC ACACTACCATGCTATAAGCGAGACAGGGTAGTGGGGTGGCGGGGATCATCTCACCTTCAC TCACGTATTTTTCCATACATGCGCACTGACCACCAGACCTTGCAGCACCACCCCCACTGA CACCATACCCATTGACCAGACCTTGCAAGCTGTCTGAAAAAACTAAGATAAGCAGCATTC CACCACAAATCTTACTCAAGGGAATTAACTCTATCGCCTGCATGTGCACAAGGGCTGCAT GTGAGAATGGCCTCCTGGCAAATTCTAGAATGACGATCTAGAATTAGAATGACGATCCTA ACCCCTAGGATTGTAATATTAAAATCTCTAGGATTGAAATACTAAAATCTCCGCCCAGGG AGATTTTCTGATCATGATCAACATATGAGTTAGCATGATTCCTTACTTGTCTGCACACCC TGCACTCCACCTCGCATATGTAATGACACTCAGCTACCTCATGCATTATGCATATCACCC TCCTGAAGACACCATAATGCACTCCCTTGGAGAGCCAGCCAGAGAACCCTTTCTCCTGTG CTGTCTCTCTTAATACCCAATCTTTCCAGGCATAAGCCCTAACAACCCCTGTCTAGGAAA AGTTTGCCTGGCCTCTTGTTAATTTCTATTACACTGAGAGCCAAGAACTTTACGCCAGTA ACATAAGCACTTTCAGAAACTAGAAACAGGGTGGGTGCCATGGCTCACATTTGTAATCCC AACACTTTGGAAGGCCAAGATGGGAGAATCACTTGAGTCCAGGAGTTTGAGACTAGACTG GGCAACCTAGCAAGATCCCATCTCTACAGAAAAAAAAAAAGAACTAGTAAGAGAAGAGGA GCTTGGGAGATAGTACTAAATGTGAGTGACAGAGTAAATAATGCACCAGACATAAAAATA ATACCAGACAAGTGCTGGGCGTGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCC GAGGCAGGTAGATCGACTGAGGTCAGAGGTTCAAAACCAGCCTGGCCAACATGGTAAAAC CCCATCTCTACTAAAAATACAAAAATTAGCCGGGCTTGGTGGCATGCACCTGTAATCCCA GCTACTCTGGAGGCTGAGGCAGGAGAATTGCTTAAACCTGGTAGGTGGAGGTTGCAGTGA GCTGAGATCATGCCACTGCACTCCAACCTGGGTGACAGAGCAAGACTCTATCTCAAAAAA TAATAATAATACCAGACAAGAAAGTAGATTCTATCAAAGAAATAGTAAAAGTAGTTATAT TTATATCTATACTTGCTACGACTACCTAACGAACTCTTTGACAGCAGAGACTACAAAAAA ACTTTATATGTTGTTCCTAGCAGAGTTTGCCCCATAATAGGATTTAAGAAACCTTAGTAG TGAAGGCGGCAGGTAAGCAGGCAAACAAATGTGCCACTGGAATTTACTCAGAAGATATCT GAGATAAAACTCACTGTTACAGGGGAGAATACCAGATTAAACTGCCAGATTTCGAATATA TTTACTGAATATCTTAATGTGATAAAAGTGTACTGGGAAGATCTAGTACAGGACAAGTGA TCGATTAGAACAAAAAGGTTTGGTAGAATACACAGTAAAATGAAATCAGCTTGAGGGCCG GGTGCAGTGGCTCATGCCTGTAATCCCTGCACTTCGGGAGGCTGAGACGGGCAGATTACT TGAGTCCAGGAGTTCAAGACCAGCCTGGCCAATGTTGCGAAACCCCGTCTCTACTAAAAA TACAAAAATTAGCCAGGCGTGGTGGCGCTTGCCTGTAGTCCCAGCTATTCAGGAGGCTGA GGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGGGAACCAAGATCACGCCACT GCACTCCAGCCTGGGAGACAGAGTAAGATTCCCTCTCAAAAAAAAAAAAAAAGAAGAAGC TTGATTGAGAGCCAAATAATGGAGAAATATTACTAGAAAATCCATGAATTCAGTGTGTGA AATATTATGCGGTAGTAATCACAACATATTTAAATTTATGATCCTGGCTAAAGAGAAAGT CAAAAAAATCTACGCTGGGGTTATTCAATTTTTGGAATATTGATATTGGCTAGGGAAAAA GGCTGATAGAGATTAAAATAAAAAGTTCATAGAAAAATGGAGATTATTTTACATGACAAT GCTAAAAACACAAAAGAAAGAAATGTGCCTCAAAGTCACAGTTACTATGGCTAACTGGCA AAAAAATAAATAAATAAAAAATAACAAAAATAACAACAACAACAACAACAAAACCTTCAA AAGCTTGTCCAAATGTACAAATGAGCCCAACTGCGGTGAGGCAAATGCAAAAAAACTAGG CAGTCCAAAGGAAAATTGAAGGAGCCACACCTGAGAGACCTCAAAGTCAATACTAATTGA CTCCAAATATTTTTACAAAAAGGAGAGAATCGGTGGAATTATTTAGTCATTACGGTATAA ACAGCAACTGACAGAGAACAGAGAGACTCAATAAATTCCTTTCTCCTAAAGAAGACCTTA AGATTTCTGAACCCTAATTTTCAAAGTAAATAGGTTAAAAATATTAGATCAACTACAGTA TAATGACAAGTTCAAAGAATGTTCTAATCCAATTGACAAAAGGAATATAAATAGATCTTA GATGGCATTCACCCAAGAATTTTTTTTTTAAAGAAGAAAACGGACAACAACAACAACAAC AACAACAACAACAACAAACCTCTGTCCAGGCATGATGGCTCACACCTGCAATCTCAGCAC TTTGGGAGGCAGAGGTGGGCAGATCACCTGAGGTCAGGAGTTTGAAAAACCAGCCTGGCT ATCATGGTGAAACCCTACTAAAACTACAAAAATTAGCCAGACATGGTGGTGCATGCCTAT AATCCCAGCTACTCGGGAGGCTCAGGCAGGAAAATCACTTGAACCCCGGAGGTGGAGGTT GCAGTGAGCTGAGGTCGCGCCACTGCACTCCAGCGTGGGCAACAGAATGAGACTTTGTCT CAAAAATATATATAAATATAAATATTAAAAAATTTTTTTAAAAAACCTCAAGGGTGGAAC TGAGAAAATTTTAGACAAAGTAGGTACAAATGGCTTCTGCCAGAGATTTTTAGAAAATTA ACATGACTTCCAGCTATTGAAACTGATGACCTTGACAACTCTAGCTTGGTGAGTCTATTA TCTACACCTGAAATGGTGGTGAAATGTATACAGTACGATATTAATGCACAAAGCTTGCTA CAGAAAAAGAGCAAATTGTTTTTATATGAGAAAAATCATATACCTCACTATCTTGATATC TTTCTTCCATGGAAATACAGCAAACATGCTTGAAAAACAAAATTACCGTAACTTCATATT TAGAATATGAAATTACTTGAAACAACAAAAAAGTATATACATTAACAACTGTATATGACA AGATATTAAAATTATGATTCCCCAAGATTATAGCACACGAGATGTGTGCTATAATCTGTT CTAACTTAAGCTTCACAAATGATTTAGAATATTAAATATACAGTGAAATTTCCAAATTTG CAAGTGATACTGACCTCTCTAAATAATATAAAGCCAAGTTGATGAGAACAATCTATAAGA ATATATTTCAAAGCCATATGATTGGGGAACAAAATAGCAGATAAATTTCATGATTTACTG TTAAGGTGTATATCTTAATAATTCCCAAATTATGCTTATAAGATAATGTTCTCTGTTTAT CTTTTGAGATGCAAGAAACAAATTTGTTTGTTTGTTTTTAGAGACAGCGTCTTGCTATGT TGCCCAGGCTAGTCTCGAACTCCTAGGCTCCCAAAGCACCAGGATTACAGGCATGAGTCA CCACAGCTGGCCCAAGAAATAAATCTTTACTGACACTACATGTCACCAGAAATAAGAGAT ATTGTAAAAAACAAAACAAAAAACTAAGCACAAACAAAAAAATCATTCTTGTCTTAGATT TGATTACTGTTGTGCATAGCTCTGAAGTGCTTCCTATAATTCTGCCTACCATACTTAAAT ACAACATCATGGAGAAAGAACCCTACCAACATTAGAAGAAATCTTCCAGTTTCTACTAAA CCCTTATCTTTGCTCAGAATGGCATAAAATTAATGTATCAAATGTCAACTGTTTCAAATA AGAACGTTGTTAATTCTGTTTCTGGGAAGAGAAAATATACAGCATTTAACAGTGGGTAGA AGCAGATGTAAGTGAGGTCTTGGAAAAAGGGATAAAAAGAAGAAAATTATATTATGAAAA CAGAAATCATAACATAACACAGGCTGGGCATGGTGGCTCACCCTGTAATCCCAGCACTTT GGGAAGCCAAGATGGGTGGATCACTTGAGGCCAGGAGTTCGAGACAAGCCTGGCTAACAT GGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGATGGGCATGGTGGTGTGCACCTG TAGTCTCAGCTACTCGGGAGGCTGAGGTGGGAGAACTGCTTGAACCCAGGCGTCAGAGGC TGCAGTGAGCCGAGATCGCGCCACTACACTCCATCTTGGGTAACGGAGCAAGACTCTGTC TTAAAAAATAAATAAATAACATAACAGAAAAACAAGGTAAGTGAACAAAGTCATAATTAA GCCTGGGTTGAAATACAAGATTAAAGAAGTCACTACCAAACAGTGAAGACTGAGAGTGCC TGCCTGTGCTAGGACAGAACAGGGCTATAGGATCAGCTTTCTGCATCTCTCTCTTGAGTC TAGACATCTGGAATGTAGCTTGTTGCTATCAATTGCTAAAATGATACATTAAAAAACAAC AACAACAACAACACTGAAAATGCCTAAGATTCTAAGAAGTCAGTTTCCAAGGTATCTAAA ACTCTCAGCTCATATGGGTGGCTTTATTACCAGAAGGATTTAAAGAGGTTAAAAAAAAAT AGAAAAAGCAGGTTTACGCAGTCTTAGTAGGTTTAAGAAAGTGGGCCAGATATGGTGGTT CACACTTATAATCCTGGCACTTTGAGAGGTCAAGGTGGGTGGATCATTTGAGCCCAGGAT TCGACACCAGCCTGGGCAACATGGCAAAACCCCATCTCTAAAAAAATACAAAAATTAGCC AGGCATGGTGGTGTGCACCTATAGTCCCAGCTACTAGGGAGCCTGAGGTGGGAGAATCAC TTGAGCCCAGGAGGGCAAGGCTGCAGTGACCTGTGATGCTGCCACTGCACTCCAGCCTGG GCAACAGAGTGAGACCCTGTCTGGAAAAAAAAAAAAAAAGTGACAGCAAGTAGTGAATGT ATAAAGCTCTCCCTTAAAGATGGTTAAAACATGTTCTGGGGGCCAGGCGTGGTGGCTCAC ACCTGTAATCCCAGCAGTTTGGGAGGCCGGGGCGGGCAGATCATCTGAGGTCGGGAGTTC CAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGG GTGTGATGGTGCATCCCTGTAATCCCAGCTAGTCGGGAGGCTGAGGCAGCAGAATTGCTT GAACCCAGGAAGCGGAGGTTGTGGTGAGCTGAGATTGCACCATTGCTCCAGCCTGGTCAA CAAGAGCGAAAACTCCATCTCAAAAAAAAAAAAACTGTTCTGGAAAAACAAACCAATGAT GGATAGCCCTATAACAAGTTATTAAGATATTAGGTTGTCAATTTTTGGTTCTTAAAATCA GTAACAGGAATGTAAAGAACTCAGAGGAGACATTTAGAGAGATTAATATAATGAACCAAA CAAATATTTGGTAGAAAATAGATTACTTCCACTGCTTTTCTAGAGCAGTGAGAGAATGGT CTCAACAAATCAGTATCATTACTAAGTTCCAGGACAGGATGCCTCATACCCCATTAGCAA GGCAGTCTTTTATGCTGTTAGTAAAAAGACTCTCCTTTTTCCTATTGAATTACCTCAGTT ATTTCCTGCATTATCTGCCTAATCTATGGGCTCATCCTGATTTGCTTAAAAGGTCTGAGG TTTTACACATGGATTATTTGCTACTCTGGCAAACCAAGTGTTTTGATCTCTACTGAAATT TTTCCTTCTCCTATTTAATGTTCTCACTTTCCCTCTTCTTTTTTTCTTAACATTGTTGTT CCAAATTCTTAAGACTAACAGAAAGAACACTTCAAACTTGAGGTAAAATTTTCTTGCAGC TATTTAAAAAATAGTAATCTACAATAAAACTAACTCACCAACTGGATGAGTGATGGGATT CTGTAGGCTGGGAATTACCACAGAGTACGTAGGTGAGCGGTAAGGATAAACTGTTGTAGG ATTTGTAGAGATGATATTCTGTGTGGTACCAGAAAATACATTGGAAACACTTAGAGGGAA TCGTTTTCGCTTCCCTGGACGAGGCTGATAAACCCAACCTATAGAAGACAAAATATGTTT AAATGTGTAGACTCCATTTAGCCTTTAAATAATTTTTTTCATACTAAAATGCAAAGCACT TTAAAGTGTTTTAAAAACAAATTATTGTCTAAAGTATCTTTTCCAGCTCCGGGATATTAT TTCAGTGAATGACTTCTCCACTGTGTATTTTAACATACATATCCAAATAGCTCCTGACTA GTGGCCAATGTTATAACTCATCATTGAAAAGAAGAGGGTCAAATTTTTTTTTTTTTTTTT TGAGACGGAGTCTTGCACTGTTGCCCGGGCTGGAGTGCAATGGCACAATCTCGGCTCACT GCAACCTCCGCCTCCCAGGTTCATGTGATTCTCCTGCCTCAGCCTCCTGAGCAGCTGGGA TTACAGGTGCATGCCACCACACCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTT CTCCGTGTTGGCCAGACTGGTCTTGAACTCCTGACCTCGTGATCCGCCCGTCTCGGCCTC CCAAAGGCTGGGATTACAGGCGAGAGCCACTGCGCCTGGCCAAGGGTCAAATGTTTTATA ACCAATGACACAGAATGAACCTGTAGTAGAGTCAACATCAAAACCGCTGTATTTGAATCC CAAAGCCTTTCCTCCACCTTATCAAATAATGCCTCACTATGACATTATTCATCTCATTTC CTCACTTTCTGTAAGTTACAATCATCTATATCTTACAATGCAATAGTCACTAATGATCAG TCACTATTTTTTTTGAGACAGAGTCTCACTCTGCCGCCCAGGCTGGAGTGCAGTGGCACG ATCTCGGCTCACTGCAAGCTCCACCTCCTGGGTTCATGCCATTCTCCTGCCTGAGCCTCC CAAGTAGCTGGGACTACAGGTGCCCAACACCATGCCCAGCTAATTTTTTTATTTTTTTTT TTAGTAGAGATGGGGTTTCACTGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGA TCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCTGGCT GATCAGTCACTAATTTTGTGCCTAGTTCAAGAAGAGTCACTCTCCTAAACTCAGCAATCT CCAAGTCCACAAATAACTTAATTTCTTCCAAAGTCAGAACAGTGGAACTATGGCATTTGC AGCCACTGTGTAATCAGAACAATCACTGGTTCACTGTAGTTGCTGCCTCTGACCTTCATT ACTAGAACCTCTCTGCCAATATTTCAGAAAATAATAAGTTTTGTCCCACCTTGCACAGAC ATGCTGGCCATGCACTGTGCATTTTCCAAGCTTAATCCCAATGTTCCCACTGCTAGGGAG AAATCGGACTCCTTTCACACTATATCATGACAGGGCTAAATCTATCAATCAGAAGGCAGG ACTATGTTCTGACAATCATATGTTAAAATGGAATATGGTGACAATCCCTGCATTCTCATT AAGCGTAGACTGCATTTTTTTTCTGTTGCTATCATTTTAACACTTCTATAGTTTACTTGC AAAATTATAGCCTAAAGCTTTCAAGATGTACTTTCATTAAACTTACATCTATCTAAATCA AAACCACAATAAAACTGCGTGTCCTCTGATTTGTATGAGTTGGTGAATATGAAATCAGAT ATCCCTTTGCTTGGTTCTATTTAAGGAAACTCATGCCCAGTGTCATTTCAATCATTGTTA TAATATTAGTCATTATTCTCTTTATTGTACATATCAGAAAAAAATTATATATTTTTGTCT TTCAATCTCAACCTACCCTAATCTTTAACTAAATAAATTCATTTAAAAGAAGTAAGAGGC ATTATTTAATTTGATTACCAGGAAATTCCTCTCTGTGCTTTTCCTTAATCTTTTGTGCTT CATCGTAATAGGGTTTCTTTTGTTCTTCACTAAGTTTGTTCCACTCTAACCCAAGCTGGA CACTGATTTCTGCATTGTTGGCTGCTGGGTTAGCTTTGGCTAGTGCTGGTCGGTGGATCC TTGCCCAAACCATAAATGCGTTCATGGGTCGCTTCACATGACCATTTCTGTCCTTACTGA AGGGAGTATCTGGTATGCCTACATGACAAAAATTAAAAGGCTAAATTAATGTGCCATACA CACACACACACACAATTTTAAGGTAAAGTGCACCTCCGTCTATACTTATTTTTGAAATAT CTGGAGGAAATATACACTTCAATATAACCAAAAAAACCTGCCAGTATTCCACAATTCCTT ACATCCCCTGAACTCATCATTCTGAACTGTAGTTTAGAATGACTCCTTTTCCTCAAAGAG GATAATATTGTTGAAGATAACTGTGGCAATAATCATGTTGAAGAGAGTAAATTGTTGGCT TATTACTTCTTTGATCTGTATTATTAGTACCTCTAACAATAATTAACATTTATTTATTTA CTACTAAAAATATTCTACCATTAAGGAACAGGAACCATGCATGACTTACTCGTGACTATA ATCTTAGCTAGGTAGAGGTTCTCTAAACATTCACAGGAACTCATCTACATGCTGCTCTTG TGTCCTTTCAAGCAAAACTATTTATAATATTGTAATACTATATTAGTTGTATTTCACTAC GAAGGTGAAGCTCTTACCAAGTGGAATCATCAACACTAGTCCTGTGTCCTGGGAGAAAAA TGAAAGAAAACAATAAAAATAATTTTTTGGGCCAGGTACGGTGGCTCACGCCTGTAATCC CAGCACTTTGGGAGGCCAAGGCAGGTGGATCACGCGAGGTCAGGAGTTTGAGACCAGCCT GGCCAACATGATGAAACCCCATCTCTACTGAAAATACAAAAATTAGCCAGGCGTGGTTGC TCATGCCTGTAGTCCCAGCTACCTAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGA GGTGGAGGTTGCAGCGAGCTGAGATCACGCCACGGTACTCCAGACTGGGCAACAGAGTGA GACTCAGTCTCAAAAAAATAATTTTTTGAAAGTCACAGAAGGCAGGTAAAATGGCTCACA CTTGCTTCTGACCTTCATTCCTAGAACCTCTCTGCCAATATTTCAGAAAAAAAATGACAG AAAATAATAAAAGTAATTTTTTTGAAAGTCAGAGAAGGCAGCCACAATGGCTCACACCTG TAACCTCAGTACTTTGGGAGGCCAAGGCGGAGGACTGCTTCATCCCAGGAGTTCGAGACC AGCATCTCTTTTTCATAAAATAAAATTTAAAAAAAGAAAGTCACAGAGCCAGTTGAAATT TCAACAAAGGAAGTTATCTAAATTCACATCTCTCATGTATTTTATCAAAAATAACTGTCC ATAAATTTATTATATTATTTTAGGATTACTTCATATATTAAAAATTTCTTAAAAACACTA AAGATGAAATAAGTAGTATAAAGAAAGCTTTCCCTTTCTTTCCTTTAGAAAACAAAAATA AAATCTAAAAACTACTAAAGATAAAAGCAACAGGGTGGAGTGGAGAGGAAGAATCAACAC AGAAAATTAAAAAAACAATAAAACATAAAGTTAATAAAAATATGAACCAAAGATTAATAT GACTTTCCAAGATGTTCATTGGCAAAGTGTTCTGTGTGAACTAAATCTTAAAATAAGAAT TTGCTAACTATATATCTGGAAATACTGAATAGAAATAAAAACATTATTTGTACTTGTTAC TGCTGCAACTAGTCATTTCTTTAAAAATAATATTTATGGCTCATTCTACTGTATTCTTTT CAATATTTCTATAAGTCATTACCTTTCAGAGGAATAAACCCTAAAATATTACATTGAATC ACGTATTGTTTTCTGCTAGAATATTTATTATTCATTTTTAAAGATAGCCTCTATAATCGG TATAAACTTTCCTGTTTAATTATAATCACTTTTTTCATTCAACACCATTATTTCTTCTAT TTCTTGATACATATAAAAGTACTGAGCTGTTATACTACAATATTTTTAATCTTGATTATT TGTAGCATATAAACTGAGGGCTATGCGCTGTCTAGCAAGAATATTTCTATTTTTGTGTAC AAAAATTAGTCCTATCTAAATACTGGGCCTTAAAATCGATTTTTTAAAAAATACTTGAGA ATCTTGAAGGCATTCGTGTATTTTACTGCTATATGTACAAGTCGATCAGAAGTGATACCT GTGCAGACTCTGCCCTGAAAACAATCAGTTCCATTACTTTACTTTTGTAGTTTAGACTTG GGAACTGCTGACAAAACAGCTATGGGCAACACAGACGCAGTTTTGAAAACCCGACTCCCC TGCTGTCTAATACCTGCATCTGAGGGCAACACGGTGAGCGGGACATCTTTGGTTTCAATT TTTACAGAAGGCTCCAGTAGGGACTGCATTTTAGTAGGCACTGGTGTCAGGGGGACCTTG GTCAATCTTATCAGCTCTGAAGGCGGAGCTCCCTGAAACTGGATCCGGGCCCCAGGGGGG ACCGTGTGGAGCGTCAAAGGGATCCTAAGGTCTTGCTGGTGCGGCCCAAAGGCACCGGAC GTTGGGGCCAAGATGACCTCCGCGCTGCCATGAACCAGGCCATTGGACGCGGGCTCCGCG CCGAGCCTGCAGTCCTCGAGGAGTCTCTCGGGTTCCTCCGTTTTGATCACACCTTCTCGG ATGGCTGCCGGGCTTTTGCCTGCCCCGCCTTGCATCGAGTCTCTCATGACCTCCTCCGCC TCCAGCTTGCCCTTCTCGTCCCCTCGGAAGTAGCCGAGGGCCGGCCCGGGGCCTTCCAAC TTGACCACCCTGGAGGCTCTAGGACCGGTTTCGACGGCCCCTCGAGGCCCCACTGACTGA TCCAGGCTGGGCCCCAGCTTCTGCTTCTTGGCCTTGACATGCAGCGCCAGGGGCTGCACC GGGTGCAACTCGGGCCTGGAGGTGGCGCCGTCTGACGCTGTCGGCGGCTGCAGGAGCCGC AGGTCGGGCCTGAACTGCAACAGCCGCGCCTGCGCGGACGAGGCAGCGGCTTCCTCGTTC TGGGCCTGAGGCTGTGGTAGCAGCAACACCTGCTCTGGCTTCACCTGCAGCAGCCGCCGC ACCGCGGGCTGTAAGCCGGACGCCACTGCCTCCCCGCACGACGAGGCCAAGGTCGCACTG GCTGCCGCGCTCAGTGTGGGAGACGACGGAGGGGGCTCCATGGCTGCTGCCCAAAAGGAG GTGCCCTCGACCGGCAGCGGGGGCGGAGCGGGACGCAACGGGCGCGGCTGAGGCGGCGGC TCGGGTCTGGCTCTCTCCATGGGGGAGGGGGACGCCCCGGCCAGGATTGTGAGCTCAGCC GTTTGTTGGCGACCTTCCCCCTCCCCCTTTCGGTTAAGAGCCTTGCAAGGCCTTTGCTAC CCAGAACCCTACGCGGTTCAAAACGCAGCTGTCTGTCTGGGCCTCACCCAATCACAACGA CCGATACCCGTGGACGGCCAATCACAGGCGGGTTTTCCGGCTCTTCCTGGTCCCTACTCT CGCCTCGTGCTGAGTCCTCGAATCACCTGCCATGGTAGGAGCCGCCGCACTTGTTGCACA TTTTCGTTCTGACTCTCTTGTGGAGTTCTCTTACAGCCGTTGTCTTTAGTCATCCCTCCC CCACCCGGAGCTGCGACAATGGCGTTGCCCAGGAAACGTTGCGCTTCCAGGCCGCTGACA TCCAGGGAATGAAGTCTTGCGTCACAAGGGGAGCGACGGCCTTGTGCACGCGCTCTGTGC GGCCTGAGTAATCTGTCGGCCCTGAGTACCACCAGGGCTTTTGAATCTTTGCCAAGGGAG AATGGGGAAGATTTTGCAACTTATCAATAACCTATTAGCTAATGTTGCTGGGGAGGATCT TCGACTTTGTGTGATTATTGTGCTAAAGTTTCAATTAATCACCAGGCCCTGTGGCCCTAC TTCCAAAATACTATACATCCCAAATTCATCCACTGTTTTGTGTCTCTACCTGCCATTATC CTGTTCCAGGCTCCCAGCATCTTTCACTGGGATACTGCCGTAACCCTGTAAATAGTCTCC CTGCTTGTCACCCTTGCCCCACTACACTCCAGCTGCCAGTGATCTTTCGAAAACGCAAAT CTAAGGTTGTCACACTTTTCCTAAACTTTCCATGGCTCCCCACTGATAATGTAATGAAAG TCTAAAATTCTTAGCAAAGCCTTAAAAATCCCCCAGTGGCTTGGGATCTAACCTCCTACT ACTGCTACTATTAGATTGGTGCAAAAGTAATTGTGGTTTTTGCCATTAAATAGTTATTGA GTCTTTGGGTTTCAGCCACATTGGCCCCATCATCATTCTCTTTCTACTGCAGGGTGTTTA AACATGCTCAGCATGCTACTCTTTCCTTTGTGTCTCCTTAATTCCTCCTGCACATTTTTC ATATTGCAGCTCAACTGGGACTTCTTCAGAGAAGCTTTTACTGACTCTGAAAATCAGATA AAATCTTGGTCTACTTATACCTCTATCACTTGGTTTGCTTACCACAATTTGTAATTAGAA TTTTCATGTGATGATTCCACTGCCTCTCCCACTTTAGACTATAAAGTCCTTGAAGGCAGA ACAGTTTGTGTTTTGCCCATCACTGAATCCACAATGCAGACCATTGAGCCTGGCATATAG TACTCAATAAATACTTGTTGAATAAATAAATGAATAGCGACTGTGATAGGGTAATAATAA AATAGTAATAATCACTACCTGTGTTAAGGGCTTACTCTTATGCTAGACACTGTTCCAAAT CCTTTCCATGTTTATGTTTCTCCTTTTAGTAGGATTGTGTTTATTTCCATTAAACATCAC CAAGAAAAACAAAAAGAAATCCTGTATTAACATTTGCTGCATTTCTAAATGACATTCTGG CCAAAAACTATAGTTTATCTTGACGTAGATGATTTTTGCAATCAAGACAAGTTATCACTC AAAGACCACTCCAATTTATTGTCCAATCCTCTGGTAACAAATGTGGTCAGTAGGAGTTCT TATACCTGGCAGATAGACAAGGGCAATGGTTTTCAAACTTTTATCTCAAGAACTCATTAT ACCCATAAAAACTATTGAAGATCCTGGGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAG CACTTTGGGAGGCTGAGGCAGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGC CAACATGGTGGAACCTCGTCTCTACTAAAAATAAAAAATTAGTTGGGCATGGTGGCACAT GCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCA GAGGTTGCAGGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACCC TGTCTCAAAAAAAAAAAAAAAAACTATTGAAGATCCCAAAAAAGCTTTTGTTCATGTGGA TTTCATCTATCAATATTTACCATGTTGTAAATAAAAACAAATTTTAAAGATAGCAACTCA TTTAAAACGTCAACAATAAAACCATTCTGTGGTAACACATTTTCATAGGAAAAAATTATA TTTTCCCCACCTTATGCTCACAAGAGAATGAAGTGAAAAGAGCAAATATTACATTAGGAT TATTATGAAAATAGTTTTAACCTAGCTGACTCTGTAAGTGTCAGTCCCCATACCACACTT TGAGAACCACTGTACTAGGGTTTAAATGGGAGAGGCAACTGTATGCATGAGCAAAAGCTG ATAAAAGAGGCAAATAAGTTGTCAGAGGTGTGTGAACCAGAGCACCTCCATCTTGAGTAG GTGCTGGGTAAAATGAGGCTGAAACATACTGGGTCGCATTCCCAGACAGTTAAGGCATTC TAAGTCACAGGATGAGATAGGAGGCTGGCACAAAGTACAGGTCATAAAAACCTTGCTGAT AAAACGGGTTGCAATAAAGAAGCTGGCTAAAACCCACAAAAACCAAGATGGTGATGAGAA TTACCTCTTGTCATCCTCACTACTACACTCACACTGGCAGCATGACAGCTTACAGATGCC ACTGCAATGTCAGGAAGTTATCCTATATGGTCTAAAAAGGGGAGGCATGAAAAATCCACC CCTTGTTTAGCTTATCATCAAGAAATAACCATAAAAATGGGCAACCAGCAGCCCTTGGGG TTGCTCAGTCTATGGAGTAGCCATTATTTTATTCCTTTACTTTCTTAATAAACTCGCTTT CACTTTACTTTATGGACTCGCTCTGAATTCTTCCTTGTGCGAGATCCAAGAACCCTCTTT TGGGGTCTGGATCTGGACCCCTTTCCTGTAACTTCTTTCTGGTGACCCAGGTGGGATTAT AGTGTGTAAGCCCCCAGTAAGTGGTGAGGTCCTGTAACATCTTTCTGGCAACTATGGAAT GGACTGCAGTATGGAAACCCCGACCCAAAGGCTAACTTTGGGTAAGTGGTGGGGTCCGGT AACATCTTTCTGGTGAACCCTAAAGGGACGATACTTAGGAGACTCCTGACTCAAAGGAAA TAGACTATAGCACTGATTGGACAATTTTGGATAAGTGGTGGGGTACCCAGATAAAGAATG GGATTGGGTTAGAAGCCCAACTTAGGAGGGTTAGAGTCCCTTCTAAGATTTAGGGGGCTA GAAGCCCCTCTCGGTAAAGTCCCCTTTGGCTAAGAACAGGTTTGGCACTACGGTATGTTA ACTTCTATTCTCCTTGGAATAATCTGCCTTGTACTCTTTGCTGATGGATGCGGATGACAG GGTTAGGCAGGTACAGGATCATGGGACATGAGGAGCTTTTTCCTCCCGTAAAGGGGAAAC TTGAGAGTCGATGGGACTGCTGGAAAACATCCCTTCACTACCGAGAAGTGGCCACCTGAA CTCTTCACTGTCGCTGCAGTGGGTGGATCTTTCTGTGGCTTCCCTGAACGCCTGGCCTTC CCCACCTTGCCTCAGGCAATGCTGTCGTCTCTCTCTGTGCAAACTGGTTGTAGGAATGGT AAAAATCACTATTTCTTACAAAGTTTTGATTAATGGAAGAAAGGATTTGTGAGGCTAGTC TTAAGCTGTAGCCAATCTGGTGTGTTTCCTGTGTCATTCTGTATTGTTCTGTCATAAAGA GGGGTACCTTAGGATAGAACATGGGCTTAGGACACCTATAAGCCTGCTGTTCAAGATGGC CCAGCAAACTGGTCAGTTAAAAACTTTGCTGCAGGTCCGTGAAAAAAACTGGATGAGGTT TCCCTCTTGTCTTGTATGTCCTTGGGAGCTTGACCTTGTAACCATGTGGCTGTGCTTTCT CTTTCACAGTGGTGGCCCGGGTTCAGGGTTCAATTCCCATCTTAGGAGATGAGTCCTTTA TCTTTTGTCTGTGTATTTATGTGTATCATGTGTGTGGTGCTTGTATATAACAGAGGTTTG ATTAATCGGTTAAAAATAATAAGTGCTTCAGTCATATTTTTGTGAGAAAAATTAAACATA TAATGCCTTTTATATAGTTCATGTGACTTAAGTAATCTTTGGGAAATGAAGACAGTTTTA AAGATTATTGGTAAAATAAAAATATCTTAAAATGTAAACATTTGGTCTAAATTATGCAGG TCAGATATTAGGTTTGCTAAATGCTTTAAGTTCATAAGCTGCTGCTTTCACTTTTGAAAA TTGTTTAATTTACCTACTTTGACCATATTAGAGTCTAGATAAGGCCTGGGGACATGTGAT GTTAGCCATACCCCAAGCAATGCTAGAAAAAGTCAGACCTTATCTGCACTTCTGTCTGTG TCCTAGGCTGCACACCTAGTACATAATTAAAATGCTTACCAACCAGGGTTTTCACCAAAA GTAAAAATCGCTGAAAGTTAACATTGTAACATGTAATTGAGACTACTGAAGAATAGTTCT ACACATAAGGTGTGTAAGGAAAGTGAAATGTGTTTTTGGTAAAAGATCATTAGAAGTCAT GAGAATGTAAATTTTCTTCCTTAGATTAAATGGTTAAATTATTGTTTTAAGTTAGATAGA ATGAAGCTGAAGGTTTAAGAAAGTTTTGGAAAGTGTGAAAAATTAATTGTAGGACATTCT GTGTGTGAATATATTAGTTAAAGTTAAAGGGGTATTCAGTTTTTCTATAAATTAAACATT GGAATAAAAGCACAAGTTTTTTTAGAGCAAAAACCTGCTATGATTTGCTCTTTAACAAAA ATATGTAAAGGGTTATAAAAGGTTTGTGAGAATCTTACCTTATAGTCAAACTGATTAAGA TTGAATACATTTGTCTATAAGGTTTTATAAAGAATTGGGTTTGTCATCAATAATGCACTA ATGCAAGAGTCACATTTGGCTTATTTGGTACAAAAACCACACAGGAAGCATTATCAAATG TAAAATGGTGTTTGGATTTTTGGGGGCTGTAATTGTATAAATGTATTATTGGTATATATT GAAAATTATTTTTAAAAGTCTTATAATTCTGATATGACTTGGTGTATATTGTGAATAATT ATAATTGTTACATAAAATCATTGTATACCACAGAAGGAAGCAAATTTCCTTATCAATTGA GACTTTAATAGTGGCTGTCCTAAGACTTTTTGTCATCCACACACAATTGTTGTCTTTTAA TCCTCTTCAAAAGTTGGTTTATAATCAACTGTAGAACTCTAACAGGTGTTCTTAAATGCA GATTTCTGATAACTTTGGAAATTGTGATATTAAAATAAAGGAAAACACTTTCAGAATACT CATGGAGAGCTGAAATGTTCAGGAATATCAAGCAGAACAGAAGTTAACTGCATTGACTGA ACTAATAGAAGACTAAAGTAATCATTTTAACTTTGCTTAAAATGCTGCTGATCCTTTGTT TTGTTTTTCAGAGTCAAGGAAACTTATCTTTTGAGCTATTTGCAGCTTGTAGCAATTGAG TAAAGTATATTGCTGTGAATAACATTTGAAGCATATTTAGTTCTCTCTACCTAATTTCTC CAGAATGTGGAAACTATTTGTGAGTATTCTTACATTATGGCAATATAGTTATTTGCATAA GTGCAATAAGAACCTCTTTTCTTTTGCAACAGGACACAATTGGAAACAGTGGTTATTTTA CCAACGCTTTGACTGGAATGGCACGTTTTCCTTTAAGGAATCAAACTTGACTTGTAAAGC CAATAAAAGCCCCTTGGGGAATTGGCCTCAGACCTTGTCTACAACAGCCCCTGTACAGGG TTTCTGACCTGTGGTAAGTAAAGAATGTCACTTTCTACAGGTCCAGGATCCCCAGGTTAT CTTGGGACCCCAAGAGGAGGGGAATTTACTCATCTCATAGGTATTTGAGGGTACAAACCT ATGGCAGGGCTCAGCTCTGAAAAAGTCTTATCTGAGATTCTTTCTATGGAATAAAGTTGC ATCAAAACCAATTTAAAAAGTGGTTATGTAAAAAATAATTATTCTCATTGCACTTTATAC AACTAATCAGGCCAATTATAGTAAAGCAAATCAGTCTTACCGTGATTTGTCTTTAGTAAA AATGGGAAACTGGAGAGAGAAATTATGTTTCAGAAACTGTGGTACACTTGTTATTAAATT CTAGTCTCATCAGTTGTTTTTAAGTTTGTTTCTGCAATTTAGGCTAACCCTGCTTATTCC TCTGAACCAACTAGTGACATCTGACTGCTGCTCAGAAGAAACAAGAGGGATGGGTAATGT AAAAATCTAAATCAGTATTCTAATTCTGAGCACACTTATGAATCTTCCAGATATCACCTT TTGTCAAAACTCGGAGTTATGAATTGCCCTCGCCATACTGATGCTTTCTGACTGAGCTCC TCTCTACCCTGAATACAAGAGACTCTCATAGTTAAGCAAGAATATCATTGCTCCTATTCA GCATGAAGAAGTTACAGAAGATGGATTTTCAACCCTCTGCAACCCTTAGGATTAAAATTA TACAAACCTTTAGGATTATAAAAGGGAGGGGGTAATGTCAGGCGTGTGAACCAGAGCAAC TCCATTTTGAGTAGAAGCTGTGTAAAACGAGGCTGAAACCTACTAGGCTGCATTCCCAGA CAGTTAAGGCATTCTAAGTCACAGGATGAGATAGGAGGCTGGCATAAAATACAGGTCATA AACAGCTTGCAGATAAAACAGGTTGCAGTAAAGAAGCTGGCTAAAACCCACCAAAACCTA GATGGTGACAAGAGTCACTTCTTATCATCCTCACTGCTACACTCCCACCAGTGCCATGAT AGTTTACAGATGCCATGGCAACATCAGGACATTACCCTATATGGTCTAAAAAGGGATGCA TGAATAATTCACCCCTTGTTTAGCATATCATCAAGTACTAACCATAAAAATGGGCAACCA GCACTCTGTCTATGGAGTAGCCATTCTTTTATTGCTTTACTTTCTTAAACGTGCTTTCAC TTTACTCTGTGGACTCATCCTGAATTCTTTCTTGTGTGAGATCCAAGAACCTTCTCTTGG GTTCTGGACCTGGACCCCTTTCCTGTAACATCTTTCTGGTGACCCAGATGAGCCTATAGT GCAGATATTCCCAGTAAGTGCTAGGATCCTGTAACGTCTTTCTGGTGACCATGGAATGGT CCCACTATACTGTGGAAACCCCCAACTCAAAGGCTAACTTTGGGTAAGTGGTGGGGTCCA ATAAGAAAGTTAGTGTTAATTTTGTGCAAGGTTTCAGTTCATATTCTGATTTCAGTTATC AAAATGTAATTGACAATAGATGCATGGGTGTATTTCTGAACTCTCTGTTCTGTTCCTTCC ATTCCTTCCATCTATGTACTATAAACCAAAAGTATCTGAGGCAAGCCTTAATCAATTTAG AAGTTTATTTTGCCAAGGTTAAGGACATCCCCGTGACACAGCCTCAAGAAGTCCTGACAA CATGTCACCAAGGTGGTCAGGCTACAGCTTGCTTTTATACATTTTAGGGAGACATAGGAC ATCATTCAATACTGTAAGATGTACATAGCTTCAGTCCAGAGAGGTGTGACAACTCAAATC AGGGCTTCCAGATCACAGGTGGATTCAAAGATTTTCTGAATGGCAATTGGTTGAAAGACT TATCTAAAGACCTAGAATCAACAGAAGGGAGTGTCTGGGTTAAGATATGGGGTTGTGGAT ACCAAGGTTCTTATTATGCAGATAAAGCCTCCAGATAGTAGGCTTCAGAGAATATCAGAC CTAAAAAGTCTATTCTGTCAGTCTGAAAGTCGCTGTTTCTATGTTAATGCTGGTCAGCTG TGCCTGAATTCCAACGGGAGGAATGTTTAATGAGGCATGTCTGACCACCCATTCCCATTG TAGCCTGAGCTAGTGTTTTAGGTTTACTTTAAAATGCCCTAGCCTGGTGCAGTTGTTCAT GCCTGCATTCCCAGCACTTTGGAAGGCTGAGGCAAAAGTATTGCTTGAGTCCAAGAATTT TAGACCGACATGGGCAACGTGGCAAAATCTCGTCTCTACAAAACAATACAAAAATTAGCC AGGTGTGATGGCCTGTGCCTGTAGTCCTAGCTACTCGGGAGGCCGAGGCTGGAGAATTGC TTGAGTTCAGGAAGCAGAGGTTGCAGTGAGCTGAGACTGCACCAGTGCACTCCAGCCTGG GCAACAGAGTGAGACTCTGTCTCAAAAATATAAAATAAAATAAAATAAAATAAAGTAAAG TAAAATAAAATAAAATATAAAATAAAATAATAAAATATAAAAAATATACCCTTGGCCAAA AGGAGGGGTCCATTTCATTGGTTGGGGAATTTAGAATTTTATTTTTGGTTTACAGTATCT CTTTTTTTTTCTTTTGTTACAAATGGGGTTCTTACTCTGTTACCCAGGCTGGATTATAGG CATGAGTCACCGTGCCAAGCTATATACATATTTTTATGCCAGTACCACAGTCTTGATTAC TCTAGCTTTATGGTAAATTTTGAAATTTTGAAATCATGTAAGTCCTTGAACTTTGTTCTT TCATTAAATCATATTGGCTTTTCTTGGTCCTTTGGATTTAAAAGATAAATTTTAGGTTCA TCATATCAATTTCTTTTAAAGCAAACCCTAATGGTATTTAGATAGAAATTATATTGAATC TATGGATCAATTTTGGGAAAACTGACACCTTGATGATACTGTATTTTCCTATTTGCAAAC ATGGGACATATCTCCATTTATTTAGGTCTTAATTTCCTTTGACAATGTTTTATAATTTTC AGTGTACTGTCCTGTACTTCTTTCATTAACTTTATTTCTAAATCCTTTATTCTTTTTATG CTATTTGTGAATGTAATTTTTTAAAATTTCCTTTGCAGTTGGTTGTATGTTGATTTTTGT ATTTTTATTTTCTTACCTTATTGCACTGGCTGGAACTTTTAGTCCAAGGTTAAATAGAAG TGGTGAGAGTGTACATCCTTTTGCCTTGCACCCAGTCTTAGGAAGAAAGCATCCAGTCAT TCACCTTTAAGCATGTTGTTAGTCATAGGTTTATGTAGCTGCCTTTTATCAAAGTAAGAA AGTTTCCTTCTATTCCTAGTTTATTGAGAATTCTACCATGAATAGTAGTTCAATTTTATC AAATGCTTTGTCTGTGTCTATTGAGATGATTATATGGCTTTTTCCTTTAAGGGTCAGCAA CATTTTCCAGAAAAGGCTATATAGTAAATATTTTTGGTTTTGTGAGCCATATGAGCTCTG TTGCAACCAATCAACTCTGCTTTGTAGCAGAAAGCAATCATAGACAATATGCAAATGAAT GGGCTTGGCTTTGTTTCAGTAAACTTTATTTGCAAAAACAAATGTCATGCCAGATTTGGC CCAAGGGCTATAGTTTGCTTTTGGCTATAGTTTGCTGACCACTGATTTATTCTATTAATA TATGTATTACATGAATTGATACTCAGATGTTAAGCTAAAGAACATTCCTGTAATAAATCG ACCACACTTGGTAATAGTGTATAATCCTTTTTGTACATTACTGGATCTAATTTGTTGTTA TTTAAACAATTTTAGCATTTACATTCATGACGAGTGTTGTTCTATAATTTTCTTGTGATA TCTTTGTCTGTGGCTTTTAGTATCAGGGTAAAATGAGCTGTAAAGTGTCCCCTTCTATTC TTGAAAAGATTTCCATTGGATTGGTATTATTAATTATTTAAATGTTAATAGAGTTCCCAA TAAAACCATGGAGGCCTGGACTTTGCTTTGAAGAAGATTCTAAAATAATTTAATTAAACG CTTTAATGTTTTTCACTGATATATATCTATGCAAATTGTATAATTTCTTTTTGAGTCTAC TTTGATCATTTCTGTTAATGAATTTGCCCATTTCATCTAAGTTGACAAATTGTTGGCATA AGGTTGTTCAAAATATTCCTTTATAAGCCTTTTAATTTCCATAGGGTTCAGAATGCTTCC TCTTTTAATCCCAATTTTGGTAATTTCTGTCTTCTCTCTTTTTTTCTTGGTCATTTGACT AAAAAGTTAACAATTTTGTAGATCTTTTCAAGGAATTAACTGTAAGTTTCACTAATTTTC TCTATTGTTTTGCTGTTTTCTTTTTATTGATTTCTGCTGTGGTCTTTAGTCCTTCATTCT ACTTTGGCTTTTCTTTTTGTAGTTTCTTAAGGTGAAAGCTTAATTAATTTTTCTAGGTTA TTGAAGTCTTCCTTTCTAATTTTTAAAGCTATAAATTTCTCTCTAAATATTGCTTTACCT GCATTAATTTTGATATGCTCTGATTTTACAGTCATTCAGTAGAAAATATTTTATAATTTC CCTGGAGGTTTTTTCTTTGATGTGTAAACCACAAATAAAATTCAAAAGCCTCCCCCACAA AAATCTGATTGGACTTTCTCCTCAGCCAGGGAACTCTAAAACTTACCCTGAAAGACTGGT TCAGGCCATGAAAGGAAGTAGGGGTTGGACATGCCTCATTACACTCCTCCAGCATTAACC AACACAAACCTTATATCTGATAAGAAACATTGATGGTCTTCTCTCTAATGCCTGCTGGAG GCTTTGTCTGCATGATAAAACCTAGGTCTTCACAACCCTTTATCATAACCCAGACATTCC TTTCTACTGATAATAACTTTTTCAAGCAATTGCCTTCAGAATATGTTTAGGAAGAAGTTG AATCCCTGAATAGACCAATAACAGGCTCTGAAATTGAGGCAATAATTAATAGCCTACCAA CCAAGTAGGACCAGATGGATTCACAGCCGAATTCTACCAGAGGTACAAGGAGGAGCTGGT ACCATTCCTTCTGAAACTATTTCAATCAATGGAAAAAGAGGAAATCCTCCCTAACTCATT TTATGAGGCCAGCATCATCCTGATACCAAAGCCTGGCAGAGACACAACAAAAAAAGAGAA TTTTAGACCAATATCCCTGATGAACATCAATGCAAAAATCCTCAATAAAATACTGGCAAA ATGAATCCAGCAGCACGTCAAAAAGCTTATCCACCACGATCAAGTGGGCTTCATCCCTGC GATGCAAGACTGGTTCAACATATGCAAATCAATAAACGTAATCCAGCATATAAACAGAGC CAAAGACAAAAACCACATGATTATCTCAATAGATGCAGAAAAGGCCTCTGACAAAATTCA ACAGCCCTTCATGCTAAAAACTCTCAATAAATTTGGTATTGATGGGATGTACCTCAAAAT AGTAAGAGCTATTTATGACAAACCCACAGCCAATATCATACTGAATGGGCAAACACTGGA AGCATTCCCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTCTCACCACTCCTATTCAA CATAGTGTTGGAAGTTCTGGCCAGGGCAATCAGGCAGAAGAAAGAAATAAAGGGTATTCA ATTAGGAAAAGAGGAAGTCAAATTGTCCCTGTTTGCAGATGACATGATTGTATATTTAGA AAACCCCATTGTCTCAGCCCAAAATCTCCTTAAGTTGATAAGCAACTTCAGCAAAGTCTC AGGATACAAAATCAATGTTGAGAAATCACGAGCATTCCTATACACCAATAACAGACAAAC AGCCAAATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTAGGG ATCCAATTTACAAGGGATGTGAAGGACCTCTTTAAGGAGAACTACAAACCACTGCTCAAC AAAATAAAAGAGGACAAAAAAAATGAAAGAACATTCCATGCTCATGGATAGGAAGAATCA ATATCATGAAAATGGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATCA AGCTACCAATGACTTTCTTCACAGAATTGGAAAAAACTAAAGTTCATATGGAACCAAAAA AGAGCCCGCATTGCCAAGACAATCCTAAGCCAAAAGAACAAAGCTGGAGGGATCACGCTA CCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGATACTGGTACCAA ACCAGAGATATAGACCAATGGAACAGAACAGAGCCCTCAGAAATAATGCCACACATCTAC AACCATCTGATCTTTGATAAACCTGACAAAAACTAGAAATGGGGAAAGGATTCCCTATTT AATAAATGGTGCTGGGAAAACTGGCTAGCCATAGATAGAAAGCTGAAACTGGATCCCTTC CTTACACCTTATACAAAAATTAATTCAAGATGGATTAAAGACTTAAATGTTACACCTAAA ACCATAAAAACCCTAGAAGAAAACCTAGGCAGTACCATTCAGGACATAGGCGTGGGCAAG GACTTCATGTCTAAACACCAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAA ATGGGATCTAATTAAACTAAAGAGCTTCTGCACATCAAAAGAAACTACCATCAGAGTGAA CAGGCAACCTACGGAATGGGAGAAAATGTTTGCAATCTACCCATCTGACAAAGGCCTAAT ATCCAGAATCTACAGAGAACTTAAACAAATTTACAAGAAAAAATCAACCCCATCAAAAAG TGGGTGAAGGATATGAACAGACCCTTCTCAAAAGAAGACAGTTATGCAGCCAACAGACAC ATGAAAAAATGCTCATCATCACTAGCCATCAGAGAAATGCAAATCAAAACTGCAATGAGA TACCGTCTCACACCAGTTAGAATGGCGATCATTAAAAAGTCAGGAAACAACAGGTGCTGG AGAGGAGGTGGAAAAATAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAGTTCAA CCATTGTGGAAGACAGTGTGACAATTCCTCAAGGATCTAGAACTAGAAATACCATTTGAC CCAACCATCCCATTACTGGGTATATACCCAAAGGATTATAAATCATGCTGCTATAAAGAC ACATGCACACGTATGTTTATTGTGGCACTATTCACAATAGCAAAGACTTGGAACCAACCC AAATGTCCATCAATGATAGACTGGATTAAGAAAATGTGGCACATATATACCATGGAATAC TATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAGCTGGAA ACCATCATTCGCAGCAAACTATGGCAAGGACAAAAAACCAAACATCGCATGTTTTCACTC ATAGGTGGGAATTGAATAATGAGAACACATGGACACAGGAAGGGGAACATCACACACCGG GGCCTGTTGTGGGATTGGCAGAGCGGGGAGGGATAGCTTTAGGAGATATACCTAATGTTA AATGACGAGTTAATGGGTGCAGCACACCAACATGGCACATGTATACATATGTAACAAACC TGCACATTGTGCACATGTACCCTAAAACTTAAAGTATAATAAAAAATAAAATAAAATAAA ATAAATATATATTTTAAATATACATTTATTTTAAATATATAAATATTTAAATAAATATAA ATAATTATAATTTATAATTTATTTATAATAAATAAATAAAAATAAAACTATATGGAGCCC TTAAGTGTTTTAGGTACTTGACATCTATTGTGTATTATTACCCCCATTTAATAGTTCAGG AAACTCAGACCCAAAGAGATGGAGGAACTTCACTAAGATTACACAGTGAGTCACTGCAAA GTTGCAAAACCTGGTCTGACTGACCATCTTGCAGGATATTCCCTTTTTTTTTTTTTTTTT TTTCTTAGATGGAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGATTTGATCTCGGCT CAAATTTCAAAGCAATGAAATTCCTGAAAGCCACTTAGTTATTGGGAGAGAAGAAGATTA AAAGAAAGAAAAATTAGTGAGTGAAGAATGGAGAGGTATTGGATGGGAAGATATTGTGGG AGAAATGGAATCTTGAAACTAAGGAGATTGGCCAAAGGTTTTTGTTTTTTGTTTTTGTTT GTTTGTTTGTTTTTGAGACAGGGTCTCACTCTATCACTCAAGCTGGAGCACAGTGGAAAA ATCATGGCTCGCTGTATTCTTGACTTCCTGGGCACAAGCGATCCTCCCACCTCCACCTCA GCCTCCAGAGTAGCTGGGACCACAGGAACATGCCACCATGCCTGGCTAATTTTTGTATTT TTGTAGAGATAGGGTCTGGCTATGTTGCCCAAGCTGGTCTCAAACTCCTGGGCTCAAGAG ATCCTCCCCTCTCAGCCTCCCAAAGTGCTGGGATTGGTGTGAGCCACTATGCCCAGATGA AAGATTCTTTAGTCCAGTAGACACACACACACACACACACACACACACACACACACACAC ACACACACACCTCAGTTCAAATGAAATCTCAGCTGGGATCCCATTCAGGTCATCAAAATC GTTAGCATATTAACATTTATTGAGCACTCATGTGCCAGGTATAAGGCCCAGCTCTTTTCA AACATGATCTCATTGAATCCTCCCAACAGCAGAATAGGTAATTTTATTAGCCCCATTTTA TGGATGAGGTTTTTTGTTTTGTTTTGAGATGAAGTCTGGCTCTGGCGCCCAGGCTGGAGT GCAGTGGCACAATCTCAGCTAACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCCCG CCTCAGCCTCCTAAATAGTTGGGATTACAGGCATGCACCACTACACCTGGCTAATTTTTG TGTTTTCAGTAGGGACGGGGTTTCATCATGTTGGCCAGGCTGGTCTCCAACTTCTGACCT CAGGTAATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATG CCTGGCCAAGGTCAACTCTTTAACATCAAAGCTGGACTCCAACCCAGGTGTCTCTTCCAC TAGGTATCTGAAGAACTTGTCACCCACTCTGGGATGGATAGGCCATTAGGGAGAGTCAGG CTGGGTTAGGGAGATGTGGATGAGGGAGAGGCTCACCCAAGAAGTGGAGGGATGGGACGT AGGAGTCCTGACTGCTGCCCCAGACTCCTATGAAATAAAGAGATGAGCTCAGCTTGTCAC TGGAAAATCTCTGTGGAGTATTCATTGTGCCTGAAGTTCTATGATGGTGGCAGTGGACAG ATGAAAAGTACTATCTCTTAAAGAGATTAAGTATGTTTGAACACAACTTCATTTCTTGTT GAAAATACATTTCATTTCCCCTCCCTTCATTCCCCCACCAAATGCATTGTACTGCTTTGG AGTACTTGGAAAAACCAGTTTAAAAACCTTGAGGCTGGGTATGGTGGTTCATGCCTGTAA TCCCAGCACTTTGGGAGGCCAAGGCGGACGGAATCACCTGCGGTCAGGAATTTGAGAACA GCCTGGCCAACATGGTGAAACCCTGTCTCTTCTAAAAATACAAAAATTAGCCGGATGTGG TGGCAGGCCCCTGTAATCCCAGCTACTTTACTCTGGAGGCTGAGGCAGGAGAACCACTTG AACCCAGGTCGCAGAGGCTGCAGTGACCTGATATCATGCCACTGCCCTCCAGCCTGGGCG ACAGAGCGAGACTCCATCTCAGAATACATACATACATACATACATACACACACACACACA CACACACACACATACAAACCTTGCTGGATGCACAGTAGACTTTGTTCCTTCCCTCTACAA CATTTCTCCATGACCTGGAACAAAAAGAAGGGAACTTCTGTTTACTGAGCACCTATGACC TGCAAGGCATTTTATATCTTACCTCATTCATTCCCCACAACAACACTTGTCAGGCATCAC GCCTATCTTACAGGCAAGAAAACCAAGGCACAGAGAGGTGGAGGAACTTAATGTCAGATG TGAACCAGGCCATACGATGCACAGGGCGTGCTCTTCCCATGCCAGGCTGCCGCCCCAGTG ATTCTCAGCTTCATTATGAGCACAGAGTTTATTTCAGCCATTATTGGCCAAAGGAACTGC TCTGTGAGGGATGCCCATGTTTGGAGCCTTCGTTTATGGTCCCTGGCCACTGACTCTTCT CCTACGGCTGTAGCTGTTGAGGACAGTGGTTGATAACATGTCAAGAAGGAAGCCTGGGAT GAAGACTTATTCCCCACACTGCAGGTCCTAGCTCCAGGCTGTCAGGCAGGGGCAGTGATT TCAGAATGTGAAGGATTCAGAATTTGGTGGGTCCAGAGGATCCTGCCAAAGGGTTAGCCA GCTGGAATCAGAGGGGTAACTTGTCAGGGAGCAGGGGGAGGTAGGTAGCTGCTGAAGTTG CTGCTAAGAGTGATCCCAAAGTTCTGACATATCTGTCTCATCCATCCATCCATTCATCCA TTCACTCACCAATCCATCCATCCATCCACTCATCCATCCATCCACTCATCCATCCAACCA CTCATCCATCCGTCCATCCATCCATCCATCCATCCACTCACCTATCTATGTGGCCCTTGA ACACACAATCAGAACATAAAGGTGGAAGAATGGGTTTTCTTCTTTGCTGTGACACCTCTG GCTTTTCCTGATCAGTGATGGGGACCTGCAGACTGGGAGTGCTTCAGCTCTGGTTCACTC TGATCTTGGGCAAGTTACCTCTCCACTCTGAGAGGTTGGGGAGGTGGAAGAAACCATATA GCTGTCTTGTGCAGATCGCCCCTCCTATTTCATCGATGGGTGACTGAGCCTGGGAGTAGG AAGGTGACTTGCCAAGGTCAGGTAAGGAATTAGTGGTAGATTTGGTACTGGATCCCAGGA TCCTGCTGCTCATTTGTAAAGTGAGAATGGGAATCCCGGCTTTCCTCACTTCCCAGGATT GTAGAGAGGACCCCATGAGATAAATGGTGGGAAAGCATTTTGACAGGTGAGGTCACAAGG CCAAAAGGTGCCAAATGTGCACCTGGGGCCCTGGCTGCTAGACTAGGGCAGATCCCACAG AGACCAAAAGGGGTCAGCAGAGGCTTGTGCTTAAATGCTCAGCTAGGATCTGCTGCAAGG CACAATGCCTGGGTGCTGGGATTGGGGAGGGAAGCAAAGTCATTTAATTTTTTGAGACAG AGTCTTACTCTGTAGTCCAGGCTAGAGTGCAGTGGCACTATCTCGGCTCACTGCAACCTC TGCCTCCTGGATTCAAGTGATTCTCCTGCCTCTGCCTCCTGAGTAGCTGGGATTGTAGGC AGGCACCACCACACTCGGCTAATTTTTGTAGAGATGGGGTTTCACCATTTTGGCCAGGCT GGTCTTAAACTCCTGACCTCTAGTGATCTGCTCTCCCCGATCTCCCAAAGAGTTGGGATT ATAGGTGTGAGCCACCGCGCCCATCAATTTTATTTATTTATTTATTTATTTATTTATTTA TTTATTTATTTATCTGAGACAAAGTATTTCTCTGTCGCCCAGGCTGGAAGTGCAGTGGCA CAATCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCGACTGATTCTCGTGCCTCAGCCT CCCTAGTGGCTGGCATTACCGGTGGGCGCTACCACGCCTGACTAATTTTTTTATTTTTAG TATAAACGGGGTTTCATTATGCTGACCAGGTTGGTCTCGAAAACTCCTGACCTCAAGTGA TCCGCCCGCCTTAGCCTCACAAAGTGCAGGGATTACAGGCATGAGCCACGGCACCCAGCC TGGCCATTTTTCTGTAGAATTCCAGGAACAGGCTGAGTGGGGATGGGGGTGGTTCTGAGG CTACTAAAGAGAAGAGCCAAAGATTGTATAGGTAAATTCTACCTGCCAACGCCCTAGACT CAAATGCATCAGGCTCACCCCAGGAAGGGCAGCTAGGGCTGCCTTGTTCTAGAGACTATA TGAAGGGCAAGGAAAAAGCCTCCTGAACCCAGGTGGAAGCCTAAATGCTAAGGGATGTTC TGGATCCTCATCATCAGATAATCCAGAGAGAAGTGAACTGATGGCCCCTCAAACCAGTGA GTAATGGGAATAAAGGAATGTGCTGTTCATCACAGCAACTAAAAGTCTGCAGGAGAGACA ATGCTCTTGAGGGTAAGGGTAGTGATAGGAGGAGGGTCAGTCATTTTCATGCTAGTTAAG AAATATTTATCAGGCACTGTATTAGGTGTTGGAGATACTGAAATGTACAAGACAGTCATG GCCCCTTTTTTCAGAGCTCAAAGTCTAGTGGGGGAAACAGACATTAAATAGGCAATTACA GGCAGACAGAGCTTAAAAAGAGGATAACAGTGGCTACCTTAAAAGGATGTTGTGAAATTT AATGAGATAATCCAGGTAAAGAGTTTTATCAGGGCTTGGCACAGAGTAAGCCCTCTAAAA ATGATAACTATTTTTCTTGCTTTGGATAGGGAAGTTAAAATGAAGGGCTCTGTGGAAGTG AAGTGTGAAGAGAGATCTATTCCAGGTCGGAGGCTAGGGAGTCCCAAGACCGCCTGAAGA AATCACAAGAAATCTGAAGAACTTTTAGCTTGAGGGAGAGGGAGGGGAGAAAAAAATAGC AACTCGTTAGCAGTTCAGTTTCACCACTTTACAGCCTATGAAGTCTTTGGCTTCCCTCAT CTGGTTCGATCTTCAAACCTAACCAGACCGGCATCTAGAGTTAATATTTCCATTTTACAC AAGAGGGAAGTGAGACCCAGTGGGAAAAATGACTTGTTCAGAGTCATAAAGCAAAGTCCG GAAGCAAGTCTTTCTGGTCCATTATGTGTGGGAAAAGTAAACAAAAACCGCGGGGCGTTA CCGAAATATTAGGTTATAAACGTGGAACAAAGTCTAAGAGTTAACGAGAGCGAGGCACCA CTTATAGGGGTGGGCCAGGTAGGTTTCCCGGGGGAGCTGGCATTGGAATAGGCTTCTTCG CCTGCTCGGTGTCAAGACCCCGCAGGAGATGGCGGATTCATTCAGGAAGCAGCCGCTCCG GGAAGCCTTAGCCAAGGGTCTTCCGGAAAGACACCAGTCTTGATCCTGGAGCCTCAATCC CCGCTGACCCAGCACTTTGGTTTCCATAGCAATTGTCTCGTCGCAGAAAGGAATCGCCTG TGCTGGGTCTTCAGACCTCAGCTCCATGCCGCTGAGCAGCCCCACCCTGGCTCAACCCGT TACCCGCCCCGCCAGCAGGCCGGGGTCACTGCAGTCCCCACGTCGAAGCGGAAAAGGTCT GCTCAGCTCACCGCACCCCACTTCTTCCAGACCCGTCCGTCTTCACAGCAACGCGCCGGG TCTCACCACGGCGGATGCCGAGGGACAATATTACCGCGTCCGTGGCCGCCGGACTCTGCA CGCATGTCCAACAGCCCCCGTCCCCTTCCCCGCAGCCAATATGTGTCTCCCAGGCAACGC GC bcftools-1.21/test/csq/ENST00000519442/ENST00000519442.fa.fai000066400000000000000000000000211467060157400215320ustar00rootroot000000000000005 45842 25 60 61 bcftools-1.21/test/csq/ENST00000519442/ENST00000519442.gff000066400000000000000000000046471467060157400211720ustar00rootroot000000000000005 ensembl_havana gene 21 45822 . - . ID=gene:ENSG00000039600;Name=SOX30;biotype=protein_coding;description=SRY (sex determining region Y)-box 30 [Source:HGNC Symbol%3BAcc:30635];gene_id=ENSG00000039600;logic_name=ensembl_havana_gene;version=6 5 ensembl_havana transcript 517 45822 . - . ID=transcript:ENST00000519442;Parent=gene:ENSG00000039600;Name=SOX30-004;biotype=protein_coding;havana_transcript=OTTHUMT00000373922;havana_version=1;tag=basic;transcript_id=ENST00000519442;version=1 5 ensembl_havana three_prime_UTR 517 681 . - . Parent=transcript:ENST00000519442 5 ensembl_havana exon 517 1063 . - . Parent=transcript:ENST00000519442;Name=ENSE00001596998;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001596998;rank=6;version=3 5 ensembl_havana CDS 682 1063 . - 1 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 5 ensembl_havana exon 12572 13064 . - . Parent=transcript:ENST00000519442;Name=ENSE00000972591;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00000972591;rank=5;version=1 5 ensembl_havana CDS 12572 13064 . - 2 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 5 ensembl_havana exon 20979 21158 . - . Parent=transcript:ENST00000519442;Name=ENSE00001234728;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001234728;rank=4;version=1 5 ensembl_havana CDS 20979 21158 . - 2 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 5 ensembl_havana exon 22999 23238 . - . Parent=transcript:ENST00000519442;Name=ENSE00000797253;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00000797253;rank=3;version=1 5 ensembl_havana CDS 22999 23238 . - 2 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 5 ensembl_havana CDS 42140 42191 . - 0 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 5 ensembl_havana exon 42140 42194 . - . Parent=transcript:ENST00000519442;Name=ENSE00002105000;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002105000;rank=2;version=1 5 ensembl_havana five_prime_UTR 42192 42194 . - . Parent=transcript:ENST00000519442 5 ensembl_havana exon 45672 45822 . - . Parent=transcript:ENST00000519442;Name=ENSE00002116582;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002116582;rank=1;version=1 5 ensembl_havana five_prime_UTR 45672 45822 . - . Parent=transcript:ENST00000519442 bcftools-1.21/test/csq/ENST00000519442/synon-splice-region-del.txt000066400000000000000000000001231467060157400240540ustar00rootroot0000000000000042130 ACA A intron|SOX30||protein_coding 42130 ACA A intron|SOX30||protein_coding bcftools-1.21/test/csq/ENST00000519442/synon-splice-region-del.vcf000066400000000000000000000007301467060157400240170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 5 42130 . ACA A . . EXP=intron|SOX30||protein_coding;type=ENST00000519442:157094796-ACA-A, ACA--TACAAACC is the same as A--CATACAAACC, just outside the splice region bcftools-1.21/test/csq/ENST00000520795/000077500000000000000000000000001467060157400166545ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000520795/ENST00000520795.fa000066400000000000000000010357351467060157400210270ustar00rootroot00000000000000>8 8:80870571-81143467 TTATCTTTTACGATGTTTTCCAAAGTCAGAGTTGGAAGAAAAACAGGTTATCATCACTTG TGAAAATCTCCTCCAAACAGCATACCACGAAATGGGACTCCTGAGTGAAGGAGAAAATGT TGAGATTCAGAAGAACTCAAGGCTATTTTAAAAATAATTTTTATTGCTAATTTTATTTGG TACACTAACAATTTTTTAAAAGGCATTTATTAAGAAAGAGAGTCACTAATTGATTTTGTT GAGTTTTTCTTTAATGTAAAAAGGGCTGTCCTGAGCCTTTGCTGATAGGCATATATCAAC ACAAAGTGATTTAGCGATTTAGTGAATGACCACTGCCCTGATATTCTGTTCTGTTAACAC AGCTAAAATACTAACAAATGTGATGTGTGCTCAACACAACAAACACTGGATTCTGCTGGT ATGAAGTGTCAGGGTGAGTTTTTCTTATGTCTTGTGAGAAATGTTTCACATTTAACCCCC AAGTATATAAAAATTAGTTTGGATTTACTCAATTCACTTAAATTAAGCAAATTATATAAC TGAGTTTAGTAAGAATTTACTGTGAGTCTTGTACCAACACTGCCTTAAAGATAGACATGG GGTTACAATCTAGTTTTGGAGACTATATGAGTTAAAGAAACAATGCAAGATTATCTATAA ATTAGTGGTATAGACAACCACAACATACACTATATATATTCAACTAGAGCTACATAACAG ATTTTAAAGTGAAATCCTTCCCTCTTTCACAGTGTGAACTTGTAAAGCACTAGACTGTAC AGGAATTACGTTATTTTAACTGCAGTAAAGATTACTGAACTAATGACATTCTATTGCTAA CCGACTTTAATAATAGCAGTAAATCAGCTCCAAAATACTGTTATTAATATTCTTATGACA CAGAAATAGTGCTGTATTAAGTAATGTTCAAAGAACAGGTCTCACAAGCTGAGAGCTAGA GATCTTTATTATAAAAAAGCTATAAAATATGAAAAAAAAATTCAAATTGTTATTCCCAGG GAGGTATTCTACCTATTTTTAATAGTTATAGGAAAATTGGCTTTTCTAACTGAAAAGACT GTAATGAAGCTTTTTCTAAGAACTACAAGATTCTATGTTATATATCTGTTGTATACACAT AGTTTTTAAAAGTTAGATTTCATTCTGAAAGATTGAACGGTACAACTTTAAATGAAAGGG AGACAAGGAGATTGCTAATACAAAATGGTTTCCCTTATCTGAAATATAATTTTACATAGA AAAACTTTGCAGCAAATAGAAATGTAAGCACATTTACAATATGGGTTTTGGGTATGAAAG AAAGGTTACCACAGAAATTTTAGTCCTAAAAAACTGAGTTATCAACCATCCAAATAGCAA ATCTATTTATTTTAGCTAATAAGACAAGTAGAAAATATTAGATTATAATCCTAGGCTTTT AAGAGCTGTATACTTCATAAAACCAGTATATATGTTTAAAAAACACTTATAACTATGCTT TATTTCAGAGGCTCATAATCTTATAAGCCAATATTAATTTTATCAAGAAAGCAACAATAA ACTATGTACTTTCTCTTCTTGAAAAAGCACAGAGGCTAAACATTGATTTAAACGTCTCAA CACTGCCAAATCTCCCACGGATTATTCCCAAACCTCAAATCCTGACAACATCCTGTTTTA CAGGGGTGACTGCTTTCCACATGGTGCAGTCTCAGAGAGACCACAGGGCTTTCCTTGGGG TTTAGGCTGGCCTTTCCTTGAACAGAGCAAAGCACTGTGGAGTGAATCACTACAGAAATC CTGCCATGACAGGTACTCTTGCTTCCTTTTTAAAGAGACAAATAGGAAAGCTAGATGGGA AAATGCCTGGCTGCTTTGTCCCTTGTCTGCACAGCCCCTCACTTTCCCACAACAGGTAGG CACAAGCATAGAATGCTGCTGCAGGCTGTAGACCTTGCCAAGAAGCTAAAACCCACTGGT TTCTACAGTTGTCCCAGGCAGACCCATTTTCTACTAATCCTGGCTCTGTGCCAGAGCCTA ATTAAGTCACTGAGAATGCTGGATGGTTAACCCTCTCTGCACCCATCTACAATTATTTGC AAAGCACTTCGATATGCTTTCACTTTTCCCAAAGATATGTGTACCAGACTGTCTCAATGT ATAGCAGTGTGAATGTGGGTGGGTGCATGCAGGTACCCCACAGGCTAGTACTTAATACCA GTGTATGTACTTACTGTAAAGAAAGAGAAGCTCAACTGTGAAGGCTAGCATTCAGGAAAC CTTCCAAAATATATGTGTGGCTTAGTTTTATTAGTTAGGATTTAAAGAAAAGTGCAGAAG AATTCTACATTTTAATTATGCTTAATCTTAGGGAAATAATTTTCCATTAAAAGAAAAAGA AAACAAGTATTTAGATCACAATGTCTGTTGTGAATCCTTTTTACCACAGGAACAAAACAT TATAGAGCTTTTGAAATTCCCAGAGCCGCTGCTGTTCATTAAAAAAAGAAAGCACCCTTT TAAGATTTAGGTGCTTTATCTTTTACAAAATGAAAAGATCAAACATAAAACCTTATTTGT AAGCAAGGCAATAGTGTCTCTGGGTTTCTTGCTAAGATCAACAGCAATGAGGATGAATGA GGGGAAGCAGTGACAATGGTCAAAATGGGTGAAAGGAAGCTCTCTGTTGAGGCCGGCCTT CCCTGATTTCAATCTTTAGACCCAAGGCCCATAACTCTGTTTAACTACTATATCCTGAAT AAAAAGTTAATTCTACTCTAATGAGAGGCAAGTGAAGCTGAACGATGAGAGGAACACTGA GTAACCTAATTGAGCCCATATAATCTGATATCAGAGATCTCTACTTGAAGATAATTCAAG AATATCTAAATTGGAATTCAGGAGAAATGCAGGAAATTGATTAGTCAGGCTAATTATTTT CCCTTTTTGACAATAGGATATCCCAGTATACACAATACATAATTAAGTAATCTTTTCTCT TTCTCTATTCTTTAACAAGAGACCTGCTACAGATGTTCAGCTTCCAACTTCCTGTTAATA TTGATGCAATTTTCTATGGACCAAAATGATAGGAATCATTTTTCAGCTACCCAAATGCCA AATTCATTTTATCCCAATAACTTTTCTCCATTCTTCTCATGCTTCAATTACTTGCACTTA CAACTCCTATTACTTTATAGGAAAATAACACCAAAATTGAAAGGTTTTCTTAAAATTATC ATGGATACACAGGAATATTTCTATTTAGTGAAGACAGAGTATTTCACACCTATGCACCAC CACAATATGGCCAAAACAAAAGAGTGGCTTAATTAATTGCTGGCCAAGAGCCACGTTCTT TCCCAATCAGGGCTTCTGCAAGATGGCATATGGTTTGCTATTTCTTACAAATATGAAAAG CCTTTTGAAGTGATTACACTTAGTATCTGTCAAAATAATTCTGTATGTGAAACACCAGCA CTGAAAAATGAAAGAAGGTATTATTTATGCAAGACGATTTCACTTTAAGTTTGAAAATAA TTTTCATTTCTAAGGATTAAAATACTGACCAGCATGCCATTTGAGTAAATATTATTTTTA TTCCACATACTGTTCCATGTAGAAGATGTCAAGTTTACTTAGGAACATTAATGTTAAATA TTATTTTTTAAGTGGAACGAATATTTCTTCATTATTGGCCCACATTTTCTAAGGTAGAAC ATATTTAATACTTAATTTTTTATCTTATTTTCTGTATTAAATTCAATCACTGTGCCATCT TTTCAAAACTGCGCTTGTAGTGAGGATGGTTAAAAAAAAAAGGAGAAGGGTAACCTGAGT TCCCAGAGGGTAGTAGTTTTATATTATTCGTCGTTGTATTTCCAGTACCGAGGATACAAG AGGTGATCCTGAATGGCCATGCTTTGAATAACCACCAGAAGCTACAGGAGCCCAGTGCAA CCACCCAAGCTTACTCTGAGAAGCACAAGGCAAGGGGGTATGAGCTAAGTAAGCCCTGCT TACAGGACTCTGGTTCAAAGGGCAGAATAATCCAGGCCAGTGGGCATCCTGAGTGCTTTC TCATCAAGGTCCCAGTGGGATTTGTAACCATCCACTTAGAAAGATAACGCCTCCAAACAT TCAAGAGACAGAAAGTATCAAAAAATTAGAAAAATCTTTAGGTTACAAGGTCTTAAAACT TTTCGTCTATGTCCTACAACAGTTTCACTCCTGATATACTTCATAATACCACTAGTGACA GCAGGAATTAGAAAAAGTAATCCAATAGATTTTTATTTTAAAATTGTACCCTAATACCTA GCACAGAATCTACTAAGTTTTCAATAAATATTGTGAAATAATGAATTGCGGCAGTGAATG AAAATATGAAAGTAGGGTGCTCAAATGGTAAAGGGATTTTCACGGTTAGTTGGAACGCAA TTCTAAACATGTTTTCTTTTACTAGTATAAAAGTGATTCTTCTCCACAGGACATTTAGAA TGTGATGTACTGGGACTAATTTATTCAAATGTTTGCTCCTTAGATCACTGAAAGAAACTA GGAAGGATAGGCCTTATTAACATAATTGATAGCCATAAGCCTCAATTCACTCTGATGTAC TTGCCATGCCTGGGGAACACAGACCTCTTGGAAACACTGTCCTGCATTGGAAGAGCATGG CAATGAAACACAATGGATAAAACCCGCAGGCAAGCAAGGAAAATTACGTTATGAGGGGTA GCCCTTTCAAAATGACTTAGTATGATGATGTGATTGTACAGGATAGAAATACAAAATTAT CTTTACCTTACACTACTTAAAATCTAAAACTGAATCAAGATTATTCATGCTGGAGTCAAG GAAAAGCACCGTATTCTCAAAGAAAAACATATGCAAACATCTGTGGCAGAGGCTATTTTA AAGTATCCATCTTGTTGATCTTTTAGTCTTCTTAGCCTACTATGTATTTTCAGTTAAAAA TCATTAAAGTCCACCATATATGAACCCAGACACAGGACAAAAACAACAACAACAAAAAAC CACGTATTTTTTTCCATGGGGGCGGTAACCAGATGTCAATAGCTGCAGCTGTGACTATAT AATTACCTGTTTGCATTAACATAGACCACAGTTTAGATTTAATAGGTTAGATGACAATGC AGCAAAATGCATTTAGCCTATGATTACCCCCTTTCCAAACATTCTCTCATTCGCAACTTC GACCCTGGGAACATAGCAGGCACAGACTTAGGTCAATAAGAAACACTGGCCAGTACAATA GGCCTTGCCTCAAACAGCACTGTTGACAGACACCAGCACAAAGGAAATGAATAGAGTCCC CCTCAGTTCTCACACAGAGCGAAGAATGACTCAGTGTACTGCTGCTTTGGTGCTCTGTTT GTACAGTGTATACAGCTTTTGTCCTCAGCCACTGTTCACAGCTCAGTGGGGGCTAAAGAG CCTAGGAAGTGAAGGCGGAAGAATGCTCCACACTCGTCCCTGTGGCCAGCAGTTGTATCC ATATGCACATGACAGGTCAAGTGAGAACTGAAAGTCACTAGATGAAACTCTCCTACCAAG CTTACAGGAGTGAAGTAATTTCTGAGTTAAAATATAAAAAAGGTAAAATAGAAAAGTCAC CATTAGTTTGATATTTATAGAGTTATTGACTGAATTATTGTTCTTTTGTTTTTCTCTTTT CTGTCATATTTCTCTTATGGCCACTTATACAACCTTTTTCAGAGGTTGGGCACAAAGAGA AATCAGGATTGGCTTAAAGTAGGGAACTTAAGTAATGTAGGCCATTACTCAACAGAGATT GCTGAAGTAGGGCCAGAAAGCAGGTGAGGCAATATCCAGGTCTGGAGTCTGAAGCATCAG CAAGGGTGGGCAGTGGCTTTGCTTGTTGTGTGTATATTAATATCATATTGTCCCAAGCAC ATACACATCTCTCTTTAGGCCCACTTCCCAAAGTAGTGGGGTATAACAATAAAGAGCCCA AGCCAGGGATAAAATAAAATTCTAACACAATTCAGCGGAGACTATAAACAGACAGATACT TCCACTGGCTTAAAATGGTTTGCTTGATACTGGCCAAAAAACCTAGTTAGAGCAAAGTAC AAGCTCAATTGCTAAATGAAATGTCATTTCCCTAAGCCAGAAACATCTTGGCAGAATCAC ATCTGTATTTAAGCATATGTGTTTTGGAATTAGACTATGTTCAAATTCTGGTTCCACCAA TTACTAGCTGTATGATCTTACATAACCCCTCCAGTGTCTTGATTTTTCTCATCTGCAAAA ATGAAATGCTCGCCCATTTCTTTATTTAAAAAAAAAATAACTGAGATAATAATACTAGCA CTTACTTCATTGGAGGCTGTGAAGGTAAAATAAGTGAATACATGGGAGGTGCCTAGAAGA CCTGGCACCATGTGAGCATTCAATAAATGTTACCTATGAGTGTTAGCCCCAACACTCACA CTATGACCACTGCCATGATTCTACTACTATTAATAACATCAGAACCATCACCAGCCCTAC AGCGAAGGAAGTGCCATATTCATGACTACAAGAACATTCTTGCCAGATGATCAAGATCAC TGTTCTTGAGTCTATGAAGATATCCTATTTACCCAGAGGCTGTTTTTAGTGGTCTCTAGT AAGTAGATGAATTCAAGCTTTATGGATGCTGTATATGTGACATAGCCATATATAATACAC ACACATGTATTAATATTAACATTTTTAAAAGGTAAGTAATTTGAAATTTCCCTCAAGTTT AAATCAATCTACAGCCTAATAATTATTCTTAGGGAGAAAAGACAATAACAAACATTAATT AACTGCTCACTATTTTAGGGGCCAGATATTCTTCTAAGTGATTTCTCTAAAGTACTATTA TTTTTACAGGAAGGAAATTGAATGATAGTGTTAAGTAACTCACTTAAGATGACACTGTTA AATAAGCAAACCCAGGCAATTTGACTTCAGATCTTGTCATAAATATAACACTATACTGTC TCATTAATATTCCTGTGAAAGCATCTACCACAACTTGCTAAGTAGTACTATCCTTATTCT TATGCTTAGCAAAGGAAAGAAGTCACTGTCTTAGAAGATCTGGCATAGAATCAACCCATA TATCCACAGTAGTCTCATAAATGATAATATATTAGGAATTATGATATGCTTAAGGTACGT CCTTTTATCCTTTTTGAATAGGCTGGGGCTGACTATATCTGGTTTAGTAGGAGTCAAAAA GTAAAATGCTTTAACTGCTTTCATAAATCCTCATCACTACACAGCTATAATTAGTTTCAC GCTTATGAATTTTATCTTACATGTTAATTATATCTGCAATGATTCTGAGAATGCAAAGAA ATTAATTAATGAAAAAATAACTGCTTTGAGAGTAGATGCTTTAAGCATATAAGTGATAAC AGGAAGAAAAAAATGTCCATTGTTTTGATAACTTTCAGAATGTCTCTCTATGCTTAAGTC TTCCACAGTATCGGTCAATTAAATATCAATACCAAGCAAGAACAATGTCAGCTGATTAAG TAAAATTTTGTACTTCTTTAAAAGTTCATTTCATAAGGCTCTGATTTTATTCTTAAAAGT CTGAGCTTCTGAACATATGTAAGTATTCATGAATGATCCTGATTTTAAAAAAGAAAGGTA ACAGACTTCCATATCTAGCAGTATGTTAGAATGACTAAATTGACCAAAGGTTCTCCTAAA AAGAAAGAAACATAATGGTTAAAATAACAAAAATATTTTCTTTAATTCTATTATTGAGTC AGCAGTTTAGGAATGATTATAGAAAGGCAGAAAAAAGAAAAGAGCTACAAATCAAAAAAT AAACAGAACACTGAAGCTGGGTTTTGCAGAACTTGAGTGAGCTTGTTTTAACATTATAGA TATATAAAGGGTCAATATATAATAAAAAGCAGAATAAAGTTGCCTAGAATATGAAAATTC TAAACTTGCATGAAAGTAGTAAAACAGCCTCAAAATATATAAAAGCAAAAATTAAAATAA TTACTAGCAGCAAAGACAAATCCACCATCGTAATGATTTTATAAATGGTACATTTACACA AGTTGACCAAACACTGGTCAAAAAAGTAAGTTTTAACAAATTTGAAAAACTGGAGTCACT TTCTCTGCTCTCAATACAATTATGCTAGAAATCAATAATAATTCTCATTTCTTTGAAAAT TTAAAAGGTATTTCTATGTAACTCATCAGTCAAAAAATAATGGAATCTAGAAAACGGTAT GAAAAAGTACGTGAAAAATTGGCACAGTTTTTCACATGAACGATATAACAGCATGATATA ATCTTAAAAAGCACTTTAATTCTTGTGAATTAATTTATTTAATTGCCTGTAGTTCGTCTG GCTTTAGTGCTTTTGTCATTCATAGAATACTCAATTAGCACAGTTCATAATCATGTATGC TATGTATAAAAAAGTGACCAGTATTTTTTCATGATAATAAACCTGTTCTATCTCACTTTA TACTTATGAATAATCTTCTCTGGCCGGGCTATTCCAAGGTATAAATTGTTTGAGTCAGTT TGACATCTTAAAATTTTCCATCCTAAAAGTATTTATGATTCTTTGACCCCAATTCACATA TCATTTTTTTAAACTGTTGAGTAACTGCATACACACATTTAAAAGCAATCTTGATTTGAG TAGTTCCTATCTAAGGTCAAACACTTCAAAAATTGTAGGCCTAGTATGGCTAACAACATA TCCTAGTAGCATATCTTTTGACAACAGGCAAGAAAGAGAATGAGAGCAGGAAGTATTAGT GTATGGATATTGAGTCTTGGCTCCTAGAAACTGAGAAGTTAAAAGAAACACAGACAATGA CATTCATTCACTCACTCACTCACTCTCCTCAGCTCTTTTCTCTCCACATGTCTGCATGCT TCTTCTTTCTTTGGATCAGCTTTCTCTGTTCTCTAGTCTGCATGGCATATAATATGGCTA CTCAAAGCCCTGAAATTTACAAGTTAAAGCCCCAGACATGTTAAGAGACTAATTCTCTTT CTCCTGTTCCCAATTCCCAATTCCAGGGGACTTGGATTGGTTCCAGCTTTGTTCAGATGT CTGTTCTCGTCTAATCAGCTGTGGCTAGGTGGAAAAGGCCACATAGTTTCCCACTGACCA CTGCTTGGGTAGCAAGGGGTAGTAAAAGGTTTTGTTGTGAGCAAGAAATGGCATAGGTGT ATCAGCAAGCAACATGTGCTACGTGTGTGCAACGTGCTTTCTGATGGAATCCTAACACCA CCCTATGCCTGTTAGACAGGTGTCAAGTTGAATAATCAAGATGGACGGCATTGCCTGGGG CTTTGTGTAGGGAAAGTGATACTATTTGGCACTGGACAAAGGTGTGGAGGGTAGATTTCC TCAAGTAGCAAAAGACTGTACAGCAAAGAGACGTGTGGCCAGCACTGCCCCAAGAAGCTG ACGGGTCACATCTGAACAGAAGCTGCCAAGTATACAACTGATACATGCTATTAGTATATG TATATATACTATTAATATATGTGTATATATCATATAACTGATACATACTATTTACATTAT CTTGAATGTACAGATTTAAATAATCAAAAGTGAGTATGGCAAAATAATGCATGATTAATC CACCCATTTGCTCAACCTATAAATTCTAGCATAACCCTTTCTCTTCCCTATCTCCTTCCT GCTTATTTACTTATCAATTCTTACTCCAAAATACCTTTTCAATTGGTTCCTTCCATTTCA TCAACAATACCACGGTCTTAATTTGTCTTATTATATCTCTTTTCTAAATTTTTGCAATAG CCTCCTAAATGACTGCCCTGCCTCCAAATCTCCAATATATTTTGTACTAGCTTCAATTTC CATAATTTCTACTTTAAAGCAAGATCCTGTCCTTGTCACATCCCTGCTTATAAGTCTCTA GTAAGTTCGTCACAGGCTACAGCAGAGGTCCCAAACATAAGTGCACATCAGAACCACATA AATTTCTGGCCCTCATCCTAGATTTTCTCAATCAGAATCTCCTAGAATGGGGCTTAGAAA TTTGTCTTTTTAACAAACTTCCCATTTGATTCTAGTAACCTGTCCAGCATCAATCTTTGT ATCTGTGTTACAGAGCCACTGTTCTATAATATAAAGTCCAGACTCCCTGAATAGAACACA AGTCAATTCACAATCTGATTCCAACCATTTTCTAGTCTCAGCCCCTGCAACTTTCCCTTC TCAACCTTTCTCACAACACATTATGCCCTTTAAGACTGTCAGGTATCTATATATCTGCCT TCTTCTCCTCTCTCGCCTTAGGGAACTTCTACTCATTCTGGGACAGAGTGAGACTCTGTC TAAAAAAAAAAAAAAAGAATCAGTTCAATTGTCACCTACTCTGTGAAGCTTTCCTTGACT GCCTCTAGCATTTATTCATTCCCTCTTGATTACAGAGTTGAAGAGACAGTATAGTGTGGC CATTAAGAACACAGGTTCTGCAACTAGATTGCAAATGTTTGAATCTAGGCTCTGATAATT TCTAATAAGTCAGTGAGTAACATGTGTACTTGGACAAGTTAATTGGTCTCTGTGCCTTAG CTGCCTTCACTGAAAATGGGAATAATAACAGTGTGTGTCCAATATAAATTCTAAGGGTTA ATGAGTTAATGTACAAAAAACAGTTGCTCAGACCCTAGCAAATGATCCTTAAATATTAGC TTCGTGTTTAAGAGTTATTCCTGTCCCTTAGACTATGAACAAGTCTATTATATTAAGCCA GTCAATTTAAGAGTTCCCCTTGTTAGTTGTGGTACCATAAATGAAGAAAAAAATAATAAT TTAACAGAACTTATTTTCATCTCCTCAAAAGATGACTGAGGATAATGTACTAAACCTATT TAAGAAAAAAAGCCATTTATGTGAGAAGGGCTTAGGTTATCTTTTTAAGTCATTCACTTG ATAGGAAGAAACAATTTGGAAATCTTAGACAACTATTTGAATTTCAATGAAGAAAGAAAA TATTAAACATAGCTCTGGGCTATTAAAACTGTATAAAGAACTGAAAAATCTAGAAAGAAA TCTCACAGAACAAAATTCCTGTTATTATAAAACCAAAATTTTAGCCAAAAATATATCTCA AGAAATCCTGTAGACTTTTAAAATGACTAGAAATAGAATAAAAACTTTTTATAAATCCTG CCTTTTATTACTAAAGTCATATCTGAAATGGAAAAGATGGGGTAACGGAAAAACCTGGTC ATCTGTAACAAAAGAAAACAGAGGCTGACGCAGGAGGATTGCTTGAGCCCAGGAGTCTGA GACCAGCCTGGGCAAAATAGCAAAACCCCACTATAAATTTAAATTTATAAAATAAAAAAA TAAATTAAAAATAATAAAGGAAAGCAAATTACGGTTATGTAAGGTAAGAAGTAAACAGGA AAACTAAATTGGTGCTCAGATATAAAGTGAGCATCTTCTGTAATTTTCCGTTTTTCTTAT TTTGCTTTGGAAATATTAGCTATTGAAACAAAATATAGTGAAATCTGGTAACAGGAGTCA GCTCTTCTGCAGAACACATTTCTCCTTGGACGCATTCATTCACTCAAGTGTTTATTGAGC AACTAATATTATACATGCTTGGATATAGCAATAAACAAAAGAGTCATTCAAGTGTGATGC CATTCCTACAGTACTTATCATGTGAACAACATCGATATTCCAACAAGTTCCATGATACTT TGTATACCTTTTATACTGACATAAGGTGCATATGGCTCCACCTGCAAATTATCACCATTA GTGACTCCAGAAGAGTAAATCTATTTTGCTTCCATAGCATCTGACCTCCAGATCACGGGT TTTTTTTACCTAGATTCAAGGATACCTAAAGGTTAATGGGTATATTGGGGGAAATCTGTG AACTCCTTAATACTGCATGCCTATACTGTATTCTCCAGGGCCCCAAGACCCCAAGAAGAA TTTTTTTAAAAATCAGTGCTCTACATGTAGAAAATTCTCTAGCTATTTGAGCAATTCTGT CCTACTGAAAGGGCTGCTGCCATATACCAACACAGAGGATAGTTGGTAAACTCCTTACCT GACATTTTATAGGACAATGTTCAACAATTTTATCATCAAGAAGTTATGTTTTGCTCATCT AAATTCTGTCCTCTCCTGTTTTGAATACCAACAATCTAGTCAGTCTGTTAGACAAAGACT TCTTCCAAAAAAACTGTTTACAGAACTTGGGCTCCAGCAACTTTTGCAATATAATCCTTG TGCACTACTGAACCACAGAAAAATAACTCCTTAATTTGTGGTTGGAATAACCACTGCAGA ACAACCTACAGTGGGTGGCATGAAACTATCACAATTATAAAGTAACCAAGCAAATAATAT ACTAGGTCTCAAAGAGATAAAATGTTATAAATCCAAAACATACATTGCTATAAATAAAGT CTGTGGTTATTTGCTGAGATGCTCTAACATTGCAGTAACAAGGGTTACTCTTAGCATGTT TTATAAAGAAATAACTAAAGCTATTTGACAGTAGACTCAGTGGCACCACATGTATTGTTT GGGCTAAGAAATTAGGTGAATTGCACTGTATAGTAACTTTGGAAAAATGCCGCCTTTAAT ATAAACAAACAATGGACTTTCCTTTAGAAGCCACGAGAAGGGAGAGGAGGACAGCAGGAT TTGTACTACCAAATCAGCATGCCAGCAATTTGGGAAACCATTGAATAAGAGCAATCAGTG TGTCTAAATGCATATTTGTTGACAGCTGTAATCAGATCATTTCCTCAAAATTTAAATAAT GGATTTTAGAGTTGGGAAGGCTCTTTAAGACCAACCAGACAATGGGGACTGAGGACTAAA AAGGGTGCATGACTTGCTCAAGTTCACCAAACAGAACAGAAAGAAAGAACTGAGTCTCTT GACTCCCTTATCAAGCTATCTTTCTTACACAGAAAGGTTTTTTTAATTAAAATATAATTC ATGTGCTACAATTCACTAACTTAAATAAACAATTCAATGGCTTTTGGTATAGTCACTAAA AACAGCTGTGCATTCATCATCACAATTTTTTAACATTTGTATCACCCCCAAAAGAAACTC CCTTAGCTATCACTCCCTTAAATGTCCCCTACCCCACCCACTGCCTCCCATCTTCCCATC CCTAGGTCACCACTAATCCATCTTCTGTCTCTACATACTTGACTATTCTGCACATTTCAT ATCAAGGAATCATACAATATGTAGTCCTTTGTGACCAGCTTCTTTCACTGAGCATAATGT TTTCAAGATTCAGACATGTTGTATCACGTCTTAGTACTTCATTACCTTTTTTTCTTTTTT GAAATGAAGTTTTATTCTGCAACCCAGGCTGGAGTGCAGTGGTGCGATCTCAGCTCACTG AAACCTCTGTCTCATGGGTTCAAGCAATCCTCCTGCCTCAGCCTCCTAAGTAGCTGGAAC TACAGGTGGGAGACACGCCACCACGTCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGG TTTCACCATGTAAGCCAGGCTGGTCTTGAACTCCTGCCTCAGGATCTGCCCGCCTCAGCC TCCCAAAGTGCTGGGATTACCGGTGTGAGCCACTGTGCCCAGCCCCATTACTTTTTAATG GCTGAATAATATTCCACTGTATGGCAAGTTCCACATCTGCAATTTCCATACAGGCAAGTT CCACATCTGCAATTTCTACATCTGCAGATTCAGTCAACCACAAATAGAAAATATTCAGGA ATAAAAGCCAATAAAAATATAACAAAATATAAATAAAATTATCTGCATAGAATTTATCTT ATATTAGGTATTATCAATAATCTAGAGATGATTTCAAGTATACAGGAGAATGTGTGTAAG TATACCCAAGCACTATGCCATTTTATTAAAGGGACTTCAGCAACCATGGATTTTGGTGTC TGTGGGGTCCTGGAACTAATCCTCCCACAGGTACTGAGGATACCTATACCCCATTTTGTT TATCCATTCAGCAGTCGATGGACACTTGTATTGTTTCCACATTTTGGCTATCGTGACTAA TGCTGCTATGAACATCTGTGTACAAGTTTTTGAGTCGACATCTGATTTCATTTCTCTTAG GTATATATGTAGGAATGGAATTGCTGCATCATATAGTAACTCTGTTTAACCACTTGGGGA ACTGCCAAACTGTCTTTGAAAATGACTGCACCATTTTACATTCACACTCATCGAAAAGTT CCTGCTTTTAAAATCAAAACAATCAGATCACAAATTCCTTAGTTTCTGTTAACAGGTAAC TGAAGAAAAAAACCCAAATATTGACACACGTTTTTTAAAAACCACATACTATCACTACAC AAAACTCAGATTCAGAGTTCGAAACAGAGAAAGATAGCTTTAAATTGCTATTTTACAAAG GATTACAGTATAGTGAATATTTCCTTAATTGCTGAAATCATATCAAAATATCACACAAGG GCTATAGATAAATGTCAAACATTCAAAATATTGGGAGATCTTAAATATAAATTAAAAAGG AAAAATTGATTGAATGCTCTCAAAAACCAAATTAAAATCTATTGCCAGGTGATTTTTACA TACTTTCAGTCATTGGAAGGAAAACAAACATTTTTAAGATACAAAATTGATAGGTATTCA ACAGGGCAAAGTAAATGCAGTATACTGGTTTGGAACACAAAATGAAAGCTAGCCACTATA ACCATACAACAAAGAGTTATCGTCCAAATGGGCTTATGATAAGCAATTTGGGGAACAACA ACTTTATACACAATGCAGTCAACTGTACATTCTGGATGTCAAGGGGTTCTGCTTCCATTT ACTGGATAAGCTTCATATATATACATTTAGAGTTGGACTCTCAACACAGTGAAAGAGAGA GAGAGAGAGTGTGTGTGTGTACATATATTTAGAGTTGGGATCTCACTGTGTTGCACAGGC TGGAGTGCAGTAGCTATTTACAGGTTTGATCATACCACACCATACCCTCAGCCACGAGCA GTGGTGTGTGCCTGAAGTCCTAGCTACTCAGGAGGCTGAGGTGGGAGAATCCCTTGAGCA CAGCCTGGGCAACATATGAAGACACACCCCCATCTCCAAATAAATAAATAATGAAATTAA AAAGCCAGCACATTATAGCCTCAAATTCCTGGCCTCAACAGATCTTCCCACCTCAGTCTC CGGAGTAGCTACAACTACAGGCCTGCAACACCACGCCCAGCTAGGGTGTGCCTTCTACAA AGGAAGGTTGGGGCAACTAGTAAGTGTAAAGTCGAGATTAAAAGAAAATTTGGCCAAGTA TCAGCAACTCCCATGGGTGTTTCTGCCACTCAGAGACTCTAGAACTTTGGAACAGCAGCA GGTAGACAAGTGGGTAAGAGGAAAGTGTGAATAGAAACAGAAAGAAAACGAGTTCTCACA GAAAAGGGCCAGGAATAAATTAATAAAAAAAAAAAAAAGAAAGAAAGAAAGTGAAGAATC TAAGCAGATACAAGTAGGTCGTGCATAGAAATCTAAACCTCTTATTTTATTATTTTTTAG AGATAAGGGTCTTGCTATGTTGCCCAGGCTGATCTCAAACTCCTGACCTCAAATGATCCT CGGCCTCACAAAGTGTTGGGATTACAGGCATGAGCCACTGCACCTGGCCTAGAAATCTGA ATTTTTATCACATTTTCAGCACCAGCAAATTTGCCCTTTCTTTTCAGTGGTAGTTAAAAT CTTCCAGAATTGTCTTTAGCTTTACTAATCTCCAGACAATGGTGGCTGATGAACTTTTTG ACAGTACACCGAAGAAAGAACAGTTTATATCATAACTAGCACCCTCATAGAAATCTTTCT AAACATATACATATAAACAAACGAGGCCGGCGCGGTGGCTCACGCCTGTTATCCCAGAAC TTTGGGAGGCCGAGGTGGATGGATCACGAGGTCAGGAGATCAAGACCATCCTGGCTAACA CGGTGACCCCTTGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGTGGGCGCC TGTAGTCCCAGCTACTCGGGAGGCTGAGGCAAGGAGAATGGCGTGAACCCGAGAGGCAGA GCTTGCAGTGAGCCGAGATTTCGCCACTATATTCCAGCCTGGGCGACAGAGCGAGACTCT GTCTCAAAAACAAAACAAAACAAAACAAAATAAAAAAACAAAAAAAAAACAAATGAAATG TTCCCCAAAAGCACTAGTCTTGCTATTTTGGTACAGCCTAGTATTTTCTATTCTATTTCA TATTTTTAAAAAAAGCTGAAAATGGCCCAATAAATTATGATGTGCAGTTTTTCAAGGATA AAGCTCATAGGAAATGATGATAATATAATCAACCATGACTAACTTCAGATACGGGCAGGC AATGACAAACTACATCCTAAGTGTCACCTGGCCAATAGTAATTTCAAAGAGGTAGGGCAG GCTAAAATACAAAAAAAAGTTTGTCTCATAGTCAACAAAATTAGGTAATAAAAGCTCAAT AAATGAATATTAGTTCACAAATATTACATTTTTTATTATTATTACGGAGGGCAGTAGGAA TCCTGACTTAATTCTAAAATAAATTTCAAGTAATTTCAAATAAATAAGGCTAGGCACAGT AGCTCACACGTATAATCCCAGCACTTTGGGAGGTCAAGACAAGAGGACTGGCTGAGCCCA GGATTTCAACATCAGCCTGGGAAACATAGTGAGACAACCCCCACCCCATCTCTACAGAAA AATGTACAAAAATTAGCCAGGTGTGGTGGCATGCACCTGTAGTCCCAGCTACTTGAAGGG CTGAGGTGGGAGAATCACTTGAGCTTGGGAGGTTGAGGCTGCAGTGAGCTGTGGTCATGC TACTGCACTCCAGCCTGGGCAACAGAGCAAGACCCTGCCTTGGAAAAGATAATTAATTAA TTAACACTGAAATATACAACTATAAAATACTAGAGAGAAACACAGACCACTACTTTTACA AAGGCAAAAGCCTTTGTAAGTATGTAAGTATGGTACCCAAACCAGAAATTATAAAAGAAA AAGGCAAATGAATTACATAATACAAAAATTTTGTATGGCAAAGTAATCAACAACAAACTG GAGTAAATTTTTTTTAACAGTTACAACAAAGAGTATAAACTAACAAGAAAGTGATAAATA CAAAAGACTAATGAGCAACCAGAACAGGCCAATGACTCTGGAGTACAAAATTCATTTAAG AATTAAATAAACGGCCAAACGTTCAACATTGCTAGTCATCAAAAGTGCAAATTAAATCAA TAATGTAATAACTTTTGCTTATTAGATTGGCAAGATGAAAAAAAAACACCTAGTGTTGGA GAGAGACAGTTACTTTGGAAATTTGAGAATGTGTATAAATCTTTAAAGAATGTACAACCA ACCTATCCAGTTCCTCCACTCTAAATAATTTATTATAAGGAAATAATCAGATAGTTATAC CAAAATCTATATACAGATAAAAATAATAAAAACTGAAAACAACATCAATATATATTAACA GGGAATTAGTTAAAGAAGTTGTAGTAGTAAAATGCTATGCAGTCTTTAACAATTTTGTTT ATGACATAGTTAGCTGGCCCTGACATATGTTTATTTGGGAAGGCGGGGGAAGACCTACTT ATGAGGCAGTATGCAAAAATACTGGCAGATTTCTGTTGTTGTTAAGAATCTTTTTTTTTT TTTTCCAGACCAAGTTTTGCTATTGTTGTCCAGGCTGGAGTGCAATGGCGCAATCTCAGC TCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGTCTCAGCCTCCCAAGTAGC TGGGATTACAGGCATGTGCCACCAAGCCCAGCTAATTTTGTATTTTTAGTAGAGACAGGG TTTCTCCATGTTGATCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCCTGCCTCG GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCTTGTTAAGAACCT TTTTTAAAACATATATATAAAAATGCTGGCTGAGTTCCATGGCTCATGCCCATAATCCCA GCACATTGAGAGGCCAAGGTAGACGGATCTCTTAAGTCCAAGAGTTCAAGACCAGTCTGG GCAACATGGCGAAACCCTAGCTCTACTAAAAATACAAAAAATTAGCTGGGCATGGTGTCA TGCACCTGTAGCCCCAACTACACGGGAGGCTGAGGTGGGAGGATTGCTTCAACCAGGGAG GTGATGGTTGCAATGAGCTGAGATCGCGCCACTGCACTCCAGTCTGGGCAACAGAGTGAG ACTCTGTCTCAAAACAAAAGGAAAAGAAAAGAAAAACAAAAAGAAAATGTTTCACTTGGT GATAATTGTTTTTTTCCTTCATTTGAATTTGTATTTTGCAATCAGCTTAAATTACTTTTA AAATAAAATGATATTTTTCAAATAAAAAGATGAACAATCTTAATGCTCAATCTGTTTACA TAAACCTGAAAAATATTAATAACCTTTAAGCCTACTTGCTCCACTTAATCTTTCCTCAGG AAATAATCCTAGAAGTCTTAACCACAGAGATGTTCCAGACTGTGTCATTTGTAAGAGTGA AAAAGTAGTAACAACCTACCTAATAAACAGGAATGCCTGAAGAAATTATGATATATTCAA TGATATATAGTGCATCCTTCATAATGAAAAAAATGCTACACAATAAACTTCAGTGAGAAG CTCAATATTCAAAATTATAGAGAGTATGATTAAAACCATATTATGTACAAACAAAACAGA AATCTGTAGCTGAAAAGATTGGAGGCAAATGTACTAAAATGAGTGGTGGAGCTCATTAAA TACTCATTTAAATGAGTATTTTAAAATTTAAATACTTAGAGAATTTCCCACAGCTTCTTT ATGAAAATGCATTAGTTTTACAAATTGAAACCAAAAAATAATAATAACAGAAATATCGAC ATAAATCCAATTTTACTAATTTGGCTTGATCACTGAAAAATATCAACTTTGACAGCTCAG TGATCAATACATAGAATAAACAAATGATTTAAAGCTTTAATCTAAAATGAAGAGACCAAC AGAATTAATTAAGTTTCCTTTGATCAATAAATTATTTTTATAATAAACAAAAGAATACAG GCGAAGCACAGTGGCTGTCACCTGCAATCCCAGCACTTTGGGAGGCCAAGGTAGGCAGAT CACTTGAGACCAGGAGTTCGAGACCTGCCTGGCCAACATGGCGAAATCCCATCTCTACAA AAAATACAAAAATTAGCCAGGTGTGGTGGTGGATGCCTACAGTTCCAACTACTTGGGGGA CTGAGGTGGGAGGATTGCTTGAACCCGGGAGGCGGAGGTTGTGGTGAGCTGAGATTGCAG CACTATACTACAGCCTGGGTGACAGAGTGAGACTGTCTCAAATAATAATAATAATAATAA TAATACATAAAGATATATGTATAGGAAGAAACACTTGCATAAATAGAATTTTAATGTAAA AACACCATATTTTATATTTATGATATATAAATACTTCTTTTTCCTATTTCCCTTTTTCTT ACAAAAAATGCAACTAGAACTATTTGCTTGGTTAATTATCCAATTTAAAAAAATAAATAT GAAAATAGAAATGTAGACAGATCACATCATAATGTAATTAGTTAAAAAGACATGCTTTGG AATTCAGATTAGGAAAGACAATATAAGAACAGTCCATCTATTTATTAGAGACTGACAGCT TATGGTTGACAATGGTGTGGCTGAATTTAAGTGAACTTAATTAAATATTACTTGATAATA CTTAACAGTAAAGTGATAGGGTGAAACAAATTGCAAAGTGTGGGCTAAGGTGAACTAGGC TTATACTTAATGTTTTTTAATTCTTTTACAAAAGATTATTGCAACAAAAAGATGTTAAAA TTTTTAGAAAGTGACAGTTGTATTTTTTTTTTCCCTGATAAACATGTAATCTAAGTAGTT TAAAACAACTAGGAAGATAAGAATCTGTCCGAAGTGACAGACTGATCAGGATTTCATCTT CACCATGCATTGTGGATCAGATCAGGCTTCAATACAAAACTCTACTGTGTACTAGCTCAC GACTTTGCATATATTTCATACCTTCTCTAGGTCTCAGTTTCCTTGTCTAAAAACTGTGGA TAATGTTTCCTAACTTAGAGCATTACTATATTTATCCTTGAAAAAAGACAGGATATAAGA GTAAGCTATGGTTATATTTTTGACAATTGAAAAGAGAATTTGGATTATGATCTTAATTTT ACCCACTCTTCACTCCACCCCCATCTCTACAAAAACAAAACAAAATAAATAAATAAATAC GCAGTTTCCAAGAATTGTGACATAATTTTATTTTCCAGAAAATGAAATCAGTGGATAACC ACCCCTTAGGAAATGAGCATAGAACAAACTCATTTTACATGAGTTAAAATGTAGTAATCA GAATGGAAAGAGGCAAGAACATATTACTTTAATGATGTATTTTTTTTCACTATTGAAAGT TGAAAAGTGTTATCAGAAATTCTCTGAAACAAACATATCTTAGTAGTCATTTCTAATATA AAATACATTCAGTCACTAATTTTTTGTGTTGTTTTGTATCTTTAGTTGAAGACAGGAACA CATAACCTATACTTTCAAAATACAGCCAGCCTAAAAAGGTAAATAAAATTTTTTATTTTG AAAAGGGAAAAATTTCAAGAAAAAAACTGTACCTATCTGTAGATGCTGGATAATGTTCAT TCAAATCTTTATAATACGGGAGCCTTTATTCTTTGAGAGGCAGAACTGGAGAATTAGGAC TTTGGAGGAAGAGACATCTGAGTTAGAATTCCAGCTTTGCCACTTAATAGTGGTGGGAGC TCAGGCACAGCAGCAGAACCCACTGGCTAGGTGACACAAGAGTTATATTCCCAGTCTCCT TCTCACCTGAAGCAGCCACAATGAAAAAGTTAAACACTGATTTTCAGAGCCTTCCCTGCA GTTAGGGAGAAGCTAGATATGTTGTATAGGTCTGACCAATTAAATGAAAACTGAAGTCTG GCAGCTTTTGTTTTCCTGGTAAAAGGGACAAAAAAATAAAAAATAAATTTTAAAAGAAAT TTTTTTACTTATTTATTTCTTCTTGTGAGACAGGGTCTTACTCTGTCACCCAGGCTGAAG TGCAGTGGCACAAACACAGCTCACTCCAGCTGCAACCTTCCGGGCTCAAGAAATCCTCCT GCCTCAGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACTGCACTCATCCCAGGTCT GCTTTTTAACTACCCTTATGAAAACTACCTGCCCTCCCCAATCTCTTCCTTCCCATTCTC TTCCTCCCTTAAACACAGACATGTGGTCTGTAGAATCAGCAGCCTTACTGTACCATGCAT GACTCAAGAAGCCCCAAGCCTCATGTTGATGTTAAAGCATAAAGCATTGTCAAGCTGCTA AAACAACCCCAGTAGCCACTAACATTCAGGATTCTCACGCAAAAAAAAAAAAAAAAAAAA AAAAAAAAGTCTCTATCTTTTTAAGCCACAAGTAGACAAGTTTTCTGCTATTTGCAATTG ACACAAGTCTAAATGATTTGGAAAGTCACAAATTCTGAGAATCACCTTCCTCATCTATTA AATAAGGGTGATGCTAGTAAGACGTATGTAAAGCATAGTATCTGTCTGACACATAGAAAA GGTTCAATAATGCCAGCTGTTGTGATAATGATGACAACTTTAATTCTCACACCAACCAGT ACTTTGATAGCACTTTGGGGGTAAGTACTATCTTCAACCACTTTAAAGACAAGAAAATTA AGGCTCCAAAGTTAAGCAACTTGCCTAAGATCACACAATTAGTTAGGAGTAGAGCCAGGA TTCAAATCCAGAAATCTTTCCAAGGCCATGATCTTAACTAGTATTATGCTTAGAAAAGTG ACTGAGTACAATTAAGACTTAACAGCTAATAAATGTTGGCTATAATGATTATGACAACAT AGCCAACTATGAAGACAAGAACAGGCAGAAAATGCCCTATAGTTTTCAAATCTAGAAAAC AATAAATTCTCATTTAATTTGACATTGATTTTGTTTGACATTGATTTTATTTTTCTTAAA ATTGAAATGGCTCTCATTTCTTCACTAAAACAGGTTACTACAGCCTCTTCACTGGAGGTT AACTTCATCCCTTTGTAACACCAAAGGAACTAAGAACAGTATATTCAACCAATAATTGAA ACACCCTACCAATAGGTAAATGACTTGGTGACTCTTGTCCATCAAAAAAGTAAGCAATGA GTATTTATTGTGAACTTATACTCTGCAAGGCACTATGCCGGACATTTAAAAATTATTTTC TCCAAAATATGCAGCACATGTTGATTTTCTTAAAGTGACTTAAGATTCCTTTGGAGGGAA AATTTAATAACAATTTAAAACATTAGGAAGATGCTGCTGCTGCTACCAGTCATCAACACC ATCGTCACCATCACTACCATTACTATTAATAATAGAATTCATATCACAAATCAACATATG CTAAACTTTACTTTTGGAATGCTTTGCTTCAAACTTCAGATGTCCTCTTCAGTGAAATAA ATGAAACAAAGAGCTTTAAAAATTCATGCTGGGTCGGGCGCAGTGGCTCACACCTGTAAA CCCAGCACTCTGGGAGGCCGAAGCTGGCAGATTGCTTGAGTTCAGGAGTTCAAGATGAGC CTGGGCAATGTGGTGAAACTCTGTCTCAACAAAAAAATACAAAAATTTGCTGGGCATGGT GGCATGCACCTGTAGTCCCAGCTACTTGCAGGGCTGAGGTGGGTGAATCGCTTGAACCCA GGAGGTGGAGGTTGTGGTGAGCTGTGATCACTGCACTCCAGCCTGGGCAACACAGCGACA CCCTGTCTTAAAAAACAAAAACAAAAACATGCTGAAGACACAGTATTTAAAAAACAAGCT AAATTCAAAATTAAAGTTTCTAAATAAATTACGTTCAGGAAACAGGCAAACTAAAATATT TGCAATTGCAGTTAGGAAAGATATTTAGTTTCTCAAATAGATTTTGAGATTTAAAGAGTT TGTGTTTAGCTGTTAACTTTCAAACTAATATGATGTATTATCATTCTAGTAAATAAAAAA AGTAAAATAAAAACTGAAACAGAATGGTAAGTAAAATAGAAGTTTTGAGGTAAGACTAAC TCTAGTAAAAATGCTGAGTCTGAAAATATGTACGTTTACAGCAATATATTTTGGAAGCCG AGTAACTTAAAATCGTATCTTCCACACTGAAAGAGGTATAGCATAACAAAGAGTTGACAC TACTATAAGTAGATATAAAAGAAATGCTTTCAAGGAAATCACATCAAGGAAGGATTGGTT TGCTTAATAAATTCAAAAATGACAGAGAGTAGCATAAAATCCACATGAACATTATAATAT GCTCAATCAGTTCTAATTAAGGATTTAATTATACCTATTTGATATCTAATTTGCATTTTT CTAAAGGAACACGAAGTATTCTATTTTAGGTCCAAAGTTAAGGCTCTGGGCAGGGTGCAG TGGCTCATGCCTGTAATCCCAGCACTTTGGGGGGGCCAAGGCAGGTGGATCACTTGAGGT CAGAAATTCAAGACCCGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAGTACAAA AATTAGGTGAGCATGGTGGCGGATGCCTGTAATCCCAGCTACTCAGGAAGCTGAGGCAGG AGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGTCAAGATCGCACCACTGCATTC CAGCCTGGGCAACTGAGTGAGACTCCATCTCAAAAAAGAAAAGAAAAGAAAAGAAAGAGA TGGTGGAGCCAAGATGGCCAAATAGGAACAGATCCGGTCTACAGCTCCCAGCATGAGCGA CGCAGAAGACGGGTGATTTCTGCATTTCCATCTGAGGTACTGGGTTCATCTCACTGGGGA GTGCCAGACAGTGGGCGCAGGACAGTGGTTGCAGCGCACCGTGCGTGAGCCGAAGCAGGG CGAGGCATTGCCTCACTCGGGAAGCACAAGGGGTCAGGGAGTTCCCTTTCCTAGTCAAAG AAGGGGGTGACAGACAGCACCTGGAAAATGGGGTCACTCCCACCCTAATACTGCGCTTTT CCGACGGTCTTAAAAAACGGCGCACCAGGAGATTATATCCTGCACCTGGCTCGGAGGGTC CTATACCCACGGAGTCTCGCTGATTGCTAGCACAGCAGTCTGAGATCAAACTGCAAGGCG GCAGCGAGGCTGAGGGACGGGCACCCGCCATTGCCCAGGCTTGCTTAGGTAAACAAAGCA GCCGGGAAGCTCGAACTGGGTGGAGCCCAACACAGCTCAAGGAGGCCTTCCTGCCTTTGT AGGCTCCACCTCTGGGGGCAGGGCACAGACAAACAAAAAGACAGCAGTAACCTCTGCAGA CTTAAATGTCCCTGTCTGACAGCTTTGAAGAGAGCAGTGGTTCTCCCAGCACACAGCTGG AGATCTGAGAACAGGCAGACTGCCTCCTCAAGTGGGTCCCTGACGCCTGACCCCCGACCC CCGAGCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACGGCCA GGTACTCCTCTGAGACAAAACTTTCAGAGGAACGATCAGACAGCAGCATTCACGGTTCAA GAAAATCCACTGTTCTGCAGCCACCGCTGCTGGTACCCAGGCAAACAGGGTCTGGAGTGG ACCTCTAGCAAACTCCAACAGACCTGCAGCTGAGTGTCCTGCCTGTTAGAAGGAAAACTA ACAAACAGAAAGGACATCCACACCAAAAACCCATCTGTACATCACCATCATCAAAGACCA AAAGTAGATAAAACCACAAAGATGGGGAAAAAACAGAGCAGAAAAACTGGAAACTCTAAA AAGCAGAGCGCCTCTCCTCCTCCAAAGGAACGCAGCTCCTCACCAGCAACGGAACAAAGC TGGACGGAGAATGACTTTGACGAGTTGAGAGAAGAAGGCTTCAGACGATCAAACTACTCC GAGCTACAGGAGGAAACCCAAACCAAAGGCAAAGAAGTTGAAAACTTTGAAAAAAATTTA GACGAATGTATAACTAGAATAACCAATACAGAGAAGTGCTTAAAGGAGCTGACAGAGCTG AAAGCCAAGGCTCGAGAACTACGTGAAGAATGCAGAAGCCTCAGGAGCTGATGCGATCAA CTGGAAGAAAGGGTATCAGTGATGGAAGATGAAATGAATGAAATGAAGTGAGAAGGGAAG TTTAGAGAAAAAAGAATAAAGAGAAACGAACAAAGCCTCCAAGAAATATGGGACTATGTG AAAAGACCAAATCTATGTCTGATTGGTGTACCTGAAAGTGACGGGGAGAATGGAACCAAG TTGGAAAACACTCTGCAGGATATTATTCAGGAGAACTTCCCCAATCTAGCAAGGCAGGCC AACATTCAGATTCAGGAAATACAGAAAACGCCACAAAGATACTCCTCGAGAAGAGCAACT CCAAGACACATAATTGTCAGATTCACCAAAGTTGAAATGAAGGAAAAAATGTTAAGGGCA GCCAGACAGAAAGGTCGGGTTACCCACAAAGGGAAGGCCATCAGACTAACAGCGGATCTC TTGGCAGAAACTATACAAGCCAGAAGAGAGTGGGGGCCAATATTCAACATTCTTAAAGAA AAGAATTTTCAACCCAGAAGTTCATATCCAGCCAAACTAAGCTTCATAAGTGAAGGACAA ATAAAATCCTTTACAGACTAGCAAATGCTGAGAGATTTTGTCACCACCAGGCCTGCCCTA AAAGAGCTCCTGAAGGAAGCACTAAACATGGAAAGGAACAACCAGTACTAGCTACTGCAT AATCATGCCAAATTGTAAAGACCATCGAGGCTAGGAAGAAACTGCATCAACTAACGAGCA AAACAACCAGCTAACATCATAATGACAGGATCAAATTCACACAAAACAATATTAACCTTA AATGTAAATGGACTAAATGCTCCAATTAAAAGACACAGACTGGCAAATTGGATAAAGAGT CAAGACCCATCAGTGCGCTGTATTCAGGAGACCCATCTCATGTGCACAGACACACATAGG CTCAAAATAAAGGGATGGAGGAAGATCTACCAAGCAAATGGAAAACAAAAAAAGGCAGGG GTTGCAATCCTAGTCTCTGATAAAACAGACTTTAAACCAACAAAGATCAAAAGAGACAAA GAAGGCCATTACATAATGGTAAAGGGATCAATTCAACAAGAAGAGCTAACTATCCTAAAT ATATGTGCACCCAATACAGGAGCACCCAGATTCATAAAGCAAGTCCTGAGTGACCTACAA AGAGACTTAGACTCCCACTCAATAATAATGGGAGACTTTAACACCCCACAGTCAACATTA GACAGATCAATGAGACAGAAAGTTAATAAGGATACCCAGGAATTGAACTCAGCTTTGCAC CACGCGGACCTAATACACATCTACAGAATTCTCCACCCCAAATCAACAGAATATACATTT TTTTCAGCACCACACCACACCTATTCCAAAATTGACCACATAGTTGGAAGTAAAGCTCTC CTCAGCAAATGTAAAAGATCAGAAATTATAACAAACTGTCTCTCAGACCACAGTGCAATC AAACTACAACTCAGGATTAGGAAACTCACTCAAAACCGCTCAACTACATGGAAACTGAAC AACCTGCTCCTGAATGACTACTGGGTACATAACGAAATGAAGGCAGAAATAAAGATGTTC TTTGAAACCAACAAGAACAAAGACACAACATACCGGAATCTCTGGGACACAGTCAAATCA GTGTGTAGAGGGAAATTTATAGCACTAAATGCCCACAAGAGAAAGCAGGAAAGATCCAAA ATGGACACCCTAACATCACAATTAGAAGAACTAAAAAAGCAAGAGCAAACACATTCAAAA GCTAGCAGAAGGCAAGAAATAACTAAAATCAGAGCAGAACTGAAGGAAATAGAGACACAA AAAACCCTTCAAAAAATTAATGAATCCAGGAGCTGGTTTTTTGAAAGGATCAACAAAATT GATAGACCGCTAGCAAGGCTAATAAAGAAGAAAAGAGAGAAGAATCACATAGACGCAATA AAAAATGATAAAGGGGATATCACCACCGATCCCACAGAAATACAAACTAACATCAGAGAA TACTATAAACACCTCTACGCAAATAAACTAGAAAATCTAGAAGAAATGGATAAATTCCTC GACACATACAACCTCCCAAGACTAAACCAGGAAGAAGTTGACTCTCTGAATAGACCAATA ACAGGCTCTGAAATTGTGGCAATAATCAATAGCTTACCAACCAAAAAGAGTCCAGGACCA GATGGATTCACAGCCGAATTCTACCAGAGGTACAAGGAGGAACTGGTACCATTCCTTCTG AAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAACTCATTTTATGAGGCCAGC ATCATCCTGATACCAAAGCCTGGCAGAGACACAACCAAAAAAGAGAATTTTAGACTAATA TCCTTGATGAACATTGATGCAAAAATCCTCAATAAAATACTGGGAAACTGAATCCAGTAG CACATCAAAAAGCTTATCTGCCATGATCAAGTAGGCTTCATTCCTGGGATGCAAGGCTGG TTCAATATACTCAAATCAATAAATGTAATCCAGCATATAAACAGAACCAAAGACAAAAAC CACTTGATTATCTCAATAGATGCAGAAAAGGCCTTTGACAAAAATCAACAACCCTTCATG CTAAAAACTCAATAAATTAGGTATTGATGGGATGTATCTCAAAATAATAAGAGCTATCTA TGAAAAACCCACAGTCAATATCATACTGAATGGGCAAAAACTGGAAGCATTCCCTTTGAA AACTGGCACAAGGCAGGGATGCCCTCTCTCACCACTCCTATTCAACATAGTGTTGGAAGT TCTGGCCAGGGCAATTAGGCAGGAGAAGGAAATAAAGGGTATTCAATTAGGAAAAGAGGA AGTCAACTTGTCCCTGTTTGCAGATGACATGATTGTATATCTAGAAAACCCCGTTGTCTC AGCCCAAAATCTCCTTAAGCTGATAAGAAACTTCAGCAAAGTCTCAGGATACAAAATCAA TGTGCAAAAATCACAAGCATTCTTATACACCAATAACAGACAAACAGAGAGCCAAATCAT GAGTGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTAGGAATCCAACTTAC AAGGGATGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTCAACGAAATAAAAGA GGATACAAACAAATGGAAGAACATTCCATGCTCATGGGTAGGAAGAATCAATATCATGAA AATGGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATCAAGCTACCGAT GACTTTCTTCACAGAATTGGAAAAAACTACTTTCAAGCTCATATGGAACCAAAAAAGAGC CCACATCGCCAAGTCAATCCTGAGCCAAAAGAACAAAGCTGGAGGCATCACGCTACCTGA CTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTACTGGTACCAAAACAG AGATATAGATCAATGGAACAGAACAGAGCCCTCAGAAATAACGCCGCATAGCTACAACTA TCTGATCTTTGACAAACCTGACAAAAACAAGCAATGGGGAAAGGATTCCCTATTTAATAA ATGGTGTTGGGAAAACTGGCTAGCCATATGTAGAAAGCTGAAACTGGATCCCTTCCTTAC ACCTTATACAAAAATCAATTCAAGATGGATTAAAGACTTAAATGTTAGACCTAAAACCAT AAAAACCCTAGAAGAAAACCTAGGCATTACCATTCAGGACATAGGCATGGAAAAGGACTT CATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAATGGGATCTAAT TAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCATCAGAGTGAACAGGCAACCTAC AGAATGGGAGAAAATTTTCACAACCTACTCATCTGACAAAGGGCTAATATCCAGAATCTA CAATGAACTCAAACAAATTTACAAGAAAAAATCAAACAACCCCATCAAAAAGTGGGCAAA GGACATGAACAGACACTTCTCAAAGGAAGACATTTATGCAGCCAAAAAACACATGAAAAA ATGCTCACCATCACTGGCCATCAGAGAAATGCTAATCAAAACCACAATGAGATACCATCT CACACGAGTTAGAATGGCAATCATTAAAAAGTCAGGAAACAACAGGTGCTGGAGAGGATG TGGAGAAATAGGAACACTTTTACACGGTTGGTGGGACACTAGTTTAACCATTGTGGAAGT CAGTGTGGCGATTCCTCAGGGATCTAGAACTAGAAGTACCATTTGACCCAGCCATCCCAT TACTGGGTATATACCCAAAGGACTATAAATCATGCTGCTATAAAGACACATGCACATGTA TGTTTACTGCGGCTCTATTCACAATAGCAACGACTTGGAACCAACCCAAATGTCCAACAA TGATAGACTGAATTAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCATAA AAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAACTGGAAATCATCATTCTCA GTAAACTATCGCAAGAACAAAAAACCAAACACCGCATATTCTCACTCATAGGTGGGAATT GAACAATGAGAACACATGGACACAGGAAGGGGAACATCACACTCTGGGGACTATCGTGGG GTGGGGGGAGGGGGGAGGGATAGCTTTAGGAGATATACCTAATGCTAAATGACAAGTTAA TGGGTGCAGCACACCAGCATGGCACGTGTATATGTATGTAACTAACCTGCACATTGTGCA CATGTACCCTAAAACTTAAAGTATAATAATAATAAAATAAAATAAATAAAAATAAAAAAA TTAAAAAAAGAAAGAAACCTAACTGTGATATATTTATGGAAAAATATTTTATTAAAAATT AAAACAAGGTAAGAACAAAGCATCATGTTTTCAAGTATAGGACAATGTTGAACCTAAATA ATTCCTAATATATTCAATAAAAGAAAAATGGATATGTATAAATGGAGACATAAAAAACAC AAATGTCATTTATAGACACATAAAAGTATTCTTTAATTATTATAGTGCTGTGATTTTTAA AACAGACAGCTCCAAAATAAGCCTTTTTGAACAATTCTGTTCATCAGACTCCTGGGTAAA TGAATTTCTACTGTACACACTGACAGATACAGGGTTAGAACCTAGATCTCTTGCCCTCCA CTCCTATGTTCTTCCTGTTACTTGTCTTGCTTGACTTCCTTGCACATGCCAAAAACTACT GTATCTGCTTCCTGCCATTTTTACCCTCTAAAATTGTATAAAGCACTTCCTAGAAGAATA TAGAAAAAGAACAGAGAAGTAGAAGGAGAATCAAGAAAATAAAGGTATGTGACAATTTCT GAGAAGGGAATAGCCAATATTATTGAATAATACAAAGCAGTTAAGCAGAAACTAGTGGGC AGGTAACCAGATGTCCCTGATGAGTTTAAGAGGGTGCTTTCAACAAGTATAATGGTGAGG GCAGAGCCTGGTGGGCTGAACTGATGAATGAACGGTAATTTGGGAATGGGAAAAGTACAA TAGTTTTAAGGGGAAACATGCTAAAATGTTTGCAATCTTACCAAACTATCTAGAAAAAAT GATATAGAAAAAATTTAAGGTAAGAAATAGGAAATCCAGGGAGTATTAGCTTGAATCAGT TGAAATTTCAGATACTCAACTATTTTGACGTTAAAAGCTGCAATTTTATACGGTTTAAAC TAAGGTACAAACTTGATTTCAAGAAAGGAGATAAGGTTATCTTCTAAGGACATAGAAGCA AAGAACAGATGCCTAAGAGTGAAGTAGGTAAAGTAATAAGAAATCTACGAGAAATGAATG AAAGAATTTTAGAGTCCTGAAGTTGAATAATAAGAATAATATACTTGGCAAAGCTACACT GTTTTTCTAAAAGGATCCTGTTATTTTTACATTTGCATTTCACTTTTAGAAATTTAGCTT TTTTTCTGTAATAGGATGCCTGAACATGAACCCCGCAACATTTCTTCAAGGCAGGCACTC TCACTTAATGTGGTACAAACATAACTGCAGTGATGCTGTTGCCTTTATATTTTGTTTTGT TTTGTTTTGTTTTTGCTGATAAAGGCAGAAGATCAAGGCACTTAGAGCCTAATATGAAGT TGCTATTAACAATCCCAGGTCTACTGTTATTCCACAACCTAATTTCTCATATTTCCAATC CCATGTCACCAAATGCCTACAGAAAAATCACAACATGACCAGGCACAGTGGCTCACACCT GTAATCCCAGCAGTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGCTCAAGAGTTCAAGA CTAGCCTGGGCAACATGGTAAAACTCCACCTCTACCAAAAACACACACAGACAACATTAG CCAGGCATGGTGGCAGACGCCTGTAGTCCCGGCTACTCAGGAGGCAGAAGCACAAGAATC GCTTGAGCCCAGGAGGTGGAGGTTGCAGTGAGCTGAGATTGCACCACTGCATTCCAACCT GGGTGACAGAGTGAGATCCTGTTTCAAAAATAAATAAATAAAGATAGAATAACCATAACA TGTCTAAAACAGAACTCCTGCCCTTTGAACAGTTCTCTACCCCACTTCCCTACGGCTGTG ACCTCTATTTTTCTAGTCACCTGGGCTAGAAACCTTTAGCATGAGTTACCGAGTCCTATC AGTCTTTCTCTGAACAGGCTCTTCTAGCTTTCTGTTCCCATCTCTTTCCACTCTAGTCCA GCCTCTAATCACCTCTTGTCTGGATTACAACAGTCTCAGAACTGGTCTTATGGTATCCAC TCCATCTCACACATCACTACTAATGTCAGCATACAAAAATGCCAATCCCCAAACACCACC ATCATAACTTTTCACCCTGAAATTCAGACTTATCTATAAGGATACTAGCCTATCTAGCAA AGCAAATATTTCACCACTCCCTAAAACTTCCATGTCATGGAATCTTGACCACTGTGGTCA CTTTAAATGCATACACAGCAAAAAGAAAAAGAATAGAATAGAGGAGCAAAGAGAATGGAA ACAAAGACAATGATTAGGAGAAAGTCACTGTGGGATAGGCGCAGTGGCTCATGTCTGTAA TCCTAGCACTCTGGGAGGCCGAGGCGGGCAGATCATGAGGTCAGGAGATTGAGACCATCC TGGCCAACATGGTGAAACCCCATCTCTACAAAAAAAAAAAAATTCAAAATTAGCTGGGCA TGGCGCGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTAGGAGAATTTCTTGAAGCC CAGAGGTGGAGGTTGCAGTGAGCCAAGATCATGCCATTGCACTCCAGCCTGGTGACAGAG CAAGACTCCATCTCAAAAAAAAAAAAAAAAAGTAACTGTGGCAAATTCAGGTACAAGGTA CAAGATATCCATGGCTGGAGAAAAGCCCTAATGGTAGAGACAGAGGAAAGGGCAGATTTC AGTGATAATTAAGAGGAAAGCTGATTGAGTGGATGCAGGAGGAAGGTTGTAATGAAGAGA AATGAGTCTATTCTGACTCTTGGCTTTCTGGACTATATGGCTGGATAGAGTTTAATTCAA TTAACCAAAATAAAAAATAGTTTGAAATTTGTCTGAAATTAGCAAGGCTCTCTTGCATGA GATAGAAATAACTACTTAAGAAAATGGAGTGTCAGCAGCTTAAAAAAAGAACTTTTGCCA GATTTGAATTAATAGAGACAGAAAGAGAAGCAGTATGGACTTTTAAAGCCAAAGCTAGCA CTAGGCCTAGCAAAGAGCAGCCACTTGATAAATGTTTACTGAAGTAGCTCAAAGCTGCTA GCAGTTGACTCAATGTATGGATAAGTAAGGAGACAAGAATTTTAGATACCTAGAATCACA GTTGGAAAGAAAAAAATAAAGGTTACCTTGGAAGTATACAGAAAATCTAGGTTTAAGTAG TGTCTAATAATATATTAGAGATGAAAATATTTTTAACACTGAAAACAGAGCAGAGAAAGA TGTTTCCATTTTCTTAAATCTTGCTGTCATATATTTTGTGTTTTTATAGTTACTAAATTT TTGTATTAAAAGTTAAGCTTTGTTCACACACAGAAATTAAATACGTAAAATGCATACACA AACTCTGTACACCTCCCTCTAAAAGGCAAAGCCCAATTCCCTTTCTCTTGAGTATAGGCT GGGCTTTGTGACTCACTTGGTTATTAACCAACAGAATATGGCAGAAGTGACAATGTGTGA CTAGGTCATAAAAGGCATCACCACTTCCTCCTTGCTCTCTCTCTCTCTCTCTCTCTCTCT CTCTCTCTCTCTCTCTCTCTCTCTCATCACTTACTATGGGGGAAGTTGCTATGTTGTGAG GGCACTCATGCAGCCCATCAATGGTGAGATTCATGTGCCAAGGAACTGAGGCCTCCTGCC AATAACCAGCACTAACTTGCCAGACATATGAGTGAGCTACCTCAGAAGCAAATCCTCCAG CCCCAGTCAAGCCTTCAGATGATTACAGCCCTGGCTAATATCTTGACTGAACTTCATGTG AGACCTTGAGCCAGAATCATCTAGCTAAGGCATTCCTGGATTCCTGCCCCACAGCAATTA TGTGAGATAATACATGTTTATTGTTTTAAGCCACTAAGTTATGAAGTAATTTGTTACACA GACATAGAGAACAGTCACACAAAGCTCATTCTCAATTCTGTGCCATTCCTCATGCCATTT TCCCCAGAGATGTCCTTTCATTATCCATCCCAACACTCCCTCTCTATCCTTCGGTATCTA ACTGAAGTTTCATGTCTTTGGGAGGCACTTTTTTGTCTATGAAACCATCTCAACTTTCAT TTCTCTGGCTTCTCCTTTGAAGAAGCCAGATGCTTGACCACATCATTCATTTAGTCATTT ATTCATACATTCCTCTGTGTTACTGTGCTATACGTTTATATCTTTCCTCCTAAAGATGAA GATGTCATACAGTTTTTAAAAACTGCATTAAGCACATTATGATTAAGGTACTCAATAAAT ATTTGCTGATAAAATTAACAAATCTCACACACACTTATAGACACATACCCTGAAAGTGTA ATTTCAGTAAGTAGCATAAAGTAGTGGTTAACAATATAGAGAAGCTACTTTAGCTCACAT CTGCATACTTATTAGCTGCTGTCCCTGGGTAAGTTATTTAAAGTATCTCTGTAAGCCTTA GTTTCTTCAGTGTTTTTAAATGAGAATTCTAACAGTATCTTAGAGTAATAACAAGGTTAA AGAAAATAATGCATGCAAACCTCTTAACAAAGTACCTAGCATAGAGTATTCAACAAATGT TAGCTATTATTGTTCTTATAATTAATTACAAATCACAAAATATGTGCTGAAATTCTGAGT CCCTATGAGTCTCTAGATGTTATCAAGCAGCAATCTAAATTAAGACAAAATTCAAAAGAG AACTCAGACCTTCTTTTAAAATAGCTTTTAATTCTTAAAAAATCCACTTGTAGGTCACTA GAACTACAGCCTGAACCAATTGTAGGACTGCAGCCCTGATTCTTTCTCCTCTCTGTCCTA TTAAGATATTACCTTCAAAGCTTTTGTGGGAACACTTAATTGCTTGCATTCCTTAACATG CAGCTACCAAAGTAGTTTCCAGATTCACTTTTGACCTTCACAGTCCTGAGAAGGCATATG AGGCAAACTTCCTAGAGATGTAAATTTAGACAATCTCTGGAATGATAGAGCTATACATAT GTGAATATGCTACATAAAGCAAATCCATTTTGCATGTCAATTAAAACAGAATCCCATTGA ACAATCAATCCAATACAACAAATCAATCCAAAAGAATTTTGTTATGGCATGTATCCAAAC AAGAAAAAACCCCTCCAATGCTATTCAGTCTGAATTACATGAGTTTCATGAACTTGGAAC ATCTCTAAGATCATACTTTATAATTTGATCATATTTGAACATATTTTAAGGTTTCCTATT AAAAAGCTAAATATAACGGATGCTCTTCTATCCTAAAAAAGACTGAAGAGATCTGTTAAA GAAAAACTAGTAGAATGATTTTAAATCACCAACCTATATAAAAACATGCATGCTTTTTTA ATGTGTTCCATGTCCTCTGCAATAAAATGACCCACTTAATTCAAATTCTTATTTTCTCTT TTCCCCACCAATACACCTTGAAAACTTTAGTTTTTGAAACATCCAACATACATTCCACTC TTTATCTGACCCTACATATCACACAATCTGAAATAGAAACAAAGATGGGAAAATTAGCTT GTTTATTCCACCTTAGTGTCAAACAAAAGTACAAATAAGATTCAGTGCACGTGCCAGTTA CCTTAGAGCTGCCAATCATGCTTGTTTTGAAACCCTTCAATTTTCAGAGCTGTCAATCCT GTGTTTTATGATAGAGAGCCAGCATAGAGACAATGCTTTAAAAGACACAATCCTCATTAA CACATTAGTAAACGGACTTTACTTATAAAACTGGACTTGAAGATTTTACAGAAATGTTTA CAACTCTCGAAAAATCAAAACTAAAATACAACTTAATGAAATGAAAAGATTTGGAGAATT TGGCTCTTTGACCAAAGCAACAGCATAGTTTAACCACAGGGATTTTATACACATATATAC AATATTATATTATAAAAAGAGAATGTTCCTGACTAACACTAATCGCAAGTATTATGACCT TGAATGGAAATAAGAGAATAAAAGTGATCTACATCCGGGCATTTTAATTTTTGTTTTTAA AGCAGGCAATAATATCAATAACACACTCCCCTTCTCTACCTCCCCAACACAACCCAACTC ACTACCCAGTCCATTCATGTCCAAAATGAAACATTATTCAAAATTTTTCTCTCTCACCAA CCACAACTATTCAGTCACCAAGACCTGTCTCTTCCACCTCCTAAACTGCTAAATGTGTCT CCTTTCTCCACCCTCAGATTTAATTCATATTCTCATCATTTTTTTCAGCAGCTTCCTTAC TAACTGCCCTCTCACATCCTTCTTCCGAAATATGCTCCACACCTCTGCCAGAATGATCTC ACTGAAACACAAAGTTGACCCACGTTCCTTGTTACAATATTTTAATGATTCTTTGCTACT TTGAAAATAAAATCCCAATTTTTTAGGACAATATGTAAATTCCTTGAAAATCTGGCTCCT GGTCATCTCCCCACTCTCCCATCACTCCTCCTAAACTTAAGCCAACTAAACCACTTGAAT TCCCAGAAGAGGCAGCCTCTCTCTCATTTAAAACTTGTTCAAGTGCTGCTCCTTCACCCA GAAACACTCTCACTTTCGGCACTTAGTATCTCCTACCCATCCTTTGCAACCCAGTTCTAT TGTTAGTTCCTCTGGGAAGCCTCTGACACAAGCAGATTGAACCATCGATTCCTTCTCCAT GCCTGTAGAATACAATGAACAGAACTTATATGATGTTATATTTATTGGTTTACTTCTCTA TCCCCCTGACCAGATCAACTCCCTGGAAGCAGGGATTGTCATTAGTCTGTATGTCACTAG CCTTAAATACACAGGTAGCACATAATAGATGCTCATTAAAAGTTTGGTGACTCAATGAAA AATCTTATCATGCCCAGTTCATTTAAAAATAAAATTCATAAAATAAGCAGCTTATTTCTT GAGATTGATAAAATGTTTTACCAGTGCATTACAAGGCATCCAAACTAATCAATGCTATAA AGCAATTCTTTGGGCTTAACAAGAGTTTTAAGAAATTTACTCATTTATTTGCAAATTCAC TATAAGAATTGGTACCATCTCAAGCAGGATTTCGGATTGAATAATTCCACCTTATTTTTG CTACTGCCCCTACTGGAGGTGTTAAAGTCTCAACCATGATAAATGCTCATGTCCAAAACA CTCGGCACCTTGATTGGTTCAACAAACACTGTTCTGATATGTGACAATCCCTATCAAGGG CATCAGTGAACAGGGAGTCGACATAGGCAAAACTCCAACCCAGTTACACTTCACTTATCA GGAAGTTAGTTATCTGGTGACATCAAGTAGCTACACAGCCCAGTGAGACCTAAACAGAAG GAGTTTAGGAGCTGTCAGAATACATGTTGAAGTCCATACACTAAAGTACCCACACTTTAC TCACAGAAGAGGCTGCTAGGTCCTTACTCAAACCCTAGTTGTTCTTATTTTAAGCACAAC AAATTTGATGACTGATCTCCCAAGTATAGGCATACTGGAAGAGGAAAATTAGGAGGTCTG AGAAAGCTATAAAAAGCAGACAAGGGCATAACAGCAGTAAAGGAGAGATAACACAAAACT GCAGAACTGGAGGGTTATATGGTTATGCAGCAATAATTCTGTATATTTTTATTATGATAC AATATAGAAATTAATGTTTATAATTATGACCCTGGGTCATCAAAAGCAAAAACAAAAAAA GGTTCAACTATTTTAGGTCTAACAAGGTTCAAAGAAAGTATATAATACATTTTATTAAAA GAACCAATAAACAATTAAAAATTAAGTATATTAGGTATAAATAGCCAATTTTCTATTATT TACACAATAAACTTTTTTGAAATACATCATTCCCAAATAACATGAGGCATACTGATATTA ACCAGGTCCTGTGACTAGAGGTCTTACCACAATTATGATACAGATCCATTACAAAACAAA GCCTAGACCTGATAGTTATTAGCTTATTGGGGGTTACACTATTCCAACTTACCATACTAT TTCCTAGTCTGTTCGATCTGAATAACAAAACACCATAAATGAGGGTATCTTATAAACAGC AGAAACTTCTTTCTCATAGTTCTAGAGGCTGGAAGTCCAGGATCAAGGCACAAGCATATT TAGTGTCATGAAGACCTGGTTCTGGTTCATAGATTAACTAACTAGCCAGTTCACTAATCC CACTCACGAGGGCAGAATCCTCATGACCTAAGTACCTCCCAAAAGCCCAGCCTCCTAACT ACATCACACTGGTGATTATGTTCCAACAAATGAATTCTGCAGGGACACAAACATTCAGAC CACAGCAACAATGGACACCATAACCAAAGATATAACAGACTACCTATGATTTTTTAACAG ACCTCCACAGAGCTTCACTGCCACACTGCCTTCAGGGTCCCTGGAATGAAACTGCTTCAT ATGTAAGACTGTTTTAGGAAGTCTTTATGATGCTTGAGTTACTATATATTGTATGATTTA GAGTGAAGCACAGCGGGGTGAAAAGAAAATTTGGATATACACAGCCCTAGATTTGAATCC CTGCTTTGTTAATCCCTAGTTGCATGACTGCAGCACATTATTTATGCTCAGAGACTCATT TTCTTCATTTGGGAAATGTGGATAATACCTACTATCTATGTTTGTTGTGAAGAATATATA AGACAATATACATAAAATACCAGTGTAGGTTTTTAAAAAGCTGTTAAGATTATCAGAAGG AAATCAGATGGAATATAGAAAGGAAACAATCAAGTCTGTGAAATTGTTTGCTGCATTAAT ATGACAGAAAAAAATGTCTAAAAACAGGTTCCCATGATGGGAAAAGTGCTCTGTATTTTT AAATTACCATACAAGCCCTCTGACTCACAGAAAGGTTCATGGTAAATTAGGTTAAAGACT CATAAAAAAAGTATACATGTACACAGCAAAAATATTAACTTAAAGCAGATTAATGCAAAT ATTCTAATATGGGGCCAAGGCGTTCTCTCTCAGTAGGGGGTCCACTCACTGAAGCTCTGC TCTTCCTCACATAACAATACCCACACTGCAAGGTCTGTGACTGCCAGGGCCAGTCATGTG AAAGTAGAACAAGAACAGAAAGACAATTGGAAAGCAATACCTTTCACGTTTTTATAATTT TTGTTTCAATCTACAGTTTTCTTGCACAATCTAATTCAATAGCAATTTCTTAAAAACAAA AAACTCTCTCCTTTCTGATTCAAGCAGCAGAGATGGGGGAAAAAAAAAAAACCAAAGTTT TCTGTTATGGAGTCTTTCTAAAACATTAAAGTTAGCATTCATAAGAACAAAAACCCTTTC TGTATTCAAATTTTATTAGTTTGTACAATATTCAAGTAAATTTCTTAATATAAACACATT CTGAAATGAGTACAACTAGGCCGGGCATGGTGGCTTAGCCTGTAATCCCAGCACTTTGGG AGGCTGAGACGGGCGGATCACTTGACGCCAGGAGTTCAAGACCAGCCTGGCCAACACGGC AAAACCCTGTCTCCACTAAAAATACAAAAATTAGCTGAGCATGGTGGCACATGCCTGTAA TCCCAGCTACTCAGGAGGCTGAGGCACAAGAATTGCTTGAACCTGGGAGGCAGAAGTTGC AATGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAACAAGACTCTGTCTCA AAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAACAAGCACAACTGAGCTTTTGCTAAACA TATACCTCAACTGGAAGAAACCAAAGTGCCTAGGTATAGTACAGGACTACTAATTTCTAA TGTTCCATGTGGTGTTGGTATCTGTCAGTGGGCTTTACAAAAGAAAAAGATGATGTCAAT TGATTTGACAAATCAGTTATTAAATGATAACTTCCAAAGAAGTTAATGCCATTCTGAGTC ATTCTGATTTGTCATATGTGATTTCTGACTTCAAGTCATAAGCTGATTTAAAAGAAAAAT ATAATAATTATAACTTTTGAGGCTGGTACTATAAGGTCCCATGCATGTCTCAAAATCTCT AAATATACGTATGTCTATTTTGCAACTCACTCTAAGTAGATCAAATTACTATTGTTCATG CTTAAGTACTATAGCTTAGATTCTGAATGCTACTATTAAGGTCATGTCTTTCTAAAATTA GTTTCTTCCTTTCCAAGTGTTTTTCAAACTTTTCTTATTTACAGTAGAAATACTCACCAC ACACATTAAACAAAATTGTCCCAGAGCTATAATACATAAAACAGATAAATGCAGGGCTGC TCTGAAAGTAGGGCCCAACTGCCCCTTTATCCCCAATAAGCAATATCTTATGCTTTTCTG CAAAACTCTAGGGCGTTTTGGTACAAAGACTAAAAACTGCTCCTTTAAACTATAATCAAA AATGAACATTAAAACAAAAGTTATAGAACTTAAAAGGCTATTATTTAGCTAATTAGAATA TTCATTAATCAAAATATTTTCTGATCCCTATTAGTTGTTATAAGTCTGAAATGCCAAACT TACTTATTAAAAGAAACAATAAAAAATTAAAACATTTGGCTAAACTGGATATTTCAATTA GTTATTTTTCATTGTATTTAATTAATCTTTAAACTGTCCTAAAGTAGCATTATTCAACTA CACAAAAGTCTGTATGAAGAGAAGAAAATAGTTCTCTAAAAGGATCAAAAAAAAGGGCAG GCTGATGAATGATGAACAGATTATGTAAATATTTCTCTTATTTATAACAATTTAAAATGT ACCAAAGCAGGAAGCTCTGCTATTATGGAGATTCAGCCTCCTAGAAGCTGCTCAGTCAGA GGCCTGACAGTATAACTGCAGAGAACACGTGTCCAGCCCAATAAGCTGTTCTACCTCGTC ATATAATCTAAACGTACAGGTACAAAAAGGGGAAGACCACAAACAACTGAGCTGGATCTC ATTACTTCCTTGTTCAGTGATAAAGACAACAGGCAAACATTTGAATTAAGTAGGTTCTTA CCCACAAATTTTGTTTTAGATATAAGTAGGAGTAATCAGTAACCAAAATAGTAATTATGC TGACCTGACAATTCTCAATAATATTTTCAAAGCATAAGTGACAGATCCCTATAAGAAACC TAGAGAAGGGTTTTGGAAAGAACCTAGGCATTTCTACGTGTACAAATGAAGATCTAATAA TCATTCTGTGAAGAGTATAAACCTTCATTTCATGACAGATTAAAAACTGGAGAACATGAA ATTTGCTATGTTAAAAAGTTTCTCTCCAAAAAACAATGTATGTCGATAAAGAGCTGGAGT TGTTATCTACATAGCCGTAAGGGTATGTACATAGGATATGCAGGTAGAGAAAATAAGTAA TCAAACTACTGATGTTAAACCTTGGCTGAAGATTGGGCACAGTTAGAAATAACATTATCA GTCTGTAGGACCAAAGAGGAAGCTGAAGAGAGAGAGCTTCAGAGATAGCTGAAGCCTTGA CTCTTATCTTTTTTTTTTAAAGTCACTTTGATGACATTTCAGACTTACAGAACTAGAACT AGAAGTCAAAGGCCTTTTTTGACTACTGTTATTTTCCACTCACCAGGCACTCTGTCACCA TATTATCCATTTTTACTTATGTAATTACCAATATTTTAAATTGATTCATGTACTTGTTTA CTATCTATGCCTCCTTCCCCCATTTGCATATGCACTTCAAGAGAGCAGAGAACTAGTCTG TCTGGTTTACCAGTCTTTACAACAGTACCTGGCAAATTGAAGAGGTCTAGTAAGTATTTG TTGAATGAATGAGTGAATGAATGAATGAATGAACAAATCAACTCCTGTAGCACTTTGGCT CCTCCCTCTTGATGATCCTCATTCATGAATGTATTTATTTTGTGACTCCTTTGAAGTTTA AATGGGTATTTCTGGTAAGAGTAACTGGATATTAAGCAGGTGGTTTCATGGAAGCAGGAA TAGAGAAATTACTACAGATAACTACAGAACAAAGAGATGTAGGCATATAACTCTCCTAAG TACCTTTAAAAAGACTCTAATATAGTGACTGCTCCAAAGACTAGAGAATTTACTTGCAAA ATTACTAAGAGCCACCCCGTCTCCCCTCAAAAAGCTTTTATGACTGCTTCACTGGGGGGA GAACAGACAGAGATGGAGGTTTCAAGAAAACAATTTATATAATAGAATGTGTGCATATGT GGTATATATTTAGTTTTAAATAAAAAATTAAGATTTAATAAATGTTGTAATAGATGCCAG TATTTAACCATTTAAAGCTATACTACACATAAAACAAATTCAAATCAGACTATACTACTC ATTAGAAAACTAATCGCAAATCTGATACTTAAAAATCTGTGACTTAAAGCCAAGCATGGT GGTACATGTCTGTAAGTCCCTGCTACTCAGGAGGCTGAGGTGGGAGGATTGCTTGAGCCC AGGAGTTCAAGTCCAGCTGGGGCAATTTAATTCTAGATCTCTAAGGCATTCTGAATATAT TATGTTCAAGAATATAACATAATCACAAAAGTGATGTTTTAAATTTTTAATTCAATGAGA AAAAAGAACAGTGCCGACAAAAGAATATCCCCAAAGAAATAAATATCCATGAAAGAGATA TGATTAACGGAATTCCATCCTCACATATAAAAAAAGTATATGACTAGTATTTGTAATTTA TAATAAACTTGACTAAGCAGTTGAACATCTGCTGAGAAATATCTTAGCAGAGTTGTCACA AAATATATCTTTTTATAAAGTCAATACCTGATTCTCCAGTTGCATGTTAGGTCAGCTTGT AAGAATAAGACAGGCACTGCGATGGACAGCATCCATGGTAGATGATCAATTGTAAGGAGG GGACTAAGGATTTCTTTGTGTAAAATAAAAGAGCACTTTATTTTATAATTACTATATATT TTCTACTAATGAAAAAATGATCTGCTACAGCTTCTGCTGATAGTACCTAAGAGCTGAGGA TACCTCTCTTAAAGGGTAACTTTTGTATCACATATCTTCTTACTTGCCTCCTTCATAAAC CCTCCTTAAAAGGAATTCTTGAGGGATGTCATCATTAGGTCACCAGGATTTTAATAATAA CAATGCAATGAAAATAACAATAACAATAGTAGCATTTGTTTACCATATGCCAATCACTTT TCTAAATTTTTAGACACAATAACTAATTGAATTCCTTCAGTAGCCGTTTACATAACAGAT ACTGATTACAGTATTAAAATCTGGATTGACAGACACATCCTACTTAGAAATTTCTTTGAG TCTCCCTACTTTTGAACTAAGCTTGTATGATATTTGATACACCAATTCAAGTCATGCTCA AGCCATTCCTCTCATGCCAGGGAGCACAGTCTTTCAGTTGACACCTGGTTTATACCACTC ATCTTGTTAAAACACTGTTCAGCTTCTGGTTATCTAAGGGAGAGGTGTGCTGCAGCCAGC TAATACCAGCTTGTGAGAAGCACTGTGCACACATCTTCCCAACTCTGCATTCGGTGACAT CATGTTGGTGACTTGACATTGGCCATGCTGGGAGTATTTCACATTACAGAAATTGGGGCT TTTTTTTTTAATCAACTAGTTGTTAAATATTTACTCATATATCATTAATCTGAGGAAATG TGTATTCTGTTAAGTTTGTCAGACCCTATTCAGATTCAGGTAGGACAAGCTTATGTCTCT AAATTGGGTAAGACCAATTATCAACGGCATCTTTAGATATCCAGCTCTCAGGAGAGAGGC AACTCGTTCTCATAATTGCTCTCCTAGGTCTACAGTAGACTCTTCGCCTTTCATTTCCAC AATATGACCAATTTTTATATGCCAAAAACTTCTTAAACACTGTAATTCATCCTATCTAAA ATACCATTGATTACTAGATTCACTATTGTTTTATATATGATTAAAAAAAAACACTGCCAG TTAATTTAATATACTGTCAACTGTAACATGCATCCTGATATCAAAAATAGTGAAAAGTAA AAAATGCACATTAGAAATTGATGGGGAAAAAAAATCACTTCTATCTCGTTTACTATTGTT CTATTGTTTTCCCATCTCAGAATCTTAGTTCAACCTCTCCTTGACTCTTGATATTCCACT CCTAGATCTCCCACCTTAGTGCTTTCTCCAGTGCCTATTTATATTCATAAATATCTTTAC CTACATAAACCACAACAGAATGAACTCTATTTATTAGGAAAAATAATCCTAAAAATAGAT GCAAAATAATAAGAAAAGAAAGGAGAAGTGGAAAGAGACTATGGAACAGAGAGAAGGGAC AAAAAAATGGTTCCAGGCAAAATAGCCTAAGCAACATGCATTATTACAAAGTTGGTTTTA AGTTTATGGTGTGGAATGGCTTATTATCAGGATGAACATTCAAGTCTTCCCAACAACTGC TCTCACTGCTTTGAGAAGATATGAGTCTGGCCTGACATGACCAACAAGTATTTTTAAAGC ACTTCAGACTTTACTGCAGCATTATCAAGACAAATAAATATGTTTTCTGTCTTTTCAAAA AATCACCTTTCATTCAACAATACTTTTGCGCTATCCCAACTTTTATGAATACTCTTAAGG TACTTGGAAATGATTTTACTTACTCTCCATCCACTTCTGGTCTTCTACATACACAATGAA ACTTTCCACCAAAATCTATGTACAGATCATTCTCCACAATATGAAAGATCCGTCCAATGA CCAGTTTATCCTTTGCAGGTCCCATCTGTGTAAGAGGAGAATGTCTCAGCATAGATGCAA AGGATTCCACATTTTTTGGAGAACCCTAAATATGAAAAGAGATATTTATATACATATAAC TCAACATGAAGGTATAATAAAGTCTTAAAGAAATTTTCTTAAAGTCAATTGTTGTAGCAA TAATTTTAAAATATATGTGGAATTTTGCTTTAAAATGCCAGTTATGCTCTTCAACTTCCT CTTCCATCCTTTCCTTCCTGAAGAGGAGCTAAAGAAAGTAGGCATCAAGGTGGAGCACAG TGGCTCACGCCTGTTATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAAGTC GGGAGTTCTAAGCCTGACCAACATAGAGAAACCCTGTCTCTACTAAAAATACAAAATTAG GGGTTCCAAGATGGCCGAATAGGAACAGCTCCAGTCTACAGCTCCCAGCGTGAGTGACCC AGAAGACAGGTGATTTCTGCATTTCCAACTGAGGTACCGGGTTCATTTCACTGGTGCTTG TCGGACAGCGGGTGCAGGGCAGTGGGTGCAGCCCACCGAGTGTGAGCCGAAGCAGTGCCT CACCCAGAAAACGCAAGGGGTCAGGGAATTCCCTTTCCTAGCCAAGGGAAGCTGTGACAG ACGGCACCTGGAAAATCGGGTCACTCCCACCTTAATAGTGCGCTTTTCCAATGGTCTTAG CCAACGGCACACCAGGAGACTATATCCCATGCCTGGCTTGGAGGGTCCCATGCCCACGGA GCCTCGCTCATTGCTAGCACAGCAGTCTGAGATCAAACTGCAAGGCAGCAACGAGGCTGG GGGACGGGCGCCCACCATTGCCAAGGCTTGAGTAGGTAAACAAAGCAGTCAGGAAGCTCC AACTGGGTGGAGCCCACCAAAGCTCAAGGAGGCCTGCCTGCCTCTGTAGACTCCACCTCT GGGGGCAGGGCATAGCCGAACAAAAGGCAGGAAAAACCTCTGTAGACGTAAATGTCCCTG TCTGACAGCTTTGAAGAGAGTAGTGGTTCTCCCAGCACTGAGTTTGAGATCTGAGAACAG ACAGACTGCCTCCTCAAGTGGGTCCCTGACCCCTGAGTAGCCTAACTGGGAGGCACCCCC AAGTAGGGGCAGACTGACACCTCACACAGCCGGGTACCCCTCTGAGACGAAGCTTCCAGA GGAACAATCAGGCAGCAACATTTGCTGTTCATCAGTATTCGCTGTTCCGCAGCCTCTGCT GCTGATACCCAGGCAAACAGGGTCTGGAGTGGATCTCCAGCAAACTCCAACAGACCTGCA GCTGAGGGTCCTGACTGTTAGAAAGAAAACTAACAAACAGAAAGGACATCCACACCAAAA CCCCATCTGTACGTCACCATCATCAAAGACCAAAGGTAGATAAAACAACAAAGATGGGGA AAAAATAGAGCAGAAAAGCTGAAAATTCTAAAAATCAGAGTGCCTCTCCCCCTCCAAAGG AATGCAGCTCCTTGCCAGCAATGGAACAAAGCTGGACAGAGAATGACTTTGATGACTTGA GAGAAGAAGGCTTCAGACGATCAAACTTCTCTAAGCTAAAGAAGGAAGTCAGAACCCATC GCAAAGAAGCTAAAAACCTTGAAAAAAGATTAGACAAATGGTTAACTAGAATAACCAATG CAGAGAAGTCCTTAAATGACCTGATGGAGCTGAAAACCACGGCACAAGAACTACGTGACG AATGCACAAGCTTCAGTAGCTGATTCGATCAACCGGAAGAAAGGGTATCAGTGATTGAAG ATCAAATTAATGAAAGGAAGTGAGAAGAGAAGTTTAGAGGAAGAAAAGTAAAAAGAAATG AACAAAGCCTCCAAGAAATATGGGACTATGTGAAAAGACCAAATCTACGTCTGATTGGTG TACCCAAAAGTGACGGGGAGAATGGAACCAAGTTGGAAAGCACTCTTCAGGATATTATCC AGGAGAACATCCCCAATCTAGCAAGGCAGGCCAACATTCAAATTCAGGAAATACAGAGAA CGCCACAAAGATACTCCTCGAGAAGAGCAACTCCAAGACACACAATTATCAGATTCACCA AAGTTGAAATGAAGGAAAAAATGTTAAGGGCAGCCAGAGAGAAAGGTCAGGTTACCCACA AAGGGAAGGCCATCAGACTAACAGCGGATCTCTCGGCAGAAACTCTACAAGCCAGAAGAG AGTGGGGGCCAATATTCAACATTCTTAAAGAAAAGAATTTTCAACACAGAATTTCATATC CAGCCAAACTAAGCTTCATAAGTGAAGGAGAAATAAAATCCTTTACAGACAAGCAAATGC TGAGAGATTTTGTCACCACCAGGCCTGCCCTAAAAGAGCTCCTGAAGGAAGCACTAAACA TGGAAAGGAACAACCGGTACCAGACACTGCAAAAACATGCCAAACTGTGGACCATCGATG CTAGGAAGAAACTGCATAAACTAATGAGCAAAACAACCAGCTAACATCATAATGACAGGA TCAAATTCACACATAACAATACTAACCTTAAATGTAAATGGGCTACATGCTCCAATTAAA AGACACAGACTGGCAAATTGGATAAAGAGTCAAGACCCATCAGTGTGCTGTATTTAGGAG ACCCATCTCACGTGCAGAGACACACATAGGCTCAAAATAAAGGGATGGAGGAAGATCTAC CAAGCAAATGGAAAACAAAAAAAGGCAGCGGTTGCAATCCTAGTCTCTGATAAAACAGAC TTTAAACCAACAAAGATCAAAAGAGACAAAGAAGGCCACTACTTAATGGTAAAGGGATCA ATTCAACAAGAAGAGCTAACTATCCTAAATATATATGCACCCAATACAGGAGCACCCAGA TTCATAAAGCAAGTCCTTAGAGACCTACAAAGAGACTTAGACTCCCACATAATAATAATG GGAGACTTTAACACCCCACTGTCAACATTAGACAGATCAATAAGACAGAAAGTTAACAAG GATATCCAGGAATTGAACTCAGCTCCACACCAAGTGGATCTAACAGACATCTACAGAACT CCCCAACCAAAATCAACAGAATATTCATTCTTCTCAGCACCACATCACACTTATTCCAAA ATTGACCACGTAGTTGGAAGTAAAGCACTCCTCAGCAAATGTAAAAAAGAAATGATAACA AACTGTCTCAGACCACAGTGCAATCAAACTAGAACTCAGGATTAAGAAACTCACTCAAAA CCGCTCAACTACATGGAAACTGAACAACCTGCTCCTGAATGACTACTGGGTACATAACAA AATGAACGCAGAAATAACTAAGATCAGAGCAGAACTGAAGGAGACAGAGACACAAAAAAA CCTTCAAATAATCAATGAATCCAGGAGCTGGTTTTTTGAAAGGATCAACAAAATTGATAG ACCGCTAGCAAGGCTAATAAAGAAGAAAAGAGAGAAGAATCACATAGACGCAATAAAAAA TGATAAAGGGGATATCACCACCGATCCCACAGAAATACAAACTAACATCAGAGAATACTA TAAACACCTCTACGCAAATAAACTAGAAAATCTAGAAGAAATGGATAAATTCCTCGACAC ATACACCCTCCCAAGACTAAACCAGGAAGAAGTTGAATCCCTGAATAGACCAATAACAGG CTCTGAAATTGAGGCAATAATTAATAGCCTACCAACCAAAAAAAGTCCAGGACCAGACGG ATTCACAGCTGAATTCTACCAGAGGTACAAGGAGGAGCTGGTACCATTCCTTCTGAAACT ATTTCAATCAATAGAAAAAGAGGGAACCCTCCCTAACTCATTTTATGAGGCCAGTATCAT CCTGATACCAAAGCCTGGCAGAGACACAACCAAAAAAGAGAATTTTAGACCAATATCCTT GATGAACATCGATGCAAAAATCCTCAATAAAATACTGGCAAACCGAATCCAGCAGCACAT CAAAAAGCTTATCCACCATGATCAAGTAGGCTTCATTCCTGGGATGCAAGGCTGGTTCAA CATATGCAAATCAATAAATGTAATCCAGCACATAAACAGAACCAAAGACAAAAACCACTT GATTATCTCAATAGATGCAGAAAAGGCCTTTGACAAAATTCAACAACCCTTCATGCTAAA AACTCTCAAGCAATTAGGTATTGATGGCACGTATCTCAAAATAATAAGAGCTATCTATGA AAAACCCACAGCCGATATCATACTGAATGGGCAAAAACTGGAAGCATTCCCTTTAAAAAC TGGTGCAAGAAAGGGATGCCCTCTCTCACCACTCTTATTCAACACAGTGTTGGAAGTTCT AGCCAGGAAAATCAGGCAGGAGAAAGAAATAAAGGGTATTCAATTAGGAAAAGAGGAAGT CAAACTGTCCCTGTTTGCAGATGACATGATTGTATATTTAGAAAACCCCATCATCTCAGC CCAAAATCTCCTTAAGCTGATAAGAAACTTCAGCAAAGTCTCAGGATACAAAATCAATGT GCAAAAATCACAAGCATTCTTATACACCAATAACAGACAAACAGAGAGCCAAATCATGAG TGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTAGGAATCCAACTTACAAG GGACGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTCAACGAAATAAAAGAGGA TACAAACAAATGGAAGAACATTCCATGCTCATGAATAGGAAGAATCAATATCATGAAAAT GGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATCAAGCTACCAATGAC TTTCTTCACAGAATTGGAAAAAACTACTTTCAAGTTCATATGGAACCAAAAAAGAGCCCG CATTGCCAAGTCAATCCTAAGCCAAAAGAACAAAGCTAGAGGCATCAAGCTACCTGACTT CAAACTACGCTACAAGGCTACAGTAACCAAAATAGCATGATACTGGTACCAAAACAGAGA TATACACCAATGGAACAGAATGGAGCCCTCAGAAATAAAGCCGTGTATCTACAACTATCT GATCTTTGACAAACCTGACAAAAACAAGAAATGGGGAAAGGATTCCCTATTTAATAAATG GTGCTGGGAAAACTGGCTAGCCATATGTAGAAAGCTGAAAGTGGATCCCTTTCTTACACC TTATACAAAAATTAATTCAAGATGGATTAAAGACTTAAATGTTAGACCTAAAACCATAAA AACCCTAGAAGAAAACCTAGGCAATACCATACAGGACAAAGGCATGGGCAAGGACTTCAT GTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAATGGGATCTAATTAA ACTAAAGAGCTTCTGCACAGCCAAAGAAACTACCATCGGAGTGAACAGGCAACCTACAGA ATGGGAGAACATTTCTGCAATCTACCCATCTGACAAAGAGCTAATATCCAGAATCTACAA AGAACTCAAACAAATTTACAAGAAAAAATCAAACAACCCCATCAAAAAGTGGGTGAAGGA TATGAACAGACACTTCTCAAAAGAAGACATTTATGCAACCAAAAGACACATGAAAAAATG TTCACCATCACTGGCCATCAGAGAAATGCAAATCAAAACCACAATGGGATAACCATCTCA CACCAGTTAGAATGGTGATCATTAAAAAGTCAGGAAACAACAGGTACTGGAGAGGATGTG GAGAAATAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAGTTCAACCATTGTGGA AGACAGTGTGGCAATTCCTCAAGGATCTAGAACTAGAAATACCATTTGACCCAGCCATCC CATTACTGGGTATATACCCAAAGGATTATAAATCATGCTGCTATAAACACACATGCACAC ATATGTTTACTGTGGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAT CAGTGATAGACTGGATTAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCA TAAAAAAGGATGAGTTCATGTCCTTTGTAGGGACACGGATGAAGCTGGAAACCATCATTC TCAGCAAACTATTGCAAGGACAAAAAAACCAAACACCTCATGTTCTTACTCATAGGTGGG AATTGAACAGCGAAAACACCTGGACACAGGAAAGGGAACATCACACAGCAGGGCTTGCTG TGGGGTGGGGGCAGAGGGGAGGGATAGCATTAGGAGAAATGCCTAATGTAAATGACGAGT TAATGGGTGCAGCACACCAACATGGCACATGTATACATATGTAACAAACCTGCACATTGT GCACATGTACCCTAGAATCTAAAGTATAATAAAAAATAAATAAATAAATAAATAAAAATA AAAATACAAAATTAGCCAGGCATCATGGTGCATGCCTATAATCCCAGCTACTCATGAGGC CGAGGAAGGAGAATCACTTGAACTCAGGAGGCAGAGGTTACGGTGAGCCGAGATCACGCC ATTTCACTCCAGCCTGGGCAACAAGAGCCAAACTGTCTCAAAAAAGAAAAAAAAAAGAAA GAAATTAGGCATCTATACTTGGTGGAGGATGACAGAGATGTGATAGTCCAGGGTGAGGTC TCGAGAGCCCAGGCAGGGTAGGGAGAGTAGAAGAGTGCCTGTATATCAAGTCTCTGAGAA TGGGGTGGGGGGTGGTTAGTGGTCAGAGTATGAGCACGTGAGGAGGGCATCCAAGAAGCA ATTGACTTTATTCCTAGCACTGACCATCTGTAAAAAAATGCCTTCTAAATCAAGTTTAGT GAAAGTCACTATTCTTTTAATACAAATGTAAATATACATTAAGATAAAAACAATTAAGAG CCTTTCATCACAATGATCAGTCTGAACATGAGTTCCTGATACATAATTCTTTTTAAACAA CTTGAATTTGTTATACTTTTCTTTCTCCTAAAGTAAATTCCAAAAGAAAAACAGCTTGTT TTGTGCTATTCACTTTCCGGGAATCTTTTTACATATTGAATTCACTTGAGGTATGACTAA TTATTCTTTTTTTCTTACAAAAATTTTTTCCAAACACATTTTTTCCAAATCCGTGAACAC AGATTTGTGCCTTCTACTCATTTTTGTGTATGGAGTGGTGTGTGCAATTTGGTACAAACT AAAGGAAGTGCTAAGTTTCTATCTGTGAGAGCAAATCATGGAAGGACATTAACAATTTGA TCTGACGACCTAAATGCTGTATTTGGAATGAGTTTTACATTTGTTATTCGGGGAGAACTA CTAAAAGTTCAATAGTAAAGCACATTTACTTTTAAAGCTACACAACTATATTTGTGACTT AAGTTTAATGCATGTACTACTTGAAAGATTATAAACTCAAATGCCAGGCCAGGTGAGGGC TTGATAATCAGGATATGTGCCCAAGTTTAAAAGGTGTAGACACTACTCAGCTCCAGCTGC AGCTGCAATTCAAGTCCCCATGTTTTAATTTTTAATGTTTTAATTTTCCAAGAAAAGCCA GAAATCCACATATTAATGTAAATTTTCCAATTTTTAAATACTTATATGCAGGGGGATAAA GTTTTCCATTTTACAAACCCGGCAAAACACATCCAGGTGTTGAATTTGGCCCACGAACCA CAAGTTTATGACCTCTGCTTCAGGAAAAAGAAAGTCACGACATTTGGCTTATGCCAAGTC CCTCAGGTGCTAGAGGGAGGGTATGATGATGAATTTACTTGGTGAACTGAAACACACAGG GAAAAAATCCTTAGCACAAAAGGGTCAATCTAAACTAAAGACAAGTCAGTAGGCCTAGAG GCCAACTAGAGCTGAAAAGGTAACCAGGAATGTATGCCATGAGCAATCATACTAGTTTTA TAAATCCACAAAATACAACATTAAAGGTCCTTAAACAAGCACTTTGAAAATAGTTCTTTC TTGCAGAGCCAGAGATAAAACAAATCCTACAGAGGTAACACAGACACAGCTGACTTGCCC TTTAGAGGTAGTGTAAAAGAGTAATTCTAAGTAAGCCATTCTTTTTTTTTTATTTTTTTA TTTTTATTTTTTTTTGTAAGCCATTCTTGACAAGAGCAGCTACATAATCCTTTGCTGGGA GCCATTATTCCATCCATAGTAGCTGCCACTAAAGCAGATGAGAATAGCAGTGCTCAAGAG AAGAGCAAACAGTATCAACTTGGGGGTCTCTGCTTGTAACCAGGGCAGGTCCTGCCCACT TTCCCTATGATCTGCTTTCCCATTACTCCACTTTTATGGTTGATATCTACCAGAGTTCCT CTGTTCTTTTTCTTCTTTTTTCGCTTTGGCTATTTTTTTTTTTCAATTGGCTGACTTTCA ATTGAAGCCATAGTCCAATTAAAACTAAATGACAGGGGCTAGGCATTGTGGCTCACGCCT GTGATCCCAGCACTATGGGAGGCCAAGGTGGGTGGATCACTTGAAGTCAGCAGTTCAAGA CCAGCCTGGCCAACACGGTGAAACCCTGTCTCTACTAAAATACAAAAATTAGTCGGGCAT GGTGGCATGTGCCTGTAATCCCAGCTACTCAGGAAGCTGAGGCAGGAGAATCACTTGAAC CCAGGAGGCGGAGGTTGCAGTGAGCCGAGATGGCACAACTGCACTCTAGCCTGGGCGACA GAGTGAGACTCTCAAAAAAAAACAACAAAAAACAAAAACAAAAAACAAAACAAAACAAAA AACCAGATGACACTAAGATACAGTAGTAGCAGATCCAGTAGTTAAACTTTTACTGGAGAT AATTCAGCCATCACTAGGACCTGTTCCTAAAATAACACAATGTCCTTTTTCAATTGTGAA GAGATGTTTGAGCTAAGATTAGTATAATAGTAAGTGGTATTTTCCCCTTGGTTTTAGAAA ATTATTGAGTGCTCTCAACTGTTTAAAAAGATTCTCTTGAGATTTTTAGTAAGTCTGCAG TTAAATATTTATTACATTATAAACTTTATAAAGTTATAGTTACTTTTTATAGGTAACTTT AAAATCAAGTGGAAGTAGAACATTTCTCCTCCATTTTTTGCCTCTATTATATTTTGCAAG GAAGTCAGTGTGTTTTTGGCGAGTGAAATAATTTTACCACAAGCATAAGAACCCTGGATT AACACCTGAATTTGCTTTTAAATTGTAGCTTATTATTTCATTTGATTTTTGATATTGCAT CATTGATTTTGGGAAGCTACATCAAACAATCAGACAAACCCTTGCTTCAAAAATCATAGT CTAGAACCATCTCTGAATCCTAGGGCTTATGCCAAAATGTACTCATTTACTTGTCAAATG ACTCCTAAAAACAGTAAATGTAGCAACTCCCACAATCCATGTTCACTACAGGGAGTCCTG TTTATAAAGTCTCTAAACTAACATTGATAGCTCCTCTCATGCTGATATAGACTGCAGAGA CTGGAAGCATACTGTCACCGCTGGATATGTATCATAGAGCTCAGTGCCTAACCCTGGAAA ATGTTACAATAAAGCTCACTAACTGAGCTGTCACAGGTACTAACTTGGAGTTGACTATTT CCTTTAACAGTTGGTCATAGAGATCAGATCTCCTGCTATTCTGCTGTACTATTTTCTCCT TTGAAGCCTGAAAGTTGACAGGACCGTCAAGGTAGAAAGGAGTAAGGTAAAGGAATTACA GACATATGGAACAGTATCACTTTCATTTATTCAATCATGCATTCATTCATTCATCAAACA TGTGTTGTCTTTTTAATATATATTAAGCATATATATACCTATCATGCATATGAGGACCAT TTAATATACAGCTTGGAAACAGGGGCAACTAGTGCTAAAAGAATATGAGACATCAACTAA TCCAACTACCTCAAGTTTTACATGAGTACCATACATGCTATTCAAAGTTACATGGGATAC TGAACAGTGGTTCTTAAATAAAACTTGCTGCAGAAGATAGAAAATAGATAAAAACATCAT AGCAAACTTAAAAGAAAACAGTACAGAAGAATAACAAATACGAAACCTGACTTCTATGAC CAACTCAGCCAATAAACAGCGAAAAAAAAACCCTGAATAAGTCATTTAACTTCTCTAGAT CTGTTTTCTCATTTGTAAATTAAAGGATTGGATAACTATAAATTTTCTTCCAATTCTATA AGGTAGTAGGAATTCTTAAATATTCTAAAATATAAAAAGGATTTTATAAAACAATACAAA TTAGAAATGGGAGACAACATCCTACCCAGTTACCTCTTTTAATGTAGACAATAAAAACAG CTGGGTGCAGTGGCTCACCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTAGGTGGATCA CCTGAGGTCCGGAATTCGAGAACAGCCTGACCAACATGGGGAAACCCTGTCTCTACTAAA AATACAAAATTAGCCGGGTGAGGTGGTGCATGCCTGTAATCCTAGCTACTCAGGAGGCTG AGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTACGGTGAGCTGAGACTGCGCCAT TGCACTCCAGCCTGGGCAAAAAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAGA AAAGAAAAAAGAAAAAAAACAATAACAATAAAAGTAATGAAATGGTATATATACTTTAAC TACTTCATACTGGTTAGCAAGAAAAAAATTTCAACATGCATCTCCAAAAATGACCCACTT CTATTAACCGTGCTATAATAACTTTTGTTTCTTTAACACTAACCAATAAATGTTACGCTC GCAACAGAGTTCTTTTATTGAAATAAACGTATTGGTGGCTCAAGGTGATAAGGTACTTAC ATTTATCTCTCTCCCTCCTGAAATCCCATTAAATGATGGTAAAATAATAAATTAAAAAAT TGTAAAAATTATAAACTCTCAATATTGAAGAGAACAGATGGAGAACAAAAGTATACAAAC ATACTTTCTAGTGGACAGAAAGCATGTGGAAGAGTGATAATTAATGAAGCAGAGTGAAAT TCAAGAAGAAGAAGCTGTGAAAAAAAGAAAGCTATTCTATCCTGAAGTATTCCATAAAGG TATGGAGCTCAGTCATGCCAGGCTGCAGTGAGAAGACAAGCTGAAAACAAGGAGAATAGC TAAAAACAACAGAGGCAGGGCAGTCAATATTCTGTCAAGCACAAAATTCCTCAAGTGCAT AATATCTGGTAATAGGCATGTATTATCCTGTCAAAAATAAATATATTTTTTCTCTTCCCT TAAAAAAATCAAACAAATTGTACAGAGGAGAGCCAAGTTTGGGATGGTTTGTTATGCAGC AGTAACTTATACTGTTTCTATAACCTATAGAAGCAGCAAAGAAAAGACTCCAAATGACAG CTGTGCAGCAAGCATATGAACAATTTGTGATGATTCAAATACGAGGGCTCCCAAAGGAAG GCTGGGAAGTCTGGCCACATGGCTTGAACCTTGGCTCTACCGCTTACCAGCTCTGGGGAC AGGTCTGTGCACTTAGAATCTCTGTGCTGCTGTTTACTCATCTTATAAAATGGTGTTTGT AATTATATCTATCTATTTTACAAGATTGTTGTAAGGAATAAATGTGTGGCCATATGTAAA GCACTCAAATAGTGTCTGAAGGTAAACAGACCCTGTCAAAAACTTTAGCTTCTTTAAAAA TTAATTTCTTATAGACTCAGTCACCACCATCAAGTTTTATTGACTAATCTAGTATTTGTC AACCAAGATGATTTCCCCCCTGCCACCCCCACTCCAGGGGACATTTGGCAATGTCTGGAG ATGTGTTTGATTGTCATGACTGAAAAATCAACAACTCTTCTTAGATGCATCTGAGAGGTG GGGGTCACAGGGAAAACTGCTGTTCTCAAATGTGGAGAGACAAGTGAATGCAGAGAACTA CTGAAAAGAAGCCTCCAAGAAGAAACCTCTGTGGGAACCAGTGCCGAGGTAGGGAAACCC GAGCTGTAACTGGTGAATTGGTGGATGCTCAGTGGGACAAGTCTGAAAGTTAAAAACTCC AGAGAGACTCAGTTATTGGGGACTCTCACACTTTTGTGAGTTTTAACTCCAGGAGCTCAA CCTGGTCCTTACAGTGAATATAGGAGAAAAATCCCCTTGTACTTCAGACGGCAAGTTCTG TGGGGAATAGAACTATTTTGAAATACATCAGAGCACTCTCTCTTATTCAACAATTCATTT ATCAAACAGGTGTTGTCTTTTTAATATACATTAAGCACATATATAAAACTATCATGCATA TGACATGTGTCCTCAAGGAAACTCTTCAACCAAAGCCTAAACACTTGTCAGAGCCTAAGT GTCCTGGAGGAAGGGAAATAACCAATTCTAGCTGGCACTAGTCATTCTGTCCTACCAAAA GAGAGGGAAACACTGAGAAGCAAATGTGCAGTTCATAGTCCAGAGGCACAGGCTCACTAG AAGACTGAGACCCACTCATAAGACTATAGAACACTTTCCCTCCCCACACACCCTATCACC ACATTACTAAAGGCCGATTGACAGCCATTCCTTTTACCCAATACATCATGCCCAGCTATC AAAAAGAAATTACAAGATAGACAAAAAAGCAAAAAACACAGTTTGAAGAGACAGAGCAAG GATCAGAACCAGATTCAGACACAGCAAGGATACTGAAATTATCAGTCCAGGCATCTAATA CAACTATGATTAAGACACTAAGGGCTCTAACGGAAGAAATAAGATGTAAGAACAGATAAG CAATGTACGCAGAAAGATGGAAATTTTAAATAAGAATCAAAAAGAAATGCTAGAGATCGA AAGCCCTGTAACAGAAATGAAGAATGCCTTTGATGGGCTTACAGGTAGATGACACAGCTG AGGAAAAAAAAAAACTGTGACTCTGAAGATACCTCAATAAAAACTGCCAAAACTGAAAAG CAAAGAGAAAAAAGATTGAGGGAAAAATTGAACAGAATATTCAAGAACTTTGGGACAACT ACAAAAGGTGTAAACTAATGGGAATTCTAGAAGGAGAAGAAAGACAAATACAGCAGAAAT ATTTGAAACAATAATGACTAAGACTTTCCTTCAAATTAATATCAGACACCAAACCACAGA TCCAGGAAGCTCAGAGGACATCAACCAGAATAAACACCAAAAACACTACATCTAGGCATA TAGTATCATTTTCAAACTACAGAAAAATCAAAGATGAAGAAAAAATTCTAAAAGAAGCTT GGGGGGAAAACAGCTTTCCTACAGAGGAGAAAAGATAAAAATTATATCCAGCTTCTCCTC ATAAATCATGCAATCAAGAAAACAGTGGAGTGAGATATCTAAAGTGTTAAGAGGAAACAA AAAAAAAAAATACTAACCTAGAATTCTGTACCCTGACAAGTTATCCTTCAAAAATGAAGG AGAATTAAAGACTTTCTCAGACAAATAAAAATTGAGGGAATTTGTTGCAAGTAGACCTGC CTTGCAAGAAATGTTTAAAGAAATTCTTTAGAAAGAAGAAAATTATAAAAGTCAAAAACT CAGATCTACATTACATAAAGAAAGGCAGAACACAGAGAAGGAATATGTGAAGGTAAAATT AAAACTTTTAAGTTTTTAATTAGTAATTGATCTAACAATTAACAGTTTGTTCATGTTAAA CAATTTGCTAATAATAAAAGGGTTAATTATCTGAAGAAGTCGGAATAATCCTTAATGTGT ACATGCCTAAAAATAGTCAAAAACCATGAGGCAAAAACTGACAAAACTGCAAGGAAAAAT AGATGAATCATTACAGTTGGAGACTTTAATGTCCCTCTATCAGAAAAGGACAGATCCAGC AGGGAGAAAATCACTCAGGATATAGCTGAACTCAACAACATCATAAATCAACTGGATATG ATGGACATCTGTAGACAATTTCATCCAGCAACAGCAGAATATATATTCTTCTCATGCCAC ATGAAACAGTCACCAAAACAGACCACATTCTGGACCATAAAACACACCTTAACAAATTTA AAGGAATAGAAATCATGCAATGTCTGCTTTCAGACCACACTAGAATTTAACTAGAAATCA GGAATAGAAAGATAGCTCAAAAATCCCAAAATTCTTAGAGTAAACAAATACACGTCTAAA TAACATGAGTCAAACAAATCTCAAGAGAAATTTAAAAATACTTTGAACTAAATGAAAATG AAAACACAACTTATCTAAAATAAAAATTAGCACAGAAAGCAATGAAACTGAAAACAGGAA ATCAATAGAATCAACGAAAGCAAAAGTTGGTTATTTGAGGTAAGCTTCTAGCCAGACTAA GAAAAACAAAAAGAGAGGACACAAATTACTAATAATAGAAATGAAAGAGAGGACATCACT ACATATCCCATGAACATTAAAGAAATACTATAAACAACTCTATACCCACAGATTTGATAA CCTAAATTAAATGGATTAATTCCTTGAAAGACAAAGTCTGCCAAAATTCAAGTAAGAAGA ACAGATAATCTGAATAGGCCTATGTCTATTAAAGACATTAAATCAGTAATTAATATACTT CCAAAACAGAAAGCCCCAGGTCCATATGGGTTCACTGGTGAGTTCTACCAAACATTTAAA GAAGAAATCAAACCAATTCTCTACAATCTCTTTCAGAAGATAGGAGTGGAACTTATCCTA TGAGGACAGTAATATCTTAATATCAAAACCACACAAAGACATTACAAGAAAAGAAAACTA CAGACCAATATTTCTCATGCATGTAGATGCAAAAATCCTCAACAGAATATTAGCAAATCA AATCCAACAACATATAAAAATTATATACCACAACTGAGACTTACGACAGGTTTAACATTC AAAAATCAAAATGTAGACAAAGCATTAATAACCAGGATATATAAGGAGTTCAAACAACTC TATAGGAAAAAAATTCTAATAATCCAACTTTAAAATAGGCAAATAATCTCACGCCTATAA TCCCTGCACTTTGGGAGGCCGAGGCGGGCGGATCACAAGGTCAGGATATCAAGACTATCC TGGTTAACATGGTGAAACCCCATCTCTACTAACAATACAAAAACAAAACTAGCAGGGCAT GGTGGCAGGCGCCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCGGGAGAATGGCATGAAC CCGGAAGGAGGCAGAGCTCGCAGTGAGCCGAGATCGTGCCACTGCAATCCAGCCTGGGAG ACAGAGCAATACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAGGCAAATAATCTGAATGG ACCTTTCTCGAAAGAAGACATACAAATGGCAAACAGGCTTATGAAAAAGTGCTCAACATC ATTATCATCAGAGAAATGCAAATCAAACCTACAATGAGATATCATCTCACCCCAGTTAAA ATGGCTTTTATCCAAAAGACCAGCAGTAATACATGCTGATGAGGATGTGGAGAAAAGGGA ACCATCATATACTGTTAGCGGGAACATAAATTAGTACAACCACTCTGAAAAACAGTTTGA AGTTCCACAAAAAACAAATAACCAAAACTAAAAATAGAGCCACCATATGATCCAGCAATC CCACTGCTGGTTTTATACCCCAAAGAAAGGAAATCAGTATACTGAAGAGACATTTCCCAT GTTTGCTGTAGCTCTGTTCACAATAGCCAAAATTTGAAAGCAACCTAAGTGCCCATCAAC AGATGAATGGATAAAGAAAATGTGGTACATATACACAATGCAGTACTACTATTCAGTCAT AAAAAAGAATGAGATCCTGTCACTTGCAACAACATGGATAGAACCAGAGGTCATTACGTT ACGTGAAATAAGCCAGGCACAGAAAGACAAACTTTACATGTTATTATCTGTGGGAGTTAA AAATTTAAACAATTGAACTCATGGAGACAGAGTAGAAGGATGGTTACCCAGACGCTGGGA AGGGTATTGGGGGTTTGTACCTATTAACCATCCCCACTCCCCTATATGTGATATAGTATA CTTATAGTATATAAGGGGGTGGGGATGGTTAATGGGTACAAAGAGTAGTTAGAAAGAATG AGTAAGACCTAGTGTTTGAGAGCACAACAGGGTGATAAGCAATAATTATTTAACTGTATA TTTAAAAATAACTAAAAGAGTTTAATTTGATTGTTAACACAAAGAGTAAATGCTTGAAGG AATGGATACTCTATTTACTATGATGTGATTATTACATGTTATATGCCTGTATCAAAGTAT CTCGTGTGCCCCCTAAGCATATACACCTACTATGTACCCACAAAAATTAAAAATAGAAAA AAAATGTAATCCATCACATCAATTGGCTAAAGAAGAAAAATCACATGGTCGTATTTCATT TCGTCAAATGGAAAAGCATTTGACAAAACCCAATACCCATTCATAATAGTAACTCTCAGA AAACTAGAGAAAGCTTCAACTTCCTAAAGAATATCTACAAAAAACCTACATATGTAATGG TAAGTAACTTGAAACTTTTCCTACTAAGCACAGGAAGAAGGCAAGGATGTCCCCTCTCAT CACTGCTTTTCAACATTGTACTAGAAGTCCTAGCTAATGCAATAAGACAAAAAGAAAAAA TAAAAGTATACAGATTGGGAAGGAAGAAATAAAACTGTGTATGATCATGGATGGCATGAT GACCTATGTAGAAAATCAAAAAGAATCAACAAGAAAAAAACCTCCTGGAATAAGTAATTA CAGCAACATTACACAATATAAGGTTAATATACAAAAAACTATGTGGCCAAAGTATTGGTA GTCATTAATGTGTAAACCAAGAGTATGAGACAGGTCTAAATCAATTTGGAAAGTTTATTT TGCCAAGGTTAAGGACACGCCCATGACACAGCCTAAGGAGGTCCTGAGACACGTGCCCAA GGAAGTCAGGGTACAGCTTGGTTTTATACAATTTAGGGAGACATGAGACATCAATCAATA CGTGTAAGATGTACATTGGTTACACTGGTTCAGTCCAGAAAGGCAGGAGAACTAGAAGCA GGTTGCGAGGGTGGCTTCCAGGTCATAGGTAGATTTAAAGATTTTCTGATTGGCAATTGG TTGAAAGGGTTATTATCAATAGAAAGGAATGTCTGCGTGACCATAAGGCATTGTGGAGAG TATGGTTTTATCATGCAGATGAAGCGTCCAGGTAGCAGGCTTCAGAGAAAACAGATTGTA AATGTTTCTTACTAGACTTAAAGAGTCATTTCTATCACTAATTCTGAAAGGAGGGAGGTA TAATGAGGCACGTCTGGCTCCCCCTTCCCATCACGGCCTGCACTAGTTTTTCAGGTTAAC TTTGGAACGCCCTTGGCTGACAGGAGGGGTCCATTCAGATGGTTGAGGGGGCTTTAGAAT TTTATTTTTGGTTTACAAATGTAAATGCTGGTCAATGAAAATGGTAAGTATGAAGAAAAG AGAAAAGCTGTGAGCCAGATGCTGACGAAAAATGGAAAGAATTGAAAAGATTTTTATCAA GGAGCCTTTTTAAAGTATTTCTGATAGAACAGTAGTCTGAAATGGTACTGAGAAACGAGA ACGAAGATGAGTCATTTTTTCCTCCTAGCCTTGAGACCCGTTGCAATCTATACTAGGGAA GACCAGAAGGGAAGCAGTGTTATCAAGGGAAACCAAGAAAGCAAGCAAGAAATACTTGTA GAGAAGGTTAAAGGGGAGATTGTTCGTAAAAAGACATAGGAAATTTGTGGCCAACGAACA CACATTTACAGAGCAGGCCTGAAGGAAAAAGGTCAGGTTGTAACAAAGAATAGTGATCTC TATCATAACCCATAGGACAGAAGAAGAAAACACTGGAATTTCTATTTGTTTTTTTTAACT TCACCTTCAAAATGTTTTTATGTGTAAATGCTTTAAAATGTATATAACAAAAGAAACTAC AGTACGAATATATATATTCGCACACACACACTTTTTTTTTTTTTTTGAGACTGGGTCTCT TTCTGGCGCTAGGCTGGAGTGCAGTGGCACAATCTCGACTCACTGCAACCTCCGCCTCCC ATGTTCAAGCAATTCTCCCGCCTTAGCCTCCCGAGTAGCTGGGACTACAGGCATGAGCCA CCATGCCCGGCTAATTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTGGTCAGGA TGGTCTTGATCTCTTGACCTCATGTTCCGCCCACCTTGGTCTCCCAAAGCGCTGGGATTA CAGGTGTGAGCCACTGCGCCCAGCCACAAATGTATTTTTTAAGTAAATACTGGAACATCT GCTCAAAAATTTATTAATGAAGGGACATGATCAAAAAAGTTTAGAAATCTCTGTAATAGT GGTATATCGTGGGAGCAGGAGAAACATTATGCTAGATAGGGAAAAACAGTTACAAAAGGA GACTGGACAGTCAGTCTCTCTCTCATTTTATGAGCAGAGCTGTAAGCCAGATGCTGACAG ATGCATAGACTGGGACCAAGGGATGCTTTTAAGGTTTCTAGTAAGACAGAAGTTGTCTGA CTAAAGGCTAAGGTATGCAGGTAGGCATGTGGAACTTTACTTCTAACTATTCTTGGATTT TTCTGGTATTCTACACTGCATTGCTTCTAACAACAAAAAATTACCTTACAGGAAATAATG TGGGATAACTGTCACATGTTTATGGAATTCAATGGTCTTATCAGTGCTGGGCCCGAGAGA CCAGTGAAATGCTCCCTTTAAAAAAAATTAACTTTCTATTTAAAAATCATTGTAGATTCA CATGCAATTGTAACCAAGAATACATAGAGAGCCCCTGCACCCTTACCCAGGGCTCCCAAT GGTAACATTTTAGAAGACTATAGTATGATATCACAACTAGGAAATTGACATTGACACAAT CCACCAATATTCAGATTTCACCAGTTATACACGTAATCATCAATGCAATTTTATTACATG TAAAGGTTCTGTACTGGCCATCACAGTCAAAATGCAGAACAAGTCCATTACCACAAGGAT TCCTTGTGCTGTCCTTTTGTAACTCCACATATCCCTTTTACCTCCCTCCTTCCTAACTCC TAGTAAGCACTGACCTGTTCTCCATCTCTATAATTCTGCCATTTCAAAAATGTTGTATAA ATGAAATCACACCATATGTAACTTTTTGGGACTGGCTTTTTTTTTTTCACTCAGCATAAT TCCTTTGAGTCATTCAAATTATTTTGTGTATCAAACACTCATTACTTTTTACTGCTAAGT AGTATTCCACGGTAAGGATGTACCACAGTTTGTTTAACCATTCAACAGCTGAAGGACATC TAGGCTGCTTTCAGTTTTTGGCTATTACAAATGAAGCTGTTAGGAACATTTCATTTCTTT GGGATAAATACTGTGTGTCCCAGTGACACCCAGTTCTCAGTGTACATTTATGTCCCTTCA GAGAATCCAACCATCTCAATTTGGGTAGCTGGCCAGAGGCCAGGCAACTTGTTCAGCTGC CAACTCCTAGACTGAGTCCACCACTCATTTCCTGGCAGTTGTCAACAATGGAATCTCCAA AGCTTTAAAAAGGTAGGCAAAACCCAAACTGAATCAAGACTATTTAGTTTTATTCCCAAA TCCCAACAAACCAGGCTCCACTTGAATGTGCTTAATTGCTCTTATTTCCTGATATTTAAT GCCAATAGATAAAAAACTTAAGGGCCATAATCAGGTTATAAAAATTAAAGTGATTAAAAG AGAAAAATTTAAGTGTAGCCTTAGAAGCAAACTTAGACACATTAAAAGATGGAAGTGAAA TTTCTGAGTAAAAATGAGAGTTACGATCTCCAAATAGTGAAAAACCTAAGGTTGGCTTGG GAAGTCATGAGTCTGATTGGGTATAATCAGATCATATGACCACCCAAAAACAAAATACAT ACAGAACATATACATCTTTTCTTTTAAGAAATGTATAGTACTGCTTATAAGCATGTTACA GGTGTTAACAAAAACCTACTTTCCCCAGAGAATTCTATGTACTTCTTCACTATTTCATTG TTTATATATTAACTGGTCATTTCCTCTAAACATGCTTTGAAAATGTGAGACATACAACAT TTCAAAAGATTTTTATTACTCAGAGGTAATTCTCCTAGAATTCTATAATGTAAAAACAGG TTGGCACCATCGTTAAAACCAGAAACATTTTCCATCATTCCTTTACATATCAAATAGTTT TTAAAACACTGGTATAATTCTTAAAGTTGTCAGTAAAACTGATAAGAAAACAAAGGGTTA AGTAAAACTATATAATTTTACTATTACAGTATATGAATTTAGTGGACTTAAAAATTATAC TAAAAATAAATTAATTTCCCTATTATATTGAAATAAGCCCTTTAAATCTATATATTTTTA TTTTTCCAGTATTCTGAAAGGATTGAACATCTGATTTTAGATATTCTGTCTTCTGGAATA TTCGAATATTTTGAAATAAAAAATACTAATAAAAATATTCACAAAAAAGTAAAAAATTAC ATTTAAAAATATTTGCATGAAATCTAATATATTGCTAAAATAAGGTAAAACTATAAACTG TCATGTAACATCAGTATTTTAAATAAATTTAAAATTTGAGTAAAATTTTTACTGTGCAGC CCTAAAACTCTCTGAAAAACATTTTTTCCAATGTTCTGAAAAGTAGCATGCCACCCTCTA CTGCTAAGAGTCATAAAGCAGAAAAACCAATTCTTTGCTCAACTATTGCCACCTTGTGGC TACGAGATGAGTTATATGCCATAGCACAGCTCCCAATTGCCTTAACAGATTCTACAAATT TATATTGTCTAAGTGACATAAGAAGGATTAAGGTTTTAAAAATGGAGGGAAAATGGTACC TGACTTAAATGGTTATAAAAATGAATGGGACGGCCTGGTGTGGTGGCTCACACCTGTAAT CCCAGCATTTTGGGAGGCTAGGGCAGGCAAATTGCCTGAGCCCAGAAGTGCGAGAGCAGC CTGGGCAATATGGCAAAACCCCATCTCTACAAAAAAATACAAAAATCAGCCAGGCATGGT GACGCACAGCTATGGTCCCAGCTTCTCAGGAGGCTGAGGTGGGAGAATCACCTGAGCCAA GGGAGAGAGGTTGCAGTGAGCCAAGTTTGCACCACTGCACCCCAGCCTCAGCAACAGAGC AAGACCCTGTCTGGAAAAAAAAAAAAGATTTGGTTGCTACTCTAAAAACAAAACAAAACT AGTTGAAGGGAAAGATGCATAAACCAATATTAAAGCTAATGAAGCAAAGTAAAAGAAAAG TAGGTAAGTGAGCATGGGATGAGTATGGAACCTACAACCACCATACAGAACAATGGCATT ACACTTAATGCCATTTAACTTCGGTTCCCTTTAACTAGTAACCCGAGTGTGTAATAGGAT AAGAACTTCATGATGCATTGCTCTTGATTAAATTCCTGGCTGCAGGGGAAAGTTCTTTGT AAGGATAATGTGTATGGGCTTATTTCTGAGGTCCACATGTAAGTAAGTCTACACTTTAAT GACTATAAGAACTAAATCAATAGGTAAAACTTGGACTTTCACCATATACATATTTTTAAG TCTAATAATAGGCCATCTGAGATGCTATTTTTCATTTGTAATTATTCAACCATCAAACTG TTTAAATTTCATTCCAACTTAAATCAGCAAATATATACTCAATCCCTACTTAAGTGTAAA GCATTATGCAAAGGATGAAGAGGGTGGACTGAAAATGGCCCCTTGTTCTTCAGGAACTAC AGCTAGAAAACAGGATAAAACAGGTTTGTAAATGACTTTACTATGAGAGCTGTGGGTATA CCATAAAGGTAGTAAAACACAAAACTCCAGAGCATTCAAAAACAGTTTCATCTGTTTGGT GAGATCACAAAGGTCTAAGAGAGGAGGTGATTTTTACAACAGAATTTGCAGCAGGGAAGC TAATTCCAGGGTAAAAGGTAAAGAAATAATGATTTGTTTAGGGAACAGCAAAATTCATCT TCAAAAAGAATATTTTAAGCAGAAACCATTTTACAAATGAAATCTTACATACAATCCCAA TATATATAGTGTAAATGTAGTATTTTGTTATTTTAAGTGCATTTTATGAGTTCAAATTGA TAGCACTTACTATAAAGTCAAAAACTGTCAACATGCAGTTATGATAAAAATCAAAAACTG AAATCAGGAATGAAAGATGATAACCCCAGTTTCCAATTTCTATATTTTGCTTTAATTGTC GAATATCAAGAAAATCCACCTATTACACCCCATGAGTTGATACGGGGGTGAGGAAACATT GTCATGCACTGTAGGTGGGAGTTCAGTACAAACAGGCTGTAACTCAAATTGTGTGTACAC TTTTACCCAACATATAACCTACAAATACACTCTTGTAAGTACGCAAAAAATGCAAATGTT CACTGCAACACTGTGTTAGAAAACAAAAACAAACAGAAACAACCTAAAAGTTCAATAATT AAGGCCTTCCTACTTAAATAAATTATGCTACATCCACACCATGGAATACCAAGCAAATAT TATGTAATGATAAGGAAAAATAGTCATACTTAGGTAAAAACTGCAATTTTCAGCAGCAGC AACTAAAACATACTAAGTGCTTATTAAGTATCAGGCACTTGTGTTAAGTGTTTTAAATAA TGAATTCATTGAATCTCATAAAAATCTCATGACATAGGGGGAAAAGGAGATACACAGATA TTAAGTAATTTTCCAAGGCAACACAGCTAGTAAATGGTAGAGGAACCAGGATTTAAACCA AGATTGCATGACTGCAGAATTTACACTCTTTAACTGTAATATATTTTAAAACAGTATTCA TACTACGAACCAATTAATGTTTTTAAATATATATAGCAATACTTAGCTTATACTTACGTG TGTAATATAAAACTCTGCAGCTATGCATAAAAAACACACTCTCCAGCCTTGAGAAAGTAA GAAAAAGGGACTTTTACATTTCACATAATAACCTGCAGGGCTATGTAAATTTTCTTTCTA AAGTAACCAAATATTACTTTTGTAAAATTTGTAAACAATATTTTTTCAAAAACCCTGAAT ACACAATTGGCGTTTATTCATCTTGTAATCTCACGATACTGTTCAATTAAATAGGTCCAG TAAGTTCAAAAGAGGTAAAGCAAGTTTTTTCACAAGTTGAATTCCTATCAATACCCAACA ACTCCTCATATTCCTTACCATAAATATGTTAGAAAAACACTGAAAACTTCCAGTAAATAC TAAAACTAAAACTAATGTGGTATTTTCAATTTCTTACTACTCTTAAAATTATTTTTACTC AATTATTCTGGACAGGCACATTCAACTGACATGCTCAAGACTGTACTATTCTTGTACAAT TGTTTGTGGACAGTGACACATATATTACAATTCAACGACAGGCCAGGTATAACTGAAGTT CAAATATGCACTACATGTACTATTCATTCATTCACACATTTGACAAATATTTACCGAGTG CCCACTATGGGTCAAGGACTGTGCTAGGCACTGGAAATACAACAGAATAAGAAAGACAAG GTCTCTGACCTCCTGAAACATTTTCTACTGGGAAAAAAGTTAGTAAAAATTTTATTCTGA TGTGTCATGTGTTACTCTGGCACCACAAGTTAACATATTAGTGATGACGAATGTCCTTAC ATTTGGGATTAAAAAAAATGGCATGTGCATGGTTGTTTTCTGGTGTTTTTTGTTTGGTTT TGGGCTTTTTGCCATGAAAAACTTAATTTTATTGTCTCTTTGAATGACACAGCTCAACCT CTAGTTAGAGCATATACTGCCTTATGTTTTTAAATAGCATTTTATATTCATTCATTAAGA AAAAAAATTATTTTTTAGAGTACTTTTAGGTTTACAGCAAAATTGAGAGTACAGTACAGA CATATCCCATACCCCTCCTGTGCTGACACACACATAGCTTCCCCCACTGTCAACATCCCC CACCAGAGCGGTACATCAGTTACAAGAGATGAATCTACACGGTTTGATAAATTAAAGTTC ATTATTAAGAAAACAATGGGACTTCAAAGAACTGTGTAATTGTGGAAGCATCTCTGTGAA ACTATTCTCAGGAAGGCAGAAGGCTGGAGAAGAAACGGCTGGGGCCACATAAAAGCTAAA ATGCACTGAATAAAGCTTACTCTGTACCAGTCAATGTACTGAGAGCACGTTAAATGTATT ATTTCACATAAACTTCCCAGTAACTCCAGTTGAAGCATTATCTCCACTTTGAGATAAGAC AGCAAACTTAGATAGGCTAAGTAAGTTGCCCAAAGTCACTCAGTTGAAAGATGGCAGAAA CTGGAAACCTGAACTGAGCCGAAGCTTTTAACCCAAGCAGGGTCTTGAATGGCAGTAGGC CTCTGAAGCCACAGTAGAGAGATGCACCATTGTATATTTAATCTTGCAGGCAGTGTGAAT GGAGGTTTAGAAGATTCTCAAGGAGAGCAATAAGTAAATAACCTCATTAAGTCTGATTAT AGAGCCCAACTTTAGGAAGATAACTTGATCCACAGTGTGTGTAATGACCTGAACCAGGGA GCAACTGAAGTCAGTGGTATCAATTAAGAAGGAGTAAAGGGGTTCACGTAAACTTCAAAT GCTTCAAAGCTAAGAACTTGCTGAACGGAGACTACAACACAGCCTCCTGATATCCTCCTC CCCAGGGAATTTTATTTCCATTAAACCAAGATGTCAAAGACTTGTGAATAAGAAATTGGT GAACTGTACATCACAACCAAACACATTTACCCATCATCTAGTAGAATAATGTTTTCTAAA CTGTGTTAGACGGAGAACAACCACGCAGGGTGCAGAGATGCTGCTGAGCCTGAGCTGGAC TGAGAAAATCTAACGGATGTGCTGGGACTGCCAGGAAACACCCCAGCCTCCTCCTGGAAA AACTGAACAGCCCAATTAGAACTGCCTTGGAAAGGAAAGGAAAGAGAAAAGGAAAGGAAA GGGAATTCTGGGGACTCTAAAACACCTTGGTTGTTTCCTTCATTAAATAAACAGTACATT TTTAGTTTCAAACACTTAACTTACTATACATGTGATGCTACAATTTTCACTCTTACCACA GTTAACTCAGCAATTGAGAATTATTTTGGGGGGTTTCCGAAGGGGCTTAGAATGTGGTAT GAATGGGAGCGAAGCGTGAGTGAGAAATATTAGGTAAGAAATAGAAAAACTCCTTTCCTA TACATATATTTGGAAGGGAGCACTGAACTCTATGTTTCCAACCTTACTGCACTTAACTCT TATGGCCTTACCTTAAGGATGGATCTAAAATCCATCCCTTAGGTGGCTTCAGGTCAATCA TCGCTATTCTGCTAGTATTTTATGACTTCTCCATATATGGTAGAAAGAATAATGCCCCCT CCCCCTACAAAGACATCCACATCCTAATCTCTAGAATTTGTGAATATGTTACCTTCCGTG GCAAAGGAGAATTAACTTTGCAGGTGGAATTAAGATTGCTAATCAGCTGATCTTAAAATA GATTATCTAGGGAGGCCAATGTAATCACAGGGATCTCAAAAGCAGAAGACGGGCGGGGGG GGCGGGGCCGGGCGGGGTCAGCCAGGCCAGGTGGCTCACATCTGTCATCTGTAATCCCAG CACTTTGGGAGGCCAACGCAGGAGGATCACTTGAACCCAGGAGTTCAAGACCAGCCTGGG CAACATGGCAAAACCCCATCTCTACAAAAAAAAACAGAAAAAACAATTAGCCCAGAGTGG TGGTGCACACCTGCGGTCCCAGCTATGAAGCAGGAGGATCACTTGAGCCCAGGGGGTTTA GCAGTGAACTGAGATCATGCCACCACACTCCAGCGTGGGTGACAGAGCGAGACCCTGTCT CAAAAAACAACAAAACAAACAAAAAAATCCAAAAAACAAAAAAGTAGAAAACAGAGGCAG AAAAGACAGGCCAGGAAGAGATTCTCCTAGAAGCTACGGAAAAGAACACAACTTCACCAA CACCTTGATTTTAGACCAGTGAGATCCCGTCTGACTTCTCACAACCCTAACAACAACACA TTTCCTGTGTTTTACGCCACTAAATTTGTAGTAATTTGTTACAACAGAAAATAATAAACT AATATACCAGGCTTCTTCTAGTCCTTGGATTTCAGAAAAATTTTGACATCAGTAATTGCT ACTAAAATGACCCTATAACCCAGGACACTGCCAGTCTTGTGAACTGTTTGGTACTACTCC CTAGGAAGAAAAATACAGAAATTGAGAGTTTATTTGTATATAATTCAATTTCATGTCTGC TGAGTTTAATTATTAAAAACTTAGGCTTGTAATTTTATTTCTTCCATTTCATTTATCTAT AAATTTATGGTATTTTACAAAAGTACTGGCTGAGACAAACGGAGATTTTACTTTACTTTT TAAAAAAAGAAGACATTTACAAAAGAGAGGTGAAGCGCTGACAAGTTAAATCACTTGCCC AAGTTCAGAAAGTGATTCATCACCCAGTCATTAAATTAACAAATGTTTATGAAGGGCCTT CTACTCCAGACAGCAAGCTCCATGCTAGAGCTACTGTTCAGAACAAGACCCAGCAGAGCC CTGCCTCTCCGTGTGAGTCCCATTCTCCTTAGCGTCCCAGGAATCGCCCTAGATCGCCTC CCCAGCAGCGCTCCCCGCTGGTTACCTTCCCACCAGCATTCAATCCCAGGAAAACAAGCG CAGTGTGGACAGACCCGGCCCAGTACGCAAATGCCACACAAAAGGACAACGAAAGGAAGA AAAACACCAAGCACAGATTCTAGGGGCCGAGGGCTGAGCCACAACGCACCGCAACTCCGG AAAACTGGGCCCCGGACCTCAGCTCCCCTTCCTAAGCCAGGCTCCGCCCCTATTCCCGAC CCCGCCCACCGCGTCGTTGGCGTAATTCCCGCGACTCCCTCTCACCCGCCCGGGCTCCAC CTTCTGTAGGGGCTCCACCTTCTGTAGAAGCTCCGAGTGCCGCTCCAACGCGCTCGCGAA ACCGCCTGCGCGCGTCTTAGGCTCCTTGGCATTGGAACTACCACTTTCGGATCCACTCTC AGTGCCTACACCCCGAAAGGGCCTGAAGAAGAGAAACACTCGCAGAAAATGGCTCTCGGC AGCCACAGCACGGGTCCGACACAGCGCCGCCATGACTTCTTTACCTCTGACCTTTGACCT CCCCTCCGCAAGCGCGCGGGTCACGGGGCGGAGCTATGAGAGGTCCGCCCCCCGGACGCA GAGCTCTGGAGGCCAACGAGGCGTGTCTTCCTTTCATCTGGGAGTGGCGTGGGGAAGAAG AGACTTAAGCTAAAATTGGTGGGCTAAATAGTTGGAAAGGGGCCTGGTTAAGTTTTGCGT TAGAAGTGCGTTTAACTTGCAGGAATTTCGCCTTCCTGGGCATCCGTTGGACCCCATTGT ACTGTAAATTCTGCTAACGCGACGCTCGTTCTCCCGCCCTGCCGTCCCCCCTACATGGCC GCCAGCACTCGAGTTTGGGGTCTTCACTCAAATATGAGGGTCTCCTTGATTACCCTATTT AGAAGTGGAAGCCCAAATGCAGACTCTCTGGCACCTGTTTTTCTTAGTACCATGTAGCAC TTTCTAATATGCCACATATTAATATTAAATATTTAATAATATTTAGTGTCTACTCCCAAC TTTTTAAACTTTGAAAAGAGGAACTTTGCTGTAGGGTCCCTAGCACCAGGCACAGATTAG GGCTCACCCAACATTTGCCAAACCCTGCATCCAAGTTTGTCCTTTGCCACTTCTGCAGCC AGTCCACTCACGCCACAAAAATAGTTTTTCTGAAATGTTTTGACACCTCTAGATACCTAT TATCTAACTTAGGAGTTCAGAAGTTTTGGAATGTCCCTAAGTATTGCACCGCCGTAGGCC CCCACCCTCACTCTGGATTTTCTTTCCCTTTTCTCCTGCAGTGTTAATTCCCAAAATTTA CCCACCCTGTTCAAAACAGCCTAACATCATTCTTAAGTGTTTATTAATTAGTTGTCCGTC TATCTTTGACCCAGCAGTTTAATATTAATCCACAGTTAGTTTTATTTTGGGGGCACACAC CTTTCCAGTTCATTTGCAAGTACTTCGAGAGAAAGAATTTTTATGATCACAGACCCTATT TTAAGAATGCCTTGACTATGGGTTTTAAGCTTTTCTGATGCTCTCTAATGGTACAGATAG TGTTAAGAACACGAAGTACACTGATCTCAGAATGGTGCACAATTGTATGAATCACATAAA ATTATTACTAGCTAACTGTATGGTAGTCCTTACAAATTCATTAAATTCTCCAGGTGAGTT CTCCCTCTTGGCAGTTAAAACTGTTTATCTCCCGAGACTATTAATGGACTCTTGCCTAGA ACATTATTTTCTACGGATAGTGCTACTTCCACTTTTTTTCAGGAGAAAGTGTGGTAAATT GTAAAGAGCATGGCCAGTGGTCTTCAAGAACCCTCAGTCTGACTGGGCAGGGTGGCTTAC ACTTGTAATCCCAGCACTTTGTGAGGTTGAGGAGGGAGGATTGCTTGAGATGAGGAGTCC GAGACCAGCTTGGGCCATAGCAAGAACCAGTCTCTACCAAAAAATAGAAAAATCAGCCTG GGGCAGTGGTGCATGCCTGTAGTCCCGGCTACTTGGGAGGCTGATGGAGGAGGATCACTT GAGCCCAGGAGTTTGAGGCTGCAGTGAGCTATGTTCCTGCCACTTCACTCCAGCATGGGT GAAAAGTGCAAAACTCAAGTATCCGTAAAAACACACCCCTGGCGTGGTGGCTCACACCTG TAATCCCAGCACTTTGGGAGGCCAAGGAGGGCAGATCACCTGAAGTCAGGAGTTCGAGAT CAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGT GATGACACATGGCTGTAATCCCATCCACTCAGGAGGCTGAGGCAGGAGAATCACTTGAAC CCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACACCACTGTTCTCCAGCCTGGGTGACA GAGCGAGACTCCAGCTCAAAAAAAAAAAAAAAAAAAAAAAATGAGTAAGTTTGTATCAAA TGACTTCAAATTTGGCCTTAGTTCTGTCTTTGGTAGAGGATCAGAAGCATCAAATGAGAG GGACTGTAAAGAACTGAACAAGTCAATAGGGGGATGTCCGCATAACTTTCTCCTTGCCTA TACAAGTGCCAAGAGTAGCATCCTCTGTAATAGTGATGTTTTCACATACGCCATCTTAAG GATTCTGATCCTGCTGTAACCACTCCTTGCTTTATTAAATACAGGCCTGGCTGGGCAGCA GTGCACACCTTTAGTCTCAGCTACTCGGGAAGCTGAGGAGGGAACATCGCTTGAGCCCAG AAGTTTAGGGCCAGCCTGGGCAACACAGTGAGACCCCCACCTCAAAAAAGCCAAGGAAAG TGAACAGAAAATAGTTTCATTCTACTGCTAAGTTCAAGCCTAATACTTTACAGCTACTGG CTTTGGTCTTATCTATAAAATGGTGACACTGCCACATGCCTGAGTAAAGAGTTAAAGGTG ATGAGTGTAAGATGCCTGGGCACTTAATGAATAGTAGCTATTGACGGCTAGGTGGAGGTG ACCATGAGTTTACTAGAAATTCATGCCTCAACCATGTGTGCAAACCAAGAAGAAAGGATA GTGTCACAAAGTTCTTAGGATGTCGCTTCACCAGCTGGAAACTTCCATGGCCTGCAGCGC CTCTGCTGGAGTTTTGCTCATGCCTGCTGGGCTCATTCTGCCCACTCTGCCCAGTAGGCT GTGCTCATCTTGTGCTGCTGGCCCAGATCCCACACCTGCCAAGGGTGAGCCAGGCATGGG CTGGTGAGGGGTGCGTGAGCAAGTGAGTGCAGGTTCCAGCCACTGCGCCCAGCCAGGCAC ACCAGCTGCTGCAGCAGGGTGAGCAGCTACAGGCACCGGCTCTGTGCAAGGCTGCAGCTG GACCAGATGGACCACAACCAGCTTCTGCAGGCACCAGTGTCTGGGCAAGGGAAACGTGGT AAAACCCAAAAGCTCAGAGATGCCAGCAACCTCAGAGTCCCAAAGAGGGTGTTACAGCAT GTCACAGCCCTGGCTTGGGGAACCCCAAGGTGTGGGCTCCCAGAAGGGCTCAACTCTTCT CGTTGCCTGCAATGTGGTGACCGGCGGGGCGGGGAGGGGGGTTGGGGGGGGGACATTGTT GGGGGGTTGTTTCAGCCCGTTTGTGTTACAGCTCTTTCAGTCCCACCACCCCACTCCAGC CCATGGCTCCTCAGCTGGCCTGGCTCTGCTGCTGCCTCCTGTCATGTGGGGCAGCTGTCT GGTGCCGGTGAAAGGTGGGAAGGCTATAATGTTATAGCAGCTCTGGCTCAGGGAATCCCA AGGTCTGGGTCCCCAGAAGGGTCACCACTCTTCTCTCCTGCAGTCTGGGAGCGTGTCACC GCCCCAGCTTGGCAAGCCAGCCAGGAACATGTTACAGTTCCTTTTGCTCCCGCTGTTCAG CAGGTCCTGAGTTCTTGTCCTGTGTCCAGGAAGAATGAAGTCACATGGACAACCGTAGGG TGAGCAAGGCAGAGAGGAGCGTTATTGAATGACAGAACAGCACTCAGGAGACCCAAAGTG GTCCTTTCTGCAGGCAGGTTGTCCTGATGAGTGTTGAGTCTGGCTGAGTGTGGGGTTTTT ATGTGCTCAGAATGGAGGAAGGGTGGGCCTGGAAAAAACACCATCCGATTAGCCGAAATG CATTAATAGAGTTCTCGCTCTGGGTTGTGGGCTCTACCTAAAACTGGCAGCCTGGCCCCC AGGCTTCAGGCTGTCCCTGGCTTGAGGGTGGGGTTTCAACAGGGACCCACCCCTTCCCTC CTAGGAACCTGCCTCCTGCCACCATCAACATGCCATCCAGAGCACCCAGGCTGTCCACAC CAAGCTACCCTCAGCCCCTGGCCACCCTCCCATGCTCACTGGTGCCCATAGTTGGGAGGG GGCCGAGGTAGCAGGAACCTGACATGTCAGCACCACCCTGAGGATGCACACACCTGGCCA GGTTGTGACAGCACCCAAGCTCAGCCACAACTTTGCTCCGAACTGGAGCAGGCACTTCCA GGCCTGCATGGGCAGGGGACTTTCCAGGCCCCCGAGAGCACACAGATGCCTGGATCTGGA GCTGCAGCTGGGTGGCTGCAGCTGCACCCAGGAGCACAAGCTCCTGCCCTGCCAACATGG TAAGGCAGGGTTCCTGCTGGGATCACCTATTGCCGGCCCCTGCCACTTCTGCAGAGCCTG CAACCCCCCAGCCATGCTTCCCTTGCTGCAGCTGGTGTCCTTGCAGCAGCTGCTCAAGGA GGGCCACCACCATCAACAAGTCTGGAGATACCGGTTGGGAAGCTATTAGTATCACTCTAA AAATAGTCATTTCACCCATAGAAATGGATAAGATCATTAAGGGGATCATGTAGAAGATAA CAACAGATAGACAATAGCATTTAGGAGCTGGAAGAATTCTAATACTAAAAAATAGTCAAA ATGGAAAATAAGAACAGAGAATCAATTCTAGAAACCAAGGAGAAACTTTAAAGCATGCTG GAGAGTGGTAAAGTGAAAGATCACGTCCATTTACAAATATTCAAACAAAACTGTATTTGG CTTTTTCTATATGATAGAAGAACCACAAAATTAATAAAATAAACTACCAACCAACCTCAG TAACATCAAAATTACATGAGAGCTGGCAAGAATTTTAGTTGCCAAATAGCATTTATTTGA GTACAAAATCCTGGCAGGCAAAAGCACTTGCAGACCCGACTCTCTGAGAACTTACAAACA AAAAGTGAAAAGCTCTTAGTTCATTTTGAGTCAGAACAATAAGGAAATTATGAAATCTAA GATGTGCAGGTTTACTTAAAAGTGATAATGGTTTATATTAACTGTGGCCCACACAGGGTC TCTCTAATCTAATGAAAACAGGACAGTCACTGAAAATAAGGACTAATCAATGGCCAAATG TTTCTTCACTATGGGCAAAAATGTGATTTCTTCATCTGGGCTTTAAGAGCTATAAATAAA ACACATGGCCGGGTGCATGCCTATAGTCCTAGCTATTTGGGAAGCTAAGGCAGTAGGATT CCTTGACCCCAGGAGTTGGAGGTCAGCCAACTCTAAACAAACACAAACATCATTCTGACA AATGACCTTAATGTAGGATCTCTTTGGACACATCTTCAGCAAGCAGTCATTTAATAAATG CCTTCTGATAGGCAGAATGTAGCTGCTCATGGCTCTTTAAGTATCATATCCAGAATATGA AGGGTTTGGAGAGAAGTTGCATAATGGACTTGCCCCTTTCCTCAATGGGCAGGTAATGTA TACAAAAGAACCCATACCCAAATTATAGCATTTTTATTTTCCAATACTATACAAAAAATA GACTGTGCATATCTTAACAGATCCAGATCCAAATTAAATACTTTTTTTCTATTTCAAACT ATTCTAAGTTGCTAAGGTGATAATCCAGTTTTGAGCTCTACTCTCTTCCACTGACTACTT GGCTCTCATAAGCATAAGAATTCTTGCCCTATTTCCCACAAACTCCATAAATTGACATTT CTTTTTGTAAGAAGGGGATATTTTCTTCTACACTTGAGTCCTTACATCTGTGAGATTTCA TAAGTATCTGAGATTTCACACTCTTGCTATTTTCTTAGTGTCAAACACAAGAGGAACCAG GAACTGTTTCTGGCATTTCTACTAATTACTATGTTTCTCATTCTTTAAATATCTGTGAAT TCATAATATTGAATCTGCCACAAAAACCATTTTGAATATTTCTAAATTCATGTTTTTTTC TAAATCCATCCTCACTCTTTTTAATACTTCTTTCAAGGGGCAGAGTACTTTACAGTAGAT TACTTTGTTTCTTAGATTAAGTATAGGTAGATGTCTAGAAAAGTGATTCTCCATTATTTT CTTTCACAGCCACCCCCAATACCCACCTTCATCCACTCACCCCACTTGCCACCCCCATTT CTATCACTTTTCCCTTTTTGGGCAGAAAAGAGACTTGAGGGTATTTCACTCATCTAAAGA AATTGCCACTTTACTCCATTTTGCCTTGTTGAAAAGTTAGTAGCAGGGCAGGATGCTCAA GAAACAATGTGATCAAAAGAATATGTTTGAATTTTAAGAAGTAGACTAGTTCATAGAAAA AATAATTTAACACTTGAGTAAGCACAATATTTCTATAGAAAGACAGACTTCTACAGATCC ACTCCTCTGAGAAAATGCTTCAACAGCCTGTGCCTTAAAGCCCTTATTTAGAATATGTTA ATATGATACCATTAAGCAATAATTTAAGGATGGTTAAAAAAAAATTTTTTTTTTTTAAGC ATAGACTCCAGTTGATTCGGTACAACAAGCTGTTTCCAGACCACTGGTCTCATAATAAAT ATTGAGACCTATACTACTGATAGATGGAATTTATTAAGCTTTTCACATGTGATAGCACAT AGTTTTAATTGCATCCAAAGTACTAACAAAAACTCTAGCAATCAAGAATGGCAGCATGTT ATTTTATAACAATCAACACCTGTGGCTTTTAAAATTTGGTTTTCATAAGATAATTTATAC TGAAGTAAATCTAGCCATGCTTTTAAAAAATGCTTTAGGTCACTCCAAGCTTGGCAGTTA ACATTTGGCATAAACAATAATAAAACAATCACAATTTAATAAATAACAAATACAACATTG TAGGCCATAATCATATACAGTATAAGGAAAAGGTGGTAGTGTTGAGTAAGCAGTTATTAG AATAGAATACCTTGGCCTCTATGCAAATATGTCTAGACACTTTGATTCACTCAGCCCTGA CATTCAGTTTTCAAAGTAGGAGACAGGTTCTACAGTATCATTTTACAGTTTCCAACACAT TGAAAACAAGTAGAAAATGATGAGTTGATTTTTATTAATGCATTACATCCTCAAGAGTTA TCACCAACCCCTCAGTATAAAAAATTTTCAAGTTATATTAGTCATATAACTTGGTGTGCT TATTTTAAATAGTGCTAAATGGATTAAGTGAAGACAACAATGGTTCCCCTAATGTGATTG ATATTGTCATTTTTACCAGCTTCTAGATCTAAACTTTCAGGCTTTTGAACTGAACATTGA TGACAGTGTTCATAGTTCAACCTACTGAACATACAGTGTGCTTGATTCAGAATGTTATTT TGTAGAAATTAAAATTTTAACCTGGTGAAAAATAAGTTGATATAAGTGGTATAATAAACA ATACACTGAAATGGTTACTGTCACAAACGGTGCTAAATAATGATATAGGAGGTTCCACTC TCAAGTCACCTAGAAGTTTGATTACATATTGTTACTTACAAAACTATAATAAATTGGATG CACAGCTGTTTACTTCAGTCTGGTGTCTTCAACCAAAATATGTACCTTATACCAAAACAA TGCTTATTCCAAAATATTTTTTGTAGCTAGTAGTTCTTTCCTTGGAGGTAAAGAAAATAC ACCCAAACTTTTAATTACCAGGATTCAGAATATTTAAGAGAACAATTTTAGTTAAGAATC AAATATACAGAGATTCAAAGAGGGGAAAAAAAGGAAATATTATAGAAGACAAAGGTCAAA CTGGCATTCCAGATCTGGAGCAATTTTGTAAAGCAGGAAAACAACTATGACAATCTGTAG CTTCTTAGATCATTATAGTGAATGTCCCCATTTACTATAAGTGTTTTTATAATGGTGTTT CCTAAATAAAGGAACATAAATGTACACTAAAGGGTGTTTCCCAAGAATAGAGGTGAAGAT ATTTTCATTTTGTTTAACCCACAAACTATTTGGTCAAAGGAATATGTAAAGCTAAATAAA AGCACATCTGGTAGAAATTCATGGCAATGCATGTTGACAAGATGTGCTTGGACCTCGCTT GCAGCATCTGGCAGTGGGTAGCAGAACAAAGGTAGGAATCTCACAGGCTCTCCTGTGTCT TTTCTGGAAGAGGCTCCGTGGTGGTGGCACTAGCATTTGCAGCCGAATTCAAGACTTCTC CAAAATCACCACCAGCAGGCTTGGTTCCCCCTACTTTAGACTTAAAAAAAAGTTCAAAAA AGGGAAAGACATTATGAAACATAAAACTAGCTGATTCTGCATAAAGTAACTCTAATTCAC TTTCAAGAACAAATACATCAGCAACCTTATAGCTCAGTGATTATTATATATGTATGGAAT TTAGTATTGTTGCAATGTTCAGTGTGGTTTTATAGTAAAACTCATGCATTCTCCCTTGCT GAAATATTCAGATTGGTAAATTCTACCCCTTCCCCTTTCCCCCTGCTCCTTGTTCTTCAC AGGAAGTCTGTCTAGAAAACTTTGTAAGGTCTATTATTTTAAAGTACCTAGTGAACTGTC TGTCTCTACACTTGCATAACATTTTGTATTGCATCGAATTGCTCATTTAGCTACACTCAT TCAAGAAATATTGAATACAACATGGGAAAGAAATATATGTTTTTTTCTCAGTTACAGTAT AAGCTTTCTAACCCTTTAATACTTAAAGTGTGGTTCAAGGACCTACAGACTCAACATTAC CTGGGAGCTTATTAGAAATGCAGGATCTCAGATATCCTTTCTACCCCACCCAACTCCAGC TACAGAATTGAAATCAACACTTGAACAAAATCCCTGAGTTGTTCATGTGCACATTATAGT TTGTGAAGCACTACTCCAACCTATCTGGCCTGAAATTTTGCCAATAAGCATTTATTTCAA TATATCTGCCTTGCATTTGTATAATACTTTTTCAAAACCCTTACACATGTCACTTTATCC TTTTCAATGCTAATCTGTATATGCTCTCTCACTGTTACACTGTCCAACAGGACAGCTAAC AGTAAGAAAACAGTCAGTGACCATGGATGCAAGAAGCTTATAGTGGGTTTGAACTTGACC TTGCTCTTAGCTCAATCTTAATTGAGTGGTCACAGACCCCTTATTTTCACTCTCATTCTT TTTGATCTACCATCCAAATTGTTTGGGAAATGCGAATAATGTGTGTTCATTGTTTATTAA ATTTATTAAAACACATTCCTTAATTATAGTATCAAATCTCCTTGCAGTTCAACATGTCTA AAACTGAACTCCTTCCCCCGACAACTAGCCCCTTCTCTATTCTTTTTTAACACTTTATAT GGCAATAGCACCTACCTAGCTGCCCCAGCCTGACACCTGGGGTTGTCCTGGATTCTTATC CAACTTGTTCTACATCCAATCAATCTTTTTTTTTTTCCGTGTCACTTCTCACTTCTAAAT AGCTCTAGACTTGGTCCCATTGCACTAACTTAATTCACTCTCCATCATCTTTGGCTTGGA GTACAACTCCGTCCTTCCATCTAATCTGCCTGTCTCCAATCGTTCTCCCCTTTGATGTGC AGGGCAGCCACTGATCTCTCTAACATTTACAGAAGAATGCACCACTTGGGTTGTTTAAAA CCCTTCAATGGCTTCCCATTGCCCCAAGTTCAAACTCTGCAATGTGGCCTACACATCTCT CTAGCTTCACCTCCTGCTCAATATCCTACAGCACAGTGAAGTTCTTGGTGGTCCTCAAAA GGGCCCTCAAACTTCAAACATTCCCTTCAACCTAAAATCCTCAATGGACATTACTGAGTC CTCTAAGAGGTCTTCTCTGACCTTCCCTTCCACCAAGCCAGGTGAACTTTCTGCCACTTG TCCTCATCACACCCTCAGCTTTTCACATCAGAACCCTTACCTCACTTTAGTTTCATTGGC CATTTAATTGTCTAGGCATCTTGCAGAAGGGGTCCATGTCTCTCTTGCTCACTGTGGTAA CTCTGGTGCCTAATACTGATTGACTGGCACATGGCAAATGCTCAGTAATCACAGATGAAT GAATCAACCCAAAATCTAAATGGACCTCATGTTTAATTAAATATAAATGTAATTTAACAA AATTATATCCCCAGCATGTAATTTTACAGCTTCCTTAGGATACTTGGGGTATCTGTTTAA TACGCTATCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTGGCTCTGTCAC CCAGGCTGGAGTGCAGTGGCATAATCGCTGCTCACTCTGCCTCCCGGGCTCAAGCGATCT TCCTACCTCAGCCTCCCGAGTAGGTGGGACTACAGGTGTATGCCAACACATCAGCTAATT TTTCTATCGTTTTTGGTAGAGACAGGGTTTTGCCATGTTTCCCAGGCTGGTCTCAAATTC CTGGACTCAAGTGATCTGCCTGCCTTGGCCTCACAAAGTGCTGGAATTACAGGTGTAAGC CACTGCGCCCAGCCAACATATTGTATGTTTTTAAATTACACTTTTTAATCTGAATGGTGC CTAGTCATATTTTAAAGCAGACTTCATTACAATTTATAGAATCTAAATATATTCAGGAGA GTATATAGTGAATGACCTGGAAGTTTCTCCTCATGTCCAATGTCAAAAACACATAAGATT CCTGGTTTTCCAATTTGCCATTTCAAAAATTAACACTTGGGGCAGATTTCAAGGAAAGGC TATAACAGTCCTAACAATATTGAGAACTGAATTTTAGTAATCCTTGACTTCCTGCAACTA CAGTTTGCTTTCAAATATATGACTTGGCACTAAGAAAAATAAAGCAGGTCTCTTGAAATG ACATAGAAGAATGACTCTTATATATATTGTTACTCATCAGATGCATATTGAGCAATGTGC CAAGAACTGTTCTAAGCCTTTGAGAAGTATCAGTGACCAAAAAGAACAGGTCCCTGCATT TATGGCTCACAAAGCACCCTGCTAGTGAGGGCTGAATGAATAAGCTGTAGGACTGTGTGT GTACAGTGTAACTCCTCTTCTGAAAAAACATTCATATGTCTGCATACAAACAGAAAAGGT ATGTACTAACGTTTGTATGTTCAAGAAAAAAAACGATCCAAACATCACACACCAAGGCGC CTGTCAGGGGGTGGGATGGTAGGGGAGGGATAGCATTAGGAGAAATACCTAATGTAGATG ACAGGTTGATGGGTGCAGTAAACCACCGTGGCACGTGTATACCTATGTAACAAGCCTGCA CATTCTGCACATGTATCCCAGAACTTAAAAGTATAATAAAAAAATAAATTAAAAAAAGAT CCAGATCACTGTAGAGTGTTTTATTTCAATAAATGTACCCTGCTTTTAAAGATGCATTTC GTGACTCAAAGTTCTGAAAGACTAAACTGAATATTAGTTTTTAAACTGACTGATATAAAA ACATTTAAGATACTAGTTTTAATCCTTAAAATATATCCCCTATAATTATCAGAGTTAGGA AGTAATGAAAATATGGGTTTTATACAAACTCCGTAGAGAGGGTCGAGGAATAGATGGGAA CTAGACAACTTTTGAGGTTGCCTGTGATCCTAAGAGTTGATGATTTTATAGCTTTGAATA TAATCTCAAAGATAATATAATTTACAAATCAATAAAGCTCATTATTATGGGGAAATGTTC ACCTCCACTAAAATCAAAGAAATCAAAAAATAAAAACAGTGAATCATAAACGATCATCAT GGCATCATTATAATAAAAAAAATGTCCAACAATTGAGGACTGAACAAATAATATCCATTA TAAGGTAATACAGGCCAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCC GAGGCGGGCGGATCACGAGGTCAGGAGATGGAGACCATTCTGGCTGACACAGTGAAACCC CATCTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGGCACGCGCCTGTAGTCCCAG CTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAAGTGGAGGTTGCAGTGAG CCAAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAAAAAA AAAAAAGTAATATACAAGCAGCCATTGCACATAATATTGAAAGAGAATACTTACTGATAC AGGAAAATGATTATGATGTATGGCTACTTCTTTTTTAAAGCGTAACAGCATAATAGCACA TACATCTATCACTGTCTGAGTGGTAGGACCAATTTTTTGTTTTCTTTCTTGTGCTTCCTA TATTCTTGTTAATTGTTGACAAGAAAGTTATATTAAATTTTGTCCACCTACAAAGGTACT TGAAATGAATAAAGCAAAAAGCAGCACAAATTTCTAAAGTGCCATTTCTTTGTAAATTGT ACATTTCCTTTCAGCATGTGGCATGCTGCCACACTACAGCATACACTAAAAAGATATTAA GTACATAACACCTTAAATGTCCACTAGTAACATAAGGAGTAAAGTTATTTACATTCTTTA GATATTTTTAGAAAGAAATATTAATGTCAATGATTTTCGCACAGCAAAGTTAATTAAGAC ACCAGGCAATGTATCAAAAAGACCCTGTTCATCTCTCTACTTGCCTTTAAGTTTTCGACC TTTTCTTCAAATGATTTAAAAGTTGGGGAGTTTCTATGGAGAGAAAAGAAAAACAAATAG TAAATACAAATACTGAAAAAAAATCCAACTAGTTTGAAAATATAATTGATTCCTCTTCAA CATTATTCTCAATCGGCAAAAGAACAGATATAATCTGTACCATATATGTGCAGGTACATA CAAGTATTTATAATGTAAGATTCTCAATTTCTGATCTAATATTTTAAGAGTATGCATTTG ATTCCATGAACAGGGCCAGTCTCAGACATAAGTAATATAGATATGGTCAAGTACGTGTGT AAGGAGAGGTAACGAAGCCGGGTAAAATAGCAATTCTGTCACTTCCCCAACCAACTTGTC ATGGTACAAGAAAATGCCACCATTAGATCAGTTTAATTTTGGTTAAGGTACTACGCTCTA AAATCCCTATTTTGATTCACATCTTCCCTGGCAGAATTTCTACATGAACACACATCACCT AAGTGGGACAAGCTTATGAGGTTCAATATCAGGGAGCAGCATAATAGACTGGGAAAGCAG GGACCAAAAAGAAGGGGGAGAAGCATAGAAACGGCTTTGCCTACTTCACAACTCTGTCCC AAAGGATGAGGAGAGCACGCTGAGCCCACAGGACATTCATTCATCCATGTTACATTCACA TCTATCCATATTAATTAAGGAGGATCATAGCGCCTTTGTCTCTCACAAAGGCGCTTTGGA AACAGGGTTTCCAATGCTGTTATCCTATCCAACTGACCTTGAATATCCTTCCTACTACCA AGATGAAAAATGCAAAGAAAGGAAAAGGGGTTTCTTCCTTCCCACGGTGGTGATGGCAGA ACAGTTAAGCCAACAGCTCTCAAAGTGTGGGCCCCAGACCAGCTGCTGCTGCAGCTATCA GGAAGTCATAAGCAATGCCAATTTTCAGGTCCCACCCCAACTCTACAGGATCAGAGGCTC TAGAGGTGGGGCCCAGCAAGCAGCGGTTTCACAAGCACTCCAAGTGATTTTGATGGACAC TTAAGTTTAAGCCAAGCACAGATTGTTAAAAATCCTCTAACTCTCTAGAGAGGTTAGGTG AGGTAATATCACTTGCAAGTGCTAATGAAAGCAGATAGTAGAATTAAATCATAGTTGGCT CCAAATGTCACAGTGGGATGGGGGAAGTGAAAATGGGAAGGATGAAGAAAAGGAGAATGT AACTAAAGCGAATGCAGACAGAGGTGGCGGGACAAAAGAAGGTTTGTTAACAAGTAGTGC TCACTTTGTGAACAGATTTCAGACAGGAAACAAAGGTTTTACAAAATAAAATAGAAATAA TTTTTTTAAAAACAAAATCAAAACATTTAACGGATCTCTTGCACCCATCCCAACATCAGA GGAAGTGTAGCTGAAAACTGATAGAGTGTTAAACACACAGCTTGTTTCAAGGGGAATTCT AGTTCCCTAATTCAGAACAGTTCAAGTTAAACATCTAAATAAAGAAAAATAAAGCATAAG ACCAACTACATTTCATAAAAATATACTTTACCTCATAGCAGGCATGCTAATTGAATGCTG AATGGAACGTATACTAAGAGGCAGCATTAAAAAGAGATAGAAATAAGGTTAGTATAGTGG TGCTTCAACATTATTAAAAGCTGACAAAACTTAGCTCCCCAGGAGCTTTATTCTCTTGGC GCCATGAAGAATTACCTACTTTTTGAGGTGGAGGGGATCAAAGTTATTCCAACATAATTT ACTTTTATTCAGGAGCCAATTAATTCCCAGGAGTTACTAGAGCTAACAATACCACCTTGC ATTTTTACAGCACTTTGAAAACTAAAGTGCTTTCACCCGGAGCTGTAAGGCATATAGGTG TTAAATGAGTTACCGTAGGTCACAGCAGAATCAAGAATAGAACTTGGGTCTAATTCAGTG TTTATCGCCTCCCCTCAAAAATGAAGCATGCACACACACACATACACACATACACACACA AGCAAGGCCAGGGAAGGGCTCTTAGTAAGACAAGGAGGCAACTGCCCACTCAAGGACAAT GCAGTTCACTGACCACTCAGGTTCAAGGTTACCTACTCTTAGCCATCTCCCATAAAGACC ACCTCATGAGATGAGAGTGCCTTCATTCCTAGGCTCGTAAAATGATTGTATTCTGCTAAT ATTGTTACTATGCTTATAATAGTTTGACCACTGGCACGACTTTGGTAAATAAACTTTCCT TTGGGTAAAGTGTATAGGTTCAAGGTATTAATTCTCAGTTATATTTAAATATTTTGTGCG CTTATGATTTCCTTTTCTTAAAGACTCATTTGGTACAAATGATAACGTGTCTTCAATGTA GGTCCTCAAATCTAATTTTGCATTAATATCTGATAACATGGAGAATGATTGTGATATATG TCAAATATGCTGGCAATCTGTGTAATCAGGATTATCAATGAAATATTTAAACACCTCTGT ACTTGATGTCTTACATAACAGGAAAAGATGCATGTAACTCAGTATTCTCTCTATCCTACA ATGGTGGTCAATACCTAGGGTATAAGAGTATAATAATCTATTCTGGGAGGAATTTGATAA TTCTTTTCCTACTTTGGATCTATCAAAGTGTGCTGGTCCCAATCTCTAAATTTACAACAC CAGAACTCTAAGTATCACCTGTTCTTCCTCAGACCCTTCTGCTGAAGCTGCCTGGAATAG TCACATTGCCACAAACCACCTTCTACCATAACTGATATGATAGGTGGATCAGTGGAGCAC CACCCACCACTGCTAACCTCCCAGTGGCCTACAAATTGTTTGGAATGTATGAAAAATGAA GGAGTGAAGACAATTAAGACTCTTATCCTAGCATATTGTAATTAGGACACTAAGCTGCTG GACACTTAGATGTTGAAGAGGATCTGGTGGGACCAGGTGAAAGCTGACAGAACACAGAGG AAACCAGTTCCCAAAGAAAGAATCGAATATAAGCACACAGAGAGGTAGAGCAGATGAGGT CAGGAGAGGTGATCATGCAGGGAATCCAGCAGGATGGAAGAGGAATAGGTTTCTTGGTTT CAATAATAGAAGCTACTTCAATTTCCCAGTTGATGGAGCTGGTTTGGGTGGAGCCTGGCC TTGCTTTCTTTTCTCTCCTTGAATTACAAAAAAACTTTGTATTTGTGCAACACATTCTTC TTTTTAGGTGAGCTAAAAGTTACATAGCTTTCTGTTCCTAATAATCAAAACTCTTCATTA GGACATTCATTTTGGCAGAAATCGCTGAAAAAGAAGGTAATGGCCAAATATGTGATAAAT TCCTTGTCCCGGGGACCCACACATTGAATTTGGTAGTATCAACAAAATGTGGAAACAGGT GGATAAGTAAGTGCAAATTTCAGAATTTCACAGCTAATTCTAGTCACTGTCCCTAAGAAC CCATGTACAATATCACTTCCTCCAGCAGTGGATCGGTTGGGCTCTATACCACTTTACCTA GCATGTACCTACTAAATATGTTTCAGTGGTAATATATAAGGAAAGGCAAGGAAGTGACTA GACTGTTTATTTTGTGAAAAAAATCACTGAAATGAATTTGGTGTTGAGCACTTTTCTGTA TGCATTATATCACACTTGAAGATAAATATACCCATTAAACAGAATAAAATCAGTTAACAG AGTCAAAGTCAAGGTCTCTCTGCTTTTATGGTAGCTATTTTATAGTAGGAAGAAAAGGAG CACACATCAGCTTCAATTCTATCTGGTTGCTGGATCCTCCCCATAATCCATAGTTAGATG AAATTCAATTTTGTTGGTAACTAGTTGTAATCTAACTATAGGGTGGCTGTTCTTTCATTT CTGGCTTCTCTATGGCAAGTTACACAAAGCTTCAACTTGCTCATCATTTTCAGTTTCATT CAAGCTTAAATGTAATATGGAAACCTTCAAAAGTAAAAAGTCATGTTGCTACGGGACCAG AATCATCTCTAATAGATAGGTTGTAAGAATCGGTTACCATCTATAAGGCACATTTTGTTA AAAATGTTGCATCTTATTTGTAACCCCCAAATACATTAATCTGTAATCAAACTAGGAATG CAAACATGGGCTCCTCAAAACACTGAAAAAAAAAATCAGGATAATCTGATTCTCACTAAG TACTTTTCAATCTCACACTGCATTTACTCTTACTTTGAAAAAGTCATTTTTTTAAAACAG CTGAATTGATTTTTAAAAAATATTCCTTGTTTCTAACAGTTATCTGATGCTTTCATGCTC AATAATAATAAGAGAGGAGGGGGTAGAGGGAGGATAAGGAAGGAAGTAGCAGCAGCGGGA GGAGGAGAAGGGAAAGTTAATGGCTAACATGTTGGACTGCTTACTATATACCACGTATGC TTTTCACAGCTATTGATGTACTATTATTCCACTTTGCCCTCACACAATCTTTTGATGTTG GTGATCACAGCAGCTATTGTTCAAAGTGCTGGACAGTGCCTAGAGGGGCACTGTCTTAAA CCACCACTGCTCTGGGGAGGCCCAGGAGGACAGTGCAGGCTCCAGGACTAGGTGTGCTCG GTTCCAGTCCTGACCATCAGCCACTTATACCTGCTGTGCAACCTTGGGGAAGTCACTTAA TCTCTCTATGGCTCAGTTTCCTCATCTGTAATATCAAAAACAATAGCATCTGCTTCTGAG GTACTATTGTCTCGCTGGGCTTATAAATGTTAATTATTATTATAACACATGCTTTAATTG AAACATGAATTAGCATCTACTGTATATTATACTTTCACATATGCATAGAAAATATGCAAA CAGGAGGGGAAATATAAGCATATCACGTTGAAGCTTTCAAATTTCACATTGAAGCTTTCA AATTTCAGCATTATTTTGGTTTTTAGCTCCACCCCTATAGTCTACAGCAATGCCTGGCAC ATAGTTAGCACTCAATAAATACTTTTGAGTGAAAGAATGAATGAATAAATGAATAAACAA TTTTGATAACTAAAATTGGGAATATGGGCATGAAACAGAGAAAAGTTCATTAAAGTGTTT CAAATTCTAATCAAAAGATATTCTTTTTCTGACACGAGGAAAGAGATCATTTCTTTTCCC ATTAAGTGGTGGAAGTTTTCAGCAAAAGGGAATTGTCTAGCAGGACTTTAATGAGCCCAA ACCAAATAAATATCTACAGGGGCACATGAAGAAACACACATTTAAAAAGGAGAAATTTTC TTTGGAAATAAAGGCAAAATTAATTAGCACTTCCTCTTAAATATACCAAAAATATGAGAC AAATGTGTCTACTGAATATTATAGTATGCTTTTAATAACACTAAAATTTTATGTTTAACC CTGGCACTGACTGCAATGAGAAGGTTCTTTTAAAGTTTCCCTCAAAATGCTAAAGGCATG AGTCAATACTTTCACATAGGCATAGAACATATGCAAACAGAGGGGAAATATAAGCATATC ACCTGAGGGAAAAGCAGGCTGCCCCAGAGGGCCTCCCAGGACAGCACTCATGACCACGTC CTCCTTGGCCTTGCTACCACCACACCTCATTCTCAGGACATCAAGAGCAGCTCTCTCTCT CTCTTCTCTATTTCCTTATACATCTCCCTCCCCTCAATCAAGGCATAAGGCAAATATCTA AATCCCAAGTGCTGATTTATCAACTGACTATGTAAAATAAAAACTGTTGCTGAGTCTAAC ACATTCAGGTTGGCAAAACTGCTGCATTTTCTCCTTCTATATCCATAATTACATTAAGGA GTAAAATCACCGGCATAAGTTTGCCAGGTAAAATGGACCTAGAACAAACAGTGAGTGGGA TTAAGGACTAACCACCTACTTCATAGCACTTAGCAAAAGGAGCCTACTGTATCCACCTCC ATGGGAGAAAAGGACTTATTGCTGGAATTGTAACACTCAAATCTACAGCCTAAGCTCCCT TTCCTTGGGTAGTTCTTGAGGGAACGTGGCCAATATTTGCCTCTGTGACTCACATAATCT AAAAGATGTAGGTTTTCTTTATATGTGTCAACACATTAAATCAGAACACAATCAGGACTT CTTGGCCTTGAAATTATTTTTTTAAATGCCTTTACCTAACCTGTGATTTGCAAGAATTAC AAAGTTTAACTTTCAAAAGATAATCTCATTTCTTTCATTTCCAAATTTTAATCAAAAACC TTACTTTAACCCCTACATACTGATGGGCAATTAAATATTCATAAAAACTTAATATTTATT AAAAACAAGACTGAAAATGGTACAGCATAATCTTAATTATATTTTTTAAACAAAATGGAC AAAGTGACTGTGAAAGGAGCTAGAAAACAGTTGCAAAACATAATTTGTTGCTGATGAATT AATAAGACAGCACACACTGAGCCATATCTAGGTATGGCTTTAAGGTATAGAAAGGTATTC TTTAAAGGTATAGAAAAGTCTAGTGATATGTACTGAAGAAACATCATCCTCAATAGCCCT TACTTTTATATCTTACACTGATGTTTGCATCACATCGAACATTTTATAACCAGTACTGAT AAGGCTCTTCCATTCTTAACTTATCCCAAGTCCCCACTCTTCCCCTACTCCACTCTAAGA TTTTAAGCTTCATTCTAATAAAAGCCATGCGTTCTTTATGGTTATGCCCATGGAACCTGT CCACAGTAGACACTCTAAATGTTAGCAGAATGGGTGATGTGACTGGCTCTGTATTCAGTT ACTTATAGCACTTTTTAACTGAATGCCAACGATACACAATCACCTATCATTGGTTACTTG ATTTTTTAAGCATAATTTTAGCTTTAAATAGTTCAACATTTAGAGTTTATATATCCCTAT AATTTACTCTGACTTCCAGGGGTAAGTGTCACCAAGATAGGAGCTTTAAGTACCTGTTTG CTTACTTAAAAAGGCAAGCAGCTAGACTACCATGAGTGATTGCTTAAGAAAATAATCTGC ATCCATAGGAACAGAGATGAAGACTACTATATCATCCTTCCTGCTTATACTCTAAAGACT TTCCTCCACCTTAGTTTCCTCCAACAACTAATCAGATAATCAAAGAGTCTGCCTGGGAAA GAGAAAGGTTTCCTCAACATCACAAAGTCTCTTTCTATAAGGCATGGTTTGAGCTAACAT CTTTTTAATGTGCTTTTTTTAGCTTAATATTCTTTTCCCTTTTTCAAACCATGAAGTTGC CTTGTGTACATAAAGAATATAACAAGTGTAAAGAAAGAATAAAATCATAAAAACTATAAG CTAGTAAAACAAGTATTAAAAAGTGCAGAGTAGTGGCAGATTTTACCTTATGTATATTTT ACCACAACAACAAAAAAAAAGGTAGAGTAACCAATAGAAGATGGAAGACTAACATCAGGA GGCAGTACATATGCAGTCTGTTACAATTGTGTAATGAAACCCAGGTGAAGAATTCCAACA TCCTTACAAAAGTACCAAAGAAACAAAAGCATCAAAACAAACAAAGTCAGACATTAAAAG GGAGGAATTTTGCATGCCATGGTAAAGCTGCTTCTTTTTACCAAAGAAAAAAGTAAAAAA GAAATGTCAAAATCATTTCCATATCCCTTGAACCACAGTGTCAAATACTTCTTTTAATTT ATCAACTACCCATGGTATACAAGAAACCCTCCCTTGAAATTAGGAATGCACTAGAGAAAA AGATACTCTAAACGCAAGAAAATTATGTACTGGACAAACACGATCATCCAACGTAGCATG GTAATCTAATCTCAGCACACTTTTCTTATACAACTGCTGGACTGCAGTGATGGTTCAAAC TCTCCTTACCTAAAGGAATGTGAAAAGGCTTGCAATCTGTAAGAAGCCAGAGTAAGCATT AAAAAAGAAAGAAGTTCTGATAAATCTAAAACAATTAAATAACCTAAGTTTTAAACATAT AATGTTTTCCCTGGGCTCTAAACTGCTACACAATTCAGTCAGCATAGAGAAAATGAACAC CTAATAGATACATACATAATTGTCAAAAGAGTTCAAGAAAGCTATATTTATTACATTATG CTTAGACAATGACAGTCTAAATATAATGAGCGAGGAATTTGTTCTTTTGGTGTAAAGTAT AACACATAAATTGACCAAATCTATTCAACCAAGAAATTCTGGTTGTAAGATATACACTTT CCCCACAAATGCAAAACACGAAGCCATGCAATCTGAGCATTTTTTTTTAAACACAAATCT TGCATGCCAACAGAAGCACAGCTGACTTAAACCACATTTGTCATTTTCATCACTATCCTA ATCCACATGAGTGAAGGGGGGGCACAAAAGCACTGTGAAGTGGTTTTATAAAAATGGCAA GGAAAACTCTGCAGACTAATCTAAATGAAAAAAAAAAAAAGCAACAACTCAAAATCAAGA TTTTGGCCTAAGCATGAACATAGTTACAGCTTACCAGTTAGAATAAAACAGTGCACAAAT GAGCATGTTGTAATCACACCATGATATAAAATGTCACATATAGAACGTGAAGCCAAATCT GAATCGAAGCGTGCACTTCAGTGCTCCTGTAGTCATCCTTAGTAACACACCAGGCTCTGC CCACAATCACAAATTTGCAACCAAAGACATACTTACCCTGCATGATCATGAAGAACTAAA AAGACAAAGAAGTTCACAACCAGAATTTTTCAACAACCTTAAATGATCATCAGATGATCA TTTGATGTTAGAATGCTAGGCCTAGAAGACCTTAGATGAGCCTTCCAGGTACTGGTTTGA AGGAGTGCCCTCCCTCACTCTAACAGGAGTAGCTAGCATCAACTAGAGCCAAGGTCAGGA AACAGATGCAACAACAATAACATTTTAATTTGCGTCAGCTACTTAATGAGCAAGGAAAAA TGAGGACATACTTTACATCTTCCAGCTTTTTGGTGATGACTGAGCCAACAGACGAAAAAG CAGCTGAGGCCTTCTGTCCAGCCTGGGATAAGGTTTCAGATGTCTTCTTGTAACTATATT AAATTATAAACACACAGAGCAAAAGAAGGGTCAGCTCATCTTTTCTAATATCAATTGTTT CAAGTGCAGTGGTCACCACCTGCTGGAGAACTCTCAAAAAGAGAAAACATTTTTCAGAAC TTCTAAAATCCTTCATAACCAGCAGAGCGGCATCACCACATCTTCGTATGCTCAACCCTA AGCTCAGGCACAATCTTCTGCAGTGCCCTAGTCCAGCCAGAAAGACAGAGTCCTATAAAG GCAGGGCCAAAGAAGTCAAGGTAAGGGCTAAAAATAATCATCAAACCAAGATGAAAATAA GCAAAGGCCTGAAAGAACTCATACCTATTGTTCTTTTCTCACATAATCCAAACAAAACAA AAATGAAATCAAATTCCTCAGATGCCTTTGTCAACTTGATTTCCTAAAAAAGGGCCAGAA GCAATTAGTAGCTGGCGTAAGTAGGACCCATTTGTATTTTATTATCCAAATACATTTTAT GGGCATACTTTCTAAAAATTTTTGCATGTCTTTAGAGAGCTACCAAATACGGACATGATG GACTTTCAACAAAGTATGTAAAATATGCAATGCTTAAAATTATTCTAGTGTGGTATCTGC TATCACGCAAAGCTATAATTTACCACCTCCTTCCCAGCTACCTGGAGATTAGAGAAGAGA AAAGCAAAAACAAAAAAATGATGACAACAACAACAACAAAAAACAAAATAATATCGTACC TACCAAAACAATTCCCACATTATGGGAAAGAATGCTCAGGCATTTTTACTTACCCTGTCA AGATCAAATACCAATAAAAAAACATGGTTCATGGTAATACTGTTGAAAAAATAGTTTCCT GTATGTTTTCCCACTGCCAACTTAGATGGGTAGAAAATGGACCAAAAGACTGGGGACTCA AGTACTGTCATGTTAAATGCAGTTGGCCTCACTTCTGATAGTTAAATTGTAAAACAACTT CTGTGCTCACCAGCTCTGCAGATGGCTCTCAATACAGAAGACAGAGCAGTTCGGTTTCTG CTGCTAGAAGCTTGCTCCTCCTTGTGCCGGGAAACAAAACTGCATTATGATAATGCTATA TCATAGCATGTGTGGTCAAAAAGACAAAAAGCCTAAGGGATTGACCTCTGCCAAGAGCAT ATATCTGAGACTACGACCTGAGAATCTTTTGATACCTACACAACAAGGTTAAAAAAATAC ATTAATAATAATAATAAAGACTGGCTCCAGACCTGAGTTTGAATTCCCACTCCACATTTT GAGAGGTTTGTGACATGAAAACTTAATTTGTCTGAGCCTGTTTCCTTATCCAGGGTTATC TTGCCACCCATTCTTACTGGGTTATTCTGAGTACTAAAGGACAAAATGTACATATTTGTG GCAAGTCAATACATAACACTTATGGGATTTGAATTTTATTTCTCCAACTGGCTAGCTTTC TTTCTATTCCTTAGAATAAGTGGTCTGGAAAAATTGAAGTTACAAAAAAAGGCAGGCACA CTTGAAAATCAGAAAAAAAGGGTGCCGTGTCGTCCAAAGAAAAGCTGCTGAAGCATCCTT ATCCTCTTTTTCTTCCCCTCTCCAGACAAAAGGCACAACAGTGTCCTTTACACTCCCAAG GAAAGTGTATGATCAAGGAAACATACGCAGATGTTGCTGTCACGTCTTGCCACCCTTTGG CAATGTTCTGTTTTAGTTCCTGTAGAGAATTGATTCCAAGTTTCCGCTTGATCTCTGCTA GATGCTTCTCTTTTGCTGCTAACACTTGAGACAGAGTCTGGATTTCTTCTTCTACCTATG AGGAAGGGGTTTGGGGTAAGAATATAGCAAAAGTCATTCAGTAAGTTAAGATTATTACCA CAGAACTACATCCAAAATTCCAGTCATTAAACATTTTTTTGAATCATTTATCTTTCTCTC TAAAAACAATGTATAATGTTGTTGAGTAAACTGGTTACTTGCTGATCTCTCCTGTAGAGT TCTCTTTCCTCCTCCATGGGAGCTCTTTATAATCCCATCTTAAGCTGTTTTTGGCCTTCT CCTCTCTCCCTATACTTCCTTACTCAGCTATCTCATGTAGGTTTAGGACTCAAATTTCTA CACAGATAATACTTAATAAAGCACTCTAACATCCACTCTCCCGACCTGTGGGTCTGCCTT CCCAGCCTAGACATTTCTATCTGAATGCCTACAAAACTTGTATTTGTATACTAAATCAAA ATAATCTCCATCCCCTACCAAAACACACACAACCAAGCCAAACCCAAATCCAATCTCCTT GCATATTTGATATGAGTATATATACTGGATACATATACTCAGTCCCTGTGTCTGGCAAAG TCATGGCCATAATAAATCAAACCGCCTCCTCAGGAGATCCCTGCTCTCAAGGGTTTCATG TGAACCCCTTGATGCTGACTGCCCAGACTTGACTAGGTGGTTAGAGGTGGGCCCTGACCC ATGGACAGCCACCCATCAAGAGCCAGTGGATGAGCCCAGTGTGAAAAGAGGTGCTCAACT ATTCGTCTCTCTCACTCAGGAATCTAGTTTGAGAAGTGAGATGACATTGCAAGTAGAAGC TGAAAAAACTTGAAGAAGCCTTGAGGTATAGGTAGGCTACAGTGAGATTATGAGAGGTAT GGAAAGCTTAAATATGCTTGAGGAATCTAAAACTGTAAGCAGAAGCTATGAAGAAAAGGA AAAAATGGACAGAGTAGAACAAAAGGCTAATCCAGGAAAACAGGGAAAATGGTAGACTCT CTATTTCAGAAACAGGGAAAAGGGTGGACTGCCTATTTCAGAGAGAAATAGACACCATGT GGAAGAGACTTTAGGTCCCAGGAAATTGAAAATCTAGGTCCCTAAAGTATATCCATTAAC ATTCAAGACCCTCAGAGAAATGCGTCTCCTGGCTTGTTGCAAAGCCATATTTTCAGCCCC AACCTGCACGGTATTTCTATGATTTCAAAGACAACATGCCCTTTAAAAATAACATAGAGT ATTGCTCAGTCAAATGTTTTCACAGATGTTTAAGTCTTTAGAGAACACAAAACAAAGAAA ATTAGTGCAACGGAGAAAAGGATAAATCAAATGTGATGCAGCTGCCAAGAAAAAAAAAAA AAGAAGAAAAAGAACCTACAACACCACTCTCAGATAAGATTAACTGGAACAGAGGTCCCT CAGAACAAATAAATAATCCCCTGTGCTTGTCAGAGTCACAAGTACTGGACCCAGTTTTGT AAGTCACATTTTAAGATGTACATTGACGAAGTGGAATACGAGAAGAAAAGGACAAAAAAA GAGGAAAGAATAAGGTTCAAAATTAAGTAAATTAAATGATTTGCCCAAAGTCATCAAACA AATAATGTAGGAACCAGAATTCCTATCTAGGTTTTCTGAATGCACGTCTCAGTTTACTGG CTGAATTCTCATGTACACTCTCTTAAGCTTCCCACTTCCTCTGTCTCTACTTCAGGCTCC AAAGCTTCAGACACTTCTAAGAATAGACTTAAATGGTAAGTTTCCCACCCCTTAGCACTT CTCTGAGGTACTCACTTCCTCTAATGAAAGCTGCAAAGACAAACCACTCTAAATCTTTCT GAACAATGCACAACACAGTATATTCCCCACCTTTGTTGGTTAGCTTGTGCTGCTAACACA CCTAGCCCAGCACATCATGGCTGCGATTCCTTAATTCAATATATACATGTAAAACAGAGT GACTTTAAAAGCATAAAGAGCATGATTAAGAATCTCTGATGTGTCTATCACTATATACAA AGATCAACTCAAAATGGACTAAGGACCCAAAACCATAAAACTACTAGAAGAAAACATAGG AGAAACACTTCAGGGCATTGGTCTAGACAAAGATTTTATGGCTAAGACCTCAGAAACACA GGCAACAAAAACAAAAATAGACAAATGGGACTAAATTCAAGGAAATCATCAACAGAGTGA AGAGATAACCTGTAGAATGGGAGAGAACATTTGCAAACTATTCATCTGACAAGGGACTAA TATCCAAAATATACAAGGAACTCAATTCAACAACAAAACAAACAAGCAATCCCATTTAAA AAGTGGGCAAAGGATCTAAATAGACATTTCTCAGAAGAGACATATAAATGGCCAACAAAT ATATTAAAAATGCTCAACATCACTAATCATCAGGGAAATGCAAATCAAAATCAAAATGAG GTATCACCTCACACCTGTTATTATGCCTGTTATCAAAAAACCAAAAAATAACAGATGCTG GCAAGGATCCAGAGAAGATGAAACTCTTATACACTGTTGCTGGGAATATAAATTAGTACA GCCACTATGAAAAACAGTATGGAGGTTTCTCAGAAAAACTTAAAATAGAAATACCACATA ATCCAGCAATCCCACTACTGGGTTACTTATCCAAAGGAAAGGAAATCAGTGTATCAAAGG GTACCTACACCCCCACGTTTATTGCAGCACTATTTACAATACCCAAGTGTCCATCAACAG GTGAATGGATAAAGAAAATGTGGTATACACAATGGAATACAATTCTGCCATAAAAAAGAA TGAAATCCTGTAATTTGCAGCAACATGGATGAGCCTAGAGAACAATACGTTAAGCAGAAT AAATCAGGCACAGAAAGATAAATACTGCATGTTCTTACTCACATGTGGACGCCAAGAAAA AACTCTGAACCCATCTAAGTAGAGAGTAAAATTGTGGGTGTTAGAGGTTGGGAAAGGGAG GATGCCTACAGGTTGTGCTTCAAACGACACTGTCATGAAAGTAAAAGACAACCAACAGAA TGGGGAAAATATTGGCAAATTACATACCTAATAAGAGTCTAGTATCTAGAACATATAAAG AAACTTACAACTCAATAAAAAGACAATCCAATTAGAAAATGGGCAAAGGACTTAAATAGA CATTTCTCCCAAGATATACAAATGACCAATAAGCACATGAAAAGATGCTTAACACCATTC ATTAGTAATTTGAGAAATGCAAATCAAAACCACAAGGAGATACCACTTCATACCCATTAG GATGGTTACAATTAAAAAAAACAGAGATTAATAAGTGTTGGCAAGGATGTGGAGAAATTG GAACCCTCAGACACAGCTGGTGAGAATGTAAAATGAAGTTGGGCAGCAAAGCAGTTTGAC AGCTCCTCAAAAAGTTAAACATAGAGCTACCATATGACCCAGCAACTCCACTCCTAGGTA TATATAACAAAGAGAATTGAAAACACATCCAGGCTGGGTGCAATGGCTCACGGCTGTAAT CCCAGCACTTTGGGAGGCCAAGGTGGACAGATCACTTGAGGTCAGGGGTTTGAGACCAGC CTGGCTAACATGGTGAAACCCCATACTACTAAAACACAAAAATTAGCCAGGCATGGTGGT GGTGTGCCTATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTCAACCTAGG AGGCAGAGGTTGCAGTGAGCTGAGATCATGCTACTACACTCCAGCCTGGGCAACAGAGCA AGACTCTTCTCAAAAAACAAACAAGCAACAATAAAAAGAAAACACACATCCATACAAAAA GCTGTACACAATTGCTTACAGCGGCATTATTCATAACAGTCCTAAAGTTCAGCCACTGTG GAACACAATTTGGATACTTCTCAAAGAACTTAATACAGAGCTACCATTCAATGGCAGCAA TCCCATTACTGGGTATAGAAATTGTTCTACCAAAAAAACACCTGCACTCATATGTTTATT GCATCACTATTCACAATAGCAAAGACATGAAACCAACCCCGGTGCCCACTGTCCAATGTG GTACATATACATCATGGAATACTATGCAGCCCCTAAAAAGTACAAAATCATGTCCTTTGC TGCAACATGGATACAGCTGGAGGCCATCTTCCTAATCAAATTAACACAAAAATGGAAAAC CAAATACCACATGTTCTGACTTATAAGTGGGAGCTAAACATTGGGTATACACAGACACAA AGATGGGAACACTAAACACTGGGGATTCCAGAAGTGGAGAGGGAGAGTTGGGGGAAAGAG CTGAAAAACCATGTTCACTACTTGGGCAACAGGATCATTAGAAGCCCAAACCTCAACATC ATGAGGCATTACCATGTAACAAACCCGCACATGTACCCCCTGAATCTAAAATTTTTTAAA TAAAAAATTTAAGTTTAAAAATGTTTTAAAAGGGACTATAAAGAAAATGAAAAGGAAAAT CCACAGAATGGGAGAAAATATTTACAAATCATATAGCTGGTAACTTCATTTGTTAAATAA AGACTATGTTTCCTCTTCCATCAATCATAATAGCACCTGCCCCGTAAGACTGTTGTAATA ATTAATGAAATAATGCATGTAAAGAGCTCAGTTTAACGCCTCCCACACAGCATGTAGTCT ATAGACATTAGGTGCTATTACTATTATTTTTATTTTGTTGATAATAAAACAATACTGAGA ACTGTCAAGGATTTGAAAAAAAATGCTCTTTCAAAACACTGTAAGAAATATGCTGGATAG CATTTTGGCCATGTTGCTATATACTCTTAAAAACCATTAGACCCAGGCATAATGCTACTT CCAGGACTTTATCCTAAAGCGCTAATTAAAGAAGTGCATAAAAACTTACATGAAGGTATT TTCATCAAACTATTATTCATAATAGCAAAAAATGGAAACAATCCAAATGTTTATAAATAA TATAAATTAAAAATGAGCTTGCGGAAATTCAAAATGGACTACGCAGCAATTTAAAATGAG GTTGCACAAGAGTATATTGGCATAAAAATGTTTTTGAAAATCAGTTAAGTGGGAAAAGGT TATCTGTATTCTAATGCCCTCTACAAATATAAAAATATATGGCTGGGCATGGTGGCCCAT GCCTGTAATCCCAGGACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGTTCAGGAGTTC AAGACCAGCCTGGCCTACATGACAAAACCCCATCTCTGCTAAAAATACAGAAATTAGCTG GGCATGGTGGCACACGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCT TGAACCTGGGAGGCAGAGGTTGCAGTGAGTCAAGATTATGCCACCACACTCCAGCCTGGG CAACAACAGAGTGAAACTCTGTCTCAAAAAACAAAACAAAACAAAAAAACAACCACACAA ATGGTTTATCACCCATCTGCCTTACCCATTCTATCCCCACCTTGTTTATAAAACTTTGGG CGAAAAAATGAGTAGTACAAACAGACAGAAGATCATAGAGACGACTTGAACAATACCATA CATCAACTGGACCTAACACATATATGTACAGAACAGCTCACCCCAAATTAGTAGAAATAC ACTGTTCTCAAATGCACATGAAACATTCTCCAGGACAGAGTATACGTTAGGCAACAAAAC AAGTCTCAATAAACTTAAAGTCATACAAAGCACCTTTTCCAACCACCACCATGAAACTGG AAATCAAAAACAAGAGGAAAACCAGAAAATTCACAACTATGTAATAATCAAACCACACAC TTTTAAACAACCAATGGGCCAAAAAAGAAGTCACAAAGGAAATTAGAAAACACCTTGAAA TGAAGGAAAACAAAAACAGTGTATTAAAACTTTTGGGATGCAGTTGAAGAACTGTCAGTA AGAAATGTATAGTTATAAATGCCTACATTAAAAAAAATCTCAATAACCTAACTCTACACC TTAAGGAATTAGAGAAAAATTTAAAAAATAGAAAACTACACCCAAAGCTAAGAGAAGGAA GGGAATAAGGAAGAGATTAGATATTAGAGTAAAGATAAAATGGACAAGAGGAAACAATAG AGAGAATGAATAAAAGCAATAATTCATTCTTTAAAAAGATCAACAGTGCATTAAGGGTTA AAAAAAAGAAAAAGACAGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGA GGCCAAGGCGGGCAGATCACCTGAGGTGAGGAGTTGGAGACCAGTCATGCCAACACACTG AAACCCCGTCTCTACCAAAAATACAAAAATTAGCTGGGAGTGGTGGCACGTGCCTGTAAT CCCAGCTATTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCA GTGAGACGAGATCGCACCATTGCACTCCAGCCTGGGCAACGGAGTGAGGCTCCATCTCAA AACAAACAAAAAAAAAGAAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCTCGTCTCT ACTAAAAATACAAAAATTAGTCAGGCGTGGTGGTGCACGCCTGTAGTCCCAGCTACCAGG GAGGCTGAGGTACAAGAATTGCTTGAACCCTGGAGGCAGAGGCTGCAGTGTGCCAAGACT GCTGCCACTGCACTCCAGCCACCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAA AGAAAAGAAAAAGATGAGTGAAATTGACAAACCTATAGCTAGACTGACCGAAAAAAAAAA AAGAGAGAGAAGGCATAAATAACTAAAATCAAATGAAAGTGGGGACATTAACTAACCTTA TAGAAACAGAAAGGATTATAAAAGAATATTATGAGCAATTGTACACCAACATACTAGATA GTCTAGAGTAAATGGACAAATGCATAGAAATATACAAATGACTAAACTGACCCAACAAAA TAGAAGAAATCTGAACAAGTAAAGAGATTGAACAAGTATCAAAAATCTCCCAAAGAAAAG TGTAAAAGTAGATAGCTTCAATGGTTAATTCTACCAAACATTTAAAGAATGGACAAACCT TTTCAAACTCTTCTAAAAAACCAGAAGATGGTAGAACACTTTCCAACTCATCTAAGAAGC CAGCATTACCCTATTTACCAAAGCCAGAGAATGATATCACAAGAAAACAGCAGCCCATAT CTCCTATGAATATCCAGCAGCATATTAAAAGGATTATAAAACATGACCAAGTGGAATATA TCCTAGGAATGCAAGGATGATTCAACACATGAAAATCAACCAGTGTTATATACCACATTA ATATAGTAAAGGGGAAAAACACAATCATTTCAATAGGTGAAAAAAAAAGCATTTCATAAA AATCCAATACTCTTTCATGAAAAAAAAAACCCACTAAAACTAGGAATAAAAGAGAACTTC CTCAACGCAAGTGCATTTGTGAAAAAAATGACAGCTAATATCATACTTATGGTTAAAGAC TGAAAGCTTTCCCCATAAGATCAGAAAAAAAGACAGGGATACCCATTTTTACCATTTTTA CACAATATTGTACTGAAGAGTTTAGCCAAAGCAGTTAGACAAGAAAAATAAATTAAAGGC ATTCAAATTGGAAAGGAAAAGTAAAACGATGTTTAATCACAGATGACATGATTTCATATA TAGAAAATCCTAAAGAATCCACAAAAAAGGCCAGGTGCGGTGGCTCATGCCTGTAATCCC AGCACTTTGGGAGGCCGAGGCAGGCAGAACACCTGAGGTTGGGAGTTCACAACCAGCTGA CCAATATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTAGTGGCACA TTCGTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGACAATCGCTTGAACCTGGGAGGT GGAGGTTGCAGTGAGCCAAGATCATGCCATTGCATTCCAGCCTGGGCAACAAGAGTGAAA CTCCATACCTTCCCCCCCACCGCCCCCCCCAAAAAAAAAAGAATCCACAAAAAAATCTAT TCAAGAGTGGTTGTGGTGGCTTATGCCTGTAATCCCAGCACTTTGAGAGGCCTTGGCAGG AGGATCACTTGAGTCCAGAAACATAGCAAGACCCCACCTCTACTGAAAAATAAAAAAATT AACCAGGCAGATGGTGGCAAGCGCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGGAG GATCACTTGAGCTGGGAGGTCAAGGCTGCCCCGAGCCATGATCACATCACTGCACTCTAG CATGGGTGACAGAGCAATACCTGTCTCAAAAAAATTTTTTTAAATATATTTGAGCTCATA AATTCAACAAAGCTGCAAAATATAAGATCAAGATATAATATTCAGTTATGTTTCTACATA ATAGCAATAAACCACCTGAAAAGAAAATTTAAAAAAAATCCATTTACAATCACATCAACA AGAATAAAACACTTAGGAATAAATATAACTAAGGAAGTATAAGACTCGTACATAGAAAAA TGTTTTGTACATTGCTAAAGTAAAATAAGAACTAAATAAATGGAAAGACATTTCATGTTC ATGGACTGGAAGACTTAATATTGTTAAGATGGCAATACTCACCAAGTCAATCTATAAACT GAACGCGAGCCCTATCAAAATGCCAACAGCATTTTTGTGTGGGTGGAAAAGCAGATTCTG AAATTCATATGGAATTGCAAGGAACCTTGAATAACAATTTTTAAAAAGAAGAAAAAGGTA AAGAACGCATATTTCTGGATTTCAAACTTACTACAAAGCTATAGTAATCAAAATAGTGTG ATACTGTCAAAAGAAAAGACATATAGATGAATGAATCTGAATCCAGAGTCCAGAAATAAA CCTATACATCTATGGTTAACTGATTTTTTTTCTTTTTTAACAAGGATGCCACGAGCATTC ACTGGGGAAAACTAGCCACATGCAAAAGAATGAAGTTAGATCCCTACCAAAACCATATAC GCTAATTAACTCAAAATGGATCAAGGGCTTAAATCTTAAGAGCCAACACTATAAAAGTCT TAGACAAAAACATAGGGGTAAATCTTTATCATCTAGGATTTAGAAATGGATTCTTAGATA TCACACCAAAAGCACAAACCAAAACCATAATGAGATATCACTTCACACCCACTAGGACTA CTATAATCAACAACACAGAAAATAACAAATGTTGCCAGGGATGTGGGGAAATTGCTGATG GGAATATTAAATGGTGTTAATACTGTGAAAACAGTTTGGTGCTTCCCAAAAAAACTTGAA ACATGGGCCAGGAACAGTGGCTCACATCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGG GAGGATCACGTGAGGCCAGGAGTTTGAAACCAGCTTGGGCAACATAGCAAAATCTCATCT CTATGAAAAATAAAAATTAAAAAATTTGCCAGGCATAATGGCATGTACCTGGAGTCCCAG CTACTCAGGAGGCTGAGGCAGGAGGATTGCTTGGCCCAGGAGTTCAACATTATAGTGAGC TATAATCATGCCACTGCACAATCACCAACCCACAAAATAGAGCAAGACCTTGTATCTTAA AAAAAAAGTTAAAAAAATTTTAAAACATTAAACATGGAACTACCACATGATGAAGCAATT CCATATCTAGGCATATATGAAAAAGAACTGAAACTAGGTACTCAAGCAAGTATTTGTTCA TAAAATGTTCCTAACTCACTACCCACCATAGTCAAAAGGTGAAAAATCACCCAAATGTCT ATGAATGGATAAATGGATAAACAAAATACAATAGATACATGTAATGGAATATTATTCAGT CATTAAACATAATGAAGCACAGATATGTGCTACACCATGAATCAACCTCAAAAACATGAA GGGAAAGAACCCAAATACATAAGGTTACATATTGTATGATTCCATTTATATGAAATAACC AGAAGACAGTTAAATCCATAGAGTCACAAAGCAAATTAGGTATTGCCAGGGGCTGAAGGA GGGGAGTAGTCAGGATTGAATGCTTAATGAATACAGGGATCTCTTTGGAGGTGAAGAAAA TGTGTGGAACTTGAAAGGGGTGGCAGCTGCACAACACTGTGAATGTTACATGTTACTGAA TTATACTCGTTAATTTTTTTGCCTGTAATCCCAGCACTTTGGGAGACCAAGGCAGGTGGA TCACTTAAGGTCAGGAGTTCGAAACCAGCCTGGCCAACATGGCGAAATCCATCTCTACTA AAAATACAAAAATTAGCTGAGCACAGTGGCAGACGCCTGTAATCCCAGCTACTCAGGAGG CTGAGGCAGGAGAATCACTTGAACCCAGGAGCCAGAGGTTGCAATGAGCCAAGATTGTGC CACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCGAAAAATAAAATATAATAA AATGGTTAATTTTTATGTTAAATGAATTTCATGGAAGAAGTTAGGAAAGAAAAAAGTAAG AAGGGAGGGAAAGGAGAGGAGGAATGGGGGGGAATGGCAGAGGGAGGGAGGGGGAGGGGG GGCGGAAAGAGAAAAAAGAGAAGCCAGAAGGGGAAGAAGGAGGGGAGGGAGGGAGGGGAA GGAAGAAAGAGAGGGGAAGGAAGGAAGGGAGAGAGGGGAGGGAAGGCAGGGTAGGGAAGG GAAGGGAGGGGAGGGAAGGAGGGAGCTGGAAGGAAGGAAAGGCGGAAGGAAGTTGGAAAG TGGCCATCTCTGCAACACAGCCAAGGGTAGAACAAAGTCACTGATGCACTGAAGAGCAAG TGTATCAGATGTCAGTGAAGTCCCTTAGAAGACATTCACTACTACTCCTCTCATTCATTT CCTGCTTCACACTCTACTTTTCACATCTATTTTACCCATATATACTTTTTTCTCATATAA AAACGAACCGATGTCACCCTCTTCTATCTCCTCTCCCCTACTCAAGACCTGCTGGAGAAG TAAACACATATGCTTTCTCTCCCCTGGAACTAACTATAAACATATCACCATGTACTTTAG AATCACAAATGACAGTACATTTTAAGTGCAAAAATAAAGTTGCAAAAGGAATGGTTCTTT ACCTTTGCAAGTTCTCTTCTTAGCTCTTCCTGCTCCTCTTCCGAGAGGGTCTCTGTGGCA CTGATCGTGGCAGCAACATCTTCTCCTTCCTCAGGGACTGGGTCTGTTCTCAGCAGACCT GGTTGGGGATTTAAACCATTTTTTAAAGTGCAAAATCTAAGTAAAATCCCTATTTAAGCT CCTCCACTGTCCTAGCCAGAATAAAGCCAATTAGAGTAGATCCACACATCTCATCTCTGG ATATTCAAATGACCTGGCTTTCTCAGCAAAGGACAAAAGAAAATCTGAGCTAACCACCGG AAACTACCAAGTAGACTCTGCCAAAATATGAATTTAGAAAATATAGCATTCTCTTAGCTT CTGTTCATAGTCTCAGTCACAATATAGTTATGGCAGAAGAGTGAAGGGCCCAAAATGAGA TCTTGCTGAGACTTTAAATTGCTGCAAAAGTAAATCAGTATAAATTAGATGAAAGATTTT AGCTCCTTCCCAGTAACCCAGGGCAGGAGTTTGCATATCTCTTCAGCTTGCTGTGGTAAT CAAAGCCAACATTTCATAAACTCAGTAAAGGAGTAACCACTGAATGAACTAAATGTCCTA AGTAAATTTTATTCTGTTTCTTTCCATTAGTGGAGGCAGAAAACATCTTCTTGTAAGTTC TTTTTTTGTTGTTTGTTTGTTTGTTTTAGGAGGTAGAGACAGGGTGTCGCTATGTTGCCC AAGCTGGTCTTGAACTCCTGGCTTCAAGCCATCATATATATATATGATGATATAGATGAT TATATCTATCTATATATATCTATATCTATATATCTATATCTATCTATCTATATATATATA TATCATCCAGATACCCTTATAAAAGAATACTAAGGTATATGTTCAGAGACATGACCAACA GCCACACAGAGACATTCTACACTACTGAAGACCAACCACACCGCACCCATTCCCCTTGGA ACGGAGCCTGTCAGGAAGAACAACTGGAGAGTGACCAGGAGGCAGCTGCCCCTCAGATCT CCCCTCTTTTCCTGCCCAACCCTCACCCACAGGCTAAGATGAGGCCAGAAAGGCACCCCA ACCTTGGGTGCAAAATTGAAGAGGCCACTAAAACACTCAATATAAATATCTTAATGCAGT ATTTTTTAAAAATCAAATTCAAAGAACCCATGATGAACAAAAATGCCAAAATTTTAAATT GAAGGATCAGTATTGCTGATACTTTGTCTCAAACTCCAAAATGGCTCTGCATGAACAGCA CTATTGGTAATCTCATCTTTATTTAAAATTGTGATATTTTATTCATGATTTTCTTTTACA TTAATTTTTAAAAATATTGTATTTGTATATTATTTGACGACTAAGCTTTTTGTCACCCCC TTCCTGGCCTCAGCTGCCTTACCCTAGGCTTCAGTTCAGTTTACAGATTTGGGATTACAA AGTCTCCTCTGGCAACAGATTTTTTTTTTTTTTTTTTTGCAAAGAAACCAGGGGAAGGTT TACTCCTCTGCCTGCTCTTCCTGCCAGTGAGCATCACAGCCACTGCAGTTGTTCCCTGCT ACCCCCCAGGACCATTTCTGAGAACTGCCAGTTCAGCCACAGCAGCAATGTGGCATCCTG CCCAATGCAAGGCGCCAGGGAGCAGACACAGAAGAAAAAGGAAGGAGAATAACCACACTG TGGAACAAGCAGCCAGCGTCGCAGCAAGCATTAGAGAATTACATGAGTCAATGAGATGAT GCTTATGTACATGGTGTACAAGTTACAAAGGCACTTGGTACAGGCTCTACTGTACACTCA CTGATTAATAGCAGTTAATAATTATAATAATAATCATCAGCATGGCAGCACCAAAATAGT GCCTACCTGGAAAGCACAGAACTGTTAAAGGCATAAAAGTAACACAAAAAATTCAAAAAC CACAAATCGGACTGGCAAAAAATATGATTAAGCTCTTGACTGAATATAAAATATTTAATA GGTACAATCAGCAAGTAGAAAAGCTCAATGCATAATTGCTTCCGCAGGTCTTCCTCTAAA ATATTTGTGAACAGACTGCCCAAATAATATTTCTATAATAGAAATCTGACTGTATCACTC TTCAGCTTAAAATCCTTTGGTGATTCCTTACTGTTTTCAAAGCAAAGTGTGACCCCTGAG GTTGGCAGGTAGCCCTTACTGGACCCGTCTCCTGCTAGCTGGCATTGGCACCTCTTACTC CAACTCCTGCCAAACCACACCGTGAACAACGTGCTGTACTATGTACTGTCAGAAACCATT TCCCAGCATCTGTGTGTGCTTGTAAATCTACCCTCTATGTCAGATTATGTGAAGAAAGTT GTATGAGATTGAAACTGAGAGTCAAGCATTCAAGTAACAATCATATAAGGCAACACAGTA AGAACCATAACAGAGCTACCTGTTAAACGTTATTTTATTTTTAATGTTTTGTACAGAACT CCCAGGTTCTCCAACTACAACAGATCTCCAAAACAAAACAAGCAAAACTCAGGTACCAAA CCATTACTTAAATAGCAAAGACTCTTTCATGCTTTTTTGATACACACTGTTTTGCAAATC TACTCAAACAAGGGGAGAAATACAGTATCTGACTGCTAACACAATGCTTTATGTATACTG CCCAATTCCAAAAAGAATCCAAGGGGATTCTGGTTCTATTCAAGTATGCGGCTAGGCTAT CAAGGAAAATAAATCTCTCAGAAAAGAGGATGACGGGTTGTCCAGTTGGCTTCAAGTCTG CCAGGATGACCTTGAGATTTTATATTCAGCATCTAAGAAAGTTGGTAATGACATGTTCTG CTCTTTCCACATTAGCCCGTAGGTGGCAGCAAATCATTATCATTAAAATTAAAAGGTGCA GTCTGGAAAAAAAAATTAGAAATTAAAGAACACCAAGGAAGAACAGAATGGTAGATACCA AAATCACCAGCAAAACATCACAGTCATGCCTTGAGAAAATTATTAACCACAGCCACCATG ACAGAGTGCATTCCATTTACAGACAAGTCCAAATTAAGTGTTTTAAATACTTATGTGCAA CACTTCTGTGAGGTGGGGATCCCTGTCACCACTTACAGATCAGGAACCTCAAGCTTACAG ACATTAAGCAACTTGCCCAGGTTAACACACCTAAATCTTTGGTGGAGGTCAGATTTTAAA CCTAGACGGTCTGATGTAAAAACAAATGCTTCACATCACTGATCTGAAAACAAAGACAAA AGTAGGAGGCTGATGGTCAGACCTGAAAGGTATCTAGAAGCAATAATAAGACCCTAAAAA GTGAAAGAATCTGGCAGACTAGATCAAAAGCAGTCTTCATTAATTCCAACTAAAGTTTCC CCAAACCTGGGAATCCAAATTTTGCCTTATATATTCGTCTAGATATGATCCTGTTTCTTG TATGTTCAGTAATGGTATAGGATTTAATATGAAAATAGAGTCTGGCTTTTGGGAGAAAAG ATTAATTTCTCATTCACAACATGAAAGGTGGAAAATAAGAACATTTAAAAGTATAGATTA TTGAAAACCATAATCCAAAACTTATTTGTTCATTAATTTTAATGTTGTTTTTTTTTTCTC AGAATCTGATGGAAAGCTGTTTTTAAAAGACAAAGATGGTGGGGAAAATACAATTAATAT CTACTGACATCTACTACACCAGCCACTGTGAGGGGAAGTCTACATGTTATCTTATAAAAA TAAAAACACCCCATAACCACCATCCGAGAGGAGTATTTTTTTTCCACCAGGAAACTGCGG TCCTCTAAGGCTATATAATTTGCCCAGAGTTACAGAGGCAGGATTAATACTTGGGTCTTT CTGTCTCTCGACTCAGCTCCATCACGAACATCTTAGAGAAACATCAATGATCATGGCAGG ACAAGGAAACAGGGCCTAGTCTTTCTCCATAGAAACGTTTTACTTTCCTGAGGGTCTAGG AACCTGTGGGGATCCCTGGTTTGAAAGTCACAGATAACATTATCAAACACAAGTGACTGA AAATGAGTGATAATTTCTTCCATCAGGTTATTAACATTTTAGCCATTGCCTTAGTTCTCT TCATCTAGCTGTGCAAACAGATTGTCAGCCTGTCTTCAGTTCCATCCATAGGATCCCTGA AGAGCTTTAGGTGGGGGAGTGACAAGTCTAGACTTGTCTTTGGAAAAGTCCTTCCAGCAA GCTGGGTATTGGGTGGCCTCCCCTGGGAAGGGTCTGGAGTCCACTGGCAGGGCAATGCAT CTCGCTGATTCCCAGCTGAGAGTTCTAGTGTCTCAGGGGTAAGGATGGAGAAGACAAGCA GAGACACATCCCATCAATCTGAAGATACTTTTTACATTTTACATCTTTGAGATGCACTGT ACAATTAATCAGCCAGTCATTGTGACATGGTTATCACCTGCAAACATGCTTCAAAATTTG CAAAATGGCTTAGAAAATGCCAGGTCCGGTTACAGACGTCTCTTAAGAAAGGCTGCACCA CAGACATTTTATGTGAGGAAAATAAATCAATAGAATAGACATAGATTACTCCAAGTTGAA TAGCAATTCAAATAAGTTAGATTATGGGTGTGAAGACATTTTAGGAAATGTTCTTTTTTA TTTTAGAAAATATGCACAGGAGTGTTATGATCAGTGTAAACGTCTGAATAAATCTAAAAA AGAACTTCAATAAATGTAAAAATTTTGGCCAGGCACAGTGGTTCATACCTGTAATCCCAG CACTTTGGGAGGCCAAGGTGGGAGGATCACTTGAGCCCAGGAGTTCGAGACCAGCCTAGG CAACAAAGTGAGATCCTGTCTCTACAAAAACTCAAAAACCATTAGCCGGGTATAGTGGCC TGCACCTGTAGTCCCAGCTACTCAGGAGGCTGTGGCGGGAGGATCGCTTGGGCCTAGGAG GTTGAAGCTGAATGAGCTGTGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGA CCCTGTCTCAAAACAACAACAACAAAAATTTTAATAAAAATTTTTAGGGGGCTGGGCATG GTGGCTCACACACACCTGTAATCCCAGCACTTTGGGAGGCAGAGACAGGCAGATCACTTG AGGCCAGGAGTTCAAGACCAGCCTGGGCAACGTGGTGAAACCCCATCTCTACTAAAAATA ATTTTTAAAAAAGATTTAAAACTTAAGTTATGATAAAGCAGGTTTTTTTTTAGTTTAACT ATTAGCATATTTTATACTTAATGAAACAAAAAATAATAGTAACATCTTACAATCTGTGGT GTCTTGGATTTGATGAAATACAACACTTCAAGACTTCAGAGTCCTTGTGAATAATGTGCG GAAGACAAAGTGGAAATGTGTGTGTGCGAGTGTGGTCAGAGCAGGGAAAGGCAGAGCAGA GTGGCCAAGAACCGGTAAGAGCTTAGTCCTGAACACATCTCTAGTTCTAGACTATAAAGT CCTGATGTCACTTTATCTCTCCATCTCAGAACTCACAGTGCCTAGAACAGTCAATGTTAA TATTGCATCTGAACTGAATTATTCTTTAAAGATTTAATTAAAGTAGCTCTCTCTTTACTT TCCCATGCATAACCACCCATTTGCCACATACTTTCACAAATTTCAACTGGGGAAAGCAGC AAAAGCGTTTTTACTAAAAATGTAGAACCTACACTTAAGCCAAAAATAAGAGTTTGAGGA GCGCCTCTCTCTGCTTGGGTGCAGCCCCAACCCCCCTTTGGAGCACCCACTTAAATGGTT ATCTTCCCTCTAGTTCTTCGTCTTTGACTTTTATTCCAATTATGACCAAGTGCTTCAAGA CTTTCTAAGATTATTGATTAAAAGCTTTTTGGCCATTGTCATACAATTTTAGATCTGAAA GAATTCTGAATCGTTTAAGTCAGCAGTCCCCAGTGTTTTTTGCACCAGGGACTGGTTTCA TGGAAGACAATTTTTCCACGGCGGTTGGGGGTTGATGATTTTGAGAGGAAACTGTTCCAC CTCAGATCATCAGGCATTAGATTCTCATAAGCAATGTGCAACCTAGATCCCTCGCATGTG TGGTTCACAATAGGGTTCATGCTCCTATGAGAATCTAATGCCACCACTGATCTGACAGGA GGCAGAGCTCAGGCGGTAATGCTCACTCGCCTGCCACTCACTGGTTCCTAACAGGCCACA GATGGGTACCAGTCCACCACCTGGGCGTTGGGGATCCCTGGTTTAAGTCAAATGCTTCAT TATATAAAGATGAGAAAACTGAGGACAGATTTTTACAAGAATAGGAAAAGACAAGATGAG CTTTGAAATTAGATGGTGTTGTGAGTTGAACTCTGCTGCCTTTAAAGATGTCTTCAATTT CCTAACCCCTGACAACAATGAATGTGTCTTTATTTGGAAACAGGATTTCTGCAGATGTAA TCAAGTTAAGATGAGGTCACACTGGATTAGTGAACTCTAATCCAATGGTTCATGTCCTTA TAAGAAGGAAATTTGAACGCAGAGACTCAGAGAAGAGATTATGTGAAGATACAGAGCGCA AAGCACAGAGAACACGCAGAGATTGGGGTGACATCACTACAGAACAAGGAACACCAAGGT CTGCAAGCAAACACCAGAAGCGAGGAGGCAGCAAGGATTCATTGCCCTGCACGTTTCACA GGGAGCAAGACCCTGCCAACGCCTTCATTTCAGATTTCTAACCTCCAGAACCGGGTGATA AGCCACCCAGAATGGCTACCGCAGCCCCAGGAGAATAATTCCGATGGAAAGGGGCATAAA CACTGATTCAGCCATTGACTAGTTGGTTGATCTTCTTTAATCACATTTATCTTCAAAGAG CCCCAAGCCCCTTACCTGCAAAAAATGGGTACACACAAGGATTTGCTGTTTCCCCCAGGT TCCATGCCCTATAACTTGTCCTGGCAATTGCTTCTCTCTCCTTTCGTCCTCCCTGAGTCT TGGCTCTCAGGTCTCACTTCCTCACTGCCCACTACTCTTCAACCCCCTGCAACCTTGTGG CTGCCCCTTCCACCTCCCTTCCACTAAGGACAATTCTGGGTCACTACCCTCATCTAGCCA CGCCAAGGCCATCTGACATTGCACTTCAGTCTGAAATCTCCATTCCTCTCCTCCCTCCTG GTTTTTCTCTTCCTACCTCTCTGAGACGTCATGGCTCCATCTCACTCTCTGGACATCCAC TTCACTCCTTGCCTCCAATCCTGCCCTCCTGCCTAGTTTGAGCTGTCACTATGTGTTGCT TAGATTCCTACCCCTAAGCTCCTTGCCAGTCTCTGACATCTGCAAATATTCCTCAACCTG CCCCAACAAAGAGCTTTCTAGAGTGCATATCTGACGACGCCACTCCCGTGCCTTAAGTCC TTTGATGGCTTCCCAGCTTCTTGCAAAGCTCCTCACTCTGGACAATCTGGCCCCACTCCC CAGCACCTGCCCCATCTCCTGCTACTGCCCTCACCAGCACAACACTCCCACTATACCCTC CAACCTGCAGTTCCTCCAGAAACACATGCTTTTTTTGTTTTTTAAGAAATGTAGGCCGGG CGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGACCCAGGCAGGCGGATCAAGAG GTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCGTCTCAACTAAAAACACAA AGATTAGCTGGGCGTGGTGGCGTGCACCTGTAGTCCCAACTACTCATGAGGCTGAGGCAG GAGAATCTCCTGAACTCGGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCCACCACACT CCAGCCTGGCGACAGAGAGAGACTCCATCTAAAAAACATATATGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTATGTGTGTATATACATGTACACATAGATATGCGTGTATATACATGTA CACATAGATATGCGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACA TAGATATGCGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACATAGA TATGCGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACATAGATATG CGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACATAGATATGCGTG TATATACATGTACACAGATATGTGTGTATATACATGTACACATAGATATGTGTGTATATA CACACATATATACATCTATACGCACACATATATACATATATATACACACACATATATACA TATATACACACACACATATATATACACATACACACACACACACATATATATATATATATA AACTTGGCCAGGCATGGTGGCTCATGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGCAG GTGGATCACTTGAAGCCAGGAATTCGAGACCAGCCTGGCCAACCTGGTGAAACCTCAACT CTACTAAAAAATACAAAAATTGGCCAGGTGTGGTGGCGCACACCTGTAATCCCATCTACT TGGGAGGCTGAGGCACAAGAATCACTTGAACCTGGGAGGTGGAGGCTGCAGTGAGCCGAG ATCACCCACTGCACTCCAGCCTGGGCAACAGAGCGAGAGCGAGAAAGAAAGAAATACAGA AAGAAAGAAGGAAAGAAATAAAGGTATTAACTCAAAAAAAATTTTTGTTTAAATGTACCT CCCATACTTTTTGGCCCATTTAATTTTTTATTATGGTAGAATATACAACAAAAATGTATC ATCTTTAACCATTTCTAAGTGTGTCATTCAGTGACATCAATTATATTCACAATGTTGTAC AGCCATCTCTGCTATCTCTAAAACACACTATTTTTCGTGTGTCTTTGCACATATTATTTT CTCTGCCTGAAACCCCATCCCTATTTCCAGGTCCCATTAGCTTAAATAAGTCAAAAGTGT CTCCTACTCTTGGGGGATCTCCCCTGGACCCCGTGACCTTGGCTGAGAAACAGTTCTTGG CTCTGGGAATAAGAACCTACGGTCCAGTCTATTGTATAGAATACAGACTGCAGCTGGGCA ATACTTGGCCTTCATGCTCCAATCCTGTGTCTTTAGCCTTAGCAGGATCTCTGATGCACA GTGTCTGGCACACAGCAGATGCGTGTCAACACTGTGGATAAATGGATTATAGGAAGTTAT ACAGTCAAGTTAGAAGGAAAGATAAGAACCCAGTCTCCCTTCATTCTCTCTCCTTTTATC TCGAGCTTTTTATTTTATATATTGCATTCTCACTTCACTGTTTTTACCTAGAAAGGTTTT TCTATTTAAAGCAGATGTGAAATGTCACTTTCCTAAAGAAATATGACTTCCATCTCATAC ATAATCTGTCCAAAGATTGTCACTTTTGGGGGCAGGTCACCTACCTTCATATTACAGGAA AACAGTGTGCAGTCAAAAGTACCATGGTTACATAGGTGGGACAAAAATGATATCACAGAA AGAATATGTCAGCTGCCCCCAAAAAAATTCAACTAGGAGGGAAAAAGATGCCAAAATGGA GTCTAAGATATCTGCTATTTAGCCTGAATGTTAACACTGCCTACCCAAGAAAGAATCTGT TAACATATATTTGAGCCCTGGAAGCGTCTCTGGAAAATAAAGCTGCACAGGCCTTTCCTA CACAAGTCTTCAAAGCAGGACCAATAACTTTAAGACCGGAGTCGCGGTAAGAAACTTCAG TATCTATGACTGTTTTATTTAAGCACAAACAAGAGGAAATATGCATCCCCCTTTTTAAAC CTAGAGGCATAAAAAGAGATTTAAACATATAATTCAAAGTATCTTTAGTGGTAACATCCA GAAAGATCACAGGATGTTTTTTCCCCATGTTAAGTCTGTGCCTGGGGCTCCCATTCTCTG TGCCTTGTTGTTTCTGGATGTAATAAAATCCCAGAAGTGGGAGGAATATTTGCAAGTCCC CACACCACAATGGTTGTCTTCGGGAGACCCAAAAGATTAAGCATCCAGTTAAGGCAGCGC TTCTCAGGCACGGCACCACGGGCGTCATGCGGTGGATGACTGTGGCAGGGACTGCCCTGG GCATCTTCCTGTGTAGCATCTCAGGCCCACTCACCAGATGTCAGTAGCAGCCCCACACCC ACACCCAGTTGTAACAACCAAAAGAGTATCTACAAACATGGTCAAATGCCCACAGTGGGG CAAAACTGTGGTTGAGAACCACTGACTTAAGGCGAGGGAGCATCTAAGAGGATGCTGTCT GCCACTGAGTGCCTTCAGAAGAGAGGGATGCAGCAGCTCAGGCCGTGACAACTTTAGATT CTTAAGGCTGGAATTTTCCCATGTGTGCCCATGGCAAGAACAGTAAAACCTTAGGGGGAA AACGAGTTGGGTAATTGTAGTCAAGGTAGCAGGGAAGAAAAAAACTGAGAAAACTTGATC CACTCCATTTAAGGGAAGACCCAAGCTCCTCACAAGCGTAAGGGGACAATGTCTGGGTTA TTTTTTATTTTTTTTTATTTTTTGAGATGGAGTCTTGGTCTGTCACCAGGCTGGAGTGCA GTGGCGCGATCTTGGCTCACTACAATCTCTGCCTCCCAAGTTCAAGCAATTCTCCTGCCT CAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCATACCTGGCTAATTTTTCGTA TTTTAGTAGAGACAGGGTTCACCATGTTGGCCAGGATGGTCTCAATCTCCTGACCTCATG ATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTGGC CAATGTCTGGGTTATTAAAGAGTAAAGGAAACAGAGCAGGAGGGGAGGGGCTGCACTAAG ACAAAAAGGGAAAGGAGCGCTTGGGAGCCACATCGGGTGCAAAGTGCTCCTGGGACTCAG CTCTGAAAGCAGGACCCTGAACAGTGGTCAATGTCCCCACCCAAGACAGAAGGTTACCTC CCAAAGCTTCACTTCACAGAAAGAGTGGACAAAGAAGAAACGATCCTCAAGGTAAAACAC AGTATTTTCAAATGCTTTACTTGGTCCTTCCAGGTATTTCTAAATGGACCCTTAAATCTC TTTCATTTTTTTTTAAAAGAAAAAATCTTCAGTCAATTACTTCAGAGCCATCTCCTCTCC CCACTGCTCTGCTCCCCTGCCCCAAAATTGAGTATAAAACTAGTAACTGGGACATTCCAG AAAAGAGTGACAAAGGTCAGCCATGCAGAAATCTCAGAATCCCCAGAGAGGAAGTCTCTT CCATCCTTAAATTTCCTCTCTAGGAATAAGGAAATTCTACATCTCTTCAATTTGACTCCA GTTTTTATTTTGTAAACCACAGCCATGTTTGCTATTTAAGACTGATGCAATCATGAAAAA CTTTTAAGAAGTGGTAACCACTTCTCTAAAAAGAAGTGAGAATGACACAGAGTGAAAATC AAAAAGGGTAAAACAGAATGAAAAGAACTATGAGCTAAGGAATTTCAGTTTGATTTTTCA GTCTTTCTAGAGTATCAAATATGATCGTGTTAAACTAAAATGTCAGATTTTTCCATTGCT CATAATTCCTTAAGTCAATAGAAATAACCAAAGGTGCCATAAGCCAAGTCTGCATCTTCC TGTACATTAGAAAATTCTCCCCAGCAATCCCATTACTGGGTATACACCCAAAGGAATATA AACCATTCTATCACAAAGACACATGCATGCGTAAGTTCATTGTAGCACTATTCACAATAG CAAAGGGTGGAATCAACCTAAATGCCCATCAATGATAGACTGAATAAAGAAAATGTGGTA CATATATGCCATGGAACACTATGCAGCCATAAAAAAGAACAAGATCCTATCCTTTGCAAG AACATGGATGAGCTGGAGGCCATTATCCTTAGCAAACTAACACAGGAACAGAAAACCAAA CAGGGCACCTTGTCACTTATAAGTGGGGGCAAAATGATGAGAACACATGGACACAAAGAG GGGAACAAATGACACTGGGGCCTACCAGAGGGTGGAGGGTGGGAGGAGGAAGAGGAGCAA AAAAAGGGAAAAAAAATCACTACTGTGTATCAGGTTTAGTATCTGGATGATGAAAGAATC TGTACATCAAACCCCTATGACACATGTTTACCCATATAAGAAGCCTGTACATGCACCCCT GAACCTCAAATAAAAGGGTTTTTTGTTTGTTTGTTTTGAGATGGAGTCTCATTCTGTCAC CCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAATCCCCTCCTGGGCTCAAGTA ATCCTCCTACCTCAGCCTCCCAAGTAGCTGGGACCACAGACGTGTGCCACCATGCCCGAT TAATTCTTTTACTTTTGGTAGAGATGGGGTTTCACCATGATGGCTGGTCACAAACTCATG AGCTCAAGTGATCTGCCCGCCTCAGACTCCCAAAGTGCTGGGATTACAGGCATGATCCAC TGCGCCCAGCCAAAAGTTTTTTTTAAAAAAGAAAATTCTGGCCCGGCCCAGTGGCTCACG CCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGTCAGGAGTTCAAG ACCAGCCTCGCCAATATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCACGAT GTGGTGACGCGCACCTATAGTCCCAGGTATTTGGGAGGCTGAGGCAGAAGAATCGCTTAA ACCCGGGAAGCAGAGGTTGCAGTGAGCCAAGGTTGCACCACTGCACTCCAGCCTGGGCGA CAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAATTCTTAAGAGGAAGATAGGTGCT ATGTAAATAACATTTGGGATATTATCCTTAAGGGTGTTCACAGAATGGAAGAGATAATGC AACAAAAGACCCCAGCTGTGAGACCCTGGTCCTCATAATGTTCAGCCCAAAGATGGAATA GAATGTTGAGATCCAAGTGGCGTATAAAGTATCAACAAATTATTCCCACGGTAAAACACT TGACCAAAGGAGAACTTAAGCCTTGAATAGTTAATCTGTTCTATAATATCCATTACCAGA GAGGCTGAGATGTTGCGGTCTAAAAAAAACAAAAAACCAAACCACTAGCTTAAGAATTAA GAGATGAGTGCTAGTCCTATCTTAGCCTAACTAAACTTTGTGAGTTGAGAACATCACATA TGTCTCTCAGCCTCAATCTTCACATCCGTAAAATGAACTGGAGTGTGAACGACTCCTTAC CAGTGTCATTCATTCATTCATGCATTCCACAAAGTTTTTGAGCCATATAATGTCAAGCAC TATTCTTGGTGCTTGGGGAAACAGAGGTGAACTAAAAAGACAAACAAAGCTTATGTTCCA GATTCTGAAACTATTATAAATTGGTGTTTTCACACTATGGGTTGTAAAATCCAGTTAGCA GAACCAGATGAGCACTTTAAAAGAAGAAATGGCATCAAATAGTATAAAATGTCAGAGTAC ATCACATATAGTAAGGAGAAGTTCTGGTTCATAAAATTTTGCTTCAGTTATTGATAGATT CTTATATTTGTGAGGATTGCAGGTAAGGAGGTATAAGGCATTTCTGAATATGGGTTGGTT GTGTCAAAGGAGTTTAAAACTCCCTAATAAAAGGCTTCATTTTGTTTCAGCCACTGTCCT CATCCTAACCTTCGCTTTAATTACTTCTTAGGAACATCCTGCCCATAGATAAAATCTCAT TACTTTCCCGTTTGCCCCATGATGGCATTTTGGATAAATATCAGAGATATTTTTCACTCT TTTCAAATCAGTATTCCCAACCTCTCTGGGTAGGATTCCTTTTTATATCAGTCCTTCTTG TCTGTATTACTTGTCTGGTGATTAAGAAAATACATAGTGGCCAAAAGCCACAAGAACTTT TAATGGATTCATAATGTATTGGTCCTAAAAGCTTCTACGTAGAAATACAAAGAGTGCAAA CACACGGAGGACACATTATTCATTCCATCGACCAACCATGTTTGATGTTCAGACAGGTGT GCAGACTTCTTATGCCCTGAGGGGTCATGGGCACAGAGATGAGTAATCACTCTTCCAGGC CCCCACTTTTATTTGGCCATTTTAAAATCACTGTGTTCTTACAGATGACTGCTGAGGGTG GTTTCTGCTTGTTTTAATGCTTGTTCACCCTCTTTTCTTTCAATTAATGCAAACTACTAA ACCTAGCTACATGAGTTTGTTTTTCATTACTGTTATTCATTTGCTTTTTAATAATTTTTT AAATCTCACAACCCCAGGTTCCTTCGAACAGCTAACAGGAATTGTGAAGATAATCTTTCA GAATCTGCCTAGAGGTACACCCAACCCTACAACTGCCCTGGTTTTGACAGAAAACATCCC AAGGCAGCCATGACCATAACTTGGAAAATGAAAGGAGGTGAAACCAAGAGACAAGAAGGG TAGAAGGGAACTAAAAGAAGCAAGCAGTGTCAATCTTCCTGGGAATCTGGATGCTTGCAC ACCGATCAAGGTCCACCTGAAGTCACAAAACCACAGCCCCAGCTTCTCAAAGGTTCCCTC CCTCCCCCGCAAGTCACTTGAGTTTCAGTCCATTATCAAGCTCTAGCTTCCCCATTCTGT GTGGCCCCTATTAAATTATACATAAAATTTATAAGTTAGAAGGGGGCTGGGCAAAGGGGG AGCCCAGGCCCCTTTATTACAGAGGTCTGAGGGGGGCCACTTGGGCAAGGCAAGGTCAGC ACTGGAGAAAGTTTCCTGGCAATCAGAATCCCCCAGCAGACATCAAGCTGCTGCCTCCTG CCCCCAACTTCTACAGACCAGCTCTACCCCTTCTCTGTTATATTCAACATTTTCCTGTTC CTGGAAATCCCAGCCACTTTTGGGGAAAGATGGCTACCAGGTGCAACCAAGAGAGGAATG CTGCTTCACACATCCCTACTGTCGGCAAATACACAAACCTAAAATACTTAAAACTAAGTT TCATGCTGTCACCTTTACCATGTTTTTTTCTAGGTTACCCATTTTTTCAGCTTAAAATGA ACAAAATGTGACCTGTTCTTCATTAATAAGGAAAAAATTAACTTCTGGAAAAACCTGATT GCTTATTTGGCAAATTACAGAGAAGGTCATTTAACCAGTTCCCAGCATTGGCTATGAGAT GAGGGACCCAGCCGGGAGGATGGCTAAGCTGCTTCTGGCTTTCTGCTGCCTTGTGCCAAT AAAGGAAGGGCCTCCCTGATGGTGCTCCTGGCCTTCAAAGCAATCTCATACTGGTAAGTA TGAAGGAATAACTGCTTCTAAAGGTACAGCAATTTCTAGTTTTTCTTTAAAAAAAAAAAA ATCTCTTGCCTAGCAATTTCTGTAAGTTGCTCTCAATATTCCATAACAAAACCCAGGACA GTCATTAGCAAGACCTTGAACTGAGTCAGTGCTTAACCATCATTTTACTAAAGAGAAAAA TCGGGAAAGTTGTCGTAAATTACCTAAGCAACTAGAAACCAAGGACTTCAGATTCCTCCT TTTTTGTTATTTACCAGCTCAACAAACTCAAAGTGAGCTTGGAATATCTATCAATGGAGA AGTCTAGTGATCGCATAAATAGTACTAACTTTAAAATCTAACTTCTAAGTATACACATAT TCTAAATATTTAATGAGCCATCTATCTCTGTACTTTGAATCTAGAATAGCTTATTAGCTA GTTACAACCCAACACCACCCTGGTACATCTTTACACTAACAATTTTAAAGCCAGGCAAAC CCCAAGTTATGTCTAGGTTTTATTCCAAGCAAACTTAACTTTACAAAATTAGTAGTTACC AAATTTCTGAAGAGTAGGTGATCCGGGTGGAGATGAATTTCCACTAGGAGACAAGTAGAG ATAGCTTTTGTTCACTCCTGCATCAAAATCAAACGGGGACTGGTAGTCCTCATATAAGTC CATCTCTCTACAATCCATTCCAGACAAACGCAGAATGCATGGCTGTCTAATCGCCTGATA TCAGCCTTCAGTTGAGTGCCGCTTTGGCCATATTCCCTTTGTAGGGTGCAACTTCACTGA AGAAATCAACCCCAGGAGTTAGAGGCCCTGGCTTCTGGGCCCAGGTGCCAGCATTTCCTT TTGGGAGCCTTCACGCCCCTCCTGATAAGCAGACCTATTTAATAAATGATTTATCCTGAG CAACCTTAGGAGGGGCTCTATTCACCACCTGGTGTTAATTTCGATCAACAATGAAAAACC TGGGCAGGGAGCGAGCTTTCCTCAGTCAACAAAGAAGGGCAGGGTTCTGCAATATGGCCC AGAGGTACAAACAGTTCAGGCAAACATCAGACACTGGCTGACTTACAACAAGAAACTACA ATTTATTTAAAATAAATAAATAAAAAAATCAGCTGACCATGACTACACCAGGGCAGACTT AATCTTCTAGGACAAGGAGGGATTACCAGTCAGTAATCTCCCACAAATGCCATCTGAGTG ATACTTTTTTTCCACCCTGGATTACAGTAAAATTCTGAAAGCCAAGCTTCCTGGTTTAGC AATCAGCTTTCTAAGCACAACTTGGTATAAAAATAAAGCTGTATTTCCATGATTACTTTA TCTAATGTGGAGTCTGGCTGAGTGTCACAAAAACTTCAGACTGACTTTTCTTTTCTCTCT CTTTTTTTTTTTTTTTTTTTTTTTAGAAAGCTGGTGCTTCAGTTACATGCACTCAAAGGA GAAGAATCTACTTTGAATGGAAAGCTCCCGGGTATTCCCACACCTTCTTTGTTTGTCTAA GGCCATGGCTCTGCAGAGCTGCAATAAACCTGCGTACCCACCCTGCAGAAGGACTGGGCC ACAGCTAGCTTGTAAAACAAAACTAAGTCACCAAATTTATTTCCTTTAACACAGTCTCTT AGCAGAACCTTTCTATGCTGACTGTGGCCTTGGCTCAAGCAACAGCAATTGCAGCTCCTG CTGGTTCTACTAAGGAGGTAAAAATAAAGGCGACTCGCTTTCAGGTGGGCAATGATCTGT TACTGCATAACAAAAAAAAAGGCAGTGTTCTAATCTAATCTAAAAGGCGGTTTTCAAATC TAAAAAAAAAGAGCTCAGATATACTCTCCTTGGATTGGAAGCAAGTATGAAACCTAATAT ATTTTAAGCATTAAAAACATCAGCATGTGTCTAGTGTATAAAATACATATGCACCAAGAT GGTCTGTATTCATCTTGTGATTTTTTTTTTTTAAATACAGAATATATGCTGGATGATTTT ATTTGTTATTTTTGTTAGTCTCATGTTGTACTCTATTTACAGTAGGTCTTTTTTTGTTTT GTTTTCGATACAGAGCTTCGCTCTTGTGACCAGGCTGGAGTACAATGGCACAATCTCAGC TCACTGCAACCTCCACCTTCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGC TGGGATTACAGGCACCCACCACCCACTATGCCCGGCTAATTTTTGTATTTTTAGTAGAGA TGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCTG CCTCGGCCTCCCAAAGTTCTCGGATTACAGGTGTGAGCCACCGTGCCCGGACTATGGTAA GTCTTTTTTTTTTTTTTTTAAGTTTATTTTTAACAACAAAAAAATCTGTATTTTTCTCCT AAAAGGTACCAAAATTTGGGCAACTATAAATGTTTCATTCTATACTTAGAAATAAAATAA ATGGTTTCTTTTTTATCATTATCTGAAAGAATGGATTGTCTGGCTTCTTGAAATCCATGG CCTCTTACTGGGACAGGAAAGGCATTGGAGTTATGTCCCTAGACTAGAAAGAGTATGGTT CATGAGGTCCCTGGCCCTCTCCATAACTCTGCATTTGGTCACTAAATATTGGTAGAAAAA GTATTTGTCCATTACTTTACTTGTTCCACCACCTAGAGCCAAAGGCATTAGAAGGTAATT AATAGTGATACGGATAGAATGCAAGCCACAGTCACCTCCATCCTTCTCACCATCTCTCAA GCCCATGTCCTTGACCTTTGGTATTTACATCCATGTGACACGCTCTACCTGAAATGTCAC CTTTTTCCAGCCTGTCAAAGTTATTCATCCTTCAACACTGAGGCAGAAATGCCACCTCTT CTTAGAAGCCCCCTAGTCTCTGGCCCCCTCTTCTCCCAGCAGCAGCACACAGCATGTGAA GAGCCCCCTGACAGGCGCCTGTGCCTATCCAGGGCCTCTCCAGGGCGCTCTACCGGATAC CTGCCCTGAAGGTTTGGCTCCTAATCAATGTGGAATTAAAAAAGCAAATGATGGCTCATG TAGATGTTACATGCCTTATTAATAAATGTGAGCATTTCAAATTTAAGTAATTGCCTAAAA TTTTTATTTTACCTGCTTAGATACAATCTTAGGACTTTTATGCAACATCCTGGCTCTTTG AACCAGTTTTTGTTCTCATTATCTCCAGTCAGATCCCAGTCAAGACATTCTAGCCTACAA GAAAAGTGAAATCTAGAAGTGGGAAAAGCATGGGATGGGTTAATGGAATGGCAAAAATTC AGTTAACTCAACAGCCAAATACAAAGTAGAAAGGAACTGAAAGACATACAAAATGGAAAT GTAGCTTGGGGGCAGACCATTAAAGACTTTAACAAATTTTATACTTAATATACTGTGCAA AAAAAAAAACAGGATTTATGAGTCATACGGAGAGTATAAGTTTTATAAAGATGACTCTAG AAATGGTATAAGGATGCACTGCAGGCATAAAGAGGCTAAAAGAGAGAGGACTCAGAAAGA GGCTATGGGTACAATCCCAGCAAGGAGGAGAAAGCCTTGTGATATGGTTTGGCTCTGTGT CCCCACCCAAATCTCACCTTAAATTGTAATAACACCCACATGTCAAGGGCGGGACCAGGT GGAGTAAACTGAATCATGGGGGCGGTTCCCCCATGCTCTTCTCCTGATAGTGAATGAGAT AGTTCTCTGACGGTTTTATTAAGAGATCTTTATAAGGAGAACAGATGGTTTTATAAGGAG CTTCTCCCTTCGCTGGGCACTCATTCTCTCTCCCGCCACCCTGTGAAGTGGTGCCTTCTG CCATGATTGTAAGTTTCCTGAAGCCTCCCCAGCCATCTAGAACTGTGAGTCAATTAAACC TTTTCCCTTTATAAATTACCCAGTCTCAGGTATTTCCCCATAGCAGTGTGAGAATGGACT AGTACACCTTGGTATCGGGGCAACTCTTTTTATTTCCTGTTGTGGACTAGTCGGCCTGGG GAAGAACCAGGTAAGATTTGGTCCTGTCCTGTGGATAATTCCACTTGGCTCTTCCAAAAG TACTTCAAAGTCAGCATGCACAAGACTGAATTCACTGGCTTTCCTCACAATGTTCTTACC TCTAGATTAGGCATCCTGAGTCTCCTAGACCTGACTTTGAAGGAATCACATCCAAGCACT CTCACTCCATATGGAGAAAGCACGAAGAGCTATCTACCAACCGGTACCACAGGCCTTCTA ACCTTTCCTTCATTTCCATTGTCCTCATCCACACCCTACTTGAGACCCAGGTGGAGGGTG AGACCCACTCTATTGTTACTATGTTTTTCCTTCTGGGAGGGACCAGGCCCCACAGCAGTA TGGTAGACATCTGCTATCTTGTCAATTTTGCCCCTCTTCCCCTAGAGGAATTTCACCTCA CCTGCTCCCTGGGGTTCTCAGTGGGGAGAGAGGTCCATAGTTCCCACCCCCTGGCCCCAG GCATGGGCCTGTGCTTCAGATCTGGTCCACGCAGACACCCCATCCCCTTGTTCACAGGGA CTGGCCTAAGGATAGACATCTGACCCAGACACTGTCAATCAATCAGTGGCCTTCCTTGAT GTTTACTCTGTGAGTAATGGAAGAAAGTGACTCTCTCTGTAACCTGAGCTGTTGGGTGGG GCTGGCAGCTCCTTCCCTCACCAGGCCAATGGGCAAGAGACTCAGTGCTGAGACTGGGAA GGGACAGAAGGAGAAACAGAAACAGACAGGTAAGGGATGGCGCAGCAGCATCTAAGCCCC TGCCTCCAGCTACCCTGGGCTTCCCAGTTATTAAACAAACACAATTTTGTTCTGCTCCAC TTGTGGCTGGAGTTGAATTTCATCATTTCAGTAGAAAGAGTCCTAACATACCTACTTTCT GACCATATTTCCCACTATTACTCAACCATGCTTTAGCCAAACTTGACTTTCCTGTTTGTT GAACACATCCTAAACTTAGCCCAGACAATTTTCTCAAACTAGAGTTTCCCCTTTTCCTGT AAGTTCCTACCCATTTAGCAAGCTCTACTTATTAAGTCACATATGAATAGTATACATGCA AGGGACATTCACTTTAGATGCTACCTGAAATGGAAAAAAGCAATACAAATGCCTACTAAA AATGGATTATTTAAATGCTAAAAAGAACATTCAGGTAATAGAAAAATATGGAAACACTGA CATAATTATATAAAAATATTTATGAATTTTATATGGAAAGGTACTGATACAGTTAGCAAA CAAATCAGGTTTGAAAGAAGGTTGTATTGTATGGTCCATGTTTGTGTAATAATTTATGAG AGAGAAAACCACAAACCAAAAGAAAGAAAATGGGCAGAAAGAGAAATCCATTCCATGACC CCAGAAAAGTGCTCACGCACCACTATGCCAGCAGAGGGAGCCCAAGGGCAGTTCAGAAGT CAACTAGGTGCAGCCAGTAAAGTGCGTATGTACTGCAGGGTAATAACCGGAGACGACTCA TGTCATTGCAAACGGAAATGGTAGTAGGTACAAATGACTATAAAGAAAATTAAGTTTCTG TCTGCCTGTTAACTCATCACTCAAATATGTCAGTGTAAATTCTCCACAAACTTGAAAGAC ATATAAAGGACAGTCTGATTTAAAAGCTATGAAACACAATATTTACTTGGAGGGCACGTC AAAGGGAGACAATGTGGCTGTCCACCAGGAGAGGCAGGCCGCAGATACTTGGGGAATGCA GACGTGTCATGGTGATACAGCAGCTGGCTGGAAGGGGCTCCAACTAGCCAATATGGGACA ATCAGGCCGCCAAAAAAATTAGGGACAGTCAGGGATTATAAACCACTGAAAAAAACAGGA ATCCAAGAGTCCAAGAAAGTAATAAATAGAGAGAAGGAAGAACTACAGAAGAATGCCACC CTGACCATCTTTGTAAAGATTCAGACAAAAATCATCGCTGGATGCTAAAGCTCGGGAGAA ATTTTGAGGAAGAAGATGATATTTAAATGATGTTTAAAGTGCCTCTCCACAGATTAACTA GCTGCCAGAAGGAAAAACATTGAGTGGAGATCACTTCTTGGCCTTTTGGCTGAGATCAAG TGTAGTAACAGTATAATGGAGAAAAGCCCCACCCTGACTGAAGGATAGAGATGGCCATAC CCCAGTGAGAGGCAGATGGACCGCTCTGAATACCTACATAGTGTTCAGGCTTGGAATGCA GAACCTGAATCGAATCATGAGGAAACATCAGACAAATCCAAAACAAGTTTTTGTTGGGGT TTTGTTGTTGCTTCGGGTTTTTTTGCTTTTTTTTTTTTTTAGTTTTTTTTTTTTTTTTTT TGAGACGGACTCTCACTCTGTTGCCAGGCTGGAGTGCAGTGTCGTGATCTTGACTCACCA CAACCTCCGCCTCCCCGGTTTAAGTGATTCTCCTAACCTCAGTCTCCTGAGTAGCTGGGA CTACAAGCGCACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTC ACCATATTGGCTAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCGGTCCCC CAAGGTGCTGGGATTACAGGTGTGAGCCACCGAGCCTGACCGGAAGGTTCTAGTTTTTAA AAGAGGAGGGGCTGCATTCTTCAAAAACATCGATGTCATAAAGGACAAAGACTGTGAAAA TCCACATTAAAGGAGACTGGCATTACTAGGTCCATTGAAAAAACTGGAATATGACCTCAG ATTAGATAAAAGTCTTGTATCAATTTCAAATTTACTGGCTGGGCTTGGTGGCTCACACCT GTAATCCTGGCACTTTGGGAGACCAAGGCAGGCAGATCACCTGACATCAAGAGTTCGAGA CCAGCCTGGCCAATATGGTGAATCCCCGTCTCTACTAAAAATACAAAAATTAGCTGGTTG GGGGGGCACGTGCCTGCAGTCCCAGTTACTCAGAAGACTGAGGCACAAGAATTGCTTGAA CCCGGGAAGCGGAGATTGCAGTGAGCTGAGATCGTGCCACTGCATCCCAGCCTGGGCAAC AAGAGTGAGACGCTGTCTCAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCAAAT TTACTGACGTTGACAACTGTGGTGAGAATATTGCCTTTCTTAGGCAATGGCAATATATAC TGAAGTATTTAGGGGCAGACGCCATGATATATGCAACTTCCTCTCAAATTGCTCAGAAAA TAAGAGTATGCATGTGTACAGACATCCACACACAGAGAGACTGGTCAACCGGATGGGGCT AAACGTTAACAGTGACCCTGAGTAGAGAATGCAGGTGTCCTTTTTTTTTCCCCCCATCAA CTTTTAAGTTCCAGGGTACATGTGCAGGATGTGCAGGCTTGTAACATAAGTAAGTGTGTG CCATAGTGGTTTGCTGCACAAATCAACCTATCACCTAGGTCTTAAGCCCAGCATTCATTA GCTATTCTTCCTTATGCTCTCCCTCCCCCACACCTGTGTTGTTGGCACATATACACCATG GAATACTATGCAGTCATAAAAAGGAACAAGAGCATGTCCTTTGCAGGGACATGGATGGAG CTGGAAGCCATTATCTTCAGCAAAGTAACACAGGAGCAGGTATTTACACTATTCTTATTC TTGCAATCCTTCTGTAAATTTGAAAAGGGCTAAAAAACAAACAAACAAAAAACAAGAACT CCTCTGCCTTAGATTCAGCAGCCCTGAGGGCGCTGTGGAGAAAGTGTGTGGCAACCACCT CTCACAGCAATCACGGGGGCAGGGCCTAATGGGACTGGGCTCCAGCCACAGACACACAGG CACATACCGGCTCCAGGCCCCTTCTGAGAGCTGGAAGGGCTCTCTCCACCTTCCACCGAA GCAGCAGTTGGTTTACCTTCTACAGAAAAGAAGTCTCCCCATCATATCCCATGCTGGTCA CATCTTCCCAGAGGGAGACCAGTGGGGACCCTGTTGCACAGGGTGAGAGGGCAGAGAGGC TGAGAGGTTAATGAACACCCCACACCCCACACCTCTTCATTCCCCGACACTGTGCCACAA TAAACAAACCTTGACTCCAAATAAAAAGTACTTGATTTTAAGTATGAAATTCAATTTAAA ATCACAAGGGTAGATGCTCTCTTATTTACAAAATTTCTCAGCTAATCCTCAAAACCTCTG TGAGGTAAACCTCTGCCTCTCCCTATTTTTCAGAGGGGAAACAAGACAAGGACAGTTCCT GTAAACCTGTCTTTGGGCATAGAGCTAGCAAGTAAAGGAGCCGCAGTTTGAAGCCTGGTA CGTGCCTCCAAGTCCCTGTCCTCTCCATCCTGTGGCTGTAGCCTAGAGCCGGGCAGTAAG GATAAGCCAGTCCCTCACATCTAATGGCCCTGGGGATCTTGCTGTGATGCAGAGTCTGCA TCCTGGTGATGGGAGGCTGCTGGCCCTGGAACCACATGGGATCACACTTGGAGTAACAAG GTGATGGAAGAACTCGAATGGAGGCTGGAGAGTAGGAATTTGGTTTTCGTCAGATTAAAG CAACAATTCTTCATTAGAATTTATTTAATCCCTCAATAACACGAGGTTAGTCATGTTATC TCCAATTTCCAGAGGAGTGAGCATAAGGAACTGAGAAATGAAGGAAGCCACCCTACAGTG GTCATTTTCCTCTCACTGCATCTAGGCCGTGGGGAGCCAAGTCGAGTAATTAGGAATGGG AGGCCAAAGCCACGTGTCAGAAAGATCATTCTCACCCCTGTCTGAAGCTGGACTGCCGAG GGGAGAGGGAAGTCAGGACAGCTACCCAGCAACAGCGCCAAGGGTGTTCTGGACTGAATT GTGTCTCCCCAGCTTCATGTGTTGAAGCCCTAACTCCCAATATGGCTGTATTTGGAGATG GGGTCTTTAGGAGGTAATTAAGATTAAACAGGGTCATAGGGTGAGGCCCTAATCCAATAG GACTGCTGTCCTAGTAAGAAGAGACACTAGGGATGCTCACGCAAAAGGCCTTTTTCACAG AAAAAAGGCCAGGGAGGACATAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCAC TGCATTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCA AAGTGCTGGGATTACAGGCGTGAACCACTGCGCCTGGCAGCTCTCTGTCAACCAGGAAGC AAGCCCATGCCAGAAACCTATCTACCCTGCCACCAGCACCTTGATCTTGGACTTTCAGCC TCCAGAATCGTGAGAATATAAATTTCCATTGTTCAAACCACCTATTCTATGGTATTGTTA TTGCGGCCCAAACCAACTAATACAAAAGGCATGTGCCCTGCATGGAACAGAAGCGGGAAC AGCAAAGCAAAGACACACTGCATGACACCATGAACAGACAATCAACAGATGCTGGAGATC AACTGGAGGACTTGGGTGACGGGCAATGAGAAGCCAACGTGTGATACCCCAGCAGGAGTT GTAAAGGACAGTGACCGCATTAATGAAGATGGTGGCAAAAGAGAGGCAGGACTGAAGAAC AGAGAGAAGAGACTTTAGGTGATAAGAGAATGAGCTGCATTTTGGCAGATTTGGTTAATA GAGCTCACAAGACTTCTGGAGTAAATGGCCAGCCTGAGGTTAGAAATTAAACTTCTATCC TCAGGGAAAAAGTTAGGGGCTAAGATATAAAATGTGGGAAACCCAGAGATCGTCAAAAAA AAATTTGAAGAGAAGAGAGGCCCTATGAAAAGGAGTGGAAAAATTAGTGAACACCTACAA TCAGCATGCAGGCCAAAGAGCCTAAAAAGGGCAAGCAATGACCTTTAATGATGACAATAA TTATGACTTATCCTTAAGGAACCCTTACTATGTGCCAGACATTCTTCTATGCACTTGCAT CAATTTTATGGGGTAAGTTTTTCCCTACCCTTATCTTACAACAAAACTGAGACACATCAA AGTTAAGTGTCTTGCCCTAGGCACAGAGCTAGAAAGTGGTAAAACTTAGGATTCCAATTC CATTGCTCTCAAGAAGCAAAACATCTGGAAGAAAACCTTGAGTGACCAATGTCACAGGAA TCAAGGGAGGAGAGAAACTGGATAAGATCAAATGCTAAAGAGACGCAAGAAGAAGCCACA GGACTTGGGGTCTGGTGATCTCGCACTGAAGTTTTAGTGAGAGTGATGGTAGATGTCAGA TAAGCAGAAGTGGTAGGCAGTGGAGGAAAGGAAAGGGAAGAAGCGAATGAAAAGAAGTTT TAAAAAGTATTTTAGGCCAGGCATGGTGGTTCACACCTATAATCCCAGAACTCTGGGAGG CTGAGGCAGGAGGATAGCTTGAGGCCTGGAGTTCAAGGCCAGCATGGGCAACAAAGCGAG GCCCTGGCTCTACAAAAAAAATAAAAAATAAAAATTAGCCAGGCACAGTGGTGCACACCT GTAGTTCCAGTTACTCAGGAGGCTGGGTCAGAAGGGATCACTTCAGCCCAGGAGTTCAAG GCTAGAGTGAGCTACGATGGTGCCACCTCTTTAAAAAACAAATAAATAAAGTTTTCAAAT GTGTGTGTTTAAGAGCAAAGAAGACAATGCAGAAGAGGAAGCACAGTGGGGATGGGGAGG GGCGGGGCAGACCAGGGGCCAAGGAAGGTTCAGGGATGCTGTCCCTCACCCAGGGGCATT TCAGTTCCTAAACTGAATGAAACTAGATTAAATCATGTTGGCATTCTTTTAAAAATATGT GGCAGTTTTCAGATTAGAAACTTTGCATTAGAAACTTAGGAAATATTCCCTATGGGAATG CCACTTCTTTTCTCCTTTATTTTCCATCCCAATGGGGGAAAAAAGACTATTATAGCACAG TATTATAAGAAAGAAAAAAAAAAAAACTATCCTCTTTGGAGCCTCTTCTCTAGAATAAAA AGGCATAACCTAGCAGGCATATGCAAATTATTTGGAACTAAATGTAAATACTCTTAAGTG ATAAAATGGATTTGTATTTTTAAAGAAATCGTTTATTTGGCCCACTGACTTGCAAAGAAA TTCTCACTTGTTAGGAACCCCTAACAGTCTACTTAGAATATTCTTCTGCCCTCTCAAAAT AACTAAAATTGAGTTAATGTCAGCAGCCAGGACAGAAGGTTTTTGTTCTTCACACAGTGT TTCCTTCAAATACTGAAGAGCAAGAGTGACATATAATAAGCATAAGATGTCATTCCCTCT CTCAACCTATCTCCAAACATGTCGTCTGGATAAGCCTGTACCTGGGAAAGTCAGAATCTG TTGAGAAGTCTCAAGAATGCCTGAATTCTCTATCACAAGGAGTCACAGACTGGATTCTAA AATACACAAAAGAGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGC TGAGGCGGGCATCACAAGGTCAGGAGATCAAGACCATCTTGGCTAACACGGTGAAACCCC GTCTCTACTAAAATTACAAAAAAATTAGCTGGGCGTGGTGGCGGGCACCTGTAGTCCCAG CTACTTGGGAGGCTGAGGCAGGAGAATGGCCTGAACCCAAGAGGCGGAGCTTGCAGTGAG CCGAGATCGCGCCACTGCGCTCCAGCCTGGGCGACAGAGACTCCATCTCAAAAAAAAAAA AAAAAAATACACAAAAGAGCATTACTATTTTCACTTCGGTCATCTCAGTACATGGTCCTG CCACTGTCATTGTCAGATCATGAGAACACCAGAAAATAGTGGAAAGAGAGCTTGATATTT GTCATATACTTAATTAGATACAATAGACAGATTTTTTCATTTTAGAAATAGAGTTTGAGT TGAAATGTTATGGTCACTCCACATACTGATGGGTGATTCCATGATTACAGGCTCAGGTAA AAGATCTCCAGCCAGTGCTTCTCAAATAACTTTATTACATACCAGAGCCACCAGGGGAGC CTGTGGAACTACAGATTCTGAGTTAGAAAGTCTGGGGTGGAGCCCAAGACTCTTGCTTTC TGGACAAGCTCCAGGTGATTTCTGATGCTGCAAGTCTGGCTTTAGATAACAGCTGCTAAG TTTGCCTGAGGATGAAAGCTTGAGTAAACTCTGAATACTGATGTTACAGGACTCCAGCAC TTTCTAACTATATACATTTGAACATAAGAGACAGATTTTATAGCTAAAAAGGTTTGGCTT TTTGTATATATTTCTTATTGATACAAATATGTGTACATGTATATGGGGGCACAAATATGA TACTCTATCACATGCTTACACTGTGTAATGATCAAATTAGGGGTTTGGGGCATCTATCAC CTCGAGTATTCGTCATTTCTGTGTGTTGGCATTATTCCAAGTCCTCTTTTCTAGCTATTT TGAAATCTACAATACATTGTTGTTAACTATGGTCATCCTACACTGCTATCGAACATTAGA ACTTATTCCTTCTAAGGTATGTTTGTAACCATTAACTAACCTCGTTTTATCCTCCCCCCA CCCACTGACACATCTTCCCAGCACAGCCACTGTGAAAAACAGTATGGAGATTTCTCAAAA CAATTAAAAACAGAATTAACATATTAATAGATCCAGCAATCCTACTACTGGGTATTTGCC CAAATGTAAAGAAATCAGATGTCAAGGATATTTGCACGTGCGCGTTTATTGAAGCACTAT TCACAATAGCAATGATATGGAATCAACCTATATTCATTAATAGTTGAATAAAGAAAATTG TGGTATATATACACAATTTATTACTACTTGGCCATAAAAAAATGAATCTTGTCATTTGCA GCAACATGGGTGGAACTAGAGGTCATTATGTTAAGTGAAATAAGCTAGGAACAGAAATAC AACTGTCACACGTTCTCACTCAAGTGGAGCTAAAAACTGTAGATCTCGTGAAGAGAGAGT AAAATCACAAATTCCGTGTTATACACATTCTACCACAATTTAAAAAAAAAAAAAGATCAC ATAATTATAAGAGGTGAGATTGTCACTCACACTTTAAATTACTGCCAGAGGCTGGGAAGA GGAGGAGTTGAGCAGGGGTGGGGGTAGGAATAAAGGATGGAATAAAGGTGGAAGGGGGAA TAAAGAATATATTTATTACCAAGGAAGTGTACATTTCAAATGGTACAGATGGTAAATTAT ATACATATATTTTGTCTCAATTAAAAAATATAAAAACTATAAAAAATTAAATGTTAAAAA TAAAAGATTTTGTTTTTTGTTTTTCTGAGACCCTAACAGTTCACAAAGCAGGCAAGTTCA GATAGGACAAAACCGGCTGTGTCACAACAGGGTGTGCACATGCTTGGTCTTTTCAACGGG ATAATTATTTCGACTCTGGAATAATAATAATAATAATAAACAGAGTCCAGAATAATGGCT CAGTAATAAGAGAATGAAAGCAGGCCATTCTTACTAAAAGTATTAACAATGTATTTGAGA GTACAGTGGTCTCTATGGTGAGATTACTGGAAGATTAAAGAGGTGTCATCCAAGCTAAAT GTTTCCAATTTGCTGAATGAGTTTAAAGACAGCTCTACAGGGGTGCATAAACACAAGCGA CTGTCACAACCCTAAAAGGAATAAATGAACTGGTGGACTACATTTTAATGTGGAAAAAAC TTCCACAATGCTTACACAGCTATTCCTGGCAATGAGAGGCTCATATGAAACACTTTTCCT TAAGGGAATGGGAGTTTCTAGAGAACAGTAGGCACTTATTTAAAATTAATATTGGACCAC AAACTTCTATCATCAGCAAGCTGAGACCTAACAAACAAGATCAAAATACCAAGTCATACA TTTAGGCAGTTAAACTTGCTTTTAAACTGTAATAAGCTAATTAGATGCATTCAGTGGGTC AACCATTAAAAAAAATATACACTGCACAAATCTTGTCAATTTTTCATTAAATTTTATTAA GAAACAAGAGTCCTGTGCCAAAAGTGATAGCTTCACCATCTGAACCTGCTACTCTGGTTA AGAAATGACATTTCCAATTCCAAATTTCACATACTTTCCTTTATAAAGACAATAGCAGAA GACCAATGCTACATGTAAACTCAATAGTAGCCCATTATCTTGAAACCAAATCAGTGTGTG GAAAGCTTCAAAACTTTCTTTGCCTTTTGGCACAAGACTGAAGACATGAGATTTTTTTTA ACATCTGACCATAATAACTGCTGTATTAATCACTGTGAAGGCTCCTTGTTGACTTTTCTC AGAGTTTTATAAAACATCGCTATCAAACAGGTATTTATCAAAATAGGCATATAATTTTAT TTATTCCAGGAAGCTCTCTCAGTGTTAAAAGGATAAGATAATTAACGTTTAGATGGAAAG AGAGCATGGGATGGAAAAATGCTCTCCTGAAACACAGCCAGATCTATGAAACCATACAAT TACTGTCATGTCATCTCTGAAAGATCAAGTTAACAATGTGTATGATTTAATAATCTTACT TAATATGGCCAGGAATGCTAACAAATCGCCAAGCCAATTTGTTCTTATTCTTACGCAGGT AGCTAGACTACACCTCCCAGGCTCCTTTGCAGTTAGATGTGGCCATGTGACTAAGTTCTA GACAAAAGAAAATTTTATATATATATATATATATATATATATATATATATATATATATAT ATATATATATGTATGTATATATAACATGAGGGAGACATAAAGATTGTTGCCAATAGCCAC TGAGATTTTGGGAGTTACTGATGGAAACATATTGCCAAATATAGCTTCAGATGTATTTCT TCAAATTCCTCTTTTAAAATGATCATATCCCCAGGTAAGAGTTTTGGAAACAGATAGTGG TGATGGTTACACAATGATGTGAATATGATGAATACAACTGAACTGTATACTTAAAAATGG TTAAAATCACAAATTATATCTTATATACACATATTCTACCATAATTTAAAAAAAAAATGA TCACTTAATTATAAGAGTTGAAATAAGTTGGAACCATGATTAAGAAGTATTTTAAATACT CTTTCCTGAAAATATAAGCAAGACCTTTGTGTCCAGACTTGTTCAGAAAATGCTCTAAGT GAAGAAGAGGAAGCCCTGGGAGAGGCAGGCCTGGTTAGGTTGTCACAATAAGGAGGGTAA TTGTCAGCAGGAGGAGAGATGCTGGGACCAAGAATATATCACAGATCCTTCAATTGCACT CCCAGGTATTTACCCAAATGAGCTGAAAACTTATGACCACACAAAACCCTGTAGTGAATG GTCATAGTGGCTTTATTCATGATCACCAAAAACAAGAAACCACCAAGATGTCATTCAGTA GGTGAATGGATAATAAACTGTGGTACATCCAGACAGTGGAATATTATTCAGCACTAAAAA GAAATGAACTAGCAAGCTGTGAAAAAACACAAAGAAACTTTAAATGCATATTATTGACAA AAGCCAATCTGAAAAGCCAAAATACTGTAAGATCTCAACTATGTGACATTCTGGAAAAGA CAAAATTATGGAGACAGTAAAAAGATCAATGGTTACCAAGGGCTGAGGGGGAGGCAAGCA GGAATGACTAGGTTGGGGTGCTGGTGATTTTTAGGGCAGTGAAAGTATTCTGTATGATAC TGCAATGGTGGCTACATATTATGCATCTGTCAAAATCCATTGAACTGGACAACACTAATA AAAACTACAGACTTTAGTTAATAATAATGTCTCAGCATTAACCAAATGTAACAAATGTAC CATATGAATTTAAGGTGTTAATAATAAGGGAAACTAGGGGCGTGAAGGAACTCTGCACTA CTTGTTCAATTTTCTGTAAACCCAAAACTGCCCTAAAATACAAAGACTAGGCCGGGTGCG GTGGCTCATGCCTGTAATCCAAGCACTTGGGAGGCCAAGGTGGGAGGATCATGAGGTCAA AAGATCGAGACCATCCTGGCCAACATGGTGAAACTCCGTCTGTCTCCACTAAAAATACAA AAATTAGCTGAGTGTAGCGGCATGCGCCCGTGGTCCCAGCTACTCAGGAGGCTGAGGCAG GAGAATCGCTTGAACCCAGGAGGCGGAGGTTTCAGTGAGCTGAGATCGCGACACTGCACT CCAGCCTGGCAACAGAGTGAGACTCCATCTCTACATACATACATACATACATACTATCGG CCAGGCACAGTGGCTCACGCCTCCAAGCCCAACACTTTGGGAGGCCAAAGCAGGCATATT GCTTGAGCTCAGGAATTTGAGGCCAGCCTGGGTAACATGACAAAAACCCGTCTCTATGAA AAATACAAAAATTAGTTGGGCATGGTGGTGTGCACCTGCAGTCCCACCTGCTGAAGAGGT TGAAGTGGGAGGATTGTTTAAGCCCAGGTGGTCAAGGCTGCAGTGAGCCATGATTGTGCC AATGTACTCCAGCCTGAGTGACAAGAGCAAGAACTTGTCTCAAAATAAATAAAGACTATC AAACACACACACACAAACACACACACACACACACACACACACAAACTTCTCCTAGTCTGC CTGGGGTAAAATACTCAAGCACCAAAACTCATCTGCTTGGACTATGGTCAAGGCTTCCTA AGTATCTGAAGTAGCACCAAAGAAAGCATGTTTACATGTACAGGCATACTCCTGTTTTAC TGCACTCCACTTCATTGCACTTCACAGTATGTTTTTTACAAACTGAAGGTTTATGGCAAC ACTGTGTCCAGAAAGTCTATCTATTAGTGCCATTATTCCAGCAGCACATGCTCACTTTGT GTCTCTGCATCACATTTTGCTAATTCTCTCATTATTTCAAACTTTTTCATTATTATTATA TCTGTTATGGTCATCTGTGATCAGTGACCTTTGATGTTACTATTGTAATTGTTTTGGGAT GCCACAAACGACACCCATACAGGATGGCAAACTCAATCGATAAATGTTTGTGCTCTGACT GTTCCACAAACTGGCCATTCTCTCATCTCTCTCCCTCTCCTCAGGCCTCCCTATTTGATG AGACACAACAATATGGAAATTAGGCCAATTAATGTCCCTACGATGGCCTCTAGGTGTTCA AATGACAGGAAGAGTAGCACATCTTTCACTTTAAATCAAAAGCTAGAAATGATTAAGCTT AGCGAGAAAGGCATGTCAATAGTCTCTGTAGGCCAAAAACCAGACCGCCTGCACCTGCCA GGTTTTGAATGCAAAGAAAAAGTTCTTGAAGCTTCGAAATTACAAGTGCTACTCCAGTGA ACACATGAATGATAAGAGGGCAAAAACAGCCTTATTGCTGATATGGACAAAGTTTGAATG CTCTGGATAGAAGTTCAAACCAGCTCAACACTCCCTCAAGCCAAAGCCTAATCCAGGGCA AGGTCCTACCTCTCTTCAATTCTATGAAGGCTAAGAAAGGTGAGGAAGCTGCAGAAGAAG TCTGAAGCTAGCAGAGGTTGGTTCATGAGGATTAAGGAAAGAAGCCATCTCCATAACATA AATGTATAAGGTGAAGCAGCAAGTGCTGATAGGGAAGCTGCAGCAAACTATCCAAAAGAT CTAGCTAAGATAATTTATGAAGGTAGCTGATATGGTTTAGATCTGTGTTCCCATCCAAAT CTCATGTCAAATTGTAATCCCCAGTGTTGGAGGAGGGGCCTGCTGGGAGGTGATTAGATC ATAGGGGCAGATTTCTCCCTTGCTGTTCTCACAATAGTGAGTTCTCAAGAGATCTGATTG TTTAAAAGTGTGTAACACCTCCCCACTTTGCTCTCTTCCTCCTGTTCCACCCATCTAAGA CGTCCCTGCTTCCCCTTTGCCTTCCACCATGATTCTAAGTTTCCTGAGGCCTCCCCAGCC ATACTTCCTGTACGGTCTGTGAAACTGTGAGCCAATTAAACCTTTTCTTTATAAATTACC CAGTCTCAGGTAGCTCTTTACAGCAATGCAAGAACAAACTAAAACGGTAGCTACACTAAA CAACAGATTGTCTATGTAAATGAAACAGCCTTTTATTGGAAGAAAATGCCCTCTAGAACT TGCAAAGTTAGAGAGGAGAAGTCAATGCCTGGCTTCAATGCTTCAATGGACAGGCTGACT CTCTTCTTAGGAGCTAATGTAGCCAGTGACCTTAAGTTGAATCCAATGCTCATTATCATT TCAAAAGTTCTAAAGCCCTTAAGAATGATGCTAAATAAATCTACTCTGCCTGTGCTCTAG AAATGGAATAACAACGCCTGGATGACAGCCCATCTGTTTATAATATGGTTTACTGAATAT TTTCAGCCCACTGTTGAGAGCTACTGCTCAGATAAAGATTTCTTTTCCAAATATTACTGC TCATTTACAATGCACCTAGTCATCAAGAGCTCCGATGGAGATGTACAAGGAGATGAATGT TGTTTTCATGCCTGCTAATACAACATACATTCTGCATACCATGGATCAATGAGTAATTCC TATTTTCAAGTCTTATTATTTAAGAAATCCATTTTGTAAGGCTACTGTGGCCAATCTGCC AGAGATTGCTCGGGTGGGTCTGGGCAAAGTACATTAAAAACCTTCTGGAAAGGATTCACC ATTCTAGATGCCATTAAGAAAGTTCATGTTTCATGGGAGGAGGTTAAAACATAGCATAAC AGGAGTTTGGAAGAGGGTGATTCCAGCCTTCATGGATTACTCTGAGAGGCTTAAGACTTC AGTGGAGGAAATAACTGCAGATGTGGCAGAAATAGCAAGGGAACTATTACAGAATTACAA GTGGAGCCTGGATATGTGATTGAATAGCTGCAATCTCATGATAACACTTGAAGGGATAAG GAGTTGCTTCTTATAGATGAGCAAAGATGAAATCTACTCCTGGTGAAGATGCCGTAAACA CTGTTGAAATAACAACAAAGAATTTAGAATATTACATAAACTTAGTTGATAAAGCAGCAG CAGGGTTTGAGAGTTTTGACTCCAGTTTTGAAAGAAGTTCTACTGTGGGTAAAATGCTAT CAAACAGCATTGTATGCTACAGAGAAATTTTTTTGTGAAAGGAAGAGCCCATCAATTGCC ACGGCCAGCTCAACCTTCAGCAGCTACCTCCCTGATCAGTCAGCAGCCATTCTCATTGAG GCAAGACCCTCCAGCAACAAAAAACATTAGGACTCACTGAAGACTCACTGACCGTTAGCA TTTCTTGGCAATAAAGTATTTTTAAACTGAGGTAAGTGCACAATTTTGTTTTGTTTTGTT TTGTTTTGGGGGCGAGGGTATATACACAATTTTTTAGACATAATGCCTATTGTGCATTTA AAAGACTACAGTATAGTGTAAACATAACTCTTACATACACTGGGAAACCAAAAAATGTGT GTGAGTCGCTTTATTGCTATATTTGCTTTAATTATGGCTGTCTGGAATCAAACCCACAAT ATCTCCCAAGGTATTCCAGCAGTTCCAATGGAAAGGCTAAGCTCATAATAAAGGAAATAA CGGCCCTATTATAATATCAAATGCCATTATTAATGCAAAGTAGACAATCGCCTGACCAAC TGTAGCTAAATTCTTGGCATTTATGAAAAAACAAACAAACAAACAAAAAACACAATGTTT TGAATATCTGGCCAAGCTAGAGATGCTGCAAATGATGGGAGGGTATTACCATCTGCAAAG AACCTTCCACCACAGGTGAGGGAGGTTCACAAAACTGGATGGTGGTCTAACATCTTTTTT TTTTTTTTTTTTTGAGATGAAGTCTCGCTCTGTCACCCAGGCTGAAGTGCAGTGGTGTGA TCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCT GAGTAGCTGGGACTACAGGAGCGTGACACCACGCCCAGCTAATTTTTGTATTTTTAGTAG AGACGGGGTTTTACCATGTTGGCCAGGCTGGTCTTGAACACCTGACCTCAAGTGATCCAC CCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCAGCGCGCCCAGCTGGTCT AACATCTTTTTAAAATGAAACAGAAACAGATATCTATTGAATGCAGAAGTAGAACAAGTT TAAGGCCTACATTTAATTCTTAAAGTCTCTTTTCTTGGCAAATATTTGGTGAAAACAGCC TATCAAGATGACAAACCTATTATGGCCCAATGATACAACAAATACTGGCAGCCCTAGTTC CTTTCTGTGGATTTCTAAGAAGGCAGGCATGGGCCCCAGCATCTTCTCTAAGTAGTGTTC TAAACATTTAACCTGCATGTTTATCAAAACACGCAATTTTAAATTTAGATTCTTGATAAA GAGGATTTGATTTAGAAAGATAATCCTCTGGGGAAATCTCGCCTCCAAATTTTAAGAACT GAAAATCAAAGGGCACAAATTGCAGAAGGGGGCAAAGTGACACACAGAAACAAGCTCTGA AATAAACCAAAGTAATATCTTAGTGTGAAGATGATTGCTTTAAATAAGCTGATCCAAGCC CTAATTATTTTCTCTGGCAATTTCTTACTCTTAAACAAAAACAGAAACACTATTCATACT CCCCTTTACAGATTGTACTCTGCTGCTTATGAACAAGCAGACAAAGAGAAGCAAAAAGGC AACAGCACCTTCAGCATTTCTCTCTAAAAACCAATTGTTTTCGGAACAGAAACTAGAATC TGCCTCACTGAAAAACCCTACCTGAAACCAGGTTCATACTGGCTGCTGGATAAAGGACTT TTCAGCAGGTGGCATCTCAGAAATTACTTACTAAGTCAGCTCTTTCCAGTCACCTAGCTA GCCAAAGTTTATTAGGTCATTTGTACAGTCAGGGTTCTCATATCTCACAATTATGGAGGC TAAGTAAGAGGTCCCAAGACCTGCAGTTAGTAAGCTGGAGACCCAGAAGAAACTGTGGCA TTAGATTCTAGTTCAAGCCTGGGTCCAAAGGCAGGAGAAGACCAATGTCCCAGCTGGAAG ACAGTCAGAGAGAGGTTCCCTCTTTCCCAGCCATTTTGTTCCAATCAGGCCTTCAATGAT AGGATGAGGCCCATCCACATTCGGAGAAGTCAATCTGCTTTACTCAGTCTACCAATTCAA ATGTTGATTTCATCCAAAAACAGCCTCAGACACACCCAAAATATTTGACCAAATGTCTGG GCACCCCATGGCACAGTCAAGTCCACACATACATTTAACCGTTACATCATTCCTGAGCTC AGAGTGTTGCCATACCAAGTGTTACAGTGAGATATTTACTATTGAACGTATTAGCAGCAG GGACCCAGACAACAACATATTTAAAAGAGAAGAAAAGATGTATGGGAAGAGAAATAATGT AGATAACAGATAAACATAATAAAGAATTAAGGCCGGGCGCGGTGGCTCACGCCTGTAATC CCAGCACTTTGGGAGGCTGAGGCGGGCAGATCGCCTGAGGTTAGGAGTTCGAGACCAGCC TGACCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGATGTGGTGG CACATGCCTATAATCCCAGCTACCCGGGAGGCTGAGGCAGGAGAATCACTGGAACCCGGG AGGTGGAGGTTGCAGTGAGCTGAAACGGCAACACTACAATCCAGCCTGGGCGACAGAGTG AGACTCCCAGCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAATTAAGCAACTGTGTT AATCTGTTTGCATTATTAAAAAGCAATAACTGAGAGTGGGTAATTTATAAAGAAAATAGG TTTATATTTGGCTCATGGTTCTGCAGGCTGTACAGAAGCATGGCACCAGCATCTGCTTCT GTGAGGGTCGCAGGAAGCTTCCACTCATAGTGGAAGGTGAAGGGAAGGCAGGCGCATCAC ATGGTGAGAGAAGGAACAAGAGAGGGACCAGGTTCTTTGAAACAGCCAGCTCTCGTGTGA ACCAACCGGGTGAGAACTTGATCATTACCAAGGGGAGGGCACAAAGTCATTCATGAAGGA TCCCCCCCATGACCCAAACACCTCCCATGAGGCCACACTTCCAACACCGGGGAGTATCAC ATTCCAACATGAGATTTGGAGGGAACAAACACCCAAACCGTGTCAGCAGCCAAGTGAAAT TGTGTGTGTGAGAGAGAGGCAAAGAGAAAGAGAAACAGAGGAGGAAGGCAGACAGAGAAA GAGAGTGCATGCAACTAAGCCTGTGTGCACACACTGAGGGGCTCCAGGGCATTGGGAATG AAGGAGTACAACTCGACTCACAATAGGAATTGCAGCATGTCCTAGTTATCTAAAACAAAT TACTCCAAAACTCAGCAGCTTAAAACATTGAACATTTACCATCTCACAGATTCTGAAGGT CAGGCATGAGGGAGCAGCTTAGCTGAGTGGTTCTGGCTCCGGATTTCCCCTGGGGTTGCA GGCAAGCCCTCAGGCAGGGTTGTAATCTCCAAAGGCTTGCTTCCAAGCTCACTCACTTTC AAGCTCATTCACGTAGCTACTGAGGAGCCTTTTTCTCCTCTCGATGTTGACCTCTTTATG GACCTGATCACTACATGTCAGCTGGTTTTCCAGAGAAAGTGGTTGACAGAGAAAGAGACC CCTAGATGGAAGCCACTGTCCTTTATCTTAGAAGTGACATATCATTTCTGCTATATTCTA CTGGTCACACAGACTAAACCTGGTAACATGTGGGAGGCAACTACACGAGTGTGAAGACCA GATCATCACAAACCATGCTGGAGGCTGGCTACAGAGGGTAGCAGAAAAATACCTCGCAAA TAGAAAAGGCCTTTTAGAACATCGTGTTGTGATATTGCAAAATATATATTTGGTCTGTCC CCGTTTCCTGACATAGAGCTCCTAAAATCTTTGGAATCTCCAGAGTGATCAGAGTGTCTT TGCGTATTAATGAGATAATTAGTAGCTGGGGGTTCCTAGATAGCCTCAAGATGGGGTCTG GTGGCCAGGGGAACCAACCATGTGATTAGAGGGCCGGAAATTTCAGTCCCACTCCCAACT TGTTGGGAGGGGAGAGGGGCTTACAGTTGAATCGATTAACCAACAGCCAATGATTTAATC AACCATGCCTATGTAATAAAGTTTCCACAAACAAACAACAACAACAACAAAACAGTTCTG GGAGCTTCCAGATGGCTGAACCCATGGACGTTCCTGGAGAACGGCATGCTCAAAGGAGAC ATGGAAGCTCCATGCCCCTTCTCCCACACCTCGCCCTATGCACCTCTTCCATCAAACTGT GCATATTTATCCTCTGGCATATCCTTTTTAATAAATGGGTAAATATCAGAAAAGTGTTTC CCTGAGTTCTGTGAACCACTCTCCAGCAAACTGATCAAACCCAAGGAGGTGAGTCATGGA AACCCCAATTTACAGGCAATGTTAAAAAAAAATTCTGATTGAGTCTGACTGACTAGCTCT GTCACTTTAAATTCGTGTGTGAACAAACCAAAGCCCAATGTAAACAGTAAACTGAAACTA GAAACTGCACCAATCAGAAATCACCAACTAACCTCTAACTAGAAACTTTCCACTCTAACC AATCAAAATTGGTTTCATTTGTGTTGCTTCTGCAAATACTTTATAAAAGTTTCCCCTCTT GCCCCTGTGGGCAGAGTGCTAGCCCCTTGTGGTCTGATGCTACCCCATTCACAAACTGCT GAATGCTCAACTAAACTGCTGAAAATGTAAATGTGCTTAAGATTTTCTTTTATCAGATCT GATATCAGAAGTGGGATCCAATGGACACTACATGATAATGACCTCTGGGAGCAACAAGCA AACAGATACAGTTACCCCACAGAGCCCCTTGTGCTTACTCCCTGCACATTTGGAGGTCAT CACCAGTAAGTAGACTTAGATACGTGCATTCTAACACTAGCGTCAAGTTCTCCAAGTTCA TTTTAACATTTCTGCTCCAGACTAGGTTTGGAAGTCACAGCAGAAACAAGACTGGGTTTT GCAGGGAGGCTTCAGGTGTCCAACTAGGTTAGACAAAAACCAAACTGGGTTAAGCAAAAG ACCTCCACTAGGAAAGGTTCCACGAAGACTGGAAATAATGAGTTTATTTAAATCCAGAGT CTGGGACTCCATCTATAGTGTGACTGGTCCCCTACCAGGTTACTTAAGAGTGTATGTGTA TTGCTTGAACCCCAAAAGCTAGGCAGTGAACCAAGGCCACTGCGCCCAGCCAAGGACCAC GTGTCCCTGAGAACCTAAACATCCTGGGGCATAGCTGGGGACATATCAAGGAAAACCACA CAAAATTGACAAAGGGCCAGAAAATTAACTTAAAAGCAGCTTAGAAATGGGAGGTGGTGT GGATCTCTAGAGCTGTCCAGCCACCATCCAGGAGTGTCCTGAAGTTAAGTCCTAACAAGC TCATCTAGCCGTCAAGCTAGATTTATCCAAGTTATTCTTTGGTCTCCCAGCTCCTTCCCA GTTTGGGGGTGTGGGGAGAAGGATGTTATAGTCTCAAGTGCTTCTCATAATAGCATCTCA GAACCTAAGCTCTTCTAAAAGAATGGGCAAATCTTACCAAAAGCAATTTAGAATTTTAGT GGCTACAAAGTGGAAGTTTTTACCTAAACAAAATTGTTCACCTACATACACACGTACACA CACGATCTTGAACATCTCAGAAAGTGGGAAGGGCCAAGCACGGTGGCTCACACCTGTAAT TTCAGCACTCTGGGAGGCTGAGGAGTTTGAGATCAGCCGGGGGAACAGAGCAAGACCCCA TCTCTATTTAAAAAAAAAAAAACAACAACAAAAAAAACAGAAATGAGAAGTATTTTTTAC TGGCATGTAGAGGTTTCTAACCTCTCGTCTACTCTGAGTCTGCTGATTTTTTTTTTTTTT GCTTGTTTATCTGCATGCCCTGAAGGAAAAAGAACTAAATGAGTATTTATAGTTAGGTTC TCAGATTAACCAGGTCTGCTTCTTTTTAATAGAACATTTTTAGGCTGGGCGTGCTGACTC ACACCTGTAATCCCAGCATTTTGGAAGGCCAAGGGAGGCATATCACTTCAGCTCAGGAGC TCAAGACCAGCCTGGGCAACGTGGCGAAACCCCATCTCCACTAAAAATACAAAAATTAGC CAGACATGAGGGCGCACACCTGTAATCCCAGCTACTTGGGTGGCTGAGGTAGGAGAATCA CTTGAACCTGGGAGGCTGAGGCTGCAGTGAGCTGAGATGTGCCACTGCACTCCAGCCTGG GCAACAGAGTAAGATACTGTCTCAAAAAAATAAAAAATAAGAAAAATTTTTTAAAAGAAA ATTTTTTACTTAATTCATTTCTTTTTGTGATAGGGTCTCCCTCTGTCACCTAGACTGGAG TGCAGAGGCATGAACACAGCTCACTGTAGACTCAACCTAAGGGAAGAGACCACCCCTCAT ATTGTCTTATGCCCAATTTCTGCCTCCAAAGAAAGAAGTAAAAACTAAAAGGCAGAAATG AAATCCACAGGCAGACAGCCCAGCACCACACCCTGGGCCTGGTAGTTAAAGATCCACCCC TGACCTAATCGGTTATGTTATCTATAGATTACAGACATTGTATGGAAAAGCACTGTGAAA ATCCCTGTCCTGTTCTGTTCTGTTCCTTTCTAATTACCGGTACATGCAGCCCCCAGTCAT GTACCCCCTGCTTGCTCAATCGATCACGACCCTCTCATGTGGACCCCCTTAGAGTTGTAA GCCCTTAAGAGGGACAGGAATTGCTCACTTGGGGAGCTCGGTTTTTGAGCCATGAGTCTT GCTGATGCTCTCAGCCGAATAAAGCCCTTCCTTCTTTAACTCAGTGTCTGAGGGGTTTTG TCTGCGGCTCGTCCTGCTACAAACCTTCTGGACTTAAGCAATCCTCCCGTCTCAACCTCC CAAAATGCTAGGATTACACCCATCCCAGGTCTGCTTTTTTTTTTTTTTTTTTTTGAGATG GAGTCTGGCTCCGTCACCCAGGCTGGAGTGCAGCGGTGCAATCTTGGCTCAATGCAACCT CTGCCTCCCGGATTTAAGCAATTCCCCAGCTTCAGCCTCCCAAGTAGCTGGGATTATAGG TGCTCACCACCACGCCCAGCTAACTTTTGTATTTTTAGTAGAGGTGGGGTTTCGCCATGT ACCCTTATGTCTTGATCAAAATCTTAATCTCAGAGCAATAATAAAAGGTATCCCTGTCTG GCAGAGAAAATGCTTTGTCTGCCCTATTCATGAATGGGTTTTGCTCTGAACTTGGCAACC TAGGTAAACATGGATTTTTTTCCTATTTTTTTGTGGGTTTTTAGATTTTTCTAGCTTTTT TGGGTACAAAGTAGGTATATATATTTATGGGGTACATGAGATGTTTTGATACAGGCATGC AATGCATAATAATCACATCATGAAGAATGGGGTGTCCATCCCCTCAAGCATTTATCCTTT GTATAACACAAAGGACAATCCAATTATATTCTTAGTTATTTTTAAATGTACAATTAAGTT ATCGTTGACTGTAGTCACCCTGTTGTGCTATCAAACAGTAGGTTTATTGTTGTTGTTGTT GTGGTTGTTGTTGTTATTTTGAGACAGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTG GTGCGATCTTGGCTCACTGCAGGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAG CCTCCAGAGTAGCTGAGACTACAGGTGCACGCCACCACACCCGGCTAATTTTTTGTAGTT TTAGTAGAGAGGGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCATGA CCCACCCGCTTCGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACTGTGTCCAGCC TCAAATAGTAGGTCTTACTCGTTCTATTTTTTTTTTTTTGTACCCAGTAAACTCATGTGG ATAGGACATGAGGAAAGCCAAAATGGACGCAAAAGGCAGAAGGGTATCACTCTGAAGATG ATATCTGTGGCCATGAGACCCAATTTGGTTCATATATAAACCACAAAAAGCAAAAAAAAA CCCCAAAAAAACATAAATAACCTTTTTTTTTTTTGAGACGGAGTTTCGCTCTGTTGCCCA GGCTGGAGGGCAGTGGCGTGATCTCAGCTCACTGCAAGATCTGCCTCCCGGGTTCACACC ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCACACCCAGC TAATTTTTTGTATTTTTAGTAGATACGGGGTTTCACCATGTTACCTAGAATTGTCTAGAT CTCCTGACCTCGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAG CCACCATGCCCGGCCATAAATAAGCTTTTGAAAGCCATTCCTAAAGTGTTTCCCACCTGC ACTAAACCAGACCTGCAGACAAAAGAAAAATGAATCTGTTACTAATTTCAAAGCCCACTT GGACCTTTTGTTTTTCCTACAGCATTCCAAGCATTACATCAATTCAGCTAATCCTAGCTG TCCTTTTTGTAAATGGAGTCTCCCCACAACATTACCAAACAAGAAAGAGAGAGAGGAAAA GGATAAGGAAGCTACAGGGTTAAGTAAGTTAGCTGAGGACCTCAGAGCAAGATGAGAAAC AAAAGGTTTCCAAATTAATGGCCTTGTAATTATAGCAACTGCGGAGCAACCAACAACCAA GAAGGACCTTTGGACTACTTTTAATAAGTGACTCAAACCAGACGTTATCTCCTTCTGTCT GTCTTTGTATGAATGTTTGTGTGTGTGTGTGTCTATATATATACACACACATATGTGATA TTTTCAGATGGTATTACTAAACCAATTTATAAAATCCTTTAATGGAGATCTATTCAAATT GGTTTGGGGATAAATGAGCATGCATGTAAATTATTTCTAAAACTCTCAGAAATGCAGAAA CTGACCCAAATGTGTGTTTTTTTTTTAATAAGTTCACATGATTTACATAAGTCTGTGGTA AATAAAGCTAGTTTTTAAATTGTCGGTAAAATAAAATGGGAGTTTCTCAGAATTCTCAAG TTTTTCCTGGGTTGCTGGTTAGACAGATTGGTGTTGGCTCTGCTAGATGTTTAAGATCAT AAAACCATAAATCCAACCTAAGAGGAAAATGTGCAGTAAAAATGAATTGCTTGATCTTGA TGCACGTCAGTCATGGAAGTAAAAAACTGTGATACCTGCCTGATTTGTCAAGAAAAATTA AATAACATTAAGATGATGGCGTGGGAGAAGGCATGGATGATAGCTGAATTTCTTTGGAGG ACCTGTCTTTAGGCAGACAAAGGAGTCCCAAAAAGCCCCTCCCTGCATTTGTTATTTTTC AAATGCTTTCGGCTCAAAGCAATCAATATTCCAAAGCAGTAAATTTTGGAGTGGCATTTC CTGAACTCTTTCAATGGCTAACTCTGTTCAATATCTCATGACATTTTTCATGAGCAATTC AAGTATATTTGTTTAAGAAGGAGTGACTTAAATATAAATGGAATAAAAGTTTAAAACTTT TTGAAATTATGTTTTATAAAATGTCTACAGTCATAATCTTGATTATTATGTTAAAATGTT GTATGTCACAGAAAATAACCAGATTTTTTTGTCAGTTGCATTATTATAATGAAACCTCAT TAGAATTTAACTATGGCCATCTTAAGTCTTGTCATCCATAGGCAGTTATTGTTTTGATTT TTCTCTAAAAGCATTTGCAATCAGCTATAGTCCAAAATTGCTTCTTCTTCAAAGATATTC ACGGAAAGAACTCTGACAAGTACTCTGGATATACAGGTTTCTTATAACTTTAAATTAAGA TAATGCCATGAAAGTGGGTAAGAATTCTCAGAACGCTAATAAAGAAACTGGTGAGTTTGT GAAACTGCTATCCCGAGATCATGCAGAACAAGAATTACATAAGACTGAATAACTGATGAA AATAATGTTTTTATGACTTTATATGTGGAAGTTTTGCTGGTTCTTTAAAGTTTTAAGAAA CATTTTACCTTTTAAGCTATCTACTGCTTGCAGCAATTTGGAAAAGTATACTTTTGTGAA TAAAGATTGAAGTATTTACTTTTCCTCTCTACCTGATCCTCGGGAACTTGGAAAGCTACT TGTGAAGATTTTTTTTATGGCAATATAACTATTTGCATAAGTTCAAAAAGAATCTGTTCT CTTTATAACAAGACACAATTGGAAACATTGGTTATATTACCAAGGGTCATATTTGACAGT GTGCATAGAATGCCTGGCTAAAAGTGTTCCCAGTCTCACAGTGAGTGAGTAAAAGCTATC AGTTCCCAGCAGACCCAGGAACCTCAAGATATTTGGGGGACCTTACGAGAAGAGAAGAAT TCACCCAAATATATAGGTACTGCAGGTGAAGTCTAAAATTTGCCTTGGTTTGGCTTCCTA GATTTAAGAGGTTTTTTTAAAAGTTCAATCTGATTCCCTATCAAAGGTTCCAGCAAAACA AACTTTAAAAAGAACTTGTGCGGTCAATCACTATTCTTACTGCACTTACATAATCAGGCC AAGTCTGATGAGACAAAATTTATTATGCAATCAAATTAGTCTTACACTGATTATTATTAT TATTTTTGGAGACGAAGTCTCAAGCTTGTCCCCCAAGCTGGAGTGCAATGGTGCAATCTC GGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAACCTCCTGAGT AGCTGGGATTACAGGCACCTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGAC AGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGC CTTGGCCTCCCAAAGTGCTGGGATGACAGGTGTGAGCCACCGCGCCTGGCCCATTTATCT TTGGTAGAAACAAGGATGACTACAGAGAGAAAATTATGTTTCAGAAAGAAACAATAGTAC ACCTGTTATTAGACTGCAGCCCTATTAACTGTTTTCAAGTTTTATTATCTACCTGTAGTT TGCACTGAATCCTCAGTTCTTCTAGGTTCCTCCATCCAATTTTCTCCCACTTTTCTGACT TGGAATCACTCTGAACAAGAACTGCTCTGCTCCTGAAACCCTGCAAGATGGAGATGTATA CCTGATACAAGTTCAGAGGACAACCCTCATGCCTGATGTGTGGACCACTCAGGGAGTTCA CCAAAATGCCCACTGCCATAACTAGGGGCATTCAAACTGCAAACCAGGAAAATATGCTTA GAGCTCAAATCTAGAAATCTTCCTGACTAATCACCCTCTGGACTCAGAGACCGAATTTAT GATTTGTTCTTATCATTAAGCTTTGTTTTTCTTTTGCTTCCATAGAAATATTAGTTAGTT TGGTTCGTGGGGACTTTAACTAAGAAGCTAAGTCTCTCAGTATTATCCTCCTGGTAGTCA TCATTATAATCTTCCTGGTGCACTATATTCTCTCAAGGGTCTTAAATGTATATTCAAAAA CATCAACAGCATACCAGATTGTCTCACTGTGATTAGAAAAAAAATGAGATTGACAACAAA AGGAATTGTTTTTCATTGAGCCTGTTGTCATGATTTATGAGTTCCACACTAAGACAAAGA CAACCTAGCCATGATGGTGACAGAGAGTGGCACTTACGTCCAAGTTTATAAATGAGAGGC TGACCAAAAGGAGGAAACTTATATGTAACTAACCTGCACATTGTGCACATGTACCCTAAA ACTTAAAGTATAATAATAATAAATAAATAAATAAATGAAAAAAAAAAAGGAGGAAACTTA AAAAAAACCATTCCAATTGAGAGTCCATTAGACTAGGGTAGGGTAGCTCTTGTCACTTTA AATCCCTAATCGAACAAACCAAAGCCCAATGTAAACAGTAAATTAAAACCAGAAACTGCA CCAATCAGAAACTACCAACTAATCTCTAACTAGGAACTTTCCACTCTAATCAATCAAAAT TGGTTTATTTGTCTTGCTTCTGCAAATACTTTATAAAAGCTTCCCCTCTTGCCCCTCCTG GAGGAGTGACACTCCCTTGTGGTCTGCTGCTACCCTATCCATCAACTGCTGAATGCTCAA GCTGTTTCGGCTGGGTGTGGGGACTCACGCCTGTAATTCCAACACTTTGGGAGGGTGAGG TGGAAGGATCACTTGAGGCCAGGAGTTCAAGATTAGCCTGGGCAACATAGTGAGACCTTG TCTCTAAGAAAAATAAAAACATAAAAATTAGCAGGGCATCGTGATGTGCACATGTAACCT CAACTACTTGGGAGGCTGAGGTGGTAGTATCACTTGAGCTCAAAAGTTCGAGGCTGCAGT GAGCTACGATATCATCACTGTACTCCAGCCTGGGCTACAGAGCAAGAGCCTGTCTCTAAA AATAAAAATAAAAAATAAAAATAAATGGTTTAAAAGTGCTTAAGTTTTTCTTTAACCACT GGTCAGTCAGAAATTCCATATTCTGGAGGCCCTGACTTTGATTGGCATCTGAAGTGGGGG ACAGTCTTATGGGACTGAGCTCTCAAGCAGTGGGATCTGACACTACCTCTAGATAGAGTC AAAATTAAATTGAATTAGAGGAGACACCAGAGCTGATGTCTGCTGCAGAACTGTTTGGTT AGTGTGTAGGGAAAAACCCCCATGTACTGGTAACAGAAGCATTCTGTGTGGTACTGAGTG ACTATGTTAGAATGGGAAAAGAACTTTGGTTTTTCCTATATCTCTACACTTACAAAGACA AAATTTTTTAAGATCTTGATCATATAGAATGATGCAACTAGCTTACCATTAATAAATCAT GCCCAGTGAGGTTTTTATCCAATAGTTGTAAAGAATTTGTACAAATGCATCTGACTATAA AATATATATGTTTGCAAGATAAAAAGGTTGAATAACTAGAAGATGTAGAAGGAACAAGTA CTCTTGGGTCAGGCAGAGCCAAGGATCAATGACAACTGCACAGCTCACAGGCTGTGTCAC TTAGGGAAAGTTTTCATCAGTGTAAGCCTCAGTTTTCTCACCTGTAAAATCTGAGTGATA TTTACTTACATCATAGGGTTGTTGTGAATGGCAACAGAATATGCTTAACATGCAATATGT ACAGTAAACAGTGGCATTTGTTGCTAAATAAACCATTGTATGTGTGAAATCAAAACATTA ATTGGCTCATATTCTAACTAAGTCACCATACCTGATGTGTGGACCACTCACAGAATTCAC CATGGCTCCAGAAGTAATAACAGTTTTTCCCACAGCACAAGGACAAATAAAATACCCAGG GTGACTGTTGAATTTGAAGATTACTTGCCTCACCTTCAGAGATTATGATTGAATACAAAC AATTGTAGCTAACACTAAGTGTGTACCAGGTGATAAGCAGTGCTCTAGCACTTCACATAA ATTAATCTACTTAATCCTCACAATAATTCTATGAAGTAGATATTATCATTATTCCCATTT TACAGATGGCGAAACTGAGGCACAGAAAAGGTAAGTAAGTATCTTGCTCGAGACCACCCA GTCAAGTAAGGGCAGATCCAGGATTTGAACCCAGACTGATTACCTTGAGCCTGTGTTCTT GGCCACTATCTTGCTCTTCCTCCAAGATTTGGGGCAGGTCCCAGGCATCTCTATGTTTAA CTAGTACCCCCAAGTGATTCTGGTATGAGTAGTCCATAAATAAAGAAACACTAGACTCTT GGTAGTAAAGAATACCAATAGTTTAGAAATCGTATCTCGCAAGTCTAAAAAAACAATGTA GAGTTTATTGGGCTAGTTAACTGCTGGACTTCTTTGCTAAGGTAGAAAAATATAAACCAA GTGGAAAAAAATTTCACTTCCAACACTGAAGCGACTTATCAGTTCACACAAATCTTCAGT GGTTTTCTTGCCTCCAGACTCTTCATCAGCAACCCCCCAACCCATTCAACAATATTCGAC CTGGCTTTCTATAATATTCTCCCTAATGAACTACAGGTTGAATATCCCTTATCTGAAATG CTTAGGGTCAGAAGTATTTCAGATTTCCGATTTTTTCAGGTTTGAAATATCTGCATATAC CTAATGAGATATATTGGGGATGGGAACCAAGTCTAAACATAAAATTCATTTATATTTCAT ATACACCTTATACATATAGCCTGAAGGTAAACTTATACACTATATTTAATAATTTTGTGC ATGAAACCAAGTTTTGACGGCAACCTGTCACAAGGTCAGGTGTGGAAGTCTCCATTTGTG GTGTCAGCTCTCAAAACCTTTTAAATTTTGGAGCATTTCAGATGTCAAATTTTCAGATTA GGGATGCTCAACCTGCAGCAGGTTCTATCTTCTGGCACCTTTTCACTAAACCCTACCTTG ACCACCTATTTAAAATCACATCTATGAAATGAAATATCATCTCACCCCAGTTAGAATGGC TATTGTCAAAAAGAAAAAAAAAAAAAACAAGTGCTGGCAATGATGCAGAGAAAAGGGAAT TCATATACACTGTTTGTGAGACTGTAAATTAGTACAGTAACTATGGAAAACAGTGTGGAG GATTCTCAAAAAACTAAAAATAGAATGACCATATGATCTACCAACCCTACTACTATTTAT CCAAAGGAATGGAAATCAGTATTTCAAAATGATACCTGAATCCCCATGTTTACTGCAGCA CTATTCACAATAACTAAGATATGAAATAAACCTAAACATCCATCAAAAGATGAAGAGATG AAGAAAATGTGGCATATACACACAATGGAATACTATGCTGCCATAAAAAAGAATGAAATC CTGTCATTCACAGCAATATGGATGAGCCTGGAGGACATTATGATAAGCAAAACAAGTCAG ACACAGAAAGCACCTGCTCTCATTCATATGTGGGAGCTAAAAAAAATGTGGCCTCATGGA AGTAGAGAGTAGAAACTATAACTTATTCTATATCCTCAAAAGGCTAAAAGAGAGGATGTT AAATGTTCACAACACAAAGAAATGATAAATGTTTGTGGTGAAGAATATGCTAATTACCCT GATTTGATCATTACACATTGTATCCCGATATCAAAGTATCATTCTGTATCTAATAAATAT ATACAATTATGTGTCAAGTAAAAATAAGAGGCATATATAAAATCACAGGCCGGGCATGGT GGCTCACACCTGTGATCCCAGCACTTTGGGAAGTTGAAGCAGGCAGATCACTTGAGGCCA GGAGTTCAAGACCAGCCTGGCCAACATGGTAAAACCCCGTCTCTACCAAAAATACAAAAA TTAGCTGGGTGTGGCAGTATATACCTGTAGCTGCTCAGCAGGCTGAGGTGGGGGAATTGC TTGAACCCAGGAAGTGGAGACTGCAGTGAGTGAAGATCGTGCCACTGCACTCCAGCCTGG GCGACAGAGTGAGACTCCATCTCAAAAAATAAAATAAAATCACAACTCTGCCTTTCTCCC TAAACCTCCACCTATACACCCATTCCCCACTACCCTACTTTTTAAATTTTTTCAACAGAA TATATTACCTAGCATACTATATGATATACTTATTACACATAGTAATATTGACTGCCTCCT CAACTAAAACATAAGTTTTAGAAGCAGGAATTTTTTTTCTGGTTTATTTTGCTCATTGTT ATACCCCAAAATGCCTAGAACAGTGCCTGACACACATAAATATTTGTTGCATTAATTAGT TAATTAATGTCATTGTCCAGCTCAAAACTTTCAATAGCTCCCCACTACTAATCAAATAAA ATCCAAGCACGCTCTCAGGGAATCTGGACACTCCAAAATTAGGCCCTAACTGACCTTTCC ATCCTTAATTTTTCCTAAGTCAGACTCAGAAGTCCAAGAGTTGACATTTCCTTACTTCCT GCTTTCCTGCCCCTGTGCCTCTGTTGATGTAGCCCTTTCTGGCTGCCTTGCCTATACCAC AATATCTTTATCTATCAACGTGATGCCTATTGTGAATGAGAAACTACTCTCCAAGGTCTC TGAAACGGTGTCTGTTTCAAACACATCCCTGAATTCAGTGGCGTGACAGGCTCCACTCCT AAGGCTTAGTTTCTGCCAAGTGCCATCTTCCATGCTTCCATATGTTGTGGTTAATTGTGT CTGAGTCGTACCCCTCCACTGACGCTAGCTAACTGAGGGCCCTGATGGTCTGGGATTTGA GGTACATCTGTACACAAAGAATAGCTGCCTATTGCGTTGCACATTTTACAAGTCAGACAA TGGAAGGGGCCTGTTGCTTATAATGCTCCTTTTGTTTTTTGAAAATTTCTGCCACATGCA CCTTTTTAAGCTTTTTGACTTTTTTAAACACAGAGGGCTGCCCTACATTCAACCACTTAG GCCCACTTTTGAAGCCCAGGCCGACTGGAGAGTGCAAAGAGCAGCCAATCTGCAGACTGA AGACAGGCTTGGCAGAAAGTCTCCGCCCGTCTACAGTGGTCTACAATGAATAAAAAACAG TGACCTGACAAACCAATCTGATCTCTCCTCTGAACAGGAGTCTAAAATGGAGATACCAAG AGTCAGTACTTACCAATGGGCACAGAAGCCACAATGACCTACAGAGAGATGACGAAAAGC AGAGCAAGAGAGCAGAAGCTATAAGGCTTCAATAAACAAGAAAGATCAAGAGTCATACAA GCGGCGGAAAAGGCAGCAGAACCATAACAGTAGAATGTCACCTAGAGAGAAGGAAGGGAG GCAAGAGAGGAATGGAATGTCATCTCTGAACAGCCAACTACTAGATTTTCAATCAAGCTC CCTGCAGAGGGCAGACCTTACAGACTAACTCCTGGAAGACTGCTGTATCCCCAAAACATA AACTTAACTGTGTGGCTAGTCCTACTTTTCTTATTCTCTATGAATTCAATAAAATCCATC ACTTGTTTCTTGAAGCCTAACAGAGCCTATTTATATGGCAGTAATACCGTGTGATACATG GCAGTGATACCAGTCCAGAAGCCAGAACGGAAATGGAGGATAAATCTGACCACACAAAAC TTTAAAACTTCCGTATGGCAAAAAATGTTCAACAAGGTCAAAAGAAACTATAAACAAGGA AAAAATATTTGGAAGACATATGACAAAGGCTAATTTCTTCTTAATATAACAAAAACTTGT TAAAATAAATAACCCAATAAAAGACAAAGAAGTAAAGGATATCATAGTATAGAAAAATAA ATGTAAATAGTGCAAACTCTATAAAGGATAATTTGTCAATATCTACTAATATTGAACATT ATATCCCTTTGACCTAACAAATCAACTGCTAAGAATTTACCCTCAGAAACACACTATCAC CAAAAGTACCCTACAATATATCAAAAGATATTAACTGTGGCATTATTCATAACATTAATG ACCATAAATAGGTTAGTTATGGAACACTATGTGGTCACTAAAAGATGAATTCAATTTTTA CAAAAAGATCTCTAAAATATAAAGCATTAAAAAGCAAGGTAGAACTAAAATCCTGAATTA AAACAGCAATCATTATTGCCAACCATACAGAATAAAAAGGATTATAAAGTAATACTATGA CCAACTGTGTGCCAACAGATTGGTTAGCTTAGATGAAATGACAAATTCCTAGAAAGACAC AAAATCCTGAAATTGACTCAAGAATAAACAGAAAATCTGAAAAGACCTCTAACAAGCAAA GATATTCAAAAACCACCCACATGCAAAGGCCTACTCCCAGATGGCTTCACTGGTGAATTC TACCAAATATTTAAAGAAGAATGAATACCAATTATTCACAAATACTTTCAGCATAAAATA GAAGAGGAGGAAATGCTATGCAGCTCAGTCTATGAGGCCAGTATTACCCTGCTACCAAAA TCGGACAAAGATATCACAAGAAAACGACAGACTAGTATTTCTAATAAATACAGACACGAA AGTCCTCAGCATAATACTAGCAAACCATTATCTAGGAATGTTAAAAAAAAAAAAAAAGTT TATTTAGTATGAGCAAGTAGAATTTATCCCAGGAATGTAAGTTTGTTTTAACATCCAAAA ATCAATCAATGTAATCATATCAATAGATAAAGGACTAAAACATATGATCATCAAAATAGA TGCAAGAGACATAGAAAAAGCATTTGACAAGATTCATCACCCTTTATGATCAAAACACTC AACAAACTAGGAATGTAAAGGAACTTCCTCAGTTTGATAAAGGGTGTCTATGGAAAACCG CAGCTAACATCTTAGTTAACAAAGACCGAATGTTTTTCCCCTAAGACCAGGAACAGAAAG GGTATTTGTTCTTATCACTTCTATTTAACATTGAACTGGAGGTTCTAGCCAGGACACTTA GGCAAGAAAAAGGACTAAAAGGCATCCGTTTTGGAAATGAAAAAGTAAAACAATTTCCAT TTGCAGTAACATAATCTCATGTATAGAATAATAAGGAATCCATTAAAAAACTATTAGAAC TCATAAATGAGTTCAGCAACTTTGCAGGCTTATAAGATCAATTCACAAAACTTATCACGT ATCTATACAATTTCAATGAATAACCTAAAATTGAAATTAAGACAAAATTGTATTTACAAC AGCATTGAAAAGAATACATTTAATAAGAGAATTTATACTTTGAAAACTACAAAATATGGC TGAAAGAAATTAAATACATTTAAATAAATGGCAAGTCTAAAAAAATGGGAAGACATCCAT ATTCATGGGTCTGAAGACTTAATATTGTGGAGATGACAATACCTCTCAATCAATTTACAG ATTCAGTGTAATGCCTATCAAAATCCCAGCTGACTTCTTGACAAAAATTGACAAGCTGAT CCTAAAATTCTCACAGAAATTCAACGGACCCAGAGTAGCCAAAACAATCTTGAAAGAGAG AACAACTTAGAGGACTCATGCTTTCTTTTTTTTTCTTTCTTTTTTTTTTTTTTTTGAGAC AGAGTCTTGCTCTATTGCCCAGGCTGGAGTGTAGTGGTGCAATCTTGGCTCACTGCAACC TCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAG GCGCGTGCCACCACTCCTAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCAT GTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCAGCCTCCCAAAG TGCCAGGATTACAGGTGTGAGCCACCGCACCCAACCCAGACTCAAGCCTTCTAATTTCAA ACTTCACTACAACACTACAGTAATCAAGATAATGTGTTATAGATATAAGAATAGACATAT AGGTCAATGGAATAGAATTCAGAGTTCGGAAATAGACATTCACAGTTAAGGTTAATTGAT TTCTGACAAGGTGCCAAGACAGTCTGACATGGAAAAATAGTCTTTTCATTAAATGGTGCT GGGGAAAATGGATAGCCACATGCAAAAGAATAAAACTGGACCCCTACCTCAAACCATACA CTTAGAATCAAAGACCTAAATGTAAGGGTTTAAACTATAAAACTCTTAGAGGAAAACACA GATATAACTCTACATTGGATCATGCAATGGTTTCTTAGACAGGACACCAAAAGCACAAAA AAAGATAGATAAATTGGACATCATCAACATTAAAATCTTTTATGCTTCAAGCACACCGTC AACGAAGTGAAAAGACAACCCACAGAATGTGAGGAAATACTGTAAAATCATCTATCTGAT GATGGCATTGTATCTAGAAAATAAAAAGAACTCTTGCCATTCAATAATGAAAAGACAACC AAATTTTCAAGTGTGCAAAGAATCTGAATAAATCATTTCTCCAAAGAAGACATACACATG GTCAATTAGCACACACAGTGATGGCCAACATCATTAGACATCAGGGAGATGCAAATCAAA ACCACCTCATGCTTCACACCCACTAGAATGGTTATAATCAAGAAGACAATAATAAGTGTT GGTGACGATCCAGAGAAACAACAATCTTCATACACTCCTAACAGGTATGTAACACAGTAC AGTCACTTCAGAAAACCGTCTAGCATTTCCTCAAAAGGTTAAATATAGAAATTACTGTAT TACCCCATAATTGCACTCCTAGGTAAATATCTAAGATAAATGAAAACAATATGTCTGTAC AAAAAAACATGCACAAATATACACAAGTATTCAAAGTAGTTAAAAAGTAAAAACAACCCA AATGTCCATCAACTGATGACTGAATAAATAAAATATGGTACATGTATACAAGGGAATATT ATTCAGCAATAAGGAAATTAAGTAATGACAGATGCTACTCCATGGATGAACCCTGAAAAC ATCATGTGACGTGAAAGAAGCCAGACACAAAAGACCACATATGTATAAACCCATTTATAT GACATATCCAAAATAGGCAAATTTATAGACAGAAAGTAGATCAGTAATTGCCTAGGGCTG GGAGTAAGGAAGTGGGGAGAGGAATGAGGAGTGACTGCTAATGGGTAAGGAGTATCCTTT TGGGTTGATGTTCTAAAATTGTGGTAAATGTTGTACAAGTATCTGGATACACTAAAAACC AATGAATTATAGATTGAATGAGCTGTATGGTTATCAGAATTATATCTTAAAGATGTTATT TTTTTAAAAAGCAAAGCAAAGAATAATGTGTATACTATCCCATTGTAAACTTCTACCCGT GGCTTTGTGTATGTGCTAGTACATGGACAGTTTTCTGGGGGAAAAAAAGTCAAGAAATTT AACAGTAGTTTACTTTGGGAAGGGAAACTATAGTGAATGAGTTCAAGAAAAAGGGATTTC AATTTTTTACTTTATACCTTGCTGTTCATGTAAAATTTGTTTCACACCATGTGAAAGAAA ATATAAGCTTCTTTAAAATTAAAAGAATATATGGCCTTTAAAACCACACAGTACTGGCAT AAGAATAAACAAAACATTTGAAACAAGTCCAGAAATAGATCCACAAATATAAAGGAATTT AATGTATGAAAATACTTACATTTTATATGAGTGGAGAAAAGATAAATCTTTCCCTAATTC AAGCCAGAAATTCCAGATGAAATAAAAAGCTATAGCAGAAAACATTAGAAAATATACACA ATTAAAATGTTAGAAAAACTACAGGACATTAATAATTTGGGTACTGATGGGATCTCTCTG GGATAAAAAACTCAAAAGTTACTAAGAGACTGACAAATTTGACTATATACTATTAAAACT CTGTTATGATAGAATAGCACAAGTTAAAAGACAAGTGACAGCCTGAGAGAAAATATTTAT AACAGACAGAGGTTTACATACCTTGTACCATGTATATATATAAGGATTCAGTAGATGGTA TCTAAGCACAACAAAATTGGAATTAAATGAATATTTCTAAAAAAAAATAATAGGCTGGAC GCGGTGGCTCATGCCTGTAATCCTAACACTGTGGGAGGCCGAGGCAGGTGGATCACCTGA GGTCAGGAGTTCAGACCAGCCTAGCCAACACGGCAAAACCCTGTCTCTACTGAAACTGCA AAAATTAGCTGGCCATGGTGGTTCACGTCTGTAATCCCAGCTACTCAGGAGGGTGAGGCA CGAGAATCACTTGAATCCAGGAGACAGAGGTTGCAGTGAGCTGCCACGGCACTCCAGCCT GAGCGACAGAGCAAGACTCTGTTTCAAAAAAAAGAAAAGAAAAAAAAAGAAAAGAATGGA TGGATTGAATGACAGGTTGATCCTGTAAAAGCTATCGATGGGACTAAAACACAATATATG CATAGAAGTGAAGTGCTGCTTTAATCTTTGAAATGGCTTGCACTTTTATCAACATTGTCA TTTGACCTTCTTCAGTTAGCAATATAAACAGAATGTTTACTAAAATCATTTTGGCTAAAA AATATCTAAGATAAATATTTCACACTAAGAAGGCTTTCTTCAGTTGCCTTATGTCTTATA ACATAGAGATAATATTCATTTGTCATTTAAAACAAAAAATCAGACTGGACGGGGTGGTTC AGGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGTGAGCAGATCACCTGAGGCCAGGAGT TCGAGACCAGCCAGGCCAAGATGGTGAAACCCCCATCTCTAATAAAATTTCAAAAAATTA GCTGAGCATGGTGGCATGTGCCTGTAGTCCCAGCTGCTTGGGAGGCTGAGGCAGGAGGAT AGCTTGAACCAGGGAGGCAGAGGTTGCAGTGAGCTGAGATCACGCCAGTGCACTCCAGCC TGGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAGGAAAAAGAAAAAATCAGCCT GAAATACAAACTTATTTATGTTGGTTTTCCCTTCTTCTACCCACAGAAATTTGTGAACAT ATCCAAGATCATTATCAAGACGTCAAAAGTCAACACTCTAACATTTTCCACCAAGAACAA ATAATCATGTTAACACTAAGGGTTATTTAAGGTGAACACAGCAAAACTGCTGCCCTTTCA CAGCCCCAGCAAAGGCAAGATGTGACAGGAGCCCCCAGTAAACATGAAAGTGACAAGACC CTTCTCCGTGCAGGATAAGAGGCCACATAATTCAATTCAATTAAAAGATTATGGCCATGG AGACAGAATTTTCACTGAATGTTTTTATAACGAGCTCTCAGAGAGTTTTAGGGTTACTCT TACTTAATGCAGCCATTAATCCCCATGAATACCGTACAGCAAACTAACAAATACATTGTG TAAAAGTAGTCAAGCCCAAACAGACCATCCAAACTAATCCCCTGAAACCTCAGGAGCCAC GTGGAAAATCTAATATAATTACCTCCCACTAAACTCTGTACATCTGTTACAGGGAGTTCC TACTGTGATTACATTCTTAGTGCAAATGCCTGGAATTAATTCCAAAACAATCCAAGCCCA GGCCTAACCAAGTGGCCTTCACGACGCAAAACCTGCATCGGATGGTCCTCTTTTATCTCC TTTCATCCACAGGTAGCCTGGTTTATAAACCAGGGCTCCAGTCTGGCTTTATCCCTTTCT TTATTCATTTACAAGGTTTTTTCATTGATTTCCAGCTGAGTTCCTACAGCTAGTAGTAAT AAGACACAGTAAAAGGGTTTTTCAAAAATTATAATTATGTAATTAATAAAGAAATTATGT TTATCATTATTTCTACTTCACATTTTTTTCTACTTCCCCTTTGCTTTGCTTACTTACACC TTCAAAAGAAAAAAAAAAACTCCTGTGCAATGATGTTTTATCATTATTGTCATTTTATAG ATGAGAAAGGTAAAATCAAATTATTTAATTTAGCTAAAATCTCACAAAAGTTCTCTCAAG AGAACAAGGAATCAGGTCTTACTACATAAGGGCTTTCTCTATGGTGACACGTCACATCTC AAAACAAAACAGAAAGTAAGACAAACCAAGCTGTGATGCAGGAAAACAGAGGGAACTGGA AGTTGGATAAAGGGCAGAATGAGTAAAAGCAGAGAGCAGAAGCAAGGTGAATGGGTAGCT GAGTAAGAAACAAGAGACAGAAGCTGAGCAGCCAAAACAAAAACAAGATTAAAAAGTGAG TAAAGAGACCCCATAGCTGGCTCCTCAGAGATGGGCATGCGCATCAGAGAGAAAAAGTAT CCTTAACATGACCCCATATGATAATCAGCTCATTAAAGCTCATGCATATGGACTGTATAT TATGGGATGGAGGCAACACACAAGCACATAAGGGCCAAAGTAAGCAGTCCACCTATCAAT TAAATGGCAGAGTCTGGCTAAAGATTAGGCAGCCTTGGGAAGAGAAGAGACAAAAAAACA CATACAAATACCCAAAGTACATCAAACTGATGCTGATCTCATTTCACAGAGATCAGTCCA CTCTCCTCTCTCCAAGAGTGTAATACAGTGCTTAATAAACTTTTGCTGCTTGCTTTGCTA CTTGTGTGTGTCACGTCCAATTCTTTGTTCAGGACACCAAGAGCCTGGAACTGCACGGCA CCATCCAGTGACAGTTGGAGTACACAGAGGGAAGAAGGTGTTCAGTCAGAAGCAGGATTC AGGCTGAATGCATGGTAATGAACAAGGACATGGCAATTCCACAGACAATAGTTTGGGAAA CCTTCACTGCTAGGCTGAGAATTCTGACGTCTGCCTCTAGGCCAGCAAGGGCATGCCGTG GCAGAAGCAGGTCAGCAGTGGGGCATGGAGTAGGAAGAAAGCCGGAACTGCAAGCATGCT CAGGAGCACTACTGAGGTCCTCTGAGCAGAAAGGCACCAGCTGACTTGAGACAAGGACAG TGGGTGGGAGGAAAGGAGGTAAGTGCTGGTGATAAGGTAGAGAGGTGACAGTTCAGGTCT GCATCTTAGATGAGTCTCTCTGGTGACTGTGGAGGACCAATTTGAAAGGGCCAAAAGCAG AGGCAGGAGGGCTCTGCAGAATCTATGTGAAGATGAGGTCCTGAGCTAGGATGCTGGTGG CTTAGAGGGGAATGTAAATGCTGAGAAATATTCAAAATAAAATGTGTAGGTCTTATTAAA TGAGTGTATGTAGAGGCTGAAAAAAAGGGAAAAATGACTCTCAAGACAAGGTGGGCGATG GTACCTCCGACCAAGAAAGAGAATGTAGGTTTAAAGAAAAATATATTCCAGCCGGGCACA ACAGCTTGTGCCTGTAATCCCAACAGTTGGGAGGCCAAGGCAGAAGGATTGCTTGAGCCC AGGAGTCGGAGACAAGCCTGGCAACACAGTAAGACCTCATCTCTATGAAAAGAAATACTA CTAATAATTCCATCTTGGTCAAGTTTATGGGATAGCCAAGTAGATGTGCTGCGTGGGCAG TTGGAAATAAGATTCTGATGCTGGCGGGAATAACCAAAGAAACGGCTTATAAATCATGAG CACAGAATTGTAGCTGAAAACTTGAAAATGTATAAGCTCTCTGAAGGAGGGCACAGAGAG GCAGGGAAACTGTCATAAAGGATGGACCAAGAATGTAGTCTTGGTTCTACATTCTTGGTA CTGGTCAAAGAGGTATGAAAAACACTGGGAGAGTTCAACATCTGGAAAGATTTGGAAATA GAGTTTCAAGAAAAGGAATGGACAACAGCGTCCAGTGCAACAGAATGTCTAGTAAGGAAG GAAAGGCAAGCAGGTGGTTACTGGTGATTATCAGCGACAGCATGTCAGGAAACTCACAAA GGAAAAGCCTAATTACCTGAGCTGAACATGACTAAAAGGTAAGAAAGTGAAGACTGAGAA CACATCCCTCTTTGGAGAACTGTGCAGGAAAAAGGGAGGTAACATGTTAGGCAATACTAG AGAGGGACCTGTAGCCAAAGAAGGGGTTATCAGCATGTTTCTCTCTCTCTCTTTTTGTTT TTTTTTTTTAGACAGGGTCTCACTCTGTCATCCAGACTAGAGTGCACTGGCACAATCTTT GCTCACTGCAATCTCGACCTCCCGGGCTCAAGTGATCCTCCTACCTCAGCTTCCCAAATA GCTGAGACTACCAGTGCATACCACCGTGCCTGGCTAATATTTGTATTTTTTGTGGAGATT AGAGATGGGGTTTTGCCATGTTGCCCAAGCTAGTCTCGAACTCCTGGGCTCAAGCAGTCC ACCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACCCTGCCCAGCCTGG CAAGTTTCATAGACTAAAGGCAATGGTCTTAGTCTGGACCTAGACATCAGTAGTGTGTAT ACGTACGTTTACACATACACATACACACACAGTATGGCATAGTTTAATTAGCAATTTTCT ATCTTAGTAGTGTGGCTTACAATTGATAGTGTCTTAAATTAGATGATATATGCTAGCTGT ATGTTTATATGAATTTCACTAGCATAAAAATAACATCACTCTAGGGGAGAAAGAATTTTT TTTTAAGAATAGCACTATCTAAATGATGTTGATCATCTTTTTTGCCATGCTTAGCACGTA TTCTGATCCCAGGACCATTTGACCATTAAGACAAACAAACAAACAAAAAAACCACCTTCT TTTTTAGAGTATTTTAGGTTCTCAGCAAAATTGAGCAGAAAGTACAGAGAGTTCCCATAT AGCCCCTGTCCCCATATATGCACAACCTCCCTTACTCATATTGACATCCCATGCCACAAT AATGTTTGCTACAATCGATAAACCTACACTGATACATCATTATCACCCAGTCAGCATCAG TTTCTTTTTTTAAAGCTTCCCTGATGATTCTAATGTACAAGTGAGTTAAGAAACCACTAG ACTCAGAGGTAATGGTTTATCAAGATGGGAAGAGTGGAGATTCAAGAAAGAGGGAGCCAA GGAGCAAGAGCATGAAGGACTACAGAGTCCAACAGATATGAAGATGCAAGCCTCAGCCCT GCACAGTGGCTCACGCCATAATCCCAGCACTTTGGGAGGTCAAGGTGGAAGGACTGCTTA AGGCCAGTAGTTGGAGAGACTAGCCTAACCAAAATATTAATAACGAGACCCCCTCTCTAC AAAAACTAAAGTTAGCCAGGTGTGGTGGCACATTTGAGGTTACAGGGAGCTACGATCCTG CCACTGAACTCCAGCCTGAGTGACAGAGAGACACTGTCCCATTAAAAAACAAACAAACAA ACAAACATGCAAGCCTTGCACAGCTGGCGATGATACTGATACTTCTTTTTCCAGTGGCAA TTAAGAAGCCAAAAGTTCTGAGAAATTTTAAGTTAACATTTTTCACAATTAATTTGGCCT TTTGATTTAAAAAAAAAAAGAGAGACTACTGCAGTTCATTCAACCTAAGATGCCACTGAC TACAGGATGTGTCTTGATTATAGAATCAATAAAATACAGTATTTTTATAATTCATTAACA TTCATTATGTCAACCCAATAGTGTCAACATCACACCCAATTTTAAGGTCCTAAAGACTCC TAAGTGATTAAAATTTAAATAGGAAATATGACAATTCAGCTACCTAAGAATACAATTTCT AGAGATAAACTATTAAACCTTGTCAGTCTCTAAGGTAACGCAACAAAGTTGTACATAAAA CCACTGACAGCTGTAGGCTCTAACACTTTTGTTATGAAATCCCACCCCAGAATCATCACA CACGGCCTAAGTGAGTATGTGAGGAGGACGTGAGCACTCTCAACAGGCTGTCCTGAATGC TCACAGCAAGGGGTGTATGTTCACTCAGGGAAATAAGAAGCCAGCATTAATATGGTGACA CAATCACAGATAAGCTGCAGTCTGTATAAATGTCCACACTCAGATTTATGGAGTCTGTAA AATTCACCTGCATATTTGATCTTTGCTTTATTTAATATCTATATTTTGTTTCATTTATTT TGATTTTGCTCCAATTAATTTCTGAAAAACTAAGCATAAATTTGTATTCAAGCATAAGAT TATGAATTACATACTATTTTGAGAAAGCAAGGGGGAAAATGTATTATCTCAAATTCTATA ACTTATTCTGGTTTTATTCTTTTCTTTCACAGGGAAAAATATTTTTGCTTTTTTATTTTT CTTTTCATTTTGAAATACTCATTGAGGTTTTTTTTTTTTTTGCAAACATTCTCTGTTCAT CCCAAATGGATTTTAATTACGCATCATTTCTCTCTGACTGAAACAGTAAACAATGCTTTT GCTTTTGAAGATAAAAGTTTATAATTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTCACT CTGTTACCCAGGCTGGAGGGCAGTGGTGCAATTTCGGCTCACTGCAACCTCCACCTCCTG GGTTCAAGTAATTCTCCCACGTCAGGCTCCCAAGTAGCTGAGACTACAAGCATACGCCAC CATGCCTAGCCAATTTTTGTATTTTTTGGTAAAGATGGGGTTTCACCACGTTGACCGGGC TGGTCTTGAACTCCTGACATCAAGTGATCCACCCGCCTCAGCCTCCCTATGTGCTGGGAT TACAAGCATGAGCCACCACGCCCAGCCAAAAGTTTATAATTTTGATTTTAAATTATTTAC AACAGTTTCATTTACAATAGCATATCAGGCAGGGCACAATGGCTCATACCTTTAACCCAA TACTTGGAGGTTGAGGTGGGAGGGTGGCTTGAGCCCAGCCTGAGCAACATAGAGAAACCC TGTCTCTACAAAAAAATTTTTTAAACAGCCAGGCATGGTGGCATACACCTGTGGTCCCAG TTACTCAGAAGGCTGAGGTGGAAGGATCACCTGAGCTCAGGAGGCCAAGGCTGCAGGGAG CTGAGATCATGCCACTGTATTCTAGAGCCTGGGCAATGGAGCAAGATGATGTCTCAAAAA AAAAAAAGAAGAGAAAGATACCATGTTAAAAGAAATTTTGTACAAAAGAAATTCAGGTTT AGAAACCACTGTCAAACAATCAATTGACTCATCAGCTAACTATAAATGTAAAGAATCTTT TGATACAACTTGAAACATTTCAACACTCTCCAGCTCTCTCATCCAAACTGATGGCCTGAA TATTTTTGATGGATTATCATCCTCCTGTGTATTATAACTTCACTTCGTTCACGTTCATGT ATATTTTGATAATTTGACAATCATTGTATAAATGCATGAATGTTAACTATAGAGTGAAAC TGACAGAATGACAAAAAATTGACAGGATGTTCATATCTTCACAAATCTAATTACTTACAA ACTCAAAAGGTAAAGATGGCAGCCTGGCTATAGAGCTCTTGGTTCTTTTTCTCTAATTCT ATAATTCGAATTCTGTTTTTCACATCCAAACAGGTGGGAGTAAAGCCACCATGTGGACAG ATCCTGGGTTCCTGAGTTTCCATTTAATGGAGCACTGCCAAGAAGAAAAACCCAAATAAA GACACTGCAAATCAGACCAGCAAGTGTTCAAATTTTATTATGCAAAGAAACAGAAACTTT GAGATTTTTACAGGAATTATCCTATAATCTAGAACCTGACAAATACAGGTCCCACTTGTG ATTTCTAAATAAACACACACACACACACACACACACACACACACACACACACACACACAC ACAGAGATACATAATAAAAAATATAAAGGTAAATACTAAAACATTATAGTGGTTCTCTCT CAAAAATAGGACTCAAAAATCAGGGAAGTAGATAGCAATGGTTTTGTTTTTCACTTTGTA CTCTTCTGTGCTGCTTGGTTTTGGTTTGTATTTCTGTTTTGTTTTTTTTTTTACATTTTC TAACAAGCAGCTAATGAAAATTAGATAGCTGCTGAAAATGTCAAAGGCTATCTTAAATTG CCAGCTGTCCGCAGTACTATAGACTGTCTTATCACATTACTAAGTAAACAAAAGAAACAA TTATCTCATAATGTCCATTTCAACCTTTATTATCTCACTTGAAATCTGTTCATTTTGTAT ATTTTTAAAATTTATTTTTGTATATTTTTATTCTGATTTTTACTTTTATTCATAGAAGGA AAACAACATATCACCTCATAATGGTAAACTCTTTAATAAGTAAGATATTTTACTAAAAAT TTCAAGTACATTCTATTTTTCTGTCTATCTTGAGTGAATAGATAATAATTTATCATTGGC CGGGAGCAGTGGCTCATGCGTATAATCCCAGCACTTTAGGAGGCCGAGGTGGAAAGACTG CTTGAGCTCAGGAGTTCAAGACCCCTAGCCTGAGCAACACAAGGAGACCCTGTCTCTACA AAAAAAAAAAAAAAAAATGCTGGGCATGGTGGTACACACCCATACTTCTCAGCTACTCAG GAGGCTGAGGTGGGAAGACTGCTTGAGCCCACGAGGTCAGGGCTGCTGTGAGCTATTATC ACGCCACCACACTCCAGCCTGGGCAACTGAGCAAGGCCCTGTCTCAAATAAAATAAAATA AAATAAAATAAATTTAAATGTTAAATATTAAAAAAATTAATAAACAGTATCAGACAGATA CTAATACTGGTAATATTAGATATTAAGATGTAATACTGTATCAGACAGTATTACCATTTC CATCAAAATTTGCAGTAAATTTTAAAGAATTCACTTCTTCATTTGTTTCATGTTTTCTAA ATTTCTCTTGATCATTTTTACATCTGGGTTTTTTTTTTCAGGAAGAAATGCTAGATTAGT ACCAGAATGATTTCATTCTCTGTAATGTTACATTTCAACTATTTACAAAAATATAAATTA CAAGATTTTTAAAAAACATTAAGCCTTTGAAGTTTGCTTGAATGTCTTCTAACTTGAAGA TAAATTTTGATTGACATAGTCATTCACTTATTTTCAAGAATTTGGTGGATAAGCAAGATT CAAGCTTGATACTTCCTAGTTCTCATCTCCTATATATTAGATATACATGAATTTATTAAT AGTGAAAAAATTATTGGTTGTTCCCCACTATTCATATCTGCTTGCCTCAGAACATAAACT CTTTTTAAAATTTTTAAAAAATAATTGCTATTATTTTAAAAATCACAACCAGTCACAAAG TATTGAACAAATGTTTAATTATAAAATAGTATATTTACACAGGCATACAATTTGTATTAA AATTTATATTAAGTTAACAGCATGATTATATTAAAAGTTGTATGCTCATGAAATTTACAT TTAAAATTCCCATACAAGCATTACAAATCTGCTAAGACATTGACACGAACAACAAATCCT TCTACACGGGACGTAGAATGCTGGCCGGATAGCAACGTCAGCACTGGAATTTGTCAGCTG AGCCATAGCTAAGTGCTCATCACTCTTCTTTGCTCTTGTATTCTACCTGCATGTTGTTGT TTTATATTTCCCTGAGAACCACAATGTATGTTCCATAGTTTGTTTAGCTGATTTCACTGA CTTTAGCAATTAGAAAGGAGAACCGTGGCATCCTCCCCCGACTTCTCTCAAATCCTAACT CTCATTTCTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCCATCACCCAGGCTGGAGTGCA GTGGCGCGATCTCAGCTCACTGAAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCT CAGCCTCCTGAGTAGCTGGGACTACAGGCGCACGCCACCACACCCAGCTAATTTTTGTAT TTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCTATCTCTTGACCTCAT GATCCACTGGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCGTTGCTCCCGG CCACTCTCCTTTGTTTCTAAATGATCATCCTGGATAAGAGGTCAGCCAGGTCACGAGTTT TATATTCTGAAGAAGGAAAGTGACAAGAAGCCCAAGAGGTCACACCGAATTGGCTCAGAT TGCTCAGAGAGAGAAGACAAGAGCATCTGCTGAGATGAAGAGGAGGTGGAGGGAAAGTTT TGCAAGTTTGGAATAGACATGGGGTGGAAAGGATGAAAAAGGGAACAGACACAGACAAAA TCACAGAAGTCAGTATTTCAGGCTTGATGAAACCACCATTAAAAACTTCTAACTTACTTT GCAATGTCTGGTTGCAGACAAAACCCAAATTATGTCATTACACGGCTTAAAATCCTTCAG TGGTTTTAAGGACCGATTGCTCTTAGGACCACGTTTACTCCTAAATGTAGCAGATTTTTT AGCCCTCTGATTTCTTCCTACCAGTCCCATCATATTCTACATGGTAACCATCTGGTTGAT GAGCAGTTTTCCAAAGAGCTACTTAACCTTCAGGACATTTCATATGCTGTGCCCTCCACC CAGAGCACTCTTCTTGCCCACAGCAGGAATTTTTAGTTAAATTGGATCTTAAATTGAGAT GGACAAGACAGAGTCAAGAAATCACAACAAGATACTAGAAAATATATTTCATAAGTGTAT AGCTTAAAATAACATTCTGCGGCATGACTTAGAAATTAAGATGCAGAGCTACCAGCTGGA CTGTTTGGTGACCAACCTTCCCTCAATCCAACTCACCAGGAATATAAATCCTGGCATTTT CTGTTCAGTAAGAGTCTTCAATGCACTACAATATCAACTAAAGGCTGGGAAATAAAATAC CTGATTTCAGGGCTCCGTTAACAAAAAGGGGAATCATTTAACGTATTTAAACTATTTTCA CCATTCAAACAAAATTACTGTTTAACCCAAATGCTTAAAACAAATTTTTAAAGAGAACAA TCTAGGAAGAAAGTAATTTACCCAGACCTTTCTCAAGTGCATAGGGTAATTTTTCACACA GTGTCTTCCGTAAATTGTTAAAATGTGGGTGGGGTGAGGGGTAGAGGTTTAGCTTCAGGA GTCAGTGACTGAATGGTATTTAAAGCTTTGGTCCTGAGGAAGGTGACCTAAAGAGCCAGT GTGGTCAGAATAGAGAGGAGAGCCAAGAAGAAAGGCTGGTGTTGAGATCAGGAGAAAAAA ATCAGCAAAGACAACTCTTTGAAATATCCAGAATGGCTAAGCTACTTGAAAGGAAACAAA CTGACCAGTCAGTCCAACGATTCCATCTGCCTGTTATACTTCTACTAGGAATTAATAAAC TATTATTCTAATAAATCTGCTTTATTAATCACTGTATACATATTTCAAAGGAAAACACCT AGCATATTATATACCCTCAAATATTAATTGGTACTCAGAGGAATATTGACTCCCTTTTAA GTGCTAATCTGGTATCAACTGTATCCAGGTATCTTCAAAAGATCAGTATGTCTTCCAATC CCTCCACTCTAGCTACTCCTTGGCAAGACTCCAGCTGAATTTCCCAGTTATAGGTGGAAC CAGTTATGCCTGGTGGCTTTTGTAGCAAGAGTCCTGGGCCACTACTAACAGTTCACTTCC TCTACCCTTCATTCCATTCCAACATTGTTGAAATTTGGCCACATTTAGTCTTCCAAGATA CCTTAGGACCAGATACCCTACAATAATACCTATGAGCTCACACACTTTAAGATACTCAGT GGCCGCTCACAGCCACACACCCCTTTACAGGTGCTCCACGTGGCAGCCATCTATACTGAA TAGCGTAAAACTATTAATAGATGTGGGTGGAAAAGGTTTTGGTTTGGAGACAGATTTTCT ATGAAGACGCAATTCAGCATCCTAGTTAAGAACGCAGCTGTCAAGTCAGAAGAACTAGGG ATGCAAACCCAACTCTCCTACTGATTAGATGTATGAAATGGTGAAATCTCAACTCACTGA ACCTGAAGTTCCTCATCAATGAGAATAGGATAATAAAAATCTATTTTTCTTTCTTTCTTT TTTTTTTTTTGGAGACAGGGTCTCACTCTTATCGCCTAGGATAGAGTGCTGTGGTGTGAT CTTGGCTCACTGCAGTCTCAATCTCCTGGGCTCATGCAATCCTCCCACCTCAGCTTCTCA AATAGCTGGGACTACAGGTAGCACCTGTAGCACCTGTTAAAGTTGTGTTGTTAAAATTGT GATTGCTACTGTTTGTGTGAGGATTTAGGAGCCTATGGGCAAATTTATCTGTATACCAAT CCTCCCTCCTCCACACCAACATAATACAAAGGCTGGTGGCCCCAGAGAACAGCACTTCTT GGGTTTACAATATACCAGGACCTGTAGTCCCAGCTAATTTTTTTAATTTTTTGGTAGAGA CGTGGTTTTTCCATGTTGTCCAGGCTGGTCTCAAACTCTTGCACTCAAGTGATCCATCCA CCTCAGGCTTCCAAAGGGCTAGGATTACAGGTGTGAGCCACCATGCCAGGCCGAAAATCT ATTTCATTCGGTTGCCGTGAAAATTAACTTTTCTATGTTTGCAAATCATTCAGTATATAG TAAATGTTTCAGAACTGGTTGTTAGAATTGTGACTACTATTGTTTGTGTGAAGATTCAGG ATCCTATGGGCAGGTGGACCCAGAGAATAGTACTTCTTGGGTTTACAACATACCAGGGTG AGGACAGGAGAGGTGCCAAGAGGGAAGGGGAGCTGATGGCGCCAGAAGATTTGGAAGCCC AGGATCTAAAAGCAGACGTCCTTTTGTTGTTCTGTGCCACCCACTATTGATTCAGAGAAA GAAACATGGGTCTCCTGCCTGACACTGTACCACATGAGGACGTTCTTCCAATGGCTGGAA GAAAGGAAGGGGCAAAAGGTTACCTGGAGTTTAGTTACCCTCAGTAATTAATTACTAAGG GGTCCCCATGCCACTTTTGAGTCCATACTTGCTAGTTCTCTATCAGTTCAGCCAGCCATA ATGCTTCTGATGCTGATGTAAAAGGAAAATCTGTTCACTGATGAAAACTGAGTGTAGAGT TCAAATCCTGGCTCCAACACCTCTTAGCTGCATAACCTTGGATAGCTTACCTGGTCACTC CGGTCCTTTTTTCCTGCATTTGTAAAACCAGGTATGCACATATAACTCATATAGTTGCTA TTAAGAATAAATATGACATTCAAAAGCACCAGTCTAATAATGTGTGTTCCCTTTACCTTT ACTCAATAATTATCGGCCCCTCTTCCTGGACCACTTCAGACATTTTCTTAGGATACCACT TAGGCAAACGGTGACAGCCTGTGATTGACCCTCTGAGAGGTTCCAGGAATAGCAGCAAGG ACTGCTACCACCACCCATGGGCCATATTCCATGTTTAGCTGTCTGGTGGATGCCAACCCC CCTCAAATTCAGAATCAAAACTGAATTTTCCTTCTTCCCTCCAAAACCAGATATTCTTTC CTCTTTGTGTTCCTCCTGGTCTCTTATTAACACTACCACCACTTTCTCCAGTTGCCCAGG CTTAAAACCAATTACAAACATTTTATTTCTTTGACCCACCCACTCACTGAGCCAGAGAAA CATGAATCCTTCCCTCAGTTTCCTTTGGCTCCATTTCTTCTTTCCATTCCTCCCACCACT GGACCTTAGGTCTAGACCACACCTGCTCCTCAATTCCAAATGGAGCCCTACAGAAACTAT CTCGATTTCATCAAGTTCAAGAGTCCAGGAACTTGATGGTACCGCTGATGCTAAAAAAAA AAAAAAACAGAAAAGAAAAGAAAAAAATTGTTGGCACATTTGAGGGAAGCTGGGCAAGGA GGGGGAGGATATTCAAAACACCCCAAGGAAGAATAACAGGGTCACTTTTTCTTTAAAGGA TGAAGTTTATATTGTAGCAAGTCAGAATAAGAAGAAGATACAGAGGACTAGAAGTCACGG TTGAAATTCAGATCAGAAATGTCATCCAAATATAGAAAATAACAAATAATAAAAACCATT TTTCCATATACAGTATTCTGTAGAGTCAGTGACATGGCAGACACGGTGATTCTAATCCAC GGCCACAGCTTAGGAGCAGTAGTTATTTCATTTATCAATTAATTTTCTTTAGTGCCTGGC ATATCTATTTCAAAACCATTAAGTAATTGTAGCTGTTAACTGAATGCTTACTATGTGCCG GGTACTGTGCTGCATTATCTACATATTCTCTGCCTTGGTCCTTACCCAACCCTATGAGGG GCACTGCAATCATTCAAAGATCAGAACTGATAGTATAGAGATGGGGGAGAGACATGTCCC TGGGCTCACCTTTACAAGAGGAAAATGGTTTGCCCCAATAAGAAAACATTCATATAGTAC CTAAAGTTTCCAATGTCTTAATGCTCATCATCTCATTTGAGTCACACAATAATTCTCTGA ACTAGGCATGACATTAATTATTATCTCTGACTTACAATTAAGAAAAGCTCCAAGTCATGC AGGCCACTGTCTTCTTGCCTTCAAACATCTCTGCATGTTTCTTTCTAGAGCTGGTGGAAA AAGGACCATATCTGTGCCCACTTGTGAAGGGAGTAAAGGAGTATCCTTGGCATTACTAAT GTCTCCTTTCTGATCCGAGAGAGAGTGTGTCATGAAGACACTCAGGCAGCTCCAAGTGGA GGTCCACACAGTAGGAACTGAGGCCTCCTGCCAGCAACTAGGTGCAGGAGCCGTGTTGAA AGTGGATCCGTTAGTCCATTCAGCCTCCAAATGACGACAGCCCCAACTGTCAACTTGACC ACAGTCTCACGAGAGGCCCTGAGCCACACCATCCAGATGAGCTGCTCCAAGACTCCTGAC TTGTTCCTGACATAATAAATATTTGTTGCCTTAAGCCCCTTAATGATGAGGTAATTTGTT ACACAGCGATAGATAACTAATGCCAATCCAAACCCTGAGATATATGAAGCCTGAGGGTTT CAACATGAAGAAGCTGACAAGAACTGGGATCCCAAGAGAGTTCATGAATTCCCTTCCAGG AGACGTACGCAAGTGCAGATGCTGAACTGCCAGGCAGAGGTATTACAGAAGGGATGCACA CACAGGATGGAAACTTGCATAGATATCCCTTCAGGTTACTTCCAACCACAAGACCCAGTG AATTTAATTGTAAACGTCTCCCTAGTCTAGATGTACACACGGTTGTTGCCAGAATTGAAT AGCTAACAAGCTGACTAAAATCTATCCAAAGCCTCCTTATTTAGAACATTTGAAATAATT TATTATTTTTGATAGAGAAAAGTGGTCACACAGGGAGTTTCATTTTCACCTCCCACTTCC CAAGACAACTGGCTCACTTCCCCAGCCAACCTCAACAAAGTTTTATCTCGGTGAACTACC TGAGTCTTCTCACCCTACCTGCCCCAGCCTACCTGCCCCCCAGGAGAGTTAGAGCTCTGA CAAAGAGGAAGCCTGAATATACCCTTACTCTTAAGGCACTGGTTTTCCAACATTTCTGAT AATTACTACTTAACAAGCACACTGTAAACTAGTTCAACCATTGTGGAAATCAGTGTGGCG ATTCCTCAGGGATCTAGAACTGGAAATACCATTTGACCCAGCCATCCCATTACTGGGTAT ATACCCAAAGGACTATAAATCATGCTGCTATAAAGACACATGCACACGTATGTTTATTGC GGCATTATTCACAATAGTAAAGACTTGGAACCAACCCAAATGTCCAACAATGATAGACTG GATTAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCATAAAAAATGATGA GTTCATGTCCTTTGTAGGGACATGGATGAAATTGGAAATCATCATTCTCAGTAAACTATC ACAAGAACAAAAAACCAAACACCGCATATTCTCACTCATAGGTGGGAAGTGAACAATGAG ATCACATGGACACAGGAAGGGGAATATCACACTCTGGGGACTGTTGTGGGGTGGGGGGAG GGGGGAGGGATAGCATTGGGAGATATACCTAATGCTAGATGACGAGTTAGTGGGTGCAGC GCACCAGCATGGCACATGTATACATATGTAACTAACCTGCACAATGTGCACATGTACCCT AAAACTTAAAGTATAATAAAAAATAAATTAATTAATTAAAAAAAAAAATTTCAGTCTTTG AGGTTAAAAAAAAAACAAGCACACTCACACACACATTTAAACAAAAGTTGACATTTAAGA AAACAATGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCGAGAC GGGTGGATCATAAGGTCAGGAAATCGAGACCATCCTGGCTAACACGGTGAAACCCCATCT CTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACT CAGGAGGCTGAGGCAGGAGAATGGCAGGAACCCGGGAAGCAGAGCTTGCAGTGAGCTGAG ATCACGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCTGTCTCAAAAAAAAAAAA AAAAAAAAAAAAAAAAGAAAACAGTGCTCACCATTAGAACATGAAGGACATTTTGGTCTC ATACTGTTCTACTACTTTGTTCTTCTTAAAAAAACACTTGGTCAAAATCCACAACCCAGT AAAAGGTCCCAAGAAACAGTATGGAGAATATATCCGAAGACATACTTCTGAACACTCAAC AGCTCCTAAAATCCTCCTAGGTAGAGACAAAGGCAAAAAACTGAAATAATAAATCCCCCT TCACCCCAATCATGTGTAAATACTTAGTTCCACTTCACCCACATCCATAAAATACACAAT AAATGCTGGGGCTTTCATCTAATCAAGAACAACCTCAGGCAGTTTCTATTCAAATATAAA TAATTATCCAGGCCCCAAAATTCTTCTCCTAGTTCCACAGGTAATGACTGGAAAATCTAC AAACAACTTCAGCTAAAACTCCCTTATCACTCTTAACAAGTATGGCTCAAAGACAAAATT TCAATCTTTTCCAATTTTTTTTAAAGTAGGCAGGCAGCAAAATAAAACATCAGCAAAAGC TAAATGTGCTTGGATAAAGCACAATTAAATACATGTTTGTATTTTTCCAAAATGGACCAC AGGTTGCTATTAAAAAGAGTAATAAAATCAATCTATAGAAACTAAATAGATAAGTGTTTG CCTGCGGGCACGGGATGTGGAGTGGCTGTAAATAGACACAGGGTGATGAAAATATTCTAA AATTAGATTGTGGTGATCACTGCACAACTCTGTAAGTTTACTAGAAATCACTGAATTGTA CATTTAAAACAAGTGAATTTTAAGGTAAACTATATGGTGATTATTTATGGCAAATTATAT ATCAATAAAGCTTTTTTCTTAAAAAATGGAAACTATATGTTAGATTTTTTTTTTAATATC CAAGATACGTGTCAGTTAAAACAAGCAAAGTACAGAATAATGTGTATGACATGTTCCCAT TTGAACTTTTAAAGTGATTGTATACATTACCTGCCTAGACATTTCTGGAAGGACACCCAG AGGCTGATCATAACAGCCGCTCTGGGAGAAATGGGTCTAGGCTAAGAGAGTTTGAGTTTT AATTGCATACTGTTTGGATTCATTTGCTTTGAACATGTATTATTTTTCATAAGTATGAAA ATAAGATGGGTGGAAGCCCTCAGGAGTAGGACTCTTACAGCAGTACCAAGTTTATAACGG TGCTAGTTCATATTGTTCTTTGAGAAGGGGATAGTTTGGTCCTTCAGAATTTAAATATTT CAGCAAGGTAGGGTGGCCTGTAATTCCAGCACTTTGGGAGGCCAAGGCGGGAGGATCACT TGAGCCCACGAGTTCAATGCTGCAGTGAGTCATGATTGTGCTACTGCACTCCAGCCTGAG CGACAGAATGAGACCCCGTCTCTTTTCTTTTTTTTTTCTTTTTTTTGAGACAGAGTTTCA CTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGGCTCACTGCAACCTCGCCTCC CAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTTGCTGGGATTACAGACATGCGCC ACCACGCCCGGCTAATTTTGTATTTTTTGTAGAGATGGGGTTTCTCCATGTTGGTCAGGC TGGTGGTGAACTCCCGACCTCAGGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGAGAT AACAGGCATGAGCCACCGCGCCTGACCATGAGACCCTGTCTCTAATTATTTCTCAGTAGA AGTCTGCGTTAAAAGGTACCTGTGTTTGACAATAAGAGGCCAAGTGACAGAATCTTCCAA CTGAAATCTGATTTCATAAAATCCAAGAGGAAGAGAATTTGAATGCCCTCTTAGGAGGAA AATGGGGTTCATATCATTTAGTCGTCTCCTTCGGCAGGTGCTGGAACACAACTCAAAGTG GCTTATGGTTTGCAATTATAAATCTGGGAAGAGATTAGATACATTATATCTGAGTACAGG ACTATATGCATCTAGGGAGTTGAAAACATAGTCCTCATAGAGCTTTATCAAAAAGAAAAA GAATATGCAAATAAAAAACTAAAACTGAATCCAAAAAGGTAGCTGAACACCACACTCTCA AATGTTGTAACCAGACTTTTGACAACTGCTCAGATCCAGGCCTGGGTTCTACCATCTTGC CTCAGCTCATTTTTGGCTTTGGTTCCTAATTGAGCTCTTCACCTCGCTATTTAAGGACAC TGGCTCTCTGAACATTGAGAACCTGTGGCTCACCGCATCCTCCCCTCCCCACCTTAGGCT CATCCTGTCATCAGACGGCTTCCTGATTTACAAGGCCAAGGTAACCAAAATTTGGACCAT AAAATATTAGTATTCTCAACTTTCAAACACGAGCCAACCAGATGACCTGTTTCCAGGATC ATGGCAGCCCCTCCGACCCAGAGCCTCTCCTGCTAGTGGGGTCTTCTTCCTCCAGTGCCT CCACTGACAAAGGAGCCACCGTCTCAGCCACCCCATGAGTCTGCCTCCCGTGAGATTTCT ACAACTGACACTGCAGCCCCCACTTCCACTCTCATCTATTTGTGCCACTTGGATTATTTC AACTATATTATTCAACACTCAGCCACCTGTATTTACTGAATGGCTGCTCTGCCTAAGACA CTGGCAGGGAGGGGAGAAAATAAGGGTATTTTTACAGTAACAATTAGGACAGTGTTTTGT TTCTAATAGCAGCTTGAGAAATAATTCGCATACTATAAAATCCACTATTTTTTTATAAAG AGTATGGTTCACTGGTTTTTAGTATATTCACAGAGTTATGCAAACATCACCGCAATCTAA TTTTCATACCCCAAAAAGAAACCCACATCCATCAGCAGCCTAGGCTAGTATTTTTATGAA AAAAAAAATTTTTTCAGAGTTTCAGACTTGCAAACTTTTAAAACATTTAAAATTATAAAC TGTCCAGGTTATCCAAAGACTGTACAGTATATGGTCCAGATTAATACAGTTAATAATTAC CCACTCTGGGGCATATGCAACTTCAAGGGCAGAGGTAAAGATTTGCCTTGGGGAAAAATT CAGCACAACCATGAAAATAACAAGTAGCAATAAACGGGGGGTGGGGGTGAGGGCGGGGAA GGGGTTGCATTTGGATAGCGCCTCCCAATGCACTTGAACACTATAGCTAACAATACTGCA TTATACACTTAAAAATTTGTTAAGAGGTTAGATCTCATGTTAAGTGTATTATCAAAATCA AATAAAATACAACGGCGTTTTTCAATCCTCCTAACCATCTTGACAGGAATACAAGACATT TACAAATGGGGAGCCTGATGTTCGGGGGATGGATGCCTGACTCCCAGTCACCCAGCTAGG GGACCCCACCCGGCTCTTCTGATTATCTGGCAGAAGTGAGCAAAACAGCTCAATCCAGCA GGCTCCATGTTAGCAGTAAGCAACTCTAATTTCATATCTGACTGAAAAAAGAAAAGAAGC CTATTTATGCTCTCAACATAATAAAGCAGCCTTTGTTTTATGCTAAGGCCCTGGTGATTT TTTCAGCACCAGTCCAGCTGTGACACACAGACGCTGGTTCGATGCCTGCATAAATGCTTT CTCTTTGTTTAGTGGTGAGAACGTGAGACCTCACTAAGGCCCAAGTCCTGGGTTCTCCTG ATGTCAACCCCACAAGTGAGTAGTGGAGCCTCACTGGCAAGGAGACCTACCTGTGCCTTT CCCAAATGCCTGGGAAGGTAGGTTAGAGTTAGAATCTTTTAATTAAAATGAGGTAAAATT CTAATTACTCCACAGTTGTCTCCAGAATAACATCATTTCCAACTCATCAAGTCTTATTAG AACCGGAACCACTGGGAACACCAGCTCCACCTTGTTAACTAAAGAAAACAGCTCGCTTTT TCCAGGAACATTAACTCTTTTTTCAGACATAAAGTAGTATTTAATGGTTTTGCTTATTAG TCTCCAAGCCATTAATGACCTGAAAGAGATTAAACAACTTTTGAAAAGTAATCCATTGTA AGTAACAACGGTTAAGGCTTCCTTGTAGCTACGAAAAACACCCAGAGTGCAGGACACTCA CTTAAAATTAACACTGACTTGGATGCACACCACACACAAACAAATACAACTCCCACATGT AATCTATTTTTATATGAATTGGTTGAAGGTGGTAACAAATTCTAAACAATATGATGTACG TAAAAGGGTTAGCTGCACCGCACTCTAGGAAACTATTGCACCAGCTTCTACTCCTGCACC ACTTAGCAACAGGAAAACGATGGGGAAACACTACCAAACTAACGAGTGGGTCACCTCAGA TTTGATTTAACCCTAAACTCAACAATCTCAGGAAGTTCTGTCATACCGGCAGGAAGAACA GACCAAGAGGAGCATTTTCAGGGGCAATACAACTCGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTAGAAAGAGTATCAATCATGACATTATGAGGCATGGATGAACCACACCACCC AGTGTTAGCAACACGTGGATCATCTGTGGCTCTGTGCATGTGTCACTTTCCACAGTTACA TACAAAATGTAACTCCACTACTAGACTAAGCTGTTTGAAGGTTAATTCCACATCACATTC ATACTCCATGCAACTCACGACACATCAGCCTCACCTCCCAGACATCACTCCTAATCCCCT AAATTCCAGCTACAGACGCCCTGTACCTTTCCTTACTCATTACCCAGTGGGTCATCTCTA TGACCCCCAATATCACTGGCATTCACACCTCTGGGTAGGCCCCTTCCACGTGGCACCAGG GTTGGTCTGTGTGACCAACAGAATAATACAGCTCTTGGGTTCTCTTTCTCTTGCATCATT TGCTCTGAGGGAAGCCACGTTGTGAACAGCCTTATGGAGAGGTCCCTGGGGTGAGGAACT GGCACCTGCTGTCAATGACCACCCAAGTAAGCTTGGAAGCAGATCCTCCAGCCCTGAGAT GACTGATGCCCCAGCCAACAACTCTACTGCGACCTCATGGAAGACCCAGAGCCAGAACCA CTTTCTTGGCCAGCCCCAGATTTCTGACCTGCAGAAACTGTGAGATATAAATGTGGCTGG GCGCGGGGGCTCACGCCTGTAATGCCAGCACTTTGGGAGGCTGAGGTGGGCAGAACACAA GGTCAGGAGATCGAGACCATCCTGGCCAACATGGTGAAATCCCGTCTCTACTAAAAATAC AAAAATTAGCTGGGCATGGTGGTGCGGGCCTGTTGTCCCAGCTACTTGGGAAGCTGAGGC AGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCA CTCCAGCCTGGGCGACAGAGCCAGACTCTGGCTCAAAAAAACAATAAAAATAAAAATAAA AAAATATTTTATTAAGCTGCTAAGTTTTGGGATAATATGTAGCAATAGATACTAAGATAA TAGCCACACCATCTTCATCTGGAATGTTCTTCCCTAGGTCTATCAAAATTCTGAAAAGTT GAGATCCAAGGAAAGTGGCTTGTCTTTTATGAAAATGCTTTGGAATCTCACTCACCAGCA TCACTTCTTTCTCTTAAATGGCATGGGTCAGTCTCTAACAGTGACGTTATTCTGTCATGT GTTGCAATTAAGGCTCATATGCCTGCATTCCATACTAACCATGAGCTCCCAAAGGCACAA ATCGGGTCTGTATCTTCTCATGGAGAGCAGTTAGCCTAGTCATATCAGAGATTCTCATCT ACCCCGTACCTGTGTACAGGAAAAACTGGGAAGTGATCCTGTTGGACATTAAATTAAGGT TGGGCTGGTCCACAGTAATAAAGGCTTAACTGTGAAGACGCTGTCTCTAGTCAAGGACCA CAACTGGAAAATAAAGCAGGTCAGCAAAAAGGGGAAGACAAAAATTACAATCAGGCTGGG TACAGTGGCTCATGCCTATAATCCCTTTGGATTACTTTGGGAGGCCAAGAGTTCGAGACC AGCCTGAAGTACAAAAATGAGCCAGGTGTTGTGCCGCACAACTGTAGTCCCAGCTACTCA GGAGGCTGAGGCACAAGAATTGCTTGAACCCAGGAGGTGGAGGTTGAAGTGAGTGGAGAT CATGTCACTGTACTCCACCCTGGGCAACGGAGTGAGGCTCTGTCACAAAAAGAAAGCACA ATCAGACTGGTCCTGGGCAGAACTCAACCTTCCCTTCCTTACCCCTACACTCTCCCTTAC AGTCCCATTAAAAGAGAATAGGGAAGGAGGAATAATCTATAGAAACTCTGACTTGACGAC ACTGCTGACTGTTGTGCCCAGAATCCAGCAAGAGCTAGGACCTCGCACACACATTCATGT ATTTCCTCATGTGCATGTAAGGATGCACACACTCAGGGGAAGTGAGGTAAAAGTAGGTAG TTCACCAATCAACAGAGCAACACCCTCCAAATCAGCTGCCATGTCTTAAGTATCTGGTGA CCATGGTCACAAAGCATGAACTTGGGAATTAAATAGATGGGGTCTGGATCTTGACTCCAC TATGAACCATATGAACTAGGAGGAAAGTACCTACTTCATGGACTCTCACATCTCCCATCT GAAAATTACTACAAATTATTAAGGCAACTGCTGAAAAGATGAAATATGATCAATCTAGGA GTTTGTATATACCACCAAGAACAATGCTTGTCAAATCACTCACTTCTTTTCCCCTCTCTG GAGCCAGGCTTCGAGAAGTTGTATCCAGAATGAGAAGGTCTAAACCCTAACATAAGGACC CAAAGTCAAGTCATCTTTATTTGCCTTTACTGCTACAAATCCCGAATGAGGGTCCAGGGT TGAAAACATAACCCTCAACTTCACTGATAGACTTACGTATAACCCCAATTAAAAGTTTGG CTCCTTTGGGACATACATTTCTCTTTGACCAAAACTCATTAAAACTTGGCAGGAAGCCAC CCACAGTGAGCTAATTATACACAGCACCACCCTATATATTAATAGCTTACTGTAGCTAAC TCATATGCTAGCATCCACCACCTGTCTACACCTTCCTTACGTGCAGGAGCCATGGATTCA TTTCTCTCTTTTTTTAAGCTTCATAGTTTAACAAAATGTCCATCATTTTAAAAGCGACCA ACTGATCAATCAAAAATTATCATTTCTAGAACTTAGTATCACATAACCCTAACTTAGGGA ACTAAGAAAGTAGAAACAATGAAAAACTTACTAATGATTTGATAGTTCCATTGCAACAGG AAGCTAAACATTTATTAAGATTTTAGTACATTCCACCATATTAAACATCAAAGCAGACAA ATATGCAAAACACTTTACAGAAAAATGCCATTTATGTTCTTGTAATGTTCATGAAACATA AAAATTAACATTTTAAACAATCATAAAAGTCACATTAGTTTGTTTGTTGATGAATCTGTA AGGTGAAATCCATGTAAAATACTCTAAAATTTAAATTTTTTCCCCAAAGGATACCTCTTA TACAACAAAAATTTTAATTTTATATGACAAATTCTGTAATCAGCTTCTAAAAATGTTGAA GGTATAATCAGAATCAACCAGAACTTTCACCTTCTTCAAATGAAAGTAATCTCTGTCAGG AAAAATTTGTGTAATATTTTGTAATATTACATATATCATAATATTTTGTTCTTTTTCCTA CTATGAAGAATATCACAATATTCCAATTAGTACATAAATTACATCTTAATATTACCAACA TACAAGGCTAGGATTTTGCAATTAGAAGCCAAATTCTGACAAAATAAAACAGTGCCTTAA AAAACACTGAACAATTAAAAATGTTACATATATTAGAATATGGGACAGCCCATAAAAAAA CTAATCAATACTCATCAGAACCAACTAGGCACTTCCAGCTGAGGTTAAATGACCTTTTGC TCCTGCTCCTGTTCCTGAGGGCCTGTCTTTGTCACACAGCTGAGCCAGCACCTGCCTCTC CATAGCAACTGCAGCATGCCCTTCAGCGCTATGAAAGATAACAGATAGGTGCCTCCTCTT ACATTAAATATTTATTAGGTTTCTGAATAGTGGTCTTCCCAGGGAAGTTCATGGGAGGCA CACACAACTCACAGCCACCCATCCCTCCTTCAAAAACACCTTTTCTATCAGAGTCACTGA AATACACCCAGAAAGGGAGACCACAACCAGTTCTTTGGGGCAGACAGGTGTTGGACTGTC TCCTTGACATGGCTTTTTGTGTGCATTTTTTACATGGTATTCGGTGTGCATTCTAACCAA ACTCAAGGATTGTCTAAATTTGTAGGTCATCTCATTCCCTGTAGCACCTTGTCCAGTAAG TTATAACAACCAAAAAAAAAAACCTAATAAGCATAGTATCTATTCAAAGCCTAATAAGCC CTTATATCCTGGTTGTGTGGAAAGGATTAAGATTATAATGAGTTACTCTGTGGGTTATTT TTTAATTCATTTCTACACACCACATGAGGTTCAAAATGAGCAACTAACTCAGGCTCAGCT GAAGAACTCCTGGAGGGTCACTCTTTATCTGGGAAGCACTGGTGTTAAAAACTGGTGCAA ATTTTGTTGCCACTTAGTAGAGTATTTTCACATCCCAAAGCAGAAGCACAGAAGTAGGTA AGAGATATCAAAGTTTCCTTACAAGAGAAAGGATTTCTTTGCTTCACCCTGCCCTGCATG AACAGCTAAGTGAAAAGCAGATTCTCCCACAAGGCTCAAAGATATAACAGTAATCTTGTT TAATCCTAGCATGTGGCCAGAAGTGATGAATCTATGTGAAGATTTTGATGGCAGGTGATC TTTGAGCGGGCATGGCAGTTGCACCACAAAAGGTCGAACACATTTTCACGGGAAAGTTGC CTATGTGCTACTGAAGAAGCTAGACTATGAAGGAGCAGCCGAAATGCAAGAACACCTTCC CCTACTTCTCTGTATCCAGGACTCAGCTCAGTGCTGGGCACATAGCAGGTGCTCCGGGAA TGGGAATGGGTGACTGTAGGAATCATAAGAATTTTTCTTCTTTCAGGAGTACTGCACATT CCGGGCCCACTTCATGCCCCAGAAGTTACTATTAGACAGGAACATCATCAGCAGTATGAC AAACTAATAGGGAACTAATTAGGAATATGTAATATAGACATCAAATCTTTTCTTCAAGAA ATGACTCAGTTTCTCTACAACCTAGGGCAACTCTAGACAATAGCAGCATTTTCACTTGTC CGAGATGAAAGGAGGAGGGAAAAAACCCACAGTGTTCCTGAAACTAAATTTAAAAGTAAT GCCCTTTATTCTGAGATAATGTTTTTCCTGATTTTTTGGAAGGGGAGGAGGAGTGTTAAA AATCTCATATCTATAAAAACATGGTGGCTTTTTGTTAGTTGATTTTAATAACTTGGCAAA ACAAGGAGTAGACAACTCAGTGTGAGCTCTCCCCCACCCAATTTTAATTTATGAATTCCA AAAAATTAAAAAGGGTAATGCTAGGACGTAACACCCACTTGCCCTGCCTACAGCCCAACT CACCTAACACACATCACTGTGCAGAACAGAAACAGGACAAACTGGTTTAGAAGGCAGAGG GGACAAAGAATGCTGTATTTGGCTATACATACACGGAATCTAACATGAGGTAAGAACATC CAGATTGGAAAAGTCTAGCACTGAAGTCGTGCAAAAAAATATACTTGGATGTATAGCCCC TGGAAGTTCACCTAAGTGAGCCATTGTTGCTAAGGGCAATTCTTATTTACCAGGTGTGCT GGTAGGGGAAAAAAACAGTTGACTATCACTGCTTTTAGTTAGTCTACAAAAAGACTTAGA AAAACTGGCTAGCAGCCCAAAGCCCATTTCAGGTTCAGTTTATAAAGGGTCTAGTAAGCA CATTTATGATTTTCCTAGCAACTCCAGGTTAGCCTCAGCTTAGGCAGAGAATAAAACAAA CTACCTAAGGCCGGGCATTAATGTGGTGAGCATCATAGAGTGATGGTCCCATTATCTATT AAAACAAAAATAGAACAAAAAGTGCACATGTTCATCAATTTCACTTCTCCATATTACCCT AGACAAACATAGCTGCATAAAGGAGGAATAAACAAAGATGTTCAATGCAGGATTTATTTA TAATAGTTAACAAAAAATACTGGAAAGAATCAAGTATCCATTAATAGAATTAAGGCACAT TTATATGTGGGTACACTATGTAGCAGTTAAAAATAATGAAGTGATCAATATGTACTAGCA CAGAAAGTGCTCCATGACATGGAGCTGATGAAAAATACAGAAACACAAGCATGACAGCAT TTGATTTTCTAAAAGGCACACACAAAAAAATCCCATGCTATATAGCATTCCCAAATGTGG TCCCTGAACCAGCAGTATCAGCATCACCTGTGAACTTGCTAAAAATGCAAATTCTCAGGC CTCACCGCAGACCTACTGAACCAGAACTCTGTGGGTGGGGTCAGCAGTCTGTTTTAACAA GCCCTCTGAGGGTGTGAGGTCTTGTTTTAACAAGCTTGAGAACCACTGGCCTACATGGGC AGGCATAAAAATCACTAAGAAAAGGTTGGCCAGACTTGCACCAGATGAAGTCTCTGCACA ACTCTCTTTATCTACACTCTTGCCTATCTTTATCTATACTCTTGTGTTCATGTATTGCTC CTGGAAGTTAAAAGTACCATTTTTAAGATACTGCAGGTGCTAGGGAGGAGCCTGGGGAAA TGGTTAACCATGCATCTCAGCAAAAATAAGGGAGACCTCGCTGACGGGATAGGAGAATGA GGTTCCGGGAACTAAGAGCTACTGAAACACTGCCGATCACAAAAAGCACAAAAAACCACG TCCAATCAGAATTTTACTCCAAAACTCTCAACAGAGTTCAGCTGGTCTTACTGGTGACTC CGGTGGAGAGAGTACATGACAAACAGTCAACACTAGTAGGAAGGACAGCTAGCTACCAAA GGATGAAAAAGAATGAACAATGAAGACCTTGTTTGAGAAAGCTAAACTATTTGCATAGTC TTTTGCTGTCCTGTTTTGTTGATTCTTTAGCACTACATGTGGCAGCGGCCACCCCAGCTC CCAGCCCCCACCATCATCCTTACATTTGCAGGGGTTGTTGAGCAGGGCAGCAGGGCAAAG GCGACAAAAAAGGGAGCTCTGAGACCTATGGAACAAACCTTAGTGAGGCCCTCTAGCCAC TACCATTCTAATCCCTAATCAAGCCTCTTCAAGACAGTGGGGCCTGGAAAATGTGCACAC ACACATACATACACACACACACGCACACACACACACACACCCCCCACACCCCCTGTACTT TATTTCCTACTAACTTCATAATCAGAAGTGAAATCAACCATTACTGCCAATGCTTGTAAA GATAAAATAAACGCCACAAGAGTAGTCAGGAACTCACTTTAAAATAAGGTTTAGAGACAT CTATAAATCTAAAAATAAGATAACTATACTCAATTTTCATTTGAGAGACTGCCTTAAGAG GTAACCTTATTAATCTCCCTACTATTGCTGTAAGTCAGGTTCCAAACCAGAGCTAAAAAG TAAGTGGTATTTTATTAAAACTTACAAATTTTCCACTTCTAAATTTTTTTTTTTTGAGAC AAGGTCTCATTTTGTCACCCCGGCTGGAAAACAGTGGCACAATCACAGCTCACTGAAGCT TCAACCTCCCGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGTAACTGAGATTACAA GTGCACCACCATTCCTGGCTAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTACAGAGAGAA TCTTCCTATGTGGCCCAGGCTGGTCTTAAACTCCTGGGATCAAGCAATCCTCCTGCCTCA GCCTCCCAAAATGCTGGGATTACACGCAAGAGCCACCACACCTGGCCCTAAATTGTTTTT AAGTGAGATTTTGGTGGATTTGATGTCAACAGTGTGTGGCATCACCCTTGACATAACAAC ATAAAACAACAGTTTTAAAGCCAATATCTAAAACAGCCTTTTTTTAATTCTTTAACTTTC TGACAAAAGATCAAGTAAAAGTTTTGCTCTCTGTAACAAGCACTCTTCAGATTTTGCTGA AGAGAAAATGCTAAATAAAAGCACATTCTCACTCTGGGGTTTGGGGAACATCAGTTACTC CAATTTCAAGCTTTATTCTCTTGGATTCTAGGAGGTCATCATAACCCACTTATATTTTGA TACAAGCAAAAGCCCATGCTTGAAGACTGAAGAACTACAAAGAAACAGCTGTATGCCATT CCACTTTCTGGGCCATGTTTCTCTGTTGTACAGAGAAAAATCATTTCTTTTTTTAACCTA AAAGCAAACACAGTTCTGCTCACTTCCCACTATTCAGCCTATTTTTTTCCTCCTTTAACA AGGCCAAATTTTTAGCTGTATCCATTAAAAAGCTTAAGTTATTTACACAGAGAAGATGAA GCAAAAAGTGTTGTTACAGCCTCATATAAAAGAAATATCCAATTATTAAAACAAAACCAA ACAAAAAAAAAGATTTGCCACTACATAGGTGATATAGTTTGGCTGTGTCCCCACCCGAAT TTCATCTTGAATTGCAGCTCCCATAATTCCCGTGTGTTGTGGGAGGGACCCAGTGGGAGG TAATTAAATCATGGGGGCGGATTTTTCCAATGCTGTTCTTGTGATAGTAAGTCTCATGAG ATCTGATGGTTTTATAAAGGTTTTATAAAGGCCCGTTCCCCTGCACACGCTCTCCTTGCC TGTTGCCATGTAAGACATGACTTTGCTTCTCATTCGCCTTCCACCATGATTGTGAGGCCT CCCCAGCCATGTGGAACTATGAGTCAATTAAGCCTCTTTCTTTTATAAATTACCCACTTT CCAGTATGTCTCCTCATTAGCAGTGTGAGAAAAGACTAATAAATTGGCACTGGTATAGTG AGGTGCTGCTTGTAAAGATACCCAAGAATGTGGAAGTAACTTTGGAATTGGGTAACAGGC AGAGGTTGGAAGAGTTTGGAGGGCTCAGAAGAAGACAGGAAAATGTGGGAAAGTTTGTTG AATGCCTTTAATCTAAATGCTGATAGTGATATGGACAATAAAGTCCAGGCTGACGTGGTT TCAGATGGAGGTGAGGAACTTGGGAACTGGAGCAAAGGTGACTCTTGCTGTGCTTTAGCA AACAGACTGGTGGCTTTTTGCCCTAGAGATAATGGTAGAACTTTGAACTTGAGAGAGATG ATTTGGGGTATCTGGCAGAAGAAATTTCTAAGTGGCAAAGCACTCAAGAGGAAGCAGAGT ATAAAAGTTTGGAAAATTTGCAGTAGAAAAGAAAAACCCATTTTCTAGGAAGAAAGTCAA GCTAGCTGCAGAAATTTGTATAAGTAATGAGGAGACAAACGTTAGACAAACATAAAGACA ATGGGGAAAATGTCTCCTGGGAATGTCAAGAGACTTTCAAGGCAGCCCCTCCCATCACAG GCCTGGAGGCCTAGGAGGGAGAAATGGTTTCCTGGGCCAGGTCCAGGGCCCTCCTGCTGT GTGCAGCCTAGGGACTTGGTGTCCTGTGTCCCAGCTTCTCCAGTCATGGCTAAAAGGGGC CAAGGTACAGCTCCAACTGTGGCTTCAGAGGGTGCAAGCCCCAAGCCTTGGCAGCTTCCA CCTGGTGTTGAGCCTGTGGGTATGCAGAAGTCAAGAATTGTGATTTGGGAACCTCCGCCT AGATTTCAGAGGATGTGTGGAAACGCCTGGATGTCCAGGCAGAAGTTAGCTGCAGAGGCA GGGCTGTCATGGAGAACCTCTGCTAGGGCAGTGCAGGAGCGAAATGTGGGTATGGAGCCC CTACCAGAGTCCCCACTGGGACACTGCCTAGTGGAGCTGTGAGAAGAGGGCCATCATCCT CCAGATCCCAAAATGGCAGATCCACCAATAGCTTGCACTGTGTACCTGGAAAAGCCACAG ACACTCAACGCCAGCCCGTGAAAGCAGCTGGGAGGGAAGCTGTACCTGCAAAGCCACAGG GGTGGAGCTGCCCAAGACCATGGGAACCCACCTCTTGCATCAGCGTGACCTGGATGTGAG ACATGGAGATCATTTTGTAGCTTTAAGATCTGACTGCCCCACTGGATTTCGGACTTGCAT GGAGCCTGTAGCCCCTCCATATTGGCCAATTTCTCCCATTTGGAATGGCTGTATTTACCC AATGCCTGTACCTTCATTGTATCTAGGAAGTAACTAACTTGCTTTTGATTTTACAGGCTC ATAGGTGGAAAGGACTTGCCTTGTCTCAGATGAGACTTTAGACCGTGGACTTTTGAGTTA ATGATGAAATGAGTTAAGACTTTGGGGGACTGTTGGGAAGCCATTATTGGCTTTGCAATG TGAGGACATGAGATTTGGGAGGTGCCAGGGGAAGAAAGGTATGGTTTGGCTGTGTCCCCA CCCAAATCTCATCTTGAATTGTAGCTCCCATAATTCCCATGTGTCGTGGGAGGGACCTGG TGGGAGGTAACTGAATCACGGGGGCAGGTCTTTCTCGTGCTGTTCTTGTGATGGTGAATA AGTTTCATGAAATCTGATGGTTTTATAAAGGGAAGTTCTCCTGCATATGCTCTCTCTTGC CTGTCACCATGTAAGACATGACTTAGCTCCTCATTCACCTTCTGCCATGATTGTGAGGCC TCCCCAGCCATGTGAAGTTGTAAGTCAATTAAACCTCTTGCCTTTATACATTACCCTGTC TCAGGCATGTCTTTATTAGCAATGTGAGAACAGACTATTACAATGGGAAAGAGAAATAAC AAAAGTATATTTTACCTCTAAAAAGAATAGGCTTAAAACTTGAAGAAACAGCCGAAGTGA TTGTTAAAGTATATTAAACAAAAATTATGGGAGGCCACTGTTTTTGGACTAAGCTCCTGC ACTAGGACCCAAAAGCCAGACCACACCAAAGTGAGTCACTCATGCTTACTGCCACATAAT CATATTGAAACTTTAAAGAAGCAGTAGATCCCCAAAAAAAGATCAGTTTTTTCTGGAAAC AGGAGATTCCAAACTACCAGAATCAGCATAATAAGAAAGTCTCTTCTGCTTTAACCTTTA AAAGAAGTAACCTGAAGTAACTTGTTGTTAACCAATCAGCTTTTTTTTTCTATTGTTCTG TTTCTTTGTTCCCTTATAAAAGGCACTGTTCTGACATTGCCCAGTGGAAGCTCAGTCTCT TTTATAGAATGGAGGCTGCCCACTTACCAAATAATGAATAAATGCCAATTAGATCTATAA CTAAATTTGTTGTAATTTTGTCTTTTGACAGGTGTAAGATATATTACAAGGTCATTTAGT AATACATCCATTGCTAAATGAATTAGAAAGCAAATTAAGTTAAAAGCAAGACAATGTTAA TTGCGCTTATGTTGATTTTTGTCAGAAGAGACCTAAGTACTTCCTGGTAAGCAGCTTTCA ATATAAACAAGAGCCCTGCACCTCTCTATCACTTCAAAAATAGAATACTGCAACGCTAGA AAGGCAACACCCAGGCTTTAGACGCACCTTCCAGAACAGACTTTTCTAAATAGCCAGTAA CAGCTCGAGAAAGGGAGAAGATCAGACCTGCCTTTCATGCCCCCCCGACCCCAGGAGCAG GAGGTGAATCTTGAATACCTTTTCCTACCCACAGGTAGAGAGCTGACCGGGGAGAGAGGC CAGCCATATCCTCAGCAGGAGGATGAAGAAGCCAGGCCAACCCTTGATAGTACCTGACAG AATCACATGGGCAGAAGCAAACTCGAATGGCAGCACCAAAGGAGGTGTGAAATGCTGTGA TGAAAACACCCTTCCTCCTAAACACTCATTCCCAACAACAAAAAACACCCACTACCATTT AATATCCAAAAGAGTAACTGGTGCATCTAGCTCCAAAGATCTCTCACATGAAAGATGTCA GGCAGCCGGGAGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGCAGGT AGATCACCTGAGGTCAGGAGTCCGAGACCAGCCGGGTCAACATGGTGAAACCCCATCTCT ACTAAAAATACAAAAATTAGCAGGGCATGGTGGTGCAAGCCTATAATCCCAGCTACTCGG GAGGCTGAGGCAAGAGAATCACTTGAATCTTGGGGGGCAGATGTTGTAGTAGCCGAGATT GCGCCACTTCACTCCAGCCTGGGCGAAAGTGTGAGACTCCGTCTCAAAAAAAAAAAAAAA AAATGCCAGGCACAAGCAGATCTCAGGTTTCCTTCGAATTGAGGAAACTGATAGGCCTGC CAAAGACAGCCTATGTGGCAAGTAAATGCTTGTGATTAAGAACCTGAATATCAACTTGAC GGGGTGTGTGCTGGGGAGGGGAGAAAGAGAGGGTACACAAAAACATTTGTGAATAAAATT AGTTTTTACCTTCATTAGAATTGTTTCTGATAGCATATTTGACCCTGAATTTATATGTAT ATTAAATAAAAGAAGACTCTTAGGCACTAACAAATGTGGGAGGAGAGTGCTGAGGTTACT AGGATTTTATTACAAAGAAATGTCTTACTTCTATGCTTTCACAGGTTTCTCCACTAAGGT TATGTATAACTTATGCAAAAAATGATAAAGAATTACTTCAAGTGCAGGAAAATACGAACT ACATTAAGTACAGCTGCTTTGACTGCAATGCTCCAGGAACTGAAGGAAGTTAATGGCACC ACAGGTGCTTCCAAGACACGGGGCCCGCACGGTGAGCTGTCCATTGGCTTCCCTTGGAAT AAGCAGAGTATATTGCCTTGGAAGGAAAAACTATTTCCTCAAAGGGAGCAATGATCCCTC AAGAAGGCTGGACAGGGGTAAGCAGAATGCTTCCCTTCCAGCACTTTCCACATCTCATCA TTGCCCTCTCCCCTCCTAGGTCCCAGGCACTTTTAAAATCAACAAAAGCAAGACTTTTTC TCTTTTCTTTTTTGGCTACACTGGCATCATAACATTCTACTAGAGGTTAAGTCAATAATT CAAAGTTAAAACCTCCAACATTTGAGACTTGGTATTATTAAATAAATCACCTCCATTTTG GCAAATTTACATCTGTAACCAATTCATTTAAGATAAGAGCTCTCTATATTATGGAGAGTC AGTAAAATATTGGTGATAAACTCTATGATCTTGGGGAGGTCCTTAATCTCCCTAAATTTT AAGCTCCCTCATCAGTAAAACAGGAAAAGGGAAAATACATCTGCCCAGGGCTGATGTGAG GGACAAACAGGGCATTTGCTGCCCATAGATGCTTGGCGGGAGCCAGGCCCTAGGAAACAC TCCTTCAATGTTAGTATCACTGTCAAATAAAATACCTTTCTTTCCACATAGAACTGGTTG AAAAGAACTAAGAATTTCAAACTCTTCAACAGCAGAAAGGCCCAAACCATCCCCATCCCT CCCTATGCGCCCTTTCACTCACCTTTTCCAACCTCTACAAAAAGGATGAGCAGAACCTGC CCCACTGTGAAGGACACAATCACATCTTCTTTTGTTCACTGCACAAAATAAGGTTATGAA GTAGGAGTGTTGGTGGGAAAATGAACACACCTTTAAAATTCTAAAAAATAATATTATCAT CAAAAGCTAAAGGGTGACTGCATGGGCAGGCAACTTGGTCAGGAGAAGGAAGAGAGACAG AGAAGCAACGGGCCCTGTTGTCCCCCATGGGGAGTATCAGGAGGGCTCCCAGGACTCCTG TGGAAGAGGCAGGCCCAGCCCGCAGCCTCCCCAAGCTCTAGACACAGGTGAGGCTCTCTG GAGTCGAACCCTCCCTGGTGGCCAATGTGCGCAAAGCCCAAGGTGGACGTGACAATACTA CAGAGGTCTATGTCCTGGGATGGCACCGGATTTGAATTGCAATTGACTCACTGCTTACTT CCCTCTCCCCTTAAGTGATAACAAAAAATCAAATGTCCTCTTCATCTTCTAAAAAGTTTT TAAATTATGACACCTTTGAATCAAGAAAAGGGAAAGCTGCTGTGGCTTCTATGTTTCTCC TCAGCCCAAAATTCATACAGAGAAACTCAAATAGCTAAACTAATGAAGTATGATTTTTAA ATTCTCAATTAATAATTCAAAATGTTTCTTCTATGCTTTGAATCATGACATACACACACA CACACACACACACACACACACACACACACACACACACAAAACACCTACATTAGCTTTGAA GTAGCAATGAAATTAACTAATAAATAAACAAAGTAGGAAATCCATTTCAGGGTTTTTTTT CTATTATTCCTGCAGAACAAAATGTTATATAATACATAAATCATACATAAATTATGTATA TGATGATCTGTGATGAGAGACCTTTGAGGCTACTATTATAATTGTTTTTTGGGGTTGTTT TGTTTGTTTGGTTGGTTGGTTGGCTTTTTGTGTTTTTGGTTTTTTGTTTTTTTTTTTTTT GAGACAAGGTTTCACTCAGTCACCCAGGCTGGAGTGCAGTGGCACAGTCTTGGCTCACTG ACACCTCCGCTTCCAGGGCTCAAGCGATCCTCCTGCCTCAGCCTCCCAAGTAGCTAGGAT TACAGGCATAAACAACTGCTCCAGGCCTGATGTTACTATTGTAATTGCTTTCATGCACCA TAACCATGCTTGTATAAAACAGCAAATTTAATCAATAAATGTTGTGTGTGTTCTGACTGC TCCACTGACTGGCCGTTCCTCCATCTCTCTCCCTTTCCTTGGGTCTCCCTATTCCAGTGA TTTGAGGTGGTGAGAGAATAAAGAGAACAGCAAGGAAAGAAATTTACGAAGAAGATTCAG CAAGTGCAACAATGCAGAGGTATGAGAGGGCAAAAAGGCATTTATGAATCCTCAAACCAG GTAGGGGGTGTCATGGGGTGTGAGTGCTGGATTTCTGCAAGGCTCAGGGTTGGAATAGTC AGACGTTGAGCAGTGGAGGGGGACTCGAGGCATCTGAGGAAAAGGAAAAGTAGAGAAAAT CTTTCAGATTGAATGGAGAAGTTACTGAGATAGAAAATACGGAAAGGGCCAGGCGCGGTG GCTCACGCCTGTAATCTCAGCACTTTGAGAGGCCGAGGCGGGCAGATCACTTGAGGTCGG GAGTTCAAGATCAGCCTGACCAACATGGAGAAACTCTGTCTCTACTAAAAATACAAAATT AGCCAGGCATGGTGGCGTGTGCCTGTAATCCCAGCGACTCGAGAGGCTGAGGCAGGAGAA TCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCATTGCACTCTAGC CTGGACAACAAGAGGAAAACTTCATCTCAAAAAAAAAAAAAGAAAGAAAAGAAAAGAAAA TATAGAAAGAAGAGCAGATGAAGGGATGGAGATGATGCATTTGTTTGGGGGGTACATCAT ATTTAAGGTCTGCTCCAGTTATCCAATACTGCATAACAAGCCACCCCAGAACTTAGTGGT TTTAAACAACAGCATTTATTATGGTCACACTACTGTAGTTTGGGCATGGCTTGGTCAGGA CAGCTATTCTCTGCTCCACTCAGCCTCAGTTGGGGGGACTTGAAGACTGAGGCTAGGGGC ATCTGAAGGTGCACCCGCTCACATGAGGGGCTACTGACACCAGGAAGACCTAGCAACTGA GGTTTCCTGGCACCTGTCTCTGTCTGCCTGGCCTCCAGCATGCAGACTCAGGGTGTCCAG GCTTCTTACATGTTCGCTCAGGGTTCTCAAGGCAGCAGTTCCAAGAGAGGCAGGTACAAG CTGTGTGGCTTTTTATGGCCTAGCCTTAGAAGTCACATGGTGTCACTTCCGTCTCATTCT ATTAGTTAGAAATGTGTCACAAAGGCCAGCCCATATTCAAGGAGAGGGGAATCAGAACAC CTTTTGGAGGGAGGAGTATCAACGAATGTGTGAACATGTTTTAAAACCATCACCAAGTCT TTGTGGGATGTTGATGTGGGTAGATTCAGGAGTGACATATGGATTTCTAAGAGAAAGAGC TGGGCAGGATATCAAGGTTTAGGAGACCTGAGGACGTGTGATATTTGAAGCTATTAAGCT GTTTAGATGGCCCAGGAAAAAGAATAGGAGAAACAAGGAGAAATGAGCATGGAATGTGAA CATCTCAGGGGGAAAGGAAGGTACGAATTAAGAAATGCAGTGCTGGACTTTCCAAGGCTG TGGGGATGCCAAGTAGGTTGAGAGGGAAGAGTAGATACTGGATTTGGTGATAAGAAGCAG TGGTGGATAATGCTGAGAGATTTGGGCTCTGTGGATTGGGGTAGAGTAGAAGAGAATTGG GGTCGGGTTGAAGAGGAGTGGGGTGGGGTGGAGAAGAATGGGAGGGCTGGTACAATGGAT TCCAGGCCTGCAGGAATGGGGGAATGGTAAAGGGAAGGCAACCAGAAAGGGAGACTGCTC TTTGCCAAAATGGAGCTGATTATTTAATAATACCAAGTCTAACCAGTGATTTGAGGTTCC CGCTCCACTTTGGATTGGAGGGAATTCACAAAATGCACTTTGAAAAGCTGGTTGCCTCAT CAGACTTCACTACTTTTCAAATTTAGTATCTATAGTCATCATCATGAAATTAATAATCCA GTCAAGAGAATGTCATCTGCAGTGACCACAGCCCCAGACAGAGCCCAACCAAGGCGAAGA CAGGGCTCCTGGAACCAGAGGCCCCTCTTGAAGGCTAAAAAAAAAAAAGGAAATAAGTTT GGGAAAGGATGGTAATGCTGGGAAAAATAAAACTCCTAAACCAAGAGAAATCTGCCATGC CCTCTTTACCATCAGTCAGGATTTTCATTGAATCCCTGACACAATCAGCAGTGTAAAGTC ACTATAAAGTCACAGCACTATAAAGTCACCAGGAGAGGCAGGCTTGGCCGATAGGTTTCC CCCTCAACAATGACCTGAAGAAAAGCACTGACCGACTCTCAGGTCGAGGAACTGCTGTTC TGGAATGAAAATCATTTCTCAAAAAAACCCGAGCGAGAATAGTTAACAAATCTAGAAGCT GCACAAATCAGTCCCATAGCCAAGGCACTCCACGATGAAAACAAGCTTCAGGTTGGCCCT TAGAAATCACTGGTTAAAATTCTAAAATCACAGCATTACTACAATTTCACCCAAATGTCA CCTCTAGACTAAACTGCTTCTCTGGCTATCATACCACCCAGGGAAAGTATAATACTTTCA TTCTGCAAATATTTAATATGTTCTTATTCTCTGCAAGGCTCTTACACATTAAAGTGAATT ATTGCTTACAGACTTGAGCTTCTTGAAGGTCAAACTCTACGATATCACTATTAAAATACA TTTTGCATTAAAAGCATCTTAACTAAAACCAGTGGCATCCACAGGCATAGCAAATCCAGT TATTCTCCCATGCCTCTAGTTTCTGCTCTCATTTTACAAACACACACAAATGCCAAACTA CTCATCCTCTCTACTGAGGAACTAAAAACGACATTCAAATTTAATATCTATAGTCTATTT GCTTGGGAATATTTGCTTGGGAATAGCCAAGCAAATTCCCATCACTTAATCCAAATTTCC CTTTAAAACACCCATGACTTCTCCAAAGAGCAGTTTCCCTTTCCGGTTGCCTTCCCTTTA CCATTCCCCCATTCCCACAGGCCTGCAATCCATTGTACCAGCCCTCCCATTCTCCTCCTC CCCACCCCACTCCTCTTCAACCCCAACCCAATTCTCCTCAACTCCACCCCCCACCCCCAT CCATGGAACCCAAATCTTTCAGCATTATCTACCACTGCCAGAGTGGTGGATAATGGGGGT GAGGGAGATGCAAACATTCAGTCAATAGCAGCTTTCAAGTCCAAGTTCAAAGGTCACCTA CTTTGGGAATTCTTTTCTGAAGACCCCAGCCAGCGTTGCTCACTTCCTCCTCAGCCAGGG TTATAAACTTTTCACAACATCTACTCTACTACAGCAGCCTATTTGTATGTTTGTTTCTTC AGAATGGCCTATGAGCCTGAGAGCAGGCTCAAAGCCTAGATCGCATCACTGCACTCCAGG CTGGGCAACAGAGCGAAACCCTGTCTCAAAAAAAAAAAGAAGTAGGCCGGGCGCGGTGGC TCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCTGATCACGAGGTCAGGAGG AGATCGAGACCATCCCGGCTAAAACGATGAAACCCCGTCTCTACTAAAAATACAAAAAAT TAGCCGGGCGTAGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGA ATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAG CCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTAA ATAACTAACTTCAATAGAACCGCATCGAAAATGTGTTTATGAAGTACTTATTGAGCACTA TGTCCAATATCACACTTGTCTCTAAAGAAATAAAATGTTTCGTTTAAACTGGGAACCACT GAGTTAGCATTTTACAGAAGTATCTAATATTCAGTTTCAAAAATCAGTATCTATTGAGCA CCAGTACTAGTAACAGATTTGTACCTAATTTTCATGCATATGTGAGATATCAGCCTTAGA GAAGTTTAGTGACTTATCCAATGTCTCACAACCAGAAAATGATGAAGCCAAATTTTGAAC CTCGATATGACTTCAGGTTCAGTATTCTGAACTAATTTACAATCAATTCTGATGCATAAG ATCAGACACACTGGCCAGACTCTGGTATAGATACACTGCTTGGTGCTCCTTTCCATGGCT CCTACCACAGCTGTACTGTGCTTTTGAACAACACCTTTGCAAGGAAAAGGAAGATTGTCT GCAACTTTTATGTAGTATAGGTATAGGCTGGGTAAGGACACGTACTCTCTAGCCAGACAT CACAGATCAAAATCCCAGACCTGTCTGCGCCAAGCTGTGTGCCCCTGAAAAAGTTATTAC TCTGTCCCTTCATGCCCTGTTTCATTTGTAACGTAGGGATACTGTTAGCATCTGCTCATA GGGTATGTTCTGAAATTTTTCAAAAATAAAACATGAAAAGCATTTAGACAGAACCTGACA TACAGAAAACAATAAATGTTGTTGCTGGTAACCACAGTAGTTGTATTACTAAAAATGACC CAGTAAAACCCCAGCTGGAAAACTTAATTGTAATGCAAAGCTGAAGCTCTGTTACTTCCG ATTCCAATTTTGTTTCAATTATTTGGAAAGAAAACATTTCTTTAAAAAGTATGAGATGTT CCTAGCCCTATAAACTGATTAGAAAATGTAGTTTAGGCCAGGCAGTGGCTCATACCTGTA ATCCCAGCACTTCGGTAGGCCGAGGGAGGAGGATCACTTGAGCCCAGGGGTTCGAGACCA GTCTGGGCAACATAGTAAGACCTTGCCTTTACAAACAATAAAAAAATTAGCCAGGCATGG TGGTGTGCGCCTGTGGCCCCAGCTACTCAGGAGGCTTAGGTAGGAAGATTGCTTGAGCCC ATAAGGTCAGGGCTGCAGTGAGCCATGATTGCACCACTGCACTCCAGCCTGGGTGACAGA GCAAGACCCCATCTCAAAAAAAAAAAGTAGTTTAAATTTTTCTTGGACTCCAGATTATTC TCTTAGAGACAACAGATTTGGAACGAAGCTTTTGTAGAGCTCTCCACATCCAGCAGAGTA CATCTGGGGAAGTCGTGATCATTCAGATTATGTTTCCTCATATATAAAATGAAAATGTAC CAGTCCTACCTTCCTGCAGCACTGAAAGACTGAAACAAGATAATATGTAGAAAATTAGTA AGAGTTCTCAAAGGCCATGTGGTATCATCGTCATCATTCTCATTCTGGGTTCTCATAAAA TAATATTCCATACTTAATATTCCAACTTCCATATGGAATATTCCAACTTCCATACTGAAA TGGAAGATTAATCATCCATTTGCCAAATGTCTCAGGCAGGCAAAATGTTTGCATTTTTCC CTCTTTACAGAATTTTTGTTCTGGTTTACTAGTAGCAAGCACTTTCCACTACTGTCAACA TACTGCTTGCCCTTCTGAAATGTGTTTTTTAAAAACTACTACTAACATGTGCTAAGGCCA TCCATGTCTCCTAGGCTCAGAATGCATTAGAAGTAAATAACTGGCTGGACACGGGCGGTG GCTCATGCCTGTAATTCTAGCACTTTGGGAGGCCAAGGAGGGTGGATTGCCTGAGCTCAG GAGTTCGAGACCAGCCTGGGAAACGAGGCAAAACACCATCTCTACTAAAAATACAAAAAA AAAAAAAAAAAAAAAAAATAGCCCGGCATGGTGGCACATGCCTGTAGTCCCAGCTACTTG GGAGGCTGAGGCACGAGAATTGCTTGAGCCTGGGAGGCAGAAGTTGCAGTGAGCCTCAAT CACTGCACTCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTCAAAAAAAAG AAAAAGAAAAAAAGAAGTAAATAACTAACTTCAATAGAACAGCACTGAAAATGTGTTTAT GAAGTATTTATTGAGCACTATATCCAATATCCTTTCAAGAATAAAAATTTAACCAACACC GTCTCTTCTACCTATGTATACACACACATTCTTACATACCTGCCTTAGGAGCAAAGTACC AATTTAACTTATATTCACAGACAGATTTTCAGTGATTATATGTAAGACTATAAGCATATT TAGAACATATATTCCTATCTCCCTGCCAAACCATGTTCCTTCTTTAATTCTTAGTCTTTT CTATCCAAATCCATCTGACTCTATTAATGCTAGAAGTCTTTTTGATTGATGTATGTGCAA TATGAGAAATATTTATGGAGTACCTACTACATTCATACTTGAACTGCAAGCTGGGAATAA AATGTAAGGCAGTCTCCTATTCTAGTGACACTATTTCTAGCCAAGTACACATTCTAGTGG GTTGGATAAACTATCATCTTTATTTCTTAAGCCCTCCTGATTGGACCATAAGCTCCTTTT CCACACCACAATGCCTCCAAATAAACTAAGGATACAATGGGTGAAATTTCATCCTGTTAA TAAGTTCCCAATCCAAAACTTTTATCAAGAACACATTTATATATATATATATATATATTT TTTTTTTTTTCTGAGACAGAGTCTCGCTCTGTCACCCAGACTGGAGTGCAGAGGCATGAT CTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCTG AGTAGCTGGGACTACAGACATGCACCACCACGCCGGGCTAATTTTATATTTTTTGTAGAG ACAGGGTTTCGCTATGTTGGCCAGGCTGGCCTCGAACTCCTGACCCCAAGTGATCCGCCC ACTTCAGCCTCCCAAAGTGCTGGGATTACAAGTGTGAGCCACCGCACCTGGCCTTAAATA ATTTTTAAAACTGACATTTACATTTGTATAGCTGTAACATAAAACACACTCACCATGATT ATGAGCCAAGGCATGTAAATTAATAGCCTGTCTGAAATCACTATTTTTAGTACCAATTAC AAGTGTCTAAACAGAAAAGACACCAAGAAGGAAGTACTGAAAGCCACAGAAAGCCATGCA AATTACCCCCAAAATGTCACCTGGAAAATATTTGCTCCTAATACTGTATTTTGCTAATAA AAATAACATTGAAAGATCCAACATAACCAAAATGATAAGCAAAATAGAAAAAGTAAATAC TTGCCAAGGAGGGAAGGTGACAGAGAACAATGAGAAGGCAAGACACACTAAGATCCCAAA GTAGATAAGTAACAATCTCTAGAGGGAAATACAAATGGATAATAACATCTATAACCTCTC TAGGAAACAGACAAATTGAAGCCTATAAGCTCTGTAATTTTTTTTTTAAGGAAATGACTA GAGAGACTGAGGCAGAAGGACTCCTTGAGCCCAGGAGTTCAAGGCTACAATGAGCTAGAA TTGCATCACTGCACTCTAGTCTGGACAAAAGAGAAAGACTCAATCTCTTAAAAAGAGAAA AGAAAAAAAAGACAATAAAAAGGCAATTTACGTAATAAGAAAAAATATTTGCAAACCAAA CATCCAATAAAGGGTTAATATCCAGAACATATATATAAAAAAGTCGTACAACTCAACAAC TAATCTGATCAAAAACAGGCAAAACAGCCTGGCACAATGGCTCAACCTGTAAGTCCAGCA CTTGGGAGTCTGAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGGTTATGGTAATCTA TGATTGAGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTGTGTCTCAAAACACAAC AAAACAAAACAAACAAACAAACAAAAAAAACGGGAAATAACGAGTGTTGATAAAGATGGA GAGAAACTGGAATCCTTGTGTACTGTTGGTGCAAATGTAAATTGGTAAAGCTATTATGGA AAACAGTATGAAGGTTCTGAAAAAATTAAAACAGAATTATCATATGATCCAGCAATCCCA TCTCTGAGTATATTTCTAAAAGAAGTGAACACAGGCTCTCAAAGAGATATTTGCACACTC ATGTTCATTACAGCATTATTCACAACAGCCAAGATGTGGAAGCAACCTTAATTTCCACTG ATAGATAAATAATAAAGAAAATGTAGTACATACATACAATGGAATATTATTCAGCCTTAA GAAGGAAATTGGGTCATGTGCTACACACGCATGAGCCCCGATATCATGCTAAATAAAATA AGCATCACAAGAAGACAAATACTGCATGATTCCACCTATATGAGGTATCTAAAGTGGTCA AACTCATAAAATCACGGTTTCTATGACTGTTACCAGGGGTAGGGGATGGAGGAATGGGGA AGTTGGGAAGCTGCTGTTCAATGAGTACAGAGTTTTCATTTTGAAAAATGAAAAAGTTTC AGAGATCTGTTGCACAAGGTACATACAGTTAACACTATCGTACTGTACATTTAAAAACGA TTAAGATGGTAAATTTTGTTATGTATTTTTTTACCATGAGAAAAAGAGGGCATTGACAGT TATGTTTTCCAGAATGAGATTCAGTAACAGGCATCGAAAAGCTTACATATATTCACCTCC TTTGACCTGTCTATGGAAATTTATCTTAAAACAATTTCTCTTAAAGCAGTATCATAGCTA AAATGGAATGTAAACCTACTCCAGGAGAGAAAGAGTTAAATAAACATTTGAATAGTGGAA GAGTGCAATTATCAAAAATTATAGCTTGGGGAAACTTTTTTTAATGATGTGGTAAAATTC TTATTATCAAATAATATCCAAAACAAAAAACAAAACTGTTATGTGTAGTGTATACAGTAT AACCCTAATGAACATATATTGGGGTATTGAATAAAGAAACAGACCAAATTCTAACTGTGA GAGAGAGACAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACAGACAGACAGAAAGGGGAA AGGGGGGAGGAGAGAGAAGGAGAAAAAGATCTGCCAGCATGATTTTTGTTGAATTTTCAC CTAGATAAGTTGATTCTAATGTTCGTTTGGAAATAGTCTGGCAAGAATACCTAGAAAAAA ACTGACAGAAAAAAAAATAGAGTAATCAGAGCAAACTAGCCCTTCCAGACATTTTTACAT TTTATGAAGCTACAATAACTTAAACTAGGTTTAGCTGCTGGCAATGAACATACAGATAAA GAGAAAAGAAAAGAATGTAAGAATTTAGTACATGACAACAGTGGTATTTCAAATCAATAG AGGAAGAAGCCATTAGTCAATGAATGGTGTTAGGCAGTTGGGTGGCCAATTGGAGGTGGA GGTGTTAAGATTTATACCTCACATCTCATTATCAAAACAAACTCCAGATTGAGGAAAGAT TTAAACATAAAAAATAAAACCATAAAAGCATAAACTCAAAGTGAGGGAGGCATTTCTAAA AATGATTCAAAAGCTAGAATCCATAAATGAAAAGAGCCATTAGTTAGGCTGGGTATGGTG GCCCACTCCTGTAATCCCAGCAGCTTGGGACGCCCAGGTGGGCAGATCACTTGAGGCCAC AAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCATCTCTACTAAAAAATACAAAAA ATTAGCCAGGCATGCTGGCACGCACCTGTAATCCCAGCTACTTGGGAGGCTGAACAAGAA CTGCTCGAGCCTGGGAGGCAGAGGTTGCAGTGAGCAGAGATCATGCCACTGCACTCCAGC ACTCCAGCACTCCAGCCTGGGTGGCAGAGGGAGACAATGTCTCAAAAAAAAAAAAAAAAA AAAAAAAAAAAAGAGCTATTAGTATTTCTTCTTGGTTAAAAAAAATCACTATAAAGTCAA AAAAGGTATGACAAACTAGAAAAAAAATTAACAACTCATCTCATAAACGGGGTACATTCT ATAAAATACAATAGAAAAATTGGCAAAAGATATGGCCAGATATTTCACAGAAAATGCCAT GTAGATTGTAAACATATCAAAAGAAGTAAACTACCTTTATATTAAATATATATAGTAAGA CTTATACTGAGAAACCATTTTTCCCCTATAAGACAAGCAACAATGGAAAAGTGTGGCAAC ATCCTGGCCACATGGCAAGGGAAAGCAAACGCTCGCACATGCTGGTGGAAGTATAACTGG CACCACTTCTATGGAGCAGAATTTGGCACTATCAAAATTGAACAGCCACATTCTTCTAAG AATTCTTCCTACAGACACACTGGCATTTTTATGGAATGACTTGCATACACATACATTTGC TGCAGCTTTGTTTTAACAGCAAAATATCAGGGTGAAGGAGTTCAGGACACAGCATCCCAA AACATTCCACTTTAGCATGCTGATTATTTTGGGCTAAAGGCACTTGAAAAACAGCAGGTG TTAAGAAGGGCACCCAAACCTCCTCTCTTTTTCCTGAAAGCAGAAGATGAAGCTCCCATA TGAAAGATGTCCTCCCTCTACCAGGAAGAAAGAAACATTCTTATCACAGGAAGTCCAAGC CCAAAGAAATCTGCATAAAGAAACCTTGCTAAACTAAACCTTACCTTCCTAGTTACTTTT CCACAACTGCCACTCTTTTTTTGACCTAGTATATAATCGATCAGGCCAAGCCACTTCCTT GAGTCTTCATTCCTCTTGTGAGGGTAAAAGGTATGTAATACATAAAAAGCACTAAATAAA ATTTGCATGCTTTTCTCCTGTTAATCTATCTCATGTTGGTTTAATTCCTAGGCCTCGCCA GAAACCCTAAAAGGGTAGGGAGAAATTTTTCCTCCCCTACAAGGCAAAATGTAAATGTTC ATCAACAGGGAACAAGTTAAATATTGTCTATAACAGTATATAAAATGTTACATCTATAAA TAAATACATACAAATGGCCATTAAAAATGGAGCTGCTCTAGGCCAGGCGCAGTGGCTCAC ACCTGTAATCTCAGCACTTTGGGAGGCTGAGGCGGGAGGATCACTTGAGGCCAGGAGTTC GAGACCAGCCTGGACTACATGATGAAACCCATCTCTACAAAAATAGAAAAATTATGGCGT GGAGGCACACGCCTGTAGTCACAGCTACTCAAGAGGCTGAGGCAGGAGAATCACTCGAAC CCAGGAGGTGGAGGTTGCAGTGAGCCAAATTGGTGCCATTGCACTCCAGCCTGGGCAAGA GAGAGAGACTCACTGCAACCTCCGCCTCCCAGGTTGAAGCGATTCTCCCGCCTCAGCTTC CCTAGTAGCTGGGATTACAGGCATATGCCACCACACCCGGCTAATTTTGTATTTTTAGTA GAGACAGGGTTTCTCCATGTTGGTCAGGCGGGTCTCCAACTCCCGACCTCAGGTGATCCG CCCGCCTTGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCACATGCGGCCATTA AAGTGTATTTTTTAAATACATTTAGGGTTTTTTTAAAAGGGCAAGTTATAAAATGCAATA TTCAATAAGAAATTTTGTGATTTGTTGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAG CACTTTGGGAGGCCAATGAGGGCAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGAC CAACATGATGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCTGGGTGTCGTGGCA TGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATTGCTTGAACCCAGGAG GCAGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCACCCTGGGTGGCAGAGCGAG ACACTGTTAAAAAAAATAATAATAAAATTGTGATTTGTTTAAAGCATAGATACATGAACA GGTATAAATTAATATGCTAACTATGATTTCTCATTCTCGCACAGGATTATGGGTAATTTT CTTTTTTCTCCATCAATATTTCTGATTTTTCTAAAATAGACAACTATTCTTAGGTTCCAA AAGGCATTTTTACATTCTTTTTTAAAACTTCCACTAAATATTAAAATTCCTTAATCCCCT GGAAACATTTTTCTAATAAAAATACATGGCTAAAATTATGGTTTCAGTACAGCTGGTACC CACTAGTTTAAATAAAATTTGGGAATGTCTCAGAAGAGAGATTTCACAACAGTCAATAAT TAAGGCAGAAATAATTAACCCCAAAAGGAAAATAATCTTAGCCTACAACAAAAGACTTAG TAGCACAGAAGTTCCAGGGATTTGGGTGTTCTTTTTGGTTTTGCACTGTGAGTGAGCGTA TTTGTTTTTATTACATGCATACATTATTCTGTTTTGAAATCTTGCTAAAAGATCACAACC CCTCCTACCACTCAGCTATTCCCCTAGGGACTAGGCAGCCTGCCACATAAAAATAAATGC AGGAAGTGAAGAAGAGCTAACAAAGACATCAGCACCATATGGAAATCACGAAACTGTTGA CCAAATAAATTAACAGCCTGGATGGGGTGGGTCACACCCAGAGACTTGGGAGTAGACCCT CAAAATTATTATCCATTATTCTCTACATTTGCTTTATTTTTAAATAAATGATACCCCACA TTTCTGTTATTTATTTCTAAGGCACAATTACAATGTTAAAATGATAGTGACATATTATTG TGTTATTCTTTTTTTGAAGCCTTTCCTCTCTAGTTTTTTGGCCTCAGGAACCATTCCTCT TCCCCTTAAAATTATAAAGTTGTTTTGCTTTGTTTAAATTCAAACTAGTATAATGTGTAG TGGGCTACGTGACTGTCACTTCTATATAACAGTGCTAAACTAAAGGTTATGACTAACATG AGAGCACTCAAGTATACATATTTATTCAGCTCCATAAAAGGTAGTCAGGAGGGTTTTCTA CACAATGTATGCTCTAGTTAGCAACACTGCTCTATCAAAGTAGGAAATACCACACACAGT AAATGTGCTGCGCTGAGCTTAATGCTTGGAAACTCTTGAAAGGCATGATGCAATTTAACG TATTTTAAATCATTTGATGTTCACTGAACTCTCACTGTAAGCAGAGTATTGTATTCAAGC CCTAGGTATGAGAGAAAGTAGAAAAACAACAGAATCTGGGCCTGATACTACAGAGCATTA GAATACTCGTGGTTGAAAACATAAGGAAAACTCAGTGTTTATTTTAAAAATTTACAGCTC TGTTAAGTACAATCAGTAGCAAGAACAGATTTTTTGATAACTTCACATAAGAAGGTTGGA AGAGGGATTTTCAATAGATAAATGCATGTAAGACAAGAGGTAGGGCATTTAATTTTACAA CTAGAGTTTCATTAGGGATTTTTTAAGGGACAAATATAAGAAAACTCCATGTACATTAAA AACTATTAAAAGTTCAACAAATCCTAAAATTTTCTGCTTTGGTTTTAAGTATGTTGCCAA AATCACAATTCAGGAGACAATCACAGAGTTTGATAAACCTTATTTCAGCCAACACAGTTT GCTAGTGAACACCAGGTTTAAAATCCCAGGTTGTGCCTTTTCCAGTTTAAGGCAGGAGTC TTGCTCCAGATTCACTTAAGACTGAGTCATCCACTCTACTAGTTCTAAGATCTTCCATGT AAAGTTATCCTCCAAGCCCAGCACTGCCTTATCAGCAACTCTCTGGCTAAGTTCTGCTTC TTGAGAATAGACAGGGAAAACAGAACAGGAGAAAGTGGGAAACAAGAGATGGATTTGGAG GGACACAGAGGTTACTATGGCTGGGGCCTGCTCTTGGACACTTTCCTCACTCATCTTAGG CAGTCAACACATATTTCTAAGCACCTACTGTGTGCACTGGTAACATAAAGATGAAAAGGC AGGTAGGCAGGTGGAAGCAAGAGTAAGGAATGGCCAGGTGGTTTTGTTTTGTGTTTGTTT GTTTTTTGAGATAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTTTGATCTAAG CTCACTGCAACCTCTGCCTCCCAGTTTCTAGTGATTCTCCTGCCTCAGCCTCCTGAATAG CTGGGACTACAGGCCGGTGCCACCGCGCCGAGCTAATTTTTGTATTTTTAGTAGAGACAG GGTTCCACCTTGTTGGACAGGGGTCAAACTCCTGGCCTCAAGTGATCTGCCTGCCTCAGC TTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCCAGCCTTGGCCACGTTGTTC TAACACAGCAAAGCTTTGGAGTAAATGAACTGACCCTCCCAAGGCAGTGCCTCTTCTTTC ATTCGGAGCAGAGTCCTCCACCTCACCCAAAGAACATATGGGAAAATTATAGACACGAAA AGACTCATCTTACAAGATAAAGATTTGAAAAAAATATGTCTTAGAATTAGACACTTAAAC TAGTCCTATAAAAACTACACAAGAAGTTGGAATACTGCAGTGCTACCAATGACTGTTGAT TCTTACCACCCAAGCTAGAACACAAACACTACTAAAACTAGTTACTCCACTCACGTAAGT AAAACACAGCCGTTTAATTTACTTTGACAAGTACCAAACATAGTTATTCTAAAAACATCA TTATGTCAAACGACAGTGTGTAACAGATTAGTATACAAATACACATGGGCACGTTTGTCG TCATGTCTCCCCCGTCCTGCGTCGCCCCCATTGAAAGCCAGACAGACATAATGCTGACTT ACATGGTGGCCCCTAAGCCGGCTAACAATATATACAAGACATGTGACAAGCTTTCTAACT CAAACATTTGCATGTCTACTATGTACAAGTCATCATGTTATCCCACTCAGGACAACCAAA GATGAAATGTTTCTAACCTCAAGAAGCTTAAAATTTAGATAATAATATGTATGTGTATAT ATACGTTATACAGGTAATGTATAATATATATATACACATAGGTAACACATATAAAGCATA TTGTATGTAATGTTTGTAAGCACTTGTGTTAAGTCTGAAATTAATCTGAAGGGGAGCGAG GAAAGAGCTGAAAGACTCCAAAGAGTCTATCTTACAAGTAAATGAAAGTAAAGTACAGGC CTGGCCCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCA CCTGAGGTCAGGACTTGGAGACCAGCCTGGTCAACATGGAGAAACCTCTGTCTCTACTAA AAATACAAAATTAGCCGGGCTGTGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGC TGAGGCAGGAGAATCACTTGAACCAGGGAGGCAGAGGTTGCAGTGAGCTGAGATCCCGCC ACTGCACTCCAGCCTGGGCTACAGGTGGAGACTCAAAAAAACAAACAAAAAAAACACCAG AGTCTGAAAAAAATAAAGTACAAGATAGTATATTTGGAATATGGTTTGATTTACATAAAA ATGCACACATGACGGCACATACTGGAGGAAAATAAGCAATACATGAAAACTTGTGTCAGG GCTCAAAACAGGAGTGATTCCTATCCTCACTTCCCAAGATTACCTACCTTGTTTTCTTTT TTCAGCATTTATGTATCTTTTTAAAAGCGTGCCACACACATCTGCGTACAGTCACAGGCT TATGATCAGCAGAGATCTCTAGGATGAAACTATTTAAATCTGAAAACCATGGCCTACTAT TGCTCTATTTGGGGGTAATTTCACTTGAGCTGTTTTCAGAAGCAAGTGCACCCAACGCTA TGGTAAATTAGACTGAAGGTTTTGTGTTGTGGGATTTCACCCTTCCTACGAAAAGCTCTC TTCCCTCAAACCCACAGACACCACTCCACAATCTGGGGGTTTCTAGTATGATAAATATCT GCCTCCCAAACCCCCCATGGGTCATACGCCACCAAAAATCCTAACCACCTGAACTTAGAA GAAGGCAGAAAGTCTTAATTTATGAGGGAGAGAGGGGTTTCCCACCTGGAGGGACGAGAG CGACTCACTGTCCTCTGTTCCTGGTTCCAGTCACTTACAGGAGCTGGCTGCGCCGTGCTC CCTTCACGCGGCTTTCCACCCAAAGCGCATCACGGCCGCCAGCCCCTGACGCTAGCCCCT TCGCCACCTCCCAGAACCTTCTCTCCCTCTCCCCCACACACGCACACTCACACTCACACA TGCAGTCCCATCTGCCCCCGCCAGAGCCGCTCCTTCCAGGGCCCCAGGATGCCAGATCCG GATCCGGGAGATGCAACTTGCGGCGCCGGCCCAGGAGGCTCGGCACCTGCTCGAGCCGCC GGGCCGCGCTCAGCCCCGCGCCGAGCCAAAGCCCGAGTCCAAGCCCGAGTCCAAGCCCGA GCCCAAGCCCGCTGGGTCCGCGCCCTCACCTTGCTCGCCGCGGTCCATGTCTCCAGCCCG CCGCCTCGTGTCCTCTGCAGCACCCCCGCCTGCAGCCCGTCCCGGCTCGGATCGCCCGCC GCGCCGCGCAGAGCTCCTCCTCGCCTCCGCCGGCGACTCCCGCGAAGTCCCCACCCCCAG AGGCGTCGGGCGCGGCGGCGCCGCCCGCCCTCGGCCTGGAGCGCTTTCCTGGGGCGTCAC CCAACCACCTGACCCGGTCGACCTGTGCGCTCCGCCACGTCGGCGCGGGCGGCGCAGCGC TAGGAGGGCCGGGCGCACCCCGACTCCCGCACCGGCTGGAAGTCGGCCGGGAGGAGGGAA GAGGACGGCGAGGAGATGGACTCGGCCATGGAGGCTGCGTGGAGCCTGCTTGGGAACCGG GATGGCGTTTGCCTTCCACCATCAAGTTATTTATAAAATCAAAAGTTTCCTCCGAGGCCT TGGAGATGCCCTTTCTCTGCATCTGCGAACACCTACTTTCCTATACTTACAGTAGGAAAC ACAGGAACGTTATTTAGAAATGCCAGTGGCTCTTTTCTCTCTGTATTTTATTACCTAAAT AATGCCCTATGATGTCTTCTCTAACTAGGTCATAAACCAGCATAGGTGAAAATTGCAAAG AATCTCTTGAAAAATTATATAGTCTTTTCCATAGAATGCGGATTTTTTAGGTGACTAGGA AGATTTTCATATAATAAAAATCTGTTTTGAGTGCGGGACTGAGGACAACACTAAAATGAA TTAAATCAAATGAAATTAATTAAATTAACCGAAGGTCAGAATTATCAGCAGAGATCTTTG GAAAATGCGTGTTGAGGCGTCATGTCCGTTGATCAAAGGACAGTTTGAGGTTCCCGTAAC AATCCAGTTCTTTTCATTAGTAGCGTTAACAATCTGTTTTCACAGGGTTTTGCAGTTACT CGTCTTCCATGAAGTCACTTTGATTGTATGGGTCATGGTCTTCAGGTGGTGTCTCAATTT CGTAAGCTATCTGAGGCTGCAAATGAAGTGGGGCTTCTTTTCTGTGTTGCTTGACGTTTA GGCCGAAGCATTGTGTAGCACTCCACAGACAACAAAGAAGCACTTATTCAGATGTTTTAA AATTACTTGTAGTTACCTGAAGTGACTGTATGCTATTAATATCTCTATACTGTCGTGCTG TATGTAAAGTGTAGCTCTCTCCAGCCTGCATCTTCCAGTGTCTTCTGGGGACGTTTACTG TTTGACTCAACCAGATGTGATCTCTTCTATTTGAGTCCTTCTACTCTGACTGCACTTGGC TCCTCTCCTGTGGCACTCACCCCAGCACTGGTGCCAGGATGCTACCAGTGTATGTTTCAC AGTCCTATTAGGTTACAAGCTCCAGGTGGTAAAGTCCTTAAAATGGCCTATTAAAAAAAT CAAAAAACAGGCCTGGCACGGTGGCTCACGCCTGTAATCCCAGCACTCCGGGAGGCCAAG GCGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCTT GTGTCTACTAAAAATACAAAAATTGTCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCAC TTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACA CGGTGAAACCCCATCTCTACTAAAAATACCAAAAATTAGCCAGGTGTGGTGGCGGGCGCC TGTAGTCCCAGCTACTCGGCAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCAGAG GTTGCAGTGAACTGAGATCACGCCACTGCACTCCAGCATGGGCAACAGAGTGAGACTCCA TCTCAAAAAAAAAAAAAAAAGTTCCAGGTGGGCAAAGATTATTTTGGTCATCTCTGCATC CTTTAATTCTACCATGCAATTAATAAATATTGTAATTTTAAACCAGGCATGGTGGTGTTT GCCTGTAAACCCAGCTACTCAGGAGGCTAAGGCAAGAGGATTGCTTGAGCCCAAAAAGGT GCAATATTTTTTAAAAAATTTTTAATGTAACATAAAGGTAAATTTTGGCATCAGCAGAAA ATTCTGTATGTGGTAAAGAATTTTTGACTAGCTGATGCTGAGATCTATTGTATAGAAATA AACATCTGGAGAGACAATCTCTCAATGTACTAATTTGTGGACAAATAAATAGCACTTGAA CGTGAGTGTCCGTTACAAATATTTATTGTTTGTATCTGTTTAACTTACTATATAGTGATG AACTTGTTATGTATGCTGAAAGGAAAAAAAGTCTTATCTTTTGAAGAGCTTATAGAGTAG TTCACATGCAGCAGAGATGGCAAATAGCCTACCTGATAAACAGCCTTCCTGTTTTCCTTC CTAAGATAACCTAAATATTGTTTGGAGTGGCAATGTGCCCAGCTGAAACACTGGGCACTT CAAACTGCCTTGCAGCTGGAGGTGGGTCTCTCTCATTAATGTCCAATGAGATGTGAGCAA ACTGTACTAATTGGAATCTCCAAGAAAGCATTTAAAAAGAAGACAGACTTGGCAGCATTA CTTGGCCCTTCACCCTTCCCATTCCTGCTTAGAGGGGCAATAGCCATTTTGCAAACACGA GGAAGAAATTCACAAGCCAAGGACGGCAGAAAGAACCCAAGAATCCATGGCATCAGAGAC CTGCTTCTTACTGGAAAAAAATAAATGCCTGACTTTGTAAGGCCACTGTAGTTGGCTTTC TGTTAGATGGAGCCAAATGCAATCCCAACTGATAGAATGCGCCATATAGAAAATGCACTC TGGCATGCACCCACGTAGGTGGATACATGCAATCCTGAGCCTTAGAGATAGATTAACTTA ATTTTCTCTTTGAGGTTAAATGAGCACTGTTCATACTATAAATATCCTAGTACATGATAT TTCCACAAAAGCCTGCTTTTCTCTTACATCTTCCTACTACATGTATTTCTACAAAAGCCT GCTTTTCTCTTGTGTCTTCGTACTACTTCATTTGTTTTCTTCTGACAGAATCTGTGCTTA CAATTTATGCTGTGTTACTTCTGAAATGAACAGGTCTTATGTTTTAGCACTCTGAGGAAT CTCTGGAGAATGGCTAGCACTTAAACAGAGCACCTGGGTGCATTGAGTTGAACCACATTT AAAAGGCTCAGTACAGGAAAGAAACACTAGATTTACTTTGTGGTGTTATTGTTGATGGGA ACGTGGATTTTTTTTAAGTTTCTTTTTTTAAGTTTCTTTTTTCAGAATACTCATTTGTTG GTGAAATTTTTACAAGAAATTGTAAACTTCCCCTGAAACAAATGCATTGAAGCAAATGAA GGTATTGAAAAGGATAGATAGAAACCGACTTATGTAAGTGGAAAAACTCTATACTCTGCC CTTGTTGTATGTATCTTCCTTGACCGATAGCCAGCAGAAATCACACAGAATGTGTGGCAA GTGGGATGCTTTCTGTAGTCTTACCCCTCATATTTGTGGGGCCTGGGGCGAGGATACAAA TGGAGCCCCTGGCTTTCTCTTCTGGCTCTGTCCTTTCACTTTGACTCTGTCCTGCACCAG GCTGGCCCACTCCCTTGTGCGTGGATGCCTTAGGACATATCCCATCTCTATCCACCCTTT CCCATCAGCCGAGCCTTGGCCATACCTCCATTCTAGGGTTGCACTCAAAAGGACTGTCCT GGGAGAAAAGCTGAAGGCCTTGACAACAGATGTTGGCCAGTTTAGGCAAGAGATTCTGTA GTTATAGGTATCAGATGCACCGTTGATAAAGAGGGGGTAGATATTTGATGCTAGGGACTG CTCATCAAGGAGAACAAAAGTGGGAAGTCTCTATGGGACCCAGGGCGCCCAGTGGAGGGG CTTCAGGTAGCCTGGGTCTAGGGTTGCTGCCAGATAAGATAAAAGGACACCCAGTTCAAT TTGAATTTCAGATAAATGACAAGTAATTTTTTAGTGTAAGTATATCCCTGGCCAGGAGTG GTGGCTCACCCCTGTAATCCCAGCACTTTAGGAGGCCAAGGTGGGTGGATCACTTGAGGT CAGGAGTTCGAGACCAGCCTGGCCAGCGTGATCAACCCCTGTCTCTACTAAAAATACAAA AAATTAGTTGGGTGTGGTGGCACATGCTTATAATCCCAGCTCCTCAGGAGGCTGAGGCAG GTGAATCACTTGAACTCGGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACCACCGTACT CCAGCCTGAGTGACAGAGCAAGACTTCATCTCAGAAAAAACCCAAAAAAGTATACCCTAC AATATTTGCAACATACTTATACTAAAATTTATTATTTATCTTAAATTCTTAGCAAGTTGT CTTATATTTCTATTTGCTAAATCTGACTACCCTACCTATGTCAAAGGGTAGTTCTGGCTC TCTGATTGTTCAAACAAATGAAGGCATATGATACCACAATTTTGAAAATTATATCATCAT CCAGGAGAAAGATAGACTCTTCCTGCTTGAATCATGGTAGTAAACAAAGGGATGAAGGTT AGGAGGCCCAAGAGATCAAGAACAAGTTTTGGAGAAAAATTGATTTAATGTCAGGTAATG AACATTTTTTTGCTTAAGATAATTGAATAGCCATCTTATTGTATTCTCTTAGCCATCCAT GTAAGAGACTGACTGTGAATATGAAATAAACAACTTTTAAAAATGTGTAGAAACAGGTAT TGGCAGGAAAGAGTACTTAACACTAATGGAGGTTGGACACATAAATACCTAAACATTAAC AGGAAACGATCTCACACTATTGATTTTGGCTACATTAAGAAAAGCCATAGACACTTAATC TTTCTTGTATGTTTTTAAGCCACTCTGGATTCTGTGTATTTATCAAATTACATATGGGAA CTGGGTAGGGAAGGGAGTGCTGGGAGAGCCATTGTCCCTTTTCTCCTGGAGTCTCCACCA TCACCGTTCTAATCTTTTCATCTCTCTCTAAGATTACTCCAGGGTATAAAATGCATTAGA GATATGTATATTTAACAATTAAATGATTAACAATATTTCTAAATTTTTACACGGTGTTCA ACTCAGTGTCTTACAAACCATTTCACCCCTGCAAAGATAGCTAGTTTTCCAGAATGCCAA TGGTCCTCTGGCAGAAATGGTGTAGGCCAGAATGGCAAGTGCCCAGGGTCTTTGATGAAG AGCCAAATTCTGTGCCACTGTCACCAAAATATAACTCTGCAAGACCAGAAACAACTGAAA ACTCTGGAGTGGATTTATCTAAACCATCACTTTAAACTATCTGGCCAGGCACAGTGTCTC ATATCTATAATGCCAGCACTTTGGGAGGCCAAGGAGGGAGGATCATTGGGGGTCAGGAGT TCAAGACTAGGCTGGCCAACATGGCGACTAAGATACAAAAATTAGCCAGGAGTGGTGGTG GCACATGCCTGTAATCCTAGCTACTTGGGAGGCTGAGGCACAAGAACAGCTTGAACTCGG GAGGCAGAGGTTGCAGTGAGCAGAAATGGCACCACTGCACTCCAGCCTGGGTGATGGAGT GAGACTCTGTCTCAAAAACAAAAACAAACAAAAACATCACTATGGATCTGAGTGTGGTGG CTCAGACCTGTTATCCCAGCACTTTGGAAGGTTGAGGTGGGAGGATTGCTTGAGTCCAGG AGTTTGAGACCAGCCTGAGCAACTTAGTAAGACCTCCTTGTCTCTACCAAAAAGTCAAAA GTTAGCCAAGCATGGTGGTATGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGAA GAATTGCTTGAGCCCGAGAGGTTGAAGTTACAGTGAGTCAAGATTGCACCACTGCACTCA GTGTGGGCAACAGAGCAACACTCTGCCTCAAAAAAAAAAAAAAGAAAAGAAAAAAGAAAA GAAAAGAAGAAGAAAGAAAAGAAAACATCACTATCTTAGGCCTCTCACTTAAGCTTCTCT GGTTCACTGTCCTCATCTCTAAACTATGGAGTCATACTTTAGGATAAAGATGGCATATCA GACACATTTTTATTGATTGATTGATTGAGACATGGTCTCAGCTGTTGCCCAGGCTGAAAT ACAGTGGCAGGATCAATGCAGCTCACTGCACTGATGTGCAGCTCACTGCAGCCCCAACCT CCTGGGCTCATGCAGTCCTCCCATTTCAGCCTACTGAGTAGCTGAGACTACAGCCATGAA CCACAGCATCCAGCCTTATTTATTTTTAAAATGTTTTTTATTGAGATATAACTCATGTAC CATAAAGCTCACCCTTCTGAAGTAAAAAATTAAGAGGTTCTTGTAAATTCTCAACATAGA TTCATTCTTACTTCCTCTCTATGCTGCTAAAATTACAGTAAAGAGATAAACTCACAAGGA CAAAGAGAATGTGAGTGTCTACGTAATGATAATTGATCTTGTGAATCTGAGAAGGCCAAA TGCTAAACTGGGAAAGCCAAGAAGAACCTAATTTCCACTGCAGCACTTCCAAAAACCTCA GGACTTGGCATCAGGTATCTGTGGATGTAGAAAGAAAGTGAGGCTCAAAACAAGAGGATT GGTTGAAAGTTTACTTAAGAAGTTGGGTCCCATCCCCTTCCCTATTCTGCAAGAATACTA AAGTGGCTTCTCTGGAGAAGGAAATTTGACAATCTCTTTACTAGAAGACTAAGTACATTT GAGGCTGAGGATTTCCTAATACAGGCAGAAAAATTCATTAGCAGTTCACATCATGAATGC TGTTTCTCCAGCCTTGCTCTGCTTGGTTCTCAGGATGCAAACAGCCAGGCATATACTGTG AAAGCAGGAGACTGAAAGATCCATCTCTCAGGAATTTAACCAACCTAAGAGTAAAGAACC AAAAATGTTGACATTGGATAAACCAGATCACCTTACCCTCAAATCTATGGTCACAAATCT TGCCCACGTACCTAAAGAGACCAGTCAGCTGCTTCATGCTCAGGGCAGGCAGCCATGATC CAGAGAAAAACCCTGATATGGTTTGACTCTGACCCCACCCAAATCTCATCTTGAATTGTA ATAATCCCTATGTGTCAAAGGCGGAGCCAGGTGGAGATAATTGAATCATGGGAGCAGTTT TCCCCATATTTTTCTCGTGGAAGTGAATAAGTCTCACAAAATGTGATGGTTTTATAAATG GGAGTTACCCTGCACATGTTCTCTCTCTTGCCTGCTGCCATGCAAGACATGACTTTGCTC CTCTTTTGCCTTCCACCATGATCGTGAGGCCTCCCTAGCCATGTGAAACTGCGTGTCAAT TAAACCTCTTTTCTTTATAAATTACCCACTCTCCAGTATGGTTTTATTAGCAGCGTGGGA CCCAACTAATACAAGTCCCTTAATGGAAGATAAAGACCAAAATAAACACCATAAAAAGGC AACTTACAGGAAACAAACTATACAAGGAGAAGGAAACAAACAGATCTTTAAAGCTATTGT TATTATATTCAGAGAGATAAGTGAAAATATCCTAAACATGAGACAAAAATAGTTTGCTCT ATAAAAAAATGGAGCATTCAGAGAAAAACCAGTTGTTAGAAATTATATTATAGCAGACAT TAAAACTCCTGTGGTAGGTATCATTTGGGATAAAGATCTCCAAGGATGTCTGTGTCCTAA TCCCAGAACCTTTGGCAAAAAGGGACTTTACAGACTTGATAAAGGTTAGAGATCTTGAGA GAGGAAGATTATCCTGGATTATCAGATGGACCCACTCTAATAACATGTGCTCTTTTGTTT TTGTTTTTTGAGACAGGGTCCCACTCTGTCACCAAGGCTGGAATGTAGTGGCATGATCTT GGCTAACTGCAGCCTCGACTTCCAGGATTCAAAAAAATCCTCCCACCTCAGCCTCCCAGG TAGCTGGGACTACAGATGAGCACCACCACACCCAGCTAATTTTCATATGTTTTTGTAGAG ACGGGGTTTTGTCACGTTGCCCAGACTGATCTTAAACTCCTGAGCTTAAGTGATCTGCTC ACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGTGCCCCTGCACCCCACCTACATGT GCTCTTAAGAGCTGAGAATCTTGTGACTGAGAGATGCCACAACAGAAAAAGAGGCAGGAG AGTTTCGAAAGCATGAGAGGACTTGACCCACTCTTGCTGGCTTTGAAGATGGAGAAAAGG GGACCATGGGCCAAGGAGTACGGGTGACCTCTATAAGCTGAATGAGCCCTTAGTTGACCA CCATCAAGAAAACAGGACCTTAGCATACAATCATGCGACACCGAATTGCAACAACCTGAA TATGCAAGAAACAAATTTTTCTCAAGAGCCTCTAGAAAGAACATACCTTGTTAGTCCTAG ATACCTTGACATTAGTCCTGTGAGGCTCATGTTAGACTCCTGATCCTCAGAACCATAAGT TAATACCTCTGTGCTACTTTAAGCCACTCCATGGTTGGTTTGGAGTATAAAGTAAATTTT CTAGAGAGAAGACCAAAAAACAAAGGTATGAAAAATAAAGGGGAACATATAAGAAAATCA GAAGACTGATCCCAGAGGTCTAACATCCAAAAAAGAGGCCAAGAGAAAGACATGGAAGAA ACAGAAAAAAAGAAGGAATCAGTGAAATAATTCAGGGAATTTCCCCAGACTGAAGGATTT CCAGATTGAAAGGGCTCACTGAGAACACGGCACAAATTTATAAAGTTCAGAACACTGGAG ATAAAGACCCCACAAGTTCTAGAGATGGAAAAAAAATGGTCACATTCAAAGTAAAAGGAA TAACAATGGGTTTGGAGTCATGGACAACAAAACTAGAAGACAATGGAGGATTAGGCTTAA TTTACTGAAGAAAAGTGATTTCTACCTTATTTTCTTCTTAGATTGAAAAGACAGAATGGG AGCAGGTAAGAAAGTTAGGAATGAGTAATACTGAGGGGTGAATAGAAAGGATGAATCCTC ATCATTCATAGTGGAAAACTGGTGGATAATGCCGAAAACTGGAATTATCAATATATGCAA GTTATTTAAAAAAAAAAAAAAAAAAAACTAGGCCAGGTGTGGTGGCTCATGCCTGTAATC CCAGCACTTTGGGAGGCCAAGGAGGACAGATCACTTGAGGTCAGGAATTCAAGACCAGCC TGAACAACATAATGAAATCCAATCTCTATTAAAAATACAAAAATTAGCCAGGTGTGGTGG TGGGAGCCTGTAATCCCATCTACTCTGGAGGCTGAGGCAGGAGAATGGCTTGAACCAGGG AGGCAGAGGTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCC TAGACTCTTTCAAAAACAAACAAACAGAAAACCTAAATGATTTTGATTTGAAAGTGGTTG CCTTCAAGGAGGAAAATGCAAAGGGTAAGAGGGTGGACTGCTGGGTTTTTCTGTTTTGTT TTTTGCTTTTTTGCAAAAATCCTTGTTTGCCTCTTTAAAATATGTACATGTTTAACTATA AAAAACTAAAAACTGGAAAGTAAAAATAAAAAGACTGATAAATTAGTGAGACAATAAGCT AAAAAAACAAATTAGGTTGCATGAATATACTAGGTAGCACAAACTTTTTTTTAGGGAGAA GTTATTTGCTATTTCCCTGAATCCTTGAAGTAGCCATGAAATCTCTGTGTTTGTTCTTTG AAGAGAGCTCTCAAGCCCCACACATTTCCAGTGAAATATAAGGACCCTTACTGACACTAT TTCCAATTTTCCTTTCAGCTCTGAAAATCTATGGTGCGTAGGAAGATGGACAAAACATTC TTCGTGATGAGAAAGCAAAGCAGATTGTGATCACATTTTTGGAAAAAATAGATTTGCATA TTCGATCTTATGCACAGAAAGATATCTGGCAAGACATTGACAAATGTTAATAATAGTTAC TTCTTGATGATAGGCCCAGATTATTTTTATTATCCTCTTTAGTTTGTTCTTGATATTTTT TTAACACTGAGCTTATCATATTAACAGTAATCTACATTGTTTAATAGGTACGGGCTGAGC ATGGTGGCTCATGCCCATAATCCCAACACTTTGGGAGGCCGAGGCGAGTAGATTGCTTGA ACCCAGGAGTCCGAGACCAATCTGGGCAACATGGTGAAACCCTATGTCTACAAAAAATAC AAAAAGTAGTTGGGTGTGGTGGCGCATGCCTGCAGTCCCAGGTACTTGTGGGGTTGAGGC GAGAGGATTGCTTGAGCCCCGGGAGGTCAAGGCTGCCGTGAACCATGATTGCCCCACTGC ACTCCAGCCTGGGCAACAGAGTATAAGAACCTGTCTCAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAACACACACACAAAAAAGAAAGAAAGAAAAGAAACAGGTACAGAGTTT CAGTTGGGATGATGAAAAAGTTCTGGAGTTCTGTGAATGTACTGAATGCCACTGGGCTAT ACACTTTAAATGATTACAGTGGTAAATTTTATCTTGTGTATATGTTACAAACACAACGAA AAAGAGTTATCCAATACTTGCCCTTTATTCGCTTCCAATTAATTATTATAAATAACAGTT AACTGTTTGAGAGGGTCAGAAAAAATGTCAAACAAGTTTAAAGAAGATGTGACCAGCCTG GGTAACATAGACCCCATCTCTATATTTTAAAAATAATTTGTATAATTTTTTTTAAGTTTG AAGAAGACACTGAATACTGTGAAATTGCCTAACAATTGATATTTTCTGAAGGCAGCTCTC TTGGTGGGATGTAACTCCTAACTTTCTCTCAAAAGTTTTTGTTGTTGTTGTTGCTGTTGT TGTTCCATAAGGAAAATGAATTTAAGAGAAGTTTGGGCCAGGCACAGTGGTGCACACCTG TGATGCCAGCTGCTTGGGAGGCTGAGGAGGGTGGATCACTTGAGCCCAGGAGATTGAGGC TGCAGTGAACCCTGATTGTACCACTGCACTCCAGCCTGGGTGACAGATGGAGACCTTGTC TTAAAAAATTAAAATAAAAATAAAAACGAGGGGCAGTTTGATTCTCAGTAGGGGCATGAG AAAGATAGAGTAATATGGTTCCCCCAGGCAAAAAAAAAATTTTTTTTAATTTTGAGATAG AGTCAAAATTTAAAAAAAGATCACGCCAGGCTGGAGTGCAGTCACCTCAAGTGATCTGTC TGCCTCAGCCTCCCAAAGTGCTAGGTTTACAGGCATGAGCCACCACGCCTGGCCAAAATG TTTTGTCCATTGTTGTAGTCAGGGTCCCTGTCACATAGCTTGTGAGATGGAGATTTGAGT GCCGGGGGTGGATTGGTGAGCACCCTGGGATCCGACCTGTTGGGAAGAGAAGCCAGAAGG ATTCAATGGAGGAAGAATGGACTGTGTGTGATGCAGTCACAACAGAGGCCTCATCCCATT CCTCCAGAAGCTCTGGAGCCACAGTGTCTCTTCAGAGTTGTCCCAAATTGAAGCAAATGG CCCTGCCTTTATAGCCCCATGCTGATCCACCCTAGGAAGTGGGCTGCCCTCAGGAAATGA TCTTGGGCAAGGTGGCTTTTCAAGATTGATGGCAGTTCTCACCAAGGAACTTCCCAGAGG ATCATCAGCTGCCAACGTTCCCAGTCCTGAAGAGAAGATGTGGATGGCACCAGTGAGGGT CCTCGCCAATCATATATTCTAGAACATTCCTGGGCTTTTCGACCTGTATCATAAATCATC CATACGAATCAGAATAGAACTAAGGAGTGTCAACCAGGAAGTTAAAGACTAAACCTACCT TCCAGTGAAATTGGAGTTTAACAATAAGGAGAAAAAGGTTCCAGTCCCCACGTGTTAGGA CATTGACCCCAGAGCCTCCTCAGAGAGCCAAAAATGTACTCCAAATGACCCTGTAATGAT ATACTATGGTACTGTCACCAATGTCTTTTCAAAGTAGCTCCAAAGGAAGCTTTGCTCATG GTGTAGCTTAAGCCCAGCTCTTTTTCTCCAGCCCTAAAAAAGGAAAATAAAAATACTGAA GTCCTTTCATGGGCTTATTCCTAAAGCCCAAGATGCACAATAGTATAAGTGCTTTTTCTT TATGAAAACATTAAAACAAAAATGATGCATCATTAAAGAGACTCCCTCAATTATGTTCTG TCTTGCTTCCCCTCGAGGGAAACCGCCAAAGAAGGAGGAGGTTTATAAAGTAAATGACTA GATGCAGATGTGAAATGACCTACCAGAGAGCTACTTCTGCTGATATGGGAAAGAAATACT CTCCCTCCAGTCTCTACCAATAAACCAGCGGAGGTCTCCCCATTAGTCAGGGGACTTAGG AAATCCCACTTGCTGGCCTATGGATGAACTGCCTGAAAAATATTTCCTCAGGTTCTCTAC ATTTTCTTTAAGGTTTTGAATTCTGCACTGGAAAAAAGTTGAATTATTTTCTCCAATTCA CACTTCATTATATTCAATATTGCAATTTTAATGAAGCCAAAGATCTAAGTGAGGATACCT GCTCACATTCTGACTCTCTTCACAACCTTGGGGCGACAGAATGACATCTTGCAAATGAGG ACACTGCGACACAAAGAATATAAGGAAACCTACTGAAAATCAAATACCTCTTAAATGTCA GAACTGTAACTCACCAGAGATCTCCCTTCAAGTTTAGAGCTCTTCTCACTACACCACAAA ATGGCTCTGAGGGTGAATTAATGCATTGTCACAGCTTAAGTCAGGAGAAAGAAACAACCA CATCTGAACACTTCCTATTTAACCCAGCAGCCTGGTCCCATCCCAAAGGACAGACCTAGA ATCAAAAAATTATGGAATAGTCATGTGAATTGGGGCTAGAAACTTCTGTAAGTGAACATC TGGTTTGGTCCTTTGCCTTCAAGGAAATAACTTTATTGTTATGTCCATTTTCTTGGAATA GGAGTTGAGTCCAAAGAGGATCAGTAAGTGCCCAGGGCTTATGGTTATTGATGAAGAGAC AACCAAAGTTGAATCCTCAAAATTACTTTGTGGTATAGGAAACAGCCAGACTATTTTGAA CTGACTTTGGGGTATAGGAAACAGCCAGACTATTTTGAACTGACTTTGGCCATGTTTCAG GCAGCCCGGGAAGGGACATTTGCTCAGTAGGTGGAGTGGACTTCTGTGTAGACAATGAGG TTTTAAATTTTAATTTAATTTATTTATTTTGAGAGAGGGATCCACTCTGTCACCCAGGCT GGAGTGCAGTGGCGTGATCATAGCTCACTGTAGCCTTGAACTCCCAGATTTGAGTGATCC TCCTGCCTCCACCTCCCAAGTAGCTAGAACTACAGGCATGTGCCACCATATCTGGCTAAT TTTTTAATTTTCTGTAGAGACAAGGCCCTGCTATGTCACCTAGGCCTTGAACTCCTGACC TCCCTCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACAACGCCTGGCCCAG TGGAGTTTAAGGGGCGTCAGATTACTATTAAGAAACTGAGGCTGTGCACAGTGGCTCACG CCTGTAATCCTAGCACTTTGGGAGGCCGAGGTGGGTGGATCACTTGAAGTGAGGAGTTCG AGACTAGCCTGGCCAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGG GCATGGTGGTGGATGCCTGTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTT GAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATGGCACCACTGCACTCTAGCCTGGGC GACAGAGCAAGATTCTGTCTCAAAAAAAGAAAAAGGAAAAGAAACTGAATATACAAATGG ACATTGGTGGCTGGGTGCGATGGCTTACACCTATAATTCCAGCATTTTGGGAGGCTGAAG CAGGAATTCCAGACAATGGCCAGACTGTATATGACCATAGAACCCTGTCCCACAACCTGT GTCAACCAGATCAGAAAGCCAAACCATAGCCTATGCAGCAATCAACCCAGAATAGTTAGG ACTTTGCCCATAACTGTCAGGTTTCCTATTTTTTGCCTATTTCCAACTCAGGACCAACCA GAGGAAGCCAAATATGCTCCTCAAACTAATCATAGGAGATGCTCACTGCTAATTGGCCTG CTCCCGGCTTCCTCATGCCAAGAACCCCTAATCAAATCATACTGGAAGCCTTTGGTGGTT TTTTTGTTTTGTTTTTTCATTATAAATCTTCCCCTTCTCCTGGCTGCCTTTGAGTCTCTG CCAAACACAAATGATGGTGGCTGACAACCTGGATAGAGCAGGCTCTGAATAAACAGCCTC TGATTGTTCTCATTTGGGCATCTTTGTTTATTTCTACATTTTTCCTGGAGGTTCACAAGA CACAGGCTGCACTTCCCGCTGCTGCAGACGCCAGCCTTCAGTCAGGTGTGGCTTCAGGAA GGCCCCTTGTGTCTTGCTGCTTGTGGCCTCTGAGTCCATGATGACATGGTAAATCAGCAC CAGGCTTACATTCTGCTCTTTTACATTGAGTTCTTTGGCCATTTATTCTGTTTGGTACCC AGGTAATTTACTCATCCCCATTTGTTTGGCATCCTTCATGGAATCAGTTCCATTTCTTTT TTTTTTTTTTTTTTTCTTTTTTTTCGAGATGGAGTCTTGCTCTATCACCCAGGCTGGAGT GCAGTGGCATGATCTCAGCTCACTGCAATCTCCGCCTCCTGTGTTCAAGCGATTCTCCTG CCTCAGCCTCCTGAGTTGCTGGGATTACAGGCGTGCACCACCATGACTGGCTAATTTTTG TATTTTTAGTAGAGACGGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACT TCGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCAC CTGGCCCCCAATCAGTTCCATTTATTTTCATCCTTTTTGCTCTTGTTTGTGCTTTCTATT TGTATTATGCTGTCTAAAAGGATTATTTGACATAAAAGGAGAATCAAAAGGTATAGCCCA GACATAGGTCCTATTAGCCAATTTTTTTTAATCATCCTCACAGACTGGGGCATTTGTGGT TCTCACCAAAATGGTAGCTATTCAGACAAATTTTGTTGTGGATTACCAATAAAACTGAAT AAGTCACTTCTGTCTTTGTCATGATTTTTTCTCCCAGGAGCTTGGCTTTGATCCAGACAG AATGCTGTTTTTCTCTCTGCTTTTCTGCATACTAGGGGGCACAGATTGTGGGGTCTGCAT TCAGAGGTGGCCCACTGTCAGGTTGGGGCCTGAGACACAAAGTGCAAAACCATTACTTTT AAGTAATTGTTGCCCCCTCTCCAGGGGTTGTGTAAGTCTAGGTCTTCTCCTCTTCCAGGA AAAACTTCTTACTGGAACTCTCATTATAACCCTAATTCTTATGACTTCTTTCTAAATGCA TGACTTCACCAAGGTCCTTCAATGGCCACTCTGGGGAAACATTTGACTTCAGCAGTATTG TTCATTTGAGAGGAACCTTAGAAAAGAAGAGAAATAAACTTTCTCATGTCCAATGGGCAG TAATTTTTTATTGGTATGTGGAGGCCTCTGAATGAAATTTGGATTCAATAATTGGTTCAC TGAAAAACTAAATGGCCAAAGCTAATGAGGAATTTGACAAACTTAAGCAATAACAATCTA GACTCATTTCCCTAGTATGCCTCCCCACTGCTTGTTCTCAGCTGCTTCCCTACATCCAGC CCTCCCTCTTCTGCCTTATCCTTCTGATCTCTTTCCTTCTGCCCCTCCATAGACTCCTCC CTCCGCTTCCCCCACATCCAGACTCCCCAACCTTTCCTAACAACTTTCCTAAGACCTGAA AATATCAGTTGACTCTAAACATCAATCCTGCCCTTGAACCAGCATGCAACTGTAAAATTT AAACCTTAGACCCTCTGAACTTTATGACCGTTCTCAGTACAACCATGTGAAACATCAACC CCAATGATACATCATCAGTGGAAACCATAACAACACTACATTGAACTGGCCCAAGGGTCT CACCCAGAAGATCACATTAGCTGCTTCTCCCCACCTTGAACCATGGCCAAATCCTATTAG CTTCATCTAGATCCACTTATGCCTGAATGATAGTTCACTTCTGTTCTTCCCAGTTACGTG AACCGGTAATTCCCTTTTTTACTTAAGCTACCTTGAGTTAAGTGTCTATCACTTGTAATC AAAAGACTACTGATGGCTGAGCATGGTGGCTCACACCTGTAATACCAACAGTTTGGGAGA CTGAGGTGGGAGGATCACTTGAGCCCAGGAATTTGAGACCAGCCCGGGAAACATAGGGAG ACCCCACCCCTACAAAAAATTAAAAAATTAGTGCGGTGGTACGTGCCTGTGATCCCTACT TGGGAGGCTGGTGTGGAAGGATCACTTGAGCCCAGGAGGTTGAGGCTGTAGTGAGCTGTG ATTGTGCCACTGAACTCCAGCTTGAGTAACAGAGCAAGACCGTCTCAAAAAAAAAGAAAA AAAAATGCCGATGAATATAGTAGAAACTTACAAGATGTGCTAAGAAGTATGATTTAAACC TTGAAAGTCATGTGTAGTCACAGGTGAAGGGTTTTAATCACATGAGTGATATGGTCAGTC TATTTGACTTTCTCTGATTGGTCGTGAATTAGAAGTGAGGACAAAAAAACAGAAGCTGGC AGTCATTGACCCAGTCCTGACAGTTCTGTGCTGATTGCTGCAGAGGTTGTGATTTGGCTT CCTGAACAGGTTGTGGGCCAGAGTTCTTCATCATAGATGTCTAATCATTATCTATTTCTT TTTTTAATTTTTTAGACAGAGTCTCACTCTGTTGCCCAGCCTGGAGTGCAGCGGTGCATT CTTAGCTCACTGCAACCTCCACCTCCCTGGTTCAAGTGATTCTCATGCCTCAGCCTCCTG AGTAGCTGGATTACAGACACGCTCCACCATGCCTGGCTAATTTTTTATATTTGTAGTAGA GACGGGGTTTCACCATGTTGCCAGGCTGGTCTCAAACTCCTGGCCTTAAGTGATGCACCC ACCTTGGCCTCCCAAACTGTTGGGATTACAGGCATGAGCCACTGTGCCCAGCCGGATCAC TATCTATTTCTATATTCAGTCTCTCAGTCCCATTTTGGTCTCTCACTTTTGAGAAGTTCC CCAGCTCACAAAATGTTGGAAATCCAGGTTTTTACTTCTTGGAGATTGTCCAGTTGTCTC CATAGCTAATTGAGAGATCTTGACTTGTTGTATCATCATTGTGATCGTCCAGCAAGAAAA TGACCGAATGGATACATTTAAGACTCTGACGAGAATACAGTAGATCAGCATGATGACCAC TATGACAAAAACAAGAGCAATTAACATTACCTGTAAAATGCTTCAAAACCAGGAATCCCA ATTGCTCAACTCAGAACAAGAGAACACGATTGTGGGTGGTAGGAGGAGTATAGTTTTTGA GTAAGAGGTAATGCCTTACGAGGTTCTTATACAATGCTTCCTGTAAAGCATTTCTCAGTC ACTTGATGTAAAATTTGGTTTACCTCAGGTTAAACTCAAGTGGGCTTTTATTTTCCTTAG CAACAATAAGGGCTGTAACTCTTTAGAATAGAAATGCTTCAACCCATCCTGAAAATAGAT TCAAAATACCTAAAATATATTCAAATTCCATGGAGAGAATGAAATAGATGCAGGAAGACA CTCAAAGGGCCCTTGAAGCTTTGGTTCCTGGCTATGCCCCACCCTTACAATTTTTCTAAA ATTATGTTGTTGACAGGTGACACATGACCTGCAAATAACTTCAGCCATCTTTTAAAATTT TCCCCATCAATGTTGATTTGAGATAGTAACCAATTTTTCTGTACCATAAGGAGTAGTTTC ATGGAGAAATGTAGCTAATGTTCATTTGAAATCATCTGAGGCCACCAGCCTGGTTGGAAG GATTAGAGATTATGTGTGTGAAGGGTGTAACCAGATTTTTTTCTATTCTTCCTCTTTAAA ACAAGAAACTAAAAATTGATATTTTGTAATGGCCTCTTTGAGATTTATCTTTTGAGGGTT TACTTGGAATCATAACCTTGATTAAGGCTTCTTATTAGGAAATGCTGCTGGAGCATTTCT TTAGCTTACAAAGTCTCTCTTTCTACATGGGCCTCAACCTTTATAGTAGCTCCCTTTCCA CATAGTAGGGCTGCACCTAAAGTTCCTTAATTTGTTCTTCATTTTTGATGGGGATTCCAT CCGAGATCTTTTGTTTGCAAAGCATGCTCAAACCTAGTTGGTCAATTAGGTACTTCTGGT ACCTAATTGACCAGCTCTACCAAGTGCGAAAGCTGTCTGCTGAGTTTTATTTTATTTATT ATTATTATTTTTAAATTGACAAGCAAAACTTAAATATATTTATGATGTACAACGTGAAGT TTTGGTATATGTAAGATATTTAACATATGCATTATTTCACACACTTATTTCTTTAGTGAG AACACTTCATTGTCTGGATGAAATTGCTGTATGTTCTCAGTCAGTAGTAATGTCTGTATT GCAGGAGGAAACATGAGGTCAAATAGGGAGCCTAGAACTAGTTCAGGAGAAGTATTGACA AGTTTTGCAGTGACAGCTATTGCCCTATAATAAGTGCGATAAACTTCTGTGACCAGGTCA AGGATGAGGCTGCAGTAAGCAATGGGTTTTGAAGGTTCCCATGGAGTTAAAATCCCAAGG GTATGTCTAGATTGCTCATGCCACGGTTACATTTGCACATTCCTTAGCTCTCAAATGTTA TTGAAAAATATTTTTTACATTATCCCAAATACACATATTCTCCACGTTTGAGTTATGGTC CAGTTAGTTTTTTTAATTTTTATTTTATTTTAATTTTTTTTTTTTGGAGATGAGGTCTCC CTCTGTGACCCAGGCTGGAGTGCAGAGGCATGATCTAGGCTCACTTCAGCCTCTGCCTCC CGGGCTCAAGCAAACCTTCAACCTTAGCCTCCTGAGTAGCTGGGACTACAGGCATGCACC ACCATACCTGACTAATTTTTGTATTTTTTGTAGTGACGAGGTCTCACTATATTGCCCAGG CTGGTCTCAAACTCCTGGGCTCAAGCAATCCACCTACATCAGCCTCCCTCTCGAAGTGCT GGGATTACAGGTGTGAGCCACTGCACCAGGCCATCCAATCAATTCTTATGGGAAGTATTT CAGGTATGGCTATTAGGAGACTTCACCCAACTTTTGGGGCTATTTTCTGACCTTCCGGTT TATTGTGAAAGAAGAATCCTCAGTACCTTGCTGGATAAGTTCAATTGGCTTTTTCTGTCC AGGATTTAGCATCTGAGTTTCTGATCAACATTTGTATAATTTGATATAGCTCAGGTAACC CTGGGGTCATATGTGCCCAGGTCAACATCAACTCAGAGACTAACAAGGTGAGAAGAGCCC AATGAGCTTAGTTGCTCAAATGGAAAGAGTTCAATCAAGAATGGTTATTCAGTCTGGGCA CGGTGGCTCATGCCTGTAATCCCAGCACTTCTGGGAGGCCAAGGCAGGCAGATCGCTTGA GGCCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACTCCATCTGTACTAAAAATAC AAAAATTAGCCGTGCATGGTGGTGCATGCCCTGTAATCTCAGCTATTCAGGAGGCTGAGG TGGGAAGATCACTTGAGTCCAGGTGGTAGAGGTTGCAGTGAGCCAAGATCGTGCCACTGC ACTCCAGCCTGGGTGACAGAGCAAGACTGTCTCAAAAAAAAAAAAAAAGAATGGTTCATT CGCGAATTCAGCCAGGGCCAGGTACAGTGGCACTGCCTATAATCTGAGCACTTTGGGAGG CCGAGGCAGGAGGATCACTTGAGGCTAGAAGTTTGAGACCAGTCTGGGCAACAGAGCAAA ACCTCGTCCCTACAAATAATTTAAAAATGAGCTGGACATAGTGGTGTGTACCTGTGATCC CAGCTACTCAGGAGGCTGAGGTGGGAAGATCACTTGAGTTCAGGTGGTGGAGGCTGCAGT GAGCCATGATTGCACCACTGCACTCCAGCATGGGCAACAGAGCGAGACCCCATTTCAAAA ATTAAAAAAAAAAAAGATTCAGGTGCCTTGAACTCTGGTTTCCTCTCCTGTAATGCCACC ATCTTACATGAAGGCCCTCTTTGCATCACCTGGTAGGAATTGAGATTCAGGCTACTGAAA AAAGTCAATACTAGGGCTACTGCTTTTTCTATGAGTAATAAAGTCCTTTGATTTTGGAAT GTTGTGACAATATCCGTAAAATAGGCAGTCTAATTTGTTAGCTTGCAAGTAGAATAAAAT CTCACACCCTTCACAGCTCTTAGGCATCATATTATTACAATTCTAGATTTCCTTTTCCTG CATTCAATTATGATTCTTAGGCAGAATGTCGGTAGTAAGAAAGGTACTATTTATCCATTG AATTGGAGGAACAAGTAGGGCATCCCAGTGGAGGTGACCAATAGAAAGTTGGATATTGCC ATTTCTGGCATATGAGTGGCACTAAAGACAAGGATTTGTGAGAGATAACCCAGAAAAAAC ACGTAACATATATGATATGCTGCAGTCATCTCACATCTGCTTAACATCAGTGAACTGCAT GCATATCTTTCCAATGCTATGTTCAGTGACTTCATCTTGGTATCTTGAGATTGGCCACAG TGAGAGTATTTACACCATGGAAATTAACAAATGCTACAAATCAAGGCTTCCTCCACCCCC ATGAGAGCTAATAGTCATCAACATGCTACAAGAGGATGGTGTAGCTGATACATGATGGCA GCAACTTCCATCATCTATTTTCTTCTTCTGTGAAATGTGAAGAATAATTGTGTCTATGAC ATGGGATTTTTTAGAGGATTAAATGAGAGACTTTGTAAAACATGTACAATAGTAGTCTTG GTACATATTGTATCTAATCAAATCTGAGATGCTACCAAATTGAAAATTTGGCATTCTTTT AGGTCATACTGCCAAGAAAGAAGAAGCAGTTAATTAAATCATGTGTTCTTGCCACATTGA TTTTAAGACACATATCAATTTCAGAGATGGTAAAATGTGAAAAAAAACTCGGTCTGAAAT GAATAAAGTAAGTAGCATACTTTTAACACGCTTCACTAATGGTATATTATCACTTTGAGT AGCTAAAATGTGTGTATGTGTAGTAAAAAAATCATTTGTTTCAGGTTCTACAATTTTAAA TCACCAATATAATCAAAATTTCTATCCATAAAAATGCTCAGAAATCAGATGGTTTGCATT AATGAATGCTCAGCATACAAATAGGTGCGAAAGAAAAAATTGGAAATATGACTTTTTTTT CAAAATAAAACCAGACACAAAATTCAGTGAGTTGTGAATTTCAAATAGTTAAAAACAACA ACAACGACAACAACGAAGATTTAAACATACAAGAAGCATTGGTGGGGCACAAAAATAACA CCTGTAATCATAAACAAGTGAACGCAAAATTAGTTCTCTAAACAATTTATCCACACCTTA GAAAAACGTGAACTTACATGAGAAGCAAAGTACTAAATGTGCTTATTTAACTAATTATAT ATATGTTCTAGAAAAAAAGATAGGGGACTGGTAAATAATGACAAAGGAAGGGAATTGGCT ACAGTGTAATTAGCTCAAGGCTGTGGGCATACATTTATATTGTATAAAGAAAAATTCCTG GAAACAAATGAATCCAAGCTACCAAACTTGGAGAGAGAAGAGAAACTACTATGTTTGCAC AAAATAACTTCAAAGGGAAACAGGGCTTATTTTCTTTTACACCATTGCAACTAAAAAATA ATAGAAGAGCCTACTATAATTAAGTGAAGACTTTACAGCTATTACAGAGAACACAGAGTT TTAAGCAGGCTATAAAACACTATGACTTTTCTGTGAAGAGGGAGGTATGGGAAAAAATGA AAAACAAAACCAAGCCCATAATGACTTTCAGAAAAACTTAACTCTCAACCCCTTGGAAGC AATCTCTAGTTCCCTCTGGGGAAGAAGCCTTCTCAGCATAAGAAGATACAGCTTTGACTC CAGGGCTCAGCCCACTGCAAGTGGGTTCGTTTGCCTAAATGCATACTTGCCAACTGACCA CAGCTGAGGCACTCTGCTGGAAATAGTTTGCAAATCAGTTTCCATACCATAAGGAGTAAC CACTCCCCAAGACCAGTGTAATGGATGTGGTATAAAATTTTGAAGCAGAGTATGTGTTTC TGGCATGTCATTTGGATGTGAGCCTTGGGCAAAGCAGTCTGTGAACCTCAGGATTTTTTT TTGCTTGTTTGTTTGTTTGTTTCTTCAGACAGGGTTTTGCTCTGTCACCCACATTAGAGT GCAGTGGCATGAACACGGTTCACAGCAGTCTTGACCTCCTGGGCTCAAAAGTGATCCTAC CGCCTAATTCTCCTGAGTAGCTGGGACCAGGAGTACGTGCCACCATGGCTGGCTAATTTT TTTATTTTTTAAGGAGATGGGGTCTCATCATGTTGTCCTGGCTGGTCTCGAATTCCTGGG TTTGTGTGAGCCTCCCATCTCAGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACAG TGCTGGGCCAAACTTCAGAGTTCTTATCAACAGTAAACAATAGTGAGACTTGCCTGTCAG GAGTCATAAGACTCCTGAAAAGATCAAGATATATGTTTTAAAAATTATTTTAAAACTGTA AAAATGCTTTATAATAAGAAATGAATTATTATTACTACTACCGCTACTACTCTTATTTGC CCTGCAAATAGCGTATCAATCACCATAGCACTGTGTGATGAACTTGGGACACGATTCTGC ACAAAATGATAGTAAAGGGACATTAAGAATGCTTTGGGAGGCTGAGGCAGGAGGATTGCT TGAGCCCCAGCAGTTTGAGATCAGCCTGGGCAACATAGTGAGACCCTGTCTCTGCAAAGA AAATAACTTTTTTTTTTAAAATTAGCTGGTGCAGTGGCATGGGCCCATGGCCCCAGCTGC TTGGGAGACTGAGGTGGGAAGGTTGCTTGAGACCAGGAGTTTGAGGGTGCAGTGAGCTAC GATCAAGCCACCACACTCCAGACTGAGCAACAGAGCAAGACCCTGACTCTGTAAAAAACA TTTTTTTAAAGATATATTAATATGTCTTAAAAAAAAGAAACAGGTGTTTCAAGATAGAAG TTATGCTTCATTTTCTATTATAAAGTCTAAAGGAATTCCAGAAAAATCATGAGCTTTTAA TTCAGGCAGACAGGAATTTGAATGTGGACTTTACATTTTATTAGCTGTGTGATGGTGGGC AGGTTACTTAAGCTCTCTGAGTTTAGGGAATCCTACCTCATAGGCTTGTTGCAGACATTC CATTGTGTAAAGTGTGTAGCTCAATGAATTCCAGGTCCTCCCTCTGCTCTTAGATACATT ACCTTTTTTCCTTACATTTTTGTGTGGAGCTTTGGAAGAGCTCTGTGGGGTTATGGGTGA TGTTTTATGTAACCCTGTCCCTCTTTTATTTTTTTTTCTTTTTTGAGATGGAGTTTCACT CTTTGTTGCCCGGGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCGCCTC CTGGGTTGAAACGATTCTCCTGTCCTGTCTCAGCCTCCCGAGTAACTGGGATTACAGGCT CCTACCACCACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTG GCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGAG CTGGGATTACAGGCGTGAGCCATCACGCCTGCCCTCATTTTGTTTTCGACACAGCTCAGC ATAAAGCAGTCAAGAGAAACAGTTGCTTTTCTGCTATTTGAGACTACAACATATAAATTA GAGATGAGACCGAAAATCTGCAGTTATGTTTTATGTCACTAGAGCCAAAAGCTTCATTAA CTGATAATGGCATTTATTCCACACTTTCTGTGTGTTAGGCACTGTGTTTTGTTTTGTTGT TGTTTTTCATGAGACAGGGACTATATTACCAACAGTGGTCTTGAACACCTGGGCTCAAGC AATCCTCCTGCCCCAGCCTGCTGAATAGCTGGGATTACAGGCACGCACCAGCTCAGTATG AAGTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCATCCAGGC TGGGGTACAGTGGCCCAATCTCAGTTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATT CTCCTGCCTCAGCCTCCCAAGTTGCTAGGATTACAGGCATGTGCCACCACACCCAGCTAT TTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTTGCCAGGCTGGTCTCGAACTCC TGACCTCAGGTGATCCACTCGCCTTGGCCTCCCAGAGTGCTAGGATAACAGCATGAGCCA CTACGCCCAACCCAGTAGGAAGTCTTAAATGGCTGTTTTCATTTAATCTGTACATAACCC TGCAAGGAAGTATTAATGACCTGTATTCATTCCCCATTGCTGCTGTAACAAATCACCACA CAGTTAGTGACTGAAAGCACCGCAAATGTATTCTGTTGAAGGTCTGGAGATCAGAAGTCT AAAATGGATCTGCAGGGTATGGCATGGCCTTCCTGGAGGCTGTAGGAGAGACTGTTTCCT TGCCTGATCTAGCTTCTAGAGAATACTCACCTCCCTTGGCTTGTGGGCCCTGCATCACTC TGACCTGAGCTTCCGTCATTGCATTTCCTGTCAGTCTCCTGCCTCCCTGTTTGCTGTATT ATAAGAACACCTGTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGG CCAAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCCGGCCAACATGGTGAAAC CCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGGGGCCTGTAGTCCC AGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGAGAGGCGGAGGTTGCAGTG AGCCGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAA AAAAAAAAAAAAAAAAAAAAGAACCGTTGTGATTACACTAAACCCTCTCAGATAATCCAG GATAAGCTCCCATCTTAAAATCCTTAATTCTTAATCATGTCTGCAAAGTCCTTAATTAAA ACTGCAAAATATCTTGCCATGCAAAGTAACATATGTACAGGCTTTGGGAATCCTGTATGT TAAATAGGCACGTGTGCTAGACAGAATGATGACCTGCCTCCACTTCCCAAAGATGTCCAT GGCTTTGGGAAGGGGGTGCAGGTCATCATTCTGCCTAGCACACGTGCCTATTTAACATAT GAGGGAATTCAGGCTTGCACATGGTGCATGAACACTCAAGTTGCACGCTTTGTAAATTAG AACCTAAGTTCTGGGTCTTGAGCCCAGATGGCAGCCTCCATCCTTTACTACATGAGCCTT GGGCCCAGAAGCACACACTGCCAATTTGCATGAACAGATGTGTTTTGTTTTGGGCATGGT TATTACACTGATGGTGGTGACCACATTTGATAAACGTGCATCAGACATAGATTTATTTTG TACATTGTCTCAAGCTCCAGCAGCCATACTTATTACCTATTCTCAGACTGATCACCTTCA AGACAAATTTAGTACCTACTTGGCATTACACCAGCTGTTACAGATAATTAAACAAAGACC CAATTCTTTATCCCTGAGGGAATTTCTAAGACAAACCAGTATGAAAATGCAAAACTACAT GTGTTGGAATAAAGACCAGAGGGGACTGCTGCCCCAACTGAGAAGGACAGTTAACACATT TATTAATTTGAAACTGTTTTATGTGTCTTTTGCCAAGGGGTTAATAACTTACTTCGGTTA CTATATCTTATTTATTATTATTACTTCAGTGAAAATACTGATGGAGATTGATTTCTTGCT TTAAATATTTAAAGCGTGGAGTTTAAGCCCACTTACAGGAATGTAAGAAACAATGACAAA CTCTGCTCAAGCAAATACCTCTAATTTTTCTCACTAGAAATTGGTGAAAACATTTCACCA GCACTGGAGTAGAGAGGGACATGTGAACAAAGTTCAAACCGCACTTGCAGTTGAAAGTGG ATGAAATACATGCAGACATGGATGAAAATATGCCCTTTGGCCTGGAACTCTAAAATCACG TGTCACTGGGCATGGTGGCTCACACCTGTAATCTCAGCACTTTGGGAGGCCGAGGTGGGT AGATCACTTGAGGCCAGGAGGTCGAGATCAGCCTGGCCAACATGAGGAAATCCCGTTTCT ACTAAAAATACAAAAATTAGCCGGGTGTGGTGATGGGCGCCTGTAATCCCAGCTACTTGG GAGGTTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCGGTGAGCTGAGATT GTGCCAACACACTCCAGCCTGGGTGACAGAGCGAGACTCCCACTCAAAAAAAAAAAAAAA AAAAAAAAAGCACATGTCACCATGTCACTCGGGGAAACAACAAACAACAGAACCTTATGT CAGGGAGAAAAAGTAAGCCCTTAGAAACCCTGCAGGTCCCTGTCAATGTCAGTGGGCTGC CCTGTTTTTGCTGATAGTGCCATGTTAGGAAGATTCAGCCCTGGAAAAATACCATATCTC AGAGAAGGAAGCAGTCAGGGAAGGCCATGTGTAAAAAAGAGAAAGTACTCCATCTGTTGT GCAGTTCAAATACTGAGGCCATTATTTGTTCATCTGGTTGATTCGAAGCTTCAGTCTCTC TCTGTGGCTTTCCTTCTTGAGCTCCTTCATGTTTATGGCTTGAAAAATAATTAATGTCCT GCTTTTAACTCCAACATGATGTTCCTGTTTATATACATCCCACACTTCAATTCTATACTC ATAATTCAATTAAGGAATTTATGTCTGGTACAATTTTTGCTTAGCTCTTCATATATTTCA ATAGATGTAATATATAATCTACAGAAAAATAGAGAAGTGATGTAACAAACAGCTTTACTT TGGATGATTACCTTGCGTATCTTGCCAGATCTTAAATGTCCATCTTTCAATCCTTTCTCT ATATGACTGGGATAAAGTGTTCCAAGAGTATTAGCTAATGGCCCACTGGCTTCACTTAAT TTCCTTTGAGAAGATTTATCTTTATTTGTGTCTGTACCAGCAACTGCGTAGTGCCCACAC TGGTTTGTGCAGCACTCTTCTCTTACGCACCATCGACACGATGAGTAATGAACAAAATGT TATTTTTCCTACATGCTTCACTGCTGAAAATAAAATGTCTGTTAGACATTTCCTGAAGAT TTCTTTTACTGTCAGAAATGATTAAGTGATGGAAATTTGCTAATCAATACAAATCATATA GGAGAAACTTTATAAAATATTTTTGCTATTCTGTTTGTGGACATTTGGTCAGGAATGAGA GCTTTAAAATCTAAATATTGATCTAGTCCACTGAGCTGATTAAACAATGCATTGGCCATT CAGGAGGAATCCACTGAGAGCTGATGTGGGGTGCGGGGGATTTGCCTCCTCCATAACAGA GGAAAAATCTTCAGTGTGACACTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTC TGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCCGCTCACTGCAAGCTCCGCCTCCCGG GTTCACGGCATTCTCCCGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACC GCTCCCGGCTAATTTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCGTGCTAGCCAGGAT GGTCTCGATCTCCTGACCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTAC AGGCGTGAGCCACTGCGCCCGGCATTTTTTTTTTTTTTTTTTAAATCAGGTCTCACTCTG TCGCCCAGGCTGAAGTGCAGTGGCATGATCCCGGCTAACTGCAACCTCCGCCTCTGAGCT CAAGCAATTCTCCTACCTCAGCCTTCTGAGTAGCTGGGACTACATGCATGCACCACCACA CCCAGCTAATTTTTGTATTTTGTAGAGACAGGGTTTTGCCATGTTGCCCAGGCTTGTCTG GAACTCCTGAGCTCAAGCAGTCCTCTCGCTTCAGCTGCCAAAAGTACTAGGATTACAGGC ATGAGCCACTACGCTCGTCCTAATGTCTTTATTTTCCTTATTAATGTCCTTCCATGTAAA TGAATATATTTTATATAGCTTCACAGGCAATATAACCTATATAGTTTTGTCGTCTATAAA ACAAGGAAAATAATACTACCTACTTAGAAAGTTGTTGTAGGTATGAATTTTAAAATTTCT TTTCTTTTTGAGGCAGTCTCACCCCGTCGCCCAGGCTAGAGTGCAGTGGTGTGATCTTAG TTCACTGCAACCTCCGCCTCCTGGGTTCAAACGATTCTCACACCTCAGCCTCCCAAGTAG CTGGGATTACAGGCATGTGCCACCACACCTGGCTAGTTTTTTTGTATTTTTAACTGAGAC AGGGTTTCACCATGTTGGCCAGGCTTGAATTTTAAATTTTCAAGCAAAGAATACAGCTTG TTGCCTGGCATACAGTAAGAACTCAATAAATGTTACAATTTTTATCAGCTACTGCCATAA CTTTTATTTTGGCGAGGTATGTATTATATTAAGTAAAGTGTTAAATGACAGCAGTATCAA AACACTCTCTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCA GGCCGGACTGCAGACTGCAGTGGCGCAATCTCGGCTCACAGCAACCTCCGCCTCCCAGGT TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGGTGCGTGCCACCAT GCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGATTTCACCATGTTGGCCAGGATGGT CTGGATCTCTTGACCTGGTGATCCGCCGGCCTCAGCCTCTCAAAGTGCTGGGATGACAGG CGTGAGCCACCACGCCCAGCCACTTTTTTTTCTTTTAAGTCTTGCTCTGTTGCCTAAGCT GGAGTGCTGTGGGACGATCCTAGCTCACTATAACCTAGAACTCCTGGGCTCAAGGGATCC TCCCACCTCAGCCTGCTGAGTAGCTAGGACTACAGATGCATGCCACCATGCCCAGCTAAT TTTTTAAAAAATTTTTCATAGAGCAGGAGTTTTGCTATGTTATCTAGGCTGGTTTCAAAC TCCTGGCCTTAAGCAATCCTTCTGTCTTGGCCTCCCAAAGTTCTGGGATTACAGGCATGA GCCACCACACCCTGCATCAAAACACTCTTTGAACTCGTGCCTTTTTACTATACCACTTAT ATTTTTATAATTGAAAAAAAAAAAACAGAACTAAAATACTTAACAAGCCTGATGGAAGTG TTAGAGTAAAAATTAAATTAAAAAGATCCTCAAATGATGATACAATTTTCCATTAATTTG TCTGGGTAGTCAGTCATGAACTGTTGATTGAATGTCCGCTAAGTGCAAGCTAGAACCAGT GGAATTGGAGCAGGCAAAGTGTGTAAACTGAACACAGCAAGAAGCAGTGGGGCTCCAGCA TCCTCATGATATAGTCTAGTTTACTTTGGTGGGATTAAGAAATCCTGCTTAAATGATAAA TCTTCTCACTAATCAGTAATATACCTTTCAACCCTAGCCATAGAGTTATTTTCCACAGGT TTTAACAAGGAACAAAGATGTCTCTGATGTGCTTTTCATGACTACAGTTTCTATGCCTCA AGGCTTACTACAGTCGAGGAAAATCTTTCCTTCCTTTCATTCTCTCAAGGCTTCAAGCCT TCAAGCCTTTGAAATGAATCAATACTGAATTCATTGACTTAGGCATTCCAACAAAACAAA GAAACTTAACAGACTAGGAAAAGCATTAAAAACATTTGGAATACTTCCACCCTCCCCGCC CCCGCCTCCACTTTTTTCCTATTGGAATTGCAAGAGTATTTTCACTGTAGAATTGCCATT ACGGCCGGGCGCGGTGGCTCAAGCCTGTAATCCCACCACTTTGGGAGGCCGAGGCGGGTG GATCGCGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTTTACT AAAAATACAAAAAACTTAGTCGGGCGTGGCAGCGTGCTCCTGTAGTCCCAGCTACTCGGG TGGCTGAGCCAGGAGAATGGCGTGAGCCCGGAAGGCGGAGCTTGGAGTGAGCTGAGATCC CGCCACTGCACTCCAGCCTGGGCGGCAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAA AAAAAAAAAAAAAGAATTGCCATTGCTTTGCTTGCAAACAAATGAAAAGCCATTGCTATG GTTTGACGAATGATTCCTAAATCAGGCAGCCTTTTGAGCATCAGTAGGCTCAGAGACTCC AGTGCAGCCACGTGGTGGAAGAACATGTATGGACAGAAAAAGGAAAAAAAAGAAAGAACA GGGAAGGGAAGGGAAGGGAAAGGGGAGGGGAGGGGAGGGGAGAAGTGGAGGGGAGGGGAA GGGGGAGGGGGACCATTGCTACGGTTTGAATGGGTGCCCTCCAAAATTTAGGTGTTGCCA ATGTGATAGTATTAAGAAGTGGGACCTCTAAGAGGTGATTAGGCCGTAAGAGCTGCTCCA TCTTTAATGGATTTAAGGTCGTTTAAAAAGAGGCTTCATGCAGCATTTCGCTAGCTTGCC TTTCTGCTTTCTGTGTGAGGATATAGCAAGAAGGCCCTCACCAGACCAAATGCCTTGATT TTGGACTTTCCAGCCTCTAGCACTGTAAGAATAAATGACTGTTCTTTATAAATTACCCTG TTATAGCAGCACAAAATAGGCTGTGACAACTGTCAATCATCCCCTTCCTAAATTCATTTT ATAAATAACAAGTTAGCATTTCACCAATAGATACTAGTTTTTTAAAAAGAAGGTGATAAA ATGGTCATAAAATGACCATACTGGAGCTTCACTGCTTCTTGCTGTGTTTGGATTGCACGC TTTGCCTGCTCTAATTCCACTGGTTCTATCTTGCACTTAGTGGACATTCAATAAATAGTT CATGACTGCCTAGATGGACAAATTAATGGGAGACTATAAAATTCATTTAAAGATATTTCA ACATAATTTTATATATCCTGCTTTCACTCTAAGTTATGAATAGTTTTCATGCAACACATA TACTCAAGTATATTACAAGTTAAATAATATCTGAGTAATTAAAAATATTTAATGAGCTTT CCTGAATATGCAAAACAAACACTTTCACTTTTGCTGTGAGCTTTTAAGCTGAAAAGTTTA TAGCATTTCAGAAAGAAAAATCAGGATAAAATAAGCATATATCTATGGTATTATGTACTT AATAGCATCTGGTTGCTAAATATTTTCTTTTGGCTTCTTGATCAATAAACAGCAGGAAGC TCTGGCTGTCCATTAGAATGCTTTCAGTAGCAAGACAGAAAGCCCAACTCAAACTATTTA ATTATAACAGAACTGGAAAGTTTAAAGGTAGAGCAGCCTTCAGAATGATTTGATTCAGTA GCTCTGTGATAGCAAAGAACCTAGTTAGGGAGACAATCAAAATGTCTCACTTTTTCCTCT GGTCATACTGTTATAATACACACAACCATATAATGATACATCCTGTCTAGAACTAAGCCT ACCAATAGATGGTATGATTTCCAACAAACCCTTAGACCCTCTTAGCCTCAAAAATCTCTA TTCTATCAACTGTTCTCCAGAATAATATTACCTTCACAATACCTTGTTCAAAGAAATTCT TCATGGTAATGGGAACAAATAATTTGGTATCCGAGTATTACTGCTACTTCCACTGCATAG TTATAAGACATAGGGCAAACCATTGACTTCAATAATTTTCAGCTTCCCAAACTGTAAAAT GAAGCTTACAAATAATGTGCTCCTTGATTGTATAAACAATCTCTAACAAAATCCTACAAC AAACATTTTACTGAATTAGAACACCTTAGGAGTGGTCCTTGTATGTCAGGAGCAAGCACA TTTGTTTACCTGTTTTCTGTAATTGCTTTTGCACTACAATGGCAGAGTAGAGAAGCTGCA ACAGAGTCTATATAACTCTCAAAGCCCAAACCATTTACTGTCTGGCAACCTTACAGAAAA AGTTAGCCAACCCCTGCCCTGCAAAAGGAAGGCTTTCATACCAGAGTTGCAGCTTCACAA GAAGCCTTGTTTTTTTTGAATCATTGCCCACCACATATCTTGGGAAACAGGGAAAGCAAC TTTGGAGTATTCATATTTTTACCCAGAGGGTGTCTGCATCCCAATAGAAACAGATGGCCA TTTTAACTCAGATCATTTGAGGAGGGTTTATTTACAAAGGTTTGAATTCAGGAGAATCAT GGAGATTACTACCTGAAGTAGGGTTTGGGGTGCAGTTACCAGGAACAGGGAGAAGAGAAC ATTGTAGAGTTAGAGTTCCTGAGAAAAATGGGGTCTTCCAGTCGAGGGACACAGCCAATT CAAAGACACCTGGTGGGGAAGGAGGCAAGGTGATAAATACCCCGACTTTCGTCTCCTCTT TCTTCTTTTTTTCTTACTGAGGCTCTGCACTGGCTGAACCCAATCAGAATGACAGTGGAC TTGGCAATGATCATTATGGTCCATACCATTCAGGCTCCTGGGCAGAGAGCAACACAAAGA AGGCTGGAACTGGATATGGTGGGGCAAATAGAAGCTATTTGGCATAGAGAGCAATCTTGG AGGTATCACTGAGCAAAATGAAGAAATGTAACGGTAAAACCGATTGTCACTCAGGCTCCT CCTAAAAGGTTCCTAGATGGAATGACACACTGGTAGTAGTGAACACACCTACCATCCAGA TCTTGGTTTCTAAATACCATTGTCACATAAAAAGAACCAGTACTCCTTGGAAAAATGGCT TTCTCTATGGCTGTGACAGGGAAAATACAAGATGACCTGGGCGTATCTTGTTTTGCCAGA AAGTAAGGAAGAGCTCAAAGACTGAAGGGTGCCAGGTATGGTGGTGTGTGCCCATGGTTC CAACTACTCAGGAGACTAAGGCAGGAGGATGACTGAGTCCAGGAGTTCTGAGTTGTAGTG CACTATGCCAATCAGGTGACTGTGCTAAGTTTAACATCAATATGGTGACCTCTTGGAGCA GAGGACCACCAGGTTACATAAGGAGGGGTGAACTGGCTCAGACTAGAAATAGACCAGATC AAAATTTCCTTGCTGATTAGTAGTGGGATGGTATCTGTGAATAACCACTGCATTCCAGCC TGGGCAACATGGCAAGACCCTGTGTCTAAAAGGAAAACAAAAAGATTTAAGGGTACATGT CAAAAGGACATAGGAGTCAGTTTGAAGAAATTCCCACTGGCCAAATCCGGGGCAATTTTG GACAATATTTAACTATTTGTAGTAATAGTTACAGATTGAGGCTGGGTGCAGTGGCTTCCG CCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACAAGGTCAGGAGTTCGAG ACCAGCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGG GGTGATGGCATGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTG AACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGTGCCATTGCACTACAGCCTGGGCA ACAGTGCGAGACACCATCTCAAAAAAAAAAAAAAAAAGTGTTACAGATTAAACCTCAGAG TAAAGTAAATGTATGTGAACACATAGTGATATAAATTTTAAAATGAATGAATAAATGGGG AGAATGTTCTACCTTATAGTAAAAGTATTAAGGCATATTACTACAAAGTACTAATTAACT ATTAATCAGTGAACACAATGTAATCATTAATTAATTTTATAGTGAAGAAACTTGGTGAAC ACATTAACCAAGTGATAAATATTATCATCAGGGCTGGACATGGTGGTTTATGCCTGTAAT CCTAGCACTTTTGGAGGCTTATGCCTGTAATCCTAGCACTTTTGGAGGCCAAGACAGGCA GATCGCTTGAGACCAGGAGTTTGAGGCCAGTCTGGGCAACATGGAGAAACCTCATCCCTG CAAAAAATACAAAAATTATCCAGGTGTGGTGGTGTGCACCTGTAGTCCCAGCTACTTGGG AGGCTGACATGGGAGGGTCACCTGAGCCTGGGGAGGTTGAGGCTGCAGTGAGACATGATT GTACCACTGTACTCCAGCCCGGGCAACAGAGTAAGACCCTGTCTCAAAAAAAAAAAAAAA GTTATCATCAATAATGAAGTACAAGTCCTGTGCCTCCGATGTAATGTAATGAGAAAACCA CATCATTACTTCTATGGTATTCCTTGCAATAAAAAAGCATACATCCTGAAGAAACATCAG ACTTACCCAAACCAGGGGATAATTAAATGGTTAGTAGCCTGTACTCTAAAAATGACAAGG TTTTTTTTTGTTTGTTTCTGTTTTTTGTTTTTTTGAGACGGCGTCTTGCTCTGTCACCCA GGCTAGAGTGCATTGGCGCTATCTCAGCTTACTGCAACCTCCGTCTCCTGGTTCAAGCGA TTCTCCTGCCTCAGCCTCCCAAGTAGCACCACCATACCTGGCTAATTTTCGTATTTTTAG TAGAGATGGTGTTTTACCATGTTGGCCAGGGTGCTCTCCAACTCATGACCTCAGGTGATA CGTCCACCTCGGCCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACCGTGCCTGGCATA AAAATGACAGGTTAATAAGAAACAAAGAAAGTCTGAGAAACAGAACCTGACTGAAGGAAA CTAAATGGATATCATAACAGTCCCTGGGACTGCTCAGGGACTGTAATGGCCCAGATTTGA CACTGGTCAGGAAGCAGGTGGCATTGAACCTTCTCAGAGGCTCTGAAGGGAGGGGGAACA GTAGAAGTTTTGCACCTAGGTTCTTCTTGGCACCACTTCTAAACCAGAGCAGCCTGGGCA ACATAGTAAGACCTCCATCTCTACAAAATAAAAATAAAAAAACTCTGTATTTTTTTGTAG AGATGGGGGTTTCGTCATGTTGCTTAAGCTGGTCTCAAAACTCCTGGACTCAAGTGATCC TCCTGCCTCAGCCACCATGCCTGGCCATACATTCATCTTATTAATAATATACTCTGTGTC TCTTACATGGGTATATATTAATAAATTCTAAGAAGTATATTTCTTGGTCAAAAGGTATGA GTATTCTAAATTTTATTAGACATGGGAAACTTGCCTTCCAACATATCTCATTTTTTAATT CTTAAAGTTGAATTGGCAAATATTGACTCTAGCCATCCTAATCTGTTATCCTTTTAGGCT CCTATGGGTCCATTTTAGATATTTTTGGTTGTGTTGATTTTATTTCTTTTTGCTCCATTA TATTGCTTCATTTCCCCTTTGTTTTTCCTTTATCCCTCTTTGATGACTCATCTTCATGCT ATTCGGCCAGAATCTGGGTCTGGAGGAGTGTGAACCATGGAGGGTTTACATTATAAACAA GACATCGCCTCTCAGCTGCTCATGCACCTGCTCCCTTGGCCTCCTGTGAAAACAGATGTC CCAGAGCAGTTACAAGGCTCTTTCAGGAGAATTTCCTCCAAGAAGATTTTGCAACTCAAA TGTGAAGCCTCTTCAGGACCATAAGTTCCATGGTAAGGACAGCATACTTCATCTGCTTGA AAACTATTGGTTATTGACATGTTATACTATCTAGTATTTATATTAAAATTTTGCTTTTCA GAAAATCCAAGGACTCCAGTTGGATTTTAGGCAAAAATGTCAATATCAGGCCACAAGACA GAGGGTGGAGATAGCATGGAGGAGGGTCTGTTCAGGGACTGTAATGGCCCGGATTTGACA CTGGTCAGGAAGCAGGTGGCGTTGAACCTTCTCAGAGGCTCTGAAAGGAGGGGGAGCAGT AGAAGTTAAGCACCCAAGTTCTTCTTGGCACCACTTCTAAACCAGTTATTTCTACCCCTT TTGTGAATGATTCTCCTCCTTGACTTGCAGAATCACCGGATTCTCTTAGATGTTAGTACT TCCAGCTCTCTTTTCTTACCTTGGAGGCCTGGAAGAAGCTGGCTGCAGTGAAGGTCATCC CTTAAAGGATATTTGATGGGCCCATTGTTCTCATGCTGGGTGGTTCTTTCCATCTGACAG ACTCTCCATCTAACTATTGAGAATGGTGTAGAAGGGCAGGTTTCTGGGAGGAGAGGCCCC CTCTCATTTTCTAACCATTAGCCATGGTTCCACCCTGGAAAGTTCTTGAGATATAGGGAC ATGGCTAAGACTGATCTGCAAAAATGTTTTACTCATCTCTTTTTTTAAAAAAAATATTAC CTCCAAGGTAAGTAGAGTTTCCGAAAAAAAATTTTAAAACAAGTTTTAGAATCTATGCTT TGCTGAAAATGTCCTTGTTTTTTTTATATTTGTCTCCCCACAAAGAATTTACTGGGTTCA TTAAGCACAGCTTTCTAACTGATGTGCCCAAATGGGTTGCCCTAATCTCAATATTGAATC CCTCAGCCCTCGGATAATCAAATGGAGCTGGGACCAGCCTGAGCTCCCAAGATGGCTATC TCTGGCTATGAGCAGAATCTAAATTTGCTATTTAATATGTGCCAAGATGTTTAAAAGTTT GTGAAGTTCCGCCTTTGAGAATCATCCTTCAGCACATTGTTTCTCCCTGATACATATGGA AATATGCTGTAAAGTCCTTCTAACATGTCCCAACAATGTCCTGGAAGTAGCTTGTCTTCT CAGTGCGGCTGGAACTCAGGTAAGTACCCCTGAACAGGGCTGTATCACAACAGCTGCCCC AGCAGCTCATGACTCTGCAATCACTGTGCTATTGTTGGTGCTATTAATATTTAAGCAGGA GGCTTGGTGTAGCTGCCTGCTGAAACCCAGGCAGACTCAAGCCATGTGGCTGATACTCCT GTCCTACTGTCAATGTGGCTAATGCTATTTATGCCAACTCCTCTGCAGGCCACAGTAGTC CTTCTCCATGTCACAGTCTGTTAAAGATTCTCCTCATTGAAAGGCCAGGCACGCTGGCTC ACACCTGTAATCCCAGCACTTTAGGAGGCTGAGGTGGGTAGATGATTTGAAGTCAGGAGT TCGAGACCAGCCTGGCCAACATGATGAAACCCCATCTCTACTAAACATACAAAAAAATTA GCCGAGTGTGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAT CACTGGAACCTGGGAGGCAGAGGCTGCACTGAACCGAGATCGCACCATTGCACTCCAGCC TGGGCAACAGAGTGAAACTCTGTCTCAAAAACAAAAAAAAAGATTCTCATCGAACTGGCT TTCAGATGCACTTGAAAAATCTTTTCCCTGCACTCAAGCTTGCCAGTCAACTGTATTTGT TCCAAGAGGCCCCACTCTAAGACCCTGCACCAACAATCTGTTTTCCCCTCTATGTGGAAG TTCAGAAGCCAGCCCACCAGCCCTGTGTCCTATCCTTTTGGTGAGTTATTCCTCCAGGAT CTTATTGTACTTTCCAGCTCTTTGCTCAGCCCAGTCCAGACTTGTCTTCAAAACACTGCC CCTTAGAAAGAAAGTGAGTGTGTGTGTGTATGTGTGTGTGTGTGTGTTTATAAGGAAGCA AGGAAGCAGCAGGACTTTCTCAAATGTGTTTCTTCCATCACAGGCATTGTTATACCCTTT GCTATCTCATGGATAACACAGTTTATTGGATTTTTTGAGGTTTGCATTTTCTTGGCCTGG GCTTTTGACCTTGCTTTTGGGAATATGTTTAGGTTACACTGCATGTGCTCAAGTGGGAGC ACCATTCCTTGAGGTTTGTACAGAATCTGAACAGCACTATTATTATGAGATTTGGGATCA AAGAGGTGAACTCTTTGAGGAGATCCTAAGGGTTTCCAGCAAGTTATAGAAGAAAGTGTT TTCTTCCTCCTTTCCTTTCTCCTCATTTATTTTTTAAACCAGCTATGTGTTGGCTGATAC GAGTCTGAGTGATGTATGCTTATATTCTAAAACGATCAGAAGGGCAGGTGTTCTTTCATT ACAAATACTTTCTCCAAATGGCAGTGGCCCAGAGAGATAACTGGCCCACTGGGTAATTAT TACCAGAAAGAAGCATTAGATCTCAATTGTTCTTCCTTTCAATTTTCTCCATGTTTATTG CTTTTGATAAGCAGTTGGGTGACTTTTTACTGGTGTATAAATAACCATTTCAAGGCCAGG CGCAGTGAATCACGCCTGTAATCCCAGCACTTTAGGAGGCTGAGGCAGGCTGATCACTTG AGTCCAGGAGTTTGAGATTAGCCTGGGCAATATGGCGAAACCCCATCTCTACAAAAAAAT CAATAGGGCATAAATAAATAAATAACGATTTTACCTAACAGTCTTCCTCATTTATCTACC TTGGAGTTTATTTTGCAGAAATTTTGTGTTGAAAGAAAATGGCAGGAAGTAGAGCTATTC GATGCGGGTTATTTTATGAATGATTTACTAAAAACTGTTGTTGACAAGGAAGTTTCGATA TAGCTGCTTTAAAAATTGTCCAGGGGCCAGGAGCAGTGGCTCATGCCTGTTATCCCAGCA CTTTGGAAGGCCGAGGTGGGCAGATCACCTGAGGCCAGGAGTTCGAGAGCAGCCTGGCGA ACACGAAACCCCGTCTCTATTAAAAATACAAAAATTAGCCGGGCATGGTGTCGGGCGCCT GTAATCCCATCTACTGGGGAGGCTGAGTAAGGAGAATCGCTTGAACCTGGGAGGTGGAGG TTGCAGTGAGCCAAGATCGCACCATTGCACTACAGCTTGAGTGACAAGAGCAAAACTCTG CCTAAAAAAAAAAAAAAGGTCAGGCACAGTGGCTCACGCCTGTAATCCCAACACTTTGGG AGGCTGAGGCGGGTGGATCACCTAAGGTTGGGAGTTCGAGACCAGCCTGACCAACATGGA GAAACCCTGTCTCTACTAAAAATACAAAATTAGCTGGGTGTGGTGTCGCATGCCTGTAAT CCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGATGGAGGTTGCA GTGAGCCAAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCA AAAAAAAAAAAACTGTCTGGGCTAGGCCAGGGGTGGTGGCTCACACCTATAATCCCAGCA CTCTGGCAGGCTGAGGCAGGTGGATCACTTGAGGTCAGGACTTCGAGACCAGCCTGGCCA ACATGGTGAAACCCCATCTCTATTTAAAAAAAAAAAAAAAAGCCCTGTGTGGTGGTGTGT GGCTGTAATCCCACTGTAATCCCAGCTACTCAGGAGACTGAGGCACGAGAATCGCTTGAG CCCTGGAGGTGGAGGTTGTGGTGAGTTGAGATCATGCCACTGCACTCCAGCCTGGGCAAC AGAGTGTGACTCTGTCTCAAAAAAAAAAAAAGAAGAAGAAGAGGAGGAGGAGGAGGAGGA AGAAAAAATTGTCCAGGTTGCCTTCTATGTCACAGGCTATGAAAAAAAAAAAAATCCCAG GCTAAAAATATGGAGTAGAACTTCATATGGGAGCTCTGGAGATTGGCCATCCATTCCTCT CTCCAGTGGACGTGGGTCAGCCTTCTGGTAAGATCTGATTCCCTGTTCATTTCCTTAGCC GTCACAAAAGTACATAACTCTGTCTTCAGACTAATCATCTCTTGGCAAACTAGAATCACT GTGGAGCACATACTGGCCAGTTGCTATATAGCAGCTTTGTATTACCCAACACATAAGGGA ATCCATATCCCTCCAGGGCTATTTGAAGAACATGTAACTGAAAAGCAGGTTAGTTACTTG CCGCATATAGAGTTCAATTAACAAGAGTGAAGTCTGTTACAAAAAAAGTGAATTTATACC CAAGCTAGCTTGGGGAAAGGGGCACAAAACGTCCTGCCTTTAAATGTGCCTCTTCACCTT TAGAGTAGAGAGCGGGCATTTTTATAAGGGAGGGGAGGAAATGAGCAAGGGTGGGATGCC CCTGCTTCCAGGCAGTTATCTACCGGGCAGTTGAGTTGGCGCCTTCCTGGCAGAAGCGAG TTGTAAAAGTGGCCAAGTAGGCATGCTTTTCACATCCCCTCCTAGTGGGTGTGACTTCCG AGGTGACCCCCTGGAGATGGGAGTTCCCTGGGGGCATGCTTTACTTTGCAAATTGATTGT CAGCTCTCGAGGAGAGACCCCTCTTAGAGCTCACAGTTAGACGAACTTGCCCTGTAGGGA ATGTCTGGTGAGGGGAGGGGAAAGGTTATATTTGCATTTCTAAAGGGCTACGTAGGTTAC AGGGAACAGGGGGAAAAGGAAGAGGAGAGAAAATAATAAAATAATTAAATTATCTCGTAG AAAAATGGGGATACTCGGTTACAGAAACACAGTCCATTCACTTTTTCTGAAAGTCTAAAA TCTATCCCTAGACCAAACCAGACCAAAAGAAAGCTGGACCCCATCAAATTGATTGACACA AGGCATACAACGATGTTACACAAAAGGAGGTCGCTAACGCAGATCTGAAAGGTCAGGGAA GCTTTCCAGAGGAAGTGATGTCTAAGGCAGGACCTGAAACACAAGTAGGCATAATAGTAG GCAAAGAAAGATGCAGTAAAAGAGAACCAAGACGTGAGAGAGCGAGCACGGATTGTTAGA GGAACTGAGGACAGTTCAGTGTGGCTGGAGCACCATGTAAGGTAGAGAGTAGCAAGAGAT CAAGCAGGCAGGCAGGCAGGCGCCAGATTATGCAGAAACAACGATGTTGAGTGTCTGAAC GTTGTCCTGATGGCAATAGGAAGCCATTGGAAAGTTTTATATAAAGGGGATGACAGTCTG AGATATGCCTTTTTGAAAAACTATTGTGGTTGCACTGCAGTGATGGAGGGAACAGTTGGA AAAGACAAGACTGGAAGTTGGAAGACTGCTTGCAAAGCTCTCCTAGTCTAGGTGGGAGAC ATCAGTAGATGGAGAGAAACTGTTCTATTGTCAGGAACACCATCTGGGTTGCCTTGGAAT GCCTGCAGTCACAACCTCTCACTTGGTTTTCATGTTCCCTGTTTGCACCGGCATTTGTGT ATTTATAAGGATCACTCAAAGTGGTTTAAAAAAAAAAATGCACAATAGCTAAAGACCACA CAAGTTACAGGCATAATTTTGTTTCCTGGGAGATTTTTGGAAAATAGAAAAGACTCCAGT TTCCCATTTTTAATTTTGTTAATCTGGGGCTTACATTATTCAAAAGCTACAACATGCTCA AAGTTTCATATTATGACAAATTAGGAGCCAGCTTCCATTCCTCTCTCTCTTACCTCTCAC CTCTGGGGAATAATCAAGTCCTGTAAACACTTCCTAGGAAGTGTCTCACAGTCTTCCCAC TCCTCTCTATGCTCCTGCCACTATCACAGTTCAACTTGCATCATCTTTTCCTTCAAAAGA CCCCTAATTGTGTCCCTTCCTTCAGGATTCTGCATTTCTAGCCATTTTCCACTCTACAGC CAGAGCGACCCTTCTAAATGTAAAATGATTATGTTCCCCCATCATTCTTTAAATGTTGAA AATGACCCTTCATCGTCCTTGCAATAAAAAGCAGGTCTCTTGGCTGGGCGTGGTGGATCA CGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGAGGTCAGGAGTTCG AGACCAGCCTGACCAACATGGTGAAACCCCATATCTACTGAAAATACAAAAATTAGCCAG GCATGGTGGCGGGCACCTCTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTT GACCCTGGGAGGCGAGGTTGCAGTCAGCTGAGATGGCCCCACTGCACTCTAGCCTGGGTG ACAGAGCAAGACTCTTGTCTCAAACAAAACAAAACAAAACAAAACAAAAGCAGGTCTCTG CTTCTCCTTCTTCAGACTGAACTTTTACCGCTCTCGTCTTGCATTCTCTGCTAAAGCTTT TCTGAACCCCGTTCTCCCTTGTTATAGCTATACCTCAACTCCACGATTCAAGAAAGCTAT TCCCCCTACTTGGAATGTGGTGTGTGGTATATTCACCTCTTCTTTTGGTTATCTCTTATT CCTTCTCCCAGCTCTCGGTGTTTGTTGTTGTTGTTGTTGCTGTTGTTGTTTTTTGAGACG GAGTGGCAAAATTTCAGCTCACTGCAACCTCTGCCTCCCGGATTCAAGTGATTCTCCTGC CTCTGCCTCCCAAGTAGCTGGGATTACAGGCGGGTGCCACCACGCCTGGCTAATTTTTGT ATTGTTAGTAAAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCTTGACCTC AGGTGATCTGCCCACCTCAGCCTCCCCGAGTGTTGGGATTACATTTGTGAGCCACTACGC CCAGCAGCTCTCAGTCTTGTCTCTTCAGTCACAGTTTTACAATTCCCAGACTTGGCTAAA TCCCCTTGTGATGTTGTTATAAACATCGATAGTTCCCCTATCAGAATCTCCACCACATTG TTAATTTTTTTAAGTGCATCTCCTTCCTGACTGACCATTCTTGTCTTGTTCCCTTCACAT ATTTCCTGGTATAGAGAAGGTTAAAAAAAATGCTTTGAATTAAAAATAAATTATGAAACA ATCTTGAAAAAGAAGAACCAAGTTGGAAGGCCCACACTTCAATTTTAAAACCTACTACAA AGCAACAATAATCAAGACAGTGTGGTACTGACATATGGATGATATTGTGGTGAACCCCTA TTAACCTCAGTTGGGAAGGCACCAGGTTCAAAAGGCCAAAGAGTCCCAGAGCCAGCAAAT GAGACATGGGGTTTTATTAGGGGGATTACATACAGGGGAGAGAATCCAGTGGCAGTGGGC TGGGCAAGAAAACCGCAACCACTTGCAAAAAGTACTTTGTAATTTATACAGCATTTGCAC TTAATACCCTACCCTTAACAATCCACTTGGCAACATTCATTTAACCCATAACTCAGGGCC TCAAGCCCTGTATGGCCCATGTTCCATGAGACTGGCTGGAGATGCAGATGTTACTCACAG ACAAGGAACAAATCTCCAGGTTGGCTATTCCTGAATTCCCTAGCTCAGAACACACATTCA GGTGCATCTGCTATAAAGGCTCATTGGAAGGTTATGCTTGTTATTGCTACCAGGTGCATT TATCCTACGGCTGGATATAGTTCGATGGAATACAGTTGACACTCTGGAAATAAACCCATG ATTCTGTGCTCAACTGATTTTTTAACAACAGTGCAAAGACTATACAATGGGGAAAGAATA TTGTTTTTAATAAATGGGATTGGAACAACTAGATACCCAGACGCAAAAGAGTGAAGTTGT ACTCCTATGTCACATGATATATAAAAATTAACTCAAAATGGATCAAAGACCTAAATGTAA AAAATAAAATTGGCTGGGCACAGTGGCTCACACCTGTAATCACTCCCAGTACTTTGGAAG ACTGAGGCAGGAGGATCTCTTGAGGCCAGGGGTTCAAGACCAGCCTGGTCAACAAAGCGA GACCTTGTCTCTAATAAAAAATTTAAAAATAAGCCGGGCACAGTGGCTCACGCCTGTAAT CCCAGCACTTTGGGAGGCCGAGGCATGCAGATCATGAGGTCAGGAGATCGAGACCATCCT GGCTAACACGGTGAAACCCCATCTCCACTAAAAATACAAAAAATTATCCAGGCGTGGTGG CGGGCACCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATGGCATGAACCTGGG AGGTGAAGTTTGCAGTGAGCCAAGATTGCACCACTGCACTCCAGCCTGGGCAACAGAGTG AGATTCCGTCTCAAAAATAAATAAATTAAAAAAAATAAAAAATATGCAGCCATAAAATAG AACGAGATGGGCTGGGAGAGGTGGCTTACGCCTGTACTCCCAACACTTTGGGAGGCCGAG GTGGGTGGATCACTTGAGGTCAGGAGTTCGAAATCAGCCTGGCCAGCATGGTGAAGCCCC ATATCTACTAAAAATACAAAAAAAAAAAAAAAAAAATTAGCTGGGCATGGTGGCGCATGC CTATAGTCCCACTTACCTGGGAGGCTGAGGCAGGAGAATGGCTTGAACCTGGGAGGCCGA GGTTGCAGTGAGCCGAGATCACGCCATTGCCCTCCAGCCTGGGCGACAGAGCAAGACTCC GTCTCAAAAAAAAAAAAAAAAAAAGAAGGAACGAGATCAGCCGGGCATGGTGGGTGGCGG CTCACACTTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACTTGAGGTCAGG AGTTCAAGACCAGCCTGGTCAACATGGTGAAACCCTATCTCTACTAAAAATATAAAAATT GGCCAGGTGCAGTGGCTCACGTCTGTAATTCCAACACTTTGGGAGGCTGAGGCAGGCGGA TCACAAGATCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTGTACTAA AAATAAAAAATTAGCTGGGTGCGGTGGCACATGCCTGTAGTCCCAGCTACTCAGGAGGCT GAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGATCACACCA CTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTATCTCAAAAAAAAAAAAAAAAAAAAA AATTAGCCAAGCGTGGTGGCACATGCCTGTAGTTCCAGATACTCGGGAGGCTGAGGCAGG AGAATCACTTGAACTGGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGCACCGCTGCACTC CAGCTTGGGCGACAGAGCGAGACTCCATCTCAAAAAGAAAAAGAAAAAAAATAAAAAGAA AGAGATCATGTATTTTGCAAGAACATGGATGGAGCTGGAGGCTATTATCCTTGGCAAACT AACACAGGTACTAAAAAGCAATTAACTCATCTTCTCACTTATAAGTGGGAGCTAAATGAT GAGAACTCATAAACACAAAGAAGGAAACAACAGACACTGGGGTCTACCTGAGGGTGGAGG GTGGGAGGAGGGAGAGGAGCAGAAAAATAACCATTGGGTCCTGGGCTTAATACCTGGGTG ATGAAATAATCTGTACAACAAACCCCCATGACACGAATTCACCTATGTAACAAACCTTCA CATGTATCCCCGAACCTAAAATAAAAGTTTAAAAAATAAATAAAAATAAAAAGTAAAAAA ACTAAAACTATAAAACTCTTACAAGAAAACATATGGCTAAATCTTCACGACCTTGGATTT GGCAATATTTTCTCAGATATGACACCAAAAACATAAGCAACAAAAGAAAAAAACAGATAA ATAGGACTTCATCAAAATGAAAATATTTTGTTCTCAAAAAACACTATCAAGAAACTGAAG ACTCAGAGAATGGGAGAATATTTTTGCAAATCATATATCTGATAAGGGACTTGCAGAACA CTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGT GCAGTGGTGTGATCTCGACTCACTGCAAGCTCTGCCTCCAAGGTTCATGTGATTCTCACG CCTCAGCCTCCCAAGTAGCTAGGATTACTGGCATGTGCCACCACACCCGGCTAATTTTTT GTATTTTCAGTAAAGACAGGGTTTCGCCATGTTGGCCAGGCTGTTCTCAAACTCCTGACT TCAAGTGATCTTCCCACCTAGGTCTCCCAAAGTTCTGGGATTACAGGCGTGAGCCACCAC ACCCAGCAGAACTTTTTTTTTTTAAATTCATATAGCAATAATAAAAAGACAACACAGTTT ACAAATGGGTTGGATAATTTACAAATGCAAAAGATCTTAATAGACATTTTTCCAAAGAAG ATATCAAAATGGCCAATAAACACATTAAAAGATGCTTAATGTCATTACACATTAGGGAAT ACAAATCAAAACCACAATGAAATATAATTACACACACACCAGGAAGGCTATAATCAAAAA GATTAATAATAACAAGTGTTGGTGAGGATGTGGAGGAATCAGAACCCTCATATATTGCTG GTGAGAATGTTAAGTGGTGACACTACTTTGGAAAATAATCTAATAGTTCCTCAAAAAGTT TAACATAGGCCAGGCGTAGTAGCTCACACCTATAATCCCAGCACTTTGGGAGGCTGAGGT GGGCGGATCAACTGAGGTCAGGAGTTCGAGACCAGCCTGGTCAAAATGGTGAAACCCTGT CTCTACTAAAAATACAAAAATCAGACAGACATGGTGGCACATGCCTGTAATCCCAGCTAC TTGGGAGGCTGAGGCAGGAGAATTGCTTGAACTTGGGAGGCGGAGGTTGCAGTGAGCTCA GATCATGCCATTGCACTCCAACCTGGGCGACAGAGGGAGACTTAGTCTCAAAATAAATAA ATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAACTTTAACAT AGAGTTACCATATGATCCAGAAATTCCACTCCTAGAGAAATGAAAACATGTGTCCACACA AAAACTTGTACATGAATATTTATACCAGCAATATTCATAATAGCCAAAGGGTGGAAACAA CCCAAATTGTTCATCAACTAATACATGGATAAACAACTTTGTGTATATTCATACAATGGA ATATTGTTTGGACATTGTCTTAGTTTGCTTTGTGTTGCTAAACAGAATACCACAGATTCG GTAATTTACAAAGAAAATAAATTCATTTCTTACAGTTCTGAAGACTGGGAAATCCAATAT CAAGGGGCTCACATCTGGCAAGGGCCTTTGTGCTGTGTCATCCCCTGGTAAAAGGCAGAA GGGCAAGACAGCATGAGAGAGCAAGAGACTGCACTTGCAGGCATAAGCCCTTTTGTAATT ATCATTAATCAATTCATGAGGGTGGAGCCCTCATGACCCAAACACCTCCCATTAGGCCCC ACCTCCCCACACTGTTGTATTGGAGATTAAGTTTCCAAAACATGCTTTTTGGGGAACACA TTCAAACAGTAGCAGCCATAAAAAGAAATGAAGCACTTATACATGCTACAGTATGAATGA GCCTTGAAAACATTCTGCTGAATGCTGAGAGGCTAGTCACAAAAGACCACATACATGATT TCATTTACGTGAAATGTCCATAACAGGAAAATCTGTAGAGGAGGAAAGTAATAATTTAAC GGCCGGGCACGTTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGA TCACGAGGTCAGGAGATTGAGACCATCCTGGCCAACATGGTGAAACCCCGCCTCTACTAA AAATATAAAAAATTAGCCGGGCATGATGGCGGGCGCCTGTAGTCCCAGCAAGTCGGGAGG CTAAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCCAGATTGTGC CACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCAGTCTCAAAAAAAAAAAAAAAAAA ATTTACCTCTAATCACTGCATTAGCTTTATCTCACAAATTTTGATATGTTGTATTTTCAT TTTCATTCAGCTTAAAATATTTTCCAATTTCCCTTATGATTTCTCCTTGGGTTCTTCTTT TTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTTTGTCACCCAGGCTGGAGTGCAGTGGTG CAATCTGGGCTCACTGCAACCTCCACCTCCTAGGTTCAAGTGATTCTCATGCCTCAGCCT CCTGAGCAGCTGGGATTACAGGTGCCCACCATGACACCCGGCTAATTTTTGTATTAGTAG AGACAGGGTTTCACCATATTGGTCAGGCTGGTCTTGAACTCCTGACTTCAAGTGATCCAA CTACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCGTGCCTGGCCTCTTT TTGGGATATTTAAAAAGGTGTTGCTTAACTTCCAAGTATTTGGGGGTTTTCTGGATAATT TTTTTGGTTTCTTTAAATACAATTATCTTTTGATCTGAAATCATACTATAATTTCAATTC TTTTAATTTATTGATACTTGTTTTATGGCTGAAAATATATTCTATCCTGGTGAATATCTT ATGTATACATGAAAAGAATATGTATTATGTTATTGTTGGGTGAAAAATTCTATAAATGCA AACTGAGTGACTGACAGAGGTTTTGTTTTTGTTTCTTTCTTTCTTTGTTTTTGACAGGAG TCTCACCCTGTCACCCAAGCTGGAGTGCAATGGAGTGATCTTGGCTCACTGCAACCTCCA CCTCACAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCAT GCACCACCACGCCCGGCTAATTTTTTGTATCTTTAGTAGAGATGGGGTTTCACCATGTTG GCCAGGCTGGTCTCGAACTCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTGCT GAGATTACAGGCATGAGCCACTGCGCCCAGCCTTGACAGAGTTTTCGAAGTCTTCTACAT GCTTTCTGATTTTTCATCCACTTTCTTTTTTGTTTGTTTATTTTTGTTTTTGTTCTTTTT TTTTTTTAATGGAGTTTCACTCTTGTCGCCCAGGCTGGAGTGCAGGTGGCGCGATCTCGG CTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCTTCCCGAGGAG CTGGGATTACAGGCGCACGCTGCCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGG GATTTCACCATATTGGCCAGGCTTGTCTCGAATTCCTGACCTCATAATCTACCCGCCTCG GCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTGTTTTCGTTCTT TTTTGAGACACGATTCCACTCTGTTGTCCAGCTGGAGTGCAGTGGCACAATCAGGACTCA CTGCAGCCTCAACCTTCCAGGCTCAGGCATTCCTCCCACCTCAGCCTCCTGGGTAGCTGG GACGATGGGCATGCACCACCACGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGT TTCTTCATGTTGCCCAGGCTGGTCTCAAAATCTTGGGCTCAAGCGATCCACCTGCCTCAG CCTCACATAGTGCTGAGATTACAAGCGTGAGACCCCACTCCTGGCCCACTTTCTATTGAT TACTGAAAATTGAGTATTGAAATTTCTAACTCTAAATGTGGCTTTTTCTATTTCTCCTTT AAGTTCTAACAGTTTTGCTCTATGTTTTTCAAAGTTTTGTTATTGGGTACATACACATTT AAGATTTTAAAATCTTCTTGGGGAATTGAATTTTATCGTTATGAAATCTTCCTTTTATTT CTGTAATATTTCTTGTTTGAAAGCTTATTTCAGGCCTGGCGTGGTGGCTCACGCCTGTAA TCCTAGCACTTTGGGAGGCCACAGTGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAG CCTGGCCAACATGGTGAAACCCTGTCTCTACTGAAAATACAAAAATTAGCTGGGCGTGGT GGTATGCATCTGTAATCCCAGCTGCTGAGGTGGCTGAGGCACAAGAATCACTTGAACCCT GGAGGTGGGGGTTGTAGTAAGCTGAAATCATACCACTGCACTCCAGCCTGGGTGACAGAA CGAGACTCTGTCTCAAAGAATAAATAAATAAATTAGCGATTTAAAAAATTAAGAAAATTT TTAAAAAGAAAGCTTATTTCCACTAGTGCCGTGACTCACGCCTGTAATCCTAGCACTTTG GGAGGCCAACGTGGACAGATTGCTTGAGCTCAGGAGTTCAAGACCAGCCTGGACAATATG ACAAAACCCCATCTCTACAAAACAATACAAAATATTAGCTGGGCATGGTGGTACATGCCT GTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGCAGATCGAGG CTGCAGTGAGCTGAGCTCATGCCACTGCACTCCAGCCTGGGTGACAAAGTAAGACCCTCT CTCTTAAAAAATTTTTTTTAAAATAAAGCTCCTTTTGTCTAATATTAATAGAGCCACTTC TAGATTTATTTTGGTTAGTGCTAGCTTAATATATATTAATATATAATTTCTCCCTTTTAG TTTGTGTTTTTAGAACATTACATTTAATGTAGTTATAAAGTGTTCATGCTAAATATACCA TTTTTTTTTTTTTTTTTTTGAGATGGAGCTTTGCTCTCGTTGCCCAGGCTGGAGTGCAAT GGCACGATTTTGGCTCACCACAATCTCCACCTCCCGGGTTCAAGCGATTCTCCTCCCTCA GCTCCCATGCAGCTGGGATTGCAGGCATGTGCCACCATGTCCGGCTAATTTTGTATTTTT TTAGTAGAGACAGGATTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCTCAGGT GATCTGCCTGCCTCGGTCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCACCTGG CCTAAATCTACCATTTACTGTTTGTCTTCTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGA TGGAGTCTCACTGTGTCATCAGGCTGGAGTTCAGTGGTCTGATCTCGACTCACAGCAACC TCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGATTACAG GCATCTACCACCATGCCTGGATAATTTTTGTATTTTCAGTAGAGATGGGGTTTCACCATG TTGGCCAAGCTGGTCTCAAACTCCCGAGCTCAGGTGATCTGCCCGCCTCAGCCTCCCAAA ATGCTGGGATTATAATAGATGTGAGCCATGGCACCCAGCTACTCTTTCTATCTATTCCTT TTTTGTCACTTCTTTTGGGTAGACAAATTTTTTTTTTTTTTTCTGTGACAGAGTCTCACT CTGCCACCCTGGCTAGAGTGCAGTGGCCTGATCTCGGTTCACTGCAGCCTCCACCTCTCA GGTTCAAGCGATTCTTGTGCCTTGGCCTTCTAAGTAGCTGGGATTACAGGCATGCACCAC CATGCCCAGTTAATTTTTTGTGTTTTTTCTAGAGATGGCGTTTTGCCATGTTGGCCAGGC TGGTCTTGAACTCCTGGCTTCAAGTGATCTCCCTGCCTCAGCCTCCCAAAGTGCTGGGAT TACAGGCGTGAGCCACCACATCCAGCTGAAAATTTTTGTAATTCCATCTTATTTGTACTA TTGACTCATTAGCTGTATCTCTAAATTTTACTTCTTAGTAGTTGCTCTAGGTTTATAATA TGCACTATTAATTTGTTAACAGTCTATCTTCAGATAATATTACACCACTTCACCTGTAGT ATAAGAATTGTGGCTGGGTGCGGTGGCTCACGCCTGTAATCCCAACTCCTTGGGAGGCCA AGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGGGAAACG ACAACAACAAAAAAATTAGCCAGGCATGGTGGCAGGTGCCTGTAATCCCAGCTACTTGGG AGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATTG TGCCATTACACTCCAGCCTGGGCGACAAGAGTGAAACTCCACCTCAAAGAAAAGAAAAGA AAAGAATCGTAATGCCAGGAGCAGTGGCTCATGACTGTAATCCCAGCACTTTAGGAGGCC CAGGTGGGCAGATCACCTGAGGTCATGAGTTTGAGACCAGCCTGGCCAACATGGTGAAAC CCCATCTCCACTAAAAATAAAAAAATTAGGCCAGTTACAGTGGCTCACACCTGTAATCCC AACACTTTGGGAGGCCAAGGTGGGTGAATCACCTGAGGTCAGGAGTTCAAGACCAGCCTG ACCAACATGGATAAACCGCATCTTTACTAAAAATACAAAATTAGCTGGGCGTGGTGGTGC ATGCCTGTAATCCTAGCTACTCAGGAGGCTGAGGCAGGAGAATCCCTTGAATCCAGGAGG CGGAGGTTGCGTTGAACCAAGATTGTGCCATTGCACTTCAGCCTGGGCAACAAGAGCAAA ACCCCATCCAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGGTGCACACCTGTAATCC CAGCTACTTGGGAGGCTGAGGGAGGAGAATACGTTGAACCCTGGAGGCGGAGGTTGCAGT GAGCCAAGATCATGCCATTGCACTCCAGCCTGAGCAACACAGTCAAACTCCAACTTAAAA AAAAAACAAACAAAAAAAGAATTGTACATGAGTATCCTCCCACGTCCTTGTTCCTATCAT TTTTTACCGTGATTGTTATACATTTCATTTCTCCACACTTTATGAGCTTCACAATACCTT GTCACTAATTTATATTTTAAAATTATCTTTTAAAGAATACTAAAAATGAGAAAAAAATTT ATATTCAGCAAAATATTTTCTTTTTCCAATATTTACTTTATTCCTTTGTGTCAATTCTCA TTTCACCTTGGTATCATTTTCCTTTTCACCTGAAAACTTCTTTATAACATTTTTTATAGA GTTAGTCTAATATTAATATCAATAAAGTATATCAGATTATTTTGAATCTAAAAATATTTT TATCCCACCTTCATTTTTTTTTTAAAGAGATGAGGTCTCATTATGTTGCCCAGGCTGGCC TCAAGTGATCTTCCTGCCTTGGCTTCCAAAGTGCTGTGATTACAGATGTAAGCCACTGAA CCCAGCTCCAGCTTCATCAAGAAGTCTTCTGTCGGGCTGGACATGGTGGCTCATGCCCGT AATCCCAGCACTTTGGGAGGTCGAGGTGGTGGATCACCTGAGGTCAGAGTTCAAGACCAG CCTGGCTATCATAGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCATGGT GGCTCATGCCTGTAATCCCAGTTATTCAGAAGGCTGAGGCAGGAGAATCACTTGAACCCG GAAGACAGGGGTTGCAGTGAGCCAACATAGCACCACTGCACTCCAGCCTGGGCGACAGAG CAAGACTGTCAAAAAAAAAAGGAGAAGTTTTCTGTCATTCATTCTTACCTTTGTTCTTCC ATACATAATCTTGCTCCACCCTTCCCTCAATTCTGGTTGCTTTAGGACTTTGTCTTTATC ACTGGTTTTCAGAAATCTGATGAACATGCACATCAGTGCCATTTTCTTTATATTTCTTCT GCTTGGAGTTTTTTGAGGTTTTTTAATCTGTTGGTTTATGGTTTCATTAAATTTAGGAAA TTTCAGGAATTGTTTTTCAAATAATGTTTTTTCCCTTTTCTCCTTATTTTTCTGGAACTC CAACTCCATGTATGTTAGGCAGTTTGATATTGTCTCATAGATCCCTGATAAACAAATAAA TAAGTTTGATTTTTGGGTTTTTTTTTTTTTCCAGTCTCTTTTTTTGCCATGTTTCTTTCT TTTTTTTTCTTTTTTTGAGAAGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTG CAATCTCAGCTCACTGTAACCTCCACTTCCTGGGTTCAAATGATTCTCCTGCCTCACCTT CCTTAGTAGCCAGGATTACAGGTGCCCATCACCACGCCTGGCTAATTTTTGTATTTGTAG TAGAGATGGGGTTTCACCATGTTGGCCAGTCTGGTCTTGAACTCCTGGCCTCAAGTGATC CACCACCTCGGCTTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACTGCGCCTGGCTGCC ATGTTTCATTTTGGATGGTTTCTGTTGTTATGCATTCAGTTCACGCAAAATTCTTTTTCT CTGCAGTGTCTACTCATTTCATCCAGTATATTTTTACTATTACATAGTGTATTTTCATGT CTACAAATTCTATTTTAAAATATCTTCAATTTCTGTCATCATTTTGTTAACGTTTTTCTT TACGTTCTTGAACATGTAAATAATAGCTGTTTTAAAGGTAATTCCATCTTAATTACCATT TCTGGGTCTCTTTCCATTGATTTATCTACAGGTTATGTGTTATATATTCTGCTTTCCATG AATAATAATGTTTCATTGGTTCCTAGATATTCTCAATTTGCATTGTTATATGCTGGGTTT TGTTATACTCCTTTATAAAAATGAACTTTGTTTTAGCATTCAATTAAATTGCTTGTGAAT TAATTGACATCAGTGGGACTTCTGGGATATTAGATATTGTCTTCTCCTTTTTTAAATCTG GGTGCTGGTTATGTGGGTATGCTTATTTTGTAAAATTTATCAAACTTATTTATGATTTGT GTATTTTTCTGTTTATATGGTACATTAACATATATTCAATTTTAATACCTTTATTTTAGA AATGTAAACGGGGCTGGGCACAGTGGCTGACACCTCTAATCTCAGCACTTTGGGAGGCCA AATTGGGAGGATTGCTTAAGGCCAGGAGTTCAAAACCAGCCTGAGGCCAGGCACAGTGGC TTACGCCTGTAATTCCAGCGCTTTGGGAGGCTGAGGCAAGTGAATCACTTGAGGTCAGGA GTTCGAGACCAGCCTAGCCAATGTGGTGAAACCGTCTCTACTAAAAATACAAAACTTAGC CAGGTGTGGTGGCGGGGGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTAGGAGAATTG CTTGAACCTGGGAAGCAGAGGTTGTGGTGAGTAAGATTATGCCACTGCACTCCAGCCTGG ATGACAGAGTAAACTCTGTCTCAACAACAACAACAACAACAACAACAACAACAAACAGCC TGGGCAATATAGTGAGACCCCATCTCTACCAAAAAAAAAAAAAAGTAATTGGGATAGAGC ATTCCCCTTTTTTTCTCTCCACTTTGATTCTCCCCAGAAGATGATGGGAGGCTCAAAGCA TATCAATGCACTCGAAGGAGTGATTCTGGGTAAGTGAGTATGCACATTCTCCCCTACGTA AATCATCCCATGATCTAGACTTGGAGTAGACCAGATTATGGCCTAATATTCAAGCTAATA TCTTCAATTCAGTTTTGCAAATCACAGGATGGATGATTTGTCCCTGTCTGACAGGCTTTG ATGTCTTCTCCTTTATTGATTTGAAACTTAGGAGGTAGAAAGAAGAGTATTTTCTTTTCT TTCCTTTTCTTTTGAGACAGAGTTTCGCTCTTGTTGCCCAGACTGGAGTGCAATGGCACA ATCTTGGCTCACCACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCC CGAGTAGCTGGGATTACAGGCACGTGCCACCACGCCCGGCTAGTTTTGTATTTTTAGTAG AGACGGGGTTTCTCCATGTTGGTCAGGCTGGTTTTGAACTCCCGGCCTCAGGTGATCCAC CCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTAATCCCACCACCCCTGGCGAAAG AAGAGTATTTTCAACAAGACCTCAAATGAAAACAGACATTCTAGTAATAAATGGGACTTG ACATCTTTGACCCCTCCATGTGACTAAAATTTAAGTTTCATTTTAAAACATGAAGATAAT GATATGTCTGTTTCTGAACCACTGGATTGAAAATTTACACATGGATGAGTTCCATAATTT CACATGTTTAATTGGTCATTAAGGCTACCTTAGCAACTGCTACATCAAATGATAGCTTTT GACTGGGCATGGTGGCTCACACCTCCCAAAGTAGTCCCAGCATTTTGGGAGGCCGAGGCA GGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGGAAAACCCCGTC TCTACTAAGAATACAAAAATTAGCCAGGCATGGTGGTGCGTACCTGTAATCCCGGCTACT TGGGAGGATGAGGCAGGAGAATCGCTTGAACCCGGGAAGTGGAGGTTGCACTGAGCCGAG ATCATGCCACTGCACTCCAGCCCAGGCAACAGAGCAAGACTCCGTGGCTGAAAAAAAAAA AAAAAAGTAGCTTTTACAATTCTGACCTATAGAGAGCTTTCTTAAAGCAACTCAAAGGCC AGGTGCAGTGGCTTACGCCTGTAATCCCAACATTTTGGGAGGCCTAGGCTGGTGGATCAC CTGAGATCAGGAGTTTTAGACCAGCCTGACCAATATGGTGAAACCCCGTCTCTACTACAA ATAGAAAAATTAGCTGGGCATGGTGGTACACGCCTGTAGTCCCAGCTACTCAGGAGGCTG AGACAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGACCCGAGATCGTGCCAC TGCGCTCCAGCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGCAAT TCAATAGCATTAAGTAAAAAGTGATACCTTTATGAGCTACTAAAATGTGTATATGGCCAG GCATGGTGGTGCAGGCCCATAATCCCAGCACTTTGGGAGGCTGAGACAGGCAGATCACTT GAGCCCAGGAGTTCAAGATTAGCCTGGGCAACATGGAAAGACCCTATCTCTACAAAAAAT TTTAAAAATAGTAAAAGACAATCTGTATATATCAAATAAAAATTCCCAGCCAAGTATGAA ATTCTCTAAAGCTTTATACATGAAATGTATAACATGTAATTATCCTTTATTATAGCTAGA GTGGGTTTCTCTTATGAATTGTGGTACAATGTCCAAATTTTTGATCTGATCATTTCTGAA CAACAGAAGGAAGACATCAGTGACAGCAACAACATATACAATTTAAACTTTCATATGTAT GGTCTGAATAAGAAAATTACATTTCAATAACAAAAAAGGTGTTTTTTTCAATCACACTGC TAAGTTTTTGAGATATCAAATTGAGTAAAACATGGCCTAACATCTTAAGAAGTTTACAGT CAGGTAAGAACAATTCATTTTTTCATTCAGCAATATCATAGCACATCTGTATTGTGCCAG GGAATTTTCTAAGAGCTGGGGGTGGAGAGGGGTGCACAGTGAGCAAAATCGACAAAGATC CCCATCCTTATGGGAATTTACATTCTCATGGAAAAAATAAACAATAACCAAATAAATATA TATATTGGATGGTAAAAAATGCAACTGAGCAAAAGTAGAAGGAGGATAAAGTGTGTGTGT GTTTATGTGTGTGTGTTGTGTTGGGGAGGACACGGTTGTCATTTCTTTTCTTGGATAGTG GAAAACCTCAATATATTTAGACTTAGTGAGCTGCAATCCACTTATATGATCCCAGTTTTG TTGGCACCACCTAAAGCATCATGGTAGGTCTAGTCTAAAGTATGCCTTCTTCTCTCCCAA GCAAGTTGACCTTGGCCATGTCAGGGTCCCAGAGCTTCTTCACATCTTGCCGGATCTGTC CTGACAACCGCAGTAAACACCAAGTGCTGGTGCCTTCTACCTTCTTTATGACCCACTGGG AAATCAGGGGCAAACTGATAGTGGCACAATGGTTGTTCTTCTTTCTGGAGAACGCTTTTT TAGATTTTGCTTTGTATAACTTACCCATAAACAGTACTTTCACTTTAAGGATTTCAGCTG TATTTAAATACAAACAGGGAGCTGGCTGCAGTGGCCCAAACCTGTAATCCCAACACTTTG GGAGGCCAAGGCAGGAGGATTGCTTGAGGCCAGGAGTTCCAGACCAGGCTGGGCAACATA GAGAGACTCTGTCCTTACAAAATCTTTAAAAATAGCTGGGGTGGGCCAGGCACGGTGGCT CACGCCTGTAATCCCAGCACTTTGGGAGGCCAAAGCGGGCAGATCACGAGGTCAGGAGAT CGAGACCATCCTAGCTAACACAGTGAAACCCCATCTCTAATAAAAACACACAAAAAAGAT TAGCTGGGTGAGGTGGCACGCGCCTGTAGTCCCAGCTACTCAGGAGGCCGCGGCAGGAGA ATAGCTTGAGCCCGGGAGGCAGAGGTTGCTGTGAGCCAAGATCTCACCCCTGCACTACAG CCTGGCGACAGAGCGAGACTCCATCTCAAAAAATAAATAAATATATAAAAATAAAAGAAG TGAAGTGATAGGAATAATATTGGGTTGGTGCAAAAGTGATTACGGTTTTTGCCTTAAAAG CAGTGACATTAGGCCGGGTGCGGTGGCTCACGCCTGTAATCTCAGCACTTTGGGAGGCCG AGACGGGCGGATCCCCTGAGGTCGGGAGTTTGAGACCAGCCTGAACAACATGGAGAAATC CCATCTCTACTAAAAATATGAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCAGC TACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGTGGTGAGC CAAGATCACGCCATTTGCACTCCAGCCTGGACGACAAAAGCGAAACTCCGTCAAAAAAAA AAAAGCAGTAAAAGCAATTACATCAACCTAATAGCAGGGCATGGAAGCTATTTTGCCTGA GTAAAGATTCCCAGCTTTGTACTGGGCAAGTTACTGAACTTCTCTTTGCCTCAGTTTCCC ACTTAAAAATTGAGATAATAATAGTGCCTCTGTTATGGGGATTAAATAAGATAATACATA GGAGAGAGGAGTGGTTCTGAAACTTTAACTTGTATACAGATCTCTTTTAAATGCAGATTC TGGGATGTCCCCAAGAATCTGCATTTCTAACAAGCTCCTGGGGCTGCTGACTCCACTGCT CCACAGACCACACTTCTGTGTCAAGGTTGTAAGGCACGTAGAACACTGCCTGGCACACAG AGTGCGCTGAATAAATTTAACTATGGTTATATTTTCACACAGTTGAGTTGGCAGGGAAAC CAGATTAAAAAGCCAAAAAGTTTCTCTCCTTCTCTATCAGATGTTTCCTGACGATACTGT ATCCTTGAATAGAATTCTACTGCATTCTGAGTTCAAGTATGAATGTGCATATGGATAACA GGTTTTCATTTTTAAAAGCTCTCAATAGCAGCTTGAAGCACTATTCTTGAATTTATGGTT TTAAGCCGTATCAAAGTACCTAATACCATGTGCATTGCAGGCATTTATTTAATACTTGGA TCAAAGAATGTCCAGACTATCTGAATAAATCATCCCTGTAGGAATGAACAGTGCTGCTGG AGTTCGGTTTTATTTAATGTGGTGGCATGTATGCTAAACTACGACTTCAAGAATGTGGCA ATTGTGTTCTAAAATCCAAAGTATGTTACACTAATCTAATTGCTAGAATCTCATGCAAGG CTGACTCTAACCCAACTACTTCCTTCTTCCTGTGCGGCTCAACCCAGACTTTACATGCTA ACAGTGCCCTCTACTGTTCAGCAACCAGTCGGTGCTACTAAATCCAATTCATAAAGCTGC AAAATCAGAATTCAGACAACTGGGTTCACTTACCACACAAACGTAGCTTGCATCTGCCTT TATAGGAGAGAGGGCGGCTGTCAAGGAGCGGTCCATACTGGGAGGGGCTGAGACTGATTT CTGGGCCACCAATGTGAAGCTGACCAGGATCCCCAGAGAGGAGAGAAAAGCTCGTTGTTG TTTTCCTCTGAAGCACT bcftools-1.21/test/csq/ENST00000520795/ENST00000520795.fa.fai000066400000000000000000000000221467060157400215410ustar00rootroot000000000000008 272897 23 60 61 bcftools-1.21/test/csq/ENST00000520795/ENST00000520795.gff000066400000000000000000000025101467060157400211630ustar00rootroot000000000000008 ensembl_havana gene 1 272897 . - . ID=gene:ENSG00000076554;Name=TPD52;biotype=protein_coding;description=tumor protein D52 [Source:HGNC Symbol%3BAcc:12005];gene_id=ENSG00000076554;logic_name=ensembl_havana_gene;version=11 8 ensembl_havana transcript 94944 213048 . - . ID=transcript:ENST00000520795;Parent=gene:ENSG00000076554;Name=TPD52-012;biotype=protein_coding;havana_transcript=OTTHUMT00000379392;havana_version=1;transcript_id=ENST00000520795;version=1 8 havana exon 94944 95095 . - . Parent=transcript:ENST00000520795;Name=ENSE00002095249;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002095249;rank=3;version=1 8 havana CDS 94944 95095 . - 0 ID=CDS:ENSP00000430865;Parent=transcript:ENST00000520795;protein_id=ENSP00000430865 8 havana exon 106143 106258 . - . Parent=transcript:ENST00000520795;Name=ENSE00003683821;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003683821;rank=2;version=1 8 havana CDS 106143 106258 . - 2 ID=CDS:ENSP00000430865;Parent=transcript:ENST00000520795;protein_id=ENSP00000430865 8 havana exon 212872 213048 . - . Parent=transcript:ENST00000520795;Name=ENSE00002102583;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002102583;rank=1;version=1 8 havana CDS 212872 213048 . - 2 ID=CDS:ENSP00000430865;Parent=transcript:ENST00000520795;protein_id=ENSP00000430865 bcftools-1.21/test/csq/ENST00000520795/ascii-art.txt000066400000000000000000000003771467060157400213000ustar00rootroot00000000000000 tscript 213048 exon 212872 213048 cds 212872 213048 213028 213040 213048 AAAGCCCGAGTCCAAGCCCga A------------AAGCCC bcftools-1.21/test/csq/ENST00000520795/ascii-art.txt-l000066400000000000000000000003771467060157400215310ustar00rootroot00000000000000 tscript 213048 exon 212872 213048 cds 212872 213048 213028 213040 213048 AAAGCCCGAGTCCAAGCCCga A------------AAGCCC bcftools-1.21/test/csq/ENST00000520795/long-inside-del.txt000066400000000000000000000003371467060157400223720ustar00rootroot00000000000000213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A 213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A bcftools-1.21/test/csq/ENST00000520795/long-inside-del.txt-l000066400000000000000000000003371467060157400226230ustar00rootroot00000000000000213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A 213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A bcftools-1.21/test/csq/ENST00000520795/long-inside-del.vcf000066400000000000000000000006031467060157400223250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 8 213028 . AAAGCCCGAGTCC A . . EXP=inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A;type=ENST00000520795:81083598-AAAGCCCGAGTCC-A bcftools-1.21/test/csq/ENST00000520868/000077500000000000000000000000001467060157400166555ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000520868/ENST00000520868.fa000066400000000000000000001117171467060157400210230ustar00rootroot00000000000000>8 8:101697944-101735137 TAAACTCATACAGATATAAATAAATCAGTGAACAAATGGAATGTTTGATGGGCAAGCAAA CATTTACATAGTTTCAAAATACCTCCCTACAACATAGTAATTATAAAGAGAAAAATAGCA ACTTTATAGTGGCAGATAACAACTTAATCAAATGCTCAAAACAAACGCCATTGGTAATGA GATAAAACAGAATCACAGGCCACCAGACAGGATGTAATGAGAAGAATGCAATGTCAATTC TGTGATAGTTCCACCAAAATGTATCATTTCAATCTAATAATAAAGAGGTATCGGACAAAC CCAGATTGAAAGATATTCTATTGAATAACTGGTCTATAATGTTCAAAAGTGTCAAGGTCA TGAAAATCAAGGATAGACTGAAGAACTGCTCCAAAGTGAATGAGCAATTCTTACGTTTTA GGCATGACAATGAAATGTAACTCCCGATTTTGAACTAGATCCTTTTGCTACGGAGGACAT TATTGAAGCAATCAAGGAACTTGAGTGGGGCGTGAGGATTCGACGGTGCTGATCGTTTTC ATGGCGGTGTCATGGTTATGGAGGAGAATGTCCTTGTTTCTAGGAAATAAATATGTGTTT GGGTACGATGCATTAGGTTAGCAACTCTCAAATGGTTTAGAAAATAATTTTTTGTACTGC GTTTCCACTTTTTCTATAGCCTTTGTCATTGCTTCAAATTAAAAAATTAAATTCCATTTA TAAAAAAAAAAGCTTAGCACAAAAGCAAGACATTTTGATTTTGCTACTCTGCTGTAGGGG GTTTGGAGGCTTGGATGTGGATATGATTGTTTTGATTTGTTTAAAAATGTAAAACCATTC TTTAGCTGCAATGGACTTAAGTTTCACTTCAGACCTAACTCCCCATCTCACCCTCCACCC CCCTCAATTATGAAGGACTTTTACTTTCTGCTGAATTCTGAGTTAGTTTTTAAGAGGAGC TATTATTTTTAAAATAAGAGCAAGAACAAAACAATGAAGACACCTTTAAAAAATATGCTG TAACTGGGTTAGCCTCTAAGGTGGTGCTGCTTGGTGCCTCCTCATACCTCACCTCCAAAC AATTAAAAATATTATTTTAAATGGTTAAAATTTAAAATATTAATAAACATATAATATATT ATAGTATAATTAAGTATAATATATAATTAAGTATAATCTATAAATATAGTATAATTAAGT ATAATAAAATATACTTAAAATATTAAGTATAACACGACCAGGGGCAGTGGCTCATGCCTG TAATCCCAGCATTTTGGGAGGCCGGGGTGGGTGGATCACTGGAGGCCAGGAGTTCAAGAC CAGCCTGACCAATATAGTGAAACCCCCTCTCTACTAAAAATACAAAACTTAGCTAGGCGC GGTAGCCTGTGCCTGTAATCCCAGCTACAGAGGAGGCTGAAGCAAGAGAATCGCTTGAAC CTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCCAGTCTAGGCAACA GAGTGAGACTTCATCTCAAAAAAAAAATACACTGGACTTTACCCAGATTAAAACCTTATG CTCATCAAAAGATGCCATGAAGAGAATGAATTGACAAGTTGTCTATTAGACATATAGAAT GGGAGACTATATTCAAGATAGATGTATATGACAAAGGACTTGTATCCAGAACATATAAAG AAATTCTACATCTCAGCAATGAGGAGACAAAAACCCAATTAAAAATAACTGGGCAAAAGT CTTGAACAGACACTTCATAAGAGATATGAATGGCCAATATGCAAGAAAAAAAGTGCCCAG AATCCCTAGTCATCAGTAACAGGAACCTTTAAATTAAAAGAGGCTTAAGAGATATGTTGA CCAACACAAATAACTAGACTTATTTAAATCCTAATTCAGACAAATAACATGTAAAAAAAT TATAAAACAACTGGAGATGTATGAACACCCACTGGATATTTTATATTAAGGTATTCTTGG CCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGAAGGCTGAGGCGGGCGGATC ACTTGAGGTCAGGAGTTTGAGACCATCATGGCCAACATGGTGAAACAGTCTCTACTAAAA ATACAAAAATTAGCTGGCCATGGCGGCACACGCCTGTAGTCTCAGCTAATCGGGAGGCGG AGGCAGGAGAATCGCTTGAACTCAGGAGGTGGAGGTTGCAGTGAGCTGAGATCCTGCCAC TGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAGAAAGAAAAAAAGAGAGAGA GAGAGAAAGGAATTCTTACTCATTTATTTTAACTGGGATAATAGTATTGTGGCAATAATT TTAAAAGTCTTTATCTTTTATACACACTTTGAAATAGTTACAGATAAAATGACATGAGGT TTGAAATTTGCTTCAGAATAATCTAGGGACATGTGAATTGGGGGAATGTAAATGAAAGAA AATGAACCAAATGTTGAGAGTTGTTGAAAGCGGGTGATAGGAACATTGGCTTTATTACAT TACTTTCTATACTTTTGTACACATTTGCAAGTTTCCAAAATAAAAACAGAAAAGGGCAAA ACAACAAAAAAAATTGAGAGGAGAAGGGAGAGAGGAAAGAGAAGGGAAAGTAGAATAAGA TCATTGAGTGTTAGATTGTTAGATAGTTGATACTATTAAAAAATTGACAGACCAGATAAT AAAAGGTTTAGTTAAAAAAAAAAAAAAAAAACGGCCAGGCACGGTGGCTCACGCCTATAA TCCCAGCACTTTCGGAGGATGAGGCAGGGGTATCACGAGGTCAGGAGTTCAAGACCAGCC TGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGG CACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGG ATGCAGAGGTTGCAGTGAGCGGAGATTGTGCCATTGCACTCTAGTCTGGGTGACAGAGCA AGACTCCGTCTTGGAAAAAAACAAACAAACAAAAAAAACAGGTGGGCTGGGTAGTTCATG CTTGTAATCCCGGCACTTTGGGAGATTGAGGCAGGAGAGTCGCCTGAGCCCCAGAGTTCA AGACCAGTCTGGGCAACATAGTGAGACCTCATCTCTTCAAAAAATAAAAAATACGTTAGT CAAGCATGGTGATGAGTGGTTGTCTCAGCTACTTGGAAGGCTGAAGTGGGAGGATCACTT GAGCCTGGGAATTTGAGACTGAAGTGAGTAGTAATCACACCACTGCACTCCAGCCCAGAC AACAGAGTGAGACCCCATCTCAAAAAAAAAAAAAAAAAAGTAACATAATTAGAACAAAAA TGCAATCTTTTCTAAATACCAAAAGATGTAGTACATAAAGAAAAACATAACATTACATAT CTAGCAATAAGGTATTAAATGTGTCAAAGGACATGTTTAATACTAAAAGACACAATTAAT AATGGATATGCATACATGAACATACATACACGTATATTTTACTTTATTCAAAATATATAC ATCAGTACATATACTTACATGTACGTATCTCCTATATAAATTACACGTGTGTGTGTAGGT ATATGGAGATATATATCTCCATCCTAAAGCTGGCATCTTACGTAACAGTGAAATACTAGA GACTTTTCGACTAAGGTCAGAAACAAGACAAAGATTCCTACTGTCTCCACTCCTTTTTTT TTTTTTTTTTTTGAGATGGAGTCTGGCTCTGTTGCCCAGGCTGAGTGCAGTGGCGGGATC TCGGTTTACTGCAACCTCCACCTCCTGGGTTCAAGCAATCCTCCCACCTCAGCCTCCCAA GTAGCTGAGATTACAGATGCCTGCCACCACTCCCAGCTAATTTTTGTATTTTTAGTAGAG ACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCTG GTCTAGGCCTCTGTGGCCCAAAGTGCTGCGATTACAGGTGTGAGCCACCACACCCGGCCC ACTAGTATTTACACAACAGGTATTTGACCAATACAATTAGACAAAGCAAAGGCATAAAAA TTAGAAGAAAAGAAAAAGTGAAACTATCTCTATTTGTACATGACATGATAGCACACCTCA GACCCTGGGAAAAAATGATAAAATAAACTCAATTTTAAAAAAATCAATGTAGCAGTATAT AAAAATTAACATACAAAAATCAACACAAGTAATTTTTTTTTCATATACGCAAGTAATAAC CAGTTGGGATATATAATGGTGGAAGAAAAAAACCCATTTACAAAAGTAACAAATAGCTAA AATAGGAATGAAACTTAACAAGAAATGTTCAAAACCTATATGAATGAAACTATGAAACAC TCCTGAAATACCTGAAAGTGAACTTGAGCAAAAAGAAAGACTTCTGTTCTTGCCTAGGAT ATCTCAGCTTCATTAAGATTTCAATTCTAGACTGGGTGCAGTGGCTCATGCCTGTAATCC CAGCACTTTGAGAGGGAGGACAAGGTGGGCGGATCACTTGCGATCAGGAGTTCAAGACCA GCCTGGCTAACATGGTGAAACTCTGTCTCTACTAAAAATACAAAACTTAGTTTGGTATGG TGGCCCACACACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCACGAGAATCGCTTGAAC CTGGGAGGCGGAGGGCTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGCAAC AGAATGAGGCTCTGTCTCAAAAAGAAAAAAAAAAAATTTCAATTCTAAGTCAATATATAA ATTTAATGTGATCCGAATATAATTCTCAAAAAGTTTTTTTTCTGGAGATAGGCAATTGAA ATGATCATATAGAAAAATAAATATGAGAAGATAGCTAGGAAAACTAAGAAGGAAGGGCTC TGAGGAGATACCAGTCCTGTAAGACATTAAACCACATTACAAAGCTGGTATGATAAAGAA TATGGTTGTGGAGCATGAATAGACAGACTAATGGAACAGAGTAGGAACCCCAGAAATAGA CACAACTACAAATAGAAATTCAGTGTATGATAAAGGTGGTACCAAAAGTTACCAGGGAAA AGCTGGGTTTTTAAATAAATGATATTAAAACAACTGAACATGCCAAATCTGTCCAGCTTA GGGAGAAAAGAAGAAAGAAAAACAAACAAAAAACTGGACAGCCATTTGGGAAAAGATAAA ATTAGATCCATTCTTCACACGATCTTTTCACACAAGCATAAACTCCAAATAGATCAAAGA TCTAAATGTAAAAAACGAAACTAAAAATAGTGGAAGAAAACGTGGGCAAATTTCTCCATA AAATGGGTGTAGGAAAAGTCTTTCTCTCATTATGACTCAAAATCTAAATGAAATAAAAGA CTGATAAATTTGACTACATAAAAAAACTTTTGCATGACAAAAAAATCACTGTAAATAAAG TTAAAAGACAAAATACAAATTGGGAGAAAGTTTTCCCGACATACATCACAGACAAATGGT TACTATCCCTAATACAGCACATAAAACTGTCTTTAAAATTTAGGAGGACAAAAAGTCCAA AAACCCAATAGAAAAATGGCCAAAAGGCATGAACAGACAATTCAGAAAGATATAAAAGTG GTCTACATATATATGTGTGGGTCACACCTGTGGTCTCAGCTACTTGGGAGGCTGAGGTGG GAGGATGGCTTGAACCCAAGATGTTAATGTTAAGGCTGCAGTGAGCCATTTTCACCCCAC TGCACTCCAGCCTGCCTGACAAAGAGGGACCCTGTCTCAAAAAAAGAAAAAGAAAAAAAA AGCATATATATATATAAAGATATATATAAAGAGATATATATATAAAGAGATATATATATA CACACACACATACATAAATGTTTAACTTCACTTAGAGAAATGCAGATTAAAATTACACTG GGCCAGGCACAGTGGCTCACACTTGTAATCCTAGCACTTGGGAGGCTGAGGTAGGTGGAT TGTTTAAGCCCAGGAGTTTGAGACCAGTGTGGACAACATGGCGAGACTCCCATCTCAACA AAAAATAAAAAAAATTAGCCAGGCGTGGTGGCATACACCTGTGGTCCCAGCTACTCCAGA GGCTGAGGTGGGAGGATGGCTTGAGCCCAGGAGGTCAGGCTGCAGTGAGCTGTAATCACA CTACTGCACTCCAGCCTGAGTGAGACACTGTCTCAAATAAATAAATAAGTAAAAATAAAT AAATAAATAATAAAATTAGGCCGGGCACAGTGGCTCATACCTGGAATCCCAGCGCTTTGG GAGGCTGAGGCAAGAGGATCCCTTGAGCCCAGTAGTTTGAGACCACCCTCAGCAACATGG GGAAACCCTGTCTCTACAAAAAAATAAAATAAAAATTAGCCAGGCATGGTGGCACACACC TGTGGTGTCAGCTATTTGGGAGGCTGAGGTGGGAGAATTGCTTGAGCCCAGGAGACGGAG GCCGCAGTGAGCCTAGATTGCACCATTGCACTCCAGCCTGAGTGACAGAGTGGGACTCCA TCTCAAAAAAAAAAAAAAAGAAAAAATTGGAGGTTGAATTGAGACTTACCAGCGTGAACT TTTATAACTCTTATATTTCCTAACTCTGAAAGGGCTTAGAAGCAATGTCAAATCAGTTGC AATGAGCACACCTAAAGCCTTATCTTGGTTTTTACTCCTTAGAGGAATGTCTGGTCCCAG AGCTGGGGTAAGGAAAGTTCAAAATAAACCTCGAACATCTTGTTAAGCCAAAGTGAGAAA GTGTTCAAAACATGATGGGAGATTGTTAAATGCACACAGGACCCAATTTGAACGGGTTCC CCCTGGCCAAGTGTGAGAAAATGTGAGCACCAAGCTAAGAATATAATGGATTATAACCCT GGTTATAAAACAGGAATTCTTTAGGTCATACTGATAATCAATCAATCAATAAGTGTGGGA GGTGCCCTTCCTTATACCAACTTATACATGTAAAGGAGTTGTGAAACTGGAAAATCACCA TTCTCAACCATCCTCGTAAACGTTGGTCCAAGCAAGAATAATTAATGAATGCTAAATCTA GGGGGAAAGTTTGGTGAGGAACAGAATATTTATATAGTTTCAAAGTCTCTCTCCACAGAC TGCTAATTAGTTACAAAAGGTAAAACAGTAACTCTTCAGTAGAGAAAACAGACAACATCT TGATCAAAATGATCACCAATGAGGAACAGAGGAACAAAGTGTGCCTCTGGATGTGATACA CTGGAAAAAATACATTATTTGGGTTGGGAATAAGTTAGCTGAAATCTAATCTTAAGGAAA TGTATAACAAACTCAAATTGAAGAACATTTGTAAAATAAGGAGCGATATAATGAAAGCTA ATAAAAGGCTGAGGAACAGTTGCAGACTAAAGAAAACAAAACAAAAACAAACAACAAAAT GCAAAACATGATCCTGGACTGGAGGGAAAAAAATTGAAAAAGTTGAGGTACAAGACTTAT GATTTTCTCAATGTTAAATTCCTGAATGTAATAACTGATTTATAGCTATATAAGAGAATA CCTTTGTTCTCAGGAAATACACAAATAAGATGATGGGGCTAGGCGCAGTGGCTCATGCCT GTAATCTCAACACTTTGGGAGGCCGAGGTGGGAGAATTGCTTGAGCCCAGGAGTTCAAGA CCAGCCTGGACAATGTAGCAAGACCTCCATCTCTATCTATTTATATATATATAAAATTTT TAAAGATAATAAGAGGTAAAGGGAAATGATATATGCAACCTATTCTAAAATGGTTCAGAA AATATATATATATATATATATATATATGAAGGGAACGAAAAAAGTATATGTGGCAAAATG TTAAACATTGGTAAATTTGGGTAAAGGATATATAAAAATTCTGAATATTATTCTTGCAAT TTTAAGTTTGAATTATTTCAATGAAAAGTAAAAAACAAAAGTATGCCAAGTCTTAGTAAT CAGTTTCTAATTTCAGAAATGCATACCCTGAAGAAAAATGGTATCTCATGTTTGAACCAT TCATTCAAGTATTTACTGAATTCATTCAACAAGTATTTACTGAATGTGCCAAGCAGTAAA GCGAGACAGAATACCCCAGTCATGCCCCTACTCTTAAGTGCTCTTACAGAGATAGGCCTG GCTCTATGTGTTTTTTCCAATTTTGCTGGAGTCACCTCATCTAGGATCCAAATATCAGGG GTGGGTATCAATGCAAATCCCTGAATCATCGTCATTGTTTTTATCATTGTAGTTGTCATT ATCGTTGTAGTGTTTTTCTTCTTTAAATAGCAAAACCCCTTCCTAACACTTGAGAAAAGG TGAATTAAGAGAAACGAAGTTATATGTACCTTTGTTTAAAGTCACGAAGTAGTAGTAATA GCATCCATTTCAAGACATTTCATTTTATGAGGACAGTAATTGTTCACATTTTAAGACTTG CTCTGATTTTGCAGAGCTTTTGAAGACATTTTCCCCTTGTTTGGGAATCAATATGAAAAC ATTGATTGTCCTGCAATTATCAATGTTACATTGTCTCTGGAGTTTTTGGCCTTGTTTCAA TGCAATAAATCAAGTTGTAGATTGCTGGTGGCCTTAGCAGAGCAATTATCACTGCAGCAC ATAATATCCAGCTTGCTGCCTTATTGTGATTCAGAGACCTAGTCACAAGCTTGCTTTTTG TCTAAGAGCCAACAACTAAAAACCCAAGTTTCCATCAACAGAAGGAATAAATTGTGGTAT ATTCATACATGGAGTACTATGCAGCCACATAGGAGCTAACTACTGCTACATATAATACGG AGTAATCTCAGACATGATGTTGAACAAAAGCAGACAAGCACAAGTCAATATGTGTGCATT TATTTATATGAAATTCAAAACAGCTACTACAAATATAGGACATAGGAAGAATGTCTACCT TTGGGGAAGGGGGCAAATATTAACTGAGTAGGGACCCAAGGGAGCCCTCTGAGGTACTGG AAATGCTCTATATTTTTATATGAGTGGTTACAGGGTATAATCATTGGTCAGGGCCAGGCT CATGCCTGTAATCCTAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAG TTTTGAGACCAGCCTGACCAACATGGCAAAACCCGGTCTCTACTAAAAACACAAAAAATT AGCTGGGTGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAA TCGCTTGAACCCGGGAGGTGGAGGTTGTAGTGAGCCGAGATCCCGTCACTGTACACCAGC CTGGCGACAAGAGCGAAACTCCATCACACACACAAAAAATTAATTAAAAATAAATAAACA TTGGTCAAAAATCATAAAGCTGTATCAACTGTATATAAATAATTCAATTAAAATATCATG CATAAAATCTGGGTGTAATAAAAACAAAGAATAATTTTTTTAAAACCCAAAGCAAGGCAA GGGGTGATGTTACCAAACTGCCATGTATCAGAGATGTGATTAGAAGGAAATCCTTCAAGG GGAGCTTATTTATGGTACGCTAGATGTCTTCTGGCTCCATTCACACATGATAAATAACAC CACCTCTCCAAGTCCACTGGTTTGTTTCTTCAAGGAAAGAGTTGGAACAGGATCAATGTT TACACTCACATGACACAAAACATCTATGTCATCTCCATCTGAGATCAGATGAAAGCTAAG TTTAAATGACAGTAGTTGTTATTCATTAATATAATTGGTAAAGAAAATATCAAACATTCT TGTCTGCATAAATAGCAAGACAAAAGCAAAATTAAACAAGTTAATAGCACAGACCCTGAA GTCAGAGAGCCAGGAGTTCTAGATGGGGCTTTGCTACTTAAGTGGCAGTGTGTGTTGCTT ATCTGAAAGAAAACATTACCAATTTGTTGGAAAGTTCTTCTTTAGCAGTAGTAATCGGTG TTTTATCCAACATATTTCTTAATAACTGTTGAGAAAAGGTTGAGACATCTTCCCAATTGG CACAGAAGTGCAATACAAGGCCAGAACATTAATTTCACGTTTTATTAAAAATTCATGGTA ATTAAAAGGTTTTCGTTAAGTCTATTTATCAATTCTAAGAGAACCTAGAACAGGAATATG AACAAGCTCAGCAAAATGATCACAAGGCCACTAAAAGAATGTCTGATATTCCCCAGGCAG TCAAAGATGCTCAAAGGAAGAAAAGTATCCTGACTTAGAATTTTATACCCAGCACGGTTA AAGATCTCCTTTTTCTTCTGTTTTTTAACTTTTTTTCTTCTCTTTCAAGACAACTCGTCA CTAGGATTCCTTTTCTTCTAAACAATGACTTTCTCATTCTTTTTGGCTGTCTTAAAATGT GACAACAAAAAAGCATCTTTGCACATTAGGAAGCCGAGGCAGGCGGATCACTTGAGGTCA GGAGTTCGAGATTCGCCTGAGCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAAA TTAGCTAGGCATGGTGACATGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGGGGCAGGAG ACATGCTTCAACCCGGGAGGTGGAGGCTGCAGTGAGCTGAGATCGCACCACTGCACTCCA GCCTGGGTGACAGTGAGATTCCGTAAAAAATACAAATTTAAATTAAAAAAAAGAAAAAGG AACTTTGTTTTTGCTTTATATTTCATGCTTTAATAAACATAAAAATTTGCTGTCTCCCCA TCCCCCACCTCTCAGACTGAAGGTAGTCCAAGTACCTGAGATTTTATGGAGTTTTACTTT TTTATAGTTTATAGGCAGTTTATGCCAAGCCTAAAAGTGTGAACTCTAGTCTGTATGTAG GCTTGGATTTAAAGCCCAGTTCCACCTCCACTTACTATGTGACTTTGGACAAGTCGCGGT TCAGTTTGATGCTTCAGTTCCCTCATCTGTAAAATGGGAATATATTACTGAACCAATTTC ATAGGGTGGTTTTAAGAATTAAATGATATAGTGCAAGTAAAGAGTTTACTTGTTAAGTAA ACACATACATATACTCAATATTAGCAGTTACAAATGTTAATTCCGAGTTGGCTCTGGTAA ATTTTTTAAAAATTGGTTGATTAAAAAACAGGCATATCGGCCGGGCACAGTGACTCACAC CTGTAATCCTAGCGCTTTGGGAGGCCTAGGCAGGATGACTGCCTGAGCTCAGGAGTTTGA GACTACCCTAGGCAACATGGTGAAACCGTCTCTACTAAAAATACAAAAATTAGCCGGGCA TGGTGGCAGGCGCCTGTAGTCCCAACCACTTGGGAGGTGAGGCAGGAAAATCATTTGAAC CCAGGAGACGGAGGTTGTAGTGAGCGGATATCGCACCACTGCACTCTAACCTGGGCGACA GAGCAAGACTCCATCCCCAAAAAAATCACTACTCTATACTTCTAAGAATCTTCTAAGAAT CCCTGCTTCTTTTTAGTGCACATGAGCTTGGTTCCTCAGGCAATTATTTTATAATCTTCA TTGCTGGCCATAATTGCAGTGCCACCAAATTACCACTGCATCACAAATGGATTTGTAAAG AATAGTCACCCATACTTATAAATGATTTGCTTATAAAAATATCTGTTAAAGCCGGGCGCA GTGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTAGATCACCTGAGCTC CCGACCTCAAGACCAGCCTGACCAACATAGAGAAACCCCGTCTCTACTAAAAGTACAAAA TTAGCTGCATGTGGTGGCACATGCCTGTAATCCCAGCTACTCAGAAGGCTGAGGCAGGAG AATCGCATGAACCCGGGAGGTGGTGGTTGCAGTGAGCCAAGATTGTGCCATTGCACTCCA GCCTGGGCAACAAGAGTAAAACTGCATCTCAAAAAAAAAATCTGTTAAAAATATTAAGTT AAAAATTTAAAGGACTTGTTTAGCATATAATCTGGCATTTAATCCATTTTATATTATAAC TTTTTATTCTTAATAGTAAAAATGTCTTCTACTGATTTAAATAGTTTGGGAAATATTAAC ATTTAGGGGCTGATAAAATAATTTTGAATGTCAGGCTGGCCATCTACCTGGCAATACGAA ATAAGCATAATAAAAAATATTCCATGTACCACACATTTTTTTTTTACTTGGGGTGGGGTA TAGAAACAAAAACCCATCACCAATCATAAATCCATCTGTTCACGTATGCCTTATCAATGA TCATGTATCTTGTGGGAACTTTCTGAAAAGGACAAATGTTCCAACATGTAGAGCTTTTTC TCTGCAGAAAAAACATCAGAGCTAATCAAAAGCCCATGTTGTTTCCTTTTCTGGGGATAT TGTCAGTAACAAAGTAAATAAATTGCATGTTTTTCTACCTTTTTAGATAATACAATATTT TGCAAACTTGCCATGATTGTGAGGGTCAAATAAACGAATACTATCTAAAATTTAAAAATT AGGTTATCCTGGCTGGGCGCGGTGGCTCATGCCTGTGATCACAGTACTTTGGGAGGCCGA GGCGGGTGGATCACCTGAAGTCAGGAGTTCCAGACCAGCCTGGCCAACGCGGCGAAACCC GTATCTACTAAAAATACAAAAATCAGCTGGGTGTGGTGGCACGTGCCTGCAGTCCCAGCT ACTCGGGATGCTAAGGCAAGAGAATTGCTTAAATCTGGGAGGTGGAGGCTGCAGTGAGCC GAGATTGCACTACTGCACTCCAACCTGGGTGACACAGCGAGACTCCATCTCAAAAAAATA ATAATAATAAAAAATAAATAAAAATTAGGTTACCCTGCAATTCTGCCATGTATCTCCCTA GCATGTGAAACTAGGTGGTAGAGAAGATACAGCAACAGGAGATGTATCAAAGTGATCTGA GTGTTACAGAAAGTGGTTAACTAAAAACCCTTAAATCTAACTTAGTAGAAGACAGGCTAT ATTTACTGAAGAGGGAGAGTCAGTATGAGGCCTAAAAATAGGAGACAAATAATTCATTGC CAGGCATGATGGCTGACACCTATAAGCCCAGCACTTTGGGAGGCCAAGGCAGGAGAATCG GGAGTTCGAGACCAGCCTGGGCAACAGATCAAGACCTCATTTCTACAAAAGTAATAAATT AACCAGATGTGGGAGTGTAACTGTAGTCTCAGCTACTCAGGAGGCTAGGCGGGAGGATGG CTTGAGCCCAGGAGGTTGAGGCTGCAGTAAGCTGTGATCACACCACTGCACTCCACCCTG GGTGACAGAGCAAGACTCTGTCCCTATAAAAAAAAAAAAAAAAAAAATTCATCGGTGTAG GGCCAAGTGCAGTGGCTCACACCTGTAATCCCAGTACTTCAGGAGGCCAGGAGTTTGAGA CCGGCCTGGGCAACATAGCAAGACCTCCATCTCTACAAACTAAAATATTAGCTGGATGAG GTGGTGAGTGCCTGTAGTCTCAGCTACTTGGGAGACTGAGGTGGGAGGGTCTCTTGAACC CAGGAATTGCAGGCTGCAGTGAGCTACAATTGTGTCACTGCACTCCAGCCTGGGCAACAG AGACCCTGTCTCTATAATACAAAAAATTAAAAAAATTCATTCGTGTAGCACTGGCATTGT CCAAAGGTACGTCTGCCCTGACTGGTTTATTCAAAGATGTCCCCATGACTGGTTAGGTCT CCTAGCAGAGATCCATGCAGATTATCATAGCTGGACAGTGTTAGGCAGTATATTGACCAG CTCCACCCATGGTGCTTCCAACTCGGACTTAGGATTTAACTTTGCTTCCATGACAACTTG TCTAGTGCACTCATTAAACGTTAAGTATCCAGATACTCTTCAAAGTTATATACTTGCTTT CAGCCAGGCATGGTGGCTCATGCCTGTAGTCCCAATACTTTGAGAGACTGCGGCAGGCAG ATCACTTGGGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCGAAACTCTGTCTCTAC TAAAAATACAAAAATTTTAGCCGGATGTAGTGTTGTGTGCCTGTAATCCCAGCAACTCAG GAGACTGGGACACAATAATTGCTTGAACTCAGGAGGCGGAGGCTGCAATGAACTGAGATC GCGCCACTGCACTCCAGCCTTGGTAACAGAGCGAGACTCTGTCTCAAAAACAAAAAACAG ACCAAAAAACAAAGCCATATACTTGCTTTAAATGAATAATCTGGGATCAAGATTTTAAAC CAAAATAATAAGCAATTTTCAAAGTACTCTCCATTAACATCTCTCACATAACCAAAGATA GCATACTATAAACAAGGCACATTACTTAAGCTTATTTCATCTATGCAAGTCTTAGCATAC GTGTTGAAACAAAGAAAAGATTCCAGAAGTTTCCAATTAACCATTATACATCTAGTATCC ATAGAAAAATGTCACCTGTTAGTTTGTGTCAAAACTGTCAAATGATGCAGTCATACACAT GCTTTAAAAGATACACGGTAGCCCAAAAAATGTCAGTTGTCTTGTTCTGTTTTGCATCTC AAATTCTGCTATGAAACTAGGAGTTTCAAACAAACCACTGTGGATTATGAACTACGTTAT TTACCATATACTACAGTCAGTTCTTTTTACTCATAGCAGTTATGTTCTATGAAATCACCA TGGGCCGGGCGCCATGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGAGGGTG ATCACCTGAGGTCAGGAGTTTGAGACCAGCCAGGCCAACATGGTGAAACTGTCTCTACTA AAAATACAAAAATTAGCCAGGTGTGGTGGTGTGCGCCTGTAATCCCAGCTACTTGGGAGA CTGAGGCACGAGAATTGTTTGAACACGGGAGGCAGAGGCTGCAGTGAGCCGAGATCGTGC CACTGCACTCCAGCCCAGGCAACAAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAA AAAAAAAAAAACAAAGAAATCACCATGAACACTGAATTATTAAATACAGGTTGAGTATCC CTAATCCAAAAAGCTCCAAACCCCTAAACTTTTGAGTGCTGACATGACACAAGTTGAAAA TTCCACACCTGACCTCATGTGATGGGTCAGTCAAAACTTTGTTTCATGCACAAATTTACT GAAAATACCGTATAAAATTACATTCAGGCTGTAACATGTATGAAATAAATTGTTTAGACT TCAGTCCCGTCCCCAAGATCTCATTCTGTATATGTAAATATTCCAGAATCCCAAGCATTT CTGAAAAGGGATAATCAACCTGTACTGACAGGGTTAGGTTCCTGTAAGCCTGTGACATTT CCAGCAATTAATACATGACCTTGTTTTATGTGTTTGTTAAGATACCTTAATATACATTAA TACTGAATTCATGTAACTCATGTCACCCATGCCTGAAAAAAAGCCTCCCTAACATCCATT TTCTCCAAAAGGCTCATCTCTTCCTTCTTGTGCTAAGGAACACCAGGTAACACTTCTGCG CTATGCTTGGGGGCCATTTTAAACAGCAAAATCCACCCACAAAAGGCACAAAAATGTCAA GAACATAGCACTCAACAGACCATGAAAGGGATACTCGTCTGGGAAGTGTGTTATCAGGTG ACGCAAACTTTTTGTTGCTCTGCACACATCCATGAAAGCAGCATGCACACTGATTTGGGG GTTACAAATAAATTTTAGTGAGTAGGCAAATTTGTAAATACGGAATCTGCAAATGAGAAT CAACTGTTTCCTTAATTCCTGCAAGAATCCAAATGCCTACTCCCCAAATCTGTTGGCTCT GGCCACTTAAAGTTTGCTCTATCTGAAAAAGCAGACATTTCAGGAACAGATGAATATGAC TTATCTTCGAATCTCACAACAAATACTGACTTCCAATCAATCAGCTACCTAACGTATAAA GCTATGAACCCAACCTGGCACTAGATTTTGGTGTGTGAACTAGTGTGTGAACTTTATAGA TTTGACTTCAAGTGTCTCAAAATAGCCGGCTCTTTTAAAACCTCAAAATTTGAACCATTT TGTATTACAATTTTGAAAAAATATGGTGTTTCTCTGCCTTAACACAATGAAGAAAATCTT TCAAAAAAAAAAATTGTAATGAAGCATCAGCCCCTGAGAGGGTATGTCTGTTGTGAGGCA AAATACAAAATGATCAGGATCCCCACTGGATGCACTGTTCTATGCTAAAGGGTAGGAGGG TGGAGTTTGTATTATCTTGAGTTTCAAAACAAGAAGCCAAAGCGAAAAGCATTCTAGGTA CAGAAGCATCACTAGGCTTCATCAGCATTGAGGGCTGCCACTGTCACAAGCTAGGGTTTT GTTTAGATTTATTTAATCCCGAAGGTTAATAGAATTGTTTGTTTAGCATGGAATGAGATA ACCACACGTTTAACTTAGAAAGCTAACTCTAGCAGTAGTCCACAGAGAATGATCGGTTAG AAATTAAAACCTAAAAGTGTAAACTGCCTGGGTTATCAGTTTTATGCAGATACCCTATAC TCCAGGCTAGATCTTCTAAATCCATCCTCCTAAAAGAACCCCACATCTTCACCTTTAACA AGTACTTTGGGTATTACACTAAAATTAAGCCACAATCATGAACTACCAAATTAAAGACGT TACAAGAATAAGGTTTAAAACTAATCATAACTTTTAACACTTTAATATTAAAATCATACC AAAGCCTATCTTATCTACATCCTCTTCAAGAGTAGCTATCATTGTTTTATATCATGTAAG GGTTTAAGCTAATAATCTCATAGCCTAGAAACCTCAATATAATCATCAACTGGCAGGCCA GGCATGGTGGCTTATGCAGGAATAAGCCTTATGCTTATGCTTGAGCCCAGGAATTCGAGA CCAGCCTGGACAAAATAGGGAGACCCAACCTCTACCCGCAAAAAAAAAAACCCCATAAAC TGGCTTATCTTCAAAAGTGGATGGGTGTCAGTCTTGTACATGAAATATTAAGATCATGTA ACAAATACATGTAACAAATTGTTTCAATAATCCGTATGGAAACCTTAACTCATAAAATGC ACTACAGGAATTGTCTTGTGCCTTTTACATAAAACCAATAGACCCCCTGAACTTAACAGT ACATTTTTCATAAAAGATTCTTATGTCGGCTCAGCACCATTAAGATATTACCTATTTATG CATGGCAATTATAAAGACTTTGAAAAAAAGCAAATCCGTGCACTGTTTAAGGAATTTTTA TTAAAGCAAGAATTTTATAATCCAAATTACGTTTCCTTGCTCAGTTATCAATTCTGTTAC TTAAAACAGAACTGACATTCTGAGCTATTCCACAGTAAAGAATTACAAAATTAAAGAAAG GAATGCTTTAAATTTTTGTACTTTGCTGAAAATTCTTTTTCCCAGGGTCTATAAAACATT AATTTGTTTTTATATTTTACTATTTTTTTGTGTTTTTTTGTTTTTAAATCAATAAGTAAT CTAGGACTAGCATTATGTTTGCTAGACCTGGCATTTGCTCGGTACATAAGGTTCAAAGTT TCCTTTCCTTTTTTTATTTATTTTATATTTTGCAATGTTTTTTTTCCATAATATTTAAGT TTTTCGATGTTTAGATATTTTTCTTCGGTGAAGCACAAGTTTCTTTTCATGGTCCCTGAT CAATCTGTAAATGTTAAAAAAACAAATTAAGACCAGGACTATCACTTGTCAGTAGCAAAT TAAAGCCCTTAGCCAAATGCAATGTGGTTGTTTTTATCCATAGTTTTACTGGAACACAGC CATACCTGTTCATTTGTATACATACTATCTATGGTTGTCTTGACATGGTAACACTGGAAC AAGATCATTTCAGAGATAACACAGTCCTCAAAGCCCAAAATATTTCCTATCTGGCCCTTT ACAAAAAACATTTGCCAATCCCTGGTCCTGATCCTGGCTGCACTACTCAATTTCTTGGGA GTGATGAAAGACAGTAGTAGAGACCCAAGGGCACCACCCAAAAAGGAAAGGTAAAACTAT GAAAGCCAACCTGTGACAGGTCATTTTATATATATATTACTATACAAAATCTGGCAGGGC GCAGTGGCTCACGCCTGTAATTTCAAGACTTTGGGAGGCCGAGGTGGGCGGATCACTTGA GGTCAGAAGTTCCAGACCAGCCTGGCCAACATGGCAAAACCCCAAGTCTAGTAAAAATAC AAAAATTAGCTGGGCACGGTGGCAGGCATGGGCCTGTTAATCCCAGCTGCTCGGGAGGCC GAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCGTCA ATGCACTCCAGGTTGGGCGACAGAACGAAACTCCATCTCAAAAAAAAAAAAAAAAAAAAA CACCACCTGAAAGTCCTGGGATTTTAAAAATCCAACAGTTAACGGGTAAAATTCCTTTAA TTCCTCTATAGTTAGTTCCACTTTTCCTTGAAAAATTAGCAATACATTTAAATGAACTGT AAAATGATCTTTTGCTATGTACATTTCAAAATATGCTCAACAAACTTTATAAAAGATGAA GAAAACAAGCTTAAAACAACAAACCAGAGGGAAAAGCTCACTTTAAACAGTTGGAACACC GGTGGCACTGTTAACTGCTTTCTGGGCAGCCTCTTTAGCTTGGTGGGCTTGTAGTACAGC TACAGCTTCATCAACCTAAAAAAGGGGAAAACAGATAAACTGGTTCAGGAAAGGAATGGA AATAAAGAGTTTCATAATGGTAACATACCAATTCCCAACAAAGATAAGTTTCTTCCCTCA AATGAAAGTATAAATTGTTACACTAAACAACTATATCCATTCAATTTTGAGTTCTATTAC ACCACTATTCTAGAATTATGAATCGCTCCCCTGCACTACTCTTTCCTTGTCCTCCCCACA CTCGAAAAATATTTCTCTTTCTCCACTAGAGAAAGCAGCAGCAGTTGAGAGTATGGCTGT TGGAGCTGATGGGATTTGAAGCCAGGCTCTGCCACTTAAGAGCTGTGTGAGCATTTGGCA AATTATTCAGCCTGTTTCAGTTTACCTATCTATAAAATGGGGATAAATAGCGCCACAGGT TATTATGCAGACTTTACAACTGTACATGGCTTATATATAACACGATGTAAGTGTTCTGTA CAATTAAGTCCCCATAAAAAGCCACGTAATAACTGTGTAAGAGGCAACTTGGTAAATAAA TTTAAATCACCTTAGAACGGAGTGACTCTGGAGACTCGAGCATATGAAGAAGTTCTGAAT TATCAATCTCCAACAACATGCCAGTGATTTTACCAGCAAGAGTAGGGTGCATGGCTTGAA TAAGAGGAAACAGCCGTTCACCTAGGAACAGAAACATTCAAAAACTCCCTTCAATAAAAA AAAGTTTTTAACTGCATTGAATTACCACATTAAACTGGGGTTTAAGAACCATACTTCTGT CTCACGTATATAATAACCCATAATCCACAATTTCATTATGTCTTCATGGGAAGACAGAAT AAAATCTGCCACAAGGCAATTAACTCTTGATATTATCAGCTTGCCAATTAAGCAATGTTA CCATTAGGTTGTTAAATCGGTGTTCAGGCAAAGTCACAAGTTTTCTTCTCATTTGCTTCA AATTCCTTCTCTCAAAAATGTAGTGAGGGCCCATGGTGAGTAATGCCCTACTACCCTATT TATTACTAACAATACATTTTCTTATTGGCTTTCCAGTGGTTTTAATTAGGCAGACCAACT GTACTATCATAATCATTCATGCCAATTCAGATCAATTCCACTGCCCTAGCTGTCAATTGA TTGACCTAGTGCCTAAGTGATTCCTATATTTTCTAGTCTTTCTGAACTGACAAGGTGGGA CAGAAGTACTCACCCAACATTTGCTTTTGCTCTTGAGGAGGGGCAGATGCCAACATGGAA GCAGTCAAAGGTTCCTGACCTTGTACATGAACAGCAGGCTAGACAGAAAATGAGAACTCT TAAGTTTAAAGCACAGAAAAAGATGGCAAATACAAATAGTCATCAATGGACATCTGCTGA AGTGGTAGACTTCCATCGAAACATGAGGTGGAGAAGTTGAGTGAGCGAATTAGAAAGAAG CCAAAGTAGTTATTATATACTATGTATCACAGATACATTTTTTTTCTTTTTGAGATGGAG TCTCACTTTGTCGCCCAGGCTGGAATGCAACGGCACAATCTTGGCTCGCTGCAACCTCCG CCTCCGGATTCAAGCAACTTTCCTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGCATG TGCCACCAAGCCTGGCTAATCTTTATATTTTTAGAGCTGGGGTTTCACCCTGTTGACCAG GCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCTGAAGTGCTGGG ATTACATAGAGGTGTGAGCCACCACGCCTGGCCCATAGCTACTTGTAATAGTTGTTTCAG ACCAGGCGTGGTGATTTAGGATGTGAATTTCTCGCTGCTTGTCCAATTCCAAAAGCGTAA GACATTTTACATACTATCATATTAGCAGAATGTTCCAGATAGGCTAAGCTCTCAAGAATC TATCATGCAGCTGTCTTCACATTTTTTCTTTTGAGACAGAGTCTTGCTGTCACCCAGCAG GGATTACAGCTTGCTGCAGCCTTAAACTCCTGGGCTCGAGCAATCCTCCTGCCTCAGCCT TCCTAGCAGCTAGGACTACAGGCTTATGCCACCACACCCAGCTAGTTTTCTTTGTGGAGA CAGGGTCCTGTATGTTGCCCAGGCTGGTCCCAAACTCCTGGTCTCAAGCAATCTGCCTGC CTCAACCTCCCAAAGTGCTGGGGTTATAGGTGTGAGCCACTGTGCCCAGCTGTCTTCACA CCTTTGATTTCACCCAAGAAATGTGATTTTTATTAAGAAATCATTAAATCCATACCTGTT GCATTGTAACTTGTGGCTGTGCATTAAGATGTTGCTGAGGATTGCGAACTCCTGCAGCAT ATTTATACTGTGGAACGGTGCGGACAGCAGGAGTAGCTGCAGCGGCTGCAGCTGCAGGAC GTGGACCCATTGTCTGTGTTGATGTGTTAGCTAAAAAATAAGAACATTTTGTATTTTTAT CTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCACCAACACGCT GTGTTGACATGACTCGTGGAACCTGTGAAGAAGCTGGTCTCATAGTACTAAATGGTGGTC TAGGAGCAGCTGGGCGGATAGCACCGGGCATATTTTGGAATGCTGCATTTTAAAGATGTG AATATACATTAACTGGGAAAACTTACTGAGTGAAAAGTGTTTATGCTGTCTTCTTCGATC TGAGGTTTGCATAAAAGACTAAAAAGTGACAAAACTTTTTAAAGCTGAGTCTTAACACTT GCCATTTTCCCAGACTCAGAGCATCAATAAGTAAAAACATTAATTCATACAAGGACGAGT ACTTATATGTAGCGACCAGCCCCACAGGGTCGGTGGGCTTCTCCCTGTATGCAGCGACGA GAGAGTGCAGAAATAAAGACACGAGACACAGAGATTTAAAAAAAAAAGACAGCTGGGCAC GGGGGACCACTACCACCAAGACGCGGAGACCAGTAGTGGCCCTGAATGTCTGGCTGCACT GTTATTTATTGGAAACAAAACACAAGGGGCAGGGTAAAGAGTGTGAGTCATCTCCAATGA TAGGTAAGGTCACGTGGGTTACGTGTCCACTGGAGAGGGGGCCCTTCCCCGCCTGGCAGC CGAGGCAGAGAGGGAGAGGAGACAGAGAGAAAGACAGCTTACGCCATTGTTTCTGCATAT TAGAGACTTTTAGTACTTTCACTAATTTACTACTGCTATCTAGAAGGCAGAGCCAGGTGT ACAGGATGGAACATGAAGGCAGACTAGGAGCGTGACCACTGAAGCACAGCACCATAGGGA GACGGTTAGGCCTCTGGATAATTGCAGGCAAGCCTGACTGATGTCAGGCCCTCCACAAGA GGTGGAGGAGCAGTCTTCTCTAAACTCCCCAGGGGAAAAGCAGACTCCCTTTCCCGGTCT GCTAAATAGTGGGTGTTTTCCTTTGACACTTACGCTACTGCTAGACCTCGGTCCGCCTGG CAACGGGCGTCTTCCCAGACGCTGGCGTTACCACTAGACCAAGGAGCCCTTTGGTGGCCC TGTCTGGGCATAACAGAAGGCTCGCACTCTTGTCTTCTGGTCACTTCTCACTATGTCCCC TCAGCTCCTATCTCTGTATGGCCTGGTTTTTCCTAGGTTATGATTATAGAGTGAGGATTA TTATGATATTGGAATAAAGAGTAATTGCTACAAACTAATGATTAATGATATTCATATATA ATCATATCTAAGATCTATATCTGGTATAACTATTCTTATTTTATATTTTATTATATTGGA ACAGCTCGTGTCCTCGGTCTCTTGCCTTGGCACCTGGGTGGTTTGCCGCCCACACTTATA AATATACCTGAAACATAATCATGATAAAATTCTAAGTGCTCCCAGCCTGGCCAACAGGGC AAAATCCCGTCTCTACAAAAAATTTAAAAAATTAGCTGGGCGTGGTGGCGTGTGCCTGTA GTCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCACCTGAACCCGGGAGGTGAAAGCTG CAGTAAGCCAAGACCATGCCACTGCACTCCAGACTAGAAGAAAGAGTGAGACTCTGTCTA AAAAAATAAACTCTAAGTGCTCTTGGAATATAACATACTGTTCCACAGGACAAGACATAA AATACCACGACTCTGATTCTCATACATGATTAAATGGAACGAGACCTTTAAAACTGTGGC CTGACAAAATATGAAATTGGCTGGGTGCCATGGCTCACGCCTGTACTCTCAACACTTTAG GAGGCTGAGGTGGGCAGATGACCTGAGATCAGGAGCTCAAGACAACCCTGGCCAACGTGG TCAAACCCCATCTCTACTAATAATGCGTAAGTTAGCTGGGCGTGGTGGCGGGCACCTGTA ATCCCAGCTACTCCAGAGGCTGAGGCAGGGAGAAATCGCTTGAACCTGGGAGGTGGAGGT TGCAGTGAGCCGAAACTGAGCCACTGCACTCGAGCCTGGGGCAACAGAGCGAGACTCTGT CTCGAAAATAAATAAATAAATAAATAAATAAAAAATGAAGAGCTGTACCTATTCCCAAAA CTTTTATAAAGGGAAATCAAACCACTGTAGACATTACTATCTTAGCACTGCTTTTAAATG CTATAAAAATGAACATCCATAACCACAAATTATGTGAAATGCAATAGTTAACCTAACATT GACATAGAAGAGCTGATTTACCCAATGTGTTATTTTTAACTCAATCCCCAACCTTAATTA AAAGAAAAAAGACTTACGATGAGGTCTGGCACCCTGAGCAGTCCAGCGAGGACTTGGTCT TAGTTGAGCAATTTGGCTAGGAGGATAGTATGCAGCACGGTTCTGAGTCTGCAGGGAAAA AAAGCACATGAGTTTATCAGTTGAAGAAAAAAGCAAATAATGCAATAAATTATATGTACT TTTTCAAAACATTTACCAGGACTTCACACTCAAGCATTTTTTCCTACTCAATCATAATTC CCCTTTCTTAATGTTTCACATTTGCGGGGCGAGGGGCACAAAAAACACTAGAAATGACCA AATACGAAAACCTTCATGGTTCTGGTTGCCTTCTAAAACCTACCTGTGGGATAGCTGCCA TGAAGTAACCTGAAGGAGGTGCTGGCTGGTAGGGGTTGATTACAGGGTTGGGAACAGCTC GTACACTTGCCATTCTCTGCATATACTGGTTAGTGAGGTGAGCCTGGCGCTCTTCTTTGC GCTGAGCTAAAGCTACATACAATGGCTTTGTGGCCACAATTCTACCGTTCATTTCTGTAA CTGCTTTAGTGGCTTCTTCTGGGGAGGAGAAACATACAAAACCAAACCCTTTGCTGCGAC CACCCTCCATCATAACCTATTAAAAAAAAGAAAAAAAAAGTTAACGTAATGGTAGAATGA GGAGCAAAAAAAGAGCGTTACAATTTAGACAATTATAAATCACTGAATCAAATAACTAAA CCCTGTTAATGCTTAATCATCTTGTATTTACCCATTGAGTTCACAATTTTTCCTTAATAC CCAATTATTAAGGGCAAACTACACATATGCATTACCCTAGCCAGGTCAGAGAACTGACAG AAGTGAAGGCTGCACAGAAACTTTTAAAGATTTTAGATACTGAATTTGATTGGATTTTCA ATATTGAAATTTAATTATCTAAATAAATACATCCCAGGCCTACTAAATTGACTTTTGGGC ACCACTGGAAGCATTTCCCAATTAAATTTTGACTATTCTAACAATTCAAGCTGACAAGAT GCTTCACTATGCCTTTGAGAAAAAAGTAGTTGAATCTTACAATACCCACATCTTAAAATA AAAGTTTTTACATTCAAGAGCAGAGGATCCATAAATATTACGGTATAAAGAACACTCAAG AGGAAGGTTCTTCTAAAATTGATTGCAAAGACCTTTTAAATGAGCAATGAAGACTTGCAA AGAACCACTCGCTAGGCCAGCAATATATATAAGCATGCTATAAAACTACATTAACAGTAT GCGAGTGGCATAGGAACAAACGGTAATAAAACAGAGGCCAGAAATATACCCAAGCAATTA TGGGAATTCACTGTGCTAAAGTTAACATTTTAAAGTACTGGGGAAAAAGGACTTTGGGCT ACTCAATACATGACACACTGGGACAAATGAAAAAATGTAGAACTCTTAATTCACATTACA TTGAAAAATCTTAAATGCCAGGTAGATTCTGAATCTGAACATAGAATGTAGAAATAGAGA GAAAACCTTTCTAAGATGACACACACACAAAGTGAGGTCTATAAAGTGGAAAATTCGAAG AAAATATTTCCAATATAAAACAAATGTTTGGCCGGGCGCGGTGGCTCACGCCTGTAATCC TAGCACTTTGGGAGGCCAAGGCGGGTGGATCACCTGAAGTCAGGAGTTCGAGACCAGCCT GGCCAACGTGGCGAAACCCCGTCTTTACTAAAAATACAAAAATTAGCCGGGCATGGTGGC AGGTGCATATAATCCCAGCTACTCGGGAAGCTGAGACAGGAAAACTGCTTGAACCCAGGG GGTGGAAGTTGCAGTGAACTGAGATCACACCACTTCACTCCATCTCAAAAAAATAAAACA AATGTTCCCTTAATCAATAAAAAGACAGACAACCAGCCAGGCACGGTGGCTCACGCCTGT AATCCCAACACTTTAGGAGGTCACCTGAGGTCAGGAGTTGGAAGACCAGCTTGGCCAACA TGGTGAAACCCCATCTCTACTAAAAATACCAAAAATTAGCTGGGCGTAGTGGCACATGCC TGTAATCCCAGCTACCCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAG GCTGCAGTGAGCTGAGATTGCACCACCGCACTCCAGCCCAGGCGAGAGTGAGACTCGTCT TTAAAAAAGACAAAAAAAAAACACCTCATAAGTTTAAGAATTTGTGTTGCACTGCATTAA AAGCATTCTTGGGCCGCATGTGGCCTGCAAGCAGCGGGTTGGACAAGCTTGGCTTAAGCC CAGGAAAGGCTGAGGCTGCAGTGAGCTGTGATTGTGGCATGCCCCTGCACTCCAACCTGG GCAACATAATGAGATCCTGTCTCAAGAAACAGAAAAACATGCATGCTTCATACATTCAAA ATATGCTGATGCACAACACTCAATTTAAACAATATCCAGGGAACACACTGAAGACAAAAA CATTCAGGAATAAATTCTATCGTACTCCAATACTCTTACATAAAAAGCATAATCTGAAAC ACAAGACAACCATGGCACTTCCATCTTACTTGTATTCAACCACCTTTCCCCTAACATTTC CTCACTCTCACAGAAGCTTCCTCGGACTTGCCAGGAAAAGCTGACTAGAAAGATCAGCCA CAGCGTCATTCCAGTTCAGTTGAGTTGTAATTTTTTTCTATGCACTCTTCCCCAACCCCA GCAAAATTATGTATGCACAAAACCTTGCATATAGGGGGACTCTTGGCCCACGGATGCTAG ACAAAAACATCTAGAAGAGAACTTCTTAAATCAAGATTTCAGAATTTGTACTAGAATACT ACTGCTTTGTTTCTTAATCTCTGATTTCAAATAAAAGAAAATATGATCTCTATTCTTACT GCTAGGGGGCAGGGGAGGGAACTGGGGCTTGACTACCCAGAATGAATTGTAGAAATGAAT AAACAGATCAGAACTATAGTAACAATTATAAGTCCCTAATAAATTGCTTGCTTTAGCAAA ATGACTAGTTGTTGGAATAGTGCATATCATGTGAGGATATCAGCCTTCCTTAGCAAAGAG TTCAGTGCTTGCCATTTTTAAGTTAACCATTAGGCTATGACAACCAGTTCAAATGTGAAT TTAAGTTTTAGAAGTAACGAAGCAAACACCTCTCTAGTGGCTATAATAATACAAAATTTA TATACATATATCTACATGTATGAATTTTTACTAGACCTCAAATAAATGAACCATATGTTT TCTTACCTTTGCACTAGTGATTGTACCAAATGGAGAAAACTCTTTCCGGAGACGTTCATC ATCAATACCATCATCAAGATTTTTCACATAAAGATTAACACCCTAAAAAGAAGAAAAGAA AACTATAGAAAAAGAAAACCATGGTGGTACCTAAGTACATCGGGTCTATTATTTTACCCC ATATTTCTTCTCCTATTCCCCTCTCAAACCCTCCAGCTACCTGGAAGTAACTGAAATCAA CGTAAAATAGGTTTCCTCATCCCTGTCTTATTTTGGTTGTTCAATTAAAAATGAACCTGG TATCTGGTGATCCTATCTTGTTTCATCTGTTCAAATTTGCGCTTAAGTTCCGTCTGCCGT TCCACCTTTTTCTGAGCTCGACCAACATAAATTTGTTTTCCATTGAGCTCCTTTCCGTTC ATCTCATCCACAGCCTTCCCCCCAAAAAAAAAGAAAAAAAAAAAATCACAAAACTTTCAA CTTACAGTTCATTTCCTTAACAGTTAAGACAAATTTGTTAAGTCACAAAAGCTAAAGACA AACCCATCCCAAAATCTCAAGGTTTTGGGACAATATAGGTTACCAATTTATACTCTCAAA CCTAATGCATAAAATGCAAATAACTGAAAATATAAGAACATGTCAAATAGCTATTAGTAT GCACATAGACTTCAACACAAGAGCAACTCAACTTTGTACCCCCTTCTTCCTGCTGAATAC AGACCACTTACTTTCTGTGCATCTTCATGCCTTTCAAAGCTTACAAATCCAAATCCTTTG GATTTTCCACTTTCATCAGTCATTACTTTCACACTTAAGGCAGGCCCTAAAAAATTTTTT TACATAAATCAAAGATATTCCATACAACATTCACGTTATACATTTCAAATTTCAACATAC AAAGCCATGAAAAAAATTTCAAAGCTCCGTAACTTGACTCCTCCCTCCCAGCCTTCTATG CCCCAGGTAGGTATACTTTTCCATTGAAAGACCTTTTATTATTAAGAAGGTAAACACCTT CCCTCCCCTGAAGGATTCCTCCTTCCATTTAAGGAGGTACACTTTAAACGGCTGTAAAAA GTTTTATTCTCAGCTCTAGCACAAAAGAGTTGCATTTTTTACCCAATAATTTGATTTTTT CCCTTTTCTATAGAGACAGTATATCATTCCATTGCCCAGGCTGAAGTGTAGCAGCACAAT GAATAAGCTCACTTTAACTCAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAACTTACCA AGTATCTGGGACTACTGGCCCACATACCACCATGCCTGGCTAATTTATTTTTTGTAGAGA TAGGGTCTTGCTATGTTGCCCGGGCTAGTCTAAAACTTGTGGCTTCAAGTATCTTCCCTC TTTGACCTCCCCAAGCGCTAGGGTTACAGGCATGAGCTATTGTGCTAAGACCAATTTGAT TTTCTTTGTATCAATTAAGAAACAAGTATTTATTAAGCCTTGGCCTACCCGACTTTCAAC AGGAGTGGAAGGAATACATAGTTGGACTCTTTGGTAAGACATAGGTAATACAGGAATTTG AAAGACAGGGAAAAAAAATTCTTTTTAAAGACACAGGTGAACTACCTGGAAGAGGAAGCA TTTATTTCTGAAGACATGTTTTCCCCTAACTCCCTCTAAAGTAGGAGAGACAGGTAACTG AGGCGGGTGGTATCTCAGGCAAGTGGGGCAGAAAAGGTTAAAAATCACATTTGATTACAG AAATTTAGAAGATGTATGGGCCAAGGCAGATTTTCTTCTGAATGTGCCTCTCTCCTGAGG CCAAAGTCAAGAAAATATGACATATTCACATATTTGTGGTCAACTTATGCAGCATTACTC ATACGGTAGGTAGTTAACATCAACTTTTACAAACAGCTTCTAATTATAAGACATTAAGAA GCATGACAGTTGAAATATATAAAAGGCAGTAGCTAAATTTGGGGGTTGAGATGTAAACAT GATGTCACTTTCTATGTTTTATATCATCTATCTTTGTGCAAAATGGTACTTTTTTGCTCT AGTGGAGGGCTTGATGTGACATGCTAGCATGGCAGTAAGATATTAGATTTCCTGGCCAGG CACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGCTGGATCACTTG AGGTCAGGAGTTGGAGACCAGCCTGGCCATCACGGTGAAACCCCGTCTCTAATAAAAATA CAAAAATTAGCTGGGCATGGTGGCGCACACCTGTAATCCCAGCTACTCAAGGTAGAGATA GGAGAACTGCTTGAACCCGGGAGGCGGAGGCTACAATGAGCCGAGATCACGTGACTGCAC TCCAGCCCGGGTGACAGAGCAAGAGTCAAAAAAAAAAGTATTAGATTTCCTAATTCTTTA TTATTTGACATATTAAAAAAAGCAAGACACCTCTAAGTTCAACACAAAATGCAAAGGGTG GGGTCAAGCAAATCATCTGCACATGAACACTTAAAAGTTATTTTATCTGTTATACCCCTA CCTAAACTAAGGCTGGTTTGTGCTTCATCAATTTCAAGTTTTATGAAGTTATTTTTAAAT GCAGGAAATAAGTACTTTGAATCACTGGAAAATCTGAATTTTTGGTTTCATCGCTGAAAG TCATTGTTTTAAACTGCTCAAACATGATGTTACTTAGACTGACCAGCTTTATTGTTCTAT GAGACTGCATTCCACTGTAGGCTGGCTGTGTCAAATATATGCTTCTGATGACATGGGATC TCTAATTACACACACACACACACACACACACACACACACACACATATATATCTCCAGCCT CTTAATGTAGTAAAATATTTTAAAATCTGTTCTAATTACTTAGTCATACCTTACTGTGCT AATCTAATGCTATTAACCTTTAACCTGGATAGAATTCTATTTATTTGCATTATACTACTT TGTAGTGTAATAGATGGCCAGCAGCTTAATTCAAATAACCACAAATATTTTAAAGTACCA TGTAAGTCTAATTTTATTGACTTTTTTAGTATAAAGTAATAGCTAAAATTAACACTGAGC ACTAATTCAGAGCTTTGTGTGTAAAAATTTAATTAAGACACATTACCAAACTTGCCAAAG AGATCCTTAAGGCGCTCATCATCCATGTCTTCTCCAAAATTCTTGATGTAAACATTGGTG AATTCTTTTGCCCTAGCTCCAAGTTCAGCTTCTCGTTCTTTACGAGACTTAAATCGTCCA ACAAATCTAATAAGATATACAAGGACTATAACATTAGATTCTATTTTATAAAGTTCAGAT TAAGTAAGCCTGATGGTTGGTTTTGTTACTGTTAATGAGAATATTCAGAATCCCTAATAA AAAGCACACTACAAAATAGAAATAGGGCCATAATTTAAGATATGACACCATGAAATATAT GAATAAGCCTCTAACTACAATCACAAAAAAAAAACCACTTCTTTTAATACACACTTCTCT TCTCTAGCTAACCTAGGGTTAAAGGGATCACTCCCATCAATACAAATGAGTGGAAGTGCA TGTGTACCATGCCAATAAAAAGACCTCTATCAAATTAAAAAGCTTTCATCGTCATTTTAA AGTGGCGCTTGCGCTTTCTTTGCCATCTCCTAGAATAAAAATTTAAACTTCCCAATCGTG TACTCTAACACACAACAGCCTGACATAACTGCAGCATTTTCAACAAAATGACACTAAAAC TTAATTTTTTCTGAATATAACAGTAGTAATTCAGAACAAGGATCACTGGGCTAGGCAGTG GCTCACACCTGTAATCCCAGCACTTTGCAAGGCCAAGGTGGGATGATCACTGGAGGCCAG GAATTCGAGTTCAGCCTAGCCAACATGGTGAAACTGTCTCTACTAAAGTACAAAAATTAG TTGGGTGTGGTGGTGTACACCTGTAATCCCACCTACTTGGGAGGCTGAAGCACGACAATT GCTAGAACCCGGGAGGCAGAGGTGGCAGTGAGTAGATTGCACCACTGCACTCCAGCCTGG GCAAGAGAGCAAGACCATGTCTCAAAAATATAAAAAGAACAACGATCACTGAAGAAAAAA AGGTAGCACATGTGTCATAGCATATTATAATACACAGCAAAGCAGAAGGAAAAACCATCT TACATAATCTCACCCTAGTCATCTAAATTTCCTTATCTCTAACCCAGCTTTAGAATAAAA AGTAAAATAAAAATAATTTCCTTATCTCTCCACAAAATATGGTTGGTCTTCGCTATGCTA TTAGTTTCATAAATGTTCTCAAAGGGAGCGTATTTCATTGTGACCATCACTTTCTGCTTT GTAAATAATGCTGCAACTTTTTTAAGAGACAAGGTCTTGCTATTCTGCCCTGGCTGGAGT GTAATAGCTGTTCACAGGCACAATCACAACACACTACAGCCTTGGCTCAAGCATCCTGCC TCAGCTTCCCAGTGGCTGGGAATAAAGGCACACTGCAGTAAAGCTGAAACTTTATGAAAG ACACTTTGTGTATTTCTTCTTAGGACAGTTACAAATTTCCAAAAGAGTTATATCACTTTT ACTCAAAACAGCAACATATCATTCTTTTCTGGATCCTGCCAGTGTTGGGCTTGCTTTTTT TTCCTCCTAAAGCCCTGGTAACAGGCATTTGTGAGTATTTATTTATTTTTTTTAAAGACA GTTTCAATCTTGTCGCCCAGACTGGAGTACAATGGCGAAATCTCGGTTCACTGCAACCTC CGCCTCCCGGGTTTAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTAGGATTACAGGC ATGCGCCACCATGCCCAGCTAATTTTGTATTTTTAGTAGAGACGGTTTCTCCATGTTGGT CAGGCTGGTCTCAAACTCCCAACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCT GGGATTTACAGGCATGAGCCACCGCGCCCGGACTTGTGAGTAATGTATGTCTCTCATTTT ACAGTACATAAAAGCAAATTACTTTGAGTTTCCTCACCTATAAAATGGGTTAATTTAACC AGTACCTCAAGAATTATGAATATTAGGTTTGTCTGAATTCCTGATTTTTCACTAATGCAC TCATTTTGAAAAAGCTACATTTTTCTGTTTACTTATCTTCTGTTTTCCTTTTGGCATGAA TGTTAATTATATTAAACCTGTTATTTGTATGTTACACTTACTGTGTAGAAAATTCAATTG TAAAAATCAAGATTAGCTTATTAATTTTCACTCCAGTACAACTACATGAATTTTTGTTAT TCATCTTTAAAATGTTTTTATTCTTTTATCTTATGTGCATCTAACTTCTCCCTGACAAAT ATTAACTTAAAATGAATGGATTTGGAATTATTAAAAATAAGATTCAAAATATGATTAGCT AGATATTTATAACTTACACTTTGCGATCATTTAGGAGCATTCCATTCATTTTTTCAATAG CTCTTTCAGCTGCTTCCTGCGTCTCAAAGTGTACAAATCCATAGCCCTTGGAACCATTTT CATCACAAACCACCTAGGGAAAAACATATACCCATTTTTCTTTATTTGCTATTGATTTAA CATTTGTTCAGTGTTGAGAGACAATCTGTTAGCCATCTAACCTGGATATTTGTGAAATAA AGATATCCATTACTGCACAGTTCCTATTTCAAGCACTAAACTAAATGTAGCTCAACAATG TAAACATGTGTATCGGACATTTTTGGCTTACCTTACATGAAAGGATGTTACCAAAAGCAG AAAATGTATCATACAGTGCTTTATTATCAATGGATTTGTCCAGATTTTTAATGAATATGT TGCCTACTCCACTTTTGCGAAGTGATGGATCACGCTGAGACCACATGATGCGTACTGGCT TGCCCTTTATAACATCAAAATTCATGGTGTCCAAAGCACGCTCCGCTGCAGGAAGGACAT TTTCAGAGTCAATATTACTTCAAAATTTTTGCTGGCTACTTAAGATTATATAAACTATGG TGACTGGAGTGGGAGGACACATGGTCTCACAGTTGAACGCTTCCTCTTTAAGCTTCAAGA TGGCTAGACCTTTCAAGTATCACACACTAGTGTGGGACCTAAGTTGTATAAAGCAAAGAC AAATACCAGAAGCCCCCGAAATTTCTCACATATAAAAGAATTCCATATTGCTAATAATTA ATAAATTCTTGACGCAATCTCTCGCCTTAATTGCCATTAAATCTAAAGCACTTTTTTTCC TAGTTATCAAAATCCAAATTCCTTCACATACAATCTGTTTAATAAGCAGTATAAAAGACA TTACGCAACAGATTTATCTACAAGCTGGAAGTAGTTTATAGATTTAAATATTTTAACTTC TTCCCAACTACTTGCTAAAATTGGTCATTTCATTGCTAATAACTAACAATATTATATGAA AACTAGTCCATTTCCTAAAAAATGAAAGTTTCTTAATTATTGGGGGGAGGGAGGGTTTCA GTGATTCATGGCACAACTTCCATTTAAGAAAATGAAAGGCTAGACCAAGATTTGAATCAT GCTTTCAAAAGCTAATGTGAAGTTAGACATATTTGGTTTCATAATCACAGAATTTTAAAA ACACCAGGTCTGCAATATTCAGAAATCACCATTAACGCTCTCTTGACACATACAATCAAT TTCACTTTAGATCGCTGATTTTCTTAACAACTGATTTAGTTATTTCTGAATACTGCTAGA AAATTTCAAAATCTACAATTAATTTCAGGATCTATAAAGGATTGAATTATGTATACCTGT ACCATTAAAGGCTCTAAATGAAATAACACATCCTTAAATAAAAAGACTAGTCCCCGAAGA GAGGGAAAACGGTCCCTTTTAAGCCCTGAAACAATTCCTACAAATTCCATGCCAATGTAA ATTTAAAAGTTATTGACAGGATGAATTTTCCGGCCACCTCTTTTTTTATAAATGAAAGTT CCAGTTTCTAGAATATAGTGATAATCAGCTGTTAGCTCATTATCAATTGACCACACCTAC TCAGCTTCCCTAGTTTTTTTTTTTTTTTAGCTGACTTTGCTTGAGCTATTTTTCAATGAG TCACCTCTTCCTATGAAATTGAAAACTGGTCACTTTCAGAAGCTATTCTGCCTATCAATG TAGCAATAAGTTTTTAAAAAAGAACAAGAAATCCACTTAAGTAATTAATTGGATAGTAAA TTGTACATACAGAAACTAGACAAATGGAAAACTGCCATATTCTTTTCAGTAGTTAGGGTA CTGGTCTACTGGTACAGACTGATAATATATACTGTACACTGTAACCACGGCAACCTGAAG TTCAACTCTTCGAATCCCAAGAAATGTAAAAATTGTTTTTTGGATTTAAAAACGTTAAGC TGAGAAAGAGTAACACTTTCAAGTTTTCATTTTGTGGTCTCTAGAATTCATTCCCATGTT TTCTCCACCAACTCTTAGGTTGTGATAACCTGCCCCAAAGTTATCTACCCCCATCTGACA TGCATTGATACATCCTGCCTAAGGTTGACAAGAACTGTTATGAAGTGACATTTGGAGTTA CTGCTTACAGAGCAAAAGGGCAGGAAACCTGCAGTGCAGTTTTACAACTTCTGGCTCTGT GTCACTCAATATTCTGCTTCCAAAATCAGTATCAACTTTACACAGTGAAGAGCTGATCAG TAACCTAAGTTCTACTGAATGAATGTTAATAGGAGCTTAAATTCCACCCTTAAGGCCTTT TCTAATAAAAATGAATTCTTCATATTTCGATTATTTGACATGTATTCAAGTGGCCAGCCT GTAGGGGGGGAAAAAGGCAAAATTGGGCCGTAAAATGGAATTAAGCTGACTTCTCAAAGC CAATTGATCTAAAGACAAATCCTAGCAACTCAACAGACCACAGATATTATCTGTTTACAA AATTGTGTTTCTGTTAACTGTTTAGCTTCAAAATAAAAGCACAAAGTTAGCTGCATTTCC CCCATAAATTTCAAGCTCAATTTAATCTCCGTTATTTTGTACTCAGTCATTTCCCAAGAT TTACAGGTATCATGGGCCACTTTTAAAAATAAAAGAGAAACTTGAACTTCTTGCATGCTA CAGATAAGACTGGTCCAGTTGGAATTACACTAAAGTAACATTTTATAGCCAAAGTTGACT ATTTTATAAAGAAAAGCCCCTCAAAACGACAGGAACTATTTCAGAAGGTAACATAATATA CTCGAAAACCACCAGTACTGTGAATCTAAGATAAAATTTGACTAAAAATGGTCTAAGTTG CCTGAGAAAACTGGCCTTCAAAGTGGTCGGCTGCCACATCCCCTCCTCCCACTCTGCCCT TTTAATGTTAGAGAAATGCTTGATCTAGGGGAAACCCCAAATGCATGTCTCCGGTAAATT CCATTCCTAGATCCATCAGTCACTGATGAGTTCTGGGAAGTGGACTCACAAGCCTGAGGA CCACCACCACACCACACATCGCCACAGGAACTTTATCCTAAGGCCTGGTGGCTCCCCCAG GCGACTGGGCCAGGAGCAGGAGCAGAAGCAGGCCTCGGGCCTGCGAGGTTACAGGGTTCA ACACGTGGTATTTTTCGAGCACAGAACTGCACTTCCTCCCCAGGCTGGGGCGCCGGCAGG AGCTCCGGGTGGTGGGAGCGCCTCCACCTCTTACCCACGGAAGGAGCTCAGCGTTCAACG CCCCAGAATCCCGGGGCCACTGGCGGGAGCGCCGCGGAGGAACCGAATCTCACCCACCCT CCCGGCGCGTCATCACCCTAAAGTTTGAGAGCGTCTGAGGCCGAGAAAATGGTCGCAAAG GAGGAAGTAGCCGGGCGTGTGGCTGCCGGCAGCGCGGGTCCCCGCCGGCTCGGGAAACGC GGCTCCAGGGACCCCGGCGCCTTCCCGCCGGCCGTCGCGGGGTGACATGCCCTCCCGCCC CCCTCCCCGGGCCCGCCGGCCTACCCCGCCCGCCGCCGCCGCCCGAGCCTCATGGCCGCC CGCCCGCCCGGCCGACCGCGGAGCCCGGCGCTCACCGTCCGCCGGCTGCTGGAAGTTCAC ATACGCGTAGCCCAAGGAGCGGCGGGTGATCATGTCCCTGCAGACCCGGATGGAGAGGAT GGGCCCGGCCGGGCTGAACTTCTCGTAGAGCATCGCCTCGGTCACGTCGGGGTGGAGGTC CCCCACGTAGAGCGAGGCCATGGGGTAGCTGGGGGCACTGGGGTTCATCTCGGCACGGCT GCCCGCAGGGCCACAGGCCGCGACCTTTCCGTGAGAGGAGGAGAGCGAGTGCCGGGGCTG GGGGCCGGAGCCGGGGGGAGGGGAGCGGGGAGCAAGCGCAGAGGGACAAAAATCAACCGG AATTGAAAACTACTCAACGGCCGCAGAACGGGGTCGATCCACTGCCGCTGGCTGCCGGCT GCCGGCGGGGAGCGAGGGTGGCGGTGTCGGGTCCGGGCAGCGGGAAGGCCTCGGTCTCTT GGTTCCTTCTTGGAGCTGCTGCGGGGCCGCGGGCGGGCGGGTCGGTCTCGGCTGCTTCAC CGGGTTATTTTATAAAAGAGGAAGAAAAAAAATAAAAGTCTCCGGCGGGGGAGACGCGGA TTTTTTGTAAATTTTTTTGGGGTTTTTTAAAAGATTTTTTTAGATTTTTTTTGGATTTTT TAATAATAAATGTGTGTTCCGAGCCCGGAGCACACACTCCGCACTCTCAGCACTAACCGC CGGGGAGAAGGGGAAGCACCGCCTCCTGCACCCTCTACTTATACCCCGCGCCGCACTCGC CCCGCCCCCGCGCGTCTGACGCCAGGGCCCCTACGCGAGCGTCAGCGCCGGAGTAGGAGG AGACGCGGAGGCCAGGGGGAGGAGGGAAGAGAAAACAGGAGGAAAGAGCAGAGAGGAAGG GAGAGGTGGCGGCGGTGGAGGCTGCGGTGTGGGGGTGGGGCTCGGGCGAAGGGGCGGGGC TTTTGCGCAGGCGCCGCGGCCGGGGAAGCGGAGCCCGCGCTGCGTCGCGTCCGTGGGGGT GGGGAGGACGGCTCGCGGGCGGTCCTCGGGGGTGTTGGCTGAGGCGTCCCCGCCTTCCGC CCCGCCCGCCCCTGCCTCCACCAGGAGGAGCGTTAACCCGTCACCGCGGCGGTGGGCGGT GCAAAGGGCTTCCGGGTTCCTCCGCGCTAACCACCCCCCACGTGCGCGGCCGCCTGTGGC CTCTTCCCGCTGCGGCCGGCCCGGCTCCTCTAGCCCCAGCTCCGGGGGACGCCGGGCACG GGTGAGCGGGCGTGGTCCCCTCCGGGCCCGGTTTCCGAAACGTGCGTAGATGGAGCCAGC GTGGCCCCCTGCTCTCTCCTACCCGGACCGCACTACGAGTCCCAGCCGGCACCGCCGCCA CGCGCGTCGGCCGCAGAAGCGGTGCCTGCTGGGAGCTGGAGTCCCCAACGGCCGCGGCGC TCGCTGACACCAACTGGCTGCGCGGGTCCTGGCCGCCCGCTCCGGGACCCCCCAACCGTC CTGCGCGCTGGACCCCGGCACCGCTGGAGCTCCCGGCGCGGGGTTGGGGGGCAG bcftools-1.21/test/csq/ENST00000520868/ENST00000520868.fa.fai000066400000000000000000000000211467060157400215420ustar00rootroot000000000000008 37194 25 60 61 bcftools-1.21/test/csq/ENST00000520868/ENST00000520868.gff000066400000000000000000000043621467060157400211740ustar00rootroot000000000000008 ensembl_havana gene 101 37094 . - . ID=gene:ENSG00000070756;Name=PABPC1;biotype=protein_coding;description=poly(A) binding protein%2C cytoplasmic 1 [Source:HGNC Symbol%3BAcc:8554];gene_id=ENSG00000070756;logic_name=ensembl_havana_gene;version=9 8 ensembl_havana transcript 17201 21216 . - . ID=transcript:ENST00000520868;Parent=gene:ENSG00000070756;Name=PABPC1-006;biotype=protein_coding;havana_transcript=OTTHUMT00000380216;havana_version=1;transcript_id=ENST00000520868;version=1 8 havana exon 17201 17644 . - . Parent=transcript:ENST00000520868;Name=ENSE00001378950;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001378950;rank=6;version=1 8 havana three_prime_UTR 17201 17644 . - . Parent=transcript:ENST00000520868 8 havana three_prime_UTR 18565 18582 . - . Parent=transcript:ENST00000520868 8 havana exon 18565 18675 . - . Parent=transcript:ENST00000520868;Name=ENSE00002101657;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002101657;rank=5;version=1 8 havana CDS 18583 18675 . - 0 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 8 havana exon 19211 19341 . - . Parent=transcript:ENST00000520868;Name=ENSE00003465118;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003465118;rank=4;version=1 8 havana CDS 19211 19341 . - 2 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 8 havana exon 19874 19958 . - . Parent=transcript:ENST00000520868;Name=ENSE00003509544;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003509544;rank=3;version=1 8 havana CDS 19874 19958 . - 0 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 8 havana exon 20936 21090 . - . Parent=transcript:ENST00000520868;Name=ENSE00003689366;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003689366;rank=2;version=1 8 havana CDS 20936 21090 . - 2 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 8 havana exon 21172 21216 . - . Parent=transcript:ENST00000520868;Name=ENSE00002114920;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002114920;rank=1;version=1 8 havana CDS 21172 21216 . - 2 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 bcftools-1.21/test/csq/ENST00000520868/ascii-art.txt000066400000000000000000000013131467060157400212700ustar00rootroot00000000000000 21090 21171 21216 eeeee eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee GTTAGCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCACCAACACGCTGTGTTGACATGACTCGTGGAACCTGTGAAGAAGCTG GTTAG---------------------------------------------------------------------------------CAACACGCTGTGTTGACATGACTCGTGGAACCTGTGAAGAAGCTG ssssssss bcftools-1.21/test/csq/ENST00000520868/long-deletion.txt000066400000000000000000000004751467060157400221640ustar00rootroot0000000000000021090 GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC G splice_acceptor&splice_donor|PABPC1|ENST00000520868|protein_coding 21090 GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC G splice_acceptor&splice_donor|PABPC1|ENST00000520868|protein_coding bcftools-1.21/test/csq/ENST00000520868/long-deletion.vcf000066400000000000000000000011201467060157400221070ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 8 21090 . GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC G . . EXP=splice_acceptor&splice_donor|PABPC1|ENST00000520868|protein_coding;type=ENST00000520868:101719033-GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC-G bcftools-1.21/test/csq/ENST00000528237/000077500000000000000000000000001467060157400166535ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000528237/ENST00000528237.fa000066400000000000000000001661011467060157400210140ustar00rootroot00000000000000>1 1:47023070-47082535 ACCACCAAATAGGCCACACATAGAATTTCAGTTTTATTAAAATAAGCACAATGTATAAAA GCACCGTGGTGTTGTATAAACGTCTGCCTGACAAATGCAAATCTATTTTCTTTATGTAAC TCAATAGTTCCACTTATCTGAATGGCTGTACCTTCATGCACACGGGCAGCAGGCACTGCA TTGCTCAAACAGGGAAGTGAGGCTTCACCCTAGTGTGGCTTCACCTTAGGCACAGAGCAC TATCTAACTGCCCAGATCTGTGCCACCCACACAAGACCTGGGGACACAGCAGCAGACACC GATGCTGTCTCTAAGTTCATCACAGGAACAGCTTAAAATCAGAATAATAGGGAACTGCTG ATTAAAACCCAAGTGCATGGACATTCTAGAAAGAAGAGCAAGCCGTTCCACTCTCTGGGA AGTTCATGGGCTTGCAGTGGGAGTTTAAGGTATCATCTTTGCTGGAACAGCATGGTTAAA AACACCAAACTTTTTTTTTAAAAAAACGATACTACTGACTTTAGCAGCAATCACAAACAA AGGGGATGATAAACGAGGGATACATTTCAGTCACAGCAAAGAAAGATTATGTGCTTTTCC GTGCTGCAGACCGGAAGACTGATTTGATTTCCTGAATGAGGAAGGCTCCTTGCCCTTCCC TGAATTGAGGGGATGGCTTTGCTCAGCCAAGGGAGAAGACGGGCAAAGAGGACATCCGGA GGACAGAGGAAGGTGGAAGGACCGCCAGAGGAGGGTGACAGAGAAGAGAGGGAAGAGGCA CGTGTCGGCAGCCTCTGTCAACTGATGCTTCTTGCTTCTCCCTGCAGGCTGCAGCCCCAG CCGCCACAGCTACAGCGGTGAGAGCAGGCTGGATCCCAGATCTGCAGGCGGGTGAGCAGG TGGAGCCCAGTGAAGAGATGTTCCTGCTGCAGGCAATTATGCAAAGTGAGAAGTGATTGC TTTCCTTTTCAAAGACAACCCCTTTGGAAAAAGCTTTTTCCTCCAGGACCCTAGGGAAAT GGGGGTTGATGGGAACCTCAGGGCCTTCGTAGATGAAAAAGCCTGAATGGAGCCACAGAG CAGAGGCTGCTGCCTGCTCAGCAGACTTTAGCCACACAGGTTTCCAGGGGACAATGCCTG GCCAGGCCTAGGGCCTATAAGGTGTGACTGGAGCATTTCAGAGTGCTGTGGGCGGGCTCC TGTCTTCACCACGGCCTGCCTGGGCCAGGGCCCGTCTCCGGGCCAGGCGTGACTTGCAGG GAGGGGAAAGCTTCATGGAGCAGAGGCCATCAGCTAGTGCCTCTGGCTCCTCTGCTAGTT CGTTCTCTTCGTGCTGAGATAGCTGGCGGTTAAGGGCGATGGCCTCAGCTGCGAAGAGCG TCAGGTCCATTGTGCTGCTGTTCCTGCAGGGCCAGGGGAAAGCACAGAAAAGAGGGTCAG GACTCTAGGGTCAGCCAGGCCAGCTCCGGGACACTCCCACTTGCTGCTGTGGCTCTACGC TCCCACCAGATTTCCCAGAGCTGGGACGGGCTGCTCTCTCCAAAGTAGTTCTTGCCTAGG TTTGGAATCTTTCTTGACTGAGGGATTTTAATTTGAGCCCCAAGTACCATCCCTGGACTT GATGGTAGGGGCAAGCTCCCCCTTCTCCTCAGAGCACCCTCCTCTGAGCTCCCACAACTC TACATACAGGTCTACCAGAGGCAGAGACTGGGCACATGAAACACACCTGTCCCTCCCTCT CCCAGCCTGCGTGGGGAAAAAGCTCCCAGAGCAAGGCCTGCGCCGCTTATGCCACGTCCC CAGCACCTAGCTCAGGGCTAGCGTGGACAGGCACTTTGGGTTTGCAGAATAAATCTTCTA AGGCGGATCTGAGGTTTGGCATCTAAAGGCATCTGGAGGCTGCTCTAGAGAGTCAGGTAG GAACCCAAATTGGGCAATAGCAACTGGGTCACACGAATTGCGATTATGGAGGTGTATGAC TTCCTTGTGTAGCTCCTAAAAGCTGGCCATGAGGCTGGTGCCAAAAAGGTTTCCCACACT GCTTAGCCCTGGCTCTTTGGGAACAGGGCAGTCCAGCTGTAAAAGGGCTCCAGAGTCAAA CAGCCCAGGGCTGCTGTGTGGCCTTAAGCAAGTTAACTTGATTGCCACTCCTCACCTCTC TCATCTAGAACACCTCTCTTAAATTCATCGTGAAGATTATGGATATAATTATATCCAGCC CTTAGCACCACGTCTGACATGTGGTAAGGACTTACTATTTTTTTTGAGACAGATGCTTGC TCTGTTGCCCAGGATGGAGTGCAGTGGCGTGATCGCAGCTCACTGCAACCTCCGTCTGCT GGATTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCATTACAGCACCTGCCAC CATGCCTGGCCATGGTAAGGACTTAATCCTGGTGGCCACTATTATCACTGTCCGTCTAGT ACCGTACGTGCCCCTCACTTCTGCTCCTTTCATTAAATACAAGGGCAGAGGGAAGCCTTG TGTGAATAACCCATGGGTAAGGTCTGTCTTTGGGCTGTAAGTTACAGTTCAATGGGCAAA ACAGGTTTTTTTTCCTGCCAACAGTGCTAGGAGGGGCCTTAAGGTGCTGGAGGGCAGAGG ATCCAATCTAGGTGAAGGAAGGGAAGGGTGGGAGATAGATCCAGAGTAGAGGAAAAGAGA GTGAGGAGGGGAAATGGGCAGGGAGCCCCTTTGGAGAAAGCTACCTGAGCCTAGAGATGG GCTCCCCCGGCCCCCACCCCCATGGTGGCTGAGAGCTTGAGGAAGAGCATGGCGTGGGGG TGGTCAGAGCATTTACCTCTGGAGGACTTGCGGCGTGGGGAGTCCCTTTTCTGGAGCTTG CTAGAATGGGAAGGACAGATGTGTAGGTAAAGCACTGCTCCCTCCTTTCAAGAACTGCCC CACCCAAGCCAGCAGTGGGTAGGTTACTATAGGCTGCTGGCGCAGCACAGGGAAATGGCT ATGCTTGCTTGCAGGGTCAGGCCTTCCAAGCAGAGAGCAAGAAAGGTACAATCTGCAGCC GCAGCCCCCAACATAGCTGCTTCTGCATGGAGAGCCCCTCTTTCCCTTTGCCTGGCAAAG TCCTAATCATCCCCCAGGACCCAGCTCAAGGGTCACTTCCCCTGTGACGCACATTTCCCC TTCCCTGCCACCTTCCTGCCTCAGTCTCAGGCCCGGGATGGGGAGTGGGGTCTTGCTCCC TTTGTGCCCCTAGCACTTTTCAGAAGCCTTTATCATGCTGTAACTTATCCCCTTGTCTAC TTCTCTCCACTAGAGCACAGAGACAGGGACTGGGTCTCACTTGTCCCTCTGGCATGTGGC AGGTGCTCACTTATGGGTCTGGGAATGAGCCAGTTAGACACTCAAACTGGGTCCCCATCT GCAACATAGGATGGCAATGCTTGCCTCCTTCCACTGGTAGGGTCACTGAGGCTGGCCAGA GCCTGGCACACCAAGGAGACCAGAAAGTCATGGGAGCATCTGGCAGACCCCTTGGAGGGC AGAGGTCAGGTATTGTGAGTAGCCAAGGAGGATTTTTAAAAATGTTTTCTAGTGAAGACA TGAATTCTAAGCTTAGGGAAAAAATACGATCATTTGCCTTTCAGGCCAGCTGTACCCAGA CTCCCAGACCATGAGGAGAACCTATGTGCCCCAACTCGGCCACACAACAATCAGCGCAGC ACGGCCTTGCTCACTTCTGGGTGTCCTCAGCTAATGATGCTTCTATATAAGAGGAGGATG CTACAGACTTCAAATGACAATAGGATGCTTGCGGGGCTGGGTGCATGTACCAAATCCCCA GAGGACTCTGTTGGGGCTTAGTCTGTGGCCAAGTTTACAGCCAACTCTATGGCCTATAAG GGGCTCAGTCTGGGGTAACAGGAGGAGTCGATTCACTCTACACACTCAGGGATAGACGCT GTCCTCTTCAGCTGCACCAGCCACAAGGCTGGTGCTCAGCACTTGCTGGCATGACAGCTT CCTTGTGGCCATGCCACAGGCCTGAAGTGGTGGAAAACACCCCTCCCTGGAGTCACTCAC CCCCTGCACCCATGGGTGCTGCAGAACTTGGGCGGCGCTAAGTCTCTGCTTTGCATCTCG CACCAGGAGCTTGGAGATGAGGTCTTTGGCTTCACTGGAGATGTGTGCCCAGTCCTTGTC AGGAAACTCATACTTGCCTTCCTGGATGCTTTCAAACAGCTTGTTCTAGGTACAAAAGAT TCCTCCTGAGGCCACACTGCCAGGGATGGGCAGGATGTGCCTGTCATTGTTTTGATCAAC CGGCTTCAATTGATCTCAGCTGTAGCTGCAGCTCATGGCTTGGGGATGCCACAGACTGGG GCCTCTTCCCAGACTCACCCCGCACTGTCCCCTAGATGATCAAACTATATAGAATGCCCT TGGCAGGCCAGGATGGCTATGCCCTTGGTGGGCTGGATGGGTGATGAGTGGAGATCACCC ATAGAACAAAGCCCAAATTCCTTGGCTCTTCCTAGAGGACTCTCTGTGAACCTCTCAGGC CTCATCTCCCACTACCACCGACCTACTACTCCACTCTTCCTTCCTAGACACTCCAGCTAT TTCATGTGCCCACATCTATGCCCGTGCTGTTCCTTCTACTTGTGATTCTTGTCCCTCTTC CGCAGGGCAGGATGCACCCTTTAAGAGTCAGTTCAGGGCTGGGCGCGGTGGCTCACGCCT GTAATCCCAGCACTTTGGGAGGCCGAGGCGGGAGGATCACAAGGTCAGGAGATTGAGACC ATCCTGGCTAACACGATGAAACCCCGTCTCTACTGAAAATATAAAAAATTAGCCAGACGT GGTGGCCGGCGCCTGTAGTCCCAGCTACTTGGGAGGCCTAAGGCAGGAGAATCGCTTGAA CCCAGGAGGCAGAGGTTGCAGTGAGTCGAGATCGTGCCATTGCACTCCAGCCTGGGCGAC AGAGAGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAGAGTCAGTTCAGGCATG ATCTTCTAACAATCCTGCCCTGAACTCCCAGCTGGGCGGAGTGTCTGATTATCTCTATTT TACCTTGTGGCCACCGTGACAGGAGCGGGAGAGGGCACTATGAGCCCCCATCCCGATCAG GAACGCTCTCCCAGCCCAGTCCTGCTTGGCATCCCCCAACCACACTGACCCCTAGCAGGG TCTACGCAGTGCTCCCTGGGGCCGCACTCACCTGGCACACCCTGCAGACCTCGCCCCGGT CCCAGCCACAGTCGGCCCCGCAGTGACCCACGAAGGGTGGGTAGCCACTCAGCATGATGT AGAGGACCACGCCCAGGCTCCACAGGTCACAGCGCTTGTCGTAGAATGTGGCCTGGTCCG TGAAGACCTCCACTACCTCAGGGGCCATGTATTCTGCAGAGCCACACTGTGGGGGCCAGG GTTGGGGGAGGGGGAGATGGCAGAGAACAGAGAGGCTTAGTTACAGCAGAGGGGATGGCA GAGAGCAGACTGTGATGGGACTGGAGCAGGAGGCTGGAAGGATGAGATACAGATCAGGAA GGCCAGCCAGTGAGCCGCCTGATGCCACCAAGGCATCTGCAGACTGAGCTCCATCATTTT CCATCATCCAGAGGAGCAGTTCAGGTCACCTTATCCTTCCAGTTCCTCCTCCAGTAGGCA AAGACCCTTGGCCAAGAAGTTCCAGGAATCTCCCCCTGCTTCAGCTTCCTATAAACAGAT ATTTCATGTACAGGTACTTAAATGCACCAAGAATGTGGCTCTGGAAGGAGATCCAGTTCC ACACAGCAAGATTTCTTAAAGTGAATCCTGTCGTGCTCCCCTGCTAGCTCAGAGCAGGAA GTGTAACAATTAAGAGACCGTCAAAGCTACAAAGCTCTTAGAACAAATCCAACCTTCCCA CCCCTCCCATTTATAGATGGCAAGGGCAAGGCCAAGAACGGGACAGGGATCTGTTTGAGC ACATCAATGGCAGCCCTAGGACCAGAATCCAATATTCCTTTCTCTCACCCTTGTGTAGAA AGCGGCTGATAGGAATAAAACACGTTCTTTTTGCTCCACTCTTCATTATTTCAGGCTCAC CAAGAAACAACCACCTCCCGCCTCCACACACCCTGCAAAACTAATTTGACTGAAAGATGG TAAGTGTTCTCAAGAGAGGATATTTTCTTTGTTATTGTCAATTAGAATTAATGACTTTGA AAACAAGGTAGTCCAGTGTGTTAGAAGCTAAGAAAGAAACATTCCTGATAATGTTGTTTA GAATAAGATACAACACAGGCATATTAAATATGCCCTTAAAGGGCATGTCTTAAAAGGGTT ATTAGGGGCCAGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCG GGTGGTTCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTC TACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTC GGGAGGCTGAGGCAGGAGGATGGCATGAACCCAGGAGGCAGAGCTTGCAGTGAGCCGAGA TCACGCCACTGCATTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAA AAAAAAAAGGGTTATTAGGAAAATTTACTTGTGAAGCATACAAATCTCAAAAGAATCATA ATTATACTCTATTAGTTATACAAGAGATGTTTTAGGAAGAAGTAGCTCCAAGCAGCACCA TCTGGTCATGAAATGTGAAATCAGAGAAGCAAACAGGCTAACTTGGCCAAGCGATCCCAT GTGCATATAGCCTGAGACCTCACAGTTCCCACCACAGAGAGACTATCCTGTCCAGTCAGG GAGAACAGCTCTCCATCCCCCATTACAAGGGGGCTGCGCTGTGCCTTCAGCAGTGGGAAT AGGACTTACAGAACTACCCAAATGCTCATATGCAAAAGGGCTGGCCTGGGAGTAGGGTCC ATTTTCACCTGGGTCAGGAGTCAGGGCTCAGCCTGTGTTTTTTTTATTGTTTTTTTTTTT TTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGT GCTATCTCGGCTCACCGCAACCTCCACCCCTCGGGTTCAAGCGATTCTCCTGCCTCAGCC TCCCAAGTAGCTGGGATTACAGGTGCGCGCCACCATGCCTGGCTAATTTTGTATTTTCAG TACAATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCT GCCTGCCTCAACCTCCTAAAGTGCTAGGATTACAGGCATGAGCCATTGCAAACGGCCAGC CTGTGCTTATAGATATAATTTGTCTCTTCATCAGCAGAGAGGACCCAACCCAACTAACAG TCCAAGTGTCAGTTTCGTTAGCAACTAAGGGGTCAGGGGAGGCTTGAGAGCCACGAACAC AGAGCAGCAAGCAAAATGATCACTCAGGCAGCAGGAAGATAGGTCCACTTGGTTTTCCAT CCTTAACCCTCTGTTCTGGACCTCCCAGCTCTGGATCAGGGAAACACTCCAAATACTTAG GAGCCCAGAGGAAGCATACGTACTGGGGTGGTCAGCTCTGGTGTGGTTATGGGGGTACAG GAGTTGTTCAGTTTCATCCCACTGCCCAAGTCAAAGTCACAGATTTTCACTGGAGACACC TGAAAAGGAAAACAGAAGACAGGGTCACAGATATAAGAAACTACGGGGCAAGAGGAGCCA GGCATGGCTGTACGGGTGCATGGCTCCGTGGCTGTCACACCGCAGCTGGTTTTGTCAGGT CATGTTTGCTCTCCGGAGGTTAACAAGAAGTCCCCTGAGGATTTCTTCCCAAGTGTCTTA TTCCCTGAGCTCTCTTATTTCCCATCTAAGGGAAAAATGGGTGGACTATTTGGTGTCAGA TTATTGTGAACTCAGACTAAAGGAAGTATGGAACTCTTGCTGGCAAATGATGGTACAGGT TGCAGCACAGCAGCTAGGGAAGTTACTGTGTACTCCTGAGAGACAGACTTCTTGCAGCCC ATTCAGTGGAGTGTAAAGGAGCTTGCAGTAAAACCTCTGACCGCCTCAGGTGGCTTAGGG TGACCAACTTGTCTTGGGTGGCTTGCTTGGGACTTGATCAGTTTAAACACGGAAACTCCT GCGTTCCAGGAAACCCCTCAAGCCTGGGAAAACTGGGATGGTTGGTCACCGTAGGTGGCA TCAACACAGTAACCAAGTCCACCAGAACTGGATGCTGTGCCTGAGACCACAGACAGGTGC CTCATCTCTGGAGCCAACCAGGAAGGCAGTTTGGGTGCACACATGAGAATGGATGAGAAT GGCCTACATGGCATGTAAGCAGCACAGCGAGTGAACTAAATGCTGGTTCTCTGAGACCCA TGTCCTTGCCGGGAAGCCTGGGCAAGTCCCTCGACTTCTTTCTCCCCTTCCTTCCTCCCT CCCCTTTTCTCTATTTTTTCTTCTTTTCTTTTTCCTTTAGCCTCTTATTAGTGGTAAAAT ATAAAGCATAAAATATGAGATTTTAGCCATTTTTAAGTAGACAGTTTAGTGGTATTAATT AAGTACATTCACAGGGTTGTGCAACCATCACCACGATCTGTTTCTAAAACTTTTCCATCA CTCCAAACAGAAACTCTATACGCATTAAGCAATAACTCCCATTCTTTCTTCCCCTAGCCC TGGGTAACTTCCAATCTGACTTTATTAATTAAGACTTTCTGTCTTTATTAATTTGCCCAT TCCAGATATTTCATATAAGTAGATTTACACAATATTTGTCCTGTTATGTTTGGCTTATTT CACTTAGCATAATGTTTTCAAGGTTCATTCATGTTGCAGCATGTATCAAAACCTCATTCC ATTTTATGGCTGACTAGTATTCCATTGAATGTATGTACCACATTTTGTTTATCTGTTCAG CTGCTGATGACCACTTGAGTTGTCTCTACCTTTTTGGCTGTTGTGAACAATGCTGTAATG AATACTGCTATACAAGTATCTGTTTTCAATTGTTTTGGGTAATACCTAGGAGTGGAATTG CTGGGTCATATGGTAATTCTGTGTTTAGCCTTTGAGGAACCGCCAAACTTTTCCACAGAA GCTGCACCATTATATAATCTCACCAGCAATGTATGAGGGTTACGATTTCTCCATAACCGT AACAACACTTACTATTTTCCATTTTTTAAATTACAGCCTACCTAGTAGTATGTGGTGGTA TCTCATTGTGGTTTTGACTTGCATTTCCCTAATGACTAAGGATGTTGAGCATCTTTTCAT GTACTTGTTGGACATTTGTGTACCTTATTTGGAGAAATGTCTGTTCAAGTCCCGTGTCCA TTTTTAAATTGGTTTGTCTTTTTGTTGTAGAGTTTTAGGAATCCTTTATATATTTTGGAT ATTAAACCTTGACCAGATATATGATCTGCAAATATTTTCTCACATTCTGTAGATTGTCTT TTCACTTTCTTGATAGATAATGTCCTTTGAAACTTAACCTCTCTTTTTCTTAAGAGACAG GGGTCTCACTATATCACCCAGGCTGGCCTCAAACTCCAGGCTCAAGCAATTCTCCTACCT CAGCCTCCTGAGTAGCTGGGACTACAGGCATGCAACCGCTGTGACCAGCTAATTTTTAAA TTTTTTGTGGAGATGGGGTCTCGCTTTGTTGCCCAGGCTGTTCTTAAGCTCCTGGCCTCA AGGGATCCTCCTGCCTCAGCCTCCCGAAGTGTTGGGATTATAGGCGTGAGCCACTGCCTG GTCCCAATTATTCCTCTCTTTCGCCTTGCCTTTCCTCACGTTCTTGTTATGAGACAGAAT CTCTGCTGCCCAGGCTGGAGTGCAGTGGTGCAATCATGGCTCACTGGCTATACATGTTTC CTAACTTGAGTTTCAGTTTCCTCGTCCATAAAATGAAGGTAATAATAGTATCTACCTCAT GATATTTCATAAACACTAAATAAATATAAGTGCCTGGCACAATGTAAGCACTCAAGAAGT GTTCACTGTAATTATTAGTAGTAATCATCATAATAATGATAAATTATAAAGGTCTACGAC AGAATCAGTGACAGAAGTCACAAGATCTTATTTGAGCGAATCCATTATTATTCCCCATAA AAGAGTTGTGAGTAGCAGACTGACTCATTCATTCAAGGCCACCCCTTATTTATGAGCCGC GGCTTCATCCAGACCACAATATATATGCTCTTGAATACACACATGTATATACACGCAGAG CTGTGAACGTGGGCCCCAACACCACCAGTGCCTAAATCTCTCCTAATAAACACAGAATTT GTCAAATTCATACACTTCCGTTTACTTAAAGAGATCTGCTTCACATAAGATTAAGTTGTT TGGCTGGGCATGGTGGCTCACGTTTGCAATCCCAGTACTTTGGAAAGCCAAGGCAGGTGG ACTGCTTGAGCTCAGGAGTTCGAGACCAGCCTGGCTAACATGGTGAAACCCCTGTCTCTA CTAAAAATACAAAAATTAGCCAGGTGTGGTGGCACATGCCTGTTGTCTCAGCTACTTGGG GGGCTGAGGTGGGAGAACCACTTGAGCCTGGGAAGTCGAGGCTGCAGTGAGCTGTGATCA TGCCACTGCATTCCAGCTTGGGTGGCAAAGTGAGACCCCGTCTCAAAAAAAAAAAAAAAG TATTTACGACTTCCATCAACTGATATAAAGATAGATGCATTGGACTAGAAAATATTAATT TTGTGCAGGTCTCATATATTTTCCAAACTCTCAGGCTTACATCAATCACACTGATGATCA AGAGCGAAGAAAGGACGAGGATGGGCAGAAACATCACACAGTAAGTGTAACATTCTCACA TGTCCAAGACGATCAGTTCAAGTTGGTGTCTGAGGCCAACGGAACTGCTAACAATCCATC CTGAAAGCAAGGGTGGCTTCCTCGGTAAGTATAAACTATAACATTCCAAATCAGGCCCAA AGTACCTTTTCTGGAGATTCACACAATATATTTTCTGGTTTCAGATCACGATGAGCAATG CCTGACATGACAAAGAGCAAAAAAATGGTTAACATATGCAGATAATTATCAAACATTCCA CACACAATTAATTTTTTCCAAATGCTGTAGTTCGCAGATTAATTCCCAATTATGGTACAT TAAAAAATCAACGAGCTGCAGGAGGCAGAAGTAACCAGCGACACAAACCAAAAGCACAGT TGATTCTGCGGGTTCTTTTGAAGAGGAGGCTTTAGAAGTCTGGCAGGGATAAGAAGGGCT AAATGAATCCCAGCCAGCCTACCCCTCAGTACCACAGTGACCACCAAGAAGAAGGCCTAA TGCAGAGCAGAGCAGAGAGCTCTGCAAACGGCAATGCTTGGAACAGCAATGCAGAAATAA TTAGTGCCTTGTTTAAGAGCATCTCAGGGGGCTTAACTGCTCTACCTCATTTCTTCTTGT GTGGCCGATTTAAAAAAAAAAATTCCTTCAGTGCGACTGTCTGAATGTTCAGAGGAGCAA GTGTTAGTTACCAAATCTCCCAAAGTGACCTATTCCCTTCTCACCTGCTTTGCATGTCTA AGGCAGCCCTGCCAGCAGCAGAGCAAAGACCGCTTTGGCACCAGGATGCTGTTATTTTTG TTTTTTAAAATAGAGATGGAGTCTCGCTATAGCCAGGCTGTTCTTGAAATCCTGGCCTTA AGCAATCCTCCTCCCTTGGCCTCCCTAAGCATGGGGATTACAGGTGTGAGCCACCTCGCT AGGCCCACTGAGGGTTGCTGTTTTTAAGAGAAAACCTCTGCACTTTGGCCAGGCCTCCTG AAGGCGACTGGAGATAGCAGCTTAGCCCATGAGGGGTTAACCTGCTGACCTGGCCAAGAA GGCACCTCGGGGAGAGCCCTCTTCTAACCAAAGAAAGGGACAAAGAACTAACTCTGGGTC ATGGTGTTTTGGTGGAGGACACAGAAACCTCCCTTTTGTCTTTCCTTCCACAGCACATGC AGCACAGAGACAGGGCTGGAAGGCTGAGCAAGAGTCAGAGCTACAGTTGGAAGTATTGGA AAGCGGCAGCGGATTCTCGGGGTGATGGGAAAAGCAAAATCTGCTTCACTAAAACTCCGT CGGTGATCAACTTTTTCAGCAGTCCTCCGATTCCCGACTAGAAGGCAAAAGCCTGGCCCA GGCCACGGGAGGCACTTCACTAAAGAAGAAAAACCTGAGCTCCAGCAAGCTCAGTAACTT CATCAGTCACCTAATTGAACGAGAACCCAGAGCAACTCAGTCCAGGCTGCACAAATTGAG TAGCACTGCTCTGCAGCTCGCTGCACTAAAAGTGGAAGATATTTTCCATTACAGCAAGTG CTCCCACAGAAGGATCACGAGCCACACACGGAGCCTTACTCTCCAAATAGGCGCCCATGG CCCAGTCGTCCCTTAGCCTAAGAACTCAGAGAGCCAGGCTGTAATAATGGGGCTGCCGTG TGAGCACAGCAGCCATCGAGCTGCTCCGGTTCATTTCCCAGAGGTTGAGCTGCAGTGTGT CCAGTATTTAAAAGTATGGAACTTGTTTCAGGGCTGACCCATTCTTGCCCAATTCATCTT CCCCGTGTGAAGTTATTTAGCAAACAGCCAAGTTCAGCTGGAAATCGTTTTTCATCCCCT CCAACTTCTAGTCACATGGGCAGCTGGCCAGCTACATGTTAACAAGCGCCTCAGAACTCC TAAGACACCACCGGCCTCTGTTCCCTTCAGTGCATTCTTGTAAATAAATAAATAATAAAA CCTGCCTTTACCACCCCCTCCAAGGTGTGGATCTTGTAAAAAGCGTGACCCAGTTTTGCA ATCTACAGAGGCAGCTTGGGGAGCAGTTGTAAATCTTTGTCAGGCAGGTGTTACCTCTAT GCATCCCAGCTTTCAGAAACAGAGCTGATGCTATTCATCATGCTGCGGAAGGTACAGACA CCCCCTTCTAGTTTTCATCCTAGGTGCAAGTCAGGGCCCCAACATGGGCACTGTCAGTAT GCAGACCTCTTTCAGCCACTGGAGGAGGGAGGTGGGGTCAATGAACCTGAACCTCCTGGA CATGCGCCACACTGGTCTGCACCGGATTGTGGGCACCAGGTGGGATGTGTGAGTGGCATG CCTACCACTGGTCCCGGGCACCCACAACCAACATGGCTGGCCAACATCCGCAACAGCAGA GGGGGCAGACCTAAGTCACAAGTTATTCATTTCACTCCCACCCCCAACAGGCAGAATGCT TTAAGGGAATTAATATTAGGAATAAAAATGCTTTCTTCCTGGTGGGAGGTGAGGATGGAG GAAATCGTTATTTATTGAAGAACTATGACATACCAGGAACTATGCTCCATCTATGCTGCA CATATACAATACAAACACAAGATACACATTTTTCATCTATAAAAAGCTTAGAATAGTGCC TAGCACATACCAAGTGCTATATAGTGTTAACTACAGTCGATGATGTTATTATCTCAAATT CTCACCATAGGGTAGGCATTATTACTGAGAGAACACATAGCTAGAAGAAAAGTGAAACCA GAATTCATTTTTTCCAGGGTACTGCTGTTAGGCAAATTTAAAAAAAAGTATGTAATAGTC AAACAGATTTATGGAAATGTAAAAACAATTTGTGGAAAGATTTAATTCACTACAAAAGTT CCTGAATAATCAGTCATAGGAAAGGGGCTGTAACCTGAAGCGTAAATCAAATACTAGTAA CCTGTGAGTTACCAATGTGCTTTTCAACAGATACCTCAAATGTACATGTTAATAGAAAAG TATAAGCTGGGCACAGTGACTCACACCTGTAATCCCAGCACTTTGGGAGGTTGAGGCAGG AGGATCGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACAGAGGGAGACCCCATCTC TACAAAAAAATACAAAAATTTCCAGGTGGTGGCACACACCTGTAGTCCCAGCTACTTGGG AGGCTGAGGTGGGAGGATCACTGGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCCTGATG GCGCCATAGCACTCCAGCCTAGGTGACAGAGAGAGACTTTGTCTAAAAAGGAAAAAAAAG GAAAAAGAAAAATAGATTTTTCATTTACTGTGAACAAGATATATTAAACTACATATATCC TATCATGCCAATTTTGAAAAGAGACAGAGGTGATGTATATTTTAAGACTAGAAGGAATAA CATCAAGATATTCACACTAAGAAGGTTGTATTGTGTATGAGCTTTATATTCCTCACACGA TAAGAATCTAAGAAAAGAAACATCATCCACACACAGTCACACATACCCTGTTCAATGTGA AATTTATTCTTTCTCCTCCCTGCTCTTTCTCCTGTATCCCTGTGCTGCTCAACAGCTTCA CCACCCACCCACCATCCGCAGCATAAGCCTAGGAGCCATCCTGGACTGTTTCTCCCTCAA CTCCCATGGGTGAGCATGTTCACACCTCAAGCTGCCTTCCAGCCACACCATCTCCTGCAC CAGCCCTCTGCCTGGCCTACCACCTCCCTTGGTACCCAGAGGCTGGCCAGCCCAACCCAC CCACCAAGGCAAAGGCTGGGTTCACCTTTGGTATGCAGGAAGTCAAGGGCAGCAGCAACG TCCCGCACCACTCGGCTGGCTTCTCGCTCATTGAAGTGCTTTTGCTTCTGGATGTGGGCT AAGATGGAACCTGGGGAGCAGAGGGGACATAGAAGAATGCCTTTTTGGGCTCTAGTAAGT ATAAGTTTTTTTTTTAGACGAAGTCTCACTCTGTTACCCAGGCTGGAGAGTAGTGGCACG ATCTCGGCTCACTGCAACCTCCGCCTCCGGGTTCAAGCGATTCTCCTGTCTCAGCCTCCT GAGTAGCTGGGATTACAGGCAGGCACCACCATGTCCAGCTAATTTTTGTACTTTTTTTTT TTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCAAGTGA TCCGCCTGCCTCAGCCTCCCAAACTGTTGGGATTACAGGCGTGAGCCACTGCGCCTGGCC GTATAACTTCTTAGAGGCCAAGTTTTCCCAAGTTTGGAAAACTTGGGGTGGGGACATAGG GATTCATCGCTGACTCATCACTACCTGTCCAGCTCCAAGTGTGGGGCCTGGTACGGAGGA GGTACCAGCTTGTATGTCTGTTAAACAAAACTGGACTACTCTCTTCTGTACCTGTCTATG AGGAGCTCAGAAGCGAGAGAGAACAACTATAAATAGGGCCAAAAAACACTAATGATGCTG AGGCTGATTTGGCTTCTGCAATCAAAAGGAATAAAACTGAAGGCACTTGGAGCTGAGGGG GCCTTTCTGCAGCAACGTTTTCTCCCCTGCATCTGATCTCTGATCCAAACAAGAGCACAA ACTTTCAAATGGAAATGCCACACCCTTGCCAGACATGTAAAGGCCTGGGAAAAGGGGGGA AAAATGGGTTTTCCGCCTGAGCTTTCCCATTCATTATTGTTTTGTTGGCAATGGCTAACA TTTACTGAGTAGTTACTAGTGCCATGTGCTATGGAATACTCTTGAAATAAACTGTCTTAT TCTCACCACAATTGGACAAAATGGGTAGTACACTTATTCTCGTTTTACAGAGGGAGATCC TGAAGCCAAAAAGAAAAATGGTTGAGCAACTTGCCCAAGATTACGCACCAGTAAGGGGTG AGGCCAGGACTTAGGCCCAGGGCGTCAGTCAGGCCTCCGAGTCTGTGCAGACATCCCCCA GCAGGACTTGTGGTCTGACTGCTGCAGGGATGGACTCTCTTGAGCCAACCACACTGGGTC TGGCCTCAATAAGCTACATTAAGTTTACTGATATGGCGACAGAGGATCCCATCTGCATGT AGCATTTCAAACATGTAATTAACAGTCAGTCATGTGTTATTGGGTGGTGCAGGGGCAGAC ACAGGCAGGAACATGTGGCTTGGCTTCATGTGGTTTATGTTTACTACTAGAAGCCAGCAT TTCTGGGCTGAAGGTATTATCTCTCTGTCCTAAAAATGGCACATGTCTACTGTTTTTTAG GGGGGATGGGGAGGGCATGAGAGAAGGGGAAGAACTGCCAAAGATTGTTCGCTTGCCAGA TTAAACAACGGATCCCAATGTGCTAGGGAACATTCCCAGAAAACCGGCTCATGACTAGGT CCTAGCTTGCTCTGCTGTAGTGAGCCTCGTTTCCAAATCTGTTAAAAGGAAAAGCAGAGA ATAATGCTTTACATACTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCCCA GGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCG ATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGTGCCAGCACACCCAGC TAATTTTTGTATTTTTAGTAGAGCCGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACT CCTGACCTCAAGTGATCTGCCCACCTTGGCATCCCAAAGTGCTGGGATTATAGGCGTGAG CCACTGTACCTGGTCTACTCTACATACTTCTAAGACATCCCCCAGCATACCAAATTGTTT TAATAATATTAGCAGCCAACATTTATTGGGCCCTTAGTGCCTACCAGACACTGTCCTAAG CATTTCACATGAATTATCTCATTTAATCTTCACAGCAACCCAGTGAGGTAGGTGCTATCA ATATCTCTATTTTATAGAAGGGAATATTGTTTAGAAAAGGTTAAGTGACTTGCCCAAGAT CACATGGCTAGTAAGTGATGCAGCTAGACATAACATAAGCTTTAGCTGTGTTGGTTTCTA AAGCACGCTCCCTCAACCACCAAGCCCCTCCGTGTGGCCCTCCATGCAGTTCCAGACATC CCTGCAAGTGTGTCCTAAGATTGGGGGAGTGATGGGAAGGGAAAGGGTTTCTCTACCCCA CCTCATTATGTCAGAAAAGCAACTTAAGTATACACCCCAGTGATTATGTGTGTGGGTGAT GGCATCTTTCCATCTGAAGGATGGCACATTCTCAGGCTTCCCCTTTATCCTGGGTCTGTG TCCCAAACAATAGGACCCTCCTCTCCTCTGTTTTAGCCTTTCTAGACTTCGCAATGTATT TGAGAGCTTCCACCCCATAATTAATGTAGTTAAACAGTGAACATGTCAAAACGGGATTGA TAAATCGATGACTAAATGTATCTATATATGACTCCTATTATAATGAAAAGGCATTTATAA AATACCCACACAGGTGACATTCTAAGCTCTGCAAAATGCTAATTATCATCCTTCCCTCCG GCCTCCCTTCTCCCAAATCAAGGGCAGTTTTTAAGTCCTTCATCCTTTTTATTAGCTTGA CTCGTTTTGGAAGTCTCTGGGATTCATGATGGATGATCACCACCCTGGGTCTTAATCAGA AGTCCACACACATACTCAACGGTAAGTACCTCCTTGCAATTTCTCAAAGACCAAGTAAAA CCTTGTGTCATCTTCAAAGAACTCAATCAGCTCCAAAATGTTCCTTAAATAGGGAAAATA GGAGGAGAGGGAAAAGGGGGGAAATGGTATTATATATTAAAGTCTACTTACAAATATACA ATGAAAAAAATATACAACACCTGGTAGTGGGGCAGAAACCAACTTGAAATCAGAATGCTT ATTAAAGACCCGCGTATGGAAGCAGCCAATGGTGTTAGCAAGATTCAGGTCACCTTATCT TTCCATAATGTTTAGTCTCTGGTGTTTTCACCAAGTCTGTGCTGTCAAACCCCAGCCCTA AAACCCACTAGGTAGAGTTATAAAAAAGTCCCGGTCACATTAAACTGAATAAAATCTGCA GCCGACTGGAAGCAATTGCGGCTAATAACACTGAATACTAGGTGTGTGTCCTGGAGGCAA GCAGCAAATAATTACTTGCCCTCCCTCTTGCCCATAAATCACGGGGCAGTATTTACATTG CCTGGAGAAAATGGAAACATCTGTCAAATGGACTTGGGGCCTAACATGGGCACCGCTAGA CCCTAACTGCTAAGCGCTGCTTAATGAAACGGCCGCGTTCCTGGCCACTGTAGCACTTGT GGCCTTCCCCGGTGAGCACTCTCTGTCTGCCCGAGTATTTCAGTGCTCTGCCAACAAGGT CGTCTTGTAACTCAGTAGGGAAGCCACCAGCCTGGATATTGGAGGTGTTGTGGGCTTTTT TTCTTTTACAAAATAAAATAAACCAAGTAGAGTCTCTAATGCTGAACTAAGAAGCTGCAG GGCTGAAAATAAAAATCTGTCCCTCATAAAAAAAATGCTGACTACTTTGGGAGATATGAG GCTTTTACTAGTGTGAAGGCATCCAAATAAGATGGGCAAAATGGCCTAATTTGAAAGAAG ATTGTGGAGGCAGTGCCTGGAGTTAAATCAACAGCAGCCCCCGTCCTCCAATCCTCCAAG CTTAATGACAAAGCCATCAATACCAGGCCACTGGCTCCCTGCTGACCCTACCGTGGAGGG AGAGAGGGGGAAGTGGAGTCTTAGAGGTGCCCCTGATTTAAAGCCACAGTGGGAGAGCTG CTCATTTGGAGCTGGTGGTGGGCAGAATGAACTGGGGCTAGAGATGAGCCGGACCCAGCT ATCTGGAAGGTTCCAGGATCTTAGTGGTATCTGCACATATGTAAACATTCTAGGAGCAGA AACAGCAGCAAATATTCTTAACAGTTCTCCTCATCTTGGTATTAAGGCAAGTCCTTAAAG ATTTCTACCAGGCAACACTCAGTCAACCTAGTTTCCACAGGTACCGAAAGAAATAAAACC CCATTTCCCCCCAACAACCACTGATTCAGATAGTTCATTCTTCTAACTTGCTTGAATTGA TGATATTTACAGTATTTCAGAAGAGATAATAGCTCCTTTGCTGTTACTGCTGCTTTTCCT TTCTCTCCCTAACACTGAAAGGGGCGGAAGGAGGTACCTGCCTTGTGGGGACAGGAGTGA GAGCTAAATGCTGGAGTCAGGAGATGGTAAGAAATAGCCTCCTCTTCTGTGGCCAAGCGT CCCCCCAGAGAAGCAGCGAGAATCACATGATACTCACTTGTTTCCCTGACACTGATACAG CGTCTCCACCTCTCGAAACACCCTACTCCGACTGTGCCCTGCTTGTTTCTCGATGATCTG TGGGAAGAATAAAATCTGTCATGTACACCCACCTGACTTCCAAACAGCCCTTTGGCAGGA GTCCTCTGGGAGAATGCAAGGCCACACTCAGTCCAAATCCAGTGTCCAGCAGAAGTCTGG CCTAGGCCTTGGTGACACCGGCACTGTGGCTCTGTTGGCAAAGCAGCAGACTGGCCTCAG GGCTTTCCAGCTCAGCTGAGCCCATTCCACTCTGGCCAAGCACAACACCAAGGAAGTGAA TGAGGCTGCTGCCCCCAGCTGCCCAGGGGAGACTGAGGCAGCCGGCAAGACAAAGAGCTA CCTTACTCAGCTCCACCTCCTGTGGACACCTCTTTCTGCCTTAAGGGTAAGCATTTACTG CATCTACTGAAGGATCTTCTCATGCTGGAGGGAGAGGCTGATGCAGGACACCGTGGCGAG GAGCTAAAGCTTTGACACCCAGCTCAGAGGCTGCCTCCACGATCCCCCTGGCAGAAGTAG GCTCTTCCTCTTCTGAGAACTTACTCTCTGGCAGATACTGTGTTAAATGATTTATTTACG GCCGGGTGTGGTGACTCACACCTGTAATCCCAGCACTTCTGGAGGCTGAGGTGGGTGGAT CACCTGAGGTCAGGAGTTCTAGACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTG AAAATACAAAAAAATTAGCCAGGCGTGGTAGTGGGTGCTTGTAATCCCAGCTACTCAGGA GGCTGAGGCAGGATAGTCACTTGAACTGGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGT GCCATTGCACTCCAGCCTAAGTAACAGAGAGACTCCATCTCAAAAAATAAATAAATAAAT AAATAAATAAACAATAATAATTTATTTACATAATCTCAGTTGACCTTTATGACAACATCA AAAGATAGGGAGGTATGAAACATTTGCCTGCAGTCCAGAGCTGACTCCTAAGCCCTTGCT ATCCCATACCTGCTTAGATGCTCTAACTTCTTCGAGGACCTGGAGGCTTTGTCTCTCCTG TGATACGGTGGGCTGCTCCCCCTCCACACTTTTACCTGAGATGCTTGTCAAATGCTGACT GAAGGAACAGATAAGCCAACAGATGGGAGGGTGGTTTCCAAAGGGACTGGCTGCCTCTGC AAAGCTCTCTGGACCCATCTGGAGCCTCAAACCACTGCACACCGAGCCTGTGAGCAAATC TGCAGAGCCTAGCTCTGCCTTACAGCTCCAACGTGCACAGTGGGCAGCACAATGACATCC TCTTCCTTCATTGAGACTTCAAACTTCTCCGATATGATGTGGCACAGACATCTGTGACCA ACTGCAATTTTCTAAATAAGTGTGTCTGTTTGTAAACCACAGTGGGCCCATTATCTGAAT GGAGAGGTGTAGTGCTGGGGAACAGAAGTGATTCAACTTCATTCCCCAAGCATTTCAGAT CAAAGTCATGAAGAACTTTCTAGCAGGCAAGCCTTCCACAGCACAGTCTTCTCTGAGGAA GTAATGGGCTCTTGCTACTAGAGATGGGGGAGCAGAACATGGACAACTATCTGGGGAGTC AGAGGAAATTCAGGGTTATCTTGAAATTCCATCCCAACCTTGAGAGTCTAGGATCAGCTG GGTGCCTATAGGAAAAGCTGTAATAAGCTAAGTATTGTGGGGCCATGTTGGGAGAAGTAG CCCATCTCTAGGGAGCTTTGAAAGAGTAGGGGAGAGAAGAAACATGGGCAGAACTGCTGA AACCAAGGAATTGCCAAGCCAGAGTCCAGTGTTTGCCTCAAAGATGCCAGGGGGGATGTG GAGGAAGGGCCAGGTTTTCCTCCCATTATCCAACCTTGAAGAAATATACCTCTCATCCAT AAATGTATTGAAACCTTTGAAAATCAGTTTATGTTTGTGGTTTTTACCGCATTTAGACAG ATATATCAATTTTTTTTTTTTTTTTTTGAGACAGAGTCTCCCTCTGTTGTCCAGGGTGGA GTGCAGTGGCACCATCCTGGCTCATTGCAACCTTTGCCTCCTGGGCTCAAGTGATCCTCC CACTTCAGCCTCCCAGGTAGCTGGAATTAGACGCACATGCCACCACACCAGGCTAACATT TTTTTTTTCTTTTTGTGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTG ATCTCGGCTCACTGTGCAACCTCTACCTCCCGGGTTCATGGGATTCTCCTGCCTCAGCCT CCCAGGTAGCTGGGATTACAGGAATGCACCACACCCGGCTAATATTTTTGTATTTTTAGT AGAGATGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAATTCCTGACCTCAGGTGATCAG CCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACATGCCTGGCCTAATT TTTCTATTTACACTTAGGCGTATGTTTTAAAAATCACTTGTAATTTATACTGAGCTGTTT CCCAAAAGAAATTAAGACAGTGCTCTTGTTACCATGTGAAGCAATACTCCAGCTGAAAGG AACGTGGCTTAGCAGACTTGCTCAACCTTCTAACCCGCAGCTGGGACTGTGGAAAGTTGG TTCAAAGAAGAGAAAACATTTCCTTCAGGAGCCCACTGGGCTGGGATTGCCAATGTGAGG TGGCATTTGACCTGGTGGCTCAGGTGGGTGATTTGAAATCAGCTTGGATTTAAAAAGACC CTTTCTCTAGGTCAGTTAGTCCTCAAACTTTGGTGGCTATGAGACTCAAGTGGGGAATCT GGTCAAGCCACAGAGATCCAGACCCTATCCTACATCTGGAAACCTGGATCTGTGTGTGCT TTGTTAGAGCTCTAAGGGCTTCTAACACATAGTAGCATTCACAACTGCCCTTCCTACAAC AGTAGTCCTCAAGGATTAGTGAGTGTCAGAGTCACCAGGAGAGTTTGTTAACATTTGTAT TGCTGGGCCCACCCCTGTTTCTGAGTTGGTACTTCTCAGGTAGGGCCAGGTAGCTTCTAT TTCTAACAAGTTCCCAAGCGATGCTGAGGCTGGTCCAGGGCACACATTTTGAGAACCACT GCTCAAGATCCAGCTCTTCTTCCATGTGGAGAGGGCAAGTGGAGGCACAGAGGGGTGACA TGAGCCACTCCAAGGCCTTACAGCTAATTAAAGGCAGCAATGAGGCCAGAAGCCACTTCT CCTGCCCCAAAACTGAGTGCTCAGTCGCTTTAGTTTTGTTTTCTTCTTTTAATTTTTTTT TTCTGAGACATCATTCAGATGTTACCAAATCAGTCACCTTAGTTTTTAATCCTCACTATC ATGCTAACATCTAACACTTGGATAGCATTTTGTGACGTGTAAAGTGTTTCCACCTCTCCC AGGATATTTTAATTTTCATCTTCATAACTGCCTCAGGAGACTGAAGGGCAGGTATCATCA TTTAGAGATGTAGGAACTGAGGCTTACGGACATTTGATGACTTGCCCAAAGTCAAACAGT TATAGTTTGTCAAAATAGATATTCAGGTAGGCCTTCTAATTCCAAATCTGGTTGTCCACT CCCTGAAGCTGACTTCATTTGTCAGAATAATGAGAAACTTACTATGAGCCAGGCATTGTG CTAAGCACTTTACCTATATTAACTTATTTAATCCTCACAACAATTCTACATAGGTTCTAG TATTATACCCATTTTACAGATGAGAAAACTGAAGGACAGAGAAGTTAAGTAACTTGCCCG AGGTACACAGTAAGTAGAGAAACCAAGATTTGAATCCAGTGAATACAGCTTCAGAGTCCC CATTCTTATGGAATATAACATTTATTTGGTTCAAGATGAGCTAGGAATGACTATTTGCAA AGTAAAGCCTGGCATTCAGCTGAGACACTCACTTTGACGGCATACTCTTTGCCATTCTGT AGGCTCACGGCACCTTGAACTTTGGCATAGGCTCCCTCTCCAAGCAATTCAGAGGTCAGC TTGTACATATCTAGAGGTGAAATGGATGAGAGGAATAACAAGATGAGTCACCCTACTGCA AGCTCAGATGGGAAGAACTTTTGTGGCTCAGCTTCCCTGATCAGACGACACAGGCACCCA ATGACTCTAGCACTCAGTGACAAGGAAGACAAGTAGCTTTCCCAGCCACCTGAGGACCCA GTTTCTCAACAACAAGACCACATACAAGGCATCCTGTTCCTCATTTTAGCGATGAGGTTA GCAAAAGGGTCTCAATTCGGCACATACTTCCTGAATATCTACTATGTGCCAGACAGCATA ACAGAGTAAGGAATAAAATAAAGGCCAGGTGCAGGGGCTTACACCTGTAATCCTAGCACT TTGGGAGGCCAAGCCAGGAGGATTGCTTGAGGCCAGGAGTTCAGAACCAATCTGGCCAAC ATAGCAAGACCCCATCTCTAAAATATATATACGCATGATCCCTCTCCTCTAAGGGTCGCA GTCCAGTGGGGAAGACAGACACATACACAGGTGACCCCAGAATAAACCAGGCATTGGTAA ATACTATCACAGAGGGACAAAGTACAGTTAAAAAAAAAAGTTGGGGGAAGAAAGGGTTAA ATCTGTTCAGAGAGGCTGGGCATGGTGGCTCACACCTGTAGTCCCGGCACTTTGGGAGGC CGAGGTGGGCAGATCAAGAGGTGAAGAAATCGAGACCATCCTGGCCAATGTGGGAAACCC CGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACGCGCCTAAAGTCCCAGC TATTTCGGGGGCTGAGGCAGGAGAATCGCTTGAACCCGAGAGGCGGAGGTTGTAGTGAGC CAAGATCGTGCCACTGCACTCCAGCCTGGTGACAGAGTGAGACCCCATATCAAAAAAAAA AAAAAAAAAAAAAAAAAAAAATTGGTCAGAGAATCTGGAGGATCATCAGAGGAGAAGTGG TATGATTTGAATGAATATTCATTTACTCATTTACTGAGCACCTATTATGTGCCAAGTTCT GTGTAAGCACTGGCTATACAAAGGAGAATAAAACACTGTTCTATTTTATACCCCATACAT GGAAGTCATTGGAGGCTTCTGAGAAGTCTCCAGAAGTCACCCACAGGAAATAGAAGTAGG ATGCAAAGGACACCTTGAGGTTTTTAGGGTACTGAGTCATAGTTGTTCTAACAGAGTAAT AGACCTGGGTTAAAGGAACATCTAGATGACCTGCCCAAGCTCACAAAGAGCACAGCTCTT TGAGCCCCTTCCAAAGGAGGCTACATCTCCATCACAGCACTAGCTGCCTGACCTCATCCC CACTCGGCCTCCATTCTTCAGCCTTTTCCTCTTGAGGCACCTAGCATTGAAACCCACAGC CTGAGCAGAAGACATTTCAACCATGAATTAGATTTTATCACTCTCAGTCAGGAGAAGTCC TGTCATTGCACAAGCTGTCCTTAAAAATAGGAAGTACTCTCTTGTGTTAACTGAAAGAGC AAAAGAGCTGTTGATTAGGAAACTATTTGAATACCTTGGGATCTTTGTCTCTCCCCCATC CCCATACCCTGACACACACAGACACACACACACAGACACACACCCCTGCTGTTTGAGTTA AAGGCAAACAAAAAACCCCTGCTGAAAGTACCTTCTTGGTTCCATCACGGTTTGGTCTTT CAGTTGTTTATAAGAGCAGATGGCACACTGTTATTCGTAAGTGTTTTAAATGACATGCTT CTCACAATGGACACATTGGCATTAGCCCTTTACACATATCAGGATAGGTGGGTGGCTGGA GGTCCCATATTCCCAACCGATAAAGTGCTTGTTATTGGAACCACTTTACAGAACAGCCAA TTCACTAGTGTGTCTGGAAGGCTGGAAGGAGGGACCAAGAGGCGAAGCTACTTCAGACCT CACAACGAAAGAAAACAAAACAGATGAAGTGGGGCACGTTACTCCTAGGAGTAGCTACTG ATCCTCTTGGTGCTTTGCACAAGTGTCCAATCACCCCATCACATGCCCAGTGATAACAGG ACCCACACTGAGCCTAGTGCCTCGCACACAGAGAGTGTCAAAAAATGTCTGATGACCCAA CATCGTTTCTACTGAACACAACACGTATTCTTTAAAATGTAGTCAAACACACACAGCATA AGTAGCTACAATCTGAGAGACAAATTCTCTGCTTACAGGAGACTGAAGTTTCATTTGCGG CCATGGCCTTTGGTGTTTCTCTCTTCCTCTTATATAGTTCTATCTCTCAGCAGCCCCTCC AGGAATAGCTGAGGGAAGAATCACATCTGAAAAAAGGAAGACCCCAGGCAATGCCACTGA TAGATGGGTCTTCCTGCTCCCTGAAAAGGAAGCAGTACCTGAGCCATTCACAGGAGGCCA GTGCATCATCTGAGAGCTTTTTCCATCCCTGCTCTCTTTCTGTAATGCCCTGTGTAAACT CCCTCATCCCCATCTTATCTCCCTACCACACAGATAACCACCATCTGGCTCTAACTTGAC GCATTCTGTGATCGGACCTGTGGCTCCCGGGATGCTCCTCCCATGCTTGGGAAGCTGCAG GCCCAGATATAGGGAAGTTGTGTGACCAACCTTCAAACTTTCCTGGCAAGGAGTCAGTGG CCCGGCCCCTCCGCTTCTTCTTCCTCCTCCTGTCACCATCTGCGATGGGAAGGGGTTCGC TACTGCCCATCTCTAGGAGATAAGAGGAGATGTAAGGGAAACATCACTGTACTGATCAAG CTGTAAATTTACCCAGAAGGAAAAAAAAAAGGTAGTGGGGGAGGACCCAGGAGGTTTACA CTGATGGTTTTTAAATATCTGTGAAGACTATTGATTTGTTTTGACCTAGGAGGAAAAACT AAAGGCAAAGCCATTATGGGAGATCATTAACTGTGGAAAGGAGCTCAGACAGGCAGGCTA GATTAAAAGAGGCCAGCGGAAGCCTGCTTTAACCAAGCTCATTAGCGCGTGGATTTAGAT CTGCCACTGGTCAAACCATATTCCCCAAACAGAACAATGACTCCATAGGCAGAACCCCAC CTGTGACATCCTCCAGCCTCAGCATCAGAAAGGCAAAACCGAGAGAGCTAGGCAAGAAGG GGGTTGGGAGTGGGGGACCATGCAGATGAGTCATAGGCTCAGCAACATCGCTATGGATGC ACACAGGGCACAAATGGCCTGGAGTGGAGACAGCCTCTGTGAAGGTAGCAATAGGGCTGG GGTTCAAAATAGCCCCAAATTACTTCATGTCCAAGAGCACGGACTTGAGTGCCTATGGAG CCTACGGCATCCTCTCCTCCCATAGCTCCTCCATCGGAAGGGCTGCAGGTAGTGCCCATT CAGAAGTCGGCAGTTGACAGGTCTGTGCCAGGCTGCTGGATGAGGTCACTTATTGCAAAA AACCTTATTATCTTTCATTGGCAAGCACCTGGCTCCCAATCTTAAAAGGAGGATTTGTGA GGCAGGCATTCAGACACTGCACAGATTGGGCAGAAAAAGTCCGGATGGAAAGAATAAGCA GGACACTGAGATAGGAAAGAGAAAAGGAGGAACAGTGAACCAGTGCCCAATCACAGTCCT GTTTCTAAGACACTCTAGTATGGGCCTTTCCCTGTTAAAGATAAATTACTTATAGAACAT GTCATGCCCCTGATCCAGAGTGGAGCTTTAATACTCTTTGCCTGCAGTTAGAAATAATAA GATTTCTCCGAAGTCTCTGGGTCTAAATCCCCACCAGCGTGATTAAACCTTTACATCCTT CTAAAATAGAGGCACTCGAGTGCTGATGGGGCATACGATGTGAGAGACTTTTAGACCAAC CTTCAATAAACACAGGCTCTTGGTTGTTGGTGTTTTTTTTTTTTTTTCTTTCTTTTTTTT CTGAGAGCTTTTAAAATGGAAGCTGGTTCTTTGCCCATTGAGGGGAAAGGCCCACTCTCT TCTCAGAGGATCTGGCGGCATACGACCAGAGAAAGAGCAAGTCTGCTAGGAAGACTGATT AGTGCTCATGCAGGTCCATACACTGTTCTCAGACGCAAGTACGTGACAGCCATCCGGAGA GAGCACACAGGATGGCACTTTCAACACCACAATCCAGAAAGCATGGTTACGCAGCCAAGT GCCTGACAGCTCAATTTAGGCGCATTCTTCCATCCATTTTGGGGATCTGATGACAGCACA TTTTAAATTATAGTTTAGAATGGGGAACAGATAAACACACAGATAAAAGAAATCCACAGA GCATCTCAAAATATAACTCTAGCCAAGAGCTTCAAACACAAGATATATCTGGGGACTGCA ACACCCTATGAATTGAAAGAATTAAACATCTGGCTAGGCACCATGGCTCACGCCTGTAAT CCCAGCGCTTTGGGATGCCGAGGTAGGCAGATCACTTGAGGTCAGAAGTTCGAGACCATC GTGGCCAACATGGTGAAACCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGG CGGGTGCCTGTAGTGCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGG AGGCAGAGGTTGCAGTGAGCCGAGATCACGCCATTGCACTCCAGCCTGGGTGACAGAGCA AGATTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAATCAGCACCTCAACACCCACCCTCACCAAGGTAAATTAAAAGGAAAAAAGCTGCC CAAATGTATAACATGGTGAGAAATTCAGCAGAAATAAAACACAGGGTCACTCATCTTCAG GAGCTCAGGGAGGGGGTGCTGGCCATCGGGGCAGCAGGCTGAGAAGGAGGAACCATTGTC TCTCTCTCTTGCGCTGACCTTGAATGCAGTCCAGTGGCAACCCGTGTCTGCATCTATTTT CTCATCGGCACCGCAGGCCCAGTGCAGAGGAAACAGATTTGGGTTTCAGCTCTTTCTCCT TCCCCTGTCCACACTTTGATGGAGGGCCCCAGGACAAGCAAAACAGCCAAAAGACAGGCA GAGCAGAGGAGCAGCAAGAGGGCTGGAGGCATTATAATTCACAGGGGACACTCAGGCACA CGACTCTAATGAGAAAACCCTGTTAGCGACAATTTATACTTGGTCTTTACCACAGCAGGG CTGAGGGAGCCGCTTGCACGAGAAGCATACCTCACAGCACCACCGCACACGTAACATTAG ATTTTATGGCTTCACACACACACAAAGACAGAGTACCTGGTATATTCTGCATGGATTTCA ATGAAAGAGGGTACGCCAGAAGGGACAAATGGTTAAGACTTTCCTTGGAAATGGAACTTG GAGAGTTGTTTCTGAAACTAGGAAGGAAAAAATGTAGGAAGATGGGTGAAGTGAAAGAAA CATGCTTAGCTTCCCTGGTTACACAGGGGGAAGCGAGAGGTGTCATAATCTCACCAAGGG GTCGCTAGTTGCCCATGTGGAGCCTGGCCACACACTATTTTCATCACAGAGTCCACTAGC AGGTCTGTGGGGCCTTAATTCATCATGCAAACACTCATGGGATAAATGCTGCCTCAGGGA GTGGGACCCCCGCAGTAAAGCTGCACCTTGGCTCACCTGCTTCCCTTGGCCTAGGAATTC TTCTTGGTCATCAAAAGCCGGCTCGATAGTCCCAACCCTTTTGCAGCTCCCTGATAACTC CAGATGAGTTAAGGTTTCTACAGAGACTCTGGAAGTCAGTTAGGTGCTATGCAAATGGAG GGTGTTACTGAGCAGAACTAGTAGTTGGTGCTCCATCCTCTGCTCCCAAACACCCTGCGA GAAGCTCCACGAGGGCACTGATTTTATTTGGCCTTGAGTGCTCCCCTGTGTTCCTAAAGG CTGAGATTGTCCCCTGTTCACTTGTTTCTCCTACAGATCATGGCACAGTGTCAGACACAT AGCAGCCATCAGAAATTGCACTGAAATAGAAATGATATGAAATGACATGCATACTGTTAG GTGTGGGGTATGTCACACTGGCCTTTTAGGTACCCAGTGCACATCCTGAAAGAAACATGG GTACAACTTTGCCCTGTAGACAATGCAGAGTAAGGCTACTTAGTTTTATGAATCCAGTTC AGGAATTCTACTAATTCCTGGATAAACTCCCTTTCGAAAAAGGGTCTAGGACACAAAACG TCCTTCACTTTCTTATCTTTTCTTTTCTTTTTGAGATGGAGTCTTGCTCTGTCACCCAAG CTGGAATGCAGTGGAGTGCAGCTCAGTACAACCTCTGCCTCCCGGGTTCAAGCGATTCTC CTGCCTCAGCCTCCAGAGTAGCTGGGACTACAGGCACATGCCACCATGTCCGGCTAATTT TTTGTACTTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCT GACCTCAGGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACGTGAACCA CTGCGCCCAGCCAGGTCCTTCACTTTCTAAACAGAAGCCTGGTTCTTGCTATAGGATTGG GCAATGTGTCTGTTATTACAGAGGAAGAAGTGAGCACTTCTTTTCAGTTTCAGGCAGATC CCAGCTGGTCTGGAGGCTCCCAGCACTTCCGCTGCCTCCAGCCCTTGCCTTCCTCTTGGG AACGGCTCGGCGGTCCACCACATGTGTCTATTAGTGGAGGTGGAAGTGGAACTGAAGAAG CAGCATGCTGCTTGCTGACAGGGAAGGCACACAGGCTTGGCATCAGGCGAGCAAGGCAGA AGCCCTGGTTCAGATATTATAACAGAACCAAGGCCAAGTTACTGTGCCTCTTAGAGTCTC AGTTTCCTCATCTATCAAATAGGTTTAAAAACACACCCGCCCTGTCTACCTCACAGGTTG TTGTAAAGACCCAATGATGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGG GAGGCCGAGGCAGGCAGATCACCTGAGGTTGGGAGTTTGAGACCAGCCTGACCAACATGG AGAAACCTCGTCTCTACTAAAAGTACAAAATTAGCCAGGCATGGTGGTGCATGCCTGTAA TCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCCGGAGGCGGAGGTTGC GGTGAACTGAGATCGCACCATTGCACTCCAGCCTGCGCAACAAGAGTGAAACTCCGTCTC AAAAAAAAAACAAAAAATACCCAATGATATACTTCACATAAATATGTTTCCAAAAACATA TGCATATGCACAGGTATGTATGCCCATATATGAACCCAACAGAGTAGAAAGACTAGACAG AAATACGTAAAACTGCTAATACGCTACAATTTTAAAAAGTGCCAACTACATGGATATTCT GTACATATTATCTCTAATTCTTATCATAATCTCAAAAGGTAAATATTTTTGCCATATTTC AGGTAAGGAAAGAAGCTCAGAGCAGGCAGCCAGTAGATTAAATAACCTACCCAATGCCAA ACATCTAGTTAGTGGTTTAACTGGGATTCAAACTCAATGCTGCTCTTTCAAGTCCAGACC ATTTCTAATCCATAAGAGTTTTCTCTATGTGATGGGGTGATTTTTATTTTCTTTTTTATA TTTTCAGTATTCTCTAAATTGTACACAATGAAATTTATTTTTCCTGCTATTATTGTTTAA CTCACGTTTTATTTTTAAATAAAGTACACCATAATCTTTCTCTAATACACATTGGAATTT GGTATCTGATTTTAGTTTTTAAAAATGTTTCTAGATTTCTCTGTATTAAAATTCAACATT CAGTGATGAAAGAAACATTTTAGGAATATTGGTGCCATGAAGATACTAATTTCGCAATCA TTCAAAACAACCAATGTTATTTTTATTTTTTAAAAAATGCTACTTCTTGGCCGGGCGTGG TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAG GAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAAA TTAGCCGGGCGAGGTGGCGGGCGCCTGTAGTCCCAGCTATTCGGGAGGCTGAGGCAGGAG AATGGCGTAAACCCCGGGGGGCGGAGCCTGCAGTGAGCCGAGATCGCGCCACTGCACTCC AGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAATGCTACTTCTTAA AAGTAAATATTTTATAAAAACAAATGAAAAAATGTGCTGAACATTGGAGCCTGAGAGCTA TGGCTCTCCTCCACTGCACGAACTGCAGCAAGCTGCTTAGCTTCTCTGAGGATCAGTTTC CTTGTATATGAAATGAGGTAAGCAGAAGGCCTGGGCTGCCCATGCCACAAGGCTGCTGTG AGGATCAAATAAGAGACTAGAAGTGAAAGCACCACTGACTTACTCTTCAATAATGCTATA TTTATTGGGCACCTACTGATCGTCTGGTGCTAGACAGTGAGAGTATAAGAGAAGACACAG TCTCTTCCCTGATGGCGTTTAAATCTGCTGCTGACGCTTAAAACAATTTCAACATAGTAG GACAAGTGCTGGGACAGGGAGGTACCAGGTGCTGTGGAGCAGGAGAGAGGAAGCTAACCC AGTTGGGTAACTAGAGGAAGACACAGCTAAGCCTCAATACCTGAGGGATGAGTGGGACAG GGCTGAGGCCTGGAAGAGAGTGTCCCAGACCAAGGAAGGGCACAGGCTGAGGCCTGGAGG AGGGACACAGGGCCGGTGGGGGCCACTGGTGATCACTCAGGCTGGCAGGGGCACAGAGCA CATGGGAGGAGGGATGACATTAGCTCACAAGCAGTCTCATCGTCATCGATGATAATAAAT GTCTCCATTCCTAGGCATACGTTTATCTTGTTTTCTCCATTAAAATAGGAATGCATGTTT CGTCTCTTTGTAAAACCTGTGAGTGAACGAGCACTGATGGTACTGAAGGTATAGTAAGTG TGAAGGATACAGATCCAGGAATCATCCTGGTTCCTGCAGGGGAGATTTACAGAGAACTCA TAGAGCAGATGAGGAAGGGTTATGGAGGCTCCCTAGAAGGACTACTGCAGCACAGAGATT CCTGACATGCAAGCATCCATCCACCATTCTGCTCCAGAAAGTGACCTCGAGGCCCACCCT CTGGAAGAACTGTGTTACTTCTCCATAGTCTTATGAGCCACATTGTCCCCAAAGGAACCA GATCTGTACTCCAAATTTTGAAGAGCCTGCAGAGAACTCATCAGCTTTCATATCTGTGCA TGAAACCAGAGATGATCCTCTCCCCACTGAGAACCCGACTTTGCTGGCTAGCTCAGCTCT GCAAACTTAGCTCACACTCCTCTCCCAACCACTTCAGAATTCTTTTCAAGGTCTCCCCAA CCTTTAAGAGCGATTTCCCTCAGCCACAAGAGCTTTCTTGAGAAGAAATAGTGGTGAGAG CAAGCAGAGAAGTGTAATTACCAACCCAGCTGCCTTCTCGGGCATCAGCTAGCTGAGCAT TCCAAAACAAATGGAGAACGGAGAAAATGATCAGGAACTGAGGGACTGAAAGGAAGTGTC ATGGGCACTCTTAAGGAAGTGGCCAAGACTAAGAAATGTGACAGAGGAGGCAATGAGGGG GTACCTGGGGAGACTGACCCCAGAACATTTACATCTTTGAAGTAGTAGCCGGAGCAGTAT TAGAGTCCACATGACTACTCCTAGTAGTGACATTACTCACACACACACATGCTGCTTACT GTAGGCCAGGCAGCATTCTAAGCACTTTACCAACGCTACACTTTACATATACTAACTTAT TTAATCATCACTACTTTATGAGCTAAGTATCCAGATTTTACAGATGAAGAAACTGAAGTA CAAAGAGATTAAATGATTTGCTCAAGGTCGCATAGCTTGTAAGTGGCAGAGCTGAGATCT ACATCTAGATGGTCTGGCTCAGAATTCAAGCTTTTAACCATTACACTGTATTTAAACCTT AATGCTGAAAGGCAGAAGGGGTAGCTAGTAAAAGTAGCCAGGCACCAATGAGAATGCTTT TGTTTATAAACCTTAGCACAGAGCTTCCCTGCTGATGTGCTGTGAATGAGGTATTGATCC CCTCATCAGGCCTCCAGTCACTCACTGTTACTTAGGTGTGCAGAACAGTATCATTTTCAG CGTGTGCTATGATGTGAAAAGGTTGGGCAGCACTGCCCTAGCTTCTGGAAATATGAAGGC ATTATTACCACATTATCATCGTCCTATTAATCAAAAACTTCATTTATCAGAAGTTTCTTC TTCTTGCTCTGAGCTTGCCTTGTATTTTGTGTTTTGTCATCTTATGAAAGATGAGCTACC AACCAAAGTCCACCTACATTATTTCATGGCAGTTCTGGTGTCAGGGACAGGCTACGTTCT TCTGTCTGACCCATTAGTGGGAAGATTTGGTTTTGTGGCATCATGATTATGCTGGGACAA GGAAAGGGTACACTCAAACAGACACTAGTCAGATTTAACACATGATGGATGAAAGGAGCC ACTTGTAAAGTCAGCTCAATCAAAGGACCGTCTGTCCATAGCGATACTGCAAGGGGCTAA GGTATTCTTTCCCCAAGAGTCTGGTGTGAGGGGAGGCTGGGCTGCAGCATGCAGGTGGCA GCATTTCACTCCGCTGCAATGAAACTGGCAGGTGAGGCCTGCTAGGGTGCCAGCAAAGGA TCCCCCACAGGCCTCAGACAGGACTGGGGGCCTGAGAGTCCTAGAGACAAAAGGTCACAA CTCCAGTCCATCTTCTACCTCTGTTCTGATTCTGGGATCACAGGCAGCCTTCAGAGCTGT CACTGCATCTCCTGGTGGAAGGAACAAGAGGAAGGACATGGAAGGGGAGAATGAAGTGTG TGCTGAAGAAAGAGCAAGCAGGAGGAAAGGGCTGGATGGGAGTGGGGAGCAGCGTGTAGA AAGCTGACAAAGGTGGGCTGCGCTCAAGGCCCCCAAGCACAAACGCAGCCCACGAGGCTC TCCAACCCCAAGCCCCTGTCTACCTTCCAGCCTCAGCACCCAACACAGCCATTGTTTCAT GTAAAAATGAAACTAGTGGCTAGTTTCACTTGCCATTCAAGGGATCCCACATGTGCTTTT CCTTGCTTTTCCTTGAGTCAGGTGCTATACTTTGGTTTGCCGCAGAAGTACTTTATGAGC ATTTCTATTTTGTTACACAGAATATTAAAGAGATCCGTACTCAGGGTTGGAATTCAATAA AACTGACAATTTTTGCTACTTCATCAAAGACATTCTTGTGTGAAAATGGCATTAAAAAAA AGCTGGGTGTGATGGCTCATGCCTGTAATCCCAGCACTTTGCGAGGCTGAGGTGGGCAGA CCACCTGAGTTCAGGAGTTCGAGCCCAGCCTGGCCAACATGGCAAAACTCTGTCTCTATT AAAAATACAAAAATTAGCTGGTTGTGGTGGCAGGTGTCTCTAATCTCAGTTACTCAGGAG ACTGAAGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGGTCATG CTGTTGTAGTCCAGCCTGGGTGACAAAGTGAGACTCTATCTCAAAATAAAAACAAAAACA AAAACCTGGGAGTACATAGCAGTGGAGAATATAGTGGCTACTGGCACAGTTCAGCATCAC CACCTTGACCAAGGCACCAACAGTCTTACTCATTGTTGCTTTCCAGCAACAGACAGCATC TTAGTACGATTACAAAAATCATTTTAACTGTGCAGATTCCTAAAGGAGTTTTGGGGACCC CCATGGTCTGCAGTGTATGCTGCGAACCACTGGCCTAGGTGATGGGGAGGGACTGGGTGT GACTGGAGCTGTGCCTGGGGGCCACGGAACTGACTGTGATGTGAAGAACAAACTGGAGGC TAGAGCAAGAGGGCTGAAAGAGGCTGCTGGAACAGCCCGGGGCAGGGTGAGAAAGGCCTA CAACAGAGACAGGGAGAGCAGGGAGAGCAAGGAAGAGGAGGTGAGGTGTGTAACAGAGTG AGGGAATGAAGTCATCGAGGCAGAACTGGTTCTAGTCCTACCAAATGACTGAAGAAGGTG GGGGCAAAGACCACAGCCCTCCTTGAAGGAAGGGACAGTGTTTAATTCCTCTGTATCCCC ACTGCCTAGCATGCAGCCAGGAAGAGGAGGGCCTCATATACTTATGATTACATGTTTATT AACCAAAGTCAGGTCACCATAACAACAGTAGGACCATCAAACAGGGGGAAAATTCAGGAA GTGGAGCTGGCTGGGGACGGGGAGCAGGGAAAGACAATGGCACCACCGGGGACCTTCAGA TGAAGAAGGGTGACACACAGCCACCAGGGACTATGAAAACTCACCGATCAGGCTAAAACC ACTCTCACTCAGCCCTCATCTGACCCAAATCTGCAAATGAGGCATTATTCATAATCTCCC AGGCATGACAAAACCTCTGGTGACAGTGTAACACAGAACACTTCAAAATGTCATCATATA TATCATATATACGTTAAAAAAAACCTGAAAAGACACATCTCAAATTATTATTATGTTTTG AGCTACGGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGC AGCCTCCGCCTCCCGGGTTCAAGCAATCCTCTTGCCTCAGCCTCCCAAGTAGCTGGCACT ACAGGCGTGTACCACCATGCTTGGCCAGTTTTTAAATTCTTTGTAGAGACAGTCTTGCTA TGTTGCCCAGGCTGGCCAAATTATTAGCAATGGTTATTTGGGGAGGGACAGTGTCTAATT CCTCTCTATCCCCGCTGCCTAGTATGGAGCCAGGCAAAGAGGGGCTTCATATACTTCTGC TGTATTTTATCTTGTTTTGTTATGAAGTAGTTGTTTTAATTTCATAATTAAATAGATCTG GCCAGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCCAAGGCAGGCAGAT CACTTGAGGTCAGGAGTTTGAGGCCAGCCTGGCTAACATGATGAAACCCGTCTCTACTAA AAACAAAAATTAGCTGGGTGTGGTGGTGCACGCCTGTAATCCCAGCTACTCAGGAAGCTG AGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCCGTGAGCGGAGATTGCACCAC TGCACTCCAGCCTGGGCGACAGAGGGAGACTCTATCTGAAAAAAAAAAAAAAAAAAAAGT AAATAAATATGTTTTAGTTACATGTTTTCCTTATGACCCTTCCATGTCATTCTGTAGAAA TGTGTTCCTCCTACTAAGCGTTATCTGAGTCGTACCAGGGCAGCTCCGCTATTCCTAGCT AACTAACTAAGTGCTGAAAACCACGGTCTCTTACCCGCCCTTTCCTCTGGATGTATCAGA TCATTTCAATTTGAAGTAATCTAAAAGGATAACTAAAATGTACACCCAATCTTACCTATA GGTTTTTCCAACTTTTGAGAAGATACCATCTGTAAACTTGAAATCCCAAATGAAATAAAG CTCCTGTCAGGAAGTTGGTGTCTTCCAGCTACACGAAGTGTCTCAATGGCCTTTGTGCGT AGGTGGCAATCTTCAGTTCTCCATTGGCCTCTGACATGGAAACCTTGAAAAAGCAGAAAT AGAAAGGAAATCAAAATGCTGACTTCTTTAAAAGGACCAGAAAAGAGAAAGATCAATCTG AACGTGCCCCAAACCTATGAGTTACCCCACTAAGTAGATATACACGCAGCAATCACAGGT TTCCCATCTTTAAAATCAGACATTTGAATTAAATTTTTTGTAGAGATAGAGTCTTGTTAT GTTGCCCAGGCTGGCCAAATTATTAGCAATGATTATTTGGGAAGGGGTGGCTTCTAATTC CTCTCTATCCCCACTGCCATTAAGCACTGGAAGATTTAACAAAGGTCTGAGTGAAATTTT TCAGATTCTGTTTCCATTATGGGATTCCAGACCCAAAAAGATGTAACTGGACCTGGATGA TAGAGATAAGACACCTCTGCTCTGAGGAGTCTCAGGCAAAAGATAAAAGTTGACAGGCCA GGTGTGGTGGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCTGAGGCAGGTGGATTGAC TGAGCTCAGAAGTTCAAGACCAGCCTGGGCAACATGGTGAAACCCATCCCTACAAAAATA CTAAAATTAGCCAGGCATGGTGGCACACACCTGTAGCTGCTTGGGAGGCTGAGGTGGGAG GATTGCTTGAGCCCAGGAGGTCGAGGCTGCAATGACCCAAGATCATGCCACTGCACTCCA ACCTGGGTGACAGAGCGAGGCACTCCTCTGCTATCCACGTTTTTAGAGAAATGAGCTGGG CTCTCTCTCTTAGTGGCCAAGTCCAAGTCTCACAGGCAAGAGGAAACAGAGCCCGAAAGA TAAAGTAGATGCTGAGAGCAGGAGGTGGCATGAATGGGAACAAGGTTTTGTGTCGAATAC ATAATTATTGCTAGTTTTCAATCTGATGACTTCATTTTCTCTATGTTCACTGTTATTTTA ATACCATGGCTCTAGCTATACAAGTCAAAGTTGCTTTGTCAACTTCCCTATGAAATAAAT ATGCATTTCCCCTTTTCTCGGTGGAAAAGCCCTGAAAATGCAGTTTAACTCTGAATTCTG AGCCAAAATTTCTAAAAAGGCTTTCTAACTGGAAGTTGGGTGTGTTTCACCATGACCTCA AACCACATGCCCCAAGTGGGACTTGTGCCCAACCCCCACCCACTGCCTCCTTCCTCTGAC TTCTCTTCTTCCCTATCAGATCACGTCATCCTGCCAGTTATTCCTCAAAGGCAAGCACTT ACCTTTTTCATCTTTGCATTACCAGCATCTAACATAGTATCTGGCAAAAATGGGCTCTAG TGAATCTGAATGAATTACTTAATACACGAAATATCTCTTTAACATCCAATAAAGATGTTA GCACATTGGACAGTCCTTCCTACTATGCTCTTTATTCCCAAACAAATCTGAAACCCAGTA AAACTGTTTCCAGGGCCTAAGGAAACTCAGGGTATGCTCTCTTTCTTCACTTCTACTACC ACACTTCCAGGGACAGCCTTGAACACCATCCAACGACAGGATCTGGCTCCATTAGCCAGG CTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAGCCTCCACCTGCCAGGCTCAAGTGAT CCTCCCACCTCAGCCTCCCAAGTAGCTGAAACTACAGGCACGAGCCACCACGCCTAATTT TTGTATTTTTTGTAGACACAGGGTCTCACCATGTTGCCCAGGCTGGTATTGAGCTCCTGA GCTCACGTGATTTGCCTGTCTCAGCCTCCCAAAGTGCTGGGATTATGGGCGTGAGCCACC ACGCCTGGCCTTGAGCTTCCATTCTGTCTTTAGTCTTGTCATAGGTTTAGACCCCCACCT GGTCCCTTCTTGTTACCTATGGTAGGAGTTGGCAATTTTTTTTCTGTAAAGTGCCAGATG GTAAATATTTTAAGCTTTGTGTGTCACATGATCTTTGTTATGACTCAATTTTGCATTTGT AGAGAGAAAGCAGTAGACAATATGTAAATCAATGATTGTAGCTATATGTCAATAAAACTT TATTTTTGGACACTGAAATTTAAATTTCATAGATTTTCATGTGTCATAAAATATTGATCT TTTCTTGATTTCTCCCCAACCACATAAAAATGTAAAAAGTACATTAGTTTGCATCCACAC TAAAACAGGCAGTGAGTCAAATATGGCCTGTGGGCCATACTTTGCCAACCCTTGGCCTAC AGTAGAAAAAAAACCCCTCAGAATTCCTTATGGGCTTTGTGTTATTTTGCCACGTGGAGC CACCTTAGGCTGGGGAAGTAGAAAGCACAGGGCTTTTGGGCATTAGGTCCTAGGTTCCAG TTCTGGCCCTACCATCTACCAGCCGGGTAGCCTTGGACATAAAATTCAAACTCTCTGAGC TTTACTACCATCATCTATAAAATGGGGCAATAACACCTAGATCACAGAGTTGTCATGGCA ATTAAGTGAGCTAATGTATATAGAGCTCGTGGCACCAGTATCTGGCATACAGTAGGCACT CAATAGTAACTCTTATTCCAGCTTCTGACATGGCTTCTCCAGATCAACTGCAGCTCTGGA AAGCAACCCAGCCAATCTGTGAACCACAGTTGGCCGCAGGAGGGAATAAACTGACAGCAA ATACAAAGGCAGAGAGAGAATGTGGAGGTTTTCAGATACATGTCACAGGATTCTAAGTGC CTGGTTAGCCCTAATTCCTTCTGGCACCATTTAAAATTCCTCTGGTCCCTTTTTCCTCCT CAAAAATTACTTCTGACTCTCACAGTTCTTAAAGATTCTTAGCATTCTTTACCAACTACC CAGATGGACCCTGGAGCCCTCTCCTCATTCCTGTACCTCCTGCTGGTATAGGGCTGGGGT GGGGAAGGGTGACCATGGCCAGACCAAACCTACACAGATCCATCGGCCTGCAGCTGGGTC TTAAGTAGGCTGGGCCTGGCGAGGCACCCAATTCTCTCTCAATTGTTCATGAATTTCTTG CTGTACTGGGAATTAAATTTCTTCAGTGCTTAAGAACTAGACCTTCTACAGACGTTTTAG AGCAAAAAAAAAAAAAAAAATCACCATGTATACAAACAAAAGATCCATCACATTACTTTC AAGACAGAAAACATCAGTGAGGCACAGGTAAGGCTAAGGTTTATGGCATCTCTACCCTTG GTCCAAAAAGCCAGATCTCGACCTGTTACTTCCTTGCTCTAAAACTTCTAATGGGTGTCC ACTGCCTCTGGAGTAACCAAGCTTCTGTGCTGTCACTCACGGCCTCCATCAACTTGTCCC AGACCAACCCTCTATGGGAGTCTTAACCTGCAGTCTCGTCAAAAGGGACTGTATTTCCAC CTGATTGCTCTAACCAATTCCCAGCTTCCTACACTTGTGCATAATTAAATTACCTGTAAC ATTTTATTACGCATCTTCCCCTAGACTGTTAGCCAGGGACAGGGTAGAGACTATGTCTCC TTCATCTCTGGGACCCCTACACCTAGCAGAGGCTCTGGTATGGGGCAACCACTTCATAAT TGTTAATGAATGGATGGAAACAGCTGAAGTTATTCTTCCCTTAAGCTGTTTTAGCTGGAC TCTTATTAGAAGACCGAGTACAGTCTGGGTCACTGCCACAAAGCAGAAAAACCGAAGAGA AAGAAAAGAGGCATGACCAATGTGATCCAAGCAATGGAAAACAGGTTTTAAGAGTGAGGT TAAAGAGACCAAGGCTGTTTAGCCGGGAGAAGAGAAGATGAGGTTTAACTGGATTCTGGC TTTAAGTACAGAAAAGGTTCTCATGAGAAAATCTTGATCTCATCCTCCCTTTAAAATCAG AAGAAACTTTTCCATATTCATGGAAAATGGAACAAGAAGAAATGGCTTAAGTTAAGGCCT GAAGGGTTTAAGCTGGACAGAAAGAAGAACCAAATTAGGCACCACTTTTCCAGAGATACT GTTATTGTACTTTTGGCAAGTGAATTGGAGGAGTCTTGCTTGGCACTCTTGTTGAAGGCT GTGAAAAAAGTAATATATGTGCTGCTCTGTTCCTGTTTACTGTGGAGAGAGGTGAAAACA CAAGTCAGGTAAGATTTTCTAACGAGCCACTGATTTTTATTGACCCATTTCCTACAGGCA CTTTCTGCCATGTTATGCATTGCAACCATGTGCTGGAACAATCTAGTATCTCAAAGGTTC CTGACAGGGCAATGGAAAGAAAGAGAAGGTAACAATGCGGGGGAAGGGAAAATGGCCCTA ATAAATATACTTTCTATAAAAACAGTACCAAACTGGGCATTCATATATTTATTAATATTA TTACTATTAAAGCTCACATTCATTGAGCACCTACTGTGTGCCAGGCACTGTGCTGTTGTA TCTCAATTCTCATAACAACCCCATGAGGTAAGTAATATTTGTATTCTCATTTTACAGATG AAGGAACAGAAACTCAGGAAGATTAAATAACTTGCCCAAGTCACACAGGTAGCAAGTGAC AGAGCCAGGACTCAAACCCAGATAGCCTGACTCTAGAGTCCACATACCTAACTACTGTCT CTCTGTAAGGATGAGAGGCTGGAATATAAACTCTAGTCTCTCTGAATCCTGTTTATATTC TCAGTTCTTCCTCATACAGTCCCAAGCCAGGACATTAGCAAGAGTTGAGGCCTCAGAAGT GAACCAAAATACTCCTCTGATTATCAGCATCTATAAAATGGGGGCAATTACACCCACATC ACAGAGTTGTCATGAGAATTAAGTGAGCTAATGTATATGGAGCTCATGGCATCAGTGCCT GGCATACAGTAGGCACCCAATAACTAGTAACTGTTATTCCCGCTTCTGATATGGCTTCCC CAGATCAGCTGTGGCTCTGGAAAGCAACCCAACGACTCTGTGAACCATAACTGGCTGCAG GAGGGAATAATCTGACAGCAAATACAAAGGAAAGAAACAGACTGAGGACTCTCAGATGAT AATGAGCAGGTGCAGGACTTGAATGCCAGCCTCTGCACTCCAAGTTAGTGCTCTGTCCTA CTTACAGACTCTTGTTGAATTTGAGGGTGAGAAAATGAAGAGACAGGATGTGCCAAACAG GCTGCCTCCCCCGACAGACCCTTTTGTAACGTCAATCTCCCATCAGAACCCATGCCTGAA ATACCAGGGTCCTGCAGCTTCTGTAAACTGGTTCTAAGATTCTACTAGCTAAGGATGGCA ATGCACTGATTTATGGCACTGTGGGTGCTGCCAAAATGATCACCTATTAAACCTATCAAG CAGACCTAGTCCATGCAGCTTCCAAACTAGGCCAGTGATTCACCGTTTAAGCCTCTTCAC TGATGTCCCCATTCTGGGACCATCTTTGCTCCAGTCTAACCTCCGTCCTGCTGCCAGAGA AAACCGAGCGCCAGTCAGGGCATTTGGAGCCTCTAGCATAAGGAAGATAACATGGGCCTT TGAACTCAGCACTGCTAGTTTTGAACCAAGCTGTGCCCTTACTATCTATCTAACCTTGGG GAAGTCACTTTAATCTTTCTGAGGTCTGGTTTCCTCATCTTTAGATTGGAGATAAATAGG CCTATATTACAGGATTAAATATAGTATGTAAAGCAACCAGCATACTGCAAGCCACAAAGC AAAGGAGACACTTTATAAATGCTAGTGTTCTGCTCCCTACTCCACTCTCTACATTTTAGC CAAAATCTGCCAATTCGGCTTACTTCTTCTCCTCACCAACTCCTCTCCCCTCCCACAACA CACACACACACACCCCTACACCTGAGCATTTCTGCCTCTCAACTGTTGCTCAAGCTGTTC CTTCTCCCAGGAATAAACTCCCTCCAAGGCCCAGCATAAATTCTCCACCTTCAGGAATCC TCTGGTCATGCTGGGATTGATTTCTCCTTCTTCCAAACTCCCACTTTGTTTACATTCCTT ACTACATTTACCATAGTCAGTCTGATTTCAGTTATTTATGTACTTATCTATCTTCCCAAC TACACTGGAGGGAGAAGGTTCTGAGAAGACAATTATTTATAGGAGGGCAGGAAATGTGTT GTTTTCCTCTGTGTATATTTCTCAATACCAGGGTCTTGTACATAGCAAGAGCTCAATATG TGCTTACCGAATTGAATCTTTCCATCCTATACTGGGAATCTTTACAGAAAGATCCCAGAC TGAGTTCATTCTAAAACTGCATTTACTGCCTAACTTGATAAATAGGCAATTTTTGAAGTA CATGAATATTCCTAAACTAAGATCCGCTAATACTCATGTGGGCTTGTTTCATTCCTTCAT CCATTCTTCCAATACACTCTGGACTCTTCTTGGGATCTCTCTCCAGCATATAAGGAGACA TTGCTGGGACAACACTTCTCACTCACGGAGATCTGGGAGCAAGCTCTTTGGAGAACTGTT CCACCCCACTGGGTAGGAGGTGACTGCCATTAAAACCACACTAAAACCCAGAGTTGTGGA ATTGGAAAATAGATCTGAATGATCTGCCTTAGTTTCCAAGCTATAACACAGAGTTAAAAA CACTTTTAAAAACAGTGTCTGGAACACAGCAAGTGTGCAATAAATGTTCGATGTTGTATT AACAACGTAGTAGACTGAAAAAACAGAGTCATGACATTTCACTTCTAGAACTATCTCCAC TACTGACTGATTCCTTGTGTAATCTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCGC CCAGGCTGGAGTGCAATGGCACAATTTCAGCTCACTGCAACCTCTGCCTTCTGGGTTCAA GCGATTCTCCTGCCTCAGCCTCCCAAATAGTTGGGATTACAGGCACCCACCACCATGCAC AGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCG AACTTCTGACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCG TGAGCCACACACCGGCCTCCTTGTGTAATCTCAATCAAGTCCTTTCCCCATCTATAAAAT GAAAGTGGCGGAACCAGATGGTTGGTTTCCAAGCTCCTTCTACCTTCAACCATGTAAATT TTTCTCTGATCAAGAAATAACTTTCTCTTCCACATGCTGAGGCTGTTGGCAAGGGAAAAT GTGCATTTATAGCTGCTGGTCCCCAGATGGGAGGAACCACTGTTTCCCAAGGCCAAGGGC AGAGTAAACTGATTAGAAAACCACCTGTGAGCTTTCCCCTGTTTGAACTGTACTATTAAT ACACCCAGTGCAGGTCTCTGAACACAGCATTACCTACCTTCCAACAAAACTCACGGTCAA GGCAAGACAAGAGCCTGAAAACAATGGCTGCAATGAAGAATGCCTGCTTGTGCAGAATTC TTGTACTTTCTTGTTTTTGATGCCTGTAATTAGGGCATCAGTCTAAACTGGGGCCCTCCT TAGGCACAAAGAGGAGGAAAAACACAAAGTCCCATTCTGAACCTGACAGCTCATAAAACA AGGGCCAAACCTAGTAAATAAAAAATGTCACTGACTCACTTAACCACAAACACTGAAGAG GCCTACTATGTGCTGGCCCTATGCTGGACAGAGGAGGAAGGAAAGAGACATGGTCCCTTG CCACCCACGTACTCAGAGTACATATGGAGTGTACATATCCCTAGGCAGACAATGATGAGA GCTATATTAGAGGGTCAGCCTTTGCTACAGAAGATGGAAAGGGGAACAACTAATCCAGCA GAAGGCTCAGAAAAGCTTCACCATGGAGGCCACATGAGATGTAAGAGATGTAAGCCTTGA AAGATGAGGAGGAGGAGGGAAATCCAGGAAGAGAGAATATAAGCAAAGGCTCGAGCAGGA ACATGCAGGGAGTGTTTGAGAAACAGAGATTTGGCCGGGCACGTTGGCTCACATCTGTAG TACCAGCACTTTGGGAGGCCCAGGCAGGCGGATCACCTGAGGTCAGAAGTTTGAATCCAG CCTGGCCAACATGGCGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGT GGCTCATGCCTGTAATTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTG GGAAGTGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGTGACAAAG TGAGACTCCATCTCAAAAAAAAAGGAGAAACAGAGACAACTAGTTTATTTTGACTGAAGC ACAGGTTGCAGGTTTGGGAAAACCAAGGGAAACAGGGAGGGGAGAGGTGTGGGAACAAAT TGTGCAGGAACTTGTCTGAGGCTGGAGTCCAAACTCTACATCCAGCTTGTCCAACCCGCG GCCCTGGATGGCTCTGAATGTGGTCCAACACAAATTCATAAACGTTCTTAAAACACTGAG ATTTTTTTGCAATTTTTTTAAAGCTCATCAGCTATTGTTAATGTTAGTGTATTTTATGTG TGGCCCAAGATGGTTCTTCTTCTTCCAATGTGGCCCAGGGAAGCCAAAAGATTGGACACC ACTGCTCTATATAGTAGGCAATGATGCCCACCAAGGTTTCCGAGTAGTGTCTCAGGAAGA GCACAAGGGCACCCATGAAGAGGATGCAAAAGGAACTAAGTAATTCAATTACTCTGGGAC CACATTACAGGAGACCACATGCACTTTCTAAGCACGTGCTGGGCTCTGACAGCTCCTGTT CACAGAGCTTCCCTCTCCCATGGCTTCGCTTCATGCAATCTGAGTTGCCATCCCCCACAA CTGTCAACATCTGCAAAATACCAGAGTAACAGGACTCCTAACCAACTCTCTGGATTACAG AGAGAGAAGTGTTGAGGTGGGAGCAGATGGGCAGAGGGGGCACCAAAGCCTCTAGCTGGC TCAGTTCCATATAAAACCCAACCCTGGATTTCCTCTTCACATCACTTCCAGCCCAGCCCT CTAATGAAGGGCTGAAGCTAAGGAGAGTGGGCTGAAAGCACCTGGCTGATGGGTGGTGAT CCAGTGAGACATTACACCTACTGTCCAGCATGTGCCTGGCGCATGGGCAGTGGTGCCCTT CCCATTCTGCAGGGTCAGTTCCATCTGTAAATCCCACTGAGGCTTCAAGGCCCAGGTCAC AACAACTCTTCTCTCAGAGCCTTTCTAAAGTACCCCAATCCAAAATGACCAAGCTCCTAG AAATCACAGCTACCATGTATTCAGCACCCATTACATGACAGGCGCCATACTAGGTGACTT CCATATAATCCTATTCACCCTTCACAATGACCCTATTATGGCCATTTCCTAGGGAAGAAA GTGAAGCTCTGGGAGGGGAAGCAGACTTGCCCCAGGACACACAGCTAAGAGGTGGAAGAG ATGAGATCTAAACCCAGGACTCCCTGACCCTGAAGTTGAGCACTTCTAACAACACTTCAT TCCTGTGAGCCTGCCTGCCTCTGATCTGCCACTGTCAGGGAGCTTGGAGCTCTCTAGAAG ACAGGGTGCACCTGACACTCTTATTACCTTTCCCTGTGGACAGCCATCCACACAGGCAGG AGCCTTTAAATACTGAAAATAAATGAAAACAATTAACTTAAAAATAACGCAGTACACAGA TTTCACAAATTCCTCACGTGAAAAACTATTCATGATACTGGACTGCCTGAGCCCTGCGCC CAGCCATAGCCTCGGTCCTGATCCCTGGGAGAGACTGAGTCTCAAACGGGCCACAGAGTA AGCGCCATCTCGGACACCGGCCACGCCCCGACCCCAGGCACAGAGGTCGCAGACAGCTCG GGACAGTCCTGAAAAGCGTCCCCTTAGGCTGTCCCTCCGCAGCTGAATCGCGTCGTGACC TCGGGCAGCCGTGAAGGCCCTGACTGCCCCCTTCCGGGCACACGAGCTCACTCACAGACC CCGGCCCCATTTAGCTCGGAGGAATACCTCGCAGGTCTCGCTTTTACCTTCGCTGGCTCC CGCCGGGGAGCGGTCGCGCGCACCCCTACCTGCAGATCGCTCCTCCGAGAACGCGGAAGA GGCGGTGCTAGATCCAGGGGGTGGGCCCGATCAGAGAGGAGGGTGAGGGGGCGGAGCTGC GCCTGCGCCCTGATGGCTACCCAGGGCCGCCTGAGGGCAGGGGGCTCGAGCTGAGCGAAC TGCGCAGGCGTGACAGGGAAGAGGCGGGGAGAGGGGAGATTGCTGGCAAGCGGGTGGGGC TTAGCTCCTCCGGCGCTTTCTTTTCCGAATGGAGGGTGGAGAAGCCCGGGAAGGTAGGAG GCCGGGCGCGACAGGTGTAATTAACATGTACTGAGAGCTTCTGCAGGCCAGGAAGGAATT TTAAAATGCCTTTTATATGTGGGGAAATGCTGCTAGTCTTTTCTAAAACGGGGGCCAATT CTGTACAATTTCTTTAAAAGTCTGAGTGCCTAGAATTTCACCATAAGAGTTTCTCCTTGA GTACAACATTATCCCCAGTATTTCAAAATTTTTAAAACTTTTAAAAGTTCATTTCTTGGG GAAAAACAACTGTAAATAGGTTAATGCCTCAACCAGTCTCCCCACATCCCCTTCCCAAGT CTGCAGCTGCGATGAGAAAGGATGAGAGTGTGGACTGGGATTTAATTCAGGCGCTGACTC CGAGTGATGGAGGTGAACATCCCTTCCCTGCCTGTCTCAGGATTATCGTGAGGATTTGGT AAGCCAAGCTAGTTAAAGAGCCCCAGGGACTTGCTTCCCATCATCCACCTGACAAACATT TGTTCCCTGTCTTGTCGGGGCTGTCTTTTCATCTGTATGATGGAAGGAGATTGGGAATAT TAGTGAACATTCAGGACTTTGCTAGATTTCCCAATCTGGGTGAAGGCCGGAGAGGCGGAA GATCAAGCTTCTGTGTTCATTCCCTTCTGGAATCCTGCGGTCCAACCTGAGGGCCCCGAT GTATCCTGACTTCTCCCACTCATTACCTTCCGTGGAGGCCGATCCAAGCTTCAAGTCTTC AGAGGCCCTGCTGGCCTGTTCCCTTCCCTGTTGCCTGTGGCAATAGCCCAAGAGATTCAG GACCTATGTTCCAGGTTCTCAAAGTTGCTATGTCCCTCACATGGCAATCAAATTCAGTTA ACATCTTTGAGGGCTCTGGGGGTGCTCAGAGGAAGGAGGGCTCCCCCAAAGCAGGTGGAG CTCTAGTCATGACTGTGGCTTATTTCACCACATATTCCACAGCTTGCTGTGGGGTAGGGA GGAGAGGCAACAGGAAACCTCAGAGGCTGCAGTGTTTATGGGAGCCGAGGGTGATGCGGC ATCCTTTACTCAATAGGTGGATGCTCTGCCCCAGGCTGGAGAGGATGGCTTACTACCTAG GTCCCTGCTCCAAATATTGTTTTGGAATTTTTTTTCTTTTTTTTTTTCTGAGACAAGGTC TCACTGTGTTCCCCAGGCTGGAGTGCAGTGGCACCAGCTTTGCTCACTGCAACCTCTGCT TGGGCTCAAGTGATCCTCCTGCTTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGCACT ACCATGACTGGCTAATTTTTGAATTTTTTTAGAGGCAGGGTTTTGCCATGTTGCCCAGGC TGGTCTCGAACTCCTGAGCTCAATGATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATT ACAGGGAAGAGCCACTATGCCCAGCTTTGTTATGGACCTTGAGCCAACAGGAAAATAAAG CCCAGCCTGACTTCTCAACCAAGCTGCCACTCTACCTCCCAGGACCCTTTGTTACTAGGT TTTGCCCCATGGGAGTGTGCTCTTTTATCTGCATCATTGAGGCCCTATCTCTTTCTTTTC CCCTTCTCTTCCTTTCTGTCTATTCTTCTTTAAGCATCCCTCTGTGAATCTCTCAAAGCA ATTTTGTGTCAGCTTCCTAATGTATTTACAGATATTCTCATGTAAGGTGCAGGTCTTGGG TCACACAGTTCTAAGATAAATCTACTCTCACTGCCATGGTCATATTTCAAAATGACCATG AACCCAAAGCATGGGACTTGTAACAGTCTGAGCTGTCCAATGACAGAGGAGGTAGTGAGC GATCTGTTATAGGAGGTGTGCAAATAGCACCCTTTTAGAATGCTGGGATTGGGCCTCCTG TGGTGAGCCAGAGGAAGAGGCAGCAGAATGGAGGGCCTTCCAGATTCTAGAGGAGTGACT AAAGGCAGGGATATTGGGGGCTGGAAGGGAAGCAAGGCAGCTGGCCAAAGACACACTTGA TTCAACAAGCTATTATATGTCAAGCACTTAGAAGTGTACCTGACACATAATGAACATTAG CTGTTATGATGACTGTGAATGATTCATAGACTATATAATGAAGGAGCTGAGATCAATCAG TCCTTCACTCCCATCACTGATAACAAAATAGATGAAGGGTTGGGGTCTAGAGGGGGAATG GGCTTGCAATGGAACTTCAGGAGCTGGGCTGGGGCTACAACCTATGCCTTTGCCTCCCAG GAGAGCCTCTGCACAAAGCCAGGCTGGCTCCTTTGCAGGAAGAGGGAAGAGCTCTAGATG GGCCTTTGTTGACTCTTAAGAACCAAGCTGCTTTTTAATTCCTGCCCAGGCAGCTTGTGA GTTGGGGCAGTGGAATGACAGCAAGACCTGAGCCAATAGATGCAGATGTCTACTGGGGAG TAAGCTCAGGAGTCAGGCCCATGTCCTGCCACCCCCACCGTAGCTCCAGCCAGCAACAAG TATCTTCCTCTTCAGGATGGCCTCCTGTCCTGTAATTAGTGTTGGGATTGTATTTCCACT CTGTCCTTTTATCTACTACCTCAAAAAAAAACCACCCAGAGTAAGGGGCTGGAGTGAGAA TAGCCAATGCCAGGCCAGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCC GAGGCGGGTAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACGCGGTGAAACCC CGTTTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGGTGGTGGGTGCCTGTAGTCCCA GCTACTCCGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGAGCTTGCAGTGA GCCAAGATCGCGCCACTGCACTCCAACCTGGGTGACAGAGCAAGACTCCATCTCAAAAAA AAAAAAAAAAAGAAAAAGAAAAAAAAGAATAGCCAATGCCAGGCAACCTGAGATGAAACA AGGAACGATTCCTATCAGACTGAGTTCCCGGAAGGCAAAGAAAAGCCAGGCTTCTCCACC CCAAGCGTCCTAGCCTAGCTCGGTCTAGAATTTCCAGAGCCCCAGGAGAATCTTTGTGTC CCCACCCTAGAGAGCTGGGCCAGACATGACCACACCAGCCAGCCCTCCACATGGTCCAGT ATCTCAGGACAAAAAGCCTTCCCAGCCCCATTCTGGCTCAGTTCCTTCCATGGTCTGCCA AGAGCCATGTGGCACCCAGATCACCGCTTCCCACCAGTGGCTGCTTTAGTTTGCCTTTTA TTTTACCAAAAATAACAACAATAAAGTCTTCCCTCTGTTTCATAAAAATAAATTTTCCAA CCCTCCCCCTATCCCAGAAATCAGCCCTTGCCACAGCCTAGAATCCATCATGCAAGTCAC AGCACTCTGGGAAAAGCTCCTACTACCCTCGCTCCACAGCCTCTGGCAAAGCTGCCAGGC CACTCTGGAGGCGGCAGAGGCAGAAGTCCCAGGCCCAGCTGGCTGGGCCCAAGAGCTCCA TCTGTTTCCCCAAAGTACAGGCAGCTTCTAGGCCATTGAGTGGGGCATGATATTGGATGC TTGGCTCAGGAAACAACCCCAGCCAACCCAAGGGGCAGTGGGACATGTTGGCCTCAGGTT AGAAATTATTGCTCAAAGCAGAAACAGTTGTGTCCTAGAGAGGGTCTGTTAAACCCTCTT TCCATGTGTATCTCTATGTAGCAATTGATGGGCCCTGCGGTCAGGATCCCTGGTTTCTCC AGCTCCATGAATGCCTCCCTGTGAGGCCCTGGACAGTTTCTCCCTCTTCTTCTCCTGGCT TCAGTTTCCCCGTATGTACATTGAGACAGTAAGACTGGATGATTCTCAGGTTCCCTCTGG CTTTCCATTCTGGCATCCCAGAGTGGAGGCTCTGGGAGGGCAGAACCCTGTTCCTGCCTC AGTTTCCCCACCTGTGGGTCTGCGTATAGGGCTGGGTATGGAGGTACTGAGTAATGGAGT GCTGCGTGAACATCCCAGTCTCCCTGTGGATAGCTGTGCTGTGAGATCCAACTGGCTGGA ATGTGTCAGGGATGGCTGGGAAGGAGGCAGGTACTTTTAGGATGGAGGATCTCCATGCCT GGAAGAGTCCATTCACCAACTACATCCTCAATGTGCTGGGATGGGAGACAAGACTCCAAA GTTCCCAATTCAAGTTCCACAAGCTCCTTGGACGGGGAGATTATTTTGTGCTGGGCTTCA GATCCGAGGAGCCAGGTCTGTAGATTCTGGGAGCTAGAGTGGAGTATATGATTCCCAGAT GAAGGGCCAGGGGACCTTTGTGTACTTGAGGGATCATCTCCAACCCCCAGGAGGACACGT ATAATACAGGCCTTCTTGGAGGCAGAGGGATGAGTAAAATGTCAGCTCATGGGCATCTCT GGGTAAGAGAATCAGAGCCTGTGTCTGCAGTGGGTCGGTTTAGGAACTCAAGGCAAGGCT CCTCTTCCTACGTTCCCCCAGCTCTCCAGGACTCATGCTGATGGAAGAGTGTAGCCTGGA AGGTTTGAATGTAGAGCAACATCTACAACCACATTTTTGTGCACTTACACACATGGTCAG ATACACTGAGTGGGGACGCTGAGCTGTCATCACTCCTACAGTGGTCATGGTCTGATGGTC CCATGGTCTGATGGTCCCAATCTATTTATCCATCCATCCAACATTTATGGAAGGCCTACT ATGTGCCAAGGAGGGGTAAGGCAGCTAGCTCTCACAGACACACCCCACAGTGAAAATCAC ACACACACACACACACCCCGGCATCTGTGCTCACTCACAGGCAGACTGCTCACTTTCTTG CACCTTTCTTGCCATCACCTCGGCCACACCCACATTCCTCCAATAGGCTTGGGAACCAGC ATGGAAGGGTCAAGTGTCATAGAAGAAACCCCCTAGCCTACCCTACTCCCAGACTTCATG CCAGAGGTTTAACTCCACTTCCCTTCTGTTTGCCTGCCTAGATGCTCTCCCCTTCTCCAT CCACAAGCGGTCAGGGCGACAGGTAGGCAGACTCCTGAGAACCAGAAGTCCAGAGGCTTT GGGTGTGTGGAGTGATTCCAGTGCCTTCAGATTCCTTCAGGCTCCTGGGGGTCCCCTCTG CCAGCCACCCTATGTTCAGATCGTCCATCTGATGGCCAAAAAAGTCCAGACCTGGGCTCA GTGGCAGATCCGCTCTGTCATCTCCCTCTGTAGAGACACAAGGTAGGGAGGGGTCAATTA GAGCTCAGCCTACTAGGCAATCCCTTCCCAAACCATAGGGCCTAGCTGCTCTTCTGTCTG AGCCTGGCCTTCCCCCAGCAACCCCAACTCTTAGGCTGCAGATCTGGGTTTGTAAACCAA CACTTGAATGAATTCTCTATTGAAGTACAGAATTCACTGTTAAATGAATTGCCTTCCCCT AATTCATCTACTTGGGCGTTGGAGTTACTTAAAGCAGGCAGCTTTTGGACGTGAAAACTC AGAGGCTAGCCTTGGTAGGGGAGGGTGGTAGGGCTTGGCCTCACCAGTGGCTCCAGCTCC CGCTGGTCCACCAGACTGAACTCGCGGATGAAGTAGTAGAAGTGCTTGTAGCAGGTGTTG ACGTGCGCCTCTGCCCCCATGCTGAGGATGCTATCGAAGTGGTGGATGTAGACATGGACA AAGACTCGGAAGAGGCGGGTCAGGATCTTGGTGCAGACCTGCTGGAAGTTCTTAGGGAAG GGAACTCCTAGAGGGCAGGGGAGGGCAGAAGGGGATCAGTATCCTGGTGCCAAAGCTCTG CTCAACTTTTCCCTCCCACACACAGGCAACCAGGATGGCTTTTTCCCCAGCACACTTTTT AGTACACTTCCCTTTGGAAAACAGAGAGTGGTTTGACTTTCTCCCATACTTTTCTTTCTT TCTTCCTTTCTTTTTTTCTTTCCTTTTTGAGACGGAGTTTCACTCTTGCCCAGGCAAGTG CAATGGCATGATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGGTATTCTCCTGC CTCAGCCTCCCAAGTAGCTGGGATTACAGACATGTGCCATCATGCCCAGCTAATTTTGTA TTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCA GGTGATCCACCTGCCTCGTCCTCCTAAATGCTGGGATTACAGGCATGAGCCACTGTGCCT GGCCATACTTTTCTTTCTAATGAAGCACAAATCTGACTGTGGCTCTCCCCTGCTGGAATA TACATCATCTTCCACATTTTCCCATTACCTAAAGCAGGGCTTTGCAAACTTGTGGGGGTC ACTGACCAACCCTTTTTAGACTATGATAAAAGTTACGACCTAAACTCTCCCCAGAAATAT GTGCAATTGCAGAGATGCTCACATCACACTCTTGTATACAACTCCAAGGAGAGTTCAACA ACTGGGTCCATTTAAAAAATCCCTGGGCCTTCAGGATTAAGTCCTAACTTTCCAGCAGGA CGCTGCTCAAGGCCTTTCATGATCTTATCCTGACCTCCCTCTCTAGCCCCACCCCATGTC CCTCCTCTTTTCAACATTCACACAGAAGTCCTCAGACCCCCAATCCTGGAAATTATGAAT TCTGCAAGAGTTAGTTCAGACAGCCCTCATTCCTTCAAATATTCAACAACACGAAGAACC TTCCATTTATGAGCAAGGCCTTGTGCTGGGCCCTTCACACCTTTTGCCTCTAATCCTTAG AACAATTCGCCTGATGTGTCTGATTGTCACTTTAGATATGATAAAACAGAAGTGCTTATA AAGGTGAAGCTGCTAGCCCAAGGCCACATAAGTATTAATCAGTGCAGAATGGAGACTGGA TTCAGACCCTCTTTGCAGTGCACTGCAGCGACCCTCACAGATATTGGGACCCATGAAAAA GGCCCCGCTTCTGCATAGTCCCCCATGCTCAAGGCAGAGATCTTGGTGGCTTATGCCCTC TTCTCTGTGTGGCAGTCACCCAGGGTTTTAGGCATCGATACCTGGAGTCCCACAGGCCCA GGGAGGTATGGCCAGCAGGGACTATGAATCTACATTCAGGTCCACAGCTGGCCCACCCGG CTCTGTAGACCCCCTCCTCTTCCTCACCATTCCCAGGTGGGGTCGAGCCTTCCCTCCCTC TGAGCCCCTCCAGCCCAGCCCAGATTCCTCAGACATATCCTGCCCATGTAGACTTGGGGT CCTGGGCTCCCACAGATCTGAGCCCCAGTTCGGAATTCCTCCCAGTTCAGTGCACTTTCC CTCAGTAGCCTCAAGTTTCCTCCTATGTAAAATGAAGGTGCTCCTTGTCGGGCATGACAG TGCAAGAAACAGCAGGCCACTGGCTGGGGAGGAGCCGTGGGCATTGAATTGTGACTCAGT GCCCAGCTTCCTTCAGCATTCAGACTTCTCCCCTCAGGGCTTGACCACCCTGCCCCACCC ACCGCTGATCCACACAGCCTCTGCAGAGATGAGCTCCAGGCCAGGTGGGGGCTGGGCCCA GCTACAGGTGCGGCTGGTGTGATGAACACAGTGTCATGCCTGCTCAGCTCCTGGACCAAC AACCCCCTCCTGCTGCCCTCGGGTGGGTAAGCAGTGCCTGGGTGACATCACTCATCTCCC CTCCCTACCCTCACCCGCCCAGGCTGCCCAGCTGAGATAAGAAAAGGCCCCACAGCCTGT GCCTGGCAAGGGAAAATTCTGTCCTCAGAGCCCCAATCTGAGGTGATGATACCACCAGGG CCCACCCAACCACCAACTCCCTCCTTTTCCTGAGGCCAGGAGTCAGAGGGAACCCCGGGA GGCTGGAGGTCAAATCAGCTATGAACACCTCGGGGCAACTGTTCTGGAAGGTTCTGAGAA TCACAGCATCTGTGGTCTTGCCAGAGTGGTCCTTGGTGGGACCACTTATGCTTTAGAAAA GAAAAGCCCTCTGAGGTGGGTGGATCACCTGAGGTCAGGTGTTCGAGATCAGCCTGGCCA ATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGTG CCTATAATCCCAGCTACTCAGAAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGGGGCAG AGGTTGCAGTAAGCTGAGATCTCACCACTGGGTGAAAGACCGAAACTCTGTCTCAGAAAA GAAAAAAAAAAAAAAAGAAAGAAAGAAAGAAAAAGAAAAGAAAGAAAAGCCCCAAATTGG GAGTCAGGAAGTCCTAGCAAATGCTTGACCTTGAGCAAGGCACTTAACCTGTTTCAACCT CGCTTTCCTCTTCCACAAAATGGGGATGAAAATCAACCCCCAACCCTGCAGAGTGTCTAT ATCAAACTAAATCCTCATCTGTGGAATGGGCTCCCAGTGGCTCCCTCCCCGCCAGGTGAC ACTCACCAACACGCGTGGGAAAGACCTCTTCGTCGTTGATGAGGCCTTCGATCCAGTCCA TGAGCAATGCCATATAGCGCGGCGCAGAGAGCTTGGCGGGCCGCCGGTACTGGCGCTCGT CCTGCCAGCGGTACTCGTAGCGGGGCCCGCCGGCCATGACCGGGCAGCTGGTCTCACTGC AGCGCTCCGCCATAGTGCCGTAGATGAGGTTGATGCGGTTGAAGAAGTCCACCACGTGCA CGGCGATCCAGTCGTCGATGTTCTCCCCGGGTGGTAGCCTCACCACACTGCGCAGGTCCA GGCCCGACTTGAGAGAGGCCTGTGCCTTCTTGTACAGCTCAAAGCGCTGTGTGCCCGGCT CAAAGCGCTTCCGCGGCCGGAACGTCTTGTCCTTGGCGAACACCTGCTTCAGGCACAGGG CCATGGCCAGCTGGGCCTGGGGCTGCTGTCCAGGGGCTCGGACCTGAGGATACCCTGCCA GGGACAAGGGCATAGGGGAGCTGGCGGTCAAGGCCTTATCATCTGGGCTCTGACTTCCCA ATTCATCATTTCCCTGTCACCTCTCAGCCTTTGCTCAACCTCTGCATCCTCTGCCTGGAA TCTAAGTCCTCAGCCCCTAGGTCCAGTGCCCCGCCCTCTTTCCAGGCTATGTTAGTCCCC CTTGCTAAGCCCCCACAGTCCTCCCATCTTGCTTTGTCTCTTTTCTGCTTTCATTGCAGA GCTGGGCCTGGGCTCTAAACAGGTGCCCCTCAGACTTGCTGTTGGTCACGAGAGAGGTCG CAGAGGCTCCCTGCAGGCCCACCAGCAGACAGGGGCTTGGACGAGATGACCTCTGGGAGC CCCCTTGGCCAGCTGGTGCAACGTGGGAGAGCCTCGCAGCATTGTGCTGGGGGCAGGGTG GAGGGGGGTCGGGGGTGGCTTTCGGCTTCCTCTGGGATATCCCGTAGTCCATCCGGCCAC CGGGGATTCCCAGGGAGCAGCAGGGAACTTTTCTACCAAAAATGTCCTTTCCTTTTTTTT CACCCTGAAAGAGGAAAGGGCCCTCCCGCTGCCAGCTGGGCGGCTTCTGAGTGTGGCTGC AAGCACTGGAGGAGGGGGAGGGCGGCAGGCCAATGAGGGCGTCGCTTCCTCTGACAACAG CTGGAGATCCTTCCCCTCAAGCCAGCCTCCTCCAGCCCCAAATCTGAACAAGCCACTGGC TCCTCCCGTTGCACCTGACACTCAGTAGACATTCCTCTAGCAACTACTATGTGCCTGGCA CTGGGAGGTAGAAGAGTATAGTCAGATGCACCCAGGAGGGCCCATCTAGAGCTCAGGCAA ATTTACTTTGCCTCCTAGAATTTAAGGATCCCAGATTCAGAACAAATTTTGGGAGACAGT GATCAGGGCCCTAGGCTCAGAGGCAGGAGTCCTGGGTTCTAGTCCCAGCTCTACCACTGG CTTACTGGGTGACCCCTGTATCACCATGGATTTAGCCCATCCAGGTCCTGGGTCACTCTG CTATAGCTAGGTTTCTAAGACCTGAGTCATCTCATCTCAACTGTGAGTGTGTGAGCTACT GGGAAATGCAGACCCATGTACCTACCAAAACTAGAATTTAGCCACCCACTAAGCACACTG CCCCTGCCCCTAGACTGAGCACTAAGGCTGAGTATAAGCTAAGAATTGCATTCTGGTTCC TGGCTGACCTCTGACCTGGGCTCTGGCAAGTGTGAGCCCTGACTCTAGCCTTTAGCCCTA CCCTGAGGCTTGCTTATGGCCAAAGCCTGGGCTTGACCTCTGACGCTGGAGCACTGTCCT TTCTCACATCTCTGGTAACCCTGGGACAGGATTGGGGAAGGGAGGGTGGGAACCAGGTGA CACCTGGGTAAAAGCAAAGGGATGGCACATATTTCGGGGAGGGGTATTACTTCTGGCAAG AAGTCAAACTAGCTGGGGAGCTGTTTGAGACAAAGGTCCTTCCTTGAACCCACAAAGGCA GGCCAGGATGGGGGCAGTCTGGTAAAATGAGAGCAGCTTGGAGAGTAGAAACAGGCCATT CAGCAGGAACTTGTTCTCTTGAAAAAAACTCACAGATGTGAAAGGTCATCTCATCCATCC CGACTCTTCGACTTCTCACCCAAAGAAGTCCCCAGGGTGGGACCCCAGTTTCCAGAGCAA AGAGATTTCTGCGCTTCATTTGCCATCTCCATTTTAAACTCTGCTTGGGGCAAGTGCTTC CAAAATCCCTCACACTGCAATTAGGCGGGGCTCCTGGGCTCCCCACATTGCATGGCCCCC TTTATGACAGTTAGAAATAGGCCCCCACCCTGGCATTCAGCACCTTGTCCTACCTTTCCT GCCCCACTTCCCACCTCCCCACACCAACCACCCTGGGCTTCTTCCTGATTCCTGAACACG CCCCCACTCTTTTGCCTCTGCATGTTTTCTTATCCCTCCACCTGCCTGACCACACATCCT CAGATTGGCTGCTACCTCCTCCCACAGCCTCCTCTCCTGAACTCAGATCTCCTTCTCCTT GGGTAGAGGCTGCTTTTGGTCATTGCAGTCTCCACTCCATCCCCAACCCACCCCCAGCTT AGGACAAGGCCTGGCACAAAGTCAGTGTTCAGGCTTTAAGGAAAGCTTAGACTAGAATCT TAGAGTTAAAATAGCCCTGATAGATCAGCTGGCCCAACTCACTTGTACAGATGGGGAAAC TGAGGCCCAGATGAGGAAACTGAGGCCTAAAAAGAGGACTTGAGGAGCCTGTGTCCACAT AGCAAGTTACAAGCAGAACTGGGAACTGGGATAAGGTGGGGCTCAGCTCATGACCAAGAG TAAAAGACCATTTTCCTGCACTGGCTCATCAATGGTCTGGTGGAGACAGAGAAGAGGAGG GGAGTGGAGGGACAGTGGAAGCATCTTCTCCACCAAACAGCCCAACCTGCTTCCTGTCCC CAACACACTGACTCCGCACAGCAACTGGGGTGTCCTGACCAGTGAGCTAGAGTTCCACCT TACTCCTGTGGAACTTCAAGGCCTGGGTCTCTTTCCAGGAAAATGTAAGCTCAGGGGGTG GGTGCAGGGCAGGTGCTCTTCTAGCCACAGGGTTAACTCCCTTCACTCCCCACCCCCATG CCCTCACTGAGTTTCTATCTGTCACAGAACCTCTGTCTCTCCCTGAACCACTGCCGTTCC CCGTCCTAGCCCCCATTTCCCAGTGATGGCTATCCTTTCACTCCTGGAGTGGCAGTGCCT TGCTCGTTCCCTGGGTGCGGATCTGGGCTTCTCAAATGAAGACAGCAGGCTGACCCTACC TGTTTCTGATATTTAGCCCCCTGCTAGGCTACATCTACCACTCCTTGGGCCTGGCCCAGG ATCTGGGCCAGAGGATGGCCCCAGTTTGAACCCAGAATCCATCCTGGGACTCTCTCTAGG ACAGAGGTCGAAGAGAAAAAGTAGAGGCGAAGACTCCACGCTCTCCTCGCGGCGCGCAGC CACCCACGCCCACCCCCGGCTTCCCTGCAACCTCAAACCAGCTCCCAGGGCCAGGAAGGT CGTAGGACCCAGAGGAGCCCGCCTGACATTTCCGCTCCCCGAAAACACGCCCCCCAACCC CTCCCCTCTGCCCCGTACTCCCCCACCCCGACAATCCCCCCCGCAACTTTCGAAGCTCTG AGCCTCGGACGCCAGCCTCAGGACAGCGGCCAGCCTGCCTTCGGGCGGGACTCTCCTCCG GACTGTGCCACGCCAGGACGGCCGAAGAAATGAAAGTGGAAGCCAGGCGGGCGGGGTGCG CGGCGAGGCCGCAGGGGCACGGCGCACACTCACGGGTCCTCTTCTGGCCGTGGGGTCACA TTCCCAGCCACAGGATCGCCTTTCTCCTGCAGGTCCCGCAGTGCCTGTTCTCTCTCCTGT CAGCCTGTCCGTCTGCCTGTCCTGCCGGCCGCGGCTGCCCTCCTGCCCCGGGCGACGCCA GCTCCG bcftools-1.21/test/csq/ENST00000528237/ENST00000528237.fa.fai000066400000000000000000000000211467060157400215360ustar00rootroot000000000000001 59466 23 60 61 bcftools-1.21/test/csq/ENST00000528237/ENST00000528237.gff000066400000000000000000000050351467060157400211660ustar00rootroot000000000000001 ensembl_havana gene 21 59446 . - . ID=gene:ENSG00000079277;Name=MKNK1;biotype=protein_coding;description=MAP kinase interacting serine/threonine kinase 1 [Source:HGNC Symbol%3BAcc:7110];gene_id=ENSG00000079277;logic_name=ensembl_havana_gene;version=15 1 ensembl_havana transcript 14712 28862 . - . ID=transcript:ENST00000528237;Parent=gene:ENSG00000079277;Name=MKNK1-022;biotype=protein_coding;havana_transcript=OTTHUMT00000387152;havana_version=1;transcript_id=ENST00000528237;version=1 1 havana exon 14712 14770 . - . Parent=transcript:ENST00000528237;Name=ENSE00002192432;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002192432;rank=7;version=1 1 havana CDS 14712 14770 . - 2 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 1 havana exon 17550 17623 . - . Parent=transcript:ENST00000528237;Name=ENSE00003471601;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003471601;rank=6;version=1 1 havana CDS 17550 17623 . - 1 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 1 havana exon 19178 19257 . - . Parent=transcript:ENST00000528237;Name=ENSE00003580253;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003580253;rank=5;version=1 1 havana CDS 19178 19257 . - 0 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 1 havana exon 23133 23230 . - . Parent=transcript:ENST00000528237;Name=ENSE00003517498;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003517498;rank=4;version=1 1 havana CDS 23133 23230 . - 2 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 1 havana exon 25831 25932 . - . Parent=transcript:ENST00000528237;Name=ENSE00003482318;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003482318;rank=3;version=1 1 havana CDS 25831 25932 . - 2 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 1 havana CDS 28477 28492 . - 0 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 1 havana exon 28477 28577 . - . Parent=transcript:ENST00000528237;Name=ENSE00003620146;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003620146;rank=2;version=1 1 havana five_prime_UTR 28493 28577 . - . Parent=transcript:ENST00000528237 1 havana exon 28837 28862 . - . Parent=transcript:ENST00000528237;Name=ENSE00002159407;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002159407;rank=1;version=1 1 havana five_prime_UTR 28837 28862 . - . Parent=transcript:ENST00000528237 bcftools-1.21/test/csq/ENST00000528237/retained-stop-incomplete-cds.txt000066400000000000000000000002451467060157400250770ustar00rootroot0000000000000014714 G A stop_retained|MKNK1|ENST00000528237|protein_coding|-|143R>143*|14714G>A 14714 G A stop_retained|MKNK1|ENST00000528237|protein_coding|-|143R>143*|14714G>A bcftools-1.21/test/csq/ENST00000528237/retained-stop-incomplete-cds.vcf000066400000000000000000000006621467060157400250410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 14714 . G A . . EXP=stop_retained|MKNK1|ENST00000528237|protein_coding|-|143R>143*|14714G>A;type=ENST00000528237:47037783-G-A bcftools-1.21/test/csq/ENST00000536784/000077500000000000000000000000001467060157400166615ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000536784/ENST00000536784.fa000066400000000000000000000365621467060157400210370ustar00rootroot00000000000000>11 11:60704556-60720002 TCGTGAGGAAGGGCTCATGCCCCTTATTTATGGGAACCATTTCATTCTAACAGAATAAAC CGAGAAGGAAACCAGAGCTGGGACTGCTGCCGTCTGTCCGGTAGAGTGAAGCAAGGGGGC TGGAATAGGGCCTGTTCAGCCCCTGTCCCTGCTGAAACGGCTGTGGGAGGCTGGGCCCTG GGACGCCCTCTCATAGCGTCCAGCGATCCAGACAAATAGGAGAGCCGTGACGGCCTGAAT GCCAGCCAGCAGGAAGAAGTAGAGGTCCATCCGGCAATTGTTGATGTTCCCTGGGGAAAG GAGGGGTTAGATTTGGGTCAGGACAGGGATCCTCTGTCTTGCGCCCTGTGCCTGCCGTGT CCTAGCCCTGGGGCTGGCAACTGAGGCCATGTGGGCAGTGGTGGGATCTGAAGACACTGG ACAGATACCCACTAATGTTTGACTTCCTGAAGATCTCCAGGGGTGTCTACAATTCCTCTT CAGCTATTCAGAAGGGGGCGTGAAATATAAACACCATGAGAAAGGTAACCCTTCAGCCAG AGATGGCAGAGTTCCAGAAGCAGAAAGGAGCCTTGGAGGTCCACTAAGTTCAACACTTGG GGAAAGAAAGGCCCAAGGAGGGAGGCCACGCTGTGGGTGACTGGCCAAGCCCGGGCTAGA ACCCCATTCTCCCAAGTCTAGCCCTCTACTTGCTTCTCCCCAGAGTCAAAGCACTTTAGC AGTTGCCACCTCCTTTCCAAGCCTCCCTCCATCCATGTCCCACTCCTGGGGAGGCCCCAT ACTCACCAAAGTCCTTGGGGCAGTGCAGCCAGCCCCCGGGCAAGGACAGCAGTGCCACTA GGCTGGAGCCCAACAGTGAGCCCACCCCCGACAGGCAGAAGAAGATGCCCATGATGGCAC CCTGCATGGAGCGCGGGGCCTCTGAGTAGGCAAACTCCAGGCCTGCAGAGGGGGAGCAGA GACGATCTCAGGGGCTGGTGCAGGCGCAGAGAACAGGCCCAGGCCCCTGCTTGCTGCCCC TGACCCTGCCCCCACCAAGCCACCCTCCAGGCTTCCCCTGGATGCCTGTCCACTCAGTGG CAATGACAGCACCCATGCATCAATGCCGCCTTCCCCTCTGCCCTGCTCACCTGCCTCCTG GCTGAACCCCTGCACCGGGGTACTCCATGCGCTGCCCCAATAGCTCTGTCTCCCCTCCTC CCCTTCCTGCCAGGTCTATCATTTCAGTGACAGCACCATCTTTACCTCCTCTCTCTCCCC ACCCTCTCTGCCCACCTTCAACGTCATCGTCAAATTGTTTTGATACAGCCTCTGAAATCT ATTCTAAATATATGTCCTTCTCTCTATTCCCTCTGCCCTGGGTCCAACCCCAGCCCTGGT CACTTTCTGCAAATGCCTCTTAAACTCCCCTGACTCCTGTCCTCCTCACACAGCCAGGAG CATCAGTCTAAAGGACCTCGGATGGGGTCCTTTCCCGGCCAAAACCCCCTGGAGAGGAGG GGCGCTGTTGCCTTCAGGAGAAATCCCAAGGTGCAGGCTCAGCGCACAAAGCCCTTCGAC ACTTCGGCTCCCTGCACCTCCCATGCCTCTCCAGCCCTATCCCCCACGCTTCCCAAAGGC TTGGGCCTTTGCTTATGCTGTTCCCTCTGCCTGTAAGACCGCTCCTCCTACCCACTCACC TGCCCGCCTCCTCTCCATGCTTAAGGGCTCCCACTGCACTCTGCCCTGACTTCCACAGCA CTCCACTGGCTCACTGTTTGCCTGACTCTCTCCCCATCTGAGTGAGCTCCCAGGGTCAGT CTTTTCTTTATGTCTGACCCAGCCTAGCCCTGGGCCCGCAGCTGAGGAAGCCCTTGCTTT TTTGCTGACTGAAGGGCCTGCCCCAGCCTTGCAGCTCTAGCTCCCAGCCCGGGGAAGGGG GTTGGGAGGGTGGGGAGCGAAGGACATAGAAATCCATTACTATGACCCAGAGTACTGTGT GCTATGATAGAGAGATGAACACGGGGCGGGAAGGGAGGACCCCTTCTGCCCAAGGACCTT GGTATTTAGGCTCAGAATTGAAGGGGATATTGGAGTTCACCTTCAGTCTAAGGTAGAGGG AACAGCAACTTCAAAGACACAGAGGGTGGAGAACCTGGCACCAGGGGAATACGTGGAGAG CTGGTGTGGGAAGTTTCTTGCTCGCCTCCAAATCCCCAGTGCCTGTCACATAGGGGCTGA CTTGAACCAGGTGCTAATTATAGACCCCCGTTGGGTGAATGAGCCCTGGTCAGAAAACAC TGCCTTCCTCCATGCAGATGGGCCCTGGGGGCTGCATCCCTGGGGTACCTGACTTTGAGG TGCCACCGGGCAGAGCCCATCACTGGTGCAGGAGCAGGGGAGGGGATCCAGGGTACCTGG GATGCTGGCAAAGATCTCACTGATCCCAATGAGCAGGTACTGAGGGATCTGCCACCAGAT GGACAGTGGTGCCGCGTTGTACAGGACCTCCCCAATCTGCTGGGACACGGTCTCGTTGTG GTGGATGTAGTGTAAGCGCTCCATCTCCAGGACTCCTGGTGGAGGAGCAGAGGGGGATTA TAGTCAGGCCCACCCCAGGCAGCTTAGCCCACAGAAGAGCTTGTACATGGTGGGGATGGG GTACTCATGAAGCAGCCAAAGATTGAGCAGCAGGCAAGGAAAAGAATGCTGGACTGGGGG GTGGAGGAGGGGGCCAAGATGTGACCAACTCCTCCCTTTTGGTCTTGGCTGCTAGAAGCT CCAAGCTGAGTTTTGCACTCAATAACACTAACAACTCTCATTAATGGAGAACCTGTTATG TGCTAGGCATTTACCATGCATCCTTGCTGCGGAAGAAAGTGAAATAACTAGCACTTTCAA GTGCTTAACTAGAAAGTTAAGCAACTAGCCCACAGTCACACAGCTGATAAGTAGTCAGGG CTGGATTTGAGCTCTGGTATGTCTGGTTTCAAAGCTGGCCTACTTTCCATGATATCACAT GACTTCTCTACTGCAACGTCAAGTATTGCTGTAGTGTTTCTAACCTGGCTTTCAAGTTTA ACTATGTTATCTCCTTCTCCTGTGTTGCTTGGGAGATAGCTGTGCTCTAGTGGAATGAAC ATTGGACATGGAGTTGGGGGACCTGGGTTCCCAGCCTGGCTAGCTGTGTGACCTTGGGCA AATCACTTAACCTCTCTAGACTCAGTTCCCTTACTCAAGAAGCAGGAATAACATTCCCAG GATTATTGTGAGGATAAAATAGGACAAACTGCTTTAAGGATATAGCTGGAATAAAATCTA GTTGGGTTTTCACACTTTCAACACAATACCGTTTATGGAGCTTTCATTTCTCCAGCTCAT ACTTGTGATCCAGGCACACTACTGAGTGCTTTACAGACTTCATCTGCTGTAATCCTCACA ACACCCCCCATCAGACTGAGTTCCACAAGGGCAGAGCCCTGCTCAGGGTCCGAATGACAC CTGTCCCCATTTTAAAGACATAGCTCAGAGACTCTAAGGAACTTCAGGGTCATAAAGTTA CTAAGTAAAAAGGGTTCAGGTTTGTGCAACAGTGTGAAAGACTTCTTTAGCTGATCCCCC CCACTGCCCCCACCAACCCCCACTTTGTAACAAATGGCTTCAGATCCTTTTGAAATGGAA GAAGGAAGATAATTTTTTTTTAAGTCTTCATTTGCCACTAAGTGGAAAATTCATTCAACA CATTTATGGAGGGCCCACGTGCATGTTCATAGCAGTGAATAAAAAAAGAAAAACTATCTC TGCCTTCAAGGAGCTGATAATTCACTGGGGGAAAATATTTGTTCCTCTCTCGGCCTGAGT TTCTTCTTCTGTCAAAATGAGGGGCAGCTGGATTAGATAGGAGGGTCTCTTTCAGCTTGC ACCTCTGGGAAGCCAACACTGACGCCCACTGGGAGAGGCTGAACTTGGTCCAGGCTACCA CTTCAGCATCAGCCCATGGTGGAAGCAGACTTCCCCAAGCCCAAAGTTCAGCCCCCTGCC CCACACCCCTCTGCACACCTGCCACAATGACGGAGGTAAAACCAAAGAACATCCCCAGCG CCATCTTCTGCAGAGCAGAGGGAAGCAGCTTGCACCGCAGCAGTAAAGGGTCGATCAAGC GGTCCTTCAGAGGGACCAGAATCAGCACCACCACAACATTGGCCAGGAGGAGCCAGGCTT CCGGGATCTGGGCAGGAGGAAGTCAGGAGAGGCAGGCTAGCAGAGTGCAAGGAGCCTGGC TGCAGTCAGGAGACCTGGACTCTAGACTGGCCCTGGGTGACCCTGGGGTCCAGCTCCTTT CCCTCTCTGGAGTTCATGCTCCTCAGCTGTGTAACCAGGGAGTGGGATTATGTAGAGATG GCAAATAGGTTCCTCTTGTATTCTAACTTTTATCAATTGGTAGTGGCTGATTATGGAACA TTTATGGGCTCAGCATAAAAAAAGTCATGATTGACTAGTGATGTCTGCCATGGGCAAGGA AATGGACTACAATGGCAAATTTCTCATATATCTGCCAGCTCTGCAGATCATTCATTTCAT GAGTCTGAAATGCCAAGGAACTGGTTTAGAAAGTTCTGGGAAAGGCAGAGATCTAGGTAT CTAAGGGTCCCAGAGAAAGAGGGGACAAGGAAGAGTTGAAAAGGGACCTAAGTATGCTTG ATCTGAGGGTGCAAATTAGGCAGCGAGACCTGCTTCAGAGCAGCAGCATGGGGGTGTGCA GCTGGCCTGAATTCCTTCAAGCAGTTGAGCATCTTGGCAGGATCCCTGCGCTGTGACACA AGTCCTCCCACCCTCCAGGTGCTTTTCCTGTATCCTGAGGTTGCCTTGCAGGCAGGAAAG GGGAGTGTGAAGGCAGTTTCATTTCCTCCTCTTCTCAGAGGAAGCCGCTACCTGGCTGAA CTGGGTGCCGAACACATGCTTTATCTCTCACCGTGTAGCTGCTGCCCTGGGCTCTCAGGG CCACAGAGATGTTGGCCGGGTTGGCTGGGAAAATGTTTGGGATGTGGAGGTGAAGACCCT GCAGGACATAGGTGGACTGCATCTGCCAAGAGAGACAGGGGTGAGGCTGGAACAGAAACG GCCATGCCCCCTCCCAACTCCTAGGTGGCATTCCTCAGCGCCGTACCACAGGACAGCTGG GCAGCTGTCCCCTCTCCCAGTCTCAGGGAGATAGTCACCTTCCCACCCTCCTTTCTCCTA GGTAGCTGGGCTGGGCAGGGAGCTTCCTGTGCTCTGCTCTCAGGCCTGTAGGCAGTGCGT GCAGCCTTATCCCAGAGCCCAGGCACAGCTGGTCTGACTAGTATTTGTGTCCCCAGGGCC CAGCACAGGGTAAGCATGGATAAATGTTTGCTGAAATGGGAAAGATAATGGCTGCCCCCA CAGGGAGTTCTCATCTGACACTGAAGCCAAGCTGAGTCCACAGGTTGACACAAGCACTGC ATAGACATGGACTTGCCAGAATGGCTCTGGACACAGCTGCAGGAGCAGGGCCCAGGGGCC ACCTCCAATACCACGCACTGCCCCTTTAGTTGCTATATAATGGAGTAGGATCCAGGAGAC TCCCACAGGAAGGGCTGGGGCAGGGGAGAGCATGTGGACTGCTCAGGGCAGCAGCCATTT ACCAACTGGTATGGAAGGAAGTCAGTATCTGATTGGTATGACTGAGAATCAGCCATGGAC ACCCTCCCACCACATGCCGCCATCTCATCATAGAAATACTGTGTGCCCCTAAGTAGCAGG CTGGGAGCTCCAACAAATGTTCCTGTGAAGGGGGTATGGAAGGCAATGACCTTATGGCCT GGGGGCTAGCATTAAGCTGCTGCCCACCCTCCTATCACACACACACACACACACACACAC ACACACACACACACACACACACACAAACACATCACTAACCTCCCCACTGAGGAGTAATAT GGTGAGTGGAAGACAATAGTTCTCAACTCTGAGTATCTGTATCATCTGAAAAGTTTCTTA AACTAGAAACTTCCCCAGCAATTCTGATTCAATAGCCTGTGGTTGGACTTGGAATCTGTT TTTAAAACAGCATATTTTTAAAAGCTCTGCCGGTGATTCTGAAGCACAGCCAGGCTGGGG AACCACTGTTGCAAAGTACTCACTTTTGTGAGCTTGCCCCTGACCTGCCTGCCGTGGGGC CTTGGGCAACTGACACACCCTCTCTAGGCCTCAGCTACCAAGTCGGACAATCTGAATGCA GCAGAGCTGGAAAAGCCTCTCGTTTAAGCCACCCATTGTACACATGAGGAAACAGGCCCA GAGAGATGAGGTGACTTATTCAAGGACCTAGCCTGGCACAAAGCCATCCCAGTAATTCAA CTCCCGCAGGAGGTATAGCAGGAGGAAGCTGTCTCCAGAGTTCCTCTTGCCGTACCACCG AGGGAGTTGGATTGCTGAGACGGCTTTGTGCCAGGCCCCATGCTAGCTGGTACGGGGCAG CACCTCACTTTATTCCCAGACTTTCCCCCTTTCCACATGCCCTGGGCCTCTGTGATGAGA AATGAGGCCATTCAGATGGTGAGTGGGGAGCCAGGCCCCCAGAGAAAAAGGGCAGGTATG CTCACCTGGAAGTAGACCATCCAGTAGGGCACCAGGGTCACCATGACGGGCAAGATCTTC ACCAGCACCTGGAAGTTGGCGATGTCCTCTTGCGGGGAAGCCCCTGGCTGGGGAGACCTC TCGTCGGCCAGCACGCGGGCACATTGACGGTCTCTGTGAGACCCCAGAGGCAGCAGATAA AACAACAGTCAAGGCTGGGCTTGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCT GAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAAGATGATGAAAC TCCGTCCCTACTAAAAATACAAAAATTAGCCAGGCTGTTTTGGCGTGCACCTGTAGTCCC AGTTATTTGGGAGGCTGAGACAGGAGAATTGCTTGAACCTGGGAGACGGATGTTGCAGTG AGCCAAGACTGTGCCACTGCACTTCAGCCTGGGCAACAGAGCCAGACTCCCTCTCAAAAA ACAAGCAAACAAACAAACGCAGCAGCCATAATCTTCCCCACCACCTCAGCCAACGTTTTC ACTTCTACCATCACCCCCTAATTTAATCCTCCTCCCAGTATCAGCACGTCTCTGAAATCA GTACCCTCATCTCCTCCACCCCGCTGTTAGCACCACCTTCGCCATCATCACCACCATCGC CAAGGCCAGCATCCTTACTATCATCACCTTTAGTAAGGTGACTGCTGTCAGCAAAATCGT CCTCTCCACGGGGTTTCCATTCACATCACCATCACTCTTTTTCAATGTTGGCACCACTAC TGCCAATATTATTCTATCCTCTCTTTTGCTGCAAAAGTGCCTAGCCAAGACTCATTCCGC TCTAGAGCTGTGGCCCCTCTGAGTCCTGAGGGAAGTAAGACCAGAGACTGTGGAAAACAG TCTGAAGGGATTTTTTGGCTCGTAGCATCAATTTGCCACGGGAACCAGGGGAGTCCCAGT CCAAGCCTGACTCAGAGAGAGACGCTGTCACAGATTTGATACACCAAAATTCCCCCCCCT TGCTGTCTCAAGTCCATCCTCCTCAACAGTCAACATGGCAACCCTCTCCCTCCATGACAA GGCATAGAGAGTGGAGAGGTGGGGGTAGAGGGAATATCAGTAGGCGACAAGATTGATCAA TCACTGCTGCAGCCTTTACCCTTTGCCCTTTGCCCTTTGTCCTGAGAGCTTTCTGACCTC TTTTTGTCCAAGAGCCTTGCACTGTCCTTTGAGATTCCAAAAGGGACAATATTAGTGTAG TCATCTCCAAAGACAGCCACTGTCAACTCCACCCTTCCCAGCGTGTGCTGCCATTTTGCC ACCAACAGGTGGAGTTTACTTTCACTGCCATTGTTTCCCTGCTGGCCTTGTGACAGCTTT GACCTGTTAGAATGAAGCAGAAGTGGTGGTCTGGGACTTCAACGCCTCTTAAGGACCTTA AGAAGACCCATAACTTCTGCTTTCTTCCTCCCCGGAACATTCATTCTTGGAAAGCTCCCT CCTCTTGGAACCCTCACACGACGCTGTGAGAAGTTCAAGCCACATGGTAAGACCACACGA ATGGGAACCAAGGTGCTCTGGTCCACACAGTCCCATCTGAGCTCACAGCCAACAGCCCAC ATTGACTGCCAGCCATGTAAGTGAGCAGACTCAGAAGTTCTAGCCCTTTCCAGGTCCCAA ATGACTGCAACCCCAGTGCCATCACGAGAAGCAGAACGGCCCGACTGAGCCCAGTCACTC AGAACTGGGAGAGGAGATAAAAAGGTCATTTAAATCACTAAGCTCTGGTGTGGTTTGTTA GGCAGCGATAGGTAATGAAAACCACCACACTTCTCGGCTCCTGACAACTTACAAACCTCT AGCAATATGCCAGACTGGGGAAAGCATGTTCTTCACCTTTTTCATTTAGATCCTATTGAC AGGAGCTGTAACTGGCTGCAAGGTCTGGAGACAGATTTGCTTGGCATAAGTAGACAGTTA ATTTAGGAAGGCGAGGGGCAAAAGGAAGCCATGGGACCTATGCAAGGTCATTCAGAACCT TCCTCCTTTGGATGTCAGCTAATGAGGAGGGAGCGAGTTTGGCCGATTTCCTAAGACGCT GTGATGGTTAGTAACAGGGTAATGTGGAATTATTTACATTGTATCCTAACAGCCTTCATT GGAAACATCATCCCCATCATCCTCTCCTTTAATGCCACTGTCATCCGCATTGCCAATGTT TGTGTCTTCAGTGTAGATACCAACACCATCATCCTTATCCTTACTACCATCTTCACTGTC AAGACCCTGATCATCCTCACACTTCCTTTTTTTTCATTTTTCTTTTTTTATTTTTTTCCT GTTCTGTCACCCAGGCTGGAGTGCAGTGGCACCATCATGGCTCACTCCAGCCTCAACCTC CTGGACTCGATTGATCCTTCTATGTCAGCCTCCCAAGTAGCTGAGACCACAGGCACAGGC CACCACACCCCACTAATTTTTGTATTTTTTTGTAGAGATGAGGTTTCACCATGTTGCCCA GGCTGGTCTCGAACTCCCAGGCTCAAGCAAGCCACCAGCTTCAGCCTCCCAAAGTGCTGG AATTAGAGGGATAGCCACCGCCCCCAGCCCCATCCTCACACATTCTGTACGTAGATGGCA ACCAATAATACCACCACCACTACCACCACTACCTTGACCTCCATCCTCAGTCACAGCGGG CAGCTCTGGCCCACTGGAGAGCAGATCATCATAAAAAGCTATCACTGTAGCTGAACCAGA ATGTCTGCAACCTGGACCATGCCTCCCCGGGAGCGATCCAGCGCTTCTCCAGGCTTGGAG GCTCCCTGCACCCAGAGCCCCTCCTTACCTGGCCGAGTGTCGTTGCCACAGCTGGGGGCA GCAGTTTTGGAGAGCGAGCTTAAGCATAGAGGACACTTGGCTGCCCATCGGGGGCTTGGT GATGAAGACGGGGGTGGCAAAGAGGAAGATGAAAAATGCCAGGCCCACACAGCCCACAGG GATGCTGTAGCCCAGCAGGAAGCTGATGTTCTGCTGAATAAACGCCACCACCAGCAGCGA CAGCACAGCACCCAGGTTGATGCTCCAGTAAAACCAGTTGAAGAAGCGGCGGGTGGCGTC GCGGCCGAGATCCATCACCTGCCATTCAGGAAGGGGTGACAGTGAGGGCCAAAGGGGTCC GGGGCACTCTCTGTACCCATACCCCTCCCTCCTACAGAGACACTTCTTGGGTCAGTGGGT GGTGGGCGTTCCGACACTTTCCCAGTCTCTGATCACAAACAGATGCTCAGTAAATATTTG CTGAGTGAATGAATGAATCCTTCTCTTGGGAGTCACTTGCTAAAGATCAGGACATTTGGC CCAGCTGCTTTTGCATACCCATGACACACACTGCTTTTTTATTGTCGCAGAGGAACACAT ACAACAGATGTCTCAGATGGACTTGTTCATTTCTGGTTGATTTATCCCTTTGTTTTTCAC TGAGCAACCTACACTATTCATTATTTTTTTTTTTTTGAGACAGTCTTGCTCTGTTGCCCA GGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCTTCCGGGTTCATGCC ATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCTGCCACCACACCTGGC TAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGAT CTCCTGACCTCGTGATCCGCTCGCCTCGGCCTCCCAAAGTTCTGGGATTACAGGCGTGAG CCATCGCGCCCGGCCTATTCATTACTTTTATAATCAGAAAAAAGCCAATAAGATCTCAGT TTTATTGCACATTATTAAAAATGTTGTATGCATGTTACCGAAAGAACAGAAGTCTGAGCG AGAATTTCCTCTGCAGTTCGGAGAGGCAAGCAGAGAAGCCTACTGTGACCCATCCTTTCA CCCCACTTTTGTCCCTCTGATATACAGCAGAGGTGGTCCCAGGCACAGCCCCAAGAGTGA GTTCTGGCCTGGTGAAAAAAACGTTTTTTTTCAGGCCTCCCAGCAAGGGCAGATGGGCTG AAAATCTTTACCCAGAATTTGGATCAATCAGCAACAGCCAGGCCCCAGGCCCCTTCTGGT CTGTTGGCTCCAGTCAGCTGCACTAGCTGCTTCCAAATCTCCCAGGCCCAGGTCCCAGAT TCTGACTCAGCAGGTCTGGGGCAGGACCTGGGCATCTGCATTTAAAAAAAAAGCAGTGAG GACTAGGGGCCATTTCAATGGAGAGAATAAATACTTCTCTACATTGCTAAACCAGTCACC CTTTCCATGCCCCTGCAAATCTCAGGATCCATTACTGCCTTTCAAGTAGAGATTTATATT TCCACTAGCTAGGGCGATTTTGTCAAACTTTACTTTCTGTAGTTGCATTGGGGAAAAGAC AAGTATTTATTTTTCCTTTTTCAAATGTAAAATTATAGTCCACACAGATGCACTTAAACC CGCATTCCATTGGAGATTCTGCGGGGTCCTCCTGGAAGTGGGGAGGGAGGGGCATACCAG CTCACTGATAATTCTCGCTCTAGACTTTCAAGCAGAAAATTGAATAGGTCCCATTAGAAG CAGCCACTTCCATTTATTAATTGGAAGTAAATGAATGTGACTATTGTAACTCTAAGGGGG AAGACCAGGCAGCCCATTCAGGATATAAATGAGTTCTTTTAGAATGAGCAGATGCTTTGT CGAGAGTGATGGATGGCCCTTTCTGAAATCAGCAAGTATGTGAAACACGCAGCTCCTGGG GTATAGCTGTTGCCAGATGGTGCCAGTCCCACCCACCCCCACATCCCCATCTGACTGCCC CCCTGAATTCTGCAGCCGCTTCCTGCCTGTTGTGAAGTACCCACTCTTGTTAACCCATAT GCTATCTACACTGCAGCCGGAGCCATTTTTGAAGAGCTCAAATCCAGTGATGTCCATTCC TGCCTCAAATCATTTTGGTGTTTCTGCACTGTCCTAGGGATCAGGTCCCGACTTCATGAG GCCTTGTGGCCTGCCTTTGCTCCACCCAAAGTTCGTGCCCAGCCAAGGGGAGAACGTACA GGAGCTTCTGGCCCTGTTGATGCCACGGGAGGCTCTGCTCAGTGGCCTGGCCTCCAGAAG ATCAGTTTTGCCACAGGGGGTACTAGATGGGTGAGGCTCTCTGGAGGTCAATAGGGTCAA TGACACAGGTTAAGGGTACTGGGTTGGGGGTGCTAGTGGGATGTCAATGAAATAATAGGA TTAAAGGAAGATGAGAGATTCCCATTGACAAATATTGGGGGTCTCTAGGTCAGAAAGAAT GTCAACAAGAAGTAAGAAACGGTCAGGGCTGGCCGGTCGCAGTGGCTCACGCCTGTAATC CCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTCAAGACCAGCCT GGCCAACATGGCGAAACCACATCTCTCCTAAAAAAATACAAAAACTAGCCAGCGTGGTAG CGGGCACCTATAATCCCAGCTACTTGGGAGGCTGAGGCAGGGAGAATTGCTTGAGCCCGG GAGGTGGAGGTTGCAGTGATCTGAGATCGCACCTCTGCACTCCAGCGTAGGCAACAGAGC GAGACTCCGTCAAAAGAAAGGAAGAAAGAAAGGAAAGAAGGAAAGAAAGAGAAAGAAAGA GAGAGAGAGAAAGAGAAAGAAAGGAAGAAAGAAAGAAAGAAGGAAAGAAAGAAAGAAAGA AAGAAAGAGAAAGAAAGAGAGAGAGAGAAAGAGAAAGAAAGGAAGAAAGAAAGAAAGAAG GAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAA GAAAGAAAAGAGATGGCCAGGGCTGGCCTGGGGGCATGAAGTCATCATCAAAGGATCCTA AACAAGCTGGACAAGTGACTCCTTGTCAAGGACACTGGAAACTGCTAGGTGCTGAATTGT GGGTGCCAATTGGATGAAACGATCCTTTTGAAAAATGTCCCCTTTATGAGTATAATATGT GCAATCAAAGAACATTTGATAAACTGAGACAAGAAGAAAGTGCAATTAGTCCAGTGGCCT GATCATACCACTGTGACAATCTTTTTCCAGTTTCCTTTCGTTGACACCTCGTCTTTCCAC ATGGCTGCAGTCCTATCTGTATGCAGTCCTGCCTCCTGCTTTTGCTCATTTACACCATAT GTGGTTATTTTAATAATATTACATTTTAGTCTAAATTATTGTCTAATATCCCACTGGGAA CAGCTATCAAAATATAGCCGTGTTGTTGGGCATTTACTCATTCATTTAGCAAATACTTAT TAAATTTCTTCTACGTGCCATGCTCTGTTCAAGGGGGAACGGAGAAAGGCTCAGAGGTTG AGCTAAGGGAGAAGACCAGGCAGCCCATTCAGGATATAAATGAGTTCTTGCCCATGTGGC TCCAGCTAGTGAAAGGCAGAGCTGGGATCTGAGCAAGTCGGCCTGACAGCCTCTAGCACT GCTGGTAGGAAGAAGCTGGCTTGCTCCTGCCCTGCCCGCACATCCCCATAACACACAGAG AGGAGGTTCATGGTGGGACCTGGAGTCCAGCTGCCTTTACTCGGCTCCTCGACCCTCCAT GTCACCTTGGGCAAGTTGATTAATGCCATGAAACCTCTCAGTGTCTTTCTCTGTAAAATG GGCATAATAATTCCTACTTCCTGGGTGGTGAAGAGTATTAAATCAGTTAAACAGTGAAAG TGCTTAGCATAGGGCCTGCAAGTAGCTCAAAAAAGACCAACCTGCCTGGCGTGGTGGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGCCTAGGCAGGTGGATCACCTGAGGTCAGGAGT TCAAGACCAACATGGTGAAACCCCACCTCTACTTAAAAAAAAAAAAAAATTACAAAAATT AGTTGGGCGTGGTGGCAGGCCCCTGTAATCCCAGCTACTCTGGAGGCTAAGGAGGGATAA TCGCTTGAACCCGGGAGGCTGAGGTTGCAGTGCGCTGAGATCGCGCCATTGCACTGCAGC CTGGGCGACAGAGTGAAACTCCGTCTCAAAAAATAAAACAAACAAAAAAACAACCATGGT TATTCCCACTGCGGTTGCCATCGGTTTTGCAAGGGCTAGCCCCCCTCTTCTTTCAAATCA GGAAACTAGTGCAGGCAGGGGACCTGGTTTGTCCCAGGTCACGCTGGGGGCCAGCCCTCC TTCCCTCCACACCCGCCGGAGTATGCCGGGGCAGGCCTCCTGCCACTCACCTGGTCGGCA CCGAAGGAGGTGAGGTTGCTCCGGACGGAGCTGGCGGCCAGGCCGAGTAGCAGCAGGCCC GCGTAGAGGACGGGCGCGCAGTAGGGGCTGGGCGAGGAGCGCGGGCAGCCGGCCGAGGGG CAGGCAGGTCCCAGCGGCGACGCGGGCATCTCTCCGCAGAAGGAGCTGCGGCCGTCGGGG AAGGCGGTGGCGGGCAGCAGGCCCGAGGCGGCCAGGTAGAGCAGCAGGCTGAGCGCGACC GCGCGGTAGCGGCCCAGGTACACGTCGGCCAGCCAGCCGCCCACGGGCGCCAGCAGGTAG GAGGCGCCCAGGAATACCAGCGCGGCGCGCGTCGCCTGCTCGCCGGTCCAGTTGAAGTTG GTGCTGTTGAGGTACAGCACGAGGTTGGCGGTGACGCCGAAGAAGGCGGCGCGCTCCAGC ATCTCCACCAGCAGCACGGCCGCGCCCGCCGCCCGCCGCCACCGTCGAGGGCCCCGCGCA CCGCGAGGCAGCAGCGGCTGGCGCTCCCCGGGCACGCGGGGCTGCTCCCGGGCGCGCGGC GCGGGCATCCTGGCTCCGGGCTGGGCCCCCCGCGGCTCTTCTCTCCTCTCCTCTCCCCGC CTCAGAGCCCTGCACTCCTGCCCCCGGGCCTCGGCCCTCTCCCCCACCCAACTGGCTGGC CCTCCTTTCTCACCGCTTTGGCCCACCCTTCCCTCCTGTCCCCTCTCCCTTTCTTGCCCT ACCCTTCCTGTCCCTCCGCTCACTACCCGGACTCTACCACCTCCTCCCTAATTCTCAACT CCCCTCTCCCTTCCCCCACCCCTAAGGCTTCCTCCCCGCGCCTCTCCTGCAGCTGTTTCT CCCTAACTCTCCCCTCTCCTCCCTCCACCTTGACCCTTCCTCGCACTCTTGTTCACACTG CGACCCTCCCTGCTTCACTTCGCTGCCCCTCCGCCTCCCTTTCCCCTCCCCGTTTGTCGC CCCTTCCTGTTGTCCCCTCTCCTTATGACTCCTGGCCTGCCCTGGGCGTGGGGTGGGGGC TCCCTCTGCCCCAGTCACCCTGCTGCCCCTTGCCGTCTTCTCCACCTCCTCCCTGTCCCC CTCACCCCCACTGCCTACACTCCCCTCTCAGTCCCCTGCAGCCCTCCCCCCAGGCTCAGC CTCTGTCCCTCTCTCGGCTTCTTGAGAAACTCTGGGCTCCCCTCGCTTCCCCTTTCACAG GCCCTATCCGCAGTCCCCTGCCTGCATCACATGGCGCTACTGGGTGTTTAGGAGAAGTGA AAGCCTGGGTCACAGGGCTCCTGCCCGGTCAGCTTTCTAAAAACCTCCCTCCTTCTCTAC CTCTGCCTCCTACCCCAAACCCCCGCTGCTGGCCTCCTTAGAGCCAAAAAATTCCAGGAG GAATTTTTTCTTTCAGTTTCATTTCTCGCCAGGATTCCACTTTTGCTTTACCCTCTTCCA ATCAAACTCCACGCCTCCACCCGAGGCGCCACGGGTAGAAAGAAGTGGAAAGGCTACCTG CATCATTTGGTCACACTCAGCCATTTC bcftools-1.21/test/csq/ENST00000536784/ENST00000536784.fa.fai000066400000000000000000000000221467060157400215530ustar00rootroot0000000000000011 15447 25 60 61 bcftools-1.21/test/csq/ENST00000536784/ENST00000536784.gff000066400000000000000000000025731467060157400212060ustar00rootroot0000000000000011 ensembl_havana gene 1 15447 . - . ID=gene:ENSG00000110446;Name=SLC15A3;biotype=protein_coding;description=solute carrier family 15 (oligopeptide transporter)%2C member 3 [Source:HGNC Symbol%3BAcc:18068];gene_id=ENSG00000110446;logic_name=ensembl_havana_gene;version=5 11 ensembl_havana transcript 1 901 . - . ID=transcript:ENST00000536784;Parent=gene:ENSG00000110446;Name=SLC15A3-007;biotype=protein_coding;havana_transcript=OTTHUMT00000396444;havana_version=1;transcript_id=ENST00000536784;version=1 11 havana exon 1 290 . - . Parent=transcript:ENST00000536784;Name=ENSE00003535089;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003535089;rank=3;version=1 11 havana three_prime_UTR 1 290 . - . Parent=transcript:ENST00000536784 11 havana three_prime_UTR 433 466 . - . Parent=transcript:ENST00000536784 11 havana exon 433 483 . - . Parent=transcript:ENST00000536784;Name=ENSE00002225178;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002225178;rank=2;version=1 11 havana CDS 467 483 . - 2 ID=CDS:ENSP00000441694;Parent=transcript:ENST00000536784;protein_id=ENSP00000441694 11 havana exon 787 901 . - . Parent=transcript:ENST00000536784;Name=ENSE00002265924;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00002265924;rank=1;version=1 11 havana CDS 787 901 . - 0 ID=CDS:ENSP00000441694;Parent=transcript:ENST00000536784;protein_id=ENSP00000441694 bcftools-1.21/test/csq/ENST00000536784/not-a-start-lost.txt000066400000000000000000000002151467060157400225500ustar00rootroot00000000000000899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G 899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G bcftools-1.21/test/csq/ENST00000536784/not-a-start-lost.txt-l000066400000000000000000000002151467060157400230010ustar00rootroot00000000000000899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G 899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G bcftools-1.21/test/csq/ENST00000536784/not-a-start-lost.vcf000066400000000000000000000005411467060157400225110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 11 899 . A G . . EXP=synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G;type=ENST00000536784:60705454-A-G:incomplete 5'cds bcftools-1.21/test/csq/ENST00000542803/000077500000000000000000000000001467060157400166465ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000542803/ENST00000542803.fa000066400000000000000000012520221467060157400210010ustar00rootroot00000000000000>1 1:107682629-108026080 GAGGTACACGAGGAGTTACTGGAAACGGCGCTTCTGTGGAGGAGCCGGGGGGGATGGGGA GTAGAGGGAGGGGGCCCTGTTGCCTCAGCGCCCCGAGGTCGTGGAGCGGCAGCAGCTGCA GCCGGAGCAGCACCAGCAACAGCAACAGCGAGCGGGACGGAGTTAGGACCGCTCGGAGCG CACAGGTCTCGAGGTAGTATAAGGTTTGCTATCCTTCCACTTGCTGGCAGTTGCAGAAGA AGATCTGCTTTTTAAGTGAAACGTACATGCCACCCCTCCGAGGGCTGCGGCTTCCCCGGG CTTGCTTCTTTGCCGCTCCTCTTTCCGGCTCTCGCGCTCACTCTTTAATTGGCACTGGCC CCTAAGTTTGCCAGGAGCTCGCTGCCCGCTCGGAGCAGGGTCCCGGCCGGGAGCCGCTGG TGGGGGCGGGGAGTCCGGGAGCCGCAATCCAGAAGCGTCGTGGGCCATGTATATTTCATC AAACGGACTTTGGGTGCGTCGCGTCTCACTGCCATCAGTGCTATGTGCAGTGACATTTCT GACTTGAGTGGAGGAATGCGCGAAGGAAACCCGGGCGAAATTGGTATTAGAGGATCTTCT TGGCGCCAATGCTAATTGTCCTGATTTATGCCCCTTCTGACTAAGCTCAACGTCTTCATC TGAAATAAAATGAAAGCGGTGCCAAGCGGCATAGAACCGCCTGGCCGCTGGTTCTGATCC CCGGGAACCAGAAAATCGTCCTGCGGCTTGAAAAAAAAAAAAAGAGGAAAAAAAAAAGAA ATAGAAATAGAAAAAAGAAAAAATATCCCTCAGTAAAAGTTTAAGGCGAGAAGTGTCAGA GGCAGCGGAGCGAGGAGGCGCGGAGGAGAGCCGGCGAGCAGGGGACTGGGCTGGCACGAC CTCCGAAGGCTGAGATCTCATTATTAATATCACTATATTTTTGGAGGGAGAGGCACCTTT CTCATCCTCTCTTCCTCTCCGCCCACCCTTACTCCCTCCCCCTCATCTACCTGTCAAAGT CACTGATCTTTTGCATTTCGGAAGAGGACGTCAACGGGAAGGAATTCCCCCTCTGGGTGC GGGCTCCGAGAGGGGGCGACTTGCAGGAGGCTCCCCCCGGGGGCGGAGGCGAAGGTAATT AAGCGGCGGGGAGTGGCGGGCCGGCGCTGGGTTCTCGGTCCTCGGGGTCCTCTCCCGCCG GCGGCCGGGCGCGATCGGAATCCCCGGGCTGCGGCGGTGGCGGCGGCTCGGGTCCTCACG CCCACCCCTCCCGCTCCGCCCGCTCCCGCCTGGGGAGGAGGCTCCGCGGGAGCTGCCGCC CTCCGCCCGTACGCCGCCCGCGGGCTCCGCTGCTGCGGCCGCCGCCCGAGGCGGACCAGG CTGGCTGCGCAGGGCCGCCGCCCCGCGCCGTCGGCTCGGCTCCCGCCCGGCGCAAGGGCA AACGAGCCACACGGTAAGTGCCTGCGGCTCGCCTCTCCTACTGCGACCCGAGCCTCTCGC CCGTGCCCCTCTCCCCCGGGTTTCCCCACCCCCCGCCGCCCCCCGCCCCACCCGCTGCGA TGCACAGGCGGGAGGGAAGGCTCCGGGTGGGCGAGGAACTTTGTAAAGCGCCCCGAGGAG GCAGCGCGCGGAGCCCTACGCGCACACACAGCGGCACACGCTCACACCCACACACAAGTC TTCCCGGGGGTGCGCCCCGGGCCGGTGATGCGTCCTCTTGTTGTGTCCGGAGCCCAGGCG TGGGGTCTGAGCCTCCATCCGCCGACTGACAGGGGCCCCGCGCTCTCCCTCTCTCACGCA CACCTGGCCACACACATCGCTCAGGCGGCTTGTCGTTATTTTTTCTTTCTTTCGCCAATT ATATTTGTTTGGGGAAAAGCAAACAAAAAAAACAAAAAAACACTTGCCCTATTGCCGGCC TTGGGGATCTGGTGGCCACATCGAGAGCTTTTGAAGTCCCTTCTTTTAATCGCCTTTATT GGTGCTAGATTAAAACATTACTATCCCATGTTGTGCAGCTGGGGAGAAAGGGAAATTGAA AGAGGAAGACTTGGTGTAGGGATGCTGTTTGGAATATTCTCTCATATTCTTTACTGGCAT CATATTAATCGGTTGATGGATTCGGCTAGGGACACTGAATTGCACTCCTGTATGGATCTG TGGATATCTATATATAATACAAATAATACTGAATATTATTGGGCCTAAAATAACCAATTA AGTGATTCATACAAGGAAAAACTTAGATATAAAAAGAAACTGCGCCCTCTGCTGTTAATT TTAGTACCCTCACCCGGGGACTTTTTTTTTTTTTCCTTCAGAAATCCACTTAAGAGTAGG CTGTCATCTTACAGGGCAAGGGAAGAAAATTCCTAGCGGGGATTTTAAAGCAACTTTACT TGGAAAAGTCGCAGGTTGAGCTCCTATAGTTGCATCAGGTACAGATTTCCAGTGAGTAGA CGGTCCTCCTCTCTCACCCATTCTTCTCTTTATACAGGGAATAATGGAGCCACTCCTCAT AACAAATTGTCAATCTTTGGAATGGAAAATTCTGAGTAAGATTCAGAACTCCACTAAACA TATGGTGAATCTGGCAGTAGAATTGCTCTAGAAATAAGGCCCTGTTTTATGACTGAAAAT ACTAAAAGTTGTTTTATCTTACAGAAATGAAAAAAAAAAAAACCCAGGAAGATCTTCCAT TAAAATCACTTATTCAGATATGCTTAGTAGTTAAGCTTGTTGGAAAGTTTTCCAAAAAAT AATTTTTTTTTTTTTCAGGGGAGGCTTTTCTGTTTTGTTTGTCCCTTGAGGAGGATCTCT AGTGAGGGAATTAGCAATTCCACATTTCATTAAGTATTTTGAACTGTGTCACTTTGAATG CCTTACCCGCCTCCCTTTCTCTTTGGCAAAGGAAAAGCAGCTCAGTAACTGTCCAAGATT CTTTTTGAAGATAAGCAACTTTCGATTTTTCATTAAGATAAAATTTGGATCTCTGCATGT GGATCAACATGCAAGGAAAAATGTGCATCAAGTATTTCACATGTAATGTTGTTCCAGGGA TATATTTTCTTTTCTGGATGCCGTGAAATGAGATATATTTCACCCACTGAAGACCACCAT GAAGGCATTCAGGATTCTATATACTGCACTACTAATTTGGTGGTATTTCCTTACTGTGGA ATTTAAGACGGATAATCTTAAAACTTTTGCATGGAAACAGTTTATTTGAACATAAAGCTG GTTTCCTGTTAATATTTTTGTTTTGTCAGTTTTCAATGGGTATATGTGTTAAAATGATTC AGGTTAGCCTTTTTAGGAGGAGGCAAATGTATTTTGCAGTTTCCTTTTGTATATTTGCAA GTGGTGCAAATACCTATTTTTGCTTCCATTATTATTCTGAAAAATATTCAGGTAATTTGT TTAAAAAGTTAAACCATTACACATTTATTTGATAGGATTTCTAAGTGTCATAAAAATTTG GAGAGTTTTAGTTACAAAGGCATCAAGTCACTTGGAAAAAAGAAAATTGGATTCAACTTT GAAAACCAATTATATGTTAACATTGAAATATATGTGTGTGAATTATATTGTATAGGAGAT TATATTAGTAAAGTCTTAGGTTAGTATGAGATTTAGCATACTTTAAAAAATAATTTTATT TGCAGAATCCAAAGTTCTGTTTCAAAACTTCAGGTAGGTGTAGATTTTCTCATATATGCG TTTGAGACCTTAGATCTCTGAACTTCCCTGCATGAGAATTAAATATTTGTTTTTCATGTG GTAATTAAATTCCAGATTTCTTCTAGGCTTAACTGATTCTGAAATAGTTTTGGGTATTAT CCCATCCTCAATCATCCTGCAAAACATGTGCTATCTAATTTCTTGAATCAGTCTTCTCTC AATGAAAATAGAGATCTTTCAATTACCACGGTGTGTTATTTGGGTTTATTAAGAATCTCA TGATAGACAGTTGCTCATAATACCCAATCAAGTGTGAGTAAGCTATGCCAATGATGTTGC AGTACATATTAAATTCCTTATATTTTGAGAGACAGTTAACAAAAGGATAGAAGCATATGT TTTCCATTAAGTTGACTAGAAAATGCTTTCTTCAGAACAAATAGCTGCAAAGAGCATTGA ATACATGTTAAAATATCTTATGTAATAAATTTCATTATGACTGTTGGAAGCTGCTAATTT TGATAGGTTATAATTTTGTATATCTTTATCTTTTTATATTTTCACTCAATGATCTATATA GTCAATTTTCCTTTTGTTCCTTCCCATTCAGAAACATGCATATTTATAAAATTCTTAATG TGAATGAGGAATGAGTCAATAGTTGTGTATTTCAGGTACCCCTGAAAAGCTGAATATTTA TGAAAAAAATAGCTTACTACCACCATTCCCACCTGCTAGTGAGATTATATAATAAAATGA ATGCTGAAAACCAGCTAGATTAGGAGATTTACTGATAATGTCTTCCTCTCAGTTGATGAA ACTGGCAATTGCTTTTGGAATATAATTGCCTGTAATATTAACCATTATTACTTCCATGTA ATATTTTGGGAGGCTTTTTTTTTCTGGTGAAAGAAAGGGCCTGTGAAAATGGCTTCTGCA AAATTAATCCAAGGTGGAAGGGAATTAGCTGCAGAATCCTGGACAAATACATGTTTTGTG TGTGCAAAGGCATTTTATAGCCCATTTTAGTCCTGATCAATAATCTCTATCAACTTGAGG GCCATGACTTAATTTTACCTTTTATTATTGGTTCTGCAAATTTATACACCGGAGGTCTAT GGGGTACTCACAACCTATTAATGGGTATTTTTATCAAAGGAGACTTCTCAGTACTTTAGT TCCCAAGTAGAGGTGGTAGCATTTTTGATTACAGTGAGTTCCCAAGGTCTGCAAAGTGAA GAGGTAGAACTGGAGCTGCCCAGAGCTCTTATGAATCTGTTCTTATTTAGGTGATACGGA CACCTGAGACAAATTTAAAGGCCACGTCACTTCACAATTAGTTCAGTTATGGGCCAGAAG GGATAGGTTTAGTATATTAAGTCCCCAAATATGTTATTCACTGTCCTTCTCATAATTGGT TTCCCTAGCTATTTGCTGTGATGACCTAGCTTTTAAGAAGCTATTGATAATTTTAACCTG TTTGAAAGCACAGCAGATAGACACAGTGCCATTAAATAGTGGAGGTTAAGTTGTAAATAA TATTCTATTTTTACATCATTGTATTTTCTTTGAAAACTCTGTAATTATACTTTAATAACA AATTCCTGATTTTCAGAGGCTGCTTTTCCATTGTGTGTCATGGAAGTTCATAGATTTAAT TTCTTACTAATTTGAAGTTAAGAGGATTTCCTTTGAAGTATATGTGACACTGAAAAGTAA GAAGACCCTGAAATGCAGGATACATAACAATAGTACAAATATAAAAATTAGAATGAAATC AAATAATTATGTTAAATAACAGCTTAGTGTCCCTCTGCTCCTGATCTGTAATACGCCGTG GTCAATATCTTTTTCTGTGTCAATGGGAGCTCATTAAATGTAAACTCTGCAGACTAACTG AGCCATGCCATATTAGTGCTTGCCAAAGCTTGACATTTTTAATACATTAATAATATGTCT GTAATGTAATGGAAAACTATTAATCACAACTGGTTATGTGCCAGAAATTTAAGCTATAAT TGGCTGCCTCTTGTCAAGAATGTCTGTTGCACAGTCCTGCAACTGCCTAATATTCAAATA TCTTGCACTCTTCTGCATTTTTCCTTGTCAGTTCTCTAAATTCGATCAATGGTGTAGTCC ATAATTCTGTGTAATGACCATCATTATAATCCTGGTATACTTTAATGAGAATTCGTTATA TTGGGATTGCTGTTGTGTCAGGAGATAGCAAAGGGTTCACATATATTTCCTTAGTGTTCA AATTTTTCCTGTACAAATGTATGGTCACCCTTTATTTTGTGGTTGCAGTAATGCAAAATG TGGTTGAGGACAGAGTAACCGAGAATAAATGGATGAGGAGAATATCATTTGTTGGTTAAA AAAGAAAGTGAAGACTAATCTCAGGAAGCACTCAAATATATTTAAAGTGGTATTTTCAAA CTAATATTAAAAATAAACACACAATGCTCACTCCATTCAAACTCAAAACAGTCAATTCCG GGTCTTCAAGATTATATCATTCTTGATAAATAAATTACTGTGTATTTGAAACTAAGAATT AAAGTTAATAATTTCTGACCTAATAGATTTTACACTGCTTCAGTTATAATGCCTCCATCC CCCGGCCCTTTGGAAAGTATTTGTTTCCTCTTATAAAAACTAGTAAACACAGTTGAAAAA TTCATCTCAAAAATGTAAATTTGTATCATTTTAACACCTCAGATTATTAATTGTCAAATT GTTGGATGTGTCTGAAAATATCAACTTAAAATTACTAATGAATCTGAAAAAAAGCAGAAG GCTATAGTAGCCACAACACATGCTTCTCTGATTTTTTTCTTTTTAGCTTAAGATTTCAAA ATGGGCTTTACCCAGTATAGTTTTTAGGTTACAAGGAAGAGGCTGATTCAAATCTGTAGT TTATACATATTTAGACAAACTACTAATTATTGCTTCATAGGAACTCAAATATTCAACACT TTTTCTATTAGAAAATATCACAAATTGCAGCTGTATGATAACATTTTATGAATTGAATAT AATGAAAATTGCACTTGCATCCATAAAGCAATTATTATAAATTACTTTGCTATGGAAACA CAATTCAACCATCTGTTGGCATTTCATAGTCTCTGTGGCTTAGTTCATTTTAAGATGGTA CATTATTTAAATATAATGAATTCCCTTTATAAGATTGTTTGAAGATAGTGAACTTCCATA TTTCAACTGTTTAATGTGAATTGAAGGGTCTATAATAGAATTTTCTAAAATTGTAGGCTT TTTTGTCCTTTTTGCATTGCTTAAAAATCAGTTAACTTTTAGACTATAAATATAAGCAAT CTAATTAAGAAATTATACTTTTTAATACCTGGTTTCCAAATGTTAGCATTTGTTCAGATT TGGATAGTGATCTCTAAACAGAAAAGTGGCCAGTTAAACTCACCAATGACTTGTAGCCAT AGTTATGTAGGATGCATTATCAGTTAATCAAAAGTACTTTTACACAGTAATTTTTATTTT CTCTTAGAATTAGTGCCATATTATTCTGCTTCATGGCCTGTTAACTCACCCTCGGCTATT TTTATGTGTGCATTTTAAATTGTGCGTTTTACTACAGAGCTTTTAGTTTTAAAGCAGCTT ATAATATTCGCCTTTGGGACAAATTCTCTTCTGTTACAAAAAGTAACGGCAAATGCAGAT GTAATGGCTATAAAAAGATGTAAAAATATAGAAAATTCTTATGAAAGGAAATTTTGCTCC TTTGGTTTTATTTTTGATTTTTTTTTTTCAGAGAGCCAACTTATCTTTATTACTAAATGC AACTAAACAAAAGATGCTAAATTCTTCCAATGTAATGAGCAAATCCACAGGGACAGGCTT ATGCCAACAATGCGGATTTTCACTCCAGCAAAGAAAAGCTAAGAAAAGTACAAGGAATTT GGAGATTTTTAGGGTCTCTTTGCCAAGAGACAAAAGGGATATAAGTAGTTGTCATTTCTT TGTCATCATTATAAAAGTGCTCATTTACCCCATTGTTCTCTTGGAAGATTTTCTAGCACT GCAATGTATGAGAAATGTTCAAATCTAGCTGCTTGCTCTCAGTTTTGTCAAGATGGAAAT ATAATTTTTGAAGTGAAAACCTGTAACTCACGCACACGTGTCTGTCTTTGTTATGGAAGA GTTAAATCCTTCATATTAAAATTCTCCCCAATGTGAATGATTTCCATGGTTTGCTCATTC TAGCAAAGCAGCTGAGTAAAGGTTATCTGTATTACACCAATTTGCTTTATATTGCATCAG ACCTCCAAAATGTCAACATATTGTACATTTCGTAATATATTGATTCTGGGACAATAACAC TTACTCTTATTGTTTCTAAAAGGGTGTTGGTGCCAGAAGAAAAGAATGATTGATGGGAAA CAGACACCGGGCTATAGACACTCATCCTTTTGCTTCAGATACTGATATCTCAGCCTGCTT GAGCATCCCTTGTGAGCTGTGAACATTGAGGATCACTCAGGGTTATCGGATGTACAACGG GAGAGCCATCGCTTTGCTAAATTATTATCTGCAATTGGACATCTTTTACAAAAACCAAAC TAGACCTGAGTCTAATAGATATGTTCTAAGACAAAGAAAAAGCTGCAAGTTGTTAACGCC TAACACACAAGTATGTTAGGCTTCCACCAAAGTCCTCAATATACCTGAATACGCACAATA TCTTAACTCTTCATATTTGGTTTTGGGATCTGCTTTGAGGTCCCATCTTCATTTAAAAAA AAATACAGAGACCTACCTACCCGTACGCATACATACATATGTGTATATATATGTAAACTA GACAAAGATCGCAGATCATAAAGCAAGCTCTGCTTTAGTTTCCAAGAAGATTACAAAGAA TTTAGAGATGTATTTGTCAAGATTCCTGTCGATTCATGCCCTTTGGGTTACGGTGTCCTC AGTGATGCAGCCCTACCCTTTGGTTTGGGGACATTATGATTTGTGTAAGACTCAGATTTA CACGGAAGAAGGGAAAGTTTGGGATTACATGGCCTGCCAGCCGGAATCCACGGACATGAC AAAATATCTGAAAGTGAAACTCGATCCTCCGGATATTACCTGTGGAGACCCTCCTGAGAC GTTCTGTGCAATGGTGAGGTAACCCTTTTGCATAAAATATTTCATATAAATAGGGTCTAA TCGCATATGCATACAGATGTGGTGAGTGTGAAGACAATTCATGCAATAAGTTGAATCTGC AGGTGGCAGATTTGTGTTAACAGGCTAGTTTCTTTCTCAGTGGAGGCTTACACTGCCTGG AGTTACAATTTGTGCAGGGTGATTGATGCCCTGGAAGGAACTTACTTTCCGCTTCCCTGA AAACCTATAGTTTCACTGAGGCAGGTACACTATAGCATATATTATAAAAGAAAAAGTTCG ATTGAAAGTTAAATTTTAGATTGGAGGTTGGAAATATGATTAGGTCATATCTGTCATGTT AAGGATAAAATGCATTGGCAAACCAACTTTAAAAACACAAATGTTTCTTCACATATGTGT ATAAAGCCAGTCCTAAATTCTGTAGTTCAAGGAGAGACTAGATCTCATAATTATGTTCAT CAGGAAGCTGCTATGATTTGGGAGTCCTTGGTTAGGAGATCAGCAAGAAAAAAAGTAGAG GAGAGAGGAACTAAAGCCTTGTGAGAAGTTTTTCCAGAAAAATCTTATTTGCCAACTCCC CTTATTGTCAAGGTCATAGTTTTCTATGTATATTTTAAAGATGACTTTTGGAATATAGAA AACTTATTTGCTGAAAAGCAAGGACTCAGCATATACAAATTCAGATACTTTTTTTTGATG AGCAAAGTTACAGAATTCATTGTTCTGAAGGCTTATATAAGTCCTTTTTTTTCTGCATAG AAAGTTAAATACCATGTGAAAAGGTAATATTGGAGTAACACATTGAATTTTTAAGAAAGA CATGGCTGACAATATTTCTATAAGTATTAGTAAAGAGGCTGGTGATTAAAATAGTATACA TTAATGTGCTAAAGAGTTCAGATGGTGAGTTCATTTGGTTTTTTTTTTAATTATAGGTGG TTTTTATTTGATAGAAGAACTGCGATCCTGTTTTTCTCCACATAACAGATATAATTGTAT GGCAGATTTTAATAATAATCTTACCTGACTATATTATCTTGAACCTGGCCTGGCATTTTC AGGATAGTGAAACTATTAATCAAAGTAGCATCTGTTCACAGTCCCCAGTGAGTTAAATTA GCATAAGATCATCTTAGACCTAGCACCATAAAAAAGGTTTTGTAACAGGAAACAATTTTG AGCAATAAAGAGTGTTTTCACCTTAAAGCTAAGGGCTTGCCATTTTTCAGAAGTGCCTTT GGGGACTGGTTTGAATTATAGTCTAAACCTGATTTTGTGGAGAGTGAGAAAAAGCACTTG GCTATTAGGTGTCACTGTTACTAAAGTGCCCTGAAAGACTAAATATTTCAAAGAGAGGAC CCGTCTCTATGGGAACAGGTATGTGCTTTGCAAAGAAGTTGCATTTTGGAAAGCAGAGAG TTCCAGAGAAGGAGTTTATTCAAACACATTAGCAAAATCATAATAAATCAGTACAGGAGC AGAGACATTTGTGGTGGCTTTATGTGAGGTCTTTAATAATTTCTCATGAAAGGTCAACTA TAAGAGCTCATTACAAATCTGGGTTGAAATTGCTGTTTGGGTGATAGGTTGTATAGTCTT CTACGCCTTATAGCAGAGGATGAGTTCCAGGCCAAGTCTGCATATTGTTAAGAACTCTCT AGCTCTGTATATTGGTTTACATGACACTTGTAACAACATGTCCCTTCTGGAATTGTTTAA TAATTTACAGATCTAAGTAAAATAGCAAATTTCCTTTCTCAGGGTGCTGTTTTCCCTCTC ATAAGCCCTGTGTGATGTTTTCAAGGTGTGATTTGTGGGTGCAGCTTCCCTGATCTCAGT CTCTGGCCAGAGAATGCTTGCTTAGCACTGCTCCTGTCTGTCATGTTGAAGGGTTTACTT GGTGTCTTCAGCATGCCTCTTCCTCCCATCATGAGTGCAAAGGGCATGTTACGGATCTTC CCATGCCTGCCTTTCAAAGGGACATGGTCTAAGGTATTTAAACAAGTCCATTCCTCTCAG TCCATTGGCTAAGTGATGTTAGAGACCAAATGGGAAAAAAGAATTAAAATGATATCCCTC AGCTTTCTCAAGTGCAGTAATGTGTATACTATGTATGTTCACATGAAACTCCGTAGGACA GTCTTTAAAAGGCTGCATCTTAGTGTGATGCGGATATTTGGAAGCCCTGGTGGATGTAAA CTTGTCATTGGACAGAATGGTTTTCCAAGGGAGAATGTAAGATTTGTGAAATATTACCTA TCAATGCTTAATTTGTATTCCTTAATATGCATATGATAGGCATAACAAATTTAATAATCT ATCCTTTAAATATATACCTTGTGACTATTTGTATGCATATTATATACCACGTCAATGGTA ATGGCCTAATACAGCAACACATTCACTCTGCAGTTTTGGATGTTCCATAAAACTCTTTAG CATAAGGATTCCTGACAGAAGGTTGGGAAACTGTCTCAGGATGCTGTCATATCAAACCTG TTTAGGTACTCCTTAGCCCAGGGTGTAATGGGGATTCATAAAGTCATTTGTGTTATGACT TATGCGTTCTCCCCTCCTTGACGCTTGCATCCATACCTGCTCCCTCAGAGTCATTATGGC CTATTACATCAGGGGAGCTGCCACATGAGTACAGCCACTGCTTAGCCCCTATATGTAAAT GTTTGCTGCAAAATTGTTTCAGTAATCACTTGTTCAGCTAGTGACACTCCTATTAGCTGT GGCTATAGCTGTTCTGAGCATCGAGGGAACATGTGCTGAGAGAAATACCTATAATTCCCA GGGCCAATTTCTTTAATATAAAGTTGAAGTTCATTGGCATTGCATTAAGAGTCCGTGTTG CTGCTTTTTTCATTGACTTCATCATTATAGGCCAGTGACTATCCATGAATGTTGCATTTA TTTTAATATAGAGTAAAATTTCAGGAAAAGAAGGAGCATATGGATTCCATTTAACAATAG ATCTCTGCTTATTAACCTGGATGGCATACTTAATAAATCTTCAATGTGAAGTACTTTAAA ATTGTTCTATATTAATTGTACCAGTATTTATAAACATTAGTTTTTCAGGAGCACACTGCC ATTTCTATTAATCATAGTGGATAAGGAAGAGGAATATATATATATGCACACACATATATA TATACACACACATACATATATATATACATACATATATACATACATATATACACATATATA CATACATATATACATGTATATACACATACATATATATAAATTGCATATATTGAAAACCAT ATATTTTCTTTTTAATTTGATATATTCCTTTTGAGTTGATGATGGCTAAAGAAAATCTCT GTTTTTGTCAATGGGGAAGAATCTGAAGGGAAGGTGGGGGTTAACCCTTTTTTTAGGCTG GGAAAACACATTTGAATAGATCCTATCTTTTCAGCCACATTGAAAGCTTCAGGTGGCAGA GCTTTGTCAGGAAACACAGATCATCTAGTGACTACAATTTGTTTCAATTTGCATAAAGAG CAGAGAGGATGATCTGAACCTGTGTGTAAAGCTGAAGTGACAACACAAAGCTATGACTTT TTCTTTGTGTTTAGACAAACTTAGCTGTCATATCTTCCCGCACACCCCAGTGGCTTAAAA ATGGCAAAATTATCTGCAGTTATCTCTAGCCTGCAGCTAATTTTCTGGATAAGTTAAACA GACGCTTTGAAAAGGAGCCTACAGACGGAAGAACTCATGTGTGTTTATACAATTTATGGC TCAGAAGTGCTGATCACTGTAGAAATGGAAGCCCTTGAGTGCTGCTATGGATTTCAGAGC CAATCAAAACTAAATTAGGAAACAAAGATTATTAAAAAGTCTTCTGTGCATGTAATTTTG GCATAATATTATGAGGTGGACATTAAATGTTTCCCTTGGAGACGTTCAGCATCATTAATG CAGCATGCCTTTAATTACAAGTAGACTCATATTACTAAAAAATTGGAGAAAATAAAGTAC TCTGAGGTACAGTTAGCAATAACCTCATTATGTTTACTGAAATAATTAAAAGAAAAGGTA TAATTTTTCTAAATAAAATGTCAGAATGTGAAATGAAAATGGATTTTACTTAGGAAATTT ACTAATGTGTGCCTGTGCTCTCGATAGGCATTTATTCAAGTACCTTAACAGATCTATTAA TGATCACTCCATATTGTGCTATTTCTAGATAGACTTCTATTATGAAAGAAACTTTAATTA TTGTAAGCATTGTGGATAGAGCATATTTCATTATGTTCAAATGGAATTTACGGAAGTGGT ACAAAGCCTTTGTGTTTTGTGGTTTCAAAGGAACGCTGAGAGATGAGTGACTGGTAACTC ATAATCTCAGGGCTATCTATAATTTCAAGTTCTGATTTACCTTTGGCTCAGGTTGCCATC TGGTGGCTGTCAGGTGACCCTTGAGAAAAGAACTTGATAAATTCAGTTACATTTTCCATG ACATGGAATTACTATCAATTTTCCAAAAACTGGAAATGACATTGATTTATATAATAATCA AATAATCTTAAAAATACACTCTGTTCACATGAAACATAATTCAGTAAATGAATGAAGTTT TAGTAACAGTGACACCTTTCATTTGAACTGATTTATCCCTTAATTATGCCAAAATGGAAT TTTTAAAAACCTTCAGTTCTTTCATTATTAACACTTCATTGTTATTAGTTCATTATTTAG ACTTATTTCTTAGAAAAGTTTAACTCATGTTTGGAATGAATTAAGTTCCAAGGAAGTCTT TCTCATATACCACTATATCAAGTATTTCCTTTTTGAGGAGCCTACAATAGCTCCTTACTA TCTATTGCATCATGTCTAAATTACTCTACCTGTTTTTTGAATTTGGGTGCATACAGCCTA TCGTCCACTACTTCTCATCAGGACTCTATAGCATCTCCAGGGGACTATGGCTGGCAATCT GATTGGAAGGGGACAACTGGATTTGAGTTGAAACTGCCTTGGCATAGCATGCATGGCTTG TTGGAGAGGTCTTAGGAAGGAGCTGATGAAGATTATGGCAAATGTAACAAAACCTAAAAC CACCTCATGTCATTTATTGTCCCAGATAGTGTGCGTAAGTGCTCTTTGTTGAGCTAATGC CTCACAAACATTACTGCAAACCATTGTTTGCAGAGTGAAGTGAACAGAGCATTCAGCACA TGCAAAACCTAGTGGTGGTGGAGATAACTAATGTCGAATAATATATGGTCATTGCGGCCA ACAGAAGTAGAGTCCTGAGCAAACTTAATACAAAGTAGTGTGTATACAGAGGGTAGAAGA ATAGAGAAATAAGACCAGCACTCAGAATTTAAAGGTGAAATATTATTTTGCAACATGTCA AAGGCCACTTGGAAAATACTATCTGGTAGCCAAATGCCAGAAAAGGAGAGAAAATATTAA ACAGTGCCAGAAAGGGAGAGAAAATAAGGCTGGGTTGGCCAAGTACAGTGGCTGATACCT GTAATCCCAGCACTTTGAGAGGCTGAAATGGGTGGATCTCTTGAGCCTAGGAGTTCAAGA CCAGCCTGGGCAACAGAAAGAAACCCCATCTCTATAAAAATTAGCCAGACAAGGTGACAT GCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCTGTTGAGCCCAGGAGG TCAAGGCTGCAGTGAGCCAAGATCATGCCACTGCACAACAGCCTAGGCAACAAAGCAAGA CCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTGGGTGGAGCAGATGGTGGCA CAGTGTTTTAATGACTGCCTGGTGTCCTGGTTAATGGTAGACTTCTTCTTCTATCTGGCA GATATAGCCAGGATGGAAGAGGAACAAAATAATAAAGAACCTGATATATATATATATATC AGGTTGGAATATATATATGTATATATATTTCAAATATGCATATATAGTTATTAATTTAAG AGATACCAGACTATGTTGAGTAAAACAAATGTGGCTTATCTACCTGGAACTCCAATTTCA CGTTAAGATTAGGGGAAAGATTTAACCGAATGCAGAGATGCAACATTTTTAAAGGTGAAA CATGAGACCTCAAAATAATGAATGCTTTGCAGTGGAATACTGAAGTTACCTCCTTCAGTC CCCCTGGAGATAACCTTGTCTGCTTTTAATCTAGAGGATCATCACTTGCAAAGTGTGAGA AGCATTGCCCTAAAGCATCAGTCTCTCTGGACTGTTTTGAACTATAATGAGCATATTCTC CAGAATTTTGGAAGGCTTGCTCTGCTTTTCTTTGATTTTTGTTTTGTTTTGTTTTGTGTT TAACATGGGCTTTAGGATGGTCTCTTGATCCTCTGATTTTGAGGACTAGTGTTATCACCA TGAAGCCCTCGTGTCATCTCTTGTCTCTAGGAGGACAAGCAGAAGACATTTCTTCTGTTT GGCATAGTCCGTGCTCTTCTCCACTTACTCTGATGCCACCTATCTTTCAATGTCTAGCTC AAGTTAATTTCAGGTCATATCATTCTCTTGACTTTTTAACTCATGTTAAATCTCTCTCTC TCTCTATCTCTATCTCTCTATCTAATATGTATAGATCTCTATATCTAGATAGACATATAT AGTAGCCAGCACTGCCTGTGTACTCAACTGTACTCCACCATTTAGCACCTCATTAGATCT TATTGATTTATATACCCACATACACATTCGCTTCATGTTTACTGTATTCTGACTCTTTAA GTGGGTCACTACTCTTTAAGTGGGATGATATGTGAGAGAGCCACCACACTTGCTAATGTA TAGTAGGAATTCACTAAAGACTATATATTATATTGTTTTTTATTCCTTGAACATACTCCA AGGCAGCAAATAAATGATAACATGGTTCTAGCTAATTAATTGATTTGAATATTTTAAAGT CATGCACTACATAATGATGTTTTGGTAAATGAGGGACTATTTATACTACAGAGGTCTCAT GAGATTAAAATGCTGTATTTTTACGTACTTTTTCTATGTTTAGATAGATTTAGGTTCACA AATACTTAACATCATGTTATAGTTTCCTATAGTATTCAGTATAGTGACATGCTATACAGG CTTGTAGCCTAGGAGCAATAGACTATACCATACAGCCTAGGTATGTGTAGCAGGGTATAC CATCTAGATGTGTGTAAGTACACTCTATGATGTTCACATAACAACAAGATCACCTAATGA CACATTTCTCAAAATGTATCCCTGTCGTAAAGTGACACGTGACTGTATTTGATTACCGTA ATGTTTTCTATTTCTTGAGCACATTTATCATAAATCTAATGTTTTCCTCTGTAAATTAAG AGACAACTAGCAAAATTTAGCTACTGTACTTGGGCAGCTTATGCTGCTCTCAGAAAAGAA ATTGTAGAGGCAAAATCTACTCTGAACTCAGATACTGAAATCTCTCTCTTTTTCTGTAGA CTATATATGAGAATTTTTTTCTATTTCTAATTAAATATAGGAGGTTTGGTATGTGAGGAA ATAAGAATCTGTTTAGATAAAAAAGGCTATCCTGATATATGTTCAACACAGCATTATAAC CAACGGAAAAAAGAATGAAAATATCATCAAGATATCCAAGTGGAAGGCAATTAAATAAAA TATTGTATAGCCACATAATAGAATATGTATAGCTATTAAAGTAATATTTCTGAAGAATAT ATAATGAGAAAAATAAACATGGAAAACATAGTAGTAAATTTGTTTAAAGAATGATATGGC AAAATGATTTCAATGTTGTGTATGTTTTTAGGATGTTGAGCTCATTGTATTGTATTTAAT TGAGGCTAAAAATTTAGGGCTGCATTCCTGTGTGGTCCAGGGACAGAACTGCCATTGAAT GTATACTCCGTGTCAGTCATGGGGAAAGAGGTGTCAGGGAACTTAGGCAGGTCCCACTCT CTGGTCATTGCTCTCTTTTGTCTGTGCTTCTGGAGGAAGAAGGAAGGTAGCCTTGACCAC ATGGTATTAAGCGAAGTCAGGCCATCTCTTTGGAAGCAATAAGCTGAAGATGAGTAAATT ACACCTTGTAAACTATACCTGTGGCTTTAAAATTTGCTTTAAATCGATCCACAGTGAGAA ATAGATTTTATGTTGGAACACAGTAAACACACACTTATCCCCACACACGGCCAAAACAAA AGCTTCACAAAACAGAGCTTACACTTTCTATGTGTTATGGCCTCTGATATTTTTTCTTCC ATTATATTCTTTTCTCTTATTTAACAACTAATTGGAAAGTATATACTGATTATGATCCAC AAATTATATGTAGCATTGTTTTTGAAACTCGAATAAGTGGAAAAATACTGTACCAAACAT TGCATAATGTCCTTTTTTAAATTGAACATGAAGTTTTTGAGATAAACTGTTGTATAGTAT TCTAGCATATGAATATCTCTTCAGCCAGCCTTCTATTCCTAGGCATTTCAGTTTTTTGGA TTTTACACTCTAAGGTTCTTGATTGGTGTTGTCAAATTGTCCACCAGAAAGATAGAGAAA GATAGTTAACAATTTGTACTTCTACCAGCATGTTATGCAAATATGCTAGTCATTATCCTC ATCAATACTGCACATTATATTCTCACATTTTCTTACACTAAAAGGCCTTAGCAAATAAAT GAGGATATGGAGTTTAACCAAAAGAATAATGACAAAATTATCTTATTCCCACCATCTGTT TTCCTAAGGTTATAATGTTTTAAATTTGAGATTGATATAGGGACATATTTGAAGGTAAAA ATGGCATTTCATTTTTTTTAAAGATGCATTTATTGAGAGGGTTGATTTTTAATATGTTTC TTGGCTATTTAAATTTCTTTATTTCTAACTGTAAGAGTTTTAACTCCTTTGTACTTTTTG CCTCTTGGATTCTAACTTTTTACTAAAGCCAAAAATTAATACTTATTTATATATATGTAA TATTTGGACCTTTTACAAAAACTCCATTTTCTGTCAGCATAATCCATTCAAAATATGAAT ATCTTTTTGCCATAGAACAGATATCATTTCAGAGACTTTTCCACACTCCTCATTTTGTGG AAATGTTATGGATTTCTGCACTGGATTTTGGTGGTAGAGACATAATCTTAGGGCTGGGAA AGATTCATCTGAGTGCCTGCTTCTGTCTTTTGTTCCTATTATAAGAACTTGGCTAAGTTG TCATTTACTCTCAGGCAAAGCATCCTTTCCCCTTAGAATCAGTCCCTTTGAAAAAAGTTG AATCCTAAAACATAATTCCTTGTATAAAACTGCTGGTATGAAATCTGCTCTGGTTTTAAT TCACCAGTCTAATTGGCAGGCTGGTTTTTTGTGTGCCATTTAAAAATTTCAGAGTTTCTT TTCTTACAAAAGGGGAAAATGATGAAATTTGTTTCATAAGCATAAGATTGGAAAAAACTT ACTGAGATCGGCAGGTTGTAAATTTCTTTTCACCTTGCTAGGAATAGATAGATTCATATA GTATCTATTCCATGAAAATTAAAGATGTGAGCTGAGGAAAAAACAGAATTGGTTTCTCTT TGACCTGCTTTGAAGCTGACTTCTAAAATATTAAATGAAGAATTGAACTAAGTGTTGCTC CAGTACAAAGAAATAGCCCTTTTGTTTCAGAGAGTTGATGTCCATTGAGAAGTCCAGCTG CCGACATTATCATGAGGCCATATCTGCACAGTGATTTTTCACCGTCATATGTGGCATTTT GTTGCTTTCCTGTTGCTCCCTTTCCTTCTTGGAAATTGTAAAATGAAGAAATCAAGTACA CTTCCAGACAATTTCTAAGCGTGGTCTGGAAACTTGTCTTGTGTTTCAGCAATGTTGTCA TGGTTCCTCTATAGTGATTCGTATGAAGGAAAAAATTATAAACTGGTAGAAAAGATTAGA CAAGTGTAAGGAATATGAAGCCTGCCGAGAAGTTAAAAGACTGTTCTAGAAAAAGAATTC TATATTTCAAAGAAAGATATTTTAGTGTGTGCATAGGTGCCAGAAGACATGAATGTGGGA TGTGTAAAACTATAAATTGTCTGCCAGATATGGAGAGCTGAGATTTGTAGGTCATATGAA GGTTATACTAAAGGGCCTCAATCTTTTTGAAAATGACATTCAAAATTTTTGGATTCCTTT GTGGGTCAGAGTAGACTGAGGTCATTCATATTGTGGACCGTCTGCATGCTCTCTCAAGAG AGAACAGAATCCAATGTGTGTGGTCTGCATAACTTACAGAAGAAGATGTGTGCATGACAT AGAGAAAATGAGTTGGTGGCCAATATGCTAATCTGAGGTTGGTTGTTGATGCCTGGGCCA CTCCATATGGGTTTTTATTTCAAAGTTTAGAAAGACTAATCTTATATGAGGTGTTAGGGA GCATACTCATCAATGTGGCTACTATCTGGCTCAGAATCATGTTCTATTTAGCCATCACGG GAGACAGTGCTTTTATAGTGCCGAGCATGGTGTGATGCATATAGGAGTAGTTACATGCTT GTTGAATTGAACTTTGTGCTATATTTTTACAGATAATACTTGTAGCTGATATTTATGAAG AACTTACATGGTGTCATGCACTGTACTGAAAGCTTGGACTGTGTTGGTTCTTATAATCCT CAGTCCTATCTTATCCTTACTCACCAGAGTAATTGGAGCCTGAGGTTAAATAATTATTCT AAGTAAGTAGTGCAAACAGGATATAAACCCACTCTGACATCTACGTTCCACTCTTAAACT ATTCTATTCCTCCCCTAATTTTATTTGCAGCATATGGAATAAGACCATAGTGAAAACCTT TTTTAAAAAATCAAATTTTTGATTTGGGCTGTGAGCTACAATACTATCATTTTGTTATTT AAAAAGCCTTTCATCTGAAATAACCTCAGAAAATTGGATTGTGTAAACAGAGTGTATGGA AGGTTGAAAATACATATTACGTGATGAGTGTCTTCATTCAGGGATAAGAGAACTGATCAA CAGTGTTTGTTTCCATTCTTGCTTTCTTTTCCATTAACGTGTTCATATAAATGGAAATAA GCTGTTAGAAATCATAGAGAGCGGAGTACATATTGTATTCATCATGTAAAAAACAGAATA ATAAGTCAGCAACTGTTGGCTAGTTAACAAAATCATATTCTTGTGGGTGAGGTGTTGAGA AAAGTAGTTAGTGTGATGCTTTTGTTTTGTTTTTGGTTTTTTACAGTATCAATAACAACT GTTATCATATAGCCAACTGCCTACATGCTGTCTCTACTTGGATGTCTAGTAGGCAGTTTA AACTTAATGTGTTTATTATAGAACTCTTGATTTCTTCTTCCTAAATCTATTCTGCCTCTA GTATTTCCCATATCTGTAAATGGCAACTTATATTCATCTAGCTGCTGAAGATGAAAAATC TAAGAATCCTCCTTAACTCCTTTATATCCCTCACAACATATATTAGCAAGTGCTGTTAGC AAAATCGTCAAGATATATTGCAAATCCAACCACTTTTTACCTTCTCCACTGCCAACAGCC AGGTCTCAACCAGCTGTGTCTCTAGGCTAGACTCCCGCAGTATCTCCTAATTGGTCTCCC TGCTTCCTACTTTTGTCCTACTATCAACATCATTTATATACTATATAATATAAGCTATTA TAAAATAGAGACGTACGTAACATAATAATGTATGTGTGTGTATAATTTAAAAAAATCTCA GCCAGTCTGACCCTTTCCTTGTTCATTTTTTCTCGTAACTTTGTGTCCATTCAACATCAT ATGCTAACCCTTACTACTGCCTGGAACTTCCTATCTAATCTGGCTCCTGCATGCCTCTCT AACCTCCACTGTCATTGCTCCCACCTTGCTCAGTCCTCTCTAGCTGCACCCTTTTGCTGT TCCTTGTAACACTGTTTATTCCTGCTTCTTTGCTTGGATCTGCATTCTCAATATCTTCCT ATAGTTTTTTCCTAACTTTTATTCAGGTCTCCACTTAAAAAACCTCAAAGGGGCCTACCT GACCACCCTATTGAAATGCATCCTCTGAATTTTTTATGGGGATTATAGTAAAAATATTTA CAAACCGGGACAGCACAAATACTGACCAATCAGAAGAGATGACAATGGTTTTACTCCTTA CAGGCCACTTTCTGACTATCAGACTATAACTGATATCTCATAGGTTATATATTTGCTCAT TTATTTATATCTCTTTTCCCCTCCAGAATACAAGCTCCAAAGGGTAGGAACTGTGTTTCG TAGTGCCCATAGTAGAGCCCCATAAACATTTGTTAAATGAATGAATGAACCGTTAAACAG AGATATATTTGTTTGACCATAACCTTCATATCAAAGATTATTGCTCTGATATACACAAGG TCTTTGGGGTATTGGCTGTGCTGGAGGCCCTTAATCTCTTAAAGGTCCTTAACCTTTAGC TTTATTTTTCAATTAAAAATATTTTAAGGTACATAAGCAGTATAATAAATACACGTGCAA CCACAACTTATAGGCCGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCT GAGGCAGGAGGATTACTTGAGGTCAGGAGTTTGAGACCAACCTGGCCAACATGGCAAAAC CCCATCTCTACTAAAAATACAAAAATTGGCCAGGTGTAATGGTGTGCACCTGTAATTCCA GCCACTTGGGAGGCTGAGGTACGAGAATCACTTGAACCCAAGGGGCAGTGGTTGCAGTGA GTTGAGATCGTGCCACTGCACGCCAGCCTGGGTGACAGAGTGAAACTGTGTCTCAAAAAA AAAAAAAGAAAAAAAGAAAAAACACCAAAAAAACCTCCACGACTTATGATTAACAGTGGT AATGTTATATTGTTTTTGTTAGAATTAAAAAAAAAAAGATATCACTGACAGAGTTGAAAT AATCTTTGTCCCTATTTCCCTAAGAAGAAATCAGTATCTTGCATTGCTGTATTTCCTTCT AGTCCATGCTTTTATGCTTTTATACATGGATTATGTGTTCAAAAATAACACATACTTTTG ATTTTGGATTTTTTTAATGTTACCATCCTGGAGAAAAAAAAAACTATTCTGTAACTTGCT TTGTCATTCAATGTTATATTTGTAAATTATCCATTTGATCTATATGATCATGTTAATACT ATATATATGTACATATGTATGCATATGTATATATTTTATTGTATAAATACATAACTCATT AATGGAAATTTAGGAAGTTTCTTTTTTTATTTTTAGTTTTTGCAATTACAAGCCACTCTA CAAGAAATATCCTTGCACCAAACTCTTGGTGTGTATGAGCAAGTTTTATTTTGTTTTTCC CAAGGAATGCACCCCAAAGACAATCTGTTGGACTGTAGAGTATGAACATTTTCGTCAAAT GGGGATGCACTACTTTGAACTCCTATCGACAGATTTTAAGTATTCTCCTTAATAAGTTTT GTCGTGTTTATTGATATGCTTCCTCTTATTATGTAATTACTATATTAAGAAATCATGTTT CTCTTATTTTCTTAGCTGTCAGGAATAGATTTTATGATGTATCATGGTAACCACAATTAA CTTAGAATTTTTGGTAAAACTCTATGTACTATGCCTCTTAATGTCTCATTTTTGTTTTAA TTATTTAATAATAAATCACTTGGAAGTTGCATAAGCATCACCAATAAATATTTAGAATGG CAAAATAACAGAAAGAAGCATGAAATTTGGATAAATAAACATTGAGCTAAATTATGAGCA AATTTCTTTGACTAGAACTTTACACAGGGGGCAACAAATTTTAAGAGTGGCACCTTACAT CTGGCCACCCGAATTAAAAGATATACTCTGACCTATACAATTTGTATAAAAGTCCTTCTT TTAAAATTTTTAATACTTAACCATATGTAATTTTTTTCCCAAATTTACCGTCTTCATTAC TAGACTATAACAATAGCCTTATAGTGCTTTAAAACTGGAAGTCTTTTTGCTTACTTTGCA AGATGATATATAAATATTGCATCATCCATCACTGGAATAACTTGTCTCCTAGATTAAAAC CTGAGGGTGATGTGTAACTGTAATAAATTTGGACAGCAAGGAAGGGTTCTATTTCCAATT AAAACCACAGCCAGGAAGTTTACATTTAGACTGACAAGGGAGGTAGATCAGTACACATTT TGTACATCTTCTTGTTTGTTCAGGGGGAATTGGAGGATCTTTTAAAAGTAGCAATGATAA GTCTTTACATTTCTTTATGACCTCATAAAAAAGAGTCAATTGTCCCTTCTTGAAAGGAAG TTTCTGGGATCAGAAGCTTTTTGGGTTTTTAGACATTTAGAGCCAAGTGTTCTGAAGTGC CATGTCTAACATGGGGAAGTGCATACCTTTATGGATATTTTATTTGGATTTAAACAGGTC TGAAGGTTCAAGATGTACCTCAGTCAAGTTATTTTACTTCTTTGTTTTGAAAAATAATAA GATGATGTACTTAGCACAGGGCCTGGCATATAGTAAATACTCAATAAATATTAATTATCT TTATCATTGTGATTATCATTTCTCTTGCTAAAATGTACAAGTCCTTCTGATGCTTATTTT CTGCTTTGAATGAATCTTCTGAAGGTTTTCCTATTAGTTTCCCTTTCTGAAATGTGTCTG GCTTTCCTGGATGTTACTAATGGCAGCTAGTAGCTAACTGCTTGTGAGGTTCAGGCTCCA AGTAAGGTATTTAAAATCAAAATAATTTCACAACTGTGATTTTAAATTAAACGAAGTGTA TTCTAAATAACACAGAATTAAAATAATCACTCATGGATACAATGACATTTGCACTGAGAT TATATTGGCTCGGTGTTTTAACAACTGCTTTAGAAATGTCTACGAACGATGTAATAACTA TTTCTGAAAACAAAGAAAGCTAACAACATAAACAATTGTGCAAATAAATTAAAGCTCTTT TTATTAATGACATATTGGAATAGGCTCAATATGTTGGCTCTCATAAAGGCATAGCAAGTG AGAGGAATTCCTGCTGCATGGGAAATGGAAATGCTAGGTTCTAAATCAATTATTTTGGCT GCCATATTATCCATATTATCCCCTTCCTCAAAAGCATCCAATGGATTTCCGTCACACTGC TACTCAACAAAACAAAACATTATTAGATGGAAACTTAGCTCCATAATTTCTACTTACTCC AGTTGCATTTTTTACTTCACAGTGTGTTCAATTAGAGACAGCAACAAGTTGCATTATCAA GGTGACTGTGAATTAAAAAGAGGTGCTATTTCCTTCCAATACATGTAGCTTTGTACTGTG GCTTGAGGAGGGGAGAGCAGGCTGGATCTCAGCCTCCACCTCTAGCTTGGTTGGACTTCC TTGTGCTGGTCACAGCCTGGCCAACAGTGCCTGCTGGTCCCAAGCACCATGCAGGCCTCA CAATTATAACTTGATTTTGTGCAGGACTCATACTACATTCTGGAAAGAGAACCATGAAGG GTGAAAAAGCTGTTGTAATCCATACAGAAACTTTATTGATGTGACCATTGGGTGATAAAA GTAACAAGTGTTAGTAATTTAACTTACTGAGTACCTGTTATGTGCAAGGTACTGAGCTAG AGGTACAAAAATGTGCAAAACAGACTTATTTCCTAACCTCTTGGAGCTCATAGCGAAAGC AGAGAGAAATACTTAAATAAGTACACCAGTAACTACTACTGTGATAAACACTTCAAAGAA GAAATTTAAGCTCCTATGAGAGTATGTAATCTTAATGCTGGTGATGTCAGGAAAGTAAAG ACCATTGTTCTTGAGGAAAATATGAACGTTGTCAAATGCTAGATTTGTGCAGTAATGGTT TTGGTTTTGCATCTACATTTTTACAGCTGTTAGAAACAAAACGCTTGTTCCTCAGTGCCA CAAAGAAATAGCACTCAAACATAAATTTAATTTTCTCAGCAAGGCAATTTTTACTTCTAT AGAAGGGTGCAACTTGCGACTGAATAATGGCGAGAGCATACCTAGACAAGGGAGGGGAAG GGGTTCTTATTCCTGACGCTGTGTGGTTCCCCTGTTGGCTAGGGTTGGACCGCACAGTCT AAGCTAATTCCGATTGGCTATTTTAAAGAGAGCAGGGATACGAGCCAGAGTGGGGTGAGT AGTTTGGCGGGAAGGGCGGTTACAGAACAGGTGACTCAGGATGATTCAGGTCAGAGAAGG TGACCAGGAGTGACTCAGGATGGAGCAAGTGACCAGGGGTGACTCAGGTCAAAGCAGGTG ACCAAGGGAACAGATGTGAACTACTGATTAGAACTAGCGGGAAAGCTGTTTACTGAAACT AGAGGCAAGGGGCGAAGAGAACCAGGAAGTTAAACTTTAAAATGGAGAATCAAAGAATAA GAGAGCTGAACATACTGACATACGGATTCTTTGAAGAGAAACTTGGAATTCACTATATCT AACAGCGTTTAAGACATGCAACTTTATTATTAAAATTCCTACATTAAAATAGCTTTGCTG TTATAAGACGAAAAATCCCTAACTCCTTTTTGTCACTGAAACTATGTTTTTAAGTTAATT AAAGAGCAAGTTTTCTTAGCAATGCAACTGCCCTCTTGTAGTAGGTAATTCTCCTTAACA ATGCACTCACCATTTCATTTTGTAATTATTAGTTACTAGTCTGCCCCCCACATCAGATTG TAAGCTCCTTGCAGACAGAAATGAACCTGTGTTCTCTATTGTATCCCTGGCAATTAAGTA TAGTGCCTGATACATAGTGAGCCCTTAATATCTAAGCATGGAATGAAGAATCCTTCTACC CTGTCTGCTTTCCTAAATTTCTGCTCTCCACTTTCACTCTTTCATTTTAATTATTGTCCG TCAATAATCTTTTCTGCCACATTTTTCTTATTTCCAGTGACTTTGCCATTATTTATTATG TCAAAGTAACCTCATGAAGAATCTGGCAGAAGGTGATACTTGGGGCTGTTTTGTGGGAGT ATTTAGTGGTTTCTCTCCACTGTGAAGTCCCTACGTTGTGTTCCCTAAGTGTTCTCTAAA CAGTTAGTTTAGTGCTGCATGTATTTATGAAATTCCTTGCTCTGTAGAGCCCTGGGCTGG GCATAATGGGAGATAACAATGACAGACTGGCCTCTGCCTTCAAGAAGCTTTATAAAGTCA ATAATTATTTACAAAGAAGAAACAAATATTATGCCAGCACTACATGTAAATAGCAATGGG AACACAGAAAGAAGCAGTTCATTGCAAACTCAGAGGGATCAATGATAGCTTCATAAAACC AGAAGGCCTTTGAGCTAAGCTTTGAGAAAAAAGTAGACTACTCTAAGCTGGAAGAAGAAA TAGAAGGACATTCTAGCTTAAGGAAACTGCAAAGTCTTGTATTTCGCTTTCCTTTTAAAA TAAGTTTCTTTTGTAGATTTATCTCAACAGTAACAAATGTTACCATTGTGCTGTCTGTGA ATTAATGTAAATCCTGCTCAGCTCTCCTTGTGTTTCCCAATACATAATATACTACCATCG TTTCTTATACTTCGCTTCATCTCTCTATAAGCAATCTTTAAATGCAATAATGTAGGTGAA GGTACTTTATAAAATGCACAGTACTAGATAAAATAGGAGGAAAGTGGTATACAAAAGTAA GTTGCCATAATTCTTATTTTGTATTTATTTGCAAGCTCAGTGATCACAAATCATAAGTAC TTAACAGATAATATAAAGATCCAATTCAAAATATATTTACAAAAGCCTGATCAAGTAATT TTGGACAAGTCACTTATTCAAACTTTCTGGGTTTCAGGGAGTTTTTAATTTTTTTTTTAT GAAGATTATCTGAAACAATTGACTGTGAAACCAAAAGTACAAGAAAAAGTCACTCTTAAT AACATACCAGACCCTTGGATTGACCCTGGCCTTTGCCTATCAAAAACGTTCTAGAGATAT GAGACTTACATAATGGAGATATACAATATCTACATAACAGTAGATGGGGAAATATCAAAG TCACTGGTGCTGTCATTAAGTACCATGGGTTTAAGTGCTTTTATTTAGAGATGGGTACAG TCAGAAGGATCACAATGACACAGAGTTCAGATACAAGCAACTTAACCTGCTCTAGGTCGT AATCTCTGACATTCAGAGGACATTCTGTAATCCCAGCCCAAACCTCAGTTTTCCCTCCAA TTCTCAAATACTGATTCATGACTATATGACAGTTTCAGTGGTATATTGGACTGTTGGTTT TACCACTGTTTTCCAGTAAGAAAGATTTATAAAATTGCCTAAGTTCTATTTTATTTGATT TGCCCCTCAGTGTTACAGAACAGATCTTCATAACTTCATGAGACTGTCTACAGTTATCCT TAGAGTGGCACGAATTTATGCATGTTCACCGAGAAGAACTTTATTTTAGAAGAATCTATC TGTAATGACAGAACATCGGCATTACCTTTTCCACAGTTTATTAGTAGTGGGGATAATATA TATTCTATATGATTTATTATTATCAGTGTTAAAATTTCGAAAGTGCCTAAAGTTCAAGAC CCATATTTATTATACTAATAACTTGTATAATTATTAGTACAAATATAAAAATAATATGTA TTTTTATATTTGTATAAAAACTTAAATATGGTTTTATGTATCTTTAGTCATGTTAATTCT AATATGTAGGTAAAAGCCTCATTTAAAAAATGAGGAAACTGAGGTGAAGAGGTTAAATGA CTTGCCATAAGTCACAGTAACTAATAAAAAATAGTTGTGAGATTGCTGGATATCATTAAG GTGATAATAATTAATTTTTATTGAGTATATTTCATCAGGCACTGTCTTAAATGCCTAACA TGTATTAATATAATATTTGAATGAAAGCGTGAGTAGATTTTAGAAAGATGTAAGTATATT GCCCTTAAGTTTTCCAGTTTTTGTAAAGCCATTCTTTTTTTTTCATGTGTATATTGTTTG TTAGTTAAGTAAGCATTTGGAAAACAAAACAAAACTTTACAGTCATAATTGATGCTTCTT ACCTTGGGTTGTCATAAGGCTTATGAAAGGCTCTGCAGAAATAATGCTAGAACAGACTCC TCTGGGCACTACAGGATGGAAGGCATTGGGCTATTGACAAATTGATACCAGAAGAGAACT TTGAGGTCTCTGAAGGAAAAACACCCTGTAATTTCACAGTATAACTAAAGGGAGCTTTAC TTTGAAACAAGATTATTCATGAAGTCTAGCCTGAAATGAACAAGACAATAAGTGTTGCTC TACTGCCCTCCCTCCCCGCATCCCCCTTATTTCCTTCCTTCCTTCTTTCTCTTTTTCTTT TTTAAGGAAGTACATCATCAGCACAGGAAATCACTGGTAAAGTCCTCATTTTCACTTTAG AATCCTGTCAAAAAATGACCTTAGCAACTAGATTGTAATAAAAATAATTTCAGGAAGCTG TAAAATTATGTCTACAATTAGTTATTAATCGATGAAGTAAGACACTACATCTAGAAGAGT ATTTTTCTGATATATAAATCTTATTTGTTTTTAATATTCTGGACAGTTTAAAATATTTCT CTCTCTCAGTAGAAACTTTTCCATATCTGCTTTAACTTGACACTATGCCCCTGTCTACAA CTGTTCATGAGCATCTCTGCTCCCTTGAGGAAAATAGAAGTGGAACTACTTTGTGGTGAC ATTTACCAAGGACAACAAAATAAACCCAATAGTAAATCTAGCTTAAAATAATCATATTTT AAATTGCATCCTGGATAAACATAGGAATAAGCACATTGTATTATATCTATAGCAATATCT GTGATTTCACTCCTATTTGGCTCAATCCTCCAAACTCAGGACAGGCCCATTAGTCTCTTA ACCATAAAGGGCTGATTCATAGAACCAACATAGCAAAACAAAATCTGCAGAAACATCTCA AAATAATTGGATATATTTGTTGAGCTGATGACATTTTGAAAAATTGATCAAATTGGTCAC CAATTTCAAATATACATCATGTTTTTGACAGACTGAAATTTGCTGAAGCCATTACTAAGG CTTCCATATGTAGGCTAGCCTTCTTTTTCTATTCAATCTGTACCCATATTTAATGTATAG TTAAAATAAAACTAACCATTGCAAACAGTTTAATCTGTAAATGCATTATTTGACTCCATA GTCTTTGAATCAAATTCTTTTTTCTTGAATTTATAGATTTTACAAAGAATGGCAAGAGTA TTAATATTTTAGAGCATCTTGGTAGGTTCCATTCTGATAATGAAATCCTTTGGGTATACA TTCCTATAATTTACAGTCTTGGCCACCTGGGAGAAGTCAAACTTGTAATTCATTAGAAAT TCAAGGAAATTTGGAGAATTACTAGTTCTGAGAGGACTGGCCCTTGGCCAAGCTACACAG TAGCAATGCTTCCATTTGATGCTTACTCTTCTGCTGGTCTTTCATTATTATTAAAGATTT AGGGTATACAAGTGCAGTTTTGTTACACAGATTTTCTGCATAGTGGTGAAGTCTAGACTT GTAATGTAGCCATCGCCTAAATAGTGTACATTAGATCCACTTAGTAATTTCTCATTTGCT GGTCCTTAGAGCTCTCCTTCATATGTTCATATGAAGTGCCAAGAAGCACCTCAAGCAGGA GTAGGGAACCTCTAATGGTGAAGGCCTTCATAGGAATAGTTTATGCTGTTACCCCTTCTG GAAATCCTGAATTTTTATAAAATCTTACAAATAAGTGAGTGGCTATCCAATAATGAAATT TAAAATGGTAAGGTGTATATTTAAAGCAAGTAGTTTTTACTCTGTCTATTCTCTGACACA ACCCCCAGGACGCCTTGCACTAGCCTACTATATCAGTCAGGGTTAGTCATTCATTAAGAC ATCGAATCTTCACTGTAACCAGAGAAGCAGAGCTAGTAGGAGATGTACATTAAGAGATGC CTCGCAAAGAATTGGTTTATGCTATTGTGGAGGCTGCCTAGGCAACTGAAAAATCTTTAT GGCAGGCTGTAAGAAAGGGGAGTCTGGAACTCTTGTGCACAGACTAAAGCTGCTGTCCAC AGCTGGAATTTTCTCTTCTTTAGGGAAGACTCAACTCTGCTTCTAAAACATTTCAATTGA TTGAATCAGGCCCACTCAGATTATCTAGGATAATCTCCCTTACTGAAAATCAACTGATTA TGGACTTAAATCACATCTATAAAATATCTTCACGGAGACACCTGGATTAATGTTTGGCAG AGTAACTGGTGACTGTAGCCTAGACGAGTTGATGCATCAAAAAGACCATCACCTCTACTT TTTAGGAATACTAAGAAAATTATTTTTAAAGTGGATTATTGATTAAGGCTTCTTACGTAA AAATAACTTAGACCTAAAGGAAGTAAAAATGAAAGGGAGTTTGAGCCTAAGGAAGATAAA TAAGTTATTTCTTTTTTTCTTGGGCCACATCAATGTCATGTATGAAAATTCAAATGAGTA GCAAATTTTAGTACCCATCTATTATTTTATTTATCTTTATGATCATCCTGTGGATGATAT ACTAGGTTAAGGGAAGTCTGTTCAAAATTGATTAGCAGTCTTAAAAAAATGACAAATGTA TTAATTACAAGCAAAAAATTTTTGTCACTGATGATACTGGTAAAAGAAAATAATTATTTA AATGGCAGATTTAGCATCATTAGTATTAATAACCAGATATAAATGGAACATAATTATTGC TGCTGATAATCTAAACCCATTGGAAGTGGATTAATTGGATAGATTATTTGGTATTTATAT GTTTTGTTTTAATAGTAGCTATTGTATTGAATGTGATTTTTCTTGAGGGGGAAAAAAAAG AATAAAAAATGGAATAAAAGTAGCTATTATAAGCTAAGTTCCAAAAACACATTATAATTT ATTAAGTTACCATTGCTGACTCCATAATCAAATATAGGCAGTCATTAAAGAATATATTCA AGCTTGCAATTCCCTTTTCTTTCTTTGGAACTCTTTAATCAGAATAGTAGATTCTAGTAA AGAATGCATTCTTCATATCTTAATAATGGGACCATCAATACTTATAGCATCGTACAAATA TTTAGTGTCCCAATCCACATTTTAATAAGACAAAATTTTATTGTGCTGAAATCTAGCCTT TAGTATGTGGTAAAATCAGATTGACTCATCTTATTTTGTCAGGTCAAAACCAGATACAGT TTTTAGCATGACATTTTCTATATTTCAAATCAATACCATACTCTGTGCCCTTTTTAATAT TTAAAAATATTAATGGCTAAGTTATTGATGTATAAAAATGCTCAGTAAATATTTTTCCTT TTCCACCTTATATTTTTTGAGTTGAGTTTCAACACATCACAATTTTTCACCCCCAAAAAA GTTTTCATTTTTTCTCATTGTATGTGTGTGTGTATATATATATTTATAATGATAACCCTT GCTCATTTTCCATGTCCATTCTATACTAGCTCTGAGTTTTGCACTTAGATTCCTTCCGTC CTTCAGCAAACAGCTTTTTCTCTTCCTCCTGGCCTTTCACTGTCTCCTCACAGCCATTGG CAGACAGCACTGGAAGGACTTTTATGACTTGAGATTCAAGTTTTTCTCTCTCAAGGAGTC TGGATGACTCAAAGACACTGGGTTCTTTTTCGGTCTCCTCAGCAGCCAGTGGTCTGCCAT TGTGTGTGCCAGCAGGAGACTTAGAAGCTTCCAGACTGCCCTGTGTGTGGAACCTCCATG GGGCTCTGTACTGCAGTCGTCCTCAGTATTAGTCACTGCACACCGGCTGCATTTATCGCT CTAAAATCCATTTCTCTGCCCCTCACAGACATAACTGCCATCCACCCTCTGAAAACCTGC AGTATTTCTGGAGATTCTGCAGTGACAACTGTTCACTTTATCTAAGTCAATATGTTTGCT GAAAGCTGACCAGAGTTACCAGCGATTTCCTAGTCTCACATTCACATTGAAACATAGGAT ACTTTTACCAACAGCCTGGATTTTTTCCCCTTTTTTTTTGTTTTCCTTGGTTTTTTATTT TTTATTTTTATTTTTTATTTTTTTTGAGATGGCAAGTGAGAAATCTAGGAGTTTTTAGAA TGAAATGTTAACTTACTTTTAGTCTGTTTTTTATTCTTTTGCCAGTTTGACAATCTAGCA TATATGCTATTTATTCACTTCAGTTGCTACATGCTATTCAGATAACCACCTGACTACGTA TGCCAAGCATTTTGCCCCTTGCTTATTTAATCCTCAAACAGTTGTATGACATAGGTATTA TTATCCTCGAAACACTTGAGAACACTGAGACTCAGAGAGCTCAAAGGGTGTTGTCTATCA CGACAAAGCTAATGAAGGACTGAGCTGAGATTCATCCCAGTTTCAAAACCTATACTCTGC CAAGGGAATTCTTGGGGACCTTAGCATAAATTATTAACAGCTAACCTCTGTCAAACATCA ACTGCATATCAGGCACTATTGTAAGACTTTTATATGTGTTCATTCATAACCATCTCAATG ATTAGGTACTATAATTGACCCCACTTTTCAAATGCGGAAGGTAGGACACAGAAAAATTAC AAAATCCGTCCAAAGTCCCACAATTAGCAAAAATCTTGGCAGTCTGGTTTCTGACTCCTT ATGTTTACCCTGCATCCCATAATGTGTGAAGTTAAGTTGCAGAGTCCAAGACTTAAAATT GTCTTTATACTGTCACTATAAAAGAAAAGAGGCCAGTGGTTTGGTTAAGACATTCTTGGG CTGTGGCGAATACTGACTATGCTTTTAAAAGTTGTCTTAAAAGGAAATGGAATTTTTATG GAATCAACCTGATTAAGAGTTTGCCTTACATTATAGACTCCTTGTCCCACGAGTCACTAG GGACTCTCATAAATAGAAATTTGCTATGTTATACCAGAAGAAAGATTTAAAAACTGGCAT TTTTCGAGCAATAGGTACTTGGTAGAATCTTGTGATAGAAGAAAGTAATTTTTCTTGGCA GACTCTAAAGTAGATAATTTGGCAATGTCCTTCTGCAGTCTATGTGCTGTGAACTTGACT CTTGAGAACAGCTGCCTTTCTAGAGAAATCACCTCATTCAGAAGAGATGACTTTTCTGTT TCCAGATTAGTATGAGATTGGTTCAGGAGAGCTCAGTAATGAATTAACTGGTCCACGAGA ACATCATAATGGCTCTGTAGTAGGAACTGAAATTATACTTCACTTCCAGGCCATTATATG ATATTTGTCAAAGAATCATGTAGTAGTGTTTCAAGGATTTATTGAGATATATACCCAGCC AGGATTTTGTTGTGTTGCTGTTTAACGCATCTTAAAACCTCACAATTCACTATTCTAGCA GTTTTTCATTTTATGTTTTGTTCCTTTTTTCCTTTATGCTTTTTTAAAATTTCTAAACCT TAGTCTAGGATACAGAAAGACTGGTGATTCTTTAGAAATAACCATTTCAAAGCCCTGGTG GAAGAGAATTGGTGTTTCTCTCCTTCAGTAATAGACAAATTGAATAACCTGGCTTATTGT TTGCTTGAGGCAGGGAAGAAGTAAAGGATTGGGCCTAAATTTCTTTGACAACAAAGTATG ATCCACAACACTTCGCTTTGCCTGAAAAACTATATGCCAAACCCGGAATCCTTCAATAAT GCTCAGCACACTCAATGCCTTAGAAGTGAAGGTTTTACAGCTCTCTGGTTCTTAAGGAAG ATGATACCAATCTGGTGAAAGGAGTGTGAGGTGTTTAATAAGTTCTTATTTAGAACAATG AAATACAGTGAGAAAAATTGTAGCTCTTTTTTTTTTCTTTTTTCTTTTCTTTCTTTCTTT CTTTTTTTTTTTTTGCCTGCTATTTTAAGGTAGATAAGCAATTCTAAAGAATGAAATGAT TTCATGAAGAAAATACTTCAGAGTCACACTGAGAGTTTGTTTTGTCCTGGAAGGTAGATT TGATTTTTAGCATTTCCTTTTCCATATGGAATCCGAATTCCATCAGAATTTTCTGGTCTT GATTAATGAAAGTGTTACACTAGTCAACACTACCTTTGAGAGAGGAAAGTTGAGTCCTGT TTAGGATTAATGTGGCATAAAAAGTAATGTGTACTAGATCACATATTCCACAACAGAAAG ATAAAACAGGATTGTTCTTATTTAATCTTGAGGTTTCAGTCTTCTAAACAAATGGAAATT ATCACCTTAATCGAATCACTAAATTATTGTTTAATTTAAATAGTATCTGGGTTAGAATCC TCTAGATTTACTTAATGATGAGTGTTCATGGAATGTTTGCTTTATGCCATATTTTATTTC TGTTCTTTATAACAATCCTATAAGGTATCTATTGCCCCCAATTTAAAAATGAAGACAAAA ATAAAAAGCACAGTTACTTGCTCAGGAGCATATTGTTGATGTTTGAGCTGAATCCCTTAC TCCTTCCACTGTGGAATGCAGCACTTTGGCTGAATGTTTGCCCTTTAGTTTATTGTGCTA AAATGTGTGTGTGTTTTTGCCTACTTAATTCTTTATTTTCTTGTCTCCCTCCTTCTGCCC TGATCCTTTTTGAAAGTTCTTTTGTTCTTCTGTAGAAGCCATTAGGTTACTTTTATTGGT AAAACTCTCCCTGTTCATTCCTCTACCTGCTGCCCACCAAGACTTCCAAAGTGCTCCCAT AACATGGGGTCTATGCCTATGACAGCAATTAACACAGTGCATAATGATTTCCCATTTGTT GTGTAGTTCACCTCTTAGAGCAAGGATCTCATTCCCAGCTCCACATTAGAACCTCCTAGG GTGTTTTTAAGAAATGCCAATATTTGAGAACTACTTTTGGAGATGAAATTTAGAGATTTT TTTTTTTTTAGTTGTCTACCTAATTTTAGTGCAAGCTGAGAGTTGAAAATTTATCTTATA AATTCAAGGGCAAGGATAATTCAGCCATATTCCCAGAACTTAGTACCATCCCTGATATAT AACAGATACTTCACTAATAATGACTGGTTGAATGAATGAATGGATGAATGAATGAATGAA TGAATTTTTAAATGCTGACTTACCATGGTTTTCGTAATGTAAGTATTTTATTTATTGATT TGATCATTGTATGATTCTTGAATGCCTTAATGGTGAAATATTATCAAGCATTAAGCAGCA ATTATAATATCTTCAAATTCGGTTAGTGCTTTACGATTTTCACAACCAAATTGTATTTGC CTTTTGAAACCTAGCACAGTGGCTCTTCTATGATGCTTCTTAAGAATTCCAAACTCAAGA AAAATCAGCTTATTGAGATGACTGAAGTTTAACAATAGTGCAATCAGAATGTGAGGGTTC TCTGCAATTTGATTTGGGACTTGAAGGATCTTTATCTACTGGTATGTTATATCCTGATCA AACTTTGCATCAGAAAGCAAGAGGCATTTTAGAATTCAACAGCCTGCAAAAGGATCCTGG CACCAGCACACAGCAGGTAGTAACCTGCCTAGGGCAACTTCATAGGATAAATTGTTTGTT TCCCTAGGTAGCCATCAGGATATTACTAGATTTCTTAGAGCCATGAGAACATTAAGTGGG GTTTTCAGGACTATAATATATCCTTCAGCTCTCATTTCAACGGCAATCAATGTTCATAGC CCTCCTTTCAAAGCACTGGCAAACATTCTGGTATAATTAATGTCACTGAGGTATTGTTTT TCCCATTGCTTTCTGTGTGTTTTGTTTTTTTTTTTCTAAGAAAGGCAAGTTACAAGACAG ATGTCTTATATGAAAAGCTATTATGCTATTATGTAATTTGAAACAAAAGGCCAGTCTCTA ATAATAGTGTGGGTGTTAGAGGGCACAGAGTGAATTTTCTTGAATGAGATAATTTATGGA AATTCTCTAGGACACCATATTTCAACTTGGCATAAAAATTCCAGATTCATTTAACATATG CATGGTGAGAACAACTAAGTTTTAAGGCCAGTTTGGTAAAGATTCATAACTTTGTCAGTT GATTATGTCTCTGCATAGGATCATAAGTAGTTTTAGTGTTGACAAGTACAGATTCTTGCT GGGGGTTGTGTGAAGTTTAATTCAGCAATTCAGTACAAATCAATAGCTACTTATTGAGGG CCCACTGTTTTCACCTGGGTATTTTGAGGAGAAGGCAATTGGGTAAGACAAGGTTCCTAC CTTCAGGGAACATATGGGTAGTTGAGTAAAATTTCTACTATTGGGTAGAAAAACTGCAGC TTTTGATTATAAAATAAAGTTTTGTTGCCAGTAAATTAGGTCTATAGAATAACACCATGG TAGGAGAGATTGATTTAGGGAGAGTTAAATGTTTTCCCATTTCCTATGAGTATCTTTCTT TTCTTTCAACTGCAATCAGCAACTTATTTGATAAGGGAGGTTTGGAAAATTATGTACATT GTTTATTTCTGAAATTAAAATAAAAATATGCATTTTCATAGACATGAAGAGCATACCTTT ACTCTTAAGTATCTGAACACAAGATGCTTTGGAGGAATAAGTTCGCTGAATTAATCTTTA TAAATAACTCAGTTGCATTCATCCTCAAGTAAGGAATTCAAGGGTTGCCTTTGCCCATCT GTTTGACAAAGTATGAATCTTAACATCACGGTTAAGTGAATTATCTGACAGGATGAACTG CATATACACTTACAGTGAGGCTTAAGGGTGCTGTGATACTTACATGAATTGGAGTATTTT GAAAATGTTCAGGTTGACTGCAATGCTATATTATGTTAGGAATTGACTAACATGGATAAA CGGAATGTGATTTTTTACAATCTGTATTTTCAAAGGTTTTTGATTTTCATTTACCCATCC AGGTTGCCCCCAATACTACCAGTTTCTCCTCATCTTTCATTATTTCACTCATTCCTTTAT GTTATTTGCTTAGTTTGGTGTCTTTTTATCTCTCATATAAACAAATATACGTAGTCTAAA GCAAGGTTTCTCACACTTGGCATAATTGACATTTGAGACTGGATAATTTCCTGTTATAGG TGGCTATCCTGTATAGCAGCTTACTGGCACTAGATGCCAGTAGCACACACATCCAGTTGT GGCAAACCATCATATCTTCAGATATTGCCAAATATCCTCTGAGGAGCAAAATTGCCCCAG TTGAGAACCACTGGTCCAAGTCAACTTCCTAAATCTTCTTCTTCAGTCTCAACTTCCTTC ATGATAGCTGCTATTCTAATGATTCTAATGCATTATTTTACTGAGAATCACATGTCTCTC TTGTGCCACTGAACCTCCAATGACTCTTACCATAATATTCGAGGCCCTAACTGCCCTTAC CCTGTTTTATTTAAGTTTCATTTGTAGCAAAATACTACATGCTCATGTTAACAAATGAGA GAGTACAGAAGAGCTATGAAAAGCAAGTCACCTGGTCTCCTTCTCCCCACTCTCATGTCT AAGAAGCAACTTTTTTTTTTTTTCCTGAGACAGAGTCTTGCTCTGTCACCCAGGCTAGAG TGCAGTGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCTT GCCTCAGCCTCTTGAGTAGCTGGAATTGCAGGCACTCACCACCATGCCCGGCTAATTTTT GTAGTTTTAGTATAGATGGGGTTTCAGCATGTTGGCCAGCCTGGTCTCAAACTCCTGACC TGGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACCGCTC CCGGCCTTAAGAAGCAACTTTTAAAGAACTGTTGCTGATTTGCTTCTTGCATTTTTCTCC ATAACTCTAGATATGTCTATACTTTTGTTTGATTTATCAACTTTAGGCAACATTGTCTCT CTGTTTTCAAGATGAAGTTTTAGATCAGTTATATAAATTGCCTTTTTTCTTCCCTTTTTT CCATTTTATGATATTTAGGTGATTGTATTCATGTATGTTGATCTTGTAAACATAATCTAT TATTGGTCAATCAACTTTCAGGACCACATTGTTGTACTTTCTGGAGCTAGGAGGGACTAG AGACCCAATTGATTGTATCTCTCAACCCTCCCATTATAGTAAGTTGAGAACTTGACTGCT TTTACCTTTTCTTCACCTCTTCCATATCCTACCTGCTGTCAGCCGTATTTTTATTTACAC TACTATTCACAGTGTTAAGATTTTTATTCTGCCTTGCAAATGCAACTAAGTCTTATGTCC TTTATTCTTAGGTTAACTCTTTAAGTTGAAAGTCATTAAACCAAATTTACATTATCATGA CTCTGCAGACATTTTTCAATATTACATCAAGTTTAGATCTATAATTTTATTTTATTTTGC ATAGGTCCAAAGTCATGATCCTTGCATCACATGGAGTATAATGATTAGTATCAGTGTCAG ATAAATTCTTTTTTTCTTCAATTCTTATCAGCTGTGAAAAATCATGCCATCTTTTACAAG TAACTCCTATCTTTCTTGTGAGTTTTCATTTGCCCCGTTTCTTGCACTATTTGCCTATTT TCCTTCATTATAGCCACATGTTTATGAGGTCAGTCTTTTCTGGATCCCAACCCACCACCT GGGTTTTTTTTTTCATTGTTGTCCTAGGTAGGACCCATAGTTTCCCGTGTCTTTCTAGTT TTTGTTTTATCTTCATTTTGTTAGGACATAGGTTCAATTAACTTATAAAGAAAAAGTGTA TGGGCAGTCAACTTTGCATGGGTACTTGCTTGATGAAAAATTTTTCTATTTTACTCTCAC CTTAATTGATAGGTTGGCACAGAATTCTAAGTTAAAAATATTTTTGTCCACAATTCAGAA GGCACAGTTAGACCCAATGCTGCTGAAAAGACATACTGTTTTTCTTTTCTAGGTGACATA TTGTTCTCTTGCATTAAGTTTCACTAAGTTAAGCCATGGCGACACACAACATAAAAATCT TAGTGGCTTGCAACATGTTAGCTTCAGATTAACTTTAGCTTGGTCCCACATGATCTAGAC TGAAGAATTAGCCCCATCTGGGAATGCTCACCTCTTGGCTAGAGAAAGGAGCTGTGGTAG ATCAATGTCGCTGCTTGGACATAGCATATGTTATTTCCACTCATATTTCAATATGTCCAA GCTTGACATTAATGTAATAGGAAACATTCTCTCCAAGCCTCCTCCTTTTTTAGCCCTGCC CTCCCCACAAAGAGAAGACCCAGGGAGGGGCCCTGAAAGATGGGCTCTTTAGAGGGGGAC AGTGAATAACTAGGAACAATAAGACAATGTACCACACTCTTGAAAGAGTTGAGGACTTTC TTTTTATCCTGAAAATTAATAATGAGTGTCCAGCTGGTTCTTTTATTCATTTATTATTAT GCTGGAACTTGGTGGATCTACCCAATCCAAAAGACTTAAACCTTTCTTGTGGGAAATATT TTATTATCTTTTAAATAACTCTTCTTCCTGTTCTTCATTTCATTCATCCTAGAAACTGAA GCATCTCAGTTGTTTTTATCTGTATCTTTTATGTTTTTATTTTTTAAAACACCTGTGTCA TTGTTTTGTCTTTTTGCTCTATGACATTTTTCCAGGCATTTATTTCAATGTATTTTTTTT AAAATTGACAATACAAATTATTTTTACTGTTTTCTCTCAAAATATTTCATTTTTGTTATA TGAATATAAAACATTCTTGAACTTCTCCGAGTAGATTTGTTTTTGTTTTTAACCTTTATT TGAAGTTCAAGGGTACAAGTGCAGGTTTGTTACACAGGTAAACTTGTGTCATAGGGGTTT GTTGTCTAGATTATTTCATCACCCAAGTATTAAAACTAGCACTATTAGTTATTTTTCCTG ATCCTCTCCCTCCTCCTCACCCTCCACCCTCCGAAATATTAATGGAATTACTTTAATATT CTTTTCTGCTTCCTGAGTTATCTCCATTTCCCTTAGGGTGAGCTTTTCTGCTTATTTCTT TTGGCTTCCTTTTCAAGAGTTTCTGACTAGAAGCATTGTGAGGGAGTAAGTCCAGTTTTA CATTAGTAAGTTGCATGTCAGGAAATGGTTGTCCAATATGCAAGATTGCAAAAGCTCCAC TTTAAAACTCCGGTGTACACACAGGAGCCTTAAATTTGCCCAATTAACTCAAGGCCCTAT TGAAACCCTTGCTTCCTACATACCAGAGAGTGTCTTAGATTTTTCTGTCTGAAGATAGGA ACCTGGATTGATTTCCACCCCTGGCAACAATATAGGAATTGTAATAAAATCTGTGCTTCT TTTTGCAAAGCCCATTAGGAAATAAAAATGTATTCGTGTTCCTATAAAATTTTGAATTTC TCAGAGCTTATATTTTAGATACGTATGGAGGTCTTAGTCAATCCTTTTACTTAGTAAGCA TAATAATCAAGTTTGTCTGGCTTATTTGTGCTCCTTCTCAGTGTCAATATGAACCTTGGA TGATTTGATGAAGGGCCCTAAAGTAAAGTCTTTCAAACTTTTTAAATCTAAAATTAATGG TAATGCATTTTACATCAAGACTCAGTAAGCACATATAAACATAAATATGCATTTAAGTGA AATAAAAGTTTCACAAAAGTGCCTTACTGTGTACAAAGCAATTTTATGTTTTCTATTTCA GATTTTAAAACTGTGATCAAGATTTGCTAAACTGGTTTATGACATACTGATAATTTTATA GTGTAAAAAATAGTGCTATAGAACATGGTCCTGAGAACTAAATAAAAATGTTCTCTAGGT TTTTAAATAAATGTCACAAAATCTCTATTCTGAATATATTGCCTTTATTTTGTAACATTG CTCCTTAACTCAGAGGCTTATAATTTTTGGCAGGCTTTGTTATCCAAAATTTTCTCCAAA ATTAAAGCTTAGGAGGAAACCACAAAACTAAAACATAATAATTGCCTAGATTAATAATGG ATATATGTGTCCATTGTCCTAATTAGGATAATGTGTGGTTAGTATCGCCTAGATAATAGT ATCTTCTGTATCTCCTAGATAATATTTCTTATAGCAGGGAATTTACAACATATTTCTCTT CATCAAAAAGATTTAACCTTTGTTGCTTGATTTTGGTCCACCTCTGTATTTAGAGATCCC CTAAGGAAAGCCAGAAACCAATGGCCAAGGACTGTGCTGCAGATTCCCCTCCTGCAAGTG GCCACTTATGCCGAACTCTTTTCTAAATATTTTGGTGAAAAATAGAGTCAATCACACTTG CACAAGATTAGCTGAGCACTCCAAGATTGATTTAAATCTGGGACTAGCAGAAAAAGGGAT TCAACAACAAAAATAAGACGTGATATTTTGTTATGCAAGGAAAAGAATTTTGTATTCAGA GCTGCTTTCTTAGAAAACTAGAGACAATGACAGTGAGTTCTAAATAAAAAATACATTTCA GTGAAATAACCCATGACTGAAAAGTAACTATGAGCACACCCTTGGTTCACATCTATCAGT TATGTATTGCATAAAAGAGGGTTTGTTTTCAATTGTTATTAGAGGAATTGAGTACCTTTT AAGTGGCTAGAAAGTTGTGTAAAGTGCAATTTTAAGTGGCTTTTGTTATGCTACTGAAAA GTCTTAAGTGTTGGTTAACTTATATGAAAGAGAGTGTGAAACAATCCTTGATAACATTTT TTTCTTTCAGTAGGGTTTGTGAGGAAAAAACTGTGGCTGAGGATTCTTTTAAGTAATAGC CACACAAATAATCGCAGATTACAGTGTCATACAACTCCATTAACTCGGTGAAGGAAAATA ACAACATTTTCATTTTAATGAGATGTCAGCTCCCTCCCTTGCTGTACTGCGCTTCTTAAT GTCCTTGCTGTCTGCACTGACTTGGGGCTCCAAGGCTCTCTCATTACTTGGCAATTCCTT TCTCTAATTTCTTGTGACACACGGTGCTTAAATCCACAAGAAATGTGAGGTAAGGCTGAG AGAATTCCTGCAGACTGATTTACTATATGCAGAACGCTCATTTGCATTATTCATTAGATA AGAGCACTGATTTGCATCTCATTCTGGTTGCCTCCTTTAGGTGAAAAAAAATGCCAGAGT ACTCTCAATATTCCCCTGTTTTTTTTATATTAATAATAATTATTAGGGGAATTAGGGTTG ATTCCTCTCCTGTACCATTTGCAATTTCTCTTTAAAAGAAAACCCAGAAAACTCTAAACA CTTCTAAACCCCCAAACCAATGTGCATTTTCCCTTTTGTCTTTAAAGTATTTGAAGCTTT AACATTTGATAAAAGATTTGAATGCATAAATGTATTTTATTGAAATGCAAGAGAAGACAT TTATGATCCATATCTAACATTAGGAATGGGAAGGAGGAGGAAGCAGTTAAAAAAAGTATA GGCACAAGTACAGCATTTGAGTCTCCCCAAATCTCATTTTAGAGAGATTTCCTAGCAACA GAAACATGCCACATGTTTAATGATACTGCCAGTAATAAATTCTTCCCCCCTTGATGGTCA AAGCCAAGTGAAGAAATTTTGCTTTGCATTTTGTTTTATTAATTGCTTTGTCAATTAAGA TTATACTTTATTGTAAACATCAGCTCATCATTATTAAAAAGTCATTGATGTCTGACTATG TGTTGAGCTCTGTGCTGGCACCTAGAGTTCCTGTGTTAGATAGATACAAGAAAAAAAATG ATAAAATATCCTTCATTCCTTGCCTATACTCAATTCCCCATGGTCCTAGTAAACTTCCAA TCACTCACCATTTCCTTGGCACAGACTCTGTAGGCTTTATTAAATGTCATCTAGTGATTC TCTGGGATTTTGAGATTTGAGCTGCACAGGAGACCCGATCTACAATCACACATTCAATTG GGACCACTGATGCATTCACAAAGGGAAAGCAGGGCATAGCATGGATGGCAACCTTCTTTA TCCTTCATGAGAGACAAGGACAGAGGAGTCAGAGACCATTCCTCTGTCCGCTGATTCGCT GTGATTCAGTTGCCCCTTGAATAAATGATAGCATTCTGTTGAAGGTTGCAACAAACCTAG TGTCATGGATCAATCACAACATCCAAAAATGAAGGAGAATTCCAGTGATATTAAGGTCAC ATTGTAACCAGAAACATGGGATCTAGCAGGCTGGGATGATTTGTTTTGAGTAGAGGTTTT GTACAAATTGCACATTGTTTCATCAACACAGGTAACAGAAGACTGAACCGATTCTTTTGC TCTACTTCTTCATGTCTCCCAGAGCATTTAATTCCGTGCTGGAAGAGGTCATCACAAACA TTCATTATCCTTGTTCATGGGGCACCCCCTACCTTAACTGCTGTTTATTCTTGTCTGGTT CCTGTGATTAATGCTGGAATGCAAAACAGCTACTTCTCTTCTTTATGGCTGTATCTGGCA CACTGATCTGTTTAAGGTCTTTGGCATCCCCATAAGGAACACCAGTTTTGAAATAGCCCT CATTTGCATTTAGACTAAAACTAGAATCCAGTCCAGGATTTGATTTTCGGGAAGCGATCA GTTAGATAAACCTCAAATTGTGTTTTTGTTGCAAGGGTGATTATTTAAATATATTTTTTC TACTTGAAGCATTCAAATATTATCAAGTAATAAAGTTGTATTTCTCTTATTTAATGAGGG CCAAATGGTCCCCTTTCAAAGTAACAAGCACTAGTATTAAAAATGAGGGGCAGCTTATAT TTGGTTGTATTAGTTTTGGATGATTATGCCACTTGGAGGACATCGAGCTTTTGTTTTTGT TAATGTCACAATGGGCTTATAGTGCCATGCTTCATAGAAATGTCACTGCTAAGCTAATTC TACTATGGAAGTCATACTGAGGTTTCAGAATCCCGAATGAGCTAAGGAGATTGCATTTGA ATGTCTCATACACATTTCAAAAATAACCTGGACAAAAGACAACTGTGATTTCCTCTCCTG CACTCCTTAGCCCCCTTCCCCCAAAACTGATTATCTTAGCAAATGGGATCACCTTTCAAC CAGTTGCCTAAGCCAAAAACTAGTAGTCCTATGTGATCCCCCTCCCTTTTCCTGCCACAA TCTGATTACTATTGCTGTGTGACAAACTATCCCAAAACTTAGTGGCATAAAGCAGAGAAG AGCATGTGAGATAAAAGATGCTGTAGTAGCCATCTTCAGTCAGTACAATCGATCTATCTA CTGCCCACAACTGTTCACAACCTTTCTACATGTAAAATACACCCAGTCCTTCCCCCAACA TTCCCAAAATCTCACCTCATGACTTTGAAGTCTAGGATGTTGTCATCCAAGTCATGCCTG GTACTGATGAGGCTCTTTGGATGCAGTTCTCCTAGCATGGCTCCTCTTAATTTCTGAAGA GCTGTCAACAAAAGATTCCAATTGTCTTCTTCCCACATACCACCATGCACTGGGGGTCAG GCAAGCATTCCTGTTCAAAAAAGGGAGACATGGGAGACACACAGCAGTCACTGTCCAACA GCAGTTCAAAAGTCAATTGTTGCCAGATCCACCTTCCCAGCATCTGACACAACTTTCTGA GTTATTCTTCCTTTTCCATAGTAAATGGCCGGTTGTTGCCACTGAGTAGTTTTCTCACCC TGCTTCCTGCCGAAAGTAGTTCATGGGCCCAGAGACCTCACCCCCTTCATTTTATGGTGT ATCTCTCATTTTAGTTCAAGCTGATGGAGTTCCTTTAAAAAAACTTCATGGCTTCCTGTA TCAATTTATATATCCACTACATTCGACAAAAGACACACCCACAGATCTCTTTAGTGTAAG CCTTTTTCTACCATGGGCTTCCAGTGAAGCTGCCATGGACCATCACCCTTAAGATTCATG AGTGCCTGTTGTTTTAAAAAGGCAGGTTCTTAAATCCTGAAGGCTTTGTGTATGTGTGAA AAGTTTATAAGGAACCATCTTAAATCTTTCCAAAACCACTCCAAAATTTAGTGGCAGAAA ATATTCATTTATTATACTTAAAGATTTCTGTAGATCAGGTATTCAGACAGGGTAAAATAA GGATGGCTTGTCTCTGCTCCACAATTTCTAGAGTTTCCACTGGGAGAACTCAACAGCTGG GGACAAGTTGACATCTGGGATTGGGATCATCTTGAGTTGAGGTGTCTCCTCACGTGTCTG GCAGTTGATGCTGGCTGTCAGTTGGAACCTCACTGAGGCTACTCACTGGAGCACCTTCAT GTGGCTTCTCACATGGCCTGGGCTTCCTCACTGTGTGGTGAACTCAGAGTAGTCAATTTG TTACATAGCAGCTTTGAGCTTCAAGGTGAGTCATAGCAGACAAGGTGTATTTTAATTTCC TGGGACTGCTGTGACAAAATGCCACAAATTGGATGGCTTAAAAGCATGCATATATCTTCT CACAGTTTCAGAGGCCAGACGTCTGAAATCAAAGTGTTGGCAGGACTGCACTCCCTGTGA AGGCTCTGGGGAAGAATCCTTTGTTACAGATTCCTATAGCTTGTGGTGGTTGCTGGCGAC CCCTGGCCTTCCTTGGCTTGCAGCTGCATCAGTCCAATCTCTGCCTTCCTTATCTTTACA CGGCCTTCTTCACTCTGTGTGTGTCTGTGTCTGTGTGCCCTTTCTTCTTCTTAGAAGGAC ACAAACCATATTGGAATTAGGGTCCATCCTAATCCAATATGTCCTCATCTTACCTAATTG CATTTGCAAAAACCGTATTTCTAAAGAAGGTCACTTTCTGAGGTTTGAGTGGCTATGAAT TTTTGTGGGACACTATTGAAGTCAGAACAAGGTGGAAATCACATTGTCTCTTTAGCCTTG AAAGTTACGTAGCATCGTTTGTGCTGTGCTTCAATTGGTTAAAACAGCCACAATCATACT GAGGTTTAAAGGGAGGAGACTTCCAGATGGGGGACAGCTAGGATCACATTGTGGAGCAAT ATGCGGCCTGTGAAGTGGCATTGTGTTCATTTTTTAAAAATGCAGTCTACCACATCCTTA TCCAGTCTGCGACCAACTTCTATTTTTTTTTAAAACTTGTATACGTTTAAAGGGTAAAAG TGCAGTTTTGTTACATAATTATATTCCATAGTGGTGAAGCTTGGGCTTTTAGTGCAACCA GCACCCAAATATTGTACATTGTACCCACTAGGTAATTTTGCATCCCTCGCCCTCACGCCC ACCCTCCCACTCTTCAGAGTCTCCAATATCTATTATTCCACTATGCATGTGCATTATTTA GCTTCCACTTATAAGTGAGAACATGTGGTGTTTGACCTTCTGTTTTTTAGTTATTTCACT TAGGATAATGGCCTCCAGTTCCATCTGTGTTGCTCCACAAGACATGATTTCATATGGACT TTACCTTCAAAATATATCCCAAATCTGTTCACTTGCCTCCTTTGCCACCCAGTCATGCAA AACACCGTTATCTCTCATCTGAATTATGGTATTAGACTCTTATTTGATCTTTCTGTGTCT ACTCTTGCCTCTTCTAAACCACTCAGCACCAAGTGGCAATAAAAGAGATACTAAAACTAT GAATGGACTTATGTCACTTCTCTGTTTAACTCCTTTAGAGACTTCTGATTACACTTAGCG TAAAATCCAGATGTGTCTCAGAGGCCTAACTGGCTCTGCATGATCCCTCCGAGCCTGTCT CTTCAACTCTATTCTATGTCAGCTTCTTCTTCCCTATGTACTATTAGGTTGGTGCAAAAG TAACTGCAGTTTTGTCATTAAAAGTAAGGCATTAAAGTAAAGTACTAACTCTCCGGCCAC CCAAGCCTTCAAATTGTTCCTGGACCAAGAACTGTTTGTACCTTAAAGACTTTGCGCTTG TGTTTTCTTCTGCCTGGAAATCTCTTTATTCAGGTCTTTATGAAGCTCACATTTTGCACA CTCTAAGTTTCATCTTAAATGTTATCTCTTTAGACAATAATGATAATAATAATTAAGTTA ACATATTTTTGAGTTAGCTCAAAATATAGGCCATGCCCCAGAACTAGACATTCTACCTGG ATTATCTCTTGCGATCCTTGTAACATCTTATGAAAGAGGTTTTATTATTATCCTTATTTT ACAGATAAGGAAACTGAGGTTTAGGGATGTAAAATAATGTTCCCAAATCATACTGTTGCA CACTTATGCAGTATACTGTGTATGATGAAGCACAGAGTTTAGAATTACACACTGGGCTTT CTGGCTCCAAAGGCTGCCCTCTAAACTACCAGTCTCTGTTGCCTCTAGAGAGAGGCTTGC CCCTCATTTTATTCTCAGTTATAGCATCTGTTTCTTTTCTTCGTTTTGCCTATTACTCTC TGTATTTTTTTAAAAGAGTGTATTTATTTGTTTATTGCCTATCTTTACCACTAGTATTGA AAATTTTTATTGTTATTTTTCATTGTTATACCCTAGCACCCAATGCAGTACTTGGCACAT AGTAGGTACTCAATAAGTAATTGATGAATAAATTTAGTAATGTGTTGATCTAACAGCTAG CTTTGGGTATAAGGTCAGGGATGATTTATAGCTTTTTAAAATTTCCATACTCTTACCACC AACCAATTTCAAGTTGCAAACAGTTTAACAATTGGCTTACAAGATCTCTGAAAGTTAAGC TCTAGCATATCACTGAATTAATGAATAAATGAATGAATGTTGCAAAGAGCAGAGTAGCTC ACCCACAGTAATTGGTTTCCTAGCAGGATAGGGGGTTGCCCTTTCTGCATAAACCCTTGT GGTTTCAGCTCCAAACAGATCACATACATTGGTGTGAGGGTTCAGAGCACAGCTGTTATC AGAGCTGCAAAAGGACAACGAAGAGTTAACTCTGTATCTGAGATACTAAATATCGCTACA ACAATGTGGTGAGAAACACTGAGACCAGATACTGTCATTTCTTCATCTTTTTTCACTGCC TCAGGTGTCGGCAAGGACACATATGATGCAGAAGCAAGGGCAGAATGACTTTGTTTTACC CTTTAAAGGGAGAGGATGGCAGAGATTGGAGCAGGAAGGAGTGAAAAGAGGAAAGGGGAA AAAGCCATTAATATTTTACATTAGGCTTAAAAATTCTCAGTTACAGCTTTGGCTAGGAGG AAACATTTCCTTGAGAATGTTTGTTAGATGTTTTATGCTGCATGATCATACAAAGGACTG ATTTATAATTAGTCCAGTTACTTACCTCTGTGTGTAATCGGGAATGGCATAGGCATTTTT TTTTGACAACTATGTGCCACTCAGCGTTGCTGATTACATCTTATTTGACAGTTTTTAATT ACAAAAGTATCAATTGATTTTTTTTTTAAATCAACAGTTCCGTAGTCCTGATTGATGTGA AGCGACAATAGATCTGAATGAATTTGTAGAACTTGGTGGGACTGTATTTATCACATTGGG TATGAGATTCCTGACATATGTTGCCTGGCTGCAGCACCAAGGCAGTAAGACAAGGGGTGA TGCTTGGATGTCTTGTCTCAGTCATGGCCAGGGTGTAATGTGTCTGTCATTTAACTGACA GGTCTATACCTTGGCCCCAGATGCTACAGCTCTTCACACTCTGCATAAGTAATATACCCC CTATTATGCACATTCGCTCTGGGATTTTGAATGAATAAATTCTGAAATGCTCTCACTGAA AGCTCCAGAATCCAGATTTTTTAAAGTGCACATGTAATTAATTTTGCTTTAGAATTTTGA ATTAATGCCAAGAGAAATGCCTTGCTCTATCTCTTTATTAATTTCCAGGTATGAGCCTGA AGAAAACAGCCAGCACTTTGCTTGAAATCATATGAATAATATTAGAGTAAGAATGTCTCT GTTGGAGACAAAAACATTATATTTGGGTCTCTTGGTAATCTATCCATTGGTTAATGGACC CAGAACCCTCTAGACAGTTCACAAATCCACATAACAGGGCAGAATTTTGCATTAGGTTTC CTGACTTAGCTGAAAACTGTGACAAATCAGATGCAGCCAAAGAGTTCCCTATTGATTACA AATGTAGGGATCAAGAGTAAGTTATTCCATCTAAGGCAGCATTTATTTAAATTTAAAATG GTCCTTCCTGGTAATCTCAAATTGGATAATGGCATACAAATCAATGGAATTTTTCAGAGT ATTAATTCCATCTCATTTGAGGGGCTTCCTATTCAATATTTGAAAGAATAGGTGTTGGTG TACAGTCAAATTTTGGGGGACTGTAAGAGTTTGGGTGAATATAGGCCTAGCACCGTGGCT CTCACCTGTAATCCCAGCACTTTGGGAGACCGAGGTGGGTGTATCCCTTGAGGCCAGGAG TTCAAGACTAGCCTGGCCACGTGGCGAAACTCCTTCTCTACCAAAAATACAAAAATTAGC TGGGAGTGGTAGTTCACGCCTGTAGTTCCACCTACTCCAAAGGCTGAGGCACAAGAATCT CTTGAACCCAGGAGGCAGAGGTTGCAGTGAACCGAGATCAGGCCACTGCACTAAAACCTG GGTGACAGAGACAGACCTTGTCTCAAAAAAAAAAAAAAAAGTTTGGGTGAATTTAGAAAA GAAAATGAAGTTTTGGGACAAAATGTAAGTAACTCTTAGTTTTTTTTAAAGGAAAATAAA CAACCAGTGGTCTTGAAAAAAAAAAGGCGGGGGAGGGGTGTCAAAATTGCAAGCCCTGTC AAAGTACTGTTTGCTACACAAGTATCTTTCATAGTTTGCCAATATCATTGACTCAATTTC TTTCTCTAGAATTTGAGCATAGCACTAGGTTCATATAGGTAGGTTATAAAATGTTTTAAT ATTCTCTACCTTTAAAAAATATCCTAGCTGAATGTATAAACCATCAGTTGCCCATCATCC TATCTGGTGTATAAATTCCCTATATATCACCCTGGACGACAAATAGTTCTAGCTAAACAC ATCTAAAAACAGAAAGGCCTCAATGTCCTAAGACAACTGAAGCAAACAGCTATGGCCTAC CAAGTCAAAAGTTAAAAAAAAAAAAAGGGGGGGGCCTTACTGGATCAGGTATTTGTGTAC TAGTATTCACAGCAGCATTATTTGTAACAGCCAAAAGGTGGGAATAGCCCAAATATCCAT TGACAGATGAATGGATAGACAAAATGTAGTATATACATACAATAGAATATTAGCCTTAAA AAAGAATGAAATTTTGATACATGCTACAATATGGATGAATCTTGAAGATATTTTAAGTAA AATAAGCCTATCACAAAATGGCAAATATTGTACAATTCCACTTATGTGAGCTCTCCAGAG TAGTAAAATCCTAGAGACAGAAAGTAGAATGGTGGTTTCCAGGGACTGAGAGGAGGGAGG AATGAAGAGTTATTGTTTAATGGGCACAGAGTTTCAGTTTGGGAAAATAACGTTTCGGAG AAGGATTGTGGTAATGGTTGCAAAGCAATGTTAACTCACTTAATTCCACTGAATTGCACA CTTGAAAGTGGTTAAGATGGTAAGTTTTATGTTGTGTTTATTTTACCACAATTAAAAACA AAACAACAACAACAAAGAGCAAGATGTCTTAGAAGAAGCCAAGAGTTCTTGAGCATCTTT TTGTACCATCATTTTTTTAAAAATTTTATTATTATTATACTTTAAGTTTTAGGGTACATG TGCACAACGTGCAGGTTTGTTACATATGTATACATGTGCCATGTTGGTGTGCTGCACCCA TTAACTCGTCATTTACATTAGGTATATCTCCTAATGCTATCCCTCTCCACTCCCCCCACC CCATAACAGGCCCCGGTGTGTGATGTTCCCCTTCCTGTGTCCAAGTGTTCTCATTGTTCA GTTCCCACCTATGAGTGAGAACATGCGGTGTTTGGCTTTTTGTCCTTGTGATAGTTTGCT GAGAATGATGGTTTCCACCTTCATCCATGTCCCTACAAGGGACATGAACTCATCCCTTTT TATGGCTGCATAGTATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAGTCTATCGT TGTTGGACATTGAGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCGCTATAAACAT ACATGTGCATGTGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATATACCCAGTAA TGGGATGGCTGGGTCAAATGGTATTTCTAGTTCTAGATCCCTGAGGAGTCACCACACTGA CTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTATTTC TCCGCATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATCGCCATTCTAACCGG TGTGAGATGATATCTCATTGTGGTTTTGATTTGCATTTCTCTGATGGCCAGTGATGATGA GCATTTTTTCATGTGTCTGTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGTCTGTTCAT ATCCTTTGCCCACTTTTTGATGGGGTTGTTTGTTTTTTTCTTGTAAATTTGTTTGAGTTC ATTGTAGATTCTGGATATTAGCCCTTGGTCAGATGAGTAGGTTGCAAAAATTTTCTCCCA TTCTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTTTAG TTTAATTAGATCCCATTTGTCAATTGTGGCTTTTGTTGCCATTGCTTTTGGTGTTTTAGA CATGAAGTCCTTGCCCATGCCTATGTCCTCAATGGTATTGCCTAGGTTTTCTTCTAGGGT TTTTATGGTTTTAGGTCTAACATTTAAGTCTTTAATCCAGCTTGAATTAATTTTTGTATA AGGTGTAAGGAAGGGATCCAGTTTCAGCTTTCTACATATGGCTAGCCAGTTTTCCCAGCA CCATTTATTAAATAGGGAATCCTTTCCCCATTGCTTGTTTTTCTCAGGTTTGTCAAAGAT CAGATAGTTGTAGATATGTGGCGTTATTTCTGAGGGCTCTGTTCTGTTCCATTGGTCTAT ATCTCTGTTTTGGTACCAGTACCATGCTGTTTTGGTTACTGTAGCCTTGTAGTATAGTTT GAAGTCAGGTAGCATGATGCCTCCAGCTTTGTTCTTTTGGCTTAGGATTGACTTGGCGAT GCGGGCTCTATTTTGGTTCCATATGAACTTTAAAGTAGTTTTCTCCAATTCTGTGAAGAC AGTCATTGGTAGCTTGATGGGGATGGCATTGAATCAATAAATTACCTTGGGCAGTATGGC CATTTTCACAATATTGATTCTTCCAACCCATGAGCATGGAATGTTCTTCCATTTGTTTGT ATCCTCTTTTATTTCATTGATCAGTGGTTTGTAGTTCTCCTTGAAGAGGTCCTTGACATC CCTTGTAAGTTGGATTCCTAGGTATTTTAATTCTCTTTGAAGCAATTGTGAATGGGATTT CACTCATGATTTGGCTCTCTGTTTGTCTGTTATTGGTGTATTTTTTGTACCATCTTACAC TCTACTTGCTCTGTGCCCCTGTGTGTCTGACTTCTCCTTCGTGCTTTCGACCTTCTTTTT ACACAACCATCCTGGATGGATAAGCCTGCCCAGCGTGTTTCCTAAGACATAAGTAGATGG ATTTTGTTCAAAAGCCTTATCCCAAGGGTTGACATCAGTTCTAATGTGTCTCACTATGGT TTCTCCCAGGAGTCTTCTCAAAACCTCTTGGCCCCACAATCTCAACTGTTAGCCCCAAAT GCCAGTATCTGGAGATTCTTTGCCAGGTTAACCCCTACTTTCCCCTTTCAACTCACAGGG GCCCTAGGGACACATGTATTTGCCTGAAATCTCTCTCTTTTCTTGTGTTTGCTAATTTTC TGGCATATCTTTTGCCTATCTTGATTTTTTGTATTTCCAAAATGTGTACATAGTTTAAAA TTTTAGGATACAAATGCCATTCCTGGGTAACTAAAATGGTCTTTGCTACAATTATTATTC CATGTGTGAGTACCTTGTGCATGCTTGGACATTATCAGCAAAGCCATGGGATTTGATTCT AATGTTTATTTTAATTCAGCTGGTTCACATTATATAATAAAATCTGACTAATTCTGAATA ATGGAAGTTAAGACTACTGTGATTTCCTGAAAAATGAGAATCATTGACTAATTTTCAACA TAATTAAATTGTTTTCCTTTCAAATTCCATGTGTATCATAAACAAAGTAAATAGAAACTA ATAGGTAAAATGAGATCAGTTACAGAATGATTATGAATCAAAATATAATGGCCTAATGAA ATAAATGCCCTTGAACATATACTAATTGTTCAATGGTTAGACTCAGAAATTAAAAGTACC TTGATAGGTGCTCTCATTGTCTTCTCTCCTGGACAGTTGGATGATTTTCTCCCCAGGTAT TCTTCTTACCTCTTTGAGAACCCCTTCCACAACTTCTTCACTCTTGTCACTTCTCAATAC TCTCATATTTTTTGCTCACTGGTCTTCTTACTTCTCATAGTCTTCCGGATATAATTTCAA GTTCTGCCTACTTGCTGCTGTTTCTCCAACTTCGGTCATTTTGTGTTCTCCAAGCCTGGA TTCTCATCTGCCAACTGAACACTTCCACATCTCAGAATAAATTGAAACTCTAGATACTTT GAACTGAATTCATGCTCTTTGTCCTCATAACTCATTATTCTGGTATTCTCTGTACTTCTC TGGCCAGAAACCCCCTTTCTTAATCTTTTAGTAATAGCCAGAGTAGTGTCTAATATTGTG GAACTCTTGCTATGTATTGGCCACTTTCATACGCAGCAGCCCTTGCAAGTGTACTTAATT ATGTCCTCAGTTTATGGGTGAGCAGATGTAGATTGAGTGAAGTTAGGTGACTTGCCTAAG AGGTCCAAGTGAAGGTTCAGGCATTAAGACTACAAGGTTTATATTTTTAATGCCACCGTC TTAGTTCAAACCCTCATAATTTCACCTGGAATATCTATTAATTTGCCTTAAATTTCACCT TACTCAGGTCCATTCTCTTTACTGCCACCAGACCTTCCTTTCTCCTTCCTTCCCTCAATT CCTTCCTTCTTTTTTTCTTCCTTCCTTCTTCCTTTTGAGTGAGTAAAAAAGAAAAGACCT ATAGTGTCTCTCTCCTCCTTAAATGTTTCAAAGTCTCCATCTTGCCATCCTAATCAAATC CAGACTCCTTAACCCTTTATGATCAGGTCCCTGAATTCTTGCCCAGGATTTTATCTCACC ATTTATCTAATGATTTCCTTCTCATCACTTCCAACTCTACCAAACTGCTTGAAATCATCA ACAGACCATGCATTCTGGTCTTTGTACCTTTGCATGCACTTCCACCTTTGCCTAGAACTC TCCTTGTACTGGCCAACTCTTAGCATTCTTCAGAACTCAGCCTGTCCTCCCTCTACCTCC ACCATGTTCCTATATTGCTCTGGGCTCTGGGCTTTCCAAAGCTGTTTGGAACAATAACCA AATGTTTTTGGATGGTTATATCAGATGGGTACCAGTGCAGGGAAGTCTCTGGTTTTAAAT CACTTCCCTATGGCATTCACAGCATTCTTCTGCCTTTTTTCCTATTATTCCTTAGTTAAT TACATCTTAAATCAATACGTCCTTACAGAAACAGAAATTCACATCAGTCTCCTCTTTTCT CCTAAAATTTTTTCCAGTTATTTCAGCCACAGAGGTGAATACTTTGATTTATTCTTCTTT CTTTCTCCCTTTCTCTCATATATTTTTATCTGAGAGGAAAGAGACAGCCCCAGTTACTGG TCACATATGCAAACTGACATCTGTATCCAAGAAAAGAAAATGCAAAATGTTTAAAAGTGA GATCAGCATAGTAAACCAATAGCATCCATCTGTAATGTGTTTAGAAATTTTTAGTAGACA CTGTTAAGTCTTCACAATGTTTCCATTAACTTCTGATTTATCACAATGCAATTTGCTTTA CATCCTACAGCTCCATTAAAAAGCAAATAAGAATATACTTCCTATTAGTTTTGTCTTGGT TAATTATAGATATGGCAACATGCTTAGCTCCTACTATATTTTTAATTAAAAGTATCTATG GCGATCAACTAGAATATGGATTACACAGATTTTATCGTTTGACCTGGAAACTAATAACCA TTTGTAAGAGTATTTCTATAGGGAAAAAAAAGGCCTTCCAAGTTTTTAATAGCTGCCTTA CAGACTTTGAGGCATAACCCTTCTAGAAGCTGTGGTCTTCTTACATTTAAATTTGTTAAA GTTTCACTGCTTATTTAAAGAAAATTTAAATTGTTTTCCCTGCATGCTTAGGGAACAATG AAAATGTAATGAAAAATGCATGCATTTTCAAGTGAGGCAGATTGGTGTTTAAATTCCACT GCGACCATTTGTGTTTTCTATGTTAAGCTTCACTTAAGCTTTCTGAACCTCAGTTTCTTG ATCTGTAAAATGAAGATTAAATCCACGTACATTCTGCATCTGCCCCATTAATAAATCATG TCCACTTTATTCTCAAAAGGTATTCAGAATCGTACAATTTTTTTCACCTGCATGCTGCCA TCCTGCTCCTAGTCATCATCACCATTATCTGGATTGCTGCAATGGATTTCTGTTTGGTTG CCTTACTCCTGCCTTTGCCTCCCCTTCAGTCTATTTGCAACTTTGGCAGCCAGAGTATAA ATATTAAAAAGTGAGTCAGTTACACCATTCCTTTGCTCAAAAGTCTGTAAGAGGTTCTCA TTTCACATGGGTAAAAGCCAAAGTCCTCACTATGTCCCACAAGGCCCTACATAATTTGAT TCCTATCCTTCACTATTTCTGACTTCCTAAACACACACACAGGCAGACACACACACACAC ACATACACACACACCTGTGCCTTAGCAGTCTCCCTTGCCCACCTTTTTCCAGCCACATTG TCCTCCTTGTTCTTAAATATTCCAAATATTTCAGGTATGTTCAGGCCCTTGCACTTGCTG ATTCCTTTGCCTAGAATGCATTCTGGATATCCATATGACTTGCTCCCTTGTTTATATCAG TTCTGACTCAAATATTTTCTTCTTGGTAAATCCTTTCCTAGACACGCTTTCTAAAATGGC CAGTGACCCTCTTTCTCACCCTGTGCCCACACCTCATGTGCTCCTTTGCTTTATTTTCTC CTTAGCATTTACCAGTCTCTAAACACTGTATCTTTTATTTACCCTCATTGATCTCCCCTC CTAGAATGTAAGCCTCATGGAGGATGGGAATTTTTGTACTATTTGCTTTTGTTGTACTCC CAGCACTTAGAACCCAGGGCCTGGCACATAGTAGTAGGCACTTGATAACTTTGGTTTAAT GACTTCCTACCTCTCCAATTGTTTCAAAGATTAAGTAAAATAATCCATATAAAGGATCTC CTACGTAGCAGTCACTGACTCTTAAGAAATTTGGCTTTGGTGGGAGTGGGGGCAGATGGA CTTATGTTTAAACATACCTCTTTTGACTACCAGCTCTTGATCTGTGGGCAATTTACCTAG GCTCTCTGAGCCTCAGCTCCCTCCCCACAAAACCCCTTCCATGTATGAAATGGGTTATAA TTAACATCTCACCTTACTATATGGAATAAATAATATAATGTATATAAACTACTTGGCACA GTGCCTGGCATATAATTAACACTCAGTAAGTCGTAACTGTTAATATGCTGATTTTTAAAC ATCTTATCCCATGGAAGTTGAGGAAAGTAGATCGTGGGAAGTAGTGGGATGGACTCGGAG TCCTTGGGTCCTGTCTTCTGTTTAATTCTGCTCTTTGATAGATGTGTGCCTTTGAAAAAA TAACACAACCTTTCTCTGCTTCAACTTCCTGTGAGGAGTACAGTAAATGATGACAACATA ACACCCAGGCAAGAACTGTTTGTCAAAGGGAAACTAGTTTCTCTATGGAAAAACTGTTAT GAGTTTTATTAATAAACTAAGTATGTTGGGTAGAAAAGAAGAGTTCTACCTGCCAATATC AATATGCATTTTAAATTTTAGATAAAATAAAGATAAAAATATTTTATTCTAATTATGGAT GATCTGTGTCTTTCAGGACTGTATGTGCATTCTCCCAAATATCAGCTCTAATGTCATATT TTTCTATAATAGTGTCAGACTAAGAGCCTATGAAAACCTTGTCATTCTCGGGCGGGTGTG TGTGTGTGCGCACGTGCATGCATGTTGGGGTTAGGGTTACCAAATAAAATACAGGACAAC CAGTTAAGTTTGAATTCATTGTAAACAATGAATATGGTTGTTATACAAGTTTTAGCGTAT AAAAGTTTAGTGTAAAACTATTTATTGTTTATGTGAAACATTTTAACTGAGCATGCAGTA CTTTTAGTTGCTTAATCTGACCAACCTACAGGGGGCGCTGTATATGTCTGTATGATACCC TTAGGCTTGTGACACAGGAAATGCGGTCTGATTAGTTCTGCAGCCTTAGTTACAAGGGTC AGCTGTGCTGAAACTAGGTAGGTCTCTGCTGGCTTACTGCCACTCCCAAATGCTGCCCTC TACAACAGCCAATTACAGTGTCACCGAGCCTTCTCATTAGACACAATCTAATGAGAAATG GCAAACGTCAATACTTTGGAATTTTGTTCTTTAGAAACTGTGTGGCAGATGAAGCAATTT TTCAACATTTAGTTTCATAATGAAATGATATCTTTGAAGTTCTGCATATTATATAAGAAT GGGTTGACAATATTTAGACCCATTGAGTGTTAGATATGGAAGGGTCTTCAGATGCCACCT TGGCTACTCTTTTTATGCTGATAAGGCGACACTCAGAGAGTTCAACAGATTTGTGCAGGA CTACATTCTGGCTTGGATGAGATTTTGGCCCTCTGTCTTCAGGCTCCACTGGTTTTCCCT ACAGTGTTTCCCCTATGGTGCTCCCTATCTAATCCCTGCCATGACATTAGAATACACATT CACGTAGTGACAGAGTAGGATCCATTTTTCTTTCTCTGTGTGGCACCTTGCCCAGGATCA TTTGGATGTATGGATATAATTGATAATCTGGTGCACCATGGTGTGTAAACATTGCCATCC ACCTGGCCACTGTTATTTTAAATCATAAGCTCATCTCTATTCACATAATTTTCTATGCAT TAAATTGGGTCACTTAATGTGATTATACAAAAATAATGATCCTATTCCCAGGCCCTTATG ATAATGCACATTTTTTTCCTATTCTTTGAGGTGCAATGTCAAAGGTAGATTCTAGTGTAA CTTTCATCACTACAGCTTATTTAGATATTCTGCATTTTCAATATTTCAGTAAAATTTAAA ATGTTCTTGCTTCAGAACAAATTCTAAATAATGTGACACCAACGGGACAATTGGAAATTT AAACAGTGACTTTAACGGTGTTGGAAAAGAATGATGTTTCATTCTTTAGGTGTGATAATG GTGTTGTAGTTACATTTAGAGACACATACTGATATACTTATGGATGTGCTCTTGGCTTGA CTTCAAAATTATATTGTGGAAGGAGACAGGATTAAGTAGGGAATGGATCAAACAAGATTA CTATTGAGATAATTACTGAAGGTGGATAGTGAGTACATGACAGTTTCATTATACTATGCT GTCTACTTTTGTATATGCTTGAAATTTTCCAGAACAGTAAAAACTGTATCCTTATCTCCA AACTCTAGTCTGCTTATACAAAGACAAAATAAAATTACATCACAGGAAATCAAAGATTTT AATGCCCATCTTTAGTGGGGAGAAATAATATTTGTCCAAAAGTTCAGTACTTGTGTGTCT GCTTCTTTTGTTCCCCTTCGTATTTTTGTGTTTTGGGGAGAGTAAACATGTAAGAGAAAG AACTTAGAACTGGGGACTCAGGGAGTCTAGATTCTAGCAAGTTTCTGCCTTTTGTTAGTT GTGTGACCTCAGGCAAGATACTTAATCTCTTTGGGTCTCAGTTTTCTCATTATGTAAAAT GAGAACATTGCACTGTGTGGTTTCATAGGGCGTTTGGCTCTAAAATTGTTTGACTTGATA TCACACGCAGGCTTTCCAAATCCCCTGCAAACTTGGCTCATGGAGTGTTTAGTCCTGTAT TCTGTCTCTATTAATGGAGCAACGGGCTATATTCTGGGGACAACTGATTTTGACTTAAAG ATATTAGGAATGAGACACCGAAATATTTTATGCTTCCCATGAATCTCCTGTGCAGCAATT TATTATTTAGTTTCTTCTGAAATTGCTATTTTTTTTTTGAAATTTTCTAGTCAACAATGA GTTACAGAAATTATTTCTCACTTTGAAAAGTTGAAATTTCTTGATATAGTGCTAAAATAA ACTCAAGATTTTAAAAGTGCACCCTTCTTTTAGTAGGCCAAGGTCTTCTTAATAATACCA TATATTCTATATATCATTTTATGATTTTATTACCTTCAGTTATCTCCCCAGTTTTCTTAA TTCTTTTATGTATTCTCATGTAGCCAGATCTCTTCACCAATTTTATTACTTCTTTTTTTT TTCTATTCCTAATTCTGGAATTTGGCACACATTACATATGTTGTATTTAGGCCATAAAAA AAATGCTATAGTGAGACTTCTGAATATGTGAAGCACAACCTTAGCTCACTGTAGATCTAT ATCTTTGTAACTTCTACACGAGTATTAAATTGTATTGCAGTCCTATAATCATTGCAAAAC ATTTGCTTATTAAAAATATGTACTGGATACTACTTTATAGTAATACTAAGTATTATCTCA ATGTCACATCAAAATTCATCCATTCAACAAATGTTTAATGAATGTCTTCTAGATGTGTTA ATTCTGAAAAGCGATTTCACAGGAAAGAAGGCTTAGAAGAAATTACCAGAGGACACAGAT TTCCAATTTTAAACTGATTTATTCATCAGAAAATGTTACTAAGTGACACTTACTTATTCA TACACACAGTCCTCCTCTCGCGTAGATACTTCAAAATTACCATAATTAATTCAGAGACCC AACTCTGGTCCTCTTAAAGTAAAGTGACTATTTCAGTGGAAGCTATAATGGAATATCCCT AAGAAATCCATTGTCATCCTTAAAAAATACAAATCCTCTTGGCTTACTCAATGTCTTTGT GATAATCCTTTTTATCAATCAGTAACCTTCTGGACCAGGATTTGTTTGTTTAGTTTCTAT GAAGCAGTGATGCTTTTATCTAGAATCTTTCAGCACCAGTTTTTGATCTTCATGGAATCA TGGGGTTTTCTCTCAATTTGTTAGAAGTACTAGACATGACAAGTACTATGATTTGTTCCT TCTTTAGCCAGATATGTACTCTAGTGACAATGCCAGATTCTTGGATACTGCTTTTGTAAC CATTCCTTTCTTTCACCATAATCTCTGACTGATACATTAGGGTGGGCTCTGTGGTTAGCT ACTAATATTAACATTCATTCATTTAGTCATTCATAAACATTCTTTTGGTCATTCACTCTT TGTTAGGTAAGTACAAGAGTGGCAAAGATAATCCTGGCACCCTCCATTTCAAAATAACAT GTTTCTTGTTATATAACATTTCTTGTTAATAACAAAATAACATATTAGTGATACTTGGTA GCATATCAACTAATCATATGGTCTGTGGTTGAACTTAAACAGTCTGTGTTCTCTTGATCA CAGTGTCTTGAGTTTCTTTTTGAGTCTTTCATAATGTTTTCATGAAGATTCCCATCAGGC TGCAGGGGAACATTAGGGAACATGTGTCCAGGGGAAAGGATTAACCAAATCATTCTCCCT TCTTGGCCAACCCTTTGGAGATTTTCATTGTTGTTGTTTCACCGTCCTTTTAATACTCTT TCATGAGGAATACTTCAAAGCCTTTTTAAAATGAAAAAAATTAGGGTCACTGGTTGCCCT TTGATCATATAGTTCTCTCATTTTCACATAACTGCTTTATGTAAAAGAGGGCTTGATTTT CTATTTGAAAAATCAATTTCCTCCCTGAGCCCCTCCTATTACTCTCCATAGTGACTTTTT ATTCATTCATTCAACAAATATTTACCAAATGCTTATTGTGTGTTAGCACTGCATAGATAA AAAACTCAGTAAGTATATTTTTCTTAGGAAAGCTATGACTCAGTTCTTTTCTCTGACCAG CATTATTTTTGTTATTGATATCCCTCCCTTGAATTGTGTTTGCTTCTTATACTGAACATT TACTGTGTTTGTTTCTGTTTGCCCTAGCATTCTAAGCAACACAACGCAATTTTGGGTACT GTAAATTTTTTCAATTTTTTTAAAAATTAAAACTGAAGGAAATAATTCAAATATTCTTCA AGCCATATCTATATTATCCTCAAAAACTTGTACCTTTATTTTTTTAACATTATCCTCTGA ATGTATAGTATTAAACTATTCCCTAATTCTCACAGATAATGATGGAGTAAACTTTACTTC TTGGGCAACTATCACTTTTAGGCATGGAGACCAGGGAACTTTGCCTTCCTTTTGTGTATT TGTTCCCAGAATCATCTTCCTAAAGTCCCTGAATTTGTCTCCTGACCACATTTTAAATTG TCCTCAATCTTCCAATCTGAATCTCGCCCTACTCTCGTGCCAACTTGTTAAATAGCCCTT CAGTTCTCACTTGTAATCCTCATATAATTTTCCCTCATTGTGTTACAAGGATTTCTTCTT CATTTCCCTTTTGTCTTATGAATTCCTGTGTTTGGGGAGTGGGTGGTCACTTCTGTGACA AAGGAGAGAAAAGATTGCCAAAGATGTTATCTCTTGTGCCTTTTTTATTTCCTTTGCTCC ACACTCTCCATTCTGTATTCTTGATCACATATTGTAGATGATTAGGTTGGGAGGAGAAAG AAAATCAGGTGCATATTTCACATGTCAATTTGCCTAGAACGTATCAAACCTCTTAACTGG TCTTCCAGGCTGTAATTTCTACCCTAGGCAGGCAATTCAGCAGACAGATAACATGTAACC TGTTAAAATGCAATTGTAGTTATTCACACACAGATATTTCTTCAGGCACATTAAATAATG CCTGTTCCCATTTCCTTAACATTCCCTTTATTTACAACTATCCTGATATTCAGTTCATTC TTTAAGGAAGAACTCAAATGCTACTTACTCCATGAAATGATCCTTCACATTTGTAAGAGA ATTAATTCCTCTCTCCTCTGTTCTATAGTTTTACTGGATTATTCTGTTATAATTATATAA TGTTCCTCTTTATCCCTAATAGTTCTTTTGGCTTTAAATTTTATTTTGTCTTATATTAAT ATTGCTATAGCTTTATTTTTTGTTTTATATTTTCTTTAGTATTTTACTAGAAGAGTTTTT AAAAAACCTTTTTATTGTTTTGCCTTTTCATGTAATTTTGCTTTAGACATGTCTCATAAC TGGACTTCAAAAAAAATCCAATCTGATAGAATTTAATCCATTTATATTTATTGTTATTCT TGGCTGACTTGTACTTTTTCCTATTTTCAAATCTCAGTTTCAACCTTTACTAACTTTGTG ATTTGGACTATTTGTTTAACTTATATATATCTTACTTTTGTCATCTGGAAAATGTTGGTT ATAATAGTATCTACCTAATTGTAAAGAATCAGTCAGTTAATGTACGTAAAATACTTTAAA TGGTGCATAGCATTTAGCTATGTGATAGCACTGTGTAATAGCACAGTGAATGCTATTACT ACCACCACTGCCAGTACTACTACTACTATTTTACCTTGTTTTCTAAGACCTTATTTATTT TATTTCTTTGTTTGCTTTTTATAATTTCCTGACTCACTGTAGAAAAACTTTTCTACTCTT TTTTCCCTTTCTACTGGATTGAAACTATAAATTTTAGTCCACTGTTTTATTGGTTACAAT TATTTTTGTTTATTTTTAAATTTACTTACAGTAGCATTCATCCATTTGGTGTACAATTCT ATGAGTTGCAATGCATGCACAGATTCTTGTAACTATCACCACAATCAGAATTCTAAACAA TTCCAAATGCACTATTTTCTCCTGCTGACCTCCGTAGTCAGACCTCCTACTACCCCTAAA ATCTGGCAATCACTGATCTGTTTTCTGTCTCAAAAGTTTTCCCTTTTTCATCTAAATGTA ATAATAGAGTATGTAATATTTTGAGATTGTGTTCTTTTACCTAGAAAAATGTCTTTGAGA TGAATCTATATGGAGATCTATTACATTTTAATGATAAAAATTTTTACCAAAATTTAAAAT TATTTAATATATCCACACTTTTTAAATGAAAAGATCTTAGCTATATGTACACACACTGAC CCTCCATTCTTCTGTTTTTCTTCTTATTGTTGTCTAGAATTTTAATTCTACTTTTAAAAA CATAATGTTTCTTTGTTTTTCAGGTAATTGAATGTAGCAAGAATGTTCTTTAATTCTTTC AGTCACTCATTTTTTTTTCATCTTTTGACCCCTTTGTATTTACTATTTTTCTTACTGATG CACATTCCTTAATAGTTTTTTCATCAAGGGTCTGTGAGTAGTAATTTCTCTTACTCTTTG TCTGAAAATGTCTTTTTTTTTGCTGTTTCTTCAGTGTCAAATGATAGTATACCTTGAGAT AGAATTCCAGATTGACAGTTTTCTTTCCATTTTCAGAAGATATTTTCTATTGTTTCCTAG TCATATTGCTACTAATGAAAATTTATTGCCAATTTTGTCAATTTTATTTTTTGTAGATAA GCAGTTATTCTTTCTGGGAAGTTTATATATATGAATATATAGTTATATGTATAGTTATTC TTATAGAGTTATTCATATATATAGTTACTGTGTGTGTGTGTGTGTATATATATACACATA TATATAGCTATTCTTCATTCAGTTTCACTAAATTCTACTGAAGTATTGTTTTATGTTTGG TTTTTCAACTTGACCTTTGTTTTATACTTTTAATCTAAGAATATCTATTTTTATTCAGAC TTGGAATTTTTTATCTATTCCCTTTACTCTATACTTTGAATTTTTTTAAGTATACTTGAG AGTCTTAACTGGCATTTTATGTCTCTTAATTGCTTTTTTATGTATTTTAAAATATCTTTA TCTTTTTGCATTGCATTTTAGGTGAATTTATCAATACTACATTTCAGTTCACTAATTCTT ATCATTGACTCTTACTAGTTTAAAGTTTATTCCACTAACTTTATTTTAAAAAATTAAACC TTTATTTGTAATATTCAAGATTTCTAATCTACTTACTCTTCTTAGCTATTTGTATTTCAT AGTATATGGTTCTATTTTTTTTCCATATTATTGCTTCTCTGTATCTTTTTGAAAATCCTT AAGGTTTTTATACTGAAGTTGTTACCAAGATGTTTCTGTTTTGTTTTGTTTTGTTTTTCC CCCTCTGGAATACATTTATTTCCCACTTGTTGATTTCTTTGATTACAACTTTTAGCATTA AATTTTCTTTACTGTTTTGGAGTTTTGGTTTGATATAGCAGATTAGTTGATGCTATTTCC GTTGAGTCACGACTGTGAATCCCTGTCTCTTCTTTAATTTGATGGAATTTCTAACTATTT TTTAACAACAGACAATGGTGGAACTGACACTGCATCAGTTTCTGGATACTTCTTATCTCT TGTATCAGTCACTTTAGAGCCTTAAACTGAGACTTGAGAAGTTTCACTACCATGTGAATG ACCACATGGAAAGACCCTGAGACTTCACAGAGAGGGAGTGGGGCCTAGCTGATCCCAACC TTCCAGCCATCTCTGCCAGGGAACCAGGCATGTGAGCGAATCTGTCTCTGACCCTTCATA TCACCCCAGCCACCATCTGAATACAATCAAGGATAATAATTGATACCAGGTGAAGCAGAA GAATCACTCAGCTGAAACCTGTTGAAATTCCTGATCCACAAAATTATAAGATAGAATGAA ATGGTAATTGTTTTAAGCCATTAAAGTTTTAGGGTGTTTTGTTACTTAGCAACAGACAAC AGAAATGGGGTTTTATCTTGAATCTGACTGTTTCCCTGCCTCCTACCCGCACCCCTGCAA TCTCTGTACATACCCTTCTTGACTACTGGTTTTGGGATGCTTCACTAAATTTCCCCATTC CTCAGTCCAGAACTAAGGCTTAGAGCTCCTATTGAGAGCAGGTGATACGGGAGTTACTGC AGATTGGAGTCACTGAGCTAAAAGCATCTTGGTCCAGTTCCTCACTTACATGAAGCACCT CCACTATCATCCCTTCCCTCTGCCAGAGCCTCAGGAAATCTTTAGAGTGAGAACCTGGAA GTAAAGCACATGAAAATGTGGAGCTCCACTAGGACTTTGACCCCAGAAGTGTCTCACTCT CATTTAATTCACACTCAACCTCCAAAAATTCACACTCAACCTCCAAATTCAAGCTACTTC GAAGTTTCAACCTCCAAAAATTCAATAATCCATTTTAAATGTTTCTATGAGTCTATGGCT TCAGAGTTTATAGCTTCAGAGACTTCTGCTCCAGGTATGTAGATCTAGGCTGTGTCTCTT GGATATGCCTGTCTCCCCAAATTTCAGGGTGATGGTTTGCTATACAGCCTCAGTTCTCTG ATGGGTCCAAGAAAAGTCAGTGATTTTCAACTTATCCAGCGTTTCCTTGTAAGGATGACA GTGATGACTTCCAAGTACCTTGCCTGTCCGAGCTCAAGCCAGAAATTAGTTATGGCTTTT TTATTTTAAATTTTCATAATTTTTATAAGTATATATTATTGTTAAAAGTTTGGACCAGGA TGCAGAACCTCCAAGTGTGAAATCACAATTCCGCCTCTACCACAAATCCTGAATATTTTC TTTACAATTCTTTTTCAGTGTATAAAGCAGACTTTTTTTTTAAAAAAAACTATATAATCC GTCTAACATACACGCAGAAATGTGCCCCATCCTAAGTATACAGAACAATGAATTTTCACA AACTGAAAGTCACCAGTACAACTGGCACCCAGGTAAAGAATCAGAACATTACCACACTCC CAGGAACACCTCTCATGCCCTCTTCAACTGCCCTTTCAACTTTACTAATTGCCCCCACTC CCAAAAGACAACTACTATTTTGACTTCTTATAGCATATGCTAGTTTGGCTTGTTTTTGAA CTTATACGTGGAATTGTACAGTATGTGCTCTTTCGTATCTGACTTGTTGGGTTTAATGTT AGGTTTTAAAATTAATCTGCATTATTGTATATAGTTCATTCTCATTGCTCACTGTGACAA TTTATCTGTCCATTCTAAAGTGTATGAAGATTTTCATAGTTTCCAGGGCTGCTGAAACTT TCTAGTACATATTTTTGATGAATATATATGTGTGTTTCTATTAGGTGTATACCTTGGAGA AGTCTAATTGCTGGGTCATAATGTATGCATACTTTCAGCTTTCGTGGACACTGAAAAAAA AGTAATTTTCTGCATGGCTGTCCCTGTCCTCCTTCACTCCCTCATTTCCCTATCCCATCA ACACTACCCAGAATGTATGAAATTTCTAGCTGCCCCATATCCTCATGAACATTTGATATT TTGCGTCTTTTTCTCTTTTGCTGTTTCTAAAGTGTATAGTGGTGTTTCACTGTGGTTTTA ATTTTATTTTCCCTATGGGTAATAATGTTGAGCATCTTTTTACGTTTACTGGCCCTTTGA GCATGCCATCCATTATGATGGACTTTTAGTCAAGTCTATCTTTCTAGCTAGACTGGGAGG TCTTTCTAGGCAGGGTTCTTATCATTACCTTTGCATCTCTCAAAATCTGCCATGATGTTC TTCTCATGTGCCTTTCACCCAGTGTTACGGAGATGTCTGCTTAACTGAATGAACATATAA AACATATAGGGTCCACTTTTATATCCCAAGCTGCACTTAGGAGCCACCACAAGGATTATT CCTGAAAAATCAAATATGTAAGTTTTAGATTTTACAAATTTAAAAGATCTTAAGTAAATA TTTATTCAGTGCCTAGTATATATTGGGTTTTGTGTGAAGCTGTGTTGGTGGAGGGCTTAT GAGTGAATCAGAGACAATTCTTTTACTCATGGAGCATTTAGACCATGGGCCGGCCTAGAT TAAGTGCTGGTTTTGAACGAGCCCGCCTTTAATATAAGACCTCGATGTATATTCCGCCAT CTCGCTGGTGCAGTTGGATGGGAAGAAGCTGATGTATAGTACTTTAAGTATATGAACATG GAAGCTACTTTGAAATTTCATCTTGTGAGATTTCTGCCTAGTAATTTTCTAAAAGGAAAA AAAATTAAGATTTTTCACTGATACTTTTTTCAAAAGTGGTGTGAAGTGTGTTTCGGAGAT GAAAACATCCAATTACTTGGTTCCTAATTTCTCAGCTATCCTAGACAGTCTCAAGTGTCA CTGTGGGTTTTGTTAAAGAAATTCTCTTCCCAGTCTGACACAGCTTTGTTATCCTCTATA ATAGCAGAGCTGTGACCTCCACCCTGAGGAAACACTCTTCCTGGCACTAACTATGACACC TAGAGATTTCATTTTGCCTCAAACACTTTCCTATTTTCCTCCCATAACTGTGAAAAACTC CTCTGTGGAATCAGGTACTTTATGCAGTAGGTACACACACTGAAAAAATGACTTTCAGAC TGTGGACAGCCACCTCCCAAAGGAAAAATACTGTAGCTGTGAAGGTGATGGCACAAAGCC AGTTTCTCCATGGTGCTTAGTGAGAGATCCCATTGTGTACTTATTTGCTTTTTTAAAGGT ATCTTCATTCTGCTTTTCTCTTCTAATCAACTTCTGCTACAGAAAGTAAAGAGAAAAATG AACCCTTCCATGGAGAAACTACATTATGTTTAGTACCTAAGGTATAAAGGGTGGCTGTTG TTTTCTTGTTTTCATCATATTCAAAATGATTCAAAACTTTTCACCTATTGAAGATGAGGT GACATATGTATCTCAACAGTTATGATGATTCACGTGCCCATTTCTTCACTCTGTGCTCTG TGAAGTGATAAGAGATACTTTCGTAGCTCATGTTTCATGGAACTTGTGCCTGTAAACTAT TTTAGGATTTCTGGCCTAATGCACTTTCCCTCAATGATAGTTAAAATTCCGTGGGAAGGT TTCCACATGCCATGGACTTAAACATGTCCTAGCAGCCACAGCATGGCAGCTGAACTTTCT TCTCCTTCCACCCTGTCTCTGGTTCCAGTGACTCGCTACCAGGGACTCGTACTCACAGAA GAATGTTTTCTACAGGGAACCATTGTCCCTGTCCCCCTCCTCTTCATCATGATCGTGGAA ACAGAGCTGATGCTGAAGTGCTCAAGGCGTCGAAGGCATGTGTGTTCCCTTGAGACACCA GCACATTAAGTTCATATCTGATTCATGCAGAAATGGAGGGAGGGTGGGCATGGTGGCTCA TGCCTGTAATCCCAGCACTTTGAGAGGCCAAGACGGGCTGATCACCAGAGGCTGGGAGTT TGAGACCAGCCTGACCAACATGGAGAAACCCCCGTCTCTACTAAAAATACAAAATTAGCT GGGTGTGGTGGCGCAGGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCAC TTGAACCTGGAAGGCGGAGGTTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCTGG GCAACAAGAGCCAAACATCATCTCAAAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAAAG AAATGGAGGGAATACTTCTTTGCTTGCTTCTCTGTTAATCTTTTTCTTTATCAAATATGT CCCCAAGCAACACACCTACGCCCCATGTCTCACTGAGTTTCTAATGAAGGAACTCTTTCG TTTTCCATCTGTTGTCCCTGTCCCCAGAGGCCTGGCAGGGAGAAATATGCAAGTGACCAG CACCACACTGCACTTAGAATCATCTCCCACTTCCAGTGACCAAGGCATTGTCCTTGGGTT AGGCATGTATCCCCTACTCTCCCTTCCCTTAGCTGGAGTCCCTCCCAGAGGGTGCCTCAG TTTCTCAGGAGAGTGGTCTTTTGTGGGGGCTTACCTTCCAGTTCAGCTGACTGAAATGTC TACCTTCAACCACGCTCACAGCTTCCATATGCCTTTTTTCTGGGACTTCACCACCACTAC TGCCCTCAAAGCCCTGACCACATGCCACAGTATTTATTTGTGAGATTACTTGTCTCGTTG GTAAATACAGCTAGTTAGAAAACATCCTTAGTTATCCATTATCCAAACAAATACAGCTCA AGTTTTGTATTTTGTGTTCATGAGCTTCTTTATGTGGTTTCTGAGATTCCAGATTCCTTT GATACTTTTTCAAACCTTCTGCTTGCCTTTTTTTTCTGAGCTGCATTTTCTATTTCCTTA CCTCGTTTAACTGCAAATACCCCATAGCATTTGAGTCCTTGCTTTTCTACTCTGTCCTGA CCTCATCTGAAACCTCCTTACCTATTGCTTTGATTACCACAATGTGGTAATTACACTATG TGGATCTCTTTTGATCAGTCACAGATTTGACTTTTTTTGGTCTATTCAAGTAATGTTTTT CCAGACACCACTATGTGCCAAGAGCTGTAGTCATGATGAAGATGCCTCAAAATATACTCT TAAGGAAGGCAGAAAAGGAAACAGATGATGAGATAGTGGCGACTTAAGACAGTCGTATGA AAAAGGGGTGAAAGGAGCACCTATGGGAGATGACAGCCTTAACAGGTAAGGTAAGAGAAG TCTTCTTGCATTGGCTACTGCTTATCCTTGGCTCAGCTCTCAGTTATTCATCACCTTCTC TCAGTAATCAGTCCCTGACATGTGACCTTGATTGAGACAATAATTGCGCCTCATCCTCCC TCCCACATTAATAGGTCCAGGGATAGACATATGACCTTAGTTGGGCCAATTGAAGGTATT CCCCTAGAATTTTCCTAAGAATTCTCTATCCTCTTTCATATAGTGGCAGTTGCCTGCAAC TGTGTTTGCAAAAAGCCTGTTTGTACAAGGAAGAAGTTAAGTTATTATATTGTGGGAGTA GGGAAGGGAGGCAGGATCCACAAAGAGACCTGGCAACAGGTGTCCCTAGATCAGGCCATG CCTGAAGTCAGGTCCATCACCGTTCTTTCTGTCAATACAGACTTCTTTTTTTTTTTTTTT TCTGTTTAAGTTGCTCCAGGTTTTGTTTAAATTGGATGGTTCAGGATTTCGGTTCAGGAT TGCAACTAAAAGAGATGCAATTTAAATGTTCTCTAAAGGAGGTGATGCCAGAGTTGAGTG CTGAAGAAGGAGAGGAGCATCACAGAAAGGGGATGCACTTTGAGCAAAGGCTGCAATGAG ATGGAAACGTGAACAGTGAGGACATTAACGGAGGGGGAGAGGACACTGCTCAAGGATATT GGAGAATCATTTCCACTGGAGACCAAGCAGAGGAGTTTGGGGTTTTACCCTGAACACAAT AATAAAATAATGAATTTTAGGAAGATAGCTTTGGTACCCCAAACTTTTTTACTCAAGTTC ATTTGGAGAATGACTTGGAATGGAACAAAAACAAAGCAAGGAGAAAATTTAAACAACTCC TCTGTTACTCCAGTCAACAATGATAAAGACTTGAATTAAGGCAGTGGTCCGGAGAACAGA GTAAAATGGTGGCTTTAAAGGAGAATAAAGAGATGAAACTGCCAGGGCAGACCTTGGGCC ACTCGAGGATGAAGGAGCCGTTCCACTGAGATGGGGGACATCAGAGGCAGAGAAGGTCTG GAGGGAAGTTGAGGCATTTGCCCATTGTGCCTGGCAGCTCAGGCTATCCTCAAGCTATCC AAGTCACCGCCAGATGAATTTTAATAAAATACTCTTTTCAATGTATTTCTTCATCTGTGA AAAGATTGTTGAGGGAGGATAAGTTTAGATTAGTTGATCTTTAAGATTACTTCAGGTGAT TAAAAAAATTGATTATGTGTCACTGCCAAGGAATCTACACAAAGATTCAAATTCTAATCT CTCACCCTAGATTCTAAACCTTCCATTTTCATTTGGCCTCCCTGTGCCTCTTTAATCTTA TTTACAGATGCTTTCCATGCCACACTCTCTTCTCTAGACAGAGCAGTTCCTTCCATGTTC CTGCAGATGCCGAGTTTATAAGACGCTCCTGTACAGAATCCTGTTTTCCATTTCTTTCTT AGCAATTGTCTTAGCTTGGCTAGTTCTCCATTCTATTGAGATGCCTTCCTTCTCCATACT CTGCTCTGTCCTGGGGCCCTTATATGTCGTCTCTGAACGTGCACTGTACTCAACTCCTAT GTAATACAATCAGTCATACATATTCTCTGTAATTTAGAACTCTAATTATTTCATATGTGT TGGTTTGCTTTCTAAACCTAGTGCTTCTTAAGGGTCTTTGGTGTCTGGAACAGTGTTGGG TGAATTGTAGAAGCATCATATAAGTCAGTTATACATGTTCTTCACGTCTCCTGGAATCTT TCTCCACCTCTACTTTTTCACAAAATTCCATTCATACATCCTATAAGATGCAGTTCAAAG TTTGTCTCATCTGTGAAGCTAAGCCCCAGACTGAAATGAATTATTTACTCTTATCTTCAT ACATATGTAATATATAATATATATTTGAATATTTGTGCATATTTCAGTCATAATATTTTT CAAATAATATAGAGCAGCATTTCCAATAATACCTATAAGAGGCAGATTTATTTTAATATC CCTAAGCCACCACACCTAGTACAATGATTACTTGACCCTTTGAAATATTTTTGCAGGGAA GAGGATTTCATATTTGTATCCATGAAGTCCCATTAGCACATTGCAGCATGAGGACAAGGT TGAGCTCATCCAGGGAATAAGCCCATCAGCTGACAGAAAGCAGGTGATGAGATCTCTCAC CAGATTAAAAAGGGAAGGGCAGCAACTCATTAGGAAACACAGAGATGTCTGCTTAATTAC TTGAAAAATGTCTGAGCCAGTACATTTTATGACACCTGGAGGGTATAAACATGCCCATAA ATTTAATTAATTTTCTTTGTTCTTTCATTGCACCTGTATGGCATAAAGGAAAGGAAGTCT AATGAAAGTACAATCAAGCACTTCTGCCAGACTTCCACAGTTCATTTGGGCAATATTCAG AAAATGAAATACTGAATTTCTTATCAGTTTATGGGGAGAAATGTATTTGGAAAAATGCAG CCCAGCGGTGAAGTTATTCACATGTCAAACTCTGATCAATGGCTTCTTCAGCTTTATTTC CAAAAAGAGCTTAAATCTCTTTATAGATGTATTAAAACATTTAATACTCATAAATCTCTA AGGAGAAAATCAGAACTAGATATTTTTTTCTTGGGGGAAAGCATTATATGAGAACTAGAA GGTGTAGGGGAGTTGGTCAGAACTATAGAGCAAGTAGCCCCATTTGCTCTCTGTTGTAGT AGCATCGCCCACACTTTTGTTAAAAATCTTTAAATCTATGATATTGCTATTTTTATCAAA TGAAAATGTAATAGTAATGAGTATGCTTGAATATCCATTGCAATATTACATCATTTAATG AGTGCTCACTCTTTGCCAGAGACTGTACCAGTACTTTACATATCTGATCTTGAATCCTCA TAACAGCACTGCAGATAGTAATAACCCATTTGAAATGACTCCCGGAAAGATTACAGGTCT TATCCAAGGCAACATAGCTAGTAAGTTTTGAAAGTAGGACTCAAATCCAGGTCCTTTTGG CTCCAAAATCTGTGCCCATTTAATTTTGTTATATGAACAGTAATGTCAAGCCATTTTTCT CCTTGTTAATTCAGTGTCACTGAACATATGAAAAGTTTATAGACACTTCTTGTTTTCTTA AAATAATTTTGACATCATTGAGCTTTGAGTAGTGAATTATTCATTGGAGCTTCTGGACAT AGCCCGAACAATCTGCCCTCCCAAGAACTTACTGAAGAAAACTTCAACTGTGTATGACTT CAATCCAAAATATACTTGTCTGCCTCCAGTTTTTCCTATAGATACCAGGAAGGGGTGTCT TACTCAGTGTAGGAGAAAGGGAAGGAAACTATCGCGTATTGAGCTCCAACTTTGTGCTCA GTATATATCCAGCCTTTTGCATGTATTAACTCACTTGATATGAGTTATGTGGGGAGAAAG GTGACCATTCAGAAGCCTGTTACCAAGTAATTCTCACTGGGAACATCCCAGGGCAATGCT GCCAATTCCCTTGGCATTCTACTTTTAGAAGAGTGGTGGTGAATGCTAAGATTTATAGTC GAACATATCCTGAGGTGATTTGAAAACTGCTACTAGATAAAAGTGAAATGAAATATTTTC ATTTTAGCTGTTAAATTTCTCATTTTGTCATGAAATACCATAGTTAATGCTGTTTTCAGT TGTAATCTCTTGTAAACTCATTGACTGTTAATGTTTAGTGGGCCCATAAACTAATTTGAA TTGATCTGATTTTGCACAATCAAGCCCGTTACACTTGTTTCAATTTTTTGCATCACAGCT TTAACATCTGGAAGCTATGAAAAGCACAACAGCCTGTCTAAAGAGACTGTCACAAGAAAT CGTGTTAAAGGACATATTATTAAGACCTGGCTAACCATTGGCACTAACGCTCCTGCCACG CTCTCTCCGCTTCTGTATCCAGCATTACAGATGGGAGTAGACAAGAGGGGTGGAGCATGC GTGGAAGGCTGCTCCGCAAGCCTTAGTTGGGAAATGCATTTCCCAAAACAGATTATTTTC TAGGTACCTACTAAGCTCCCCAACCCATTCCCCCTCCCATTGCCCTCTCTGATTGGTTTA TCCCAAGCAGTGATTAGTTCCTCAGTGATACTTTGGACTTAATCAGGGCTAGCTGACATA TTCCTGGGGCAGAGTCAGAAATACTTTTGTATTCAAGATTCTGAACCATTATGTGTGTAT CAGTATGGCTATATGTCTTTGTTCTTTCCTAATCATTATTCTTTGAAGAAGCTAATAAAC AAATAAATCTGCCTTTGAAAGTGCAACATGTTAAAAAGAGTCCGCCTGTGATTATTTTCC AGACGTAGCAAGGGAGAATTAAGGCACCAAATTCATTCACATTTTTGCATGCATTCTTAA CCTTGATTTAGATTAATATATATTTGTGCCTTTTGCCGTTATATTTTATTGCTTTTTGCA TTTTTATTGGTTTGTAGGTTTTAAAATATATTTTGGATACAATCCTTCATCAGACATATG TATGAAAATATCTTCTCCTAATTTTTAGTTTTTCTTTTCACTCTCCCATTGATAGTTTTA ATAAATATAAGTTCTTAATTTTAATGAAGTAAAATTTATCAATCTTTTATGATCGTTGCT TTTTAAATTTTTAATGTATTTATTTTTTATTTCAAGATTTTTGGTAAACAGGTGATGTTT GGTTACATGAATAAGTTCTTTAGTGGTGATTTGTGAGATTTGGTGCACCCATCATCTGAG CAGTGAACCTGTACCCAATGTGTAATCTTTTATCCCTCACCCCTTCCCATACTTTCCCCC GAGTCCCCAAAGTCCATTGTATCATTCTTATACCTTTGTGTCCTCATAGCTTAGCTCTCA CTTACGATTGAGAAGATACGATGTTTGATTTTCCATTCCTGAGTTGCTTCACTTAGAATA ATGGTCTCCAATTCCATCCAGGTTGCTGCAAATGTTATTGTTTCATTCCTTTTTATGGCT GAGTAGTATTCCATGGTATGTATATAAGCCACATTTTCTTTATCCACTCATTGATTGATG GGCATTTGGGCTGGTTGCATATTTTTGCAGATGCAAATTATGCCGCTATAAATATGCACG TGCAAGTATCTTTTTCATGTAATGACTTCTTTTCCTCTGGGTGGATACCCAGGATATCTA CCTTGATCCATTTGCTGGATGAAATGGTAGATCTGTTTTTAGTTCTTTAAGGAATCTTCA CACTGTTTGTCATAGTGGTTGTACTAGTTTACATTCCCACCAGCAGCGTAAAAGTGTTTC CTTTTCACCACATCCATGCCATCATTTTTTTTTTTTCAATTTTCTGATTATGGCCATTCT TGCAGGAGTGAGGTGGTATCACATTGTGGTTTGATTTACATTTCTCTCATCATTAGTGAT GTTGAGCATTGTTTCATATTTTTTTTGGCCATTTGTATATATTTTTTTGATAATTGTCTA TTTTGTCCTTAGCCCACTTTTTGATGGGATTGTTTGTTTTTTCTTGATTTTTTGTTTGAG TTCCTTGTAGATTCTGGATATTAGTCCTTTGTCTGATGTATAAATTGTGAAGATTTTCTC CCACTCTGTGGGTTGTCTGTTTACTCTGATGATTATTTATTTTGCTGTGCAGAAGCTTTT TAGTTTAACTAATTATCATCTATATATCTTTATTTTGGTGCATTAGCTTTTAGATTCTTG GTCATGAAGTCATTGCCTGAGCCAATGTCGAGAAGTGTTTTTCCAAAGTTATCTTCTAGA ATTTGTATGGTTTCAGGTCTTAGATTTATTTAAGTATTTGATCCATCTTGAGTTGATTTT TATATAAGGTGAGAGATGAGGATCCAGTTTCATTTTTCTACATGTGGCTTGCCAATTATC CCAGCACCTTTTGTTGAATAGGGTGTCCTTCCCCCACTTTGTTTTTGTTTGTCTTGTCAA AGATCAGTTGACTGTAAGTGTTTGTCTTTATTTTTGGGTTCTCTATTCTGTTACATTGGT CTATGTGCCTGTTTTTATACCAGTACCATGCTGTTTTGATGACTATGGCCTTATAGCATA GTTTGAAGTCAGGTAATGTAATGCCTCCAGATTTGTTTTTTTTGCTTAGTCTCGCTTTGG CCATGCAGGCTTTTGTTGTTGTTGTTGTTCCATATGAATTTTGAGATTTGTTTTCTAGTT CTGTGAAGAATGATGGTGATATTTTGATGAGAATTGCAAGGAATTTTAGGATTGCTTTTG GCAGTGTGGTCATTTTCACAATATTGATTGTACCCATCGATAAGCATGGAATATGTTTCT ATTTGCTTGTGTCATCTATGATTTCTTTCAGCAGGGTTTTGTAGGTTTTTTTTTTGTAGA GGTCTTTTTACCTCCTTGGTTAAGTATATTCCTAATAATTTAATTTTATTGTCTTGCAGC TATTGTAAAAGGGATTGAGTTCTTGATTTGATTCTCAGCTTGGTTGCTGTTGGTGTATAG CACGGCTACTGATTTGTGTACGTTAAATATTTATACTAAGACTTTGCTGAATTCATTTCC CAGTTCTGGAAGCCTTTTGGATGAGTCTTTGGGGTTTTCAAGGTATACAATCATGTCATC AGCAAACAGAGACAGTTTGACTTCCTCTTTACCCATTTGGATGCCCCTTATTTCTTTCTC TTGTCCAGTTGCTCTGGCTAGGACTTCCAGTACTATGTTGAATAGAAGTGGTGAAAGTGG GCATCCTTGTCTTATTCCAGTTCTCAGGGGGGATGTTTTCAACTTTTCCCCATTCAAGAT ACTGTTGGCTATAGGTTTGTCATAGATGGCTTTTATTACCTTAAGGTATGTCCCTTGTAT GCCAGTTTTGCTAAGGGTTTTAATCATAAGTGGATGCTGGATTTTGTCAAATGCTTTTTC TGAGTCTATTGAGATGATCATGTGATTTTTGTTTTTAATTCTGTTTATCTGATATACCAC ATTTATTGACCTGCAGATGTTAAACCATCCTTGCATCTCTGGAATGAGACCCACTTGATC ATGATGGATTATCTTTTCAATATGCTTTTGGATTTGGTTAGCTAGTATTTTGTTAAGGAT TTTTACATTTAGGTTCACCAGGGATATTGGTCTGTGGTTTTCTTATTTGGTTATGTCATT TCCTCGTTTTGGTATTTGGGTGATACTGACTTCATAGAATGATTTAAGGAGGATTCCCTC TTTTTTTTTTTTTTGGGAGTCTTCCTCTGTCGCCCAGCTGGAATGTAGTGGCATGATCTC GGCTCACTGCAACCTCTACCTCCTGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAGT AGCTGGGACTACAGGCATGTACCACCACGACCAGCTTAATTTTTGTATTTTTAGTAGAGA TGGGGTTTCACCATGTTGGCCAGGATGGTCTTGATCTCTTGACCTCATGATCCACCCTCC TCGGCAACCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCAGATTCCCTCT TTCTCTATCTTTTGGAATAGTGCCAATAGGATTGGTACCAGTTTTTCTTTGAAAGTCCAA TAGAATTCAGCAGTAAATCTGTCTGGTCCCAGACTTTTTTTGTTGGTAACTTTTTAATTA CTATTTTAATCTGCTGCTTGTTATTGGTCTGTCCAGAGTTTCTATTTCTTCCTGGTTTAA TCTAGGAGGGTTGTGTATTTCCAGGAATTTATCCATCTCCTCTAGGTTTTCTAGTTTATG CATGTAACTGTGTTCACAGTAGCCTTGAATGACCTTCTGTATTTCTGTGGTATTGGTTGT AATATCTTCCATTTCACTTCTAATTGAGCTTATTTGAATCTTCTCTCTTCTTTTCTTGGT TAATCTCGCTAATGGTCTATTAATTTTATTTATCTTTTCAAAGAACCAGCTTTTTGTTTC ATTCATCTTTTGGATTTTTTGTTTGTTTATTTGTTTCAATTTCATTTAGTTCTGCTCTGT TCTTGGTATTTATTTTCTTTTGCTGGGTTTCGGTTTGGTTTGTTCCTGTTTCTCCAGCTC CTTGAGGTGGGACCTTAGATTGTTTATTTGTGCTCTTTCAGCTTTTTGATGTAGGCATTT AATGCTATGAACTTTCCTCTTAGCACTGACCTTGCTATATCCCAGAGGTTTTGATAGGTT ATATCACTACTACTCATTTCAAAGAATCTTTTAGTTTCTATCTTGATTCCATTGTTGACC TAACAATCATTCAGGAGCGGGTTATTTAATTTCCATTTATTTCATGGTTTTGAGGGTTCC TTTGGAGTTGATTTCCAATTTTATTCCACTGTGGTCTGAGAGAGTACTTGCTATAATTTC AATTTTCTAAAACTTGTTGAGATTTGTTTTGTGGCCTATCATTTGGTCTATCTTGGACAA TGTTCCATGGCTGATAAATGGAATGTATATTCTCCAGTTGTTGGGCAGAATGTTTTGTAA ATATCTGTTAAGCCCATTTGTTCTAGGGTATAGTTTAATTCAATTGTTTTGTTGTTGACT TTCTGACTTGACCTGTCTAGTGCTGTCAGTGGAGCACTGAAGTCCCACACTATTATTGTG TTGCTGTCTGTCTCAGCAACACAATAATAGGTCTTGTAGTAATTGTTTTATAAATTCGGG ATCCCCACTGTTAGGTGCATATTTATTTAGGACTGTGATATTTTCCTGTTGGACTAGTTC TTTTATCATTATGTAATGTTCCTGTTTGTCTTTTTTAACTACTGTTGCTTTAAAATTTGT TTTGTTTGATATAAGAATAGCTACTCCTGGTGGATTTTGGTGTCCATTTGCATGGAATAT CTTTTTCCATTCTTTTACCTTAAATTTACATGAGTCTTTATGTGTCAGGTGAGTCTCTTG AAGACAGCAGATACTTGTTTGGTGAGTTCTTATCATTCTGCCATTCTGTATCTTTTAAAT GGAGCATTTAGGCCATTTACATTCAACGTTAGTGTTGAGATGTGAGGTACTATTCTATTC ATCATGCTATTTGTTGCCTGAAAACCTTGGTTTATTTTTCATTGCATAGTTGTTTTATAG GTCCTGTGATATTTATGCTTTAAGGAGATTCTATTTTGGTGTATTTCACACATTCATTTC AAGATTTAGAGCTCCTTTTAGAAGTTCTCATGGTGCTGGCTTGGTAGTGGCAAATTCTCT CAGCATTTGTTTGTCTGTAAAAGACTATCTTTCCTTCATTTATGAGGCTTAGTTTTGCTG AATACAAAATTCTTGGCTGATAGTTGTTTTGTTTAAGGAGGCTGAATATAGGACCCCAGT CCCTTCTAGCTTGTAGGGTTTCTGCTGAGAAATCTGCTGTTAATCAGATTCTTTCCTTTG TTGTGACTTTAGATAACCTGATGACTATGTGCCTAGGTGATGATCTTTTTGCAATGAATT TCCCAGGTGTTCTTTGAGCTTCTTGTACTTGGATGTCTGGGTCTCTAGGAAGGCCAGAGA AATTTTCCTCGATTATAGCTCCAAATATGTTTTTGGAAAAACTCTGACTTTTAGACTTAT CTTCTTCCTCAGGAACACCAATTATTCCTAGGCTTGGTCATTTGACATAATCCCAAACTT CTTGGAGTTTTTGTTCATTGTTTTTAAATTTTTTTTTTTTGTCTTTAATAGATCAGGTTA ATTGAAAAGCCTTGTCTTTGAGCTCTGAAGTTTCTTCCTCTACTTGTTCAATTCTATTGC TGAGACTTTTCAGGGCATTTTGCAATTCTCTAAGCATGTCCTTTATTTCCAGAAGTTGTG ATTGTTTTATATTTATCCTCTCTATCTCACTGGAGATGTTTCTATTAGTATCCTGTACTA TGTTTTTGATTTCTTTGAGTTGGACTTCATCCTTCTCTGGTGCCTCTTCAATTGGCTTAA TAGTCAACATTCTGAATTCTTTTTCTGGCAATTCAGAGATTTCGTCGTGATTTGGATCCA TTACTGGTAAACTAGTGTGATCTTTTGTGGGTGTTAAAGAATCTTGTTTTGTCATGTTAC TGGAATTGTTTTTGGTCCTTCTCACTTGGGTAGATGTCAAAGGGAAGATATAGGACTTAA GGGCTGCTGTTGAGATTCTTCTGTCTCATGGGATGCTCTGTTAATGTGGTGCTCTCCCCT TTCCCCTAGGGATGGGGCTTCCTGAGAGCTGAACTAACTGTAGTGATTTAGCCACCCAGT GGAGCTACCCAGCTCTGGGCTGGTACCAGGGAATATCTGCAAAGGTCCTGTGATGTGATC TATCTTCAGGTCTCTCAGCCATGGATACCAGCACCTACTTGGTGGAGGTAGCAGGGGAGT GAAGTGGACTCTGTGAGGGTCCTTGGTAGCATTTTTGTTAAGTGCACTGGTTTTGTGTTG GTTAGCCTCCAACCAGGAGGTGGCACTTTTAAGAGCACATTAGTTGCAGTAGTATAGGGA GGATCAGGCAGTGGGTGGGGCCATAGAGCTCCCAAGAGGCTATGTCCTTTGTCTTTGGCT ACCAGGGTGAGTAGAGACAGACCATCAGGTGTTAGGCATATCTGATTTCTGACTCTCCAT GGACAAGGCTTGCTGCCCAAGGAGTGTGGTTTCCAGGCCAATGGAGTTATGTTCCCAGGG GGATTATGGATGCCTCTACTGTGTCACACAGGTTGCCAGGGAAGAGGAGGAAGGCCAGCA GCCACAGGCCTCACCCAGATCCCATGCAGCCCTCCTCACCCTCCGCCAACAGCACTGAGT TTATTTCCAGGCAGCTGGTGGTCAGAGCTGAGAATTTGCCCCAGGCACAGTTCCTTGGCT CTCCCATGGAGCCTGCAGTGGCAATCCACCACCTTCAAAGGGTCTGTGGATTCTCTCAGC TTTCCTGGTATGTTCTTGTGGTAGTTCTTGGAGCACAAGTTCATGATGTGGGTTTCCACA TGCTTCTCTGTCTGTTCAAGTGGGAGCTGCAAGTTAGTCTTGCCTTCTATCCACCATTTT CCTACCTCTTTCACCATTTTAAATATATCCTCTACATACAGTATCAGCTTTTGCACATAT GCATGGCATAGAGGTTAAGAGAATGATCTCTGAAGTCTGACTACCTGCCAGATCCTAACT CCACTACTTAGTAGTTGTGTGAATGGGGCAAAGTTTTTAACCTCTGTCAGCCTCAGTTTC CTTATTTGTCAGGACTGTGTCTCATAGGATTGTTGTGAACATTAACTGATTTAAAGGAAT TAGAACAGTGTTTGACATAAGATAAATGCCTAATGGATCTTTATCATTAAGACTCTATGC ATTTCCTAGTTATTTTAATAACAGTCTTATTCACAATCAGGCACTATACCCTTCCTGTGG AAAAGGGAAAAATACAGAAAATGAGTAAAAATGACATGTATTTCCCTTATCCCACCACTA AGAGGCAATTTATGTTACCATTTTGATGTGTTTCATTCCAATCATTTTTTTTTTACTTAA TTAAACTTTTCCACTTATTATCAATGGATATTATTATCAATGTAACCTTGAGCAAATCAT TTACCTCCTCTAAGCCTGGCAAACTTTGTATGTAAAATAAAGGTAATTTAGTACCTACAT TATAGGGCTATTGTGTGGATTAATTGAGTTATACCATGTAAATTACTTAGCTGGGTACTT GGCCTATTTTTAGGTTAAACAACATGAAATTGCCAATATTCACCTTTTTTTTTTACTATG AAAAAGGCAATTTCATACAGTCCATCCTAATGAGAATATCTCAATATACTTATTAGCTTT TTTGATAAGGCTTTGCAGGGTGTGATGGTACACAGCAAATTGCCCTTGGGCTTCAGCCCA CAAGGAGACCACACTCCTACAGGCAAGGAAACATTTGTTTAAAAAGAAACAAGCAAACAC CTGCAAGGCAAAGCTGATCATGGCCTAACAAAGACAGGTTAAGTGTTGGAAGATTCCAAG CAAGGTAGACTACCTCCATCTGCAAGGATTCAGGGTGGCTCTATGATAAAGTTGACATCT GAGCCTGACTCAGAGCCTGAAGTCAAACTTTCCTGACATTTCCTACCAAAATGTCAGGAA AGGCTTTCTAGGTAGAGGGAACATTCAAAGCAAAGAAAGAGCAGTAGGAATGTACAGTGT ATAATTTCTTTGGTTAGAACATAGGGTACATGAGAGCTGGAGGTGGAAGGCAAAGCCTGT GTATTTTAACACTCAGCACAGTACTTGGGCCGTGGCTGGCACCTGGTATGTGCTTGAACC AGTGCATACTAAGGGATGTGAGCTCTGTTCAGTAAAAAAGAGAGTGGGACATTTTTGACC AAAGGAGTACAATTGTCAGTGCCATCCTTTGGAAAGTTGAGTTGGGGAATATATGTATCC TTGAAAACTTGAAGTGAAGCTCCTAGAGGCAGAGACACTTCTGTTTGTCCAGGGTCCTGC TAAGCTATCCAGCCTCATTTCCAACCTTTCCTTCCCTCCTTTTCCCCTACCTCCATCACA ACTAATGTCTAACTCTGCTTAATTTATTTTAGTTCCTTCAACTTGCTGATCAAACCCTCT TGTGTCTCAAACCTTCATACGTGTTGTTGTGTCTGCTTTGAATCTCCTTCTCTTCACCAC TTGGCCAACTCCTGCTCATCTTCCATCTCGGTGGATACATCATTTCTTGTAGAAGGCTTT CTCTGACTCACTCTAGCCGGCAAATCTGGATAGCTTCTCTTCTGGGGACTCCCATAGCAC CCTGTACTTCCCACATGTTATCTGTCTCTCTGTACTTGCCGCCTAACTACTGCAGACTGA AAGTTCTAAAAGGGTGAAGACTATATAACCTATTGGCTAAAAGTGGGGATTGAGAGATAT GTATAAACCTAGTTCTATATCCCGATTCTGCAATTCAGTACTAGAATGACTTTGGATGAG TTACTTGATGTAGCTAACATTCATGTCTTATCTGTACAATGGAAATAATAACAGAGACTA ACTTTAGGGTTGGTGTGAGGAATGAAATGTGGTAGCATAGGCAAAGTTTAGCAGAGTGCC TGTAATATAATTAAGACATCATAAGTACTTATTAAAATTTTGCTGCTAGTAGTCACAATT GGACCCCTTGGAGTGCTCCACAGCAGCACACTACTGGGAGCATACTAGGTGTGCCAAATA TTGTTGGATGATTGAAACAATGCCCGTGGAAATGATGAAGATGTAGATGTGAAAAATGTT TTAGAGGTAAGAGCCAATAGAACTTAGCAGTTTACCTAATTATAGGAGGAGACAAGGTAG TGGGCAGTCTTTAACTCAGGCCTGAGCCTAGAGAAAGGGAAGACCAGTGCTGCTTTTTTT TTTTTTTTTTTTTTTGGAGCAGAAGTGGTGGGTGAGACAACATCATCAATTCAGAACTCA TTTAGGGAGCATACTGAGTTATATGTTTAGTAGCAAGCTCAACCAACATTTGGTCCTGGA GCTGGGGAAAGAAATTATAGATGGGAGAAAGGCATGAATTTCATTTTAAGAAGGGGGACT TTTTTGAGCCAATGCTTCTCTAACTTTAGTGTGCTTTGGAATAACCTGAGGAGGGTTTTA AGGGGCATGCTTCTGGGTTTTATCTCTATAGATTCTGATCAATAAGGTAGGTCTGTGGTG GAATATGCATTTTGACAAATAGCTTAGATGATTTCACTGTGACTTTGAACAAACTATTTA TTATGAGTTTCAGTTTCTACCCTTATTAAATGAGAATGGTATCTACCTTTTGTAGGGTGA AAAGGAGGCGAGAACACGCAGGGGTGTGTGTGTGTCTGTGTGTGCGCATGTGTGTGAAGG TTATATAAGGAAAGGAAGTAAAGAGTTTCTGGAAGAAAACATGGTATCCCATGTGGTATG ACAAGTCAGTAAAGGAAGGAGCGAGTGAGAAATGAAAGAAGGTTAGTGAGTTTGACATGC AGAAGCCACAGATGAGAAAATTGTGTTCTTGGACAGAATACTAGGGCAGGAAGAGGTTAG GAAGAGGGCAATGGGTGTTCCTTACTAATAGAATATTTAATGACACAGAAAAACATTAAT GACATGTTTTTAAGTAAAATATAGTATAAATCAGAATGACACTATGTTTTGTTATAGCTA AGTAGTTATATTATGGGCAGTTTTTATTTTCTCCTTTTCATCAATGGTATTTATTAATTT TTCTACAGTTAAAGTATTGGTTTCATAACAAAAAATAAACAGTCTTGAATTTTCTGAGTG GAGCTGAAAGAAAAAAGGTATCTCTAGGGATTACAGGACGGAGAGAAAGGCCTTTTCTTT TAAGGTCAGAAAACATTTTTGCTTGCTCTTTAGAGAAGGTAGAGGTGTTGTCAGGTGAGG ATGAAATCCTGGAAGAACCAATCTGGAATTGTGTCAGATTGAAGGGTTATCCTTAGAATG GAGAAGGGAGACATTTTATGAAGAATTTCAGAGACAACTGATGAAAATATTAATGACAAT ACAAGAGCTAAAAGTACTGTCCTTTACATGGGAATTTTCAAAATGCTAGTTCAATTGTTT TAAGATATTTTAATTAGAGCACGAAGTCACAGATTTGATCCCCTAATGGACCAGTTAACT TCTTCTCATTCCTAAAGGCTAAATAACTTAAGCTAACATCAGACACCTGTTTTGTAGAAA GATGTCAAGGGTCACCAAAACAAAAACACCATGCAAGAGAGGATGAATGGATCATTGCCA ATTTATTGGTATCATGCAAGGAAAAGCACATATGTATTCATTACTAAGGTGCTCCAGTAT GACTTAGAACCTAACCTTACCTGAAGATCTGATTGAGGATGTAAAACCCTAAATCAAAGC TCACGTTGTAAAGTTTTCTTTCCTTGAAATGAACTGCCCGAAAATGTTTGCCCATAGAGA TCTAAGAAACACATTTTCAGGAAAATTGGTGCTTATCTGGACACTCGAGGGCATTGGTCA CTGATTTCTAAGGCTGATGATTTATGATATCGTCTTTCATGTAATGAGTTTCAGTTTTCC TGGATATTCAGACTGTTTCACCCTCTCTAAACCTTCCCCACTCAGGGAACTCATCAAGAG GATCATGGATCACAGTCATCTGAGAAGAAGCTATTTGAGTAGCTTCTTTTGTGGTCAGAC ATTTGTTGGTCCCTAGAGCGTTTACTAAATGGGACTCGATTCCATTTACCTGCCTGGAAT GCTGCAGTTTTAAGTACTCCCTACTGGATTCCTGTCTGTAATGTCTTCTGAAATGTTGCC TGGTAGTATAACAGAAGCTGCAGGGTTGCAGTGCATTCATTTAATTATGCAGGAATAATG AGAAATTAAATAGCATTCTGATTCACAACTGAGGCTGAATCTGTAGCTGTTAGAAATATG GATATTGGTGTCAGACAGAATCTGGTCTGAGACCCCCCTCTGCAAATCATTAGCTCTAAA TCTCTAAGGCTCAGTTTCTCAACTGTTGTATAAAAGTCACTTCCTTTATAAGGTTATAGT GAGTAGTGAATAAGATAATGCATGTTTATTAATTGTATAGTACCTAGCATATGTTAATAG TAAATGCTTACTAAATATTAGTGGTTACTACTTCTCCTGTTACTGTTACTTGTCCATATA CCCAGAGAGTATCTCCAGAAACATAAAACAAGTGTGTTCCAAGGAAAGATATTAATTTGC CACATAGCCAGAACATAAGATTTATATAGGAATGAAATTAGAAGAATTAGCAATTTTCCT TTCACAGTTAAGGACTTTGGATAAGAACATGATTTTGGATAGGTGCTCTCTGGGGGCAGT TTTGGGATTAGCAGACATCAAAATCCAAGACATTATATCCATCTCCTAGGTCAAGGCAGT TGAGAAGCACCTGTTGATGGGACAAAGGAAAATAAAGTGTGAATTCAAAAAAAAAAATCT TGCTTATCTTCAATGCTAGATTTTGTGTGAAAATATGTAAATAGGTCTGTGCAAGTTTTG TGTATAGTTCAGACAACATGGATTGGGGGTTCAGACATTGCTTTGGATTTAGACAGATCT GTGTTTGAGTGCCTGATGAATCACTTTACTATCTGTGAGCTCCTGAGCAAGATACATAAC CTCTATAAACCATATCCTCCTCCCTCTGTGGAAACTAATATAGATGCTGAACACCTGTTA GCAGAGAGCATGGCATGAGATAAATAATCAGTACATGTTAGTTATATTTTTCTATGTGCG AATGTGGCGTCAATATGTATTCAGGCAGACAACAACATTTTATCCCTAGGAAGTTCTCAT GTGTGTCCAGATAAAATCAAGAATTTGTTTTTCAAGCCTGTTACTGTATTGATATAGAAA TGAATAACCCAGAGATTCTTTTTTCATAGAACCCTTTCCGGGCAATTAACATATGAATTG CTCAGATAGCCACTGGGGACAATCACACAGCCTAAGGAAGTACAGGGGGAAGGGCTATGG AGGCACAGGTTCTATGTGCCCAGTACTGTTCCAAGCACCTGCCAAGTAATCTCTTTTGCA AACCTCACATTAATGCTATGAGATAGGCAAATCTCATCTGTATTTATAGACAAATAAAAT AAGACTCAAAAAGATTAAGTATCTTGCCCAAAGTTATATAGCTTGTGAGAGAAGGCAGGA CTTAAACCCTGGCCTGTTGTCTTTAAAGGCACTTTTAAGCTAGTGTCAATTGTGTAGCAA AAACAAATGTAATATTGTTATGACTATATTGTGGAACAACAACAGAACCCCCATGATGTC CCGGTGTACTCTTGTGAGTCTTAGTTTGACTGAATTGATCCCAGATGTTAAACGCTAAAT GCAATGCACTATTTTAGGTTTTTTTCTTCCTCCCTGCTATTCAGATGCAACCATTAACAC AGTCAGGAAGTAAAATGTTACATCTGAGATAAATGCCATGTTCATGTTCCTTTTTTCCCT CTCTCATTGTGTAAGATAAGAATTTTGTTATTATGCGACAATAGTTTTATTAGGAATAAA ACACATGTAGGTTCATATGCCTCCAGGGCAATCGCATGCAGACAAGGAGCTCAGCACCCA GCAGGCATGCATATGGGAGTTTCTTACCCAACTATGTTTCTACTAACCTTACTTTCCTTA GCACCTACAGTGGTTTCCCCAGGCCACATCAGCCCAGGGGTGAAATTCAGTGGTGGAATA CCATTAACAAACAATATCTCTTTGACTGTCTATACTTTCATTATTGTGTGACCCCATCCC TACAGAAGGATTCCCTCAGTTATTACACAGAGAGTTGCTCATGTACAGAGTCTCACCAGA TACCAAAGACTATCAGCTGGTTTCTTCCTCGCATGTTCTGACTTCCTGAAATGATGGTGC TGTGCAGGCTTGTGTGAAGTAACTGGCTCAGTCTCCAAAATATGCTGTTTTGGGGCCTCC AAAACAGCATTTGGAATCTTAAGGATACTGCTTGGTGCAGCAACTGAGCAGCACCAAGGG CTTGCTGTGTTCTCTGGAATTCCTGAATCCACATCTACTTCTGTATGCTTCAGTAATGGG CGAATACCCAGCTCTCCCATTTGAGTGCTTTACTCTATAAACCATAGTGGATCGGAGTAG GGGTGGAGAATCATACTCCCTCCTCCTGGGGTCTGAGTTTCAGCTCTTCTGTCTGGTGGC AGTGTGACTATGGGCAATTATTTAATCTCTGTTTGCCTACGTTTCCTCATCTGTAAAGTG GGGTTAACAATAAGAGTACTTACCTCACAGGGTTGTACCTAGTCCAGAGTGAGGGCTCAG CAAATGTTGGCCACTGTTAATATTGTATGAGTCCTCAAATCTAACTGGCTCTGGCACCCA GGATACAGTGCAGAGATTTTTATCTTTTCCTCTTTCACTTTATACTTGCAGCTCCTCTCC CTAGGACTCAACCTTGAGCTGGAGGATGCTGTGAGTAGTAAGCACTTGGGTTTATTCAGG AATGCCCTGCTTTCCAACTCTGTGGCACTAACCTTCATTACATTTGTGTGCCTTTATTAT TCCTTCCTTAGGTTTGACTAGCTGGCTCCTCGGTTGGTCCCTTGAGCAAATCAATTCTGT TGGTACTAGGTTCGCAGGCATCCAAATGGGCTAAGATATGTCTGATGTTTGAATCCTAGC TGAATTTCCTTTTGGCTCAAGCTGGAAACAAGGATTCATATTCTCAATCTGTCTCTCTCG CTCTCTCTCTCTCTCTCTCTCTCACACACACACATACACACACACACACACAGATAGACA GACACATGGAGTTATATTTTTTCAGCCCTGAAACCTTCCATTACCATTTGGTTATATACT TGACTTCTTAGATATACTTGAATTCTTGTTAAATCTCATTCAAAGATACTTTTTCACTGA AATTTCAACAGAACGTCATTGTGAAATGATGTTTTATATGAAACCTCCCAAGTAATCTTT CAGTGATACTAATTAGTTCTTCAGTTACCTGAAACCAGAATTAAAGAATTGTTCACTAAT GAAAACATTCACTTTAGCAGTTTGTTCAAGAATACCTATTTGTATGACTTCTAGATAATA AATTATCTATTCTTCTTTTGTTCTTATTCAAGTACTATGTAAGTATCAGGTAATCCACAT CTGCTATTCTTGCATCAACTTTAAAACATTTAATTCTTTTTTCCTCGTTGAGATTTGAAT CACAAGGATTCTTTTCTAAAGGCAAAGTTGAAACAATGCTTCCAAGACAAAAATAGCATT ATCCCTTATGCCAGTAATATTTGAACTTAGGTATTCATCTACTCTCACTTTCCTGCTCTT TCTTAGTATTAATACACTATTCAGTGTTTGCTTGTTACATGCCAGGACATTTTACATCCA TGAGGTCAGACTCAACTGTTATTTTGTGAACTATGAAGTGTATATATATAATAGTTTTTC ATTCAACACATCAGCAAAGATTCCAATTTAGGTTTTAGTAAACTACTTGCATGTTTACAG AAAAGTCAAATGCTCACTCCTGTTAAAGTATGGCAATCATTTCCATGTTAAAGTTTATTC CAGAGTCTTGAAGTCAGCACATTTCCAAGTAGCTGAAAAACAACTGCAATAATAATAATA ATTAATATTGACTGTATGACTACTACATGCCACCCTATGGGTGAGATAGTTTACAATAAC TTTACAATAAATTCATTGTGCAGGTCCTGTTATTATTCCAGTTGTATAAATAAGGAAAAT GAGGTTCAGGGAAGTTGAATATGCCACTGATATGGATTCAGATTCATACAATAATAGTGT TTCCTAATTCTGATGAGGCTGTAAGAAAGACCTGAGTCACCAAAACCATCCCCACCAGCC AATGGGGAGTCTCAGCTGGCATAACATATGAACCAGGTAAGTGAACATAAATGGCAAGAC AAGCCATGTGCTGTGGTCAGCCTTCCAGGGCTGGCAGCATTGCTCCCCGCAGTGCATTTC TATTGAACTAATCATGGTTAATGTCATCAGAATAACTTCTCAGTGAAGCAAGAATCTCCT CACCAGCAGGAAACTGATAAAGATGGCTTGAGGATGCATGAAACATAGCCTTGGACTGGC TTCATGCTAGATGCCTTTCAAAGATGTGTAGCTGCATGCGTAACCTAGCAAGTTGCTAGA CTGATTGGAACTGCTCATATTGAGCAAAGGGCTGGCTGCAAGTCTAGGAAAGTGGAAATG TCATAAATGAAGAAGGGCTCTTCGGATGGCAGCCCCACTTAATAACTGATTGCAGGGCAA TCAATCTTTGCTCAATATGTACATGTCCCTCAGTTGATCCAGCATTGGCCTTCTCAGCCT CATCTGTATACACTTGATGTCATTTTCTCATCAAGTATGCCGTCTCTAAAAATAAAAGAC AGCAAGCATTACTAAAGCTGGAATGATTGCTTCTAGGCCTTTTGGCTAAGATCAAGTGCA AAAGCTGGAATGAGAATATTCCTTTGCTGCCCTCTCAGGCTCTTAATCCTGTCTTTCCAG AGCAGCTTATTTATACTACAGAATTTGTGATGTGTTTAATATATTTCAAAGTTTTTTCAT TTGTTTTTAAATGAGAATTTATGGAAAGGGTTCTGCTCTGAAAAGAGAAGCAATTGGAAA AATGCTTAGAGATGGAGGTACCAGTGTGTTGGGCTGCTCTGTGGGGAGTTGGGAAGCTGA TTCCTGTAATATCTTATCTTCCCTTCTCTCACTTCTAAAGATTGCTATGCCATGACAGTT TGCAAAAACTTTTGGGCACTTTTTTTTTTATTTAAAAATATTATTTTTAGCGTCTCAAGT GATTCCTTCACTTAAGTCATAGTGCTTAGTATTTCTGCATTTACTGTGAATTCTGTTGGA AATAGCGATGATCCTCTGAGAGACAGCTGGAAGAAAATGCAGTGGTTCCTCTCTTGGAGG AAGGAAATGTATTTCCTGAGCAGAGTTGCTCTGCTTTGTAATCTCATGGGAATATGCTAA TGACCCTGAAAACTGAATTTATTTTTTTAGAAACACTGTTCTGTGGTTTCTGGGATTTTG GCTTATTTGTAAAGATGGCAAAGACTGGTTCTAGAATTCTTCACTGAGGCAAAATATGGA AGATAAATTGAGGAAACTAAGTATTAAATATATAAATGATAATATTGGGACCTACTCAAA AATGTGTAGTTTCTTATAATTTGCTGGATTATTGTGGCTGTTTGTTACACTAGTTTTATA ATCACTTATAATAATTATGAAAGCTAAAGAAATAGTGATATCACAAGAAATTTTTACTTC TGGACATCCCTCGGTGTAAGAGTGATGTAAGGTCCCCACCTGTATGCGGGTGGGGGAAAA GACAGCCCTTATGCCCTTTCCTGCAGGTTCCAGTCAGTCCATTGATGGGCAGTCTGTATC AGACAGATCTCTAGAAAGTCTGCAGTTTCTGCAGGATTTGTTCCAGATAAGAACAGATAA GAAGATAAGAGAGCTCTATGGGAATAAAGAGGCTAAGAGTGGGTACAGTGCAGCTGGAAG CTGGACCCAAAGAAGCATTTTTAGGACTCTGGAAAGACTGAGTCAATAGAATAGGATTTG AATACTGTTTCTTTACATAGCAGCCAAACAAATTATCTAAACCTTGTTTTCTTCACCTTG TTTTCCTTTTGATTCTTGACCTTAGGTATGGTTTTCTATATTTAAGATGGGAATATTAAT AACAAAATTTACCTTGTGATTTTCAAACATGCATTATTTAGGAATGTGCTTTTTAAGCTA TAACAGAAAAACAAGTTATTCTTAGGTCTGCCAAAACTTTGAACACATATTTAATGCTGA GAGCCTAGAAATGTAGAGTAGTTGACATTTGACCCACTAGTTGGCCTTGGTAGATAATAC AGCAATAAGATGCAGTACTAACGAATTTCAAAGATGAGTGAATTTTTTTCTTTGTACCAC GTGAAGTACTTCCTAGAATGAGTAGCTTCTAATGTGTTATCCATATATTGAATTACAATG AATAAAGGAAGTATTGTGATAGAATGGGAGAGAGCTTGGACTTTGGAATTAGGTAAAGAT GGGTTTGGAGCCAGTTTCTGATAATAACCAAATGTATGATGAAGTACTTGACTGAGAGTC TCTGTTTCCTTGCCTGTAGAACAAACATAAATATCCCTGCCTTGCAGATTTTACGCAGAG ATGATTCATGTAAACTACCTGTACAATAAAAGATCAATACAATGCCATGATGGCCATGAT GATCATCATAAAAATCAATTCTAATTAATAAGCTCAATTGCTGGCATAAACAAGCAGAGG TGCCCACCACTGCACCCACTCAGTACTGGATCGCTTCTCAGTACTGGATGTAGCCTCTGC ACTGTCTTGAGTTACAGAGGACAAGTGAGCAGGCTGTGGAGCTAAGTAGCCTGACTTCAA CTCCTGAATGCCATTTACTGCGGTAAATGGTGGTTAATTCAGATAAGAGATTTATGCTAA ATACAATTCCATGTGTCTTCTCAACAGATTGTATACTTTTTCTAGGACTATTTGTGGTAT TTTGGGGCTAATTCATCTCAGATGGCTAGTCATTTGCTCCTTATGATATGAGTAGGTTAG ATTATCATACATTGCCAAATTAATTACAATTCTGAGAACTTCACCACTTGTTAAATTACA TTGCCTCTCACAGAAGGGAAGATAACCAAACAGATGAACTCCTGGATGATAACCATCAAG TTCAGGCCAGTGAGGTGTGCAGATTGAAGGAGGGCCAGTTCCCAGTATCTGTAAGCTGGT CCTCGGTGGCCTCTGTCTACTTTAGCATCTTGGATACTGCCAGGCCATGGAAGGAAGGCA AATTGTTGCCAACGAGAATGAAATGAAATTAACATATGGCTACAATAGAAGAAATAGATT TAGTCCATGGATTGACCCCTCCATTTAGAAAGTCTCAAGTGAAATCAGTCTGGAAACTTA CCAGGCTTTTTCCATATATCTGTGAGTATTTTATACTTTGGATGGTCTTCCTATACACAG AAAGAATAATGAAGGCCTCTTGATTCAGAAACTCTGAATAGCAGCTTGGTACTATGTGGA TATTTAACAGATCAAATTCTAAGGTTAGCCTCATTTGGTCCTTATTGTCTTAAGTCAAGG TGAATAGAATGAAGGGACACAATGTGTAACCTTCTTTATTTTCTACTTACTAAAACATTT CAAGATCAGATCCTTTCTACTATAATAGTATCTTTTCAAATGAAGGCAAGTACAGATCCA GAATAATAACATGTAAAGGACACTTAATGCACAGTGGAGTTTTTATAGGTGAAATATTCC AACAAAGTATTGGTTATACCCCACCGCTAAAGAAACCACAAAATGACTGCTTAAACCAAT TCTTCTCTATATACCTTTCCCTTCTTCCATGGAAACCAGAAACTCTGGGTCTTGTGCCTT CCATGGTTTCTCCCTTTTAACAAATATGCCTTGTGTTCTTTCACTTACTAATTGGTGTCA CCATGTGCTTATATTGCTAACAATTTAAATAGAGCAGTTCCTTTGAAAATATAATCTCCT TTTAAATGCATCATCATTTTGAAGTGGTCTCATAAATTTTGTTGCTGGTTTGGGACCTTA AACGGTATATTTATTTATATTAAAGTCTGCCTGCTGTTCGTCTTGAGATATTATATTTGT ATAGTTAAGAGAAGTGATGAGCCAAATTTAATTTTCTTTCTACTCTGGAATGCCTTGCAT CTTGTAATCACCATTGATTGCCTACTTACTAGTCAGAATCAATAAAAGGAATAGAGGTAA AATTGTCCAATCTCATGTTTTGTAATATAATAGTCTAGTCAAAATGGAGGGTACTAATAG CATTCAGCTGCATAGACATTATCTGATAATGATAGTGTGTATAGCTCAGACTACAGAGAA ACAAATTAAAGCTGGAAGCTCAAATATTGGACTTTATTTTATTTAGGATAAGGTTTATGC ACAAATCTCATCAGAATATGCTTTTTCCATTTTATGGATAATAATGTAATTTTTATTAGC TTTTTATCATTTTAATTGCATTTCCTTTCAGAGACCACTAACATGTTCTACTTTTGTTTC AAGGTTGTCTCTAATATGACTGATACATTTGCCTAAAGTCCATCAATATGAGATTATGGA AACATTAAACCATATAGACCTGTCTGAGAATAACAGCTTTCAATTTCAGGTCTATATAAA TAAGCAAAATCTTGGAGATAGAAGATAAGAAATACTACTAAGCAGTCAGAGACTTGGTCT GCTATTTTTAAGCATTCACATTTCTCTACTTATTGTGCTTTGTAGATTTCAGAAAATACT TTTATTGAGCTTAAATATTTCTAACAGGATTGTTGTTTATATGAAGTCTCTTGAACTCTA GCATTCCACTGGGAGTAGACTTTAGATCACTCAATGATATTCAAACTTTTAGGTCTTTCA GTAAACAACCTTGATTTTAAAAAGAAATGCAATGTGTACAATTTCAAAGCCCATCCTTAA ATGAGCTTTACTGAGGAAATCAATCTTAGCAATTGATAAATTACGTCTTTTATTGGAAGA GAAATTGTGCTCATGGCATTTTGGAAAACATTCAGCATGGTGGTCAAGTTCTTTTAGTGA GTTCCCCGCCGATCATGGTCTTTCACTGTTCCCCACATCTAGAAGCCAGAACCCTTCCCC AGATAGCTTTCAAATACAATGATTAGAGAGTGTACATGGAATAGAAATCTTACTTGTAGA TTTTGATTAGGGATTAATTACTTAATTTTCTGTTGCCTGTTCAGGATGGTTAATGACCAT ATGGCTTTGACATTTTTTTGCTCCTTTTTATATTAAGTTTTTCTTACTGGAAACCATGTA ATTAGAACCACCTTTCCTATCTCATGTTCCTGTCTTCATTGGCATCTACTCTAAAGCCAT ACAGGATTTTTGTTTCAGAATAAGAGTTGCATTAGATCGAGGGGCGGATAATTAGCTGAA CTAATTTTGCCTGTATTGTTCTGTCACTTTATACCCCGGAGCCCTGGAGATAGGCTTTTT AGTTATCGATTTTTACCTTTATATGGGATAAAATTTTGTAATAGAGAGGGAATAACTTAT ACATCTAATAGCATAATGACGTAATGGGCTAGGGCTGTTAAGAGAGGGGGATTTGAGATG GAGTCTCACTCTGTTGCCCAGGCTGCAGAGCAGTGGCATGATCTTGGCTCACTGCAACGT CTGTCTCCTGGGTTCAAGCGATTTTCCTGCCTCAGTCTCCCGAGTAGCTGGGATTACAGA TACCTGACACCAGGCCCGGCTAATTTTTATATTTTTAGTAGACATGTGTTTCCCCCATAT TGGCCAAGCTGGTCTTTAACTCCTGACCTCAAGTAATCTGCCCACCTCAGCCTCCCAAAG TGCTGGGATTACAGGCATGAGCCACCAAACCCAGCCCCTTTTCAGTTTTTTTTTCGGAAA TGTATGTTCAGTGATAGTCATTTTTCATGCTTATTGAGTGCTTACTCTGTGGCAAGCACT GTTCTAAATACTACATATGTTTCCTCTTTTGATCCACGCAGCCATTTCATGAGGTAGCTA TTATTCCCCTCTATTGTATGGATAAGAAAACTGTTGCACAGAGAGGGTAAGTAACATGCC TAAGATGATACAGCCAAAAAATTACAGAAGCAATATTTGAATTTCTCTTCTTCCCACTCT TAACAACATATTCTAATCACATATAAGCCCAAAGTCAACTGGTCCCCATGGAGAAAGCAT TGATAGTCGGGAATCTTTTATTAGATAAAAGCCAGTGATTAAAATGAAGTGTGGGGATGT GCTGCTATTGAACCCACAGCTTCTAAATTTATCAACACTGGAACTGCTCATGCAGTATCA AGCCTCATGCATGGAACAAGGGGACAGGATACAGAAAGATGGGGCAAGACCTCCAGCAGA GTATCATGCATAAGCACAAATGAAAATGGCCCTTGGGAAATAATAGAAGCTAACTTTTAT TGGGTGCTTTCCATGTGCTAGACCCAATGTAATGCAATGTCTTATTTAATACAGGCTTCC TATAATTATTCCAACTTTATCAGTGCAGCAATTGGGGTTTTAAAAGGTTAGGTAATTTTC CCAGGGTTACATAGCTGATAAATGACAATAGGGGAGCTCAACTCCCTTTGTCTGATTTCA AAGGGCATGCTCTAGGACTTGAGATTTCAGTTCTGACACGGAAAGAGCTTAGAAGCCATC ACTATTGTTTTAAAACCAAGAAAAACATGGACATTGAAAGTCAGTGACTTCCATGGACCC ACTGGACTTTTTGGATCCATCAGAAACGTGGTTACTGGGCAAATCAACATCGCAAATTCC GGAGAGACAGGCACATTAAAAGAGAAATGACCTACATCTTCATACCTAGCAACCAAGCCG CTGGAGCCACATACTGGTAGGAACATGTCAATGATGATTTTGATGAATTGCTAAACACTG AGTATAGACTGTTATGGATGTGAAAAATGCCAGGGAACCTCAGCCTCTGGTCCCCACACT TTCATGGGCTTTACCTTCAGGAGCTCCATCAAGTTCTCATGGTGAAGCTTCCATCATTGC TGTGGTTGGAAGGAATTATTGCAGTATATACCCAGAGCCTTCTCCATAACAAAGGCTTTA ACTCCACAGTAATAGACTTTATCCTCAGTTAAGGAAAGTATACTCCTTCCACTTTTGATC CCTTTAGCCTGCCAATCTCATCTAATAGAGAAAGAAATAGGACATAGGGGTCAGATCTTC AAGGAAATATATTGGGAATGCTGCAGCCAGGGAAGGATATTGGGAGATGGTGGGAGGGAG ATTAGCTATGCCCCTGGAGTAACTTTGGGAAGACTACATCCCACTGTCCAGGGCTCACTA AGATACTGAAATTTAATCAGAAGATTATAGAATGCTCCCCTCTCTCACACTCTGCCCCCA CACCAACAGAGTCCCAGTGTAATAACAGTGGATTACAGCTGAAAAAGCTGTAAGACACAG AATCTCAAAGTCAAGAAGGAATACAACATCAAGGATGCCTACATGCATTTTACACATGTG TGCACACACACACAGACACACAACAAATCTAGTCATATCATGTTCAATCTGCAGAAAATA AAAAACAGAGAAAATCTTGAAATTAGCCTGAGGAAGGAAAACACCTTACTTTTAGAGGAA CAAGTGAAATAATTACAGTGGACTTCTGGTCAGAAATTATTCAAGCAGGAAGAGCAGGGA GTGAAATACTTAAAGTGTTGAATGCAAAGAATGCCAACATAGAATTCTACATCCATCAAA GTTATCCTTCAAAAGTGAAGATTTAAGTTTTTCAGGCAGAAGGAAGAGGTTATAAGTCAG AAAACAGGCAGGCAGACAGACCTAAGGCATATGTGTTATTAAAGGTATGGGCAGAGAGTC AGAAGATAGGAGCACTGAAGGAAGACAGAGGCAAAGTGAAGTATACAGATGATGATCCAG ATAGCCAGGGTTTGAGGAGCTCAGAGTGTGGTCAGAATAGAAAAGATTGCTTAAAGCCCC TGCATGCCATCTAGGCTGAAAAATGGTTTATAATGTCATATGATTTGGCTATGTCCCCAC CCAGATCTCATCTTCAATTCCCATGTGTTGTGGGAAGGACTCAGTGGGAGGTAATTGACT CATGTGGGCAGGTCTTTCCTGCACTCTTCTCATGATAGTGAATGAGTCTCATGAGATCTG ATGGTTTTAAAAATGGGAGTTTCCCTGCCCAATATTTTTTTTTGCCTGCTGCCATCCCCG TAAGATGTGACTTGCTCCTCCTTGCCTTCTGCCGTAATTGTGAGGCCTCCCCAGCCATGT GAAACTGTGAGTCCAATTAAACCTCTTTCTTTTGTAAATTGCCCAGTCTCAGGTATGTCT TTATCAGCAATGTGAAAATGGACTAATACAGTAAATTGGTACCAGAAGTGGGGTGTTGCT GAAAAGATACCCCAAATTGTGGAAGCAACTTTGGAACTAGGTAACAGGCAGAGATTGGAA CAGTTTGGAGGGCTCAGAAGAAGACAGGAAAATGTGGGAAGCTTGGAACTTCCTAGAGAC CTGTTGAATGTCTTTGACCAAAATGCTGATAGCGATATGGACAATAAGGTCCCAGCAGAG GTGGTCTTAGATGGAGATGAGGAACTTGTTGGGAACTGGAGCAAAGGTGACTCTTGTTAT GTTTTAGCAAAGAGACTGGTGGCATTTTGCCCCTGCCCTAGAGATTTGTGGAATTTTGAA CTTGAGAGTGATGATTTAGGGTATATAGTGGAAGAAATTTCTAAGCAGCAAAGCATTCAA GAGATGACCTGGGTGTTGTTAAAGGCATTCGTTTTTATAAAGAAAGCAGAGCATAAAAGT TTGGAAAATATGCAGCCTGACAATGCAATAGAAAAGAAAATCTCATTTTCTGAGAAGAAA TCCAAGCCAGCTGCAGAAATTCACATAAGTAATGAGGATCCAAATGTTAATCCCCAAGAC AATGAAGAAAATGTCTCCAGGGCACATCAGAGGTCTTCATGGCAGTCCTTCCCATCACAG GTCTGAAGGCCTGGGAGAAAAAAAGTGGTTTTGTGGGCTGGGCCCAGGGTCCCTGTGCTA TGTGCAGCCTAGGGACTTGGTGCCCTGTGTTCCAGCTACCCCAGCTGTGGCTGAAAGGGG CCACTGTAGAGCTCAAGCAGACCATGGCTTGAGAGGGTTCAAACCCCAAGTCTTGGCAGC TTCCAAGTGGTGTTGAGCCTGCAAATGCACAGAAGTCAAGAATTGAGGTTTGGAAATCTC TGCCTAGATTTCAGAAGATGTATGGAAACACCTGAATGCCCAGCCAAAAGTTTGCTGCAG GGATGGGACCCTCATGGAGAACCTCTGCTAGGTCAGTGTGGAAGGGAAATATGGGTTCGG ATCCCCCACAGAGAGTGCCTACTGGGGCACCACCTAGTGGAGCTGTGAGAAGAGGGCCAC CGTCCTCCAGATCCCAGAATGGTAGACCCACTGACAGCTTGCACCGTGAGTGTGGAAAAG CTGCAGACGCTCAACACCAGCCCTTGAAAGCAGCCAGGAGGGATACTATACCCTGCAAAG CCACAGGAGTGGAGCTGCCCAAGACCATGGGAACCCACCTCTTTCATCATCGTGACCTGG ATATGAGACATGAATCAAAGGAGAGCATTTTGGGGCTTTAAGATTTGACTGCCCCACTGG ATTTCAGACTTGCATGGGGTCTATAGCCCCTTTGTTTTGGCCAATTTCCCCTATGTGGAA TGGCTGTGTTTATCCAATGCTTATTACCCCCATTGTATCTAGGAAGTAACTAACTTGCTT TTGATTTTACAGACTCATACTTGCCTTGTCTTGGATGAGACTTTGGACTGTGGACTTTTG AGTTAATGCTGAAATGAGTTAAGACTTTTGGGGACTGTTGGGAAGGCATGATTGGTTTTG AAATGTGAGGACATAAGAATTGGGAGGAGCCAGGGGTAGAATGATATGGTTTGGCTGTGT CCCCACCCAAATCTCATTTTGATTTCCCACATGTTGTGGGAGAGACACAGTGGGAGGTAA ATGAATCATTGGGGCAAGTCTCTCCTGCGCTGTATCTGTGAGCGTGAATGAGTCTCATGA AATCTGATGGCTTTAAAAATGAGAGTTTTCCTGTACAAGCTTTTTTTGCCTGCTGCCATC CACGTAAGATGTGACTTGCTCCTACTTGCCTTTCACCCTGACTGTGAGGTCTCCCCAGCC ATGTGGAACTGTGAGTCCAATTAAACACTTTTTTTTTTTTGTAAATTGCCCACTCTCGGG TATGTCTTTATCAGCAGCATGAAAATGGACTAATACATAATGCTTTCCATATTCCTGGCA TTGTCTTGTATTAAGGTAAAAAAAAAAATGAATACGATGTGGCCCATACACCTAGGAAGC TATGCTCCAGAAAGAGGCGAAGACAAACTGTTATCACCCAGTTCATTGATTTGTTCAACA CAGGATTTTTTGAGTGCTGACTTTATACCAAACAAGGTAGTAACTGCCAAAATGAAGAAG TCTAGAAAGTGCTATGAAATCACAAGTCGGGGAGCAAATATAATGCCTAGGATTGTGAAG GAAAAGTATACATGGATAACAGGAGAGTTAGGCCTAGAAGGAGTAGAAAGTAACAGATAA GAAGCTGAGCAAGCAACATAGGCTGCCAGAATGTAAACAATTTGAATGGCAGACATGGAG CACTAGAAATATCTGATTTAGAAAATTTAATGAATATTTTATACTTTGTCTCAAATCAGT CTTCATGGATTATATAGCAAGACCCAGATCAAAGACAAACAGTAGATTGGAATGGAAATG AATGGGTGGGACAGGTTTGACATCTCATTTTGAGTTTAAATATCAGATCTGAAGTACTCC ACATTGTTCTACCATTTTTTGGAATTAACACCTGAGATTAAGCCTACTGGACATTCTTTA TCCAAGCAAGAGTAAGAAGGCTGTTTTCTGGAGGATTGCTGTCTCTTGGCCAGAGATTAA ATCCTATCATTCTGAAAACCACAGCAATGATAGATAAATAATTCGACCAAAATCCAAACA TTGAGAGCTCACAATTTGTTATTAAGTCTATCAGACCCCTGACTGGTATAGGCCACTGGA GCCATGATGTTTAGTTATACTAAAGAGAGAACAAGAAGCCATCACTGACTTCTGGTCAGG TTGGCTTAGAGTTGGGGTGTGGGGCAGAATAGATTAGGACAATAGCTTGGGACAGGTGGT TAAATAAAAAAAAAATGTCCTTGATAGTGGAGGTGGATCTCAATATGAAATGAATCATGA AATAAATTGAAGATAATACTAGGATCTCTATAACTGTTCTGTTCAACAACAAGGTCACTA GCCATTTAAATATAAATTTGAGGTAATTAAAATTACATAAACACACAGATCATCAGTTAC ACTAGTCACACTTCAAGGGTTCAGTAATCACATATACCTGTTGGCTACCATGTTGGACAT CACAGACATAGAACATTTCTATCAATGCAGAAGGTTCCATTACACAGTAATGTTTTGATG TATGTGAGGTATGATGATACAATAGAGAAATGCAATTAATGTCTTTCAGAAACAACTACA AAATTGCTTTTTTTTAAAAAAATGTTTATATTTTGGAAGTGAATATAGTAAAGGTCTTGC AGCATAATGCCGTACTTTGCCAACAAACAGTTTTAGGGATGTTTATCCCTTTTGAGTGGA ATATCCTTATTTTTTTTTTTTTTTTTTTACACATTACGATATTTAGTTTTAGTGAAGTCA GGTCACTTCACACTAGCAGTAAATGGTGACGGTCAGTAGTTGAAGTCACGCTGCTTAACT CCAAAGCCAGTGTACCTGACCTTTGCACTCCAGAAGAGCCCAGAAGCCACCTTTGGGACT GAGGGGCCACCTGTGGTGTAGTAGAGGGCAGACATCTCTGCCTGTTTATGCCAGAACTGA ACTTAGTAGTGAAGGTGTCCATTCTGCTTGTGCAGTGCCCTGCTGCAGCAGTCATTTGAT GTTGTAATATCAGTTTTGCCAAAAAATGTGCACATTCCTCTGCAAATCCTTCTTGTTCTC TGAAAAGCATTGCATGTATTAAGTGCTCTTCATTAATACCTGGCTATCTGTTGGGTGTTC ATGAGTCCAGTTTGATTTTCATTGTTCAGTTAGTGAAAAAAGGTGAACAAACTATATGCA ATATGAACACACTAGGTTTTTCTGTAGTGAAGATTGATGTAAATTTAACCAATTAAAATA TTTTAACAAATAATTTTGCTGCCATATGCTGGAAAAATTGCTGAATTTCTCAGTTAATCA GAAATTATGTGAATTTCCTTCATTTAACCTAGGCTCTGTACTCTTAGTTTCTTAGTTTCT TTTTTTGGGAGATGACAGATCTAAAACGAATTTCTTTAAAATCACTTCGGATTTTTTTTT GAAGTACTAATTACATGATTCCCTTACTTTTTGGAAGTAACTATTGAGATTTCTTCATTT AAAAATATTTTTAATAGTAATAAAGCAGATCCTTACTAAATATTTTGGGACTGAGGAATT TCAGATAAAATGCAGTTTTCAGGCTGTGACATGGACCTTCTACTCTTTTGGAAAGCTTTG GATCATTTGTGATTGACAGTTCAAAAATACAGTGATATGTTTTGTCTAGCCCATGTCATG CTGGAGAATACTAAATCAATAGTAATGTTATCAAAACCAGAAATCAAATGCAAAATAGTT CCCTTAGTTTCCTGCATAATGACATTTGCTCTTTTGATAAATTACTAATGGGTTCTTGGA CAGGAGACCTCCTGGAACAGCCAAGCCTGGGTATAAATGGAAAGGAGGAAGCGGTAATAT TTACTATACAGAAAAAAATTGCCTTCAGTTAATGTTCTGTATAATGTCCAAATATAACTG AATTCCGCATTGTGATAGGATATTAGTAAAGAGGCCAAGAACAAGCTAACCATAAACCAC AGTGTTTTAACCCTACTAAAAGTAGTTTAGAGCGTCCTGCACTAAATCATGCATCCTACA ACCAGAACAACTCAAACAGGACAAAGCATCAGTGACCAAAGCAACAGAATGCCAATAGTT GTGCCACAGTTCTACCTGAAATACCCTGTTCCCTCAAGAAAATGCAGTCATTGGCACAAG GGCATCACTACTATACCATGTTTTAAAAAATTTGATTGCTTAATTCAATTTGGGGGATAA CTTGATGCCAGGAACATATTTTAGGGCAAAAAAAGTCGGGAGGGAGTCATATAATTGTCT TTAAAATCTTGAACCATCAGTTTTACTTTAACTTCTCGAGAAAAAAAATCTTGAACTGAC TTAAAAGAGTTGTGACCTCCTGCATCACCGTGCTCACAGACGTTTTAGTTAAAGTTTTGA TTATGAAATGTATCATACATATATTAGAGTATGTTTGATCTTTAGGCCGGGCATGGTGGC TCATACCTGTAATCCCAGCACTTTGGAAGGCCAAGTCAGGCAGATCGCTCAATGAGCCCA GGAGTTCGACACCACCTGGACGTCATAGCAAAACCCTGTCTTTACAAAAATACAAGCATT ATCTGAGCGTGGTGTTGCGTGCCTGTAGTCCCAGCTACTTGGAGGAGGGGGGGTGAGGGG ATGGGGTCAGAGGAGTGGTTGGGGAGGCTTGAGGTGAGAGAATCCTTTGAGCCCAGGAGG CAAAGTTTGCCGTGAGGCAAGATTACACTACTACACTCCAGCTTGGGTGACAGAGTGAAA AAAAAGAATATGTTTGATCTCGCTCTCTCTCTCTTTATCTCTCTCTCTCACTCTCTCTTT CTATATATGCATATATTACCTAAAAATTTTTATGAAGTATATCCAAACACCGTCTAACTC AAAGGCTTTAGGAATCTGTGGTAAGAGAAAGTCTTCCAACCACATAGTTGTATTAAATAG TATAACAATTGCAGATTAGCCTCTGAGCTTTACTGAACACCAGATAATACCATGTAAGAT GTGTTAGGTAAAACAGCAAACCAGTCTGTTTCCTACACTTGTGGTCTACAAAATGAACAT ACCTAAAGCTTTGGATTCACTGTCATCCTAACCTTGTGCTGTACTTATAAGGTAGTTGCT GTATTTTTATATAGAAAATGAATAGGAAGACTTGCTTTGCTGCAGTAAACAAAAGATCTC TTCCCTCTCTCCACTCGACCACCTCCTCTCCCTAATGTTGTGGCTGGAGCTCACTGAGCT GCCGAAGTGGGAACATTTGTGCTTTGAAATACCTTTGTTTTGTTGGATTTATAATTTAAA GGGGAAAAATTTTTATACTGAAGAGTTGAATGCAACCAGAGAACAAAATAATAAAAAGCC TTATTTGAGAAGAAATAATTCTTTGGAGTAAGAGGTTAGCACATGTCAATATGTCATATA CAGGGAAAGTGAGCTTTTGATTACTTAGAGGTAAGGTTGCCAGAGGGTTTTTGATTTAAA TTTCTAAGGCTTGATCAGAGCATCAAGGGGTTTGTTGAAAATCCTCGTAACTTGTGAACT TGACTTTTATTCCTTTGAAAAATTATACAAAATATTTTTTGCCCACATTTATATTCCATG TGGCATGTTTCTCCTTGTAGCTTTGCAGCTATTCCTGTGCAGGCTTTATACTTGTTATAA CATCAGTGGTTGAATTGAATTTGAACATTGCTAGAAAAAAAGCAGAAAGTTTTGAAAGAG GAAAAGTGACCCAAAAGTTGGCTCTAAAAATGTTTCAAGCTTGCAGAATTCCAAGGAATA ACCTAAATGAACACGAATAGGGACTATTTAAATAAGTCATGGCACAACCTTAAAATGGAA TCCTATTTGCCGGCTTAAAAGATCAGATCCAAGCTATATTGAATGAAAAAGAAAAGTCCC ACCACTGTTAAATGCCTTGGTTTGTTCATTCAATATTTTGATGTACCTACACATAGAATA TATTTCAATGACAGAATTGTATAAGTTGGTTGTGCTGGGGTTTTTTTTGTTTTTGTGTTT CGTTTTTTGAGATGGGCTTTCACTGTATTGCCCTGGCTAGAGCGCACCAGCTGTTCACAG GCACGGTCGTAGTGTGCACTGCAGCCTTGAAGCTGTCCTGCCTCAGCCTTCCAGTAGCTG GGACTACAGGTGTGTGCCACCACAGCTGGCTTCTTATGCTGCTCTAGAGAGAGGGAAAGG AGCTATGTCTCAACAGACTGAGAGTTTTCGTTTTTTTTTTCAATATATGACTCTGCACTC GAATCATTTTAATGTAAGGATAGATATACCGATAGAAGAAAACTATTCAGTTCCTTATGC CCTCACTCTTTAAATATATTATTTTTCAAATTTTGTTAAAACTAGGCATTTTGTCCAGTG AAGTAAAGTGGCTACAGAAAATGTTAGGAGATTTTGTTTTATTTTGACATGAAAAATGAA ATTACAAACAAACTTGGAGGCAAATTAACCACTTAGCAATAGAGCATCTTTCAATCCATG GCAATAATTGCTGGAAGCTAAAAACATGCTAGTATAATAAATACATTTGAAAAATACACC TATCATTGCCGCTAATGTGTAGGTTACTAACTTTATATATAATGTTGCCTGTTGTTTAGT TTTATATATTTGCTTTATATACATAGAAACCAATAAACAAGAGTATGAGTGTTACCTACA TTTGCTTATCCTGTGGAGACAAAGTACTAATAAAATAGATACAACTTAAAAGTTTGAATG ATTTATTTTTCTCTTATGCTGCCTGTAACTTCTAAAACTCATGATTCTGAAAAAGTAAAA AGTGTTGACAATTTTGTTTCCCCTCCAAATCCCCATCATTTTAACTTGTTCTGAAATGTG CCACGTGAGGTATCCTGTATTATGTGCCCGCATCTGCTGCTCCATACAAACCGATGCTGC TGTCTTAGAAATAATAGGCCCCCTTTTATTCCCTAATAGACACTGCCATTATGTGAGATC ATGTTCAAGCTTTAAATTTTTCCACTCTGTATTTCTGTTTTCAGTTTATCTTATGGAATA AATGGTCCATTATTTCAGTAATTTTGTATATTGTTATATTTTTGAGTTTCCTTTCTCTGT GTCTCCCTCTTCCTTCCTCCTTCTCCTGCCAGCTCAAGGTGTTCTCTCCCTTCTTCTCTG TCTGTCTGTCTGTCTGCCAATCTAGCTCTCTCTCTTACACATGCCTTACACAGATCTTCT GAATGAGGTGAAGAGTGTGGCGCGAACAGCAGGACCTTGACTGTGGCACGGTCTGGACTG TGCATCTTGCACTGGAGAATTTAGCTGTCACTTTGGAGCCTGATAGAACTAGTGTGCAAT TCACATGCCCCAAGTCCTGAAAGGGAAACTGCATCTGGTGTCAGCGCAGTTCACTGATAA GATTTTATCTTTTCTCCTGCTGATACTGATAGAGCCATAGCCAGGTGAGCAGTAAATAAA GAAGATTTATTGTGGGCTGGATTTGTTAGCTAACAGAACTTTCTCGGAACTGTATCAAAA AAAGACCCATAAGTGTTCATCTTTCACATCTATAGAGCTCAATAATGAATGATGTGGTGG GGGAGGGACAGCGGCAGGAATTTATCCAGGCAAATTCCTTTTAAACAATAAACACTTCAT ACACTATCAGGCTAATCTGAATAGATGACTAAAAATCCAGTGGTTGATAAATTATCAGCA TGGCACCTGCATCTTATGCTTGAAAAACCTTGAGCAAACCCAGGGCTATACTTGTGGATT AATTGAGCATGCATAATTTACCACTGCAGTTTACGTAAGTGTAAGTATTTTTCTCATTCT GGTAAATAGGCATTTCCAGCTTCAGGAGAAAAATCAGAATGTTGCTGTACAAAGAAATGA GCCATCAGCCTATTTGGCTATTATAAGAAAAAAGAATCTCTGCTCTTGCCACCACTGCTT AGTTTTTAAATTGAAATGATTTTTCAAGTTTAATTTGCTTTTCTCCATTTATGTATATTT CTTTTTATTCATATTTATTGTCTTGCTTTTACTATTGTTTGTAATCAATACTGTTTTCTT AGTCTAATTTGATGCTACTTATTTGAATGATTTACAGAACGTTAATCTAGGAAAATACTT TCATTGCAGTTGTTTTATGTAGCCAAGGGTGAAAAGCAAATGCGTAGGGATTAAGAGTCA CAGAAACACATCAAGGTTTGAATGGCTTGCTGCGTATTATCACCCATGCGCTTTTTAATT AGGTGTTAATACTAAGTCACTATTTTCTCATCTATTAAATGGAAGTAATACCTATCCCAA AAATTGTTCTATTACATGTTATAATGAATAAACAGCCTCATTTAAAGCCAGAAACATACT AGGTGGTCAATAAATGATATGTATCCTTGTAATTCTCTTATTAAAACAAAATTTATTTCA TATATATCAGCTGTAAATTTTACATCCCTAGATTAGTAGTTTAAAAACATTTGTTGCTAT AGGAGATTTTATTTAATTATTATTTTTGTTTTGTTTTGTTTTGGAGACAGAGTCTTGCTC TGTTGCCCAGGCTGGAGTACAGTGGTGTGATCTCCGCTCACTGCAAGCTCCGCCTCCTGG GTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCTGCCACC ACGCCTGGCTAATTATTTTTGTATTTTTAATAGAGACGGGGTTTCACCGTGTTAGCCAGA ATAGTCTCGATCTCCTGACCTTATGATGTGCCCACCTCGGCCTCCAAAAGTGCTGGGATT ACAGGCTTGAGTTTATTTAATTATTAGTAGTAGGCTATACAATATAAAGTCAATATGAGA GTTTTATTCTCCTTGTTTAAGCAAAAAAAAAAAAAAAATGTCCTTGTGGGAAAGGAAAGC TTAAATGCAACTGTTTTTAAATGATACTATTATAAATATATTAATCCCTGTTTTACAATG GGGAAATACCTTTAAACCTCAATTGATGTAGTAGTCATAATCGTGAGTGGCTGGGTTTCC ATTTGATTTTTCTCATCTACTCCTATTTCCTGTAATATAATATATACATTATAATTTTAA AAATGTGTTTTACCTATGCTTAATTTTTTATTGCGGTAGCTACTAATGCTGAAATCTTAA ATTTTGCAATCTCAGAGCCCCTGTATAGTAAGTTATAAAAAATGTAAATATAATAGGAAA ACTGACTACTTAAAGGAGCTTTTCAGTGAATCACACATAAAATCCAAGATCCTGTTTATA ACAGAGGTTAAATTTATTTATATAGTAAATCTAATTTTTCATGATATACAACACCCATAT GTAAATTGTAATAGCCATCGTACGCTTCCTTTCTTGGTGAGAACTACAGCTATCAGCCAG GCATCGGGTTATTCCTATAAAGACATGTCACATTATCTGCCACTTCTCTGTGGCTTTATT GATGTGGCTGTCACCCTAGAAACCCAGCGGATTCGGAGATGAGGCTGTCTTCCTACTTGA TTTTTCACTAAAGTACATTTGAGGAGACCACTGTGAGGCTCTGGTGGAAGAAGCCGAAAG GGTAATTCTCCATAAGAATAGTTGTAACCTTCTGAGACTTTGTGTCTGCACTCATGCAAT TGGTCATTTCCTGAATACTAAGTGGGACTTGTCGCACCATTAATCATGCCACAACAGCAC CCTCAATCTTGCTTAGAAATAATCATTACTTAATTAGCTGGTCTTTTCTTTGTGTTTCTA TCTCTTTCAGTCGTAAGTTTAAAATGAGGCTACAGAGTGATGAAAAGGAGAGAAACAAGC TAAGAAGATCATGTAATGGCTAGCACAGAGCTTGGAGTTAGATAGGCCAAGTTTCTCTAC TACTGATGAGCTGTATCATGCAAAGTCATACAAGTTACTTAAAATACTTAAGACTCTGAT TCTTCTTCTGTAAAGTGAGTATAATAACGTCTTTCAGTGTGTGTTAGTGAATTCTTGACA GACCTATGCTCGAAAACATGGACCTTCTCTTCAATTTTTGCCTTAATACTGTGAGTTTGG GTCCCAATCTTAGAACTTGACCTTTTCCCTCCCCTCCAGATAACATGATCAGCTTTTCTT TGTCGGGTTCCTGAATGTCAAACTTGTAATGCCAACCATTTGCCACATAAAGGAGAAGAT CTCATTTACTCCTAACAAATGAGTTATCTTATAAAAAACAAAAACAAAAAACCAATATCA ATGTCAAGTGAAGCAAATCTCAGCTGTGGGCTCCATCAGCTATCCAGACCTTGAGAAGCT TTGTGGTTCTCTGCTCAGTTAATATGTGTCTGACACCCACCTTTTCAAGTGAAGCCAGTG CAGTGAAGTCAGTCTGGTGCTGCACAGATGAGGTGAAAAGTGGATGGAGAGGCTCAGACT CACCAACTACAGTTGTTCCTTCATTTAGATAGTTGTAGAGTTCCCATAGAACTAGGAGTG GTCATTCAAAATGATCCCTTGCCACGGTAGTAGACTTTTTTCTTTTTTTCTTTTATTTTT TAGCAATCCTACTGCCAACATGCCATTCTATTTAAATGGAAAATGCCACTGTGTATACTA TTATTGTAATAAGGTACCTTGTCTCCAAGTCAGAAGTTAAGAAAGAGAAATGAAAGTTTT CAGGCCTCTTGGCAGCTGGGGCTCAGTCCTGTGACCTTGCCTTTGTTAACCAGATCATTC TGTTTGGGGTCTTGACTCCTGAATGAGAATGGTGAGGATTCATTCATGATCACTTCGATG ATGGCAGTGGCAGCATCATGTCACAATGCTATTGGGTTCACCTATGTAATACGATGTCTT CTCCAATTTCTAGAGGGAGTAGCAGGTGGTGAAGCCAGTTTTTGGTTTAGGAAAGTCTGG GATTTGTAGCTGCCTTTACAAATTTGGTGCTCAACAGACATGAGAGGTAACAAGGAGTTA ATCTTACTAAGGAACTAAGATTACCTAGCGTACTTTCACTACCCACTTGTCCTCAGGTCT TCTGTGATTTAAGACAAGCATTTTTCATTGCTTTTGGCCACCAAGTAGAGTTCACTGAAT CTATAATGACGATCACAATATAAGCGATTTTATTAACCTGTCGGTTACTATACAACTTTC TTATTCTGGTCACATCCCAAATCCAGGAGGGTGGTGAAAATGCAAGACTGTTCTTTATTC CCAAAGTACTGAATTTCACATCATTCTTTCATGAATGGGCACAGGTATACTTGTATGTAT ATCTGGCTTATAAATCCTTAAGAATGTTGGTGGTTTACTTCATCAGAGGTTTATTATTAT TGATTGAAATGTAAAAGTTAGGCCGGGGGTGGTGGCTCATGCCTATAATCCCAGAACTTT TGGAGGCCAAGACAGGCGGATCATCTGAGGTCAGGAGTTCAAGACCAGCCCAGCCAACAT GGTGAAACTCTGTCTCTACTAAAAGTACAAAAAAAAAAAAAAAATTAGCTGGGCATGGTG CAGGCGCCTGTAATCTCAGCTTCTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGG AGGTGGGGGTTGCAGTAAGCCGAGATCACACCACTGCACTCTAACCTGGGTGACAAGAGT GAGACTCTATCTCAATAATAATAATAATAATAATAATTTAAAAGTTAGTTTGGGTAAGGC CGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTCAGATGGGCGGATCA CCTGAGGTCATGAGTTCGAGACCAGCCTCAACATGGAGAAACCCCATCTCTACTAAAAAT GCAAAATTAGCTGGGCGTAGTGGCGCATGCCTGTAATCCCAGCTACTCTGGAGGCTGAGG CAGGAGAATTGCTTGAACCTGGGGTGCGGAGGTTGCTGTGAGCCGAGATGGCGCCATTGC ACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTCAAAAAAAAAAAAAAAAAAAGTTAG TTTGGGTAACTATATGTGTATTTGGACATTATGTCTAAGACACTATTATTTGCATTGTTT CCTAGAAGTTCCCCAAATGTGTTATTGTGATGAGACTACCCTAAAAATGGGTTCTGTGTT CATATGAGTTTTCAGAGAACTACATAAAATCTCTTTCTCTTAATAATCCACACTGTATAT TAGCATGTTAAGGACTTCACAATTCCTGAGAAAATGAGCTTACTTCACATCGTTTGACTC AGAGTTTTACAAATTTGCATGACTACAAAGACCCTTCCTGTAAAATAAAAACTATGGGAC TAACACTTTATGAGATATATTTTGGGAAATGTTACCATAATATGCATTTTTCTATTGTAT TTTTCTGCATCACATGTTTTCACCAACAGATGCACTGGGCTTACATGGGAGAAGAGCAGG TACTAACAGAGATATTCATTTGTAAGTCAATTCATTCCAGTGGTCCTTCCCCATGGTGAC AGTCTCCCATGCAGTGTAGGGGCAGGGAGAAGTGCTTTTCTTGTTATATAAAAGGATCAG AAACTTATTTATTTACCTACATTTACCTACAGTCTTTGATGAAGCCTTCCTTGGCACAAA TTTATACCTTTAGACATAGGTCCAGATTGTTACTGTCTTCATAGATTTAATTCACTGATT ATTTTAACCAAAGAGGTCTCCAAAGTGATAAGATAATGAGATGGCTTCACAAAGAATGTA GAAAACTGAAACCTCTTCTGGTAAAAATACAAAGAACTGTATGAAAATGATACACACCAA ATTCAGGATGGTGGTTACTGCTGCCAGGATGTGGGAGGTGGTCAGGAAGTGATACACAAA GGAAGGCATGGCAGGTGTGCTCCTGGGAAACACTATGAAACCCTGAGGGTTGAGCCCAGG GCAGCCTTCAGGAATGCTCTCAAGAAAGACAGCTGTGAAAACATGTGGTGTTTGGTTTTC TGTTCCTGTGTTAGTGTGCTGACCATGGCACATGTATACCTATGTAACAAACCTGCACGT TCTGCACATGTATCCCAGAACTGAAAGTATAATAATTAAAAAATAAAAAAAATAAAAAAA ATAAAAGAAAGACAACTGTGAAAGAAAAAGGGAAGAAGAGAGAGGGAGAAGCTGAGCTGT AATACCTTTGCAAAACTGCCTTCAACCTAACTCTCGGTCCTTCAGAGATGTGTCCAGAAT CCAGGCAAGAGGGTCGGCCCTGCGTCAACCAGTCATTGGAAGTGAGCTGCTCCTGGAGAG GAAGAGAGATAGGGTGACCTTGGTCAAGGCAGCTTCAGCTGAAAGCAGCCAACCCGCCAG GCAACTGGTGGAGTGGGTGTCTTGGTTCTGAAGTGGGAATCTGGTAGCATCACTCTATGC CCTTCAGAGGATTTACCACCACTGGCAAATTTGTATTTGTTTAAATACAACATCTATATT TTATTAATAAAATTTATTTTCATGCATGGTTATTCTTACCTTATTCTTTATATCTTGTTA TTGTCTTCAATCATGCAAAATAAATTTTAAGAACAAAATGTTGAAAGAATACATTTATCA TGAAGAAATTTCATGCAGTAATGCTTCAAATCATTCCAAATCACTGGGAAAAGAATACGT TCTGCATGACTGACTCTTCTAGTTGAAAGATTTACCTAAATGCCAAAACTTTTAAACACT ATTTTTAAAGGAAATCTTACTAAAATCTTGCTCATATATCCATATCTTAATGAAAAGGCT GAAATGTGCATAATAGAATCTTTCCTTGATGAGTAAATGTTTTTATTAGTTTGGGTCCTC AAATATACTTTGTAGAAACTCGTCTTATCTCCCCCTCACATACAATTAATCTTTGTTTCT CTACTTGTATTCCAGCCAAACCATTCCCCTTTTTGGCTTTTAAACTTTTTTTTAAATTGG AATCACCATTCTCAAATTCCCTTAGGTTTGTAATCCAGAATCAGCTTTACCTCTCAGCCA CTCCTTCACTTTTGCATCTAGTTAACAAATTGGTCAACAAATCCCACAAGTTCTGCATCT TCACTACTTCTAGCATCTGCTCTCTCTTTCTATTCCCTGGCCATAAAACCTCTAACTGGA CTAGTACATTGGCATCTAAATTAATGTCTCCAGTTGAAACTATCAGACCAGTCTCCTACA ACTCAACTCTGATCATGTCACTTCACTACTTAGAATTCTCAGTGGCCAGAAGCTAGACAG TAAGGGCCCTTCCTGTCCACTGTTGTCTTACTTTGTCTCACTGTTGTCTTACTGTTGCCA CTGACCTCTCCAGTTTCTCCTCCCACTATTTGTCCCTAAGCACATTAGTTTCATCCATAA GTGCATAGTTTATGCTTTTTCAGTCTTTGCTGTTCCTATAATCTGTGGGCTCCTAAAGGC AGAGGAAAGCCTACATACCAAAATACTGAGAACGGAAGGGTATTTAGTTTAAGAGAGTAG GCTCTGGAACCAGCCTCCATGGTTTACTTCTATCCACTTACTAATTGTATGACTTTGAGT ATGTTACTCAATTTCTTTCTGCCTAAGTTCCTCATTTGTAAAATGAGGACAGTAGCATCT GCATCAGACGTTGTGAACTAAATGGTTCATAGATGGAATTGCTTAGAAGACTGCCTGGCT TATAATAAGCATTCTATACATTTTGTCTATTATTATTGCTTTTGTTCAGGCCAAATTAAA GTCTTCACTGGCACCTACTTTTATATAGGATCTTTTACTGTAGCCCCATGATGCATTGTC CTTTTAAAGCCATTTGCTGATTTGCTACTTGCTAATTGTATGTCTGGTCCCAGATTTTTT AATTTGGTGATTCCTTCCTTTCCTAATTCAGGAAATGTATTTTATCGAAAGTCACGGAAA CCAGTGCATGCAAGCTTAATGTTTACTGAATGGCTCCAACAGGTAATCATGCCAATATCT AAGAACAGGAAATTGCAGACAGCTAGGCCACATGGGATTAGGCTGAAACTTCTGTCTGTT CTAGGCCATTTCACACTGTTTTAGTCTGCTTCTGGGTTCTTTCCCTAGTTCTCTTAGCAG ACTGACTTTCTCTGCTCAGTTTTGCTGTTTCCCCCTATTCTTCTTGCACATGAGTGGATT GAGTTTGCTAAGACACTGATTACTGCTTGGATATCACTTGGCTTTGCATCTGGGCTCCCT ACAACTAACAAACACAGTCTTTTGGTATCTGAATTCCAAATTCTTAGGAAGTAGTATTTT ACTGGCTCAGGTGGAATATGGTTTGGTTCCCTAGATTAAGTGCCCCCTTCTATTTCAGTT GCTGTAGTCAAAGCTATAGCTTTATCTGATTCAAAGATAATAACTTAGAATATCCCTCCT ATAGCGGCAGTGGGTGGGGAATATTACCATTACCAAAGATGGGCATAGGCACAGTGCAGA TGCCACAAAATAGGCATGGATCCTGTCACCGTCTTTACTGGAGTAAGATATATCTTAGTG TATTCTTGCAGAATGCCTGCTTTCTTTACTCTCTTTTGCCACTCCAGAAGCACTAAAGAA TACCAGGGAAAACCTATTGGTACCAAGTATTTTGAAATCCACTCTTAATTTCATGGATGT TTTCCAGAACAGACCTACAAGTCTTAAGGTGGTTTCACTCAGCTTTCATGGGTTAAAACA GTCTTGAGAAAGCTCCTGGTACTCAGTAGAGTCTGACTTAAATTGAGGCTTAATGCCACT GTACATTACATTCCTGAGCCACATGTTTGTTATAAATGCAGTCTGGTGACTTTTTACTCT TGAGGGCAGCCACACTCCAATAAAGGTTTGGTCTTCATGACATAAGGTGAAGTTCAATGA TAAGAGTTAGCTGATAACATTTGAAATTATTGAATTTGGAATCCAAGTAAAGAAACAGCT AATAAGGAATATATCTTTATCCTTTTATTCTAAATTCTCAGAATTAGCTTCCATGTCACC CATTTTCCCCAGAAAATCAGCCAACTCTTGTAACCAATTTGTGTGTCACAGGTGTTAGAG AAGGGTACTCTTTTGGCTCTATTTCTCATTTCATTTCATTTTCATTTGTTGGGGCATGTA TAATTAAGTTTACCTGCTCTTCCCCAGAAGGCAATTATTGGTTTAGATTGCCTTATAATT GTCTCAGGTCTTTAATGGCTTCGCTGATATTTAGCAGTGTTGCTCCTGTTTCCTCTTTTA TTTTAAACCATTTGTCCTTTTTGTTTTACCCTGACATTGATCTGTGTTGTTCCTCTCTGC AAACAAAAGAACCAACATCCCACATTGCATAAACATTTGTGTCACACTTTCCTCTCGAAA TTAGTATTCTTTTAAACTGGTTAACACATTTGTACTGTCTCTGACACCTTTAACTATGAC AACTATGAAACAAAATAGTGAACAGTGAACAAACACATCACTGAAAACCGATTAGATTAA TTACTATTCGGGACAGTGCTTAGATTAATTATTTTGTTTGTGTAGTATGTTCGTTAAGTG GTTGCCTGATTGCTGCTTAGAAGATTGATTGCTTCTTACATTTACCTTGTGGATTCTGTG GGGAAAATATCTTTTAGGATTCATCACTTCTCAAAGCCCAGGGGGCTTTGTTGACATGAG AATGCTCCAGTAAAGCTGTAAAATGGAGAACCAACTGAGGAAAATGTGTTCTTTAAATAA ACACCTACAGTGGTGGCTAGAGTAGCCATCAGATCTGTTTAACATCAGGAGAAACAACTG ATGATAAAATTGAGTTAATACGAACTATACAATCTGAAAACCCAGCACACCAGCTGGATT GTAAAATTGAGGTGAATAAGCACTTACCAAGATTTTCTCTGTATCCAGTAAGCTAAAATA ACAAAGTCTTGGTGACTTTATGCTCATTTTACCTCTTGACTGTCATGTACCTCACTTCCC AGTAGCAGCCGCATGAGGACTGCTGCTGCTACTGCTGTTTGAGTCTGCCCTGGCAATGGG GCTCAAGAGCTCCCCGGGCTCCTTCTGAAGAATCCACACCACTGCCCTTTGAGGCGCTTG CCTCGCTGTAGGAAACTTCATGGGGTTATGTGATGCATAAGAGCATGCATTATCTACTGT GTTCAAGGGGTGACTGCCTGCACTAGGAAAGGATTTATGATAATAGGATTTTGTGCAATG GGGAATCGTAACAAATTTAAATAGAAGAGTACTTTTGAAAGAAAAAAAATGAGTTGAGGA TTAAAAATAGAACAGACTTTTGTTTAGTGAAAGACTGAGCTAATCTCTCCATTTGGGGAC ACAAAAATACATTGCTTGCCCATGATTGTGTATTATACCTATCTGTGACTTTGAATGCTT ATGGCGGTATTAGACACACAGCTTTAGTATTCAAAGAGGCTTCATACATCCCTGCCAAAA ATACTGTACCTTTGTCCAGAAGAGAAAGACTAAAGAATCTTTCTATGCTTCTAGTCTTTT GACCTTAATATTTGCATCTATTAATTATATTCATAAACAACTACAACACAATTACACAAA ATACTTAGATGTAGGGCACTGAAAATACCTAGGACTTTTAATACTATAGATTAAAACTAA GGAAGCATTATAACTAATATGCATCCCAGCAAATGAGAAGGAAATAACCAAAATAGTAAA ATAATTAAAATAAAAGTTGCCTCATGTTTTAATCAGTCTTCCCTCTGTAGCTTGAGATTT CAGAAGGTAAGCTATTTACAAACATAAAATGTTTTTAGCATTTAAAATCATTTTGAACTT AAGATTATTAAACATCGTAACCATCATGTCATTATGGCAAAGATAGTTTTCCTCCATAAA GACACAGTCATTGCCCAAAGGAGAAGCAGCCAAGAGCATAGGTATTAGGACAGTGATAAA TGAGAGGATGAGAGATGGAGTGGTTGTTTGTGATTTGGTTGGCTTTCTACAATGGTGCAA AGACTGAAATAAAAGGAAATGCATTAGCCCAGATGAAAATATATTTAAGGCCTTTTTGAT TAAGTTCTTCTTTTCCTGTGTGACTTGAAAGCTGAAACTCGATGAGAATTAATTTTTTAA ACATCTTTCTTTCTCATTAACTGCCCTTTTGTCTCTTTGAAGATACCTGTCTATGTTCCA GTCGAATACGAAATTCTAGTAATTCAAGTTTTTCAACTTACCACCCACATTCCTGGATTC TGACAGACAGTGGGGCTGAGACTATTGTGGGGATAAAGTTGCCTATATAACAAGTTTTCT CTGGTTTGAAAACTTAAGTTCAGCACATTTAGAAATAGCCTGGAATCTTGAAAAATGAGC CCTGTTTTTCATAGCATCCCTGATACCTTCCTTTCTTAGCCTATTCACACATAATTGTAT CTTTTACAACTAAAACCTATTCTATTAAAATGAATTGCTTATAGTTATTATTATACTTAA AACATAACTGTTTTGAGAAAGTTGAAAATATGTGTTTGGAACCTCACTGGGCTGTTCATA AGCTATTGTCTTAATTGTAAAAGCAACAAATTCAGTGCATCTGTAAGAATGTGATTTTAA GTTAATGAAACTAGTTTTCATGTGTTGTTTATTAAAGTTATTACATTATGGTCACATCTC AAACATTCTCTGTAATTATTTGATGGCTAAATGTGGCTGTCCTTTTAAGAGGAAAATGAC ATTATTGATCCATTGTTACTCCCCACCCACAATTTACTTTAATTGTCTTTTCCTCTTATG GGCCATGAGCTTCCCACTGGCCTCTCAATTTCCTCATGTAACCAAAGATATCTCTCAGAA GCTGGTAACCAGGGTGGTGAGTACTTGGTGTTTTCTGGAGCTATGAACTGCTAACTGGAC TCATTCATTCAGTCAGTCCATCAATGAGTAAATGTATTTATGCACTATTGAACACTTACA CAGATTCTACACCACATAATTTTATTTTCTGTATGAATAGATGGCATAACTCCTGTTTTC AGAGAGCTCAAAATTTTGTGAGAGGACCTGCAAAGGAGCAAGCAATTAACATAAAGAGTA TTCGAAGTTAGCGTAACAGAGCCCAGAGAGGTAACAGAAGGTGTCCCAAGGGAAGACAGA ATAAGAGCTCTCAGAAAGGAAGAGCTAAGGGGAGGATGTTCAGGCAGATAATGCCGCATT TGCAGGCAGTTGCAGAGAGAACCTTGCTCCAGTAGTTCCATGAGCCTGGACGGGAGGAGA GGAGAGAGCGGGAGAGGAAGACAGGGCAAGGAAGCCGTTGGGGAAGGCTTTGGAAGCCAT TCATTTGGCATTTACCCTGCAGAAACTAGAGAGCAAATGAAGGATTTAATCAAGAGAATG ACTTCTGTCCAATTAGTATCAAATTCTAACTGAATTAATCAGCCATACTTTATGCCCTTC CTATACCTGTCAAAATGTCCAAATTGTTATTTTTTTTTATTGTCCAAACTGAGTTGGCTT CCATTTCTGACAGATTTGACTTTGAAATGTTTTTGCTTATCTGACAATATGGAGATTTTT CTTTCTGGTCTGAATCTCTGACTGCTATTTTCCTTCCTCAACTACCTGCTGGAAATCTTT TATCATGCTAAATTAGAAAGGTAAATATGCTCCAAAAAATAATGGTAAACAATATTAAAA AAGAGATTATGTGCTATTTATATGATATTAACTACCTGCCTTTATCGTCATTTGGACTGA ATGAACCAGTTTAGAAACCAGTTTAAATCATAATTCATAACATTCAAAATAGAAAAAAAT CTTAGGAGGTCCTCGTGGAAACATCACTGAAATATATTTTTGTTAAAAGTATCCCAAGAC TGTAGAACAGCTAGATCTAGAGAAATATTTGAGAAAAGTAGGCCTTTTGATATGTGTCCT TCCAAATATTTATTTTGTATTTTAAGTATAGACTGGAAAATAAAAAGAATGCCTTTCATC TCTTTAATATTTTGCCTCAACTTCGCAGTCAGCTCTTTGGAACTAGAGGATTTACTTCTT TTTTCTTTAAGATAATGAAAAGACCAAAACCTATCAATATGGTCATTTTGTATATCTTAA TGAATAAACTGAAATGCTACACAGCGGCTCCAGTCACCTGATTTGGAATTGATTGTGAAT ATATCCAAAAATACGCAGCCAATTTGATCCCTGCATGTAGATGGGGGTCTATGGATGGGC ACTGTGTGGGGGGATTAGAACCCTCTTTGCATGGACTCCAGCTGAGAGAACCCTTCCACA TGTTAGCCAGAGACCCAGAGTAGGGGTAAGCAAATGTCCTGCAGAGGCATGGCAGAGAGC AAAATCACAGATGCAGCTTGCTAGAATTTCCCACAATCAAAATATCTTATTCTTCCAATG ACCTCAGCAATGAAAAAGTATCCTACATTTCCACATTAATAATCCAGTTTTCCTTTTCAT GTTTCTCCTTTGTTTCAGGAGCCTCAGGCCTAGGGTAACCCAGAAAGCCTTCTTTCCTCC AAGGTTATTTTATTATTTAGGACATCATCGGTGATAATAGGAGCTCCTTTCCCATTTTAA AATTTTGGACATGTAGGATTAAAACATTATATGAAAGACACTCTAGGGTTAATCACTAAA CCTACAAATGGCATTGGCAGTCTTGCCCTGTGTAGATAGGATCATCTATGTTTGGGTTTA TGGGATGAATATCATTAAACTGAATGCTCTTACTCGGATTATTTTTTTTTATTTAATGTT TTGCCCAAGGAAAGTCTTATTAAGTGTTGTAATGGCTCTAAGAGTTGTTGGTTTTTTTTT TTCATTTTATTAGTGGTTGAGGAAAAAAAAAAACCCATGATATTAGTAAAACTAATTGTT ACTACATTAAAATAATGCAGGTTTATCTCTGAATTAAAGCGTGTTACTTTATCTACTCAG ACAAGTGACCCCAAAAAACCCACCTCTATAATAGACTCCTTAAATTGCATTTTATTAAAA AAAATAAAAGAAGTTGGAGTATAAACTTAGATCCTTTTTAGTGGCATGCATAAGCATAGT TTATAATAACAGCAAACACTCATGGCAATTTGAACATGCCAGCATTCTTCCATGTATTAA TTTCCTCACAAGATACCTGTTTTAAGGTGGCTTCTATTATATCCTGATTTTCCAAATGAG AAAACTGAGGCATGGGAATTAAATAACTCACTTGAGTTCATAAACAAGGAAGTGGCAGAG CAGGATTTGAACTCAGGGTCCATCTCCACAGGGTACAATTGGCCACTTCACTGAATGCCT TTGACAAGGGAGAGAGTTCAGATTCCACGCAGTCAGCCCACTTTGGCAGGCGCAATCTTG AGGAACAGACTTTGGTCTGACAGTGTAGCCATCTTCATACAAAGAGAATAAAGTCTTTTT GTTGTTGTTGCTGTTGTTGTTATTATTTGTTTTAATCCTTGGAGAAAGGAAAAAAAAGTA AGATTAGAGAGAATGCATGTGTTACCTGAAAAATCCAAAGGGAAAATGGAAAATAAAGTA AGGCAATAATTTAAAGGAGTCCTAAAAATTAATCAGCTCTCTAATGGGGATGACCAAAAT TTGATTGATAATAGAGGCAGGAAAGTAAATTATTAGAAAATGCTGGCTTAAGAAATACAC TGTAAAAATGGTTGGGTTTAAAAATCATAAAACCATTATGATTGTAAGTACTTTATTATT CCAATTTTCTTTTCTATTTTTGTGCTATGTTTTTTTCCAGTATATTTTTATTCAATCAAA GCTCCAAAGCAGTTTGTAATGTAAAACTTCAAACTGTTTCCATCTGCATTACTGGCTCTT TCACACTAAAGTGCCCACTAGATCAAGGTAGCAAGTGTGTTCATTGGAAAAAGCTCGGTG CTATAAATAACAGGAATAAATTGACAAGGTTTCCTGAAAGGATCACCAGTGTTAGGAAGC ATGTGTAAGGCATGAAATGTAACACAGCTTAAATTTACTAGCCCATATAATCATCAAAAT TAGACTTAGGAAATATCTTTAAAATCATTTAGTTTAACTCTGAACTTATTATTTTGGATA ATTTTCATTGATATAAATCCAGAACCTATTAGAACTCATTTTTTAGGTTGTTTCCCTCAA GCTCTTCTCTTTAATTTTCCTTCCTAAAATATTATTCTGCTGGGAATGAATAATTTACAT TTGCTACTTCTGTTTTACCCTCATTATATGTTCCTCCCCCGCAAGATAAAATCTCCATCT TACTATTTGCTTTGTTCAAATACCAGTCAACTATTTCTCTCTAGTATGTGAGATGTGTGT GACGCAGATGACATATATCTTTCGCAGACTGATTTCTTTTGATTAGGTCTCTACTTTTCT TCTTTAAATAATTATTAAAAATCTTTATAGTTTTCTGTATATCTTGGGTCATAAATAGAT TTCAGCATTCTGTTATTTTAATTATAATCCTACTGATTCAGAGTCCAGAATAAGTCAGAA ACTTGCTAAAAATACTGAGCTAGGTGAGAGGGACACCATAGAGCCGAGATAGTAAAAATG GTTCATTCTCTTCATTTGAATGCAAATTATAGGTTATCTAAAATATGACTCTGGAATGCA CAAGAAGACACACACTGAAAATTAAAATTTTGGCCATGTCTCTTCATGATAGTAAACAGT GATTGAAAAGTGAAAATACTCATTTGATCCTCTCACGATACTAGTGTTCTGTGATAACAT CATATAAAGATGAATGAGCTTTTTGATCATCCAGCTTTCCAGATATCCTACTTGAACTGA CCTTGAGAAGAGTGATTTTTGCCAATACAAACTCTAAAGAGGCTTTGGCGAATGGAGAAA AGATGATCCTCTTCTCGCTGGCTACTTTCTGGGGCTGCTTTGGGACTTCTTTTCACACTC ACCACAGAAACAAAATGTAGGGACAATGGGATCCCCATTTCACTCTGATGTTCTACAGCA GGCAGAGGGTCTACCCTGCCACCAACAATAGCTGTAGTCATCACAACAGCCTTCATAGAA TGATATTCAGTTGTAGCATCAGCAATAAGACAAAAGAAAGTCCTGGAGTCACGTGCCCGT AGAAGCACCTGTCTCTGGCTTTTGGTCAGGGTCTTCCACAGCAGTCACTACCATCATTAC AAACCATGTGTTTCAAGAACACATTACTTTTGAGAATGCCAGGGCTGAGTTACTCCTGTT TGACATTCTCCCATCTAGCTTCTCTAGGCTCCAGAATAAGAGCATCCCCACCATTATTAC CAAATAATACTATTGTCAAGATGATGATGTTTAGAGATCCCAAGAAATCAGTCAGGTGAG TACTCCCCTTCTACACCACACACGTACCGCTCTGGTTTCTTCTGTTGGCATTTTCTGCTG CTTCTGTTGCCTGACAAACCTGATAAATGAAAGCCACTGATTCAAAGCCAATATTTTACA CAGAGAAAGGAGATTCCAGCTGGGACTACTCACCAAGGTTAGTTCATAGGCAAGAGAAAA AAGCAAGGAAAAGGATCTAGAGATCTTGGTGAACTAAAGCTGCAGCCCAGGTAAGTACAT CTGAAGAGTTGTACAGTTATGATGGATCAGAGCCCAGAGAAGTAGGAGTGCTGTTGATAT TACTCGTTCTTTAATTCATTCATTTTTAAAAATTATTTGTTCTTTAATTCATTGATCCAG CAAATGTTTACCAGGTCCTGGGTCCTGTGCCAGGTACTATACTAAGTACTGGAGATATGA AAATGAACAAGGTAGACATAATCCCTGCCTTCATGTAATGGATAGTCTAGTAGGGAATAA AGATGTTACACAAACATAAAAATGATTATTTAGTCACAACTATGATAAATGCTTTGTAAG CATCTAAGATTTTCTTAAAATACCAGACAACTTCCAGTAGCCAATTTGATAACAATAAGG GAATTTGTTAACATCAGGTGGAAAATGCTGGCAGTTAAAACTTTTTGTCTGCATGTTTCA CAGGATTTAAAAAAAAAAAGCTCTTCAGAAGATTTTAAACATTATAATTAATATTTTACT TTCAAGCCTGTTGTTGATTTTAGAAGATAAATTTGCTATTTAAAAAGATAACTAGGGCCA GGAGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACG AGGCCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATA CAAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAG GCGGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCTGAGATCGCACCACTG CACTCCAGCCTGGGCGACAGAGTGAGACTCCGTCTCAAAAAACAAAACAAAACAAAAAAA ACGATAACAACTATATTATAAGACATCATTTGTGAATTCCACATTCTCATATGTAAGGTA AACACAAAGTTTGTATGAGGTTCTCTGTCCGGGCAATGTTAACTATTGAAAAATTACATT CTAGGAGTTTACTCTGATTGAGGAAAATAAGATACACCTTAAAATAACCACAAAACAAGA ATATGAGCTAAGGCCCTTGGCAGTTAATGTACCTAAGTGCTGTTTACATATTTTGAAGCT AAACGTTACAAAGACTTTTTCTGATTTATATATTTACATTAAAAGTCTTTTACATTAAAA GTCTTATAAAGGTATTTTTCAAAGCCGTTACACATGTAGTAACACAATTAGTAAATCACA TGAAATCTGAATGACTTTAGAAAGACAGGGACACATGAGTGGAGACTGGGAGGACGACTA GGTTCACTACTTAGGGAGGCCAGAATGGAGTCTTTTGTGGGTAATGAGGGCAGTTCAGGG AGAAGAGGGCAGTAGAAAAGGTATTTTGTCACAAAAGATTAAAATGTGTCAGGGAGACAA GCATAGAGATTTATTTTATTGTTATAAAACAGAATATAAAAGTAGGTTGGGGTCTAACTA TTGTGGACTTCGAGTGATCAACGAAGGAGTTTATATTTTTTCTGATATTTTATGCCATTG AAGGTTTTAGGGCAAGGGATTGCCATGATCAAAGTAGAAGAATCAGTCTGGCTGCAGCCC ACATAATCATGGTGACATAATAAATTGTAATGACTCAAAGCAGTAGCTGGAAATTGAGAA AGAAATACATGAATTAGAAGGTGTTGAAAATCGCTTATGTTGACTTGAGACAATGGTATT CATCTTTTCTGTGAGTGTATTTGTCTTCTGTTTAGAAAAAGACAAAGCAAATGAAAAACA ATCTCTTCATTCACCTCCAGAAAGGGGTTGGGAAAGACAAATAAAGGGTTATTCATAATC TGTTGGTTACCCTCTGTTGGTAGTGGACAGAGATGAAACACTTTTTCGCTGGTGCACAAC TTTATTCTTAGCCGTGAACATCTGTAATTAGATGAACCACCATAGTGATGACTGAATTGA GAAATCAGCCCATTAGAGGATCTGGTGGTAAAGGAATGGAAATCATTATCTAGCACAAAT AATGCAAAGTTGGTCACTTACTCATGTGTGAGTTACTGTGCAAACAATTCTGATAAAAGA GGGGGGAATGCTATGGAATCAATATTGTCTTTATTGTGAAGAGGAATGAGAATGAACAAA ACCCTGAAGCTTTGAAATGTGGTAAATCTCAATACATTTACTCTGAGAATGTGACTGCAT CCCCACAGTTCTTCAGAGAAAGGATGTGTGGGTGTGAGAGTGAGTGGGTGTGTGGGAAAA GCTAATAACAGTTCTAGGTTAGCTTGCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT TCCTTCCTTCCTTCCTTCTTTCCTTCCTTCCTTTTTTTCTTTTTTTTTCCTTTACAAAGC CTTTACAATAGCAGTTTTACACCTTTGAGGCCTTTGCTAATTTTTGAGACATTTTATACT CTTTCTATTTAGGCATTAATCAGGAAATTGGTCTTTTCAAAGTGTGAATCATGAATAGTG AATATGAAACATTTTAAGAATGTAGTAGGAAAGATATTAGCACTTTGGGGAGGTTGCTTA GTGGAGTGAGGGAGCTAATGAATACTCTGAGTTATCTAGCTCTTTTCATCTATGCTAATT AGCCTTAACAAGGCAAGTTAAAATAATTTCTTTCCTAGGCTTGTACAGTGTAACTTCCCA CTTAGCATTTCTTGTCTCCTTACAAGCCTTATAACCTGAGGCAATCCCAGATATTCCCTT TGGGAAAGAAGTATTTGAGAGTTATGCTCACGGCACTTGCCTTTATTAATTTTATGAAAA AAATCCATTTTAACATTCATTTTCATATTTGAGTACCCAAGAATTTGAGGTTTGTATGTA ACCATTGTTGGGATTTTGTTAAAAGAAATGTTATAGTACAATCCATCATGACCCAAACAC ATCTTGATGAAATGTTCTGAAGTTTCCTATCTTTAAAAAAAATGTATTATGCTATTTCTC TTATGGTTCTTATCATAGTTTGTTGAAACATTCCAAGGAATTATAGTTCTAAGCTACCTT GTATTTGACAGATGTCAGTAGATGACAGGAGATTAATCTATAGTCCTCTCTCTCTCTTGT TATTTGATTAAACAGATCCATGCCACCATCTTTCCTTCTTGCCTGTAGAATACACACACA CACGCCCACAAACACACACACGCCCTTCTATTTTTCAGAATTCTTAGCCACACCCCCTCC CCTCACCACCACCGTTTTTCCACCCTGGTGCACATTTTTGTAGCCATTGCTCTTTAAGGT GACAGTGAGAGAGACTTCTTATCGATCATCTGACCTCCCACACAATTTGTTGGAGGTTGA CACACTCCCTGCCATTTTTGCTTTGTGGAGGCTGAAAGGCCCATTCATTACAGGGATGGC TTTATTAAAGAAGCAACCCCCAAATTCAAGTGGATTAAGCCATCTGGCTACAGAGTGAAA TCCTTCACAATCTTATGACAATCTATGTCCCCCATCCTTCCCTATGAAGTTAAAAGACTA TATATAGATTTTCCTTTCATTTTTTATAAATGCTCCTTGGATTTTTCTATCATACTGCCC TCTATTCTCTGAGGATAATTCTTAGCCATAGCTCCTTGTGCTTATTTCTTTATAAATTGG CAGTTTTTAAAATGAAAATCATTTTGCATCTATTTAGATGATCTCAACATTTTCTCTGTT TACATTAGTTTAGGGCACCTTTGAGTCATTTCCTTTTCATTTCTTTTCCATTTAGCCTGG ATGTTTGGCCCCATCTGTGGTTAGTGAGAACTGAGGCAGAAGCTGAGTCCACCCTTCAGT CACTCTGTACAGCTGTCCTTGGAAATTCCAGCCTTGAGGAAACATACATTCACACATAGC TTGTTTCCCCCGAAATAAAGGTTTTGATCAAATATGCAGGAAGGATGTTTTCTGTGACTT GGGTACAGTGGGAAGTTTTGCATATTGGCCTCTCTCACCTGCTGTTGAGCACCTTGGCTG TGTCTTTGTTCACCTCCCCCCGTCAGTGTTTTGCACAGCAGACACTAACAAGTATTTATT GAATGAATGAATGTGCAGATGAATGAAAGTAGCATGAAGGACTAATGCTGGTGTGGTGAT TGTGTCTTGTTTTCTCATTGTTCCAATATTCTATCTCAGTTTCCTCTCTCAGGAGAATGC CTCTTTGAAGTCCCTGAAGAATTACAGAATAGTAGATGCTGATAAAAATTTATACCAAAT CAGTAGGAGGATAAGGAAAGGAATGTAGAAGTATCTACAACTATACTTTGGTAAACTGTT ACAAATTCACCCCTCCAGGCTCTATAAATTACTTTGCCAGAAAAAAAAAAAGGATTTTCT TTCATGACAATTCAAATACAGCACTTCTCCTTCCCTGATTTTAAGAGTTTGACAATGAAT TAAAATGAGAGTCTGGAGGTAAGAGAACTTGCTGAAAGGGAGTCAACTAATAGTCAACTA ACTATGATTAACAGAATATAAGCACTGAAAATTCTCCATTGTGAGTTAAGATTTGCAGGC CTGCAAGCCTAGTGACATAAATGTCATATGCAGATTCTAAAAAGCAATGAGTTCTATCTG TTAGGTGATTTAATTATGTTGACCCTTAGTTATTTTGAAATCACTTGTTTACAACTGGCT CTAAATCAGCTTTCTGTTAAATTTTCAGTATAAGAAATTGAAATTATAAGAATTATGGGT TTATACATGTAAGTTGTTTTAACATATTCAGTCATGTTCCTCTTTGGTGAGAAGTAGAAG AAATTATTTGTTTAAGAAATATATAGGAAAATAAAGCAGAGCTATGAATGCATAGCAAAG ATGGGAGTACTCTCTCTGGTGGTCTGGTTGGCCTCCTACCAGGAGGTGAGTCTCTTTAAT TCAATATCCAGTAATAATCAATGTATTTGAAAAGCACATCTGTACATAATGGACAAATTG AAAATGCTTCCATCTTCCTGCTCCTTGTCTCAGAAAAAAAGTCATCTTTTCAATCTTTGT GCTTTCTTTGCATTTTTTGGGCACAATTCTAATTGCACGCTAGTCACATTTTGGAGTCAT TTTTAATTGCTTATCTTCTTCTTTTTCCTGGAATGTGAAATCCTATGTCTCATTCATCTG TTTTCTCCTATCAATGTCTAATATGTGGTAATATGAAATTGGGACCACTAAGAAGTATCA CTTGAATAGTGAATATGGGAGGGGAAATGCTTATATGAGGAAAATGTGCTGGACACCCGT ATTAGTCCATTCTTGCAGGGCTATAAAGAAATACCTGAAACTGGGTAATTTATAAAGAAA ATAGATTTAATTGGCTCATGGTTCTGCGGGCTGTACAGGAAGCAAGGCTGGGGAGGCCTA AGGAAACTTTTAACCATGGCAGAAAGTGATTCAGGCATGTCTTACATGGATGAGGCAGGA GGAAGACAGTGAAGGGGAAGGTGCTACATTCTGTTTAGCAACCAGATGTCATGAGAAGTC ACCATCATGAAAGCAGCAAGGGGGAAATAGGTCCCCATGATCTAACTACCTCTCACCTCC TCTAACATTGGGGATTACAATTTGACATGAGATTTGGGTAGGGACACAAATCCAAACCTT AGCAACATTGTTTTTTTTTTTTTTTAAGTTTAGACCTGGTGTTACAACTACATAACCTGG ATCAAGTCATTTAACTCTCTAAGGTGAGAGTTTCCTATTCATAGGAAGAGGAGAATAGCC ACCAAGAAGAAGCAAAAGAAAGATTATGTGTGGACTGCTTTCAGACCTGTAAAGAGCTGT TCAGTTTATGTTATTATGTTAGCATTTCAGCCAGTGGGAGTGCTCTTTGGGTCTCTCTCC ACTCCCTGAACATGTTCAGTGAAAACTATTGGTTTATCTAAAGTTTTAAGCTGTGGGTCT CATGTACAGATTTCTTTCACTTCATGTCAACATTGATTTCCTTCCCTCATAAATTCAAAG CACTAAAGGGTCAGAGTTAAAGGTGTATGATTGCATCTTGGAAACTACAGTCTCACTATA GTCACAACACATTGTACTACAATGTACAAAAAATGTCAAGAATATAATTCAGAAACTGTT CCTCAGCTACTTTAATTCTTCAGTTGTGCATTGGGAGACGTGTTAAAATGTCCATACTGA GCCTTCACCTTTGTCATTTGTAAAAAGGGATGGCAAGACCCACCTATATGGTTGTTATAC AGATAAATGAGATAATACATCTTAAACACCTTGTACAATGCCTGGTCATCATAAGACTTG TAATGAATAGTAGCAATGTTGACCATTATTCAAGGAAGAGAGAGTTTAGTATGGACTGGA AGAATACTGGGGAGCTAATGTGTGTGTTAGATTTGAGTGCAGGAGATGAATTTGCATAGA GGTAAATCATGAAGAAAGGCTCTGAGGTGACTGAGCTAATGCAAGAATCAATATCAACCC AGTTGTTCAAACTGAAACCTGGGTATCAACTGTAGCTTGTCCCGTACCCTCATGCTCATT CCTAAAATATTCAATTCACTACCAACGTCTATCAATTCTAACTTCTTTCAGATCTACCTA ATCCTCTCAAATTCCACTGCACTTTTCCATTCCCAGTACCTCTCTCCAGCCAGGATCCCT CCCACTACTGTCAGTCCCCAGGGTGTCCACCATACTCTTGCCCTCAGGTCTTTGAACGTG CTGCTTTCTTAACATAGAGCAATTAGCCCCTGGCTGCCTTTCCTTCCCCAGTTGAGCACA CAGCAAGCACACATACATTAACTCCTAGACTCCTTTCCTCCAGTAGGTCTTTATCATAAC ATTGCATTTCCTGTTTATTTCTCTCTGTCCTTCACTAGAATGAAAAAACAAAAAGCACTC TGCTAACCATCAAATAAGAGCCCACTTTCCACAAATTCTCAGCACACACCAGACAGTCTT CTTGCATTCAAACTCTGCCCTTCTTTCCCATACTGTGGATAAATTGTCCCCATTCCAAGA CCAACCTTCCTTCACATACTCAATCCCATCTCTCTTACCAAAGTGAGGACATTACTGCAG ATATTCTTCTCCTTTTCTCCTACATTATCATTTCTCTTTTATAACATCATTTCTGCAGAT ATGTAAAAATACATCCCATCTTCAAAAAGAAAAACAAAAATCTGACTGTACTTCATATCC CCTTCTAGACATTGCCACATTTCTCTACTTCTGTTTACAACAAAACTCCTGGAAAGATTT GTCTATACTGGCTTTCTCTACTTCTTTTACTTCCATTCCTTTCCTAACCACTCTAAACAT GCTTGGGTCCCCACCACTGTAACAAATATAATTTGTGTCCAATAACCAGTGATCTCTGTA TCACCGGTTCCAAGGGTGAGATCTCAGACTTCACCTTTCTGGATTGATTGACACATTGGA CTCAGTTGGTTACTCCTCACTTCTTGAAACTGTCTTCACTGGGCTTTTTGGACTCCTGAT CTTGGCTGTCTCTCATCATATTTTTTTTTTTTTTTGGCTTTTCTTTACTGGTTTCCCCTT ATCCCCCAACCTCTTAAGGTACACTGTGTTTCCTCTTCTCTATCTGTACTTTCTAACAAA CCAGTCTCATGGCTTTAAGTGTGAACTATATGTTGATAAGCCCCAGATAACTTAATCTCA GACCTCACTACTGAACTCCAGAGTTACTACCTATTTCACATCACCAAGTTCCTATTGAGC ATTTCATGGTGAACTTATCTAAGATGAAATGTCCAATTCCCACCTCCTTCCCAAAACCAT TCTAGACAACTCCAGTTCAATGCAACTCCATTCTGCCAATTGCTTAGGCCTAAAATCTTG TAGTTGTCTATCAGTAGTCTTCATCACATGAAAAACCTTGGCTTCTTTTCTTTATCACAT CCAATTTATCAACAGATATATCTAGGAGCCAACCCTCCAAGCCATTGTCATCTCCCATGT GGATAACTGACGTAATCTATCTGGTCTGTTTCCACCCTTACTCCCTGTAATCTTTTATCA AGATGGCATTCAGTACAAATTTTTTTTAATGTAAGGCATGCCATGTCACTCCTCTGTTAA AACACTTTCCAGTGACTCAATATCTCTAGTAAATAAAAGTCAATCTATTTTTAGTGACCC AGCTACCTCCCTGACTTCATGTCCTACGAATCTCCTCCTTGTTAGTTTACAAATCCTGTA GGACTCTCTTTTGGCTTCTACTACATCTTCAAGGATGCCTTCACTGAAGGGCCTTTGCAC TTGCTATTCTCTCTGGCTGGAATTTTCTTACTTCCCAAATCTACATGACTCACTCCCATT CTCTCATTTTCCTCAATTCTCTGCTCATTTGGCACCTTTTCAGTGAAATCTTACTTTATC ACCTAATTAAAATAGTATCCTCATTTCTACCCTTGGCATTTCCAGTTATTTACCCTGCTT TATTGTTTTTCCCCGTAACAGTTACTGCTTTCCGATATACAATGTTAGTTTGTTTGTTTG TTGGCTATTATTATCCACATGAAGGCAGCTTTGTGATAACAGGGATTCTATAGGTTCCCC CTTCCCATCATTTGTCTTTATCCCCAATACCTAGAATAACATCTGATACATGGAATGTGC TTAAGAAAACATTTGTTAATTGAATAAATGAATGAATGTTCCTCTTAATTGATTATGGGA GACTAGGATATCAGTCATTTCTTCTAGCTCTGCAGCTAAATATACTAGTGTAGAGTAAGA TTCTTATGGTTGTAAACTTGGCATGTTACATTTTATATCTTTAGACTACTTAGCAGATTC CATGGTTGAGTTACTTTTAGAGATTTTCTTTCTTTTCACGTTCAGACTTCTGCCTTTAAA TATCATAAACTTAAATGAACACATAGACATCAGCAGCTTTAAACAGTTCTGTACGGATGC CCTCACAATAGTGGTCTAAGCAATTGTTTTGCTTTTAGCATAGCTGGCTCAGTAATTTCT ATTTATGTTCCAAATGCCATTGAAAAGCCACTGAATATTACTCAAAGTATGCCAATATGA AAAATATCATCAACTGCCATTTTATTTCAAGCTGGGCTTCTGCACAGCAAACTGTTCCAA AGTTGGTGAAAACCAAAAATCCAAGTCACCTTAAACAGAAAGACAGATGTAAAACAGTGA GTAACTTTTTAAAACAGAAAACAAACTTAATGTGCTGTATATTCTTTTATTATTTTCTTA GCATTTTTTTGACCTGTTATTTGTATTGAGTTTTTTCTGTTATAGTGAAAACTGTTTTAT TATTTCCACAGATAGTTTAGTAAGATATGAAAATCTCATTGTAGACTGCCATGGTTGGCT TATTTCTTCACTTATTCTCATGATGTCAAAGTTCAGGCTTTGGAATCAGGCTTGTTCATT TGGAATCTAAGCTCTTTGAATTTTCATCTCAGTAACATCAGACAAATTGCTCAACATCTC TAAGACACAGTTTTCTCATGTTTGAAATGGGAATAATAAGGTTGTCATGATGATAGAAAT AAACAATTCCTATATAACACTCAATACATATTTACCAGTATTTCTGATGTTATTAATGGG TTCTCTTATGCTGTAGGAAGAGCTGTTTACCAGTAGTTCATAATTTGGAGCTGGATATAT TATCTCCAAGATATAAACTTTTTGTTCACTTTCTAAACAAAACCCATTAATCTGAATATA TGGATTCCCGCCCCCGCCCCCGCCCCCGCCCCCCCACCCCCAACCCGCCAAAGTGCAGTG CTTGCTCCTTTCTCTGAGTCATGGTCTGACATATTTCTTTGAACTTAAAAATTAAGTTTT TCATTTATATTACATTTGCTGGAAAGTTTGTTTTGTTTGCATAATATAATATTTATTTTA AGAGAAGACACTTATATTGTGAAAGCACTCTCTCCAGAACAATACACAACATATAGGATG ATTCTGATGATAAAGGAATTAGACTACACATCAAGTAAGTTCATTTAAAATAATGAAGAA ATTATAAGCAACAGAAAGTGTTCTACATATTCAACCAAAAGGATTTAAAAAGCAGATTGC TTACCACAAAAAGTAGAAAACAATAGACACAAATCTAAAATTAAGATAATTTAAATAGTT ACAATAACTTTGTCTATAAAGATACAGATTGTAATTTTGTACTCCAGGTAGCATAAATCA ATCCAAACTATATTTTAATTGATATTGTAAGAATTTTTTTTTATTATTATACTCTAAGTT TTAGGGTACATGTGCACAATGTGCAGGTTAGTTACATACGTATACATGTGCCATGCTGCT GTGCTGCACCCATTAACTCGTCATTTAGGATATTGTAAGAATTATAATCACACAAACCAG TTAGAAATCAAGTCTAACCTAAGCAAATTTAACCTCTTCAGGCCTTTATTACTATTGTTT GTAACCTCCATGTTTTCCTTTACCATTTTCTTCCATATTCAGCTTATAAATAATTAATTC CCTATACTCAGAAGTTGTATTTAAAACAAAACAACAAAAACACATTAATAACTAGCAGAC ATCAAAGATTTTAATAACCCAGACCAGCGAAGAATAAGAATCCAAAATAGCTTCGTTACA ATAACAAACTGATATATTCTATTGTAACCTTTAGTTTGCTGTAGATGGATACTTCATTAA AAATAGATATTAGAGGTAAAGTTATGTATACAACACAGAGAAATGTAGTTGACTTTTCCA AATCTGGTAAAATGGATGTTTCCCCATCTTTAGGTGAAAAAAAAATTCTACTAATCAGAG ACAAGAATATAAGATATAGAGCTTTGCAGAATAACACTCCAATCATGTTTGCTTCATGAA TATATATTAGTGACTTCAAAATCTAGGGCATACACTGTCTTTTAAATGCATTTTAAAAAA TGACATTAATGAAAAGAAGGAATTATGGGGAGGTAAGACCTTGTTCTGTCAAGTTTAGTA CCTGTTCTAAAAACAATGATTCAGAGTTTTAAGCTAAAACTGTCTCTTCTAGTTAAAATA CCCTTCTGACCAAATAGTGATGCAGAAAACTTTTAAAAGTCAAATGGAAATCAGCTTGGT AAAACATTCTTGGTGTTCTTAAGTGACTCTCCAACAAATATTTATCGAGCACCTCGTTGT GTCAATACCATGCTTTTGCAAATGGCTCAGTTAGTTATCATCAATAATAGTATTGTCTAG ATTTTGAATAATAATAATATTACTAATAATACTACTAATAATATTCTTAAAGGGTCTAAA AGAACTTTCCTCAGTCTCTTTCTCGAATAATGTTTTTTCCATGTGGCAAAATGTTTCCTT CCCTGAGCTTTTTTTCGGGAACACAGATAATCATCATTGTTCCTTCCTTGAGTTTATAAA CTAATGATTCTCTCCATTTGCTCCACCACTATTTAGCTCTCTGCTGGGCTAATCTAAGCA TCAGAATCCTTGGTGGTTAATAAATGAGCATCTTAGAAAGAATTCCACTGGGAACATGGT ATTCAAATCAGCCCTCCAGGGCATTTTGTTGCAGTGAATTCCCACAGGTACGTGGCGCAA GATGGGAACTTCTCTTGGGAAGGTTATTTATGTGCTCAGCCTGTCTATACAGAATTCAGG TATAGAATACCTGAAAACACTCAGAAGCAGCCGTCAACCCCCAGAAGGAACCATTTCCCC ATGTATACAGTTGAGCAAGTGAAAGCCATTCTGTATGTAAGAAAAGTTGTCAAGGGGCAA TATTGAGGTTTAATAGTGCTCTCTAAGTCACTTGAAAACCAAATCTTAAAAATGATGTAA TGTATACATTTGGCCTTCATTAGTGTTGTATTAAGCAGGTAGGCATTATCTTGGTCTAAC CATTAAGTACAAATGCTTAAGCAGCTTAAAGCCCTGAAGTCGGAAGCACTTAGAAGCTCT GGTAAAATTGTCCATAATACAAACTAATCTAAAGCATCATAAATACTTAAAGATTGCTTA GCATATCTTTACTGTCATTGTTTTGCAAGCAGCTTACTTTCTCTAGGATAATAAAGATGC AAAGATCAATAATATACTATTTCTTAGTAAAGGAATCAAATGCATATCTATTTTTTCCTC TCTATGAAGGCTGTCGATTTTTTCTTCTTGTTTTTGAACAGTATCAGGCCTTGCTAGATG GCATGAATTACTCAGAAGCTTACAGACATCAAGGTAGGGGGGTCCTGAAAGGTGTGGCAG GGGTCGCTGAGCAGTGAGAATAGCCGGGAAGTGAGTGCTGAGTGATGCAGTGGAGAATGT ATAGAACTGGAAGGGAGAGCCTGGAATCAGACGTTAGGTTGTTTGAATCCTGATAGAAGA ATGTATTGGCTTGTGAATTAAGGCAAATTATTATAAACTACTGAAGTTATTTAAATCTCC CCTCTGAGAATTCTTAAGGGAATAGCATGAGATAGGCCTTTGAAAGTGCAAAATGTAAAG CAACATAGTTATTGTTGTTGTCGTTGTTATTTGTAGGGAAGGGGTTAGTTTGGTTTGGTT TTTTAAATAGAAGGAACAGGGATCTGAAACAGCAGCCATGCTTGCTGTCTTTCCCAGCTT CTTTTCCAGTCTGCCACAGAATGCCTCATGCGGTGACTTATACCTAGTAGGTGCTGTCTG AATATTTAAGGAATGAATGAAGCTTTTTTCTCACAGTTCTGAACTTTGCAATGTGAATTA TGTACTTCCTTATAATGATGTTATTTTTATATACGTCATCTCACCTGTTAATTCATGGGC CTCTTGTCGAGTACATATCAGTCACAGTCATGTACCCATAGTACCCCAGTTGGTGATCCC TGAATATGCATTAAATGAACTAAATGCATGAGATATAAACCCATCAAGCTTAATAGTTTC ACTTTCACTTTTTAATTACTTTTTCTTTCTGACAATATCTTCTTCTCTTCTGAATTACTG AAGTGATTTATCATGATTATCCAGTAACTTGACTAATTTGAGAATTAAAGCAAAGTTCTG TGTCTTTGGAACTTACCATTTACTAACATCAAACATGTAGTAGCTCTTACCATGTGCCAG TCACCCTATTAAGGAGTATATTTGCCACTGAGTTTGTATAATAACCCATTAAAGTGGGTA TTATTATTATTCACTATTTCCAAATGAAGGAATTGGGAATTAGGGAGTAACTTTCACAAG TCCCCAAGGGGGTAGCACTGGGATTCTAACCCAGGTAGGCTGTTTCCAGGGCCCATTCTG GGAAAAAAAGTAACATGATGACAAGGTATTATGTGCTAAGTGTTCATGGAGAATTTTTAA AGTGCCATCAGATTTCAGGGAAATGAAATCGCTAGGAATTTGCTATTTGAAAAGATTTGG TGGAGTCAGTAGAACTTGAGTTTGAACTGCCTAAGAGCAGTAATAACAACTGGAAACACT TGTATTGTACTTGACATGTGCTAAGGACCTTTGGTTAATAATTAGGTCATTTATGCCTCA CTACAATCCTATGAATTAGGTACTATTATCATCCCTTCCTTTTACCAATGACCAAACTGA AACACAAGCCTTAAATAACTTGCTCCAAGTCACCCAGCCAGTATAAGGGATTTGGGGAAC AGCAGAGAGAGAACAGGTTGTCCAGATGAAGAGAATGTGTAACCATGTAGGCTTTGGAGA GACTCGAACATATTCTGCTACCTGTGGATTTTCTCTGGGCAATGAGCAGGAAAGCACTGG AGACAAGTTAGCTCCCACTACAGACAGATTGTAGAGGGTTTTAGATGTGTTGGCTGAAGA ATTTATATTTGATTCTATGCGGGCATTGGAATACTGTTAAAATTATTTATCAGCATTTAT TGTTTAGCTTTAGATTATCTATAATGGTTGCAGCACTGTGTCAGCTTAGACACTTTTGTC TGGGAAGCCTCCTGACCACCCTTTCACCACTTTCTCCAATTCTGGAATAGATGCTTTTCT GTGTTCCCTGAGGACCCAGAAATCTTTGTTCTTGTAGCTCTTACCATATCTTTGTGCTTC CCTTTTGCATTAGTCAGGCTTCTCCAGGGAAACAGAACTAACAGGGCATGTGTACGTGTG TGTATAATATAACATAAAGAGATTAATTGGCCGGGCATGGTGGCTCACACCAGTAATCCC AGCACTTTGGGAGGCTAAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAACACCAGCCTG GCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCA GATGCCTATAACCTCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAATCCGGGAG GTGGAGGTTGTAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTAGGTGACAGCGAGAC TCCGTCTCAAAAAAAATAAATAAATAAAAATAAATAAATAAATATAGAGATTTATTATGA GGAATTGGCTCATACAATTACAGAGGCTGACAAGTCCCAAGATCTGCAGTTGGCAAGCTG TAGACCCAGGAGAGGCAATGTGTAGCTCCAGTCTGAGTCCAAAGAGCTGAGAACCAGGAG AGCTGATGGTGTAGTTCCAGTCCAAAGACCAGCAGGCTCAAGATCCAAGAAACAATGATG TTTCAATTAGAGTCCAAAGGCAGGGAAAAAAACCCATGTCCCAGCTTAAAGGCAGCCAGA CAGGATGAGTTCTTTACTCAAGGAAGGGTCAGCCTTTATGTTCTATTCACTAACTGGATG GAGCCCACCCACATTAGGGAGAGAAATCTGCTTTACTCAGTTTACCAATTCAAATGGTAA TCTTACAAAAATACCCTCACAGACACACTCAGATTAATGTTTGAGCAAATGTCTCTGCAC TCTGCATCCCATTCAAGGTGACATATAAAATTAACCATCACACCTTCATCATTCCACCCA AAACCAATGGGCTCTAGTAAAAGAGAAGAAGGGCTTCTCTCTTATTTTCCTGAGAATGCC ACAACACTTAGTACAGAGCTGGAATGCAGAAGGTGCTAAACTTAAATGTGTTAGCCTCCT GAATATGTTCTGGACAAAATATGCTATAAATCAATTTTATCTAGTTTTGTTTTATTCTTT GATATCTTGAGTATATATATTTGATGCTTCCTATGTACATCACAGGTAGGGATCAGACCT TTTTGCCTTACAGCTTCTGTTCTGAATCTGATTCCTTACTAAGGAGACTCTATTAAATAC TTGTTGATTACAGTCTTTTTTGTGTGAGGAGGAAAATAGTACATGCAGACATTTATTTAC TAGACTTCAGTATTAGCAGTCAATCATTATCTCTTCATAGCAACATTGTCTCACTTTTCA GGTCTACCATGCTCCCAAAAGTCACTGTCAGCTCTGACCATACCTGCTGTTCACCACTGC TCACATATCCCACATACTTGCCTCCCCTCCTGCCTTTGCTTATGCCATACCTTCTGATTG GAAGCTTTTCTTCCTGCATTCTTAACATGGAGAATGCCTACTCGAATTTCAAGGCTCACA TCACTGAATCTTCACCTTCAGCCTTTCTCATGTGGAAGAATCCATTGTGTCTTCAAGCAA GTTCCCATAACACTGGGTATCTACTTCTGCTAGAGTTTATTCAAGGAGTATTGCCTTCCT TGCCAGTCAGTGAAATTATAGGGGTCAAAGACGAGGTCATATTCAATCTCTGTATCTTAA GCACCTAGTACTCTACCTGACACACAGTAAGTCGTCACTAATTGTTCGATGAATAAACTA ATGTGTACAATAAGATTATTAACAATGATATTCATGCCTAGTATTCCCTGGCCTCCTTCC AGGCCATTTAAATTTTCTTCTTTTTTTTTTTTGTCTTATTGAAGAGATGGGATAAACAGT CATTCTTAAAATTTTATCTTTGATGGTGAATAGAGGTCCTCCAAGAAACAGCTACTGTAA CAGGATTAGATATGAAAGAGATTTATTGGGGAGAACTGCTGTGAGGAAAAAAGAAGAGGA AGCTGGGGGAGGCTGGGAAATTTGTCAGATCACCATGCAGGTTTAATCCTTGTGAAGGAG AGAGGGAAGGAATGAAGGTTAGATATGAAAAAGTGTTACACTGTGGTGCAGTTTTAAGAA TGTTTCAAACAGCCAATCGGGAATCTTCCAAAGATCGCCCACCAGAGGGAGCTTTGTATC TCTCAGGAAGTGGCTGCGTTAATATCCTTGCTGAACTCAGTTGTTCGCTGGGAGCAACCC TTAGCAGTATGGACTTCCTAGTCAAACTCAGAGATGGATTTCAGAGCCCAGAAGCCAGGG CCCTTGGTCAGTTACAATCCTTGCAGTTAGATTTCAGAGCCCACATTTTCATGGTGACCA CAGTGGCTTGAAACCCTTGAGGCAGTAGGGAATGTCCTTTATTCCCTCTACAGTCTTGCA TCTAAACATATTTTAAATACAAAAAGCTCTCTTTAAATAATGAAACTATAGAAAGTGCAT GGAAACCTTAAAACCATTTGAAATTATTTAGAATCCTAGGTAAGCTTCAATTGTTAGCTA ATTCTGACATGATAGAGAAAAATAAAATACTTAAGTGAACAAAATTAAAACACTACAGGA AACTGTGGGCACAAATATGTTTCAAAGAAAAATCAAAGGTATCTTTTTGGCTTGGAAGTT TCTAATGAGTAGATGTTCTACTAAGGTCATAGTTTTTTGGATCTTACAGTTTAAATTCGA ATGGCTTCCTCAGAAGAATCACATTTGACAAATTGTTGATGCTGCATATCTTGTGAGAAA GAACATGTAAGTCTGTTGTATAGAATAGAGCATATCTAATTTATAGGAGTTTTAAATGAC AAGCCTTTTCTAAATTCCAAAAGGCTTTAAAAATTTGCATTCCTATAAATAAACCAGTCT TTCTTAGAAGCAACCTTAACTCTAATAAATAAATAAAACCCAATCGTTATTTCATATAAC ATTTTTCATGCCAGAAAGAAATGATTCAAGATAATATATGGCATAACTTATAGAAGGCAG TGCTATTAAAAACACGTGATTGGTTTCCCTGCTCAATCCCACTCTAGTTCCCAGCCCCTG CATTTGTCCATGAGCTCACTACTTCTCTCTGGATATTTTCTCATGGGCTTCATCTTGTTG AAAAAGGCCTTTGCATTTCCTCCCCACCCATAGTAATCCATTACTTCCTTGAAGATACCT TGAATTGGGAAGGACTACTCTTTTCCAAGAAGTATTTCCTAAAGAACTATTCTCTCAATT ATCTCTTAGAGACTACAAAAGTAATATGAAGTATTGTCATTAAGTATTTGCATTCCTTTA GCACCTATATAAGTATACTCTACACTCTACTAGGTACTCTCTTACATGTTGTCTTTTCCT TAAGATCTTGTCTCACGTATTAAATAGAAAAGACTTCAGGGAAATAGATGATTCTTTTAT TCCTTTAGTATTCATAAGCATGTAGTAGATCCAAAACAGAGGCTTTTATTTTGTGTTTAT TACTTTTTAAAAATCAGACTAAGTGCTTATGATAAGAAAACCCAGGAATTGAAGGTCTTT TATTCATTGAATTTCACTGCCTAGAGGCAGTCTCTTTTAGGCTTTTCTGTTTTTGTTCTT ATGGTGAATTTATCTCCATAACCTCTCTTTCAATGAGGAAGTTTTAGACAATATGTACTG ATTCCCCACTATGAAATATGAGGATCTAATAATGGGTGCAGCATTATTTTCACCAGTTTA TCTCCTTTTTTCATTGTTTGATGATTGTTGTATTAATTTGTCTTCTGTTGATTATTTTCG TAACTTAAAAAAAAGATTTTCTTGATGTCTTGTTCCATCAACATCAGTGAGCACTTAAAT TCTCAACATGAGAATTTTAATGACCCTAAACTTTCTTCTACTTTCCCTTCTCCCATTCCA CTGATCATCTCAGTTATTCTTATTTTTATGTTGTTAGGATTCTTAATAGTTACATTTTGT GCTATAACCATAACCAGGGTTTCATGTTTGATCCATAGGTTGATTCTAAAAGTTAAAATT CAAGTAGACTGGGGTTACTATGACTACATTGATGTTGGTCATGGATGAAATGAGTAATAG GATTACATTTCCTTCTCTATAGAACTATGGTCTTGACCCTTCAGTCACTCAGAGAGTATT TCCAGCACCAAAATTAAGTAGATTATTTAAAATGACCTCAAATTGCTTAAAATAATGTCA CATTATTTTTTGGCTCATATCTACCTCATATTAATCTCTATACTTTTTTGTACAGTTTTT TCTTTTCCTCCTTGTTTTGTTATTGACAATGGAATGTATGTTTATCATAGTCTAAAGTTC TTCATCTTCTCAATTACAAAATTGGTTGTATATTGTCACCATTTTTCCTGTTTTCTTCCC TCTTGAATTCATGTTGGAGCAAAATTATTTAACAACTAGCGTGACATCATCACTGACCAA TCAAGGCAGAAGTCATTTTTAAACAGCCAACTGGGCATTCCTGTGTGTACACACTAACAG CTCTGCCTAAGCCAGCAGCACAGATGCCACACTAGGTTTCTACCTTTCTGTTCCTGTAGA ATGGCCTAATTATTTCTTGACTCTCCTTACTTCTGTTTTCTCCTTCATCTTTCTAGAATA CATCTTTAGCTTCCTCCAAAGAAAAATGTGGAAAATTAACTTTAAAAGAGTGAAAAGTCT TTTACCTTCATTCTGCATTGATGACTTGGCTTGGAATATAATTCTGGGTAGAAAACAGTA TTTCCTTGGCATTTTTAAAGCATTACTCCATTGGCTTTTATTTTTCATTTTTAATATTTT TAAAGGTGGGGTCTCTCTCTGTTGCCCAGGCTCGAGTGCAGGGGTGTGAACATAACACAT TGCAGCCTCAAACTCTTAGCCTCAAGCAGTCCTCCCACCATGGGTTGCAGTCCTACCTGT AGCTGGGACTAGAGGTGCACACCACCATGTTTGGCTTTCAATGGCTTTTGGCCTCCAGTG TTGCTGATGGAAAAGTCTGATGACTTCTGAATTCCTGTTCCTTTGTTGGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTTTTACTCTAAACCTTCTTGGATCATTTTTTTGGATTTA ACTTTTTAATTTATATCTCCTAAAGATGTATGATGTGTTTCGGTGCTAACCTTTTTTTTT TTTTTTTCCCTCACTGTTTTGGTTATTCTATAGGGCCTCTCAATCTGAAGGTTAATTTAC TTCTTTAGCTGTGGAAATTTTTCTTTTTTATTTCTGACAATCGCTTATTCTGTGTGTTCT CTGCTCTCTTCTTTGCAACTCTACTAGATGTTCTTTGGATGTCATGGGTTGAATCTCTGT ATTATTAACCTCTTCTCTCATAAGTGTGTATGTGTGTTTGCATGTCTATCTTTCTTTGAG TTTCTCCTGTATTATTAATTAATTATAATTTTAATACCATTCTCTGTTTCCAGAATTATT TCTGTTTCCTTCAAGATCAGTTTTCTTTTTGTTTGTCTTGACTTTTCTGAGGCATGCTGT AACTCTTCCTCCAATATCTCATGATTTTTGGTTATCCATTCTTATATAAGAGTCAAGGTT TGGGAAGTTGGCATGGCTTTTTTTTTTTTTTTGGCCACTATATAAACACATCATCCTATA ACTCTCCTTTTTGAATGAGAAGCCTAATTCAGAGCTCGTTACTGGGCAGGTATTCCCACC TGGCAGGGAAACCTGCCAAAGATCAAACTGCAGGCTGCAAGCCTCAGGACCACAAATGCC AAAATAAGGAGGTGCCAACACTCATAACAGAAACTTAGGTCATCCCTAGACAGTTTATTT AATTTATTTCACAAACAGTCCTCTGACTTATTTTATTTTATTTTATTTTATTTTATTTTA TTTTATTTTATTTTATTTATTTTGGCTGAGAATGAAGGCCAGACTGCCAATCACTTCGAG TAATGGAAATGGAAGGGCAATTGTTCCATATAATATGTTCTCTTTCTCTTCCTGTTTTAA GCCCCACATCTCACCCTTACTCTCATGTAACCCTCCAGCCAAGAGCCTGCAGCCTTTCAG GTTTCTAACCTTCTTACCTTCTCAACAGTCCTCTTATAGCACATTCTGGTGACTGCATTT CTGTTGACCTATCAACATTTCCATTTGTTTTCTCCCATAAATGTGTTGAAATCTTATATC TTTGTTGTTATATGTCTATTCCTCTTTGTACTTCCACACAATTATGTACATATAAAACAC TGTTACTTCAGAGCCCCCAGTAGAGTGAGGACATGAATGACCAGCCTCAGTCTGCTATCT TCACCCACAAGTCCCTTAACTGCTCTTGGAATTTATATTTAGCAGGGATTTTTTTTTCAG AAAAATAATATGATTAGTCTTCTTCTAAAAAAAAAGAAAAATGAATTTGTTTGATTTTGT TTATATTTTGCAAAACTTGATGGTTATGTTCAAGAGTTTTCAAGATAATTGAGGATTTTG AATCAGTTCACAAATGTGTTAAGAGTTGTCGAATTTTCATGTTGTTGGCACAGAACTGTG AGGAAATGAACCAATCCTAAATTAAATGTCTACTTTGCCCTGCATTTTCCTCAATTAGAT ATTAGGCTTAACTTGTGTACTTGGTTAAATGGTTATATATACATATATATGTGTATGTGT GTGTATATACCCATAAATATATATATACACACACACACACAAATTTTATTTAAAATATGG TCTATGGGCTACTGCATATCAATATTTGCTAACTGTCCATGACAATATAAACTTTTACCA GAATGTAAATCAACTAAGTTACTAAGCATACTTTGCAGTTAACATTTTTTCCCAGCAAGA CATTCCCAATGAAAGAAGGAGTATAATGACTCACATTTTGTCAAAAAAAGATACTGATCC AATCACAGACAGGTAACAGTTTTCAGATCAGCACTAGTCCTCAGTTCACATCTTGAGAAC ACTTGCAGACATCAGTTAGAACAGTGCCTGGCAGAGAAGGCATTGAATAAAGTGCTAGTT GAGTCTGACACGTGGACTTTTTGGAATAAGTTTGAGAACTATTATGATCATTTACAGATA CGATGCTTAATTGTGTATCTCTTTCTTAAAACAATAGGGGAAGTTTCAATCATTTCTCAC AGTGGAAGTTTTGTTTTCTTTCAGTTTGACAAAATCCCATAAACCACTTTGGTTTGTTTA ATAGAAAGCAATCATTTAAGTTGCCAATGAGATAATATCCAAAACTGTTTCAGACCTCTA CTTGTTGCCAACCCTTTCCTGTCTGTTCTTTCTCCCTACGAACCTTCATCCTGAGACTTC ATGCTAGCTGATTCTAATTAACACCCTGGGATCTGCAAATCTTTATGTGTAAATTGCTAG TGAGGTGGGTAGTGAATTTACTATATCAATATTTGTCTGCTATCATGAGGCCCTCCAGAA TTTAAAAATGATCTCTCCATCTCTACCTGCTGATGAAAGGTAAGACATTTCTGTAACACT ACTGAGAAGGTACTACCTCCTGAATATTCACTATTGCATAATCAGGCAATGGTCAGTCCC CTTCTGTTGGCCCTCAAAATTCCTTGATTCTCTTCCCAAACACTTTTACCTGAAGAGAAG GCCTGCCCACATTATAGCTCACTGTCTGATGCTAATCCACCCTTGGTTCTAGTTAGCTTC AGATCCCAACGATTATATTATAGCACTGTCCTTCAGTCTCATTCAGACCAAATTCCTGGA ATGGCCTAGTTTCTAAATGGTGCTTGTCTTAGACTGTTCAGGCTGCTATAACAAAATACC CTCAGGTAGGTAGCTTATAAACAACAGAAACTTACTTCTTACAGCTGGGGAGGCTGGCAA GTCCAAGATAAAGGTGCTGACAGATTCAGTGTTTGGTGAGGGCCCACATTCTGGTTCATA GATGATACCTTCTTACTGTCCTCACTTGACAGAGGGGGTGAGGAAGCTCTCTGACATCTG TTTTATAAGGGTATCAATGCCATTCATGATGGCTCCACCCTCATGATCTGATCACCTCTC AAAGGCCCCACTTCCTAATATCATCATTTTGGTGGTTAGGTTTCAACATATAAACTTTGC AGGGACACAAACTTTCAGACCCTAGCAAGGCTCTTACCATTTTTGCCTTTTACTCTGAGA GTAGCACCCAGTCTTTCCCAGAGATAACCTTCCCTCTGATTTCTACCACTCAGTTGATGC AACATTTAAGAGGCTATGTACTAAATTCCAACTTGATTAGAATCTCTAACCTTTTTCAGC CATGAGTGCTCTGTCTCCTTTTGAGACCTACCAGCTCTTCTTTCCTAGGATGCCATGTTG GTGGAGGGCATCACTTGGGGCAACTCCTAACAGAGCCAGCTCCAGTCCTGCTAAATTTCA ACTTGCAAGCTCCACCCTGTCCAATCCTCAGATAAAGAGCACCAAACCCACATGGGTTAT GTTAGTGCAAATAACCTTGTTAGTTTGTCACTTTATTCATTTTCAATTTTCCAAGTACAT ATAGAAACATTATTCTTTTGTATTTAATGATTACCTTGTAATGAGCAAGTCAGATTAATT GCTGTATTGCCATTTCAAATATGTTAGCCGTATTAGGCCTAGACCATTTCAATAGATCTG ACCCAGAGACTTGGTATTTTTTATCTTTTCAATCCAATTTACACACTGTTGCCATGTTAG CTTCTTCAGTTTGCCACATGAATCCTCATACTTGTGCTGAAGAACCTATGGTGGATCCCT ATGGCATAACAGATGGAGTTCAAGAACTGCTGCCTGATCATTAAGCCACATCATCAACTC AGCCATTGACTCCTATACCCTAAGCTGTCTTTCAGTTATTCATTTGCATGCCCTTAATTG TTGCCTCTAATTTTGGCATATTGCTATATCTTTCTTTTGCTTTCTACTGATTCAGTTTTT ATGCATCTTCTACAGCTCAGTTCAAATGCTGTCTCTTCAGAATAATCTTACTTGATAATC TCAGGCAAATGTTATCTTCCCTTCTTTGGAGCATTCATTTTATTTTCTGTCATTTCTACT CATTTGTTAGTATACTTATCTCCTTTTTTGAGTATTAGCTCCTTGAGGGTAGGTGTTACC CCTTTATGCATCAGTGTACCATCATAGTGGCTAACACGATCTCTTTCATGTGGATAATAC TCAATACCTAGTCACTGAATAAATTATTGATTGTTACAGAAGAGCAAATAAAGTAACTAT TATAGTGGCCACTCAATCAAGGTGATTTGTGAGAATTTAAGGAGAACCAACATCAGGAGA ATTTGGGCCACTCTTGATGAAGAAAACCTAATTGTGATGATACTTGAATATCCCCACTCT CAAGAAAATAATTTACCTAAAAGTATTGATTGGTTTACAGATACCTGCAGAAACCTTTGT TGTATATATGCAATAATGGTATTTGGACTAAAGAGGTAAGAAATGATGTTTTATTTGTAA ATCTTCAGCAAGTCTATACTTAAGAAAATTGGCCTAATAATTGATTCACTTCATGGAAAA TTAAATAGCCATTAAAAATTATACTTCACAGGTTGCAGTAACATGGAAAATGTTTACATA ATGCCAAGCAAAAAAGTAGAACAAAAATTATATATATACTATAATCTGACTGTGTTTTTT AAAAAATATGCATAAGAAAAGATTGAGGGAAAGAAAGAATCACCTCCAAAATGTTAACAG GTAAGTGTGCTGGCATAACTATGGGTGCTTTTTTCTCCATTACAGTATTTTGCATATTCC AAGTTTACTTTAGTGAGTTTAGTAGACTGATATTAAAAAGTGAAGAATTACAAAGGGAAG GAAAATGCCTAACAGAATTAACGCTAACTTATTGGTAGCTGTTGATAGATTGATTAGTCC ACTGACTTAGAATGATACACAGGGAGGAGTACAGGATTCTAAATTTTATTTAGATTAGTC ATGGATACATCTCAGTGAATAATTTGTATCTCACTGATTGTCAATCACATGTATAAAAAT ATTTTTGACCTATATTAAGTTTTGTGGGACATTTGAGAATTACTAATTTTTCCCCAAAAT TGGGTTATTCTACTTGATGCTGTAGGAAAATATGGATTAAACTCAGATACAACTTTGCAC AACTATCCAGAATAACACGAAGTAGAGTGGATAAGTAATGTCACTCCTTTCTAGAGAATT ATGCTCTATAATTTGAGAATACAAGAAAGCCTAACTTCAACCCATGCTAAGGAGGTGCAT TTACTCTGTTGTGTCTAGCTTTTAAATTTGCTTTCACAGATGTTGGATTACATGGTTACT GATGATGAATCATAGGAAAAATGAACAGCTAAACAGCCTAATGTACCTTTTTATAAAAGT GAAAGGAAATTAGGTTCCACTTCTGATTGTCATTTTTATTTACATTAACTTTTTCCCTTT CAAAGGCTTGTATTCACACAAGGATTATTGAGAGCTAAGATGTGCATGAAAGAATGATCA AATACAACAGAAGTGAGTGCTGAATTTTATGGTAAGAATAAGGCAGCTTTTTAATATATG AAAATAGTGTTTCTGCATACAATCAGCAATTTTATTTGTGGTGCTTGACATTCAGTGTTA ATCCACCAACTCTAAAGCTTATTAAAAATGGCAGGAGACACATTGGCAGCATAAAGCAGA TCAGAAATTGTCGAAAACAATGAGAGGTTTATGATCAACCATAAAATTGCACTTATTTTA GAAATCTGACTTTTGCATGGAATCCACAGGTGTAGAATCAATAGCCCACAAATAATGCAG ACAATCCCAGCAGTACATTTCAAAGATCTCAAGTTGCAGGAGGGGGAAAAGAGCCTTCAT TTGTTGTTTTTCCCTTTGTTCTCTTTTTATCTTGATGTGTGACACTCGCTCCTCACCGCT ATCTCTTGGAATTAGCAATAGAATTAACAATAAAAAAATAAATGTCAGTCTTTCTTTCTA AAAGAAGGAAACACATCAAAGAGACTATGAAGAGGCTGTAGGAGATCTGCAGTCGCTTTG TCATTTCTGAAGATGTTTGCTACAAATTCCCTTAAGCAGATGTAAAGGCTATGGGAGCTA TTTCTATTGTAACTTCTATATCAAATTCATCTAGGAGCCACTCCTAAACTCTAATTCCGT AATTATCCAGGTGCCATGGGAAAATGAAAACTACTCAATGGTGTAGAAGTGGCTGAAGGT ATGGGAGGATCATCTAATTCAGCGTGGCATTTTTGGTCTGCTACTTGCTAAATGAGTAAG ATCTGAGGCCCTCTTTCATATTTCTCAGTAACAACTCTATGCTTTGTAGCATGTCTGACA GACAAGTCATTTCACTCCTGCCACCAATGATGAGCTATCCTAGTGATGCCTAAACCTTCT GCTGAAGAAATAGGAACCATGCAAGGAAAAATTAGTAAACTGAAGCTGACAGGATCTTGT AGAGAGTACCCATTAATGAACGCCGTGGAGGATTGCATGCTTACCATTCATTTTCTTTCT GCAATTTATATCCGATTTTCTACAGATTATGCAGAGGCATTATATGAATATTTGTTATAG CTACACATTTAGAGAAGCAAATAGAATTATTTAATAAATGGGTGAAAGTGAGAAAAGAGA AATAATTCAGTTCTCTTTTGCAATTCACAAAGTCACTTCCTTAGGGTGTATACTCCAACA AAGTTAAGTGCCTTTTATGCTATTTGTCTGCTGGTAGTAAGTTTATTTACATAAAAGGGC TTACAAATAAATATTAATTCCTGGTTGTTGGTGTGATTTATTACAATGTCCATAATTTCC TTTATTCCAGTTCTAAAGATTTTGCCAAGAAAAGTATAAATCTCATCATCCAAATTTCAA AAGAATTAATATATTTTTAGGCCAACAAAGATTTAGCATATTCAAATAATAACACTAAGC ACTGTATCCTTCACACATCTGTACAGGGTGTTTATAGATTTATAAAAACTTTGTAAATCA TGTGCAAAATTGTATAGCCATTTACAGCTGCATTTGGTTTTCTGAGGCATTTTGAAGGCT CATTTTTCTTTCATATGTAGTATACCTATTGATATAAAGGAATAATAGATGTATTTATTT ATAAGAAGAAGAATAGGGTGTTCTAGCTGTGGAGGCTACAGACCAAAAAATTGTGCATAG TGTATATATGGCTTTACATAAAGCATTATAATAAATTAGTTACTGTATTTTAAAATATTT CCTCCCTCTCAACCAATAAAAAAAAAGGCGATGATAAAACAGTATTTAAATAATTGGCAT AAAGTGTAACCAGTTCATCACTACTTTGTTGATTAGGTGTAACACAGAATACCGGTTACA TGGCCCTTGGTTAACTACTACATATTTTTTGGAGCGTTAGCCTTCAAAGACTTTCCACTG CTTGGCATGCATGCCGGAAATGTAGTCAAACTCATTTAAAGCATAGTGCAGTGGCATGTG CCTGTAGTCCCGACTACTCAGGAGACTGAGGCGGAAGGATTTCTCGAGCCCAGGAGTTTG AGGCCAGCCTGGGCAATGTAGTGAGACCTTGGTCTCTATAAAACAAACAAAACTCTTAAA TTTAGAGGGTTGATGGTAGGGGAAAAGGTTGAAGATGGACATTTGCAATACATTTTGAAG ACTTTGAATGTGAAGATAGGGAGTTTGACTTTTATTCTCTAGGTGGGAAAGTAATGGTTA GGAGCAGAGATTTACAGTTCACTAAACACTTTATTTGAATTCCAACTTTGCCATTAGTTG AGCTCTATGACCTGTGGCACTCTCAGTTGTAAAATGGGTACAATACTCCTTTTTTAGATT AGGATGAGGACAAGGAGGGTATATAATATAAGGTAATATAAGATAAAGATTGCATACTGT CTGGCACTTATGAAAGCTTAACAAATGACAGCTATCACTATTGGAACCACCTGGGAGAAT TTTGAGCATGCAAATACATAATCGCACCTATCATTTAGGAAGATTACTCTGACCACAGCA TGAAGGACAGAGTGAGTGAAGCCTAAAGGAAGAAAGAATAGAATTATAAAGATCATTACA ATTATCCAAGCAAATATTATTTAAAAGCCTGAAGTAGGGTACAGAAGGATAAATAAATGG CATCATAAAAGAATAGCATCAACAGGGTGGGATAACTGATATGCACATGAGGTAAAAGCA AGAGAAAAAATGATTTCAAAAATGTGAACATAAGGGTCTAGGAGGATGTTAACTCAAACT TGGAAACACAGTGAAATGATAAAATAGGGTTTGGAGTTTCCATGGGACATTCAGACTGGG ATGTCTGGCTGGACCACTGAAAATGAGGACCTGAAGTATAATGAAAAGTCTGGCTTTGGA GCCTGTATGTTTGAGAGGCATTTGCATTGAAGTACAAACGGAAGCCAAGAAATATATAAC ATGAATATTGTGAAATAGTAAGGGGAAAGAGAAAAGGTCTAAAATCGCACCACTGAGAAA TTGCAACATTTATGATGGAGCAGGAAGATAATCAAATAGAGGTGTTCTAAGAGTTGTTGA AAACATTTCAAGATAGCAAGAGAAAAGGGAGTAAGGAAAGGTGGTATAGTATGAAGCCAA ATAATTTGCAATTAAATCATCTATATCCTTAGAAACTTCAGTTTTTATTGCAAAGGATTG ACAAATGAGTGGGGGTTAAGAGGAAACAAGTATAAAATACTGCTCTGAGAAATTTGGTAG TTAATGGAAGTCAAGAAATGTTTATATTTTGAGAAGGTTTAATTTATGTATTTTGTTCAA AGGTTACATATTCAATCTCATTGGATGAAAGTTGAAGTCTTTTCAGAATCAAGGTTCAAT GATTGTCTTTGTTTCCCTTCTTTCTAGTTTCTCAGTTTCATAGATAAAGGTCAAGATAAG TTTTTTATACACACAAAGTATACACACAAGAAACCTCGCCTTAATAAAGTATGACTTTCT CTAGTCAGTTGTCTCTTCCATTGACCTCATGATTATTTCAGAATCTACATATTCCTCCTA ACTCCTCCTCCAGCTTCTCTTTATTCTTGTCAGTCTACTTCAGTGAGAAACACAGACCAT CAGAAGTGCTGATTCTTTCAACTTTCCACCATCAAATCTAAAATTCATACGTGCTCTGAA TATCCTGGTTTTTACTTCTCTCTTTTTACAACGGTCTGGGCTGATCCACTCACCTGCTAT GCTGGATTTCTCTCCTCTGTCTTCATCGGGAACCTTGTGCTATTAGTTATTACCTCATCC CCATGTATATGCAGCTTCAATTTGATGTCTTCCTGTCAGTCATCAAACAAGCTCAAATCT CAACCAAATATTTATAAAGTCCTCACTTTACTACCTCTCTCCAGCTTCTTTTATAAAGAA ATTGATGTTAATTTCAAAGCTTCATAAAGCTTGGCCAATCTTTAACAGACAGATACTTGC CTTGCCTCCTAGCTTTGCAAGTTTCTCTGCTTGGAATGTCATTCCCACCTCTCAACTGCC CTCCCCACCCCAGGGTTTTCTATACTTATGTTGTCATTCTCAACTTAAATATCACTTCAT TATAACAGTCTTTCTTCAACCCTAGCCCAGGCACTTTTCCTTATTCTAGTCCTTCTAGTC ACCTCTTGTCTTTCTTTCCTAAGAGACTGTAAATTCCACAAAGAAGAGATAACGTGTCTT GTTCATTCTTATGTGGTGTATACTGCATACAGCCTGGCATAGAGTAAGCCCTCATTAAAT TTTTGTTGAGTGTTCCCTGCAGTTTCTCATTAATACATTCCCTAGCACATTTATTATAAT GTAATTTACCTAAAGAATTGATTTACATTCAGTTGATTTTTATATTAATTGATTTTTATA CATTGAATTTTGCAGTAAACCAAGGAATATTTTCATATGAAATCATATTTTCCCACTAAG AACAATTATATTTTCAAATATGTTTCCACTGAAAGAGTATTGACCTCAACATATGAAAAA ACCATCCTTGACATTTCTGTATTTATTTCAACAAGTATTATTTCTCTGCCATATGTATTT AATTTTTCAGTTTGTGCATTTAGTTCTCCTGTACCACGAATAACTTAGTCAACCAGACAC ATAATGCATACATATTATGTGTCCTGTTGAATATTATGTGTCTGGTTGACTAAGCTATTT GTGTTATAGGAGATACCTATACCACTTAAGGGTATACATACTGAAATATCAAATAGAATT ATCTCACAATTCATTGAGTGTTTTAACTTACTCATGGCTTGAGAGCCTCAATGACCCTGC CTTCAAGCCAAGTTTATTTTAGCAGAGCAGTACATGTAGAAGAGTGAAACGAAGTACTAG AAAAAAAGAGTATGGAGATAGAAAGGTTCCTGAAGTGACAGCTGAAAGACGTGGACCCTG ACCCAAACACAGTCACTGATTAGCTGTGTGACCTTGAATAAGCCATTTTTTTTTAAATCT GCTTCATTTGCAAAATTAGTGTAAATAATTTATACCTAATTTTTAAGAGGATAAACTTGC CTTAAAAGTGTATTATATTTGTTAAGCATTGTGAGGGGTACTGGAATTCAGGCACAATCC TTATACACAAATATGTTAACTTCTTCATATGGACACAAACCAGGAAGGTCTAAAATTGAA TGAAAATATGCTGTTGTATTTGAGGTGATTAAGTAGCTAATGAACAGAAGAGACCATCCG TGCTATAACATATAAAGCAAGTAAGATTTCTTGTTAAATGGTAGGACCTCTTTCCTGTTA ATACAATAATAATAAGATTGAGGGAAAACAGCATATAATTACATGCTTGCATGTAAAACC CACTCATGTATATATATTGAATAAAAAAAGGAAAGACCAGATGGGTTACTCAATGAATTA GATTGTTTAAATATTGGTTACACATGTGGAGATATTTTAAAGTGCATATATATATATTAT ATATATATATATATATATACACACACACATACATACACACGCATATATATGCATAGATAA ATATAGTTGACTCTTGAACAACACACATTTAAACTGTGTGGGTCTACTTATACACAGATT TTTTTCTACCTCTGCCACCTCTGAGACAGCAAGACCAACCCATCCTTTGCCTCCCCCTCC TCAGCCTACTCAGTGTGAAGACGACAAGGATGAAGACCTTTATGATGATCCATGTCTGCT TAATGAATAGTAAATATGTGTTCTCTTCTTTATGATTTTCTTAACATTTTCTTTTCTCTG GCTTACTTTATTGTAAGAATATAGTATATAATACATATAACATAGAAAATATGTGTAACC AATTCTTTATTTTATCAGTAAGTCTTTTGGTCAACAATAGGCTATTACTAGTTTAGTTTT GGGGAAGTCAAAAGTTAGGTGTGAGGTTCTGACTGTGCCAGGGGCTAGCACCCCTAACCC ATGTGTCGTTCAAGGATCAACTGTACATGTACATATGTATATGTAAATATATGCCTAGAC AAATATGTATGTGTGTACGTGTGTGTGTTTTTCATAAATGTATAAGGTTAGCATTTCACA TAAAAGGAAAAATAAATAATTCAAAAAATATTGCTGATTTATCAACTGCTTGAAATATAG TAGAAATGTAGAAATTTTATATTATACCCTACCTCAAAATATGTTTCAAATGAATAAAAG ATTAAATGATGCATTATATAAACTTAAAAGAAAATACAAGTGAATAGTTATATTTAGTTG GATGTGAATACATTTTCTAAATTCTATCTAAAACCAAAGCTAGGATCCAGAAAGGAAAAC AGTTTTTAGACATGACCTTATTAAAATTTAAACTCTGTTACATCAAAAACATTCATAAGA AATATTCAAATGACAAACTAGAGACATTTTGCAATGTATATGACAGAGTTAATAATCTTA ATAAAAGAACTCTTTCAAATTAACAATTATTAAGACAGAGACTTGTAACCAGAAGATTTT TTTTTTTAAGTAAAGGCAAAGGGCTTAAATAAGAAATTTACAAAGAGAAGCGAGGAAGGC AATGGGTTGATAAACATAAAAAAACTGTTCCACTACATTAGTTCTTAAAATGCAGATAAA AACAAGATGCTTCCTGTTGATAAGGGTGTGAAGAAATGGTCACTCACATTCCCTGCTAGT GGGAATATAAGTGTGACCTTTCTAGCAGACAGTTTAGAAATACCAGTGTTGCCAGTGGCA AATCTGTGTGGGTCTGCGGCAACCTCAATTCTCGCGTCCTCAGATGAAAATTCGACTGAG GGGCATAAGGCAGGCAGAAGGAGTGATGGAGGCAAGTTTTAGATCAGGAGTGAACATTTA TTAAAAAGCTTTAGAGCAGGAAATGTTACAGTAGGTAGCTCGTCAGACATGAGCACAACA GGAGAGGGTTTCCCCCGCCCTATCCCACACACCAGCAGTGTCAGGCGATCCTCACGTGAT GGTCAGGCAGTTGTTAAGCGGTCTCTCTGAAATAATAATTGGTCACTGCCAGCACCAGGA AAAGGCAGTCTCCCCCAAAATAGAAGCATCTGAAGCTGGTGATCAACACTTTCCCAATAA GATCTCGGGAGATGGGCAGATGGGCTCACACATGCTCACTAAGAGGCAAAATGGCGGAGT TTAAATGGTATATGACCTCCTAGGGTCATTAAGTTGGTAAGGGAAGAATGCCTCTGTAAA CACACTGCACATGCTCACCTCTCAAGTGCTAGCAGGCCACTGTGCATACGGACAGCCCAC CCCAGGGAAGAATCAAGGGAAATGGGATGCAAGACCCTGCAAGTATGCCTACATATAGAA CCCCAAGTCAAAAGGTCAAACTGTGCACTTGTCTTTCAAGTTACCCCCGTGGCCTACTTC CAAGTGTAATTTCCTTCCTTTTGTTCGTGCTCTAAAACTTTTTAATAAACTTCCACTCCT GCTCTAAAACTTGCCTTCATCTCTCCTTCCGCCTTATGCCCTTCAGATGAATTCTTTCTT CTAAGGAAGCAAGAATTGAGGTTGCTGCAAACTCATACAGATTCACTGCTGATAACACTA TAAGTATTAACAGCTTTTAAAATGTGTGTACCCATTGATCCAACAATTTTATCTTTAGGA ATTTAAGAAATGATCAAAAATGTAACCAAAAATAAGTGTACAAATATGATCACTTAGGGG TTATTTACAATAAGGAAAAATGAGAAATGGCTACCTAAGCATTTTGGCCAAGGTAGATTT AAAAAGTATGAAGAAATTTTTATAATCTTTTGTTAAAAGCAACTCTGTAGCATTCATCAA GAATGATATTTCTTAAATATTTATACCCTTTGACATATTGATTCATATTCTAGGAATTTT TCCTAAGGAAGCAATTGGAAAAACAGATAAGCTAAATTCATGAAGGCACCCATTGCAACA TTATAGCAGTCTATCATCCATTGGATTATGAGCATTGGGTAAACCAATAATACAGCCTTA AAATTGGAAAGTATGTGCCTATTAAAAATGTTGTTTATACAATGTTCCCAATGTCTTGGA AATTTACATATGTGGAACATTAGAGTAAGAAAAGAGACTGTTCCTGGGTCCAAACCAGCA CTCTGTCACCATCTATTCTGCCTTCTCTAAGCTCTAATTTCTTAATATATAAAGTGGGGG TATAATTGTTCAATGCTTATAGGGATTTTGTGATGTTGTAAGGATTAAATGAGATAATGA ACATAAAGTACTTACCAGAGGCACAGAGCACTCAATAAAAATTAACTATTTTTTAATGAC CATATAAGAGTCTATAAAAGGATGGCTATAACTGAATATAGAGTGAAATAATTTACTGCA GCATTAAAAGTGGTTATCTTGGAATGGTGCACTTATAAGTGATTTTTTTTCTTGTGTATA TTTTCCAGATTTCTTTACTTTCATGATTTTTTAAGTATATTGGTTTTGTTTTTTATTTTG TTTCCAAGTGGAAGATAGATAAAGGATTCTGAAAAGAAAGAGTAAATCAGACAGGCAGCA GCAGTAGCCAGGAGCTGGACAACCAGGGCAGAGCCTCTGTCAGCCAGCACCATCTGCCAC ATAGCAAGTAGGCAGCATCCTGGACGAGGAGGTGTCTCCTAGTTGGCAGAGCAGTGGTTC TTCAGTCGTGGTGTGTATCCAACCAACAATGGAGCCTGAGAACAACAGGGATGCCAGGGG CCCAAGTCCAGAGCTTTTAATTTGATAAGACTGAGGTGAGATATAAGTGCTTGAATTTTT AATAAAGACTCCACCTGTGATTCTAACTCATACCAAAATTTGAGAATCCCTAGGCTACAG CATGGTATGAATAAGGCCAAAGTTCCATGTTGCACCCCCGAGGGAGTCCCATAGTTAGCC GCTTTGTGTGCCTGCAGGCTGCATGCCTGTTCATTGCCATATGTCTAACCAAGCCTGGGC CAGTTCAGAGCATGAATAGAAAGGAGCAAATTACCTCCTTCCTTTTTTCCTTTCCACTTC CCTGCCCCTCCACTACTAAACCTATAATCCGAAACATATATCCTGTTATTAGTGAATCGG TAATAGCACCTTCACTAGACAGTAAGGGGGTATATTTTTAAAAGAAATAGACCTAGACAG CTAAATATGGTAGTTGATGAAGATCAGACAAATCAGGCAATCTAAAAAAGTGGTCAATTT GGTGAGATTCATGTTTAAGAGGGCAGAGTAGCTTTGCTTTACAGAGATTAGTGAGAGTTT GTAGTTCTTTAGTGTTCATCTGGAATCCCCTAGCATTTTCCTCATACTTTTGCTGCTATC ATCTATCTGCCATCTTGTGACATTACATTAAAATATAATGAGTTCTAGGCCTGAGTTCAT CTGAAGTTCAGGGTGTTGCAACATATAAAATGAGCTGACGCCATGGGAGTCAGAAGTGTT TTCATCCAATACAATATCAACCTAAATGCACTCAGTAAGTGAAATCTGCAACACTCAGAC ATCTGATTTTTACTTGCCCTTTTGCAAATTCCATTTATGTTTGCTTTTGAAAATAACTTT CAATTAAAATCATCCCATGGATTTTACACTGTGTTCAGTTTCTGATATCAGAAGGTGGTT GTGTAATTACATTAGGGTTGGTTGGGATGTGCAGAAGAATCACTTGTGCTCTTGCCTTTT TAAAGTGGAGCCCAGTGGAGCAAATTATATCACTTGAATATTCCTGTAGGTCTCACCCAA CTTTGCTTCTTTTCTTGTGGTTCCCTTTAGATGTGATTGTTTTAAGCGTCATTACCTATA CCTTTTTGCTCATTCATTGTGGATATATCCATTTTCACTTTGCTTCATATTAACAAATCC TCTTGCTTCTATGGTGGATTAAATAAGCCAGCTTCTTTCAAGGGTTGGAAACATCAAATA ACCTTGCTGTTTGTCACTAGTTTCCCTGTGCCATAATGAAGCTGCATTTCATGGCTTATG CAATTGACACCCAAAGAGAACAATGGGTTTGTAGTGTAAGCATGAAGAAAACAGTTCCTA ATATCTGCTGGACTTAGGTCCGGTCCCCTCTTCTTTGAATTCGAGTTATGGCAACCTGTT TTTTCATTTTTAAAATGAAGATGATAGTATGAATTTTGCAGGATTATTTATACATTAATA ACAATGTACATAGAGAACCAGGGATATAGTAGGCATTTAATAAATTGTAGCTATTGTTAT GAATGCATAGAAAGTATATATATATATACACATACATATATATAAATTATGCAAAGCAGA AAAAACTAGCTAAAGTAAATGATGACAGAATCAAGAATCAAAACTGTGTTTCAAGTAGTA TTACACTTAACAAAAGCAGGCTGCTAACTGCCTAATTCAGTGGGTATTTTAATATCTTTG TGCACTATAATTTACTGCCATATTTGTCCCTGTTGACCACTTTCAGTCTCTTGTAACTTC ATATGCCCTTGACCCATTCTTTCCTTATTTTCTTCTAACCTCTTTGGCTCATCCGTCTTT GTCTCTTTTAAATAAGTGGTTTCTGCCTCAGTTGATCCTCTTAATGATGGTATTACTCAG GTTTCATCCTCAACCTTCTGATCTTTCCATTTCATGTAGCCTTTCACGGATTTGACTAAT GATTCACTGGTAAACATCAGACTCACATTTACTGACTGTTACCTATCAATCCTGCACCAA TATTCCAAAAGGGAACTTACTGAATTTTCATATGCCTTCAATTAATTCTCCACCTGGATG AATGATATCAGTATTTACACAGATACACAAACCAGAAATCTAGACTTTTCAGTGGAAGGA ATCATAGGTCAACATCTTACTCAGGACCTAGAGGACAAGTTTTAAGAATAGCTGCTTCAA CATATGGAACATAACAACCAAGTACAATGTATGCACATTGCATGAAACCTGATTCGACAA TCTAACTGGAAAAAGACAGTTTTTAATCACTAAGAGAAATTTAAATAGGATTATGCATTG TGGAATATTGGGGATTATTTTTGATTTTAATTAGATGTGATAATATCATTCCAGTTATAT ATACATATAATATAAATATATACTACACATAATTATAAATATATGAAATCGATGTTATTT ATATGAATATATATTATTTCTATGAATATATGAAATATATATTATTTACATTTATATATA ACATATATTTATACATTATATATACTAATATACTATTACATATTAATATAATTCCAGTTA TATATAATATTCCAATTATATATGTATCATTCCAGTTATATATGTTATGTAATATAAAAT ATATATTAGACATCTATTATATATACATATAACTAAAAGATAATAACTAAGGATGATTAT AAAAAGATAATCAGAGTACTTACCCTACAGGTTCCTTTTAAGACTTTACATGTCTTACTT ATTTCAGTTTATTTCAGTACTTACACTGTGTTCAGTTTTTGTTATCAGAAGGTGATTGTG TAATTACATTAGGGTTGGTTGGGATGCTCAGAAGAATCATTTTGCTGTTGCCTTTTTAAA GTGGAGCCCAGTGGAGCAAGTACTATCTGGTAAGTACTCTGGTTATCTTTACAGATGAGG ACACACACACACACACACACACACACACAAACACACACATATATATATATAACATCATAT ATATATATAACATCATATATATAACATCATATAACATCATATATATATAACATCATATAT ATATACCATCATATATATATATATATATATATATATATATGCGCACACACACACACACAC AGCAGTTAAGGATGCATGTTGTAAATTGAAGATTGAAGAACCTGATGTATTCTAGCAACA AATAAATTGAAAAGATAAAGAAAAAACAGAGGCAGTGGTGATAGAAGACACAAAATGAGC AAAATAGTGGTAACTGTGAAAGTTGGGTCATAGGTGCATAGTAATTCACTATATGATTCT ACTTTTAGGTATGTTTGAAAATTTTCTATTAGACATCTAACAAATGATATTTATGGGCAC CCCACTCCAGTATCAAGATCACCAGGAGTGGATCCCTGGAATCTGCATTCTTAAACAGTT CCCCAGGTGATTCTTATGTGCTCTATGATTTAAGAACCACTGTTGAGATTTAAGATGTCA GGATCATTTCTGTAATAAATTTGTCTCTCCCCAAACAACAATTGCTGCTGTTGGAGATGT CCAAGAAAAATCTTAACTTCAGGGATGAAAATATCAACACATCAATCTCAAAGATGAAAA ACACTAGCAGGAATTCTGCCACACAGCAGAGCCCAGTTACATTGTGGGGACATAAATCTG ATCTATTTCATGAAATAGAAGTCACGTTTTTAGAAATTACCTACTTTTTATTCCTAATGC AATAAAAGATGACATTGTCTCTATTGAGCAAAAGCAGACCTGGATAAGAAGAGCATGCTA CATAATGAAAATGACAATAACTGAAATAAAAGTCTCATTTGAAAGTAGTAAAAAGCAGAC CTGACATTGCAGATAATCAAATCAGCCATACCCAGAATACTGAGAAAATGAAATCATGGA TTTTAAAAATGACTCAAAATATAATTGGCATAGAACTCAGTCATGAAGATAAAACCTATA GACTCAACAAATGGATCAAAATTAATCATTAAAGTTATAACAAAATGTATTTCTGAATTC TGGGGATAAAAAGACCCCAAAATATTTGAGTTTATTATATCTCAAGTAATGCTAGTAGTC AGGGTAATGACACCAACTGTATCTTGTTATAATTTTTAAATTATTGGAGATAGTGATGAT GAATTCCATGTCTCAGAGCAGGAAAGTCACTTTACTTCGACAGGAGTAAAAGTTACCTTT TTTCGAAGTTCTCATCTGCACTATCATAGACCTTAAGACAACGAAGCAACTCTAGTATTT CTGGGGTGAGGACAAGGAAATACTGAGTTGTTATTCATATAAAAAGAAATCATATGATAG GTAACATAGCAGAGAATATGCCATCCAAGAAGCTGTTTTGCCAAAGTTATTCACACATAC AGTTAAAGTCACTGAAGGAGAAATCAAGAAAAGGGTCTTACATCTTTTGACTCTTATTTT ATGATAATATTCTATTGCATCAATCCTAAATTTAACTTTTCCTCCCGCTTATTTTGTCAT CACTGAAGTCAGGATGCAATCAATAGTGTCCTACAGTTGAACTTTGACAGGTGGCAGTTG TGACATAGTTGTCATTGCCTGCACATGCACACATCTGGCTGCAGCTCCTGTTGATGTGAC TGAACAAGGGCAACCCCTTGATGCCTCAAATGAACCATTTCAGCATGATTGGAGAAAGGA ATATGAATTGTGATTCTTGCCTGAAAACCTTCTACTGGCATCCTCTAGGAAGATCAAGAA AATATAAGCACCAAACTTACAAAATGGTGTTAGCAGCTTGGGAGAAAAACCCTGCAGATG GTAAAAAGCACTTTGTGAAGAATGTTGCTTTGGACTATGGGTACATATGGGTAGTGTTGC CTTGGGTTATGGGTACATTATGCTATTCTCTCTGTTATTCTTGGAAAGTTTTTGAAATTA AAAGTCTTTTTAAAAATCAGAAGAAGAAGAAAGCAGGGAGAAAGCAAAAGGAGATAATGC ATTCCTAATGCTCCTGATTGTCCAGATGATATTGAATAGAAAAGCACTGAGATGGACATG TGGACAACTCAAAGTTGCAAAGAGATACAGCAAAGTCAGTCTAACCAACTAAATATATAT GTTTCTTTTAATATATGAACAAGAGTGGTGTCTGATGCAAATCTGTACTTAGGTCATGTA CTTAGGTCTGTACTTAAAAATCAAGTATAAAATAAAAATTGTAATAACAAAGCATTATGT CATAGTTTAATTTGAAGCGTTTTTTTTCTTCCTTCGTAGCACATACAGTGGTACTTCTCA AAATCAATGGTGTAGTGGATTTTATGAACTATAGAAATAACTATTATTTTTTAGGCACTT GCTATCTGGTCACAGTTTTAAGGACTTTACGTATCTTATTTATTTCTTAAATGGACCCTG TAGGGTAAGTACTCTGACTATCTTTACAGATGAGGAGATTGAAACACGAGAAGCTTAAGT AATGTGTCCAGTATCTCACAGCTAGTAAGCAGCAGAGCCAACATTCAAATCCAGACAGTC TGACACCAGTGTCCAAGCCTGTCACTACTATATCAGTGCCTCAGAATGACTCTAGACTGG GGGCATCATTGTGATCGCTTTATGAATGTACAGATAAGCAACTAAGGCCAGGAGAAGTTA AGCAGCCTGACAAGAAGTGTGCGGTATAGTGGATAGACTGTAATCTAATCTTGTTCTATG TATACACACATACACACACACACACAGACACACACACTTCCCATTATTGCCACCATTGGA AGCAAAATTGAAGAAAACAGATACAGTACATTTTAAAAGAGAGATTGTTGGCTGTTGGTT TATGTTATTTAATCATAACAACAGTGCTTCATGGCCGTTGCCATTTTCCTTTGTGTAACA GCTGTAGAAATGAATTCTATAGAGCACAAGAAACTTGTGGCCATTTCCAGAACTCTTCTA TAGCAAAACAAGAATGCGGACCGAGGCATATTTGCCCCTAAAGCCCCATCATCTTTGATT TTTCAAAAATAATTAAACGCACGTACTGACGCTGAAAGGAAGAGTGTTGCTAAGCAGAGG TTGCACACTGGCAGCTTGCAGTTTGAATTTTGCCTATAGATGTGGTTGGCTCGTCACATG CCACGTTTTCTTTAAAAATCATGTTAATTTTTAAATACTGAGAGGTCACCTAAAATCTGG ATTTTTGCAGCTTCTCTTGAAAAATGAGAGAATTTGGCAATATTACATCTGAATCCCTGC ATGACAGTAACAGCTGGAGCTGAGTAGCCATTGCTTCCCTAATCTAGTTCCCCAGTTCAC CTCTGCGCCAACACTCAATTATTCTTTTACACAGGTTGACTCTGCCTGCCTGGCTTTTAG TTGGTGACCTCACATCTAAATGGCTATTATAATTAAGACAGCTATTTACTTCAAAACAAT ACGCTTTGACAGTTGCAAGCAAGTATAAAAATTTGTAAGTTAGAAGGAGCAGTGAGATCT GTTTTGTGATATCCAGAATTATATGTGGTAGTCCTTTCACAGAGAATTCAGTTCAAGCAA GTGATTCATCTCTTCTTTTTTAAAGTTGATTGTAGTATTTATGTCTCCAGAATTTTAAAA AATTTACATTTTACTTTCACATTTTAAGATCCTGAATACAGAGTTAATGTTAACATTTTA AGACTTAGTAACTAATTACAATTGGATACTTAAATGTTAATAATATTCACGAGAATCCAG ATTATATGTTTAAAATGTATGTCAGCAAACTTATTTCGAGAGAATTTTAAGGGCTGTGGA GAAAAGAGATTTATAAATTCAAATAATTGCAGTGTCTGAATAGATTCTTTCCTTTTTTCT TTTTTTCTACCTAAAAGCTTATGACTTTTTGACATCAGTACTTTATTTTACTTAAAAAAT TCTATATCTGACCCTAAGTAGTTATCAATATTAGAAAAAAAAGTAATGCTGATTTCTATA CAAAAGACTTATCTATGAACAAATGATTAGTATATTGCTTTAAAAAATTTAATAACAATA ACAATCCTATGTAATGTTTAGATTTATTTTGATTATTAATTTGAAGGGGCATACATTTAC ATTATCTTTAAAAGACTTCATATGCTATTGTTCAAGTTGATACTGGTACTTACCACTAAC AGTTCACAGTGGCTAAGAGTGGTACTATAGGAGGCTAAAATTATTCCTGGACAAACACAG AAAGAAACACAAACAGAGGAGGAATGTGGAACAGCCTCCAAGATAGACTAAAGTTACACT GTGATAGGGAATATCCACCTAAAACATGATCTCCTCCTCCTCCTGGCTGACTTCAAACCC ATCTAATGTGTACTTCATCAGTAGAATGTAGGGAACATGCACCCTCAATATGTTTACATT TATTTATATAAAAATTCAATAAATTTTCCACTGCAGTAATGTATGTCATACATTATAAAG CATATCCTAATAAGAAATTTTAAAGGATGAGATAACAAAAGTAGAAATAGATGTTCCAGT TTTTTCCTCAACTCCCATAATGGACTACTTTGTTCCTTCTTCTTCATTGTGATCATCCCA GTTCTTTTCCAAATTCTATTCTACGCAACACAAGTTCAACGTCATTTTAATAAGAATTCC ATGAGAAAGAGTTTCATTTTCAAGTAAGTTTGGGAAATATTAGGTTAAAATTAGATAGGT TTTCTTGTTGTGTGACTTCTCATCTTTAATACAGAATCCTGTTGTGAATCTTTATGAGGG AGAGCGTCTATATGGCTAATACTCCTCCAAGATCTCTGGGAAATCCTGCTGTGTTCAAGT TTTCTGAAAATCATCTTTGCTTGCTGTTTGCCAGCTCTTTCCATAGGGTCTCCACTTAAT CCCAGGAAGATCCTGGTAAACATTTCCAACCTCTTTATATTACAAACCTTTCATCTCACT AAACTTTCCCTTATTTCCTAGGACCAACGTCCACCCCTTTGTACTCAGAACCTAAGATCT TTTTGGATAAGCCCTACTCAGGTCTTAGCTTTTGCCCTTCTCTTGTCCATGTACGTGGAG TACCATGGCCTTTCACAAAACTTGCTAGCATAGCTTCACTACAGTTTCTAGGATGAATCC TGGCTTTGGGTCAAAGAGAATTAAGATAGGTCTGCCCCATAATTTGGGACTCATCACAAA TTCACTCTTCCTGCTTGATCTTGATCATGTACAGGAACACTTATTCTGATAACCTTCTAG TTCATAGGACCCAGTCCCCACTTTGTTCTCCATTGATAACCAGGTTACCGCTCACCTGCT TGGCACCTGTCCATTTCAAGAAAAATATTATTATTATTATAAATACTATCATTGTTTTAG ACAAAAGCAAAACTTGGGCCTGTTTTACAATTCAATAAAATCAAACATTTGTGTTTGATT TGAGGGTCAAAGATGTACATTTTTTTTCAGCTTTAGTATTTTTTTAAAGTATTGCTCAGT AGTGAGTCTTAATATATGTCAGAATAGTACAGTTGAAAAATAATATTGACCCACTTTAGT ATTATGAATGTGAATCCTCATAATTATCTTCTTTTGTTTTTGTTTTCTACCTTTTTTATG ACATCAACATACCAGAATGAACAGAGGCAGTCTTTCTTGGAGAAATATTTCTTTTTAGAG GCAAGACCACAGATGACTTACAGACATATCCCTTACTTTTCTAAGCTAGCTTGGTATTTT GTTTTGTTTTATATTTCTTTTGCTACAATAGTAAAATATGGTTTGGCCATCAGATGCTAA TAAATTATGGCACTTAAAATGTGGCAACATTTGTTTTAAAGCTTAGGCTATTCGCCACTC AATACGTAGTGTAAATATTTCCCCCTACCTTCCTACCCTGTAGGTTCATGAGCCATCAAA TACTGTAGTAAAACAATACTGATCCTGCAGCAAGATATAAAAGAAGGCTAGCAATAAGGA CAATGTGATTTTATACTTTAATATCTAAGATTAGATCCTAAGTCCAATATAAAATAATCT CATATTTAAAATTCAATATCTTCTGACTTCCCAGTTCTGAAATCACTTGAGTAGACCAGT GCAATGCATTCAGGACAAGCAGGTTTTTTGCTGATATGGTCCTGAACTAATACTGAGGAA AATTTGAAATTGCCTAAAATCAATCCTTATATTGGTCTCTGTTAGTGAGAGTTAACCACA GCAGATTAATGAGATTAGAAAGTGAGGAATAAAAGAGACATTTATCCAATAATCTTAGCC ATAGAGCATACTGACTACTAACTAAAAAGATTTATCCGACAAGTAAGAGTTTTTTTTTAA TAGGAATCTATCCTGTGTTTCAAAAATTACAATGCAGATGCTAACACCTTAGTTCTACAC TTAGCCCTTGTTTCATGAATAGATTTATCTTTTCCTTTTTCACTACATTTCTTTGCACTC TGTCATCAAACATTGATAAGTCTTAAAAGTACATTACTAGATTCTCTTCTCCACTTAAAC TACTATCCCATTTTCCCTGCCTTCATTTTAACACTTCTCTAATGAGTGTTTCTTTTTTTG TTTGTCCTGTGTTTGTTTTGAGATGGAGTCTTGCTCTGTCGCCAAGGTGTAATGCAGTGG AACGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCCCCTGCCTCAGT CTCCGGAGTAGCTGGGACTACAGGCGCACGCCACCACACCTGGCTAATTTTTTGTATGAT AGTACAAACGGGGTTTCACCATGTTGGTCAGGATGGTCTTGATCTCCTGACCTCATAATC CGCCCGCCTTGGCCTCCAGAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGCCTCT AATGAGTGTTTTGAACCCCTGCCTCTTTTCAGAAAAAAAAAAAAATAGTAATTGCAGAAT TCTCTAGTAAAATGACTTCTGCCTCAACAGCCTATTACAACAAGTATTTCCAAGGTCACT GACAACCACTTTCAAGACAAATCAAAAGATTTTTCTTACTCCTTATCTTCTTTAGAGTAT CTGGCACTATTGATCACATACTTTTTTTTTTTCTTTTTCTTTCTGGCATTTTAAAATAAT TTTTTTCTTTATTCTCTAGGATATGAATTGCCTTTTCATTTTTTGGAGGTCAGATTAAAT TTTTATTTCTCTTCTAGTACACACATTCAACTATCTAGAGTGGCCCAAATTATATATAGT AACTCAAATTTGAGTTGTAAGCTGCCAATAAAATCAGTTGTAACTGAATTTGGTGTTTTC ACATTTATGGCCAAATACATGAATTCTTCCTTTCTATAGAAGAGCTCATCAACCTCCTAC ATGGTAGATTCAGGAGAGGCACTTCCAGAAAAAGTAACTCCATTTTCTACCCCTTCTAAA TTCTATAAAAAACATATTACTACTGGGATTGAGAAATCTCCAATTATTTTTCTGGACACA CATAAATGATCCTTGTTGCAGTTTGATTCTTGGACATCCAGTTGATATTAATTTTCATGT AATTTATGACGAATTGTTTTGTCCTAGGGCTAATCTCTCTCTGTCCTTCCCAACCATGAA AAACACAAGGCTCAGAATGTTCTTTTTTTTTTTTTTAAATTATACTTTAAGTTCTGGGAT ACATACATGTGCAGAACATGCAGATTTGTTACATAGGTATACACATGCCATGGTCGTTTG CTGCACTCATCAACTCATCATCTACATTAGGTATTTCTTCTAATGCTATCCCTCCCCTAG CCCTGCCACCCCCTGACAGGCCCTGGTGTATGATATTCCCCTCCCTGTGTCCATGTGTTC TCATTGTTCAGCTCCCACTTATGAGTGAGAACATGTGGTGTTTGCTTTTCTGTTCCTGTG TTAGTTTGCTGAGAATGATGGTTTCCAGCTTTATCCATGTCCCTGCAAAAGACATGAATT TATCTTTTTTTATGGCTGCATAGTATTCCATGGTGTGTATGTGCCATATTTTCTTTATCC AGTCTATCATTGATGGGCATTTGGGTTGGTTCCACATCTGTGCTATTGTGAACAGTGCTG CAATAAACATCCATGTGCATGTGTCTTTATAGTAGAATGATTTATAATCCTTTGGGTATA TACCCAGTAATGGGATGGCTGGGTCAAATGGTATTTCTGGTTCTAGGTCCTTGAGGAATC GCCACACTGTCTTCCACAATGGTTGAACTAATTTACACTCCCACCAACAGTGTAATAGCC TTCCTATTTCTCCACATCCTCTCCAGCATCTGTTGTTTCCTGACTTCTTAATGATTGCCA TTCTAACTGGCCTGAGATGTTATCTAATTGGGGTTTTCATTTGCATTTCTCTAATGACCA GTGATGATTAGCTTTTTTTTCATATGTTTGTTGGCCGCATAAATGTCTTCTTTTGAGAAG TGTCTGTTTATATACTTCACCCACTTTTTGATGGGGTTATTTTTTTTTCTTGTAAATTTG TTTAAGTTCTTTGTAAATTCTAGATATTAGCTCTTTAATAGATGGATAGATAGATAGCAA ATATTTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGATAGTTTCTTTTGCTGTGC AGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCTATTTTGGCTTTTGTTGCCATTGCTT TTGGTGTTTAGGTCATGAAGTCTTTGCCCATGCCTATATCCAGAACTTTTTATTGTTCTG TTTTTCATCTTAGGCTTTGTTTTCATCAGCTGATTATTTTTCATGCCTCCTGTACCTATG TTGTTATTTAATATTTTATTAATTAATTTACTTAACTATTTATTTTGTGAGCAAGCTTAT CCCCTTTCCTGGACTACTGCTGGAAACAAACATTCAAGCACTCATTGGTGCTAAAGGCAA AGGCCTCTTCAGTCTAGGCTGTGAGAAGTAGAAAGCACCACTATGATATTTCATTTGCCT AATTATTGTTTCTTTAATCACATCAGATTGATTACTTAAACTACTACTATCCTATAGAAA TATAATGTGTCTATATAAGTAATTTTAAATTTAACAAAGGTAAAATGAAACAGGTAAAAT AATTTTAATATGTTTTATTTAACCTAATATATTTAAAATATTATCATTTCAATATGCATC AGTATAAAGTTACTAGCGAGGTATTCTTACATTGTTTTCTTTTTGTACTAAGTCTTCAAA ATCCAATGTGTAATTTATACTTACATCACATCTCATTTGGACTAGCTACATTTCAAGTGT TCAGTACCTTCATGTGGCTCATGGCTCCCATATGGGACAACACAGGGCTGAACTGTTAAC ATGACAAAAGAGTGGAAGTGGAGGCCAGGCGTGGCAGCTCATGCCTGTAATCCCAGCACT TTGGGAGGCCAAGGCAGGCAGATCACCTGAGGTCAGGAGTTCAAAACTAGCCTGGCCAAG ATGGTGAAACCCTGCCTCTACTAAAAATAGAAAAATTAGCTGGGCATGGTGGCACGTGCC TGTAATCCCAGCTACTCAGGAGGCTGAGGCCGGAGAATCGCTTGAACCTGGGAGGTGGAG GTTGCAGTGAGCCGAGATCACGCCCTTGCGCTCCAGCCTGGGAGACAGAACAAGACTCCA TCGCAAAAAAAAAAAAAAGTGAAAGTGTAAATGGAAAAAAATAAATCTATATTGCCAATT ATATTTCAATTTCTATAAGTGACTTGGTTGTTTTCTAATGAATTAGCTACTTTAATCTAT CTGGGAGTGAGACATAGTCTTCATTGTATACCTGGCCAACAGGGGCTCCGAAAGGTAGAT CATTTCTCAAACTTGATTCAGCTCATAAAGTCAAAAGTGTGGATTCAGTCTTGTGTTTGG TCTTTTCTCACCTGAATTTTAATTACTCTGAATTCTGTGTTAGCTGGCAAGGCTGGGAGA ATTGTGTTCTTTCTAATTTGTCCGTAGCTGCTACAACAGGTTTGATACTAAGAGATAGGT ATGATAGTACAATCAGAGCCATTTGGGGGATGTTTTTATTTTGTCCACAAGAATAACTTG GGACCTTTTACAGTTACACCATAAATAGTAAAATTGCATTTTGCATTTAGATCTGTAAGA GAATGGCTTATTCTGTGTATTCTATGAAGAGATTAATTTTCATGCCTCCATTTTATTAAC TGAGTGCTGACCTATTAGGTGACACACTGGACCCTACAAAGGAGGCTTTTATAAGATGGC AAGCTGGGAAGATCATACATAAGAATAGCAATGATAGTGATGATGATGATGATGCTAGTA ATTTCTGACTTGTATTGAGACCTTACTATGTTCTAGGCACCATGTCAAGCTCTTTTTAAA TATTAGTTCATTTAGTCCTCACAAAAACACTATGAAATGTGTAAAATTATTATTCATCTT GCATAGATGAGAAACTGAGACACAAAGAATTCACAGAGGGCTGGGATGCCAACTCTGAGA AAAGACAGTTTTGTGATCTTATTCATTATAGGAAAGACATATTTCCCAATAGAAAAATTA TTTGTTCCAGTTGTCCAGACTTGAAAATGATGACTCCATCTTTGTCCAGTGCTAATGCTC CCATTCATCACTAGTTTCCATCTAACAAGGCTTATTTTTAACTTATTTCTAACTTCCTCC TATTTTTACTGGTTTCTCTCTGTCTTCTAACACTTAGCCCTGTTCTCACTTCTACGTAAG CTGTTTTCCACTTGGCATTTGTCCTTGGCCTTCTAATCTCTAGTAACTACGTTGGGGAGG GTAACATACATTGTTCCTTCCTTGGGTTGAAATTCCCAGCTTTAGCCTCTTGTCAAAAAT ATTGTTGGGCCCACTTAGGTCCTTCAGAATATTCACAGCTCATGTCTTTGCCCACTTTTA ATAGTGTTTTTTTTTTTCTTGTAAATTCATCTAAGTTCCTTATAGATGCTGTATTAACCT TTGTCAGATGCATAGTTTGCAAATATTCTCTCCCATTCTGTATCAACTCTACTGATAGCT TCTTTGCTGTGCAGAAGCTCTTAAGTTTAATTAGATCCTGTTTGTCAATTTTTGCTTTTG TCGAGATTGTTTTTGGCATATTCATCATGAAATCTTTGCCTGTTCCTATGTCCAGAATGT TATTGCCTAGGTTGCTTCCAGGGTTTTTATAGTTTTGGGTTTTACATTTAAGTCTTTAAT CCATCTTGAGTTGATTTTTGTGTATGGTGTAAGGAAGGGGTCCAGTTTCAATCTTCTGCA TATGGCTAGCCAGTTATGCCAGCACAGTTTATTCAATAGGGAGTCCTTTCCCCATTGCTT GTTTTTGTCAGCTGTGGCAAAGATCAGATGGTTGTAGGTGTGTGGCCTTATTTCTGGGCT CTCTATTCTGTTCCATTGGTCTCTGTGTCTTTTTCTGCACCAGTGCCATACTGTTTTGGT TACTGTAGCCCTGTAGTATAGTGTGAAGTCAAGTAGTGTGATGCCTCCAGATTCGTTATT TTTGCTTAGGTTTGCTTTGGCTATTTAGGCTGTTCTTTTGGTTCCAAATGAATTTTAGAA TGTTTTTTCTAATTCTGTGAAATAATGTCACTGGTAGTTTGATAGAAATAGCACTGCATC TGTAAATAGTCTTGGGCAATATGGCCATTTTAATAATATTGAATCTTCCTATTCATAAGT ATGAATGTTTTTCCACTTCTTTGATCAATTTGTAATTCTCATTGTTGAGATCCTTCACCT CTCTGGTTAGCTGTATTTCTAGGCATTTTATTCTTTTCTTTTTGTGGAAATTGTGCATGG GATTGCGTACCTGATTGGGCTCTTTGCTTGACTGTTGTTGGCTTATCACCATCATTTTCA CCGTCTTCCAGACATTACACGTTGATGTATTATTGGTTCTTTCTTTTCCTTTGTTCTCTA CTTCCAGTCAAACTCTTGCTGAATCTTCCATCATCTTGCTCTTCATCAGTCCCTTGTTCT CACAACTAGATAATTAAAGCTAAATTCCTAACGGGCTTTCCTACCTCCAATCTATCCTCC TTTCATTTTATACTGCACTGCATTTATCCACTATTTCTTAGGATGTCTCAGCCTGTGTCT TAGGCTTCAGTGGAAATAGAGTCACCAACTCTAGGCCAGTTCTGGACCCTTTCTGGCTCA CAATAGGGTCTCTTGATTTATAAACTCATGTTTGAGAATTAGGCAATATCTCTGTAAATA AAGAGAGAAGTCAAAGATAATGCTTCATCTTTGCTAGATATTCCAAAAGTGACTCATGCA GCAGATACAGCATTTAATTAGAAGACATACAATTGATTCTTTAATTTTTGAGCAGTTTCA TATTTTGTTAAACAGAAGAATTAATTATAAAATAGTTTGTTTTACATTCACTTGTTTGCT CATCTTTTATTGACTATCTACTCTCTGCCAGGAATTTTGAAGGATACAAAAATGAATAAG ATGTGTCCAGGATTCTTTGTATGCCCACTACTGGCATTCTTACCAAATCTTGCTTTTGAT TCTGCTTCATCGCTTGTTTGAGATGACTTCCAACATTGGACTCAACTTGAACTTTTTGTT TTCTCTAGAAAGGATTCTGGAAAACTAATGAAGAAGGTTAACCAAGTATGAGACATCTGC TATAAAAACCATTAATGGCTTTCAGCTCTCCAATTAATCAAACCCAACATTTCTACCCAG CTTTTAATGCTCTCTAAAATCAACTTCTTGTTTTATATTTAAACCTATCTCCTACTACCT CACAGCCTTACTCCTGGCCTCCCAAATATTAGGTTTGTTTTACATCCTTACAGACAAACT CCCACCATTTCTTTTAACTAGGTTCCATGACATTTTGGACCTTAGTTTATTCATAGGTAA ACCTAGGATAATACCCGACTCCTAGGGAACCATGAAAATTAAATGAAATGACAAATAGAA AGCCCCTTTTAAAATTCCTAACCATAAGGGTGTTGAATGGTCATTGATTCCTTCTCCATT TCAAAAAAGAGAATGTGGTTCACTTATGCAAATATGACACATTTTTCAAAACCAAGACTC TGCCTCCTCAACATTTTTCATAATGACTTTCTGACTTTCATCTCTCTAACAATAGATTTT TGCACATGTTGTCTTCACATTAGAATATTACTAACTGCTATTTTATTTCCATTTATCAAA GTAGCCCTCTATAATACATTTTCTTAGTTTCAAAATGATACAGCTTTCTCAATCTTGTCT TGCTAGTATATTGTAGCTAATAGGGAAGAATCAGCCTTATTTTGAACTAACCTACAACAT CTAACATAGTGCTTGGCACATGACAGATGCTGAATATATTATATAATTTAATTTACTTTG GTTCATGATGGTGGATCTGATAGATCAACAGCTATTCCAGTCTTACAGATAAGTGAAGAT CATATTTATTGTGGGTAACACACCAAGAGATTTATGTGTCTGCTGATCTGAATAAAATAT ACTTGTATTTTAATGAAACATTGGCATGTTATATATCAGGTATGAACTTGGACAAGCACA ATTTTGAAAATTGGATTTAGAGAATATATATCTCAAGATTGCAAATGCTGAAAATAGAAA ATCTTGGGGGGGAAAGAACAATGAAATTAATTGAAAAGAGGGAATAAGAAGATAGAGTTG TTTTAGTTCAGTGGGCCCTGAAATACACTACCCATGTCCCAAACAGTGACAAGACCAGGT TTAATGAACTTGTTGCCTCTTCAGTTCTGAGGGCCTTCTTTAAAAAAAAAATAAATCCAA GACTAGCAATACAAACCTACATAAAAGGCCTGAGAAGCAGCTTGTGTAATGGAGTGTCTC TGAGGGGTAAGTTTCATTAGCTTATAATGAATCAACCTCGGAACTCAGGTAGAATTATCA GAATCTCTGTAATTAGCCACTGAAGCTGTGGCAAATAAACAAAGAGCATATCCCTCTTCT CCAGCACAATAAAGTTTTGTTCCTTGTTCTACACCTATTTCTACCTTATATCTGACAATT TTTTCAAGACTTTTCCCGACTGAGACACCTCCATGCATGACCATTGTAAATTTACAACCG TGCCATTCAGTGCTTTTTCCATCAGTTTGTATTCAGCTCTCCATAATTGCTCAAGAACAA ATACATTCTTCATGTTCAGCTCCTCCTGAGAACGCAGAAGGATGCTGTGGATTGGATAAA TAAGGCAAGATAGGATTAGGGAAAGAGATGGTCAGCTCTGAAGCCACTAGGAGAAATACT TCTTTGACTGATGGAGAAAAATGAAGAAAAAATGAACAGCAAGAAAGAACTGGGACATAA TTGCAGCTCATGCCATTTGTCTTTGTCCTCTAACCTCACCTGAAACCCCAGTAACTATAT CAATCACACAAATAGGCACTCTGTACTTGGAGTTGGACTTTTTTTTTCTACATTGCTTAT TACATTATACAAATTCCATATACAACTCATTGAAATGGTTAGTTCTTTAAGCTTGATTAT GTCAATTCCCAGTGACCAACCTATGAGCAAATCCATTCCATCTTATCCCACACTTCCAAA CCTACCTAATTTATCCTATCTTCTTCCTGGCTTTTTGTCTTTTCTGCTTTTCTTACTTTT CTTGAATCATTAAAAATGTTTGCACACTTGTTATGTGTCAGTTCTTCATCTCAAAGAATT ATAGTAGGAGAGATACAAAAAAAATCACAATTTTATATGATGAATTGCATGATGGTGCAT ATATACACACTCATAGGCTGATATGACCGACTTATGAGGTGTGAACACCACAAGTGAGTG AAAAACTAAAACGTATGTTCAGAGACTTGCAGAGGCTATTCTTGAAGAATCTTACATGCT ATGCTAAAGAATTTGAATGGTACGCTCGAAGGGTAGTGAGAAATCCATTCAATAGCTTTA AAAGGGAACATGATACAGTCAGATTTCGGTTGTAGAAAGATCACTTTAGCAGCTATGCAG AAAATAGGTTATAAGATGGCAATACTATATGGCGGGAGATAATTTTGAGCCTATTAATGA TAATTCAGAAGAAATATATTTTTAAAAAATTAACGAAGGCAATGGCAATATGAATGAAGC TGCGGTGAAAAATTTCATCTGTAGACTTCTTTGATAAACAGATTGATGAAGAATAAGGAA TATAAGATGACTCCAACCTTTCCTATTTAGGAAATGGAAGAATTTGGTATTACTCTCTGA GTCAAGAAGCACAGGTGGGGGAGTAGGTTTAATGCTAACTACTAATTATTGAGCACTGAC TACACCCAAGGAGATGCTAAGCACTTAACGTGCATTATATAATTGTATCTCAAATTAGCA TCATTAATTATATTGAATTTCAAGAAGTCAAGGCTCACAATGTGAAGAAGGTTGTCAAAA ATTACACTGTAGCTAAGTGGTAGAGCTGGAATTCAAACTTAGGAAGATCTGACCCAGAGC CATGCCTCTTAACAAACACTATACCAGTGCGAATTGAAGTGTGGGCCAGAGGCTACTTGC ATGCAGATGATCTAAGGTACTTTCTAAATACAGGTTCCTGGGTCCAACAGGAACCAGTTT ATTCAAACAGAATTCCTGGTGGGTGGGGACTGGACTTACCAGGCATTTTTTATGCACCTT AATCTTTACATACCACTGCAATGCATAGTAATATACTACTGCTTGGTAGAAAGATGATAA CAAATTCACTTTTTTATATGAAAATCTTTAGCATTTTTTCCAAATCTCACATTTATAGAA AAGATGCATACAATAGAAATACCTTTTTTTTTCCTGAGCCATTTGACTGTAAGTTGTCAA CCTGATGCTCATAGCCTGCTAATACTTTAATACCTCCTACAAATAAAGGCATTCTCCTAC ATAGTTACAATTTGACAGTCAAAGTCAGGAAATTAATATGGATCCTTTAGTAGCATATAA TCTTCAGACTCCTGACCAGTGTCACCAGTTGTCCCAGTAATATATTTTGTAGCAAAATGA TCTACTTTGGGGGGCATTAGTTGTCAGATCCCTTTAGTCTCCATCAGTCTGAAATTGTTT CTCAAAATTTTTATGATATGGTTAGATACTACAGGGCAGTTATTTTATAGAATACCCCTC AATTGAGATTTGTCTGGTATTTCCTCATGATTAGATTCTGATTATGCATCTTTGGCAGGA ATATTTCCAAGTGATACCTGCCTCGTTTGGACCCACCCAATAGCTTTAGGAGTGAATTAT TCAGGAAGGAAGAGGGAGGGAAAGAGGAAAAGTTAACTTTTCAGTATGTTGAGTTTGAAA TTCTTGTGGAGCAGTTAGATGATGTCTAATAAGTACTTGAATAGATGGATCTGAGGTTCA CCTGAGAAATCATATCTGAAGACAGAATTTTAGAGTCATCGAAGTGTAAGTGATAGTTGA AGCTGTAAATGGGAATTAACTCAATAAAGGACTTTATGTAGAGCTAGGAGGGAAGAGGCC AAAGGGTGAGAAGACCACGGGTGCACATTGATTTTAAGAATCTAAAATAAGAAGGAAAAC AGGCAAAACAAAGTGAGGAGGAGTAGATGATGGAGAGGTTAAAAAAAATAGTGAAACAGG ATTAGGAAAACTAATGGAGATGAAGGTTGCAGTCCTAAATTAATCCCTCCTGTTGATGTT TTCTTCAAACTGTCCTTGCATTTACTCTTCTTTACTGCAACTGGACTTTCACTGATAATG TGGATTCTTTTATAATTCTTTTAAGTGGAATCTGCTCCTCTCATGTTATTAAATTCACTA TTCCAAAAAAAATTGATATACCATTTGTTTATCTTTTATCTCTGCAAGCCCTTTGTTTCC CCACAGTAGACATGATATTCTTTCTTATCATAAATAAGTGATCTACTGAAAAGTTTATTT TCTCCCAAACCCAAATTTTAAAAAATTATTCTTTAGTAAAGTCGACGTTTTTCCTTATTT TAACCCCTCAGGTGACCTCGAATCCTCCCATTCAAATCTGCTCTTTAAAAAATGAAGGCC AGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCTGGTCAT GAGTTCAGGAGATCGAGACCATCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAAT AGATTAGCTGGGTGTGGTGGCACATGCCTGTATTCCCAGCTACTCGGGAGGCTGAGGCAG GCGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACT CCAGCCTGGGCAAAGAGGGAGAATCCGTCTCAATAAATAAATAAATAAATAAATAAATAA ATAAATAAATAAATAAATAAAAATGAGATACACACCTAGTTAACAGCTGGTTTGTCAGGT ATTGGTGAATAACATCCTTGGGCCTAGTAAATGAGTGAGTATTGCCTACATATATGAGTT AACATAGGACACTGTCCTAGGTTTTTGCCCTTTTATCCCTACACTTTCTCCCCCATTATT CTTATCTATTCTCACTTTTAAATACCTCTGTAAGCTAATGTCTCATAAATATATGATCTG CAGCCTGGCCTCTCCGCTGAGGTCTAAACGCACATTTACTTGAAGATCTCAATGTATAGA AAGGTGGTATAACATAGTGGTTGAGAACATTGACTGTTAACTCATTGACTGGACTCGTGT CCTGACTTTTGAGACTTACTAGCTCAAATTTATTAAATTTAGCAAGTAATAACTTAGCAA GTTACTTAAATGATTTGTACTTCGATTGCGTTATCTGTAAACAAAGTGAATAACAATATC TCCCTCACGGTGTTGTTATGAAGAAATGAGCAAAACATTTAGAAGAGTGTTGAACACATC CTAAGCATCACATATGCTTACTTCTATTATGTCTCATAAGAATATCAAATTTAACATTTC CAGTCTTGAACTCTTGCTCGCTCCACAACTCCAAACCTGGCCTTCCAACTCAGTAAAAAG TACCACCAAACACCTACTTGGTCACTCCAGAAGCCTGCTTTTTATCACTTCTTGTTCTTC ATCTTTACCTCATATCTAGACCTGTCATAAATATTAAGGAGGTATATAAAGCTCCATTGA TTGTTCTTTAAAATATACCTTCCATCCATCCTCTTCTGTCCATTTCCACTCCTCGCACCC CGTATCAAGCCACCAACATGCCTCATTCAGTGACTCTAGTAAACCTCCTACGGGTTGCTC TGCTTCTGCTGCCTACCCCCTTAGGATCCACTATCCACACAGAAGGCAAAAAGAACATTG AAAATGTAAATCAAATTGTGGCAGGCCTCCCCTTACAACACATCAGTTCTTCCATCTCAC ATACTCTATTTCCTTCAGGCTCATGCATGATCTCCTCTGTGACTTCTTCCCCAGCCTCAT CCCCTTCACTTCCCTCTAGCTCATTACATTCCAGGAACAATCACTTTGTATCAGTTCCGT GAAACCCCAAGTTCTACCTCAACTTAGGGCCTGGCATTTGTTACTCCCTTTGCCAAGAAT GATCTCCCTCCCAGCCTTGAGTCCCAAGGTGTAGTCTTTCTTACTTTCTGGGTCTCAACT TATTTTTCCTTCATAGAACTCTGTGATTTCCTTTTGCAGTTTATATGTAATTATATAATT GTTTACTTTTGTAGGGGCTGCCTTTCCAACTAACCTGTAAATGAACTTAGTCTATATAGG GACTCAGCTGTTTAATTTACCACACTATACCCAGTATACAGCACAGTGTCTGTCATATCC AATAACTATTTATTGAATGAATGAATCAGTGAGTAAGTAAATAAAAGATAGGAATATAGA TAAAGTACTCTTTCAGGTTCTGGAGAGCTTTCTTGGAAGCTGGAGATCAACAAAAGTTCA CTTCTTTTTTCAGGAAAGCCATGAAAATTAAGATGTCATTAATAAAGAGGTGTTTCCCTA ACGCCTAAGTTGTGAGTGCTTGCTTTAAAAATACCAGTTCCTGTGCCTGTACTCAGAACC AAAAATTTAGAATTTCTGAAGCTGGAGCCTAGGAAGTAACATTGCCCTTATGCCCTAGGT GATTCCAATGCACACCAGATGCTGTTATCATGAGAATAAAATATATTTCTAAACAAAGCA ATCGGTGTTCCAGGTGCTATCTTCTACCTAGAAGTGCTGAATATGGAGACACCACCCAGA TGGCCATAGGGTGGAGTGAAGCAAATATTTTCCACTAGGAATTTTATGTCAGGATGGTGA AACTCACAATTCTGAGACTTAAAATGACTAGTTTTTCTTCAGCCACCCTGTGTTGGTTTG GATGAAGTAGAAAATTCAAGATGGTGGTGGGATACAGTAAATTATTCCCAAGCCTCCTAG ACTTCTCTTTCCTTCTTCATACTCTCCTTTGGTGGGTTTGAGCACATACCTCCAAATCTG CCCCATGCATGAAATGTCTTTGTGGCTTTGTTTCCCTACAAATGCTTGCAAATTGTTTTT GCATTTTACCCCATAAAATATCTGTTTTTTATATAAAATTACATTGAATTATGTACCAAG AGATGAAACTGATGCTCCAGGAAATGGCATTGTGTTGTTGATGACTCAGTTTACCCTCAA GGACACCTAATCCTCTCTTTAGGCGCATGAGCAACCCATTTGAGAAACAGGTGATTGTTG CCTGTATATATCTTATCTCCACACTAAACTGCAAATACCTTCTTGTATTATGTTATGTTC TTCACAATGTTTTCAACACAGTAGATATCCAATAAATAGCTAACGAATTTGGAACACAAG AGTTTGAAAGAAATAAGGAATCTGAGAAAGCAGGATAGACCTGCAAGAAGCCAGATGCTA TTGGAAGTGCCACCGTAGGAAGGTCCTGCCTGCCTCTCAAGATCAAGCGATCACTTCAGC AGAGAATGCTTTTGGTCTTAACATAGTCTCTCCAAACTCATGGCCTTCAGTAAATGGACT TCAAAGAGGTCTTGGACTTGCATACTCATGCGGAGAAGAAAAAAACTTTTCGAACATCAA ATTAGAGCTTTCAGGATCAAAATGCTCAAACTATCTCTCATGATACCTGATGGAATCAGG ACTCAGAACATTCCCACCTCCATGATATTTTAACTCCCCTTGTTTTTCTCAAGTTGCATT AACTTAAATGCTAACAGCCTACTTTAGCTTTTTTGTAATTAACGTTTTTAAAATCTGTGC TCTGATCTAATTCAAGACCATCTATAAGGTGAAATACTCTATGAAACCCTTATTAGTGAT TTTTTAAAGAAAATATTTTTTAAAAAGCAACCTCCCTACCACTTACAATAATGTTACCTC AGTACACAGCTTTTCTGCAGACATTCATATTCAACCCCACTTGATTCTGTTAGTATTTAT TTCTTGTCCAGTACATGCAAAGTAATAATTGACATTGCTATATAGGAATCTGTTTTTGTG GCTTATGGCTTGGGAATTTATTTGGCTCCTTCTTAAAAACTTGGTCTTCTTGACCCCTCA GCCTTCACCAGTTTGAAAATTCCAACCATAATCCTCTGTGGGGATTTACACAGGTGTCTA TTATTGCCCATAATCTGTGATAGGGCTTCCAGTATCCTTGTTGCAGAAAGGTTAAGCCCT CCCGTCTTTATTCCTGAGTAAAAAAGTCCACAGGGTTTTAGTATTGTCAGGGAGCAGATT GAAACAAGCTGCAACTTCAATCAGGCCCTAAGCTGGTGTCTATGCCAGCGGGGAATCTCT GTGATGAACAAAGGATTCCATTAGAAAACGGAGCAGTTAGTTTTTAACTCCAGAGTTATA CAAAAACAAAACTCTTTATCCTCTACTATTCTTAGGGTGGCCATATTTTCCAAACCAAAA TTTGAGACTCATGTTCTGACAGATGCATAGGTGCTTTTGTCACAACAGTTTCAGACTATC TAATGTTGGGACAGTCCCATAGTATTTAGGATGTAGTAGTCCCACTTTATCCACAGTTTT AATTCCCATAATTTCAGTTATCCCACAGTCTGAAAATATTTAATGGAAAATTCCAGAGAT AAAATAATTCACAAGTTTTAAATTGTGTGCCTCTATAAGTAGTTTGATAAAATCTCACAC CACTTAGACCTGTCCCGCCTGGGACATGACCCATCTTTTTGTCCAGAAGCTCCACACTCT GGATGTTACCCACCCACTAGTCAGTAGCCATCTCGGTTATCAGGTCCATTGTCATAGTAT CACACTGCTTGTATTCAAAGAACCCTTATTTTATTGAATAATGGCCCTAAAGCACAGAGG TAGTGTTGCTGGCAATTTGGATATGCCAAAGAGAAGCTGTAAAGTGTTTCCTTTGAAAAG GAAAAAGTTCTCAACAAGGAAAGAAAAAAAATCATATTGAGGTTGCTAACAGCTATGGTA AGAACAAATCTATCTGTGAAATTGCAAAAAAAAAAAAGACAAAGAAATTTGTGCCGGTTT TGCTGTCACACCTCAAACTGCAAAAGTTATGGCCACAGTGTGTGATAAGTGCTTAGTTAA GAGGGAAGAGGCATTACATTTGTGAGTGGAAAACATGAACAGAAACGTTTCGACTGACAG CGATCAGATTTCATACTATCCTCACTTTCATGCATCCAATGGGGGGTCTTGGAACATTTC CCCAGAGAATAAAGGGGGACTGCTCTGTACTGTTGCTGTATGCATACCACATGTTGGTAC CCAGCATACCAGTTAACAAGGAAGCTTACAAAATGAGATTGCACTACATGGCCATTAGTA GAGATCACTGCCCTTTTTGTCCTGAGGGCCAGTGGGCAACTGGAAACATATGGCCTTGTG GACCTTCCTGTCTGAAGATATACAGTTTGTCTCTAGAATTGTGGTCATCAGGGCTTGTTA GTATGTTTGTGGTGCTGATCTTTATCTTTCAGTCTTCTGAATCTGAAAGACATGTCCACT ATCTTAGATTGTTCTTACCTCTGGTACTGACTTGTCTCTGCCTCTCCCCAATGCCAGTAA CTAAGCTATAAGACCTGAAGGGGGCACCTCAGCGTGACCTGTGAACATCAGCTCCCAGAC TCAGAATAGTCTAAGTGTCTTCAGAAAAGTCACAAAGAAGGGGCCTTCCCATGCTATAGC CAAGCAAGAATTTGGGAGCAGAAGGACTTGAGGCAAGGAGGAGTGGCCGGGAAGTGGCAA AAAGGAACTGGGATGGGGAGTCCCTCCACCAAAAATTATACCTCTGATATAAAGGAGTCA GTCACTAGCCTCCCAGAAGCTTTCTAGACGATGCCCCAAACTTGCAGTTAAAGCATGGTT CTCATGGTTTCAATCTCTGAGAAACGAATAGTAGGCTCTGCAACCAATTTCTACACCCTT TAAAGGCCTTGCGTTGGAAACACCCTAATGGTATCTATCTCAGTCACAGCAGGAACAGGT TGGGAGTGCCATTCCAGAATGCTGCTTCTTGCCTTTGTGTCTTTTTTGACTGTCACCAAT AAAACAAGCAAGGATAAGCCAGATGCAAATGGGTGCAGGACATCTCTGTGTCATTCTTTT TTCATGATTCGTTTAAGTGTTAACCCAAACGCGTCTCACATTCACTTGTGTACATGTCTG CTTGGCATGTAGCTTACAGTTCAGTGGCAAATCTCGCGTAAGAATTCTCTTCATTTTCAA CTGTTGTTTCCAATAGTTTGCCCATAGGTAAAGCTTGGAAAGGCAAAGTCAAAATGATAG CAACCGGAAGTGTTACATTAATATCGCTTACCTGAGGTTTATATATATATATATATATAA AACTCTGAAGGGCTTAGCAGATCTTAGGTGAAAGGATGTTCTTTTCAAAGTGTCACTTTG CCAGAAGAAAGGAAGAAAGACACCTTCCATCAATAGAAACAGTAAAAGCATGCCTCAAAT TGTATTTATCTCTCTAAATTCTGAAAGCGTATTAAGGAAGAATAGCAATATTCCACTTTG GCTACAAATTGCTAATTAATAACTACAATTCTCCCAGAGGTAAAATATTAACATTTTAAA AATGAAATTAAACATCACAATCTTCTTCTAATTGTTACAAAAATATTTAGCAGCAATAGC TGTTTAATTATTTAGGCATTTGTTAGTGGTGTAAATATTATCAGCACAGTCATAAATATT TTCTGCTTTGTCCACAATCAGCTAAGGATATGTTGCTTGTGGGACTTAAATTAAGATCTA TTTAAGGCTGCCTGCTGGCCACAAAATAATTACTTACACTTCCTGATGCCTGAATCTGTT AGATATAGCAGCAAGAAGTGTACTTTGTTTTTGTAAGTCAGAAAAAGTTGCATTTTCTTA TATAAATTTCATTGTTGATGTTATTAAAGAGGATTAGGGTGGGGTTGAAGTAGCTGAAAA TTTAATTAATCTAATCCCTTTAACAGGAATTATTTTCATATTGATAATTCTCTGTAATAA CAGTATTACAGATCACGCCCTGTGAAATATTTACACTAAATATTGTAGCCTGTAATCTCT CCTCCAGCTTTTTCTTTGGGGAAGGATAAGATTTACGGCTTCTTCACCTTTCATCTTTTT TTTTTTTTTTTCCTTTCTCTCACCTGAAGTGCAGGGGACCAAAATGAAATCTTTTTTTTT TCCTGCTTCCTCTTTTAATTTTCTGTCAATGTCATCATATCTCAGTAAGTTATGTTAATA GCCATCAAATCACTAATCTCCTAAAAGAGCACGAGTGTTATGAAATAAGGAGAACAATTG ATTTTTTCCCCTCTTTGGTATCTACAGTCATTTGGTGTAGATTCTCATTTGAAATGATTT GTTTACCCATTGATTTCAATAAATTGTTATGCTGCTGAAAATATCACTAAGAGTAGAGTC AAATGAAGGACGAAACTGTCATTCTGATCAACTTCCTCTGATCATCTCCGGTGTAAATTG GGAATTGTTCTCAATCAGCTCAAATGTCATGTTATCAGGGAGACCTTCTCTGACTTCCCA AAATAAAATTACAATCACCATTGCTTCCTTTAATTGGCTTTATTTTCTCCATACAAGTTG TCATCGTGTAACATTATAACACATTATGCTTGTTTGTTTAGTGCCTGTCCCCCAACTAGG ATGGAAGTGCCACAGGAAGCAAGGACTTGGATTTGTTTATTGCTGTATCTTGAGAGCCAA GCTGAGTGCCTTAAATATGGCAATCAATAACACATTGTTGCATGTATGAATCTTTACTCT CATTTTTTTAGGTGCCTGAAGCACCAGATCTGTGCCAAGCAATGAAGAACTTGATACAAA TGTAGACATTTGCCCTGAGCTGGCTGATCCACTCAGCCTCAATGGAAGGGTGCCCACTGA GAACAGACCTGGTGCTTTCTGTAGCTATGCCTTCATTAAAGAACTAAAACTGGGTTGTAT AGTGCTGTTTGGCCTCCTCATGTTTACAATATCCAGTGATACAAAGCAGAGAATCTTTAA GGATGCCCTCCAGGATACGACTTCTGTAGAATATGAACAGGAGTTACTAAACTAGAAAGA GACTCCGTGGTCACATAAACCTATGTAACTAGGTATTATGTGAAGCTAAACAAGGTTCTT AATTTCAAGGTATATCAGATTATGATAACATTCATTAGGACTCTCCAAGACAAGAAGATT AGGCTGTGTTTCCTGAACTTATTTGGTCTTAGACATTTCCTCTCTACCAGCCAATCCTGT TTCTACAACAGGGCTACAACAGAGGGAACTCCAGTGACTTGGGAATTCAGCAAGCCAGGG AAGGGGTAAGAGGCACCAGTCTCATCACTGCCTCTTACTGACTTTATTATGTGACCTTGG ACAAATTACTTAACACCTCTGTGCCTCAATTTCCTCTTCTGTAAGGTAGGGATGAAAAGG ATTACCCAGGAAAATGTACGTAGTGTCCAGCACGCAAGTGCTAACTAAATGGTGGTTATT GCCAAGACTTTATATTAAGTATAGGCATGAGAGCCTTTTACATAGATTTCTTCAACCATA TTTTTTAAAATAGGTTTGTTAGTATTGACCAATTTCCAGAAGCAGCCTAATGTGTCATCT CATGTGGCCCCAGTGCCCTATCCCTATCTGAGAAGCTCTGCACACCTGTGCTGAAGGCAA ACAAATGTTATCTTTCAACACAACTTACTACAAACATCTGATAACTCACTTTGGTGGATC CCACAGCGCCTTTCCCCTTGTTTCCATACCCCTGACCTCAGATGAAGACACTTTTTTCAG GAGGAAGATGGCAGCATCCAAGTTAATGATAGTGCAGATGGCTACATGCTGACAGATTTT GAAGTGACCATATTTTTTCAGTAAATTTCAAATGAAGGTGTGATTTGTGTAAATCTGACC TCTTCCTGTAAAATGTGCATTTACATATATTTAGAATTTATAAATCCTGACAGATTCCAC AATATTTATAGCCCTCCATAAAAAGCCTTTGCCAGTCTGTAGAGCTTTGCATTTGGCTCT CTGGCATGCTTAAGAGAATTTAAATAATAATAAATTTGGTGATTTATTCCACCTGGAACA GAAACTTATTTCCCCCCTCCCCTGGCTCATTTTGAAGGGGATACTATAAATAGTGCCACA GACGCTGGGATCAGGACTAGGGAATTGAAATTTGAGAGAGAAGTACAGAAACATTTTCAT TATCACTGATTCCTTGAGTGTATTTTTAAAACAGTTCTGTTCCTCAAATAATGTACCTTC TCTTCTTTCTCCTGCCCTATCACAATTATACTTGAATCTCCAAAACCTGTTGCCAACTTT AGGATTCGGTTACATTAATGGGAAAGAGAGAGTGAGAGTATTAGCTGACTAGGTAGGAGA AAGTTGCCTCTAGGGAGACCAAAGCAATTCTCCCATGTTCATCTTATATTTCATAGGAGT CAGCTAGTAACTGAGTGTCAGTGTCTAAAGTGTAAATTCATTATCTGAGACCTCGCTCCT GTATCCTACAGGTATGATGAAAAGCTCACAGTATATGGAAAAAAAAAAAAAGGAAAGAAA GAAAGAAACCTAATTGTAATTACAAAAGGAAGCCCAAGGACAATGTCCGAGGATCAATTC TTTTCACCCAGCCATGCTCATAATAACTGAGTACAGAATAAGAAACACCTGAATAGTCAA GTCCTAATGATACTACTTGTTTTCTTAAAAACAAAATCAACAAAAATCTGGTAACTTGTC ATTTGCCATGGAATCTACTGATGAAAGCTGAGAGTAGCCATTTAGTGTAGCATAAGCAGT GTTGTAACTTGTAATATAACTAGGAGATTTATTTCTAGCTTCTTGTTTGAATGTCTGTAA AGGAAGTAGCATTTGTTAAAGGTAGAATAATAATAACTAACATCCATGAAGAACTGCCTG TGGGCAGGCACAGAGTAACAAACACATCAAGTGGCTGTGGTTTGATGTGCAACAGCCTCC TAACTGAGTAGTACGTTTTCTTGTCCTGATAACTTGGAGCACACTCCCAGCCCCAAGACT TTCCTGAACAATCCTTTTATCTCTACCTAATAGGCTGGCAGGTATTTGGACCAAGCCCCA GAGCCTTTAGGGTACCACATTTTAATAATTGGTGGTGAACAAAGTAAACGTTGTAAAACC AGACATTATGAAGCAAGGACCCAGTTAAGTATGACGGATTTCAGGGAAAGCCAAAAAAAA AGGCTGAATGTTGTATGGGGGTATTGTCTCCCCTACAGAACACAGGTATCTATGGTTCAT GGCTCATTCTAAAGCTTTGCTTGAAAAATGACTTTTTAAAGAAGTGTACTCTTAAAGAAT GTCCTTCAGGCAGGGAGGAATTTCCCTTGCTTTTCTATAGCATCTTTGTAAGAGGAAGCG GAGGTATTGAGCTGTTAGACAGTTGCTCGGTGCCTTCGTGCTTCTGTGACCACATTATGG GTCTAACACATATGGGATAAATAAACTGTTTTCATTTCTTAAAGCACATGGAAGGAAACA AGACAAGAAAATTACCATATTGCTTTTTTTTTTTAAAAGCTATTAAAGAGGAGAATCCAG TTAGGGCAAATAAAAATGATTACTGAAAACAGATTTTTTTTTTCCTTTTCTAGCCTCTTA CTGAGCAACAGCAATATGGCAAGACTTGTGGCAAACCAGTGTTTTGATGCACGCTCTTTT GTTCTTCTTCCATAGGGCAATCCCTACATGTGCAATAATGAGTGTGATGCGAGTACCCCT GAGCTGGCACACCCCCCTGAGCTGATGTTTGATTTTGAAGGAAGACATCCCTCCACATTT TGGCAGTCTGCCACTTGGAAGGAGTATCCCAAGCCTCTCCAGGTTAACATCACTCTGTCT TGGAGCAAAACCATTGAGCTAACAGACAACATAGTTATTACCTTTGAATCTGGGCGTCCA GACCAAATGATCCTGGAGAAGTCTCTCGATTATGGACGAACATGGCAGCCCTATCAGTAT TATGCCACAGACTGCTTAGATGCTTTTCACATGGATCCTAAATCCGTGAAGGATTTATCA CAGCATACGGTCTTAGAAATCATTTGCACAGAAGAGTACTCAACAGGGTATACAACAAAT AGCAAAATAATCCACTTTGAAATCAAAGACAGGTTCGCGTTTTTTGCTGGACCTCGCCTA CGCAATATGGCTTCCCTCTACGGACAGCTGGATACAACCAAGAAACTCAGAGATTTCTTT ACAGTCACAGACCTGAGGATAAGGCTGTTAAGACCAGCCGTTGGGGAAATATTTGTAGAT GAGCTACACTTGGCACGCTACTTTTACGCGATCTCAGACATAAAGGTGCGAGGAAGGTAA GAGAAAATCTGTCTGCCTTCAATGGGAACGGGTGTGTCCAAAGAAAATGCCAGAGTGTCT CACAGCTGTAAAGTGACATTTGTCAATTTCTACTGCAACGTTTTCTTCAGGAACTCCACT GTAGAAGTAGGTTCTGAAGGCATTCTGAGATCCCTCATCCTCAGCAGTAATTTGTAATCC CAAACTTGCTGTCCCTGAACCTGGCATGATTCTTCAGAATTTAAATAAAAGTGAATTTTA AAAAGTAACTCCCTGAGTCGGGAGGTCCTTTAGGTCTTTAAGGCAATGAAGCCAGGGGAA GCAAAACCATTTGCCCTATAACGAACTGAAAAACTAGAAATACAACATACCATTGTTTAC AAATGCAAAGCAGGGATTCAACATGGTACAGCAGTCAATTTATGTTTTGTGTAATATTGC ACAAAAAAATCTGGAAACTAGAGTTATGTTTCTTTAAATTTATTAAATCAGAATCAATAG CATGTAGGAAACATTTGTTAAATTGGGACACGCTCTACTTTTCATGTTTTTGGATGTTAT TATATCAAAAATATATACTAGCATTTAAAATATAGACCTGAGTTGGGCTCCCTTCATCTT GTAGATTAATCACAAATGGACAGAGTTTAAACACATTAATTAAACACAGTCAGGGATAGC TTTGGTTTTGATAATATACTAGAGACAGAATTGAGCAAATTTCCAAGAATTTTGAAGATG TTTAAATGAAAAACTTCAATAATGAGAACCAGAACCACCACATAGGGATTTTCAACCAGC TTTTTAAGTGTGGTATATTATCAAAACGACCACCTGATGGGAGTGGAAGCATGAGATAAT GAGTGGGAAAAGTAAAGGTAAGAGCAGAGTATCTAGCAAAGGGAAAGGCAAGCAAAGAAA TAACACCCCAGTAAAAAGGCCAAGATATCTTTAAATTGAAACATATGAGGATAAGCATAT AAATAGTATATATCATGTAGGTTTCATTATTTAATGATAAAATTCAAACAGATAAGGCAG GATTGATTCAATTTATTGGCTGCCAACATCCTTTAGGCAGCCCAGTTCTCAGAAACTGGA GAAGTGTTGAAACTTTCTGGTCTGTTAGAGATTTGCCTTACCTATGTGTGCTGGGAGAAA GGTCACTGCTGTTAAGGTAAAGACCATAGTGGGAACGCAGAATGGAGTGGTGGGCTTGAT CATAGTGTGGTGTCAAAGGTTTCAGAGTCTTAGCTGTGGAAAAGCAGTAGAAACTGGTGG CCATCTACTCTCAGCTTTTTCTAGCTTCATGTTCCTCATGGAAGAATCAAAAGCCTTTAT CTGCGAAGCTTTTCCTAAAATTTTGACCAAGATCTTGGTGGTATATAACGAATATATCTT TAAAGCAGTATGATGTTGAACTTGTGAGTTCTAAGCTGTAGAGGATAATTCATGTATTAT TAGCAGAGTACATGACAGGGCAATACAGGAGCTGTTGTCTTAAACATAAGTTTGCTATTT ATAGTAATACACAGCCATTATACTTATGAACATTTTAGCAAAAGACTATTAGTTTCCAGG ATCTTATTCTTGGGGAAGTATGATATATGAAAATAGTTGATATTGTTATTATTAATGATA GCTTGCCACAATGAAGTAGCAAATATTCAATTCATCTACATGAATAATGGTAAAAAATTA ACAAACTAAGATGTGGATTTTAATCCTAGTGTAATCTACATTGCTCGGTAGATTCATCTA GGTCAATTTCCTTGCAGTTTAAAAAATACTTAATCTGAGCCCAAATTCCTATTGCTCCAC CTCCCCATATACCTTTATTTGCCACTTGTAAATAAGGCAATCTTCTGAAGCATTTTGGTT GGGAAAAACCTATTGCTGATGCTTATTTTTGTTATTAGTATTCATTTTGTTTCCTCTAAT AATTTAAAAGAAAGTGTAAAATAAACTTGAAAGCTAAAGGCATTTTTCTGCATTCTCCAC TGATGTCAAGCATGCCATCTCCTAAAGGTGGTGTGTTGGAAATGTAGATTCCTTCATATC TATCACATTTCTCCCATCTCCCAGACTAGTCATTTCCTCCAACTGCATTTCAGTGGTTCT GAGGAGTTTGGAGGGCTCCTCCCTCCTTCTCTGGACTCAGCTCCACTGTCTTTTCCTGTT CACTAGTCAACTGTAAGCTGAAGAGAAGCAGCTGGGCAAATGAGAAAGGTCCAGTAGAGG TGAGCCCCTTCCATAAGGTCTTCTTCTGTCACCTCCAGACTTTGTCCAAATCCTCAGGGC AGAACTGATGCTGGCATGTACTGCACTAGGCACCAGATGGCTGGAGTATTTTTAGTCTTA GGGGAGGGACTAAAGAAGCAAGGTCTGATGGCTCGGGCGTGTCTCCAGCTTTTAAGTTAT ATAATGAAGATCTGCTGATGATGGAGCCAGTGAAAGGAAATGTTGAGCTATAGTCTGGTT CAGGGGCCTTTCAGCATAGAAGCTGATCTAATTATTTTACTCTTGAAAGTTTCAGTAAGA TTAATGGTCTAGATTGTCTTTCTGTTATATAACAAATCATCTATAGAAGGATTAAATATT AATTGATAATCTCTAAAAGAAAGTTCTAAAGTTTCCCTTTCAAGGCTCTCATAAATGTAC ACTTTTCAAAATACAACTGAAGTTCTTGTTCCTTGCACCCGCCCCCACCATCCCATGAAA TGATTGCAACATTTAACATGCCTTTACATGTCTATATCTGATCATGATAATGATATTTTT CTACTTGTTACTTCTATCCCCACCCCACCATAATGTGGAAATTGACATAAGTTATTTTGG AAAAGTAGAATGGAGACCAGATGTAAACATCTATAGTATAGTGGACAGAGAATTCAAAAT TTTTTTACCTTGAAATCTTAAACTGTGAGACAGTTGATCTTTGCTTAAGATGACTGAGCT TGTGAGATCCAATTCTCCGTTTCTTTGTGCATATGTTTGTTTTATACTGGCTAGTGTTTT TTAATGGAAAAATAGTGTTTTGATTGACATTAGACTAATGTAGCATTTATGTTCTTTTTG GAATGTGATACATCTGATACCTATTTTACTAGTAAGAAAAAAGTGTAATCTCATCATAAA AAATTTATTCTTCTTTTGCCACATACTTATTTTGCTTCCATTTACTCCCTCTCATTGCGT ATTTATTAAGATAATGAAGGAAAAAGAGGAAACATGGCTGTTGGCAATTTCAGCAGCTCC GTAGTACTTACATTGTTCAATAAACTTAATAATCTACATGGACTAATTCTGACTTATGGA TGTCCTGCTTCAGTAAATCACGGTGATTTTCTCCAGTGAATAACAGACGAGTGCAGTGTG CCAGTACCTTAATTAAAGAGCGGCTCTCTTAGTCTTGATCTCATTTTAATTTACAGGGTA ATACTACAATAATATCACTAATGGAAGGTACATTAAAGGGCATCAAGTAGCATTAACTGT ATTAAATTATGGTACTTATGTTAATTAACTGCTGAAGCAAGATGGTTCTAATGGCCAAAA AGGTCATCTAATGCATAAATAAAATCTACTCAGATGAGGGGCAAGAGGAGAAATTAGAAG TAAATGTTTGTTCTGAACATCTTTTTATACAGACAGGGGGTTAAACTCAAAAGCTGTTAA ATATAGATAATGTCCAAAATGTTTTCTTATTTACACCATTGGAAGCTTTGATTTTTAAGT ATTTTGTTTCTTTGCAAGCTTTCCACAATTAAAATAATTGAAAAAGCGAGCACTGTATTT GTCAGCTGCATAGATTTTATGAAATATAAACTAAAAATTATTTATTATTTCTTTGAGGTA AACAATTTCAAAGAAATAATGTGATTTAATGTAATAATTTATAAATCTGAAAGACAAATG AATCTTTAGTAATCTACTCATTTATTTTTAAGATATGCTATCAGCCATATATCAAGGTAC TGATTTTAGCCATAAGACAATGGAAATTCTATTTTAACAGTAAGAACTTGAAGAAAGTGG ACTGGAAAACTCCCATCAACATCTTCAGTATTTACCCTTTAACAAAATATTCCTGAAGGT AATTATCGGTCATTTTTTCTCAATGGTCATTACACATTTCTTATCCCTTGCAGTGCCTAC TCAGGCTCCATTATAGGTAGTTGACTGCCATAATAGTGAACAGTATTTTTTCCTTTTTCT ACCTCCATTGTTTACCTCCAAGAAAGAAGCCTTGGAATATTAGCACAGAAGTTTCACTTC GACAAAACTTTTTGGTGCCATCTTCACTTCATGGCTGCCCCTGCTCAGAATCACACTCTC CCTGCCTAATCCCAGGACCTGCAAAGGGCCAGGACCAGAGCCACTATGACTAGGTGCCAG GAGTGAGGCAGGCCCCCTACGTCACTCTCAGGAGTCCAGCTTCTATGTGTAAACCTTATT CTTTGAATGTCACTGCCTTTATATTTGCTGTAATTAGAACAAGGTGGAGCTGACATCGTG TTCTTGAAGCACAACTTCCACATGGTTAGTGCGAAAGATGTGATGTCAGGCAAGCAAGAA CACTTGGGGAAATTCAAAAGTATAAAAGCAGTAGAGCACTTTTTAAATTTCTGGAAAAAT CAGTTATTCTGAAGGTTCCCTAAGTCTTTTTCCTAGCCACAACTGAAATAAATCTGAAAT ATTTACTTTTTACCTCTTTTGTAAGAGACATCCCACAAAAATGCTTTTAAAGCATTGAGC CTGGCCTTTATCTATTCTTTTCCAATTAGTCTCAATTATTGAGGTTGGGCTTTACTGCCA CTTAACAGATTCTGCTTTTTATAACACCTTCTTCCTTTCTGTCATCCATAAATACTTATC CTCTACTCTGGGACAGATGCTGGCTTTGATGGTAGACAGACGAAGATGCACCAAGCATAG TCTCTGCTCTTAAGGAGCTGATATCCAGAAGGGACACAGACTTTATAAACAACAACGACA AAAAAAAAATGATGATAATGTGGGTTAAGTGATTTTACTGTGTGAATATTCAAAGTGCTG TGGTAGCAGAGAAGCTACTAATGTAATCTGGAAAGATTAGTAAAACCTTTGATAAAGATG TGACATGTATGATGTCTTGAAATATGGGTTTTATTGTGCCAAGCAGCCAGGAAAGAATGG ATATCCTAGGCAGACAAATTATACCTAAAAACAGCACAGCATGTTAAGGAACTCCAAGCA GTAAAGAATTGATGGAGTTAAGAGTCCTGAAGATGTTCTACCATCTTCCCTTTATGGGTC TTCAGCATGTTCAGGAAGCTCTGAAGGATTCCTACCTCTTTCTCTCTGATTCTCCCATGC CATAAGAAACCCAAAATCTTATGGAGTCTCCGTATTAATTGACTACAAGTGAGGAACAGT TTTTAAGGCAATTGTAGTAAAGGCTATTCTGGTGTAACTGTGCAGACTGGAAAGCTATAA CATTGCTTAATTGTGGAGCAACTATAGCTCCAAGCCCTGATGCTCAAGTGGAGAATCCAG AAAAGCTCTCCATATTCCACAGGAGCCATCATATGGCAGTGGTCTCAGATTTGCTTACAA AGTCAGTAGGACTTGTTGACCAGTCAGATTTTGGGGAAGACTTCCTAGTGAATTGGATGG TGGGGCCAAAACTAAAATGGGGAATAAATACTGAAACAGGCTTTTAGTTAATTCATGATT TAGCTAGTTATTTTGTTGTGCCATTTCAAGTAGTAGAAATTCAAGTAGAGATTCTAGTTA GGGATTTGAAAATACTTGTCTAGTGTTGTAGAGAGAGATTTGAGCTCAAATATAGGTTTG AGAATTATTACCTTATGTGTTATGGTGGACTCTTTGAGAATCGATGACATTGAGGATTTT TTTGTTCATAGGTATAAATGACCATTATAGAACATTTACAGAATCCTGTGGAATACTACT ATGTAAAAGGTAATTTCTGAAGGAAATTGAGAAATAATCTGAGAAAATTCAAAGAGAAGG GAATGAGTTAATGTCATTCTAATAGTCCCCACTCATATTTAAGTAATAATCCTTTAAATT TGTATAGCATTCAGTTTACAAAATTCTTGTCAGGTACCTTATTTCCTTTAGTACTTACAG GACACTTGTGAGGCAGGTGTTGGTTAACCCCATTTTACAGAGGAGAAAACTGAGGACCAG AGGAGTGCCGTGACTTTTTCTTTAACGTCACACATAACAAAGTGGTAAAATCAGGTTTTT CACGGCAAACCTTAGGCTTTTTCCAAGCATTATGCTCTTACAGTCACACCAGCCAGAGAT CAGCTCAGTATATATAGAAGACCCCAAAAATTCCCAGAGAAGCCATCTTTAAATAGCAAC AATGAATCAATACATCTTATGACTCTGCCCCTCTTAGAATGTTCTGGGAGTCACACTCTC CATGGCTTTTGGCTCAGTATTTTATTACACCAGGCTGCTCTGTGTTTATCTGAACTCTAA CTTCTTACTTCATTTTTATCAACTTTCAAATGTGTGATTGGGCTCATTTGTCACATTGTG TTAAGTCTAGGTGTTTTACTACTAAAATCAAATTGTGATGATAGCTTCTTATTTTTCCAT GGGGAGACAAAAATAAATAAATAAGCTGTATTTTCTCAATGTTAATTTTTCTCCCATATT TCTTCATAAACTTTTATTATGTACACCTGCTTTCAACTAATGGGCATCATCAAACACTAA AACAAGTCATATATCTTAATGGATAAACTTGGAAATAGCCAACTACCTTCGCTTATTTTA AGCAAGTTCATACTTCAAGTGAGGGCAATATGTTTTTCCTTTAACTTCCACATATAAGTC CACATTCTCTCTTCTGAAACTATTTTGAATAAGTGTGCTGCCTCTTTCATATAATAAAAT TTCATAAATTTTTAATCAATGATTCTCTCCACCAGGTCTTTTTTTCAAGCTAAATGGATA TTAAACCATTCCACTAAAATTTAATTTACTCTCCTTTTAAAAGGCAGAATGAAGTCCAGT AAATAAGAGTATTCAAATGAAAAGCATGGTAATCATAATTAAAAATTAAAAACCAACATA AAACATTGCTACTTAACTCCAGTGGAAACATTTAGAATAAAGACTTTATCGTATGCACCC ATTGTAAGTGGACAACTGAGGGACATTCTGATTTGGAGCATATTTTTAAAATCTATTAGA AAATCTTGAATTATAAAGAGAATATATGCATAAGCAGCTCATTTTCCTCTGAGGTTTGTA CTATTATAAGGAGAGAATGTATCTAATAATTCCTCCATTTAAATTATGAAATTCATTAGC ATGCAGAAAAACAATCCGGTTTAGGAGCTTGTCTCTTTATCCTTAATTCCCTAGTGCCAT AGATTTTTTAAGCTAGTGGGTCGTTAAAGGGAAGATGTCTCTTTTTTAAGAAACATAAGG ATATTTAAGCAAAATACCACAAAATGGATAAATAAAATAATTTCTTCCCTCATTTAACTT AGCATTTGTAAGGGAAGCTACATTCTAGCTACATCTGCATGCCCAAACAATGGGAGGCAG CAGTACACCAGCTTCTGCAGCCCTGTTTTTTATCCTAAATCTGTGGTCTGCATCTTTGGA ATGTCTTGCTGTCTTTCTGTACCTAGGATCAGAGTTTTTTCTTAACACGTTAGGAGATGT TGGCCATTGTTTGATACTTAGTGCAAGAGTTTTTTGAGACCTATGTGATCAATGGTTCAG TAAAGAGACTATTTCCATTCATTCTCCAAATAAATACAAGAACAAATGAATTTTATCACA GTAATTTGATTGTGTGGATTGATATATTGATTCTGTTGCAATATGGGTCTATATTTTCAA TTCAATAAGCCACTTTTAGAACTAAGTATATTAGTTTAACCAGAAATGACTGCACTGCAT AAAAACTCATGGTTACTATTTCTACCTCCCTTTTATAGGTAGGAAAACTACATCTAAACA AGGTTAATCAATAGCAAAGGGGAAAGGAAAATTTAAAAATTACTTATGTTGGTGTATAAA TTTGTTTCTCAACTCCCCTTGAAAAACATTGAAAAAAATGGATGGAAAGGCTTTGAATAT GTGAAACAGGAGCCTCACAAACCCTACTGGTCCAGAAGATTATAAAAGTAGGGTAGTTAC TACACTGGCTCTCTCTTGCATTGTGACTGGTACCTAAGACAACTGATATTGTGCTATAAA TATATTGAGAGGATAGAGGACAAGTCATTAGGATTTTAAAATCATTATCTACCTTATTTT AGAAGGAAACATTGGCTAAGAGTCAAGAGAAATAGATTCTCACTCTGGTTGTGCTAATAA TTCTTTGTCAGCTCAGAATAGGTCACAGTTACCATAATCAGAGTCTCCTCATCTACAAAA TGAGATTTTTATACTATTTTACTGTTTCTCAGGATGTACTCTTCAAATAAAGTCCATGAT GGTCAAAAACATTTTGGAAGTGTTCACAATACTTCCTTCTATGAGAATCACAATGTATAT TCATATATTAAAGACCCTGAGGTGTCCTACAGTAAAGAAACATTTCTATTTTATTGAAGA CAGAGCCTCTAGAACTTACTTAGTCAAAAAACATATATTAGTACCCATAAACGACTAGTA TTCGCAGAACTCTTTAAGCTCCAACATTGTTGGACTCTTTGTAAGATTGAAGGAAATACA TGAAAACATCGTGTGTGTGTGCATGTGTGTGTTTGTGTGTGTGTGTGTGTTTAAACTATT TGCAGTGCTAAAAACAGATTGATTTTTCAAAGCAAGTTCCAACTTTAGTTATCATCCTTC CTATATTACTGCTACTTTGGGTGAAAAAGTGAGACTGTCGTAGAGAAAGACTAACCTCAA TGAAGAGTATCTCTTTTTTTTTTTTTTTTTAACTGTCGCTCTTATTTTTTGAACCTTGGA GTACTATGCATCCTTCTTTAAGAATTATAGGAAATTAAGTACTGTATTGGAATAAATAGG GATTTTTTTGTTTTGTTTTTAGGCTAGTGAAATTGTGATGGAAGAGTCAGCAAAGATGTG AAAAATGAAATGCCAAGTGGTACAATCTGGTGTATTTTGTAGATAAATAGAGATGCTAAA GGATTTTTATTCCTCCCATATGTAAGTGCCTCAAACTCTAATTACAGCAATGAGCTAAAA TCATGTATTGAAAGAAAAATTAGATTAACCAGTATTTAATATATTCTTTTTTTTTCATTT GCTTTGGAGGATATTCTTGAAACCACAAGCTAATTTTAGTTAAATGAATCTTGCCTTTCT TTTGCTAATTAGGACTGTTAATGAATAACAAATCAGAGCCCAGTAAAACTGAACATTGTA TATAGCTAAGGATATCACCTTGTCTAGGAATTGTGTTTTTGTCCTGGCCGCTTTTACTCA TTTGGTGCTAACAGAATATCAGGGAAGCAAAGCTGTTATAACATATTGATGACATCCATG TGTAATTATAGATACTCCAGTGCTGCTGGGAACAGGGAACAGATGGGGGAAGGGTGGGCC AAGAGATGATGGGTGGGGGAAGTCTAAGAGGTCAGAGATTTGGCAGGTTGGAAGGAGACA GCATCATTAACTCCAGTATTGGATTTGTATAGACAGGGTGTACGCCACATAGAGTCATAG CATTGCAAAATCATTTCTTTTAGAACTGAAAAAAAAAACATAAAAATAATTTAATCTAAC TCCTTTTTCAGATGTGAAACAGAATGGTTAAATGAATTAGTCAAGGATGACACTGTTGCA TAACTAGAATTTAGACTCAGAGGGAACTTTCAGTTTACTCACTGATCTGCGTCCCGTGCC TACAACTAGGCCTGGCGCATATTAAAAGTTCAATAAATATTTATTGATGGAATGAGAGAA TGATTGCAGAATATCCTTCTAAGCATCACGTAGAGGACCATTCTGAGGACGGTTTTCCCA TTAGGTATGCTATGGCCACCTCTAAATATTCCCCACACAAGACTGCAAGAGAATTGGAGC TTAGCCCATTGTTTTTGGCTATGTCACTTCATCCAATCAACCAGATCGCAAAGCTTCAGG CTTTAACCAATAGTCCAAACTTAAAGAATAAAATATATCTACTTCAGATAACAGAGTAAG CTATGTACTTGGGTTAAATGAATACCACTCCACTCAAATACACACAATTTCTTTTATTAT TTGTTTGATTGGTCCTTTTAAGATCAGAAATTGTGATCCTTAATCCCTTTCCTGGATGAA GAGAAGTCCATGAAAAGGAATGAACTGCTCTCATTCTCAAGCAATATTTAGTAAAATCGC AATATCACTATACATCCACGTCCCAAAGTTGTCTTCAAATGATGTTTGCTTCTTGAGTTT ACCAACCAAAGGGACTTAAAATGCTATTTAAAAACCTTACAACTTGTAAATGATGCCTTT ACATATTGATAGGTTCAAAGCTGGGGTTTCAAAGAGTTTGAGCTGAGGAGACATGGAAAC AGGCAGTGGCCAAACTCAACTATATACATGTATCTGCTGAAACTTTTATGAACATATGTC TTTATGAAAATAATTGAAGTTCATTATATACTCTTAAGTGGCAAAATAGGATTAAAAATA TTAATAGCGTGAGGCTAATTATGAGAAGGAGGAAAAAAGAGAGAATGAGACAACACAAAT ATAGTTGGCTAATAGTGGTGGAATTGTGAGTAATTTTTATCTAATTAGTTATGATTTTCT ATTTTTTTTCATTTTACTCATTGTATCGTCAGAAAAAAATAGTTTTTAAAATTAAGTTAA AATTCAGCAAAGTTGCAGGATACAAAAGCAACACACAAACATCAGCAGTGCTTCTATACA CTAACAATGAAGGTCCAACAGGAAATTAAGAAAACAATTCCATTTACAATAGCGTAAAAA TAATAAAATGGTTAAGAATAAACTTAACCAAGATCCAAAAGCCTTGTACACTAAAAACTG CAAAACAGTGCTGAAACTAATTAAAGAAGACACAAATAAATGGGAAGACATCCTATGTTC ATGGATTGGAAGTCAATGTTGCTAAGATGTTAATACTACCCAAAGCTATGTACAGATTTA ATAGAATCTCTATCAAAATCCCATTGACGATATTTTCCGAAATAGAAAACTTCATGCTAA AATTCATATAGAATTTTAAGGGACCTGGAAATAGCCAAAATAACATTGAAAAAGAAGAAT AAAGTTAGTGGCGTCACTGGGGTTTTTATGTTGTTGTTCTTTTTTTTTTTTTAATTTCAA AACTTACTACAAAGTCACAGTAGTCAAAACTGTGTGGTACTGACATAAAGATAGACATAC GAACCAAAGAAATAGAATAGACAGTCCCAAAATAAACCCTCACATGTATGGTCAAATAAT TTTCAACAACGTTGCCAAGACCATCGAGTGAGGAAAAGACAGTCTTTTCAACAAATGATG TTGGGAAAACTGAACAGTCACATGCAAGAAAAACAAACCAAAAAAGGAAGTTGGACCCTT ACCTTACACCATATACAAAAACTAATTCAAAATGCATTAAAGACCTAAATGTAAGAGCTA AAACTATGAAATGTTTAGAAAAAAACAAAGGAAGAAAACTTCATGACATTAAATCTGGCA ATAATTTCTTGGATATAACATCAAAAGCACAGTCAACAAAAGCAAAAATGGGTAAGTTGA ACGTCATCAAAATTAACAACTTTTGTGCATCAAAGGACACTGTCAACAAAGTGAAAAAGC AACCCACAGAATGGGTGGGAATATTTGTAAATCATATATTTGATAAGGGACTTTTATCCA GAATGTATAAATTACTCTTACAATTCAACAACAAAATAATCCTAATTAAAAAATGAGCAA AGGACTTAAATAAACATTTCTCCAAAGAAGATATATAAAAATGGTCAATAAACATAGGCA AAGATGCTCAAGATCATTAGTCATTAGGGACATGCAAGTCAAAACCACAATGAAATACCA CTTCACACCCGTCAGAATGATTACTATTCAAAAACATAAAATAACATGGTTGGAAAGGAC ATGAAAAAATTGGAGGGTTTTTGCTATACTAATGAAATGGTACAGACACTGTGGAAAACA GTGTGGCGATTACTCAAAAAACTAAACATAAAATTGCCATATGATCCAGGAATTCCATTC TGGGTATATATCCAAAAGAAGTTAAAGCGGAAGCTTGAACAGATATTTGTACATCCTGTT CATAGCAGCATGGTTTGCAACAGCCAAAGGTGGAAGCCACCCAAGTATCCATCGATGGAT CAGCGGAAAACCAAAATGTGGCATATACATACAGTGGAATTTTATTTAGCCACAAAAAGG AAAGAAATTTTGACACATGCTACAACATGGATGAAACTTAAAGACATTATGCTAAGTGAA ATAAGCCAGTCACAAAAGGACAAATGTTACATGATATGCAACTTATATGAGTGTCCTAGA GTAAGCAAATTCATAGAAATAAAGTATAATGGTGACTGCCAGGGGCTGGGGGCAGATGAA AAAGAAGATTCATTTGTAATGAGCACAAAGTTTCAGTTAGGGAAGATAAAAAAGTTCCAG AGATGAATGATGATGATGGTTGCACAACAATGTGAAAATATTTAATGCCACAAAACTGTA CATTAATAATTAAAATAGTAAATTATGTGTTATGTGTATTTTAACAACAACAACAAAAAT AACTGCACAAACAATACTCCTTGACTCAGCAAAGTAAAACACAGAAATTCTGACATATAT CCATGTGTCTTTCTTCTCTGTCCTTATGAAATCTTCTAGTCTTTTCCCACTTTTAATGTT ATTCTTGGTTTTGAGATGGAGGAAGATGTTCAACAGGTTTCGAAGTTTGTACGGGGCTTC ACAATGAGGAGTCTAGTTGGAGGAAATAGGATGTGAAGCAACAGAAAATAAGTTTTAGAG AAAGAATTTGGCCAGAACTTAACTAATCAAAGAACATTTTCTGTGTAGAGGAGCGGTGAA GCACAGAGAGCAAGGGAGCTTAAGGGGCAGATATAATAATAGTAGTGGAGGATATTTAAT ATCAGACTGAGTTTTTATTTCATACTGTAGGTAAGCAATTGGAACCACTATAGGCCCTTG TAAAGTGGCCTATGTTGGGGATGATGCCACTGTTAGAAAAAGACTTAAAAGAGTGTGTTA CCATCTGTGCATAAAATGGTTTGGAAGAGGGATGTAATTGACTGTTGAAATAACTTTCAT GAAACATGAGGGTTGTGGATAGAGAAAGGAAGAAGTAAATGTGAAAAGTAGGTTTTAATA ATACAGAAAGTAGGTTTGCCCCTAACATTTGCAAGGTTGGGGAAAAAATAAAAATACAAG CCCACATACCATATGCCTAAATATGTATAAAACATAAGCTGAACTACACCACTGTTTGAC TCATGTTTCCATCCTGAGTCCCATAGCTCACTCCCCATAGTGTGACAAAAGGGGCCATCA TCTCTCCCCAGCTAGGTCTGCTGCTGCAAGCCTGAGCTAGAGGAAGGTAGAAGCTATGTC CTTGACCCAAGACTCTTAAGTAGTAACTGGATCTACATGAACTTGGGATGGAAACTTACC CAGGCAAGCACCTAGGAGGCCAAGCCAGGAAATTTATCCTCTTCCATGATTCACTTCTTC ATTTCAGGATTTCCAGGTAGTTCTAAGCACCTCCCAAAATTACACCAAGAGTTCTTCTTC TGGTAGTAGCCAAGCATGTCTTATCATGCTGACTCTCCGGTTCACAACAACTACAAACTC TGAACTAAATATCAAAACAATTATTTGAAGGCCCTGGAGAATGACCACAGAGAATAGGGT TCTGTACTTAGAGGCAGCAGCCAAGGTCAAAACTTTAAAAAAATAATAATAATAAAACAC AAAGATAAAACAAAGTAAGAAGCTTTAAAAAAAAAAAGGAAATAGGATTTTGGATGGAAA GTATATTACAAAAATATATTGTTTTTCTTTGGAAAAGTGTTTTTAAAAAAAGAAAAAAGT AAGTGGCATTTTTGTGGGAAATTGTAAAGCTTCAATAGAGCTCTTTAACAGCATAGTACA ATATTCTACACTCCCAGGAAGAGCAAGTCAGTTGAGAAATCCCATCCACATTCACTTTAG AACCATTATTATTGCCCACCTGGCTGATTATGGATGGAGGAATATAAGGATGCAGCACAT AACCCTTCCTGGTTCAAAGCTAGGCCTCCAGCTCCACTAGGGGCTCTCAAATTCTCTTTG GTTCTCTCAGATCTTCCCACTTCTCCAGCCGTTGTTAATTTGGGAAGTCAACAGGTTACA ATCTATCAGACAGGGCTTCTTCTGTGTTCCAGGGTGACCCATTTAAAGGAAGCAATGAAG TGTTCTGGAAATGTATAGTGTTAATATCAAAGGAGACCCTGGCAACTGCCTTCTTAACCT CTGCACTAAATAGAATTTAAAATATAAAGATCCTATAATGTATAACATACACTTAAATGA AAAATAGCCCAAAGAAAGTGAGAAATATACTATAATTTAAAAAGGAAAGGGTTTCATTTG GCAAATAGCTGTAACCATTTGATTAAATCTGTTAATACCATGCAGACATTTTGCTACTTT AGTAGCAATTTATGTTTGTGGACTAAGAAAGAAAAGAATAATCAGTTCTGTTTAGTAAAC TAGAAATGACTTTGTTAGCTTTGTGAGAACATGACAATTGGTAGGAATATAAAGGAGTAA AACATTATTTAGCTGGGAATCAGATCACGTGAATTCTTATCCCAGAACTGTAACATGGAA AATAATATCTACCTACTTCTCTTTCACGAATGTAGAATATAATACAAATAAATGTAAACT CTTAAGTATTTTGTGCTTAGTATAATAGTTCCTGGCAGGGTTCCAGTTGCTAGAGATACA AAGATGAAAAGCCACAGTCCCTGTCCTCAAGTTGCTACCATCTGGATGAGCTGACAGCTA CTTCAAGAGAAAAATTATGAAGCATCATGGTTTGTGCAATGATAAGGATGTGCATAAGGG TACTGTGGCAACAGCAGGGAGGAGGAAGAGCAGCAGCCCAGACCTCTGGGAGGACAGACG CTTTCTGGATGACGTTCTGATAGTCTCAATTTCGTCAAGGTTATTTCTAAACAATTATCT CCATATGTTATCTTAAACTAAATGAAATTCTCCTTATTAATCATTTTAAATGGTTGATTA TCTAATGGTTGAAAATATCTTATGCCTTATTTTAGTACCAGATCTGTATATATGCTTAGA AAGACATGCTTTATTTCTCCTTTCCCTAAGATAGGCATATCCAGAAAATTGATAGGCATA ACCAGTGGAGGTGGTTTCAGACACACAGAAATACTGAGTAAAATGTGGACTTGCAAGACC ACATGTTGTTTAATCAGACTGAATGAAAGGCTCAATTTTCAATGCTAAGTTAATCCTGTT TTCATTAAATATAAATGTTATTTATGGAAAACAGGAGCCCTGCAGAAGCAAAAGAATATC TCTCAGGGTTACACATTTTATATTTGTTTAGCACTGATGAGTTTAAACCAAGAGGCTTCT TTGCAATTTGATTATTTGCTGCTTTCCTTGATATTGATTATTCTATCAGATTTTTCTACC AACAAAAACATATGTAAAGATTCCAATGTTATTTTACTATCAAAATGAGATGCCAGAGGA AATTACACACCACAGGTAAGTTTTTAATACAAACTAAAATCAGAAAAATCAAGTGTGGTT TGTTAATGAACTCTGGTTTACATAGAGAGGCAACAGAGAGTGGCTTTAAGGCTGACAGAC CTGGGTTCAAATCACAGCTCCTCCATTTGTTTACTTGATAGACTTTAGAAAAATCACATA ATTTAAACATCTCAGAGTCTCAGTCCCCATCCATAAAATATACAAATGCTACCCACATTT GCAAGTTATTTTCAAGTTTATTAATGTGTATAAAATGCAAGTACATATTAAACTAAGTAG TGGTTATTACCATGAGGCTCACGAAATGGTAGCTACAATGAATATTGTGACTTTGAAAGT AGCTTTGGGCCAGGTGCAGTGACTGTAATTCCAGTGCTTTGAGAGGCCAAAGTGAAAAGA TTTCTTGAGGCCAGGAGTTTGAGACCACACTGGACAACATAGCAAGACCCCATCTCTTAT AAAAAAGAAAGAAGTAAGTTTTGTTTTATTTTTAATTATTTTTTATATTAGTTTCACAAC AATATATTGGCCCTGTCAAACTTAACCACTAGTATTTTGTCTTCCTCTACTAACTCTTTC CACTTTCTTATATTGATGGACCGAGTTTATATTAATTCTACTATATAATTCATATCCTAT TGTACTGCCATTAATGTGCACTTATCTGTCTTAATTGTTTCCTTCCTCTTTAAAGACCTC AGCAGCTTAAATTTATCATTACCATATTCCTAGAGTTCTCTATTGGTAGAGATTCCCATG AAAATTAAAACTGGGAATTACAAAGGGGGAAGAGCAAGCTTAGTTTTCTAAGATTGGCTT CTTGAGCCCTGGGTAATGAAGTTATATTATACCCCATTTCCTCTGGGTTGCAGATGCTCA TTTATCCTCACCGATGATGGATGGCCTACTTTGACATTTTGCATGGATGGCTCTTGAGAA TGAAAATCATGCTTATAAAAGATTCATTGGCTCATCCTACAGTCCTAACATTGTCACCTT GACACACAGTGACAGCATTGTAATATCCATTGACCCTGTTGGTCAGCACAAAAAAGGAGA ATATGTTTCAGGATCATCTATGAGAGAAAAAGAGTTTGGGATTTCTTTTTCATAGAATGC AATAACTAATGAATTTTTAGTTCTATTTCTCTTCTGGCTTCAGGAAAGCTGGTTTTGAAA GACAGCAAAACCCTTGTGTCCTGGGAGGTTAAGAGGTCACCAACTTAAGAATCACATCCA GTTTAGAGGTGTATCTATGAGTTGTGAGGAAATTGGAACAGGGGTTCCGCAGGAAAAGGA AAAAAATATGTGAGTGCATTAGAGTGGACAATTTACTAAAGAAGATAGGATAAAAACAAA TTATGTATTAATAAATGACATCAAAAACCCATTTAAAATTAGTCACTATAAGTCACTTTT TGTTTAGTAGTCGTATTTTATATACATTTTATATTGAGTATATCCTATTTTAAAAGCAAA GTAGACTTATGAAAATAAGCATTTTGGTGGGTTTAGGAATAACTTATAATCACTTTAACC ACTTAAAAATAAAATGTGACTGACTTCAGTTTCCAGGGAAATTCTGACATAAAAATATGT TAGCCCCCTGAATTAAAGAAAAAGTATGACTGAAGCATTAATAGAATGATAATTACAGAG GCATTACCATAATCATAAGAGGAATGCCATGGTTCAGATTTAACTGCTTTGCACAAATAA AACAGTAAACTATAAAAAATGTAAAATATAAAGGAGGGCTCTGTACATTGAAATATGTGT CTTTGCACTCAACTAATTAGTTGCTACTGAATGTTTTTGCTTTGCTCAGTGGCATGTGGT ACATAAATCATTGCAATATGTTAAATGCAAATGGTTGTTAATAGAGAAACCATCTGCTCC ATGCTGGAGAGTTTGTTAAAAAGAATGTGGTGAACCTACTTTGGATAATGTTGAAAAACT CAAATGCCAAATTTCTAAAATGAGCTGCCTCTGTTAACCCCAACATTACTAATACTCCCC TGGCCTTTTAAATTCTCCAAGTTCATCACTAAAACACTCGTAACACAGTCTGTGCTGTTT TAAACAACCCCATTGGCTACTTCTAAAGGCAGAATTATCCTATAGAGGTGTCATACCACA GAGACCTACAGTGTTCTAAAATTGTGTTCAGGGATTTAGAACGACCAATAAATAATCAAA CGATCCTCTCCAGAATATCTTTGCTAACATGGATAAGACACACTCCCTATCCCTGTGCCT CCTAAAAGCTATTCCTTTGCAGCTATAGATCACTGGTAAGTTGCTGGCTGATGATGAAAT ATCATGGGTATCATCAGTGTTTGCAACCTCCACCTCCTGTAATCTACAATACTGTATTTC TTCAAAAGATCATCAGTGCAGAGGGGAGCCATGATTTCTCTCCCAACATACTTTATTAGA TGTTGTCACATAGCTTCCTAATAATGTCTGCCAGACTCACTGGTGACAGTATAAAACATG GGAAAATTAGTAATAGGAATCAGAGCCTTCATAATTTCCAATGTCACGCTCCACTTTTTG GCAAAGAAGGGAATGTTCCTTAATCCTGCCCTTTCTAATCAGCTCCTGGTCAAGGTTGTT GTCAATATATTTAAGAGCAAGCCGCCATGATGATCTACTATATTAACATCCATTGGAAGT GTGTTCACATGATGCAATACCCAAAACAGAACCTTGGCCGTGAAAGAACAACCATAGAAA TTAACTATGGATGAAGATCTTCAAGCCCACAATTTCTTTGAAGCCAAATGCAAGGTATGA TTATTGGCCTACTGCTATCTTGGCTTTCTTGACCCTACTTTTTTTTTTTTCCTTTCATTT CCCCCTTCTACTTTTGGCTTTTACAGTACCTGATTTCAGATTGTGCTTTTGGGGATTCGC CTGCAGAAGAAAAGGCTGCAGGAGAGCTCATTAGCCCAGCAGACGCTCTATCCCTGAACG AATTATACAATGAAAAGCTGCTTCTGAGGGCCACCAAAAAGAGCCAGGGCTTTGTGGAGA TGGGCAGCCCTGCAGTGCAATAGAGGCTTTTTATTTGTTAAAAAGGAATTTTGTACTAAA AACATTTCTCTTTGTTTGTTCTCGTGAAAAAAGGAGCCTCCTGAAGGCTGCGTGCATTTG ATGACTCCATTTTAAAATGAACACTTGTCAGTTTCCAAAGGGGGCTGCTGCACTTGGAAG TTACACAAAACCATTCTGAGATGGAGAGAGACTGGCACAATAATCAGACAAGCGATACCT GAAAGGCAGAGTTCTGCCTGTGAATTTGAGAAGCTGGAATACTGAATTGGATTCCAACAA TGATCCTGAGTCCTTACAAAGCCCATGTTTTAAACTTGGAGTCTAGAAAAAAAAAAATCT TACATTATCTAATTACATTAGTTTATTGAGCTATGGTATCACTTTGGTTCCCAGAACGCC ACTTTAATTTAATTTAGATTTTGTTACTTCTTCCCCTCCAAAAGGAAAACTTTACCATAG AGGCATATTTATTGTTTTTAATGCTTATGTTTGGAAACATTTACTAATTTATTTTCCCAC TTAATTACAGGGAACAGGAGGATTGATATTTACCAAAGTTTTTATGGAAAAAGAAATGAA AAGTTTCTTTGATCTAAAATTATGATCTGACTTTTTTTGTTTGTTGTTTTGTTTTGTTTT TATTTTAGGAGAGGACAGGGCTCCTAGGGAGACACGAAGAGCCAACAAAAGCCAGCTGCA TTCATCAACCTTGAGTCTTTTGTGTAGGGAAGTGCATTTGGGTCATTGCTGCCTTCTCAG CAGAATCCTATGGGGCCTCCCCAGTATACTTGCTGATATTTAGTGACACACACACCAGCA GGGAGGGGATTCAAACACATTCCATCTGTTGGTGTTTTAATTTTTTTCAAGTCTACTTGA TGAAGTGTTTGTCAGCAAACTTGTCATTCTGTTGTATTTGTGAGGTTTGGGCCCTCTTCT TGGGCCCAAAGATATCTCTGAGATACAAAACAGAATTTCATAACCCTCCCTTAATACCTT TTTTATACTGTCAGTGTCCTCAATTCTAAAACATTTTTCTCACTTTTATTCTGAAACTCT TTTGGGTCATAAAGTTCAAGTTGTCTAGTTGGCTGACAACAGTGTTTATTTATCCTCAAA GATAAGGTTAATTTTTTAAACCTTGCCTTCTCCTTTACAGTGTAGCAATCTGCTTTAAAA CAGCAGGAAAAAAAGTTGATTTGTGAATAAAACATCTAGTTTTCTTTAAAACAGATGAAA ACTATGTAGTTTATTTTTACTATCAGGAAAAGCATAGCATTCAAACACTGATATCCCTGG AGTAGTTCCAAAATGTTGCTTGTAATATTTTTGTCTTTCTAAGAAGGATAAGACCCAATA ATTCCAAGAGAGACTAGGGATCACGTCGTCTTGTAGGTCTGACCATGAAAATCTCTCCAA ATGTTTTGAGTTTGTCTCATTTATTTACCTGGGAATTTAAATGCAGAGTTCCAGAGCTAT ACGGAAAATCTGGGTAAAATCAGATAACTGATCTCTACCCTGCTTGATGACAGAATTAGT TATCAAAATAGAGAAGAGCTAACATTCGAAACATTATAAGCCGGAACTACTTACTGTTAG CTAATACTCAGAATAACTGACCCTTATTATTCTTTGTGTGAATCCAAAGAGCCCAAAGGG TTATTTTCAAAGTTCTGTGGATTATGCTGGAAGGCAATGTGCTCAGCAGGTCACTAGACA GGTGTGAGCCGCTGTGGCACAGAAGTTACAAACATAGCAGCAAGGGAGAGCGGATTACTT TGGCTTTCTCCTTTGAAATGGCATTTTTCTGGGATAGGAACTTCAGATGGCATTTCATAT TATTCATGACGGCAACCTTCAGTCCAGCACCATTGTTCTAAAAAACCCACCTGCAGGCTG ATAACTGGCCCTCATCTCAAACAGTCTGAATGTCACCCACTGTATTTTACGTGCAGCCTT TGCAGTACCTTAGAAATTCTTTTACCTCAACTAATCCCCATAAGAAAAGTGTACTGCCTG CCCTAGATTTTCACTGTTTTCTCTTTTTCTTTAAAAACTTTCTGATTGGAAAGATTTTCA TTCCTAGGTTATGTATGTGACATGGTGAGCAATACCCTCTTCTCATTTCCAGACTGAGGG TATATATAGTCTTCTCAGAATTGAAAGTGTTCATTAGTTCACTTGGCATAGATTGTATAA CTTGTGAATCTATTTTCTGAGAAGGGATTTCCTTCAGGCCCTAATGTATCAGAAAAGGTA CAGTTACATCAACCAGCAACACACAAAAAAGGCACACCTGATAAGCCTCGATTTGAGTTG GGGTCTGGTGTCTCCCTGCCTATGTGGCTGATGTGTTGCAGTCTGATTTGCCCAGGCATT GCAATTTCTATAGATTTCAAAAAAGGAAAAATGTAGGAGACTAAGAAATACTGAACTACA GCCAACAAGAAATGACTGAAGTTTTTCTCCATCAGTAATACAGCTCTGGAAGAAGATTGA TCCCTGATCAATTTGGCACTATGAGGAAACTGCATTTCTTTGGCTCTGGGTATAGATTTA CTACAGTCAGCTGGCCAGAGGCAAAGTGGTGTTTGAGTGAGCCATTCTGATACCCTTTAA GACTGCAGGCTGGAGAAAAAGACCATTCATTTGATGGCAACCCAGATGCAGAGTGGGAAC TTACCAGATAACTGGATTTCAGGTAGTGGCATGGACATGACCCATGCCCCTTTCTAGGAT GGCAGCTTAACTACATAGGTTCTGATGGCTGTTCTGGATTTAAAATACTTTTCTCTCAAG GTGCACACACAAATCTGCTATATATTTAGATTTTTTTGGCAAGTTTTAAAAAACTCCTCA GAGATGTCAAAACAAGTGAAAAATTTATATCCAAGATAAAATGTTCAGTAGCTAGTTTAA AAAGGAACTTTGATCAAACTGAGGGGACCAGAATAGCATTTGGAGGTTTATTGCAAGGCA CCCCCTACTTAACACATTCTTTCAAGATTGCTTAAAGATGGCTAATCTTGCCCCTATAAC AGCCAGGACTTTCTTATTTTGTATATGCATTTGTGAAGAATGTGAACATAGTAGGAATTC AAAAAACAGCAGCTGCACCTTAGTTCTTTCACCTCTGCCATGATCTCTTTTCTATCCTAA AAAAAAAAAAAAAAAAAAAAAAATGAAAAATCCTTTTTGTGGGGACATGTGCTGACCCAG GAAAACAGTGGTGGCAGAAGCAGCTACAGCATGTTTTAGGGGTGGAAGGAAGAGGAAGAG GTAGGGAATAAAGAACAAGGCAAAGCAAGCAGGAGGAGCAGACTTCTAGAGTGAGACAAA AATGGTCACAGTAAGGCTTCCTATCACTTGATGGGCATCTTTGTCGTCACACAGACTGGA TTCAAATCCATCTCTCCATCATTTACCATCTCTGTAACTTGGGTGATGACTTCTCTCTGA GCAATAGTTTCCACGTCAGTAAAGTGAGAATAATGACTGGCCTCAGGCTGGGCATGGTGG CTCACACCTGTAATCCTAGCACTTTGGAAGATCAAGGTGGGAGGACTGTTTGAGGCCAGA AGTTCAAGATCAGATAGGCAATATAATGAGACCCCCGTATCTAGAAAACATTAGAAAAAT TAGCTGGGCATGGTGGTGGGTGCCTGTAGCACCAGCTACTTGGGAGGCTGAGGCAGGACG ATCTTTTGAGTCTAGGTGATTGAGGCCGCAGTGAGCCGAGATTGCTCCACTGCATTCCAA TTTGGTCAACAGAGCGAGATCCTATCTCTTAAAAACAAACAACAAAACAAAACAAAACTG GCCTCATGAGATTGTTGAGAGAATTAGCATATAGTGTGCTGCACTTGGTGTCTAGTACAT ACATGGTAAGAATTGTTATTTGTCATGATTTATCTGTGTTAGTCCATTCTCACACTGCTA TGAAGAAATACCCGAGACTGGGTAATTTATAAAGGAAAGAGATTTAATCGACTCACAGTT CTGCATTGCTGGGGAGGCCTCAGGACACTTACAATCATGGCAGAAAGCAAAGGAGAAGCA GGCACCTTCTTCACAGGGTGGCAGGACGGAGTGAGTGCCAGCAGGGGAAATGCCAGATAC TTATAAAATCATCAGATCTCGTGAGAACTCCCTCACTATCATGAAAACAGAATGGGGAAA ATTAGCCCCATGATCCAATTACTTCCACTTGGTCCCACCCTTGACACGTGGTGATCATGA GGATTACAATTTGAGGTGAGATTTGGGTGGGGACACAGAGCCAAACCATATCATATCTGT GGTTCTGACATCCTTGCCTTCTGACTGCCTATCTTCTCTGTCCCCATATTGGTACCCAGT TTTTTTGTTTGCTTTTTTTGTTTGCTTTTATTATTATTATTATTATTATTATTATTTGAG ATAGAGTCTCACTCTGTTGTCCAGGCTGGAGTGCAGTGGCATGGTCTTGGCTCACTGTGA ACTCCACCTCCTGGGTTCAAGCAATTATTCTGCCTCAACCTCCTGAGTAGCTGGGACAAC AGGTGTGCACCACGACACCTGGCTGATTTTTGTATTTTTAGAAGAGACGGCGTTTTGCCA TGTTGGCCAGGATGGTCTCGAACTCCTGACTTCAAGTGATATGCTCACCTCGGCCTCCCT AAATGCTAGGATTACAGGCTTGAGCCACTGTGCCTGTCCCTGGTACTCTTCTTAATCACT ATGTTAATACCTCTATTTTACCAGCTTCCATATTAAGCCATTTTCCTTAAATTATTTCAT TTTTATCAAGGGCTGTCCACTGTTGTGCCTCAGCCACTGTCAGATGCACCAGCCTCAGCT CTCAGACCTCCCTCCCACCTCCAAACATTGTCTTGTTCTGAATTTCATTGTCCCCCTGAT GACAATGGGTAATGAACATTTTAGTAAATTAATTCAAATAAACTGATTTCTGCTATGGTG TCTAGGATAAAATAGAAAATTTCATATCCAAGTTGAACCCTGCCTCTCCAAGAGACTTAG GATAATGCTGATAATGCTGTGTGCCTTGCACCTAGTAAGTGCACAATAAATCTTGGCTTC TTTTATTACCATAATTATTGTTGATAGGAATATTATTATACTGTTCTCTGTGCTTTTACT TATGCCTCTCTCAACTCTATTTTCCACTCTACAGTCAAAGTTCTCTTTTCCAAACTTAAA TCTACTACTTTTGTGCTTAATATCCTCCCATGGCTTTTAAATGCATTTCAGATAACATCC AAACTCTACCTCCTGATTCTAGTGCCCTCCATAGTGAGCCCTTGCCTCTCTCTGACTTCC TCTGGGATTACTACTCCATTGGTCCCTCAGCTCTAGCCACAGAGCCTTCTTCTGTTCCTC AGTTGCCAAGCTTGTTCCTGCTTCAGGACCTCTTCATGAGCTTCTAATTTCTCTACCTGG AATGCTGTTTGCCTGACATTTCATGGATTCCTTCGCATTAATCAGATATCATACCAAAAG CCACTTCTGAGAATCATTTTCTCTCCAACAGCAACCCCACCCTGATTATATTACCCTGTT GTTGTTGTTCGTAGCACTGAGCTCTGTATAAAATAATAATCTATTTTTTAATTTATTTTA AATTTTTTTTCTATGCATATATGTAATTTAAGTTATATGCATAAAATCCTTTTTAATGAA ACATACAAAGAATGTATGTAGAATAGATCTAGGTTAGGGAGCTGAATAACAAAATTACCC ACCTGTGAACCCACCACAGAATTTGAGAAATAGAATATTAGCAATATTGTTTAAATCCCT TATGTATTTCTCCCAAGTGACAATACCATGCTGCTACATGTCCCTGACTTTTTGACCATC CACACTCACATCTAGGATAACCATTATCTTGCATTATTTTTTCTCATTCTTTTGCTTTGC TCTGTAGTTTTAGCACATGGATACTTATCCCTAAACAATATATTGTTTAGGTTAGTTTTA AGTGTCGTAGTGTATGCCTTCTTCTGAGACTTGCTTTTCTAGCCTAATATTATGCTTCTG AGAATCATAAATATTGATGAAATAGTATTCCATTGTGTGACTATACCACAGTTTATCTAT ACTCCTGTCGATGGATATTTGGGTTGTTTTAAACTGCTGCTCTTATAGATATCCTTGTTA AGAAATTTTTGGTACATGTGTGCAAAAAGTATCTAGGGAAATAAATACCTTGGAAGGGAT AGGTAAGAAGCACATATTCAGCATTATAAAATAACCCCTACTTTTCTTCCAAAGTGTTGT ACTAATTTATATTTTCAACAGCAGGTCTAAAAATTGTACTTTCTCTCTACGAGTTGGTAT TTTCAAACTTATTAATTTTTTTCAGCCTCATGAATGTAATATAATAAGTTGTGGTTCTGA TTAATAATCTCATTACTGATGAAGATAGAAGCTCTAAATGTCTATCATTCTTGTTTCTTA TATTGGGAAATATCTTTCCCTGTATTTTGCCCATTTTTAATGAGAGAATTTATCTTTCAT TTTAATTGATCCATAGAAATATATAATCAGGATTCTAATTCTTCATCAGTTTTATCTTCC TTTCTCCAATTCATGGCTTGAATTTTCATTCTCTTTATGGTGACTTTTGATGAATAGATG TTCATAATTTGTAATTAATCAAATTTATCCATAGTTGTCTTTATGATGATTATGTTTTTG TGTTTTACTTAAGAAATTAAATCTTTATTCAACTACCATATGATCCAGCAATCCTACTTC TGTGTATATATCAAAAGGAATTAAAATCAGTGTCTCAAAGAGATATCTGCACTCCCTTGT TCACTGCAGCATTACTCACAATTGCAAAGATGTGGAATCACCCTAAATGTTCATTGACAG ATGAATGGATAAGGAAAGTGTAATGCATATATACAATGTGATGTTATTCAGCCTTAAAAA AAGAAGAAAATTCTGTCATTTGTGACAACATTGATGAGCCTGGAGAACATTATGCTAAGA AATATAAGCCAGGCACAGAAAGACAATGCTGCAGGATCTCACTTATATGTGGAATCTAAA GAAGTCTAACAAATTGAAGCAGAGAGTAGAATGATGGTTGCCAGGGGATGGGAGGTGGAG AAAGTGGGAAAATTCTTGTCAAAAAGTGCAAAGTTTCAGTTATGCAGGTTGAATAAGTTT TGGAGAGCTAATGTACAGCATGGTGACTATAGTTAGTAATATTGTAGACCTAAAATTTGC TAAGAATATAGATCTTAAATGTTCTCCCCACACACACAGAGGTAACTATGTGAGGTTATG GTTGTGTTAATCAGCTTGATTGTGAAACACTTCACAGTGTTTATACATGTCAAATTATCA CTTAGTAGTATTTAAATATACACAATTTTTGTCTGTTAATTATACCTTAATAAATCTATA AAAATGCAATCTTTGTCTTCCCCAAATCACAGAGCTACTCTTTCTTAGCTTCTTCAAAAT GTTTTAGGATTTTGCCACTCACAATAAAGTCCATGACCCACCTGGAGATCAATTTTATAT ATGGCTGTTTTAGTCAGTTTGCTCACTGCTATAAAGAAATACCTGAAACTGGATAATTTA TAAAGAAAAGATGTTCAATTGACTCACAGTTCTGCAGGCTATACAGGAAGCATGGCAGCA GCTGCTTCTGGGGAGGCCTCAGAGAGCTTTTACTCATGGTGGAAGGTAAAGCAGGAACAG TCATCTTATCTGGCAGGAGCAAGACCAAGAAAGATGGGGGCAGTGCTACATACTTTTAAA GAATCAGATCTCATAAGAACTCACCTGTACCAAGGGGATAATCTGCCCCCATGATCCAAT CACTTCCCACCAGGCCCCACCTCCAGCATTGGTTATTACAATTCAACATGAGATTTGGGC AGGGACACAGACCCAAAACAATATCATTCTGCCCCTGGCCCTTCCCAAATCTCATGTCCT TCTCACATTGCAGTATATAATCATGCCTTCCCAGCAGTCCCCCAAAGTCTTAACTCATTC CAGCATTAACTCAAAAGTCTGAAGTCCAAAGTCTCATCTGAGATAAGGCAAGTTCCTTCC ACCTATCAGTCTGTAAAATCAAAAACAAGTTAGTTACCTCCAAGGTACAATTAGGATACA AGCATTGGGTAAACATTCTCCTTCCAAAAGGGAGAAACCAGCCAAAAGAAAGGGGCTACA GGCCCCGTGCAAGTCCAAAACCCAACATGGTAGTCATTAAACCTTAAAGCTTCAAAATAA TCTCCTTTGACTCCATGTTTCACATCCAGGGCACAGTGGTGCAAGGGGTGGGCTCCCAAA GCCATGGGCAGCTCCATCTTTGTGGCTTTGCAGGGTTCAGCCCCTGTGGCTGCTTTCATG GGTTGGCGTTGAGTGCTTGTGGCTTTTCCTGTTGATGGGAGCAAGCTGTTGGTGTATCTA CAGTTATGGGCTCTGGAGTACAGTGGCCCTCTTCTCACAGACCCACTAGGCAGTGCTCCA ATGGGGACTCTGTGTGTGGGCTCCAGCCCCACATTTCCCCTCTGCACTACCTTAGTAGAG GTTCTTCATGAGGGCTTTGCTTCTGCAGCAGGCTTCTGCCTGGACATTCAGGCTTTTCCA TATATCCTCTGAAATCTAGGCTTTTCCTGGTGACAGGTGCAAGCTGTTGGTGTATCTACA ATTATGGTCTCTGGAAGACAATGGCCCTCTTCTGACAGACCCACTAGACAATGCTCAAAT GGGGACTCTGAGTGGAGGCTCCAGCCCCACATTTCCCCTCTGTGATAAGGCAAGTCCCTT CCACCTATGAGTCTGTAAAATCAAAAACAAGTTAGTTACCTCCAAGGTACAATTGGGTAA ACATTCTCCTTCCAAAAGGGAGAAATCAGCCAAAAGAAAGGGGCTACAGGCCCCCTGCAA GTCCAAAACCCAACATAGTAGTCATTAAATCTTAAAGCTTCAAAATAAGCTTTAAGGTGT GGATCAGCTTAAAGGCGGGCAGCTCACGAGGTCAGGAGTTCTTACACACTCTCTTTGTAA TATGCCTGTTCCTGCTCTGCATTTTTAAATAAGTTCTGTGCACCTGCAGGCTTAACACCA CATGGAAACCACCAAGGCTTATGGTTTGCACCCTCTGGAGCAGTGGTCCTAGCTGTAGGT GGGCCCCTTTGAGCCACAACTGGAGCTGGAGCAGCCAGCATGTGAGGAACAGTGGGCCAA GGCTGTGCAAGGTGGTGGGGCACTGGGCCTGGCCCAGGAAACCATTTTTTCCTCCTAGGT TTTTGGGCCTCAGATGAGGGGGCCTGCCATGAAAGTCTCTGAAATGCCTTCAAGGCTGTT CCCCCATTGTCTTGGATATTAACATTTGCATAAGTAAATTAACATTTTTCTTATGCAAAT TTCTGTAGCCTGCTTGATCCTCTCCTAAAAATGGGCTTTTCTTTTCTACCACATGGCCAG GCTGCAAAGTTTCCATACTTTTACACTCTGCTTCCCTTTCAAATATGTGTTCCAGTTTCA AGCCATTTCTTTGCCCACACATATCAGCCAAAACTGTTAGAAACAGCCATGTCAAATTTT GAATGCTTTGCTGCTTAGAAATTTATTTTGCCAGATACCCTAAATCTTCATTCTCAAGTT CAAAGTTCCACAGATCCCTAGGGCAGGGCACAACGCAGTCAACATTTTTGCTAACACATA ACAAAGGTGACCTTTACTCCTGTTCCCAATGACTTCCTAATTTCCATCCGAGACCTCCTC AGCCTAGACTTCATTGTCCATATCACTATTCACATTTTTGTCACAACAGCTTAGCAAATC TAGAAAGTTTGGAAGTTCCAAACTTTCCCTCATCTTCCTGTCTTCTTCTGAGCACTCCAC ACTCCTCCAGCCTCTGCCAGTTACCCAATTCCAAAGCTGCTTCCACATTTTCAGATATTT TTATGGCAATGCCCCACTCCTGAATACCAATTTTTGTGTTAGTTTATTCTTGCACTGCTA CAAAGAAATACCTGAAACTGGGTACTTCATAAAGAAAAGAGATTTAACTGGCTTATGTTT CCACAGGCTGTACAGGAAGCATGGTAGCATCTGCTTCTGGGGAGGCCTCAGGTTGCTTTT ACTCATGGCAGAAGGCAAAACAGAGCAGATGTCTTACATGGAAAGAGCAGTACCAATGGG TAGAGAGGTGCCATGCACTTTTAAACAACCAGATCTTATGAGAAGTCACTCACTATCATG AAACCAACACCAAGGGGAAATCAACCCCAATGATCCAATCACCTCCCACAAGGCACCACC TCCAACACTGGGGATTACAATTTGACATGAGATTTTGGTGGAGACACAGACCCAAACCAT GTCAATGACCCTGAAGTGAGATCCAGTTTATTTTTTTCTACTTGGATAACTGATTGTTCC AGCACCATTTATTGAATAGTTGTAGAGATATAGAATTAAATTGGCCAGGCATGGTGGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGCGGGCAGATCATGAGGTCAAGAGTTC AAGACCAGCCTGGCCAATATGGTGACACCCTGTCTCTACTAAAAATACAAAAATTAGCCG AGCGTGGTGGCAGGCACCTGTAGTCCTAGCTACTCAGGAGGCAGAGGCAGAAGAATCGCT TGAACCCGGGAGGTGGAGCCTGCAGTGAGCCACGATTGTGCCACTGCACTCCAGCCTGGA CGACAAACTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAGAATTAAATCACCC CAAGTATTATGATATTAATTAAACCATTAAACACCAGTCAGTATGGGTGGAAACCTGTAG CGCTCAGCTGCATCCATGGGTAAAACCCTATGCTCAGCTACATGGGGATCATCAAAATGC CACTTGCATTCATTTCTGCTGAAGCTCAATAAGTTGCATGACAGGGACCCTCTCCCATCC CCTTTTGGTCCTCACCAATACAGTCTTTCAAAACTTAGTCTACCCCTAGCATCACTGAAA ATTCCCACTTGTGGCCTGCACGCTTCCTCATCCGCTTCCACTGGACACTCTCAGAGAGCC CTTTTGTGGGTGTGCTCTGTCTCTCATCCAGGGAATGCCTATTGCCTGAGTGAGTAATAA ACACTTCAGTTTTTTATGATAGCAAACTTTAGTGTGATGGGTTTGACATTATATACCTTA AAAGACAAGGGAGCAGTGTGCCCAGCTGTTAGTATCCTAAAAATAATTCACCCTTTCCTG TTGATAAGCAATGCTACTTCTGTCTTATATTGAGTTTCTCTCTACATGAAACTCTTATCA TTGAATTTTTCATTTTAGTGAACAGATATTTTATTTCTAGAATTGTGTTTGGTTAGTTTT CTTTTTTTCTTTTAAACCTTCCTGATCATTTTTGATAGTCTCTGATTCCTCACTTGTGCT TTTAATTTTCTCTTTATTTCTTAAGGCTATCAAACATGGTTATTTTGATCTGATTGTTCA ACTTTTCAAAGTCTTTACAGGTCTAGTCTTTTTTTTTTTAACTTTTTTATTGTTTTTTTT AATTGACATCATTCTTTTTACTTTTTCCACTGATTCTCACATAAGGCAGTAGTTTTCTGC TAGCTTTGTGAGTTTTTTTAATTCTTAGCTTATAATTGATGGTAATTTATCTTTCCCAAT TCTTTAAATAATAAAGCAAATTTATGTTTTCTTCTTTACGTTACTTAGGGGTAATGGGGA CTGGATCTATTTAAAGTTATAATTCACAGATTGCAGTCTTAAGGAACATACCAATAGAGT ATATTCAAACTTCAGAGCACATAGTGTAGTAATCAGAAACCGAGATATTTGTTCATTTTT AACCACTACTTAGAGCCAAGCCCAAACAAATAAGTTTCCTTGCCAATTGTCTCAACAACA TTTACAGGAAGTGTGGATGTCTCTATGAAATGTGCATATATAAACAGACACACACTAATT TGCCCTTTCTCATGAGGCCTTAACCTTTCTTGGGTTTCCTTCTTTATTTAGGGTTATCTT TGATGCAATGGCATCAGGTCTTTTCACAATACAAGTCCAACCACCGCCACCCTCAAACTC TAGGCCACAGAGATTCGGTAATCCATGGCTTCAGTAATGCTCTGGTTTTATTGTTTATTT CTGACCTCAGTGGATTTTTCTACATTGTTTTACACAGTCTCAAAAGTGTTCATAAATTAT TGTGTCCTAAAAAGATTTTTGTGTATTCCAGACCACCGTCGTGGCAGAAACAAAAGTCTT CATATTTTGGGCTGTTTTACCTTCATGAAAATGTATTCACTATGAAAGGGATTTAGTCTG TTCTTCTCACCTTTGTCACCTCAGTGCCTGGAAAGTGTCTCCATCCTGGTTATACTTAGG GTTGTATCCAGTGATTATGCACATCTGGCATAAGGCCTCACATAGACATATTTTAAAAGC TCTTTAAGAAATTTTAATCCGATGCTAAGATTAAAATGATATTGACCTAGAACATACCTG GTAGAAAGTATATTCTCAAAAATATTTATTGAATGAATGAATAAATTTATTTATTTGTTT ATTTAGAGACAGAGTCTTGCTCTGTCACCCAGCCTGGAGTGCAGTGGCACAATCTCAGCT GACTGCAACCTCCACCTCCCAGGTTCAAGTGATTGTTGTGCCTCAGCCTCCCGAGTAGCT GCAATTACAGGCGCCCACCACCACACCTGGCTAATTTTTGTATTCTTAGTAGAGACAGGG TTTTTCCACATTGGCCAGGCTGGTGTCGAACTCCTGGCCTCAAGTGATCTGCTTGCTTCG GCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCAGCCAGTCCTGTTGAATG AATTAACCAATTTATAAGAATGATTTTTTTTTAAGGAAGAATTTGGCTATTTTCTGAAGG GAGTCAAGTCATTAGAAGAAACGTATTGTATCCTTTGGGTATAGGAATTAAAGACCAATC TGGTGGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCCAAGGCTGGTAGATCACTT GAGTTCAGGAGTTTGAGACCAACCTGGACAACATGGCAAAACACTGTCTCTAAAAAATAT ATAAAAGTTAGCCGGGCATGTTGGCGCATACCTGTAATCCTAGCTACTCGGGAGGTTGAG GCATGAGGATCTCCTGAACCCAGGAGGTGGAGGTTGCAGCAAGTGGGGATCATGCCACTG CACTCCAGCCTGGGCAACAAGGTGAGACTCTGTCTCAAAAATAAAAGACCAATCTGATGA TGGGGAGAATTTTAACAAGTCTGTCTCCATCTGGGCCTAATCAGCAGTGCCTAACCAGAC AACACAAATCACCAAATATAATTTTTAAATGCATTCACTGCTAGGCCCCACCCCAGTCAG AATTGGCCCTGACAATTGTGTCCATGGATTCTTTCCCTAGGTTACAGAGGACTAACTTAT GCCCTATAGTATATGAGAGTACTATTTGAAAGAAATTATTTTCTGCTGACCTGATCCTCA TTGAGCCATGATCTCAATTAAAAAAAATTCCTAAATTTATACTTAACTGGGCCAGAAAAG ATGAGCAGGCATGCAGTGAGCATGAGAAAGGGAAGAAAAGCTAAACATGATTCATTCAGG ATTATAACATATTTTCTAGATACTTTGATTGTAATACCTCCTTGTCAAAGTCTTGGACCC CAAAATCTCCATAAACATATGAGAGCTCAGCTTTTAATTTTAACTACTTCATTTCTTCCA CAGACATTTCATAGTTCCTTAAAAACTTTAGCTAATTTCATTCTTTACTTGGCTGATCTG ATAGAAATAGTTGAGAAATGGCCAGAAATCCTGAATCACCAAGTTAACATTGGAAGAAAG AGGACAGCTTGATTTTAAAAGCTAACAAAGAACAAAGGGAACTGGAAAAAAATTATTTTT TGACATAAAATTGTAAATATTTTTTTTTCAGTGATATTTAACAATTCGTTTTTCACAATG ACAGCTGTAAATTATTCATAACAGGCTATCTGGTCCTTAACTTTCCAGTTATCTGTGATT ATAATGGTGAGTTGATCTGAAATGAAGGAAAATATTGATTAGAAACATTTGAAATATAGA TGAAGTTCTTTAGTTAGAATATTAAAGTTGCACTTGGTTTCATATATCTAAGGAACATTT GAAACTGTAACAGTGGAATTTATAGCATTATATACTACTCTTCTATGTAAGTCAAATCGT TTCTTTTAAATTTCTGACCACTCAAATAATAGATCATTCCATTCGAATACATGGTTAAAA TTTTGAAAGATATCAAATTAAAAATGAGCTTTTATTGTGACTCTAAACACTGTGAGAAAG TGTTTACATGTCCTAAGAATGCATATATAACAATATGCACAACCTGAAAGTAAATACCTA AGGTATGAATTTTTTTAATCTTTGTGGGGAAAAATGCAATTGAGAGAAAATATTACACTC TGGACTAAGAAATATTAAGTGCTACCTCTACTTGAGTTATTTTAAAAATTTAGTTCTTCA AGCCTTATTGAAGAAGATGATACTCTCAAGTTGAGCACTGGAAAATAGATGGGCATGAGG AGATAGTACTTAATTTTTTTTTTTTTTTGACATCTATGACTAGAATTAATCAACAGCAAA TGGCCACTTGCACATAGATTTGGTCACGAGTGGGGGTTTCCTGTTCTGGATGAGTCTGTC TAATGTAAACTTTTTCTTTACAATCAATTCATTTGTTGCATTCTAGTGTTGATCTAGCCC ACTGAAAATCTGGTCATCTTTTTCCAAACTAATACAGAGCACTGACCTATGGGGGAGAAA AGCCTAAATTTTAGTGTATCTGTTTTGAAAGTAAGGAATTCTAAAGAGGACCTTACGATG ATAATCAAATCATTCCAGGAAAAAAAAAAAGGCAGAGAGTTTAACAACATCTACAAGCTG CTGTTGCTTAAAAACACAGTATTTGAACTGCAATTTGAGCATATTTTTACCCTTCAGACA TTACAAACATGCCATAACACCCTGCTGTGAGGACAGCTTTGGTGCCCCAGAAGTAAAAGA GTTTAGCTGTGATTAAAGGATTGAAGTCTGTGCCTTGAACTGACAGATTAGTTTATGCTA GGTTTTCTCTGTTAATTCTAGACTTGACAGCTCCACTGTAAATTAATCTAAATTATGGCC AACTGCTACAAGGCTGATCATTGTCTCACAAAAAAATATAAAGTTCTATTGAAAATGCGG ACGTCTCTATCACCAAATGTTACTCCAATTTGCTAGAAATCTGAACAAGGCAACTTAAAA CACACACACAGGAAATTGCAGCTCCTAGATGCCAGTAGAGCTATAGAGATTTGGACACAC AAACTGAGCTGTTGGGGAGAACGGGTCTGACTTCTGTGGTCACTGATGTGTGAGCCTCAG TGTTTGTCTTTAGCAGCTCATGACAATGTAATTACATCCTGCGTGCCCAATTTTTCTCAT AAATGAAGTTGATAAATATAAACTACAGTTTATGATTGTGAATCACAGCCTGAAGCAATA CAGCATGGTCATTGATTGCAGAGAAATATAAATAGGAGATGATAATAGATTGACTGAATC TGAACCCTATCACAGACCAGTTAAGATATCAGAGAATCAGAGAATGGCTTAAGAGAAGCC TTAGTTTCCCAGGAAGAGAAGAGAAAACAGGTCTGGTGGGCAAACAAAGGCTTTATAGCT TCATTAACCTATTCATACCTATAGGATGATCATTTCTCTGGAAATTGCCCCTATCTGAGA CTTGATTGAGAGTAGGCATCAGAAGTGAAGGGTGACTTTTTCTATTTTCTGTCTGTCCTT GGCAAGCTCCCCCACCCCCAACACATTTGCATCACTGATTCTATGTTCTTAAATTTGGAG CTTCCTGTTTCTGTGATTAGAAAACCTACAGATAGGTTTACATTTGCATTCACTGTTCAT ATCATTAGGGAGCTGAACAGACAGTATTGAGTGCATACACCGTGCTAATTCACCTTTACA TCTGAAGGAAAAAATACTAAGTGTGATAAGATGAAAAAAAAGGAAAAGAGAGAAGTGGAA ATACATATTTATAGAAAACAGTATTTTCTCCAAAACTATCACGAGATAGTCACTGCTATT TATTGTGTAACTTATGTAAACCCAAAACAGTTGGGCCCAATCTGGTCCCCAGATATATCT TATTTGGTCGACACAACATTTTACTTATTTTTTATTTGCATACCTCTTAATCAAGCCTAA ACTGTTCACACATGGTTGCTGCTCCCGCCACACCCTGTTGTCTTATACAGGGTCTGCTTA CCTGCCTGACAACCGACCAACCCTTTGGTCTATAGCACTCAAACATATTGATTAGAAAAA TTGATTTTTTTTAGGAAAATGTTTAGTGGGCATTATATACCAGGTACTGAACTTGACACA CCAAAACAATAAATATAATTTCAGGCAGTGATATATACCATGAAGAAAAATGAATCAGGG TAAGGGAAAGAGAATAAGAAGACAGCCACTTTAGGAAGAGGTGATCTGAGAGGTCAGAAT ATCAGAACAAAAGTTAAAGGATGTGAAAGAGTGGGCCACGGAAATATCTGTGGAAGAACA TTCCAAAAAGAGAAACAGTGAGTGTAAAGACCCTGAAGAGAAATAGAAAGTACAGTATGG AATACTCAAGGTGGAAAGTGATAGAAATTAAGGTAGGAGAGATGAGCAAATGCCAAATTG TTTAGGTCCTATAGGCAACAGGAAGCCACTGGAAGATTTTCAGCAAGGAAATCAAGTAAT ATAATTTATATGATAATGAATGGATAGTCTCTAATTCATGGGTAGTACATAAATAATTTA TTTGAATTCTGAAAAGTATTTGCAAAGTCAAGTAATGCCTGTGAAATTTTATCTGCATTA TCAGTCTGCTTAGCAAATCAATATATTAGAAAGCATTTAAGTAGCAACTAATATGTGCAC ATCCTATGCTAAGCCCTGTTTAGGATGTAAAGATCACTTAATATATGGTCCTTGACTCAT AGCCGAGAGGCTACTTTCTAACATCTAGTCACCAGTCACTGAGTATCTCTCGTCCATGCC TCCAGAATACATGTTACATATTTCTTCCCATGATTACTAGAAAGACTTAAGAAACTTAGT TTTGTTATTGATTTGTATACATGACACATAAATCTGCTTCTCGTGTAACTGCTATCTCAC TTCTTTAACTCTATAAATTTCATTGTTTTAAAGAAGAATCAGTTCTTATATTGCAATATG GAAGTACATAGCTCCAAAAAAAAGGCAAAAGATCTTTGAAATGGGTTTGAAAAAATATAT ATAATATATATAGTATTATATATTTCTTATATTATATATTATATATTTCTTATATAAAAT ATAATATATATTATATTATATATAATTATGTATAAAATAAATATATATAAATTATATATA AAATAAACATATAAATTATTATATAAAATATATGTTATGTAAGAACTATATAATATATAA TTTTTATATAAAAATATATAACATAATATATAACATATATAATCATTATATAATGAATAT ATACATTATATAACATATATATATATACATATATATATATATATATTTTTTTTTTTTTTT GAGACACAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCAGCTCACT GCAACCTCTGCCTCCTGGGTCAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGAT TGCAGGCATGCACCACTATGCCCAGCTAATTTTGTATTTTTAGTAGACATGAGGTTTCAG CACGTTGGTCAGGCTGGTCTCAAACTCCTGATCTCAAGTGATCCACCCGCCTCGGCCTCC CAAAGTGCTGGGATTACAGGTGTGAGCCACTGCACCCAGCCAGAAAAAAGCAAATATTTT AATCACTGCCAGTACCTCCTCATCCTGTTGAAAGCTGATGTCATTTTTGACACTCGGGAA ATGACTTCTTTATGGAAGAAATGATAAACTAGTCTGCATCCTGCTGCAATAATCTGAAGA AAGAGTGTTTGCTATTTCAATTCTGAGGATCACTTCATAATTGTAACATCAAATTAGCAT CTTGGCTTATGCTACACTATTTTGTAGAATCTTAGAGCGTGGCTGACAGGGTCCATGGAG TACTCAGCTGGAACAGACTGATTTAAATATGGCAGAGACAACAACAGGGGAAGGGAGAGC CCTGAACAACATTGCAGAAAGCGTGAAGCTCATCCCATATCCAGCACTCCCTCGTCTCAT GCTCTTGTACCACCATCACAATCTCCTTGGGCATCCAAAGAGCACCCATCCCTGAAACCA TCCATCAGAATTACCCCAACCTCTACCCATTTTCCTCAGAACTCTCTCTCTGATCAATTT TCTTAAGTCTGTGTGCCATGATATTTTCACCTCAATAAAATAATTGCTATTTAAAAGAGA CGGTTACACCTTGCCCAAAGGAATAACTAAAATGGTGGAAATTCTGGATGCACTAGCTGG CAGCTTAGGAGAGTTATGGAGAAGAGGCTTTTTATTTCCTTTGTAATACTACCACTTGAT GTCTAATGTGAGGTATGCTAGATACCTGTGGTTGTTGGTTACATGTTATCCTACTGCTTT AATTACTGGAAAGCTAAGTGTTCACTAGTTAATTTTCACTGTGGCCTCCACTATGGGGTT GCCGGATCTAAGTAGGAACATGAATTAGTCTGTGCATTATTCCAGCACAAATGAAGCCAA AGCTGAACAGGTGCATGATGTAGTGCAGTGAAAACACCATGAGCTTTGGAGTCTGAAGAC CTAGATGTGTGCTCAGTGTCCACTGCTTGATGAAGCAGAGGTGTGGGCAGGTCCCTAAAC CTCTGAGACTCTTGCATCAGCTGTAAAATCCAGAGTTGCTGTGAAACTGAAACACGGCAT ATATGTTAAAACACTTTGTAAACTGTAAAGCACAAGGCAAATGATGCTATTTTCAATTTA AGCAAAAATAGAATAAGGGCAGATGAAGATTTCAAGACCTTTCAGATTTTTTTAAAAGTT TCCCTACCCTTCTTAACAATCTGTTTTTATTTTGGCTGATTACTTGAGGATGAGCTCAGG AGAATATTCTGAGCAAATGTTTGAGTTTGGTCTTAGTGCCTCGCCCTTTCCCTCCCTTCT GTTTCATGGCTTTTCCATGGCTGGCTTTTATCATACAGAAGGCTGGCTGACTGAATTTCT TAGGAACATTTTTATATCTTGTCTAATGGATGGTCAGGGTTTCATATTGCTGCTTCTTTT TAAAAGTTAATCAAAGAATTACAGGCAGGTTTTTTCCTTGTGTTGTAAATATGAATTAGT CTAATTATAGTTTTCAAAAGAAAGCATTTTCACACCTGAATTTCATGAACATATGATGGA GAAATGACAGGGCTTATTCATTGGATGGTTTTCTGAAGGAAAAAAGCCCCACTGCAAATA CAAATAAAACAGTGTCTTGCTGTATTCCTAGGGAGGGAGTATAGAATTGTGTAGTCTCTG TGCCAGAAAGCCACATGGAGTATATCATTGCAAAGTCTCATAGTCATGAGGAAACTGGGG GGTCATCCAGTCCAATTCAGTCATCATTTAGAATACACAGGAAACATGATTTAATCTGCA ATATAACTGCGTTCAACATCATGCCTAATTTCATCTCCTTATCTGAACCATAGTTTGCAC TTAATAAATGTTAGTTAAGTAAAATTAATAATTATCCCACTATTATTTCCCCCAATAAAA AAACCTGCTAATAATATCAGTCTCTTTTCTGGTTAATTCTATTCACTTCATGCTTTTATT TGCTTTTTCCCTTTGTGGAATGTGGATCCTCTCTTGCCAGTTATATAAAGATTGCTTCTC CTTCAGACGTTAGCTCAAGGCTCATCTCCACCAACAGGCACCATTTCATATTGATCACTT GCTTTCATCTTATCTGAACTCAATTCAATTTAACATTTAATCGTTTCAACATGCACATGT ATATTTCCTCAAATATTATATACAATACTTTCATTATTAAATAAGATGTAGTATGACATA ATTGCTACCTATCTTACATTGTTCACTATTGTTTTGATCAGTTATTTTGTGTTGTTGGTC TAGGTAACATTTGGGGGAAAAAGAACTGTCTCTTTTTATTTTCTGATGCTGCACAGTGCC CAGTGGAGAGAGGAGCATAGGATAGATGTGAAATATTTTGCTTGACTGACTAAGAAGAAT GTATAAGTATTTCTTGGGTAAACTGCTTACACTTATTTTATTGAAAATATGTCATAATGA TATTAATAATTTAAGTCACTTTACCCTAATACAATTATTTCTATTTTTGCAAATTATCTT CCAAACCTTTTTCACACCATACGTATTTTATATAATTGTTTTCAGAATATACTTACTATT TTGTATTCGGAATTTTAATTTGTATTTACCATAATCATTTCAGTAATTTTACATAATTCT CGTGGCTATCATTGTTAACTGCATAATGAGGTACAGCACAATATTCCCTTGTTTATTAAG CTATTCACTTATTATTAAACTTTTAGCTTTTCCCCATTTATTTCTTTCATAGGTTACACT GCAGTGAAGACCTTCATAATAAAGGTTTTTTGTTGTTGTTTTACTTGAATTATTTCATTC AGACATATTCTAGGAGTGAACTGACTTGGTTAAAAGACTCATTGAATTTTCTCACTACAT TTTACATATAGTTTCACAAAGTGCTTCTGCAACCATTTACGACGTGCTCAGAAGGGCCTG GGGTACTCTCACATGAGCTCTTAGTGACCTGATCAAAACTGCACCCCTTGGTTTCACACA TAAGAAAGCATCTCCATCATTTTTTTCCTCCTAACATGTATTGAGCAATTGTTCTGTGCC AGGCAACATACTAAGTGCTTTGAATGCTTATCTACTCTGAATCAATTATTCTACCTTTAC AGATAAGAGTAGTTCCAAGTGCGAAATTACCTGCTTAAAGTCAATTGTGTAGTAAAATAC AGAACCAAGAGTCCCAATCCGTGTCTATCTCATATGCACATAATTGTTGATCTACCTTTT GTCTCCCAGTCCTCATTCATTATGTAAAAAAGTACTTCCCAAAGTATAGCACTTGTAACA CTGATGGGAAACAAAATAATTTATATGATGCACAGTCATGTATTCATTTTAATGAGTATA TTGAAACAATAACATTTTGGATACATTAAATTAAATACCTTGTTAAAATTAATTTCACCT GTTACTTTTTTTGATGTGGCTAGTTAGAAAATTTAAACTTACATATGGGGCCTTGTATCC AAAGCTCACATTACAGCTATATTACAAAGTGTTGACTTAAAAGACAGTTGAGATCCAATA TATGGTTTTGGACTATGGAGCAGATTTCTTTCCTAGAAGACTTCATTCAAAATGGTCAAA ATCAACTCTGAGATATTGTCTTTTTTCACACCATAACTCCATAACTCCAGCCTGTATTAG GAACTGTCCAAAAAAGTATTGATGTTCCCTACCAAAAAAAGATAACCAAAGGGTCACCAA TGTGGTGAATGATTTACTGATGGTACGCATTAATCTTTCTTGGCACTCCAGGGCCCATAA GAAACAACTGGATTCCAGCCCCATTTTTAAGAAGTTAAAGGATAATAAAAAAAATTGTAC ACATGAATATATATATTCATTTGCATATAGGTAAGCCAATATAATTTTTATATATGCAAT TTTACAGTCGCTTACCATATGTGATGTAATGATGTCTATAAATATAAAAATTCAAATTCA GCCATAATACAGAATAGACAGTATCTTCAATGAAACATAATCATATTTTTGCATATTTTT TCTATATGCCACTTGGCATGAGATATGATTTGTAACAACTACTTAACATAATCCCTCAGG ATCTGAATTCATAAGAATTTAAAATCTGCTTTAAAGGTCTGAAACTACATTGAGTTTGTT TTGCTTGGGGGAGGGCAGATTTTAAGCATACCACTGTTATGCTCAAGCATTATTTTATTT TATGTTCATTCAAAGCTATATTAAACAGTATGGAATTAACCTCTTTTGTTTCTCCAGCAG CAGTAAACAATTCCACAGAAACTCAATTTTCTTTCAGTTCATAAATGTACTATATTCCCC ACTGTGTCAAATTACCTTCTCTTCCTTTCCAGTAAGCTGATGACAGATAAAGATTCTGCT ACCCATGTCTGTTTCATGCAACAATAGCAGTTGACGCAGATCTGTAACAGCTCACCTGGG CAGTTCTGTTAGTGTGTGTGTGTGGTGGGGGAACATAGCAGAGAGTTAAGTAATATTTTT AATGGTATTGTAACCATGTCCACTCAGAAGGTAATTTAATCTCCACAATGTTAGACCTCC CACACAACAAATTGTTCCCTTTCAGTGTGGCACAGTAGAGAGAAAAGAGCACGACACCAG CTGGCAGTTGCTGCTATGGAATACTACCTACAAATATAGATCGGAAGTTGTGGGTCATCA CTCATATCTCAGAAGGACTTTTTTAGGATGGCTACTGAACAGATGTAAGGGCACTTTTAA TTAAATATAGACCCAAAAAATCTGTCTCAAAATAAAGTTTGTTGTGACACATTCTCTCCA GAGACCTGGAAATTCGTAGCTAAAATTAACTTTAGAACAAAAGGGTTTAGAGTCAAGGAT GATGTTCCAAAGGGCTACAGAATGCCAGCATGTTGGGTTATAGCTCTGTAGACAAAAACT ATTTCTGTAAAGCTCTCTGTATATGTGTTTATATTTAAAGGTACTCGAAAGGAGAAAGTC AGACTTCAAATTCTTCCCAAGTTATTAGCATATAAGCTACTAGGACAAAATGAAATCTTC CACATTTTATTTCTAGACTGAAATGATGCAGAATTAACTCATCTATTAGGGATGTAGGAT GTTCTCTGCTTTTTATGTTTTCTTCTGAAAAATGTATAAGAAATTATATGAAATACTTCT AAAATATCCATTTCAAGATGTTTCAGTTCATTTCGTTCACAAAAGCTGCAGACCTTTAAA TTTCTGGTCATTTAAAATCCTATTTTAGTATTCCAAGAAGCCTGGGTTTCTCAGTCAGAG TTACTGTACAAAATCTTGATTAAATATTTATAAATTTCTTAAAATGTATATTACTTGCTT GATCTATTGAATAAGCATATATTCATTAGTCATTTTGTACAAAGTGCTGCTACAAAGGAA CAATGTCTTTTATCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCTCTAGCAC ACTATGGGTGCATAATAAATGTTTAATGACATCAAGCCATGTGATAAATCAGTACTGTCC TACAGATATAACAGGCAAAGGGGCTGAATCCTGGACTTAGGCTTGGCCATTTTAAACCCA TGCCTGCCCCAAAGAAGAAGTACAGATCTTAATGTTTGCCTGAAATTGATTTTTTTTTAA ATACAAGACCCTGAGAAATATAGATAGGAATTAGAAACATGCAGATTTGAAACTCCTCGA TGAAGGGCACTGAATCTTCTGAATGTCTGACACCAGCATGCTTGGTTCATGTCAAATAAG TAGTAAATAATTCTGGAGTGAATTATTATCATTATGGCCTAAAAAACTTCATTTGTAACT AAGATCAGATTTACCCTCAGGAGAAAGTTTTCCTGTGTGACTCTTAAATCCTGGAATACC TTTATGCCTGTGGATCCCTGTTGCATCTTGGCAAGCCTGGAATGTCACAACAATTTTTCT CATTTGTAAACAGGCAATTTTACCACAAAATAAATAAATAAATAAATACATGGCAAATAC GTGAGCCATCCAAATTTCCCCTAGTCCTTAGTCTACTGTAGTTACTCTGTGCTAAAATCT TTATTTTTTATTTTTTCTGTCTGTTTGTTTGGTTTTGTTTCTGTTTTTTTGTTTTTTGGG GGTATTTTTTTGTTGACATGGAGTCTCACTCTGTTGCCAGGCTGGAGTGCAGTGGTGCGA TCTCAGCTCACTGCAGCCTCCGCCTCCCTGGTTCAAGCGATTCTCCCACCTCAGCCTCCT GAGTAGCTGTGACTACATGCACACACCACTATGCCCAGCTAATTTTTGTAATTTTTAGTA GAGACGGGGTTTCACCATGCTGGCCAGGGGATCAGGATGGTCTGACCTCAACCCGCCTGC CTCGGCCTCCCAAAGTGCTGGGATTACAGTCATGAGCCACCGTGCCCGGCCTAAAAACTT TAAACAAGGATGGCTGAAACATCGATCCAACACATAATAGGAACCCCTTTCTTCTATCTT CATGTCCCCATTATCTCCAGGATTCTTAGAGGATTTTCTTACATCCTTATTACCTCTGGT TCCAATGTCTTAGGTCTCCTGTCTTCCTTCTGTTTCTCCCCTCTTCCTTCTTTTCCTTCT CCCCCAACATGAATCTAAATGTGTGCAATAAAGATGATTCTCAGGTGTGCAAAAATACCA CATTTGTTTATTTTCTTTACCTAAAAAAAAAAAACATTGGTGGCAGAATTATTTAGTACA AGTTTCTCATTTCACCTTGCATAATGATCTTGTGTGGTAAGCACTGTTGCTTTCCTCATT TTACAGATAGGGAAACTGAGAAGGAGAGAAGTTGACTAACTTATGTAAAGTTTCACAGCC AGTACCTAAAGTGCTAGAAGTTGAACTTGACTTCTAAGTTGACTGTGATTCACTGCCTCC TTCATTAGAGCCACCATGAAGTAACATACTAACAGTGAGCACTCACTGAGTACTGCCTAT GTAACAGCATTCTTCTGAGTCCTTTAAGTGCATTATTTCACTTACTCTTCATATCAGGAA CATGAGACTTGCACTGTTGTTATCCCAATGTGACAGATAAAGAAACTGAGTCTCAAGGGG ACTCAGTTGTTTATAATCAGACACCTAGTAAATAATGGAGTCAGGATTCCATTCCAGGCA GTCCAACACTAAGACCTTGTCTTTATTTTGTAAACAGTTTTATTGAAATGTAATTGACAT ACAATAAACTGCACATATTTGAAATGTACAATTTGATATGTTTTGACTTATGTATACATC CGTGAAGCCATCACCACAAGCTAAGTAGTGAACATATCCATTATGCCCAGAAGTTTCTTC GTGCCCCAGATCAACTTTGGTTTTACAGATTAGTTTGCATATTCTAGAGTTTTATATAAA TGGAATTATATAATATGACTCTTTTATCACTTCTTTTATTCAACATAATTATTTTGAGAT TCATTCATGTCATATTTCATTCCACTTTATTGATGTGTATTATTCCATTATTTATCTATT CACCTATTGATGGACACTTGGGTTGTGACCAGTTTTTGGCTATTACAAGTAATGCTGTTA TGAACATTCATGTACAAATGTTTTATGGGCATATATTTTCTTTGAGGTAAATACCCAGTA GTAGAATGGCCGAATCATATGGTAAACATAAGTTTAACTCTTTAAGAAACTGTCAAACTG TTATCTGACTTAGTTATAATACGTTACATTCGCACTCACAGTGTATGAGAGTTCCAGTTC CTCCACATCCTTCACCAAATTTGGTGAGGGTCAGTCTTTTTAATTTTAGACACTTTAGTA GGTGTGTAATGGTATCTCATTGGGATTTTAATTGGCACTTTACTAATAACTAATTGCATT GAACATCTTTCATTTGCTTATTTGCCATATATCTTTCTTGGTGAAGTGTCAGTTCAAAAC TTTTGCTCATTTTAAAAATTGGGCTGATTATTTTCCTATTATTGAGTTCAGAAAGGTCTT TATGTATTCTGGATGCATATTCTTTGTCACATGTATGCTTTGCAAATATTTTATTTCAAT ATGTGGATCTCCCAATTTATCTTTTCCTTCTCTTAACATTGTCTTTTGAAGAGTAGAAGT TGATCTAGGTGTGTTCTTTATGGATCATCCTGTTGGTGCCACATCTAAGAAACCTTTTCC TAATCTAAGGTCACCAAGACTTTCTGCTATGTTTTCTTGTAAAAATGTACAGTTTTAGGT TTCATATTTAAGCCTATGATCAGTTTTGAATTAATTTTTGTAAGCGATGAAGGTATGAAT AGTTCAGTTATTATATGAATATCTAATTGTTTTAACAGCATTTATGGAAAAGACTATCAT TTTTCCACTGAAGTGTCTTTGCATTTTTGTCAAAAATCAGTTGTGTATATATGCGTGGCC TATTTCTGGATGCTATATTCCGTTCTCCAATCTATCTTTATACCAGTATCACACTGTTTT AATTACTGTAGCTTTATAAGTCTTGAAATCAGGTAGTGTTAATCTTTCAGCTTTGTTCTT TGTAAAAATTGTTCTGGCTATTCTAAGCCCTTTACATTTCCATGTAAATTTTAGAATGAG CTTGTCAATTTCTTAAAAAAAAAAAAAAAAAAGCTGCTGAGCTTTTCTCCAAAGGAGAGG ATTACTTGAGAGTGCGTTGAATCCATTGATAAGTTTAGGGAGAATTGTCATTTTTTTTTG AAAATTTTTTTCAATTTTTGTCTCCATAGGTTTTAGGGGAACAGGTGGTACTTGGTTACA TGAGTAAGTTCTTTAGTGGTGATTTGTGAGATTTTGGTGCACCCCTCACCCAAGCAGTAT ATATACACTGAACCCAATTTGTAGTCTTTTATCCCTCACCCCCCTTTCATACTTTCCACC GAGTCCCCAAAGTCCATTGTATCATTCTTAGGCCTTTCCATCCTCTAGCTTAGCTCCCAC TTATGACTGAGAACACAAAATATTTGGTTTTCCATTCCTGAGTCACTTCACTTAGAATAA TAGTCTCCAATCCCATCCAGTTTGCTGCTAATGCCATTAATTCATTCCTTTTTACAATAT TGAGTCTTCTGGCCCATGGACAAGGTATATTTCTTCAATTATTTAGATTTTCTTTAATTT GCCTCAGCAATTTTATTTATTTCTGTATAGGTTTTGCACATATTTTGTCAAATTTAATCG TAAGTATTTTATTTTTATGCTAGTATAAATGCTATTGGCTTTTATTATAATTTTCAACAG TTTGTTACCACTATTTAGAAATACAATTGATTTTTGTATATTGATCTTATATACTGCAAC CTTGCTAAATTGACTTATTATTTCTAATAGCTTATTTTAAATTCTTTCAGTTTTTTACAC AGACAGTCAGAAGTGGTGAGAATGAGCATCTTTTCTTGCTCCTTACATTAAAAAGAAAGC ATTCTGTCTTTGACCATTAAGTGAAATGTTAAATATAGGTGTTCGTTTATCATTCTGAGG AAGTTTCCTTCCATGCCTAGTTTCCTGAGAGTTGTTATCAGAAATGGATGTTGAGTTTTG CTAAATGTTTTTTGTGTGTCTTTTGAGCTGATCTTGTGGTTTTTCTTTCTTAGTTTGTTA ATATGGTGAATTACATTAATTCATTGTTGAATGTTAAAACAACCCTGCATTTCTGGAATA TACACACTTTACTTAGTCATCATGTATTATCCTTTTTATATATTGTTGAATTCATTTTGC TAAATTTTTGTTTAGAATTTTTACATCTATGTTTATAAGGGTTATTGGCCTATACATGAT AGATTCTATAGCTAGTAAAAGGAAAATTAGGAAATATTGTGAACAATTTTATGCCTTTAA ACTTGACAACTTAGATAAAATAGACAAGATTTTTTGAAAGATACAAACTACCAAATCTTA CTCAAAAAGAAACAGACAACTCAAAAAGCCTCATATTTATTAAATAAATTGAACTTGTAG TTAGACATCTTCCCACAGAGAAAAGTCCCAAGGCCAAATTCACTAGAATCAGTAGTGAAT TCTACGAAACATTTAAGAAAGAAATACCAATGCTACACAAACTCAGCCAGAAAACTGAAG AGGAGGGAATACTTTCTAAATCATTGTCTGATGCAAGTAACAGGCTGGTACCAAAACAAG ACAAGATCTTTACAAGACAAGCTGAGTATTACTTATCCAAAAAGCTTAGGACCAGAAGAG TTTCAGATTTTGGATTTTTTTTATTTTGAAATATTTGCATTATATACTTAATGGTTCAGC ATCCCTAATATGAAATCCAAAATACTCCAATGAGTATTTCCTATGAGTGTCCTGTCAGCC CTCAAAAACATTTTAGACTTTGAAGCATTTCAGATTTGAGGTGCTCAACTTGTAGTGTAT CACCTCTCTCATTCCTTATGTAGATAATTTGTGTCTTCTTTTTTCTCAGATCAGTTTAGC TAGAGATTCAACTTAATTTATCTTCTCTAAAAACTATCTTTTGGTTTCATTGATTTTTTT ATTATGTTTATTTTTTCTATTTCATTGGTTTCTGCTTTGGTATTCATTAAGCATACTTTG GGCTTAATTTGCTCTTCTTAATATGCTTTTCGTTTTCTAGTTTCTTAAGATGGAAGGTGA GGAAATTGATTTGAGGCTTTCTTCTTCTGTAATAATATTGGAATTTAGTGCTATAAATTT CCTCCCTAAGTACTGTTTTAGTACTGTTTCAAAAATTTTGATTTATTTTGTCAGTTCAAA AATCTCAAAAGGGAAACTTTTTGAGATTTAATTTGACCTGTGGTTTATTTAGATGTATAT ATTTATTTACCTAATATTTGGGGATGTTTCAGACATTTTTCTGTTATGAATTTTCAGTGT AGTTTCATTATAATCAGAGAACATACATTGTATAACTTCATTTTAAATTTATTTCAACTT ATTTTATGGCTTAGTAAATGCTCTGTATATACATGAAAAGAATGCATAATCTGATGTTTT GGGGTGGAATGTTTTAAAAATGCCAATAAGATCAAGTTGGTGGATAGTGTTGTCAAGTCT ACTATAAACTTGCAAATTTTCTATCTACTTGTTCTATCAATTACTGAGAAAGGACTATGG AAACACCTCGCCATCATTTTTTTTTATTTGTCCTTCAATCAATTTTGCTTAATTCAATTT AAAGTTCTGCTTCAGGAAGAATAAACGATTAGAATTATTTTGTTCTTTTCATCAGTTAAA TCCTTATTATAATTAAATAACCTACATTAACTCTGGCAATAGTCTTTGCTCTGAACCCTG CTTAGTCTGATATTGATATATCATTCCAGCTTCCTTCGGGTTAGTGTTAGCATGATCTAT TTTTCTGCACCCTTTTCGTGGGCAGCATATAACTCGTCTTGTTTTTGTTTAAATATCTAT CCTAATTATAGTGTTTAGATTATTTATACTTAATGTAATTATTGATATCTTTAGACTTAA AGGTAATATCTTGCTATTTATTTTCTACTTGTCCCATTCTTATTGTTCCCTTTTCCTCTT TTTCTGCATTTGTTGGGATTAATGGAATTTTTTAAATGATTCCTTTATATCTCCTTTGTT GGCTTACTAGTCATTTTTCATTTTTTTAACTTAGAATTGCTTTAGAGTATATAATATATA ACTATAATTTAACACAGTCTAAATTCAGGTGATATCATACCAGTTCAGATGAAATATAAC AACCTTACAATAGTACTTCCATTTCTCCCCTCTCAGACTTTATGATTTTGTTTTCACATG TTTTACAGATATATATATATCTAATATACCTCACAATATATCATTTTTGTTTTAACAATT ATCTTTCAAATAACAGATAAAAACTTACATATTTACTCACATAGCTACCATTTCTTGTTC TCTTCATTCCTTTGTGTCTAAATGCAGAATTCCGTATGTTATCCTTTTTTTTTTTTTTTT CCTAAAGGACTTCCTTTAACATTTCTTGCAGCACATGTCTGCTGGAAATGAATTCTTTCA GCTTTTGTATGTCTGAAAATGTCTTTATTCAGCCTTCTTTTTTATTTTTTATTTATTTAT TTTTTTTCAAGAGACAGGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCA TAGCTCACTACAGCCTCAACATCCTGGGTTCAAGCAATCCTCATGACTCAGCCTCTCAAG TAGCCGAGACTCCAGGCGTGTGCCACAACATCTGGCTATTTTTTAAATTATTTTTTGTAA AGACAGGGTCTTGCTTTTTTGCTCAGGCAGGTCTCAAACACCTGGCTTCAAGAAATCCTC CTGCCTCGGCCTCTGAGAGTATTGGGATTACATGCATGAGCCACTACACTCAGCCACAGA CTTCTATTTTGAAAGATATTTTACTGGGTAGAGAGTCCTAGATTGACGTGTTTTCTGTTT TTCTTTTATTACTTGGAAGATTTTACTCTACTGTCTTCTCACTTGGATTGTTTTCAAAAA GAAATCTGTGTGTAACATGTCCTTTATTCTTCTGTTGCTTTCAAGATAGTCTGTATTGCT CGTTTGGGGCATGTTTGTTTAAGATGTGCTTGGTGTAATTTTATTTATTTATTTTTATTC TTGAGGTTCATGACACTCCTTGGATTTGGTAAAGTCAGAAAAGTTTTGGTAATTATTTAT TCAAATATTTATTTGGCCCACCCATCTCTCTCTCTTCTCCTTTGACTATTCCAGTTACAC ATGTCTTAGGTGACTTTACATTGGCATGCAATTCACTGAAGCTTTTTGCATTTTTAAAAA TTTTTTTTATCTTCTCTATGTTTCATTTTAAACCATTTCTATTGCTGTGTCTTTCACTTC ACTAATCATTTCTTCTAATTTCATTCAGTGTATCTTTTTTTACAGAAATGTACTTTTTGG CTCTAGAAGTTCAATTTGGGTCTTTTAAAAATATATATCTATATATTCTATTACTTTAGT TAATGTTTGAACATATAGAATACAATTATAATAATTGTATATAACTGTTTTAATGTCCTG TCTGCTAATTCCAATATATGTGTCAGTTTGGAGTTGATTTCAGTTGATTATTTGTGTCAT TTTTCTGCTCCTTTGCATGACTGGCAATCTTTGATTCTATAATAGGTATTGTGAATTTTA TCTGGTTGAGTGTTGAGCCTTTTTGTATTTTTATGAATATTCTTTAGGGTTTTTTTTTCT GTGATTTATTAAGTTATTTGGAAACTGTTAGTCCTTTCGGATCTTGCTTTTCTGACTCGT TCACAGTAGTCTAGGGTTAATTATTCCTCATTATTGAAGCAAGACTTTCCTGATTATCTA CTCAATGCCCTGTGAATTAGAGATTTTCTAGTCTGACTAGTGAGCACCGGCACTATTCCT AGCCTTGTGTGAATACTGGGTGCTTTTCTCTAATACTTTTGGAGGTTTTTTCCCTGCCTT CATGTAGTTTCTTCATACACATACACTAACAAGTACTCTGCTAAATCGTTCAGGGGGACC ATGTACAGATCTTCAGTGTTCTTTGTGCAATTCTTTTCTCTCCAGTACTTAGCCTTGACT CTAGCATCCTCAGTCCCCTGAACTCACCTCAACTCCTTTGATCCGGGAGTCTAGTAGCTC AGCCTGCGTTCCTCCTTTCTACACTCTGGCAAGCTAAGGCAGTCATTGGACTCATCTCAT TTGTTTTCTGCCTCTCAGAGGCAATTGTCCCTCCTTACCTGATGTCTTAAAAACGTTTCG TATATTTTGTTTTGACTTGTTGTTGCTGTTGTTTCAGGTGGGAGGTTAAATACAGGTCTT GTTACTCCAACTTGGTTGTAAGTAGAAGTTCTTCTGGAATCCTTCTTCTTAATTAATATT TTTTCCAGTGATTACTGACATGATCTACAGGGTACTATTGATCAGCTATTTTTAAATGGC AGATTCATTGGCTAAAGTGCCCTTATTGGATATGAAAGTTATATATTATTATGTTTTAGT CAAGAATGTTGACTTATCTTTTGATTCTGACCCAAAAAGGGATTACAACCCACAATGAAA CCCACTTTAGTGCCTCCACCTTCAGGTCATAGATTGATCATTTGACTGATAATTGATAAT AAGCAGGATTTTTAGCTACCCCAAGAGGAAGTAAATATGAAGTTCACCATGTCAGACATC AGACCAGCTCAGAATCATAGTCTTCTTGGTATTCACACTTTTTTGCTCTTTTAACTGTTT TTCCTGTGCTTTAAATTCTTGTGCCTAACCACCTCATTCTTTCTGTTTACCTCTTCCTCA TTTTGGAGAAAGACAGAGAGTAGGTGACTAGTCAGGACATTTAATTATTAATCAGTTGCT TCTAGCTCATATCTGCCTAGAAAACAATAATAGTAATGATAGTAATTTGCCAACATTTAT TGAGCACTTATATTGTGTTAGGAACTCCTATAAGCACTTTACTCTTATTGACTTATTTAA TCATCAAAACATATAATAATATTGCTATTGTAGGCTGGGCGCGGTGGCTCACGCCTGTAA TCCCAGCACTTTGGGAGGCAGAGGTGGGCGGATCATGAGGTCAGGAGATCGAGACCACAG TGAAACCCCGTCTCTACTAAAAATACAAGAAATTAGCTGGGCGCGGTGGCGGGCGCCTGT AGTCCCAGCTACTCGGGAGGCTGAGGCATGGGAATGGCGTGAACCCGGGAGGCGGAGCTT ACAGTGAGCCGAGGTCGCGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCGTCT CAAAACAAAACAAAAAAAAAAACAAAAAAAAAAAATTTGCTATTGTATTTCCATTTTACA GATTGAGAAGCAGAGGCATTAAGAAAATTGTCCAGTGTTGTATACCCAGTTAAAAAGGCA AAGGATCCCAATCAGGAAACCCTGTGAGGAGCCTGAGATCCTACCCACTCTGCCGTGCCA CCTTATGCCCAGGCTCCCTCAACTTTAGAATTTACACTGGCCCTGAATTTTGTTTTGTTT CTGTTTTTTTGTTTTCCTTGAGTTTCTTACATGCTTTTCTCTGACTTTTAATTTGTATGA CATGGAAATTTTTAACCTAATTGCTGACATAGTATCTCGAGTGAACCTTACTGGATAATT TCTTGGCTTTCTTGGTCCCAGCTTCCAGTCTTCTTTTGCTGCCCCCCCAGCCACCAGCCC CAGCACATGCAAGTGTCCCGTCTTCCCCTACTGTTTATGTTCACAGCTCTGTTCCTTTGT AACTATCTGAATAACGCCTCTTCTCAAATGAAGATCACTGCCTCTGCCTACTTATTCATT GACTCAGCAGCAGAGCTTCATTTAGAGTAACATAGGAAAAGCAGGGAGTTGCAGGTCTGC AAAGGGGGAGATTAAAGTGCCCTGAGCCTGATATGTGTGGCTTCAGGGTCCCCCTGACTC CTCTTCCTGGCTTACATGGGGCCAGTTGAGCTGCTTGTCACATATCTGTTTCCCCCAGTT TTGGACACATACTTCCTTAAAACAAGGTTGTTGAATTTAACAACACTTGATGGAAGCTTT GGGGAGCACTGAATACTAAACTGAGAGTAAGTGACTAGTTTTAAGGCCTCACATTGAACC TCCCAGGAGGCATCATGCAGTAGTGATGTGGCCAGGAACGGAGGATTATCTCAGTCACCA CCACACCTCCAAGCTCCCCACTGCCTGGCTCCAGAGAAAGAGAAGAGAACTCCTTTATCC CTCTAAAGCCCACCTAATTTCCTGCCTGAGGATAATTGTCTGAGAAGATTCTATTTCTTT AAGGGAAATTCTCACATCTACCCAGAGAATGCAGCCAGACCTCCTGGCCCAGGAGAAAAA CAATGGCTCTGTTCAACCAGTACATTTAAGTCTGTCGAATCCACCATAACTTCACCTTTG AGACAGCAAAATTCAGTCCTGGTTGTGTGCACAAGCTCAGTCTGGTTCCTCTTCACAGCA TTTTCTCCAGTGAGAGGATAAGAGATCAGAGCACCACACTCCTCCTTGTGCCCTGCACTC TTCTTATTTCCTATGAGCAAGTGCTTGGGCAAAAAGATGCATGTATCTACCAAGGACAAG TCAGCATTTTCAGGAATAAGGCAGCATACATTGCAATTTACTGGGGAATCTCCCTAGACG TGTGGATGTGCAAACGAGGCATCAGACTTACGTCACTAACCAGAAAGCTTACCATCTCAA GCTGAAGTCCCTGCACTTGGCTATTTCACAGGATCAGGGCATTCCCAACAAGAGTGGATA GGTACTTGCATTATATATTGCATAAAGGAAAAGTTCACCAAAGTGATTTTCAGAACTAAG GTAGACTTTGCCACACAGATCTAATCCAATGGTGATGTTGCTGGCAGAACTGCCAATCGG TTTCATTAACACTAAAGTACATTTTTACCAAATAAATGTCCCTATTTAATGTAAGTGCTT ATATTTAGAAAAGAAATGAGAAGTGGAATTATTTTACGTGCTTGCAATGTAGAAACCGAA GCTCAGAGAAATTAGACAATAGGTCTAAACCAACCCTGTGCTTCCCCAAGTGAAATAACA CCAGGTTCATGAGGAACTCCTGGGTCAGCAGCAGAAGCACTCCTTCTCCCAGCCTCAGCA CATTGCCTATGACCCTTGAGGATGTTTCTGATGAGGTGAAAGACTGATCGCATAGCCAGG GAAGAAGATATATCCAGAGACCTGGCCAGGTGATTGCTTTCGGCAGGGAAAGAGCCCTTT CTAAACAAGTGACCGGAATGTAAAAATCAGGGTCAGACACTTCAAATCAAATCATCCACA AATGCAGAAACCAAGGATGGATACACATTGGTCTTGGTTAAAAGTAGAGACTCAAATCTG GGGTACTTGGGGATGGGGGAACAGCCTTGGAATGCAGAGTCACAGCCACGGGAGCTGGGA ATGAGTTTGTTAAACCTGACTCACCAATGATGGAGGGCAGAGCTGGGTATGGAGCCAATG TCAGGCTCAGGAGAAGAATGTCGAGGAAGGAGAAAAGCCCAAGGTACAGGTTCACAGGTC AGGACAGACTACAGACAGAGAGGCTGGTCTGGCATAGCTGAGAGTGTCTTGACGGACTTA AATCCCTAGAGCCACCCTTGGAAGCACCTGTTCCTCCTGGCTCAGTCTGGCGGGTTGTGG GGCCAGTCTGCCTGCTTCCTGGCAGGGTCCTGACACCAATCAATGGTGACTGCACAGTCC CCCCACACATGAAACAGAGGGCACTCTGTTAGGCAGATTCACTGTCAACCTTGTATCTTA CTCTTTGTCATAAAGCTCTTGTGTTTACCACTGCATTAAATATAACCCTGCAATAGAAAA ATCCTCATTTTCATGCTTGAAATACATTATCTAATGGCATATCTATTTGACTTTTACTAC ATGCCTTTCATTCCTCTGAGGTAATTGACCTTTACTTTGCTACCCTGTGGATTAAAAGGC TACCACACACTCTGCATTTGATATTTCCAGTCCTGCAGGAGAGGCAATTTCCATTTGCTT TTGTTGCAAGGCTGCTCTTCAGGCGGGTCCTCAAATGAAGGGAAACCTCAAGGTCTGGAA CTGCATCGTGGCAGTTATTGTCAGCATCATGTGGTTTTTATTTTAAAAAGCACATGTCGC TTCATTTCTATGGTCATCTCTACGGAATTGTAAAGACCTATAAGACTTCCAGAACCTTCC ACCTTCGTTTCAGATGCTATATCCTCACTCTCTGAGGATCAGGGATCAACAGTGGCCTTC AGATTTGATTCAAGCACCTGAAAGTTTAAAATTGTGTCCAAACTACACAATTCATGAGAG ATAAAAACATGAATGGTATTAGTCATATCCTAAGCTGCCAGCCATATAGATCCAGAAACC TTTCATGTGATAATTTAGCAATACTGTTACAAAGAACTCTGCAAGTCAGGAATTTGGAGA TCTTGGCTTTCTCTAGTGCCCTATCAGCCCTCCTTCCCACAACCAAAATAATAACAAGAA TAATGAAGGTGGTAATAATGATAGCAAGCACTATGTGTCAGGTACTATTTTTTAAATACT TCAAAGATAATAATTTGTTATTCTTAACAACCTAATAATGTAGGTACTGTTAAAATCCAG TTTTACAGATGAGGAAATTAAGATACATAAAAGTTAAGCAACCTGCTAGCAGGTGGTAAA GCAAGTGGAATTCAAATTGGAGCATTTTGGACTTGAGATAGAAGACCAGGATACAAGAGA AGGAAAGAACATCAATAAAGATGCTATTCTCAGAACTATCTCCCTGGGGTGGGAAAAAAT ACTGGAGTATTTATCCTCAAACATCTGTTTCTTTGAGAGTTGCTCCTGGGAAGTTAAATC ACCTCTGGCCTGTTCAACTTGACTGGCCAAGCATCAAGCATGTTAAGGCAAAAGGCAGAG ACTATGAAGCTGACTGTTGGGAGAACTGTCTGCAGTGACCTTCAGGGGAGGCCACAGGAA AATTTGAAAGGCAATGATGCTACCCACTTTTTATTTTTTCAAGCACAAAACCCTAATTAA TCTCTCTTTTTTTTCCATCAAATGATTTTTGATAACCTGTTAAAGCCATAGCAGAAATTT TTGGCAAATAAAGCAAGGCAAAGTGATCTCCATTTTCAAACACTTAAAAGATGAAAGTTG CCTTACTTTGTTTAAAGTATTGCTAATAGGACTTGGGGGAGATGGGAGAAGGAGGTGTGT GGAGAAGAGCTAAGTCATTATGTTATCACTTTAAAACCAGTTTGGCTTTATATTCTGTTA CACATATACTCCCTAGGGATGATTTTTTTCTTTATCTGTAAAATAGGGATAGTGATACTT TCTTGTATCTCTCTCATAAAGCTGCTGTATAAATGAAGTAAAACACCATTACACTGTTAG GAAAATGTATTCTTATGAAGGCATGTTTAAACATGAAGTAGTTCAATAGTGCTAGCTAAT TTACTATTGTTATTATTATTTCTCTGATCCTGGTTTTCATATTTCCACAGCGAGGAGATA GAATTAGATAATTTTTTCCAGCAAGTGTTTATTAAGAGCTTACTGCACACCAGGCGCCAT GGAAGGCCTTGCTCAGGACCTGGGGATTCAGCCCTGCCTGTCCCCTGACCATACCCTGAC CATCCCCTGCTGGTCCCTTACCCTCAAGAAGCTCATAGTCCTGGTTCCTTTCCTCCACAC TACTGTTAAATATAAAACAAAACACTTCTGTTAAATATAAAACAAAAATATTTAACACTT CTGTTAAATATAAAACAAAAATGAGAAAATCTGATGACCCTGGAGTATGAGTTGAAACAT CAGGTCCCTTTCATCTGTTTGTTTTGCTTGTTCATCAATGGTTCAATGCTCAGAAATAGT AAAAACTTAACCACAGGGTCCTCTATATTGTGAGTATTAAACAACTATTTTATAAATGAT TGATTATGACATCAGATAGGACCTAAAACTTATCAAGTACCTACTCATGTGGTGTTGATG GTGGCACTTGACATGTTATGTCATTCAAAAGTCACAATAAAACCAAATGAAGAGCTTATT GTCATCTCTATTTTACAGATAAGGAGCTAGACCTAGAGAAGCAAAGTCACTAGCCTAAGG TCAAACAGCTTTTAAAGTGATAAAGGGCAGAGTCAAATCCAGTTTTCTCTAACTCCAAAA TATAGCACCTTTCTCTTTAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTCACTTTAT TTTAACTAATTTGTTTCGTAAGCATTGCATAAGATTAGAACTAGAATGGGCTTTGAAATT AGCATATTCTAATGCCTGCCTCCTAGTGATATCATTTCTCCATTTTCCAAAGCTAAATGC TAGGTAGAAAACTCTGGTTGATCCAGATCATGTTTTCAGGCCAGGCCATAAGTTGCAGAT TGCTGCTCAATCCATTGTTTTGCATCCAGTCTAGCTCATTCAGGTTGGGAGGTGAAGTAA CGTGATGTACTCTGTGCTGTAGTCAGGTATGTTAGTTAGCATCTTTGGGTTGCAAGTGTT AGAAAAATAATCCAAACCAGTTTAAACCAAATAGAGATTATTTGGCTTACATAACTAGGA ATCCAGGACACAGCTAGATTCAGACAGGCTGGATCATGGGCTACATAAAGTCATCAGGAC ATTGACCCTGGCTCTTGCTTCTGCTCTCTTCTGTCTTGGCTTTATTCTAAGCCGGGATTC TCCATGTCATGGCCAAAATGATGACCAGTTCCAAGTTTACCTTCTATCAGGTTGGCAGTA TTGTAATTAAAAGGACTTGTCTCTCCCATGATCTCAGCAAAGGCCCCAGGGCCAATTTTC ATAGTTGGTTTCAAAATTGAACCAATCACAATGGTTGGTTCAATTTTCCTTGAACCAACC ATTGTGTCAGGAAGATAGAATGGATTGATGGGCTGAACCTGGCTTCTCTGTTCTCCTTGC TGGAAGTTGGGAATTGCTTAACCTGAGAATGAGGAAGAGTGGTCCCAAAGGGTTGTTATC AAAGAAGGAAGAAGGTATTGGGGTGTGCAAAAGCTACAGCATGCAACCTCACTACAACTT AGATATTGCCAGAAGGTGGGGACAGTCAAGGAGCCAATGTGAGACATTTTTCAACATAGA TCAAACCCTTTAAATTTCAAAGAAATTAGCCCCAGAAAGCCAGCCCAGCCCAACTAGTGA ATCAGCTAGTTAGTGTCTCTTGATCGTATATCATTTGACTCTAAAAATGTGACATTGATC CATGTTAAATTATTTTAAATTTCACTTTTCATTAAAACATTTGTACACACTTTGTGCAGA CTCCATTTTGGAATATTTAACCAGATAGACAGAAAGATTGCAGGCATTGACTATAATTAT GACAGTGTCAAGAAGTCCAGTAGTCACTATCTGGTTATTTTTTTCTTGGCCATGTCCTAT CTGTTGTATCATTTCAGACATCATTGCTGTTCTTCATTTCTCTTTTCAGGGTTCTTTGTG TCTTTGCTTTAAAACCTTTGTTTCTATTCTTAAGTGGCACAGTTTGGGTCATTGGTCTTG ACAAATAAGATCAGATTCCTTTGGTGGGCTTGGGTTTTTGGTTTTGTTTTCCCTTTTCCT CTCTCTCTCTCTCTCTCTTTATTTTTTGTTTTGTTTTTGGTCTTTAAAACTTCAACTTTT CCAAGGCTTATTAACAAAAGTAGGCCACCAAATAAGAGGAAAAAAAAAAAGAGCTTTGCT AGGTGCACTCTTCTCTATTGGAAATTATTTTATTTCTCAGAAAAGGGAGAATTAGAAGAA AGCTATTTTCCCCAATTTTCCATACCACCCATGGGAATCCAATTCAATTTCCTCTCGAAT TTTGTAGTAAAAACTAAAAGTATGGAATAAAGTTGCTGGAGTGTAGTATTCTTTTACACA GATTTGATGTTTTAAAATTCTTAGTCATAGAGCTATTTACTCAGCCTGATCCATTTCTAA TCAGAGTGTAATATAACCATTTGATGAAATAATCTTTTTTTAAGTAGACAAGTATACATA TTTAAGAGATATCAAAACCTTACCTGATAATCTAGCCTGATAGAAGAGGGCTATGGAGTC AGATGGCTCACAGCTCTCTAGCCAGAGCCTGCCTGAACTCTGTGGCTTTGCAAAACCCAA GAGAGCATTAGGTTTATTCTTGCTCTATTTTTCTTTTCTCACAGTTTCCCCTATAAAAAA TTATATTGTTTAATCCAAGGAAGTATATAAGAAATTATCATGGTATAGTTCACATCAAAT CGGAAATAAAAACCTAAATGAAAGAAATATTTCACTTATGTGGTTCTATAAAGAGAAAAA AAGAAAGAGATCTAATATAGAAGTTGGTTACCATAAACCACAGAATGGATGAATATGTGT GAAAATAGCTTGAATACATCACAAATCTTTATAAGCTCTAGGACTATTTTATTTATCTTC ATAGCAGTCCTACATTATAGCTAATAATAATAGTCTTGAGTTACACAGAAGGAAGCTGAG ACTCAGTTGGATGCACCCAGCAGGTTAATGAGAGAGCCAGGACTTGAACTCAGCCCCTTT TGTCACCAGAGTCCAAGCTCTTAACACTATGTTACCCTATTCCTCTTATAGACTCTGGTT ACTTGAACGTTGTTCATTTGTATTTCTGGGGCTGGAATACCCTAAACTTTCTGTTTCCTC AAAAGGACGTAGAATATAAAAGTTTGCCACACCTGTGCATATATTAAGCACCTAGTTTTG TTAATGCTGTTAATTGCTTATTGGCCTTGGGTTCACTTAGTTTTAATTTAACAAGCCTTT TGCCTACCAGTCTTCGGATAGATTGGTTTTGTGGAGAACGGTTGCAATCTGGATTGTAGT AATTATCTTGTTATGTCTTTTATCCTTCAGCACTCCTTATCTAACCAGATTCCTCATGAG TTTAGCAAATGGTCACGGAGCACCATCATATTCCTGCACCAATCTTGAGCAGTTCATTAT CTCAAACTTATAAGCTCCTATCTTCATTTTATAGTCATGGTACTCTAGCCTCCCTTGCAA GCTTAGAAATAGAATAGGGCAACTTTTACTATTATCTAATAGAACCAGCAGTTTACTGAA TCATGTAATCTGATGCTTCACTATACTCAAGTTTAGAGGCTCAAGTAAGGTTTAAATGGA ATTTTAGATAATTTTTTTAAATGCCAAGATGTCTAACTCATTTATTGCCTAAATGTACAA GAAGACTTTCTGGTCCTTGTTCCATCAACTTCTGGGGCAAGCCAATTGCTCTCTCTCTCT CTATATATATGACCACAGCATCCCACTGTCCATGAAGAAATGATCAAAATCTCAGTTTTT AGTTTACATTCCCAGAGGAAACTGCATAGCAGTCTATTTCTCTGTTTATTTGTTTTTTCT TTATAGTCTATACCAGTCAGTTTCCAAAGATAATTTTCTCAAGAACAGAGCCCAAGACAA GAAAATCCCATCAACCAGGAGCTATATTAGGTACTCATTATACTTGTGAAAGAATGAGCT CAAGAACTCTATGGAAACCTGGCCTCTGGGTTTGCAGAGAGGCTGCCTAGAGCCCTAATG CCCCTTCTTTCATGTATGCTTCTCCTATAATACAGGAATTCGTATGCAAATTGGCTGTTG TCCTCTTTGTTGGTCTGTTGACATGTGGCTGCTTTCAAAAAATTATAAGAAGATATCTAT TTCACATTAAACTTTGGTCATTGCATATTTTGGAAAAATACATCTTCTAAAAACATTTTT GCTTAGCAGGGATAACTACTGTCAAACTCTGGGTTTTTATTAATAAAGAATGGAATCATA GAATGCTGAACAGATTGGAGTCTTCTCTTTCCTCTGGTATCAGGATCAGGCCAGGCACAC TTGACATTTCATGATCTAGGCTTTTGCTGTAATATTGTACTTAATTATACAAGTGATGAT AATAATAGCTTATATTTATTAAGTGATTAATATATACCAGGCCCTGTGTTCAGATATCAG TTGTGGGAAGACAGACTCACGTTAACAGTGCCCTAGGACTGGGATCGTGGCCTCTGCTCC ATATACCCACTTTGACACACGTTCCCTAATTACAGTGGAAGTTGTCTGAGGGCTGGGATT CAGTCCCCTCACCGCCACGCCACTACTCTCTGGTCTCTGCCATAGTCCATGTGGTCCTGG TCTCTGCCATAGTCCATGTGGTCCTGGTCTCTGCCATAGTCCATGTGGTCCATGATGGCT CCACACTGTGTTCTTATTCCAGGAAATAAATGAGAAATTGAGGAATGAGTTTCACAGACG CCATGCCTGCTAATACCCCATCGGTCAGAACATAGTCATATGGCCACACCTAGCTAGAGA AGGTGTTGAGAGGTGTTATCTTTATACTGGTGACTGTGTACCCAGCTAAAACTGTGCTGT TGTGAGGAAAAAAAAAAAAAAGATTATATATCAGTTACCAGTCTTGGCCTCATTGTGTCA TATCATTTAATGCTCCTAACAACCCCTTTTGTAGGTATCTTATTATCCTCATTTTACAGA GTAAGTAAATTGAGCTTAAGGAACTTGCCTAAAACTTCCTGCTGCACAGGGCTACATGAT TCCAGGGCTGAAACTTTTATCCACTGTTTTCTATTCTATTTTGGATAAATGCCATACTTT TAAGAATTTTGTTTTTTTTTTTAATGTACAATTCAGTGGTTTTTAGTATATTCAAAATGT TGTGCAACCATCACCACTGTCTAATTCCAGAACATTTTTATCACTCAAAAAGCCCCTATC CATCAACAGTCACTCCCCATGTGCCCCTCGTGCCCCTCTCCCCATCTCCTGGCATCCACT AATCTACTTTCTGTCTCTATAGACTTGCCTATTCTGGACATTTCATATGAAGGAAACTGT ATATATACATATATATACTTATATGTATGTATATATATATACACATATATATACTTATAT GTATGTATATATATATATGTGTGTATATATATATATATATTTTTTTTTTTTTCTTCCTTT GAAATGGGGTTTCACTCTTGTTGCCCAGACTGGAGTTCAATGGCATGATCTCGGCTCACT GCAGCCTACACCTCTTGGATTCAAGCTATTCTTCTGTCTCAGCCCTCTGAGTAGCTGGGA TTACAGGCGCCCGCCACCAGGCCCAGCTAACTTTTTTTTGTATTTTTAGTAGAGATGGGG TTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCCTGCCTCG GCCTCCCAAAGTGCTGGGATTACAGGCGTGTGCCACCACTCCTGGCAGGAAATCAGATAT TACGTGGCCTTTTGTGTCTGACATTTTTCACATAGCACAATGCTTCCAAGGTTAATTCAT GCTGTAGCATGTATCAGTACTTCATTCTTTTTTATGGCAGAATAATATTCCATTGTATGG ATATACTGAATTTTGTTTATCTATTCATCAGTTGATGGACATTGGGTTGTGTTCACTTTT TGGCTATTATGAATAATGTTGCTTTTAATATTTGCGTACAAGTTTTTATGTGGACATATT TTCAGTTCTCTTGGATAAATACCTAGATGTAAAATTTATGGGTCATATGGTAACTGTATC TTTTTGAGGAACTGCCAGACTATTTTGCAAAATGGCTGTACCACTTTGAAAGTGTAAAAA CACATTTTATACTCCCAATAGCAATCTCTGAGGATTCCAATTTCTCCACATCCTTGCAGC ATTTGTTATCATCCATCTTTGTTTTATTACAGCCATCCTAGTGTGAATCGGCGTCTCATT GTCATTTTGATTTGCATCTCCCTTAATGACAAATAATGTTGAGCATTTCTTCGTGTGCTT ATTGGCTATTTGTATATCGTCTTCTTAAAATATCTATTCAGATTCTTCACCCATTTTCTA ATTGGGTTATTTGTCATTTTATAAATCAGTTGTTAGCATTCCTAATATGTTCTAAACATA AATACCATTTTAAACAGTAAGTGCAACCCATTTTGATATAGTTAAATTGTTCAGTTATTG TATGAATGCACCAATTAGTAGATTTGACAGAATTTCCAAACAAAATAATCAGTCCAGTTT GTGAGTACAGCTAGAACCTTAGTGCTAGTCCAGTTTGGGCCAAAAATTTTATTCTGGTAG AAGGGAGAGGGCTTGCATAAGCCTCAGCCATATTTTAGTTTTTCTGTTCATCAGAACTCT GACATACTGGTGAGCTCTACAGTGTTTCTCAAAGCTTACTGTGCATCTAAGTCATGTGAA ATCTTGTTAACGTTGCAGATTCTGCTTTAGTAAGCCTAGAGGAAGCCTGGGATTTCTAAC AAGCCCTCTGCTGATACAGAAGATGCTGGTCCATGGACCACACATTGATTAGCAACATTA GAGTATTAAGTGTTAATGTGGCTGTCTAGAACCTTGAGTCTAATTGTTATATGAACCAGA TTGCTTAGTTCTAATCTCAGAGAGAGTAATGTCCTAGATCCAGCCTTTGGAATTGACTCT TGGCTGCCACTTACCAGCAGTGTGTTTCTTTGAGCAAGTTACTTTACTGCTCTCAGCCAC ACATCTGAAACTAACAGGTAATTATACCTCCTTCTCAGAGTGATAATGAGGATGAGGTGA AATAATGTACATAAAGCATCTATTACAGTTCCAGGTATATGAAGGGCCTTGGTAATTGTT GGCCCTCTTTTTTCCACTTGCCTTCCGTAATAGAGACTGTCTCCCTCTGATTGTTCAGTG CAAAGGCATCATCATCACTGGAGAGACAACTAAGTGTCCCTACCCTACTTTGTTATATTG TCATGATTAGATACAGAGAGTATTACTCTGTTTATAGTCTGTAGTTATTCTGTGTATGTT TCATCTTCTCTACTCAACAGATTCTATGTTCTTGGGGATTAGGACTATATATTGCCTTCT GTTTGAATCCCTATGCGACCTCTCATGGTGTATCCATAGACTATCCCATTAATTAATGCC CACAGAATGAATCAGACAGCCCAAGTCCATAGTAGTAGAGATAGTAACTATAGAAATAAT AAAGGAAACTAACATTTGTTAAGAACTTTGTGTCAGATACTATCTTAAGGGCTTACATGC ATCATCTGGTTCAAGCCCCACAACCGTCCTTTGAAACCCCTCCATTTCTTGCCCTTGTTT TACAGAAAAGGCAGCTGAATTTTAGCTGTACTCAGCAAGAGTGAATGCCCTCTGCAGTTG TAAGAGCAAAGTTCTGGAGGCAGGCTGCCCATGGTCTAAATCCCTGCTCCATTTTGTACC TGCTGGGATTCAGAACACTTTAATATTCAAATGCATGATCATCTGTAATCATTAGTGCAG GTCTCATGGGATTGTTGTGAGCTTGGTATGAAACAATATGTGAAAAATGCAAAAAGCAAT GAGCACAATGCCAGGTGCTTAGAATTATTCAGACAATGGTAGCTTTGTTTAGTTGTTGAT TTGTTAAGTTACTTATCCTGGCCTTACAGTAAGTAAGTGGCAAAGGAGGGATTTGAACTC AGGCTGTCTATTTCAGTGTCCCAGTGTCATAACTCATCAACTCTAAGTTATGTTGTTGCA CATCTCCCATTTCAAGTAATGTGTTAAGGTGGGAACTGGAAATTCATGTGTCTATGTAAA GAAAGTCAAAAGTCAAGGTGGCTGCAGAGACAGAAAAAGAATGTGAGAGGCACTGTATAA TGTATCACTCTTTTAAAAAGATATTTACAAGCTCCAATATTTGTGCTAACACGTTCTCTA AAAGCATTTGTATAGCTAGTGCCAATCCAAGGGAAGAGGCGCAAGCAGAGGATGATCCAC ATTTTGGAATGCCTAAAACTTACTTCCTTTGGGGATGCAGGGACCCAAGGGGCCTCATTA AGGAAAAACCCTCATTAATAAAAATAAATAAATATCTTACTTGAGTAAATTATACCAAAG CATATTACCATGTGAACATATTGCTAGGGTCGTCCTCAGAGCCCTGAAAGGGCCCCGAAG CTAAACTTCATCCACTTCATGGTGAATCCTCCTATGGCACAAAAGTAACCAAAACTCTGA CTGCACAACAGGAAGCCTGGCCTGCATTCATGTTTTTCTTCACAAAGGGACATTTTTTTA ATTTCTTTGTCTCAGTACCTCTATTTTGAACATTAGTAATAGGCTATATGGACCTCGAGC TCACAGGAAATTCTGGCAGATAACAGGCTTCCCAGAATAGATATATTAAGTTATAAAAAA ATAAAAAAATGAGGCAGACGGTATAGGTTTTTCATACCTACTGGCAGGTGGCACAGAACT AAATGTTGGAGCATTTTTATAAGCAAGATTAAATTGACTCATGACAGCTGGTCACTAAAA TACAGGAAGTGCAGATCTGGTTGAAAGCGAGAACACACTGGTGTTCGTAAAGTTTGCATC ACAGACTAGAGCTCACTTTTTCTTTTAAGTCTGCCTTAGCGACACCCTTATTTGGCAATG TCTGCCATTTATCACTTGCACACAAGTAGATGTTCAAGGAACACGCAGGTCAATTAGTTC TATCTGCAGTGCTTAGGTATGAGTACTGTGGGTGTAAACAGAATCGGTGAATAGACTTGG CTCTCGAGAACATCAGACATGTGACTGCTAGCAGAGCCTTTTCGGTCTCCACTTGTCCAG TCCTCCCCTGCCTAAAGCGACAGGATAAATAGACGTGGGAGCTGGATGGCCATGGGAATG GATAATGAATCTGTCAGAGACAAGTGGGACGTCACAGAAGTCTGCCCTCTACACATCGTG AGGCCGGAGGTCACAGCACCAGGAATTGACAGCAATCTCCCAGCATTGTGAAATGTTTTT GTTTTTTTGTTTTTTTTCTGGCAAGGGCTCTAAATCACAGGTTTTCACATCTGATTGGAA TGGGGCTGGTGAGGATAAACTGAGTTGTGGAAAATGAAAGGGAGTCCTCTCCAAACAAAG GAAGTGCCCTGGTGCCTCACCCTCTACTTGCAGTGTTCAGCCCCAGCACAGCAATTGTTA CACTGACTAAGCAAAGACAGCCCAAAAGCTTCACCAGATGTGAAGTTACAGTTTTAGCCA ACGTTCAAGCAATGCCCTTCCTCCAACTTCAGCTGGACCAGGGTGGCCATCCTTGCATGA GACATTAAAGCTAAAAGAGGCACATTTCAGAATAATTACGCTATGCAAATGCTTTGTTTT TTTCTCTCCCCTGAGCTGTGTTCTTTTCCTAGGTCTTTCAAACATTGTTTAAGAAGCTCT TGTTTTGGGTTTCAGTCATCTGATGAATCCCCTGGAGTTTAAATGAAATTAAACTGGGTT TATGATATCTCACAAATTTCATAGCGTCTCCTTTCTCCAATGTAGTGTAAGTTATGAAAA CCAACAATTAGGGCATGTGGCAGTTTTCAACACACATCATGGAGTGTTTAATTTAGTACA ATGTCTATTAATTTTTCATTAATTAGTCCATTGTCAAATTAGACACAGTAGAACATGCAT ATGACATTCCTGCTTTCAGGAAGCTTACTTTATTATCATTTGTCTTAATCGTCTAAGTTT TCAAGCACTTATTATGTGCCAAGAACAGCAACACACACTAGGGATATTACAATAAATAAA GCAGACATGACTGCTGCCTCCCAGGAACTTATCCTCTAGTGAGGATGACAGAATAAGCAA TTAAAATACAGTCTACAGTCTATAGCAAAGATGCTATGGGTTTTATTATGCAACCAGCCT TGCCTTATGTCATAGGAGCACACAGAAAAGGCATCCTGGTGGACCAGAGAAACATTCCAA CTATGGGCAGATATTTTTTGTATACCAGAAAGGAGCCAGCCACTGACATATACAGGTTAA TATCTGAAGGGAAGAATTATCCTGATCAAAGAGGTAGGAATAGGAGAGTAGAATGCTGTA GGCAGAAGAAACAGCTTATAAGAGTACCTGAAGGCAAAGCTTGAAGAACTAAGTGTAGAG TTAGGAGTGGTACAAATGAAGCTGGAAAAGGGGCAAGAGATAAATTGCAAAATGAACTTG CAAGCCATGTAACAGAGCTTGGACTCTATCCTGAAAATAATGGGAAATCTTACAATGGTT CTATTCCAGAAGTGACCCAAAATATATTTGTGTAAAAAAATATTTGGACTATTGTGTTGA GATTGGGTAGAGAGGGGCATGCCTGGAGCACAAAATTCTGTTTAGAAGTTCTTGTAATAA ACCAGATCAAAGATGATGATCACAGCTAAGAAAGTGATTGTTGCTAGAACTGTATGGATT GGAAAGAGAATCAAGGAAGAGTGCATTAGTCCATTTGCACAGCTATAAAGAAATACCTAA GACTTGGTAATTTATAAAGGAAAGAAGCTTATTTTGGCTTACAGTTCTGTAAGCTGTGTA CAAGAAGCGTGATGCCTGCATCTGCTCAGTTTCTGATGAGGGCCTCAGGAAGCTTCCACT CATGGTGGAAGGCAAAGGGGAAGTTGACATGTCACATGGCAAGAGCAGGAACAAGAATGG GGGAGGGAGGTACCACACTTTTTAAACCGCCAGATCTTGCAAAAACTCATGGAGGGAGAA CTCAGTCATTACCACAATGAGGGCACCAAGCCTTCATGAGAGATCTGCCCTCATGACTCC AATACCTCCCATCAGGTCCCTCCCTAGCATTGGAGATCACATTTCAACATGAGATTTGGA GGGGACAAAATATCCAAACCATATCAAAGAGGAATCTCAGGGCATGGTGAGAGACTGACT AATGCCAGATTAGATGTGGTAGGAAAAGGAGAGGGATACATCATTCTTGCCTAACTGGGT GGAAGATGGTACAATTTACTAAGAAAGCACAGAAGGAAGAATGGGTGAGGCAGGAAGCCA AAGAGTTTAGTTTGGGGACATATTGAGTTAAGTATGTCCAGGAGGCATTTTGATGAATAA GTCTGAAGCCTGGGAGAGAGATCTGAGATGGAGATACAGAGCCCAGACTTACCAGCATTT TGATTAGATATTCTTCATGTGGTGTAATGGAGGGAGGGGGCTCTATGGACCCCAGTGGGT AACAGAGAATCTTCGAATATCCTAAAGTGTTTTCACACTTTGAGCTTCCTTTAAATATAT TTATTTGGGGTGGGGAAGATGATGTGAATTTGCTTTAAAAGGTTTGTAATGCGAAGGAAG TTAAGGAGTGCAGACAAAGATTGAAGGGACAACTAGATAAGAGTGCGCAAGGAGAGTGAG CTGGCTGTGCTAGGCCAGAACCCAGAGAACAGCATGTGTAGTCAACAGGCTGAAGAGGTT CCTGAAAACGAGCTTGGGTATCCAGAGGGGAGAGTGTCAGGGGAGAGGGAGTGGTCCAGA GTCCCAGCCCCTGAGGAAACAAATAAGGCATGGAAAAGTATCCATTGGATTTTCAACAAG GAGGTCGTGGGTGATTTGACAAGGGAGGCTGTGGACATTTGGAAGGACTGAGTGAGTGGG AGATGAGAGAATGGAGATGGCAAGTATAGGAAACTCAAGAAGGGAGGGGAGAGGACTTAG GAGGTAGCTAGAGAAGATGACCAAATGCACAGCAGGTATTTCCTCACCTTAAGATGGGAG AGGCTTGTGCAATGAGTGAGAAAATTTATAAGTATGAAAAGCCTTTAGTAACAACCTATC CAAGCACACGGACACATTTAAGGAAATCAGAAGAGTAGAACTCAGGGTTATGTACAGTGG TCAGGATGGATTCAGGTTATGAATTGAGTTGAGCCTTGAATGGTTAATAAGCTTTAGGAC AGCTGAGAATGAGCCATTAATTGGAAGAAATCTGAGAAAAAATAAGACTAAACATTCATC TATTCTCCTTTTACCTCCTTTTATTATTCAAAGAATATCTTCTCAGCTAATATAATGTCT TTAGAATGGAAATTGCCTGTAACTCAGAGTGACTACAAGTATGAAAGTATTAACAGTTAC AAGATACATAATCCAATTTACAATTACTCCTTGCATTCTTGATCTTCACGCAGGAAACCA GCATATTCTTTGGGATCACATTGTTCAATTTCCTCATTTGGAATTTTTAACACCAGATAT GGTGCTAAATCAGTATAAGCTGGTGCTTCTATCACTTAGGTTTTAAACATCCTCCGTATA TAGAAACACACCCATAAATAAAGGTGTTAATGTTGGAAGGAGAAAGATGCTTTAATAAGC AACCTAGCACAAGTAATTCCCTGCATATAGGAGATTATTATAGGACCTAGCTCATAATTA AACATTGCCTATTTAACTGAATTATTTTTTATCTTACCTTTTTAAGGAATATACAAATGT TCATTTTCAAAGGTGACATTTATGTGTCTAAGTTGAACAAGCTTATTATAATTCATAAGT ACACAGAGAACAGATTGTAGCAAGAAGTATTAAACATTGTAATAGACCCCCGAGAAAGCT GTAGCTTGGTCTTCCCAGACAGGTTTGAGTAGATGGTGATTGCTTTAGGACTACACCTTT TAGTTAAAAGAGAGCCCAACAGCTTTCAGTAATAGTCTTAACCATTCCTTTTTTTCCTTG CCGTAAGTATGGGTCAGTGTTCCAGAAAGATTATGGAGGCACTAAAGAAAAACTTGGCCA TTGCTATACAGACATTAGAGAAGCCAACATGGTTGTTAAGGAGTCTTATCTTCCTACCTA AGAAAGAGCATTCTGTTCTTTTTCCCATTCATGGCATTTGGCCCAAGAGAAAAATAAAAT AAAATAAAATACTATAATATTTTTTGGTCTTTATGAAACTTGATTTTCTATATTTTTGTC CTAGTTCCTGGAAGAGGCCATGTTTCTCTCTCACACACACACACATAAACACACACACAC ACACACTGTCAATCTCTCTCTCTCTCTGGTTCTGATTCAGACCTATCTTGGTTCTCTACC CCTGCCCAGGCTGGATGCCCAGGTTCTCTCCTATGTGTGGACCATCTCTTCCCACATACA TTATTCTGACCTCTGGTTGTGGCCATTCTGTCAATGTAGGTTTTACCTTTCCAGAGGATA TGGTGTGATACAGTTTATATCCTGCTGCCTCAACAAATATCAAGTTAGCCACTGCAATTT TATAGTCAAAGACTTCGGGCATTGGGATGTATTTTTGTGGAAATTGCATATTCCATTGTT GCCTCTCATATATCATGGCTTTATTCATAGGCAGCAAAGGCCAGGCCTTGGCTAATGACT TCCAAACCCTGCCACATGAAGGATTTTTTTTTCTCCTTTAGGATTCTAGGCATTTTTAAT TAGAGTCATTTGGCCTGTTTCTGAGAGCCCTTTGTGATTCTCCGATTTGCTGTGAGTGGG ATGTCTGAGGATTACTGTGTCTCACCCCCCTTCGGGTCTGTTAGCAGCCTTGGTGGAAAA TCTCTTCTGATCTGAGGAAATGTCATTTTAGAGTGCAGAATGAGAACACTTGATTATAAT TTCTTGGGTTTCTAAGAATAAGTCTGAATAGCAAATTATTTTAATGGTTATCTTCCTTTT TAAACAAATAAGAATTGTCTTAACGATTTAAAGAAAAAAGATAACATTGTTCTTTAAACC CAAACGAAGCCCAGATGAAATTGTCATAGATCTGTTAATATCACAAAAAGACCTTTTCCT AAATGACAGTATTTTGGAACCTGTTGGGAACCCCTTGATTTTGGAGCACAGTTATCTTGC GGGAGCTTCAGGCCCCCACTGACTTGACTGCTATTCGGCTTTCTCAATGTACAGTGTAAG GACAGACTACATTGTAACAACCCTGCCCCCTGCAAACGGCTCTTTTGGGGAAGATTCTGA GGGCTGGGCCTGCAAATCTATCTCTTACTAAATGCCTCTGTGTATCACTAAAGCACTGCA TGGTTTGAGGAGACAAATCAGGGAAGCCTCAGTGGTCACCAAGACCAACTTATCTGACAA TGAACTCTTTGTCTCTCCTCTGCCCAGGTGCAAGTGTAATCTCCATGCCACTGTATGTGT GTATGACAACAGCAAATTGACATGCGAATGTGAGCACAACACTACAGGTCCAGACTGTGG GAAATGCAAGAAGAATTATCAGGGCCGACCTTGGAGTCCAGGCTCCTATCTCCCCATCCC CAAAGGCACTGCAAATACCTGTGAGTAACTTTGCTTGGTAACAGCATATTCTGTGCACCA TGAGGTGATAGTTCCTCTCAATTTTGCTTACAATTGTGATTTTATTCCTCTTACCAGTTG TCTCATTCTTCTTTAAAGTGCAGCGAAAGTTTCAGTCCCTATCTTACCTCATGTAGACAT CTTTTAGCACTCTGATCATCAGTAAAATTCAGTCATCTAACATTCACATCAAATGTGTTG GGAAATGATACTTGACATCACAGAAGGAATTTTTTATAAGTGGATGAGACAGGAGGTGAT TTTTTTCCTCCCCCAAATTAATTTCCTATTAAAATATCAAAGGCCTTGTAAACTCTCAAT CCTAATTTAATTTTAGCCATAAACAATTTACAGAAATTATTTGAATGTTTACAGCCCCAT TTCCCCTACTGAGTATCCTGAGAGATGCTTTGTCCAGAATATTTCTCCCCACTACAGTTT TAGCTAGGACCTAACTTTGCCTTGTGAAAAGTTTGGCTGTTTCCAAACTCCAGCAATTGA AACATACCTGCTTTGGATCCTGTGTGTAGAGGCCCCCTTTGGATAAAGAGCATGACTGTA GGCCTGTGGGGACCACATTAAGAAAAAAGATTTTTCTACGCATGTGAAAGAGTGCAAGCA TTATCCGCGTTTACAGAAACCATCTGTGTGCCCCCACTGAAATCCCTGATTCCCCATAGG AAAACAGGCTCTGACATGCTCACAGAGAAATGTGATTATTTGCTGAATAATTTGCCCAAT TCCATGGATGGACCAATTAACTACCTGCAACAGCCCAAGGTTTGCACTCTTTAAAAAGTA GAGAAAGGGGGAGATTAGAATGTCCCCATTCAGTGAGAACTAACAGAAGCAGCCGGACAG TGAGCACAGGAGAATCAGAACTTGAGAAGCCACTGCTTCCGTAGAAGGGTAAGAATGTTA TCAGGCACTTCAAAGCAGCAGCTGTGAGAAACCAAACCTAAGAACTAGTATCATAGGAAC CAGGACTTTATCAAGTTAAACGTAAGAGTAATGGACCAAGTAACAAACCATGAAGTATGG GGGCATGAAATTATGATAACATTTCTATGAAGCAGAAAGAAATCCTTCAAAAGGTTTAAA AAAATCCCTCTTTGTAAGGGTATTCAGTTGCTTTCAGTGTTAAAGAAAAAAAACTTGACT TCTTGCTCCTAAAATTAATACATTAACGCTCTGTTGAGCAGAAACGTGGATGTTTCAAGG TGATTTTATTGATGGAGACTCTGTGGCCTTTCCTCAATTGTTGAGGGCCACAGACTCATG AATTTGAAAGGGATCTTGCAAGGTTATTTATTGCAATACCCTGTGGCTGGCTACCTAAGA ACTCCTATGACCCCAGTTGTCAAATTTAGTTTAAAGCTTTCCTAAAGTAAAAATGGCTCA GATTTCCTCTTTAATGTCTGCTCCTTCTTTAGTAGAAAAGGCTGGAAGAGTGTGATGTTC ACAAACACTTCCTGGCATTCTGGCTTGTCCTCAGGGCAGGTCAGCTTGCCAAGACCACTG GAGAGGCAGCAGGGGAAGGCTGCTGTTGAAGCCCTCAGCTTCTATTCTAACGTGACCTTG TTCTTCTACCCGTAACTGTACTTTGAAGTTTTTATTTCAAGACATTTTCACTGGAAAGAC TTTCTTGTTTCATCCAAGCTTTCGCATTGAAACTGATTTCTTGTTATTCTCTTGTTATAA TCATCATGGAAATGTCTCCTACCCCGAATCCTTTGCATATTGAAGATCACCAAGTCACTT TCTGACCAAAGGAATGAAACTTCTTTCAGTTTTCCTTGTAGGTCCAATTGTCCACCTATC CCTTAGTTTTACTGGTTTTCTGTATACATTTTGGACGTTTTTCCTCATTGATGTTAAAAT AGGCAGGTGATGGATGGACCCAGTGTCCAAAGGGGTTCAATTCAATATTCCAATCATCAG CATGGCAGAAATTAGATGAAGGGTTTTAGAAACTATCTGCAGATCTGCAGTGGTCCAGTC TTGCAATGGGAATAACCCCTTTGACTAAATCTCTGACACATCAGACTCTGCTTTAAAGCA TCTGAGGATGGAAGTAAGCAGTTTAGTAGTTTAGTGCACAGACTCCAGGCTGGAATCCCA GTTTCTCCATTTACTAGCTATGTGACCTTGAAAAAGTAAGCTAACCTCTCCAACACTGTT TCCCATCTCTAATGCGAGGATAATAACAGTTATTACCTCCTGTGGATTTTTAGATGGTTG ACTAAGCTAACGCATGTCATATGTTTAGCCTAACACCTGTCACAAAATAAGCATTCAAAA AATAATTTATTTTTAGTTTTTTTCATAAGACAGTCTTGTCCATTGTTGGACAGTTTTAAC TGGTATAAAAGTTACTTCTTATCAAACCTTTTTTTTTTTTCTTTTTAAGTAGTAAAGGAA GTATATCGACCCTGGCTTTATTTCTTCCCCAGATTAACCATTATCGACTCCAATTCTTAT GTGCTAATGTTTTCATGTCCTTTACCTGGTTGCCTGCTCTGGAAGTCCTCTAATTCATTA GTGTAGTACTTCCAGCCAAGCACAGGACCTTCAGCAGTTTTATGATTCTCACTTCATATT GGCTTTTTCTTACACATATGCATACAGGTACACACACACACACACTCACATGACTCTAGT GGGTACGTTACAAGTCAGTTATCTATGAGGGATACTTAGGATATATCATCCCCTAACATA ACACAAAAGCTACAACTTCTGGTCCCTCAAAATCAACTTTTCAGGGACCTAGAAATGCCA CTCATCCTGGATAATCTCTAGATTTAGCAGAATATCAAGTAGCCAGGATATTTTTCAAAT AGGATGACGAGTTAGTGGGTGCAGTGCACCAGCATGGCACATGTATACATATGTAACTAA CCTGCACAATGTGCACATGTACCCTAAAACTTAAAGTATAATAAAAAAAAATAGGATGGT CAGTTTCTGTTCACCTTCACAAGTTTTAACAGAACAACTGGGAGGTCTTAAATTAAGTCA GGGAATGACAATATTCTTCCCCAAGACACTCAGCCCACCACTCAGGGATACCATAGATGG GAACTTGCTGGGAGTCATTTGGCTTTGGAGGTCCTCTATTCTGGAGCAGTTCAAGACCAC TGTTGTATGAAACATGTAGAGCTAAGCAGAAGTGTCAGAAGGCCAACATTCTAAAATATA GCCACCCCAGTCTGTGAGACACACCACATTTCCCTATGCTTTTCATGACAATAAACTTGA CAGAGGCAGAGTAACTTTTGTGATATTTTTATTCATCATGCTTTTATTCAAGACCCAGTG TGTTTTCTTGGACTTTTAAAGCCATGCACATGTATATCAAAATCTTTTCTTTCTTTTTCT ACAAAGCTTATGTTTTATAGAAAAGACATTTTTCTTCTCCTTATTGATCTTCATTCTTTT TTGATAGAATTCTATTTTGGATGTCCTTTGAATTTTATTTCTGTCTTCCAAGTAATAGCA ATTCTGTCCAACTTCATGCTTAATTATGATTCTCTTGATTCCCCATTGTCCAGCTCATGA ATAAAAGTATTAAATAACTCTTTAAACTCTGATCCCTATGGAATAACACATGTTTTTCTA TATATAGATGCTAAAAGCTTAATAATCACTATGTAGGAATCCTAACTTCAGCAAATATAA TATTATACCTATACCTCTCCTTCTCTGGCTATGTTCTATGACCCATAAAAGCACTCCATG GCCAGCTAAGTCTGAAAAATGCTGTATACTATAGACTATTCATATTACATTACTATAATA GAAACATTTGAAAAGTCCTACAATAAAACAACCTATTTTACCCAATGTTTCTCAAACTTA TTTGCTCCATGGACCATTCAATAACTTTCTATAAAACACTCTTATGGGGACATGCTGAGC TAAACAGTTTCTTGCAGCCTAGCCATAGAAATGTCATGGAGATAGACAGAAAACTGAGCA AGTTCAGCTGTATTCAATCTTTTCCTTTTCTCTTACCCACATGGTCTAATTGTCTTCAAA GAAAGAAAATCAAATTGGTCTGACTTTGACATTATTTGTTCATAAATCTAACTTGAATTG TTACACAATATCTAGGGGTCCTCTGAGTGATGGAAAGTAATTTGATGATTGTTCTATTAT TTTCTCTGGTATCAAGTTTGCATTGACCAATTTATATTTTCCCAGGTGTACACATGTATG TGTCCTTATCCAGACAATTTCCTAAGTGCTTTATATACATTAGTCCATTCTAAACTCAAA ATAGTCTTACAAGGCAAATACTACTATTTTAATTTTAAACACATGGAATATTGTGATTTC AGAGGAAAAAGATCTGTTTAAGGTTTGCACAGCTAGAAAGGGTTAAAGGGAGGATTTGAA TCCAGGTGGGTCTTGACTCTGAGGACTGCACATTGCACTGTATTGCTGATCAAGTTAAAT TTGGATGACTTTCTCTGTCCTCCACTGGGATTTAGGCTCCATTTCAATGCCTATTTGAAC AAGTCAGTTTTCTCTAAACCTGCCCTCTTCCTTCATCTCTGCCTGTTATTTTTCTGCCTT CAAAGATTCCCCTTCTATTAGTCTTTTAAATCTCCATGTTCCCCACCCCGGCTGTTCTCA GTCTACAATTTTTTCTTGACATTCTAGCCTATTCTTGTGGTTTTAGATCTTAGTATTATT GATTTAGTCGTAATCAACCAATTCTAACTTCAATCTTTCTAATAAATTCAGAAAAATTTT TCAGCTGTCAGTAAAGATCTCAAAGTCAATATGCTAGATACTAAATTCATTTCTTTCCCC TAAAGCATTTTTCTCTTCACTCTATATTGAAATTCTGCTCATTTTTCAAGACTGCTCCTC AATGCCTCATTGAAGCCTACCTAGACTCTCCTATGCAAAATCAATTACTTCTGTCTCTCT CTCAAATATTGATAATGTGTGTAGATTTACAACTGGTCAACTATCTTTAGCCAAAATTAT TATAATAATGATAGCTACCATTTATTAAATTTACTACAGGCTTTTACACTTCATAAAGTA CTTTATGCTCTTTATTGGTTTAAATCCCCACAATATCCCCATGAGATATGTACTATTATT ATCCTCATTTCACAGATAAGGAAATGCAGACACAGAAAGGTTAAGTTGTTCCAAAGTCCC ATAGCTAATGTATGACAGAGCAAGATTTAAACTTAGGTCTGTCTCATTATAGGAACTAAA ATGTGAGAAATTTAAGAATAGGTCCATGTTTTATTCTTGGTCTTCATCAACGTTTGTGGA ATAAGTTTTTTTTTTTTTTGAGATGTAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAAT GGCATGATCTTGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCCACCTTA GCCTCCCAAGTAGCTGGGATTACAGGTGCCCACCACCACACCCAGCTAATTTTTTGTATT TTTAGTAGAGAAAGGGTTTCACCATGTTGGTCAGGCTGCTCTCGAACTTCTGACCTCAGG TGATCCACCTGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCA GCCCATTTGTGGAATTACTTTTGTGAGTGGATAAGTAAACCTAATAGCCCTGTAATGTGC ACGTGGCTACACTGGCTTCCCATTGATATTCTTGTATCTCCTGGAATATGTGGCCTTCAC AGGTCACCAGCTCCAACACAAGAGCCTTCAATCTCCTACAGGAGAGACCATCTGAGTTCT TGGAGGAACTTTAATGGGAAAAAGTCTCACTGGTGCTCATGGCCAATCGAACCATCTAGA TAGCATATCGGATGGCGGATTTTCACAGGCCTCCCCGAGGGTTATTTACTGCCTGGGTGG CTTGACTACCAGCCTTTCTGGCTCAGAATCCTAATTTTGTCAGCGCAGTAAGAGAGGTTC TTCCACATATGTGTATGACCAAGCTGTAGGCCCAGTGTTGAAAACCGGAATACCAAGTTA TTCAGGTACAACCACTGATCTATTGTCTGTGGTCCCTCATCTGACCAGATATGATTTGGA ATTCAACATCTTTAGGATTTTACAAAGGTAATACAGTGCACATATATTACAACAATACCC ACAGCAGAATATTAGGCAACACCATTTAATCAAACATTTTAATGTTTCTACAGCAAACAT GATTATTCTCAGCAACTGGGATGAAGTAAGACTATAAATAATACCCTCACACAAGTTTCA GTACAGTTTTGCCACCAAGTTAATTCAGATCACAGTAGGTCATATTGCAGGTACATGTTG AAAAAAATTTTAATTTTCATAGTTTTTTTTTTTTTTAATTTGAGGGCTGAATAATAAAGT TCAGGGCCTGAAATAAATGGAAAGACAGTATAGAACGGTGGCGATGGGCCTGAATTCTGG TACCTGGACTCTGGGCTCCAGTTTCCTTCCCAACAGACTGAGATGATCTTGGGCAAGTTA CTCAGCTTCTATGTGTTTGAGTTTCCTCCATCTGTAAAATCAGCCTGATTATTGACGTCA TAGGATGGTCATAAAAATTAAATGAATTAGTACATGTAAGGCATTTAGACAGTGCCAGCC ACGTAGTAAGCAGCAGTGCAATTACCTGCTACAGTCATTATCTTTTCCCTGAGACCCAGC ACATAAGCAGCAAATTCTCCCCTTGGAGACAGCAGCTATGTAGGGAGATATATTGTGGCC AACTGCCTGTCTATTCAACCACAATATGAAATAACTGTCATGGTGTTCAGATTATTCAAG TCCTTATGGCCAGTGTATTATCTTTCCTGTAATTAAGTCTATGTGCAGAGCCAGATAATA ATCAGGAGGTTGCTTGGTGAGCATGGGATCAGGAAATTTGAATGACTTGAATGTTAATAA CATCGGGCTGAAACATCCTGACCCATCCATCCTGCCTCAGGGTCAGCCTTCTTCATGCCA ACAGGACACTGAAGGTCTGAAAGTTTGCGGGTTACCACTCCCGCTCTTGAGACCATGCTA GGACGGTACTGTCACCATATGTGTCAGGATGCTCCTTTTGTGAGGCTTCCACCTTCTGAT TAGCTAGTTCTTCCACTCTTCAGATATGCTAACATGGTAAGTCAGGTTAATGTCACCTCT GTTGAGTCTGCCACACACACTCAGGCCCCAAGCTCTGCTACTGCTATAAGATGACTGTAG CCATTTCTGCTTGGATCATTTATATGATGATTTCACAGCATACATCTTTGAAGGTGATCT TATTTCCCTCACTTTCAAGTTTCTGGGAGACAACTCACTGCATCTCCTATCAACAGCAGT TTATACTAGGGGCCAGGACTGGAAGAACATTGGAAGTAATTCCTCTGCAATACAAATGAA TCTGCAGAATGTTTTCTTACTCATTATCTGCGTTTTCTTCAACTTGAAGAAGTTTTTTTG GAGTTAGAATTCCTGATGGCTGCAGTCTGGCTATAAGATCTAGTTACCCACTTGATGGGT TTTTCAAACCATCTATCACAACAGTGGTAATTTTTCCTCTCAATTTGAAGCATGCCAAAT CCTTATCCCTTCTGCTTCCTTCCTGATGAAAAGCCGCTGAATCTTCCATTGATTCTCAAA AGGAGTTATGGCACTGTATTAATCAGCTTCTGAAGAGGAGGGTATTTATTTTTGAAATCA TCATTTTGACTTCCTTAAGCATAACAGTGTACCCTTAAGTTATTTACTTGGTTGGGGGAG TAGTAAACTTATTTAAAAAGAAGAAAACATCACATTATTATATTGTGTAATTCTACTAGG TTCTCACCCCCCTAATTGCAGCAGAATATCTTTAAAACAAACGTAAGTGGGAGAAGGAAG GGCTGATTGAGGAAAGAATAATTGCAAGTACCTGCAAGACAAGTGCTTTCTCATTTTTTC AGCGTATGGTAGCATAATAGCCCTTTAGCTTACTCAACACGTATGTATTTCTGTGGTTGA AGTGACATTTCTGTTCTAGAAGAAGCGTTATTATTAAAATAGTACTAATTGCAGAAACTT CTGTTAAAACTCATGCACTGGGGCTGAGCGTGGTGGCTTATACCTGTAATCCCAGCACTT TGGGAGGATGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAGGACCAGCGTGGCCAGTA CGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGACGTGTTGGCATGTGCCT GTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGG TTGCAGTGAGCCAAGATCAAGCCACTGCACTTCAGCCTGGATGACAAGACTCTGTCAAAA AAAAAAAAAAAACCTCATGCACACCTGTGCTTCATTTCCTCTGCACAAATTTAACAATGC CTCACACAGGGACTAGAAGTTACATGCTCTGATGTTGACTATAAAGGGATGGACTTGGAC AAGGCACTTGAGTCTCTTTGTGCCTCTTCTATAAAATGAAAGGGCTGAAGAAGATGATGT CTTAAATCCCTTTCAGCTTTCATTTGTTATCACTCTTTCTGAATTAACTTATCTAGTATC TTTCCTTCCTTCCGTTCTTTTTAATTTACCTGTCATCTCTTTATCTTTCCCAAGTATTTT TGAGGTTGTTCCAGAGATGGAGTTAAGCTAATGAAGCTTAAACTTCAGGATCCCTCACTG AACTCCTTCTTAATTTATATATATATATATATATGTATAATTTTATATTTTAATGTTAAG TTGTTTTTCTTAAAGAGAAGTCACAGAATTGTACACATTTTATGTCCCACAAAGTCTGCA CTTGCCCCTGGGTGTGTTAGGAAAAAAGACAAATACAAATGAGAGTATCAAAAAATAGAA TTTAAACAGAAGATCCGAGAAAAAGAATAGAAAGAAAATAGGCCAAACATTAAATGCTAA ACAGTTTCCCCAGCTGAGCATCAAACTGAGCTCTGAGTTTCATGGAAGGCAAAGTGGTAA AAGGAATTTGTACATTGCCTAACTCTTGTTATAAGAATGTTGCATGTGTTCAAAGACAAT ATGTATTGTTAATATTAACAATTAATATCCATTAATCCTGAACTCTGAGAAATCTCAGTG GAACACTTTATAGGGGATAAAATCACCCTTTGACCAAAAAGTGATGTTTTCACAATGATA GTAAGTTTCATGGAAATAAGTAATAAATTTTCTGATCCAATATACATTGAGCAACTCTTA TGTCATCAGACATTGTCCCAGGCAGATCCAACAGGTGCAGAAGGGAACAAGACATGGAAC TTGTGCCCTCAGATCTGTCAGGCAAACACATTAAAAAAATGCAAAAACAAGTTGATAAAT TGATCATGGAGGCCTGTACAAAATGCTATGGGATCACAAAGGAGAGAGTAGCTAACTCAC ATCAGGGATGTGGAGGAGGAAGGAAATAAATAACTTCTGAGCTCAGTTTCAAAGGTAATA ATATTCTTTACATGGTAGTTGTCAATTCACAGAGAATGCTAAAAAACTGCCAACATGTGC CTAGACAGTTTTCCTAAGCACAGTCTGACTCTCATTCCTGTGGCTTTTAGACATAGTCAC TGTTTGTTGTAAGATGGAATTGCATTCATTGATTCATTCCTCACAAACCCCAAAGATACC CCAGCTTTCATGAAATAAATTGTTGCACTTCATTTCTAGCCCTTTCCGTCTTATCCCCTC AAGTGTTTGAGGAATTTCTCCTGGCTTACCTGTAGCCTTTCTAGTGGATTTATGAGTTTA TTCAATTCTTTATCTGTGGAGAACCACAAACAAGGTATTTGGACATTAAAATAAGAAGCA TTAGAAAAAAATAATGATATTTTAAAATATAGTAGTGGACATCCCTTGGTGTTCAGATAT TTTCAACTTCAAAGGTCTTTATTCAAATGAGCAGTTTAAAAATCTTTTCTAAGCAATTCC CATTTTACAGCAGAGGAATAGAAAAAATGACTCATCTGGCAGCACCTCAAAAAATTGTAA GCCACAAAATGAGGAACAGCCTGAATTTTAAGCAACCAATGTTAGGTAATAGAAAACATC TTAGTGAGAAAAACAGAATCTCCTAATAGCCTCGCTTGGTGAGGTTTGGAAACTTGGAAC AAACATTGCTCCCCTGCCCTGGTACTAAAGGAATGAAAAAATTTCTGCATCTTTCCAAAG TATTCAGCTGCAGCAAATACTGCATCAAACAGTCTTGCGGCTTTGTTTTTCATTGTATGG TGCCAAACACCCTGAGATCTCTGCCTTGCATAATGCCTGGCCTTCTAGCACCTTGTAAGT TTGTAAAGACATGAAAAGTCTCTTCCTGCCATCCCAACTTCCATTCTCTTTGATGGATTA CAACAGGCAAGCAGTGCGTTGCAATGGAGCAGGATTTTCAATCATGGAAAAATTTGGAAC TTCTGCAATTGATACTAAAATTATGATGCTGCCATCATATCTCACTCAACAGAGGATTTG CAAAAAAAAATAAAGATTCAGTATCAAGTCACTGTCACACTGCAGCAGAGGTAGTCTACT GAAGTGTCAGGTCAGGAATTCAGCAGTCCTTTGCAGAAATCACGTTCAGCTTGAAATTCA TAGGGTAGAGTTAAAACATGGACATGGAAATTTGGATTTCTAGTTTTGGTTGATCAGTAA TTAAGCTGAAGCACTACAAATTCTGAGCATTTAAAATCAAGATATTTTTTGTGTTTCTAA TAACTAAAATTAAGACTTCATTCTTTCCAGGGTTTAAAAGAATCAGAGTAAGTCTTAATT TCTTATTCTCTCCTACCCACTAAAAAATAGGAAAATAGTTTTAGGTTTTAAAGAATACAA AGCTAGAAATCTCCGAGCAAGCTAAAATGATTAGTTAAAATAAAACAAGGGCTGTTGTTC AAAGATAAATACTAAAATAGAACCTTAATGATTTTCACAGTTACCACCTGTTACTATACT TCAATGATGTGAAGAACAAGTCTGAACAACTCATTAACAGCTACCGTTTATTGGCCGCAC ACCATGTGTCAGACATTTTTATGGATTATCTCATTCGATCCTCACGGCAGCCCTATGCAG TAGATCTTATTAGCCCTTTTTCAGATGAGGAAACAGTGCAAAGAAGCTAGCAGACTTGCC TAAAATCACCCAGCAAGGCGGTATAAAGCAGAATTCTCACTGAGTTCTGTCTGCTTTCCA TCGCATGCTCTCCTACCCAAATTAGTGGTGAAGATGTAAATCTCTGGCTTTTAATTAACA GCATCTATCATAATGTTGCTTGGTGAATGAGCTATAACAATAATAGTAATCATCGCAAAG ATGGACCTAGTACATACTACCTGTCAAGCAATACTCTGAGTGATTTACATCTATCAGTTT ATATAACTCTTGCAGCAACCCTAAGAGGTAAAAAACTGAGCTACAGAGGGCATAAGCAAC TTGCCCCAAAGTCATGTGGTCAGTGAAAATTTAGGAGTTGGAGTCAAGCATCAGACTCAG AGAGCCTGGCTTCTGAGCCCAGACTATTGGCCACAGCACTATATTGCTGGGTTAGATACA GACTAAATTCATGTCCACATTTATACCAAGTCCAGCCATATTCTGAAATGGCTTCTCTAC CTTAGCACAACTTGTGAATTAAAGTGAAAGCTGAAAAATCGATGAAGTCCGTGATCAATA TGCACAACCTAATGTATTCTTGAATTATTCTGCTCAATTGAGTTTCTATTACAGAGTTTA ATCCACACATCTGACAAGTAAAAGAATAAAAATGATGGTTATATGAAATTAATCAAATAA AATGCCACGTGATTTTCAACAGCTAACACATGCATCTCATAACACATTTTAAAAGGTCTA TTGCATATGTGAATATATTTGCACGTGTCCATAGAGTGTATATTTGGTACTCTGTACCCA TAACTTAAGCCTGGTTTAATATCTAGTTTGAACCACCTACAAATGTTCATTAACCTTATA GGGAAACACAAAATGTTGGATGTCAAAAGCTTACTTGGACCAGATGCCGAAATGAGTATT AACTTCCCAACTCTGATGAGCCCAGGAGTTCTAGAATGAAACAAAATGGTTTCAATTGCT GGAAATTGTGTGTGTGTGTGTGTGTATAATGTGTATATGCATATATATGTGCACCTGTAT TTTGTGTGTGTGCTAATTTCTTAATAGTCTGAATATTATCAAGTGTCAAGTTTCTAAGAT TTTTATATTAAGTTAAAGATGTTATGTACTAATAAATAGCTAACAGCTTTTCTTTATTGT TTTCTTTTTCTCCAGGTATCCCCAGTATTTCCAGTATTGGTAGTAAGTAAAAACAAAAAC AAAAAAAACACCAAACCAAGTCTAGGCTAGCTTTGCTTTGTTGTTCACCTCCTCAGATCT ATTTTCCCAGTGTCCATTTCTGATGTAATAGGGTATTTTCTTTGTGAATTGCATTTTTGT GTTGGTTTTCTGCACAGATCTGGTGAGAACACAGATAAAGTGATTATTTGTGCATAACTC CATGAACATGGCAGTGCTATGACTTTTCTGACTACTCTTAACCAGTGAGGGCTACCTAGA CTCAGGTGCAATTCCTTAGATAATCATCATTCAGGAAAAATATAAGTAGTCCTATTTATC CATACTTAGCAACCAACAAACAAATTGAACTCTCTCTTAGACTGGATTTGGATGTCTGAC ATAATTTTAAAAAGCAGAAAATGAAAGCCAATGAATGCCTTGGGTATATGCATCAGAACC CAAGAAAAAGTCCATGATACCAAGGGAAGGGAATTTTGTTAATGCATTAAATTCTATGTT TTGTGAAGGCCTGAAACAGGCAAATTTGTGATCAGTAGTCTCTCTGGAGAGATAAAGGAA AAAGAGAATCTGTACATTCATTTCTCCTTCCTAAAATACGATGATCTATGTCTTCTTGAC TACTTAGCTTTGAGTTTGATATAGAAAGAGTATAAAAAATATGTGCAGAATTTGGGAGTG AGAGTACTAGAAATTCCTTTAATAAATCTGTTAGTATGAATCCAAGCAATTGAAGAGAAA CCGCTCTTCAACCATCTGTAGAACACTTCCCCAGTATCACTACAAAGAACTTTCTTCCAG CTATCATGGGAGAACCAGGTGTAGCTCCCGCTTCATGTGTAAAATAATGATGCCCTCATG CCAAGCCTGAAATTCACATTAAGAAAATGCCCAGTAACTTTACAGAGCAAAATTTTAAAT TTTTTTTTATACATTGCACCCTTTATCTCTAATGGCTAAAATCTTTGAACAACTACTAAG TAACTGATTACAAATAAATTACCGAGAAAGCAAGATTACGCATGGTAAGCGGAGAGAATT TTCACTGTAGTGTCATCCCCTCACAGGCTTGTGTCATAGGTGCTGTGCCAGGCAGGGTGA TCGCAGTGTAAATAGCCATTGAATGATTGCGATTCCCAGCATCCATCTAAAAAGCAATAC TCTGATAATTTGGATAAAGCAACTTCCTGCTTCTTATAAATGCACAGTCAGGTGTCCCAA TTTATAAATCAACCCAGTTTACTTGAGCTTGTGAATAGGCCTGGACACTGATTTGTTAAG CGCTAGATGTGGTAAATGCCATGAAAATTGGCCACTTTGTAAATAGAAGTAGTGTTCACA TCCATTTAGAGATACCAGCCTAATGCTACAGCATCCTCTTTGTGATCTTGTTGAAACAGC ATCAGTGTTAAAAACTTGCAAATGAAAACCTTCAGCTCTAATAGTCTAATTTTTCTGCTT TAGTATCCCCCTTGGCATTTGCCTAACTGTATATATACCCCACAATGTGCTCCTTTCAGG CCTTGACAATTGCATTTGCACGTGCATTTTAGTGCAACAGGGAAGCAAGTAGAAGCAAGC TGACACAGATTATTGAGGCTGCTATAGTGATCTGGCCTGTCAGAAGTTTCAGAAATGGAT GGATGGAAAAGTAGTTCTTTGGCGTTGGGGTGTCTTTCTGTTTGGAGTGTCAGTTGTATG TTGCATGGCCCCTCTAACTGTACTGCTCACTCGACATCCCATTCGGCCGCCTCCACCACA TTCCCCATATCTGAGCATCAGCAGATGTTGACCTTTTACACATCAAATCAGGAAATTTCT GTTTTGTTTTGTTTTGTTTTGTTTTGAAATCAGTGGTGACCTGAAAGGATGCTTCGTTGT GCCTTTGAAAAAAATATATTAACCTTTATTATCGAGAACCTAGGAAAATTTACTCCTAAT AAAAACCCTCTGACTAAAAGTGATATTTTGGACTCTCCCTTCAATATGCCTCTGGCTGTT CCGCTTAGAATGCAATGGGTATTTTCTCAGATTTCCAGCAAACAGGATGTAAGAGCTTCC AGAGGTCACCCAACATCACACATGACTAGCTTACCTGTTTCCTGGCTTTTAAGGTAAAGA GTTACAGTAAAACCATCAAACGTGATTGTATCTTCTAGGCTGCTTTAATGGCATTCGAAA GTTCCTTCTTTGTGGGCTTATAAGTTGCTTTTTGCGTGCACTCGTGGATTCCTTTCCCCT CCAAAGGGCAAGAATTCACACGTAGACGACACTGCCTGTTCCAGAGGGCACGGGAATGGG GTTTTCAAGGTGCAAGCCAGAGAAAAGGAAGCTGTTTGGATATTTAGCTAAGTTATGGGT GTTTGCCAGTGCTTTTTGCATTACCCCAAAGAAGGAATCAATGACTATAATTCCACTAAC TATATAGAAAGATACCATTATAGCAGATGTAACACCCCTGAGACCCCGATTATCACAGCA TAGCTCAAGGAAAATAAATGATGTATATTATCGATGTAGATTATTGATGTATATAACCAT CAGTTTACATACATATTCTGTATACACAGTGATTAAAGGTTTTGGGGCCCTAATAAATTT CAGTATAGATCTCAAAATGCCAACGCCTGTATTAAGGTTCAAATGCATGGATAGGGTGGT CATCCTTTCCGATCATCTGCTAAAAATGTTTTTGAAACAAATTTCCCATTAAGGTCATTC GTACCTGCTGTTGTCTATCTATTAACAAATAGGTTTCCCATAATCCTAAGGATACTTGAC TTAGAACTCAGTCATTCTGATCTGCTTTGGCCATGGCTGAAAAAATGCTGGTGATATTGT CAGCAATTAATGAATCCCAAAATAAATCTGTAGCCTTTGAGCCTTATGATCTATGTTTTC ACTTTACCTGATGTGGTAGGAATTCCTTCAGATTGCATTTTTTAATAAAGTGTATTATGC ACTTATAAGTAAAATTCGTGATTTTATCCAAGTGAATATTTGTTGCTGCCGATAATCCAA AGTAATAGTTGTCTTGGTGTGGGTGTTTTTGTTCAAGTGATAAACTGATCATTACCTTCT AATATATATCATATGATCTTTGGTCCTGAAAAGCAAATGATTACACAAATTATGTTAAAC ATTATATTATAAAAAGCATAATTAGACCAGCAAGAATTGGCCTAATGTGCAAATACATTT GTGTGGGTGATCATCACTTCTTACAAAACTGAATGACAGATGAGTCAGAGGTTAAAGTTA AGCTATCCACAAAACAAAGATCACATCAAGGAAGACCATTTCGAACTCTTGGAGTTTTGA AATAAATAGAATTTTTTAAATAACACAAACAAAAGAAGAGAGATGTACACATTTTGTGAA CCTGACTCTAGAGTATTTCCTTAAATTACTTTCAAATGACTGGCATGATGTTATATGAAG CATAGAATACTGAGGAAGGTGTTTGGCTATTCCTCTCCTGTCCCCCACCCTAACTTATTC AATTTAAAACAACAGTTCACTTAAGGGAAATAGCTAATTGTCCTGTTTTATCTTATAGTA AGCAGTGTCTTCATCACAGAGTTAAAAATTCATCTCTAATTTGATGTAATTGGCAAGACC ATTAAACAAGGGAAGTGCTACCTGCAGGGATCTGTCAGCCTGTTGAGGAAGCCCAGAGAT GTTTTCATACTTGAAAACATTTTATGCCAGTTGGAGACCTGGTAAAAGTTGTTTTCCATA CAGCATCCAAATATTTTTGTGCAGTCTTGATTTATTGTAGAAACCTGGATAGTCAAGAAA ATAACAAGGTTAATCATTTTCCCACCCAAGAGTTATTAATAATCGCATTCATGTTATACA GAGAGCTGCAGTGTTTGTTTGGGTTTTTTTTTCCCCTTTGCTTTAATACTTCTAAATCCC CCAAATAAAAGTTTCATTTGAATTGCCCTTTAACTAATTAGGTTTTATGTAATGAGGAAA AAATTATCAGGCTAGTGTAGCGATAGGCAAATTGCATGGTGTGCTACATTAATTTTGAAC TGTTTGCTGATGTTCTAGAAGGAAAGCTAAGGTCCCAGGTGAAATGCCTTTGGGACTATC ATGTACCCAGTATCCTCATCACAGAACCATTTCATATTTGTGTAAATGGCATTTCACATT CATGAAATCTTGTGGTTATCCTAAAATTGAATGAACATTAGGATATAGCTGCCTCTTTAA TCCTGAAGAACAAATCGAATATTCCAATGGAGGAGCTGAAATAATCTCCTACTTAAATGT CTTTTTAAAATCCAATAAGTTTGCCAATCTTTATTGACAACAATTGCCCACCTTGAGCAA ATTAACTTTATCATGTATTAGCATTTTCCCAGGTGACTTTACAATGTCAAGCCACTTTTT TTTTTTAAGTGTGAGCTGATATCTCTGCCTTTGCCAGTTATCTCTGTGGGGTCAGGAAAT TCGTAGCTTAAGCAAAAACTTGCCAAGATCTCCAAAAGGTTTCATTTGATGAGACTTTAG ACATGTTAACTATGAATTCCTGTACTGTGCCAGTTACTTCAAGGATGTGGCTATCAATTG AAGTCTTCTTGGACTATCAATGGAGAGCTGTCCAACTAACCATGCCACTGCCTAGGAAAA GTTATTGTAGGGAGGTATTCCCACATGTCTACAGAATTCTGTTTTACAAATGGTGAATCT GAGGTTTAGAGTGGCCACATAACTTGCCCAATGCAGTACAACCAGGAATGCCTATCTGGC TGCAAAGGCTACACTCATAACATTATACCAAGTGGAAGAGATTAGAAAAGAAAAATTGTA GATTAATTGCCTCCTACCCTAGATTTTTTCCAATCCATTACACTGTGCCTTAGAAGACCT GTTGATCCCTAATTGACCCATTTCTATGCAGGGAACTGTAGAGTCCTGGAGAAAAATCAG AGTTCATTTTCGGATTCCTTATTGTGTTGTCACCTGGAGAACTTACAAGCATGGTGTCTG AGGACAGGGATGGAGGACTGTGACCTCCCCCTTTCAAAATATACTATTCCTCTACCACCA AACATCTTCAATATATTGAGGAAGAGGGAAAATGTATAGATGTCAGGTATTTTATAGAAC ATGGAACAGTTTGTGAAATTAGCTATGCAAATTGTGAAGCATGCTTATGCCTACTCTGCG ACAGTAAACCAAAAATTTTTCTTCATCAGGATAGTTGCTTATAACAAAATAAAATTCGAT ATGCCATCTCAAGGATAACTCTGCCAGTATCACACTAAACTCTGTTTTCCCCATCTGTTT AATGATGGTGTGTTTCTGATAGTAGGTAGTTGCTGCGAAGATGGTAAGATTACCTCCAAG GCTCTGGGGATTTCTCCTGTAGAACTTTGGAGTTTCCTGTGGATTTCTTTTCTTTTCTTT TCTTTTCTGTTTTTTGTTTTGTTTTGTTCATTTTTTTTTTCATTTTTTTTTTCTGAGATG GAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGACGCAGTCTCAGCTTACTGCAAGCT CCACCTCCTGGGTTCACGCCATTCTCCCACCTCAGCCTCCTGAATAGCTGGGACTACAGG CTCCTGCCACCACACACGGCTAATTTTGTTTTTGGATTTTTAGTAGAGACGGGGTCTCAC CCTATTAGCCAGGATGGTCCTGTGGATTTCTTTCTGGGCATCAATAATGCTATTTCCATC CCAAGTGCGGTGTGTGCTTAAAAAATTTTTTTCAATTAAAAAAAATGCTATTTCCAGATT TCCTGAGGAATGACAGCAGTGACTGTATAAACCCAAAGGGACCTTGTAATTTTATCTCCA CCAGATAGTTTCCTCATATGCCAGGGAAGAAGAATGTTTAAGTAAGGTTCACTAACATCC TCACAGCAGTGGCACATCATATCATCGTGGTATCCTGTTTCTCACAGGTTGCCATATTTT AGAACCAAAAATTATGTAAGCATTAGTGTTGTTAGGAAACTTAATAAAAAAGCAACTCAT CCACCTCATCATTTTCCGACCAGGCAGCCAAGTCTTAAATGAATTCCCTAAAGCATCTAA ATAATGACAGAGCCAGAATTCCAGCTCAATGTCCAATTTCCAAACCAGGACTTTTTTCAT TCTACCATGACATTAGAATTGACCTTCTCATTTATATAAATTAAACTAAAATATGAGATA TTACATGGTAAACAATAATAGAAAAAAAATCAGAAAACTTTTTCCTTGATGGGAAAGTTA CATTTTACAATGTTCTTAAAGGCCATCCACAAAATGACTTGAAAGCTGCTCAGTAAATGC CATGTGTGATAGAAGACAACTTAATATTCTAAAGCAACTCTACCTCTAAAGCTTTCTTGA TGTTAATAAACTGTCTTTAGTTTTCTGTTTCAAGCTTGCTTTGCAGCTTGACTCACTGGG ACGTCAGCACTAGACAGTCAGGTTTAGCAATTCTATCATAGTTTTCTTCAACTTACAATG CAGTGAGCTTTCCTTGGGTGCAGAAGAGCAAAATATTTCCTTCCAGAGTCCAATTTTTAT AACCAAAATCTCCATTTTTCTCATTCATGAAAATTGATTTCAAGTGCGACCACTAAATTG TCATGTAACAGTTTGGGGGTGGGTTCTTAAAAAAATTGGAGAAACTACCTATTTGATTCA TATTCTAAGCTGATGTGGTTCTAAACCAAAAGAAATTTAGGAATTACCATTTTCAGATTA AAGGTTAGAAATCAAATATTGTCCACAGTATTACAAAATAATTTGTATTGCTTTCTGAAT AATAGTAATTGATAGAGGCCCTAGAATTGGATTATTCTCTAAATTAAGCTATATCTTAAG AGATCTTTTTAACTTATCAGATCACTTGGGTTAAGAACAATTAATACTGAAAAAAATAGG GGAAGACATTATTTTCCTACTTCGAGTCAGTAACTGTTTATAGTACAGCAATCTGATTTT TATTTACAACAGCAACCGCAAATAGAATGAGCTAACATTTACTGAATGCTCACTATGATG CCAAGCAAATATTAACTCATTCTGTCTTGACAACAATGAGTAGCAGACAGTGTCATTATC TATTCCATTTTGCAGATGAGAAAAGCTAGGCACAAAGCAGTTAAGGAATTGTTCAAGTGG TGGAACCGGACTTTTAACCCAGCCTGAGCTCTATTTACATGCACCATATCTTAAATAAAT TTATCCTAAATAGATTATTTTCTAGGCTTCCCACAGATACAATCTGAAAATTCAGACTAA TAATAGCAACTGAAAGGCATTTCAGATATTTTATTTTTTAAAGGAGGCAGTTGTGGAATA AATGATTTTGGTCTCCATACTACATATGTAGACATAGTCTTTGGAGCCTGATCAGGGAGA TCCTCAAGACAAATTCAGTCAATTTTAACAAAGGTATGGAACCAGCATCCTTAAGAAGAA GTGATTTCCATAAAAAGCTATTCTTGAATGATTTGCCATTTACAAGCATATCGTGATCCT TCCCCTCACCCTTATAATAATTTCTCAATTCAGTTTGGGTTTCACCAACAGTCAAAAGGT CCATAGTCAAGGCATGTAGGGATAATTTCCTCATCACACAAGGAATTCTTAATCCACTAG ATTCTCCAAATGGCATATGCCTCATACATACAGGCATCACCCTTCCATGAACTTTACTAT GATGCTGCTAGGCCATGAGAAAACCACTGGAGTGATGAAATTGTCAGCTGAGAGAAACCT TAGAAATCTCTTATCTGGCATTCCTGTTTTACAGATAAGGAAAGTAAAATCCGGAGAAAT TAACAGCCAGATAGCTCCTCAGTGGCGGAACGGGGATCAGACGTGTCATCTTCTGAATCC CAGTGCCCTTTGCCTTGTAACAAAACACCACTCTGAGACATTCATATTGACCCAAAGATT TTCCCTAGTTGATTTGTGAAAAAAAAATGAAATTAATACATTCCACAACAGTTCATACAA AGAAGCAATACAAATATTGTTGACGTATTATAATTCATTTCCATTGCTGAGAATTTTTCT CACTAAGAATTCTCAGAAGCTTCATGTTCTACAAAAACTTTCATTGGAATTGGATGTGAT AAGATAGAATTGCTCTCAGACATACTATTAAAGTAGCCTCTAATATGCTTAATTTACTTC TGGGAATTAAATGTTAGTAATATTTGTCGAGCATTTACTACATGCTAAGGTATTAGAATA AAAAGTAAAATTACTCAGAGAGTAATTGGCTAATTTTAAGTTGTTTTCTTACTTGGCCTT GCAATTATAAAACAAAATACATTTAAAAAATTAAGATGAGATATTAACTTAAAAAGTCTC GTGATGGCCAAATGTTAAAATGTATATGTGCAGTCGGTAACACACTATAGGAGTTTAGAG GCCACAAATTTCAATATCCATTTTTACAGGATAACATTTTTCCTCCCAAGGAAGGCAGAG CACATAAAATTTTGTCCCACTGGAGATATGTATGGATTTGATCCGGATTTTCATATGATG GCTGCTGGTGGTTCTGAGTTTTAGTAGTTTAACGAAGTTAGGCATTCTACATAATGAAAA TTATTTGAAAAAAAAAAGTCGAATTACATTCCTAGGCAAATACAAAGGCTTCCCCCACCC AAGAAAATATGTTAGATACACAATACAGAAGACAATTATATTCTCAGTAGGAACAGATTG TAAGTGAGGTGTCTATCTTGATAAGTCCATACAGTTCAAGAAGTCTCAGCAATTTGAAAG CAGAATGGCCTACATTAATTTTTTAAATACATATAAGAAGATCCATAAACTGGAACCTCA GCACCCTGTGGGAAAAAAATCATAAAACACTAAGAAAGGAGTTACACTAAAATACAGGCA CAGACAAATATTTAAAATATTAGTATATAAAATAAAGTTTAATTTATAGGGTTATTTTTC AGAACTCATTTCTAAAATTGATTTAATATAAAATTATTATCTTTACTTAAATTTCTTGGC AAAGCTCAATAACAAAATAATAAATCATACCAGTACTTGCATTTCATCAAGACAAACAAG TCACTACTTAACATTAAGCTTGCAAACATCACCTCCACTTAAGACCTATATTTGTTTCTG CACAGAAAAAGATGGAGAAAGCTAGTTAACCGAACTAAGATTGTCTTAATCTGATACTAA TAATACAAATACATTTTTATGTAAAACCACACCAATACTTTGAAAGCTTTATTAAATAAA ACAATTTCTGGGAATACAGACAATATTAATTTCCTCAAAACACAAATTTATAGTTTTTCA AAGCTGATCATCACAGATCAAGTAGGCTTGTCCTATTAATTCAATATCTACCATTCAATA TCTACCCATCATCAAAATGCTCAAGTGAAAAGCAACATTCAGTCAATTGACTTACATATT TTGCCTACATGTTACCAAATATGTATTTATTTAATAACACCTGAGTACAGATGTGGAAAA TTATTACATTCTTTCTTCATTCATAAATTTTCATAGATATCATCAAGATTGCCTTTGCCT TTGTGGATATATGTATGAGAACACAGCGAAAGAGAGCAACATTTCTGTTGGCTCTATCAG GTCAGCTTTTCTAACAAATATTTAAAAAAGCAAAGTTATAGTGCAAGTCTCTTGTCTTGG AAGAATGCGCTATAATCTAATTATGGAGGAAACAACATGATAATACCTGTTTACAGTAGC ATAGCCACTTGGTATCTATTTCTCAATTATCAGATATTTACTGAAGCCCTCTGCAAGGCT TTGCCCTTCTTCAAAGAGATCCAATCCAATTACAGAGATGAGAAATCGACCTATACAATT TTAACTGGCAATATTAAAACTCATGCCTGTCCACATATCGGTGAGAAAACAGGAACACTG GAAGTAACAGGTTACAGAAATTTAGAGCCAAGAGCCATCCTTATGGACCTGGGTGGTACC AAAGGACAACACAAGAGATGTGGTTTTGAGACTGGACTCAATAGATGGTAGGATTTTCAT CATAAAATAGCTGCTTTAATAGTCATGCCCATGCACCTTCACAAAAATAGTTTAAAAACA TTAAATCCTAGCCTGGCTCTTCTGCCTTCCATAACTGGAAGACACAAATAATACCAAGAT ATAAATAATACCAGTTCTTAAATTAATTAATGCTTTTATTTATTTCTGCATTGAAACCAA TAACTCTAGGAACATATTTTGAGGTAAAGGCATCATGAAAACACATACACACCCATACAA ACAAACCTTAAATACAACTGGAAGCATCTTGGACTTTTCTCCATAAGCCAAAACCACCAG TTTTCCCTCTTTCCTTTTCTGAGAAACTACACATATAAAAATAGGAAATATATCCACTCC TTTTCAGAGATAATGGCTCACACTTAAAACATACCCCGAAGAATCTATCATGAAAGACGA ATGCAACCAGTTCATATCTGTAAATATAAATTGAGGAGAATGGAATCCTCAGGTGAGAAA TTATTTCTTTAGTGTTATCTTCTAGTTTCAGGCACCAGCTTTACATAATGGTTTGGATTG CTGAAGTCCTTATTTGTATTTTTGTGTGTGTGTAAGAACACTCTACCTTATTTTAAAAGT AAATGTGTAGCTTTGGTAGGGAAGTAGCTATATATTTAATGTCCATTCAATGTTTTGGGA ATCATCAATTGCTTGCTCTTGTTTGATGTGGGAGTCATGTTTTGTTTAAGTGCATCACAG CCAAGTTAAAGAGCAGATGTGTGGTTTGTGTCTTTATCCATATAATTTTCTGTTTAGACC AAATGACATTATAGCTGAAAATAACATACCCTGATTTTTCCTGATGCGTGCAGATCCTCC AAAGTTTAATAGGATATGGCCGAATATTTCTTCCCTTGAGGTTTCTAACCCAAAACAAGG TAGGAGCATGTAAAATTCCTACGGACATAAAATCCCACATGTTTGGGGGAAAATCCTATA TGCCATTTTTAGCACAAAATAAGAGCATTATCATGAATGCTATGTCTTTGAAAGAATCAT AATTCAATCTTTTTTTCTAATATGAAGAGTGTCCCAAAAATATTAGAGTGAAAGATGAAG GGGAAAATTAGATGGCATGGAAGTTAAAAAGCCCTTTACCAGATTACATTGAAGGTCAGT CAGTCCCAGGAGAAGCCTAGACTTCTGTTACCACCACAGTGTGGAGGACAAACAAGACTT AAAAATGTGTGAGTGGCACAGGCATCCTTTCAATGTCTTCCTCTTATTTTTAAGTCAACC AACTGGTACCTCAGTTGTACTGAGGGTCTGGGTAAATACATAGAGGTAGTATTGTGACAC CTAACAGATCTGTTTTCGCTGACTATTGCTCCATATTGACTTGCAAAAATTTGGAGCAAT CTGTCTCTTTCCCTTCCTCCTTTTTCCTGTCTTCCTCCCTCCCTTTAGCCTCTCTCACAC ACCCTTTCTCACTCCCTGTCTCCTCTCTCCCTCTCCCCGCTACCTCCTCCCTCCTCTCTC TCTCTCTCTCTCTGTCTTTCACATCACAGTAAATTTTCCTTGTTGGAACTTTTCCTTTTA TCTTCTTTATCAATTAACATTCATGTGTTCCAGCATTTAGAGCAATCTGTTCTCTTTCTG TCCTTAGAGCAGTAATTATTTTCTGACTCCTAATGTCAAAGAAGAAAAAGAAAAAAGAAA AAAGAAAACAACACTGATAGACAGAAATGTGATTACGCAGGAAGAAAGAGAACTTTTAAA GGCTGAGCAATAAACTTCATAAGCTGCAGTGTAATGTTAAATTTATATTAACATCTAGCC TATAGATATATATAGTCATGTATAAATAGGAATTTATTTTAATATAGTATTGTATTATTT TGCCTTCTTCCTTCTTCAAAAAAAAAAAAAAGGCACATCTTTGGCTTCCACCTTCCTTAG CTATATACAGGATGTTCCTTTTAAACTCTAATGAATACAGATGGAAAAGGAAATGAGCAA AAGGAGGAACCAGGAAATAGCTGCTAAGCAAAACAAAATATATTAGTAATTTGTTGAGGA GTCAAATTGGAAGGGCTGCATTTTCAGTCCTTGATCAGAGTGATGAAATCTAGACTGTCC TAGATACATATATTACTAGCAAATAGAATTATCTTAATCATCTGCTCCAAATGAATTTTT TCAAGTTTCTGCATACATATATGAAAGAAGAAATACAGATCAAGCTTGCCCCTATTAGTA TAATTCTAGGAGGATTCAGAAGAGGTTTAGTGGCTTTATTCCTTGGCAAGTTCAATGACA GCATCTTCAGTGAAATGTCACTCAGTATTTCCTATTGAATTTCATAGTTCACAAATTATA CAACACAGGCTCTAAGACAACACTTCTCCACAGTGAGTTTTGAGCTGAACAAGATTATGC ATTGTTCAAAACCTGAAATAGGCCCATTTAATTATTTTGCTGTGCTGTCTGTGAGAGTCA CAGGACAAAACACTTTCAGAAATATCATTATGTAATACCAGTTGCACTTTCTTAGAATGT GGATAATGAGTTCAAATGAATCTATTGAGAAGCAGCACAGTTGAGCAAAGTTCTTAAATT CTGAAATTTTAGCGAAAGGTGCACTTTGTAGCAGAGGCCAGTTCTATGCAGCCATAATTT ATCTTGTCAGCATCTGCAAAGAACATCAGGCTCTGTTCTGTTTTGGCTATTTTCACAAGC AACTCTTCATGAATAATTGGAAAAGAAATGGCAGGCAAACATAGAGAGAAATCTCTGCCA TTAACAAGCTGATATCATCAAAAAGGTAACAAATGCTGAGAAGGCTACAACTTTTAAAGG TATATGTGTTCAAGATGACTCTGAGATAGGCCCAAATGCTGCTGAATGGCTGACTATTGG GACTGACTTATGTTCTAGGATGCCTAATTAGTTCAACAAAAATAGTCTAAATGGTGTATA TGTCGAATAGTTTATCATGACACAGAATGTCATGGTGAACCCAGGCAATGATAATGTCAA CTGACAAGACAACTCCTACTTTAAAAGATTGACAGTAGGGGATCCTACTATCCATATTGT TATGGTAACAATCCTTGCTTCACTGGATTCTTGATTTAAATGGTAATGATTTTTCCCTCT GAAAAGAAAACTTCTAAATTGTATTACTGACAATGTTGAACCATTTTCAGCCAAATACAA GCCTTACTTTGTGATTGAAACAAACTCCTAGAAACAACAGATACAAATAGTCTCTTAATT TAGGGCTACTTTTCAAGTGGGTTGGTGATAAGTTATTACAGTTTGAACGTTTCACTATTG TTTCTAATTTACTGTTCATTCTTTTAAACCTATCCAGTTGCTCCCAAATTAGCTTTGTCA ACAGTTTCTTCTGTTCAAGTTGCAAACCACAAGAGAGGTAGGAATTCTTGGATTCATACA GTGATTTCATGGTGTTATGTGTTGTGAAACATTGCACTGTATGAATCTGGAATATCTGTG AAGTGTACCCATCAGCTTATTGGTGAGGCATGTTGACTAATATCAATCAATGCATCGAAT AGTACTGAGAATCATCTGTAAGAAAAAAAAATGCTTCACTCAGAAACTTGACTGCAATTA AAAATGTTACATTTGTTTTCTGAAAGATTCATGTGTGAATAAGAATTACAATGGTTGAGG TTCCTGTTTAGAACACGAATGTTAGAGCACTATCATGGATACTCACTTGCATTGAAAATA AGGAAACCCACTTACAGTGAGTTTCAAGGATGCTTTTCATGAGACCAGAAAGGCAGGTTC CATGTATGGTGCCCATTTCACTTTGTGACAAATGAAACACCTTGGAATTTATGCTTCCAA AAAATTGTTTCGAATAACTTTGAAAAACACAAGTGAAGATCTGCACTGGATTAAGTGTTG CTTAGGATCCAAAAATAATAGTTATATTACTTTGTTTAAATGAAAGTGAGCAGCATCTCA TCTGTGACTCATGAATGGCCCATTCCAGCTAGCATCTGTCATTCACAGAATGAAGATTTT TCAGGAAACATGAAGACTTCTGTTTTTATTTCACCATTTTTTCTTTAAATGTCCTGTGTA ACAGGTGTGTCTTGTTTTCCACCCTTGACTGTTGGGCATATGTCACGTTTTAGTTTTGTT TTTTGTTTTTTCATAAAACACCTCTTACAAAGAAATGCATTTATTAATAAAATCTGAACT TAGTTTGACCCATTTGGTGAAAATGACCATAATGTTTTCCTATTCTTTATTGAATTTAGT CATTTCCTAGATTTTAATCAATGTTGAATTTGTCCTTCCATGGCATATAGAGAAAAAGTG GAAACTGGTCAGGAAATGGGAAAAGGGAAACCAAGAGTATTTAAACCATATGTCAAAATT TTCTCAAATGTGCTTTTAACCGTGGAACATAGAAGATGCCAATTTGGGTTGAGGGGAACC CAATTAGGTTTGAAATTTTTGGAAATAAGTCCTGTATGAGAAGAGCAGATGCAGGCTCAG AGGGTAACAAATCAATTTGGGTATGTGGTGTGTCATATAGGCAGTCACTGAAGCCATCAT AGGGATGCCATATGGAAAGAAACAAAGGAGGTGAAGGAGAAAGGAAGGAAAAAGCACATG CAAAGTTCATCTCTTTTCTGTCATGTCAAGCATGCTAGATATATAAGAGGCCTCTGAACC TGGAATTTGAACCTGCATCTCTAGTTTCTTGAGGACACAGCACCAATGAGGTCCAGACAC ATTCCTGGGGGCAGGGAGAAGCTACCCAATGAGGTAGACTTACCAGAGACAAATTCACAT CATCGTCAAATGATATGTGTGGAAGAGCTTCAACAGCTACATAAGGATGCAAGACAGGAT GGTGGGTGGGGAAAAGACAAGGAAAATGCTAGAGCCTCTTAATTCCCAGAATCACTCCAT TTAATGCAGTGAAGGGAAAATTCTTCTTAGAGTTCCAACTCCTTCACCTTTGAGGTCTTT TTCTCAAATTCTTTCTTTTTGAATGTCTAAAGTGAATTTTAATCAGCTCTGGATTTGAAT TAGCTTTCCTCATTTGGCCAAAAAAAAATCTACCTGTTCTAATTGTGCCACATTCATTGT ATTTTATGTTATATTTACAGAGACAATTTACTAATGTAATTATAGGCAACATGGGGAACA GTAAAAACGAGGATGCAAAGGAGAAATTGAATCCCCTCCTCTTAGTAACATTCTTTTTCT TTCATTCTCTGTGTCCAACCTCTTGATTTCCTGGAAATCTCATCTGCCCAGGTCTTCCCC AGCCAGTGTCAGTCAAAAGGAACCTTTTAAACCTTAGAGGGGACTTGGTCCTTTCCTTAT CTAGAAAGTCAACTTTGAACCCTTCCCCTTGTAAAACACCTCTAGCCTTCATTGCTCTTA ACTGTCTAGGTACTAAGTACTTTATCACAACTGCCTTCTATGTTTCAATATATCATATAT ATTACACATATATAGTATTTTTTCTATCTTCCCACTAGAAGAATAGTACTCAATGGGGAT GTGGGTGGATTTTGCCCCCCAGGGGACATTTGGCAATGTCTGGAGAAATTTTTGTTTGTC ACAGTTTGGGGGTTGCTACCACATCTAGTCATCTAGTCCGTAGAGGGCCCAGGGATGCAT CTGAAAAGCCTACAATGCACAGGACAGCCCCATACAACAAAGTTATTTGGCCCAAAATGG CAATCGTGCCAAGGTTGAGAAACCCCACACTAGACTCTGAAGGCCTGGATCGCATTCCCT TTGTCTTCTGGTACATGATGGCTGTACGTGGTACAGGGTAGTTCTCAATAAATATGTGTT GCCAATGGTTGCCATGCCACATTGTGTATACATACAGCTAAAGACCCCCTTTAGCTTTGC TTATACAACAGTAATAAAAGTTGTCTGAAATGCAATTTGACATTAAAAACTATATAAAAC CACAGCAATTTTCAGAAACCTGCTTTTTCTCTGCCTAAGCTGATCTGTTAATAGACATGT AGTGAACTCTCAGCTAAAATAATCACTAACTCAGCTGTAGCTTGTTCTGTGGCTACTGTT TTTCTAAACTCCTTAATATATAGGATATAGCCAGATTCTCTTCAGGAATTCAAACGATGA AGGAATGAATTTAAACATAACTTTTCTCTATCTTCCTCTGTTCCCCAAAGGAAGGGGTCT CAGGATCATCATTCATTCATTCATTTGACAATATTTTTTCAGTGCTTAGTGTATGCCAGG CAATATCTTAAGTTCTGTAGTTATAATTGTGCACAAAACAGACACAGTCTGCCCTTGAAT ATTTACACTCAGAGAGGGAGAAATTATTTTTGCATATACTTTTTGAATATTATAAATTCT ATGAAAAAATATAAACAAGATTAGGAAATTGAGGGATTAGGGAATGTGGGTGGGGCTATT ATCTCAGATTAAATGGTCAGAGAATTTTCTTTGAGAAGATATTTTAAAAAGAAATGGGGA AGCAAATAATGGAGATGTCTGGGGGTATTCCAGACCAGCAAGTGCAAAGGCCCTGGGAAG TGCTTGGTGTGTTTGAAGAGCAACATGGAGGCACTGTGCCATGAATTAGGAGGTGAGTGC TAGCAATGAGCCCCCAGGGAGGACAGGGGCCAGGTCACTAGAGAATGAATGAACTCCTCT TTTATTCTGAATAAGATGTGAAGCCATTAGAATGATGAGCAGAGGCATGTCATGACCTCA CTAAAGTTTTGAAAGAGTCACTCTGTCTGCTGTGTGGAGATGACATTATCACAAGGGTTG AGGCCAGAAGAACAGTTTGGGGATGATGGCAGTAATCCAAGTAAGGGCTGATGATGCGTC TGAGGAAAAGGTGGTAGAGATGGTGAGAGGTGTAGGCTAAGCAGTTGGAGGAATGGAATA GTCATGTAGTGAGATGGAGAAGCCTGGGTGAGTAGCAAGTTTAGGAAGGCAACCCAAGAG CTCAGTTTTGAACAAGTTAAAGTTGAAATGTTTATAAAACGTCCAAGTGGAAATTCTTGG AAGGCAGTGGCACACAATGGATGACTCTGAAGGGAGTCTCACTAATTAATTGGGGAGTCA GTCCACCCTGGAAATAACTATTTTGGAATGGCCTGCATATAGACCATGGGGTTGGGTAAA AATCATCTAGAGTGAATGTAGAGAACAAAGAGGTCCAAGGATTAAACCTTGAGACATTTG AAGAGATGAGGACAAAAAGCAAAAGAGAGAAAAAAGCAATGATGGGTAAGGAAGAAGAAG AATCAAGAGACTGTGGTGGCCCAGAAGCCCCTGCTTCAGGAAGGATTACCAGGCAGATCT GGGGACCCCATTGAGGTTTATGGTCATGAACTTCAAATGAGACTTGTTTCTAAATGGCTG GAGAAAAACTAGCCACATTTAGCTACTGGGATATGAGCATGAAGAGATGAAAAGTTGAAT TAAAAAAAAAAATTAGATTCAGGGGGTACATGTGCTTGTGTGTTTCATGGATATTACATG CATAATGGCCGGGGATTGGGCTTCTAGTATACTTATCACCTAAATATTGGATTTAGTAAT TACCAGTAGGTAATTTTTCAACCCTCAAACATCCCCCATTTTAGAGTGCTCACAGTCTAT TTTTTCCATCTTTATGTCCGTATGTACCCTTTATTTAACCCCCACTTATACATAAGAACA TGCAATATTTGATTCTCTGCTTCTCTGTTAGTTCACTTAGGATAATGGCCTGCAGCTCCA TCCATGTTGCTGCAAATGACATGATTTAATTCTTTCTTATGTCTGCATAGTATTTCATCA TGTATATGCACATTTTCTTTATTTAATCAACCATTGGTGGACACTTAGGATGGTTTCATG ACTTTGCTATCATACATAGTGCTGCAATAAACATATTACTGTAGTTGTCTTTTTTATATA ATGATTTATGTTCCTTTGGGTAGATACCCAGTAGTAGAATTGCTGGGTCAAATGACAGTT CTATTTTTAGTTCTTTGAGATATCTCCATACTGTTTCCCATGGAGCTTGATCTTATTTAC ATTCCCACCAACAGTATATGAGTATTCCTTTTTCTCTACATCCATGCCAGCATCTCTTGC TTTTTGACTTTTTAATTACAGTCATTTTGACTGGTGTAAGATGGCACGTTAGTGTGATTT TAATTTACATTTCTCTGTTGATTAGTGATACTGAGAATTTTTTCATGTGTTTGTTGGCTA CTTGTATGTCTTCTTTTGAGAAATGTCTGTTCATGCCTGTCCCAGTTTTTAATGGGGTTG TTTGTTTTATTCTTGTTGAGTTATCTGAGTTCCTTGTAGATTTTAAACATTGGTCTTTAG AGGCATAATTTCTAAATACTTCTCCCATTCTGTAGGTTGTCTGTTTATTCTGTTGATTAT TTATTTTGCTATGCAGAAGCTTTTTAGTTTAAGTCCCATTTTATTATTTTTGTTTTTGTT GTATTTGTTTTTTCGGTCTTCATTATAAATTCTTTGCCTAGGCTGATGTGCAAAAGAGTT TCTCCCAGGTTTTCTTCCAGGATTTCTATGGTTTCAGGTCTTATATGTAGGTCCTTAATC CATCTTGAGTTAATATTTGTATAGGGTGAGATAGAGGTTCAGTTTCATTTTTCTGCATAT TGCGAGCCAGTTTTCTCAGCACTGTTTATTGAATAGGGTGCTTTTCCCCATTGCTTAGTT TTGTCCACTTTATGGAAGGTCAGAGGTTGTAGGGTATGTGGCTTTATTGTTGGATTCTCT ATTCTCTTCCATTGATCTATGTGTCTATTTTTGTACCAGTACCATGCTGTTTCAGTTACT ATAGCCTTGTAGTATAATTTGAAGTCAGGAAATGTGATGCCTCTGGATTGGTTCCTTTTG CTTAGAAATGCTTTGGCTTTGGCTATTTGGGCTTTTTTTGGGGGGTGGGGTTCCATATGA ACTTCAGGATTGGTTTTTCTGATTCTGTGAAAAATGACATTGGAAATTTGATAGGAATTG CACTGAATTTTAGATTGCTTTGAGTAATGGGTGATTTTAACAATATTAATTCTTTCAACC CATGAACATGGGAAATTTTTTCATTAATTTGTGTTGTCTACAATTTCTCCTATCAGTGTT TTATAATTCTCCTTGTAGAGATGTTTCATCTCTTCTGTTAGCTGTATTCCTAGGTATTTT ATTTTATTTTGGGGGGCATGTAAATGGGATTGAGTTCTTAATTTGGTTTGCAGCTTGAAT ATTATTGGTGTATAGAAATGCTACTGATTTTTGTACATTGATTTTGTATCCTGAGACTTT GCTTAAGTCGGCAATCAGTCTAGGATTCTCCTACAGGATCTTTTGGCTTTTCTAGGTATA TGATCATGTTGTCAGCAAACAGAGATAATTTGATTTCCTCTTTTCCAATTTGAATGCCTT TTATTTCTTTCTCTTGCCTGATAGCTCTGGCTAGGACCTCCTGGAGAGTTGAATTTAACC AGCATCAACTTTTAACTGGGATCAAGATTTCCTTATAATTGGAGGGTGGAAGGCCAAGGG AGTATATAAAAGGAAGTGATTATAAGGATTGGACTATGGATACTATATAAGAAGAAATGG GAGGTCATGGGAGGTCAGTGATTTGAAGAATCAAATAATTATTAAACTATTAATATCATC CCTTCAGAAACTTAGTAGGATAATGCAACTCAAGCTGTACCTTAATAGGTTCTGTGCCTG TGTGGAAAGACCAGGTATTAAAAAGTAGGAAATTAACAGAACACCAGAAAATAATATAGC AGTTTAAGAGTCATATTTGAAATACTTTGCATTTATATAGTACTCTCATGTTTTTCAAAT CACTTTCAAAGATCTGTTTCTTATTTTATATTCTCAAATATATTATGGCCAGAGATGACA GCTTTATCAAAGTCTCAGAAGAGTACTAGAAGTCTTAAAAGAATCAAGTTATTATTACCC ATTTTCTACATCATAAAACATTTTAATGCTGATAAAACATTTAAAGTATCCAGTTATCAT TTGAAATAAATTTATACTATTGCATGTTTAGCTGAACATGATTTCTTATACAATTATTTA TCATTTCCTTTCTAAATTAATAAATTAGTTTTTAAACAAGACCCATAAATTGTTAATGTC CCCACAGAAATGTGTACTATTCATTAAATTCTAATAATAGTAGTGATAATATCACATTTA ACATTTTTATAGAGATTCATGGAATGGGTCTTAAACTGTTGAACTTGGGTATCTTACAGA TTTGGTTTTCTTACTCAGATAAAGTTTTATCAGGTAGATTAAAGCATGTAGTTCTGGCCA TTGGGCAGACTCTACAGAATCCTTTAGGTACCCACAAAGGAACCATAGTATGAAAAGTCA CCAGCCTTATTCTCTACATTTCCCTAACTTCATACCTTTGCCCACTCTTTACTCTATTAC TTTCACCTAAAATGCTCATTCCCTCCTATTTTGTTTTGTTTTAATAAACTCTACCTGCCC TGAGGAAGATTCAGAGTGCACATCCTGTAGGACATTTTTTCTAATTCTCCTCCTGTTAAA TGAAGTTCTCCTTCTACTTAGATTGCTTTATGTCACTGTTTTTTCTCTGCACATACTATT TTTTTCTGGTTATCTGAGCATATGTTTTCTTATTTACTAAATAAGCTTCCAGGCCACAAG CTTATATGTAGCTGTAGAAAGCTCCTAGATGAATTTTTGCACATAAAAGATGCTTTTGAA CAAAGCTCTATTAATTAAATTAGATGTACCAAGAACCAACCCGGGTTAGGGAACATGAAG AAGAACAGCCAATAAGAGACCTCTTCCAGAGGAGGCGACCCAGGGGCAGGGCTGTTATTG GCCCTCCTCAGGAATTCCAGGCAGTTCTCAAAAAGTCCTTGGGAAGCAATTAGGTTTGAG AATTGGGTTTCCTTCCTTCAACCACTGCTCTCAAAAGGCTCTAGTCCTGAAAGATTGTCT TTATTTCAAACTCTCAAACATAGAAGGCTCTAGAAGCTTTTCTGACTCCCTCAGAAGTCA GTAATGCCAGTATAAACAAGGCGTAACTCTGAGCGGTACAGAGGATTGGTGGGAAATGCT TGTTGTTTTACAAGAGATTTTAATTTAGTAATCTGTAACTCTATGATTATTGGTGGTAGT ATTATTATTCACTTGGCATGCCTTTACTACTAAATTTATATGGATATTTCCTTACACTGT CTCCTACATTGGAGTCTCAATGCCACCTTCTCCCAGTACTCTCCCTCTCCTCCATACTCG CCTCCCCTCTGACTTCTTCCTGTCCTCACACTCACCCTTCTCTCCCTGTTCACGTACACA TGGTGATACAGCTCACCTCAAATAAACGAAGTGGTTTGGCTTCAGCATCCCCCCTTTCTT CTTGCCTCTCTTTTAGCAACTGGGGTCCCGAAGTTGCTGACACTGTTTCTGGTTATCTTC TACTCTTCACCATTTGAGTATCCTCCTCTGCTTCTATCCAAATTTGATTTCATTCCATCA GGACCTTGTTATCAGCTTCCTATTGTAGTAACTAGCTCTCTAACAAATGAATATGAACTT TTCTGATGAGTGGTAGCATATTAATTTTTTTAAAAGTTTAAAAGTTAGCCACCTCTTATT ATTATTTACTTGACAACACTTACTCATTTTTACTCTACTCATCAAAATATAATATTTGAA AAATTTTATATAGGCCAAAATAGTAACTCAACACCTAGCCAAGTTCCTGACACATAGGTA GACCAACTCAATAAAAATATTTATTGAATGAATGAATGAAAGAATGAATGAATGTGTTCA AATAATGACTGTGCTTGGCTTTCTAGTGGGATAAAATAAAAGCAAGACAGATATTGATGC AAGAAATATTTTTAAACAAACAAAATTTGCAGTATCCTGGCTGACCTTCCTTATAAATGT CCAACTAGGCCTACCCTCATATTCCATGAAGACAAAACAGATACCCCACCTAGTTACCAC TCACACTTTTGTGATAATTATTTCTACCAACAGAGACTTTGTCATTATCATTTATTTTTA AAAGGTTGAATTGGATTTACAACTTCTTTCTCTAGTTGAGATGCAAGAAAGAAGAAATCT AGTCACCCTCCACCCTTCCCCAACTACTCTCATGCTCTTCTTCATCTCCCTGTCTAGTCA TTACCACCATCACTCCTAAGCCTCAGAGACACCTCTAACATTTCAGAGAAACCAAGGAAA AGAAAGGTGGGGTTACAGTAGCTACCTAATTCTTCTTTTGTAGCAAACTATTCTTGAAAC TTAAGAGAAAAGGAGGGAATCTTAAAAGCACCTTTTCGCACAAATTATCTCCCTGCTTTT TTTGTCTTCTCTCACACATATACATACAGATTTGGTCTGAAGAAAGGCTTAAGAAAGCCA TCTTCTCTTAGCATTGGGGAAAAACAAAAATAAAGAATTGTTTAGTTGTCTAGAACTCTA TTAAATTTGCCATGATGTATATGAAACCCCGACTGAGTTGCTGTCTTGGCATGATGTCAG AGAGCTAAAGGAGCCATGGTGATGGTACTTAGACTCTCAATGCTCACACAGTCCCCTCTC ACTTTTTTTAAGGCTGAAAAGATGAAAACAAGGGAAATGGTGCAAAGACACTAAAATTCT CCATCTGCAAAAAATAAAAATAATAGACTTTTTCATCACTAGAAACTGAGGCTTCCCAAA TTTTAAAAGGTGTACACCTGCAAATGCTTCTGTTCATTTTGTCTGCCAAGAATTAACAAT CTTCAGTCTTGTTCCGAATGTCCGACCTTTCTATCCTGCTTGAAACAGATGCTATTTCCG TGCCAGTCACAACCACCTGTTGCCACCATGTGTTGTGTTGAATCACATATATGTAATGCC ATTCCACCGTCTTTTCTCCATCCCTCATTTTACCCAAGCATGTAGTATGCTATTACTCTG CTACTGTATACACTCTGTATACATTTCTGTTCTTCCTTGCAAGATTGTGAATGCTTCGGC CACTCCAATCGATGCAGTTATATCGATCTGCTAAATACAGTCATTTGCGTGAGCTGTAAA CACAACACTAGAGGGCAGCACTGTGAGTTATGCAGGCTGGGCTACTTCAGAAATGCTTCT GCACAACTGGACGATGAGAATGTGTGCATAGGTCAGTTCCATTACAATTTCAGCTATTCT TCTGTGCCTTTTGAGCTACGGGGAGATATTTAGGGTGGAGAGGCTGGCGATTTGCACCGC GGTTGAGCCAGAATGAACTTTCTCAATGTAGAAAATATCCTATGGTAGATTTCACTTGTG ATTTCACTTGTATTGGTTGAAATCATAGTTGGGGGATATACTTTGAACCCTTATGTTGTT GCTTTAAATATGATGATCTCAGAAATCATGTTAAAGAAATTAAGAATTTTCTTTCTTCCC GTTTTTTGCTTTTGTATGAAATTGTAAAACCTGATGATTCTGAACTGATCTTATAGCCTT AAACTTAAGGCTATACATTCAACTTTCAAAATAGAAACTCATTATATGCGATTTAATTAT AGATATGAAAAATTAGGGTACAGATTCTTGCATATAATTGGTGATCAACGAGTATTGATA GATTGAAAATGTTGCTATTTGAGATTGAAAATGACTAGCAACTGGAAATGTAAAAGTTTG TCTGACTTCTTCATCCATAGCAATGAAATTCCATTTATTGAATTTTCCTACAGCTCCCAA AAAGGAGGAGTAATTTCTCAAAAGTATTCTAGGCAACTAATTATCTTAGCCCTGGAAAAC TGCGTCCACAGAGGCCCCTGAGCACTTTCCCTTCCCTCCCCACCAATGACTACTGCTCTT GGCACCTAGGGAGGACCAGGCACCTTTCCCACCCAGAAAATCTCCTACCTTTTACATAGT GAAACCTGTCTTTAAGAATATGGGGGTGCCAATGGAAAAATAAGAAACAATAAATGGAAT TTCACTTCATAATTCACTCTGAAGCAATGCATATATTTGAAATGCTGAAAAATATATGTG TAGCCATTACCACACCAGTAGGTAGCTATATAGGCACCCAGTTTTAAAGGTAGACTTTTT CACATTGAGGTACGTTCAATAGGATACACAAGCTGAATAATGACAAGCAATCTTTTTATC AAGAAAAGAAATCCAATTCGTATTTCTGTGATCATTGTCCTCTGATTGGATCGTCAAGAT CCAAGTGTCACAAAAAAAAGCTGTTGAGTTGTTTTTAATCAAATTGGGCCAAGTATATAT AATACTGTTGGTGTCTACAGTACTTTCTGTATTTCAGAGCATCTCCTTATTTATTATTTG TCAATTAGGAGAGAAAGTACTGGACTTAGAGGCCAGAAAGCTAGGCTCAAATTTCCGTTT GCTAGCTCATGGCTGTGTGCCATAGGTAAGTCATTTGAGCCTTCTAGTCAGAAAAGGATA AATGGGATGCACAGGAAACCCTTGGTCAACTGTGAACTGGCTTGCAGATGTCTTGTTTTG TTTTTACTTAATCCTCATTAACAAAACAGTGGGGTAAGTATTACACTAATTGTTTCCCCT GTCTTGTCATTGAGAAAAGTAAGGCAGATTGACCCAAATCTTACAGCAAAGGGTTTCTGA CTTCAAAGCTTAAACACTTTCAACCACTGACACAATTAGCAAAGCTAAGCTTGTCAGACT TTTACTTATGGTATGTGTTTTGGATGACAGCAGCAATTCCACTCTGAGTTTATGAACAGA AGTTCAATTGTCTTCATAACACTTGGGTTACAAAGATTTGAGGATATTAATGAAAACCAA AAGACATGTAGTTGTCTGAATTTTGAAGGCAGAGTACATTTTACTGAATGTCATTTATAA AAATATATAAATGTCATGCTATAGATAGGTAAACACCAGAAAAACTAAAATAAATAGGAA CACAGGATAAAAAACCTAACCATTTTTACATAAGATTAAAATGTTTTATAATATTTAATA TGATTTTAAATCAATCTAAAAAAGTCCTTAAAAGGAAATATTTTATTCCATAAAATTTCT CTTATCAGGTAACTTAACAATATCACAATATATTTTATTCAGAGTATTTTATTATTATGA AGTTTGGCCTTTTTTCCAGTTCTGAAGTAAACTGTGAACTCCACATCTGCTTCTTTCTAT CCAGTTTTAAGAGGTATAGTTCAGTTGTAAATCCATATTTGATTATCCACAGACTAGAAA ACAATCCATTCAGTGTCTGTCTTTTAAATCAGATAAACTACAGAAGAAATATGAAAAAGA TATCAATTTTGTATTTATTTTTACTTTTAAAAATCAAGAAGAGTTTTCCTCTCCATTTCT AGAAAGTTTATTAATTAAAATTATAAACTTTTGGAAAATTCCATTTTATCGAGGTAAACC TGTTTCTATTTAGTATTTTGTACTTGAAACCAAGCGAAGTACTTGGTGAACACAAAGGAG TGCATTCCTAGGTACTATTAAAGTTAGCTACATTAGGCCAGGTGCAATGGCTAATGCCTG TAATCCCAGCACTTTAGAAGGCCCGGGCAGGTGGATCACTTAAGGTCAGGAGTTTGAGAC CAGCCTGGCCAACATGGTGAAACCACATCTCTACTGAAAGAGATAAAAAATTAGCTGAGC GTGGTGGCCTGTGCCTGTAATCCCAGCTACTCAGAAGGCTGAGGCAGGAGAATCAGTTGA ACTCGAGAGGTAGAGGTTGCAGTGAGCTGAGAGAATAGCGCCACTGCACTCCAGCCTGGG CTACAGAGCGAGACTCCATCTCAAAAAATAAAATAAAATAAAAAGTAATATTAGCTAGAT TGTTCCCTCACCCACCATAATTTCTTAAATTATTGCCCTTTTCTAAAGAAGAAAATTGTG TTTCAAGAATGAATAGAAAAATTTAGCTAGCTGATAGGTACTAAGGTCTATCTTTTATCT GTAGTGCTTATATGCACACAATGAATTAATAACAATTTCCTTAAAAAGCTGTAGATTTCA CTTACCCTGCTTGAGGCGCTGAGGACAGTGGTACTGGGGCTGCCTGTGCACTAGGCTGGA GTTTGCCCTCTCAGGGCCGTTGGAAGCCTCTGGCTCCTTTGCTAAGGTTTGCCCTATGAG ACAGCATGAACCTATTTGCTATTTTCCACAATTAAGATTCCTAAAGGGCTTGCGGCAGGA CTGTTAAATTCGAAAGGATACATCACAAGTAATTGAGAGTTAATCTTAATACCATTTTGT ATAGAAAGCACTAATGAAAATGAAGGGATATTTACCCCATTCACTTTCACAGAATAAGGC ACTAATCTTGGAAACTTTGAACTTCATCTAAGTCTCATCTACATTAAAAATAAAAAAAGA ACACTTTGCCAATTCTTTAACAACTGACAATAAAATTCACCACCCTTGCTGTAAAGGAAC AACTCATATCTTTGACAAAATGTAGGCTCTGTGTGATGAAATAGATGTTGTAAAATACTT GCATCATTTTATATTATGGCAAATATAAAATGCAGCAGGCTATTCCATGTTGCCACAGTG ATTGCTGCTTTGTAATTACTGGTGAATTTGCCCATTTTTTCTACAAATTCCAAACACAGC CATGTCTCCAAAGATACATGTAATTACCCTGTAATGACATAGCAATTACATGAAGATGAC ATCCTTGCATGCTTCTGTTTCATGTAAACTTGAGCATTAAGCAGGAAGCTAGAGGATATA TGGTTTGTGACCCTGAGTAATCACTGTTAATAATCCAGCTGACAAGCTTTGCATCACAAT GAAACAGAGCTCAGCAGCTGCTGCTAAGCATTTCTTAAAATTATGATGTATAATTTTTAA TTCCCCTTTGAAACCCATGGTTGGGTAATCAGAGGTACCTTAAATAGAATAAGGGGAACA TAAGACACTTTTAATACCTGTAAATCAATTCTAGTATAACTTTTAAATGAAGCACCCCCT GCCAGGTATTTTACGTTGCTTTGTAATCTAACAGTCCTGCATGTTCTTCCTAATTTCATG GAATAAAATATGATCCTCCAAGACTCTTTGCATTACTCCAATATCCACCATTGACCATCA TTCCATAAATGACACTTTTAAAAAACTGAATTATTTGTTACATAAGGTGAAGGGAAGGCC ACACCCCTTCTTGTCCTTTATTTTCATGACTGCAAAACATTACACTTACCCACATTTTCC TATGACAATGACTGGGATATATTATGGTTTAAATGTTTTACTGTTTTGTTTAATTTTGTT TACATTTTTTGCCTCTAAAATCTTATATTAATTAATGGTCATGGGCTAATTGACTGGAGG AGTATGTGAATTCACGTTGGCCAGATGTAACTCTGCTTACTGGCTTACAAAACATTGGTG ATTTATTGTCAACTTACACACTTTAAACAGTAAAAAAAAAAATTACAGTTTCGATATAGG TACAAATTTATAATGTGCCTATGTACAGACAAACATTAAAAGCTTTCACAAAATTAGTAT TTTAAAATATTTTTAATCTGCTTCCATATACACATGCATATTAAAATAGAAAATGTTAAT TTAAAATAAAACTCTAGTTGTTAAGTACAAACTAAGCCAGGCAAGGAGAGAGCATTTTAG AGTTTATTAAGTTTTATTTTTACCTACATATATAACTATTCATCATATAAATGTTTGTTT TATAAGAATGCTGAACTCGAAACCTGACTTAATTAGCATAAAATAAATCATAATTCTAAG GTACTCCACATTTATTTGAAGAATAATTAGTGTCTGTGACATAAACTTAGAATCAAACCC CTAGACCCATCTATAAGGCTAAACCCTGAATCCCCATAGCAAATCTAATATGCCAAACTT GATTATATTAAACTAAATTTTCAAGACTTCTCTTGGTTAGTTGGATGGTATAGTTTTATT TGGTTTTTCATGAGGGAACTGCTTAATGTACCCATTTTTAAATAATGGAAACTGAGAGGC ACAATAACTTCCTCAAAAGTATTAGAAGAGTAATGAGGAAAGAAACTTTAGCTCACAGTA CCCAAAAGCTGCCAGCTACCTGCACTATCTTTCCAGCTAATAGAAGCCTAAAGGATATCC ATTTCTGGTTCAAGCTTTAAGCAAAATAGAGCTTCAGAAGTAAAAATATCCTATATAAGA ATGTGTGAGGAATCAAGAAAACACTGTATTCACCTTTTATTGTGCAAAGCTGTATTGTCC TGCCAGCAGACATTATAATGAAAAATATACATCTTAAATTATAACTATGTTGAAAATTAT TTGGGGTTACAAAGTTTATTTTTCTTTCATGATTGTTAAGCTGGGCTGCATAAAAGCTGC ATTAATATGCCTAGCAAATACAACATCTAAAGGCTTATCACAAAATGGTATATGCATGAA TAAGTTAAGATGCTGTCCCAAATCATAAAGTAAAACTACCTTTGAATGAGCAAAGTGCAT TCATATTGTACTTTTAAAATGTTCAGCAGTTCTCAAATATTGAGTGCAATGGCTAAGCCC ATTTGAATAATTTAAAACACATTTTACACTGATGGCATATTGATTTATCCTTGATATACA AACTTCTCATGGTGTTTATTAAACCATCTAAAAATATCCTAACAAATGGAATCTCCATTA CGATCTGTTACCAGTGAAAAGCATGTCTTATTTCCTTGGAAGTTTTCAGTTGATTTCCTC CCATATCATAAAAATGATATCATGGAAGGCTAAGCGAATAAATAAATGGTTGTGAAATAG CCATATTTGCCGAAGCATTTCATTAATGGACATCTTTCTTTAAGTAAGTGATGCATTTAA GTACGTGACGCTCCTGTGTTGATAACCTGTAAGCCATGCAGACTTGTCTCCAGCCTGTGT GTTGTCTTGTTTCTACAGAGTGTTATTGTAACCCTTTGGGCTCAATCCATGATCGTTGTA ATGGCTCAGGATTTTGTGAGTGTAAGACTGGAACAACAGGGCCTAAGTGTGATGAGTGTC TGCCGGGAAATTCCTGGCACTACGGCTGTCAACGTAAGTAACTCTGGGAGCTGCCCTCTG CCTGCTGCAGCATGGCTGATTTCTGCTTGGCTAGGCCGGTGCGTGCAGCTTCTCAGAGCA GAAAAAGATCCAAACCGCTGACAAGTTTTAAAAGCTACTTAATGCTGCGGCCAATGTATT GGGAGAGCAATCCATCAGCTGTCCAACTGGCTTTTTTGAAGCCCATCTTCATCCCCTCAG TTAGCTGGAGCAACTTATATTGAAATATTGTATGGAGATCCATATACCCGTCCAGACCAT AAATTAAGTGACACAATAGGGACCCAGCGTGGAAATCTTCACCGCAGAATGAAGGGTGAT GTGCATGTGATTAATATATTTCTTGAACTGAAAGTTACCCTAGAGCTCCAGAGTTCATAA ATTAAATGATATCTACATAACTTATTACTACCCTTGCTATCATACCCATCACTGAATCTT AACCAAAAACCTAAAGGTAATAAATCTAAGGAATATTTAAACGTGGGGTAAAATAAATGG CAAAAATCGATATTGATTTTAAGCCTCTGAGGTTAGGCACTATGCGAGGAGCTGTGGACA AATGCCATTTGGTTCAGCCTCATTTCTCTTGAGATTACCAGGTCTTCAAAGCTTGTCAAG GCACGTGGCATGTCAGTGTGTACAAGGAACATGAATTATAAAATCAAGGCAGAAGGTTCC TTCCGTCTTTTATAACCTTTTCTGCTTTTGAATTCCGAACTAACTTTCCATTTCATCTAT AGACAGGTATTTTGCTAGTATTAAAGCACCACAAGACATATCCTGTGTAGCAGTGTGGTC CAATAGAAAATCAAGCAAGCCACATATGTAATTTTAGATGCTTTTGCTTTCCACATTAAA AAAGTAAAAAGAAATAAGATAAATTAATTTTAATAACTATTATATTTAGCTCAAATTATA TAAGATACTATTATTTCAACATATAACTAATATCAAAATTATTAAGGCTATATTTTTCGT GTTTTTTTATTGTCTTTGAAGTCAGATGTGCATTTTATACTTGCAGAAAATGTCAGTTAG GGCTGCCCATATTGTAAGGCTTAATAGCCACATGTGTCTACCATATTGGACAGCACAGCC CTAGAGTTATTTTTGCTTGCTTTTCACTTGAAACAAATGTCAGCATGCAGGAAACATCTA AAGCCAATTTCTATAGAAAACTGTATATTATTTGTATAATATAGTAGTAATAGCAACTTT TATATTCTATAAAATAAATTCTTCATGATGAATTCTATAATAATAACTGTGTAGATCCAA TTTCTATACAATATTATAGAATGTTCTATCTGTTACTTATGGAATACATAGTTATCTGGC AGCCACACTTCTAAGTAATATAACTCCAAAGTGAAATGCCATGGGCAGCAATGAGCTCTG GCAATAGGTTGAAATTTTGGCATTGAGCAGGCCAAGGTTAGAATGGAATCCAAGAACTGG GAACTGAGGTCTCCAGCCTTGCTGGAGAGGAACACTGAAAGACAGTCAAATAGTCAGAAG TCAGGCCTCACACCTGTATATAAGGTCTAGATAAAGCCATGGTTTAAAAGTCTTGCATGC TGTTGTTTTCCAGAAAGTGCTAGTCCTTAGTGCCTGGGAGAGTTGGTGGATCCCAGCAAC CATGTGAAGTGTCAGGGCTCAGAGTGAAGCTATCAATCATGGCACAGCTAGACCTCAAGG CCTAGAGCAGGCCAACAGTCAGGAGAAGAGGAGAATAGGCAGAGGAAAAATCAAAACCAG CACCAAGACTCAAGGCATAAAGAATAAGGAGACTTTGTAATTAAGACACACTTCTCAAAG AGAAGATCTCATATAAAGCTCCTGAGGAAGCAGGACCTAAAGAATGGGTTGCTGGAGTGT ACTCAGGGTAAGACTTGGGAGAGGAAAATAAGTCAATCCTGCTTTGGGAAAATGCATCTC AAAAAGGACCTAACCCAATTTTTCTATATTCATTATTGGAGTATTATAAAAAATATGGTG TTGCCACCAACTTTTCCCTTCTGGAATCAAAAGACTGAATTTAAGCCTTACCCTGCCACA TACAAATCATAAAACCCTCTGTGCCTCAGTTCCAGAACCTCACATACTTGTTAGGTGGAT CACTGAGATGATGAGAGGACATGCATTTATTCTTTTGAGTATGTATTGAGTACCTACCGT GACTTAGGCACTGGGCTAATGGTAGGGCACAGAAGGATGAAAAGAGAGAGCTACTGTGGA CATGTGGACATGGAGTTCACATCCGAATGAGAGGCCCAACAATTACGATAGAAGGTAATC AGAGCTCAATAAGAGGAATGTACATGTTATTTGTTAGTGAAGCCCAACATGGGGAGTAAG TCTTCCCAGAAAAGTGACATGTAGTTAAGCACTAAAGGATCAGTGGAGCTTTCCAGGATA GGAATCTTGGGTAAACGTGATTGAGCTAACACACTGTGTTCCAGAACTTGCGTGTGTGTG TGTGTGTGTGTGTGTGTGTGAGCATGCACATGTGTTGGGAGTAAGGGAAGATGTTAAACA GCATCCAGGGACTAGATTATGTGGTTTCATGAATCCCAAGCTAAGACATTTTATGTTGTC AGGGAGGAAAATCGGAATCATCATCTGGAGAAGATATGTGATCCATCATATGGTTTTAAG CAGAGACATGAAAGGAACAGATTTGTTTTTAAAAAGATTATTCTAGCTACTAAGTAAAGA AAAGAATGGAATGGGTTGAAATTAGATTTGATATATAAATTTAACATCGTCCAAACACAC CTTTGGGAACATAGGAGATTTTTCTCACTCTGAAATCTTTGTTCCTTCTCTTAGACCCAC CCACATAGGGCTGGTATTCTATGTTAAAATATAGAAATTCTTCTGTCAGTTAGTAAATGG CTACTTCACCAAGATCCTGAAGTGCCTTCCCCTGGGATCTCTTGGGCTGTCACCAAGGAT CAGCAATAACGGGGTAACACGTGTCACAGTAGCATGCCACTAGCACCTGCTCCAGGATTA TAGTTGATGTGCATTCTGATTAGTTGGTGCTGGAAGGTTGATAATTTTTTTTTTTCATTT TGCTCCTGTCCTCACACACATGAATGCACTCAAAAATGCCCCTTGAGTGCATCCTTGTCT TCCTTTCCCCTCTTCCACTGCTCACCCTGACTTCCACTTGCCCTGAGTGGAACCCATCCT TGGATTTGGCCACAGTATTAGTAGAAGAGCTATTAACCTGGCAACACAAAATCAATGCCA AGCAGAAAACCAGTGGGAGAGTAGGGCTGACAGTGGTGTTGCAGTGATGAGCTGAGAGTA AGCAGGCATTTAGGTAGGCACTGCCAGGGAGGCAGTAGGAGATATCAGGAAGAGTCCAAG GGATCCAGGCCCAAGGTTCCAGTCCTCCCAGAGGATTGTCAAAAGGAGCCATGTGGAATT GTGGTCCAAAAGGACTTGGGTTTGGGAACAGAAGATTTAAAAAAGGGATTCAGTAACTGA CAGTGTTGCCTATATTCTGTGAATAGAAACAGTGAATATGCTCTTTGAGTAGACTCTGGA TTCGTAGAGACCAGGGTCTGAATCCCTTCTCCACTTCTTATGACCTGCAAGACTAAGAGG AAATTACTTGGCCCGTCTAAGCCTGGTGTTTCATCTAAAATGGGGTAATAATATGACCTA CCATATATAGTAATTGTGAAGGTTCAAATAAAATAATGAATGTGGACCTCGTAGTACATA GTAAGTGCTCAATTATTATTACTACTTCCAAGCACATGTTGATATGCCATAGAACTAAGC AAGAATCCATGTTCAAAAGCTTTCGTGCAATGTTACTGTAGAACTTGTTGGGCCACTATT GAGGAATCAAACTGTTGACCTGGGGGCTTCTAAAAAGCCTCCTGGTTAGAGACAAGACGG ATTCAAGAAAGTGAAGCAAAGCTGACCCCAAAGCAATTATGGGGTTTGAGCTGGGGACAT TTTAAAAACTCCAGGCTCATCAGCAAACTTTCTGCTTGAGAGGCCACCAATTATGTACTG TGTAAATGTAGGCAAGTCTTTCTGAATTAAAAGGTGAAACACTTCTAAACCACTAGAATG AATGGTCTTTAGACAGCATAGAACAAATAACCTAGGAAAGAAAACAGAAATAATAAGATT TCAAGCAGGCCTGGCAGAATCAAAATTAGTGTTGAGGTTACCCAATAGAAAAATGAGACA TTGGAAAGAAAGAGAAAAAAAGTTTTAAATGATCCTTTTGAAACCAGAGAAGAGTCAACA GCTAGGTTCCAGAGAATAAAATTGAGCCTTCTACATAGGAAGCAGCATTCCATGCTTTAT ATAAAATATGAAGGGTTAACATGTATTGGGAAGTAACTAAATAGTTGTTATCAGCGCCAA AGTAACTGGACGTAAAGGAGATTTATGACTTTTCAGTTTGGGAGGTAGAAATAGCCACTT GTAGAACTAATGTGACTGGTGAGGAGATATGTTTGTCTTCCTGGAGGATGTATGTAAGAC ACATGGGAATATGCTGCAGGGTTTATTAAATCCACCAATTGTTAACTTGTGTGAATACTA ATGGTACTTTCAGAAGAATTCATAGTCTGCTTATTTAAGTGAAAGTCAAAAGATTTGGTG ATATCAGTTAAATGTTATGATTTTGGAAGATGCTAGAGCTGTAGGAAATAAAAAGCAAAG TACACATAGCAAGGGGGAGACAGATCACATCCTTTTCTGAGCGCAAGTGGGAAAGGCTTT CCATTTTTAAGGAACCATGTGAATAGATTGGGCCCACACATGTAATCTAGGATAATCTCT CCTTTTCAAGATCTTTAATTTAATCACATCTATAAAGTCTCTTTTGCCAAGTGAGGTAAG AGGCTCTGGGGATCAGGATGTAGACATCTTTGAGAACACATTATATTGTGCTTATCATAA TAATAATAAAGAATGTCAAAGTTTCATGTCAGAGATAAATATGCAGGTGTTATGAAGACA GAATGCAACTCATGCTGGGGAAAAAGATATGCAATGATAAAACATATTCAAAAGAAATAT TTAAAAGGATTCGAGAGGAGTAATGTATGTCAAGCAGGTATAGATGTGCATTGTGCATTA CAGGGTAGAGATAGTGAAATATGTTTCAATCAAGACCACAGACTGTATAAGAAAGGTATT GTGAGAGCATATTGTAGACCACTAGACCATTTAGAGGATACATTGTTCAGAGGAAAATTG GAAAATTTAAACATTCTATCTTCCAAAATGGGGGAATTCAAATATCAGGAGTTCTGCTAA AAGATTTGTTCTGGTAAAATAGTTTACTTGCATTAATGAGAATTTCTTTACCCAAAAGAG TGGAAGAAGCAGTCTGAGGAGCTACCACTTATTGGTACCATGGAGAAGGCATTGTCACAT AAGGGAGCAAACACTATTAAAAATCTAAGAGGTATTGTTCCAAACATTAAGAAAAATTCA AAATATTCCTGGGGGAAAAAGGTAGGATGTTAGACCTTTTTAAAAATGGGTGTTCACATA TGCACATACACATACAATCACTTTTATTAAAAATAAAAGCATAAATTGTTCCCAATAGAC TACCTATAAAAAAAAGAGAGACCTCTACATTAACCAACTTGACTATCAAACGCTCTTTCT TCTGAGGTTTTGATGAACATTATTTCAGTCCCTACACTGTGTTGCAAATTTAGGCTAAAT AATTTGCAAAAATGCAGATGGTATAAGGCTGTGCTGACATAGTTCAAATGACAAAAATGT AAAGATATTAGCTTACATTAAAGCTCAATTTTAGACAGTATATTATATAAGTGGCAAAGG AACTAACAATTTCAGGCTGAACAAAGATCAAAGGAGGTTATAGTCCCACTAAAACATGTC CTGAGCAGCCCACATCAAGGGGCCAGTTCTTGGAAAGAGCATTCTAGCATTGCAGACAGT GATGTAAGAGAGTCCCTTCTTTGATGAAAGTTTTTTCATATGAAGCAGCTTGATAACATA TGTTACAGATGTCAGCCAGTGTTTGGAGGGCTAACAAGTAGACATGGTTCAGGAAGATAG AACAGGGACCATGAATAATGGAGATGGGTTTCAATTTAGCATTTTCCAACAGTTACGCTT TCTAGGTGTCTGAGAATATAGTAGGTGCATTGAGTAATGACAACTTCCCCAGACTCTGGA GAAGTTCCAATAGAAGCTGAACAGGCTCCTATCAGTGACGCTTTCTGGAGAGTTTTGGCT TAAACGAGAAATTGAGTGAAAACTCTTTAGGGCCTCTTCAACTTCCCAGCTTTAACGTCA GACCACACTCATGCAGCAGAGGGGAGGCATCGTGAAGTTGCCCACCTCAGTTTATAGTAA GAACCACAGTTTGATCACTTGGCTGTCCTCTACACTCTAATCTTTCTTTACCCACAGACC TCAGACTCTCATACTTCCCACTAACCGTGTTCTCAGTCCTCACTTCTGGTTTCCAAAAGT CAGAAACTAGAGACTTAAATAACTCCTTTTATTCTAGGGATTAATTGGTTCCTATCAAAC TCTTCTATTACTATAGTTCAGGAGGTTTTCTTTTTTTCTTTTTGGAGGGGATAGGGGATT AACTACTACAGTCCTGACGAATTGTGATCATGAAGGTATTAAGATGATGCTTCCAATTGC CTCTGTGAGATGAAGATTATACCTCCCTGGACAAATATCTTGCGCCTAACTTGTAATTTT TCAATGTTTCTAGTTGCTGTCTCTTCCTATTTGTCGTGTTACATTAAAATGTCCAGTTCA CATTTCACCAGTTGACCTCACACTTTGAATTCATTGACAGGCAGCATGTCACTTAAACAA GGATGTGTCTGTGATGCTGCAGAGCATCTGTAGTTGCTAAACATATGATTTCCCTCATTT GGCCCTCACATGTCTATCAATCTCTATCACTACAAGTTGGTCTCATCAATAAAATGAATG GCATCACTGAATCCAAGTTTTTAATTTCCTTAGTATCATTAGTTTCCAATAGCACCTTGA ACACAGCATCATTTCCCTTGCTACATACATAAGGGTGATGAAAAATAAATAGAGAGAGGC ACTTGATGTTACTGTGGTACGACTCCTAAGGGTGGGAAGGAAGTGCTCTTTAAACAGAAC CAGTAGGAGCCTCCCAGAGGCAATTTAAAAAGGAAAATATTAGGAAGACAGGAAATAGAA AGTGGCAATTTGTAGGCATTACAAATAAGCTGGTAGTACTCCTGGGGGCAAAAAGGATCG TTTTGTCTGCTAGATGAGCAAACCCCAGGGTTGCCCCCAGTTGTGAAGTATCTCTTGATT CAGCAGGAAGATGCCACACCACTCAGTCTTGCTAATAGCCATTGCATTCCAGATGCAGCT CTTATTTTCCCTTGATTCTTAATGTAAAAAGCCCATAGACCTCTAAAACATCAGGGACCT GATGCTACCTCTGAGCATGCAGAGTCAGGGCTTATGCTGTGGAAAGGACTTTAACTCTTC ACACACTAAGGGCTCCATTCAGAGCAACCACAAAAGGGATACACTGATGGAGCTGGCTTG AAAGCAGTGAGTTGTTCTGAATGTACTCCACAGTAGCATCATATCCTAAATACATTCAAA ACCCACAGCTCCTGAATTGCTGAAGCTTAGCCTAGGGCAAATGCAGACAGTGGACATACC AGACGGCAATTCCAGGCACCCACTGGCATTCTGAGGCTTGCCTACTATTTAGCCATCCTG TGCTCAGCTCAGAGAGGGGCCTCCACTTTGACCTGGATGGCAACTTTTCATATTTACTTG ACAATCCATGTTAATTTCCCCCTTTATTTAAAGAGAATATTGAGAAGGACATGTATGCTC AAACTCCACAATTTCACACCGCAGAACCACTGAAGCTTAACAGTGAAAGGTGTATGAAAT GCTGGTGCTCATGGAAAAATGCAGGCACAGTTTTATCTGCTAGCAGCCGAGAATCAAAGC AACAGCCTGATCCTACCTGATAATAAGATGATAAGAAGGCCAAGTGGTAATACAATATGT GAAGCTCTTTTCTTACGTAAGTACATAAGTGGAGTTTCACCTTGGGCCATTCTTTACACA CTAATGAGTGTATGTGTGAGTGTGTATGTAAGAAAAAATTTCAAAATTTTCTAAAGCTAC ATATATAAAGATAATGTCTAAATGTGAAAATCAGCCCAATTGCAAAAGGGCCATCCTACT TGAAACTTGCAGAATAAATATTTCAGTTAAGCAAGGGCAAGTTCTCAGCCCCCAGCGGAA CAGAATTCTGGGGAAGAGGAGTCACAGATAGACTATGATGAGAGGGTTCTTGAAAACTAA ATTGTAGGAGTCAACACAGTGAGGTGAAAGGAAGCCTTAGATTTGGAGTCGGGGTCTTGT TCTAGGTGTAACTCCACCACCTCTCCAAAGAATGTTTGCTCAATCATCAGCCTTTGAATT TCCTTCTGTGAAATCCTAGAGAGGGCTTGGATATTCCAAGGTTCCTTCTTGGTCTGAAAT TCTGTGATCCTGAAATCTTACAAATGGTCCCATCAGTTTACATATGGACTTATTTCTAGT AAAGAATTATTATTATTTTAAAATAATAAAAAGTGTTACTTACTGAGCCCTTTGTATGTG TCGGGAACATGTATGCATTATCTCATTCCACAGGAGAAGATTATTTTCCTTATTTTATAG ATGACAAAACTGAGATTTAAAGAGGATAATTCCACCAACTCAAATACCTGTTAAGTAGCA CACCAGTTATTAGTGAATATTTATTGTTAATCAAATGGCATTTTATAGGATTTTGTCACT TTTACTTTGCAGATGGAGACAGAAGCTTTGATAATTTATTCCAGGGGTCAGCAAATTCTT TCTGTAATGGGCCAGATGGCAACAATTTTAGGCTCTGTAGGCCATACAGTCTCTGTCACA GCTACTCAACCCTGCTATTGTACTGCCATAGACAACGCTTAAATGAAAGAGTGTAGCTGT GTTCCGGTAAAACTTTTTTTATGGATGCTGAAATTTGAATTTCATGTAATTTTCATGTGC CAAGAAATATTCTTCTTTTGATTTTGTTTCAATCATTTAAAAAAGGTAAAAACCATTCTT AGTTCATAGGCCATTGTAAACAGGAAGCAGGCTGGATTTGGCTTGCAGATCATAGTTTGA TTTATTCCAAACTCAAACAGCAATTCAAGATGAAGAAACAGAGGACCAGTTAAATAAAGA ATGTGAAGCAGAAGGCAGGAAAGAACATAAGAAAAACATACATTTCATTAAAATGTGTCC TCTGTCTTGACATGGGTATCACAGGGAGTTGAACTAACTGGTTCTTATTTACAAGGCCCC AACTGTTCTTAAGAAAAATGTTAGGGTTCCCAGAAACATAAGGGCTTTGACCATATCATT TCCAGGACAAGATCACAGACATAATCAGTGCCGTCTGTTTAAAGGCTTTAAGAGCCAGCT GAGCCAATTTAGCATCAATTTAGTACAATCAGCAACTAATGAAAGAGAAGTCAGGGTGGC CATAAAATGATCAGGATTGCTCATGTTGGTGTAAGGGATCATTCAGTTGTATTCTGCAGG AACAACCCGTCATCTTGAATATCAGCAAAAAGCTCTATTTAGAGACAATTACAGTAATAA TATCAGGTTATAATACCATGTTCACAGGGAAAAAATACATACAGAACGTGTTCAGAATGT AGGTTTTTACCATTGCCTTTTAATATCAGAGACAATTCTTCTGAACACAGTCCATGACAG TGCTGTGAATGTGAACCCCTGCATTTCTGCCCAGCTCTCTTTTCAGTGTGATTGAGCCCA TTGAACCCAAGAGATTCTGGATTACCCACAGGAATAATGTTATAACCCATCACTGTTAAA ATGCATATATGTTTTTCATCCCATCTTTACAAAGTTTTCTGTTTACAGCCTTCAGTTATC CATTGCTACAAGGAGGGGAGAAAAGGCCTTCATAAATACCATAAATACAGAGTGATTGAT TGTCTTGATGTAAATTCCAATATAGGCACATACTGTATGCTCATGGAAATTTAGACTTAC GCACAGTTCATCTGCTCTGCCTCCGCCTTAATCTTTGACTGGTTAGCAGTCAAGATCATC CAGACACTGCTGGATGCTCATTTTTAAACAGAAACAATTGCTAAGATATATTTTTAACAA TATTCTTTCCCTTATTCTGCAAAAGCATAGGATTAACATTACATATTACAGATATTTTTT TCTAAACTACAACTCTTTTGGGGAAATGGGCATATGTCTCAGAGATAAAACACTATAAAA ATGATGAAATATTGATTTTATTTTTAAGACATACATTTAGGCCTCTTTTTAATTAGTATT GTTGACCCAATGGACTTAGCCTATGTGTTAACCCATATTCTTTATCATGAAAATCAATAA TATGGACAACTACTATGTTCCCACAGATGTTGAATGCAAAAAGACAAAGTTAGGGAGTTT ACAGAAGAGCTTGTTATCAGGATAACTTGACAATTTATTAGTGATGCAATGTCAGAGGCC ACCATCACTGCATTCTCTATGGTGTTGCTGGTTCACCAGATGGAAGTTATTTGGGCGTAC TAGTAAGTCTTTCCTGAAATATTACACCCTTGTTCTTTCTAATTAAATGAAAAATTAAAG TTGCTGATTTTGCAACAAGGATGCTAAACTACATACAGACATGATGTATGAATTCCATAT AGTTAAATCAGGCCTCGAAATTTCTGAAGTAACAATTTTAATAAAGACTGTCCAGGGTCT AGGCATGGAGGAGTTTGTGCTTCACTTGATAGAAACATCTAATAAAACATGGTTCAATCA ACTATGTTCAATACGTCCTTTCAAATACAGCAAATGAGATGAGATCATACTCTACTCTAC AGAAAACTATGCCTTCGTTTCATCTTTGGTTACTGAATTTAATTTAGCCAAGGTGACAGA AGGAGCTTCTTAACAGAGCCTTGCTAAACCTTTTAAATTATCCTTCCTAGCAAACTGGCC TGGCTATCACATTGCCCAAAGCATTCACCTTTTATTCAATCACACATTCACTTATATTTT CATTCATTAATTCACAAATCATTTATTTAACAAATATTGAAGTCCCAGTATGTGCCAGAC ATTGTGCTAAGTTTTGGCACTAGAAGATAAATGGGATTCCTGCCATCCAAGGGCCACGGT TCAAGAGGGGTCTCCAGTCTAACAGTACCTTCCTCTTGTCAAAATCTGAGACGATTGACT TCCAGTACCACTTTTCTAGCTTGCTTTTCTGATCATAGTTATCTCTGACTTATAACCATA GAATTTGATATCTGAGCAGGAACCTTAACAATGTTCTGGTTTAGCCACTCATTTAAGTCA TAAATCAGCTCTCCTTATTAATATGTAGTAGTAATGACAATGGACACTATTAATTATATG CTTGTCATGTACCAGGCACTATGCCAAGCCATTTATAGTCTTGCCAATTATAAACCCCAT TGGCAGTTATCCCCATTTAACAGATGATGAATGGACTGAGGCCCAGAGAGGCTTAAGTAA TCTGCACAAAGTTGTATAGATCCTTGCAACTTAAAAGTGTGATCCCTCAATGGGTATGAT CAGCATCACTTGGGAATTTGTTGGAAATGCAGAATCATAGACCCACCTGCAGACTTACTG ATCTGCATTTTAATAAGATCTCCAGGTGATTCATATGCACAGTGAAGTTTGAGAAGCAGA GGACTGGATAACAAATGAAGGTTTTAACTAGGATAAACTGACTCAAGCCCAAGAAGTTTT GTTGTTGCTTTTTATCACTTTGTGTTTATAAAATAATGGTGGCTGGGAAGTCAAGGGCAT ACATACACCTTGGAACATTTTATATAAGGGGCAGGAACTCAAATAGTATCTCACGCCATC AATTTTTATGTATTCTACGAATCCAAATCATATTAAAATAAGAAAAACCATGAAAACTTA AACAAGTAGCCTATTTGTTTTCTTTCATCCCTACAATTTAAAAGTGGTTAATATTTGATA GGTTAATAATAAATATTTTAATATAGTATATTGCATTTGGTTATGAATATATCAAAAGGA AATACAAAGTGAGCTCCAAAAGATAAACTTCTATTGGGCACATGAAAGAGAACATAAAAT TTGATGGCAATTACCATTTAATCTATTCATGTTTGGAAACATATTGAAAGAGAAACTCAT AACTCAGTTAATTGTTATGAATTATTAATTGCTTATTTGAAAAGAGATGAGCAGAACTGT ACTTGTTGAAAAACTTTCTTTCTCAGTGGCTAACCTTTGTGTCATTGGTTTTATGAGAAC AAAACGGAAAGAATGACAGCAAGATCCTAATCATCCAAAACTAGAAAGTGACAAGACAGG GGACATCTCGGTGACTATATAAAGGTTAATTGAGATTGAAATGAAATAGTAATCGCTGGC CCCACTCCAACCTTCTTAAGTGTGATTCTCTGGGGGTGGGCTCCAGGCATCTGTATTTTA CAAAACTCCCTAGGTGAGGATAACATGCAGCCAGGATTGAGGACTACATATTTAGCAATT ATACATTTTCGGAGAGATTTAATCCAGCCGTGAATTGACTCAGGATATTCAGAACCCCAA GTGAGATGCAAGCTGGCCTCCAGTTTGCCACTCCTAGTTAGACTTCAAGGTAACTAATGC CAAGAGCACTGCGGACTGTGGGAAGCTTTATAAAGACATGTTCCCTAGATGGTCAGTGAT TTCTGATCCCAACAGGCTAAGACCAAGAATATGTCTGGATTTAAAAATACCTGACTTAAA GAGTCCTTGCTTTTTTCCTCAAAAATCAATGTTATGAGCTTCTTCTGCTGGATTAAAAAA AAAAAAACCTTCAAAAAGTGGAAGCTTTTTCTATTAACTAAATCCAGGGATTTATTGTTT AGTGTCAGCAGCGTAACTGCTTTATAATTGATTTTTCTGAAAAGAACTGAAAACTTAAGC TACCTTAATTTCCTTTATCTTGACACACATGATTAGCATTGCACTGAAATATATTTTACC AGGTTCCCAATTACCATTTTTTAAAACCAACTTCCTCATTGCATACTTGTCTTGATAAAA TATTTCTAGACAGGTAGAAAGCAAGTAGGTATAAAGAAAAATGTATGACTGCTTTATTCC TACTGATAGGTTTATCCTGTTTCTTCAAGAATTCCTGTTTATGTTCAGTTATGTTTTTAA AAGTGAATAGAACTAGAAAAATATATTAACACCTGTTAATTTTTAAAGTCTTGGGATAAA GAAGCAAGAACATTTTGGACAACGACAGAATTTTAAAGATAATGAAACCAAATGTAATAT TTGCAACCTAAGCTAATGTGCCTAAATTCTTATAGAATTAGAAACAGCTAGCAGTATATG TCTGTTATTGTTGCACAGACAAATATTTAGTGTTGAAAAATGCAGCCTCAGCCTCAGTTT GTGCATGTAAAATGAAGATAAGAATTGGACCCACATCACTATCCATGAGAATTAAATAAC ACAATGAATTAAAATGTTTAACCCAGTTTCTGTCAGAGTATGGGCACGCAGTAAGATAAT AAAACTATAAATGATGGTACCCATCCTCAGAGTTTCATTGAAAATGGTGAGGAATGGATT AACAAATTTAAGAAATCAATTTACAAACAAATGACATAATAAAACGAAAGCTATGATAAT CATGGCTCCTTCCCGGAAAAAAAAAGAAGGCTACAAAATTATGGGATTTAATACCTATTA TGTCTTTTTCTGTGGTCGTTTCAAATACTAATTACCATCTGTAAACGTGAATTTTAAGTT AAGATTTTGTCCAAAATCAATGCCATTTAGTCTTACAGGTTCCAAATAGCAAAATAAAGC AACCTCTGATAAGTTGTATTCATTAAATTCATCCCAACCTTAGCAGCAATTCTTCATCAA TTTTAGGATCATCCTAAATCCTGGAAATTACCCTGTAATGCTAAAATACCTGCCTACTGG AAGGGTCTTGAATTATGGTGACCTCTAAACAGACCAAAAACTAAGTGGGGTTCTCTACCT GGGCAGAAACCAGTTATCCAGGAGTGATTACTGGGCAGTCACAATTCATAGAGTCACCAT CAGACCTACTGGATACTTAACTATTATCAGCTTGGTGACTGTTAATACCCTTAGGGGTTT GTATGTCTGAAACAAGCATTCAGTTCCTCAATTCTCAATTCCCTTTTTTCTTTCTTTCTT TCTTTTTTTTTTTTTTTTAGAACTCCTCAGGGGACTTTCCACGGGGTTATTTGGCTATTC TTAGCAAGTTCATGCTATGTGCTATTTTTCAGCAAAGTTAAGGTTTCTCTTTTTATGCTA GAAAGACTAACATTGAGACTCTAACTTTGAAGAGAATAAGGTTGTTTATTCCTGTAAAAA GATTTTTTAAAAATAGTATGATTAACAATTTCACCACATGTCACACTGCCCTTGAAAAAG TAAGGCTGAATTTTCCTAGTAAACTAAAAGGCACTGAGGAACAGAGGATGAGTTAATACT TCTGCAGCCCTAACACGGTTAACCAAAAATGTAAAAATGAGAAGGAAACATAACCTCCAC AGAGTAAAGAGACTGTAAGTGTGACTGTCATCGGCAGCACACTGCATGGACTCATTGTCA GGGGTCAGCCATCTTGGTTTCGTCTGCATTTGTAAAGTGCTGTCCTCCTACACACTATAT CAGTGTATTATTTTATGTTTTGACATGAATGTATTAGTCGTTGCAGCTAGATGTTGAGTG AAGAACCCCCAGGAGAGAGAGAAACAGTGTAAGAATACCACTCTGAAGGAGTATGGTAGG AAGAGAGACCTTGGTTTGAGAGGTTCATTAATCAGCAACCAAACATTTATTGACTGTTTG AATCCTGCAACATCATAGGTACCATATAAGATAGAAAACAAGTTTAACACAGCCCATGCC TTAAGGATGTTGCTAAACTTGAGATTGTAGTAAAACGTGAAATCGTAGAGTGAAACCAAA GTTTCCTGTCCAGAGTACTTAGAGAACTCCTAATGGCTCTGGTTGTGAAAGGAAACTGAA AACTCTAAGGTCTATTCCAGCTCAGTAGCTGTCTCTTATGTAGTGGTTTGAATCCTGGCT CTGCCACTTACTAAGTGTGTCTTGTTGAAAAAATTATATAACTTCTCTGACCTAAGATTT CACTTCTCTAAAAAAATATTATTACACCTCATTGGGGTTGTTATGGAATTAAATGAAATG CTTGTAAACTACTAAGCACAACATCTGCAGTAAAATAACCTCCATAAATTACAGCTATTA TTGGTATTACTGTACTATAATCAAGTGGTGGTAGATAACCTTGATGAAGTGCTGGGAAGG ATTTTCATCTGTCAATGAGCCACTAAACCTGTAAATGGAAATTCTGATCATAAATTTGGG TTTTTACAGAGTATTTGACAAAGCAGTAAATTATGTGTGTCTATCAAGGAAACATGGGAA GTCTTGGATGGTGGACAGTACACTTACTATGGATTCCTTAAAACTCTGAAATTCAGTGGC ACTATGGTATAAATAGAGCTTGAGTTTGTCCCCACAGAAACTTGTATTGAAATTTGATCC CCACTGTGGTAGTATTGGGAAGTGGGGCCTACAGGGAGGTGTTTGGGTCATGGGGGTAGA TCCCTCATGAATGGCTACTAGTGCATTCTAGTGGTAGTGAGTGAGTCCTCCTTCTGGTGA GACTGGATTAATTCTCATGGGAATGGATTAGTTCCCTTGATAATGGGTTGGTATAAAGGC AGGATGCCCCTTGGGTTTTCTTTCTTTCCAAGTGTCTGCTTCCCCTTTGACCTTCTCTGC CATGATACAATGAAGCAGGAATACCTTTTCCAGAAACCAGCATCATGCCCTTGAACTTCC CAGCCTGGAGAACCATAAGCTAAATAAAATTCTTTTCTTTATAAATCACCCAGTCTCAGG TATTCTGCTATAGCAACGCAAAATGGACTAAAACAAATGGGGAGTAGAAGTATAAAGAAT TGAAAGTCCATCCTTTACTGAGGAGGTACGTGACAATCCCTGGTCTCATTCCTTGGCCCT AAGGAGGTAACTAACTTCTAGAGAGTGCCTGAGGCCCCCAGCATTGCTCAGGATTCCCTC TGAGTATGCTGAGGCAGAGTATGGATCTTCCATTCACTGTGGCTTACTTTCCTGAATGTT CAGTGACACTGAGACTGTTCGGTGTCTCAACAGTGGTCAGCATTAATCCTTTGTTTTAGT GAAAGAAAGAATTTTCTCTTGTGTCTGACTTCAAATTAGAATTTTATTTTTTTTGTAAAG CAGCACAGTAAACTTCAAGTTTGTTAATAAATGTGGAGGCAAAGGAAGTCTTATACTTCT TTTTCATCAAGAAGGCAAAGCACCACCTATTCCTAGCTCCAACTTTAACACTAGTACAGA AAATAATGTTCCTCTAGGATATGGATTTTCATCTAAAACTTCATCCAGAAACTGACAGTC AAAAAGGACACTACAAACGCATTTCATTTTAAGAGAAGACAGTAGTTCACTGGGGATCTT TTCTTTCCCTCAGCAGGTATCTAGTTTCCAGCTACAAGAGTGTGCATTACTTACTGAAGA GTGTGTTTGAAAATATGAATAGAGATCATGACCAAAGCCTCCCAGGGGGTTTCTTCGGTC CAGCATAAGCCTGGATTTCTTCTACAATGTACTTAAGATTTTCCTGCTGACTACGTCTTT CTTTTCAAACTGCCATGACTTTAATAAAGAGGAAAGTGGATGCCATGTAGGGAAGTGGGC TAGACTCTTACACATAAAAACTCTCATGTTGTAACCACTTTATAAATTAAACTAAATTTA AAATTATTTCAGTAATAAACACACTTTGTGCCATCAGTATGCTTGGACATTTCACACATG TTACTTTATTTATTCTTCCAATAACCCTGCAAAGGAGTGCTAATATACTCATTTTAGAGA TGAGGAAACTGAGTCTCAGAGAACTTAATATGCTCAAAGCAAACAACTAGTAGCTGATAG AGCTATTATAAAATCAAAATACAGATTTGACTCCTTGCCCCACATGCCACACCAACTCAC TGTGATAGGTCCAAAATAAACCCACCTCAAGCCCAACCCTCCTTTAGAACCAGGAGGGTA ATAGGAACTTGCAGTGTTCTAATATTGGACCACAGCCCAGCTACAGGATCAGTTTGCTTT CAGTGAAATGAAAACAGCCCTCAGTACTCATTAATGGGAGTGTTGGTAAACACAAACAAT ACCACACAACAGAGAAAGAGACTTTAGGATAAAAGCAAGCAGTGACTGACAAGGCTTACC AATTCTCTCTCACTATCTGTTTATCATTTATCAGGAACAAATGTTTGTTCACTGCCCTCT GTGTGCAGTGAATTTATTTCTCAGAATCAACAACTATTGCACCCATGCATACTTTGCACA AGCAAGTTATACTCAGATTACCAGCTCACAAGGACAGTGTTTACTTGCATGCAGAGGAGA GACCCTGCCGTAAAGTAGACACTGCTGAGACATAGTCCCTACCCATTCTCATAGGCCTAA GATGTTAACGGAAACAACGGGCTTTCATTCCAAGGATGCAAATGATGCAATTCAAGCCAA ATATCCTGTGTCTTTTTACCAAAAAAAAAAAATCACTCTGACCAATTCCTCAAACCTGTC AAAAATTTAGATAAATAAACATCAAACTGTGGCCCAATAAGCAGACCCCATGTCACTTCA CTAATTAATACCCAAAGGAGGAAATAGCATGCATAAATAGCTATCATCTATTTAGTCACT GGATCATATATGAAAAAGAGGTAACCTTATTCCAACATCATCATCATGGCAGGCTCTTCG CATCATTTTATCTGATCTTTGCAATATCCCTATAATAGAAGATACCATTTTTTGCTTCTT ACAGATAAGGAAACCAAGCTTACAGAGGTGAAGCACATTTGAGGTCAGGAATTTAGAAGA GAAATGAATGAGGCTCAAACCCAGCTCTCTTCCTCTCCACCCCACACCAACATACATTCA TCGTTCAGGTGCTACGTGTGAGCACAGTGCTGTGCCAACTCTGTGGTAAGCCTTGTAGGG AAGCAGAGGCAAGAATGAGGAAGACTCTTGAACATTAGTCACTCACATGGTGACTATTTT TTTTTTTTTTTTCTGAGACTGAGATTTGCTTTTGTCGCCCAGGCTGGAGTGCAATGGGGC GATCTCAGCTCATTACAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTC CCAAGTAGCTGGGATTACAGGCATGTGCCACCATGCCCGGCTAATTTTTGTATTTTTAGT GGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTGTCGAACTCCTGACCTCCAGTGATCT TCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCAGCCCAT GGTGACTTTAAAAAGCAATAAAAAGTCATTATGCACAGTGTTGTCCAGTAGCCTAATGTG GTGCTCAGGATCAAGTGAACCTGAGGGTTGGATGCTGGAAGCAGGAAGGTGCCCATCTTT TCCAAAGCAGCAGGCTTGTTCTTCTTCAACAGCTGTGTTAGTGTGCGTAAAAAGTAATAA ATGCCTGACTCGCTCTGAGAGCCCAATATTCTCAGACAGGCAGGGCAACCACAAAGTGAC TCTACTCCACAGCTCTGTGGTGAGATGGAAGGTAACTGCTGTTGCACTGCAGCCATTTCT GTGAAATGAGGTGACAGCACTGGAGAGCATGACAAGAACAATACGCGGATGAGCCTTTTA CTGTGGTAGCAACTTTCATGCTGTCGTGTCAGTGCTACATGGTCAGGCTGCCTCTGTTGC CCCGGAGACAGGAATGGTAAGAATTCTCTTCATCATCAAATCATTAGCTGCCAGTAGCAG ACACCCTGTCTCAGCTCCATGTCCTGTGCCTGTCATTCCTTCTAAAATGGTGTATGAGGA AAAGTAGAGATAGCTCAATATAGTGATTGCACATCCTAAAAACAGGATCTTTGAAAACAT GGAGAGGTGCCACGAAATAATCCCTGAAGAGGTTTGAAAGGATGCACCCATTTCGAGAAG GGATAGAACGATTCCCCAGGTCATAACACAGTGTCCTATGATGATGGGAGGCAGGTCATT TCATCTTAGAAACAGAAAACCATTACATGCCAAGAGGGATGAGCAATGAAAGACAAAGGC CGTGAAGGAGCAGTGAAAAGCATCCTGGAATCACTTGGGGCTTTAAATTGCATGGATGGA TCTTTTTAAAGTGAGTAGTAAGATAATAAAGTGATGCATAGGAAGACTTGACACCCTTCA ACCCTGGTCTGATAAGCCAAAGGCTCACTTGGCTGTGAGCTAGCTGGGTTTAACAAAATG AAGGCCCTTAGATGCTAAGAAGATGTCTACATTCCTACTTTTAATCTTTTGAAGAGAGAG TGGGATTTGTACACAGCATGAGCAAGTTCTGTCTCATGCTATCTGATTTTGGAGTCTCTT GTAGGTCCATGCCTAATCCCAGAGACTGTAGTATTGGAGGATTACTCCCACTCAGATAAA TCAGCCATGCCTCTCTCAGAGCTCCCACCAGAATCAAGTAGAACCCTTGGTAGGCCTGCT CGCTTATCAATACTCCTAGCTGGATTTTAGAATAGCCTTTGATGTGGCTGCAGATACCAC ACTACATCTTATTTAATCCTTGACTCTGAAAGTAGGTTAAAGTATTGGGTAGCAAGTAGG GAAGTCAGAGCTAGTGTTTCCATTTGGTTTCATGTTTGTCCACAAAGACCTTTGTCTGGC TATGCAATGCAATATTGTTGCTTATGTAACGTGATGCAAGACCTCAGTCCCCAAGTTGGA TGACATTTGTGCTTAGAAGGACCATTATTACCAGATACTCTGTCATAAAATCTTTCTCCA TAAGGCCATACTGGAATGCCAGGTCTTAGGTCCATGGAATTATATATTTGGAGTGTTGTG TCATATAAATCAATATACTGATGAATTAATAATTCTTCTGCAGAAATGAAGCACAACACC ATCCACACATGTAAGAAATGGCTTCCTTTTTATTCTATCATGATTATAACCACTAGTACA ACTAGGTTATATTATCTGAAGAAAATACAAATCTCAAACCTCAGGCTTGCCTGGCCAATG CAACCTTTTCTGTGCTGCATTAGGTGTAAAAATATACAATTGTCCCAGTCTGTTCTCCTT CATTAAGAAATCACTCTTGGAGAGAAATAAAAGCCAGTAGACATCATCCAAATACAAAGT AAACACCATACACCTATCATTCAGCTTATTTTGTAGTATGAATTTCTGGCTCTTTTGGTA CTAAATCCCCAATCCAATACTTCAGCTTAAAAGAGCAGTACATATTTGGAAAAGTCTAGA GGCAATGCATTAGAATTCCATTTGCACCTTTTACATTTACCCATGTGCATGGCACTGTGC TCAGTGCTATAGATATACAGATATGAGCATTCATCCAACACAGTTATGTTGATTGTGTGA TTATGCTCAATTAATATGGAACTTGGGAATATTGTCTCATATCATGCTAAATTAAAACAT ATATGTGTCTATCCAATATTCATGTAATGCTCTAAGACAAATAGATTTTTTGGGGGTGGG ATTGTTTTCCTTTTATTAATGATCTAGAAAATCTTATGCATTTTTTAATAATAATTTATT TTTTAAGTTTTTTATAACAAGAAAATTGCCACATTCTTTTATAAATATTACAGTTTGAAT CATACATAAGCCACTGGAATAAATTATTTATGCCAGTAGACTTATGAGTTTGTAGTGTGG GGATGTGTTTGCCTCCTAATGTATTAGAAAATTATGAATCTAATACTTTGCCGTAACATC TAAGAAAAAGCACATAAATTTTGGGGGGCTTTTTGTGTTATGAGTACTGTAAGGAAATTT TTCTGAAGACATTTTTAATTTGTATATCCCAGCTTCCTTAGTTAGAGATATTAGAGAATG AGCCCGTCCTCAGCATGGTGTGTTTTTAGCCATCATGTTAGAGAAAAAGGCTGTTTCCCA TTAAAAGTTGCTCTCATTTGCTCTAATAGCCCAAGTGCAGATATATTCAATTCCAACATG TTCGCATCTAAAAGTTTGGAAGTGTAATTCACCATATGCCTAATGTCAAATATTAAAACA CACAGAACAATAAAAAGCTGATCCAAAATCCCCTTACTTTAAATCTATTAGTCAGATTAA TGGGGATGACACATGAGTTCCACTGTTATACTACTCCAGTGGCAATCTTCTAAAATTAGG AACTGCCAATCCGGGGGAAGCAAAAGAACTCTATATCATTTTAAATTTAACTCCAGCCTA CTCTGAAGCCATTAGAGGCGATTAAAGGAGATCTCTATCCATTAAATTTAGCCCAGTAAT CTTAAAGTTCAAAAGGTAAAAAGCACTTTTCACCATAAATAAACTGAGAGGCAAAATTAT TTTCAATGAAGTTTCAATTTCAGTGAAAATAAAGTAGGTAATTACATTGGCTATTACTAA GGTCACTGCCTTCATTGACCATCTGGCTTAAAATTAAAAAATAGGTATCATTTGAGACAT GGACAGAAATGAGCAAAGTGTGCACTGCTTCCTTTTTAAAGTCCTGCAAATTCAGTTAAT TCACAGATTAACAATATTCATGAAACAATTATTCAAAAATTAACCTGATGGCCTTTTTGA AGCTGAGCAACTCAGGAAAAGAAGAAGAAAAACATGTAATGTCTTACCATTAATTACCAT TACCATAATACCATAATTACTGCTTTCCATATGATAGTTCCTTGGCATATCATTTTTGCA TACAAAAATTGGTAGGCCAAATTTGTCATGCCAATTTCTGTAGATTTTCTGTATCTGGTG TCCTATTTGCTGGATGTGAACTTCATTTTCAAATTGGAAACATTGTTTTCTTGTAAGGAA TATAACTTAATGTTTGCCTTGTTTCGTTCTACTTCCTACAATCTCAGAAGGGATCAAAAC AGTTTAGAAAGTTGAACTTTCTAAATGCTGTTTTAAAGTCATTTTCCATATGTATTGTTT TTTATTTTATTTTATTTTTATCATTATCTTTTACCACTGAAAAATGGCATTACTGGATTT TGATATAGCTTAGGTTCACACTATCTATTATTACCTGAAGTATATCAAAGAGGAAAAAGT TAAATTAGTTCATTGCTTTTCCTCTTTTGTAACTTTGCAAAGACATATATGCATATTGTT CAAAAAGAGAGAGAGAGAAATTGCCTTTAATTTTATTTGAGTCCTAAACCTAGGATAACT TTATTCATATATCCTTTGTAAAACTCAGGTTCTGTTGTGTTTTGTTTTGCTTTCCTAACA TAAAGGCCACTAGCTTCAGGTTATGCTATTCATTCAGCCTGAAAATAGAATACATACTTT CAGAAGATCCTGTTCTCTGCATTCACAGCTGTTGGAGAGTCTTTGAAAATACCCTTGCCA GTATACAGAGATGTCAGCCTAAAGAACAGAAAGAGAAGATGGGGGAGGAAAAAAAGGCAG GGGTAAAAAATAAAAAGTTGCCAAAAGAAAAAAAAATGTATTTTCAATTCAATTTGAGCT TATTTCTATTCATTCAAGTCATTTGGAATTATTTGCAGTCAAGATTAATGATTCTTTACA GGTTGGGGGAGGACTTAGCAGCATCACCACTGATTTCTCCTGACAAAATTTATTATGCAT TGATGCTAGCAGGACACCAGCAGGAGAGAGTTTGTTAAAACACCTTCAGAATAGAGCACT TTAACCTAGAACGTTGCTCAAACGAGCTGTCCCAATACACGGTTTTGGAATGTTTTAACA CAAGCATTCATAGCAGCATTTTAAGATGGAGCCAGCCGGGTACTCCTAGGGCAAATTATT TGCTTGTGGATTTTCCAGTGGGGAAATTTAAATCACAATTCAGTATCCCTCAACTTTCCA ACTAGTCCCATGTACACTCAGGGAGAGCAAATGAACTTTTGAAGTATAAAAGTACAATTG TGGCTCTCTTTTTTTTCGCCTAATTTCTCACTTTGTTCTTTTCCTTTTCTTTAAAATATT AAGATAAGATTAGAAAATAATTTGCTTTGTCAGGAAAGGAAAACCTCTAGAAAACAGTTC TCAGTGCAACGAGCATGCAAGCTAAGGCCCGTTTCCTCAAGGGCAGAGTTTCAGAGTCAC AGATGGTTAGTCTGGGTTCTCGTCGTGAGCTTCATGAAACTCAGCTCATGCCCCGGTGCA ATGCCATCAAACCATGGCCTGCACAGTGCCGAACTGACAGTTCATCATGAGCGCACTCCC AGGTCTTTAGTAGCCTCATTTACCATGACATCGCTCCTCTGCTCTTACTGTCAGAAAGAG GTGAGCTCATTTCTCCTCAGCTTTCCTTCTGAGCCCTCACAGATAATATTTTACCAGGCA GGACAGATTTTACACTTTGGGAAAACTTTGGCAATTAAATCTCACAAAGAAATCCAATAG TTTTCTATTTAGGAAATGAAATTATTTCCTCTATGGCCCATGGTTTAATATTGACTTCTT ACGAATATTTATATTCACAGCAACTTGGCTGCACTGCTGGGGAAAAAGGCAGCTCTATGT GAAATAATAGCTGTAATTATTCGATAGCTTCTTTTTTTTGACAGCAGTACATCCTTCAGC TTTCACTTTTATACCAAACTGGAAATTAGGAGGTAGCCTAGCTGTGAAAACTGATGCTGG AAACTGTCCATCCATCATGAGGAATGATCCTTTCTCTGAGGGGAATTTGCTGCTGGATTG CCAAGTGCATAATATTCCCCTGGAGCAAGGCTGCATAAAACAACACTGCTGTGACACATT CTGAGATATTTAACTCTAGAGGGTCTGGCAGCCCCGTGTACTGGGCTGCTAATGGTGTTC AGTAGTTGTCATCGGGTCTTAGAGCCCAGAAGGTCAGAAGAATTTCTCTAATCCTAGGGT AAGAGACCAATTAAAATCCATCCCAGCCAGGACAGTCTCCACAAAATCCATTATCCCTGG CCTATTTTTAGGCCCTTAAAGGATGGATGCTGGGTGAAACAAGACAGAGAAGGCTTTAAT TTATTCAATACATGTGTAAAAAGCGTGAATTCTATACCAGCCACTGCTCTGGATATTGAG TATACTGTGTTAAGAAGACATACATAGACCCTGCTCTCAAGGAGCTCATACACTGGTGGG AGGCACATGGAAAACAGGGAAAGAAATAAACAGTGGGCAAAGACCACTGTAGACTGAATA GTCATTGAAGGTCTTTCTGAGAAGGGAGTACTTCAGCTGAGATCCAAGTATTAAGGAGAC CCCACCATGGAAAGTTCTGGAGGAAGAGTGTTCCAGGCGGAGGAGACAATTCCTGCAAAA GCTGAAAGGCAGGAAGGAGCTGGGCCAGTTCAGAAAATGGAAGGAAGCAAGTATGGCTGG AGGGTGCTGATGAGGGAGAGGTGGTCTGAGATGCGAAGAGGAAGATAAACACCAGATCAC CCATCCTTGAAGGCCAACACTAGAGATATGGATTCTCTTTTTTTCTTTTTTTTTTCTTTT TTTTTTCTTTTGAGACGGAGTCTTGCTCTGTCTCCAGGCTGGAGTGGCACAGTCTCGGCT CACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCCCCTGCCTCAGCCTCCTGAGTAGCT GGAACTACAGGTGTGCACCACCATGCCCAGCTAATTTATTGTATTTTAGTAAAGACAGGG TTTCACCATGTTGGCCAGGATGTTCTTGATCTCTTGACCTCGTGAACTGCCCACCTCAGC CTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCTGGCCTAGAGACATGGATTC TATTCCAAGTTCCCTGGGCCTTGAGCAGAGGCGTGCCATGATATAGGAGTTTAAATTAAA AAATAACTCTGGCTACTGTGTGGACAATGGATTGCAAGCAGGGGCAAGAAGGAAAGGGCA AGGTTTGTAATTAGCAGGATTACAGTAGACCAGGTAAGGGGTGTTAGTGGCTTGGACCAT TAGGAGCAACGCAGATAATGAAAATAGATGGATTTGGGATCTGTCGTAGTCTCTGCCTGC CTTTGCTGAAAAAGTGTTAAATCTAAATTTTCAGGTGGTCTGAAGCAAGGATGCACTTTT TCTGTTTTCTATTGCCCTTGCCACATGGATGCCTTGTAATAATGGTTCCTACCAGTTTCT GTTTCGTGGAGAAAGAAACAAGGGCAAAAGTAATAGCATTCACAGCATTCCAGCATATAG ACCTCGAACAGAACATAATGATCAGGAAAAATAGCAAAGTAATTAAGCTCACAGAATTGG GTGGGTTACAGGCTCTGCTACCCACTACCTGTGTGACCTTAGAGAGACTATTTACCCTCC TCAAGTCTTGGTTTCTTCACCTGTCAAACTCTTAAAAGGTCTTTCCTTGTAAGATTGTTA AAAGGATTAACCAGTGCATGAAAAGCACTTGGAAAAATGCCTGATAGGAGACCAAGTCCT CAATAAATAGATGTTCGCTTTTGTTACTATTATTATCCTGTTTTAATTTAAACCTCACCT TCCACCACCAAATGTGATACATTTAATGGCGTATCAACATGTGCTTTTCCTTTAATTTCC CAAACAGGAAGCCAAACTATGTAGAGGCTTTTTGTTGTTGTTTTTAAATATCTCTTCTAA GGAGAAAAGGAACTAACATTTAAGAAGTTCTTACTGTTTGCCAGATGTTTCATATATATC TCATTTAGACCTCTCTATAATCAACAGAGTTACCATTTGTTGGTAAGATTTTTATTTGTT GGTACCTATTCTCATCTTCAAAACTGCCTTACAGTGAAAACATGCTGTGCCTGTTTTATA GATGCAGAAGCCAAGGCTCAGGGAGGTCACTTGATTTGCCAACGCCCCACAGCTAATGAG TTGAGGATACAAGATGGGACTCTAGATCTGTGTGACTCCACAATCCTTGCAATTTCTCCC ATACAGTGGGGAAGAGACAAACTATACCAGCCTACCTCCAATGGACTCTTGGCTGCACTA TCAAACAAACCAGGAAAGTAGGTTTCTCCCCTCCCTTTCCTCATGTCAGCTGAGATTTTC ATTGTGCCTTGACTAACTTCCAGTTAGGAATGTTCTGTGCTAGATTCCTAGTCTAGTTAG TATGTATTGATCATGTATTTGGATGTCATTAGGCAAGTACTCATCATCAACATGAATTCG TTATGTGCTTCTTAGGAAATTAACTGATAAAGGTTGGAAATCACTGAAAATCCTTTCCTT TTTCAAGTGGTCATCCAATCTTTCCCATTATTCTCACTTTATTGCTCTTGGCAATATAGT TAAGAATCTATTGACGTTAACATTGTAAACTCAATCTGTATCATGTCGTTTATAACTTGG TCATAAAAATCCATTTATCCTGAGATTTTGGTGTAATTCTTTACTGGCTGAATTGTCAAA ATTTTCATCTTATTAGTTATGTAATGCTAGAAAAAAATAAGACACAATTTCATTCCATAA TAACCTTGGTTTTTTTTTTTCACTTGTTCCCAGAAAAATAAAGCAATAAATTTAAAATAG AAAATGAATAATCTATAATATTAACTAAAGCATTTTTAGCTATTTAAGCATTACATCAAA AGAAAATGTAAGAGTTTTTGTCAGCAAATTATTGAGAACCAAAATGTACTTGTGGCTTGC AAGATTTTTTTTCAGTTTACTCACCAGTCTATATAAGGCAAGAGCCCTGATTATGTCCTT AGGAGTCATTTCCATATGTTTACTAAATTATAGTCCTTATTTCTTCTTCATATCAACAGT GACCCTAAAAATCAGCATGTGTGACCCTAAAAATACAGAAAAATGCAATGTATTCACTTT TAGATACATTTTCATTTGGTGGATTTGGGGGGTTTGAGGTTATTTTGAAAATATATAATT TATTTCCTAGACTATATAAAAAGGAGGCATCTAATAATCATTTACTAAAAATTAAAAGCA ATTAGTGGCAGTTAGGATGAAGGCTTCAGTATTCAAGTCTGATGTAATGACCTTGCCCTT AATTCAATATCCTTTGAGTTGTGTGTTTCTTCCCCTTTAGTTAACATAAATAGGGGCATC AGCTTTACACCCTTAAAAAAACCTTGTTGCCCATCTTGTGAATCTTTTCTTTCTTCGCAA TCTGTGAATAAACTGCTTTGCTTTGTCTTGTTAAAGCCAGGCCAGCCATAGCCTTGGCCT TTAGACTACAGTATTTAAACTTTATAGGTAGATTTGACAAGCCTAAAGATGGATAATCAG TCACATCGTTAGCACAAAAGAATTGCCCGATTAAGCAGGACAGAGACCAGCCTGAAACAG ATCCTGATAGGCTGAAGGGATGTTCAAAAGATTTGCCTAGTTGGGGCCCCAGGTGTAAAA AGCAAGCCCAGCATGGAAATGAGTAACTCAGACATATATGAAGGGGCTAGCGCAGCAGTG ACAGGTGGCAGGAACCTACGGAACGAAGGGTGAATGGGAGCAAAGACCTTTAGATTAACC AAGAGGCTTGCACGGAACAACAAGTGAAAAACAATTAGAACCCTGGAAGATAAAACCAAA TGAAGTGATCCAAGTGAGGTCAGACAGCATACCAAGCAGCAGCACATCCAGTGACAAGAA AAGTGTTTGTCCATGCAGGTCTTAGCTTCAGCCTCAGGCCAAGTTCGAATGGTAATGGGA GTGCAATAGGTGGAGAATCTGCCTTCCACCCTCCTGCACCTTTTTATGGGAAGTCCGTGA GATTCATTCATCACTCTGATACAAGAAGCTAAATCCAAGATACAGTTTTAGTTTAATACT TTGAAGGTTTTAAAGTTTAAATGTGATTCCTACCCCTAAACAAGCAGAGCTGAGATGCCC ACAGGGAAGGATGGGCCCCACGTCTCTCCATAGGCTTATGTGGTGTTTCTCTCCAGGTCG GCCCAACCCCACATTCCCCCTCCTTCTCTGTCCTCTTTATCTCCCTCTACTGCCCTTCTC ACCACAATACAAGAAACAGAAGCACAAAGTTTTAAAAACTGCTAACAAAGGGACTTTTTT GAAACCAGTACTTGGAGGCGTTAATGAAAACCCAGGTTATTTCCAATTACAGTCTCAGGA ATTACTGAATCCTTCCATGACCTTAGAAATGCAGAAGCCACGTGAAAAATCATCATTGGA AAAGAAATCATTGAGAATCCCGTTAGGTGCCAGAAAAAAAATGGATGCTTAGGATTCAAA GATAAAATAGATATCTGAGGCTATAAAGATGAAAAAGGTGTCTACTACCTTTAAGGAATA GTGCTTATAGACGGACTGCTCTGTCATGCACCATACTGTTCTGTGTGGACAATGAGAGGA GGTGCAAGACAATGGCCTGCCCTCAGAGTGCTTGTATTTTGGTTGAGGAGACAAGAAATG CACATGGAAAAGGAGTGTTTGTTGTAGATTTTGCAGAGTCATATAAAGCTTACATTTCTA TCTATGTCTATATCTTTATCTAGATCATCTGCCATAAGGCTTCAAAGGAAGGATAGTATC TGAAGGCTTAAACACTCACAGAAATAAATTTCCATGGTGGGGGTTGTCCATGAGCAAGAT CTTAAAGAATGGGTGGAGAGTTTAGGGAAGGACATATCTGGAGCAGAGACACCTCTACAG GGGCAGGCATGTGGCAGTCCAGGGACCAGGGAGAACATGGACAGTGCTTTGCAAACAGAA AGACTTCAGCTCTGATCCTGCCTCTGCTGCTCAGTCGCCAGGAGGACTTATGTAAGATCC ACAGGTCTCCCATACAATTGAAGTAATAATAATAACAATAATACCTATGTACCAGATTAT TAGATATATTCAATTAGATAACAGATGTAAATGTTTCTGGCCTTTTAATTATAACGTGTT AATTTTAATTGTGTGTGTGTGCATATGTGTGTGGGAAGGTGGTATGTAAGTTTAAGACAG TAAGTATATGATCCAGGAGTAGACATTTCATGTTGTGGAGTAAAAGCACATGATGGGGAG ATTCTGAACACACTGTTGGGAGGTCCTGACTATAGTATTTGCAGTTAGCAGTGGGGAGAT TCTGAACACACTGTTGGGAGGTCCTGACTACAGTATTTGCAGTTAGCAGTGGGGAGCCAT GGAAGATTGTGAGGGAGAGAATGAGTGAGAAGTATTGTGTAAACTCTTTGTGAGGAAGCC CCATCTGGCTGTAGCATGTCTGTGCAATTTAATTTAGGGGATATAAAATAGACACAGTTG AGAAGCTATTTCAGAAGTAAAGAGGAAGCAATGGATATGGAATATGTCATTTTTTCTATG AAATTCATTTATTCATTCACTCAAAATACTCATATTCATTGAGTACAGTTTGTTCTCAAG CACTGTTCTAGGCATTGCACACTCAGCAAAGAAGAAAGCAGTCAAAATTCTTATCTTCAT GGAGCTTTTATTCTAGAATAACTCCCTATTCATATAAAAGTACATATCTTCAGAAAATAG AGTAAGAAATGTCGAGGAAAGTGAAATGTGTTAGGACAAGATATTTTAAAGCACGTCATG TGATTAGTCTTTAACAAGTCCACCCAAGTCTTTTTCATCACTGCTTAATCTAACCTGGGT ATGTCTTAGTCTGCTTCAAAGAGAAGCTCTAACATCTTTTCCCTGTGTTTTAAATACCAT GCATAGCCTCCCAGTTGTATCCAAACCAATTCATAAATTTTTTCTCTCTGCTGCTGGATC TGAAAGTCCCTGAAGGCATAGCTTCCACACATTTTTTGCCAGACTCTGATTTTGGTTTAA GTATCTTACCTCTCTCCTGAGACACAACAGCCTTGCTCTTCTTCGAAAAGCTGTAAAATA CCCTTCTGCATGCCCGTAATGACTTAATTTCCCCCCTTTTCAGGTCCACTAAGCAGATCT GTTCTCACTCAAATACCTTTTTCTTAACCAATGAAGAAAGGATTCCTCTGGATATTAGGA AAGAACTCAGTACATCCTCTTTCTGCCTCATGTTTGAAGTTTGGCTTTAGTAAAAGTTAT GTTGCACAGAATTACTTAATGTTACTCATGAGCTTGTCTAAAGTCACTGTCTTTACCTAA ACTTTTTTTTTTAATAAGAGCTCTTGTTTATTTTTCTCATCATTAAAGAAAAATTAACAA ATAGATCTTTTCAAGAGGTAAGCAGCTATTGATTCATCCAAGAAATTGTAGGAGTGAACG ATGATTTTTTTCAAATTGACAAGTATTCATTAAGCTAGAAATTGCTAATGATAAAAGTGA ACTAGAAGACACAGGAGTATGCACTATGTGAAACTTCATTACCTAATGAAACATAAAAAG CATGAACCTATATTAACAATTACCATTTCTGTGACTCTGACAGTCTATCTTTTATTGTAG GACTTTGAGCAGTGCCTGGCACTTACAAAGCACTTAATAACAATCATTGAGTTGAATGAC CTCTCATGTTCACAACAGCCCTGTGAAGTGGCCTCTTTTACAGATGAAGAAATAGAGGCT CAGAAATCCAGATTGCAGAGCCATGCGTGGTAATGTCAGTATTGAAATCCAGACTTCTGG ACACCACCACAGTAAATGATCAAGTACTAAACTTTGTGGTTCAAATTTTGAGTGTCTCAG GAATTTGTAAGTGGGAAAGACAATGTGAGTTACAATAGTCAGCATCAACTTCATTGAAAA GGTATGCTATGACTTGTCTATAATCTTAACCTCTTTGTCCTTTCTTAGCCTTGCTGATGT ATTTTAAGAAATTTAAATGTTTGGTCTCCAGTGCAGTAGCAAATATACTTTTGAAAATTA GCAGTCATTTTTACTTGGAATCAGGCATCCCTAAATGGCTCCTGTCATCATTTTGCACAT TCTCGTGATTCCATAATGTTGTTTTCCTCACCTTGAATTTATTGACACCAATTCATTTTG CCTTGACATTGGCATTAACAGGGAAATGGCTTTGTTTCATCCTGACATTATAAAATCACC TCCCAAGACTTGGTTTGACATTGTCAGGGGGTGGTTATGGTGACAGCAAGGCCACAGCAG ACAAGAGTGAATTACAGCGATTCCCTGGAAAAAAAAATCATTAAGAAAAGTTACCGCTGT GTGATTTTAGTAGCTATTTTTCATACTTAAATATCCCTGCTGTTTAAAAATCCTAAGAGG GCTTAGACCATATTTAGAACACTCCTACCAAGTATGTATAGGAAAAATTAAGTCTCTAAG GAGACGTTTGGCTATAGCTTGACAAACAGGAACCTCAAATTATATTTTAGCTTTACAAAG TGCTCAAAGGCATTGAAATTCTGCCTTTTAAAAAAACGCGTATTTGAATTGATGACACAA TTATCTCCTTTCGGCTGCAGATACTTGCATTTCTTAATGCTGGGATATCAAAGGCCTGTA GTATTTTCCTACCTCCTAGCCAGAATGTAGAATGTTTTACAAATTTGTCTTCAGCACTGT ATGGGGTTGGAAAGATTGTCTTTCATAATTCCAACATCATTTCAAAGAACACCAAATCCT TTTACTTGAGTTCTTCTATGTTCCCATAATGGTTTCTCACCTCGGCTGTACTCCCACAAA GAACAGCTCCATGTGGATTTTCCTTTACCCTATGTTCCAAAGTTAACTAATCACCTTCTC AATTAAATAAAAAAAGTCACTGAGATCCTTCAGGTCTTCAGGGCCATGTTGTTTTCACCT TTGTGTTGCTAGCAATGCCCAGATTATAATAAGAGCTAATACATTTTGCTTAATGAAAAA TGATAGGAAGGCCGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAG GTGGGCGGATCATGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCTGT CTCTACTAAAACTACAAAAATTAGCTAGGAGTGGTGGCGCGCGCCTATAATCCCAGCTAC TCAGGAGGCTGAAGCAGGAGAATCGCTTGAATCCCGGGAGGCGGAGGTTGCAGTGAGCCA TTATCATGCCACTGCACTCCAGCCTGGGTGACAGGATCAAAACTCCATTTCAAAAAAAAA AAAAAAAAACAACGAAAGGAGCGTTCCTGATCTTTTATTTCAAAGCAATCATCCTTGCTG CTTCTCCTCTCTTCCATCTTTTCCCCAAGTGTATATTGTTTCATGAAGAATGACTTAATA CAAGTCACCATTCTCTTCCTGTTCATGCTTCCATTATCAAACCATGTGTATGGGAATCTT TGACAATCATGGTATCCAACCTGAGTTGGCAAGTCAAAGCTGCTCAGCAAGTTTTCCATG TGTTAGTTAGCTCCCTCTCCCATTCCCTGCCAAATAATTTTCCCTTTCAGCTAGCTAGCT ACTAATAATAGACAGACATCCACCATTCGGAAACAGGCATACAACAAAATTTTATTTATT TTATTTTATCTTATTTTATTGTATTGTATTTTTTGAGTCAGAGTCTCTCTCTGTCTCCCA GGCTGGAGTGCAGTGGCACAATGTCAACTCAATGCAACCTCCGTCTCCCAGGTTCAAGCA ATTCTCCTGCTTCAACCTCCCCACCATGCCCAGCTAATTTTTTGGTATTTTTAATAGAGC CTGGGTTCGACCATGTTGGCTGGTCTTGAACTCCTGAGCTCAAGTGACCCTCCTGCCTCG GCCTCTCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTAGCTTATTTGTTTATTA TTTATTTAGCATCTATTCCATGCCAGGGACAGTGCTGAATACTAATGACAGCAACAATAA ACAGGTAAAAGATGTAGTGCAGGTACGTACAAGGGCAGAAATAGTTTTTTTTTTTAATTA GTTTAAATTCAACTTTGATCCCCTCTACTAGAAAGGTGGTGAGATATTCAGCCAACTGTC ACTGTGGCTCAATCTACAAATGTAAAAATGTCCACTCATTTAGCACCAGTCTCTACTAAT TACCAACAAGATGGTCATCCGTTGGGTTGCAGATCCCTTTAGCTCAGGAAGCTCTGATGG TTCCATTCACATCTGAGGCTGTGGAGTCATTGGCAAGCCAAGGAATCAAGTCTAAGACCC CTTCATGGTTATGGGATTGTGTAGAAACTCATGCCTTTTCTGAGATAATTGGTAGTCCTA CTAGAAATATGTATTAGTAACACAAATACTGAAATTTGATAAAATGTGATTACATAATTC ATTTCTTAACTGAATTACCTTTATTATCTAAGTAAAAGACACATATTTCTAAAAAAAACC CAGCAATTTATTTTATTAACATTTTTAATATCACCAAAGGACTATATTCTAGGCAATTTG GAAAGAGTGAAAAGTATAAAGATGAAAATTAAAATTACTAAAGTTTATTGCACTCCTACC AGCTATAAATAAACACTGTTCACATTTTGGTACAATTGATTGTAGTATTTTTGCTAAGGT TTATATTACACAGGTATGTGTAGAGTTACATGTCTGTACTTATGGAGATTATGCTGGATA AACATTTTGTATCTGCCTTTCATCCTGGCACAATGCCATGTACTTTGAAACGATGATTTT TACCCTGATATGTGTTGCCATTTTGTGTGAATATGCCTCCCCATGAATTCCATCTTTCAC CTTCAGCTAAGAGTAGAGGTTGCAACTCTTATTAAACTAGACAAGTGCATTTTCTGATAC CTGATGAGAAAGTCTGTGACTTCTCAGCACCATTTTTATGAGAACCTTGTCTGTGTCTGT GTCTGAAGGTGTTGACCTAAATAGGATTTCAATACATCATTAATGATCACTTTGGGAGAG GTGCCCAGCCTTCAGCTTGTAGGATTCTCAGTAAATTAATTCTTTCTCGATATCAGCAAA GGCTTTTTTTCAGGTTGCAAAGGCCAAAAATTTTAGGGATGTTTGGGCAGGGCCTCCTGC TCCTGCATCAGAGTCACCTGTCACCTCTTTCATGCTAGCCAGGATACTGTGAACTGCAGA ATGGTCTCCTTCTAAATGAGTGAGGCTCTTTAATGGTGTTTTAAGCAGTTTTTTCTATGG TTTGGCAAAAGAAAGTGTCACTCTCATAACAGGTGCTTTAATATTAGATGAGTAAGAATA GAATGGCTACTCCCTAGGGTCAGAACTTGCAGTCCTTGATTACCTACATGTGTCCAACCA CCCAGCCAACAGCTTCCACATTGTTCCCTATAGCAACTTCAGCTCTGACCCTTGGGTTCA TTATGCTGAAACCAAGTAGGTCGGATGCTGTCACACAGAGTCTCGCCACCGAAGTACCAC TGTCTTCAGATGCATACAGACAAACTTGAGTGTAAATTAAAAGCAGGAAAGCAAGGGCAT TTTCACATGAGTCTACCAGGTTTCAGTCTGTTGTTTGCATCCGTACCTCCCCTGGCCCCC TACACCATCAACATTGCAAAAGACAAAAGGTGGGCTATGGAGCAGTAGATGCAGGTTGAG GGTCTCCAGCTCAGCCCCTCCCTGCTACTCTGGAAACACAGCTTATTTATGTGCTCTGAT TGATACAGGAGAGTGCACATTGAATGAGAATATAGAAGTCGTCTTTGAGAAAATGGGCAC TGCCACCCTAAGGTGACCTTGCAAGGCTTTGTAGAATATGCAGTAGTTGAATACAAATAT TTGAGAATTGCATGTTTTGACCCCATGCTTGCTCAAGTTTCATACTAGCAGAAGACATGC ACAGATGCTGTCTTTGAGGAAGGACATTTGCTTCCTTTTATACTTCAAGTAGCTTGGATT GGATAAGTAGTGTTTAATTCATTATTCTGGCAGAGATAGGAATTAGCACCTCATTCTTCC ATCCTGAGCTTCTAGCACTGGGTGGATTGAGGAAGAAATTGAACTTTAACAAAGTATACT TAGGTTGTGTTTTATATTTTTTTAGAGCACCTCCACATAATTCATCTTGAGGCTACCAAC AACTATTAGGTGGGTAAATAGGACAAGTGTTATTATCCTGCTTGTGAAGTGAAGAAAGGC ACAAAGAGGTTAAGTGATTTCCCCAAGTTCACTCAGCCCATTAACTACAGGGATGAGACT TGAATCACAGAATCTGAGCCTAATTCTCTTTATACTACCTCATGCTTTTAGTGCGTATGA GGGAAAAAACTATCCCTGTTCCATGGGGCAGCAGATAAGACTGAACCAAAACAGATCAAA CAGAAACAGTCACCTAAGTCATCACCAAGGACTCTATTACACAAGACCATCCATCATCAT ATATTTGGTCAAGAAGGGGAGGGATTTCTAACACTTTGCCTTCAAAATGATAGGCTTTCC ATTAAAAATATTCATGCAAATCATAAAACTTGAGAAAACTTTAGAAATACCGACTTCAAA CCTGTAACCTGTAGCCTAACTTTACAGCTGCAACTAGAATACAAGCCCCTCATGTGCAGC TCCACTGTGGGTCTGGCTTACCAAAATATGGCCACCATCCAGAGCAGTGCCTGGGTGGAT GTTGGACAAACGCATGGATGAGTGTCACTAAATAGTTGCATAGTATGTCCAAGGCCTTGT CGTAAATGGATGACTAGTGAGACCCAGATCTCAGGTTTTCCAGTTTTATGACGCTCAGCC AATGTGTTTTCCCTTTGCACCATACTACCCCTCATGGCCAGACCAGACCAGACCATAAGG TCGGGGAAGAAAAAAGGTTTTTTTTTGTTTTGTTTTGTTTTTTTGTGGGGCGGGGATGGA TTGCAGTTAGTGTACCTAGAATTCCAACCACAACAACAAAAAGTGATTAGATAACAATCT ATAAAGTTTCTTCCATGGCCCAGGAGCTAACCTGTAGGTTCAGTTTTCCATCTCACATAT CACAACTTAGCAAAACAGCTGCAAAAGCTGTATAAATGGGTCATAATCACAGCTCTTCAA CTCCCTGCCACACAGTCTCGAATGCCTAAATCAGACCTGAATGTAGCCCACATACCTTTG TTATTAGCCTGTTTGGTGGAGGTTATTCACTCTTTGATGTTTCTTTGAAAAGGACGGGAA CAATTTGGAACATCTTTCTCTCAGCAATCCTGGGCTTGTTTCAGGTGGTAAAGGTAGAGG TCACTTTATTAATACAACCATCAAGAAAAGCTGTCATGGTAACGCATTACATTGATTCCT TGAAGTGCAGGAGACAAAGCCAAAAAGAGAAACTTTCAAGTCTATAAATACAGACCCAGC ATTGCTCAAGCATAGCAGCTCACTGACAGCATGAACCTAAATGTATAACGTTGAACAAAA CCCAGAGAAAAGAAAACTTCCCTTTGGTAGTGGAATGGATCATCATGACCTTAGGGGAAC AAGTGACCCCTCAGCTCATAAAAGATAAAAGAATAGAACAAGTGGCAACACCAAGTCCTG GCTAATACCCTCTGAGCATAAGGAGTCCATCTGTGGTCAGTTTTTCCATACCTTCCAGAA AGAACTCATAGAGGGGAAAGGAATCAAGGTCTCGTAAGTCACATTTGACAGTAGATTGCA GTTTGAGAAGAGGAAATGTATGTGACAATCAAGAAACCCACCAAAAAAATGAAAGAATTA AATAATTTAGCTATATCCCTGTGTCGCTCCTCATCCAAGATGGTGCAAGAAAAATAGATA GAAGTAAGAGAGGAAGAAATGCTGCTTGATCAGTTCTTTCACTGTGGAAATTCTAAATGT TTTTGTAAACTCATGGCAATTGTGAGAGCTTGTTTATCTACCTTGTGGCTTGCTTGCTAA AGCTATGATCAGAGCTGTTACAACACCTTGCTGACTTCAGCTTTTCCACCAGGTTTCCAC ACTTCATCTTTTGGCCACGTAACTCTGTTTGAATCTAACATTAATACTCTAACCTTATCT GTCAAATTCCACAAATTATCTTGGTCACTCCATTTGAAATCATTCCTAATATCAAAACAT CAGAGGATTATAGTATGTGATATTGGATACTCCATAAATGAATTATATTTATCAATACGA AAAGGAATCCTTTAGAATACAGTCAAGCTATTACCAAAGCAGTATTAGTTTTTCTGGTAT CTAAGGATCATATTTTACTATCACAAAAAGAAATCTGTCTAGCAAATAACTATTTGCATC CAGCACTGGATCAAGTGTTGTATAAGGATTTTAAAATGAACCTTTCTGTTTACTGACATA GGACACTCTAAGACTGTCAATAACAATAAAGAGAGAGTTGGGACATGCTTAAAATGAATA CACCCACAGAATAAGTTTAGAGTTTTCAGTCTGAGGTAAACCCACAGAGCAGGGCACCAA GTAAAAAGTGTGATCACTGAAAGATGCCTGTTGGGTAGAAATTTTCACTTGGATCTTTAA TTTGCAACTATATGCAGGATTATGTGAGATAATGCCAGGATTGTAAATGGGTGTTTATCC TCATGCCAGTACTATCAACTCATGGTGGATGCCTGGAAACTTGTGTTGAGAAGCATTTGA AGTTCAGTGCAAGAGAGTCCCATGATTAACTAGCTGTATTTCTGACTTATTCCATTTTAT GCACTATAACAGAATACCACACACTGGGTAATTTATAATGAATAGAAGTTTATCAACTCA CAATTCTGGAGGCTGACAAGCCCAAGATCAAGGGGCTCACATCTTGTAATGGCCTTCTTG TTGCACCATAACATGGCAGAAGGCATCACATGATTGAAGGGCAGAGAGAGAAAGAGGAAA AGAAAGGGTCAGCCCACCCCATGATAACAAACCCTCTCCCAAAATAACAGCATTAGTCCA TTCATGAAGGTGGAGCCCTTATGAGCTAAACACTTCTTAAAGGTCCCACTTCTTAATACT GTTACAGTGGCAAATAAATTTCAACATGAGTTTTAGAGAGAACACACGTTCTGTACATAG CAGTCTCCTATGTACAGGGGAAGAGGAAATGACAGTGTAAATGCAGACATATTTGCCATT TTCAGCCTAGACATTGGCATTTCTGGTTTATTTTCTGTATGAGCTGATTTGTACTTGGAG CTCTACCAAAATGTGGTAAAACCCTAGGATGAGTAACAATTGATACTATCAACAAAGACC TCTGCCTAGTCAAAGTGTGATATGAAAGCAGAGCACTTAGTCAATACAGCTGCAAATCTA CTGACTATCTATAGAAGAGTTCATGTCTCCCTGGTAAGTGGGAAAGTCAGCTATGTTTTG AGGAGCATGGAATGTGGCACTGTGCAATATTATTTACCACATTTCTCCTGATTGTTCTTT TCTATGTGAAGAGCAGTAATCTATAAATTGGGAGACCTGGATTCTAGTCCCAGTTCTACT CTCAATTGCTTATCTACAGCTTCCTTATCTACAGCTCATCTAGATGGTTTCTAAAGTTTC CTGCAAGCTCTGATTTTACTGCTTCTATGCAAGCAAATTACATAGCAGGGGTGCTTTTTG TTCCTCTCACCCTTTCATTGTGAACAGTACTAAAGGGTCTGTCTTAGATCCCAGTCTCCT ATATTTACTCCCTGAAGAAGATAATCCACTCTTACATTTCCAATTCAAGTACTTAGTCAC CTCTAATTCCCACAGCTCAGCACCTGAAAACTTACTATCTTCCTGATCTAGAAATGACAA AGTTTCTTTATTGTACCTTCCCCAAAATATATCAGGGACAACTGCCCTTCTTCATTGCTA TGACTGATGCCCTGACCCAGGCCTTATCGTTTTATCTTTTACATTAATTGAGAAGTAATT CTTTGTTGTGGGGGGTTGTTCTGTATACTGCAGGATGTTAGCAACATTCCTGGCCTCGCT ATACACATCAGTGGCCAGTAGTGTGCCCTCCCTACCCACTTGTGACAACCAAAAAAAATG TCTCCAGACATTGTCAAATACCCATGGGAGCAAAATCATCCAGCGTTGAGAACCACTACT TTAGACTGACATCCAAAGACATCCATTAAATGTTAATTCTTCAAAATTTTTCAATCCTTT TTCCAATTATTCAAGAACCCCTTATGACAGAGTCAATCAAGAACATGCAATGTTTATTTT GCATATTTCATTTGTCCAACTCAAAGTGCCCTTACTGTCACACTTTTCCAGTTTGTCGAT TCATAGATACAGTCATTCACATCAGGAAGACTTCTGCGGTTAATTTCATACCTTCATAGG ATCACTGCATTTTTCTGACATTGTTTTCTTCTCAGCATCCTTTATGGTCTTTCTCTTCCA ATGGCCTAAATGCTGATGTTCTTCAGTTTTCTATCTGTAGTCCTCATTTTTACTTGGTCT ATATTCTTCTAGGATGAAGTCTTCTACTCTTTTTGATTCATCTTTTGCAACAACGACCAC CACCACCCCAGCTCCAAATTTGTGTCTCCAGGATGACCTATCTCCTGTTCCATTAAATAG TTTTCCAACTAATAACAAAACAGCTGCAGAAGAACCTTGACAGTTCTAAAAGTCAATAGG TCCAAAAAACATTTCTCTCTCTCCTGACCAAACTCTTCCTCTTATCTTCTTTTCTCAATA AATTTCTTTATTATGCATCTAAATACCCCAAACAGGAAGCTTAGACTCTCTCTTATCCAT TCACATAACCTGTCTCCAAATCTTTTCCCTCCTTCCCTTCACCATTGTTCTAACCTCGTC CAAGTCCATTCTATTTGAGTATGGTCTCCTTACCTCCAGTCTGCCGTTTTTCTGGTCTAG ATTCACCTTCCTCTTCTCCTTTAAACACCACCCTCCTTCTAAGTCTTTGACAGCTTTCCA TTCCTTATTACTAAACTCCACTGTGGCACCTTCACAACCAGGTCACATTTGCCTTTCCCT TTGTGCATCCATCATTCCAGCCATAGCAGTCCATGCATCATTCACTAATGTGTCTTTCAG TTGGGCTTCAGGCAGAAAACTGAAACCATTTCTAGGTATTTCAACAGAGAGAATTTATTA AAAGAAATGGTTTAAAAAGTATTTGAAATTTTAAAGTGAGAACAGGATACTGAAGTAATT CCTGTGTTAAGTAAGCAGGAACCATCTATCACTCTGGGACTGAGGGATTACAGGAAAGAG GATTGAGTTATCAGAAAGTAAAAGTTTGGATAAAAGGGACCCCCACAGAGCTGAAACCTG CACCTCTAAGGTGGGGTAATGGCTGGCTGCTGCAGCTGCCTCTGAAATGCTGAGTAGAGC CTCCTTGGAGCTGAGGCTTAAACCTCTAGGGAAGGAGTGCCACCAGGCTGGTGTAGGAAC CTCTAACGGTGTGATGAAGCTGGTTATGAATAAAGCTCAACACTGGAACCACATGTTGCT GTTGATGTGAAGGGCCGTTGCTGGGCAGTACTGTTAGAGCACCATCAAACAGAGTCAAGG AAACAGGATCTTCCATGCCTCCTACTTTCTCTGCTCCCTCTAGTGCCCCCTGTTGGTGGG ATCCAGCAGACAACTTGCAGAGTTCTGGCCTCAACATCAGAAGGGTGGATTTAGAGTTAA AAGACAATTGCTTAATAACCAATACAGTACACTTTCACATCTCCTTGTCTTTACTGATGC AGTTTCCCCATTTATAATGGCTTTTCTACAAGTATCTGCCTGATGAATGCCTTTGCTCAA ATACAATCTCTTTTTTATAATCTCCCTTAATCTTCCCAAAAGTAATTATTTATACTATCA TGTGAGTTTCCCCAGTAATTTGTAAATACGTTTTTTGTAGATTTTTTTTATACTATATCA TAATATGTGTTTGTGTGTTTATTTTCCATTTATTTTCTGCCAAACCAGGTACTCCTTTAG GACAGTTAGTTACAACCATAAAATATAGCAGGGTGCCTGGCATACAACAGATATTGGTTA AGCTCAATGGAATTGATAAGGGCATTTTAATGACATTAATATTAGATCATTTCTTATAGA TATTTTATCATCCCAGCCAGATTTAAACTTCATAAGAGCAGAAATCATCCTTTATATTTC TTTTATTTTCTTTGCGGGGTTAAGTGCAAGGTTGAGCACACTGAAGAAGAGCTCAGTGAT ATTTGTTAACCACCTAGCTTGTTTATTAGCTACCACAATTTTGGTTCAAAATGACATGAA GATGGAGCATGATTATGAATATCAGGTAAGATCCATAATTAGGTTAGATGTGCTTCTAGC CCATGATTCCAACAGTTAGAGGGCACTGTATGTATGGTAAAGTTCTGTATTTGTTGGAGG ACTAACACAATCAAGAGACCAAATGTAATATGTTTTATAGTGAATTCTAAATAATGAAAT ATATTATAGGTTTTATTTTTCTCTATTGATCTCCTACAGAAAATATATCCTGCCAATCCA TGAGATTACTAATTCTGGGCTATATCTGTTCCTAGTATATTTATTAAATTTCTCACAACT ATTAAAATCAACTAGTAATTACTTAAATGCAGGAAAAATATTGAATTTTAACTTAATCAC CAGCTTCTTGAAAAAAGAAACCTCTGTTCAACAGCTGATTTATATTCACATCCAAGAAGA AGAAAAATAGCTTTTTTTTTCTAAAGGGGAGTGATATGTAATTAACTATTGATTTCTTCT CAATTATTCAAGGCAAGCAATTATCGATATTGATGGAACAGATATTTCCCTACCTCTAGT GCCCAAATGAAAGGAAATATCCCATTCAGCATTCTGCTGCCTGGAACAAGAAATGCTGAG GATCTTCAACTTTAGCTGAAAACAGTTATCTGGATCTGTTTATTCCATGTTGCCCCAATT AAACATATTTCTTCAAGTGCAAGCAAAATAAAATCCTGAAAACCTACATATGCTTTCCAA ATTAACTAAAGCCAAAAAACAAGAGCTTTTGTCAGTTTTGACCATGAGGCTAACCACCCT ACATGTGGACTTTGCTTCACAGCTACAGATCTTGACATTTTTAACCATGACTCATAAAAT AATGTGGTTCTAATATTATGATTTCTAAGCCACTCAATAAGAGGTAGCTTATATAATCAT TAGAAACCATGGAACACTGCCTTGCATATCAATATTTGGAGCCTGAAGGATTTAGTAGGC CTTAATAGTCACTTCTGACATTTACAGATAGCAAACGTGGATACATTTGAAAATTATGCC AATACACTACGCAACCGTGTTAGAGGTCACCAAGGAAATGTTGAGGAAGGCAGTAAAACA GTGGTCTATTTAGGGCACTCTGTTATTAACCATGTGGGTATCCACCACCATCTTTCCTAA GCTCATTGACACACAAAGCACTGGCATGTTTGTGTGTAAGAAGCTTCTTTTGAAGCTGAC ATGACTGTTGAACATAATTAGTGGACAAGGCAACATTCTCTATTGAGTTACTACTTGGAG GGTAGAGTTGTTTTCTTTTAATACTTTGCACTTAATAGTAATATTGGGTATGTGTATATG AGTGTGTAGTGTGTTGAACTCATGTGGCATCCCTGGGGAAATTTCACCATGACATTTTTA AAAATGGAAAATGTTACAATTTATAAAAAGCTACTTTTTCTGCTCTGTTCCCCACCTCCC ATTCCAGAGGGGTTCTATATATTAAATGCTTAAGCAGCATATGTTGCTTGGGAAATGTTC TTGGCTCTTTTACTCTTTGTTGTTGTTTTAATTTCCCTGGGTTCTAGTTAACATTCTGCT AAATCAGTGAAACAGTGATTATCTAAAAGAATAGGAGACATGGAATTAATGAGGTTAGTC AGAATTTTGAAGAAATAAGAAATTATTAGAGGTGAAAGTTACATGACAGGGTCTGTGAAT GAATTCTAGTCTCTGAAGTTGCTTGTCTTGATTTATTCAAACTGATTCCATTAATTGATG GACATAATGAAATTTTGGTAATCAGGGTTTCACCATCGCATTTATTACTATTCCCGGAAA TCAAGGTAACCTTGGGCTATACTTCCCATATTTACAAGGTGATAAAAATCCTTAATAGGC TGTCAGGGACGAATGTGACTGCTTTTCCTCACACTCCTCCCATGAAACAAGCTTTCTCTC TTCCCATCTGGCTGCCGCCTGCCTGGAGCATGCTACTTTCCCCGTGTCCCCACCCCTCCT CATCCCCATGCCTCCCGGTGGGTTCTGTCTTCATGCATGCAGCGCTGGAATCACGCACCG AGAGAATGGCCCACCCCTTAGAGGTTTTTGGTCATTTTAGCAATACCGCTTTGCATTTTA AATACCATTCATCTGGCTTCAAAGATCTGCACTCTTGCATCGGGCACTTGTCCTTTAAAA ACCCAAAAGATCACAACAGGTCCCAGTTCCATGAAGAAAAGATACTGCCAAACTAGGACT ATTGCATTACTTTGTATTCTATAGCCTGAAATGGACAATGATAACATCCAAGATTGCAGC AAAAATCTATATGAAAAGGACTAATATGATAAAAACAAAGGCAGAAAACTACATTTGTTT GGAAATTGGAGTCACGGGCTTCGTTTGTGGAGGGGAGGGGGGAGCACAAAGATCGATAGA GATTTTTTTTTTAGGCTGAAAACATGATGTACCAGATGAACTTCAATTGATTCTGCTTCT CCTCCCCGCGCCCACCCACCCCTACCTTCCCCCTCATTCTGCAGCGAATGTCTGCGACAA CGAGCTCCTGCACTGCCAGAACGGAGGGACGTGCCACAACAACGTGCGCTGCCTGTGCCC GGCCGCATACACGGGCATCCTCTGCGAGAAGCTGCGGTGCGAGGAGGCTGGCAGCTGCGG CTCCGACTCTGGCCAGGGCGCGCCCCCGCACGGCTCCCCAGCGCTGCTGCTGCTGACCAC GCTGCTGGGAACCGCCAGCCCCCTGGTGTTCTAGGTGTCACCTCCAGCCACACCGGACGG GCCTGTGCCGTGGGGAAGCAGACACAACCCAAACATTTGCTACTAACATAGGAAACACAC ACATACAGACACCCCCACTCAGACAGTGTACAAACTAAGAAGGCCTAACTGAACTAAGCC ATATTTATCACCCGTGGACAGCACATCCGAGTCAAGACTGTTAATTTCTGACTCCAGAGG AGTTGGCAGCTGTTGATATTATCACTGCAAATCACATTGCCAGCTGCAGAGCATATTGTG GATTGGAAAGGCTGCGACAGCCCCCCAAACAGGAAAGACAAAAAACAAACAAATCAACCG ACCTAAAAACATTGGCTACTCTAGCGTGGTGCGCCCTAGTACGACTCCGCCCAGTGTGTG GACCAACCAAATAGCATTCTTTGCTGTCAGGTGCATTGTGGGCATAAGGAAATCTGTTAC AAGCTGCCATATTGGCCTGCTTCCGTCCCTGAATCCCTTCCAACCTGTGCTTTAGTGAAC GTTGCTCTGTAACCCTTGTTGGTTGAAAGATTTCTTTGTCTGATGTTAGTGATGCACATG TGTAACAGCCCCCTCTAAAAGCGCAAGCCAGTCATACCCCTGTATATCTTAGCAGCACTG AGTCCAGTGCGAGCACACACCCACTATACAAGAGTGGCTATAGGAAAAAAGAAAGTGTAT CTATCCTTTTGTATTCAAATGAAGTTATTTTTCTTGAACTACTGTAATATGTAGATTTTT TGTATTATTGCCAATTTGTGTTACCAGACAATCTGTTAATGTATCTAATTCGAATCAGCA AAGACTGACATTTTATTTTGTCCTCTTTCGTTCTGTTTTGTTTCACTGTGCAGAGATTTC TCTGTAAGGGCAACGAACGTGCTGGCATCAAAGAATATCAGTTTACATATATAACAAGTG TAATAAGATTCCACCAAAGGACATTCTAAATGTTTTCTTGTTGCTTTAACACTGGAAGAT TTAAAGAATAAAAACTCCTGCATAAACGATTTCAGGAATTTGTATTGCAATTTCTTAAGA TGAAAGGAACAGCCACCAAGCAGTTTCACACTCACTTTACTGATTTCTGTGTGGACTGAG TACATTCAGCTGACGAATTTAGTTCCCAGGAAGATGGATTGATGTTCACTAGCTTGGACA ACTTCTGCAAAATATGAGACTATTTCCACTTGGGAAAAATTACAACAGCAAAAAAAAAAA AAAAAAAAAAAAAAAATCTAAGTGATTGCCAAGATTATGCCAAAGCCTGTTGGCAGAGTA CTAAGAGACTTTTATTTTTAAGTCATGCTATTTTCACAGATTGATGGTGATCATGTGACT CTAGGGATGCTGATCTATGTATCTTTCCAAATACAGTGTTTACATGGAGTATCACAAGAC GCAACCTGGGGAACCAGGAAGGGAGCAGGGAAATTGAGTGATTTGCAATTTGACTTTGAA TATATTCAGACTTAAGTATTTAGAGGAAATATCAAAATATAAAGCAGCAAGTAGACATAA CTGCTGTTCCTGAGAATAAAGTTTGTTTTAAGTGCTGCCCAAGGTGTAATAAATTCTTGT TTCTGCCTTTTATTAGGCCAATTACTGTGCAAGACAGCAAGGGGAGGCAGGTGGGGAAGA ACCTTTGCAAAGTTTCAAAGAGGCTAAGACAGTGTGCATTTCGTTCCCAGCACACTGTTG TCCTACAGATTACAAGTGTATTAGCAGCAGCATCTCCTGGAATCAAAAACAATTATCAGC CCGAACCAGAGTCTTAAGGACAATGAAATTCTACATGACTTGGTAGAACAATAACCTATG ATAGTGTAAGGTCAGAAACCTAGTTCCAGTCTGAATTCTTCACCCTGCTGCCACTCCTTG CTGAAACAGGGAAGGGGGGAGGAATGTCTCCTGATAAATAACCTGGGTAAAAACTAGATG AAGGAACAGCATGTCTTATTGGTTTTGTTCCCAGAAAAGCCAATTCGAAGAAGGCAATAA AAGGTAAACAGGTAATGCCTGTGCTGCCTGCCACCCCACGTCTAAGTCTATTGAATGTTT GTTATTCAAACCAACAGTCTCTTTTGATGTAAGAAATAAGGAAAGATGGAAATAAATTAG AGCTTAGGCTTAGTGCCAGAGTGGCCAACCAGAAATTGGAGATTTACGTTGGAAGCATAA ATAGAAAATTATATTTCAGGCTCACCAAAGAAACACATGAAAATGCTGATAACATAGGGA GTTTGAGATTATTTATAATGAGGTGGATTTCTGATATTAAAATTAGAGTTTAAGTTGTCT TATAGTTTATTAGCACAAACCAAAGGCAGCCCATGTTATTTCTGGCAAAGATGCACTTTA TCGTTATCTGCTCATGGCTTTGTCGCAACGCTCAGGAATCAGACACTGCACACTTCAATA GTTGGGATTCCAAAAGCTAATTCTAAAATTTAATGAAGGCCTGATTTAAACTGATTCATC TGCATTTTATCTTTATGAGGCCATAAGAATCTAAATTGATGAGGAATATCTTTCATTCCG TGTATTTAGATATAGTTTTCTGAATTTCCTGAAGCGATGTGATCTGCTTTTAATAAAAAT TCACTTTTAGGT bcftools-1.21/test/csq/ENST00000542803/ENST00000542803.fa.fai000066400000000000000000000000221467060157400215250ustar00rootroot000000000000001 343452 25 60 61 bcftools-1.21/test/csq/ENST00000542803/ENST00000542803.gff000066400000000000000000000062041467060157400211530ustar00rootroot000000000000001 ensembl_havana gene 1 343452 . + . ID=gene:ENSG00000162631;Name=NTNG1;biotype=protein_coding;description=netrin G1 [Source:HGNC Symbol%3BAcc:23319];gene_id=ENSG00000162631;logic_name=ensembl_havana_gene;version=14 1 ensembl_havana transcript 11 341464 . + . ID=transcript:ENST00000542803;Parent=gene:ENSG00000162631;Name=NTNG1-206;biotype=protein_coding;tag=basic;transcript_id=ENST00000542803;version=1 1 ensembl exon 11 193 . + . Parent=transcript:ENST00000542803;Name=ENSE00001711486;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001711486;rank=1;version=1 1 ensembl five_prime_UTR 11 193 . + . Parent=transcript:ENST00000542803 1 ensembl five_prime_UTR 8063 8587 . + . Parent=transcript:ENST00000542803 1 ensembl exon 8063 8833 . + . Parent=transcript:ENST00000542803;Name=ENSE00003594347;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003594347;rank=2;version=1 1 ensembl CDS 8588 8833 . + 0 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 184276 184916 . + . Parent=transcript:ENST00000542803;Name=ENSE00003471810;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003471810;rank=3;version=1 1 ensembl CDS 184276 184916 . + 0 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 255148 255324 . + . Parent=transcript:ENST00000542803;Name=ENSE00001451664;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001451664;rank=4;version=1 1 ensembl CDS 255148 255324 . + 1 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 255456 255472 . + . Parent=transcript:ENST00000542803;Name=ENSE00001620095;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001620095;rank=5;version=1 1 ensembl CDS 255456 255472 . + 1 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 263634 263639 . + . Parent=transcript:ENST00000542803;Name=ENSE00001659820;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001659820;rank=6;version=1 1 ensembl CDS 263634 263639 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 290744 290911 . + . Parent=transcript:ENST00000542803;Name=ENSE00001451661;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001451661;rank=7;version=1 1 ensembl CDS 290744 290911 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 296659 296793 . + . Parent=transcript:ENST00000542803;Name=ENSE00001451660;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001451660;rank=8;version=1 1 ensembl CDS 296659 296793 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl CDS 340605 340834 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 1 ensembl exon 340605 341464 . + . Parent=transcript:ENST00000542803;Name=ENSE00001595215;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001595215;rank=9;version=1 1 ensembl three_prime_UTR 340835 341464 . + . Parent=transcript:ENST00000542803 bcftools-1.21/test/csq/ENST00000542803/splice-region.txt000066400000000000000000000004051467060157400221460ustar00rootroot00000000000000263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding 263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding bcftools-1.21/test/csq/ENST00000542803/splice-region.txt-l000066400000000000000000000004051467060157400223770ustar00rootroot00000000000000263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding 263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding bcftools-1.21/test/csq/ENST00000542803/splice-region.vcf000066400000000000000000000006131467060157400221060ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 263634 . G A . . EXP=missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding;type=ENST00000542803:107946262-G-A bcftools-1.21/test/csq/ENST00000543077/000077500000000000000000000000001467060157400166525ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000543077/ENST00000543077.fa000066400000000000000000000425561467060157400210210ustar00rootroot00000000000000>12 12:4537321-4554780 TTCCAAGAGAACATAGATTTATTTGGAACCCAGAGTTGCTCGACTGAAGGCACATTGGGA TCACCCCCAGAGATGGCATGAAAGGGGCGAGAGAGTGGGGATGGCCACAGCAGGAACGTG GCACGGAGATGACAGGGCTGATGACGGGAAGCTCAGGAAGGGGCAGTGTGAAGGGAGGGA GGAAACTCGGGAGGCTGTGGGGTCCTCCTGACGTAAACTCTCCAGTCATCTTCTTTCTTT TTATTTAACCTATAAAAAGATGGCATAATTTATAGTCTCTCCCAGCTCAAATGTCCTGCC ATCCCAGTCATCCTACTAGATGGGTTCTTCAACGTCAGACCCACCTGGGATGTGTATTAA ACGTGTAGACTCCTGGGCATCGTCAGAAAATCTGGGAGCGGGACTTGGAGATCTATGTCT TAACGTGCTCTTGGGTGATTTTTTGTAATGCAAGTTAATGAGAGCATGGGGACTGCATCT ACCTTGTTCACATGTGTATCCCAGAAACCTAGCCTAGTCCGGGGCAGGGTTGAGGAACTC AGTATATCTTGATGGGTGAATAAATGAATGAATGAACTCTATAGTCACAGAATGTGTATA TTTGGTTTTGACCAAGGCAGAAAAGGAAGAGGGATGCTGCCTCGCTATAGTCTTCCATCG CTGTCTTCACCCTCCTGGGCCAATTTCCCCATTGGCAAGCTACAGGGTAGTTGGACTGAG TACGCCACAGGACTTCTTCCTGCCTTAATAATCAAGAGCACCATGAATCGGTGCTTTCGG GTTCTCTTTGCCTGCCTTCCTGCAAGGGGGGAAAGAATCAAGAGGAAAATCAACGGCAAC CCAGAGATTTGTTGTCAGTTTTAATAGGAGGAGTGGAGTCAAAGAGTTTAGAGAAATGTA GAAAAAGACCTTTTACTTTTTGCTGGAACATGATATGGTTTGTGCATGGCACATACATAT TTAAAAAAAAGACGTATCACATTTCACAACCACATGACCGAACAGCATCTGGGTTGTGCT ATGCGCTGTGCCTAGGCTGGAGGGCAGCTCTACCCTGGGACCAGCCTGAGGTACTCAGCG ATTTACAGAAAGAGGAAACCACGCAGGACACAGCTCTCTGGTGCCGGAATTTCAGTCGTT CAATGAGGTATACAAACATGGTTCTGCGTTGGCTATCTGCATGATGGACCAGATTCAGGA CCTGCTTGGGGCATAATCGCATCCTCCACCTGTTCTGGGAAGAGGAAGCATCAACTCAGA TGTGAGCAGAGACTGGAGTATTTCTCTCTATTCTTCTGGCCTTGTCCCAAACATTCCTCT CTTTGGAGTTTTGCAGGGAGGTAGCAGAATGAGTGGCTGGTTCCTTCAGGGGACGAGCAA GTATTAGAGACCCACTTTGTAGACACAGGCATGGTAAGTGGCAGAGAATGCTTCCTCAGT GACAGCTGACCCAGAGTCTTTGAGGAAAAACATTGGGATAGAAGGATGAAGGAGTTTTCT TTTTTTATTTTTATTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTG GTGCAACCTTGGCTCACTACAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAG CCTCCCGAGTAGCTGGGACTACAGGTGCCCGCCACCAGGCCCAGCTATTTTTTTTTTTTG TATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGGTAGTCTCGATCTCCTGACCT CGTGATCCGCCCATCTCAGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCGCTAC CTGGCCAATGAAGTTTTCTAGCTTGTGTCCACATGAAAGGGACAGAAGGAGATAGAGGGC AGAGGGGAGATCCTCGTGTCTTGGAGGACATTTGTAGATGTGCATTTTAGTAGATATGTT TGCACCAGTGACTGTGGCACAGAATGGGCAAAGGCAGTGGACAAGGGGAGAAAGGAGAAC TATAGCTCATGGACTCTCCTATTTCTTTTTTCTCTCAGGACTTGCATAGAACAAGAACTT GAAGGGTCTGAGGTCTAGGACAAGAAAGTGGCCCAGAGCCAGCGTTGAAGGAGAATTGCA AACTGCCCAGGACAGGATGAGGTCTGGAGAGAATTTCAGGCCTGGGTTTCTGGGCAGGAG AGGTATCTGTATGTCTAAAGAGGAGAGAGGTTTGGCCGGGTGCAGTGGGTCACGCCTGTA ATCCCAGAACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCATC CTGGCTAGCACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGATGTGGT GGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGTGTGGACCCT GGAGGCAGAGGTTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAG CGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAGAGGAGAGAGGTTTGTACCCTGAATCAG AAGGCAGAAGAAAATGTTCTTTTTGTTAGGCCATAGACTGGCCCTGACCAAGGGCTTGGC ATGTGTATTAGGGCACTGTGGGATGTGGCAGCAGAGGGGAAGGCTGTGGAGGATGATGGT AGGGTATGAATTAGAAAATTACATGCTGCTTTCCCGAGAGGTTCAAAAATGTATGGGAAG TGGGAAGGGAAGGGGTGTTACAAGGCAGTGAATGATGAAACAAACATAATCAACAGCTTG AACAAGGCATTTGGAGTTTTCTGGTTTCCTATGAGGTTCATCCATTGCCCTGAAACGGGT GGAGGTTTTACAAGGAGCCCGAGGCTGCCCCATTGCTTCTAAGCTAACCTCTAAGGCTGC AGCTGAGAAGTGCATCTTGAAGAGTGTGCAGATATGCTGCTCTCCTCTTTATTATTTGCT CTTGAAGAGAGAATAAAACAGCCTCTTGGCCCTTGGAACTCCAAGTTTGCATGGAGCTGC CAAAGAAGATTCAGGACGAAAGAGAGGTGAATTAGCTACAAAACTCTATAAACCAGGCTC ATTGCTCAGCACTTGGGGGATGGAGGGCCCAAGTCTCAGTACATCCTCAGTGGGAAAGTG GGGTACACTCTGGCTCCCCTGCATATAGCAGTGCCTTCTGCAGCCTTTGGGAGCCAATGG GCCTGACAACTGAATTCAGGACTCAGTGGACATGTGACCAGATAGGAAACAACTCTCCAT GCCCGGGCACAGAAACGGAAGCTGGAGAGAAGGGGCTGAAATGCATCCTGCTGATCTTAT TCTGGTCTTGTCCCTTAGCTCACTTCTGTAGATGGGGATTGACTTTTCTTAAGTCTAAGT CACTTACAGGAAAACAGAAAGCCCTTGAGAGAATTCCTTTGCATGGGAAGGATTTTAAAG AGTCACCCACACATACCTGCATCCAAAGGTGGTATTCAAAATACTTAGCAACCAGCTAGG TGTCGTGGCTCATGCCTGTAATTCCAACAGTTTGGGAGGCTGAGGCGAGTGGATTGCTTG AGCACAGGCGTTCAAGACCAGCCTGGCCAATATGGCAAAACCCTATCTCTCCAAAAATAA ATATAAAATTAGCTGGACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGAAGGAGAATCGC TTGAGCCTGGGAGGTGGAGGTTACAGTGAGCCGAGATCACACTACTGCACTCCAGCCCGG GTGACAGAGCGAGACCCTGTCATAAACAAACAAACAAACAACCCCCAAATACTTAGCAAT TGATACAGCATGGGCCCTGGTACCAGTTAGACAGACACCCAGCCCCTCCTAACCGGTGCG GGTGCAACTGCTATGCAGTGGCTCAATATCATGCGTGCTTGATCATAGGCATTTCGTAGC TTCTGCTTCCCACTCCTAGCATGAAAAATGAAAGTGGACATTTGGGGAAATGCCTTGCCA GGATTTGAGCAAGGTTATGATCCTCTAGAGAGATGAAGGACAAGGCTGGCAGCCCAAGGC TTTGGAGACTCTCTTGAAGATGGCTCCTTTCCTGCCACGTGAGCTGAAAGATCTTGGAAA AAAGGAAAGCATGCTATGGGACCTAAAACTTCCTTCTCCTTTTTTCTCTGGATCACAGTC ACGCCGTCCGCCAGCCATCCCACATTCCAAGCTCCACTAGGAACTGATATGCACCTCAGG TTTGGAGTGCCTGCATTTCTGATGGACCCTGTTCAAGAGACTGATTGCACTGGACAAGAC TCCCTAAAAAACAGTGGAGAGCTTTATCCCCGCCTCCAAGCAGACCCACACTTCAACATT CCACGGAATCAAGATGGACCAGTTTTCTCCCTTTTCTACAACATCCAAGGGTTGGCCATG TGCACACGTGTTCCGAGGCTTCTACAGTCTCTTCCATCTTCATGTACCTGGGTGTGGCCT TTTCTTCCTCACCCAGCACATGTCCTCCCTGACATTTGCAGGGCAGAGGAGGTGGCAGGT AAGGTGTCTCCCCCTTCGATTGCCAACCTCCCATCTTCAGCTCAGAATCCCTCAACCCAG ATCTATCTATAGATGGATGCAACTGCAAATAGCGAGGTATGTTGAAGATGAAGGTATTTG CAACAGATGAAGGATTGTCTTGCAGGCCGGGGCCCCCAAGAGTCGCAGAGGTCATCAGGT CATTTTGTAACTCCATGGTTCACATATGCCAAAAATATTTGCACTCTGATATGGCTCTCT CTGGTTTCAGATTTAGGAACATTCCAATGGTTCAGGAATCTGAAGGCTCCGGGCAGACAA CATTTATAGTCACTTGGGGAACCTCTGCTTTAAATATTCTCAAAGGACAGGAGGCAGAAG GCACTGTGCAGCAAGGAGCTGCTTCAGCTTGGCTGCTTGACTCTGTGGGATTATCACTCC TCTTCTACTGCAGGGAGGAAGAGAGCACAAACTCTGGAGGTCACGGTGCCCATTCTGCTG CATCCAGGCACAGCGCGTATGTGAGATGAGGATGAGCAAGAAGGAAGTGAGGGTATCAGA TGAGAACTTGGGTGCGTTTCTTGGACATAGTTGGAGAGGAATTACCATCTGTAGTCCAAA GCCTCTCTACTTCCTTCATGCCCTATTTTGTCCCCCTACTCCTCGCCAAAGAGGTTGCCA TTATTAGGATCCTTGTCATCTGAGGTTAAAATAAGACCAGTTCAAAGTGAGGAAACGTTA TGGGCAGGCAGCCTGGCCCCTGCTTGTTCCTGGAGCCATGCACAGCCTGAGTTCTCCAGG CAGAGTGGCTCTCCTAGAACATCCAGTCCCTTCTGCTGCCTCCACAAGCCTTCCTCAGCT GCCCTAGATGCTGCTCTACCCCTTTCCTCCAAGAAGGGAACCGCTTCTCCCCCAGCCTCC CTGACAGTTCATCCCAGTGTCCCCAGAGCCCTCTCTGGCAGGAAGCTTGAAGTGCCTGAT CACTCTCTTTCTGGTTTGCAGTTCAGCCTCACACCCTCTCACTCTGCCGTCTCTGCACTT TGAGGACAGCTGCTCCCTGCTGACCTATGCAACCCATGTAGTTAGTGGCCTCTGAATGGA AAGATGATTGGAAAGAGGCAGAATGGGAGCACACATCAATCTTGCTGGTTTGACAAGTGA CATTCTTACAGGCAGATTCCTGCAGCGATGATGCTAGGAGAAAGAAACCTGATGCTTTGA AATGCCATTGCTCTGAGAATGTGTATAAAGCTGTATGGATATACAACAATGCACACAAAC TCCTACCCTGGCCTTTTCCTATGCACATGGTCACATTCCACAAGTGTCACCGATACCTTC TCTCCTCGAGGGAGGTCAGAGCATGGGATAAATTGCCATTCTAAAATTGCTGATTTTAGC CCTCGTTTGAATGGGCTACATGCCGTGGGGTCCAGTGGCCAAGGAAAACAACTGAGGTCT CCCCAAGCACAGGATAAGCCTGATTCAGAAGCCATGGAGGGCAAGGGGAATTCTTCGCTG GTGCAAAATTTCAATCGAACAGATGATGCTTTAAATCTGTGAGCCTTCTTTTGTGGGTCC TTAGATCCTGGGAAGGAAATGAGTGACAGTCATGATCGGGGACACCTTGCTGCCCCGCTT TACCCGTCCGTATTTGCTCAGGGCAATGTAGGTCCCTTGGTACAAGTCTGACTCGTAGGC ATTGTAATTGTTGGGCAGGAGGGTTTCTCTGAACTTGCATTCTTCTTGGAAGCTGGGCTG TGGAAGACATGGGCAAACAGCAGAGACTGGGTTACAAATGAGGAGTGCTGCAGATGCCAG CTGGGCCGCAGAGAGTAGGCCCCTCTGCCAGGTGCCCTTCCCTTCTCTTTGTGAGACAAC CACCGTGAGGTCTGAGCATCCTGGGTGAACAGAATGGTGAAAGGTTAGGATGGGAAGAGG CTGCAGGCTCTCATGGTTTCCTCTCACCTTCCCTCCTTTACGATAAGGAAACCAAGGCCC AGGGACACAGGGGATGGTCTGTGCCACATGGGGTAGAGCTGAGGCTCTACCACTCAGGTG TCCTGACTTCCAGAGTAGTTTCTACTAAGTCCCTAGATGGTAACTTATTCCATTCAAAGA ACAGACCAGGAAATGACACAAGCTGTTTTCTCAAGTCCACTCTGAGAGGGAGTCTACTGG AGCAGGGATGAGAGCTCAGGGTGCTATTTCGTGACTTTTCTACTTCCTAATTGTGTGACC TTGGGCAGGTTCCTCCCCTTGCAGCCTCAGTTCTCTTTTCTGCAGACTGTGTGTGGTGGG GGAAGAAGGAGAGAGGCGGTTGGTGGAGGGGGAGGAGACACAAGTGATCTCTTAAGCCCT TTCCAGCACTGCCTGTCTCTTTGTTTCTGCTTGTGGTTCCTCAGTCTGTCTTTCCTGGTT TAAGTCTCAAGTTTTCTATCCCTCAAAAAGGCCCATTCTCAGTTTTGACTTTGAGTCTAG AAGAGGTCTGGTACCTCCTAGACCAGGGGTCCCCGACCCCCAGGCTGCAGACCCATACCA GTCAGCGGCCCATACCCGTGCGGGACCTGGGCTGTACAGCAGGAGGTGAGCGGTGGGTGA GCGAAGCTTCATTTGTTTTCCAGCCACTCCCTATTGCCTGCAAGACCACCTGAGCTCCAC CTCCTGTCAGATCAGCAGTGGCATTAGATTCTCATAGGAGCAAGAACCCTGTTGTGAACT TTGCATGTGAGGGATCTGGGTTGCCTGCTCCTTCTGAGAATCTAACTAATGCCTGATGAT CTGAGGTGGAACAGTTTCATCCCCAAACCGTCCCCCCATGTCCCCATCACTCACCCTGTC CATGGAAATAGTCTTCCATGAAACTGGTCCCTGGTGCCAAAAAGGCTGGGGACTGCTGTC CAAGACAATCATAGTTCTCCAGGGACATGCAGGAACAGAAATGGTGAGGAGCAGGAATTT TTATGGGGAAAAGGACCTGGTTCCCAATGTGACAGGTGAGGCCAAGGAGCCTGGGACCAA CAAAAAAATGGCCCTTTCCATGCTAATTTTGTAGAGTGTGTGTGGACCACCTGTTCAGAA CATGAACGCTGGACTTCCTGTCACATGAACACTGGACTTCCTGTCACATGAACGCTGGAC TTCCTGTCTCGCATGCACAGATTCATTCCCAGTACATCACCCCAAGTCCTCCTCTTTCCT CTGCAACCTGCCTGGGTGGCTGCCCTAAGGGAGTATGCGGGGATTTCCTGCTCTTGTGGG GAAGCAGCTGGGTCGGGGCTAGAAGAACAGAGAGCGAGGTGGGAGCCAGAGACCCGGGAT CTACTCTTGAAAAGAAATATAGAATGAGAAATGGATGGAGGATAACTTCTGACTCCTTCT TGCTTGAGTATAAAAAAAAACCCGCTCGATGGCTACTGGGCTGTGCCAGAGGTGTCCTCT GACCTTCTGTAAAGGAATCGTACTGCTAGTGTCCCATCTTGCTGGCAGTGTAGCTGGACG AGAACCTCTTGCTGTTCTGAAGGGCTGGTTAGTAGCTTGCTCCTCAGGGCCCCAAGACTC CCAGAGCCCTTTCAGTGGACCTCTCTGGCAACATTTAGAACAGCCATACTTTCTTTCCCA ATAGACTCCAAGATCCCTGAGATGAGGACTGTGTCTTGCTTGGTACATGATGCTGAGTGG ATGGTGGTTTAATAGCGACAACATGGCTGGTTTCAGTGGCTCACACCTGTAATCCAGTAC TTTGGGAGGCCAAGGCAGGAGGATCACTTGAGCCCAGGAGTTTGAGAGGAACCTAGGCAA CATAGCAAGACCTTGTCTCTACAAAAGCTTAAAAAAAAAAAAAAGGCAGGTATGATGGCG CATGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGTGGGAGAACCGCTTGAGGTCGAGGC TGCAGTGAGCCATGATTGCTCCGCCGCACTCCAGCCTGGGTGACAGAGTGAGGCCCTGTC TCAAGAATAAATAAATAAGTAAATAAGGACAGCACAGAAACATAAGGAGACCCCTGCATG GGTGGCTCTTTCAATGTGATGTGAGCGTGGGTGAGGGGACAGCCTTGCCTATGGGAACAC GGTGAAACTGCCCTCATATGTTTTCCCCATCTTCTTCTCTCATGCTTGCAGCTTATTTAC AAAGCACTTTCACTGATGTTAACTTGCTTGAGATAAATGTGAAGGCGTTCACTAGCCATG TCAACAGGTTAATGCCACACCGGGGGGTGGGTTTTTCATAAGCTTTCCTGTTTTCCTCGT TAGGATGCTCAGTGAATATTTGTGGAATGGATGAATGAAGGGATGTCTTAAAGGTAAAAA GGATGAACTAATCAATGTAGGTCAAGAACATATTTGTGCCACAGCTTTAAGGTTAGACTG ATGACAATAGCCTCTTAGCTACGTGAGCCTGGGGAAATCATTTAACCTCTAAAGCTTCAA TTCCCTCATCTGTGAAGTAAGAACAGTAAGAAAAATTGTGTCATAGAACTGGAGTAAGCA TTAATTGAAATTATGCATGGAAAGTCCTGGGAACAATGCTTGCTATACAGTAGAATTAAA AACAAATTAGTAGTACTAGTATTCTTCTCCAAGTAAATAATGAACTACTTTACATTAAAA GCCTCGAAAGACTGCCTTACCCTGGATCACCAGTCCCATAAGACTTGCTGGGGGTTACTG GACAATTTAGCTTTTAAGCTCTGCGGTTTTTGATGGAGTGCCTGGGAGACAGTAAGCTTG CATGGAAGAGCAGGAAGCCAGAGGAAGGGCAGAGGCTGACGCTGGCTCTGAACCAAGACC CCTCATTAGGAGCCTCTCTGGACCCTGGTTTCCTGCCCTGTGCACAGGACTTCAGTCGTT GGTGGGCAAGCTTGGGAGCAGCAGCACCAGGAAAAATTCAGCTCAGAACTGATTGAAACA TTCCAAGTAAAGCTACACTAATGAGAAGTCCAGTACAGGTCAATGAACAACATAGAGTCC AGCAGTAGATCCCAACACATACATGGATGTAAAATGAAATTAATCTGAAATGAATATAAA GTAAAAGTGTTATTTTAAATCACTAGAGAAAACATGGTGTTGGAACAACTGAATGGTATT TTATTATAATGATAATAAAGTTTGATGTGTATGACTTTATCCCTTACATCAAAATAAATT CCAAAGGGAGTAAAGATTCAAATGTAAAAAAAAAAGAACCATTAAAATCCAGAAAAAGTT TTTTTTAATAAACTCAGAATCAGGAACATCTTTCTAATCAGGACAAAAAAAATTAAAACC ATTTTTAAAAAGTAATAAATTGTCTTCTACTTGAAAAATATTACCTTAAAAGAAGAACAG AAATGGTAAACTGGATGAAAATACATACAATACACATATGTCAAAGAATACATTTTGTTA CTATATTCAGAACCCTAAACTCACTGGAGAATGAACAGCATTTATAAAACAGAAAATTCC CAGGAAAAGAACTATCAATGGCATTTGAGCAGAAGAGAATATGCCTAATAAGAGAAATGT AAGTTATAACTGTGAGATCCCATTTTTAGTGGCCAGATTTCAAAGAGAAAAGCGTTTGAC ACTATGCTCTCATTAGTGAGGGCACAGAAACTAGGAATTCTCATTTAATGTCCTCTGATG TGTATACTGTTATAATCTCTATAAAGAGCAATTTGGCAGCATCTACCAGAATAAAGGATG AATATAGCAACTGATCAGCAATTCCACTCCTAGAAATTTATCTTACTGATATATTCCCAC ACACGCACAAAAGTTACTACAGCATTAAATAACAAAAGACCAAAAACAATGTATCTATTA AGAGAGGAGTAGCTGAGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTG GGTGGATCACGAGGTCAGGAGATTGAGACCATCCTGGTCAACATGGTGAAACCGCATCTC TACCAAAATACAAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTACTTG GGAGGCTAAGGCAGGGGAATCTCTTGGACCGGGGAGGTGGAGATTGCAGTGGGCCAAGAC CGCACTCCAGCCTGGTGACAGAGCGAGACTCTATCTCAAAAAAAAAAAAAAAAAAAAAAA AAAAGAGGAGTAACTAACTCAATTATGGTAGATCCACATGATGGAATTCTATAAGCCTTG AAAAGATAAGAAGCCTCTCTGTAATGACATGAAATGGCCTCAAAGATACATTGCTAAGTG AAGACACAAGGTTTGAAAAAGTGTTGGCATAGTACGCTCTTGTTTGTGTGATTTTTTAAA AAAGATGATACCGGTGCGTGCACGTGTGCGTTAGCTATTTCTGGAACGATATACTGGAAT GAAACACTGGTAACTGGGGCTGCCTCTAGGGAGGAACTCAGTGGCTTCAAGACAATGGTG GGAGTGAGACTTTCCATAGAATATTCTTTGATACTTTTTTCTCCTTAAAACATGTTCCTG TGTTACCTAGTCAAGTACGTAAATTATTTAAAGTGGGAAGGGAATTTAGGGTAGCAAATG GGCCAGGAAACGAAGCGAGAAAACATTTTGATCAGAAACTGGTGGTCTCCTTCTTGTTGG GTCACGGCCCCTCTCCACCCACCAGCCTCCCCCCTGTTCTAACTTTGTATGTCCCTGGAG AGTAACCCGCCCAGTCAGTTCCAGAGAATTTATTTCTGATCTGGATGGTGGTTAAGGGAG AGGTTTCGTGTGTTGTTTGCAAGCTCTAGTGAGGAAATGAAATCTTGAGGTGGAGGAAGG GGAAGTGGGAGGAACTGAGTGACTTGGACAAGAAACTCTCAAGCCATTGCCCACTTCCCC GTGCCTAGAATGTGCCCATTTGAGAACCCAGCCTCTCCTAAACATCTGGATCTCCTAAAA CATGATTGTTTAAGCATGCATGACCATGGATGCGTAGATTGTACTTTGCTTCTCTGGTCA TTCGATTTTGGATCATTCAAATCCACTCCCCCTCAACATACACACTTTTTTTTTTTCTGT TTCTATTTTTTTTTCAAGTTTACTACTTTTTTTTCTTTCCATTCTGCCCTTTTCTCTAGC CTGTCTCATATCCCTGGCCTTCCCCAGAATCCTGTACAAAACTAAAGTGAAAAAAGACAA CTAGTAGAGGAAGCTTGTGTTAGAAGCCCTAACCTTCCCCTTGCTGCTCTCTCTCCTCCG CCCTCAGCACCCACATCTGTGGGGTTTGGAAGGCCAGGAGGCCTGTGGCATGAAGGAGAG ATAGTGCATTTTTTCTGAATGCTTCAGGCTGATGGGATTTTCCCGATGCCCAGAGTGATG CTCAAGACCCAGCCCCTTAATTCATCTTCATCAGAGCCCTGAGCTTTGAGTTCTCATGGC TTGGGAATGTTGGCCCCTCAGCTCTGGTGAAGAACGCACTCGAGCCAAGTGAACGCCATG TTCATAAAAGCAGCTACTGTATATGATTACTTGAATAAATGAAAATCATTCCACTGGGTC ACATTTCCTGGGCCTGCCAGGCTCAAGCCCCAGCATGAAAATATCTTCAATTTGATGTAG GTCTATTCAGACTTATGTGCATTTGGCACTCACTATGGAGAAGGGCATTTCTCAGAGGAG CAAGCATATCCATGGGGTAGAGGTGCCTCCAAAGTGTGAGGTGGACAAGACAGCCACCCT CTCGCCTTTAGAGCTAAGTCACTTGGACCAACGAGGATCTAATCCTGCTTTTAAACATCT TCACCCTGTGACCGCTGGGGCCATTTGTCCCTGTTCCTCCTGGCAGTGTGTGTTGGATGG AGAAGGATGGGGTGGAAGGATGTGGGCAAGAAGGAAAAATAAACCAATTCTTTGTCCTAA GACTTTCTTCTGTAGCCCCTGACTGCTTCTTTTCCTGTCTTTAGCTGAAATATCATCAGC TCTGAAGATGCCTGCATTTTCCAACCCTTTTTCCTAGCACACAATTGAACTGTTGATTTA GGAATGTTGGAAAGTGTTTTCATCAGGTGTTTCATTCTTCTCACTCCAGTGCAGCTCTTT GTAGCAGGCGGGGATTTGTATGCAGAGCCTCAGGCCCTGCATAAGGGCATGCACCTCCCG CTGCTCTCCAGCCCCATCTCCCAGCACTTCCTCATGGTGGGTGTCCTTCATCCCATTCCC TCAGGAGTGCTGTTTTCTGCTACAGTGGCAGCTGAGCCAAGGCAAGGCTGGTCCTCCCAG CCTTGTAATGCCCCAGATAATAATGTAATGCCCCAGATAATAATGCAATGCCCCAGATAA TAATGCCCCAATGTAATGCCCCAGATAATAATCAAAGGTCTCTGGAGGAAATCAATTTTG TCCTTTGCACATTGTCATACTGTTGACGAAAAGCATGTAAATGCGGCTCTTCTTAGTAAA ACTGAAATCACTTGAAAGCACGACCGAATTGCTGGTATCTTTTTACTAGTATATATTTTT CTCAACCAAAGGATTCTAATAGAACCACTGTCAGGTGGAGATCCTTGATATTTTGTTTTC TGAATTTCAAAGGGGACCAAGGGGGCTAGAATTCACTGATTTCTGCCTCATCCTCAGAGA GCAGAGATCCAGGCCCAGAGAAGTTCAGTGACGTTGCCCAAAGTAAGACGAGTAGCTGGA GGGTAGGTTGGCCAGGAACTGGAACTCGGGTCGCGGAGCCCTGAGACGGGGCTGCACACA GCTGTGGCTGGACGTGTGACCCTGGAGACCGGGTGTCCGCAGCTGCACAGGGAGGATGAA GATCAAATGCACCTCCTAGGGGTGCTGTGAGATCATGCTCGTGAAGCCCTCTGCAGCCTG TGAATCCGAGCACAAGCAGTAGGCTAGTGCTCAGGGCAGGGCAGCTGTTTATATTGTCTA AAGGGGGGCCTGGCAAACTGCCCTGAGCCTCCACACCCCTCTTTCCAGGAGACAGACATG TGTGAAGCCACTTCTAGCCAGGTTTCCTTGGCCCTTGTTCTCTGCCCACGAGTCGTTGCC TTGTCCCCCTCACCAACACCTCAGCCCCAGCCCAGTTTCCCTCCCCCACCCATGAGAAAT CCCATGAACTGGCAGTAGCAGCTGAGCCTGGGAGATGAGGCAGCTCCGGGGGCTTAAAAG GAAATAGTGTGAATGAAATCATCACCCAGCAGGAGTCTTCCTGGCTCCGGGGATCAGTTG GCAATTGTTTTTTTAGACTGTGATAACGGCCTCTGAGGGGCGGAGAGGGAGGGGTAGAAG TTGCTCAGGAGCATCTGGTCCTGAGCCACACAAAACGTCAGGTGCCCCAGGCTTGGGGCA CAGCTGTCCAGCCCCACTCTCTGTGTGCAGGCCCGGCTGGCCCTGAGGTCCAGGGAGGAG AATCTCCCTCCCTGGAGAAGATGCTCTTTGGCCAAATGCTACTGAGGGTGAAGGTAGGAG GGGTGGGAGGGTGGAGGTGAAGGGCGCCGGGTCTTTTCCCAGAAGTCTTCCTTTCTCCTG GACTCTGCTTGTTTAGTAAGCCCAGCAGTTCATCAACCTGCCTAACCCCCTTTGAAGTCA TCAGCCAGTAACGGTGCTGCAGAGTGAGGGCTGGGGGTGGGGTGGTGGGTTTCAGGCATT AGGAGTCAGCCTCCTTTCCTTTTTGCTATTCTGAATGCTCTTCCCCGCTTTGTGGCGCTT TCTCTGATGGTTAAATCGTATATTCCCTTCCCGAGCCTTTCCCAGCTTCTCCTTCCAGGG CCAAGAGATTGAAAGTGGGAAGTGGGTAAATTTCCTCTATATTTGTGCATTTTCTCCTCC CCACAATTAAATTCCTTTCTGGGTAGGAAGAAAAAAGTAATAAATGGTTTGTTGATAAAG GCGACAAGGAGAAAGAAGAGTTTATGAAATTTGTGCTTTCTCCCAGGAGATTTACTTGCT AAAACGTCCCTTGCTTGCATGGAGTCCCACAGCCAACAGCCTAAATTCCCGGCTCTCCCG ACCCTATGGGCTTCCGGGCATTATGCAGGCTGGGAAGAAGGGGTTCTTTGGGATGCCCCA CCCTACAGAGGGGAAACCTGCTCCATCAAAACCTGGGTTGGTCCCAGGCCTCTTCCTGTC CTCGCCATCACTTTCCCAGAGAGCGGTAACAAGGATATGTCTCTTCTGTCTCATCTCACT CGCCCTCCAGCTTTCAGGTTCAGTGTAACATGGGGAGTGGGTGGTCCCCTGCCCTCCAGA GGCCATGTAGCCTGCTGACCCCCAAGCCTGCCTGTTCCTCAGAAACACCTGGCAAATTTA AAATACAAAAACAAATGGATTTCCAGGCCCACACGCCAGCTCTGCTGAATAAGAATCTCC TAGGTAGGTACCTGGAAATCCATACTTTTAATAAGTTTCCAAGGTGACAGAGATGCAAAC TGTCCACAGACCCGTGTGGGAGACCCACTGATTGTAGTGCATGCCGTATGTCCACATAAA CCAACCCAGACTGAGAGATGTTAGCACTAAAGATTATGGGGTGGAGGCCACCTGGTGAAC CCGTTCTTGTATTTCATAGACCTCCTCTGTTGGGACAGCTCCCCTGGGACCCAGTGCCAG TCCTGGATCTATTTCTTCACATCCCAGTCCTCAGTTTATCCTCCAAGGGGCAGTAGATCA GCTCTCCACACCCTCCCCATAAATAACTTTGATATTTTTTGAGGCCTGCTCTGAGGTCTT CCTTTTTAGCTTGCTTATTTCTGTCAAAGGAACTCTCCATTTCTTCAGCCTCATCGGGAT GTTTGCCCCGCCATATTTTGGAATAAGCCAAATGATGGGCCGAGGGCTGCAGGAAAGAGT AGGTCAGTGAGAGCAGAGGTTTTCGTCAATGTGCTTAGAAGCTGGTTGCATTAACCCAAG TGCCAGCATTGGCACTCCCAGAGGTGACCTATGGGGGTGGGGATGGGAATGGGTGGGACT GGTACCAGCCTAAAGTGTATAACGGGTAGGCTGCTTCTCTAGCGTACGTGATCGGAGACC AGAGGATTGAAAACCCTAGTGCAGAATCTCAGCACACTGATGAGGATGAAAATAGCCTCC CATTCCACTCCTCCTGCTGCGCACGAGGCTGGGGCATCTTGCAGGGCGCGTGTCATGGAG CAGCGCACCCAGGCAGAGAGACAGACTTGCTCTCGGGGCCTCGCCAGTGCAGGGAATCAC ACCTGCTCACAAGCCTGGATGCCAGAATGTGGGTTTCCCTCTGGCCCACGGGCTCCCTGA GCTGTGGTTTCCGTTTAAGCACACGGGCTCCGGCCGGCAGGTGGGAACAGAAGAAGCACG GGCCAGGGCAGAGGACAATCACCCGTGAGGCTGAAGAAGCACAAGCTGCAAGGCCCCTCC CTTTCACAGGCTCCTCTCACAGCCTTTCCTTTCCCATTTAGATAGTCACTTCTCTACTCA GGACTTCATATTATTTTCTTCAACTGTGTAAGCATCAAGCCTTGTAAACCTGGCACTTCC CCGGCCTGGTGAACTCACCGTTGCGTACAATCTTCCTTTACTGTTCATGGCAACGAAGAG GGCACTTCTCACTCCAAAGAGACTCACCACGCCTCGCTCCACAGTGGAAATTTCCAGCAG GCCTGACAAGGAAAGGGGGGCCACATTACCTAAGGCTTGTGCAAATCAGAGTGGGAACTT GAGCCGACAAGGGCATCTCAGTCCATCCCCCTTCTCCTAGAAAGCCAGACTCTCCATTGC CCCATCCATGATCCCTCTAACTCTAGGAGACCCTGGCTGCTGGACTCATCGAGTGCTGCC ATTGTGCTGTTAGAAATCCAGTTCTGCAAGGGAAGGTTCTGATAGCAGAGTTAGGGGCTG CAGTGACCACTTAGCTATCTGTTTAAGATGAGCTTTGAATCTGGGCTTTCAGTGACATAA TTACTTGAGGTCCTTGACTTGAGTAAAAAAATAAATTCTGATTCTTCTTCTTCTTCTTAA TGTGTACTCTACATGTTTCAACAAATCTCAACCCACTTAATCTTGAAAACACAGCAGCCA CACCATAGCTGATGGCTTTCTTGGATCCTGCAGCCCCCATCCTTTCTTGGATAGGAGACT AACCATACAGCAAGCTGGCAGCTTGCAGGCAGCTTGCAGGATAAGAACCTGGGGACAGAG GGAGCCGCTGAAATAAAAAGAAGGATGTGCTTCAGTTGGACATTTTGCAATTGAATTTCC CTTCCTTCTCCAAGAAAGAAGCTGAATAAAAATGAGCTTGTGTCAAATTTGATCCAAGTA TACTAACTGATTCTCCCTACCCAGGCCTTGGGGGCTTCCCAGACTAATGGTTCCTAATGG TCTTACAAGGCATCAGATGGGCCAGTAATGCTGAAATAGTTAGTGCCACTGAGGATCTAA CCAAGGCGATGGCAAAGAACACCAGGATGCTTGGACCGCAGTATATTGAGCTTGCACCCA GGCAGGGTCACGTGGAATCATCTAAGTGGTGAGCAGCATTTCTGCCCCCTTTATCGTGCA TCCTGTCCGCTAGAGCAGGGCCCCTTCACCTTTTAGCCCTGCATGAGCCCAAACCCCCAA GCGTCCCGACTGGCTGCAGCTGGCACTCACTGTAGGGGTTCTCCTCGTGGGTCCCGCTGA TCCGGCCGTCGGGGAGCACCTGGAGGTGAAAGCCGATGCCCACGTTGCAGTAGAGCCTCC GCTGCCGCTTGATCCCCACCAAATAGCCACTTTCCCAGTTCACCCCGGCAATCTCTCCAG CTAGCCCGGCGCGAGACCTGGACAGCAGGGTGCCCCAGCCCCTCGAGTCCAGCAGCGTGT TGTTGGCACGGGTGCCTGCAGGCGAGGGCACCACCATGCCCACTAGGATGCCTAGGAAGA CGAGAGCCCACAGCGTGCCCTGCAGACGTCCTGCTCCCCGGGACATAGTGATGAACAGTT TCTGTCCCAGGGCCATCCACCTTGCCTCTCAGGCACGTGGTCAGAATTAATGGCCCTAAA bcftools-1.21/test/csq/ENST00000543077/ENST00000543077.fa.fai000066400000000000000000000000221467060157400215350ustar00rootroot0000000000000012 17460 23 60 61 bcftools-1.21/test/csq/ENST00000543077/ENST00000543077.gff000066400000000000000000000021351467060157400211620ustar00rootroot0000000000000012 ensembl_havana gene 1 17460 . - . ID=gene:ENSG00000111241;Name=FGF6;biotype=protein_coding;description=fibroblast growth factor 6 [Source:HGNC Symbol%3BAcc:3684];gene_id=ENSG00000111241;logic_name=ensembl_havana_gene;version=2 12 ensembl_havana transcript 2 16065 . - . ID=transcript:ENST00000543077;Parent=gene:ENSG00000111241;Name=FGF6-002;biotype=protein_coding;havana_transcript=OTTHUMT00000398938;havana_version=1;transcript_id=ENST00000543077;version=1 12 havana three_prime_UTR 2 240 . - . Parent=transcript:ENST00000543077 12 havana exon 2 249 . - . Parent=transcript:ENST00000543077;Name=ENSE00002242290;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002242290;rank=2;version=1 12 havana CDS 241 249 . - 0 ID=CDS:ENSP00000445479;Parent=transcript:ENST00000543077;protein_id=ENSP00000445479 12 havana exon 15979 16065 . - . Parent=transcript:ENST00000543077;Name=ENSE00002260911;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002260911;rank=1;version=1 12 havana CDS 15979 16065 . - 0 ID=CDS:ENSP00000445479;Parent=transcript:ENST00000543077;protein_id=ENSP00000445479 bcftools-1.21/test/csq/ENST00000543077/not-a-start-lost.txt000066400000000000000000000002171467060157400225430ustar00rootroot0000000000000016063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G 16063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G bcftools-1.21/test/csq/ENST00000543077/not-a-start-lost.txt-l000066400000000000000000000002171467060157400227740ustar00rootroot0000000000000016063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G 16063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G bcftools-1.21/test/csq/ENST00000543077/not-a-start-lost.vcf000066400000000000000000000005201467060157400224770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 12 16063 . A G . . EXP=synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G;type=ENST00000543077:4553383-A-G bcftools-1.21/test/csq/ENST00000545279/000077500000000000000000000000001467060157400166605ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000545279/ENST00000545279.fa000066400000000000000000001571041467060157400210310ustar00rootroot00000000000000>5 5:135468514-135524455 TCCCTCTCCCTCCCTCCCTCATCCGGGTCCTGGGCGAGCGGGCGCCGTGCGCGTGTCCCG CGGCCGAGCTGCTAATAAAGTTGCAGCGAGGAGAAGCGCAGCGACGGCGTCGGGAGAGCG CGCCTAGCCGGCTCGCGAGTGAGTGAGGGTCCCCGGCGCGCGCGGGCGAGGGGAACTGGG GGCTGCAGGCTCTGCCCCGGCGGACTCGGGCCGAGGCGGGGGCGTTCGGCCGCGGACGGA GCGGAAACGACCCAGGGCCTGTCGGGCGGGAGGTAGGCCGAGTCCTGGCCTGCCGGGGTC CCGGCTGGCGGACACGGTGCGGCCCAGCGGCTGCGGAGGCCTCGCTGGCTGCCCGGGGCG TCCTGAGGCGGGGCCGGGGCTGGCCCTCGTCCCAGCCCCGCTGTTACCGCCCAGACTTTG GAGGGAGGCGTCTGGGACGCCCTGGAGGGGACCCCCTGACCCCGCGCTGTCCTGGGGAGC GGTTTGCTTTCCTAACTCATCGGATGTACCACCCTGGATACACACCCTTGATAGGACTGC GGTGCTCGGCCGGGCAGCCTGGGCTGCTGCACTGCGAAGCTGTCCAATGGCTTGATGAAT CCGTGCCGCCGTCGCTTTGTGTTTCAAAGATAAGGATCCGCGCTTATCGGTGGGAATTAC ACTCTGGGCAGTTGTGACCGGCTACTGCAATCAGCTGGTAGTTAGACCTGGTTTCTGCCA CTTGCCATGTCAGTTTTCACCACTGCAAGGATTTCTTCTACTTCATGTAAACTTCTCTGT GCTGCAAAGAGAATGCCAAAGCAGCGTCTTTTTGCCTTCACCATATTCAGCCGCTGGCCG GGTCCTATACTTCAATATCAGGGCTCAAATTAATATTCCAGTCTCTTCCCCTCCCCTTTT CCCCTCTCCTCCTTTCAGCTGCTGTTACTACGTGGAGTTTGGAGCCTAAGCTTTGAAAAC TCCCATGTGGCGCGCCCGTCTTAAGTCTGAGCATGCTCAGTAGCCAAAACAGATTTTTGG TTGCAGAACTCGGGCGAGGATACTTGGGGTATTTGGACGTTTGCCGGCTTCCCAACAGAA TGTTCCGGTTCTGGTGGTGATGGCATTGGAGAATGGGGCTTAGGCAAGCCTGTAGGTGAG GAATGGCTGAACACCCTGAGCCAGATGTTTATCTTGATTGTAAAGACAATGTTTCCTGAC CAGCTGGAGCTTTGGGGGGGGGGGGGGGGTGTTGCGGGGGGAGGGAGCAATTTTGGTTGC TTGTGCATTTAAATGGGTGTGGCGCTAAGTATATCTTGTTTACCTTATCTTTCTGTGGAA AAGTTTTGATGTCTAGGTTTGTCACATCATGCCTGTTGCCTAGCACTACCAAAAGGGTTG TTATCTAGCAGCAAAGATTGAATAGGTGGAGGTCGTGGCTTGGCCTCACAGAAGTTGAGA GGAAAGGGTACTTGGGTTGCGTTTTTGAAAATTCGTATTTAAAACTAGAGTACTTGAATT TCCTTAGAGTACCTGAATTGCCCAGAGTGAATTAGTTTTTAATTTTAATTTGAAAGACAA AAGATTGAAAACCTTAGTCCCAGTAGGTTTAGTAACATTCCAAATAGCTTACAATTTCTG CTAGATGCCAATGCAGTAGTATCCATTGTGGGGAAAACAGTACCTACATTCAGTGTGACA GTTTCACATTTATGGATCCAAATATCATTATGAAATTAGTGTTCCAAATTTAAGGAGCTA TTTGCAGATGTATAACAAATTATTTTAGTCTTTTATTCCTTTGGTAACTATTAATATTTT TTTCTCTACAGTGAAAATTGTAAAAATGCAAAACTTAGACAATTTAACAAAACTTAACCT TCATAAAGGTTGTAGATACTATGTTTAGATTTATAAAGTTTAATTTTGATGATTATTTGT GTGATTGTTCCTATACAGCTTCCTTTCCTTCCCTTTCCACATTGTTGCTCCCTCAGTCTT TTTTACATTACTGCTGTTAATTTACCCATGTATCTTTGTTAAAAATACCTTATTCATCAT TTTGTGCTTCCATTCCTTTCAGATCATAGCTGAAATAAGCAAGAAAAGTTAGATTAACCT TCTCAACTGACTTTACTCTCAGGTTTTAAAGGCATCCACATGATATGGTCTAGTTAAAAG GAGGAAGAGAGCAGCAAACTGGAAAAAAAGAATAAAATATTTTCGTAGGTTCTGTACAGA TCTGGTAGTATTATCTGCGTGTCTGGTTCACTGTGGTAGGCGCCACAGAAATGGGTAGAT TGATAATGTGTTGGATTTCTTTCCCCTCTGGCAAAGTCAGCTATTAATTTCAGTGGGAGA CAGTGGCAGAATGTTGTTACTAATGAGGTTTGAATCAGATTGTTGTTTACTGTTGGTTAT GTAACATGTTGCTGGGAGTATTATTAAAAGTTGCATTCTGCAGCAAAGTAGAGGCAAGTA AATTCTGCTTACCCTCTTCACTGGGTTTTAATTCTTGGCTGAACCTGAAGGCACATTAGA TTACAACCATAATTATACCTGGGCAGCCTGTCTGTTTCCTGTTTTCATCATGAACCCAAA CATTATGATTTGCAGTGATGATCTTTTTTGTCCTTTGCATTGAACGGAGGCAGTGTGTTT TCTCCCTCTACTGAAAACAGATTTGTAACTTGGTCAAATTAAAGATTTTAGTGTTTTGAA AACTAGGCAGTAAAATACCAGTTTTTCATTTCTTAATACAGTTACTTAAGTTGAAATACC ATCTAAAAAAATCTATTTCATATATATTCTTTGTCTTTATGTAAATTTTAATATTACTAG TACTTTGTAGAGTTAAAGAAACTCTTTTTGTTTATGACATATCAGTGTTTATTATTACCA GATGTATATGTTGGTCTAGGCAATGAGCCACACATCTGGGTGAATTTCAGAGCTGACTTG AGTACGCTTGAGGATATAGGTGTCTATTCTCTTGGTTTATCAGTCTTCCCTGTTTTTACT TCTAGACGATCTATATTCCTTGTATCTGTCTGTCTGTCTCTCTGTCTCTCTGTACACTAA CCACAAAGAAGGCAAATAGTTTATTTCTTCAAATGTTACAAGCAGCTTATAGCCTATGAT TTGCCCGTCTTCTCATAGGGTCAAAGACATTGAGTAAGATTCCCTTTTATAAGGGATACT AGTAGCCTGAGGAATGATTCTTGTCTCCACCAGTCTGGATATTCTAGAGAAAAGAATACC TGGATATTCTAGAGAAAAGAATATTCTAGAGAAAAGAAAAGGCCCAAGGAAGCTGGGATG CAATATAGGGTGCTTTCCCATCAAAACAGATGATGAAGGACCCTTGGAAGCTGACCCATG GCATCCCCCCGCCACTGGGTTCTAGCTCTGTCGCCCAATCTGGAGTCCAGTGGCGCAATC TTGGCTCACTGCAACCTCCGCCTCCCGGGTTGAAGCAATTCTCCTGCCTCAGCCTCCCAA GTAGCTGGGATTACAGGCACCCACCACCATACCCGGCTAATTTTTGTATTTTTAGTAGAG ACGGTGTTTCACCATGTTCGCCAGGCTGGTCTTGAACTCTTAACATACCTTGTTTTTCCA CTTCTGAAGTTAATAGAATAATAGTCATTGGAATTTGCAGTTCATTGGTGTTGTCACATA CCCTTTACCTCTAATCAGAAGTCTGAATCTGAGAAGTTTGTTTACTAAATGGGAGGTAAA GATTTAGAACTCTTTTGGAAGAATTGTTAAAAACTAGATTGTTGTTAGGACTAATCTCAT AGGCCACCTTAATATTCTAACAGCTTTGTTGTTTTCCAACCTGGAAAGATGGGGTAATTA CAGAGTTCTTAGGTTTTTCATAAATAATCAGCTAGTTCTGGGCTATTTATTTGAGAGTGT CTCTCTCTGTCGCCCAGGCTGGGGTTCAGTGACGCGATCTTGACTCACTGCAATTCTGCC TCCCGGCTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCC ACCACCACGTCCAGCTCATTTTTTGAATTTTTAATAGAGATGGAGTTTCACCTCGTTGGC CAGGCTGGTCTCGAACTTCTGACCTCAAGTGATCTGCCCGCTATGGCCTCCCAAAGTGCT GGGATTACAGGTGTGAGCCACCGTGCCTGGCTGGGCTCTTTATTTAGTTTTGATTTTTTT TTTTTTTTTTTTTGCCTTGGGCAGCTAGGGGGGATGTTTTTGGCCCAGTTCTAGTAGAGT GGTGTTTTCAGTGACTTTTCTTCCTCCTTTTACTGTATCCTACCTTGGTTGAGATGATAT TTTGCAAGAAAGAGTTCTTTATTAAGTCAGTTCTGTGTGTGCAATACTATAATTGTAATT CACTTTTGGAAGCTAGTTATTAACATAACATTTTGTAACTAGGTTTTGCTCTTGAATTTT TTGGGACCCCCCCCCGCATCTCTTCCTATAGCATATATGTACTTTATAGACTGGTACAAT ATAGAAGTTTGAAAGTGATTTGACCTGTTAAGATTTTAGCAGGATTTTTTCTTTTGATAT CCATATATGTTGTTTTGTTATACCGAAAATAATAGAAAAAAACTAGTGTCCCATTCCCAC TTTTTCTCTGAGCATAGCAACTGGAGTCTTGGGAGGAGGCTTACATCTTTCAAATTTAAC TATGATCTCAGAATATGGCTGGTGCTTTCAAGGCAAGTTTTGTTTTGTTCAGGTTTGTTT TCATGATGTGTTAGGATCTGCCTAGTATCCTATCTGGTAGGCTGTACAACTTGAGTTCTA GTTATTCTGGTTTGTGTGTTCCCAGGAAGAGGGGGGTTCTGCAAAAATATTTAAAAGCCA GTCTTCTTCTGTTTTCTTCTTAGTCACATCTTCTGTCTACTTTACTCATTGACCATTTCT CATTCTTTGGAGATGAAAGTGTAAATTAAGTGAATGATGACACTAGAGCTGAAAAGTTAC CCAGAGTCATGTTTATTCCCTTTTCTACTAAGCAGGGAACTTGAACTCTGGGTGCACATG AGTTCTCTGGAGAACATCTTCATAATGCACTGTAATATATGTCGTGTACACAGGTTAGCT CTTTGTGCTCCAGAGACACATTTTACAGTCATGATTTGGTATCTGCACTTGATGATTTTA TAATTTAAAGGAATCACTACAAAGATTGACCAGCTCTGTGTCTGTTCCTGTGCCTACACG CCTGTACAAGCATACTCAAACACATCTGGTAGCAATGTAGGAAATCTTGCAGGCTCTGTG GGGGTGAGTGATACATTTAGATCAGGCTCTGTTTAATTAGGGGACTTAGAGGAGCAGGTG AAGCTTAAAGAGTGATTAAAAACTGGGAAACAAAAGTCTGGCTGTGGGAGATAATAAAGT AGAGAATTCTGTGGGCACAGAATAGGCAAGAAGATTATGCAGTGAGAAGTGTTGGGAATC ATGAGTTCAGCTCCTGAAGGGCTTTGAAATCTGCTATGAGAACTTCTTATGTCTTTGGAA ATCGGGAGCCACAGTTGAGGAAAGTGGTGATTTAAATGTTTCTCTGTGAAAATAATTTTG GCGCCCATGTAATTGTATCCTGTCTTTCTTGTAGATGTTCTTATAAAGAATAGGATTTCT GAATCTAGAAGAGCTGTGAGCAAACATGCTTTTGGTTTCCTTCTCCTCTCTGCGTGCAGT TGTGAATGTGGCTTACAAAGTTGATAGCAGTTGTATACATGGATCTAGGGATGGTTTGAC AGTGGTGGTGGTGGTTGTCTACTTGCTGACACTTGGTGACTACTATTGATAATGAGAACC ACAAGGGTAAGAGATTTTTAAAGCTTTACCCCCACATCCCCCCTGCCCCCAAAAGTTACC CTTAGGTTGTATGTATGCAAGTGTCTTTCTTCCATTGCAGGAGATCCTGAGCACCTTGGT TCCCAAGCCTCCTGCATGGTCCGAGATTCTTGTTAAAAATGTGGGCAGTAAGGCCCTTCT GCCAAGCTTAGTGAATCTGAATTTTGAGGGATGGTTCTAAGGAATTTGTTGATTTAAAAA CCCCATGTCCAATTATTTTGTACAGGTTTGAATTAGAATACAATGGGTTGTGACCCATTA TGGGCATTTATTTTCATGGGATGATGTGCTCAGGAGATTTTGTTTTGGCCAATAGTGTTG AGGAAAATGTGGGGATTGGTTTGCTTGCCTTTTTATTTCAGATTGCAGCAGTCATAGAGA TGTTGGAGCACAAAGTGAAAGAGTTGTTTCTGTGAATTCACTTTAGAAATCTAGCTGTGA GCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTTTCTGTATGTTTTTCTGTATGTA TGTGTGTCTCGGGGTGGGTATTGAAGTCAGTTTGTGTGTGTGTTTATTATGAAAGTTGGT CAGGATGTAGTACTTCCATAACCTTAGGTAAGAACAGGACCTTTGGGTTATTGATTCAAC ATGAATTCATTTGAAATAGAAGCTTTGTGAAGCTTAGCAACATTTTATTCATATGGTTAA TGTGTATAAAACTTAACCCTGAATCTTCCTTTAGCTTTCTTATCTGCATTTGCCAAATCA GTTGATGTCAAACCCCATTCTTCCAGTTGTCCAGGCTGATACCTTGGAATCATTGTTAAC TCCTTTGTTCTCATACACCCCATGATCTCCTTCATCAGGAAGCTTACTGTCTTTCATATG TCTGCTGCTCACCACCCCACTGCTATCACCCTGGTTGTAAGCCATCGTCATCTTCTCCCC TCCCTTAGATTACTGCATCTCTGAACTGGTCTCGCTGCTTTTATCATTGCTGTCCACCCC TCCTCCTGCTTATTCTCAACATACCAGCCAGGATTTATTTATTTATTTTGAGACGGAGTC TTGTGCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCTACCTTGACC TCTTGGGCTCAAGTGATCCTCCCACCTCAGCCTCCTAAGTAGATGGGATCACAGGCATGT GCCACTGCACCTGGCTAATTTTTTAATTAAAAACAATTTTTTTTTGTAGAGATGGAGTTT TAAAAACTATGTTGCCCAGGCTAGGCTTGAACCGCTGAGCTCAAGTGATTCTCCTGCCTT GGCCTTCCAAAGTACTGGGATTACAGGCATGAGCCACCACGCCTGGCCCAGGATAACTCT TTTTTTTTTTTTTTTTGAGATGAAGTCTAGCTTTGTTGGCCAGGCTAGAGTGCAGTGGTA TGATCTTGGCTCACTGCAACCTCTGCCTCCCGGGCTCAAGCAATTCTCCTTCCTCAGCCT CCCAAGTAGCTGGAATTACAGGCACATGCCACCACACCCAGCTAATTTTTGTATTTTTCG TAGAGACGGGGTTTCACCATGTTCGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTAATT TGCCCACCTCGGCCCAGGATAATTCTTTAATAGTGTAAGTCGAGAACTATCATGTCTGTG CTCAGAGCTCTCCACTGAGTTCACAGTTTCCTTAGAGTACTGTAAAAGCTAAAGCCTTTA TATCCAGCATGGCCATTCTGGCTCTCTGGTATCTCTTTGACCCCACTCCTTACCTTTTCC CCCTCGTACACTGTGTTCTCAGGCTATACTGGTCTTCTAGCCAGTATATGCTCTTCATGC CAGAAGCATGCCAGACATGCTCCTACCTTAGGATCTTTGCATTGCCTGTTGCCTTTACCT GTAATGGTTTTCCCCTAGATATATGCCTGTTGGCTCACTCTTTTATTTCCTTAACATTTT AACTCAGTTGGCACCTTCTTGGTGAGACCCAGCCCAGCCACCCTGTTTAAAATTACACCT CTCTTCCAGGACTTCTTGTCCACCTTCCCCTGTTTTAATTTTTCTCTATAGCACTTTTCA CCTAACAAACATATCATTTACTATATCTCGTTGGCCTCCTTCTGCTGGAATATAAGCTAA ATGAAGACAAGTGTTTTGGTTCCTTTTATTCACTTCTATATTCCCAGCTCCTAAAATGCT ATCTTAATAAATATTCTTTTGGATGAATGACTTGAATGAATTTGACAAGTTATTGTAATG TATGTGGTACTGTTTTTTAAAGATTATATTCTAGTGCGAGAGACAGAAATAAAGTAAATG AACAAATTATTATGAATCAGTTAATACAGTGAAGAAAATGAACATAGTATTGGATTAGAG ATTAGGGAAACTCTATATAGGATTATGGGGTGATCAGGGAAGGTATCTGGGATGAGAGCT AAAGCTGAGACTTAAATAACGATAGAGCTAAAAATTAGTGGCCAGGGATTAAGAAAAGTG GTATAAGCAGAAAATGGCATTTGTAATATCTGAGGTTCAAAAGACATTCCAGTATAGGAA GATAAATGCTTTTGAAGAATGAGTTCTTACTAATATTTATTGGGAGCAGGAATAATGCTT CTGGAGTTTGATTTCATTGTTTTGAGGAGCAACAGCTCATTTGTAGTAACAGGACACACT GTGAAAAGTGCTAGATACCTGGATTACATGCCCTTTCTCTGTCTCTCTGTGTTCCTCTAG TAACTTGAGTTTATCTCATTGTACTTACATATAGGGGTATAGTTTGGTGTCTGTCGTGCT ACGTTATTCTGTGAAGGGAGATTCTGTCCCGTTTGCATTTTTGCTATTCCCACTCTTCAC TCATATAGTACCTTTGTATGGGACTTAGAAAAAGGCCTTCTCATTTATTCCTTCACCCTT GGCTAGTGCTGATAAACCCCTGCATGTCCTACAATGTCTGCTAGTTAGTAGGTGCTCAAT AAGTGTTTAATGATTCATGGCTGTTATAGCTGCTGAGTCAGTTAATGCACATATACTTAA AGAAGTAGGTGTACCTTATGATAATCATTTCTGTATTTCTGTTGATTAACCTAGAGTACT ATAGTTATGGAAGTATTTGTACCTAGTTTCTGATTTGATTTTTCTTAGTTTCAACCTCCA AATTTGTATAACCCCAAGTATATTAGAGAGAATTGTTTTGAAGCAGGAATGACTCATGAT AATGTAAATCCTCTCTTTAGTAAGGGTTCATAATATGGCTGAGGTATAGCTGCACTTTAA TTTTGAAACCTGTTTTTCCTCTGACTCTTCAAGAAATATGTTTATTTTAAAAAATATAGA ATTAGATGAAGCAGAAAGTGAAAAGTACACCTAACCCCACCACCAGAGCTAATATCACAA ACCCTTTCTTTCATTAAACAAATATTTATTGAGCATATGTATCACTAGGCTTACAGTGAT GAGTGAAAACAGATACAGCTCTTCTCGTGGAATTTACATTCTTGTGGGGACAGATTTGAA AGGTAAATGTAAAAACATAGGTGTGGTAAGTGCTACAAAGTAGGAGTATGTGATGCGGTA AGCATATAAGAGGGGGACTTCTAGCCAGGACGGTTTGGGAAGACTTCCCCGAAGAAGGGA TGCTTGAGCTGAAAGAGAGGTGAGGTGTGTGTGTGTTTTGTAATGTGATAGATTCATTTG TAATTCATGATATACCGTAATTTTATAAGGTTTTCATTTATGGCTGAGGTACCACTGCAT CTCTTTTGGTACACTAATGACGTTCTGTGTTCAGTCAGTGGTTGCAGTTTTTCAGAAGAA TCAGGGAACCTCACGTACACAGGAATTTCTAAATATTATGATTACCTTGGTTTTCTTTCT AGCTTTGAGGTCATTTCTCTAAGAAATGACAAAATACATCAATAAAAGGGTATTATCAAG TCAAGTCTTCATAAACCAAAGGTATACTATGAAAGGCCAAGATAATAGCAGATAATGGGT TCATAGCTGTTAAGTCCCTCCAGTTTCTAGTGTAAGAAGGAGCATACCTTCCTGTCTGTT CAATTATTGGCTCTCTGTGCTTGGTGTACATTTTTTTAAACTCAATTTTAATGCCCTATT TCTGTTGGCTATCATATGGAAATAAATATAGGATAAAACTAAGTGATAGGCTAAATGGCA TATGAAACTCTTTATAGCCCCTGTTCTTTTTTCCATTACTCTCTAAGATCTTACAGAGAT TATGGTTAGTGTCTTTTAAGCCTGAGTTCCTAGCATGGAGTATTCCTGACATACACTAGT GGGCACCCGGTAAATTTTGAATAAATCAAATGTCTCCTCTGTCTAATATCACAATTCATC TCTCCAATTCATATGATCCTCAATATCTACATATTTATTCCTTTTCTCCTTGAGCTTTAA TTTTATATCTTCCTGGATGCATGCCAGTATTTGTTTCCTTATGTCCCTCCACTGTCACCT TCTTGCCTTGTTTTGGCCATAACTAGAGTTACCCTTTGGTAAGTGATGTTTTCATTATTC AGGGTTTAAACCTTAACTTTTCTAGTTAGGCTTCTGTTTATTTGTGACATCCCTCGTATC TCTTTTTTTTTTTTTTATTTAATCACGGTGTGTGTGTGTTCCTCTCAGTTAGGTTACTAC CATGGTTTTCATCTACGCTTTGTCCCCCTAGTTAGTCTCTTACTTGGTCCTTTGTTGTTG GAATTTTTGTCTTCTTGAAATACCTCTTCGAACATGTCTTTCGGCTTAGATAGAACTCTA CACGGCACATAGAACTACTTCTAGCAGTCTGACTCCTTAGCCTTGTATTCACAGTCTTTC CCTGTTTGACCTTCATTCTGTGGTTGTGCCTTTCCCTTTTGCTTCACAGTCAGACTAGCT GATTGTCACCTCCTAGCCTCCCTTCCTCATTTGGCTGAGTGATTTGGTTTTCCTCGTCCT TGTACTTTCTTGCCAAGTGGACTGTGAATGATAGATTGTTATATTTCTATCTCGTATTCA GTATTTTGGTAGTCACTCTCAAAATTTGTGCTTATATGACAAGCAGTTATTCTTGCCTCA TCCTTAAGCTCCTATTCACTTAGGTGCAGTGTGTTTGAGTTTGCAGGGGAGGGGTAGAAT CTGTCCAAACCAGCTGTTTTTTTTGCACAGTTGCTAAACCCCCTCAACCAACTTCTTGTC TGTTACTGGCCATTTGCAACACAGTTAATTCCTTCTTAATCAGTCATATTCACCAGTATA TAATCTTTTCACTTTTTTCTTCTTCCACTTTCCAGTTATACTGTTCTTTCTGTTCCATGT ATGTACTCTAAATACCTCATAAACCAGAGGTATACTATGAAAGGCCAAGATAATAGCAGA TAATGGGTTCATTATCTGAGTCTGAAAGTGTTTGATCACTCAGATTTAATTCCATTCATT CATACGGCAGTTTTGATGAAAATTGACTGTCTCACCTAACACGAATTGTCCCGTGGGTTT CCTAATGAGATTTTAGATTTAGATTTTGGGGGATTCTCTGGTTTTCAAGCTAGAAGTAGA AATTCCCTGAAAGGTTTCATGGACACTGTTCAGTGTAGTTTGTGTTTTTCTTTTATGATG CTCATGGTTAGCCTGTTCTGAATTACTGTAACAAGACTTGGCTTTTAAAGAAAAGGCTGT TTGACACTTAGCCTTCTGAAAGTTTGGTTTAATACGGCCCTAGTAAGAGCAAAAAAGAGA AGGCAGAATTTGTCTTCTATCCCTGATTATGTTATTGAAATAAGATTAACATTTATAAAC AACTGTTTTACAATAGGTTTCTATGGAGGTTTATTGCAAAAGAAAATAGCTTGACGATTT AAGTTCCTTGAAGCCTATTGACTTTTTGGTTTTCTTAGGAACTAAATATATTACCTCTTA ATATGTTTAGATATATATAAATATATCTTATTATATTGGTATATATTAATATATATTATT CCCACTGGTGTACTTTAGGATAGGTATGTTAGGTGGCTCAGGATGAGGATTACAGAGGTG CAAATAGAATCTGCTCAGAAGCCAGATTGTCTAGGGCATTATTTCACCTATGTGGACTGT CAAATGCATCTTCCCTTGACTTACTAGAGAACTCAGAAGTAAGCAAGCCCTGGAGCACCT GAAAGTACCAAGGATACAAATCATGTATTCCATGCTAATTGGGTTCTTTTTGAGACAGAA GGAAAGTTCATTTTCATTAGGTAGTTTATCAAGTTTCTCCAAAAGCAACACTGAGGAATA TAGGAGAAGCTATGAGAAATGCAGAAAGAGAAAAGAAAAAAAAAAGAGTTAAAAGAATGA GAACAAAGGAGGGGTTAGAATGACAGATACTGGGGGCAAGTGATGGGGAGCATCAGAAAG GACTTTGAGAGAGGACAAAAGAAAAAGCTGCCGTATTTCTTCTAAGATGTAATTTTTTTT TTCACCTCATAACATAACATTAACTGTCTTACAGTTAATAGCATCTGAGTATTGCTTTTG GCCAGGTGGCAGTTTTGATCTAGTTGTCATTGTACAGGCATGGCTCTGACTTGCTGTTTC TGTTGCTGTCATTTCAGTCTCAGTGTGGACATTGTTTTAACTTCTCGTGTTGAGTAATTG CCATTTAAAATATTTTCTTAGTTGTTGTTTTCACATCTTCATTTAGATCCTCTAGGGACA CCAAACAGGCACCAGTATCAAAATTTGCAGGATGGTTGTCAGTGGCTTGAAAGACAGTCC TGGAGCAGTGTCGGAACATTCTTCATACTTACATTCTTGATGGCAGAAGGATGATACTGT GAATAAAAATTTTAAGTTATAAGAAAGCATTATGCCATTTACTTTGCAGCTTTTTCTTCC TTCAGGGTTCATAAAATAATGCGGACTCTTAAAGTACATGACTGTATGCTTATTGAAATA AAGGATCCCAACCATTTATTTAAAATCCTCAGCCTGATAGCAACAATGTTCATGATTATT ACAACAATAATAACTACAGTTGCCCTTTATTGAGTATGCACTGTGTACTAAGTGTTTCTC ACTTAATTCTCAGAACCTTTTAGGGCCATAGTATTCACGATACAAAATAGGAAAAAATGG AGATTTTGGGTGTAAGTGTTAGATCCAGAATTTGAACCCAAGTTTATTAGGCTTCAAATC CGGTGCTGTAGTTCCTCATCCTGTTATATAAAGTATTACTTTGTGAAAGACATAGAAGCT TTTATGCTTAAGATAAAATTGTCTCCCTTCATCCTTCTCCCCAAAGGGTCATATCCTGAC TTCTTTTAGCGACCTTTATATCTTTAGGGCAACTCCATTCTCCACTGTGTATCGTAGATA GTTATGGGCACATTTCAGTTGTTCTATTAATTTGTGACTATTTAGAGTTAGTCTGGATCT GATTTATATTTCAACTCTTTATTATCTAGCTTAGTGCCTTGCCTTTTATAGGCACTCAGT AAATATGTGTTGTATAAATAAGGCTATAAGTGTGAGCTTAAGTTTAGCACTGGTTATTAT GTATATTTGTGTCTCAGTAGACTCTGAAAGCATTTAGAAAAGGAGTATAGAGGACCAAAA TTTAGCTGTCCAGTAATCTGTAATGTGTAAAGACTGTTGCAGTTGCTAAGTACAGTCTTT TGGGATTTTCTCTATTACTGGAATAAGTGTAGAGGTGATGTAGAAGAGTATTATGGGGTG TTAGATACACAGCTGATTTAAATTGAAGATAGGTGTTCTCAGTGTTTCTAAATTCGTTTT ATTTAGTGAAAGGCAAAGGGGGCATGAAAAATTGAATCAACTTTTCAGGAAAGAGACTCA AAATGTTCAGAGGTATTGCAGGTTCACTTGTGGCTCATGCAAATCAGAACGTATTTTATT TTTTGTATACATAATGAGAAATTTTTTCATAACCGAGTACTTATGTGAGGATACTAAAGT AAATCTATTGCTGTAACCCAAGCTCTCTGATCATTTTATTTCAAATTTTGGACCAAGGTG TTATTTTGAATATAGTATAGTCTGCAGAAAAGACTAGGACAAAATGCATCCATTATATGG GTACCATAAAGAAGTTTTAATCTCAGTTTAACAATTTTACTTTTACTATAGGTGGTTTAG TTCCTTTAGAAACCTAGCTGTTAAATATTAAGAGAATAGATGAGTAAAATATGATTGCAC CATTAAAGGCATTTAAAAAAATCTATATATTCGGGTGAGGGAAGAGCAAATGCTTGTGGT GTTAAATAGAAAATGCAGAATACCAAGTAATATCATGTTATATCCTGTTACGGGCAGTTG TGGGCAAGACTATATATATGCAGAGGAAACAAATATAAGCATACCATATGTTAATGGTAT GATTATAGGTGAGTATACTTAGGAAAAATATTTTTTAAGGAAAAATATTTTTTAAAAAGT GGTACATTGTCTCATCATTTCTGAGATCATTGTGTTCCAGTAATAAGTGTGCTAAAAATG TCCTAATGATAATTAGAAAAGCTTTGGAGTAAGATCACCACAAAAAAAATATATTTTTAT GCAGTGGTAGTAAGCATAAAGCTAAACCTTTCATTCCTGCTGATTGACCTAGCACAAATG TGAGAAGGTTGGGTTAAAGTTGATAGGTTGATGACATACGTTAAGTGGTATAAAAATAAG TTTGAAAATGAGCAAATTAAGCTGGATTATTCTTGATCTCTTAAACTATACAATCTTATG ATAATATTTAACAATTTGAATGTTTTGGAGAAGTCAGGAATATGAAGAACAATTACAGAC CTGTAAGGGAAGAAAATTCCTTGGCAGGAGGGTTTCTTTCTAGGAGGCAGTCTGTACAGT GGTTTGGAATATGGATTCTGCAGCTGGACTGCCAGGGTTCAATTCTCAGCTCTGTTTCTT GCTTTCTGTATAATTAAGCAAGTTACATTTAATTTCCCTTTGCCTGTTTTCTCATCTGTA AAATGAGAATAATGGAATTTGCTTTATAAGGCTGTTTTGAAATTTAATGATTTTTGGTTT CTAAATGTAAAGTCCTTAACAGTACTTGGCATAGTGAGTGCTCAATAAATGTTAGTGGTT TATTATTATTACCATTATCAAAGGAGTATTATGATTCCTTTGCTTAAGCAATTGATTTTT TTTTTAGAAAGGAAGCTGTTGAAGTTATTGAAGTACCTGTTGCTATATTCTAAGAAATTA AAATGTCCAGAAATCTGCCTCTGTAAGTAACCTTTTAAGATCATTCATGCCACTCTGTTT CTTTAGTCAGTAATAATGCAGCCCATGTTCTATGCCTTCTATAGAGAATTTCATTTAAAA TGAAACCACTGAAAAATGTAGACCACCATTTTATACTAAATGGTGAGTAAAAGGTCTGAT TTTATCTTGAAGAATGAAACTAAAATTCTGGGAAAACATTAGCTTATAGTAACTGTAAAC ATGCATGAATTGTTATAATGAACAAATAATGGATCAAGTGTGAATGGATAAACAATTTTT CCCACAAAATAATTCAGTATCATTATATGACAGCCTTCAATTTGACATTTGTGGCATTAG CTTTAAGTTGTTCTTTTTTTTGCAAAAATATTGATAAAAATATATATACATTTTTTCAAG GACCTCTGTTAAATTCTTTGATAGTCAAGTTACTCTTACCCTCCTCCCGAACAAAGAATG TCTTGCTTACTGATTACTGTAAAAGTGGTAGATTCCCTGAGCTCAGTATTCCTCATCCAT GCATCAAGACTACAAAAAAGCACAAACTCATACATATAAAACATGGAGAATCTTATAATA CTGAAGGAAAGATTACGTGTTATTCCTTCTATACAACATTCACAAAAAGGCAAAACTATA AAATACATCACATTATCCCCATGGGTCTTGGGGACAAACAAAACCTCAAATAATGTCAAT GCTTATGCTGCTTGCTGTGCCCAGAGTAGCAGAGTCTCTAACCCAGGAGTCTTATGTCCT TTGGCACCATCCAGAAGACAGTAACAGACTAACTTGTAAGTGGGGTAAAATCAAATCCTA GATCCTACATTGTTTGCCATCATTTTTATAAACTTTGGAAATCTTGGAATTTTTGCAAAA TCTGTAGTCTCACTCATGGTTCATAAGCCATTATGGTGAGGGAGACACTTGTGAATAGGG ACTGATTTTATAAGTGATCAGTCACAAGTATGTTTTAAAGATATTTTTAAAAATTGAAAT AATCATCTAGTAAAGCACACAGAATTAAAGTGTGTAGCTTAATGAACTTCTGCATATGGT ATACATCCATGTCATCATCACCCAGATCAAAATATGGAAAATTTCTAGCTCCCTAGAAGG CTGTCTCATGACCCTTCTTAGTGCTCTTCTGGCCTTGATGGCATAGGTTAGTTTTGCCTG TTTTTGAATGTTGTGTAGATGGAATAATGTGTAATCTTTCCCTCAGAATATATGAGAATT CTCCATGTTTTACACATACTAGTTCTTTCTGTAGCTGTGAAGTATTCCATTTTATGAATT TATTACCAGTATTTACCCACTCTACTGCTGATGAATATTTGGGTTCCAGTTTGGGACTAT TATAAATAAAGTTGTTAGGAACATGTACTTGTTTTTTGGTGGACACAGCACTCATTTCTG TTGGATATATACCTAGGAATGGAATTTCTGGGTCATAGGGATCTATGTTTAGCGTTAGTG GATACTGTTAAACAATTTTCAAAAGTGACTGGACTAATGTATATTCCTACTATCAATATA TGAGAGTTCCAGTTCTGTATTATCATGAACAGTTAATCTTTTTTTTTTTTTTAAGTGTAG CCATTCTGGTAGGTACCGAGTGAGATTTTACTGTGGTAGTTTTTGTTTTCTTTTTGCATT CATGTGATAACTAATGATATTGAGCCCATTTTCTCATCCAGTGGCTATTTTAATGTCCTC TTTTGTGAAGGATCTGTTCAGATCTTTTGACTATTCACTAATTTTTATGATGAATTTTTC TCCTTTTGTAATGTAAGTTGAGACGTGGATAACAAGTACTCGGGTAGCTTGCACATACCA CTTTACCAGTTTGGGAAGTATAGAAAACATTTTTAGAAATAATTTCATCAAAAGTGCTAA GTTTTTTAGTCATTCCATATTTAAAGAGTTGAGTGTGAGATTTGCTCCTCTCCCTGTGCT AGTTTTACTAGTAAGAGTTCTAGGTTTTTAAAACTGACACCTATTGTTCTTTTTGAAACC AATCTCTTGAAGTTTAGTGGCATACCCATTCACCAAAGTCACTGGCCTTTTCTTTGTTTA CATTCTCTTTAAACTCTCCCATATGTTTAATCTTCTGCAGTACCATTGTATCTAGTTCTG TCTTTTTAATAGTGCATTATCAGTAACTCACTATCAGGAAACTCTTTCCTAACAGTGAAT GTTTCGTAATATTTAGGTGTTTACTTACTGTTCTTTTCACTCTGTTGCAAACTTTTTTTT TTTAGCTCTTTGTGCAAAATCTTAAATCTGTTTCTCATCTTTACCTGGCTAAACCTGTAT CTCCAGTCATGACCTTTTCCCAGTGGAGTTTACCACCATTTCTACTGACAAAGCTGCCTT CTGAATGTTTTTAATTCTGTGGGTAGAATTCTCATTTTATCATTATCTTAGTCAACGTGG GTTTAAAATTTGAAATTATCTCTTAATTTCAAGGTACAGTTAGTAGAAAAATCAGTGACC ATTCATTAAGTATCATAGTGTGTGGTATGGCACATGCAATGGTCCAGGTGCTGAAGACTA CTTCTTAGAAGGATTTTGTACTGTATTTGGGAAGTTATGATATTATTTATGACTTATTAA TTAGTTTTTATTATAAATATTCAGTGACCATAGCCTCTTCAGCATTGGGTGGTAAAGGAA GTCTTCACAAAAGGGGATAGATTGGAGCTCATCATTAAGAATGACTAAGATTTCTCTTGG AAGACACAGATGGGCAGAGGGGCAGGGATTTGGATTGGATCAGAAGGTGTGTATAGTGGA AGAGTAATGGGCAAGATTAGATTAGGACTAGATCTAGCCAGTCTCTTAAGTCTTGGTTCG TCTTCTTTCTGAATGCTAATGATTAGAATTCATGTTTGAATAGTACTGTTGAGTTTGTAA AGCTTGTGTTAGATAGACATTAGTACTTTAATATTTCTGTGACTTAGGAACCATCATCTC TATTTTACAGAAAAGTTAATAGGCTTTGAAAAAGTGATACTAGTAAAGAACAGAATCTGG TGGGCACAGTGGCTCAAGCCTATAATGCCATCAACTTGGGAGACTGAGTCTGGTGTGTTT CATTTCCAGGCATATTTTTATTCTCTGATATCATAGATATCTATAAATAACAATTTTTTT GTTTTAAGTTTGATATAGACATCCTTAGAAAGGTATATATATTTTTACAAATTGTTTTTC TTACTCATTTATTTGATAAATGGACACTATTCTAGGTCCAGGGCATCCAGTGGTTTTGAG GGCAGACGAGACTACCTGCATACTAACATTGCATTGGGGAAAACAAAGTAAATAAACAAA GTTGATAATGTAATATCAGATTAGGGTAAATGCTATAAAAAATGAACAGGGTCAGGGGAT AGAGAATGTTGTGAGAATGGGCTGTCATGCTATTTTCAATCAAGTGGTCAGGGAATTCCT CTTTCAGGAGGTGACCTTTGAACAACTGAATTAATTTGAGTGAGTATGCTGCGTTAAGTT ACGGGAGAAGAGAATTTAGGGGAGAGAACATCAGATGCAAAGACCTCACATAGAAATAAC CTTAGAATACTTGAGAAATGGAAAGAAGTTAAGTGTGGTTAAATGCAATTAGGTAGGATA ATGGTTAAGAAATGAGTAAGGAGAAGCCAAGGGCCTGATCATGTATGATATTGTATTCAG AATTCTGGTCTTGAAGCTCCTGTCTTTTTGCCTCCCTCTTCCTTAACTGTCTCTCTGTTG CTCATACACATACTCTCTCACACATACGTACACTACCCTATCTAGCCCCCCATTATATTC TAGTGTTCATGAATCAGTCAGCCAGGCCTGTCTCTTATCTAGCCTAGGAAATGCTATGTT CATGTCTGCCTATATATATATTTTTTTGTTTGTGTGCCTTTGCCTTTGACATTTCCCATC TCATCTCAGACAACCAAACCATGGTTTTACTTCCTGACCCACATGGATTTTATCATACAT CCTTGATGTAGATGCAACTGAGGTCAGCCCTTCTTACAGTTCATTTAGTACATAACACTT TATACTCTGTGACCTGTTAGTGACAATTATGCTTTCATTCTCTTTGTTATATCTCTCTAT TTTAATGTGGCCAGTTTTGTTTGCCTAGGAAAAATCATCCTACATAGGGCTGGGCAAGAC AAGGCACAAGGCATATCCATACATAAGGAGGATATCTTTACTTCCCTGTACCCTTCCCCA CCATGGTTCCAGCATAGAAGGCTGGATAGCTGCCAGTAGTTGATCGGCATCCAGAACTGT ATCTGGTACTTTAGTAGGCTCTCAGTAAGTGTATTTTGAATGAATCAGTTTATTGACTGT TGAGATTAAACCCTACTTGGCATAACTTTTTTTAAAAAGCCCCATCATGGCTATTCACAA TACATGGGATGTAACAAAGAATCAATAATTATTTGTTGAGTGTATGTCAGTTTTACTTTA CTCTGTGTTTACATTATCTTTATTTACTTTATGTTATTGTCTGGGCTTTAGCTGAGCACA TACATTCTTTTCTGGAAAGATGCACCCCAGTCCAGAATAATATTGATGCTAGAATTTTTC AAAGACAAAGCTATAGCTTTTGGCAATTGTAGGCACAAGAAAGGAAGCATCTTTTGTTAC ACCATTTTTCCAAACGTTATTCTTGTTACTTTAGTAGGTATTTATCGTCTGTGGTTGGCT GTGCAGCGATCTGCAGGAGATCTTACACATTCTTTTTATTCTTTATTTAGAAATGGGATC TCACTATGTTGCTCAGACTGGACGTGATTGAACTCCTGGGCTCAAGTGAGTCTCCCGAAT AACTGGGATTACAGGTGTGTGCCACTGAGCCTGGTTTTTACCAGCTTCTATCGGTGGAGT GCCTGTCACTTCCACCTGTCATCATCAGGAGCTTCTTAATGGTGCAGAACAGTGGTTTAC CTGGAGCAAGCTCATTAACCAATATAAAATATCACTTAAAATAAGCCGATAGGAATTATA AAATTAGAAACTGACCCTTTTAAAATGAATTTATTCTCTTTAAATTTATTCAACATACTT AGTTTTACAAATAGATACTTGCCATTTTACTGGCAGTTATAATGATTTATTTGAGGGTTT GGTACATCTTATACAACCGTGAATACAATTTGCATCTAATAATGTGACTTCAGTAGTATC ATGATTTTTGTCCAAACCTTCTCAGTCTGGGAAACATTTAAAGAGAATAATGACCTTAGA GAAGAGCTGGATTTCTTTTAAGACTTCTATTCAGATCAGGACACAATCACGTTCAAAATT GACATAGCATGTAACATGGATTTCAGTGAAGAAAAGTACTTCAGAATCAAATTTTAGAAG AGTGTTTTAGGGTTTAGTGGCCTAATCAAAGGGAGTCCAGAAGCTATTTTTGGATAATAC ATAGGAGGTAGAGCAACCTGGTTTTGCCTCTGGTTATCATTTGACATTGCCAGTGTCTTA CTTGTTCATATTATGGGGAAGGAATCGAGTGGTCACAGAACTTTTGGAGAAAATTTATCA ATTTTTTGTTTACTTTGTAATGCTTTTCTGTTCTTATTTAATAAAATATGCCTTTCGATT ATATTAATTTAAATTTGTATATATTGAATTGATTTAAACTAGGATCCTTTCCCCCTTTCT CTTTCAGGACTTGACCCAATGAAAGAAGCATATGGCACTTGTGAAGATAAATGTTACTCC TCCCTTTTTAATTGGAACTTCTGCTTAGGACCTGTGTATGACGTTTCACCTGTGATCTGT TCTTTCGGTAGCCACTGACTTTGAGTTACAGGAAGGTCTCCGAAGATTTGTGTCAAATGA CGTCAATGGCCAGCTTGTTTTCTTTTACTAGTCCAGCAGTAAAGCGATTGTTGGGCTGGA AACAAGGTGATGAGGAGGAGAAATGGGCAGAAAAGGCAGTTGATGCTTTGGTGAAGAAAC TAAAAAAGAAAAAGGGTGCCATGGAGGAACTGGAGAAAGCCTTGAGCAGTCCAGGACAGC CGAGTAAATGTGTCACTATTCCCAGATCTTTAGATGGACGCCTGCAGGTTTCTCACAGAA AAGGCTTACCCCATGTTATATATTGTCGTGTTTGGCGCTGGCCGGATTTGCAGAGTCATC ATGAGCTAAAGCCGTTGGATATTTGTGAATTTCCTTTTGGATCTAAGCAAAAAGAAGTTT GTATCAACCCATACCACTATAAGAGAGTGGAGAGTCCAGGTAGGTCTTATTCCTGAGAAG AATTTGGAAAAACAAAAACAAAAAACCTCTCTTCCTGATATGCATGTAACTAGATTTAGT AATGAAAAGGTTGTATTAGCTTTGTGTTTCCATCTTAAATATTCTAATCTTGGAAGGGCT ATTGGATTTTGAGTTTAGCTTTTTATATGTAGGTGATACAATTCTCAGGTGGCTTACTCT AATTCATTATTCACTGTAAGCACCCATATATCTACTCTGCCTTTTCCTGTGGATGACCTG TCTCTGTTTTATTTAAAGCCTAAGCTCCAAGTGTGTACTATATCCCATTCCTTTTTGTCA AATGAAGAACTTTGTTCCTACAGTTATCATCCTTCTCTCCAGCATTATATTTTCCCTTTC TACCAGAGTATTTCTGATAGCATACAAGCATGCCATGATACTACCCATCCTAAAATAAAA CTTAAAAAAAAATTCTGCTTTTCACTTCATTCACATAACCCAACCCCAATCACTGCACTG TTTCCACTGGTCCTTTTAGAGGATTCTCCATTTTTATTATCTTTATGTTTCATTTTTTTC TTGTGACTTCTCTAGTTAGTCTTTCTTTCCTACCATTTAACTTGTCGAGATCACTAGTGA CTGCCTTTTTATAGGTCAAGGGGTCATTTTTGAGTCTTATCTTACTGTCCGCTCAACTGC ATTTGATACAGTTGATCTCCTTCCATCCTACTCAAAACTTTTTCTGTGTTTGGCCCCTAA GACAGTATGCTATCCTGGTTCTCCTACCTCACTGACTGTTCTTGCCCCTCTTTGCTGGCG TATTCTCCTGTTTTCACAGGAGTCAGTCCATGGACCTTTTCTCCATTTATATTATTTCTT TATGTGCTTTCATGCTGTCACATGTCTTAAGATTGTCTATAAGCTGATGCTCACATTTTG AACTCAAGTCAACTTCTCCCTTGAGTTTTAGATTTGTGTATCCAGTTGCCTACTTGACAT TTCCACTTGAATATTTATTTATTAAACATACCAAATGTAATATGTCTAAGCGCAGTTTTT TTTCTCTGGTTTCCCCTATTGAAGTGAATGGCAACAGCATTCATGTAATTGCTAATGCCC TAAACTGCAAGGTCATCTTTTATTCTTCTTACTTAAATCCTATATTTAAAATATGAGCAA ATGCTGTTTGCTGCACCTTCAAAATATGTCTTAATAAATATGTCACCTCTCATCATTTGT GACATCACTACTTTAGTACAGTACATCATCATCATCACTCACCTTAAGTAGTGTCCTAAT TGGTCTTTCTGCGTCTCTTCTTCCCCTTAACCCATTGTGTTTTCCACACAACAGCCAGAA TGATTTTTTAAAAACATACTAAATCATGTCAGTTCCTACTGAAAACACTTTCAAGGCTGT CACACTTAAAGAGATTTCTGTAAGACTCTGTATGACCTATCCTCAGAGTTCTCTGTTCCT TGGACTTGCCATACTCCTGTTTCCAGGCTTTAACTCTTGCTGTCTACTTATTCTCCCCCA GGATCTTTCCATGGCACATTTTCTCATTCCATTCAGTCCTTGCTCAAATATCCGCATCAC TAATTGACTCTATATTAGATATTTATTTTGTTTATTGACTGACATGAGCAGAGTCTTCCT CTATTTCATTCATTACTCTATCCTTAGTGCTTAGAATAGTATATTGTTGTCTGGCACTTG GTAGGTGATGCTCAGTAAATTTTTTTTATAATGAATGGTATAAGCTGAGCTGCTAGCTGA GTGCATTAGTCATCTATTGCTGCATGACAGATTGCCACAAACTTAGTGGCTTAGCACAAT GCATGTTTATTACCTCACAGTTTCTTTGGGTGAGGAGTCCAGTCACATTTAGCTGGGTCC TTTGCAAGGCGCTGTAATCAAGGTGTTGGTTAGGGCCAAGGTCTTATCAGAAGCTCAATT AGGGAAGGATCTGCTTCCAAGCCCATGTGATTGTTGACAGATTTAGTTGCTTTCACATAG CCTTCTTTATAGGTAGTTCACATTCATGACAGCTTCTTCAAAGCCAGTAAGGAAGAGAGG GTCTTCTGGTAAGAAGGACATTATATTCTTGTGGAATGTAATCATACATACGCTGTCACC TTTGCCATATTCTGTTGGTTAGAAGGAAGTGATAGGTCATACTCATACTCAAGCAGGGAG AATTACCCAATGGTTTGAATACCTGGAGGTGGGAATCACAGTGGTTACCTTAGAGTCTAT CTGGGTTTCACGTGGAGATGTGTGGTAAAAAGACTGAAAATAACATTGGATGTGGAGACT AGTAGAAAGGATAGCAGATAGCAGTGATTATGCTGTCTGTGAAAGTTCAACTTAAGAGCT TTAGAGTGTCTTTAGACAGTTGGTATGATATGATTCTCAGTTTCTTACTGAGTCCAAGGA AAGCTGATAGCTGAAGGAACTGATGAAGAAAGGAAGATAAAAGGATTTAATAGAGAAGTA TAGGCTGAAAAACTCCCAAGCTTGCTATTTGCTAGGAGGGAGTCTAGGAATTTTATGTAT TCCCCTATAGCCAAAGTGTGACTAGTAGTCAGCCAGCCAATAGAAATGTCTTATTTTTTG TATACATTTTTCTCAGCTATGATTCATTCTATAGAAAAGACTGGGGCATAGCTCTGATAC TTTTAAATAACGGAAAATTTCATGTCTTACTAGTTCAACTATTGGAAAGAGACTATAGAG ACCTCATGTTTCGCCCTGAGCCCAAACTCTTGGGGGAAGGGGCAGATTACCCAGCTAGAT TAGCTTGCTGACCCCCCATGATTAAGCAGCTATGACGCAGAATGGATCACTTCATATTAC CAGTATTAATAAAGTAGTAGAAGGTGGTGGTAGTGATAGTAGTAACAGTGATAGCAATTA ATATTTATTGAGCACTGATGGAATAGTGATTCCTTCATGGGGTTAGAAAAGGGTACTGAC ATTTTACAACCCTTTCAGTTTACTTATGGGTTTATAGATAAGGAAACAAAGACTTAAAAG GGAAGTAACTTAGGCATGCTCACACAGTTAGAATATAGTGGAGTAAGTTTTGCAAAAAGA TAAAAAGATGGAGGATAGTTAGAAAGAGATAATGAACATAAGAAAAATAGAGGGCCAACC TAGGTGGTCCTAGGTGTTTAGTTGAATACAGTGCACCCTAAGCTTTTTGGCACCAGGGTC TAGTTTCATGGAAGACAGTCTTTCCATAGAATTGGTTGGGGGATGGTTTTGGGATTATTC AAGCACATTATATTTATTGTGCACTTTATTTCTATTATTACATTGTAATATGTAATGAAA TAATTATACATTTCACCATAATGTCAAATTAGTGGGAGCCCTGAGCTTGTTTACCTGCAG CTAGGTTGTCTCATCCAGGCATGATGGGAGACAGTGACAGATCATCAGGCATTAGATTCT CATAAGGAGCGCACAACCTAGATCCCTCATATGTGCAGTTGGCGATAGGATTTGCTTTCC TATGAGAATCTCATGCTGCTACTGATCTGACAGGAGGCGGAGTTCAGGCGGTAGTGAGAG CAATGGGGAGTGGCTGGAAATACAGATGAAGCTTCGCTCACTCTCTCTCACCATCACCTC CTGCTGTATGGCCTGGTTCATAAGAGAGCATGAACTGGGGGGGTTAGGGACCCCTGATCT AATAGACAGTATTGTCTATTGATTAAGACTGTGGGTTCTGGAGCCAGGCTTTCTGGATTT GAATCCTGGTTTTACCAAATACTACCTCAAGCCTTAACCTTTCTGAGATTTAGTTTCCTC ATTGTAAAATGGTAATAATACTACCTACCTAATAGGTTGTTATGAGCATTAGATGAGTTG GTGCCTTAAAAAGTACTTGTTAAAACATTAAGTGGCCTGGAATCAGTTTCAAATTAAATA TCAATTCTAATAGAATAATATATTCTGGAAATAGAGCATTGAGGAAGATGGCAGAGAGAA AATTTTCCAAGAAATAATATCAAACACTTCCCCAAACTGAAAATTGAAAGGGCTCAGTGA CCAAGTAATCAGAACAAAGGATAAAAAAAGCCCCACATGAAATTTTTGTATATCATAGAT TAAAAAAAAGATTCTGAAAACTTTCCAGAAAAGAAAGACAGGAAACATATAAAGGACTAG AAATCAGAATACTGGATTTCTCAATGCAGTTCTGGATTCTAGAAGAAAGTAAAGTAGTGC TGTCAAAATTCAGAAGGAAATGTTATCTGCCTGCCGACAAGCAAAAAAAATAAATTTTTA TACATGCAGGAAGTCAAGAAAATTCAACTTTTTACTTTCTCTTAGGACACTAATAGAGGA TGAGGTCCAGGAAATGTGATCCAGCAGTAGAGAAGGGAAGTCCAAGGACTTCAGACTTGT AGGAGACTTGAGCAGTAACCAATATAGGTTGGAACCAAAAGTTGGAAGATCTGGGCCTGG CACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACGAG GTCAGGAGATCGAGACAATCCTGGCTAATACGGTGAAACCCCGTCTCTACTAAAAATACA AAAAATTAGCCAGGCGTGGTGGTCAGCGCCTGTAGTCTCAGCTACTCGGGAGGCTGAGGC AGGAGAATGGCGTGAACCCGGGAGGTGGAGCTTGCAGTGAGCCGAGATGGCGCCAGTGCA CTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAGATGGAAGATCCAAG GGAAAACGTAGAGTGAATAAATTATTTGATTATTTGTTGTATCCAAGAAATAGTAATGAT AGGCGTTTAACAGATCTGTTGGAATTCTGGAAATATTAGTGGAATGTACTTAAAATTAAA CAAATGAAGAAACAAGGCAATGGTTAACTTTAGTAAAAACATTGTTCAAGAAAAAGTAGA CTCATAGTACACTTGATTCAGCAATGAATTACATGTATGTATATATGAATACTGGATATT GATTTAAGCAAAATGTTATATTTAACTCTATTTTGGGGATGGGAGTGGGATAGAATAATA AAAGAATGCTGCCTCATTTGCCCTAAGAGCAAGTCTACAAATAATATCTTGACTAATAAT AGCAATATAAGCATATTATTTAGCAGTACACAAAGTAAATGTTATAAGAGATGGCTAAGA GTTTAAATTTGTTTTCTATAGAAACAGTATATGGGAGGGGGCTAGGAATTGCAGTTTTTG TTATAATCTCTAATAGCATGTCTTTTTTTAAACTGTCCACATATTAACATTATTTTGGAT GATATAAAATAATTTTTTAAAAATCGTGCATAGATAATGTACAAGTGAAAGAGAAGCCAG TGATTTTAGCATACCTCTAAAGAAAAAAAAAAGCAAATTCTTACTGAACTGAATTCCTGA GTAGTTATTTCACTAAGTCTCTCAGATTGCTAGCCTGCTAAATGTAGAAATTCTTGCTGC CTAATGCCCTTCTCTCCAATGGCAGCTGCCTCTTGTTCTGCGAGGGGAATAGCAGTTGTT AACACACAGTAGAACAAAACGATTGTAGTCAGATGTTAACCACATATTTAGTATACTAAT GCAGTAGAATGAAATGAAACAATAGACAAAAATAGCACAAATACTGACTTAACAGAAACA CTGGATTGTTGTGTACATCCCTACTTCAGGGAGGTGAAGTGTGACTTAGGTAGCTTAAAA ACAAACTCATTTTGTTGATGCTGAATGATATCAGAATTAAGTTGAGATTTTTCTAAGTGA AACTACATTGACAGATACAGGACAATTGTTAATGAGATGAGTTGTAAATGTTTGAAGAAT CAGGTTTGTTTCAGTTTCCTGCATGGAAAGGTAATCAGATATTTGAATGTGATTGGTCAC TTGGGTCTTTAGAGAAAGCGAATATTTGAATAAAGTTTATCTCTTAAAAATGTATCTGTT AAAAATGTTTAGACTTTGTTGTGTATATTTTCATTATGGTCATATTTAGAAGACTGATTT TGATTGGAAGGCTTTTACCTAGAGAATATTACCATATTCAATATGGAAAACCGTACTGAA CAACGTAAAACATGAGATCTTTCAAACTAAGAAAGATCAAAGTGTTCATAATTGGAAATG TGGAAGTTTTTAGGGCATTCACATAACAGATTCCAACTTCACTCTGTAGTCTTAACTCCT TGTTCAGTGCGTAGGCCAACTGATTTTCTCATCTCCTCTGCCACCCTCCCCTTCTACCTC TTCCCAGCCCTAGTACTCCCATGTGAAATCCTCCTGTATCTTTAAGGTTCAGTCAGGTAT GTTTTTTTCTTACAGTATTTTGTTTGATTCTCTGCTAGCTGGGAGCGCTCACCTCTGTTT AACTCCTATTGTGTTAAATTCTCTGTTTTATGGTTGTTTTTTAATATCCTTTATCTCATA GAACAGGAGTGGTATCTTTCTCTGGATTTTCTGTCTTCCAGGGTACCTTATGCAGGCTAA ATGCTTACAGAGTTTTGGATTCAGTTTTTATGTAAATAGAGATTCAGGGCTCTATAAAAC AGCCCTTTCTAAAAGTAAATTGTTTTAATAGGTTTACAGTCTTACATGAATCCTTTCTAC CAACCCCTTAGTGTGGATGGGGCATTTGTTTAGTCATTCCTGACAAATGACTTTTGATTT TTGTTTTTCAGTCTTACCTCCAGTATTAGTGCCTCGTCATAATGAATTCAATCCACAACA CAGCCTTCTGGTTCAGTTTAGGAACCTGAGCCACAATGAACCACACATGCCACAAAATGC CACGTTTCCAGATTCTTTCCACCAGCCCAACAACACTCCTTTTCCCTTATCTCCAAACAG CCCTTATCCCCCTTCTCCTGCTAGCAGCACATATCCCAACTCCCCAGCAAGTTCTGGACC AGGAAGTCCATTTCAGCTCCCAGGTAAGACTTTATTTTATTGATACCAAAAAAAAAAAAA TTCCTAAGAATCACAGTTGTTCTTACTGTGGGCCCTCTGGGTGAACTGTTACATGCCAAG GTATAATAGCTGTTTCTGACTCTTTATTCTTTAGGTAATTGTTTGATTTCCAGAAGAGTT TAGATTTTATTTTGCCAATTACCGTATGTTTAAAAAATGGAAGTAGCCCTATTTGACTTA AATATTTTCTTCTATTTTATGACACTCAGTACCATTTATTGTCTTTTATATAACTGATAC TGTGATGAAAGCTATGGCATTCAATTTAATCTTCAGAATGACTATGTGAGATAGATATTC CTGTTTTACAGATGGAAAAAGAAATTCTAAAGTAAATTTTAAACTTTTAAGTACCTTACC TAGGGTAGGGCTAAGAACTAGAGGTTCAGACCCAGGTTTGTCTAACTCTAAAGTCTGTGA TCTTTCACCTTTACTGTGTGGCTTTTCAAATTATTTAAGACTTTAGAAGTTAAAATGAAT CCTGGTTATCTTTAGTTAGATAACTGATGAACTGATTTCACTGGAGAAAGATAAGTAGAT TTTGTAAAGTTCTAAATTTTGTTAATGGCATGTCATATATGGACATGTCAGTATGTCACT GTCAAGAAATATTTGAACACCTGCTGTTGTCAGGCAGAGTCATATATAAGTACAGTAAGT CCTCACTTGATGTCATTGATAACGTCTTGGAAACTGACTTTAACTGAAACAGCATATTAC AAAGCCAGTTTTATCATAGGCTAGTTGATATAAACAAGAGTTAAGTTCTTGTGGTATATT TCTGGTCACAAAAATATCACTAAATTTATAAATAAAGACCCAAGACTCTTCTAATATTAA ACATTGAAATAAATGTGAGCTGTGCATATCTTTAAGAAAGATCAATAAAAACAAGACTGT TATTTACTTAATTATTCTAATTCATGGTCATGGGTAGCCAGAGCACATTCCAGCAACTCA GGGCACAAGGTGGAAACCAATCCTGAATGGGACGTGATTAAATCACAGAGTGCACTCACA CACACCCCGGCACTCACACTGGGACTGTTTAGACATGCATGCCAGTTCATCTGATGTGCA CATCTTTGGGATGTGAGAGGAAACTCGGGTAACCAGAGAAAACTCAAACAAACATGGGGA GAATGTTCAGACTCACACAGACGTGGCCCTGGCTGGGAATGGATTTTTTTTCTCATCAGC ATCATAACAAAATGATGCTGAACAAAACACCATTGAACAAAACATTATTCAAGGACCTAC AGTATATTCTTTGTGATTTCTCTACTGCAGCAAAATATCAATTGGTATAGTTTTTTCTTT TGAAGAGAAATTAAGTGCCAGCTGTTTAACTTGCTATTAGGAATTTGCTCAAAAACAAAT TTTCATAGTTTGTCTTAGATTCAGTGCTAATTGTAGTTCTGTCTCAAAATACATCCTGTA CAAAACATTGGGATGAAAGACAAATTCGGTTCTTATTTATAATTACTGAGACAAAAAAGT ATAGCTGTAGCTTTTGCAAAATTTTCAACTATGAGTGTTGAAACTCAAAGATTTTCTAGT TAACATTTAGTTTCCTAAGTGAATTACCTAACCATTTAATAGGACACAACAGCCATATTT GGATGTTGCACAAGCGTTAGACAATTGCTGTTAGTGTTGATGGCAAATTTTGAAGGGACA TAGTTTTACTTTCCAGTTTTAAATGACAGTATACAGTATGTGCTGATCTTAATAATTTAA AAGTGTCTCTGTAGTAGATATATACCCAAATGAGGAAAATCTGTACTTCAGATTGATATG TAATAGCTGTAGTTTCTCTGAACACATAAAAATAAAGGCAAAATTCTTGACCTTGAATTC TGTTTCAGTGAATTTTAGGACTGATCCTTGTATCCTGGATTACCAGGGATCTGGGCTAAA TAAATGTGGATTTGTAGTAGGTTTTCAATTGCCATTAGGTGTGCTGTCTGTTCTCCTTTT CCCTTGCCCTAGGATAGTATCCTACATTTTTTTGTGTGTGATGTTCAGTAATGAAGCTTG CTGGTAATCTTAAGAATTTTCTAAAGCTTTTAGAGTAATAATTTTGAGCAGAATGAAGAT TTTAATTATTATTTTTTTTCCTCTTAGCTGATACGCCTCCTCCTGCCTATATGCCACCTG ATGATCAGATGGGTCAAGATAATTCCCAGCCTATGGATACAAGCAATAATATGATTCCTC AGATTATGCCCAGTATATCCAGCAGGGGTAAGAGAAGTACTCACTTCATTTATTTTATAG TAGTAGTTGTTTTTAACTTATTGGCTACTTTTTTAAAAACAGCTTTATTGAGGTATAATT TATATGCTATAAAATTTTTTTGTTTTAAGTGTATGATTCAAAGATTTTGGTAAATACACC AAGTTTTGCACCACAGTCTAGGTTTAGAATATTTCCCTAACTCTTTAAAAAGGTTTCTCT GCGTATTTGCAGTCTATCCTCACTCCTATCCTCAGCTCCACATACCCTCTAATCTGTTTT CTGTACCTGTAGATTTTATCTTTTCTGAACATTTTATATAATTGGAATCATGTAATAATG TAGTCTTCTTTCACTTAGCATGTTTTTTCAAGGTTCATCCGTGTTGTAGCATGTATCAAT AGTTTGTTCCTTTTTATTGCTTAACAGTACTCCTTTATATAAATATATCACATTTATTCA CCAGTCAGTGGGCATTTGAATTGTTTCCGTATTTTGATTATTATAAACATTTGCAGCTGG GCTCAGTGGCTCACGCCTGTAATCGTAGCACTTTGGGAGGCCAAGGCGGGTGGATCCCTT GAGATCTGGAGTTCAAAACCCCAGCCTGGCCAATATGGTGAAACCCCGTCTCTACTAAAA ATACAATAAAAATAAAAAATTACCTGGGTGTGGTGGCAGATGCCTGTAATCCCAGCTACT CTGGAGGCTGAGACAGGAGAATCACTTGAACCCAGGAGGCTGAGGTTGCAGTGAGCTGAG AGTGGAGTGCCACTGCACTCCAGTCTGAGCAACAGAGCGAGGCTCCATCTCAAAAAAACA AACAAAAATCGCATGTAAGTCTTTTTGTGGATATTGTTTTATTTCTCTTGGATAGATATC TAGGAGTGCAATTGCTGAATAACATGGTAAGTTTAACTACTTAAGAAAACTATAAAACTT CTCTGAAGCGGCAGTACCATTTTACATTCTCACCAGCAAAGTATGAGGGTTCTATTTTCT CTGCATCCTCCTAACACCTGTTATTGTCTGGCTTTTTAATTATAGCCATTCTAGTGGGTG TAAAGTGCTTATTGTGGTTTTAATTTGCATTTCTCTAATGAGCAATGATGAGCATTTTTT AAATGTACTTGTTGGCCATTTATATATCTTCTTTGATGTGTTTATTTTAAATCTTTTGCC CATTGGGTTGTCTTACTGAGTTGTAAGAATTTTTTGTATATTCTGGATATGAATCCTTTA TCAGATATATGATTTGCAAATATTTTCTCTCAGTCTGTGGATTTCTTTTCATTTTCTTAA TGACGTCTTTTTGAGGGTAATAGCTTTAAATTTTGATGAAATCCATTTTGTCAGTTTTTT CATTTCTAGATTATGCTTTTGGTGTTGAATTCAAGAAATTTTTGTCTATCCCAAGGTCAT GAAAATATTATTTTATGTTTTATTTTAGAAGTTCTATAGTTTTAGCTCTTATATTAGGTC AGTGGTTCCTTTTGAGTTAAGTTTGTATGTGGTATATGGTAAATGTCTACATTAAGTTTT TTGCATATAGAAATCCAGTTGGCTTTGCCATTTGTTGAAAAGAGTATCATTTCTTTGTTG AATTAACATCTTTGTCAGAAATCAATTGACTGTAAATGCCAGGGTTTATTTCAGGACTCT GTTGGCTTACATATCTATACCTCATAGTCTTGATTGCTAAAGCTTTCCTATAAAGGTTTT TCCCCCTATTTTTTTGTTGTTTTGTTTTATTTTTAATTTTTAAATTATTTATTTATTTTA GAGACAGAGTCTTGCTCTGTCATGTCCAGACTGGAGTGCAGTGGCGTGATCATAGCTCAC TGGAGCCTCAGACTCCTGGGCTGAAGTGCTCCTCCACCTTAGCATCCTGAGTAGCTGGGA CTACAGGCATGCATCACCATGCTTGGCCAATTTTTTTGTTGTTGTTGAGATGGAGTCTTA CAGTGTTGCCCAGGCTGGCCCTGTTTTTTTTTGTTTGTTTGTTTGTTTTTTTATGGCAAA CTATATATAACATAAATTTTACCATCTTAACTATTTTTAAGTGTACAGTTCAGTGGCATT AAATCCATTTATAATGTTGTGTGACCATCACCACCATCCATTTCTATAGCTCTTTTCACC TTGTAGTATTGAAACTATACCTGTTAAATAAAAATTTCCTATTCTCCTTTTCCCCCAGCC CTTGGCAACCACCACTCTGCTTTCTAATCTCTATGATTTTGACCACTCTAAGTACTTCAT ATAAATGGAATCATACAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGTGAC TGGCTTATTTTTCCTCAGGGCACATCCATATTGTAGCAATGTCAGAATTTCATTTCTTTT TAAGGTTGAGTAATATTCCGTTGTATGTATATACCAAATTTTGTTTATCTATTCATCCAT TGATAGACACTTGGATTGCTTTCACTTTTTTGGCTATTGTGAATAATACTACTGTGGACA TGGGCGTACACATATCTCTTCGAGATCCTGCTTTCATTTCTTTTGAGTATATACCAGAAG TACAATTACTGGATTACATGGTAATTATATTTATACTTTTTTGAGGAACAGCCATACTGT TTTCCACAGTGGATGTACCATTTTATATTCTCAGCAACAGTGCACACGGATTCCATATTC TTCACATCCTCACCAGCACTTGTTTTCTATTTTTTAGATATTGACCATTTTAATGGGTAT GAAGAGATATCTCACTGTGGGTTGTTCTGTATTTTTTTTATCTTTTTTTTTTTTTGGATA ATTGACAAATGAAAAATTGTATATCTTTATGGTGTCATTGTGGCTTTAATGCCACTTTGG TTTGAGACCTTAACCTCCTTAGTTTGTCCCAAGTTTAGAAATATGTACTGCTATTTTATA CGTTTCTTAAAACAATGTGTTTTTATGTGTTTTCTATGTTTGTGATAATACTGAATGTGT GTTATATTGAGTGCTCTGTATTCCTAAGAGCAGTTAAATTTCCAGACCCCTAATAGTTTT GTTAATGTTTCTATAATGTCTAGAATTTATCAAGAAATCTCATTATATTAATTTGCCTAT AATTTAAAATCTACCTTCATTTACCATAAAAATGGAACATGAATTTCTGGATTTGAATTC CTGTTTCTCTACTTATTTGCTTTGCAATGTAGGTAGTTTTTAAATCTCTAAGCCTGAGAT TCCCCATTTACAAAATAGGGATGATATGCTGGAATTATTAATATGTTGATTAAATTAGAC AATACATGTAATGATTTTAGCACACAACATTAGGCCGTACACAATAAATAGTATTATTTT TCTCCTTTTAAAAATATGGACTGTATTTACTCCACTTTATTCTCCTTTTGAAAATATGGA CTGTATTTACTCCACTTAACCTCCTTTTCTTTTCTCCTGATTTTCCAGAGATCATAGTGC CATTTAATAGTGTTATATGTTAGATGTCCATTGGAATGTAATTTGTCTCAACCAAACAAC TGAGCCCCTTTAGAGGAACTTGATACTCACATTTTCTCACCTTTGTAGATACCTTTTTCA CTAGAATTTCTTCTCATTTCAGTCAGATTATGTGTATTTTCTCCTTTCTTTTTGCCAAAA AAGTGACAAAAAGAAAATCAAAGTTAAACGGCAGTGCCTGGAACCACCTGTTAGCAACAA TACGTCTTCTGCCTTGAGCAGAGGCAGTGCTTTTCTGGTTCCTCTTTTCCTTTTAACCAA AATTGCCTTTTTAGTTTCGCCTAGCATTTTTTTTTTTCTATAACCTTCTGCTCGTTCTTA GCTCTAATCTTCCTGATGTTACTCTTATAACTTCATGCAACTCATTTGTACCTGTCTTTA GGAATGGGCCTCTACATGTATAAACTTTGTATAAACTTTAAAATCTGAGCTCTTAAGACT TCTTTGGGCTTACAGTGGTTTATTTTCCTCTCTTCCTTCTCATCTGCATTCTTTGCCATT GAATACTCAGAATTGATTTATTTTCCTCTCTTTCTTCTCATCTGAATTCTTTGCCATATA AAACTCAGAATTGAGTTTTAAAAGTTAAACTATTCTATTAAAAAAATAGTTGGCTGGGCG CAGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCATCTGAG GCTCAGGAGTTTGAGACCAGCCTGGCCAACATAGTGAAATCCCATCTCTACTAAAATACA AAAATTAGCCGGGCTTGCTGGTGGGTGCTTGTAATCCCACCTGCTCGGGAGGCTGAGGCT GGAGAATCACTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCATGCTACTGTGC TCAATCATGGATGACAGAGCGAGATTCCATCTCAAAAAAAAAAAAAAAAAAGTTAACCAA TTATTTTAAATTGCCTACATAGACCATGTGATTACTCTTACATTTTCCTTGGTGTTATTT TATTCCTGCCCCTTTTTTTTTGAGACGGAATCTCGCTCTGCCACCCGGGATTGAATACAG CGGCACAATTCGCTCACAGTTCTCCTGCCTCAGCCTCCGACTAGCTGGGATTATCATACG CATGTGCCACCACACCCGGCTAATTTTTGTATTTTTAATAGAGACGGAGTTTCACCATGT TGGCCAGGTTGGTCTTGAACTCCTGACCTCACATGATCTGCCCACCTTGGCCTCCCAAAG TGCTGGGATTACCGGTGTGAGCCACCGCACCCAGCCATATTCCTGCCTTTTTTGAAAGAG AATTGAGGGTCTGTGATTTCTTTGCTTGATTTCAGCTCCAGGAAGGGTGCTGGGATGTAG AGCTTCCATGTATCTCTTCTACCCTTTGTGTCTATTATGAGTTACTGACTTTTATATTAA TGAGTTTGGCCAGTATTTTATATTGTGTATAAACCTTTTTCTGTAGGCAGTTCTGGCATG TAAAATTTAAACATATACCTCTATTTACCCAAAGATAATGTTCATTTAGTTGTTTTGTTT TTTTGTTTTTCTTTATAAATAGACTGCATTTTTTAGTTCAGTTTTTGGTTCACAGCAAAA TTAAGTGGAAGGTACAGAAAGTTCTCACATACTCTCTTCTCCCACACAGGCACAGCCTCC TCCATTATCAGCATCTCTCACCAGAGTGGGACATTTGTTATAGTCAGTGAGCTTCCATTG ACACATGATTATTATCCAGTGGGGTTCATTCTTGGTTTTGTACATTCTGTGGGTTTTTAA CACATGTATCCACCCTTATGATATGATACAGAATCATTTTTTACCTCTTAAAAATTCTCT GTGCTCTGCCTGTTCACCTCTTCTTCCCCACAACCCCTTGCAACCACTGATCTTTTTACT GTCTCTATAGTTTTGCCTTTTGCAAAATGTCATAGTTAGAATCATACAGTATGTAGCTTT TTCAGACTGGCTTCTTTCACTTAGTAATATGCATTTAAGTTTCTCCATGTCTTTTTATGG CTTGATAGCTCATTTCTTTTTAGCATCTCTATTAGGGTTCTCTAGAGGGACAGAACTAAT AGGATATATGTAATATATATGAAAGGGAGTTTATTAAGGAGAATTGACTCATGTGATCAC AAGGTAAAGTCCCACGATAGGCCATCTGCAAGTTGAGGAACAAGGAAGCCAGGGGTGGAT CAGTCCAAGCCCAAAACCTCAAAAGTAGGGAACCTGACAGTGCAGCCTTCAGTCTGTGGC CAAAGGCTCAAGAGCCCCTGGCAAACCACTAGTCTAAGTCCAAGAGTCCAGAAGCTGAAG AATTTGAGTCTGATGTTTGAGGACAGGAAGCATCCAGCACAGGAGAAAGATGAAGGCCGG AAGACTCAGCAAGTCTGCTCTTCCATCTTCTGCCTGCCTGCTTTATCCTAGCCACGCTGG CAGCTGATTAGATGGTGCCTACCCAGATTGAGGGTGGGCCTGCCTCTCCCAGTCCACTGA CTCAAATGTTAATCTCCTTTGGCGACACACCCACAGACACACCCAAGAAACAATACTTTG CATCCTTCAATCCAATTAGTTTGACACTCAATACTAACCATCACAGCACCAAATACTATT TCATTGTCTTGGTTGTACCACAGTTTGTTTATCTGTTCACCTGCTGAAGAACCTTTTGGT TGCTTCTAAGTTTGAGCAATTATGAGTAAAGCTGGTATAAACATTCATGTGCAGATTTTT TATGTGGATATAGTTTTCATCTCATTTGAATAAGAAGCATGATTGCCAAATTTTATGGTA GGAGTATGTTTAGGTTTGTAAGAAACGGCCAAAGTGCCTTCTAAAATGGCTGTATCATTT TGCATTCCCAACTATGAATGAGAATTCCTGATGCTCCTCATCCTTACCAACATTTGATGT TGTCATTGTTTTGGATTTTGGCCATTCTAATAGGTGTGTAGTAGTATCTCATAGTTGTTT TAATTTGCAATTCCTTAATGACATAACATGTTGAACATCTTTTCACATGCTTACTTGACC AATCTGTGAGTCTGTGGTGGGCTCCCTACTCATATCTTTTGCCATACTTTAATCAGATTG TTTTTGAGTTCTTTGTATATTTTGAATTATAGTCTTTTATCAGATAGAACTTTTTCAGAT TTTTTTTTTCCTAATCTGTGGCTTGTCTCCTCATTCTCTAGACAATGTCTTTCTCAGAGC AAAAGTTTTAAATTTTAATGAAGGCCAGCTTATCAATTATTTCTTCCATGAATTGTACCT AAAAAAAGGCATCATCATACCAGAAGTCATCTAGATTTTCTCCTGTATTATTTTCTAGGA GTTTTATAGTTTTGCATTTTACATTTAGGTCTGTAATCCATCTTGGGTCAATTTTGTGAA GAGTGTAAGGTCTAGTCTAGATTTACTTTTTTGATGTAGCTGTCCAGTTGTTTCCTGTAT CATTTTTTGAAAAGATTTTTTTTTCTTCCATTGTATTGTCTTTGCTCCTTTGTCAAATAC CAGTTGACTGTATTTACTTGGGTCTATTTCTAAACTCTATTCTGCTCCTTTGATCTGTTT GTCTGTTCTTTTATTTTATCATGATCTTGATTACTGTATCTTTATAGTAAGTCTTAAAGT GAAGTAGTGTCAGTCCTCCGACTTCATTCTTCTCCTTTGATATTGTGTTGGCTATTTTGA GGCTTTTACCTCCCCATATAAAGTACAGAATCATTTTGTCTATATCCAAAAAATAGCTTG CAGGGATTTTGATTGGCATTATTACTCTATAGATTAAGCTGGGAAACACTGCTATCTTGA CGATATTGAGTCTTATTCTTGAATGTGCAGTATTTCTCCATTTATTTAGTTCTTTGATTT CTTTCATCAGAGTTTTGTAGTCTTCCTCATAGAGCATGTTCCTATTTTTTTATATTTGTG CCTAAGTATTTAATTTTGGGGATACTAATGTAAATTATAATTTTTTTATTTTAAATTTCA TTTGTTTATTGTTGCTGTATAGGAGAGCAATCAACTTTTGCTTATTAACCTTGTATCCTG CAACCTTGCTATAATGCTTACTAGTTCCAGGAATTTTTTGGTCAGTTCTTTCTTATTTTT ACATAGACAATCATGTAATTTGCAAACAAAGACAATTTCCTCCTTTCCTATCTGTGTACC TTTTATTTATTTATGGCATTAGCAAGGACTTCCAGTATGATGTTGAAAAGTGGGAGAGGA GGCATCTTTGCTTTGTTTTTGATCTTAGCAGAAAACCTTCTAGTTTCCTACCATTAAGTA TGATGTTAGCTGTAGATGTTCCGTATCAAGCTGAGGAAGTTCCCCTCTATTCCTAATTTG CTGAGTCTCACTTAGTTTTTTAGTTTAACTTTTTTGTTTAAAATAATTTTACAGATACTG ATTATAGTTAAATCCTTCAGGTCTCTGAAAAAGAATTTTTTGTCTCAAATTTAAACCTGA ATTAGTTTATGTTAGAAAAACAATTAAAAATGTGTTGTTGCTGCTATGTTCTGAATTGTG TCGTCCCAAAATTCATGTTTTGAACCAAGGCCTGGGCACCTCCTCACTCCACCCAGAGGG TTGGGAGGGTAGAACATCAAACCAAAGAGGTTTATTCTCCAGCCTTAAGGCCTAATGCAA TTTGCTTTGCTAGGTTTTCAGCTTCCTTGACCCATCATCACTCCCTTATTTTTTGTTTTT CCATTTTGGAATGGGAACGTCTATCCTGTGTCTGTCCCACCATAAGCACGTAACTTACCT GGTTTCATAGGTTTACAGCTGGAAAGGAATTTTGCCTCAAGTCTCGTATGTCATATGTAG ATGATATTTGGATGATACTGGGTTTACAACATTAGAGTTGATGTGGAAATGAGTTAAGAC TTCAGGGGCTGTTGGGATAGAATATATGTGTGTATTTTACATGTAAGAATGATGTGAATT TTGGGTTGCTGGGGTGGAATGCTAATGGACCATATTGAATCTCCCTAAAATTCATATGTT GAAGTCCTAACTACCAGTGTGATGGTATTTGAAGATGGAAATAATTAGGCTTGAGAGTGG GATTGTCATAATGAGATTAGTTCCCTTATAAGAAGAGGAAAAGAAACAGATCTTTCTCTA AGAGCATGCACTGAGGAGGGGCCATATGAGCACACAGTGAGAAAGCAGCTGTCTGCAAGC CAGGAAGCAGGTCCTCACTAGTTACCAAATCTTCTGGCACCTTGATCTTGGACTTCCCAG CCCCCAGACCTGTGAGAAATAAATTTCTGTTGTTTAAGCCACTCAGCCTTACGGTATTTT ATAGCCTGAGCAAGCTACGACTATTGCCGATCCTGGTATTTCTATAACTTTTTAAATTGT CATATTCAAGCTGATTTCTAGTGCTTGTTTTCGGATATAGATTCACAGCTAGGAAGGACA GTGAGACTTGTGAAATATCTGAAAATTTTCTTTTTCATGTAATACTTGGGTTGGGTTAAA AGATAAACACATGGACAATCTGAGTTTCTGATATGTATTAAACTCTTTCTGTGTCTGGTT TGTTCACAGATGTTCAGCCTGTTGCCTATGAAGAGCCTAAACATTGGTGTTCAATAGTCT ACTATGAATTAAACAATCGTGTTGGAGAAGCTTTTCATGCATCTTCTACTAGTGTGTTAG TAGATGGATTCACAGATCCTTCAAATAACAAAAGTAGATTCTGCTTGGGTTTGTTGTCAA ATGTTAATCGTAATTCGACAATTGAAAACACTAGGCGACATATTGGAAAAGGTAATCTTG TCATTTTCCTACATTTAATCGAATTCAATCATTTGTTGTACTTGCCATGAACCATGCATT GTGAAAGGTGCTAGAAACATACAAAGAAGTTTGACACGTGGCCTCTGCCTTAAGTTGCCG ATATTGAAGAATGTATTAATCAAATAAAGACATGATGTTCCCTCATTTTTTTGTCCTGCT TAGTGTTTCTTCCCAGTGCTAAGGATCTGAAATCATACTACCACTTTGTTTTTTGAGTGT TACCCTGACTGGAACATAAGCTGTACAGGAACTTGCTTTGTTCACAGCAGTATCCCCAGT AGCTAGAAGAGTGCCTCATTGTAAATACACAACACATATTTATGGAATATTGTGTATGAA TGCTGGTGAAGGATTAGAATTTTATAATTAAGGTATTTGTGGAGTATTTTGGGTTGAGAT GACTTGTAAGTGTTACCATGATGTGAGAGGAGCGGAATTAGAAATGGGAAATCTAGTGTG AATGATACTCCAGTGGCTTCACCACCACTGCTCCCATCTTTTAAATTTAGGCAATAAGGT TTTATTAATAATTCATCCTGCAGATAGTTGCCATAACAAACCGGGCCCTTTTCATACTGC AATAAAATGTCAAAGTCTCATGCATCAAGTGATCAGGAAGGAAACCCATCCCAGGTAAAG TGTATTGCCTGTTTCTTGAGAAGTTTTGTTTTTACCCCTTGCTGCATTTTGCTTCTTTAA CTTGAGGGCATCTTGGTCCAAAATAGGAATAAAAGGTAAATAAATATAATTGTGATAGGA TTTCTTATAGAAGTGATTCAAAAAAATCCTGCGGCCAAAAATAAGTTACGAAACAAAGTT TTCATTGTCTTGAGTTTACTGCCAACTTGCCTTAGTTTTTTCAGTGAAGTGCCTCACTTC TAGGCATTGATTTTTTTTTTCTTCCATCACAGTAGAAGTAATTTAAGGGAAATCTATTTT GTGAATTTTGAAATTCTAGAATCAGTTTTTTCTTTTTCCCCAGCATATAGTTCTAGGACC TTTTCTTTCATGGGTTAGTTTTGGGGTGGTGGAGGGATATGTTGGGAAAATACTAGGTGA CTAGCTTTAGTTATATAATTTGAATATTTAATGTTAAAACTATTTCCACATATTTATATA TTTTTAAAATTTTTATTTTTTTTGCCCTCACATCTTGCAAAGGAACATATATATTTTTAA ATATAAAAAAATTTTAAGTAAGATAAATCTGCCATTTCAAAGCTCTTCTTATGACCTGAA ATTATATATGTAACTTTGGTTTTTTTTTAGTGTTGCTGTCCTCTTTGTTAGCACAAAGAG TGCAAAAGTCTGTCAAATGACTGTTTATGATAGTTGATAGCACTGAGGATTTATTTGAAA GGACTCATCAAAAGATGATTTGGGGTTTTTTTTTTTTAGCCCTCTCTTTCTCTCATAGAG ATGATAAATGATTGTTGGGAAAGGAAAAAGAGAACAACCTAAAAATGGATAACTTAATCT GCTGCCTATTTGAGGCTTCTCTTGTAGATGCAGGCAGACATTAACCTCTTGATTATCTTT GGCAGCAGAAGGCCATCTAGTGGTAACTTCTGTCTAAAGACTGCTGGAAGTTTGCTGTGG ATTAATGGGTACTTTTGTTGCACCATACAGTCTATTTGGTTTCATTGTAATGATTCTTTT AGCTGACTCTTGTGATGTTTGTCTTTTTAAGGTGTTCATCTGTACTATGTTGGTGGAGAG GTGTATGCGGAATGCCTCAGTGACAGCAGCATATTTGTACAGAGTAGGAACTGCAACTTT CATCATGGCTTTCATCCCACCACTGTCTGTAAGATTCCCAGCAGCTGCAGCCTCAAAATT TTTAACAATCAGGAGTTTGCTCAGCTTCTGGCTCAATCTGTCAACCATGGGTTTGAGGCA GTATATGAGCTCACCAAAATGTGTACCATTCGGATGAGTTTTGTCAAGGTGAGTTGTGAC CTCTAACATAATTTGAGTCACTATAAATGTGTATATTATGACTTTAGGTTATAATTTTTA AAAATTGTTAAATGAAAGTTGATAATTGCTTTTGGCCTGATTTAACAGGTTTTTAAATAA AATTATTGAATTTGTAATTTTAACTACATAATAGATCTAAGATTTCATTTTGTAATCTAG ACATTATAAAATGCATGATTGATATTGATTTTGATATTGAATAGGGGCTGAGATTATAAG GAATTTTAGTTAAAAGACTAAATTTCTAGAAAGCATTTGTATTAGTCCATTTTCATGCTG CTAATAGACATACTCAAGACTGGGTAATTTATGAAGAAAAAGAGGTTTAATGAACTCACA GTTCCACGTGGCTGGGGAAGCCTCACAATCATGGCGGAAGGTGAAGGAGGAGCAAAGTCA TATCTTACATGGCGGCAGGCAAGAGAGAATGAGAGCCAAATGAAAGGGGAAACCCCTTAT AAAACTATCGGATCTTATGAGACTTTATTCACTACTGTGAGAACAGTATGGGGGAAACTG CCCCCATGATTCAGTTATCTCCCACTGGGTCCTTTCCACAACATGTGGGAATTATGGGAG CTACAATTTAAGATGAGATTTGGGTGAGGACACAGCCAAATCATATCAGCATTTAATATT AAAATTGCTATTTGAGTCTCTTAACTTCAACAGTTTTGATTATTATTACTAGATTTCATT AGGGTGACTTGGCAGAATTCTTTAGAATACTAAAATTATTTCATTCCTAGCTAAGTACTG TTATTAAAAGTAATGGCAGAAGCCACAATTACTTTTCCACCAACCTTAATATTAAGGATT TGCAAAGTTCAAAGGAACTTTTCAAGTTTTTCATCTACTCTCTTCACCTGACTGTATTGA CATTCCAAAGATTTGTGCTTAAAATCTGAAAAGAATTTTAGTCATGTATTTAAGCAATCT GTACTGTATCTACATATTTAAGCAATCTGTACTGTATCTACATGGTTCTTAAGAATTTAG CACAAGAAGAGCACCTGTCACACGCTGTGCATGGGTTTTTTTCTTTTTGGTATTCAGCCC CAGTCCAGTGTTTTCATGATACTTTGCTGTAGATCTATTGTATACATCAGTTTACTGGTT ACCCTGAAGGTATTTCTGCCTTCTTGTACAGTAATGTGACTTTTGCATATTTATTTTAAT CTCCACTCCCCAATGTTCTTCACTCCCCTGACCGCCCTCCCTCCCCAACCCAGTTTTCCT GGGCCAAGACTACCATAAGCAGTAAACCAGAGAACCTGATAAATCCAGGAAAATAAAAGT GAAAAATTTCTATTTCAATTTTTATCTGCAGTTTTAGGCTAAAGATTTCAGCTCAGTTCA TCCCAGTAATTTCCAACCTTAAAGGATAATCACTATGTGACTGCCACATTAAATTATACA TGCATGTATTGATCAATATCTACAATGCCTTATCTGATATTCAAACAACTTGAAAATAAA AAATTTTTCGTTAAAAAAAAAAACCTGGGCCGGGTGAGGTGGCTCACACCTGTAATCCCA GCACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGATCAGGAGTTCGAGACCAGCCTAG CCAACATGGTGAAACCCTGTCTCTACTAAAAAATACAAAAATTAGCCGGGCATGGTGGTG GGTGCCTGTAATCCCAGCTACTAGGGAGGCTGAGACAGGAGAATTGTTTGAACCTGGGAG GCGGAGGTTGCAGTTAGCCAAGATTGCGCCATTGCATTCCAGCCTGGGCAACAAGAGAGA AACTCTGTCTCACAAAAAAAAAAAAAAAAAAAAAAAAAAGAAACTCTGACATGTGACATG ATCTTACATGAGGCTATTTATGATTTTGATTTTGATTTTTTATATATGATTCCTTTATTA GTATTTAAGTGACATCTCTTTACATTTTTTAGTGGTTTCTCCAGGAATTACCACGTTATC TTTAACATACCCCAATCTACCTAGAGTTAATATTGTACTATTTTTAGAATGTAAAATATG AAAACCTTGCTGTTGAAGAGTTTTAATTACCTTCTTTTATTCTTTGTGCTATTCATAAAT TTTACATCTGCACATTATATCTTATAATACAGTTAAAATTTTTCCTTTAAATAGTCATTA AGTCTTACAAAGAAATTAAGAGAAAATGGTATTTATAAATATTTGCAGGCAGATTCTTTG GGGCTATGTAAATACACTGTTTCTCCTTTATATTTTACCCACAATTTTTGCATTCTTCAA TATATCTTGTCTACAGTAATTATTACTGTGGTGTTCTAGTGGTGATTTTCTATTTTGCAT TTATCCCATTAAGGGAGAATGTATCTCAGATCAGAAATATTTGTTTTAATTATGAGATAC TGTACTGTGTTACCTTTCTAAGATTAAAAAAAATTATGAACTATAACTGGCTCTAAGGGT TTCTTTTAAGGGAATTATATATTATTTTAGAATTCATGAATCTTTAAATAATGTAGCTGT TGTCTTTTAATTTCATGGTGAATACTAAGACTGGTTTTGTGATAGTTATTCTCTTTATGT AACTTCTACATATCTCTACTGTTAAAAGCTATCTTTTTCTTATGGTAAAATTGGTTTAGA GTGGTTGACAGTTTAAAGAGGGATTTGTGATGATATCTGTTCATTTTCATAGGGTTGGGG AGCAGAATATCACCGGCAGGATGTAACCAGCACCCCATGTTGGATTGAGATTATCTTCAT GGGCCTCTTCAGTGGCTGGATAAAGTCCTTACTCAGATGGGCTCCCCTCTGAACCCCATA TCTTCTGTTTCATAATGCAGAAGTATTCTTTTCAATTATATTGTTAGTGGACTTGTTTTA ATTTTAGAGAAACTTTGAGTACAGATACTGTGAGCTTACATTGAAAACAGATATTACAGC TTATTTTTTTCTACATAATTGTGACCAATACATTTGTATTTTGTGATGAATCTACATTTG TTTGTATTCATGTTCATGTGATTAACTCTTAGAAGTGTTGTAAAAGATGCAGAGTAAGTA TTATGCCCCAGTTCAGAAATTTGGCATTGATCTTAAACTGGAACATGCTTTTACTTTATT GCCCTAACAATTTTTTATTAAATTTATTTGAAAATGCATCACATGATGAAAAATTATAGT AGCTTATAAGAGGGCATATACAGTGAAGAGTAAGTTTTCCCTCCTACTCTCGATCTTCCA GAAGCTGTACTTTTACCAGTTTCTTTGTCCCACCAACTTAAAAAAAAAAAGTACAATTCA TTGTTTTGCAAAAGTGTATGGTAGGGGCTTAAAAGAAACTATAAAGTTTTATTTGAATGA ACACTATGCACTGCTGTAACTGGTAGTGTTCAGTAAAAGCAAAATGATAGTTTTCTAGAT GACATAAAATTTACATTTAATACAGATAAGTGTTCTTCAGTGTAATGTGACTTCATGCTA TATATCTTTTGTAAGACATTTCCTTTTTTAAAAAAATTTTTGCAAATAACTGATCTCAAG TATATGTCATTTACTCAAAATCTGTCATAAGCATTACTTTATAGCTAGTGACAGTGCATG CACAGCCTTGTTCAACTATGTTTGCTGCTTTTGGACAATGTTGCAAGAACTCTATTTTTG ACATGCATTAATCTTTTATTTTGCACTTTTATGGGTGACAGTTTTTAGCATAACCTTTGA TAAAATACACTCAAGTGACTTGGACTTAGATGCTTATCCTTACGTCCTTGGTACCTTTTT TGTATTAACAAACACTGCAATTTATAGATTACATTTGTAGGAAGTTATGCTTTTTTCTGG TTTTTGTTTTACTTTCAACCTAGGTTATAAGACTGTTATTCTATAGCTCCAACTTAAGGT GCCTTTTTAATTCCCTACAGTTTTATGGGTGTTATCAGTGCTGGAGAATCATGTAGTTAA TCCCATTGCTCTTACAAGTGTCAGCTTACTTGTATCAGCCTCCCTACGCAAGGACCTATG CACTGGAGCCGTAGGAGGCTCTTCAGTTGGGCCCCAAGGATAAGGCTACTGATTTGATAC TAAATGAATCAGCAGTGGATGTAGGGATAGCTGATTTTAAAACACTCGGCTGGGCACAGT GGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCATGATGTCAGG AGTTTGAGACCAGCCTGGCCAATATGGTGAAACCCTGTCTCTACAAAAAATACAAAAATT AGCTGGGCATGGTGGTGCGTGCCTGAAGTCCCAGCTACTCGGGAAGCTGAGGCAGAAGAA TCACTTGAACCTGGGAGGCGGAGGTTGTGGTGAGCCGAGATCGCACCACTGCACTCCAGC CTGGGCGACAGAGCGAGACTCTGCCTCAAAAAACAAAACAAAACAAAACACTCACCCATC AACGAATATAGACTCTTCTCTCATTTATCGATGATCCTCTTTTTCCATTTTTTAAGTACT TATGTGGAAGCTAGTCTCCCAAAACACAATCTTTAGAGAGAAAAGACATGAACGAACTCC AAAATATCCATTTAATCAATCATGTTTTTGGCTTTGGATAAAGAACTTTGAACCAGTTTT TTTCTCAGGAGCTGTCAAATGGACACTTAATTATGACATGAGAATGAAGAAATTATTTTG GAAAAAAAAAATGACCTAATTTACCTATCAGTGAAAGCTTTATTTTCTGGTGCCTTTTGA AAGTATATGGAGTCATATCATTCTTCTGTTTAAAATGTTAGTTTGGTTTGACTTTCCACT TTGTCCTTTCTGCTCTTGTGAAGAAAAAAAAAAGCATTTTCGAGGAAAGAATTATGCAAT TTCTTTTGTTTTCTGTGTCATTATTTATTGCTTTTTCAATGTGCAGCCAGTGGATGGTTT TAGTTCTTTCAGATGAACTGCCATTTGTGTTTCAGCTCACAGTTCTTTGCTGGGTAAAAG AAATACTTTCTGACAGTCACCTGAGCCTTAAATGTAAGTATTACATGACATGCATTCTGT TTCTTCCAGAGTTCTGTCTGCCACACGAAAGAGAATATTTGCTTACTTGATAGAACTTTG GCATTTTCATCATTCTTTTACTTAACCAGGCTTATGGCATGATCTCTGGAACAAATTTGT AGGAAAAAATTACTCCAATTGAATGACTGATGTATGTAATCAACTTCATTGGGCTGCAGT AAACTAGTGGAAATTAGAGAGTTGTTTTATTGGTGTTTTCTACTGTGAGTTAATTAAAAA TTGTTTTTATTTGGGGTCATTATGTCACAGTCTTGAGTTAACAAGATCTTACGTGATTGG CCTTTTCTTTGTTTTCTCTTAGGAGTTGTGTCTCATGAATGACAGTACTAAAGCTATTAA CAACTAAGAGTTTGACAGAGAACTATAAGCCTGTTGTATCTCCTAAAAGTTGTCAACTCC CCACCCTTGGACTTTAAATGAAAATTTTATTCAGTCCAGCTATTCTTACAGTCCCTAAGG ATTTTCATATATCTATGTATAGGAGATAAAATTTGCTAGTAAGATTTTTAAAAACTGGCT AGTGAAAGGAAAGTACCTCTGAAAGAAACCATTTTAGCAAATTATGGTTATATGTTTTAA TTTAATCTACAGAATGTTTTATAGTAAAATTCTAGCACCACTAGAATAATCACATAGCAT GTACAATATATTTATGCTGGCTGAAAAGACAGAATCTGGGAATAATAAAATTGCAACCAG TTTGGTAATGCAAACAGCAGAATAGAATGAAATCTCAGTAATGAATTAAAGCAACAAAAA GATATTGATTGGCAAAAAGCAAGATATAAGAGATTCATTTGCTTAACATTTCTACATAAT ATTTATGGTCTGGTCAGTATTGGTCTGGTCAGTATTGCCTGGCTGACGTGAAATGTAAAC TAGTAGGCGTGTTATTGATCTGCTAAAACTAACCCTCTTTTTAAGAGGAGATTTAAGGAA GACGTCAATCAAAATGTCAAATATGTGTGTCAGAATATAAATAATTTTTCACATTGTATT GTTGCTATATAAAAAAAATAATAGAATTGGTTGGGTTTCTGAGGTGAAATCCAGAGTAAG AGTACTAGACAGTTCAACAAGCCACATCTAATGGCACAGATAGAGGATGTAGCTATTTTA TACCTTTCATAACATTTGAGAGTAAGATATCCTTCAGGATGTGAAGTGATTATTAAGTAC TCATACCTGAAATCTGTTGTCAAGATTAGAACTGGGGTTCATGTTAAAAACCTTCCATAT TACCTGAGGGTACCTGTGGGGAACAGTTCCTTCCCCTGTGTGGTAGTATTTTGTTGGAAG AGAATGTTTATACAAAAAATGAAATTCTTCCAACAGCAGAGAAACTCTAAAAAGTTTGAT AGTACCTATCAAAGTGCTGTACTTCTGTGATAGAGAACATCTGATGTACCAATTTAGATC TATTTCTTTATACTTTTTCTAATCAATTGCTTAATAGTACTTTGGATGATTATCACCTTT GCCACTTAAAATATATAAATATCCTTTTTACTTCATGAGGAAGGAAGAATTTTTTGATAA TTACTGAGTTCAGCCTTTTGTGATGACTTATATTTTGGACTTACATTTTAACTTTAAAGA ATGTCAGATCCCTTCTTTGTCTTACTAGTTAAATCCTCACCTAATCTCTTGGGTATGAAT ATAAATGTGTGTCATCGTTATATTGTTCAGCTAGATGAGCAAGTATCTTAGGGTAGTAGG TAGCCTGGTGGTTTTAGAAGTGTTTGGTGATTTTTATGGAGAGAGTTTTCCTAAGTGGTG GTTTATAGGTGGTATCAGATATTATTAGGGCAGCTTTTTGGGGAGTAATCTCAGGTCTCC CAGAGCAGCAGCATTTTTCTCATTGATATAAGTAAGATTCTTAGGAGCTTTTCTTATCAC ACAAGATGCCTGAATCGAATGTGAGAATTGAAGGCATTTCTTCTGCATAAACAAAGAATT CTACCTGCTGGACAGAAACCTGGAAAGTTCTTTGGAATTCGCTGAATTACAGTTTAGTAT GTCCTGATTACAGAGTGACAATATTTATCAAGCCTTTGTTATATTGGATTATCTTCTCTC TTAAAATACAACTGTATTATAATTGAAATGACAGCCCAAAATTGGATGGTTTACCAAAAC CAATGAAAGGGATTTCACACATCAATTTTTATTTCTGTTTTGAAGAGCACATGCTATATA ATAATTGCTAGTAGCAACTGCAGTAAAACAGGTGATAAGTTATTTTCTCTGAAAAGATCC AGTCCTAGAGCAGGATTCTTCGATCATTCATGGCAGAGTGAAAAAGGTTTGTATGGTTCT TGTCCAAATAACTCAGTTCTTAAAATTCTTAAAATGATCGTAAACCATTATCCTTTAAAG GTTTATTTGAAGATGCTGTTAAAGTACAGAATTTTGTGTACAGGTAGATTTTTCCGTCCC TCATTAATAGTGCCTTCTTAATTAATACAGACTGGTGTTAGCTATAACAAAACTCCAGTA AGGCCAAAGAATCCCAAGTTCTTTGTGGAAAAAAAAAAAAAATCTTTTAGGGTCAGATTT TCCCTTCTAATATCATTGAAGATGATGTTGCATTGATTTATTCATAAAGTATTTTAACTA TAGGAACTCTAGAAGATAATGGTTAGGCAAGTGATTTTTTTTTTAAATATGGTTGGCGTA AGTTGTATTTTGAAATTCACTTATTTTAAAATCGAAGAGGATTGTAATCATGGAAATAGA ATGTTTGTATCTACCTGCCCACATTTTCTTAAAAAGATATTTCATATACAGATAATGAAG ACCAAGCTAGTGGCTGCACTGTAGGTCTGCTGCTTATTTGTATTTGTTGTGCTTCTGTTT ATGTTGTAGAAGCTGAAATTCTAGCAACATGCTTCAATTCTGTTATTTTGATACTTATGA AAATGTATTAGGTTTTACTATATTGTGCTTTTGAAAGCCATAACTCTTAAGAACTTTGTT TTTGCATATTGTTTGCTAATTCTTTACTTTAATAAACCTCAAAACCTGCTTAATGTGTCT TTTTTTGTTTTGGCTCTGGAGTTGGCCTGCCTGCGTTTGAGTCATGGGCCTCATAGCTTA GACAAGTTGCTTAACCACTCTATGCCTCACTTTCCTGACCTGTAAAGGAAAAGTCTACTT CATAGGAAGGATTTGAGGGAAGATTAATTGAAGTGTAATACAAATACAGTATTTAGAACA GTACTTAGAACATAAGAACTCAAATATTAAAATTGTTACTATCTTTTACATTTCCACTAG TTCTTTGATTCAGAATAATTACTTCTTATGTTGCTTGACCTCGGTGTATCAACCTTTGAT GATCCACTTTGTGAATTTACAATTTTTTATTTCCTTTTGTCTTCTTTTTTGAAAAAATTT TAAATCACAGACTGACTTTGCATCATTGTCACTGTGTTGCACACTTTTACCAACCTCTGA ATTACATATACAAGACATGCAAACTCATTCTAATTAGAAAGGAATGGTGAGCGAGGCACA GTGGCTCAGGCCTGTAATCCCAGCTTTTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGT CAGGAATTCAAGAGAAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATCCAAA AATTAGCCGGGTGTGGTGGCGCGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAAGACAG GAGAATCGCTCGAACCCAGGAGGTGGAGGTTGCACTGAGCCAAGATCATGCCATTGTACT GCAGCCTGGGCAACAAGCGATACTGCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGGAAT GGTGAAAAATCATGTGCCCTTGCCAGAAATGTAGAAAAACCCAAACTACATATTAACCCT AAAGGATAAAGATAAAAGCACTTGTTCTTTTTTTTTTTTTTTTTTTTTTTAATAGATAAA AAAGACTCTATTCAAGCTTGTCCAGCCTGCACACATGGGCTGCATGTGGTCCAGGACAGC TTTGAATACGGCCCAACACAAATTGGTAAATTTTCTTAAAGCATTATGAGATTGTTTTGC GAGTTTTTTTTCTTTTTTTTAGCTCATCAGCTATCGTTAGTGTTAGTGTGTTTTATGTGT GGCCCAAGATAATTATACTTCACTGTGGCCTAGGGAAGCCAAAAGATTGGACATTCCTAC CAATTTCTGAGAATCAGTTCCTTCCTATGTCTTTTTACTTAAAAGGCATTTTGTAAGGTA TTTTGTAGCAACATCACTGGTTGTTTTAGAAGTGTATTTTTTAAAAAAGCACACTTGTCC TAGCGGAAGAAGGTTCAGTGAGCACTAAGAGGATGTTGGCTTCTCTTGGGTTTAAGATAA TTAGTTTTCAGGTTGCTGTAGCCAAAACAGTTCAGGTGATGAGGGGTTGGGACAGTGGCT AATACTATTTTGTATTACAGCAGTTTTGATGCAGCTATCGTTTTATAAACATTTTTAAGA TTGTCAGTAGACTGCAGCAATGCTTATAAGGAAGATTTATTTAGAGCTCTGTAGTATTTA TGATTGAAAGAAGGAAGCATTTTTAAAACACCCTTCCCATTTAACATTTTAAATATTACT GATTTTTGTCATTGAGTTTGTAAGTCTATCATAAGCTTTGCAAAAACAAAACTTGTTCTT TCTATCTAAATCAGTTTTTCTGTTTAAAAAAAGGGTAATGGGGCTATAGGGAAAATTCAA AGAAGAGCTATGGGCAGCTTGCTTAACCATCTCCATGTTAACGTATGTTGGATGGGAGGT GGGAAGAGGGATTTAGACTGGTGGTGAAGACTTATCCATATTATATCAAATGGGTGTGTG TATAATTCCTAGTGAGAGATTTTCTGAGGCAGTTTATTGATGTTTAGAGATGGATTTTGA AAAGATCCTTATACTTTGTCTTAATCAGTTACCCCTTCCCATCTAATAAACCTCCTTCAT TATTTCATTTTAAATAATACTTTCATTTGAGATAAATGCTGAGAATTTTAACAGAAAAGT TAAAACTGAAACCCCCAAACCAGTAGCAAAGGTTTATGAGTGTGCCCTTCTAACCTGTTC TGGTAGTCACTGTACATTGATCCTTGGCTTTCTTTGACAGATACTTTGCTGATTATAGAT GGAGCTCTAGCTCTTTTTGAAAGGGTTCTCAGAGAAATTGGTTTGGTTCTAAAGTGTTTC TTGAGTTCTTTGTACCTAAGAAAGCCTTTCATTCTGCATAGCGTTTATCACCATCCAACA TATATATTTCTTTACCCTGTTTATTGACTGTCTTACCTCATGGGAATGTAAGATCTGTGA GGACAGACCTGTGTTGCCACTGCTAGAACAGTTCTTGATATGTTATAAGTAAGCATACCA ATATTTGTTGAATGAATGAGAGTACTGAAGCAAGAAGTGAATTTTTTAAGTATTAGAATT TACCTTTTAAATAATGTAATATTTACTTCTTAGTTGAATTGCTTCTAGCTCAATGTTTTA TTAGCTCTCTTTATGCCTGAGAAGTGGTTTGATGTGGGGTGGGGTATTGTGGGAGCTGGC TAAAGTATAATTGAGAAGAAGGGGAAATTCAGCTAAGAAAGCACTCATATCCTTTCTCTT TGAACTTTTGGACTTTTGCTCCAAAGTTATCAAATTCTTGGAATTGTTGCTTGTAGAACC TGCAAAATTAATAGTCAAGTTAGAGCTTTAACCTGTTAACATTTAATATTTTCCCAAAGA AAGTAGGAAGGGCATAGTTTCCTTGATACGCTTGACAAGAGAAAATAACCCCAAAAAGTG TACTTTTAATTACACAGCTTACAGAAGCTGGGGTGTTACAAATTTTGTAGTGTGATTTTA GTGCCCTGGTTTAGACCCCATAATATCCTTCCCTAACTGTTGTACATAAGGGGCAAGCCT TTCATTGCACTCAGGTGGGAGTGGGAGCAAGGAATACCTTTGAGAGAGAGAACGTATGAT AAAACAAATACATGAACCATATTTGTGCTTCAGAATAAAAGATTAATTTTGCTGAAGAGT GTGTGTGGGTGATGTAGGGGGAGAAGTTCAGGAAGAAGAAACAACAGGGTCTAGAGGGTT TTTTAGATTTTGTCCACTTTATAGTTTTGCCAACATTAGTTCAGAAGTGTAATTAACAGT AAACTTTCCCTAATTGCCTTTTGTTTACATAAAATTTTGTGAAATGTGGTTTTCATTAAC TTAGAATTGTTTAGACCAAGTTAGTGAATTCAGTGAAGGTGAAGAATGCAGGCACAAACT AGTAATGTGTAACTAGTAAGGCTGGAGAGATGATGTTCATATGAAAAGAAGGTCCTTTCC TTTTATTGTCTGTTTAATAACCTGCTGTAAGCTTACCAATGCCCATTTGCCCTTTCATTG CAGAACACCTGTGTCCAGCTGGATACCACGTTTCCTAGCTTTTTTTCAGCTAGGTATGGT CATGTGACTAAGCTTGGCCAGTAGGATATTAGCAGAAGTGATAGGCACCACTTCTGCATT ATATCTGGAAGAGGAATGCACCCCTTGCTCTTTTCCCCTTCTCAGTGGCTGGAATGCAGA TATGAAGGCAGGATCTAGCATAGATACCTTGAAGTGGACATGGAAGCCGAGGGATGAGGA TGACAGTTGTGCTACCCCTGAAAGAGTACTGTGCTACACCTGAAAGAGTACTGTGAGAAA GAAACTTGCGTGGCGGATGGCTTTGTTATAGCAGTTTGGACTGTAACCTAATTAATACTT ACTTGCCAATTGAGTGATTAACACAGGTCCAACTTTATGGTAGGCAGGGCAGTAGGGCTG GAATCATTGTTCTTGTCCTCATGGAAAGTGAAGCTGTAACAGAGTAGTTCCGAGTTCATT AGGTTAATCAGTTTTGGAGGGTGGAGAAGCAGGACCCACAAATGAGGGTTATTTTAAACT ATAGACTCTACTTCTGTGTTTCTGAATATTTTTATTTTTTCTGGCCCTGAGCCGTATGAG CTTGTTCATTCATTTGACTAATATTTGAGGGCTTGTTAGATGTCAGGCTGAGGAATAAGA GTGGTTAAAACAAAAATTCTTTCCCTTAAGGATCTTCATTCTGGTTAATGAAGACAGCAA ACAAGGTAAATAAAATATATGGTGTGTTTACTAGTAAGTTCCAAAGAGAAAAAAATAAAG CAGGAAAGGAATATACCAGGGTTGGGGAACAAGGTGGAATTATAATTTTAGATATAGTAG CCAGGGAAGGTTTCACTGAGTAAATAATCTTTGATCGAAGTCCAGGAAGATGAGGAAGTT GTTACGTGAAGCAGTGATTTAACCAGTTCTTATTCAAGGCAATTCAGAAGGCATGTGAAT GTTACTGCAATGATCTGTGCTTTTCTGCAGAAAATGAATAATTCAAGCAGAAATAGCTAA AGGTACAAACTTCTATTAAATTGCTTGTTCTTTAGTCTCTGCAGGAGATATAGTAATAAC TGAAGTGTTACACAGGTGGAGACGGGAAACGTTAGTTGCTAAGAACTTTGGATTACCACC GCTAGGAAACCAGCCACTTGGAAGACCAATCAATAAAGGAGTGTTCAACTCAATATTTCA CCTGATACAAGGTTAGTTTAAGGTGGAAAATCAAAGGATATGTGCTCCGATGTAAATACA CCTTTTAAATTTACTTTAGCTCTGTTTTCCCTCTGTATTTCATTCAATAAATATTTATTG CCTATTTTCTGTTTAAAACTATGCTAGGCATTGGGAAACAGCAGTGAACAGGACACATGT TGTCCCTGTTCTCTGTTCATACAACTTACATGTTACTAGTGGGAAGAAGCATTGGGCTAC TAATTATGCAGTTATTTAGTAGCTGTGATTGGGGAGGCAATATGGGGTCATGAGAGGATT AATCTTACCTGAGGATTTAGGCAAGTCCTTTTTGAGGAAGAAACATTTAACTGGAGACCT GAAGGATGAGAAGGCATCAGCCAGAGGAAGGAGGAGAAACAAACAGCTTAGGCAGAGGTA GGGATTGAAAGGCCACTGGAGTGTAAGAGGAGTGAGAGAAGATGAGGCTGGTGGGACCAG TTGATTCTGGTCCTTATTAGGCTTTTGTGTTTAATCCTGAGAGCAAAGAGAAGCCATTGG TGTATATGCTGGGGCTGGCGGCAGATGTGTTTATTGAGTGAGGAGAGACAAAAATGGAAG TAGGGCTTTGAGTTAGGGTTGTGATGGTGGACATAGACAGGAGTAGATGGAGTAGAGTGG TGCCTAGGGGGTGATGAGTTACATATTGAAGGATGAGGAAGAGTTTAGGGTCAAGAATGA CCACCATGCATTTTTTACTTTGGGCAGCCATACGCTGGTGCAGTCTATTCAGATGAAGAC TGAAGGAGGATCTAATTTAGACAGATGAGTTTTAGGCTTGTTGAGTTCGAAGTTTCCCAT GAGATACCCAAATGGAGGTGTTGAGTGGGCTCAGGGATAGTGTGGAGAGAGTCATCTGAA AAGCAACTGAAGCCATGAGAGCGAATGAGATAGTTTAGGGGGAAGGTGCAAAGTGAGAAA AGACCCAGAATAGCTGTCCTCCAACTCTGGGCATACCTGTTGGGAAGTACAGACCTCTTT ACTGTTTCCTGATAGCACATGGCTGAAAAAGGACAGGTCACTGACAAAAAGTAGTTTGTA CCACTGCATGCACTTCTGAAATGGCCATCCTGGTTAATAATGATAGCTCACATTCAGGGC ATTTACTACATAGCAAACATGAGCTGAACACTTTACTGATAATGTTTCACTCCATATTGA AAATCCTTTGAAGAAGGTATTGTCATCTCTATTCTACAGATGATGAAACGGGCTATCAGA AATACAGAAATAACGATGAAGGCATGGAGTGGATGATCAAGCTCAGGTCATTGGCTCCAG AACTCAGACTCTTGGTCACCACTATGCTACCTCTCCTTGACTCCTAGCATCTGCAGCTAC CTCCCCACCGTGATCTCCAGCCTCTCCCCCAACCCCCACCAACAAAAATGCGTTAACCTC AACCCTTCTGGCTGCTCACTGT bcftools-1.21/test/csq/ENST00000545279/ENST00000545279.fa.fai000066400000000000000000000000211467060157400215500ustar00rootroot000000000000005 55942 25 60 61 bcftools-1.21/test/csq/ENST00000545279/ENST00000545279.gff000066400000000000000000000061201467060157400211740ustar00rootroot000000000000005 ensembl_havana gene 21 55922 . + . ID=gene:ENSG00000113658;Name=SMAD5;biotype=protein_coding;description=SMAD family member 5 [Source:HGNC Symbol%3BAcc:6771];gene_id=ENSG00000113658;logic_name=ensembl_havana_gene;version=12 5 ensembl_havana transcript 23 49909 . + . ID=transcript:ENST00000545279;Parent=gene:ENSG00000113658;Name=SMAD5-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000545279;version=1 5 ensembl exon 23 138 . + . Parent=transcript:ENST00000545279;Name=ENSE00001231815;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001231815;rank=1;version=5 5 ensembl five_prime_UTR 23 138 . + . Parent=transcript:ENST00000545279 5 ensembl exon 15008 15082 . + . Parent=transcript:ENST00000545279;Name=ENSE00001375348;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001375348;rank=2;version=1 5 ensembl five_prime_UTR 15008 15082 . + . Parent=transcript:ENST00000545279 5 ensembl five_prime_UTR 20768 20936 . + . Parent=transcript:ENST00000545279 5 ensembl exon 20768 21339 . + . Parent=transcript:ENST00000545279;Name=ENSE00003607923;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003607923;rank=3;version=1 5 ensembl CDS 20937 21339 . + 0 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl exon 28032 28283 . + . Parent=transcript:ENST00000545279;Name=ENSE00003658167;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003658167;rank=4;version=1 5 ensembl CDS 28032 28283 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl exon 30448 30567 . + . Parent=transcript:ENST00000545279;Name=ENSE00003585794;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003585794;rank=5;version=1 5 ensembl CDS 30448 30567 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl exon 39610 39831 . + . Parent=transcript:ENST00000545279;Name=ENSE00003542635;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003542635;rank=6;version=1 5 ensembl CDS 39610 39831 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl exon 41552 41808 . + . Parent=transcript:ENST00000545279;Name=ENSE00003558908;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003558908;rank=7;version=1 5 ensembl CDS 41552 41808 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl exon 44513 44572 . + . Parent=transcript:ENST00000545279;Name=ENSE00002232122;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002232122;rank=8;version=1 5 ensembl CDS 44513 44572 . + 0 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl CDS 44575 44655 . + 0 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 5 ensembl exon 44575 49909 . + . Parent=transcript:ENST00000545279;Name=ENSE00002251256;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002251256;rank=9;version=1 5 ensembl three_prime_UTR 44656 49909 . + . Parent=transcript:ENST00000545279 bcftools-1.21/test/csq/ENST00000545279/splice-region-insert.txt000066400000000000000000000002271467060157400234640ustar00rootroot0000000000000044572 T TC splice_donor&splice_region|SMAD5|ENST00000545279|protein_coding 44572 T TC splice_donor&splice_region|SMAD5|ENST00000545279|protein_coding bcftools-1.21/test/csq/ENST00000545279/splice-region-insert.vcf000066400000000000000000000010201467060157400234130ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 5 44572 . T TC . . EXP=splice_donor&splice_region|SMAD5|ENST00000545279|protein_coding;type=ENST00000545279:135513085-T-TC, ambiguous case, curious 2bp intron with non-canonical AT..AT splicing, could also be a frameshift bcftools-1.21/test/csq/ENST00000557788/000077500000000000000000000000001467060157400166705ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000557788/ENST00000557788.fa000066400000000000000000000012401467060157400210360ustar00rootroot00000000000000>15 15:22472818-22473453 CCGCGCCCCCTGCTGGTCCTGAGCAGCACCTGCGTCCGCGCCCTCCGCCTCCTGGCAGGG AGGTTTGTGTCTGGGCTCACACTCACCTCCCCTCACTGTGTCTCTCGCACAGTAATACAC GGCCCTGTCCGCGGCGGTCACAGAGCTCAGCTTCAGGGAGAACTGGTTCTTGGACTTGTC TACTGATATGGTGACTCGACTCTTGAGGGACGGGTTGTAGTTGGGGCTCCCACTATGATA GATTTCCCCAATCCACTCCAGCCCCTTCCCTGGGGGCTGGCGGACCCAGCTCCACCAGTT ACTACTGCTGATGGAGCCACCAGAGACAACGCAGGTGAGGGACAGGGTCTCCGAAGGCTT CACCAGTCCTGGGCCCGACTCCTGCAGCTGCACCTGGGACAGGACCCCTGTGAACAGAGA GACCCACAGTGAGCCCTGGGATCAGAGGCAGCCTCCCCTATCTTCATGTCTGGATCCCTG AGATACTCACATCTGGGAGCTGCCACCAGGAGGAGAAAGAACCACAGGTGTTTCATGTTC TTGTGCAGGAGGTCCATGAGTCTCAGAAAGTATTTCCCATGTGAGCTGGACCCTGAATTT AAGGAAATGTGTGGTGGTTTCCTGTGGGTGCCTAAG bcftools-1.21/test/csq/ENST00000557788/ENST00000557788.fa.fai000066400000000000000000000000201467060157400215670ustar00rootroot0000000000000015 636 25 60 61 bcftools-1.21/test/csq/ENST00000557788/ENST00000557788.gff000066400000000000000000000020451467060157400212160ustar00rootroot0000000000000015 havana gene 101 536 . - . ID=gene:ENSG00000259261;Name=IGHV4OR15-8;biotype=IG_V_gene;description=immunoglobulin heavy variable 4/OR15-8 (non-functional) [Source:HGNC Symbol%3BAcc:5658];gene_id=ENSG00000259261;logic_name=havana_ig_gene;version=2 15 havana transcript 101 536 . - . ID=transcript:ENST00000557788;Parent=gene:ENSG00000259261;Name=IGHV4OR15-8-001;biotype=IG_V_gene;havana_transcript=OTTHUMT00000415968;havana_version=2;tag=basic;transcript_id=ENST00000557788;version=2 15 havana exon 101 407 . - . Parent=transcript:ENST00000557788;Name=ENSE00002563019;constitutive=1;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002563019;rank=2;version=2 15 havana CDS 101 407 . - 2 ID=CDS:ENSP00000473987;Parent=transcript:ENST00000557788;protein_id=ENSP00000473987 15 havana exon 491 536 . - . Parent=transcript:ENST00000557788;Name=ENSE00002569579;constitutive=1;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00002569579;rank=1;version=2 15 havana CDS 491 536 . - 0 ID=CDS:ENSP00000473987;Parent=transcript:ENST00000557788;protein_id=ENSP00000473987 bcftools-1.21/test/csq/ENST00000557788/ascii-art.txt000066400000000000000000000003241467060157400213040ustar00rootroot00000000000000 90 101 eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee.... CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGTCCGCGGCGGTCACAGAGCTCA.... C--------------------------------------CCGCGGCGGTCACAGAGCTCA.... bcftools-1.21/test/csq/ENST00000557788/long-overlap-del.txt000066400000000000000000000002751467060157400226040ustar00rootroot0000000000000090 CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT C coding_sequence|IGHV4OR15-8|ENST00000557788|IG_V 90 CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT C coding_sequence|IGHV4OR15-8|ENST00000557788|IG_V bcftools-1.21/test/csq/ENST00000557788/long-overlap-del.vcf000066400000000000000000000007461467060157400225460ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 15 90 . CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT C . . EXP=coding_sequence|IGHV4OR15-8|ENST00000557788|IG_V;type=ENST00000557788:22472907-CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT-C bcftools-1.21/test/csq/ENST00000571540/000077500000000000000000000000001467060157400166465ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000571540/ENST00000571540.fa000066400000000000000000000150721467060157400210020ustar00rootroot00000000000000>17 CAGCCCCAGTTCACCCCTCGGGGCGGAGGATCTCCTGAGTGATTCATCAGAACCCCCTGGGCTCAACCAAGTGTCGTCTG AAGTGACCTCCCAGCTCTATGCTTCTTTGCGCCTCAGCCGGCAGGCGGAGGCCACGGCCCGAGCCCAGCTGTATTTACCC TCCACCTCCCCGCCTCATGAAGGGTTAGACGGCTTCGCCCAAGAATTGAGTCGAAGCTTGTCAGTCGGATTGGAAAAGAA CTTGAAGAAAAAGGTGAGGGAAGTGTGTCTTGGAGACCACTGTGGCACTAGACACCAGAGAGTCTTGGGATTGGGGTTGG TAAAAATAAAAAGCTTTGATGAGATTTGAACTCTTCCTGTTGGATTTCATATTCCTTTTAACTGCATAGGCAGCCATGCT TATAAGGGAGGGAGTGACCTGGGACACCATAATTTGAAAATTATGAAACTTCCCAGTGTTTTTTTGTGAGAGACATCTCT GCTCCGAGTAGATAGAGCAAACCTATGGGGTAGGTTGGTGAGCTATTTCCCGTGCACTGGGAATGGGTAAGGTTTCTTGA TCCCAAGAGGGAGCTAGGGACTTAGGATAGCAGCTCCGATCCTTCCAGCTCAACACTATGTTGATAGTATGGTTCCAACT TTGGCATGTACATCATTAAGACATAGCTTAGTCAACTACAACATGTTACAGAGAAGATAGTTATTAGTATTGTATAGAAA AGGTGTCAGAGTCAATTTGCAGACTGGTTAGGTCTTCCAGAGTTTGAAAATGATAGCCATAAGCCATACAGTCCTTACAT TTGTTCTTGAATCGGCAAGAATCTCCGCAACTCTTGTCTTATACCTCCTCGATTATTTTATTTACACTCTCTTTCTGGCT TCTGTAGTATTTGAATTTCTGATTCAAGTTTAGGACATCCCTTATTGGATCCGTTTGGTTTTTCTTGTTTTCCAAAGTGC TGGAGTGAAAATTCTACCCTGGCAATAGGTAGGAGATAGATAACACAGACTGCATCTGATTTCCATGTGGCTTTTTTCCA GGATGGTTCTAAGCATATCTTTGAGATGGAAAGTGTTCGGGGTCAGCTCCAGACCATGCTCCAAACCTCACGTGATACAG CCTATCGTGAGTAAGCCCCTTCCCTAGAACTATGAAGGAGAACCTAGATGTAAGGGGTGGGAGAAAGTGGACAGAGGAAG CAGGCAGGAAAACCTCTGAGCAAGAGATTTCAGGAGAAAAGTCTCCCGTTCTTTGGGAGAGGGGGTGAAGGAGTGAGGGA ACTGGAAAGGAAGGCCTTTTCTCTTCAGGTGGCCCCTGTTTTTGTCATTACCTGACTCTGGCTTTGGGGTCCCTCTGGCT GCCTGCAGGGGATCCTCTCATTCCTGGCGCTGGCTCAGAGAGACGGGAAGAGGACTCCTTTGACAGTGATAGCACAGCCA CCTTGCTCAAGTGAGTTCTCCTTGTGGTTCTCCTAGCTTGTTTGCTTTCTTGGAAATCCAGGTGTTTTGTTCCTTATTTC TCCCTTTATTGCTTTTGTACCTCTTAAGAACCCAAGAGGCTTATCACTTGCCTTTCAGTTTTCATCTTTTTCTACTGTCT CCTGCCCCCTTTACTCCTTCAGGAACACAGGTATCTGTTGCCTAGTACCTGGCTTTCTCTTAACCTGCAGTCATTCTTCC CCTCTAAAGAGTTAGCTTGTTTCTGCTGAAACCTTTAAGTGAATCACAGACCTGTGTGTTATTTATAGCACTATGGTTAT ATAGCTTTACGACTTTGGACAAGTCTCTTGCCCTCTCTGGGTCTCAGTTTCCTCATTTGTAGAATATCACAGTTGGACAA GTGGATTCCAAAAGCTTTCCCAGCCCTAACATTCTCTACCTGATTTGCTCAGCACCCGGCCCCTGCAAGACTTGTCTCCA TCTAGCTCAGCCCAAGCCCTGGAGGAGCTGTTTCCCCGCTACACCAGCCTTCGGCCAGGGCCTCCACTCAATCCCCCAGA TTTTCAGGGGCTGAGAGATGCATTGGATTCAGAGCATACCCGCCGCAAGGTAAGATGCAAACGCTTCCTTTCGAAAGCAG CAAAGATTAGAAAGAGGGGACCCAAGTGTTGAAAAGGGCTGAGGGGGCCTGGCGTGGTGGCTCACGCCTGTAATCACAGC ACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCGTCTCTA CTAAAAATAGAAAAAATTAGCCGGGCATGGTGGTGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATG GCGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATCATGCCGCTGCACTCCAGCCTGGGCGACAGAGCGAGACTCC GTCTCAAAAAAAAAAAACTAAAAAAGAAAAGGGCTGAGGGTTAAGAGCCTGAAAGCTGGGACTTAAATGTTTTTCTGAGG AGGGCTTTTTTGACCATTCCATCTAATATGGCACCACCTCCTTTCCAAGTAGTCAGATCGCCTTCTTATTTCTTTCATGT AGCTTATCGTTCTGATATATCTTGTTTTTTTCTCCTCTCTAAAATTTGAGGGTCCGTATCTTGTTTGTCTTAGTACTGGC TGCCTAAGGTCTAGAATATACATAACACAGAAACACTCTGTGTTTGTCGAATGGACACAAACTCTGCTAGCTTGTGCACA GGATTTACAGCTACTGGTGATATACTGAGCTTTATCTCTGTGAGCCTCTGCCTTAGTGTCTGAAGGGGACAGAGAAATAG ACAAAGGAGAGGAAAAGTCAAAATCACTGGTTGCCATTTTTGGAAGCCTCTCTTTCTCCATGTTAAACCCCTTGGCATGA ATGAAAGGCTTTCCCCTTTATCCTTGCTGTGTTTATTCATTGTGTCCAATGAGCTTCTGAAGGTAGGAGTAACTTTGCAC ATTTTGCTGTGTGGGCTGCTGCATCTCTGCCAAAAGGTTTATGGGATTTTTACTCAGGAGATCCAGGAAAAGGAGGAGCC TGGAATCTAAGCACTTATCTCCTGAAAAGGTACAGAAACATGTTGGAGATCTTGAGCCTCAAGGTGCTTGCTTCAGAATT TTCCTGATTCTCCCTCTCCAGACCTATTCTGTTCTTGGGACCCAAGCTTCTTGGCTCCAGCCCACTCCCCCACTAGAGGA GCTGGAAAGTTTGGTGCTGTGGTCATACCAAAGATGGGCAACACCCAGACTCCTCACCCTTTTCCCCAGCATTGTGAGCG CCATATTCAGAGCCTGCAGACCCGAGTGTTAGAGCTACAGCAACAATTAGCCGTGGCTGTGGCTGCCGACCGCAAGAAAG ATACCATGATTGAACAACTGGACAAGGTACCAGGGTAGCAAAATGTGGGTGGGTCTCTCCATGAAGAGCATTAAGGAATA ATAAATAAGTGGGTGGCCAACCAATGTTTCTTGGTACATGCTGAGAGCTGGGCAAGGGGTTGGTTTGCTGACTGTTGGGA GAAGATGGCTGTTGACCCTGCCCCTGTGGGTAGAAAGAGGCAAAAAAGTTATTTTGAAATTTCATCTTACTTGCCCTACC TAAGACCCTGGCCCGTGTGGTGGAGGGCTGGAACCGGCATGAGGCTGAGCGGACAGAGGTTCTCAGGGGACTTCAAGAGG AACACCAGGCAGCAGAGCTCACCAGAAGCAAGCAGCAGGAGGTGAGCGCCCTGGAGCATATGGCATTAGAACCTGAGTCA CAGATCTCAAGATGGAAAGGGGCAGAAATAGCTCTGGAATTAGGGTTTCCAACAGATTGACCTCAGTCTTGTAGTGGCTG TCCTGACATTTCTTCTCATCCCTCCTTTCTTCTCCTTTAACCGTTTCTGCTGTCCAACTTGAATCATCAATGTCTTAATT TTTCCCACACCATGTAGTCTTCTATCTGGCCCCTTAGTCATTTAGTTAACTGTGAAGTTTCAAGTTTACATTGTCAATGC TTTATAAAATATAGCACACACAGATTTCCCACAGTTCCTCTGCCCTGTATTCCTCTCTTCCTGAAAGACAGTAACCCGCC TGGAACAAAGCCTTTCTGAGGCCATGGAGGCCCTGAATCGTGAGCAGGAAAGTGCCAGACTGCAGCAACGGGAAAGAGAG ACACTGGTGAGAAGATTGGACTGGGTTAATTCCACTGGAAGCTGTTAATTACTTCTAGAGAGCTGTGGGCTATTGGTGGA TTGTGGGAGATTATAATTTGAGTTGCACCAGAGCACTGTTTCCCAAAGTGTGTTCCTTAGAACACTAATTCAGCTAGATA TTCTATTAAAAAAAAAGGCTCTGCTACCAAGTCGGTTTGAGAAACTCTGCAAATTGTATCATCATTAGAATATTAGTGTC ATCTGAAGAATTATTTTAAAATATAGGCTAGGCACGGTGGCTCACCCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAG GCAGATCATGAGGTCAGGAGTTTGAGACCAGCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAACTA GCTGGACATGGTGGTGCATGCCTGTAGTCCCAGCGACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGCAGGCAG AGGTTGCAGTGAGCTGAGATCAAGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAATAAAAATA AAAAATAAAATAAAATAAAGATTTCTGGGACTCACCTGCAGAGGTTTTGATTCAGTAGATATATGGTGGAACTCAAATCT TTTCAGAAATTTCCTGGGTGATTTTTTTCAATCTGGTTTGGGACCTCTGGTGTAGGGCATGGCCAAAAAAGGTATGAAAT TGACTAACTCAAGTTTCTTTTCGTGTTTTTTTTTTTTTTTTTTTGAGACAGGGTCGCGCTCTGTTGTCCAGGCTGGAGTG CAGTGGCACAATCTCAGCTCACTGCAGCCTCTGCCCCCTGGATTCTAGCGATTCTCCCACCTTAGCCTCCCAAGTAGCTG GGACTACAGGCGTATACCACCACGCCTAGCTAATTTTTGTATTTTTTTGGTAGAGACGGGGTTTCGCCATGTTGGCCAGG CTGGTCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATAAGCCACCAT ACCCAGCCACTTCACTCAAGTCTCTTAGAGCTGAAATGATAAGGTGATTAGCCATATGAATTAGTAGCTGGGATTGGAAC TTGTTGCATGCATAATGCATGCTTGCTACATGCATGCTGGTACTTGTAGTCTTAACAGGCTATATCTGACAGTCCTGATG ATGATGGGTGATGGTTCACGATTATAGGCTGGATATTCTAGTCTTAGTGGAATTTCTTTTGACGATGATGGTGGTAACTA TTGTGTATTGAGTACTTACTATGTGCCTGATGCCGTGCTAAATGCCTTACATATGCTTTTTACTTTAATGCTCAGAAGGC AGACCCTGTTATGATCTCCAGTTTACAGATAAGAATGTATGCCTAAGAACACATAGTAAATTCCAGAACCAGGATTCGAA CCTGAGATTTGAACCCAGGTCTACCTGGCTCTGGAACAGGAACTCTTATCTACTATATTATAATCCTATGAGCTTGTCAA CTATTGTGTTTGTTTGTTTTGAGATGGAGTCTCGCTCTGTTGCCCAGGCTAGGGTTCAGTGGCACAATCTTGGCTCACTG CAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAATACAGGTGTGCACCACCATG CCCAGCTAATTTTTATATTTTTAGTAGAGACATGGTTTCACCATGTTGGCCAGGCTGGTCCCAAACTCCTGACCTCAGAT GATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCGCCTGTCAACTATTGTGGGGTTTCTT TTGGTTTTATTTGAGATGGAGTCTTGCTCGATGTCGCCTAGGCTGGAGTGCAGTTGTGTGATCCCAGCTCACTGCAACCT CCACCTCCCAGGTTAGAGCGATTCTCCTGCCTTTGCCTCCCAAGTAGCTGGAATTACAGGCACCCACCACCACGCCTGGC TAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGACCAGGCTGGTCTCAAACTCCTGACCTCAGGTAATCT GCCTGCCTTGGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACCGCACCCGGCCTAATTATTGTGTTTTTAATGAGC ATAATTCTCAGCAGGCACCTTGTATGAGGGTCAGAGGGCAGATCGCTGGTCTCTGAAGAGCCTACTAAGGAGCTTGGTTT TCTTCTGCGGCTGTAGGAGGAGGAAAGGCAAGCTCTGACTCTGAGGTTGGAGGCAGAACAGCAGCGGTGCTGTGTCCTGC AGGAAGAGCGGGATGCAGCTCGGGCTGGGCAACTGAGTGAGCATCGAGAGTTGGAGACTCTTCGGGCTGCCCTAGAAGAA GAACGGCAGACCTGGGCCCAGCAAGAGCACCAGCTTAAGGAACACTACCAGGCGCTGCAGGAGGAGA bcftools-1.21/test/csq/ENST00000571540/ENST00000571540.fa.fai000066400000000000000000000000201467060157400215230ustar00rootroot0000000000000017 6627 4 80 81 bcftools-1.21/test/csq/ENST00000571540/ENST00000571540.gff000066400000000000000000000046711467060157400211610ustar00rootroot0000000000000017 ensembl_havana gene -995 16824 . + . ID=gene:ENSG00000170037;Name=CNTROB;biotype=protein_coding;description=centrobin%2C centriole duplication and spindle assembly protein [Source:HGNC Symbol%3BAcc:HGNC:29616];gene_id=ENSG00000170037;logic_name=ensembl_havana_gene_homo_sapiens;version=14 17 havana mRNA 21 6607 . + . ID=transcript:ENST00000571540;Parent=gene:ENSG00000170037;Name=CNTROB-206;biotype=nonsense_mediated_decay;transcript_id=ENST00000571540;transcript_support_level=5;version=5 17 havana exon 21 253 . + . Parent=transcript:ENST00000571540;Name=ENSE00002655061;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002655061;rank=1;version=1 17 havana CDS 21 253 . + 2 ID=CDS:ENSP00000458688;Parent=transcript:ENST00000571540;protein_id=ENSP00000458688 17 havana exon 1042 1126 . + . Parent=transcript:ENST00000571540;Name=ENSE00003522521;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003522521;rank=2;version=1 17 havana CDS 1042 1126 . + 0 ID=CDS:ENSP00000458688;Parent=transcript:ENST00000571540;protein_id=ENSP00000458688 17 havana exon 1369 1450 . + . Parent=transcript:ENST00000571540;Name=ENSE00001609771;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001609771;rank=3;version=1 17 havana CDS 1369 1450 . + 2 ID=CDS:ENSP00000458688;Parent=transcript:ENST00000571540;protein_id=ENSP00000458688 17 havana exon 1893 2049 . + . Parent=transcript:ENST00000571540;Name=ENSE00003784956;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003784956;rank=4;version=1 17 havana CDS 1893 2049 . + 1 ID=CDS:ENSP00000458688;Parent=transcript:ENST00000571540;protein_id=ENSP00000458688 17 havana CDS 3142 3312 . + 0 ID=CDS:ENSP00000458688;Parent=transcript:ENST00000571540;protein_id=ENSP00000458688 17 havana exon 3142 3386 . + . Parent=transcript:ENST00000571540;Name=ENSE00002678822;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002678822;rank=5;version=1 17 havana exon 3605 3721 . + . Parent=transcript:ENST00000571540;Name=ENSE00003688389;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003688389;rank=6;version=1 17 havana exon 4068 4166 . + . Parent=transcript:ENST00000571540;Name=ENSE00003562163;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003562163;rank=7;version=1 17 havana exon 6417 6607 . + . Parent=transcript:ENST00000571540;Name=ENSE00002649879;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002649879;rank=8;version=1 bcftools-1.21/test/csq/ENST00000571540/nmd.txt000066400000000000000000000002411467060157400201620ustar00rootroot000000000000003188 C T missense&NMD_transcript|CNTROB|ENST00000571540|NMD|+|201P>201L|3188C>T 3188 C T missense&NMD_transcript|CNTROB|ENST00000571540|NMD|+|201P>201L|3188C>T bcftools-1.21/test/csq/ENST00000571540/nmd.vcf000066400000000000000000000006611467060157400201270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 17 3188 . C T . . type=ENST00000571540:7936284-C-T;EXP=missense&NMD_transcript|CNTROB|ENST00000571540|NMD|+|201P>201L|3188C>T bcftools-1.21/test/csq/ENST00000573035-bt2212/000077500000000000000000000000001467060157400175615ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000573035-bt2212/ENST00000573035-bt2212.fa000066400000000000000000001430041467060157400226250ustar00rootroot00000000000000>7 7:53036-102995 TTAAGTGAAAAGGGAGTGTGGTAAAATTTTCTTTGATTCTAAAGATAAGAATTTGCTGGAGAAAAGAGCA GCACATAATTGCAGAATATTAATAAATGGTTAAAACTTTGCATTGGCTGGGATTATAGTGATTTTTTACC TTCTGCTACCTAGCAAACTTTTGTCTTTTCAAAGACGTAAAGTCTTTACTTAAAATAAATATGCATTGCT GTATTTATAGGGAGGGCAGAGAGGATTTCCCTACACAATCTAGCTGAAAGTTCTCACATGCAATCATATC ATTGCATTTGCTTTTCTAGGCATTTCCCTGGAAATGGCAGCTGTGACAGTAAAGGAAGAATCAGAAGATC CTGATTATTATCAATATAACATTCAAGGTAATTTGAATTAATGCAATTTTTCTTTCTAAAAATTATTCGT GGTTAAAATTAAAATTTGCTCATCAATTGCTTTAATTTCTTAAATAATATTTTATTGATCAGTTCTTGAT TGACATATATATTGTAATTCAGTCCCGGGGATAAAACATTTAAAAATGGGGCTAAAAGATCAACTCAGAC AATCCAGAGGGGATATGTAAAATAGCCATTTGTGTTCTTAAAAGGATGAGCAAAAGTTGTGGCACAATTT AGAATTCAATCCCAGGTTCTAGTGTTGCAAAATAAAACAAACCTATTAGGCAAATGCAGATAATGTCAGC TTAATTTTTTCTCACTGCATAATTATAGTATATTAAACACTTAAAGTAAAAAATCTGGTTAGCTTTGCCA TCTACATATCTAATACACCATCTTCATTGCATCCAAGATAATGAAATATCTATAACCCCAAAAGTTTCCT GTGTCCCCTTGTTATTCATTGCCCTGCCCAGTATTCAGGCAACACGGATCTGTTTTCTGTTTTAGGTTAG TTTGCATTTTCTATAAAGTCTTATGAATGAAATAATAAAATGTGGACTATTTTCATGGGCCGGGGAGCAG TGTGGCTTCTTTCATTTCAAATGATTGTTTTGAAATTCATCCACAGCGTTGCACGTATCAGTAGTAGATT CCATTTGATTGTTGATTTGTATTCTATTGTATGCCTGAGTCAAAATTTATTCATTTCTTTGTCTGTTGAT AGCCATTTGGGTTCTTCCAGTTTGGGGCCATTACAAATAGAGGTACTATGAACATTGTGTAGAGGCTTTT GTGTGGACATAGGCCTTCATTTCTCTCTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCCC AGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAACCTCCACCTCCCAGGTTGAGGTGATTCTTCTG CCTCAGCCTCCCGAATAGCTGGGATAGCAGGTGTGTGCCAACACACCTGGCTAATTTTTGTGTTTTTTAG TAGACACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAGCTCCTGACCTCAGGTGATCCACCCGCCTT GGCCTCCCAAAGTACTGGGATTACAGGGGCTAACACGCTTTTTTAAAATGAAATATTTAAAACCTAAAAG CATAGTATCAGTCTGCCCAGGTTTAGTGAACCATAGTATTTGTCTCTTCTCTCCTCCCTCCAAGAAACAA CGTGTAACTATTTCATTGAAGCCTTTCTTTGGGCTCCCCCAAATCCCCACTTTTCTCTCTATTCTTAAGT TAACCATGATCTTGAAAACTGAGAATTGTCCTTCCTGATGGTGATGTGCTTTACTACGTAAATATTCTCC CGGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCATGTCATATTTATT GTTTTATATATGCCACTTCCTGAGTGAAGCTTACACAGTGGTACACTGTATGTGTTGTTGAGTATAGTCT GTCACTCAATTTAAGTTTTCAAGATTTATCTTTTTTTTTTTTTTTTTGGCGTGGGGGTGGGGATGGATTT TTGCTCTGTCGCCCAAGCTGGAGTGCAGTGGTGAGATCTCGGCTCATTGCAACCTCCGCTTGCCGGGTTC AAGCAATTCTCTGCCTCAGCTGGGATTTATCTGTTTTGTCACAAGTAGATTTAATCATGTCATCATGGTA GTTACACTGTGTGATTATAATACAGTTCGTTTTTTCGTTCTTCTACATAAAGACATTGATGTTTTCTTCT AAAACTTTTGTATTCCAAAATAGGCTTGGATATATTTCTCTGTGCACCTCAGTGCTCCTGTAAAATAGTG ACATTCAAATGTGAGTGTTGGGAATGTGTTGATTTTCTCAATGAGTGGTAGGCACCTCAAGCATTTGAGA GGTGGAGGTTAAGTATGTTTTAGGGTGAATAAAATCAAGTACCATTTTTAGGGTGAATAAAATTCAAATA TGGGACATTAAAATAATTTGAAAGTATAGTGATACGTGAAGGTATTTTGAGTAAATACCAACTAAAAAAA ATATAGTTTAGCAATATTGGAAGCCAAAAACAGTAGTAGCAGGATAGAATAAGACTATGTCGTATTTAAA GGAATTGGTCACTAAGTTGATATAACAACCATTAGTTTGTATGTGCCTAACTATGTATCCTCACAGTAAA AGTAAAAATTATTTACAAATTATAAGTCTCTATAGATATGTACAGTCATGTGGGAGATTTTAACCAATGA TATACGTCTAGCTGATGAATACTCTTTTAACATTTATATGCTAAATAGAATATTTTCACTACAGTTAATA TATGTAAGCTAACTATAGAAAACTGTGTACCCAAGAAATAAGTTTATTTACAAAGCATGAATCATTTATA AAAATTGACTGTATACTTGTTCACAGTCTTAATAAATTCTCTGAACATACTGAAATTAAATTATTAATAG AAAACATACACAGTGGGAATCCTAGGAAACATGCTTGTAATTGACTTAATGAGGGCCTCATTAAAAATAT TTAGACCAGAATATTGAGAATGCCACATAGTTAAACTTGTGAAGAGCAACTAAAGCAGTACTTAGAGGTC AATTAGTAGCCTTCACTAAGGTTGCATTTTTAAATCCTGTAAATAGCACATCTTCCTTTTCTTGAGCTCT GTATATTTTACTCAGAGTCAGAAGACTAGGAAGCAGTGGATCTAGCATTTGAATTTAGGAGTCTACATTC CAAGACTTGCTCTTCTTTGAGATTCCAAATAGAAACTATTTCTTTATTTCTCATGCAATTGATTTTTTTC TCTGATGTGTCCTTTGCCTGTAATGTGTAGTGTGGTGCATCTTTGTGAAATTTCTTAGGCTTTAGAGAAT GAAGCCTTTCAAACAACTTCGGATGTTTTCCCAATTCTCTTCAGAGATAGTTAACTGAACTGTGGTCATA TTAATGCCAAAATGTGTTTTATATTAAATAGCCATTGAAAACACAATGTTTTGTTTTCTATTTTAAAACT ATTATTATTTTAATCATTAAAAAGTTTGATGATAACATGTAAATGTGTTGTCAAAATATAGCAGTTTGTG AAGTTGAATTTAACTCAGAGTACTTTCTGTGTTTTGGAAAGAACCTTATTAGAAAAAGTGCCCGCTGTGC TGGAAGAAAGGGAGAATGAATTAATAGCTGTTAGTTTGTCACATTTCTATTTCAGTAGAGATTCAAGGAG ATGGTTTACGTTATTTTAGAGATTCTAAGGAAGGTATATAACATTTGGTTCTGCATTTTTCTTCAGTATG ACAAAAGAGTAAGCAAATATTTGCCAAAGAAGAAACAAATAAACCTGTGAGATAAACCTGCATTTGTAAT CTGTATGAAGTAAAAGTTACAGTTTACTGTTATGAACATTGTACTGTTTTAAAAAACCCACATCTTCCAT TTTAGACATACCATTCCCATTCAATCCATATGTCCAGTCATCTTCAAAATTTCTTTTGACTGTTTACATA TGAATTCACCTGATTACATTTTTCCATTCACCAAGACCATAAATTGACATTGCTCATCTTGTCAGTCTTT TTTTTTTTTAATTTTTTTCTTTTTATTTATAAAAAGGCCATTCCATGTATCTCACCCAAATTTGTTGACT AAAGTCACCCCACATTTTTTTTTGGGGGGGATTACTTTTGAAGTATTATCTTTGTATCCCAAAGCAGGCC CTTCTGAAACTGATGATGTTGATGAAAAACAGCCCCTATCGAAGCCTTTGCAAGGTATAATCTTTTCACT TCCATTCTCCCACATACTGCTTGTGTTTAATGTTTCCTTATATTGCACAGACTGTGTTTTAATATTTATA AGTACAGTATTACTTTTCTAAATGGAAAAGGAAAAAAATGTATTGGCCTTTTTTTAACATATAAATGAAC TTCACAAGCAACAATTTTTCAAAAATCAATTTTCCCTTTTGTGAATCTAGTAATGAATCTCGAAATGGGT ACATGACACACTTTCCTATTGAAGGTAAAGTACACATTTATACCTTATCTCAGAACAGTCAGAAGCCAGG TTACTGTTTTATTGGTTAGTGATGCAAATATTGATAAGGTCAGGTTGATACTTAGTATTTAGAAGAATTC TGAAATAGCACTTGTTAATCTGTAAGTTTCGAATTGATTGCCTTTTTGGCAATTTTTTACAGTGTTCCCA AACTTGATACTCATAGGCTATTAGTAATGGCATTTACTTCTATCTATTCTGGCTTTGAGTGCATAAGATG TATTTTCTTTAGGCTTAGCATATAATGTAAATGTAATTGTTTATTTCAGATTTTAAAAGACATACAGAAT TATTGCTTACACGAACAATCATCTTAACTGTTATTCTTTGCTGAAATTTTACTTTTTACCTACTGGCCTC ATCATTTCACTCTCATTCCTTTGACCTCACATCTCTTTTTTCTTTGACTTTTACAGTCAAATAACTTAAT GCTCCATAAATTCAAATATTAAGATTAAAAAAAGAGAAAGGAAGTGTGTAGAGAAAGCATATTTTAAAAA TGAATTAAAGAGTGACTCATAGGTATAGGTTTGTAGATTTACCTAGAGTTTGAGTTCAGGTGAGTTTTCA CAATATAAAGTAAGTGGAAAAGAATCCCCAGATAATTGTGACATGCTAAAGCTAGATACTGAGAACCAAA AAGATGTGACCTCAGTATGGGACTTTTAATTCAAGGATATTAGCTACCAAATGACAGTTTTTCAGACCGT AAGCATTGCTTTTTAAAAATCAAGATAAAATACATTTATAACATATCTTACTTTTAGTATAGCTTCTGAA TTTAGTTCTCAATAGATAAGACAAAAGAGATGAACATCTGCTTCCTTTCCCCTCAAGCGATGTATTCTTA CTAATAGGTAATATGTTTTTTTTTGGTACTTAAAGGCAGTGTTTTTCAATCTTTTCCATGTTAGTAGCTC AGATCTTTAAGGACAGAGGATACAAATTAGGGGGCAGCTTGCGTTCTTAATCCTAAGTGGCTCTCTGATG TCTTAGATTCTTCCTTTCCTTTTTGTGAGTAAAACTTCTGCTCTAGTAGGATGAGCCTGTTCACCTTGTG ACTGCCTAACTGATCATTGCTTTATGTTCCAGTTTTTAGAAGCAGGCAGATTATATTACCTGACTTAAAA TGCTTTTGAGACTAAAGGTAGTATCTTAAATTTTAACTTACGAGTTTCCTTTAAGTACAACTTTGATGAA ATTATGGGGATTGAGTTTCCATGGCTTTCACCATAGTGAAAATGGAAAGCATGAAACATTCCACAGCAAA CCCTGAACTTATTTATAGGGAGTTAATTAAGTGTCTGATCACAGCAAGCATTTACTCTGATCTGTTTGTG TATGTGTGTCTTTGACAGATGAGCATGGTACTTGAAGCATAATTCTGCTTCCTCAGATTCCAATATCTAG TAATTTTATCATGTAGTTATAGTAACTAATATTAAATCCCCAAACCTACTTAGGTCTACTCTGTATTTGT GTTTTCAAATAATTTTTTTAGCTTCCAAATAGAAGCGTTGTATTCTTTTCTGAATTAGAAAACATTGTTC GACTTAACTGCTAAAGAGTTAGACAATCATTTTGCATATGTTTATTATGTCTTAGATTGTTTGCATTGTT ACCTAGATTCTCTTTCATCTTTCAATGTCAGTTTTTATTGGTTTATTATATGTTGTTTATTTTCTTTTTA GGAAGCCACCATTCTTCAGAGGGCAATGAAGGCACAGAAATGGAAGTACCAGCAGAAGGTTAGGAGAAAA AGAGATTGCATATTTTCCACTATTTGTTGTATGTTTATTCTATTTTATAGATTCTATTATCCTTAAAACA CCTTATTTGGAAATAAAAGGTGATTCCCTTGGTATGCCTTCCTAGCCAACAGGTTATTATTTTTTTAAAA ATTCTAAGATGTAATATACTTCTTTGACCATACTGATTAATAAAGCCTATGGGAATGAAACTAAGTGGTA AGTAAAGCTCTTACATGATGCAAAATGCTACTTTTTTTTTTGTCCTGGTTTTCTTGTGCCATATTAAATA TCTTTTAAGGAAGAATAGCTTCAGTGTTTCAGAATTAAAATTACTAGCTCCATTCATATTTTATTTTCAA ATGTATTTTTTAATACTTCTAGTCTCTTAGTAGGGTAGGAATTTAGTCTACATAAAATTTATACAGGAGA GAGTTTCTCCCTTTATTTTGTACTCACAACTACTCCATAAATGACTTTGTCAGTTTACCAGCTCTACAGC TTTGGTTTTAGAATTGAACGCCTGACTGAGGTACAGTTCTTTTTGTTTAGAATCCTGAGTTCAACTTATC ATGTAGGGTGGCTTCTTATTTCCAAGGTGTTTAAACGGTTCCACACAAATTTTTGTAGATTTCTCCCAAG GAAAATGACTGGTAAGGTAACTGAATCTTGTTTTAGAATTATTTCTCTCATAAATTGGTCATGTTATCCC TTATTTTTCTAGAATGAAAAGAGGAGTCTGTTGTGTAACTGCTTATATTCCATTGTATTTACATTTTTAT TTTAATTAAAAAAAAACATTTGTTTGATCTTTTACCTTCTTTGAGGGAAAGGCAATCTTAAAAGTTCCCC AGTATAGGCTGGTTTCTCCAAATTCAATTATAGAATTAGGGTTTCTCCCTGGAATACATTTCTCTCAAAA ATACTGATATGCTCATTGTAAACCGTTGGTTACATTTCCCTGTCAGCCCTTTTTATAGAAGATTGTGTGG GTGAATGTTGTATGCTTTACTGTGTGGAGGTGGGTATCTTCTGAGTGACAGAGTTTTCAGCTTTGAATAG GCGGGATTTAGAACAACAAGACCTAGGTAATAGATCATGTGCAGTACGAGGGCTCATTGGGCAGTACCGA TGGCTCACCGCCTTGCAGCCCCGCCGGCAGGTACTGCACCTTGAAGACTGCGTTTTTAGGACATTTTTAC TGTCATATTCCAGTGTTAACAAAGTTGAATCGAATCTGGGTTCTGGCCTTTATTCCTTTACTAACAAGTA AACATAATCTTTGGCAAATCAATTAATCTCTCAACCTTTGCACAATGAAAGAGAACTAATGAAAATACTC TATAAGCTTCTAGCACTAACACTCTGATGTACATTTGTCTTGTGTAGGAACAAATATGAATGAACTTTGT AATTTTTGAAATATGTTGCATACAAAGCCAGAGGATATAGTCTTGTGTGCACTTGTGACACTCAGTCTCT TGATAGGAAAGTCTCCATTGTAAAGCCTGGGTTGTGGTTTTATTGAACAGTAGAAACCACTCCTCACATT TCTGAAAGGAGAGAAGAAATTCTAACCAAAGTAGAAAGCATTTGTTTCTATCCGAGCATCTTCTAGCTGT GGCAGGAAATTCATTGTGACTTTGTCATATCCTCATTCCTCCAAGACTATGGGATTTTTTTGAGTCAATT TCTGCAGGTAACATGTTATCATCTAAATTTTTCCAGAGTTTTTCTAATTTTTGTTTTCTTTTATCCCTAT TTATAATGACAAGGGTCAAATTTTAATTTCATTAATATGAAATGAATGAAAATGCCAGTGGATTTTTATA GTAGGCTGCTTTTGGAGTATCAAATCAGTAAAATGTTGGAACATATGGAAACATGCTTAATAATGAATGT CATTTTAGAATTTTATTTTTTTCAAGATTCTACTCAACATGTCCCTTCAGAAACAAGTGAGGACCCTGAA GTTGAGGTGACTATTGAAGGTTAGTTATCTAAAAGCCTTGATTCCAAAGTTTACTTCTGGTCATAAAAAT ACTTGTCACATTCACATTGCTAAATATGCATTTCATTCATTTTTAAAGGAGACTTGTGGGACGAATACAT GTGTCTGTGTGGCCAAAGCAGCCCACTCCCCAGTGCTTTGGGAGTTTTAGATGACAGAATGAGGCCGTGA GAATTAGCATTGGCCCACGGGTGGCCCAAGCTATCCTTGCTATCAGTGGGAGTTGAAAAGAGAAAAAGAA AATTATGACCAGACTTGATACACACAAAAACAGATTCTATAATCTATTGGGTTGTGATAGAAGAAGACTT ATTTGGAGCTGGAATCCCTAATTTCTAATTAAGTAAAGTGGAGGAGAAAGTGTTGATAGTTTAGTGAGTA ATTTTTAAAGCAAGTCCCTGCCCCCTTCAACGACCCGCAAATACTACTTAGAGGCTGACATACAATTTAT CTTTCAAAACTGTTTTGAAGCAATAGCTACAAATATATTCTACAATACTCTCTATAGCTAAGATTGCTTC AAACCTGTTTTTTTCTCCAAAGATAAGCTTGAACTCAGCTGAGCCAGTTTATCCTGAATTATTTGAAAAT TCAGCTAATAGAATTATTAACTATCACTTCATATTAATAGTTATTAAATGAGCATTGCGTTTTTCCTTTT AAATTAATGTCTCACAGCTGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGTAG GCAGATCACCTGAGGTCGGGAGCTCAAGACCAGCCTGACCAGCATGGTGAAACGCCCATCTCTACTAAAA ATACAAAACTAGCTGGGTGTGGTGGTGCATGCCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAA TCGCTTGAACCCTGGAGGCAGAGGTTGTAGTGTGCTGAGTTCACGCCATTGCACTACAGCCTGGGCGACA GAGTGAAACTCCATCTCAAAAAAAAAATTAAAATTAAAATTAATGTGTCACAATACTTGTGTAAGTTTCT TCCCCTGAAAGTACTTCTTTCTTGTGGTAAAATGTGAAAATGGTACAGTAAATTGTACAGTGGAAAGTTT TCTTCACCCTCACTCTGCTCCCAAGTCCCAATACTGAGGGATGTATGCCAGCTTATTGTGTCTACTTAGA GAAATAATTGCAGTACATATCTTGATGCGAAAATACACAGATGCTTTCAGCATACATTACAATGCACATT TTAAAATATTACATATTCCATAGGCCTCCCCCTCCCATAACTGCACATCTTGGTACTTTATTAGTTTTTT TTTCTAGCTGCTGCGTAACCTTTCTTGGTTTGCTGTCTGTCTCTCTTTCTCTCTTAATAACCTGTCACCT ACTGATGTCACTTGGTTATTTCTAGTGTTTGACTACTCCAAACTACTCAACGTGTCTGTCTTCATTGCTT CTAAAATATAAGTCAATTAGTAGCTTCCACTTAATACAAGAAATCTTTTCATACTTCATGTGTTAACTTA ATATACAGATTTCTTTTTTCATAAATATAATTTTTCTAATCTAAAACATTTTGCATTGTTTACAGTCCAG CATTAAATGGTTGAAATTTAATTCGTTTTTAGTGAGAAACCTCATTAACAGGAAAAAAACTTAAGAACAT ACAAATATTACAACTACTCAGCTGTGCCCTTTCTATGGAGATATTAATAGGAGGTTATTAAAATTATAAA AATAAAGCTTTTAGGGTAGGACTAATAACCATTTTGATTTGTCAAATCTTAAAGCAGATAGAAGCTGTAT TTTTTTTTTTTTTTTTTTGAGACAGAGTCTGGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCGATCTCG GCTCACTGCAAGCTCTGCCTTCCTGGTTCACGCCATTCTCCTGTAGAGGCTGTATTAAAATGGTTTAGAA TGTAAATACTTGCTTTTATAGTATAAGACTTTTAAAGAAAGGTTACGAAAATCCAGAAATAAATGGCTCA TGAACCTGAAGCTTATGTCAGCCTTTTGAACTTTAACTGTTTTGGATGGAGTAATAAATCTCTTTTCTTT TCATTTATTTGTTTATTTATTTATTTATTTGTTTTTGAGATGGAGTTTCACTCTTGTTGCCTAGGCTGGA GTGCATTGGCGCTATCTCGGCTCACCGCAACCTCCGCCTCGCAGGTTCAAGCGATTCTCCTGCCTCAGCC TCCTGAGTAGCTGGGATTACAGGCATGCGCCGCCATGCTCGGCTAATTTTGTATTTTTAATAGAGACAGG GTTTCTCCATCTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCTGCCCACCTCGGCTTCCCAA AGTGCTGGGATTACAGGCATGAGCCACCGCACCTGGCCATTCATTTCTTTTAAACTAAGACATTGTGCCA TAAGCCTGATTTAATGTTCACATTTGTGATTAAGTAGTAGAATTTTGCTAGTAGACCTCTTTCTTTTCAG AAGACCAGTGAAATACCAGGTCTGAGTAAAGTAATCCTTTTAAAAGGTAGCATTTTCCATGTCATATGTG CATATACACACACACATTTTATGTATTATATATAAAAAATATGTATATTATATAGAAATTACATCAACAA TTAAATTCCTCATTTTTTTAAGAAGATAAAAAACTGTCTCAATATTAACAAGGAAGGTCAAGTGAGAACT TACATGCACACCTCTGGTTAATAATGTGTATCATATATTCTTTCTGGAAAGATTACTTCCAAATGGTAGG AGCTATTTAGATACCCGTAGTTAGGAAATAAAATTTTGGTATATCTTCATAACAGAAAAATATATAGCCA TTGAAATCCTGATAATGTTTTCCAATAATCTGAAAAAAGATCTCTAATATAAAATGTTCAGTGGAAAAAA AAAAAATCCTGCCTTGAGAACAAGGCAACTTGAAAAGCAAAAGTGCATCTAGAGGATAATCTTAGTTTTG TTTTGGAAAATACTCATGCTTGGTAGGAAGACGGACAAAAATAAACTGAGATATTCCTGCTTGCTTGGAG ACGACTTAATTTTCTCCTTTTATATCTTTTCACATTTCCCAAATCATTGGTAGAAAAAAAAACAGAACTT TGTTATCAAATAAGTCTGTCCGATTTTTCACAGTGTTTTCACCTCGATATCTTCATTTGCAATTATGTGG AGTTCTGAAGTGGCTAATTTGACACCGACGCGGACGTGTTTGTGGATACAGGGTCATTACTTACCCACTG CCGGTGCGCTCTGAGCTGTGCACTTCCATTTGTGGCGTTTTATTTGTACTTGGAGTCGGTGGTAAACATT TAAAACATACGTGACTTAGGTTTGGGAAATCGGCCTTGGACTAATAGGACCGCATGCCTCAGTTTTCGTA AACACCGTGACTACATTTCTGGGTTAAGGTGAATTGCCGTCAGGTATGTTATCTCTAATGTGTGCAGAGA AAACCTTATCAGACTTGTTTCAGGTCTAGCTGTCATGGGAGTGCTAAGAACCGTGTAAAGGAGGTTTCTT TCTTGCGCAGTTCTCTCTTAGGGCCTAGCTTCCCAAACCTGAGTCACTTACCTGTTACCTGTGTTCCTTC TGCTGTGGCCTAACTCTCTGTTCATTACTTAACCTGATTTTTTTCCCTTAAATTGATTTTAAGTAAATTC ATTTTGTGATGAATTTTACGTCTTCCTAAGTCAAACTCTGGCTTTTTTATTTCTCATATTTTGAAAGGTA TATGTAAATAATTTCAAATATAATTGACTCACATGACCACACGTGGCACACTTACTGCAGCTGGTACTGT AGGTTTTTTAGGATCTCTGTAATTGAGGAGGTTAGCGTTGGAAAACTTCTGTGTTTTTTATTTTTATAGC TGCCAATCAGACACTTAATGAATACACAATTATATATGTAAAAAAAGGAGTCTCAGAGGAATTATGTACT AAGATTTGAATAATACGTTTTTAGAGTTTCAGTATTTTAGTAGGGTTTATGATGGGCAGTTGGACTACCT ACCATCCCTTTCTTGTGGAATTTATGTTTAAGATAGTGCCAGATACTTGACTGCAGCATATAATTAGGGA CTAAACTATTCATATGTTCATTTAATCCCTCCACAAATACTGAGCACATTGTATGTACCAGGTGCTAAGA GTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTC GGCTCACTGCATCCCCTGCCTCCCAGGTTTAAGCAGTTCTCTGCCTCAGCCTTCCTCCGAGTAGCTGGGA TTATAGGCGCCCGCCACCATGCCTGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATTT TGGCCAGGGTGATCTTGAACTCCTGACCTCGTGATCCGCCCACCTCACCCTCCCAAAGAGCTGGGATTAC AGGCATAAGCCACCGCTCCCGGCCTCTTTTTTTTTTTTTTTTTTTTAAGACGGAGTCTTGCTCTGTTGCC CAGGCTGGAGTACAGTGACCTGATCTCGGTTCTCCGCAGCCTCCGCCTCCTGGGTTCAAGTGATTCTCCT GCCTCAGCCTCTGGAGTAGCTGGAACTACAGGCACACGCCACCATGTCCAGCCAATATTTTACTTTTAGT ACAGACAGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTTACCTCAGGTGATCCACCCGCCTC GGCCTCCCAAAGTGCTAGGATTACAGGCATGAACCACCGCGCCTGGCCACGGTGCTAAGAATTTAGTAGT GAATAATTCAGTGGCAAATCCTCGGGAGTGTTTTGCAAATAAGAGTGACACTTTTTGTCCTTCACTTCTA GGAAACGTGGTGACTATGTTGAGAAAAGGGGGAAAAAAAAAAAAAGAGAAGACCTAGAGCAGTCAATAGT TTTTTGACAGAAAACTAGCTTGGGAGCCTCTTGGAACTACCTAGGGCACAGAGAAGAGTGCTTTAGAGCA GGTTGGTGGCAGGGGAGATAAGAAGTTGTTGATTCTGGGGAGATTTTGAAGACAAAGCCACCAGGCTTTG CTGTTTATTGTTTAATTCTTGTATTTTCTTAAATGTCTCTGCAGCACTTTTAAAATGGACATAATTGCTT AGGTTAGCACTTGAACACTTTGTTTTAAATTTTTTTTATTGCTGCCAAATAGTCATTTAATAAATACCCA ATTGTTTATGTAAAGAGTTTTAGAGGAGCTATAAGTGGTATCCATGGGTGAAAGAATGAATCCATTTATT TGAAATGTATAGGGTAATTAATGGCTCCAGTTTTGAAATAGATATATTACCTGGTGTTGATTGTTTTTTT AACTTTGAATAGATGTCAGATTGTATGATAACACATTCCCAGTCTGATTATGTTGAAGCTAAGAGTATCA GAACATATTGTAACATAGTCTATTTATTGATTCACCGGCCAGAATGCAGTGATAAACAGCTTTAGCTCTG AAGCCTGTATTATCTTTAGGTGTATTCGTTAATATGTTGCAAAAAGGAAGTTGGTGTTTTCTAAACACAA ATTTTGAGTTAGGGACGGTGTTGCCAACTTGAAGGTATTGGCGGAGTGCTTTTGTTAGTGTGGGTAGCAT AACTATTGTAAATTCATGAATAGCACCTTTTGCATATTAAAATATCTTAAAATGGGCCAGGTGTGGTGGT GTAATCCCAGCACTTTGGAAGACCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGAC CAACATGGTGAAATTCCATCTCTACTAAAAATATAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAAT CCCAGCTACTCTGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAAGTGGAGATTGCAGTGAGCCAAG ATCGTGCCACTGCCCACTGCACTCCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAATAAAATAA AATATCTTAAAATGTATTTTAAAAGCTTTACATTTTGATTATGGAAACAGAGTTTGGGCTTGAATTTGAA GCATGCTGAAACGTGTGTCTTGTTAAACAAAAATGGTTGTTTATACTTTGGAAACGGCAGATAATTGGAA GAGCAATGCCCAGTATGTGAGGGCAGGCCCTAGAGCTTTAGTTGATGTTTTATGCTTCAGAGTAAAAAGT AATTTTGATCCTTTGTGGAAAGGATTTTAGGTCGAGAAACCCATTTTTTTTCTTACTTTCTCAAAACCAA TTAATTGCAACAAAGAGTTAATTGCAGAAAAAATTGAGGATGTGGTGAAGTTTATAGCTGTTCTGATGCC TGAATGCCATGTTCCATATGACTTAAAACACCCAAAGATTAATTAATAAGTTTATGAAACAGGGTTTTTA AAATAGAATATATGGTGTGATATTTTATCAATAACTACATCCAGCTGGGTGCGGTGGCTCACACCTATAA TCCCAGCACTTTAGGAGGCCAAGGCAGGAGGATCACTTGAGGCCAGGAGTTCAAGACCAACCTGGGCAAC ATAGGGGGACCCCTATCTCTACAAAAGTTAAAAAAAAAAAAATTAGCTGGGCGTGGTGGTGCAGGCCTGT AGTCCCAGCTATTTGGGAGGCTGAGGTGGGAGGATCACCTGAGCCTGGGAAGTCGAGGCTGCAGTGAGTG GTGCTCCAGCCTGGGTGAAGGAGGGAGACCCTGTCTTAAAAAATAAAGTAACTACATTCATCTCTATATA TGTTCACATTTAACAGATTGAACTTTATTATTTGTCAGTGAAGAGGAAAATGTGATATCCCTGATATTTT CAATATTTTACAGTCTTTGTTGTATTAAAAAAGCACTCTAGTAGATTTGCCTTTTTCTCTTTCTTTTTTT TTTTTTGGTTTATGATCGATTGGGTTACCTTCATAAAATATATTTATGCTATTAAATCTATTGTGGTCTA AAATGTTTGTGTGACTGAAAAAGTGAAGTCTTTTCAGTAAGGAAAACCTGTCTTCCCTTCCCCTGGGCCT CAGCTGTGAAGTTTGGATTTGGACTGAGATCCATGGGATGGAGCTCCACAGGTGTCCCTTCCATTCCATC TACAGCTGTGTTTCCTTTCTCATGTCATTCTACTCTAGCAGCTTTCAGTTTATGTCACTCAATGAATAGT CAGCTTAAATGATGATCTATAAGGATACTTAGGAGACCTTAACCTATAGGGGAAATACTTTTATTTTAGA AGTTACTGCTTAATGTTTGTAAAAAAATATATAGTAATATTAAGCATTTATAATGCTTTGACAGTATTCA TAGGTGAAATGAGTGTATTTTGTTTTAACCTTTGGAAGCCAGCATAAAAATACTCTTAAGGTTTCTAAAA TCTGTTTGGGAGTTGGAAAATCGGGTTTTTTAAAAAGTATATTTTCAGAATTGAGGTCCAAACTTACACA CTTCTGTTTTCCAGATTGTTTCTACTTAGGTTGGAACCTTAATCTATTTATAGGGTGTCTTGACCATTTT TAATCCTTACAGTCATACAAACCCAGGTGCCAGTCAAGTTTTATTTCACAGGGAGGTTGTCATTTTAAAA TTGTTTTCTGTCCTGGTCCCGTGGCTCATGCCTATAATCTCCGCACTTTGGGAGGCTGAGGCAGAAGGAT CACTTGAGGCCAGGAGTTTCAGACCAGCCTGGGCAACATAATGAGACCCTGTCCCTACAAAAAATTAAAA GAAAAATAGCCAGGTGTGTTGGTCCCAGCTATTTGGGAGGCTGAAGCAGGAGAATCATTTGAGGCCAGGA GCTCGAGGTTGCAGTGAGCTATAATCATGCCACTGCCCTCCAGCCTGGGCGATAGAATGAGACCCTCCCG ACAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGAATGAGACCCTGCCAATA GATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGAAAGAATGAGACCCTGCCGATAGATAGAT AGTTTTCTATCAAATTTTTTCCTAGATTTGAACATGTTTTTCTAAAGTAGCATTCAACACATCAGCATTT TATAGCGTCATTAGTTGTTACTATGATTATGTTTTTCTGAAATAGTATCCTTTACAAAAGCACTTCTGTC TTTCTAAGCACATACATAGGTCCTAAAATGAATTTGTCTGATGTTGGTGACCTCGGAACCATTTTCTCCA GTTGATTAGCACGGCCAGCCAGTCAATAATTTCAGGTCACTGTTGGCCTTAGAGGAAGAGCCCAAAGGCA GCAAGCAAGGGTGCTGGTGTCCAGTCGCCTTCTAGAAGCATTTTCACCTTCCCTTAAGATTTCCCTTGAT TAACACAGAAGTGTCTATAGAAGTGACCCAGTGCTGCCCCGGGCAACATCGTATATTAGGCCAAATTTGC ATTTCTTACCTTTATGAGAAGCACCCTCGTAGTCTAGTGGAGTTACACACACACAGTCTGATCTCAGCTG TGCTCTCCAGAGATACAACATAGTCCAATCAAATAACATCCTCTGAGCCTGTTTCTTTAGCTGTAAAATA AGAATAACAATTATACCCATCTAAAAAGATAGTGTCTTGTACTTGAGTGATCTTTTTTCTATGATACTGT CTTTAACACAATAATTATTTTCTTCACCATACCACATTTGTTTTTAAATAAGAATTTCTTAAAATGATGT TTTCAGTATTTTATAGATGATGTTTGAGCAGCAATATTAATAGCATGTTACCTGACACTTTGAGGGACTA GAAGATGACAGTGGCAGCTGATATGACCCAGATGTCTCTAATCCTAACATGAGGTGTACTGAAGGGTCAC AGCAGAGTGAGTTCCTGGTGTATCCACAAGGAAATGAGCACGGAACTCTCACAACAGCGTGTGTGCTGTG CGCTGTGCTTGAATAGCTGACTGCTCCTTTATACACAGCCTCTGTGCTGACTGAATCAACAGTATCTGTT TCATCATAATGCAGCCCTATTTCTTTAAGCCCATACATTTTGCACTTGTTAAAAGTATTTGAACAGGCCA GGCGCGGTGGCTCACACCTGTAATCCCAGCACTCTGGGTGGCCGAGGTGGGTGGATCACTTGAGGCCAGG AGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCCATCTCTATCAAAAAAATACAAAAATTAGCCGGGC GCGGTGGCGGGTGCCTGTAATCCCAGCTACTTCGGAGGCTGAGGCATGAGAATCGCTTGAGCCCAGGAGG TGGAGGTTGCAGTGAGCCAAGATTGCATCACTGAACTCCAGCCTGGGCAACAGAACAATTCTCTGTCTCA AAAACAAAAACAAAAACAAAAACAAAAAAAAACTATTTACCCAATTTCCCTTGCTTATGCATGCTTAAAT TTTGTATAAGCTTAAATATCTTTTCCATCTAAGCTGTACTCTATCCCCTTTTATAACTTTAGGTGGCTGT CTTTATTAAAAGTTTTTTCTTGAAAGTCTTAAAACAATATAGTTCTTGGCAATTTGAAAGTTATTTGAGA AGGGGAAATTTATAATGACAATTCAAATGAAGCAAACTAAAAAATAATGAAGAAAGACAGAGGAAAAAGC AGTATTCACTTGAACACATCCCAAACAAAGAAAATTTCAAATGTAACAAGGAAAAAGCCTGCTAAAGCTC ACAATACAGAAATAACTATTGATACTCAAAATAGCTTTAAAGCCCTGCTCACCTTTTGAATGTTGGGAAT TGACCAGGAGGTGACTGTAACTGTAAGATGGTTCTTCCAGTAATGACCATTTTCTTTTTCAAGATGATGA TTATTCTCCACCGTCTAAGAGACCAAAGGCCAATGAGCTACCGCAGCCACCAGTCCCGGAACCCGCCAAT GCTGGGAAGCGGAAAGTGAGGGAGTTCAACTTCGGTAAGTTCTCAGCGAACGACGTGACCTTTTCCTTCA TCTTCTGGATTCTCAGTGTGACTGATAAATGTTGCAACATGCTCTGCAGGGGGAAAATGCTTTAGCGTCT ATTACTGCATCATAATCTCATCTTTGGAAAGCCAGGAGCATTTTGAAAATTACATTACAGACATTGTTTA AACATAGTTTGGATTTACCAAAGCATAGGACATTGTCTTGTCTGATGTTAATTAGTCAGCTCAAGATTAG TGCTAAAGACTTAGTAATTTAGTTATTTCTCTTAGCTTTAAAATCTTTATTTCAGAACTATTTCACCTCT TGGTTTTCTTTTTTTTTTTTTTTGCTCTGTGTTACTGCAGCTGCTAATCTGTGAGCTCTCAATGGATGAT GTATCCTAGCAAGGGACTGAATGAGATATTAGCGGCAAATTATGTTGATGATTCATATTTTGAATAAATG GAATATTAAGCTTGTATACATCTTGAAAATAGTACTTTAATATTCTACTGTGTCGTAGTCACAATGATTG GATATGAATTGAATTTTTGTACTTTTTAAATATGTTTTTGTTCTTTATTTTTAATTTTTATTATTATTTT TTTGAGACAGAGTCTTGCTCTGTCACCCAGGTTGGAGTGCAGAGGCACGATCTCAGCTCACAGCAACCTC CGCCTCCCGGGTTCAAGTGATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCCCACCACC ATGCCCAGCTAATTGTTGTATTTTTAGTAGAGATGGGATTTCACCATGTTGGCCAGGCTGGAATCGAACT CCTGACCTCAGGTGATCCGCATGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACT TGGCCTGTTCTTTAGCATTTTAAGTTGCAACTATATATCCGTAAAGTCTTATTTCCACACAACTGAGACA TGTTTTAGGAAGTTTGCTAAAAGACCCCTGGAGACCTTTATCGTGGTCTCCCTTTTGTCGTGTTTCATTT GCTTGATCTTTTCTGCCCTCCTGCTTTTCAGAAATTAAAAGGCTAAAAAGAGGTGCTAAATGTTAAAACT TCTCGTGTAGTCTCCCATGAGACTATTAAAAGTAATGGCAAAAGCCACAGTTACTTTTGCACCAACCTAC TAATTCTAAGAACCACCAAAAAGGGGAAAGTTCTTGGAAAGCAGTAAAATGATATGGACAGTTGGGATGT AAAAATGTAGAAAATATGTCATTGTATGTTCAGTCATCCCAAGACCCTAGTGCTGCCCCGATGGTAGGGA CTTCTTAATGAGAATTAACTTTTGCTCAATTTTCAGAGAAATGGAATGCTCGCATCACTGATCTACGTAA ACAAGTTGAAGAATTGTTTGAAAGGAAATATGGTATGTCTAAATAGGAAAATTCCTGTAATACTTTGTTC ATGAGCATTTACACAATGGCGTTACTGTTCATCATGGGGGTGATGTGGACAAGCCCAGCCCAGGGCTGCC AGTGAACCGTGCCACACTTTCTTACACGTCTCTCATTGTAAGGTCCTTAGTAGTGTCTGTCTAAATATTA GAAACAGTCTTTGTTTCTAGATTACAGTAAAGCTAAGGAAAAGTTGTATTTCTGTAGTTATCAGCTAACA TTTCTTTTAAACTTCCAGCATGGATATTTGGGAATTTATTTACATATTTATTACAAAGCTCTGGATCTTG GGGGTTTCATTAAAAATTATTTTTTTAACTGACAGTTTCTGTTAATCTACTTTGTTAAATCCAGTATTTG CTGAGATCCCCCTATTGTCTCTACTTTTATCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCT CTGCATTGCAGTAGTACAATCTCGGCTCATTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGGCT CAGTCTCCCAAGCAGCTGGGACTACAGGTGCCCGCCACCATGCCCTGCTAATTTTTGTATTTTTAGTAGA GACAGGGTTTCACCATGTTGGCCAGGCTTGTCTCAAACTCCTGACCTCAAGTGATCCTCCCGCCTTGGCC TCCCAAAGTGCTAGCATTACAGGCGTGAGCCACCCTTCCCGGCCACTGCTTTTATCTTGATGTATAACTG AGTTGATGCTAGATTTCAATTCCTTCTTTGTCCTTTTACTATTCTGTCCTATAGCCACCTTTATATAATG ATCAAAGAAATTCGCAATTTGTTATTATCATTTTTATTTTTTATAAAATATTTAAAATGATTTAAAATAA AAATCATTTTATTTTTATCATATTTATTATCATCTGTTATCATTTTTATTTGGATGACTATTTACTTTGC CATTAACTAGCAAGCGGTAAAATTGTATGATATGCAGTTTTAACTGAATTGCTATAAGTGAAAATTTAAA TGCAATAAACCATATTGATGGTATTTGTGTTAACAAACTTAAAATGAGCATTTTTTCTTCATCATGAGTA ATATAACCTACCCCTCAATGAAAATCTACAATTAGAGTAAATTTGCTAATGAATTCAGTAACTTTTCCAT ATTTTTAGTGGTTTACTTAAGGTTCTCTTAGTGTTTCTCCCAGTTTTTAATAGCTTACACCTTTTTTGCC CGTGGTTTTTTGTTTTTTGTTTTGTTGTTGTTTTTTTTTTTTTTGAGATAGAGTTTTGCTCTTGTTGCCT AGTCTGGAGTGGCACGATCTTGGCTCACTGTAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGTCTGA GCCTCCTGAGTAGTTAAGATTACAGGTGCCCGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGA CAAGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTAACCTCAGGTGATCCACCCACCTCGGCCTC CCAGAGTGCTGGGATTACAGGCGTGAGCCGCTGCGCCCGGCCTCATGTTTTCTATTGGTTCATTATGAAG CAAAAACTTCATAGCATGTGCTACCTGGAAGCACTGTAACCTAGTGGTAAGATCATAGGCTCTGGGGACA CAGTGCCTTGCCACGTCTCTTCTCCTGTCTGAGTCTTAGTATCCTCTTTTGTGGTCATGAGAACTGAAGA TCTATCCTGGAGATTGATAAGATAGTAAAGTGCTTCACGTAATACCTGGCATACATGTAATAAATGCTTC CTGTGTGTATATATATACACACATATACATATATATGTATATATACATATACACATATACATATATATAT ATATATACATAAACACATATACATATATATATAACACAGTGAAACCCCCGTCTCTACTAAAAATACAAAA AATTAGCTGGGCGTGGTGGCGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGT GAGCCCGGGAGGCAGAGCTTGCAGTGAACCGAGATCACACCACTGCACTGCAGCCTGGGAGACACAGCAA GACTCCATCTCAAAAAAATAAAAAAAAAGTTAAAGAGCACTACAGATTCAATGATTTATTATTCTTTTCT ACAAATTGTGTTTAAATGATATCTCTTTCTCTTTTTGTCCTTATAGCTCAAGCCATAAAAGCCAAAGGTC CGGTGACGATCCCGTACCCTCTTTTCCAGTCTCATGTTGAAGATCTTTATGTAGAAGGACTTCCTGAAGG AATTCCTTTTAGAAGGCCATCTACTTACGGAATTCCTCGCCTGGAGAGGATATTACTTGCAAAGGAAAGG ATTCGTTTTGTGATTAAGAAGTAAGACTCTTGGATTCCTGTTGAACTCTTGTCTCTTTTCTGAGTAATAC GTCTTTTTTATTGTTGACCAATATTCATTCACCACTAGGTTCTATGTGATGAAGTTTGAGTTATTTTATG TATTTTTATCTTGCACTTTTTAATTTATCTGGGTCCAGCATTGCATCAGTCATGCAGTGTTGGCATTCGA AGCATGAACAGTGCCCGCACTGGATTGGCATGCAACTCACATTTTCTTTCACAATTTTCTGCTACTTTTG CTAAAGAACATAGAATCCACGCCTTGTTTTTAGGCCTGATATATATATATATTTTTTTTTTCGAGATGGA GTCTCACACTGGAACCCAGGCTTGAGTGCAGTGTCGCAATCTCAGCTCACTGCAACCTCTGCCTTCCAGG TTCAAGCGATTCTCATGCCTCAGACTCCCGAGTAGCTGAGATTACAGGCGTGCGCCACCATGCCTGGCTA ATTTTTGTATTTTTAGTAGAGACGGTGATTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAG ATGATCTGCCAACCTCGCCCTCATAGGCCTGAGATTTTTAAAGCATGCGTGGGAATATATGATTGTTTTT ATAGATGTGCAGAGGAAGATAGTCTTGAATGCAATATGACATTAAAGGATCCCATTTAAGATTTTTGTAA TATGCTTCAAAGACCTGTGGGTTGCAAAGTTACCTCTTTACTTGTGAGGATACATGCTCCATGAAGCACC TTATGAGACAACTTGCAATTATTAGTTTGCTTTTTACTCTGTAGAAACCTCAAATTAAGATTTAGTTGTG GGCTGGGTGTAGTGGCTCACACCTATAATCCCAGCACTTTGGGAGGCCAAGGCGGCTGGATCACCCGAGG TCAGGAGTTCGAGACAAGCCAGGCCAACAATGGTGAAACACTGTCTCTACTAAAAATACAAAAATTGACC AGGTGTGGTGGTGGGCGCCTGGAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATTGCTTGAACCCGG GAGGTGGAGGTTGCAGTGAGTCGAGACTGCGCCATTGCACTCCAGCCTGGGAACAAGAGCAAAACTCCGT CTCAGGAAAAAAAAAAAAAAGATTTAGTTGTGCTCAAGCATCCAGATTATCTTTTCTTTTCAAAACCAGC CTTACTGACTAAATGTTAAATATGTACTAGTCGTTATTAGTTTGCTGAATATTACCTAGTGATTATTGAG TATTTATTCTCACCTTTCAGACATGAGCTTCTGAATTCAACACGTGAAGATTTACAGCTTGATAAGCCAG CTTCAGGAGGTAGGTCTTCAATCTCGAGGCAGATCAGAAGATTATGTGCAATAATTATTTCACGCTTAAC ATTGATTTCTTCTTTATGTTACCTTCCACATGAAATAATATGTCTCTAACTATTAATTATGTGCCATTAC AGGAGAATTCATGTTGTCAAAATTCTAATAATTTCTAGAAGAATAAACGCATCTTCTTTTTATTAACCCA TTGTAAATACTTATAAATATTGCATTTATGGGTAGACAGAAGTAAAAGAACAATATTTGTTCTACTTTTG ATGCAAGATTTATCTGGCATAATGCATTGAACAGTTTATTATTGAAGTCTACACGAGTCAATGGAACAAG CATTCATTGAATGTCCATGATATGCAGGACATAAGAAGGTTTCCTTTTAGAGCATGGAGCCATTTATATC ATCTCTTAATTGTTAGATGTATTTTGTTTTGTTTTGTTTTGTTTTTTGAGAGGGAATCTTGCTCTGTTGC CCAGGCTGGAGTGCAGTGGTGCGATCTCCGCTCACTGCAACCTCCCGCCTCCTGGGTTCAAGCAGTTCTC CTGCCTCAGCCTCCCTGTAGCTGGGATTACAGGTGCCTGCCACCATGCCCAGCTAATTTTTGTATTTTTC GTAGAGACAGGGTTTCACTATGTTGGCCAGGCTGATCTCAAACTGCTGACCTCAGGTGATCTGCCCACCT CGGCCTCCCAGAGTGCTAGGATTACAGGCATGAGCCACCGCGCCCAGCCTGTTAGATGTGTTTTAAAATA AATAGAAATATAATTGATTTTCTTGCTTGCTTTTGCTCTGGAGTGGAGTGGAGTGAGGATAAAACAGAAT GGAATCACCCTGTTGATATTTACTAAGATAGAAGGACTGCAGCAAGATCATAGCCCTAATCTTCCTGTAG CAAGTGTTACCTGCTAGCTGTTCCTGAATACACTGAGTTTTGCTTTTTCCTAGCTCTAATGAATGTTTCG TTCTTCCTCTTTTTGTACAGTGTCAGCATTGTTTTAGAAATAAATACATTCTAGAATCTTAGGAATAATT TTATTATTGTCTTTTTTTTTTTTTGAGACGGAATCTCATTCTGTTGCCCAGGCTGGAGTGCAATGGCGCA ATCTCAGCTCACTGCAACCGCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCATGAGTAGCTG GGACTACAGGCGTGCGCCATCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGT TGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGACCCGCCTGCCTCGGCTTCCCAAAGTGTTGGGATT ACAGGTGTGAGCCATTGCACCTGGCCACGAATCTTAGAAATAATTTTGGCCATAGGAAAAGGAAAAGTTA TACCTCTTATTTTATAGTAATAATGTTTAATAATCAAGTTATTAAACCCATTAAATTGAGAACACTTGTA TTACTGTTATTTTGACAGTAAAGGAAGAATGGTATGCCAGAATCACTAAATTAAGAAAGATGGTGGATCA GCTTTTCTGCAAAAAATTTGGTAAGTCTGTTTTTTTTAATTACCCCTTCAACTAAAATGTATTACTGAGT AACATTTTTTTAAATGTTGTTTTATTTTAGGAAAGTAAATACAGTGAATAGGACTCAGCTTTAGTTTTCC CTGTTTTTTTTTTTTGGGTTTTTTTTTTTTTCTTGAGAAGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTG CAGTGGTACGATCTCAGCTCACTGCAACCTCCTCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCGTCC CAAGTAGCTGGGATTACAGGTGCCCGCCACCACGCCTGGCTAACTTTTGTATTTTTAGTAGAGATGGGGT TTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGAATTCAGGTGATCCACCCGCCTCAGCCTCCTAAAG TGCTGGGATTATAGGCGTGAGCCACCGCGCCCGGCCCCCATTCTATGAATTATCTGTGGAAAGTTATTTC CTTTAAAATGGCATGCTCGTGAGGTTGAAGGGGTAAAGAACATTGATCTGGTTGCCACGCAGATGAAAGT GTAGTCGGAAATGTGTTACCAGTTTGCCATAGCCGATGGAGGAGGGTAATTACGGTCCTGAACAGTTAGT AGCAAAAGGCTGCTTCCAGATAGTATTTAGGTTGTGTCCTCTATTGTCCATGATGATTTTCTTTCTCTCT TTTCTTCCTAAGGATATTGAAAAACAAACTTTAATCTTTTAAAGATCTCAGAGCTATTAAGATTGTCTTA GGACCAGGACACTTAAATCTGCCCAAATCTGGCTGTTGATGATCGGTCATCTCTACTTGTCTTTGCTGTA TTAAGTCTATTCAATAGTTAATAAATATGTTTCTAGAAAGAGTTTTTTTCAAGTAAAACAAAATTGACCT GTGCCTTTCTTTGGATTGTACTAAAATCTGATTTCAATACAAATGTAGTCTCCCGAATTGCTTTGATTTT TGTCCAGCGGAAGCCTTGGGGAGCACTGAAGCCAAGGCTGTACCGTACCAAAAATTTGAGGCACACCCGA ATGATCTGTACGTGGAAGGACTGCCAGAAAACATTCCTTTCCGAAGTCCCTCATGGTATGGAATCCCAAG GCTGGAAAAAATCATTCAAGTGGGCAATCGAATTAAATTTGTTATTAAAAGGTAAGATGATAATCTGTAG AAATAGTTTCAGTGTCTTCCCTGAGAAGAGGTTAATTTGATGAAGAAGGGCCTTTTGTTTACCTTATGAC TTATTTCTATTGACAATGAAGGCATTAATATTTAGATTCACTTAGTGAACAAATATTAGTATAAGCATCA GATGTGCAAAATTGGGTCTAACAAGAACACTGTCCTTGGGGCCTTCATACAAAGAAAAATGCACTGAAGG CCGGGCGCGGCAGCTCACGCCTGTAATCGCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTC AGGAGTTCAAGACTAGCCTGGCCAACATGATGAAGCCCCATCTCTAGTAAAAATACAAAAATTAGCTGGA AGCGGTGGTGCAAGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTTGGAGAATCACTTGAACCCTAGAG GCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTC AAAATAATTAAAAAAAAAAAATAGAAAAATGCAATGAAGTGTTATTGAGCGTTTTTAAGGGAGAAGGCAA GGATGGCACACCCAGCTCGGTCACTTGTGCATCCAGAAGAGATGGAAGGTGTTTCAAGTGAAGGAAATCA TATGAGTAGGGGGAGGAGGTGGCAAATATGCCTGCGTATCCACAGAACTCACCCACCGTGTGTGGAGTGA GGACTGCCACGTGGGCGTGGTGGGGTTGCATGGATCGACTTGGGTGGGCAAGTGGAGGAAGGCCTGAGAT CCTACGAACACAGAGGCAGTCACGAAGTGGTCTCGAGGCAGATGCCTCTGAAAATAATGTGGATCCGCCC TTTAGAAAGGTAATTCTGGCTTGATTTTGAAGGATAACACAATGGTTAGTTTGGGTGCGGGGTTAGGAAC AGAAGGCCTCTCTCCACTCATTGACGGGATGTGGAAGGGTAAACCTTCCTTACTGATTGGGGTCATGCCT CTGTGTGTTTGTTGGGACTGAGTTATAAGGGATAGGAAACGTTTAAGATGCTACAGCGAGCTGCTTCTGG CTGTGCTGTGGGACAGTTCATGTAAGATTCAGAAACAGAATTGAGCTGGTTTGGGGGAAAAGTGACTTTC GCCTGTTTATCTTAAATATAGGATGATTTTGAAGGTCTCACCCGAATATCTGAAAATTGCCATTTTCAAA ATAAACTCGTCACCAAAATGATTTTTTTTTCACTATAAAATGAAGGCAGGATGAACCATATTTATAACTA ATTGGCAATGAACAGCTGTGTGAGAAAGGCCTGTGAGTTGCTTCTAAATGCTTTATTACTAATATCAACT CTGTTTCTACAGACCAGAACTTCTGACTCACAGTACCACTGAAGTTACTCAGCCAAGAACGAATACACCA GGTAAACTAGTTGTGAAATCCTTTTTTAAAAACACAGATCAGCCAGGCTCGGTGGCTCACACCTGTAATC CCAGCACTTTAGGAGGCTGAGGCGGGCAGATCACAAGGTCAGGAGATCAAGACCATCCTGGCTAACATGG TGAAACCCCATGTCTACTAAAATACAAAAAAATTAGCCGGGCCTGGTGGCGGGCACCTGTAGTCCCAGCT ACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACGC CATTGTACTCCAGCCTGGGCAGCAGAGCAAGACTCTCTCAGAAAAAAAAAAAAAAAAAAGCACAGATCAA TACTTTGTAAGCTTTTAAAAGTTAATCTTTTAAAATTATGGAAGTCCCCCTTCCCCTGCCTCCCCAAAAA ATCATTTGCAGAAGCTCAATCCAGCCACTCCTTGATTTATCAATGTGAACACCTGCAGTGCACAGATAAC TCAAGCTTTGACCGTAGACCACTGCTATCCATGAGAAAGGCAGTGTGCCCCACAAATGCAAGCCACATGT GTAATCGTCCACGTTCTAGTTCAGCCTGTAATCATTATAAAGAAATACACAGGGAAGTATTTCACGGTCT TTATCCCATGTTCTTTATTTGACAGTTGGCGCGTCTTTCATACTCACAGCATATTTCAGTTCCAAGTAGC CACATTTCAAACATTTCAACTGCTCGGGGATAGTACCTGCTATATGCATTTAGACCTTAATGTTTATTCA TATGTATCGTGTTCCTAAAATGGCAAAGACTGTAACTCTGACCTGCACACAAATATCACAGCCTAATAGG GAAGATCTAAGAAGTCTCTGTTCAATGAATGATGTTATTTTCTTTATTAGAGCTCTAAGTGTGCCTTTAT TTCTTTCCTATCTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGCCTCACTCTGTCATCCAGGCTGGAG TGCAGTGGTGCAATCTCGGCTCACTGGGGCCTCCGCCTCCCGGGTTCAAGCAGCTCTCCCGCCTCAGCCT CCCGAGTAGATGGGACTACAGCTGCACGCCACCACACCTGGGCTAATTTTTGTATTTTTAGTAGAGATGG GGTTTCACCATGTCAGTCTGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCTGCCCTGGCCTCCCA AAGTGTTGGGATTATAGGCATGAGCCACTGCACCTGACCTCTTTCTTTTTGTTTGCCGTTGTGTAATGTC AGAGGAAGTGACCACACTCTGTAGATCATCAGCCACCTTAGGAACTTCTGTTGCCAAGAACCAATAAATG CCCATACCCTGTAGTGTGTAAATGCCCATACCCTGTAGTGTGAAGTTTTCTGTTGTTAGAAATAAGTGTT AGGAATCAAGTATGAAATTTGTGTGTGTACTAGGTGTATACAGATTGGTGCAGTTAATCATGCTCACGAC TACTAAGGTGAACAAATGTTTCAAGTTGGGTTCCTGGGTGTGCCCTAAAATACTTCTCCTTCAGCTCTCA CAGCACCTTGTGGACATGAGTGAAGGTCAGTCAGTGTGCCAAATAGATTTTGTGTGGATTATGGCATGGA AAGTGGCTGAGAAATTCTGTAGCAGGGTAACAAAATTATCTTGGTCCAGGAGTCCTGTAGTGGAGAAGAT AAAAGTCAATGCTTAACTCATAGGTTAACCTCAGCATGCTTTTGATTTGGTCAAGCAATCAAAGTACTGG TGAAGAATTGAAGATTGGAAGTGACACATTTTTTGCTCAGGGAAGTAATGGAGAAAGAAAAATCTTCCTG GAGGTAGATCTTCAGTTTGGATTAGTCTGAACATGATGAAACCTGTAGAAACCTTCATTTCTCAAGACAA AGCTCAAATTCAAGGTTGTGAGGAATGCAGTCACCACTTTTGTTAGGGGCAGTTGTGACAGTGAGTGACT GCAAAAACTGAGAATGCGAAGCCTCTATTGTAAAAAGAATGTGCAAGTGCCATAGAAGTCACTGCAAGGA TTGGGTGCTGGAGCAGTGCCGGACCTGCCATCGTCACCAGAGTGCAGCAGATTCACCAGAAGGAGAATCT CCACTCTTGTCGTCACTAACAGCACTTGACTTTGTCCCATTCATAAAAGATCTTGGAAGGAATTAAAGGT GCTTGGTGGTTCCTCATTCCAACAACACCTTACTTGGCCTGCCCGTGGAACATGCGTTAGTCTTTGGACA GGACAACTCGAGTCACAGACCACAAGAGAAAAGAATTTTGTGGCCATCAGAATTGTCTGCTTAAACACAC CACGGGTGCACAGTGTCCTCAGCTTGGTGAAAGGGAGATGTCACACGCGAGAAGGCAGCGGAGCCAGGCA TGTGATGGAGTGGGAGGTGGCACCTGGCTCTGTGAGGAGGCTGTGAAGTCCTGCATGGGAGGAGCAAGGT GGGGGAGGAGGGGGTGGGGGTGGGGCAGAAGAGGAGGCTGAGCAGTTAATAGAGGCGCTCGACCTTAGAG GAGGAGAGTCCGAGGTCTTTATTGGTAGTATTCAAATGTGGTTCATCCAGAGTTATTTTCTGTGGCTGAA TGGCCTACTCTGAAATCCACAGGGAAAAAACAACTCACATTCAACCCTTGAGATGCTAAGTTTTCTTTTA AAGTAAAGGAAATGTTATAAGATTTTCTGAAACCACCAACCTTTAGCGATATTGTCAGACCTTCTCCAAC ATTTTCCACTGCATTTGTCAGCAATCAGAGATGACCTCCACACCGAGGCGAACCCTCCACCCCCCGACCC GTTTCCTCTTTCTCTCTTTCCCTCCTTTGCTCATCCAGAAACACTTCAGTCATCCTGCATTGTCTCCAAG TTGACCTCCATCCTCATCCGCACCTCGTCCACACCTGAATACTCTGTCCACATCAGTGATATTCTACATG TCTTTATAATAGCTTTTTTGTTTGTTTGTTTGTTTTTTAAATTTTGATGCTTAAAAGGCAATGGTTGTCT TAGGGATAGGAAAACACACCCCACTGTCACTGTGAGTGAAGCTGAATAACGTCTCTAGGTCTTTTACCAT TGCTTTCTTTTTTTTCTGAAGTGATTTTTCCTTTTATGTCCATTGCTTTAAGCCATTTGTGAAATTGCAC AGTGATTTCTGGAGTGGGGACAGAAGGAAGGCGGTAGTAAAAGTCATTGGTGCTGTGGCCCAGTTGGCTG GAGGAGGTGCAGGGCAGGGCGGCCTGCGCTGGGGCAGCTGGAGGAGCACAGATGTCCCCACGGGCAGGTG GATGAGTTCTGAGAGCTGGAGGGCCGGTACAGTGTCCTCCATGGTTCCAGCTTGTGGGCTTGATCAGGCC GTCACCTGCGGTGGCCACTGAGCTGGCGATGAACTCCGTGGCCTTGGAGTCGCCCTCGGCAGAGATGATG GCCGCCGTCTTCTGCTGCTCAGCCCTTGCCACCACAGATCTGGCCCTCTCTTCTTCCTGCTGAGCCACCT CTTTGGTTCCACTGCTTCTGCAAATTCCTTCCCGAAGGTCAGATCCAAGGTCACAGCATCCAGGAGGAGC CCAAAGGTTGCTGCTTGCTCCGAAGTTAATTGCTCACCTGTCTGGAGCCCAGCTCTCCCTGCGTGATCAG TTCTCCAGCGTCAGCCTGAGCCGCCCCCAGCTTGAGGAGCTCCGCAGTGATGGATGGCAGCACATTCTTC ATTGGCTTCTCCAGTAATTGGAAGATGCAAGGACCTGGCCAGCAACAAGGTGGGAAGAGGACGCCCAGTG TGATGGTGACAATCTTTGCTCACAGTGATGATTGGTGCATAATGTGGTCAAGAGCAGCAGTCAAAAATAA TTGGTTTCTTTTCCCATGGGATGAGAAAGTGCGTTCCTTCCCCTATCACAGTGTCCTGAATGCCATGGAA TTGGTCGAAGATGACAGACAGCTCTCTGTGCAGCATCACATTGTAGAAGGCAGAGTTCCCCACACCTCCT GCAGAAGCTAAGGACAGGGCAGACTTGGCAGCTGTGTTTCCATCTGCTGGACCCACTCACGCCTGCGTCC ACTCCAACCCCCCACATGAATTCCGTCCCTTTATCATTGATTTCTGATGCGAAAAGTCACTTTGATTAGT GAAGTGTTGCTTTATGTAGATTTTTAGGCACACATCTGTTAGATAAAACGAGGATTGCCTGTAGAGAAAG CAAATAAAAGCAAAGTCCCTCTTGTTGAAACTGGTGTGGGAGCCCTTGAACCTCATGCAGCTGGCCTCCC TGCTCTGACCGAGTTCCCTGAGGGACTTCTCCAAGGAGGAATGTGTGAGAAGCACTGATTTTGAGCACTC TTTCATGTGGACAAATTTCACTTTATTTACAATGTAAACTTAAATTTAAATTCTGTCTTTCTAGGCTGGG CACGGTGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGCGGGCAGATCACTTGAGGTCAGGCA TTCAAGACCAGCTTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATATAAAAATTAGCCGGGCGTGG TGGCGGCTACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGA GGTTGCTGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCGTCATAGCAAGACTCTTTCTCTAAAT AAATAAATTAATTCTGTCTTTCTGCAGTTTTTCTGATATTTGGCAAGTACTGGAAATTATTATTTTCCTT AAGACCCCAAATTTTCACACCAACATGGCACATGTATACATATGTAACAAACCTGCACGTTGTGCACATG TACCCTAGAACTTAAAGTATGATAAAAAATAAATAAATTAATTAATTTAAAAAAAAAGACCCCAAATGTT TGCTTTTAACAAAACTGAATTAAGAGAATCACTGCAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAG CACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAGGAGATCAAGACCTTCCTGGCTAACACCGTGAA ACCCCATCTCTACTAAAAATACAAAAAGAAATTAGCTGGGCATGGTGGCGGGTGCCTGTAGTCCCAGCTA CTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGCGAAGCTTGCAGTGAGCCGAGATCGCGCC ACTGCGCTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAAAATAAAACAAAACAAACAAAAAAGA ATCACTGCAAACAAGAGTACTTTCTAGCAAAATCCATTCTGATTTGCAACAGCACTGATAAATAACATGG TTATTGGGTTTCTTTTTGTTTTCCAGTCAAAGAAGATTGGAATGTCAGAATTACCAAGCTACGGAAGCAA GTGGAAGAGATTTTTAATTTGAAATTTGGTAAGTAAAAGCCAGTATTTATGTCTTTAATAACATATCAAC AAAGGGCCATGTCTGAATGAAGTATAGAAGTTCGGGACCAGCCGGGTGCAGTGGCTCACGCCTGTAATCG CAGCACTTTGGGAGGCCAAGGCGGGCGGATCAGGAGGTCAGGAGATCGAGACCATCCTGGCGAACACGAT GAAACCCCGTCTCTACTAAAAATACAGGAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCT ACTCGGGAGGCTGAGGCAGGGGAATGGCTTGAACCCCAGAGGCGGAGCTTGCAGTGAGCCAAAATCGCAC CACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAGAAGGAAAAAAAG TTCAGGACCTAAAGAAGGAAGGTCCCAGAAACTGGGTTTCTGTTTCTTTCTACCACTACACTTGCTACTG AAACCAAGCAGATGACTTCATTTCTCTTGGATTCCACTTTCTCACGTGTCAGAATGGGAGAGGAAGGGAG GTGTTGGGATAAGTTTCAGTTCCACTGTTTGTACTTCTCGTCTGGCTAACACCCATGTGGCAAATAGGTT TCATCATTTGTTTCAGCTTAGATTTGTTGACAGCGGTTTCCTGGAGTGCTGTCTTGAGAACGATTCTGAG GAGGCTCAGCAAGAAAGAGTGTTTCAGTTGATTGGGTGTGTCTGTCATGGAGAAGGAAGTAAGGAGTGGG CAGTGCTAGCAAAATTCCCGGGGCACTTCTGTCCATTATCTCAATACCTGGGGTTGACATTTCCTGTCTC AGATCAGGAGTCCTGACTACCCTGCCTCTGACCACTCGAACTGAGTGCTGCTTAGCTGTATCGTAGACAC CGCCTGTTTGTGAACAGACACCCTGCTTCTTGATGATAACACAAAGGCCAGCAGGGTCCACTGCTGTGTG GAATGGCCTTCGGTCATTTCTGCCCAGAGCATAGAGGTCATTTTCACTAATAACATAACTCTCCTTTTGA TTGAAAGTGTTAAAATGTTCCTCCTAAAAGCACTTATTTTTTAGGCTCGTTCTTCAGATTTGCCCCATAT CCTAAGCAAAATGCCTTCAATATGAAGTGGATATTGCTTGACCGTAGGGAGCTTGTCCATACTGTACTCG AGAATGTAGACACAAAGAAAGAATGTCTGTGTCAAATGTTATCCTCCGCAACTTAACGTTCTCTTGCACT TTCAGCTCAAGCTCTTGGACTCACCGAGGCAGTAAAAGTACCATATCCTGTGTTTGAATCAAACCCGGAG TTCTTGTATGTGGAAGGCTTGCCAGAGGGGATTCCCTTCCGAAGCCCTACCTGGTTTGGAATTCCACGAC TTGAAAGGATCGTCCGCGGGAGTAATAAAATCAAGTTCGTTGTTAAAAAGTAAGTTCTTTTTGCCACTGT AGTCGTTTCTGGAATCAAAACAATAAAATGACATTTCTGTTAAGATGTTTTTCAAGCTAGAGGTGACAGG CGTGGCTGTAAGTCCTTGATGGCAAAGCCTGGCTGTGAGCTGCAGTCCGGGTACTGTCCATTGCCCCTGC CCATACTCAATCATCTTCATCCGTGCAAGGAAAATAGTGACAATCGCCTCCGCGGAGTCACCGTGAGGCC CCGTGGTGACTCGCAGTATGCCTGAGTACTTGAATGGAAGTTTAATTTGCTGGTTTTTATCTGCTCTGTT ATTCCTGGTCAATCTTGAGAGCGACTAAATATTGATGATTGAGTTTCTTTCTTTTTTTTGAGACGGACTC TTGCTCTGTCGCCCAGGCTTGAGTGCGGTGGCGCAATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTC GAGCAATTCTCGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGACTTGCACCGCCACGCCTGGCTAATT TTTGTATTTTTAGAATAGATGGAGCTTCACCGTGTTGGCTAGGCTGGTCTGGAATTCCTGACCTCAGGTG ATCCACCCGCCTCAGCCTCCCAGAATGCTGGGATTACAGGCATGAGCCACCGTGCACGGCCTAATGATTG ATTTTCTTATCTACATTTCTGCAGAATTTTAGTGGCTAAAGAAAGTACACTAGTGTTTTTTTTTTCTTTT TTAATGAAAATAGTCACTTATTTACTCTTCATAAAATGGCTTACCAGTCATGGGAAGGAAAAGTCAGGGT CTTTTGTCCACAACACTAGGAATTATTGTGTTACAGGATGATTCTGTGAATGCCTTTAGAAAAAAAACCC TGATCACATCACGACCGTTTTACTAGCTGTGAGGCCACCACTGTGCTGGCTACTGTAACACTTCTTGGTT TTCTTTCTAGACCTGAACTAGTTATTTCCTACTTGCCTCCTGGGATGGCTAGTAAAATAAACACTAAAGG TAAGAGACGACGTGTACTCCGTATCCTATTTGAGCGCATTAAGACACTCTTTATCCGCATTCCTTAAATC ATACGGAATCGGCCAATATCTCTGTGGGGCTTGGAGTTGTTTACTTTGCTTTCTAAGGTATTTTATTTAA TGGAACTATTTTTCTTTTTTTTTTTTAAAAAAACAAAACATTTCATTGGAAATGTCACATTTGCAATCCC AGTTCATTCATGTTTTCACAGCTTTGTTGAGCCCCTGTGGAGGATTACACTACAAGTTTAATTCTGCAGG TTTCTTTGAAAAGAACCAAACTGTATGAATTTTAATACTCTGCTCTTATAAAGCATCTCCTTCTGTATTT TTTTTTCCCTACAATATACAAAAGGAACTCTGCTTATTTTACAGCTTTGCAGTCCCCCAAAAGACCACGA AGTCCTGGGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGTAAGGGCCAGTCCTCGGTAT GTTTCTGTTCATTCTCTAGTTTACTAATTATGTCAGTTCACTAGCTATGTGTTTATACAGGTTTATACAG ATGACGTTAACCAAACTAGCTTTTAACTGTGAACAGCTGCCTGTGATAAAGCTAAATTTCTGAATGCTTC TAATTGAAAATTTTTAAATCCTTAATAGAAAACAGATAACATGGATCACATCATAAACTTCCCCCAAGAA AAGTCCTAAAATGCTTTTCCTTTATCATAACAAATAAGGGTGCAGAGTCATGTGGAATGTTTTATCTTTT TTTTCCTCTTCATTTTTTTCTATTGTTTTAAGGAAAGAAAGTTTAGGGTGGTTTAAACAGCAGTGCCTTG AATAAAAGTATTTTCTTTTTCTTTTTTGAGACAGAGTCTGGCTCTCTTGCCCAGGGTGGAGTGCAGTGGC ACAATCTCGGCTCACTGCAGCCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAGGTAG CTGGGATTACAGGCGTCCACCACCAACTCCAGCTAATTTTTATATCTTTAGTAGAGACGGGGTTTTACCA CGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGAGCCACCACGCCCAGCTGGTTCTTGTCTTTTC AGGCTCACAGTGTTAAAATACTGCATACAATACTAAAGACAATCTCCAACCAACTGTCAAGTATGGATAT TTCTTCCATCTCTTCATAAATGCAGAAGGAAATCACTGCATTAGGATCATTCTCTACATCCCAGGTGTCA AGTTTTTAAATAAGAGTTTGCCGTACTGGTGTTGAGTGGCGCAGAAGTCCCTATTTAGTCATGTGGCACA CTTTCAGAGAGCCTGCTTTCTCATAAGATAGCCAACAAGCATCCATGGACAACTTACACCTGATTAATTA TTTCTGTTCAAAAATGCCAAGAATTAAAAATATATTGAACCCTTGACTTTCCTCCTTCCGGAAGAGATCA GAGGAAGATCTCTCTTATATACAAGATGCCAGCCTTTCCTAAAGGGCAGAGCCAAGTTCACGGGGCCTGG GAGGCCTGCTTTAAGAATACAAAATTAGGGCCAGGCGTGGAGGCTCACGCCTGTAATCCCAGCACTTTGG GAGGCCGAGGCAGGCGGATCACCTGAGGTTGGGAGATCGAGACCAGCCTGACCAACATGGAGAAACCCCA TCTCTACTGAAAATACAAAATTATCTGGGCCTGGTGGCGCATGCCTGTAATCCCAGCTACTCAGGAGGCT GAGGCAAGACAATCGCTTGAAACCAGGAGGCAGAGGTTGTGGTGAGCCGAGATTGCGCCATTGCACTCCA GCCTGGGCAACAAGAGCGAAACTTTGTCTCAAAAAAAAAAAAAAAAAAGAAGAAGAAGAAGAAGAGAAGA AAAATGGGTTTCTGTAGAAATAGAAAAATGGTTTCTGTGGAACTCGCCGGAATGACAAGAATACCCATTT CAATTTGAACCTAGCTTTGTTTTCTGGCACAGGCTGGACTTGAAGATTGTAACCTAGAGACACTTACGTC ATTAAATGTGTGTTGATTATCATTATTTTTTCTGTCTTTTAGGCCCTAATAACAACAATCCTCAAACCTC AGCTGTTCGAACCCCGACCCAGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCC TTTGGTAAGTAAGCGTTTTATTTTTCTTTCTTTCATAGTTTTAAATAGAATACGTTCATTATGTTTCATT TTACCAGGTGAATTGTTCCTATTGGTGAGTCAGTATATATCAAAGGTTAAAGGAATAGCCCGTAGAGCCA GGCTGCCTGAGTTCAGATCTGAGTTCAAATCCGATGCCACTTGGGCAGGCGAATACACCCTGCCTCAGTT TCCCTTTGTGCAAAATGGTAATAACATTACTTTCTTTCTCATGAGGTTATGGTGAGGATTATAAATACTG TCATTTAAAGTACTTAGAACCATACCTCGCATGTAGTAGAGACTATAATTTGTGGGGGCATTTTGGGGGT TTTCATTTGTTTTTTCTTTATTTTAGCATTTGTTCACTTATTTGTAGTCAACATAAAAGCAATGTACTAA AACAGTTTGCTTATGTATCAGGATGGGAGTAGTTGTCAAGTCATATCATGGTAAAAGATTATGCATTTTT TATTTCTTCTTAAAGATGCACAAATAAGGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAACACTTTGGG AGGCCGAGGTGGGCGGATCACCTGAGGTTGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGT GTCTACCAAAAATACAAAATTAGCCAGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTCAGGAGGCTG AGGCAGGAGAACTGCTTGAACTCAGGAGGTGGAGGTTGCAGTGAGCAGAGATCGCACCATTGCCCTCCAG CCTGGGTAACAAGAGCGAAACTCTGTCTCAACAAAAAAAAAATAAGATGCACAAATAAGATGAAACACTC CTGCCTGTGAATGTGTATTGATAAGTACTGTGATAAGTATTGCAATTTAACTCTCTTATGTTTTATATGC AGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAAAGTTGAAAATCTCTTCAATGAGAAATGTGGT AAGTCTATTTTGAAACCTTCTTACTGCCACGCAGGGTGCCTTCATGGGAGTAGGAGGGAGCAGAGTGGGA TACTGAGCGTTGGAGTATCCCTGTCATTGGCAACGTGTGGGTTTTTCGGGATTGAATGGCGTCATTTCGC CCATGTTCTGTTTCGTGTACGCGGCTGTTTTGCAGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTG CCGTTCGCGTTATTTGAGTCTTTCCCGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCC GAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAGAAACAAAGCCAAAATTAAGTTCAT CATTAAAAAGTAAGGAAACTGGATGAAGTGGGATTAGCATGAGTTGATTGTGTTTGACACTGGGAGATGG GTATGTGGGTTTGTGTTTGTGGCAGGGCTGAATTAGCTCTGGAGTCAGAAAAACTGCTTTTTAAGCTGCA CTCTTGTATATGTTTAAAACTTCTGGCCAGGTGCGATGGCTCACACCTGTAATCCCAGCACTTTGGGAGG CCAAAGCAGGTGGATTACCTGAGGTCAGAAGTTCAAGACCAACCTGGCCAACATGATGAAACCCATCTCT ACTAAAAGTACAAAAATTAGCTGGGCGTGGTGGCACGTGCCTGTAATCCCAGCTACTTGGGAGACTGAGG CAGGAGAATCACTTGAACCCAGCAGGCAGAGGTTGCAATGAGCCAAGATCGTGCCACTGCACTCCAGCCT GGGCAGCAAGAGCAAAACTCCATCTCAAAAACAAAAAAAAAAAAAAAAAAGAAGAAGAAATTTTCCTTAT GCTGCTGGTAGAAGGGAAGGAGGACTCCACCATACTAGAGAGATAACGACTTTTGGTTGCTAAATCTACA CAGCTATGTTGTTACTATTTGATGCTGCTGGAATCTGAGCAGCTGTTTAGTTTTTCAAGTCCTTTTATTT CTCCAACTTAATAGAATATTTTCAATTTCTCCTGTTTGCTTGAACATCTGTGGATTAGGCTAACATAATT GAAATAGATAGGAATGGGCCGGGTGCGGCCATAAATCCCAGCACTGTGGGAGGCTAAGGCAGGCAGATCA CTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAGCCCCATCTCTACTTAAAATACAAAAA AAAAAAAAAAAAATAGCCAGGGGTGGTAGCTGGCACCTATAATCTCAGCTACTCAGGGAGGCTGAGACAG GAGAATCACTTGAACCCAGGAGGCGGAGGAGATCGTGCCATTGCACTCCAGCCTGGATGACAGAGTAAGA CTCTGTCTCAAAAAAAATTAAAAAAAGAAATAAGAATAATTGGAATTTTATAGTACATGCTAATGCACAT GAATTATTTGAAATCAATTGAAATGAATTTTAGGTTTCATTTGCTTGGTGTCAGGCTTAATTTTGAGTCA CCCAGGGATGCTCTCAAGCAAAGCTGGCCACTTTTTTTTTTTTTTTTTTTTTTTTTTTTGTGAGACAGAA TCTCGCTCTGTACCCAAGACTGGAGTGCAGTGGTGTGTGATATCGGCTTACTGCAAATTCCGCCTCCTGG GTTCAAGCGATTCTCCTGCCTCAGCCTCCAAAGTAGCTGGGATTACAGGCATGTGCCACCATGCCCAGCT AATTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCATGTTGGTCAGGCTAGTCTCAAACCCCTGACCTCA TGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAATGGCC ACCTTTTATGCTTTTGGCCAGGTCTGCAGAGGTTTGGCAGCCTCTAAGCCCTCTGCTTCTGCTTCCGGAG TGAGAGCCTCAAGTGCTCCTGTTTTCACAGCCCATCTTGTGTTTCCATGCTGCGTTTGTGGGGCGTTTTC TCTTTGCATCCTCAATTCTGGCGCTGATTCTTTTCAGGATACATTCTAACCTTGGAAAGAAGATGCCAAT AAAACCAGTGTAGGGGAAGGGCAGCCAATGAGAGGCAGCAATGGATGTTAAATTTACAATTGTGGTTTGT CTTTTTGGCTGTGGTTCTTTAGATAAGCATGTGATTTCTGTTCTTCATGACTAAGAATTGAATTTAGACT TTACAGAGTTACTGGTTTGTAAATCTTTGAGTTGTTTAAATTTTAATGTTAGAGTTTTACTGTTTGATCA GCACATTTTTTTTCTCTTTTGTCTATAGGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTC TAAGAGCCCTCCCAGTGAGTGTATTTTCTGTATTTTCATTGCTATAGAACACACGCTCTTAGGCATGCAT TGTGCAGCTGTGGTTTACAAACATTGTTTAAAGAATAGCCATTGAGGCCAGGCATGGTGGTTCACGCCTG TAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCC AACACGGCAAAACCCTGTCTCTACTAAAAATATAAAAAATTAGCCAGGCGTGGTGGCAGGCGCCTATAAT CCCAGCTACTCAGGAGGCTGAGACAGCAGAATCACTTGAACCCGGGAGGCGGAAGTTGCAGTGAGCCGAG ATCGCACCACTGCACTCCAGCCTGGACAACAGAGCAAGACTCATCTCAAAAAGAAAAAAGAAAACCCATT CAAAGTTGTAGTTCAGGCTATTTCACAATTTTTAGTTATTTAATAATTGGGTGGCTCTGTGAGTGTGTGA TGATCTCCTAAGTACCCCCAGGAAGAGAAAAACAGTGAAAGGCAGCCCTTCAGGGGGCATCATGTCTTCT TGAAATGATCTACCATGGAAAGAAAGAACCTTGAACAGGACTGAGATAAAACAGTCTCAGACAGCATGAT TATTAGAGATGTTGACCGTGTTTTCTACAAATTCTGATTTTAAATGTATATTTTCAGGAAAAATAAATTC ATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGGT ATGAGTTCTCTGCTTCCATCAGAGTTTTTGGGGGTCTCTTCAGGGCCTCTTGGACTTTCCCAACTAGAGA GGTTTGCTCAGCTCATCCGGGGACTCGGATACATTACACGTTGCCTGGTGCTCCTCCCAGACTCCTACAG CAGTTGCCTTCCAAATACAGTTGCTCTCCAAACAGCAACGGCAAGTTTTGGCACTTGGCATGAGCTAAAT CCTGTTAACCACCCAAATGGCTAGTCTGTTCCTTAAAAAAAGTCTATATGAGACCGGGCACGGTGGCTCA CGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATCGCTTGAGGTCAGGAATTCAAAACCAGC CTAGCCAACGTGGTGAAACCCTGACTCTACTAAACATACAAGAAAAATTAGCCAGGCCTGGTTGTGTGTG GCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAAGTGCTTGAACCCGGGAGGTGGAGGTCGCAGT GAGCCGAGATGGGGCCAGTGCACTCCAGCCTTGGTGACAGAGCCATACTCCATCTGGGAAAAAAAAAAAA TCTATATAAAACAGCAGGTAAAGGTCTTTATAACAAGAATAAATTTGTAGCATTTTTAGTTAGGCATTAT TTTAAACAATTTCAAATTTAATTAGCTCAAAGTGCTCAAATACTTAAATCATTAAAAAATGGAAAATGCT TGAAAACATTACACAGAGCTCCTAAAAATTGGGATTAAAAGTGCATCATTGAGCAGCGGCTTGTACCTGT AGTCTCGGCTACTTGGGAGGCTTAGGCAGGAGGATCGCTTGAGCCCAAGAGTTCAAGGCCAGTCTGGGCA ACATCGTGAGATACCATCTCTTTACCATAAAAAAAAAAAAAAGCAGTATTTAAGTTTTGGGTTTTCTCTG AACTGTTTCAGATGATGATAATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTG AATGACCTCTTTAGTCGGAAATTTGGTAAGTTTTGCATTTGCAAAGTACAGTTGCTATAAGCAAAGAGAT TTGTTTTAATAAGATCTTTTCAGCAGATGATGGTTGGATGGTTGTAATCCTATATAAAAGGAGTTAAAAT TTAAAAGTGAGTTGTTTGTGCTAAATTTATTTAATAAGATACCATTAGTGTTACACTATTGATTGTCAGT ATGAAAGTTAATGAATTTAAGGTTCACCATCTGGCAGTGTGGCTCACACTTGTAATCCCAGCACTTTGGG AGCCCGAGGCAGGTGGATCAGTTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAACCCTGT CTCTACTAAAAAATTCAAAAAATTAGCCGGGTATGGTGGTGCACACCTGTAATCCCAGCTACTCAGGAGG CTGTGGCACGAGAATTGCTTGAACCTGGGAGGCAGAGATTGCAGTGAGCTGAGATCAAGCCACCACACTC CAACCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAATTTAAGGTTCATATTTAAATTTGTT TGAAGTGTACAAAGACCTTAGTTAACAGCAGAGACAGTCTTTAAAATAAATGTTGATCTTGTGCTTTTGA CAGGCTGTTTAAGGCGGTGGGTTAATCTGTGCTGTTGTGCTGTTTGTCTCACTGTCCCTGTAGGTGAAGC TATTGGTATGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTAGTT GATGGCATGCCCCCGGGGGTGTCCTTCAAAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCT TAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGGTAAGTGAGAGTTTCCTGCTTAGTCACAGGAGC GAATCTGGAGCTCATGAGGCTGACTCTTCTAAAATGCAGCCACAGGTAGTCATCGAATCCGGCTTCCTAT GCTGTGCAATCAACAAATCAAAATAACTTGTGTCATCATTAGAATGTCAGATGTGCTTCTACGAACTAAG CTGACTCTTTTAATTCTTTGGCAAAGGGTTGGCAAACTAGGACTGTTTGCCAAATTCAGGCTGCCTCCTA TTTTTAGAGTCTTCCTGAAACACAGCTACACCCGTATTATCCATGGCTGCTTTCCTGTCACAGTGAGTAA GTAGCTGGGACTGAGAAGGCATGGCCTCCAAAGTCTAAAATATTTACTCTCTAGCACTTTGTAGAAAAAC CTTAGCTAGGCACAGTGGCTAACGCCTGTAATCCCAGCATTTTGGGAGGCCAAGGCAGGCAGATCACCTG AGGTCAGGAGTTCCAGACCAGCCTGGCCAACATGGTGAAATCCCATCTCTACAAAAATAAAACAGTTAGC TGGGCATGATGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATAGTCGCTTGAACCCA GGAGGTGGAGGTTGCAATGAGCCAAGATCATGCCACTGCACTCCAGCCTGGACGACAGAGTGAGACTCCA TCACAAGAAAAAAAGAACTTTGTCAACCTCTGTCTTAGGGCGCCTTGTCACAGGCTTCGGGTCAGACGGA TTCAACCTTGCATCAGCCATTTGTTAGCCAGGTCACTCTGTTCTTTGTCTGTAAATGAGATTGATCGTTG TTCCCACTGAGAGTGTCAGCTCCTTCCCGTAGAGCAGGCATGATGATTGTACTCACCTCTGACACCATTG TGAGTGCCACATTCCTTCCCACGTCCTTGTCACTGTAAGAGATGCCCACCTGAGCACCAACCCCAGGTTA TCTTCCCCTTTGTCTTCCAGCCCCCCAGAAACAGCTACGACTCAACCTACCCAATCATTTCATCATCAGA TTGCCACTGTCTCTAGTTCAGGTCTCTTGGAACTGGCACTCAGAAATCTCATAATAAATCCTCTTGAGGC TTCTCATACACTCGTCTTCTTCCAATCTTCTTTCCCTCAAAATCTCATATTTTGGTTCCACTTCACCCAC CGTCATTCTCCATATCACTCCCAGGAGTTAGGCAAAAAGCCCCTTCCGTTCTTCCGTATGTTAAACTTAG AATCACTCTGTTCCCTGCTCTGCGTTTCTATTTTTTGTTTTTCCTCCATTTACTAGTAGCTTAACACTTT CTAACAGTGTTCTTATTATTGATACGTATCTATCTCTTCCATAAGCTTATAAGGTCACGGATAATACTTC TCATTGTAGTACGTAAATGACGTGGGCTAGATATGAGTTGAATAAACAGTTATACCTGTAAATTCTTACA GAGTGAAAATAAATTGTTATACTTTACAATTTGTTTCTCTCTTTAGACCATTTCCAGGACTTGTGATTAA TAACCGTGAGTATTTTGTGAAGTGTTTTGTTTTTGTTTTTTCCTGGGGTCTGACGTGTGTGCGTGTGAGT GTGTATACATGCTTAACGTATATCACGTTACTTCACCTATGTCAGTAACCAGGCCAAATACTTGTTTTAG CCCTCAGTAAAAACACCAGGCACTTCCTAGTTGTAAAATTATTCAAGCTTCTTAACTTCCTATCCTCGAT GCACTTAATCATAAAATGGTAATAATAGCACCGATTTTGGGGGAGTCGTTCCAGTAGATGGAAAGCATCT GGAACAGGTGTCAGCAAGCTCCTGCCGACGTGTATGCATAAAGTTTTATTGAAACCACCATCGTGTCCAT TTGTTTATGGCAGAACTGAGAGATGGCAGCAGCAAGTGTGTGCCTGCAAAACCTAAAATATTTACTAATT GGCTCTGCAAGAAAAGAGTTTGCATCCCCCTAACCTAGAACAGTGTCTAGCCTCTAGTATGTGTTTAGCC TACAGTATGTGCTCAGCGAATACAATCTATATTTATTACTGCTTTTATGACTGTTATAATTACTGTGCTT GGATTTCGTTACAAAGTAAGTCACAATGTGCCTGCTTCTGTTAGTATTTCAGCACAGTGCCTGGCACACA TGGGGCTCTCAAATATTGCTGAGCGAGTGAACAAATGTCCTTTCAATTCCTTAACGTTGATGTCATTTTC AATAGTATTTTGAGCCAAACTTAATTTTGCGAGTGTGTTTTGTTTTCTTAACTTTATTATTAAAAATGTA TAAAAGTGAGGCCAGGCGTGGTGGCTCACGCCTGTAATCCCAGCAGTTTGGGAGGCTGAGGCAGGCGGAT CAGTTGAGGTTGGGAGTTGGAGACCAGCCCGTCCAACATGGTGAAAGCCTGTCTCTACTAAAAATACAAA AATCAGCTGGGTGTGGTGGCACGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAGTTGCTT GAATCCTAGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCA AAACTCTGTCCCAATAAATAAATAAATAAAATGTTCTCTTTTGTTCCTGTTCTTGTGCGGTAGTGTGGTA TAGAGTTTTATGGTAATTACTGTGAATTAGTGATTCTGAGGGACATATCAGAACTCTGAGGTTTGTTTCC TTCTCATCTTGAGGGAAACAGCAAATGTATGTTAAAATGCTTTTCCAAGGGAACAACACATCCTTACATT ATTTAAACCAATCTGCTTCATTTTCAGAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGG TGAGCGAGGCAGGGGAGGGCCCGGAGCTACTCCTGCCTGCACAGTGGCACAATGGCGTGCCTGCGTGTGG CTTTGGCTCTCAGTCACCTGCCCTGAGGGGACTCAGTTACACAGCACACACATGCTTCTCTGTGGTTTTC ACTCCTGGGTTTGACAGCTGATCAAAACATAAATTCAAGCTGTGGGTCCTGATTGAGAACTGGGGGCTGC AGACCATTTGCACCCCCTATCCCAGCTCAGGCCTAACATCAGGAACCCCAGGATTAATGGGTAGGATGAA ATGGCAGAGCAAGAGGGCCGTCACTTTAACCTGACTCTGCCATCCATTTCTAATGTCTGCCATAAGTCAG TGAGCAAAATGTTCTTCAGTAGAAATGTACACATTGTGCTCTTAAAAAATTCCTTAAAAAACAAGTGGAA TGGCCTGGTGCTGTGTGAGTCATTGAAAGTAATGAGACTGGGCGCGGTGGCTCACGCCTGTTATCCCAGC ACTTTGGAAGGCTGAGAAGGGTAGATCACTTGAGATCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGC AACCCCGTCTCTACTAAGAATACAAAAACTAGCCAGACGTGGTGGCGTGTGCCGGCTACTCAGGAGGCTG AGGCAGGAGAACCGCTTGAGCCTGGGAGGCGGAGGTCGCAGTGAGCCAAGATCGTGCCACTGCACTCCAG CCTGGGCAACAGAAAGGAGATTCTGTCTCAAAAAAACAAACATACGAAGAAAAACAAAAAAAGTAATGAA AAGCTTTTATTAAAGGGAGTAAACAGAAGGATAAGGGAGAAAGCATAACTAAGGAGCTTGTTTTCATGGT AGAGCTATGTTAAGACTCTGCTCTTTCAAACTTCAGTTGCATATGTGAACTTAGGACCACATTTGAAAAA CAGAAATTTGAAAGTACACTTGGATAATCGTGTGCTCCATCTCAAGACCGTGAGCATTGTTTCATCATGC ACCTGTGTTTGTACAGAGTCTAGAGGGCTTTTCTCCTCTTCCTCCTCCTGGGTTCTTTACATAGTATAAA GCAGCTGTTGAACAATGTGGAAATCAGTCTCTGTGTTTCTCTTTAGAATCAGCTGAACCAAGCCAGTTGG AAGTTCCAGCCACAGAAGGTAAAAGGGTGGGGTGGTCCTGCAAGTCCTTAAGACTTCTTCTTTCTTCTTC TTCTTTTTTTTTTTTTTAAAGACAGAGACTTGCTCTGTCACCCAGGGTGGAGTGAGGTTGCGCGATCTCT GCAACCTCCGCCTCCCGGGCTCAAGCAGTTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCCT GCACCACCATGCTTGGCTAATTTTTGTATTTTTAGTAGAAACGGGGTTTCACCATGTTGGCCAGGCTAGT CTCAGACTTCTGACCTCAAGTGATCCGCCAGCCTTGGCCTCCAAAGTGCTCGGATTACAGGCGCGAGCCA CCTTGCCCAGCCAAGACTTTTTTATCAGGACAAAGGATTGTGCATTTAAACTATTTCACTAGAACTGGGT GGTGGTTTTGCTCTCTTTCTTCTGGGTGAATTGGATTTGCAGGTTATGCTGTTGAGTGATGACGCATAGC TGCTTTTGCTCCATTTCCCCCAGATGACTTGGTAAATTCTCCGTGAATGACTCTGCTACATAACCTAGAT AACCTAACGTGTGTCCTTTAAATGCATGTAAGCCAGAAGATGTATGTTACTTTGAAAACATAAGTAACAA AATTTTGAATGTATTGCTAAAGAGATGTCTCTCTGAAGCTCTTTTGATGTTTGGTGTCTTGTCCTTCTTA TTAAACCATATCTTAGTAAATAGTTTGGTACGAATGGATTTATCACTGAGCAGGTCTGCAAAATAATTAA TCGGTACCGTTTTGTTTCTGTTGATAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACC AGACCCCACGTGGTAGACCTCTTCCCTCCTAGGGTAAATCAGCTTCTGTGTCAGGGATGCTGTGTGGTGT CCATCTGAACCCCCTGCATACGCGTAGCTAATGTGATCTCCCCACTTTCACATAAGATGGTGGCCCTGCC TTCAGGGAATGTGGGAGCCAGGTGGGAGCCTTCCCGGATATTTAAGCTAGAAGATTCTACAGGGAGATTC TCCTTGGATCAATATATGTCTCTCAGTCAAAGATGTAAAAGCACTTTTGCCTTAAAAAGAATGTTCTGTT TCTAAATAGAGTCAACGTTGTCCTCCTCATTGGAATTCACTATGAGTCAGAATCATTAGACTGACTTTTT TTTTTCCATAGTAATAGTATTTTGCAGAGTCTCACAGAGCTGCAGATCTTTTGTTCATCTTGCAGAGTTA ACAAGTCTGATCCTGTTAGTCCAGATTTCTTAAATTTGGCCAAGTTATAATAGGAGCAGTAGCTTGAGAC CCGAAGTCAGGAAACTTTGACAATGGATTTTTTTTTTTAATCCAGAGACTTGTACTGGAATTTGCCTTAC CCTGTCAGCTCATGGACTTAAGGTTTCATCCCGCTTTATGAGTGCTTCTGAATCCAAGTCATTGTTACCT GAATTTGCAAATTAAGTTGTGATATTCGTGACTGTTAAATTCCTGTAATTAGATTAACCTCTTTGCTTGC TTGTTTGTTTTCTCTCCTATTTTAGCTTAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTA CCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAAACCTTTTTTTCTACTTTTAGAT AGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTGGT GTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAA TCTCACCAGATTTTTTATGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGAT ATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGCAGTGAAGAAAAATTCCTGTGATAGTTCAGTTC TTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCTCCTTAATGACTG AGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTT TTTATCATAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAAT TATAGAGGAAATACAGAGAGAACCTCTTCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAG AAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGGCCCCAACATCGCGGGACCTGCT GTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTATT TCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCA ACCTCTGACGTTCTGCGCCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGT AAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGGCATAGTTTTCAGTAGCTTTATCACAATATTCA CAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTATTTTACCTCAAAT TGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA bcftools-1.21/test/csq/ENST00000573035-bt2212/ENST00000573035-bt2212.fa.fai000066400000000000000000000000211467060157400233520ustar00rootroot000000000000007 49960 18 70 71 bcftools-1.21/test/csq/ENST00000573035-bt2212/ENST00000573035-bt2212.gff000066400000000000000000000005621467060157400230020ustar00rootroot000000000000007 ensembl_havana gene 100 49960 . + . ID=gene:ENSG00000263001;Name=GTF2I;biotype=protein_coding 7 ensembl_havana mRNA 100 49960 . + . ID=transcript:ENST00000573035;Parent=gene:ENSG00000263001;Name=GTF2I-212;biotype=protein_coding 7 ensembl_havana CDS 300 377 . + 2 Parent=transcript:ENST00000573035 7 ensembl_havana CDS 4125 4184 . + 2 Parent=transcript:ENST00000573035 bcftools-1.21/test/csq/ENST00000573035-bt2212/complex-event.txt000066400000000000000000000002251467060157400231070ustar00rootroot00000000000000374 CAAG CT frameshift&splice_region|GTF2I|ENST00000573035|protein_coding 374 CAAG CT frameshift&splice_region|GTF2I|ENST00000573035|protein_coding bcftools-1.21/test/csq/ENST00000573035-bt2212/complex-event.vcf000066400000000000000000000006101467060157400230440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 7 374 . CAAG CT . . EXP=frameshift&splice_region|GTF2I|ENST00000573035|protein_coding bcftools-1.21/test/csq/ENST00000573314/000077500000000000000000000000001467060157400166475ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000573314/ENST00000573314.fa000066400000000000000000001005711467060157400210030ustar00rootroot00000000000000>15 15:65871071-65903647 AAGACAGACCAAAAGCAAACGACCTTTAGTTTCATAGTGAAACCATTTTCTAGAAAATCA AATATTTTATTTTCATTAAAAAAAAACCTTGAATAATAGGAATCATTTTACACATTAATG GTTGCTCTTTAAAAGTTAGAATCTCAAGAGATACCAAAAGCACTTAAGAGTTACCACCAC ATTTTGCCCAAGTTCTAAGGAAAGTTCTGAAACTTAGTGGTGGTGTGTTTGTACTCAGCA AGCTCCAGACAGTCTGAGTTGCTCATTCCATGAACAGAAGCTTGAAAATGCCCTTACAGT TGAGATATAAACGAGGGAAGAGGTGAAGCTTTCAGGAAGCCAGAGAGCCCCTGCCGGTCA GGTTTCCTGAGGAAGGCAGGGGTGCTCTATGCTCATCAGTCATTCAAGCTTCTCAGGAAA TGTGCCCATCATGGGAACAGCAGCTATCTTCCAAGCTTAAAAATTATGAATCCCAGGAAG TTAAAGCCCAACCAGCCAACCACCTTCACATCCTTCTCATACTAGTAGAGTCATTCAAAA CAGCAAGTGGTGCTTCTGAGGCAGCCTCAGGAAGGTCTTTGGGTGGCTATTCTAGAGGTG AACATACTGGAAAGGTTTTTACCTAAAGCATTTTCAGTTGAAATGAAAAAAGAAGGAAAG CTCCAAAAGTCAGTTTCAAATTCTTTCAGTGCTGCTCCCAGAGAAGTCCGTGTGCAAAGG TGTGATGTTCTGGTCATAAGCGGCATACTCAGAGGTGCCGGTACTGGCCAGCTTGAGCTG CTGGGCAGCATGGGTCAGCTGGAATGCAGCATCAGGGTGGGCTGTCTCAGGCAGCAGTGT GCATTCCCTTTCCAGCATGTCAGCCACCCCTTTCAGCAGGTCCAGGAAACCAAAGGCTAG AGCGGCCTTTCGCAAACGGTTCAGCTCCTGAAACAAGACAGAAAATCACCAATGCTCCTG AAATGTGTTCCTAACACATACTTTCTAAGTGCTCAGCTTAGCATAAGTTCTCCTTGACTG AACTTTAGGGAGCAATTTTATATGAGAACAAATGTTTATTTAGGGATGCCAGTAACAAGA ATGTGATGGTTTTACTGGGAAGTGGTTCCTCTGCAGGTGACCAGAAGCAGGCTAAGGAAG ACAGCTGAATGAAACAACGTCATCATCACAGTTAATGAGCATTTATGCCACATGTGGTAG TCAGCACTTTGCATCCATCATTTCGTTACTCCTAACTTTAAGGAGGAGTACTTTTCCCCT GTTATTTAGGTATGGAAAAGACTTGCCCTCAATCTGAAAACGCTCTTAACCCTCTGATGC CACTGTGGTGGGGCCTCAGGCTAAGACAATAAACAGGCTCAAGAGGAGGCCCTGGAGGAG TCAGAGTGGAAAGACCAACAAAAAGAAAGGCTGGTTACTGATAGAAGCAGAGAAATATGA AGTGCCCCAACAACCCCTTAGTGGAGTGGTCTGGGCAAGTTATATAGCCTCTCTGGGTCT CAAAGGCCTCATTTATAAAATGAGGAGAATAACCCCTTCCTTACCCACTGCAGAGGCTGA AGCACTTTCCCTAGGCCCTTTTGAGCTCTAATATGTAGCATTATATAAAACCAGAAAAGA GAAATGGGCTCTCTGACCATCTTTCTACTATCATCTGTTAAAAAAGTGGAAAGTTAAGAA GAAGGCCAAACAAGTGTGTCATCATGAGTAAATAGCTGATGACTGTAGGAAGCTCTGCAG GGAGGATGGACTGTGTGGATTATGGGCTTCAGTTTAGGGAGGGGCCTGGCTGGCTAAGAA GCTCTCCAGTTGAACTCTTGATTAAAGCTGTTTTATTTCACCAGCTTACTACATAATTAA GTTTGAAGACAACAGTGACATAAAGGTAATGAGATAACACCCAGACAAAGTAGCATGTAT CTTCTCTGGTTAAGATGCTAGCCTAAGGCTGGCTGTGTGTGCCACATTTTAGAATTAGAA AGCTAAGACACAAATGACATACTTTATGCTGCACTTAATTTAATTCCAGCCAAACACCAG AACAATAGGGGAGAATCAAGGAGCAAACCTAAATGTTCCCCACTCTACCCCACCCCCTGT AACTTAACAGTCTCTTCACCAATCGTTCTGGATTAGCTGCATATGATTCTGCAGGGCTAT CTCCTCTGCAATTCATAAATGTGTAATGTTAGATATCATTCCTAGAAGCAGAGTCTCTGG TGCAATAAAAATGTTCTGGGGTGGCCAGGTGGGGTGGCTCACGCTTGTAATCCCAGCACT TTGGGTGGATCACCTGAGGTCAGGAGTTCGGGACCAGCCTGGCCAACACAGCGAAACCCC ATCTCTACTGAAAATACAAAAATTAGGCCGGGAACGGTGGCTCACGCCTGTAATCCCAGC ACTTTGGGAGGCCGAGGCGAGCGGATTACCTGTGGTCAGGAGTTCAAGACCAGCCTGGCC AACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCACAC ACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGTTTGAGCCCGCGAGGCG GAGGTTGCAGTGAGCTGAGATCGTGCTACTGCACTCCAGCCTGGCCGACAGAGTGAGACT CTGTCTCAAAAACAAAAAAACAAAAATTAGCTGGGCGTGGTGGCACGTGCCTGTAGTACT AGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGTGAGGCAGAGGTTGCAGTG ACCCAAGATTGCACCACGACACTCCAGCCTGGGCAACAGAGTGTGACTCCATCTCAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAGAATGTTCTGGGCAATTCCCCATCCAGGAAGCCAC ATACATTGGTTGCCTGGGGTTGGCCTGGATACCCATATAGGAGTGATGAGGAGAGTTCAG GGCTATGACCCACAGGTCCTCTAAGCTGCTTCCATCAGTCATTCATTCACAGCAGCCCCA ACACAGAAAAACCTTCTGCCTGTACAGAATTAGGCCATTTAAATTCTTCCAATTCTTGGA TTTTAGGGAAGGAACAGACCTATCACTTTTACTGAGTTTATTTGAAAAAACTGAGGCACA AGTCATACATCTCTAACCCCTGCCCATATTCACACTGCCATCTCACAGTTTTACTGTCGT GAACCATATATTTTGGGCACATCCTCTTCTGTCTGTCTCACCTTATAGAATGTCTGTGTT TTTTCAGGTAGTTTCCTTGCATTTCTTAAAATCTTCTGTACATCTGTCTATTAAGGGTAA AAAAAAAAATCCAACATTAGAATTCTGTGGTAAAAAAGGGAAATAATATAAAAGAATGGA TCTAAATGTTTAAAGAGATGAAAATGAGAACACAGCTACAATGTCAAGATGAGGATCCCT TCTGAGTTAATGTCAGTTCAACATTAGTAAAGCACTCCCTCCTTCAAAAGGCTTGACAGT AAAATAAATCCCCTGACAGAAACGAACTTGCCTCATAAAAATGTACCCAGTAAACCCATA CATCTATTGCCAGGGACTTTTTTGCAAAGACGATTCAATGGGGAAAAAATAGTCTCTTCA ACATTTGGTGCTGAGACAACTGGATATCCACAAGCAAAAGAATAAAGTTGGACCCTTACA TCATACCATATACAAAAAACTAACTCAAAATGGATCAGAGACCTACATGTAAAAGCTAAA ACTATAAAACTCTTAGAAAAAAACGGGCCAGGTGCAGTGGTGTGCCCCTGTAATCCTAGC TACTCAGGAGGATTGCTTGAGGCCAGAAGTTTGAGACCAGCCTGGGCAACGTAGTGAGAT GTGTTTCTCAAGAGAAAAAGAGAAGAAGAAAAAGAAAACACAGCGGGTAAATCTTTATGA CTTTGGATTTGGCAATGATCTCTTAGTTAAGACAGCACAAAGCACAAACAACAAAAGCAA GAGACAAAATTTGACTTCTTCAAAACCAAAAACTTTGTGTATCAAAGGACACTATAAAGA GAGTGAAAAGATAACTCACAAAATGGGAGAAGATATTTGCAAATCATGTATCTGCTAAGG ATCATAATATCCAGAATATATAAAAAACCCAACAACAAAAAGACAAACCCAATTAAAAAA TGGACAAAGAACTTGAGTATATACTTCTCCAAATAATATACACAAATGGCCAATAAGCAC AGGAAAAGATGCACATTATTGGTCATCAAGGAAATGCAAAAACAAAGACATACCACTTCA CACCTACTATGATAGCTATATGATAATAATAATAAAAGGAAAACAATGAGTATTGGTAGG AACGTGGAGAAACTAGAACACTTATACACTGCTAGCAGAAATGTAAAATGGTGTGGCTGC TGTGAGAGAGTGTGGCAATTCCTCAGTAAGTTAAAGAGAATTGCTGTCTGACCCAGCAAT CCCATTCCCATTAAAATATATACCCAAGAGTATTGAAAACAAATGTTCAGACCAAAACTT ATACATGAATGTTTGTAACAGCATTATCCACAATAGCCAAAAGGTAACCCTAATGTCCGT CAACTGAGGGATAATCAAAATGTGACATATACATATAGACATATGGAATATTAGCCATAA AAAGGAATGAAGTACTGATACATACTACAACATGAATAAACCTTGAAAACATCATGCTAA GTACAAGAAGTCAAACACAAAAGGCCACAAATTGTATGATTCTGTTTACATGAAATATCT AGAATAGGTAAGTCCATAGAGACAGAAAGAAAATCAATGGTTGCCAGGGCCCGGAAGAAG GAATGTGGAGTGACTTTCCTAATGGGCACAGGGTTTCCTTTTGGAGTGATTAAAATGTTC TGGAACTAGAGAGTGGTGATGGTACATTGTGAATGTACTAAATGGGACTGAATTGTGTAC TTTAAAATGGTTGAAGGTACATTTTATGTATATTTTACCAGAATAAGAAAAATAAACCCA AGATAGTAGTGAAGATTCAAACAAAAAAAATTAAAAAAAATAATTTAAGAAAAGCTCAGC TATAACTGGTGGTGAAAGTGGTTCTAATATCCCTCTGACAAGGAAGCACTGGGGTCAGGG ATATCAGGAAAATAGAAGACCCTGATTTTCCAACAAAGAGGCCCCTGACACTTTAGCCTT GGCAGGATGTGGTTCAGTCTCCATGGAAACGGGGCTCAGAGACTGTGCAGTCAACAGAAA CTACTTTTGTTGTCCAAGTGGCCTGTCTCTTCTCATTTGGTTTAGGTTGAACTTACTGGA AGAACAAATGTAAATAAAGGTGCTCAAAGGAGAAAAAAGTTTCAATAAGTGATTTTTAAA AACAGGTATAAATGACTTTTTGCTGATGAAAGGAGAAATGTTCCTGAATACCATGCCTGA AAGCATCATTCCTTGATAATCATATTATCATATGTTCCTGAATACCATGCCTGAAAGCAT CATTCCTTGATAATCATATTATCATAACTTCCTATGGAAGTGTTTTTGTGAAATGTAATG CTATGGCTTGAGTTCTACTGAAGGGATGGAAGAAATATAGTTATGAAGACTTTTACATCT TTTCCAAAACTGTTGTTAAAGCCAATACCCATTATGTTAGTCAATGCCTCACCATATAAA AAATTTCACACTAAAATTCAATGCCAGGAAAATATGTCTCTCTAGACAAACTGACAAATT TCCTTTCTTTAGACAAGAACAACTGACCTTGGTAACAGGAAGCTCAGAGCCAAAACACTC ACATAAAGTTATTATTTTGCCTTGGGTTCCTGGCACAATTGTCTTCCTTCTTCCTCCTTC CTCTAGGATTCTTATTGCTCTAAATTTTGTAAAAAATGATTTTGCTATATACATGTTTTA CTGTAGGGCATCTCAAATCCCTTTTGGAAATAATGACAAACATTAGAAGTAAATGAATTA CTAAGTATCAAAGGAAAAGAAAATCAAATAAAATGCCTGCCTGCCTACCCAAATGTCTCC TGTCCCCAGTGGAAAGCAACATAAATGGTAATGTTACCTGCAGGCCGCTGGGTTTGATCC AGACAGTCACATTCTGGGCATAACTGCGTTTGTTTTTGGGCTGCAGGGGGAATGGACTCT TATTGTCATCCTCGCCATAAGGGTTTTCTTTAGCATCTTAAAAGAAAAGACATTCTTGAA ATGACATCTGGTAAAACACAATCAGTTACATTTCCATTTAGACTAGAAGCTCTTTGAATC ACTCAATCTTTGATATCCTATCACTTTGTTAATTAAGAAAATCCATTAACTTCAGTCAGG TTGGAGAACCTGTTCTCAATAGAAAGCCACTGATGTAGGAGGCCCATTTAAGTGAAAAAC AGCTTAATGTTTTTAAAGAAACAAGCTTCACTTATCTGATTTATAAATTAAGGTCAAAGG ATAAAACAAATACATATTTAAAAAATATATATATATATACATACACATAGACACACATAT ATATACTGCAATTCTATATAGTCTAACCCAGTGCTCTCCAACTGAACTTTCTGTATGATG GAAATGTTCTATATCTGTGCTGTCTAATGTGGTAGCTACTAACTACTAAGCACTTGCCCT GTGGCTAGTGTGACTGAGAAACTGAATTTCAAATTGTACTTAATTTTAATTAAATTTAAT GTGGCTAGTAGCTACTGGATTAGACAGCATAGGTCTAGGCATTAAAATAATTAAAAAGGA AAACTATATATATAGCCAAATTAAGGCAAAGGGCAAGACAAGAAATACTTTTATTGGTGA AGCATACCCCAATATGGCTTATTAGTTTATTGCTTCCAAAAATGTAAAGCCACATTGGTT TTATAGCTACATGAACAAACAGGGTTTGTCTCTGTACCTGCTTCCTGAGTCTATGAAACT GCCACAAACTTATAAAGCACACATACTTCTAATGGTGTATTTGATCTTTATTATTATTAC CACCTTCTCGTGTAGACAGAGCAGGAGTCATTTTCCTACAAGTTCAGAGAACTTAAATCT CTTGCCCAAAAGTTTGTGTTGAAAAATGTAATTAGACCAGTCTGTCTAATTGAGCCAGAC ATTCTCTATCCCTGATTTGGTCATTAATTGAAACACCTTGATATTGGACCAACACTTCCT TTGTCAACCCTCTTCAGCCCTGACTCCTCCATAAAATACTGGCCCAACTCTCCAGACGTA TTTCCATTAATATTTGTCAATATATAAACCTTCTGAGTCAGGCTAAGGTCCTGCAAGTCC TTTCCCACACAACAGTTCATTTCCAACTTTCCTGCTATTTCTATTACTCCTCACTGCCTA GAATGCTCTCCCTTCTTATTCACTCATTTACTCATTCACTTATTCATTCATTATCTATAG TAAGACCCCACTACGTAGCAAGCACTGTGCCAGGAATTGTGCCTAGAGAAGATACTTTTC AGCCTCAAGGAACTTACAGAATAAAGAATATTTATTAAGTTCCAACTATGTGCAAGATAC TTTACATATTCAACTTCTCTCTTTATAGCAACTCTAGAGCGAAGATGTTATTAGTCCCAT TAAAGATGAGGAAACTAAGGCACAGAGAGGTTGGACTTATACAAGGTTTCACAGTGACTC AGTTGGGCCTGCTTCAAAAGCCAACACTTTTTCCACCATTCAACACTGCTGTTCCTTACT TATCCAAACTTACCTACCTATATTCCAAGTCCAGATCCTATCTTACCCCTTCCATGAAAT TGTTTCAAGTTTTTCTGGCAGATAGTGGTTTTTGTAGACCCTTTTATCCCCTAGCACTTA GTATCAGTACCAAACATTTCAACATCTAATCAGAGCCTATTTTGTACTGTCATTAGTTGT CTGGAGCCTATATGTGGTAACTAACTGGCTTAGGAGACAGGAAATATTACATTTATGAAA GAAGAAATTTTAAAAAGATAGTATAAACAAAAAATAAAAGTTATAAGATAAATTTGAAGA TACAGAAGACAGAACAAAAATTTTAAAAATGGGAAAATGGGCAGAAAGAGATAGAAAATT ACAAACACAAATCACAAATATATGTTCCAGAAAAGGAGAACAGAGAATACAGAAAGAGGA AATCAAAGAAATAATTGATCTTCCCAGTACTGAAGATCATGAATTGCCAGATGGAAAGGG TCCACTGAGTGCCTAGCAAAATCAATGAAGAGACCAACATTCTGAAATTCAGAATACCAG GGATACAAAGAAGATCACCAAGGAATATGGAGAAAATACAGTTCAGGGTCAAAGGTCTTT GAGTCACCATGGCACTAACTTTCCGTAGCAACACTGGACTCCAGAAGAGACAACAGAGTA ATGCTTCAAAACTCTGAGGGAAAATGACTTCCAACTTAGAACTCAATTCCCAACCAAACT ATCATTAAATATAAAGAATGAAATAAACATATATATATTTTCAAAATATACAAGATTTCA AAATATTTACTTCCCATGTACCCTTTTTTTCAGGAGGAGTTATGAACAGGAGATCCATAG GAGAGATGTAAAGGGGAGACTCAGGACAACACCTATGCAACAGGTCTGGGGAATAACCAT ACCATTTATGAAGCAGGAGGATGGGAGATGACGCTAAGAAAAAAAAAGGAAACTGAGAAA ATACCTGAAGAATGTATTTTACTTAGGGAGGAATTAGTTATATAGAAAACAAGCAAAGAA AAAAAATAACTGGGACTGAGCTAGGGGACAAAAAGTTGCAAAACAAAGGAAATACAAATT GGTATAGCTTAGTTGTAAATAACATTTACATCATGTAACAAGGACTGAATACTGATTTAA CCAAAAAGAACATTATAACTATATTGGGAGGATAGTAGGAGGGGAAATGTGCGTCTTGTG TAGGTGGGTGGGAGATGGTGGTGTTAATAGAGCTAAATATTCATCCTTTAAAAAGTCAAA AAATGGCATCTAAAATGGGGGAAAAGGGCTGAGTGTGGTGGCTCACGCCTGTAATCCCAA CAATTTGGGAGGCTAAGGTGGAGGATTGCTTTAGCCCAGGAGTTTGAGACCAGCCTTGGC AACATAGTGAGATCTTGTCTCTATAAAAAAATCAAAAAAATTAGCCAGGCATGGTGGCAT GCACCCGTGGTCCCAGCCACATGAGAGGTTGAGGTGGGAGGATCACCCGAGAGGTCAAGG CTGCAGTGAGCCAAGACTGTGCCACTGCACTTCAGCCTGGGTGACAGAGTGAGACCCTGT CTCAAAAAATAAATAAAAAATAATAAGACGGGAGGCCGGGCACAGTGGCTCGTGCCTGTA ATTCCAGCACTTTGGGAGGTCAAGGCGGGAGGATCACTTGAGGTCAGGAGTTTTGAGACC AGCCTGGCCAACATGGTGAAACCCCGTACCTACTAAAAATACAAAAATCAGCCAAGCGTG GTGGTGGACACCTGCAGTTCCAGCTACTGGGGAGGCTGAGGCACGAGAATTGCTTGAATA CAGGAGGCAGAGGTTGTAGTGAGCTGAGATCACGCCACTACAGTCCAGCCTGGGCAACAG AGCAAGACTCCATCTCAAAATAAATAAATAAAATAATAATAATAATAATAAAATGGGGGA ACCCCTGACAGAAATAGGGACATACCTATATTATTTAGAAATGTAAATAAGGCTGGGCAG AGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGG TCAGGAGTTTGAGACCAGCCTGACCAACAACATGATGAAACCCTATCTCTACTAAAAATA CAACAATTAGCCGGGCATGGTGGCTTGTGCCTGTAGTCACAGCTATTAGGGAGGCAGAGG CAGAAGAATTGCTTGAACCTGGGAGGTGAAGGTTGCAGTGAACCAAGACTGCTCCACTGC ACTCCAGCCTGGGCGATGGAGTGAGACTCTGTCTCAATTAAAAAAAAAAAAAGAAATATA AATAAATACCAAAAGAAACAAATAAGTTTTAAAAAGTAGTTGTCTCTAGGAACAGAATTG GGAGTAGGAGGGATTGGTACAAACAATAGTGCTATTTTGCATGTTTTGCTCAACAACCCT CTGAGGTAAGTTTTATTATTAATTGTTATTTGTTATCATAATTCCAATTCCAAGACTGCT GTGAGAGTTAAATGAGATGGTATGCTCATTATGTCCAGCACAGTGCCTGGCACAAAGTTA AGTTCATTATAATATTAGCTATTATTATCCACACTGAAAAGCAGAACAGATCCAGGAGGA AAAAACAACATGAACACAGGGCAGAGTGAACAGCAGTTCAACTGGAATGAAGAACAATTG TAACAAGCCAAGTGTTGCTATGTTGGAAGCCAGATCAGAAAGGAGTCTGAATGCTACTAC TATCTTAGATTATAGATAGGCATCTTTGGTGAAAACCATCACAATAGTCTAGTCAGAGGT TGGCAAACTTTTTCTGTGAGGGCCAGACAGGTTGGAGTGCAGCGATGCAATCAGGGCTCA CTGCAGCCTCTGCTTCCTGGGCTCAAGCGATCCTTCCACCTCCGCCCCCTGAGTAACTGG GACCACAGGTGCACACCACCATGCCCAGCAAATTTTTGTATTTTTGGTAGAGATAGGGTT TCGCTATGTTGGCCAGGCTGGTCTCAAACTCCTGGACTCAAGTGATCCACCTGCCCTGGC CTCCCAAAGTACTGGGATTACAGGCATGAGCCACCACACCTGGCTGAATATTTATCATTT CTTTGTGTTGTGAATATTCAAAATCCTCTCTTCTAGCTGTTTGAAAATATACACTAAATT ATTGTGAGCAATATTCAGGCTACCATGCTACAGAGCACTGAACTTTTTCCTCCCTAACAG CTGTAACTTTGTATCTGTTACCTCTGCCTATTCTCCTCTCCTCACTACCCTTCCCAACCT CTAATGACCATGATTCTAGATTCTACTCTGTACTTCTATGAGCTCATTTTTTTTCAGCTT CCATATATGGGTGAGAACATGTGGTATTTATTCCAAGTTTATTTTTGTACACAAAAACTC AAAATTTGTGAACCACTGCCCTGAGCAATCTCCCTCATTCTCACCATTTTAACTATTTAT GATAGGCTTACAACCTAAAATTTTATCTCCAACTCTGCCCTCTCTCCTAAACTTCAGACT TCTACAGAATTGTCTCTAGGTACCTCCACCTGTATCTCACAGGCACGAACTCAACATAAA CAAAATATGTTCTTCCCAAATTTACTCTTCTCTCTGTATTATCTATTTCAACTAATAGTA CTATCTTTCACCCTGCAGCCCAGGTCAGAAACCTGGGATCAATTTTAACACTTCTCTCTC CATAATTTTCATATCCAAACATTATTGATCCTACCTCCTAAATATCTTTTACCCCCAGCT ATTGCCACGGTCTGGCTCTCATCTTCACATTTCCAGGATTAACACAGTAACTTTCAGCCA CAGGTCCTTGCCTTTTCAGATCCACACTCCACAGAGATATCTTTCTAAATACAAATTTCT TATCTCTCACTTGGATTATGGCCATACTGTACAACTGCAGGGGGCACCAGCCCCTAAAAT ATAGTTTCCTAACTGGTATCCCCCTGTTCTCACTGTAGCCAGAAGGATCTGATCACATTA CTCCTCTTCAGTGGTTTCCCAGTATCTGCAAGATAAATTCCTGGTTCTTCACATTTCAGA CAAGGCCTGCTCCACTCTAGCTACTACCAATCTCCAATCTACCATCTGCCCCTCCCACAC CCACTCTCACATTTTGTGCCACACTTCCTTTTCTTTCTGTAGGTGTTCTGTTTGCCCAGG ATGCCCTTTCTTCCCTTCATTAGCTCAGCAAGTTCCTCCTTTTCTTCAAAACTCAACTAG GGTATTTCTCCTCTGTGAAGATTCTCCTGAGTCCTCTAGGCAGAGCTCATCATCATCTCC TCCAGGCTAACTCTGATTTGTGCCAGTCTGTGATCATTCCACTTTCCACTAGACTTTGAA CAACTCCAGCTAACTCTTTATCCCTTAGGCCTGGCACAGAATAGGTTGCTTGGTAGATGT TCCTGAAATTGAAATGGGCCCAAATGAGTCAAAGATGACTACAGTTGGAACCTGAGTAGC TAGTGGCACAAATGACTTAATCAAAAGGAGGAGGAAAATCAGAAGGAGGAATAGTTTGAG GAGAAAGGGGTGCGGGACAATAGGTCTGTAACAAACAGCTGAGCTTGAGACTGTGACAGA ATATCCAGGTGTAGAGATCCAACTAGGAACTGGAAATATGATATGCAAATTCCAGGGAGA GATCAGGTAAGACTAGAGTTATAGATTTGGGAAATGTGAAGTTATTACAGCTGATAAAAT AACCAAGGGAGAAGAATAACCAAAGAGAAGAAGGCAAAGAACATGTTGGAAACCATGAGG CAAGGAGAAGAAAAGACAAAACGAAGAGAGAAAGAAAAGTCCGCCAAAGAAAAAGTCAAA TCGGTACCAGAAGCAATGTCAGGAAAGCTACAGAAAAAAAGTTTCAAGAAGGAGGAAAGA TTACATTATCTAGGAATGACAGGAAATTACTTGAACTATAGTACACCAAGAAAAAAAATT ATGGAGATTAGTTTTTCACTCTAAGCCGCTGAAGAATTTGCATTTACTTAAAGCAATCTA AATGTTGATTTCTCCTGAGCTGTAAAATTTAGGAGTTCAAACATCAAACTCTCTTCAAGT TTTCACCGTACACATCCAGCATCATCCGAGACCATGGCATACCAGTAAGGGAGATCAATC AGTTCTCTGACTGCACAGTCAGAGACATTGAGAACAGCAGAATGAAAACAAAGTCAGGAT AAGTAAAATCTGATCTGGATTATACCTGAAATAGGACCCAACTGTGCCATTTTCCCTAGC CATGGGAGAGGTTCTGGGCCAGGCTCAAAGAGAGACATCATGAGGTTTGATTTCTTCTTG CTGTCAGCTTGGGAGTAGAGCATTCCATGCCATTCAGGACTAGATGGAGAGAAGACGGAA GATCAGAAGAACATCAAGCCTGAGACTGTCAAGTTAAATAAGTCTAGCCTGTATTTTTCT CTTGAGAGACACAGGCTTCAGCTTTGAAATCAGGCACACTACTTTTACCAAAGCCAAACC CTAAACCTGAAAATGCATACTGCTGTCCCCTAATATTTCCATTCTTCTGAGACATTTATT ATTATTCAGGTAAAATTATGTGGATATGGAAATCAAAAGCAATCTTGAAAGAGAAAAAAC AAATCACAAAGGGCAGCAAGTAGCTGGAGAGGTGATGAGGAGGGGTAAAGGCTGTGACCT ATAGGTCCTGTCACCTGCCTCACTGAGTCACTCACAGCAGCACCAAGAGAAGCCCTTCTA CCACAGGGCTCAAGGCCATCATCCTGTTATGTAAAAGAGACTCTGTCCCCAGTTTCTCAA AGGGTCCCAGATGATTCTCATATTCAGACCAGTACAAGTAGCTTGGGTGCCAAGAAATAT AGCAGACTAATATCTAGTAAGATCTGCATTCCTCTTTTTGGACCAGCTAATTTTAACTGT AGCAGAAATGGAGCCATGCTTCCTTTAATTAATCCTAACTCTTGATCTATACCAGCCAAC CCCAGGTAGTGGCCAGAAAATGATCAGTGACCTCCTTTTTTCTAAAAATATGTATTATAG AAAGGGAAATAGATGGTTTTGCAGATTTTGAGACTTCAGAAAATGTAAAAGCTAACGGGG TTTCCTCACAGGGAAGGAACACAGCAGAATGATTATGAGTAGGCTCTGGAGTCAGAATGC ATGGGTAAGAATCATGGTTCTTTCATTACTAGCTGTGTGACCTTGGGCAAGTTCCACAAC CTCTCTTAAGCCTGTCTCCTCATCTATAGATAGGGATAATGCTGATACCTCCCATATAGT GTTGTTATGAGGGATTAAATGTGCTAACATATGTAAAATACCTAGAGGAGTGCCTGGCAC ATAATAAAATGCTCAATGTTATTAGCATCTTTTTTTTTGTTTCGTTCTATCCCCTCATTT TATAGATGAGAAGTCTGTGAATCCTGCCTAAGATCCTAAAGCAAGTTAGTAGCATTGCTA TAACCAGAACCCAGGTATTCTAGATAGGATTAGAAAGAGGAAAATTGAGAAAGGATATAA AATAAAGGCAACGTAATTAAAAGGCTCACTCCACACTTATTCTAGGGGATGATTAAAAGA GTAGTTTAGAAGGTAATAGCAGCTAGGTACTGTGGCTCAATGCCCGTAATCCCAGCATTT TGGGAGGCCAAGGTGGGAGGATCCTTGAGCCCAGGAGTTCAAGACCAGTGTGGGCAACAC AGTGAGACCCCACTTCTATAAATTAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGGT GCACACCTGGGTCATGGCTACTTGGAAGGCTGAGATGGGAGGATTGCTTGAGCCTGGGAG GCTGAAGCTGCAGTGAGCCGTGATCATGCCACTGTACCCCTGGGGGACAGAGCAAGACCT CGTCTCAAAAAAAACAAAAAAAAAGGACTGTAGTAGCAGGTGGGAAAAGTGTGTGGCAGG AAAAGGAAAAAGGTGACAAGGACCTTTCTATTTCCTTCAGAAAAGTCTGCAAAATACTTC ACTTTGTAAAATGATTTTCCCTTTCATTCAACCAAATGTAAACAAAGTTTCCTACCCTAA TTGAACAATCGCTACCATTCCTTCCACTTTTAGGCTACCATGGAGCAGGACACAAAAGTT GGGTATTTTGCCTGCAATCTGATTGGCTGAATTTTCATCTTCATTGTCATCAGTGATGCC AGTACCCACCTCATCACCTTCTGTGAAAAAAAGAGAAAACAGGTCAGACTGAAATTACCT ACAAAAACCCCAAACCCCAATTTATACTCTTGGATGTTTCTAGCCTTTAAGGGATAGTGT AGAGTTCTAAGGGAATATTATAACAAGCAGGAAAAACTCATTCCAGTTTTCCAATATCTA CATAAAAGTCAGTTTCCACACATTATATGAATTCCATTTATATAAAACATCCAGAATAGG CAAATCTATATATACAGAAAGGATATTAGTGGTTATTTGGGGTAGGGGAAATGGGGGGAG GGGTCTGGGAGTTGATAGTTAAAGGGTACAGGGTTTCTTTTTGGGGTTATAAAAAAGTTC TCAAATTGATTGTGGTGATGGTTGCACAACTCTGCAAATATACTAAAAACCACTTTAAAT GGGTGAAGTATATGGTATGTGAATTATATCTCAGTAAAGCTTACACACAAAAATCCATTC TCCACAGTTCCACTAGGATGTTTAGTTAGATGCTATCTGGAAGCTTCAGGCACCCATTTA AACAGAATTAGATACAGAGATGTCAAGTGCATTCATAACCAACAGGCTTAGGGCAGCACA TGCATGTGAGTCCCCAAAGGTAAACAATGATTATAAGCTTTTTGACTGGATTCTCCAGTT TCTCTCACACTCTGCTGACAGATGAATCTTCCTACAATTAACTTCCCTCTAAAAATATCT GTCTGCTCTGCTTTGTTCAAAGACTTTCTAATTCAACAGGAAGAATTAGCCCAGTTTAGC TAGAAAATTCAACAGCCCTTACAAAATGGCCCTACTCTGCTTTCCCATATTTTTCTTTTT CTTTCTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCTCAGGCTGGAGTGCAGTGG CGCGATCTCGGCTCACTGCAAACTCCGCCTCCCAGGTTCACCCCATTCTCCTGCCTCAGC CTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACTACGCCCAGGTTTTTTTTTTTTTTTT TTTGTATTTTTAGTGGAGATGGGGTTTTACCATGTTAGTCAGGATGGTCTCAATCTCCTG ACCTTGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTACCG CGCCCGGCCACCTTCCCGTATTTTTCTTTTCACTATTCCCCTATATAAATGGTTTATTTT GCTTAATTTCTTTCTTGGTAAGTATACTGGCATGCAGAATTCCCCAGGGCCTTAGAACTA AGGGAAATCTGGCTGTTCTCTGAGAATAATAATTACCAACACAGTGATTATAAAGCTGTC TGTGGGTATATATTCAAGATTCTGTCTGTGAACATGTGATTGGTTATAGAATATCCAATA CTCCAACTGAGATAACCTGGGCATAAATGGGATGTGGTCATTACTCAGTATGTGAAAACC TGACTGACTACATACAGTTCTTAGAGAAAGCTGATAAATATAAAGTGGATGGTCAGCTTA AAACAGAGGAAAAGATAATTTTAAGGGTAGAACTAGGATTTGAACCTGTAGCCAGTCAGG GACAAAAGCTCCTGCTCTATACCCACCACAGCACAGTGCCACCCCTGAAAAAGATAATTT TAAAGAGTTAGAGTCTAGCATTCTCCAGAGAGATGCTGAATTTGAGGAGATGACTTTATA GTTCCTAGAGATATATGCTGCAGTAAGGAGGACCCACAAGGGCCTGGATTCACCCATTCA TTCAACAATATTTACTGAGTTATCTACTATGTGCTGGGCACCAGTAGAACAAAGAACAGA TGTGATTCTTCCGTGTATAAAGCTGTATTTGACTTGCACATTTATCAAGTAACCATCTGA TAACTACTTAAGCTTTCTCAGCATGTTAGTACTAGGAAAGGCAGAGCCCTGGATGAGGGA CTAAGCATTCTCATCTCTAAAGAGGACCTCCACTGTCAATTCACAAACCAACACACAGTA AATATGTGTCAAAATGTTTCTACCATGTAAAGCAGAATTACTTTTTTGATATATTAGGCA ATATTCCATTTTCTAAAATCCAATTCTGTAACTATTCCTTTCCCCTAAATTCTGCAAAAT GGGCTATCCTACTATCTAAGATTTAAGAACAACTTTAGTTAATAAGACGCTTCAGACGTA TCAGTGGAATAGGAACTCACCTTTGTTAAGTGCTATAGGTAAGACCAGATGTCTGGACAG AACTGGGGGACTTGAAATATCAGCTATATCAATAAATCCCACTATTTCCAAATCTGAAAT GAAGGAATCAACACAGAATTAATTCATTCTATGGAAAAGTACATTATTTTCCATGTATTA CATTTCACAAATGCACTGTTTAGGTTGGGGTTTCAAATATGATGACTGGGAAAGTTATTA GATTTGTATATGGAGTCGTCTAATAATTTGCATTTTAAGCTGCTCAGGAAATAATGATAA CTGTCATTGATTTAATGAGTCTAAGTTATATGACAAAATCAGCTAAATTTTATTTTTATA AGGTTAGGACCCCAGCCAAGGCAAAAACTGAAAGGTCTAATCCCTCTGTGTAGTCAGGGA TGTTCAGGTCACCAGGGGGCATCATAGTCAAACACTTCCGCAGCAACTACACTCAGCCTT TGAAGAATAAAGCTATTGTATTAAAAACATCTCTCTGAGAAAGAACTGTATTCTCTACAA AACTAGGGTAAGCAGTCTAAATATGACAATGACTTCTCTGCTTTATAGACGCTGTAGTAA AGACCAAAAGTATTTGTTGAAAACCTAAAATAAATAAAAATGAATGTTGTAACCAAAAGA ACTTAAACATTTCGATTATATAATATAAAAACTTAAAAACAATAAAAATTATAAAGAAGA AAAAGTCACTCATTATTCATAATCAAAGGAAATCTCTATTAATATTTTATTGATGTGCTT TTCAGTCTTTCTTCTAGATTAATACCCATATTTTCAAAAGAATTTTTAAAAATCAGAATC ATGGTGAACACCTTATATTTCTTTTTTCTTTTTTTGAGATGGAGTTTCGCTCTTGTTGCC CAGGCTGGAGTGCAATGGCGCAATCTCAGCTAACTGCAACCTCCTCCTCCTGAGTTCAAG TGATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGATTATAGACATGTGCCACCACGCCTG GCTAATTTTGTATTTTTAGTAGAAACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCCCG ACCTCAGGTGATCCGCCCGCCTTGGCCTCCCAAACTGCTGGGACTACAGGTGTGAGCCAC CGTGCCCGACCCTATTTCTAAAATATTAGGAAGTGTGCTTCTCTGGAGATTTGCTGTCCA TACCTCCCTTAGCTGAGTAATAAATGCATTAGTATAAGCAGCTAGATATTTTTCATTTGA GTAGAAAAAGGTCTACTTTATTTTAAAGCAGTTTAGCTGCAAGAAAGATCTTCCACTAAG AGTTTATATGGGAAAGAAAAGACCTATTCAAATTTACTCATCGAAAAAGGATGGGAAGGA AGTGGAATCTAACTGTTATGAAGGCAACAAGACTTTTGGTACAACTTAATGTACTACTGT CTAGTCACAGTAGAAGAGATGGATGCCTTGCTTCCAGAAGCTAAAGGCACAAAAAGTAAA AAGACTGTTCACAGCCCCTCACTCCAACACTCCTTAAAAATCTGTATACCACAAACAATG AGCATTCACTGAACATTTAATTCTAATCATTTATTGACTGAACAATTACCTATTGGGCAC CTACTAAGTGTCAGGCACTATGCTGGACATCAAGGCTGTAATGGTGACTGAAACACTGAT AATATCCAGCCCTAAAAGATTTAACATGCACCTAAGATTCAAGGAGTCCACCCACCAATA GGAAGCAAGTCTCCTCTCCACTGCTCCTTGCTATTTTTGACTCTTCACTTTGCCAGTCTC AGTTAAGCATAGTATTGGCAACACGAACCAGGTAAAAGCTGTGGTACATCACTTTCTTTC AGTCATAATATAAGCAGCAGTGCTAGAAGAGTACACTATATCAGATCCAAGAACTCCAAG ACCATCTGGTTGATTCTCCCTGCCTAGCCAATAAGAACTAGAGGAAGACTTCCCAGGGTC ACATATCAAGAGTCATACTGCAAAGTATAGAAGCTAGCCCTTCTTATATGACCTTAATTA TGATACTAATTAAGTTCAGTATGTCTATTAAGAATCATCTCAAAGATTTCAATGCTAGTG AATACGGCTATGATTTCCAACTCTAATAATTCGTGGTTATAATTATCTAGGATTGGAGAT CAACTGATGACCTTACCATAAAAGACCAATATTCTGCCACCCCTTAGGTAATGAATCTTC CAATCCAAAGTGCTGATGACAACAGCACCCTAGTACAGGTTGAGTATCCCCTATCTGAAA ATCTGAAATCCGAAATGCTCAACAATCCACAACTATTACACATGCACGAAGCTGACACGA AGCTCAAAGGAAATGCTCACTGGAGCACTTTGGATTTTCAGATTAAGGATGCTCAATCAC TAAGTAAAATGCAAATATCCCAAACCCCAAAAAATCTGAAATCTAAAGCACCTCTGTTCC CAAGCATTTTGGGTAAGGAATACTCAACCTGTACCACAATATATATTTCTTTTCAACCTT CCTAGACAGAGAAGAGAGTAAAAGTCACAAGTCAGAAGAAAGTAAGGATAACAGAGAAAC TAAGAAATAAGTTTTTTTAAAAAGTTACCTGTGTTAATGACTTTAGGGATAGGATCAATT TCTTCATCTACAACAAAAGGTTCTGGCCTGGGGAAGACTTGTACATCAGCAGTTAGGTGG CCACACTTGAGAACAGCATGGAAAGGCGTATATGCCAAATCTATCAGTTTTCTAGAATAT GATAATTAATAGTTATAGGAAGAGTAATACGATACATATGAAGTTAATTTTTCAGGACGC AAGGGTTGTTTTCCTTTCAAGTTGGTTCCAAAACTAAGATCTGACCATCTGTAAAACAGA ACAAAATCTGACATTTTTGGTGAGGAAATTTCAATTCTGAAAAGCCCAAGAGCAAGTTAA TTTGAAATTTTGCTGAGTCATTATAAGGAAGTCAGTATCTACAGACAGTATAGATTTACT TTAAAAAACCATTACTACCCATCACTTTATCTGAAAAATGTACAACTTGGGGAAAATGAA ATGACACAATTAGGAACAGTAAAACAGATAGTCTTCCTGGATGTCAAATTATAATACTGG ATTGTAAAGAAGGCAAAAGAGCTCTAAGCATATACTCACCCAAACATAGACTGTACATTC TTCAAGCACAGGGGGCCATCAATAGTAAAAATCTGCCCTTCACCATTGTTTAAATCTATG AGACGTTCAAGGCATTCCAAGGAATCGGTGCTCTGGAGCTATAAAGCAAAACAGATGACC CTTAAAGTGGCTGGCACAAAATGCCAGATTATTCTCAGCTCACCAAGGTCAAAGCCATTA CGATAACATAGGCAATAAATAACAGATGATTTTTTTAATAGCCAATGTGAGAAGAAAATA ACAACAACAATTTTGACTCAAGGTTACCAAAGAGGAATGTTACGTAAAATAACACAGGTA GAGCTATTTCATTCAGGAGTAGTTTTGCAAAGATTCTCAGAGGTGACCACAGTATTTACA CAGCATCTTCCCTCCAAAGTGTTTCTAACGTCTTTTGGTGAGAACCATCATTATCTACAT TTTACAGAGAGAAAAACTGAGGGGAAAAAAGGTTAAATCACCTTCCCAAATGAATGGGAA AACCAAGAATTTAAGTGTTTAATAAAACGTGTATCAGAATAATGTTACTTTACTCTTCTG TCAAAGTCAAAGCACACTCTTGTCAACATTTCTGGTGGAATGGACATAAGAATTCTATAT AAGGGAAATGAACAACACCAAAAAGAACACCTTGACCCTTTATGCACCCATCAGCAGGAT GGATAACAACTCCAGCTATGTTCCCCAGATGAGGCAACACTCTGAAATTTCAAAGAACAT TTGAGACCCAGAATCTTTTCAAATAAAATACCAGCCTCAGCTGAAACCAATGGAGTTCAA TGCTACAGTATATACAATATAGCACTAGTGGTATATACTGAAAAATAAACTAAGCTGTAA AATATGCCTAATCAAACTAAAAACTTAGCAAAAGGTATTACCTCCTCCAAATTCGCCATG CACATGATATATAACTTAGATGGGAAAGGAAAAGGTAGTGGAAACCTGTTGCTCTCACTT CGTTGATTTTGAGTGGCTAGGGAATGTCGCAGTGACCCTCTACCAATGCCAAGACAGCCG TCTGTCACCAGGACAACCTGTTTGTAAAAAGAGAGAGAGGAGGTTGTACATTAAATTACA TATTTAACGCAGTCCCATTTAGCAGTGTTTTCACTGCTAGAAAGGGGCACCAGGGCTGGC TATGGTGGCTCAAGCCTGTAATCCCAGTGCTTTGGGAGGCCAAGGCAGGACTGCTTAAGC CTAGGAGTTTGAGACCAGCCTGGGCAACATAAGGAGACCCCATCTCTAAAAAAACTTAGA AAAAAAAAATTAGCCAGGAGTGGTGGCATGCACCTGTGGTCCCAGCACGTTGGGAGGCTG AGGTGGGAGGATCACTTGAGCCTGGGAGGTCAAGGCTGCAGTGAGCCATGGTCACATCAC TGTACTCCAGCCTAGGCAACAGAGAGACTCTGTCTTTTTAAAACAAAACAAAACAAAACA AAACAAAAAAAACAGGCCTGACATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGG CCAAGGCAGGCAGATCACTAGAGGCCAGGGGTTCAAGACCAGCCTAGGCAACATGGTGAA ACCCTGCCTCTACAAAAAATACAAGAATTAACTGGGCATGGTGGTGCGTGCCTGCAGGCC CAGCTACTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCTGGGAAGTCGAGGCTACAGT GAGTATGCCACTGCAGTCCAGCCTGGGTAACAAAGTGAGACCCTGTTTGGAAAAACAAAA TAAACCCTCAACCTGGCCCCGCAAAAAAAAAAAACAACAAAAAAAGGCACGAGAAAATTT TGTGAGGTGCTAGAACCCCACTCCACATTATAGGATAAAGAATACTATATCTTAATTGTA GTAGTGGTTATATAGGTGTATACATTTGTCAAAACTCAGTGAACTGTATACTTAAGATCA ATGTGTTTTACTCTATTTCATCTAATAAAATATTTTTTAAAAGCTTGCCTCTGAACACTT AAAAAAGGACAAAAACATTCACAACCAATTCTTACTTAATTGTATTAAAACTAGAACCCC AACTCTTAGATAAGGAGTTGGTACCTAACATAACAATGTCAAATATGGAATGAAGATTCA TTTCACATGTGCTCCTAGGAAGTACCAGCACAGTAGTCTGAACTTTGCCACTTTATTTTC AAAGATGACAAACTCTACGCCTGGTCAACTAAAATGACACCTAGTTAGAATATGTATTTA TAAAGGCTATTTAACCAGAAATATATAAGATCTTTAAAACGCATTCTTAACCTGTAATTT GAAAAAACCAACAAAATATACCAACAATGGATAGTAATTGCAAAATCATTTTCCTTTTCT TCATTGCTTCAGAATGATCCTGTGGTGGACAGACTTCCCATGCATCCCAGGAGAGGATTA TTTTTGCTCTCCCTAGCCTAGTCCAGTAACTTGATAACAATAGGCCATTAAGGCAGTATT TTTTTTTTGACAAGGAGACTCACTCTGTCACCCAGGCTGGAGTGCGGTGGCGTGATCTCA GCTCACTGCAACCTCCGCCTCCCAGGTTAAAGTGATTCTCCTGCCTCAGCCTCCCGAGCA GCTGGAACTACAGGTGTGTGCCATAAAGCCCACCTAATTTTTGTATTTTTAGTAGAGACG GGGTTTCACCATATTGGCCAGGATGGTCTCGAACTCCTGACCTTGTGAACCGTCAGCCTC GGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCCTTAAGGCAGTA TTAAGTGGTGGCACTGTGTGAAATATCAAGATTGGCACTTACTGATAAAGCCCAAGAATG CTTAATAGAGGTCCCCTGGAAGGATGTCATCTTTTGGCATGACAGTCAATTGACTACAAG GCAATTTCCTTTTCTAGGTACCAAGAATTGCTATACAATGATTTACCTCCATCGGCTTTT TCAGATGCTATGGGATAATGAAATATTTCACGTAATGTCAAAATGAAACAGACTTTACTA AATAATAAAGACACAGTACAGCTGTCTAAAACCTTGGTTAAGGCTGGGTGTGGTGGCTGA CAGCTGTAATCCCAGCACTTTGGGAGGTTGAGGCCAGAGGATCACTTGAGGCAAGGAGTT CAAGACCAGCCTGGCAAACATGGCAAAACCTTGTCTACTAAAAATACAAAAATTAGCTGG GTGTGGTAGTGCACTTCTGTAGGGCGTGATGGCACACTCCTGCAGTCCCAGCTACTCATC AGGTGGCTGAGTCATGAGAATCATTTGAGCCCGGAGGCAGAGGCTGCAGTGAGCTGAGAT CATGCCACTGCACTCAAGCCTGGGCGACAGAGCAAGACTCTGTTTCAAAAAAATAATAAT AAATAAAAAACAAAATCTTGGCTAAAAATTCCACTTTTTTTTTTTTTTTTTAAGACAGAG TCTCGCTCTGTTGCCCAGACTGGAGTGCAGTGGCACGTTCTCGGCTCACTACAAAATCCA CCTCCCAGGTCAAGTGATTCCCCTACCTCAGCCTCCCAGGTAGCTAGGATTACAGATGAA CGACACCACACTTAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGC CAGGCTTGTGTTTAACTCCTGACCTCAGGTGATCTGCCCACCTCAGCCTCCCAAAGTGTT GGGATTACAGGCGTGAGCCGTCGCGCCTGGCCAAAAATTCCACATTTAAGCAAGTTTGTT TTATAGTAACTGATTATAAAAACAATAACCAGTAAACACCACCTCTACTACAATGTTTTT TTTTTTTTTGAGACGGAGTTTCTCTCTTGTTGCCCAGGGTGGAGTGCGATGGCACAATCT TGGCTGACCAGTGCAACCTCTGCCTCCCCGGTTCAAGCGATTCTCCTGCCGCAGCCTCCT GAGTGGCTGGGATTACAGGTATGCGCCACCACGTCTGGCTAATTTTTTTATTTTTAGTAG AGACAGATTCAGGCTTGGCCCCTTGCCCTCACGTTGTCTCAAATTCAGATTCTTCCTTTT TTTCAAAAGAAGAAAATCATAAAAGTCAGAAGTCTGCATGATGCACAAGGTCTGGTTCTT AAAATCTGAATTTCTCCTCTAAAACCAAAGAAGAAATAGCAAATGAAACTGTGCTACTTG CTAGCTTTCAGTTCAGAAGATACTGACAACAAAACTTCATTTATTCACTATAATGTTAGG AAATAAGACATCCTATATGCATGGATTTACCAAAATAAGTAATGCCTATAAGCTGAGATG CCATAAAAAGCTTTTTTATTTCAGAAAAGAAATTGATCAAAAGGCATCTATTGATTTCTT CAGCAAGTATCCACTATATTCTATAAAACAGGGAGGTTTTCACAAGAAAAAATGTTTTTG TTGTTTTCTAAAGGTGAGTTTATTGAGATATAACTTACATGCAGTAAAATCACCCTTTTT AGTATACAGTTCTATGAGTTTTGACAGTTGTATTCAGTCGTGTAACCACCCCCACAAACA AGATAAAGAATAGTCCCAACACGTCCCAGATTCCCTCCTGCTTCTTTTGAGTCAATTCAT ACCTTTCCCTGACTCCCAGGCAACTACAATCTTATTTTTTTTAAGACAGGGCCTCACTAT GTGGTCCAGGCTGGTCTTGAACTCCTGGGCTCAAGTTATCCTCCCACCTTGGCCTCACAA AGTGCTAGGATTATAGGTGTGAGCCACCATGCCTAGCTACAATCTTTTTTTTTTTTTATT AATAAATAAATACTAGTGATGCTACTGACATTACTGAGGAATCCTTTGTTTGACCCCATA ATGAAAAGTCACACACCAGGGTCCAGCCAACCATGGCCCACAGGCTAAATTTGGCCCACT GTCTGTTTTTGTAAATAAAGTTTTATTTAAACACAGCCCTACCCATTCATTTACTTATTA TCTATGGCTGCTTTCATGCTATAACAGCAGAGCTGAGTAGTTGCCACAGACACCTACAAA GCCTAAAATACAAAAAAACTTGCGGACTCCTGTTGTAGACTATTATGATTTTTCTTTTAG CAATGTTTCTGCTTTTTCCTTCAAAATATGCTACTACTTTTCAAAAGTATCTGTATAGAA CAAATTTCCAGTTATCTTTTTCTGCTACTACTCTGCTCTGATTTGATACTAATGTGGCCT ACTGTGGAGTCTAAGTAAAGAGCAACAGACTTTATGTTTGTTTGTTTTTGCCACACAGTC TCGCTCTGTCGCTAGGCTGGAGTGCAGTGGCGCAATCTCGGCTGACTGCAACCTCTGCCT CCCACGTTCAAGTGATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGGACTACAGGTGCACA CCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTCACCATGTTGGCC AGGATGGTCTCGATCTCTTGACCTGGTGATCCGTCCACCTCAGCCTCCCAAACTGCTGGG ATTATAGGCATGAGCCACCGCGCCTGGCTAGATTTTATGTTTTATACTCCTCACTTTTTA GACAACTCAGTTGAGATGGTTAAGTTTGCTGAATAAAGCTGGGCACAGTGGCTCACCCCT GTAATCCCAACACTTTGGGAGACGAGGTGGGCGGATCGCCTGAGCCAGGAGTTTGAGACC AACCTGGGCAATATGGCAAAACCTGGTCTCTACAAAAAATGTAAAAAATTAGCCAGGTAT GGTGGCATTTGCCTGTAGTCTCAGCTACTCAGGAGGACGAAGTGGGAGAATCACCTGAGC CTCGGTGGTTGAAGCTACAGTGAGCCATAATAGCTCCACTGCACTCCAGCCTGGGCAACA AAGTGAGACCCTGTCTCCAAAAAAAAAAAAAAAAAAAAGTCTGCTGAATAATTGCATTGA GATAATGAAGACAGGCTATATTATACTGATGTTTACAATTTTATCACTCAAAATTATAAT GACCCCTTCCAGGGATTGTAGTTCAAAAATTCCACTGTGAGCCCTTTGTGTTTTATATAA CAGTACTAGTTTGCAATAAGTCAATTTACTAGGAGGATGCTTTCCTTAAGGCATAACTTT GCTGCTTTCTGAACACATTAGTGTTGATTTAGTACCTTCACTTAAGAAGATACCAATAGT GTAAAATGTAGTTTGTAGAAATTACAATGCATGCTGTGTCAGAGCCTGAAGAAAATCGAA GCACCTCAGTGGTTAATGTTGTTAACTTAGGGCAATGAAAAAGAATTGATCATTACCTGG CAAGGAATTGCACCACCCCATTCTTGCTGAACGATATTGCAAACACCAACTAATGCAGAC TCCAAGCAGGTTTTGTCATAATCATCCATATTACTTAGTGCTTCCTTATTGAATAAAAGA TAAAATTGCTAGTTACTCTTTAGTTTTAATTAGGTATTAGAAAACAACATAAATTGTTCA AAGTATGAATGTTACACAGGGGACACTGATGTATCTGAGAGCACCAAAGCATAGCTTCTT AAAGAAAAATGCTAGAACAGACTTCTTCAACTATTAAAGATAGTTAAAAGAATTCCATTT ATTCTATCCTCTTATCAGGTAAGAGTGAACAGTCCACCAAGTTTACATTTTTGTTAAGTG GACTTTGAAGGAAAAAATTAAAAGGAACTTTTAAACACATCACAAAAATAATAACAAAAT CTATTGAATATTAACTATGTTCTAAACACCATCCTAGGCACTTTTATGCATTTAGCTATC ACAATAAAACTATAAGGTATAGATTATTAACCCTATCTTTAAATGAAGTAATTAAGGTAT AGAAAGATTAAATAACTTTCCCAGGTCTCATGACTAAGGTGGCAGAACCTGGATTTGTAA GTATGCAGTCTGACTTCAGGGCTCCTGGTCTAAAACATTACGTCTCACTCCTTATATAGC AATTCTCTAAATTTCAGAACTGCAGAACATCAGAAATCCTTAGTTTATTCACCTGTAAGA AAGTCAGCATATATACCAAAAGTTTAATATCCTTTTACAGGAAAAGAAATTTAAAAAAAA TTTTTTAAGTCACTAATTTTTTTAAAAAAAGCTTTTAAGTCACTTAAAAAATCTGAGATA AGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGACGCCGAGGCGGGCGG ATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTA AAAATACAAAAAATTAGCCGGGCGAGGTGGCGGGCGCCTGTACTCCCAGCTATTCGGAAG GCTGAGGCAGGAGAATGGCGTGAACCCGGGGGGCGGAGCCTGCAGTGAGCCGAGATCGCG CCACTGCACTCCAGCCTGGGCGACAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAA TCTGAGATAATAAAAGGAATTATTTAACAAAATTTTGTTACTTACATTAAAAAATTCAAA CTCTATTGATCTTGTATTTCTAAACCACCTAACAATTGTTAAAACTGTTCAGTTTAATTC CACAAATGCTTCTTCTTTTTTTTTTTCCTTCTTTTTATTAAAAATAGAGACGGGATCTTG CCATGTTGTCCAGGCTGGTCTCAAACTCCTGGGCTCAAGTGATCCTCTCGCCTTGGCTTC CCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCCACAAACACTTCTTGACT GCTCACTATGGGTAAGACACTGTGTTAGGCACTGCTGGAAATATTATGAATATTATGATT TAGAGATGTTGTCAGAAAGTAAATTCTAACATAACACAGAAAACACCTTTGAAAGATAAT ATCTACCAACTGAGATTTAAAAATTATAATTTATTGGTATCAAAATCAAAGCTATTTGTT GGAAAGGAAATATCATTTTGAATTACTCTAGAATAAGAAAGGGCTATTTTTTCATTTCCT CAAGTTTTATGGGAGAGTAGAAAAAAATTAAGTGTTGAGCCTAAAGATCCTAAATTTTAG GGAATGGAACACTACATCCTGAGATGCTCACTTTTCCACAGAGAATTCCAGAAAACCAAG AGAGGAAAATAAGGGAACAACTCACAGCTGTAACTCATAGCTGTACCGAAGAAACAGTAG GCATAAGACCTACTGGTTGTGAATTCTTGCTGTTTAGTTACACATATTAAGTACTCATAG ACTTATTAAATAATGCCAAAGTTCTAAATATTCAACGCATTATAACACTGTTTTCCTCCC AATAAATTTAGGCCCTGTACATACAATAACTTACTACATTTTGTACCTGTAGGGTATTAT AATCTCTCGTGAAGGGGACCATCAACTCCCAAAGTGATGAAAAAACCACAAGTGCTGTAA ATTCAAGCTTGTAATTTGTGGCCATGTGCTCAAACAGCATCGTTAAACCATGGGCTGCTA GGTGCTTACGCTGGTATTCCTCGGACCCCTCAATAGACACAGGTCGGGTCATGGAAAGGG ATACATCCATTACCACCACTGTCGGCATGATGAAAATGATCCCAGTGTTCCCAATCAGAA TGCAAACAGACAGCTATAAACGAAGAAATGCTGCAGAAAATAAATACGTTCTTACATGTC ATGGAGAGAAAATAATATTTTTCACCATAACTTTAACTAACTTCTCAGAAATTAGCAGAG GCAAACACCATTTAAGTTGAGGTGAGGAATAATCTGTAGAGAACTCAGTGAGAGGGAAGT GAGCAGCTTAGTTCATTGTAAGGACCACTCTTAGAATCACCCATTAAGTGACCATAAATC AAGGACCATCTAAATATATCTACTGGAAAAAAAAAAGCCCTGCTAAATTCAGGTAGCCCT TAACTTTCACACATTCGACTTTTATGCAACTTAATAAACTCCCACATCTCCTAACACTTA ATTTACTGAAGAACATTTCTAGTTGTCATATGTTGGTGCTATTTGACAAACAACCATTGT TTTTTGGCACTGTCACAACCTTTTTGCAGTATTACTGCATGTGTTTAATTATTTTGTTGG TTGGTGCTCTTGTTTTAGTAAAATGAATGCCAAATATAAAAATGAAAGGACTAGTAAAGT CATAAACCAAATTAGACAAATTGGAAATCATTACACATAACAAAAGTAATAAACTGTCAG CCTCAGTAGTATTCATTGTACATAAACTGGCCAATGGTGCTTCAACTGTGAAGGAAAAGA ACAAAATTAAAGAATATGTAAGGTCGGGCACAGTGGCTCATGCCTGTAATCCCAACACTT TGAGAGGCCCAGGTGGGCGGATCTCTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATA TGGTGAAACCCTGTCTCTACTAAAAATACAAAAATCAGCCAGGCATGGTGGCTACTTGGG AGGCTGAGGCACGAAGATCCCTTGAACACAGGAGGTGGAAGTTGTAGTGAGCCGAGATCG TGCCACTGCACTCCAGCCTTCCAGCCTGGGTGACAGACGAAGGCTCCATCTCAAAAAAAA AAAAAAAAAAAAAAAAATTTATACAGCTGGAATTATCTCATGAAATTGGGTAGAAAAGTC AAAATGTACAAATGGAGTTATTCAAAATTATGGATTGAGAATTAGCATAAAGAAAACATT TTGGTGCTCAAAAATAAAAAAGTTTACAGATACACAGACCTGCTCATGGGTATATAGCCT GCTGCTACTCTATTATTAAGCAAACTGTAGGCTACTGACATGATGAAATATCATAAAACT ATAAATAAATGACATATGTACTACAGATATCAGAAATACTTATAGAAAGCATTAGTAACT GAGAAAAGCAGGCCCCAGAACTGTATTATACACTGCTTACAACTTCATAAAAATCATAAT GCAAATATACAATTAGAGAGATTAGGTGGATATAAACAGGTTAGAAATTTAATGTTCACA ACTTTCTTTTTTGGGATTAACTTCAAAACATTTAACAGTAGCCAGATTACTTGTTTAAGG ATGGTGCCCAGCTGCAAATGTGTCATATTCTAAAATTCCATTTGTTCTTTTTTGTTTTTG AGACGGAGTCTTGCGACATCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTCCGCTCA CTGCAAGCACCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCGG GACTACAGGCGCGAGTAGCCAGGACTACAGGCGCGTGTCACCACACTCGGCTAATTTTTG TATTTTTAGTAGAGATGGGGTTTCACCACATTGGCCAGGCTGGTCTCGAACTTCTGACCT CGACATTGGCCAGGCTGGTCTCGAACTTCTGACCTCGTGATCCACCTGCCTCTGCCTCCC AAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCAAAATTCCATTTGTAAGTAG GCTGTTTCGAACTCAGAATACACTGGTTCATGGAAACAATGTTTACAACTCAGGTTGTAA GCATAGGCGTAAAAGAAGAAACTGAAAGTTCCTGAAGGATGGTTCACTCAAGCAGTATAG GCCCGACTGAAAAAAAAAAAGTGAGGTCCTGCACAATATTGGTTCAACTACACTATATTA GACCATAACATACGCTCACTAAGGGCAGGGACCATGCCACATTTTGCCCATGATGTCTCC TCAAAACTTATCACAGTAACTGGCACATAGTAGGTGCCCAACAATTTGATAACAACTGAT GAACTACCCCTAAATCACCAGATATACCATATATTATTTAGCAAAATACATTATAAATGT TAACTCTGGACACCAGAAACACATTTCCTCTTCTCCTCATTCAAGCAGACATATGGGGGA CTCCCTCACGTCTGCCCAGCTCCTGTGGTAGTCCCATTCATGCAGGGAGGCCTTTTTACA AGTTGAGGATCATGAGGAGTACTGCCCTCACCTCTTAGGAGAATGGGAGGAAACAGTTTA CACAGACTTAGATCAAATACAAAAAAGCACTTTCAGCCCGTGAAATCTGCTGTTGACAGT GATGACAGCTGGCAGTCTTGCCTTCTCTGAAGACACCTCTGGAGCTGGCTCTTTCTCCCA AGTGATGCATTTGTGTCGACTCCCAAATGCACCTCATTAACAGTTACAAAGTCGTGGGAG ATCAATTTAGTACTCAGGTTGGAGTAAAGGAGGGAACTGAAAGTTCCTGAAGGATAGTTC ACTCAAGCAGTATAGGCCTGATTAAAAAAAAAAAAGGCCAGGCACGCCTTTAATCCCAGC ACTTTGGGAGGCTGAGGCGGGCAGATCACCCGAGGTCAGGAGTTCGAGACCAGTCTGACC AACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGATGTGGTGGCGTGC GCCTGTGGTTCTAGTACTTGGGAGGCTGAAATAGGAGAATTGCTTGAACCCAGGAGGCAG AGGTTGCAGTGAGCCGAGATCGCGCCACTGCTCTTCAGCCTGGGCGACAGAGCGAGACTC CGTCTTGGGTGGGGGGGAATCCCTGCCCACCACAGTCTACCAATTTTGTGAGCACAACAC TATGTATTCCTCACTTGGGTGGATTCTGAGCCCCCAAGTCTCCCACCCCCACCCCCTTCC CACGTGTACTGTTCAAACAACTAGGGCTCTTCTTTCTCAGGAACAGTCTGAGAAATAGGC CCTAGCCACCTATTTGGCCTTGAATACCAAGTGTCCATCAGCTAGACGTTTGTAATTCTT CCCTGAAGGTGATAATTAGCTCATTCATAAAGAACTGATTCTCAGCAGTCTCGCTCTCAA AGCAGGATTCTACCTGAATTTCTAGTGCCTCACCTGCTCTTTGGCTTTCCCGTCAGCCTC CGGGAGTCCCTCCCCAGTTCTCAGATATAATTTCATCTCTAAAAGTCCAGACTGAAAATC ACATCTGGGAGATGTATTTTTACCTTAAAAATCAGTCAAGAAAATGTGGGATCTGGAAGT CTCTCTTGGAAAGAGGGGGCAGAGGGGAGCTGAGCAGAGGGCGAAATCGTGCAGTTTACG CGGAGCTGGGGACCCCGAGCCTCAGAGCGAGGGGAGGCCGGGAGCAGCGCCCCGGAACTG GCGCCTCACAGACAGCGCGGGGCGGCCGCCACGGTGGCGGGAAGGCCAAGCGCTGGCCCT GGGTTGTTCTTCACCCATAACCCCTTCACCTGTAACCCCAACAAGCAGCGAAAGGCAGTC CCGGGCCCTCGGCCTCCCCACTCACCCCGTGCCCATCGCCGGACACAGTCCGTCGGCATA AACTTTCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAACTATAAGGCCGCGC GACAGAAGGGAATCCGGCGCCTGCACTCCGCGCTGGGCGGGGCGGTCCTTGGAGAGCTTC AGGGTCGCCCGGGCAGGGTTCTGGCTCATCCCGGAGGGACGCTAGGGGGCGCGGCCT bcftools-1.21/test/csq/ENST00000573314/ENST00000573314.fa.fai000066400000000000000000000000221467060157400215270ustar00rootroot0000000000000015 32577 25 60 61 bcftools-1.21/test/csq/ENST00000573314/ENST00000573314.gff000066400000000000000000000073321467060157400211600ustar00rootroot0000000000000015 ensembl_havana gene 21 32557 . - . ID=gene:ENSG00000138614;Name=VWA9;biotype=protein_coding;description=von Willebrand factor A domain containing 9 [Source:HGNC Symbol%3BAcc:25372];gene_id=ENSG00000138614;logic_name=ensembl_havana_gene;version=10 15 ensembl_havana NMD_transcript_variant 21 32404 . - . ID=transcript:ENST00000573314;Parent=gene:ENSG00000138614;Name=VWA9-001;biotype=nonsense_mediated_decay;havana_transcript=OTTHUMT00000256861;havana_version=3;transcript_id=ENST00000573314;version=1 15 havana exon 21 927 . - . Parent=transcript:ENST00000573314;Name=ENSE00001522374;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001522374;rank=12;version=3 15 havana three_prime_UTR 21 927 . - . Parent=transcript:ENST00000573314 15 havana exon 3222 3287 . - . Parent=transcript:ENST00000573314;Name=ENSE00003529647;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003529647;rank=11;version=1 15 havana three_prime_UTR 3222 3287 . - . Parent=transcript:ENST00000573314 15 havana exon 6038 6156 . - . Parent=transcript:ENST00000573314;Name=ENSE00003589575;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003589575;rank=10;version=1 15 havana three_prime_UTR 6038 6156 . - . Parent=transcript:ENST00000573314 15 havana exon 12866 12999 . - . Parent=transcript:ENST00000573314;Name=ENSE00003515554;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003515554;rank=9;version=1 15 havana three_prime_UTR 12866 12999 . - . Parent=transcript:ENST00000573314 15 havana exon 14696 14840 . - . Parent=transcript:ENST00000573314;Name=ENSE00003647901;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003647901;rank=8;version=1 15 havana three_prime_UTR 14696 14840 . - . Parent=transcript:ENST00000573314 15 havana exon 17001 17093 . - . Parent=transcript:ENST00000573314;Name=ENSE00003653848;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003653848;rank=7;version=1 15 havana three_prime_UTR 17001 17093 . - . Parent=transcript:ENST00000573314 15 havana exon 19589 19731 . - . Parent=transcript:ENST00000573314;Name=ENSE00003663634;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003663634;rank=6;version=1 15 havana three_prime_UTR 19589 19731 . - . Parent=transcript:ENST00000573314 15 havana exon 20140 20258 . - . Parent=transcript:ENST00000573314;Name=ENSE00003617560;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003617560;rank=5;version=1 15 havana three_prime_UTR 20140 20258 . - . Parent=transcript:ENST00000573314 15 havana exon 21042 21197 . - . Parent=transcript:ENST00000573314;Name=ENSE00003657631;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003657631;rank=4;version=1 15 havana three_prime_UTR 21042 21197 . - . Parent=transcript:ENST00000573314 15 havana exon 26397 26504 . - . Parent=transcript:ENST00000573314;Name=ENSE00003616634;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003616634;rank=3;version=1 15 havana three_prime_UTR 26397 26504 . - . Parent=transcript:ENST00000573314 15 havana exon 28427 28710 . - . Parent=transcript:ENST00000573314;Name=ENSE00003667579;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003667579;rank=2;version=1 15 havana three_prime_UTR 28427 28710 . - . Parent=transcript:ENST00000573314 15 havana three_prime_UTR 32064 32225 . - . Parent=transcript:ENST00000573314 15 havana exon 32064 32404 . - . Parent=transcript:ENST00000573314;Name=ENSE00001522376;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001522376;rank=1;version=2 15 havana CDS 32226 32399 . - 0 ID=CDS:ENSP00000458470;Parent=transcript:ENST00000573314;protein_id=ENSP00000458470 15 havana five_prime_UTR 32400 32404 . - . Parent=transcript:ENST00000573314 bcftools-1.21/test/csq/ENST00000573314/ascii-art.txt000066400000000000000000000007271467060157400212720ustar00rootroot00000000000000 rev strand c .. CDS u .. UTR . .. outside the transcript 32388 32399 89012345678901234 ccccccccccccuuuuu.... GTCCGTCGGCATAAACTT-----------------TCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt G-----------------TCCGTCGGCATAAACTTTCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt bcftools-1.21/test/csq/ENST00000573314/ascii-art.txt-l000066400000000000000000000007271467060157400215230ustar00rootroot00000000000000 rev strand c .. CDS u .. UTR . .. outside the transcript 32388 32399 89012345678901234 ccccccccccccuuuuu.... GTCCGTCGGCATAAACTT-----------------TCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt G-----------------TCCGTCGGCATAAACTTTCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt bcftools-1.21/test/csq/ENST00000573314/incorrect-insertion-overlap.txt000066400000000000000000000010101467060157400250460ustar00rootroot0000000000000032388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT 32388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift&NMD_transcript|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT bcftools-1.21/test/csq/ENST00000573314/incorrect-insertion-overlap.txt-l000066400000000000000000000010101467060157400252770ustar00rootroot0000000000000032388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT 32388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift&NMD_transcript|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT bcftools-1.21/test/csq/ENST00000573314/incorrect-insertion-overlap.vcf000066400000000000000000000011411467060157400250120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 15 32388 . GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT . . EXP=frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT;type=ENST00000573314:65903458-GTCCGTCGGCATAAACTT-GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT .. this is incorrect, see ascii-art.txt bcftools-1.21/test/csq/ENST00000580206/000077500000000000000000000000001467060157400166455ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000580206/ENST00000580206.fa000066400000000000000000003717651467060157400210160ustar00rootroot00000000000000>18 18:14728173-14854038 ATCTATGCATTCAGAGTTGTGGCAGGAACTGCATATGAATAAAGGAGTCCCTTTACTACA TTCTAAGGAAGAATTTGTATGTTCTATTACAGACAATGCTTTGTTCTCAGCCATGTCTGT CCTGATATGGCTATCCAGATAGACTTATCTTCCAATTCCTCTGACTCCGCAAATCTTTTT TTGTGTCCTCTGGAATTCATGGCCAGTCAGCAGCATAATTCTGTATAATCTCAATATATT TATTTTATTTGAATGTTGCCCTAATAGGAGATTGTGTTGAAGACACAGCTTGTTCAGCAG CTCATATCATTCACATCTCCCTATGCTTTCCTTCAATCTAATGTGAGTTCATTTTTTAGC ACTGCAGGTCCAAAATGTTGAATAGATAGTTCGACTTTCAAGATTTTTAGATGCCTTCTT CCGCCCCTTTCAATTGGCAAATGCATCATAGCAAAAATCTGAACAGAACATCTAATTTAT GTTCGTGTGCTTCCCTTCTTTCTGGAGTCTTGCATCCTCAAGTCTCTGCTGCTTGGTAGC TCTCAGGTGCCCTCTAACACATTATCTTTCATATTTTACCCAGCCTTACTAATTAGTCTA GCAAGAGGGATGGTCATATTCAAGTTCATGTACTATAGCTAGAAGTAAATATCCTTGTGT TAGCTATTAAGATTTGACGAGGCATGAGAAATAAAGATGCAAAATTGTCCTCATTTACAG ATGATATGATTCAACACTTTCAGTATACAGGAGCCAAGACTGAAAAAAATGACTTAAAAC ATGATGATAAATTATTATGATAGGTGAATAAAAAACAAAAATAAATCGTTTGTAATGTAT ACATTATATAATTAGAAAACACCCTATTTTGCAAAGCAAAAAACTTGAAACAGACCTCAC AATGTGTACGATTTTTAAAGGGAAAAATTATATACTATTGGAAGATTTAAAGTAAGTTGT TAACAAATAGTAAGCATGTAATGTCTTGTAATAAAAACACAACACCATAATGATGACAAT TCTGTCAATATTAATATATAAATTTAAAAGAACAGTAAAATAGAAATGTTTTCTGCAATC ACTGTGAAGTCAAGCCCAAATTTTATGTAGAAAGATAAAACAACCAGAAAATTCCTAATA AGGCGGATGGATAGCCAGGAGGAACAAGAATGAACATATAGGAAAATATTGTATAACCTT ATTAAAGAATTTTATTTAAAGAAGCAACTTGATCCTATTCCCATTTTAGTAAAATCACTG TAATACATAGAAAGGATTATGAACCAACAACACTGAGGAGAGAAGTTAGCTTTTTCAGAG AGAAGTTAGCTTTTTCAGTGATACTTTCAAAATCATAGAATTCTGAATTAGCAAAATAAC AGTGAGGCAAGAGGGAGAGATTTAGTAGATGTTATCAATCATGATACTCTTAACACAGCA GTAGCTGCCACATAGAGTGTTTATATAGTTAGGTGCTGTGTATATCTCAATGTATTTAAC CCACACAAAAACCTTTGTGTTGAGTTCTACTTTAATTTCAATTTGGCAGATGTGGGAATT AAGGCACAGAATTATTGCATTAATTGCCCAAGATCATGCAGTTACTTTAAAAAAGCATGA TTCTGGCTTCAGATTCTGGGATCGCACCCTCAAAAGTATACAATTTCACTAAGAGTTTCT GTGACATCATTGTCTGTGGCCTGTGACAATGTCAATGAACTTGTGTCTGACTTGGGGTGT GGGTGAATTGTAGTAGTGCCGTGTATAGAAATATGTGCACACACACACACACATACACAT ACACACACACACACCCCAACAACTAAGAATCAAAGAACTTGGGTCATCTTTTGAGAAGCA TGATTTGAATGATGTCTCAAAAGCAGTGTATATATAAATCCAGCTATGATTAGTGATATC TGAGCTGGCAGAAGAGACCTGGGAATTATCAGTCCATCAATAATAATTAAAGGCATGAAA ATGAGATAAAAGTCATTACAAATAAGAAGCAATTTGAACTGTCACTGATCTCTAAATAAT AGACATATTGTAAAGAACAGGCAGAATAAATTGAATGAAGAGGAACTGAGAAGGCATATC CAGAGAGGGAGAGAGAGAGAAAGAAAGAAGCAAACTCAAAGAAGTATGGTGTTCCACATG ATAATGTAAGTGAACAGAGTTTTTGAAGGTAAAATTCAAATAGACAACTGCCATGGTTTG AATATTTATATCAAAACTTAACGTTGATATTTAATCATCAGTGTAATGATATTGGGAAGT GAGGCCTTTATGAGGTGATTAGGCCAGGAGGGATCTGCCCACATGGGTGGGTTAAACAAC TGTTGAAAAGGGCATTCAGAAATGAATTTCAGCTCCTCTGTTCTGCCATGTGGGGAACAG TGTTCCCTCCCTCTGGAGGTTGCATCTTAGAAGCAGAGGTGGGGTCCTTATCAGACACCA AACTTGCGGCTGCCTTGATCTTAAACTTCTCAGTCCCCAGAACTGTGAGAAAAAAACATT CTGTTATTTATCAATTACCCAATTTCAGGTATTTTTTTTGTAGAAGCACAAAACAGACTA AGATAATAACTCCTATCTTTATTCTTATATAATTTTAATATGATTCTTTTATAAGATTCC CAAAATATTAGCCCTGTCATTTTCTCTCCGTTATTTACAGCAATTTTTCTTTAAAAAAAT TCAGCTTTTATTTTAAATACGGGGGTATATGTGTAGAAATGTTACATGGTATATTAGACC CACGTAATGAGCATAGCACCCAAGGGGTAGTTTTTCACCCACGTCCCCCTCCTTCCACCC TTTCCCCTTTCCCTAGTAGTCTACAGTGTCTATTATTTCTATGTTTATATCCATGTGTGC TCAATGTTTACCTCCCATATATACATTCTTAGTATGGGGGTACCATTCTTACCTGTAGGG CAACAGCAAACATTACTATCTGTGGACTTGCAGAGTCGTGGTTCCACTGGCGTGAAAACA CATTATTATTACATTAGACCAAGACCTAGTTTATAGCAAAGGAGAAGAGCAAGTGGGCCC ATGACCATGAGATGACGTACTTACCCATCCAGAAGCTGTCAGCTGGAGAGAGAGTTGAAA AGGCCCGCACAGCTAAAATGTCAGTTTGGAGCCAGTACTTTCTGAGAATTGTGTTTCATC ATCTAGGATGCAGCAGATAGGTTGAACAGAAGACCTTTGATGGCTCTGTGGCTCTAGTGG AAAGAATATATGCATTTGGAATCTAAGGTATGCAAAGAAGAATGGCGCCATTAATTAATA TAATAGTTCCCCCTTATCCTCAGTGGATCTGTTCCAAGAACCCCCTGGGGGTGCATGGAA TTGCAGGTAGTAACATATCCTATGTATACTAAGTTTTTTCCTATATATACATATCTATCA TACAGCTTAATTTATAAATTAGGAACAGCAGAGATAACAATAACTAATAATACAATAAAA AATTAAGATAGTATGCCAGTATTATTAATCTTGAGCTTTGGGATTACTGTTAAGTAAAAT AAAGTTTACTTAAGCACAACCACTCAATCACTAATAGCCTACTACTGACCAGAAGCCTTA CTAACAACATAAAAAGTAAATTAAAATATATTTTGTATGTAATTTGTATTATACACTGTA TTCTTAACAAAAAATTAAGCTAAATAACAGAATGTTATTAAGAAAATCAGGCCGGGCACG GTGACTCACGCCTTTAATCTCAGCACTTTGGGAGGCCGAGGCAGGCGGATCTCTAGGTCA GAAGATTGAGACCATCCTGGCTAACATGGTGAAACCCCATCTCTAATAAAAATACAAAAA AATTAGCCGGGTGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCCAAGGCAGG AGAATGGCGTGAACCTGGGAGGAGAAAATATACAAAATATATTTACTATTCATAAAGTGG AAGTGGATCATCATAGTGATCTTCATCTTTCTCATCTTCATGCTGAGTAGGCTTAGGAGG AGGAAGAAGAAAAGGGGTTGATCTTGCTGTCTCAAGAGTGGCAGAGGCAGAAGAGGTAGA TGAAGTGGAGGGAAGGTAGGAAAGGCAGTCACACTTGCTGTAACTTTAATTTTTAAAAAT CACATATAAATGGGCCTGTTCAGTTCAAACTTGTGTTGTTCAAGAGTCAACTGTATATTA AAGTTATTATGAATTGTCACAGAGCCGTTCATAGTGAAATGTTGTACATAACTTAAGTGT CAGATCAAGACTGCCTAAATAAATTAGAGCACACCTGTACAATGGAATGACATTTAGCAA AAAAAGGAGCTAGCCCTTTTTATAGAAGAATCATCAATATATATTTAATGTGAATAAAGA ATGGTGCTGATATATATATATAGTATGATATTAGTTTTGCAACTTAAGCAAAATATTTGT AAAAACATTTGCTTCTGTATGCCTAAAACCATTGGAAAGATTGACAAGAAACTAAGAACG TGATTTTATTTTGAGTAATAGTTGTACTGAGTGGACTGAGGATGATTTTCACTGAATAAC CATGTATATTTAGGTATCTGTTTAATGGTTTAGCTACTCAAAAAGTATATAAAGTTATAT CAAGGACAAATTATTCCAATGAGCAGGATTAAAAATATTTCTAACATAAATATTATAACT GAAATATTATCTACTTATTAAGAGACAAATAAATGACTAAAGTACTTCACTATTCTCTAA TATTTTGTTTGGACCAAAGAAGGAAATAATTTTAAAAGCAGTATCTTTAAAAAAATCTTA GTCTAACAAAGTACACTAAACTATTTGTTGCTTAAACTCCATCACTTTAAGTTTTACCTG TAAAGCCATCTAAATAAATACTTAAAGTTAGAGGGGGAAGATAAATAAGTAGCTTTTCAT CTGAATACATTACAGTTGAATTACAGTTGATCTTTAAATAACATGGGTTTCAACTACACC ACTCCACTATAGTAGATTTTCTTCAGCTTCTGTCATCCCTAAGACAGCAGGGCCAACTGC TTCTCTTAGCCTACTCAATGTGAAGACAATGTGGTTGAGACCTTTATGATAATCCATTTC CACTTTATGAACAATACATACATTTTCTCTTCCTTATGATTTTAATGTTTTCTTTAGCTT TATTGTTAAAAATACAGTTATATATATGTATATCATACAAAATATGTGCTAACTGACTTT ATATGTTATTGGTAAGGCTTCTGGTCAACAGCAGGCTATTAGTAGTTAAGTTTTGGGGGA ATCAAAAGCTTTTTGGGGATTTTCAACTGCTCCAAGGATGGTGCTCCCAACTCTATAGAG TTGTTCAAGTGTCAATTGTATTCTTGCATATTCTGTTAGTGCAGTAAGGTGTCCAATTTA GAATGCTAGGAGTTGTTACAAACTTTTCTATTTGACTCACCATGAATAATCAACTGGTAG CCAAATACTGATTATAAAAATCTCCATTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGT ACAGGTACTGAATACTTTTTATTACTATTAGTAAATAGACCTAAAGATTCCTCCCTGTTT TGCTGAGACTGTTAATTCATTAATCTACTATATACTAGGTGTATGTCATTATTTCATTGT AAAGTTTGATATTAAACATCACTCTTTCATGATGCTTGAGAGGTTACTCTGGGAAGAGGC CATGACATTTTTTGTCACTATGGCTTTGTCATTTTACAGAGTGAATGACAACAATAGTTT GTTGAATAAATGTGTTGATATGAGATCTACTTCATAAAAATGCACATGAATGCATGATGG AAATTAGAATAAATCATATTGAAAATTATGACTGTGACTCTTCTCTTCCAGTTTATCTAT ATTTTTTGCTTCAGAATAATTCTTAGTTTTCTAAAGTGTCATAGAAATTACAAAGGGTCT AGTCCAAAATGCTTATCTCATATCTATTATTTAAAAACAGGAGCCCTTGAAGCTATGTAT TTTCAATTACTTTATAATTACATACATTGCATGATTGAAATCAAATTGAGAAACATGTTT CTCTTGTGCATACAAAAAGTCTTATCATTGCCAACGTGCAGCCACTTCTGACAATTAAAG TTCTTTACATCAAGAACTGTTTTTTCATTTTCAGTCAAAGATACCAAGCATTAATTCAAG TGTTTTTCTTATTTTTTATTACATTCATGGACGTGTTGAGATGGAAGTTAGAAACCGAGG TAAAGAATAACTCTCATCTGAGATACAGGAAGAAAACTCAGGTATGCAGGAAAATATTAA TATAGTGCTTTAGGCCAAAGAGAGCACATCACCCTCACACGCAGCTTTAGCTTTTGGGGA TTTGATATGGTTTGGCTCTGTGTCCCCATCAAATTTCATCTTGAATTGTAAGCTCCATAA TCCTTACCTGTTGTGGACAGGACCTGGTGGGAGGTGATTGGATCATGGGGACAGTTTCCT CCATGCTGTTCTCATGATAGTGGGTGAGTTCTCATGAGATCTGATGGTTTTATAAGTGTT TGACAGTTCCTCCTATGCGCTCTCTCTTTTTTTCTCTCTCTCTCATTCTCGCTCTCTTGC CTGCTGCCATGTAAGACATGACTGCTTCCCCTTCTGCTGTGATTGTAAGTTTCCTGAGGC CTCTGCATCCATGCTCATGGAACTGTGAGTCAATTAAACTTCTTTTTGTTATAAATTACC AGTCTCTGACAGTTCTTTATAGCAGTGTGTAAACGGACTAATATAGGATTGATATAAATA CAAATAAAAGTACCCATTTGCAATACAGCCTCTGCCAATCCTGTGATTCTGACAACTCTC AGAGACAACCCTGATTCAGGTAAGCAGGCTTACACCAACTACATGTATATTACAAAATAT TTCCAATTCTGTCTCAATCTAAATATAAAAGTACAGCTATCTAAAGTCTACTTTGTATAT GTAATATATCTAACTTGAAAGTATGTGAAATTACACAAAAGCCTAGGAATGAACTTCAAT CTCTGTTCTTTTTCCTAAATTATTTATGCACACCATTTAAAATTCCAATAGGCTATCAAA CTGTTTGGCAATTTCAATAATAAAAATTATCTAGATTTTTAAAAAATTCAGATATTGCAA TATATCCATCCTTTTATACTGTTATTTTAAAATTCTTTTTTTGATAATAGTATTTTAAAA ATAATTAATTATAATAAACATTTAAACACAGTTTTCAATTATTTATTATATACCTGGTAA TGTGTTTTAAAATTTATGAAATTATCTAACTTAGTTCTTACAAACTCTTTGAAACAGTTA TTAGTATTGTTCAGTTTTACAGATGAGGACATCAGGCTCTGATTTATTACATTCCATTCT CACTTGAATCAATTCCATTCCAACACTTCAAAAAAACAAAATGAAACTATTATTGCCAGT GTTACAAATAAAATCCATTTTGAAAATCTAATATAAACTTTTACTTCCTGCCTGATCTTT CTACAGCATTGAATCTTCCTACTACCATTTACCTGGAAACTGTTCCTTTATTTCAGGGAC AACATAACCTTCCCTCTTCTCTCTCATGTCTTGCTTGCAGGTCCTTCTTACTTCATTCAG AAACTCATCGTCCAATCTCCAACCATGTAACTTTGAAATGTTCCACAGCTGAATTTGAGG CCACTGCGTTTATTATCAAGATTCACTCTCCTGGTTCCTAAATCCTGTCTCATGGCTTCA AATATCATTTAGATGCTGAGAATTAAAAAAAAATGCATCGCCAGTTATGGCCTCTATTTT AAAATCCAGAGTCAAGTTTAATTAACAATTTGACATTTTTCCTTGAACATATAGTACGGT AGACAATCTCAAATTAATATGCCACAATCGGAACTCAATCTAACCTTTTCATACTCTGAT CACCCCCTTCAGATGTGCTTTTATTCAAGGGTTCCATATTTTATAAAAATGAACATATAA AAATATTTGCAAATAGCCTCTATCCTATTAGCATTGTCAAAAATATTTGAATTTTCATCA ACTCCTCTATTTATCTTACACCATGTATTGAATCTAACAGGAAATTCAATTAGCACTATA TGTAGCCACAATAACTGGTTCTTGCCACCACCACCCTTTCTCTACTATATATTTTTCACA GTGACCTTTAGATTTTCTTGCTTCTGATTTGACAGCTCTAAGTTCAATCCAGGAGCCATT GTCAGTTTTTCAAAAGGAGGTGAGAATGTATGACTCTTCTGTTCTCTGGTTTCCCATCTC ACTCAGAAAACACATGCACCATTCTTTGTGCACCAAATAGCACAATCTTTAAAAGTAAAG GTTTATATTTTGCTTTATATATATTTTATCATCAATTTCCTTGAAATATATATTTCTAGT CAGTACAAACCACAGATTACTAGAGACTCTTCAGCAGAATAAGAAATAAGCTAAATATTA TGATAAATAAATAACACTCCAAAATAAGGAAAGGCTTCTGATGAATCTTGCCATTTTCAG GAAATCCACCTGGAATCCCATTCTCACAGTATTGGAACTCCCTAATTCTCCCTTTAGCTG CTCATTGTTCACCTAGTCTTTTCACTCTCTCCATCAAAAAAAAAATTTCCTCAGGAAAGG CTCTGATAGAGGAATCATAGTTAGATGAACTAAAACTTCAAATTCTACATATATATACAT ATATATACGTATATACACATATATACATATATACACATATATACATATATATACATATGT ATATATAACTTTAGCAGTAAAAACAAGTAGACTTTAATACTGTTACTTTATAATTCATTT AGGAAAAGAAGGAACACCTTTGCAACTACTCTCATTAAGTTACCAAGATTTTTTTCAATA CTAATCTTCACAATTCATATTCAAATACTAAGAATCACTAATGCCTTTAAAAAATACATG TGTATTTCCAATAATTTGATATAGGCTCTCAAAAAGTCATTACATTTTGAGGGTAAAATT GAAACAACCTAAACACTAATGCCGAGTAATGAATATAATAGTTCACACATATTAAACAGC TAATCCATATGTGTAAGACATTGTTATATATATACTTATACACAAAAACAAACATGTATG TGTGTGTATAAAATCTCAACAAATCTCCATAAGAATTATTAGAACTAGTAATTAGACACA GTTGTTCTACTTCTGTAACCCATGATCTTAAACCATTATAGAATAAACCTTAAAAGCAAT CATTATTTTCAAAGACAATTTTGAAACTTGCCTTGTGCAAGTTAGTAAATAACTGTGCTC CTTGGTTTCCTCATCTGTTACACGGGTAGAACCTACACTGTTACATGAAGATTAGAGCAG TTAATAGAATATTTTAGTATTTATAGATCTAGAATATAAAAAGGAATTAATAAGTTTTAA GGAGAAAAAAATAAGGGAAAAATAGTCTCATTTTCAACCCTACTAAACATAAAATGTTTT TTACATTTAATTTATACATGCAGGGTAGGTCAGTATACTAAAAATAAAGCACATTTAATT TGAAATTTTAGAAAGGGGTAGATTGTTCTTATTTAGAAAATTGCAGTACATTTTAATTTG TGAGCAGGAGGTCATGGTGTTATTTAGAAACAGTGACAAGAAACTTTTTTTGGCTATTGT AAATGGAAATGGAAAAAAAGAAAGAAAAGCCAAGAGTAGTCATTTGACTCCAACAAGCAG TTTTTAAAAACTATTTCATGTGATTATCAGCTTCAGTTTGAAAGGTTATATATCTGATAA ACAAAACACAAAGGAAAAGCTTGATAATTAACAAAAAACTCTATAGTATTTCCTTTTTTT CCATCTTTTCCCAGGTCAGATTCTTGCAAGCAATGGAAAATTAGTGTTTATTTAAGATTT AATGACAATGTTAATGCCACTGTCAATCTGGATTCTTTATCTAGAAAGGCAAATCTGATT TACATTAACCTGAACACCTTAATATCTAATTAAAATCTCAGCCTTATGGCTAAGTTCTTA GACATTTATTCTGTTTAACTCAGCAACAAAATATTATTAGTCACTTTCTTTTGAGAAAGG TGAGTCTAGTTTATCGGTACTATTAGGGCATTTTATAATCTGCAACCTAATTAGCCTTAA CAAAATATTTTGTACTCAGCATGACTCAAATATTTTACCCAATAACTTACTGAAAAATAA TTCTGCCATTGCATTTCCACTCTAATATACTGCAGTGATTTTCTGTTTGCACATATTTGT CCATGTCATATGTTTGCTTGAAAGAATGTAAAACAAAGAATGCATATAGATTATTAAAGA AATCCTCCCAAATTTGTTCACATATATTAGATCCTAAAACTAAATAGGTTAGTTTTTTTC TGAATTGAAATAGATTAACAGAACATATTAACTGAAATAACTGTCATATTATTTATAATT CTTATCAGACACATGCAATTGAGCCTATGACCGAGCATGAAGACTCTATAAAGGACATCG CTCAAGTACACAATATGATTTTCTTTAATTTTGATCTGAAAGACTGTTAATAGAAAGACT GAAATTCTGTCAAACAAATTGATTACATTTCTACTGGATTTGGGAAATATGTAGCATCTG TGATAAAGTACTTAATCATCACTTATTGTCTTTAGTGTGCAATTTATTATATCCATATTT TTATACCCCTCAAAGTATTTGCAAAATTAATAGAACTTTCTTAAGAATACAGTGACTGTC CTCAAAATCCACTTAATAAATTGGTAGCCTCGAATTTATATTTCATCTACTCTTCCAAAA TAATTATTGTATTGTTGGTTTTAAATCTAACATCTCACTATTTCTTTTCTATTTTATCAT ATGCTTTTCTGGTGCATATTTTTTTCTGCTTTATGTTGATTTTTATGATCCTATTTTTTT CTTTATTAAGTTTTAGGTGTAACTTTTTATTTTGGTAGTTACTTCATAGTTCATAATATG CAGCTTTAACTTACCACAGTCTACCTTCAAATGATATTACATCACTCAGACTGATTTGTG AGTACAGAGAGACTGGGCAGGGACGTAGATGATGAATCAGAAGCACCTGACTCATTTAAA ATGCTCACTAATCTTAGTAAAATAAACCCATACAGAAAATTCTTTTATTTTAAGGTGAGT AAACATGCACACACATGGCCCTGCAAGGTCATTCTGTCAATCAGCCTTAATCCAACCCAT GAGATATCAGTTTACCAGTTTATGATCATTGCCATAGAAGAGTTTTTTTATTTTAGATTC TAAGTTTAAACTGAAGATTCAATGGATGTGGAACTAGTTTTATTTTTGAGCGAGAAAATA ACTCAATTAAATGTACTGTGTCTCAAAATATGCAGTATACACACCACCATGAAAACGAGA CAACAGTAAATAAATTATGACATCTAGAAAATTAGGTAAGACTGTGTTCAATAATGAGGC AAAACAGGATGTGAATGTCACTTACGCTATCAGAGAGAAATGTGGGGTTTCATCCACTAA ATGTGAGGTTGAATGTATAGAACGTTATTTCAAATATGTCTTGATTTGTATCTAAATTTA TATCCTATAAAATCATGCAGAATATGAGGAGTCATTATCTAATTTTCAGTAGGAAAAATG TGAATCAGTACTAATACTAAAAACTAATAATTTACTCAATGCCAGGCAATGTTTCTTGTG TTTTATGTTTTTAGAAAACAATTATGAGATAATTGTGAAGAAAACAATTCTTCACTTTTC AAGAAAGAAAACCAAAATAATGAGAAACTAAGTAAGTGGCCCACCCAACGTCGTATAGTT AAGAAATGACTAAGTTGTAGACCTTGTAGACCTTAACATGGTTTGTTTGTTTGTTTGTTT GTTTGTTTGTTTTGAGATGGCATCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCAGGA TCTCGGCTCACTGCAAGCTCTGCCTCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCC AAGTAGCTGGGACTACAGGTGTCCACCACCACTCTCAGGTAATTTTTTTGTGTTTTTAGT AGAGACAGGGTTTCACCATATTATCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGC CTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGACGTGAGCCACCACGCCCGGCCGACCT TAGCATGTTTTTAAGTAAAATGTATTATTTTTCATGTGTAATATTTGCTCTGTCTCTCAT GTATACATAAAATTATAAATATAATCATGAAGAGAATTATAATAGCCAACTTTCTCTATA TTTCAGAGATATTGGTTTGGCATTGCTTTCGGCAGATATTTCAACATTAGCCTCTGGAGT GGAGTTGGGGACAGGTTGATCTCAGTGTTTCAAAAATATATGAGAACTGTGAACCTATAT TAGTGGATTGCCTATTGGCGACTTCTAGTTGAACACTATCAAAATTGACAACTAAAAAAA TAATGAAATGAGAGAAAGTGTTTATAGCGCTTAAGAGGATAAATTAGTTTCTTTATGTCT AGATTTTATATTAAATAAAGAGCTTTCAGGAAAAGTAAATGACAGTTAATGATTTTGATT ATAATCAGTCAGATTTTTTTCCATATTTGAGCAAAAATTGTAATTGACTTATCCACTGCT TTCAGTGTAGATTAGCTGAATCATCTAACTTATGTCATCTCTTATAAATATTGATTGAGA TGAAAAATGAATAAATGATTTATTTATCTTATAACAGTTCTATGTTGATAATGTAAAAAA TACTGACAGGTTCATCTAAAATATGTTTGGATAAGCTACATTATATATGATTCATATCTT ATGTATAATTTATATATCATATTTGATTGGTTCATACACAAAGGAACAAATGTTTCTATA TAAGAAAGTTATTTTGCTTATTATAGAATTTAAAACTAAAATGATTCTTCCACGATGGCC ATTTAGCAATTTAAATTTAGGAAACTTCTGGCATGTTCAATTGAGTATTTACTTTGCATA ATTGTGTTCCATATCTTAATGCATTCCCTTTAGCAGTTTCTTTCAGCAAGCAACACATGT AACCTTGTTTCTCACTAAATATTTTTTATTTTAGCAAAGTTTTAGACCTAGAGATTTAAA GAAAAATTGCCAAGATGTTACAAACATGAACTCTTGAACCGAATCTTTTATTTTTAAGCA TGCAAAACGGTGTGGTTTTTTAAAACCCTGAAGACATAAATGTACCACTGAGAACCCAAA GAAAATTGGACTGTTTTGTTTTGTGATTTGATGTCTGAAAAATAAAATCCTTTAGTTTCC TTTCATTTTTCCTCAGAGAATATAGACTGTGTTGTGATGTCAAACTCATTCTGAGTTTAG ATGCCCCATGGGCAAATCGTTTGGTCTAATTAAAACAAAATGAAGACAAATCTCTTACAA GTAAATCTTTGATGGTGGGAAATGTAGCGTCATGTTTTAAAAGCCTTCACAGAAGACAAA GTACCTCTCAATCTTGTAACTCTACTTTTTATAGCTACCCAAAATAATTATTAAGGCATA TTTGATATATTGTAATCAATTTATATTTGTGTTTTGTTTAATAATTGGGCTCCTTTGGAC CATTTGCTGCAAATATCCTATATTAAAAAAAACTTTGTCTAAATATATCATGCAGAAAAA TATTTATACCTAAAAATATAAACTCCATTAACAAAAATTGTTCAGCAAAACTCTATTAAT TCAATACATTGTATGGTTAATTTTTGTAGCCAATTTTTCCTTTTCTTCTCTCTAATGATG TGATGTTCTTCAATGTCTTCTGAAAACTTGAGCATAGGAAGTTGGAAGTGTATAAAGCAA AACAAATAGTAAGGAGAGAATTTAGAATGCTAATTTTTGAAGGGGAAATATAAATTTTAC AACTCTTAGTTTGCATTTTAAATTTATATTATTATCTGTATTTAAGTATTTAAGTTGATT TTCACCAGCGTGTTAGTGTGTTTGTGTTGTTGTAAAACAAATACCTAAGACTGGGTCATT TATAAAGAAAATAGATTTATTTGGCCCTTGGTTCTGCAGATTGTACACAATGCATAGTGT CAGCATCTGCTTGTGGTGAGGGCCTCAGGAAGATTACAATCATGGCAGAATTTGAAGGGG AGCCAGCATGTCATAGGGCACGAGAGGGAGCAAGAGAGAGAGGGAAGGTGCCACACTCTT TTAAACAACTAGATCTCCTGTAAACTCTTTACCACTCATTACCCAGGGGAGGGAACCAAA CCATTCATGAGGGATTTGCCCCCATGACCTAATACCTCCCACTAGGCCCCATATCCGACA ATACAGGTCACATTTTAATATGAGACTTGGAGGGGATAAAACATCCAAACCATATCAACT GTTCACTGCTAACTACTAAATCAAAGAATTAATTTTTTACAGGCAATGTATTATTCTTCA TTCAAAGAAAAATACTTGACTGGACCTTATGAGGAGAAAATGTTAATCTCTTGCAGTTTT TAATTAAATAAAATAGTTTGAGGCTATTTGTGCAAATTAAGGCCATTGAGAAGGACTGTA GACTATAAAAAGATTCCAGACATTTTCTATAAACATATTTCATTTTATATATATATATAT ATATATATATATATATATATATATATATATATATATAGTTGTTATCATGGTAGATTTATA CCACTGCCATCTGGAAGTAATTCCCTTATTCAATACAGAAGGATTTCTCATCCTTCTCCT AAATATTTTCTTCTAGCTCAGAGTGCCTGTGGCCAAAACAAGGGATTTTAAAACAAAAAC AAAAAATTCTGCTATCCCCATGTGGGTTATCTTTCTTTTGTAGTCTTCTTTTTACTTGAG TTAAAATATTTCCTTTGAATTTCGACTGGCAAAGATACTGAAGGACATCGAATGTGGTTT AGGGCACTGTTCCTGCGCCTGTGTTCACTAGATCAGTAGTGGAGGTGACTGGAGATATTG GAAGAAAGAAAGAAACTAGGGTAGCTCATATCACCCATTCCACGTTTTTTCTCTTTAGGA TGTCCCAGCCTGCAGTGAAAATGAATTCTGTTCTGCCTCTGCTGTGCGGTAAATTTAGCG ATAAAGTTTCTGCTCTGTGCTCTGTACTGGAGTGTAGTGTAGGAAAATCCCTGTTGCTAA GCACCACGCCAACAACACCATGAGCTACAGAGATCACATGTTTATTTCATTATGCTTTAC TTCTGTTTTTTGTTTTGTTTTTTTTTTTTTTTGAGACGGAGGAGTCTGGCTCTGTAGCCC AGGCTGGAGTGCCGTGGCGCGATCTCGGCTCACTGCAAGCTCTGCCTCCCGGGTTCACGC CATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCACGCCCAG CTAATTTTTTATATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGAATGGTCTTGA TCTCCTGAGCTCATGATCTGCCCACCTCGGCCTCCCAAAGTTCATTATGCTTTACTTCCA TGTCTATCTCGAATTGTTCCATATTCAGAGAAAACAGGAAGGTAAGTTGTTAACATTCTT CATTGCAACCAATTTTTTAGAACTAATTCTACATTGAGGAATGTCTTATATTTTAACCAA AACCTTTCGATAAATTACAGAGTTGCTGAATATATCTAGATCTAAATCTTAAACTATATC TATAGCTATTATATAGATGTATATGATTTATCAAGAGCTATTATCTGGAATATATACTGG ATTCCTTTTACAATTTTCATAATGTAACCAGAAAATGACCCTTGAGATCCTTGAGAGTGA TTATGTAAACATATCCTTGATTTGGTGTCTCCAGCCTAATTATCACAGTTAAAATTTTGG TATTAAAAATGGAGCAAAGATAATAAGACTTGTAAAGCAGCAGACCTTACAAAATGTTAA AAACAATTTTATTTACGTAGTGCCTCCACACAGACCTAATTATATGTATTAAACCTAATG TTTAACATTATTAGCGAGTCAGAGAATTTAGAAAAATCAGACATAATTTTAGATAAAATA AATATTAATACTAGTCATTAATATTAATCCCTGTTTGATAAAATGACTCTATATGAAAAT AACTGCCCTCAAATTACTTTCATCTCACATATTTTTAATGAAAGGAAATGGTGGCTGGGG GCAGTGGCTCACACCTGTAATAACAACACTTTGGGAGGCCAAGGCCGCAGATCACTTGAG ATCAGGAGTTCAAGACCAACCTGGCCAACCAGGTGAAACTCCATCTTTACTAAAAATACA AAAGTTAGCTGGTTGTGGTGGTGGGTGTAATCCTAGCTACTCGGGAGGCTAAGGCAGGAG AATCACTTGAACACAGGAGGTGGAGGGTGCAGTGAGCCAAGATCGTGCTACTGCACTTCA ACCTTTGCAAGAGATCAAAACTCTGTCTCAATAAATAAATAAATAAATAAATAAATAAAT AAGGAGATGGTATGGAATCATTATTAATGTTGGGCCCCTCATGTTAGCTAATATGTTTAA ACCTAGGTCAAGATAGAAACTGACCCAGATTATTAGCATGTTTCAGTGCATAATATTTTA AAATAATTCAACACTGACACATAATACTATGCTATTCCACTTAGATATAAAAAAATGGCA AGAGAAGTCTCATGTTCTTGTCCCGGCATGGTGACTTACACCTGTAATCCTAGCACTTTG GGAAGCCAAGTGGGGAGGATCCCTTGAGGCCAGAAGTTTGAAACCAGACTGGGCAACATA GTGAGACCTATCTCTACAGAAAATTTAAAAACTAGATGGGCGTTGTGGCAAGCACCTGTA GTCCCAGCTACTGGGGAGGCTGAGGTGGGAGAATTGCTTTTCCCAGGAGTTCCAGGCTAC AGGGAGCTATGATCACATCACTGCACCCCAGCCTCCGTAATACAGTGAGACCCTGTCTCT TAAACAAAAACAAAAAATAATCCCAGAATTCTAATGTTCTTATATGATACAGGACTTTTA AAAATTAGCCAGGCATGGTGGCCCATGCCTGTAGTCCCGGCTACTTGGAAGGCTGAGGCA CGAGAATCACTTGAGCCTGGGAGGCGGAGGTGGCAGTGAGTCGAGATCACGCCACTATAC TCCAGCCTGGATGGTAGAGTGAAACTCTGTCTCAAAATAAATAAATGAGTGAAAGTACAC CGAAAGTTTTAACTTAACAAATTTTATTTACGCCTCACATTGATGGAGTGACAAGAACAA ATAAGTAATACTAATGAAGGTATAGGATATTTTACAATTTTTTAAAAATTAGACCCTTAT ATACACAAAGTAATTGAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTC TCGCTCTGTCACCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTTGCTGCAACCTTCGCCT CCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCTCGAGTAGCTGGGACTACAGGCACGCG CCACCACGCCCGGCTAATTTTTTGTATATTTAGTAGAGACGGGGTTTCACCATGTTGGCC ACGATGGTTTCCATCTCTTGACCTCGTGATCCACCTGCCTGGGCCTCCCAATGTGCTGGG ATTACAGGTGTGAACCACCACGCTCAGCTGCAAAGTGATTTAAATTTATCAACAATTTTA ATGCAAAATTTTTGTCATTTGTGATATTTTCCAATAGCTTATCCGAATTCCTTAGAATCA GATTTCAAAATAAGATTCCCAAGTCAGATTTCTTTGAAATTACAATCCGAAAATATTTAG ATTTTAGAAAGGTAATGTGGTAAATATTCTGCCTATTATGGAATAACTCTAATGGCAAAT CATATGAATAATCACATGAACTGGGATCAATAAGACTATAAATACCCCTGGTCGGGTGCG GTGGCTCACACCTGTAATCCTAGCACTTGGTGAGGTTGAGGCGGGTGGATCACAAGGTCA GGAAGTCGAGACCATCCTGGCTAACACGGTGAAATTCCGTCTCTACTAAAAATACAAAAA ATTAGCTGGGCGTGGTGGCAGGCACATGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGA GAATGAATGGCGTGAACCCAGGAAGTGCAGCTTGCAGTGAGCCAAGATCAAGCCACTGCA CTCCAGCCTGGGCGACAGAGCGAGACTCCGTCAATTCACTAGGGATAAAAGTCAGAAGAA CAGAAATTGTGAGTTCCTTTGTGAAGATCCAAGGACCTTCAAGGACCTCTGAATAGCCAA GAATAATCATTCCTGTTTTTCATCTTCAATGGATAAAAGAGCCCATTATACCTTTCTAGC CTATTCTGGAATAAGTAACAATGAAATTTTATTTAGTGTAAACTAACAAAGAAAACAGAG TAAGTTAATGAAATGTAGTCTCTACAACTTGTTAGACTGTTTATTTTTTATTTGTTTTTT ATTTTTAGTTGGACTTTGTTTTTGAGACGGAATCTCGCTCTGTCACCCAGTCTGGAGGGC AAGGGCTTGATCTCGGCTCACTGCAACCTCTGCTTCTCAGGTTCTAGTGATGCTCCCTGC CTCAGTCTCCCTAGTAGCTGGGATTACAGGCGCACACCACCACGCCCAGCTATTTTTAGT AAAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCCAACTCCTGACCTCAGGTGATCT GCCCGCTTCAACCTCCCAAAGTGCTGGGATTACAGGCTTGAGTCACGGCACCAGGCAACA TGCTAATTTTTGTATGTGTGGTAGAGACGGGGTTTCACTCCATGTTGGCCAGGCAGGTCT CCACCTCGATCTCAGGTGATCCACCGGACTCGGCCTCCCAAAATACTGGGATTACAGGCC AGAGTCACCGCGACCGGCCTGCGTCCATGTTACTTAAAGTACAAAGTAACCTACAAAGTA ACCCGCCAGGCGCGGTGGCTCACGCCTGAAATCCCAGCATTTTCAGAGGCCGAGGCAGGC GAATCACCTGAGGTCGGGAGTTGCCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCT CTACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTAGCCAGCATGGTGGCACATAC CTGTAATCCCGGCTACTCAAGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGA GGTTGTTGCAGTGAGCCGAGATCGCACCATTGCACTGTAGCCTGGGCGTCAAGAGCCAAA CTCCGTCTCAAGAAAAAAAGATTACATCCTGGCACGGTGGTTCATGCCTGTAGTGGCAGC AGCGGTGGCAACCCCAGAACCTGTCCGTGCCACCAGCAGCGGGGAACCCCAGGGTCGGAC GCCGCCACTGCGCCTAAATCAGGCGGTGGGACCTCAGCTGTGTGAGGGCGGGAACCTGCC GCAAAGCCTCATCCTGGCAACTATACATGGCCCAGAGGTCGCGAGCCTGCGCTGCCAGCG CGGGCCAAGGAAGAGCAGAGCCCAGGGTGGAAGGGCGGTGCACTCGGCGACCCTCAGCGG TCTGGGCCCAGCCCTGCAGCCTCCACCGTGGACTCAGGTGCAGCTCCCACCTGAACATGG CACGCGGCAGCGGGGGCTCCAACCCGGACCCTGTCCGTGCCAGCAGCAGGGCGGATACTT GGGCCAGAAGCTTCCAGGGCGCCTAAGTGAGGGGGTCGGTCCCCAGCTGCAGGAGGGCGG GAATCGACGCTCAGCGCGGCCCTGGAGGCTGCACGGTGCCCAGTACCAGGGTCCAGCTCC TGGATCGCGGGTCGAGGAGGGGCCAGGGGCGGCTATGTCAAGCAGGCCGTGTTGCAGGGA GCCCCACACGTTCCGCTCCAGGGAGGCCCGCCAGCCCGGCAGCGCCTCAGCGGCCGGTGC CACCTGCACGCGGTGCCCGGTGGAGCGCGGCCAGGGCGCGTGTCTCCTCAGCCTGCTGAG CTGCGCGTGAGCTGCTGCTGTAACGCTCTAACGTTAGAGCAGCTAACGGCTCTGCTCAGA ATTTCTCCCGACAGAGGCCGGAGTGTTCAAGAGCTTGGCGATACAGAAATTTCTGCTGGT GTTGGGGCGGGTGCGGGAACTGAAGACGGGCGAGTGCGAGCCGGGGGCGGGTGCTGGGGA AGGGTAAGCGGGAAGCGAGGGCGAGGGGTAGGGGCTGGGGAAGGGCGAGCGGGAGGCGCG GGCTCTCTCTAGCAGGGGGCTGCAGCCATGAAGAGGCTCTTAGCTGCCGCTGGCAAGGGC GTGCGGGGCCCGGAGCCCCCGAACCCCTTCAGCGAACGGGTCTACACTGAGAAGGACTAC GGGACCATCTACTTCGGGGATCTAGGGAAGATCCATACAGCTGCCTCCCGGGGCCAAGTC CAGAAGCTGGAGAAGATGACAGTAGGGAAGAAGCCCGTCAACCTGAACAAAAGAGATATG AAGAAGAGGTACCAGGCCCTGCCTGAGCCGGGGCTGCAGGAGGAGGAGGCGGCTGTGGGA GGATCGCCCCTTCAGAGTGGTGGCTGGGGGTCCTGGGGACGAGGGGAGCAGGTGGAGGAG TGGCGGGCGATGGGGCGGCCGTCCTGGGCCCCGAGGTCTTGGCCTTCTTCCCGGTCAGGC CCCCCAGGCCTGGGATGGGGGCGCCCTGCAGGGCAGAGGGCACAGGCCACCTTAAAATCA ACCCCAAGCTTTAGCTGCTTTCTCCTTCACTCCCACTTCCCCTCACAAAGCACTCTGTAG AAAATTTTAAAGTGATTAAACTCACAAAATTAAGTACATACAGGGTTTTACTTTTAATGT ACAGGTTTTAAAAGATAATGTTAGATACACTATGAAATGGTGCATAATGAACTAATTCCC ATAATATATGACCTTCTTGGCTAAAAATTCTTTGGATAAAGTCCAATGTCCATTTTGATA TCAATGAATGTCTATGTAAATATGTTCTTTGCTGAGGGACCTTAGAAGGAAACTTCGAGG TGGGAAGATAGTTTATGTTCTTGAATTTAAGAAGACTCATTTTTCTCAAGATGCGACTTA CCAGTTTTACATAAACCAAATAAAGCTATTAACGTTTTAACATTTTTTAAATTACACAGG CTTTTACTGTTGTGATGACATTTTAAATATTTTGTAATGGAGTAGAAAAGTCTTGCCCTT CTAGATATCAAAATGCGCTATTAATTTGCACAAAATGGGCCAGGAGCGGTGGCTCACGCC TGTAATCCCAGCACTTTGGGCGGCCGAGGCGGGTGGATCATCTGAGGTCAGGAGTTCAAG ACCAGCCTGGCCAATATGGTGAAACACCGTCTCTACAAAAATACAAAAATTAGCTGGGCC TGATGTCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGGGAGAATTGCTTCAA CCTGGTAGGTGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCAATCCAGCCTAGGTGAC AGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCACAGATTG TTTGCTAACAGCTGAAAAGACAGGTAAATGAATACAACAGAATAGAAAATCCAGAAACAC CCAAACATATGTAAGAATTTAGAACTTGATAATGATCACAAGGATCATTATCCTTGTGGA AAAGAATTAGTTTCATAATTCTTTTAGGAATATGAATTATTAGGAAAAGAATTAGTTTCA TAAGTGAAATGCCTGCTTTTTGGAGAAAACTAGATTTTTATGGCACAAAATAAGTTCCTG ATGGAATATAGATTAAAAATTTTTAATATACAAAAAGATAAAAATACCAGAAAAAACATA AATGCCTATTTACACAGATACATTTTTATGTTGACAAAACCTTTCTAAGAAGCTCAGAAG CAAGCATTCTGAAGAGTAATTTAGTAAAACAAAAATTAAATCACCCTGCATATGAGAAAA AATAAAAGGCAGCATACTTGTAAAATATTTACTACTCATGTATGTGTGTGTGTGTATACA TATTAGAATTAAAAATCTTCCTTTTATAGAGAATTCACTCAAATCAACAGAAAACCCTCT AATTTAAAATTGGGCAATTTAAGTTAGAGATCTAAATTGCAGATCTAAAAAAGTACTTGG CCTCTAATTTAAAACTGGGCAAAGTCCTTTTTTAAGATCTGCAAGTAACCTATGCACACA GGAAACAATATTAGTGTTCCTGGTTAGAGAAGGCATTTAAGTTAAAAGAGGAATCAAATA CTGTTTTCTATCCACAAAGTTTGTGAGGATAAAAAGCAGTGATATTTATAGTACTCCTTA AAGTGTAAGTTGCAGATGAGTTTTCAAATAAACAATTTGATGGTAAGTACCATATTTAAA AAATTGTATATGCCCATTAGTGATCCATTCTATTATACTAAAATATTTTTAGAAAATAAT GCAACATACACACAATTTCTTTTCTGAGCACTGCTTAAAATATCAATGTATTAAAAAGAA TCCATTTAATGGCTTTTATAAATACATTTCAGTGAGTTTACAGCATGGGATAATATGTGA CCACTCAAGGTAGAAACATATACGGAAGTATGTTGACATTTGAAAATGTATTTTGGTGTA CCAAGTGAGGGTAAAATTCAGTTTGATTATACATACAGACTATGGTCTTGTGTTATCTGA AATTATGTCCAAAATTTGATAACATTTGCTATTTGAGGATACTTGTTTTAATATAAAATG TTTTTCCTTTTTTTATCTTTGATTTCTGCATTGAGCATGTACGATGCTATTAGTAAAAGT TTATTATTAATGAAATAATTTTTGGGAGGAGCAGCAATATGTATTTTGCACAGATGAAAA TAATTTCTCACTTTCTATATTTTATTTTTTTGTGCATTTGTATATTCTGTGAACTTTTAG CATCTTCAGAAGAGAATATTTTTATCTCTGCTTATTGATTTACATATACATTTTATTAAA CACATTTTTATTATATATAGGCTTATTACATATATGTCAATAACTATAGATTAATCATTT TAGTGTAGTTTTATTATTAGAAAAATAAAATGACAAATATAAGTGTTTTATTTATAGCAG TTTTTTAAGATACTGTACTTCCCAACTGTATTTATCCATTCTTTTAATCCATTTATCACA TGTAAGCTGGATGCCTATTATGTAGAAGATACATTCTATTAACTCTCAAGACCTTTTCAT CCTTAAAAATTTCATGTTTACCTGCTCAGCCTGAGCAAAGTGAGAGATTTAAAATTGGAG TATTAGGACTGAATCTCAATTAAGCTTTTCCTCTCATGTTTCAAACAAAAACACTTCTGA AGTGAGAAACGAGTAAAAGATAACTACCAACCAGGTTTTGGAAATTTATAACAGCTCTAA ATAGTAATATTAATCATCAAAAATACCTAATTTACATGCATTCTATAAATCTAAATATGA ATTTCCATACATTCTGTAAATCTAAATAGGGAATAAAATGAGCCATACCTATTTATTTGA AACCAAAGTTTTCTTTGGCTTGAAGTTTTTAAAATCTTGAGGAAGTAGTTTGTTTTAACA ATTTGTTGTTTTTATTTCAACTCTCCTATTGTGTAGTCCTCTAAAAAGCTAAAATTTCTT TCAGTGTTAATCCTGTGACTAGGACTGCCATCGTCCTGTTGTATATACCGTATTCCACTT CTTGGAAGACACTGTGAATTGTGTGATGCCTCTTTATTTTATGCACCAATTAAAGATTGT TTAAATTTCTGCCAAATATAGTTGTAATAAATAATGAATTATAAATGGCATTTCAATGTC AGAGATGTTAAAATATGAGCAATTGAGCATCTTAGAATCATTAAAATACTGTGTTATCTC TAACCTTTAAAACACACCACGAAGTAGGCATAATTGCACCATTTTACTTAAAATGTTTTC TTTATTAAGTAGTAGTAATAATTATAATATCTAACAATTACTTAGCTGTTACATGTACTA GGAACTCTCCAAAATACTTTGCATAGATTCTCAATGAGGCATCACAGTGATGTCCTGTGA GATAACGGCTGTATTCATCTCCATTTTATTGATGAGAAAAGCGAGGTGCAGAAAGTTTAA GTGACAGCTAGAAAGTGAAAGACCTTAAAGTAATATTCAAGCTCAAGTTGAACTGAATCC AAAGGCCAAGCTCTTTGTATTCAAACAGGCCACTCTTTCATTAATGCGGTGAGTAATAAG AGAACGAATGTTGTACTTTCTTCAGGAGAATATTAAATATTTGTTTTGAAGGTAGAGAAA GAGCATGGTATTTAATGTTTACAATTACCTAAATCGTTGTATGTTTTGAGACAGTGGGCT ATACTTTGCCTAAAAGTCCTCTCACTCTCGTAGGACTGCTCTACACTGGGCCTGTGTCAA TGGCCATGCAGAAGTAGTAACATTTCTGGTAGACAGAAAGTGCCAGCTTAATGTCCTTGA TGGCGAAGGGAGGACACCTCTGATGAAGGTAAATAGTAGCCAGTTTTTTCAGCGGGAGAT GGATTTGGTTTAAATACATAGAATAAAAATGAATTTAGTTGAAATACAACTAGTTTGTGA AACCTGTGGAATACTTATTTTGATTTCCTATAATTTATAATGTACTTCTTGCTTTAATAC TGACAGGCTCTACAATGCGAGAGGGAGGCTTGTGCAAATATTCTCATAGATGCTGGTGCT GATCTAAATTATGTAGATGTGTATGGCAACACGGCTCTCCATTATGCCGTTTATAGTGAG AATTTGTTAATGGTGGCAACACTGCTGTCCTATGGTGCAGTCATCGAGGTGCAAAACAAG GTAGACATTAACCAATGTTATTTTCAAAATATTTGAAATCCATTTGTTTTAATGTTAACA TATGTAAGGCTTTTATATTTGGAAACACAAACATTCCTTGAGTGAAAATAATTTGAAAGA ACTTAATTATCTAAGATTTAACCTTAAATATTAATTTTTTAAAAGAACTATTAGAGAGTA TGGCTTTTCTGTGCATTTATGATAAATATTTGAATTTGTTAAAGGTAAAACTTTTTCAAA TATTCTTTCCTACCCAAGGTTTTTTTTTCTTTCCAATTAGTGTAAAACTACAGGAAAGCA AAATTTGCCTGTGTAAATTGAGTCAACATGTAAAATTTAGGATACGTGCAGAAATCTGGA TTTCCTCTTAAAGGATTGCATCTGGTGTCTCTTGAGCACATATGACTGTTTGGTATGCTA AGAGAACGTTCTAGCTTTACACAAAGCATGTTTCCAGTTTGCCACTGTGCCCACCTAGTT ACATCACTTACTGAACTTACCTCTTTTGCCTCTGTAAATATTTCAGTTATCAATTCCTCT CTCATAGTATATTTTGGTAAAGGTTTCAAGGTATTCAAGACAGTTGATAGCTGTTTATAA TATATAGTTTATATTTTACATTAATTCATTAATACTGGGGTTGACTTCTAGAATTTCGAA GACTTTTTAAACAATGATTTTTCTGTATATAAACCATAAATAATAATCTTTTATTAGAAT GCCTTTAAGCCTTTTTAGATTAATTTTGGTTGTATTTGAATAGGTTATGCATATTGCAGA AAATATTATATCCTTCTTCTTAGAATTGTCCCTTAAAATTCAAGTGATTTAGGGGCTTCT GTTATGCTAATCCACATAGATGAGTTAGAACTTTCATTAGTAAGCCATTTTATTCATATT TTTGATATTTTTCCAAAAATTAAGTAGCAATTACAATAGCAACCAGAATAAAAATGGATT ATTGCATTTAAAGAAGTAGATATGCATTAGGATCCTAGGATTATCATTATAATTGAGAAT AAACTTTTATACTGAATTTCTAATAGCCGAGAAAAAATTCTATTGTCTTGTAATAGGAGA AACCTCATGGACCATTTAATAATAAGCAGTCAAAGTTCATTTGAAGCCAATCTCTTTTGA TTTAGAGCCACTTCCTTAGTGACCCATTTAGAGCAGGAGTGCCTGACATTGGCATCTGGG ATCTTGGGATTATTGATAGAATAGAATCAAGAGAGTTTGTATCACCTACAGGAAACCTCC ATTTTTCTTGGGAAGCTTTCAAAACTGTATGCCTGAAATTCTAATTTGTCAAATGTTAAT CTCTGCCACAAAAATATATTGTCAAGTAAGTATTAGGCAAAGTTCAAGTCATTTATTGAA TAATGGACATTTAGTTCACAGTTTTATAATATTTCTTGAACATAGATAATGGTGGAATCT GTTGGGGTACAGTGCTTCTGGTAAGGTAATTATTCTTTGGAATATAGTTTAAGAAACACT GCTCTAGAGGTAATATTATAGATTACTCATTTAGTCAAAAACAAAGTATTTACTACTATG TCTTAGGGTTTAAGGATATAGAGATAAAAGATACAGCCCTTGCCCTCATGAAGCTCTTGG TTTAGATGGGAAACCATAAAATCATTACAATATAATGATTTTTGGAGATAACCAGAATTA ATGTGGTGATGCAGAGGCTGAATATTTACAAGGGAAGGTGCAGTGCATGGGAAAGCACAG AAAAAGGAGAAAGAAGGGACTGCTATTGATTTACTTATTTACTTTCTACTTTATGTGTTT AAGTTAATAGGATATAATATAAGGTATTCAGTTCAGCTGAGAAATATGTAATTTCATGAA TTATATATTGTTCTGCTATTTTACAGGCTAGCCTCACACCCCTTTTACTGGCCATACAGA AAAGAAGCAAGCAAACTGTGGAATTTTTACTAACAAAAAATGCAAATGCAAACGCATTTA ATGAGTCTAAATGGTATGGTAGTTCTTTTTTTTTACTAAAAAACACTTGACTAGTGTTCT AGAGTAATAATGCTCAAGTCAGAAATATTAAATTAACAACATTTAGTTAAAATTATTAGA TTATAGTGAAACATATCAACACAAATTATCAGAAGAAAAGCAATTATTTGGACTGGTCAA CATAAAAAACAGTGTATAGTAGGACTTATCTTCTCTTATTATATTGACTGATTCTTATTT GTAATCTGATGATTTTGGTTGCATTATTTTCTATTAGCTAAAGTGGTTCTGCATCAGTTT TAAGAAGTATGAACTTTTTTAGTTTGCTTTATAATTCAATATTGAATTATTAACAGTTTT ATAGTATTTTTCTAACTTCTCTTTTTTATACACTTTTTTAATTTCTTTTTTTATTATTAT TATACTTTTAAGTTTTAGGGTACATGTGCACATTGTGCAGGTTTGTTACATATGTATACG TGTGCCATGTTGGTGGGCTGCACCCATTAACTCGTCATTTAGCATTAGGTATATCTCCTA ATGCTATCCCTCCCCCTTCCTTCCCCTCACCCCTCAACAGTCCCTGGTGTGTGATGTTCC CCTTCCTGTGTCCATGTGTTCTCACTGTTCACTTCCCACCTATGAGTGAGAACATGTGGT GTTTGGTTTTTTGTCCTTGCGATAGTTTGCTGAGAATGATAGTTTCCAGCTTCATCCATG TTCCTACAAAGGACATGAACTCATCATTTTTTATGGCTGCATAGTATTCCATGGTGTATA TGTGCCACATTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGGTTGGTTCCAAGTCT TTGCTATTGTGAATAGTGCCACAATAAACATACGTGTGCATGTGTCTTTATAGCAGCATG ATTTAGAGTCCTTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAATGGTATTTCTA GTTCTAGATCCCTGAGGAATCGCCACACCGACTTCCACAATGGTTGAACTAGTTTACATT CCCACCAACAGTGTAAAAGTGTTCCTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTC CTGACTTTTTAATGATCGCCATTCTAACTAGTGTGAGATGGTATCTCATTGTGGTTTTGA TTTGCATTTCTCTGATGGCCAGTGATGGTGAGCATTTTTTCATGTGTCTTTTGGCTGCAT AAATGTCTTCTTTTGAGAAGTGTCTGTTCATACCCTTTGCCCACTTTTTGATGGGGTTGT TTGTTTTTTTCTTGTAAATTTGTTTGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGT TAGATGAGTAGGTTGCAAAAATTTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGG TAGTTTCTTTTGCTGTGCAGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCAATTTTGG CTTTTGTTGCCATTGCTTTTGGTGTTTTAGATGTGAAGTCCTTGCCCATGCCTATGTCCT GAATGGTATTGCCTAGGTTTTCTTCTAGAGTTTTTATGGTTTTAGGTCTAACATGTAAGT CTTTAATCCATCCTGAATTAATTTTTACACCTTATACACTTTTTAAAAAATGCAATATTT GCTGGGCATGGTAGTTGTTGCCTGTTATCCCAGCAGTTTGGGAGGCCAAGGTGGTTGGAT CACTTGAGGCCAGGAGTTTGAGACCAGCCTAGCCAATATGGTAAAACCGCATCTCTACTA AAAATACAAAAATTACTGCCATGGTGGCGCATGCCTGTAGTCCCAGCTACTCAGGGGACT GAGGCACGAGAATCGCTTGAACCCAGAAGGCAGAGGTTGCAGTGAGCTGAGATCATGCTA CCACACTCCAGCCTGGGTAATAGAGCGAGATTCTGTCTCAAAGGAAAAAAAAAGCAATAT TAAATAGAAACAGGAGTTTAAAACCATTTTGTCTTTAGGACGACTATTTGCTTTAATAAA GTTGTTTTCTTTGAAGCATATTAATTTTAGGTTATCCCTATGTGACTGACTATTAATTGC TATCACCAGATACTGTGAATTTATTATTTTTTTCATTTTTTTCATAGTGTATTTTTATTT TTAATTTGTATGGGTAGAGGGAAGAAAGACATCTTTAATTTGATTAATATTTTAGTTAAT TAAGATAAGCCATAGGTGAATGATAAAGAGAAAAGAGATAGGCTTTTGATTCACACAAGA CTGAGTTTAATTTCTAGCTTCCTCACTTGATAGGTGTGACCTTGCAAACATTACATAATA CCGAGTATGACTTTCTATGTGAAAAGGAGAATAATGATATGTGCTTTAAGGATGATTGTG TTGAAGTAACATTATAAATATCAACAGCATTTAATTCAGTGTCTCATACATTCTTATCAA CATCATTAACTAAACTTACTATGACTACTACTAATATCATTATTCCTAATATTGTTTTAA GCCTTCAGATTGCTCTCTCTTGTCTGACTTCTAGCTGATTTTTAAGTATAAAATATTATA TCAGACTAAGCAAGAAATAGATAATTCTTCCCTTAAATCTTTGCCTCTTTTAGGTTAGTG AACAAATCATAATTCCTTGCCCCTCAAGGGACTTTATGTTAGCCAATTCTAGTATGCCAC ACCCCAGTGGGACATGAGTCTTTTTGCCCCTTCCTTTTAGATTTGGTGGTGATTTGCAAG GATAAACACTTGAGCACTCAAGATACTTATGTTTGTTAGTACATGTAAATGGTTAATTCT ACACTGATAGGCACATATTAAATTGATTCTGCTCATAATAAGTTATCTCTTTGTTATTTT AGCACAGCCCTCATGCTTGCCATATGTGAAGGCTCATCAGAGATAGTCGGCATGCTTCTT CAGCAAAATGTTGACGTCTTTGCTGAAGACATACATGGAATAACTGCAGAACGTTATGCT GCTGCTTGTGGAGTTAATTAGTAAGTGTTTACATTTAAAGGCTAGGTGAAATTTTATTGT TTGTTTCAGGGAGTTTTTGAAAGACAGTGACTTAGTTCACTTCATCAGCCAGAAACTAGG CAAAAAGCCAGACTAGTTAGAAGGAGTACTGGGTCCAGGATTCTTTATTTTAGGACTTTC AACAGCTTTATCCCTAGGGATCCTAATGTTGACTGCTTGATTTGAAGTATAACCCCTAGG CTCGGGATAAACACAGTGTCACAATTTTGATTTTTCTAATTAGTTATTTGGGTCTGGAAA TGTCCACTTCGGCAGAAAACCTGATAATGTCCCCTGGGGGCTGTCTTCCATACCTTAATA CTTGAATTTTTAAAAGGAATCTAAGGGGTTCCTTAAGTCCAAGGAAGACATTCATTTTGC ATAAGTCAGAAGGATTTGGGGGGACACGGCCATTCTCTTCTTTTTGTTGTTTCCATTGAT TCTGTTGCTGCGCCGTTGCCATTGAAACTGCCCCTGCAGTCTGGTAATGATTGACCTTTG TGACCAGGATGCCCTTACTAACACAGATCCCTCAGTTTTCATGGTGATCCATATATAGAC TTCAAAGTCATTACAGTTTTTTAAAGTTCACATACATATTCTCAGCCATTGTTTCCAAAG TACCAGCACCCTGCTCTGGCAGCTAGGACTTTTATCTTTTGCCACACACATAGTGAGCAA ATTGACCATTCTCCTCCCACTCAAAACCTGATGTGAAACCCACATCTTAGCCCGGACTTG GCCTAGACCTTCATGATAAGTTATCATTTGAGTGACTTTTTCTATTTTCTCTAGCAAATA TTAGTTGTGAAAGTTTAAGACTGTACGACAGGTTGAAATACTGTTACAGGAAGAAATTAG AGATCCATTTTTATTTTGTTACCAGATCTATATTCCTGGCACTTTATATCCCGTGTAGCA CCATTTTATAGGTAGTGGAAGGTCTCATCTTATTCTGTAAAATCCCATGTCATCTTTCCA AAGTTGTAGTGGGTTCCAACTTGTGGTTGTTCCCTCAAGTGATTCCCTTTTCCTGAAAGT AAAAATCTTCCATGTTACTTGCATCTTTACCTCGAGTTTTTAAAATCTTTTCAAATTCTG CATTACCATGAAGGCATTCAATAGACTTCACTCTATCTCAAGTAAGTTGCTTAGATTTAA CAGAGCTAAGCCTCATCCATCACTGATCAGTCTTCACATATAAAAGTAGGGATTTGTGCT GGTGTCAGGGGTACATATACTAAAATTGAAACAATGTCAAGAAGGTTAGCAAGGTCCCTG CACAAGGATGACACACAAATCTGTGAAGTGTTGCATATTTCTTGCAGTCCCCAAAAGGAC ATTTGACTAACTAGCTCCAAGGAAATGGTGTGAGTCAAAGCAAAATGGGTGACTCCCAGG ATTGCACTTGTGATTTTCATACAAAAAATATTTATGTAAGGTGATCTATGAAATGAGATG TGGTAACACATAGGATCTTGTGTGCAATATGTTGTTAGTAGGCCTCTCAGAAATGAGAAA ATACCAACTTGCATCTTGTTTGTGGAACTTACAAAAAATAAAGGTAGGGTTTTGTGTTCC ACAGCAGCTGGAAATGAACATCGTGACTTAAGCATCATTCTAACAAAGATTTGTTGATTC AGGTTTAAGGAGGTAGATAAACAGTAGTAGTAGTCCAAGCCAGGTGCTGAGATCTGTTAG TTTTCTGCCCTTGGTGTGATTGATGAGGTCGGTAATAGAGGATAATCAGGTTATCCAATG TAATGAATTAATATATTTACAAATAAATTTCATTACAAATTATAAAATAGCTTAGATGCC TTGAATTACAAGCCACAAAGAATAGAGCATCTAATAACCAAAAGTAGGAATTAATAACAG AAAACTGCAACATTTCAACATTACAACCTATGAAGAAACACTTTTTTTAAAAAAATTAAA TTTATTTTTTGTAGAGACAGGGTCTCCCTGTGTTGCCCAAGCTGGTCTTGAACTTCTGGG CTCAAGCAATCCCCCTGTCTCAGCATCCTAAAGTGCTTGCATCACAGGCATGAGCCATTG CACCAGGCCAACACATTGGGTTTTATTGGGAATTTTAAAATAGTTTCAGCAATAAGATTC AAGAATAAATTATTTCATTGCTTCACTATTTCTTTGAGCATTTTAAAAATGTTATCTTGT TAAATCTTTGTAATAACCTAGTGAAATAAGTCTCTAAAATCCTCATTTTTAGAAGACATT GAGCCTAAGAGAAGCAACTTGTTCAAGAAAAAATACCTGTTGGTAACTGCGCTAGGACTT TTTCTGAGTTAGGGACATTTTCCATTAAGCCAAGCTAACTCTAGTTAATTTACTGAGTTA TACTGCCCTCAATTCATGAGTATTTCATCTTACTTTATTTATTATTTAATTAGAAGCTTA ATAAGTTCATAGAGCTTACAAACTTAAAGTCTGTGAAATAAGTAACATTCTGATGTTAGC TCTGATATTGTCTGAAATACTCTAAGAACTTAATAAATTTGGTAAATGTTTTTTATATCT TGTTAAAATAGTAATTTTATTTATTACATTTTTATACATAGCATTCATCAACAACTTTTG GAACATATACGAAAATTACCTAAAAATCCTCAAAATACCAATCCAGGTAAGACTTCGGAT AGCAAACTACTCTTGATGGTGCTACCATAAGATTAGGGAAGTGCTGATCACAAAAAAGCA ATTCAAAAAGCAATGTGCAAATAGCATGTGTTTACATATATACATATATGTGGGTGTGTG TGTGTATATATATGTATACATAGCTTTGATTTATTTTTTAAATTTATTATTCAGAATTAG TTAAGAATTTAGGTGTAGGTAGTTTATAATCTCAAAAAATATTATCTGAAAAAATATTTA ATTATGGTCCCTAAAATCCTATATAATATTTTGTGTATATAGGTAACACAATTTTTAAGT TTGTATATTGTTTGATTCCTCAATTGTCATAACAACTTAGACTTGTTATACAATGTATAA TCCTTGGTGTGATTGATGAGCTCAGTAACAGGGGATGATCAGGTCATCCACTTTAATGAA TTAATATATTTATAAATAAATGTTATTACAAATGATAATTAGTTTACATGCCCTGAATTA CAAGCCACAAAGAATTGAACATCTAATAATGGAGAGTAGGAATTAATAACAGAAAACTGT AACATTTGAATATTATAACCTGCGGGGGTCTATCCTGCAGATCCCGGCTGCATGACGGAT GAGACACATACCCAGACACCCATATTCAGTGAAAGAGCAGCAAGGGTTCCGAGCCCATTA CAGACACCAAGGAAGGTGCTGTAAGGAGTCAGCAGCCACAACCCTGGCAAGCTGGCCCTG TGGGCATTTATTAGCAAAGTTTTAATGACAAAGGCTTTGAGTCAACATACCTGTGGGTAA TTAATCTGGTCACCCCACCCCAGGAGAGCCATCCTGCCCATGGGTGATCAAAGGGGAGTC TTAAGACTGCATGAGTAAACAAGCTATTTAGATAAACTACTCTACTTTCCTTTGTACCCA CTTTAGGCTATTTACTCAAGGTAAGGATTAGACTGCTTTCAGCCATAACCCTATCTTGAG ACTTTTACAAAACCTTCTGGCCTTCCAAGGAGATTTGTGTCTATGTCCTATAATGTCATC TTAAAATGTTTCCCACAAGCCTGATGAACTCACACAATAAGCTATGAAGAAACATGGTTT TATTTATTTATTTATTTATTGTAGAGACAGGGTCTTCTTATGTTGCCCAGGCTGGTATTG AACTTCTGGGCTTTATTTAATTTTTACAATAAATGGTTTGCATTTAGTAAATGAGAGTTA ATTACAGTTGAATCTTGAGCAATATGAGAGTTAGGGTGCTGATCCCCCATGCAGCTGAAA ATCTGCTTCATATGAAAATCTGTTTCTTTTGACTCCTCCAAAACTTTGCTAATATTCCAC TGTTGACCTGGAGCCTTATTGAAAGCATAAACAGTCAATTAAACACATAGTTTCTATTTT ATATGTACTATATACGGTATTCTTACAATAAAGTGAGCTGGAGGAAAGAAACTGTTATAA GGAGGAAAAAATATATTCACTATTTATTAAGTGGAAGTCAATTATTATACATAAAGGTCT TCATTCTTACTGCCTTCATGTTGAGTAGTCTGATAAGGAGAAGGCAGAGGAGAGATTTGT CTTGCCATCTTGCAGTGGGAAAGGAAAAGAAAAATCTATTAGTGGGCTCCTAGAGTGAAA ACCCTTATTCAAGGATCAACTGTGTGACAAAGTGACTTGTGTCACTAAAAAAGTAACTAT CTTTAGAATTTGGAATTTAATAATACTTTTCTGGCACCATAAACAAATGTCAGCAAGAAT TACAAAACTTAGCCAGGGTGCATCAGTACCAATAGGAGATTATCTTTCAAAGATACCTAC TGAGTGCAGAAGTCAGAAAAGCAATTCTTTGTTGAGAAGCGCAGGTTATGTTACGTAGTC TTGTACCAACAAGGTCTCACTATTATCAACTTCATTCCGTCTAAGTTGAAACCAAATAAG ATATATTTACTTCATTAGAGCAAGGTATGTTGTTCTATCTACTGGATAATTAGTGTGTTA ATAGTAATTTTGTTACAGCAAGATACTCTAATAGCCAAAATATTATCATTATAAATATTC AAATAGCTTAACTCTAAACACAAAAAATTATAAAAAAATTACAAAAACTTTTCACAATAA TGAAAATGCTACTGTGATACCTAAATGTGACACAATGCATTGTACAATATGAACTGTATG AGCACATCTTTATTATATATTTATCAAAGGACCTCTATAAGTTAGGTTTGGCAAGTTGCA GGAGACAAAGATGGAATACACATAGTTTGGGTCTTTAAGGTGCTCATAATACAGAAGAGC TGTGCCTATTGAATTTCTGCATTTTTCCAACAGAATTTCCTTAAAAATGTTTTTTATTCA TTTATCTGCTTGTCCACTTAACAAATAACTGTCAGGTATCTTTAAGGTACTAAGTATCTT CCTTGTTATTATCATTGTCATTTTTTATTTGCTTCTTTATTAAGATACTAAGCATTTTTC TTATTATTATTATCTTTTTTATTATTTATTACTTTATTTAGTGTTTACTCTGTGCCAGAA CCCCTTTTGGAGCTTATAATTATTACTTACTATGTCATGCCATTACCATATTCAGCATGT GTCAGAAATTTTATATCCAAGGTGAAGAATTAAAGCTTTAAAATGTTTGGTAGTGTCCAG GCACAGTGGTTCACTCCTATAATCCTAGCACTTTGGGAGGCCAAGGCAGATGAATTGCTT GAGCTCAGGAATTTGAGACTAGCCTGACTAACATGGTGAAACTCGTCTCTACTAAATACA AAAAATTAGCCAGGTGATGTGGCCTGTGCCTGTAATCCCAGCTACTTGGGAGACTGAGGT AGGAGAGTCGCTTGAGGTAGGAGAATCGCTTGAATTGCATTGAGCTGAGATCATGCCACT GCACTCTAGCCTGGGTAACAGAGCAAGACTCCATCAAAAAAAAGAGAAGAGAGAAAAGAA AAGTTTGGTAATATTTAAGGAAAGCATACAGAATAAGTAGAAGTTTGCCAGGTGAAGTCA GGAGGATGATATTTAAGCAGAAAGAAAATTTAACCAGATTGTGTGTTTGGCAGAAGGAAC ATCTACAGGAACACCTGATGAGGCTGCACCCTTGGCGGAAAGAACACCTGACACGGCTGA AAGCTTGCTGGAAAAAACACCTGACGAGGCTGCACGCTTGGTGGAGGGAACGTCTGCCAA AATTCAATGTCTGGGGAAAGCAACATCTGGAAAGTTTGAACAGTCAACAGAAGAAACACC TAGGAAAATTTTGAGGCCTACAAAAGAAACATCTGAGAAATTTTCATGGCCAGCAAAAGA AAGATCTAGGAAGATCACATGGGAGGAAAAAGAAACATCTGTAAAGACTGAATGCGTGGC AGGAGTAACACCTAATAAAACTGAAGTTTTGGAAAAAGGAACATCTAATATGATTGCATG TCCTACAAAAGAAACATCTACAAAAGCAAGTACAAATGGTAAGATGCTTGAGTGAACTTT GCAGGGTTTATTGGCACTTTGGGTTCCCTAGTGAAAAAAGTGTGATATGGGAGTTGTTGG GAATGTCTTGAATATCTAAATAAGGCAAGCTTAGGCAACACTTTTTAATAGTGTAGAAAT AAATAGATCTTATTCTGTAGGCCCTGGAAAAATTCTCACAATACTTCTGGTTGTAAATAC TAGATGAACTAACTAACAGTGGCTAAAATCATAGGAACCAAAGTTGTTTTGGTAGTACAG GGATATCATAGGATCCCTTTTGTATTTTTTATTTTATTTTATTTATTTAGTTTTTGAGAT GGAGTCTCGCACTGTTGCCTGGGCTGGAGTGCAATGGCGCGAGCGATCTCGGCTCACTGC AACCTGCGTCTCCTGGGTTCATGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCACCCACCACCACACCTGGCTGATTTTTTGTATTTTTAGTAGAGACAGGGTTCCA CTATATTGGCCAAACTCCAACTCCTGACCTCGTGATAGCCCCGCCTTGGCCTCCAAAAGT GCTGGGAATTCAGGTGTGAGCTACTGCGCCCAGTCAGGATCCCACTTTTGGTTGGCTAAT TAGCAACAGCTCCAATCATCATGCTCTCTCAAGACAATATTTAAAGGCTGGAAGGGCTGC TTTGTTCACATTTTTCTTTTAAATAGAGAGAAAACTTGGAAGCTTGCAATAATCTTCCTG TAACATTTTGTTGGCTGGATTATACCACATGCTCATTTCTAAGCCAGTCACTAGGAAAGC AAATGTAATTACTGTGATTAGCTTAGAAGAATGATTTCTATTTTTGAGATGGAATGGGGG TAATGGAATAATGAATATCTAAATAAACTTGTGTTTCTGCAGCAAAAAAAGAATAAATAA TGACTAGGCATAGGAAGCCAGTAATGTTTTCTGCAGGGATTCATTGGAAAGGTTTGAGCA GGGGAGTCACAAGATTGGATCTGAGCATCAGGGCATTCTGGTCGTGGTATAAGGCAGAGA TTGGCAAACTTTTCCTGTAAAGTGCCAGATAGGAAATATGTTAGACCGCTGGGTGTGGTG GCTCACGCCTATAATCCCAGCAGTTTGGGAGGCTGAGGCATGTGGATCGTGAGGTTAGGA GTTCGTTCGAGAACAGCTTGGCCAATATGGTGAAGCCCCATCTCTACTAAAAATATGCAA AATAGCCAGGCTTGGTGGCACGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGGAGGA GAATTGCTTGAACCCAGGAGGCGGAGGCTACAGTGAGCTGAGATCGCACCATTGCACTCC AGCCTGGGTGACAGAGCAACACTCCATCTGAAAAAAAAAAAAGAAAAAGAAAAAGAAAAA GAAATATGTTAGGCCATGTGTCTCTATAACAGCTATTGAACTCTGCATTGTAGAGTGAAA GCAGCCATAGATAATGTGTGAGCAAATAGGCATGATTGCACTCCAAGAAAACTATGTATA AAAAACCATTTGGTAAGCTGAATTTGGCCTGTGATACACAGTTTGCTGGCCCTTCACATA GAAGATAGATGGAGGGTAATTACATAAAAAGATTTAAAGACAAAGTAAGCTTTTGTAGTA GTTCATGCTATAGTCTTTTTTTTTGTCACCAATCTGTGGCCTAGTATCAGTCTATTATGA AAATTTGACCCTTCCAGGGTAAAAGGAATCAAGTTCAGAAGCTCAATTTACAGATTTAAA CCTGTATGTCTTTCTTTGCCATTATTTTATTTTGATTTGTTTTACTGAATTTTTTTTAAC TTAAAAAATAACGATAGTAATTGGTAGGGTTTCTTTTTCACTGTGAAAGCCATCAGTTAA GGGGCCATGTCTAAGTAGGAAATATAAATATAAAATAATAAGTTTGTATTCCCAGTGTCA CTGGAAAGATAAAGCAAGGGCAGAAAAGAGGTACAGTTAATATGGTTTAGTTATTATTGA GTTTAAAAAGCTAGGGGACAGAGAAAATCTCAGGTCTTAAGTTTACAGACTGTGCATGAG CATTTACAATGCTCATGGGGAAGGAGTAGAAAATTGTCAGGTCAGGGCTGGGCATGGTGC CTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGCAGATCATGAGGTCAGGAGATGGAGA CCATCCTGGCTAACACGGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGG CGTGGTGGTAGGTGCCTGTAGTTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCATG AACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATCTCACCACTGCACTCCAGCCTGGGTG ACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAGAAAAGAAAA GAAAAGAAAATTGTCAGGTCAGCAGAGAAGTGCAAATAGTCATGGGACAGACCAACCATT TTCTTTACATATTGAGTTCAATGAAACATTCATGTGGGATATTTTCTGTAGGTAATTGGT TTATACGTATTTCTAGCTGGAGATAGAACTCTGGTTGGAGATGTAGGCTTAGAATAATTT TATTATAATTATTAGGCAAAGCCATAGATCTCAATGAGCTTATCCATGATGCAGAAGATG TAGAATAAGAAGAAAGCCATTGACAAAACCCTGGGAGTATCAACATTTCACAGAGTCAGA AGACTTGGTAAAGGAGATTGAGCAGTGGCTAATGAAAAGTAGGAGAGGAGTTACTTTTAA ATGTGAGAATTTCAAGCAGTAAGATTACTGAAAAGCCAATTAGATTTAACTTACAAGTTC TTCAGTGGTAATCTGTTCAAAAGAATTATTTTAGGGTTGTTAAGTATACTGTTGATATGG TTGATATTTCTGGTGTCGAAGAAAAAATCTCCCAAGATCCTACCTAACTTTTTGTAACTG AAGCAGCCAACATACCCAGGGTCTGGAAAATTGTCTAGACTGGTAAGTACACATGCCAAT ATTTTTCCAGAATTGTCAAAACCTAAGAGTAAAGTGTGAGGAAAAGTGTTGTCTTTTTTA TCTGCTTCTTGTGGAGAGTGGAGATCTGTGTTGTGTCTCTCTCTCACACAAACATAAACA AACACACACAAATAAGTACAGTAATTCACCCTTATCCATGGGGGGTATTTTCTAAGACAC CCGGTGAATGTCTGAAACTGTGAATAGTATGAAACCCTATATATACATGTTTTTTCTATA TATGCATATTTATGATAGTTTAATTTATAAATTTGGCACAGTAAGAAATTAAGAATAACT CATGATAAAATAAAACAATAATAATACATTGTAATCAAAGTTAGGTGAATACGGTCTCTC AAAGTGTCTTGTATTGTACTCACCCTTCTTTTTCTTGTGATGACTGTGAGATGATATAAT GCCTATGTGATGAGATGAAGTCAGGTGAATGAGGTAGGAGTTGTCATGTGGTGTTAGGCT ACTAATTATTTCTGGCTATCTGACTACATATCAGAAGGTGGATCATCTGCTTCATGTGAT GGTGGATCATTGAGCCATGATAATGTTGATGGTTGGGACTCAGAAACAGACCATTTTGAT GGGCAGATAGCATATGCAAAGGAATGATTCATGACCTGGGTGAGATGGAAAATGATGTCT TTATATTTCATCATACTCCTTAGAATGACACATTATTTAGAACTTATGACTTGCATATTT CTAGAATTCCCCATTTAATATTTTTGGACTATGGTTGACCATGAATAACTGAAATCACAG AAATCAAAACCATGGATATTATATTGTGAAATCTATATTTGGTCTTCAACACTGTTTTCT GGCGTACAACTCATAGAATGTTTAGAATCTCCAAAGTGATGTCTTTGTATGCTAATAATT GAGTGATGGCTGGCAGTCCCTAGGTAGCTTCAGGATAGGAGCTGGTCACAAGAAAGAAGA AGACATGATGTGTTGGGACTTTCAGCCCCACCCCTCAACCTCCTAGGAGGTGAAGATTAG GTCAATTACCAGGAGCCACAGATTTTTTTTATTCATGCCTATGTAATAAAGCTTTCTTTA GAACCCAGAAGGACTGGGATCAGAGACCTTCCAGATAGCTGAACATATGGAAGTGTTTGG AGGCTGATGTGCCCTGGGAGGGCATGGAAGCTCCATGCCCCTTTCCTATAACTTGCTCTA TGCATCTCTTCATGTGTCTCCTTTGTGATACCCTTCATAATAAACTGGTAAATGTGTTTC CCTTAGTATTTGGGGCACTCTAGTACGTTAATCAAACCCAAAGAGGGAGTCATGAGAATC CCAACTTGAAACCAGCTGGTTAGATGATTCAGAAACCCACATTTGCAACTGATGTGGGAG GGCAGTCTTGTGAGACTGAGCCCTCAGCCTGTGGGATCTAACACTATTTCTAGATAGATA GTGGAATTAAATAGAGGACAACTTGCTGGTTTCTGCTACAGAATTGTTTGCTTATTTTTT GGTGGACAAAATCTTCCACACATTTGGTCACAGAAGTCTTCTGTTTTGATGACTGTGGCA TGAGAGCAGAGGGAAATCATGTTGTGTGTGTTTCTTTCTACACATAGAGCAGATAAAGAG AGACTACTGTGTACTCTGCTCTAACTGCTCTTAGTTCATTTTTCTAGAAATTATACTTTC TAAGGTTGACACTGTCCACTTACACTAATTCTGATAATAATACAATTTTCTGTCCGTCTT ACAGGATTCTGTTTGGATTATGACTATTGTATACTGTAGCTCACTTGTAGAGATCAGATT GTGATAAATTCTATTTTTCCGTGCATTTGAGAACTATAAAGGAGGGGAAAAGTGTTCTTA ATGCATTAATTTCCTACCAAGAGTATACTTAATAATAATTTTACTATAGTCTCAAGGTAT GGTCCCAAAGGAAACCTTTATATCAAATCATCTGAGTCTTCATAACAAAGTGTTGGAATA TTATGCTTTTTTAAACAAGATCTGGATCATGCACGAAAATATGCATGATTCTTTTAAATT AAGTTGAAGTCTCGCAATGTCTCCTAGGCTGCTTTCAGACTCCTGGGCTCCTCAGGCGAT CCTCCTGCCTCACCTTCCCAAGTAGCTGGGATTACAGGCATTTGCCATCGTGCCCTCTTA CGTTGTTAATACTCTGTATTTTCTATTTATATTTGTTAATTTAATGTATTTTACTTTTTT TCTTTAATAGTGGATGTGAGTTCTGTAGAGCCTATATTCAGGTAAGACTTTGCGGTTTTT TAAAACGAATAGGTTAACTCAGAAAACATAGAGAAAAGAAATCACTATCTGCTGAGTATT CTACTCTGGGCTAGACAACATATTATGTGCTTAATATTTATCATCTCACATAGTCATCAC ACAGCTTTGCAAAGCATCTGTGCTACTGTCACATACTTTGTATTAAACAGGCAAATGTGG TTCAGAGAGGTTGATTAATTGGCCTATGATTCATAGCTAAAAAGTAGCTGACCCTTGAGT TTGCCATCTGCCTACTTTGGTCCCTAATCCCTTCTCTTCTCCCTCAGCATAGATTGATGG AGACCTCTGCATCACTGAGATCAAGGTACAGGTCCAGATTGGATCAATTCACAAAGTTAC ATTTTGTTACAGGTTAACTCTTTTTAGAGTTTTCTCTTAGAACACTCATTCATCAAATAC TTTGTTCTAACATGTTTAACTGTTAAAGCGGTAACCAGTACCTTGTTATTATCATCAAAG TGTTTAGAGCAGATCTTACTTAGCTGTGGCCACAAGACATAGGCTTTTGTTTCATAAGAA GACCAGGTAAATCTATAGATGGATTATTTTACTCTTAGTGGAGAATAGATATAGATATGT TATGTTAATCATATTTAGAGGCTATATCTTATAGAATTCTCTATTGACTGACTTCCAAGT TTAGTTTTTCTTCAAAGCAGTTCCCTGCCTAGTTGCAGGCATTTTTCATTTTTTTTCTAG AGTCTTTTTTTCTTCTTCCATGACTTTTCTATAATCCTTTCCTGATTACTTTCTTCTCTG CTTTGCTTGGTGTTCTTTTCTTCTATTGTTTTATTCCTTTCTGCCAGCACCATTTTTCTA TAGCTAAAATAAAAGGCACGTGGAATTTTAGGATTTTAAGGACTCTTGGAGGCTAATCAA AATACTTTCATATTTCAACATGTATTTAATATCCTGGAAAAATGGTTGTTCAGATGGAGA GTCTGAAACTCAAAGTGACTTATTTAAATATAGGAGGTAGGAGAAGTAATATTTAAACTG ATTTCAAAGCCCATTACTCTTGTTTTTATATCATCATGTAGGTGAGTGTTTGAATAATAG GAAGAGGGAATGGGTCTAATTAAACAAATGGAAAAGGATAAGAATGGAATTAGCTGGAGA ACCCAGTGGAAGTAGATAAGAATGGAATTATCAGGGAAAGGCCAAGTTTGAAAAGAAACA ATCCCAGGATTGGTAGGAGTAAGGGTTTTACCAAAGAGATCAGAATGTTGGATTTTATGA CAAGTTTGATTAAAGATAAATTAGAGGATCAAAAACACAGAAGACATTGGGAGTTATCTA GAAGAGCATACTAAAATAGGGTTCAAAGACGTCCTGAATAGGTCACTGCTTTTTTGCTTG TTTAATTGGAGGAATGGGCAAACTTCAAGCTTTCTATTGAAAGATAAAAAAAAAAAGAGC CACTGGGAAAGGTCTCTACAATCCGATAGAAATGTCCTATTCTGTTCTTTCACCCCAAAT CTCACAAGAGTGGCTTAGAGCCCCTTGAATGCTAGGGGATTAAAGGTTGCTGAGTCACAT AGATCTGTGGCCCAAGGCAGATGTCCCCTCCCCTTTGTCTCTTTTCCCAAGCCTCAGATG TCCTACCCATGTACATATAAAGCAGGGGTAAGATTGACTGGCAAGTAAGTCGTGGTTCAG TTGGGTTTTTGGTAACATGCTTATGCTGGAGGTGAATGACTGACTGAGACTCCATTTCGT TGTTTTTCAGGAACAGGTGAATACAGAACTTCTTGGTTGGTCATTGAGTTTATCTTTTCA GTAGTCTGTGCTTTGATGAGCTGAATATTTAAAGGTTGGAGACTGCCATGAAGCCCTGCA GAAGAAAGATCTGGAAGTGAGAGAGACACTTTCACTATATATAGTGGCTCCCACTTCCAG ATCTTTCTCTCTGTATATATAGTACTTAGAGAAATCCAACTATCAGGTCTCAGTTTTTCT AGCAGTCTCTCTCCTTGGGTATAAGTACCTATGAAGATTTTTAAGGCTTTGCTAGTTTAT GTAGACCTGAACAAGGAAGGACAAGTATAAAATAAGTAGTTAGACTTTCTTACTTTTAAT GTTTCAATTTTTGTGAGAAAATATTCCGAATAACAAATATACATTTGCAACTTGAAATTT GTAGGTTCAGCTTTTCAACATTTCAAATATTTCAGGGCACTGTTTTGTAGTGTTTCAGGG TGAAGGGAAGCAACAGGGCCTTCTTAAGTGGCTTTTATGTTGAAAAACAAAGAATGTCAT TTTCCAGTGACACAGATTAGTCTTTGAATCAGAGATAGACAATGGATAAGGGACAAGGTA ACTGTATCTTTCTTCCTTATTTTAGGTTATCAAGTTTGTTCCAGTTTATATATCAAAAGT TATGTCAGCCATTAAGTAGATTTCCAGTTCATCATTGAGGACAGTTTGTGAGGATGAATT ATACTCAGGGTATGCCAATTATATTGGCAGTCACTATTTCTTATGGAACTAAGAGTCAGT CTTTATTGTATGTTTTAGGTTGGGGAGGTAGAGTCAAAAATAGGTAACTAAAATCATTTT TAAAAACAGAGGACATATTTTAATTCTACCAAGAAACATGATATAATATACAGAGGACTG GTCTTTCCCCAGATTTTGTTTTTTGTTTTCATTTTATAGAGTGAGCACCAAGATATGAAC TAGCAGATTTTCTTTTTAAATATATGAATTTGCTCATTTATGTTGTATCATTTTTCTTTA AAGTCTTTTTGGCACACGGACTATTGAAAATTCACAGTGTACAAAAGTTGAGGAAGACTT TAATCTTGCTACCAAGGTAAAATGTTCTTTTGTGAAGTTGATTTTCTCAGTTGCAATATA TTTCTGTATAGTATTTCTTAGCAGTGGTGTATGTATCATTATTTCATGTTGGTAATATAA AGTTGGTCAGATAAAAACATTTTATAGAAATAGGAGTAGTTGATTTAAACAGTTTTTTTT TTTTTTACTTTAGTAAATAACAAATGATTGGTAAATACTTTGAGGGTGTGAGGGCCGAAA AATGGAATGGGCTGGAGAATACATAGTGACAGGAACATTATACTAGAAAAAACTTTTCCA CAATAGAGAATATATAAAATCTGGTAAAGATTTATTTGGATAAGTAAACTTACTGTGACT TTTAAAATTATTCTTTTGTAACTTAAAACAAAATTCATGCTTAAATTTGTCTTGATGGAC CCAGTTTCTTATTATAGTAATCAAGGAATCTCTCTGATACTGTTCAGTTCCGAAACTGTG CCACATAGCATATAGGGTTTTTTTTTTTTTTTTTTGCATGTATTATTTTGATATCACGTA GTTTTCAGGAGAGAGCTTTTTCTCAGTTTCTCTTCTTGGTTCTTTAATTACACCAAAATA ATATTAGAAATTGTGAAAATTTATTTGGGCATGGTGGTGCATGCCTGTAGTTCCAGCTAC CAGGGAGGCTGATGCAGGAGGATTGCTTGAGCCCAAGAGTTTGAGACCAGTGTGGGCACA TAGCGAGACCTTATCACTAATTTTAAAAATAATTGTAGAAATTTAGAAATGTAAATTCTG TTTCTCAGAATCTGTATTATTAAGGCATGCCAGTGTGTTTTCTAAGTTTTTCATTAAAAG TATGCTTTAAATTCTTCATCTAAATGAAGAATGCAGATTTTACCCCAAGTAAACAACCAG TTCTGGAAGCAGAGACTCTGAATAAGCATATAGTAAGATTTTAATTTCAGAATTTTTAAA TTGCAGTTTTTAAATATATTGTTCAAAGATCTTTGATCACATTTGAAAATCTTAAATTAT GGAAGATTTTGTATTTAGTTATTTAAATAATCATTTTGGAGCTCTTGCATCACTATGAGA TACTGCAGGTTAGAAAACATACGTGTGTGCATCCTAGTGTACCCAGAATACAGTCTTGCC TATAAAAAGATTTTAAGAGGTTTTCAATGTGAATAAATAAGCTGACAAATGAATTTTTAT ATAATGGAATATTACAAGTGAGATAATATGCATGATATATCTTATAATTAAATCTAATGC ATTTCAAAAATATGGCTTAAATTTATATTTTCTTTTAATATTTAGAATGCATAAATTCAT GTGAAAATATGTCTCAAATAAGAAGACAATCAGAGATATGTAGTAAATAGGAAAGAAGAT TACACTATATTTTCTAGTATCCTCCAAGTGGAGTTTAGATTAAAATAATTTTAATCTCAA CTCATGTTCTTTTTTTTTTTTTTGAGACAGAGTCTCTCTGTCATGCAGGCTGGAATGCAG TGGTGTGATCTCGGCTCACTGCATCCTCTGCCTTCTGGGTTCAAGCAATTCTCCTGCCTC AGCCTCCTGTGTAGCTGGGACTACAGGCGCATGCCACAATGCACAGTTAATTTTTGTAAT TTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGATGATCTCTATCTCTTGACCTCATG ATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGCTTGAGCCCCCGCGCCCATCC AAAACTCAAGTTCTATTAAACATATCTTGTCAAGGAATACATTACTCTAAAATTCTGATT ACCAGTACTTTCTTCAGGTGAAAAGTTTATGGAACATTCCATTTTAAATTTTTTCTCTCT CTGTAGTAAGAATGTTCCCGCTTTTAGGTATTGGCTGAAGACCATGTTTAACTAATTGAA TGTCTTATTATATAATAATAAAATTAAAATCTTTATTACCCAGGTATTAACAAATAACTA ATTGTAGTGTAAATACTGATCAGCATTATAGGAATATATTATGAACAAAAGTCTGTACTT TATGTGTTTCATCATATATCTTATAGTTGTTGTTTTTCATTTTATTTAATGACTGAAGCT CATACTTGATTGACTGGTCACGTCTCTTGTTTGTTTCTCCCTCCTCTTTCACCTTTTTAA AAATGATTTGCCCCAGACTTTTTTTCTCACAGAATACATTTCTTCAGTGTCTGCTTTTTA GAGCATTGCTGTCTCAATTGTCAGCATATTTATTTACAGGTTTCTATTTAGTGGCTATGT ATGATTTTCATTAATCAATCATTGCCCTCTCCATGATTTATTCTTTTTTTCTCTGTTTCT TGGAAGAAGCAGAATTTATACAATTATTTATACTTAGCTTTTTGCCGTTCAGAATAGAAA CAACCTATACTATTTCAATGCAAACCCAGTTAAATAAGGTACTATTAAAAACTAAACTTT CATATTTTTCCACACAAGAGGTAATTAATACAACTGTAAATTAGGAAGAGATATTGCAAA ATATAACATGTAATTTAACTTTTTAAATTTTAATTATTTCTACAATACTATAAACTACGT AAGAGTAAATTTTTGTTCTAGGTTATTTTAGCTAAAAAAAAAAAAAATCTAAGGGCCAGG TGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGCCGGCAGATCACGAG GTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAACCCCATCTCTACTAAAAACACA ACAAAGTAGACGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGC AGGAGAATGGCATGAACCTGGGAGGTGGAGCTTGCAGTGAGCCCAGATCATGCCACTGCA CTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAACAAACAAGCAAACCAAGAAA TTATTTTCTGACATTTATCAGAACATACTTTATAATCATGTATCAAGTAGATAACAGCTG CATAGTGCAATTCTGCTAATTTGCAGGATTAATTTTGAAGCCAGTGTAGAATAGTGCAAA AGAAAATAAGGCTTAGAAGGCACTAGGAATCTATTTAGTTCTGAAGTTGTTTGTCTAAAA ACTAAATAATTTCTCTGCATTGATTTATGGGCAATTATATGATTCTGTGTATATCTAGAT GTACAAAAGCTCTAATTGGATTCAGGGAGAAAGAGTTTAAACTGTAGTCTTAGTCTTGCT CAACTTGGAACTTGAAAAGATAATGCCTGGGACTTCAAAATATCAGTATTGGTATATTTT GATTATCCAGTATAGATCTGAAGGAACATTTCTGGAGTTGGATAAACATGAGAAATAGGA CACCTGTAAAACTATAATAACAACAATTTGGTCGAGTAGTATTTTAATAAGTAGACATTC TTTTCACAAATAGAACTCTTTGAGTTTCTTTGTGGCAGCCATGTTTGCAGCCACATAGGT ATCAAATAATAATGATGTATTCCAAGGTCACAACTGTGGATGTGGAAGAGATAGCAAAGG CCTCACCAGTTAGGTAGAAGCAGCAGCTGCATAGTGGTAACAGCAATGAGTGGATGTCAA AAGATAAGTCTGTATTTGGTTCTGACACTTACTAGCTATGGGAACTTGGAAAAAATCAAT TAACTTAACCAAATGCAACTAACTTGGTTTATAAAAATAGCGCTCATATCTACCTCTTAG TTGCATGTGATGAAATAATGTTTTAACAAATGTGAAAACATTTTTTAAACTGGAAAGTCT GTATACAAATGTAAGACAAAATGATCAAAGTGGCATTTATGTGAAAGCAGTATTGTTAGC ACAAGAATGGGAAGTAAGAACAGGCATGTGGATTTCTAATTTTGGGTAAGGGGATGGTAA CTTTCAGCAGGCTACTACTGCAGATTTTCCATAGAAATATAGCAGTTTGGAAAGTGAGAC TTTCCTGATGAGATTTTCAATATTTTGACCTGGAGTAATTCCTTTCTGAGTACCAACTGT GTGCTAGGCAGTGAGTCTGAATATCCAAGATGAGGGATTATGCTGTAGTAGTAGGAAGAG AATAACAAATAAAAAACACTTATAAGCCACTATAACTTTTTCTTTAAAACAAAACAGAGA ATGTTCAGTTAGAGAAAATTGGAGAACTTTATAATTAGCATGCGTATGGGAGTGGCAGTG GAATTCTATGGTCAGAGTAGATCTTTCTGAAACTGCCATTTAATCTCCCATCTCAAAGAT GAGGAGTAAGCCATATGAAAGTCTAGGAGGAAGACATTCTGAACAGAGAACAGTGGACCA TATTTGTTCATCATTTTGTTCTTAACAACTTAGAATGACTAGCATGCAGAAAGTGGGGTA ACCACCCATGTCATCGTCATCCTCATTTTTCTAAGGTGAAGAAAAGTCTGCAAATATGTG TCTGGCATATGTTAGATGTTTCACGAACACGTTTTTATTTTTCTCTTTTTATGAAGGCTT GCTCTACTTTTCTGAAGTTGTGTATTAAGAATGAATTGCGTACTTTATCTAATGATTGTT TGCTTTCATTTAAAAATAACATAAATATAAGTTTTCCTTATGAATCTTTCCTTTTATTCA AGCAGTTCTGTATCAGCAAAAACTTGTAAAAATCATTCTTATTATTTTAAGCCCTTGTTT TCCTAACTGAATCAGCTTCTACAGAGTTCTACTCCTACTCCGCATGACATACTCTGAAAA TTCTCTTCATGCCATGCATAGTTTTTAACAAAAATTCTATAATTATGCATATGTCAAGTG TTTAATCATATTGTGTTCTGGTTGAAATGCCCTATTATTTTTGGTGAGGACTACAGAGTA AGGCAGATACTTTGAAGTTAATTCCTTTTGAAATATGTACACGAGTGAATTTTTTATGAA TATGATTTATTTTCCATGCTCAGTAACCCAGTCAATAGCCACATGAAGATAAAAGGTAAG TGTGATCTACAAAGCATACGTGAGGTTTTCTCTTGAAATGTTTTGGTTTTCAATATGTGA ACAGCTTTAAATCTAATTGCCTTTAAAGTTAAAAAAAAGTTTTAATTATTTTTTTTTCTT TTTTGAGACAGAGTCTTGCTCCGTCACCATGCTGGAGTGCAGTGGAGTGATCTCAGCTGA CTACAACCTCCACCTCCCAGGTTCCATCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGG GATTACAGGCACCCACCACCACGCCAGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTT TCACCAAGTTGGCCAGGGTAGTCTCGATCTCTTGACCTCGTGATCCCCCCACCTTGGCCT CCCAAAGTGCTAGAATTACTGGCATGAACCACTGCACCTGGCCCCATAAAAAAGATTTTA AATAAAAAATATTGATGCTTGTCATTTTTATTATTTTTAAATTGAAATTATTTATTGATG TGGCTCAAGCCATAATCCCAGTGCTTTGGGAGGCTGAGGCGGGCGGATCACTTGAGGTCA GGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACGCCATCTCTCCTAAAAATACAAAAA ATTAGCCAGGTGTGGTGGCTCCTGCCTGTAGTCCCAGCTACTCAGGAGGCAGAAGGAGGA GAATCGCTTGAACCTGGGAGACAGAGGTGGCAGTAGGCCGAGATCACACCACTGAGCCAC CCTGTGAGACTTCATCTCAAAAAAACAAAAAAAGGAAAAAGACAAATTATTTATTGGTAT TACCTTTAACAGATTATCTCTAAGAGTGCTGCACAGAATTATACGTGTTTACCTGATGCT ACATATCAAAAAGATATCAAAACAATAAATCACAAAATAGAAGGTAAGAACCATTTTTTA TTTAAAACATCTTTTGACCAAATGTTTGTCTAAATTCATGAGGACTGATATACTCTGACA GCCAGAGAAAATTATTTTTTAAATGCATAACACGGAAGAACAAAGGCAGTGAAAGTTATG TGTCTTCTCAGGTGTTGACAACAGATTATATTGAGAGTGCCAAAAAAGAGCTGAATTATT AGTTTAAATTCAATATACTGTAAGACCTGAGGAAAGGAGTGAAAGAGGGAATGAAGGCTG AGGAAGACAGAGAGTACAGAGAGTACATGAGGCAACAAGAAATGGGTTTAGGTAATAGAG GATGGTAAAATAAAATAATTCTTTAGCGAAAGATAAGGCATGATTAGAAAGTTTTGAAGA ATATAAGGTGACCTTTCTTTACCAAAATTTGCCAGAGAATTACAGCAAACATGTTTTCAC TCTTGTCTTTCTCACCGGTGGGAAGGCATTAGGGATGGAAGCACCTGACCATGGAGAGTT GTGTTTTATCTGCAAAGGGTTAATATAAGCATATTTGCACAGCTGTGCGTGTATATAATT TGTCATATACACTCGGTATTGACCAGAAGTTTTCAAACTTTAGAAAATCAGCTGAATACC TTGTCAACAATGCATGCTGTGATTCAGCAGACTTGGGATTCTGGAATTTTTAATAAGTTC TCAAGTGATGCTGATGCTGGTGGTCCTTGGACCTCACTCTTAAGTAGCAAGGGAATAGCC TTTCCTTTGGAAAAATCTGGAAGAAGGGCCATTGGATAGAAGGTCAAGACATAACAGGGT CAAGGGAAAGCATTATATTGCTTTTATTTCTGAGTATGTTTCTGACCAGAGGGGAAAAAA GAGGTAAAGAAATGGTAATTACAGATGTCAGATACTACCCCTAAACAAAGAGAAAAAAAG TGTTGGGAAAATTGATTTTAAGAGATGTTGAATGGGAAGAATCAAGACTACAGACGTAGA CATTATTTTGGCTAAGGAAGAGGGATTGTGAGGCAGGACACGGGATAAGAGAGAAGATAG CCAGGCAACTTTCGAGTTTCTGAATAGGATATTTGAGTGAATTCACTTCAGATGCATTTA GAATATTTCTGTTAAATGAATATATTGATTTTCTGCCTCATGGCTCTCAGTACTCCTTGG ACCTTTAATTCCATGAAATGTGGGAAATTTAGGTTACTTACAGCAATCATTTTTCCTAGA AATGTCTAATGTTTCTCCAAGGAGGCCCAAGTTGATTCTGAAGCTATTGTTGCATTGAGG AAAGACTATCTCATTGTAATTAAAGCAGCTTTTAATTTATATGCAGTACAAGTTCTTTAA GCTTATTTATTTAAAACGCATTCACACCAAATATACTGTCATGGCATATTGAAATTTCAA AGGGTTGAACATATATTTCCTAATATCAAAAAGTTAATTTCTTGAAGAATCTTACTTATT GATAATGTTTTTTGAAGAACTGTGTAATAAAGATTGCTTAGTCAATCAAACTAAGTAATA CTAAAAAATAAAAACAGAGAGAATTGAGAGATGATAAGTAATTAAAGTTATCTGAGTGAA TAGCAAATTTCAGACATAGTGTGTTTCATGGGAGAAGAGGATATTATTTCTTTTGTGAGG AAATAATTAATACAAATTAGTCAATTTTTATTGCTTTTTGCATTCTAATGAATATAAAGT TAATTTTTAGATTTTTAAGATTGTAGTTCTAACCAATTGACTATAGAAGTGGTGGTTGTT ATTCAATAGAATATACAGGCTCCAGAAGAAAGTCCACAGATTCATGAATGAAAATAGATT TGTATATGTTTTTAAAATTTATAATAAGGAATGCTCTCATGAATGTATCTGTGATTAACA TTTTTAGATCAGATGTTCCCATCAGAATCCAAACGAGAGGAAGATGAAGAATATTCTTGG GATTCTGGGGTATTGTGTATTATTGCTGTTATTATTCTCTAAAAATATTAATATTGAGTG ATGTGAAAATGCAAAATCAGAGGCTTTGACTTGGTTCTCTTACCACTGCATATGCTCAGA AGAAATTCTGATATTTCTAAAAACATACTTGGCTGGGTACTGTAACTCATGCCTGTAATG CCAGCATTTTGGGAGGCCTGAGGTGGGAGGATCACCTGAGTTCAGGAGTTTGAGACCAGC CTGGCTAATATGGTGAAACCCTGTCTGTACTAAAAATACAAAATTAGTTGGATGTGGTGG TGCACACCTGTAATCCCAGCTACTCGGGAAGCTGAGGCAGGAGAATCACTTGAACCTGGG AGGAGGAGGTTGCAGTGAGGTGAGATTGCACCATTGCACTCCAGGCTGGGTGACAGAGTG AGACTCTGTCTCCAAAAAAAAAATACTTAAAAAAAATCTATGTGGTAAGTAGATTACTGC TTAATGGTGAAATTCTACTAATTTGCAGAATGAGTTTTAAACACTAGTGTAGTATAGTAT AAAAAATAAGGCTTAGAATTCACCAGTAATTCACAAGTTCTGAGGTGAAATTTGGCCAAA AATTAAAGAATTACTCTGAGTCCACCTGTGGGCAAATATATGATTCAGTGGTATATCTAG ATGTACAAAAGTTCTAATTGGATTAATAGAAAAACAGTTTAAGCTGCAGTTTTGTACAAC TTGAAACATGAAAAGATAATGCTTTGGACTTGAACTTATTGACATACGTGTATTGTCCAG TATAGATCTGAAGGAACATTTCAGGAGAAAAATATGCATAAAGAATAGGAAACCAGTGGG ACAATTTGTTTGAGTAGTGTTTTAAAAAGTAGAAATTATTTTTATAAATAGAACTCTTTG GGTCCGTTTGTGGTAGCCATGCTTATAGCAACATAAGTATCAAATAATAATGATGTGTAG TCCAAGGTCACAACTGTGGAAAGACACAGGAAGTGTCTGACCTCTTACATCCAAGCCCCT GCTGCACAGTGGTAACAGAAATGAGATGTCAATAGACAAGTAGATTTTATCTAATTTGTC CATAGACCAAAAAAAAGACTTTTTCTAATATTTGTCTGCTTTCATTTAAACATAACATAA ACATAAGTTTTCCTTACTACTTTTTCATTTTATTCAAATACTTTTTCTATCAGCAGACAT TTTATCAAAAACATTTTGATTATTTTAAGCCCTTGTTTACCTAAATATAGCCGCTTCTAC AATGTTCTGAGTATTCTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTCGCTCAGT CGCCCAGGCTGGAGTGCAGTGGCTGGATCTCCACTCACTGCAAGTTCTGCCTCCTGGGTT CACGCCATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGACTACAGGCGCCCGCCACCACG CCCAGCTAATTTTTTTGCATTTTTTTAGTAGAGACGGGATTTCACCGTGTTAGCCAGGAG ACTTATTCTTAACATTCTCTTTATGCCATGCATCATTTTTAACACTAAATAATTCTATAA TCATGAATATTTTCCATGTTTAATGCAGTATGTATTTGCGGCAGCACTCCTCTCCAGGAG GCACCAGCTGCAGGGAGTCTGTCCCTTGCAGACCCCTGACCCAGGGAAAGATGAATAAAG TACATTGACACACAGATATTCTGCTCTGCCAGTCCAGCTGAGAGTGTCCGTGTGGCTTAC AGACTCCCTGCTGAGTTCTGTGAACAGTTGCCACTATGGCCCTGATCAGCTAGTCAGACT CGCATTTATTCAGTAAGATAATAATTAACAAAAGCTTGAGTCAACACCATTAGAGGTTAA TTGACATTGTGGACTTCCCAAGTAAAAAGCACTTAAGCACCTGTGGTACATCAAAGGTTA GTCTTAAGATTATATGAGTAAACTAGCTAGCTAGGTAAACTACTCTGCCTTCCTTTATGA CTATTTTAATTTGTTTAACGAAAGGTAAAGATCAGGTTGCCTTCAACCATATCCATTACC AAAGTTATGCAAACTTCTCGGCCTTCGAAGAAGTTTTGTGTCTATCTCTATAACTATCTC TAATATTTTTCCCACCAGCCTGATTGAACTCCAACATGCGTTATGGCAGGTAGCAAGTGT ATTGTATTTTGTTTGATGTGCTTTCTTGATTTTTTGGTGCAGAAGATAAAGTAAGATATT TTTAAGTGCGTTACTTTTTGAAATATGCAGATGAGTGAAAATTTGTGTCAATATTATTTA TTTTTCATGCTCAGTAACCGAGTCAATAGCTGCATGAAGACAACAGATAAGTTTTGACCT AGATAGCATATGTGAGGGTTTCCATCAAAATGTCGTGATTTTCAATATGTGCCTATCCTC AAATCAAATTGCCTTTGAAGTCAGAAATTGAGTTTAAAAAATATTTTAATTAGGAATTTT GATGCTTCTTATGATTTTAAAATTGAAATTATCTATTGATACTACTTTTAACAGAGTCTC TTTGAGAGTTCTGCAAAGACTCAAGTGTGTATACCTGAGTCTATGTATCAGAAAGTAATG GAGATAAATAGAGAAGTAGAAGGTAAGAACAACTTTTTATTTGAAAAGTCTTTTAACCAT ATGTTTGTCTAAACGCATGATGACTGAAATACTCTAATAGCCAAATAAAATTACCCACTA AATACATAACATCGAAAAGAGAGGAGTAAAATGATAAGTTATGTATCTTTTCAGGTGTTG GCAACAGGAATATATAGAGAGTGCAAGAAAAAAACCGAATTATTTGTTTGAATCCAAGAT ACTCTAAGACATGAGGAAAGTCAGGAAATAAGTAAGGGAAAAGGAGTAAAAAGGGAATGA AGACTAAGGAAGGCAGAGAGAGTACAGGGAGTTCATGAAGGAACAAGAAGCAGGTTTATA TAATGGAGGTGGCAAAATAAAATATTTTTTAGAAAAGATAGACCATGCTTAGAAAGATGG CAAGAATATAAAATGATCTTCTGGTCCCAAAACTTGTCAGAAAATTATTGCTAAAGTTTT TTCACTTTTCCTGTCTTTCTCACTACTGGGGAGGCATTAGGAATGGAATTATCTGAGCAT GCAGAATTGTATTTTATTTGCAATAGGTGAGTATTAACAAAAATGCATAGGTGTGCATCT ATATAATTTGTCATATACAGTCAGTATAGACCAATACTTATGAAACATTTAAAAATCAGC TGAATACCTTGGTAATACACAGTATCATTCAGCACAATTGAGTTTCTAAATTTTAATAAG TTCTCAGGCGATGCTGATGTCAGTGGTCCTTGGAGCTCACTTTGAATAGCAAGAGGAGTG CTCATTAGGTTTCTATGTTACAATCAGGCATGACAAATATATATTTTGCTGATGTTAGCT ATTCAAGTGAGATATATTTGAAACTAAGAACATTGCCTTTATATTTTAAGAAAGTGAGTT GTTTTGGTAAAATTGCCATTCCAAAAAAATTTATTATAGACTAATGATACACCAAATCAG ACAAATTGTAGGAACTAAAAAAATACTGAATTTATACTTGAATAATAAGATTGCTTTTTA AAATAAATATTGTGGTGACTTAACAATATAAAAAGTTATTTATGTTTAATACATCTATTG CAATTAATTTTTATATAAATATGTCAATATTGAAAGCTTATAAATTATTTCCATGATGAG TTTTATACATCTTCTTGCATAAGTGGATCAAGAAGCATTCAGATGGATAAACTGGAGGAT ACAGAAATATAGGCATATGATTACACCATATGGTTATGGAAAACAGTGAATATTTATATT TAGTATTATGACCTAAGTATATATCCAAGCTGATCAATTCATAACACTTCACTGATGAGA TGTCAATTCTACATTCAGCTGAACTCTCATCATAACTATGTACCTTTCCAAAGATAGGCC ATATTAAAGAACATGATGAATAGAATAATATAAATGATTTTAATGTGTTTCATTAAGTAT ATGGTGTAGCATTCCATGTTCAGGTTTGACATTTATTTTCTCATATCAACCCTTTTTACA CGTGAAACACAATCTCGCTTTTGAGGTCTTAACTGCATGATCTATGAAACCTATATTTAT ATTTTCTTCAGTGAATTCCTGTCATGTGTGTGTCCTAAACAAACCAAAAGAAAACTTCCC AAATCTAAACTATTCATTCTCAAAGTCAACCAAGAGGACTCAGTTAGATACTATCACTGC ATTCACTCGGTTGGCTTTGTCATATTTACTTATGATTGATGATAAATCTCTTTTGCATTT TAGAGCTTCCTGAGAAGCCATCTGCCTTCAAGGTATTTAGTTTTATGGTTTCATTTTGAA TGACTTATTAACTATGTACTTTGTGAAGTACACATTCTTTATTGATCATTTTTCTTCCAA ACCCATTTAGCCTGCCGTTGAAATGCAAAAGACTGTTCCAAATAAAGCCTTTGAATTGAA GAATGAACAAACATTGAGAGCAGGTAAATTTTTCAATTTAACTATGCAAAGATGAATAGT TCAATATTGGACATTTTGATAGTCTTTCTATCCCCAATGATTTATTTCTTTTAACTTTGA TGAAAAGATTTGATCTAGATAATGCCAATACTGGTATTTATGTTTGAAAACCTGATATTA CAAGAACAGTAATTTTCAATATATTTTTTTTAAAAAAATGTAGCCTTAATCTCAGGTGTT TCTACTTTTGTATCCCGAAACTGTAATGTTTTCTATTTTGAACTTCTGTATTTCTTAAAG ATTCAAGAAGGTGAATTTTGAAACTCTAACTTTTTTAGTTCTTTGAAGCTTGATTCAGAT TCCACGGTTTACTTCGGGGATCAAGTCTTTTACTGATATAACACTTGTGTTTTAATATTA ATTACCTCATTTCCGGTGTTGTCACTTTGGGAATCTTAAGAAACTCAGTAACTCGGATCA GTGAACTCTGTGTGTTTGTGTTTGTGTGTGTGTGTGTCTGCGTGTGTTCCTGTGTGTGTC TGTTTATGTGTGTGGTACCTTTACCTTGTAAAGATGAGGAAAGTAATTAGTCATTTATTT GTGAATATTTGATAAACACATTTTTCCTAAAACTGTAATTCTGAAGCATTTGGCTTTAGA GTCTTTTTACACTAACCTACTTTTTAAAACTATTCTTATGCATGTTTAAATATTTTACAA CGTGTGCATGGTCATATTTAATATGTACAATTTTTTTCAACTTCTAATGTATACATGGTT GTACAGTGTAATGTTCAGCAACATTCTTATTTGATCAGCATTATAATTTTTGGATTCATC CATAAAGGACACAATTAACTGTGTTTTTAAATATTAGGTTGTTTATAAAATTCCATTGTA TGACAGTAGCATAGTTAATTGCACAGTTTTTATGCTGATAAGTAATAAATAAAAATGAAA ACATGCAGATTTCCAAGTCTTTAAAAAGTTAGTTTTATGTGCTAATTTTTTAGTTATTAG AAATTAAAAGTAAAATATTTAAAATATTTCCTTGTGCAATCATACATTCCACTAAGAATT TGAACTGTGCCCCACAGCTTCTTAGAGCTATGGTGTGGCAACACGTAAGATCTCTGAAAC GATCCAGGGTATGCTTCTGAAAATGAGTGAAAATGGTGACTTACCAAAGTATGATCTGAG TTTCTTGGACCCTCTGCATGAAATGTGAACATCAGGGATGCTGAGATCACAGGTTAAATT TACTTTTGAAAACCAGGTAGATTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGA TCGAGACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAG CCGGGTGCGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATG GCGTGAACCCAGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCAGTCTGCAGT CCGGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAC AGGTAGAGAGTTGATAGATGTCGAATGATAAATGTACTGTTAATGATGAAACGGTCTTTT AACTTTTAGTTGTGCACGTTTGCTTTTTTCTTTAACCTGACTCAAATAGTTGTAATTTGT ACTTTTTGCTGATAAAGAAAACTGGAAGTTATTTTTGGTATAAATTCATTTTCTGTCTTA TGTGCCTGAGAACTCCTCAAGTCTTGTGTGGGCCTTGATTTTATCCTATACAACATGTGG GAACGTTAGATTACTTAAGGCAATTATTTTTTCCTATACATTTCTGATGTTTCTCCAAGG TGTCACAAGCTGACTCTGAAGATATTGTTGCATTAGGGAAGCAGTGTGTCGTTGTAATTA AAGCAGTTCTTAATTTATATGCAATAAAAGTTTTTTAAGCTTATCATCCTAAAACATATA CACACCCAAAACACACCCAATACACTGTCATAGCATATTGAAATGTAAAAGGGTTGGACA TATAGTTGACTAATATCAAAAAGTTAATATTCCTAAAAAATTTTATTCATTGATAGATCA TCTTTTTTGAAGAGCTGTGTAATAGAGATTGCTGAGTCAATCAAACTAAGTAACACTAGA AACTAAAAATTTACAAAGAAATGAGAGATGATAGGTAATTAAAGTTTTCTGAATGAACAG CAAATATAGGACATACTGTGTTTTACAGGAGAAGAGGATATGATTGCTTTGTGAAGAAAT AACTCATACAAGTTAGTCAAATTTCTATTTTTCTTCATTCTAATGAAATAATGTTAATTT TCAGACTTTTTAGGTTTCAATTCTGATGGAGTGACTATAGAAGTAGTCACTGTAATCAAC AAAAAGAATATACAGGCTACAGAGGAAAAACTACAGATTCGTGAATGAAAGTAGACTTGT GTATGTTTTTAAAATTTATAGTAGAGAAATGTTCTCATGAATACATCTGTGATTAACCTT TTATAGCTCAGATGTTCCCATCAGAATCCAAACAAAAGGACGATGAAGAAAATTCTTGGG ATTCTGAGGTACTATGTGTTATTGATTTTTTTAAATATTAGTATTGCATGAGATGAAAAC ATAAAATCAGATGCTTAGACTTTATTTTCTCACCTCTGCATATGTCACCCCCAAATTATT TTTTGATATTTTTCAGAATACGCTTAATAGAGAATATATGTGCTAAGTAGATTACCACTT CATGGTGAAATTCTGTGAATTTGTAGGATTAATTTAAGAAGCCGGTGTGGTATAGTGTAA AAAATAAGGCTTAGAATTCACTAGAAATTCACATGGGATCTGAAGTACGTTTGTCTAAAA GCAAAAGAATTACACTGAGTCCAGCTATGGGCAAATACATGATTCTGTCTTATATCTAGA TGTACAAAAGTTCTAACTGGATTCATGGAGAGACACTTTAAACTACAGTATTGCAAAAGT TGGGACCTGAAAAGTTAGTGCCTGGGACTTGAACGTATTGACATATCTTTATTGTTCAGT ATAGATCTGAGGGGACATTTCAGGAGAAAGAAAAGCATGAGGAATAGGAAACCTTGTGGG AATATAATAACAAGAGTATTGGTTGAGCAGTCTATTGAAAAATATAAATTATATTTTCAC AAATAGAACTCCTTGAGTCACTTTATGGCAGTGAAGCTGCAGCAGCATGAGCGTGAAATA ATAGTGATGTGTTTTAAGGTCACAACTGTGGAAAGACATAGAAAGTATCTGACCTCTTAG AAACAAGCAGCTGCTGCCTGATGGTAACAGCAAAGGGTTGAAGTCCATAGAGAGGTAGAT TTTATCTGATTTTTTATTAGACAAAACACTTTAATACCTGTTTGCTTTCATTTAGACATG ACATAATTTTTTTCTTACTGCATTTACATTCTATTCAAGCACTTTTTCTATCATCATAAA TTTTGTCAAAAACATGTTGCTTATTTTAAGCCCCTGTTTACCGAAATAAAGCAGCTTTTT CAGCATTCTGTGCATACACTATATGACAGACTCTAAAAGTTCAAGACAGACATCATTTTT AACGCTAAACAGTTCTATGACCATGAATATTTTAAATGTTTAATGCTGTATGTGTCATGG CAAGTAGAAAATGTATTGTATTTTGTTTGAAATGTCATTTATTTTTGATGAGGACTACAA TATAAGTTAGATATTTTTAAGAGAGATACTTTTTGAAATATGCACGTGTGAATTTTTTCA TGAACATGATTTGTTTTTCCTGCTCAGTAACCAAGTTAATGGCCACATGAATGTAAAGAT AAGCTTGATGTAGAGAGAGTTATGTGAGGTTTTCTTTTATTTTCTTTTATTATTATTATA CTTTAAGTTTTAGGGTACATGTGCACAATGTGCAGTTTAGTTACATATGTATATGTGAGC CATGCTGGTGTGCTCCACCCATTAACTCGTCATTTAGCATTAGTTATATCTCCTAATGCT ATCCCTCCCCGCTCCCCCCACCCCACAACAGTCCCCAGAGTGTGATGTTCCCCTTCCCAT GTCCATGTGTTCTCATTGTTCAATTCCCACCTATGAGTGAGAATATGCGGTGTTTGGTTT TTTGTTGTTGCAATAGTTTACTGAGAATGATGATTTCCAATTTCATCCATGTCCCTACAA AGGACATGAACTCATCATTTTTTATGGCTGCATAGTAATCCATGGTGTATATGTGCCACA TTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTG TGAATAGTGCCACAATAAACATATGTGTGCATGTGTCTTTATAGCAGCATGATTTATAGT CCTTTGGGTATACACCCAGTAATGGGATGACTGGGTCAAATGCTATTTCTAGTTCTAGAT CCCTGAGGAATCGCCACACTGACTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAAC AGTGTAAAAGTGTTCCTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTT TAATGATTGCCATTCTAACTGGTGTGAGATGGTATCTCATTGTGATTTGATTTGCATTTC TCTGATGGCCAATGATGGTGAGCATTTTTTCATGTGTTTTTTGGATGCATAAATGTCTTC TTTTGAGAAGTGTCTGTTCATGTCCTTCACCCACTTTTTGATGGGGTTGTTTTATTCTTG TAAATTTGTTTGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGTCAGAAGAGTAGGTT GCGAAAATGTTCTCCCATTTTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCT GTGCAGAAGCTCTTTAGTTTAATGAGATCCCATTTGTCAATTTTGGCTTTTGTTGCCATT GCTTTTGGTGTTTTAGACATGAAGTCCTTGCCCATGCCTATGTCCTGAATGGTAATGCCT AGGTTTTCTTCTAGGGTTTTTATGGTTTTAAGTCTAACGTTTAAGTCTTTAATCCATCTT GAATTACTTTTTGTATAAGGTGTAAGGAAGGGATCCAGTTTCAGCTTTCTCCATATGGCT AGCCAGTTTTCCCAGCACCATTTATTAAATAGGGAATCCTTTCCCCATTGCTTGTTTTTC TCAGGTTTGTCAAAGATCAGATAGTTCTAGATATGCACCATTATTTCTGAGGGCTGTGTT CTGTTCCATTGATCTATATCTCTGTTTTGGTACCAGTACCACGCTGTTTTGGTCACTGAA GCCTTGTAGTATAGTTTGAAGTCAGGTACTGTGATGCCTACAGCTTTGTTCTTTTGGCTT AGGATTGACTTGGAGATGCAGGCTCTTTTTTGGTTACATATGAACTTTAAAGTAGTTTTT TCCAATTCTGTGAAGAAAGTCATTGGTAGCTTAATGGGGATGGCACTGAATCTATAAATT ACTTGGGCAGTATGGCCATTTTCATGATATTCATTCTTCCTACCCATGAGCATGGAATGT TCTTCCATTTGTTTGTATCCTCTTTTATTTCATTGAGCAGTGGTTTGTAGTTCTCCTTGA AGAGGTCCTTCATGTCCCTTGTAAGTTGGATTCCTAGATATTTCATTCTCTTTGAAGCAA TTGTGAATGGGAGTTCACTCATGATTTGGCTCTCTGTTTGTCTGTTATTGGTGTGTAAGA ATGCTTGTGATTTTTTACATTGATTTTGTATCCTGAGATTTTGCTGAAGCTGCTTATCAG CTTAAGGAGATTTTGGGCTGAGACAATGGGGTTTTCTAGATATACAATCATGTCATCTGC AAATAGGGACAATTTGACTTCCTCTTTTCCTAATTGAATACCCTTTATTTCCTTCTCCTG CCTAAATGCCCTGGCCAGAACTTACAACACTATGTTGATTAGGAGTGCTAAGAGAGGGCA TCCCTGTCTTATGCCAGTTTTCAAAGGGAATGCTTCCAGTTTTTGCCAATTCAGTATGAT ATTGGCTGTGGGTTTGTCATAGATAGCTCTTATTACTTTGAGATACGTCCCATCAATACC TAATTTATTGAGAGTTTTTAGCATGAAGGGTTGTTGAATTTTGTCAAAGGCCTTTTCTGC AACTATTGAGATAATCATGTGGTTTTTGTCTTTGGTTCTGTTTATATGCTGGATTACATT TATTGATTTGCGTATATTGAACCAGCCTTGCATCCCAGGGATGAAGCCCACTTGATCATG GTGGATAAGCTTTTTGATGTGCTGCTGGATTCGGTTTGCCAGTATTTTATTGAGGATTTT TGCATCAATGTTCATCAGGGATATTGGTCTAAAATTCTCTTTTTTTTGTTGTGTCTCTGC CTGGCTTTGGTATCAGGATGATGCTGGCCTCATAAAATGAGTTAGGGAGGATTCCCTCTT TTTCTATTGATTGGAATAGTTTCAGAACGAATGGTACCAGTTCCTCCTTATACCTCTGGA AGAATTCGGCTGTAAATCCATCTGGTCCTGGACTCTTTTTGGTTGGTAAGCTATTGATTA TTGCCACAATTTCAGATCCTGTTATTCGTCTATTCAGAGATTCAACTTATTCCTGGTTTA GTCTTGGGAGGGTGTATGTGTTGAGGAATTTATCCATTTCTTCTAGATTTTCTAGTTTAT TTGTGTAGAGGTGTTTATAGTATTCTCTGATGGCAGTTTGTATTTCTGTGGGATTGATGG TGATTTCTATCAAAATGTTTTGATTTTCTATACGTGTGTACTCTTAAGTCGAATTGTTTG CAAACTAGGAAATTGTGTTTTTAAAAAAGATTCTAGTTAGAAAATTTTGATACTCTTCAT TACTAGGATTTTTTCATTGAAATTATTTATTGATATTACTTTTAACAGAGTCCCTGTGAG ACGGTTTCACAGAAGGATGTGTATTTACCCAAAGCTACACATCAAAAAGAATTCGATACC TTAAGTGGAAAATTAGAAGGTAAGAACCATTTTTTAATTAAAAAGTCATTTGACCAAATA TTTATCTAAACTGATGAGGAAGGATATCCTCTAATAGATGAAGAAAATTACCTCCTTAAT GCAAAGCACAGAAAAAAGAGAAGTGAAACGGTGATAAGTTATACGTCTTATCAGGTGTTG GTAACAGAGTATATTGAGAGTGCTGAAAAGGAACTGAATTATTAGTTTGAATTCAAGGTA TTCCAAGAGCTGAGGAAAATGAGAAAATAAGAAAGGAGAAAGTAGTAAAAGAGGAAATGA AGATCGAGAAAGACAGAGAGTACAGAGAGGACGGGAAGGAACAAGAGGCAGGTTTATATA ATGGAGGATGGTAAAATGAAATGATTCTTTAGGAAAAGATTGGGCATGGTTAGAAATTTG GGAAGAATGTAAAGTGACTTTCTAATGCCAAAACATACCAGAGAATTACAGCAAAAATAT TCTGACTCTTCCTGTCTTTCTCACTGGTGGGAAGCCATTAGGGATGGAAGCAGCTGACCA TGGAGAGCTGTGTTCTATTTGCAATAGTTGAGAATAAGCATATATGCATGGCCACACATG TATATAATTTGTCATATACACTCCGTATAGACCATAAGTTTTCAAACTTTAGAAAACCGT CTGAAAACCTTGTTAACAATTCACACTGTGATTCAGCCGACTAGGGATTCTGCATTTTTA GTAAGTTGTCAGGTGATGCTATTGCTGGTGGTCCTAGGACCTTGCTCTGAGTAGCAAGAT GAGAGACCTTTGTGGGAAAAATGTGGAAGAAGGGCCATTGGGTAGAAGGTCAGGACAGAA AAGGGTCAGGAGAAAGCATTATGGTGCTCCTATTTTTGAGTATGTTTTTAGTTAGGGGAG AAGAAGAAAGGGGCAATGGAATAGAAATTGTAGACGGAAGATACTACTGCTAAACAAAGA AAAAGGAAAGAGTGTGTGTTGAATGGGAAGAAACAAGAGCACAAGTCTAGAGATTACTTT TGCTAAAGAAGAGAGATTATGAGGCAGGAAGCAGGGGACAAGAGAGAAGCCAGCTAGATT ATTTTGGATTTTGTATGAAGGAAAATGGAGTGAATTCACTTCGGAAGCATTTAGAATATT TTCACTGCAGAATGTTAGAGTGTGGGTGCTCCAGAGACTTTTGGAATCATGAGGATTACT AGAATTGGACTAAACCTCAGTGACTCATTAATTTTCTTTATTACTATGAGGCATCAAATA TATATATATATATATATGTATATATTTTGTTGATATTCACAGTTTGAATAAGATATACTA GAATGTAAGAACCTTGGCTTTATTTTTAAGGAAGCAAATTGTGTTGGTAAAATTGCCATT TTATAAAACCTCATTAGCGAATAACATGATATACCAAACCAGACTAATTTTAAAAACCAT AATTCTGAATTCATGACTTGAATACTTAAATTGTTGTTATTCATAGGTATTTTACTGATT TTAACCTAGAAAATTTTGTTAATATTTAATGTCTGTTGCAACTAAATTTATAACAAATAC ATCAATATTGAGGGCTAATTAAGTTTGCTGTTCCTGATGAGGTTTGTACATCTTCCTCCA TGAGTTGATCAAGAAATATTGAGATGGCAAAGCTAGAAATTACAAAAATGTTGGATACTA TTGTAGCATACGGGTATGAAAATCAATGAATATTTATATTTAGTATTATGCTCCAAGTAT ATATCCAAGCTGATCAATTCATAACACTTTCACTGATGAGATGTCAAATCTACATTCAGC TGAACTCTCATCCGAACTGTGTACTTTCTCAATGACAGGACATATTAAAGAACATGATAA ATATTTGTAATGTAATGATACAAATTATTATAATGTGTTGCATTAAAGACACATGGTGTA GCATTCTATGTTCAGCTTTTGCATTTATTTTCTCAGTGTCATGATTTGCTCCTCTGATTC AAGATCACTTATCTCCTCATCACTCAGCGTATACATATTGGCATTAACATTTTTTGCAAA AATCATATATAAATGGGTGTACAATGTTCTTGTCATTCTACAGCAACTTTTTATTTTTTG TTCAGCGATTAGCTTGTTTTTCATTTATTTAAAGATTTCAGGCCAGGCGTGGTGACTCAC GCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCCA GACCATCCTGGCTAACACGGTGAAACCCCATCTCTAATAAAAATACAAAAAATTAGCCGG GCGTGGCGGTGGGTGCCTGTAGTCCCAGCCACTCAGGAGGTTGAGGCAGGAGAATGGCCT GAACCCGGGAGGTGGAGCTTGTATTCTGCCGAGATCTCAACACTGCACTCCAGCCTGGGC GACAGGGCGAGACACCGACAAAAGAAAAAAAAAAAATCATAGTGTGCATTTTTACTTTCC ACCACATTTAATTAGACTCTCTTCATGGTGACTAAAAAGCATCATAATAATTATAGATGT CAACAAGCCTTTGTTTAAGTGTATGTCCTACTTCACGCTATATTAGAAATTAAAAGTGAA GTAATTAAAATGCAAGGATGCACAGCCATACATTTCAATAGCCATTACAAATGTGGCTCA CTAATCTTTAGAGCCATGCCATGTGACCTGTCCTGATTTTAAAAAACTCCAGTGTACCCC TTTATAAAAAAAAGTAATTTAAAAAAATAACGAAGGTAGTATTTCCCTGCTTGCTTCCTC TGCATGGATTTTGAACTTCAGGGATAATCAGATCACATTTTAGAACCAGAGTTTTCAACC ATAAATAGGATTCCTAAATGCCAAGTGATAAACGGTTCGTTGATGATGAGATAGCTCTGA ATGTTTCATCTCTGCGTGTTTTGCTTTTTTATCTTGTCTTAGAAAGGTCAAAGCCAGCTA TTTTCTTCATAAAGGAAAATATTTTGGTTACATACTCATTTCCTATCTCATGACACTCTG CTTTCTTTGCACTTAGTGAGGATGTACATTTATCATATTTTTACCTAAAACAAGCAGATG AATTAATGGTATCATTTCCTATATATGAATTTCTGAGGTTTCTTCAGTGCTTCAGAAGTA AAGTTTAAAGATATTAATGAATCGAGGACGATCTTCTCATCGTAATTAAAGCGGGTTTTT ATTTAAAGTGTATTGAATACAATTTTAAGCACTTTTTTTCTAAAACACATACCTGCAACA CGGTCATGCATATTTAGCCTTAAATCGCTTGGACATAAATTGTGTGTGTTTTAGAGAGTT TATGTCCCCTGAAGTGTCTTCATTACTGATCAATCAACTCCAAAGGAAACAACATATATA CTTGATATGTCTAAATATATTAAAGTGTGTCTTACTGAAAAATAACAAAGTAGAGAAAAA TGAGAGATTAAGCATGTTGTATTCATATTATTTGATGAAAGGAGATATATTTCTATTTCA AAGAAATGTCTGTTTTTTCTTGAAGCTAAGCTTTCTATAAAAGCTTTTTCATAACAGTGG CTTAACAACTCACATGGTATAACAAATAGAATTAGTTTTAGCAACAAAGCAATTGTAGAA TTCATTCCTTGAACAATAAAACTGTTATTTTCAATAACCATTACTCTAACATTGAAATAT GCAGGTTAATGATATGTAAAAAGTCTCTGGAAATTGACATCTAGTTTTTGATACTTTCAT ATCAGGTGTTTTTTCTTTTGTTGAGACAGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCA GGGGCATGATCTTGACTCACTGCCACCTGGGCCTCCTGGGTTCAAGTGATTCTCACAGCT CCGGCTCCCAAGTAGCTGCGGTTACAGGCATGTGCCACCATACCTGGATGATTTTTGTAT TTTTTGTGGAGACAGGGTTTCGCTATTTTGGCCAGGCTGCTTTGGAACTCCTGGCCTTGA GAGATCCGCCCTCTTCAGGCGTCCAAGGTTCTGGAGTTACAGGCATGAGCCATGCCACCT GGACTGTATTAGTTTGTGGATGGGTGTGCTTTGACTTTTCTGTATAAGTGGATCAGGAAA TTTTGAGAGGACTAAACCAGAGAACCCCATAAATGTAAAAATACTCCTATTTCACAGAGG TTCAAAAATAAATATATTTATAAACTTTTATTCTATAAGTAGATATTTATGCTGATAAAT TTAGAACATCCTCTGCAATGATAAGTAAATTGTACCTTTGAATTCTCATCGCAGCTTTGC AATTCTTAAATTACAGGACAAATTGAAGAACATAATAGCTACTTGCAGTATATTGACATA AGAGACTCTGATGTGTTTCCTTAACAATATGCCATAGCATTCTTCCGTTACCTAGGACTT ATTTTTTTTTTTTTTGGCGGTGGGTCATGACTTGGTCATCTTAGTAAATTCAACTTCTTT CCCTATACGGCAGATTAATCTTACTGGTATTAGGATTTTTCTAATTTAGTTATTGTCAGT TGAAATATATTTTGATTGTTAAAATCTCCATAGCAAGTTTGATGAAGGTTATTTTTTAAG TTTTCTTAAGTATATTTCTGTCCCGTTGGCATGTTAACAAATACAAAAGCCCAAAAGACC CCAAAACCTAGTGTAATCCCTTTTCAATCCAAGCATGAGGATTCATCTTCATATTCACAT TGTACGAATGCTTGGTAGGCTTTGTCAGGCTTGCATATAATCAATTATATATGTCCCTTT ACGTTTAGAGTCTCCTGTTAAAGATGGTCTTCTGAAGGTAATAACTTTTATATTGCTATC TTGAATACTAACTACATATTTTAGGAAGCATATATTATGTATTAATTTTTGTGTTTCCAA ACCCATTTAGCCTACCTGTGGAAGGAAAGTTTCTCTTCCAAATAAAGCCTTAGAATTAAA GGACAGAGAAACATTCAAAGCAGGTAAATTTTGTAATTTAACTTTTAATCTGTAATTAAG AATATTAAACTATTTGAAATGCCGAGAGGCTTTTATTCCCAATGTTGTTTTCTTTTGAAA ATTTGGTGGGAAAATTTGAAACAAATAATGCCAATGTTAGCATTTATGTTTGAGAAAATG CCATTTACAAGCATAAGATTTAGAGATTAACAAAAAATTCAGCTTTGCCTCATGTGGATA TCTGTCCAGCAGCCTGCAATACAATGGGGCCTTGTCTTTGTTCCCAGGTGGATCGGCAGG TTGAGACATAATAGACACAGACAAGATAGTGAAAGCTGGGTCCAGGGGAATCACCACCTT GTCGTCCCGTAGTGCCAACAATTCACTGGATATACCCACATTTATTATTAAGTTTAGTGA GGGTGGGGGTGGGTTAATGAGGGATTTAGGGTCATTTGATTATGAGGTGAGATGGTCCCA TGTGGATGAAGTAATTCTGTAACTAACATCTGTATGCAGAAATACAGTATACAGGGATAA GAATTTACAATATAGTGTGTGCATCGGTAATTTCTAACAAAGCCTTAAAACAGAAATGCA GACTTTCCATAACCTATGATTAGCAAGATATTAATCAGCAGTAACAGTTGCAGCAAAAGC TGGTTACAAACAATCCATAGAAACAGGATGTGAAGCTAGACAACTGGGTAGACCAGAAAT TCTCAGAAGGGAGTATGCCTTAACCCTAAAGAGGCCTAGAAGAGCCGTGGCAAGATGAGG GCATTCATAGCACTATCTTATCCATATGGACAGGTACCCCCCCATGCGTCTGTTTATAGG CTCTCCACAAGGGTAGGATTCCATTCCCAGAGCTATGAACATATGCCTTTCTGGGACAGG AATCTTGGTGACGCGAAACCTCCCTGACTGCACATCCATTCACAGGTTCTCTGCAGGGGG AAGCACATCACGTGCTGTTGGCTCATTCTGGCAGTCCAACCTGGCATTGTCTTTACACAA TCCTGCATGCAGTTTTGTATTTACAATAACCAGGAGCATTGCATCTTTTATTCCATAGCA ATAGTTTCAGGGGGTCTCCCTACAGTTGGCATGTTAACAAATACAATAACCCAAAGGACC CCAAAACCTAGTGTAATCCCTTTCCAATCCAAGCATGAGGATTCATCTTCATATTCACAC TGTATGAACGTTTGGTAGGCTTTGTCAGGCTTGCATATAATCAATTATAAATGTCCCTTT TCTTTTAGAGTCTCCTGATAAAGATGGTCTTCTGAAGGTAATAGCTTTTATGTCTCTATC TTGAATATTAACTACATATTTTTGAAGTGTACATTATATATTAATTTTTGTGTTTCCGAA CCCATTTAGCCTACCTGTGGAAGGAAAGTTTCTCTTCCAAATAAAGCCTTAGAATTAAAG GACAGAGAAACACTCAAAGCAGGTACATTTTGTAATTTAAATTTTAATCTGGAATTAAGA ATATTAAACTATTTGAAATGCCAAGAGCCTTTTATTCCCAATGTTGTTTTCTTTTGAAAA TTTGATGGGAAAATTTGATACAAATAATGCCAATGTTAGTATTTATGTTTGAGAAAATGT CATTTAGAAGCATAAGATTTAGAGATAAAAAAATTCAGCTTTGCCTCATGTGGATATCTG TCCAGCAGCCTGCAATGCAACGGGGCCTTGTCTTTGTTCCCAGGTGGATCAGCAGGTTGA GAAATAATAGACACAGACAAGATAGTGAAAGCTGTGTCCAGGAGAATCACCGCCTTGTCG TCCCGTGGTGCCAACAATTCACTGGATATACCCGCATTTGTTATTAAGTTTAGTGAGGGT GGGGGTGGGTTAATGAGGGATTTAGGGTCATTTGATTATGAGGTGAGATGGTCACATGGG GATGAAGTAATTCTTTAACTAACATCTGTATGCAGAAATACAGTACACAGGGATAAGAAT TTACAATATAGTGTGTGCATCGGTAATTTCTAACAGAGCCTTAAAAAAGAAACACAGTCT TTCCATAACCTATGATTAGCAAGATATTAATCAGTAGTAACAGTTGCAGCAAAAGCTGGT TACAAACAATCCATAGAAACAGGATGTGAAGCTACACAACCGGTTAGACCAGAAATTCTC AGAAGGGAGTATGCCTTAACCCTAAAGAGGCTAGAAGAGCCGTGGCAAGATGAGGGCGTT CATAGCACTATCTTATCCATATGGACAGGCACCCCCCTCCGTGCGTCCATTTATAGGCTC TCCACAAGGGTAGCATTCCATTCCCAGAGCTATGAACATATGCCTTTCTGGGATAGGAAC CTTGGTGATGTGAAACCTCCCTGACGGCACATCCATTCACAGGCTCTCTGCAGGGGGTAG CACATCACCCACTGTTGGCTCATTCTGGCAGTCCAACCTGGCATTGTCTTTACACAATCC TGCATGCAATTTTGTATTTACAATAATCAGGAGCATTGCATCTTTCATTCCATAGCAACA GTTTCAGGGGGTCTCCCTACAGTTGGCATGTTAACAAATACAATAACCCAAAAGACCCCA AAACCTAGTGTAATCCCTTTTCAATCCAAGCATCATGAGGATTCGTCTTCATATTCACAC TCTATGAACGTTTGGTAGGCTTTGTCAAGCTTGCATATAATCAATTATATATGTCCCTTT TCTTTTAGAGTCTCCTGATAATGATGGTCTTCTGAAGGTAATAACTTTTATATTTTTATC TTGAATATTACCTACATATTTTATGAAGTATACATTATATGTTAATTTTTGTGTTTCCAA ACCCATTTAGCCTACCTGTGGAAGGAAAGTTTCTCTTCCAAATAAAGCTTTAGAATTGAA GGACAGAGAAACATTCAAAGCAGGTAAATTTTGCAATTTTAATTTTACTCTGGAATTAAG AATATTAAACTATTTGAAATGCTGAGCACCTTTTTATTCCCAATGTTGTTTTCTTTTCAA AATTGGATGGGAAAATTTGATAAAATAATGGCAACATTAGTATTCATGTTTGAGAAAATG CCATTTACAAGCATAAGAAATAGGGATTTAGAAAAAAATTCTGCTTTACTTCATGTGGTT CTTCTTTAATATCCCGATAGTATAAAGTTTCCAATTTGCAATTTCTGTACGTGCTCGGTT TTAAGGCAGGTGAATTTTGAAACTGTGAAATATTTTCAGTGTTTCAAATGCTGACTGGAA TTCTGATCTTTACTTTGAGGAAAGTTTCACTTGCTGAGGTGACAGTTGTGAGCATTGTCA CTCTGAGAATCTAAAGAAAATCAGTTTCTTGTTTTTCTGATTAGGTGACTGAGTGTGTGT GTGTGTGTGTGACATATAATTTTTAAAAATCATTACTTGATGATTCTTTGCTAGATACAC TGTTTCAGAAGTGTGACTCTAAAGCTTTTGGCCTTGGTGTCTTTTTATGCTACTGTAATT AATTGCCTAGAGGTACAAAACAGCCTGAATTAATTTTTGTTGTCATTCCCATGCATGTTT AAATCATGTTACAACAGGCTGTGCACGGTGGCACATGCCTGTAATCCTGGCAATTTAGGA GACCAAGGTGGGCAGATTACTTAAGGTCAGGAGTCGCAGACGAGCCTGGTCAACACAGTG AAACCCCATCGCTACTAAAAATAACAAACAATAGCCGGTTGTGGTGGTGGGTGCCCGTAA TCTCAGCTATTCTGGAGGCTGAGGCAGGAGAATTGCTTGAACCCATGAGGCAGAAGTTGC AGTGAGCCAAGCTTGTGCCACTTTAGCCTGAGTGACAGAGTGAGACTCCATCTCAAAAAG CAAACAACCATAAATTCACAACATATGTGTGTGGTTCTGACTATGTGTAGAATTTGTTTT GACGTCTTAAATTTTCTTTTTTTTTTAAATTTTGATATGGCGTCTCGCTGTCTCGCCCAT CTCGTTGTCTTGCCCAGGCTGGAGAGCAGTGGTGTGATCTTGGCGCACTGCAAGCTCCAC CTCCCAGGTTCACGCCATTCTCCTGCCTGGGCCTCCCAAGTAGCTGGGAATCCAGACGCC TACCACAACGCCTGGCTCATTCTTTGTATTTTTAGTAGAAACGGGGTTTCACCATGTTAG CCAGGATGATCTCGACCTGCTGACCTTGTAATCCACCCACCTCGGCCTCCTAAAGTGCTG GGATTAGAGGCGTGAGCCACCGCGCCCGGCCCAGAGTCTTTTTACACTAGTACCATTTAT TGCCTAGAAGTAACCAATATTCTAAACTACTTTTTAAAAGTATTCTTATGCATGTTTAAA CATTTTCCAACATGTGTACGTGGTCATATTTAATACATAAAATTTTTTTCAACTTCTAAT GCATAGGTGGTTGTACAGTGTAATTTTTGACAACATTCTGTTTTGATCAGCATTATAATT TTTAGAGACGTCCATAAAGGACACAATTAACTGTCTTTTTAAATGTCAGATTGTTTATAA AATTCCATTAAGTACACAATTATTATGCTGATAAATAAAAATGAAAACATGAAAATTTCA GAGTCTTTAAGTTAGTTATATCTACTGACTTTTTAGTTGTGAGAAATTAAAACTAAAATA TTTAAAGTATTTCCTTGTGCAATCATACATTCCACTAACAATTCCAACTGCGACCCACAG ATTATTAGAGCTATGCTACTGCAACACATTAGATCTCTGAAACGATCCAGGGTACACTTC TAAACATGAGTGAAAATGGTGGCATACCAAAGTATGATTTTAGTTTCTTGGTCCCTCTGC ATGAAATGTGAACTTTAGGGATGCTGAGATTACATGTTAAATTTACTTTTAAAAACCAGA TACACAGTTGATGGATGTCAAATGATAAACGTACCTTTAACGATGATACAGTCTTTTAGG CTTTAGTCGTGCATGTTTGCTTTTTTCTTTAACCTGATTCAAAGAGTTGTAATGTGTACT TTTGGTTGATAAACAAAGCTGAACGTTATTTTTGGTATAAATTCATTTTCTGTCTCATTG GCCTGAGAGCTCCTCAAGTCTTGTGTGGGCCTTGATTTTATCCTATAACATGTGGGGATG TGAGATTACTTAGGGCAATTATTTTTTCCTATACATTTCTGATGTTTCTCTTAGTTGTCA CAAGCTGACTCTGAAGACATTGTTGAGTTAGGGGAGAACTATGTCATTGTAATTAAAGCA GTTCTTAATTTATATGCAATAAAAGTTTTTTAAGCTTATCTTCCTAAAACATATAGACAC CCAAAACACACCCAATATACTGTCATGGCATATTGAAATGTAAAAGTGTTGGACATATAG TTTACTAACATCAGAAAGTTAATATCCCTAAAAAATCTTGTTCGTTGATAAATCATCTTT TTTGAAGAACTGTGTAATAGAGATTGCAGAGTCAATCAAACTAAGTAATACTAGAAAATA AAAATTTACAAAGAAGTGAGAGATGATAGGTAATTAAAGTTTTCTGAATGAACAGCAAGT ATAGGACACACTGTGTTTCACGGGAGAAGAGGATGTAACTGCTTTGTGAAGAAATAACTC TACGAGTTAGTCAAATTTCTATTTTTCTGCATTCTAACGAATGATATAATGTTAATTTTC CGTTTTTTTAGATTTCATTTCTAACGGATTGACTATAGAAGTAGTGATTGTAATCAACAA AAAGAATATACGGGCTACAGAGGAAAAACCGCAGATTCGTGAATGAAAGTAGATTTATAT ATGTTTTTAAAGTTTATAGTAGAGAAATGTTCTCATGAATGTATCTGTGATTAACCTTTT ATAGCTCAGATGTTCCCATCAGAATCCAAACAAAAGGATGATGAAGAAAATTCTTGGGAT TTTGAGGTACTGTGTATTATTAATTTTCTTTAATACTAGTATTGCATGATACAAAAACAT AAAAGCAGAGGCTTAGACTTTATTTTCTCACCTCTGCATATGTCACTCCCAAATTATTTT TGATATTTTTCAGAATACGCTTAATAGAGGATCTATGTGCTAAGTAGATGACTGCTTCGT AGTGAAATTCTGCTAATTTTCAGGCTTAATTTAAGAAGCCGGTGTGGTATAGTGTAAAAA ATAAGGCTTAGAAGTCACTAGAAATTCACATGGGATCTGAAGCAAGTTTGTCTAAAAGCA AAAGAATTACACTGAGTCCAGCTGTGGGCAAATTTATGATTCTGTGGTGTATCTAGATGT GCAAAAGTTCTAACTGGATTCGTAGAGAGACAGTTTAAACTGCAGTATTGTAAAAGTTGG GACCTGAAAAGTTAATGCCTGGGACTTGAATGTATTGACATTTCTGTATTGTTCAGTATA GATCTGAGGGAACATTTCAGGAGAAAGAGGAGCATGAGGACTAGGAAACCTTGTGGGACT ACAGTAACAAGAGTATTGGTTGAGTAATCTTTTGAAAAATATAAATTATTTTCACAAGTA GAACTCCTCGAGTCCCTTTGTGGCAGGCAGTCAAGCTGCAGCAGCATGAGTGTGAAATAA TAGTGATGTATTTTAAGGTCACAACTGTGGAAAGACATAGAAAATATCTGACCTCTTAGA AACAAGCAGCTGCTGCCTGGTGGTAAGAGCAAAGGGTGGAAGTCAGTAGACAAGTAGATT TTATCTGATTTGTCGTCAGACAAAAAGACTTTAATATTTGTTGGCTTTCATTTAGACATG ACATAATTTCTTTTCTTACTGCATTTACATTCTCTTCAAGCACTTTTTCTATCAGCATAA ATTTTGTCAAAAACATGTTGCTTGTTTTAAGCCCCTGTTTACCAAAATAAAGCAACTTTT TAAACATTCCGTGCATGCATTATATGACAGACTCTAAAAGTTCTCTTCACGGCATGCATC ATTTTTAACACTAAACAATCTATGATCATGAATATTTTAAATGTTTAATGCAGTACGTGT TATGGCTAGTAGCAAGTGTATTGTATTTTGTTTGAAATGGCGTATTTACTTTTAATGAGG ACTACAACACAAGTTAGATATTTTTAAGAGAGTTACTTTCTGAAATATGCACGAGTGAAT TCTTTCGTGAGTGTGATTTGTTTTTCCTGCTCAGTAACCAAGTTAATAGCCTCATGAACG TAAAGGTAAGTTGATGTGGAGAGTGTTATGTGAGGTTTTCTATCAGAATGTTTTGGGTTT CAACACATGTCTGCTCTTAAGTCGAATTCCTTGTAAAGTAGGAAACTGTGTTTTTAGAAA AGATTTTAATTAGGAACTTTTGATACTCCTCATTATTGGGATTTCTCCATTGAAATTATT TATTGATATTACTTTTAACAGAGTTTCCTTGAGACTCTCTTACAGAATGATGTGTGTTTA CCCAAGGCTACACATCAAAAAGAATTCGATACCTTAAGTGGAAAATTAGAAGGTAAGAAC CATATTTTATTTAAAAAGTCATTTGACCAAATGTTTCTCTGAACTGATGAGGAGGGATAT CCCCTAATAGCTGAAGAAAATTACCTCCTGAATGCAAAGCATGGAAAAAAAGAGAAGTGA AATGGTGATAAGTTATACGTCTTATCATGTGTTGGCAGCAGACTACATAGAGAGTGCTGG AAAGGAACTGAATTATTAGTTTGAATTCAAGGTATTCCAAGAGCTGAGGAAAATGAGAAA ATAAGAAAGGAGAAAGTAGTAAAAGAGGAAATGAAGATCGAGAAAGACAGAGAGTACAGA GAGGACGGGAAGGAACAAGAGGCAGGTTTATATAATGGAGGATGGTAAAATGAAATGATT CTTTAGGAAAAGATCGGGTATGGTTAGAAATTTGGGAAGAATATAAAGTGACTTTCCAGT GCCAAAACATACCAGAGAATTACAGCAAAAATATTCTGACTCTTCCTGTCTTTCTCACTG GTGGGAAGCCATTAGGGATGGAAGCAGCTGACCATGGAGAGCTGTGTTCTATTTGCAATA GTTGAGAATAAGCATATATGCACGGCCACACATGTATATAATTTGTCATATACACTCCGT ATAGACCGTAAGTTTTCAAACTTTAGAAAACCGTCTGAAAACCTTGTTAACAATTCACAC TGTGATTCAGCCGACTAGGGATTCTGCATTTTTAGTAAGTTGTCAGGCGATGCTGATGCT GGTGGTCGTTGGACCTTGCTCTGAGTAGCAAGATGAGAGACCTTTGTGGGAAAAAATGTG GAAGAAGGGCCATTGGGTAGAAGGTCAGGACAGAAAAGGGTCAGGAGAAAGCATTATGGT GCTCCTATTTTTGAGTATGTTTTTAGTTAGGGGAGAAGAAGAAAGGGGCAATGGAATAGA AATTGTAGATGGAAGATACTACTTCTATACAAAGAAAAAGGAAAGAGTGTGTGTTGAATG GGAAGAATCAAGAACACAAGTCTAGTGATTACTTTTGCTAAAGAAGAGAGATTATGAGGC AGGAAGCAGGGGACAAGAGAGAAGCCAGCTAGATTATTTTGGATTTTGTATGAAGGAAAA TGGAGTGAACTCACTTCGGAAGCATTTAGAATATTTTTACTGCAGAATGTTAGAGTGTGG GTGCTCCAGAGACTTTTGGAATCATGAGGATTACTAGAATAGGACTAAACCTCAGTGACT CATTAATTTTCTTTATTACTATGAGGCATCAAATATATATATATATGTATATATTTTGTT GATATTCACAATTTGAATAAGACATACTAGAATGTAAGAACCTTGGCTTTATTTTTAAGG AAGCAAATTGTGTTGGTAAAATTGCCATTTTATAAAACCTCATTAGCGAATAACATGATA TACCAAACCAGACTAATTTTAAAAACCATAATTCTGAATTTATGACTTGAATACTTAAAT TGTTGTTATTCATAGGTATTTTACTGATTTTAACCTAGAAAATTTTGTTAATATTTAATA AGTCTGTTGAAACTAAATTTATAACAAATACATCAATATTGAGGGCCAATTAAATTTGCT GTTCCTGATGAGGTTTGTACATCTTCCTCCATCAGTGGATCAAGAAATATTGAGATGGCA AAGCTAGAAATTACAAAAATGTTGGATACTATTGTAGCATACGGGTATGAAAATCAATGA ATATTTATATTTAGTATTATGCTCCAAGTATATATCCAAGCTGATCAATTCATAACACTT TCACTGATGAGATGTCAAATCTACATTCAGCTGAACTCTCATCCGAACTGTGTACTTTCT CAATGACAGGACATATTAAAGAACATGATGAATATTTGTAATGATATAAATTATTATAAT GTGTTGCATTAAAGACACATGGTGTAGCATTCTACGTTCAGCTTTTGCATTTATTTTCTC AGTGTCATGATTTGCTCCTCTGATTCAAGATCACTTATCTCCTCATCACTCAGCGTATAC ATATTGGCATTAACATTTTTTGCAAAAATCATATATAAATGGGTGTACAATGTTCTTGTC ATTCTACAGCAACTTTTTATTTTTTGTTCAGCGATTAGCTTGTTTTTCATTTATTTAAAG ATTTCAGGCCAGGCGTGGTGACTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCG GGCAGATCACGAGGTCAGGAGATCCAGACCATCCTGGCTAACACGGTGAAACCCCATCTC TAATAAAAATACAAAAAATTAGCCGGGCGTGGCGGTGGGTGCCTGTAGTCCCAGCCACTC AGGAGGTTGAGGCAGGAGAATGGCCTGAACCCGGGAGGTGGAGCTTACAGTCAGCCCAGA TCTCAACACTGCCCTCCAGCCTGGGTGACAGGGCGAGACACCGCCAAAAAAAAAAAAGAA AAAAAAAATCATAGTGTGCATTTTTACTTTCCACCACATTTAATTAGACTCTCTTCATGG TGACTAAAAAGCATCATAATAATTACAGATGTCAGCAAGCCTTTGTTTAAGTGTATGTCC TACTTCACGCTATATTAGAAATTAAAAGTGAAGTAATTAAAATGCAAGGATGCACAGCCA TACATTTCAATAGCCATTACAAATGTGGCTCACTAATCTTTAGAGCCATGCCATGTGACC CGTCCTGATTTTAAAATCTCCAGTGTACCCCTTTATAAAAAGAAAGTAATTTAAAAAAAT AACGAAGGTAGTATTTCCCTGCTTGCTTCCTCTGCATGGATTTTGAACTTCAGGGATAAT CAGATCACATTTTAGAACCAGAGTTTTCAACCATAAATAGGATTCCTAAATGCCAAGTGA TAAACGGTTCGTTGATGATGAGATAGCTCTGAATGTTTCATCTCTGCGTGTTTTGCTTTT TTATCTTGTCTTAGAAAGGTCAAAGCCAGCTATTTTCTTCATAAAGGAAAATATTTTGGT TACATACTCATTTCCTATCTCATGACACTCTGCTTTCTTTGCACTTAGTGAGGATGTACA TTTATCATATTTTTACCTAAAACAAGCAGATGAATTAATGGTATCATTTCCTATATACGA ATTTCTGAGGTTTCTTCAGTGCTTCAGAAGTAAAGTTTAAAGATATTAATGAATCGAGAA CGACCTTCTCATCGTAATTAAAGCGGGTTTTTATTTAAAGTGTATTGAATACAATTTTAA GCACTTTTTTTCTAAAACACATACCTGCAACACGGTCATGCATATTTAGCCTTAAAATGC TTGCACATAAATTTTGTGTGTTTTAGAGAGTTTATGTCCCCTGAAGTGTCTTCATTACTG ATCAATCAACTCCAAAGGAAACAACATATATACTTGACATGTCTAAATATATTAAAGTGT GTCTTACTGAAAAATAACAAAGTAGAGAAAAATGAGAGATTAAGCATGTTGTATTCATAT TATTTGAGGAAATGAGATATATTTCTATGTCAAAGAAATGTCTGTTTTTTTCTTGAAGCT AAGCTTTCTATAAAAGCTTTTTCATAACAGTGGTTTAACAACTCGCATGGTATAACAAAT AGAATTAGTTTTAGCAAAGCAAAGCAATTGTAGAATTCATTCCTTGAACAATAAAACTGT TATTTTCAATAACCATTATTCTAACATTGAAATATGCAGGTTAATGATATGTAAAAAGTC TCTGGAAATTGACATCTAATTTTTGATACTTTCATATCAGGTGTTTTTTCTTTTGTTGAG ACAGAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGGGGCATGATCTTGACTCACTGCCA CCTGGGCCTCCTGGGTTCAAGTGATTCTCACAGCTCCGGCTCCCAAGTAGCTGCGGTTAC AGGCATGTGCCACCATACCTGGATGATTTTTGTATTTTTTGTGGAGACAGGGTTTCGCTA TTTTGGCCAGGCTGCTTTGGAACTCCTGGCCTTGAGAGATCCACCCTCTTCGGGTTTCCA AGGTTCTGGAGATACAGGCATGAGCCACGGCACCTGGACTGTATTAGTTTGTGGATGGGT GTGCTTTGACTTTTCTGTATAAGTGGATCAGGAAATTTTGAGAGGACTAAACCAGAGAAC CCCATAAATGTAAAAATACTCCTATATCACAGAGTATCAAAAATAAATATATTCATAACT TTTATTCTATAAGTAGATATTTATGCTGATAAATTTAGAACATCCTCTGCAATGATAAGT AAATTGTACCTTTGAATTCTCATCGGAGCTTTGCAATTCTTAAATTACAGGACAAATTGA AGAACATAATAGCTACTTGCAGTATATTGACATAAGAGATTCTGATGTGTTTCCTTAACA ATATGTCATAGCATTCTACCATTACCTAGGACTTATTTTTTTTTTGGCGGGGGGTCATGA CTTGGTCATCTTAATAAATTCAACTTCTTTCCCTATACGGCAGATTAATCTTACTGGTAT TAGGATTTTTCTACTTTAGTTATTGTCAGTTGAAATATATTTTGACTGTTGAAATCTTCA TAGCACGTTTGATGAAATTTATTTTTTAAATTTTCTTAAGTATATTTCTGTCCCATTGGC ATGTTAACAAATACAAAAACCCAAAAGACCCCAAAACCTAGTGTAATCCCTTTTCAATCC AAGCATGAGGACTCATCTTCATATTCACATTGTACGAATGCTTGGTAGGCTTTGTCAGGC TTGCATATAATCAATTATATATGTCCCTTTTCTTTTAGAGTCTCCTGATAAAGATGGTCT TCTGAAGGTAATTACTTTTATATTTCTATGTTGAATATTAACTACATATTTTTGAAGTAT ACATTATATATTAATTTTTGTGTTTCCAAACCCATTTAGCCTACCTGTGGAAGGAAAGTT TCTCTTCCAAATAAAGCCTTAGAATTAAAGGACAGAGAAACACTCAAAGCAGGTAAATTT TGTAATTTAAATTTTAATCTGGAATTAAGAATATTAAACTATTTGAAATGCCAAGAGCCT TTTATTCCCAATGTTGTTTTCTTTAGAAAATTTGGTGGGAAAATTTGATACAAATAATGC AAATGTTAGTATTTATGTTTGAGAAAATGTCATTTAGAAGCATAAGATTTAGAGATAAAA AAAATTCAGCTTTGCCTCATGTGGATATCTGTCCAGCAGCCTGCAATGCAATGGGGCCTT GTCTTTGTTCCCAGGTGGATCGGCAGGTTGAGAAAGAATAGACACAGACAAGATAGTGAA AGCTGGGTCCAGGGGAATCACAGCCTTGTGTTCCCGTGGTGCCAACAATTCACTAGATAT ACCCGCATTTACTATTAAGTTTAGTGAGGGTGGGGGTGGGTTAATGAGGGATTTAGGGTC ATTTGATTTTGAGGTGAGATGGTCACATGGGGATGAAGTAATTCTTTAACTAACATCTGT ATGCAGAAATACAGTACACAGGGATAAGAATTTACAATATAGTGTGTGCATCGGTAATTT CTAACAGAGCCTTAAAAAAGAAACACAGTCTTTCCATAACCTATGATTAGCAAGATATTA ATCAGCAGTAACAGTTGCAGCAAAAGCTGGTTAGAAACAATCCATAGAAACACAATGTGA AGCTAGACAACTGGTTAGACCAGAAATTCTCAGAAGGGAGTATGCCTTAACCCTAAAGAG GCCTAGAAGAGCCATGGCGAGATGAGGGCGTTCATAGCACTATCTTATCCATATGGACAG GCACCCCCCATGCATCTGTTTATAGGCTCTCCACAAGGGTAGCATTCCATTCCCAGAGCT ATGAACATATGCCTTTCTGGGATAGGAATCTTGGTGATGCAAAACCTCCCTGACTGCACG TCCATTCACAGGCTCTCTGCAGGGGGAAACACATCACGCGCTGTTGGCTCATTCTGGCAG TCCAACCTGGCATTGTCTTTACACAATCCTGCATGCAATTTTGTTTTACAATAATCAGGA GCATTGCATCTTTCATTCCATAGCAATAGTTTCAGGGAGTCTTCCTACAGTTGACATGTT AACAAATACAATAACCCAAAAGACCCCAAAACCTAGTGTAATCCCTTTTCAATCCAAGCA TGAGGATTCATCTTCATATTCACACTCTATGAACATTTGGTAGGCTTTGTCAGGCTTGCA TATAATCAATTATATATGTCCCTTTTCTTTTAGAGTCTCCTGATAAAGATGGTCTTCTGA AGGTAATAACTTTTATATTTTTATCTTGAATATTACCTACATATTTTATGAAGTATACAT TATCTATTAATTTTTGTGTTTCCAAACCCATTTAGCCTACCTGTGTAAGGAAAGTTTCTC TTCCAAATAAAGCCTTAGAATTAAAGGACAGAGAAACATTAAAAGCAGGTAAACTTTGTA ATTTAAATTTTACTCTGGAATTAAGAATATTAAACTATTTGAAATGCTGAGAGCCTTTTA TTCCCAAAGTTGTTTTCTTTTGAAAATTTGATGGGAAAATTTGATACAAATAATGCAAAT GTTAGTATTTATGTTTGAGAAAATGCCATTTAGAAGCATAAGAATTAGGGATTTAGAAAA AAATTCTGCTTTACGTCATGTGGTTCTTCTTTAATATCCCGATAGTGTAAAGTTTCCAAT TTGCAATTTCTGTACGTGCTCAGTTTTACGGCAGGTGAATTTTGAAACTGTGAAATATTT TCAGTGGTTCAAATGCTGACTGGAATTCTGATCTTTACTTTGAGGAAAGTTTCACTTGCT GACGTGACAGTTGTGAGTGTTGTCATTCTGAGAATCTAAAGAAAATCAGTTTCTTGTTTT TCTGATTAGGTGACTGAGTGTGTGTGTGTGTGTGACATATAATTTTTAAAAATCACTACT TGATGACTCTTTGCTAGACACACTGTTTTAGAAGTGTGACTCTAAAGCTTTTGGCCTTGG TGTCTTTTTATGCTACTGTAATTAATTGCCTAGAGGTACAAAACAGCCTGAATTAATTTT TGTTGTCATTCCCATGCATGTTTAAATCATGTTACAACAGGCTGTGCATGGTGGCACATG CCTGTAATCCTGGCAATTTAGGAGACCAAGGTGGGCAGATTACTTAAGGTCAGGAGTCGC AGACGAGCCTGGTCAACACAGTGAAACCCCATCGCTACTAAAAATAACAAACAATAGCCG GTTGTGGTGGTGGGTGCCCGTAATCTCAGCTATTCTGGAGGCTGAGGCAGGAGAATTGCT TGAACCCATGAGGCAGAAGTTGCAGTGAGCCAAGCTTGTGCCACTTTAGCCTGAGTGACA GAGTGAGACTCCATCTCAAAAAGCAAACAAACAACCATAAATTCACAACATATGTGTGTG GTTCTGACTATGTGTAGAATTTGTTTTGACGTCTTAAATTTTCTTTTTTTTTTAAATTTT GATATGGCGTCTCGCTGTCTCGCCCATCTCGTTGTCTCGCCCAGGCTGGAGAGCAGTGGT GTGATCTTGGCGCACTGCAAGCTCCACCTCCCGGCTTCACGCCATTCTCCTGCCTGGGCC TCCCAAGTAGCTGGGAATCCAGGCGCCCACCACAACGCCTGGCTCATTCTTTGTATTTTT AGTAGAAACGGGGTTTCACCATGTTAGCCAGGATGGTCTTGACCTGCTGACCTTGTAATC CACCCACCTCGGCCTCCTAAAGTGCTGGGATTAGAGGCGTGAGCCACCGCGCCCGGCCCA GAGTCTTTTTACACTAGTACCATTTATTGCCTAGAAGTAACCAATATTCTAAACTACTTT TTAAAAGTATTCTTATGCATGTTTAAACATTTTCCAACATGTGTACGTGGTCATATTTAA TACATAAAATTTTTTTCAACTTCTAATGCATAGGTGGTTGTACAGTGTAATTTTTGACAA CATTCTGTTTTGATCAGCATTATAATTTTTAGAGACGTCCATAAAGGACACAATTAACTG TCTTTTTAAATGTCAGATTGTTTATAAAATTCCATTAAGTACACAATTATTATGCTGATA AATAAAAATGAAAACATGAAAATTTCAGAGTCTTTAAGTTAGTTATATCTACTGACTTTT TAGTTGTGAGAAATTAAAACTAAAATATTTAAAGTATTTCCTTGTGCAATCATACATTCC ACTAACAATTCCAACTGCGACCCACAGATTATTAGAGCTATGCTACTGCAACACATTAGA TCTCTGAAACGATCCAGGGTACACTTCTAAACATGAGTGAAAATGGTGGCATACCAAAGT ATGATTTTAGTTTCTTGGTCCCTCTGCATGAAATGTGAACTTTAGGGATGCTGAGATTAC ATGTTAAATTTACTTTTAAAAACCAGATACACAGTTGATGGATGTCAAATGATAAACGTA CCTTTAACGATGATACAGTCTTTTAGGCTTTAGTCGTGCATGTTTGCTTTTTTCTTTAAC CTGATTCAAAGAGTTGTAATGTGTACTTTTGGTTGATAAACAAAGCTGAACGTTATTTTT GGTATAAATTCATTTTCTGTCTCATTGGCCTGAGAGCTCCTCAAGTCTTGTGTGGGCCTT GATTTTATCCTATAACATGTGGGGATGTGAGATTACTTAGGGCAATTATTTTTTCCTATA CATTTCTGATGTTTCTCCTAGTTGTCACAAGCTGACTCTGAAGACATTGTTGAGTTAGGG GAGAACTATGTCATTGTAATTAAAGCAGTTCTTAATTTATATGCAATAAAAGTTTTTTAA GCTTATCTTCCTAAAACATATAGACACCCAAAACACACCCAATATACTGTCATGGCATAT TGAAATGTAAAAGTGTTGGACATATAGTTTACTAACATCAGAAAGTTAATATCCCTAAAA AATCTTGTTCGTTGATAAATCATCTTTTTTGAAGAACTGTGTAATAGAGATTGCAGAGTC AATCAAACTAAGTAATACTAGAAAATAAAAATTTACAAAGAAGTGAGAGATGATAGGTAA TTAAAGTTTTCTGAATGAACAGCAAGTATAGGACACACTGTGTTTCACGGGAGAAGAGGA TGTAACTGCTTTGTGAAGAAATAACTCTACGAGTTAGTCAAATTTCTATTTTTCTGCATT CTAACGAATGATATAATGTTAATTTTCCGTTTTTTTAGATTTCATTTCTAACGGATTGAC TATAGAAGTAGTGATTGTAATCAACAAAAAGAATATACGGGCTACAGAGGAAAAACCGCA GATTCGTGAATGAAAGTAGATTTATATATGTTTTTAAAGTTTATAGTAGAGAAATGTTCT CATGAATGTATCTGTGATTAACCTTTTATAGCTCAGATGTTCCCATCAGAATCCAAACAA AAGGATGATGAAGAAAATTCTTGGGATTTTGAGGTACTGTGTATTATTAATTTTCTTTAA TACTAGTATTGCATGATACAAAAACATAAAAGCAGAGGCTTAGACTTTATTTTCTCACCT CTGCATATGTCACTCCCAAATTATTTTTGATATTTTTCAGAATACGCTTAATAGAGGATC TATGTGCTAAGTAGATGACTGCTTCGTAGTGAAATTCTGCTAATTTTCAGGCTTAATTTA AGAAGCCGGTGTGGTATAGTGTAAAAAATAAGGCTTAGAAGTCACTAGAAATTCACATGG GATCTGAAGCAAGTTTGTCTAAAAGCAAAAGAATTACACTGAGTCCAGCTGTGGGCAAAT TTATGATTCTGTGGTGTATCTAGATGTGCAAAAGTTCTAACTGGATTCGTAGAGAGACAG TTTAAACTGCAGTATTGTAAAAGTTGGGACCTGAAAAGTTAATGCCTGGGACTTGAATGT ATTGACATTTCTGTATTGTTCAGTATAGATCTGAGGGAACATTTCAGGAGAAAGAGGAGC ATGAGGACTAGGAAACCTTGTGGGACTACAGTAACAAGAGTATTGGTTGAGTAATCTTTT GAAAAATATAAATTATTTTCACAAGTAGAACTCCTCGAGTCCCTTTGTGGCAGGCAGTCA AGCTGCAGCAGCATGAGTGTGAAATAATAGTGATGTATTTTAAGGTCACAACTGTGGAAA GACATAGAAAATATCTGACCTCTTAGAAACAAGCAGCTGCTGCCTGGTGGTAAGAGCAAA GGGTGGAAGTCAGTAGACAAGTAGATTTTATCTGATTTGTCGTCAGACAAAAAGACTTTA ATATTTGTTGGCTTTCATTTAGACATGACATAATTTCTTTTCTTACTGCATTTACATTCT CTTCAAGCACTTTTTCTATCAGCATAAATTTTGTCAAAAACATGTTGCTTGTTTTAAGCC CCTGTTTACCAAAATAAAGCAACTTTTTAAACATTCCGTGCATGCATTATATGACAGACT CTAAAAGTTCTCTTCACGGCATGCATCATTTTTAACACTAAACAATCTATGATCATGAAT ATTTTAAATGTTTAATGCAGTACGTGTTATGGCTAGTAGCAAGTGTATTGTATTTTGTTT GAAATGGCGTATTTACTTTTAATGAGGACTACAACACAAGTTAGATATTTTTAAGAGAGT TACTTTCTGAAATATGCACGAGTGAATTCTTTCGTGAGTGTGATTTGTTTTTCCTGCTCA GTAACCAAGTTAATAGCCTCATGAACGTAAAGGTAAGTTGATGTGGAGAGTGTTATGTGA GGTTTTCTATCAGAATGTTTTGGGTTTCAACACATGTCTGCTCTTAAGTCGAATTCCTTA TAAAGTAGGAAACTGTGTTTTTAGAAAAGATTTTAATTAGGAACTTTTGATACTCTTCAT TATTGGGATTTCTCCATTGAAATTATTTATTGATATTACTTTTAACAGAGTTTCCTTGAG GCTCTCTTACAGAATGATGGGTGTTTACCCAAGGCTACACATCAAAAAGAATTCGATACC TTAAGTGGAAAATTAGAAGGTAAGAACCATATTTTATTTAAAAAGTCATTTGACCAAATG TTTCTCTGAACTGATGAGGAGGGATATCCCCTAATAGCTGAAGAAAATTACCTCCTGAAT GCAAAGCATGGAAAAAAAGAGAAGTGAAATGGTGATAAGTTATACGTCTTATCATGTGTT GGCAGCAGACTACATAGAGAGTGCTGGAAAGGAACTGAATTATTAGTTTGAATTCAAGGT ATTCCAAGAGCTGAGGAAAATGAGAAAATAAGAAAGGAGAAAGTAGTAAAAGAGGAAATG AAGATCGAGAAAGACAGAGAGTACAGAGAGGACGGGAAGGAACAAGAGGCAGGTTTATAT AATGGAGGATGGTAAAATGAAATGATTCTTTAGGAAAAGATCGGGTATGGTTAGAAATTT GGGAAGAATATAAAGTGACTTTCCAGTGCCAAAACATACCAGAGAATTACAGCAAAAATA TTCTGACTCTTCCTGTCTTTCTCACTGGTGGGAAGCCATTAGGGATGGAAGCAGCTGACC ATGGAGAGCTGTGTTCTATTTGCAATAGTTGAGAATAAGCATATATGCACGGCCACACAT GTATATAATTTGTCATATACACTCCGTATAGACCGTAAGTTTTCAAACTTTAGAAAACCG TCTGAAAACCTTGTTAACAATTCACACTGTGATTCAGCCGACTAGGGATTCTGCATTTTT AGTAAGTTGTCAGGCGATGCTGATGCTGGTGGTCCTTGGACCTCAGACTGAGTAGCAAGA GGAGAGGCCTTTCATGGGAAAAATGTGGAAGAAGAGTAATTGGATAGAGGGTCAAAAGGA GAGGCCTTTCATGGGAGAAATGTGGAAGAAGAGTAATTGGATAAAGGGTCAAGACAGAAA AGGTTAGGAGAAAGCGTTATGTTGCTCTTACTTTTGAGTATGTTTTTAGCCAGAGAAGAA GAAAGAAAATTCTGAATTTATTGCTTGAATACCTAAATTGTTCTTATTCATAGGTATTAT AGTGATTTTAACATAGAAAATGTTATTAATATTTAATAAGTCTGTTGCAACTAAATTTAA AACAAATATGTCAATATTGAAAGCTTATTATATTTGCTATTCCTGATGAGTTTTGTACAT CTTCCTCCATGAGTGGATCAAGGAATATTGAGATGGCTAAGCTACAAAGTACAAAAATGT TGGCATACCGTTATGCCATATGGGTGTGAAAATTAGTGGATATTTATATTTAGTATTATT CTCTAAGTATATATCCAAGCTGATCAATTCATAACACTTTCACTGCTGAGATGTCAGTTC TACATTCAGCTGAACTCTCATCCAAACTTTTTACCTTCTCAGTGACAGGACATATTAAAG AACATGGTGAATATTTGTAATGTAATGATATAAATTATTATAATGTGTTGCATTAAAGAC ACATGGTATAGCATTCTACGTTCAGCTTTTGCATTTATTTTCTCAGTGTCACGATTTGCT CCTCTGATTCAGGATCACTTATCTCCTCATCACTCAGCATATACACATTGGCATTAACAC TTTTTGCAAAAATCACATATAAATGTTTGTAGAATGTTCTTGTCATTCCACAGTGATTTT TTATTTTTTTGTTCAGCGATTAGCTCGTTTTTCATTTATTTCAAGATTTCAGGCCGGGCA CTGTGGTTCACGCCTGTAATCCCAGCCCTTTGGGAGGCAGAGGCATGCGGATCACGAGGT CAGCAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTATGAAAAAATACAA AAAATTAGCCAAGCATGGTGGTGGGTGCCTCTAGTCCCAGCTACTCGGGAGGCTGAGGCA GGAGAATGTGAGAACCCATGAGGCAGAGATTGCAGTGAGCCAAGATCATGCACCTACACT CCAGCCTGGGTGACAGGGCCAGACTCTGTGAAAAAAAAAAAAAAAAAAGAATTTATTTAT TGTGGCACTATTCACAACAGCAAAGACTTGGAACCAAACCAAATGTCCAACAACGCTAGA CTGGATTAAGAAAGTATGGCACATATACACCATGGAACACTACGCAGCCATAAAAAATGA TAAGTTCATGTCCTTTGTAGGGACATGAATGAAACTGGAAACCATCATTCTCAGCAAACT CTCGCAAGGACAAAAAACCAAACACTGCGTGTTCTCACTCATAGGTGTGAATTGAACAAT GAGAACACATGGACACAGGAAGGGGAACATCACACTCCGGGGACTGTTGTGGGGTTGGAG GAGGGATAGCATTAGGAGATATACCTAATGCTAAATGACGAGTTAATGGGAACCTGCACA TTGTGCACATGTACCCTAAAACTTAAAGTATAATATTAAAATAAAAAATAAAGAAAACAT TTCTGACTGTGCATTTTTACTTTGCACTACGTTTAATTAGACTCTCTTCATGATGACTCA AAAGCAACATAAATATAATTACAGATGTCAACAAGGTTTTGTTTAAGTGTATGTCTTACT TCATGCTATATTAGAAATTAAAAGTGAAGTAATTAAAATGCAAGGATTCACAGCCATACA TTTCAATAGCCATTACAAATGTGGCTCACTAATCTTTAGAGCCATGCCATGTGACCTGTC CTGACTCTAAAAAACTCCAGTGTACACCTTTATAAAAATAAAAGTAATAAAAAAATAACA AAGGCAGTATTCCCCTGCTTCCTTCCTCTGCATGGATTTTGAACTTCAGGGGTAATCAGA TCACAATTTAGAACCAGAGTTTTCAACCATACATAGGATTCCTAAATGCCAAGTGATAAA CGGTTCGTTGATGATGAGATAGCTCTGAATGTTTCATCTCTGCATGTTTTGCTTTTTTAT CTTGTCTTAGAAAGGTCAAAGCCAGCTATTTTCTTCATAAAGGAAAATATTTTGGTTACA TATTCATTTCCTATCTCATGACACTCTGCTTTCTTTGCACTTAGTGAGGATGTACATTTA TCATATTTTTACCTAAAACAAACAGATGTATTAATGGTATCATTATATATGAAATTCTGA GGTTTCTTCAGTGCTTCAGAAGTAAAGTTTAAAGATATTAATGAATCGAGAATGACCTTC TCATCATAATTAAAGCAGGTTTTTATTTAAAGTGTGTTGAATACAATTTTAAGCACTTTT TTTATAAAACACCTACCTGCAATATGGTCATGTATTTAGCCTTAAAATGCTTGGACATAA ATTTTTTGTGTTTTAGAGAGTTTATATCCCTGAAGTGTCTTCATTATTGATCAATCATCT CTGAAGGGAAACAGCATATATACTTGATATGTCTAAATATATTAAAGTATGTTGTACTGA GAAATAAAAAGTAGAGAAAAATGAGAGATTAAGCATGTTTTATTCATATTATTTGATGAA AGGAGATATATTTCTATGTCAAAGAAATGTCTGTTTTTTCTTGAAGCTAAGTTTTTTATA AGAGCTTTTTCATAACAGTGTTTTAGCAACTCGCATTGTATAACAAACAGAATTAGTTTT AGCAACAAAATAATAAAACTGTTATTTTCAGTAACCATTATTCTAACATTGAAATATGCA GGTTAATGATATATAAAAATTCTCTGGAAATTGACTTCTAATTTTTGATACTTTCATATT AGGTGTTTTTTCTTTTTTTTAATTATACTTTAAGTTTTAGGGTACATGTGCACATTGTGC AGGTTAGTTACATATGTATACATGTGCCATGCTGGTGCGCTGCACCCACCAACTCGTCAT CTACCATTAGGTATATCTCCTAATGCTATCCCTCCCCCCTCCCCCCACCCTACAACAGTC CCCAGAGTGTGATGTTCCCCTTCCTGTGTCCATGTGTTCTCATTGTTCATTTCCCACCTA TTAGTGAGAATATGCGGTGTTTGGTTTCTTGTTCTTGTGATAGTTTACTGAGAATGATGA TTTCCAGTTTCATCCATGTCCCTACAAAGGACATGAACTCATCATTTTTTATGGCTGCAT AGAATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAGTCTATCATTGTTGGATATT TGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAATGCTGCAATAAACATACGTGTGCATG TGTCGTTATAGCAGCATGATTTATAGTCCTTTGGGTATATACCCAGTAATGGGATGGCTG GGTCAAATGGTATTTCCAGTTCTAGATCCCTGAGGAATCGCCACACTGACTTCCACAATG GTTGAACTAGTTTACAGTCCCACCAACAGTGTCAAAGTGTTCCTATTTCTCCACATCCTC TCCAGCACCTGTGGTTTTCTGACTTTTTAATGATTGCCATTCTAACTGGTGTGAGATGGT ATCTCATAGTGGTTTTGATTTGCATTTCTCTGATGGCCAGTGATGATGAGCATTTTTTCA TGTGTTTTTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGTCTGTTCATGTCCTTCGCCC ACTTTTTGATGGGGTTGTTTGTTTTTTTCTTGTAAATTTGTTTGAGTTCATTGTAGATTC TGGATATTAGCCCTTTGTCAGATGAGTAGGTTGCGAAAATTTTCTCCCATTCTGTAGGTT GCCTGTTCACTCTGATGGTAGTTTCCTTTGCTGTGCAGAAGCTCTTTAGTTTAATTAGAT CCCATTTGTCAATTTTGTCTTTTGTTGCCATTGCTTTTGGTGTTTTAGACATGAAGTCCT TGCCCATGCCTATGTCCTGAATGGTAATGCCTAGGTTTTCTTCTAGGGTTTTTATGGTTT TAGGTCTAACGTTTAAGTCTTTAATCCATCTTGAATTACTTTTTGTATAAGGTGTAAGGA AGGGATCCAGTTTCAGCTTTCTACATATGGCTCGCCAGTTTTCCCAGCACCATTTATTAA ATAGGGAATCCTTTCCCCATTGCTTGTTTTTCTCAGGTTTGTCAAAGATCAGATAGTTGT AGATATGTGGCGTTATTTCTGAGGGCTCTGTTCTGTTCCATTGATCTATATCTCTGTTTC GGTACCAGTACCATGCTGTTTTGGTTACTGTAGCCTTGTAGTATAGTTTGAAGTCAGGTA CTGTGATGCCTCCAGCTTTGTTCTTTTGGCTTAGGATTGACTTGGCGACACGGGCTCATT TTTGGTTCCATATGAACTTTAAAGTAGTTTTTTCCAATTCTGTGAAGAAAGTCATTGGTA GCTTGATGGGGATGGCATTGAATCTGTAAATAACCTTGGGCAGTATGGCCATTTTCACGA TATTGATTCTTCCTACCCATGAGCATGGAATGTTCTTCCATTTGTTTTATCCTCTTTTAT TTCATTGAGCAGTGGTTTGTAGTTCTCCTTGAAGAGGTCCTTCACATCCCTTGTAAGTTG GATTCCTATTTATTTTATTCTCTTTGAAGCAATTGTGAATGGGAGTTCACTCATGATTTG GCTCTCTGTTTGTCTGTTATTGGTGTATAAGAATGCTTGTGATTTTTGTACATTGATTTT GTATCCTGAGACTTTGCTGAATTTGCTTATCAGCTTAAGGAGATTTTGGGTTGAGACAAT GGGGTTTTCTAGATATACAATCATGTCGTTTGCAAAGAGGGACAATTTGACTTCCTCTTT TCCTAATTAAATACCCTTTATTTCCTTCTCCTGCCTCATTGCCCTGGCCAGAACTTCCAA CACTATGTTGAACAGGAGTGGTGAGAGAGGGCATCCCTGTATTGTGCCAGTTTTCAAAGG GAATGCTTCCAGTTTTTGCCCATTCAGTATGATATTGGCTGTGGGTTTGTCATAGATAGC TCTTATTATTTTGAGATACATCCCATCAATACCTAATTTATTGAGTGTTTTTAGCATGAA GGGTTGTTGAATTTTGTCAAAGGCTTTTTCTGCATCTATTGAGATAATCATGTGTTTTTT GTCTTTGGCTCTGTTTATATGCTGGATTACATTTATTGATTTGCATATATTGAACCAGCC TTGCATCCCAGGGATGAAGCCCACTTGATCATGGTGGATAAGCTTTTTGATGTGCTGCTG GATTCATTTTGCCAGTATTTTATTGAGGATTTTTGCATCAATGTTCATCAAGGATATTGG TCTAAAATTCTCTTTTTCTGTTGTGTCTCTGCCCGGCTTTGGTATCAGAATGATGCTGGC CTCATAAAATGAGTTAGGGAGGATTCCCTCTTTTTCTATTGATTGGAATAGTTTCAGAAG GAATGGTACCAGTTCCTCCTTGTACCACTGGTAGAATTCGGCTGTGAATCCATCTGGTCC TGGACTCTTTTTGGTTGGTAAACTATTGATTATTGCCACAATTTCAGATCCTGTTATTGT TCTATTCAGAGATTCAACTTCTTCCTGGTTTAGTCTTGGGAGAGTGTGTGTATCGAGGAA TTTATCTATTTATTCTAGATTTTCTAGTTTATTTGCGTAGAGGTGTTTGTAGTATTCTCT GATGGTAGTTTGTATTTCTGTGGGATCGGTGGTGATATCCCCTTTATCATTTTTTATTGC ATCTATTTGATTCTTCTCCCTTTTTTTCTTTATTAGTCTTGCTAGCGGTCTATCAATTTT GTTGATCCTTTCAAAAAACCAGCTCCTGGATTCATTAATTTTTTGAACGGTTTTTTGTGT CTCTATTTCCTTCAGTTCTGCTCTGATTTTAGTTATTTCTTGCCTTCTACTAGCTTTTGA ATGTGTTTGTTCTTGCTTTTCTAGTTCTTTTAATTGTGATGTTAGGGTGTTTTTTCTTTT GTTGAGACAGAGTCTCACTCTGTCATCCAGGCTGGAGCGCAGTGGCACGATCTTGACTCA CTGCCACCTCCGCCTCCTGGGTTCAAGTGATTCTCACAGCTCCGGCTCCCAAGTAGCTGG GGTTACAGGCATGTGCCACCATACCTGGATGATTTTTGTATTTTTTGTGGAGACAGGGTT TCGCTATTTTGGCCAGGCTGCTTTGGAACTCCTGGACTCGAGAGATCCGCCCTCTTCAGG CTTCCAAGGTTCTGGAGTTACAGGCATGAGCCATGGCACCTGGACTGTATTAGTTTGTTG ATGGGTATGCTTTGACTTTTCTGTATAAGTGGATCAGGAAATTTTAAGAAGACTAAACTA CAGAACCCCAGAAATATAAAAATACTCGTATTTCACAGAGGTTCAAAAATAAATATATTT ATAAACTTTCATTCTATAAGTAGATATTTATGCTGTTGAATTTAGAACATTCTCTGCAAT GATAAGTAAATTGTACCTTTGAATTCTCATCGGAGCTTTGCAATTCTTAAATTACAGGAC AAATTGAAGAACATAATAGCTACTTGTAGTATATTGACATAAGTGATTCTGATGTGTTTC TTTAATAATATGTCATAGCATTCTACCATTAGCTTGGACATTTATTTATTTATTTTTGGT GGAGGGGTCATGTCTTGGTCATCTTACTAAATTCAACCTCTTTCCTTATATGGCAGCTTA CTCTTACTGGTATTAGGATTTTCTGCTTTAGTTAATGTCACTTGAAATATATTTTGACTG TTGAAATCTTCACAGCATGTTTGAGGAAATTTATTTTTTAAATTTTCTTAGGTATATTTC TGTCACTCTGGCATGTTAACAAACACAATAACCCAAAAGACCCCAAAACCTAGTGTAATC TCTTTTCAATCCAAGCATGAGGATTCATCTTCATATTCACACTGCATGAATGTTTGGTAG ACTTTGACAGGCTTGCGTATAATCAATTATATATGTCCCTTTTCTTTTAGAGTCTCCTGA TAAAGATGGTCTTCTGAAGGTAATAACTTTTATATTTTTATCTTGAATATTAACTACTTA TTTTATGAAGTATACATTATATAGTAATTATTGTGTTTCCAAACCCATTTAGCCTACCTG TGGAATGAAAATTTCTCTTCCAAATAAAGCCTTAGAATTGAAGGACAGAGAAACATTCAA AGCAGGTAAATTTTGTAATTTTAATTTTACTGTGGAATTAAGAACATTAAAATATTTGAA GTGCCAAGAGCCTTTTTATTCCCAATGTTGTTTTCTTTTCAAAATTGGATGGGAAAATTT GACACAAATAATGCCAATGTTAGTATTCATGTTTGAGAAAATGCCATTTACAAGCGTAAG ATTTAGAGATTTAAAAAAAATTCTACTGTACCTCATGTGGTTCTTCTTTAATATCCTGAT ACTATAAAGTTTCCAATTTGCAATTTCTATACGTGCTTGGTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGC TCTGTCGCCCAGGTCGGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCC GCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCG CCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTT AGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGC TGGGATTACAGGCGTGAGCCACCGCGCCCGGCCACGTGCTTGGTTTTAAGGCAGGTGAAT TTTGACACTGTGAAATATTTGCAGTGGTTCAAATGCTGATTGGAATTCTGATCTTTACTT TGAATAAAGTTTCACTTGCTGACATGACAGTTGTGAGTGTTGTCACTCTGAGAATCTAAA GAAAATCGGTTTCTTGTTTTTCTGATTAGGTGATTGTGTGTGTGTGCGTGTGTGACTTAT AATTTTTAAAAATCATTACTTGATGACTCTTTGCTAGACACGGTGTTTTAGAAGCGTGAC TCTAAAGCACTTGGCCTTAGTATCTTTTTATGCTACTGTAATTAATTGCCTAGAGGTACA AAACAGCCTGAATTAGCTTTTGTTGTCATTCCCATGCATGTTTAAAATATGTTACAACAG GCTGTGCATGGTGGCACATGCCTGTAATCCTAGCATTTTGGGAGACCAAGGTGGGCAGAT AACTGAAGGTTAGGAGTTCCAGACCAGCCTGGTCAACATAGTGAAACCCTATCTCTACTA AAAATAACAAACAATAGCCGGTTGTGGTGGTGGGTGCCTGTAATCTCAGCTACTCTTGAG GCTGAGGCAGGAGAATTGCTTGAACCTAAGAGGCAGAAGTTGCAGTGAGCAAAGATCGTG CCACTCCAGCCTTGGTAACAGAGTGAGACTCCCATCTCAAAAAGCAAACAAGCAAACAAA CAAAACCCCAGAAATTCACCACATATGTGTGTGGTTCTAGACTATGTCTAGAATTTGTTT TCATGTCTTAAATTTTCAATAAATAGTTGTACACTGTACATATTATTTTGGAACTTCCTT TTTTTTTACTTATCTTATATTTTAGGTGTACTCAATACAGTTAGCTCCGCTTTGATTTCA GGCTTCATAGTTTGCGATTTTAACTCTAAAACACATTTAATTAGGCTGTCTTTCATAGCC ACTGAAAGTCAACATCAAATGATAGCTTATATCAGAGAGCTTTTATTGAAGTGGGAATAT TTACTGCTTCAACTAATATTAGAAATTAAAATGAAAATATTTAAAATACTGGAATGCATT TTAAATATTTGTGTTTTTGGAGATGGAGTTTCCCTCTTTCGCCCAGGCTGGAGTGCAACG GTGTGATCTTACCTCACTACCCCCTCTGCCTCCTGGACTCAAGTGATTCTCCTCCATCAG CCTCTGAGTACAAATACTCATTTGTAAACCAGTCACTAGAAAAGCAAATGTTCTTACTGT GATTAGCTTAGAATAATGATTTCTCATTTTGTAGATGAGATGGGAGTAATGGAATAATAA ATATGTAAATAAACTTGTGTTTCTGCTGTAAGAAAGAAAAAATAATTTCTATGCATTGGA AGCCAGCAATGTTTTCTGCACAGATTCATTGGAATTATTTGAGCAGGGGAGTCCCAAGAT TAGATTTAAGTATCAGAGCATTCTGGTCATGGTATAAACCAGACATTGGCAAACTTTTCT TGTAAAGTGCCAAACAGGAAATATATTAGGTGATGTGGTCTCTATCACAGCTTTTCAACT CTACCATTGTAGCATGAAAGCAGTCATAGATAACATGTGAAGAAATAGGTGTGATTGTAC TCCTATAAAACTTTGTCTAAAATCCATTTGGTAAGCTGAATTTGGAATTCCATAACCATG GGTTGTGGAATACAACAGTTTGCATTGTGTCCCTTAATTGAGGGACCACGATACCAAGTC TCCACTAGCTTTAAGCAGCTTTTTCAATACTTTCATATACTGTTTCTTTTGTGCTGATAA TTGTTGTCCCATGATGAAACCCTCGCCTGAACAATTTCCCCCGAACCTGGAAATCCTGAG CAGGCACCAATGACTTACTCGCTGCCTGTGCAGTTCTTTTCACCTTCATATTTGAGGGTT CCATCACGATCCTTTTGCATAGTTTGTCTTGCCACCTGCCGGGTCCATCCCATGGACACT GACCTAAGTGACAGATGAGAGACATATACTGAAACAGATTTTTTGCCTGTCAGTGCAGCT AAGGGGTTCTGCTGCCTGAGTCTGCATTCTTGGCCTCGATAAGCCTGCAAAGTTCACATT TATTTAGTACAGATTAAATGACAAAACTGTTGAGTAAACATCACTAGAGGGTAATTAAGA TTGCCAACCCCCAGTACAAAGCAATCATGCACCCTCGGATGATCAAACTTTTGTCTTAGG ACCACGTGAGTAAACAAGGTATTTAGATAAACTCCTCCACATTCCCTAGATATTTGCTCT ATTGCTACCAACTCAAAGTAAAGAAGATTAGGCTGTTTTCAGCCAAATCATTTACTGAAG CTATGCAACCCCCCGGCCTTCCAAGAAGGTTTGTGTCTATTTCCTATAACTATCTTTATA ATTTTTTTAACCACTTTGTCCGATCCCCTACAGGTAGGGTTGCTTTTTTCCTGTGAAAGC CATCAGTTAAGAGGCCATGTCTAACTAGGAAATATAAATATAAAATAAATAAGTTTGTAT TTCCAGTGGCAATGGAAAGATAAAGCAAATGCAGAAAAGAGGTACAGTTAATATGATTTA GTGATTATTGATTTGAAAAAGCTAGGGGAGAGAAGAAATTTCAGGTCATTCATAAGTTTC CACATGGGGAATGCTCATGGGGAAGGAGTAAGAAATTGTCAGGTCAACAGAAAAGTGCAA ACAGTCATGGGACAGACCAACCGTTTTCTTTACATATTGAGTTCAATGAAACATTCATGT GGGATATTTTCAGTAGGTAATTGGTTTATACGTATTTCTAGCTGGAGATAGAACTCTGGT TGGAGATGCAGGCTTAGAATAATTTTATTATAATTATTAAGCAAAGCCATAGATCTCACT GAGCTTATCCATGATGCAGAAGATGTAGAATAAGAAGAAAGCCATTGACAAAATCCTGGG AGTATCAACATTTCACAGAGTCACAGGACTTGGTAAAGGAGACTGAGCAGTGGCTAATGA AAAGTAGGAGAGGAGTCAGAGAAAGTGATGTTGCAAATTTCTTTTAAATATGAGAATTTC AGCAGTAAGATTATAACTGAAAAGTCAATTGGATTTAACTTACAAGTTCTACAGTGGTAA TCTGTTCAAAAGAATTATTTTAGAGTTGTTAGGTATAATGTTGATGTAGTTAATATTTCT GGAGTCCAAGAGGAAATCTCCCAAGATCCTACCTAACTTTTTGCAACTAAAGCAGCATAT ATACACAGGGTCTAGGAAATTGTCTAGACTGGGGAGTACACATGCCAGCATTTTTCCAGA ATTGTCAAAACCTAAGGGTCATGTGTGAGGAAAAGTGTTGTCTTTTTTATCTGCTTCTTG TGGAGAGTGGAGATCTGTATTGTTTCTCTCTCTCTCTCTCTCCCCCTCTCTCTCTCTCTC TCACACACACACACACACACACACACACACACACAAGTACAGTAATTCATCCTTATCCAA GGCGTGTATTTTCTAAGACACCCATTGAATGTCTGAAACTGTGGATAGTATGGAACCCTA TACATCCATGCTTTTTTTCTTCTATAAGTGCATATTTGTGATAAAGTTTAATTCATAAAT TAGGCACAGTGAGAGATTAACAGGAACTCATAATAAAATATAACAATAACAATATATTGT AATCTCAAAGTTAGGTGAATATGGTCCCTCAAAGTGTCTTGTATTGTACTCGCCCTTCTT TTTCTTGTGATGACTGTGAGATGATATAATGCCTATGTGATGAGATGAAGTCAGATGAAT GAGGTAGGAGTTGTCATGTGGTGTTAGGCTACTAATTATTTCTTGCTGTCTGACCACACA TCAGAAGGAGGATCATCTGCTTCATGTGACCCTGGATCATTGAGCCATGATAATGTTGAT GGTTGGGATACAGGAACAGACCATTTTGATGACTAATGGGCAGATAGCATATACAAAGGG ATGATTCATGACCTGGATGAGATGGAACAGGATGCCTTAATATTTCATTGTACTCCTTAG AATGACACATTATTTAGGACTTATGACTTGTATATTTCTGGAATTCCACATTTAATATTT TTGGACTATCATTGACCATGAGTAACTGAAATCACAGAAATTAAAGAGACCCAGATTTGC AACTGGTGTGTGAGGGAAGTCTTGTGAGACTGAGCACTCAGTCTGTGGGATCTGAGACTA TTTCTAGATAGACAGGGTTGGAATTAAATAGAGGACAGTCAGCTGTTTTTTTCTACAGAA TTCATTGCTTATTTGTTGGTGGAGAAAATCCTCCACACATTTGGTCGCAGATGTCTTCTG TTTTAATGATTTTGGTATGAGAGCAGAGGGAAATCATGTTGTGTGTGTTTCTTTCTACAC ATACAGCAGATAAGAGACTACTGTATACTCTGTTCTAACTGCTTCTAGTCCATTTGTCTA GAAATTATACTTTCTAAGTTTGACACTGTCCACTTATACTAATTCTGCTAATAATACAGT TTTCTGTCAGTCTTATAGGGTTCTGTTTGGATGATGACTATTGTACACTGTAGTTCACTT GCAGAGATCAAATTGTGATAAATTCCATTTTTCCTTGCATTTGAGAACTACAAAGGAGGG GAAATAAGCATTCTTAATGCATTAATTTCCTACCAATAGTATACTTAATAATAATTTTAC TATAGTCTCAACGTATGGTCCCAAAAGAATGCTTTGTAACAAATCATCTGAGTCTTTGTA ACAAAGTGTCAGAGTATTATGCTTTTTAAACCAAGACCTTAATCATGCATGAAAGTGTGC GTGATTCTTTTAAGTTAAGTTGAAGTCTTGCAATGTCTCCCAGGCTGCTTTCAGACTCCT GGACCTCTCAGATGATCCTCCTGCCTCACCTTCCCAAGTAGCTGGGATTACAGGCATGTG CCATCGTGCCCTCTTATGTTTTTAATATTCTGTATTTTTTATTTATATTTGTTGATTTAA TGTATTTTACTCTTTTCTTTAATAGAGGATGTGAGTTCTGTAGAGTCCACATTCAGGTAA GACTTTGCGGTTTTTTAAAACGTATATGTTAACTCAGAAAATATAGAGAAAAGAAATCAC TATCTGCTGAGTATTCTACTCTGGGCTAGACAACGTATTATGTGCTTAATATTTATCATC TCACATAGTCATCACACAGCTTTGCAAAGCATCTGTGCTACTGTCACCTACTTTGTATTA ATCAGGCAAATGTGATTCAGAGAGGTTGATTAATTGGCCTATGATGTCATAGCTAAAAAG TAGCTGACCCTTGAGTTTGCCATCTGCTTACCTTGCTCCCTAATCCCTTCCCTTCCCCCT TGGCATAGATTGATGGAGACCTGTGGATCACTAGGATCAAGGTACAGGACCAGATGGGAT CAATTCACAAAGTCACATTTTGTTATATGTTAACTCTTTTTAGAGATTTCCCATAGAACA TTGATTAATCCAAGACTTTGTTCTAACATGTTTAACCGTTAAAGTGGTAACCAGTACCTT GTTTTTATCACCAACGTTTTTAGAGCAGATCTTACTTAGCTGTGGCCACAAGACATAGGC TTTTGTTTCATATGCAATACCAGGTAAATCCTATAGATGGATTATTTCACTCTTAGTGGA GAATATCTACATATAGATATGTTAATCATATTTAGAGGCTATTTCTTATAGAATTCTCTA TTTACTGACTTCTTAGTTTAGTTCTTCTTCAAAGCAGTCCCCTCTTAGTTGCATGCACTC TTCATTTTCTTTTCTAGAGTCTTTTCTCTTCTTTCATGACTTATTTATAATCTTTTCCTG ATTACTTTCTTCTCTGCTTTCCTTGGTGTTCTTTTCTTCTATTATTTTATTTCTTTCTGC CAGCCCCATTTTTCTATAGCTAAAATTAAAGCACATGGAATTTTAGGATTTTAAGGACTC TTGGAGACTAATCAAAATACTTTCATATTTTAAACTCTATTTAATATCCTGGAAAAATTG TTGTTCACATGGAGAATCTGAAACTCAAAATGACTTATTTAAATATAAGAGGTAGCAGAA GTAATATTTAAACTCATTTCAAAGCCCATTACTCTTGTTTTTATATCATCATGTAAGTGA GTGTTTGAATAATAGAAAGGAAAAGGGGATGGATCTGATTAAACAAATGGAAAAGAATAA TGGAATTAGCTGGAAAACCCAGTAGAAGTAGATAAGAATGGAATTATCAGGGAAAGGCCA AGTTTGAAGAGAAACAATCCCAGGATTGGTAGGAGTAAGGGTTTTACCAAAGAGATCAGA ATATTGGATCTTATGACAAGTTTGATGAAGATAAATTAGAGGACCAAAAACACAGAAGAC ATTGGGAGTTATCTAGAAAGGCATACTAAAATAGGGTTCAAAGAAGTCCTGAATAGATTG CTGCTTTTTTTGCTTGTTTAATTGGAGGAATGGGCAAACTTCAAGATTTCTATTGAAAGA TTTAGAAAAAAAGACCAACTCAGAAAAGTCTCCACAATCAGAATAGAAATGTCCTATTCT GTTCTTTCACCCCAAATCTCACAGGAGTGGCTTAGAGCCCCTTCAGTGCTAGGGGATTGA AGGTTGCTGAATTACATAGATCTGTGGCCTAAGGCAGGTGTCCCCTCCCGTTTGCCTCTT TTTCCAAGCCTCTGATGTCCTACCCATGTACATGTAAAGCAGGGGGAAGATTGGCTGTCA AATTAGTCATGGAGCTTCAGTTGGGTTTTTGGTAACATGACTGAGACTCTGTTTAGTTGT TTTTCAGGAACAGGTAAATACAGAGCTTATTGGTTGGTCATTGAGTTTATCTTTTCAGTA ATCTGTGCTTAGATGAGCTAAATATTTAAAGGTTGGAGACTGCCATGAAGCTCTGCAGAA GAAAGATCTGGAAGTGGGAGACACTTTCACTATATATAGTGGCTCCCACTTCCAGATCTT TCTCTCTGTATATATAGTACTTAGAGAAATCCAACTATCAGGACTCAGTTTTTCTAGCAG TCTCTCTCCTTGGGTATAAGTACCTACGAAGATTTTTAAGGCTTTGCTAGTTTATGTAGA CCTGAACAAGGAAGGAAAAGTATAAAATAAGTAGTTAGACTTTCTTACTTTTAATGTTTC AATTTTTGTGAGAAAAATATTCCCAATAACAAATATAGATTTGTATTTTGACATTTGTAG GTTCAGCTTTTCAACATTTCAGATATTTCAGGGCACTCTCTTGTAGCGTTTTAGGGTGAA GGGAAGCAACAAGGCCTTTTTAAGTGGTTTTTATGCTGAAAAACAAAGAATGTCATTTTC CAGTGACACAGATTAGTCTTTGAATCAGAGATAGACAATGGATAAGGGACAAGGTAACTG TACCTTTCTTCCTCATTTTAGGTTATCAAGTTTGTTCCAGTTTAGATATCAAAAGTTATG TCAGCCATTAAGTACATTTTCAGTTCATCATAGAGGACAGCTTGTGAGGACTAATTATAC TCAGGGTATGCCAATTATATTGGCGGTCACTATTTTTTATGGAACTAAGAGTGAGTGTTC ATTGGATGTTACAGGTTGGAGAGATAGAGTCAAAAATAGGTAAATGCAATCTTTTTTAAA AACAGAGGGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGG CGGGCAGATCACGAGGTCAGGAGATGGAAACCATCCTGGCTAACACGGTGAAACCCCGTC TCTACTAAAAATACAAAAAATTAGCCGGGCGCAGTGGCGGGCTCCAGCCCCAGCTACTGG GGAGGCTGAGGCAGGAGAATGGCATGAACCCCGGGAGGCAGAGCTTGCAGTGAGCAGAAA TCGAGCCATCTCACTCCAGTCTGGGCGACAGAGCGAGACTCCGTCTCGGAAAAAAAAAAA AAAAAAAACGAAAACCAGATGGCATATTTTAATTATGCCAAGAAACATGATTTAATATAT TGAGGACTGATCTTTCCCCAGATTTTGTTTTTTGTTCTCATTTTTTGGAGTGAGCACTAA GATATGAACTGGCAGGTTTTCTTTTTAAATATATGAATTTGCTCATTTTTGTTTTATCTT TTTTCTCTAGTCTTTTTGGCAAACCGACTACTGAAAATTCACAGTCTACAAAAGTTGAGG AAGACTTTAATCTTACTACCAAGGTAAAATAGTCTCTTGTTAAATTGATTTTCTCAGTTG GAATCTAATTCTGTATAGTATTTACTTTTCATGTTTAGCAGTGGTGTATGTATCATAATT TCATGTTGGTAATATAAAGTTGGTCACATAAAAACATTTTATAGAAATATGAGTAGTTGA TTTAAACAGTTTTTTTTTTGTTTTTTTGTTTGTTTGTTTTACTTCAGTAAATAACAAATG ATTGGTAAATACTCTGAGGGTGTGAGGGCCAAAAACCGGAATGGGCTGTAGAAATACATA GTGACAGGAACATTATATTAGAAAAAACTTTTCCACAATAGAGAATATATAAAATCTGGT AAAGGTTTCTTTGCATAAGTAAACTTACTGTGACTTTTAAAATTATTCTATTGTAACTTT AAAAACACCTCATCCTTAAAATTATCTTTAATGGATCCAGTTACTTATTACAGTAATCAA GGAATCTGTCTGATAAACTTCAGTTCTGAAACTGTGCCACATAGCATATAGGTTTTTTTG GCGCATATTATTTTGATATCATGTAGTTTTTAGGAGAGAGCTTTTTATCAGTTTCTCTTC TTGGTTCTTTAATTAAACACCAAAATAATATTAGAAATTGTGAAAATTTATTTGGGCATG ATGGTGCATGCCTGTAGTTCCAGCTACCAAGGAGGCTGATGCAGGAGGATTGCTTGAGCC CAAGAGTTTGAGACCAGTGTGGGCACATAGCGAGACCTTATCTCTAATTTTGAATATAAT TTAGAAATTTAGAAATGTAAATTCTCTTTCTCAGAATCTGTATTATTAAGGCATGTGAGG ATGTTTTCTAAGTTATTTCATTAAAAGTATACTTTAAATTCTTCAACTAAATGAAGAATG CAGGTTTCACCCCAAGTAAAAAACCAGTTCTGGAAGCAGAGACTCTTAATAAGCATATGG TAAGATTTTAATTTCAGAGTTTTTAAATTGCAGTTTTTAAACATATTGTTCAAAGATCTT TGATCACATTTGAAAATTTTAAATTTCAGAAGATTTTGTATTTAGTTATTTAAATAATCG TTTTGGAGCTCTTGCATCACTATGAGATACTGCAGGTTAGAAAACATACTTGTGTGCATC CTAGTGTACCCAGAATACAGTCTTGCCTGTAAAAAGCATTTTAAGCGGTTTTCAATGTGA ATAAATAAGCAAATGAATTTTTATGTAATGGAATGTTACAAGTAAGATAATATGCATAAT ATACCTTATAATTAAATCTAATGCGTTTCTAAAATATGACTTAAATTTATATTTTCTTTT AATATTTAGAATGCATAAATTAATGTGCGTTATCTTGAGAAAATATGTCATAAATAAGAA GACAATAAATCAGAGATATGTAGTAAATAGGAAAGAAGATTACACTATATTTTCTAGTAT CCCCAAGTGGAGTTCAGATTTTAAAAAATTTAATATATTTTAGTCTCAACTCATGTTTTG TTTGTTTGCTTTTTGTTTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGTTGTAGTGCA GTGGCGTGATCTCGGCTGACTGCAACCTCTGCCTTCTTGGTTCAAGTAATTCTCCTGCGT CAGCCTCCTGTGTAGCTGGGACAGCAGGTTCATGCCACCATGCCCAGCTAATTTTTGTAT TTTTAGTAGAGACAGGGTGTCACCATGTTGCCCAGGATGGTGTCGATCTCTTCACCTCGT GATCTGCCCTCCTAGGCCTCCCCAAAATCCTGGGATTACAGGCGAGAACCACCGCGTCCA GCCGAAACTCATGTTCTTTTTTTTTTCTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAG GTTGGAGTGCAGTGGCGCCATGTGGGCTCACTTGCAAGCCCCACCTCCCGGGTTCACACC ATTCTCCTGCCTCAGCCTCCAGAGCAACTGGAACTACAGGCATCCGCCACCACGCCCAGC TAATCTTTTCTATTTTTAATAGAGAGGGGGTTTCATCGTGTTAGCCAGGACGAAACTCAT GTTCTATTAAACATATCTTTTCAAGGAATACATTACTCTAAAATTCTGATTACCAATACT TTCTTCAGGTGAAAAGTTTATGAAACATTCATTTTTAAATTTTTTCTCTCTCTGTAGTAA GAATATTCTCGCTTTTAGGTGTTGGCTGAAGACCATGTTTAACTAATTGTCTTATTATGT AATATTAAAATTAAAATCTTTATTACACAAGTATTAACAAAATAACAAATTGTAGTGTAA ATACTGATCAGCAATATTATTAACAAAAGTCTGTATTATTTGTATTTCATCACATGTCTT AGGGTAGCTGTTTCTCCTTTTCTTTCACGACTGAAGCTCATGATTGACGCATCATGGCTC TTGTTTGTTTCTTCCGCCTCCTTCACCTTTTAAAAAATGATTTACCCCAGACTTTTTTAA TCACAGAATACATTTCTTCAGTGTCTGCTTTTGAGGGCATCTCTGTCTCAATTGTCAGCA TATTTATTTACAGGTCTCTATTTAGTTGCTATGTATGATTTTCATTACTCAATCATTGCC CCCCGCATGATTTATTCTTTTTTCTCTGTTTCTTGGAAGAAGCAGAATTTATACGATTAT TTATTCTTAGCTTTTTGCCACACAGAATAGAAACAACCTATACCATTTCAATGCAAACCC AGTTAAATAAGGTACTATTAAAAACTAAACTCTCACATTTTTCCATACAAGAGGTAATTA ATACAACTGTAAATTGTGAAGAGATATTTCAAAATATAACATGTAATTTTAAAATTTTAA TTATTTCTACAGTACTATAAACTGTGTAAGAATAAATTTTTGTCGTAGGTAATTTTGATT AAAAAAAATCTAATGGATACCAACATATTTGTATAATAATAAATTAGATGAAGGGGATAA TAGGAAATAATTCATTGAAGAAGGGTAAGATAAACACAGAGACTACATGAGAGAGGATGA GACAGATTCTTATAAAAGCACAGCAAAAATAGTGGTTTAAATGAGAGCAGGAACTCTCTA GAATAAAAGATATGATATAAATTATTTAAAATAAAAATTAAGAAAACATAGCCAGCTAAT AAAAGATAGCTCAGGTGTTTTTGAGTGACTTATAGCTGATTTTAATAAAAAGCTGACAGA AAATATAAGGACGAGTATAGGTAGGAGCAATTTGTTGTACTCTTTAAAATACCTAGTAGA GAATAATTTGAATGTTTCTAGCATAAAGGAAAGATAAATACTTAAGGTGATTAATATCTC AATTATTCTGATTTGATTATGTGAATGTATTAAGTGATAATATGTACCCCCAAAACGTAC ATTTATAGTGTGTCAACAAAAAAATTATAAACAAGGAATGAAAATTTAATTCTTACTTCT TTTAGTAACTTTATGTCTTATATTTAATCTAGTCATACTTATAATTTTGTAGAATGCAAA GTGAAATCTGTTTTAGGCCTTGCCAACTTTATTGTGAATTATTACTTTTTGATTCTTTGG TTTCTGGTTTAAGATTTCTAACTTAATATTTGACATATTCTTAGGTTATTTAACTAATTT ATCTTACTCTTTTATATAACCTTGGTAGCTGTTTTGAATATTTTTGATAATAGAGTATAA ATAAGCATTTTATTTAAACTTGTTATTAAAATTAAAGTTTCTGATCATATGAACATGGTT CTTAATCTGTCTCTTAAAAGAGAAGAATCACTTTTAAGCTACAACACTGTCAAAGAAATG TAGAAATTATTAATCTCTAGAAATACTCTGACATTTTTGCTCATAATATAGGTATGTAAT GGTATTATATACACACATCAAATGAATGTAATCAGTATTTGTCAATTGTTTTAAAGTAAA GTACCTATTATCATAGAATCATACGTAAGGGAAGATTTAACAGAGTAAACAAACTTATCA TTGGAAGAATACTTTTTACACTTAAAAGTATCTCTTGCAATGGGGATATTTTATATTATT TCCAGGAAGCCTTATTAACTTTAGTCTTCATAACTATTACACCTTGCACATATATTTGTT TATTTCTAAAACTCAGGAATCTTGTTGACTTGAACTTTTTAGTTTCTTTCTTCACTTCTC CTATGAATACTGAATTCTGCTTGACAATCATAGATATATGTAAAAACTATTAAATCATCA ACTTGAATAATTGTTGCTTAATTTTCTTTATATGAAATCTTTTCTCCAATTTTAAACTAC CATCCTATATGGTGTAAATAGGCAATTTGAGCTAGTATTATATTGTTTCATAAGAAAAGC ATGTGAATTTTAAAACAGAGTTTCACATTTCTATCTCACTTTATAGTAGTACTTAAAAAT GCCTTATAATTCTATGGGTAAGCATTTCTCTTGTACAATTAAAAATTTCAAGGTTTTTAT AAAGGTCATTTTGCAGAATCTTGTTTTAGAATTAAATGTTTTCATTCAATTCAAAGATGC ATATTGCAAAAAATATTTCAGAAATAAATATTTACCTATATAAATAAAATTATATTCTTG AAATAAATTTGGAAATATATAACTGAGAAACTTAATCCCATGTTTTTCTCTCTCCTTTGA TTTCATTTTCAAAATTTCAGCAGTCTGCATAGATTTGTGTTGCTTAATTCTACCCATTTA GTCTATCTTATAAATATTTATTTTCTAATCACTATGTAATTTTCCTCATGTAGGTCATCT ACTCATACTCCAAATGTATTTATCTAGATCTTTCTTCTAAGCCCCATAGATGCCTCAAAT CTTATAGGTCTCAAACTGAAAACATCATTTTTATTTTTTTCTGACTCTTTTCTGACTCTT TGTAATCTACTCTGTCATCTGGTTTCCCCATCCTAGTAAATAACAACTAGGAAGTAGCCA TGAAATGCTCAAGCACTTCAACCGGCACTTCAACCGTCCCCTACATCCTGCACTTCAACC CTTCTCCATGTCACCCATCCAGTCACACACCTAATTTTGTATTTTCTGCCTTCTTATAAT TTTCCATATCTTATTACCATAATTAACTCTCTACCTATAATTTTGAAGTACTCCTTTCTA GTTTTGCCCCATCTCCCCATGTTCATCTTTACATCACTGGAAAAGTCACCTTTCTAAAAT ATACTTGTAATGATGTAACTCATCTGCATATTGAGTGGATACCCATTACATGAAGGGGTA AGTTCACATTCTAGGGTGATATATATCTTATATGGTTTGGTCTCATTTTATCTCTTTAAC TCATTTGCTCTGACTGTGTTCCAGTTTTACCACATCACTCTGGCATCCCTCAGTGGCCAT GTTGTTTCATGCCTTATTATTTTGCACATGCTATTGCACCTAGAGTCTTTGTATCCTGAC TCTGCACGTTGTCTGTCCTTCCCAATATGGCCCCATTATGGCAGCATTTTCTAAGCTTTT CAGGTAAAACTGATTTTTCTCTCCTTTGTGCCCTTATGTATTTTATTGACTTAAATTGTA GAACTGGTGAATTTTACTTTTCTGTTCTTATTTGTTTTCACATATCTCTACCATTTCTTG AACATAAGCCAGAATCTATCTTCCATGTATATTTTCTGCTTCTCCCAGGATAGTGCCTAT GATTTGACAGATACAAAGTATGTTTTTTGTTGTTGTTGTTGTTTGTCTTTCTGACAAATT GATTGAGTGAGTGAATAAATACAATTTTTTTCTGAAGTTTTTTTTTTGTGTTTGCTTTCT GTGTTTTGTTTGTAATAGGAGGGAGCAACAAAGACAGTAACTGGACAACAGGAACGTGAT ATTGGCATTATTGAACGAGCTCCACAAGATCAAACAAGTAATGACAATTTTATTTTTTAT ACCAAAATAATAGAAATGGTAAATTAGTGAATATCTCTGAAAATTTTTCTATGTTTAAAT GCTGTTATATAGAAAACAATTTTTTAGCCCAAAATACAATGTCTACTTAAAAAAGTACAT TTTGATATCTTTCTTCATACTATCAACTCTTTTTTTTCTGAACCTGCTTCAATTCTGAAA TTCTATTTTTGCTATTATTTTTATTTTTGAAATACTCATAAATGGAAATAGATTTGTATA TAGTTTTATGATTTACAGTAATAAACATTCTCATATACATGTCTGTGAATAACATTTTGT AGATAAGATGCCCACATCAGAATTAGGAAGAAAAGAAGATACAAAATCAACTTCAGATTC TGAGGTACTGTGTATTGTTGTTGTTGTTATTTTAAAACTTAAGTACTCAGTAATCTTAAA ACATAAAAAGATGATTTGACTTTATTCTCTCACCTCTGATTATGTCCATAAGGCGGGTGG ATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAATCTCGTCTCTACTA AAAATACAAAAAATTTAGCTGGGCATGGTGGCGGGCACCTGTAGTCCCAGCTATTTGGGA GACTGAGGCAGGAGAATGGCGTGAACCCAGAAGGTGGAGCTTGCAGGGAGCCCAGATCAT GCCACTGCATTCCAGCATGGGCAACAGAGCGAGACTCCATCTCAAAAAACAAACCAAAAA AAAAGAAATTATTTTCTGACATTTATCAGAACATACTTTATAATCATGTGCCAAGTAGAT AACATCTGCATAGTGCAATTCTGCTAATTTGCAGGATTAATTTTGAAGCCAGTGTAGAAT AGTGCAAAACAAAATAAGGCTTAGAAGGCATTAGGAATCTACTTGAGTTCTGAAGTTAAG TTTGTCTAAAAACTAAATGATTTCTCCACATTCATTTATGAGCAACTGTATGATTCTGTG TATATCTAGATGTACAAAAGCTCTAACTGGATTCGAGGAGAAAGAGTTTAAACTGTAGTC TTAGTCTTACTCAACTTGGAACTTGAAAAGATAATTCCTGGGACTCTGAAAGTATTGGCA TATTTTGATTATCCAGTATAGATCTGAAGGAACATTTCAGGAGTTGGATAAACATGAGAA ATAGGACACCTGTAAAACTATAATAACAACAATTTGGTTGAGTAGTATTTTAATAAGTGG ACATTTTTTTTTCACAAATAGAACTCTTTGAGTCCATTTATGGCTGCCATGTTTGCAGCC ACATAGGTATCAAATAATAATGATGTATTCCAAGGTCACAACTGTGGATGTGGAAGAGAT AGCAAAGGCCTCACCAGTTAGGTAGAAGCAGCAGCTGCATAGTGGTAACAGCAATGAGTG GATGTCAAAAGATAAGTCTGTATTTGGTTCTGTCACTTACTAGCTATGGGAACTTGGAAA AAAATCGTTTAATCTAATCAAATACCAGTAACTTTGTTTATAAAAATAGCGCTCATATCT ACCTCTTAGTTGCATGTGATGAAATAATGTTGTAACAAATGTGAAAACATTTTTTAAACT GGAAAGTCTGTATACAAATGTAAGACAAAATGATTAAAGTGGCATATATGTGAAAGCAGT ATTGTTAGCACAAGAATGGGGAGTAAGAACAGGCATGTGGATTTCTAATTTTGGGTAAGG GGATGGTAACTTTCAGCAGGCTACTACTGCAGATTTTCCATATATAGCAGTTTGGAAAGT GAGACTTTCCTGATGAGATTTTCAATGTTTTGACCTGGAGTAATTTCTTTTTGAGTACCA ACTGTGTGCTAGGCAGTGAGTCTCTGAATATCCAAGATGAAAGATTATGCTGCAGTAGTA GGAAGAGAATAACAAATGAAAAACACTTATAAATTACTGTAACTTTTTCTTTAAAACAAA ACAGAGAATGTTCCTTAAGAGAAAATTGAAGAACTTTATAATTAGCACGCGTATGGGAGT GGCAGTGGAATTCCATGGTCAGAGTAGATCTTTCTGCAACTGCCATTTAATCTCCCATCT CAAAGATGAGGAGTAAGCCATATGAAAGTCTAGGAGGAAGACATTCTGAACAGAGAGGGC AGTGGACCATATTTGTTCATCATTTTGTTCTTAACAACCTCGAATGACTAGCATGCAGAA AGTGGGGTAACCACCAATGTCATCGTCATCCTCATTTTTCTAAGGTGAAGAAAAGTCTGC AAATATGTGTCTGGCATATGTTAGATGTTTCACGAATACATGTTTTTATTTTTCTCTTTA TATGAAGGCTTGCTCTACTTTTCTGAAGTTATGCCTTAAGAACGAATTGCATACTTTATC TAATGATTGTTTGCTTTCATTTAAAAATTACATAAATATAAATTTTCCTTATGAATCTTT CCTTTTATTCAAGCAGTTCTGTATCAGCAAAAAAGATGTAAAATTATTTTCATTATTTTA AGCCCTTGTTTTCCTAAATGAAACAGCTTTTAACAGAGTTCTGTTCCTACTTCGCACGAC ATACTCTGAAAATTCTCTTCATGCCATGCATAGTTTTTAACCAAAAAAACTATAATTATG CATATGTCAAATGTTTAATCATATTGTATTTTGTTTGAAATGTCCTATTGTTTTTGGTGA GGACTACAGTGTAAGGCAGATACTTTGAAGTAAATTCCTTTTAAAATATGCACGAGTGAA TTTTTTTGTGAGTATGATTTATTTTCCTTGCTCAGTAACCTAGTCAATAGCCACATGAAA ATAAAAGATAAGCTTGATCTACAGAGCATATTTGAGGTTTTCTCTTGAAATGTTTTGGTT TTCAATATGTGAACAGCCTTAAATCTAATTGCCTTTAAAGTTAAAAAATGTGTTTTAAAA AAGATTTTTAATAAAAAATGTGATGCTTGTCATTATTATTTTTAAATTGAAATTATTTAT TGAGGCAGGCTGTGGTGGCTCACACCTGTAATCCCAATATTTTCGGAGGGCGAGGTGGGC AGATCACTTGAAGTCAGGAGTTTGAGACCAGCCTAGCCAACATGGTGAAACCCTGTCTCT ATTAAAAATACAAAAATTTAGCCAGGTGTGGTAGCTCATGCCTGTAGTCCCAGCTACTCG GGACACTGAGGCAGGATAATTACTTGGTCTTTGGAGCCAGAGGTTGCAATGAGCCAAGAT CATGCCACTGGGCAACCCTGCGAGGCTTCATCTCAGAAAAACAAAATTAAAAAATAGTAA AAAAAGAAATTATTTATTAATATTATCTTTAACAGATTATCTCTGTGAGTGATACACAGA ATTATGAGTGTTTACCTGAGGCTACATATCAAAAAGAAATAAAGACAACAAATGGCAAAA TAGAAGGTAAGAACCATTTTTTATTTAAAACATCTTTTGTCCAAATGTTTGTCTCAAAGC ATGAGGACTGATATACTCTGACAGCCAGAGAAAATTATTTTTTAAATGCATAACATGGAA GAACAAAGGCAGTGAAAGTTATGTGTCTTCTCAGATGTTGGCAACAGATTATATTGAGAG TGCCAAAAAAGAGCTGAATTATTAGTTTAAATTCAACATACTCTAAGACCTGAGGAAAGG AGTAAAACAGGGAATGAAGACTGAGGAAGACAGAGAGTACAGGGAGTACATGAGGGAACA AGAAGCAGGTTTACATAATGGAGAATGGTAAAATAAAAGAACTCTTTAGAGAAAGATAGA GCATGGTTAGAAAGCTGGGAAGAATATAAAGTGACCTCCCATTACCAAAATTTGGCAGAG AATTACAGCAAACATGTTGACAGTCTTGTCTTTCTCACTGGTGGGAAGGCATTAGGGATG GAAGCACCTGACCATGGAGAGTTGTGTTTTATCTGCAGTATGTGAATATAAGCATATTTT CACAGCTGTGCGTGTATATAATTTGTCATATACACTCAGTATAGACGAGAAGTTTTCACA CTTTAGAAAATCAGCTGAATACCTTGTTAACAATGCACGCTGTGACTCAGCAGACTTGGG ATTCTGGCATTTTTAATAAATTCTCAAGTGATGCTGTTGCTGGTTGTCCTTGGACCTCAC TCTTAAGTAGCAAGGGAACAGCCTTTCCTTTGGAAAAATCTGGAAGAAGGGCAGTTGGAT AGAAGTTCAAGACATAACAGGGTCAAGAGAAAGCATTATATTGCTTTTATTTCTGAGTAT GTTTCTGACCAGAGGGGAAAAAAGAGGTAAAGAAATAGTAATTACAGATGTCAGATACTA CCCTAATCAAAGAGAAAGAAAGTGTTAGGAAAATTGATTTTAAAAGATATTGAATGGGAA GAATCAAGACCACAGATGTGGACATTATTTTGGCTAAGGAAGAGGGATTGTGAGGCATGA AATGCAGCAAGAAAGAAGATAGCCAGCCAACTTTGGAGTTTCTGAAAGGAAATTTGAGTG AATTCACTTCAGATGCATTTACAATATTTGCACTCCAGAAGATTAGATTGTGGGTACTCC AGAGACTACCGGAAGCGGGAGGATTACTAGAATTGGAGTAAACCATGGTGACTCATTAGT TTTCTCTATTACTATCAGGCATAAAATGTTTATATTTTGTTGATATTAGCTATTCAAATG AGAGATATTTGAATCTAAGAGCATTAGCTTTATTTTTAATGAAGCAAATTGTTTTGGTAA AATTGTTGTTCTATAAAAATCTATTAGACACTTACCATAATAAACAAAGCCAACTAATTT TTAGAAACAAAAAATTACAGAATTTATTACTTGAATTCTAAAATTGTTTTTTAAAATAAA TATTGTCTGATTTAAAAATATAAAATGTTATTTATATGTGATAAGTATGTTGCCATAAAT TTTCAAATAAACATATCAATATTGAAAGCTCATTATGCAATATTTTTTAATGAGTTTTAT AGTATTTTTTGCATGAGTGAATCAAGAAAATTTCTGAGGATAAACTAGAGGATACAGCAA TGTAGGCATATGATTACACTGCAAGGATATGGGAAACAATGAATATTTTATTTAGTATTA TCCATTAAGTAAATATCCAAGCTGATCAATTTGTAACATGTTCAGTGATGAGATGTCAGT TCTGCATTCAGCTGAACTCTCATCATAACGGTGTACCATCTCAATTGTAGGACAAATTAA AGAACATGATTAATGTAATGATATAAATTATTCCAGTGTATTTCACTGAATATATGGCGT AGGATTCTATATTCAGCTTTGACATTTATTTTTTCTGGGTCATAATTTGCTCCTCTGATC AAAGATCATTTCTCTTTTCATCACTCAGCATATACATATTAATATCAACACATTTTGCAT GCACAACACATTCTCACTTTTGAAGTCTTAAGTGCATGTTTGATGAAGCCTAGATTCCTA GTTTCTTCAGTGTATTTCTGTCATGTGATTGTCCTAAAGAAACATACCGAAAGAAAACCC CCTAAACCTAAAGGAATCATTCTCAAAGCTGAGAAAAAGGACTTAGATACTATCACTGGA TTCATTTGTGGCTGGTTTTGTCATATTTACTTATGACTGATAATAAATCTCTTTTGCTTT TTAGAGTCTCCTGAAAAGCCTTCTCACTTTGAGGTATTGAGTTTTATAATTTTATCTTGC ATTATTTATTAACTATGTATTTTGTGAAGTACACATTCGTTATTAATCATTTTTCTTCCA AACCCGTTTAGCCTGCCACTGAAATGCAAAACTCTGTTCCAAATAAAGGCTTAGAATGGA AGAATAAACAAACATTGAGAGCAGGTAAATTTTACAGTTCAACTATATTAAAATGAATAT TTCAATAGTTGACATATTAATAGTCTCATCTCCCCAATGTTTATTTTTCAAATATTATGG AAATATTTGAGTTAATAATGTCAATAGTGGTATCCACATTTGAAAAACTGATTACTTACA AGAACACGAATTTTAATTAGTTTTTTTAAAAAGTAGCTTTAATTTCAGGTGTTTCCACTT TCACGTCCTCATACTGTAATGTTTTGTATTGGGAATGTCTGTATGACTTAAAGATTCAAG AAGGTGTATTTTTAAACTCTAATATTTTTTTCTGTTCAAAAATTGATTCAAATTCTACCC TTTACTGCAGGGAAAGCTTCAATTTTGACATGCCAATTGTGTTTTAACATTGGTTACCTC ATGGGACTGTAGTCATTTGAAGCATCCTAAGGAAATCTGTTGTTCTGATTAGCTTACTTT CTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGTGTGCACGTTTGTGCCTG TGTGCATGTATATGTGTGTTTGTGTGTGGTACCCTTAATTTTTAAAAACTGGGAGAAGTA AGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCTGGAGGCGGAGCTT GCAGTGAGCCGAGATGGCGCCACTGCACTCCAGCCTAGGGGACAGAGCGAGACTCCGTCT CAAAAACAAACAAACAAACAGAAATAATAATAATAATAAATGGGAGAAGTAATCATTTCT TTATGATCATTTTGGTAAAACTGTGATTCTGAAGCATTTGGCTTTGTGTCTTTTCATTGT TTAGAGGTAAACAATTGTCTAAACTGGTTTTTTATATTATTCCTATGCATGCTTAAAAAT TATACAACATATGTGCACGGTCATAGATAATATGTAGAATTTGTTTTCAACTGCTAATAT GTAAATAATTGTACATTGTGTAATTTTCTGTAACATTCTTTGTTTGATCAGCATTATATT GTTAGATCCATCCATAATGTGTAGAATTAACTTTGGTTTTGTTTATATTAGGTTCTTTAT AGAATTCCATTATATAACTGCACCACAACTAATTAAAATTTGTTTATGCAAAAAACAAAT ATATGAAAATAAAAACAAATGAGATATCAGTCTTCATTTAAGTTGGTTTTTACCTACTGA TTTTTGATATATTAGAAACTGAAACTAAAATATTTCAAGTATCACTATGTACAATCTTCT ACTTTAATAAAAGTGAAAACTGTGACCTATGGACCATTAAAGCTATGCTGTTGTAACACA TTATTTCCCTGAAACAGTGCAGTATAGACTTCATAGTACATATGAACTTCATGGTACATA TATGACACATTTTCTTAATCCAGTCTATCATTGATGGGCATTTGGGTTGGTTCCAAGCCT TTGCTATTGTAAATAGTGCCACAATAAACATATGTGTGCGTGTGTCTTTATAGTAGCATG ATTTATAATCCTTAGGGTATATATCCAGTAATGGGATCGCTGGATCAAATGGTATTTCTA GTTCCAGATCCTTGAAGAATTGCCACACTGTCTTCCACAATGGTTGAGCGAGTTTACACT CCCACCAACAGTGTAAAAGTTTTCCTATTTCTCCACAGCCTCTCCAGCACCTGTTGTTTC CTGACTTTTTAATGATCGCCATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGA TTTGCATTTCTCTGATGGCCAGTGATGATGAGCATTTTTTTCACGTGTCTGTTGGCTGCA TAAATGTCTTCTTTTCAGAAGTGTCTGTTCATATCCTTCACCCACTTTTTGATGGGGTTG TTTGATTTTTTTTTAAAACTTGTTTAAGTTCTTGTACATTCTGGATTTAGCCCTTTGTCA GATGGATAGATTGCAGAAATTTTCTCCCATTCTGTAGGTTGCCTGTTCATTTTGTTCACT CTGATGGTAGTTTCTTTTGCTGTGCTGAAGCTCTTTAGTTTAATTAGGTCCCATTTGTCA ATTTTAGCTTCTGTTGCCATGGCTTTTGATGTTTTAGTTCTGAAGTATTTGCCCATGCCT ATGTCCTGAATGGTATTGCCTAGGATTTCTTCTAGGCTTTTTATGGTTTTAGGTCTAACA TTTAAGTCTTTAATCCATCTTGAGTTAATTTTTGTATAAGGTGTAAGGAAGTGGTCAACT TTCAGTTTTCTGCATATGGCCAGCCAGTTTTCCCAACATCATTTATTAAATAGGGAATTC TTTTCACATTGCTTTTTTTCCAGTTTTGTCAAAGATCAGAGGGTAATTTTCACATTTCAA TGAATTTGTCCATTTTGTCTAAGTTGTCATGTTTATTCACATAAATTTTATAATATTACC TTGTATTTTTAAGTATCTGTAGAATCTAAAATAATGTCACATTAACTCATTTCCAAAGTT AGTAATTGTAGCTTTCTCTTTTCAAGAGCTAGTTTGGCTAGATAGACTTTTGCTTTTATT GATCCTCTCAAAGTGTTTGGTATTTTTCAACTCTTCCATCATTTTTGTGTTTTATTAGTT CCATCTCTGATGTTTTAGTTCTCTTTGCCTAGTATTTAAAAAATCTATAGTTGGGAGCTT ATCAACAACATAAATTGAATTCTCACAATTTTGGAAGCTGCACAGTTCAAGATCAAGTTA TCATCAGATTTGATGTCTGAAGAGGTACCACTTCATGATTCATTGATGCATTCTTTTTCC CTGTGCCCTCACATGGCAGAAAGGGTAAAGAGGCTCTCTGGGGTTATTTCTGTCAGAGCA TTAATCCATTTATGAAGGGTTGGCCCTCATGACCTAATTACATCCAAAAACTCCTACCTC CTAATAACGTCACCTCTGTGATTTGATTTTGGCATATGAAAATTGCAAGGACAAAGACAT TCAAACCAATACGAATATTTATCCTTTCCTCTGCTTCCATTGGATTTACTTTCTTATTTT TTTTTTTTTTTAGCTTCTTCAGGTAAAAGTCGAAGTTATTTACTTGAGAGTCTTCTAATG TAGACATTCAATGCTGAAAAGCTTTATTTAAGTGCTGTTGTAGATGCATTTTACAATATC TAATGTGCTGTGTTTTCATTTGAAGTTAGTTCAAAATACTTTCTAATTTTTCTTTTTACT ATTTTTGGAACCAACCCAGGGTTATTTGGATGTTATGTTACTTAATTTCCAATAGTTGTG TTGTTTCAGGTACATTTTTATTATTGATTTTTAATTTGATTGCTTTTGGGTCAGGTAACA TGTTTTGTATGACTTAAATCCTTCTTAATCCTTTTACTAAGATATAATCTAGAATATAGT CCTTGAGTACTTCTGAAGAATGGTGTTAAGTCTACCATATTCTTGCTGATTTTCTGCCTC CTTATTCTACCACTTGAGCAAGGGGTTTAGAAATTTTAGACTATACTTAGGCATTTGTCC ATTTCTTTTGCAGTTCTATCTATTTTTGTATCATGTATTTTGAAGCATTTATGTTATTAT CTACATAAATATTTAGGACTGTTATGTTTTCTTGATTAAGTGAACCCTTTGTCACTATAA AATCACCTTGTTTATTGCTGGTAATGTTTTTGCTGTGAAATGTACTTTGGTATTAATACA ACCACTCTTCCTCAGCCTTCTTTTTTCAAGTGTTAGTGTGGTATATCTTGTTTCATCTTT AACCAATTTTTGTCTTTATATTTAAAGTTTATTTCTTATAGGTGTTATACAGGTAGATCT CACTTGTATATCCGTTCTGACAATCTGCCTTTGAGCAGAGGTTTTTAGACCAGTTTAATT TATAATGTAATTATTGATGTGATAAAAGTTGTCTGTCACCATGCTGTTTGATTTCTGTTA GTCCCAGATCTTCTTTGCTCTGTTTTGTTCTTTTATTGCTTCCTTCAGACTAGTTTAGTA ATTTTTATGATTTAGTTTTATATATATATATATATATATATATATATATATATATATATA TGTATAATGTTTTTTAGTTATTGATCTGGTTGTATATTTCTTCATGATTTAGTCATATCT TTTTGTGGTATAAGTTTATTTGGCTATTAGGTATAACTCTTTGCTTTGCTGTCTTAGTGG TTGTTTTAGGATTTATAGTGTATGGATTTACCTCATCACAACTCACCTTCAAGTAATATT ATATCATATCATAGATGGTATAAGAAATTCCAATCATATATTTTCATTTCTTCACTTCCA GCCAGATACCAGCCTGGATCTGTGGGATTGTAGCATTTGTTAAGTTTAGAATATATTTAG CCAATTTTTCTTCAGATGTTTTTTCTGTCTCTCCTTCTACCTCTTTGTGGACTTACATAT TACCTGCTGGGAGTTTGCTCATAGTTCTCTAGTATCTCAAATTTGTGAATCTTTTCTTGC ATAGATGATGGCAAATCAATCTATGCTCATATCTACTCAGTGTAGCTTTCATCTGCAGCA TTGTAACTTGTATCTCTAGAAGTGCAATTTAGTTTTTAAAAGTATCTTCTATTGCTTTAC TTATCTTCTTGATTTTTATTGTAGAATAGAGTTGAGTTACTTATAAACAGCTTGATCCTT TTCATTTTTGCTTTTTATGAGCTGACTCCCCACACCTGAGGCAAGGCCTTTCAGACTATT CATTTTCCTGTGAAGTCTGAGTCTTCCCAGGCAAATCTATAAAAATAGACACTCTTCTTG GCACTATGTGAGCACCAGGTGTGATTTTCTCTAATTTTATAAGTTCCGCCCTGACCTGGC TTGGTCTTAGGTAGTTTTCTGGCTTACATGCAATCTTCATTATTTTGCTAAATACTGGGA GGCAATTTCCAGGGGTTTCTTGCTTTTGCTTCTGTATCTCTGTCTCCTCTTCAGTGTTCT GTTCTATATTGTCTGTCTCCTTTGGTTTTACCAGACTCTAAGATTTATCACTGTAACCAA GAGAGTCTGGTAGGTTCCACCTCAGTTTTTGTTTCCTGTGTCAGGTCTTGGAATTTCTGT CAAGGCAAGAAGCTGAAACATTCATAAGGTTTGCTTTCCACTTTTTTTTTCTGTTTTTCA GGGACTATCATCTTCTTTGCCTAATGTCCACTGTCTAAAAAATTGTTTAGTGTATTTTGT GTGTTTTATTTTTAGTTATTTTAGCTAAGAAGAAAAATCAATACCTGTTGTTCTCTCTTG GCTGGAGGCAGACTACACTAGAGCTTCAGCACATGCCACACACTGGCTAAAATGCTTTTC TTCCCCCCTTGCTCAACTGCTTCCTTTTCAATCTTTGTTCCTCAGTGTAGCCATACATTC CTCGGGGGAATTTTCCGTGGGCCTAGTACAGATCCTATTCTTAGCAATCTATTTTCTTAC AGTATCTATCTGAATTTATAATTGTAACTTTTCTGGGGCTTTGCTTTTCAGTATATTTTA AGCTAAACAAGAGCAGAGTTTTTTTTTTTCTGTTTAATCTGCAGAGCTTAGTATAATGCC TTCCACATGGTAGGCAATCAATATATATTTGTTGAGTGTATGAGTTAGTGATTGTTAAAA TATGCAGCCCTTTATATCCCAAAAGTACTAATATATTTTATTTCTATCTCCTCCTTGAGA CAGATTCAACTACCCTATCAAAAATCTTGGATGCACTTCCTTCTTGTGAAAGAGGAAGGG AACTTAAAAAAGATAACTGTGAACAAATTACAGCAAAAATGGAACAAACGAAAAATAAGT TTTGTGTACTACAAAAGGAACTGTCAGAAGCGAAAGAAATAAAATCACAGTTAGAGAACC AAAAAGCTAAATGGGAACAAGAGCTCTGCAGTGTGAGGTATGACATCCTAGTTTTAAATA AATATTTCAACTATTTATACTAAAAGTATGTAGGATACTTTTTGTAAAAGCTGACTTACC TTCTGAGATTTAACTGGAGAAAAAAATCTGTCTTGTAGAGTGTCAAATTCTTTTAAATAA TAAAAGTTCTTAAATGTGAATACTTCCACTGATAATTAATGCATATTTATTTAAATCACA ATTTTAATGGCTATATAGAAGGCCATTATTTGGAAATACCATTACTTAGCAAATTAATTT TTTTGATTTTTAATTTTTTGTATTATAAATGCTACAAGACATAACTGCATGTAAATCTTT TTCTACCTTTCTAATTATTGACTTGGAATAAATTCTTCAATATAGAAATATTTAGTTAAA TTATAGGAATTTTTAAAAAGTTCTTTGTTCATTACTTCTAAATTGTTCTCAAGAAAATTT ATATTCATTTACAGTTCAACAAAGACAGTGTGAAACGGCCATTCTTCTCTCTCCAAGAAT CAATTTCCTTTAACTATACACTTTTAATCTTAATGTGCATGGAATATAAAGAAAATATAA TTTATGATTAGTTTATTCAACATCTCTCGCTCTCCTACATAAATAAAATTAATTCAGAGT TCTAGGTTAAAAATACATATTATTTTTAGTCTTTAATTAAATATTTATACTTTTTCTTGT TCTAAAGGAGATTTAAAATTTGTTGAAAAATATATAATACTCAACAAGATATGTTTAACT CTTACTCAAAAAAGAAACAAAAGGCATATGGGATGACACATATTAGACTCTTTAATCTAG TCTGAGATCATAATATTCAAATTATTTTTAGGGATATTTGCCATATTTTATAAGTAGAAA TATTTATGTCTAATAAATCTGTAAACTTTTTTTATAAAAAGTAATGTCACTTTAATCAGT TAACTCTAAATGATCTGTCCTCACTGAGGACTAATTTTGACTGTGTGATATTTTTAAAAA ATAATTTTCAACTTATAAATTTACTAGATAGCTTCCAATATTCTTTTCCATAACAGTTGT CAAAGTTACTAGTAACAGAAACTTTCTAACTAGAAGAAGTTTTTTCTCACTATTTTTCAA GTATGTATGTCATTTGGAAGAGGTTACGGAGTAATGAATACCAGAGAACTAGAAAGAAAA AAAAAATTCAGGAATATAGGAATTTTATTGGAATAATAAACCAGTATAGGAAGAAGTAGA TCTCAAAGTGAATTCTATTTTCTAACAAAATGAATTTTAAGATAAGTATGTTTAATGGCA GATTGACTTTAAATCAAGAAGAAGAGAAGAGAAGAAATGTCGATATATTAAAAGAAAAAA TTAGACCCGAAGAGCAACTTAGGAAAAAGTTAGAAGTGAAACAACAACTTGAACAGACTC TCAGAATACAAGATATAGAATTGAAAAGTGTAACAAGTAATTTGAATCAGGTAAATCAAT CTCTGGCAAAAATTTTATATTTCTGACTTTATTTCATCAGTATTACTTTTAACATCCCTT TGATTTAGTATGTGTTATTCAGGTCTAAATCAAAGAAAAGTATTGTCTTAAAATTAACTA TGACTTTTGTAGCTACAGGTATTTATTATAAATTATGGCATGCAAATAGTATCTTATTTC AGTACAAAGAGCTTTTGAAAATAATGATAATCCCTACCATATACTTAGTGATAATTTATT GGTAAGTATTTTATTCCTAGCAACATAGATTAGTGTATTTTTCCTAGTTAACATTTAATA CTGACTCAAACATTATCAAGAGGAAGCAAAAGTTAGTGTCGTAGTAAATAAGCTCATGGT TTTCTAAGTAGGGCTCTCTAGATTTTATCTTCTTTACCACTTTTGTTTTGAAATAGAAGA CTTCTTTTATATTTACGTATTTACCCAGTAGAATTAACTGAGATTTGGTGGAGAAGTCCT GGATGTAGACTCAGAAGACTTGGAGAAAATCCTACAACTTGATTATATTTTTAATCTTTT CCTTTCAGAATTGTGATAACTAAAAGTGCTTGTTACAATGTCTCAACTTATCAAACATTC ATAAATATAATTCTTACAATTAACTATATTTTTTAGAAACACAGAATATCTAGAGAATAT TCTCAGGAAAAAGGAACTGAAAGAGCTTCCAGAAATTTTATCTGTCTAAATATATGTAGC ACTAAGGCTCTTAGTATGGGATGTTGTATAGGTTAGACATCAGAGTGTAAACCCAATTTT TGTATGTAGTCAAATTGATTAATCTTTTATTTTATGCTTTTGAGCTTGTTGTAATTCAGG GAAAGTTTTTTTTTTTTTTCAATTCTGAGGCTCTTAAAAATTCTCTAGTCGTTTCTCTTT TACTTTCATGAATTCGTTGTCTCCAAATAAATGTTTGAACTTTGGGGAATTTATGCTCTA TAGTATTTGAAGTTTTGATTCAATGGTTCTTCAACTGATACCTACTTATAAAAACCCTTT CATTGTATAAACGTACAAGTTGTTCTTTAATTTCAGAGGAACTATGATATGCCATTTTAT TGAGTGCTAGTTAAATTTTTATTTTGTTTTATTTAGGTTTCTCACACTCATGAAAGTGAA AATGATCTCTTTCATGAAAATTGCATGTTGAAAAAGGAAATTGCCATGCTAAAACTGGAA GTAGCCACACTGAAACATCAACACCAGGTGAAGGAAAATAAATACTTTGAGGACATTAAG ATTTTACAAGAAAAGAATGCTGAACTTCAAATGACCCTAAAACTGAAACAGAAAACAGTA ACAAAAAGGGCATCTCAGTATAGAGAGCAGCTTAAAGTTCTGACGGCAGAGAACACGATG CTGACTTCTAAATTGAAGGAAAAACAAGACAAAGAAATACTGGAGACAGAAATTGAATCA CACCATCCTAGACTGGCTTCTGCTTTACAAGACCATGATCAAAGTGTCACATCAAGAAAA AACCAAGAACTTGCTTTCCACAGTGCAGGAGATGCTCCTTTGCAAGGAATAATGAATGTT GATGTGAGTAATACAATATATAACAATGAGGTGCTCCATCAACCACTTTATGAAGCTCAA AGGAAATCCAAAAGCCCAAAAATTAATCTCAATTATGCAGGAGATGATCTAAGAGAAAAT GCATTGGTTTCAGAACATGCACAAAGAGACCGATGTGAAACACAGTGTCAAATGAAGAAA GCTGAACACATGTATCAAAATGAACAAGATAATGTGGACAAACACACTGAACAGCAGGAG TCTCTGGAGCAGAAATTATTTCAACTAGAAAGCAAAAATAGGTGGCTTCGACAGCAATTA GTTTATGCACATAAGAAAGTTAACAAAAGCAAGGTAACAATTAATATTCAGTTTCCTGAG ATGAAAATGCAACGTCATCTAAACGAGAAAAATGAGGAGGTATTCAATTATGGTAACCAT TTAAAAGAACGTATAGATCAATATGAAAAAGAGAAAGCAGAAAGAGAAGTAAGTATCAAA AAATATAAATACTTTTCAAACTTCCTGAAAGAAAGTGGCCTTGGCTAAATGCTGAATCTA GTTGAATATATATATATATAAATAGATGATAAATGTACTTACTATATCAGCTTAGAAACA TGCCTCATTTCCACCAAATGAAAGTGAAAGCTAAGAGACGTTTTACTTTGAGTAAAGGTA TTGTGTCACTGATGAAATTATAAGAGTTTAAGTTAAAGATTTTTAATAGATTAACATTAA TGACATTGGCTTATACTGCTGAAATAAAGGTTTTAATGTCTCTTTGTGGCCACATTTTTT GACTACAATGAAGCAGAAAAATGGGAATGCCCATATCAGCAATTAGTATTTTGAAATTAA GATTCAGTTCAGCAATTTACATTGACAGTTAATTCTAAATTTTCCAGAGGAACAGAAGTG TATTTGAAGTATATTTTGAAGTGTACATTTCTGCATCTTGTAATAACACTTTTTAAGTAG CTTTTTATATATTTTATTTGGTAGAATTTTATTTTCATTTATGTCAATTTGACTTAATCT GAACATATTTGAATCTGAAATTATGTATTGTTAAAACCTCTCAATTTTTTAAAGGCATCT GTGTTTTGTTAAATAATACCTTAGGACAAATGTAGTGGATTTTAGCAATATCAAATTTGA TTTAATCACCCCACTGGTATTCATAATTTATTTTGAATATTGTTACAAATCATTTGCTCA TAATTTCTATTTCAAGGCTCAAAAACTATCATGTGGATAGAACTTTGTCCCACAGAAAGA TGATTGTAGCTATCTGTGATTTATTAGCTTTGCATTGGATCCCCATTTTTCAATTCATAA GGGGTGGCAAGGTTCATGTATAGTACAAAAGAAGTGAGTAGAGGAGAGAAACATAGGAGC TGAGGTCAGGAGGGATGTGGAGACCAGGTTACCAAGGGCCTGTAAAGTTTGAAATAAAAT TACTTTTATTCTGAGATAAAAATCTATTGGAAAAATTTCAGCAGGTGATTGAATATGTGA GGAACTTTGATGTTGATTTGTGCTTCTAATACAGAAGAAGGAAAGAATTCCACTGTTTAG AATTTACCACCACTAGTCCTGCCTTTTTTTTTTTTTTGAGACTTCAGTAAGTTGTGAAGA ATTACAGATTCATTAAGGGAAGAAATTACCAGTGAGATGAATCTTGTGTCTAGTAAGACA GTACCAATTTGGCAGAAAGATTACACCTTCTTGTGTCCTTAAGTAAATTCACTAACAAGC AGCAGTGTGCACAAATGAAGAAAATAAACTGAATCAATATATTTGGGGATCTTTTTGAAA GTAAATATTGTTAATTTGATAAGATGATTCACAAAATCAAAAACATGTCTTTTCAGGTCA TTGTGAGACAACTTCAAAAAAAATTGGCGGATCTTAATAAACAGTGTGAGGCTTCACTAA AGGTTACATCACATTCTCACTCTCTGAGGCATCAATAGAGGCTACATCACATTATCACAT TAATCTCAAAGGTGAGATACAGGATTTAATGAGGAAATGATTTCAAATCAAAAGTCAAGT GTGTGTTAAATGTAACATGCCAACAGTGAGTCTATAACTGGTTAAA bcftools-1.21/test/csq/ENST00000580206/ENST00000580206.fa.fai000066400000000000000000000000231467060157400215240ustar00rootroot0000000000000018 125866 25 60 61 bcftools-1.21/test/csq/ENST00000580206/ENST00000580206.gff000066400000000000000000001077111467060157400211560ustar00rootroot0000000000000018 Ensembl chromosome -14728171 65645113 . . . ID=chromosome:18;Alias=CM000680.2,chr18,NC_000018.10 18 ensembl_havana gene 100 125866 . + . ID=gene:ENSG00000180777;Name=ANKRD30B;biotype=protein_coding;description=ankyrin repeat domain 30B [Source:HGNC Symbol%3BAcc:HGNC:24165];gene_id=ENSG00000180777;logic_name=ensembl_havana_gene_homo_sapiens;version=14 18 havana lnc_RNA 100 80559 . + . ID=transcript:ENST00000579292;Parent=gene:ENSG00000180777;Name=ANKRD30B-203;biotype=processed_transcript;transcript_id=ENST00000579292;transcript_support_level=5;version=5 18 havana exon 100 342 . + . Parent=transcript:ENST00000579292;Name=ENSE00002725437;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002725437;rank=1;version=1 18 havana exon 69489 69517 . + . Parent=transcript:ENST00000579292;Name=ENSE00003643498;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003643498;rank=2;version=1 18 havana exon 69610 69682 . + . Parent=transcript:ENST00000579292;Name=ENSE00003622033;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003622033;rank=3;version=1 18 havana exon 80379 80407 . + . Parent=transcript:ENST00000579292;Name=ENSE00003561355;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003561355;rank=4;version=1 18 havana exon 80500 80559 . + . Parent=transcript:ENST00000579292;Name=ENSE00002730393;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002730393;rank=5;version=1 18 ensembl mRNA 20068 124566 . + . ID=transcript:ENST00000358984;Parent=gene:ENSG00000180777;Name=ANKRD30B-202;biotype=protein_coding;tag=basic;transcript_id=ENST00000358984;transcript_support_level=1 (assigned to previous version 8);version=9 18 ensembl five_prime_UTR 20068 20247 . + . Parent=transcript:ENST00000358984 18 ensembl exon 20068 20468 . + . Parent=transcript:ENST00000358984;Name=ENSE00002240376;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00002240376;rank=1;version=1 18 ensembl CDS 20248 20468 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 24394 24508 . + . Parent=transcript:ENST00000358984;Name=ENSE00001626627;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001626627;rank=2;version=1 18 ensembl CDS 24394 24508 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 24667 24840 . + . Parent=transcript:ENST00000358984;Name=ENSE00001676471;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001676471;rank=3;version=1 18 ensembl CDS 24667 24840 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 26727 26833 . + . Parent=transcript:ENST00000358984;Name=ENSE00001619132;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001619132;rank=4;version=1 18 ensembl CDS 26727 26833 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 29643 29780 . + . Parent=transcript:ENST00000358984;Name=ENSE00001745513;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001745513;rank=5;version=1 18 ensembl CDS 29643 29780 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 32382 32446 . + . Parent=transcript:ENST00000358984;Name=ENSE00001775164;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001775164;rank=6;version=1 18 ensembl CDS 32382 32446 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 35514 35918 . + . Parent=transcript:ENST00000358984;Name=ENSE00001621399;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001621399;rank=7;version=1 18 ensembl CDS 35514 35918 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 41171 41201 . + . Parent=transcript:ENST00000358984;Name=ENSE00001784782;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001784782;rank=8;version=1 18 ensembl CDS 41171 41201 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 43984 44056 . + . Parent=transcript:ENST00000358984;Name=ENSE00001686934;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001686934;rank=9;version=1 18 ensembl CDS 43984 44056 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 49813 49903 . + . Parent=transcript:ENST00000358984;Name=ENSE00001743456;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001743456;rank=10;version=1 18 ensembl CDS 49813 49903 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 51788 51849 . + . Parent=transcript:ENST00000358984;Name=ENSE00001672877;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001672877;rank=11;version=1 18 ensembl CDS 51788 51849 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 54355 54442 . + . Parent=transcript:ENST00000358984;Name=ENSE00001723800;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001723800;rank=12;version=1 18 ensembl CDS 54355 54442 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 56164 56192 . + . Parent=transcript:ENST00000358984;Name=ENSE00001669710;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001669710;rank=13;version=1 18 ensembl CDS 56164 56192 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 56291 56363 . + . Parent=transcript:ENST00000358984;Name=ENSE00001606157;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001606157;rank=14;version=1 18 ensembl CDS 56291 56363 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 58867 58928 . + . Parent=transcript:ENST00000358984;Name=ENSE00001736208;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001736208;rank=15;version=1 18 ensembl CDS 58867 58928 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 63229 63319 . + . Parent=transcript:ENST00000358984;Name=ENSE00001785342;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001785342;rank=16;version=1 18 ensembl CDS 63229 63319 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 68049 68077 . + . Parent=transcript:ENST00000358984;Name=ENSE00001629126;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001629126;rank=17;version=1 18 ensembl CDS 68049 68077 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 68171 68243 . + . Parent=transcript:ENST00000358984;Name=ENSE00003619909;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003619909;rank=18;version=1 18 ensembl CDS 68171 68243 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 69489 69517 . + . Parent=transcript:ENST00000358984;Name=ENSE00003534627;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003534627;rank=19;version=1 18 ensembl CDS 69489 69517 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 69610 69682 . + . Parent=transcript:ENST00000358984;Name=ENSE00003491240;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003491240;rank=20;version=1 18 ensembl CDS 69610 69682 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 70929 70957 . + . Parent=transcript:ENST00000358984;Name=ENSE00003507996;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003507996;rank=21;version=1 18 ensembl CDS 70929 70957 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 71051 71123 . + . Parent=transcript:ENST00000358984;Name=ENSE00003477650;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003477650;rank=22;version=1 18 ensembl CDS 71051 71123 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 74045 74106 . + . Parent=transcript:ENST00000358984;Name=ENSE00003464535;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003464535;rank=23;version=1 18 ensembl CDS 74045 74106 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 75562 75652 . + . Parent=transcript:ENST00000358984;Name=ENSE00003568491;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003568491;rank=24;version=1 18 ensembl CDS 75562 75652 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 80379 80407 . + . Parent=transcript:ENST00000358984;Name=ENSE00003518163;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003518163;rank=25;version=1 18 ensembl CDS 80379 80407 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 94433 94505 . + . Parent=transcript:ENST00000358984;Name=ENSE00001784236;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001784236;rank=26;version=1 18 ensembl CDS 94433 94505 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 100106 100136 . + . Parent=transcript:ENST00000358984;Name=ENSE00001749792;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001749792;rank=27;version=1 18 ensembl CDS 100106 100136 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 103211 103283 . + . Parent=transcript:ENST00000358984;Name=ENSE00001742133;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001742133;rank=28;version=1 18 ensembl CDS 103211 103283 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 109039 109117 . + . Parent=transcript:ENST00000358984;Name=ENSE00001631899;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001631899;rank=29;version=1 18 ensembl CDS 109039 109117 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 109443 109504 . + . Parent=transcript:ENST00000358984;Name=ENSE00003587900;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003587900;rank=30;version=1 18 ensembl CDS 109443 109504 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 112416 112506 . + . Parent=transcript:ENST00000358984;Name=ENSE00003649247;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003649247;rank=31;version=1 18 ensembl CDS 112416 112506 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 114725 114753 . + . Parent=transcript:ENST00000358984;Name=ENSE00003490819;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003490819;rank=32;version=1 18 ensembl CDS 114725 114753 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 114852 114924 . + . Parent=transcript:ENST00000358984;Name=ENSE00003634416;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003634416;rank=33;version=1 18 ensembl CDS 114852 114924 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 120544 120757 . + . Parent=transcript:ENST00000358984;Name=ENSE00003472095;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003472095;rank=34;version=1 18 ensembl CDS 120544 120757 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 122042 122210 . + . Parent=transcript:ENST00000358984;Name=ENSE00003581729;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003581729;rank=35;version=1 18 ensembl CDS 122042 122210 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl CDS 123337 124308 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 123337 124566 . + . Parent=transcript:ENST00000358984;Name=ENSE00003887179;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003887179;rank=36;version=1 18 ensembl three_prime_UTR 124309 124566 . + . Parent=transcript:ENST00000358984 18 havana mRNA 20068 125866 . + . ID=transcript:ENST00000665241;Parent=gene:ENSG00000180777;Name=ANKRD30B-205;biotype=protein_coding;tag=basic;transcript_id=ENST00000665241;version=1 18 havana five_prime_UTR 20068 20247 . + . Parent=transcript:ENST00000665241 18 havana exon 20068 20468 . + . Parent=transcript:ENST00000665241;Name=ENSE00002240376;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00002240376;rank=1;version=1 18 havana CDS 20248 20468 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 24394 24508 . + . Parent=transcript:ENST00000665241;Name=ENSE00001626627;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001626627;rank=2;version=1 18 havana CDS 24394 24508 . + 1 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 24667 24840 . + . Parent=transcript:ENST00000665241;Name=ENSE00001676471;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001676471;rank=3;version=1 18 havana CDS 24667 24840 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 26727 26833 . + . Parent=transcript:ENST00000665241;Name=ENSE00001619132;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001619132;rank=4;version=1 18 havana CDS 26727 26833 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 29643 29780 . + . Parent=transcript:ENST00000665241;Name=ENSE00001745513;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001745513;rank=5;version=1 18 havana CDS 29643 29780 . + 1 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 32382 32446 . + . Parent=transcript:ENST00000665241;Name=ENSE00001775164;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001775164;rank=6;version=1 18 havana CDS 32382 32446 . + 1 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 35514 35918 . + . Parent=transcript:ENST00000665241;Name=ENSE00001621399;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001621399;rank=7;version=1 18 havana CDS 35514 35918 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 41171 41201 . + . Parent=transcript:ENST00000665241;Name=ENSE00001784782;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001784782;rank=8;version=1 18 havana CDS 41171 41201 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 43984 44056 . + . Parent=transcript:ENST00000665241;Name=ENSE00001686934;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001686934;rank=9;version=1 18 havana CDS 43984 44056 . + 1 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 49813 49903 . + . Parent=transcript:ENST00000665241;Name=ENSE00001743456;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001743456;rank=10;version=1 18 havana CDS 49813 49903 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 51788 51849 . + . Parent=transcript:ENST00000665241;Name=ENSE00001672877;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001672877;rank=11;version=1 18 havana CDS 51788 51849 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 54355 54442 . + . Parent=transcript:ENST00000665241;Name=ENSE00001723800;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001723800;rank=12;version=1 18 havana CDS 54355 54442 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 56164 56192 . + . Parent=transcript:ENST00000665241;Name=ENSE00001669710;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001669710;rank=13;version=1 18 havana CDS 56164 56192 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 56291 56363 . + . Parent=transcript:ENST00000665241;Name=ENSE00001606157;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001606157;rank=14;version=1 18 havana CDS 56291 56363 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 58867 58928 . + . Parent=transcript:ENST00000665241;Name=ENSE00001736208;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001736208;rank=15;version=1 18 havana CDS 58867 58928 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 63229 63319 . + . Parent=transcript:ENST00000665241;Name=ENSE00001785342;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001785342;rank=16;version=1 18 havana CDS 63229 63319 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 68049 68077 . + . Parent=transcript:ENST00000665241;Name=ENSE00001629126;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001629126;rank=17;version=1 18 havana CDS 68049 68077 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 68171 68243 . + . Parent=transcript:ENST00000665241;Name=ENSE00003619909;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003619909;rank=18;version=1 18 havana CDS 68171 68243 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 69489 69517 . + . Parent=transcript:ENST00000665241;Name=ENSE00003534627;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003534627;rank=19;version=1 18 havana CDS 69489 69517 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 69610 69682 . + . Parent=transcript:ENST00000665241;Name=ENSE00003491240;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003491240;rank=20;version=1 18 havana CDS 69610 69682 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 70929 70957 . + . Parent=transcript:ENST00000665241;Name=ENSE00003507996;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003507996;rank=21;version=1 18 havana CDS 70929 70957 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 71051 71123 . + . Parent=transcript:ENST00000665241;Name=ENSE00003477650;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003477650;rank=22;version=1 18 havana CDS 71051 71123 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 74045 74106 . + . Parent=transcript:ENST00000665241;Name=ENSE00003464535;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003464535;rank=23;version=1 18 havana CDS 74045 74106 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 75562 75652 . + . Parent=transcript:ENST00000665241;Name=ENSE00003568491;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003568491;rank=24;version=1 18 havana CDS 75562 75652 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 80379 80407 . + . Parent=transcript:ENST00000665241;Name=ENSE00003518163;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003518163;rank=25;version=1 18 havana CDS 80379 80407 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 94433 94505 . + . Parent=transcript:ENST00000665241;Name=ENSE00001784236;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001784236;rank=26;version=1 18 havana CDS 94433 94505 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 100106 100136 . + . Parent=transcript:ENST00000665241;Name=ENSE00001749792;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001749792;rank=27;version=1 18 havana CDS 100106 100136 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 103211 103283 . + . Parent=transcript:ENST00000665241;Name=ENSE00001742133;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001742133;rank=28;version=1 18 havana CDS 103211 103283 . + 1 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 109039 109117 . + . Parent=transcript:ENST00000665241;Name=ENSE00001631899;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001631899;rank=29;version=1 18 havana CDS 109039 109117 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 109443 109504 . + . Parent=transcript:ENST00000665241;Name=ENSE00003587900;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003587900;rank=30;version=1 18 havana CDS 109443 109504 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 112416 112506 . + . Parent=transcript:ENST00000665241;Name=ENSE00003649247;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003649247;rank=31;version=1 18 havana CDS 112416 112506 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 114725 114753 . + . Parent=transcript:ENST00000665241;Name=ENSE00003490819;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003490819;rank=32;version=1 18 havana CDS 114725 114753 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 114852 114924 . + . Parent=transcript:ENST00000665241;Name=ENSE00003634416;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003634416;rank=33;version=1 18 havana CDS 114852 114924 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 120544 120757 . + . Parent=transcript:ENST00000665241;Name=ENSE00003472095;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003472095;rank=34;version=1 18 havana CDS 120544 120757 . + 2 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 122042 122210 . + . Parent=transcript:ENST00000665241;Name=ENSE00003581729;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003581729;rank=35;version=1 18 havana CDS 122042 122210 . + 1 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 123337 124248 . + . Parent=transcript:ENST00000665241;Name=ENSE00002693450;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002693450;rank=36;version=2 18 havana CDS 123337 124248 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana CDS 125637 125738 . + 0 ID=CDS:ENSP00000499676;Parent=transcript:ENST00000665241;protein_id=ENSP00000499676 18 havana exon 125637 125866 . + . Parent=transcript:ENST00000665241;Name=ENSE00003880895;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003880895;rank=37;version=1 18 havana three_prime_UTR 125739 125866 . + . Parent=transcript:ENST00000665241 18 havana mRNA 20163 88917 . + . ID=transcript:ENST00000580206;Parent=gene:ENSG00000180777;Name=ANKRD30B-204;biotype=nonsense_mediated_decay;transcript_id=ENST00000580206;transcript_support_level=1;version=1 18 havana five_prime_UTR 20163 20247 . + . Parent=transcript:ENST00000580206 18 havana exon 20163 20468 . + . Parent=transcript:ENST00000580206;Name=ENSE00002721317;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00002721317;rank=1;version=1 18 havana CDS 20248 20468 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 24394 24508 . + . Parent=transcript:ENST00000580206;Name=ENSE00001626627;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001626627;rank=2;version=1 18 havana CDS 24394 24508 . + 1 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 24667 24840 . + . Parent=transcript:ENST00000580206;Name=ENSE00001676471;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001676471;rank=3;version=1 18 havana CDS 24667 24840 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 26727 26833 . + . Parent=transcript:ENST00000580206;Name=ENSE00001619132;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001619132;rank=4;version=1 18 havana CDS 26727 26833 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 29643 29780 . + . Parent=transcript:ENST00000580206;Name=ENSE00001745513;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001745513;rank=5;version=1 18 havana CDS 29643 29780 . + 1 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 32382 32446 . + . Parent=transcript:ENST00000580206;Name=ENSE00001775164;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001775164;rank=6;version=1 18 havana CDS 32382 32446 . + 1 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 35514 35918 . + . Parent=transcript:ENST00000580206;Name=ENSE00001621399;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001621399;rank=7;version=1 18 havana CDS 35514 35918 . + 2 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 41171 41201 . + . Parent=transcript:ENST00000580206;Name=ENSE00001784782;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001784782;rank=8;version=1 18 havana CDS 41171 41201 . + 2 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 43984 44056 . + . Parent=transcript:ENST00000580206;Name=ENSE00001686934;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001686934;rank=9;version=1 18 havana CDS 43984 44056 . + 1 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 49813 49903 . + . Parent=transcript:ENST00000580206;Name=ENSE00001743456;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001743456;rank=10;version=1 18 havana CDS 49813 49903 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 51788 51849 . + . Parent=transcript:ENST00000580206;Name=ENSE00001672877;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001672877;rank=11;version=1 18 havana CDS 51788 51849 . + 2 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 54355 54442 . + . Parent=transcript:ENST00000580206;Name=ENSE00001723800;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001723800;rank=12;version=1 18 havana CDS 54355 54442 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 56164 56192 . + . Parent=transcript:ENST00000580206;Name=ENSE00001669710;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001669710;rank=13;version=1 18 havana CDS 56164 56192 . + 2 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 56291 56363 . + . Parent=transcript:ENST00000580206;Name=ENSE00001606157;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001606157;rank=14;version=1 18 havana CDS 56291 56363 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 58867 58928 . + . Parent=transcript:ENST00000580206;Name=ENSE00001736208;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001736208;rank=15;version=1 18 havana CDS 58867 58928 . + 2 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 63229 63319 . + . Parent=transcript:ENST00000580206;Name=ENSE00001785342;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001785342;rank=16;version=1 18 havana CDS 63229 63319 . + 0 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana CDS 68171 68205 . + 2 ID=CDS:ENSP00000463332;Parent=transcript:ENST00000580206;protein_id=ENSP00000463332 18 havana exon 68171 68243 . + . Parent=transcript:ENST00000580206;Name=ENSE00003539503;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00003539503;rank=17;version=1 18 havana three_prime_UTR 68206 68243 . + . Parent=transcript:ENST00000580206 18 havana exon 69489 69517 . + . Parent=transcript:ENST00000580206;Name=ENSE00003643498;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003643498;rank=18;version=1 18 havana three_prime_UTR 69489 69517 . + . Parent=transcript:ENST00000580206 18 havana exon 69610 69682 . + . Parent=transcript:ENST00000580206;Name=ENSE00003622033;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003622033;rank=19;version=1 18 havana three_prime_UTR 69610 69682 . + . Parent=transcript:ENST00000580206 18 havana exon 70929 70957 . + . Parent=transcript:ENST00000580206;Name=ENSE00003669829;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003669829;rank=20;version=1 18 havana three_prime_UTR 70929 70957 . + . Parent=transcript:ENST00000580206 18 havana exon 71051 71123 . + . Parent=transcript:ENST00000580206;Name=ENSE00003460302;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003460302;rank=21;version=1 18 havana three_prime_UTR 71051 71123 . + . Parent=transcript:ENST00000580206 18 havana exon 74045 74106 . + . Parent=transcript:ENST00000580206;Name=ENSE00003550046;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003550046;rank=22;version=1 18 havana three_prime_UTR 74045 74106 . + . Parent=transcript:ENST00000580206 18 havana exon 75562 75652 . + . Parent=transcript:ENST00000580206;Name=ENSE00003510087;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003510087;rank=23;version=1 18 havana three_prime_UTR 75562 75652 . + . Parent=transcript:ENST00000580206 18 havana exon 80379 80407 . + . Parent=transcript:ENST00000580206;Name=ENSE00003561355;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003561355;rank=24;version=1 18 havana three_prime_UTR 80379 80407 . + . Parent=transcript:ENST00000580206 18 havana exon 80500 80572 . + . Parent=transcript:ENST00000580206;Name=ENSE00002695404;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002695404;rank=25;version=1 18 havana three_prime_UTR 80500 80572 . + . Parent=transcript:ENST00000580206 18 havana exon 81814 81842 . + . Parent=transcript:ENST00000580206;Name=ENSE00002732499;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002732499;rank=26;version=1 18 havana three_prime_UTR 81814 81842 . + . Parent=transcript:ENST00000580206 18 havana exon 81936 82008 . + . Parent=transcript:ENST00000580206;Name=ENSE00002707830;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002707830;rank=27;version=1 18 havana three_prime_UTR 81936 82008 . + . Parent=transcript:ENST00000580206 18 havana exon 84932 84993 . + . Parent=transcript:ENST00000580206;Name=ENSE00002700176;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002700176;rank=28;version=1 18 havana three_prime_UTR 84932 84993 . + . Parent=transcript:ENST00000580206 18 havana exon 86449 86539 . + . Parent=transcript:ENST00000580206;Name=ENSE00002684731;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002684731;rank=29;version=1 18 havana three_prime_UTR 86449 86539 . + . Parent=transcript:ENST00000580206 18 havana exon 88186 88917 . + . Parent=transcript:ENST00000580206;Name=ENSE00002716697;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002716697;rank=30;version=1 18 havana three_prime_UTR 88186 88917 . + . Parent=transcript:ENST00000580206 18 havana lnc_RNA 108977 124566 . + . ID=transcript:ENST00000320584;Parent=gene:ENSG00000180777;Name=ANKRD30B-201;biotype=retained_intron;transcript_id=ENST00000320584;transcript_support_level=2;version=8 18 havana exon 108977 109117 . + . Parent=transcript:ENST00000320584;Name=ENSE00002731419;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002731419;rank=1;version=1 18 havana exon 109443 109504 . + . Parent=transcript:ENST00000320584;Name=ENSE00003624717;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003624717;rank=2;version=1 18 havana exon 112416 112506 . + . Parent=transcript:ENST00000320584;Name=ENSE00003625674;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003625674;rank=3;version=1 18 havana exon 114725 114753 . + . Parent=transcript:ENST00000320584;Name=ENSE00003541229;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003541229;rank=4;version=1 18 havana exon 114852 114924 . + . Parent=transcript:ENST00000320584;Name=ENSE00003652561;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003652561;rank=5;version=1 18 havana exon 120544 120757 . + . Parent=transcript:ENST00000320584;Name=ENSE00003501392;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003501392;rank=6;version=1 18 havana exon 122042 122210 . + . Parent=transcript:ENST00000320584;Name=ENSE00003541760;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003541760;rank=7;version=1 18 havana exon 123337 124566 . + . Parent=transcript:ENST00000320584;Name=ENSE00001745545;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001745545;rank=8;version=1 18 . biological_region 19346 20318 486 . . external_name=oe %3D 0.61;logic_name=cpg 18 . biological_region 19611 19712 0.998 - . external_name=rank %3D 1;logic_name=firstef 18 . biological_region 19940 20468 0.998 + . external_name=rank %3D 1;logic_name=firstef 18 ensembl ncRNA_gene 31016 31122 . + . ID=gene:ENSG00000200645;Name=RNU6-1210P;biotype=snRNA;description=RNA%2C U6 small nuclear 1210%2C pseudogene [Source:HGNC Symbol%3BAcc:HGNC:48173];gene_id=ENSG00000200645;logic_name=ncrna_homo_sapiens;version=1 18 ensembl snRNA 31016 31122 . + . ID=transcript:ENST00000363775;Parent=gene:ENSG00000200645;Name=RNU6-1210P-201;biotype=snRNA;tag=basic;transcript_id=ENST00000363775;transcript_support_level=NA;version=1 18 ensembl exon 31016 31122 . + . Parent=transcript:ENST00000363775;Name=ENSE00001807050;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001807050;rank=1;version=1 18 havana ncRNA_gene 87979 97077 . - . ID=gene:ENSG00000265737;Name=AP006565.1;biotype=lncRNA;description=novel transcript%2C antisense to ANKRD30B;gene_id=ENSG00000265737;logic_name=havana_homo_sapiens;version=1 18 havana lnc_RNA 87979 97077 . - . ID=transcript:ENST00000581117;Parent=gene:ENSG00000265737;Name=AP006565.1-201;biotype=lncRNA;tag=basic;transcript_id=ENST00000581117;transcript_support_level=2;version=1 18 havana exon 87979 88465 . - . Parent=transcript:ENST00000581117;Name=ENSE00002723335;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002723335;rank=2;version=1 18 havana exon 96979 97077 . - . Parent=transcript:ENST00000581117;Name=ENSE00002694773;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002694773;rank=1;version=1 18 mirbase ncRNA_gene 101994 102070 . + . ID=gene:ENSG00000265499;Name=MIR3156-2;biotype=miRNA;description=microRNA 3156-2 [Source:HGNC Symbol%3BAcc:HGNC:38213];gene_id=ENSG00000265499;logic_name=ncrna_homo_sapiens;version=1 18 mirbase miRNA 101994 102070 . + . ID=transcript:ENST00000581101;Parent=gene:ENSG00000265499;Name=MIR3156-2-201;biotype=miRNA;tag=basic;transcript_id=ENST00000581101;transcript_support_level=NA;version=1 18 mirbase exon 101994 102070 . + . Parent=transcript:ENST00000581101;Name=ENSE00002716211;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002716211;rank=1;version=1 bcftools-1.21/test/csq/ENST00000580206/ascii-art.txt000066400000000000000000000015701467060157400212650ustar00rootroot00000000000000 CDS 35514 35918 . + 2 ID=CDS:ENSP00000351875 // skip 2 to start a new codon compound.ins-snv.vcf 35740 35750 1 01234567890------ F S W P A K ccc ccc ------ ccc ccc ATTTTCATGGC------CAGCAAAAGA ref CAAAAGA A F S W Q K K A K ccc ccc ccc ccc ccc ATTTTCATGGCAAAAGAAAGCAAAAGA alt P > QKK compound.del-snv.vcf 35740 35750 012345678901234567890 F S W P A K ccc ccc ccc ccc ATTTTCATGGCCAGCAAAAGA ref C--- T ATTTTCATGGC---CTAAAGA compound.del-ins.vcf 35740 35750 012345678901234567890 F S W P A K ccc ccc ccc ccc ATTTTCATGGCCAGCAAAAGA ref C--- ACCT ATTTTCATGGC---CACCTAAAGA bcftools-1.21/test/csq/ENST00000580206/compound.del-ins.vcf000066400000000000000000000005511467060157400225240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 18 35750 . CCAG C . PASS . 18 35755 . A ACCT . PASS . bcftools-1.21/test/csq/ENST00000580206/compound.del-snv.vcf000066400000000000000000000005761467060157400225500ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 18 35750 . CCAG C . PASS . 18 35755 . A T . PASS . 18 35756 . A C . PASS . bcftools-1.21/test/csq/ENST00000580206/compound.ins-snv.vcf000066400000000000000000000005511467060157400225660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 18 35750 . C CAAAAGA . PASS . 18 35751 . C A . PASS . bcftools-1.21/test/csq/ENST00000580206/short.gff000066400000000000000000000263001467060157400204710ustar00rootroot0000000000000018 ensembl_havana gene 100 125866 . + . ID=gene:ENSG00000180777;Name=ANKRD30B;biotype=protein_coding;description=ankyrin repeat domain 30B [Source:HGNC Symbol%3BAcc:HGNC:24165];gene_id=ENSG00000180777;logic_name=ensembl_havana_gene_homo_sapiens;version=14 18 ensembl mRNA 20068 124566 . + . ID=transcript:ENST00000358984;Parent=gene:ENSG00000180777;Name=ANKRD30B-202;biotype=protein_coding;tag=basic;transcript_id=ENST00000358984;transcript_support_level=1 (assigned to previous version 8);version=9 18 ensembl five_prime_UTR 20068 20247 . + . Parent=transcript:ENST00000358984 18 ensembl exon 20068 20468 . + . Parent=transcript:ENST00000358984;Name=ENSE00002240376;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00002240376;rank=1;version=1 18 ensembl CDS 20248 20468 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 24394 24508 . + . Parent=transcript:ENST00000358984;Name=ENSE00001626627;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001626627;rank=2;version=1 18 ensembl CDS 24394 24508 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 24667 24840 . + . Parent=transcript:ENST00000358984;Name=ENSE00001676471;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001676471;rank=3;version=1 18 ensembl CDS 24667 24840 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 26727 26833 . + . Parent=transcript:ENST00000358984;Name=ENSE00001619132;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001619132;rank=4;version=1 18 ensembl CDS 26727 26833 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 29643 29780 . + . Parent=transcript:ENST00000358984;Name=ENSE00001745513;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001745513;rank=5;version=1 18 ensembl CDS 29643 29780 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 32382 32446 . + . Parent=transcript:ENST00000358984;Name=ENSE00001775164;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001775164;rank=6;version=1 18 ensembl CDS 32382 32446 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 35514 35918 . + . Parent=transcript:ENST00000358984;Name=ENSE00001621399;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001621399;rank=7;version=1 18 ensembl CDS 35514 35918 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 41171 41201 . + . Parent=transcript:ENST00000358984;Name=ENSE00001784782;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001784782;rank=8;version=1 18 ensembl CDS 41171 41201 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 43984 44056 . + . Parent=transcript:ENST00000358984;Name=ENSE00001686934;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001686934;rank=9;version=1 18 ensembl CDS 43984 44056 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 49813 49903 . + . Parent=transcript:ENST00000358984;Name=ENSE00001743456;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001743456;rank=10;version=1 18 ensembl CDS 49813 49903 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 51788 51849 . + . Parent=transcript:ENST00000358984;Name=ENSE00001672877;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001672877;rank=11;version=1 18 ensembl CDS 51788 51849 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 54355 54442 . + . Parent=transcript:ENST00000358984;Name=ENSE00001723800;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001723800;rank=12;version=1 18 ensembl CDS 54355 54442 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 56164 56192 . + . Parent=transcript:ENST00000358984;Name=ENSE00001669710;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001669710;rank=13;version=1 18 ensembl CDS 56164 56192 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 56291 56363 . + . Parent=transcript:ENST00000358984;Name=ENSE00001606157;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001606157;rank=14;version=1 18 ensembl CDS 56291 56363 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 58867 58928 . + . Parent=transcript:ENST00000358984;Name=ENSE00001736208;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001736208;rank=15;version=1 18 ensembl CDS 58867 58928 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 63229 63319 . + . Parent=transcript:ENST00000358984;Name=ENSE00001785342;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001785342;rank=16;version=1 18 ensembl CDS 63229 63319 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 68049 68077 . + . Parent=transcript:ENST00000358984;Name=ENSE00001629126;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001629126;rank=17;version=1 18 ensembl CDS 68049 68077 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 68171 68243 . + . Parent=transcript:ENST00000358984;Name=ENSE00003619909;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003619909;rank=18;version=1 18 ensembl CDS 68171 68243 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 69489 69517 . + . Parent=transcript:ENST00000358984;Name=ENSE00003534627;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003534627;rank=19;version=1 18 ensembl CDS 69489 69517 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 69610 69682 . + . Parent=transcript:ENST00000358984;Name=ENSE00003491240;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003491240;rank=20;version=1 18 ensembl CDS 69610 69682 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 70929 70957 . + . Parent=transcript:ENST00000358984;Name=ENSE00003507996;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003507996;rank=21;version=1 18 ensembl CDS 70929 70957 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 71051 71123 . + . Parent=transcript:ENST00000358984;Name=ENSE00003477650;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003477650;rank=22;version=1 18 ensembl CDS 71051 71123 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 74045 74106 . + . Parent=transcript:ENST00000358984;Name=ENSE00003464535;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003464535;rank=23;version=1 18 ensembl CDS 74045 74106 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 75562 75652 . + . Parent=transcript:ENST00000358984;Name=ENSE00003568491;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003568491;rank=24;version=1 18 ensembl CDS 75562 75652 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 80379 80407 . + . Parent=transcript:ENST00000358984;Name=ENSE00003518163;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003518163;rank=25;version=1 18 ensembl CDS 80379 80407 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 94433 94505 . + . Parent=transcript:ENST00000358984;Name=ENSE00001784236;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001784236;rank=26;version=1 18 ensembl CDS 94433 94505 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 100106 100136 . + . Parent=transcript:ENST00000358984;Name=ENSE00001749792;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001749792;rank=27;version=1 18 ensembl CDS 100106 100136 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 103211 103283 . + . Parent=transcript:ENST00000358984;Name=ENSE00001742133;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001742133;rank=28;version=1 18 ensembl CDS 103211 103283 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 109039 109117 . + . Parent=transcript:ENST00000358984;Name=ENSE00001631899;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001631899;rank=29;version=1 18 ensembl CDS 109039 109117 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 109443 109504 . + . Parent=transcript:ENST00000358984;Name=ENSE00003587900;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003587900;rank=30;version=1 18 ensembl CDS 109443 109504 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 112416 112506 . + . Parent=transcript:ENST00000358984;Name=ENSE00003649247;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003649247;rank=31;version=1 18 ensembl CDS 112416 112506 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 114725 114753 . + . Parent=transcript:ENST00000358984;Name=ENSE00003490819;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003490819;rank=32;version=1 18 ensembl CDS 114725 114753 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 114852 114924 . + . Parent=transcript:ENST00000358984;Name=ENSE00003634416;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003634416;rank=33;version=1 18 ensembl CDS 114852 114924 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 120544 120757 . + . Parent=transcript:ENST00000358984;Name=ENSE00003472095;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003472095;rank=34;version=1 18 ensembl CDS 120544 120757 . + 2 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 122042 122210 . + . Parent=transcript:ENST00000358984;Name=ENSE00003581729;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003581729;rank=35;version=1 18 ensembl CDS 122042 122210 . + 1 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl CDS 123337 124308 . + 0 ID=CDS:ENSP00000351875;Parent=transcript:ENST00000358984;protein_id=ENSP00000351875 18 ensembl exon 123337 124566 . + . Parent=transcript:ENST00000358984;Name=ENSE00003887179;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003887179;rank=36;version=1 18 ensembl three_prime_UTR 124309 124566 . + . Parent=transcript:ENST00000358984 bcftools-1.21/test/csq/ENST00000580206/single.del-ins.vcf000066400000000000000000000005251467060157400221620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 18 35750 . CCAGCA CCACCT . PASS . bcftools-1.21/test/csq/ENST00000580206/single.del-snv.vcf000066400000000000000000000005521467060157400221770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 18 35750 . CCAGCA CCT . PASS . 18 35756 . A C . PASS . bcftools-1.21/test/csq/ENST00000580206/single.ins-snv.vcf000066400000000000000000000005231467060157400222220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 18 35750 . CC CAAAAGAA . PASS . bcftools-1.21/test/csq/ENST00000580206/test.cmd000066400000000000000000000027431467060157400203170ustar00rootroot00000000000000{bin}/bcftools csq -f ENST00000580206.fa -g ENST00000580206.gff compound.ins-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g short.gff compound.ins-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g ENST00000580206.gff single.ins-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g short.gff single.ins-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g ENST00000580206.gff compound.del-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g short.gff compound.del-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g short.gff single.del-snv.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g ENST00000580206.gff compound.del-ins.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g short.gff compound.del-ins.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' echo {bin}/bcftools csq -f ENST00000580206.fa -g short.gff single.del-ins.vcf | ../sort-csq | {bin}/bcftools query -f'%POS\t%REF\t%ALT\t%BCSQ\n' bcftools-1.21/test/csq/ENST00000580206/test.cmd.out000066400000000000000000000044701467060157400211240ustar00rootroot0000000000000035750 C CAAAAGA inframe_insertion&NMD_transcript|ANKRD30B|ENST00000580206|NMD|+|353P>353QKK|35750C>CAAAAGA+35751C>A,inframe_insertion|ANKRD30B|ENST00000358984|protein_coding|+|353P>353QKK|35750C>CAAAAGA+35751C>A,inframe_insertion|ANKRD30B|ENST00000665241|protein_coding|+|353P>353QKK|35750C>CAAAAGA+35751C>A 35751 C A @35750 35750 C CAAAAGA inframe_insertion|ANKRD30B|ENST00000358984|protein_coding|+|353P>353QKK|35750C>CAAAAGA+35751C>A 35751 C A @35750 35750 CC CAAAAGAA inframe_insertion&NMD_transcript|ANKRD30B|ENST00000580206|NMD|+|353P>353QKK|35750CC>CAAAAGAA,inframe_insertion|ANKRD30B|ENST00000358984|protein_coding|+|353P>353QKK|35750CC>CAAAAGAA,inframe_insertion|ANKRD30B|ENST00000665241|protein_coding|+|353P>353QKK|35750CC>CAAAAGAA 35750 CC CAAAAGAA inframe_insertion|ANKRD30B|ENST00000358984|protein_coding|+|353P>353QKK|35750CC>CAAAAGAA 35750 CCAG C inframe_deletion&NMD_transcript|ANKRD30B|ENST00000580206|NMD|+|353PA>353P|35750CCAG>C+35755A>T,inframe_deletion|ANKRD30B|ENST00000358984|protein_coding|+|353PA>353P|35750CCAG>C+35755A>T,inframe_deletion|ANKRD30B|ENST00000665241|protein_coding|+|353PA>353P|35750CCAG>C+35755A>T 35755 A T @35750 35756 A C missense&NMD_transcript|ANKRD30B|ENST00000580206|NMD|+|355K>354Q|35756A>C,missense|ANKRD30B|ENST00000358984|protein_coding|+|355K>354Q|35756A>C,missense|ANKRD30B|ENST00000665241|protein_coding|+|355K>354Q|35756A>C 35750 CCAG C inframe_deletion|ANKRD30B|ENST00000358984|protein_coding|+|353PA>353P|35750CCAG>C+35755A>T 35755 A T @35750 35756 A C missense|ANKRD30B|ENST00000358984|protein_coding|+|355K>354Q|35756A>C 35750 CCAGCA CCT inframe_deletion|ANKRD30B|ENST00000358984|protein_coding|+|353PA>353P|35750CCAGCA>CCT 35756 A C missense|ANKRD30B|ENST00000358984|protein_coding|+|355K>354Q|35756A>C 35750 CCAG C missense&inframe_altering&NMD_transcript|ANKRD30B|ENST00000580206|NMD|+|353PA>353PP|35750CCAG>C+35755A>ACCT,missense&inframe_altering|ANKRD30B|ENST00000358984|protein_coding|+|353PA>353PP|35750CCAG>C+35755A>ACCT,missense&inframe_altering|ANKRD30B|ENST00000665241|protein_coding|+|353PA>353PP|35750CCAG>C+35755A>ACCT 35755 A ACCT @35750 35750 CCAG C missense&inframe_altering|ANKRD30B|ENST00000358984|protein_coding|+|353PA>353PP|35750CCAG>C+35755A>ACCT 35755 A ACCT @35750 35750 CCAGCA CCACCT missense|ANKRD30B|ENST00000358984|protein_coding|+|354A>354P|35750CCAGCA>CCACCT bcftools-1.21/test/csq/ENST00000593942/000077500000000000000000000000001467060157400166605ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000593942/ENST00000593942.fa000066400000000000000000000507661467060157400210370ustar00rootroot00000000000000>19 19:7541741-7562355 CCTTCACCCCTGAGCCAGGCGCCAGCACCACAATGTTTAATTGATTCCCGTTCCAGCTTT CTCAAGGCACGACAGGCCCCCTCTTCCTCATCTTGATTTGGATACAAGACGCCAGCTGGC AGGCAGGAGGTGCTGCTGAAGCCCTGCACGGCCCCTGAAAACTGTCACGGCTCAGGAGCT CCAGGCTGAGGCCTGGGGGACCTCGCATCAGTCCCTCCACCCACCCTGCCCATGGGTTTC ACCACAGGCAGCTCCATGAGAGCCCCGGCCCCTGCCCTGGCGGCTTCTGCTTTGCGGGAA GGGCCCTCCGTGGGCTCTGGCTGTGTCCCTGTGCTCTTCCGGCAGTGTCAGGGGGTAGTG GCCTCGGCCTGGCCGCCGGCCCGGGCCGCCTGGTACATGCTGAGGATTGAGGAGATGGTG CCCATGAGGCCCACTAGCCACGGCGGGAAGCGGCCGGCCCACAGCACGCCCCGGGGCAGC CAGTGCACGGCGTTGGCCAGGTCGGCCAGGTTGCTGAGAAGTGACAGCGCCTCCGACTGC ATCTGCGCCTCCATGGCCCTCCGCTTGCCCCGGGGCAGCGGGCTGTGGGGCAGAGAGGGG CCGCTTACACTCACGCTCACACCTGCCTGCCCTTCCCAAGCCCCTGAATGCCCTGTGTGG CCTGGCAGCCCTGAGCCCCTGCCTGTGAGTGGGAGGAGCTGGCAGGACTGAGGTGGCCTC CCTGACCATCCACAGAGACTGAGTCCCCATCACCCCCCCGACCCAAGCACGAACAGGGCA GGAACCCGGGTCCAAGTCCTCAAATCCACACCTCACTCCTCGTCCTGAACACCCAGAGAT GGGGATTCCTTGTGAAAAACAGAAAGCACAAATGCACTTTGGGAGGTGTGGAGGGAAGGG GGAACCCCCAGGAGCGTGGCCTGTGCCTGCCCGGCCTTTCTTTATCAGGATGACACAGTG ACGATAAGCCTGGCCAATATGGCGAGACCCCATCTCCACCAAAAAATAAAAAACAAAATT AGCCAGGCGTGCTGGCCCGTGCCTGTAGTCCCAGCTACTCGGGAAGCTGAAACAGGAGGA TCAGTTGAGCCCAGGAGGCAGAGGCTGCAGTGAGCCAAGATGGCACCACTGTGCTCCAGC CTGGGCAACAGAGCAAGACCCTGTCTCAAAAAACAAAAAGAAAAAGCAACAGTAACAATG GCCATGGCCTTCGGGAAATTGATCATTCTCTCCTGCTGGGGGCGCAGCCATGAAGGCTCA GCCCTGGAGTCCCCGCTCAAGCAAGCCTCAGTTTCTCCATCTGTAAAAGGTACCGCCACC CACCAGAGGCTGTGATGACTCCCCCATGACCTGAGCACAACAGTCCCCAGCATGGGCCTG CACAGGGGTGGCTGCGAGCCGGGATCCCACGCCTGCTGGAGGGAGTGGGCCTCCCTGCTG GGTGATCACGGGCTCCTACCTGGTGAAGGGCGCCGTGGGGCTCCGCAGCCTCTGTCTCAG TTTCAGCAGCATCCACAGGGACCTGCAGCACCAGAGCCCGAGGGAGGATGCCCCGGCGGG GAGCAGGAGGGTTAGCTCCACAACGCTGGCCCCGGACATACAGTCTGGGACAGGTGCTGC ATCTCGGATAAACGGCCTGCCCTCTCCCTGCCCCCACAGTCCCACACCCTCCTGGCTGTG CCTCATGCTCCCGGGGACTCATCTCTAACACGGCCCCGTCCCACCCGGGACATCGTCCTG CACTTCTGACGTGGCCATCCAGGGCCTGGCCCAGCCTCTGCAAACCACTGGCAAGTGCTC AAAGGAACATCAAGCCCCGTGAGGTGTTCACAGCCTGGCAGGGAGTCCTACACAGAAAAG GATGCCAAGAGGCCCGCAGTTGGACAGGCGTGGGGACGCCGTTTCCCCTCCGGGCCTCAG CTGCCTTGTCTGCTCTGTGTGGAAAGGTCCAAATCAGTGCCATGCCAGCACCCCCTGCAC ACACACCCCGGACATTGGCTGGACCTGTCTGGATGATCCCCTGGGCCCCCAGGGCTGGCA TCTGCAGGCTGAGGAAGGGGCTACCCAGTGGGCAGCCTCTGTGCTCCCAGCAGGCTCTGC AGCCGTGCATGGCACCCACCCGGGCCAGTCCACCAGGCACCTGCACTCTCCAGCCTCGGC CGTGGGGTGTGCCGGGTTGTGACTGTGACAGAATGGGCAGGGCCTGGTCACAACTCCTCT GGCCACTGGGTACCCAGGGTGCAGGATGCAGGATAGCGCCAGTGGCACAGCAGGTGGGAG CCTCCTGGGGGGCTAGGGAAAAACACTGATTCCTGGGCTCCCCAGACCCACAGAATCAGA AGCTCTGGGCCAAGCGCGATGGCTCACACCTGTAATCCCGGGACTTTGGGAGGCCAAGGC CGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATGGTGAACCCCTGT CTCTACTAAAAATACAAAAATTAGCTGGGGGTGGTGGTGGGCGCCTGTAATCCCAGGTAC TCGGGAGGCTGAGGCAGGAGAATCACTTGACCCCGGGAGGTGGAGGTTGCAGTAAGCCAA GATCGCACCACTGCACTCCAGCCTGGGCGACAGAGGAAGACTGTGTCTCAAGAAAAGAAT CAGAAGCCCTGGGCGCCGGACCCAGGCATCTCCATTTAGCAACCTCCTGGCTGATGCTCC GGCAGCCCTGGGCCTTAGGGCAGATGTCTGGTCATGATGAGCACACATGGAATGCTCTCC ACCCACTCCCCCTGCTCACTGCAAATCCAGAGAAATGATGAAAAACCACATGCCCGAAAC AAGAATGCCGCAGCAGGCGGGGCACACAGGACTTCGATGGCCGTGAAACAATTCCATTTG ATTCTGCAAGGGGGGACACGTGTCAGTGTCCAAACCCATAGGATGCCCAAAACCTAGCGT GAACCCTAACGTGAGCTACTCACTTGGGGTGATGATGGATCCATGGAGGGGCATCAGTTG TAACAAATGCACCATGTGGATGCTGCCAGTAGTCGGGGAGGCTGTGTGTGGGGGTATATG GGAGCTCTCTGAACGTTATGCTCAATTTTGCCATGAGCCTAAAACTGCTCTAAAAAAATA AAGTCTGGGCCGGGAGTGGTGGCTCACGCCTATAATTCCAGCACTTAGGGAGGCCAAGGC AAGTGGATCACCTGAGCCCAGGAGTTGGAGACCAGTCTGGGCAACATGGCAAAACCGTGT CTCTACAGAAAAAAAATTACAAAAATTAGCCAGATATGGTGGCACAGCCTGTGGTCCCAG CCACTCAGAAGGCTGAGGTGGGAGTATTGTTTGAGCCCAAGGGGCGGAGGTTGCAGTGGG TCAAGATTGAGCCACTGCTTTTCAGCCTGTCTCAAAAAAAAAAAAAAAGTTTATTTAAGC AAAAAAGAAAGGAACCAAGGCTGCCCCTAAAATACAAACCAGAGGTCACGAGGCACCCAG AGGAAGGTGGCGGAAGAGAGGCTGTGAGCCAAGGCCCCCCTCTGACCGGAGCCCCAGGAA CATCCAGGCTGGGCCCAGGCACCCTCCCCCAGGTCTCCCAGCACACAGGGAAGGCCAGCA GCACAGACACCGCTGCCTCCAGGGGCCATGGCCATGAAACATGACCCTTTTGAGACAGCC AAAATGCACAGGCAGGGTATTAGGTCAAAGGCTGGAAAAGAACCACCCAAGCTTGAACAG TGGGAGTCTGGGTTGGATTGTGGGTAATTCGAATCTTCTACTCTGAGGTTTATCTATTTT CCAGATTGTCTACGGTAAGCATGTAATTAGGACATCTGTGCCGGGGGGAAAACAAGAACT ACTGAGAGTCAGAGCCTCGACCAGGGACAAGCAAAGCTTCCCCCAGAAAAAGGACACAGC CTGCCTGAGGCTGGGGGCAGCCGCACCTCACCCCAGCGATCTAAGAGCCCTTCACAGCCA CTGAAACATGGAGACCAGGGGGCCCAGCTCCTGCTGGTGTTTTCAGGGGCAGGGGATTCT GACTCAGCGCATTTGCAAAGAGGAAAATGTTTGGGAGGAAACCATTACTAGAAAGTTCTA GAAACTATATGGTTTTTTGGAGGCACAGAACTAGTCAGGAAACTGCTGACTGTTTTCTCT GGGGTGTCGGCTGACAGCAACGCCAGCAAGACTCAGGGACCCGGGTAAAGGCCACTCCGC TGGCTGCTTCTCACAGGCCCTGGAGTTACTTCTTCTTTCTAAGTGTGGTCAGCAGAGTCA TGACCCCTTCTAAAATGTCCATGTCCTGAACCTGTCAACATGTTCACCTCCAAGGCAAAG GATATTTTGCCGATGGGATTAAGCTAAGGATTTTTTCTTTTTTTGACACGGAATCTTGCT CTGTCGCCAGGCTGGAGTGCAGGGGTGTGATCTCGGCTCACTGCAACCTCCACCTCCCCA AATTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAAGTGTGCACCAC CAAGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGC TGGTCTAGAACTCCTGGGCTCAAGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGAT TACAGGCATGAGCCACCACGCCCAACCTAAGCTAAGGATCTTGAGATGGGGTATTACCCT GGATCATCCAGGTGGTCCCCATGTCATCATAGGGGTCCTTATAGGAGGGAGGAAGGAGGA TGAGGGTCAGGGAAGGAGGTGTGACGCTGAAAGCAGAGGTCATGCTTGGAAGATGAAGGA AGGGGCCATGAGCCAAGGAATGTGGGTGGCCTCCAGAAGCTGGAAAATCCAAGGAAACGG ACCTCCCCCTGGGACCTCCAGAAGGCATCAGCGCCTGCTGACACTAGCCCAGGGAGTGTT CTGACTTCCAGCCTTCAGAATCCTAAGATAAGAAGTTTCTGTTGCCCAGCACTACAGAGT TGTGCTAATTTGTTCCGACAGTTATTCTAAACAAATACACCCACAAAAGGAAGAAACAAC AAAACCTCCAAGGAAAACTCTAAGAGGCAAAGACCCACCGCAGTCTGAAGCCTGTGCTGT TGCTGGGGCCGCTGCCACTTTGCTAAGGAGGCACCGCCCAGGGACCTTGGGTGCTCCCTT CTGGCCCATGCCACTTACCTGGCAACCCCCAGGAGCAGAGAGAGGGCCCACAGGGTTGTA CTCAGCGTCCACCACCGAGAAGAGTCCACGTGGAGGACCCGGGCATCAGCCGCCCAGGCC ACGTGCTCACAGGGGTAGTAGAGCTGGTCAGCCAGGTTCCCTAGGACGGAGACACAGCGG ACAAAGGCGTCCTCCTCCTGCAGGACCAGGAGCAGAGGGGGCCTAGGGTCAGACTTACCC ACTGCCCATTTTAGCACCGTAGCCATGCCAGGTGGCAGAGAGCTATTTCCTGACCCCAGT CCCTGGGCCGTGTCCAGGCCTGGCAGGCCCCGCGGGAGAAAGGCTCTGGGGCTGGGGTCC CCGCACAGGCCTGATTTCTGTGTCTCGGCAGCACGGTGCTCAGTGCCCCTTGGAGGGAGG CTCTCAACGCAGCTGTGCAGTGCAGTCCTCTGCAGAGCTTCAAAAACCCCATGCCCAATG CCAGCCGTGAGGATTCTGCCTCACTCAGCCTGGGGCAGGCCCCAGTACCGGGAATTTTCA CAGGGAATTTTCACATTCCCAGGGGATTCCCAGGCCAAGTTGGGAGCCCTGTGTCAGAGC CTTCCTTCCCAAAGGCTTCCAGTTCCTGCACAGGTGGGGACCTCTGTTGCCAGACTCTAT GCAGGGAGCATGAGGTGGCCCGCAGCGAACCCTGACCAGGCTGAGATGGTGTGCCAACCC TTGGGCCACCGCACGCCCACTGCTGACCACGCGCCAGGCACAGTGCGGCAAGGCTCATGG CCTCCCTCAACTCCGAGCAAGTTACAGACGGCCACGCTGAGGCTCTCAGGGAAAGCCGCT GGCCCCCAGTTCCGGCAGGGATGGGCCTCCAGGCCCTCGAATTGCAATGCACACGCGGGC TCTCGGTCCTGCACAGTGCCCATACCCTCTGCCCCAAGTTCTTAATCACACGGCCTAGAG CCAGCGAGGCAGGACCAGTTGAGGCTGTAGAAACCAGCGCTGAAGCCTGGTTTCTGGGAC TGGAGCCCCGCAGCCAACCGGGGGACCCGCCCCCTTGGGACCCCACCCCCCTTGGGACCC CGCCCACCGTGACCCCGCCCCATCGGAGCCCCGCCCCCTCTACCTTTATCCTCCTTGTTA CCTGCCACACCCTTCCCCTCCTCTCTGACTTCCCAGGAAGCTCCTCCCCGCCCCCACCGC TGATTCCAGATGCTGCTCTCCTTCTTTCTGGCCAGTCATGATCCTACCTCCCTCCGGGCT CTGAACCTCACTCCAGCTTCCCTCATCTGCCTGGCGCGTCCTGGCACATTGCCCACCTCC CTGAGGATGGCGGACCCCGCCCCAATGTGCTCATTCCGCCCGGATTTCCTGAGAAGCGGC AGGGTCCAGGCTAGACTCTGGGGAGGGGCAGAGGCTCACCAGGGCAGGGAGGAACGCAGA CATATAAACCGGGAACCCAACAAACAGGGCTCTTGTTCTGGCCAAGGGACACTCGAGGTG CAAGGGCCTCCACCCCTTGCCTGAGGGCTCTTCCACAGAGGGCATAGAGGAACGAGGGGT CTCAGGGATGCACCAGAGCGCTGTCCTAATCAGACACGGAGGAGGAGGATGCTATAGGTG TCAAAACAGGAAGGCGGCCCACAGCAACACTTATGATATAGGATGATCAGGCCAAGGACA CGTGGTGCTGAACACGGTGGGGTTGGGATTTCGGGGCGGGGAGCACCTGAGTAGCAAGTG GCTCAGAGAGGTGATCCCTGGGAGGACAGAGAGAACAGACAGGGCAGCCCAGGGAGGGGC AGGACGCTGAGAGGCTGGCCCACGCAGCCTCTGAGATCATCCCGTGGGGGGCAAGATGGC TCTCTAGATAGGCTGGCACGCCTGTGGGACGCCGCAGGGACAAGGCTACTCTCTGCAGCA CTGTCGCAATAGCAAAACCTTAGAAATCATTGCCCTGTGCGTCAACCAGAGGCCAATTAA ATAAATCCGAAGCTGCATAGCAGAGCACTATGTGGTCCTGAGAACGCAGCTCTTTCTAGA CCGATAAGAAATGATCTGTGGCCAGGCGCGGTGGCTCACGCCTGTCATCCTAGCACTTTG GGAGGCGGGGCAGGTGGATCACTTGAGCCCAGGAGTTCAAGGCCAGCCTGGGTAACATGG CAAAACCCTGTCTCTACAAAAGATACAAAAAATTAACCAGGTGTGGTGGTGCACCTGCAG TCCCAGCTATTCCGGAGGCTGAGGTAGGAGGATCACCTGAGCCCGGGAAGTCAAGGCTGC AGCGAGCCATGATCACGCCACTGTACTCCAGGCTGAGTGACAGAGTGAGACCCTGTCTCC AAAAAAAAAGAAAGATAAAGAAATGATGCCGAAGCTGTACCGTTAAGTGAAAAAAGCACT GTTTATGTAAACCATATGTATTTGCCTATGCGAGTACAGGAAATCTCACAAAGGAGACAC AAGAAGCTGACCACAGGGCCGGGCACGGTGGCGCACACCTGTAATCCCAGCAGTTTGGGA GGCTGAGGCAGGTGGATCACTTGAGGTCAAGAGTTCGAGACTAGCCTGGCCAACATGACA AAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGGGGGTGCCTGTAAT CCCAGCTACGTGAGGGGCTGAGGCAGAAAAATCATTTGAATCCCGGAGGCAGAGGTTGCA GTGAGCCGAGATCACGCCACTGCACTCCATCCTGAGTGACAGAGTGAGACCTTGTCTCAA AAAAAAAAAAAGAAGCTGACCACAGTGGCTGCCTCTGTGGGGAAAAATTGGAGGCCTGGA AGATCAGGAAGGAGGGAGGTTTTTTAAAATTATATCCTCCTTTGGAATGTGTGAACGTTT GCTATTTTTAAAAATTTAAATCAAAATGAGAACATCTGATCCTCTCAAAGAAGAAAGTGA AATTTTTAAAAGTAATAAACTACCCACGCAGGGAGCACTTTGGGACAAGACTATAAAACG CCCATGGTGGCTCACGCCTGCCATCCCAGCACTCAGGGAGGCTAAGGCGGGAGGACCACC TGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGGTCACTCCACTGCACTCCAGCCTGTA TGACAAAGCAAGACCCTGTCTATAAAAAAAATTTTTTTTGTTTGTTTTATTTGAGATGGA GTCTCGCTCCATTGCCCAGGCTGCCAGTGCAGTGGCACAATTCTCGGCTCATGGCAACCT CCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGAACTACAGG CACACGCCACCATGCCAGGCTAATTTTTGTATTATCAGTAGAGACAGGGTTTTTTTTTTT AGACGGAGTCTCGCTCTGTCGTCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGC AAGCTCCACCTCCCGGGTTCAGGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACT GCAGGCGCCTGCAACCACACCTGGCTAATTTTTTGCATTTTTAGTAGAGACGGGGTTTCA CTGTGTTAGCCAGGACGGTCTCCATCTCCTGACCTCGTGATCCGCTCGCCTCAGCCTCCC AAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCAGCCGAGACAGGGTTTTACCATGT TGGCCTGGCTGGTCTCGAACTCCTGACCTCATGATCCGCCAGCCTTGGCCTCACAAAGTG CTGGGATTACAAGCATGAGCCACTGTGAGGGGCCAAAAAATTTTTTAAAAAATGTCCACT CAGGTCCGCACCCTACTCCCTAGAGCCCCACAAACCCTGTTACCTGTGCCCCCAGGCCAT ATTGCTTAGTGTAGACAAACATGGCCAGGTCATCAAAGAGTCGCAAGATGGTCCTGCAGT GGCTGAGTTGGGTGGACACCACCAACAGACGTGTCCCCACTTCGGACCTGGCGGGACACT GTTCAACCAGAACTCCACCAACCAGCTGGCAGCAGTACCCCAGCACTCGGATCTGTGGGA AACCAGAAGCAGTCAGTGTGGCCCTCCTGTTCTGCAGAACTGAGCTGCATCCCCCCATAC CTGGCCCCGGGCCCCGCTGGATTGAGAGTGTGGAAGATTCTCTTTTTTTTTTGAAAGAGT CTCACTCTGTCATCCAGACTGGAGTGCAGTGGCACGATCTCGGCTCACCGCAGCCTCCAT CTCCCATGTTCAAGCAATTCTTGTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGCGCC CACCACCACACCCTGCTAATTTTTATATTTTTTGTAGAGACAGGGTTTCACCAGGTTGGC TAGGCTGGTCTCAAACTCATAACCTCAGTGATCCACCTGCCTTAGCCTCCCAAAGTGCTG GGATTACAGGCATGAGCCACCGTGCCTGACCCAAGAGTTTGGAAGATTCTAAATCTACAA AGTGACAGTAAAAGCTGAAAGTTTAGGTGGGGCACAGTGGCTCACACCTGTAACCCCAGC ACTTTGAGAAACCGAGGTGAGAGGATGCCTTCACACCAGGAGTTTGAGACCAGCCTGGGC AACATAGCAAGACCCTGTGTCTACCAAAAAAATTTTTTTTTTTGAGACGGAGTCTTGCTC CGTCACCTAGGCTGGAGTGCGGTGGCGCGATCTCGGCTCACTGCAAGCTCCACCTCCCGG GTTCATGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACC AAGCCCACCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATTTTAGCCAGGAT GGTCTTGATCTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTAC AGGCGTAAGCCACCGCGCCTGGCTACCAAAAATTTTTTTAAGTTAACAGGGCATGGTGGT TACTTGGGAGGCTGATGCTGGAGGATCACTTGAGCCCAGGAGTTCCAGACTGTAGTGAGC TGTAATCGTGCTACTACACTCCAGCCTGGGCAACAGGGCGAGACCCTGTCTAAAAAAAGA AAAAGAAAAAGAAAAAAAAAGCTGGAAGTTTAAAAACATACTTGGAGGTGGGACAAATGA AGAAACATGACATCATTGATGTAACTGAAGGGCACAGCCTTTGGGAACAGATGTGACAGG AACAAAGAAAACAAAGCTCCTTACTTCCCACCTCCTAGGTCCTTCTTTTCCCAGGTGGCA GGAAGCCACAGCTAAAGTGTATATTTACATCTACCTGCCTGGACCAAAGCCTTTGGATGT GCTGAATGGTGGGCACAGGTGATCAGGCCTCAACCCAGTGAACAACAGGATAATTTGGTA GAATTACTTTAGAGAGAAAGAACCTACTCAGTAGGTGATGTGGAGCCTTCTGAAATAGGT CATCTTCACTACTCAGATCTTTTTTCTTTTGGAGACAGAGTCTTGCTCTGCTCCCCAGGC TCGAGTGCAAAGGTGTGAGCTCACTGCAACCTCTGCATCCCAGGTTCAAGCAATTCTCCC GCCTCAGCCTTCCAAGTAGCTGGGACTACAGGCACGCACCACCACATCCGGCTAATTTTT GTATTTTAGTAGAGACGAGGTTTCATCACTTTTCCCAGGCTGGTCTCAAACTCCTGAGCT CAGACAATCCACCCAGCTCAGCCTCCCAAAGTGCTAGGATCACAGGCGCGAGCCACCACG CCTGGCCTCCCTTATATCTTTATTTTACCTGCTTTTCAGAAATTGCTTGTTCCTGTTGTT TTATTTATTTTTACTTGTAATTCCTTTCCAGCCCCATTATAATGGCAAAACACTGCAATC TGAATGTTCAACTCGGGGGAGATTTGTTAACCCACCCCCCCAATCATAAGATATTTGAAT GGAATCTAAATGCCTAGCCACCAGTACACCGCCTGGTACAACCTGAATGTCTACCTATAA GAGACTGGTGGGGACAAGCTAAGAGTCCAGACTCAGGGGCATGGATGGCATAACCTAAAT GTTCAACCATATGGGACTTGATTGGAACTAAAAACTGTCCAGCCATAGGGAGAGTCTTGC AATATCCTAAATCCCCACATGAGATTGTTTGGGACAACCCAGGGACCAACTACAGTGGCC CGGTCAGATCCTAAATGTCCAAACATGGGAATCTGTTTGGTATGTAAACGTCCAGCCAGG CTGGGTTGGCAGAGACGATCTAAATGACCAACTGGGGTTTTGTTGGAACCCATCGCTGCT TAGGCATGGCAGGGCCCAGGCCATGGCGTGTTCTTTGGTCTAGGTTGGCTGAAACAACCT AAATGCCCAACTATAGGGAATCTGGTTGGAAGTGAATGTCCAGCCACAGGGGAGCCCTGC AACATCCCAAATCCCAACACGAGATTGTTCAGGACAACTTCAGTGGCCTGGTCGGATCCA AAACGTCCAAACACGGGAATCTGGCCAGTGTGTCAATGTCCAGACAGGTTGGGTTGGCAG AAACTATCTAAATGTCCAACGCTGGCCAGACGCGGTGGCTCACGCCTGTAATCCCAGCAC TTTGGGAGGCCGAGGCAGGTGGATCGCTTGAGGCCAGGAGATCGAGACCATCCTGGCTAA CACGATGAAACTCCGTCTCTACTAAAAATACAAAAAAATAGCAGGGAGTGGTGGCGGGCG CCTGTAGTCCCAGCTACTCGGGAGTGCTGAGGCAGGAGAATCGCTTGAACCCGGGAAGCG GAGGCTGCAGTGAGCAGAGATCGCACCACTGCACTCCAGCCAAAATAAATAAATACATAA ATGTCCAATGCTAGGGCACCGCATTTGAGCCTAGCTCGGACGGGGCCTCTGCGACGGAGT ATCCTGGGCGACCCCGTCCCCTCTCTGGCCCGTTTCCCAGTCTCTGAGCTTGGGCCAAAC TCTAGGACCTCCGGCCCCGGTCCGCCCCTGCCTCACCAGGCGGTCCCGGCCCCTGTACGA CTCCAGCGCCGACGCCAGGCCGCTCAGCGACGCCATGGCAACTCCGTGACGTCACCGCGA CGTCGGCGCGCCGCGCCAGGGGGCGGGGCCAGGCCGGGGTACCGGGAGCGCCCCAAAGGC TTGCGCGCAGGCGCGGCCGCAGGCCTTTGTCCCCCTGACCGGCTTTTTGTCCGCTGTAGG GGAGGGACAGAGTTTGCAGAGGTGGGGCCGACACGTGTGTGCTCTCCAGGCCTGCAGACC CTGGATCATCCTCGGAGTTTGCTGCATTCTGCCCCACGGCGGTTTGGCCAACTACCCACG CACAAAAAAATATATTTCTAAGTTTAACCAACTACCCACACGCTCCAAAAATATTCCAAG CAAAACCACCAACCTGTTCGCAGTGGTTCAAGGAGAGATTTTCCTTTTTAGTTTTTGTGC TTCACCTTTTCTGCACTGTCTGCCTGCCCGTAGTGAGCAGGAATGACTGCTGTAATATCA CAACAAGGCATCTTTCGACGTTAAGGAAAGACGTTATCTTTGGACGTTAAGAATTGTTCT AGAATACATAAATAAAAAATAAAAATGCACAATTCAGTGACATTAGTACATGCACATGTT GGACAACCATCACCCCTTGCTAGTTTCGGGGTATTTTTATCACCCCCAAGAGAGACCCCC GTAGGAGACCAGCATATGCCCCTCTGAAATATGCGACCTTGGTGTAGGATTATTTTGAGC TGAGATCAATGAAGCTGATACCGGAAAAGCTCTCTGTTCTTCCCTGATTTGCCTCAAAGC AGGACCTAAAGGTACAAAGGTGCCCTCCTCCCCTCTCTACCAGGAAGGACAAAGGTTGAT CACCAGGGACACCTTTAGACTCTTGTCTGGAGACGTCTTTTTTTTTTTTTTCTTTTTTTT TGAGACGGAGTCTTGCTCTGTCCCCAAAGCTAGAGTGCAGTAGCGCCATCTCTGCTCACT GCGTCCTCCGCTTCCCTGGTTCAAGCGATTCTCGTGCCTCAGCTTCCCAAGTAGCTGGGA TCACAGCTGTGCACCACTGTGCCCGGCTAATTTTTGTATTTTTGGTAGAGTCGGGGTTTC ACCACGTTGGCCAGGCTGTTCTCAAATTCCTGGCCTCAAGTGATCCGCCCGCCTCGGCCT CCCAAAGTGCTGGGATTACAAGCGTGAGCCACCGCACCCGGCCTCAATGTCCTTTTCCTT CGTCTTGTCACTTCTCCAAAAATTTGCTGCTATATGTTGAAGGTGCTATATAAGCAGGAG TTATATAAGCTATATAAGCCACCTCATTTCTCTTGGCATCTCCCATGTACACATAAGGTA CACATGTTAATAAATTTGTTTTTCCCTTGTTAATTTTTTTTTTTTAGACGGAGCCTCGCT CTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAAGCTCCGCCTCGCG GGTTCACGCCATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGCACTACTACAGGCGCCCGC CACCACGCCTGGGTAATTTTTTTTTTTTTTTTTTTTTTGTATTTTTAGTAGAGACGGGGT TTCACCGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGATCCGCCCGTCTCTGCC TCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCGCGCCTGGCCTCTATTTTTTTTTTTT TTTTTTTTTTTTTTTTTTGAGACAGGGCCTCGCTCTGGGAGGAACCAAATTTGTAGATGT GAAGCCGCCACTTGTGTGCTCTCTGGGCCTGAGGACCCAGGATGATGCCCAGAGCTTGCT ACATTCTGCCCCATGGTAGCTTGACCAACTACCCACAAAAAAGGGGTAGAGTGCAGCGGC ACGATCTTAACTCACTGCAGCCTTGAACTCCTGGGATCAAGCCATCCTGCCACCTCAGCA TCCTGAGTAGGTGGGACCACAGGTGCCTGCCACCACAATTGGCTAATTTCTTTTTATTTT TTATTTTTTGTAGAAATGGAGTCTTACCATGTTACCCAGGCTGGCCTTGAGCCCTGGGCT TAAGCAATCTTCCCACGTCGACCTTCCAAAGTGCTGGAATTACAGGCGTGAACCACCGCA CCCGCCCTTCTTAATTCTTTCATTGCAAGGATCCATCACAGCTAAGAACTAAGAATAAAG GAAAAAGTATGTTTCCTCCCCTACACCCTGTTCCCATAAAGCAATCACTCAATTCCTCCC TCCTCCCAGCCCCTGGCAACCACTAATCTGCATTCTCTGCTGTCTCTCTGTATTTTTACC ACTTCTTGATTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAG ACTGGAGTGCAGTGGCATGATCTCAGCTCACGGCAGCCTCCGCCTCCCAAGTTCAAGCAA TTCTCCTGCCTCGGCCTCCCAAGTGGCTGAGAGTACAGGTGCGCACCACCACACCCGGCT AATTTTTGTATTTGTAGTAGAGATGGATTTTACCATGTTGGCCAGGCTGGTCTTGAACTC TTGACCTCAAGGGATCTGCCTGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGC CACCATGCCCGACCTCCTTGATATTTCATACAAATGGAATCATACAATATGTGACCATTT GTGTCGGCCTCTTCCACCAAGCATAATAGGTTGTTTTGGTTTTTGCTTTTTGTTTTTGAG ACAGGGTCTTGCTGTGTCACCAGGCTGGAGTGCGGTGGTGTGATCATAGCTCACTGCAGC CTTGAACTCCTGGGCCTGAGAGATCCTCCTGCCTCAGCCTCCACATTGCCTGGGACTACA GGTGCACGCCACCACATCTGGCCAATTTTTAAAATTTTTCTTTTGTAGAGATGCGGTCTC GCTATGTTCACCAGGCTGGTTTCGACCTCCTGGACTCAAGGGATCCTCCTGCCTTGGCCT CCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGTGCAGCTGAGCATAATGGTGTTGA GGTTTGTCTAAGTTGCAGCATGTATCAGAAATTCATTCCACTTGCAGCTATATAACATTG CGCCATATGGATGGACCACATTTTGTTTATCCACGTATCAGCTGATGGTCATTTGGGCTG TTTCTGCCTTTTAGCGATCGTGAATAAGTACAGCTATAAACATTTGTGAATATGTAGTTG GAGTCCCTGGATTCCATTCCTTTGGGTCTATACCTAGAAGTGGGGTTGCTGGGTCATTTT GTAACTCTATGTTGAACTTTTTGAGTAATTGCCCAACTGTTTCCCACAGTAGCAGTACCA TTTTCCATCCCCACCAGCATTACACAAAGGTTCCAATTTCGCCACTTCCTTGCAACATCC TTTTTTGATTATGATAGCCATCGTAGTAGGTGTGACGTGCCACCCCATTGTGGTTTTGTT TTGCCTTTTCCTGATGACTAATGATGTCAACGAGTCTGTTTGTTGGTTTGTTTGAATTTT TTTTTTTGAGACAGAGTGTCACTCTATTGCCTAGGCTGGAGTGCAGTGCTGATCTCAGCT CACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCATGCCTCAGCCTCCCAAATAGCT GGGATTACAGCACACCCGCCACTGTGCCCGGCTAATTTTAGACTTTTAGTAGAGACGGGG TTTCGCCATGTTGGCCAGGCTGGTCTCCAACTCCTGATCTCAAGAAATCTGCCCACCTCG GCCTCCCAAAGTGCTGGGATTATAGGCGTGAGTCACCGCGTCTGGCCTCGATGTTAACCA GTTTTCTTTCACAGAATATTTCCTCTTGATTTCAACTCTTGTTACTCTTCTCCTGCATTG CTTTCCTCCTGTTGTTTAAAGTTACAGCAGATTCCTGCCTCAGGAACTTTGCATGTTCTG TTTCCTCTGCAGAAATGTTCTTGAGCCAGATACCAACGTGGCTCCCTCCTTCCCTAACTT CCTTTACTCGAATGTCATCCTCTCACGGGACCCACCCGATCACACCCTCCTGGACACTTC CTACCCATGTTACCTGCTGGTGACCTGTCTTGTTCATGGCTATATCCGCACAGCCTGGCA GAAAACAGAGAATCTGTTTTGTAAGTTTCACTGCCCTGTCCAAAGATCTCTTCTTGTGCT CCAAGGGAGCATGGAACACAAGGGGGCACAAGAAAGGCCTTGTCCACTCCTGTGATTTTC TTCCTCTCTGTCTCTCTCTCTTTCTGTTTTTGTTTTTAAACAGAGTCTCACTCGGTTGCC CAGGCTGGAGTGCAGTGGCATGATTTCGGCTCACTGCCATCTCCACCTCCCGGGTTCAAG CAATTCTCCTGCCTCAGCCTCCCAACCAGCTGGGATTACAGGCACCTGCTACCACGCCCC CACTAATTTTTGGAGTTTTTAATAGAAATAGGGTCTCACCATGTTGGCCAGGCTGGTCTC AAACTCCTGGGCTCAAGTGATCCACCCACTTCGGCCTCCCAAACTGCTGGGATTACAGGC ATGGGCCACCATGCCCAGCCTCTTTTTTTTTTCTTCTTGTTTGTTTTTGAGACAGGGTCT CGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCATAGCACCACTGCTGCATTGAAC TCCTGGGTTCAAGTGATCCTCCATCCTCAGCCTCCCATAGCACTGGGATTACAGGTGTGT GCCACCACACCTGGCCCCAAGAGACTCTTTAACTTCCACATCCAGCTCCTTTTAAGACTT GGGTCCACTGGCTGAGCTCAGTGACTCACACCTGTAATCCCAATACTTTGGGAGGCCAAG GCAGGTGGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAATATGGTGAAACCCC GTCTCAAAAAAAAAAAAAAGACTTGGGTCCACGGGTCTTTGTGCACTCCCCTCTCCCCCA GTGGGGGGGTCACTCTTTTTTTTTTTTTTTAGAGTCAGAGTCTCGCTCTGTCACCCAGGC TGGAATACAGTGGTATGATCTTAGCTCACTGCAACCTCTGCCTCTGGGTTCAAGTGATTC TCCTGCCTCAGCCTCCCAAGTAGCTAGGATTACAGGCACCCACCACCACGCCCAGCTAAT TTTTGTATTTTTAGTAGAGATGGGGTTTTGCCCTGTTGGCCAGGCTGGTCTCGAACTCCT GACCTTGGGGAATCCTCCCATCTCAGCCTCCTAAAGTGCTGGGATTACAGGCATGAGCCA CTGCGCCCAGCCACGGGGTCACTGTTTTCACAGCAGAAAAATTGAAGCCAAGCCAGCTGC AGTGGCCTGTGCCTGTGGTCCCAGCTACTCAGGAGTCTGAGGCACGAGAATCGATTGAAT CCAGGAGGTGGAGGTTGCAGTGAACCGAGATCACGCCACTGCACTCCAGCCTGGGCGTCA GCAAGACCCATCTCTAAAAAAGTAAAACAAAAAAAAATCCAAAGCCAAGGTCCAGACATG CAGAGGAAAGAGGTCACTGGCCGCAAAGCCTGCTGCTGCATGAATAAGCAGATCCCTCCT CTCAGGCCCAAGAGCCTTGGAACAGCGCAATGCATTTGCCCGAATGCTTCCTGTGTGCCG GGTCCCGCTCTAGGCAACAGAGATACAGCAGTGAGCTTTGCAGACACAGCCCAGCCCTCC CAGCGTCCCCCATCTGGCTAGGTCTGAGCTCGACCTTTGAAAAAGACACAGGAGCTGGCC TGGTGTTCACAGCTGGCCTTGGTGTTGCTAGGAGCTGGCCTGGCAGTCAAAGCAGGGCCC TGGTGTCCTCCTGCTGGACATAAACAATCTCACATGACGCCGACATCAGACAAGGCCACT CTGTGACCGCGGCAGAGCAAGACAAAACAAGCCTGCTCCATAATCATGTCTGAACACAGG CAAAACACGAACACTGTCCACACTATCAGAGTAACTGGACCTCCTCTGCTACTAGCTAAT ACCAGCAACGGCTGTTCCTTACCAAGCACAGCTTTAGTCTTCTGACTTCTTTCTTTCTTT CTTTCCTTCCTTCCTTCCCTCCTTCCCCTCCCTCCCTCCTTCCTTCCTTCTTCCTTCCTT TCCCTCCCTCCCTGCTTCCTTCCCTCCTTCTCTCCCTCCCTCCTTCCCTCCTTCTTTCCT TCTTCCTTCCTTTCCCTCCCTTCCTCCCTCCTTCCTTCCCTTCGTCCTTCCTTCCTTCCT TCCAGCTCCCAGCTTCCCTGGAGCTCTAAGGAGGCAGGATTTGCACAAAAAACAAAACCG TGCCCCCAAAACACCTAACAGAACTGCAGATCCCAAATCCCTCCCTCCCTCCCTCCCTCG CTCCCTCCCTTCCTTCCTTCCCTCCCTCTCTCCTTCCTTCCTTCTGACTTCTTCATACAG ATGATTAAGATGCTGAATAATAGTTACTTCTCTCCCTAGCTGCTCTTTTGTTTTGTGTTG TTTCTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGGAATCATAGCT CACTGCACCCTCACTGCAACCTCAATGTCCTGGGTTCAAGAAATCTTCCCACCTTAGCCT CCCAAGTAGCTGGGACTATAGGCACGCGCCACCGCACCTGGCTTTTTAATTTTTTATAGA GATAGGGTCTCACTGTGTTGCCCAGGCTGGTCTCAAACACCTGGGCTCAAGCAGTCCTCC CGCTTCAGCCTCTCAAAGTGATGGGATTACAGGCCTGAGGCACTGCACTCAGCCGCCCTT GCTTCTTTTTTTTTTTTTGAGACAGAGTTTTGCTCTGTGGCCCAAGCTGGAGTGCAGTGG CACGATCTCAGTTCACTGCAACCTCCACCACCTGGGTTCAAGCGATTCTCCTGCCTCAGC CTCCTGAGTAGCTGGGATTACAGGTGCCCGCCACCATGCCCAGCTAGTTTTTTTTTTCTT TGAGACAGAGTTTTGCTCTTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCAGCTCAC TGCAACCTCCGCCTCCTGGGTTCACGCAATTCTCCTGCCTCAGGCTCCTGAGTAGCTGGG AATACAGGTGCCCGCCACCACACCCGGCTATTTTTTATATTTTTAGTAGAGACAGGGTTT CACCATGTTGGCCAGGCTGGCCTCGAACTCCTGACCAAAGGAGATCCGCCTGCCTCAGCC TCCTGAGTAGCGGGGATTACAGGCGTGAGCCACCACGCCCGGCTAATTTTTGTATTTTCA GTAGAGACAGGGTTTCACCGTGTTCGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGAT CCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCAAGCCA CAACAGCCCTTTTCTGGACGCTACTTTGGGAGGCTGAGATTACAAATGTGAGCCACCATG CCTCACCTGTGTGTTGTTTTTATTTGTTTTTATCTGCTCATCTCAAAAAAGAAAGTAAAA TTTCCAACCAATAAATTCATCCCACCCAAATCCCCTACTTCCTTAAGCTGTGCCCCCAAA ACACCGAGCAGAATTGCAAATCCCATAATAAGTGCTTTCTGGCCGGGCGTGGTGGCTCAC GCCTATAATCCCAGCACTTCGGGAGACTGAAGCGAGCGGATCACCCGAGGTCGGCAATTC GAAACCAGCCTGACCAACATGGAAAAACCCCATCTCTACTAAAAATACAAAATTAGCTGG GTGTGGTGGCACATGCCTATAATCCCAGCTACTCGGGAGCCTGAGGCAGGAGAATCACTT GAAGCCGGAGGTTGCGATGAGCTGAGATCGTGCCACTGCACCCCAGCCTGGGCAACAAGA GCGAAACTCCATCTCAAATAAATAAATAAATAAATAAATAGCGAAAAAAAGTTCTTTCTA ACACCTCCCTACTGAGACCGCCATAGTGCCCTATGACATGTATGAGCTCTCTCTCCCTCT CTCTTTCTTTCTCTCTCTCTCTCTGATGAATAATAAGCTTGAATGTGTTCAATCACAGGT ACATTCCTGGTGGTCTTTGACTGGGGAAGGAGGGGTGACCGGCCCCTTTAAAGGGAGATC TGTGAGCCCTAGAATAATATCAAGAGGTGCAGTGATTCAGGGAAGTGGGTCCATTCTGTG TGGGGTGTGTAGAAGGTAGAGGGACAGAAAAACTTTAGAGGATGATAATAATAATGGACA CCAGCAGCCTATTTAATCAAATCCTCAATACTGACACTGCTTTCTGAACTGGCTACCATC ATTAGTCCCCTTTTGCAGATGACAAAACCTAAGTCCTAGCCAGGCATGGTGGCACACACC TGTGGACCCACCCACTTGGGAGGCTGAGGCGAGAGGATCGCTTGAGCCCAGGACTTCAAG TCCAGCCTGGGCAACATAGCGAGAGCTTACCTCAAAAACAAAACCAACCGAACAAAACCC CAGAGGCTCCAAAAAGTCAATTACTTGCCTGGGTTCCTGGAGCTCTAAGGAGGCAGTATT CGCACCAAGCCTGCCTGCTAATTTTCCTCCCGGCT bcftools-1.21/test/csq/ENST00000593942/ENST00000593942.fa.fai000066400000000000000000000000221467060157400215510ustar00rootroot0000000000000019 20615 23 60 61 bcftools-1.21/test/csq/ENST00000593942/ENST00000593942.gff000066400000000000000000000050251467060157400211770ustar00rootroot0000000000000019 ensembl_havana gene 21 20595 . - . ID=gene:ENSG00000104883;Name=PEX11G;biotype=protein_coding;description=peroxisomal biogenesis factor 11 gamma [Source:HGNC Symbol%3BAcc:20208];gene_id=ENSG00000104883;logic_name=ensembl_havana_gene;version=3 19 ensembl_havana transcript 22 20595 . - . ID=transcript:ENST00000593942;Parent=gene:ENSG00000104883;Name=PEX11G-002;biotype=protein_coding;havana_transcript=OTTHUMT00000458966;havana_version=1;tag=basic;transcript_id=ENST00000593942;version=1 19 havana three_prime_UTR 22 347 . - . Parent=transcript:ENST00000593942 19 havana exon 22 582 . - . Parent=transcript:ENST00000593942;Name=ENSE00003214970;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00003214970;rank=7;version=1 19 havana CDS 348 582 . - 1 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 19 havana exon 1460 1522 . - . Parent=transcript:ENST00000593942;Name=ENSE00003562909;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003562909;rank=6;version=1 19 havana CDS 1460 1522 . - 1 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 19 havana exon 5179 5357 . - . Parent=transcript:ENST00000593942;Name=ENSE00003600419;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003600419;rank=5;version=1 19 havana CDS 5179 5357 . - 0 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 19 havana CDS 8984 9022 . - 0 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 19 havana exon 8984 9172 . - . Parent=transcript:ENST00000593942;Name=ENSE00003621789;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003621789;rank=4;version=1 19 havana five_prime_UTR 9023 9172 . - . Parent=transcript:ENST00000593942 19 havana exon 12494 12658 . - . Parent=transcript:ENST00000593942;Name=ENSE00003020804;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003020804;rank=3;version=1 19 havana five_prime_UTR 12494 12658 . - . Parent=transcript:ENST00000593942 19 havana exon 14128 14268 . - . Parent=transcript:ENST00000593942;Name=ENSE00003109739;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003109739;rank=2;version=1 19 havana five_prime_UTR 14128 14268 . - . Parent=transcript:ENST00000593942 19 havana exon 20549 20595 . - . Parent=transcript:ENST00000593942;Name=ENSE00003217935;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003217935;rank=1;version=1 19 havana five_prime_UTR 20549 20595 . - . Parent=transcript:ENST00000593942 bcftools-1.21/test/csq/ENST00000593942/last-codon-deletion.txt000066400000000000000000000002611467060157400232640ustar00rootroot00000000000000349 CA C stop_lost&frameshift|PEX11G|ENST00000593942|protein_coding|-|172*>172D|349CA>C 349 CA C stop_lost&frameshift|PEX11G|ENST00000593942|protein_coding|-|172*>172D|349CA>C bcftools-1.21/test/csq/ENST00000593942/last-codon-deletion.vcf000066400000000000000000000007541467060157400232320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 19 349 . CA C . . EXP=stop_lost&frameshift|PEX11G|ENST00000593942|protein_coding|-|172*>172D|349CA>C;type=ENST00000593942:7542089-CA-C, deletion in the last codon, tr.ref needs context bcftools-1.21/test/csq/ENST00000624631/000077500000000000000000000000001467060157400166465ustar00rootroot00000000000000bcftools-1.21/test/csq/ENST00000624631/ENST00000624631.fa000066400000000000000000000026431467060157400210020ustar00rootroot00000000000000>7 7:65140428-65141823 TACAAAGCATCATAAAGTATGATTTGCAGACATATTTTATAAATTGGAACACCTTAAGGA TTCATGGCATTTGTGTAAAATGTGTGGTCGTTAACACATTTTAATACATTGATTCTATTG TGGAAGGTCGTGTGACATGGAATGTTAAACAATTAAAATGGTCAAATGTACTTCCATGTT TATGTGATTTGCATTCACAGGAAGAAAATGGGTAATGCCGAAGGAACATTGGCCTAGAGA AGCTTACTGAAGCAAGGGAATTTGGAGTGAGACTTTCTCCCGCTGCGGCTTTCTGCCCCC ACACCGCGGCTTTTGCAGCTTTTTGCCTCCGCTGCCGCGGCGTTTTGGTCCCCGCCGCCG CGGCTTTTTGTGGTTTTTTTGCCCCAGCTCCCACTGCTTTTTGTCCCCCCCGCCGCGGCT TTTTGCCCCCGCCCCGGCGGCTTTCTTCCGCCGCGGCTTTTTGCCCCGCCGCCGCGCATT TTTGCCGCCGCGGCTTTTTGCCCCCGCCGCCTAAGCTTTTTGCCTGCGCCGCCGCGGCTT TTTGCCCCCCGTCGCCGCGGCTTTTTGCCGCCGCGGCTTTCTGCTCCCGCCGCCACGGCT CTGAGGGCGGGAGCGGCAGACTCCGCTGCCAGCTCTACTGGCGTCCTGGCAAGGGCAGCG CCGAGGGGCGCTCCCGGTCCAGCTCTCCCGGCTCGGGGGTTCCTTGCCTAGGCGCCAGAG CCCCGGGCTCCCTGCCTCGGCCGCTGTGGCCTGCATAGAGCGGCACTGCGCGCGGAGGCG ATGGGAGAGAAGAAGGAGGGCGGTGGCGGGGGTGATGCAGCGGCCGCTGAGGGTGGCGCA GGGGCCCCGGCCAGCCCGGGGCTGCAGCAGTGCAGACAGCTCCAGAAGCTCATCGGCATC TCCATTGGCAGCCTGCGCGGGCTGGGCACCAAGTGCGCTGTGTCCAACGACCTCACCGAG CAGGAGATACGGACCCTGGAGGTAAGGGGTTTGGGGACCCGGGCTGGGCTCGAGGAGCGG CCCGGACACCTCCCTTGAGGCCCCAGTTCACTCCTGGCCGAGTTGCATCCTTGAGCCCGC GTCGCGCCCTTGGAGGCTTCCCCTCCCTCCTGCACTCGCTGATGGGGCAGCCGAGAGACC CGGGACCAGCCCTCACCTTGGGCAGGATTTGTGGGGCGAGTGCTTGGTGGGAACTGGGAT GGAGGCTCTAGGGTCCCGTGGGGCGGGGAGGGTGGGGGTGGGCTGCGCGCGGACATCCCC TTACCCCCGAATTTCCATCTGGTCCGGCCCTCTCATCTTGTAGGTGAGGAAACCAAAGGC CTGAGGGAGAACTGACTTGCCAGGAACCCCTGTTAAGGAGAATTACCAAAGTGTGGTTAT TAAAGGAGAACTGAGT bcftools-1.21/test/csq/ENST00000624631/ENST00000624631.fa.fai000066400000000000000000000000201467060157400215230ustar00rootroot000000000000007 1396 23 60 61 bcftools-1.21/test/csq/ENST00000624631/ENST00000624631.gff000066400000000000000000000023061467060157400211520ustar00rootroot000000000000007 ensembl gene 101 1296 . - . ID=gene:ENSG00000280410;Name=AC104073.1;biotype=protein_coding;gene_id=ENSG00000280410;logic_name=ensembl;version=1 7 ensembl mRNA 101 1296 . - . ID=transcript:ENST00000624631;Parent=gene:ENSG00000280410;Name=AC104073.1-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000624631;transcript_support_level=5;version=1 7 ensembl exon 101 544 . - . Parent=transcript:ENST00000624631;Name=ENSE00003758654;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003758654;rank=3;version=1 7 ensembl CDS 101 544 . - 0 ID=CDS:ENSP00000485644;Parent=transcript:ENST00000624631;protein_id=ENSP00000485644 7 ensembl exon 547 975 . - . Parent=transcript:ENST00000624631;Name=ENSE00003759678;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003759678;rank=2;version=1 7 ensembl CDS 547 975 . - 0 ID=CDS:ENSP00000485644;Parent=transcript:ENST00000624631;protein_id=ENSP00000485644 7 ensembl exon 1264 1296 . - . Parent=transcript:ENST00000624631;Name=ENSE00003757286;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003757286;rank=1;version=1 7 ensembl CDS 1264 1296 . - 0 ID=CDS:ENSP00000485644;Parent=transcript:ENST00000624631;protein_id=ENSP00000485644 bcftools-1.21/test/csq/ENST00000624631/ambiguous.txt000066400000000000000000000011331467060157400214000ustar00rootroot00000000000000547 CCC CC frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC,splice_region|AC104073.1|ENST00000624631|protein_coding 547 CCC CC frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC,splice_region|AC104073.1|ENST00000624631|protein_coding bcftools-1.21/test/csq/ENST00000624631/ambiguous.vcf000066400000000000000000000012201467060157400213340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 7 547 . CCC CC . . type=ENST00000624631:65140974-CCC-CC;EXP=splice_region|AC104073.1|ENST00000624631|protein_coding,frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC bcftools-1.21/test/csq/ENST00000624631/ascii-art.txt000066400000000000000000000002021467060157400212550ustar00rootroot00000000000000 547 iiieeeeeeeeee... TTTTGCCCCCCGTCGCCGCGG TTTTGCCC-CCGTCGC iiieeeeeeeeee... TTTTG-CCCCCGTCGC TTTTGCCCCC-GTCGC bcftools-1.21/test/csq/make-csq-test000077500000000000000000000257051467060157400174440ustar00rootroot00000000000000#!/usr/bin/env perl # # Author: petr.danecek@sanger # use strict; use warnings; use Carp; use FindBin; $ENV{PATH} = $FindBin::RealBin."/../../:$ENV{PATH}"; my $opts = parse_params(); parse_gff($opts); create_ref($opts); create_vcf($opts,0); create_vcf($opts,$$opts{offset}); create_gff($opts,0); create_gff($opts,$$opts{offset}); run_vep($opts); run_bcsq($opts,$$opts{offset}); run_bcsq($opts,0); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "Usage: make-csq-test [OPTIONS]\n", "Options:\n", " -f, --fasta-ref \n", " -g, --gff \n", " -i, --indels introduce indels\n", " -o, --output \n", " -p, --position \n", " --pad [20]\n", " -t, --transcript \n", " -h, -?, --help This help message.\n", "\n", "Example:\n", " ./make-csq-test -f \$ref -g \$gff -o rmme -p 3566625-AGCAGGCTG-A -t ENST00000378322\n", "\n"; exit -1; } sub parse_params { my $opts = { indels=>0, pad=>20 }; while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '--pad' ) { $$opts{pad}=shift(@ARGV); next; } if ( $arg eq '-p' || $arg eq '--position' ) { push @{$$opts{pos}},shift(@ARGV); next; } if ( $arg eq '-i' || $arg eq '--indels' ) { $$opts{indels}=shift(@ARGV); next; } if ( $arg eq '-f' || $arg eq '--fasta-ref' ) { $$opts{ref}=shift(@ARGV); next; } if ( $arg eq '-t' || $arg eq '--transcript' ) { push @{$$opts{tscript}},shift(@ARGV); next; } if ( $arg eq '-g' || $arg eq '--gff' ) { $$opts{gff}=shift(@ARGV); next; } if ( $arg eq '-o' || $arg eq '--output' ) { $$opts{out}=shift(@ARGV); next; } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } if ( !exists($$opts{ref}) ) { error("Missing the -f option.\n") } if ( !exists($$opts{gff}) ) { error("Missing the -g option.\n") } if ( !exists($$opts{out}) ) { error("Missing the -o option.\n") } if ( !exists($$opts{tscript}) ) { error("Missing the -t option.\n") } for my $tscript (@{$$opts{tscript}}) { $$opts{tscripts}{$tscript} = 0; } return $opts; } sub parse_gff { my ($opts) = @_; my $ntscript = 0; my @buf = (); my $cmd = ($$opts{gff} =~ /\.gz$/i) ? "gunzip -c $$opts{gff}" : "cat $$opts{gff}"; open(my $fh,"$cmd |") or error("$cmd: $!"); while (my $line=<$fh>) { if ( $line=~/^###/ ) { @buf = (); next; } if ( $line=~/^#/ ) { next; } my @vals = split(/\t/,$line); push @buf,\@vals; if ( !($vals[8]=~/ID=transcript:([^;]+);/) ) { next; } my $tscript = $1; if ( !exists($$opts{tscripts}{$tscript}) ) { next; } $$opts{tscripts}{$tscript} = ++$ntscript; if ( $ntscript==scalar keys %{$$opts{tscripts}} ) { last; } } if ( $ntscript!=scalar keys %{$$opts{tscripts}} ) { my @missing = (); for my $tscript (keys %{$$opts{tscripts}}) { if (!$$opts{tscripts}{$tscript}) { push @missing,$tscript; } } error("Transcript(s) not found in $$opts{gff}: ".join(",",@missing)."\n"); } if ( !($buf[-1][8]=~/Parent=gene:([^;\s+]+)/) ) { error("Gene ID not present: $buf[-1][8]\n"); } my $gene_id = $1; while (my $line=<$fh>) { if ( $line=~/^###/ ) { last; } my @vals = split(/\t/,$line); push @buf,\@vals; } my $tline; my @dat = (); my ($chr,$beg_min,$end_max); for my $line (@buf) { if ( $$line[8]=~/ID=gene:$gene_id/ ) { push @dat,$line; next; } if ( $$line[8]=~/ID=transcript:([^;]+)/ ) { my $tscript = $1; if ( exists($$opts{tscripts}{$tscript}) ) { push @dat,$line; if ( !defined $chr ) { $chr = $$line[0]; } if ( !defined $beg_min or $beg_min > $$line[3] ) { $beg_min = $$line[3]; } if ( !defined $end_max or $end_max < $$line[4] ) { $end_max = $$line[4]; } $tline = $line; } next; } if ( $$line[8]=~/Parent=transcript:([^;]+)/ ) { my $tscript = $1; if ( exists($$opts{tscripts}{$tscript}) ) { push @dat,$line; } next; } if ( $$line[8]=~/Parent=transcript:$$opts{tscript}/ ) { push @dat,$line; next; } } close($fh); $$opts{dat} = \@dat; $$opts{offset} = $beg_min - $$opts{pad} - 1; # pos_new = pos_ori - offset $$opts{tchr} = $chr; $$opts{tbeg} = $beg_min; $$opts{tend} = $end_max; } sub get_type { my ($rec) = @_; if ( $$rec[2] eq 'gene' ) { return $$rec[2]; } if ( $$rec[2] eq 'transcript' ) { return $$rec[2]; } if ( $$rec[2] eq 'exon' ) { return $$rec[2]; } if ( $$rec[2] eq 'CDS' ) { return $$rec[2]; } if ( $$rec[2] eq 'three_prime_UTR' ) { return $$rec[2]; } if ( $$rec[2] eq 'five_prime_UTR' ) { return $$rec[2]; } error("Unknown type: $$rec[2] .. ".join("\t",@$rec)); } sub get_strand { my ($rec) = @_; return $$rec[6]; } sub create_ref { my ($opts) = @_; my $chr = $$opts{tchr}; my $beg = $$opts{tbeg} - $$opts{pad}; my $end = $$opts{tend} + $$opts{pad}; my $ref = ''; open(my $out,'>',"$$opts{out}.fa") or error("$$opts{out}.fa: $!"); open(my $fh,"samtools faidx $$opts{ref} $chr:$beg-$end|") or error("samtools faidx $$opts{ref} $chr:$beg-$end: $!"); <$fh>; print $out ">$chr\t$chr:$beg-$end\n"; while (my $line=<$fh>) { print $out $line; chomp($line); $ref .= $line; } close($fh); close($out); $$opts{refseq} = $ref; `rm -f $$opts{out}.fai; samtools faidx $$opts{out}.fa`; } sub create_vcf { my ($opts,$offset) = @_; my $strand = get_strand($$opts{dat}[0]); my $chr = $$opts{tchr}; my $beg0 = $$opts{tbeg} - $$opts{pad}; my $end0 = $$opts{tend} + $$opts{pad}; my %dat; if ( exists($$opts{pos}) ) { for my $pos_ref_alt (@{$$opts{pos}}) { my ($pos,$ref,$alt) = split(/-/,$pos_ref_alt); $dat{$pos}{ref} = $ref; $dat{$pos}{alt} = $alt; push @{$dat{$pos}{type}}, join('-',@{$$opts{tscript}}).":$pos_ref_alt"; } } else { # unused. If used, get_chr_beg_end() needs fixing # for my $dat (@{$$opts{dat}}) # { # my ($chr,$beg,$end) = get_chr_beg_end($dat); # my $type = get_type($dat); # for my $off (-9,-8,-4,-3,-2,0,2,3,4,8,9) # { # my $pos = $beg + $off; # if ( $pos<$beg0 or $pos>$end0 ) { next; } # if ( $$opts{indels} == 0 ) # { # $dat{$pos}{ref} = substr($$opts{refseq},$pos-$beg0,1); # $dat{$pos}{alt} = $dat{$pos}{ref} eq 'A' ? 'C' : 'A'; # } # elsif ( $$opts{indels} > 0 ) # { # $dat{$pos}{ref} = substr($$opts{refseq},$pos-$beg0,1); # $dat{$pos}{alt} = $dat{$pos}{ref}. ('A' x $$opts{indels}); # } # else # { # if ( $pos-$beg0-$$opts{indels} > length($$opts{refseq}) ) { next; } # $dat{$pos}{ref} = substr($$opts{refseq},$pos-$beg0,-$$opts{indels}); # $dat{$pos}{alt} = substr($$opts{refseq},$pos-$beg0,1); # } # push @{$dat{$pos}{type}}, "$type:$off"; # } # } } my $fname = $offset ? "$$opts{out}.vcf" : "$$opts{out}.vcf.ori"; open(my $out,'>',"$fname") or error("$fname: $!"); print $out qq[##fileformat=VCFv4.2\n]; print $out qq[##contig=\n]; print $out qq[##INFO=\n]; print $out qq[##INFO=\n]; print $out qq[##INFO=\n]; print $out "#".join("\t", qw(CHROM POS ID REF ALT QUAL FILTER INFO))."\n"; for my $pos (sort {$a<=>$b} keys %dat) { my $ref = $dat{$pos}{ref}; my $alt = $dat{$pos}{alt}; my $type = join(',',@{$dat{$pos}{type}}); printf STDERR "offset=$offset .. $pos %d\n",$pos-$offset; print $out join("\t",($chr,$pos-$offset,'.',$ref,$alt,'.','.',"type=$type"))."\n"; } close($out); } sub create_gff { my ($opts,$offset) = @_; my $fname = $offset ? "$$opts{out}.gff" : "$$opts{out}.gff.ori"; open(my $out,'>',"$fname") or error("$fname: $!"); for my $dat (@{$$opts{dat}}) { my (@x) = (@$dat); $x[3] -= $offset; $x[4] -= $offset; print $out join("\t",@x); } close($out); } sub run_vep { my ($opts) = @_; my $vep = "perl -I /software/vertres/installs/ensembl/82/ /software/vertres/bin-external/variant_effect_predictor_v82.pl --db_version 82 -t SO --format vcf --force_overwrite --cache --dir /lustre/scratch116/vr/ref/ensembl/vep_cache/ --species human --offline --symbol --biotype --vcf --no_stats --assembly GRCh37 --no_progress --quiet -o -"; my $cmd = "cat $$opts{out}.vcf.ori | $vep | bcftools query -f'%POS\\t%REF\\t%ALT\\t%CSQ\\n'"; open(my $fh,"$cmd |") or error("$cmd: $!"); open(my $out,'>',"$$opts{out}.vep.txt") or error("$$opts{out}.vep.txt: $!"); while (my $line=<$fh>) { my @out = (); my ($pos,$ref,$alt,$csq) = split(/\t/,$line); my @csq = split(/,/,$csq); chomp($csq[-1]); for my $csq (@csq) { if ( $csq=~/Transcript\|$$opts{tscript}/ ) { push @out,$csq; } } if ( !scalar @out ) { @out = ('.'); } $csq = join(',',@out); print $out join("\t",($pos,$ref,$alt,$csq))."\n"; } close($fh); close($out); } sub run_bcsq { my ($opts,$offset) = @_; my $fname = $offset ? "$$opts{out}.bcsq.txt" : "$$opts{out}.bcsq.txt.ori"; my $vcf = $offset ? "$$opts{out}.vcf" : "$$opts{out}.vcf.ori"; my $gff = $offset ? "$$opts{out}.gff" : $$opts{gff}; my $ref = $offset ? "$$opts{out}.fa" : $$opts{ref}; my $cmd = "bcftools csq -f $ref -g $gff $vcf | bcftools query -f'%POS\\t%REF\\t%ALT\\t%BCSQ\\n'"; print STDERR "$cmd\n"; open(my $fh,"$cmd |") or error("$cmd: $!"); open(my $out,'>',$fname) or error("$fname: $!"); while (my $line=<$fh>) { my @out = (); my ($pos,$ref,$alt,$csq) = split(/\t/,$line); my @csq = split(/,/,$csq); chomp($csq[-1]); for my $csq (@csq) { if ( !($csq=~/Transcript/) or $csq=~/Transcript\|$$opts{tscript}/ ) { push @out,$csq; } } if ( !scalar @out ) { @out = ('.'); } $csq = join(',',@out); print $out join("\t",($pos,$ref,$alt,$csq))."\n"; } close($fh); close($out); } bcftools-1.21/test/csq/make-csq-test-by-region000077500000000000000000000113241467060157400213250ustar00rootroot00000000000000#!/usr/bin/env perl # # Author: petr.danecek@sanger # use strict; use warnings; use Carp; use FindBin; $ENV{PATH} = $FindBin::RealBin."/../../:$ENV{PATH}"; my $opts = parse_params(); create_gff($opts); create_ref($opts); create_vcf($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "Usage: make-csq-test [OPTIONS]\n", "Options:\n", " -f, --fasta-ref \n", " -g, --gff \n", " -o, --output \n", " -r, --region \n", " -v, --vcf \n", " -h, -?, --help This help message.\n", "\n", "Example:\n", " ./make-csq-test -f ref.fa -g file.gff -v file.vcf -o rmme -r 19:10026674-10027069\n", "\n"; exit -1; } sub parse_params { my $opts = { indels=>0, pad=>20 }; while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '-f' || $arg eq '--fasta-ref' ) { $$opts{ref}=shift(@ARGV); next; } if ( $arg eq '-g' || $arg eq '--gff' ) { $$opts{gff}=shift(@ARGV); next; } if ( $arg eq '-o' || $arg eq '--output' ) { $$opts{out}=shift(@ARGV); next; } if ( $arg eq '-v' || $arg eq '--vcf' ) { $$opts{vcf}=shift(@ARGV); next; } if ( $arg eq '-r' || $arg eq '--region' ) { $$opts{region}=shift(@ARGV); next; } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } if ( !exists($$opts{ref}) ) { error("Missing the -f option.\n") } if ( !exists($$opts{out}) ) { error("Missing the -o option.\n") } if ( !exists($$opts{vcf}) ) { error("Missing the -v option.\n") } if ( !exists($$opts{region}) ) { error("Missing the -r option.\n") } return $opts; } sub create_gff { my ($opts) = @_; if ( !($$opts{region}=~/^([^:]+):(\d+)-(\d+)$/) ) { error("Could not parse the region: $$opts{region}"); } my $chr = $1; my $beg = $2; my $end = $3; if ( !exists($$opts{gff}) ) { $$opts{chr} = $chr; $$opts{end} = $end; $$opts{offset} = $beg; return; } my @buf = (); my $cmd = ($$opts{gff} =~ /\.gz$/i) ? "gunzip -c $$opts{gff}" : "cat $$opts{gff}"; open(my $fh,"$cmd |") or error("$cmd: $!"); while (my $line=<$fh>) { if ( $line=~/^#/ ) { next; } my @vals = split(/\t/,$line); if ( $vals[0] ne $chr ) { next; } if ( $vals[4] < $beg ) { next; } if ( $vals[3] > $end ) { last; } if ( $vals[8]=~/ID=gene:([^;]+);/ ) { if ( $vals[3] < $beg ) { $beg = $vals[3]; } if ( $vals[4] > $end ) { $end = $vals[4]; } } push @buf,\@vals; } $$opts{offset} = $beg - 100; my $fname = "$$opts{out}.gff"; open(my $out,'>',"$fname") or error("$fname: $!"); for my $line (@buf) { $$line[3] -= $$opts{offset}; $$line[4] -= $$opts{offset}; print $out join("\t",@$line); } close($out) or error("close failed: $$opts{out}.gff"); $$opts{chr} = $chr; $$opts{end} = $end; } sub create_ref { my ($opts) = @_; my $chr = $$opts{chr}; my $beg = $$opts{offset} + 1; my $end = $$opts{end}; my $ref = ''; open(my $out,'>',"$$opts{out}.fa") or error("$$opts{out}.fa: $!"); open(my $fh,"samtools faidx $$opts{ref} $chr:$beg-$end|") or error("samtools faidx $$opts{ref} $chr:$beg-$end: $!"); <$fh>; print $out ">$chr\t$chr:$beg-$end\n"; while (my $line=<$fh>) { print $out $line; chomp($line); $ref .= $line; } close($fh); close($out); } sub create_vcf { my ($opts,$offset) = @_; my $chr = $$opts{chr}; my $fname = "$$opts{out}.vcf"; open(my $out,'>',"$fname") or error("$fname: $!"); open(my $in,'<',$$opts{vcf}) or error("$$opts{vcf}: $!"); print $out qq[##fileformat=VCFv4.2\n]; print $out qq[##contig=\n]; print $out qq[##INFO=\n]; print $out qq[##INFO=\n]; print $out qq[##INFO=\n]; print $out "#".join("\t", qw(CHROM POS ID REF ALT QUAL FILTER INFO))."\n"; while (my $line=<$in>) { if ( $line=~/^#/ ) { next; } my @col = split(/\t/,$line); my $chr = $col[0]; my $pos = $col[1]; my $ref = $col[3]; my $alt = $col[4]; my $flt = $col[6]; print $out join("\t",($chr,$pos-$$opts{offset},'.',$ref,$alt,'.',$flt,'.'))."\n"; } close($out); close($in); } bcftools-1.21/test/csq/sort-csq000077500000000000000000000032501467060157400165300ustar00rootroot00000000000000#!/usr/bin/env perl # # Author: petr.danecek@sanger # use strict; use warnings; use Carp; my $opts = parse_params(); sort_csq($opts); exit; #-------------------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "Usage: sort-csq [OPTIONS]\n", "Options:\n", " -q, --query-output Sort not a VCF but `bcftools query` output\n", " -h, -?, --help This help message.\n", "\n"; exit -1; } sub parse_params { my $opts = {}; while (defined(my $arg=shift(@ARGV))) { if ( $arg eq '-q' || $arg eq '--query' ) { $$opts{query} = 1; next; } if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } error("Unknown parameter \"$arg\". Run -h for help.\n"); } return $opts; } sub sort_csq { my ($opts) = @_; while (my $line=) { if ( $line=~/^#/ ) { print $line; next; } chomp($line); if ( $$opts{query} ) { $line = sort_comma_separated_fields($line); } else { $line = sort_csq_tag($line,'EXP'); $line = sort_csq_tag($line,'BCSQ'); } print $line."\n"; } } sub sort_csq_tag { my ($line,$tag) = @_; if ( !($line=~/$tag=([^;\t]+)/) ) { return $line; } my $beg = $`; my $end = $'; my $hit = $1; my @vals = sort split(/,/,$hit); return $beg."$tag=".join(',',@vals).$end; } sub sort_comma_separated_fields { my ($line) = @_; my @out = (); for my $col (split(/\s+/,$line)) { my @tmp = sort split(/,/,$col); push @out,join(',',@tmp); } return join("\t",@out); } bcftools-1.21/test/dosage.1.out000066400000000000000000000002411467060157400163700ustar00rootroot00000000000000#[1]CHROM [2]POS [3]REF [4]ALT [5]A [6]B 1 3000150 C T 0.111816 -1.000000 1 3000151 C G 0.000251 -1.000000 1 3000152 C T,G 0.000251,0.000251 -1.000000,-1.000000 bcftools-1.21/test/dosage.2.out000066400000000000000000000002411467060157400163710ustar00rootroot00000000000000#[1]CHROM [2]POS [3]REF [4]ALT [5]A [6]B 1 3000150 C T 0.111816 -1.000000 1 3000151 C G 0.000244 -1.000000 1 3000152 C T,G 0.000244,0.000244 -1.000000,-1.000000 bcftools-1.21/test/dosage.3.out000066400000000000000000000001711467060157400163740ustar00rootroot00000000000000#[1]CHROM [2]POS [3]REF [4]ALT [5]A [6]B 1 3000150 C T 0.0 -1.0 1 3000151 C G 0.0 -1.0 1 3000152 C T,G 0.0,0.0 -1.0,-1.0 bcftools-1.21/test/dosage.vcf000066400000000000000000000012731467060157400162060ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS . GT:PL:GL 0/0:0,9,95:0,-0.9,-9.5 . 1 3000151 . C G 59.2 PASS . GT:PL:GL 0/0:0,36,545:-0.00031839,-3.6121,-54.5012 . 1 3000152 . C T,G 59.2 PASS . GT:PL:GL 0/0:0,36,545,36,545,545:-0.00031839,-3.6121,-54.5012,-3.6121,-54.5012,-54.5012 . bcftools-1.21/test/empty.idx.out000066400000000000000000000000001467060157400167010ustar00rootroot00000000000000bcftools-1.21/test/empty.idx_count.out000066400000000000000000000000021467060157400201130ustar00rootroot000000000000000 bcftools-1.21/test/empty.vcf000066400000000000000000000004201467060157400160730ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##contig= ##contig= ##contig= ##reference=file://some/path/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 bcftools-1.21/test/ex1.gtf.gz000066400000000000000000000073021467060157400160610ustar00rootroot00000000000000‹ÿBC{ í]oÛ8†¯½¿"Èí"¿9s•™é´À¶I¦3—Am€©SÄé`÷ß/)ɱ$‹)JžD>*£ ÃÔ_žò¼ýú‹·gŸÞ~üåÃâóÕåS J Y¼YüÛþý²\-¯ïm£wÄý¡”E>zz¼Y­oï¿?m\ ¸ŒjÛ øÙ§ÿ}_|xZÞ¯®oîîW_6ß[?Ý<ýXÿçìüϳÍW7ßì\^œ0~ì 4—§ÃZ‹v·µoív~B‰û-ÿ^þuÄ~>úzó÷ÍêæÚýWŽŽÏ¯®ÞþX¾oûÇHÛô_·ufËÿ>¬Z"´mß%:N•@tAtïOÿ8=;-ðä1k5xÌžyÑT^åðÔŠ-ÀЬáIóú±²]Þ.×ëåÝõ÷õòÇ݃ûáÁÜNI#·i±ísÓîªjF5ç¶ÝÃÊ~çâÝùOåWE z}x;ôL0†è÷‚¾Ð;%œf»#„ž+¹ B"ô‰¡×£Õ ºæ=ÄG«-=„ šé5¦âèN3©ŒX2jƒ]„¾7“Z@ç„Z‡x“ZBÃ,6Ť2Sƒ=ŽnûŸ||r\,|;À©{”1AÁöŒò_ûT1£Ü ³(fΛpJå¾kçMN<ƒ\QdÆ´ <“ÙŸ§ŸÞ‹‹Ñi•ÝZN,š“Ð~NÒÐ N” ™;¥75§x=ír*¼‚Ú#¨¹¼ÚDe -ÂÖ~xÍU_õÅš ªÕàÅ‚ŠŽhwEµ~zø¾‰J© îA1ÂJˆ° f˜z&¤žœJµàLò Û¥5p5Ù%é|¶aNÚ^n '/§Â78aáOPÔþ@Íuä5¢:-u.'Œ1zc ç „´Á…PUÁ…wì6AáØõyÍ’“‚Î FPªÏŒÁ Aœ3P6¹F™ì6@¡3𥚒+²’jTÐi69¡/ð<µGPsyõèb N]DERZHSÍž±Û…c×ë5…\N‡á Tœ3:ƒ¨Í Š¹PÀqÍÀ?vÓ,9Yè4Ã6® f(†#/ì Æà„Î ¥ÐE3[Ÿ0ÌÖÍU™ Ÿœn•‰œ|ùâÀÝCæ¸ÂÍKçD38Õ‡_×ÀPcæ¸JÏP€’D ®¼ ¶½–¸Ü¡=8{ì:µÕ@?')²9D¨ß…9Q@PfËiØ2åܪ L® æ ª‘;ŽÀ sǨU%¥”^(C³ ÁiŽÁé|Aƒú¿/h€B_0)¨¹[¨ñ@ÍÔD5¢‹8at]h`°Ðnã?zÍ×Üp2……m\:ƒiAÍtäÕÁœÐDÕ¬hW]€’ìwJÉ…v{8Ñ„m\Ê°¬BÏ™ƒZ×κ´šBaE,|[DuÕo¨€Kö©HN|?÷IŒâ2© )³{!5ó0¡¼ÍgTs~#¢šûøÕL`ã6­QHaò˜t^»‹68ÆQžT…î!†”%vqÞQ¥Š ÒÞ ©¹FÝÃEµTsUU#Ž5Ìà¡ÄƱMØ®JŒ!åÙî°9ãZ„`+ÆÄî9åŸíOE ?ý ©bļ‘vuš}û Nµ¼‰ÏIàÎÝ‚5%&t)²ÎÚu·¥¬)ºÕàUQN"Üu=10bŸ‚åèSªÍk#×ðð£é³}ÇAÍlXT)²ö²nD]ÖìPcŸLJ?f „™h¦[Q×·û˳Ó®_×7'ßîOì§MOhÛMO)0wzÝÄ[M…=ÌDÐjðÚ4†Ü!j¡}ÿ¼Ê6ð€xŠ² ¿1ÌÛet Ó+n*Œò"–„Rq¦$°dPŒæNZü~ú˜>õ°>kQõ›vù/‰DJ;…»aÊg!ÓX¦eŒS15<°¶ägÚjð‚™&ñôæy´PM²µ3Wœ¥„š½ì\ F²±d]QŸƒÉkæi¾ @´}², ËÜö0ÓÜiK6>*&˶âkX`Uù¦ñ-pRnç~n4©Æ Á£|–ÐÎg Ø@‰HeZ2E›:¢Mm’E0N:°­u&@¡! m1%%$!¨Öl¤õSœ îY­ tË”‘¢PÅË”‚á»s©iLŸ'9;—G²°n»n•suÝìÚÒ-²ÃRL°U@¸* Y2VƒÄ £–äe"™•F #Â¥aryµ;7; ¥y‚).`·$òhŸÓÝÆrˆÎ·qA,Õ Á”-Ÿ&ƒe¦Œu<êuº},Î/ù;€éj«þ‚< FÄyŒ‘mOñoáÕ3Q·L€:oZßl. r‚,.×î².ûÌK”²n5@šQ :w×Òø]t*2Ç ½¶ ?Ý|9:þÕFPö‹··wk÷fÜ?ņð'À#?ΙŸŠ·1 ÷´¼K{›Ç»Õà…òŽ·<`sQ™ûRf}¾Ò™^^<¥7Eì£`w)s…Û”G`!îIUþœp9ÞÆ=+Û‚Ô'£^un4åû ꔡlÆX Ñ„˜Pº"%gd‡wVa´ñ ­0Ú$”Ÿ[Ê2’r 5,Yewƒ ìá°‹¸¹ÂLÖêÇÜjðª0'!î²ÅívÆ@¨‚ßÜ&a„P2ÜÙùo?xÈñ¥n,‚ 5‘óÔœ07±Ì¨Vã 9hœË×\‹‘w6™4I"­¢.2±¤;·=“6B|œŸt«Á "Ý_çRü†xÊ^ë›ËÕÚ¯ÖÊ.P© ß.b†ØßZ­ eY ¤Û»uÊ®xKi÷D¼+eKê沘d*Y éñH£µžÜZKAZi4Ýœ"ãJrå^Tp¢t01‘»¨×«Ë³Óëa%0º‹rG‡ƒ´¬ûgÎÆÒjð*°x‘Ô;ê¥g‰€o TÒð1ú¤,¢jc‰`ñ¹óžÌÍO§¼ñÏ2zp {³­/õÍvË~–ŸoÃû bUï^DàØPë}… çÉõÈ+ g©/à}ÿ*HùD‹ÿBC)íÚÑnÚ0àëì)Pn§Vö±}l«Wˆu«´–J+í.QQ‹ÔYµ½ýìÐ$M‚†dÔ6*=uÂ×ÓÛJü{Õó¿ïý«^¼ ¢Õd9[Äã(øöüþ-‚dD_R¸BMÉkø¾öàª÷¼Q0~#Sw?Ý<Þ}#ëþ¦â}Ьn”ÖIŠÚ¿ú4yYRï¦ÿÔö=;œG1ç4Ê”ò.½ÏæÓþ`<›öüëáÃú<À©Ðzûª÷$¿ÿ]˜ ],ç“pµ §¹ËÊ*Vqç5’'w¶OxpÔ\]qìCÒµ”·ôÞGmn¸þ#q\©ó3EÏ6ˆ¾öï(%ƒÛí±êl ¥ã^mÒ8xîùƒÁ—óäd2]Ùd¿5kdžÛÚ%·{j@“30R OZ{c~ ±ykæ¹EL*L•/|kòÉÆ]f®ä‡¦Pð›W ìÌs75€MS£ùà:5ݦïPVK¬RBùÿ~ê Z€ómËwÓ¹´yçRx&²Õuµd‹™Pè\úñu¾û|Wñ|a_xÒ¿HTnLܬ ËY9A‚ pä/;(¢Ý`»o€I3 ÎInUáòãÍ\0w+¹NÍÍÕ.ãìíÒ 3×î§mwTDº)`»SÀõ>³’µ9hMhùr ´eRê–Íh—Ý(·9Aå}fë,e%g¾ãœleÎ0¹[£¶s¡à¬œk—- ºN=Ö©ëD0A€Ü9·ìü“x 4Õ/‹ÿBCbcftools-1.21/test/ex2.vcf000066400000000000000000000032751467060157400154460ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 20 14370 rs6054257 G A 29.1 . 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T . 47 PASS NS=3;DP=13;AA=T GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 ./. 20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9;AA=G GT:GQ:DP 0/1:35:4 0/2:17:2 1/1:40:3 bcftools-1.21/test/ex3.sam000066400000000000000000000014321467060157400154420ustar00rootroot00000000000000@SQ SN:ref LN:45 @SQ SN:ref2 LN:40 r001 163 ref 7 30 8M4I4M1D3M = 37 39 TTAGATAAAGAGGATACTG * XX:B:S,12561,2,20,112 YY:i:100 r002 0 ref 9 30 1S2I6M1P1I1P1I4M2I * 0 0 AAAAGATAAGGGATAAA * XA:Z:abc XB:i:-10 r003 0 ref 9 30 5H6M * 0 0 AGCTAA * r004 0 ref 16 30 6M14N1I5M * 0 0 ATAGCTCTCAGC * r003 16 ref 29 30 6H5M * 0 0 TAGGC * r001 83 ref 37 30 9M = 7 -39 CAGCGCCAT * x1 0 ref2 1 30 20M * 0 0 aggttttataaaacaaataa * x2 0 ref2 2 30 21M * 0 0 ggttttataaaacaaataatt ????????????????????? x3 0 ref2 6 30 9M4I13M * 0 0 ttataaaacAAATaattaagtctaca ?????????????????????????? x4 0 ref2 10 30 25M * 0 0 CaaaTaattaagtctacagagcaac ????????????????????????? x5 0 ref2 12 30 24M * 0 0 aaTaattaagtctacagagcaact ???????????????????????? x6 0 ref2 14 30 23M * 0 0 Taattaagtctacagagcaacta ??????????????????????? bcftools-1.21/test/fill-AN-AC.out000066400000000000000000000050001467060157400164700ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS AN=0;AC=0 GT:GQ ./.:245 ./.:245 1 3000151 . C T 59.2 PASS AN=0;AC=0 GT:DP:GQ ./.:32:245 ./.:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS AN=0;AC=0 GT:GQ:DP ./.:245:32 ./.:245:32 1 3106154 . C CT 59.2 PASS AN=0;AC=0 GT:GQ:DP ./.:245:32 ./.:245:32 1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS AN=0;AC=0 GT:GQ:DP ./.:212:22 ./.:212:22 1 3177144 . G T 45 PASS AN=0;AC=0 GT:GQ:DP ./.:150:30 ./.:150:30 1 3177144 . G . 45 PASS AN=0 GT:GQ:DP ./.:150:30 ./.:150:30 1 3184885 . TAAAA TA,T 61.5 PASS AN=0;AC=0,0 GT:GQ:DP ./.:12:10 ./.:12:10 2 3199812 . G GTT,GT 82.7 PASS AN=0;AC=0,0 GT:GQ:DP ./.:322:26 ./.:322:26 3 3212016 . CTT C,CT 79 PASS AN=0;AC=0,0 GT:GQ:DP ./.:91:26 ./.:91:26 4 3258448 . TACACACAC T 59.9 PASS AN=0;AC=0 GT:GQ:DP ./.:325:31 ./.:325:31 bcftools-1.21/test/fill-tags-AD.1.out000066400000000000000000000010041467060157400172700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C chr1 10153 . AC A . . AD=3,1;DP=66 AD 10,1 20,2 30,3 chr1 10153 . AC A . . AD=3,1;DP=11 AD 10,1 . . bcftools-1.21/test/fill-tags-AD.2.out000066400000000000000000000010031467060157400172700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C chr1 10153 . AC A . . AD=3,1;DP=4 AD 10,1 20,2 30,3 chr1 10153 . AC A . . AD=3,1;DP=4 AD 10,1 . . bcftools-1.21/test/fill-tags-AD.3.out000066400000000000000000000010271467060157400172770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C chr1 10153 . AC A . . AD=3,1 AD:DP 10,1:11 20,2:22 30,3:33 chr1 10153 . AC A . . AD=3,1 AD:DP 10,1:11 .:. .:. bcftools-1.21/test/fill-tags-AD.4.out000066400000000000000000000011621467060157400173000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##INFO= ##INFO=10)"> #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C chr1 10153 . AC A . . AD=3,1;XX=1;YY=2 AD 10,1 20,2 30,3 chr1 10153 . AC A . . AD=3,1;XX=1;YY=0 AD 10,1 . . bcftools-1.21/test/fill-tags-AD.vcf000066400000000000000000000005271467060157400171110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C chr1 10153 . AC A . . AD=3,1 AD 10,1 20,2 30,3 chr1 10153 . AC A . . AD=3,1 AD 10,1 . . bcftools-1.21/test/fill-tags-AN0.out000066400000000000000000000042351467060157400172340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMP_A SAMP_B SAMP_C SAMP_E chr1 10146 . AC A . PASS NS=2;AN=4;AF=0.5;AC=2;F_MISSING=0.5;MAF=0.5;AC_Het=2;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=0.666667;END=10147;TYPE=INDEL GT ./. 0/1 ./. 0/1 chr1 10153 . A C . PASS NS=0;AN=0;AF=.;AC=0;F_MISSING=1;MAF=.;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1;END=10153;TYPE=SNP GT ./. ./. ./. ./. chr1 10154 . C G . PASS NS=0;AN=0;AF=.;AC=0;F_MISSING=1;MAF=.;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1;END=10154;TYPE=SNP GT ./. ./. ./. ./. chr1 10172 . C A . PASS NS=3;AN=6;AF=0;AC=0;F_MISSING=0.25;MAF=0;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1;END=10172;TYPE=SNP GT 0/0 0/0 0/0 ./. bcftools-1.21/test/fill-tags-AN0.vcf000066400000000000000000000015031467060157400171760ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMP_A SAMP_B SAMP_C SAMP_E chr1 10146 . AC A . PASS NS=3;AN=6;AF=0.5;AC=3 GT ./. 0/1 ./. 0/1 chr1 10153 . A C . PASS NS=1;AN=2;AF=0.5;AC=2 GT ./. ./. ./. ./. chr1 10154 . C G . PASS NS=2;AN=4;AF=0.25;AC=1 GT ./. ./. ./. ./. chr1 10172 . C A . PASS NS=3;AN=6;AF=0;AC=0 GT 0/0 0/0 0/0 ./. bcftools-1.21/test/fill-tags-VAF.out000066400000000000000000000010731467060157400172670ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 10153 . AC A,C,G . . . AD:VAF:VAF1 1,1,1,1:0.25,0.25,0.25:0.75 chr1 10153 . AC A,C,G . . . AD . bcftools-1.21/test/fill-tags-VAF.vcf000066400000000000000000000004071467060157400172360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 10153 . AC A,C,G . . . AD 1,1,1,1 chr1 10153 . AC A,C,G . . . AD . bcftools-1.21/test/fill-tags-func.out000066400000000000000000000013471467060157400176120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 S5 S6 S7 S8 S9 S10 1 3177144 . G T 45 PASS XX=0 GT 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T 45 PASS XX=0.2 GT 1/0 1/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T 45 PASS XX=0.1 GT 1/1 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T,C 45 PASS XX=1 GT 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 bcftools-1.21/test/fill-tags-hemi.1.out000066400000000000000000000037431467060157400177420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3177144 . G T,A 45 PASS F_MISSING=0;NS=2;AN=2;AF=0.5,0.5;MAF=0.5;AC=1,1;AC_Het=0,0;AC_Hom=0,0;AC_Hemi=1,1;HWE=1,1;ExcHet=1,1 GT 1 2 1 3177144 . G T 45 PASS F_MISSING=1;NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=1;HWE=1;ExcHet=1 GT 0/. 1/. 1 3177144 . G T 45 PASS F_MISSING=1;NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=1;HWE=1;ExcHet=1 GT ./0 ./1 1 3177144 . G T 45 PASS F_MISSING=1;NS=1;AN=1;AF=1;MAF=0;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=1;HWE=1;ExcHet=1 GT ./. ./1 bcftools-1.21/test/fill-tags-hemi.2.out000066400000000000000000000037431467060157400177430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3177144 . G T,A 45 PASS F_MISSING=0;NS=2;AN=2;AF=0.5,0.5;MAF=0.5;AC=1,1;AC_Het=0,0;AC_Hom=0,0;AC_Hemi=1,1;HWE=1,1;ExcHet=1,1 GT 1 2 1 3177144 . G T 45 PASS F_MISSING=1;NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1 GT 0/. 1/. 1 3177144 . G T 45 PASS F_MISSING=1;NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1 GT ./0 ./1 1 3177144 . G T 45 PASS F_MISSING=1;NS=1;AN=1;AF=1;MAF=0;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1 GT ./. ./1 bcftools-1.21/test/fill-tags-hemi.vcf000066400000000000000000000006341467060157400175460ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3177144 . G T,A 45 PASS . GT 1 2 1 3177144 . G T 45 PASS . GT 0/. 1/. 1 3177144 . G T 45 PASS . GT ./0 ./1 1 3177144 . G T 45 PASS . GT ./. ./1 bcftools-1.21/test/fill-tags-hwe.out000066400000000000000000000042531467060157400174410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 S5 S6 S7 S8 S9 S10 1 3177144 . G T 45 PASS F_MISSING=0;NS=10;AN=20;AF=0;MAF=0;AC=0;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=1 GT 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T 45 PASS F_MISSING=0;NS=10;AN=20;AF=0.1;MAF=0.1;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0;HWE=1;ExcHet=0.947368 GT 1/0 1/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T 45 PASS F_MISSING=0;NS=10;AN=20;AF=0.1;MAF=0.1;AC=2;AC_Het=0;AC_Hom=2;AC_Hemi=0;HWE=0.0526316;ExcHet=1 GT 1/1 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T,C 45 PASS F_MISSING=0;NS=10;AN=20;AF=0.5,0;MAF=0.5;AC=10,0;AC_Het=10,0;AC_Hom=0,0;AC_Hemi=0,0;HWE=0.00690641,1;ExcHet=0.00554244,1 GT 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 bcftools-1.21/test/fill-tags-hwe.vcf000066400000000000000000000010731467060157400174050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 S5 S6 S7 S8 S9 S10 1 3177144 . G T 45 PASS . GT 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T 45 PASS . GT 1/0 1/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T 45 PASS . GT 1/1 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 0/0 1 3177144 . G T,C 45 PASS . GT 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 1/0 bcftools-1.21/test/fill-tags.2.out000066400000000000000000000140211467060157400170120ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=100223;NS=3;AN=6 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0;NS=0;AN=0;AF=.;MAF=.;AC=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;NS=3;AN=6;AF=0.833333;MAF=0.166667;AC=5 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2;NS=3;AF=0.333333,0.333333;MAF=0.333333 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2;NS=2;AF=0.5;MAF=0.5 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1;NS=3;AF=0.25;MAF=0.25 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1;NS=3;AF=0.25;MAF=0.25 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3;NS=3;AF=0.75;MAF=0.25 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=2;NS=3;AF=0.5;MAF=0.5 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1;NS=2;AF=0.5;MAF=0.5 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2;NS=2;AF=1;MAF=0 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. bcftools-1.21/test/fill-tags.3.out000066400000000000000000000135041467060157400170200ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0;AC_AB=0;AC_BC=0;AC=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;AC_AB=3;AC_BC=4;AC=5 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2;AC_AB=1,1;AC_BC=2,1 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2;AC_AB=2;AC_BC=1 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1;AC_AB=0;AC_BC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1;AC_AB=0;AC_BC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3;AC_AB=1;AC_BC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=2;AC_AB=1;AC_BC=2 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1;AC_AB=1;AC_BC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2;AC_AB=2;AC_BC=1 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. bcftools-1.21/test/fill-tags.3.smpl000066400000000000000000000000441467060157400171570ustar00rootroot00000000000000NA00001 AB NA00002 AB,BC NA00003 BC bcftools-1.21/test/fill-tags.4.out000066400000000000000000000022751467060157400170240ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A C,AA,AAA,AAAA,AAAAA,AAAAAA,AAAAAAA,AAAAAAAA,AAAAAAAAA,AAAAAAAAAA,AAAAAAAAAAA,AAAAAAAAAAAA,AAAAAAAAAAAAA,AAAAAAAAAAAAAA,AAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 999 . AN=6;AC=1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1 GT 0/1 2/3 33/34 bcftools-1.21/test/fill-tags.5.out000066400000000000000000000136021467060157400170210ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=586;DP_AB=404;DP_BC=393 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0;DP_AB=0;DP_BC=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=586;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;DP_AB=404;DP_BC=393 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=306;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4;DP_AB=228;DP_BC=189 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=203;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4;DP_AB=137;DP_BC=137 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=247;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4;DP_AB=169;DP_BC=160 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=131;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2;DP_AB=84;DP_BC=98 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=163;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4;DP_AB=103;DP_BC=73 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=228;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2;DP_AB=228;DP_BC=111 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=9;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1;DP_AB=5;DP_BC=7 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=138;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1;DP_AB=76;DP_BC=99 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=105;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3;DP_AB=53;DP_BC=85 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=105;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3;DP_AB=53;DP_BC=85 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=111;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1;DP_AB=111;DP_BC=64 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=276;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2;DP_AB=276;DP_BC=130 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. bcftools-1.21/test/fill-tags.out000066400000000000000000000062101467060157400166530ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ 0/1:245 0/1:245 1 3000151 . C T 59.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1;AC_Het=1,0;AC_Hom=0,0;AC_Hemi=0,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3106154 . C CT 59.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3157410 . GA G 90.6 q10 AN=4;AC=4;AC_Het=0;AC_Hom=4;AC_Hemi=0 GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:212:22 0/1:212:22 1 3177144 . G T 45 PASS AN=4;AC=2;AC_Het=0;AC_Hom=2;AC_Hemi=0 GT:GQ:DP 0/0:150:30 1/1:150:30 1 3177144 . G . 45 PASS AN=4 GT:GQ:DP 0/0:150:30 0/0:150:30 1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2;AC_Het=2,2;AC_Hom=0,0;AC_Hemi=0,0 GT:GQ:DP 1/2:12:10 1/2:12:10 2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2;AC_Het=2,2;AC_Hom=0,0;AC_Hemi=0,0 GT:GQ:DP 1/2:322:26 1/2:322:26 3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2;AC_Het=2,2;AC_Hom=0,0;AC_Hemi=0,0 GT:GQ:DP 1/2:91:26 1/2:91:26 4 3258448 . TACACACAC T . PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:325:31 0/1:325:31 bcftools-1.21/test/filter-missing-floats.vcf000066400000000000000000000035241467060157400211670ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##contig= ##FORMAT= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 201 . A T 0 PASS A_AF=0.00008;B_AF=0.00008;C_AF=0.00008 1 202 . A T 0 PASS A_AF=0.00008 1 203 . A T 0 PASS A_AF=0.00008;B_AF=0.00008; 1 204 . A T 0 PASS A_AF=0.00008;C_AF=0.00008 1 205 . A T 0 PASS B_AF=0.00008 1 206 . A T 0 PASS B_AF=0.00008;C_AF=0.00008 1 207 . A T 0 PASS C_AF=0.00008 1 301 . A T 0 PASS A_AF=0.00008;B_AF=0.00008;C_AF=0.00012 1 302 . A T 0 PASS A_AF=0.00008; 1 303 . A T 0 PASS A_AF=0.00008;B_AF=0.00008; 1 304 . A T 0 PASS A_AF=0.00008;C_AF=0.00012 1 305 . A T 0 PASS B_AF=0.00008 1 306 . A T 0 PASS B_AF=0.00008;C_AF=0.00012 1 307 . A T 0 PASS C_AF=0.00012 1 401 . A T 0 PASS A_AF=0.00008;B_AF=0.00012;C_AF=0.00008 1 402 . A T 0 PASS A_AF=0.00008; 1 403 . A T 0 PASS A_AF=0.00008;B_AF=0.00012 1 404 . A T 0 PASS A_AF=0.00008;C_AF=0.00008 1 405 . A T 0 PASS B_AF=0.00012 1 406 . A T 0 PASS B_AF=0.00012;C_AF=0.00008 1 407 . A T 0 PASS C_AF=0.00008 1 501 . A T 0 PASS A_AF=0.00012;B_AF=0.00008;C_AF=0.00008 1 502 . A T 0 PASS A_AF=0.00012; 1 503 . A T 0 PASS A_AF=0.00012;B_AF=0.00008 1 504 . A T 0 PASS A_AF=0.00012;C_AF=0.00008 1 505 . A T 0 PASS B_AF=0.00008 1 506 . A T 0 PASS B_AF=0.00008;C_AF=0.00008 1 507 . A T 0 PASS C_AF=0.00008 1 1001 . A T 0 PASS A_AF=0.00012;B_AF=0.00012;C_AF=0.00012 1 1002 . A T 0 PASS A_AF=0.00012; 1 1003 . A T 0 PASS A_AF=0.00012;B_AF=0.00012 1 1004 . A T 0 PASS A_AF=0.00012;C_AF=0.00012 1 1005 . A T 0 PASS B_AF=0.00012 1 1006 . A T 0 PASS B_AF=0.00012;C_AF=0.00012 1 1007 . A T 0 PASS C_AF=0.00012 bcftools-1.21/test/filter.1.out000066400000000000000000000037471467060157400164310ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= ##contig= ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 1000 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1003 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1007 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2000 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2003 . T TC 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2006 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1001 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1008 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2001 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2006 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 bcftools-1.21/test/filter.1.vcf000066400000000000000000000044041467060157400163670ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= ##contig= ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 1000 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1001 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1003 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1006 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1007 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2000 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2001 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2003 . T TC 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2005 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2006 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1001 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1004 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1008 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2001 . A AT 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2003 . A AT 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2006 . A AT 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 bcftools-1.21/test/filter.10.out000066400000000000000000000012521467060157400164760ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##contig= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 chr1 1 . A T 100 PASS TEST1=10;TEST2=10 GT:TEST3:TEST4 0/1:10:10 ./.:30:30 chr1 2 . A T 100 PASS TEST1=50;TEST2=50 GT:TEST3:TEST4 0/1:20:20 ./.:40:40 bcftools-1.21/test/filter.10.vcf000066400000000000000000000006661467060157400164550ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SMPL 1 1100 . T G . . . GT:AD:DP 1/1:5,6:12 1 1101 . T G . . . GT:AD:DP 1/1:5,6:10 bcftools-1.21/test/filter.11.out000066400000000000000000000032021467060157400164740ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:25:300 1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:25:12 0/1:245:310 1 3157410 . 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CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:25:300 1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:25:12 0/1:245:310 1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:212:22 1 3177144 . G T 45 PASS AN=4;AC=2 GT:GQ:DP 0/0:150:30 1/1:150:30 1 3177144 . G . 45 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:20 2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:20 1/2:322:10 3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 4 3258448 . 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GAA G,GA 238 q20 DP=19;AN=4;AC=1,1;XRF=1e6,2e6,3e6;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e6,2e6;XAI=1111,2222;XAS=ABC,DEF;XGF=1e6,2e6,3e6,4e6,5e6,6e6;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 q20 AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:1e-1,2e-2,3e-3,4e-4,5e-5,6e-6:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 2:AAAAAA,BBB,C:1,2,3:1e-1,2e-2,3e-3:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 bcftools-1.21/test/filter.30.out000066400000000000000000000006251467060157400165030ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/dummy.fas ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 chr1 251 . C T 68 . . 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T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2001 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2003 . T TC 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2005 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2006 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1001 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1004 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1008 . GT G 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2001 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2003 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2006 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 bcftools-1.21/test/filter.41.out000066400000000000000000000046361467060157400165130ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= ##contig= ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 1000 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1001 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1003 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1006 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1007 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2000 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2001 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2003 . T TC 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2005 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2006 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1001 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1004 . GT G 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1008 . GT G 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2001 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2003 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2006 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 bcftools-1.21/test/filter.42.out000066400000000000000000000046371467060157400165150ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= ##contig= ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 1000 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1001 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1003 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1006 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1007 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2000 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2001 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2003 . T TC 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2005 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2006 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1001 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1004 . GT G 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1008 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2001 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2003 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2006 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 bcftools-1.21/test/filter.43.out000066400000000000000000000046221467060157400165100ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= ##contig= ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 1000 . G A 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1001 . G A 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1003 . GT G 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1006 . G A 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 1007 . G A 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2000 . T C 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2001 . T C 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2003 . T TC 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2005 . T C 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 2006 . T C 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1001 . GT G 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1004 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 1008 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2001 . A AT 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2003 . A AT 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 2 2006 . A AT 1806 xxx DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 bcftools-1.21/test/filter.5.out000066400000000000000000000000561467060157400164230ustar00rootroot000000000000003162006 q20;XX 19 0/1 0/2 3162007 q20 . 0/1 2 bcftools-1.21/test/filter.5.vcf000066400000000000000000000013411467060157400163700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3162007 . A C . . . DP:AD:FR:SR 1:1,11:1,11:1a,11b . . 1 3162007 . A C . . . DP:AD:FR:SR . 2:2,11:2,11:2a,11b . 1 3162007 . A C . . . DP:AD:FR:SR . . 3:3,11:3,11:3a,11b bcftools-1.21/test/filter.6.out000066400000000000000000000000531467060157400164210ustar00rootroot000000000000003162006 XX 19 0/1 0/2 3162007 PASS . 0/1 2 bcftools-1.21/test/filter.6.vcf000066400000000000000000000004751467060157400164000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D E 1 3162007 . A C . . . GT 0/0 ./. 0/1 0/0 0/0 bcftools-1.21/test/filter.7.out000066400000000000000000000000571467060157400164260ustar00rootroot000000000000003162006 q20;XX 19 0/1 0/2 3162007 PASS . 0/1 2 bcftools-1.21/test/filter.7.vcf000066400000000000000000000011161467060157400163720ustar00rootroot00000000000000##fileformat=VCFv4.3 ##reference=file://ref.fa ##INFO= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1000 . G A . . . 1 1001 . G A . . . 1 1003 . GG G . . . 1 1006 . G A . . . 1 1007 . G A . . . 2 1000 . G A . . . 2 1001 . G A . . . 2 1003 . G . . END=1004 2 1006 . G A . . . 2 1007 . G A . . . 3 1000 . G A . . . 3 1001 . G A . . . 3 1003 . GG AA . . . 3 1006 . G A . . . 3 1007 . G A . . . bcftools-1.21/test/filter.8.out000066400000000000000000000000221467060157400164170ustar00rootroot000000000000003177144 2 0/0 1/1 bcftools-1.21/test/filter.8.vcf000066400000000000000000000005411467060157400163740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/dummy.fas ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 chr1 251 . C T 68 . . GT:AO 0/1:3,4 0/0:2,4,5 0/1:3,4,5 bcftools-1.21/test/filter.9.out000066400000000000000000000000221467060157400164200ustar00rootroot000000000000003177144 0 0/0 0/0 bcftools-1.21/test/filter.9.vcf000066400000000000000000000006271467060157400164020ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162007 . A C 110 . AD=11,22 AD 1,2 10,20 bcftools-1.21/test/filter.string.1.1.out000066400000000000000000000010671467060157400200660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample chr1 11558105 . G C . PASS DP=61;TAG=Example TAG Example bcftools-1.21/test/filter.string.1.txt000066400000000000000000000000221467060157400177250ustar00rootroot00000000000000Example Something bcftools-1.21/test/filter.string.1.vcf000066400000000000000000000012141467060157400176700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample chr1 11558102 . G GT . PASS DP=61 . . chr1 11558105 . G C . PASS DP=61;TAG=Example TAG Example chr1 11558108 . A T . PASS DP=61;TAG=It TAG It bcftools-1.21/test/fixploidy.out000066400000000000000000000023051467060157400170010ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000001 xx C CT 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR .:11:1.1:xxx 0:11:1.1:x 0|0:11:1.1:x 1 3000002 . C CTT . . . GT ././. ./././. .|.|.|.|. 1 3000003 xx C CTTT 11 q11 FLAG;IINT=.;IFLT=.;ISTR=. GT:FINT:FFLT:FSTR 0/0:.:.:. 0/0:.:.:. 0|0:.:.:. 1 3000004 xx C CTTTT 11 q11 FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0/0/0/0/0:11:1.1:x 0/0/0/0/0/0/0:11:1.1:xxx 0|0|0|0|0|0|0|0:11:1.1:xxx bcftools-1.21/test/fixploidy.ploidy000066400000000000000000000003301467060157400174660ustar00rootroot000000000000001 3000001 3000001 X 0 1 3000001 3000001 Y 1 1 3000001 3000001 Z 2 1 3000002 3000002 X 3 1 3000002 3000002 Y 4 1 3000002 3000002 Z 5 1 3000004 3000004 X 6 1 3000004 3000004 Y 7 1 3000004 3000004 Z 8 bcftools-1.21/test/fixploidy.samples000066400000000000000000000000141467060157400176310ustar00rootroot00000000000000A X B Y C Z bcftools-1.21/test/fixploidy.vcf000066400000000000000000000021531467060157400167510ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000001 xx C CT 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:11:1.1:xxx 0/0:11:1.1:x 0|0:11:1.1:x 1 3000002 . C CTT . . . GT ./. ./. .|. 1 3000003 xx C CTTT 11 q11 FLAG;IINT=.;IFLT=.;ISTR=. GT:FINT:FFLT:FSTR 0/0:.:.:. 0/0:.:.:. 0|0:.:.:. 1 3000004 xx C CTTTT 11 q11 FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:11:1.1:x 0/0:11:1.1:xxx 0|0:11:1.1:xxx bcftools-1.21/test/fixref.1.out000066400000000000000000000026461467060157400164240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . T G,A 999 PASS . GT 1/2 1/2 2 1 . G ACGT 999 PASS . GT 1/0 1/0 2 101 . A C 999 PASS . GT 0/0 0/0 2 114 . TC TTCC,TTC 999 PASS . GT 1/2 1/2 2 115 . C T 999 PASS . GT 1/1 1/1 20 3 . G CT 999 PASS . GT 0/1 0/1 20 3 . GATG GACT 999 PASS . GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . GT 1/2 1/2 20 59 . AG . 999 PASS . GT 0/0 0/0 20 80 . CACAG CACAT 999 PASS . GT 0/1 0/1 20 81 . A C 999 PASS . GT 0/1 0/1 20 95 . TCACCG ACACCG 999 PASS . GT 0/1 0/1 20 95 . TCACCG AAAAAA 999 PASS . GT 0/1 0/1 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS . GT 1/2 1/2 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. 20 275 . A C,G 999 PASS . GT 2 2 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . GT ./. ./. 3 15 . CACA CAC 999 PASS . GT ./. ./. 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS . GT ./. ./. 5 22 . A AGA 999 PASS . GT ./. ./. bcftools-1.21/test/fixref.2.out000066400000000000000000000011051467060157400164120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 1 1 rs1 C T . . FIXREF=none GT 0/1 1 2 rs2 T A . . FIXREF=swap GT 0/1 1 3 rs3 A T . . FIXREF=none GT 0/1 1 4 rs4 A T . . FIXREF=swap GT 0/1 1 5 rs5 C T . . FIXREF=none GT 0/1 1 6 rs6 C T . . FIXREF=swap GT 0/1 bcftools-1.21/test/fixref.2a.vcf000066400000000000000000000005741467060157400165330ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 1 1 rs1 C T . . . GT 0/1 1 2 rs2 A T . . . GT 1/0 1 3 rs3 A T . . . GT 0/1 1 4 rs4 T A . . . GT 1/0 1 5 rs5 C T . . . GT 0/1 1 6 rs6 T C . . . GT 1/0 bcftools-1.21/test/fixref.2b.vcf000066400000000000000000000005131467060157400165250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 rs1 C T . . . 1 2 rs2 T G . . . 1 3 rs3 A T,C . . . 1 4 rs4 A T,C . . . 1 5 rs5 C A,T . . . 1 6 rs6 C A,T . . . bcftools-1.21/test/fixref.3.fa000066400000000000000000000003101467060157400161670ustar00rootroot00000000000000>1 ACGGGGACAGATATGTTAACT >2 ATGAGTGAATCAAGCACTATT >3 AAATTCAGATACAGAATCTTT >4 GATGGACAGGATGACCTCTAG >5 GGTTAAATGTCAAGGTGAGCT >6 ATGCTAATAAAACATTAAAGT >7 ATGAGAAAGTCTGAGAGTGCA >8 CTACATGACTCTTTATGTTAC bcftools-1.21/test/fixref.3.out000066400000000000000000000014011467060157400164120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 1 11 rs1535632 A T . . FIXREF=flip,swap,GT GT 1/1 2 11 rs363334 C G . . FIXREF=none GT 0/0 3 11 rs7101540 A T . . FIXREF=none GT 0/0 4 11 rs7113791 A T . . FIXREF=flip,swap,GT GT 1/1 5 11 rs778833 C G . . FIXREF=flip,swap,GT GT 1/1 6 11 rs4933195 A T . . FIXREF=none GT 0/0 7 11 rs903997 C G . . FIXREF=none GT 0/0 8 11 rs1942968 C G . . FIXREF=flip,swap,GT GT 1/1 bcftools-1.21/test/fixref.3.vcf000066400000000000000000000010041467060157400163600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 1 11 rs1535632 A T . . . GT 0/0 2 11 rs363334 C G . . . GT 0/0 3 11 rs7101540 A T . . . GT 0/0 4 11 rs7113791 A T . . . GT 0/0 5 11 rs778833 C G . . . GT 0/0 6 11 rs4933195 A T . . . GT 0/0 7 11 rs903997 C G . . . GT 0/0 8 11 rs1942968 C G . . . GT 0/0 bcftools-1.21/test/fixref.4.out000066400000000000000000000011051467060157400164140ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 1 1 rs1 C T . . FIXREF=none GT 0/1 1 2 rs2 T A . . FIXREF=swap GT 1/0 1 3 rs3 A T . . FIXREF=none GT 0/1 1 4 rs4 A T . . FIXREF=swap GT 1/0 1 5 rs5 C T . . FIXREF=none GT 0/1 1 6 rs6 C T . . FIXREF=swap GT 1/0 bcftools-1.21/test/fixref.5.out000066400000000000000000000011101467060157400164110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 1 1 rs1 C T . . FIXREF=none GT 0/1 1 2 rs2 A T . . FIXREF=skip GT 1/0 1 3 rs3 A T . . FIXREF=skip GT 0/1 1 4 rs4 T A . . FIXREF=skip GT 1/0 1 5 rs5 C T . . FIXREF=none GT 0/1 1 6 rs6 C T . . FIXREF=swap,GT GT 0/1 bcftools-1.21/test/fixref.6.out000066400000000000000000000011161467060157400164200ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 1 1 rs1 C T . . FIXREF=none GT 0/1 1 2 rs2 T A . . FIXREF=swap,GT GT 0/1 1 3 rs3 A T . . FIXREF=none GT 0/1 1 4 rs4 A T . . FIXREF=swap,GT GT 0/1 1 5 rs5 C T . . FIXREF=none GT 0/1 1 6 rs6 C T . . FIXREF=swap,GT GT 0/1 bcftools-1.21/test/fixref.7.out000066400000000000000000000011051467060157400164170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FORMAT= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 1 1 rs1 C T . . FIXREF=none GT 0/1 1 2 rs2 T A . . FIXREF=swap GT 1/0 1 3 rs3 A T . . FIXREF=none GT 0/1 1 4 rs4 A T . . FIXREF=swap GT 1/0 1 5 rs5 C T . . FIXREF=none GT 0/1 1 6 rs6 C T . . FIXREF=swap GT 1/0 bcftools-1.21/test/fixref.vcf000066400000000000000000000027421467060157400162310ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . T G,A 999 PASS . GT 1/2 1/2 2 1 . G ACGT 999 PASS . GT 1/0 1/0 2 101 . C A 999 PASS . GT 1/1 1/1 2 114 . TC TTCC,TTC 999 PASS . GT 1/2 1/2 2 115 . T C 999 PASS . GT 0/0 0/0 20 3 . G CT 999 PASS . GT 0/1 0/1 20 3 . GATG GACT 999 PASS . GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . GT 1/2 1/2 20 59 . AG . 999 PASS . GT 0/0 0/0 20 80 . CACAG CACAT 999 PASS . GT 0/1 0/1 20 81 . A C 999 PASS . GT 0/1 0/1 20 95 . TCACCG ACACCG 999 PASS . GT 0/1 0/1 20 95 . TCACCG AAAAAA 999 PASS . GT 0/1 0/1 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS . GT 1/2 1/2 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. 20 275 . A C,G 999 PASS . GT 2 2 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . GT ./. ./. 3 15 . CACA CAC 999 PASS . GT ./. ./. 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS . GT ./. ./. 5 22 . A AGA 999 PASS . GT ./. ./. bcftools-1.21/test/gtcheck.1.2.out000066400000000000000000000000361467060157400167000ustar00rootroot00000000000000DCv2 s1 s1 0 0.000000e+00 2 0 bcftools-1.21/test/gtcheck.1.gts.vcf000066400000000000000000000007701467060157400173100ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 11 33 . C A . PASS . GT:PL 0|0:0,10,20 11 33 . C T . PASS . GT:PL 0|1:10,0,10 bcftools-1.21/test/gtcheck.1.out000066400000000000000000000000361467060157400165400ustar00rootroot00000000000000DCv2 s1 s1 0 3.465736e-01 2 2 bcftools-1.21/test/gtcheck.1.vcf000066400000000000000000000007701467060157400165140ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 11 33 . C T . PASS . GT:PL 0|1:10,0,10 11 33 . C A . PASS . GT:PL 0|0:0,10,20 bcftools-1.21/test/gtcheck.10.out000066400000000000000000000000511467060157400166150ustar00rootroot00000000000000DCv2 s1 s1 0.000000e+00 3.465736e-01 2 2 bcftools-1.21/test/gtcheck.11.out000066400000000000000000000000511467060157400166160ustar00rootroot00000000000000DCv2 s1 s1 0.000000e+00 3.465736e-01 2 2 bcftools-1.21/test/gtcheck.12.out000066400000000000000000000006061467060157400166250ustar00rootroot00000000000000DCv2 B A 5.733631e-01 1.126897e+00 2 2 DCv2 C A 4.938053e+00 8.675006e-01 2 1 DCv2 C B 2.791391e+00 8.675006e-01 2 1 DCv2 D A 5.022610e+00 0.000000e+00 2 0 DCv2 D B 5.178533e+00 0.000000e+00 2 0 DCv2 D C 4.938053e+00 0.000000e+00 2 0 DCv2 E A 7.325195e+00 0.000000e+00 2 0 DCv2 E B 5.178533e+00 0.000000e+00 2 0 DCv2 E C 2.635468e+00 1.386294e+00 2 1 DCv2 E D 2.720025e+00 7.133499e-01 2 1 bcftools-1.21/test/gtcheck.2.out000066400000000000000000000000361467060157400165410ustar00rootroot00000000000000DCv2 s1 s1 0 6.931472e-01 1 1 bcftools-1.21/test/gtcheck.2.vcf000066400000000000000000000007211467060157400165110ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 11 33 . C T . PASS . GT:PL 0|1:10,0,10 bcftools-1.21/test/gtcheck.3.1.out000066400000000000000000000001651467060157400167040ustar00rootroot00000000000000DCv2 A D 2.302585e+00 0.000000e+00 1 0 DCv2 A E 4.605170e+00 0.000000e+00 1 0 DCv2 D E 2.302585e+00 0.000000e+00 1 0 bcftools-1.21/test/gtcheck.3.out000066400000000000000000000004301467060157400165400ustar00rootroot00000000000000DCv2 B A 0 1.126897e+00 2 2 DCv2 C A 1 8.675006e-01 2 1 DCv2 C B 1 8.675006e-01 2 1 DCv2 D A 2 0.000000e+00 2 0 DCv2 D B 2 0.000000e+00 2 0 DCv2 D C 2 0.000000e+00 2 0 DCv2 E A 2 0.000000e+00 2 0 DCv2 E B 2 0.000000e+00 2 0 DCv2 E C 1 1.386294e+00 2 1 DCv2 E D 1 7.133499e-01 2 1 bcftools-1.21/test/gtcheck.3.pairs000066400000000000000000000000741467060157400170530ustar00rootroot00000000000000B A C A C B D A D B D C E A E B E C E D bcftools-1.21/test/gtcheck.3.vcf000066400000000000000000000011371467060157400165140ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D E 11 33 . C T . PASS . GT:PL 0/0:0,10,20 0/0:0,10,10 1/1:20,10,0 0/1:20,0,10 1/1:20,10,0 11 34 . C T . PASS . GT:PL 0/1:10,0,20 0/1:10,0,10 0/1:20,0,20 1/1:20,10,0 1/1:20,10,0 bcftools-1.21/test/gtcheck.4.out000066400000000000000000000001241467060157400165410ustar00rootroot00000000000000DCv2 D C 2 0.000000e+00 2 0 DCv2 E C 1 1.386294e+00 2 1 DCv2 E D 1 7.133499e-01 2 1 bcftools-1.21/test/gtcheck.4.pairs000066400000000000000000000000221467060157400170450ustar00rootroot00000000000000A B C D E F bcftools-1.21/test/gtcheck.4.vcf000066400000000000000000000015421467060157400165150ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D E F 1 1 . C T . PASS . GT 0/0 0/0 0/0 0/0 0/0 1/1 1 2 . C T . PASS . GT 0/0 0/0 0/0 1/1 0/0 1/1 1 3 . C T . PASS . GT 0/0 1/1 0/0 1/1 0/0 1/1 2 1 . C T . PASS . GT 0/0 0/0 0/0 0/0 0/0 1/1 2 2 . C T . PASS . GT 0/0 0/0 0/0 1/1 0/0 1/1 2 3 . C T . PASS . GT 0/0 1/1 0/0 1/1 0/0 1/1 3 1 . C T . PASS . GT 0/0 0/0 0/0 0/0 0/0 1/1 3 2 . C T . PASS . GT 0/0 0/0 0/0 1/1 0/0 1/1 3 3 . C T . PASS . GT 0/0 1/1 0/0 1/1 0/0 1/1 bcftools-1.21/test/gtcheck.5.1.out000066400000000000000000000006311467060157400167040ustar00rootroot00000000000000INFO sites-compared 2 INFO sites-skipped-no-match 3 INFO sites-skipped-multiallelic 1 INFO sites-skipped-monoallelic 1 INFO sites-skipped-no-data 1 INFO sites-skipped-GT-not-diploid 1 INFO sites-skipped-PL-not-diploid 1 INFO sites-skipped-filtering-expression 0 INFO sites-used-PL-vs-PL 0 INFO sites-used-PL-vs-GT 1 INFO sites-used-GT-vs-PL 0 INFO sites-used-GT-vs-GT 1 DCv2 A A 1.000089e-12 0.000000e+00 2 2 bcftools-1.21/test/gtcheck.5.gts.vcf000066400000000000000000000010211467060157400173020ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fa ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3775163 . T A . . . GT 1/1 1 3775163 . T C . . . GT 1/1 1 3781099 . T . . . . GT 1/1 1 3781105 . G C . . . GT 0/0 1 3781111 . G C . . . GT 0/0 1 3781602 . A T,C . . . GT 1/1 1 3782656 . A T . . . GT 1/1 1 3782657 . A T . . . GT 1/1 1 3782658 . A T . . . . . bcftools-1.21/test/gtcheck.5.out000066400000000000000000000000341467060157400165420ustar00rootroot00000000000000DCv2 B D 2 0.000000e+00 2 0 bcftools-1.21/test/gtcheck.5.vcf000066400000000000000000000010531467060157400165130ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fa ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3775163 . T . . . GT:PL 0/0:0,81,1800 1 3781099 . T . . . . GT:PL 0/0:0,120,1800 1 3781105 . G C . . . GT 0/0 1 3781111 . G C . . . PL 0,120,1800 1 3781602 . A C,T . . . GT:PL 0/0:0,120,1800 1 3782656 . A T . . . GT 0 1 3782657 . A T . . . PL 0,10 1 3782658 . A T . . . . . bcftools-1.21/test/gtcheck.6.1.out000066400000000000000000000001161467060157400167030ustar00rootroot00000000000000DCv2 A B 0.000000e+00 5.753641e-01 1 1 DCv2 B C 9.210340e+00 0.000000e+00 1 0 bcftools-1.21/test/gtcheck.6.out000066400000000000000000000000701467060157400165430ustar00rootroot00000000000000DCv2 B C 1 8.675006e-01 2 1 DCv2 B D 2 0.000000e+00 2 0 bcftools-1.21/test/gtcheck.6.vcf000066400000000000000000000003571467060157400165220ustar00rootroot00000000000000##fileformat=VCFv4.3 ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 1 . C T . PASS . GT 0/0 0/0 0/1 0/1 bcftools-1.21/test/gtcheck.7.out000066400000000000000000000000361467060157400165460ustar00rootroot00000000000000DCv2 s1 s1 0 0.000000e+00 1 1 bcftools-1.21/test/gtcheck.8.out000066400000000000000000000002001467060157400165400ustar00rootroot00000000000000DCv2 A B 3 5.877867e-01 9 6 DCv2 C D 6 3.646431e-01 9 3 DCv2 E F 9 0.000000e+00 9 0 DS 1 3 3 0 DS 2 3 3 1 DS 3 3 3 2 DS 3 2 2 3 bcftools-1.21/test/gtcheck.9.out000066400000000000000000000004301467060157400165460ustar00rootroot00000000000000DCv2 B A 0 1.126897e+00 2 2 DCv2 C A 1 8.675006e-01 2 1 DCv2 C B 1 8.675006e-01 2 1 DCv2 D A 2 0.000000e+00 2 0 DCv2 D B 2 0.000000e+00 2 0 DCv2 D C 2 0.000000e+00 2 0 DCv2 E A 2 0.000000e+00 2 0 DCv2 E B 2 0.000000e+00 2 0 DCv2 E C 1 1.386294e+00 2 1 DCv2 E D 1 7.133499e-01 2 1 bcftools-1.21/test/gtcheck.ntop.1.out000066400000000000000000000004021467060157400175140ustar00rootroot00000000000000DCv2 smpl x1 9.210340e+01 8.109302e-01 6 1 DCv2 smpl x2 1.842068e+01 9.518185e-01 6 5 DCv2 smpl x3 0.000000e+00 9.518185e-01 5 5 DCv2 smpl x4 5.526204e+01 7.324082e-01 6 3 DCv2 smpl x5 0.000000e+00 9.634573e-01 6 6 DCv2 smpl x6 7.368272e+01 6.931472e-01 6 2 bcftools-1.21/test/gtcheck.ntop.2.out000066400000000000000000000001261467060157400175200ustar00rootroot00000000000000DCv2 smpl x3 0.000000e+00 9.518185e-01 5 5 DCv2 smpl x5 0.000000e+00 9.634573e-01 6 6 bcftools-1.21/test/gtcheck.ntop.gts.vcf000066400000000000000000000007331467060157400201270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT x1 x2 x3 x4 x5 x6 1 10 . C A . . . GT 0/0 0/0 ./. 1/1 1/1 1/1 1 11 . C A . . . GT 0/0 1/1 1/1 1/1 1/1 1/1 1 12 . C A . . . GT 0/0 1/1 1/1 1/1 1/1 0/0 1 13 . C A . . . GT 0/0 1/1 1/1 0/0 1/1 0/0 1 14 . C A . . . GT 0/0 1/1 1/1 0/0 1/1 0/0 1 15 . C A . . . GT 1/1 1/1 1/1 0/0 1/1 0/0 bcftools-1.21/test/gtcheck.ntop.vcf000066400000000000000000000005261467060157400173330ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl 1 10 . C A . . . GT 1/1 1 11 . C A . . . GT 1/1 1 12 . C A . . . GT 1/1 1 13 . C A . . . GT 1/1 1 14 . C A . . . GT 1/1 1 15 . C A . . . GT 1/1 bcftools-1.21/test/guess-ploidy.GL.out000066400000000000000000000004061467060157400177170ustar00rootroot00000000000000# [1]SEX [2]Sample [3]Predicted sex [4]log P(Haploid)/nSites [5]log P(Diploid)/nSites [6]nSites [7]Score: F < 0 < M ($4-$5) SEX NA00001 M -0.592820 -1.185639 4 0.592819 SEX NA00002 M -0.318166 -0.636333 4 0.318166 SEX NA00003 F -14.297587 -0.750505 3 -13.547082 bcftools-1.21/test/guess-ploidy.PL.out000066400000000000000000000004061467060157400177300ustar00rootroot00000000000000# [1]SEX [2]Sample [3]Predicted sex [4]log P(Haploid)/nSites [5]log P(Diploid)/nSites [6]nSites [7]Score: F < 0 < M ($4-$5) SEX NA00001 M -0.592820 -1.185639 4 0.592819 SEX NA00002 M -0.318166 -0.636333 4 0.318166 SEX NA00003 F -14.297587 -0.750505 3 -13.547082 bcftools-1.21/test/gvcf.fa000066400000000000000000000007301467060157400154760ustar00rootroot00000000000000>22 NNNNNNNNCCTTGGCCAAGTCACTTCCTCCTTCAGGAACATTGCAGTGGGCCTAAGTGCC TCCTCTCGGGACTGGTATGGGGACGGTCATGCAATCTGGACAACATTCACCTTTAAAAGT TTATTGATCTTTTGTGACATGCACGTGGGTTCCCAGTAGCAAGAAACTAAAGGGTCGCAG GCCGGTTTCTGCTAATTTCTTTAATTCCAAGACAGTCTCAAATATTTTCTTATTAACTTC CTGGAGGGAGGCTTATCATTCTCTCTTTTGGATGATTCTAAGTACCAGCTAAAATACAGC TATCATTCATTTTCCTTGATTTGGGAGCCTAATTTCTTTAATTTAGTATGCAAGAAAACC AATTTGGAAATATCAACTGTTTTGGAAACCTTAGACCTAGGTCATCCTTAGTAAGATCTT CCCATTTATATAAATACTTGCAAGTAGTAGTGCCATAATT bcftools-1.21/test/gvcf.merge.1.out000066400000000000000000000052761467060157400171660ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FILTER= ##FILTER= ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT G06 D05 H09 chr1 10106 . C . 0 LowGQX BLOCKAVG_min30p3a;AN=2 GT:GQX:DP:DPF ./.:.:.:. 0/0:12:5:0 ./.:.:.:. chr1 10107 . C . 0 LowGQX;HighDPFRatio BLOCKAVG_min30p3a;AN=4 GT:GQX:DP:DPF .:.:0:1 0/0:12:5:0 0/0:5:2:0 chr1 10108 . N . 0 LowGQX;HighDPFRatio END=10110;BLOCKAVG_min30p3a;AN=2 GT:GQX:DP:DPF .:.:0:1 ./.:.:.:. 0/0:5:2:0 chr1 10111 . N . 0 LowGQX END=10120;BLOCKAVG_min30p3a;AN=2 GT:GQX:DP:DPF ./.:.:.:. ./.:.:.:. 0/0:5:2:0 bcftools-1.21/test/gvcf.merge.1.vcf000066400000000000000000000045621467060157400171320ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT G06 chr1 10107 . C . 0.00 LowGQX;HighDPFRatio END=10110;BLOCKAVG_min30p3a GT:GQX:DP:DPF .:.:0:1 bcftools-1.21/test/gvcf.merge.2.vcf000066400000000000000000000045501467060157400171300ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT D05 chr1 10106 . C . 0.00 LowGQX END=10107;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:12:5:0 bcftools-1.21/test/gvcf.merge.3.vcf000066400000000000000000000045471467060157400171370ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT H09 chr1 10107 . C . 0.00 LowGQX END=10120;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:5:2:0 bcftools-1.21/test/gvcfz.1.out000066400000000000000000000002741467060157400162530ustar00rootroot0000000000000010001 T . 10145 ./. 6 . 0 10146 A . 10146 1/1 19 33 . 10147 C . 10173 ./. 18 . 0 10174 C . 10174 0/1 20 10 . 10175 T . 10246 ./. 14 . 0 10247 T . 10247 1/1 2 6 . 10248 A . 12595 ./. 0 . . bcftools-1.21/test/gvcfz.2.1.out000066400000000000000000000002541467060157400164110ustar00rootroot0000000000000010001 T . . 10145 ./. 6 10146 A . . 10146 1/1 19 10147 C . . 10173 ./. 18 10174 C . . 10174 0/1 20 10175 T . . 10246 ./. 14 10247 T . . 10247 1/1 2 10248 A . . 12595 ./. 0 bcftools-1.21/test/gvcfz.2.out000066400000000000000000000013601467060157400162510ustar00rootroot0000000000000010001 T . FLT 10144 ./. 6 . 0 10145 A . . 10146 0/0 19 15 . 10147 C . FLT 10403 ./. 2 . . 10404 C . . 10404 0/0 27 30 . 10405 C . FLT 10408 0/0 27 . 0 10409 A . . 10409 0/0 27 30 . 10410 C . FLT 10426 0/0 27 . 0 10427 A . . 10427 0/0 26 18 . 10428 C . FLT 10435 0/0 26 . 0 10436 C . . 10436 0/0 26 18 . 10437 T . FLT 10449 ./. 1 . . 10450 T . . 10450 0/0 21 18 . 10451 A . FLT 10456 0/0 18 4 . 10457 A . . 10457 0/0 18 18 . 10458 A . FLT 10466 0/0 9 . 0 10467 C . . 10467 0/0 9 18 . 10468 T . FLT 10472 0/0 7 0 . 10473 G . . 10473 0/0 6 18 . 10474 T . FLT 10474 0/0 6 . 18 10475 A . . 10475 0/0 6 18 . 10476 C . FLT 10491 0/0 6 . 17 10492 C . . 10492 0/0 6 18 . 10493 C . FLT 10503 0/0 6 . 12 10504 G . . 10504 0/0 6 12 . 10505 A . FLT 12595 0/0 0 . . bcftools-1.21/test/gvcfz.2.vcf000066400000000000000000005004771467060157400162350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##reference=file:GRCh38_full_analysis_set_plus_decoy_hla.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HGDP01406 chr1 10001 . T . . . AN=142;DP=1225 GT:AD:DP ./.:9:10 chr1 10002 . A . . . AN=210;DP=1484 GT:AD:DP ./.:9:10 chr1 10003 . A . . . AN=282;DP=1841 GT:AD:DP ./.:5:6 chr1 10004 . C . . . AN=372;DP=3134 GT:AD:DP 0/0:10:10 chr1 10005 . C . . . AN=418;DP=4796 GT:AD:DP 0/0:10:10 chr1 10006 . C . . . AN=452;DP=6739 GT:AD:DP ./.:9:10 chr1 10007 . T . . . AN=448;DP=7774 GT:AD:DP ./.:7:8 chr1 10008 . A . . . AN=484;DP=8907 GT:AD:DP 0/0:8:8 chr1 10009 . A . . . AN=472;DP=9764 GT:AD:DP ./.:7:10 chr1 10010 . C . . . AN=628;DP=10778 GT:AD:DP 0/0:10:10 chr1 10011 . C . . . AN=654;DP=11507 GT:AD:DP 0/0:10:10 chr1 10012 . C . . . AN=642;DP=12220 GT:AD:DP 0/0:10:10 chr1 10013 . T . . . AN=610;DP=12731 GT:AD:DP 0/0:10:10 chr1 10014 . A . . . AN=660;DP=13276 GT:AD:DP 0/0:10:10 chr1 10015 . A . . . AN=638;DP=13515 GT:AD:DP 0/0:6:6 chr1 10016 . C . . . AN=842;DP=14415 GT:AD:DP 0/0:11:11 chr1 10017 . C . . . AN=892;DP=14946 GT:AD:DP 0/0:11:11 chr1 10018 . C . . . AN=890;DP=15476 GT:AD:DP 0/0:13:13 chr1 10019 . T . . . AN=850;DP=15757 GT:AD:DP 0/0:13:13 chr1 10020 . A C . . AC=0;AF=0;AN=876;BaseQRankSum=-1.026;ClippingRankSum=-1.026;DP=16219;ExcessHet=3.01;MQ=0.64;MQRankSum=-1.026;ReadPosRankSum=0 GT:AD:DP 0/0:14,0:14 chr1 10021 . A . . . AN=862;DP=16482 GT:AD:DP 0/0:12:12 chr1 10022 . C . . . AN=1080;DP=17445 GT:AD:DP 0/0:16:16 chr1 10023 . C A . . AC=0;AF=0;AN=1108;BaseQRankSum=0;ClippingRankSum=-1.026;DP=17982;ExcessHet=3.01;MQ=0.42;MQRankSum=-1.026;ReadPosRankSum=-1.026 GT:AD:DP 0/0:17,0:17 chr1 10024 . C . . . AN=1092;DP=18489 GT:AD:DP 0/0:17:17 chr1 10025 . T . . . AN=1006;DP=18703 GT:AD:DP 0/0:15:17 chr1 10026 . A . . . AN=1042;DP=19207 GT:AD:DP ./.:11:13 chr1 10027 . A . . . AN=964;DP=19358 GT:AD:DP ./.:12:14 chr1 10028 . C . . . AN=1252;DP=20434 GT:AD:DP 0/0:17:18 chr1 10029 . C . . . AN=1314;DP=20989 GT:AD:DP 0/0:19:19 chr1 10030 . C . . . AN=1262;DP=21509 GT:AD:DP 0/0:19:19 chr1 10031 . T . . . AN=1094;DP=21589 GT:AD:DP 0/0:16:17 chr1 10032 . A . . . AN=1150;DP=22097 GT:AD:DP 0/0:16:17 chr1 10033 . A . . . AN=1018;DP=22181 GT:AD:DP 0/0:13:13 chr1 10034 . C . . . AN=1352;DP=23420 GT:AD:DP 0/0:19:19 chr1 10035 . C . . . AN=1430;DP=24000 GT:AD:DP 0/0:19:19 chr1 10036 . C . . . AN=1384;DP=24433 GT:AD:DP 0/0:18:19 chr1 10037 . T C . . AC=0;AF=0;AN=1196;BaseQRankSum=-1.067;ClippingRankSum=-0.572;DP=24414;ExcessHet=3.01;MQ=0.7;MQRankSum=1.59;ReadPosRankSum=-1.589 GT:AD:DP ./.:12,3:15 chr1 10038 . A . . . AN=1234;DP=24915 GT:AD:DP ./.:16:19 chr1 10039 . A . . . AN=1126;DP=24871 GT:AD:DP ./.:11:13 chr1 10040 . C . . . AN=1458;DP=26306 GT:AD:DP 0/0:19:19 chr1 10041 . C . . . AN=1546;DP=26876 GT:AD:DP 0/0:20:20 chr1 10042 . C T . . AC=0;AF=0;AN=1450;BaseQRankSum=-0.572;ClippingRankSum=0.572;DP=27202;ExcessHet=3.01;MQ=0.62;MQRankSum=1.59;ReadPosRankSum=-1.589 GT:AD:DP ./.:17,3:20 chr1 10043 . T . . . AN=1234;DP=27403 GT:AD:DP 0/0:22:24 chr1 10044 . A . . . AN=1340;DP=28147 GT:AD:DP 0/0:20:22 chr1 10045 . A . . . AN=1214;DP=28029 GT:AD:DP 0/0:20:20 chr1 10046 . C . . . AN=1594;DP=30003 GT:AD:DP 0/0:24:24 chr1 10047 . C . . . AN=1698;DP=30908 GT:AD:DP 0/0:24:24 chr1 10048 . C . . . AN=1618;DP=31592 GT:AD:DP 0/0:23:24 chr1 10049 . T C . . AC=0;AF=0;AN=1312;BaseQRankSum=-0.691;ClippingRankSum=-0.296;DP=31423;ExcessHet=3.01;MQ=0.76;MQRankSum=0.731;ReadPosRankSum=0.731 GT:AD:DP ./.:20,2:22 chr1 10050 . A . . . AN=1398;DP=32308 GT:AD:DP 0/0:22:24 chr1 10051 . A . . . AN=1204;DP=32137 GT:AD:DP 0/0:18:19 chr1 10052 . C . . . AN=1624;DP=34288 GT:AD:DP 0/0:23:23 chr1 10053 . C . . . AN=1754;DP=35154 GT:AD:DP 0/0:24:24 chr1 10054 . C A . . AC=0;AF=0;AN=1634;BaseQRankSum=-1.768;ClippingRankSum=-0.354;DP=35626;ExcessHet=3.01;MQ=0.7;MQRankSum=-0.354;ReadPosRankSum=1.06 GT:AD:DP 0/0:23,1:24 chr1 10055 . T C . . AC=0;AF=0;AN=1238;BaseQRankSum=-0.085;ClippingRankSum=-0.217;DP=35165;ExcessHet=3.01;MQ=0.94;MQRankSum=0.505;ReadPosRankSum=-0.934 GT:AD:DP:PGT:PID ./.:19,3:22:.:. chr1 10056 . A T . . AC=0;AF=0;AN=1422;BaseQRankSum=-1.953;ClippingRankSum=-0.085;DP=36206;ExcessHet=3.01;MQ=0.68;MQRankSum=-0.255;ReadPosRankSum=-1.274 GT:AD:DP ./.:21,3:24 chr1 10057 . A G,C . . AC=0,0;AF=0,0;AN=1306;BaseQRankSum=1.23;ClippingRankSum=0.406;DP=35576;ExcessHet=3.01;MQ=0.82;MQRankSum=0.358;ReadPosRankSum=0.762 GT:AD:DP 0/0:19,2,2:21 chr1 10058 . C . . . AN=1688;DP=38186 GT:AD:DP 0/0:22:23 chr1 10059 . C . . . AN=1840;DP=39201 GT:AD:DP 0/0:25:25 chr1 10060 . C G . . AC=0;AF=0;AN=1728;BaseQRankSum=-1.626;ClippingRankSum=-0.287;DP=39538;ExcessHet=3.01;MQ=0.8;MQRankSum=0.957;ReadPosRankSum=2.3 GT:AD:DP 0/0:24,2:26 chr1 10061 . T C . . AC=0;AF=0;AN=1480;BaseQRankSum=-1.055;ClippingRankSum=0.754;DP=38726;ExcessHet=3.01;MQ=0.74;MQRankSum=1.66;ReadPosRankSum=-1.759 GT:AD:DP ./.:20,6:26 chr1 10062 . A . . . AN=1666;DP=39902 GT:AD:DP ./.:22:25 chr1 10063 . A . . . AN=1468;DP=38892 GT:AD:DP ./.:19:22 chr1 10064 . C A . . AC=0;AF=0;AN=1780;BaseQRankSum=-1.191;ClippingRankSum=-0.764;DP=41451;ExcessHet=3.01;MQ=0.75;MQRankSum=-0.714;ReadPosRankSum=0.085 GT:AD:DP ./.:22,2:24 chr1 10065 . C . . . AN=1866;DP=42364 GT:AD:DP 0/0:29:30 chr1 10066 . C . . . AN=1800;DP=42517 GT:AD:DP 0/0:29:30 chr1 10067 . T . . . AN=1618;DP=41473 GT:AD:DP 0/0:24:26 chr1 10068 . A . . . AN=1696;DP=42685 GT:AD:DP 0/0:29:30 chr1 10069 . A . . . AN=1636;DP=41463 GT:AD:DP 0/0:28:30 chr1 10070 . C . . . AN=1862;DP=44361 GT:AD:DP 0/0:30:33 chr1 10071 . C . . . AN=1892;DP=45033 GT:AD:DP 0/0:34:34 chr1 10072 . C . . . AN=1852;DP=44940 GT:AD:DP 0/0:31:31 chr1 10073 . T . . . AN=1694;DP=43326 GT:AD:DP 0/0:30:31 chr1 10074 . A . . . AN=1800;DP=44368 GT:AD:DP 0/0:31:32 chr1 10075 . A . . . AN=1766;DP=42682 GT:AD:DP 0/0:28:28 chr1 10076 . C . . . AN=1882;DP=45295 GT:AD:DP 0/0:31:32 chr1 10077 . C . . . AN=1890;DP=45723 GT:AD:DP 0/0:34:34 chr1 10078 . C . . . AN=1878;DP=45370 GT:AD:DP 0/0:32:32 chr1 10079 . T . . . AN=1746;DP=43529 GT:AD:DP 0/0:29:30 chr1 10080 . A . . . AN=1816;DP=44625 GT:AD:DP 0/0:31:34 chr1 10081 . A . . . AN=1822;DP=42816 GT:AD:DP 0/0:28:28 chr1 10082 . C . . . AN=1890;DP=45409 GT:AD:DP 0/0:32:32 chr1 10083 . C . . . AN=1908;DP=45761 GT:AD:DP 0/0:35:35 chr1 10084 . C G . . AC=0;AF=0;AN=1896;DP=45157;ExcessHet=3.01;MQ=0.52 GT:AD:DP:PGT:PID 0/0:30,3:33:.:. chr1 10085 . T . . . AN=1740;DP=43001 GT:AD:DP 0/0:32:33 chr1 10086 . A . . . AN=1842;DP=44251 GT:AD:DP 0/0:30:32 chr1 10087 . A . . . AN=1818;DP=42424 GT:AD:DP 0/0:33:33 chr1 10088 . C . . . AN=1878;DP=44829 GT:AD:DP 0/0:33:34 chr1 10089 . C . . . AN=1908;DP=45166 GT:AD:DP 0/0:36:36 chr1 10090 . C . . . AN=1886;DP=44473 GT:AD:DP ./.:31:35 chr1 10091 . T . . . AN=1790;DP=42136 GT:AD:DP ./.:30:35 chr1 10092 . A . . . AN=1870;DP=43367 GT:AD:DP 0/0:33:35 chr1 10093 . A . . . AN=1866;DP=41414 GT:AD:DP ./.:27:30 chr1 10094 . C . . . AN=1898;DP=43793 GT:AD:DP 0/0:33:34 chr1 10095 . C . . . AN=1906;DP=44121 GT:AD:DP 0/0:37:37 chr1 10096 . C . . . AN=1884;DP=43213 GT:AD:DP 0/0:34:35 chr1 10097 . T . . . AN=1746;DP=40716 GT:AD:DP 0/0:32:33 chr1 10098 . A . . . AN=1864;DP=41862 GT:AD:DP 0/0:35:36 chr1 10099 . A . . . AN=1800;DP=39808 GT:AD:DP 0/0:34:34 chr1 10100 . C . . . AN=1890;DP=42197 GT:AD:DP 0/0:35:36 chr1 10101 . C . . . AN=1912;DP=42210 GT:AD:DP 0/0:40:40 chr1 10102 . C . . . AN=1902;DP=41021 GT:AD:DP 0/0:36:36 chr1 10103 . T . . . AN=1764;DP=37934 GT:AD:DP 0/0:32:34 chr1 10104 . A . . . AN=1864;DP=38851 GT:AD:DP 0/0:37:39 chr1 10105 . A . . . AN=1174;DP=36442 GT:AD:DP 0/0:34:36 chr1 10106 . C . . . AN=1376;DP=37958 GT:AD:DP 0/0:34:37 chr1 10107 . C . . . AN=1766;DP=38020 GT:AD:DP 0/0:37:38 chr1 10108 . C . . . AN=824;DP=36234 GT:AD:DP ./.:33:38 chr1 10109 . A . . . AN=606;DP=35112 GT:AD:DP ./.:32:37 chr1 10110 . A . . . AN=1470;DP=35911 GT:AD:DP 0/0:38:38 chr1 10111 . C . . . AN=1464;DP=36153 GT:AD:DP 0/0:36:37 chr1 10112 . C . . . AN=1696;DP=37152 GT:AD:DP 0/0:39:39 chr1 10113 . C . . . AN=1694;DP=36832 GT:AD:DP 0/0:36:38 chr1 10114 . T . . . AN=1296;DP=34281 GT:AD:DP ./.:28:32 chr1 10115 . A . . . AN=1624;DP=36249 GT:AD:DP 0/0:36:37 chr1 10116 . A . . . AN=1706;DP=36573 GT:AD:DP 0/0:35:37 chr1 10117 . C . . . AN=1642;DP=36650 GT:AD:DP 0/0:36:37 chr1 10118 . C . . . AN=1770;DP=37407 GT:AD:DP 0/0:39:39 chr1 10119 . C . . . AN=1744;DP=36842 GT:AD:DP 0/0:37:40 chr1 10120 . T . . . AN=1352;DP=34333 GT:AD:DP 0/0:30:33 chr1 10121 . A . . . AN=1666;DP=35770 GT:AD:DP 0/0:35:36 chr1 10122 . A . . . AN=1760;DP=35740 GT:AD:DP 0/0:37:37 chr1 10123 . C . . . AN=1652;DP=35808 GT:AD:DP 0/0:37:38 chr1 10124 . C . . . AN=1770;DP=36195 GT:AD:DP 0/0:40:40 chr1 10125 . C . . . AN=1758;DP=35476 GT:AD:DP 0/0:38:40 chr1 10126 . T . . . AN=1368;DP=33158 GT:AD:DP 0/0:28:30 chr1 10127 . A . . . AN=1652;DP=34300 GT:AD:DP 0/0:36:37 chr1 10128 . A . . . AN=1652;DP=34091 GT:AD:DP 0/0:35:35 chr1 10129 . C . . . AN=1536;DP=34064 GT:AD:DP 0/0:35:37 chr1 10130 . C . . . AN=1740;DP=34095 GT:AD:DP 0/0:38:39 chr1 10131 . CT C . . AC=0;AF=0;AN=1718;BaseQRankSum=0.898;ClippingRankSum=-0.48;DP=33151;ExcessHet=3.01;MQ=0.61;MQRankSum=1.27;ReadPosRankSum=-0.898 GT:AD:DP 0/0:36,1:37 chr1 10132 . T . . . AN=1262;DP=30953 GT:AD:DP 0/0:33:35 chr1 10133 . A T,C . . AC=0,0;AF=0,0;AN=1618;BaseQRankSum=0.82;ClippingRankSum=-0.224;DP=31600;ExcessHet=3.01;MQ=0.84;MQRankSum=0.358;ReadPosRankSum=2.01 GT:AD:DP:PGT:PID 0/0:36,3,3:39:.:. chr1 10134 . ACCCTAACCCTAAC A,CCCCTAACCCTAAC,GCCCTAACCCTAAC . . AC=0,0,0;AF=0,0,0;AN=1674;BaseQRankSum=0;ClippingRankSum=-0.48;DP=31150;ExcessHet=3.01;MQ=1.11;MQRankSum=1.02;ReadPosRankSum=-1.698 GT:AD:DP:PGT:PID 0/0:35,4,4,4:39:.:. chr1 10135 . CCCTAA C 103.37 . AC=4;AF=0.002077;AN=1926;BaseQRankSum=0;ClippingRankSum=0;DP=30829;ExcessHet=34.1598;FS=0;InbreedingCoeff=-0.0627;MLEAC=4;MLEAF=0.002077;MQ=0.94;MQRankSum=1.03;QD=6.46;ReadPosRankSum=1.73;SOR=0.693 GT:AD:DP:PL 0/0:35,5:40:0,0,897 chr1 10136 . C . . . AN=1710;DP=30738 GT:AD:DP 0/0:38:40 chr1 10137 . C A . . AC=0;AF=0;AN=1658;BaseQRankSum=-0.822;ClippingRankSum=-1.369;DP=29868;ExcessHet=3.01;MQ=0.72;MQRankSum=-0.822;ReadPosRankSum=-1.187 GT:AD:DP 0/0:35,2:37 chr1 10138 . TA T 256.35 . AC=2;AF=0.001037;AN=1928;BaseQRankSum=-1.123;ClippingRankSum=-0.964;DP=27643;ExcessHet=121.32;FS=1.909;InbreedingCoeff=-0.1243;MLEAC=1;MLEAF=0.0005187;MQ=1.62;MQRankSum=-0.102;QD=34.24;ReadPosRankSum=-0.964;SOR=0.346 GT:AD:DP:PGT:PID:PL 0/0:27,6:33:.:.:0,0,634 chr1 10139 . A G,C . . AC=0,0;AF=0,0;AN=1506;BaseQRankSum=0.351;ClippingRankSum=-0.299;DP=28276;ExcessHet=3.01;MQ=1.19;MQRankSum=1.19;ReadPosRankSum=0.179 GT:AD:DP 0/0:34,3,3:37 chr1 10140 . A AC,C . . AC=0,0;AF=0,0;AN=1534;BaseQRankSum=-0.572;ClippingRankSum=0;DP=27747;ExcessHet=3.01;MQ=0.61;MQRankSum=1.07;ReadPosRankSum=1.59 GT:AD:DP:PGT:PID 0/0:35,2,2:37:.:. chr1 10141 . C . . . AN=1344;DP=27401 GT:AD:DP ./.:33:38 chr1 10142 . C . . . AN=1650;DP=27116 GT:AD:DP 0/0:36:39 chr1 10143 . CTAACCCCT C . . AC=0;AF=0;AN=1558;DP=26067;ExcessHet=3.01;MQ=0.41 GT:AD:DP 0/0:35,0:35 chr1 10144 . T C 815.07 . AC=3;AF=0.001567;AN=1914;BaseQRankSum=-0.942;ClippingRankSum=0.322;DP=23831;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.183;MLEAC=3;MLEAF=0.001567;MQ=1.52;MQRankSum=0.898;QD=21.45;ReadPosRankSum=0.322;SOR=0.544 GT:AD:DP:PGT:PID:PL 0/0:25,7:32:.:.:0,0,563 chr1 10145 . AAC A 151.43 . AC=4;AF=0.002083;AN=1920;BaseQRankSum=0.72;ClippingRankSum=0;DP=24144;ExcessHet=160.275;FS=0;InbreedingCoeff=-0.1558;MLEAC=5;MLEAF=0.002604;MQ=1.63;MQRankSum=0.764;QD=3.52;ReadPosRankSum=0.085;SOR=0.458 GT:AD:DP:PL 0/0:31,2:33:0,15,225 chr1 10146 . AC A 26025.4 . AC=214;AF=0.112;AN=1914;BaseQRankSum=-0.532;ClippingRankSum=-0.398;DP=21832;ExcessHet=19.5226;FS=0.819;InbreedingCoeff=0.0115;MLEAC=217;MLEAF=0.113;MQ=9.12;MQRankSum=0.358;QD=16.05;ReadPosRankSum=0.736;SOR=0.841 GT:AD:DP:PGT:PID:PL 1/1:0,19:19:1|1:10146_AC_A:209,33,0 chr1 10147 . CCCCT C,ACCCT . . AC=0,0;AF=0,0;AN=280;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=23027;ExcessHet=3.01;MQ=0.73;MQRankSum=0.727;ReadPosRankSum=0.727 GT:AD:DP ./.:22,9,9:31 chr1 10148 . C CCTAA . . AC=0;AF=0;AN=416;BaseQRankSum=-1.026;ClippingRankSum=0;DP=23009;ExcessHet=3.01;MQ=0.62;MQRankSum=1.03;ReadPosRankSum=0 GT:AD:DP:PGT:PID ./.:23,7:30:.:. chr1 10149 . CCT C . . AC=0;AF=0;AN=1304;BaseQRankSum=0.736;ClippingRankSum=1.27;DP=22319;ExcessHet=3.01;MQ=1.02;MQRankSum=0.736;ReadPosRankSum=0.736 GT:AD:DP:PGT:PID ./.:25,5:30:.:. chr1 10150 . CT C 1490.44 . AC=2;AF=0.001073;AN=1864;BaseQRankSum=-0.922;ClippingRankSum=-0.47;DP=21029;ExcessHet=2.14748e+09;FS=3.027;InbreedingCoeff=-0.2397;MLEAC=2;MLEAF=0.001073;MQ=1.54;MQRankSum=0.198;QD=30.63;ReadPosRankSum=0.118;SOR=0.326 GT:AD:DP:PGT:PID:PL 0/0:21,6:27:.:.:0,0,556 chr1 10151 . T A 3248.37 . AC=3;AF=0.001604;AN=1870;BaseQRankSum=-0.922;ClippingRankSum=-0.742;DP=19977;ExcessHet=2.14748e+09;FS=1.524;InbreedingCoeff=-0.2556;MLEAC=2;MLEAF=0.00107;MQ=1.59;MQRankSum=0.742;QD=29.09;ReadPosRankSum=0;SOR=0.404 GT:AD:DP:PGT:PID:PL 0/0:19,4:23:.:.:0,0,495 chr1 10152 . A T 39.55 . AC=2;AF=0.001078;AN=1856;DP=20329;ExcessHet=114.931;FS=0;InbreedingCoeff=-0.1535;MLEAC=2;MLEAF=0.001078;MQ=0.21;QD=19.77;SOR=0.693 GT:AD:DP:PGT:PID:PL 0/0:22,1:23:.:.:0,3,45 chr1 10153 . A G 230.28 . AC=1;AF=0.0005365;AN=1864;BaseQRankSum=1.03;ClippingRankSum=0;DP=20132;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.1988;MLEAC=1;MLEAF=0.0005365;MQ=0.55;MQRankSum=0.736;QD=32.93;ReadPosRankSum=1.03;SOR=0.892 GT:AD:DP:PGT:PID:PL 0/0:21,3:24:.:.:0,0,608 chr1 10154 . C . . . AN=1270;DP=20527 GT:AD:DP ./.:19:24 chr1 10155 . C . . . AN=1498;DP=20430 GT:AD:DP 0/0:18:20 chr1 10156 . CTAACCCTAACCCTAACCCTAACCT C 98.63 . AC=1;AF=0.0005359;AN=1866;BaseQRankSum=0.762;ClippingRankSum=-1.179;DP=20015;ExcessHet=77.564;FS=0;InbreedingCoeff=-0.1213;MLEAC=1;MLEAF=0.0005359;MQ=0.79;MQRankSum=1.67;QD=10.96;ReadPosRankSum=1.59;SOR=0.941 GT:AD:DP:PGT:PID:PL 0/0:19,1:20:.:.:0,6,90 chr1 10157 . T C 62.24 . AC=2;AF=0.001064;AN=1880;BaseQRankSum=0.747;ClippingRankSum=0.747;DP=19277;ExcessHet=2.14748e+09;FS=2.197;InbreedingCoeff=-0.1738;MLEAC=2;MLEAF=0.001064;MQ=0.78;MQRankSum=0.747;QD=6.92;ReadPosRankSum=0.747;SOR=1.402 GT:AD:DP:PGT:PID:PL 0/0:15,4:19:.:.:0,0,393 chr1 10158 . A . . . AN=1278;DP=19621 GT:AD:DP 0/0:17:18 chr1 10159 . A G,C . . AC=0,0;AF=0,0;AN=1176;BaseQRankSum=-0.72;ClippingRankSum=0.742;DP=19356;ExcessHet=3.01;MQ=0.72;MQRankSum=0.742;ReadPosRankSum=1.38 GT:AD:DP:PGT:PID 0/0:17,1,1:18:.:. chr1 10160 . C . . . AN=1364;DP=19667 GT:AD:DP ./.:19:20 chr1 10161 . C . . . AN=1516;DP=19658 GT:AD:DP ./.:20:21 chr1 10162 . C . . . AN=1368;DP=19309 GT:AD:DP ./.:19:20 chr1 10163 . T C 61.11 . AC=1;AF=0.0005285;AN=1892;BaseQRankSum=-0.956;ClippingRankSum=0.322;DP=18670;ExcessHet=166.599;FS=0;InbreedingCoeff=-0.1679;MLEAC=2;MLEAF=0.001057;MQ=0.51;MQRankSum=-0.684;QD=7.64;ReadPosRankSum=-1.221;SOR=1.034 GT:AD:DP:PGT:PID:PL 0/0:17,4:21:.:.:0,0,490 chr1 10164 . A T 37.93 . AC=2;AF=0.001076;AN=1858;DP=18924;ExcessHet=68.3389;FS=0;InbreedingCoeff=-0.1175;MLEAC=1;MLEAF=0.0005382;MQ=0.22;QD=18.96;SOR=0.693 GT:AD:DP:PGT:PID:PL 0/0:21,1:22:.:.:0,6,90 chr1 10165 . A C,G . . AC=0,0;AF=0,0;AN=1134;BaseQRankSum=0.736;ClippingRankSum=0;DP=18656;ExcessHet=3.01;MQ=0.81;MQRankSum=0;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID ./.:19,5,5:24:.:. chr1 10166 . C . . . AN=1372;DP=18881 GT:AD:DP ./.:19:24 chr1 10167 . C . . . AN=1354;DP=18848 GT:AD:DP 0/0:20:22 chr1 10168 . CTAACCCTAACCT C . . AC=0;AF=0;AN=1198;BaseQRankSum=1.22;ClippingRankSum=0.322;DP=18552;ExcessHet=3.01;MQ=0.97;MQRankSum=0.322;ReadPosRankSum=3.14 GT:AD:DP:PGT:PID ./.:18,2:20:.:. chr1 10169 . T . . . AN=776;DP=17980 GT:AD:DP ./.:13:18 chr1 10170 . AACCCT A . . AC=0;AF=0;AN=1064;DP=18138;ExcessHet=3.01;MQ=0.44 GT:AD:DP:PGT:PID ./.:19,3:22:.:. chr1 10171 . A G,C . . AC=0,0;AF=0,0;AN=800;BaseQRankSum=0.572;ClippingRankSum=-1.026;DP=17854;ExcessHet=3.01;MQ=0.78;MQRankSum=0.736;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID ./.:19,3,3:22:.:. chr1 10172 . CCCTAA C . . AC=0;AF=0;AN=582;DP=18024;ExcessHet=3.01;MQ=0.31 GT:AD:DP 0/0:18,2:20 chr1 10173 . C . . . AN=462;DP=18018 GT:AD:DP ./.:19:22 chr1 10174 . CTAACCT C 130.07 . AC=2;AF=0.001112;AN=1798;BaseQRankSum=0.762;ClippingRankSum=-0.067;DP=17745;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2796;MLEAC=8;MLEAF=0.004449;MQ=1.28;MQRankSum=2.21;QD=4.49;ReadPosRankSum=2.21;SOR=1.136 GT:AD:DP:PGT:PID:PL 0/1:2,18:20:0|1:10146_AC_A:171,0,10 chr1 10175 . T . . . AN=76;DP=17217 GT:AD:DP ./.:12:17 chr1 10176 . A . . . AN=154;DP=17453 GT:AD:DP ./.:12:16 chr1 10177 . A C 105.77 . AC=3;AF=0.002538;AN=1182;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=17331;ExcessHet=138.359;FS=0;InbreedingCoeff=-0.2972;MLEAC=39;MLEAF=0.033;MQ=0.71;MQRankSum=0.727;QD=26.44;ReadPosRankSum=-0.727;SOR=1.447 GT:AD:DP:PGT:PID:PL 0/0:10,8:18:.:.:0,0,21 chr1 10178 . C . . . AN=2;DP=17814 GT:AD:DP ./.:9:17 chr1 10179 . C . . . AN=48;DP=17939 GT:AD:DP ./.:12:15 chr1 10180 . T C 2135.86 . AC=1;AF=0.001057;AN=946;BaseQRankSum=0.779;ClippingRankSum=0.779;DP=17651;ExcessHet=157.048;FS=4.481;InbreedingCoeff=-0.295;MLEAC=2;MLEAF=0.002114;MQ=0.82;MQRankSum=1.07;QD=30.83;ReadPosRankSum=1.59;SOR=0.148 GT:AD:DP:PGT:PID:PL 0/0:9,5:14:.:.:0,0,49 chr1 10181 . A . . . AN=56;DP=17926 GT:AD:DP ./.:14:18 chr1 10182 . A . . . AN=168;DP=18128 GT:AD:DP ./.:15:18 chr1 10183 . C . . . AN=204;DP=18717 GT:AD:DP ./.:13:17 chr1 10184 . C . . . AN=292;DP=19115 GT:AD:DP ./.:16:19 chr1 10185 . C . . . AN=304;DP=19250 GT:AD:DP ./.:15:17 chr1 10186 . T . . . AN=190;DP=18962 GT:AD:DP ./.:10:14 chr1 10187 . A . . . AN=252;DP=19379 GT:AD:DP ./.:13:17 chr1 10188 . A . . . AN=238;DP=19503 GT:AD:DP ./.:16:19 chr1 10189 . C . . . AN=326;DP=20077 GT:AD:DP ./.:13:16 chr1 10190 . C . . . AN=368;DP=20381 GT:AD:DP ./.:16:19 chr1 10191 . C . . . AN=332;DP=20429 GT:AD:DP ./.:17:19 chr1 10192 . T . . . AN=240;DP=20079 GT:AD:DP ./.:17:19 chr1 10193 . A . . . AN=286;DP=20350 GT:AD:DP ./.:17:19 chr1 10194 . A . . . AN=274;DP=20335 GT:AD:DP ./.:15:19 chr1 10195 . C A . . AC=0;AF=0;AN=306;DP=20890;ExcessHet=3.01;MQ=0.46 GT:AD:DP:PGT:PID ./.:17,2:19:.:. chr1 10196 . C . . . AN=320;DP=21033 GT:AD:DP ./.:17:19 chr1 10197 . C . . . AN=320;DP=20888 GT:AD:DP ./.:15:19 chr1 10198 . T . . . AN=258;DP=20461 GT:AD:DP ./.:14:19 chr1 10199 . A . . . AN=320;DP=20674 GT:AD:DP ./.:18:21 chr1 10200 . AC A . . AC=0;AF=0;AN=302;BaseQRankSum=-0.358;ClippingRankSum=-1.231;DP=20547;ExcessHet=3.01;MQ=0.79;MQRankSum=1.23;ReadPosRankSum=-0.358 GT:AD:DP ./.:17,2:19 chr1 10201 . C . . . AN=326;DP=21024 GT:AD:DP ./.:18:21 chr1 10202 . C . . . AN=330;DP=21163 GT:AD:DP ./.:15:19 chr1 10203 . C . . . AN=324;DP=21047 GT:AD:DP ./.:14:19 chr1 10204 . T A,C . . AC=0,0;AF=0,0;AN=294;BaseQRankSum=0;ClippingRankSum=-1.067;DP=20554;ExcessHet=3.01;MQ=0.75;MQRankSum=0.572;ReadPosRankSum=1.07 GT:AD:DP:PGT:PID ./.:15,4,4:19:.:. chr1 10205 . AACCCTAACCCTAACCCTAACCCTAACCCCTAACCCT A . . AC=0;AF=0;AN=320;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=20661;ExcessHet=3.01;MQ=0.69;MQRankSum=0.727;ReadPosRankSum=0.727 GT:AD:DP ./.:16,5:21 chr1 10206 . A . . . AN=314;DP=20588 GT:AD:DP ./.:12:17 chr1 10207 . C . . . AN=332;DP=20970 GT:AD:DP ./.:16:19 chr1 10208 . C . . . AN=342;DP=20982 GT:AD:DP ./.:16:19 chr1 10209 . C . . . AN=340;DP=20829 GT:AD:DP ./.:17:20 chr1 10210 . T G,C . . AC=0,0;AF=0,0;AN=292;BaseQRankSum=-0.572;ClippingRankSum=0.572;DP=20340;ExcessHet=3.01;MQ=0.82;MQRankSum=0;ReadPosRankSum=0 GT:AD:DP:PGT:PID ./.:17,3,3:20:.:. chr1 10211 . A . . . AN=324;DP=20524 GT:AD:DP 0/0:18:20 chr1 10212 . A . . . AN=290;DP=20333 GT:AD:DP ./.:16:20 chr1 10213 . C . . . AN=326;DP=20716 GT:AD:DP ./.:16:20 chr1 10214 . C . . . AN=366;DP=20793 GT:AD:DP ./.:17:20 chr1 10215 . C . . . AN=338;DP=20574 GT:AD:DP ./.:17:20 chr1 10216 . T G 31.95 . AC=1;AF=0.000618;AN=1618;BaseQRankSum=-0.572;ClippingRankSum=1.59;DP=19936;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2565;MLEAC=6;MLEAF=0.003708;MQ=0.62;MQRankSum=0.572;QD=3.99;ReadPosRankSum=0;SOR=0.307 GT:AD:DP:PGT:PID:PL 0/0:16,4:20:.:.:0,0,365 chr1 10217 . AACCCTAACCCTAACCCCTAACCCT A . . AC=0;AF=0;AN=276;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=20135;ExcessHet=3.01;MQ=0.53;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP ./.:17,2:19 chr1 10218 . A . . . AN=288;DP=19871 GT:AD:DP ./.:16:19 chr1 10219 . C . . . AN=358;DP=20169 GT:AD:DP ./.:15:17 chr1 10220 . C . . . AN=362;DP=20215 GT:AD:DP 0/0:16:17 chr1 10221 . C . . . AN=354;DP=20047 GT:AD:DP ./.:14:17 chr1 10222 . T . . . AN=186;DP=19466 GT:AD:DP ./.:13:17 chr1 10223 . A . . . AN=208;DP=19690 GT:AD:DP ./.:12:17 chr1 10224 . A . . . AN=262;DP=19466 GT:AD:DP 0/0:15:17 chr1 10225 . C . . . AN=334;DP=19844 GT:AD:DP ./.:14:17 chr1 10226 . C . . . AN=378;DP=19926 GT:AD:DP ./.:14:17 chr1 10227 . C . . . AN=350;DP=19824 GT:AD:DP ./.:15:17 chr1 10228 . T . . . AN=212;DP=19193 GT:AD:DP ./.:10:17 chr1 10229 . A . . . AN=190;DP=19311 GT:AD:DP ./.:12:17 chr1 10230 . A . . . AN=16;DP=19225 GT:AD:DP ./.:9:18 chr1 10231 . CCCCTAACCCTAACCCTAAACCCTAAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCAACCCCAACCCCAACCCCAACCCCAACCCCAACCCTAACCCCTAACCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAA C . . AC=0;AF=0;AN=4;DP=19160;ExcessHet=3.01;MQ=0.69 GT:AD:DP ./.:14,3:17 chr1 10232 . C . . . AN=14;DP=19701 GT:AD:DP ./.:11:17 chr1 10233 . C . . . AN=300;DP=19722 GT:AD:DP ./.:10:16 chr1 10234 . CT C . . AC=0;AF=0;AN=118;DP=19134;ExcessHet=3.01;MQ=1 GT:AD:DP:PGT:PID ./.:10,5:15:.:. chr1 10235 . T A . . AC=0;AF=0;AN=16;DP=18692;ExcessHet=3.01;MQ=0.81 GT:AD:DP ./.:9,6:15 chr1 10236 . AACCCT A 42.02 . AC=2;AF=0.001176;AN=1700;DP=19117;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.3123;MLEAC=30;MLEAF=0.018;MQ=0.83;QD=10.5;SOR=1.609 GT:AD:DP:PL 0/0:12,4:16:0,0,196 chr1 10237 . ACCCT A . . AC=0;AF=0;AN=66;DP=19053;ExcessHet=3.01;MQ=0.83 GT:AD:DP:PGT:PID ./.:8,7:15:.:. chr1 10238 . CCCTAA C . . AC=0;AF=0;AN=52;DP=19514;ExcessHet=3.01;MQ=0.41 GT:AD:DP:PGT:PID ./.:10,5:15:.:. chr1 10239 . C . . . AN=110;DP=19773 GT:AD:DP ./.:10:16 chr1 10240 . C . . . AN=78;DP=19632 GT:AD:DP ./.:9:15 chr1 10241 . T . . . AN=10;DP=18948 GT:AD:DP ./.:7:15 chr1 10242 . A . . . AN=102;DP=19331 GT:AD:DP ./.:10:16 chr1 10243 . A AC . . AC=0;AF=0;AN=370;DP=19286;ExcessHet=3.01;MQ=0.49 GT:AD:DP:PGT:PID ./.:10,4:14:.:. chr1 10244 . C . . . AN=242;DP=19645 GT:AD:DP ./.:9:14 chr1 10245 . CCTAAACCCTA C,CAAACCCTA . . AC=0,0;AF=0,0;AN=414;DP=19870;ExcessHet=3.01;MQ=0.75 GT:AD:DP ./.:10,5,5:15 chr1 10246 . C . . . AN=392;DP=19797 GT:AD:DP ./.:9:14 chr1 10247 . TAAACCCTA T 5861 . AC=6;AF=0.007299;AN=822;DP=19019;ExcessHet=89.9389;FS=0;InbreedingCoeff=-0.2627;MLEAC=4;MLEAF=0.004866;MQ=1.81;QD=29.67;SOR=0.735 GT:AD:DP:PGT:PID:PL 1/1:0,2:2:.:.:90,6,0 chr1 10248 . A T 1541.69 . AC=2;AF=0.001427;AN=1402;DP=19322;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.299;MLEAC=1;MLEAF=0.0007133;MQ=0.82;QD=34.04;SOR=0.105 GT:AD:DP:PL ./.:4,11:15:. chr1 10249 . A . . . AN=106;DP=19492 GT:AD:DP ./.:4:16 chr1 10250 . A C 48.14 . AC=5;AF=0.003571;AN=1400;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=19357;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.285;MLEAC=41;MLEAF=0.029;MQ=1.29;MQRankSum=0.804;QD=24.07;ReadPosRankSum=0.804;SOR=1.179 GT:AD:DP:PGT:PID:PL ./.:6,10:16:.:.:. chr1 10251 . C . . . AN=300;DP=19691 GT:AD:DP ./.:6:15 chr1 10252 . C . . . AN=378;DP=20082 GT:AD:DP ./.:6:15 chr1 10253 . C . . . AN=300;DP=19812 GT:AD:DP ./.:8:15 chr1 10254 . T . . . AN=10;DP=19285 GT:AD:DP ./.:5:14 chr1 10255 . A . . . AN=18;DP=19723 GT:AD:DP ./.:6:15 chr1 10256 . A AGATCGG . . AC=0;AF=0;AN=90;DP=19892;ExcessHet=3.01;MQ=0.73 GT:AD:DP ./.:9,8:17 chr1 10257 . A C 179.42 . AC=5;AF=0.003071;AN=1628;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=19756;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2959;MLEAC=47;MLEAF=0.029;MQ=1.24;MQRankSum=0.804;QD=32.42;ReadPosRankSum=0.804;SOR=0.105 GT:AD:DP:PGT:PID:PL 0/0:11,5:16:.:.:0,0,117 chr1 10258 . C . . . AN=580;DP=20650 GT:AD:DP ./.:12:17 chr1 10259 . C . . . AN=632;DP=20735 GT:AD:DP ./.:13:16 chr1 10260 . C . . . AN=634;DP=20380 GT:AD:DP ./.:11:15 chr1 10261 . T . . . AN=164;DP=19444 GT:AD:DP ./.:10:15 chr1 10262 . AACCCT A . . AC=0;AF=0;AN=290;DP=19963;ExcessHet=3.01;MQ=0.45 GT:AD:DP ./.:12,4:16 chr1 10263 . A . . . AN=378;DP=19696 GT:AD:DP ./.:12:16 chr1 10264 . C . . . AN=612;DP=20270 GT:AD:DP ./.:13:16 chr1 10265 . C . . . AN=844;DP=20341 GT:AD:DP ./.:12:17 chr1 10266 . C . . . AN=782;DP=20007 GT:AD:DP ./.:13:17 chr1 10267 . T . . . AN=186;DP=18974 GT:AD:DP ./.:13:16 chr1 10268 . A . . . AN=446;DP=19382 GT:AD:DP ./.:13:17 chr1 10269 . A . . . AN=526;DP=19005 GT:AD:DP ./.:10:17 chr1 10270 . C . . . AN=878;DP=19614 GT:AD:DP ./.:13:17 chr1 10271 . C . . . AN=1054;DP=19601 GT:AD:DP ./.:13:17 chr1 10272 . C . . . AN=1050;DP=19303 GT:AD:DP ./.:14:16 chr1 10273 . T C,G . . AC=0,0;AF=0,0;AN=304;BaseQRankSum=-0.727;ClippingRankSum=-0.727;DP=18171;ExcessHet=3.01;MQ=1.25;MQRankSum=0.727;ReadPosRankSum=0.727 GT:AD:DP:PGT:PID ./.:12,3,3:15:.:. chr1 10274 . A . . . AN=766;DP=18557 GT:AD:DP ./.:12:17 chr1 10275 . A . . . AN=750;DP=18160 GT:AD:DP ./.:12:15 chr1 10276 . C . . . AN=1094;DP=18631 GT:AD:DP ./.:15:17 chr1 10277 . C . . . AN=1284;DP=18578 GT:AD:DP ./.:14:17 chr1 10278 . C . . . AN=1252;DP=18211 GT:AD:DP ./.:14:18 chr1 10279 . T . . . AN=398;DP=16981 GT:AD:DP ./.:11:17 chr1 10280 . A . . . AN=924;DP=17424 GT:AD:DP ./.:15:18 chr1 10281 . A . . . AN=848;DP=17071 GT:AD:DP ./.:12:16 chr1 10282 . CCCTAACCCCAACCCCAACCCCAACCCCAACCCCAACCCCAACCCTAACCCCTAACCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTCGCGGTACCCTCAG C . . AC=0;AF=0;AN=1122;DP=17681;ExcessHet=3.01;MQ=0.75 GT:AD:DP ./.:17,2:19 chr1 10283 . C . . . AN=1360;DP=17755 GT:AD:DP ./.:15:19 chr1 10284 . C . . . AN=1256;DP=17502 GT:AD:DP ./.:13:18 chr1 10285 . T C,G . . AC=0,0;AF=0,0;AN=310;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=16280;ExcessHet=3.01;MQ=1.19;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:PGT:PID ./.:11,4,4:15:.:. chr1 10286 . A . . . AN=706;DP=16747 GT:AD:DP ./.:12:15 chr1 10287 . A . . . AN=728;DP=16239 GT:AD:DP ./.:12:16 chr1 10288 . C . . . AN=980;DP=17164 GT:AD:DP 0/0:16:17 chr1 10289 . C . . . AN=1092;DP=17419 GT:AD:DP ./.:15:17 chr1 10290 . C . . . AN=1068;DP=17300 GT:AD:DP ./.:13:15 chr1 10291 . C T 82.46 . AC=3;AF=0.001765;AN=1700;BaseQRankSum=0.736;ClippingRankSum=0.731;DP=16236;ExcessHet=2.14748e+09;FS=1.778;InbreedingCoeff=-0.2876;MLEAC=20;MLEAF=0.012;MQ=1.79;MQRankSum=0.731;QD=6.87;ReadPosRankSum=-0.731;SOR=0.283 GT:AD:DP:PGT:PID:PL 0/0:11,4:15:.:.:0,0,257 chr1 10292 . A . . . AN=578;DP=16364 GT:AD:DP ./.:13:16 chr1 10293 . A . . . AN=698;DP=15972 GT:AD:DP ./.:10:14 chr1 10294 . C . . . AN=912;DP=17094 GT:AD:DP ./.:13:16 chr1 10295 . C . . . AN=1044;DP=17388 GT:AD:DP ./.:13:16 chr1 10296 . C . . . AN=968;DP=17365 GT:AD:DP ./.:14:19 chr1 10297 . C T 680.86 . AC=3;AF=0.00167;AN=1796;BaseQRankSum=-0.729;ClippingRankSum=0.729;DP=16568;ExcessHet=171.365;FS=8.022;InbreedingCoeff=-0.2456;MLEAC=4;MLEAF=0.002227;MQ=1.92;MQRankSum=0.72;QD=34.04;ReadPosRankSum=0.361;SOR=0.086 GT:AD:DP:PGT:PID:PL 0/0:12,5:17:.:.:0,0,201 chr1 10298 . A . . . AN=556;DP=16437 GT:AD:DP ./.:10:15 chr1 10299 . A . . . AN=640;DP=16131 GT:AD:DP ./.:9:15 chr1 10300 . C . . . AN=880;DP=17272 GT:AD:DP ./.:12:17 chr1 10301 . C . . . AN=1012;DP=17726 GT:AD:DP ./.:15:19 chr1 10302 . C . . . AN=942;DP=17775 GT:AD:DP ./.:14:19 chr1 10303 . C . . . AN=658;DP=17118 GT:AD:DP ./.:13:17 chr1 10304 . A . . . AN=576;DP=16845 GT:AD:DP ./.:13:20 chr1 10305 . A . . . AN=682;DP=16709 GT:AD:DP ./.:13:19 chr1 10306 . C . . . AN=862;DP=17858 GT:AD:DP ./.:11:19 chr1 10307 . C . . . AN=998;DP=18410 GT:AD:DP ./.:17:22 chr1 10308 . C . . . AN=954;DP=18429 GT:AD:DP ./.:17:22 chr1 10309 . C . . . AN=702;DP=17851 GT:AD:DP ./.:14:21 chr1 10310 . A . . . AN=548;DP=17533 GT:AD:DP ./.:14:20 chr1 10311 . A . . . AN=624;DP=17562 GT:AD:DP ./.:14:20 chr1 10312 . C . . . AN=750;DP=18917 GT:AD:DP ./.:16:20 chr1 10313 . C . . . AN=862;DP=19821 GT:AD:DP ./.:18:21 chr1 10314 . C . . . AN=808;DP=20210 GT:AD:DP ./.:16:22 chr1 10315 . C T,A . . AC=0,0;AF=0,0;AN=522;BaseQRankSum=0.358;ClippingRankSum=-0.322;DP=19802;ExcessHet=3.01;MQ=1.43;MQRankSum=0.967;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID ./.:14,7,7:21:.:. chr1 10316 . A . . . AN=346;DP=20040 GT:AD:DP ./.:15:25 chr1 10317 . A . . . AN=386;DP=20533 GT:AD:DP ./.:14:26 chr1 10318 . CCCCAA C 456.85 . AC=1;AF=0.000533;AN=1876;BaseQRankSum=0.354;ClippingRankSum=-1.626;DP=21573;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2247;MLEAC=1;MLEAF=0.000533;MQ=0.86;MQRankSum=0.212;QD=32.63;ReadPosRankSum=0.778;SOR=0.188 GT:AD:DP:PGT:PID:PL 0/0:16,7:23:.:.:0,0,319 chr1 10319 . C . . . AN=592;DP=22588 GT:AD:DP ./.:19:24 chr1 10320 . C CT 75.13 . AC=1;AF=0.0005302;AN=1886;BaseQRankSum=0.212;ClippingRankSum=-1.626;DP=22754;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2209;MLEAC=3;MLEAF=0.001591;MQ=0.93;MQRankSum=-0.354;QD=5.37;ReadPosRankSum=-0.354;SOR=0.188 GT:AD:DP:PGT:PID:PL 0/0:21,5:26:.:.:0,0,518 chr1 10321 . CAACCCT AAACCCT,C 3609.36 . AC=1,1;AF=0.000578,0.000578;AN=1730;BaseQRankSum=0.919;ClippingRankSum=-0.583;DP=21763;ExcessHet=3.0404;FS=0;InbreedingCoeff=0.1139;MLEAC=1,1;MLEAF=0.000578,0.000578;MQ=2.31;MQRankSum=0.727;QD=37.76;ReadPosRankSum=0.727;SOR=0.576 GT:AD:DP:PGT:PID:PL 0/0:16,4,4:20:.:.:0,0,411,0,411,411 chr1 10322 . A . . . AN=176;DP=22080 GT:AD:DP ./.:16:22 chr1 10323 . A . . . AN=262;DP=22355 GT:AD:DP ./.:14:24 chr1 10324 . C . . . AN=396;DP=22791 GT:AD:DP ./.:19:23 chr1 10325 . C . . . AN=536;DP=23339 GT:AD:DP ./.:20:25 chr1 10326 . C . . . AN=466;DP=23203 GT:AD:DP ./.:20:24 chr1 10327 . T C 2588.75 . AC=17;AF=0.021;AN=824;BaseQRankSum=0.736;ClippingRankSum=-0.421;DP=21952;ExcessHet=69.3203;FS=1.725;InbreedingCoeff=-0.2455;MLEAC=17;MLEAF=0.021;MQ=2.25;MQRankSum=0.421;QD=27.64;ReadPosRankSum=-0.736;SOR=0.155 GT:AD:DP:PGT:PID:PL 0/0:15,8:23:.:.:0,0,200 chr1 10328 . A . . . AN=60;DP=22075 GT:AD:DP ./.:14:23 chr1 10329 . AC A 104.73 . AC=1;AF=0.000821;AN=1218;BaseQRankSum=-0.922;ClippingRankSum=0.198;DP=22458;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2983;MLEAC=31;MLEAF=0.025;MQ=0.64;MQRankSum=-0.922;QD=14.96;ReadPosRankSum=-0.922;SOR=0.527 GT:AD:DP:PL ./.:11,13:24:. chr1 10330 . C A 249.83 . AC=4;AF=0.002663;AN=1502;BaseQRankSum=0.358;ClippingRankSum=1.23;DP=22430;ExcessHet=2.14748e+09;FS=13.239;InbreedingCoeff=-0.3036;MLEAC=52;MLEAF=0.035;MQ=1.19;MQRankSum=1.23;QD=10.86;ReadPosRankSum=0.358;SOR=0.018 GT:AD:DP:PGT:PID:PL 0/0:18,8:26:.:.:0,0,386 chr1 10331 . C . . . AN=102;DP=23575 GT:AD:DP ./.:18:24 chr1 10332 . C . . . AN=456;DP=23775 GT:AD:DP ./.:19:24 chr1 10333 . C T 1275.3 . AC=1;AF=0.0005747;AN=1740;BaseQRankSum=0.324;ClippingRankSum=1.62;DP=23222;ExcessHet=2.14748e+09;FS=2.754;InbreedingCoeff=-0.3125;MLEAC=1;MLEAF=0.0005747;MQ=1.34;MQRankSum=1.16;QD=29.43;ReadPosRankSum=1.44;SOR=2.303 GT:AD:DP:PGT:PID:PL 0/0:15,12:27:.:.:0,0,136 chr1 10334 . T A . . AC=0;AF=0;AN=24;DP=22701;ExcessHet=3.01;MQ=0.65 GT:AD:DP:PGT:PID ./.:9,15:24:.:. chr1 10335 . A . . . AN=64;DP=23149 GT:AD:DP ./.:13:22 chr1 10336 . A . . . AN=34;DP=23067 GT:AD:DP ./.:12:24 chr1 10337 . CCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTCGCGGTACCCTCAG CCCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTCGCGGTACCCTCAG,C . . AC=0,0;AF=0,0;AN=360;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=24001;ExcessHet=3.01;MQ=1.45;MQRankSum=0.804 GT:AD:DP:PGT:PID ./.:23,3,3:26:.:. chr1 10338 . C . . . AN=428;DP=24182 GT:AD:DP ./.:18:26 chr1 10339 . C . . . AN=304;DP=24010 GT:AD:DP ./.:21:26 chr1 10340 . T C . . AC=0;AF=0;AN=58;DP=23357;ExcessHet=3.01;MQ=0.54 GT:AD:DP:PGT:PID ./.:16,9:25:.:. chr1 10341 . A . . . AN=174;DP=23764 GT:AD:DP ./.:15:25 chr1 10342 . A . . . AN=86;DP=23630 GT:AD:DP ./.:14:27 chr1 10343 . C . . . AN=348;DP=24415 GT:AD:DP 0/0:24:26 chr1 10344 . C . . . AN=368;DP=24672 GT:AD:DP ./.:21:26 chr1 10345 . C . . . AN=306;DP=24463 GT:AD:DP ./.:21:26 chr1 10346 . T . . . AN=96;DP=23942 GT:AD:DP ./.:14:23 chr1 10347 . AACCCT A 932.95 . AC=3;AF=0.001987;AN=1510;BaseQRankSum=0.309;ClippingRankSum=-0.639;DP=24240;ExcessHet=2.14748e+09;FS=11.678;InbreedingCoeff=-0.2736;MLEAC=17;MLEAF=0.011;MQ=1.55;MQRankSum=-0.062;QD=25.21;ReadPosRankSum=-0.493;SOR=3.545 GT:AD:DP:PGT:PID:PL 0/0:16,7:23:.:.:0,0,185 chr1 10348 . A . . . AN=40;DP=24058 GT:AD:DP ./.:15:24 chr1 10349 . C . . . AN=176;DP=24866 GT:AD:DP ./.:17:25 chr1 10350 . C . . . AN=208;DP=25160 GT:AD:DP 0/0:22:24 chr1 10351 . C . . . AN=78;DP=24759 GT:AD:DP ./.:18:25 chr1 10352 . T A 207.96 . AC=8;AF=0.023;AN=346;BaseQRankSum=0.678;ClippingRankSum=-0.597;DP=24118;ExcessHet=8.5748;FS=1.922;InbreedingCoeff=-0.2449;MLEAC=43;MLEAF=0.124;MQ=1.54;MQRankSum=0.278;QD=9.04;ReadPosRankSum=0;SOR=0.209 GT:AD:DP:PL ./.:12,12:24:. chr1 10353 . A AAC . . AC=0;AF=0;AN=6;DP=24666;ExcessHet=3.01;MQ=0.87 GT:AD:DP ./.:9,14:23 chr1 10354 . C A 489.89 . AC=9;AF=0.006148;AN=1464;BaseQRankSum=-0.48;ClippingRankSum=0.48;DP=25045;ExcessHet=2.14748e+09;FS=8.181;InbreedingCoeff=-0.3158;MLEAC=98;MLEAF=0.067;MQ=2.6;MQRankSum=0.595;QD=4.62;ReadPosRankSum=0.48;SOR=0.179 GT:AD:DP:PL ./.:11,13:24:. chr1 10355 . C . . . AN=252;DP=25997 GT:AD:DP ./.:18:22 chr1 10356 . C . . . AN=268;DP=26017 GT:AD:DP ./.:20:23 chr1 10357 . T C,G . . AC=0,0;AF=0,0;AN=52;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=25371;ExcessHet=3.01;MQ=1.17;MQRankSum=0.804;ReadPosRankSum=1.47 GT:AD:DP ./.:20,4,4:24 chr1 10358 . A G,T . . AC=0,0;AF=0,0;AN=172;BaseQRankSum=0.747;ClippingRankSum=0.747;DP=25875;ExcessHet=3.01;MQ=1.27;MQRankSum=-0.747;ReadPosRankSum=0.747 GT:AD:DP ./.:16,8,8:24 chr1 10359 . A C . . AC=0;AF=0;AN=184;BaseQRankSum=1.03;ClippingRankSum=-1.026;DP=25950;ExcessHet=3.01;MQ=0.57;MQRankSum=1.03;ReadPosRankSum=-1.026 GT:AD:DP ./.:15,9:24 chr1 10360 . C G . . AC=0;AF=0;AN=288;DP=27357;ExcessHet=3.01;MQ=0.48 GT:AD:DP ./.:20,4:24 chr1 10361 . C G . . AC=0;AF=0;AN=382;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=27964;ExcessHet=3.01;MQ=0.66;MQRankSum=0.804;ReadPosRankSum=0.804 GT:AD:DP 0/0:23,1:24 chr1 10362 . C . . . AN=380;DP=28044 GT:AD:DP ./.:20:24 chr1 10363 . T C . . AC=0;AF=0;AN=222;BaseQRankSum=0.736;ClippingRankSum=-0.537;DP=27560;ExcessHet=3.01;MQ=0.88;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP ./.:18,6:24 chr1 10364 . A C,T . . AC=0,0;AF=0,0;AN=320;BaseQRankSum=-0.825;ClippingRankSum=-0.354;DP=28131;ExcessHet=3.01;MQ=1.08;MQRankSum=-0.589;ReadPosRankSum=-1.061 GT:AD:DP ./.:16,10,10:26 chr1 10365 . A . . . AN=282;DP=28154 GT:AD:DP ./.:19:28 chr1 10366 . C . . . AN=376;DP=29483 GT:AD:DP ./.:22:26 chr1 10367 . C T . . AC=0;AF=0;AN=416;BaseQRankSum=-1.733;ClippingRankSum=0.179;DP=29873;ExcessHet=3.01;MQ=1.01;MQRankSum=1.26;ReadPosRankSum=1.61 GT:AD:DP 0/0:25,1:26 chr1 10368 . C T . . AC=0;AF=0;AN=440;BaseQRankSum=-0.358;ClippingRankSum=-1.231;DP=29898;ExcessHet=3.01;MQ=0.48;MQRankSum=0.358;ReadPosRankSum=-1.231 GT:AD:DP 0/0:26,0:26 chr1 10369 . T G . . AC=0;AF=0;AN=274;BaseQRankSum=-0.747;ClippingRankSum=0.747;DP=29200;ExcessHet=3.01;MQ=0.49;MQRankSum=0.747;ReadPosRankSum=0.747 GT:AD:DP 0/0:24,2:26 chr1 10370 . A . . . AN=326;DP=29764 GT:AD:DP ./.:20:27 chr1 10371 . A C . . AC=0;AF=0;AN=332;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=29416;ExcessHet=3.01;MQ=1.23;MQRankSum=-0.736;ReadPosRankSum=-0.736 GT:AD:DP ./.:22,5:27 chr1 10372 . C . . . AN=394;DP=30851 GT:AD:DP 0/0:27:27 chr1 10373 . C . . . AN=414;DP=31229 GT:AD:DP ./.:25:27 chr1 10374 . C . . . AN=430;DP=31052 GT:AD:DP 0/0:26:27 chr1 10375 . T C . . AC=0;AF=0;AN=294;BaseQRankSum=0.48;ClippingRankSum=-1.067;DP=30201;ExcessHet=3.01;MQ=1.14;MQRankSum=0.898;ReadPosRankSum=-0.572 GT:AD:DP 0/0:24,3:27 chr1 10376 . A . . . AN=310;DP=30711 GT:AD:DP ./.:22:27 chr1 10377 . A . . . AN=292;DP=30356 GT:AD:DP ./.:19:27 chr1 10378 . C . . . AN=412;DP=31668 GT:AD:DP ./.:24:27 chr1 10379 . C A . . AC=0;AF=0;AN=466;BaseQRankSum=0.72;ClippingRankSum=0;DP=31981;ExcessHet=3.01;MQ=0.44;MQRankSum=-0.72;ReadPosRankSum=1.38 GT:AD:DP 0/0:27,0:27 chr1 10380 . C . . . AN=492;DP=31713 GT:AD:DP 0/0:25:27 chr1 10381 . T C . . AC=0;AF=0;AN=322;DP=30584;ExcessHet=3.01;MQ=0.67 GT:AD:DP ./.:24,5:29 chr1 10382 . A . . . AN=308;DP=31029 GT:AD:DP ./.:24:27 chr1 10383 . A . . . AN=186;DP=30748 GT:AD:DP ./.:22:27 chr1 10384 . C . . . AN=308;DP=31997 GT:AD:DP 0/0:26:27 chr1 10385 . C . . . AN=510;DP=32377 GT:AD:DP 0/0:27:27 chr1 10386 . C . . . AN=526;DP=31908 GT:AD:DP 0/0:27:28 chr1 10387 . T C . . AC=0;AF=0;AN=280;BaseQRankSum=0.762;ClippingRankSum=-0.736;DP=30161;ExcessHet=3.01;MQ=0.58;MQRankSum=-0.736;ReadPosRankSum=0.736 GT:AD:DP ./.:24,4:28 chr1 10388 . A T . . AC=0;AF=0;AN=292;DP=30144;ExcessHet=3.01;MQ=0.47 GT:AD:DP:PGT:PID ./.:27,3:30:.:. chr1 10389 . ACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC A,ACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC,ACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC . . AC=0,0,0;AF=0,0,0;AN=226;BaseQRankSum=0.731;ClippingRankSum=0.731;DP=29603;ExcessHet=3.01;MQ=0.95;MQRankSum=-0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID ./.:23,6,6,6:29:.:. chr1 10390 . CCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAA C 1989.61 . AC=18;AF=0.00989;AN=1820;BaseQRankSum=0.736;ClippingRankSum=0.198;DP=31399;ExcessHet=2.14748e+09;FS=27.678;InbreedingCoeff=-0.2628;MLEAC=27;MLEAF=0.015;MQ=3.16;MQRankSum=0.727;QD=15.79;ReadPosRankSum=0.493;SOR=0.437 GT:AD:DP:PGT:PID:PL 0/0:23,6:29:.:.:0,0,612 chr1 10391 . C . . . AN=366;DP=33506 GT:AD:DP ./.:26:29 chr1 10392 . C . . . AN=528;DP=33928 GT:AD:DP 0/0:27:29 chr1 10393 . C T . . AC=0;AF=0;AN=406;BaseQRankSum=0.731;ClippingRankSum=-0.731;DP=32877;ExcessHet=3.01;MQ=0.83;MQRankSum=0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID ./.:25,3:28:.:. chr1 10394 . T C . . AC=0;AF=0;AN=160;BaseQRankSum=-1.645;ClippingRankSum=0.31;DP=31433;ExcessHet=3.01;MQ=1.24;MQRankSum=0.262;ReadPosRankSum=-2.393 GT:AD:DP:PGT:PID ./.:21,7:28:.:. chr1 10395 . A . . . AN=180;DP=32229 GT:AD:DP ./.:20:28 chr1 10396 . AC A . . AC=0;AF=0;AN=220;BaseQRankSum=0.731;ClippingRankSum=0.731;DP=31887;ExcessHet=3.01;MQ=0.91;MQRankSum=-0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID ./.:19,7:26:.:. chr1 10397 . CCCCTAA C 658.74 . AC=8;AF=0.004301;AN=1860;BaseQRankSum=0.736;ClippingRankSum=0.358;DP=33161;ExcessHet=2.14748e+09;FS=14.46;InbreedingCoeff=-0.244;MLEAC=7;MLEAF=0.003763;MQ=2.55;MQRankSum=0.731;QD=9.98;ReadPosRankSum=-0.709;SOR=0.786 GT:AD:DP:PGT:PID:PL 0/0:21,7:28:.:.:0,0,451 chr1 10398 . C G . . AC=0;AF=0;AN=494;DP=35588;ExcessHet=3.01;MQ=0.52 GT:AD:DP:PGT:PID 0/0:27,1:28:.:. chr1 10399 . C . . . AN=684;DP=35790 GT:AD:DP ./.:26:28 chr1 10400 . C T . . AC=0;AF=0;AN=542;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=34991;ExcessHet=3.01;MQ=0.51;MQRankSum=0.736;ReadPosRankSum=0.736 GT:AD:DP:PGT:PID ./.:23,4:27:.:. chr1 10401 . TA T . . AC=0;AF=0;AN=384;BaseQRankSum=0.731;ClippingRankSum=0.731;DP=33949;ExcessHet=3.01;MQ=0.39;MQRankSum=-0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID ./.:22,5:27:.:. chr1 10402 . A . . . AN=382;DP=34851 GT:AD:DP ./.:22:27 chr1 10403 . A ACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC 2085.08 . AC=6;AF=0.00339;AN=1770;BaseQRankSum=-0.296;ClippingRankSum=0.736;DP=34164;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2531;MLEAC=4;MLEAF=0.00226;MQ=1.08;MQRankSum=1.88;QD=30.09;ReadPosRankSum=-2.27;SOR=1.118 GT:AD:DP:PL 0/0:24,3:27:0,10,557 chr1 10404 . CCCTAA C 107.81 . AC=4;AF=0.002086;AN=1918;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=35988;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2033;MLEAC=9;MLEAF=0.004692;MQ=0.51;MQRankSum=-0.736;QD=13.48;ReadPosRankSum=-0.736;SOR=0.693 GT:AD:DP:PL 0/0:27,0:27:0,30,450 chr1 10405 . C . . . AN=910;DP=36504 GT:AD:DP 0/0:27:27 chr1 10406 . C . . . AN=842;DP=35903 GT:AD:DP 0/0:25:27 chr1 10407 . TAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTA CAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTA,TACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTA,T . . AC=0,0,0;AF=0,0,0;AN=568;BaseQRankSum=0.358;ClippingRankSum=-0.727;DP=34596;ExcessHet=3.01;MQ=0.79;MQRankSum=0.727;ReadPosRankSum=-0.727 GT:AD:DP:PGT:PID ./.:23,4,4,4:27:.:. chr1 10408 . A T . . AC=0;AF=0;AN=512;BaseQRankSum=-0.742;ClippingRankSum=-0.742;DP=35492;ExcessHet=3.01;MQ=0.48;MQRankSum=0.742;ReadPosRankSum=-0.742 GT:AD:DP:PGT:PID 0/0:26,1:27:.:. chr1 10409 . A AC 578.59 . AC=4;AF=0.002114;AN=1892;BaseQRankSum=1.03;ClippingRankSum=1.5;DP=34914;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2219;MLEAC=4;MLEAF=0.002114;MQ=0.99;MQRankSum=0.198;QD=31.26;ReadPosRankSum=1.59;SOR=0.569 GT:AD:DP:PGT:PID:PL 0/0:26,1:27:.:.:0,30,450 chr1 10410 . CCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAA C,CCCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAA . . AC=0,0;AF=0,0;AN=1044;BaseQRankSum=1.05;ClippingRankSum=0.203;DP=35999;ExcessHet=3.01;MQ=1.92;MQRankSum=0.182;ReadPosRankSum=0.704 GT:AD:DP 0/0:27,0,0:27 chr1 10411 . C . . . AN=1282;DP=36695 GT:AD:DP 0/0:27:27 chr1 10412 . C . . . AN=1248;DP=36123 GT:AD:DP 0/0:27:27 chr1 10413 . T . . . AN=936;DP=34901 GT:AD:DP ./.:25:27 chr1 10414 . A AACCCT,T . . AC=0,0;AF=0,0;AN=952;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=35709;ExcessHet=3.01;MQ=0.42;MQRankSum=0.727;ReadPosRankSum=-0.727 GT:AD:DP 0/0:27,0,0:27 chr1 10415 . A G,T,AC,C . . AC=0,0,0,0;AF=0,0,0,0;AN=946;BaseQRankSum=0;ClippingRankSum=-0.348;DP=35278;ExcessHet=3.01;MQ=0.92;MQRankSum=1.39;ReadPosRankSum=1.59 GT:AD:DP:PGT:PID 0/0:26,2,2,2,2:28:.:. chr1 10416 . C . . . AN=1346;DP=36248 GT:AD:DP 0/0:28:28 chr1 10417 . C . . . AN=1494;DP=36738 GT:AD:DP 0/0:27:28 chr1 10418 . C . . . AN=1570;DP=36165 GT:AD:DP 0/0:27:28 chr1 10419 . TA CA,T . . AC=0,0;AF=0,0;AN=1440;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=34862;ExcessHet=3.01;MQ=1.26;MQRankSum=-0.572;ReadPosRankSum=0.572 GT:AD:DP 0/0:26,2,2:28 chr1 10420 . AACCCT A . . AC=0;AF=0;AN=1522;BaseQRankSum=0.392;ClippingRankSum=-0.771;DP=35646;ExcessHet=3.01;MQ=1.77;MQRankSum=0.23;ReadPosRankSum=-1.507 GT:AD:DP 0/0:28,0:28 chr1 10421 . A AC,G,C,ACC . . AC=0,0,0,0;AF=0,0,0,0;AN=1472;BaseQRankSum=0.067;ClippingRankSum=0.967;DP=35342;ExcessHet=3.01;MQ=1.36;MQRankSum=0.572;ReadPosRankSum=1.61 GT:AD:DP:PGT:PID 0/0:26,2,2,2,2:28:.:. chr1 10422 . CCCTAACCCTAA CCCCTAA,GCCTAACCCTAA,C . . AC=0,0,0;AF=0,0,0;AN=1652;BaseQRankSum=-1.537;ClippingRankSum=-0.817;DP=35753;ExcessHet=3.01;MQ=3.1;MQRankSum=-0.72;ReadPosRankSum=-1.38 GT:AD:DP 0/0:28,0,0,0:28 chr1 10423 . C . . . AN=1838;DP=36352 GT:AD:DP 0/0:27:28 chr1 10424 . C T . . AC=0;AF=0;AN=1846;BaseQRankSum=-0.751;ClippingRankSum=0.751;DP=35693;ExcessHet=3.01;MQ=0.5;MQRankSum=0.751;ReadPosRankSum=0.751 GT:AD:DP ./.:26,3:29 chr1 10425 . TA T,CA . . AC=0,0;AF=0,0;AN=1724;BaseQRankSum=0.72;ClippingRankSum=0.034;DP=34437;ExcessHet=3.01;MQ=1.48;MQRankSum=0.849;ReadPosRankSum=1.38 GT:AD:DP:PGT:PID ./.:25,4,4:29:.:. chr1 10426 . A G,C . . AC=0,0;AF=0,0;AN=1778;BaseQRankSum=-1.014;ClippingRankSum=-0.986;DP=35076;ExcessHet=3.01;MQ=1.56;MQRankSum=2.14;ReadPosRankSum=0 GT:AD:DP:PGT:PID 0/0:29,0,0:29:.:. chr1 10427 . A AC 148.83 . AC=3;AF=0.001558;AN=1926;BaseQRankSum=0.358;ClippingRankSum=0.72;DP=34699;ExcessHet=14.3006;FS=12.438;InbreedingCoeff=-0.0383;MLEAC=3;MLEAF=0.001558;MQ=1.73;MQRankSum=0.572;QD=6.2;ReadPosRankSum=1.23;SOR=0.732 GT:AD:DP:PGT:PID:PL 0/0:25,1:26:.:.:0,18,270 chr1 10428 . CCCTAA C . . AC=0;AF=0;AN=1734;BaseQRankSum=-0.72;ClippingRankSum=-0.72;DP=35022;ExcessHet=3.01;MQ=0.45;MQRankSum=0;ReadPosRankSum=1.38 GT:AD:DP:PGT:PID 0/0:27,1:28:.:. chr1 10429 . C G . . AC=0;AF=0;AN=1822;DP=35230;ExcessHet=3.01;MQ=0.75 GT:AD:DP 0/0:27,1:28 chr1 10430 . C CT . . AC=0;AF=0;AN=1790;DP=34463;ExcessHet=3.01;MQ=0.73 GT:AD:DP:PGT:PID ./.:25,3:28:.:. chr1 10431 . TAACCCTA AAACCCTA,TTA,TACCCTA,CAACCCTA,T,GAACCCTA,TAAACCCTA . . AC=0,0,0,0,0,0,0;AF=0,0,0,0,0,0,0;AN=1614;BaseQRankSum=0.447;ClippingRankSum=-0.805;DP=32949;ExcessHet=3.01;MQ=3.07;MQRankSum=0.358;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID 0/0:27,1,1,1,1,1,1,1:28:.:. chr1 10432 . AACCCTAAC TACCCTAAC,A,CACCCTAAC . . AC=0,0,0;AF=0,0,0;AN=1700;BaseQRankSum=-0.057;ClippingRankSum=0.964;DP=33492;ExcessHet=3.01;MQ=1.59;MQRankSum=1.27;ReadPosRankSum=-0.587 GT:AD:DP:PGT:PID 0/0:27,0,0,0:27:.:. chr1 10433 . ACCCTAAC ACCCCTAAC,A,GCCCTAAC,ACCCTTAACCCCTAAC . . AC=0,0,0,0;AF=0,0,0,0;AN=1450;BaseQRankSum=1.23;ClippingRankSum=-0.358;DP=32963;ExcessHet=3.01;MQ=1.59;MQRankSum=-0.198;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID 0/0:25,1,1,1,1:26:.:. chr1 10434 . CCCT C,GCCT . . AC=0,0;AF=0,0;AN=1510;BaseQRankSum=0;ClippingRankSum=0.358;DP=33018;ExcessHet=3.01;MQ=0.61;MQRankSum=-0.358;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID 0/0:25,1,1:26:.:. chr1 10435 . C . . . AN=1884;DP=32924 GT:AD:DP 0/0:26:26 chr1 10436 . C T 298.7 . AC=3;AF=0.001556;AN=1928;BaseQRankSum=-0.742;ClippingRankSum=0.493;DP=31863;ExcessHet=4.1842;FS=1.095;InbreedingCoeff=-0.0166;MLEAC=2;MLEAF=0.001037;MQ=1.51;MQRankSum=0.742;QD=21.34;ReadPosRankSum=-0.358;SOR=0.529 GT:AD:DP:PGT:PID:PL 0/0:26,0:26:.:.:0,18,270 chr1 10437 . TAACCCC GAACCCC,TC,T,CAACCCC,TACCCC . . AC=0,0,0,0,0;AF=0,0,0,0,0;AN=1554;BaseQRankSum=0.742;ClippingRankSum=0.742;DP=30326;ExcessHet=3.01;MQ=1.5;MQRankSum=0.736;ReadPosRankSum=0.804 GT:AD:DP:PGT:PID ./.:22,4,4,4,4,4:26:.:. chr1 10438 . AACCCCT TACCCCT,CACCCCT,AGCCCTACCCCT,ACCCT,A . . AC=0,0,0,0,0;AF=0,0,0,0,0;AN=1580;BaseQRankSum=0.067;ClippingRankSum=0.742;DP=30288;ExcessHet=3.01;MQ=1.45;MQRankSum=-0.742;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID ./.:20,5,5,5,5,5:25:.:. chr1 10439 . ACC AC,A 62672.6 . AC=286,4;AF=0.149,0.002083;AN=1920;BaseQRankSum=-0.361;ClippingRankSum=0;DP=25898;ExcessHet=0.0065;FS=7.168;InbreedingCoeff=0.1075;MLEAC=273,4;MLEAF=0.142,0.002083;MQ=14.01;MQRankSum=0.358;QD=15.25;ReadPosRankSum=-0.358;SOR=1.287 GT:AD:DP:PGT:PID:PL 0/0:1,0,0:1:.:.:0,1,2,1,2,2 chr1 10440 . C CCCTAACCCTAA,A,CCCTTAA 5329.45 . AC=2,30,1;AF=0.001049,0.016,0.0005247;AN=1906;BaseQRankSum=-0.65;ClippingRankSum=-0.311;DP=28314;ExcessHet=8.2859;FS=0;InbreedingCoeff=0.2661;MLEAC=1,26,1;MLEAF=0.0005247,0.014,0.0005247;MQ=6.3;MQRankSum=0.269;QD=12.54;ReadPosRankSum=0.085;SOR=0.56 GT:AD:DP:PGT:PID:PL ./.:0,0,0,0:1:.:.:. chr1 10441 . CCCTA C 3290.1 . AC=2;AF=0.001094;AN=1828;BaseQRankSum=-0.727;ClippingRankSum=-0.358;DP=28140;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2599;MLEAC=2;MLEAF=0.001094;MQ=3.08;MQRankSum=0.343;QD=29;ReadPosRankSum=0.358;SOR=0.69 GT:AD:DP:PGT:PID:PL 0/0:18,7:25:.:.:0,0,449 chr1 10442 . C CT 163.39 . AC=2;AF=0.001205;AN=1660;BaseQRankSum=-0.358;ClippingRankSum=0.731;DP=27104;ExcessHet=30.7241;FS=0;InbreedingCoeff=-0.1081;MLEAC=2;MLEAF=0.001205;MQ=0.87;MQRankSum=-0.589;QD=20.42;ReadPosRankSum=-0.118;SOR=0.446 GT:AD:DP:PGT:PID:PL 0/0:20,3:23:.:.:0,0,572 chr1 10443 . CT TT,C 3668.13 . AC=26,6;AF=0.014,0.003293;AN=1822;BaseQRankSum=-0.736;ClippingRankSum=0;DP=25038;ExcessHet=0.1326;FS=20.792;InbreedingCoeff=0.0924;MLEAC=26,4;MLEAF=0.014,0.002195;MQ=3.82;MQRankSum=0.198;QD=15.1;ReadPosRankSum=0.322;SOR=0.201 GT:AD:DP:PGT:PID:PL 0/0:17,5,5:22:.:.:0,0,392,0,392,392 chr1 10444 . TA AA,T 3350.54 . AC=10,8;AF=0.005537,0.00443;AN=1806;BaseQRankSum=-0.736;ClippingRankSum=0.134;DP=23714;ExcessHet=0.0014;FS=0;InbreedingCoeff=0.1084;MLEAC=8,5;MLEAF=0.00443,0.002769;MQ=2.4;MQRankSum=-0.296;QD=26.28;ReadPosRankSum=-0.668;SOR=0.551 GT:AD:DP:PGT:PID:PL 0/0:18,4,4:22:.:.:0,0,401,0,401,401 chr1 10445 . AACCCT A 234.04 . AC=4;AF=0.002328;AN=1718;BaseQRankSum=-0.736;ClippingRankSum=-0.48;DP=23566;ExcessHet=96.1362;FS=1.559;InbreedingCoeff=-0.1452;MLEAC=4;MLEAF=0.002328;MQ=1.36;MQRankSum=0.736;QD=30.19;ReadPosRankSum=-0.736;SOR=0.384 GT:AD:DP:PGT:PID:PL 0/0:18,4:22:.:.:0,0,490 chr1 10446 . A G 691.48 . AC=2;AF=0.00117;AN=1710;BaseQRankSum=-0.747;ClippingRankSum=0.736;DP=23126;ExcessHet=100.32;FS=1.852;InbreedingCoeff=-0.1482;MLEAC=1;MLEAF=0.0005848;MQ=1.55;MQRankSum=0.747;QD=29.45;ReadPosRankSum=-0.496;SOR=0.307 GT:AD:DP:PGT:PID:PL 0/0:19,3:22:.:.:0,0,448 chr1 10447 . CCCTAA C 313.96 . AC=9;AF=0.0053;AN=1698;BaseQRankSum=0.067;ClippingRankSum=0.406;DP=22835;ExcessHet=16.9094;FS=14.962;InbreedingCoeff=-0.0835;MLEAC=8;MLEAF=0.004711;MQ=2.62;MQRankSum=0.116;QD=11.21;ReadPosRankSum=-0.736;SOR=0.135 GT:AD:DP:PGT:PID:PL 0/0:19,3:22:.:.:0,0,590 chr1 10448 . C A . . AC=0;AF=0;AN=1546;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=22503;ExcessHet=3.01;MQ=0.3;MQRankSum=0.804;ReadPosRankSum=0.804 GT:AD:DP:PGT:PID 0/0:21,1:22:.:. chr1 10449 . C CT . . AC=0;AF=0;AN=1406;DP=21657;ExcessHet=3.01;MQ=0.47 GT:AD:DP:PGT:PID 0/0:20,1:21:.:. chr1 10450 . T C,G 1389.18 . AC=6,4;AF=0.003401,0.002268;AN=1764;BaseQRankSum=0;ClippingRankSum=0.358;DP=20544;ExcessHet=0.0016;FS=5.379;InbreedingCoeff=0.0886;MLEAC=4,3;MLEAF=0.002268,0.001701;MQ=2.62;MQRankSum=0;QD=34.04;ReadPosRankSum=0.736;SOR=0.341 GT:AD:DP:PGT:PID:PL 0/0:20,1,1:21:.:.:0,18,270,18,270,270 chr1 10451 . A T 782.86 . AC=2;AF=0.001159;AN=1726;BaseQRankSum=-0.731;ClippingRankSum=-0.198;DP=20384;ExcessHet=74.6225;FS=11.805;InbreedingCoeff=-0.1287;MLEAC=2;MLEAF=0.001159;MQ=2.51;MQRankSum=0.198;QD=29.82;ReadPosRankSum=0.727;SOR=0.064 GT:AD:DP:PGT:PID:PL 0/0:19,2:21:.:.:0,10,515 chr1 10452 . A C,G 497.17 . AC=8,2;AF=0.004662,0.001166;AN=1716;BaseQRankSum=-0.747;ClippingRankSum=0.804;DP=19813;ExcessHet=0;FS=4.961;InbreedingCoeff=0.0888;MLEAC=5,1;MLEAF=0.002914,0.0005828;MQ=1.57;MQRankSum=0.804;QD=19.89;ReadPosRankSum=0.804;SOR=0.148 GT:AD:DP:PGT:PID:PL 0/0:19,2,2:21:.:.:0,4,508,4,508,508 chr1 10453 . CCCTAA C,GCCTAA,ACCTAA . . AC=0,0,0;AF=0,0,0;AN=1434;BaseQRankSum=-0.736;ClippingRankSum=0.736;DP=19420;ExcessHet=3.01;MQ=2.66;MQRankSum=0.482;ReadPosRankSum=0 GT:AD:DP:PGT:PID 0/0:19,0,0,0:19:.:. chr1 10454 . C T . . AC=0;AF=0;AN=1534;BaseQRankSum=-1.041;ClippingRankSum=-1.561;DP=19102;ExcessHet=3.01;MQ=0.92;MQRankSum=0.173;ReadPosRankSum=-1.041 GT:AD:DP 0/0:19,0:19 chr1 10455 . C A . . AC=0;AF=0;AN=1512;BaseQRankSum=-1.666;ClippingRankSum=0.067;DP=18360;ExcessHet=3.01;MQ=0.47;MQRankSum=0.762;ReadPosRankSum=0.067 GT:AD:DP:PGT:PID 0/0:19,0:19:.:. chr1 10456 . T C,TG . . AC=0,0;AF=0,0;AN=1214;BaseQRankSum=-1.739;ClippingRankSum=0.158;DP=17536;ExcessHet=3.01;MQ=2.14;MQRankSum=0.791;ReadPosRankSum=-1.739 GT:AD:DP:PGT:PID 0/0:18,0,0:18:.:. chr1 10457 . A T 429.49 . AC=4;AF=0.002317;AN=1726;BaseQRankSum=-0.736;ClippingRankSum=0;DP=17125;ExcessHet=42.053;FS=4.627;InbreedingCoeff=-0.1057;MLEAC=3;MLEAF=0.001738;MQ=1.44;MQRankSum=0.736;QD=33.74;ReadPosRankSum=0.198;SOR=0.162 GT:AD:DP:PGT:PID:PL 0/0:18,0:18:.:.:0,18,270 chr1 10458 . A . . . AN=1320;DP=16611 GT:AD:DP 0/0:17:18 chr1 10459 . C A 33.68 . AC=1;AF=0.0005869;AN=1704;BaseQRankSum=-0.736;ClippingRankSum=-0.736;DP=16189;ExcessHet=27.4097;FS=0;InbreedingCoeff=-0.0919;MLEAC=1;MLEAF=0.0005869;MQ=0.39;MQRankSum=-0.736;QD=11.23;ReadPosRankSum=-0.736;SOR=0.223 GT:AD:DP:PGT:PID:PL 0/0:15,2:17:.:.:0,0,421 chr1 10460 . C G . . AC=0;AF=0;AN=1560;BaseQRankSum=-1.026;ClippingRankSum=-1.026;DP=15729;ExcessHet=3.01;MQ=0.35;MQRankSum=-1.026;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID 0/0:15,0:15:.:. chr1 10461 . C CT,T . . AC=0,0;AF=0,0;AN=1514;BaseQRankSum=-1.387;ClippingRankSum=0;DP=14975;ExcessHet=3.01;MQ=1.64;MQRankSum=-0.572;ReadPosRankSum=0 GT:AD:DP:PGT:PID 0/0:13,1,1:14:.:. chr1 10462 . T G,C . . AC=0,0;AF=0,0;AN=1124;BaseQRankSum=-1.231;ClippingRankSum=0.358;DP=14079;ExcessHet=3.01;MQ=1.16;MQRankSum=-0.358;ReadPosRankSum=-0.727 GT:AD:DP:PGT:PID 0/0:11,1,1:12:.:. chr1 10463 . AACCCTCGCGGT A . . AC=0;AF=0;AN=1164;DP=13304;ExcessHet=3.01;MQ=1.2 GT:AD:DP:PGT:PID 0/0:10,1:11:.:. chr1 10464 . A . . . AN=1378;DP=12317 GT:AD:DP 0/0:9:9 chr1 10465 . CCCTCGCGGTA CCGCGGTA,C . . AC=0,0;AF=0,0;AN=1356;DP=11631;ExcessHet=3.01;MQ=1.34 GT:AD:DP:PGT:PID ./.:9,1,1:10:.:. chr1 10466 . C T . . AC=0;AF=0;AN=1462;DP=10700;ExcessHet=3.01;MQ=0.87 GT:AD:DP:PGT:PID 0/0:10,0:10:.:. chr1 10467 . CTCGCGG C 91.48 . AC=1;AF=0.0005754;AN=1738;BaseQRankSum=0.839;ClippingRankSum=-0.71;DP=9660;ExcessHet=17.792;FS=15.091;InbreedingCoeff=-0.09;MLEAC=1;MLEAF=0.0005754;MQ=1.82;MQRankSum=-1.097;QD=6.53;ReadPosRankSum=-2.905;SOR=3.901 GT:AD:DP:PGT:PID:PL 0/0:9,0:9:.:.:0,18,270 chr1 10468 . T TAACCCTAACCCTAACCCCTAACCC 2053.01 . AC=2;AF=0.001153;AN=1734;BaseQRankSum=0.736;ClippingRankSum=0.358;DP=8545;ExcessHet=72.7396;FS=0;InbreedingCoeff=-0.1633;MLEAC=1;MLEAF=0.0005767;MQ=4.39;MQRankSum=-0.347;QD=33.93;ReadPosRankSum=-1.231;SOR=0.872 GT:AD:DP:PGT:PID:PL 0/0:8,1:9:.:.:0,0,193 chr1 10469 . C G 46.14 . AC=1;AF=0.0007899;AN=1266;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=7714;ExcessHet=95.6797;FS=3.522;InbreedingCoeff=-0.239;MLEAC=5;MLEAF=0.003949;MQ=1.42;MQRankSum=0.736;QD=15.38;ReadPosRankSum=0.736;SOR=2.272 GT:AD:DP:PGT:PID:PL 0/0:5,2:7:.:.:0,0,72 chr1 10470 . G C . . AC=0;AF=0;AN=446;BaseQRankSum=2.33;ClippingRankSum=-0.454;DP=6910;ExcessHet=3.01;MQ=2.89;MQRankSum=1.46;ReadPosRankSum=-0.298 GT:AD:DP:PGT:PID ./.:6,1:7:.:. chr1 10471 . CGG C . . AC=0;AF=0;AN=1054;BaseQRankSum=1.51;ClippingRankSum=0.736;DP=6649;ExcessHet=3.01;MQ=2.88;MQRankSum=0.892;ReadPosRankSum=-0.736 GT:AD:DP:PGT:PID ./.:6,1:7:.:. chr1 10472 . G . . . AN=696;DP=6122 GT:AD:DP ./.:6:7 chr1 10473 . G A 137.73 . AC=5;AF=0.003338;AN=1498;BaseQRankSum=2.05;ClippingRankSum=1.47;DP=6021;ExcessHet=32.8816;FS=1.489;InbreedingCoeff=-0.1331;MLEAC=8;MLEAF=0.00534;MQ=2.47;MQRankSum=0.906;QD=4.17;ReadPosRankSum=1.47;SOR=0.709 GT:AD:DP:PL 0/0:6,0:6:0,18,171 chr1 10474 . T A,TA,TAACCCCTAACCCTA,TAACCCTAACCCTA . . AC=0,0,0,0;AF=0,0,0,0;AN=1030;BaseQRankSum=0.742;ClippingRankSum=-0.736;DP=5833;ExcessHet=3.01;MQ=4.21;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:PGT:PID 0/0:6,0,0,0,0:6:.:. chr1 10475 . A AAC 93.58 . AC=1;AF=0.0006083;AN=1644;BaseQRankSum=1.49;ClippingRankSum=0.968;DP=5720;ExcessHet=18.9519;FS=15.091;InbreedingCoeff=-0.113;MLEAC=1;MLEAF=0.0006083;MQ=2.19;MQRankSum=-0.452;QD=6.68;ReadPosRankSum=-0.751;SOR=3.901 GT:AD:DP:PGT:PID:PL 0/0:6,0:6:.:.:0,18,182 chr1 10476 . C A . . AC=0;AF=0;AN=1116;BaseQRankSum=-1.423;ClippingRankSum=-1.423;DP=5735;ExcessHet=3.01;MQ=1.82;MQRankSum=-0.474 GT:AD:DP:PGT:PID 0/0:6,0:6:.:. chr1 10477 . C . . . AN=1304;DP=5822 GT:AD:DP 0/0:6:6 chr1 10478 . C . . . AN=1434;DP=5712 GT:AD:DP 0/0:6:6 chr1 10479 . T . . . AN=1096;DP=5373 GT:AD:DP 0/0:6:6 chr1 10480 . C A . . AC=0;AF=0;AN=1440;BaseQRankSum=0.751;ClippingRankSum=0.751;DP=5515;ExcessHet=3.01;MQ=3.5;MQRankSum=0.272;ReadPosRankSum=-0.751 GT:AD:DP:PGT:PID 0/0:6,0:6:.:. chr1 10481 . A . . . AN=1304;DP=5354 GT:AD:DP 0/0:6:6 chr1 10482 . G C . . AC=0;AF=0;AN=1290;BaseQRankSum=-0.751;ClippingRankSum=0.421;DP=5306;ExcessHet=3.01;MQ=3.35;MQRankSum=0.299;ReadPosRankSum=-2.793 GT:AD:DP:PGT:PID 0/0:6,0:6:.:. chr1 10483 . C A . . AC=0;AF=0;AN=1478;BaseQRankSum=1.03;ClippingRankSum=0;DP=5438;ExcessHet=3.01;MQ=0.8;MQRankSum=1.03;ReadPosRankSum=1.03 GT:AD:DP 0/0:6,0:6 chr1 10484 . C . . . AN=1550;DP=5374 GT:AD:DP 0/0:6:6 chr1 10485 . G . . . AN=1338;DP=5163 GT:AD:DP 0/0:6:6 chr1 10486 . G . . . AN=1392;DP=5096 GT:AD:DP 0/0:6:6 chr1 10487 . C . . . AN=1536;DP=5208 GT:AD:DP 0/0:6:6 chr1 10488 . C . . . AN=1524;DP=5178 GT:AD:DP 0/0:6:6 chr1 10489 . C . . . AN=1550;DP=5167 GT:AD:DP 0/0:6:6 chr1 10490 . G . . . AN=1468;DP=4945 GT:AD:DP 0/0:6:6 chr1 10491 . C . . . AN=1618;DP=5095 GT:AD:DP 0/0:6:6 chr1 10492 . C T 924.66 . AC=32;AF=0.02;AN=1598;BaseQRankSum=-0.358;ClippingRankSum=-0.198;DP=5075;ExcessHet=0.0046;FS=0.671;InbreedingCoeff=-0.015;MLEAC=34;MLEAF=0.021;MQ=4.44;MQRankSum=0.358;QD=7.28;ReadPosRankSum=0;SOR=0.592 GT:AD:DP:PGT:PID:PL 0/0:6,0:6:.:.:0,18,167 chr1 10493 . C . . . AN=1578;DP=5035 GT:AD:DP 0/0:6:6 chr1 10494 . G . . . AN=1494;DP=4852 GT:AD:DP 0/0:6:6 chr1 10495 . C . . . AN=1572;DP=4936 GT:AD:DP 0/0:6:6 chr1 10496 . C . . . AN=1624;DP=4947 GT:AD:DP 0/0:6:6 chr1 10497 . C T . . AC=0;AF=0;AN=1620;DP=4915;ExcessHet=3.01;MQ=0.42 GT:AD:DP 0/0:6,0:6 chr1 10498 . G T . . AC=0;AF=0;AN=1556;DP=4804;ExcessHet=3.01;MQ=0.68 GT:AD:DP 0/0:6,0:6 chr1 10499 . G . . . AN=1570;DP=4780 GT:AD:DP 0/0:6:6 chr1 10500 . G . . . AN=1578;DP=4732 GT:AD:DP 0/0:6:6 chr1 10501 . T . . . AN=1370;DP=4438 GT:AD:DP 0/0:6:6 chr1 10502 . C . . . AN=1610;DP=4748 GT:AD:DP 0/0:6:6 chr1 10503 . T C . . AC=0;AF=0;AN=1492;BaseQRankSum=1.23;ClippingRankSum=0.358;DP=4545;ExcessHet=3.01;MQ=0.79;MQRankSum=0.358;ReadPosRankSum=0.358 GT:AD:DP:PGT:PID 0/0:6,0:6:.:. chr1 10504 . G C 52.81 . AC=1;AF=0.000601;AN=1664;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=4606;ExcessHet=3.4244;FS=0;InbreedingCoeff=-0.0614;MLEAC=1;MLEAF=0.000601;MQ=0.97;MQRankSum=0.727;QD=13.2;ReadPosRankSum=0.727;SOR=1.609 GT:AD:DP:PL 0/0:6,0:6:0,12,180 chr1 10505 . A . . . AN=1534;DP=4492 GT:AD:DP 0/0:6:6 chr1 10506 . C . . . AN=1628;DP=4589 GT:AD:DP 0/0:6:6 chr1 10507 . C . . . AN=1610;DP=4559 GT:AD:DP 0/0:5:5 chr1 10508 . T . . . AN=1428;DP=4323 GT:AD:DP 0/0:4:4 chr1 10509 . G . . . AN=1574;DP=4454 GT:AD:DP 0/0:4:4 chr1 10510 . A . . . AN=1540;DP=4381 GT:AD:DP 0/0:4:4 chr1 10511 . G . . . AN=1596;DP=4409 GT:AD:DP 0/0:4:4 chr1 10512 . G . . . AN=1602;DP=4414 GT:AD:DP 0/0:4:4 chr1 10513 . A . . . AN=1512;DP=4266 GT:AD:DP 0/0:4:4 chr1 10514 . G . . . AN=1594;DP=4340 GT:AD:DP 0/0:4:4 chr1 10515 . A . . . AN=1480;DP=4213 GT:AD:DP 0/0:4:4 chr1 10516 . A . . . AN=1556;DP=4285 GT:AD:DP 0/0:4:4 chr1 10517 . C . . . AN=1622;DP=4272 GT:AD:DP 0/0:4:4 chr1 10518 . T . . . AN=1478;DP=4143 GT:AD:DP 0/0:4:4 chr1 10519 . G . . . AN=1526;DP=4202 GT:AD:DP 0/0:4:4 chr1 10520 . T . . . AN=1540;DP=4132 GT:AD:DP 0/0:4:4 chr1 10521 . G . . . AN=1604;DP=4133 GT:AD:DP 0/0:4:4 chr1 10522 . C . . . AN=1616;DP=4178 GT:AD:DP 0/0:4:4 chr1 10523 . T . . . AN=1546;DP=4076 GT:AD:DP 0/0:3:3 chr1 10524 . C . . . AN=1592;DP=4113 GT:AD:DP 0/0:3:3 chr1 10525 . C . . . AN=1602;DP=4139 GT:AD:DP 0/0:3:3 chr1 10526 . G . . . AN=1576;DP=4034 GT:AD:DP 0/0:3:3 chr1 10527 . C . . . AN=1594;DP=4054 GT:AD:DP 0/0:3:3 chr1 10528 . C . . . AN=1590;DP=4047 GT:AD:DP 0/0:3:3 chr1 10529 . T . . . AN=1524;DP=3967 GT:AD:DP 0/0:3:3 chr1 10530 . T . . . AN=1534;DP=3948 GT:AD:DP 0/0:3:3 chr1 10531 . C . . . AN=1610;DP=3971 GT:AD:DP 0/0:3:3 chr1 10532 . A . . . AN=1484;DP=3857 GT:AD:DP 0/0:3:3 chr1 10533 . G . . . AN=1488;DP=3853 GT:AD:DP 0/0:3:3 chr1 10534 . A . . . AN=1532;DP=3811 GT:AD:DP 0/0:3:3 chr1 10535 . G . . . AN=1592;DP=3810 GT:AD:DP 0/0:3:3 chr1 10536 . T . . . AN=1452;DP=3709 GT:AD:DP 0/0:3:3 chr1 10537 . A . . . AN=1546;DP=3718 GT:AD:DP 0/0:3:3 chr1 10538 . C . . . AN=1622;DP=3764 GT:AD:DP 0/0:2:2 chr1 10539 . C . . . AN=1618;DP=3726 GT:AD:DP 0/0:2:2 chr1 10540 . A . . . AN=1520;DP=3634 GT:AD:DP 0/0:2:2 chr1 10541 . C . . . AN=1616;DP=3670 GT:AD:DP 0/0:2:2 chr1 10542 . C T . . AC=0;AF=0;AN=1556;BaseQRankSum=1.03;ClippingRankSum=-1.026;DP=3668;ExcessHet=3.01;MQ=0.69;MQRankSum=-1.026;ReadPosRankSum=-1.026 GT:AD:DP 0/0:2,0:2 chr1 10543 . G A 47.93 . AC=2;AF=0.00122;AN=1640;DP=3590;ExcessHet=0.0374;FS=0;InbreedingCoeff=-0.0556;MLEAC=1;MLEAF=0.0006098;MQ=1.03;QD=15.98;SOR=2.833 GT:AD:DP:PL 0/0:2,0:2:0,6,90 chr1 10544 . A . . . AN=1570;DP=3548 GT:AD:DP 0/0:2:2 chr1 10545 . A . . . AN=1556;DP=3552 GT:AD:DP 0/0:2:2 chr1 10546 . A . . . AN=1536;DP=3509 GT:AD:DP 0/0:2:2 chr1 10547 . T . . . AN=1488;DP=3456 GT:AD:DP 0/0:2:2 chr1 10548 . C . . . AN=1622;DP=3500 GT:AD:DP 0/0:2:2 chr1 10549 . T . . . AN=1406;DP=3391 GT:AD:DP 0/0:2:2 chr1 10550 . G . . . AN=1606;DP=3429 GT:AD:DP 0/0:2:2 chr1 10551 . T . . . AN=1446;DP=3342 GT:AD:DP 0/0:2:2 chr1 10552 . G . . . AN=1606;DP=3357 GT:AD:DP 0/0:2:2 chr1 10553 . C . . . AN=1598;DP=3346 GT:AD:DP 0/0:2:2 chr1 10554 . A . . . AN=1496;DP=3290 GT:AD:DP 0/0:2:2 chr1 10555 . G . . . AN=1598;DP=3269 GT:AD:DP 0/0:2:2 chr1 10556 . A . . . AN=1504;DP=3232 GT:AD:DP 0/0:2:2 chr1 10557 . G . . . AN=1586;DP=3223 GT:AD:DP 0/0:2:2 chr1 10558 . G C . . AC=0;AF=0;AN=1574;DP=3196;ExcessHet=3.01;MQ=0.53 GT:AD:DP 0/0:2,0:2 chr1 10559 . A . . . AN=1466;DP=3127 GT:AD:DP 0/0:2:2 chr1 10560 . C . . . AN=1544;DP=3122 GT:AD:DP 0/0:2:2 chr1 10561 . A . . . AN=1516;DP=3092 GT:AD:DP 0/0:2:2 chr1 10562 . A . . . AN=1514;DP=3029 GT:AD:DP 0/0:2:2 chr1 10563 . C . . . AN=1560;DP=3005 GT:AD:DP 0/0:2:2 chr1 10564 . G . . . AN=1554;DP=2957 GT:AD:DP 0/0:2:2 chr1 10565 . C T . . AC=0;AF=0;AN=1542;BaseQRankSum=0.922;ClippingRankSum=-0.922;DP=2938;ExcessHet=3.01;MQ=1.07;MQRankSum=1.5;ReadPosRankSum=0.922 GT:AD:DP 0/0:2,0:2 chr1 10566 . A . . . AN=1482;DP=2887 GT:AD:DP 0/0:1:1 chr1 10567 . G . . . AN=1538;DP=2852 GT:AD:DP ./.:1:1 chr1 10568 . C . . . AN=1536;DP=2825 GT:AD:DP ./.:1:1 chr1 10569 . T . . . AN=1374;DP=2735 GT:AD:DP ./.:1:1 chr1 10570 . C A . . AC=0;AF=0;AN=1530;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=2756;ExcessHet=3.01;MQ=1.01;MQRankSum=-0.736;ReadPosRankSum=0.736 GT:AD:DP ./.:1,0:1 chr1 10571 . C . . . AN=1534;DP=2715 GT:AD:DP ./.:1:1 chr1 10572 . G . . . AN=1510;DP=2681 GT:AD:DP ./.:1:1 chr1 10573 . C . . . AN=1540;DP=2643 GT:AD:DP ./.:1:1 chr1 10574 . C . . . AN=1520;DP=2638 GT:AD:DP ./.:1:1 chr1 10575 . C . . . AN=1514;DP=2615 GT:AD:DP ./.:1:1 chr1 10576 . T . . . AN=1338;DP=2546 GT:AD:DP ./.:1:1 chr1 10577 . C . . . AN=1518;DP=2560 GT:AD:DP ./.:0:0 chr1 10578 . G . . . AN=1426;DP=2516 GT:AD:DP ./.:0:0 chr1 10579 . C . . . AN=1484;DP=2512 GT:AD:DP ./.:0:0 chr1 10580 . G . . . AN=1484;DP=2479 GT:AD:DP ./.:0:0 chr1 10581 . G . . . AN=1478;DP=2471 GT:AD:DP ./.:0:0 chr1 10582 . T . . . AN=1336;DP=2434 GT:AD:DP ./.:0:0 chr1 10583 . G . . . AN=1298;DP=2434 GT:AD:DP ./.:0:0 chr1 10584 . C . . . AN=1478;DP=2417 GT:AD:DP ./.:0:0 chr1 10585 . T . . . AN=1292;DP=2370 GT:AD:DP ./.:0:0 chr1 10586 . C . . . AN=1482;DP=2402 GT:AD:DP ./.:0:0 chr1 10587 . T . . . AN=1316;DP=2367 GT:AD:DP ./.:0:0 chr1 10588 . C . . . AN=1466;DP=2366 GT:AD:DP ./.:0:0 chr1 10589 . C . . . AN=1430;DP=2344 GT:AD:DP ./.:0:0 chr1 10590 . G . . . AN=1432;DP=2286 GT:AD:DP ./.:0:0 chr1 10591 . G . . . AN=1400;DP=2253 GT:AD:DP ./.:0:0 chr1 10592 . G . . . AN=1432;DP=2238 GT:AD:DP ./.:0:0 chr1 10593 . T . . . AN=1200;DP=2194 GT:AD:DP ./.:0:0 chr1 10594 . C . . . AN=1424;DP=2198 GT:AD:DP ./.:0:0 chr1 10595 . T . . . AN=1264;DP=2153 GT:AD:DP ./.:0:0 chr1 10596 . G . . . AN=1382;DP=2142 GT:AD:DP ./.:0:0 chr1 10597 . T . . . AN=1242;DP=2115 GT:AD:DP ./.:0:0 chr1 10598 . G . . . AN=1380;DP=2093 GT:AD:DP ./.:0:0 chr1 10599 . C . . . AN=1344;DP=2044 GT:AD:DP ./.:0:0 chr1 10600 . T . . . AN=1172;DP=2012 GT:AD:DP ./.:0:0 chr1 10601 . G . . . AN=1354;DP=2005 GT:AD:DP ./.:0:0 chr1 10602 . A . . . AN=1230;DP=1962 GT:AD:DP ./.:0:0 chr1 10603 . G . . . AN=1348;DP=1953 GT:AD:DP ./.:0:0 chr1 10604 . G . . . AN=1338;DP=1924 GT:AD:DP ./.:0:0 chr1 10605 . A . . . AN=1252;DP=1885 GT:AD:DP ./.:0:0 chr1 10606 . G . . . AN=1302;DP=1868 GT:AD:DP ./.:0:0 chr1 10607 . A . . . AN=1178;DP=1835 GT:AD:DP ./.:0:0 chr1 10608 . A . . . AN=1192;DP=1808 GT:AD:DP ./.:0:0 chr1 10609 . C . . . AN=1188;DP=1783 GT:AD:DP ./.:0:0 chr1 10610 . G . . . AN=1196;DP=1760 GT:AD:DP ./.:0:0 chr1 10611 . C G 1132.4 . AC=20;AF=0.045;AN=446;BaseQRankSum=0.742;ClippingRankSum=0.742;DP=1730;ExcessHet=0;FS=14.914;InbreedingCoeff=-0.0127;MLEAC=30;MLEAF=0.067;MQ=3.58;MQRankSum=0.742;QD=30.61;ReadPosRankSum=0.742;SOR=7.327 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 10612 . A . . . AN=950;DP=1714 GT:AD:DP ./.:0:0 chr1 10613 . A . . . AN=856;DP=1704 GT:AD:DP ./.:0:0 chr1 10614 . C . . . AN=878;DP=1689 GT:AD:DP ./.:0:0 chr1 10615 . T . . . AN=828;DP=1657 GT:AD:DP ./.:0:0 chr1 10616 . CCGCCGTTGCAAAGGCGCGCCG C 252.77 . AC=7;AF=0.007692;AN=910;BaseQRankSum=1.23;ClippingRankSum=0.358;DP=1618;ExcessHet=0;FS=13.222;InbreedingCoeff=-0.0961;MLEAC=6;MLEAF=0.006593;MQ=2.49;MQRankSum=-0.358;QD=19.44;ReadPosRankSum=-1.026;SOR=3.221 GT:AD:DP:PL ./.:0,0:0:. chr1 10617 . C . . . AN=892;DP=1592 GT:AD:DP ./.:0:0 chr1 10618 . G . . . AN=866;DP=1535 GT:AD:DP ./.:0:0 chr1 10619 . C . . . AN=866;DP=1504 GT:AD:DP ./.:0:0 chr1 10620 . C . . . AN=884;DP=1493 GT:AD:DP ./.:0:0 chr1 10621 . G . . . AN=878;DP=1445 GT:AD:DP ./.:0:0 chr1 10622 . T G 70.94 . AC=6;AF=0.007042;AN=852;DP=1408;ExcessHet=0.0004;FS=0;InbreedingCoeff=-0.1312;MLEAC=6;MLEAF=0.007042;MQ=1.45;QD=33.49;SOR=1.609 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 10623 . T C 1056.23 . AC=10;AF=0.161;AN=62;DP=1385;ExcessHet=0.0001;FS=0;InbreedingCoeff=0.2163;MLEAC=15;MLEAF=0.242;MQ=2.9;QD=33.07;SOR=4.255 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 10624 . G . . . AN=868;DP=1377 GT:AD:DP ./.:0:0 chr1 10625 . C . . . AN=846;DP=1378 GT:AD:DP ./.:0:0 chr1 10626 . A . . . AN=854;DP=1399 GT:AD:DP ./.:0:0 chr1 10627 . A . . . AN=562;DP=1463 GT:AD:DP ./.:0:0 chr1 10628 . A . . . AN=718;DP=1466 GT:AD:DP ./.:0:0 chr1 10629 . G . . . AN=796;DP=1562 GT:AD:DP ./.:0:0 chr1 10630 . G . . . AN=834;DP=1635 GT:AD:DP ./.:0:0 chr1 10631 . C . . . AN=762;DP=1686 GT:AD:DP ./.:0:0 chr1 10632 . G . . . AN=746;DP=1769 GT:AD:DP ./.:0:0 chr1 10633 . C . . . AN=982;DP=1875 GT:AD:DP ./.:0:0 chr1 10634 . G . . . AN=1042;DP=1978 GT:AD:DP ./.:0:0 chr1 10635 . C . . . AN=1094;DP=2055 GT:AD:DP ./.:0:0 chr1 10636 . C . . . AN=976;DP=2137 GT:AD:DP ./.:0:0 chr1 10637 . G . . . AN=1106;DP=2271 GT:AD:DP ./.:0:0 chr1 10638 . C . . . AN=1172;DP=2307 GT:AD:DP ./.:0:0 chr1 10639 . G . . . AN=942;DP=2412 GT:AD:DP ./.:0:0 chr1 10640 . C . . . AN=1080;DP=2475 GT:AD:DP ./.:0:0 chr1 10641 . C . . . AN=940;DP=2554 GT:AD:DP ./.:0:0 chr1 10642 . G . . . AN=1208;DP=2654 GT:AD:DP ./.:0:0 chr1 10643 . G . . . AN=1236;DP=2722 GT:AD:DP ./.:0:0 chr1 10644 . C . . . AN=1260;DP=2810 GT:AD:DP ./.:0:0 chr1 10645 . G . . . AN=1228;DP=2926 GT:AD:DP ./.:0:0 chr1 10646 . C . . . AN=1150;DP=3003 GT:AD:DP ./.:0:0 chr1 10647 . A . . . AN=1036;DP=2968 GT:AD:DP ./.:0:0 chr1 10648 . G . . . AN=1266;DP=3128 GT:AD:DP ./.:0:0 chr1 10649 . G . . . AN=1154;DP=3168 GT:AD:DP ./.:0:0 chr1 10650 . C . . . AN=1274;DP=3207 GT:AD:DP ./.:0:0 chr1 10651 . G . . . AN=1286;DP=3280 GT:AD:DP ./.:0:0 chr1 10652 . C . . . AN=1212;DP=3314 GT:AD:DP ./.:0:0 chr1 10653 . A . . . AN=1192;DP=3298 GT:AD:DP ./.:0:0 chr1 10654 . G . . . AN=1216;DP=3364 GT:AD:DP ./.:0:0 chr1 10655 . A . . . AN=1132;DP=3320 GT:AD:DP ./.:0:0 chr1 10656 . G . . . AN=1264;DP=3419 GT:AD:DP ./.:0:0 chr1 10657 . A . . . AN=1006;DP=3309 GT:AD:DP ./.:0:0 chr1 10658 . G . . . AN=1230;DP=3407 GT:AD:DP ./.:0:0 chr1 10659 . G . . . AN=1222;DP=3437 GT:AD:DP ./.:0:0 chr1 10660 . C . . . AN=1084;DP=3434 GT:AD:DP ./.:0:0 chr1 10661 . G . . . AN=1140;DP=3470 GT:AD:DP ./.:0:0 chr1 10662 . C . . . AN=1218;DP=3483 GT:AD:DP ./.:0:0 chr1 10663 . G . . . AN=1268;DP=3499 GT:AD:DP ./.:0:0 chr1 10664 . C . . . AN=1276;DP=3508 GT:AD:DP ./.:0:0 chr1 10665 . C . . . AN=1258;DP=3515 GT:AD:DP ./.:0:0 chr1 10666 . G . . . AN=1248;DP=3541 GT:AD:DP ./.:0:0 chr1 10667 . C . . . AN=1222;DP=3549 GT:AD:DP ./.:0:0 chr1 10668 . G . . . AN=1170;DP=3591 GT:AD:DP ./.:0:0 chr1 10669 . C . . . AN=1196;DP=3587 GT:AD:DP ./.:0:0 chr1 10670 . C . . . AN=1140;DP=3583 GT:AD:DP ./.:0:0 chr1 10671 . G . . . AN=1252;DP=3626 GT:AD:DP ./.:0:0 chr1 10672 . G . . . AN=1266;DP=3638 GT:AD:DP ./.:0:0 chr1 10673 . C . . . AN=1276;DP=3655 GT:AD:DP ./.:0:0 chr1 10674 . G . . . AN=1270;DP=3684 GT:AD:DP ./.:0:0 chr1 10675 . C . . . AN=1250;DP=3713 GT:AD:DP ./.:0:0 chr1 10676 . A . . . AN=972;DP=3609 GT:AD:DP ./.:0:0 chr1 10677 . G . . . AN=1268;DP=3759 GT:AD:DP ./.:0:0 chr1 10678 . G . . . AN=1128;DP=3762 GT:AD:DP ./.:0:0 chr1 10679 . C . . . AN=1258;DP=3745 GT:AD:DP ./.:0:0 chr1 10680 . G . . . AN=1276;DP=3807 GT:AD:DP ./.:0:0 chr1 10681 . C . . . AN=1248;DP=3811 GT:AD:DP ./.:0:0 chr1 10682 . A . . . AN=1144;DP=3723 GT:AD:DP ./.:0:0 chr1 10683 . G . . . AN=1244;DP=3852 GT:AD:DP ./.:0:0 chr1 10684 . A . . . AN=1160;DP=3713 GT:AD:DP ./.:0:0 chr1 10685 . G . . . AN=1244;DP=3855 GT:AD:DP ./.:0:0 chr1 10686 . A . . . AN=1002;DP=3661 GT:AD:DP ./.:0:0 chr1 10687 . G . . . AN=1166;DP=3821 GT:AD:DP ./.:0:0 chr1 10688 . G . . . AN=1232;DP=3881 GT:AD:DP ./.:0:0 chr1 10689 . C . . . AN=1150;DP=3877 GT:AD:DP ./.:0:0 chr1 10690 . G . . . AN=1240;DP=3897 GT:AD:DP ./.:0:0 chr1 10691 . C . . . AN=1188;DP=3906 GT:AD:DP ./.:0:0 chr1 10692 . G . . . AN=1268;DP=3928 GT:AD:DP ./.:0:0 chr1 10693 . C . . . AN=1262;DP=3913 GT:AD:DP ./.:0:0 chr1 10694 . C . . . AN=1236;DP=3928 GT:AD:DP ./.:0:0 chr1 10695 . G . . . AN=1264;DP=3944 GT:AD:DP ./.:0:0 chr1 10696 . C . . . AN=1178;DP=3943 GT:AD:DP ./.:0:0 chr1 10697 . G . . . AN=1234;DP=3968 GT:AD:DP ./.:0:0 chr1 10698 . C . . . AN=1224;DP=3970 GT:AD:DP ./.:0:0 chr1 10699 . C . . . AN=1264;DP=3974 GT:AD:DP ./.:0:0 chr1 10700 . G . . . AN=1284;DP=4002 GT:AD:DP ./.:0:0 chr1 10701 . G . . . AN=1288;DP=4030 GT:AD:DP ./.:0:0 chr1 10702 . C . . . AN=1284;DP=4030 GT:AD:DP ./.:0:0 chr1 10703 . G . . . AN=1296;DP=4065 GT:AD:DP ./.:0:0 chr1 10704 . C . . . AN=1254;DP=4051 GT:AD:DP ./.:0:0 chr1 10705 . A . . . AN=1074;DP=3952 GT:AD:DP ./.:0:0 chr1 10706 . G . . . AN=1300;DP=4068 GT:AD:DP ./.:0:0 chr1 10707 . G . . . AN=1282;DP=4078 GT:AD:DP ./.:0:0 chr1 10708 . C . . . AN=1286;DP=4084 GT:AD:DP ./.:0:0 chr1 10709 . G . . . AN=1312;DP=4102 GT:AD:DP ./.:0:0 chr1 10710 . C . . . AN=1300;DP=4097 GT:AD:DP ./.:0:0 chr1 10711 . A . . . AN=1142;DP=3993 GT:AD:DP ./.:0:0 chr1 10712 . G . . . AN=1312;DP=4101 GT:AD:DP ./.:0:0 chr1 10713 . A . . . AN=1178;DP=4004 GT:AD:DP ./.:0:0 chr1 10714 . G . . . AN=1324;DP=4102 GT:AD:DP ./.:0:0 chr1 10715 . A . . . AN=1062;DP=3960 GT:AD:DP ./.:0:0 chr1 10716 . G . . . AN=1126;DP=4027 GT:AD:DP ./.:0:0 chr1 10717 . G . . . AN=1312;DP=4081 GT:AD:DP ./.:0:0 chr1 10718 . C . . . AN=1290;DP=4072 GT:AD:DP ./.:0:0 chr1 10719 . G C . . AC=0;AF=0;AN=1228;BaseQRankSum=0.135;ClippingRankSum=0.38;DP=4032;ExcessHet=3.01;MQ=1.09;MQRankSum=0.135;ReadPosRankSum=-1 GT:AD:DP ./.:0,0:0 chr1 10720 . C . . . AN=1228;DP=4048 GT:AD:DP ./.:0:0 chr1 10721 . G . . . AN=1308;DP=4066 GT:AD:DP ./.:0:0 chr1 10722 . C . . . AN=1308;DP=4045 GT:AD:DP ./.:0:0 chr1 10723 . C . . . AN=1302;DP=4034 GT:AD:DP ./.:0:0 chr1 10724 . G . . . AN=1314;DP=4042 GT:AD:DP ./.:0:0 chr1 10725 . C . . . AN=1216;DP=4034 GT:AD:DP ./.:0:0 chr1 10726 . G . . . AN=1302;DP=4056 GT:AD:DP ./.:0:0 chr1 10727 . C . . . AN=1246;DP=4019 GT:AD:DP ./.:0:0 chr1 10728 . C . . . AN=1312;DP=4026 GT:AD:DP ./.:0:0 chr1 10729 . G . . . AN=1304;DP=4021 GT:AD:DP ./.:0:0 chr1 10730 . G . . . AN=1316;DP=4022 GT:AD:DP ./.:0:0 chr1 10731 . C . . . AN=1318;DP=4019 GT:AD:DP ./.:0:0 chr1 10732 . G . . . AN=1316;DP=4016 GT:AD:DP ./.:0:0 chr1 10733 . C . . . AN=1296;DP=3993 GT:AD:DP ./.:0:0 chr1 10734 . A . . . AN=1062;DP=3897 GT:AD:DP ./.:0:0 chr1 10735 . G . . . AN=1306;DP=3995 GT:AD:DP ./.:0:0 chr1 10736 . G . . . AN=1302;DP=4001 GT:AD:DP ./.:0:0 chr1 10737 . C . . . AN=1274;DP=3969 GT:AD:DP ./.:0:0 chr1 10738 . G . . . AN=1310;DP=3983 GT:AD:DP ./.:0:0 chr1 10739 . C . . . AN=1272;DP=3955 GT:AD:DP ./.:0:0 chr1 10740 . A . . . AN=1094;DP=3859 GT:AD:DP ./.:0:0 chr1 10741 . G . . . AN=1292;DP=3936 GT:AD:DP ./.:0:0 chr1 10742 . A . . . AN=1156;DP=3827 GT:AD:DP ./.:0:0 chr1 10743 . G . . . AN=1292;DP=3904 GT:AD:DP ./.:0:0 chr1 10744 . A . . . AN=1086;DP=3788 GT:AD:DP ./.:0:0 chr1 10745 . G . . . AN=954;DP=3834 GT:AD:DP ./.:0:0 chr1 10746 . G . . . AN=1260;DP=3879 GT:AD:DP ./.:0:0 chr1 10747 . C . . . AN=1260;DP=3867 GT:AD:DP ./.:0:0 chr1 10748 . G . . . AN=1260;DP=3867 GT:AD:DP ./.:0:0 chr1 10749 . C . . . AN=1192;DP=3873 GT:AD:DP ./.:0:0 chr1 10750 . G . . . AN=1296;DP=3851 GT:AD:DP ./.:0:0 chr1 10751 . C . . . AN=1280;DP=3839 GT:AD:DP ./.:0:0 chr1 10752 . C . . . AN=1266;DP=3848 GT:AD:DP ./.:0:0 chr1 10753 . G . . . AN=1280;DP=3841 GT:AD:DP ./.:0:0 chr1 10754 . C . . . AN=1172;DP=3840 GT:AD:DP ./.:0:0 chr1 10755 . G . . . AN=1290;DP=3860 GT:AD:DP ./.:0:0 chr1 10756 . C . . . AN=1210;DP=3826 GT:AD:DP ./.:0:0 chr1 10757 . C . . . AN=1300;DP=3842 GT:AD:DP ./.:0:0 chr1 10758 . G . . . AN=1306;DP=3853 GT:AD:DP ./.:0:0 chr1 10759 . G . . . AN=1298;DP=3876 GT:AD:DP ./.:0:0 chr1 10760 . C . . . AN=1284;DP=3842 GT:AD:DP ./.:0:0 chr1 10761 . G . . . AN=1302;DP=3849 GT:AD:DP ./.:0:0 chr1 10762 . C . . . AN=1282;DP=3823 GT:AD:DP ./.:0:0 chr1 10763 . A . . . AN=1062;DP=3711 GT:AD:DP ./.:0:0 chr1 10764 . G . . . AN=1274;DP=3837 GT:AD:DP ./.:0:0 chr1 10765 . G . . . AN=1262;DP=3850 GT:AD:DP ./.:0:0 chr1 10766 . C . . . AN=1258;DP=3823 GT:AD:DP ./.:0:0 chr1 10767 . G . . . AN=1278;DP=3840 GT:AD:DP ./.:0:0 chr1 10768 . C . . . AN=1238;DP=3809 GT:AD:DP ./.:0:0 chr1 10769 . A . . . AN=1124;DP=3724 GT:AD:DP ./.:0:0 chr1 10770 . G . . . AN=1274;DP=3832 GT:AD:DP ./.:0:0 chr1 10771 . A . . . AN=1120;DP=3695 GT:AD:DP ./.:0:0 chr1 10772 . G . . . AN=1218;DP=3828 GT:AD:DP ./.:0:0 chr1 10773 . A . . . AN=1054;DP=3638 GT:AD:DP ./.:0:0 chr1 10774 . G . . . AN=848;DP=3706 GT:AD:DP ./.:0:0 chr1 10775 . G . . . AN=1158;DP=3722 GT:AD:DP ./.:0:0 chr1 10776 . C . . . AN=1146;DP=3667 GT:AD:DP ./.:0:0 chr1 10777 . G . . . AN=1158;DP=3617 GT:AD:DP ./.:0:0 chr1 10778 . C . . . AN=1132;DP=3562 GT:AD:DP ./.:0:0 chr1 10779 . G . . . AN=1144;DP=3458 GT:AD:DP ./.:0:0 chr1 10780 . C . . . AN=1102;DP=3365 GT:AD:DP ./.:0:0 chr1 10781 . C . . . AN=1066;DP=3315 GT:AD:DP ./.:0:0 chr1 10782 . G . . . AN=1042;DP=3219 GT:AD:DP ./.:0:0 chr1 10783 . C G . . AC=0;AF=0;AN=934;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=3129;ExcessHet=3.01;MQ=0.51;MQRankSum=0.804;ReadPosRankSum=0.804 GT:AD:DP ./.:0,0:0 chr1 10784 . G . . . AN=968;DP=3028 GT:AD:DP ./.:0:0 chr1 10785 . C . . . AN=940;DP=2915 GT:AD:DP ./.:0:0 chr1 10786 . C . . . AN=950;DP=2893 GT:AD:DP ./.:0:0 chr1 10787 . G . . . AN=928;DP=2800 GT:AD:DP ./.:0:0 chr1 10788 . G . . . AN=908;DP=2737 GT:AD:DP ./.:0:0 chr1 10789 . C . . . AN=922;DP=2671 GT:AD:DP ./.:0:0 chr1 10790 . G . . . AN=928;DP=2578 GT:AD:DP ./.:0:0 chr1 10791 . C . . . AN=890;DP=2487 GT:AD:DP ./.:0:0 chr1 10792 . A . . . AN=708;DP=2336 GT:AD:DP ./.:0:0 chr1 10793 . G . . . AN=890;DP=2386 GT:AD:DP ./.:0:0 chr1 10794 . G . . . AN=870;DP=2339 GT:AD:DP ./.:0:0 chr1 10795 . C . . . AN=826;DP=2213 GT:AD:DP ./.:0:0 chr1 10796 . G . . . AN=820;DP=2141 GT:AD:DP ./.:0:0 chr1 10797 . C . . . AN=794;DP=2045 GT:AD:DP ./.:0:0 chr1 10798 . A . . . AN=686;DP=1923 GT:AD:DP ./.:0:0 chr1 10799 . G . . . AN=784;DP=1955 GT:AD:DP ./.:0:0 chr1 10800 . A . . . AN=660;DP=1868 GT:AD:DP ./.:0:0 chr1 10801 . C . . . AN=656;DP=1826 GT:AD:DP ./.:0:0 chr1 10802 . A . . . AN=654;DP=1824 GT:AD:DP ./.:0:0 chr1 10803 . C . . . AN=642;DP=1807 GT:AD:DP ./.:0:0 chr1 10804 . A . . . AN=524;DP=1760 GT:AD:DP ./.:0:0 chr1 10805 . T . . . AN=412;DP=1747 GT:AD:DP ./.:0:0 chr1 10806 . G . . . AN=470;DP=1767 GT:AD:DP ./.:0:0 chr1 10807 . C . . . AN=438;DP=1746 GT:AD:DP ./.:0:0 chr1 10808 . T . . . AN=338;DP=1719 GT:AD:DP ./.:0:0 chr1 10809 . A . . . AN=246;DP=1729 GT:AD:DP ./.:0:0 chr1 10810 . G . . . AN=282;DP=1746 GT:AD:DP ./.:0:0 chr1 10811 . C . . . AN=280;DP=1735 GT:AD:DP ./.:0:0 chr1 10812 . G . . . AN=280;DP=1740 GT:AD:DP ./.:0:0 chr1 10813 . C . . . AN=246;DP=1727 GT:AD:DP ./.:0:0 chr1 10814 . G . . . AN=270;DP=1713 GT:AD:DP ./.:0:0 chr1 10815 . T . . . AN=120;DP=1669 GT:AD:DP ./.:0:0 chr1 10816 . C CCA 334.85 . AC=7;AF=0.022;AN=324;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=1688;ExcessHet=0.001;FS=0;InbreedingCoeff=-0.0721;MLEAC=10;MLEAF=0.031;MQ=1.71;MQRankSum=-0.736;QD=30.44;ReadPosRankSum=-0.736;SOR=0.399 GT:AD:DP:PL ./.:0,0:0:. chr1 10817 . G . . . AN=532;DP=1696 GT:AD:DP ./.:0:0 chr1 10818 . G . . . AN=930;DP=1687 GT:AD:DP ./.:0:0 chr1 10819 . G T . . AC=0;AF=0;AN=970;BaseQRankSum=-0.736;ClippingRankSum=0.736;DP=1672;ExcessHet=3.01;MQ=1.09;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP ./.:0,0:0 chr1 10820 . G . . . AN=986;DP=1652 GT:AD:DP ./.:0:0 chr1 10821 . T . . . AN=576;DP=1580 GT:AD:DP ./.:0:0 chr1 10822 . G . . . AN=974;DP=1612 GT:AD:DP ./.:0:0 chr1 10823 . G . . . AN=944;DP=1601 GT:AD:DP ./.:0:0 chr1 10824 . A . . . AN=658;DP=1561 GT:AD:DP ./.:0:0 chr1 10825 . G . . . AN=966;DP=1562 GT:AD:DP ./.:0:0 chr1 10826 . G . . . AN=922;DP=1553 GT:AD:DP ./.:0:0 chr1 10827 . C . . . AN=904;DP=1521 GT:AD:DP ./.:0:0 chr1 10828 . G . . . AN=940;DP=1519 GT:AD:DP ./.:0:0 chr1 10829 . T . . . AN=608;DP=1487 GT:AD:DP ./.:0:0 chr1 10830 . G . . . AN=950;DP=1517 GT:AD:DP ./.:0:0 chr1 10831 . G . . . AN=948;DP=1506 GT:AD:DP ./.:0:0 chr1 10832 . C . . . AN=932;DP=1473 GT:AD:DP ./.:0:0 chr1 10833 . G . . . AN=962;DP=1467 GT:AD:DP ./.:0:0 chr1 10834 . C . . . AN=930;DP=1456 GT:AD:DP ./.:0:0 chr1 10835 . A . . . AN=708;DP=1432 GT:AD:DP ./.:0:0 chr1 10836 . G . . . AN=908;DP=1441 GT:AD:DP ./.:0:0 chr1 10837 . G . . . AN=898;DP=1442 GT:AD:DP ./.:0:0 chr1 10838 . C . . . AN=872;DP=1427 GT:AD:DP ./.:0:0 chr1 10839 . G . . . AN=920;DP=1430 GT:AD:DP ./.:0:0 chr1 10840 . C . . . AN=884;DP=1404 GT:AD:DP ./.:0:0 chr1 10841 . A . . . AN=772;DP=1375 GT:AD:DP ./.:0:0 chr1 10842 . G . . . AN=908;DP=1387 GT:AD:DP ./.:0:0 chr1 10843 . A . . . AN=756;DP=1363 GT:AD:DP ./.:0:0 chr1 10844 . G . . . AN=892;DP=1365 GT:AD:DP ./.:0:0 chr1 10845 . A . . . AN=692;DP=1347 GT:AD:DP ./.:0:0 chr1 10846 . G . . . AN=888;DP=1342 GT:AD:DP ./.:0:0 chr1 10847 . G . . . AN=898;DP=1326 GT:AD:DP ./.:0:0 chr1 10848 . C . . . AN=848;DP=1301 GT:AD:DP ./.:0:0 chr1 10849 . G . . . AN=894;DP=1282 GT:AD:DP ./.:0:0 chr1 10850 . C . . . AN=894;DP=1261 GT:AD:DP ./.:0:0 chr1 10851 . G . . . AN=898;DP=1242 GT:AD:DP ./.:0:0 chr1 10852 . C . . . AN=888;DP=1209 GT:AD:DP ./.:0:0 chr1 10853 . C . . . AN=868;DP=1194 GT:AD:DP ./.:0:0 chr1 10854 . G . . . AN=922;DP=1180 GT:AD:DP ./.:0:0 chr1 10855 . C . . . AN=894;DP=1188 GT:AD:DP ./.:0:0 chr1 10856 . G . . . AN=904;DP=1192 GT:AD:DP ./.:0:0 chr1 10857 . C . . . AN=836;DP=1192 GT:AD:DP ./.:0:0 chr1 10858 . C . . . AN=886;DP=1198 GT:AD:DP ./.:0:0 chr1 10859 . G . . . AN=908;DP=1202 GT:AD:DP ./.:0:0 chr1 10860 . G . . . AN=914;DP=1220 GT:AD:DP ./.:0:0 chr1 10861 . C . . . AN=906;DP=1228 GT:AD:DP ./.:0:0 chr1 10862 . G . . . AN=940;DP=1242 GT:AD:DP ./.:0:0 chr1 10863 . C . . . AN=902;DP=1245 GT:AD:DP ./.:0:0 chr1 10864 . A . . . AN=734;DP=1234 GT:AD:DP ./.:0:0 chr1 10865 . G . . . AN=932;DP=1254 GT:AD:DP ./.:0:0 chr1 10866 . G . . . AN=922;DP=1254 GT:AD:DP ./.:0:0 chr1 10867 . C . . . AN=846;DP=1251 GT:AD:DP ./.:0:0 chr1 10868 . G . . . AN=936;DP=1262 GT:AD:DP ./.:0:0 chr1 10869 . C . . . AN=842;DP=1264 GT:AD:DP ./.:0:0 chr1 10870 . A . . . AN=748;DP=1264 GT:AD:DP ./.:0:0 chr1 10871 . G . . . AN=942;DP=1277 GT:AD:DP ./.:0:0 chr1 10872 . A . . . AN=752;DP=1280 GT:AD:DP ./.:0:0 chr1 10873 . G . . . AN=926;DP=1295 GT:AD:DP ./.:0:0 chr1 10874 . A . . . AN=724;DP=1296 GT:AD:DP ./.:0:0 chr1 10875 . C . . . AN=944;DP=1299 GT:AD:DP ./.:0:0 chr1 10876 . A . . . AN=724;DP=1299 GT:AD:DP ./.:0:0 chr1 10877 . C . . . AN=902;DP=1295 GT:AD:DP ./.:0:0 chr1 10878 . A . . . AN=718;DP=1296 GT:AD:DP ./.:0:0 chr1 10879 . T . . . AN=704;DP=1296 GT:AD:DP ./.:0:0 chr1 10880 . G . . . AN=974;DP=1311 GT:AD:DP ./.:0:0 chr1 10881 . C . . . AN=944;DP=1303 GT:AD:DP ./.:0:0 chr1 10882 . T . . . AN=662;DP=1303 GT:AD:DP ./.:0:0 chr1 10883 . A . . . AN=590;DP=1298 GT:AD:DP ./.:0:0 chr1 10884 . C . . . AN=880;DP=1307 GT:AD:DP ./.:0:0 chr1 10885 . C . . . AN=906;DP=1317 GT:AD:DP ./.:0:0 chr1 10886 . G . . . AN=956;DP=1321 GT:AD:DP ./.:0:0 chr1 10887 . C . . . AN=958;DP=1311 GT:AD:DP ./.:0:0 chr1 10888 . G . . . AN=948;DP=1314 GT:AD:DP ./.:0:0 chr1 10889 . T . . . AN=534;DP=1305 GT:AD:DP ./.:0:0 chr1 10890 . C . . . AN=962;DP=1319 GT:AD:DP ./.:0:0 chr1 10891 . C . . . AN=876;DP=1325 GT:AD:DP ./.:0:0 chr1 10892 . A . . . AN=826;DP=1329 GT:AD:DP ./.:0:0 chr1 10893 . G . . . AN=988;DP=1335 GT:AD:DP ./.:0:0 chr1 10894 . G . . . AN=998;DP=1338 GT:AD:DP ./.:0:0 chr1 10895 . G . . . AN=966;DP=1341 GT:AD:DP ./.:0:0 chr1 10896 . G . . . AN=992;DP=1348 GT:AD:DP ./.:0:0 chr1 10897 . T . . . AN=678;DP=1342 GT:AD:DP ./.:0:0 chr1 10898 . G . . . AN=1012;DP=1378 GT:AD:DP ./.:0:0 chr1 10899 . G . . . AN=964;DP=1374 GT:AD:DP ./.:0:0 chr1 10900 . A . . . AN=680;DP=1375 GT:AD:DP ./.:0:0 chr1 10901 . G . . . AN=1016;DP=1403 GT:AD:DP ./.:0:0 chr1 10902 . G . . . AN=944;DP=1414 GT:AD:DP ./.:0:0 chr1 10903 . C . . . AN=920;DP=1409 GT:AD:DP ./.:0:0 chr1 10904 . G A 265.79 . AC=3;AF=0.003464;AN=866;BaseQRankSum=0.762;ClippingRankSum=-0.762;DP=1424;ExcessHet=0.113;FS=0;InbreedingCoeff=-0.1149;MLEAC=3;MLEAF=0.003464;MQ=1.88;MQRankSum=0.067;QD=22.15;ReadPosRankSum=1.18;SOR=2.67 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 10905 . T . . . AN=582;DP=1425 GT:AD:DP ./.:0:0 chr1 10906 . G . . . AN=1008;DP=1456 GT:AD:DP ./.:0:0 chr1 10907 . G . . . AN=1004;DP=1464 GT:AD:DP ./.:0:0 chr1 10908 . C . . . AN=1008;DP=1454 GT:AD:DP ./.:0:0 chr1 10909 . G . . . AN=1036;DP=1470 GT:AD:DP ./.:0:0 chr1 10910 . C . . . AN=1002;DP=1472 GT:AD:DP ./.:0:0 chr1 10911 . A . . . AN=794;DP=1478 GT:AD:DP ./.:0:0 chr1 10912 . G . . . AN=1020;DP=1498 GT:AD:DP ./.:0:0 chr1 10913 . G . . . AN=1018;DP=1502 GT:AD:DP ./.:0:0 chr1 10914 . C . . . AN=956;DP=1503 GT:AD:DP ./.:0:0 chr1 10915 . G . . . AN=1056;DP=1513 GT:AD:DP ./.:0:0 chr1 10916 . C . . . AN=1008;DP=1515 GT:AD:DP ./.:0:0 chr1 10917 . A . . . AN=838;DP=1525 GT:AD:DP ./.:0:0 chr1 10918 . G . . . AN=1054;DP=1553 GT:AD:DP ./.:0:0 chr1 10919 . A . . . AN=882;DP=1550 GT:AD:DP ./.:0:0 chr1 10920 . G . . . AN=1060;DP=1563 GT:AD:DP ./.:0:0 chr1 10921 . A . . . AN=774;DP=1559 GT:AD:DP ./.:0:0 chr1 10922 . G . . . AN=1036;DP=1565 GT:AD:DP ./.:0:0 chr1 10923 . G . . . AN=1038;DP=1564 GT:AD:DP ./.:0:0 chr1 10924 . C . . . AN=960;DP=1555 GT:AD:DP ./.:0:0 chr1 10925 . G . . . AN=1046;DP=1544 GT:AD:DP ./.:0:0 chr1 10926 . C . . . AN=1022;DP=1536 GT:AD:DP ./.:0:0 chr1 10927 . A G 344.47 . AC=2;AF=0.004717;AN=424;BaseQRankSum=2.02;ClippingRankSum=0.742;DP=1523;ExcessHet=3.0697;FS=0;InbreedingCoeff=-0.1703;MLEAC=6;MLEAF=0.014;MQ=2.05;MQRankSum=0.922;QD=22.96;ReadPosRankSum=0.742;SOR=1.473 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 10928 . C . . . AN=1012;DP=1531 GT:AD:DP ./.:0:0 chr1 10929 . C . . . AN=954;DP=1525 GT:AD:DP ./.:0:0 chr1 10930 . G . . . AN=1018;DP=1522 GT:AD:DP ./.:0:0 chr1 10931 . C . . . AN=1006;DP=1511 GT:AD:DP ./.:0:0 chr1 10932 . G . . . AN=1014;DP=1499 GT:AD:DP ./.:0:0 chr1 10933 . C . . . AN=1000;DP=1494 GT:AD:DP ./.:0:0 chr1 10934 . C . . . AN=922;DP=1490 GT:AD:DP ./.:0:0 chr1 10935 . G . . . AN=1010;DP=1477 GT:AD:DP ./.:0:0 chr1 10936 . G . . . AN=1020;DP=1463 GT:AD:DP ./.:0:0 chr1 10937 . C . . . AN=986;DP=1450 GT:AD:DP ./.:0:0 chr1 10938 . G A 111.03 . AC=1;AF=0.0009804;AN=1020;BaseQRankSum=0;ClippingRankSum=0.421;DP=1433;ExcessHet=3.0103;FS=0;InbreedingCoeff=-0.103;MLEAC=1;MLEAF=0.0009804;MQ=1.58;MQRankSum=-1.368;QD=13.88;ReadPosRankSum=-0.421;SOR=0.693 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 10939 . C . . . AN=1006;DP=1429 GT:AD:DP ./.:0:0 chr1 10940 . A . . . AN=794;DP=1414 GT:AD:DP ./.:0:0 chr1 10941 . G . . . AN=1022;DP=1411 GT:AD:DP ./.:0:0 chr1 10942 . G . . . AN=1002;DP=1405 GT:AD:DP ./.:0:0 chr1 10943 . C . . . AN=916;DP=1387 GT:AD:DP ./.:0:0 chr1 10944 . G . . . AN=1030;DP=1380 GT:AD:DP ./.:0:0 chr1 10945 . C . . . AN=974;DP=1371 GT:AD:DP ./.:0:0 chr1 10946 . A . . . AN=908;DP=1369 GT:AD:DP ./.:0:0 chr1 10947 . G . . . AN=1012;DP=1361 GT:AD:DP ./.:0:0 chr1 10948 . A . . . AN=932;DP=1358 GT:AD:DP ./.:0:0 chr1 10949 . G C . . AC=0;AF=0;AN=1004;BaseQRankSum=0.406;ClippingRankSum=0.406;DP=1353;ExcessHet=3.01;MQ=1.33;MQRankSum=-0.988;ReadPosRankSum=0.406 GT:AD:DP ./.:0,0:0 chr1 10950 . A . . . AN=908;DP=1347 GT:AD:DP ./.:0:0 chr1 10951 . C . . . AN=1006;DP=1339 GT:AD:DP ./.:0:0 chr1 10952 . A . . . AN=918;DP=1331 GT:AD:DP ./.:0:0 chr1 10953 . C . . . AN=998;DP=1323 GT:AD:DP ./.:0:0 chr1 10954 . A . . . AN=910;DP=1321 GT:AD:DP ./.:0:0 chr1 10955 . T . . . AN=866;DP=1318 GT:AD:DP ./.:0:0 chr1 10956 . G . . . AN=984;DP=1311 GT:AD:DP ./.:0:0 chr1 10957 . C . . . AN=988;DP=1304 GT:AD:DP ./.:0:0 chr1 10958 . T . . . AN=896;DP=1299 GT:AD:DP ./.:0:0 chr1 10959 . A . . . AN=842;DP=1292 GT:AD:DP ./.:0:0 chr1 10960 . G . . . AN=950;DP=1278 GT:AD:DP ./.:0:0 chr1 10961 . C . . . AN=984;DP=1266 GT:AD:DP ./.:0:0 chr1 10962 . G . . . AN=976;DP=1248 GT:AD:DP ./.:0:0 chr1 10963 . C . . . AN=976;DP=1237 GT:AD:DP ./.:0:0 chr1 10964 . G . . . AN=962;DP=1226 GT:AD:DP ./.:0:0 chr1 10965 . T . . . AN=732;DP=1221 GT:AD:DP ./.:0:0 chr1 10966 . C . . . AN=970;DP=1217 GT:AD:DP ./.:0:0 chr1 10967 . C . . . AN=936;DP=1208 GT:AD:DP ./.:0:0 chr1 10968 . A . . . AN=838;DP=1206 GT:AD:DP ./.:0:0 chr1 10969 . G . . . AN=962;DP=1199 GT:AD:DP ./.:0:0 chr1 10970 . G . . . AN=958;DP=1191 GT:AD:DP ./.:0:0 chr1 10971 . G . . . AN=946;DP=1187 GT:AD:DP ./.:0:0 chr1 10972 . G . . . AN=936;DP=1180 GT:AD:DP ./.:0:0 chr1 10973 . T . . . AN=800;DP=1165 GT:AD:DP ./.:0:0 chr1 10974 . G . . . AN=946;DP=1160 GT:AD:DP ./.:0:0 chr1 10975 . G . . . AN=924;DP=1152 GT:AD:DP ./.:0:0 chr1 10976 . A . . . AN=820;DP=1143 GT:AD:DP ./.:0:0 chr1 10977 . G . . . AN=944;DP=1132 GT:AD:DP ./.:0:0 chr1 10978 . G T . . AC=0;AF=0;AN=928;BaseQRankSum=1.03;ClippingRankSum=1.03;DP=1114;ExcessHet=3.01;MQ=1.2;MQRankSum=0;ReadPosRankSum=0 GT:AD:DP ./.:0,0:0 chr1 10979 . C . . . AN=892;DP=1108 GT:AD:DP ./.:0:0 chr1 10980 . G . . . AN=920;DP=1086 GT:AD:DP ./.:0:0 chr1 10981 . T . . . AN=676;DP=1078 GT:AD:DP ./.:0:0 chr1 10982 . G . . . AN=914;DP=1072 GT:AD:DP ./.:0:0 chr1 10983 . G . . . AN=916;DP=1069 GT:AD:DP ./.:0:0 chr1 10984 . C . . . AN=916;DP=1063 GT:AD:DP ./.:0:0 chr1 10985 . G . . . AN=918;DP=1047 GT:AD:DP ./.:0:0 chr1 10986 . C . . . AN=904;DP=1040 GT:AD:DP ./.:0:0 chr1 10987 . A . . . AN=858;DP=1038 GT:AD:DP ./.:0:0 chr1 10988 . G . . . AN=902;DP=1028 GT:AD:DP ./.:0:0 chr1 10989 . G . . . AN=892;DP=1018 GT:AD:DP ./.:0:0 chr1 10990 . C G 44.76 . AC=5;AF=0.006143;AN=814;BaseQRankSum=1.03;ClippingRankSum=0;DP=999;ExcessHet=0.0014;FS=0;InbreedingCoeff=-0.1212;MLEAC=4;MLEAF=0.004914;MQ=1.9;MQRankSum=-1.026;QD=6.39;ReadPosRankSum=1.03;SOR=1.402 GT:AD:DP:PL ./.:0,0:0:. chr1 10991 . G . . . AN=890;DP=992 GT:AD:DP ./.:0:0 chr1 10992 . C . . . AN=886;DP=985 GT:AD:DP ./.:0:0 chr1 10993 . A . . . AN=864;DP=978 GT:AD:DP ./.:0:0 chr1 10994 . G C . . AC=0;AF=0;AN=890;DP=969;ExcessHet=3.01;MQ=0.95 GT:AD:DP:PGT:PID ./.:0,0:0:.:. chr1 10995 . A . . . AN=846;DP=966 GT:AD:DP ./.:0:0 chr1 10996 . G . . . AN=882;DP=961 GT:AD:DP ./.:0:0 chr1 10997 . A . . . AN=812;DP=956 GT:AD:DP ./.:0:0 chr1 10998 . C . . . AN=836;DP=948 GT:AD:DP ./.:0:0 chr1 10999 . G . . . AN=854;DP=941 GT:AD:DP ./.:0:0 chr1 11000 . C . . . AN=838;DP=938 GT:AD:DP ./.:0:0 chr1 11001 . A . . . AN=830;DP=932 GT:AD:DP ./.:0:0 chr1 11002 . A . . . AN=796;DP=926 GT:AD:DP ./.:0:0 chr1 11003 . G . . . AN=800;DP=923 GT:AD:DP ./.:0:0 chr1 11004 . C . . . AN=804;DP=915 GT:AD:DP ./.:0:0 chr1 11005 . C . . . AN=794;DP=909 GT:AD:DP ./.:0:0 chr1 11006 . T . . . AN=772;DP=903 GT:AD:DP ./.:0:0 chr1 11007 . A . . . AN=768;DP=891 GT:AD:DP ./.:0:0 chr1 11008 . C . . . AN=780;DP=876 GT:AD:DP ./.:0:0 chr1 11009 . G . . . AN=792;DP=862 GT:AD:DP ./.:0:0 chr1 11010 . G . . . AN=776;DP=855 GT:AD:DP ./.:0:0 chr1 11011 . G C . . AC=0;AF=0;AN=774;DP=835;ExcessHet=3.01;MQ=0.73 GT:AD:DP:PGT:PID ./.:0,0:0:.:. chr1 11012 . C . . . AN=748;DP=816 GT:AD:DP ./.:0:0 chr1 11013 . G . . . AN=736;DP=798 GT:AD:DP ./.:0:0 chr1 11014 . G A 71.59 . AC=1;AF=0.001397;AN=716;BaseQRankSum=0;ClippingRankSum=0;DP=787;ExcessHet=3.0468;FS=0;InbreedingCoeff=-0.1474;MLEAC=1;MLEAF=0.001397;MQ=1.89;MQRankSum=0.55;QD=10.23;ReadPosRankSum=0.55;SOR=0.495 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 11015 . G . . . AN=738;DP=787 GT:AD:DP ./.:0:0 chr1 11016 . G . . . AN=742;DP=775 GT:AD:DP ./.:0:0 chr1 11017 . G . . . AN=738;DP=765 GT:AD:DP ./.:0:0 chr1 11018 . T . . . AN=720;DP=758 GT:AD:DP ./.:0:0 chr1 11019 . T . . . AN=664;DP=744 GT:AD:DP ./.:0:0 chr1 11020 . G . . . AN=722;DP=741 GT:AD:DP ./.:0:0 chr1 11021 . G . . . AN=718;DP=731 GT:AD:DP ./.:0:0 chr1 11022 . G A 99.81 . AC=3;AF=0.004505;AN=666;BaseQRankSum=0.988;ClippingRankSum=0.406;DP=719;ExcessHet=0.0198;FS=0;InbreedingCoeff=-0.1279;MLEAC=3;MLEAF=0.004505;MQ=2.14;MQRankSum=0.406;QD=12.48;ReadPosRankSum=0.406;SOR=1.179 GT:AD:DP:PGT:PID:PL ./.:0,0:0:.:.:. chr1 11023 . G . . . AN=706;DP=708 GT:AD:DP ./.:0:0 chr1 11024 . G . . . AN=702;DP=699 GT:AD:DP ./.:0:0 chr1 11025 . G . . . AN=706;DP=689 GT:AD:DP ./.:0:0 chr1 11026 . G . . . AN=690;DP=679 GT:AD:DP ./.:0:0 chr1 11027 . C . . . AN=672;DP=672 GT:AD:DP ./.:0:0 chr1 11028 . G . . . AN=690;DP=668 GT:AD:DP ./.:0:0 chr1 11029 . T . . . AN=656;DP=659 GT:AD:DP ./.:0:0 chr1 11030 . G . . . AN=678;DP=651 GT:AD:DP ./.:0:0 chr1 11031 . T . . . AN=652;DP=646 GT:AD:DP ./.:0:0 chr1 11032 . G . . . AN=674;DP=640 GT:AD:DP ./.:0:0 chr1 11033 . T . . . AN=632;DP=630 GT:AD:DP ./.:0:0 chr1 11034 . T . . . AN=614;DP=625 GT:AD:DP ./.:0:0 chr1 11035 . G . . . AN=646;DP=621 GT:AD:DP ./.:0:0 chr1 11036 . C . . . AN=612;DP=612 GT:AD:DP ./.:0:0 chr1 11037 . A . . . AN=582;DP=601 GT:AD:DP ./.:0:0 chr1 11038 . G . . . AN=610;DP=597 GT:AD:DP ./.:0:0 chr1 11039 . G . . . AN=576;DP=593 GT:AD:DP ./.:0:0 chr1 11040 . A . . . AN=538;DP=580 GT:AD:DP ./.:0:0 chr1 11041 . G . . . AN=534;DP=580 GT:AD:DP ./.:0:0 chr1 11042 . C . . . AN=496;DP=570 GT:AD:DP ./.:0:0 chr1 11043 . A . . . AN=494;DP=561 GT:AD:DP ./.:0:0 chr1 11044 . A . . . AN=466;DP=558 GT:AD:DP ./.:0:0 chr1 11045 . A . . . AN=412;DP=551 GT:AD:DP ./.:0:0 chr1 11046 . G . . . AN=418;DP=536 GT:AD:DP ./.:0:0 chr1 11047 . T . . . AN=362;DP=520 GT:AD:DP ./.:0:0 chr1 11048 . C . . . AN=348;DP=501 GT:AD:DP ./.:0:0 chr1 11049 . G . . . AN=360;DP=472 GT:AD:DP ./.:0:0 chr1 11050 . C . . . AN=340;DP=464 GT:AD:DP ./.:0:0 chr1 11051 . A . . . AN=288;DP=452 GT:AD:DP ./.:0:0 chr1 11052 . C . . . AN=276;DP=435 GT:AD:DP ./.:0:0 chr1 11053 . G . . . AN=340;DP=416 GT:AD:DP ./.:0:0 chr1 11054 . G . . . AN=300;DP=398 GT:AD:DP ./.:0:0 chr1 11055 . C . . . AN=266;DP=381 GT:AD:DP ./.:0:0 chr1 11056 . G . . . AN=262;DP=359 GT:AD:DP ./.:0:0 chr1 11057 . C . . . AN=214;DP=341 GT:AD:DP ./.:0:0 chr1 11058 . C . . . AN=72;DP=330 GT:AD:DP ./.:0:0 chr1 11059 . G . . . AN=182;DP=321 GT:AD:DP ./.:0:0 chr1 11060 . G . . . AN=198;DP=311 GT:AD:DP ./.:0:0 chr1 11061 . G . . . AN=202;DP=296 GT:AD:DP ./.:0:0 chr1 11062 . C . . . AN=86;DP=284 GT:AD:DP ./.:0:0 chr1 11063 . T . . . AN=32;DP=282 GT:AD:DP ./.:0:0 chr1 11064 . G . . . AN=216;DP=279 GT:AD:DP ./.:0:0 chr1 11065 . G . . . AN=212;DP=270 GT:AD:DP ./.:0:0 chr1 11066 . G . . . AN=230;DP=267 GT:AD:DP ./.:0:0 chr1 11067 . G . . . AN=240;DP=253 GT:AD:DP ./.:0:0 chr1 11068 . C . . . AN=74;DP=242 GT:AD:DP ./.:0:0 chr1 11069 . G . . . AN=254;DP=224 GT:AD:DP ./.:0:0 chr1 11070 . G . . . AN=264;DP=217 GT:AD:DP ./.:0:0 chr1 11071 . G . . . AN=256;DP=212 GT:AD:DP ./.:0:0 chr1 11072 . G . . . AN=270;DP=202 GT:AD:DP ./.:0:0 chr1 11073 . G . . . AN=266;DP=197 GT:AD:DP ./.:0:0 chr1 11074 . G . . . AN=266;DP=195 GT:AD:DP ./.:0:0 chr1 11075 . A . . . AN=38;DP=193 GT:AD:DP ./.:0:0 chr1 11076 . G . . . AN=286;DP=197 GT:AD:DP ./.:0:0 chr1 11077 . G . . . AN=306;DP=200 GT:AD:DP ./.:0:0 chr1 11078 . G . . . AN=302;DP=197 GT:AD:DP ./.:0:0 chr1 11079 . T . . . AN=132;DP=193 GT:AD:DP ./.:0:0 chr1 11080 . G . . . AN=300;DP=201 GT:AD:DP ./.:0:0 chr1 11081 . G . . . AN=254;DP=203 GT:AD:DP ./.:0:0 chr1 11082 . C . . . AN=300;DP=204 GT:AD:DP ./.:0:0 chr1 11083 . G . . . AN=318;DP=208 GT:AD:DP ./.:0:0 chr1 11084 . C . . . AN=332;DP=213 GT:AD:DP ./.:0:0 chr1 11085 . C . . . AN=316;DP=217 GT:AD:DP ./.:0:0 chr1 11086 . G . . . AN=330;DP=222 GT:AD:DP ./.:0:0 chr1 11087 . T . . . AN=260;DP=225 GT:AD:DP ./.:0:0 chr1 11088 . G . . . AN=350;DP=231 GT:AD:DP ./.:0:0 chr1 11089 . C . . . AN=352;DP=234 GT:AD:DP ./.:0:0 chr1 11090 . A . . . AN=272;DP=235 GT:AD:DP ./.:0:0 chr1 11091 . C . . . AN=352;DP=238 GT:AD:DP ./.:0:0 chr1 11092 . G . . . AN=364;DP=243 GT:AD:DP ./.:0:0 chr1 11093 . C . . . AN=358;DP=244 GT:AD:DP ./.:0:0 chr1 11094 . G . . . AN=372;DP=251 GT:AD:DP ./.:0:0 chr1 11095 . C . . . AN=364;DP=251 GT:AD:DP ./.:0:0 chr1 11096 . A . . . AN=294;DP=251 GT:AD:DP ./.:0:0 chr1 11097 . G . . . AN=392;DP=259 GT:AD:DP ./.:0:0 chr1 11098 . A . . . AN=304;DP=261 GT:AD:DP ./.:0:0 chr1 11099 . A . . . AN=276;DP=262 GT:AD:DP ./.:0:0 chr1 11100 . A . . . AN=218;DP=262 GT:AD:DP ./.:0:0 chr1 11101 . C . . . AN=384;DP=267 GT:AD:DP ./.:0:0 chr1 11102 . T . . . AN=276;DP=272 GT:AD:DP ./.:0:0 chr1 11103 . C . . . AN=392;DP=277 GT:AD:DP ./.:0:0 chr1 11104 . A . . . AN=242;DP=279 GT:AD:DP ./.:0:0 chr1 11105 . C . . . AN=398;DP=283 GT:AD:DP ./.:0:0 chr1 11106 . G . . . AN=416;DP=290 GT:AD:DP ./.:0:0 chr1 11107 . T . . . AN=300;DP=291 GT:AD:DP ./.:0:0 chr1 11108 . C . . . AN=394;DP=297 GT:AD:DP ./.:0:0 chr1 11109 . A . . . AN=348;DP=301 GT:AD:DP ./.:0:0 chr1 11110 . C . . . AN=404;DP=302 GT:AD:DP ./.:0:0 chr1 11111 . G . . . AN=438;DP=313 GT:AD:DP ./.:0:0 chr1 11112 . G . . . AN=438;DP=314 GT:AD:DP ./.:0:0 chr1 11113 . T . . . AN=326;DP=318 GT:AD:DP ./.:0:0 chr1 11114 . G . . . AN=460;DP=323 GT:AD:DP ./.:0:0 chr1 11115 . G . . . AN=444;DP=325 GT:AD:DP ./.:0:0 chr1 11116 . C . . . AN=406;DP=325 GT:AD:DP ./.:0:0 chr1 11117 . G . . . AN=458;DP=330 GT:AD:DP ./.:0:0 chr1 11118 . C . . . AN=450;DP=328 GT:AD:DP ./.:0:0 chr1 11119 . G . . . AN=482;DP=329 GT:AD:DP ./.:0:0 chr1 11120 . G . . . AN=482;DP=330 GT:AD:DP ./.:0:0 chr1 11121 . C . . . AN=488;DP=334 GT:AD:DP ./.:0:0 chr1 11122 . G . . . AN=490;DP=337 GT:AD:DP ./.:0:0 chr1 11123 . C . . . AN=484;DP=341 GT:AD:DP ./.:0:0 chr1 11124 . A . . . AN=468;DP=343 GT:AD:DP ./.:0:0 chr1 11125 . G . . . AN=480;DP=344 GT:AD:DP ./.:0:0 chr1 11126 . A . . . AN=460;DP=346 GT:AD:DP ./.:0:0 chr1 11127 . G . . . AN=496;DP=351 GT:AD:DP ./.:0:0 chr1 11128 . A . . . AN=466;DP=351 GT:AD:DP ./.:0:0 chr1 11129 . C . . . AN=494;DP=353 GT:AD:DP ./.:0:0 chr1 11130 . G . . . AN=500;DP=355 GT:AD:DP ./.:0:0 chr1 11131 . G . . . AN=498;DP=357 GT:AD:DP ./.:0:0 chr1 11132 . G . . . AN=498;DP=359 GT:AD:DP ./.:0:0 chr1 11133 . T . . . AN=476;DP=361 GT:AD:DP ./.:0:0 chr1 11134 . A . . . AN=442;DP=361 GT:AD:DP ./.:0:0 chr1 11135 . G . . . AN=490;DP=361 GT:AD:DP ./.:0:0 chr1 11136 . A . . . AN=482;DP=362 GT:AD:DP ./.:0:0 chr1 11137 . A . . . AN=428;DP=364 GT:AD:DP ./.:0:0 chr1 11138 . C . . . AN=498;DP=365 GT:AD:DP ./.:0:0 chr1 11139 . C . . . AN=502;DP=367 GT:AD:DP ./.:0:0 chr1 11140 . T . . . AN=468;DP=367 GT:AD:DP ./.:0:0 chr1 11141 . C . . . AN=506;DP=369 GT:AD:DP ./.:0:0 chr1 11142 . A . . . AN=488;DP=368 GT:AD:DP ./.:0:0 chr1 11143 . G . . . AN=510;DP=368 GT:AD:DP ./.:0:0 chr1 11144 . T . . . AN=486;DP=376 GT:AD:DP ./.:0:0 chr1 11145 . A . . . AN=508;DP=380 GT:AD:DP ./.:0:0 chr1 11146 . A . . . AN=496;DP=382 GT:AD:DP ./.:0:0 chr1 11147 . T . . . AN=452;DP=386 GT:AD:DP ./.:0:0 chr1 11148 . C . . . AN=522;DP=385 GT:AD:DP ./.:0:0 chr1 11149 . C . . . AN=516;DP=390 GT:AD:DP ./.:0:0 chr1 11150 . G . . . AN=526;DP=393 GT:AD:DP ./.:0:0 chr1 11151 . A . . . AN=504;DP=395 GT:AD:DP ./.:0:0 chr1 11152 . A . . . AN=514;DP=392 GT:AD:DP ./.:0:0 chr1 11153 . A . . . AN=466;DP=394 GT:AD:DP ./.:0:0 chr1 11154 . A . . . AN=470;DP=394 GT:AD:DP ./.:0:0 chr1 11155 . G . . . AN=526;DP=398 GT:AD:DP ./.:0:0 chr1 11156 . C . . . AN=518;DP=398 GT:AD:DP ./.:0:0 chr1 11157 . C . . . AN=520;DP=400 GT:AD:DP ./.:0:0 chr1 11158 . G . . . AN=528;DP=401 GT:AD:DP ./.:0:0 chr1 11159 . G . . . AN=526;DP=404 GT:AD:DP ./.:0:0 chr1 11160 . G . . . AN=518;DP=406 GT:AD:DP ./.:0:0 chr1 11161 . A . . . AN=510;DP=405 GT:AD:DP ./.:0:0 chr1 11162 . T . . . AN=492;DP=405 GT:AD:DP ./.:0:0 chr1 11163 . C . . . AN=524;DP=407 GT:AD:DP ./.:0:0 chr1 11164 . G . . . AN=526;DP=405 GT:AD:DP ./.:0:0 chr1 11165 . A . . . AN=450;DP=404 GT:AD:DP ./.:0:0 chr1 11166 . C . . . AN=526;DP=409 GT:AD:DP ./.:0:0 chr1 11167 . C . . . AN=524;DP=409 GT:AD:DP ./.:0:0 chr1 11168 . G . . . AN=528;DP=409 GT:AD:DP ./.:0:0 chr1 11169 . C . . . AN=530;DP=411 GT:AD:DP ./.:0:0 chr1 11170 . C . . . AN=522;DP=410 GT:AD:DP ./.:0:0 chr1 11171 . C . . . AN=524;DP=409 GT:AD:DP ./.:0:0 chr1 11172 . C . . . AN=518;DP=409 GT:AD:DP ./.:0:0 chr1 11173 . T . . . AN=494;DP=411 GT:AD:DP ./.:0:0 chr1 11174 . T . . . AN=498;DP=411 GT:AD:DP ./.:0:0 chr1 11175 . G . . . AN=520;DP=411 GT:AD:DP ./.:0:0 chr1 11176 . C . . . AN=516;DP=412 GT:AD:DP ./.:0:0 chr1 11177 . T . . . AN=492;DP=412 GT:AD:DP ./.:0:0 chr1 11178 . T . . . AN=494;DP=411 GT:AD:DP ./.:0:0 chr1 11179 . G . . . AN=516;DP=411 GT:AD:DP ./.:0:0 chr1 11180 . C . . . AN=516;DP=412 GT:AD:DP ./.:0:0 chr1 11181 . A . . . AN=488;DP=408 GT:AD:DP ./.:0:0 chr1 11182 . G . . . AN=514;DP=407 GT:AD:DP ./.:0:0 chr1 11183 . C . . . AN=506;DP=405 GT:AD:DP ./.:0:0 chr1 11184 . C . . . AN=508;DP=406 GT:AD:DP ./.:0:0 chr1 11185 . G . . . AN=502;DP=405 GT:AD:DP ./.:0:0 chr1 11186 . G . . . AN=512;DP=407 GT:AD:DP ./.:0:0 chr1 11187 . G . . . AN=508;DP=407 GT:AD:DP ./.:0:0 chr1 11188 . C . . . AN=510;DP=407 GT:AD:DP ./.:0:0 chr1 11189 . A . . . AN=502;DP=407 GT:AD:DP ./.:0:0 chr1 11190 . C . . . AN=504;DP=408 GT:AD:DP ./.:0:0 chr1 11191 . T . . . AN=482;DP=409 GT:AD:DP ./.:0:0 chr1 11192 . A . . . AN=484;DP=409 GT:AD:DP ./.:0:0 chr1 11193 . C . . . AN=508;DP=411 GT:AD:DP ./.:0:0 chr1 11194 . A . . . AN=478;DP=409 GT:AD:DP ./.:0:0 chr1 11195 . G . . . AN=492;DP=410 GT:AD:DP ./.:0:0 chr1 11196 . G . . . AN=490;DP=410 GT:AD:DP ./.:0:0 chr1 11197 . A . . . AN=436;DP=409 GT:AD:DP ./.:0:0 chr1 11198 . C . . . AN=472;DP=408 GT:AD:DP ./.:0:0 chr1 11199 . C . . . AN=488;DP=408 GT:AD:DP ./.:0:0 chr1 11200 . C . . . AN=468;DP=402 GT:AD:DP ./.:0:0 chr1 11201 . G . . . AN=472;DP=399 GT:AD:DP ./.:0:0 chr1 11202 . C . . . AN=472;DP=394 GT:AD:DP ./.:0:0 chr1 11203 . T . . . AN=420;DP=393 GT:AD:DP ./.:0:0 chr1 11204 . T . . . AN=430;DP=391 GT:AD:DP ./.:0:0 chr1 11205 . G . . . AN=450;DP=383 GT:AD:DP ./.:0:0 chr1 11206 . C . . . AN=448;DP=380 GT:AD:DP ./.:0:0 chr1 11207 . T . . . AN=420;DP=379 GT:AD:DP ./.:0:0 chr1 11208 . C . . . AN=442;DP=378 GT:AD:DP ./.:0:0 chr1 11209 . A . . . AN=420;DP=373 GT:AD:DP ./.:0:0 chr1 11210 . C . . . AN=424;DP=368 GT:AD:DP ./.:0:0 chr1 11211 . G . . . AN=430;DP=361 GT:AD:DP ./.:0:0 chr1 11212 . G . . . AN=428;DP=359 GT:AD:DP ./.:0:0 chr1 11213 . T . . . AN=414;DP=357 GT:AD:DP ./.:0:0 chr1 11214 . G . . . AN=420;DP=352 GT:AD:DP ./.:0:0 chr1 11215 . C . . . AN=416;DP=349 GT:AD:DP ./.:0:0 chr1 11216 . T . . . AN=396;DP=346 GT:AD:DP ./.:0:0 chr1 11217 . G . . . AN=418;DP=338 GT:AD:DP ./.:0:0 chr1 11218 . T . . . AN=388;DP=334 GT:AD:DP ./.:0:0 chr1 11219 . G . . . AN=416;DP=329 GT:AD:DP ./.:0:0 chr1 11220 . C . . . AN=410;DP=326 GT:AD:DP ./.:0:0 chr1 11221 . C . . . AN=404;DP=323 GT:AD:DP ./.:0:0 chr1 11222 . A . . . AN=388;DP=321 GT:AD:DP ./.:0:0 chr1 11223 . G . . . AN=404;DP=322 GT:AD:DP ./.:0:0 chr1 11224 . G . . . AN=404;DP=320 GT:AD:DP ./.:0:0 chr1 11225 . G . . . AN=402;DP=317 GT:AD:DP ./.:0:0 chr1 11226 . C . . . AN=398;DP=313 GT:AD:DP ./.:0:0 chr1 11227 . G . . . AN=394;DP=311 GT:AD:DP ./.:0:0 chr1 11228 . C . . . AN=392;DP=308 GT:AD:DP ./.:0:0 chr1 11229 . C . . . AN=374;DP=308 GT:AD:DP ./.:0:0 chr1 11230 . C . . . AN=374;DP=308 GT:AD:DP ./.:0:0 chr1 11231 . C . . . AN=362;DP=303 GT:AD:DP ./.:0:0 chr1 11232 . C . . . AN=364;DP=301 GT:AD:DP ./.:0:0 chr1 11233 . T . . . AN=350;DP=299 GT:AD:DP ./.:0:0 chr1 11234 . G . . . AN=368;DP=297 GT:AD:DP ./.:0:0 chr1 11235 . C . . . AN=360;DP=292 GT:AD:DP ./.:0:0 chr1 11236 . T . . . AN=340;DP=292 GT:AD:DP ./.:0:0 chr1 11237 . G . . . AN=350;DP=287 GT:AD:DP ./.:0:0 chr1 11238 . G . . . AN=350;DP=281 GT:AD:DP ./.:0:0 chr1 11239 . C . . . AN=348;DP=278 GT:AD:DP ./.:0:0 chr1 11240 . G . . . AN=350;DP=274 GT:AD:DP ./.:0:0 chr1 11241 . A . . . AN=312;DP=271 GT:AD:DP ./.:0:0 chr1 11242 . C . . . AN=330;DP=271 GT:AD:DP ./.:0:0 chr1 11243 . T . . . AN=318;DP=267 GT:AD:DP ./.:0:0 chr1 11244 . A . . . AN=324;DP=265 GT:AD:DP ./.:0:0 chr1 11245 . G . . . AN=328;DP=261 GT:AD:DP ./.:0:0 chr1 11246 . G . . . AN=314;DP=260 GT:AD:DP ./.:0:0 chr1 11247 . G . . . AN=314;DP=254 GT:AD:DP ./.:0:0 chr1 11248 . C . . . AN=312;DP=251 GT:AD:DP ./.:0:0 chr1 11249 . A . . . AN=304;DP=247 GT:AD:DP ./.:0:0 chr1 11250 . A . . . AN=288;DP=247 GT:AD:DP ./.:0:0 chr1 11251 . C . . . AN=286;DP=245 GT:AD:DP ./.:0:0 chr1 11252 . T . . . AN=268;DP=240 GT:AD:DP ./.:0:0 chr1 11253 . G . . . AN=284;DP=238 GT:AD:DP ./.:0:0 chr1 11254 . C . . . AN=274;DP=233 GT:AD:DP ./.:0:0 chr1 11255 . A . . . AN=258;DP=232 GT:AD:DP ./.:0:0 chr1 11256 . G . . . AN=258;DP=227 GT:AD:DP ./.:0:0 chr1 11257 . G . . . AN=258;DP=224 GT:AD:DP ./.:0:0 chr1 11258 . G . . . AN=246;DP=221 GT:AD:DP ./.:0:0 chr1 11259 . C . . . AN=242;DP=213 GT:AD:DP ./.:0:0 chr1 11260 . T . . . AN=230;DP=210 GT:AD:DP ./.:0:0 chr1 11261 . C . . . AN=242;DP=206 GT:AD:DP ./.:0:0 chr1 11262 . T . . . AN=234;DP=199 GT:AD:DP ./.:0:0 chr1 11263 . C . . . AN=244;DP=198 GT:AD:DP ./.:0:0 chr1 11264 . T . . . AN=226;DP=193 GT:AD:DP ./.:0:0 chr1 11265 . T . . . AN=226;DP=188 GT:AD:DP ./.:0:0 chr1 11266 . G . . . AN=234;DP=186 GT:AD:DP ./.:0:0 chr1 11267 . C . . . AN=232;DP=178 GT:AD:DP ./.:0:0 chr1 11268 . T . . . AN=214;DP=174 GT:AD:DP ./.:0:0 chr1 11269 . T . . . AN=216;DP=173 GT:AD:DP ./.:0:0 chr1 11270 . A . . . AN=212;DP=171 GT:AD:DP ./.:0:0 chr1 11271 . G . . . AN=218;DP=171 GT:AD:DP ./.:0:0 chr1 11272 . A . . . AN=194;DP=164 GT:AD:DP ./.:0:0 chr1 11273 . G . . . AN=208;DP=163 GT:AD:DP ./.:0:0 chr1 11274 . T . . . AN=204;DP=159 GT:AD:DP ./.:0:0 chr1 11275 . G . . . AN=204;DP=157 GT:AD:DP ./.:0:0 chr1 11276 . G . . . AN=206;DP=157 GT:AD:DP ./.:0:0 chr1 11277 . T . . . AN=196;DP=154 GT:AD:DP ./.:0:0 chr1 11278 . G . . . AN=202;DP=149 GT:AD:DP ./.:0:0 chr1 11279 . G . . . AN=200;DP=148 GT:AD:DP ./.:0:0 chr1 11280 . C . . . AN=192;DP=145 GT:AD:DP ./.:0:0 chr1 11281 . C . . . AN=188;DP=143 GT:AD:DP ./.:0:0 chr1 11282 . A . . . AN=178;DP=141 GT:AD:DP ./.:0:0 chr1 11283 . G . . . AN=190;DP=138 GT:AD:DP ./.:0:0 chr1 11284 . C . . . AN=190;DP=136 GT:AD:DP ./.:0:0 chr1 11285 . G . . . AN=166;DP=134 GT:AD:DP ./.:0:0 chr1 11286 . C . . . AN=160;DP=132 GT:AD:DP ./.:0:0 chr1 11287 . C . . . AN=150;DP=131 GT:AD:DP ./.:0:0 chr1 11288 . C . . . AN=156;DP=128 GT:AD:DP ./.:0:0 chr1 11289 . C . . . AN=136;DP=126 GT:AD:DP ./.:0:0 chr1 11290 . C . . . AN=136;DP=124 GT:AD:DP ./.:0:0 chr1 11291 . T . . . AN=124;DP=123 GT:AD:DP ./.:0:0 chr1 11292 . G . . . AN=136;DP=120 GT:AD:DP ./.:0:0 chr1 11293 . C . . . AN=128;DP=118 GT:AD:DP ./.:0:0 chr1 11294 . T . . . AN=110;DP=118 GT:AD:DP ./.:0:0 chr1 11295 . G . . . AN=126;DP=110 GT:AD:DP ./.:0:0 chr1 11296 . G . . . AN=126;DP=102 GT:AD:DP ./.:0:0 chr1 11297 . C . . . AN=122;DP=101 GT:AD:DP ./.:0:0 chr1 11298 . G . . . AN=122;DP=99 GT:AD:DP ./.:0:0 chr1 11299 . C . . . AN=118;DP=98 GT:AD:DP ./.:0:0 chr1 11300 . C . . . AN=114;DP=93 GT:AD:DP ./.:0:0 chr1 11301 . G . . . AN=118;DP=89 GT:AD:DP ./.:0:0 chr1 11302 . G . . . AN=104;DP=87 GT:AD:DP ./.:0:0 chr1 11303 . G . . . AN=104;DP=87 GT:AD:DP ./.:0:0 chr1 11304 . G . . . AN=104;DP=83 GT:AD:DP ./.:0:0 chr1 11305 . C . . . AN=102;DP=81 GT:AD:DP ./.:0:0 chr1 11306 . A . . . AN=100;DP=80 GT:AD:DP ./.:0:0 chr1 11307 . C . . . AN=98;DP=80 GT:AD:DP ./.:0:0 chr1 11308 . T . . . AN=88;DP=78 GT:AD:DP ./.:0:0 chr1 11309 . G . . . AN=98;DP=77 GT:AD:DP ./.:0:0 chr1 11310 . C . . . AN=98;DP=74 GT:AD:DP ./.:0:0 chr1 11311 . A . . . AN=88;DP=72 GT:AD:DP ./.:0:0 chr1 11312 . G . . . AN=96;DP=70 GT:AD:DP ./.:0:0 chr1 11313 . G . . . AN=96;DP=68 GT:AD:DP ./.:0:0 chr1 11314 . G . . . AN=92;DP=67 GT:AD:DP ./.:0:0 chr1 11315 . C . . . AN=88;DP=65 GT:AD:DP ./.:0:0 chr1 11316 . C . . . AN=86;DP=63 GT:AD:DP ./.:0:0 chr1 11317 . C . . . AN=88;DP=61 GT:AD:DP ./.:0:0 chr1 11318 . T . . . AN=84;DP=60 GT:AD:DP ./.:0:0 chr1 11319 . C . . . AN=88;DP=60 GT:AD:DP ./.:0:0 chr1 11320 . T . . . AN=84;DP=59 GT:AD:DP ./.:0:0 chr1 11321 . T . . . AN=80;DP=59 GT:AD:DP ./.:0:0 chr1 11322 . G . . . AN=88;DP=58 GT:AD:DP ./.:0:0 chr1 11323 . C . . . AN=84;DP=58 GT:AD:DP ./.:0:0 chr1 11324 . T . . . AN=84;DP=56 GT:AD:DP ./.:0:0 chr1 11325 . T . . . AN=76;DP=56 GT:AD:DP ./.:0:0 chr1 11326 . A . . . AN=68;DP=55 GT:AD:DP ./.:0:0 chr1 11327 . C . . . AN=76;DP=54 GT:AD:DP ./.:0:0 chr1 11328 . T . . . AN=70;DP=55 GT:AD:DP ./.:0:0 chr1 11329 . G . . . AN=74;DP=55 GT:AD:DP ./.:0:0 chr1 11330 . T . . . AN=70;DP=53 GT:AD:DP ./.:0:0 chr1 11331 . A . . . AN=62;DP=53 GT:AD:DP ./.:0:0 chr1 11332 . T . . . AN=58;DP=53 GT:AD:DP ./.:0:0 chr1 11333 . A . . . AN=60;DP=51 GT:AD:DP ./.:0:0 chr1 11334 . G . . . AN=54;DP=51 GT:AD:DP ./.:0:0 chr1 11335 . T . . . AN=44;DP=48 GT:AD:DP ./.:0:0 chr1 11336 . G . . . AN=54;DP=46 GT:AD:DP ./.:0:0 chr1 11337 . G . . . AN=52;DP=44 GT:AD:DP ./.:0:0 chr1 11338 . T . . . AN=50;DP=43 GT:AD:DP ./.:0:0 chr1 11339 . G . . . AN=50;DP=42 GT:AD:DP ./.:0:0 chr1 11340 . G . . . AN=50;DP=41 GT:AD:DP ./.:0:0 chr1 11341 . C . . . AN=48;DP=39 GT:AD:DP ./.:0:0 chr1 11342 . A . . . AN=36;DP=36 GT:AD:DP ./.:0:0 chr1 11343 . C . . . AN=46;DP=35 GT:AD:DP ./.:0:0 chr1 11344 . G . . . AN=46;DP=32 GT:AD:DP ./.:0:0 chr1 11345 . C . . . AN=46;DP=31 GT:AD:DP ./.:0:0 chr1 11346 . C . . . AN=46;DP=30 GT:AD:DP ./.:0:0 chr1 11347 . G . . . AN=44;DP=29 GT:AD:DP ./.:0:0 chr1 11348 . C . . . AN=44;DP=29 GT:AD:DP ./.:0:0 chr1 11349 . C . . . AN=38;DP=29 GT:AD:DP ./.:0:0 chr1 11350 . T . . . AN=40;DP=28 GT:AD:DP ./.:0:0 chr1 11351 . G . . . AN=42;DP=29 GT:AD:DP ./.:0:0 chr1 11352 . C . . . AN=42;DP=27 GT:AD:DP ./.:0:0 chr1 11353 . T . . . AN=38;DP=27 GT:AD:DP ./.:0:0 chr1 11354 . G . . . AN=40;DP=27 GT:AD:DP ./.:0:0 chr1 11355 . G . . . AN=38;DP=27 GT:AD:DP ./.:0:0 chr1 11356 . C . . . AN=38;DP=27 GT:AD:DP ./.:0:0 chr1 11357 . A . . . AN=34;DP=27 GT:AD:DP ./.:0:0 chr1 11358 . G . . . AN=38;DP=26 GT:AD:DP ./.:0:0 chr1 11359 . C . . . AN=34;DP=25 GT:AD:DP ./.:0:0 chr1 11360 . T . . . AN=34;DP=24 GT:AD:DP ./.:0:0 chr1 11361 . A . . . AN=32;DP=23 GT:AD:DP ./.:0:0 chr1 11362 . G . . . AN=34;DP=24 GT:AD:DP ./.:0:0 chr1 11363 . G . . . AN=32;DP=23 GT:AD:DP ./.:0:0 chr1 11364 . G . . . AN=32;DP=23 GT:AD:DP ./.:0:0 chr1 11365 . A . . . AN=28;DP=23 GT:AD:DP ./.:0:0 chr1 11366 . C . . . AN=28;DP=23 GT:AD:DP ./.:0:0 chr1 11367 . A . . . AN=22;DP=23 GT:AD:DP ./.:0:0 chr1 11368 . T . . . AN=28;DP=23 GT:AD:DP ./.:0:0 chr1 11369 . T . . . AN=28;DP=23 GT:AD:DP ./.:0:0 chr1 11370 . G . . . AN=28;DP=22 GT:AD:DP ./.:0:0 chr1 11371 . C . . . AN=28;DP=20 GT:AD:DP ./.:0:0 chr1 11372 . A . . . AN=26;DP=19 GT:AD:DP ./.:0:0 chr1 11373 . G . . . AN=28;DP=17 GT:AD:DP ./.:0:0 chr1 11374 . G . . . AN=28;DP=17 GT:AD:DP ./.:0:0 chr1 11375 . G . . . AN=28;DP=17 GT:AD:DP ./.:0:0 chr1 11376 . T . . . AN=26;DP=16 GT:AD:DP ./.:0:0 chr1 11377 . C . . . AN=28;DP=14 GT:AD:DP ./.:0:0 chr1 11378 . C . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 11379 . T . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 11380 . C . . . AN=24;DP=14 GT:AD:DP ./.:0:0 chr1 11381 . T . . . AN=20;DP=14 GT:AD:DP ./.:0:0 chr1 11382 . T . . . AN=22;DP=14 GT:AD:DP ./.:0:0 chr1 11383 . G . . . AN=22;DP=14 GT:AD:DP ./.:0:0 chr1 11384 . C . . . AN=22;DP=14 GT:AD:DP ./.:0:0 chr1 11385 . T . . . AN=18;DP=14 GT:AD:DP ./.:0:0 chr1 11386 . C . . . AN=22;DP=14 GT:AD:DP ./.:0:0 chr1 11387 . A . . . AN=20;DP=14 GT:AD:DP ./.:0:0 chr1 11388 . A . . . AN=22;DP=13 GT:AD:DP ./.:0:0 chr1 11389 . G . . . AN=20;DP=13 GT:AD:DP ./.:0:0 chr1 11390 . G . . . AN=20;DP=12 GT:AD:DP ./.:0:0 chr1 11391 . T . . . AN=16;DP=12 GT:AD:DP ./.:0:0 chr1 11392 . G . . . AN=18;DP=11 GT:AD:DP ./.:0:0 chr1 11393 . T . . . AN=16;DP=11 GT:AD:DP ./.:0:0 chr1 11394 . A . . . AN=16;DP=11 GT:AD:DP ./.:0:0 chr1 11395 . G . . . AN=16;DP=11 GT:AD:DP ./.:0:0 chr1 11396 . T . . . AN=16;DP=11 GT:AD:DP ./.:0:0 chr1 11397 . G . . . AN=14;DP=11 GT:AD:DP ./.:0:0 chr1 11398 . G . . . AN=16;DP=11 GT:AD:DP ./.:0:0 chr1 11399 . C . . . AN=14;DP=10 GT:AD:DP ./.:0:0 chr1 11400 . A . . . AN=14;DP=10 GT:AD:DP ./.:0:0 chr1 11401 . G . . . AN=14;DP=10 GT:AD:DP ./.:0:0 chr1 11402 . C . . . AN=14;DP=10 GT:AD:DP ./.:0:0 chr1 11403 . A . . . AN=10;DP=9 GT:AD:DP ./.:0:0 chr1 11404 . C . . . AN=12;DP=9 GT:AD:DP ./.:0:0 chr1 11405 . G . . . AN=12;DP=8 GT:AD:DP ./.:0:0 chr1 11406 . C . . . AN=12;DP=8 GT:AD:DP ./.:0:0 chr1 11407 . C . . . AN=12;DP=8 GT:AD:DP ./.:0:0 chr1 11408 . C . . . AN=10;DP=8 GT:AD:DP ./.:0:0 chr1 11409 . A . . . AN=8;DP=8 GT:AD:DP ./.:0:0 chr1 11410 . C . . . AN=12;DP=7 GT:AD:DP ./.:0:0 chr1 11411 . C . . . AN=12;DP=7 GT:AD:DP ./.:0:0 chr1 11412 . T . . . AN=12;DP=7 GT:AD:DP ./.:0:0 chr1 11413 . G . . . AN=10;DP=6 GT:AD:DP ./.:0:0 chr1 11414 . C . . . AN=10;DP=6 GT:AD:DP ./.:0:0 chr1 11415 . T . . . AN=10;DP=6 GT:AD:DP ./.:0:0 chr1 11416 . G . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11417 . G . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11418 . C . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11419 . A . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11420 . G . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11421 . C . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11422 . T . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11423 . G . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11424 . G . . . AN=8;DP=6 GT:AD:DP ./.:0:0 chr1 11425 . G . . . AN=8;DP=5 GT:AD:DP ./.:0:0 chr1 11426 . G . . . AN=8;DP=5 GT:AD:DP ./.:0:0 chr1 11427 . A . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11428 . C . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11429 . A . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11430 . C . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11431 . T . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11432 . G . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11433 . C . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11434 . C . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11435 . G . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11436 . G . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11437 . G . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 11438 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11439 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11440 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11441 . T . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11442 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11443 . T . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11444 . T . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11445 . G . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11446 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11447 . T . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11448 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11449 . C . . . AN=6;DP=4 GT:AD:DP ./.:0:0 chr1 11450 . A . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11451 . A . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11452 . C . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11453 . A . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11454 . G . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11455 . T . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11456 . A . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11457 . C . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11458 . T . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11459 . G . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11460 . G . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11461 . C . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 11462 . G . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11463 . G . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11464 . A . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11465 . T . . . AN=2;DP=3 GT:AD:DP ./.:0:0 chr1 11466 . T . . . AN=2;DP=3 GT:AD:DP ./.:0:0 chr1 11467 . A . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11468 . T . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11469 . A . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11470 . G . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11471 . G . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11472 . G . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11473 . A . . . AN=4;DP=3 GT:AD:DP ./.:0:0 chr1 11474 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11475 . A . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11476 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11477 . A . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11478 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11479 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11480 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11481 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11482 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11483 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11484 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11485 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11486 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11487 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11488 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11489 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11490 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 11491 . C . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11492 . T . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11493 . G . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11494 . T . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11495 . T . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11496 . T . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11497 . G . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11498 . G . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11499 . T . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11500 . C . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11501 . T . . . AN=2;DP=2 GT:AD:DP ./.:0:0 chr1 11502 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11503 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11504 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11505 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11506 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11507 . G . . . DP=1 GT:AD:DP ./.:0:0 chr1 11508 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11509 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11510 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11511 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11512 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11513 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11514 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11515 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11516 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11517 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11518 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11519 . T . . . . GT:AD:DP ./.:0:0 chr1 11520 . G . . . . GT:AD:DP ./.:0:0 chr1 11521 . G . . . . GT:AD:DP ./.:0:0 chr1 11522 . G . . . . GT:AD:DP ./.:0:0 chr1 11523 . A . . . . GT:AD:DP ./.:0:0 chr1 11524 . T . . . . GT:AD:DP ./.:0:0 chr1 11525 . T . . . . GT:AD:DP ./.:0:0 chr1 11526 . C . . . . GT:AD:DP ./.:0:0 chr1 11527 . C . . . . GT:AD:DP ./.:0:0 chr1 11528 . T . . . . GT:AD:DP ./.:0:0 chr1 11529 . G . . . . GT:AD:DP ./.:0:0 chr1 11530 . G . . . . GT:AD:DP ./.:0:0 chr1 11531 . G . . . . GT:AD:DP ./.:0:0 chr1 11532 . T . . . . GT:AD:DP ./.:0:0 chr1 11533 . T . . . . GT:AD:DP ./.:0:0 chr1 11534 . T . . . . GT:AD:DP ./.:0:0 chr1 11535 . A . . . . GT:AD:DP ./.:0:0 chr1 11536 . A . . . . GT:AD:DP ./.:0:0 chr1 11537 . A . . . . GT:AD:DP ./.:0:0 chr1 11538 . A . . . . GT:AD:DP ./.:0:0 chr1 11539 . G . . . . GT:AD:DP ./.:0:0 chr1 11540 . T . . . . GT:AD:DP ./.:0:0 chr1 11541 . A . . . . GT:AD:DP ./.:0:0 chr1 11542 . A . . . . GT:AD:DP ./.:0:0 chr1 11543 . A . . . . GT:AD:DP ./.:0:0 chr1 11544 . A . . . . GT:AD:DP ./.:0:0 chr1 11545 . A . . . . GT:AD:DP ./.:0:0 chr1 11546 . A . . . . GT:AD:DP ./.:0:0 chr1 11547 . T . . . . GT:AD:DP ./.:0:0 chr1 11548 . A . . . . GT:AD:DP ./.:0:0 chr1 11549 . A . . . . GT:AD:DP ./.:0:0 chr1 11550 . A . . . . GT:AD:DP ./.:0:0 chr1 11551 . T . . . . GT:AD:DP ./.:0:0 chr1 11552 . A . . . . GT:AD:DP ./.:0:0 chr1 11553 . T . . . . GT:AD:DP ./.:0:0 chr1 11554 . G . . . . GT:AD:DP ./.:0:0 chr1 11555 . T . . . . GT:AD:DP ./.:0:0 chr1 11556 . T . . . . GT:AD:DP ./.:0:0 chr1 11557 . T . . . . GT:AD:DP ./.:0:0 chr1 11558 . A . . . . GT:AD:DP ./.:0:0 chr1 11559 . A . . . . GT:AD:DP ./.:0:0 chr1 11560 . T . . . . GT:AD:DP ./.:0:0 chr1 11561 . T . . . . GT:AD:DP ./.:0:0 chr1 11562 . T . . . . GT:AD:DP ./.:0:0 chr1 11563 . G . . . . GT:AD:DP ./.:0:0 chr1 11564 . T . . . . GT:AD:DP ./.:0:0 chr1 11565 . G . . . . GT:AD:DP ./.:0:0 chr1 11566 . A . . . . GT:AD:DP ./.:0:0 chr1 11567 . A . . . . GT:AD:DP ./.:0:0 chr1 11568 . C . . . . GT:AD:DP ./.:0:0 chr1 11569 . T . . . . GT:AD:DP ./.:0:0 chr1 11570 . G . . . . GT:AD:DP ./.:0:0 chr1 11571 . A . . . . GT:AD:DP ./.:0:0 chr1 11572 . T . . . . GT:AD:DP ./.:0:0 chr1 11573 . T . . . . GT:AD:DP ./.:0:0 chr1 11574 . A . . . . GT:AD:DP ./.:0:0 chr1 11575 . C . . . . GT:AD:DP ./.:0:0 chr1 11576 . C . . . . GT:AD:DP ./.:0:0 chr1 11577 . A . . . . GT:AD:DP ./.:0:0 chr1 11578 . T . . . . GT:AD:DP ./.:0:0 chr1 11579 . C . . . . GT:AD:DP ./.:0:0 chr1 11580 . A . . . . GT:AD:DP ./.:0:0 chr1 11581 . G . . . . GT:AD:DP ./.:0:0 chr1 11582 . A . . . . GT:AD:DP ./.:0:0 chr1 11583 . A . . . . GT:AD:DP ./.:0:0 chr1 11584 . T . . . . GT:AD:DP ./.:0:0 chr1 11585 . T . . . . GT:AD:DP ./.:0:0 chr1 11586 . G . . . . GT:AD:DP ./.:0:0 chr1 11587 . T . . . . GT:AD:DP ./.:0:0 chr1 11588 . A . . . . GT:AD:DP ./.:0:0 chr1 11589 . C . . . . GT:AD:DP ./.:0:0 chr1 11590 . T . . . . GT:AD:DP ./.:0:0 chr1 11591 . G . . . . GT:AD:DP ./.:0:0 chr1 11592 . T . . . . GT:AD:DP ./.:0:0 chr1 11593 . T . . . . GT:AD:DP ./.:0:0 chr1 11594 . C . . . . GT:AD:DP ./.:0:0 chr1 11595 . T . . . . GT:AD:DP ./.:0:0 chr1 11596 . G . . . . GT:AD:DP ./.:0:0 chr1 11597 . T . . . . GT:AD:DP ./.:0:0 chr1 11598 . A . . . . GT:AD:DP ./.:0:0 chr1 11599 . T . . . . GT:AD:DP ./.:0:0 chr1 11600 . C . . . . GT:AD:DP ./.:0:0 chr1 11601 . C . . . . GT:AD:DP ./.:0:0 chr1 11602 . C . . . . GT:AD:DP ./.:0:0 chr1 11603 . A . . . . GT:AD:DP ./.:0:0 chr1 11604 . C . . . . GT:AD:DP ./.:0:0 chr1 11605 . C . . . . GT:AD:DP ./.:0:0 chr1 11606 . A . . . . GT:AD:DP ./.:0:0 chr1 11607 . G . . . . GT:AD:DP ./.:0:0 chr1 11608 . C . . . . GT:AD:DP ./.:0:0 chr1 11609 . A . . . . GT:AD:DP ./.:0:0 chr1 11610 . A . . . . GT:AD:DP ./.:0:0 chr1 11611 . T . . . . GT:AD:DP ./.:0:0 chr1 11612 . G . . . . GT:AD:DP ./.:0:0 chr1 11613 . T . . . . GT:AD:DP ./.:0:0 chr1 11614 . C . . . . GT:AD:DP ./.:0:0 chr1 11615 . T . . . . GT:AD:DP ./.:0:0 chr1 11616 . A . . . . GT:AD:DP ./.:0:0 chr1 11617 . G . . . . GT:AD:DP ./.:0:0 chr1 11618 . G . . . . GT:AD:DP ./.:0:0 chr1 11619 . A . . . . GT:AD:DP ./.:0:0 chr1 11620 . A . . . . GT:AD:DP ./.:0:0 chr1 11621 . T . . . . GT:AD:DP ./.:0:0 chr1 11622 . G . . . . GT:AD:DP ./.:0:0 chr1 11623 . C . . . . GT:AD:DP ./.:0:0 chr1 11624 . C . . . . GT:AD:DP ./.:0:0 chr1 11625 . T . . . . GT:AD:DP ./.:0:0 chr1 11626 . G . . . . GT:AD:DP ./.:0:0 chr1 11627 . T . . . . GT:AD:DP ./.:0:0 chr1 11628 . T . . . . GT:AD:DP ./.:0:0 chr1 11629 . T . . . . GT:AD:DP ./.:0:0 chr1 11630 . C . . . . GT:AD:DP ./.:0:0 chr1 11631 . T . . . . GT:AD:DP ./.:0:0 chr1 11632 . C . . . . GT:AD:DP ./.:0:0 chr1 11633 . C . . . . GT:AD:DP ./.:0:0 chr1 11634 . A . . . . GT:AD:DP ./.:0:0 chr1 11635 . C . . . . GT:AD:DP ./.:0:0 chr1 11636 . A . . . . GT:AD:DP ./.:0:0 chr1 11637 . A . . . . GT:AD:DP ./.:0:0 chr1 11638 . A . . . . GT:AD:DP ./.:0:0 chr1 11639 . G . . . . GT:AD:DP ./.:0:0 chr1 11640 . T . . . . GT:AD:DP ./.:0:0 chr1 11641 . G . . . . GT:AD:DP ./.:0:0 chr1 11642 . T . . . . GT:AD:DP ./.:0:0 chr1 11643 . T . . . . GT:AD:DP ./.:0:0 chr1 11644 . T . . . . GT:AD:DP ./.:0:0 chr1 11645 . A . . . . GT:AD:DP ./.:0:0 chr1 11646 . C . . . . GT:AD:DP ./.:0:0 chr1 11647 . T . . . . GT:AD:DP ./.:0:0 chr1 11648 . T . . . . GT:AD:DP ./.:0:0 chr1 11649 . T . . . . GT:AD:DP ./.:0:0 chr1 11650 . T . . . . GT:AD:DP ./.:0:0 chr1 11651 . G . . . . GT:AD:DP ./.:0:0 chr1 11652 . G . . . . GT:AD:DP ./.:0:0 chr1 11653 . A . . . . GT:AD:DP ./.:0:0 chr1 11654 . T . . . . GT:AD:DP ./.:0:0 chr1 11655 . T . . . . GT:AD:DP ./.:0:0 chr1 11656 . T . . . . GT:AD:DP ./.:0:0 chr1 11657 . T . . . . GT:AD:DP ./.:0:0 chr1 11658 . T . . . . GT:AD:DP ./.:0:0 chr1 11659 . G . . . . GT:AD:DP ./.:0:0 chr1 11660 . C . . . . GT:AD:DP ./.:0:0 chr1 11661 . C . . . . GT:AD:DP ./.:0:0 chr1 11662 . A . . . . GT:AD:DP ./.:0:0 chr1 11663 . G . . . . GT:AD:DP ./.:0:0 chr1 11664 . T . . . . GT:AD:DP ./.:0:0 chr1 11665 . C . . . . GT:AD:DP ./.:0:0 chr1 11666 . T . . . . GT:AD:DP ./.:0:0 chr1 11667 . A . . . . GT:AD:DP ./.:0:0 chr1 11668 . A . . . . GT:AD:DP ./.:0:0 chr1 11669 . C . . . . GT:AD:DP ./.:0:0 chr1 11670 . A . . . . GT:AD:DP ./.:0:0 chr1 11671 . G . . . . GT:AD:DP ./.:0:0 chr1 11672 . G . . . . GT:AD:DP ./.:0:0 chr1 11673 . T . . . . GT:AD:DP ./.:0:0 chr1 11674 . G . . . . GT:AD:DP ./.:0:0 chr1 11675 . A . . . . GT:AD:DP ./.:0:0 chr1 11676 . A . . . . GT:AD:DP ./.:0:0 chr1 11677 . G . . . . GT:AD:DP ./.:0:0 chr1 11678 . C . . . . GT:AD:DP ./.:0:0 chr1 11679 . C . . . . GT:AD:DP ./.:0:0 chr1 11680 . C . . . . GT:AD:DP ./.:0:0 chr1 11681 . T . . . . GT:AD:DP ./.:0:0 chr1 11682 . G . . . . GT:AD:DP ./.:0:0 chr1 11683 . G . . . . GT:AD:DP ./.:0:0 chr1 11684 . A . . . . GT:AD:DP ./.:0:0 chr1 11685 . G . . . . GT:AD:DP ./.:0:0 chr1 11686 . A . . . . GT:AD:DP ./.:0:0 chr1 11687 . T . . . . GT:AD:DP ./.:0:0 chr1 11688 . T . . . . GT:AD:DP ./.:0:0 chr1 11689 . C . . . . GT:AD:DP ./.:0:0 chr1 11690 . T . . . . GT:AD:DP ./.:0:0 chr1 11691 . T . . . . GT:AD:DP ./.:0:0 chr1 11692 . A . . . . GT:AD:DP ./.:0:0 chr1 11693 . T . . . . GT:AD:DP ./.:0:0 chr1 11694 . T . . . . GT:AD:DP ./.:0:0 chr1 11695 . A . . . . GT:AD:DP ./.:0:0 chr1 11696 . G . . . . GT:AD:DP ./.:0:0 chr1 11697 . T . . . . GT:AD:DP ./.:0:0 chr1 11698 . G . . . . GT:AD:DP ./.:0:0 chr1 11699 . A . . . . GT:AD:DP ./.:0:0 chr1 11700 . T . . . . GT:AD:DP ./.:0:0 chr1 11701 . T . . . . GT:AD:DP ./.:0:0 chr1 11702 . T . . . . GT:AD:DP ./.:0:0 chr1 11703 . G . . . . GT:AD:DP ./.:0:0 chr1 11704 . G . . . . GT:AD:DP ./.:0:0 chr1 11705 . G . . . . GT:AD:DP ./.:0:0 chr1 11706 . C . . . . GT:AD:DP ./.:0:0 chr1 11707 . T . . . . GT:AD:DP ./.:0:0 chr1 11708 . G . . . . GT:AD:DP ./.:0:0 chr1 11709 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11710 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11711 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11712 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11713 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11714 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11715 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11716 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11717 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11718 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11719 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11720 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11721 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11722 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11723 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11724 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11725 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11726 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11727 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11728 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11729 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11730 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11731 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11732 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11733 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11734 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11735 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11736 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11737 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11738 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11739 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11740 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11741 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11742 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11743 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11744 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11745 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11746 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11747 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11748 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11749 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11750 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11751 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11752 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11753 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11754 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11755 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11756 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11757 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11758 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11759 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11760 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11761 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11762 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11763 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11764 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11765 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11766 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11767 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11768 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11769 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11770 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11771 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11772 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11773 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11774 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11775 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11776 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11777 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11778 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11779 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11780 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11781 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11782 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11783 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11784 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11785 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11786 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11787 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11788 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11789 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11790 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11791 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11792 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11793 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11794 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11795 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11796 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11797 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11798 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11799 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11800 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11801 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11802 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11803 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11804 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11805 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11806 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11807 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11808 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11809 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11810 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11811 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11812 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11813 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11814 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11815 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11816 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11817 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11818 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11819 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11820 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11821 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11822 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11823 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11824 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11825 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11826 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11827 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11828 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11829 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11830 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11831 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11832 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11833 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11834 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11835 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11836 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11837 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11838 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11839 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11840 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11841 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11842 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11843 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11844 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11845 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11846 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11847 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11848 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 11849 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11850 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11851 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11852 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11853 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11854 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11855 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11856 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 11857 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 11858 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11859 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 11860 . T . . . . GT:AD:DP ./.:0:0 chr1 11861 . T . . . . GT:AD:DP ./.:0:0 chr1 11862 . T . . . . GT:AD:DP ./.:0:0 chr1 11863 . C . . . . GT:AD:DP ./.:0:0 chr1 11864 . T . . . . GT:AD:DP ./.:0:0 chr1 11865 . T . . . . GT:AD:DP ./.:0:0 chr1 11866 . T . . . . GT:AD:DP ./.:0:0 chr1 11867 . T . . . . GT:AD:DP ./.:0:0 chr1 11868 . C . . . . GT:AD:DP ./.:0:0 chr1 11869 . G . . . . GT:AD:DP ./.:0:0 chr1 11870 . T . . . . GT:AD:DP ./.:0:0 chr1 11871 . T . . . . GT:AD:DP ./.:0:0 chr1 11872 . A . . . . GT:AD:DP ./.:0:0 chr1 11873 . A . . . . GT:AD:DP ./.:0:0 chr1 11874 . C . . . . GT:AD:DP ./.:0:0 chr1 11875 . T . . . . GT:AD:DP ./.:0:0 chr1 11876 . T . . . . GT:AD:DP ./.:0:0 chr1 11877 . G . . . . GT:AD:DP ./.:0:0 chr1 11878 . C . . . . GT:AD:DP ./.:0:0 chr1 11879 . C . . . . GT:AD:DP ./.:0:0 chr1 11880 . G . . . . GT:AD:DP ./.:0:0 chr1 11881 . T . . . . GT:AD:DP ./.:0:0 chr1 11882 . C . . . . GT:AD:DP ./.:0:0 chr1 11883 . A . . . . GT:AD:DP ./.:0:0 chr1 11884 . G . . . . GT:AD:DP ./.:0:0 chr1 11885 . C . . . . GT:AD:DP ./.:0:0 chr1 11886 . C . . . . GT:AD:DP ./.:0:0 chr1 11887 . T . . . . GT:AD:DP ./.:0:0 chr1 11888 . T . . . . GT:AD:DP ./.:0:0 chr1 11889 . T . . . . GT:AD:DP ./.:0:0 chr1 11890 . T . . . . GT:AD:DP ./.:0:0 chr1 11891 . C . . . . GT:AD:DP ./.:0:0 chr1 11892 . T . . . . GT:AD:DP ./.:0:0 chr1 11893 . T . . . . GT:AD:DP ./.:0:0 chr1 11894 . T . . . . GT:AD:DP ./.:0:0 chr1 11895 . G . . . . GT:AD:DP ./.:0:0 chr1 11896 . A . . . . GT:AD:DP ./.:0:0 chr1 11897 . C . . . . GT:AD:DP ./.:0:0 chr1 11898 . C . . . . GT:AD:DP ./.:0:0 chr1 11899 . T . . . . GT:AD:DP ./.:0:0 chr1 11900 . C . . . . GT:AD:DP ./.:0:0 chr1 11901 . T . . . . GT:AD:DP ./.:0:0 chr1 11902 . T . . . . GT:AD:DP ./.:0:0 chr1 11903 . C . . . . GT:AD:DP ./.:0:0 chr1 11904 . T . . . . GT:AD:DP ./.:0:0 chr1 11905 . T . . . . GT:AD:DP ./.:0:0 chr1 11906 . T . . . . GT:AD:DP ./.:0:0 chr1 11907 . C . . . . GT:AD:DP ./.:0:0 chr1 11908 . T . . . . GT:AD:DP ./.:0:0 chr1 11909 . G . . . . GT:AD:DP ./.:0:0 chr1 11910 . T . . . . GT:AD:DP ./.:0:0 chr1 11911 . T . . . . GT:AD:DP ./.:0:0 chr1 11912 . C . . . . GT:AD:DP ./.:0:0 chr1 11913 . A . . . . GT:AD:DP ./.:0:0 chr1 11914 . T . . . . GT:AD:DP ./.:0:0 chr1 11915 . G . . . . GT:AD:DP ./.:0:0 chr1 11916 . T . . . . GT:AD:DP ./.:0:0 chr1 11917 . G . . . . GT:AD:DP ./.:0:0 chr1 11918 . T . . . . GT:AD:DP ./.:0:0 chr1 11919 . A . . . . GT:AD:DP ./.:0:0 chr1 11920 . T . . . . GT:AD:DP ./.:0:0 chr1 11921 . T . . . . GT:AD:DP ./.:0:0 chr1 11922 . T . . . . GT:AD:DP ./.:0:0 chr1 11923 . G . . . . GT:AD:DP ./.:0:0 chr1 11924 . C . . . . GT:AD:DP ./.:0:0 chr1 11925 . T . . . . GT:AD:DP ./.:0:0 chr1 11926 . G . . . . GT:AD:DP ./.:0:0 chr1 11927 . T . . . . GT:AD:DP ./.:0:0 chr1 11928 . C . . . . GT:AD:DP ./.:0:0 chr1 11929 . T . . . . GT:AD:DP ./.:0:0 chr1 11930 . C . . . . GT:AD:DP ./.:0:0 chr1 11931 . T . . . . GT:AD:DP ./.:0:0 chr1 11932 . T . . . . GT:AD:DP ./.:0:0 chr1 11933 . A . . . . GT:AD:DP ./.:0:0 chr1 11934 . G . . . . GT:AD:DP ./.:0:0 chr1 11935 . C . . . . GT:AD:DP ./.:0:0 chr1 11936 . C . . . . GT:AD:DP ./.:0:0 chr1 11937 . C . . . . GT:AD:DP ./.:0:0 chr1 11938 . A . . . . GT:AD:DP ./.:0:0 chr1 11939 . G . . . . GT:AD:DP ./.:0:0 chr1 11940 . A . . . . GT:AD:DP ./.:0:0 chr1 11941 . C . . . . GT:AD:DP ./.:0:0 chr1 11942 . T . . . . GT:AD:DP ./.:0:0 chr1 11943 . T . . . . GT:AD:DP ./.:0:0 chr1 11944 . C . . . . GT:AD:DP ./.:0:0 chr1 11945 . C . . . . GT:AD:DP ./.:0:0 chr1 11946 . C . . . . GT:AD:DP ./.:0:0 chr1 11947 . G . . . . GT:AD:DP ./.:0:0 chr1 11948 . T . . . . GT:AD:DP ./.:0:0 chr1 11949 . G . . . . GT:AD:DP ./.:0:0 chr1 11950 . T . . . . GT:AD:DP ./.:0:0 chr1 11951 . C . . . . GT:AD:DP ./.:0:0 chr1 11952 . C . . . . GT:AD:DP ./.:0:0 chr1 11953 . T . . . . GT:AD:DP ./.:0:0 chr1 11954 . T . . . . GT:AD:DP ./.:0:0 chr1 11955 . T . . . . GT:AD:DP ./.:0:0 chr1 11956 . C . . . . GT:AD:DP ./.:0:0 chr1 11957 . C . . . . GT:AD:DP ./.:0:0 chr1 11958 . A . . . . GT:AD:DP ./.:0:0 chr1 11959 . C . . . . GT:AD:DP ./.:0:0 chr1 11960 . C . . . . GT:AD:DP ./.:0:0 chr1 11961 . G . . . . GT:AD:DP ./.:0:0 chr1 11962 . G . . . . GT:AD:DP ./.:0:0 chr1 11963 . G . . . . GT:AD:DP ./.:0:0 chr1 11964 . C . . . . GT:AD:DP ./.:0:0 chr1 11965 . C . . . . GT:AD:DP ./.:0:0 chr1 11966 . T . . . . GT:AD:DP ./.:0:0 chr1 11967 . T . . . . GT:AD:DP ./.:0:0 chr1 11968 . T . . . . GT:AD:DP ./.:0:0 chr1 11969 . G . . . . GT:AD:DP ./.:0:0 chr1 11970 . A . . . . GT:AD:DP ./.:0:0 chr1 11971 . G . . . . GT:AD:DP ./.:0:0 chr1 11972 . A . . . . GT:AD:DP ./.:0:0 chr1 11973 . G . . . . GT:AD:DP ./.:0:0 chr1 11974 . G . . . . GT:AD:DP ./.:0:0 chr1 11975 . T . . . . GT:AD:DP ./.:0:0 chr1 11976 . C . . . . GT:AD:DP ./.:0:0 chr1 11977 . A . . . . GT:AD:DP ./.:0:0 chr1 11978 . C . . . . GT:AD:DP ./.:0:0 chr1 11979 . A . . . . GT:AD:DP ./.:0:0 chr1 11980 . G . . . . GT:AD:DP ./.:0:0 chr1 11981 . G . . . . GT:AD:DP ./.:0:0 chr1 11982 . G . . . . GT:AD:DP ./.:0:0 chr1 11983 . T . . . . GT:AD:DP ./.:0:0 chr1 11984 . C . . . . GT:AD:DP ./.:0:0 chr1 11985 . T . . . . GT:AD:DP ./.:0:0 chr1 11986 . T . . . . GT:AD:DP ./.:0:0 chr1 11987 . G . . . . GT:AD:DP ./.:0:0 chr1 11988 . A . . . . GT:AD:DP ./.:0:0 chr1 11989 . T . . . . GT:AD:DP ./.:0:0 chr1 11990 . G . . . . GT:AD:DP ./.:0:0 chr1 11991 . C . . . . GT:AD:DP ./.:0:0 chr1 11992 . T . . . . GT:AD:DP ./.:0:0 chr1 11993 . G . . . . GT:AD:DP ./.:0:0 chr1 11994 . T . . . . GT:AD:DP ./.:0:0 chr1 11995 . G . . . . GT:AD:DP ./.:0:0 chr1 11996 . G . . . . GT:AD:DP ./.:0:0 chr1 11997 . T . . . . GT:AD:DP ./.:0:0 chr1 11998 . C . . . . GT:AD:DP ./.:0:0 chr1 11999 . T . . . . GT:AD:DP ./.:0:0 chr1 12000 . T . . . . GT:AD:DP ./.:0:0 chr1 12001 . C . . . . GT:AD:DP ./.:0:0 chr1 12002 . A . . . . GT:AD:DP ./.:0:0 chr1 12003 . T . . . . GT:AD:DP ./.:0:0 chr1 12004 . C . . . . GT:AD:DP ./.:0:0 chr1 12005 . T . . . . GT:AD:DP ./.:0:0 chr1 12006 . G . . . . GT:AD:DP ./.:0:0 chr1 12007 . C . . . . GT:AD:DP ./.:0:0 chr1 12008 . A . . . . GT:AD:DP ./.:0:0 chr1 12009 . G . . . . GT:AD:DP ./.:0:0 chr1 12010 . G . . . . GT:AD:DP ./.:0:0 chr1 12011 . T . . . . GT:AD:DP ./.:0:0 chr1 12012 . G . . . . GT:AD:DP ./.:0:0 chr1 12013 . T . . . . GT:AD:DP ./.:0:0 chr1 12014 . C . . . . GT:AD:DP ./.:0:0 chr1 12015 . T . . . . GT:AD:DP ./.:0:0 chr1 12016 . G . . . . GT:AD:DP ./.:0:0 chr1 12017 . A . . . . GT:AD:DP ./.:0:0 chr1 12018 . C . . . . GT:AD:DP ./.:0:0 chr1 12019 . T . . . . GT:AD:DP ./.:0:0 chr1 12020 . T . . . . GT:AD:DP ./.:0:0 chr1 12021 . C . . . . GT:AD:DP ./.:0:0 chr1 12022 . C . . . . GT:AD:DP ./.:0:0 chr1 12023 . A . . . . GT:AD:DP ./.:0:0 chr1 12024 . G . . . . GT:AD:DP ./.:0:0 chr1 12025 . C . . . . GT:AD:DP ./.:0:0 chr1 12026 . A . . . . GT:AD:DP ./.:0:0 chr1 12027 . A . . . . GT:AD:DP ./.:0:0 chr1 12028 . C . . . . GT:AD:DP ./.:0:0 chr1 12029 . T . . . . GT:AD:DP ./.:0:0 chr1 12030 . G . . . . GT:AD:DP ./.:0:0 chr1 12031 . C . . . . GT:AD:DP ./.:0:0 chr1 12032 . T . . . . GT:AD:DP ./.:0:0 chr1 12033 . G . . . . GT:AD:DP ./.:0:0 chr1 12034 . G . . . . GT:AD:DP ./.:0:0 chr1 12035 . C . . . . GT:AD:DP ./.:0:0 chr1 12036 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12037 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12038 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12039 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12040 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12041 . C . . . . GT:AD:DP ./.:0:0 chr1 12042 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12043 . A . . . . GT:AD:DP ./.:0:0 chr1 12044 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12045 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12046 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12047 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12048 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12049 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 12050 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12051 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12052 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12053 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12054 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12055 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12056 . A . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12057 . G . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12058 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12059 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 12060 . C . . . DP=1 GT:AD:DP ./.:0:0 chr1 12061 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 12062 . G . . . DP=1 GT:AD:DP ./.:0:0 chr1 12063 . G . . . DP=1 GT:AD:DP ./.:0:0 chr1 12064 . A . . . DP=1 GT:AD:DP ./.:0:0 chr1 12065 . G . . . DP=1 GT:AD:DP ./.:0:0 chr1 12066 . T . . . DP=1 GT:AD:DP ./.:0:0 chr1 12067 . G . . . DP=1 GT:AD:DP ./.:0:0 chr1 12068 . G . . . DP=1 GT:AD:DP ./.:0:0 chr1 12069 . A . . . . GT:AD:DP ./.:0:0 chr1 12070 . G . . . . GT:AD:DP ./.:0:0 chr1 12071 . T . . . . GT:AD:DP ./.:0:0 chr1 12072 . T . . . . GT:AD:DP ./.:0:0 chr1 12073 . T . . . . GT:AD:DP ./.:0:0 chr1 12074 . T . . . . GT:AD:DP ./.:0:0 chr1 12075 . C . . . . GT:AD:DP ./.:0:0 chr1 12076 . C . . . . GT:AD:DP ./.:0:0 chr1 12077 . T . . . . GT:AD:DP ./.:0:0 chr1 12078 . G . . . . GT:AD:DP ./.:0:0 chr1 12079 . T . . . . GT:AD:DP ./.:0:0 chr1 12080 . G . . . . GT:AD:DP ./.:0:0 chr1 12081 . G . . . . GT:AD:DP ./.:0:0 chr1 12082 . A . . . . GT:AD:DP ./.:0:0 chr1 12083 . G . . . . GT:AD:DP ./.:0:0 chr1 12084 . A . . . . GT:AD:DP ./.:0:0 chr1 12085 . G . . . . GT:AD:DP ./.:0:0 chr1 12086 . G . . . . GT:AD:DP ./.:0:0 chr1 12087 . A . . . . GT:AD:DP ./.:0:0 chr1 12088 . G . . . . GT:AD:DP ./.:0:0 chr1 12089 . C . . . . GT:AD:DP ./.:0:0 chr1 12090 . C . . . . GT:AD:DP ./.:0:0 chr1 12091 . A . . . . GT:AD:DP ./.:0:0 chr1 12092 . T . . . . GT:AD:DP ./.:0:0 chr1 12093 . G . . . . GT:AD:DP ./.:0:0 chr1 12094 . C . . . . GT:AD:DP ./.:0:0 chr1 12095 . C . . . . GT:AD:DP ./.:0:0 chr1 12096 . T . . . . GT:AD:DP ./.:0:0 chr1 12097 . A . . . . GT:AD:DP ./.:0:0 chr1 12098 . G . . . . GT:AD:DP ./.:0:0 chr1 12099 . A . . . . GT:AD:DP ./.:0:0 chr1 12100 . G . . . . GT:AD:DP ./.:0:0 chr1 12101 . T . . . . GT:AD:DP ./.:0:0 chr1 12102 . G . . . . GT:AD:DP ./.:0:0 chr1 12103 . G . . . . GT:AD:DP ./.:0:0 chr1 12104 . G . . . . GT:AD:DP ./.:0:0 chr1 12105 . A . . . . GT:AD:DP ./.:0:0 chr1 12106 . T . . . . GT:AD:DP ./.:0:0 chr1 12107 . G . . . . GT:AD:DP ./.:0:0 chr1 12108 . G . . . . GT:AD:DP ./.:0:0 chr1 12109 . G . . . . GT:AD:DP ./.:0:0 chr1 12110 . C . . . . GT:AD:DP ./.:0:0 chr1 12111 . C . . . . GT:AD:DP ./.:0:0 chr1 12112 . A . . . . GT:AD:DP ./.:0:0 chr1 12113 . T . . . . GT:AD:DP ./.:0:0 chr1 12114 . T . . . . GT:AD:DP ./.:0:0 chr1 12115 . G . . . . GT:AD:DP ./.:0:0 chr1 12116 . T . . . . GT:AD:DP ./.:0:0 chr1 12117 . T . . . . GT:AD:DP ./.:0:0 chr1 12118 . C . . . . GT:AD:DP ./.:0:0 chr1 12119 . A . . . . GT:AD:DP ./.:0:0 chr1 12120 . T . . . . GT:AD:DP ./.:0:0 chr1 12121 . C . . . . GT:AD:DP ./.:0:0 chr1 12122 . T . . . . GT:AD:DP ./.:0:0 chr1 12123 . T . . . . GT:AD:DP ./.:0:0 chr1 12124 . C . . . . GT:AD:DP ./.:0:0 chr1 12125 . T . . . . GT:AD:DP ./.:0:0 chr1 12126 . G . . . . GT:AD:DP ./.:0:0 chr1 12127 . G . . . . GT:AD:DP ./.:0:0 chr1 12128 . C . . . . GT:AD:DP ./.:0:0 chr1 12129 . C . . . . GT:AD:DP ./.:0:0 chr1 12130 . C . . . . GT:AD:DP ./.:0:0 chr1 12131 . C . . . . GT:AD:DP ./.:0:0 chr1 12132 . T . . . . GT:AD:DP ./.:0:0 chr1 12133 . G . . . . GT:AD:DP ./.:0:0 chr1 12134 . T . . . . GT:AD:DP ./.:0:0 chr1 12135 . T . . . . GT:AD:DP ./.:0:0 chr1 12136 . G . . . . GT:AD:DP ./.:0:0 chr1 12137 . T . . . . GT:AD:DP ./.:0:0 chr1 12138 . C . . . . GT:AD:DP ./.:0:0 chr1 12139 . T . . . . GT:AD:DP ./.:0:0 chr1 12140 . G . . . . GT:AD:DP ./.:0:0 chr1 12141 . C . . . . GT:AD:DP ./.:0:0 chr1 12142 . A . . . . GT:AD:DP ./.:0:0 chr1 12143 . T . . . . GT:AD:DP ./.:0:0 chr1 12144 . G . . . . GT:AD:DP ./.:0:0 chr1 12145 . T . . . . GT:AD:DP ./.:0:0 chr1 12146 . A . . . . GT:AD:DP ./.:0:0 chr1 12147 . A . . . . GT:AD:DP ./.:0:0 chr1 12148 . C . . . . GT:AD:DP ./.:0:0 chr1 12149 . T . . . . GT:AD:DP ./.:0:0 chr1 12150 . T . . . . GT:AD:DP ./.:0:0 chr1 12151 . A . . . . GT:AD:DP ./.:0:0 chr1 12152 . A . . . . GT:AD:DP ./.:0:0 chr1 12153 . T . . . . GT:AD:DP ./.:0:0 chr1 12154 . A . . . . GT:AD:DP ./.:0:0 chr1 12155 . C . . . . GT:AD:DP ./.:0:0 chr1 12156 . C . . . . GT:AD:DP ./.:0:0 chr1 12157 . A . . . . GT:AD:DP ./.:0:0 chr1 12158 . C . . . . GT:AD:DP ./.:0:0 chr1 12159 . A . . . . GT:AD:DP ./.:0:0 chr1 12160 . A . . . . GT:AD:DP ./.:0:0 chr1 12161 . C . . . . GT:AD:DP ./.:0:0 chr1 12162 . C . . . . GT:AD:DP ./.:0:0 chr1 12163 . A . . . . GT:AD:DP ./.:0:0 chr1 12164 . G . . . . GT:AD:DP ./.:0:0 chr1 12165 . G . . . . GT:AD:DP ./.:0:0 chr1 12166 . C . . . . GT:AD:DP ./.:0:0 chr1 12167 . A . . . . GT:AD:DP ./.:0:0 chr1 12168 . T . . . . GT:AD:DP ./.:0:0 chr1 12169 . A . . . . GT:AD:DP ./.:0:0 chr1 12170 . G . . . . GT:AD:DP ./.:0:0 chr1 12171 . G . . . . GT:AD:DP ./.:0:0 chr1 12172 . G . . . . GT:AD:DP ./.:0:0 chr1 12173 . G . . . . GT:AD:DP ./.:0:0 chr1 12174 . A . . . . GT:AD:DP ./.:0:0 chr1 12175 . A . . . . GT:AD:DP ./.:0:0 chr1 12176 . A . . . . GT:AD:DP ./.:0:0 chr1 12177 . G . . . . GT:AD:DP ./.:0:0 chr1 12178 . A . . . . GT:AD:DP ./.:0:0 chr1 12179 . T . . . . GT:AD:DP ./.:0:0 chr1 12180 . T . . . . GT:AD:DP ./.:0:0 chr1 12181 . G . . . . GT:AD:DP ./.:0:0 chr1 12182 . G . . . . GT:AD:DP ./.:0:0 chr1 12183 . A . . . . GT:AD:DP ./.:0:0 chr1 12184 . G . . . . GT:AD:DP ./.:0:0 chr1 12185 . G . . . . GT:AD:DP ./.:0:0 chr1 12186 . A . . . . GT:AD:DP ./.:0:0 chr1 12187 . A . . . . GT:AD:DP ./.:0:0 chr1 12188 . A . . . . GT:AD:DP ./.:0:0 chr1 12189 . G . . . . GT:AD:DP ./.:0:0 chr1 12190 . A . . . . GT:AD:DP ./.:0:0 chr1 12191 . T . . . . GT:AD:DP ./.:0:0 chr1 12192 . G . . . . GT:AD:DP ./.:0:0 chr1 12193 . A . . . . GT:AD:DP ./.:0:0 chr1 12194 . G . . . . GT:AD:DP ./.:0:0 chr1 12195 . T . . . . GT:AD:DP ./.:0:0 chr1 12196 . G . . . . GT:AD:DP ./.:0:0 chr1 12197 . A . . . . GT:AD:DP ./.:0:0 chr1 12198 . G . . . . GT:AD:DP ./.:0:0 chr1 12199 . A . . . . GT:AD:DP ./.:0:0 chr1 12200 . G . . . . GT:AD:DP ./.:0:0 chr1 12201 . C . . . . GT:AD:DP ./.:0:0 chr1 12202 . A . . . . GT:AD:DP ./.:0:0 chr1 12203 . T . . . . GT:AD:DP ./.:0:0 chr1 12204 . C . . . . GT:AD:DP ./.:0:0 chr1 12205 . A . . . . GT:AD:DP ./.:0:0 chr1 12206 . A . . . . GT:AD:DP ./.:0:0 chr1 12207 . C . . . . GT:AD:DP ./.:0:0 chr1 12208 . T . . . . GT:AD:DP ./.:0:0 chr1 12209 . T . . . . GT:AD:DP ./.:0:0 chr1 12210 . C . . . . GT:AD:DP ./.:0:0 chr1 12211 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12212 . C . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12213 . T . . . AN=2;DP=1 GT:AD:DP ./.:0:0 chr1 12214 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12215 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12216 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12217 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12218 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12219 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12220 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12221 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12222 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12223 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12224 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12225 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12226 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12227 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12228 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12229 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12230 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12231 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12232 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12233 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12234 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12235 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12236 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12237 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12238 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12239 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12240 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12241 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12242 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12243 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12244 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12245 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12246 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12247 . A . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12248 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12249 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12250 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12251 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12252 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12253 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12254 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12255 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12256 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12257 . C . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12258 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12259 . G . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12260 . T . . . AN=4;DP=2 GT:AD:DP ./.:0:0 chr1 12261 . G . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 12262 . A . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 12263 . T . . . AN=6;DP=3 GT:AD:DP ./.:0:0 chr1 12264 . A . . . AN=8;DP=4 GT:AD:DP ./.:0:0 chr1 12265 . C . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12266 . G . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12267 . T . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12268 . G . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12269 . G . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12270 . C . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12271 . C . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12272 . G . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12273 . G . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12274 . C . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12275 . C . . . AN=10;DP=5 GT:AD:DP ./.:0:0 chr1 12276 . C . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12277 . T . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12278 . C . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12279 . G . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12280 . C . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12281 . T . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12282 . C . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12283 . C . . . AN=12;DP=6 GT:AD:DP ./.:0:0 chr1 12284 . A . . . AN=12;DP=7 GT:AD:DP ./.:0:0 chr1 12285 . G . . . AN=14;DP=7 GT:AD:DP ./.:0:0 chr1 12286 . C . . . AN=16;DP=8 GT:AD:DP ./.:0:0 chr1 12287 . A . . . AN=14;DP=9 GT:AD:DP ./.:0:0 chr1 12288 . G . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12289 . C . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12290 . T . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12291 . G . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12292 . G . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12293 . A . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12294 . C . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12295 . C . . . AN=16;DP=9 GT:AD:DP ./.:0:0 chr1 12296 . C . . . AN=20;DP=11 GT:AD:DP ./.:0:0 chr1 12297 . C . . . AN=20;DP=11 GT:AD:DP ./.:0:0 chr1 12298 . T . . . AN=22;DP=12 GT:AD:DP ./.:0:0 chr1 12299 . A . . . AN=20;DP=12 GT:AD:DP ./.:0:0 chr1 12300 . C . . . AN=22;DP=12 GT:AD:DP ./.:0:0 chr1 12301 . C . . . AN=22;DP=12 GT:AD:DP ./.:0:0 chr1 12302 . T . . . AN=22;DP=13 GT:AD:DP ./.:0:0 chr1 12303 . G . . . AN=24;DP=13 GT:AD:DP ./.:0:0 chr1 12304 . C . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 12305 . C . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 12306 . G . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 12307 . T . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 12308 . C . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 12309 . T . . . AN=24;DP=14 GT:AD:DP ./.:0:0 chr1 12310 . G . . . AN=26;DP=14 GT:AD:DP ./.:0:0 chr1 12311 . C . . . AN=28;DP=15 GT:AD:DP ./.:0:0 chr1 12312 . T . . . AN=28;DP=15 GT:AD:DP ./.:0:0 chr1 12313 . G . . . AN=28;DP=15 GT:AD:DP ./.:0:0 chr1 12314 . C . . . AN=28;DP=15 GT:AD:DP ./.:0:0 chr1 12315 . C . . . AN=28;DP=15 GT:AD:DP ./.:0:0 chr1 12316 . A . . . AN=28;DP=15 GT:AD:DP ./.:0:0 chr1 12317 . T . . . AN=26;DP=16 GT:AD:DP ./.:0:0 chr1 12318 . C . . . AN=28;DP=16 GT:AD:DP ./.:0:0 chr1 12319 . G . . . AN=28;DP=16 GT:AD:DP ./.:0:0 chr1 12320 . G . . . AN=28;DP=16 GT:AD:DP ./.:0:0 chr1 12321 . A . . . AN=30;DP=17 GT:AD:DP ./.:0:0 chr1 12322 . G . . . AN=30;DP=17 GT:AD:DP ./.:0:0 chr1 12323 . C . . . AN=30;DP=17 GT:AD:DP ./.:0:0 chr1 12324 . C . . . AN=30;DP=17 GT:AD:DP ./.:0:0 chr1 12325 . C . . . AN=30;DP=17 GT:AD:DP ./.:0:0 chr1 12326 . A . . . AN=32;DP=18 GT:AD:DP ./.:0:0 chr1 12327 . A . . . AN=32;DP=19 GT:AD:DP ./.:0:0 chr1 12328 . A . . . AN=34;DP=19 GT:AD:DP ./.:0:0 chr1 12329 . G . . . AN=36;DP=20 GT:AD:DP ./.:0:0 chr1 12330 . C . . . AN=38;DP=21 GT:AD:DP ./.:0:0 chr1 12331 . C . . . AN=38;DP=21 GT:AD:DP ./.:0:0 chr1 12332 . G . . . AN=34;DP=21 GT:AD:DP ./.:0:0 chr1 12333 . G . . . AN=38;DP=21 GT:AD:DP ./.:0:0 chr1 12334 . G . . . AN=38;DP=21 GT:AD:DP ./.:0:0 chr1 12335 . C . . . AN=38;DP=21 GT:AD:DP ./.:0:0 chr1 12336 . T . . . AN=40;DP=22 GT:AD:DP ./.:0:0 chr1 12337 . G . . . AN=42;DP=23 GT:AD:DP ./.:0:0 chr1 12338 . T . . . AN=38;DP=23 GT:AD:DP ./.:0:0 chr1 12339 . G . . . AN=40;DP=23 GT:AD:DP ./.:0:0 chr1 12340 . A . . . AN=38;DP=24 GT:AD:DP ./.:0:0 chr1 12341 . C . . . AN=44;DP=24 GT:AD:DP ./.:0:0 chr1 12342 . T . . . AN=44;DP=24 GT:AD:DP ./.:0:0 chr1 12343 . G . . . AN=48;DP=26 GT:AD:DP ./.:0:0 chr1 12344 . C . . . AN=50;DP=27 GT:AD:DP ./.:0:0 chr1 12345 . T . . . AN=48;DP=27 GT:AD:DP ./.:0:0 chr1 12346 . C . . . AN=50;DP=27 GT:AD:DP ./.:0:0 chr1 12347 . A . . . AN=50;DP=27 GT:AD:DP ./.:0:0 chr1 12348 . G . . . AN=50;DP=28 GT:AD:DP ./.:0:0 chr1 12349 . A . . . AN=50;DP=28 GT:AD:DP ./.:0:0 chr1 12350 . C . . . AN=52;DP=28 GT:AD:DP ./.:0:0 chr1 12351 . C . . . AN=52;DP=28 GT:AD:DP ./.:0:0 chr1 12352 . A . . . AN=50;DP=29 GT:AD:DP ./.:0:0 chr1 12353 . G . . . AN=50;DP=29 GT:AD:DP ./.:0:0 chr1 12354 . C . . . AN=50;DP=29 GT:AD:DP ./.:0:0 chr1 12355 . C . . . AN=52;DP=30 GT:AD:DP ./.:0:0 chr1 12356 . G . . . AN=52;DP=30 GT:AD:DP ./.:0:0 chr1 12357 . G . . . AN=52;DP=30 GT:AD:DP ./.:0:0 chr1 12358 . C . . . AN=52;DP=30 GT:AD:DP ./.:0:0 chr1 12359 . T . . . AN=52;DP=31 GT:AD:DP ./.:0:0 chr1 12360 . G . . . AN=54;DP=31 GT:AD:DP ./.:0:0 chr1 12361 . G . . . AN=58;DP=33 GT:AD:DP ./.:0:0 chr1 12362 . A . . . AN=58;DP=32 GT:AD:DP ./.:0:0 chr1 12363 . G . . . AN=58;DP=32 GT:AD:DP ./.:0:0 chr1 12364 . G . . . AN=60;DP=33 GT:AD:DP ./.:0:0 chr1 12365 . G . . . AN=60;DP=32 GT:AD:DP ./.:0:0 chr1 12366 . A . . . AN=56;DP=33 GT:AD:DP ./.:0:0 chr1 12367 . G . . . AN=62;DP=33 GT:AD:DP ./.:0:0 chr1 12368 . G . . . AN=62;DP=33 GT:AD:DP ./.:0:0 chr1 12369 . G . . . AN=62;DP=33 GT:AD:DP ./.:0:0 chr1 12370 . G . . . AN=64;DP=34 GT:AD:DP ./.:0:0 chr1 12371 . C . . . AN=66;DP=36 GT:AD:DP ./.:0:0 chr1 12372 . T . . . AN=64;DP=37 GT:AD:DP ./.:0:0 chr1 12373 . C . . . AN=68;DP=37 GT:AD:DP ./.:0:0 chr1 12374 . A . . . AN=66;DP=38 GT:AD:DP ./.:0:0 chr1 12375 . G . . . AN=72;DP=39 GT:AD:DP ./.:0:0 chr1 12376 . C . . . AN=74;DP=40 GT:AD:DP ./.:0:0 chr1 12377 . A . . . AN=76;DP=43 GT:AD:DP ./.:0:0 chr1 12378 . G . . . AN=78;DP=43 GT:AD:DP ./.:0:0 chr1 12379 . G . . . AN=78;DP=43 GT:AD:DP ./.:0:0 chr1 12380 . T . . . AN=76;DP=44 GT:AD:DP ./.:0:0 chr1 12381 . C . . . AN=80;DP=44 GT:AD:DP ./.:0:0 chr1 12382 . T . . . AN=78;DP=44 GT:AD:DP ./.:0:0 chr1 12383 . G . . . AN=76;DP=44 GT:AD:DP ./.:0:0 chr1 12384 . G . . . AN=80;DP=44 GT:AD:DP ./.:0:0 chr1 12385 . C . . . AN=82;DP=45 GT:AD:DP ./.:0:0 chr1 12386 . T . . . AN=76;DP=45 GT:AD:DP ./.:0:0 chr1 12387 . T . . . AN=82;DP=46 GT:AD:DP ./.:0:0 chr1 12388 . T . . . AN=84;DP=46 GT:AD:DP ./.:0:0 chr1 12389 . G . . . AN=84;DP=46 GT:AD:DP ./.:0:0 chr1 12390 . G . . . AN=84;DP=46 GT:AD:DP ./.:0:0 chr1 12391 . C . . . AN=84;DP=46 GT:AD:DP ./.:0:0 chr1 12392 . C . . . AN=84;DP=46 GT:AD:DP ./.:0:0 chr1 12393 . C . . . AN=82;DP=46 GT:AD:DP ./.:0:0 chr1 12394 . T . . . AN=78;DP=46 GT:AD:DP ./.:0:0 chr1 12395 . G . . . AN=84;DP=46 GT:AD:DP ./.:0:0 chr1 12396 . G . . . AN=82;DP=46 GT:AD:DP ./.:0:0 chr1 12397 . G . . . AN=86;DP=47 GT:AD:DP ./.:0:0 chr1 12398 . A . . . AN=72;DP=47 GT:AD:DP ./.:0:0 chr1 12399 . G . . . AN=88;DP=48 GT:AD:DP ./.:0:0 chr1 12400 . A . . . AN=76;DP=48 GT:AD:DP ./.:0:0 chr1 12401 . G . . . AN=88;DP=49 GT:AD:DP ./.:0:0 chr1 12402 . C . . . AN=90;DP=49 GT:AD:DP ./.:0:0 chr1 12403 . A . . . AN=86;DP=49 GT:AD:DP ./.:0:0 chr1 12404 . G . . . AN=88;DP=49 GT:AD:DP ./.:0:0 chr1 12405 . G . . . AN=88;DP=50 GT:AD:DP ./.:0:0 chr1 12406 . T . . . AN=72;DP=50 GT:AD:DP ./.:0:0 chr1 12407 . G . . . AN=86;DP=50 GT:AD:DP ./.:0:0 chr1 12408 . G . . . AN=84;DP=50 GT:AD:DP ./.:0:0 chr1 12409 . A . . . AN=72;DP=50 GT:AD:DP ./.:0:0 chr1 12410 . A . . . AN=74;DP=50 GT:AD:DP ./.:0:0 chr1 12411 . G . . . AN=84;DP=50 GT:AD:DP ./.:0:0 chr1 12412 . A . . . AN=76;DP=50 GT:AD:DP ./.:0:0 chr1 12413 . T . . . AN=72;DP=50 GT:AD:DP ./.:0:0 chr1 12414 . C . . . AN=84;DP=51 GT:AD:DP ./.:0:0 chr1 12415 . A . . . AN=86;DP=52 GT:AD:DP ./.:0:0 chr1 12416 . G . . . AN=88;DP=53 GT:AD:DP ./.:0:0 chr1 12417 . G . . . AN=90;DP=53 GT:AD:DP ./.:0:0 chr1 12418 . C . . . AN=88;DP=53 GT:AD:DP ./.:0:0 chr1 12419 . A . . . AN=88;DP=54 GT:AD:DP ./.:0:0 chr1 12420 . G . . . AN=92;DP=55 GT:AD:DP ./.:0:0 chr1 12421 . G . . . AN=94;DP=56 GT:AD:DP ./.:0:0 chr1 12422 . C . . . AN=96;DP=57 GT:AD:DP ./.:0:0 chr1 12423 . C . . . AN=98;DP=58 GT:AD:DP ./.:0:0 chr1 12424 . A . . . AN=98;DP=61 GT:AD:DP ./.:0:0 chr1 12425 . T . . . AN=94;DP=62 GT:AD:DP ./.:0:0 chr1 12426 . C . . . AN=100;DP=62 GT:AD:DP ./.:0:0 chr1 12427 . G . . . AN=102;DP=63 GT:AD:DP ./.:0:0 chr1 12428 . C . . . AN=102;DP=63 GT:AD:DP ./.:0:0 chr1 12429 . T . . . AN=102;DP=64 GT:AD:DP ./.:0:0 chr1 12430 . G . . . AN=102;DP=64 GT:AD:DP ./.:0:0 chr1 12431 . C . . . AN=106;DP=65 GT:AD:DP ./.:0:0 chr1 12432 . C . . . AN=110;DP=67 GT:AD:DP ./.:0:0 chr1 12433 . A . . . AN=108;DP=68 GT:AD:DP ./.:0:0 chr1 12434 . C . . . AN=112;DP=68 GT:AD:DP ./.:0:0 chr1 12435 . A . . . AN=112;DP=68 GT:AD:DP ./.:0:0 chr1 12436 . G . . . AN=112;DP=68 GT:AD:DP ./.:0:0 chr1 12437 . A . . . AN=108;DP=68 GT:AD:DP ./.:0:0 chr1 12438 . A . . . AN=110;DP=68 GT:AD:DP ./.:0:0 chr1 12439 . C . . . AN=114;DP=70 GT:AD:DP ./.:0:0 chr1 12440 . C . . . AN=114;DP=70 GT:AD:DP ./.:0:0 chr1 12441 . C . . . AN=114;DP=71 GT:AD:DP ./.:0:0 chr1 12442 . A . . . AN=108;DP=71 GT:AD:DP ./.:0:0 chr1 12443 . G . . . AN=116;DP=72 GT:AD:DP ./.:0:0 chr1 12444 . T . . . AN=104;DP=72 GT:AD:DP ./.:0:0 chr1 12445 . G . . . AN=114;DP=73 GT:AD:DP ./.:0:0 chr1 12446 . G . . . AN=116;DP=73 GT:AD:DP ./.:0:0 chr1 12447 . A . . . AN=116;DP=73 GT:AD:DP ./.:0:0 chr1 12448 . T . . . AN=114;DP=74 GT:AD:DP ./.:0:0 chr1 12449 . T . . . AN=118;DP=74 GT:AD:DP ./.:0:0 chr1 12450 . G . . . AN=118;DP=75 GT:AD:DP ./.:0:0 chr1 12451 . G . . . AN=122;DP=75 GT:AD:DP ./.:0:0 chr1 12452 . C . . . AN=120;DP=75 GT:AD:DP ./.:0:0 chr1 12453 . C . . . AN=124;DP=75 GT:AD:DP ./.:0:0 chr1 12454 . T . . . AN=124;DP=76 GT:AD:DP ./.:0:0 chr1 12455 . A . . . AN=120;DP=75 GT:AD:DP ./.:0:0 chr1 12456 . G . . . AN=128;DP=76 GT:AD:DP ./.:0:0 chr1 12457 . G . . . AN=126;DP=78 GT:AD:DP ./.:0:0 chr1 12458 . T . . . AN=126;DP=79 GT:AD:DP ./.:0:0 chr1 12459 . G . . . AN=134;DP=79 GT:AD:DP ./.:0:0 chr1 12460 . G . . . AN=136;DP=81 GT:AD:DP ./.:0:0 chr1 12461 . G . . . AN=140;DP=83 GT:AD:DP ./.:0:0 chr1 12462 . A . . . AN=134;DP=84 GT:AD:DP ./.:0:0 chr1 12463 . T . . . AN=140;DP=84 GT:AD:DP ./.:0:0 chr1 12464 . C . . . AN=144;DP=85 GT:AD:DP ./.:0:0 chr1 12465 . T . . . AN=136;DP=85 GT:AD:DP ./.:0:0 chr1 12466 . C . . . AN=148;DP=87 GT:AD:DP ./.:0:0 chr1 12467 . T . . . AN=148;DP=88 GT:AD:DP ./.:0:0 chr1 12468 . G . . . AN=142;DP=87 GT:AD:DP ./.:0:0 chr1 12469 . A . . . AN=148;DP=89 GT:AD:DP ./.:0:0 chr1 12470 . G . . . AN=146;DP=90 GT:AD:DP ./.:0:0 chr1 12471 . C . . . AN=150;DP=91 GT:AD:DP ./.:0:0 chr1 12472 . T . . . AN=142;DP=90 GT:AD:DP ./.:0:0 chr1 12473 . C . . . AN=150;DP=91 GT:AD:DP ./.:0:0 chr1 12474 . A . . . AN=152;DP=92 GT:AD:DP ./.:0:0 chr1 12475 . A . . . AN=152;DP=92 GT:AD:DP ./.:0:0 chr1 12476 . C . . . AN=156;DP=93 GT:AD:DP ./.:0:0 chr1 12477 . A . . . AN=156;DP=93 GT:AD:DP ./.:0:0 chr1 12478 . A . . . AN=154;DP=94 GT:AD:DP ./.:0:0 chr1 12479 . G . . . AN=162;DP=95 GT:AD:DP ./.:0:0 chr1 12480 . C . . . AN=160;DP=94 GT:AD:DP ./.:0:0 chr1 12481 . C . . . AN=166;DP=95 GT:AD:DP ./.:0:0 chr1 12482 . C . . . AN=166;DP=98 GT:AD:DP ./.:0:0 chr1 12483 . T . . . AN=172;DP=101 GT:AD:DP ./.:0:0 chr1 12484 . C . . . AN=178;DP=105 GT:AD:DP ./.:0:0 chr1 12485 . T . . . AN=174;DP=108 GT:AD:DP ./.:0:0 chr1 12486 . C . . . AN=190;DP=113 GT:AD:DP ./.:0:0 chr1 12487 . T . . . AN=186;DP=114 GT:AD:DP ./.:0:0 chr1 12488 . G . . . AN=192;DP=114 GT:AD:DP ./.:0:0 chr1 12489 . G . . . AN=196;DP=119 GT:AD:DP ./.:0:0 chr1 12490 . G . . . AN=202;DP=122 GT:AD:DP ./.:0:0 chr1 12491 . T . . . AN=188;DP=122 GT:AD:DP ./.:0:0 chr1 12492 . G . . . AN=208;DP=125 GT:AD:DP ./.:0:0 chr1 12493 . G . . . AN=212;DP=127 GT:AD:DP ./.:0:0 chr1 12494 . T . . . AN=192;DP=125 GT:AD:DP ./.:0:0 chr1 12495 . A . . . AN=204;DP=126 GT:AD:DP ./.:0:0 chr1 12496 . G . . . AN=212;DP=128 GT:AD:DP ./.:0:0 chr1 12497 . G . . . AN=218;DP=131 GT:AD:DP ./.:0:0 chr1 12498 . T . . . AN=218;DP=133 GT:AD:DP ./.:0:0 chr1 12499 . G . . . AN=218;DP=134 GT:AD:DP ./.:0:0 chr1 12500 . C . . . AN=224;DP=136 GT:AD:DP ./.:0:0 chr1 12501 . A . . . AN=224;DP=139 GT:AD:DP ./.:0:0 chr1 12502 . G . . . AN=236;DP=142 GT:AD:DP ./.:0:0 chr1 12503 . A . . . AN=234;DP=144 GT:AD:DP ./.:0:0 chr1 12504 . G . . . AN=240;DP=146 GT:AD:DP ./.:0:0 chr1 12505 . A . . . AN=240;DP=148 GT:AD:DP ./.:0:0 chr1 12506 . C . . . AN=246;DP=150 GT:AD:DP ./.:0:0 chr1 12507 . G . . . AN=258;DP=157 GT:AD:DP ./.:0:0 chr1 12508 . G . . . AN=264;DP=159 GT:AD:DP ./.:0:0 chr1 12509 . G . . . AN=270;DP=163 GT:AD:DP ./.:0:0 chr1 12510 . A . . . AN=264;DP=164 GT:AD:DP ./.:0:0 chr1 12511 . G . . . AN=274;DP=167 GT:AD:DP ./.:0:0 chr1 12512 . G . . . AN=278;DP=171 GT:AD:DP ./.:0:0 chr1 12513 . G . . . AN=274;DP=171 GT:AD:DP ./.:0:0 chr1 12514 . G . . . AN=280;DP=176 GT:AD:DP ./.:0:0 chr1 12515 . C . . . AN=280;DP=178 GT:AD:DP ./.:0:0 chr1 12516 . A . . . AN=284;DP=181 GT:AD:DP ./.:0:0 chr1 12517 . G . . . AN=292;DP=185 GT:AD:DP ./.:0:0 chr1 12518 . A . . . AN=302;DP=191 GT:AD:DP ./.:0:0 chr1 12519 . G . . . AN=308;DP=195 GT:AD:DP ./.:0:0 chr1 12520 . C . . . AN=312;DP=200 GT:AD:DP ./.:0:0 chr1 12521 . C . . . AN=314;DP=204 GT:AD:DP ./.:0:0 chr1 12522 . G . . . AN=326;DP=212 GT:AD:DP ./.:0:0 chr1 12523 . C . . . AN=344;DP=220 GT:AD:DP ./.:0:0 chr1 12524 . A . . . AN=342;DP=222 GT:AD:DP ./.:0:0 chr1 12525 . G . . . AN=354;DP=226 GT:AD:DP ./.:0:0 chr1 12526 . G . . . AN=352;DP=225 GT:AD:DP ./.:0:0 chr1 12527 . C . . . AN=360;DP=230 GT:AD:DP ./.:0:0 chr1 12528 . A . . . AN=352;DP=233 GT:AD:DP ./.:0:0 chr1 12529 . C . . . AN=374;DP=237 GT:AD:DP ./.:0:0 chr1 12530 . A . . . AN=372;DP=243 GT:AD:DP ./.:0:0 chr1 12531 . G . . . AN=384;DP=250 GT:AD:DP ./.:0:0 chr1 12532 . C . . . AN=388;DP=255 GT:AD:DP ./.:0:0 chr1 12533 . C . . . AN=390;DP=261 GT:AD:DP ./.:0:0 chr1 12534 . A . . . AN=396;DP=268 GT:AD:DP ./.:0:0 chr1 12535 . A . . . AN=400;DP=271 GT:AD:DP ./.:0:0 chr1 12536 . G . . . AN=420;DP=278 GT:AD:DP ./.:0:0 chr1 12537 . A . . . AN=422;DP=281 GT:AD:DP ./.:0:0 chr1 12538 . G . . . AN=428;DP=282 GT:AD:DP ./.:0:0 chr1 12539 . G . . . AN=434;DP=286 GT:AD:DP ./.:0:0 chr1 12540 . G . . . AN=426;DP=288 GT:AD:DP ./.:0:0 chr1 12541 . C . . . AN=436;DP=295 GT:AD:DP ./.:0:0 chr1 12542 . T . . . AN=432;DP=303 GT:AD:DP ./.:0:0 chr1 12543 . G . . . AN=460;DP=310 GT:AD:DP ./.:0:0 chr1 12544 . A . . . AN=466;DP=322 GT:AD:DP ./.:0:0 chr1 12545 . A C . . AC=0;AF=0;AN=470;DP=325;ExcessHet=3.01;MQ=1.11 GT:AD:DP:PGT:PID ./.:0,0:0:.:. chr1 12546 . G . . . AN=480;DP=330 GT:AD:DP ./.:0:0 chr1 12547 . A C . . AC=0;AF=0;AN=490;DP=337;ExcessHet=3.01;MQ=1.09 GT:AD:DP:PGT:PID ./.:0,0:0:.:. chr1 12548 . A . . . AN=496;DP=344 GT:AD:DP ./.:0:0 chr1 12549 . A . . . AN=500;DP=353 GT:AD:DP ./.:0:0 chr1 12550 . T . . . AN=490;DP=354 GT:AD:DP ./.:0:0 chr1 12551 . G . . . AN=510;DP=356 GT:AD:DP ./.:0:0 chr1 12552 . G . . . AN=516;DP=363 GT:AD:DP ./.:0:0 chr1 12553 . T . . . AN=510;DP=370 GT:AD:DP ./.:0:0 chr1 12554 . A . . . AN=514;DP=373 GT:AD:DP ./.:0:0 chr1 12555 . G . . . AN=526;DP=376 GT:AD:DP ./.:0:0 chr1 12556 . A . . . AN=536;DP=382 GT:AD:DP ./.:0:0 chr1 12557 . A . . . AN=538;DP=387 GT:AD:DP ./.:0:0 chr1 12558 . C . . . AN=546;DP=396 GT:AD:DP ./.:0:0 chr1 12559 . G . . . AN=560;DP=406 GT:AD:DP ./.:0:0 chr1 12560 . G . . . AN=572;DP=418 GT:AD:DP ./.:0:0 chr1 12561 . A . . . AN=560;DP=430 GT:AD:DP ./.:0:0 chr1 12562 . G . . . AN=588;DP=438 GT:AD:DP ./.:0:0 chr1 12563 . C . . . AN=598;DP=448 GT:AD:DP ./.:0:0 chr1 12564 . A . . . AN=586;DP=457 GT:AD:DP ./.:0:0 chr1 12565 . G . . . AN=612;DP=465 GT:AD:DP ./.:0:0 chr1 12566 . C . . . AN=616;DP=472 GT:AD:DP ./.:0:0 chr1 12567 . T . . . AN=608;DP=485 GT:AD:DP ./.:0:0 chr1 12568 . G . . . AN=628;DP=492 GT:AD:DP ./.:0:0 chr1 12569 . G . . . AN=636;DP=500 GT:AD:DP ./.:0:0 chr1 12570 . T . . . AN=618;DP=504 GT:AD:DP ./.:0:0 chr1 12571 . G . . . AN=644;DP=511 GT:AD:DP ./.:0:0 chr1 12572 . A . . . AN=626;DP=517 GT:AD:DP ./.:0:0 chr1 12573 . T . . . AN=622;DP=520 GT:AD:DP ./.:0:0 chr1 12574 . G . . . AN=648;DP=526 GT:AD:DP ./.:0:0 chr1 12575 . T . . . AN=640;DP=533 GT:AD:DP ./.:0:0 chr1 12576 . G . . . AN=666;DP=536 GT:AD:DP ./.:0:0 chr1 12577 . T . . . AN=668;DP=545 GT:AD:DP ./.:0:0 chr1 12578 . G . . . AN=676;DP=546 GT:AD:DP ./.:0:0 chr1 12579 . G . . . AN=676;DP=552 GT:AD:DP ./.:0:0 chr1 12580 . G . . . AN=692;DP=559 GT:AD:DP ./.:0:0 chr1 12581 . C . . . AN=690;DP=567 GT:AD:DP ./.:0:0 chr1 12582 . C . . . AN=700;DP=575 GT:AD:DP ./.:0:0 chr1 12583 . C . . . AN=716;DP=584 GT:AD:DP ./.:0:0 chr1 12584 . A . . . AN=714;DP=594 GT:AD:DP ./.:0:0 chr1 12585 . C . . . AN=722;DP=603 GT:AD:DP ./.:0:0 chr1 12586 . C . . . AN=734;DP=609 GT:AD:DP ./.:0:0 chr1 12587 . G . . . AN=746;DP=632 GT:AD:DP ./.:0:0 chr1 12588 . G . . . AN=756;DP=644 GT:AD:DP ./.:0:0 chr1 12589 . C . . . AN=758;DP=655 GT:AD:DP ./.:0:0 chr1 12590 . C . . . AN=756;DP=661 GT:AD:DP ./.:0:0 chr1 12591 . C . . . AN=758;DP=672 GT:AD:DP ./.:0:0 chr1 12592 . C . . . AN=768;DP=679 GT:AD:DP ./.:0:0 chr1 12593 . A . . . AN=760;DP=687 GT:AD:DP ./.:0:0 chr1 12594 . G . . . AN=780;DP=694 GT:AD:DP ./.:0:0 chr1 12595 . G . . . AN=776;DP=706 GT:AD:DP ./.:0:0 bcftools-1.21/test/gvcfz.vcf000066400000000000000000005377421467060157400161020ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##ALT= ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##reference=file:GRCh38_full_analysis_set_plus_decoy_hla.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HGDP01406 chr1 10001 . T . . . AN=142;DP=1225 GT:AD:DP:RGQ ./.:9:10:0 chr1 10002 . A . . . AN=210;DP=1484 GT:AD:DP:RGQ ./.:9:10:0 chr1 10003 . A . . . AN=282;DP=1841 GT:AD:DP:RGQ ./.:5:6:0 chr1 10004 . C . . . AN=372;DP=3134 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10005 . C . . . AN=418;DP=4796 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10006 . C . . . AN=452;DP=6739 GT:AD:DP:RGQ ./.:9:10:0 chr1 10007 . T . . . AN=448;DP=7774 GT:AD:DP:RGQ ./.:7:8:0 chr1 10008 . A . . . AN=484;DP=8907 GT:AD:DP:RGQ 0/0:8:8:12 chr1 10009 . A . . . AN=472;DP=9764 GT:AD:DP:RGQ ./.:7:10:0 chr1 10010 . C . . . AN=628;DP=10778 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10011 . C . . . AN=654;DP=11507 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10012 . C . . . AN=642;DP=12220 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10013 . T . . . AN=610;DP=12731 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10014 . A . . . AN=660;DP=13276 GT:AD:DP:RGQ 0/0:10:10:12 chr1 10015 . A . . . AN=638;DP=13515 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10016 . C . . . AN=842;DP=14415 GT:AD:DP:RGQ 0/0:11:11:12 chr1 10017 . C . . . AN=892;DP=14946 GT:AD:DP:RGQ 0/0:11:11:12 chr1 10018 . C . . . AN=890;DP=15476 GT:AD:DP:RGQ 0/0:13:13:12 chr1 10019 . T . . . AN=850;DP=15757 GT:AD:DP:RGQ 0/0:13:13:12 chr1 10020 . A C . . AC=0;AF=0;AN=876;BaseQRankSum=-1.026;ClippingRankSum=-1.026;DP=16219;ExcessHet=3.01;MQ=0.64;MQRankSum=-1.026;ReadPosRankSum=0 GT:AD:DP:RGQ 0/0:14,0:14:12 chr1 10021 . A . . . AN=862;DP=16482 GT:AD:DP:RGQ 0/0:12:12:12 chr1 10022 . C . . . AN=1080;DP=17445 GT:AD:DP:RGQ 0/0:16:16:15 chr1 10023 . C A . . AC=0;AF=0;AN=1108;BaseQRankSum=0;ClippingRankSum=-1.026;DP=17982;ExcessHet=3.01;MQ=0.42;MQRankSum=-1.026;ReadPosRankSum=-1.026 GT:AD:DP:RGQ 0/0:17,0:17:15 chr1 10024 . C . . . AN=1092;DP=18489 GT:AD:DP:RGQ 0/0:17:17:15 chr1 10025 . T . . . AN=1006;DP=18703 GT:AD:DP:RGQ 0/0:15:17:1 chr1 10026 . A . . . AN=1042;DP=19207 GT:AD:DP:RGQ ./.:11:13:0 chr1 10027 . A . . . AN=964;DP=19358 GT:AD:DP:RGQ ./.:12:14:0 chr1 10028 . C . . . AN=1252;DP=20434 GT:AD:DP:RGQ 0/0:17:18:12 chr1 10029 . C . . . AN=1314;DP=20989 GT:AD:DP:RGQ 0/0:19:19:21 chr1 10030 . C . . . AN=1262;DP=21509 GT:AD:DP:RGQ 0/0:19:19:21 chr1 10031 . T . . . AN=1094;DP=21589 GT:AD:DP:RGQ 0/0:16:17:9 chr1 10032 . A . . . AN=1150;DP=22097 GT:AD:DP:RGQ 0/0:16:17:5 chr1 10033 . A . . . AN=1018;DP=22181 GT:AD:DP:RGQ 0/0:13:13:21 chr1 10034 . C . . . AN=1352;DP=23420 GT:AD:DP:RGQ 0/0:19:19:21 chr1 10035 . C . . . AN=1430;DP=24000 GT:AD:DP:RGQ 0/0:19:19:21 chr1 10036 . C . . . AN=1384;DP=24433 GT:AD:DP:RGQ 0/0:18:19:11 chr1 10037 . T C . . AC=0;AF=0;AN=1196;BaseQRankSum=-1.067;ClippingRankSum=-0.572;DP=24414;ExcessHet=3.01;MQ=0.7;MQRankSum=1.59;ReadPosRankSum=-1.589 GT:AD:DP:RGQ ./.:12,3:15:0 chr1 10038 . A . . . AN=1234;DP=24915 GT:AD:DP:RGQ ./.:16:19:0 chr1 10039 . A . . . AN=1126;DP=24871 GT:AD:DP:RGQ ./.:11:13:0 chr1 10040 . C . . . AN=1458;DP=26306 GT:AD:DP:RGQ 0/0:19:19:15 chr1 10041 . C . . . AN=1546;DP=26876 GT:AD:DP:RGQ 0/0:20:20:15 chr1 10042 . C T . . AC=0;AF=0;AN=1450;BaseQRankSum=-0.572;ClippingRankSum=0.572;DP=27202;ExcessHet=3.01;MQ=0.62;MQRankSum=1.59;ReadPosRankSum=-1.589 GT:AD:DP:RGQ ./.:17,3:20:0 chr1 10043 . T . . . AN=1234;DP=27403 GT:AD:DP:RGQ 0/0:22:24:2 chr1 10044 . A . . . AN=1340;DP=28147 GT:AD:DP:RGQ 0/0:20:22:24 chr1 10045 . A . . . AN=1214;DP=28029 GT:AD:DP:RGQ 0/0:20:20:24 chr1 10046 . C . . . AN=1594;DP=30003 GT:AD:DP:RGQ 0/0:24:24:24 chr1 10047 . C . . . AN=1698;DP=30908 GT:AD:DP:RGQ 0/0:24:24:24 chr1 10048 . C . . . AN=1618;DP=31592 GT:AD:DP:RGQ 0/0:23:24:24 chr1 10049 . T C . . AC=0;AF=0;AN=1312;BaseQRankSum=-0.691;ClippingRankSum=-0.296;DP=31423;ExcessHet=3.01;MQ=0.76;MQRankSum=0.731;ReadPosRankSum=0.731 GT:AD:DP:RGQ ./.:20,2:22:0 chr1 10050 . A . . . AN=1398;DP=32308 GT:AD:DP:RGQ 0/0:22:24:20 chr1 10051 . A . . . AN=1204;DP=32137 GT:AD:DP:RGQ 0/0:18:19:20 chr1 10052 . C . . . AN=1624;DP=34288 GT:AD:DP:RGQ 0/0:23:23:27 chr1 10053 . C . . . AN=1754;DP=35154 GT:AD:DP:RGQ 0/0:24:24:27 chr1 10054 . C A . . AC=0;AF=0;AN=1634;BaseQRankSum=-1.768;ClippingRankSum=-0.354;DP=35626;ExcessHet=3.01;MQ=0.7;MQRankSum=-0.354;ReadPosRankSum=1.06 GT:AD:DP:RGQ 0/0:23,1:24:27 chr1 10055 . T C . . AC=0;AF=0;AN=1238;BaseQRankSum=-0.085;ClippingRankSum=-0.217;DP=35165;ExcessHet=3.01;MQ=0.94;MQRankSum=0.505;ReadPosRankSum=-0.934 GT:AD:DP:PGT:PID:RGQ ./.:19,3:22:.:.:0 chr1 10056 . A T . . AC=0;AF=0;AN=1422;BaseQRankSum=-1.953;ClippingRankSum=-0.085;DP=36206;ExcessHet=3.01;MQ=0.68;MQRankSum=-0.255;ReadPosRankSum=-1.274 GT:AD:DP:RGQ ./.:21,3:24:0 chr1 10057 . A G,C . . AC=0,0;AF=0,0;AN=1306;BaseQRankSum=1.23;ClippingRankSum=0.406;DP=35576;ExcessHet=3.01;MQ=0.82;MQRankSum=0.358;ReadPosRankSum=0.762 GT:AD:DP:RGQ 0/0:19,2,2:21:21 chr1 10058 . C . . . AN=1688;DP=38186 GT:AD:DP:RGQ 0/0:22:23:27 chr1 10059 . C . . . AN=1840;DP=39201 GT:AD:DP:RGQ 0/0:25:25:27 chr1 10060 . C G . . AC=0;AF=0;AN=1728;BaseQRankSum=-1.626;ClippingRankSum=-0.287;DP=39538;ExcessHet=3.01;MQ=0.8;MQRankSum=0.957;ReadPosRankSum=2.3 GT:AD:DP:RGQ 0/0:24,2:26:7 chr1 10061 . T C . . AC=0;AF=0;AN=1480;BaseQRankSum=-1.055;ClippingRankSum=0.754;DP=38726;ExcessHet=3.01;MQ=0.74;MQRankSum=1.66;ReadPosRankSum=-1.759 GT:AD:DP:RGQ ./.:20,6:26:0 chr1 10062 . A . . . AN=1666;DP=39902 GT:AD:DP:RGQ ./.:22:25:0 chr1 10063 . A . . . AN=1468;DP=38892 GT:AD:DP:RGQ ./.:19:22:0 chr1 10064 . C A . . AC=0;AF=0;AN=1780;BaseQRankSum=-1.191;ClippingRankSum=-0.764;DP=41451;ExcessHet=3.01;MQ=0.75;MQRankSum=-0.714;ReadPosRankSum=0.085 GT:AD:DP:RGQ ./.:22,2:24:0 chr1 10065 . C . . . AN=1866;DP=42364 GT:AD:DP:RGQ 0/0:29:30:48 chr1 10066 . C . . . AN=1800;DP=42517 GT:AD:DP:RGQ 0/0:29:30:44 chr1 10067 . T . . . AN=1618;DP=41473 GT:AD:DP:RGQ 0/0:24:26:11 chr1 10068 . A . . . AN=1696;DP=42685 GT:AD:DP:RGQ 0/0:29:30:60 chr1 10069 . A . . . AN=1636;DP=41463 GT:AD:DP:RGQ 0/0:28:30:48 chr1 10070 . C . . . AN=1862;DP=44361 GT:AD:DP:RGQ 0/0:30:33:24 chr1 10071 . C . . . AN=1892;DP=45033 GT:AD:DP:RGQ 0/0:34:34:66 chr1 10072 . C . . . AN=1852;DP=44940 GT:AD:DP:RGQ 0/0:31:31:66 chr1 10073 . T . . . AN=1694;DP=43326 GT:AD:DP:RGQ 0/0:30:31:66 chr1 10074 . A . . . AN=1800;DP=44368 GT:AD:DP:RGQ 0/0:31:32:66 chr1 10075 . A . . . AN=1766;DP=42682 GT:AD:DP:RGQ 0/0:28:28:66 chr1 10076 . C . . . AN=1882;DP=45295 GT:AD:DP:RGQ 0/0:31:32:66 chr1 10077 . C . . . AN=1890;DP=45723 GT:AD:DP:RGQ 0/0:34:34:66 chr1 10078 . C . . . AN=1878;DP=45370 GT:AD:DP:RGQ 0/0:32:32:66 chr1 10079 . T . . . AN=1746;DP=43529 GT:AD:DP:RGQ 0/0:29:30:65 chr1 10080 . A . . . AN=1816;DP=44625 GT:AD:DP:RGQ 0/0:31:34:27 chr1 10081 . A . . . AN=1822;DP=42816 GT:AD:DP:RGQ 0/0:28:28:75 chr1 10082 . C . . . AN=1890;DP=45409 GT:AD:DP:RGQ 0/0:32:32:75 chr1 10083 . C . . . AN=1908;DP=45761 GT:AD:DP:RGQ 0/0:35:35:75 chr1 10084 . C G . . AC=0;AF=0;AN=1896;DP=45157;ExcessHet=3.01;MQ=0.52 GT:AD:DP:PGT:PID:RGQ 0/0:30,3:33:.:.:41 chr1 10085 . T . . . AN=1740;DP=43001 GT:AD:DP:RGQ 0/0:32:33:73 chr1 10086 . A . . . AN=1842;DP=44251 GT:AD:DP:RGQ 0/0:30:32:29 chr1 10087 . A . . . AN=1818;DP=42424 GT:AD:DP:RGQ 0/0:33:33:75 chr1 10088 . C . . . AN=1878;DP=44829 GT:AD:DP:RGQ 0/0:33:34:75 chr1 10089 . C . . . AN=1908;DP=45166 GT:AD:DP:RGQ 0/0:36:36:75 chr1 10090 . C . . . AN=1886;DP=44473 GT:AD:DP:RGQ ./.:31:35:0 chr1 10091 . T . . . AN=1790;DP=42136 GT:AD:DP:RGQ ./.:30:35:0 chr1 10092 . A . . . AN=1870;DP=43367 GT:AD:DP:RGQ 0/0:33:35:45 chr1 10093 . A . . . AN=1866;DP=41414 GT:AD:DP:RGQ ./.:27:30:0 chr1 10094 . C . . . AN=1898;DP=43793 GT:AD:DP:RGQ 0/0:33:34:70 chr1 10095 . C . . . AN=1906;DP=44121 GT:AD:DP:RGQ 0/0:37:37:75 chr1 10096 . C . . . AN=1884;DP=43213 GT:AD:DP:RGQ 0/0:34:35:63 chr1 10097 . T . . . AN=1746;DP=40716 GT:AD:DP:RGQ 0/0:32:33:73 chr1 10098 . A . . . AN=1864;DP=41862 GT:AD:DP:RGQ 0/0:35:36:75 chr1 10099 . A . . . AN=1800;DP=39808 GT:AD:DP:RGQ 0/0:34:34:75 chr1 10100 . C . . . AN=1890;DP=42197 GT:AD:DP:RGQ 0/0:35:36:78 chr1 10101 . C . . . AN=1912;DP=42210 GT:AD:DP:RGQ 0/0:40:40:78 chr1 10102 . C . . . AN=1902;DP=41021 GT:AD:DP:RGQ 0/0:36:36:78 chr1 10103 . T . . . AN=1764;DP=37934 GT:AD:DP:RGQ 0/0:32:34:45 chr1 10104 . A . . . AN=1864;DP=38851 GT:AD:DP:RGQ 0/0:37:39:46 chr1 10105 . A . . . AN=1174;DP=36442 GT:AD:DP:RGQ 0/0:34:36:25 chr1 10106 . C . . . AN=1376;DP=37958 GT:AD:DP:RGQ 0/0:34:37:22 chr1 10107 . C . . . AN=1766;DP=38020 GT:AD:DP:RGQ 0/0:37:38:66 chr1 10108 . C . . . AN=824;DP=36234 GT:AD:DP:RGQ ./.:33:38:0 chr1 10109 . A . . . AN=606;DP=35112 GT:AD:DP:RGQ ./.:32:37:0 chr1 10110 . A . . . AN=1470;DP=35911 GT:AD:DP:RGQ 0/0:38:38:30 chr1 10111 . C . . . AN=1464;DP=36153 GT:AD:DP:RGQ 0/0:36:37:30 chr1 10112 . C . . . AN=1696;DP=37152 GT:AD:DP:RGQ 0/0:39:39:30 chr1 10113 . C . . . AN=1694;DP=36832 GT:AD:DP:RGQ 0/0:36:38:22 chr1 10114 . T . . . AN=1296;DP=34281 GT:AD:DP:RGQ ./.:28:32:0 chr1 10115 . A . . . AN=1624;DP=36249 GT:AD:DP:RGQ 0/0:36:37:27 chr1 10116 . A . . . AN=1706;DP=36573 GT:AD:DP:RGQ 0/0:35:37:27 chr1 10117 . C . . . AN=1642;DP=36650 GT:AD:DP:RGQ 0/0:36:37:27 chr1 10118 . C . . . AN=1770;DP=37407 GT:AD:DP:RGQ 0/0:39:39:27 chr1 10119 . C . . . AN=1744;DP=36842 GT:AD:DP:RGQ 0/0:37:40:27 chr1 10120 . T . . . AN=1352;DP=34333 GT:AD:DP:RGQ 0/0:30:33:11 chr1 10121 . A . . . AN=1666;DP=35770 GT:AD:DP:RGQ 0/0:35:36:27 chr1 10122 . A . . . AN=1760;DP=35740 GT:AD:DP:RGQ 0/0:37:37:30 chr1 10123 . C . . . AN=1652;DP=35808 GT:AD:DP:RGQ 0/0:37:38:30 chr1 10124 . C . . . AN=1770;DP=36195 GT:AD:DP:RGQ 0/0:40:40:30 chr1 10125 . C . . . AN=1758;DP=35476 GT:AD:DP:RGQ 0/0:38:40:30 chr1 10126 . T . . . AN=1368;DP=33158 GT:AD:DP:RGQ 0/0:28:30:36 chr1 10127 . A . . . AN=1652;DP=34300 GT:AD:DP:RGQ 0/0:36:37:39 chr1 10128 . A . . . AN=1652;DP=34091 GT:AD:DP:RGQ 0/0:35:35:33 chr1 10129 . C . . . AN=1536;DP=34064 GT:AD:DP:RGQ 0/0:35:37:33 chr1 10130 . C . . . AN=1740;DP=34095 GT:AD:DP:RGQ 0/0:38:39:33 chr1 10131 . CT C . . AC=0;AF=0;AN=1718;BaseQRankSum=0.898;ClippingRankSum=-0.48;DP=33151;ExcessHet=3.01;MQ=0.61;MQRankSum=1.27;ReadPosRankSum=-0.898 GT:AD:DP:RGQ 0/0:36,1:37:33 chr1 10132 . T . . . AN=1262;DP=30953 GT:AD:DP:RGQ 0/0:33:35:33 chr1 10133 . A T,C . . AC=0,0;AF=0,0;AN=1618;BaseQRankSum=0.82;ClippingRankSum=-0.224;DP=31600;ExcessHet=3.01;MQ=0.84;MQRankSum=0.358;ReadPosRankSum=2.01 GT:AD:DP:PGT:PID:RGQ 0/0:36,3,3:39:.:.:30 chr1 10134 . ACCCTAACCCTAAC A,CCCCTAACCCTAAC,GCCCTAACCCTAAC . . AC=0,0,0;AF=0,0,0;AN=1674;BaseQRankSum=0;ClippingRankSum=-0.48;DP=31150;ExcessHet=3.01;MQ=1.11;MQRankSum=1.02;ReadPosRankSum=-1.698 GT:AD:DP:PGT:PID:RGQ 0/0:35,4,4,4:39:.:.:30 chr1 10135 . CCCTAA C 103.37 . AC=4;AF=0.002077;AN=1926;BaseQRankSum=0;ClippingRankSum=0;DP=30829;ExcessHet=34.1598;FS=0;InbreedingCoeff=-0.0627;MLEAC=4;MLEAF=0.002077;MQ=0.94;MQRankSum=1.03;QD=6.46;ReadPosRankSum=1.73;SOR=0.693 GT:AD:DP:GQ:PL 0/0:35,5:40:0:0,0,897 chr1 10136 . C . . . AN=1710;DP=30738 GT:AD:DP:RGQ 0/0:38:40:27 chr1 10137 . C A . . AC=0;AF=0;AN=1658;BaseQRankSum=-0.822;ClippingRankSum=-1.369;DP=29868;ExcessHet=3.01;MQ=0.72;MQRankSum=-0.822;ReadPosRankSum=-1.187 GT:AD:DP:RGQ 0/0:35,2:37:27 chr1 10138 . TA T 256.35 . AC=2;AF=0.001037;AN=1928;BaseQRankSum=-1.123;ClippingRankSum=-0.964;DP=27643;ExcessHet=121.32;FS=1.909;InbreedingCoeff=-0.1243;MLEAC=1;MLEAF=0.0005187;MQ=1.62;MQRankSum=-0.102;QD=34.24;ReadPosRankSum=-0.964;SOR=0.346 GT:AD:DP:GQ:PGT:PID:PL 0/0:27,6:33:0:.:.:0,0,634 chr1 10139 . A G,C . . AC=0,0;AF=0,0;AN=1506;BaseQRankSum=0.351;ClippingRankSum=-0.299;DP=28276;ExcessHet=3.01;MQ=1.19;MQRankSum=1.19;ReadPosRankSum=0.179 GT:AD:DP:RGQ 0/0:34,3,3:37:19 chr1 10140 . A AC,C . . AC=0,0;AF=0,0;AN=1534;BaseQRankSum=-0.572;ClippingRankSum=0;DP=27747;ExcessHet=3.01;MQ=0.61;MQRankSum=1.07;ReadPosRankSum=1.59 GT:AD:DP:PGT:PID:RGQ 0/0:35,2,2:37:.:.:21 chr1 10141 . C . . . AN=1344;DP=27401 GT:AD:DP:RGQ ./.:33:38:0 chr1 10142 . C . . . AN=1650;DP=27116 GT:AD:DP:RGQ 0/0:36:39:24 chr1 10143 . CTAACCCCT C . . AC=0;AF=0;AN=1558;DP=26067;ExcessHet=3.01;MQ=0.41 GT:AD:DP:RGQ 0/0:35,0:35:24 chr1 10144 . T C 815.07 . AC=3;AF=0.001567;AN=1914;BaseQRankSum=-0.942;ClippingRankSum=0.322;DP=23831;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.183;MLEAC=3;MLEAF=0.001567;MQ=1.52;MQRankSum=0.898;QD=21.45;ReadPosRankSum=0.322;SOR=0.544 GT:AD:DP:GQ:PGT:PID:PL 0/0:25,7:32:0:.:.:0,0,563 chr1 10145 . AAC A 151.43 . AC=4;AF=0.002083;AN=1920;BaseQRankSum=0.72;ClippingRankSum=0;DP=24144;ExcessHet=160.275;FS=0;InbreedingCoeff=-0.1558;MLEAC=5;MLEAF=0.002604;MQ=1.63;MQRankSum=0.764;QD=3.52;ReadPosRankSum=0.085;SOR=0.458 GT:AD:DP:GQ:PL 0/0:31,2:33:15:0,15,225 chr1 10146 . AC A 26025.4 . AC=214;AF=0.112;AN=1914;BaseQRankSum=-0.532;ClippingRankSum=-0.398;DP=21832;ExcessHet=19.5226;FS=0.819;InbreedingCoeff=0.0115;MLEAC=217;MLEAF=0.113;MQ=9.12;MQRankSum=0.358;QD=16.05;ReadPosRankSum=0.736;SOR=0.841 GT:AD:DP:GQ:PGT:PID:PL 1/1:0,19:19:33:1|1:10146_AC_A:209,33,0 chr1 10147 . CCCCT C,ACCCT . . AC=0,0;AF=0,0;AN=280;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=23027;ExcessHet=3.01;MQ=0.73;MQRankSum=0.727;ReadPosRankSum=0.727 GT:AD:DP:RGQ ./.:22,9,9:31:0 chr1 10148 . C CCTAA . . AC=0;AF=0;AN=416;BaseQRankSum=-1.026;ClippingRankSum=0;DP=23009;ExcessHet=3.01;MQ=0.62;MQRankSum=1.03;ReadPosRankSum=0 GT:AD:DP:PGT:PID:RGQ ./.:23,7:30:.:.:0 chr1 10149 . CCT C . . AC=0;AF=0;AN=1304;BaseQRankSum=0.736;ClippingRankSum=1.27;DP=22319;ExcessHet=3.01;MQ=1.02;MQRankSum=0.736;ReadPosRankSum=0.736 GT:AD:DP:PGT:PID:RGQ ./.:25,5:30:.:.:0 chr1 10150 . CT C 1490.44 . AC=2;AF=0.001073;AN=1864;BaseQRankSum=-0.922;ClippingRankSum=-0.47;DP=21029;ExcessHet=2.14748e+09;FS=3.027;InbreedingCoeff=-0.2397;MLEAC=2;MLEAF=0.001073;MQ=1.54;MQRankSum=0.198;QD=30.63;ReadPosRankSum=0.118;SOR=0.326 GT:AD:DP:GQ:PGT:PID:PL 0/0:21,6:27:0:.:.:0,0,556 chr1 10151 . T A 3248.37 . AC=3;AF=0.001604;AN=1870;BaseQRankSum=-0.922;ClippingRankSum=-0.742;DP=19977;ExcessHet=2.14748e+09;FS=1.524;InbreedingCoeff=-0.2556;MLEAC=2;MLEAF=0.00107;MQ=1.59;MQRankSum=0.742;QD=29.09;ReadPosRankSum=0;SOR=0.404 GT:AD:DP:GQ:PGT:PID:PL 0/0:19,4:23:0:.:.:0,0,495 chr1 10152 . A T 39.55 . AC=2;AF=0.001078;AN=1856;DP=20329;ExcessHet=114.931;FS=0;InbreedingCoeff=-0.1535;MLEAC=2;MLEAF=0.001078;MQ=0.21;QD=19.77;SOR=0.693 GT:AD:DP:GQ:PGT:PID:PL 0/0:22,1:23:3:.:.:0,3,45 chr1 10153 . A G 230.28 . AC=1;AF=0.0005365;AN=1864;BaseQRankSum=1.03;ClippingRankSum=0;DP=20132;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.1988;MLEAC=1;MLEAF=0.0005365;MQ=0.55;MQRankSum=0.736;QD=32.93;ReadPosRankSum=1.03;SOR=0.892 GT:AD:DP:GQ:PGT:PID:PL 0/0:21,3:24:0:.:.:0,0,608 chr1 10154 . C . . . AN=1270;DP=20527 GT:AD:DP:RGQ ./.:19:24:0 chr1 10155 . C . . . AN=1498;DP=20430 GT:AD:DP:RGQ 0/0:18:20:1 chr1 10156 . CTAACCCTAACCCTAACCCTAACCT C 98.63 . AC=1;AF=0.0005359;AN=1866;BaseQRankSum=0.762;ClippingRankSum=-1.179;DP=20015;ExcessHet=77.564;FS=0;InbreedingCoeff=-0.1213;MLEAC=1;MLEAF=0.0005359;MQ=0.79;MQRankSum=1.67;QD=10.96;ReadPosRankSum=1.59;SOR=0.941 GT:AD:DP:GQ:PGT:PID:PL 0/0:19,1:20:6:.:.:0,6,90 chr1 10157 . T C 62.24 . AC=2;AF=0.001064;AN=1880;BaseQRankSum=0.747;ClippingRankSum=0.747;DP=19277;ExcessHet=2.14748e+09;FS=2.197;InbreedingCoeff=-0.1738;MLEAC=2;MLEAF=0.001064;MQ=0.78;MQRankSum=0.747;QD=6.92;ReadPosRankSum=0.747;SOR=1.402 GT:AD:DP:GQ:PGT:PID:PL 0/0:15,4:19:0:.:.:0,0,393 chr1 10158 . A . . . AN=1278;DP=19621 GT:AD:DP:RGQ 0/0:17:18:6 chr1 10159 . A G,C . . AC=0,0;AF=0,0;AN=1176;BaseQRankSum=-0.72;ClippingRankSum=0.742;DP=19356;ExcessHet=3.01;MQ=0.72;MQRankSum=0.742;ReadPosRankSum=1.38 GT:AD:DP:PGT:PID:RGQ 0/0:17,1,1:18:.:.:6 chr1 10160 . C . . . AN=1364;DP=19667 GT:AD:DP:RGQ ./.:19:20:0 chr1 10161 . C . . . AN=1516;DP=19658 GT:AD:DP:RGQ ./.:20:21:0 chr1 10162 . C . . . AN=1368;DP=19309 GT:AD:DP:RGQ ./.:19:20:0 chr1 10163 . T C 61.11 . AC=1;AF=0.0005285;AN=1892;BaseQRankSum=-0.956;ClippingRankSum=0.322;DP=18670;ExcessHet=166.599;FS=0;InbreedingCoeff=-0.1679;MLEAC=2;MLEAF=0.001057;MQ=0.51;MQRankSum=-0.684;QD=7.64;ReadPosRankSum=-1.221;SOR=1.034 GT:AD:DP:GQ:PGT:PID:PL 0/0:17,4:21:0:.:.:0,0,490 chr1 10164 . A T 37.93 . AC=2;AF=0.001076;AN=1858;DP=18924;ExcessHet=68.3389;FS=0;InbreedingCoeff=-0.1175;MLEAC=1;MLEAF=0.0005382;MQ=0.22;QD=18.96;SOR=0.693 GT:AD:DP:GQ:PGT:PID:PL 0/0:21,1:22:6:.:.:0,6,90 chr1 10165 . A C,G . . AC=0,0;AF=0,0;AN=1134;BaseQRankSum=0.736;ClippingRankSum=0;DP=18656;ExcessHet=3.01;MQ=0.81;MQRankSum=0;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID:RGQ ./.:19,5,5:24:.:.:0 chr1 10166 . C . . . AN=1372;DP=18881 GT:AD:DP:RGQ ./.:19:24:0 chr1 10167 . C . . . AN=1354;DP=18848 GT:AD:DP:RGQ 0/0:20:22:6 chr1 10168 . CTAACCCTAACCT C . . AC=0;AF=0;AN=1198;BaseQRankSum=1.22;ClippingRankSum=0.322;DP=18552;ExcessHet=3.01;MQ=0.97;MQRankSum=0.322;ReadPosRankSum=3.14 GT:AD:DP:PGT:PID:RGQ ./.:18,2:20:.:.:0 chr1 10169 . T . . . AN=776;DP=17980 GT:AD:DP:RGQ ./.:13:18:0 chr1 10170 . AACCCT A . . AC=0;AF=0;AN=1064;DP=18138;ExcessHet=3.01;MQ=0.44 GT:AD:DP:PGT:PID:RGQ ./.:19,3:22:.:.:0 chr1 10171 . A G,C . . AC=0,0;AF=0,0;AN=800;BaseQRankSum=0.572;ClippingRankSum=-1.026;DP=17854;ExcessHet=3.01;MQ=0.78;MQRankSum=0.736;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID:RGQ ./.:19,3,3:22:.:.:0 chr1 10172 . CCCTAA C . . AC=0;AF=0;AN=582;DP=18024;ExcessHet=3.01;MQ=0.31 GT:AD:DP:RGQ 0/0:18,2:20:1 chr1 10173 . C . . . AN=462;DP=18018 GT:AD:DP:RGQ ./.:19:22:0 chr1 10174 . CTAACCT C 130.07 . AC=2;AF=0.001112;AN=1798;BaseQRankSum=0.762;ClippingRankSum=-0.067;DP=17745;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2796;MLEAC=8;MLEAF=0.004449;MQ=1.28;MQRankSum=2.21;QD=4.49;ReadPosRankSum=2.21;SOR=1.136 GT:AD:DP:GQ:PGT:PID:PL 0/1:2,18:20:10:0|1:10146_AC_A:171,0,10 chr1 10175 . T . . . AN=76;DP=17217 GT:AD:DP:RGQ ./.:12:17:0 chr1 10176 . A . . . AN=154;DP=17453 GT:AD:DP:RGQ ./.:12:16:0 chr1 10177 . A C 105.77 . AC=3;AF=0.002538;AN=1182;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=17331;ExcessHet=138.359;FS=0;InbreedingCoeff=-0.2972;MLEAC=39;MLEAF=0.033;MQ=0.71;MQRankSum=0.727;QD=26.44;ReadPosRankSum=-0.727;SOR=1.447 GT:AD:DP:GQ:PGT:PID:PL 0/0:10,8:18:0:.:.:0,0,21 chr1 10178 . C . . . AN=2;DP=17814 GT:AD:DP:RGQ ./.:9:17:0 chr1 10179 . C . . . AN=48;DP=17939 GT:AD:DP:RGQ ./.:12:15:0 chr1 10180 . T C 2135.86 . AC=1;AF=0.001057;AN=946;BaseQRankSum=0.779;ClippingRankSum=0.779;DP=17651;ExcessHet=157.048;FS=4.481;InbreedingCoeff=-0.295;MLEAC=2;MLEAF=0.002114;MQ=0.82;MQRankSum=1.07;QD=30.83;ReadPosRankSum=1.59;SOR=0.148 GT:AD:DP:GQ:PGT:PID:PL 0/0:9,5:14:0:.:.:0,0,49 chr1 10181 . A . . . AN=56;DP=17926 GT:AD:DP:RGQ ./.:14:18:0 chr1 10182 . A . . . AN=168;DP=18128 GT:AD:DP:RGQ ./.:15:18:0 chr1 10183 . C . . . AN=204;DP=18717 GT:AD:DP:RGQ ./.:13:17:0 chr1 10184 . C . . . AN=292;DP=19115 GT:AD:DP:RGQ ./.:16:19:0 chr1 10185 . C . . . AN=304;DP=19250 GT:AD:DP:RGQ ./.:15:17:0 chr1 10186 . T . . . AN=190;DP=18962 GT:AD:DP:RGQ ./.:10:14:0 chr1 10187 . A . . . AN=252;DP=19379 GT:AD:DP:RGQ ./.:13:17:0 chr1 10188 . A . . . AN=238;DP=19503 GT:AD:DP:RGQ ./.:16:19:0 chr1 10189 . C . . . AN=326;DP=20077 GT:AD:DP:RGQ ./.:13:16:0 chr1 10190 . C . . . AN=368;DP=20381 GT:AD:DP:RGQ ./.:16:19:0 chr1 10191 . C . . . AN=332;DP=20429 GT:AD:DP:RGQ ./.:17:19:0 chr1 10192 . T . . . AN=240;DP=20079 GT:AD:DP:RGQ ./.:17:19:0 chr1 10193 . A . . . AN=286;DP=20350 GT:AD:DP:RGQ ./.:17:19:0 chr1 10194 . A . . . AN=274;DP=20335 GT:AD:DP:RGQ ./.:15:19:0 chr1 10195 . C A . . AC=0;AF=0;AN=306;DP=20890;ExcessHet=3.01;MQ=0.46 GT:AD:DP:PGT:PID:RGQ ./.:17,2:19:.:.:0 chr1 10196 . C . . . AN=320;DP=21033 GT:AD:DP:RGQ ./.:17:19:0 chr1 10197 . C . . . AN=320;DP=20888 GT:AD:DP:RGQ ./.:15:19:0 chr1 10198 . T . . . AN=258;DP=20461 GT:AD:DP:RGQ ./.:14:19:0 chr1 10199 . A . . . AN=320;DP=20674 GT:AD:DP:RGQ ./.:18:21:0 chr1 10200 . AC A . . AC=0;AF=0;AN=302;BaseQRankSum=-0.358;ClippingRankSum=-1.231;DP=20547;ExcessHet=3.01;MQ=0.79;MQRankSum=1.23;ReadPosRankSum=-0.358 GT:AD:DP:RGQ ./.:17,2:19:0 chr1 10201 . C . . . AN=326;DP=21024 GT:AD:DP:RGQ ./.:18:21:0 chr1 10202 . C . . . AN=330;DP=21163 GT:AD:DP:RGQ ./.:15:19:0 chr1 10203 . C . . . AN=324;DP=21047 GT:AD:DP:RGQ ./.:14:19:0 chr1 10204 . T A,C . . AC=0,0;AF=0,0;AN=294;BaseQRankSum=0;ClippingRankSum=-1.067;DP=20554;ExcessHet=3.01;MQ=0.75;MQRankSum=0.572;ReadPosRankSum=1.07 GT:AD:DP:PGT:PID:RGQ ./.:15,4,4:19:.:.:0 chr1 10205 . AACCCTAACCCTAACCCTAACCCTAACCCCTAACCCT A . . AC=0;AF=0;AN=320;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=20661;ExcessHet=3.01;MQ=0.69;MQRankSum=0.727;ReadPosRankSum=0.727 GT:AD:DP:RGQ ./.:16,5:21:0 chr1 10206 . A . . . AN=314;DP=20588 GT:AD:DP:RGQ ./.:12:17:0 chr1 10207 . C . . . AN=332;DP=20970 GT:AD:DP:RGQ ./.:16:19:0 chr1 10208 . C . . . AN=342;DP=20982 GT:AD:DP:RGQ ./.:16:19:0 chr1 10209 . C . . . AN=340;DP=20829 GT:AD:DP:RGQ ./.:17:20:0 chr1 10210 . T G,C . . AC=0,0;AF=0,0;AN=292;BaseQRankSum=-0.572;ClippingRankSum=0.572;DP=20340;ExcessHet=3.01;MQ=0.82;MQRankSum=0;ReadPosRankSum=0 GT:AD:DP:PGT:PID:RGQ ./.:17,3,3:20:.:.:0 chr1 10211 . A . . . AN=324;DP=20524 GT:AD:DP:RGQ 0/0:18:20:6 chr1 10212 . A . . . AN=290;DP=20333 GT:AD:DP:RGQ ./.:16:20:0 chr1 10213 . C . . . AN=326;DP=20716 GT:AD:DP:RGQ ./.:16:20:0 chr1 10214 . C . . . AN=366;DP=20793 GT:AD:DP:RGQ ./.:17:20:0 chr1 10215 . C . . . AN=338;DP=20574 GT:AD:DP:RGQ ./.:17:20:0 chr1 10216 . T G 31.95 . AC=1;AF=0.000618;AN=1618;BaseQRankSum=-0.572;ClippingRankSum=1.59;DP=19936;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2565;MLEAC=6;MLEAF=0.003708;MQ=0.62;MQRankSum=0.572;QD=3.99;ReadPosRankSum=0;SOR=0.307 GT:AD:DP:GQ:PGT:PID:PL 0/0:16,4:20:0:.:.:0,0,365 chr1 10217 . AACCCTAACCCTAACCCCTAACCCT A . . AC=0;AF=0;AN=276;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=20135;ExcessHet=3.01;MQ=0.53;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:RGQ ./.:17,2:19:0 chr1 10218 . A . . . AN=288;DP=19871 GT:AD:DP:RGQ ./.:16:19:0 chr1 10219 . C . . . AN=358;DP=20169 GT:AD:DP:RGQ ./.:15:17:0 chr1 10220 . C . . . AN=362;DP=20215 GT:AD:DP:RGQ 0/0:16:17:9 chr1 10221 . C . . . AN=354;DP=20047 GT:AD:DP:RGQ ./.:14:17:0 chr1 10222 . T . . . AN=186;DP=19466 GT:AD:DP:RGQ ./.:13:17:0 chr1 10223 . A . . . AN=208;DP=19690 GT:AD:DP:RGQ ./.:12:17:0 chr1 10224 . A . . . AN=262;DP=19466 GT:AD:DP:RGQ 0/0:15:17:12 chr1 10225 . C . . . AN=334;DP=19844 GT:AD:DP:RGQ ./.:14:17:0 chr1 10226 . C . . . AN=378;DP=19926 GT:AD:DP:RGQ ./.:14:17:0 chr1 10227 . C . . . AN=350;DP=19824 GT:AD:DP:RGQ ./.:15:17:0 chr1 10228 . T . . . AN=212;DP=19193 GT:AD:DP:RGQ ./.:10:17:0 chr1 10229 . A . . . AN=190;DP=19311 GT:AD:DP:RGQ ./.:12:17:0 chr1 10230 . A . . . AN=16;DP=19225 GT:AD:DP:RGQ ./.:9:18:0 chr1 10231 . CCCCTAACCCTAACCCTAAACCCTAAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCAACCCCAACCCCAACCCCAACCCCAACCCCAACCCTAACCCCTAACCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAA C . . AC=0;AF=0;AN=4;DP=19160;ExcessHet=3.01;MQ=0.69 GT:AD:DP:RGQ ./.:14,3:17:0 chr1 10232 . C . . . AN=14;DP=19701 GT:AD:DP:RGQ ./.:11:17:0 chr1 10233 . C . . . AN=300;DP=19722 GT:AD:DP:RGQ ./.:10:16:0 chr1 10234 . CT C . . AC=0;AF=0;AN=118;DP=19134;ExcessHet=3.01;MQ=1 GT:AD:DP:PGT:PID:RGQ ./.:10,5:15:.:.:0 chr1 10235 . T A . . AC=0;AF=0;AN=16;DP=18692;ExcessHet=3.01;MQ=0.81 GT:AD:DP:RGQ ./.:9,6:15:0 chr1 10236 . AACCCT A 42.02 . AC=2;AF=0.001176;AN=1700;DP=19117;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.3123;MLEAC=30;MLEAF=0.018;MQ=0.83;QD=10.5;SOR=1.609 GT:AD:DP:GQ:PL 0/0:12,4:16:0:0,0,196 chr1 10237 . ACCCT A . . AC=0;AF=0;AN=66;DP=19053;ExcessHet=3.01;MQ=0.83 GT:AD:DP:PGT:PID:RGQ ./.:8,7:15:.:.:0 chr1 10238 . CCCTAA C . . AC=0;AF=0;AN=52;DP=19514;ExcessHet=3.01;MQ=0.41 GT:AD:DP:PGT:PID:RGQ ./.:10,5:15:.:.:0 chr1 10239 . C . . . AN=110;DP=19773 GT:AD:DP:RGQ ./.:10:16:0 chr1 10240 . C . . . AN=78;DP=19632 GT:AD:DP:RGQ ./.:9:15:0 chr1 10241 . T . . . AN=10;DP=18948 GT:AD:DP:RGQ ./.:7:15:0 chr1 10242 . A . . . AN=102;DP=19331 GT:AD:DP:RGQ ./.:10:16:0 chr1 10243 . A AC . . AC=0;AF=0;AN=370;DP=19286;ExcessHet=3.01;MQ=0.49 GT:AD:DP:PGT:PID:RGQ ./.:10,4:14:.:.:0 chr1 10244 . C . . . AN=242;DP=19645 GT:AD:DP:RGQ ./.:9:14:0 chr1 10245 . CCTAAACCCTA C,CAAACCCTA . . AC=0,0;AF=0,0;AN=414;DP=19870;ExcessHet=3.01;MQ=0.75 GT:AD:DP:RGQ ./.:10,5,5:15:0 chr1 10246 . C . . . AN=392;DP=19797 GT:AD:DP:RGQ ./.:9:14:0 chr1 10247 . TAAACCCTA T 5861 . AC=6;AF=0.007299;AN=822;DP=19019;ExcessHet=89.9389;FS=0;InbreedingCoeff=-0.2627;MLEAC=4;MLEAF=0.004866;MQ=1.81;QD=29.67;SOR=0.735 GT:AD:DP:GQ:PGT:PID:PL 1/1:0,2:2:6:.:.:90,6,0 chr1 10248 . A T 1541.69 . AC=2;AF=0.001427;AN=1402;DP=19322;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.299;MLEAC=1;MLEAF=0.0007133;MQ=0.82;QD=34.04;SOR=0.105 GT:AD:DP:GQ:PL ./.:4,11:15:.:. chr1 10249 . A . . . AN=106;DP=19492 GT:AD:DP:RGQ ./.:4:16:0 chr1 10250 . A C 48.14 . AC=5;AF=0.003571;AN=1400;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=19357;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.285;MLEAC=41;MLEAF=0.029;MQ=1.29;MQRankSum=0.804;QD=24.07;ReadPosRankSum=0.804;SOR=1.179 GT:AD:DP:GQ:PGT:PID:PL ./.:6,10:16:.:.:.:. chr1 10251 . C . . . AN=300;DP=19691 GT:AD:DP:RGQ ./.:6:15:0 chr1 10252 . C . . . AN=378;DP=20082 GT:AD:DP:RGQ ./.:6:15:0 chr1 10253 . C . . . AN=300;DP=19812 GT:AD:DP:RGQ ./.:8:15:0 chr1 10254 . T . . . AN=10;DP=19285 GT:AD:DP:RGQ ./.:5:14:0 chr1 10255 . A . . . AN=18;DP=19723 GT:AD:DP:RGQ ./.:6:15:0 chr1 10256 . A AGATCGG . . AC=0;AF=0;AN=90;DP=19892;ExcessHet=3.01;MQ=0.73 GT:AD:DP:RGQ ./.:9,8:17:0 chr1 10257 . A C 179.42 . AC=5;AF=0.003071;AN=1628;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=19756;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2959;MLEAC=47;MLEAF=0.029;MQ=1.24;MQRankSum=0.804;QD=32.42;ReadPosRankSum=0.804;SOR=0.105 GT:AD:DP:GQ:PGT:PID:PL 0/0:11,5:16:0:.:.:0,0,117 chr1 10258 . C . . . AN=580;DP=20650 GT:AD:DP:RGQ ./.:12:17:0 chr1 10259 . C . . . AN=632;DP=20735 GT:AD:DP:RGQ ./.:13:16:0 chr1 10260 . C . . . AN=634;DP=20380 GT:AD:DP:RGQ ./.:11:15:0 chr1 10261 . T . . . AN=164;DP=19444 GT:AD:DP:RGQ ./.:10:15:0 chr1 10262 . AACCCT A . . AC=0;AF=0;AN=290;DP=19963;ExcessHet=3.01;MQ=0.45 GT:AD:DP:RGQ ./.:12,4:16:0 chr1 10263 . A . . . AN=378;DP=19696 GT:AD:DP:RGQ ./.:12:16:0 chr1 10264 . C . . . AN=612;DP=20270 GT:AD:DP:RGQ ./.:13:16:0 chr1 10265 . C . . . AN=844;DP=20341 GT:AD:DP:RGQ ./.:12:17:0 chr1 10266 . C . . . AN=782;DP=20007 GT:AD:DP:RGQ ./.:13:17:0 chr1 10267 . T . . . AN=186;DP=18974 GT:AD:DP:RGQ ./.:13:16:0 chr1 10268 . A . . . AN=446;DP=19382 GT:AD:DP:RGQ ./.:13:17:0 chr1 10269 . A . . . AN=526;DP=19005 GT:AD:DP:RGQ ./.:10:17:0 chr1 10270 . C . . . AN=878;DP=19614 GT:AD:DP:RGQ ./.:13:17:0 chr1 10271 . C . . . AN=1054;DP=19601 GT:AD:DP:RGQ ./.:13:17:0 chr1 10272 . C . . . AN=1050;DP=19303 GT:AD:DP:RGQ ./.:14:16:0 chr1 10273 . T C,G . . AC=0,0;AF=0,0;AN=304;BaseQRankSum=-0.727;ClippingRankSum=-0.727;DP=18171;ExcessHet=3.01;MQ=1.25;MQRankSum=0.727;ReadPosRankSum=0.727 GT:AD:DP:PGT:PID:RGQ ./.:12,3,3:15:.:.:0 chr1 10274 . A . . . AN=766;DP=18557 GT:AD:DP:RGQ ./.:12:17:0 chr1 10275 . A . . . AN=750;DP=18160 GT:AD:DP:RGQ ./.:12:15:0 chr1 10276 . C . . . AN=1094;DP=18631 GT:AD:DP:RGQ ./.:15:17:0 chr1 10277 . C . . . AN=1284;DP=18578 GT:AD:DP:RGQ ./.:14:17:0 chr1 10278 . C . . . AN=1252;DP=18211 GT:AD:DP:RGQ ./.:14:18:0 chr1 10279 . T . . . AN=398;DP=16981 GT:AD:DP:RGQ ./.:11:17:0 chr1 10280 . A . . . AN=924;DP=17424 GT:AD:DP:RGQ ./.:15:18:0 chr1 10281 . A . . . AN=848;DP=17071 GT:AD:DP:RGQ ./.:12:16:0 chr1 10282 . CCCTAACCCCAACCCCAACCCCAACCCCAACCCCAACCCCAACCCTAACCCCTAACCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTCGCGGTACCCTCAG C . . AC=0;AF=0;AN=1122;DP=17681;ExcessHet=3.01;MQ=0.75 GT:AD:DP:RGQ ./.:17,2:19:0 chr1 10283 . C . . . AN=1360;DP=17755 GT:AD:DP:RGQ ./.:15:19:0 chr1 10284 . C . . . AN=1256;DP=17502 GT:AD:DP:RGQ ./.:13:18:0 chr1 10285 . T C,G . . AC=0,0;AF=0,0;AN=310;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=16280;ExcessHet=3.01;MQ=1.19;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:PGT:PID:RGQ ./.:11,4,4:15:.:.:0 chr1 10286 . A . . . AN=706;DP=16747 GT:AD:DP:RGQ ./.:12:15:0 chr1 10287 . A . . . AN=728;DP=16239 GT:AD:DP:RGQ ./.:12:16:0 chr1 10288 . C . . . AN=980;DP=17164 GT:AD:DP:RGQ 0/0:16:17:12 chr1 10289 . C . . . AN=1092;DP=17419 GT:AD:DP:RGQ ./.:15:17:0 chr1 10290 . C . . . AN=1068;DP=17300 GT:AD:DP:RGQ ./.:13:15:0 chr1 10291 . C T 82.46 . AC=3;AF=0.001765;AN=1700;BaseQRankSum=0.736;ClippingRankSum=0.731;DP=16236;ExcessHet=2.14748e+09;FS=1.778;InbreedingCoeff=-0.2876;MLEAC=20;MLEAF=0.012;MQ=1.79;MQRankSum=0.731;QD=6.87;ReadPosRankSum=-0.731;SOR=0.283 GT:AD:DP:GQ:PGT:PID:PL 0/0:11,4:15:0:.:.:0,0,257 chr1 10292 . A . . . AN=578;DP=16364 GT:AD:DP:RGQ ./.:13:16:0 chr1 10293 . A . . . AN=698;DP=15972 GT:AD:DP:RGQ ./.:10:14:0 chr1 10294 . C . . . AN=912;DP=17094 GT:AD:DP:RGQ ./.:13:16:0 chr1 10295 . C . . . AN=1044;DP=17388 GT:AD:DP:RGQ ./.:13:16:0 chr1 10296 . C . . . AN=968;DP=17365 GT:AD:DP:RGQ ./.:14:19:0 chr1 10297 . C T 680.86 . AC=3;AF=0.00167;AN=1796;BaseQRankSum=-0.729;ClippingRankSum=0.729;DP=16568;ExcessHet=171.365;FS=8.022;InbreedingCoeff=-0.2456;MLEAC=4;MLEAF=0.002227;MQ=1.92;MQRankSum=0.72;QD=34.04;ReadPosRankSum=0.361;SOR=0.086 GT:AD:DP:GQ:PGT:PID:PL 0/0:12,5:17:0:.:.:0,0,201 chr1 10298 . A . . . AN=556;DP=16437 GT:AD:DP:RGQ ./.:10:15:0 chr1 10299 . A . . . AN=640;DP=16131 GT:AD:DP:RGQ ./.:9:15:0 chr1 10300 . C . . . AN=880;DP=17272 GT:AD:DP:RGQ ./.:12:17:0 chr1 10301 . C . . . AN=1012;DP=17726 GT:AD:DP:RGQ ./.:15:19:0 chr1 10302 . C . . . AN=942;DP=17775 GT:AD:DP:RGQ ./.:14:19:0 chr1 10303 . C . . . AN=658;DP=17118 GT:AD:DP:RGQ ./.:13:17:0 chr1 10304 . A . . . AN=576;DP=16845 GT:AD:DP:RGQ ./.:13:20:0 chr1 10305 . A . . . AN=682;DP=16709 GT:AD:DP:RGQ ./.:13:19:0 chr1 10306 . C . . . AN=862;DP=17858 GT:AD:DP:RGQ ./.:11:19:0 chr1 10307 . C . . . AN=998;DP=18410 GT:AD:DP:RGQ ./.:17:22:0 chr1 10308 . C . . . AN=954;DP=18429 GT:AD:DP:RGQ ./.:17:22:0 chr1 10309 . C . . . AN=702;DP=17851 GT:AD:DP:RGQ ./.:14:21:0 chr1 10310 . A . . . AN=548;DP=17533 GT:AD:DP:RGQ ./.:14:20:0 chr1 10311 . A . . . AN=624;DP=17562 GT:AD:DP:RGQ ./.:14:20:0 chr1 10312 . C . . . AN=750;DP=18917 GT:AD:DP:RGQ ./.:16:20:0 chr1 10313 . C . . . AN=862;DP=19821 GT:AD:DP:RGQ ./.:18:21:0 chr1 10314 . C . . . AN=808;DP=20210 GT:AD:DP:RGQ ./.:16:22:0 chr1 10315 . C T,A . . AC=0,0;AF=0,0;AN=522;BaseQRankSum=0.358;ClippingRankSum=-0.322;DP=19802;ExcessHet=3.01;MQ=1.43;MQRankSum=0.967;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID:RGQ ./.:14,7,7:21:.:.:0 chr1 10316 . A . . . AN=346;DP=20040 GT:AD:DP:RGQ ./.:15:25:0 chr1 10317 . A . . . AN=386;DP=20533 GT:AD:DP:RGQ ./.:14:26:0 chr1 10318 . CCCCAA C 456.85 . AC=1;AF=0.000533;AN=1876;BaseQRankSum=0.354;ClippingRankSum=-1.626;DP=21573;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2247;MLEAC=1;MLEAF=0.000533;MQ=0.86;MQRankSum=0.212;QD=32.63;ReadPosRankSum=0.778;SOR=0.188 GT:AD:DP:GQ:PGT:PID:PL 0/0:16,7:23:0:.:.:0,0,319 chr1 10319 . C . . . AN=592;DP=22588 GT:AD:DP:RGQ ./.:19:24:0 chr1 10320 . C CT 75.13 . AC=1;AF=0.0005302;AN=1886;BaseQRankSum=0.212;ClippingRankSum=-1.626;DP=22754;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2209;MLEAC=3;MLEAF=0.001591;MQ=0.93;MQRankSum=-0.354;QD=5.37;ReadPosRankSum=-0.354;SOR=0.188 GT:AD:DP:GQ:PGT:PID:PL 0/0:21,5:26:0:.:.:0,0,518 chr1 10321 . CAACCCT AAACCCT,C 3609.36 . AC=1,1;AF=0.000578,0.000578;AN=1730;BaseQRankSum=0.919;ClippingRankSum=-0.583;DP=21763;ExcessHet=3.0404;FS=0;InbreedingCoeff=0.1139;MLEAC=1,1;MLEAF=0.000578,0.000578;MQ=2.31;MQRankSum=0.727;QD=37.76;ReadPosRankSum=0.727;SOR=0.576 GT:AD:DP:GQ:PGT:PID:PL 0/0:16,4,4:20:0:.:.:0,0,411,0,411,411 chr1 10322 . A . . . AN=176;DP=22080 GT:AD:DP:RGQ ./.:16:22:0 chr1 10323 . A . . . AN=262;DP=22355 GT:AD:DP:RGQ ./.:14:24:0 chr1 10324 . C . . . AN=396;DP=22791 GT:AD:DP:RGQ ./.:19:23:0 chr1 10325 . C . . . AN=536;DP=23339 GT:AD:DP:RGQ ./.:20:25:0 chr1 10326 . C . . . AN=466;DP=23203 GT:AD:DP:RGQ ./.:20:24:0 chr1 10327 . T C 2588.75 . AC=17;AF=0.021;AN=824;BaseQRankSum=0.736;ClippingRankSum=-0.421;DP=21952;ExcessHet=69.3203;FS=1.725;InbreedingCoeff=-0.2455;MLEAC=17;MLEAF=0.021;MQ=2.25;MQRankSum=0.421;QD=27.64;ReadPosRankSum=-0.736;SOR=0.155 GT:AD:DP:GQ:PGT:PID:PL 0/0:15,8:23:0:.:.:0,0,200 chr1 10328 . A . . . AN=60;DP=22075 GT:AD:DP:RGQ ./.:14:23:0 chr1 10329 . AC A 104.73 . AC=1;AF=0.000821;AN=1218;BaseQRankSum=-0.922;ClippingRankSum=0.198;DP=22458;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2983;MLEAC=31;MLEAF=0.025;MQ=0.64;MQRankSum=-0.922;QD=14.96;ReadPosRankSum=-0.922;SOR=0.527 GT:AD:DP:GQ:PL ./.:11,13:24:.:. chr1 10330 . C A 249.83 . AC=4;AF=0.002663;AN=1502;BaseQRankSum=0.358;ClippingRankSum=1.23;DP=22430;ExcessHet=2.14748e+09;FS=13.239;InbreedingCoeff=-0.3036;MLEAC=52;MLEAF=0.035;MQ=1.19;MQRankSum=1.23;QD=10.86;ReadPosRankSum=0.358;SOR=0.018 GT:AD:DP:GQ:PGT:PID:PL 0/0:18,8:26:0:.:.:0,0,386 chr1 10331 . C . . . AN=102;DP=23575 GT:AD:DP:RGQ ./.:18:24:0 chr1 10332 . C . . . AN=456;DP=23775 GT:AD:DP:RGQ ./.:19:24:0 chr1 10333 . C T 1275.3 . AC=1;AF=0.0005747;AN=1740;BaseQRankSum=0.324;ClippingRankSum=1.62;DP=23222;ExcessHet=2.14748e+09;FS=2.754;InbreedingCoeff=-0.3125;MLEAC=1;MLEAF=0.0005747;MQ=1.34;MQRankSum=1.16;QD=29.43;ReadPosRankSum=1.44;SOR=2.303 GT:AD:DP:GQ:PGT:PID:PL 0/0:15,12:27:0:.:.:0,0,136 chr1 10334 . T A . . AC=0;AF=0;AN=24;DP=22701;ExcessHet=3.01;MQ=0.65 GT:AD:DP:PGT:PID:RGQ ./.:9,15:24:.:.:0 chr1 10335 . A . . . AN=64;DP=23149 GT:AD:DP:RGQ ./.:13:22:0 chr1 10336 . A . . . AN=34;DP=23067 GT:AD:DP:RGQ ./.:12:24:0 chr1 10337 . CCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTCGCGGTACCCTCAG CCCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTCGCGGTACCCTCAG,C . . AC=0,0;AF=0,0;AN=360;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=24001;ExcessHet=3.01;MQ=1.45;MQRankSum=0.804 GT:AD:DP:PGT:PID:RGQ ./.:23,3,3:26:.:.:0 chr1 10338 . C . . . AN=428;DP=24182 GT:AD:DP:RGQ ./.:18:26:0 chr1 10339 . C . . . AN=304;DP=24010 GT:AD:DP:RGQ ./.:21:26:0 chr1 10340 . T C . . AC=0;AF=0;AN=58;DP=23357;ExcessHet=3.01;MQ=0.54 GT:AD:DP:PGT:PID:RGQ ./.:16,9:25:.:.:0 chr1 10341 . A . . . AN=174;DP=23764 GT:AD:DP:RGQ ./.:15:25:0 chr1 10342 . A . . . AN=86;DP=23630 GT:AD:DP:RGQ ./.:14:27:0 chr1 10343 . C . . . AN=348;DP=24415 GT:AD:DP:RGQ 0/0:24:26:12 chr1 10344 . C . . . AN=368;DP=24672 GT:AD:DP:RGQ ./.:21:26:0 chr1 10345 . C . . . AN=306;DP=24463 GT:AD:DP:RGQ ./.:21:26:0 chr1 10346 . T . . . AN=96;DP=23942 GT:AD:DP:RGQ ./.:14:23:0 chr1 10347 . AACCCT A 932.95 . AC=3;AF=0.001987;AN=1510;BaseQRankSum=0.309;ClippingRankSum=-0.639;DP=24240;ExcessHet=2.14748e+09;FS=11.678;InbreedingCoeff=-0.2736;MLEAC=17;MLEAF=0.011;MQ=1.55;MQRankSum=-0.062;QD=25.21;ReadPosRankSum=-0.493;SOR=3.545 GT:AD:DP:GQ:PGT:PID:PL 0/0:16,7:23:0:.:.:0,0,185 chr1 10348 . A . . . AN=40;DP=24058 GT:AD:DP:RGQ ./.:15:24:0 chr1 10349 . C . . . AN=176;DP=24866 GT:AD:DP:RGQ ./.:17:25:0 chr1 10350 . C . . . AN=208;DP=25160 GT:AD:DP:RGQ 0/0:22:24:15 chr1 10351 . C . . . AN=78;DP=24759 GT:AD:DP:RGQ ./.:18:25:0 chr1 10352 . T A 207.96 . AC=8;AF=0.023;AN=346;BaseQRankSum=0.678;ClippingRankSum=-0.597;DP=24118;ExcessHet=8.5748;FS=1.922;InbreedingCoeff=-0.2449;MLEAC=43;MLEAF=0.124;MQ=1.54;MQRankSum=0.278;QD=9.04;ReadPosRankSum=0;SOR=0.209 GT:AD:DP:GQ:PL ./.:12,12:24:.:. chr1 10353 . A AAC . . AC=0;AF=0;AN=6;DP=24666;ExcessHet=3.01;MQ=0.87 GT:AD:DP:RGQ ./.:9,14:23:0 chr1 10354 . C A 489.89 . AC=9;AF=0.006148;AN=1464;BaseQRankSum=-0.48;ClippingRankSum=0.48;DP=25045;ExcessHet=2.14748e+09;FS=8.181;InbreedingCoeff=-0.3158;MLEAC=98;MLEAF=0.067;MQ=2.6;MQRankSum=0.595;QD=4.62;ReadPosRankSum=0.48;SOR=0.179 GT:AD:DP:GQ:PL ./.:11,13:24:.:. chr1 10355 . C . . . AN=252;DP=25997 GT:AD:DP:RGQ ./.:18:22:0 chr1 10356 . C . . . AN=268;DP=26017 GT:AD:DP:RGQ ./.:20:23:0 chr1 10357 . T C,G . . AC=0,0;AF=0,0;AN=52;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=25371;ExcessHet=3.01;MQ=1.17;MQRankSum=0.804;ReadPosRankSum=1.47 GT:AD:DP:RGQ ./.:20,4,4:24:0 chr1 10358 . A G,T . . AC=0,0;AF=0,0;AN=172;BaseQRankSum=0.747;ClippingRankSum=0.747;DP=25875;ExcessHet=3.01;MQ=1.27;MQRankSum=-0.747;ReadPosRankSum=0.747 GT:AD:DP:RGQ ./.:16,8,8:24:0 chr1 10359 . A C . . AC=0;AF=0;AN=184;BaseQRankSum=1.03;ClippingRankSum=-1.026;DP=25950;ExcessHet=3.01;MQ=0.57;MQRankSum=1.03;ReadPosRankSum=-1.026 GT:AD:DP:RGQ ./.:15,9:24:0 chr1 10360 . C G . . AC=0;AF=0;AN=288;DP=27357;ExcessHet=3.01;MQ=0.48 GT:AD:DP:RGQ ./.:20,4:24:0 chr1 10361 . C G . . AC=0;AF=0;AN=382;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=27964;ExcessHet=3.01;MQ=0.66;MQRankSum=0.804;ReadPosRankSum=0.804 GT:AD:DP:RGQ 0/0:23,1:24:27 chr1 10362 . C . . . AN=380;DP=28044 GT:AD:DP:RGQ ./.:20:24:0 chr1 10363 . T C . . AC=0;AF=0;AN=222;BaseQRankSum=0.736;ClippingRankSum=-0.537;DP=27560;ExcessHet=3.01;MQ=0.88;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:RGQ ./.:18,6:24:0 chr1 10364 . A C,T . . AC=0,0;AF=0,0;AN=320;BaseQRankSum=-0.825;ClippingRankSum=-0.354;DP=28131;ExcessHet=3.01;MQ=1.08;MQRankSum=-0.589;ReadPosRankSum=-1.061 GT:AD:DP:RGQ ./.:16,10,10:26:0 chr1 10365 . A . . . AN=282;DP=28154 GT:AD:DP:RGQ ./.:19:28:0 chr1 10366 . C . . . AN=376;DP=29483 GT:AD:DP:RGQ ./.:22:26:0 chr1 10367 . C T . . AC=0;AF=0;AN=416;BaseQRankSum=-1.733;ClippingRankSum=0.179;DP=29873;ExcessHet=3.01;MQ=1.01;MQRankSum=1.26;ReadPosRankSum=1.61 GT:AD:DP:RGQ 0/0:25,1:26:30 chr1 10368 . C T . . AC=0;AF=0;AN=440;BaseQRankSum=-0.358;ClippingRankSum=-1.231;DP=29898;ExcessHet=3.01;MQ=0.48;MQRankSum=0.358;ReadPosRankSum=-1.231 GT:AD:DP:RGQ 0/0:26,0:26:30 chr1 10369 . T G . . AC=0;AF=0;AN=274;BaseQRankSum=-0.747;ClippingRankSum=0.747;DP=29200;ExcessHet=3.01;MQ=0.49;MQRankSum=0.747;ReadPosRankSum=0.747 GT:AD:DP:RGQ 0/0:24,2:26:9 chr1 10370 . A . . . AN=326;DP=29764 GT:AD:DP:RGQ ./.:20:27:0 chr1 10371 . A C . . AC=0;AF=0;AN=332;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=29416;ExcessHet=3.01;MQ=1.23;MQRankSum=-0.736;ReadPosRankSum=-0.736 GT:AD:DP:RGQ ./.:22,5:27:0 chr1 10372 . C . . . AN=394;DP=30851 GT:AD:DP:RGQ 0/0:27:27:33 chr1 10373 . C . . . AN=414;DP=31229 GT:AD:DP:RGQ ./.:25:27:0 chr1 10374 . C . . . AN=430;DP=31052 GT:AD:DP:RGQ 0/0:26:27:33 chr1 10375 . T C . . AC=0;AF=0;AN=294;BaseQRankSum=0.48;ClippingRankSum=-1.067;DP=30201;ExcessHet=3.01;MQ=1.14;MQRankSum=0.898;ReadPosRankSum=-0.572 GT:AD:DP:RGQ 0/0:24,3:27:5 chr1 10376 . A . . . AN=310;DP=30711 GT:AD:DP:RGQ ./.:22:27:0 chr1 10377 . A . . . AN=292;DP=30356 GT:AD:DP:RGQ ./.:19:27:0 chr1 10378 . C . . . AN=412;DP=31668 GT:AD:DP:RGQ ./.:24:27:0 chr1 10379 . C A . . AC=0;AF=0;AN=466;BaseQRankSum=0.72;ClippingRankSum=0;DP=31981;ExcessHet=3.01;MQ=0.44;MQRankSum=-0.72;ReadPosRankSum=1.38 GT:AD:DP:RGQ 0/0:27,0:27:33 chr1 10380 . C . . . AN=492;DP=31713 GT:AD:DP:RGQ 0/0:25:27:18 chr1 10381 . T C . . AC=0;AF=0;AN=322;DP=30584;ExcessHet=3.01;MQ=0.67 GT:AD:DP:RGQ ./.:24,5:29:0 chr1 10382 . A . . . AN=308;DP=31029 GT:AD:DP:RGQ ./.:24:27:0 chr1 10383 . A . . . AN=186;DP=30748 GT:AD:DP:RGQ ./.:22:27:0 chr1 10384 . C . . . AN=308;DP=31997 GT:AD:DP:RGQ 0/0:26:27:33 chr1 10385 . C . . . AN=510;DP=32377 GT:AD:DP:RGQ 0/0:27:27:33 chr1 10386 . C . . . AN=526;DP=31908 GT:AD:DP:RGQ 0/0:27:28:33 chr1 10387 . T C . . AC=0;AF=0;AN=280;BaseQRankSum=0.762;ClippingRankSum=-0.736;DP=30161;ExcessHet=3.01;MQ=0.58;MQRankSum=-0.736;ReadPosRankSum=0.736 GT:AD:DP:RGQ ./.:24,4:28:0 chr1 10388 . A T . . AC=0;AF=0;AN=292;DP=30144;ExcessHet=3.01;MQ=0.47 GT:AD:DP:PGT:PID:RGQ ./.:27,3:30:.:.:0 chr1 10389 . ACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC A,ACCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC,ACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC . . AC=0,0,0;AF=0,0,0;AN=226;BaseQRankSum=0.731;ClippingRankSum=0.731;DP=29603;ExcessHet=3.01;MQ=0.95;MQRankSum=-0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID:RGQ ./.:23,6,6,6:29:.:.:0 chr1 10390 . CCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAA C 1989.61 . AC=18;AF=0.00989;AN=1820;BaseQRankSum=0.736;ClippingRankSum=0.198;DP=31399;ExcessHet=2.14748e+09;FS=27.678;InbreedingCoeff=-0.2628;MLEAC=27;MLEAF=0.015;MQ=3.16;MQRankSum=0.727;QD=15.79;ReadPosRankSum=0.493;SOR=0.437 GT:AD:DP:GQ:PGT:PID:PL 0/0:23,6:29:0:.:.:0,0,612 chr1 10391 . C . . . AN=366;DP=33506 GT:AD:DP:RGQ ./.:26:29:0 chr1 10392 . C . . . AN=528;DP=33928 GT:AD:DP:RGQ 0/0:27:29:36 chr1 10393 . C T . . AC=0;AF=0;AN=406;BaseQRankSum=0.731;ClippingRankSum=-0.731;DP=32877;ExcessHet=3.01;MQ=0.83;MQRankSum=0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID:RGQ ./.:25,3:28:.:.:0 chr1 10394 . T C . . AC=0;AF=0;AN=160;BaseQRankSum=-1.645;ClippingRankSum=0.31;DP=31433;ExcessHet=3.01;MQ=1.24;MQRankSum=0.262;ReadPosRankSum=-2.393 GT:AD:DP:PGT:PID:RGQ ./.:21,7:28:.:.:0 chr1 10395 . A . . . AN=180;DP=32229 GT:AD:DP:RGQ ./.:20:28:0 chr1 10396 . AC A . . AC=0;AF=0;AN=220;BaseQRankSum=0.731;ClippingRankSum=0.731;DP=31887;ExcessHet=3.01;MQ=0.91;MQRankSum=-0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID:RGQ ./.:19,7:26:.:.:0 chr1 10397 . CCCCTAA C 658.74 . AC=8;AF=0.004301;AN=1860;BaseQRankSum=0.736;ClippingRankSum=0.358;DP=33161;ExcessHet=2.14748e+09;FS=14.46;InbreedingCoeff=-0.244;MLEAC=7;MLEAF=0.003763;MQ=2.55;MQRankSum=0.731;QD=9.98;ReadPosRankSum=-0.709;SOR=0.786 GT:AD:DP:GQ:PGT:PID:PL 0/0:21,7:28:0:.:.:0,0,451 chr1 10398 . C G . . AC=0;AF=0;AN=494;DP=35588;ExcessHet=3.01;MQ=0.52 GT:AD:DP:PGT:PID:RGQ 0/0:27,1:28:.:.:27 chr1 10399 . C . . . AN=684;DP=35790 GT:AD:DP:RGQ ./.:26:28:0 chr1 10400 . C T . . AC=0;AF=0;AN=542;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=34991;ExcessHet=3.01;MQ=0.51;MQRankSum=0.736;ReadPosRankSum=0.736 GT:AD:DP:PGT:PID:RGQ ./.:23,4:27:.:.:0 chr1 10401 . TA T . . AC=0;AF=0;AN=384;BaseQRankSum=0.731;ClippingRankSum=0.731;DP=33949;ExcessHet=3.01;MQ=0.39;MQRankSum=-0.731;ReadPosRankSum=0.731 GT:AD:DP:PGT:PID:RGQ ./.:22,5:27:.:.:0 chr1 10402 . A . . . AN=382;DP=34851 GT:AD:DP:RGQ ./.:22:27:0 chr1 10403 . A ACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAAC 2085.08 . AC=6;AF=0.00339;AN=1770;BaseQRankSum=-0.296;ClippingRankSum=0.736;DP=34164;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2531;MLEAC=4;MLEAF=0.00226;MQ=1.08;MQRankSum=1.88;QD=30.09;ReadPosRankSum=-2.27;SOR=1.118 GT:AD:DP:GQ:PL 0/0:24,3:27:10:0,10,557 chr1 10404 . CCCTAA C 107.81 . AC=4;AF=0.002086;AN=1918;BaseQRankSum=0.736;ClippingRankSum=0.736;DP=35988;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2033;MLEAC=9;MLEAF=0.004692;MQ=0.51;MQRankSum=-0.736;QD=13.48;ReadPosRankSum=-0.736;SOR=0.693 GT:AD:DP:GQ:PL 0/0:27,0:27:30:0,30,450 chr1 10405 . C . . . AN=910;DP=36504 GT:AD:DP:RGQ 0/0:27:27:30 chr1 10406 . C . . . AN=842;DP=35903 GT:AD:DP:RGQ 0/0:25:27:30 chr1 10407 . TAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTA CAACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTA,TACCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTA,T . . AC=0,0,0;AF=0,0,0;AN=568;BaseQRankSum=0.358;ClippingRankSum=-0.727;DP=34596;ExcessHet=3.01;MQ=0.79;MQRankSum=0.727;ReadPosRankSum=-0.727 GT:AD:DP:PGT:PID:RGQ ./.:23,4,4,4:27:.:.:0 chr1 10408 . A T . . AC=0;AF=0;AN=512;BaseQRankSum=-0.742;ClippingRankSum=-0.742;DP=35492;ExcessHet=3.01;MQ=0.48;MQRankSum=0.742;ReadPosRankSum=-0.742 GT:AD:DP:PGT:PID:RGQ 0/0:26,1:27:.:.:30 chr1 10409 . A AC 578.59 . AC=4;AF=0.002114;AN=1892;BaseQRankSum=1.03;ClippingRankSum=1.5;DP=34914;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2219;MLEAC=4;MLEAF=0.002114;MQ=0.99;MQRankSum=0.198;QD=31.26;ReadPosRankSum=1.59;SOR=0.569 GT:AD:DP:GQ:PGT:PID:PL 0/0:26,1:27:30:.:.:0,30,450 chr1 10410 . CCCTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAA C,CCCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAA . . AC=0,0;AF=0,0;AN=1044;BaseQRankSum=1.05;ClippingRankSum=0.203;DP=35999;ExcessHet=3.01;MQ=1.92;MQRankSum=0.182;ReadPosRankSum=0.704 GT:AD:DP:RGQ 0/0:27,0,0:27:30 chr1 10411 . C . . . AN=1282;DP=36695 GT:AD:DP:RGQ 0/0:27:27:30 chr1 10412 . C . . . AN=1248;DP=36123 GT:AD:DP:RGQ 0/0:27:27:30 chr1 10413 . T . . . AN=936;DP=34901 GT:AD:DP:RGQ ./.:25:27:0 chr1 10414 . A AACCCT,T . . AC=0,0;AF=0,0;AN=952;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=35709;ExcessHet=3.01;MQ=0.42;MQRankSum=0.727;ReadPosRankSum=-0.727 GT:AD:DP:RGQ 0/0:27,0,0:27:27 chr1 10415 . A G,T,AC,C . . AC=0,0,0,0;AF=0,0,0,0;AN=946;BaseQRankSum=0;ClippingRankSum=-0.348;DP=35278;ExcessHet=3.01;MQ=0.92;MQRankSum=1.39;ReadPosRankSum=1.59 GT:AD:DP:PGT:PID:RGQ 0/0:26,2,2,2,2:28:.:.:30 chr1 10416 . C . . . AN=1346;DP=36248 GT:AD:DP:RGQ 0/0:28:28:30 chr1 10417 . C . . . AN=1494;DP=36738 GT:AD:DP:RGQ 0/0:27:28:30 chr1 10418 . C . . . AN=1570;DP=36165 GT:AD:DP:RGQ 0/0:27:28:30 chr1 10419 . TA CA,T . . AC=0,0;AF=0,0;AN=1440;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=34862;ExcessHet=3.01;MQ=1.26;MQRankSum=-0.572;ReadPosRankSum=0.572 GT:AD:DP:RGQ 0/0:26,2,2:28:25 chr1 10420 . AACCCT A . . AC=0;AF=0;AN=1522;BaseQRankSum=0.392;ClippingRankSum=-0.771;DP=35646;ExcessHet=3.01;MQ=1.77;MQRankSum=0.23;ReadPosRankSum=-1.507 GT:AD:DP:RGQ 0/0:28,0:28:33 chr1 10421 . A AC,G,C,ACC . . AC=0,0,0,0;AF=0,0,0,0;AN=1472;BaseQRankSum=0.067;ClippingRankSum=0.967;DP=35342;ExcessHet=3.01;MQ=1.36;MQRankSum=0.572;ReadPosRankSum=1.61 GT:AD:DP:PGT:PID:RGQ 0/0:26,2,2,2,2:28:.:.:33 chr1 10422 . CCCTAACCCTAA CCCCTAA,GCCTAACCCTAA,C . . AC=0,0,0;AF=0,0,0;AN=1652;BaseQRankSum=-1.537;ClippingRankSum=-0.817;DP=35753;ExcessHet=3.01;MQ=3.1;MQRankSum=-0.72;ReadPosRankSum=-1.38 GT:AD:DP:RGQ 0/0:28,0,0,0:28:27 chr1 10423 . C . . . AN=1838;DP=36352 GT:AD:DP:RGQ 0/0:27:28:27 chr1 10424 . C T . . AC=0;AF=0;AN=1846;BaseQRankSum=-0.751;ClippingRankSum=0.751;DP=35693;ExcessHet=3.01;MQ=0.5;MQRankSum=0.751;ReadPosRankSum=0.751 GT:AD:DP:RGQ ./.:26,3:29:0 chr1 10425 . TA T,CA . . AC=0,0;AF=0,0;AN=1724;BaseQRankSum=0.72;ClippingRankSum=0.034;DP=34437;ExcessHet=3.01;MQ=1.48;MQRankSum=0.849;ReadPosRankSum=1.38 GT:AD:DP:PGT:PID:RGQ ./.:25,4,4:29:.:.:0 chr1 10426 . A G,C . . AC=0,0;AF=0,0;AN=1778;BaseQRankSum=-1.014;ClippingRankSum=-0.986;DP=35076;ExcessHet=3.01;MQ=1.56;MQRankSum=2.14;ReadPosRankSum=0 GT:AD:DP:PGT:PID:RGQ 0/0:29,0,0:29:.:.:18 chr1 10427 . A AC 148.83 . AC=3;AF=0.001558;AN=1926;BaseQRankSum=0.358;ClippingRankSum=0.72;DP=34699;ExcessHet=14.3006;FS=12.438;InbreedingCoeff=-0.0383;MLEAC=3;MLEAF=0.001558;MQ=1.73;MQRankSum=0.572;QD=6.2;ReadPosRankSum=1.23;SOR=0.732 GT:AD:DP:GQ:PGT:PID:PL 0/0:25,1:26:18:.:.:0,18,270 chr1 10428 . CCCTAA C . . AC=0;AF=0;AN=1734;BaseQRankSum=-0.72;ClippingRankSum=-0.72;DP=35022;ExcessHet=3.01;MQ=0.45;MQRankSum=0;ReadPosRankSum=1.38 GT:AD:DP:PGT:PID:RGQ 0/0:27,1:28:.:.:18 chr1 10429 . C G . . AC=0;AF=0;AN=1822;DP=35230;ExcessHet=3.01;MQ=0.75 GT:AD:DP:RGQ 0/0:27,1:28:18 chr1 10430 . C CT . . AC=0;AF=0;AN=1790;DP=34463;ExcessHet=3.01;MQ=0.73 GT:AD:DP:PGT:PID:RGQ ./.:25,3:28:.:.:0 chr1 10431 . TAACCCTA AAACCCTA,TTA,TACCCTA,CAACCCTA,T,GAACCCTA,TAAACCCTA . . AC=0,0,0,0,0,0,0;AF=0,0,0,0,0,0,0;AN=1614;BaseQRankSum=0.447;ClippingRankSum=-0.805;DP=32949;ExcessHet=3.01;MQ=3.07;MQRankSum=0.358;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID:RGQ 0/0:27,1,1,1,1,1,1,1:28:.:.:18 chr1 10432 . AACCCTAAC TACCCTAAC,A,CACCCTAAC . . AC=0,0,0;AF=0,0,0;AN=1700;BaseQRankSum=-0.057;ClippingRankSum=0.964;DP=33492;ExcessHet=3.01;MQ=1.59;MQRankSum=1.27;ReadPosRankSum=-0.587 GT:AD:DP:PGT:PID:RGQ 0/0:27,0,0,0:27:.:.:18 chr1 10433 . ACCCTAAC ACCCCTAAC,A,GCCCTAAC,ACCCTTAACCCCTAAC . . AC=0,0,0,0;AF=0,0,0,0;AN=1450;BaseQRankSum=1.23;ClippingRankSum=-0.358;DP=32963;ExcessHet=3.01;MQ=1.59;MQRankSum=-0.198;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID:RGQ 0/0:25,1,1,1,1:26:.:.:18 chr1 10434 . CCCT C,GCCT . . AC=0,0;AF=0,0;AN=1510;BaseQRankSum=0;ClippingRankSum=0.358;DP=33018;ExcessHet=3.01;MQ=0.61;MQRankSum=-0.358;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID:RGQ 0/0:25,1,1:26:.:.:18 chr1 10435 . C . . . AN=1884;DP=32924 GT:AD:DP:RGQ 0/0:26:26:18 chr1 10436 . C T 298.7 . AC=3;AF=0.001556;AN=1928;BaseQRankSum=-0.742;ClippingRankSum=0.493;DP=31863;ExcessHet=4.1842;FS=1.095;InbreedingCoeff=-0.0166;MLEAC=2;MLEAF=0.001037;MQ=1.51;MQRankSum=0.742;QD=21.34;ReadPosRankSum=-0.358;SOR=0.529 GT:AD:DP:GQ:PGT:PID:PL 0/0:26,0:26:18:.:.:0,18,270 chr1 10437 . TAACCCC GAACCCC,TC,T,CAACCCC,TACCCC . . AC=0,0,0,0,0;AF=0,0,0,0,0;AN=1554;BaseQRankSum=0.742;ClippingRankSum=0.742;DP=30326;ExcessHet=3.01;MQ=1.5;MQRankSum=0.736;ReadPosRankSum=0.804 GT:AD:DP:PGT:PID:RGQ ./.:22,4,4,4,4,4:26:.:.:0 chr1 10438 . AACCCCT TACCCCT,CACCCCT,AGCCCTACCCCT,ACCCT,A . . AC=0,0,0,0,0;AF=0,0,0,0,0;AN=1580;BaseQRankSum=0.067;ClippingRankSum=0.742;DP=30288;ExcessHet=3.01;MQ=1.45;MQRankSum=-0.742;ReadPosRankSum=1.23 GT:AD:DP:PGT:PID:RGQ ./.:20,5,5,5,5,5:25:.:.:0 chr1 10439 . ACC AC,A 62672.6 . AC=286,4;AF=0.149,0.002083;AN=1920;BaseQRankSum=-0.361;ClippingRankSum=0;DP=25898;ExcessHet=0.0065;FS=7.168;InbreedingCoeff=0.1075;MLEAC=273,4;MLEAF=0.142,0.002083;MQ=14.01;MQRankSum=0.358;QD=15.25;ReadPosRankSum=-0.358;SOR=1.287 GT:AD:DP:GQ:PGT:PID:PL 0/0:1,0,0:1:1:.:.:0,1,2,1,2,2 chr1 10440 . C CCCTAACCCTAA,A,CCCTTAA 5329.45 . AC=2,30,1;AF=0.001049,0.016,0.0005247;AN=1906;BaseQRankSum=-0.65;ClippingRankSum=-0.311;DP=28314;ExcessHet=8.2859;FS=0;InbreedingCoeff=0.2661;MLEAC=1,26,1;MLEAF=0.0005247,0.014,0.0005247;MQ=6.3;MQRankSum=0.269;QD=12.54;ReadPosRankSum=0.085;SOR=0.56 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0,0,0:1:.:.:.:. chr1 10441 . CCCTA C 3290.1 . AC=2;AF=0.001094;AN=1828;BaseQRankSum=-0.727;ClippingRankSum=-0.358;DP=28140;ExcessHet=2.14748e+09;FS=0;InbreedingCoeff=-0.2599;MLEAC=2;MLEAF=0.001094;MQ=3.08;MQRankSum=0.343;QD=29;ReadPosRankSum=0.358;SOR=0.69 GT:AD:DP:GQ:PGT:PID:PL 0/0:18,7:25:0:.:.:0,0,449 chr1 10442 . C CT 163.39 . AC=2;AF=0.001205;AN=1660;BaseQRankSum=-0.358;ClippingRankSum=0.731;DP=27104;ExcessHet=30.7241;FS=0;InbreedingCoeff=-0.1081;MLEAC=2;MLEAF=0.001205;MQ=0.87;MQRankSum=-0.589;QD=20.42;ReadPosRankSum=-0.118;SOR=0.446 GT:AD:DP:GQ:PGT:PID:PL 0/0:20,3:23:0:.:.:0,0,572 chr1 10443 . CT TT,C 3668.13 . AC=26,6;AF=0.014,0.003293;AN=1822;BaseQRankSum=-0.736;ClippingRankSum=0;DP=25038;ExcessHet=0.1326;FS=20.792;InbreedingCoeff=0.0924;MLEAC=26,4;MLEAF=0.014,0.002195;MQ=3.82;MQRankSum=0.198;QD=15.1;ReadPosRankSum=0.322;SOR=0.201 GT:AD:DP:GQ:PGT:PID:PL 0/0:17,5,5:22:0:.:.:0,0,392,0,392,392 chr1 10444 . TA AA,T 3350.54 . AC=10,8;AF=0.005537,0.00443;AN=1806;BaseQRankSum=-0.736;ClippingRankSum=0.134;DP=23714;ExcessHet=0.0014;FS=0;InbreedingCoeff=0.1084;MLEAC=8,5;MLEAF=0.00443,0.002769;MQ=2.4;MQRankSum=-0.296;QD=26.28;ReadPosRankSum=-0.668;SOR=0.551 GT:AD:DP:GQ:PGT:PID:PL 0/0:18,4,4:22:0:.:.:0,0,401,0,401,401 chr1 10445 . AACCCT A 234.04 . AC=4;AF=0.002328;AN=1718;BaseQRankSum=-0.736;ClippingRankSum=-0.48;DP=23566;ExcessHet=96.1362;FS=1.559;InbreedingCoeff=-0.1452;MLEAC=4;MLEAF=0.002328;MQ=1.36;MQRankSum=0.736;QD=30.19;ReadPosRankSum=-0.736;SOR=0.384 GT:AD:DP:GQ:PGT:PID:PL 0/0:18,4:22:0:.:.:0,0,490 chr1 10446 . A G 691.48 . AC=2;AF=0.00117;AN=1710;BaseQRankSum=-0.747;ClippingRankSum=0.736;DP=23126;ExcessHet=100.32;FS=1.852;InbreedingCoeff=-0.1482;MLEAC=1;MLEAF=0.0005848;MQ=1.55;MQRankSum=0.747;QD=29.45;ReadPosRankSum=-0.496;SOR=0.307 GT:AD:DP:GQ:PGT:PID:PL 0/0:19,3:22:0:.:.:0,0,448 chr1 10447 . CCCTAA C 313.96 . AC=9;AF=0.0053;AN=1698;BaseQRankSum=0.067;ClippingRankSum=0.406;DP=22835;ExcessHet=16.9094;FS=14.962;InbreedingCoeff=-0.0835;MLEAC=8;MLEAF=0.004711;MQ=2.62;MQRankSum=0.116;QD=11.21;ReadPosRankSum=-0.736;SOR=0.135 GT:AD:DP:GQ:PGT:PID:PL 0/0:19,3:22:0:.:.:0,0,590 chr1 10448 . C A . . AC=0;AF=0;AN=1546;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=22503;ExcessHet=3.01;MQ=0.3;MQRankSum=0.804;ReadPosRankSum=0.804 GT:AD:DP:PGT:PID:RGQ 0/0:21,1:22:.:.:18 chr1 10449 . C CT . . AC=0;AF=0;AN=1406;DP=21657;ExcessHet=3.01;MQ=0.47 GT:AD:DP:PGT:PID:RGQ 0/0:20,1:21:.:.:18 chr1 10450 . T C,G 1389.18 . AC=6,4;AF=0.003401,0.002268;AN=1764;BaseQRankSum=0;ClippingRankSum=0.358;DP=20544;ExcessHet=0.0016;FS=5.379;InbreedingCoeff=0.0886;MLEAC=4,3;MLEAF=0.002268,0.001701;MQ=2.62;MQRankSum=0;QD=34.04;ReadPosRankSum=0.736;SOR=0.341 GT:AD:DP:GQ:PGT:PID:PL 0/0:20,1,1:21:18:.:.:0,18,270,18,270,270 chr1 10451 . A T 782.86 . AC=2;AF=0.001159;AN=1726;BaseQRankSum=-0.731;ClippingRankSum=-0.198;DP=20384;ExcessHet=74.6225;FS=11.805;InbreedingCoeff=-0.1287;MLEAC=2;MLEAF=0.001159;MQ=2.51;MQRankSum=0.198;QD=29.82;ReadPosRankSum=0.727;SOR=0.064 GT:AD:DP:GQ:PGT:PID:PL 0/0:19,2:21:10:.:.:0,10,515 chr1 10452 . A C,G 497.17 . AC=8,2;AF=0.004662,0.001166;AN=1716;BaseQRankSum=-0.747;ClippingRankSum=0.804;DP=19813;ExcessHet=0;FS=4.961;InbreedingCoeff=0.0888;MLEAC=5,1;MLEAF=0.002914,0.0005828;MQ=1.57;MQRankSum=0.804;QD=19.89;ReadPosRankSum=0.804;SOR=0.148 GT:AD:DP:GQ:PGT:PID:PL 0/0:19,2,2:21:4:.:.:0,4,508,4,508,508 chr1 10453 . CCCTAA C,GCCTAA,ACCTAA . . AC=0,0,0;AF=0,0,0;AN=1434;BaseQRankSum=-0.736;ClippingRankSum=0.736;DP=19420;ExcessHet=3.01;MQ=2.66;MQRankSum=0.482;ReadPosRankSum=0 GT:AD:DP:PGT:PID:RGQ 0/0:19,0,0,0:19:.:.:18 chr1 10454 . C T . . AC=0;AF=0;AN=1534;BaseQRankSum=-1.041;ClippingRankSum=-1.561;DP=19102;ExcessHet=3.01;MQ=0.92;MQRankSum=0.173;ReadPosRankSum=-1.041 GT:AD:DP:RGQ 0/0:19,0:19:18 chr1 10455 . C A . . AC=0;AF=0;AN=1512;BaseQRankSum=-1.666;ClippingRankSum=0.067;DP=18360;ExcessHet=3.01;MQ=0.47;MQRankSum=0.762;ReadPosRankSum=0.067 GT:AD:DP:PGT:PID:RGQ 0/0:19,0:19:.:.:18 chr1 10456 . T C,TG . . AC=0,0;AF=0,0;AN=1214;BaseQRankSum=-1.739;ClippingRankSum=0.158;DP=17536;ExcessHet=3.01;MQ=2.14;MQRankSum=0.791;ReadPosRankSum=-1.739 GT:AD:DP:PGT:PID:RGQ 0/0:18,0,0:18:.:.:18 chr1 10457 . A T 429.49 . AC=4;AF=0.002317;AN=1726;BaseQRankSum=-0.736;ClippingRankSum=0;DP=17125;ExcessHet=42.053;FS=4.627;InbreedingCoeff=-0.1057;MLEAC=3;MLEAF=0.001738;MQ=1.44;MQRankSum=0.736;QD=33.74;ReadPosRankSum=0.198;SOR=0.162 GT:AD:DP:GQ:PGT:PID:PL 0/0:18,0:18:18:.:.:0,18,270 chr1 10458 . A . . . AN=1320;DP=16611 GT:AD:DP:RGQ 0/0:17:18:18 chr1 10459 . C A 33.68 . AC=1;AF=0.0005869;AN=1704;BaseQRankSum=-0.736;ClippingRankSum=-0.736;DP=16189;ExcessHet=27.4097;FS=0;InbreedingCoeff=-0.0919;MLEAC=1;MLEAF=0.0005869;MQ=0.39;MQRankSum=-0.736;QD=11.23;ReadPosRankSum=-0.736;SOR=0.223 GT:AD:DP:GQ:PGT:PID:PL 0/0:15,2:17:0:.:.:0,0,421 chr1 10460 . C G . . AC=0;AF=0;AN=1560;BaseQRankSum=-1.026;ClippingRankSum=-1.026;DP=15729;ExcessHet=3.01;MQ=0.35;MQRankSum=-1.026;ReadPosRankSum=-1.026 GT:AD:DP:PGT:PID:RGQ 0/0:15,0:15:.:.:18 chr1 10461 . C CT,T . . AC=0,0;AF=0,0;AN=1514;BaseQRankSum=-1.387;ClippingRankSum=0;DP=14975;ExcessHet=3.01;MQ=1.64;MQRankSum=-0.572;ReadPosRankSum=0 GT:AD:DP:PGT:PID:RGQ 0/0:13,1,1:14:.:.:10 chr1 10462 . T G,C . . AC=0,0;AF=0,0;AN=1124;BaseQRankSum=-1.231;ClippingRankSum=0.358;DP=14079;ExcessHet=3.01;MQ=1.16;MQRankSum=-0.358;ReadPosRankSum=-0.727 GT:AD:DP:PGT:PID:RGQ 0/0:11,1,1:12:.:.:11 chr1 10463 . AACCCTCGCGGT A . . AC=0;AF=0;AN=1164;DP=13304;ExcessHet=3.01;MQ=1.2 GT:AD:DP:PGT:PID:RGQ 0/0:10,1:11:.:.:8 chr1 10464 . A . . . AN=1378;DP=12317 GT:AD:DP:RGQ 0/0:9:9:18 chr1 10465 . CCCTCGCGGTA CCGCGGTA,C . . AC=0,0;AF=0,0;AN=1356;DP=11631;ExcessHet=3.01;MQ=1.34 GT:AD:DP:PGT:PID:RGQ ./.:9,1,1:10:.:.:0 chr1 10466 . C T . . AC=0;AF=0;AN=1462;DP=10700;ExcessHet=3.01;MQ=0.87 GT:AD:DP:PGT:PID:RGQ 0/0:10,0:10:.:.:18 chr1 10467 . CTCGCGG C 91.48 . AC=1;AF=0.0005754;AN=1738;BaseQRankSum=0.839;ClippingRankSum=-0.71;DP=9660;ExcessHet=17.792;FS=15.091;InbreedingCoeff=-0.09;MLEAC=1;MLEAF=0.0005754;MQ=1.82;MQRankSum=-1.097;QD=6.53;ReadPosRankSum=-2.905;SOR=3.901 GT:AD:DP:GQ:PGT:PID:PL 0/0:9,0:9:18:.:.:0,18,270 chr1 10468 . T TAACCCTAACCCTAACCCCTAACCC 2053.01 . AC=2;AF=0.001153;AN=1734;BaseQRankSum=0.736;ClippingRankSum=0.358;DP=8545;ExcessHet=72.7396;FS=0;InbreedingCoeff=-0.1633;MLEAC=1;MLEAF=0.0005767;MQ=4.39;MQRankSum=-0.347;QD=33.93;ReadPosRankSum=-1.231;SOR=0.872 GT:AD:DP:GQ:PGT:PID:PL 0/0:8,1:9:0:.:.:0,0,193 chr1 10469 . C G 46.14 . AC=1;AF=0.0007899;AN=1266;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=7714;ExcessHet=95.6797;FS=3.522;InbreedingCoeff=-0.239;MLEAC=5;MLEAF=0.003949;MQ=1.42;MQRankSum=0.736;QD=15.38;ReadPosRankSum=0.736;SOR=2.272 GT:AD:DP:GQ:PGT:PID:PL 0/0:5,2:7:0:.:.:0,0,72 chr1 10470 . G C . . AC=0;AF=0;AN=446;BaseQRankSum=2.33;ClippingRankSum=-0.454;DP=6910;ExcessHet=3.01;MQ=2.89;MQRankSum=1.46;ReadPosRankSum=-0.298 GT:AD:DP:PGT:PID:RGQ ./.:6,1:7:.:.:0 chr1 10471 . CGG C . . AC=0;AF=0;AN=1054;BaseQRankSum=1.51;ClippingRankSum=0.736;DP=6649;ExcessHet=3.01;MQ=2.88;MQRankSum=0.892;ReadPosRankSum=-0.736 GT:AD:DP:PGT:PID:RGQ ./.:6,1:7:.:.:0 chr1 10472 . G . . . AN=696;DP=6122 GT:AD:DP:RGQ ./.:6:7:0 chr1 10473 . G A 137.73 . AC=5;AF=0.003338;AN=1498;BaseQRankSum=2.05;ClippingRankSum=1.47;DP=6021;ExcessHet=32.8816;FS=1.489;InbreedingCoeff=-0.1331;MLEAC=8;MLEAF=0.00534;MQ=2.47;MQRankSum=0.906;QD=4.17;ReadPosRankSum=1.47;SOR=0.709 GT:AD:DP:GQ:PL 0/0:6,0:6:18:0,18,171 chr1 10474 . T A,TA,TAACCCCTAACCCTA,TAACCCTAACCCTA . . AC=0,0,0,0;AF=0,0,0,0;AN=1030;BaseQRankSum=0.742;ClippingRankSum=-0.736;DP=5833;ExcessHet=3.01;MQ=4.21;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:PGT:PID:RGQ 0/0:6,0,0,0,0:6:.:.:18 chr1 10475 . A AAC 93.58 . AC=1;AF=0.0006083;AN=1644;BaseQRankSum=1.49;ClippingRankSum=0.968;DP=5720;ExcessHet=18.9519;FS=15.091;InbreedingCoeff=-0.113;MLEAC=1;MLEAF=0.0006083;MQ=2.19;MQRankSum=-0.452;QD=6.68;ReadPosRankSum=-0.751;SOR=3.901 GT:AD:DP:GQ:PGT:PID:PL 0/0:6,0:6:18:.:.:0,18,182 chr1 10476 . C A . . AC=0;AF=0;AN=1116;BaseQRankSum=-1.423;ClippingRankSum=-1.423;DP=5735;ExcessHet=3.01;MQ=1.82;MQRankSum=-0.474 GT:AD:DP:PGT:PID:RGQ 0/0:6,0:6:.:.:18 chr1 10477 . C . . . AN=1304;DP=5822 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10478 . C . . . AN=1434;DP=5712 GT:AD:DP:RGQ 0/0:6:6:17 chr1 10479 . T . . . AN=1096;DP=5373 GT:AD:DP:RGQ 0/0:6:6:17 chr1 10480 . C A . . AC=0;AF=0;AN=1440;BaseQRankSum=0.751;ClippingRankSum=0.751;DP=5515;ExcessHet=3.01;MQ=3.5;MQRankSum=0.272;ReadPosRankSum=-0.751 GT:AD:DP:PGT:PID:RGQ 0/0:6,0:6:.:.:17 chr1 10481 . A . . . AN=1304;DP=5354 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10482 . G C . . AC=0;AF=0;AN=1290;BaseQRankSum=-0.751;ClippingRankSum=0.421;DP=5306;ExcessHet=3.01;MQ=3.35;MQRankSum=0.299;ReadPosRankSum=-2.793 GT:AD:DP:PGT:PID:RGQ 0/0:6,0:6:.:.:18 chr1 10483 . C A . . AC=0;AF=0;AN=1478;BaseQRankSum=1.03;ClippingRankSum=0;DP=5438;ExcessHet=3.01;MQ=0.8;MQRankSum=1.03;ReadPosRankSum=1.03 GT:AD:DP:RGQ 0/0:6,0:6:17 chr1 10484 . C . . . AN=1550;DP=5374 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10485 . G . . . AN=1338;DP=5163 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10486 . G . . . AN=1392;DP=5096 GT:AD:DP:RGQ 0/0:6:6:17 chr1 10487 . C . . . AN=1536;DP=5208 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10488 . C . . . AN=1524;DP=5178 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10489 . C . . . AN=1550;DP=5167 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10490 . G . . . AN=1468;DP=4945 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10491 . C . . . AN=1618;DP=5095 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10492 . C T 924.66 . AC=32;AF=0.02;AN=1598;BaseQRankSum=-0.358;ClippingRankSum=-0.198;DP=5075;ExcessHet=0.0046;FS=0.671;InbreedingCoeff=-0.015;MLEAC=34;MLEAF=0.021;MQ=4.44;MQRankSum=0.358;QD=7.28;ReadPosRankSum=0;SOR=0.592 GT:AD:DP:GQ:PGT:PID:PL 0/0:6,0:6:18:.:.:0,18,167 chr1 10493 . C . . . AN=1578;DP=5035 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10494 . G . . . AN=1494;DP=4852 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10495 . C . . . AN=1572;DP=4936 GT:AD:DP:RGQ 0/0:6:6:18 chr1 10496 . C . . . AN=1624;DP=4947 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10497 . C T . . AC=0;AF=0;AN=1620;DP=4915;ExcessHet=3.01;MQ=0.42 GT:AD:DP:RGQ 0/0:6,0:6:12 chr1 10498 . G T . . AC=0;AF=0;AN=1556;DP=4804;ExcessHet=3.01;MQ=0.68 GT:AD:DP:RGQ 0/0:6,0:6:12 chr1 10499 . G . . . AN=1570;DP=4780 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10500 . G . . . AN=1578;DP=4732 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10501 . T . . . AN=1370;DP=4438 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10502 . C . . . AN=1610;DP=4748 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10503 . T C . . AC=0;AF=0;AN=1492;BaseQRankSum=1.23;ClippingRankSum=0.358;DP=4545;ExcessHet=3.01;MQ=0.79;MQRankSum=0.358;ReadPosRankSum=0.358 GT:AD:DP:PGT:PID:RGQ 0/0:6,0:6:.:.:12 chr1 10504 . G C 52.81 . AC=1;AF=0.000601;AN=1664;BaseQRankSum=0.727;ClippingRankSum=0.727;DP=4606;ExcessHet=3.4244;FS=0;InbreedingCoeff=-0.0614;MLEAC=1;MLEAF=0.000601;MQ=0.97;MQRankSum=0.727;QD=13.2;ReadPosRankSum=0.727;SOR=1.609 GT:AD:DP:GQ:PL 0/0:6,0:6:12:0,12,180 chr1 10505 . A . . . AN=1534;DP=4492 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10506 . C . . . AN=1628;DP=4589 GT:AD:DP:RGQ 0/0:6:6:12 chr1 10507 . C . . . AN=1610;DP=4559 GT:AD:DP:RGQ 0/0:5:5:12 chr1 10508 . T . . . AN=1428;DP=4323 GT:AD:DP:RGQ 0/0:4:4:12 chr1 10509 . G . . . AN=1574;DP=4454 GT:AD:DP:RGQ 0/0:4:4:12 chr1 10510 . A . . . AN=1540;DP=4381 GT:AD:DP:RGQ 0/0:4:4:12 chr1 10511 . G . . . AN=1596;DP=4409 GT:AD:DP:RGQ 0/0:4:4:12 chr1 10512 . G . . . AN=1602;DP=4414 GT:AD:DP:RGQ 0/0:4:4:12 chr1 10513 . A . . . AN=1512;DP=4266 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10514 . G . . . AN=1594;DP=4340 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10515 . A . . . AN=1480;DP=4213 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10516 . A . . . AN=1556;DP=4285 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10517 . C . . . AN=1622;DP=4272 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10518 . T . . . AN=1478;DP=4143 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10519 . G . . . AN=1526;DP=4202 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10520 . T . . . AN=1540;DP=4132 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10521 . G . . . AN=1604;DP=4133 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10522 . C . . . AN=1616;DP=4178 GT:AD:DP:RGQ 0/0:4:4:9 chr1 10523 . T . . . AN=1546;DP=4076 GT:AD:DP:RGQ 0/0:3:3:9 chr1 10524 . C . . . AN=1592;DP=4113 GT:AD:DP:RGQ 0/0:3:3:9 chr1 10525 . C . . . AN=1602;DP=4139 GT:AD:DP:RGQ 0/0:3:3:9 chr1 10526 . G . . . AN=1576;DP=4034 GT:AD:DP:RGQ 0/0:3:3:9 chr1 10527 . C . . . AN=1594;DP=4054 GT:AD:DP:RGQ 0/0:3:3:9 chr1 10528 . C . . . AN=1590;DP=4047 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10529 . T . . . AN=1524;DP=3967 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10530 . T . . . AN=1534;DP=3948 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10531 . C . . . AN=1610;DP=3971 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10532 . A . . . AN=1484;DP=3857 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10533 . G . . . AN=1488;DP=3853 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10534 . A . . . AN=1532;DP=3811 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10535 . G . . . AN=1592;DP=3810 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10536 . T . . . AN=1452;DP=3709 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10537 . A . . . AN=1546;DP=3718 GT:AD:DP:RGQ 0/0:3:3:6 chr1 10538 . C . . . AN=1622;DP=3764 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10539 . C . . . AN=1618;DP=3726 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10540 . A . . . AN=1520;DP=3634 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10541 . C . . . AN=1616;DP=3670 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10542 . C T . . AC=0;AF=0;AN=1556;BaseQRankSum=1.03;ClippingRankSum=-1.026;DP=3668;ExcessHet=3.01;MQ=0.69;MQRankSum=-1.026;ReadPosRankSum=-1.026 GT:AD:DP:RGQ 0/0:2,0:2:6 chr1 10543 . G A 47.93 . AC=2;AF=0.00122;AN=1640;DP=3590;ExcessHet=0.0374;FS=0;InbreedingCoeff=-0.0556;MLEAC=1;MLEAF=0.0006098;MQ=1.03;QD=15.98;SOR=2.833 GT:AD:DP:GQ:PL 0/0:2,0:2:6:0,6,90 chr1 10544 . A . . . AN=1570;DP=3548 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10545 . A . . . AN=1556;DP=3552 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10546 . A . . . AN=1536;DP=3509 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10547 . T . . . AN=1488;DP=3456 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10548 . C . . . AN=1622;DP=3500 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10549 . T . . . AN=1406;DP=3391 GT:AD:DP:RGQ 0/0:2:2:5 chr1 10550 . G . . . AN=1606;DP=3429 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10551 . T . . . AN=1446;DP=3342 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10552 . G . . . AN=1606;DP=3357 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10553 . C . . . AN=1598;DP=3346 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10554 . A . . . AN=1496;DP=3290 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10555 . G . . . AN=1598;DP=3269 GT:AD:DP:RGQ 0/0:2:2:6 chr1 10556 . A . . . AN=1504;DP=3232 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10557 . G . . . AN=1586;DP=3223 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10558 . G C . . AC=0;AF=0;AN=1574;DP=3196;ExcessHet=3.01;MQ=0.53 GT:AD:DP:RGQ 0/0:2,0:2:3 chr1 10559 . A . . . AN=1466;DP=3127 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10560 . C . . . AN=1544;DP=3122 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10561 . A . . . AN=1516;DP=3092 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10562 . A . . . AN=1514;DP=3029 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10563 . C . . . AN=1560;DP=3005 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10564 . G . . . AN=1554;DP=2957 GT:AD:DP:RGQ 0/0:2:2:3 chr1 10565 . C T . . AC=0;AF=0;AN=1542;BaseQRankSum=0.922;ClippingRankSum=-0.922;DP=2938;ExcessHet=3.01;MQ=1.07;MQRankSum=1.5;ReadPosRankSum=0.922 GT:AD:DP:RGQ 0/0:2,0:2:3 chr1 10566 . A . . . AN=1482;DP=2887 GT:AD:DP:RGQ 0/0:1:1:3 chr1 10567 . G . . . AN=1538;DP=2852 GT:AD:DP:RGQ ./.:1:1:0 chr1 10568 . C . . . AN=1536;DP=2825 GT:AD:DP:RGQ ./.:1:1:0 chr1 10569 . T . . . AN=1374;DP=2735 GT:AD:DP:RGQ ./.:1:1:0 chr1 10570 . C A . . AC=0;AF=0;AN=1530;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=2756;ExcessHet=3.01;MQ=1.01;MQRankSum=-0.736;ReadPosRankSum=0.736 GT:AD:DP:RGQ ./.:1,0:1:0 chr1 10571 . C . . . AN=1534;DP=2715 GT:AD:DP:RGQ ./.:1:1:0 chr1 10572 . G . . . AN=1510;DP=2681 GT:AD:DP:RGQ ./.:1:1:0 chr1 10573 . C . . . AN=1540;DP=2643 GT:AD:DP:RGQ ./.:1:1:0 chr1 10574 . C . . . AN=1520;DP=2638 GT:AD:DP:RGQ ./.:1:1:0 chr1 10575 . C . . . AN=1514;DP=2615 GT:AD:DP:RGQ ./.:1:1:0 chr1 10576 . T . . . AN=1338;DP=2546 GT:AD:DP:RGQ ./.:1:1:0 chr1 10577 . C . . . AN=1518;DP=2560 GT:AD:DP:RGQ ./.:0:0:0 chr1 10578 . G . . . AN=1426;DP=2516 GT:AD:DP:RGQ ./.:0:0:0 chr1 10579 . C . . . AN=1484;DP=2512 GT:AD:DP:RGQ ./.:0:0:0 chr1 10580 . G . . . AN=1484;DP=2479 GT:AD:DP:RGQ ./.:0:0:0 chr1 10581 . G . . . AN=1478;DP=2471 GT:AD:DP:RGQ ./.:0:0:0 chr1 10582 . T . . . AN=1336;DP=2434 GT:AD:DP:RGQ ./.:0:0:0 chr1 10583 . G . . . AN=1298;DP=2434 GT:AD:DP:RGQ ./.:0:0:0 chr1 10584 . C . . . AN=1478;DP=2417 GT:AD:DP:RGQ ./.:0:0:0 chr1 10585 . T . . . AN=1292;DP=2370 GT:AD:DP:RGQ ./.:0:0:0 chr1 10586 . C . . . AN=1482;DP=2402 GT:AD:DP:RGQ ./.:0:0:0 chr1 10587 . T . . . AN=1316;DP=2367 GT:AD:DP:RGQ ./.:0:0:0 chr1 10588 . C . . . AN=1466;DP=2366 GT:AD:DP:RGQ ./.:0:0:0 chr1 10589 . C . . . AN=1430;DP=2344 GT:AD:DP:RGQ ./.:0:0:0 chr1 10590 . G . . . AN=1432;DP=2286 GT:AD:DP:RGQ ./.:0:0:0 chr1 10591 . G . . . AN=1400;DP=2253 GT:AD:DP:RGQ ./.:0:0:0 chr1 10592 . G . . . AN=1432;DP=2238 GT:AD:DP:RGQ ./.:0:0:0 chr1 10593 . T . . . AN=1200;DP=2194 GT:AD:DP:RGQ ./.:0:0:0 chr1 10594 . C . . . AN=1424;DP=2198 GT:AD:DP:RGQ ./.:0:0:0 chr1 10595 . T . . . AN=1264;DP=2153 GT:AD:DP:RGQ ./.:0:0:0 chr1 10596 . G . . . AN=1382;DP=2142 GT:AD:DP:RGQ ./.:0:0:0 chr1 10597 . T . . . AN=1242;DP=2115 GT:AD:DP:RGQ ./.:0:0:0 chr1 10598 . G . . . AN=1380;DP=2093 GT:AD:DP:RGQ ./.:0:0:0 chr1 10599 . C . . . AN=1344;DP=2044 GT:AD:DP:RGQ ./.:0:0:0 chr1 10600 . T . . . AN=1172;DP=2012 GT:AD:DP:RGQ ./.:0:0:0 chr1 10601 . G . . . AN=1354;DP=2005 GT:AD:DP:RGQ ./.:0:0:0 chr1 10602 . A . . . AN=1230;DP=1962 GT:AD:DP:RGQ ./.:0:0:0 chr1 10603 . G . . . AN=1348;DP=1953 GT:AD:DP:RGQ ./.:0:0:0 chr1 10604 . G . . . AN=1338;DP=1924 GT:AD:DP:RGQ ./.:0:0:0 chr1 10605 . A . . . AN=1252;DP=1885 GT:AD:DP:RGQ ./.:0:0:0 chr1 10606 . G . . . AN=1302;DP=1868 GT:AD:DP:RGQ ./.:0:0:0 chr1 10607 . A . . . AN=1178;DP=1835 GT:AD:DP:RGQ ./.:0:0:0 chr1 10608 . A . . . AN=1192;DP=1808 GT:AD:DP:RGQ ./.:0:0:0 chr1 10609 . C . . . AN=1188;DP=1783 GT:AD:DP:RGQ ./.:0:0:0 chr1 10610 . G . . . AN=1196;DP=1760 GT:AD:DP:RGQ ./.:0:0:0 chr1 10611 . C G 1132.4 . AC=20;AF=0.045;AN=446;BaseQRankSum=0.742;ClippingRankSum=0.742;DP=1730;ExcessHet=0;FS=14.914;InbreedingCoeff=-0.0127;MLEAC=30;MLEAF=0.067;MQ=3.58;MQRankSum=0.742;QD=30.61;ReadPosRankSum=0.742;SOR=7.327 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 10612 . A . . . AN=950;DP=1714 GT:AD:DP:RGQ ./.:0:0:0 chr1 10613 . A . . . AN=856;DP=1704 GT:AD:DP:RGQ ./.:0:0:0 chr1 10614 . C . . . AN=878;DP=1689 GT:AD:DP:RGQ ./.:0:0:0 chr1 10615 . T . . . AN=828;DP=1657 GT:AD:DP:RGQ ./.:0:0:0 chr1 10616 . CCGCCGTTGCAAAGGCGCGCCG C 252.77 . AC=7;AF=0.007692;AN=910;BaseQRankSum=1.23;ClippingRankSum=0.358;DP=1618;ExcessHet=0;FS=13.222;InbreedingCoeff=-0.0961;MLEAC=6;MLEAF=0.006593;MQ=2.49;MQRankSum=-0.358;QD=19.44;ReadPosRankSum=-1.026;SOR=3.221 GT:AD:DP:GQ:PL ./.:0,0:0:.:. chr1 10617 . C . . . AN=892;DP=1592 GT:AD:DP:RGQ ./.:0:0:0 chr1 10618 . G . . . AN=866;DP=1535 GT:AD:DP:RGQ ./.:0:0:0 chr1 10619 . C . . . AN=866;DP=1504 GT:AD:DP:RGQ ./.:0:0:0 chr1 10620 . C . . . AN=884;DP=1493 GT:AD:DP:RGQ ./.:0:0:0 chr1 10621 . G . . . AN=878;DP=1445 GT:AD:DP:RGQ ./.:0:0:0 chr1 10622 . T G 70.94 . AC=6;AF=0.007042;AN=852;DP=1408;ExcessHet=0.0004;FS=0;InbreedingCoeff=-0.1312;MLEAC=6;MLEAF=0.007042;MQ=1.45;QD=33.49;SOR=1.609 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 10623 . T C 1056.23 . AC=10;AF=0.161;AN=62;DP=1385;ExcessHet=0.0001;FS=0;InbreedingCoeff=0.2163;MLEAC=15;MLEAF=0.242;MQ=2.9;QD=33.07;SOR=4.255 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 10624 . G . . . AN=868;DP=1377 GT:AD:DP:RGQ ./.:0:0:0 chr1 10625 . C . . . AN=846;DP=1378 GT:AD:DP:RGQ ./.:0:0:0 chr1 10626 . A . . . AN=854;DP=1399 GT:AD:DP:RGQ ./.:0:0:0 chr1 10627 . A . . . AN=562;DP=1463 GT:AD:DP:RGQ ./.:0:0:0 chr1 10628 . A . . . AN=718;DP=1466 GT:AD:DP:RGQ ./.:0:0:0 chr1 10629 . G . . . AN=796;DP=1562 GT:AD:DP:RGQ ./.:0:0:0 chr1 10630 . G . . . AN=834;DP=1635 GT:AD:DP:RGQ ./.:0:0:0 chr1 10631 . C . . . AN=762;DP=1686 GT:AD:DP:RGQ ./.:0:0:0 chr1 10632 . G . . . AN=746;DP=1769 GT:AD:DP:RGQ ./.:0:0:0 chr1 10633 . C . . . AN=982;DP=1875 GT:AD:DP:RGQ ./.:0:0:0 chr1 10634 . G . . . AN=1042;DP=1978 GT:AD:DP:RGQ ./.:0:0:0 chr1 10635 . C . . . AN=1094;DP=2055 GT:AD:DP:RGQ ./.:0:0:0 chr1 10636 . C . . . AN=976;DP=2137 GT:AD:DP:RGQ ./.:0:0:0 chr1 10637 . G . . . AN=1106;DP=2271 GT:AD:DP:RGQ ./.:0:0:0 chr1 10638 . C . . . AN=1172;DP=2307 GT:AD:DP:RGQ ./.:0:0:0 chr1 10639 . G . . . AN=942;DP=2412 GT:AD:DP:RGQ ./.:0:0:0 chr1 10640 . C . . . AN=1080;DP=2475 GT:AD:DP:RGQ ./.:0:0:0 chr1 10641 . C . . . AN=940;DP=2554 GT:AD:DP:RGQ ./.:0:0:0 chr1 10642 . G . . . AN=1208;DP=2654 GT:AD:DP:RGQ ./.:0:0:0 chr1 10643 . G . . . AN=1236;DP=2722 GT:AD:DP:RGQ ./.:0:0:0 chr1 10644 . C . . . AN=1260;DP=2810 GT:AD:DP:RGQ ./.:0:0:0 chr1 10645 . G . . . AN=1228;DP=2926 GT:AD:DP:RGQ ./.:0:0:0 chr1 10646 . C . . . AN=1150;DP=3003 GT:AD:DP:RGQ ./.:0:0:0 chr1 10647 . A . . . AN=1036;DP=2968 GT:AD:DP:RGQ ./.:0:0:0 chr1 10648 . G . . . AN=1266;DP=3128 GT:AD:DP:RGQ ./.:0:0:0 chr1 10649 . G . . . AN=1154;DP=3168 GT:AD:DP:RGQ ./.:0:0:0 chr1 10650 . C . . . AN=1274;DP=3207 GT:AD:DP:RGQ ./.:0:0:0 chr1 10651 . G . . . AN=1286;DP=3280 GT:AD:DP:RGQ ./.:0:0:0 chr1 10652 . C . . . AN=1212;DP=3314 GT:AD:DP:RGQ ./.:0:0:0 chr1 10653 . A . . . AN=1192;DP=3298 GT:AD:DP:RGQ ./.:0:0:0 chr1 10654 . G . . . AN=1216;DP=3364 GT:AD:DP:RGQ ./.:0:0:0 chr1 10655 . A . . . AN=1132;DP=3320 GT:AD:DP:RGQ ./.:0:0:0 chr1 10656 . G . . . AN=1264;DP=3419 GT:AD:DP:RGQ ./.:0:0:0 chr1 10657 . A . . . AN=1006;DP=3309 GT:AD:DP:RGQ ./.:0:0:0 chr1 10658 . G . . . AN=1230;DP=3407 GT:AD:DP:RGQ ./.:0:0:0 chr1 10659 . G . . . AN=1222;DP=3437 GT:AD:DP:RGQ ./.:0:0:0 chr1 10660 . C . . . AN=1084;DP=3434 GT:AD:DP:RGQ ./.:0:0:0 chr1 10661 . G . . . AN=1140;DP=3470 GT:AD:DP:RGQ ./.:0:0:0 chr1 10662 . C . . . AN=1218;DP=3483 GT:AD:DP:RGQ ./.:0:0:0 chr1 10663 . G . . . AN=1268;DP=3499 GT:AD:DP:RGQ ./.:0:0:0 chr1 10664 . C . . . AN=1276;DP=3508 GT:AD:DP:RGQ ./.:0:0:0 chr1 10665 . C . . . AN=1258;DP=3515 GT:AD:DP:RGQ ./.:0:0:0 chr1 10666 . G . . . AN=1248;DP=3541 GT:AD:DP:RGQ ./.:0:0:0 chr1 10667 . C . . . AN=1222;DP=3549 GT:AD:DP:RGQ ./.:0:0:0 chr1 10668 . G . . . AN=1170;DP=3591 GT:AD:DP:RGQ ./.:0:0:0 chr1 10669 . C . . . AN=1196;DP=3587 GT:AD:DP:RGQ ./.:0:0:0 chr1 10670 . C . . . AN=1140;DP=3583 GT:AD:DP:RGQ ./.:0:0:0 chr1 10671 . G . . . AN=1252;DP=3626 GT:AD:DP:RGQ ./.:0:0:0 chr1 10672 . G . . . AN=1266;DP=3638 GT:AD:DP:RGQ ./.:0:0:0 chr1 10673 . C . . . AN=1276;DP=3655 GT:AD:DP:RGQ ./.:0:0:0 chr1 10674 . G . . . AN=1270;DP=3684 GT:AD:DP:RGQ ./.:0:0:0 chr1 10675 . C . . . AN=1250;DP=3713 GT:AD:DP:RGQ ./.:0:0:0 chr1 10676 . A . . . AN=972;DP=3609 GT:AD:DP:RGQ ./.:0:0:0 chr1 10677 . G . . . AN=1268;DP=3759 GT:AD:DP:RGQ ./.:0:0:0 chr1 10678 . G . . . AN=1128;DP=3762 GT:AD:DP:RGQ ./.:0:0:0 chr1 10679 . C . . . AN=1258;DP=3745 GT:AD:DP:RGQ ./.:0:0:0 chr1 10680 . G . . . AN=1276;DP=3807 GT:AD:DP:RGQ ./.:0:0:0 chr1 10681 . C . . . AN=1248;DP=3811 GT:AD:DP:RGQ ./.:0:0:0 chr1 10682 . A . . . AN=1144;DP=3723 GT:AD:DP:RGQ ./.:0:0:0 chr1 10683 . G . . . AN=1244;DP=3852 GT:AD:DP:RGQ ./.:0:0:0 chr1 10684 . A . . . AN=1160;DP=3713 GT:AD:DP:RGQ ./.:0:0:0 chr1 10685 . G . . . AN=1244;DP=3855 GT:AD:DP:RGQ ./.:0:0:0 chr1 10686 . A . . . AN=1002;DP=3661 GT:AD:DP:RGQ ./.:0:0:0 chr1 10687 . G . . . AN=1166;DP=3821 GT:AD:DP:RGQ ./.:0:0:0 chr1 10688 . G . . . AN=1232;DP=3881 GT:AD:DP:RGQ ./.:0:0:0 chr1 10689 . C . . . AN=1150;DP=3877 GT:AD:DP:RGQ ./.:0:0:0 chr1 10690 . G . . . AN=1240;DP=3897 GT:AD:DP:RGQ ./.:0:0:0 chr1 10691 . C . . . AN=1188;DP=3906 GT:AD:DP:RGQ ./.:0:0:0 chr1 10692 . G . . . AN=1268;DP=3928 GT:AD:DP:RGQ ./.:0:0:0 chr1 10693 . C . . . AN=1262;DP=3913 GT:AD:DP:RGQ ./.:0:0:0 chr1 10694 . C . . . AN=1236;DP=3928 GT:AD:DP:RGQ ./.:0:0:0 chr1 10695 . G . . . AN=1264;DP=3944 GT:AD:DP:RGQ ./.:0:0:0 chr1 10696 . C . . . AN=1178;DP=3943 GT:AD:DP:RGQ ./.:0:0:0 chr1 10697 . G . . . AN=1234;DP=3968 GT:AD:DP:RGQ ./.:0:0:0 chr1 10698 . C . . . AN=1224;DP=3970 GT:AD:DP:RGQ ./.:0:0:0 chr1 10699 . C . . . AN=1264;DP=3974 GT:AD:DP:RGQ ./.:0:0:0 chr1 10700 . G . . . AN=1284;DP=4002 GT:AD:DP:RGQ ./.:0:0:0 chr1 10701 . G . . . AN=1288;DP=4030 GT:AD:DP:RGQ ./.:0:0:0 chr1 10702 . C . . . AN=1284;DP=4030 GT:AD:DP:RGQ ./.:0:0:0 chr1 10703 . G . . . AN=1296;DP=4065 GT:AD:DP:RGQ ./.:0:0:0 chr1 10704 . C . . . AN=1254;DP=4051 GT:AD:DP:RGQ ./.:0:0:0 chr1 10705 . A . . . AN=1074;DP=3952 GT:AD:DP:RGQ ./.:0:0:0 chr1 10706 . G . . . AN=1300;DP=4068 GT:AD:DP:RGQ ./.:0:0:0 chr1 10707 . G . . . AN=1282;DP=4078 GT:AD:DP:RGQ ./.:0:0:0 chr1 10708 . C . . . AN=1286;DP=4084 GT:AD:DP:RGQ ./.:0:0:0 chr1 10709 . G . . . AN=1312;DP=4102 GT:AD:DP:RGQ ./.:0:0:0 chr1 10710 . C . . . AN=1300;DP=4097 GT:AD:DP:RGQ ./.:0:0:0 chr1 10711 . A . . . AN=1142;DP=3993 GT:AD:DP:RGQ ./.:0:0:0 chr1 10712 . G . . . AN=1312;DP=4101 GT:AD:DP:RGQ ./.:0:0:0 chr1 10713 . A . . . AN=1178;DP=4004 GT:AD:DP:RGQ ./.:0:0:0 chr1 10714 . G . . . AN=1324;DP=4102 GT:AD:DP:RGQ ./.:0:0:0 chr1 10715 . A . . . AN=1062;DP=3960 GT:AD:DP:RGQ ./.:0:0:0 chr1 10716 . G . . . AN=1126;DP=4027 GT:AD:DP:RGQ ./.:0:0:0 chr1 10717 . G . . . AN=1312;DP=4081 GT:AD:DP:RGQ ./.:0:0:0 chr1 10718 . C . . . AN=1290;DP=4072 GT:AD:DP:RGQ ./.:0:0:0 chr1 10719 . G C . . AC=0;AF=0;AN=1228;BaseQRankSum=0.135;ClippingRankSum=0.38;DP=4032;ExcessHet=3.01;MQ=1.09;MQRankSum=0.135;ReadPosRankSum=-1 GT:AD:DP:RGQ ./.:0,0:0:0 chr1 10720 . C . . . AN=1228;DP=4048 GT:AD:DP:RGQ ./.:0:0:0 chr1 10721 . G . . . AN=1308;DP=4066 GT:AD:DP:RGQ ./.:0:0:0 chr1 10722 . C . . . AN=1308;DP=4045 GT:AD:DP:RGQ ./.:0:0:0 chr1 10723 . C . . . AN=1302;DP=4034 GT:AD:DP:RGQ ./.:0:0:0 chr1 10724 . G . . . AN=1314;DP=4042 GT:AD:DP:RGQ ./.:0:0:0 chr1 10725 . C . . . AN=1216;DP=4034 GT:AD:DP:RGQ ./.:0:0:0 chr1 10726 . G . . . AN=1302;DP=4056 GT:AD:DP:RGQ ./.:0:0:0 chr1 10727 . C . . . AN=1246;DP=4019 GT:AD:DP:RGQ ./.:0:0:0 chr1 10728 . C . . . AN=1312;DP=4026 GT:AD:DP:RGQ ./.:0:0:0 chr1 10729 . G . . . AN=1304;DP=4021 GT:AD:DP:RGQ ./.:0:0:0 chr1 10730 . G . . . AN=1316;DP=4022 GT:AD:DP:RGQ ./.:0:0:0 chr1 10731 . C . . . AN=1318;DP=4019 GT:AD:DP:RGQ ./.:0:0:0 chr1 10732 . G . . . AN=1316;DP=4016 GT:AD:DP:RGQ ./.:0:0:0 chr1 10733 . C . . . AN=1296;DP=3993 GT:AD:DP:RGQ ./.:0:0:0 chr1 10734 . A . . . AN=1062;DP=3897 GT:AD:DP:RGQ ./.:0:0:0 chr1 10735 . G . . . AN=1306;DP=3995 GT:AD:DP:RGQ ./.:0:0:0 chr1 10736 . G . . . AN=1302;DP=4001 GT:AD:DP:RGQ ./.:0:0:0 chr1 10737 . C . . . AN=1274;DP=3969 GT:AD:DP:RGQ ./.:0:0:0 chr1 10738 . G . . . AN=1310;DP=3983 GT:AD:DP:RGQ ./.:0:0:0 chr1 10739 . C . . . AN=1272;DP=3955 GT:AD:DP:RGQ ./.:0:0:0 chr1 10740 . A . . . AN=1094;DP=3859 GT:AD:DP:RGQ ./.:0:0:0 chr1 10741 . G . . . AN=1292;DP=3936 GT:AD:DP:RGQ ./.:0:0:0 chr1 10742 . A . . . AN=1156;DP=3827 GT:AD:DP:RGQ ./.:0:0:0 chr1 10743 . G . . . AN=1292;DP=3904 GT:AD:DP:RGQ ./.:0:0:0 chr1 10744 . A . . . AN=1086;DP=3788 GT:AD:DP:RGQ ./.:0:0:0 chr1 10745 . G . . . AN=954;DP=3834 GT:AD:DP:RGQ ./.:0:0:0 chr1 10746 . G . . . AN=1260;DP=3879 GT:AD:DP:RGQ ./.:0:0:0 chr1 10747 . C . . . AN=1260;DP=3867 GT:AD:DP:RGQ ./.:0:0:0 chr1 10748 . G . . . AN=1260;DP=3867 GT:AD:DP:RGQ ./.:0:0:0 chr1 10749 . C . . . AN=1192;DP=3873 GT:AD:DP:RGQ ./.:0:0:0 chr1 10750 . G . . . AN=1296;DP=3851 GT:AD:DP:RGQ ./.:0:0:0 chr1 10751 . C . . . AN=1280;DP=3839 GT:AD:DP:RGQ ./.:0:0:0 chr1 10752 . C . . . AN=1266;DP=3848 GT:AD:DP:RGQ ./.:0:0:0 chr1 10753 . G . . . AN=1280;DP=3841 GT:AD:DP:RGQ ./.:0:0:0 chr1 10754 . C . . . AN=1172;DP=3840 GT:AD:DP:RGQ ./.:0:0:0 chr1 10755 . G . . . AN=1290;DP=3860 GT:AD:DP:RGQ ./.:0:0:0 chr1 10756 . C . . . AN=1210;DP=3826 GT:AD:DP:RGQ ./.:0:0:0 chr1 10757 . C . . . AN=1300;DP=3842 GT:AD:DP:RGQ ./.:0:0:0 chr1 10758 . G . . . AN=1306;DP=3853 GT:AD:DP:RGQ ./.:0:0:0 chr1 10759 . G . . . AN=1298;DP=3876 GT:AD:DP:RGQ ./.:0:0:0 chr1 10760 . C . . . AN=1284;DP=3842 GT:AD:DP:RGQ ./.:0:0:0 chr1 10761 . G . . . AN=1302;DP=3849 GT:AD:DP:RGQ ./.:0:0:0 chr1 10762 . C . . . AN=1282;DP=3823 GT:AD:DP:RGQ ./.:0:0:0 chr1 10763 . A . . . AN=1062;DP=3711 GT:AD:DP:RGQ ./.:0:0:0 chr1 10764 . G . . . AN=1274;DP=3837 GT:AD:DP:RGQ ./.:0:0:0 chr1 10765 . G . . . AN=1262;DP=3850 GT:AD:DP:RGQ ./.:0:0:0 chr1 10766 . C . . . AN=1258;DP=3823 GT:AD:DP:RGQ ./.:0:0:0 chr1 10767 . G . . . AN=1278;DP=3840 GT:AD:DP:RGQ ./.:0:0:0 chr1 10768 . C . . . AN=1238;DP=3809 GT:AD:DP:RGQ ./.:0:0:0 chr1 10769 . A . . . AN=1124;DP=3724 GT:AD:DP:RGQ ./.:0:0:0 chr1 10770 . G . . . AN=1274;DP=3832 GT:AD:DP:RGQ ./.:0:0:0 chr1 10771 . A . . . AN=1120;DP=3695 GT:AD:DP:RGQ ./.:0:0:0 chr1 10772 . G . . . AN=1218;DP=3828 GT:AD:DP:RGQ ./.:0:0:0 chr1 10773 . A . . . AN=1054;DP=3638 GT:AD:DP:RGQ ./.:0:0:0 chr1 10774 . G . . . AN=848;DP=3706 GT:AD:DP:RGQ ./.:0:0:0 chr1 10775 . G . . . AN=1158;DP=3722 GT:AD:DP:RGQ ./.:0:0:0 chr1 10776 . C . . . AN=1146;DP=3667 GT:AD:DP:RGQ ./.:0:0:0 chr1 10777 . G . . . AN=1158;DP=3617 GT:AD:DP:RGQ ./.:0:0:0 chr1 10778 . C . . . AN=1132;DP=3562 GT:AD:DP:RGQ ./.:0:0:0 chr1 10779 . G . . . AN=1144;DP=3458 GT:AD:DP:RGQ ./.:0:0:0 chr1 10780 . C . . . AN=1102;DP=3365 GT:AD:DP:RGQ ./.:0:0:0 chr1 10781 . C . . . AN=1066;DP=3315 GT:AD:DP:RGQ ./.:0:0:0 chr1 10782 . G . . . AN=1042;DP=3219 GT:AD:DP:RGQ ./.:0:0:0 chr1 10783 . C G . . AC=0;AF=0;AN=934;BaseQRankSum=0.804;ClippingRankSum=0.804;DP=3129;ExcessHet=3.01;MQ=0.51;MQRankSum=0.804;ReadPosRankSum=0.804 GT:AD:DP:RGQ ./.:0,0:0:0 chr1 10784 . G . . . AN=968;DP=3028 GT:AD:DP:RGQ ./.:0:0:0 chr1 10785 . C . . . AN=940;DP=2915 GT:AD:DP:RGQ ./.:0:0:0 chr1 10786 . C . . . AN=950;DP=2893 GT:AD:DP:RGQ ./.:0:0:0 chr1 10787 . G . . . AN=928;DP=2800 GT:AD:DP:RGQ ./.:0:0:0 chr1 10788 . G . . . AN=908;DP=2737 GT:AD:DP:RGQ ./.:0:0:0 chr1 10789 . C . . . AN=922;DP=2671 GT:AD:DP:RGQ ./.:0:0:0 chr1 10790 . G . . . AN=928;DP=2578 GT:AD:DP:RGQ ./.:0:0:0 chr1 10791 . C . . . AN=890;DP=2487 GT:AD:DP:RGQ ./.:0:0:0 chr1 10792 . A . . . AN=708;DP=2336 GT:AD:DP:RGQ ./.:0:0:0 chr1 10793 . G . . . AN=890;DP=2386 GT:AD:DP:RGQ ./.:0:0:0 chr1 10794 . G . . . AN=870;DP=2339 GT:AD:DP:RGQ ./.:0:0:0 chr1 10795 . C . . . AN=826;DP=2213 GT:AD:DP:RGQ ./.:0:0:0 chr1 10796 . G . . . AN=820;DP=2141 GT:AD:DP:RGQ ./.:0:0:0 chr1 10797 . C . . . AN=794;DP=2045 GT:AD:DP:RGQ ./.:0:0:0 chr1 10798 . A . . . AN=686;DP=1923 GT:AD:DP:RGQ ./.:0:0:0 chr1 10799 . G . . . AN=784;DP=1955 GT:AD:DP:RGQ ./.:0:0:0 chr1 10800 . A . . . AN=660;DP=1868 GT:AD:DP:RGQ ./.:0:0:0 chr1 10801 . C . . . AN=656;DP=1826 GT:AD:DP:RGQ ./.:0:0:0 chr1 10802 . A . . . AN=654;DP=1824 GT:AD:DP:RGQ ./.:0:0:0 chr1 10803 . C . . . AN=642;DP=1807 GT:AD:DP:RGQ ./.:0:0:0 chr1 10804 . A . . . AN=524;DP=1760 GT:AD:DP:RGQ ./.:0:0:0 chr1 10805 . T . . . AN=412;DP=1747 GT:AD:DP:RGQ ./.:0:0:0 chr1 10806 . G . . . AN=470;DP=1767 GT:AD:DP:RGQ ./.:0:0:0 chr1 10807 . C . . . AN=438;DP=1746 GT:AD:DP:RGQ ./.:0:0:0 chr1 10808 . T . . . AN=338;DP=1719 GT:AD:DP:RGQ ./.:0:0:0 chr1 10809 . A . . . AN=246;DP=1729 GT:AD:DP:RGQ ./.:0:0:0 chr1 10810 . G . . . AN=282;DP=1746 GT:AD:DP:RGQ ./.:0:0:0 chr1 10811 . C . . . AN=280;DP=1735 GT:AD:DP:RGQ ./.:0:0:0 chr1 10812 . G . . . AN=280;DP=1740 GT:AD:DP:RGQ ./.:0:0:0 chr1 10813 . C . . . AN=246;DP=1727 GT:AD:DP:RGQ ./.:0:0:0 chr1 10814 . G . . . AN=270;DP=1713 GT:AD:DP:RGQ ./.:0:0:0 chr1 10815 . T . . . AN=120;DP=1669 GT:AD:DP:RGQ ./.:0:0:0 chr1 10816 . C CCA 334.85 . AC=7;AF=0.022;AN=324;BaseQRankSum=0.736;ClippingRankSum=-0.736;DP=1688;ExcessHet=0.001;FS=0;InbreedingCoeff=-0.0721;MLEAC=10;MLEAF=0.031;MQ=1.71;MQRankSum=-0.736;QD=30.44;ReadPosRankSum=-0.736;SOR=0.399 GT:AD:DP:GQ:PL ./.:0,0:0:.:. chr1 10817 . G . . . AN=532;DP=1696 GT:AD:DP:RGQ ./.:0:0:0 chr1 10818 . G . . . AN=930;DP=1687 GT:AD:DP:RGQ ./.:0:0:0 chr1 10819 . G T . . AC=0;AF=0;AN=970;BaseQRankSum=-0.736;ClippingRankSum=0.736;DP=1672;ExcessHet=3.01;MQ=1.09;MQRankSum=0.736;ReadPosRankSum=-0.736 GT:AD:DP:RGQ ./.:0,0:0:0 chr1 10820 . G . . . AN=986;DP=1652 GT:AD:DP:RGQ ./.:0:0:0 chr1 10821 . T . . . AN=576;DP=1580 GT:AD:DP:RGQ ./.:0:0:0 chr1 10822 . G . . . AN=974;DP=1612 GT:AD:DP:RGQ ./.:0:0:0 chr1 10823 . G . . . AN=944;DP=1601 GT:AD:DP:RGQ ./.:0:0:0 chr1 10824 . A . . . AN=658;DP=1561 GT:AD:DP:RGQ ./.:0:0:0 chr1 10825 . G . . . AN=966;DP=1562 GT:AD:DP:RGQ ./.:0:0:0 chr1 10826 . G . . . AN=922;DP=1553 GT:AD:DP:RGQ ./.:0:0:0 chr1 10827 . C . . . AN=904;DP=1521 GT:AD:DP:RGQ ./.:0:0:0 chr1 10828 . G . . . AN=940;DP=1519 GT:AD:DP:RGQ ./.:0:0:0 chr1 10829 . T . . . AN=608;DP=1487 GT:AD:DP:RGQ ./.:0:0:0 chr1 10830 . G . . . AN=950;DP=1517 GT:AD:DP:RGQ ./.:0:0:0 chr1 10831 . G . . . AN=948;DP=1506 GT:AD:DP:RGQ ./.:0:0:0 chr1 10832 . C . . . AN=932;DP=1473 GT:AD:DP:RGQ ./.:0:0:0 chr1 10833 . G . . . AN=962;DP=1467 GT:AD:DP:RGQ ./.:0:0:0 chr1 10834 . C . . . AN=930;DP=1456 GT:AD:DP:RGQ ./.:0:0:0 chr1 10835 . A . . . AN=708;DP=1432 GT:AD:DP:RGQ ./.:0:0:0 chr1 10836 . G . . . AN=908;DP=1441 GT:AD:DP:RGQ ./.:0:0:0 chr1 10837 . G . . . AN=898;DP=1442 GT:AD:DP:RGQ ./.:0:0:0 chr1 10838 . C . . . AN=872;DP=1427 GT:AD:DP:RGQ ./.:0:0:0 chr1 10839 . G . . . AN=920;DP=1430 GT:AD:DP:RGQ ./.:0:0:0 chr1 10840 . C . . . AN=884;DP=1404 GT:AD:DP:RGQ ./.:0:0:0 chr1 10841 . A . . . AN=772;DP=1375 GT:AD:DP:RGQ ./.:0:0:0 chr1 10842 . G . . . AN=908;DP=1387 GT:AD:DP:RGQ ./.:0:0:0 chr1 10843 . A . . . AN=756;DP=1363 GT:AD:DP:RGQ ./.:0:0:0 chr1 10844 . G . . . AN=892;DP=1365 GT:AD:DP:RGQ ./.:0:0:0 chr1 10845 . A . . . AN=692;DP=1347 GT:AD:DP:RGQ ./.:0:0:0 chr1 10846 . G . . . AN=888;DP=1342 GT:AD:DP:RGQ ./.:0:0:0 chr1 10847 . G . . . AN=898;DP=1326 GT:AD:DP:RGQ ./.:0:0:0 chr1 10848 . C . . . AN=848;DP=1301 GT:AD:DP:RGQ ./.:0:0:0 chr1 10849 . G . . . AN=894;DP=1282 GT:AD:DP:RGQ ./.:0:0:0 chr1 10850 . C . . . AN=894;DP=1261 GT:AD:DP:RGQ ./.:0:0:0 chr1 10851 . G . . . AN=898;DP=1242 GT:AD:DP:RGQ ./.:0:0:0 chr1 10852 . C . . . AN=888;DP=1209 GT:AD:DP:RGQ ./.:0:0:0 chr1 10853 . C . . . AN=868;DP=1194 GT:AD:DP:RGQ ./.:0:0:0 chr1 10854 . G . . . AN=922;DP=1180 GT:AD:DP:RGQ ./.:0:0:0 chr1 10855 . C . . . AN=894;DP=1188 GT:AD:DP:RGQ ./.:0:0:0 chr1 10856 . G . . . AN=904;DP=1192 GT:AD:DP:RGQ ./.:0:0:0 chr1 10857 . C . . . AN=836;DP=1192 GT:AD:DP:RGQ ./.:0:0:0 chr1 10858 . C . . . AN=886;DP=1198 GT:AD:DP:RGQ ./.:0:0:0 chr1 10859 . G . . . AN=908;DP=1202 GT:AD:DP:RGQ ./.:0:0:0 chr1 10860 . G . . . AN=914;DP=1220 GT:AD:DP:RGQ ./.:0:0:0 chr1 10861 . C . . . AN=906;DP=1228 GT:AD:DP:RGQ ./.:0:0:0 chr1 10862 . G . . . AN=940;DP=1242 GT:AD:DP:RGQ ./.:0:0:0 chr1 10863 . C . . . AN=902;DP=1245 GT:AD:DP:RGQ ./.:0:0:0 chr1 10864 . A . . . AN=734;DP=1234 GT:AD:DP:RGQ ./.:0:0:0 chr1 10865 . G . . . AN=932;DP=1254 GT:AD:DP:RGQ ./.:0:0:0 chr1 10866 . G . . . AN=922;DP=1254 GT:AD:DP:RGQ ./.:0:0:0 chr1 10867 . C . . . AN=846;DP=1251 GT:AD:DP:RGQ ./.:0:0:0 chr1 10868 . G . . . AN=936;DP=1262 GT:AD:DP:RGQ ./.:0:0:0 chr1 10869 . C . . . AN=842;DP=1264 GT:AD:DP:RGQ ./.:0:0:0 chr1 10870 . A . . . AN=748;DP=1264 GT:AD:DP:RGQ ./.:0:0:0 chr1 10871 . G . . . AN=942;DP=1277 GT:AD:DP:RGQ ./.:0:0:0 chr1 10872 . A . . . AN=752;DP=1280 GT:AD:DP:RGQ ./.:0:0:0 chr1 10873 . G . . . AN=926;DP=1295 GT:AD:DP:RGQ ./.:0:0:0 chr1 10874 . A . . . AN=724;DP=1296 GT:AD:DP:RGQ ./.:0:0:0 chr1 10875 . C . . . AN=944;DP=1299 GT:AD:DP:RGQ ./.:0:0:0 chr1 10876 . A . . . AN=724;DP=1299 GT:AD:DP:RGQ ./.:0:0:0 chr1 10877 . C . . . AN=902;DP=1295 GT:AD:DP:RGQ ./.:0:0:0 chr1 10878 . A . . . AN=718;DP=1296 GT:AD:DP:RGQ ./.:0:0:0 chr1 10879 . T . . . AN=704;DP=1296 GT:AD:DP:RGQ ./.:0:0:0 chr1 10880 . G . . . AN=974;DP=1311 GT:AD:DP:RGQ ./.:0:0:0 chr1 10881 . C . . . AN=944;DP=1303 GT:AD:DP:RGQ ./.:0:0:0 chr1 10882 . T . . . AN=662;DP=1303 GT:AD:DP:RGQ ./.:0:0:0 chr1 10883 . A . . . AN=590;DP=1298 GT:AD:DP:RGQ ./.:0:0:0 chr1 10884 . C . . . AN=880;DP=1307 GT:AD:DP:RGQ ./.:0:0:0 chr1 10885 . C . . . AN=906;DP=1317 GT:AD:DP:RGQ ./.:0:0:0 chr1 10886 . G . . . AN=956;DP=1321 GT:AD:DP:RGQ ./.:0:0:0 chr1 10887 . C . . . AN=958;DP=1311 GT:AD:DP:RGQ ./.:0:0:0 chr1 10888 . G . . . AN=948;DP=1314 GT:AD:DP:RGQ ./.:0:0:0 chr1 10889 . T . . . AN=534;DP=1305 GT:AD:DP:RGQ ./.:0:0:0 chr1 10890 . C . . . AN=962;DP=1319 GT:AD:DP:RGQ ./.:0:0:0 chr1 10891 . C . . . AN=876;DP=1325 GT:AD:DP:RGQ ./.:0:0:0 chr1 10892 . A . . . AN=826;DP=1329 GT:AD:DP:RGQ ./.:0:0:0 chr1 10893 . G . . . AN=988;DP=1335 GT:AD:DP:RGQ ./.:0:0:0 chr1 10894 . G . . . AN=998;DP=1338 GT:AD:DP:RGQ ./.:0:0:0 chr1 10895 . G . . . AN=966;DP=1341 GT:AD:DP:RGQ ./.:0:0:0 chr1 10896 . G . . . AN=992;DP=1348 GT:AD:DP:RGQ ./.:0:0:0 chr1 10897 . T . . . AN=678;DP=1342 GT:AD:DP:RGQ ./.:0:0:0 chr1 10898 . G . . . AN=1012;DP=1378 GT:AD:DP:RGQ ./.:0:0:0 chr1 10899 . G . . . AN=964;DP=1374 GT:AD:DP:RGQ ./.:0:0:0 chr1 10900 . A . . . AN=680;DP=1375 GT:AD:DP:RGQ ./.:0:0:0 chr1 10901 . G . . . AN=1016;DP=1403 GT:AD:DP:RGQ ./.:0:0:0 chr1 10902 . G . . . AN=944;DP=1414 GT:AD:DP:RGQ ./.:0:0:0 chr1 10903 . C . . . AN=920;DP=1409 GT:AD:DP:RGQ ./.:0:0:0 chr1 10904 . G A 265.79 . AC=3;AF=0.003464;AN=866;BaseQRankSum=0.762;ClippingRankSum=-0.762;DP=1424;ExcessHet=0.113;FS=0;InbreedingCoeff=-0.1149;MLEAC=3;MLEAF=0.003464;MQ=1.88;MQRankSum=0.067;QD=22.15;ReadPosRankSum=1.18;SOR=2.67 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 10905 . T . . . AN=582;DP=1425 GT:AD:DP:RGQ ./.:0:0:0 chr1 10906 . G . . . AN=1008;DP=1456 GT:AD:DP:RGQ ./.:0:0:0 chr1 10907 . G . . . AN=1004;DP=1464 GT:AD:DP:RGQ ./.:0:0:0 chr1 10908 . C . . . AN=1008;DP=1454 GT:AD:DP:RGQ ./.:0:0:0 chr1 10909 . G . . . AN=1036;DP=1470 GT:AD:DP:RGQ ./.:0:0:0 chr1 10910 . C . . . AN=1002;DP=1472 GT:AD:DP:RGQ ./.:0:0:0 chr1 10911 . A . . . AN=794;DP=1478 GT:AD:DP:RGQ ./.:0:0:0 chr1 10912 . G . . . AN=1020;DP=1498 GT:AD:DP:RGQ ./.:0:0:0 chr1 10913 . G . . . AN=1018;DP=1502 GT:AD:DP:RGQ ./.:0:0:0 chr1 10914 . C . . . AN=956;DP=1503 GT:AD:DP:RGQ ./.:0:0:0 chr1 10915 . G . . . AN=1056;DP=1513 GT:AD:DP:RGQ ./.:0:0:0 chr1 10916 . C . . . AN=1008;DP=1515 GT:AD:DP:RGQ ./.:0:0:0 chr1 10917 . A . . . AN=838;DP=1525 GT:AD:DP:RGQ ./.:0:0:0 chr1 10918 . G . . . AN=1054;DP=1553 GT:AD:DP:RGQ ./.:0:0:0 chr1 10919 . A . . . AN=882;DP=1550 GT:AD:DP:RGQ ./.:0:0:0 chr1 10920 . G . . . AN=1060;DP=1563 GT:AD:DP:RGQ ./.:0:0:0 chr1 10921 . A . . . AN=774;DP=1559 GT:AD:DP:RGQ ./.:0:0:0 chr1 10922 . G . . . AN=1036;DP=1565 GT:AD:DP:RGQ ./.:0:0:0 chr1 10923 . G . . . AN=1038;DP=1564 GT:AD:DP:RGQ ./.:0:0:0 chr1 10924 . C . . . AN=960;DP=1555 GT:AD:DP:RGQ ./.:0:0:0 chr1 10925 . G . . . AN=1046;DP=1544 GT:AD:DP:RGQ ./.:0:0:0 chr1 10926 . C . . . AN=1022;DP=1536 GT:AD:DP:RGQ ./.:0:0:0 chr1 10927 . A G 344.47 . AC=2;AF=0.004717;AN=424;BaseQRankSum=2.02;ClippingRankSum=0.742;DP=1523;ExcessHet=3.0697;FS=0;InbreedingCoeff=-0.1703;MLEAC=6;MLEAF=0.014;MQ=2.05;MQRankSum=0.922;QD=22.96;ReadPosRankSum=0.742;SOR=1.473 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 10928 . C . . . AN=1012;DP=1531 GT:AD:DP:RGQ ./.:0:0:0 chr1 10929 . C . . . AN=954;DP=1525 GT:AD:DP:RGQ ./.:0:0:0 chr1 10930 . G . . . AN=1018;DP=1522 GT:AD:DP:RGQ ./.:0:0:0 chr1 10931 . C . . . AN=1006;DP=1511 GT:AD:DP:RGQ ./.:0:0:0 chr1 10932 . G . . . AN=1014;DP=1499 GT:AD:DP:RGQ ./.:0:0:0 chr1 10933 . C . . . AN=1000;DP=1494 GT:AD:DP:RGQ ./.:0:0:0 chr1 10934 . C . . . AN=922;DP=1490 GT:AD:DP:RGQ ./.:0:0:0 chr1 10935 . G . . . AN=1010;DP=1477 GT:AD:DP:RGQ ./.:0:0:0 chr1 10936 . G . . . AN=1020;DP=1463 GT:AD:DP:RGQ ./.:0:0:0 chr1 10937 . C . . . AN=986;DP=1450 GT:AD:DP:RGQ ./.:0:0:0 chr1 10938 . G A 111.03 . AC=1;AF=0.0009804;AN=1020;BaseQRankSum=0;ClippingRankSum=0.421;DP=1433;ExcessHet=3.0103;FS=0;InbreedingCoeff=-0.103;MLEAC=1;MLEAF=0.0009804;MQ=1.58;MQRankSum=-1.368;QD=13.88;ReadPosRankSum=-0.421;SOR=0.693 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 10939 . C . . . AN=1006;DP=1429 GT:AD:DP:RGQ ./.:0:0:0 chr1 10940 . A . . . AN=794;DP=1414 GT:AD:DP:RGQ ./.:0:0:0 chr1 10941 . G . . . AN=1022;DP=1411 GT:AD:DP:RGQ ./.:0:0:0 chr1 10942 . G . . . AN=1002;DP=1405 GT:AD:DP:RGQ ./.:0:0:0 chr1 10943 . C . . . AN=916;DP=1387 GT:AD:DP:RGQ ./.:0:0:0 chr1 10944 . G . . . AN=1030;DP=1380 GT:AD:DP:RGQ ./.:0:0:0 chr1 10945 . C . . . AN=974;DP=1371 GT:AD:DP:RGQ ./.:0:0:0 chr1 10946 . A . . . AN=908;DP=1369 GT:AD:DP:RGQ ./.:0:0:0 chr1 10947 . G . . . AN=1012;DP=1361 GT:AD:DP:RGQ ./.:0:0:0 chr1 10948 . A . . . AN=932;DP=1358 GT:AD:DP:RGQ ./.:0:0:0 chr1 10949 . G C . . AC=0;AF=0;AN=1004;BaseQRankSum=0.406;ClippingRankSum=0.406;DP=1353;ExcessHet=3.01;MQ=1.33;MQRankSum=-0.988;ReadPosRankSum=0.406 GT:AD:DP:RGQ ./.:0,0:0:0 chr1 10950 . A . . . AN=908;DP=1347 GT:AD:DP:RGQ ./.:0:0:0 chr1 10951 . C . . . AN=1006;DP=1339 GT:AD:DP:RGQ ./.:0:0:0 chr1 10952 . A . . . AN=918;DP=1331 GT:AD:DP:RGQ ./.:0:0:0 chr1 10953 . C . . . AN=998;DP=1323 GT:AD:DP:RGQ ./.:0:0:0 chr1 10954 . A . . . AN=910;DP=1321 GT:AD:DP:RGQ ./.:0:0:0 chr1 10955 . T . . . AN=866;DP=1318 GT:AD:DP:RGQ ./.:0:0:0 chr1 10956 . G . . . AN=984;DP=1311 GT:AD:DP:RGQ ./.:0:0:0 chr1 10957 . C . . . AN=988;DP=1304 GT:AD:DP:RGQ ./.:0:0:0 chr1 10958 . T . . . AN=896;DP=1299 GT:AD:DP:RGQ ./.:0:0:0 chr1 10959 . A . . . AN=842;DP=1292 GT:AD:DP:RGQ ./.:0:0:0 chr1 10960 . G . . . AN=950;DP=1278 GT:AD:DP:RGQ ./.:0:0:0 chr1 10961 . C . . . AN=984;DP=1266 GT:AD:DP:RGQ ./.:0:0:0 chr1 10962 . G . . . AN=976;DP=1248 GT:AD:DP:RGQ ./.:0:0:0 chr1 10963 . C . . . AN=976;DP=1237 GT:AD:DP:RGQ ./.:0:0:0 chr1 10964 . G . . . AN=962;DP=1226 GT:AD:DP:RGQ ./.:0:0:0 chr1 10965 . T . . . AN=732;DP=1221 GT:AD:DP:RGQ ./.:0:0:0 chr1 10966 . C . . . AN=970;DP=1217 GT:AD:DP:RGQ ./.:0:0:0 chr1 10967 . C . . . AN=936;DP=1208 GT:AD:DP:RGQ ./.:0:0:0 chr1 10968 . A . . . AN=838;DP=1206 GT:AD:DP:RGQ ./.:0:0:0 chr1 10969 . G . . . AN=962;DP=1199 GT:AD:DP:RGQ ./.:0:0:0 chr1 10970 . G . . . AN=958;DP=1191 GT:AD:DP:RGQ ./.:0:0:0 chr1 10971 . G . . . AN=946;DP=1187 GT:AD:DP:RGQ ./.:0:0:0 chr1 10972 . G . . . AN=936;DP=1180 GT:AD:DP:RGQ ./.:0:0:0 chr1 10973 . T . . . AN=800;DP=1165 GT:AD:DP:RGQ ./.:0:0:0 chr1 10974 . G . . . AN=946;DP=1160 GT:AD:DP:RGQ ./.:0:0:0 chr1 10975 . G . . . AN=924;DP=1152 GT:AD:DP:RGQ ./.:0:0:0 chr1 10976 . A . . . AN=820;DP=1143 GT:AD:DP:RGQ ./.:0:0:0 chr1 10977 . G . . . AN=944;DP=1132 GT:AD:DP:RGQ ./.:0:0:0 chr1 10978 . G T . . AC=0;AF=0;AN=928;BaseQRankSum=1.03;ClippingRankSum=1.03;DP=1114;ExcessHet=3.01;MQ=1.2;MQRankSum=0;ReadPosRankSum=0 GT:AD:DP:RGQ ./.:0,0:0:0 chr1 10979 . C . . . AN=892;DP=1108 GT:AD:DP:RGQ ./.:0:0:0 chr1 10980 . G . . . AN=920;DP=1086 GT:AD:DP:RGQ ./.:0:0:0 chr1 10981 . T . . . AN=676;DP=1078 GT:AD:DP:RGQ ./.:0:0:0 chr1 10982 . G . . . AN=914;DP=1072 GT:AD:DP:RGQ ./.:0:0:0 chr1 10983 . G . . . AN=916;DP=1069 GT:AD:DP:RGQ ./.:0:0:0 chr1 10984 . C . . . AN=916;DP=1063 GT:AD:DP:RGQ ./.:0:0:0 chr1 10985 . G . . . AN=918;DP=1047 GT:AD:DP:RGQ ./.:0:0:0 chr1 10986 . C . . . AN=904;DP=1040 GT:AD:DP:RGQ ./.:0:0:0 chr1 10987 . A . . . AN=858;DP=1038 GT:AD:DP:RGQ ./.:0:0:0 chr1 10988 . G . . . AN=902;DP=1028 GT:AD:DP:RGQ ./.:0:0:0 chr1 10989 . G . . . AN=892;DP=1018 GT:AD:DP:RGQ ./.:0:0:0 chr1 10990 . C G 44.76 . AC=5;AF=0.006143;AN=814;BaseQRankSum=1.03;ClippingRankSum=0;DP=999;ExcessHet=0.0014;FS=0;InbreedingCoeff=-0.1212;MLEAC=4;MLEAF=0.004914;MQ=1.9;MQRankSum=-1.026;QD=6.39;ReadPosRankSum=1.03;SOR=1.402 GT:AD:DP:GQ:PL ./.:0,0:0:.:. chr1 10991 . G . . . AN=890;DP=992 GT:AD:DP:RGQ ./.:0:0:0 chr1 10992 . C . . . AN=886;DP=985 GT:AD:DP:RGQ ./.:0:0:0 chr1 10993 . A . . . AN=864;DP=978 GT:AD:DP:RGQ ./.:0:0:0 chr1 10994 . G C . . AC=0;AF=0;AN=890;DP=969;ExcessHet=3.01;MQ=0.95 GT:AD:DP:PGT:PID:RGQ ./.:0,0:0:.:.:0 chr1 10995 . A . . . AN=846;DP=966 GT:AD:DP:RGQ ./.:0:0:0 chr1 10996 . G . . . AN=882;DP=961 GT:AD:DP:RGQ ./.:0:0:0 chr1 10997 . A . . . AN=812;DP=956 GT:AD:DP:RGQ ./.:0:0:0 chr1 10998 . C . . . AN=836;DP=948 GT:AD:DP:RGQ ./.:0:0:0 chr1 10999 . G . . . AN=854;DP=941 GT:AD:DP:RGQ ./.:0:0:0 chr1 11000 . C . . . AN=838;DP=938 GT:AD:DP:RGQ ./.:0:0:0 chr1 11001 . A . . . AN=830;DP=932 GT:AD:DP:RGQ ./.:0:0:0 chr1 11002 . A . . . AN=796;DP=926 GT:AD:DP:RGQ ./.:0:0:0 chr1 11003 . G . . . AN=800;DP=923 GT:AD:DP:RGQ ./.:0:0:0 chr1 11004 . C . . . AN=804;DP=915 GT:AD:DP:RGQ ./.:0:0:0 chr1 11005 . C . . . AN=794;DP=909 GT:AD:DP:RGQ ./.:0:0:0 chr1 11006 . T . . . AN=772;DP=903 GT:AD:DP:RGQ ./.:0:0:0 chr1 11007 . A . . . AN=768;DP=891 GT:AD:DP:RGQ ./.:0:0:0 chr1 11008 . C . . . AN=780;DP=876 GT:AD:DP:RGQ ./.:0:0:0 chr1 11009 . G . . . AN=792;DP=862 GT:AD:DP:RGQ ./.:0:0:0 chr1 11010 . G . . . AN=776;DP=855 GT:AD:DP:RGQ ./.:0:0:0 chr1 11011 . G C . . AC=0;AF=0;AN=774;DP=835;ExcessHet=3.01;MQ=0.73 GT:AD:DP:PGT:PID:RGQ ./.:0,0:0:.:.:0 chr1 11012 . C . . . AN=748;DP=816 GT:AD:DP:RGQ ./.:0:0:0 chr1 11013 . G . . . AN=736;DP=798 GT:AD:DP:RGQ ./.:0:0:0 chr1 11014 . G A 71.59 . AC=1;AF=0.001397;AN=716;BaseQRankSum=0;ClippingRankSum=0;DP=787;ExcessHet=3.0468;FS=0;InbreedingCoeff=-0.1474;MLEAC=1;MLEAF=0.001397;MQ=1.89;MQRankSum=0.55;QD=10.23;ReadPosRankSum=0.55;SOR=0.495 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 11015 . G . . . AN=738;DP=787 GT:AD:DP:RGQ ./.:0:0:0 chr1 11016 . G . . . AN=742;DP=775 GT:AD:DP:RGQ ./.:0:0:0 chr1 11017 . G . . . AN=738;DP=765 GT:AD:DP:RGQ ./.:0:0:0 chr1 11018 . T . . . AN=720;DP=758 GT:AD:DP:RGQ ./.:0:0:0 chr1 11019 . T . . . AN=664;DP=744 GT:AD:DP:RGQ ./.:0:0:0 chr1 11020 . G . . . AN=722;DP=741 GT:AD:DP:RGQ ./.:0:0:0 chr1 11021 . G . . . AN=718;DP=731 GT:AD:DP:RGQ ./.:0:0:0 chr1 11022 . G A 99.81 . AC=3;AF=0.004505;AN=666;BaseQRankSum=0.988;ClippingRankSum=0.406;DP=719;ExcessHet=0.0198;FS=0;InbreedingCoeff=-0.1279;MLEAC=3;MLEAF=0.004505;MQ=2.14;MQRankSum=0.406;QD=12.48;ReadPosRankSum=0.406;SOR=1.179 GT:AD:DP:GQ:PGT:PID:PL ./.:0,0:0:.:.:.:. chr1 11023 . G . . . AN=706;DP=708 GT:AD:DP:RGQ ./.:0:0:0 chr1 11024 . G . . . AN=702;DP=699 GT:AD:DP:RGQ ./.:0:0:0 chr1 11025 . G . . . AN=706;DP=689 GT:AD:DP:RGQ ./.:0:0:0 chr1 11026 . G . . . AN=690;DP=679 GT:AD:DP:RGQ ./.:0:0:0 chr1 11027 . C . . . AN=672;DP=672 GT:AD:DP:RGQ ./.:0:0:0 chr1 11028 . G . . . AN=690;DP=668 GT:AD:DP:RGQ ./.:0:0:0 chr1 11029 . T . . . AN=656;DP=659 GT:AD:DP:RGQ ./.:0:0:0 chr1 11030 . G . . . AN=678;DP=651 GT:AD:DP:RGQ ./.:0:0:0 chr1 11031 . T . . . AN=652;DP=646 GT:AD:DP:RGQ ./.:0:0:0 chr1 11032 . G . . . AN=674;DP=640 GT:AD:DP:RGQ ./.:0:0:0 chr1 11033 . T . . . AN=632;DP=630 GT:AD:DP:RGQ ./.:0:0:0 chr1 11034 . T . . . AN=614;DP=625 GT:AD:DP:RGQ ./.:0:0:0 chr1 11035 . G . . . AN=646;DP=621 GT:AD:DP:RGQ ./.:0:0:0 chr1 11036 . C . . . AN=612;DP=612 GT:AD:DP:RGQ ./.:0:0:0 chr1 11037 . A . . . AN=582;DP=601 GT:AD:DP:RGQ ./.:0:0:0 chr1 11038 . G . . . AN=610;DP=597 GT:AD:DP:RGQ ./.:0:0:0 chr1 11039 . G . . . AN=576;DP=593 GT:AD:DP:RGQ ./.:0:0:0 chr1 11040 . A . . . AN=538;DP=580 GT:AD:DP:RGQ ./.:0:0:0 chr1 11041 . G . . . AN=534;DP=580 GT:AD:DP:RGQ ./.:0:0:0 chr1 11042 . C . . . AN=496;DP=570 GT:AD:DP:RGQ ./.:0:0:0 chr1 11043 . A . . . AN=494;DP=561 GT:AD:DP:RGQ ./.:0:0:0 chr1 11044 . A . . . AN=466;DP=558 GT:AD:DP:RGQ ./.:0:0:0 chr1 11045 . A . . . AN=412;DP=551 GT:AD:DP:RGQ ./.:0:0:0 chr1 11046 . G . . . AN=418;DP=536 GT:AD:DP:RGQ ./.:0:0:0 chr1 11047 . T . . . AN=362;DP=520 GT:AD:DP:RGQ ./.:0:0:0 chr1 11048 . C . . . AN=348;DP=501 GT:AD:DP:RGQ ./.:0:0:0 chr1 11049 . G . . . AN=360;DP=472 GT:AD:DP:RGQ ./.:0:0:0 chr1 11050 . C . . . AN=340;DP=464 GT:AD:DP:RGQ ./.:0:0:0 chr1 11051 . A . . . AN=288;DP=452 GT:AD:DP:RGQ ./.:0:0:0 chr1 11052 . C . . . AN=276;DP=435 GT:AD:DP:RGQ ./.:0:0:0 chr1 11053 . G . . . AN=340;DP=416 GT:AD:DP:RGQ ./.:0:0:0 chr1 11054 . G . . . AN=300;DP=398 GT:AD:DP:RGQ ./.:0:0:0 chr1 11055 . C . . . AN=266;DP=381 GT:AD:DP:RGQ ./.:0:0:0 chr1 11056 . G . . . AN=262;DP=359 GT:AD:DP:RGQ ./.:0:0:0 chr1 11057 . C . . . AN=214;DP=341 GT:AD:DP:RGQ ./.:0:0:0 chr1 11058 . C . . . AN=72;DP=330 GT:AD:DP:RGQ ./.:0:0:0 chr1 11059 . G . . . AN=182;DP=321 GT:AD:DP:RGQ ./.:0:0:0 chr1 11060 . G . . . AN=198;DP=311 GT:AD:DP:RGQ ./.:0:0:0 chr1 11061 . G . . . AN=202;DP=296 GT:AD:DP:RGQ ./.:0:0:0 chr1 11062 . C . . . AN=86;DP=284 GT:AD:DP:RGQ ./.:0:0:0 chr1 11063 . T . . . AN=32;DP=282 GT:AD:DP:RGQ ./.:0:0:0 chr1 11064 . G . . . AN=216;DP=279 GT:AD:DP:RGQ ./.:0:0:0 chr1 11065 . G . . . AN=212;DP=270 GT:AD:DP:RGQ ./.:0:0:0 chr1 11066 . G . . . AN=230;DP=267 GT:AD:DP:RGQ ./.:0:0:0 chr1 11067 . G . . . AN=240;DP=253 GT:AD:DP:RGQ ./.:0:0:0 chr1 11068 . C . . . AN=74;DP=242 GT:AD:DP:RGQ ./.:0:0:0 chr1 11069 . G . . . AN=254;DP=224 GT:AD:DP:RGQ ./.:0:0:0 chr1 11070 . G . . . AN=264;DP=217 GT:AD:DP:RGQ ./.:0:0:0 chr1 11071 . G . . . AN=256;DP=212 GT:AD:DP:RGQ ./.:0:0:0 chr1 11072 . G . . . AN=270;DP=202 GT:AD:DP:RGQ ./.:0:0:0 chr1 11073 . G . . . AN=266;DP=197 GT:AD:DP:RGQ ./.:0:0:0 chr1 11074 . G . . . AN=266;DP=195 GT:AD:DP:RGQ ./.:0:0:0 chr1 11075 . A . . . AN=38;DP=193 GT:AD:DP:RGQ ./.:0:0:0 chr1 11076 . G . . . AN=286;DP=197 GT:AD:DP:RGQ ./.:0:0:0 chr1 11077 . G . . . AN=306;DP=200 GT:AD:DP:RGQ ./.:0:0:0 chr1 11078 . G . . . AN=302;DP=197 GT:AD:DP:RGQ ./.:0:0:0 chr1 11079 . T . . . AN=132;DP=193 GT:AD:DP:RGQ ./.:0:0:0 chr1 11080 . G . . . AN=300;DP=201 GT:AD:DP:RGQ ./.:0:0:0 chr1 11081 . G . . . AN=254;DP=203 GT:AD:DP:RGQ ./.:0:0:0 chr1 11082 . C . . . AN=300;DP=204 GT:AD:DP:RGQ ./.:0:0:0 chr1 11083 . G . . . AN=318;DP=208 GT:AD:DP:RGQ ./.:0:0:0 chr1 11084 . C . . . AN=332;DP=213 GT:AD:DP:RGQ ./.:0:0:0 chr1 11085 . C . . . AN=316;DP=217 GT:AD:DP:RGQ ./.:0:0:0 chr1 11086 . G . . . AN=330;DP=222 GT:AD:DP:RGQ ./.:0:0:0 chr1 11087 . T . . . AN=260;DP=225 GT:AD:DP:RGQ ./.:0:0:0 chr1 11088 . G . . . AN=350;DP=231 GT:AD:DP:RGQ ./.:0:0:0 chr1 11089 . C . . . AN=352;DP=234 GT:AD:DP:RGQ ./.:0:0:0 chr1 11090 . A . . . AN=272;DP=235 GT:AD:DP:RGQ ./.:0:0:0 chr1 11091 . C . . . AN=352;DP=238 GT:AD:DP:RGQ ./.:0:0:0 chr1 11092 . G . . . AN=364;DP=243 GT:AD:DP:RGQ ./.:0:0:0 chr1 11093 . C . . . AN=358;DP=244 GT:AD:DP:RGQ ./.:0:0:0 chr1 11094 . G . . . AN=372;DP=251 GT:AD:DP:RGQ ./.:0:0:0 chr1 11095 . C . . . AN=364;DP=251 GT:AD:DP:RGQ ./.:0:0:0 chr1 11096 . A . . . AN=294;DP=251 GT:AD:DP:RGQ ./.:0:0:0 chr1 11097 . G . . . AN=392;DP=259 GT:AD:DP:RGQ ./.:0:0:0 chr1 11098 . A . . . AN=304;DP=261 GT:AD:DP:RGQ ./.:0:0:0 chr1 11099 . A . . . AN=276;DP=262 GT:AD:DP:RGQ ./.:0:0:0 chr1 11100 . A . . . AN=218;DP=262 GT:AD:DP:RGQ ./.:0:0:0 chr1 11101 . C . . . AN=384;DP=267 GT:AD:DP:RGQ ./.:0:0:0 chr1 11102 . T . . . AN=276;DP=272 GT:AD:DP:RGQ ./.:0:0:0 chr1 11103 . C . . . AN=392;DP=277 GT:AD:DP:RGQ ./.:0:0:0 chr1 11104 . A . . . AN=242;DP=279 GT:AD:DP:RGQ ./.:0:0:0 chr1 11105 . C . . . AN=398;DP=283 GT:AD:DP:RGQ ./.:0:0:0 chr1 11106 . G . . . AN=416;DP=290 GT:AD:DP:RGQ ./.:0:0:0 chr1 11107 . T . . . AN=300;DP=291 GT:AD:DP:RGQ ./.:0:0:0 chr1 11108 . C . . . AN=394;DP=297 GT:AD:DP:RGQ ./.:0:0:0 chr1 11109 . A . . . AN=348;DP=301 GT:AD:DP:RGQ ./.:0:0:0 chr1 11110 . C . . . AN=404;DP=302 GT:AD:DP:RGQ ./.:0:0:0 chr1 11111 . G . . . AN=438;DP=313 GT:AD:DP:RGQ ./.:0:0:0 chr1 11112 . G . . . AN=438;DP=314 GT:AD:DP:RGQ ./.:0:0:0 chr1 11113 . T . . . AN=326;DP=318 GT:AD:DP:RGQ ./.:0:0:0 chr1 11114 . G . . . AN=460;DP=323 GT:AD:DP:RGQ ./.:0:0:0 chr1 11115 . G . . . AN=444;DP=325 GT:AD:DP:RGQ ./.:0:0:0 chr1 11116 . C . . . AN=406;DP=325 GT:AD:DP:RGQ ./.:0:0:0 chr1 11117 . G . . . AN=458;DP=330 GT:AD:DP:RGQ ./.:0:0:0 chr1 11118 . C . . . AN=450;DP=328 GT:AD:DP:RGQ ./.:0:0:0 chr1 11119 . G . . . AN=482;DP=329 GT:AD:DP:RGQ ./.:0:0:0 chr1 11120 . G . . . AN=482;DP=330 GT:AD:DP:RGQ ./.:0:0:0 chr1 11121 . C . . . AN=488;DP=334 GT:AD:DP:RGQ ./.:0:0:0 chr1 11122 . G . . . AN=490;DP=337 GT:AD:DP:RGQ ./.:0:0:0 chr1 11123 . C . . . AN=484;DP=341 GT:AD:DP:RGQ ./.:0:0:0 chr1 11124 . A . . . AN=468;DP=343 GT:AD:DP:RGQ ./.:0:0:0 chr1 11125 . G . . . AN=480;DP=344 GT:AD:DP:RGQ ./.:0:0:0 chr1 11126 . A . . . AN=460;DP=346 GT:AD:DP:RGQ ./.:0:0:0 chr1 11127 . G . . . AN=496;DP=351 GT:AD:DP:RGQ ./.:0:0:0 chr1 11128 . A . . . AN=466;DP=351 GT:AD:DP:RGQ ./.:0:0:0 chr1 11129 . C . . . AN=494;DP=353 GT:AD:DP:RGQ ./.:0:0:0 chr1 11130 . G . . . AN=500;DP=355 GT:AD:DP:RGQ ./.:0:0:0 chr1 11131 . G . . . AN=498;DP=357 GT:AD:DP:RGQ ./.:0:0:0 chr1 11132 . G . . . AN=498;DP=359 GT:AD:DP:RGQ ./.:0:0:0 chr1 11133 . T . . . AN=476;DP=361 GT:AD:DP:RGQ ./.:0:0:0 chr1 11134 . A . . . AN=442;DP=361 GT:AD:DP:RGQ ./.:0:0:0 chr1 11135 . G . . . AN=490;DP=361 GT:AD:DP:RGQ ./.:0:0:0 chr1 11136 . A . . . AN=482;DP=362 GT:AD:DP:RGQ ./.:0:0:0 chr1 11137 . A . . . AN=428;DP=364 GT:AD:DP:RGQ ./.:0:0:0 chr1 11138 . C . . . AN=498;DP=365 GT:AD:DP:RGQ ./.:0:0:0 chr1 11139 . C . . . AN=502;DP=367 GT:AD:DP:RGQ ./.:0:0:0 chr1 11140 . T . . . AN=468;DP=367 GT:AD:DP:RGQ ./.:0:0:0 chr1 11141 . C . . . AN=506;DP=369 GT:AD:DP:RGQ ./.:0:0:0 chr1 11142 . A . . . AN=488;DP=368 GT:AD:DP:RGQ ./.:0:0:0 chr1 11143 . G . . . AN=510;DP=368 GT:AD:DP:RGQ ./.:0:0:0 chr1 11144 . T . . . AN=486;DP=376 GT:AD:DP:RGQ ./.:0:0:0 chr1 11145 . A . . . AN=508;DP=380 GT:AD:DP:RGQ ./.:0:0:0 chr1 11146 . A . . . AN=496;DP=382 GT:AD:DP:RGQ ./.:0:0:0 chr1 11147 . T . . . AN=452;DP=386 GT:AD:DP:RGQ ./.:0:0:0 chr1 11148 . C . . . AN=522;DP=385 GT:AD:DP:RGQ ./.:0:0:0 chr1 11149 . C . . . AN=516;DP=390 GT:AD:DP:RGQ ./.:0:0:0 chr1 11150 . G . . . AN=526;DP=393 GT:AD:DP:RGQ ./.:0:0:0 chr1 11151 . A . . . AN=504;DP=395 GT:AD:DP:RGQ ./.:0:0:0 chr1 11152 . A . . . AN=514;DP=392 GT:AD:DP:RGQ ./.:0:0:0 chr1 11153 . A . . . AN=466;DP=394 GT:AD:DP:RGQ ./.:0:0:0 chr1 11154 . A . . . AN=470;DP=394 GT:AD:DP:RGQ ./.:0:0:0 chr1 11155 . G . . . AN=526;DP=398 GT:AD:DP:RGQ ./.:0:0:0 chr1 11156 . C . . . AN=518;DP=398 GT:AD:DP:RGQ ./.:0:0:0 chr1 11157 . C . . . AN=520;DP=400 GT:AD:DP:RGQ ./.:0:0:0 chr1 11158 . G . . . AN=528;DP=401 GT:AD:DP:RGQ ./.:0:0:0 chr1 11159 . G . . . AN=526;DP=404 GT:AD:DP:RGQ ./.:0:0:0 chr1 11160 . G . . . AN=518;DP=406 GT:AD:DP:RGQ ./.:0:0:0 chr1 11161 . A . . . AN=510;DP=405 GT:AD:DP:RGQ ./.:0:0:0 chr1 11162 . T . . . AN=492;DP=405 GT:AD:DP:RGQ ./.:0:0:0 chr1 11163 . C . . . AN=524;DP=407 GT:AD:DP:RGQ ./.:0:0:0 chr1 11164 . G . . . AN=526;DP=405 GT:AD:DP:RGQ ./.:0:0:0 chr1 11165 . A . . . AN=450;DP=404 GT:AD:DP:RGQ ./.:0:0:0 chr1 11166 . C . . . AN=526;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11167 . C . . . AN=524;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11168 . G . . . AN=528;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11169 . C . . . AN=530;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11170 . C . . . AN=522;DP=410 GT:AD:DP:RGQ ./.:0:0:0 chr1 11171 . C . . . AN=524;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11172 . C . . . AN=518;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11173 . T . . . AN=494;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11174 . T . . . AN=498;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11175 . G . . . AN=520;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11176 . C . . . AN=516;DP=412 GT:AD:DP:RGQ ./.:0:0:0 chr1 11177 . T . . . AN=492;DP=412 GT:AD:DP:RGQ ./.:0:0:0 chr1 11178 . T . . . AN=494;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11179 . G . . . AN=516;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11180 . C . . . AN=516;DP=412 GT:AD:DP:RGQ ./.:0:0:0 chr1 11181 . A . . . AN=488;DP=408 GT:AD:DP:RGQ ./.:0:0:0 chr1 11182 . G . . . AN=514;DP=407 GT:AD:DP:RGQ ./.:0:0:0 chr1 11183 . C . . . AN=506;DP=405 GT:AD:DP:RGQ ./.:0:0:0 chr1 11184 . C . . . AN=508;DP=406 GT:AD:DP:RGQ ./.:0:0:0 chr1 11185 . G . . . AN=502;DP=405 GT:AD:DP:RGQ ./.:0:0:0 chr1 11186 . G . . . AN=512;DP=407 GT:AD:DP:RGQ ./.:0:0:0 chr1 11187 . G . . . AN=508;DP=407 GT:AD:DP:RGQ ./.:0:0:0 chr1 11188 . C . . . AN=510;DP=407 GT:AD:DP:RGQ ./.:0:0:0 chr1 11189 . A . . . AN=502;DP=407 GT:AD:DP:RGQ ./.:0:0:0 chr1 11190 . C . . . AN=504;DP=408 GT:AD:DP:RGQ ./.:0:0:0 chr1 11191 . T . . . AN=482;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11192 . A . . . AN=484;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11193 . C . . . AN=508;DP=411 GT:AD:DP:RGQ ./.:0:0:0 chr1 11194 . A . . . AN=478;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11195 . G . . . AN=492;DP=410 GT:AD:DP:RGQ ./.:0:0:0 chr1 11196 . G . . . AN=490;DP=410 GT:AD:DP:RGQ ./.:0:0:0 chr1 11197 . A . . . AN=436;DP=409 GT:AD:DP:RGQ ./.:0:0:0 chr1 11198 . C . . . AN=472;DP=408 GT:AD:DP:RGQ ./.:0:0:0 chr1 11199 . C . . . AN=488;DP=408 GT:AD:DP:RGQ ./.:0:0:0 chr1 11200 . C . . . AN=468;DP=402 GT:AD:DP:RGQ ./.:0:0:0 chr1 11201 . G . . . AN=472;DP=399 GT:AD:DP:RGQ ./.:0:0:0 chr1 11202 . C . . . AN=472;DP=394 GT:AD:DP:RGQ ./.:0:0:0 chr1 11203 . T . . . AN=420;DP=393 GT:AD:DP:RGQ ./.:0:0:0 chr1 11204 . T . . . AN=430;DP=391 GT:AD:DP:RGQ ./.:0:0:0 chr1 11205 . G . . . AN=450;DP=383 GT:AD:DP:RGQ ./.:0:0:0 chr1 11206 . C . . . AN=448;DP=380 GT:AD:DP:RGQ ./.:0:0:0 chr1 11207 . T . . . AN=420;DP=379 GT:AD:DP:RGQ ./.:0:0:0 chr1 11208 . C . . . AN=442;DP=378 GT:AD:DP:RGQ ./.:0:0:0 chr1 11209 . A . . . AN=420;DP=373 GT:AD:DP:RGQ ./.:0:0:0 chr1 11210 . C . . . AN=424;DP=368 GT:AD:DP:RGQ ./.:0:0:0 chr1 11211 . G . . . AN=430;DP=361 GT:AD:DP:RGQ ./.:0:0:0 chr1 11212 . G . . . AN=428;DP=359 GT:AD:DP:RGQ ./.:0:0:0 chr1 11213 . T . . . AN=414;DP=357 GT:AD:DP:RGQ ./.:0:0:0 chr1 11214 . G . . . AN=420;DP=352 GT:AD:DP:RGQ ./.:0:0:0 chr1 11215 . C . . . AN=416;DP=349 GT:AD:DP:RGQ ./.:0:0:0 chr1 11216 . T . . . AN=396;DP=346 GT:AD:DP:RGQ ./.:0:0:0 chr1 11217 . G . . . AN=418;DP=338 GT:AD:DP:RGQ ./.:0:0:0 chr1 11218 . T . . . AN=388;DP=334 GT:AD:DP:RGQ ./.:0:0:0 chr1 11219 . G . . . AN=416;DP=329 GT:AD:DP:RGQ ./.:0:0:0 chr1 11220 . C . . . AN=410;DP=326 GT:AD:DP:RGQ ./.:0:0:0 chr1 11221 . C . . . AN=404;DP=323 GT:AD:DP:RGQ ./.:0:0:0 chr1 11222 . A . . . AN=388;DP=321 GT:AD:DP:RGQ ./.:0:0:0 chr1 11223 . G . . . AN=404;DP=322 GT:AD:DP:RGQ ./.:0:0:0 chr1 11224 . G . . . AN=404;DP=320 GT:AD:DP:RGQ ./.:0:0:0 chr1 11225 . G . . . AN=402;DP=317 GT:AD:DP:RGQ ./.:0:0:0 chr1 11226 . C . . . AN=398;DP=313 GT:AD:DP:RGQ ./.:0:0:0 chr1 11227 . G . . . AN=394;DP=311 GT:AD:DP:RGQ ./.:0:0:0 chr1 11228 . C . . . AN=392;DP=308 GT:AD:DP:RGQ ./.:0:0:0 chr1 11229 . C . . . AN=374;DP=308 GT:AD:DP:RGQ ./.:0:0:0 chr1 11230 . C . . . AN=374;DP=308 GT:AD:DP:RGQ ./.:0:0:0 chr1 11231 . C . . . AN=362;DP=303 GT:AD:DP:RGQ ./.:0:0:0 chr1 11232 . C . . . AN=364;DP=301 GT:AD:DP:RGQ ./.:0:0:0 chr1 11233 . T . . . AN=350;DP=299 GT:AD:DP:RGQ ./.:0:0:0 chr1 11234 . G . . . AN=368;DP=297 GT:AD:DP:RGQ ./.:0:0:0 chr1 11235 . C . . . AN=360;DP=292 GT:AD:DP:RGQ ./.:0:0:0 chr1 11236 . T . . . AN=340;DP=292 GT:AD:DP:RGQ ./.:0:0:0 chr1 11237 . G . . . AN=350;DP=287 GT:AD:DP:RGQ ./.:0:0:0 chr1 11238 . G . . . AN=350;DP=281 GT:AD:DP:RGQ ./.:0:0:0 chr1 11239 . C . . . AN=348;DP=278 GT:AD:DP:RGQ ./.:0:0:0 chr1 11240 . G . . . AN=350;DP=274 GT:AD:DP:RGQ ./.:0:0:0 chr1 11241 . A . . . AN=312;DP=271 GT:AD:DP:RGQ ./.:0:0:0 chr1 11242 . C . . . AN=330;DP=271 GT:AD:DP:RGQ ./.:0:0:0 chr1 11243 . T . . . AN=318;DP=267 GT:AD:DP:RGQ ./.:0:0:0 chr1 11244 . A . . . AN=324;DP=265 GT:AD:DP:RGQ ./.:0:0:0 chr1 11245 . G . . . AN=328;DP=261 GT:AD:DP:RGQ ./.:0:0:0 chr1 11246 . G . . . AN=314;DP=260 GT:AD:DP:RGQ ./.:0:0:0 chr1 11247 . G . . . AN=314;DP=254 GT:AD:DP:RGQ ./.:0:0:0 chr1 11248 . C . . . AN=312;DP=251 GT:AD:DP:RGQ ./.:0:0:0 chr1 11249 . A . . . AN=304;DP=247 GT:AD:DP:RGQ ./.:0:0:0 chr1 11250 . A . . . AN=288;DP=247 GT:AD:DP:RGQ ./.:0:0:0 chr1 11251 . C . . . AN=286;DP=245 GT:AD:DP:RGQ ./.:0:0:0 chr1 11252 . T . . . AN=268;DP=240 GT:AD:DP:RGQ ./.:0:0:0 chr1 11253 . G . . . AN=284;DP=238 GT:AD:DP:RGQ ./.:0:0:0 chr1 11254 . C . . . AN=274;DP=233 GT:AD:DP:RGQ ./.:0:0:0 chr1 11255 . A . . . AN=258;DP=232 GT:AD:DP:RGQ ./.:0:0:0 chr1 11256 . G . . . AN=258;DP=227 GT:AD:DP:RGQ ./.:0:0:0 chr1 11257 . G . . . AN=258;DP=224 GT:AD:DP:RGQ ./.:0:0:0 chr1 11258 . G . . . AN=246;DP=221 GT:AD:DP:RGQ ./.:0:0:0 chr1 11259 . C . . . AN=242;DP=213 GT:AD:DP:RGQ ./.:0:0:0 chr1 11260 . T . . . AN=230;DP=210 GT:AD:DP:RGQ ./.:0:0:0 chr1 11261 . C . . . AN=242;DP=206 GT:AD:DP:RGQ ./.:0:0:0 chr1 11262 . T . . . AN=234;DP=199 GT:AD:DP:RGQ ./.:0:0:0 chr1 11263 . C . . . AN=244;DP=198 GT:AD:DP:RGQ ./.:0:0:0 chr1 11264 . T . . . AN=226;DP=193 GT:AD:DP:RGQ ./.:0:0:0 chr1 11265 . T . . . AN=226;DP=188 GT:AD:DP:RGQ ./.:0:0:0 chr1 11266 . G . . . AN=234;DP=186 GT:AD:DP:RGQ ./.:0:0:0 chr1 11267 . C . . . AN=232;DP=178 GT:AD:DP:RGQ ./.:0:0:0 chr1 11268 . T . . . AN=214;DP=174 GT:AD:DP:RGQ ./.:0:0:0 chr1 11269 . T . . . AN=216;DP=173 GT:AD:DP:RGQ ./.:0:0:0 chr1 11270 . A . . . AN=212;DP=171 GT:AD:DP:RGQ ./.:0:0:0 chr1 11271 . G . . . AN=218;DP=171 GT:AD:DP:RGQ ./.:0:0:0 chr1 11272 . A . . . AN=194;DP=164 GT:AD:DP:RGQ ./.:0:0:0 chr1 11273 . G . . . AN=208;DP=163 GT:AD:DP:RGQ ./.:0:0:0 chr1 11274 . T . . . AN=204;DP=159 GT:AD:DP:RGQ ./.:0:0:0 chr1 11275 . G . . . AN=204;DP=157 GT:AD:DP:RGQ ./.:0:0:0 chr1 11276 . G . . . AN=206;DP=157 GT:AD:DP:RGQ ./.:0:0:0 chr1 11277 . T . . . AN=196;DP=154 GT:AD:DP:RGQ ./.:0:0:0 chr1 11278 . G . . . AN=202;DP=149 GT:AD:DP:RGQ ./.:0:0:0 chr1 11279 . G . . . AN=200;DP=148 GT:AD:DP:RGQ ./.:0:0:0 chr1 11280 . C . . . AN=192;DP=145 GT:AD:DP:RGQ ./.:0:0:0 chr1 11281 . C . . . AN=188;DP=143 GT:AD:DP:RGQ ./.:0:0:0 chr1 11282 . A . . . AN=178;DP=141 GT:AD:DP:RGQ ./.:0:0:0 chr1 11283 . G . . . AN=190;DP=138 GT:AD:DP:RGQ ./.:0:0:0 chr1 11284 . C . . . AN=190;DP=136 GT:AD:DP:RGQ ./.:0:0:0 chr1 11285 . G . . . AN=166;DP=134 GT:AD:DP:RGQ ./.:0:0:0 chr1 11286 . C . . . AN=160;DP=132 GT:AD:DP:RGQ ./.:0:0:0 chr1 11287 . C . . . AN=150;DP=131 GT:AD:DP:RGQ ./.:0:0:0 chr1 11288 . C . . . AN=156;DP=128 GT:AD:DP:RGQ ./.:0:0:0 chr1 11289 . C . . . AN=136;DP=126 GT:AD:DP:RGQ ./.:0:0:0 chr1 11290 . C . . . AN=136;DP=124 GT:AD:DP:RGQ ./.:0:0:0 chr1 11291 . T . . . AN=124;DP=123 GT:AD:DP:RGQ ./.:0:0:0 chr1 11292 . G . . . AN=136;DP=120 GT:AD:DP:RGQ ./.:0:0:0 chr1 11293 . C . . . AN=128;DP=118 GT:AD:DP:RGQ ./.:0:0:0 chr1 11294 . T . . . AN=110;DP=118 GT:AD:DP:RGQ ./.:0:0:0 chr1 11295 . G . . . AN=126;DP=110 GT:AD:DP:RGQ ./.:0:0:0 chr1 11296 . G . . . AN=126;DP=102 GT:AD:DP:RGQ ./.:0:0:0 chr1 11297 . C . . . AN=122;DP=101 GT:AD:DP:RGQ ./.:0:0:0 chr1 11298 . G . . . AN=122;DP=99 GT:AD:DP:RGQ ./.:0:0:0 chr1 11299 . C . . . AN=118;DP=98 GT:AD:DP:RGQ ./.:0:0:0 chr1 11300 . C . . . AN=114;DP=93 GT:AD:DP:RGQ ./.:0:0:0 chr1 11301 . G . . . AN=118;DP=89 GT:AD:DP:RGQ ./.:0:0:0 chr1 11302 . G . . . AN=104;DP=87 GT:AD:DP:RGQ ./.:0:0:0 chr1 11303 . G . . . AN=104;DP=87 GT:AD:DP:RGQ ./.:0:0:0 chr1 11304 . G . . . AN=104;DP=83 GT:AD:DP:RGQ ./.:0:0:0 chr1 11305 . C . . . AN=102;DP=81 GT:AD:DP:RGQ ./.:0:0:0 chr1 11306 . A . . . AN=100;DP=80 GT:AD:DP:RGQ ./.:0:0:0 chr1 11307 . C . . . AN=98;DP=80 GT:AD:DP:RGQ ./.:0:0:0 chr1 11308 . T . . . AN=88;DP=78 GT:AD:DP:RGQ ./.:0:0:0 chr1 11309 . G . . . AN=98;DP=77 GT:AD:DP:RGQ ./.:0:0:0 chr1 11310 . C . . . AN=98;DP=74 GT:AD:DP:RGQ ./.:0:0:0 chr1 11311 . A . . . AN=88;DP=72 GT:AD:DP:RGQ ./.:0:0:0 chr1 11312 . G . . . AN=96;DP=70 GT:AD:DP:RGQ ./.:0:0:0 chr1 11313 . G . . . AN=96;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 11314 . G . . . AN=92;DP=67 GT:AD:DP:RGQ ./.:0:0:0 chr1 11315 . C . . . AN=88;DP=65 GT:AD:DP:RGQ ./.:0:0:0 chr1 11316 . C . . . AN=86;DP=63 GT:AD:DP:RGQ ./.:0:0:0 chr1 11317 . C . . . AN=88;DP=61 GT:AD:DP:RGQ ./.:0:0:0 chr1 11318 . T . . . AN=84;DP=60 GT:AD:DP:RGQ ./.:0:0:0 chr1 11319 . C . . . AN=88;DP=60 GT:AD:DP:RGQ ./.:0:0:0 chr1 11320 . T . . . AN=84;DP=59 GT:AD:DP:RGQ ./.:0:0:0 chr1 11321 . T . . . AN=80;DP=59 GT:AD:DP:RGQ ./.:0:0:0 chr1 11322 . G . . . AN=88;DP=58 GT:AD:DP:RGQ ./.:0:0:0 chr1 11323 . C . . . AN=84;DP=58 GT:AD:DP:RGQ ./.:0:0:0 chr1 11324 . T . . . AN=84;DP=56 GT:AD:DP:RGQ ./.:0:0:0 chr1 11325 . T . . . AN=76;DP=56 GT:AD:DP:RGQ ./.:0:0:0 chr1 11326 . A . . . AN=68;DP=55 GT:AD:DP:RGQ ./.:0:0:0 chr1 11327 . C . . . AN=76;DP=54 GT:AD:DP:RGQ ./.:0:0:0 chr1 11328 . T . . . AN=70;DP=55 GT:AD:DP:RGQ ./.:0:0:0 chr1 11329 . G . . . AN=74;DP=55 GT:AD:DP:RGQ ./.:0:0:0 chr1 11330 . T . . . AN=70;DP=53 GT:AD:DP:RGQ ./.:0:0:0 chr1 11331 . A . . . AN=62;DP=53 GT:AD:DP:RGQ ./.:0:0:0 chr1 11332 . T . . . AN=58;DP=53 GT:AD:DP:RGQ ./.:0:0:0 chr1 11333 . A . . . AN=60;DP=51 GT:AD:DP:RGQ ./.:0:0:0 chr1 11334 . G . . . AN=54;DP=51 GT:AD:DP:RGQ ./.:0:0:0 chr1 11335 . T . . . AN=44;DP=48 GT:AD:DP:RGQ ./.:0:0:0 chr1 11336 . G . . . AN=54;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 11337 . G . . . AN=52;DP=44 GT:AD:DP:RGQ ./.:0:0:0 chr1 11338 . T . . . AN=50;DP=43 GT:AD:DP:RGQ ./.:0:0:0 chr1 11339 . G . . . AN=50;DP=42 GT:AD:DP:RGQ ./.:0:0:0 chr1 11340 . G . . . AN=50;DP=41 GT:AD:DP:RGQ ./.:0:0:0 chr1 11341 . C . . . AN=48;DP=39 GT:AD:DP:RGQ ./.:0:0:0 chr1 11342 . A . . . AN=36;DP=36 GT:AD:DP:RGQ ./.:0:0:0 chr1 11343 . C . . . AN=46;DP=35 GT:AD:DP:RGQ ./.:0:0:0 chr1 11344 . G . . . AN=46;DP=32 GT:AD:DP:RGQ ./.:0:0:0 chr1 11345 . C . . . AN=46;DP=31 GT:AD:DP:RGQ ./.:0:0:0 chr1 11346 . C . . . AN=46;DP=30 GT:AD:DP:RGQ ./.:0:0:0 chr1 11347 . G . . . AN=44;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 11348 . C . . . AN=44;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 11349 . C . . . AN=38;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 11350 . T . . . AN=40;DP=28 GT:AD:DP:RGQ ./.:0:0:0 chr1 11351 . G . . . AN=42;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 11352 . C . . . AN=42;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 11353 . T . . . AN=38;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 11354 . G . . . AN=40;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 11355 . G . . . AN=38;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 11356 . C . . . AN=38;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 11357 . A . . . AN=34;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 11358 . G . . . AN=38;DP=26 GT:AD:DP:RGQ ./.:0:0:0 chr1 11359 . C . . . AN=34;DP=25 GT:AD:DP:RGQ ./.:0:0:0 chr1 11360 . T . . . AN=34;DP=24 GT:AD:DP:RGQ ./.:0:0:0 chr1 11361 . A . . . AN=32;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11362 . G . . . AN=34;DP=24 GT:AD:DP:RGQ ./.:0:0:0 chr1 11363 . G . . . AN=32;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11364 . G . . . AN=32;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11365 . A . . . AN=28;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11366 . C . . . AN=28;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11367 . A . . . AN=22;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11368 . T . . . AN=28;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11369 . T . . . AN=28;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 11370 . G . . . AN=28;DP=22 GT:AD:DP:RGQ ./.:0:0:0 chr1 11371 . C . . . AN=28;DP=20 GT:AD:DP:RGQ ./.:0:0:0 chr1 11372 . A . . . AN=26;DP=19 GT:AD:DP:RGQ ./.:0:0:0 chr1 11373 . G . . . AN=28;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 11374 . G . . . AN=28;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 11375 . G . . . AN=28;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 11376 . T . . . AN=26;DP=16 GT:AD:DP:RGQ ./.:0:0:0 chr1 11377 . C . . . AN=28;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11378 . C . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11379 . T . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11380 . C . . . AN=24;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11381 . T . . . AN=20;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11382 . T . . . AN=22;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11383 . G . . . AN=22;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11384 . C . . . AN=22;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11385 . T . . . AN=18;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11386 . C . . . AN=22;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11387 . A . . . AN=20;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 11388 . A . . . AN=22;DP=13 GT:AD:DP:RGQ ./.:0:0:0 chr1 11389 . G . . . AN=20;DP=13 GT:AD:DP:RGQ ./.:0:0:0 chr1 11390 . G . . . AN=20;DP=12 GT:AD:DP:RGQ ./.:0:0:0 chr1 11391 . T . . . AN=16;DP=12 GT:AD:DP:RGQ ./.:0:0:0 chr1 11392 . G . . . AN=18;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11393 . T . . . AN=16;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11394 . A . . . AN=16;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11395 . G . . . AN=16;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11396 . T . . . AN=16;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11397 . G . . . AN=14;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11398 . G . . . AN=16;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 11399 . C . . . AN=14;DP=10 GT:AD:DP:RGQ ./.:0:0:0 chr1 11400 . A . . . AN=14;DP=10 GT:AD:DP:RGQ ./.:0:0:0 chr1 11401 . G . . . AN=14;DP=10 GT:AD:DP:RGQ ./.:0:0:0 chr1 11402 . C . . . AN=14;DP=10 GT:AD:DP:RGQ ./.:0:0:0 chr1 11403 . A . . . AN=10;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 11404 . C . . . AN=12;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 11405 . G . . . AN=12;DP=8 GT:AD:DP:RGQ ./.:0:0:0 chr1 11406 . C . . . AN=12;DP=8 GT:AD:DP:RGQ ./.:0:0:0 chr1 11407 . C . . . AN=12;DP=8 GT:AD:DP:RGQ ./.:0:0:0 chr1 11408 . C . . . AN=10;DP=8 GT:AD:DP:RGQ ./.:0:0:0 chr1 11409 . A . . . AN=8;DP=8 GT:AD:DP:RGQ ./.:0:0:0 chr1 11410 . C . . . AN=12;DP=7 GT:AD:DP:RGQ ./.:0:0:0 chr1 11411 . C . . . AN=12;DP=7 GT:AD:DP:RGQ ./.:0:0:0 chr1 11412 . T . . . AN=12;DP=7 GT:AD:DP:RGQ ./.:0:0:0 chr1 11413 . G . . . AN=10;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11414 . C . . . AN=10;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11415 . T . . . AN=10;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11416 . G . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11417 . G . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11418 . C . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11419 . A . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11420 . G . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11421 . C . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11422 . T . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11423 . G . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11424 . G . . . AN=8;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 11425 . G . . . AN=8;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 11426 . G . . . AN=8;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 11427 . A . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11428 . C . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11429 . A . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11430 . C . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11431 . T . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11432 . G . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11433 . C . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11434 . C . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11435 . G . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11436 . G . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11437 . G . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11438 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11439 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11440 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11441 . T . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11442 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11443 . T . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11444 . T . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11445 . G . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11446 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11447 . T . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11448 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11449 . C . . . AN=6;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 11450 . A . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11451 . A . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11452 . C . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11453 . A . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11454 . G . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11455 . T . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11456 . A . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11457 . C . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11458 . T . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11459 . G . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11460 . G . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11461 . C . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11462 . G . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11463 . G . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11464 . A . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11465 . T . . . AN=2;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11466 . T . . . AN=2;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11467 . A . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11468 . T . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11469 . A . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11470 . G . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11471 . G . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11472 . G . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11473 . A . . . AN=4;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 11474 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11475 . A . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11476 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11477 . A . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11478 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11479 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11480 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11481 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11482 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11483 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11484 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11485 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11486 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11487 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11488 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11489 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11490 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11491 . C . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11492 . T . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11493 . G . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11494 . T . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11495 . T . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11496 . T . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11497 . G . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11498 . G . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11499 . T . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11500 . C . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11501 . T . . . AN=2;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 11502 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11503 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11504 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11505 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11506 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11507 . G . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11508 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11509 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11510 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11511 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11512 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11513 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11514 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11515 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11516 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11517 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11518 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11519 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11520 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11521 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11522 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11523 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11524 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11525 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11526 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11527 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11528 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11529 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11530 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11531 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11532 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11533 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11534 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11535 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11536 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11537 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11538 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11539 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11540 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11541 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11542 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11543 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11544 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11545 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11546 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11547 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11548 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11549 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11550 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11551 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11552 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11553 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11554 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11555 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11556 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11557 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11558 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11559 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11560 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11561 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11562 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11563 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11564 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11565 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11566 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11567 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11568 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11569 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11570 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11571 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11572 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11573 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11574 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11575 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11576 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11577 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11578 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11579 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11580 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11581 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11582 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11583 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11584 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11585 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11586 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11587 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11588 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11589 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11590 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11591 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11592 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11593 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11594 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11595 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11596 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11597 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11598 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11599 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11600 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11601 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11602 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11603 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11604 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11605 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11606 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11607 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11608 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11609 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11610 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11611 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11612 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11613 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11614 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11615 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11616 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11617 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11618 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11619 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11620 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11621 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11622 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11623 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11624 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11625 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11626 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11627 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11628 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11629 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11630 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11631 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11632 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11633 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11634 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11635 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11636 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11637 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11638 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11639 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11640 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11641 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11642 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11643 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11644 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11645 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11646 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11647 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11648 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11649 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11650 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11651 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11652 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11653 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11654 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11655 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11656 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11657 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11658 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11659 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11660 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11661 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11662 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11663 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11664 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11665 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11666 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11667 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11668 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11669 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11670 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11671 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11672 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11673 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11674 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11675 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11676 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11677 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11678 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11679 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11680 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11681 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11682 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11683 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11684 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11685 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11686 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11687 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11688 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11689 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11690 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11691 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11692 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11693 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11694 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11695 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11696 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11697 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11698 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11699 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11700 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11701 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11702 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11703 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11704 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11705 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11706 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11707 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11708 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11709 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11710 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11711 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11712 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11713 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11714 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11715 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11716 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11717 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11718 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11719 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11720 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11721 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11722 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11723 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11724 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11725 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11726 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11727 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11728 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11729 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11730 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11731 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11732 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11733 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11734 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11735 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11736 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11737 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11738 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11739 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11740 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11741 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11742 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11743 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11744 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11745 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11746 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11747 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11748 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11749 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11750 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11751 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11752 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11753 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11754 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11755 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11756 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11757 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11758 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11759 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11760 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11761 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11762 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11763 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11764 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11765 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11766 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11767 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11768 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11769 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11770 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11771 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11772 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11773 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11774 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11775 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11776 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11777 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11778 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11779 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11780 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11781 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11782 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11783 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11784 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11785 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11786 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11787 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11788 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11789 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11790 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11791 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11792 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11793 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11794 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11795 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11796 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11797 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11798 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11799 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11800 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11801 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11802 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11803 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11804 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11805 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11806 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11807 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11808 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11809 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11810 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11811 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11812 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11813 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11814 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11815 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11816 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11817 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11818 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11819 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11820 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11821 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11822 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11823 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11824 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11825 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11826 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11827 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11828 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11829 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11830 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11831 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11832 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11833 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11834 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11835 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11836 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11837 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11838 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11839 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11840 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11841 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11842 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11843 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11844 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11845 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11846 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11847 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11848 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11849 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11850 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11851 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11852 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11853 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11854 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11855 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11856 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11857 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11858 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11859 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 11860 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11861 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11862 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11863 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11864 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11865 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11866 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11867 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11868 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11869 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11870 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11871 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11872 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11873 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11874 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11875 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11876 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11877 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11878 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11879 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11880 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11881 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11882 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11883 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11884 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11885 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11886 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11887 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11888 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11889 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11890 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11891 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11892 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11893 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11894 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11895 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11896 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11897 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11898 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11899 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11900 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11901 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11902 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11903 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11904 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11905 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11906 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11907 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11908 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11909 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11910 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11911 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11912 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11913 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11914 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11915 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11916 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11917 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11918 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11919 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11920 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11921 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11922 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11923 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11924 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11925 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11926 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11927 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11928 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11929 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11930 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11931 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11932 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11933 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11934 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11935 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11936 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11937 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11938 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11939 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11940 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11941 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11942 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11943 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11944 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11945 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11946 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11947 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11948 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11949 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11950 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11951 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11952 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11953 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11954 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11955 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11956 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11957 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11958 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11959 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11960 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11961 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11962 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11963 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11964 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11965 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11966 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11967 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11968 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11969 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11970 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11971 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11972 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11973 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11974 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11975 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11976 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11977 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11978 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11979 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11980 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11981 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11982 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11983 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11984 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11985 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11986 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11987 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11988 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11989 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11990 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11991 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11992 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11993 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11994 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11995 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11996 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11997 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11998 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 11999 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12000 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12001 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12002 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12003 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12004 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12005 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12006 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12007 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12008 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12009 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12010 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12011 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12012 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12013 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12014 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12015 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12016 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12017 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12018 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12019 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12020 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12021 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12022 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12023 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12024 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12025 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12026 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12027 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12028 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12029 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12030 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12031 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12032 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12033 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12034 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12035 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12036 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12037 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12038 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12039 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12040 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12041 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12042 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12043 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12044 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12045 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12046 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12047 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12048 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12049 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12050 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12051 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12052 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12053 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12054 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12055 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12056 . A . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12057 . G . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12058 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12059 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12060 . C . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12061 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12062 . G . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12063 . G . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12064 . A . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12065 . G . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12066 . T . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12067 . G . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12068 . G . . . DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12069 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12070 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12071 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12072 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12073 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12074 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12075 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12076 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12077 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12078 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12079 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12080 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12081 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12082 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12083 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12084 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12085 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12086 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12087 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12088 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12089 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12090 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12091 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12092 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12093 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12094 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12095 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12096 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12097 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12098 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12099 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12100 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12101 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12102 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12103 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12104 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12105 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12106 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12107 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12108 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12109 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12110 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12111 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12112 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12113 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12114 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12115 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12116 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12117 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12118 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12119 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12120 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12121 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12122 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12123 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12124 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12125 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12126 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12127 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12128 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12129 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12130 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12131 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12132 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12133 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12134 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12135 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12136 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12137 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12138 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12139 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12140 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12141 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12142 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12143 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12144 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12145 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12146 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12147 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12148 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12149 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12150 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12151 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12152 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12153 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12154 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12155 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12156 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12157 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12158 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12159 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12160 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12161 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12162 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12163 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12164 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12165 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12166 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12167 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12168 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12169 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12170 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12171 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12172 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12173 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12174 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12175 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12176 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12177 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12178 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12179 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12180 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12181 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12182 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12183 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12184 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12185 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12186 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12187 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12188 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12189 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12190 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12191 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12192 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12193 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12194 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12195 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12196 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12197 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12198 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12199 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12200 . G . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12201 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12202 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12203 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12204 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12205 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12206 . A . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12207 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12208 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12209 . T . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12210 . C . . . . GT:AD:DP:RGQ ./.:0:0:0 chr1 12211 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12212 . C . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12213 . T . . . AN=2;DP=1 GT:AD:DP:RGQ ./.:0:0:0 chr1 12214 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12215 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12216 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12217 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12218 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12219 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12220 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12221 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12222 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12223 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12224 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12225 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12226 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12227 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12228 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12229 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12230 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12231 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12232 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12233 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12234 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12235 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12236 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12237 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12238 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12239 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12240 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12241 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12242 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12243 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12244 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12245 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12246 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12247 . A . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12248 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12249 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12250 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12251 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12252 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12253 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12254 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12255 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12256 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12257 . C . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12258 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12259 . G . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12260 . T . . . AN=4;DP=2 GT:AD:DP:RGQ ./.:0:0:0 chr1 12261 . G . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 12262 . A . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 12263 . T . . . AN=6;DP=3 GT:AD:DP:RGQ ./.:0:0:0 chr1 12264 . A . . . AN=8;DP=4 GT:AD:DP:RGQ ./.:0:0:0 chr1 12265 . C . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12266 . G . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12267 . T . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12268 . G . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12269 . G . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12270 . C . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12271 . C . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12272 . G . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12273 . G . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12274 . C . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12275 . C . . . AN=10;DP=5 GT:AD:DP:RGQ ./.:0:0:0 chr1 12276 . C . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12277 . T . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12278 . C . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12279 . G . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12280 . C . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12281 . T . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12282 . C . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12283 . C . . . AN=12;DP=6 GT:AD:DP:RGQ ./.:0:0:0 chr1 12284 . A . . . AN=12;DP=7 GT:AD:DP:RGQ ./.:0:0:0 chr1 12285 . G . . . AN=14;DP=7 GT:AD:DP:RGQ ./.:0:0:0 chr1 12286 . C . . . AN=16;DP=8 GT:AD:DP:RGQ ./.:0:0:0 chr1 12287 . A . . . AN=14;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12288 . G . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12289 . C . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12290 . T . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12291 . G . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12292 . G . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12293 . A . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12294 . C . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12295 . C . . . AN=16;DP=9 GT:AD:DP:RGQ ./.:0:0:0 chr1 12296 . C . . . AN=20;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 12297 . C . . . AN=20;DP=11 GT:AD:DP:RGQ ./.:0:0:0 chr1 12298 . T . . . AN=22;DP=12 GT:AD:DP:RGQ ./.:0:0:0 chr1 12299 . A . . . AN=20;DP=12 GT:AD:DP:RGQ ./.:0:0:0 chr1 12300 . C . . . AN=22;DP=12 GT:AD:DP:RGQ ./.:0:0:0 chr1 12301 . C . . . AN=22;DP=12 GT:AD:DP:RGQ ./.:0:0:0 chr1 12302 . T . . . AN=22;DP=13 GT:AD:DP:RGQ ./.:0:0:0 chr1 12303 . G . . . AN=24;DP=13 GT:AD:DP:RGQ ./.:0:0:0 chr1 12304 . C . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12305 . C . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12306 . G . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12307 . T . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12308 . C . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12309 . T . . . AN=24;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12310 . G . . . AN=26;DP=14 GT:AD:DP:RGQ ./.:0:0:0 chr1 12311 . C . . . AN=28;DP=15 GT:AD:DP:RGQ ./.:0:0:0 chr1 12312 . T . . . AN=28;DP=15 GT:AD:DP:RGQ ./.:0:0:0 chr1 12313 . G . . . AN=28;DP=15 GT:AD:DP:RGQ ./.:0:0:0 chr1 12314 . C . . . AN=28;DP=15 GT:AD:DP:RGQ ./.:0:0:0 chr1 12315 . C . . . AN=28;DP=15 GT:AD:DP:RGQ ./.:0:0:0 chr1 12316 . A . . . AN=28;DP=15 GT:AD:DP:RGQ ./.:0:0:0 chr1 12317 . T . . . AN=26;DP=16 GT:AD:DP:RGQ ./.:0:0:0 chr1 12318 . C . . . AN=28;DP=16 GT:AD:DP:RGQ ./.:0:0:0 chr1 12319 . G . . . AN=28;DP=16 GT:AD:DP:RGQ ./.:0:0:0 chr1 12320 . G . . . AN=28;DP=16 GT:AD:DP:RGQ ./.:0:0:0 chr1 12321 . A . . . AN=30;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 12322 . G . . . AN=30;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 12323 . C . . . AN=30;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 12324 . C . . . AN=30;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 12325 . C . . . AN=30;DP=17 GT:AD:DP:RGQ ./.:0:0:0 chr1 12326 . A . . . AN=32;DP=18 GT:AD:DP:RGQ ./.:0:0:0 chr1 12327 . A . . . AN=32;DP=19 GT:AD:DP:RGQ ./.:0:0:0 chr1 12328 . A . . . AN=34;DP=19 GT:AD:DP:RGQ ./.:0:0:0 chr1 12329 . G . . . AN=36;DP=20 GT:AD:DP:RGQ ./.:0:0:0 chr1 12330 . C . . . AN=38;DP=21 GT:AD:DP:RGQ ./.:0:0:0 chr1 12331 . C . . . AN=38;DP=21 GT:AD:DP:RGQ ./.:0:0:0 chr1 12332 . G . . . AN=34;DP=21 GT:AD:DP:RGQ ./.:0:0:0 chr1 12333 . G . . . AN=38;DP=21 GT:AD:DP:RGQ ./.:0:0:0 chr1 12334 . G . . . AN=38;DP=21 GT:AD:DP:RGQ ./.:0:0:0 chr1 12335 . C . . . AN=38;DP=21 GT:AD:DP:RGQ ./.:0:0:0 chr1 12336 . T . . . AN=40;DP=22 GT:AD:DP:RGQ ./.:0:0:0 chr1 12337 . G . . . AN=42;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 12338 . T . . . AN=38;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 12339 . G . . . AN=40;DP=23 GT:AD:DP:RGQ ./.:0:0:0 chr1 12340 . A . . . AN=38;DP=24 GT:AD:DP:RGQ ./.:0:0:0 chr1 12341 . C . . . AN=44;DP=24 GT:AD:DP:RGQ ./.:0:0:0 chr1 12342 . T . . . AN=44;DP=24 GT:AD:DP:RGQ ./.:0:0:0 chr1 12343 . G . . . AN=48;DP=26 GT:AD:DP:RGQ ./.:0:0:0 chr1 12344 . C . . . AN=50;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 12345 . T . . . AN=48;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 12346 . C . . . AN=50;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 12347 . A . . . AN=50;DP=27 GT:AD:DP:RGQ ./.:0:0:0 chr1 12348 . G . . . AN=50;DP=28 GT:AD:DP:RGQ ./.:0:0:0 chr1 12349 . A . . . AN=50;DP=28 GT:AD:DP:RGQ ./.:0:0:0 chr1 12350 . C . . . AN=52;DP=28 GT:AD:DP:RGQ ./.:0:0:0 chr1 12351 . C . . . AN=52;DP=28 GT:AD:DP:RGQ ./.:0:0:0 chr1 12352 . A . . . AN=50;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 12353 . G . . . AN=50;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 12354 . C . . . AN=50;DP=29 GT:AD:DP:RGQ ./.:0:0:0 chr1 12355 . C . . . AN=52;DP=30 GT:AD:DP:RGQ ./.:0:0:0 chr1 12356 . G . . . AN=52;DP=30 GT:AD:DP:RGQ ./.:0:0:0 chr1 12357 . G . . . AN=52;DP=30 GT:AD:DP:RGQ ./.:0:0:0 chr1 12358 . C . . . AN=52;DP=30 GT:AD:DP:RGQ ./.:0:0:0 chr1 12359 . T . . . AN=52;DP=31 GT:AD:DP:RGQ ./.:0:0:0 chr1 12360 . G . . . AN=54;DP=31 GT:AD:DP:RGQ ./.:0:0:0 chr1 12361 . G . . . AN=58;DP=33 GT:AD:DP:RGQ ./.:0:0:0 chr1 12362 . A . . . AN=58;DP=32 GT:AD:DP:RGQ ./.:0:0:0 chr1 12363 . G . . . AN=58;DP=32 GT:AD:DP:RGQ ./.:0:0:0 chr1 12364 . G . . . AN=60;DP=33 GT:AD:DP:RGQ ./.:0:0:0 chr1 12365 . G . . . AN=60;DP=32 GT:AD:DP:RGQ ./.:0:0:0 chr1 12366 . A . . . AN=56;DP=33 GT:AD:DP:RGQ ./.:0:0:0 chr1 12367 . G . . . AN=62;DP=33 GT:AD:DP:RGQ ./.:0:0:0 chr1 12368 . G . . . AN=62;DP=33 GT:AD:DP:RGQ ./.:0:0:0 chr1 12369 . G . . . AN=62;DP=33 GT:AD:DP:RGQ ./.:0:0:0 chr1 12370 . G . . . AN=64;DP=34 GT:AD:DP:RGQ ./.:0:0:0 chr1 12371 . C . . . AN=66;DP=36 GT:AD:DP:RGQ ./.:0:0:0 chr1 12372 . T . . . AN=64;DP=37 GT:AD:DP:RGQ ./.:0:0:0 chr1 12373 . C . . . AN=68;DP=37 GT:AD:DP:RGQ ./.:0:0:0 chr1 12374 . A . . . AN=66;DP=38 GT:AD:DP:RGQ ./.:0:0:0 chr1 12375 . G . . . AN=72;DP=39 GT:AD:DP:RGQ ./.:0:0:0 chr1 12376 . C . . . AN=74;DP=40 GT:AD:DP:RGQ ./.:0:0:0 chr1 12377 . A . . . AN=76;DP=43 GT:AD:DP:RGQ ./.:0:0:0 chr1 12378 . G . . . AN=78;DP=43 GT:AD:DP:RGQ ./.:0:0:0 chr1 12379 . G . . . AN=78;DP=43 GT:AD:DP:RGQ ./.:0:0:0 chr1 12380 . T . . . AN=76;DP=44 GT:AD:DP:RGQ ./.:0:0:0 chr1 12381 . C . . . AN=80;DP=44 GT:AD:DP:RGQ ./.:0:0:0 chr1 12382 . T . . . AN=78;DP=44 GT:AD:DP:RGQ ./.:0:0:0 chr1 12383 . G . . . AN=76;DP=44 GT:AD:DP:RGQ ./.:0:0:0 chr1 12384 . G . . . AN=80;DP=44 GT:AD:DP:RGQ ./.:0:0:0 chr1 12385 . C . . . AN=82;DP=45 GT:AD:DP:RGQ ./.:0:0:0 chr1 12386 . T . . . AN=76;DP=45 GT:AD:DP:RGQ ./.:0:0:0 chr1 12387 . T . . . AN=82;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12388 . T . . . AN=84;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12389 . G . . . AN=84;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12390 . G . . . AN=84;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12391 . C . . . AN=84;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12392 . C . . . AN=84;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12393 . C . . . AN=82;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12394 . T . . . AN=78;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12395 . G . . . AN=84;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12396 . G . . . AN=82;DP=46 GT:AD:DP:RGQ ./.:0:0:0 chr1 12397 . G . . . AN=86;DP=47 GT:AD:DP:RGQ ./.:0:0:0 chr1 12398 . A . . . AN=72;DP=47 GT:AD:DP:RGQ ./.:0:0:0 chr1 12399 . G . . . AN=88;DP=48 GT:AD:DP:RGQ ./.:0:0:0 chr1 12400 . A . . . AN=76;DP=48 GT:AD:DP:RGQ ./.:0:0:0 chr1 12401 . G . . . AN=88;DP=49 GT:AD:DP:RGQ ./.:0:0:0 chr1 12402 . C . . . AN=90;DP=49 GT:AD:DP:RGQ ./.:0:0:0 chr1 12403 . A . . . AN=86;DP=49 GT:AD:DP:RGQ ./.:0:0:0 chr1 12404 . G . . . AN=88;DP=49 GT:AD:DP:RGQ ./.:0:0:0 chr1 12405 . G . . . AN=88;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12406 . T . . . AN=72;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12407 . G . . . AN=86;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12408 . G . . . AN=84;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12409 . A . . . AN=72;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12410 . A . . . AN=74;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12411 . G . . . AN=84;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12412 . A . . . AN=76;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12413 . T . . . AN=72;DP=50 GT:AD:DP:RGQ ./.:0:0:0 chr1 12414 . C . . . AN=84;DP=51 GT:AD:DP:RGQ ./.:0:0:0 chr1 12415 . A . . . AN=86;DP=52 GT:AD:DP:RGQ ./.:0:0:0 chr1 12416 . G . . . AN=88;DP=53 GT:AD:DP:RGQ ./.:0:0:0 chr1 12417 . G . . . AN=90;DP=53 GT:AD:DP:RGQ ./.:0:0:0 chr1 12418 . C . . . AN=88;DP=53 GT:AD:DP:RGQ ./.:0:0:0 chr1 12419 . A . . . AN=88;DP=54 GT:AD:DP:RGQ ./.:0:0:0 chr1 12420 . G . . . AN=92;DP=55 GT:AD:DP:RGQ ./.:0:0:0 chr1 12421 . G . . . AN=94;DP=56 GT:AD:DP:RGQ ./.:0:0:0 chr1 12422 . C . . . AN=96;DP=57 GT:AD:DP:RGQ ./.:0:0:0 chr1 12423 . C . . . AN=98;DP=58 GT:AD:DP:RGQ ./.:0:0:0 chr1 12424 . A . . . AN=98;DP=61 GT:AD:DP:RGQ ./.:0:0:0 chr1 12425 . T . . . AN=94;DP=62 GT:AD:DP:RGQ ./.:0:0:0 chr1 12426 . C . . . AN=100;DP=62 GT:AD:DP:RGQ ./.:0:0:0 chr1 12427 . G . . . AN=102;DP=63 GT:AD:DP:RGQ ./.:0:0:0 chr1 12428 . C . . . AN=102;DP=63 GT:AD:DP:RGQ ./.:0:0:0 chr1 12429 . T . . . AN=102;DP=64 GT:AD:DP:RGQ ./.:0:0:0 chr1 12430 . G . . . AN=102;DP=64 GT:AD:DP:RGQ ./.:0:0:0 chr1 12431 . C . . . AN=106;DP=65 GT:AD:DP:RGQ ./.:0:0:0 chr1 12432 . C . . . AN=110;DP=67 GT:AD:DP:RGQ ./.:0:0:0 chr1 12433 . A . . . AN=108;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 12434 . C . . . AN=112;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 12435 . A . . . AN=112;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 12436 . G . . . AN=112;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 12437 . A . . . AN=108;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 12438 . A . . . AN=110;DP=68 GT:AD:DP:RGQ ./.:0:0:0 chr1 12439 . C . . . AN=114;DP=70 GT:AD:DP:RGQ ./.:0:0:0 chr1 12440 . C . . . AN=114;DP=70 GT:AD:DP:RGQ ./.:0:0:0 chr1 12441 . C . . . AN=114;DP=71 GT:AD:DP:RGQ ./.:0:0:0 chr1 12442 . A . . . AN=108;DP=71 GT:AD:DP:RGQ ./.:0:0:0 chr1 12443 . G . . . AN=116;DP=72 GT:AD:DP:RGQ ./.:0:0:0 chr1 12444 . T . . . AN=104;DP=72 GT:AD:DP:RGQ ./.:0:0:0 chr1 12445 . G . . . AN=114;DP=73 GT:AD:DP:RGQ ./.:0:0:0 chr1 12446 . G . . . AN=116;DP=73 GT:AD:DP:RGQ ./.:0:0:0 chr1 12447 . A . . . AN=116;DP=73 GT:AD:DP:RGQ ./.:0:0:0 chr1 12448 . T . . . AN=114;DP=74 GT:AD:DP:RGQ ./.:0:0:0 chr1 12449 . T . . . AN=118;DP=74 GT:AD:DP:RGQ ./.:0:0:0 chr1 12450 . G . . . AN=118;DP=75 GT:AD:DP:RGQ ./.:0:0:0 chr1 12451 . G . . . AN=122;DP=75 GT:AD:DP:RGQ ./.:0:0:0 chr1 12452 . C . . . AN=120;DP=75 GT:AD:DP:RGQ ./.:0:0:0 chr1 12453 . C . . . AN=124;DP=75 GT:AD:DP:RGQ ./.:0:0:0 chr1 12454 . T . . . AN=124;DP=76 GT:AD:DP:RGQ ./.:0:0:0 chr1 12455 . A . . . AN=120;DP=75 GT:AD:DP:RGQ ./.:0:0:0 chr1 12456 . G . . . AN=128;DP=76 GT:AD:DP:RGQ ./.:0:0:0 chr1 12457 . G . . . AN=126;DP=78 GT:AD:DP:RGQ ./.:0:0:0 chr1 12458 . T . . . AN=126;DP=79 GT:AD:DP:RGQ ./.:0:0:0 chr1 12459 . G . . . AN=134;DP=79 GT:AD:DP:RGQ ./.:0:0:0 chr1 12460 . G . . . AN=136;DP=81 GT:AD:DP:RGQ ./.:0:0:0 chr1 12461 . G . . . AN=140;DP=83 GT:AD:DP:RGQ ./.:0:0:0 chr1 12462 . A . . . AN=134;DP=84 GT:AD:DP:RGQ ./.:0:0:0 chr1 12463 . T . . . AN=140;DP=84 GT:AD:DP:RGQ ./.:0:0:0 chr1 12464 . C . . . AN=144;DP=85 GT:AD:DP:RGQ ./.:0:0:0 chr1 12465 . T . . . AN=136;DP=85 GT:AD:DP:RGQ ./.:0:0:0 chr1 12466 . C . . . AN=148;DP=87 GT:AD:DP:RGQ ./.:0:0:0 chr1 12467 . T . . . AN=148;DP=88 GT:AD:DP:RGQ ./.:0:0:0 chr1 12468 . G . . . AN=142;DP=87 GT:AD:DP:RGQ ./.:0:0:0 chr1 12469 . A . . . AN=148;DP=89 GT:AD:DP:RGQ ./.:0:0:0 chr1 12470 . G . . . AN=146;DP=90 GT:AD:DP:RGQ ./.:0:0:0 chr1 12471 . C . . . AN=150;DP=91 GT:AD:DP:RGQ ./.:0:0:0 chr1 12472 . T . . . AN=142;DP=90 GT:AD:DP:RGQ ./.:0:0:0 chr1 12473 . C . . . AN=150;DP=91 GT:AD:DP:RGQ ./.:0:0:0 chr1 12474 . A . . . AN=152;DP=92 GT:AD:DP:RGQ ./.:0:0:0 chr1 12475 . A . . . AN=152;DP=92 GT:AD:DP:RGQ ./.:0:0:0 chr1 12476 . C . . . AN=156;DP=93 GT:AD:DP:RGQ ./.:0:0:0 chr1 12477 . A . . . AN=156;DP=93 GT:AD:DP:RGQ ./.:0:0:0 chr1 12478 . A . . . AN=154;DP=94 GT:AD:DP:RGQ ./.:0:0:0 chr1 12479 . G . . . AN=162;DP=95 GT:AD:DP:RGQ ./.:0:0:0 chr1 12480 . C . . . AN=160;DP=94 GT:AD:DP:RGQ ./.:0:0:0 chr1 12481 . C . . . AN=166;DP=95 GT:AD:DP:RGQ ./.:0:0:0 chr1 12482 . C . . . AN=166;DP=98 GT:AD:DP:RGQ ./.:0:0:0 chr1 12483 . T . . . AN=172;DP=101 GT:AD:DP:RGQ ./.:0:0:0 chr1 12484 . C . . . AN=178;DP=105 GT:AD:DP:RGQ ./.:0:0:0 chr1 12485 . T . . . AN=174;DP=108 GT:AD:DP:RGQ ./.:0:0:0 chr1 12486 . C . . . AN=190;DP=113 GT:AD:DP:RGQ ./.:0:0:0 chr1 12487 . T . . . AN=186;DP=114 GT:AD:DP:RGQ ./.:0:0:0 chr1 12488 . G . . . AN=192;DP=114 GT:AD:DP:RGQ ./.:0:0:0 chr1 12489 . G . . . AN=196;DP=119 GT:AD:DP:RGQ ./.:0:0:0 chr1 12490 . G . . . AN=202;DP=122 GT:AD:DP:RGQ ./.:0:0:0 chr1 12491 . T . . . AN=188;DP=122 GT:AD:DP:RGQ ./.:0:0:0 chr1 12492 . G . . . AN=208;DP=125 GT:AD:DP:RGQ ./.:0:0:0 chr1 12493 . G . . . AN=212;DP=127 GT:AD:DP:RGQ ./.:0:0:0 chr1 12494 . T . . . AN=192;DP=125 GT:AD:DP:RGQ ./.:0:0:0 chr1 12495 . A . . . AN=204;DP=126 GT:AD:DP:RGQ ./.:0:0:0 chr1 12496 . G . . . AN=212;DP=128 GT:AD:DP:RGQ ./.:0:0:0 chr1 12497 . G . . . AN=218;DP=131 GT:AD:DP:RGQ ./.:0:0:0 chr1 12498 . T . . . AN=218;DP=133 GT:AD:DP:RGQ ./.:0:0:0 chr1 12499 . G . . . AN=218;DP=134 GT:AD:DP:RGQ ./.:0:0:0 chr1 12500 . C . . . AN=224;DP=136 GT:AD:DP:RGQ ./.:0:0:0 chr1 12501 . A . . . AN=224;DP=139 GT:AD:DP:RGQ ./.:0:0:0 chr1 12502 . G . . . AN=236;DP=142 GT:AD:DP:RGQ ./.:0:0:0 chr1 12503 . A . . . AN=234;DP=144 GT:AD:DP:RGQ ./.:0:0:0 chr1 12504 . G . . . AN=240;DP=146 GT:AD:DP:RGQ ./.:0:0:0 chr1 12505 . A . . . AN=240;DP=148 GT:AD:DP:RGQ ./.:0:0:0 chr1 12506 . C . . . AN=246;DP=150 GT:AD:DP:RGQ ./.:0:0:0 chr1 12507 . G . . . AN=258;DP=157 GT:AD:DP:RGQ ./.:0:0:0 chr1 12508 . G . . . AN=264;DP=159 GT:AD:DP:RGQ ./.:0:0:0 chr1 12509 . G . . . AN=270;DP=163 GT:AD:DP:RGQ ./.:0:0:0 chr1 12510 . A . . . AN=264;DP=164 GT:AD:DP:RGQ ./.:0:0:0 chr1 12511 . G . . . AN=274;DP=167 GT:AD:DP:RGQ ./.:0:0:0 chr1 12512 . G . . . AN=278;DP=171 GT:AD:DP:RGQ ./.:0:0:0 chr1 12513 . G . . . AN=274;DP=171 GT:AD:DP:RGQ ./.:0:0:0 chr1 12514 . G . . . AN=280;DP=176 GT:AD:DP:RGQ ./.:0:0:0 chr1 12515 . C . . . AN=280;DP=178 GT:AD:DP:RGQ ./.:0:0:0 chr1 12516 . A . . . AN=284;DP=181 GT:AD:DP:RGQ ./.:0:0:0 chr1 12517 . G . . . AN=292;DP=185 GT:AD:DP:RGQ ./.:0:0:0 chr1 12518 . A . . . AN=302;DP=191 GT:AD:DP:RGQ ./.:0:0:0 chr1 12519 . G . . . AN=308;DP=195 GT:AD:DP:RGQ ./.:0:0:0 chr1 12520 . C . . . AN=312;DP=200 GT:AD:DP:RGQ ./.:0:0:0 chr1 12521 . C . . . AN=314;DP=204 GT:AD:DP:RGQ ./.:0:0:0 chr1 12522 . G . . . AN=326;DP=212 GT:AD:DP:RGQ ./.:0:0:0 chr1 12523 . C . . . AN=344;DP=220 GT:AD:DP:RGQ ./.:0:0:0 chr1 12524 . A . . . AN=342;DP=222 GT:AD:DP:RGQ ./.:0:0:0 chr1 12525 . G . . . AN=354;DP=226 GT:AD:DP:RGQ ./.:0:0:0 chr1 12526 . G . . . AN=352;DP=225 GT:AD:DP:RGQ ./.:0:0:0 chr1 12527 . C . . . AN=360;DP=230 GT:AD:DP:RGQ ./.:0:0:0 chr1 12528 . A . . . AN=352;DP=233 GT:AD:DP:RGQ ./.:0:0:0 chr1 12529 . C . . . AN=374;DP=237 GT:AD:DP:RGQ ./.:0:0:0 chr1 12530 . A . . . AN=372;DP=243 GT:AD:DP:RGQ ./.:0:0:0 chr1 12531 . G . . . AN=384;DP=250 GT:AD:DP:RGQ ./.:0:0:0 chr1 12532 . C . . . AN=388;DP=255 GT:AD:DP:RGQ ./.:0:0:0 chr1 12533 . C . . . AN=390;DP=261 GT:AD:DP:RGQ ./.:0:0:0 chr1 12534 . A . . . AN=396;DP=268 GT:AD:DP:RGQ ./.:0:0:0 chr1 12535 . A . . . AN=400;DP=271 GT:AD:DP:RGQ ./.:0:0:0 chr1 12536 . G . . . AN=420;DP=278 GT:AD:DP:RGQ ./.:0:0:0 chr1 12537 . A . . . AN=422;DP=281 GT:AD:DP:RGQ ./.:0:0:0 chr1 12538 . G . . . AN=428;DP=282 GT:AD:DP:RGQ ./.:0:0:0 chr1 12539 . G . . . AN=434;DP=286 GT:AD:DP:RGQ ./.:0:0:0 chr1 12540 . G . . . AN=426;DP=288 GT:AD:DP:RGQ ./.:0:0:0 chr1 12541 . C . . . AN=436;DP=295 GT:AD:DP:RGQ ./.:0:0:0 chr1 12542 . T . . . AN=432;DP=303 GT:AD:DP:RGQ ./.:0:0:0 chr1 12543 . G . . . AN=460;DP=310 GT:AD:DP:RGQ ./.:0:0:0 chr1 12544 . A . . . AN=466;DP=322 GT:AD:DP:RGQ ./.:0:0:0 chr1 12545 . A C . . AC=0;AF=0;AN=470;DP=325;ExcessHet=3.01;MQ=1.11 GT:AD:DP:PGT:PID:RGQ ./.:0,0:0:.:.:0 chr1 12546 . G . . . AN=480;DP=330 GT:AD:DP:RGQ ./.:0:0:0 chr1 12547 . A C . . AC=0;AF=0;AN=490;DP=337;ExcessHet=3.01;MQ=1.09 GT:AD:DP:PGT:PID:RGQ ./.:0,0:0:.:.:0 chr1 12548 . A . . . AN=496;DP=344 GT:AD:DP:RGQ ./.:0:0:0 chr1 12549 . A . . . AN=500;DP=353 GT:AD:DP:RGQ ./.:0:0:0 chr1 12550 . T . . . AN=490;DP=354 GT:AD:DP:RGQ ./.:0:0:0 chr1 12551 . G . . . AN=510;DP=356 GT:AD:DP:RGQ ./.:0:0:0 chr1 12552 . G . . . AN=516;DP=363 GT:AD:DP:RGQ ./.:0:0:0 chr1 12553 . T . . . AN=510;DP=370 GT:AD:DP:RGQ ./.:0:0:0 chr1 12554 . A . . . AN=514;DP=373 GT:AD:DP:RGQ ./.:0:0:0 chr1 12555 . G . . . AN=526;DP=376 GT:AD:DP:RGQ ./.:0:0:0 chr1 12556 . A . . . AN=536;DP=382 GT:AD:DP:RGQ ./.:0:0:0 chr1 12557 . A . . . AN=538;DP=387 GT:AD:DP:RGQ ./.:0:0:0 chr1 12558 . C . . . AN=546;DP=396 GT:AD:DP:RGQ ./.:0:0:0 chr1 12559 . G . . . AN=560;DP=406 GT:AD:DP:RGQ ./.:0:0:0 chr1 12560 . G . . . AN=572;DP=418 GT:AD:DP:RGQ ./.:0:0:0 chr1 12561 . A . . . AN=560;DP=430 GT:AD:DP:RGQ ./.:0:0:0 chr1 12562 . G . . . AN=588;DP=438 GT:AD:DP:RGQ ./.:0:0:0 chr1 12563 . C . . . AN=598;DP=448 GT:AD:DP:RGQ ./.:0:0:0 chr1 12564 . A . . . AN=586;DP=457 GT:AD:DP:RGQ ./.:0:0:0 chr1 12565 . G . . . AN=612;DP=465 GT:AD:DP:RGQ ./.:0:0:0 chr1 12566 . C . . . AN=616;DP=472 GT:AD:DP:RGQ ./.:0:0:0 chr1 12567 . T . . . AN=608;DP=485 GT:AD:DP:RGQ ./.:0:0:0 chr1 12568 . G . . . AN=628;DP=492 GT:AD:DP:RGQ ./.:0:0:0 chr1 12569 . G . . . AN=636;DP=500 GT:AD:DP:RGQ ./.:0:0:0 chr1 12570 . T . . . AN=618;DP=504 GT:AD:DP:RGQ ./.:0:0:0 chr1 12571 . G . . . AN=644;DP=511 GT:AD:DP:RGQ ./.:0:0:0 chr1 12572 . A . . . AN=626;DP=517 GT:AD:DP:RGQ ./.:0:0:0 chr1 12573 . T . . . AN=622;DP=520 GT:AD:DP:RGQ ./.:0:0:0 chr1 12574 . G . . . AN=648;DP=526 GT:AD:DP:RGQ ./.:0:0:0 chr1 12575 . T . . . AN=640;DP=533 GT:AD:DP:RGQ ./.:0:0:0 chr1 12576 . G . . . AN=666;DP=536 GT:AD:DP:RGQ ./.:0:0:0 chr1 12577 . T . . . AN=668;DP=545 GT:AD:DP:RGQ ./.:0:0:0 chr1 12578 . G . . . AN=676;DP=546 GT:AD:DP:RGQ ./.:0:0:0 chr1 12579 . G . . . AN=676;DP=552 GT:AD:DP:RGQ ./.:0:0:0 chr1 12580 . G . . . AN=692;DP=559 GT:AD:DP:RGQ ./.:0:0:0 chr1 12581 . C . . . AN=690;DP=567 GT:AD:DP:RGQ ./.:0:0:0 chr1 12582 . C . . . AN=700;DP=575 GT:AD:DP:RGQ ./.:0:0:0 chr1 12583 . C . . . AN=716;DP=584 GT:AD:DP:RGQ ./.:0:0:0 chr1 12584 . A . . . AN=714;DP=594 GT:AD:DP:RGQ ./.:0:0:0 chr1 12585 . C . . . AN=722;DP=603 GT:AD:DP:RGQ ./.:0:0:0 chr1 12586 . C . . . AN=734;DP=609 GT:AD:DP:RGQ ./.:0:0:0 chr1 12587 . G . . . AN=746;DP=632 GT:AD:DP:RGQ ./.:0:0:0 chr1 12588 . G . . . AN=756;DP=644 GT:AD:DP:RGQ ./.:0:0:0 chr1 12589 . C . . . AN=758;DP=655 GT:AD:DP:RGQ ./.:0:0:0 chr1 12590 . C . . . AN=756;DP=661 GT:AD:DP:RGQ ./.:0:0:0 chr1 12591 . C . . . AN=758;DP=672 GT:AD:DP:RGQ ./.:0:0:0 chr1 12592 . C . . . AN=768;DP=679 GT:AD:DP:RGQ ./.:0:0:0 chr1 12593 . A . . . AN=760;DP=687 GT:AD:DP:RGQ ./.:0:0:0 chr1 12594 . G . . . AN=780;DP=694 GT:AD:DP:RGQ ./.:0:0:0 chr1 12595 . G . . . AN=776;DP=706 GT:AD:DP:RGQ ./.:0:0:0 bcftools-1.21/test/head.1.out000066400000000000000000000000761467060157400160350ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 bcftools-1.21/test/head.2.out000066400000000000000000000004171467060157400160350ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 chr1 212740 . A G,<*> 0 . DP=73;I16=0,0,39,4,0,0,2743,192525,0,0,2580,154800,0,0,825,18621;QS=0,2,0;VDB=0.520868;SGB=-1.38232;MQSB=1;MQ0F=0 PL:DP:AD 255,72,0,255,72,255:24:0,24,0 255,57,0,255,57,255:19:0,19,0 bcftools-1.21/test/head.3.out000066400000000000000000000007631467060157400160420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 chr1 212740 . A G,<*> 0 . DP=73;I16=0,0,39,4,0,0,2743,192525,0,0,2580,154800,0,0,825,18621;QS=0,2,0;VDB=0.520868;SGB=-1.38232;MQSB=1;MQ0F=0 PL:DP:AD 255,72,0,255,72,255:24:0,24,0 255,57,0,255,57,255:19:0,19,0 chr1 320055 . A <*> 0 . DP=101;I16=52,9,0,0,4116,300666,0,0,3660,219600,0,0,1281,29849,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:AD 0,87,255:29:29,0 0,96,255:32:32,0 bcftools-1.21/test/idx.1.out000066400000000000000000000001241467060157400157120ustar00rootroot000000000000001 9 rs1_9_GGG_G GGG G . . . 1 10 rs1_10_GGG_T GGG T . . . 1 10 rs1_10_G_T G T . . . bcftools-1.21/test/idx.1.vcf000066400000000000000000000004001467060157400156560ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO 1 9 rs1_9_GGG_G GGG G . . . 1 9 rs1_9_G_T G T . . . 1 10 rs1_10_GGG_T GGG T . . . 1 10 rs1_10_G_T G T . . . 1 15 rs1_15_G_T G T . . . bcftools-1.21/test/idx.2.bed000066400000000000000000000000441467060157400156370ustar00rootroot000000000000001 1172777 1172804 1 1172806 1172808 bcftools-1.21/test/idx.2.out000066400000000000000000000001061467060157400157130ustar00rootroot000000000000001 1172783 . CCTCTGTCCTGGTCGCGTTGCCCAGCG C . . . 1 1172784 . C T . . . bcftools-1.21/test/idx.2.vcf000066400000000000000000000002021467060157400156570ustar00rootroot00000000000000##fileformat=VCFv4.1 #CHROM POS ID REF ALT QUAL FILTER INFO 1 1172783 . CCTCTGTCCTGGTCGCGTTGCCCAGCG C . . . 1 1172784 . C T . . . bcftools-1.21/test/idx.3.bed000066400000000000000000000001501467060157400156360ustar00rootroot00000000000000‹ÿBCK=̱ CÁZ¦” û/fa º¼_Äb‡Ç¡)Æu¿Ð.hc huI¥>eÓyN>—ÊUPOÀ~‹ÿBCbcftools-1.21/test/idx.3.out000066400000000000000000000001211467060157400157110ustar00rootroot000000000000001 6535254 . GCCCTCCTCCCCACCCTCCTTCCCACCCTCCTTCCCAA G . . . 1 6535274 . T C . . . bcftools-1.21/test/idx.3.vcf000066400000000000000000000003031467060157400156620ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##reference=hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO 1 6535254 . GCCCTCCTCCCCACCCTCCTTCCCACCCTCCTTCCCAA G . . . 1 6535274 . T C . . . bcftools-1.21/test/idx.4.bed000066400000000000000000000000621467060157400156410ustar00rootroot00000000000000chr1 156134804 156134974 chr1 156135186 156135311 bcftools-1.21/test/idx.4.out000066400000000000000000000000621467060157400157160ustar00rootroot00000000000000chr1 156134692 . C . PASS END=156135413 bcftools-1.21/test/idx.4.vcf000066400000000000000000000005171467060157400156720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##ALT= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 156134692 . C . PASS END=156135413 bcftools-1.21/test/idx.out000066400000000000000000000000701467060157400155530ustar00rootroot0000000000000011 135006516 2 20 63025520 7 X 155270560 4 Y 59373566 2 bcftools-1.21/test/idx.vcf000066400000000000000000000012751467060157400155320ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 11 2343543 . A . 999 PASS . 11 5464562 . C T 999 PASS . 20 76962 . T C 999 PASS . 20 126310 . ACC A 999 PASS . 20 138125 . G T 999 PASS . 20 138148 . C T 999 PASS . 20 271225 . T TTTA,TA 999 PASS . 20 304568 . C T 999 PASS . 20 326891 . A AC 999 PASS . X 2928329 . C T 999 PASS . X 2933066 . G C 999 PASS . X 2942109 . T C 999 PASS . X 3048719 . T C 999 PASS . Y 8657215 . C A 999 PASS . Y 10011673 . G A 999 PASS . bcftools-1.21/test/idx_count.out000066400000000000000000000000031467060157400167570ustar00rootroot0000000000000015 bcftools-1.21/test/indel-stats.1.out000066400000000000000000000046061467060157400173660ustar00rootroot00000000000000# CMD line shows the command line used to generate this output # DEF lines define expressions for all tested thresholds # SN* summary number for every threshold: # 1) SN*, filter id # 2) number of samples (or trios with -p) # 3) number of indel sites total # 4) number of indel sites that pass the filter (and, with -p, have a de novo indel) # 5) number of indel genotypes that pass the filter (and, with -p, are de novo) # 6) number of insertions (site-wise, not genotype-wise) # 7) number of deletions (site-wise, not genotype-wise) # 8) number of frameshifts (site-wise, not genotype-wise) # 9) number of inframe indels (site-wise, not genotype-wise) # # DVAF* lines report indel variant allele frequency (VAF) distribution for every threshold, # k-th bin corresponds to the frequency k/(nVAF-1): # 1) DVAF*, filter id # 2) nVAF, number of bins which split the [0,1] VAF interval. # 3-22) counts of indel genotypes in the VAF bin. For non-reference hets, the VAF of the less supported allele is recorded # # DLEN* lines report indel length distribution for every threshold. When genotype fields are available, # the counts correspond to the number of genotypes, otherwise the number of sites are given. # The k-th bin corresponds to the indel size k-MAX_LEN, negative for deletions, positive for insertions. # The first/last bin contains also all deletions/insertions larger than MAX_LEN: # 1) DLEN*, filter id # 2) maximum indel length # 3-43) counts of indel lengths (-max,..,0,..,max), all unique alleles in a genotype are recorded (alt hets increase the counters 2x, alt homs 1x) # # DFRAC* lines report the mean minor allele fraction at HET indel genotypes as a function of indel size. # The format is the same as for DLEN: # 1) DFRAC*, filter id # 2) maximum indel length # 3-43) mean fraction at indel lengths (-max,..,0,..,max) # # NFRAC* lines report the number of indels informing the DFRAC distribution. # 1) NFRAC*, filter id # 2) maximum indel length # 3-43) counts at indel lengths (-max,..,0,..,max) # DEF FLT0 all SN0 6 3 3 5 2 1 1 1 DVAF0 20 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 1 DLEN0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DFRAC0 20 . . . . . . . . . . . . . . . . . . 0.50 . . 0.50 0.50 . . . . . . . . . . . . . . . . . . NFRAC0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 bcftools-1.21/test/indel-stats.2.out000066400000000000000000000046001467060157400173610ustar00rootroot00000000000000# CMD line shows the command line used to generate this output # DEF lines define expressions for all tested thresholds # SN* summary number for every threshold: # 1) SN*, filter id # 2) number of samples (or trios with -p) # 3) number of indel sites total # 4) number of indel sites that pass the filter (and, with -p, have a de novo indel) # 5) number of indel genotypes that pass the filter (and, with -p, are de novo) # 6) number of insertions (site-wise, not genotype-wise) # 7) number of deletions (site-wise, not genotype-wise) # 8) number of frameshifts (site-wise, not genotype-wise) # 9) number of inframe indels (site-wise, not genotype-wise) # # DVAF* lines report indel variant allele frequency (VAF) distribution for every threshold, # k-th bin corresponds to the frequency k/(nVAF-1): # 1) DVAF*, filter id # 2) nVAF, number of bins which split the [0,1] VAF interval. # 3-22) counts of indel genotypes in the VAF bin. For non-reference hets, the VAF of the less supported allele is recorded # # DLEN* lines report indel length distribution for every threshold. When genotype fields are available, # the counts correspond to the number of genotypes, otherwise the number of sites are given. # The k-th bin corresponds to the indel size k-MAX_LEN, negative for deletions, positive for insertions. # The first/last bin contains also all deletions/insertions larger than MAX_LEN: # 1) DLEN*, filter id # 2) maximum indel length # 3-43) counts of indel lengths (-max,..,0,..,max), all unique alleles in a genotype are recorded (alt hets increase the counters 2x, alt homs 1x) # # DFRAC* lines report the mean minor allele fraction at HET indel genotypes as a function of indel size. # The format is the same as for DLEN: # 1) DFRAC*, filter id # 2) maximum indel length # 3-43) mean fraction at indel lengths (-max,..,0,..,max) # # NFRAC* lines report the number of indels informing the DFRAC distribution. # 1) NFRAC*, filter id # 2) maximum indel length # 3-43) counts at indel lengths (-max,..,0,..,max) # DEF FLT0 all SN0 2 3 2 2 2 0 1 0 DVAF0 20 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 DLEN0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DFRAC0 20 . . . . . . . . . . . . . . . . . . . . . . 0.50 . . . . . . . . . . . . . . . . . . NFRAC0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 bcftools-1.21/test/indel-stats.3.out000066400000000000000000000046001467060157400173620ustar00rootroot00000000000000# CMD line shows the command line used to generate this output # DEF lines define expressions for all tested thresholds # SN* summary number for every threshold: # 1) SN*, filter id # 2) number of samples (or trios with -p) # 3) number of indel sites total # 4) number of indel sites that pass the filter (and, with -p, have a de novo indel) # 5) number of indel genotypes that pass the filter (and, with -p, are de novo) # 6) number of insertions (site-wise, not genotype-wise) # 7) number of deletions (site-wise, not genotype-wise) # 8) number of frameshifts (site-wise, not genotype-wise) # 9) number of inframe indels (site-wise, not genotype-wise) # # DVAF* lines report indel variant allele frequency (VAF) distribution for every threshold, # k-th bin corresponds to the frequency k/(nVAF-1): # 1) DVAF*, filter id # 2) nVAF, number of bins which split the [0,1] VAF interval. # 3-22) counts of indel genotypes in the VAF bin. For non-reference hets, the VAF of the less supported allele is recorded # # DLEN* lines report indel length distribution for every threshold. When genotype fields are available, # the counts correspond to the number of genotypes, otherwise the number of sites are given. # The k-th bin corresponds to the indel size k-MAX_LEN, negative for deletions, positive for insertions. # The first/last bin contains also all deletions/insertions larger than MAX_LEN: # 1) DLEN*, filter id # 2) maximum indel length # 3-43) counts of indel lengths (-max,..,0,..,max), all unique alleles in a genotype are recorded (alt hets increase the counters 2x, alt homs 1x) # # DFRAC* lines report the mean minor allele fraction at HET indel genotypes as a function of indel size. # The format is the same as for DLEN: # 1) DFRAC*, filter id # 2) maximum indel length # 3-43) mean fraction at indel lengths (-max,..,0,..,max) # # NFRAC* lines report the number of indels informing the DFRAC distribution. # 1) NFRAC*, filter id # 2) maximum indel length # 3-43) counts at indel lengths (-max,..,0,..,max) # DEF FLT0 all SN0 1 3 2 2 2 0 1 0 DVAF0 20 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 DLEN0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DFRAC0 20 . . . . . . . . . . . . . . . . . . . . . . 0.50 . . . . . . . . . . . . . . . . . . NFRAC0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 bcftools-1.21/test/indel-stats.vcf000066400000000000000000000016651467060157400172000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT child1 father1 mother1 child2 father2 mother2 20 310 . T A,C . . . GT 1/1 1/1 1/1 1/2 2/1 1/1 20 311 . T TA . . . GT:AD 1/1:0,20 0/0:20,0 0/0:20,0 0/1:10,10 . 0/0:20,0 20 312 . TAA T . . CSQ=inframe_deletion|SAMD11|ENST00000420190|protein_coding|+|74EDG>74D|865683AGGATGG>A GT:AD 0/1:10,10 1/0:10,10 0/0:20,0 0/0:20,0 0/0:20,0 0/0:20,0 20 313 . A ATT . . CSQ=frameshift|SAMD11|ENST00000342066|protein_coding|+|333LPPAQA GT:AD 0/1:10,10 0/0:10,10 0/0:20,0 0/0:20,0 0/0:20,0 0/0:20,0 bcftools-1.21/test/isec-miss.1.1.out000066400000000000000000000000541467060157400171630ustar00rootroot0000000000000020 100 G T 011 20 140 G A 011 12 55 C T 001 bcftools-1.21/test/isec-miss.1.1.vcf000066400000000000000000000002341467060157400171320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO bcftools-1.21/test/isec-miss.1.2.vcf000066400000000000000000000003021467060157400171270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO 20 100 . G T . . . 20 140 . G A . . . bcftools-1.21/test/isec-miss.1.3.vcf000066400000000000000000000003241467060157400171340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO 20 100 . G T . . . 20 140 . G A . . . 12 55 . C T . . . bcftools-1.21/test/isec-miss.1.regs.txt000066400000000000000000000000371467060157400177740ustar00rootroot0000000000000020 100 100 20 140 140 12 55 55 bcftools-1.21/test/isec-miss.2.1.out000066400000000000000000000002631467060157400171660ustar00rootroot0000000000000020 100 GGAGGAAGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA *,AGAGGAAGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA,GGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA 011 20 140 G A,* 011 12 55 C T 001 bcftools-1.21/test/isec-miss.2.1.vcf000066400000000000000000000002341467060157400171330ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO bcftools-1.21/test/isec-miss.2.2.vcf000066400000000000000000000005111467060157400171320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO 20 100 . GGAGGAAGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA *,AGAGGAAGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA,GGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA . . . 20 140 . G A,* . . . bcftools-1.21/test/isec-miss.2.3.vcf000066400000000000000000000006271467060157400171430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##reference=file://hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT DDD_MAIN6144833 DDD_MAIN6121293 DDD_MAIN6104074 20 100 . GGAGGAAGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA *,AGAGGAAGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA,GGAGGAAGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA . . . 20 140 . G A,* . . . 12 55 . C T 483.62 . . bcftools-1.21/test/isec.a.vcf000066400000000000000000000035111467060157400161030ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3062915 . GTTT G 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 3062915 . G T 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 3106154 . CAAA C 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 1 3106154 . C T,CT 1792 PASS DP=32;AN=2;AC=1,0 GT:GQ:DP 0/1:245:32 1 3157410 . GA G 628 q10 DP=21;AN=2;AC=2 GT:GQ:DP 1/1:21:21 1 3162006 . GAA G 1016 PASS DP=22;AN=2;AC=1 GT:GQ:DP 0/1:212:22 1 3177144 . GT G 727 PASS DP=30;AN=2;AC=1 GT:GQ:DP 0/1:150:30 1 3184885 . TAAAA TA,T 246 PASS DP=10;AN=2;AC=1,1 GT:GQ:DP 1/2:12:10 2 3199812 . G GTT,GT 481 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:322:26 3 3212016 . CTT C,CT 565 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:91:26 4 3212016 . TACACACAC T 325 PASS DP=31;AN=2;AC=1 GT:GQ:DP 0/1:325:31 4 3258448 . TACACACAC T 325 PASS DP=31;AN=2;AC=1 GT:GQ:DP 0/1:325:31 bcftools-1.21/test/isec.ab.C.out000066400000000000000000000001051467060157400164530ustar00rootroot000000000000002 3199812 G GTT,GT 10 3 3212016 CTT C,CT 10 4 3258448 TACACACAC T 10 bcftools-1.21/test/isec.ab.any.out000066400000000000000000000002651467060157400170670ustar00rootroot000000000000001 3062915 GTTT G 11 1 3062915 G T 11 1 3106154 CAAA C 11 1 3106154 C T,CT 11 1 3157410 GA G 11 1 3162006 GAA G 11 1 3177144 GT G 11 1 3184885 TAAAA TA,T 11 4 3212016 TACACACAC T 11 bcftools-1.21/test/isec.ab.both.out000066400000000000000000000002651467060157400172340ustar00rootroot000000000000001 3062915 GTTT G 11 1 3062915 G T 11 1 3106154 CAAA C 11 1 3106154 C T,CT 11 1 3157410 GA G 11 1 3162006 GAA G 11 1 3177144 GT G 11 1 3184885 TAAAA TA,T 11 4 3212016 TACACACAC T 11 bcftools-1.21/test/isec.ab.flt.out000066400000000000000000000000441467060157400170600ustar00rootroot000000000000001 3157410 GA G 11 1 3177144 GT G 11 bcftools-1.21/test/isec.ab.out000066400000000000000000000000671467060157400163010ustar00rootroot000000000000001 3157410 GA G 11 1 3162006 GAA G 11 1 3177144 GT G 11 bcftools-1.21/test/isec.b.vcf000066400000000000000000000034051467060157400161060ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B 1 3062915 . G A 376 q20 DP=14;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:376:14:-10,0,-10 1 3062915 . GTTT GT 376 q20 DP=14;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:376:14:-10,0,-10 1 3106154 . C T 677 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL 0/1:277:15:-10,0,-10 1 3106154 . CAAAA C 677 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL 0/1:277:15:-10,0,-10 1 3157410 . GA G 249 PASS DP=11;AN=2;AC=1 GT:GQ:DP 0/1:49:11 1 3162006 . GAA G 663 PASS DP=19;AN=2;AC=1 GT:GQ:DP 0/1:589:19 1 3177144 . GT G 460 PASS DP=24;AN=2;AC=1 GT:GQ:DP 0/1:236:24 1 3184885 . TAAA T 598 PASS DP=16;AN=2;AC=1 GT:GQ:DP 0/1:435:16 2 3188209 . GA G 162 . DP=15;AN=2;AC=1 GT:GQ:DP 0/1:162:15 3 3199812 . G GTT,GT 353 PASS DP=19;AN=2;AC=1,1 GT:GQ:DP 1/2:188:19 4 3212016 . CTT C 677 q20 DP=15;AN=2;AC=1 GT:GQ:DP 0/1:158:15 bcftools-1.21/test/isec.tab000066400000000000000000000001321467060157400156500ustar00rootroot000000000000001 3062915 3062915 1 3106154 3106154 1 3157410 3162006 1 3177144 3177144 4 3212016 3212016 bcftools-1.21/test/isec.tab.out000066400000000000000000000031541467060157400164650ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##readme=AAAAAA ##readme=BBBBBB #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3062915 . GTTT G 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 3062915 . G T 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 3106154 . CAAA C 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 1 3106154 . C T,CT 1792 PASS DP=32;AN=2;AC=1,0 GT:GQ:DP 0/1:245:32 1 3157410 . GA G 628 q10 DP=21;AN=2;AC=2 GT:GQ:DP 1/1:21:21 1 3162006 . GAA G 1016 PASS DP=22;AN=2;AC=1 GT:GQ:DP 0/1:212:22 1 3177144 . GT G 727 PASS DP=30;AN=2;AC=1 GT:GQ:DP 0/1:150:30 4 3212016 . TACACACAC T 325 PASS DP=31;AN=2;AC=1 GT:GQ:DP 0/1:325:31 bcftools-1.21/test/large_chrom.20.1.2147483647.out000066400000000000000000000004401467060157400207250ustar00rootroot00000000000000chr20 76962 . T C 999 PASS . chr20 126310 . ACC A 999 PASS . chr20 138125 . G T 999 PASS . chr20 138148 . C T 999 PASS . chr20 271225 . T TTTA,TA 999 PASS . chr20 304568 . C T 999 PASS . chr20 620255100 . AG T 999 PASS . chr20 630255200 . G C 999 PASS . chr20 2147483647 . A T 999 PASS . bcftools-1.21/test/large_chrom_csi_limit.20.1.2147483647.out000066400000000000000000000004401467060157400227610ustar00rootroot00000000000000chr20 76962 . T C 999 PASS . chr20 126310 . ACC A 999 PASS . chr20 138125 . G T 999 PASS . chr20 138148 . C T 999 PASS . chr20 271225 . T TTTA,TA 999 PASS . chr20 304568 . C T 999 PASS . chr20 620255100 . AG T 999 PASS . chr20 630255200 . G C 999 PASS . chr20 2147483647 . A T 999 PASS . bcftools-1.21/test/large_chrom_csi_limit.vcf000066400000000000000000000011561467060157400212620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///seq/references/long_chrom.fasta ##FILTER= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr11 2343543 . A . 999 PASS . chr11 5464562 . C T 999 PASS . chr11 116870911 . C G 999 PASS . chr20 76962 . T C 999 PASS . chr20 126310 . ACC A 999 PASS . chr20 138125 . G T 999 PASS . chr20 138148 . C T 999 PASS . chr20 271225 . T TTTA,TA 999 PASS . chr20 304568 . C T 999 PASS . chr20 620255100 . AG T 999 PASS . chr20 630255200 . G C 999 PASS . chr20 2147483647 . A T 999 PASS . bcftools-1.21/test/many-alts.vcf000066400000000000000000000016231467060157400166500ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A C,AA,AAA,AAAA,AAAAA,AAAAAA,AAAAAAA,AAAAAAAA,AAAAAAAAA,AAAAAAAAAA,AAAAAAAAAAA,AAAAAAAAAAAA,AAAAAAAAAAAAA,AAAAAAAAAAAAAA,AAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 999 . . GT 0/1 2/3 33/34 bcftools-1.21/test/many.alleles.trim.out000066400000000000000000000012141467060157400203260ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##contig= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SRR1528791 chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCG . . AC=2;AN=2 GT 1/1 chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCG . . AC=2;AN=2 GT 1/1 chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCG . . AC=2;AN=2 GT 1/1 bcftools-1.21/test/many.alleles.vcf000066400000000000000000000046041467060157400173310ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///some/path/1000GenomesPilot-NCBI36.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SRR1528791 chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCC,CCATCTCTCTCCCCG,CCTTCTCTCTGCCCC,CCCTCTCTCTCCCCC,CCACCTCTCTGCCCC,CCACCCCTCTGCCCA,CCACCTCCCTCCCCC,CCACCTCCCTGCCCA,CCACCTCTCGGCCCC,CCACCTCTCGGCCCA,CCACCTCTCTCCCCC,CCACCTCTCTCCCCA,CCATCCCCCTCCCCC,CCATCCCCCTGCCCC,CCATCCCCCTGCCCA,CCATCCCTCGGCCCC,CCATCCCTCGGCCCA,CCATCCCTCTCCCCC,CCATCCCTCTCCCCA,CCATCCCTCTGCCCC,CCATCTCCCGGCCCC,CCATCTCCCGGCCCA,CCATCTCCCGCCCCC,CCATCTCCCTCCCCC,CCATCTCCCTCCCCA,CCATCTCCCTGCCCC,CCATCTCTCGGCCCC,CCATCTCTCCCCCCC,CCATCTCTCGCCCCC,CCATCTCTGGGCCCA,CCATCTCTCCCCCCA,CCATCTCTCGCCCCA,CCATCTCTCTCCCCA . . . GT 2/2 chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCC,CCATCTCTCTCCCCG,CCTTCTCTCTGCCCC,CCCTCTCTCTCCCCC,CCACCTCTCTGCCCC,CCACCCCTCTGCCCA,CCACCTCCCTCCCCC,CCACCTCCCTGCCCA,CCACCTCTCGGCCCC,CCACCTCTCGGCCCA,CCACCTCTCTCCCCC,CCACCTCTCTCCCCA,CCATCCCCCTCCCCC,CCATCCCCCTGCCCC,CCATCCCCCTGCCCA,CCATCCCTCGGCCCC,CCATCCCTCGGCCCA,CCATCCCTCTCCCCC,CCATCCCTCTCCCCA,CCATCCCTCTGCCCC,CCATCTCCCGGCCCC,CCATCTCCCGGCCCA,CCATCTCCCGCCCCC,CCATCTCCCTCCCCC,CCATCTCCCTCCCCA,CCATCTCCCTGCCCC,CCATCTCTCGGCCCC,CCATCTCTCCCCCCC,CCATCTCTCGCCCCC,CCATCTCTGGGCCCA,CCATCTCTCCCCCCA,CCATCTCTCGCCCCA,CCATCTCTCTCCCCA,CCTTCTCTCTGCCCC . . . GT 2/2 chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCC,CCATCTCTCTCCCCG,CCTTCTCTCTGCCCC,CCCTCTCTCTCCCCC,CCACCTCTCTGCCCC,CCACCCCTCTGCCCA,CCACCTCCCTCCCCC,CCACCTCTCGGCCCC,CCACCTCTCGGCCCA,CCACCTCTCTCCCCC,CCACCTCTCTCCCCA,CCATCCCCCTCCCCC,CCATCCCCCTGCCCC,CCATCCCCCTGCCCA,CCATCCCTCGGCCCC,CCATCCCTCGGCCCA,CCATCCCTCTCCCCC,CCATCCCTCTCCCCA,CCATCCCTCTGCCCC,CCATCTCCCGGCCCC,CCATCTCCCGGCCCA,CCATCTCCCGCCCCC,CCATCTCCCTCCCCC,CCATCTCCCTCCCCA,CCATCTCCCTGCCCC,CCATCTCTCGGCCCC,CCATCTCTCCCCCCC,CCATCTCTCGCCCCC,CCATCTCTGGGCCCA,CCATCTCTCCCCCCA,CCATCTCTCGCCCCA,CCATCTCTCTCCCCA,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC . . . GT 2/2 bcftools-1.21/test/mendelian.1.out000066400000000000000000000026151467060157400170710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 100 . A G 100 PASS . GT 0/0 0/0 0/0 1 101 . A G 100 PASS . GT ./. ./. ./. 1 102 . A G 100 PASS . GT ./. ./. ./. 1 103 . A G 100 PASS . GT ./. ./. ./. 1 104 . A G 100 PASS . GT . ./. ./. 1 105 . A G 100 PASS . GT . 0/0 0/1 2 200 . A G 100 PASS . GT 0/0 0/1 0/0 2 201 . A G 100 PASS . GT 0/0 0/1 0/1 2 202 . A G 100 PASS . GT ./. ./. ./. 3 300 . A G 100 PASS . GT ./. ./. ./. 3 301 . A G 100 PASS . GT 0/0 1/1 0/1 3 302 . A G 100 PASS . GT ./. ./. ./. 4 400 . A G 100 PASS . GT 0/1 0/0 0/0 4 401 . A G 100 PASS . GT 0/1 0/0 0/1 4 402 . A G 100 PASS . GT ./. ./. ./. 5 500 . A G 100 PASS . GT 0/1 0/1 0/0 5 501 . A G 100 PASS . GT 0/1 0/1 0/1 5 502 . A G 100 PASS . GT 0/1 0/1 1/1 6 600 . A G 100 PASS . GT ./. ./. ./. 6 601 . A G 100 PASS . GT 0/1 1/1 0/1 6 602 . A G 100 PASS . GT 0/1 1/1 1/1 X 100 . A G 100 PASS . GT 0/0 1 0 X 101 . A G 100 PASS . GT ./. . . X 102 . A G 100 PASS . GT 0/0 1 0/1 X 103 . A G 100 PASS . GT ./. . ./. X 104 . A G 100 PASS . GT . 0 1 X 105 . A G 100 PASS . GT . 0 0/1 Y 101 . A G 100 PASS . GT . 0 0 Y 102 . A G 100 PASS . GT . . . Y 103 . A G 100 PASS . GT . 0 . bcftools-1.21/test/mendelian.2.out000066400000000000000000000016631467060157400170740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 100 . A G 100 PASS . GT 0/0 0/0 0/0 1 105 . A G 100 PASS . GT . 0/0 0/1 2 200 . A G 100 PASS . GT 0/0 0/1 0/0 2 201 . A G 100 PASS . GT 0/0 0/1 0/1 3 301 . A G 100 PASS . GT 0/0 1/1 0/1 4 400 . A G 100 PASS . GT 0/1 0/0 0/0 4 401 . A G 100 PASS . GT 0/1 0/0 0/1 5 500 . A G 100 PASS . GT 0/1 0/1 0/0 5 501 . A G 100 PASS . GT 0/1 0/1 0/1 5 502 . A G 100 PASS . GT 0/1 0/1 1/1 6 601 . A G 100 PASS . GT 0/1 1/1 0/1 6 602 . A G 100 PASS . GT 0/1 1/1 1/1 X 100 . A G 100 PASS . GT 0/0 1 0 X 102 . A G 100 PASS . GT 0/0 1 0/1 X 104 . A G 100 PASS . GT . 0 1 X 105 . A G 100 PASS . GT . 0 0/1 Y 101 . A G 100 PASS . GT . 0 0 bcftools-1.21/test/mendelian.3.out000066400000000000000000000013771467060157400170770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 101 . A G 100 PASS . GT 0/0 0/0 0/1 1 102 . A G 100 PASS . GT 0/0 0/0 1/1 1 103 . A G 100 PASS . GT ./. 0/0 1/1 1 104 . A G 100 PASS . GT . 0/0 1/1 2 202 . A G 100 PASS . GT 0/0 0/1 1/1 3 300 . A G 100 PASS . GT 0/0 1/1 0/0 3 302 . A G 100 PASS . GT 0/0 1/1 1/1 4 402 . A G 100 PASS . GT 0/1 0/0 1/1 6 600 . A G 100 PASS . GT 0/1 1/1 0/0 X 101 . A G 100 PASS . GT 0/0 1 1 X 103 . A G 100 PASS . GT 0/0 0 0/1 Y 102 . A G 100 PASS . GT . 0 1 bcftools-1.21/test/mendelian.4.out000066400000000000000000000031761467060157400170770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 100 . A G 100 PASS MERR=0 GT 0/0 0/0 0/0 1 101 . A G 100 PASS MERR=1 GT 0/0 0/0 0/1 1 102 . A G 100 PASS MERR=1 GT 0/0 0/0 1/1 1 103 . A G 100 PASS MERR=1 GT ./. 0/0 1/1 1 104 . A G 100 PASS MERR=1 GT . 0/0 1/1 1 105 . A G 100 PASS MERR=0 GT . 0/0 0/1 2 200 . A G 100 PASS MERR=0 GT 0/0 0/1 0/0 2 201 . A G 100 PASS MERR=0 GT 0/0 0/1 0/1 2 202 . A G 100 PASS MERR=1 GT 0/0 0/1 1/1 3 300 . A G 100 PASS MERR=1 GT 0/0 1/1 0/0 3 301 . A G 100 PASS MERR=0 GT 0/0 1/1 0/1 3 302 . A G 100 PASS MERR=1 GT 0/0 1/1 1/1 4 400 . A G 100 PASS MERR=0 GT 0/1 0/0 0/0 4 401 . A G 100 PASS MERR=0 GT 0/1 0/0 0/1 4 402 . A G 100 PASS MERR=1 GT 0/1 0/0 1/1 5 500 . A G 100 PASS MERR=0 GT 0/1 0/1 0/0 5 501 . A G 100 PASS MERR=0 GT 0/1 0/1 0/1 5 502 . A G 100 PASS MERR=0 GT 0/1 0/1 1/1 6 600 . A G 100 PASS MERR=1 GT 0/1 1/1 0/0 6 601 . A G 100 PASS MERR=0 GT 0/1 1/1 0/1 6 602 . A G 100 PASS MERR=0 GT 0/1 1/1 1/1 X 100 . A G 100 PASS MERR=0 GT 0/0 1 0 X 101 . A G 100 PASS MERR=1 GT 0/0 1 1 X 102 . A G 100 PASS MERR=0 GT 0/0 1 0/1 X 103 . A G 100 PASS MERR=1 GT 0/0 0 0/1 X 104 . A G 100 PASS MERR=0 GT . 0 1 X 105 . A G 100 PASS MERR=0 GT . 0 0/1 Y 101 . A G 100 PASS MERR=0 GT . 0 0 Y 102 . A G 100 PASS MERR=1 GT . 0 1 Y 103 . A G 100 PASS MERR=0 GT . 0 . bcftools-1.21/test/mendelian.5.out000066400000000000000000000005451467060157400170750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 Y 103 . A G 100 PASS . GT . 0 . bcftools-1.21/test/mendelian.6.out000066400000000000000000000015151467060157400170740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 100 . A G 100 PASS . GT 0/0 0/0 0/0 2 200 . A G 100 PASS . GT 0/0 0/1 0/0 2 201 . A G 100 PASS . GT 0/0 0/1 0/1 3 301 . A G 100 PASS . GT 0/0 1/1 0/1 4 400 . A G 100 PASS . GT 0/1 0/0 0/0 4 401 . A G 100 PASS . GT 0/1 0/0 0/1 5 500 . A G 100 PASS . GT 0/1 0/1 0/0 5 501 . A G 100 PASS . GT 0/1 0/1 0/1 5 502 . A G 100 PASS . GT 0/1 0/1 1/1 6 601 . A G 100 PASS . GT 0/1 1/1 0/1 6 602 . A G 100 PASS . GT 0/1 1/1 1/1 X 100 . A G 100 PASS . GT 0/0 1 0 X 102 . A G 100 PASS . GT 0/0 1 0/1 Y 101 . A G 100 PASS . GT . 0 0 bcftools-1.21/test/mendelian.7.out000066400000000000000000000010251467060157400170710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 103 . A G 100 PASS . GT ./. 0/0 1/1 1 104 . A G 100 PASS . GT . 0/0 1/1 1 105 . A G 100 PASS . GT . 0/0 0/1 X 104 . A G 100 PASS . GT . 0 1 X 105 . A G 100 PASS . GT . 0 0/1 Y 103 . A G 100 PASS . GT . 0 . bcftools-1.21/test/mendelian.8.out000066400000000000000000000010761467060157400171000ustar00rootroot00000000000000sites_ref_only 0 # sites skipped because there was no ALT allele sites_many_als 0 # skipped because of too many ALT alleles sites_fail 0 # skipped because of failed -i/-e filter sites_no_GT 0 # skipped because of absent FORMAT/GT field sites_not_diploid 0 # skipped because FORMAT/GT not formatted diploid sites_missing 6 # number of sites with at least one trio GT missing sites_merr 12 # number of sites with at least one Mendelian error sites_good 14 # number of sites with at least one good trio ngood 14 ngood_alt 11 nmerr 12 nmissing 6 nfail 0 TRIO 1 child1 dad1 mom1 bcftools-1.21/test/mendelian.vcf000066400000000000000000000025311467060157400166760ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 1 100 . A G 100 PASS . GT 0/0 0/0 0/0 1 101 . A G 100 PASS . GT 0/0 0/0 0/1 1 102 . A G 100 PASS . GT 0/0 0/0 1/1 1 103 . A G 100 PASS . GT ./. 0/0 1/1 1 104 . A G 100 PASS . GT . 0/0 1/1 1 105 . A G 100 PASS . GT . 0/0 0/1 2 200 . A G 100 PASS . GT 0/0 0/1 0/0 2 201 . A G 100 PASS . GT 0/0 0/1 0/1 2 202 . A G 100 PASS . GT 0/0 0/1 1/1 3 300 . A G 100 PASS . GT 0/0 1/1 0/0 3 301 . A G 100 PASS . GT 0/0 1/1 0/1 3 302 . A G 100 PASS . GT 0/0 1/1 1/1 4 400 . A G 100 PASS . GT 0/1 0/0 0/0 4 401 . A G 100 PASS . GT 0/1 0/0 0/1 4 402 . A G 100 PASS . GT 0/1 0/0 1/1 5 500 . A G 100 PASS . GT 0/1 0/1 0/0 5 501 . A G 100 PASS . GT 0/1 0/1 0/1 5 502 . A G 100 PASS . GT 0/1 0/1 1/1 6 600 . A G 100 PASS . GT 0/1 1/1 0/0 6 601 . A G 100 PASS . GT 0/1 1/1 0/1 6 602 . A G 100 PASS . GT 0/1 1/1 1/1 X 100 . A G 100 PASS . GT 0/0 1 0 X 101 . A G 100 PASS . GT 0/0 1 1 X 102 . A G 100 PASS . GT 0/0 1 0/1 X 103 . A G 100 PASS . GT 0/0 0 0/1 X 104 . A G 100 PASS . GT . 0 1 X 105 . A G 100 PASS . GT . 0 0/1 Y 101 . A G 100 PASS . GT . 0 0 Y 102 . A G 100 PASS . GT . 0 1 Y 103 . A G 100 PASS . GT . 0 . bcftools-1.21/test/merge.10.1.out000066400000000000000000000010161467060157400164450ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b 1 3000000 . C CCG . . . GT 0/1 ./. 1 3000000 . C CAA . . . GT ./. 0/1 1 3000150 . CC C . . . GT 0/1 ./. 1 3000150 . C CTT . . . GT ./. 0/1 1 3000152 . C A . . . GT 0/1 ./. 1 3000152 . C CA . . . GT ./. 0/1 1 3000154 . C A . . . GT 0/1 ./. 1 3000154 . C T . . . GT ./. 0/1 bcftools-1.21/test/merge.10.2.out000066400000000000000000000006621467060157400164540ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b 1 3000000 . C CCG,CAA . . . GT 0/1 0/2 1 3000150 . CC C,CTTC . . . GT 0/1 0/2 1 3000152 . C A . . . GT 0/1 ./. 1 3000152 . C CA . . . GT ./. 0/1 1 3000154 . C A,T . . . GT 0/1 0/2 bcftools-1.21/test/merge.10.3.out000066400000000000000000000007201467060157400164500ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b 1 3000000 . C CCG,CAA . . . GT 0/1 0/2 1 3000150 . CC C . . . GT 0/1 ./. 1 3000150 . C CTT . . . GT ./. 0/1 1 3000152 . C A . . . GT 0/1 ./. 1 3000152 . C CA . . . GT ./. 0/1 1 3000154 . C A,T . . . GT 0/1 0/2 bcftools-1.21/test/merge.10.a.vcf000066400000000000000000000004771467060157400165060ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a 1 3000000 . C CCG . . . GT 0/1 1 3000150 . CC C . . . GT 0/1 1 3000152 . C A . . . GT 0/1 1 3000154 . C A . . . GT 0/1 bcftools-1.21/test/merge.10.b.vcf000066400000000000000000000005011467060157400164730ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT b 1 3000000 . C CAA . . . GT 0/1 1 3000150 . C CTT . . . GT 0/1 1 3000152 . C CA . . . GT 0/1 1 3000154 . C T . . . GT 0/1 bcftools-1.21/test/merge.11.1.out000066400000000000000000000017341467060157400164550ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://ref/Zmays_493_APGv4.fa ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 1 2 3 4 5 6 24 25 26 27 28 29 1 5695120 . C T 863.255 . . GT:AD ./.:0,0 0/0:389,0 0/0:475,0 0/0:597,0 0/0:262,0 0/0:1428,0 0/0:26,0 0/0:1279,0 0/0:820,0 0/0:616,0 0/0:123,0 0/0:1026,0 1 6070233 . G C,A 10355.5 . . GT:AD 0/0:918,1,0 1/1:0,19,0 1/1:1,355,0 0/2:181,1,136 1/1:0,634,0 0/0:1219,0,0 1/1:0,365,. 1/1:1,428,. 0/0:751,0,. 1/1:1,837,. 0/0:308,1,. 1/1:0,1113,. 1 7988614 . C T 1143.54 . . GT:AD 0/0:441,. 0/0:278,. 0/0:722,. 0/0:614,. 0/0:321,. 0/0:515,. 0/0:2,0 0/0:600,0 0/0:769,0 0/0:450,0 0/0:300,0 0/0:166,0 1 11301504 . C . 22.0947 . . GT:AD 0/0:81 0/0:136 ./.:0 0/0:161 0/0:417 0/0:241 0/0:178 0/0:226 0/0:32 0/0:138 ./.:0 0/0:353 bcftools-1.21/test/merge.11.a.vcf000066400000000000000000000012341467060157400164770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://ref/Zmays_493_APGv4.fa ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 1 2 3 4 5 6 1 5695120 . C T 665.34 . . GT:AD ./.:0,0 0/0:389,0 0/0:475,0 0/0:597,0 0/0:262,0 0/0:1428,0 1 6070233 . G C,A 10355.5 . . GT:AD 0/0:918,1,0 1/1:0,19,0 1/1:1,355,0 0/2:181,1,136 1/1:0,634,0 0/0:1219,0,0 1 7988614 . C . 22.0485 . . GT:AD 0/0:441 0/0:278 0/0:722 0/0:614 0/0:321 0/0:515 1 11301504 . C . 22.0947 . . GT:AD 0/0:81 0/0:136 ./.:0 0/0:161 0/0:417 0/0:241 bcftools-1.21/test/merge.11.b.vcf000066400000000000000000000012401467060157400164750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://ref/Zmays_493_APGv4.fa ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 24 25 26 27 28 29 1 5695120 . C T 863.255 . . GT:AD 0/0:26,0 0/0:1279,0 0/0:820,0 0/0:616,0 0/0:123,0 0/0:1026,0 1 6070233 . G C 4730.75 . . GT:AD 1/1:0,365 1/1:1,428 0/0:751,0 1/1:1,837 0/0:308,1 1/1:0,1113 1 7988614 . C T 1143.54 . . GT:AD 0/0:2,0 0/0:600,0 0/0:769,0 0/0:450,0 0/0:300,0 0/0:166,0 1 11301504 . C . 22.0179 . . GT:AD 0/0:178 0/0:226 0/0:32 0/0:138 ./.:0 0/0:353 bcftools-1.21/test/merge.2.a.vcf000066400000000000000000000036171467060157400164260ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000150 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000151 . C A 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3106154 . C CC 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3106154 . C A 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3200000 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3200010 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 bcftools-1.21/test/merge.2.all.out000066400000000000000000000042131467060157400170000ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B 1 3000000 . C CCG,G 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 1 3000150 . C A,G 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 1 3000151 . C A,G 59.2 PASS AN=8;AC=2,2 GT:DP:GQ 0/1:32:245 0/1:32:245 0/2:32:245 0/2:32:245 1 3106154 . C CC,CCC 342 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3106154 . C A,T 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3200000 . C T 59.2 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/1:245:32 0/1:245:32 1 3200010 . C T,A 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 ./.:1,2,3,4,5,6 .:1,2,3 bcftools-1.21/test/merge.2.b.vcf000066400000000000000000000036221467060157400164230ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000000 . C G 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000150 . C G 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000151 . C G 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3106154 . C CCC 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3106154 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3200000 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3200010 . c A,T 59.2 PASS AN=4;AC=2,0 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3200020 . C T,G 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,4,6,2,5,3 .:1,3,2 bcftools-1.21/test/merge.2.both.out000066400000000000000000000043111467060157400171630ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B 1 3000000 . C G 59.2 PASS AN=4;AC=2 GT:GQ ./.:. ./.:. 0/1:245 0/1:245 1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. 1 3000150 . C A,G 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 1 3000151 . C A,G 59.2 PASS AN=8;AC=2,2 GT:DP:GQ 0/1:32:245 0/1:32:245 0/2:32:245 0/2:32:245 1 3106154 . C A,T 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3106154 . C CC,CCC 342 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3200000 . C T 59.2 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/1:245:32 0/1:245:32 1 3200010 . C T,A 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 ./.:1,2,3,4,5,6 .:1,2,3 bcftools-1.21/test/merge.2.none.out000066400000000000000000000047411467060157400171750ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B 1 3000000 . C G 59.2 PASS AN=4;AC=2 GT:GQ ./.:. ./.:. 0/1:245 0/1:245 1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. 1 3000150 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. 1 3000150 . C G 59.2 PASS AN=4;AC=2 GT:GQ ./.:. ./.:. 0/1:245 0/1:245 1 3000151 . C A 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 ./.:.:. ./.:.:. 1 3000151 . C G 59.2 PASS AN=4;AC=2 GT:DP:GQ ./.:.:. ./.:.:. 0/1:32:245 0/1:32:245 1 3106154 . C A 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. ./.:.:. 1 3106154 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP ./.:.:. ./.:.:. 0/1:245:32 0/1:245:32 1 3106154 . C CC 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. ./.:.:. 1 3106154 . C CCC 342 PASS AN=4;AC=2 GT:GQ:DP ./.:.:. ./.:.:. 0/1:245:32 0/1:245:32 1 3200000 . C T 59.2 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/1:245:32 0/1:245:32 1 3200010 . C T,A 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 ./.:1,2,3,4,5,6 .:1,2,3 bcftools-1.21/test/merge.3.a.vcf000066400000000000000000000032031467060157400164160ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000000 . C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ 0/1:245 0/1:245 bcftools-1.21/test/merge.3.b.vcf000066400000000000000000000032101467060157400164150ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000000 . C CG 59.2 PASS AN=4;AC=2;TR=10,20;TA=10;TG=10,20,30 GT:GQ 0/1:245 0/1:245 bcftools-1.21/test/merge.3.out000066400000000000000000000033441467060157400162360ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B 1 3000000 . C CCG,CG 59.2 PASS TA=1,10;TG=11,2,3,20,0,30;TR=11,2,20;AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 bcftools-1.21/test/merge.4.a.vcf000066400000000000000000000043651467060157400164310ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000000 id1 C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XA:XG 0/1:245:0,1:1:0,1,2 0/1:245:1,2:2:0,1,2 1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ:XR:XA:XG 0/1:245:1,2:2:0,1,2 0/1:245:2,3:3:1,2,3 1 3000002 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000002 id2 C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GL:XR:XA:XG 0/1:245,0,199:.:.:. 0/1:245,0,199:.:.:. 1 3000002 id3 C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GL:XR:XA:XG 0/1:245,0,245:.:.:. 0/1:245,0,245:. bcftools-1.21/test/merge.4.b.vcf000066400000000000000000000042641467060157400164300ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D 1 3000000 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000000 id1 C A 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XG:XA 0/1:245:4,5:3,4,5:5 0/1:245:6,7:6,7,8:7 1 3000002 id3 C A 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XG:XA 0/1:245:. 0/1:245:1,2:1,2,3:2 1 3000002 id2 C A 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XG:XA 0/1:245:. 0/1:245:.:.:. 1 3000002 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 bcftools-1.21/test/merge.4.out000066400000000000000000000051511467060157400162350ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 3000000 id1 C CCG,A 59.2 PASS TR=1,2,2;TA=1,1;TG=1,2,3,2,.,3;AN=8;AC=2,2 GT:GQ:XR:XA:XG 0/1:245:0,1,.:1,.:0,1,2,.,.,. 0/1:245:1,2,.:2,.:0,1,2,.,.,. 0/2:245:4,.,5:.,5:3,.,.,4,.,5 0/2:245:6,.,7:.,7:6,.,.,7,.,8 1 3000000 . C CCG,A 59.2 PASS AN=8;AC=2,2 GT:GQ:XR:XA:XG 0/1:245:1,2,.:2,.:0,1,2,.,.,. 0/1:245:2,3,.:3,.:1,2,3,.,.,. 0/2:245:.:.:. 0/2:245:.:.:. 1 3000002 . C CCG,A 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 1 3000002 id2 C CCG,A 59.2 PASS TR=1,2,2;TA=1,1;TG=1,2,3,2,.,3;AN=8;AC=2,2 GT:GL:XR:XA:XG:GQ 0/1:245,0,199,.,.,.:.:.:.:. 0/1:245,0,199,.,.,.:.:.:.:. 0/2:.:.:.:.:245 0/2:.:.:.:.:245 1 3000002 id3 C CCG,A 59.2 PASS TR=1,2,2;TA=1,1;TG=1,2,3,2,.,3;AN=8;AC=2,2 GT:GL:XR:XA:XG:GQ 0/1:245,0,245,.,.,.:.:.:.:. 0/1:245,0,245,.,.,.:.:.:.:. 0/2:.:.:.:.:245 0/2:.:1,.,2:.,2:1,.,.,2,.,3:245 bcftools-1.21/test/merge.5.a.vcf000066400000000000000000000005331467060157400164230ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t1 1 11080563 . AACACAC A,AAC 4321.7 . . GT 0/2 1 11080564 . ACACAC AACAC,* 5809.43 . . GT 0/1 1 11080566 . ACACAC A,AAC,* 5215.77 . . GT 0/2 bcftools-1.21/test/merge.5.b.vcf000066400000000000000000000004621467060157400164250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t2 1 11080564 . ACACACAC AACACAC,* 6150.42 . . GT 0/1 1 11080566 . ACACAC A,AAC,* 5296.77 . . GT 0/2 bcftools-1.21/test/merge.5.out000066400000000000000000000006421467060157400162360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t1 t2 1 11080563 . AACACAC A,AAC 4321.7 . . GT 0/2 ./. 1 11080564 . ACACACAC AACACAC,* 6150.42 . . GT 0/1 0/1 1 11080566 . ACACAC A,AAC,* 5296.77 . . GT 0/2 0/2 bcftools-1.21/test/merge.6.a.vcf000066400000000000000000000006541467060157400164300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t1 1 11080563 . A C . . . GT:RFS:AFS 0/1:aa,c:c 1 11080564 . A C . . . GT:RFS:AFS 0/1:a,cc:c bcftools-1.21/test/merge.6.b.vcf000066400000000000000000000010461467060157400164250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t2 1 11080563 . A C . . . GT:FFS:AFS:RFS 0/1:xx,yy:C:A,C 1 11080564 . A T . . . GT:FFS:AFS:RFS 0/1:xx,yy:TTTTATGCATGCATGCTTTTTTTTATGCATGCATGCTTTT:A,T bcftools-1.21/test/merge.6.out000066400000000000000000000012011467060157400162270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t1 t2 1 11080563 . A C . . . GT:RFS:AFS:FFS 0/1:aa,c:c:. 0/1:A,C:C:xx,yy 1 11080564 . A C,T . . . GT:RFS:AFS:FFS 0/1:a,cc,.:c,.:. 0/2:A,.,T:.,TTTTATGCATGCATGCTTTTTTTTATGCATGCATGCTTTT:xx,yy bcftools-1.21/test/merge.7.a.vcf000066400000000000000000000004131467060157400164220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 2:2:A 2:2:2:A 1 11080563 . A C . . . GT 0/1 0/1 0/1 0/1 bcftools-1.21/test/merge.7.b.vcf000066400000000000000000000004131467060157400164230ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 2:2:A 2:2:2:A 1 11080563 . A C . . . GT 0/1 0/1 0/1 0/1 bcftools-1.21/test/merge.8.a.vcf000066400000000000000000000005121467060157400164230ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . C G . . AN=4;AC=2 bcftools-1.21/test/merge.8.b.vcf000066400000000000000000000005121467060157400164240ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . C T . . AN=4;AC=1 bcftools-1.21/test/merge.8.out000066400000000000000000000006021467060157400162350ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . C G,T . . AC=2,1;AN=8 bcftools-1.21/test/merge.9.1.out000066400000000000000000000007261467060157400164040ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 10 . C G,T . . AN=4;AC=2,0 GT 0/0 1/1 bcftools-1.21/test/merge.9.2.out000066400000000000000000000007261467060157400164050ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 10 . C G,T . . AC=2,1;AN=8 GT 0/0 1/1 bcftools-1.21/test/merge.9.a.vcf000066400000000000000000000006361467060157400164330ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 10 . C G . . AN=4;AC=2 GT 0/0 1/1 bcftools-1.21/test/merge.9.b.vcf000066400000000000000000000006101467060157400164240ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##reference=file:///ref.fa ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . C T . . AN=4;AC=1 bcftools-1.21/test/merge.9.out000066400000000000000000000006031467060157400162370ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##reference=file:///home/dnanexus/genome.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 2:2:A 2:2:2:A 2:2:2:2:A 2:2:2:2:2:A 2:2:2:2:2:2:A 2:2:2:2:2:2:2:A 1 11080563 . A C . . . GT 0/1 0/1 0/1 0/1 0/1 0/1 0/1 0/1 bcftools-1.21/test/merge.LPL.0.out000066400000000000000000000017011467060157400166540ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10:10,0,10:1,2:0.1,0.2:1 1 30002 . C CA,CAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2 1 30003 . C CA,CAA,CAAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.1.out000066400000000000000000000040111467060157400166520ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 3:A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA,CC,CG . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10,.,.,.,.,.,.,.:10,0,10,.,.,.,.,.,.,.:1,2,.,.:0.1,0.2,.,.:1,.,. 0/2:10,.,.,0,.,10,.,.,.,.:10,.,.,0,.,10,.,.,.,.:1,.,2,.:0.1,.,0.2,.:.,1,. 0/3:10,.,.,.,.,.,0,.,.,10:10,.,.,.,.,.,0,.,.,10:1,.,.,2:0.1,.,.,0.2:.,.,1 1 30002 . C CA,CAA,CC,CCC,CG,CGG . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.:20,20,20,10,0,10,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.:0,1,2,.,.,.,.:0,0.1,0.2,.,.,.,.:1,2,.,.,.,. 3/4:20,.,.,.,.,.,20,.,.,20,10,.,.,0,10,.,.,.,.,.,.,.,.,.,.,.,.,.:20,.,.,.,.,.,20,.,.,20,10,.,.,0,10,.,.,.,.,.,.,.,.,.,.,.,.,.:0,.,.,1,2,.,.:0,.,.,0.1,0.2,.,.:.,.,1,2,.,. 5/6:20,.,.,.,.,.,.,.,.,.,.,.,.,.,.,20,.,.,.,.,20,10,.,.,.,.,0,10:20,.,.,.,.,.,.,.,.,.,.,.,.,.,.,20,.,.,.,.,20,10,.,.,.,.,0,10:0,.,.,.,.,1,2:0,.,.,.,.,0.1,0.2:.,.,.,.,1,2 1 30003 . C CA,CAA,CAAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. ./.:.:.:.:.:. 1 30004 . C CC,CCC,CCCC . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. 1 30005 . C CG,CGG,CGGG . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.2.out000066400000000000000000000036761467060157400166730ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 3:A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA,CC,CG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 0/1:10,0,10:10,0,10:1,2:0.1,0.2:1:1 0/2:10,0,10:10,0,10:1,2:0.1,0.2:1:2 0/3:10,0,10:10,0,10:1,2:0.1,0.2:1:3 1 30002 . C CA,CAA,CC,CCC,CG,CGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,10,10:20,10,10:0,2:0,0.2:2:2 3/4:20,10,10:20,10,10:0,2:0,0.2:2:4 5/6:20,10,10:20,10,10:0,2:0,0.2:2:6 1 30003 . C CA,CAA,CAAA . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,10,10:20,10,10:0,2:0,0.2:2:2 ./.:.:.:.:.:.:. ./.:.:.:.:.:.:. 1 30004 . C CC,CCC,CCCC . . . GT:LPL:LGL:LAD:LDF:LDD:LAA ./.:.:.:.:.:.:. 1/2:20,10,10:20,10,10:0,2:0,0.2:2:2 ./.:.:.:.:.:.:. 1 30005 . C CG,CGG,CGGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA ./.:.:.:.:.:.:. ./.:.:.:.:.:.:. 1/2:20,10,10:20,10,10:0,2:0,0.2:2:2 bcftools-1.21/test/merge.LPL.3.out000066400000000000000000000041401467060157400166570ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 3:A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA,CC,CG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 0/1:10,0,10:10,0,10:1,2:0.1,0.2:1:1 0/2:10,0,10:10,0,10:1,2:0.1,0.2:1:2 0/3:10,0,10:10,0,10:1,2:0.1,0.2:1:3 1 30002 . C CA,CAA,CC,CCC,CG,CGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 3/4:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:3,4 5/6:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:5,6 1 30003 . C CA,CAA,CAAA . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 ./.:.:.:.:.:.:.,. ./.:.:.:.:.:.:. 1 30004 . C CC,CCC,CCCC . . . GT:LPL:LGL:LAD:LDF:LDD:LAA ./.:.:.:.:.:.:. 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 ./.:.:.:.:.:.:.,2 1 30005 . C CG,CGG,CGGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA ./.:.:.:.:.:.:. ./.:.:.:.:.:.:.,. 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 bcftools-1.21/test/merge.LPL.4.out000066400000000000000000000043601467060157400166640ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 3:A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA,CC,CG . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10,.,.,.,.,.,.,.:10,0,10,.,.,.,.,.,.,.:1,2,.,.:0.1,0.2,.,.:1,.,. 0/2:10,.,.,0,.,10,.,.,.,.:10,.,.,0,.,10,.,.,.,.:1,.,2,.:0.1,.,0.2,.:.,1,. 0/3:10,.,.,.,.,.,0,.,.,10:10,.,.,.,.,.,0,.,.,10:1,.,.,2:0.1,.,.,0.2:.,.,1 1 30002 . C CA,CAA,CC,CCC,CG,CGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 3/4:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:3,4 5/6:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:5,6 1 30003 . C CA,CAA,CAAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. ./.:.:.:.:.:. 1 30004 . C CC,CCC,CCCC . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. 1 30005 . C CG,CGG,CGGG . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.5.out000066400000000000000000000043601467060157400166650ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 3:A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA,CC,CG . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10,.,.,.,.,.,.,.:10,0,10,.,.,.,.,.,.,.:1,2,.,.:0.1,0.2,.,.:1,.,. 0/2:10,.,.,0,.,10,.,.,.,.:10,.,.,0,.,10,.,.,.,.:1,.,2,.:0.1,.,0.2,.:.,1,. 0/3:10,.,.,.,.,.,0,.,.,10:10,.,.,.,.,.,0,.,.,10:1,.,.,2:0.1,.,.,0.2:.,.,1 1 30002 . C CA,CAA,CC,CCC,CG,CGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 3/4:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:3,4 5/6:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:5,6 1 30003 . C CA,CAA,CAAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. ./.:.:.:.:.:. 1 30004 . C CC,CCC,CCCC . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. 1 30005 . C CG,CGG,CGGG . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.6.out000066400000000000000000000043601467060157400166660ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 2:A 3:A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA,CC,CG . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10,.,.,.,.,.,.,.:10,0,10,.,.,.,.,.,.,.:1,2,.,.:0.1,0.2,.,.:1,.,. 0/2:10,.,.,0,.,10,.,.,.,.:10,.,.,0,.,10,.,.,.,.:1,.,2,.:0.1,.,0.2,.:.,1,. 0/3:10,.,.,.,.,.,0,.,.,10:10,.,.,.,.,.,0,.,.,10:1,.,.,2:0.1,.,.,0.2:.,.,1 1 30002 . C CA,CAA,CC,CCC,CG,CGG . . . GT:LPL:LGL:LAD:LDF:LDD:LAA 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:1,2 3/4:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:3,4 5/6:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2:5,6 1 30003 . C CA,CAA,CAAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. ./.:.:.:.:.:. 1 30004 . C CC,CCC,CCCC . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 ./.:.:.:.:.:. 1 30005 . C CG,CGG,CGGG . . . GT:PL:GL:AD:DF:DD ./.:.:.:.:.:. ./.:.:.:.:.:. 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.a.vcf000066400000000000000000000016151467060157400167100ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CA . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10:10,0,10:1,2:0.1,0.2:1 1 30002 . C CA,CAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2 1 30003 . C CA,CAA,CAAA . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.b.vcf000066400000000000000000000016151467060157400167110ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CC . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10:10,0,10:1,2:0.1,0.2:1 1 30002 . C CC,CCC . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2 1 30004 . C CC,CCC,CCCC . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.LPL.c.vcf000066400000000000000000000016151467060157400167120ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 30000 . C T . . . GT:PL:GL:AD:DF:DD 0/1:20,0,20:20,0,20:1,2:0.1,0.2:1 1 30001 . C CG . . . GT:PL:GL:AD:DF:DD 0/1:10,0,10:10,0,10:1,2:0.1,0.2:1 1 30002 . C CG,CGG . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10:20,20,20,10,0,10:0,1,2:0,0.1,0.2:1,2 1 30005 . C CG,CGG,CGGG . . . GT:PL:GL:AD:DF:DD 1/2:20,20,20,10,0,10,20,20,10,20:20,20,20,10,0,10,20,20,10,20:0,1,2,1:0,0.1,0.2,0.1:1,2,3 bcftools-1.21/test/merge.a.chk000066400000000000000000000030111467060157400162410ustar00rootroot00000000000000# This file was produced by vcfcheck and can be plotted using plot-vcfcheck. # # Definition of sets: # ID [2]id [3]tab-separated file names # SN, Summary numbers: # SN [2]id [3]key [4]value SN 0 number of samples: 2 SN 0 number of SNPs: 1 SN 0 number of MNPs: 0 SN 0 number of indels: 10 SN 0 number of others: 0 SN 0 number of multiallelic sites: 4 SN 0 ts/tv: 0.00 # Sis, Singleton stats: # SiS [2]id [3]allele count [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels SiS 0 1 2 0 2 0 # AF, Stats by non-reference allele frequency: # AF [2]id [3]allele frequency [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels AF 0 0.000000 2 0 2 0 AF 0 49.494949 0 0 0 12 AF 0 100.000000 0 0 0 1 # IDD, InDel distribution: # IDD [2]id [3]length (deletions negative) [4]count IDD 0 -8 1 IDD 0 -4 1 IDD 0 -3 3 IDD 0 -2 2 IDD 0 -1 3 IDD 0 1 2 IDD 0 2 1 # ST, Substitution types: # ST [2]id [3]type [4]count ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 0 ST 0 C>G 0 ST 0 C>T 0 ST 0 G>A 0 ST 0 G>C 1 ST 0 G>T 1 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 # PSC, Per-sample counts # PSC [2]id [3]sample [4]nRefHom [5]nNonRefHom [6]nHets [7]nTransitions [8]nTransversions [9]nIndels [10]average depth PSC 0 A 0 0 1 0 1 10 27 PSC 0 B 0 0 1 0 1 10 27 # DP, Depth distribution # DP [2]id [3]bin [4]number of genotypes [5]fraction of genotypes (%) DP 0 10 2 9.090909 DP 0 21 2 9.090909 DP 0 22 2 9.090909 DP 0 26 4 18.181818 DP 0 30 2 9.090909 DP 0 31 2 9.090909 DP 0 32 4 18.181818 DP 0 35 4 18.181818 bcftools-1.21/test/merge.a.vcf000066400000000000000000000046731467060157400162710ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:212:22 1 3177144 . G T 45 PASS AN=4;AC=2 GT:GQ:DP 0/0:150:30 1/1:150:30 1 3177144 . G . 45 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:10 2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 4 3258448 . TACACACAC T . PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 bcftools-1.21/test/merge.abc.2.out000066400000000000000000000124471467060157400167650ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##FORMAT= ##FILTER= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:B C D 1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. ./.:. 1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 ./.:.:. ./.:.:. ./.:.:. 1 3062915 idSNP G T,C,A 419 test;q20 TEST=5;STR=.;DP=14;DP4=3,6,9,12;INTA=2,1,.;AN=9;AC=2,2,1 GT:TT:GQ:DP:GL:STR 0/1:0,1,.:409:35:-20,-5,-20,-20,-5,-20,.,.,.,.:. 2:0,1,.:409:35:-20,-5,-20,.:. 0/3:.:376:14:-10,.,.,.,.,.,0,.,.,-10:ABC 0/2:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 0/1:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 1 3062915 id3D GTTT G 84.6 q10;q20 INDEL;STR=test;TXT=AA;DP=1013;DP4=6,7,8,9;AN=10;AC=5 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:376:14:-10,0,-10 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 id1D;id2D GTT GT,G 999 q20;q10 DP=14;DP4=2,4,6,8;AN=6;AC=1,2 GT:GQ:DP:GL:STR ./.:.:.:.:. ./.:.:.:.:. 0/1:376:14:-10,0,-10,.,.,.:DEF 0/2:409:35:-20,.,.,-5,.,-20:. 0/2:409:35:-20,.,.,-5,.,-20:. 1 3106154 . C T 999 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL ./.:.:.:. ./.:.:.:. 0/1:277:15:-10,0,-10 ./.:.:.:. ./.:.:.:. 1 3106154 . CAAAA CA,C 342 PASS DP=15;AN=6;AC=2,1 GT:GQ:DP:GL 0/1:245:32:. 0/1:245:32:. 0/2:277:15:-10,.,.,0,.,-10 .:245:32:. ./.:245:32:. 1 3106154 . C CT 459 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. 0/1:245:32 0/1:245:32 1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP ./.:.:. ./.:.:. ./.:.:. 1/1:21:21 1/1:21:21 1 3157410 . GAC GC,G 90.6 PASS DP=11;AN=6;AC=4,1 GT:GQ:DP 1/1:21:21 1/1:21:21 0/2:49:11 ./.:.:. ./.:.:. 1 3162006 . GAA G,GA 238 PASS DP=19;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F;AN=10;AC=3,2 GT:GQ:DP 0/1:212:22 0/1:212:22 0/1:589:19 0/2:212:22 0/2:212:22 1 3177144 . G T 999 PASS DP=24;AN=10;AC=3 GT:GQ:DP 0/0:150:30 1/1:150:30 0/1:236:24 0/0:150:30 0/0:150:30 1 3177144 . GT G 999 PASS DP=24;AN=6;AC=1 GT:GQ:DP 0/0:150:30 0/0:150:30 0/1:236:24 ./.:.:. ./.:.:. 1 3184885 . TAAAA TA,T 61.5 PASS DP=16;AN=10;AC=5,4 GT:GQ:DP 1/2:12:10 1/2:12:10 0/1:435:16 1/2:12:10 1/2:12:10 2 3188209 . GA G 41.5 PASS DP=15;AN=2;AC=1 GT:GQ:DP ./.:.:. ./.:.:. 0/1:162:15 ./.:.:. ./.:.:. 2 3199812 . G GTT,GT 291 PASS AN=8;AC=4,4 GT:GQ:DP 1/2:322:26 1/2:322:26 ./.:.:. 1/2:322:26 1/2:322:26 3 3199812 . GA GTT,GT 17.5 PASS DP=19;AN=2;AC=1,1 GT:GQ:DP ./.:.:. ./.:.:. 1/2:188:19 ./.:.:. ./.:.:. 3 3212016 . CTT C,CT 79 PASS AN=8;AC=4,4 GT:GQ:DP 1/2:91:26 1/2:91:26 ./.:.:. 1/2:91:26 1/2:91:26 4 3212016 . CTT C 999 q20 DP=15;AN=2;AC=1 GT:GQ:DP ./.:.:. ./.:.:. 0/1:158:15 ./.:.:. ./.:.:. 4 3258448 . TACACACAC T . PASS AN=8;AC=4 GT:GQ:DP 0/1:325:31 0/1:325:31 ./.:.:. 0/1:325:31 0/1:325:31 bcftools-1.21/test/merge.abc.3.out000066400000000000000000000124611467060157400167620ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##FORMAT= ##FILTER= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:B C D 1 3000150 . C T 59.2 PASS AN=10;AC=2 GT:GQ 0/1:245 0/1:245 0/0:. 0/0:. 0/0:. 1 3000151 . C T 59.2 PASS AN=10;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 0/0:.:. 0/0:.:. 0/0:.:. 1 3062915 idSNP G T,C,A 419 test;q20 TEST=5;STR=.;DP=14;DP4=3,6,9,12;INTA=2,1,.;AN=9;AC=2,2,1 GT:TT:GQ:DP:GL:STR 0/1:0,1,.:409:35:-20,-5,-20,-20,-5,-20,.,.,.,.:. 2:0,1,.:409:35:-20,-5,-20,.:. 0/3:.:376:14:-10,.,.,.,.,.,0,.,.,-10:ABC 0/2:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 0/1:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 1 3062915 id3D GTTT G 84.6 q10;q20 INDEL;STR=test;TXT=AA;DP=1013;DP4=6,7,8,9;AN=10;AC=5 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:376:14:-10,0,-10 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 id1D;id2D GTT GT,G 999 q20;q10 DP=14;DP4=2,4,6,8;AN=10;AC=1,2 GT:GQ:DP:GL:STR 0/0:.:.:.:. 0/0:.:.:.:. 0/1:376:14:-10,0,-10,.,.,.:DEF 0/2:409:35:-20,.,.,-5,.,-20:. 0/2:409:35:-20,.,.,-5,.,-20:. 1 3106154 . C T 999 PASS DP=15;AN=10;AC=1 GT:GQ:DP:GL 0/0:.:.:. 0/0:.:.:. 0/1:277:15:-10,0,-10 0/0:.:.:. 0/0:.:.:. 1 3106154 . CAAAA CA,C 342 PASS DP=15;AN=6;AC=2,1 GT:GQ:DP:GL 0/1:245:32:. 0/1:245:32:. 0/2:277:15:-10,.,.,0,.,-10 .:245:32:. ./.:245:32:. 1 3106154 . C CT 459 PASS AN=10;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/0:.:. 0/1:245:32 0/1:245:32 1 3157410 . G T 46.7 q10 AN=10;AC=4 GT:GQ:DP 0/0:.:. 0/0:.:. 0/0:.:. 1/1:21:21 1/1:21:21 1 3157410 . GAC GC,G 90.6 q10 DP=11;AN=10;AC=4,1 GT:GQ:DP 1/1:21:21 1/1:21:21 0/2:49:11 0/0:.:. 0/0:.:. 1 3162006 . GAA G,GA 238 PASS DP=19;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F;AN=10;AC=3,2 GT:GQ:DP 0/1:212:22 0/1:212:22 0/1:589:19 0/2:212:22 0/2:212:22 1 3177144 . G T 999 PASS DP=24;AN=10;AC=3 GT:GQ:DP 0/0:150:30 1/1:150:30 0/1:236:24 0/0:150:30 0/0:150:30 1 3177144 . GT G 999 PASS DP=24;AN=10;AC=1 GT:GQ:DP 0/0:150:30 0/0:150:30 0/1:236:24 0/0:.:. 0/0:.:. 1 3184885 . TAAAA TA,T 61.5 PASS DP=16;AN=10;AC=5,4 GT:GQ:DP 1/2:12:10 1/2:12:10 0/1:435:16 1/2:12:10 1/2:12:10 2 3188209 . GA G 41.5 . DP=15;AN=10;AC=1 GT:GQ:DP 0/0:.:. 0/0:.:. 0/1:162:15 0/0:.:. 0/0:.:. 2 3199812 . G GTT,GT 291 PASS AN=10;AC=4,4 GT:GQ:DP 1/2:322:26 1/2:322:26 0/0:.:. 1/2:322:26 1/2:322:26 3 3199812 . GA GTT,GT 17.5 PASS DP=19;AN=10;AC=1,1 GT:GQ:DP 0/0:.:. 0/0:.:. 1/2:188:19 0/0:.:. 0/0:.:. 3 3212016 . CTT C,CT 79 PASS AN=10;AC=4,4 GT:GQ:DP 1/2:91:26 1/2:91:26 0/0:.:. 1/2:91:26 1/2:91:26 4 3212016 . CTT C 999 q20 DP=15;AN=10;AC=1 GT:GQ:DP 0/0:.:. 0/0:.:. 0/1:158:15 0/0:.:. 0/0:.:. 4 3258448 . TACACACAC T . PASS AN=10;AC=4 GT:GQ:DP 0/1:325:31 0/1:325:31 0/0:.:. 0/1:325:31 0/1:325:31 bcftools-1.21/test/merge.abc.out000066400000000000000000000124431467060157400166210ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##FORMAT= ##FILTER= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:B C D 1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. ./.:. 1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 ./.:.:. ./.:.:. ./.:.:. 1 3062915 idSNP G T,C,A 419 test;q20 TEST=5;STR=.;DP=14;DP4=3,6,9,12;INTA=2,1,.;AN=9;AC=2,2,1 GT:TT:GQ:DP:GL:STR 0/1:0,1,.:409:35:-20,-5,-20,-20,-5,-20,.,.,.,.:. 2:0,1,.:409:35:-20,-5,-20,.:. 0/3:.:376:14:-10,.,.,.,.,.,0,.,.,-10:ABC 0/2:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 0/1:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 1 3062915 id3D GTTT G 84.6 q10;q20 INDEL;STR=test;TXT=AA;DP=1013;DP4=6,7,8,9;AN=10;AC=5 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:376:14:-10,0,-10 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 id1D;id2D GTT GT,G 999 q20;q10 DP=14;DP4=2,4,6,8;AN=6;AC=1,2 GT:GQ:DP:GL:STR ./.:.:.:.:. ./.:.:.:.:. 0/1:376:14:-10,0,-10,.,.,.:DEF 0/2:409:35:-20,.,.,-5,.,-20:. 0/2:409:35:-20,.,.,-5,.,-20:. 1 3106154 . C T 999 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL ./.:.:.:. ./.:.:.:. 0/1:277:15:-10,0,-10 ./.:.:.:. ./.:.:.:. 1 3106154 . CAAAA CA,C 342 PASS DP=15;AN=6;AC=2,1 GT:GQ:DP:GL 0/1:245:32:. 0/1:245:32:. 0/2:277:15:-10,.,.,0,.,-10 .:245:32:. ./.:245:32:. 1 3106154 . C CT 459 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. 0/1:245:32 0/1:245:32 1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP ./.:.:. ./.:.:. ./.:.:. 1/1:21:21 1/1:21:21 1 3157410 . GAC GC,G 90.6 q10 DP=11;AN=6;AC=4,1 GT:GQ:DP 1/1:21:21 1/1:21:21 0/2:49:11 ./.:.:. ./.:.:. 1 3162006 . GAA G,GA 238 PASS DP=19;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F;AN=10;AC=3,2 GT:GQ:DP 0/1:212:22 0/1:212:22 0/1:589:19 0/2:212:22 0/2:212:22 1 3177144 . G T 999 PASS DP=24;AN=10;AC=3 GT:GQ:DP 0/0:150:30 1/1:150:30 0/1:236:24 0/0:150:30 0/0:150:30 1 3177144 . GT G 999 PASS DP=24;AN=6;AC=1 GT:GQ:DP 0/0:150:30 0/0:150:30 0/1:236:24 ./.:.:. ./.:.:. 1 3184885 . TAAAA TA,T 61.5 PASS DP=16;AN=10;AC=5,4 GT:GQ:DP 1/2:12:10 1/2:12:10 0/1:435:16 1/2:12:10 1/2:12:10 2 3188209 . GA G 41.5 . DP=15;AN=2;AC=1 GT:GQ:DP ./.:.:. ./.:.:. 0/1:162:15 ./.:.:. ./.:.:. 2 3199812 . G GTT,GT 291 PASS AN=8;AC=4,4 GT:GQ:DP 1/2:322:26 1/2:322:26 ./.:.:. 1/2:322:26 1/2:322:26 3 3199812 . GA GTT,GT 17.5 PASS DP=19;AN=2;AC=1,1 GT:GQ:DP ./.:.:. ./.:.:. 1/2:188:19 ./.:.:. ./.:.:. 3 3212016 . CTT C,CT 79 PASS AN=8;AC=4,4 GT:GQ:DP 1/2:91:26 1/2:91:26 ./.:.:. 1/2:91:26 1/2:91:26 4 3212016 . CTT C 999 q20 DP=15;AN=2;AC=1 GT:GQ:DP ./.:.:. ./.:.:. 0/1:158:15 ./.:.:. ./.:.:. 4 3258448 . TACACACAC T . PASS AN=8;AC=4 GT:GQ:DP 0/1:325:31 0/1:325:31 ./.:.:. 0/1:325:31 0/1:325:31 bcftools-1.21/test/merge.b.vcf000066400000000000000000000063101467060157400162600ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B 1 3062915 idSNP G A 24.6 q20 DP=14;DP4=1,2,3,4;AN=2;STR=.;AC=1 GT:GQ:DP:STR:GL 0/1:376:14:ABC:-10,0,-10 1 3062915 id1D GTT GT 101 q20 DP=14;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL:STR 0/1:376:14:-10,0,-10:DEF 1 3062915 id3D GTTT G 84.6 q20 TXT=AA;DP=14;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:376:14:-10,0,-10 1 3106154 . C T 999 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL 0/1:277:15:-10,0,-10 1 3106154 . CAAAA C 15.4 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL 0/1:277:15:-10,0,-10 1 3157410 . GAC G 36.8 PASS DP=11;AN=2;AC=1 GT:GQ:DP 0/1:49:11 1 3162006 . GAA G 238 PASS DP=19;AN=2;AC=1;XRF=1e6,2e6;XRI=1111,2222;XRS=AAA,BBB;XAF=1e6;XAI=1111;XAS=AAA;XGF=1e6,2e6,3e6;XGI=1111,2222,3333;XGS=A,B,C GT:GQ:DP 0/1:589:19 1 3177144 . G T 999 PASS DP=24;AN=2;AC=1 GT:GQ:DP 0/1:236:24 1 3177144 . GT G 999 PASS DP=24;AN=2;AC=1 GT:GQ:DP 0/1:236:24 1 3184885 . TAAA T 25.8 PASS DP=16;AN=2;AC=1 GT:GQ:DP 0/1:435:16 2 3188209 . GA G 41.5 . DP=15;AN=2;AC=1 GT:GQ:DP 0/1:162:15 3 3199812 . GA GTT,GT 17.5 PASS DP=19;AN=2;AC=1,1 GT:GQ:DP 1/2:188:19 4 3212016 . CTT C 999 q20 DP=15;AN=2;AC=1 GT:GQ:DP 0/1:158:15 bcftools-1.21/test/merge.c.vcf000066400000000000000000000062721467060157400162700ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FORMAT= ##FILTER= ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D 1 3062915 id3D GTTT G 48.7 q10 TXT=BB;DP=999;DP4=4,3,2,1;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G C,T 419 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1;INTA=1,2 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:409:35:-20,-5,-20,-20,-5,-20 1 3062915 id2D GTT G 999 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3106154 . CAAA C 72.6 PASS AN=0;AC=0 GT:GQ:DP .:245:32 ./.:245:32 1 3106154 . C CT 459 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA GA 206 PASS AN=4;AC=2;XRF=1e6,5e5;XRI=1111,5555;XRS=AAA,DDD;XAF=5e5;XAI=5555;XAS=DDD;XGF=1e6,5e5,9e9;XGI=1111,5555,9999;XGS=A,E,F GT:GQ:DP 0/1:212:22 0/1:212:22 1 3177144 . G . 364 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 1 3184885 . TAAAA TA,T 8.42 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:10 2 3199812 . G GTT,GT 291 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 3 3212016 . CTT C,CT 52.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 4 3258448 . TACACACAC T . PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 bcftools-1.21/test/merge.gvcf.10.1.out000066400000000000000000000007441467060157400174000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b chr1 1 . A <*>,C . . 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DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 17 834 . G A 363.72 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AC=4;AN=6;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 17 1869 . A T 138.104 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 17 2041 . G A 447.444 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 17 2220 . G A 302.575 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 17 2564 . A G 232.697 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 17 3104 . C T 24.2837 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AC=1;AN=6;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0/0:0,12,144:4:0 0/1:59,0,93:5:2 17 3587 . G A 357.834 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AC=4;AN=6;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 17 3936 . A G 469.356 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=4;AN=6;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.2.out000066400000000000000000000125131467060157400166070ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 1 . A . . . END=301;MIN_DP=1 GT:DP ./.:5 ./.:1 ./.:3 17 302 . T TA 487.586 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 0/1:167,0,96:11:6 0/1:157,0,9:7:6 1/1:201,21,0:7:7 17 303 . G . . . END=827;MIN_DP=2 GT:DP 0/0:9 0/0:2 0/0:3 17 828 . T C 409.29 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 17 829 . T . . . END=833;MIN_DP=4 GT:DP 0/0:11 0/0:8 0/0:4 17 834 . G A 363.72 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AC=4;AN=6;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 17 835 . T . . . END=1664;MIN_DP=1 GT:DP 0/0:5 0/0:2 0/0:1 17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 17 1666 . G . . . END=1868;MIN_DP=0 GT:DP 0/0:6 0/0:0 0/0:1 17 1869 . A T 138.104 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 17 1870 . C . . . END=2040;MIN_DP=1 GT:DP 0/0:13 0/0:2 0/0:1 17 2041 . G A 447.444 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 17 2042 . G . . . END=2219;MIN_DP=1 GT:DP 0/0:8 0/0:1 0/0:3 17 2220 . G A 302.575 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 17 2221 . G . . . END=2563;MIN_DP=0 GT:DP 0/0:5 0/0:0 0/0:2 17 2564 . A G 232.697 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 17 2565 . A . . . END=3103;MIN_DP=0 GT:DP 0/0:6 0/0:0 0/0:1 17 3104 . C T 24.2837 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AC=1;AN=6;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0/0:0,12,144:4:0 0/1:59,0,93:5:2 17 3105 . T . . . END=3586;MIN_DP=2 GT:DP 0/0:5 0/0:2 0/0:3 17 3587 . G A 357.834 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AC=4;AN=6;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 17 3588 . A . . . END=3935;MIN_DP=2 GT:DP 0/0:10 0/0:2 0/0:3 17 3936 . A G 469.356 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=4;AN=6;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 17 3937 . C . . . END=4101;MIN_DP=0 GT:DP 0/0:1 0/0:0 0/0:0 bcftools-1.21/test/mpileup.2.samples000066400000000000000000000000361467060157400174410ustar00rootroot00000000000000HG00100 2 HG00101 1 HG00102 2 bcftools-1.21/test/mpileup.2.tab000066400000000000000000000001401467060157400165370ustar00rootroot00000000000000chr1 212740 A,G chr1 320055 A,G chr1 486173 A,T chr1 511277 A,G chr1 602567 A,G chr1 639707 T,A bcftools-1.21/test/mpileup.2.vcf000066400000000000000000000060671467060157400165650ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://test/mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 chr1 212740 . A G,<*> 0 . DP=73;I16=0,0,39,4,0,0,2743,192525,0,0,2580,154800,0,0,825,18621;QS=0,2,0;VDB=0.520868;SGB=-1.38232;MQSB=1;MQ0F=0 PL:DP:AD 255,72,0,255,72,255:24:0,24,0 255,57,0,255,57,255:19:0,19,0 chr1 320055 . A <*> 0 . DP=101;I16=52,9,0,0,4116,300666,0,0,3660,219600,0,0,1281,29849,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:AD 0,87,255:29:29,0 0,96,255:32:32,0 chr1 486173 . A T,<*> 0 . DP=13;I16=3,1,3,0,287,21853,246,20172,240,14400,180,10800,95,2275,75,1875;QS=1.25,0.75,0;VDB=0.074936;SGB=0.620439;RPB=0.810265;MQB=1.01283;MQSB=1;BQB=0.810265;MQ0F=0 PL:DP:AD 0,9,151,9,151,151:3:3,0,0 140,0,48,143,57,194:4:1,3,0 chr1 511277 . A G,<*> 0 . DP=50;I16=0,0,25,4,0,0,1900,137374,0,0,1740,104400,0,0,672,16306;QS=0,2,0;VDB=0.0722735;SGB=-1.26186;MQSB=1;MQ0F=0 PL:DP:AD 255,30,0,255,30,255:10:0,10,0 255,57,0,255,57,255:19:0,19,0 chr1 602567 . A G,<*> 0 . DP=9;I16=3,1,1,0,328,26896,41,1681,240,14400,60,3600,99,2451,18,324;QS=1.81448,0.18552,0;SGB=-0.516033;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:AD 0,3,60,3,60,60:1:1,0,0 29,0,140,38,143,175:4:3,1,0 chr1 639707 . T A,<*> 0 . DP=50;I16=0,0,23,8,0,0,1998,142356,0,0,1860,111600,0,0,612,13818;QS=0,2,0;VDB=0.563111;SGB=-1.37269;MQSB=1;MQ0F=0 PL:DP:AD 255,42,0,255,42,255:14:0,14,0 255,51,0,255,51,255:17:0,17,0 bcftools-1.21/test/mpileup.3.out000066400000000000000000000106651467060157400166160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 302 . T TA 487.586 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 0/1:167,0,96:11:6 0/1:157,0,9:7:6 1/1:201,21,0:7:7 17 828 . T C 409.29 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 17 834 . G A 363.72 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AC=4;AN=6;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 17 1869 . A T 138.104 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 17 2041 . G A 447.444 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 17 2220 . G A 302.575 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 17 2564 . A G 232.697 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 17 3104 . C T 24.2837 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AC=1;AN=6;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0/0:0,12,144:4:0 0/1:59,0,93:5:2 17 3587 . G A 357.834 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AC=4;AN=6;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 17 3936 . A G 469.356 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=4;AN=6;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.3.samples000066400000000000000000000000301467060157400174340ustar00rootroot00000000000000HG00100 HG00101 HG00102 bcftools-1.21/test/mpileup.3.tab000066400000000000000000000000641467060157400165450ustar00rootroot0000000000000020 69066 C,G 20 69093 G,A 20 69094 G,A 20 69408 C,T bcftools-1.21/test/mpileup.3.vcf000066400000000000000000000630741467060157400165670ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 68813 . G <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68814 . G <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 68815 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68816 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,24 20 68817 . C <*> 0 . DP=1;I16=1,0,0,0,25,625,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,25 20 68818 . T <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68819 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68820 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68821 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68822 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68823 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68824 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68825 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68826 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68827 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68828 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68829 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68830 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68831 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68832 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68833 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68834 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68835 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68836 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68837 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68838 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68839 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68840 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68841 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68842 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68843 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68844 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68845 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68846 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68847 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68848 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68849 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68850 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68851 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68852 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,24 20 68853 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68854 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68855 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68856 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68857 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68858 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68859 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68860 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68861 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68862 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68863 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68864 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68865 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68866 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68867 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68868 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68869 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68870 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68871 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68872 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68873 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68874 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68875 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68876 . G <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68877 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68878 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68879 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68880 . T <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68881 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68882 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68883 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68884 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68885 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68886 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68887 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68888 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68889 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68890 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68891 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68892 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68893 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68894 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68895 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68896 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68897 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68898 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68899 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68900 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68901 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68902 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68903 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68904 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68905 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68906 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68907 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68908 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68909 . T <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68910 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68911 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68912 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68913 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68914 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68915 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68916 . G <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68917 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68918 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68919 . G <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68920 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68921 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68922 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68923 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68924 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68925 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68926 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68927 . A <*> 0 . DP=2;I16=1,0,0,0,58,3364,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,58 20 68928 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68929 . G <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68930 . T <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68931 . G <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,56 20 68932 . G <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68933 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68934 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68935 . T <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68936 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68937 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68938 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68939 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68940 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68941 . C <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68942 . A <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68943 . G <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,56 20 68944 . G <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68945 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68946 . T <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68947 . A <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68948 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68949 . A <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68950 . C <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68951 . A <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68952 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68953 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68954 . C <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68955 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68956 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68957 . G <*> 0 . DP=2;I16=1,0,0,0,55,3025,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,55 20 68958 . T <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68959 . G <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68960 . A <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,59 20 68961 . C <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,56 20 68962 . C <*> 0 . DP=2;I16=1,0,0,0,52,2704,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,52 20 68963 . A <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,59 20 68964 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68965 . T <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 20 68966 . G <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 20 68967 . G <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 20 68968 . G <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 20 68969 . G <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68970 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68971 . G <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68972 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68973 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68974 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68975 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68976 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68977 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68978 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68979 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68980 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68981 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68982 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68983 . A <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68984 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68985 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68986 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68987 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68988 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68989 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68990 . T <*> 0 . DP=1;I16=0,1,0,0,26,676,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,26 20 68991 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68992 . G <*> 0 . DP=1;I16=0,1,0,0,20,400,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,20 20 68993 . G <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68994 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68995 . A <*> 0 . DP=1;I16=0,1,0,0,25,625,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,25 20 68996 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68997 . A <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68998 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68999 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69000 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69001 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69002 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69003 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69004 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69005 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69006 . C <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 69007 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69008 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69009 . C <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 69010 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69011 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69012 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69013 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69014 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69015 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69016 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69017 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69018 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69019 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69020 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69021 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69022 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69023 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69024 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69025 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69026 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69027 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69028 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69029 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69030 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69031 . A <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 69032 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69033 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69034 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69035 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69036 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69037 . G <*> 0 . DP=1;I16=0,1,0,0,17,289,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,17 20 69038 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69039 . T <*> 0 . DP=1;I16=0,1,0,0,25,625,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,25 20 69040 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69041 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 69042 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69043 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69044 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69045 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69046 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69047 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69048 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69049 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69050 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69051 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69052 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69053 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69054 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69055 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69056 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69057 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69058 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69059 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69060 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69061 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 69062 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69063 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69064 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69065 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69066 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69067 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69068 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69069 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69070 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69071 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69072 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69073 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69074 . T <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69075 . T <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 69076 . A <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,28 bcftools-1.21/test/mpileup.4.out000066400000000000000000000106651467060157400166170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00102 HG00101 HG00100 17 302 . T TA 487.586 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 1/1:201,21,0:7:7 0/1:157,0,9:7:6 0/1:167,0,96:11:6 17 828 . T C 409.29 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 1/1:120,12,0:4:4 0/1:116,0,91:9:5 0/1:211,0,35:12:10 17 834 . G A 363.72 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AC=4;AN=6;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 1/1:89,9,0:3:3 0/1:128,0,59:8:5 0/1:185,0,46:11:9 17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/1:35,0,51:4:2 0/0:0,27,222:9:0 0/0:0,21,185:7:0 17 1869 . A T 138.104 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 1/1:42,3,0:1:1 0/1:16,0,104:5:1 0/1:115,0,224:18:7 17 2041 . G A 447.444 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 1/1:223,21,0:7:7 0/1:32,0,24:2:1 0/1:229,0,212:21:11 17 2220 . G A 302.575 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 1/1:131,12,0:4:4 0/1:69,0,46:4:2 0/1:139,0,130:12:6 17 2564 . A G 232.697 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 1/1:124,12,0:4:4 0/1:57,0,56:4:2 0/1:88,0,78:6:3 17 3104 . C T 24.2837 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AC=1;AN=6;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/1:59,0,93:5:2 0/0:0,12,144:4:0 0/0:0,48,255:16:0 17 3587 . G A 357.834 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AC=4;AN=6;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 1/1:212,24,0:8:8 0/1:22,0,118:5:1 0/1:161,0,184:14:7 17 3936 . A G 469.356 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=4;AN=6;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 1/1:196,24,0:8:8 0/1:77,0,58:6:4 0/1:233,0,206:20:11 bcftools-1.21/test/mpileup.4.samples000066400000000000000000000000301467060157400174350ustar00rootroot00000000000000HG00102 HG00101 HG00100 bcftools-1.21/test/mpileup.4.tab000066400000000000000000000001011467060157400165360ustar00rootroot0000000000000020 69066 C,G 20 69076 A,G 20 69093 G,A 20 69094 G,A 20 69408 C,T bcftools-1.21/test/mpileup.4.vcf000066400000000000000000000211401467060157400165540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##contig= ##contig= ##contig= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 1368813 . G <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 1368814 . G <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,28 1 1368815 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 1368816 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,24 1 1368817 . C <*> 0 . DP=1;I16=1,0,0,0,25,625,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,25 1 1368818 . T <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368819 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368820 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368821 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368822 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 1368823 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 1368824 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 1368825 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368826 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368827 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 1368828 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368829 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 1368830 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 1368831 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 1368832 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 1368833 . T <*> 0 . DP=1;I16=0,1,0,0,13,169,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,13 1 1368833 . TAAAAAAAAAAAAAAAA TAAAAAAAAAAAAAA 0 . DP=2;I16=0,1,1,0,10,100,30,900,60,3600,60,3600,3,9,25,625;QS=0.5,0.5 PL 6,0,6 1 1368834 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 1368835 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68836 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68837 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68838 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68839 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68840 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68841 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68842 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68843 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68844 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68845 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68846 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68847 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68848 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68849 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68850 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68851 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68852 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,24 20 68853 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68854 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68855 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68856 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68857 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68858 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68859 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68860 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68861 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69045 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69046 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69047 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69048 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69049 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69050 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69051 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69052 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69053 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69054 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69055 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,30 21 69056 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,32 21 69057 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,32 21 69058 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,30 21 69059 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,32 21 69060 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,32 21 69061 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,29 21 69062 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,33 21 69063 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,31 21 69064 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,33 21 69065 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,33 21 69066 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,33 21 69067 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,30 21 69068 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,32 21 69069 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,31 21 69070 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,33 21 69071 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,33 21 69072 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,30 21 69073 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,30 21 69074 . T <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,30 21 69075 . T <*> 0 . 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DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=3;AN=4;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 1/1:131,12,0:4:4 0/1:69,0,46:4:2 17 2564 . A G 147.291 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=3;AN=4;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 1/1:124,12,0:4:4 0/1:57,0,56:4:2 17 3104 . C T 24.6136 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AC=1;AN=4;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/1:59,0,93:5:2 0/0:0,12,144:4:0 17 3587 . G A 198.948 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AC=3;AN=4;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 1/1:212,24,0:8:8 0/1:22,0,118:5:1 17 3936 . A G 239.224 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=3;AN=4;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 1/1:196,24,0:8:8 0/1:77,0,58:6:4 bcftools-1.21/test/mpileup.5.samples000066400000000000000000000000201467060157400174350ustar00rootroot00000000000000HG00102 HG00101 bcftools-1.21/test/mpileup.5.tab000066400000000000000000000001161467060157400165450ustar00rootroot0000000000000020 68799 T,C 20 68800 A,G 20 68810 G,A 20 69066 C,G 20 69094 G,A 20 69408 C,T bcftools-1.21/test/mpileup.5.vcf000066400000000000000000001525671467060157400165770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///hs37d5.fa ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 116844232 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,24 1 116844233 . A <*> 0 . DP=1;I16=1,0,0,0,27,729,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,27 1 116844234 . A <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,26 1 116844235 . G <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844236 . T <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,26 1 116844237 . A <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,26 1 116844238 . G <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844239 . C <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844240 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844241 . A <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,28 1 116844242 . A <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,28 1 116844243 . A <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,28 1 116844244 . C <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844245 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844246 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844247 . T <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844248 . G <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844249 . T <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,28 1 116844250 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844251 . T <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844252 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844253 . T <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844254 . A <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,28 1 116844255 . C <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844256 . T <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844257 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844258 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844259 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844260 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844261 . A <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844262 . T <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844263 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844264 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844265 . A <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844266 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844267 . A <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844268 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844269 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844270 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844271 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844272 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844273 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844274 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844275 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844276 . A <*> 0 . DP=2;I16=1,0,0,0,14,196,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,14 1 116844276 . AAAGAA AAA 0 . INDEL;IDV=1;IMF=0.5;DP=2;I16=0,1,1,0,10,100,71,5041,60,3600,60,3600,0,0,25,625;QS=0.117647,0.882353;VDB=0.5;SGB=-0.379885;MQSB=1;MQ0F=0 PL 25,1,0 1 116844277 . A <*> 0 . DP=1;I16=0,1,0,0,14,196,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,14 1 116844278 . A <*> 0 . DP=1;I16=0,1,0,0,14,196,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,14 1 116844279 . G <*> 0 . DP=1;I16=0,1,0,0,13,169,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,13 1 116844279 . GAAAAAAAAAAAAAAAA GAAAAAAAAAAAAAA 0 . INDEL;IDV=1;IMF=0.5;DP=2;I16=0,1,1,0,10,100,30,900,60,3600,60,3600,3,9,25,625;QS=0.5,0.5;VDB=0.5;SGB=-0.379885;MQSB=1;MQ0F=0 PL 6,0,6 1 116844280 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844281 . A <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844282 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844283 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844284 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844285 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844286 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844287 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844288 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844289 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844290 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844291 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844292 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844293 . A <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 1 116844294 . A <*> 0 . DP=2;I16=1,0,0,0,18,324,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,18 1 116844295 . A <*> 0 . DP=2;I16=1,0,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 1 116844296 . G <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844297 . C <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844298 . C <*> 0 . DP=2;I16=1,0,0,0,52,2704,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 1 116844299 . G <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844300 . G <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844301 . A <*> 0 . DP=2;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 1 116844302 . T <*> 0 . DP=2;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844303 . A <*> 0 . DP=2;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 1 116844304 . T <*> 0 . DP=2;I16=1,0,0,0,52,2704,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 1 116844305 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844306 . G <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844307 . T <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844308 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844309 . G <*> 0 . DP=2;I16=1,0,0,0,46,2116,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,46 1 116844310 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844311 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844312 . C <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844313 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844314 . T <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844315 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844316 . C <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844317 . C <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844318 . T <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844319 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844320 . T <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844321 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844322 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844323 . T <*> 0 . DP=2;I16=1,0,0,0,17,289,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,17 1 116844324 . C <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844325 . C <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844326 . C <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844327 . A <*> 0 . DP=2;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 1 116844328 . G <*> 0 . DP=2;I16=1,0,0,0,68,4624,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844329 . C <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844330 . T <*> 0 . DP=2;I16=1,0,0,0,58,3364,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,58 1 116844331 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844332 . C <*> 0 . DP=2;I16=1,0,0,0,45,2025,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,45 1 116844333 . T <*> 0 . DP=2;I16=1,0,0,0,49,2401,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,49 1 116844334 . C <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844335 . G <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844336 . G <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844337 . G <*> 0 . DP=2;I16=1,0,0,0,55,3025,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,55 1 116844338 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844339 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844340 . G <*> 0 . DP=2;I16=1,0,0,0,51,2601,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,51 1 116844341 . C <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844342 . T <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844343 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844344 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844345 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844346 . G <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844347 . T <*> 0 . DP=2;I16=1,0,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 1 116844348 . G <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844349 . G <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844350 . G <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844351 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844352 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844353 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844354 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844355 . T <*> 0 . DP=2;I16=1,0,0,0,49,2401,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,49 1 116844356 . C <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844357 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844358 . C <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844359 . C <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844360 . T <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844361 . G <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844362 . A <*> 0 . DP=2;I16=1,0,0,0,55,3025,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,55 1 116844363 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844364 . C <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844365 . C <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844366 . A <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844367 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844368 . G <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844369 . G <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,54 1 116844370 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844371 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844372 . G <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,53 1 116844373 . T <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,56 1 116844374 . C <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844375 . G <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844376 . A <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,56 1 116844377 . G <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844378 . T <*> 0 . DP=2;I16=0,1,0,0,26,676,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,26 1 116844379 . C <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844380 . T <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844381 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844382 . C <*> 0 . DP=2;I16=1,0,0,0,52,2704,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,52 1 116844383 . C <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,59 1 116844384 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,60 1 116844385 . T <*> 0 . DP=2;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844386 . G <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844387 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844388 . A <*> 0 . DP=1;I16=0,1,0,0,26,676,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,26 1 116844389 . C <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 1 116844390 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844391 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844392 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844393 . G <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844394 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844395 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844396 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844397 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844398 . A <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844399 . G <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844400 . C <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 1 116844401 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844402 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844403 . C <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844404 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844405 . G <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844406 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844407 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844408 . C <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844409 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844410 . C <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,22 1 116844411 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844412 . A <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844413 . G <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844414 . C <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,22 1 116844415 . C <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844416 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844417 . G <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844418 . G <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844419 . G <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,35 1 116844420 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,34 1 116844421 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,31 1 116844422 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844423 . C <*> 0 . DP=1;I16=0,1,0,0,20,400,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,20 1 116844424 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,33 1 116844425 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,30 1 116844426 . G <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,32 1 116844427 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,29 1 116844428 . G <*> 0 . DP=1;I16=0,1,0,0,27,729,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,27 20 68813 . G <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68814 . G <*> 0 . DP=1;I16=1,0,0,0,28,784,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 68815 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68816 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,24 20 68817 . C <*> 0 . DP=1;I16=1,0,0,0,25,625,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,25 20 68818 . T <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68819 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68820 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68821 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68822 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68823 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68824 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68825 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68826 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68827 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68828 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68829 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68830 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68831 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68832 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68833 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68834 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68835 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68836 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68837 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68838 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68839 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68840 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68841 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68842 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68843 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68844 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68845 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68846 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68847 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68848 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68849 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68850 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68851 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68852 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,24 20 68853 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68854 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68855 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68856 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68857 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68858 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68859 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68860 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68861 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68862 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68863 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68864 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68865 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68866 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68867 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68868 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68869 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68870 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68871 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68872 . T <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68873 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68874 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68875 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68876 . G <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68877 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68878 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68879 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68880 . T <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68881 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68882 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68883 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68884 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68885 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68886 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68887 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68888 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68889 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68890 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68891 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68892 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68893 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68894 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68895 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68896 . C <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68897 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68898 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68899 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68900 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68901 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68902 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68903 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68904 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68905 . T <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68906 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68907 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68908 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68909 . T <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68910 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68911 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68912 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68913 . G <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68914 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68915 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68916 . G <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68917 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68918 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68919 . G <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68920 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68921 . G <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 68922 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68923 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68924 . A <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68925 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 20 68926 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68927 . A <*> 0 . DP=2;I16=1,0,0,0,58,3364,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,58 20 68928 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68929 . G <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68930 . T <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68931 . G <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,56 20 68932 . G <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68933 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68934 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68935 . T <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68936 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68937 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68938 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68939 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68940 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68941 . C <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68942 . A <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68943 . G <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,56 20 68944 . G <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68945 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68946 . T <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68947 . A <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68948 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68949 . A <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68950 . C <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68951 . A <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68952 . G <*> 0 . DP=2;I16=1,0,0,0,67,4489,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68953 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68954 . C <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68955 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68956 . A <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68957 . G <*> 0 . DP=2;I16=1,0,0,0,55,3025,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,55 20 68958 . T <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68959 . G <*> 0 . DP=2;I16=1,0,0,0,64,4096,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,60 20 68960 . A <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,59 20 68961 . C <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,56 20 68962 . C <*> 0 . DP=2;I16=1,0,0,0,52,2704,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,52 20 68963 . A <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,59 20 68964 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68965 . T <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 20 68966 . G <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 20 68967 . G <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 20 68968 . G <*> 0 . DP=1;I16=0,1,0,0,22,484,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,22 20 68969 . G <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68970 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68971 . G <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68972 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68973 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68974 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68975 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68976 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68977 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68978 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68979 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68980 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68981 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68982 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68983 . A <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68984 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68985 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 68986 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68987 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68988 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 68989 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68990 . T <*> 0 . DP=1;I16=0,1,0,0,26,676,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,26 20 68991 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68992 . G <*> 0 . DP=1;I16=0,1,0,0,20,400,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,20 20 68993 . G <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 68994 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 68995 . A <*> 0 . DP=1;I16=0,1,0,0,25,625,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,25 20 68996 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68997 . A <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68998 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 68999 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69000 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69001 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69002 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69003 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69004 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69005 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69006 . C <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 69007 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69008 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69009 . C <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 20 69010 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69011 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69012 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69013 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69014 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69015 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69016 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69017 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69018 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69019 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69020 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69021 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69022 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69023 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69024 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69025 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69026 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69027 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69028 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69029 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69030 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69031 . A <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 69032 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69033 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69034 . A <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69035 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69036 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69037 . G <*> 0 . DP=1;I16=0,1,0,0,17,289,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,17 20 69038 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69039 . T <*> 0 . DP=1;I16=0,1,0,0,25,625,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,25 20 69040 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69041 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 69042 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69043 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69044 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69045 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69046 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69047 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69048 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69049 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69050 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69051 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69052 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69053 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69054 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69055 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69056 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69057 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69058 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69059 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69060 . T <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69061 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,29 20 69062 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69063 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69064 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69065 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69066 . C <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69067 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69068 . A <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,32 20 69069 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,31 20 69070 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69071 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,33 20 69072 . A <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69073 . C <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69074 . T <*> 0 . DP=1;I16=0,1,0,0,30,900,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,30 20 69075 . T <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,28 20 69076 . A <*> 0 . DP=1;I16=0,1,0,0,28,784,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,28 21 9412423 . A <*> 0 . DP=2;I16=1,0,0,0,56,3136,0,0,52,2704,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412424 . T <*> 0 . DP=2;I16=1,0,0,0,58,3364,0,0,52,2704,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412425 . A <*> 0 . DP=2;I16=1,0,0,0,57,3249,0,0,52,2704,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412426 . A <*> 0 . DP=2;I16=1,0,0,0,58,3364,0,0,52,2704,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412427 . T <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412428 . T <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,52,2704,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412429 . C <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,52,2704,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412430 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,52,2704,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412431 . G <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,52,2704,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412432 . T <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,52,2704,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412433 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412434 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412435 . T <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,52,2704,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412436 . G <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,52,2704,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412437 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412438 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,52,2704,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412439 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412440 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412441 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412442 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,52,2704,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412443 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412444 . A <*> 0 . DP=2;I16=1,0,0,0,55,3025,0,0,52,2704,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412445 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412446 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412447 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412448 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412449 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412450 . A <*> 0 . DP=2;I16=1,0,0,0,51,2601,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,51 21 9412451 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412452 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412453 . A <*> 0 . DP=2;I16=1,0,0,0,54,2916,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412454 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412455 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412456 . T <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412457 . A <*> 0 . DP=2;I16=1,0,0,0,51,2601,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,51 21 9412458 . T <*> 0 . DP=2;I16=1,0,0,0,57,3249,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412459 . G <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412460 . T <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412461 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412462 . A <*> 0 . DP=2;I16=1,0,0,0,36,1296,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 21 9412463 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412464 . A <*> 0 . DP=2;I16=1,0,0,0,51,2601,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,51 21 9412465 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412466 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412467 . A <*> 0 . DP=2;I16=1,0,0,0,42,1764,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 21 9412468 . G <*> 0 . DP=2;I16=1,0,0,0,66,4356,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412469 . G <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412470 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,52,2704,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412471 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412472 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412473 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412474 . A <*> 0 . DP=2;I16=1,0,0,0,42,1764,0,0,52,2704,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,42 21 9412475 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412476 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412477 . A <*> 0 . DP=2;I16=1,0,0,0,62,3844,0,0,52,2704,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412478 . T <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412479 . A <*> 0 . DP=2;I16=1,0,0,0,51,2601,0,0,52,2704,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,51 21 9412480 . A <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412481 . G <*> 0 . DP=2;I16=1,0,0,0,68,4624,0,0,52,2704,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412482 . A <*> 0 . DP=2;I16=1,0,0,0,55,3025,0,0,52,2704,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412483 . T <*> 0 . DP=2;I16=1,0,0,0,61,3721,0,0,52,2704,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412484 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412485 . C <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,52,2704,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412486 . A <*> 0 . DP=2;I16=1,0,0,0,63,3969,0,0,52,2704,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412487 . A <*> 0 . DP=2;I16=1,0,0,0,59,3481,0,0,52,2704,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412488 . A <*> 0 . DP=2;I16=1,0,0,0,60,3600,0,0,52,2704,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412489 . A <*> 0 . DP=2;I16=1,0,0,0,49,2401,0,0,52,2704,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,3,49 21 9412490 . A <*> 0 . DP=2;I16=1,0,0,0,53,2809,0,0,52,2704,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412491 . G <*> 0 . DP=2;I16=1,0,0,0,65,4225,0,0,52,2704,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412492 . T <*> 0 . DP=2;I16=1,0,0,0,57,3249,0,0,52,2704,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412493 . A <*> 0 . DP=2;I16=1,0,0,0,35,1225,0,0,52,2704,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,35 21 9412494 . A <*> 0 . DP=2;I16=1,0,0,0,57,3249,0,0,52,2704,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,52 21 9412495 . G <*> 0 . 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DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=4;AN=5;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 1:77,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.X.out000066400000000000000000000106171467060157400166600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 X 302 . T TA 482.1 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AC=4;AN=5;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 0/1:167,0,96:11:6 1:157,9:7:6 1/1:201,21,0:7:7 X 828 . T C 322.296 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AC=4;AN=5;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 1:116,91:9:5 1/1:120,12,0:4:4 X 834 . G A 309.32 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AC=4;AN=5;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 1:128,59:8:5 1/1:89,9,0:3:3 X 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 X 1869 . A T 138.104 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 X 2041 . G A 447.444 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 X 2220 . G A 302.575 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 X 2564 . A G 232.697 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 X 3104 . C T 24.8375 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AC=1;AN=5;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 X 3587 . G A 335.348 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AC=3;AN=5;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 X 3936 . A G 413.695 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AC=4;AN=5;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 1:77,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.X.vcf000066400000000000000000023504331467060157400166340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 X 1 . A <*> 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 2 . A <*> 0 . DP=11;I16=11,0,0,0,439,17587,0,0,319,9251,0,0,226,5030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 3 . G <*> 0 . DP=11;I16=11,0,0,0,431,16971,0,0,319,9251,0,0,229,5111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 4 . C <*> 0 . DP=11;I16=11,0,0,0,423,16417,0,0,319,9251,0,0,232,5202,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,71:3:0 X 5 . T <*> 0 . DP=11;I16=11,0,0,0,450,18520,0,0,319,9251,0,0,234,5252,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 6 . T <*> 0 . DP=11;I16=11,0,0,0,403,14847,0,0,319,9251,0,0,236,5310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 7 . C <*> 0 . DP=11;I16=11,0,0,0,446,18114,0,0,319,9251,0,0,237,5327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 8 . T <*> 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 9 . C <*> 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 10 . A <*> 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 X 11 . C <*> 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 12 . C <*> 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 13 . C <*> 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 14 . T <*> 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 15 . G <*> 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 16 . T <*> 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 17 . T <*> 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 18 . C <*> 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 X 19 . C <*> 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 X 20 . T <*> 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 X 21 . G <*> 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 X 22 . C <*> 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 X 23 . A <*> 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 X 24 . T <*> 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 X 25 . A <*> 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 X 26 . G <*> 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 X 27 . A <*> 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 X 28 . T <*> 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 X 29 . A <*> 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 X 30 . A <*> 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 X 31 . T <*> 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 X 32 . T <*> 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 X 33 . G <*> 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 X 34 . C <*> 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 X 35 . A <*> 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 X 36 . T <*> 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 X 37 . G <*> 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 X 38 . A <*> 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 X 39 . C <*> 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 X 40 . A <*> 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 X 41 . A <*> 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 X 42 . T <*> 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 X 43 . T <*> 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 X 44 . G <*> 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 X 45 . C <*> 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 X 46 . C <*> 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 X 47 . T <*> 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 X 48 . T <*> 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 X 49 . G <*> 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 X 50 . T <*> 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 X 51 . C <*> 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 X 52 . C <*> 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 X 53 . C <*> 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 X 54 . T <*> 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 X 55 . G <*> 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 X 56 . C <*> 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 X 57 . T <*> 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 X 58 . G <*> 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 X 59 . A <*> 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 X 60 . A <*> 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 X 61 . T <*> 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 X 62 . G <*> 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 X 63 . T <*> 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 X 64 . G <*> 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 X 65 . C <*> 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 X 66 . T <*> 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 X 67 . C <*> 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 X 68 . T <*> 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 X 69 . G <*> 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 X 70 . G <*> 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 X 71 . G <*> 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 X 72 . G <*> 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 X 73 . T <*> 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 X 74 . C <*> 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 X 75 . T <*> 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 X 76 . C <*> 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 X 77 . T <*> 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 X 78 . G <*> 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 X 79 . G <*> 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 X 80 . G <*> 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 X 81 . G <*> 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 X 82 . T <*> 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 X 83 . C <*> 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 X 84 . T <*> 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 X 85 . C <*> 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 X 86 . A <*> 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 X 87 . C <*> 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 X 88 . C <*> 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 X 89 . C <*> 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 X 90 . A <*> 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 X 91 . C <*> 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 X 92 . G <*> 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 X 93 . A <*> 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 X 94 . C <*> 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 X 95 . C <*> 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 X 96 . A <*> 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 X 97 . A <*> 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 X 98 . C <*> 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 X 99 . T <*> 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 X 100 . C <*> 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 X 101 . C <*> 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 X 102 . C <*> 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 X 103 . T <*> 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 X 104 . G <*> 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 X 105 . G <*> 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 X 106 . G <*> 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 X 107 . C <*> 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 X 108 . C <*> 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 X 109 . T <*> 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 X 110 . G <*> 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 X 111 . G <*> 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 X 112 . C <*> 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 X 113 . A <*> 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 X 114 . C <*> 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 X 115 . C <*> 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 X 116 . A <*> 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 X 117 . G <*> 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 X 118 . G <*> 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 X 119 . G <*> 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 X 120 . A <*> 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 X 121 . G <*> 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 X 122 . C <*> 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 X 123 . T <*> 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 X 124 . T <*> 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 X 125 . A <*> 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 X 126 . A <*> 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 X 127 . C <*> 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 X 128 . A <*> 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 X 129 . A <*> 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 X 130 . A <*> 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 X 131 . C <*> 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 X 132 . A <*> 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 X 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 X 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 X 135 . T <*> 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 X 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 X 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 X 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 X 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 X 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 X 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 X 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 X 143 . G <*> 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 X 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 X 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 X 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 X 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 X 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 X 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 X 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 X 151 . G <*> 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 X 152 . C <*> 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 X 153 . A <*> 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 X 154 . T <*> 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 X 155 . C <*> 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 X 156 . C <*> 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 X 157 . C <*> 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 X 158 . T <*> 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 X 159 . A <*> 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 X 160 . G <*> 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 X 161 . A <*> 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 X 162 . A <*> 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 X 163 . G <*> 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 X 164 . T <*> 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 X 165 . G <*> 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 X 166 . A <*> 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 X 167 . A <*> 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 X 168 . G <*> 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 X 169 . C <*> 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 X 170 . C <*> 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 X 171 . A <*> 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 X 172 . C <*> 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 X 173 . C <*> 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 X 174 . G <*> 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 X 175 . C <*> 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 X 176 . C <*> 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 X 177 . C <*> 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 X 178 . A <*> 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 X 179 . A <*> 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 X 180 . A <*> 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 X 181 . G <*> 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 X 182 . A <*> 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 X 183 . C <*> 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 X 184 . A <*> 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 X 185 . C <*> 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 X 186 . G <*> 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 X 187 . C <*> 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 X 188 . C <*> 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 X 189 . C <*> 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 X 190 . A <*> 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 X 191 . T <*> 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 X 192 . G <*> 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 X 193 . T <*> 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 X 194 . C <*> 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 X 195 . C <*> 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 X 196 . A <*> 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 X 197 . G <*> 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 X 198 . C <*> 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 X 199 . T <*> 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 X 200 . T <*> 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 X 201 . A <*> 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 X 202 . A <*> 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 X 203 . C <*> 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 X 204 . C <*> 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 X 205 . T <*> 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 X 206 . G <*> 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 X 207 . C <*> 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 X 208 . A <*> 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 X 209 . T <*> 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 X 210 . C <*> 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 X 211 . C <*> 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 X 212 . C <*> 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 X 213 . T <*> 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 X 214 . A <*> 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 X 215 . G <*> 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 X 216 . A <*> 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 X 217 . A <*> 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 X 218 . G <*> 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 X 219 . T <*> 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 X 220 . G <*> 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 X 221 . A <*> 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 X 222 . A <*> 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 X 223 . G <*> 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 X 224 . G <*> 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 X 225 . C <*> 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 X 226 . A <*> 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 X 227 . C <*> 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 X 228 . C <*> 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 X 229 . G <*> 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 X 230 . C <*> 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 X 231 . C <*> 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 X 232 . C <*> 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 X 233 . A <*> 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 X 234 . A <*> 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 X 235 . A <*> 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 X 236 . G <*> 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 X 237 . A <*> 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 X 238 . C <*> 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 X 239 . A <*> 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 X 240 . C <*> 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 X 241 . G <*> 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 X 242 . C <*> 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 X 243 . C <*> 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 X 244 . C <*> 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 X 245 . A <*> 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 X 246 . T <*> 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 X 247 . G <*> 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 X 248 . T <*> 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 X 249 . C <*> 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 X 250 . C <*> 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 X 251 . A <*> 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 X 252 . G <*> 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 X 253 . C <*> 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 X 254 . T <*> 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 X 255 . T <*> 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 X 256 . A <*> 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 X 257 . T <*> 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 X 258 . T <*> 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 X 259 . C <*> 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 X 260 . T <*> 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 X 261 . G <*> 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 X 262 . C <*> 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 X 263 . C <*> 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 X 264 . C <*> 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 X 265 . A <*> 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 X 266 . G <*> 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 X 267 . T <*> 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 X 268 . T <*> 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 X 269 . C <*> 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 X 270 . C <*> 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 X 271 . T <*> 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 X 272 . C <*> 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 X 273 . T <*> 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 X 274 . C <*> 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 X 275 . C <*> 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 X 276 . A <*> 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 X 277 . G <*> 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 X 278 . A <*> 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 X 279 . A <*> 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 X 280 . A <*> 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 X 281 . G <*> 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 X 282 . G <*> 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 X 283 . C <*> 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 X 284 . T <*> 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 X 285 . G <*> 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 X 286 . C <*> 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 X 287 . A <*> 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 X 288 . T <*> 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 X 289 . G <*> 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 X 290 . G <*> 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 X 291 . T <*> 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 X 292 . T <*> 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 X 293 . G <*> 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 X 294 . A <*> 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 X 295 . C <*> 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 X 296 . A <*> 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 X 297 . C <*> 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 X 298 . A <*> 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 X 299 . C <*> 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 X 300 . A <*> 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 X 301 . G <*> 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 X 302 . T <*> 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 X 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 X 303 . G <*> 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 X 304 . C <*> 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 X 305 . C <*> 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 X 306 . T <*> 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 X 307 . G <*> 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 X 308 . C <*> 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 X 309 . G <*> 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 X 310 . A <*> 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 X 311 . C <*> 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 X 312 . A <*> 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 X 313 . A <*> 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 X 314 . A <*> 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 X 315 . G <*> 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 X 316 . C <*> 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 X 317 . T <*> 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 X 318 . G <*> 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 X 319 . A <*> 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 X 320 . A <*> 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 X 321 . T <*> 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 X 322 . G <*> 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 X 323 . C <*> 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 X 324 . T <*> 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 X 325 . A <*> 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 X 326 . T <*> 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 X 327 . C <*> 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 X 328 . A <*> 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 X 329 . T <*> 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 X 330 . T <*> 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 X 331 . T <*> 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 X 332 . A <*> 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 X 333 . A <*> 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 X 334 . A <*> 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 X 335 . A <*> 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 X 336 . A <*> 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 X 337 . C <*> 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 X 338 . T <*> 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 X 339 . C <*> 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 X 340 . C <*> 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 X 341 . T <*> 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 X 342 . T <*> 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 X 343 . G <*> 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 X 344 . C <*> 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 X 345 . T <*> 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 X 346 . G <*> 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 X 347 . G <*> 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 X 348 . T <*> 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 X 349 . T <*> 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 X 350 . T <*> 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 X 351 . G <*> 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 X 352 . A <*> 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 X 353 . G <*> 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 X 354 . A <*> 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 X 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 X 356 . G <*> 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 X 357 . C <*> 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 X 358 . A <*> 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 X 359 . G <*> 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 X 360 . A <*> 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 X 361 . A <*> 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 X 362 . A <*> 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 X 363 . A <*> 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 X 364 . T <*> 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 X 365 . G <*> 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 X 366 . A <*> 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 X 367 . T <*> 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 X 368 . A <*> 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 X 369 . T <*> 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 X 370 . C <*> 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 X 371 . T <*> 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 X 372 . C <*> 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 X 373 . A <*> 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 X 374 . T <*> 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 X 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 X 376 . G <*> 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 X 377 . T <*> 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 X 378 . T <*> 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 X 379 . G <*> 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 X 380 . C <*> 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 X 381 . T <*> 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 X 382 . T <*> 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 X 383 . T <*> 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 X 384 . A <*> 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 X 385 . C <*> 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 X 386 . T <*> 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 X 387 . T <*> 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 X 388 . T <*> 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 X 389 . G <*> 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 X 390 . C <*> 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 X 391 . A <*> 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 X 392 . T <*> 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 X 393 . A <*> 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 X 394 . T <*> 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 X 395 . T <*> 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 X 396 . T <*> 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 X 397 . T <*> 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 X 398 . A <*> 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 X 399 . A <*> 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 X 400 . A <*> 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 X 401 . A <*> 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 X 402 . T <*> 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 X 403 . T <*> 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 X 404 . G <*> 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 X 405 . T <*> 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 X 406 . G <*> 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 X 407 . A <*> 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 X 408 . C <*> 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 X 409 . T <*> 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 X 410 . T <*> 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 X 411 . T <*> 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 X 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 X 413 . A <*> 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 X 414 . T <*> 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 X 415 . G <*> 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 X 416 . G <*> 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 X 417 . C <*> 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 X 418 . A <*> 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 X 419 . T <*> 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 X 420 . A <*> 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 X 421 . A <*> 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 X 422 . A <*> 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 X 423 . T <*> 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 X 424 . A <*> 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 X 425 . A <*> 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 X 426 . T <*> 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 X 427 . A <*> 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 X 428 . C <*> 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 X 429 . T <*> 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 X 430 . G <*> 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 X 431 . G <*> 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 X 432 . T <*> 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 X 433 . T <*> 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 X 434 . T <*> 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 X 435 . A <*> 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 X 436 . T <*> 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 X 437 . T <*> 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 X 438 . A <*> 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 X 439 . C <*> 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 X 440 . A <*> 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 X 441 . G <*> 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 X 442 . A <*> 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 X 443 . A <*> 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 X 444 . G <*> 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 X 445 . C <*> 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 X 446 . A <*> 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 X 447 . C <*> 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 X 448 . T <*> 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 X 449 . A <*> 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 X 450 . G <*> 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 X 451 . A <*> 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 X 452 . A <*> 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 X 453 . A <*> 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 X 454 . A <*> 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 X 455 . T <*> 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 X 456 . G <*> 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 X 457 . C <*> 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 X 458 . A <*> 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 X 459 . T <*> 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 X 460 . G <*> 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 X 461 . T <*> 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 X 462 . G <*> 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 X 463 . G <*> 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 X 464 . A <*> 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 X 465 . C <*> 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 X 466 . A <*> 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 X 467 . A <*> 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 X 468 . A <*> 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 X 469 . A <*> 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 X 470 . G <*> 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 X 471 . T <*> 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 X 472 . T <*> 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 X 473 . G <*> 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 X 474 . G <*> 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 X 475 . G <*> 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 X 476 . A <*> 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 X 477 . T <*> 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 X 478 . T <*> 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 X 479 . A <*> 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 X 480 . G <*> 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 X 481 . G <*> 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 X 482 . A <*> 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 X 483 . G <*> 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 X 484 . A <*> 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 X 485 . G <*> 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 X 486 . A <*> 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 X 487 . G <*> 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 X 488 . A <*> 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 X 489 . A <*> 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 X 490 . A <*> 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 X 491 . T <*> 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 X 492 . G <*> 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 X 493 . A <*> 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 X 494 . A <*> 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 X 495 . G <*> 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 X 496 . A <*> 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 X 497 . C <*> 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 X 498 . A <*> 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 X 499 . T <*> 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 X 500 . A <*> 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 X 501 . T <*> 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 X 502 . G <*> 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 X 503 . T <*> 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 X 504 . C <*> 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 X 505 . C <*> 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 X 506 . A <*> 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 X 507 . C <*> 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 X 508 . A <*> 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 X 509 . C <*> 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 X 510 . A <*> 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 X 511 . A <*> 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 X 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 X 513 . A <*> 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 X 514 . A T,<*> 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 X 515 . C <*> 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 X 516 . C <*> 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 X 517 . T <*> 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 X 518 . G <*> 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 X 519 . T <*> 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 X 520 . T <*> 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 X 521 . C <*> 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 X 522 . A <*> 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 X 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 X 524 . T <*> 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 X 525 . G <*> 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 X 526 . C <*> 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 X 527 . A <*> 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 X 528 . G <*> 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 X 529 . C <*> 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 X 530 . T <*> 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 X 531 . T <*> 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 X 532 . T <*> 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 X 533 . C <*> 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 X 534 . T <*> 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 X 535 . A <*> 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 X 536 . C <*> 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 X 537 . C <*> 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 X 538 . A <*> 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 X 539 . T <*> 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 X 540 . C <*> 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 X 541 . A <*> 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 X 542 . C <*> 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 X 543 . C <*> 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 X 544 . A <*> 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 X 545 . A <*> 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 X 546 . A <*> 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 X 547 . A <*> 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 X 548 . A <*> 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 X 549 . T G,<*> 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 X 550 . T <*> 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 X 551 . G <*> 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 X 552 . C <*> 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 X 553 . A <*> 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 X 554 . A <*> 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 X 555 . A <*> 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 X 556 . C <*> 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 X 557 . A <*> 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 X 558 . A <*> 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 X 559 . C A,<*> 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 X 560 . C <*> 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 X 561 . A <*> 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 X 562 . C <*> 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 X 563 . A <*> 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 X 564 . C <*> 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 X 565 . G <*> 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 X 566 . C <*> 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 X 567 . C <*> 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 X 568 . C <*> 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 X 569 . T <*> 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 X 570 . T <*> 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 X 571 . C <*> 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 X 572 . A <*> 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 X 573 . A <*> 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 X 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 X 575 . T <*> 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 X 576 . G <*> 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 X 577 . G <*> 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 X 578 . G <*> 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 X 579 . G <*> 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 X 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 X 581 . A <*> 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 X 582 . C <*> 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 X 583 . T <*> 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 X 584 . C <*> 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 X 585 . A <*> 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 X 586 . T <*> 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 X 587 . C <*> 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 X 588 . A <*> 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 X 589 . A <*> 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 X 590 . C <*> 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 X 591 . A <*> 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 X 592 . A <*> 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 X 593 . C <*> 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 X 594 . A <*> 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 X 595 . A <*> 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 X 596 . A <*> 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 X 597 . C <*> 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 X 598 . T <*> 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 X 599 . T <*> 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 X 600 . G <*> 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 X 601 . T <*> 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 X 602 . G <*> 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 X 603 . G <*> 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 X 604 . T <*> 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 X 605 . T <*> 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 X 606 . T <*> 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 X 607 . A <*> 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 X 608 . C <*> 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 X 609 . C <*> 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 X 610 . C <*> 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 X 611 . A <*> 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 X 612 . C <*> 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 X 613 . A <*> 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 X 614 . C <*> 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 X 615 . A <*> 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 X 616 . A <*> 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 X 617 . T <*> 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 X 618 . G <*> 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 X 619 . G <*> 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 X 620 . A <*> 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 X 621 . A <*> 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 X 622 . G <*> 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 X 623 . A T,<*> 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 X 624 . C <*> 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 X 625 . C <*> 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 X 626 . A <*> 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 X 627 . C <*> 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 X 628 . T <*> 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 X 629 . T <*> 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 X 630 . A <*> 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 X 631 . G <*> 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 X 632 . C <*> 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 X 633 . A <*> 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 X 634 . A <*> 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 X 635 . C <*> 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 X 636 . A <*> 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 X 637 . A <*> 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 X 638 . A <*> 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 X 639 . A <*> 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 X 640 . A <*> 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 X 641 . G <*> 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 X 642 . G <*> 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 X 643 . A <*> 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 X 644 . C A,<*> 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 X 645 . C <*> 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 X 646 . A T,<*> 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 X 647 . A <*> 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 X 648 . A <*> 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 X 649 . C <*> 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 X 650 . T <*> 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 X 651 . C <*> 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 X 652 . C <*> 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 X 653 . T <*> 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 X 654 . G <*> 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 X 655 . G <*> 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 X 656 . T <*> 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 X 657 . A <*> 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 X 658 . C <*> 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 X 659 . A <*> 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 X 660 . T <*> 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 X 661 . G <*> 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 X 662 . C <*> 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 X 663 . A <*> 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 X 664 . A <*> 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 X 665 . C <*> 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 X 666 . T <*> 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 X 667 . G <*> 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 X 668 . A <*> 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 X 669 . C <*> 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 X 670 . A <*> 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 X 671 . G <*> 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 X 672 . A <*> 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 X 673 . T <*> 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 X 674 . G <*> 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 X 675 . A <*> 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 X 676 . A <*> 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 X 677 . T <*> 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 X 678 . C <*> 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 X 679 . T <*> 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 X 680 . C <*> 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 X 681 . A <*> 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 X 682 . A <*> 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 X 683 . A <*> 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 X 684 . C <*> 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 X 685 . G <*> 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 X 686 . C <*> 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 X 687 . A <*> 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 X 688 . T <*> 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 X 689 . T A,<*> 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 X 690 . C <*> 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 X 691 . C <*> 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 X 692 . T <*> 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 X 693 . C <*> 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 X 694 . C <*> 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 X 695 . G <*> 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 X 696 . T <*> 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 X 697 . G <*> 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 X 698 . T <*> 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 X 699 . G <*> 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 X 700 . A <*> 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 X 701 . A <*> 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 X 702 . A <*> 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 X 703 . G <*> 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 X 704 . A T,<*> 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 X 705 . A <*> 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 X 706 . G <*> 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 X 707 . C <*> 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 X 708 . C <*> 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 X 709 . G <*> 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 X 710 . G <*> 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 X 711 . A <*> 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 X 712 . C <*> 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 X 713 . T <*> 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 X 714 . C <*> 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 X 715 . A <*> 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 X 716 . C <*> 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 X 717 . A <*> 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 X 718 . G <*> 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 X 719 . G <*> 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 X 720 . G <*> 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 X 721 . C <*> 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 X 722 . A <*> 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 X 723 . A <*> 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 X 724 . C <*> 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 X 725 . A <*> 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 X 726 . C <*> 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 X 727 . A C,<*> 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 X 728 . C <*> 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 X 729 . T <*> 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 X 730 . A <*> 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 X 731 . T <*> 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 X 732 . C <*> 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 X 733 . T <*> 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 X 734 . G <*> 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 X 735 . A <*> 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 X 736 . C <*> 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 X 737 . T <*> 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 X 738 . G <*> 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 X 739 . T <*> 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 X 740 . T <*> 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 X 741 . T <*> 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 X 742 . C <*> 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 X 743 . A <*> 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 X 744 . T <*> 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 X 745 . G <*> 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 X 746 . G <*> 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 X 747 . G <*> 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 X 748 . A <*> 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 X 749 . A <*> 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 X 750 . A <*> 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 X 751 . G <*> 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 X 752 . T <*> 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 X 753 . C <*> 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 X 754 . T <*> 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 X 755 . G <*> 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 X 756 . G <*> 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 X 757 . A <*> 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 X 758 . A <*> 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 X 759 . A <*> 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 X 760 . C <*> 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 X 761 . G <*> 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 X 762 . G <*> 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 X 763 . C A,<*> 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 X 764 . A <*> 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 X 765 . A <*> 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 X 766 . C <*> 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 X 767 . A <*> 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 X 768 . C <*> 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 X 769 . C <*> 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 X 770 . A <*> 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 X 771 . T <*> 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 X 772 . T <*> 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 X 773 . G <*> 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 X 774 . A <*> 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 X 775 . G <*> 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 X 776 . A <*> 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 X 777 . C <*> 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 X 778 . A <*> 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 X 779 . G <*> 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 X 780 . A <*> 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 X 781 . A <*> 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 X 782 . A <*> 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 X 783 . A <*> 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 X 784 . C <*> 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 X 785 . A <*> 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 X 786 . G <*> 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 X 787 . G <*> 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 X 788 . T <*> 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 X 789 . G <*> 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 X 790 . A <*> 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 X 791 . G <*> 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 X 792 . T <*> 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 X 793 . G <*> 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 X 794 . G <*> 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 X 795 . T <*> 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 X 796 . T <*> 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 X 797 . G <*> 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 X 798 . C <*> 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 X 799 . C <*> 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 X 800 . T <*> 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 X 801 . G <*> 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 X 802 . G <*> 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 X 803 . G <*> 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 X 804 . G <*> 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 X 805 . C <*> 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 X 806 . C <*> 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 X 807 . A <*> 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 X 808 . G <*> 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 X 809 . G <*> 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 X 810 . G C,<*> 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 X 811 . A <*> 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 X 812 . A <*> 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 X 813 . C <*> 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 X 814 . T <*> 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 X 815 . T <*> 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 X 816 . T <*> 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 X 817 . C <*> 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 X 818 . T <*> 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 X 819 . G <*> 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 X 820 . G <*> 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 X 821 . G <*> 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 X 822 . G <*> 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 X 823 . T <*> 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 X 824 . C <*> 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 X 825 . A <*> 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 X 826 . T <*> 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 X 827 . A <*> 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 X 828 . T C,<*> 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 X 829 . T <*> 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 X 830 . C <*> 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 X 831 . T <*> 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 X 832 . C <*> 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 X 833 . T <*> 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 X 834 . G A,<*> 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 X 835 . T <*> 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 X 836 . G <*> 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 X 837 . T <*> 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 X 838 . T <*> 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 X 839 . G <*> 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 X 840 . A <*> 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 X 841 . T <*> 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 X 842 . T <*> 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 X 843 . C <*> 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 X 844 . T <*> 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 X 845 . G <*> 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 X 846 . G <*> 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 X 847 . T <*> 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 X 848 . G <*> 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 X 849 . G <*> 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 X 850 . T <*> 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 X 851 . G <*> 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 X 852 . G <*> 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 X 853 . A <*> 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 X 854 . A <*> 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 X 855 . A <*> 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 X 856 . C <*> 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 X 857 . A <*> 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 X 858 . A <*> 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 X 859 . G <*> 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 X 860 . A <*> 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 X 861 . C <*> 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 X 862 . T <*> 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 X 863 . G <*> 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 X 864 . T <*> 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 X 865 . C <*> 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 X 866 . C <*> 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 X 867 . C <*> 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 X 868 . A <*> 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 X 869 . G <*> 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 X 870 . C <*> 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 X 871 . C <*> 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 X 872 . T <*> 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 X 873 . G <*> 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 X 874 . G <*> 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 X 875 . G <*> 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 X 876 . T <*> 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 X 877 . G <*> 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 X 878 . A <*> 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 X 879 . T <*> 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 X 880 . A <*> 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 X 881 . C <*> 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 X 882 . A <*> 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 X 883 . G <*> 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 X 884 . C <*> 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 X 885 . G <*> 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 X 886 . A <*> 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 X 887 . G <*> 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 X 888 . A <*> 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 X 889 . C <*> 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 X 890 . C <*> 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 X 891 . C <*> 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 X 892 . C <*> 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 X 893 . A <*> 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 X 894 . T <*> 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 X 895 . C <*> 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 X 896 . T <*> 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 X 897 . C <*> 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 X 898 . T <*> 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 X 899 . A <*> 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 X 900 . C <*> 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 X 901 . C <*> 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 X 902 . A <*> 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 X 903 . A <*> 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 X 904 . A <*> 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 X 905 . A <*> 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 X 906 . A <*> 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 X 907 . A <*> 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 X 908 . T <*> 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 X 909 . T <*> 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 X 910 . A <*> 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 X 911 . A <*> 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 X 912 . A <*> 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 X 913 . A <*> 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 X 914 . A <*> 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 X 915 . T <*> 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 X 916 . T <*> 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 X 917 . A <*> 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 X 918 . G <*> 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 X 919 . C <*> 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 X 920 . T <*> 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 X 921 . G <*> 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 X 922 . G <*> 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 X 923 . G <*> 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 X 924 . C <*> 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 X 925 . A <*> 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 X 926 . T <*> 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 X 927 . G <*> 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 X 928 . G <*> 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 X 929 . T <*> 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 X 930 . G <*> 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 X 931 . G <*> 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 X 932 . T <*> 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 X 933 . G <*> 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 X 934 . C <*> 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 X 935 . A <*> 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 X 936 . T <*> 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 X 937 . G <*> 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 X 938 . C <*> 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 X 939 . C <*> 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 X 940 . T <*> 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 X 941 . G <*> 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 X 942 . T <*> 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 X 943 . A <*> 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 X 944 . G <*> 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 X 945 . T <*> 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 X 946 . C <*> 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 X 947 . C <*> 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 X 948 . C <*> 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 X 949 . A <*> 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 X 950 . G <*> 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 X 951 . C <*> 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 X 952 . T <*> 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 X 953 . A <*> 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 X 954 . T <*> 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 X 955 . T <*> 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 X 956 . C <*> 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 X 957 . A <*> 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 X 958 . C <*> 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 X 959 . A <*> 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 X 960 . G <*> 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 X 961 . T <*> 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 X 962 . G <*> 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 X 963 . C <*> 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 X 964 . T <*> 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 X 965 . G <*> 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 X 966 . A <*> 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 X 967 . G <*> 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 X 968 . G <*> 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 X 969 . T <*> 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 X 970 . G <*> 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 X 971 . G <*> 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 X 972 . G <*> 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 X 973 . A <*> 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 X 974 . A <*> 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 X 975 . G <*> 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 X 976 . A <*> 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 X 977 . T <*> 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 X 978 . G <*> 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 X 979 . C <*> 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 X 980 . T <*> 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 X 981 . T <*> 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 X 982 . G <*> 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 X 983 . A <*> 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 X 984 . G <*> 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 X 985 . C <*> 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 X 986 . C A,<*> 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 X 987 . C <*> 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 X 988 . A <*> 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 X 989 . G <*> 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 X 990 . G <*> 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 X 991 . A <*> 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 X 992 . G <*> 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 X 993 . T <*> 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 X 994 . T <*> 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 X 995 . C <*> 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 X 996 . A <*> 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 X 997 . A <*> 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 X 998 . G <*> 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 X 999 . G <*> 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 X 1000 . C <*> 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 X 1001 . T <*> 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 X 1002 . G <*> 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 X 1003 . C T,<*> 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 X 1004 . A <*> 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 X 1005 . A <*> 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 X 1006 . T <*> 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 X 1007 . G <*> 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 X 1008 . A <*> 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 X 1009 . G <*> 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 X 1010 . C <*> 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 X 1011 . T <*> 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 X 1012 . A <*> 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 X 1013 . T <*> 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 X 1014 . G <*> 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 X 1015 . A <*> 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 X 1016 . T <*> 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 X 1017 . T <*> 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 X 1018 . G <*> 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 X 1019 . C <*> 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 X 1020 . G <*> 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 X 1021 . C <*> 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 X 1022 . C <*> 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 X 1023 . A <*> 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 X 1024 . C <*> 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 X 1025 . T <*> 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 X 1026 . G <*> 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 X 1027 . C <*> 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 X 1028 . A <*> 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 X 1029 . C <*> 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 X 1030 . T <*> 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 X 1031 . T <*> 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 X 1032 . T <*> 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 X 1033 . G <*> 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 X 1034 . G <*> 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 X 1035 . C <*> 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 X 1036 . C <*> 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 X 1037 . T <*> 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 X 1038 . G <*> 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 X 1039 . G <*> 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 X 1040 . A <*> 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 X 1041 . C <*> 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 X 1042 . A <*> 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 X 1043 . A <*> 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 X 1044 . C <*> 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 X 1045 . A <*> 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 X 1046 . G <*> 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 X 1047 . A <*> 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 X 1048 . G <*> 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 X 1049 . C <*> 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 X 1050 . A <*> 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 X 1051 . A <*> 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 X 1052 . A <*> 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 X 1053 . A <*> 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 X 1054 . C <*> 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 X 1055 . C <*> 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 X 1056 . C <*> 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 X 1057 . T <*> 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 X 1058 . G <*> 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 X 1059 . T <*> 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 X 1060 . C <*> 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 X 1061 . T <*> 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 X 1062 . C A,<*> 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 X 1063 . T <*> 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 X 1064 . A <*> 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 X 1065 . A <*> 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 X 1066 . A <*> 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 X 1067 . A <*> 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 X 1068 . A <*> 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 X 1069 . A <*> 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 X 1070 . A <*> 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 X 1071 . G <*> 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 X 1072 . A <*> 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 X 1073 . A <*> 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 X 1074 . A <*> 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 X 1075 . A <*> 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 X 1076 . G <*> 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 X 1077 . A <*> 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 X 1078 . A <*> 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 X 1079 . A <*> 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 X 1080 . A <*> 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 X 1081 . G <*> 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 X 1082 . A <*> 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 X 1083 . A <*> 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 X 1084 . A <*> 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 X 1085 . A <*> 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 X 1086 . A <*> 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 X 1087 . C <*> 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 X 1088 . T <*> 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 X 1089 . C <*> 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 X 1090 . A <*> 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 X 1091 . C <*> 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 X 1092 . T <*> 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 X 1093 . G <*> 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 X 1094 . G <*> 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 X 1095 . A <*> 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 X 1096 . T <*> 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 X 1097 . A <*> 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 X 1098 . T <*> 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 X 1099 . G <*> 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 X 1100 . A <*> 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 X 1101 . A <*> 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 X 1102 . T <*> 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 X 1103 . G <*> 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 X 1104 . A <*> 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 X 1105 . T <*> 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 X 1106 . A <*> 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 X 1107 . C <*> 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 X 1108 . A <*> 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 X 1109 . G <*> 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 X 1110 . G <*> 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 X 1111 . T <*> 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 X 1112 . T <*> 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 X 1113 . G <*> 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 X 1114 . A <*> 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 X 1115 . G <*> 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 X 1116 . G <*> 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 X 1117 . A <*> 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 X 1118 . T <*> 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 X 1119 . C <*> 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 X 1120 . C <*> 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 X 1121 . A <*> 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 X 1122 . T <*> 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 X 1123 . T <*> 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 X 1124 . A <*> 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 X 1125 . T <*> 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 X 1126 . C <*> 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 X 1127 . T <*> 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 X 1128 . G <*> 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 X 1129 . A G,<*> 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 X 1130 . A <*> 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 X 1131 . A <*> 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 X 1132 . T <*> 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 X 1133 . G <*> 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 X 1134 . C <*> 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 X 1135 . T <*> 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 X 1136 . T <*> 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 X 1137 . G <*> 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 X 1138 . G <*> 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 X 1139 . A <*> 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 X 1140 . C <*> 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 X 1141 . C <*> 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 X 1142 . A <*> 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 X 1143 . G <*> 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 X 1144 . A <*> 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 X 1145 . T <*> 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 X 1146 . G <*> 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 X 1147 . T <*> 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 X 1148 . T <*> 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 X 1149 . T <*> 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 X 1150 . T <*> 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 X 1151 . G <*> 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 X 1152 . A <*> 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 X 1153 . A <*> 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 X 1154 . T <*> 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 X 1155 . T <*> 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 X 1156 . T <*> 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 X 1157 . T <*> 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 X 1158 . G <*> 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 X 1159 . G <*> 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 X 1160 . A <*> 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 X 1161 . T <*> 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 X 1162 . T <*> 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 X 1163 . T <*> 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 X 1164 . T <*> 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 X 1165 . T <*> 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 X 1166 . T <*> 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 X 1167 . C <*> 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 X 1168 . A <*> 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 X 1169 . T <*> 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 X 1170 . A <*> 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 X 1171 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 X 1172 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 X 1173 . T <*> 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 X 1174 . T <*> 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 X 1175 . G <*> 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 X 1176 . T <*> 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 X 1177 . A <*> 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 X 1178 . A <*> 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 X 1179 . T <*> 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 X 1180 . C <*> 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 X 1181 . T <*> 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 X 1182 . T <*> 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 X 1183 . T <*> 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 X 1184 . G <*> 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 X 1185 . C <*> 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 X 1186 . A <*> 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 X 1187 . G <*> 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 X 1188 . T <*> 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 X 1189 . A <*> 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 X 1190 . T <*> 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 X 1191 . A <*> 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 X 1192 . T <*> 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 X 1193 . T <*> 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 X 1194 . T <*> 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 X 1195 . A <*> 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 X 1196 . C <*> 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 X 1197 . C <*> 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 X 1198 . A <*> 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 X 1199 . G <*> 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 X 1200 . T <*> 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 X 1201 . T <*> 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 X 1202 . C <*> 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 X 1203 . A <*> 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 X 1204 . G <*> 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 X 1205 . C <*> 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 X 1206 . A <*> 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 X 1207 . T <*> 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 X 1208 . C <*> 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 X 1209 . C T,<*> 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 X 1210 . C <*> 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 X 1211 . T <*> 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 X 1212 . A <*> 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 X 1213 . A <*> 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 X 1214 . C <*> 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 X 1215 . T <*> 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 X 1216 . C <*> 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 X 1217 . A <*> 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 X 1218 . A <*> 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 X 1219 . A <*> 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 X 1220 . A <*> 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 X 1221 . A <*> 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 X 1222 . T <*> 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 X 1223 . T <*> 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 X 1224 . C <*> 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 X 1225 . A <*> 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 X 1226 . A <*> 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 X 1227 . A <*> 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 X 1228 . A <*> 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 X 1229 . A <*> 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 X 1230 . T <*> 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 X 1231 . C <*> 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 X 1232 . T <*> 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 X 1233 . G <*> 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 X 1234 . A <*> 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 X 1235 . A <*> 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 X 1236 . A <*> 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 X 1237 . T <*> 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 X 1238 . C <*> 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 X 1239 . C <*> 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 X 1240 . C <*> 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 X 1241 . A <*> 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 X 1242 . A <*> 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 X 1243 . A <*> 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 X 1244 . C <*> 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 X 1245 . G <*> 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 X 1246 . C <*> 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 X 1247 . G <*> 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 X 1248 . C <*> 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 X 1249 . C <*> 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 X 1250 . A <*> 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 X 1251 . A <*> 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 X 1252 . T <*> 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 X 1253 . A <*> 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 X 1254 . A <*> 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 X 1255 . G <*> 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 X 1256 . C <*> 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 X 1257 . A <*> 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 X 1258 . T <*> 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 X 1259 . T <*> 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 X 1260 . C <*> 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 X 1261 . C <*> 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 X 1262 . C <*> 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 X 1263 . T <*> 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 X 1264 . T <*> 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 X 1265 . T <*> 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 X 1266 . G <*> 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 X 1267 . A <*> 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 X 1268 . G <*> 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 X 1269 . C <*> 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 X 1270 . G <*> 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 X 1271 . T <*> 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 X 1272 . C <*> 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 X 1273 . A <*> 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 X 1274 . T <*> 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 X 1275 . G <*> 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 X 1276 . T <*> 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 X 1277 . C <*> 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 X 1278 . G <*> 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 X 1279 . G <*> 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 X 1280 . T <*> 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 X 1281 . G <*> 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 X 1282 . C <*> 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 X 1283 . T <*> 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 X 1284 . T <*> 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 X 1285 . G <*> 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 X 1286 . G <*> 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 X 1287 . A <*> 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 X 1288 . A <*> 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 X 1289 . T <*> 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 X 1290 . G <*> 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 X 1291 . T <*> 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 X 1292 . T <*> 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 X 1293 . T <*> 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 X 1294 . G <*> 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 X 1295 . G <*> 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 X 1296 . G <*> 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 X 1297 . G <*> 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 X 1298 . T <*> 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 X 1299 . T <*> 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 X 1300 . T <*> 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 X 1301 . T G,<*> 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 X 1302 . G <*> 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 X 1303 . G <*> 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 X 1304 . A <*> 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 X 1305 . T <*> 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 X 1306 . T <*> 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 X 1307 . T <*> 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 X 1308 . A <*> 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 X 1309 . C <*> 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 X 1310 . A <*> 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 X 1311 . G <*> 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 X 1312 . C <*> 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 X 1313 . T <*> 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 X 1314 . T <*> 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 X 1315 . T <*> 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 X 1316 . G <*> 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 X 1317 . G <*> 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 X 1318 . G <*> 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 X 1319 . A <*> 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 X 1320 . C <*> 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 X 1321 . G <*> 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 X 1322 . C <*> 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 X 1323 . T <*> 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 X 1324 . C <*> 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 X 1325 . A <*> 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 X 1326 . A <*> 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 X 1327 . C <*> 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 X 1328 . C <*> 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 X 1329 . T <*> 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 X 1330 . G <*> 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 X 1331 . T <*> 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 X 1332 . A <*> 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 X 1333 . C <*> 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 X 1334 . C <*> 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 X 1335 . T <*> 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 X 1336 . C <*> 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 X 1337 . A <*> 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 X 1338 . A <*> 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 X 1339 . T <*> 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 X 1340 . A <*> 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 X 1341 . A <*> 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 X 1342 . A <*> 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 X 1343 . C <*> 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 X 1344 . C <*> 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 X 1345 . T <*> 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 X 1346 . G <*> 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 X 1347 . A <*> 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 X 1348 . T <*> 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 X 1349 . T <*> 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 X 1350 . T <*> 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 X 1351 . T <*> 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 X 1352 . A <*> 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 X 1353 . A <*> 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 X 1354 . A <*> 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 X 1355 . A <*> 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 X 1356 . A <*> 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 X 1357 . A <*> 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 X 1358 . G <*> 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 X 1359 . T <*> 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 X 1360 . T <*> 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 X 1361 . T <*> 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 X 1362 . G <*> 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 X 1363 . G <*> 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 X 1364 . G <*> 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 X 1365 . G <*> 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 X 1366 . G <*> 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 X 1367 . G C,<*> 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 X 1368 . A <*> 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 X 1369 . T <*> 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 X 1370 . T <*> 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 X 1371 . C <*> 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 X 1372 . C <*> 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 X 1373 . C <*> 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 X 1374 . C <*> 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 X 1375 . T <*> 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 X 1376 . A <*> 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 X 1377 . A <*> 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 X 1378 . G <*> 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 X 1379 . C <*> 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 X 1380 . C <*> 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 X 1381 . C <*> 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 X 1382 . G <*> 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 X 1383 . C <*> 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 X 1384 . C <*> 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 X 1385 . A <*> 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 X 1386 . C <*> 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 X 1387 . C <*> 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 X 1388 . C <*> 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 X 1389 . G <*> 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 X 1390 . G <*> 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 X 1391 . A <*> 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 X 1392 . G <*> 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 X 1393 . A <*> 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 X 1394 . C <*> 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 X 1395 . A <*> 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 X 1396 . G <*> 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 X 1397 . C <*> 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 X 1398 . G <*> 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 X 1399 . G <*> 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 X 1400 . A <*> 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 X 1401 . T <*> 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 X 1402 . T <*> 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 X 1403 . T <*> 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 X 1404 . C <*> 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 X 1405 . C <*> 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 X 1406 . T <*> 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 X 1407 . T <*> 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 X 1408 . A <*> 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 X 1409 . G <*> 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 X 1410 . T <*> 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 X 1411 . T <*> 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 X 1412 . A T,<*> 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 X 1413 . C <*> 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 X 1414 . T <*> 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 X 1415 . T <*> 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 X 1416 . A <*> 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 X 1417 . C <*> 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 X 1418 . T <*> 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 X 1419 . A <*> 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 X 1420 . T <*> 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 X 1421 . G <*> 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 X 1422 . C <*> 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 X 1423 . T <*> 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 X 1424 . C <*> 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 X 1425 . C <*> 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 X 1426 . T <*> 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 X 1427 . T <*> 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 X 1428 . G <*> 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 X 1429 . G <*> 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 X 1430 . C <*> 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 X 1431 . C <*> 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 X 1432 . A <*> 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 X 1433 . T <*> 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 X 1434 . T <*> 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 X 1435 . T <*> 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 X 1436 . C <*> 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 X 1437 . T <*> 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 X 1438 . C <*> 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 X 1439 . T <*> 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 X 1440 . A <*> 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 X 1441 . G <*> 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 X 1442 . G <*> 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 X 1443 . T <*> 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 X 1444 . A <*> 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 X 1445 . T <*> 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 X 1446 . T <*> 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 X 1447 . G <*> 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 X 1448 . G <*> 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 X 1449 . T <*> 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 X 1450 . A <*> 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 X 1451 . T <*> 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 X 1452 . A <*> 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 X 1453 . T <*> 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 X 1454 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 X 1455 . G <*> 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 X 1456 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 X 1457 . G <*> 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 X 1458 . T <*> 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 X 1459 . C A,<*> 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 X 1460 . T <*> 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 X 1461 . G <*> 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 X 1462 . C <*> 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 X 1463 . T <*> 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 X 1464 . G <*> 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 X 1465 . T <*> 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 X 1466 . G <*> 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 X 1467 . A <*> 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 X 1468 . A <*> 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 X 1469 . C T,<*> 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 X 1470 . T <*> 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 X 1471 . G <*> 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 X 1472 . T <*> 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 X 1473 . C <*> 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 X 1474 . C <*> 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 X 1475 . T <*> 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 X 1476 . T G,<*> 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 X 1477 . G <*> 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 X 1478 . G <*> 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 X 1479 . C <*> 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 X 1480 . C <*> 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 X 1481 . T <*> 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 X 1482 . G <*> 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 X 1483 . T <*> 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 X 1484 . T <*> 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 X 1485 . T <*> 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 X 1486 . G <*> 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 X 1487 . G <*> 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 X 1488 . T <*> 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 X 1489 . G <*> 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 X 1490 . A <*> 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 X 1491 . C <*> 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 X 1492 . G <*> 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 X 1493 . G <*> 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 X 1494 . G <*> 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 X 1495 . T <*> 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 X 1496 . G <*> 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 X 1497 . A <*> 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 X 1498 . G <*> 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 X 1499 . G <*> 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 X 1500 . A <*> 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 X 1501 . G <*> 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 X 1502 . C <*> 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 X 1503 . A <*> 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 X 1504 . G <*> 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 X 1505 . G <*> 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 X 1506 . G <*> 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 X 1507 . A <*> 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 X 1508 . C <*> 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 X 1509 . A <*> 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 X 1510 . G <*> 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 X 1511 . A <*> 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 X 1512 . A <*> 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 X 1513 . G <*> 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 X 1514 . G <*> 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 X 1515 . G <*> 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 X 1516 . T <*> 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 X 1517 . C <*> 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 X 1518 . C <*> 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 X 1519 . T <*> 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 X 1520 . G <*> 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 X 1521 . C <*> 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 X 1522 . G <*> 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 X 1523 . T <*> 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 X 1524 . G <*> 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 X 1525 . C <*> 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 X 1526 . C <*> 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 X 1527 . C <*> 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 X 1528 . T <*> 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 X 1529 . G <*> 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 X 1530 . C <*> 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 X 1531 . C <*> 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 X 1532 . T <*> 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 X 1533 . T <*> 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 X 1534 . C <*> 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 X 1535 . A <*> 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 X 1536 . C <*> 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 X 1537 . A <*> 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 X 1538 . A <*> 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 X 1539 . G <*> 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 X 1540 . C <*> 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 X 1541 . C <*> 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 X 1542 . C <*> 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 X 1543 . C <*> 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 X 1544 . T <*> 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 X 1545 . G <*> 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 X 1546 . G <*> 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 X 1547 . A <*> 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 X 1548 . A <*> 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 X 1549 . G <*> 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 X 1550 . G <*> 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 X 1551 . A <*> 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 X 1552 . A <*> 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 X 1553 . A <*> 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 X 1554 . G <*> 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 X 1555 . T <*> 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 X 1556 . T <*> 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 X 1557 . G <*> 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 X 1558 . T <*> 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 X 1559 . T <*> 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 X 1560 . T <*> 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 X 1561 . T <*> 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 X 1562 . G <*> 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 X 1563 . G <*> 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 X 1564 . G <*> 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 X 1565 . A <*> 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 X 1566 . T <*> 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 X 1567 . C <*> 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 X 1568 . T <*> 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 X 1569 . C <*> 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 X 1570 . T <*> 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 X 1571 . G <*> 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 X 1572 . C <*> 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 X 1573 . A <*> 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 X 1574 . C <*> 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 X 1575 . C <*> 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 X 1576 . C <*> 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 X 1577 . T <*> 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 X 1578 . C <*> 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 X 1579 . A <*> 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 X 1580 . G <*> 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 X 1581 . C <*> 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 X 1582 . C <*> 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 X 1583 . T <*> 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 X 1584 . G <*> 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 X 1585 . G <*> 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 X 1586 . A <*> 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 X 1587 . C <*> 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 X 1588 . A <*> 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 X 1589 . A <*> 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 X 1590 . C <*> 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 X 1591 . T <*> 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 X 1592 . T <*> 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 X 1593 . G <*> 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 X 1594 . T <*> 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 X 1595 . G <*> 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 X 1596 . C <*> 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 X 1597 . C <*> 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 X 1598 . C <*> 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 X 1599 . A <*> 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 X 1600 . T <*> 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 X 1601 . C <*> 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 X 1602 . T <*> 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 X 1603 . G <*> 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 X 1604 . G <*> 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 X 1605 . T <*> 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 X 1606 . G <*> 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 X 1607 . A <*> 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 X 1608 . C <*> 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 X 1609 . C <*> 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 X 1610 . C <*> 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 X 1611 . C <*> 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 X 1612 . T <*> 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 X 1613 . C <*> 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 X 1614 . A <*> 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 X 1615 . C <*> 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 X 1616 . T <*> 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 X 1617 . C <*> 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 X 1618 . A <*> 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 X 1619 . G <*> 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 X 1620 . C <*> 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 X 1621 . C <*> 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 X 1622 . A <*> 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 X 1623 . C <*> 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 X 1624 . C <*> 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 X 1625 . A <*> 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 X 1626 . G <*> 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 X 1627 . A <*> 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 X 1628 . C <*> 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 X 1629 . T <*> 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 X 1630 . T <*> 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 X 1631 . C <*> 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 X 1632 . C <*> 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 X 1633 . A <*> 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 X 1634 . C <*> 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 X 1635 . G <*> 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 X 1636 . A <*> 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 X 1637 . C <*> 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 X 1638 . A <*> 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 X 1639 . G <*> 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 X 1640 . G <*> 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 X 1641 . C <*> 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 X 1642 . T <*> 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 X 1643 . C <*> 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 X 1644 . C <*> 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 X 1645 . A <*> 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 X 1646 . G <*> 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 X 1647 . C <*> 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 X 1648 . C <*> 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 X 1649 . T <*> 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 X 1650 . C <*> 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 X 1651 . G <*> 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 X 1652 . G <*> 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 X 1653 . C <*> 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 X 1654 . A T,<*> 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 X 1655 . C <*> 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 X 1656 . C <*> 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 X 1657 . T A,<*> 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 X 1658 . T <*> 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 X 1659 . C <*> 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 X 1660 . A <*> 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 X 1661 . G <*> 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 X 1662 . C <*> 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 X 1663 . C <*> 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 X 1664 . A C,<*> 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 X 1665 . T C,<*> 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 X 1666 . G <*> 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 X 1667 . G <*> 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 X 1668 . A <*> 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 X 1669 . C <*> 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 X 1670 . A <*> 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 X 1671 . G <*> 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 X 1672 . T <*> 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 X 1673 . T <*> 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 X 1674 . C <*> 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 X 1675 . C <*> 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 X 1676 . G <*> 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 X 1677 . C <*> 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 X 1678 . C <*> 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 X 1679 . A <*> 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 X 1680 . G <*> 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 X 1681 . C <*> 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 X 1682 . G <*> 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 X 1683 . T <*> 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 X 1684 . T <*> 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 X 1685 . G <*> 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 X 1686 . C <*> 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 X 1687 . C <*> 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 X 1688 . C <*> 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 X 1689 . T A,<*> 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 X 1690 . C <*> 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 X 1691 . T <*> 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 X 1692 . G <*> 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 X 1693 . T <*> 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 X 1694 . T <*> 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 X 1695 . C <*> 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 X 1696 . T <*> 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 X 1697 . G <*> 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 X 1698 . C A,<*> 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 X 1699 . T <*> 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 X 1700 . G <*> 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 X 1701 . T <*> 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 X 1702 . T <*> 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 X 1703 . T <*> 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 X 1704 . T <*> 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 X 1705 . C <*> 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 X 1706 . T <*> 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 X 1707 . C <*> 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 X 1708 . T <*> 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 X 1709 . A <*> 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 X 1710 . C <*> 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 X 1711 . C <*> 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 X 1712 . A <*> 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 X 1713 . G <*> 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 X 1714 . A <*> 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 X 1715 . A <*> 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 X 1716 . G <*> 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 X 1717 . T <*> 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 X 1718 . G <*> 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 X 1719 . C <*> 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 X 1720 . C <*> 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 X 1721 . C <*> 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 X 1722 . T <*> 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 X 1723 . T <*> 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 X 1724 . C <*> 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 X 1725 . C G,<*> 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 X 1726 . C <*> 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 X 1727 . T <*> 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 X 1728 . C <*> 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 X 1729 . C <*> 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 X 1730 . T <*> 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 X 1731 . C <*> 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 X 1732 . A <*> 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 X 1733 . C <*> 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 X 1734 . C <*> 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 X 1735 . T <*> 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 X 1736 . G <*> 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 X 1737 . A <*> 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 X 1738 . C <*> 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 X 1739 . C <*> 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 X 1740 . A <*> 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 X 1741 . C <*> 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 X 1742 . T <*> 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 X 1743 . C <*> 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 X 1744 . T <*> 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 X 1745 . G <*> 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 X 1746 . G <*> 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 X 1747 . G <*> 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 X 1748 . G <*> 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 X 1749 . A <*> 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 X 1750 . A <*> 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 X 1751 . A <*> 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 X 1752 . T <*> 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 X 1753 . C <*> 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 X 1754 . C <*> 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 X 1755 . C <*> 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 X 1756 . T <*> 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 X 1757 . C <*> 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 X 1758 . A <*> 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 X 1759 . G <*> 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 X 1760 . C <*> 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 X 1761 . A <*> 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 X 1762 . C <*> 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 X 1763 . C <*> 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 X 1764 . C <*> 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 X 1765 . T <*> 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 X 1766 . C <*> 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 X 1767 . C <*> 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 X 1768 . C <*> 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 X 1769 . T <*> 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 X 1770 . G <*> 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 X 1771 . A <*> 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 X 1772 . G <*> 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 X 1773 . C <*> 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 X 1774 . A <*> 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 X 1775 . T <*> 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 X 1776 . A <*> 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 X 1777 . C <*> 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 X 1778 . C <*> 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 X 1779 . C <*> 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 X 1780 . T <*> 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 X 1781 . A <*> 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 X 1782 . C <*> 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 X 1783 . T <*> 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 X 1784 . C <*> 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 X 1785 . T <*> 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 X 1786 . G <*> 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 X 1787 . G <*> 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 X 1788 . C <*> 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 X 1789 . A <*> 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 X 1790 . C <*> 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 X 1791 . A <*> 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 X 1792 . A <*> 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 X 1793 . G <*> 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 X 1794 . C <*> 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 X 1795 . C <*> 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 X 1796 . C <*> 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 X 1797 . A <*> 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 X 1798 . C <*> 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 X 1799 . C <*> 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 X 1800 . C <*> 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 X 1801 . T <*> 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 X 1802 . G <*> 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 X 1803 . C <*> 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 X 1804 . A <*> 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 X 1805 . A <*> 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 X 1806 . A <*> 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 X 1807 . G <*> 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 X 1808 . C <*> 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 X 1809 . C <*> 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 X 1810 . C <*> 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 X 1811 . C <*> 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 X 1812 . T <*> 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 X 1813 . G <*> 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 X 1814 . A <*> 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 X 1815 . G <*> 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 X 1816 . G <*> 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 X 1817 . C <*> 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 X 1818 . C <*> 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 X 1819 . C <*> 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 X 1820 . G <*> 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 X 1821 . C <*> 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 X 1822 . C <*> 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 X 1823 . C <*> 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 X 1824 . T <*> 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 X 1825 . G <*> 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 X 1826 . T <*> 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 X 1827 . G <*> 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 X 1828 . G <*> 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 X 1829 . C <*> 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 X 1830 . G <*> 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 X 1831 . T <*> 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 X 1832 . C <*> 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 X 1833 . T <*> 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 X 1834 . C <*> 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 X 1835 . T <*> 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 X 1836 . C <*> 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 X 1837 . C <*> 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 X 1838 . C <*> 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 X 1839 . T <*> 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 X 1840 . C <*> 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 X 1841 . C <*> 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 X 1842 . C <*> 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 X 1843 . T <*> 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 X 1844 . T <*> 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 X 1845 . G <*> 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 X 1846 . C <*> 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 X 1847 . T <*> 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 X 1848 . G <*> 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 X 1849 . T <*> 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 X 1850 . C <*> 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 X 1851 . A <*> 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 X 1852 . G <*> 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 X 1853 . G <*> 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 X 1854 . A <*> 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 X 1855 . C <*> 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 X 1856 . A <*> 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 X 1857 . G <*> 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 X 1858 . T <*> 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 X 1859 . G <*> 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 X 1860 . G <*> 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 X 1861 . T <*> 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 X 1862 . C <*> 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 X 1863 . C <*> 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 X 1864 . T <*> 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 X 1865 . G <*> 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 X 1866 . G <*> 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 X 1867 . C <*> 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 X 1868 . C <*> 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 X 1869 . A T,<*> 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 X 1870 . C <*> 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 X 1871 . C <*> 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 X 1872 . G <*> 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 X 1873 . G <*> 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 X 1874 . G <*> 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 X 1875 . G <*> 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 X 1876 . C <*> 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 X 1877 . T <*> 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 X 1878 . C <*> 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 X 1879 . A <*> 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 X 1880 . C <*> 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 X 1881 . G <*> 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 X 1882 . G <*> 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 X 1883 . A <*> 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 X 1884 . G <*> 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 X 1885 . C <*> 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 X 1886 . C <*> 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 X 1887 . G <*> 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 X 1888 . C <*> 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 X 1889 . C <*> 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 X 1890 . C <*> 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 X 1891 . T <*> 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 X 1892 . G <*> 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 X 1893 . T <*> 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 X 1894 . G <*> 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 X 1895 . C <*> 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 X 1896 . C <*> 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 X 1897 . G <*> 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 X 1898 . T <*> 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 X 1899 . G <*> 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 X 1900 . T <*> 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 X 1901 . A <*> 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 X 1902 . C <*> 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 X 1903 . C <*> 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 X 1904 . T <*> 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 X 1905 . C <*> 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 X 1906 . T <*> 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 X 1907 . G <*> 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 X 1908 . A <*> 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 X 1909 . G <*> 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 X 1910 . C <*> 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 X 1911 . C <*> 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 X 1912 . C <*> 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 X 1913 . T <*> 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 X 1914 . C <*> 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 X 1915 . T C,<*> 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 X 1916 . G T,<*> 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 X 1917 . C <*> 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 X 1918 . A <*> 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 X 1919 . C <*> 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 X 1920 . A T,<*> 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 X 1921 . G <*> 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 X 1922 . T <*> 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 X 1923 . G <*> 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 X 1924 . C <*> 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 X 1925 . C <*> 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 X 1926 . T <*> 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 X 1927 . T <*> 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 X 1928 . C <*> 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 X 1929 . T <*> 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 X 1930 . G <*> 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 X 1931 . C <*> 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 X 1932 . T <*> 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 X 1933 . T <*> 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 X 1934 . G <*> 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 X 1935 . C <*> 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 X 1936 . C <*> 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 X 1937 . T <*> 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 X 1938 . G <*> 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 X 1939 . T <*> 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 X 1940 . G <*> 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 X 1941 . G <*> 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 X 1942 . C <*> 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 X 1943 . T <*> 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 X 1944 . T <*> 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 X 1945 . T <*> 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 X 1946 . G <*> 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 X 1947 . A <*> 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 X 1948 . G C,<*> 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 X 1949 . A <*> 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 X 1950 . A <*> 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 X 1951 . G <*> 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 X 1952 . A <*> 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 X 1953 . A <*> 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 X 1954 . A C,<*> 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 X 1955 . C <*> 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 X 1956 . C <*> 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 X 1957 . C <*> 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 X 1958 . C <*> 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 X 1959 . T <*> 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 X 1960 . T <*> 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 X 1961 . C <*> 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 X 1962 . T <*> 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 X 1963 . G <*> 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 X 1964 . G <*> 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 X 1965 . T <*> 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 X 1966 . T <*> 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 X 1967 . A <*> 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 X 1968 . T <*> 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 X 1969 . A <*> 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 X 1970 . C <*> 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 X 1971 . A <*> 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 X 1972 . T <*> 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 X 1973 . A <*> 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 X 1974 . A <*> 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 X 1975 . G <*> 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 X 1976 . A <*> 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 X 1977 . C <*> 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 X 1978 . A <*> 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 X 1979 . G <*> 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 X 1980 . C <*> 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 X 1981 . C <*> 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 X 1982 . A <*> 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 X 1983 . G <*> 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 X 1984 . A <*> 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 X 1985 . G <*> 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 X 1986 . A <*> 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 X 1987 . A <*> 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 X 1988 . G <*> 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 X 1989 . G <*> 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 X 1990 . G T,<*> 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 X 1991 . A <*> 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 X 1992 . G <*> 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 X 1993 . T <*> 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 X 1994 . T <*> 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 X 1995 . G <*> 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 X 1996 . C <*> 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 X 1997 . C <*> 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 X 1998 . C <*> 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 X 1999 . A <*> 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 X 2000 . G <*> 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 X 2001 . G <*> 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 X 2002 . G <*> 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 X 2003 . T <*> 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 X 2004 . G <*> 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 X 2005 . G <*> 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 X 2006 . C <*> 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 X 2007 . A <*> 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 X 2008 . C <*> 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 X 2009 . A <*> 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 X 2010 . G <*> 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 X 2011 . C <*> 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 X 2012 . A <*> 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 X 2013 . C <*> 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 X 2014 . G <*> 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 X 2015 . T <*> 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 X 2016 . T <*> 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 X 2017 . G <*> 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 X 2018 . C <*> 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 X 2019 . T <*> 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 X 2020 . G <*> 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 X 2021 . C <*> 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 X 2022 . C <*> 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 X 2023 . A <*> 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 X 2024 . G <*> 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 X 2025 . T <*> 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 X 2026 . T <*> 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 X 2027 . A <*> 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 X 2028 . C <*> 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 X 2029 . T <*> 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 X 2030 . G <*> 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 X 2031 . C <*> 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 X 2032 . C <*> 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 X 2033 . A <*> 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 X 2034 . T <*> 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 X 2035 . T <*> 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 X 2036 . T <*> 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 X 2037 . T <*> 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 X 2038 . C <*> 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 X 2039 . A <*> 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 X 2040 . C <*> 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 X 2041 . G A,<*> 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 X 2042 . G <*> 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 X 2043 . G <*> 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 X 2044 . C <*> 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 X 2045 . A <*> 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 X 2046 . T <*> 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 X 2047 . G <*> 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 X 2048 . A <*> 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 X 2049 . A <*> 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 X 2050 . A <*> 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 X 2051 . T <*> 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 X 2052 . G <*> 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 X 2053 . G T,<*> 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 X 2054 . A <*> 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 X 2055 . G <*> 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 X 2056 . A <*> 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 X 2057 . T <*> 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 X 2058 . A <*> 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 X 2059 . A <*> 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 X 2060 . C <*> 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 X 2061 . A <*> 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 X 2062 . A <*> 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 X 2063 . C <*> 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 X 2064 . A <*> 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 X 2065 . G <*> 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 X 2066 . G <*> 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 X 2067 . A <*> 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 X 2068 . G <*> 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 X 2069 . C <*> 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 X 2070 . G <*> 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 X 2071 . A <*> 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 X 2072 . C <*> 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 X 2073 . C <*> 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 X 2074 . G <*> 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 X 2075 . C <*> 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 X 2076 . A <*> 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 X 2077 . C <*> 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 X 2078 . A <*> 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 X 2079 . G <*> 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 X 2080 . G <*> 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 X 2081 . C <*> 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 X 2082 . T <*> 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 X 2083 . G <*> 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 X 2084 . C <*> 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 X 2085 . T <*> 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 X 2086 . G <*> 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 X 2087 . A <*> 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 X 2088 . G <*> 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 X 2089 . C <*> 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 X 2090 . G <*> 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 X 2091 . C <*> 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 X 2092 . G <*> 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 X 2093 . T G,<*> 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 X 2094 . C <*> 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 X 2095 . A <*> 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 X 2096 . C <*> 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 X 2097 . A <*> 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 X 2098 . C <*> 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 X 2099 . G <*> 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 X 2100 . C <*> 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 X 2101 . A <*> 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 X 2102 . G <*> 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 X 2103 . C <*> 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 X 2104 . C <*> 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 X 2105 . A <*> 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 X 2106 . T <*> 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 X 2107 . C <*> 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 X 2108 . G <*> 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 X 2109 . C <*> 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 X 2110 . G <*> 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 X 2111 . C <*> 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 X 2112 . A <*> 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 X 2113 . G <*> 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 X 2114 . C <*> 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 X 2115 . T <*> 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 X 2116 . C <*> 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 X 2117 . A <*> 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 X 2118 . G <*> 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 X 2119 . G <*> 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 X 2120 . G <*> 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 X 2121 . A <*> 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 X 2122 . T <*> 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 X 2123 . A <*> 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 X 2124 . T <*> 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 X 2125 . T <*> 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 X 2126 . A <*> 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 X 2127 . C <*> 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 X 2128 . G <*> 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 X 2129 . T <*> 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 X 2130 . G <*> 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 X 2131 . T <*> 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 X 2132 . A <*> 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 X 2133 . A <*> 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 X 2134 . C <*> 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 X 2135 . T <*> 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 X 2136 . C <*> 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 X 2137 . G <*> 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 X 2138 . A <*> 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 X 2139 . C <*> 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 X 2140 . A <*> 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 X 2141 . T <*> 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 X 2142 . G <*> 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 X 2143 . T <*> 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 X 2144 . C <*> 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 X 2145 . A <*> 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 X 2146 . G <*> 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 X 2147 . C <*> 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 X 2148 . G <*> 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 X 2149 . A <*> 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 X 2150 . T <*> 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 X 2151 . T <*> 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 X 2152 . G <*> 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 X 2153 . T <*> 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 X 2154 . C <*> 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 X 2155 . A <*> 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 X 2156 . C <*> 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 X 2157 . A <*> 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 X 2158 . G <*> 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 X 2159 . G <*> 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 X 2160 . C <*> 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 X 2161 . A <*> 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 X 2162 . C <*> 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 X 2163 . T <*> 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 X 2164 . G <*> 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 X 2165 . C <*> 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 X 2166 . T <*> 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 X 2167 . A <*> 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 X 2168 . C <*> 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 X 2169 . T <*> 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 X 2170 . C <*> 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 X 2171 . C <*> 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 X 2172 . T <*> 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 X 2173 . G <*> 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 X 2174 . G <*> 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 X 2175 . G <*> 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 X 2176 . G <*> 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 X 2177 . T <*> 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 X 2178 . T <*> 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 X 2179 . T <*> 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 X 2180 . T <*> 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 X 2181 . C <*> 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 X 2182 . C <*> 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 X 2183 . A <*> 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 X 2184 . T <*> 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 X 2185 . C <*> 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 X 2186 . A <*> 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 X 2187 . A <*> 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 X 2188 . A <*> 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 X 2189 . C <*> 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 X 2190 . C <*> 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 X 2191 . C <*> 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 X 2192 . T <*> 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 X 2193 . C <*> 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 X 2194 . A <*> 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 X 2195 . A <*> 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 X 2196 . G <*> 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 X 2197 . A <*> 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 X 2198 . G <*> 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 X 2199 . C <*> 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 X 2200 . T <*> 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 X 2201 . G <*> 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 X 2202 . G <*> 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 X 2203 . G <*> 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 X 2204 . C <*> 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 X 2205 . C <*> 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 X 2206 . T <*> 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 X 2207 . G <*> 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 X 2208 . G <*> 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 X 2209 . G <*> 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 X 2210 . G C,<*> 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 X 2211 . T <*> 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 X 2212 . C <*> 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 X 2213 . A <*> 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 X 2214 . A <*> 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 X 2215 . C <*> 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 X 2216 . T <*> 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 X 2217 . T <*> 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 X 2218 . C <*> 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 X 2219 . C <*> 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 X 2220 . G A,<*> 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 X 2221 . G <*> 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 X 2222 . C <*> 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 X 2223 . C <*> 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 X 2224 . T <*> 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 X 2225 . G <*> 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 X 2226 . G <*> 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 X 2227 . G <*> 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 X 2228 . G C,<*> 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 X 2229 . A <*> 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 X 2230 . A <*> 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 X 2231 . A <*> 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 X 2232 . C <*> 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 X 2233 . T <*> 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 X 2234 . G <*> 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 X 2235 . G <*> 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 X 2236 . G <*> 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 X 2237 . G <*> 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 X 2238 . C <*> 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 X 2239 . A <*> 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 X 2240 . A <*> 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 X 2241 . G <*> 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 X 2242 . T <*> 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 X 2243 . A <*> 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 X 2244 . T <*> 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 X 2245 . C <*> 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 X 2246 . A <*> 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 X 2247 . C <*> 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 X 2248 . C <*> 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 X 2249 . A <*> 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 X 2250 . G <*> 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 X 2251 . A <*> 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 X 2252 . G <*> 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 X 2253 . A <*> 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 X 2254 . T <*> 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 X 2255 . G <*> 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 X 2256 . A <*> 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 X 2257 . G <*> 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 X 2258 . C <*> 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 X 2259 . T <*> 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 X 2260 . T <*> 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 X 2261 . T <*> 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 X 2262 . A <*> 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 X 2263 . T <*> 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 X 2264 . A <*> 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 X 2265 . A <*> 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 X 2266 . A <*> 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 X 2267 . A <*> 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 X 2268 . A <*> 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 X 2269 . T <*> 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 X 2270 . A <*> 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 X 2271 . A <*> 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 X 2272 . T <*> 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 X 2273 . G <*> 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 X 2274 . G <*> 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 X 2275 . T <*> 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 X 2276 . G <*> 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 X 2277 . C <*> 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 X 2278 . T <*> 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 X 2279 . A <*> 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 X 2280 . G <*> 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 X 2281 . C <*> 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 X 2282 . T <*> 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 X 2283 . G <*> 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 X 2284 . G <*> 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 X 2285 . G <*> 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 X 2286 . C <*> 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 X 2287 . A <*> 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 X 2288 . T <*> 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 X 2289 . G <*> 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 X 2290 . G <*> 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 X 2291 . T <*> 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 X 2292 . G <*> 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 X 2293 . G <*> 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 X 2294 . C <*> 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 X 2295 . T <*> 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 X 2296 . T <*> 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 X 2297 . G <*> 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 X 2298 . C <*> 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 X 2299 . A <*> 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 X 2300 . C <*> 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 X 2301 . C <*> 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 X 2302 . T <*> 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 X 2303 . G <*> 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 X 2304 . T <*> 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 X 2305 . A <*> 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 X 2306 . A <*> 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 X 2307 . T <*> 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 X 2308 . C <*> 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 X 2309 . C A,<*> 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 X 2310 . C <*> 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 X 2311 . A <*> 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 X 2312 . G <*> 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 X 2313 . C <*> 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 X 2314 . A <*> 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 X 2315 . C <*> 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 X 2316 . T <*> 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 X 2317 . T <*> 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 X 2318 . T <*> 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 X 2319 . G <*> 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 X 2320 . G <*> 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 X 2321 . G <*> 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 X 2322 . A <*> 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 X 2323 . G <*> 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 X 2324 . G <*> 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 X 2325 . C <*> 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 X 2326 . C <*> 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 X 2327 . G <*> 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 X 2328 . A <*> 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 X 2329 . G <*> 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 X 2330 . C <*> 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 X 2331 . T <*> 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 X 2332 . A <*> 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 X 2333 . G <*> 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 X 2334 . G <*> 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 X 2335 . A <*> 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 X 2336 . G <*> 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 X 2337 . G <*> 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 X 2338 . A <*> 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 X 2339 . T <*> 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 X 2340 . C <*> 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 X 2341 . G <*> 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 X 2342 . T <*> 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 X 2343 . T <*> 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 X 2344 . T <*> 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 X 2345 . G <*> 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 X 2346 . A <*> 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 X 2347 . G <*> 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 X 2348 . T <*> 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 X 2349 . C <*> 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 X 2350 . C <*> 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 X 2351 . A <*> 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 X 2352 . G <*> 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 X 2353 . C <*> 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 X 2354 . A <*> 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 X 2355 . G <*> 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 X 2356 . T <*> 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 X 2357 . T <*> 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 X 2358 . T <*> 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 X 2359 . G <*> 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 X 2360 . A <*> 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 X 2361 . G <*> 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 X 2362 . A <*> 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 X 2363 . C <*> 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 X 2364 . C <*> 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 X 2365 . A <*> 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 X 2366 . G <*> 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 X 2367 . C <*> 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 X 2368 . C <*> 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 X 2369 . T <*> 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 X 2370 . G <*> 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 X 2371 . G <*> 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 X 2372 . C <*> 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 X 2373 . C <*> 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 X 2374 . A <*> 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 X 2375 . A <*> 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 X 2376 . T <*> 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 X 2377 . A <*> 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 X 2378 . C <*> 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 X 2379 . G <*> 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 X 2380 . G <*> 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 X 2381 . C <*> 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 X 2382 . A <*> 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 X 2383 . A <*> 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 X 2384 . A <*> 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 X 2385 . A <*> 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 X 2386 . C <*> 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 X 2387 . C <*> 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 X 2388 . C <*> 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 X 2389 . A <*> 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 X 2390 . G <*> 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 X 2391 . T <*> 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 X 2392 . C <*> 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 X 2393 . T <*> 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 X 2394 . C <*> 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 X 2395 . T <*> 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 X 2396 . A <*> 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 X 2397 . C <*> 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 X 2398 . A <*> 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 X 2399 . A <*> 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 X 2400 . A <*> 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 X 2401 . A <*> 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 X 2402 . A <*> 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 X 2403 . A <*> 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 X 2404 . T <*> 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 X 2405 . A <*> 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 X 2406 . C <*> 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 X 2407 . A <*> 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 X 2408 . A <*> 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 X 2409 . A <*> 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 X 2410 . A <*> 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 X 2411 . A <*> 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 X 2412 . A <*> 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 X 2413 . C <*> 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 X 2414 . A <*> 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 X 2415 . A <*> 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 X 2416 . C <*> 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 X 2417 . T <*> 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 X 2418 . A <*> 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 X 2419 . G <*> 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 X 2420 . C <*> 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 X 2421 . C <*> 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 X 2422 . A <*> 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 X 2423 . G <*> 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 X 2424 . G <*> 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 X 2425 . C <*> 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 X 2426 . G <*> 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 X 2427 . T <*> 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 X 2428 . G <*> 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 X 2429 . G <*> 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 X 2430 . T A,<*> 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 X 2431 . G <*> 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 X 2432 . G <*> 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 X 2433 . T <*> 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 X 2434 . G <*> 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 X 2435 . C <*> 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 X 2436 . A <*> 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 X 2437 . C <*> 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 X 2438 . A <*> 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 X 2439 . C <*> 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 X 2440 . C <*> 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 X 2441 . T <*> 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 X 2442 . G <*> 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 X 2443 . T <*> 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 X 2444 . A <*> 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 X 2445 . G <*> 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 X 2446 . T <*> 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 X 2447 . C <*> 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 X 2448 . C <*> 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 X 2449 . C <*> 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 X 2450 . A <*> 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 X 2451 . G <*> 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 X 2452 . C <*> 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 X 2453 . T <*> 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 X 2454 . A <*> 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 X 2455 . C <*> 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 X 2456 . T <*> 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 X 2457 . C <*> 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 X 2458 . A <*> 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 X 2459 . G T,<*> 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 X 2460 . G <*> 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 X 2461 . A G,<*> 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 X 2462 . G <*> 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 X 2463 . G T,<*> 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 X 2464 . C <*> 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 X 2465 . T <*> 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 X 2466 . G <*> 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 X 2467 . A <*> 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 X 2468 . G <*> 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 X 2469 . G <*> 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 X 2470 . G <*> 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 X 2471 . G <*> 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 X 2472 . G <*> 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 X 2473 . A <*> 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 X 2474 . A <*> 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 X 2475 . G <*> 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 X 2476 . G <*> 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 X 2477 . A <*> 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 X 2478 . C <*> 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 X 2479 . T <*> 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 X 2480 . G <*> 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 X 2481 . C <*> 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 X 2482 . T <*> 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 X 2483 . T <*> 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 X 2484 . G <*> 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 X 2485 . A T,<*> 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 X 2486 . G <*> 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 X 2487 . C <*> 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 X 2488 . C <*> 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 X 2489 . C <*> 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 X 2490 . A <*> 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 X 2491 . G <*> 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 X 2492 . G A,<*> 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 X 2493 . A G,<*> 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 X 2494 . G <*> 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 X 2495 . T <*> 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 X 2496 . T <*> 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 X 2497 . T <*> 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 X 2498 . G <*> 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 X 2499 . A <*> 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 X 2500 . G <*> 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 X 2501 . G <*> 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 X 2502 . C <*> 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 X 2503 . T <*> 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 X 2504 . G <*> 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 X 2505 . C <*> 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 X 2506 . T <*> 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 X 2507 . G <*> 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 X 2508 . T <*> 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 X 2509 . G T,<*> 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 X 2510 . A <*> 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 X 2511 . G <*> 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 X 2512 . C <*> 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 X 2513 . T <*> 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 X 2514 . G <*> 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 X 2515 . T <*> 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 X 2516 . G <*> 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 X 2517 . A <*> 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 X 2518 . T <*> 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 X 2519 . C <*> 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 X 2520 . G <*> 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 X 2521 . C <*> 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 X 2522 . A <*> 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 X 2523 . T <*> 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 X 2524 . C <*> 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 X 2525 . A C,<*> 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 X 2526 . C <*> 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 X 2527 . T <*> 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 X 2528 . G <*> 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 X 2529 . C <*> 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 X 2530 . A <*> 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 X 2531 . T <*> 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 X 2532 . T <*> 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 X 2533 . C <*> 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 X 2534 . C <*> 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 X 2535 . A <*> 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 X 2536 . G <*> 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 X 2537 . C <*> 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 X 2538 . C <*> 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 X 2539 . C <*> 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 X 2540 . G <*> 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 X 2541 . G <*> 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 X 2542 . T <*> 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 X 2543 . G <*> 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 X 2544 . A <*> 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 X 2545 . C <*> 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 X 2546 . A <*> 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 X 2547 . G <*> 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 X 2548 . A <*> 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 X 2549 . G <*> 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 X 2550 . T <*> 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 X 2551 . G <*> 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 X 2552 . A <*> 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 X 2553 . G <*> 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 X 2554 . T <*> 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 X 2555 . C <*> 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 X 2556 . A <*> 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 X 2557 . C <*> 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 X 2558 . T <*> 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 X 2559 . G <*> 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 X 2560 . T <*> 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 X 2561 . C <*> 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 X 2562 . T <*> 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 X 2563 . C <*> 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 X 2564 . A G,<*> 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 X 2565 . A <*> 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 X 2566 . A <*> 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 X 2567 . A <*> 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 X 2568 . A <*> 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 X 2569 . A <*> 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 X 2570 . G <*> 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 X 2571 . A <*> 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 X 2572 . A <*> 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 X 2573 . A <*> 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 X 2574 . G <*> 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 X 2575 . G <*> 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 X 2576 . A <*> 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 X 2577 . A <*> 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 X 2578 . G <*> 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 X 2579 . A <*> 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 X 2580 . A <*> 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 X 2581 . A <*> 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 X 2582 . T <*> 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 X 2583 . A <*> 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 X 2584 . A <*> 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 X 2585 . A <*> 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 X 2586 . G <*> 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 X 2587 . A <*> 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 X 2588 . A <*> 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 X 2589 . A <*> 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 X 2590 . A <*> 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 X 2591 . C <*> 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 X 2592 . A <*> 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 X 2593 . A <*> 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 X 2594 . A <*> 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 X 2595 . T <*> 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 X 2596 . A <*> 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 X 2597 . A <*> 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 X 2598 . A <*> 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 X 2599 . A <*> 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 X 2600 . A <*> 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 X 2601 . T <*> 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 X 2602 . A <*> 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 X 2603 . A <*> 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 X 2604 . T <*> 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 X 2605 . A <*> 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 X 2606 . G <*> 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 X 2607 . T <*> 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 X 2608 . G <*> 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 X 2609 . C <*> 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 X 2610 . A <*> 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 X 2611 . G <*> 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 X 2612 . A <*> 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 X 2613 . C <*> 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 X 2614 . A <*> 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 X 2615 . A <*> 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 X 2616 . A <*> 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 X 2617 . A <*> 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 X 2618 . G <*> 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 X 2619 . G <*> 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 X 2620 . C <*> 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 X 2621 . C <*> 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 X 2622 . T <*> 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 X 2623 . T <*> 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 X 2624 . G <*> 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 X 2625 . A <*> 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 X 2626 . C <*> 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 X 2627 . C <*> 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 X 2628 . C <*> 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 X 2629 . A <*> 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 X 2630 . T <*> 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 X 2631 . C <*> 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 X 2632 . T <*> 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 X 2633 . A <*> 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 X 2634 . G <*> 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 X 2635 . C <*> 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 X 2636 . T <*> 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 X 2637 . T <*> 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 X 2638 . T <*> 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 X 2639 . G <*> 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 X 2640 . G <*> 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 X 2641 . C <*> 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 X 2642 . C <*> 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 X 2643 . C <*> 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 X 2644 . T <*> 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 X 2645 . C <*> 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 X 2646 . A <*> 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 X 2647 . G <*> 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 X 2648 . C <*> 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 X 2649 . A <*> 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 X 2650 . T <*> 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 X 2651 . C <*> 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 X 2652 . A <*> 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 X 2653 . A <*> 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 X 2654 . C <*> 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 X 2655 . C <*> 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 X 2656 . G <*> 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 X 2657 . C <*> 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 X 2658 . T <*> 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 X 2659 . A <*> 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 X 2660 . G <*> 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 X 2661 . A <*> 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 X 2662 . T <*> 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 X 2663 . A <*> 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 X 2664 . C <*> 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 X 2665 . G <*> 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 X 2666 . T <*> 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 X 2667 . C <*> 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 X 2668 . C <*> 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 X 2669 . C <*> 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 X 2670 . T <*> 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 X 2671 . C <*> 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 X 2672 . C <*> 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 X 2673 . C <*> 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 X 2674 . T <*> 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 X 2675 . T <*> 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 X 2676 . T <*> 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 X 2677 . C <*> 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 X 2678 . T <*> 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 X 2679 . T <*> 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 X 2680 . C <*> 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 X 2681 . T <*> 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 X 2682 . G <*> 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 X 2683 . G <*> 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 X 2684 . G <*> 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 X 2685 . G <*> 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 X 2686 . C <*> 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 X 2687 . A <*> 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 X 2688 . C <*> 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 X 2689 . A <*> 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 X 2690 . G <*> 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 X 2691 . G <*> 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 X 2692 . T <*> 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 X 2693 . C <*> 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 X 2694 . A <*> 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 X 2695 . C <*> 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 X 2696 . A <*> 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 X 2697 . C <*> 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 X 2698 . T <*> 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 X 2699 . C <*> 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 X 2700 . T <*> 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 X 2701 . C <*> 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 X 2702 . T <*> 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 X 2703 . T <*> 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 X 2704 . C <*> 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 X 2705 . C <*> 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 X 2706 . A <*> 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 X 2707 . G <*> 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 X 2708 . G <*> 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 X 2709 . T <*> 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 X 2710 . C <*> 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 X 2711 . T <*> 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 X 2712 . A <*> 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 X 2713 . G T,<*> 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 X 2714 . G <*> 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 X 2715 . A <*> 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 X 2716 . T <*> 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 X 2717 . G <*> 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 X 2718 . C <*> 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 X 2719 . A <*> 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 X 2720 . G <*> 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 X 2721 . C <*> 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 X 2722 . T <*> 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 X 2723 . G <*> 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 X 2724 . A <*> 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 X 2725 . G <*> 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 X 2726 . G <*> 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 X 2727 . G <*> 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 X 2728 . G <*> 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 X 2729 . T <*> 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 X 2730 . G <*> 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 X 2731 . C <*> 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 X 2732 . C <*> 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 X 2733 . C A,<*> 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 X 2734 . C <*> 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 X 2735 . T <*> 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 X 2736 . C <*> 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 X 2737 . T <*> 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 X 2738 . T <*> 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 X 2739 . A <*> 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 X 2740 . C <*> 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 X 2741 . C <*> 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 X 2742 . A <*> 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 X 2743 . T <*> 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 X 2744 . C <*> 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 X 2745 . T <*> 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 X 2746 . A <*> 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 X 2747 . A <*> 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 X 2748 . T <*> 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 X 2749 . C <*> 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 X 2750 . T <*> 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 X 2751 . G <*> 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 X 2752 . T <*> 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 X 2753 . G <*> 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 X 2754 . C <*> 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 X 2755 . C <*> 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 X 2756 . C <*> 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 X 2757 . T <*> 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 X 2758 . T <*> 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 X 2759 . A <*> 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 X 2760 . T <*> 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 X 2761 . T <*> 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 X 2762 . T <*> 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 X 2763 . C A,<*> 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 X 2764 . C <*> 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 X 2765 . T <*> 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 X 2766 . C <*> 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 X 2767 . T <*> 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 X 2768 . G <*> 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 X 2769 . C <*> 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 X 2770 . T <*> 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 X 2771 . T <*> 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 X 2772 . T <*> 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 X 2773 . A <*> 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 X 2774 . G <*> 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 X 2775 . T <*> 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 X 2776 . G <*> 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 X 2777 . A <*> 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 X 2778 . G <*> 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 X 2779 . G <*> 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 X 2780 . A <*> 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 X 2781 . A <*> 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 X 2782 . G <*> 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 X 2783 . A <*> 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 X 2784 . G <*> 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 X 2785 . G <*> 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 X 2786 . C <*> 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 X 2787 . C <*> 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 X 2788 . C <*> 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 X 2789 . C <*> 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 X 2790 . T <*> 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 X 2791 . G <*> 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 X 2792 . G <*> 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 X 2793 . T <*> 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 X 2794 . C <*> 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 X 2795 . C <*> 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 X 2796 . A <*> 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 X 2797 . T <*> 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 X 2798 . G <*> 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 X 2799 . A <*> 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 X 2800 . A <*> 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 X 2801 . G <*> 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 X 2802 . G <*> 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 X 2803 . G <*> 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 X 2804 . G <*> 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 X 2805 . C <*> 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 X 2806 . C <*> 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 X 2807 . T <*> 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 X 2808 . T <*> 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 X 2809 . T <*> 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 X 2810 . C <*> 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 X 2811 . A <*> 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 X 2812 . G <*> 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 X 2813 . A <*> 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 X 2814 . G <*> 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 X 2815 . A <*> 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 X 2816 . C <*> 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 X 2817 . G <*> 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 X 2818 . G <*> 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 X 2819 . G <*> 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 X 2820 . G <*> 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 X 2821 . A <*> 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 X 2822 . C <*> 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 X 2823 . C <*> 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 X 2824 . C <*> 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 X 2825 . C <*> 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 X 2826 . T <*> 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 X 2827 . G <*> 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 X 2828 . A <*> 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 X 2829 . G <*> 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 X 2830 . G <*> 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 X 2831 . A <*> 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 X 2832 . G <*> 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 X 2833 . C <*> 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 X 2834 . C <*> 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 X 2835 . C <*> 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 X 2836 . C <*> 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 X 2837 . G <*> 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 X 2838 . A <*> 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 X 2839 . G <*> 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 X 2840 . C <*> 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 X 2841 . A <*> 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 X 2842 . G <*> 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 X 2843 . C <*> 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 X 2844 . A <*> 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 X 2845 . G <*> 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 X 2846 . C <*> 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 X 2847 . C <*> 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 X 2848 . G <*> 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 X 2849 . T <*> 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 X 2850 . C <*> 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 X 2851 . G <*> 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 X 2852 . T <*> 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 X 2853 . G <*> 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 X 2854 . T <*> 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 X 2855 . C <*> 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 X 2856 . T <*> 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 X 2857 . C <*> 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 X 2858 . A <*> 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 X 2859 . C <*> 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 X 2860 . C <*> 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 X 2861 . C <*> 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 X 2862 . A <*> 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 X 2863 . G <*> 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 X 2864 . G <*> 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 X 2865 . G <*> 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 X 2866 . T <*> 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 X 2867 . G <*> 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 X 2868 . T <*> 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 X 2869 . C <*> 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 X 2870 . T <*> 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 X 2871 . G <*> 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 X 2872 . A <*> 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 X 2873 . A <*> 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 X 2874 . A <*> 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 X 2875 . C <*> 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 X 2876 . A <*> 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 X 2877 . G <*> 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 X 2878 . A <*> 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 X 2879 . T <*> 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 X 2880 . G <*> 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 X 2881 . T <*> 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 X 2882 . G <*> 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 X 2883 . G <*> 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 X 2884 . A <*> 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 X 2885 . G <*> 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 X 2886 . G A,<*> 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 X 2887 . T <*> 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 X 2888 . C <*> 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 X 2889 . T <*> 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 X 2890 . C <*> 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 X 2891 . G <*> 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 X 2892 . G <*> 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 X 2893 . G <*> 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 X 2894 . T <*> 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 X 2895 . G <*> 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 X 2896 . A <*> 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 X 2897 . G <*> 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 X 2898 . G <*> 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 X 2899 . C <*> 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 X 2900 . G <*> 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 X 2901 . T <*> 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 X 2902 . G <*> 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 X 2903 . G <*> 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 X 2904 . C <*> 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 X 2905 . T <*> 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 X 2906 . C <*> 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 X 2907 . A <*> 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 X 2908 . G <*> 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 X 2909 . A <*> 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 X 2910 . T <*> 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 X 2911 . A <*> 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 X 2912 . C <*> 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 X 2913 . A <*> 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 X 2914 . G <*> 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 X 2915 . G <*> 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 X 2916 . G <*> 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 X 2917 . A <*> 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 X 2918 . G <*> 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 X 2919 . T <*> 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 X 2920 . G <*> 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 X 2921 . G <*> 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 X 2922 . C <*> 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 X 2923 . C <*> 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 X 2924 . C <*> 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 X 2925 . A <*> 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 X 2926 . C <*> 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 X 2927 . A <*> 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 X 2928 . G <*> 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 X 2929 . C <*> 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 X 2930 . T <*> 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 X 2931 . C <*> 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 X 2932 . G <*> 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 X 2933 . G <*> 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 X 2934 . C <*> 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 X 2935 . C <*> 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 X 2936 . T <*> 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 X 2937 . G <*> 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 X 2938 . T <*> 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 X 2939 . C <*> 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 X 2940 . T <*> 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 X 2941 . T <*> 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 X 2942 . T <*> 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 X 2943 . G <*> 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 X 2944 . A <*> 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 X 2945 . A <*> 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 X 2946 . A <*> 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 X 2947 . G <*> 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 X 2948 . G <*> 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 X 2949 . C <*> 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 X 2950 . C <*> 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 X 2951 . A <*> 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 X 2952 . C <*> 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 X 2953 . G <*> 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 X 2954 . T <*> 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 X 2955 . G <*> 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 X 2956 . A <*> 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 X 2957 . C <*> 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 X 2958 . C <*> 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 X 2959 . T <*> 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 X 2960 . G <*> 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 X 2961 . G <*> 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 X 2962 . C <*> 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 X 2963 . C <*> 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 X 2964 . C <*> 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 X 2965 . A <*> 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 X 2966 . C <*> 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 X 2967 . G <*> 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 X 2968 . G <*> 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 X 2969 . C <*> 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 X 2970 . T <*> 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 X 2971 . G <*> 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 X 2972 . G <*> 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 X 2973 . C <*> 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 X 2974 . A <*> 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 X 2975 . G <*> 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 X 2976 . G <*> 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 X 2977 . T <*> 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 X 2978 . G <*> 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 X 2979 . G <*> 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 X 2980 . G <*> 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 X 2981 . A <*> 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 X 2982 . C <*> 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 X 2983 . C <*> 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 X 2984 . C <*> 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 X 2985 . A <*> 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 X 2986 . G <*> 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 X 2987 . C <*> 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 X 2988 . T <*> 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 X 2989 . G <*> 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 X 2990 . C <*> 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 X 2991 . A <*> 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 X 2992 . G <*> 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 X 2993 . G <*> 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 X 2994 . G <*> 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 X 2995 . G <*> 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 X 2996 . T <*> 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 X 2997 . C <*> 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 X 2998 . C <*> 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 X 2999 . A <*> 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 X 3000 . G <*> 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 X 3001 . C <*> 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 X 3002 . A <*> 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 X 3003 . G <*> 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 X 3004 . C <*> 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 X 3005 . A <*> 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 X 3006 . C <*> 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 X 3007 . C <*> 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 X 3008 . C <*> 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 X 3009 . A <*> 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 X 3010 . C <*> 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 X 3011 . A <*> 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 X 3012 . G <*> 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 X 3013 . C <*> 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 X 3014 . A <*> 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 X 3015 . G <*> 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 X 3016 . C <*> 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 X 3017 . C A,<*> 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 X 3018 . A <*> 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 X 3019 . C <*> 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 X 3020 . C <*> 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 X 3021 . T <*> 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 X 3022 . G <*> 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 X 3023 . T G,<*> 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 X 3024 . G <*> 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 X 3025 . G <*> 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 X 3026 . C <*> 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 X 3027 . A <*> 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 X 3028 . G <*> 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 X 3029 . G <*> 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 X 3030 . G <*> 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 X 3031 . A <*> 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 X 3032 . G <*> 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 X 3033 . G <*> 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 X 3034 . A <*> 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 X 3035 . G <*> 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 X 3036 . C <*> 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 X 3037 . T <*> 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 X 3038 . T <*> 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 X 3039 . G <*> 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 X 3040 . T <*> 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 X 3041 . G <*> 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 X 3042 . G <*> 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 X 3043 . T <*> 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 X 3044 . A C,<*> 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 X 3045 . C <*> 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 X 3046 . A <*> 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 X 3047 . G <*> 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 X 3048 . T <*> 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 X 3049 . G <*> 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 X 3050 . G <*> 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 X 3051 . A <*> 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 X 3052 . C <*> 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 X 3053 . A <*> 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 X 3054 . G <*> 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 X 3055 . G <*> 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 X 3056 . C <*> 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 X 3057 . C <*> 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 X 3058 . C <*> 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 X 3059 . T G,<*> 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 X 3060 . G <*> 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 X 3061 . C <*> 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 X 3062 . C <*> 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 X 3063 . C <*> 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 X 3064 . A <*> 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 X 3065 . G <*> 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 X 3066 . A <*> 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 X 3067 . T <*> 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 X 3068 . G <*> 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 X 3069 . G <*> 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 X 3070 . C <*> 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 X 3071 . C <*> 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 X 3072 . C <*> 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 X 3073 . C <*> 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 X 3074 . C <*> 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 X 3075 . C <*> 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 X 3076 . G <*> 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 X 3077 . C <*> 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 X 3078 . C <*> 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 X 3079 . T <*> 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 X 3080 . G <*> 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 X 3081 . C <*> 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 X 3082 . C <*> 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 X 3083 . T C,<*> 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 X 3084 . G <*> 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 X 3085 . T <*> 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 X 3086 . G <*> 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 X 3087 . G <*> 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 X 3088 . A <*> 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 X 3089 . A <*> 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 X 3090 . G <*> 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 X 3091 . T <*> 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 X 3092 . T <*> 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 X 3093 . G <*> 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 X 3094 . A <*> 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 X 3095 . C <*> 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 X 3096 . C <*> 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 X 3097 . A <*> 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 X 3098 . G <*> 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 X 3099 . A <*> 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 X 3100 . C <*> 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 X 3101 . C <*> 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 X 3102 . A <*> 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 X 3103 . T <*> 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 X 3104 . C T,<*> 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 X 3105 . T <*> 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 X 3106 . G <*> 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 X 3107 . T <*> 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 X 3108 . C <*> 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 X 3109 . A <*> 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 X 3110 . C <*> 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 X 3111 . A <*> 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 X 3112 . G <*> 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 X 3113 . C <*> 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 X 3114 . A <*> 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 X 3115 . G <*> 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 X 3116 . G <*> 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 X 3117 . T <*> 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 X 3118 . A <*> 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 X 3119 . A <*> 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 X 3120 . G <*> 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 X 3121 . A <*> 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 X 3122 . C <*> 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 X 3123 . T <*> 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 X 3124 . C <*> 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 X 3125 . T <*> 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 X 3126 . G <*> 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 X 3127 . C <*> 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 X 3128 . T <*> 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 X 3129 . T <*> 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 X 3130 . T <*> 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 X 3131 . C <*> 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 X 3132 . T <*> 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 X 3133 . G <*> 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 X 3134 . G <*> 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 X 3135 . G <*> 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 X 3136 . C <*> 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 X 3137 . A <*> 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 X 3138 . A <*> 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 X 3139 . C <*> 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 X 3140 . C <*> 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 X 3141 . C <*> 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 X 3142 . A <*> 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 X 3143 . G <*> 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 X 3144 . C <*> 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 X 3145 . A <*> 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 X 3146 . G <*> 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 X 3147 . G <*> 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 X 3148 . T <*> 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 X 3149 . G <*> 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 X 3150 . A <*> 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 X 3151 . C <*> 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 X 3152 . C <*> 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 X 3153 . C <*> 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 X 3154 . T <*> 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 X 3155 . G <*> 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 X 3156 . G <*> 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 X 3157 . A <*> 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 X 3158 . A <*> 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 X 3159 . T <*> 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 X 3160 . T <*> 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 X 3161 . C <*> 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 X 3162 . C <*> 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 X 3163 . T A,<*> 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 X 3164 . G <*> 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 X 3165 . T <*> 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 X 3166 . C <*> 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 X 3167 . C <*> 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 X 3168 . A <*> 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 X 3169 . T <*> 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 X 3170 . C <*> 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 X 3171 . T <*> 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 X 3172 . G <*> 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 X 3173 . G <*> 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 X 3174 . C <*> 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 X 3175 . A <*> 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 X 3176 . G <*> 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 X 3177 . G <*> 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 X 3178 . T <*> 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 X 3179 . G <*> 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 X 3180 . G <*> 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 X 3181 . G <*> 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 X 3182 . C <*> 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 X 3183 . A <*> 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 X 3184 . T <*> 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 X 3185 . T <*> 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 X 3186 . G <*> 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 X 3187 . A <*> 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 X 3188 . A <*> 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 X 3189 . A <*> 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 X 3190 . C <*> 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 X 3191 . T <*> 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 X 3192 . G <*> 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 X 3193 . G <*> 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 X 3194 . T C,<*> 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 X 3195 . T <*> 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 X 3196 . T <*> 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 X 3197 . A <*> 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 X 3198 . A <*> 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 X 3199 . A <*> 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 X 3200 . A <*> 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 X 3201 . A <*> 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 X 3202 . T <*> 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 X 3203 . G A,<*> 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 X 3204 . T <*> 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 X 3205 . C <*> 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 X 3206 . A <*> 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 X 3207 . C <*> 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 X 3208 . A <*> 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 X 3209 . C <*> 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 X 3210 . C <*> 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 X 3211 . A <*> 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 X 3212 . T <*> 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 X 3213 . A <*> 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 X 3214 . G <*> 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 X 3215 . G <*> 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 X 3216 . C <*> 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 X 3217 . C <*> 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 X 3218 . G C,<*> 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 X 3219 . G A,<*> 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 X 3220 . G <*> 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 X 3221 . C <*> 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 X 3222 . A <*> 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 X 3223 . C <*> 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 X 3224 . A <*> 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 X 3225 . G <*> 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 X 3226 . T <*> 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 X 3227 . G <*> 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 X 3228 . G <*> 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 X 3229 . C <*> 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 X 3230 . T <*> 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 X 3231 . C <*> 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 X 3232 . A <*> 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 X 3233 . C <*> 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 X 3234 . G T,<*> 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 X 3235 . C <*> 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 X 3236 . C <*> 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 X 3237 . T <*> 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 X 3238 . G <*> 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 X 3239 . T <*> 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 X 3240 . A <*> 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 X 3241 . A <*> 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 X 3242 . T <*> 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 X 3243 . C <*> 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 X 3244 . C <*> 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 X 3245 . C <*> 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 X 3246 . A <*> 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 X 3247 . G <*> 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 X 3248 . C <*> 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 X 3249 . C <*> 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 X 3250 . C <*> 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 X 3251 . T <*> 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 X 3252 . T <*> 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 X 3253 . T <*> 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 X 3254 . G <*> 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 X 3255 . G <*> 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 X 3256 . G <*> 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 X 3257 . A <*> 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 X 3258 . G <*> 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 X 3259 . G <*> 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 X 3260 . C <*> 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 X 3261 . C <*> 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 X 3262 . A <*> 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 X 3263 . G <*> 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 X 3264 . G <*> 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 X 3265 . G <*> 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 X 3266 . T <*> 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 X 3267 . G <*> 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 X 3268 . G <*> 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 X 3269 . G <*> 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 X 3270 . T <*> 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 X 3271 . G <*> 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 X 3272 . G <*> 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 X 3273 . A <*> 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 X 3274 . T <*> 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 X 3275 . C <*> 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 X 3276 . A <*> 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 X 3277 . C <*> 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 X 3278 . T <*> 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 X 3279 . T <*> 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 X 3280 . G <*> 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 X 3281 . A <*> 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 X 3282 . G <*> 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 X 3283 . G <*> 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 X 3284 . T <*> 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 X 3285 . C <*> 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 X 3286 . A <*> 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 X 3287 . G <*> 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 X 3288 . G <*> 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 X 3289 . A <*> 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 X 3290 . G <*> 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 X 3291 . T <*> 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 X 3292 . T <*> 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 X 3293 . C <*> 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 X 3294 . A <*> 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 X 3295 . A <*> 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 X 3296 . G <*> 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 X 3297 . A <*> 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 X 3298 . C <*> 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 X 3299 . C <*> 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 X 3300 . A <*> 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 X 3301 . G <*> 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 X 3302 . C <*> 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 X 3303 . C <*> 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 X 3304 . T <*> 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 X 3305 . G <*> 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 X 3306 . G <*> 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 X 3307 . C <*> 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 X 3308 . C <*> 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 X 3309 . A <*> 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 X 3310 . A <*> 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 X 3311 . C <*> 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 X 3312 . A <*> 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 X 3313 . T <*> 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 X 3314 . G <*> 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 X 3315 . G <*> 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 X 3316 . T <*> 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 X 3317 . G <*> 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 X 3318 . A <*> 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 X 3319 . A <*> 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 X 3320 . A <*> 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 X 3321 . C <*> 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 X 3322 . C <*> 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 X 3323 . C <*> 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 X 3324 . C <*> 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 X 3325 . G <*> 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 X 3326 . T <*> 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 X 3327 . C <*> 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 X 3328 . T <*> 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 X 3329 . A <*> 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 X 3330 . C <*> 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 X 3331 . T <*> 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 X 3332 . A <*> 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 X 3333 . A <*> 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 X 3334 . A <*> 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 X 3335 . A <*> 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 X 3336 . A <*> 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 X 3337 . T <*> 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 X 3338 . A <*> 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 X 3339 . C <*> 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 X 3340 . A <*> 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 X 3341 . A <*> 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 X 3342 . A <*> 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 X 3343 . A <*> 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 X 3344 . A <*> 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 X 3345 . T <*> 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 X 3346 . T <*> 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 X 3347 . A <*> 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 X 3348 . G <*> 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 X 3349 . C <*> 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 X 3350 . C <*> 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 X 3351 . T <*> 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 X 3352 . G <*> 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 X 3353 . G <*> 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 X 3354 . C <*> 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 X 3355 . G <*> 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 X 3356 . T <*> 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 X 3357 . G <*> 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 X 3358 . G <*> 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 X 3359 . T <*> 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 X 3360 . G <*> 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 X 3361 . G <*> 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 X 3362 . C <*> 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 X 3363 . G <*> 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 X 3364 . C <*> 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 X 3365 . A <*> 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 X 3366 . T <*> 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 X 3367 . G <*> 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 X 3368 . C <*> 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 X 3369 . C <*> 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 X 3370 . T <*> 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 X 3371 . G <*> 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 X 3372 . T <*> 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 X 3373 . A <*> 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 X 3374 . A <*> 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 X 3375 . T <*> 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 X 3376 . C <*> 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 X 3377 . C <*> 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 X 3378 . C <*> 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 X 3379 . A <*> 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 X 3380 . G <*> 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 X 3381 . C <*> 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 X 3382 . T <*> 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 X 3383 . A <*> 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 X 3384 . C <*> 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 X 3385 . T <*> 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 X 3386 . T <*> 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 X 3387 . G <*> 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 X 3388 . G <*> 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 X 3389 . G <*> 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 X 3390 . A <*> 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 X 3391 . A <*> 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 X 3392 . G <*> 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 X 3393 . C <*> 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 X 3394 . T <*> 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 X 3395 . G <*> 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 X 3396 . A <*> 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 X 3397 . G <*> 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 X 3398 . G <*> 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 X 3399 . G <*> 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 X 3400 . A <*> 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 X 3401 . T <*> 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 X 3402 . G <*> 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 X 3403 . A <*> 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 X 3404 . G <*> 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 X 3405 . A <*> 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 X 3406 . A <*> 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 X 3407 . C <*> 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 X 3408 . T <*> 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 X 3409 . G <*> 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 X 3410 . C <*> 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 X 3411 . T <*> 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 X 3412 . T <*> 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 X 3413 . G <*> 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 X 3414 . A <*> 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 X 3415 . A <*> 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 X 3416 . C <*> 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 X 3417 . C <*> 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 X 3418 . T <*> 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 X 3419 . G <*> 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 X 3420 . G <*> 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 X 3421 . G <*> 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 X 3422 . A <*> 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 X 3423 . G <*> 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 X 3424 . G <*> 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 X 3425 . C <*> 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 X 3426 . A <*> 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 X 3427 . G <*> 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 X 3428 . A <*> 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 X 3429 . C <*> 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 X 3430 . G <*> 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 X 3431 . T <*> 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 X 3432 . T <*> 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 X 3433 . G <*> 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 X 3434 . C <*> 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 X 3435 . A <*> 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 X 3436 . G <*> 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 X 3437 . T G,<*> 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 X 3438 . G <*> 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 X 3439 . A <*> 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 X 3440 . G <*> 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 X 3441 . C <*> 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 X 3442 . T <*> 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 X 3443 . G <*> 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 X 3444 . A <*> 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 X 3445 . G <*> 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 X 3446 . A <*> 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 X 3447 . T <*> 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 X 3448 . C <*> 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 X 3449 . A <*> 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 X 3450 . C <*> 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 X 3451 . G <*> 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 X 3452 . C <*> 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 X 3453 . C <*> 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 X 3454 . A <*> 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 X 3455 . C <*> 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 X 3456 . T <*> 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 X 3457 . G <*> 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 X 3458 . C <*> 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 X 3459 . A C,<*> 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 X 3460 . C <*> 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 X 3461 . T <*> 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 X 3462 . C <*> 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 X 3463 . C <*> 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 X 3464 . A <*> 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 X 3465 . G <*> 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 X 3466 . C <*> 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 X 3467 . C <*> 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 X 3468 . T <*> 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 X 3469 . G <*> 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 X 3470 . G <*> 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 X 3471 . G <*> 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 X 3472 . C <*> 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 X 3473 . A <*> 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 X 3474 . A <*> 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 X 3475 . C <*> 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 X 3476 . A <*> 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 X 3477 . G <*> 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 X 3478 . A <*> 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 X 3479 . G <*> 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 X 3480 . T <*> 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 X 3481 . A <*> 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 X 3482 . A <*> 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 X 3483 . G <*> 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 X 3484 . A C,<*> 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 X 3485 . C <*> 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 X 3486 . T <*> 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 X 3487 . C <*> 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 X 3488 . T <*> 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 X 3489 . G <*> 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 X 3490 . T C,<*> 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 X 3491 . C <*> 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 X 3492 . T <*> 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 X 3493 . C <*> 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 X 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 X 3494 . A <*> 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 X 3495 . A <*> 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 X 3496 . A <*> 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 X 3497 . A <*> 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 X 3498 . A <*> 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 X 3499 . A <*> 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 X 3500 . A <*> 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 X 3501 . A <*> 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 X 3502 . A <*> 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 X 3503 . A <*> 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 X 3504 . A <*> 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 X 3505 . A <*> 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 X 3506 . A <*> 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 X 3507 . T <*> 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 X 3508 . C <*> 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 X 3509 . A <*> 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 X 3510 . C A,<*> 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 X 3511 . A <*> 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 X 3512 . C <*> 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 X 3513 . C A,<*> 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 X 3514 . A <*> 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 X 3515 . T <*> 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 X 3516 . T <*> 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 X 3517 . T <*> 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 X 3518 . T <*> 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 X 3519 . G <*> 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 X 3520 . G <*> 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 X 3521 . C <*> 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 X 3522 . T <*> 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 X 3523 . T <*> 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 X 3524 . C <*> 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 X 3525 . A <*> 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 X 3526 . G <*> 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 X 3527 . A <*> 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 X 3528 . T <*> 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 X 3529 . T <*> 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 X 3530 . G <*> 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 X 3531 . C A,<*> 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 X 3532 . A <*> 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 X 3533 . T <*> 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 X 3534 . A <*> 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 X 3535 . T <*> 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 X 3536 . C <*> 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 X 3537 . C <*> 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 X 3538 . T <*> 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 X 3539 . C <*> 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 X 3540 . C <*> 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 X 3541 . T <*> 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 X 3542 . G <*> 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 X 3543 . C <*> 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 X 3544 . A <*> 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 X 3545 . A <*> 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 X 3546 . G <*> 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 X 3547 . G <*> 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 X 3548 . A <*> 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 X 3549 . T <*> 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 X 3550 . A <*> 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 X 3551 . T <*> 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 X 3552 . A <*> 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 X 3553 . T A,<*> 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 X 3554 . A <*> 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 X 3555 . C <*> 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 X 3556 . G <*> 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 X 3557 . C <*> 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 X 3558 . G <*> 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 X 3559 . T <*> 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 X 3560 . G <*> 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 X 3561 . A <*> 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 X 3562 . A <*> 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 X 3563 . A <*> 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 X 3564 . T <*> 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 X 3565 . T <*> 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 X 3566 . C <*> 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 X 3567 . A <*> 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 X 3568 . A <*> 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 X 3569 . G <*> 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 X 3570 . T <*> 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 X 3571 . C <*> 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 X 3572 . A <*> 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 X 3573 . A <*> 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 X 3574 . T <*> 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 X 3575 . G <*> 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 X 3576 . A <*> 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 X 3577 . C <*> 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 X 3578 . A <*> 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 X 3579 . A <*> 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 X 3580 . A <*> 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 X 3581 . T <*> 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 X 3582 . C <*> 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 X 3583 . A <*> 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 X 3584 . G <*> 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 X 3585 . A <*> 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 X 3586 . A <*> 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 X 3587 . G A,<*> 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 X 3588 . A <*> 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 X 3589 . A <*> 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 X 3590 . A <*> 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 X 3591 . A <*> 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 X 3592 . A <*> 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 X 3593 . A <*> 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 X 3594 . C <*> 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 X 3595 . A <*> 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 X 3596 . T <*> 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 X 3597 . A <*> 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 X 3598 . T <*> 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 X 3599 . A <*> 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 X 3600 . T <*> 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 X 3601 . A <*> 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 X 3602 . T <*> 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 X 3603 . A <*> 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 X 3604 . C <*> 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 X 3605 . G <*> 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 X 3606 . C <*> 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 X 3607 . A <*> 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 X 3608 . A <*> 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 X 3609 . A <*> 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 X 3610 . C <*> 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 X 3611 . C <*> 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 X 3612 . A <*> 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 X 3613 . G <*> 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 X 3614 . T <*> 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 X 3615 . A <*> 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 X 3616 . T <*> 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 X 3617 . C <*> 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 X 3618 . C <*> 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 X 3619 . T <*> 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 X 3620 . A <*> 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 X 3621 . C <*> 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 X 3622 . T <*> 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 X 3623 . G <*> 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 X 3624 . T <*> 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 X 3625 . G <*> 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 X 3626 . T <*> 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 X 3627 . G <*> 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 X 3628 . T <*> 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 X 3629 . G <*> 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 X 3630 . T <*> 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 X 3631 . C <*> 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 X 3632 . G <*> 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 X 3633 . T <*> 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 X 3634 . T <*> 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 X 3635 . T <*> 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 X 3636 . G <*> 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 X 3637 . T <*> 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 X 3638 . T <*> 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 X 3639 . G <*> 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 X 3640 . T <*> 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 X 3641 . G <*> 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 X 3642 . T <*> 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 X 3643 . T <*> 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 X 3644 . T <*> 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 X 3645 . T <*> 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 X 3646 . C <*> 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 X 3647 . G <*> 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 X 3648 . A <*> 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 X 3649 . C <*> 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 X 3650 . A <*> 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 X 3651 . G <*> 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 X 3652 . C <*> 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 X 3653 . T <*> 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 X 3654 . G <*> 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 X 3655 . T <*> 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 X 3656 . C <*> 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 X 3657 . C <*> 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 X 3658 . G <*> 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 X 3659 . T <*> 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 X 3660 . G <*> 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 X 3661 . T <*> 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 X 3662 . T <*> 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 X 3663 . A <*> 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 X 3664 . T <*> 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 X 3665 . A <*> 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 X 3666 . A <*> 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 X 3667 . T <*> 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 X 3668 . A <*> 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 X 3669 . A <*> 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 X 3670 . T <*> 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 X 3671 . T <*> 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 X 3672 . C <*> 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 X 3673 . C <*> 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 X 3674 . T <*> 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 X 3675 . C <*> 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 X 3676 . T <*> 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 X 3677 . A <*> 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 X 3678 . G <*> 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 X 3679 . T <*> 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 X 3680 . T <*> 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 X 3681 . C <*> 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 X 3682 . A <*> 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 X 3683 . A <*> 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 X 3684 . A <*> 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 X 3685 . T <*> 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 X 3686 . T <*> 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 X 3687 . T <*> 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 X 3688 . A <*> 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 X 3689 . T <*> 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 X 3690 . T <*> 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 X 3691 . C <*> 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 X 3692 . A <*> 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 X 3693 . T <*> 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 X 3694 . T <*> 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 X 3695 . T <*> 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 X 3696 . T <*> 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 X 3697 . T <*> 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 X 3698 . A <*> 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 X 3699 . A <*> 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 X 3700 . C <*> 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 X 3701 . T <*> 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 X 3702 . T <*> 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 X 3703 . C <*> 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 X 3704 . A <*> 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 X 3705 . T <*> 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 X 3706 . A <*> 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 X 3707 . G <*> 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 X 3708 . T <*> 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 X 3709 . A <*> 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 X 3710 . C <*> 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 X 3711 . C <*> 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 X 3712 . A <*> 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 X 3713 . C <*> 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 X 3714 . A <*> 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 X 3715 . T <*> 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 X 3716 . T <*> 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 X 3717 . C <*> 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 X 3718 . T <*> 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 X 3719 . A <*> 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 X 3720 . C <*> 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 X 3721 . A <*> 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 X 3722 . C <*> 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 X 3723 . A <*> 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 X 3724 . C <*> 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 X 3725 . T <*> 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 X 3726 . G <*> 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 X 3727 . C <*> 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 X 3728 . C <*> 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 X 3729 . C <*> 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 X 3730 . A <*> 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 X 3731 . T <*> 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 X 3732 . G <*> 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 X 3733 . T <*> 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 X 3734 . C <*> 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 X 3735 . C <*> 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 X 3736 . C <*> 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 X 3737 . C <*> 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 X 3738 . T <*> 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 X 3739 . C <*> 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 X 3740 . A <*> 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 X 3741 . A <*> 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 X 3742 . G <*> 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 X 3743 . C <*> 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 X 3744 . T <*> 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 X 3745 . T <*> 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 X 3746 . C <*> 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 X 3747 . C <*> 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 X 3748 . C <*> 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 X 3749 . C <*> 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 X 3750 . T <*> 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 X 3751 . G <*> 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 X 3752 . G <*> 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 X 3753 . C <*> 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 X 3754 . T <*> 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 X 3755 . C <*> 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 X 3756 . C <*> 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 X 3757 . T <*> 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 X 3758 . G <*> 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 X 3759 . C <*> 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 X 3760 . A <*> 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 X 3761 . A <*> 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 X 3762 . C <*> 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 X 3763 . C <*> 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 X 3764 . A <*> 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 X 3765 . C <*> 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 X 3766 . A <*> 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 X 3767 . A <*> 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 X 3768 . A <*> 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 X 3769 . T <*> 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 X 3770 . C <*> 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 X 3771 . T <*> 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 X 3772 . A <*> 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 X 3773 . C <*> 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 X 3774 . T <*> 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 X 3775 . C <*> 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 X 3776 . T <*> 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 X 3777 . C <*> 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 X 3778 . T <*> 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 X 3779 . G <*> 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 X 3780 . C <*> 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 X 3781 . C <*> 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 X 3782 . T <*> 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 X 3783 . C <*> 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 X 3784 . T <*> 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 X 3785 . G <*> 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 X 3786 . T <*> 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 X 3787 . G <*> 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 X 3788 . G <*> 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 X 3789 . G <*> 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 X 3790 . T <*> 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 X 3791 . T <*> 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 X 3792 . G A,<*> 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 X 3793 . A <*> 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 X 3794 . C <*> 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 X 3795 . C <*> 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 X 3796 . T <*> 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 X 3797 . A <*> 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 X 3798 . T <*> 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 X 3799 . T <*> 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 X 3800 . C <*> 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 X 3801 . T <*> 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 X 3802 . G <*> 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 X 3803 . G <*> 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 X 3804 . A <*> 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 X 3805 . C <*> 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 X 3806 . A <*> 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 X 3807 . C <*> 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 X 3808 . G <*> 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 X 3809 . T <*> 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 X 3810 . C <*> 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 X 3811 . A C,<*> 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 X 3812 . T <*> 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 X 3813 . A <*> 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 X 3814 . G <*> 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 X 3815 . A <*> 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 X 3816 . A <*> 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 X 3817 . A <*> 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 X 3818 . T <*> 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 X 3819 . A <*> 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 X 3820 . G <*> 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 X 3821 . A <*> 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 X 3822 . G <*> 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 X 3823 . T <*> 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 X 3824 . C <*> 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 X 3825 . C <*> 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 X 3826 . T <*> 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 X 3827 . G <*> 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 X 3828 . C <*> 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 X 3829 . A <*> 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 X 3830 . A <*> 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 X 3831 . C A,<*> 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 X 3832 . A <*> 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 X 3833 . C <*> 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 X 3834 . G <*> 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 X 3835 . T <*> 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 X 3836 . G C,<*> 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 X 3837 . G <*> 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 X 3838 . C <*> 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 X 3839 . C <*> 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 X 3840 . G <*> 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 X 3841 . T <*> 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 X 3842 . C <*> 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 X 3843 . T <*> 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 X 3844 . G <*> 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 X 3845 . T <*> 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 X 3846 . G <*> 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 X 3847 . T <*> 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 X 3848 . C <*> 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 X 3849 . T <*> 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 X 3850 . G <*> 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 X 3851 . G <*> 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 X 3852 . C <*> 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 X 3853 . T <*> 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 X 3854 . T <*> 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 X 3855 . C <*> 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 X 3856 . T <*> 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 X 3857 . C <*> 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 X 3858 . T <*> 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 X 3859 . C <*> 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 X 3860 . G <*> 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 X 3861 . C <*> 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 X 3862 . T <*> 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 X 3863 . T <*> 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 X 3864 . A <*> 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 X 3865 . G <*> 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 X 3866 . C <*> 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 X 3867 . A <*> 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 X 3868 . T <*> 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 X 3869 . C <*> 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 X 3870 . T <*> 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 X 3871 . T <*> 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 X 3872 . G <*> 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 X 3873 . T <*> 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 X 3874 . T <*> 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 X 3875 . T <*> 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 X 3876 . C <*> 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 X 3877 . C <*> 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 X 3878 . A <*> 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 X 3879 . A <*> 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 X 3880 . G <*> 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 X 3881 . G <*> 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 X 3882 . T <*> 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 X 3883 . C <*> 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 X 3884 . C <*> 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 X 3885 . T <*> 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 X 3886 . C <*> 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 X 3887 . C <*> 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 X 3888 . C <*> 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 X 3889 . A <*> 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 X 3890 . C <*> 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 X 3891 . A <*> 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 X 3892 . G <*> 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 X 3893 . T <*> 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 X 3894 . G <*> 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 X 3895 . T <*> 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 X 3896 . A <*> 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 X 3897 . G <*> 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 X 3898 . C <*> 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 X 3899 . A <*> 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 X 3900 . T <*> 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 X 3901 . G <*> 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 X 3902 . C <*> 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 X 3903 . A <*> 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 X 3904 . C <*> 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 X 3905 . C <*> 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 X 3906 . T <*> 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 X 3907 . G <*> 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 X 3908 . C <*> 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 X 3909 . T <*> 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 X 3910 . A <*> 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 X 3911 . C <*> 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 X 3912 . A C,<*> 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 X 3913 . C <*> 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 X 3914 . T <*> 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 X 3915 . C <*> 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 X 3916 . C <*> 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 X 3917 . T <*> 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 X 3918 . T <*> 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 X 3919 . C <*> 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 X 3920 . T <*> 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 X 3921 . T <*> 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 X 3922 . A <*> 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 X 3923 . G <*> 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 X 3924 . G <*> 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 X 3925 . G <*> 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 X 3926 . C <*> 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 X 3927 . T <*> 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 X 3928 . G <*> 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 X 3929 . A <*> 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 X 3930 . T <*> 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 X 3931 . A <*> 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 X 3932 . T <*> 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 X 3933 . T <*> 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 X 3934 . C <*> 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 X 3935 . C <*> 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 X 3936 . A G,<*> 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 X 3937 . C <*> 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 X 3938 . G <*> 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 X 3939 . C <*> 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 X 3940 . A <*> 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 X 3941 . C <*> 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 X 3942 . C <*> 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 X 3943 . T <*> 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 X 3944 . G <*> 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 X 3945 . C <*> 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 X 3946 . T <*> 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 X 3947 . A <*> 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 X 3948 . C <*> 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 X 3949 . A C,<*> 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 X 3950 . C <*> 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 X 3951 . T <*> 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 X 3952 . C <*> 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 X 3953 . C <*> 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 X 3954 . T <*> 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 X 3955 . T <*> 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 X 3956 . C <*> 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 X 3957 . T <*> 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 X 3958 . T <*> 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 X 3959 . A <*> 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 X 3960 . T <*> 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 X 3961 . G <*> 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 X 3962 . G <*> 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 X 3963 . C <*> 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 X 3964 . T <*> 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 X 3965 . G <*> 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 X 3966 . A <*> 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 X 3967 . T <*> 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 X 3968 . A <*> 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 X 3969 . T <*> 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 X 3970 . T <*> 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 X 3971 . C <*> 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 X 3972 . C <*> 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 X 3973 . A <*> 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 X 3974 . C <*> 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 X 3975 . G <*> 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 X 3976 . C <*> 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 X 3977 . A <*> 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 X 3978 . C <*> 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 X 3979 . C <*> 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 X 3980 . T <*> 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 X 3981 . G <*> 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 X 3982 . C <*> 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 X 3983 . T <*> 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 X 3984 . A <*> 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 X 3985 . C <*> 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 X 3986 . A <*> 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 X 3987 . C <*> 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 X 3988 . T <*> 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 X 3989 . C <*> 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 X 3990 . C <*> 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 X 3991 . T <*> 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 X 3992 . T <*> 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 X 3993 . C <*> 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 X 3994 . T <*> 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 X 3995 . T <*> 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 X 3996 . A <*> 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 X 3997 . G C,<*> 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 X 3998 . G <*> 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 X 3999 . G A,<*> 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 X 4000 . C <*> 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 X 4001 . T <*> 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 X 4002 . G <*> 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 X 4003 . A <*> 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 X 4004 . T <*> 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 X 4005 . A <*> 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 X 4006 . T <*> 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 X 4007 . T G,<*> 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 X 4008 . C <*> 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 X 4009 . C <*> 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 X 4010 . A <*> 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 X 4011 . C <*> 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 X 4012 . A <*> 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 X 4013 . C <*> 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 X 4014 . A <*> 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 X 4015 . C <*> 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 X 4016 . C <*> 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 X 4017 . C <*> 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 X 4018 . G <*> 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 X 4019 . C <*> 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 X 4020 . T <*> 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 X 4021 . A <*> 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 X 4022 . C <*> 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 X 4023 . A <*> 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 X 4024 . C <*> 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 X 4025 . T <*> 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 X 4026 . C <*> 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 X 4027 . C <*> 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 X 4028 . T <*> 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 X 4029 . T <*> 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 X 4030 . C <*> 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 X 4031 . T <*> 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 X 4032 . T <*> 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 X 4033 . A <*> 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 X 4034 . G <*> 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 X 4035 . G T,<*> 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 X 4036 . G <*> 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 X 4037 . C <*> 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 X 4038 . T <*> 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 X 4039 . G <*> 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 X 4040 . A <*> 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 X 4041 . T <*> 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 X 4042 . A <*> 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 X 4043 . T <*> 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 X 4044 . T <*> 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 X 4045 . C <*> 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 X 4046 . C <*> 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 X 4047 . A <*> 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 X 4048 . C <*> 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 X 4049 . G <*> 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 X 4050 . C <*> 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 X 4051 . A <*> 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 X 4052 . C <*> 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 X 4053 . C <*> 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 X 4054 . C <*> 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 X 4055 . G <*> 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 X 4056 . C <*> 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 X 4057 . T <*> 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 X 4058 . A <*> 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 X 4059 . C <*> 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 X 4060 . A <*> 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 X 4061 . C <*> 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 X 4062 . T <*> 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 X 4063 . C <*> 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 X 4064 . C <*> 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 X 4065 . T <*> 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 X 4066 . T <*> 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 X 4067 . C <*> 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 X 4068 . T <*> 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 X 4069 . T <*> 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 X 4070 . A <*> 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 X 4071 . G <*> 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 X 4072 . G <*> 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 X 4073 . G <*> 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 X 4074 . C <*> 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 X 4075 . T <*> 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 X 4076 . G <*> 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 X 4077 . A <*> 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 X 4078 . T <*> 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 X 4079 . A <*> 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 X 4080 . T <*> 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 X 4081 . T <*> 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 X 4082 . C <*> 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 X 4083 . C <*> 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 X 4084 . A <*> 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 X 4085 . C <*> 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 X 4086 . G <*> 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 X 4087 . C <*> 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 X 4088 . A <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 X 4089 . C <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 X 4090 . C <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 X 4091 . T <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 X 4092 . G <*> 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 X 4093 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 X 4094 . T <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 X 4095 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 X 4096 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 X 4097 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 X 4098 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 X 4099 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 X 4100 . C <*> 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 X 4101 . C <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 bcftools-1.21/test/mpileup.c.1.out000066400000000000000000000126721467060157400170350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 302 . T TA 999 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AF1=0.685575;AC1=4;DP4=2,4,8,11;MQ=51;FQ=61.4911;PV4=1,1,1,1 GT:PL:DP:DV 0/1:167,0,96:11:6 0/1:157,0,9:7:6 1/1:201,21,0:7:7 17 828 . T C 999 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AF1=0.656389;AC1=4;DP4=2,4,8,11;MQ=60;FQ=89.3748;PV4=1,1,1,0.32233 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 17 834 . G A 999 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AF1=0.646503;AC1=4;DP4=2,3,7,10;MQ=60;FQ=68.6952;PV4=1,1,1,0.228905 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 17 1665 . T C 3.14059 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AF1=0.167199;AC1=1;DP4=7,11,1,1;MQ=56;FQ=3.56819;PV4=1,0.239991,0.0798553,0.27333 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 17 1869 . A T 134.348 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AF1=0.598209;AC1=4;DP4=6,9,5,4;MQ=59;FQ=138.299;PV4=0.675175,0.0234896,1,0.324361 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 17 2041 . G A 999 . 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DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AF1=0.665739;AC1=4;DP4=4,7,10,6;MQ=60;FQ=358.057;PV4=0.25186,0.0986321,1,1 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 17 3936 . A G 999 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AF1=0.666004;AC1=4;DP4=5,6,6,17;MQ=57;FQ=999;PV4=0.434446,0.125787,1,1 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.c.X.2.out000066400000000000000000000126021467060157400172350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 X 302 . T TA 999 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AF1=0.685575;AC1=4;DP4=2,4,8,11;MQ=51;FQ=61.4911;PV4=1,1,1,1 GT:PL:DP:DV 0/1:167,0,96:11:6 0:157,0,9:7:6 1/1:201,21,0:7:7 X 828 . T C 999 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AF1=0.656389;AC1=4;DP4=2,4,8,11;MQ=60;FQ=89.3748;PV4=1,1,1,0.32233 GT:PL:DP:DV 0/1:211,0,35:12:10 0:116,91:9:5 1/1:120,12,0:4:4 X 834 . G A 999 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AF1=0.646503;AC1=4;DP4=2,3,7,10;MQ=60;FQ=68.6952;PV4=1,1,1,0.228905 GT:PL:DP:DV 0/1:185,0,46:11:9 0:128,59:8:5 1/1:89,9,0:3:3 X 1665 . T C 3.14059 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AF1=0.167199;AC1=1;DP4=7,11,1,1;MQ=56;FQ=3.56819;PV4=1,0.239991,0.0798553,0.27333 GT:PL:DP:DV 0/0:0,21,185:7:0 0:0,222:9:0 0/1:35,0,51:4:2 X 1869 . A T 134.348 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AF1=0.598209;AC1=4;DP4=6,9,5,4;MQ=59;FQ=138.299;PV4=0.675175,0.0234896,1,0.324361 GT:PL:DP:DV 0/1:115,0,224:18:7 0:16,104:5:1 1/1:42,3,0:1:1 X 2041 . G A 999 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AF1=0.665982;AC1=4;DP4=6,5,12,7;MQ=59;FQ=999;PV4=0.71163,1,0.228209,0.143795 GT:PL:DP:DV 0/1:229,0,212:21:11 0:32,24:2:1 1/1:223,21,0:7:7 X 2220 . G A 999 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AF1=0.656341;AC1=4;DP4=6,2,1,11;MQ=59;FQ=139.373;PV4=0.00443756,1,1,1 GT:PL:DP:DV 0/1:139,0,130:12:6 0:69,46:4:2 1/1:131,12,0:4:4 X 2564 . A G 227.769 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AF1=0.656337;AC1=4;DP4=1,4,4,5;MQ=60;FQ=97.3723;PV4=0.58042,1,1,1 GT:PL:DP:DV 0/1:88,0,78:6:3 0:57,56:4:2 1/1:124,12,0:4:4 X 3104 . C T 24.364 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AF1=0.170892;AC1=1;DP4=8,15,2,0;MQ=59;FQ=25.179;PV4=0.15,1,1,1 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 X 3587 . G A 353.302 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AF1=0.665739;AC1=4;DP4=4,7,10,6;MQ=60;FQ=358.057;PV4=0.25186,0.0986321,1,1 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 X 3936 . A G 999 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AF1=0.666004;AC1=4;DP4=5,6,6,17;MQ=57;FQ=999;PV4=0.434446,0.125787,1,1 GT:PL:DP:DV 0/1:233,0,206:20:11 0:77,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.c.X.out000066400000000000000000000126271467060157400171040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 X 302 . T TA 999 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AF1=0.685575;AC1=4;DP4=2,4,8,11;MQ=51;FQ=61.4911;PV4=1,1,1,1 GT:PL:DP:DV 0/1:167,0,96:11:6 0:157,0,9:7:6 1/1:201,21,0:7:7 X 828 . T C 999 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AF1=0.656389;AC1=4;DP4=2,4,8,11;MQ=60;FQ=89.3748;PV4=1,1,1,0.32233 GT:PL:DP:DV 0/1:211,0,35:12:10 0:116,91:9:5 1/1:120,12,0:4:4 X 834 . G A 999 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AF1=0.646503;AC1=4;DP4=2,3,7,10;MQ=60;FQ=68.6952;PV4=1,1,1,0.228905 GT:PL:DP:DV 0/1:185,0,46:11:9 0:128,59:8:5 1/1:89,9,0:3:3 X 1665 . T C 3.14059 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AF1=0.167199;AC1=1;DP4=7,11,1,1;MQ=56;FQ=3.56819;PV4=1,0.239991,0.0798553,0.27333 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 X 1869 . A T 134.348 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AF1=0.598209;AC1=4;DP4=6,9,5,4;MQ=59;FQ=138.299;PV4=0.675175,0.0234896,1,0.324361 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 X 2041 . G A 999 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AF1=0.665982;AC1=4;DP4=6,5,12,7;MQ=59;FQ=999;PV4=0.71163,1,0.228209,0.143795 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 X 2220 . G A 999 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AF1=0.656341;AC1=4;DP4=6,2,1,11;MQ=59;FQ=139.373;PV4=0.00443756,1,1,1 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 X 2564 . A G 227.769 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AF1=0.656337;AC1=4;DP4=1,4,4,5;MQ=60;FQ=97.3723;PV4=0.58042,1,1,1 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 X 3104 . C T 24.364 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AF1=0.170892;AC1=1;DP4=8,15,2,0;MQ=59;FQ=25.179;PV4=0.15,1,1,1 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 X 3587 . G A 353.302 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AF1=0.665739;AC1=4;DP4=4,7,10,6;MQ=60;FQ=358.057;PV4=0.25186,0.0986321,1,1 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 X 3936 . A G 999 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AF1=0.666004;AC1=4;DP4=5,6,6,17;MQ=57;FQ=999;PV4=0.434446,0.125787,1,1 GT:PL:DP:DV 0/1:233,0,206:20:11 0:77,58:6:4 1/1:196,24,0:8:8 bcftools-1.21/test/mpileup.c.X.vcf000066400000000000000000023504331467060157400170550ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 X 1 . A <*> 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 2 . A <*> 0 . DP=11;I16=11,0,0,0,439,17587,0,0,319,9251,0,0,226,5030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 3 . G <*> 0 . DP=11;I16=11,0,0,0,431,16971,0,0,319,9251,0,0,229,5111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 4 . C <*> 0 . DP=11;I16=11,0,0,0,423,16417,0,0,319,9251,0,0,232,5202,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,71:3:0 X 5 . T <*> 0 . DP=11;I16=11,0,0,0,450,18520,0,0,319,9251,0,0,234,5252,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 6 . T <*> 0 . DP=11;I16=11,0,0,0,403,14847,0,0,319,9251,0,0,236,5310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 7 . C <*> 0 . DP=11;I16=11,0,0,0,446,18114,0,0,319,9251,0,0,237,5327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 8 . T <*> 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 9 . C <*> 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 10 . A <*> 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 X 11 . C <*> 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 12 . C <*> 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 13 . C <*> 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 14 . T <*> 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 15 . G <*> 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 16 . T <*> 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 17 . T <*> 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 X 18 . C <*> 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 X 19 . C <*> 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 X 20 . T <*> 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 X 21 . G <*> 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 X 22 . C <*> 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 X 23 . A <*> 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 X 24 . T <*> 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 X 25 . A <*> 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 X 26 . G <*> 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 X 27 . A <*> 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 X 28 . T <*> 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 X 29 . A <*> 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 X 30 . A <*> 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 X 31 . T <*> 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 X 32 . T <*> 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 X 33 . G <*> 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 X 34 . C <*> 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 X 35 . A <*> 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 X 36 . T <*> 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 X 37 . G <*> 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 X 38 . A <*> 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 X 39 . C <*> 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 X 40 . A <*> 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 X 41 . A <*> 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 X 42 . T <*> 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 X 43 . T <*> 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 X 44 . G <*> 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 X 45 . C <*> 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 X 46 . C <*> 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 X 47 . T <*> 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 X 48 . T <*> 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 X 49 . G <*> 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 X 50 . T <*> 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 X 51 . C <*> 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 X 52 . C <*> 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 X 53 . C <*> 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 X 54 . T <*> 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 X 55 . G <*> 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 X 56 . C <*> 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 X 57 . T <*> 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 X 58 . G <*> 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 X 59 . A <*> 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 X 60 . A <*> 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 X 61 . T <*> 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 X 62 . G <*> 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 X 63 . T <*> 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 X 64 . G <*> 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 X 65 . C <*> 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 X 66 . T <*> 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 X 67 . C <*> 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 X 68 . T <*> 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 X 69 . G <*> 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 X 70 . G <*> 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 X 71 . G <*> 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 X 72 . G <*> 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 X 73 . T <*> 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 X 74 . C <*> 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 X 75 . T <*> 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 X 76 . C <*> 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 X 77 . T <*> 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 X 78 . G <*> 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 X 79 . G <*> 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 X 80 . G <*> 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 X 81 . G <*> 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 X 82 . T <*> 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 X 83 . C <*> 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 X 84 . T <*> 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 X 85 . C <*> 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 X 86 . A <*> 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 X 87 . C <*> 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 X 88 . C <*> 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 X 89 . C <*> 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 X 90 . A <*> 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 X 91 . C <*> 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 X 92 . G <*> 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 X 93 . A <*> 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 X 94 . C <*> 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 X 95 . C <*> 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 X 96 . A <*> 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 X 97 . A <*> 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 X 98 . C <*> 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 X 99 . T <*> 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 X 100 . C <*> 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 X 101 . C <*> 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 X 102 . C <*> 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 X 103 . T <*> 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 X 104 . G <*> 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 X 105 . G <*> 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 X 106 . G <*> 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 X 107 . C <*> 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 X 108 . C <*> 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 X 109 . T <*> 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 X 110 . G <*> 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 X 111 . G <*> 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 X 112 . C <*> 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 X 113 . A <*> 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 X 114 . C <*> 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 X 115 . C <*> 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 X 116 . A <*> 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 X 117 . G <*> 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 X 118 . G <*> 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 X 119 . G <*> 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 X 120 . A <*> 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 X 121 . G <*> 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 X 122 . C <*> 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 X 123 . T <*> 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 X 124 . T <*> 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 X 125 . A <*> 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 X 126 . A <*> 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 X 127 . C <*> 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 X 128 . A <*> 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 X 129 . A <*> 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 X 130 . A <*> 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 X 131 . C <*> 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 X 132 . A <*> 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 X 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 X 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 X 135 . T <*> 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 X 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 X 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 X 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 X 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 X 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 X 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 X 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 X 143 . G <*> 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 X 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 X 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 X 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 X 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 X 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 X 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 X 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 X 151 . G <*> 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 X 152 . C <*> 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 X 153 . A <*> 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 X 154 . T <*> 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 X 155 . C <*> 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 X 156 . C <*> 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 X 157 . C <*> 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 X 158 . T <*> 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 X 159 . A <*> 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 X 160 . G <*> 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 X 161 . A <*> 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 X 162 . A <*> 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 X 163 . G <*> 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 X 164 . T <*> 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 X 165 . G <*> 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 X 166 . A <*> 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 X 167 . A <*> 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 X 168 . G <*> 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 X 169 . C <*> 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 X 170 . C <*> 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 X 171 . A <*> 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 X 172 . C <*> 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 X 173 . C <*> 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 X 174 . G <*> 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 X 175 . C <*> 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 X 176 . C <*> 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 X 177 . C <*> 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 X 178 . A <*> 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 X 179 . A <*> 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 X 180 . A <*> 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 X 181 . G <*> 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 X 182 . A <*> 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 X 183 . C <*> 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 X 184 . A <*> 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 X 185 . C <*> 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 X 186 . G <*> 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 X 187 . C <*> 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 X 188 . C <*> 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 X 189 . C <*> 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 X 190 . A <*> 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 X 191 . T <*> 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 X 192 . G <*> 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 X 193 . T <*> 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 X 194 . C <*> 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 X 195 . C <*> 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 X 196 . A <*> 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 X 197 . G <*> 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 X 198 . C <*> 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 X 199 . T <*> 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 X 200 . T <*> 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 X 201 . A <*> 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 X 202 . A <*> 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 X 203 . C <*> 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 X 204 . C <*> 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 X 205 . T <*> 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 X 206 . G <*> 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 X 207 . C <*> 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 X 208 . A <*> 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 X 209 . T <*> 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 X 210 . C <*> 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 X 211 . C <*> 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 X 212 . C <*> 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 X 213 . T <*> 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 X 214 . A <*> 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 X 215 . G <*> 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 X 216 . A <*> 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 X 217 . A <*> 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 X 218 . G <*> 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 X 219 . T <*> 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 X 220 . G <*> 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 X 221 . A <*> 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 X 222 . A <*> 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 X 223 . G <*> 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 X 224 . G <*> 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 X 225 . C <*> 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 X 226 . A <*> 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 X 227 . C <*> 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 X 228 . C <*> 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 X 229 . G <*> 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 X 230 . C <*> 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 X 231 . C <*> 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 X 232 . C <*> 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 X 233 . A <*> 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 X 234 . A <*> 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 X 235 . A <*> 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 X 236 . G <*> 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 X 237 . A <*> 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 X 238 . C <*> 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 X 239 . A <*> 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 X 240 . C <*> 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 X 241 . G <*> 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 X 242 . C <*> 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 X 243 . C <*> 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 X 244 . C <*> 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 X 245 . A <*> 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 X 246 . T <*> 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 X 247 . G <*> 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 X 248 . T <*> 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 X 249 . C <*> 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 X 250 . C <*> 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 X 251 . A <*> 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 X 252 . G <*> 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 X 253 . C <*> 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 X 254 . T <*> 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 X 255 . T <*> 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 X 256 . A <*> 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 X 257 . T <*> 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 X 258 . T <*> 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 X 259 . C <*> 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 X 260 . T <*> 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 X 261 . G <*> 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 X 262 . C <*> 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 X 263 . C <*> 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 X 264 . C <*> 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 X 265 . A <*> 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 X 266 . G <*> 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 X 267 . T <*> 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 X 268 . T <*> 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 X 269 . C <*> 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 X 270 . C <*> 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 X 271 . T <*> 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 X 272 . C <*> 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 X 273 . T <*> 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 X 274 . C <*> 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 X 275 . C <*> 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 X 276 . A <*> 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 X 277 . G <*> 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 X 278 . A <*> 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 X 279 . A <*> 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 X 280 . A <*> 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 X 281 . G <*> 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 X 282 . G <*> 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 X 283 . C <*> 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 X 284 . T <*> 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 X 285 . G <*> 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 X 286 . C <*> 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 X 287 . A <*> 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 X 288 . T <*> 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 X 289 . G <*> 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 X 290 . G <*> 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 X 291 . T <*> 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 X 292 . T <*> 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 X 293 . G <*> 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 X 294 . A <*> 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 X 295 . C <*> 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 X 296 . A <*> 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 X 297 . C <*> 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 X 298 . A <*> 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 X 299 . C <*> 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 X 300 . A <*> 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 X 301 . G <*> 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 X 302 . T <*> 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 X 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 X 303 . G <*> 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 X 304 . C <*> 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 X 305 . C <*> 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 X 306 . T <*> 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 X 307 . G <*> 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 X 308 . C <*> 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 X 309 . G <*> 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 X 310 . A <*> 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 X 311 . C <*> 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 X 312 . A <*> 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 X 313 . A <*> 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 X 314 . A <*> 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 X 315 . G <*> 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 X 316 . C <*> 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 X 317 . T <*> 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 X 318 . G <*> 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 X 319 . A <*> 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 X 320 . A <*> 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 X 321 . T <*> 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 X 322 . G <*> 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 X 323 . C <*> 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 X 324 . T <*> 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 X 325 . A <*> 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 X 326 . T <*> 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 X 327 . C <*> 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 X 328 . A <*> 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 X 329 . T <*> 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 X 330 . T <*> 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 X 331 . T <*> 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 X 332 . A <*> 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 X 333 . A <*> 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 X 334 . A <*> 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 X 335 . A <*> 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 X 336 . A <*> 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 X 337 . C <*> 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 X 338 . T <*> 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 X 339 . C <*> 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 X 340 . C <*> 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 X 341 . T <*> 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 X 342 . T <*> 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 X 343 . G <*> 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 X 344 . C <*> 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 X 345 . T <*> 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 X 346 . G <*> 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 X 347 . G <*> 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 X 348 . T <*> 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 X 349 . T <*> 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 X 350 . T <*> 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 X 351 . G <*> 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 X 352 . A <*> 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 X 353 . G <*> 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 X 354 . A <*> 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 X 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 X 356 . G <*> 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 X 357 . C <*> 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 X 358 . A <*> 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 X 359 . G <*> 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 X 360 . A <*> 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 X 361 . A <*> 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 X 362 . A <*> 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 X 363 . A <*> 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 X 364 . T <*> 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 X 365 . G <*> 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 X 366 . A <*> 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 X 367 . T <*> 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 X 368 . A <*> 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 X 369 . T <*> 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 X 370 . C <*> 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 X 371 . T <*> 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 X 372 . C <*> 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 X 373 . A <*> 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 X 374 . T <*> 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 X 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 X 376 . G <*> 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 X 377 . T <*> 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 X 378 . T <*> 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 X 379 . G <*> 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 X 380 . C <*> 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 X 381 . T <*> 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 X 382 . T <*> 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 X 383 . T <*> 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 X 384 . A <*> 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 X 385 . C <*> 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 X 386 . T <*> 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 X 387 . T <*> 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 X 388 . T <*> 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 X 389 . G <*> 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 X 390 . C <*> 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 X 391 . A <*> 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 X 392 . T <*> 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 X 393 . A <*> 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 X 394 . T <*> 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 X 395 . T <*> 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 X 396 . T <*> 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 X 397 . T <*> 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 X 398 . A <*> 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 X 399 . A <*> 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 X 400 . A <*> 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 X 401 . A <*> 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 X 402 . T <*> 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 X 403 . T <*> 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 X 404 . G <*> 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 X 405 . T <*> 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 X 406 . G <*> 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 X 407 . A <*> 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 X 408 . C <*> 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 X 409 . T <*> 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 X 410 . T <*> 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 X 411 . T <*> 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 X 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 X 413 . A <*> 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 X 414 . T <*> 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 X 415 . G <*> 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 X 416 . G <*> 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 X 417 . C <*> 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 X 418 . A <*> 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 X 419 . T <*> 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 X 420 . A <*> 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 X 421 . A <*> 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 X 422 . A <*> 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 X 423 . T <*> 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 X 424 . A <*> 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 X 425 . A <*> 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 X 426 . T <*> 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 X 427 . A <*> 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 X 428 . C <*> 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 X 429 . T <*> 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 X 430 . G <*> 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 X 431 . G <*> 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 X 432 . T <*> 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 X 433 . T <*> 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 X 434 . T <*> 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 X 435 . A <*> 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 X 436 . T <*> 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 X 437 . T <*> 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 X 438 . A <*> 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 X 439 . C <*> 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 X 440 . A <*> 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 X 441 . G <*> 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 X 442 . A <*> 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 X 443 . A <*> 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 X 444 . G <*> 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 X 445 . C <*> 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 X 446 . A <*> 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 X 447 . C <*> 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 X 448 . T <*> 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 X 449 . A <*> 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 X 450 . G <*> 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 X 451 . A <*> 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 X 452 . A <*> 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 X 453 . A <*> 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 X 454 . A <*> 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 X 455 . T <*> 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 X 456 . G <*> 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 X 457 . C <*> 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 X 458 . A <*> 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 X 459 . T <*> 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 X 460 . G <*> 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 X 461 . T <*> 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 X 462 . G <*> 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 X 463 . G <*> 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 X 464 . A <*> 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 X 465 . C <*> 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 X 466 . A <*> 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 X 467 . A <*> 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 X 468 . A <*> 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 X 469 . A <*> 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 X 470 . G <*> 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 X 471 . T <*> 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 X 472 . T <*> 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 X 473 . G <*> 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 X 474 . G <*> 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 X 475 . G <*> 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 X 476 . A <*> 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 X 477 . T <*> 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 X 478 . T <*> 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 X 479 . A <*> 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 X 480 . G <*> 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 X 481 . G <*> 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 X 482 . A <*> 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 X 483 . G <*> 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 X 484 . A <*> 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 X 485 . G <*> 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 X 486 . A <*> 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 X 487 . G <*> 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 X 488 . A <*> 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 X 489 . A <*> 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 X 490 . A <*> 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 X 491 . T <*> 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 X 492 . G <*> 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 X 493 . A <*> 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 X 494 . A <*> 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 X 495 . G <*> 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 X 496 . A <*> 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 X 497 . C <*> 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 X 498 . A <*> 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 X 499 . T <*> 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 X 500 . A <*> 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 X 501 . T <*> 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 X 502 . G <*> 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 X 503 . T <*> 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 X 504 . C <*> 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 X 505 . C <*> 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 X 506 . A <*> 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 X 507 . C <*> 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 X 508 . A <*> 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 X 509 . C <*> 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 X 510 . A <*> 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 X 511 . A <*> 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 X 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 X 513 . A <*> 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 X 514 . A T,<*> 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 X 515 . C <*> 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 X 516 . C <*> 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 X 517 . T <*> 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 X 518 . G <*> 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 X 519 . T <*> 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 X 520 . T <*> 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 X 521 . C <*> 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 X 522 . A <*> 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 X 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 X 524 . T <*> 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 X 525 . G <*> 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 X 526 . C <*> 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 X 527 . A <*> 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 X 528 . G <*> 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 X 529 . C <*> 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 X 530 . T <*> 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 X 531 . T <*> 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 X 532 . T <*> 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 X 533 . C <*> 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 X 534 . T <*> 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 X 535 . A <*> 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 X 536 . C <*> 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 X 537 . C <*> 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 X 538 . A <*> 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 X 539 . T <*> 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 X 540 . C <*> 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 X 541 . A <*> 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 X 542 . C <*> 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 X 543 . C <*> 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 X 544 . A <*> 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 X 545 . A <*> 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 X 546 . A <*> 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 X 547 . A <*> 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 X 548 . A <*> 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 X 549 . T G,<*> 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 X 550 . T <*> 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 X 551 . G <*> 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 X 552 . C <*> 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 X 553 . A <*> 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 X 554 . A <*> 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 X 555 . A <*> 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 X 556 . C <*> 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 X 557 . A <*> 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 X 558 . A <*> 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 X 559 . C A,<*> 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 X 560 . C <*> 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 X 561 . A <*> 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 X 562 . C <*> 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 X 563 . A <*> 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 X 564 . C <*> 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 X 565 . G <*> 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 X 566 . C <*> 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 X 567 . C <*> 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 X 568 . C <*> 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 X 569 . T <*> 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 X 570 . T <*> 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 X 571 . C <*> 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 X 572 . A <*> 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 X 573 . A <*> 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 X 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 X 575 . T <*> 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 X 576 . G <*> 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 X 577 . G <*> 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 X 578 . G <*> 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 X 579 . G <*> 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 X 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 X 581 . A <*> 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 X 582 . C <*> 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 X 583 . T <*> 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 X 584 . C <*> 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 X 585 . A <*> 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 X 586 . T <*> 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 X 587 . C <*> 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 X 588 . A <*> 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 X 589 . A <*> 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 X 590 . C <*> 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 X 591 . A <*> 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 X 592 . A <*> 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 X 593 . C <*> 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 X 594 . A <*> 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 X 595 . A <*> 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 X 596 . A <*> 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 X 597 . C <*> 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 X 598 . T <*> 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 X 599 . T <*> 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 X 600 . G <*> 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 X 601 . T <*> 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 X 602 . G <*> 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 X 603 . G <*> 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 X 604 . T <*> 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 X 605 . T <*> 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 X 606 . T <*> 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 X 607 . A <*> 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 X 608 . C <*> 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 X 609 . C <*> 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 X 610 . C <*> 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 X 611 . A <*> 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 X 612 . C <*> 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 X 613 . A <*> 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 X 614 . C <*> 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 X 615 . A <*> 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 X 616 . A <*> 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 X 617 . T <*> 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 X 618 . G <*> 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 X 619 . G <*> 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 X 620 . A <*> 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 X 621 . A <*> 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 X 622 . G <*> 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 X 623 . A T,<*> 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 X 624 . C <*> 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 X 625 . C <*> 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 X 626 . A <*> 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 X 627 . C <*> 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 X 628 . T <*> 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 X 629 . T <*> 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 X 630 . A <*> 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 X 631 . G <*> 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 X 632 . C <*> 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 X 633 . A <*> 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 X 634 . A <*> 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 X 635 . C <*> 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 X 636 . A <*> 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 X 637 . A <*> 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 X 638 . A <*> 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 X 639 . A <*> 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 X 640 . A <*> 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 X 641 . G <*> 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 X 642 . G <*> 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 X 643 . A <*> 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 X 644 . C A,<*> 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 X 645 . C <*> 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 X 646 . A T,<*> 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 X 647 . A <*> 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 X 648 . A <*> 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 X 649 . C <*> 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 X 650 . T <*> 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 X 651 . C <*> 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 X 652 . C <*> 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 X 653 . T <*> 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 X 654 . G <*> 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 X 655 . G <*> 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 X 656 . T <*> 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 X 657 . A <*> 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 X 658 . C <*> 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 X 659 . A <*> 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 X 660 . T <*> 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 X 661 . G <*> 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 X 662 . C <*> 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 X 663 . A <*> 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 X 664 . A <*> 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 X 665 . C <*> 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 X 666 . T <*> 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 X 667 . G <*> 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 X 668 . A <*> 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 X 669 . C <*> 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 X 670 . A <*> 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 X 671 . G <*> 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 X 672 . A <*> 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 X 673 . T <*> 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 X 674 . G <*> 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 X 675 . A <*> 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 X 676 . A <*> 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 X 677 . T <*> 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 X 678 . C <*> 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 X 679 . T <*> 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 X 680 . C <*> 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 X 681 . A <*> 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 X 682 . A <*> 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 X 683 . A <*> 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 X 684 . C <*> 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 X 685 . G <*> 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 X 686 . C <*> 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 X 687 . A <*> 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 X 688 . T <*> 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 X 689 . T A,<*> 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 X 690 . C <*> 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 X 691 . C <*> 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 X 692 . T <*> 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 X 693 . C <*> 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 X 694 . C <*> 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 X 695 . G <*> 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 X 696 . T <*> 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 X 697 . G <*> 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 X 698 . T <*> 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 X 699 . G <*> 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 X 700 . A <*> 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 X 701 . A <*> 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 X 702 . A <*> 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 X 703 . G <*> 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 X 704 . A T,<*> 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 X 705 . A <*> 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 X 706 . G <*> 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 X 707 . C <*> 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 X 708 . C <*> 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 X 709 . G <*> 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 X 710 . G <*> 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 X 711 . A <*> 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 X 712 . C <*> 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 X 713 . T <*> 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 X 714 . C <*> 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 X 715 . A <*> 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 X 716 . C <*> 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 X 717 . A <*> 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 X 718 . G <*> 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 X 719 . G <*> 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 X 720 . G <*> 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 X 721 . C <*> 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 X 722 . A <*> 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 X 723 . A <*> 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 X 724 . C <*> 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 X 725 . A <*> 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 X 726 . C <*> 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 X 727 . A C,<*> 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 X 728 . C <*> 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 X 729 . T <*> 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 X 730 . A <*> 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 X 731 . T <*> 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 X 732 . C <*> 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 X 733 . T <*> 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 X 734 . G <*> 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 X 735 . A <*> 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 X 736 . C <*> 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 X 737 . T <*> 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 X 738 . G <*> 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 X 739 . T <*> 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 X 740 . T <*> 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 X 741 . T <*> 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 X 742 . C <*> 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 X 743 . A <*> 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 X 744 . T <*> 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 X 745 . G <*> 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 X 746 . G <*> 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 X 747 . G <*> 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 X 748 . A <*> 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 X 749 . A <*> 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 X 750 . A <*> 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 X 751 . G <*> 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 X 752 . T <*> 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 X 753 . C <*> 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 X 754 . T <*> 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 X 755 . G <*> 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 X 756 . G <*> 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 X 757 . A <*> 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 X 758 . A <*> 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 X 759 . A <*> 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 X 760 . C <*> 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 X 761 . G <*> 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 X 762 . G <*> 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 X 763 . C A,<*> 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 X 764 . A <*> 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 X 765 . A <*> 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 X 766 . C <*> 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 X 767 . A <*> 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 X 768 . C <*> 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 X 769 . C <*> 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 X 770 . A <*> 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 X 771 . T <*> 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 X 772 . T <*> 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 X 773 . G <*> 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 X 774 . A <*> 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 X 775 . G <*> 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 X 776 . A <*> 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 X 777 . C <*> 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 X 778 . A <*> 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 X 779 . G <*> 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 X 780 . A <*> 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 X 781 . A <*> 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 X 782 . A <*> 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 X 783 . A <*> 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 X 784 . C <*> 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 X 785 . A <*> 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 X 786 . G <*> 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 X 787 . G <*> 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 X 788 . T <*> 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 X 789 . G <*> 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 X 790 . A <*> 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 X 791 . G <*> 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 X 792 . T <*> 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 X 793 . G <*> 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 X 794 . G <*> 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 X 795 . T <*> 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 X 796 . T <*> 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 X 797 . G <*> 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 X 798 . C <*> 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 X 799 . C <*> 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 X 800 . T <*> 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 X 801 . G <*> 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 X 802 . G <*> 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 X 803 . G <*> 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 X 804 . G <*> 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 X 805 . C <*> 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 X 806 . C <*> 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 X 807 . A <*> 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 X 808 . G <*> 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 X 809 . G <*> 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 X 810 . G C,<*> 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 X 811 . A <*> 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 X 812 . A <*> 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 X 813 . C <*> 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 X 814 . T <*> 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 X 815 . T <*> 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 X 816 . T <*> 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 X 817 . C <*> 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 X 818 . T <*> 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 X 819 . G <*> 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 X 820 . G <*> 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 X 821 . G <*> 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 X 822 . G <*> 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 X 823 . T <*> 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 X 824 . C <*> 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 X 825 . A <*> 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 X 826 . T <*> 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 X 827 . A <*> 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 X 828 . T C,<*> 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 X 829 . T <*> 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 X 830 . C <*> 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 X 831 . T <*> 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 X 832 . C <*> 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 X 833 . T <*> 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 X 834 . G A,<*> 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 X 835 . T <*> 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 X 836 . G <*> 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 X 837 . T <*> 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 X 838 . T <*> 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 X 839 . G <*> 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 X 840 . A <*> 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 X 841 . T <*> 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 X 842 . T <*> 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 X 843 . C <*> 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 X 844 . T <*> 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 X 845 . G <*> 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 X 846 . G <*> 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 X 847 . T <*> 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 X 848 . G <*> 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 X 849 . G <*> 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 X 850 . T <*> 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 X 851 . G <*> 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 X 852 . G <*> 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 X 853 . A <*> 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 X 854 . A <*> 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 X 855 . A <*> 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 X 856 . C <*> 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 X 857 . A <*> 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 X 858 . A <*> 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 X 859 . G <*> 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 X 860 . A <*> 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 X 861 . C <*> 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 X 862 . T <*> 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 X 863 . G <*> 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 X 864 . T <*> 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 X 865 . C <*> 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 X 866 . C <*> 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 X 867 . C <*> 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 X 868 . A <*> 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 X 869 . G <*> 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 X 870 . C <*> 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 X 871 . C <*> 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 X 872 . T <*> 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 X 873 . G <*> 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 X 874 . G <*> 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 X 875 . G <*> 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 X 876 . T <*> 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 X 877 . G <*> 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 X 878 . A <*> 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 X 879 . T <*> 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 X 880 . A <*> 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 X 881 . C <*> 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 X 882 . A <*> 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 X 883 . G <*> 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 X 884 . C <*> 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 X 885 . G <*> 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 X 886 . A <*> 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 X 887 . G <*> 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 X 888 . A <*> 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 X 889 . C <*> 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 X 890 . C <*> 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 X 891 . C <*> 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 X 892 . C <*> 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 X 893 . A <*> 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 X 894 . T <*> 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 X 895 . C <*> 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 X 896 . T <*> 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 X 897 . C <*> 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 X 898 . T <*> 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 X 899 . A <*> 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 X 900 . C <*> 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 X 901 . C <*> 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 X 902 . A <*> 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 X 903 . A <*> 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 X 904 . A <*> 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 X 905 . A <*> 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 X 906 . A <*> 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 X 907 . A <*> 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 X 908 . T <*> 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 X 909 . T <*> 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 X 910 . A <*> 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 X 911 . A <*> 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 X 912 . A <*> 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 X 913 . A <*> 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 X 914 . A <*> 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 X 915 . T <*> 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 X 916 . T <*> 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 X 917 . A <*> 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 X 918 . G <*> 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 X 919 . C <*> 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 X 920 . T <*> 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 X 921 . G <*> 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 X 922 . G <*> 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 X 923 . G <*> 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 X 924 . C <*> 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 X 925 . A <*> 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 X 926 . T <*> 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 X 927 . G <*> 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 X 928 . G <*> 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 X 929 . T <*> 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 X 930 . G <*> 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 X 931 . G <*> 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 X 932 . T <*> 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 X 933 . G <*> 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 X 934 . C <*> 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 X 935 . A <*> 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 X 936 . T <*> 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 X 937 . G <*> 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 X 938 . C <*> 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 X 939 . C <*> 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 X 940 . T <*> 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 X 941 . G <*> 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 X 942 . T <*> 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 X 943 . A <*> 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 X 944 . G <*> 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 X 945 . T <*> 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 X 946 . C <*> 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 X 947 . C <*> 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 X 948 . C <*> 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 X 949 . A <*> 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 X 950 . G <*> 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 X 951 . C <*> 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 X 952 . T <*> 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 X 953 . A <*> 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 X 954 . T <*> 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 X 955 . T <*> 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 X 956 . C <*> 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 X 957 . A <*> 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 X 958 . C <*> 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 X 959 . A <*> 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 X 960 . G <*> 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 X 961 . T <*> 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 X 962 . G <*> 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 X 963 . C <*> 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 X 964 . T <*> 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 X 965 . G <*> 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 X 966 . A <*> 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 X 967 . G <*> 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 X 968 . G <*> 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 X 969 . T <*> 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 X 970 . G <*> 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 X 971 . G <*> 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 X 972 . G <*> 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 X 973 . A <*> 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 X 974 . A <*> 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 X 975 . G <*> 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 X 976 . A <*> 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 X 977 . T <*> 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 X 978 . G <*> 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 X 979 . C <*> 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 X 980 . T <*> 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 X 981 . T <*> 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 X 982 . G <*> 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 X 983 . A <*> 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 X 984 . G <*> 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 X 985 . C <*> 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 X 986 . C A,<*> 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 X 987 . C <*> 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 X 988 . A <*> 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 X 989 . G <*> 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 X 990 . G <*> 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 X 991 . A <*> 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 X 992 . G <*> 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 X 993 . T <*> 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 X 994 . T <*> 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 X 995 . C <*> 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 X 996 . A <*> 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 X 997 . A <*> 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 X 998 . G <*> 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 X 999 . G <*> 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 X 1000 . C <*> 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 X 1001 . T <*> 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 X 1002 . G <*> 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 X 1003 . C T,<*> 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 X 1004 . A <*> 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 X 1005 . A <*> 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 X 1006 . T <*> 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 X 1007 . G <*> 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 X 1008 . A <*> 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 X 1009 . G <*> 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 X 1010 . C <*> 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 X 1011 . T <*> 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 X 1012 . A <*> 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 X 1013 . T <*> 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 X 1014 . G <*> 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 X 1015 . A <*> 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 X 1016 . T <*> 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 X 1017 . T <*> 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 X 1018 . G <*> 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 X 1019 . C <*> 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 X 1020 . G <*> 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 X 1021 . C <*> 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 X 1022 . C <*> 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 X 1023 . A <*> 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 X 1024 . C <*> 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 X 1025 . T <*> 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 X 1026 . G <*> 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 X 1027 . C <*> 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 X 1028 . A <*> 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 X 1029 . C <*> 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 X 1030 . T <*> 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 X 1031 . T <*> 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 X 1032 . T <*> 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 X 1033 . G <*> 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 X 1034 . G <*> 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 X 1035 . C <*> 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 X 1036 . C <*> 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 X 1037 . T <*> 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 X 1038 . G <*> 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 X 1039 . G <*> 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 X 1040 . A <*> 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 X 1041 . C <*> 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 X 1042 . A <*> 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 X 1043 . A <*> 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 X 1044 . C <*> 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 X 1045 . A <*> 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 X 1046 . G <*> 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 X 1047 . A <*> 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 X 1048 . G <*> 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 X 1049 . C <*> 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 X 1050 . A <*> 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 X 1051 . A <*> 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 X 1052 . A <*> 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 X 1053 . A <*> 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 X 1054 . C <*> 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 X 1055 . C <*> 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 X 1056 . C <*> 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 X 1057 . T <*> 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 X 1058 . G <*> 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 X 1059 . T <*> 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 X 1060 . C <*> 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 X 1061 . T <*> 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 X 1062 . C A,<*> 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 X 1063 . T <*> 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 X 1064 . A <*> 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 X 1065 . A <*> 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 X 1066 . A <*> 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 X 1067 . A <*> 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 X 1068 . A <*> 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 X 1069 . A <*> 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 X 1070 . A <*> 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 X 1071 . G <*> 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 X 1072 . A <*> 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 X 1073 . A <*> 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 X 1074 . A <*> 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 X 1075 . A <*> 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 X 1076 . G <*> 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 X 1077 . A <*> 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 X 1078 . A <*> 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 X 1079 . A <*> 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 X 1080 . A <*> 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 X 1081 . G <*> 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 X 1082 . A <*> 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 X 1083 . A <*> 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 X 1084 . A <*> 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 X 1085 . A <*> 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 X 1086 . A <*> 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 X 1087 . C <*> 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 X 1088 . T <*> 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 X 1089 . C <*> 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 X 1090 . A <*> 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 X 1091 . C <*> 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 X 1092 . T <*> 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 X 1093 . G <*> 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 X 1094 . G <*> 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 X 1095 . A <*> 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 X 1096 . T <*> 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 X 1097 . A <*> 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 X 1098 . T <*> 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 X 1099 . G <*> 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 X 1100 . A <*> 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 X 1101 . A <*> 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 X 1102 . T <*> 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 X 1103 . G <*> 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 X 1104 . A <*> 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 X 1105 . T <*> 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 X 1106 . A <*> 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 X 1107 . C <*> 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 X 1108 . A <*> 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 X 1109 . G <*> 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 X 1110 . G <*> 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 X 1111 . T <*> 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 X 1112 . T <*> 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 X 1113 . G <*> 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 X 1114 . A <*> 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 X 1115 . G <*> 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 X 1116 . G <*> 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 X 1117 . A <*> 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 X 1118 . T <*> 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 X 1119 . C <*> 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 X 1120 . C <*> 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 X 1121 . A <*> 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 X 1122 . T <*> 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 X 1123 . T <*> 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 X 1124 . A <*> 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 X 1125 . T <*> 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 X 1126 . C <*> 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 X 1127 . T <*> 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 X 1128 . G <*> 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 X 1129 . A G,<*> 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 X 1130 . A <*> 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 X 1131 . A <*> 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 X 1132 . T <*> 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 X 1133 . G <*> 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 X 1134 . C <*> 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 X 1135 . T <*> 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 X 1136 . T <*> 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 X 1137 . G <*> 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 X 1138 . G <*> 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 X 1139 . A <*> 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 X 1140 . C <*> 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 X 1141 . C <*> 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 X 1142 . A <*> 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 X 1143 . G <*> 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 X 1144 . A <*> 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 X 1145 . T <*> 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 X 1146 . G <*> 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 X 1147 . T <*> 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 X 1148 . T <*> 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 X 1149 . T <*> 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 X 1150 . T <*> 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 X 1151 . G <*> 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 X 1152 . A <*> 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 X 1153 . A <*> 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 X 1154 . T <*> 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 X 1155 . T <*> 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 X 1156 . T <*> 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 X 1157 . T <*> 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 X 1158 . G <*> 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 X 1159 . G <*> 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 X 1160 . A <*> 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 X 1161 . T <*> 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 X 1162 . T <*> 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 X 1163 . T <*> 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 X 1164 . T <*> 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 X 1165 . T <*> 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 X 1166 . T <*> 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 X 1167 . C <*> 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 X 1168 . A <*> 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 X 1169 . T <*> 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 X 1170 . A <*> 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 X 1171 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 X 1172 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 X 1173 . T <*> 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 X 1174 . T <*> 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 X 1175 . G <*> 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 X 1176 . T <*> 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 X 1177 . A <*> 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 X 1178 . A <*> 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 X 1179 . T <*> 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 X 1180 . C <*> 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 X 1181 . T <*> 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 X 1182 . T <*> 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 X 1183 . T <*> 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 X 1184 . G <*> 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 X 1185 . C <*> 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 X 1186 . A <*> 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 X 1187 . G <*> 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 X 1188 . T <*> 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 X 1189 . A <*> 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 X 1190 . T <*> 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 X 1191 . A <*> 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 X 1192 . T <*> 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 X 1193 . T <*> 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 X 1194 . T <*> 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 X 1195 . A <*> 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 X 1196 . C <*> 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 X 1197 . C <*> 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 X 1198 . A <*> 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 X 1199 . G <*> 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 X 1200 . T <*> 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 X 1201 . T <*> 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 X 1202 . C <*> 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 X 1203 . A <*> 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 X 1204 . G <*> 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 X 1205 . C <*> 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 X 1206 . A <*> 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 X 1207 . T <*> 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 X 1208 . C <*> 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 X 1209 . C T,<*> 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 X 1210 . C <*> 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 X 1211 . T <*> 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 X 1212 . A <*> 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 X 1213 . A <*> 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 X 1214 . C <*> 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 X 1215 . T <*> 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 X 1216 . C <*> 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 X 1217 . A <*> 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 X 1218 . A <*> 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 X 1219 . A <*> 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 X 1220 . A <*> 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 X 1221 . A <*> 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 X 1222 . T <*> 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 X 1223 . T <*> 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 X 1224 . C <*> 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 X 1225 . A <*> 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 X 1226 . A <*> 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 X 1227 . A <*> 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 X 1228 . A <*> 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 X 1229 . A <*> 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 X 1230 . T <*> 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 X 1231 . C <*> 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 X 1232 . T <*> 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 X 1233 . G <*> 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 X 1234 . A <*> 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 X 1235 . A <*> 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 X 1236 . A <*> 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 X 1237 . T <*> 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 X 1238 . C <*> 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 X 1239 . C <*> 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 X 1240 . C <*> 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 X 1241 . A <*> 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 X 1242 . A <*> 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 X 1243 . A <*> 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 X 1244 . C <*> 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 X 1245 . G <*> 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 X 1246 . C <*> 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 X 1247 . G <*> 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 X 1248 . C <*> 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 X 1249 . C <*> 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 X 1250 . A <*> 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 X 1251 . A <*> 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 X 1252 . T <*> 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 X 1253 . A <*> 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 X 1254 . A <*> 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 X 1255 . G <*> 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 X 1256 . C <*> 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 X 1257 . A <*> 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 X 1258 . T <*> 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 X 1259 . T <*> 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 X 1260 . C <*> 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 X 1261 . C <*> 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 X 1262 . C <*> 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 X 1263 . T <*> 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 X 1264 . T <*> 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 X 1265 . T <*> 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 X 1266 . G <*> 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 X 1267 . A <*> 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 X 1268 . G <*> 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 X 1269 . C <*> 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 X 1270 . G <*> 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 X 1271 . T <*> 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 X 1272 . C <*> 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 X 1273 . A <*> 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 X 1274 . T <*> 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 X 1275 . G <*> 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 X 1276 . T <*> 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 X 1277 . C <*> 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 X 1278 . G <*> 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 X 1279 . G <*> 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 X 1280 . T <*> 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 X 1281 . G <*> 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 X 1282 . C <*> 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 X 1283 . T <*> 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 X 1284 . T <*> 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 X 1285 . G <*> 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 X 1286 . G <*> 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 X 1287 . A <*> 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 X 1288 . A <*> 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 X 1289 . T <*> 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 X 1290 . G <*> 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 X 1291 . T <*> 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 X 1292 . T <*> 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 X 1293 . T <*> 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 X 1294 . G <*> 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 X 1295 . G <*> 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 X 1296 . G <*> 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 X 1297 . G <*> 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 X 1298 . T <*> 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 X 1299 . T <*> 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 X 1300 . T <*> 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 X 1301 . T G,<*> 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 X 1302 . G <*> 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 X 1303 . G <*> 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 X 1304 . A <*> 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 X 1305 . T <*> 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 X 1306 . T <*> 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 X 1307 . T <*> 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 X 1308 . A <*> 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 X 1309 . C <*> 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 X 1310 . A <*> 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 X 1311 . G <*> 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 X 1312 . C <*> 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 X 1313 . T <*> 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 X 1314 . T <*> 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 X 1315 . T <*> 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 X 1316 . G <*> 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 X 1317 . G <*> 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 X 1318 . G <*> 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 X 1319 . A <*> 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 X 1320 . C <*> 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 X 1321 . G <*> 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 X 1322 . C <*> 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 X 1323 . T <*> 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 X 1324 . C <*> 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 X 1325 . A <*> 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 X 1326 . A <*> 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 X 1327 . C <*> 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 X 1328 . C <*> 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 X 1329 . T <*> 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 X 1330 . G <*> 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 X 1331 . T <*> 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 X 1332 . A <*> 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 X 1333 . C <*> 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 X 1334 . C <*> 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 X 1335 . T <*> 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 X 1336 . C <*> 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 X 1337 . A <*> 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 X 1338 . A <*> 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 X 1339 . T <*> 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 X 1340 . A <*> 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 X 1341 . A <*> 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 X 1342 . A <*> 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 X 1343 . C <*> 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 X 1344 . C <*> 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 X 1345 . T <*> 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 X 1346 . G <*> 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 X 1347 . A <*> 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 X 1348 . T <*> 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 X 1349 . T <*> 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 X 1350 . T <*> 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 X 1351 . T <*> 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 X 1352 . A <*> 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 X 1353 . A <*> 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 X 1354 . A <*> 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 X 1355 . A <*> 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 X 1356 . A <*> 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 X 1357 . A <*> 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 X 1358 . G <*> 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 X 1359 . T <*> 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 X 1360 . T <*> 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 X 1361 . T <*> 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 X 1362 . G <*> 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 X 1363 . G <*> 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 X 1364 . G <*> 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 X 1365 . G <*> 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 X 1366 . G <*> 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 X 1367 . G C,<*> 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 X 1368 . A <*> 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 X 1369 . T <*> 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 X 1370 . T <*> 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 X 1371 . C <*> 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 X 1372 . C <*> 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 X 1373 . C <*> 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 X 1374 . C <*> 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 X 1375 . T <*> 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 X 1376 . A <*> 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 X 1377 . A <*> 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 X 1378 . G <*> 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 X 1379 . C <*> 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 X 1380 . C <*> 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 X 1381 . C <*> 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 X 1382 . G <*> 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 X 1383 . C <*> 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 X 1384 . C <*> 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 X 1385 . A <*> 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 X 1386 . C <*> 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 X 1387 . C <*> 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 X 1388 . C <*> 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 X 1389 . G <*> 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 X 1390 . G <*> 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 X 1391 . A <*> 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 X 1392 . G <*> 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 X 1393 . A <*> 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 X 1394 . C <*> 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 X 1395 . A <*> 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 X 1396 . G <*> 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 X 1397 . C <*> 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 X 1398 . G <*> 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 X 1399 . G <*> 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 X 1400 . A <*> 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 X 1401 . T <*> 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 X 1402 . T <*> 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 X 1403 . T <*> 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 X 1404 . C <*> 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 X 1405 . C <*> 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 X 1406 . T <*> 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 X 1407 . T <*> 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 X 1408 . A <*> 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 X 1409 . G <*> 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 X 1410 . T <*> 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 X 1411 . T <*> 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 X 1412 . A T,<*> 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 X 1413 . C <*> 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 X 1414 . T <*> 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 X 1415 . T <*> 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 X 1416 . A <*> 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 X 1417 . C <*> 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 X 1418 . T <*> 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 X 1419 . A <*> 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 X 1420 . T <*> 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 X 1421 . G <*> 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 X 1422 . C <*> 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 X 1423 . T <*> 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 X 1424 . C <*> 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 X 1425 . C <*> 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 X 1426 . T <*> 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 X 1427 . T <*> 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 X 1428 . G <*> 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 X 1429 . G <*> 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 X 1430 . C <*> 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 X 1431 . C <*> 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 X 1432 . A <*> 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 X 1433 . T <*> 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 X 1434 . T <*> 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 X 1435 . T <*> 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 X 1436 . C <*> 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 X 1437 . T <*> 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 X 1438 . C <*> 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 X 1439 . T <*> 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 X 1440 . A <*> 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 X 1441 . G <*> 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 X 1442 . G <*> 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 X 1443 . T <*> 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 X 1444 . A <*> 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 X 1445 . T <*> 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 X 1446 . T <*> 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 X 1447 . G <*> 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 X 1448 . G <*> 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 X 1449 . T <*> 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 X 1450 . A <*> 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 X 1451 . T <*> 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 X 1452 . A <*> 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 X 1453 . T <*> 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 X 1454 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 X 1455 . G <*> 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 X 1456 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 X 1457 . G <*> 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 X 1458 . T <*> 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 X 1459 . C A,<*> 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 X 1460 . T <*> 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 X 1461 . G <*> 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 X 1462 . C <*> 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 X 1463 . T <*> 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 X 1464 . G <*> 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 X 1465 . T <*> 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 X 1466 . G <*> 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 X 1467 . A <*> 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 X 1468 . A <*> 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 X 1469 . C T,<*> 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 X 1470 . T <*> 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 X 1471 . G <*> 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 X 1472 . T <*> 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 X 1473 . C <*> 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 X 1474 . C <*> 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 X 1475 . T <*> 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 X 1476 . T G,<*> 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 X 1477 . G <*> 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 X 1478 . G <*> 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 X 1479 . C <*> 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 X 1480 . C <*> 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 X 1481 . T <*> 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 X 1482 . G <*> 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 X 1483 . T <*> 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 X 1484 . T <*> 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 X 1485 . T <*> 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 X 1486 . G <*> 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 X 1487 . G <*> 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 X 1488 . T <*> 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 X 1489 . G <*> 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 X 1490 . A <*> 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 X 1491 . C <*> 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 X 1492 . G <*> 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 X 1493 . G <*> 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 X 1494 . G <*> 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 X 1495 . T <*> 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 X 1496 . G <*> 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 X 1497 . A <*> 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 X 1498 . G <*> 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 X 1499 . G <*> 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 X 1500 . A <*> 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 X 1501 . G <*> 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 X 1502 . C <*> 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 X 1503 . A <*> 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 X 1504 . G <*> 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 X 1505 . G <*> 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 X 1506 . G <*> 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 X 1507 . A <*> 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 X 1508 . C <*> 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 X 1509 . A <*> 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 X 1510 . G <*> 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 X 1511 . A <*> 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 X 1512 . A <*> 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 X 1513 . G <*> 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 X 1514 . G <*> 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 X 1515 . G <*> 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 X 1516 . T <*> 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 X 1517 . C <*> 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 X 1518 . C <*> 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 X 1519 . T <*> 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 X 1520 . G <*> 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 X 1521 . C <*> 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 X 1522 . G <*> 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 X 1523 . T <*> 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 X 1524 . G <*> 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 X 1525 . C <*> 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 X 1526 . C <*> 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 X 1527 . C <*> 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 X 1528 . T <*> 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 X 1529 . G <*> 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 X 1530 . C <*> 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 X 1531 . C <*> 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 X 1532 . T <*> 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 X 1533 . T <*> 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 X 1534 . C <*> 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 X 1535 . A <*> 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 X 1536 . C <*> 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 X 1537 . A <*> 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 X 1538 . A <*> 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 X 1539 . G <*> 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 X 1540 . C <*> 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 X 1541 . C <*> 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 X 1542 . C <*> 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 X 1543 . C <*> 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 X 1544 . T <*> 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 X 1545 . G <*> 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 X 1546 . G <*> 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 X 1547 . A <*> 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 X 1548 . A <*> 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 X 1549 . G <*> 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 X 1550 . G <*> 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 X 1551 . A <*> 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 X 1552 . A <*> 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 X 1553 . A <*> 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 X 1554 . G <*> 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 X 1555 . T <*> 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 X 1556 . T <*> 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 X 1557 . G <*> 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 X 1558 . T <*> 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 X 1559 . T <*> 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 X 1560 . T <*> 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 X 1561 . T <*> 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 X 1562 . G <*> 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 X 1563 . G <*> 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 X 1564 . G <*> 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 X 1565 . A <*> 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 X 1566 . T <*> 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 X 1567 . C <*> 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 X 1568 . T <*> 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 X 1569 . C <*> 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 X 1570 . T <*> 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 X 1571 . G <*> 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 X 1572 . C <*> 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 X 1573 . A <*> 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 X 1574 . C <*> 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 X 1575 . C <*> 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 X 1576 . C <*> 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 X 1577 . T <*> 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 X 1578 . C <*> 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 X 1579 . A <*> 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 X 1580 . G <*> 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 X 1581 . C <*> 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 X 1582 . C <*> 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 X 1583 . T <*> 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 X 1584 . G <*> 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 X 1585 . G <*> 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 X 1586 . A <*> 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 X 1587 . C <*> 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 X 1588 . A <*> 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 X 1589 . A <*> 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 X 1590 . C <*> 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 X 1591 . T <*> 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 X 1592 . T <*> 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 X 1593 . G <*> 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 X 1594 . T <*> 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 X 1595 . G <*> 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 X 1596 . C <*> 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 X 1597 . C <*> 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 X 1598 . C <*> 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 X 1599 . A <*> 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 X 1600 . T <*> 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 X 1601 . C <*> 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 X 1602 . T <*> 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 X 1603 . G <*> 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 X 1604 . G <*> 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 X 1605 . T <*> 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 X 1606 . G <*> 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 X 1607 . A <*> 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 X 1608 . C <*> 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 X 1609 . C <*> 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 X 1610 . C <*> 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 X 1611 . C <*> 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 X 1612 . T <*> 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 X 1613 . C <*> 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 X 1614 . A <*> 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 X 1615 . C <*> 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 X 1616 . T <*> 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 X 1617 . C <*> 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 X 1618 . A <*> 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 X 1619 . G <*> 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 X 1620 . C <*> 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 X 1621 . C <*> 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 X 1622 . A <*> 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 X 1623 . C <*> 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 X 1624 . C <*> 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 X 1625 . A <*> 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 X 1626 . G <*> 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 X 1627 . A <*> 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 X 1628 . C <*> 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 X 1629 . T <*> 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 X 1630 . T <*> 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 X 1631 . C <*> 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 X 1632 . C <*> 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 X 1633 . A <*> 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 X 1634 . C <*> 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 X 1635 . G <*> 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 X 1636 . A <*> 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 X 1637 . C <*> 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 X 1638 . A <*> 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 X 1639 . G <*> 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 X 1640 . G <*> 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 X 1641 . C <*> 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 X 1642 . T <*> 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 X 1643 . C <*> 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 X 1644 . C <*> 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 X 1645 . A <*> 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 X 1646 . G <*> 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 X 1647 . C <*> 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 X 1648 . C <*> 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 X 1649 . T <*> 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 X 1650 . C <*> 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 X 1651 . G <*> 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 X 1652 . G <*> 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 X 1653 . C <*> 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 X 1654 . A T,<*> 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 X 1655 . C <*> 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 X 1656 . C <*> 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 X 1657 . T A,<*> 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 X 1658 . T <*> 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 X 1659 . C <*> 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 X 1660 . A <*> 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 X 1661 . G <*> 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 X 1662 . C <*> 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 X 1663 . C <*> 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 X 1664 . A C,<*> 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 X 1665 . T C,<*> 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 X 1666 . G <*> 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 X 1667 . G <*> 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 X 1668 . A <*> 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 X 1669 . C <*> 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 X 1670 . A <*> 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 X 1671 . G <*> 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 X 1672 . T <*> 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 X 1673 . T <*> 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 X 1674 . C <*> 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 X 1675 . C <*> 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 X 1676 . G <*> 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 X 1677 . C <*> 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 X 1678 . C <*> 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 X 1679 . A <*> 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 X 1680 . G <*> 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 X 1681 . C <*> 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 X 1682 . G <*> 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 X 1683 . T <*> 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 X 1684 . T <*> 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 X 1685 . G <*> 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 X 1686 . C <*> 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 X 1687 . C <*> 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 X 1688 . C <*> 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 X 1689 . T A,<*> 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 X 1690 . C <*> 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 X 1691 . T <*> 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 X 1692 . G <*> 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 X 1693 . T <*> 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 X 1694 . T <*> 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 X 1695 . C <*> 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 X 1696 . T <*> 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 X 1697 . G <*> 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 X 1698 . C A,<*> 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 X 1699 . T <*> 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 X 1700 . G <*> 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 X 1701 . T <*> 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 X 1702 . T <*> 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 X 1703 . T <*> 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 X 1704 . T <*> 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 X 1705 . C <*> 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 X 1706 . T <*> 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 X 1707 . C <*> 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 X 1708 . T <*> 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 X 1709 . A <*> 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 X 1710 . C <*> 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 X 1711 . C <*> 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 X 1712 . A <*> 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 X 1713 . G <*> 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 X 1714 . A <*> 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 X 1715 . A <*> 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 X 1716 . G <*> 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 X 1717 . T <*> 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 X 1718 . G <*> 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 X 1719 . C <*> 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 X 1720 . C <*> 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 X 1721 . C <*> 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 X 1722 . T <*> 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 X 1723 . T <*> 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 X 1724 . C <*> 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 X 1725 . C G,<*> 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 X 1726 . C <*> 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 X 1727 . T <*> 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 X 1728 . C <*> 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 X 1729 . C <*> 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 X 1730 . T <*> 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 X 1731 . C <*> 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 X 1732 . A <*> 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 X 1733 . C <*> 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 X 1734 . C <*> 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 X 1735 . T <*> 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 X 1736 . G <*> 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 X 1737 . A <*> 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 X 1738 . C <*> 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 X 1739 . C <*> 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 X 1740 . A <*> 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 X 1741 . C <*> 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 X 1742 . T <*> 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 X 1743 . C <*> 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 X 1744 . T <*> 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 X 1745 . G <*> 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 X 1746 . G <*> 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 X 1747 . G <*> 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 X 1748 . G <*> 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 X 1749 . A <*> 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 X 1750 . A <*> 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 X 1751 . A <*> 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 X 1752 . T <*> 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 X 1753 . C <*> 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 X 1754 . C <*> 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 X 1755 . C <*> 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 X 1756 . T <*> 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 X 1757 . C <*> 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 X 1758 . A <*> 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 X 1759 . G <*> 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 X 1760 . C <*> 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 X 1761 . A <*> 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 X 1762 . C <*> 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 X 1763 . C <*> 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 X 1764 . C <*> 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 X 1765 . T <*> 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 X 1766 . C <*> 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 X 1767 . C <*> 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 X 1768 . C <*> 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 X 1769 . T <*> 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 X 1770 . G <*> 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 X 1771 . A <*> 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 X 1772 . G <*> 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 X 1773 . C <*> 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 X 1774 . A <*> 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 X 1775 . T <*> 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 X 1776 . A <*> 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 X 1777 . C <*> 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 X 1778 . C <*> 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 X 1779 . C <*> 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 X 1780 . T <*> 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 X 1781 . A <*> 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 X 1782 . C <*> 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 X 1783 . T <*> 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 X 1784 . C <*> 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 X 1785 . T <*> 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 X 1786 . G <*> 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 X 1787 . G <*> 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 X 1788 . C <*> 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 X 1789 . A <*> 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 X 1790 . C <*> 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 X 1791 . A <*> 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 X 1792 . A <*> 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 X 1793 . G <*> 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 X 1794 . C <*> 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 X 1795 . C <*> 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 X 1796 . C <*> 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 X 1797 . A <*> 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 X 1798 . C <*> 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 X 1799 . C <*> 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 X 1800 . C <*> 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 X 1801 . T <*> 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 X 1802 . G <*> 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 X 1803 . C <*> 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 X 1804 . A <*> 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 X 1805 . A <*> 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 X 1806 . A <*> 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 X 1807 . G <*> 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 X 1808 . C <*> 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 X 1809 . C <*> 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 X 1810 . C <*> 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 X 1811 . C <*> 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 X 1812 . T <*> 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 X 1813 . G <*> 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 X 1814 . A <*> 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 X 1815 . G <*> 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 X 1816 . G <*> 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 X 1817 . C <*> 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 X 1818 . C <*> 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 X 1819 . C <*> 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 X 1820 . G <*> 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 X 1821 . C <*> 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 X 1822 . C <*> 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 X 1823 . C <*> 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 X 1824 . T <*> 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 X 1825 . G <*> 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 X 1826 . T <*> 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 X 1827 . G <*> 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 X 1828 . G <*> 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 X 1829 . C <*> 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 X 1830 . G <*> 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 X 1831 . T <*> 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 X 1832 . C <*> 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 X 1833 . T <*> 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 X 1834 . C <*> 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 X 1835 . T <*> 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 X 1836 . C <*> 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 X 1837 . C <*> 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 X 1838 . C <*> 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 X 1839 . T <*> 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 X 1840 . C <*> 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 X 1841 . C <*> 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 X 1842 . C <*> 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 X 1843 . T <*> 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 X 1844 . T <*> 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 X 1845 . G <*> 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 X 1846 . C <*> 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 X 1847 . T <*> 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 X 1848 . G <*> 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 X 1849 . T <*> 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 X 1850 . C <*> 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 X 1851 . A <*> 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 X 1852 . G <*> 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 X 1853 . G <*> 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 X 1854 . A <*> 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 X 1855 . C <*> 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 X 1856 . A <*> 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 X 1857 . G <*> 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 X 1858 . T <*> 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 X 1859 . G <*> 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 X 1860 . G <*> 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 X 1861 . T <*> 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 X 1862 . C <*> 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 X 1863 . C <*> 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 X 1864 . T <*> 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 X 1865 . G <*> 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 X 1866 . G <*> 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 X 1867 . C <*> 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 X 1868 . C <*> 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 X 1869 . A T,<*> 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 X 1870 . C <*> 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 X 1871 . C <*> 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 X 1872 . G <*> 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 X 1873 . G <*> 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 X 1874 . G <*> 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 X 1875 . G <*> 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 X 1876 . C <*> 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 X 1877 . T <*> 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 X 1878 . C <*> 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 X 1879 . A <*> 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 X 1880 . C <*> 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 X 1881 . G <*> 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 X 1882 . G <*> 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 X 1883 . A <*> 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 X 1884 . G <*> 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 X 1885 . C <*> 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 X 1886 . C <*> 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 X 1887 . G <*> 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 X 1888 . C <*> 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 X 1889 . C <*> 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 X 1890 . C <*> 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 X 1891 . T <*> 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 X 1892 . G <*> 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 X 1893 . T <*> 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 X 1894 . G <*> 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 X 1895 . C <*> 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 X 1896 . C <*> 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 X 1897 . G <*> 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 X 1898 . T <*> 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 X 1899 . G <*> 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 X 1900 . T <*> 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 X 1901 . A <*> 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 X 1902 . C <*> 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 X 1903 . C <*> 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 X 1904 . T <*> 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 X 1905 . C <*> 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 X 1906 . T <*> 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 X 1907 . G <*> 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 X 1908 . A <*> 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 X 1909 . G <*> 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 X 1910 . C <*> 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 X 1911 . C <*> 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 X 1912 . C <*> 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 X 1913 . T <*> 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 X 1914 . C <*> 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 X 1915 . T C,<*> 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 X 1916 . G T,<*> 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 X 1917 . C <*> 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 X 1918 . A <*> 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 X 1919 . C <*> 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 X 1920 . A T,<*> 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 X 1921 . G <*> 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 X 1922 . T <*> 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 X 1923 . G <*> 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 X 1924 . C <*> 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 X 1925 . C <*> 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 X 1926 . T <*> 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 X 1927 . T <*> 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 X 1928 . C <*> 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 X 1929 . T <*> 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 X 1930 . G <*> 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 X 1931 . C <*> 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 X 1932 . T <*> 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 X 1933 . T <*> 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 X 1934 . G <*> 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 X 1935 . C <*> 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 X 1936 . C <*> 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 X 1937 . T <*> 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 X 1938 . G <*> 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 X 1939 . T <*> 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 X 1940 . G <*> 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 X 1941 . G <*> 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 X 1942 . C <*> 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 X 1943 . T <*> 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 X 1944 . T <*> 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 X 1945 . T <*> 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 X 1946 . G <*> 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 X 1947 . A <*> 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 X 1948 . G C,<*> 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 X 1949 . A <*> 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 X 1950 . A <*> 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 X 1951 . G <*> 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 X 1952 . A <*> 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 X 1953 . A <*> 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 X 1954 . A C,<*> 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 X 1955 . C <*> 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 X 1956 . C <*> 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 X 1957 . C <*> 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 X 1958 . C <*> 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 X 1959 . T <*> 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 X 1960 . T <*> 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 X 1961 . C <*> 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 X 1962 . T <*> 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 X 1963 . G <*> 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 X 1964 . G <*> 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 X 1965 . T <*> 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 X 1966 . T <*> 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 X 1967 . A <*> 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 X 1968 . T <*> 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 X 1969 . A <*> 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 X 1970 . C <*> 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 X 1971 . A <*> 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 X 1972 . T <*> 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 X 1973 . A <*> 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 X 1974 . A <*> 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 X 1975 . G <*> 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 X 1976 . A <*> 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 X 1977 . C <*> 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 X 1978 . A <*> 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 X 1979 . G <*> 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 X 1980 . C <*> 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 X 1981 . C <*> 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 X 1982 . A <*> 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 X 1983 . G <*> 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 X 1984 . A <*> 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 X 1985 . G <*> 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 X 1986 . A <*> 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 X 1987 . A <*> 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 X 1988 . G <*> 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 X 1989 . G <*> 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 X 1990 . G T,<*> 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 X 1991 . A <*> 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 X 1992 . G <*> 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 X 1993 . T <*> 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 X 1994 . T <*> 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 X 1995 . G <*> 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 X 1996 . C <*> 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 X 1997 . C <*> 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 X 1998 . C <*> 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 X 1999 . A <*> 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 X 2000 . G <*> 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 X 2001 . G <*> 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 X 2002 . G <*> 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 X 2003 . T <*> 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 X 2004 . G <*> 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 X 2005 . G <*> 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 X 2006 . C <*> 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 X 2007 . A <*> 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 X 2008 . C <*> 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 X 2009 . A <*> 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 X 2010 . G <*> 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 X 2011 . C <*> 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 X 2012 . A <*> 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 X 2013 . C <*> 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 X 2014 . G <*> 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 X 2015 . T <*> 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 X 2016 . T <*> 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 X 2017 . G <*> 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 X 2018 . C <*> 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 X 2019 . T <*> 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 X 2020 . G <*> 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 X 2021 . C <*> 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 X 2022 . C <*> 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 X 2023 . A <*> 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 X 2024 . G <*> 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 X 2025 . T <*> 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 X 2026 . T <*> 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 X 2027 . A <*> 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 X 2028 . C <*> 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 X 2029 . T <*> 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 X 2030 . G <*> 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 X 2031 . C <*> 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 X 2032 . C <*> 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 X 2033 . A <*> 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 X 2034 . T <*> 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 X 2035 . T <*> 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 X 2036 . T <*> 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 X 2037 . T <*> 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 X 2038 . C <*> 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 X 2039 . A <*> 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 X 2040 . C <*> 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 X 2041 . G A,<*> 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 X 2042 . G <*> 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 X 2043 . G <*> 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 X 2044 . C <*> 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 X 2045 . A <*> 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 X 2046 . T <*> 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 X 2047 . G <*> 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 X 2048 . A <*> 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 X 2049 . A <*> 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 X 2050 . A <*> 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 X 2051 . T <*> 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 X 2052 . G <*> 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 X 2053 . G T,<*> 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 X 2054 . A <*> 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 X 2055 . G <*> 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 X 2056 . A <*> 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 X 2057 . T <*> 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 X 2058 . A <*> 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 X 2059 . A <*> 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 X 2060 . C <*> 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 X 2061 . A <*> 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 X 2062 . A <*> 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 X 2063 . C <*> 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 X 2064 . A <*> 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 X 2065 . G <*> 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 X 2066 . G <*> 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 X 2067 . A <*> 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 X 2068 . G <*> 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 X 2069 . C <*> 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 X 2070 . G <*> 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 X 2071 . A <*> 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 X 2072 . C <*> 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 X 2073 . C <*> 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 X 2074 . G <*> 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 X 2075 . C <*> 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 X 2076 . A <*> 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 X 2077 . C <*> 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 X 2078 . A <*> 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 X 2079 . G <*> 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 X 2080 . G <*> 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 X 2081 . C <*> 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 X 2082 . T <*> 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 X 2083 . G <*> 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 X 2084 . C <*> 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 X 2085 . T <*> 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 X 2086 . G <*> 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 X 2087 . A <*> 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 X 2088 . G <*> 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 X 2089 . C <*> 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 X 2090 . G <*> 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 X 2091 . C <*> 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 X 2092 . G <*> 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 X 2093 . T G,<*> 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 X 2094 . C <*> 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 X 2095 . A <*> 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 X 2096 . C <*> 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 X 2097 . A <*> 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 X 2098 . C <*> 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 X 2099 . G <*> 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 X 2100 . C <*> 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 X 2101 . A <*> 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 X 2102 . G <*> 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 X 2103 . C <*> 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 X 2104 . C <*> 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 X 2105 . A <*> 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 X 2106 . T <*> 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 X 2107 . C <*> 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 X 2108 . G <*> 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 X 2109 . C <*> 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 X 2110 . G <*> 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 X 2111 . C <*> 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 X 2112 . A <*> 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 X 2113 . G <*> 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 X 2114 . C <*> 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 X 2115 . T <*> 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 X 2116 . C <*> 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 X 2117 . A <*> 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 X 2118 . G <*> 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 X 2119 . G <*> 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 X 2120 . G <*> 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 X 2121 . A <*> 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 X 2122 . T <*> 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 X 2123 . A <*> 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 X 2124 . T <*> 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 X 2125 . T <*> 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 X 2126 . A <*> 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 X 2127 . C <*> 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 X 2128 . G <*> 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 X 2129 . T <*> 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 X 2130 . G <*> 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 X 2131 . T <*> 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 X 2132 . A <*> 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 X 2133 . A <*> 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 X 2134 . C <*> 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 X 2135 . T <*> 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 X 2136 . C <*> 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 X 2137 . G <*> 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 X 2138 . A <*> 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 X 2139 . C <*> 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 X 2140 . A <*> 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 X 2141 . T <*> 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 X 2142 . G <*> 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 X 2143 . T <*> 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 X 2144 . C <*> 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 X 2145 . A <*> 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 X 2146 . G <*> 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 X 2147 . C <*> 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 X 2148 . G <*> 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 X 2149 . A <*> 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 X 2150 . T <*> 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 X 2151 . T <*> 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 X 2152 . G <*> 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 X 2153 . T <*> 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 X 2154 . C <*> 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 X 2155 . A <*> 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 X 2156 . C <*> 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 X 2157 . A <*> 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 X 2158 . G <*> 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 X 2159 . G <*> 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 X 2160 . C <*> 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 X 2161 . A <*> 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 X 2162 . C <*> 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 X 2163 . T <*> 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 X 2164 . G <*> 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 X 2165 . C <*> 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 X 2166 . T <*> 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 X 2167 . A <*> 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 X 2168 . C <*> 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 X 2169 . T <*> 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 X 2170 . C <*> 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 X 2171 . C <*> 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 X 2172 . T <*> 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 X 2173 . G <*> 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 X 2174 . G <*> 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 X 2175 . G <*> 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 X 2176 . G <*> 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 X 2177 . T <*> 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 X 2178 . T <*> 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 X 2179 . T <*> 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 X 2180 . T <*> 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 X 2181 . C <*> 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 X 2182 . C <*> 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 X 2183 . A <*> 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 X 2184 . T <*> 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 X 2185 . C <*> 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 X 2186 . A <*> 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 X 2187 . A <*> 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 X 2188 . A <*> 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 X 2189 . C <*> 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 X 2190 . C <*> 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 X 2191 . C <*> 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 X 2192 . T <*> 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 X 2193 . C <*> 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 X 2194 . A <*> 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 X 2195 . A <*> 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 X 2196 . G <*> 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 X 2197 . A <*> 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 X 2198 . G <*> 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 X 2199 . C <*> 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 X 2200 . T <*> 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 X 2201 . G <*> 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 X 2202 . G <*> 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 X 2203 . G <*> 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 X 2204 . C <*> 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 X 2205 . C <*> 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 X 2206 . T <*> 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 X 2207 . G <*> 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 X 2208 . G <*> 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 X 2209 . G <*> 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 X 2210 . G C,<*> 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 X 2211 . T <*> 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 X 2212 . C <*> 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 X 2213 . A <*> 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 X 2214 . A <*> 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 X 2215 . C <*> 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 X 2216 . T <*> 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 X 2217 . T <*> 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 X 2218 . C <*> 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 X 2219 . C <*> 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 X 2220 . G A,<*> 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 X 2221 . G <*> 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 X 2222 . C <*> 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 X 2223 . C <*> 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 X 2224 . T <*> 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 X 2225 . G <*> 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 X 2226 . G <*> 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 X 2227 . G <*> 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 X 2228 . G C,<*> 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 X 2229 . A <*> 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 X 2230 . A <*> 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 X 2231 . A <*> 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 X 2232 . C <*> 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 X 2233 . T <*> 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 X 2234 . G <*> 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 X 2235 . G <*> 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 X 2236 . G <*> 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 X 2237 . G <*> 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 X 2238 . C <*> 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 X 2239 . A <*> 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 X 2240 . A <*> 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 X 2241 . G <*> 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 X 2242 . T <*> 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 X 2243 . A <*> 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 X 2244 . T <*> 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 X 2245 . C <*> 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 X 2246 . A <*> 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 X 2247 . C <*> 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 X 2248 . C <*> 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 X 2249 . A <*> 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 X 2250 . G <*> 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 X 2251 . A <*> 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 X 2252 . G <*> 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 X 2253 . A <*> 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 X 2254 . T <*> 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 X 2255 . G <*> 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 X 2256 . A <*> 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 X 2257 . G <*> 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 X 2258 . C <*> 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 X 2259 . T <*> 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 X 2260 . T <*> 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 X 2261 . T <*> 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 X 2262 . A <*> 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 X 2263 . T <*> 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 X 2264 . A <*> 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 X 2265 . A <*> 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 X 2266 . A <*> 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 X 2267 . A <*> 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 X 2268 . A <*> 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 X 2269 . T <*> 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 X 2270 . A <*> 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 X 2271 . A <*> 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 X 2272 . T <*> 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 X 2273 . G <*> 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 X 2274 . G <*> 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 X 2275 . T <*> 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 X 2276 . G <*> 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 X 2277 . C <*> 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 X 2278 . T <*> 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 X 2279 . A <*> 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 X 2280 . G <*> 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 X 2281 . C <*> 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 X 2282 . T <*> 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 X 2283 . G <*> 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 X 2284 . G <*> 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 X 2285 . G <*> 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 X 2286 . C <*> 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 X 2287 . A <*> 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 X 2288 . T <*> 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 X 2289 . G <*> 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 X 2290 . G <*> 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 X 2291 . T <*> 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 X 2292 . G <*> 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 X 2293 . G <*> 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 X 2294 . C <*> 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 X 2295 . T <*> 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 X 2296 . T <*> 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 X 2297 . G <*> 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 X 2298 . C <*> 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 X 2299 . A <*> 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 X 2300 . C <*> 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 X 2301 . C <*> 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 X 2302 . T <*> 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 X 2303 . G <*> 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 X 2304 . T <*> 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 X 2305 . A <*> 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 X 2306 . A <*> 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 X 2307 . T <*> 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 X 2308 . C <*> 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 X 2309 . C A,<*> 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 X 2310 . C <*> 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 X 2311 . A <*> 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 X 2312 . G <*> 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 X 2313 . C <*> 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 X 2314 . A <*> 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 X 2315 . C <*> 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 X 2316 . T <*> 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 X 2317 . T <*> 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 X 2318 . T <*> 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 X 2319 . G <*> 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 X 2320 . G <*> 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 X 2321 . G <*> 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 X 2322 . A <*> 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 X 2323 . G <*> 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 X 2324 . G <*> 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 X 2325 . C <*> 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 X 2326 . C <*> 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 X 2327 . G <*> 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 X 2328 . A <*> 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 X 2329 . G <*> 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 X 2330 . C <*> 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 X 2331 . T <*> 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 X 2332 . A <*> 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 X 2333 . G <*> 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 X 2334 . G <*> 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 X 2335 . A <*> 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 X 2336 . G <*> 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 X 2337 . G <*> 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 X 2338 . A <*> 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 X 2339 . T <*> 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 X 2340 . C <*> 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 X 2341 . G <*> 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 X 2342 . T <*> 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 X 2343 . T <*> 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 X 2344 . T <*> 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 X 2345 . G <*> 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 X 2346 . A <*> 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 X 2347 . G <*> 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 X 2348 . T <*> 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 X 2349 . C <*> 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 X 2350 . C <*> 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 X 2351 . A <*> 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 X 2352 . G <*> 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 X 2353 . C <*> 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 X 2354 . A <*> 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 X 2355 . G <*> 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 X 2356 . T <*> 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 X 2357 . T <*> 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 X 2358 . T <*> 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 X 2359 . G <*> 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 X 2360 . A <*> 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 X 2361 . G <*> 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 X 2362 . A <*> 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 X 2363 . C <*> 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 X 2364 . C <*> 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 X 2365 . A <*> 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 X 2366 . G <*> 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 X 2367 . C <*> 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 X 2368 . C <*> 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 X 2369 . T <*> 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 X 2370 . G <*> 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 X 2371 . G <*> 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 X 2372 . C <*> 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 X 2373 . C <*> 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 X 2374 . A <*> 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 X 2375 . A <*> 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 X 2376 . T <*> 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 X 2377 . A <*> 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 X 2378 . C <*> 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 X 2379 . G <*> 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 X 2380 . G <*> 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 X 2381 . C <*> 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 X 2382 . A <*> 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 X 2383 . A <*> 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 X 2384 . A <*> 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 X 2385 . A <*> 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 X 2386 . C <*> 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 X 2387 . C <*> 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 X 2388 . C <*> 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 X 2389 . A <*> 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 X 2390 . G <*> 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 X 2391 . T <*> 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 X 2392 . C <*> 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 X 2393 . T <*> 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 X 2394 . C <*> 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 X 2395 . T <*> 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 X 2396 . A <*> 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 X 2397 . C <*> 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 X 2398 . A <*> 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 X 2399 . A <*> 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 X 2400 . A <*> 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 X 2401 . A <*> 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 X 2402 . A <*> 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 X 2403 . A <*> 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 X 2404 . T <*> 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 X 2405 . A <*> 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 X 2406 . C <*> 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 X 2407 . A <*> 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 X 2408 . A <*> 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 X 2409 . A <*> 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 X 2410 . A <*> 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 X 2411 . A <*> 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 X 2412 . A <*> 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 X 2413 . C <*> 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 X 2414 . A <*> 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 X 2415 . A <*> 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 X 2416 . C <*> 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 X 2417 . T <*> 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 X 2418 . A <*> 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 X 2419 . G <*> 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 X 2420 . C <*> 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 X 2421 . C <*> 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 X 2422 . A <*> 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 X 2423 . G <*> 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 X 2424 . G <*> 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 X 2425 . C <*> 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 X 2426 . G <*> 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 X 2427 . T <*> 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 X 2428 . G <*> 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 X 2429 . G <*> 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 X 2430 . T A,<*> 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 X 2431 . G <*> 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 X 2432 . G <*> 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 X 2433 . T <*> 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 X 2434 . G <*> 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 X 2435 . C <*> 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 X 2436 . A <*> 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 X 2437 . C <*> 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 X 2438 . A <*> 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 X 2439 . C <*> 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 X 2440 . C <*> 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 X 2441 . T <*> 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 X 2442 . G <*> 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 X 2443 . T <*> 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 X 2444 . A <*> 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 X 2445 . G <*> 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 X 2446 . T <*> 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 X 2447 . C <*> 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 X 2448 . C <*> 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 X 2449 . C <*> 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 X 2450 . A <*> 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 X 2451 . G <*> 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 X 2452 . C <*> 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 X 2453 . T <*> 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 X 2454 . A <*> 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 X 2455 . C <*> 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 X 2456 . T <*> 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 X 2457 . C <*> 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 X 2458 . A <*> 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 X 2459 . G T,<*> 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 X 2460 . G <*> 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 X 2461 . A G,<*> 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 X 2462 . G <*> 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 X 2463 . G T,<*> 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 X 2464 . C <*> 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 X 2465 . T <*> 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 X 2466 . G <*> 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 X 2467 . A <*> 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 X 2468 . G <*> 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 X 2469 . G <*> 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 X 2470 . G <*> 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 X 2471 . G <*> 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 X 2472 . G <*> 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 X 2473 . A <*> 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 X 2474 . A <*> 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 X 2475 . G <*> 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 X 2476 . G <*> 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 X 2477 . A <*> 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 X 2478 . C <*> 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 X 2479 . T <*> 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 X 2480 . G <*> 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 X 2481 . C <*> 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 X 2482 . T <*> 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 X 2483 . T <*> 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 X 2484 . G <*> 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 X 2485 . A T,<*> 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 X 2486 . G <*> 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 X 2487 . C <*> 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 X 2488 . C <*> 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 X 2489 . C <*> 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 X 2490 . A <*> 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 X 2491 . G <*> 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 X 2492 . G A,<*> 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 X 2493 . A G,<*> 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 X 2494 . G <*> 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 X 2495 . T <*> 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 X 2496 . T <*> 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 X 2497 . T <*> 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 X 2498 . G <*> 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 X 2499 . A <*> 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 X 2500 . G <*> 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 X 2501 . G <*> 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 X 2502 . C <*> 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 X 2503 . T <*> 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 X 2504 . G <*> 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 X 2505 . C <*> 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 X 2506 . T <*> 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 X 2507 . G <*> 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 X 2508 . T <*> 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 X 2509 . G T,<*> 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 X 2510 . A <*> 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 X 2511 . G <*> 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 X 2512 . C <*> 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 X 2513 . T <*> 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 X 2514 . G <*> 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 X 2515 . T <*> 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 X 2516 . G <*> 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 X 2517 . A <*> 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 X 2518 . T <*> 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 X 2519 . C <*> 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 X 2520 . G <*> 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 X 2521 . C <*> 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 X 2522 . A <*> 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 X 2523 . T <*> 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 X 2524 . C <*> 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 X 2525 . A C,<*> 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 X 2526 . C <*> 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 X 2527 . T <*> 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 X 2528 . G <*> 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 X 2529 . C <*> 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 X 2530 . A <*> 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 X 2531 . T <*> 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 X 2532 . T <*> 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 X 2533 . C <*> 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 X 2534 . C <*> 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 X 2535 . A <*> 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 X 2536 . G <*> 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 X 2537 . C <*> 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 X 2538 . C <*> 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 X 2539 . C <*> 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 X 2540 . G <*> 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 X 2541 . G <*> 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 X 2542 . T <*> 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 X 2543 . G <*> 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 X 2544 . A <*> 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 X 2545 . C <*> 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 X 2546 . A <*> 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 X 2547 . G <*> 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 X 2548 . A <*> 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 X 2549 . G <*> 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 X 2550 . T <*> 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 X 2551 . G <*> 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 X 2552 . A <*> 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 X 2553 . G <*> 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 X 2554 . T <*> 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 X 2555 . C <*> 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 X 2556 . A <*> 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 X 2557 . C <*> 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 X 2558 . T <*> 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 X 2559 . G <*> 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 X 2560 . T <*> 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 X 2561 . C <*> 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 X 2562 . T <*> 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 X 2563 . C <*> 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 X 2564 . A G,<*> 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 X 2565 . A <*> 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 X 2566 . A <*> 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 X 2567 . A <*> 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 X 2568 . A <*> 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 X 2569 . A <*> 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 X 2570 . G <*> 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 X 2571 . A <*> 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 X 2572 . A <*> 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 X 2573 . A <*> 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 X 2574 . G <*> 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 X 2575 . G <*> 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 X 2576 . A <*> 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 X 2577 . A <*> 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 X 2578 . G <*> 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 X 2579 . A <*> 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 X 2580 . A <*> 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 X 2581 . A <*> 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 X 2582 . T <*> 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 X 2583 . A <*> 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 X 2584 . A <*> 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 X 2585 . A <*> 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 X 2586 . G <*> 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 X 2587 . A <*> 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 X 2588 . A <*> 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 X 2589 . A <*> 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 X 2590 . A <*> 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 X 2591 . C <*> 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 X 2592 . A <*> 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 X 2593 . A <*> 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 X 2594 . A <*> 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 X 2595 . T <*> 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 X 2596 . A <*> 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 X 2597 . A <*> 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 X 2598 . A <*> 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 X 2599 . A <*> 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 X 2600 . A <*> 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 X 2601 . T <*> 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 X 2602 . A <*> 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 X 2603 . A <*> 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 X 2604 . T <*> 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 X 2605 . A <*> 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 X 2606 . G <*> 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 X 2607 . T <*> 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 X 2608 . G <*> 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 X 2609 . C <*> 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 X 2610 . A <*> 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 X 2611 . G <*> 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 X 2612 . A <*> 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 X 2613 . C <*> 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 X 2614 . A <*> 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 X 2615 . A <*> 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 X 2616 . A <*> 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 X 2617 . A <*> 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 X 2618 . G <*> 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 X 2619 . G <*> 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 X 2620 . C <*> 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 X 2621 . C <*> 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 X 2622 . T <*> 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 X 2623 . T <*> 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 X 2624 . G <*> 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 X 2625 . A <*> 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 X 2626 . C <*> 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 X 2627 . C <*> 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 X 2628 . C <*> 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 X 2629 . A <*> 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 X 2630 . T <*> 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 X 2631 . C <*> 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 X 2632 . T <*> 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 X 2633 . A <*> 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 X 2634 . G <*> 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 X 2635 . C <*> 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 X 2636 . T <*> 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 X 2637 . T <*> 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 X 2638 . T <*> 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 X 2639 . G <*> 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 X 2640 . G <*> 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 X 2641 . C <*> 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 X 2642 . C <*> 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 X 2643 . C <*> 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 X 2644 . T <*> 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 X 2645 . C <*> 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 X 2646 . A <*> 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 X 2647 . G <*> 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 X 2648 . C <*> 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 X 2649 . A <*> 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 X 2650 . T <*> 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 X 2651 . C <*> 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 X 2652 . A <*> 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 X 2653 . A <*> 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 X 2654 . C <*> 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 X 2655 . C <*> 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 X 2656 . G <*> 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 X 2657 . C <*> 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 X 2658 . T <*> 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 X 2659 . A <*> 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 X 2660 . G <*> 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 X 2661 . A <*> 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 X 2662 . T <*> 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 X 2663 . A <*> 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 X 2664 . C <*> 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 X 2665 . G <*> 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 X 2666 . T <*> 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 X 2667 . C <*> 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 X 2668 . C <*> 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 X 2669 . C <*> 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 X 2670 . T <*> 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 X 2671 . C <*> 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 X 2672 . C <*> 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 X 2673 . C <*> 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 X 2674 . T <*> 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 X 2675 . T <*> 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 X 2676 . T <*> 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 X 2677 . C <*> 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 X 2678 . T <*> 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 X 2679 . T <*> 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 X 2680 . C <*> 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 X 2681 . T <*> 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 X 2682 . G <*> 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 X 2683 . G <*> 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 X 2684 . G <*> 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 X 2685 . G <*> 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 X 2686 . C <*> 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 X 2687 . A <*> 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 X 2688 . C <*> 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 X 2689 . A <*> 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 X 2690 . G <*> 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 X 2691 . G <*> 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 X 2692 . T <*> 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 X 2693 . C <*> 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 X 2694 . A <*> 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 X 2695 . C <*> 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 X 2696 . A <*> 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 X 2697 . C <*> 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 X 2698 . T <*> 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 X 2699 . C <*> 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 X 2700 . T <*> 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 X 2701 . C <*> 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 X 2702 . T <*> 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 X 2703 . T <*> 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 X 2704 . C <*> 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 X 2705 . C <*> 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 X 2706 . A <*> 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 X 2707 . G <*> 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 X 2708 . G <*> 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 X 2709 . T <*> 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 X 2710 . C <*> 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 X 2711 . T <*> 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 X 2712 . A <*> 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 X 2713 . G T,<*> 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 X 2714 . G <*> 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 X 2715 . A <*> 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 X 2716 . T <*> 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 X 2717 . G <*> 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 X 2718 . C <*> 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 X 2719 . A <*> 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 X 2720 . G <*> 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 X 2721 . C <*> 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 X 2722 . T <*> 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 X 2723 . G <*> 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 X 2724 . A <*> 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 X 2725 . G <*> 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 X 2726 . G <*> 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 X 2727 . G <*> 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 X 2728 . G <*> 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 X 2729 . T <*> 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 X 2730 . G <*> 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 X 2731 . C <*> 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 X 2732 . C <*> 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 X 2733 . C A,<*> 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 X 2734 . C <*> 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 X 2735 . T <*> 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 X 2736 . C <*> 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 X 2737 . T <*> 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 X 2738 . T <*> 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 X 2739 . A <*> 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 X 2740 . C <*> 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 X 2741 . C <*> 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 X 2742 . A <*> 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 X 2743 . T <*> 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 X 2744 . C <*> 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 X 2745 . T <*> 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 X 2746 . A <*> 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 X 2747 . A <*> 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 X 2748 . T <*> 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 X 2749 . C <*> 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 X 2750 . T <*> 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 X 2751 . G <*> 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 X 2752 . T <*> 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 X 2753 . G <*> 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 X 2754 . C <*> 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 X 2755 . C <*> 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 X 2756 . C <*> 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 X 2757 . T <*> 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 X 2758 . T <*> 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 X 2759 . A <*> 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 X 2760 . T <*> 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 X 2761 . T <*> 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 X 2762 . T <*> 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 X 2763 . C A,<*> 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 X 2764 . C <*> 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 X 2765 . T <*> 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 X 2766 . C <*> 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 X 2767 . T <*> 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 X 2768 . G <*> 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 X 2769 . C <*> 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 X 2770 . T <*> 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 X 2771 . T <*> 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 X 2772 . T <*> 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 X 2773 . A <*> 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 X 2774 . G <*> 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 X 2775 . T <*> 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 X 2776 . G <*> 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 X 2777 . A <*> 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 X 2778 . G <*> 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 X 2779 . G <*> 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 X 2780 . A <*> 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 X 2781 . A <*> 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 X 2782 . G <*> 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 X 2783 . A <*> 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 X 2784 . G <*> 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 X 2785 . G <*> 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 X 2786 . C <*> 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 X 2787 . C <*> 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 X 2788 . C <*> 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 X 2789 . C <*> 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 X 2790 . T <*> 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 X 2791 . G <*> 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 X 2792 . G <*> 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 X 2793 . T <*> 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 X 2794 . C <*> 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 X 2795 . C <*> 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 X 2796 . A <*> 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 X 2797 . T <*> 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 X 2798 . G <*> 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 X 2799 . A <*> 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 X 2800 . A <*> 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 X 2801 . G <*> 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 X 2802 . G <*> 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 X 2803 . G <*> 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 X 2804 . G <*> 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 X 2805 . C <*> 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 X 2806 . C <*> 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 X 2807 . T <*> 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 X 2808 . T <*> 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 X 2809 . T <*> 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 X 2810 . C <*> 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 X 2811 . A <*> 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 X 2812 . G <*> 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 X 2813 . A <*> 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 X 2814 . G <*> 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 X 2815 . A <*> 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 X 2816 . C <*> 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 X 2817 . G <*> 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 X 2818 . G <*> 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 X 2819 . G <*> 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 X 2820 . G <*> 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 X 2821 . A <*> 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 X 2822 . C <*> 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 X 2823 . C <*> 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 X 2824 . C <*> 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 X 2825 . C <*> 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 X 2826 . T <*> 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 X 2827 . G <*> 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 X 2828 . A <*> 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 X 2829 . G <*> 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 X 2830 . G <*> 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 X 2831 . A <*> 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 X 2832 . G <*> 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 X 2833 . C <*> 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 X 2834 . C <*> 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 X 2835 . C <*> 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 X 2836 . C <*> 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 X 2837 . G <*> 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 X 2838 . A <*> 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 X 2839 . G <*> 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 X 2840 . C <*> 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 X 2841 . A <*> 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 X 2842 . G <*> 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 X 2843 . C <*> 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 X 2844 . A <*> 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 X 2845 . G <*> 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 X 2846 . C <*> 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 X 2847 . C <*> 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 X 2848 . G <*> 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 X 2849 . T <*> 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 X 2850 . C <*> 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 X 2851 . G <*> 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 X 2852 . T <*> 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 X 2853 . G <*> 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 X 2854 . T <*> 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 X 2855 . C <*> 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 X 2856 . T <*> 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 X 2857 . C <*> 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 X 2858 . A <*> 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 X 2859 . C <*> 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 X 2860 . C <*> 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 X 2861 . C <*> 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 X 2862 . A <*> 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 X 2863 . G <*> 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 X 2864 . G <*> 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 X 2865 . G <*> 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 X 2866 . T <*> 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 X 2867 . G <*> 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 X 2868 . T <*> 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 X 2869 . C <*> 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 X 2870 . T <*> 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 X 2871 . G <*> 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 X 2872 . A <*> 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 X 2873 . A <*> 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 X 2874 . A <*> 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 X 2875 . C <*> 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 X 2876 . A <*> 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 X 2877 . G <*> 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 X 2878 . A <*> 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 X 2879 . T <*> 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 X 2880 . G <*> 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 X 2881 . T <*> 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 X 2882 . G <*> 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 X 2883 . G <*> 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 X 2884 . A <*> 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 X 2885 . G <*> 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 X 2886 . G A,<*> 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 X 2887 . T <*> 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 X 2888 . C <*> 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 X 2889 . T <*> 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 X 2890 . C <*> 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 X 2891 . G <*> 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 X 2892 . G <*> 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 X 2893 . G <*> 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 X 2894 . T <*> 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 X 2895 . G <*> 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 X 2896 . A <*> 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 X 2897 . G <*> 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 X 2898 . G <*> 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 X 2899 . C <*> 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 X 2900 . G <*> 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 X 2901 . T <*> 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 X 2902 . G <*> 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 X 2903 . G <*> 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 X 2904 . C <*> 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 X 2905 . T <*> 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 X 2906 . C <*> 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 X 2907 . A <*> 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 X 2908 . G <*> 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 X 2909 . A <*> 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 X 2910 . T <*> 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 X 2911 . A <*> 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 X 2912 . C <*> 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 X 2913 . A <*> 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 X 2914 . G <*> 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 X 2915 . G <*> 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 X 2916 . G <*> 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 X 2917 . A <*> 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 X 2918 . G <*> 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 X 2919 . T <*> 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 X 2920 . G <*> 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 X 2921 . G <*> 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 X 2922 . C <*> 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 X 2923 . C <*> 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 X 2924 . C <*> 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 X 2925 . A <*> 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 X 2926 . C <*> 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 X 2927 . A <*> 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 X 2928 . G <*> 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 X 2929 . C <*> 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 X 2930 . T <*> 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 X 2931 . C <*> 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 X 2932 . G <*> 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 X 2933 . G <*> 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 X 2934 . C <*> 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 X 2935 . C <*> 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 X 2936 . T <*> 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 X 2937 . G <*> 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 X 2938 . T <*> 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 X 2939 . C <*> 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 X 2940 . T <*> 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 X 2941 . T <*> 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 X 2942 . T <*> 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 X 2943 . G <*> 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 X 2944 . A <*> 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 X 2945 . A <*> 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 X 2946 . A <*> 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 X 2947 . G <*> 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 X 2948 . G <*> 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 X 2949 . C <*> 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 X 2950 . C <*> 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 X 2951 . A <*> 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 X 2952 . C <*> 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 X 2953 . G <*> 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 X 2954 . T <*> 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 X 2955 . G <*> 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 X 2956 . A <*> 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 X 2957 . C <*> 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 X 2958 . C <*> 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 X 2959 . T <*> 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 X 2960 . G <*> 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 X 2961 . G <*> 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 X 2962 . C <*> 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 X 2963 . C <*> 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 X 2964 . C <*> 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 X 2965 . A <*> 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 X 2966 . C <*> 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 X 2967 . G <*> 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 X 2968 . G <*> 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 X 2969 . C <*> 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 X 2970 . T <*> 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 X 2971 . G <*> 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 X 2972 . G <*> 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 X 2973 . C <*> 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 X 2974 . A <*> 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 X 2975 . G <*> 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 X 2976 . G <*> 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 X 2977 . T <*> 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 X 2978 . G <*> 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 X 2979 . G <*> 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 X 2980 . G <*> 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 X 2981 . A <*> 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 X 2982 . C <*> 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 X 2983 . C <*> 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 X 2984 . C <*> 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 X 2985 . A <*> 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 X 2986 . G <*> 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 X 2987 . C <*> 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 X 2988 . T <*> 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 X 2989 . G <*> 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 X 2990 . C <*> 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 X 2991 . A <*> 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 X 2992 . G <*> 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 X 2993 . G <*> 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 X 2994 . G <*> 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 X 2995 . G <*> 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 X 2996 . T <*> 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 X 2997 . C <*> 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 X 2998 . C <*> 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 X 2999 . A <*> 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 X 3000 . G <*> 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 X 3001 . C <*> 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 X 3002 . A <*> 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 X 3003 . G <*> 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 X 3004 . C <*> 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 X 3005 . A <*> 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 X 3006 . C <*> 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 X 3007 . C <*> 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 X 3008 . C <*> 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 X 3009 . A <*> 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 X 3010 . C <*> 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 X 3011 . A <*> 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 X 3012 . G <*> 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 X 3013 . C <*> 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 X 3014 . A <*> 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 X 3015 . G <*> 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 X 3016 . C <*> 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 X 3017 . C A,<*> 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 X 3018 . A <*> 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 X 3019 . C <*> 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 X 3020 . C <*> 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 X 3021 . T <*> 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 X 3022 . G <*> 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 X 3023 . T G,<*> 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 X 3024 . G <*> 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 X 3025 . G <*> 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 X 3026 . C <*> 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 X 3027 . A <*> 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 X 3028 . G <*> 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 X 3029 . G <*> 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 X 3030 . G <*> 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 X 3031 . A <*> 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 X 3032 . G <*> 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 X 3033 . G <*> 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 X 3034 . A <*> 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 X 3035 . G <*> 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 X 3036 . C <*> 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 X 3037 . T <*> 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 X 3038 . T <*> 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 X 3039 . G <*> 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 X 3040 . T <*> 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 X 3041 . G <*> 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 X 3042 . G <*> 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 X 3043 . T <*> 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 X 3044 . A C,<*> 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 X 3045 . C <*> 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 X 3046 . A <*> 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 X 3047 . G <*> 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 X 3048 . T <*> 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 X 3049 . G <*> 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 X 3050 . G <*> 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 X 3051 . A <*> 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 X 3052 . C <*> 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 X 3053 . A <*> 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 X 3054 . G <*> 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 X 3055 . G <*> 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 X 3056 . C <*> 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 X 3057 . C <*> 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 X 3058 . C <*> 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 X 3059 . T G,<*> 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 X 3060 . G <*> 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 X 3061 . C <*> 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 X 3062 . C <*> 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 X 3063 . C <*> 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 X 3064 . A <*> 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 X 3065 . G <*> 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 X 3066 . A <*> 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 X 3067 . T <*> 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 X 3068 . G <*> 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 X 3069 . G <*> 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 X 3070 . C <*> 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 X 3071 . C <*> 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 X 3072 . C <*> 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 X 3073 . C <*> 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 X 3074 . C <*> 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 X 3075 . C <*> 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 X 3076 . G <*> 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 X 3077 . C <*> 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 X 3078 . C <*> 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 X 3079 . T <*> 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 X 3080 . G <*> 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 X 3081 . C <*> 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 X 3082 . C <*> 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 X 3083 . T C,<*> 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 X 3084 . G <*> 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 X 3085 . T <*> 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 X 3086 . G <*> 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 X 3087 . G <*> 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 X 3088 . A <*> 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 X 3089 . A <*> 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 X 3090 . G <*> 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 X 3091 . T <*> 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 X 3092 . T <*> 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 X 3093 . G <*> 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 X 3094 . A <*> 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 X 3095 . C <*> 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 X 3096 . C <*> 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 X 3097 . A <*> 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 X 3098 . G <*> 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 X 3099 . A <*> 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 X 3100 . C <*> 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 X 3101 . C <*> 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 X 3102 . A <*> 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 X 3103 . T <*> 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 X 3104 . C T,<*> 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 X 3105 . T <*> 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 X 3106 . G <*> 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 X 3107 . T <*> 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 X 3108 . C <*> 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 X 3109 . A <*> 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 X 3110 . C <*> 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 X 3111 . A <*> 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 X 3112 . G <*> 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 X 3113 . C <*> 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 X 3114 . A <*> 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 X 3115 . G <*> 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 X 3116 . G <*> 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 X 3117 . T <*> 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 X 3118 . A <*> 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 X 3119 . A <*> 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 X 3120 . G <*> 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 X 3121 . A <*> 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 X 3122 . C <*> 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 X 3123 . T <*> 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 X 3124 . C <*> 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 X 3125 . T <*> 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 X 3126 . G <*> 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 X 3127 . C <*> 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 X 3128 . T <*> 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 X 3129 . T <*> 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 X 3130 . T <*> 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 X 3131 . C <*> 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 X 3132 . T <*> 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 X 3133 . G <*> 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 X 3134 . G <*> 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 X 3135 . G <*> 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 X 3136 . C <*> 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 X 3137 . A <*> 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 X 3138 . A <*> 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 X 3139 . C <*> 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 X 3140 . C <*> 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 X 3141 . C <*> 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 X 3142 . A <*> 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 X 3143 . G <*> 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 X 3144 . C <*> 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 X 3145 . A <*> 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 X 3146 . G <*> 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 X 3147 . G <*> 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 X 3148 . T <*> 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 X 3149 . G <*> 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 X 3150 . A <*> 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 X 3151 . C <*> 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 X 3152 . C <*> 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 X 3153 . C <*> 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 X 3154 . T <*> 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 X 3155 . G <*> 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 X 3156 . G <*> 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 X 3157 . A <*> 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 X 3158 . A <*> 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 X 3159 . T <*> 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 X 3160 . T <*> 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 X 3161 . C <*> 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 X 3162 . C <*> 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 X 3163 . T A,<*> 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 X 3164 . G <*> 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 X 3165 . T <*> 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 X 3166 . C <*> 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 X 3167 . C <*> 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 X 3168 . A <*> 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 X 3169 . T <*> 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 X 3170 . C <*> 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 X 3171 . T <*> 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 X 3172 . G <*> 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 X 3173 . G <*> 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 X 3174 . C <*> 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 X 3175 . A <*> 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 X 3176 . G <*> 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 X 3177 . G <*> 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 X 3178 . T <*> 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 X 3179 . G <*> 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 X 3180 . G <*> 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 X 3181 . G <*> 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 X 3182 . C <*> 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 X 3183 . A <*> 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 X 3184 . T <*> 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 X 3185 . T <*> 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 X 3186 . G <*> 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 X 3187 . A <*> 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 X 3188 . A <*> 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 X 3189 . A <*> 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 X 3190 . C <*> 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 X 3191 . T <*> 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 X 3192 . G <*> 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 X 3193 . G <*> 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 X 3194 . T C,<*> 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 X 3195 . T <*> 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 X 3196 . T <*> 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 X 3197 . A <*> 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 X 3198 . A <*> 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 X 3199 . A <*> 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 X 3200 . A <*> 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 X 3201 . A <*> 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 X 3202 . T <*> 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 X 3203 . G A,<*> 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 X 3204 . T <*> 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 X 3205 . C <*> 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 X 3206 . A <*> 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 X 3207 . C <*> 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 X 3208 . A <*> 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 X 3209 . C <*> 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 X 3210 . C <*> 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 X 3211 . A <*> 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 X 3212 . T <*> 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 X 3213 . A <*> 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 X 3214 . G <*> 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 X 3215 . G <*> 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 X 3216 . C <*> 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 X 3217 . C <*> 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 X 3218 . G C,<*> 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 X 3219 . G A,<*> 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 X 3220 . G <*> 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 X 3221 . C <*> 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 X 3222 . A <*> 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 X 3223 . C <*> 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 X 3224 . A <*> 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 X 3225 . G <*> 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 X 3226 . T <*> 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 X 3227 . G <*> 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 X 3228 . G <*> 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 X 3229 . C <*> 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 X 3230 . T <*> 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 X 3231 . C <*> 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 X 3232 . A <*> 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 X 3233 . C <*> 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 X 3234 . G T,<*> 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 X 3235 . C <*> 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 X 3236 . C <*> 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 X 3237 . T <*> 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 X 3238 . G <*> 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 X 3239 . T <*> 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 X 3240 . A <*> 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 X 3241 . A <*> 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 X 3242 . T <*> 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 X 3243 . C <*> 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 X 3244 . C <*> 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 X 3245 . C <*> 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 X 3246 . A <*> 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 X 3247 . G <*> 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 X 3248 . C <*> 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 X 3249 . C <*> 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 X 3250 . C <*> 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 X 3251 . T <*> 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 X 3252 . T <*> 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 X 3253 . T <*> 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 X 3254 . G <*> 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 X 3255 . G <*> 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 X 3256 . G <*> 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 X 3257 . A <*> 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 X 3258 . G <*> 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 X 3259 . G <*> 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 X 3260 . C <*> 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 X 3261 . C <*> 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 X 3262 . A <*> 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 X 3263 . G <*> 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 X 3264 . G <*> 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 X 3265 . G <*> 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 X 3266 . T <*> 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 X 3267 . G <*> 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 X 3268 . G <*> 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 X 3269 . G <*> 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 X 3270 . T <*> 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 X 3271 . G <*> 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 X 3272 . G <*> 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 X 3273 . A <*> 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 X 3274 . T <*> 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 X 3275 . C <*> 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 X 3276 . A <*> 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 X 3277 . C <*> 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 X 3278 . T <*> 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 X 3279 . T <*> 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 X 3280 . G <*> 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 X 3281 . A <*> 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 X 3282 . G <*> 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 X 3283 . G <*> 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 X 3284 . T <*> 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 X 3285 . C <*> 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 X 3286 . A <*> 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 X 3287 . G <*> 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 X 3288 . G <*> 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 X 3289 . A <*> 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 X 3290 . G <*> 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 X 3291 . T <*> 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 X 3292 . T <*> 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 X 3293 . C <*> 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 X 3294 . A <*> 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 X 3295 . A <*> 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 X 3296 . G <*> 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 X 3297 . A <*> 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 X 3298 . C <*> 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 X 3299 . C <*> 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 X 3300 . A <*> 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 X 3301 . G <*> 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 X 3302 . C <*> 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 X 3303 . C <*> 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 X 3304 . T <*> 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 X 3305 . G <*> 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 X 3306 . G <*> 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 X 3307 . C <*> 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 X 3308 . C <*> 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 X 3309 . A <*> 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 X 3310 . A <*> 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 X 3311 . C <*> 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 X 3312 . A <*> 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 X 3313 . T <*> 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 X 3314 . G <*> 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 X 3315 . G <*> 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 X 3316 . T <*> 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 X 3317 . G <*> 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 X 3318 . A <*> 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 X 3319 . A <*> 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 X 3320 . A <*> 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 X 3321 . C <*> 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 X 3322 . C <*> 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 X 3323 . C <*> 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 X 3324 . C <*> 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 X 3325 . G <*> 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 X 3326 . T <*> 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 X 3327 . C <*> 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 X 3328 . T <*> 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 X 3329 . A <*> 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 X 3330 . C <*> 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 X 3331 . T <*> 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 X 3332 . A <*> 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 X 3333 . A <*> 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 X 3334 . A <*> 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 X 3335 . A <*> 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 X 3336 . A <*> 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 X 3337 . T <*> 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 X 3338 . A <*> 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 X 3339 . C <*> 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 X 3340 . A <*> 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 X 3341 . A <*> 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 X 3342 . A <*> 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 X 3343 . A <*> 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 X 3344 . A <*> 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 X 3345 . T <*> 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 X 3346 . T <*> 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 X 3347 . A <*> 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 X 3348 . G <*> 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 X 3349 . C <*> 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 X 3350 . C <*> 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 X 3351 . T <*> 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 X 3352 . G <*> 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 X 3353 . G <*> 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 X 3354 . C <*> 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 X 3355 . G <*> 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 X 3356 . T <*> 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 X 3357 . G <*> 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 X 3358 . G <*> 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 X 3359 . T <*> 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 X 3360 . G <*> 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 X 3361 . G <*> 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 X 3362 . C <*> 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 X 3363 . G <*> 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 X 3364 . C <*> 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 X 3365 . A <*> 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 X 3366 . T <*> 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 X 3367 . G <*> 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 X 3368 . C <*> 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 X 3369 . C <*> 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 X 3370 . T <*> 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 X 3371 . G <*> 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 X 3372 . T <*> 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 X 3373 . A <*> 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 X 3374 . A <*> 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 X 3375 . T <*> 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 X 3376 . C <*> 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 X 3377 . C <*> 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 X 3378 . C <*> 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 X 3379 . A <*> 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 X 3380 . G <*> 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 X 3381 . C <*> 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 X 3382 . T <*> 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 X 3383 . A <*> 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 X 3384 . C <*> 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 X 3385 . T <*> 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 X 3386 . T <*> 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 X 3387 . G <*> 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 X 3388 . G <*> 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 X 3389 . G <*> 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 X 3390 . A <*> 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 X 3391 . A <*> 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 X 3392 . G <*> 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 X 3393 . C <*> 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 X 3394 . T <*> 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 X 3395 . G <*> 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 X 3396 . A <*> 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 X 3397 . G <*> 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 X 3398 . G <*> 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 X 3399 . G <*> 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 X 3400 . A <*> 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 X 3401 . T <*> 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 X 3402 . G <*> 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 X 3403 . A <*> 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 X 3404 . G <*> 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 X 3405 . A <*> 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 X 3406 . A <*> 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 X 3407 . C <*> 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 X 3408 . T <*> 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 X 3409 . G <*> 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 X 3410 . C <*> 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 X 3411 . T <*> 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 X 3412 . T <*> 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 X 3413 . G <*> 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 X 3414 . A <*> 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 X 3415 . A <*> 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 X 3416 . C <*> 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 X 3417 . C <*> 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 X 3418 . T <*> 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 X 3419 . G <*> 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 X 3420 . G <*> 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 X 3421 . G <*> 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 X 3422 . A <*> 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 X 3423 . G <*> 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 X 3424 . G <*> 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 X 3425 . C <*> 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 X 3426 . A <*> 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 X 3427 . G <*> 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 X 3428 . A <*> 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 X 3429 . C <*> 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 X 3430 . G <*> 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 X 3431 . T <*> 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 X 3432 . T <*> 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 X 3433 . G <*> 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 X 3434 . C <*> 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 X 3435 . A <*> 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 X 3436 . G <*> 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 X 3437 . T G,<*> 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 X 3438 . G <*> 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 X 3439 . A <*> 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 X 3440 . G <*> 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 X 3441 . C <*> 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 X 3442 . T <*> 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 X 3443 . G <*> 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 X 3444 . A <*> 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 X 3445 . G <*> 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 X 3446 . A <*> 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 X 3447 . T <*> 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 X 3448 . C <*> 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 X 3449 . A <*> 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 X 3450 . C <*> 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 X 3451 . G <*> 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 X 3452 . C <*> 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 X 3453 . C <*> 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 X 3454 . A <*> 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 X 3455 . C <*> 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 X 3456 . T <*> 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 X 3457 . G <*> 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 X 3458 . C <*> 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 X 3459 . A C,<*> 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 X 3460 . C <*> 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 X 3461 . T <*> 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 X 3462 . C <*> 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 X 3463 . C <*> 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 X 3464 . A <*> 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 X 3465 . G <*> 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 X 3466 . C <*> 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 X 3467 . C <*> 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 X 3468 . T <*> 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 X 3469 . G <*> 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 X 3470 . G <*> 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 X 3471 . G <*> 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 X 3472 . C <*> 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 X 3473 . A <*> 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 X 3474 . A <*> 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 X 3475 . C <*> 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 X 3476 . A <*> 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 X 3477 . G <*> 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 X 3478 . A <*> 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 X 3479 . G <*> 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 X 3480 . T <*> 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 X 3481 . A <*> 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 X 3482 . A <*> 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 X 3483 . G <*> 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 X 3484 . A C,<*> 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 X 3485 . C <*> 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 X 3486 . T <*> 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 X 3487 . C <*> 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 X 3488 . T <*> 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 X 3489 . G <*> 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 X 3490 . T C,<*> 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 X 3491 . C <*> 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 X 3492 . T <*> 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 X 3493 . C <*> 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 X 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 X 3494 . A <*> 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 X 3495 . A <*> 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 X 3496 . A <*> 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 X 3497 . A <*> 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 X 3498 . A <*> 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 X 3499 . A <*> 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 X 3500 . A <*> 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 X 3501 . A <*> 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 X 3502 . A <*> 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 X 3503 . A <*> 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 X 3504 . A <*> 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 X 3505 . A <*> 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 X 3506 . A <*> 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 X 3507 . T <*> 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 X 3508 . C <*> 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 X 3509 . A <*> 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 X 3510 . C A,<*> 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 X 3511 . A <*> 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 X 3512 . C <*> 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 X 3513 . C A,<*> 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 X 3514 . A <*> 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 X 3515 . T <*> 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 X 3516 . T <*> 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 X 3517 . T <*> 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 X 3518 . T <*> 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 X 3519 . G <*> 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 X 3520 . G <*> 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 X 3521 . C <*> 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 X 3522 . T <*> 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 X 3523 . T <*> 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 X 3524 . C <*> 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 X 3525 . A <*> 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 X 3526 . G <*> 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 X 3527 . A <*> 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 X 3528 . T <*> 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 X 3529 . T <*> 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 X 3530 . G <*> 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 X 3531 . C A,<*> 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 X 3532 . A <*> 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 X 3533 . T <*> 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 X 3534 . A <*> 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 X 3535 . T <*> 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 X 3536 . C <*> 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 X 3537 . C <*> 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 X 3538 . T <*> 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 X 3539 . C <*> 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 X 3540 . C <*> 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 X 3541 . T <*> 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 X 3542 . G <*> 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 X 3543 . C <*> 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 X 3544 . A <*> 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 X 3545 . A <*> 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 X 3546 . G <*> 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 X 3547 . G <*> 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 X 3548 . A <*> 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 X 3549 . T <*> 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 X 3550 . A <*> 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 X 3551 . T <*> 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 X 3552 . A <*> 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 X 3553 . T A,<*> 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 X 3554 . A <*> 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 X 3555 . C <*> 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 X 3556 . G <*> 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 X 3557 . C <*> 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 X 3558 . G <*> 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 X 3559 . T <*> 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 X 3560 . G <*> 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 X 3561 . A <*> 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 X 3562 . A <*> 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 X 3563 . A <*> 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 X 3564 . T <*> 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 X 3565 . T <*> 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 X 3566 . C <*> 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 X 3567 . A <*> 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 X 3568 . A <*> 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 X 3569 . G <*> 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 X 3570 . T <*> 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 X 3571 . C <*> 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 X 3572 . A <*> 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 X 3573 . A <*> 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 X 3574 . T <*> 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 X 3575 . G <*> 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 X 3576 . A <*> 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 X 3577 . C <*> 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 X 3578 . A <*> 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 X 3579 . A <*> 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 X 3580 . A <*> 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 X 3581 . T <*> 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 X 3582 . C <*> 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 X 3583 . A <*> 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 X 3584 . G <*> 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 X 3585 . A <*> 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 X 3586 . A <*> 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 X 3587 . G A,<*> 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 X 3588 . A <*> 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 X 3589 . A <*> 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 X 3590 . A <*> 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 X 3591 . A <*> 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 X 3592 . A <*> 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 X 3593 . A <*> 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 X 3594 . C <*> 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 X 3595 . A <*> 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 X 3596 . T <*> 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 X 3597 . A <*> 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 X 3598 . T <*> 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 X 3599 . A <*> 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 X 3600 . T <*> 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 X 3601 . A <*> 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 X 3602 . T <*> 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 X 3603 . A <*> 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 X 3604 . C <*> 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 X 3605 . G <*> 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 X 3606 . C <*> 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 X 3607 . A <*> 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 X 3608 . A <*> 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 X 3609 . A <*> 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 X 3610 . C <*> 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 X 3611 . C <*> 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 X 3612 . A <*> 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 X 3613 . G <*> 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 X 3614 . T <*> 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 X 3615 . A <*> 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 X 3616 . T <*> 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 X 3617 . C <*> 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 X 3618 . C <*> 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 X 3619 . T <*> 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 X 3620 . A <*> 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 X 3621 . C <*> 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 X 3622 . T <*> 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 X 3623 . G <*> 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 X 3624 . T <*> 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 X 3625 . G <*> 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 X 3626 . T <*> 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 X 3627 . G <*> 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 X 3628 . T <*> 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 X 3629 . G <*> 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 X 3630 . T <*> 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 X 3631 . C <*> 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 X 3632 . G <*> 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 X 3633 . T <*> 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 X 3634 . T <*> 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 X 3635 . T <*> 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 X 3636 . G <*> 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 X 3637 . T <*> 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 X 3638 . T <*> 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 X 3639 . G <*> 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 X 3640 . T <*> 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 X 3641 . G <*> 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 X 3642 . T <*> 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 X 3643 . T <*> 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 X 3644 . T <*> 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 X 3645 . T <*> 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 X 3646 . C <*> 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 X 3647 . G <*> 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 X 3648 . A <*> 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 X 3649 . C <*> 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 X 3650 . A <*> 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 X 3651 . G <*> 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 X 3652 . C <*> 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 X 3653 . T <*> 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 X 3654 . G <*> 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 X 3655 . T <*> 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 X 3656 . C <*> 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 X 3657 . C <*> 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 X 3658 . G <*> 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 X 3659 . T <*> 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 X 3660 . G <*> 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 X 3661 . T <*> 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 X 3662 . T <*> 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 X 3663 . A <*> 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 X 3664 . T <*> 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 X 3665 . A <*> 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 X 3666 . A <*> 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 X 3667 . T <*> 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 X 3668 . A <*> 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 X 3669 . A <*> 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 X 3670 . T <*> 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 X 3671 . T <*> 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 X 3672 . C <*> 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 X 3673 . C <*> 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 X 3674 . T <*> 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 X 3675 . C <*> 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 X 3676 . T <*> 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 X 3677 . A <*> 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 X 3678 . G <*> 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 X 3679 . T <*> 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 X 3680 . T <*> 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 X 3681 . C <*> 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 X 3682 . A <*> 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 X 3683 . A <*> 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 X 3684 . A <*> 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 X 3685 . T <*> 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 X 3686 . T <*> 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 X 3687 . T <*> 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 X 3688 . A <*> 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 X 3689 . T <*> 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 X 3690 . T <*> 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 X 3691 . C <*> 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 X 3692 . A <*> 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 X 3693 . T <*> 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 X 3694 . T <*> 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 X 3695 . T <*> 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 X 3696 . T <*> 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 X 3697 . T <*> 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 X 3698 . A <*> 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 X 3699 . A <*> 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 X 3700 . C <*> 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 X 3701 . T <*> 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 X 3702 . T <*> 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 X 3703 . C <*> 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 X 3704 . A <*> 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 X 3705 . T <*> 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 X 3706 . A <*> 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 X 3707 . G <*> 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 X 3708 . T <*> 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 X 3709 . A <*> 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 X 3710 . C <*> 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 X 3711 . C <*> 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 X 3712 . A <*> 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 X 3713 . C <*> 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 X 3714 . A <*> 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 X 3715 . T <*> 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 X 3716 . T <*> 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 X 3717 . C <*> 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 X 3718 . T <*> 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 X 3719 . A <*> 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 X 3720 . C <*> 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 X 3721 . A <*> 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 X 3722 . C <*> 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 X 3723 . A <*> 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 X 3724 . C <*> 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 X 3725 . T <*> 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 X 3726 . G <*> 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 X 3727 . C <*> 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 X 3728 . C <*> 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 X 3729 . C <*> 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 X 3730 . A <*> 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 X 3731 . T <*> 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 X 3732 . G <*> 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 X 3733 . T <*> 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 X 3734 . C <*> 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 X 3735 . C <*> 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 X 3736 . C <*> 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 X 3737 . C <*> 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 X 3738 . T <*> 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 X 3739 . C <*> 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 X 3740 . A <*> 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 X 3741 . A <*> 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 X 3742 . G <*> 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 X 3743 . C <*> 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 X 3744 . T <*> 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 X 3745 . T <*> 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 X 3746 . C <*> 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 X 3747 . C <*> 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 X 3748 . C <*> 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 X 3749 . C <*> 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 X 3750 . T <*> 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 X 3751 . G <*> 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 X 3752 . G <*> 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 X 3753 . C <*> 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 X 3754 . T <*> 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 X 3755 . C <*> 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 X 3756 . C <*> 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 X 3757 . T <*> 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 X 3758 . G <*> 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 X 3759 . C <*> 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 X 3760 . A <*> 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 X 3761 . A <*> 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 X 3762 . C <*> 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 X 3763 . C <*> 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 X 3764 . A <*> 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 X 3765 . C <*> 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 X 3766 . A <*> 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 X 3767 . A <*> 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 X 3768 . A <*> 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 X 3769 . T <*> 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 X 3770 . C <*> 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 X 3771 . T <*> 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 X 3772 . A <*> 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 X 3773 . C <*> 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 X 3774 . T <*> 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 X 3775 . C <*> 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 X 3776 . T <*> 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 X 3777 . C <*> 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 X 3778 . T <*> 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 X 3779 . G <*> 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 X 3780 . C <*> 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 X 3781 . C <*> 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 X 3782 . T <*> 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 X 3783 . C <*> 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 X 3784 . T <*> 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 X 3785 . G <*> 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 X 3786 . T <*> 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 X 3787 . G <*> 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 X 3788 . G <*> 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 X 3789 . G <*> 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 X 3790 . T <*> 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 X 3791 . T <*> 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 X 3792 . G A,<*> 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 X 3793 . A <*> 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 X 3794 . C <*> 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 X 3795 . C <*> 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 X 3796 . T <*> 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 X 3797 . A <*> 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 X 3798 . T <*> 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 X 3799 . T <*> 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 X 3800 . C <*> 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 X 3801 . T <*> 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 X 3802 . G <*> 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 X 3803 . G <*> 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 X 3804 . A <*> 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 X 3805 . C <*> 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 X 3806 . A <*> 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 X 3807 . C <*> 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 X 3808 . G <*> 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 X 3809 . T <*> 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 X 3810 . C <*> 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 X 3811 . A C,<*> 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 X 3812 . T <*> 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 X 3813 . A <*> 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 X 3814 . G <*> 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 X 3815 . A <*> 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 X 3816 . A <*> 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 X 3817 . A <*> 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 X 3818 . T <*> 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 X 3819 . A <*> 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 X 3820 . G <*> 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 X 3821 . A <*> 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 X 3822 . G <*> 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 X 3823 . T <*> 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 X 3824 . C <*> 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 X 3825 . C <*> 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 X 3826 . T <*> 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 X 3827 . G <*> 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 X 3828 . C <*> 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 X 3829 . A <*> 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 X 3830 . A <*> 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 X 3831 . C A,<*> 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 X 3832 . A <*> 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 X 3833 . C <*> 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 X 3834 . G <*> 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 X 3835 . T <*> 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 X 3836 . G C,<*> 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 X 3837 . G <*> 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 X 3838 . C <*> 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 X 3839 . C <*> 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 X 3840 . G <*> 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 X 3841 . T <*> 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 X 3842 . C <*> 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 X 3843 . T <*> 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 X 3844 . G <*> 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 X 3845 . T <*> 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 X 3846 . G <*> 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 X 3847 . T <*> 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 X 3848 . C <*> 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 X 3849 . T <*> 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 X 3850 . G <*> 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 X 3851 . G <*> 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 X 3852 . C <*> 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 X 3853 . T <*> 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 X 3854 . T <*> 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 X 3855 . C <*> 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 X 3856 . T <*> 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 X 3857 . C <*> 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 X 3858 . T <*> 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 X 3859 . C <*> 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 X 3860 . G <*> 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 X 3861 . C <*> 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 X 3862 . T <*> 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 X 3863 . T <*> 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 X 3864 . A <*> 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 X 3865 . G <*> 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 X 3866 . C <*> 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 X 3867 . A <*> 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 X 3868 . T <*> 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 X 3869 . C <*> 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 X 3870 . T <*> 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 X 3871 . T <*> 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 X 3872 . G <*> 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 X 3873 . T <*> 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 X 3874 . T <*> 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 X 3875 . T <*> 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 X 3876 . C <*> 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 X 3877 . C <*> 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 X 3878 . A <*> 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 X 3879 . A <*> 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 X 3880 . G <*> 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 X 3881 . G <*> 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 X 3882 . T <*> 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 X 3883 . C <*> 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 X 3884 . C <*> 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 X 3885 . T <*> 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 X 3886 . C <*> 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 X 3887 . C <*> 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 X 3888 . C <*> 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 X 3889 . A <*> 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 X 3890 . C <*> 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 X 3891 . A <*> 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 X 3892 . G <*> 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 X 3893 . T <*> 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 X 3894 . G <*> 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 X 3895 . T <*> 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 X 3896 . A <*> 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 X 3897 . G <*> 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 X 3898 . C <*> 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 X 3899 . A <*> 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 X 3900 . T <*> 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 X 3901 . G <*> 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 X 3902 . C <*> 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 X 3903 . A <*> 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 X 3904 . C <*> 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 X 3905 . C <*> 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 X 3906 . T <*> 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 X 3907 . G <*> 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 X 3908 . C <*> 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 X 3909 . T <*> 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 X 3910 . A <*> 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 X 3911 . C <*> 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 X 3912 . A C,<*> 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 X 3913 . C <*> 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 X 3914 . T <*> 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 X 3915 . C <*> 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 X 3916 . C <*> 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 X 3917 . T <*> 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 X 3918 . T <*> 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 X 3919 . C <*> 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 X 3920 . T <*> 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 X 3921 . T <*> 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 X 3922 . A <*> 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 X 3923 . G <*> 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 X 3924 . G <*> 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 X 3925 . G <*> 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 X 3926 . C <*> 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 X 3927 . T <*> 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 X 3928 . G <*> 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 X 3929 . A <*> 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 X 3930 . T <*> 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 X 3931 . A <*> 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 X 3932 . T <*> 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 X 3933 . T <*> 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 X 3934 . C <*> 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 X 3935 . C <*> 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 X 3936 . A G,<*> 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 X 3937 . C <*> 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 X 3938 . G <*> 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 X 3939 . C <*> 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 X 3940 . A <*> 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 X 3941 . C <*> 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 X 3942 . C <*> 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 X 3943 . T <*> 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 X 3944 . G <*> 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 X 3945 . C <*> 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 X 3946 . T <*> 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 X 3947 . A <*> 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 X 3948 . C <*> 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 X 3949 . A C,<*> 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 X 3950 . C <*> 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 X 3951 . T <*> 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 X 3952 . C <*> 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 X 3953 . C <*> 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 X 3954 . T <*> 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 X 3955 . T <*> 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 X 3956 . C <*> 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 X 3957 . T <*> 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 X 3958 . T <*> 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 X 3959 . A <*> 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 X 3960 . T <*> 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 X 3961 . G <*> 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 X 3962 . G <*> 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 X 3963 . C <*> 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 X 3964 . T <*> 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 X 3965 . G <*> 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 X 3966 . A <*> 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 X 3967 . T <*> 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 X 3968 . A <*> 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 X 3969 . T <*> 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 X 3970 . T <*> 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 X 3971 . C <*> 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 X 3972 . C <*> 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 X 3973 . A <*> 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 X 3974 . C <*> 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 X 3975 . G <*> 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 X 3976 . C <*> 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 X 3977 . A <*> 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 X 3978 . C <*> 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 X 3979 . C <*> 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 X 3980 . T <*> 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 X 3981 . G <*> 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 X 3982 . C <*> 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 X 3983 . T <*> 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 X 3984 . A <*> 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 X 3985 . C <*> 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 X 3986 . A <*> 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 X 3987 . C <*> 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 X 3988 . T <*> 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 X 3989 . C <*> 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 X 3990 . C <*> 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 X 3991 . T <*> 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 X 3992 . T <*> 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 X 3993 . C <*> 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 X 3994 . T <*> 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 X 3995 . T <*> 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 X 3996 . A <*> 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 X 3997 . G C,<*> 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 X 3998 . G <*> 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 X 3999 . G A,<*> 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 X 4000 . C <*> 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 X 4001 . T <*> 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 X 4002 . G <*> 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 X 4003 . A <*> 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 X 4004 . T <*> 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 X 4005 . A <*> 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 X 4006 . T <*> 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 X 4007 . T G,<*> 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 X 4008 . C <*> 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 X 4009 . C <*> 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 X 4010 . A <*> 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 X 4011 . C <*> 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 X 4012 . A <*> 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 X 4013 . C <*> 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 X 4014 . A <*> 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 X 4015 . C <*> 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 X 4016 . C <*> 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 X 4017 . C <*> 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 X 4018 . G <*> 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 X 4019 . C <*> 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 X 4020 . T <*> 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 X 4021 . A <*> 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 X 4022 . C <*> 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 X 4023 . A <*> 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 X 4024 . C <*> 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 X 4025 . T <*> 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 X 4026 . C <*> 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 X 4027 . C <*> 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 X 4028 . T <*> 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 X 4029 . T <*> 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 X 4030 . C <*> 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 X 4031 . T <*> 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 X 4032 . T <*> 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 X 4033 . A <*> 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 X 4034 . G <*> 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 X 4035 . G T,<*> 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 X 4036 . G <*> 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 X 4037 . C <*> 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 X 4038 . T <*> 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 X 4039 . G <*> 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 X 4040 . A <*> 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 X 4041 . T <*> 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 X 4042 . A <*> 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 X 4043 . T <*> 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 X 4044 . T <*> 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 X 4045 . C <*> 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 X 4046 . C <*> 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 X 4047 . A <*> 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 X 4048 . C <*> 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 X 4049 . G <*> 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 X 4050 . C <*> 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 X 4051 . A <*> 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 X 4052 . C <*> 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 X 4053 . C <*> 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 X 4054 . C <*> 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 X 4055 . G <*> 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 X 4056 . C <*> 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 X 4057 . T <*> 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 X 4058 . A <*> 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 X 4059 . C <*> 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 X 4060 . A <*> 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 X 4061 . C <*> 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 X 4062 . T <*> 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 X 4063 . C <*> 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 X 4064 . C <*> 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 X 4065 . T <*> 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 X 4066 . T <*> 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 X 4067 . C <*> 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 X 4068 . T <*> 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 X 4069 . T <*> 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 X 4070 . A <*> 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 X 4071 . G <*> 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 X 4072 . G <*> 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 X 4073 . G <*> 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 X 4074 . C <*> 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 X 4075 . T <*> 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 X 4076 . G <*> 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 X 4077 . A <*> 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 X 4078 . T <*> 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 X 4079 . A <*> 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 X 4080 . T <*> 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 X 4081 . T <*> 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 X 4082 . C <*> 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 X 4083 . C <*> 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 X 4084 . A <*> 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 X 4085 . C <*> 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 X 4086 . G <*> 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 X 4087 . C <*> 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 X 4088 . A <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 X 4089 . C <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 X 4090 . C <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 X 4091 . T <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 X 4092 . G <*> 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 X 4093 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 X 4094 . T <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 X 4095 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 X 4096 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 X 4097 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 X 4098 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 X 4099 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 X 4100 . C <*> 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 X 4101 . C <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 bcftools-1.21/test/mpileup.c.vcf000066400000000000000000023604431467060157400166510ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 1 . A 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 2 . A 0 . DP=11;I16=11,0,0,0,439,17587,0,0,319,9251,0,0,226,5030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 3 . G 0 . DP=11;I16=11,0,0,0,431,16971,0,0,319,9251,0,0,229,5111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 4 . C 0 . DP=11;I16=11,0,0,0,423,16417,0,0,319,9251,0,0,232,5202,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,71:3:0 17 5 . T 0 . DP=11;I16=11,0,0,0,450,18520,0,0,319,9251,0,0,234,5252,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 6 . T 0 . DP=11;I16=11,0,0,0,403,14847,0,0,319,9251,0,0,236,5310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 7 . C 0 . DP=11;I16=11,0,0,0,446,18114,0,0,319,9251,0,0,237,5327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 8 . T 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 9 . C 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 10 . A 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 17 11 . C 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 12 . C 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 13 . C 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 14 . T 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 15 . G 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 16 . T 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 17 . T 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 18 . C 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 17 19 . C 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 17 20 . T 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 17 21 . G 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 17 22 . C 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 17 23 . A 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 17 24 . T 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 17 25 . A 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 17 26 . G 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 17 27 . A 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 17 28 . T 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 17 29 . A 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 17 30 . A 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 17 31 . T 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 17 32 . T 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 17 33 . G 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 17 34 . C 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 17 35 . A 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 17 36 . T 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 17 37 . G 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 17 38 . A 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 17 39 . C 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 17 40 . A 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 17 41 . A 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 17 42 . T 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 17 43 . T 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 17 44 . G 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 17 45 . C 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 17 46 . C 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 17 47 . T 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 17 48 . T 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 17 49 . G 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 17 50 . T 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 17 51 . C 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 17 52 . C 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 17 53 . C 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 17 54 . T 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 17 55 . G 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 17 56 . C 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 17 57 . T 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 17 58 . G 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 17 59 . A 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 17 60 . A 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 17 61 . T 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 17 62 . G 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 17 63 . T 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 17 64 . G 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 17 65 . C 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 17 66 . T 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 17 67 . C 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 17 68 . T 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 17 69 . G 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 17 70 . G 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 17 71 . G 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 17 72 . G 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 17 73 . T 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 17 74 . C 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 17 75 . T 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 17 76 . C 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 17 77 . T 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 17 78 . G 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 17 79 . G 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 17 80 . G 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 17 81 . G 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 17 82 . T 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 17 83 . C 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 17 84 . T 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 17 85 . C 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 17 86 . A 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 17 87 . C 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 17 88 . C 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 17 89 . C 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 17 90 . A 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 17 91 . C 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 17 92 . G 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 17 93 . A 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 17 94 . C 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 17 95 . C 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 17 96 . A 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 17 97 . A 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 17 98 . C 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 17 99 . T 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 17 100 . C 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 17 101 . C 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 17 102 . C 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 17 103 . T 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 17 104 . G 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 17 105 . G 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 17 106 . G 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 17 107 . C 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 17 108 . C 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 17 109 . T 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 17 110 . G 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 17 111 . G 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 17 112 . C 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 17 113 . A 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 17 114 . C 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 17 115 . C 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 17 116 . A 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 17 117 . G 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 17 118 . G 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 17 119 . G 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 17 120 . A 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 17 121 . G 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 17 122 . C 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 17 123 . T 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 17 124 . T 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 17 125 . A 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 17 126 . A 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 17 127 . C 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 17 128 . A 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 17 129 . A 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 17 130 . A 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 17 131 . C 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 17 132 . A 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 17 133 . T 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 17 134 . C 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 17 135 . T 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 17 136 . G 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 17 137 . T 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 17 138 . C 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 17 139 . C 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 17 140 . A 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 17 141 . G 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 17 142 . C 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 17 143 . G 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 17 144 . A 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 17 145 . A 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 17 146 . T 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 17 147 . A 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 17 148 . C 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 17 149 . C 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 17 150 . T 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 17 151 . G 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 17 152 . C 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 17 153 . A 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 17 154 . T 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 17 155 . C 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 17 156 . C 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 17 157 . C 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 17 158 . T 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 17 159 . A 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 17 160 . G 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 17 161 . A 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 17 162 . A 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 17 163 . G 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 17 164 . T 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 17 165 . G 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 17 166 . A 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 17 167 . A 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 17 168 . G 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 17 169 . C 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 17 170 . C 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 17 171 . A 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 17 172 . C 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 17 173 . C 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 17 174 . G 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 17 175 . C 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 17 176 . C 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 17 177 . C 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 17 178 . A 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 17 179 . A 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 17 180 . A 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 17 181 . G 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 17 182 . A 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 17 183 . C 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 17 184 . A 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 17 185 . C 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 17 186 . G 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 17 187 . C 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 17 188 . C 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 17 189 . C 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 17 190 . A 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 17 191 . T 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 17 192 . G 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 17 193 . T 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 17 194 . C 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 17 195 . C 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 17 196 . A 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 17 197 . G 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 17 198 . C 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 17 199 . T 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 17 200 . T 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 17 201 . A 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 17 202 . A 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 17 203 . C 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 17 204 . C 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 17 205 . T 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 17 206 . G 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 17 207 . C 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 17 208 . A 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 17 209 . T 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 17 210 . C 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 17 211 . C 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 17 212 . C 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 17 213 . T 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 17 214 . A 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 17 215 . G 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 17 216 . A 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 17 217 . A 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 17 218 . G 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 17 219 . T 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 17 220 . G 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 17 221 . A 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 17 222 . A 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 17 223 . G 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 17 224 . G 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 17 225 . C 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 17 226 . A 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 17 227 . C 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 17 228 . C 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 17 229 . G 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 17 230 . C 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 17 231 . C 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 17 232 . C 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 17 233 . A 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 17 234 . A 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 17 235 . A 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 17 236 . G 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 17 237 . A 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 17 238 . C 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 17 239 . A 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 17 240 . C 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 17 241 . G 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 17 242 . C 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 17 243 . C 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 17 244 . C 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 17 245 . A 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 17 246 . T 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 17 247 . G 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 17 248 . T 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 17 249 . C 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 17 250 . C 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 17 251 . A 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 17 252 . G 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 17 253 . C 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 17 254 . T 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 17 255 . T 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 17 256 . A 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 17 257 . T 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 17 258 . T 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 17 259 . C 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 17 260 . T 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 17 261 . G 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 17 262 . C 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 17 263 . C 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 17 264 . C 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 17 265 . A 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 17 266 . G 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 17 267 . T 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 17 268 . T 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 17 269 . C 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 17 270 . C 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 17 271 . T 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 17 272 . C 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 17 273 . T 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 17 274 . C 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 17 275 . C 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 17 276 . A 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 17 277 . G 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 17 278 . A 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 17 279 . A 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 17 280 . A 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 17 281 . G 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 17 282 . G 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 17 283 . C 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 17 284 . T 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 17 285 . G 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 17 286 . C 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 17 287 . A 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 17 288 . T 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 17 289 . G 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 17 290 . G 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 17 291 . T 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 17 292 . T 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 17 293 . G 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 17 294 . A 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 17 295 . C 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 17 296 . A 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 17 297 . C 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 17 298 . A 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 17 299 . C 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 17 300 . A 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 17 301 . G 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 17 302 . T 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 17 303 . G 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 17 304 . C 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 17 305 . C 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 17 306 . T 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 17 307 . G 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 17 308 . C 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 17 309 . G 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 17 310 . A 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 17 311 . C 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 17 312 . A 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 17 313 . A 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 17 314 . A 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 17 315 . G 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 17 316 . C 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 17 317 . T 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 17 318 . G 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 17 319 . A 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 17 320 . A 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 17 321 . T 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 17 322 . G 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 17 323 . C 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 17 324 . T 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 17 325 . A 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 17 326 . T 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 17 327 . C 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 17 328 . A 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 17 329 . T 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 17 330 . T 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 17 331 . T 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 17 332 . A 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 17 333 . A 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 17 334 . A 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 17 335 . A 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 17 336 . A 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 17 337 . C 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 17 338 . T 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 17 339 . C 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 17 340 . C 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 17 341 . T 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 17 342 . T 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 17 343 . G 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 17 344 . C 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 17 345 . T 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 17 346 . G 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 17 347 . G 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 17 348 . T 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 17 349 . T 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 17 350 . T 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 17 351 . G 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 17 352 . A 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 17 353 . G 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 17 354 . A 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 17 355 . G T, 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 17 356 . G 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 17 357 . C 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 17 358 . A 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 17 359 . G 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 17 360 . A 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 17 361 . A 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 17 362 . A 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 17 363 . A 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 17 364 . T 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 17 365 . G 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 17 366 . A 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 17 367 . T 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 17 368 . A 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 17 369 . T 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 17 370 . C 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 17 371 . T 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 17 372 . C 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 17 373 . A 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 17 374 . T 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 17 375 . A T, 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 17 376 . G 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 17 377 . T 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 17 378 . T 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 17 379 . G 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 17 380 . C 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 17 381 . T 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 17 382 . T 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 17 383 . T 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 17 384 . A 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 17 385 . C 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 17 386 . T 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 17 387 . T 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 17 388 . T 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 17 389 . G 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 17 390 . C 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 17 391 . A 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 17 392 . T 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 17 393 . A 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 17 394 . T 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 17 395 . T 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 17 396 . T 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 17 397 . T 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 17 398 . A 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 17 399 . A 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 17 400 . A 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 17 401 . A 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 17 402 . T 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 17 403 . T 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 17 404 . G 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 17 405 . T 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 17 406 . G 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 17 407 . A 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 17 408 . C 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 17 409 . T 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 17 410 . T 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 17 411 . T 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 17 412 . C T, 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 17 413 . A 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 17 414 . T 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 17 415 . G 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 17 416 . G 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 17 417 . C 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 17 418 . A 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 17 419 . T 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 17 420 . A 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 17 421 . A 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 17 422 . A 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 17 423 . T 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 17 424 . A 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 17 425 . A 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 17 426 . T 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 17 427 . A 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 17 428 . C 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 17 429 . T 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 17 430 . G 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 17 431 . G 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 17 432 . T 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 17 433 . T 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 17 434 . T 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 17 435 . A 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 17 436 . T 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 17 437 . T 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 17 438 . A 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 17 439 . C 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 17 440 . A 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 17 441 . G 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 17 442 . A 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 17 443 . A 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 17 444 . G 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 17 445 . C 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 17 446 . A 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 17 447 . C 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 17 448 . T 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 17 449 . A 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 17 450 . G 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 17 451 . A 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 17 452 . A 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 17 453 . A 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 17 454 . A 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 17 455 . T 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 17 456 . G 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 17 457 . C 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 17 458 . A 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 17 459 . T 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 17 460 . G 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 17 461 . T 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 17 462 . G 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 17 463 . G 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 17 464 . A 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 17 465 . C 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 17 466 . A 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 17 467 . A 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 17 468 . A 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 17 469 . A 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 17 470 . G 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 17 471 . T 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 17 472 . T 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 17 473 . G 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 17 474 . G 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 17 475 . G 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 17 476 . A 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 17 477 . T 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 17 478 . T 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 17 479 . A 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 17 480 . G 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 17 481 . G 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 17 482 . A 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 17 483 . G 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 17 484 . A 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 17 485 . G 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 17 486 . A 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 17 487 . G 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 17 488 . A 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 17 489 . A 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 17 490 . A 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 17 491 . T 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 17 492 . G 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 17 493 . A 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 17 494 . A 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 17 495 . G 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 17 496 . A 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 17 497 . C 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 17 498 . A 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 17 499 . T 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 17 500 . A 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 17 501 . T 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 17 502 . G 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 17 503 . T 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 17 504 . C 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 17 505 . C 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 17 506 . A 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 17 507 . C 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 17 508 . A 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 17 509 . C 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 17 510 . A 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 17 511 . A 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 17 512 . A C, 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 17 513 . A 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 17 514 . A T, 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 17 515 . C 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 17 516 . C 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 17 517 . T 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 17 518 . G 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 17 519 . T 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 17 520 . T 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 17 521 . C 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 17 522 . A 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 17 523 . T G, 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 17 524 . T 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 17 525 . G 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 17 526 . C 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 17 527 . A 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 17 528 . G 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 17 529 . C 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 17 530 . T 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 17 531 . T 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 17 532 . T 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 17 533 . C 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 17 534 . T 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 17 535 . A 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 17 536 . C 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 17 537 . C 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 17 538 . A 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 17 539 . T 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 17 540 . C 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 17 541 . A 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 17 542 . C 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 17 543 . C 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 17 544 . A 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 17 545 . A 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 17 546 . A 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 17 547 . A 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 17 548 . A 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 17 549 . T G, 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 17 550 . T 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 17 551 . G 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 17 552 . C 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 17 553 . A 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 17 554 . A 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 17 555 . A 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 17 556 . C 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 17 557 . A 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 17 558 . A 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 17 559 . C A, 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 17 560 . C 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 17 561 . A 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 17 562 . C 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 17 563 . A 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 17 564 . C 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 17 565 . G 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 17 566 . C 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 17 567 . C 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 17 568 . C 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 17 569 . T 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 17 570 . T 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 17 571 . C 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 17 572 . A 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 17 573 . A 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 17 574 . C A, 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 17 575 . T 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 17 576 . G 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 17 577 . G 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 17 578 . G 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 17 579 . G 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 17 580 . A C, 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 17 581 . A 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 17 582 . C 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 17 583 . T 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 17 584 . C 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 17 585 . A 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 17 586 . T 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 17 587 . C 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 17 588 . A 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 17 589 . A 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 17 590 . C 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 17 591 . A 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 17 592 . A 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 17 593 . C 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 17 594 . A 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 17 595 . A 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 17 596 . A 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 17 597 . C 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 17 598 . T 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 17 599 . T 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 17 600 . G 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 17 601 . T 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 17 602 . G 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 17 603 . G 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 17 604 . T 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 17 605 . T 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 17 606 . T 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 17 607 . A 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 17 608 . C 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 17 609 . C 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 17 610 . C 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 17 611 . A 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 17 612 . C 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 17 613 . A 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 17 614 . C 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 17 615 . A 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 17 616 . A 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 17 617 . T 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 17 618 . G 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 17 619 . G 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 17 620 . A 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 17 621 . A 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 17 622 . G 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 17 623 . A T, 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 17 624 . C 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 17 625 . C 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 17 626 . A 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 17 627 . C 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 17 628 . T 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 17 629 . T 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 17 630 . A 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 17 631 . G 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 17 632 . C 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 17 633 . A 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 17 634 . A 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 17 635 . C 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 17 636 . A 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 17 637 . A 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 17 638 . A 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 17 639 . A 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 17 640 . A 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 17 641 . G 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 17 642 . G 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 17 643 . A 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 17 644 . C A, 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 17 645 . C 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 17 646 . A T, 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 17 647 . A 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 17 648 . A 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 17 649 . C 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 17 650 . T 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 17 651 . C 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 17 652 . C 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 17 653 . T 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 17 654 . G 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 17 655 . G 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 17 656 . T 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 17 657 . A 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 17 658 . C 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 17 659 . A 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 17 660 . T 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 17 661 . G 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 17 662 . C 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 17 663 . A 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 17 664 . A 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 17 665 . C 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 17 666 . T 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 17 667 . G 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 17 668 . A 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 17 669 . C 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 17 670 . A 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 17 671 . G 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 17 672 . A 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 17 673 . T 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 17 674 . G 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 17 675 . A 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 17 676 . A 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 17 677 . T 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 17 678 . C 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 17 679 . T 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 17 680 . C 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 17 681 . A 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 17 682 . A 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 17 683 . A 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 17 684 . C 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 17 685 . G 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 17 686 . C 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 17 687 . A 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 17 688 . T 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 17 689 . T A, 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 17 690 . C 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 17 691 . C 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 17 692 . T 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 17 693 . C 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 17 694 . C 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 17 695 . G 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 17 696 . T 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 17 697 . G 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 17 698 . T 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 17 699 . G 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 17 700 . A 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 17 701 . A 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 17 702 . A 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 17 703 . G 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 17 704 . A T, 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 17 705 . A 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 17 706 . G 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 17 707 . C 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 17 708 . C 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 17 709 . G 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 17 710 . G 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 17 711 . A 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 17 712 . C 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 17 713 . T 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 17 714 . C 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 17 715 . A 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 17 716 . C 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 17 717 . A 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 17 718 . G 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 17 719 . G 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 17 720 . G 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 17 721 . C 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 17 722 . A 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 17 723 . A 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 17 724 . C 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 17 725 . A 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 17 726 . C 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 17 727 . A C, 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 17 728 . C 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 17 729 . T 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 17 730 . A 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 17 731 . T 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 17 732 . C 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 17 733 . T 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 17 734 . G 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 17 735 . A 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 17 736 . C 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 17 737 . T 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 17 738 . G 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 17 739 . T 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 17 740 . T 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 17 741 . T 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 17 742 . C 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 17 743 . A 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 17 744 . T 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 17 745 . G 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 17 746 . G 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 17 747 . G 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 17 748 . A 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 17 749 . A 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 17 750 . A 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 17 751 . G 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 17 752 . T 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 17 753 . C 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 17 754 . T 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 17 755 . G 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 17 756 . G 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 17 757 . A 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 17 758 . A 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 17 759 . A 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 17 760 . C 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 17 761 . G 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 17 762 . G 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 17 763 . C A, 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 17 764 . A 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 17 765 . A 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 17 766 . C 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 17 767 . A 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 17 768 . C 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 17 769 . C 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 17 770 . A 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 17 771 . T 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 17 772 . T 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 17 773 . G 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 17 774 . A 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 17 775 . G 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 17 776 . A 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 17 777 . C 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 17 778 . A 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 17 779 . G 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 17 780 . A 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 17 781 . A 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 17 782 . A 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 17 783 . A 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 17 784 . C 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 17 785 . A 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 17 786 . G 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 17 787 . G 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 17 788 . T 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 17 789 . G 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 17 790 . A 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 17 791 . G 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 17 792 . T 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 17 793 . G 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 17 794 . G 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 17 795 . T 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 17 796 . T 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 17 797 . G 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 17 798 . C 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 17 799 . C 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 17 800 . T 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 17 801 . G 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 17 802 . G 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 17 803 . G 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 17 804 . G 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 17 805 . C 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 17 806 . C 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 17 807 . A 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 17 808 . G 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 17 809 . G 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 17 810 . G C, 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 17 811 . A 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 17 812 . A 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 17 813 . C 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 17 814 . T 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 17 815 . T 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 17 816 . T 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 17 817 . C 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 17 818 . T 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 17 819 . G 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 17 820 . G 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 17 821 . G 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 17 822 . G 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 17 823 . T 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 17 824 . C 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 17 825 . A 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 17 826 . T 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 17 827 . A 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 17 828 . T C, 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 17 829 . T 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 17 830 . C 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 17 831 . T 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 17 832 . C 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 17 833 . T 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 17 834 . G A, 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 17 835 . T 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 17 836 . G 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 17 837 . T 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 17 838 . T 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 17 839 . G 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 17 840 . A 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 17 841 . T 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 17 842 . T 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 17 843 . C 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 17 844 . T 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 17 845 . G 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 17 846 . G 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 17 847 . T 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 17 848 . G 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 17 849 . G 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 17 850 . T 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 17 851 . G 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 17 852 . G 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 17 853 . A 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 17 854 . A 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 17 855 . A 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 17 856 . C 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 17 857 . A 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 17 858 . A 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 17 859 . G 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 17 860 . A 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 17 861 . C 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 17 862 . T 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 17 863 . G 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 17 864 . T 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 17 865 . C 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 17 866 . C 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 17 867 . C 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 17 868 . A 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 17 869 . G 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 17 870 . C 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 17 871 . C 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 17 872 . T 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 17 873 . G 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 17 874 . G 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 17 875 . G 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 17 876 . T 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 17 877 . G 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 17 878 . A 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 17 879 . T 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 17 880 . A 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 17 881 . C 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 17 882 . A 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 17 883 . G 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 17 884 . C 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 17 885 . G 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 17 886 . A 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 17 887 . G 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 17 888 . A 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 17 889 . C 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 17 890 . C 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 17 891 . C 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 17 892 . C 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 17 893 . A 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 17 894 . T 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 17 895 . C 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 17 896 . T 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 17 897 . C 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 17 898 . T 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 17 899 . A 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 17 900 . C 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 17 901 . C 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 17 902 . A 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 17 903 . A 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 17 904 . A 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 17 905 . A 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 17 906 . A 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 17 907 . A 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 17 908 . T 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 17 909 . T 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 17 910 . A 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 17 911 . A 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 17 912 . A 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 17 913 . A 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 17 914 . A 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 17 915 . T 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 17 916 . T 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 17 917 . A 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 17 918 . G 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 17 919 . C 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 17 920 . T 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 17 921 . G 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 17 922 . G 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 17 923 . G 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 17 924 . C 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 17 925 . A 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 17 926 . T 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 17 927 . G 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 17 928 . G 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 17 929 . T 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 17 930 . G 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 17 931 . G 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 17 932 . T 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 17 933 . G 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 17 934 . C 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 17 935 . A 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 17 936 . T 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 17 937 . G 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 17 938 . C 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 17 939 . C 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 17 940 . T 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 17 941 . G 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 17 942 . T 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 17 943 . A 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 17 944 . G 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 17 945 . T 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 17 946 . C 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 17 947 . C 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 17 948 . C 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 17 949 . A 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 17 950 . G 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 17 951 . C 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 17 952 . T 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 17 953 . A 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 17 954 . T 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 17 955 . T 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 17 956 . C 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 17 957 . A 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 17 958 . C 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 17 959 . A 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 17 960 . G 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 17 961 . T 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 17 962 . G 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 17 963 . C 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 17 964 . T 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 17 965 . G 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 17 966 . A 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 17 967 . G 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 17 968 . G 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 17 969 . T 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 17 970 . G 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 17 971 . G 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 17 972 . G 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 17 973 . A 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 17 974 . A 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 17 975 . G 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 17 976 . A 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 17 977 . T 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 17 978 . G 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 17 979 . C 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 17 980 . T 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 17 981 . T 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 17 982 . G 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 17 983 . A 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 17 984 . G 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 17 985 . C 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 17 986 . C A, 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 17 987 . C 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 17 988 . A 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 17 989 . G 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 17 990 . G 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 17 991 . A 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 17 992 . G 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 17 993 . T 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 17 994 . T 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 17 995 . C 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 17 996 . A 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 17 997 . A 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 17 998 . G 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 17 999 . G 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 17 1000 . C 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 17 1001 . T 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 17 1002 . G 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 17 1003 . C T, 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 17 1004 . A 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 17 1005 . A 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 17 1006 . T 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 17 1007 . G 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 17 1008 . A 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 17 1009 . G 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 17 1010 . C 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 17 1011 . T 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 17 1012 . A 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 17 1013 . T 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 17 1014 . G 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 17 1015 . A 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 17 1016 . T 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 17 1017 . T 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 17 1018 . G 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 17 1019 . C 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 17 1020 . G 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 17 1021 . C 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 17 1022 . C 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 17 1023 . A 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 17 1024 . C 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 17 1025 . T 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 17 1026 . G 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 17 1027 . C 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 17 1028 . A 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 17 1029 . C 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 17 1030 . T 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 17 1031 . T 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 17 1032 . T 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 17 1033 . G 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 17 1034 . G 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 17 1035 . C 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 17 1036 . C 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 17 1037 . T 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 17 1038 . G 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 17 1039 . G 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 17 1040 . A 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 17 1041 . C 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 17 1042 . A 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 17 1043 . A 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 17 1044 . C 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 17 1045 . A 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 17 1046 . G 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 17 1047 . A 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 17 1048 . G 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 17 1049 . C 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 17 1050 . A 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 17 1051 . A 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 17 1052 . A 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 17 1053 . A 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 17 1054 . C 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 17 1055 . C 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 17 1056 . C 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 17 1057 . T 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 17 1058 . G 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 17 1059 . T 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 17 1060 . C 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 17 1061 . T 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 17 1062 . C A, 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 17 1063 . T 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 17 1064 . A 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 17 1065 . A 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 17 1066 . A 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 17 1067 . A 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 17 1068 . A 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 17 1069 . A 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 17 1070 . A 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 17 1071 . G 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 17 1072 . A 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 17 1073 . A 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 17 1074 . A 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 17 1075 . A 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 17 1076 . G 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 17 1077 . A 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 17 1078 . A 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 17 1079 . A 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 17 1080 . A 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 17 1081 . G 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 17 1082 . A 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 17 1083 . A 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 17 1084 . A 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 17 1085 . A 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 17 1086 . A 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 17 1087 . C 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 17 1088 . T 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 17 1089 . C 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 17 1090 . A 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 17 1091 . C 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 17 1092 . T 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 17 1093 . G 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 17 1094 . G 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 17 1095 . A 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 17 1096 . T 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 17 1097 . A 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 17 1098 . T 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 17 1099 . G 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 17 1100 . A 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 17 1101 . A 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 17 1102 . T 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 17 1103 . G 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 17 1104 . A 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 17 1105 . T 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 17 1106 . A 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 17 1107 . C 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 17 1108 . A 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 17 1109 . G 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 17 1110 . G 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 17 1111 . T 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 17 1112 . T 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 17 1113 . G 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 17 1114 . A 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 17 1115 . G 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 17 1116 . G 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 17 1117 . A 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 17 1118 . T 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 17 1119 . C 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 17 1120 . C 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 17 1121 . A 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 17 1122 . T 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 17 1123 . T 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 17 1124 . A 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 17 1125 . T 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 17 1126 . C 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 17 1127 . T 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 17 1128 . G 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 17 1129 . A G, 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 17 1130 . A 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 17 1131 . A 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 17 1132 . T 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 17 1133 . G 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 17 1134 . C 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 17 1135 . T 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 17 1136 . T 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 17 1137 . G 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 17 1138 . G 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 17 1139 . A 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 17 1140 . C 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 17 1141 . C 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 17 1142 . A 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 17 1143 . G 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 17 1144 . A 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 17 1145 . T 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 17 1146 . G 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 17 1147 . T 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 17 1148 . T 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 17 1149 . T 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 17 1150 . T 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 17 1151 . G 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 17 1152 . A 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 17 1153 . A 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 17 1154 . T 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 17 1155 . T 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 17 1156 . T 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 17 1157 . T 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 17 1158 . G 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 17 1159 . G 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 17 1160 . A 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 17 1161 . T 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 17 1162 . T 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 17 1163 . T 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 17 1164 . T 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 17 1165 . T 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 17 1166 . T 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 17 1167 . C 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 17 1168 . A 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 17 1169 . T 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 17 1170 . A 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 17 1171 . T 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 17 1172 . T 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 17 1173 . T 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 17 1174 . T 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 17 1175 . G 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 17 1176 . T 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 17 1177 . A 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 17 1178 . A 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 17 1179 . T 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 17 1180 . C 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 17 1181 . T 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 17 1182 . T 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 17 1183 . T 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 17 1184 . G 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 17 1185 . C 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 17 1186 . A 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 17 1187 . G 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 17 1188 . T 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 17 1189 . A 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 17 1190 . T 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 17 1191 . A 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 17 1192 . T 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 17 1193 . T 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 17 1194 . T 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 17 1195 . A 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 17 1196 . C 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 17 1197 . C 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 17 1198 . A 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 17 1199 . G 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 17 1200 . T 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 17 1201 . T 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 17 1202 . C 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 17 1203 . A 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 17 1204 . G 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 17 1205 . C 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 17 1206 . A 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 17 1207 . T 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 17 1208 . C 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 17 1209 . C T, 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 17 1210 . C 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 17 1211 . T 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 17 1212 . A 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 17 1213 . A 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 17 1214 . C 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 17 1215 . T 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 17 1216 . C 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 17 1217 . A 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 17 1218 . A 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 17 1219 . A 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 17 1220 . A 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 17 1221 . A 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 17 1222 . T 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 17 1223 . T 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 17 1224 . C 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 17 1225 . A 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 17 1226 . A 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 17 1227 . A 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 17 1228 . A 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 17 1229 . A 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 17 1230 . T 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 17 1231 . C 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 17 1232 . T 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 17 1233 . G 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 17 1234 . A 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 17 1235 . A 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 17 1236 . A 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 17 1237 . T 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 17 1238 . C 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 17 1239 . C 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 17 1240 . C 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 17 1241 . A 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 17 1242 . A 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 17 1243 . A 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 17 1244 . C 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 17 1245 . G 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 17 1246 . C 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 17 1247 . G 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 17 1248 . C 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 17 1249 . C 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 17 1250 . A 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 17 1251 . A 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 17 1252 . T 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 17 1253 . A 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 17 1254 . A 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 17 1255 . G 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 17 1256 . C 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 17 1257 . A 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 17 1258 . T 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 17 1259 . T 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 17 1260 . C 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 17 1261 . C 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 17 1262 . C 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 17 1263 . T 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 17 1264 . T 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 17 1265 . T 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 17 1266 . G 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 17 1267 . A 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 17 1268 . G 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 17 1269 . C 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 17 1270 . G 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 17 1271 . T 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 17 1272 . C 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 17 1273 . A 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 17 1274 . T 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 17 1275 . G 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 17 1276 . T 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 17 1277 . C 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 17 1278 . G 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 17 1279 . G 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 17 1280 . T 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 17 1281 . G 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 17 1282 . C 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 17 1283 . T 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 17 1284 . T 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 17 1285 . G 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 17 1286 . G 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 17 1287 . A 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 17 1288 . A 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 17 1289 . T 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 17 1290 . G 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 17 1291 . T 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 17 1292 . T 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 17 1293 . T 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 17 1294 . G 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 17 1295 . G 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 17 1296 . G 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 17 1297 . G 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 17 1298 . T 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 17 1299 . T 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 17 1300 . T 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 17 1301 . T G, 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 17 1302 . G 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 17 1303 . G 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 17 1304 . A 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 17 1305 . T 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 17 1306 . T 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 17 1307 . T 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 17 1308 . A 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 17 1309 . C 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 17 1310 . A 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 17 1311 . G 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 17 1312 . C 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 17 1313 . T 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 17 1314 . T 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 17 1315 . T 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 17 1316 . G 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 17 1317 . G 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 17 1318 . G 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 17 1319 . A 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 17 1320 . C 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 17 1321 . G 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 17 1322 . C 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 17 1323 . T 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 17 1324 . C 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 17 1325 . A 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 17 1326 . A 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 17 1327 . C 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 17 1328 . C 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 17 1329 . T 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 17 1330 . G 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 17 1331 . T 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 17 1332 . A 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 17 1333 . C 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 17 1334 . C 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 17 1335 . T 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 17 1336 . C 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 17 1337 . A 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 17 1338 . A 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 17 1339 . T 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 17 1340 . A 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 17 1341 . A 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 17 1342 . A 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 17 1343 . C 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 17 1344 . C 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 17 1345 . T 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 17 1346 . G 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 17 1347 . A 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 17 1348 . T 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 17 1349 . T 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 17 1350 . T 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 17 1351 . T 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 17 1352 . A 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 17 1353 . A 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 17 1354 . A 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 17 1355 . A 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 17 1356 . A 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 17 1357 . A 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 17 1358 . G 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 17 1359 . T 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 17 1360 . T 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 17 1361 . T 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 17 1362 . G 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 17 1363 . G 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 17 1364 . G 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 17 1365 . G 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 17 1366 . G 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 17 1367 . G C, 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 17 1368 . A 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 17 1369 . T 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 17 1370 . T 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 17 1371 . C 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 17 1372 . C 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 17 1373 . C 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 17 1374 . C 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 17 1375 . T 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 17 1376 . A 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 17 1377 . A 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 17 1378 . G 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 17 1379 . C 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 17 1380 . C 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 17 1381 . C 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 17 1382 . G 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 17 1383 . C 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 17 1384 . C 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 17 1385 . A 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 17 1386 . C 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 17 1387 . C 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 17 1388 . C 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 17 1389 . G 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 17 1390 . G 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 17 1391 . A 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 17 1392 . G 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 17 1393 . A 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 17 1394 . C 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 17 1395 . A 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 17 1396 . G 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 17 1397 . C 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 17 1398 . G 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 17 1399 . G 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 17 1400 . A 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 17 1401 . T 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 17 1402 . T 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 17 1403 . T 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 17 1404 . C 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 17 1405 . C 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 17 1406 . T 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 17 1407 . T 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 17 1408 . A 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 17 1409 . G 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 17 1410 . T 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 17 1411 . T 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 17 1412 . A T, 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 17 1413 . C 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 17 1414 . T 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 17 1415 . T 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 17 1416 . A 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 17 1417 . C 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 17 1418 . T 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 17 1419 . A 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 17 1420 . T 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 17 1421 . G 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 17 1422 . C 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 17 1423 . T 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 17 1424 . C 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 17 1425 . C 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 17 1426 . T 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 17 1427 . T 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 17 1428 . G 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 17 1429 . G 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 17 1430 . C 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 17 1431 . C 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 17 1432 . A 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 17 1433 . T 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 17 1434 . T 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 17 1435 . T 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 17 1436 . C 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 17 1437 . T 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 17 1438 . C 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 17 1439 . T 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 17 1440 . A 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 17 1441 . G 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 17 1442 . G 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 17 1443 . T 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 17 1444 . A 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 17 1445 . T 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 17 1446 . T 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 17 1447 . G 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 17 1448 . G 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 17 1449 . T 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 17 1450 . A 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 17 1451 . T 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 17 1452 . A 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 17 1453 . T 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 17 1454 . T 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 17 1455 . G 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 17 1456 . T 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 17 1457 . G 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 17 1458 . T 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 17 1459 . C A, 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 17 1460 . T 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 17 1461 . G 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 17 1462 . C 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 17 1463 . T 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 17 1464 . G 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 17 1465 . T 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 17 1466 . G 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 17 1467 . A 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 17 1468 . A 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 17 1469 . C T, 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 17 1470 . T 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 17 1471 . G 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 17 1472 . T 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 17 1473 . C 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 17 1474 . C 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 17 1475 . T 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 17 1476 . T G, 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 17 1477 . G 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 17 1478 . G 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 17 1479 . C 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 17 1480 . C 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 17 1481 . T 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 17 1482 . G 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 17 1483 . T 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 17 1484 . T 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 17 1485 . T 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 17 1486 . G 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 17 1487 . G 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 17 1488 . T 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 17 1489 . G 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 17 1490 . A 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 17 1491 . C 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 17 1492 . G 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 17 1493 . G 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 17 1494 . G 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 17 1495 . T 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 17 1496 . G 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 17 1497 . A 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 17 1498 . G 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 17 1499 . G 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 17 1500 . A 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 17 1501 . G 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 17 1502 . C 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 17 1503 . A 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 17 1504 . G 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 17 1505 . G 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 17 1506 . G 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 17 1507 . A 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 17 1508 . C 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 17 1509 . A 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 17 1510 . G 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 17 1511 . A 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 17 1512 . A 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 17 1513 . G 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 17 1514 . G 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 17 1515 . G 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 17 1516 . T 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 17 1517 . C 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 17 1518 . C 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 17 1519 . T 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 17 1520 . G 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 17 1521 . C 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 17 1522 . G 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 17 1523 . T 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 17 1524 . G 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 17 1525 . C 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 17 1526 . C 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 17 1527 . C 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 17 1528 . T 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 17 1529 . G 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 17 1530 . C 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 17 1531 . C 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 17 1532 . T 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 17 1533 . T 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 17 1534 . C 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 17 1535 . A 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 17 1536 . C 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 17 1537 . A 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 17 1538 . A 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 17 1539 . G 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 17 1540 . C 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 17 1541 . C 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 17 1542 . C 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 17 1543 . C 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 17 1544 . T 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 17 1545 . G 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 17 1546 . G 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 17 1547 . A 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 17 1548 . A 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 17 1549 . G 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 17 1550 . G 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 17 1551 . A 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 17 1552 . A 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 17 1553 . A 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 17 1554 . G 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 17 1555 . T 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 17 1556 . T 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 17 1557 . G 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 17 1558 . T 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 17 1559 . T 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 17 1560 . T 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 17 1561 . T 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 17 1562 . G 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 17 1563 . G 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 17 1564 . G 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 17 1565 . A 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 17 1566 . T 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 17 1567 . C 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 17 1568 . T 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 17 1569 . C 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 17 1570 . T 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 17 1571 . G 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 17 1572 . C 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 17 1573 . A 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 17 1574 . C 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 17 1575 . C 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 17 1576 . C 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 17 1577 . T 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 17 1578 . C 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 17 1579 . A 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 17 1580 . G 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 17 1581 . C 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 17 1582 . C 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 17 1583 . T 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 17 1584 . G 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 17 1585 . G 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 17 1586 . A 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 17 1587 . C 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 17 1588 . A 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 17 1589 . A 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 17 1590 . C 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 17 1591 . T 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 17 1592 . T 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 17 1593 . G 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 17 1594 . T 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 17 1595 . G 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 17 1596 . C 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 17 1597 . C 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 17 1598 . C 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 17 1599 . A 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 17 1600 . T 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 17 1601 . C 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 17 1602 . T 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 17 1603 . G 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 17 1604 . G 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 17 1605 . T 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 17 1606 . G 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 17 1607 . A 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 17 1608 . C 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 17 1609 . C 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 17 1610 . C 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 17 1611 . C 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 17 1612 . T 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 17 1613 . C 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 17 1614 . A 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 17 1615 . C 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 17 1616 . T 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 17 1617 . C 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 17 1618 . A 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 17 1619 . G 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 17 1620 . C 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 17 1621 . C 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 17 1622 . A 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 17 1623 . C 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 17 1624 . C 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 17 1625 . A 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 17 1626 . G 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 17 1627 . A 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 17 1628 . C 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 17 1629 . T 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 17 1630 . T 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 17 1631 . C 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 17 1632 . C 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 17 1633 . A 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 17 1634 . C 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 17 1635 . G 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 17 1636 . A 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 17 1637 . C 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 17 1638 . A 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 17 1639 . G 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 17 1640 . G 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 17 1641 . C 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 17 1642 . T 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 17 1643 . C 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 17 1644 . C 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 17 1645 . A 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 17 1646 . G 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 17 1647 . C 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 17 1648 . C 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 17 1649 . T 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 17 1650 . C 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 17 1651 . G 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 17 1652 . G 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 17 1653 . C 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 17 1654 . A T, 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 17 1655 . C 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 17 1656 . C 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 17 1657 . T A, 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 17 1658 . T 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 17 1659 . C 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 17 1660 . A 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 17 1661 . G 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 17 1662 . C 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 17 1663 . C 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 17 1664 . A C, 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 17 1665 . T C, 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 17 1666 . G 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 17 1667 . G 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 17 1668 . A 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 17 1669 . C 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 17 1670 . A 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 17 1671 . G 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 17 1672 . T 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 17 1673 . T 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 17 1674 . C 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 17 1675 . C 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 17 1676 . G 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 17 1677 . C 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 17 1678 . C 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 17 1679 . A 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 17 1680 . G 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 17 1681 . C 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 17 1682 . G 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 17 1683 . T 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 17 1684 . T 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 17 1685 . G 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 17 1686 . C 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 17 1687 . C 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 17 1688 . C 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 17 1689 . T A, 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 17 1690 . C 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 17 1691 . T 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 17 1692 . G 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 17 1693 . T 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 17 1694 . T 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 17 1695 . C 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 17 1696 . T 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 17 1697 . G 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 17 1698 . C A, 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 17 1699 . T 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 17 1700 . G 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 17 1701 . T 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 17 1702 . T 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 17 1703 . T 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 17 1704 . T 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 17 1705 . C 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 17 1706 . T 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 17 1707 . C 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 17 1708 . T 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 17 1709 . A 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 17 1710 . C 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 17 1711 . C 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 17 1712 . A 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 17 1713 . G 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 17 1714 . A 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 17 1715 . A 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 17 1716 . G 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 17 1717 . T 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 17 1718 . G 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 17 1719 . C 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 17 1720 . C 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 17 1721 . C 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 17 1722 . T 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 17 1723 . T 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 17 1724 . C 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 17 1725 . C G, 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 17 1726 . C 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 17 1727 . T 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 17 1728 . C 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 17 1729 . C 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 17 1730 . T 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 17 1731 . C 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 17 1732 . A 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 17 1733 . C 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 17 1734 . C 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 17 1735 . T 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 17 1736 . G 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 17 1737 . A 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 17 1738 . C 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 17 1739 . C 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 17 1740 . A 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 17 1741 . C 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 17 1742 . T 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 17 1743 . C 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 17 1744 . T 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 17 1745 . G 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 17 1746 . G 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 17 1747 . G 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 17 1748 . G 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 17 1749 . A 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 17 1750 . A 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 17 1751 . A 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 17 1752 . T 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 17 1753 . C 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 17 1754 . C 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 17 1755 . C 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 17 1756 . T 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 17 1757 . C 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 17 1758 . A 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 17 1759 . G 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 17 1760 . C 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 17 1761 . A 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 17 1762 . C 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 17 1763 . C 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 17 1764 . C 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 17 1765 . T 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 17 1766 . C 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 17 1767 . C 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 17 1768 . C 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 17 1769 . T 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 17 1770 . G 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 17 1771 . A 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 17 1772 . G 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 17 1773 . C 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 17 1774 . A 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 17 1775 . T 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 17 1776 . A 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 17 1777 . C 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 17 1778 . C 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 17 1779 . C 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 17 1780 . T 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 17 1781 . A 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 17 1782 . C 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 17 1783 . T 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 17 1784 . C 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 17 1785 . T 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 17 1786 . G 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 17 1787 . G 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 17 1788 . C 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 17 1789 . A 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 17 1790 . C 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 17 1791 . A 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 17 1792 . A 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 17 1793 . G 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 17 1794 . C 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 17 1795 . C 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 17 1796 . C 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 17 1797 . A 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 17 1798 . C 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 17 1799 . C 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 17 1800 . C 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 17 1801 . T 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 17 1802 . G 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 17 1803 . C 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 17 1804 . A 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 17 1805 . A 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 17 1806 . A 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 17 1807 . G 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 17 1808 . C 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 17 1809 . C 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 17 1810 . C 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 17 1811 . C 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 17 1812 . T 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 17 1813 . G 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 17 1814 . A 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 17 1815 . G 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 17 1816 . G 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 17 1817 . C 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 17 1818 . C 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 17 1819 . C 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 17 1820 . G 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 17 1821 . C 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 17 1822 . C 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 17 1823 . C 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 17 1824 . T 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 17 1825 . G 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 17 1826 . T 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 17 1827 . G 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 17 1828 . G 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 17 1829 . C 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 17 1830 . G 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 17 1831 . T 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 17 1832 . C 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 17 1833 . T 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 17 1834 . C 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 17 1835 . T 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 17 1836 . C 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 17 1837 . C 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 17 1838 . C 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 17 1839 . T 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 17 1840 . C 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 17 1841 . C 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 17 1842 . C 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 17 1843 . T 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 17 1844 . T 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 17 1845 . G 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 17 1846 . C 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 17 1847 . T 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 17 1848 . G 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 17 1849 . T 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 17 1850 . C 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 17 1851 . A 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 17 1852 . G 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 17 1853 . G 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 17 1854 . A 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 17 1855 . C 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 17 1856 . A 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 17 1857 . G 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 17 1858 . T 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 17 1859 . G 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 17 1860 . G 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 17 1861 . T 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 17 1862 . C 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 17 1863 . C 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 17 1864 . T 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 17 1865 . G 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 17 1866 . G 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 17 1867 . C 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 17 1868 . C 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 17 1869 . A T, 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 17 1870 . C 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 17 1871 . C 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 17 1872 . G 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 17 1873 . G 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 17 1874 . G 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 17 1875 . G 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 17 1876 . C 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 17 1877 . T 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 17 1878 . C 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 17 1879 . A 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 17 1880 . C 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 17 1881 . G 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 17 1882 . G 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 17 1883 . A 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 17 1884 . G 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 17 1885 . C 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 17 1886 . C 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 17 1887 . G 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 17 1888 . C 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 17 1889 . C 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 17 1890 . C 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 17 1891 . T 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 17 1892 . G 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 17 1893 . T 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 17 1894 . G 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 17 1895 . C 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 17 1896 . C 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 17 1897 . G 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 17 1898 . T 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 17 1899 . G 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 17 1900 . T 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 17 1901 . A 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 17 1902 . C 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 17 1903 . C 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 17 1904 . T 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 17 1905 . C 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 17 1906 . T 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 17 1907 . G 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 17 1908 . A 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 17 1909 . G 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 17 1910 . C 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 17 1911 . C 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 17 1912 . C 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 17 1913 . T 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 17 1914 . C 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 17 1915 . T C, 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 17 1916 . G T, 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 17 1917 . C 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 17 1918 . A 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 17 1919 . C 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 17 1920 . A T, 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 17 1921 . G 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 17 1922 . T 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 17 1923 . G 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 17 1924 . C 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 17 1925 . C 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 17 1926 . T 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 17 1927 . T 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 17 1928 . C 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 17 1929 . T 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 17 1930 . G 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 17 1931 . C 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 17 1932 . T 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 17 1933 . T 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 17 1934 . G 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 17 1935 . C 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 17 1936 . C 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 17 1937 . T 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 17 1938 . G 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 17 1939 . T 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 17 1940 . G 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 17 1941 . G 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 17 1942 . C 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 17 1943 . T 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 17 1944 . T 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 17 1945 . T 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 17 1946 . G 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 17 1947 . A 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 17 1948 . G C, 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 17 1949 . A 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 17 1950 . A 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 17 1951 . G 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 17 1952 . A 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 17 1953 . A 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 17 1954 . A C, 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 17 1955 . C 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 17 1956 . C 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 17 1957 . C 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 17 1958 . C 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 17 1959 . T 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 17 1960 . T 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 17 1961 . C 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 17 1962 . T 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 17 1963 . G 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 17 1964 . G 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 17 1965 . T 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 17 1966 . T 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 17 1967 . A 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 17 1968 . T 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 17 1969 . A 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 17 1970 . C 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 17 1971 . A 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 17 1972 . T 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 17 1973 . A 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 17 1974 . A 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 17 1975 . G 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 17 1976 . A 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 17 1977 . C 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 17 1978 . A 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 17 1979 . G 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 17 1980 . C 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 17 1981 . C 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 17 1982 . A 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 17 1983 . G 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 17 1984 . A 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 17 1985 . G 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 17 1986 . A 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 17 1987 . A 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 17 1988 . G 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 17 1989 . G 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 17 1990 . G T, 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 17 1991 . A 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 17 1992 . G 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 17 1993 . T 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 17 1994 . T 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 17 1995 . G 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 17 1996 . C 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 17 1997 . C 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 17 1998 . C 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 17 1999 . A 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 17 2000 . G 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 17 2001 . G 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 17 2002 . G 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 17 2003 . T 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 17 2004 . G 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 17 2005 . G 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 17 2006 . C 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 17 2007 . A 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 17 2008 . C 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 17 2009 . A 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 17 2010 . G 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 17 2011 . C 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 17 2012 . A 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 17 2013 . C 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 17 2014 . G 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 17 2015 . T 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 17 2016 . T 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 17 2017 . G 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 17 2018 . C 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 17 2019 . T 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 17 2020 . G 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 17 2021 . C 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 17 2022 . C 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 17 2023 . A 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 17 2024 . G 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 17 2025 . T 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 17 2026 . T 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 17 2027 . A 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 17 2028 . C 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 17 2029 . T 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 17 2030 . G 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 17 2031 . C 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 17 2032 . C 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 17 2033 . A 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 17 2034 . T 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 17 2035 . T 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 17 2036 . T 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 17 2037 . T 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 17 2038 . C 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 17 2039 . A 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 17 2040 . C 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 17 2041 . G A, 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 17 2042 . G 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 17 2043 . G 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 17 2044 . C 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 17 2045 . A 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 17 2046 . T 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 17 2047 . G 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 17 2048 . A 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 17 2049 . A 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 17 2050 . A 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 17 2051 . T 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 17 2052 . G 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 17 2053 . G T, 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 17 2054 . A 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 17 2055 . G 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 17 2056 . A 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 17 2057 . T 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 17 2058 . A 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 17 2059 . A 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 17 2060 . C 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 17 2061 . A 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 17 2062 . A 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 17 2063 . C 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 17 2064 . A 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 17 2065 . G 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 17 2066 . G 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 17 2067 . A 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 17 2068 . G 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 17 2069 . C 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 17 2070 . G 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 17 2071 . A 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 17 2072 . C 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 17 2073 . C 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 17 2074 . G 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 17 2075 . C 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 17 2076 . A 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 17 2077 . C 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 17 2078 . A 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 17 2079 . G 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 17 2080 . G 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 17 2081 . C 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 17 2082 . T 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 17 2083 . G 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 17 2084 . C 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 17 2085 . T 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 17 2086 . G 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 17 2087 . A 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 17 2088 . G 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 17 2089 . C 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 17 2090 . G 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 17 2091 . C 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 17 2092 . G 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 17 2093 . T G, 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 17 2094 . C 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 17 2095 . A 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 17 2096 . C 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 17 2097 . A 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 17 2098 . C 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 17 2099 . G 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 17 2100 . C 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 17 2101 . A 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 17 2102 . G 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 17 2103 . C 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 17 2104 . C 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 17 2105 . A 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 17 2106 . T 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 17 2107 . C 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 17 2108 . G 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 17 2109 . C 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 17 2110 . G 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 17 2111 . C 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 17 2112 . A 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 17 2113 . G 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 17 2114 . C 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 17 2115 . T 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 17 2116 . C 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 17 2117 . A 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 17 2118 . G 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 17 2119 . G 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 17 2120 . G 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 17 2121 . A 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 17 2122 . T 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 17 2123 . A 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 17 2124 . T 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 17 2125 . T 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 17 2126 . A 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 17 2127 . C 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 17 2128 . G 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 17 2129 . T 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 17 2130 . G 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 17 2131 . T 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 17 2132 . A 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 17 2133 . A 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 17 2134 . C 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 17 2135 . T 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 17 2136 . C 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 17 2137 . G 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 17 2138 . A 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 17 2139 . C 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 17 2140 . A 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 17 2141 . T 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 17 2142 . G 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 17 2143 . T 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 17 2144 . C 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 17 2145 . A 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 17 2146 . G 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 17 2147 . C 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 17 2148 . G 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 17 2149 . A 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 17 2150 . T 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 17 2151 . T 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 17 2152 . G 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 17 2153 . T 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 17 2154 . C 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 17 2155 . A 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 17 2156 . C 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 17 2157 . A 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 17 2158 . G 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 17 2159 . G 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 17 2160 . C 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 17 2161 . A 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 17 2162 . C 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 17 2163 . T 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 17 2164 . G 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 17 2165 . C 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 17 2166 . T 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 17 2167 . A 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 17 2168 . C 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 17 2169 . T 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 17 2170 . C 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 17 2171 . C 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 17 2172 . T 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 17 2173 . G 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 17 2174 . G 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 17 2175 . G 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 17 2176 . G 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 17 2177 . T 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 17 2178 . T 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 17 2179 . T 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 17 2180 . T 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 17 2181 . C 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 17 2182 . C 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 17 2183 . A 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 17 2184 . T 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 17 2185 . C 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 17 2186 . A 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 17 2187 . A 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 17 2188 . A 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 17 2189 . C 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 17 2190 . C 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 17 2191 . C 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 17 2192 . T 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 17 2193 . C 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 17 2194 . A 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 17 2195 . A 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 17 2196 . G 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 17 2197 . A 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 17 2198 . G 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 17 2199 . C 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 17 2200 . T 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 17 2201 . G 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 17 2202 . G 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 17 2203 . G 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 17 2204 . C 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 17 2205 . C 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 17 2206 . T 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 17 2207 . G 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 17 2208 . G 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 17 2209 . G 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 17 2210 . G C, 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 17 2211 . T 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 17 2212 . C 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 17 2213 . A 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 17 2214 . A 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 17 2215 . C 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 17 2216 . T 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 17 2217 . T 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 17 2218 . C 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 17 2219 . C 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 17 2220 . G A, 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 17 2221 . G 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 17 2222 . C 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 17 2223 . C 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 17 2224 . T 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 17 2225 . G 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 17 2226 . G 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 17 2227 . G 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 17 2228 . G C, 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 17 2229 . A 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 17 2230 . A 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 17 2231 . A 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 17 2232 . C 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 17 2233 . T 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 17 2234 . G 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 17 2235 . G 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 17 2236 . G 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 17 2237 . G 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 17 2238 . C 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 17 2239 . A 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 17 2240 . A 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 17 2241 . G 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 17 2242 . T 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 17 2243 . A 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 17 2244 . T 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 17 2245 . C 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 17 2246 . A 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 17 2247 . C 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 17 2248 . C 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 17 2249 . A 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 17 2250 . G 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 17 2251 . A 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 17 2252 . G 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 17 2253 . A 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 17 2254 . T 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 17 2255 . G 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 17 2256 . A 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 17 2257 . G 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 17 2258 . C 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 17 2259 . T 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 17 2260 . T 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 17 2261 . T 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 17 2262 . A 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 17 2263 . T 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 17 2264 . A 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 17 2265 . A 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 17 2266 . A 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 17 2267 . A 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 17 2268 . A 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 17 2269 . T 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 17 2270 . A 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 17 2271 . A 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 17 2272 . T 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 17 2273 . G 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 17 2274 . G 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 17 2275 . T 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 17 2276 . G 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 17 2277 . C 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 17 2278 . T 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 17 2279 . A 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 17 2280 . G 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 17 2281 . C 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 17 2282 . T 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 17 2283 . G 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 17 2284 . G 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 17 2285 . G 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 17 2286 . C 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 17 2287 . A 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 17 2288 . T 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 17 2289 . G 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 17 2290 . G 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 17 2291 . T 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 17 2292 . G 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 17 2293 . G 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 17 2294 . C 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 17 2295 . T 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 17 2296 . T 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 17 2297 . G 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 17 2298 . C 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 17 2299 . A 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 17 2300 . C 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 17 2301 . C 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 17 2302 . T 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 17 2303 . G 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 17 2304 . T 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 17 2305 . A 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 17 2306 . A 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 17 2307 . T 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 17 2308 . C 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 17 2309 . C A, 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 17 2310 . C 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 17 2311 . A 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 17 2312 . G 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 17 2313 . C 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 17 2314 . A 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 17 2315 . C 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 17 2316 . T 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 17 2317 . T 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 17 2318 . T 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 17 2319 . G 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 17 2320 . G 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 17 2321 . G 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 17 2322 . A 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 17 2323 . G 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 17 2324 . G 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 17 2325 . C 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 17 2326 . C 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 17 2327 . G 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 17 2328 . A 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 17 2329 . G 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 17 2330 . C 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 17 2331 . T 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 17 2332 . A 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 17 2333 . G 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 17 2334 . G 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 17 2335 . A 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 17 2336 . G 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 17 2337 . G 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 17 2338 . A 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 17 2339 . T 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 17 2340 . C 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 17 2341 . G 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 17 2342 . T 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 17 2343 . T 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 17 2344 . T 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 17 2345 . G 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 17 2346 . A 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 17 2347 . G 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 17 2348 . T 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 17 2349 . C 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 17 2350 . C 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 17 2351 . A 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 17 2352 . G 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 17 2353 . C 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 17 2354 . A 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 17 2355 . G 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 17 2356 . T 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 17 2357 . T 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 17 2358 . T 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 17 2359 . G 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 17 2360 . A 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 17 2361 . G 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 17 2362 . A 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 17 2363 . C 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 17 2364 . C 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 17 2365 . A 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 17 2366 . G 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 17 2367 . C 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 17 2368 . C 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 17 2369 . T 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 17 2370 . G 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 17 2371 . G 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 17 2372 . C 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 17 2373 . C 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 17 2374 . A 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 17 2375 . A 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 17 2376 . T 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 17 2377 . A 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 17 2378 . C 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 17 2379 . G 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 17 2380 . G 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 17 2381 . C 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 17 2382 . A 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 17 2383 . A 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 17 2384 . A 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 17 2385 . A 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 17 2386 . C 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 17 2387 . C 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 17 2388 . C 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 17 2389 . A 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 17 2390 . G 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 17 2391 . T 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 17 2392 . C 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 17 2393 . T 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 17 2394 . C 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 17 2395 . T 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 17 2396 . A 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 17 2397 . C 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 17 2398 . A 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 17 2399 . A 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 17 2400 . A 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 17 2401 . A 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 17 2402 . A 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 17 2403 . A 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 17 2404 . T 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 17 2405 . A 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 17 2406 . C 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 17 2407 . A 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 17 2408 . A 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 17 2409 . A 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 17 2410 . A 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 17 2411 . A 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 17 2412 . A 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 17 2413 . C 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 17 2414 . A 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 17 2415 . A 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 17 2416 . C 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 17 2417 . T 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 17 2418 . A 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 17 2419 . G 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 17 2420 . C 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 17 2421 . C 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 17 2422 . A 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 17 2423 . G 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 17 2424 . G 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 17 2425 . C 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 17 2426 . G 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 17 2427 . T 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 17 2428 . G 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 17 2429 . G 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 17 2430 . T A, 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 17 2431 . G 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 17 2432 . G 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 17 2433 . T 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 17 2434 . G 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 17 2435 . C 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 17 2436 . A 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 17 2437 . C 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 17 2438 . A 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 17 2439 . C 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 17 2440 . C 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 17 2441 . T 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 17 2442 . G 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 17 2443 . T 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 17 2444 . A 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 17 2445 . G 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 17 2446 . T 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 17 2447 . C 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 17 2448 . C 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 17 2449 . C 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 17 2450 . A 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 17 2451 . G 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 17 2452 . C 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 17 2453 . T 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 17 2454 . A 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 17 2455 . C 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 17 2456 . T 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 17 2457 . C 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 17 2458 . A 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 17 2459 . G T, 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 17 2460 . G 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 17 2461 . A G, 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 17 2462 . G 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 17 2463 . G T, 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 17 2464 . C 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 17 2465 . T 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 17 2466 . G 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 17 2467 . A 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 17 2468 . G 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 17 2469 . G 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 17 2470 . G 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 17 2471 . G 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 17 2472 . G 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 17 2473 . A 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 17 2474 . A 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 17 2475 . G 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 17 2476 . G 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 17 2477 . A 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 17 2478 . C 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 17 2479 . T 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 17 2480 . G 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 17 2481 . C 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 17 2482 . T 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 17 2483 . T 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 17 2484 . G 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 17 2485 . A T, 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 17 2486 . G 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 17 2487 . C 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 17 2488 . C 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 17 2489 . C 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 17 2490 . A 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 17 2491 . G 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 17 2492 . G A, 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 17 2493 . A G, 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 17 2494 . G 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 17 2495 . T 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 17 2496 . T 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 17 2497 . T 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 17 2498 . G 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 17 2499 . A 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 17 2500 . G 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 17 2501 . G 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 17 2502 . C 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 17 2503 . T 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 17 2504 . G 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 17 2505 . C 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 17 2506 . T 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 17 2507 . G 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 17 2508 . T 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 17 2509 . G T, 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 17 2510 . A 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 17 2511 . G 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 17 2512 . C 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 17 2513 . T 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 17 2514 . G 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 17 2515 . T 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 17 2516 . G 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 17 2517 . A 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 17 2518 . T 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 17 2519 . C 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 17 2520 . G 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 17 2521 . C 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 17 2522 . A 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 17 2523 . T 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 17 2524 . C 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 17 2525 . A C, 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 17 2526 . C 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 17 2527 . T 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 17 2528 . G 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 17 2529 . C 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 17 2530 . A 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 17 2531 . T 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 17 2532 . T 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 17 2533 . C 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 17 2534 . C 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 17 2535 . A 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 17 2536 . G 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 17 2537 . C 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 17 2538 . C 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 17 2539 . C 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 17 2540 . G 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 17 2541 . G 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 17 2542 . T 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 17 2543 . G 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 17 2544 . A 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 17 2545 . C 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 17 2546 . A 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 17 2547 . G 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 17 2548 . A 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 17 2549 . G 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 17 2550 . T 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 17 2551 . G 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 17 2552 . A 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 17 2553 . G 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 17 2554 . T 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 17 2555 . C 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 17 2556 . A 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 17 2557 . C 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 17 2558 . T 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 17 2559 . G 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 17 2560 . T 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 17 2561 . C 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 17 2562 . T 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 17 2563 . C 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 17 2564 . A G, 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 17 2565 . A 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 17 2566 . A 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 17 2567 . A 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 17 2568 . A 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 17 2569 . A 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 17 2570 . G 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 17 2571 . A 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 17 2572 . A 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 17 2573 . A 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 17 2574 . G 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 17 2575 . G 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 17 2576 . A 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 17 2577 . A 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 17 2578 . G 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 17 2579 . A 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 17 2580 . A 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 17 2581 . A 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 17 2582 . T 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 17 2583 . A 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 17 2584 . A 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 17 2585 . A 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 17 2586 . G 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 17 2587 . A 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 17 2588 . A 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 17 2589 . A 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 17 2590 . A 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 17 2591 . C 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 17 2592 . A 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 17 2593 . A 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 17 2594 . A 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 17 2595 . T 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 17 2596 . A 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 17 2597 . A 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 17 2598 . A 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 17 2599 . A 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 17 2600 . A 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 17 2601 . T 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 17 2602 . A 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 17 2603 . A 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 17 2604 . T 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 17 2605 . A 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 17 2606 . G 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 17 2607 . T 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 17 2608 . G 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 17 2609 . C 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 17 2610 . A 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 17 2611 . G 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 17 2612 . A 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 17 2613 . C 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 17 2614 . A 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 17 2615 . A 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 17 2616 . A 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 17 2617 . A 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 17 2618 . G 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 17 2619 . G 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 17 2620 . C 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 17 2621 . C 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 17 2622 . T 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 17 2623 . T 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 17 2624 . G 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 17 2625 . A 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 17 2626 . C 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 17 2627 . C 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 17 2628 . C 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 17 2629 . A 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 17 2630 . T 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 17 2631 . C 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 17 2632 . T 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 17 2633 . A 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 17 2634 . G 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 17 2635 . C 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 17 2636 . T 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 17 2637 . T 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 17 2638 . T 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 17 2639 . G 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 17 2640 . G 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 17 2641 . C 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 17 2642 . C 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 17 2643 . C 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 17 2644 . T 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 17 2645 . C 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 17 2646 . A 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 17 2647 . G 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 17 2648 . C 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 17 2649 . A 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 17 2650 . T 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 17 2651 . C 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 17 2652 . A 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 17 2653 . A 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 17 2654 . C 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 17 2655 . C 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 17 2656 . G 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 17 2657 . C 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 17 2658 . T 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 17 2659 . A 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 17 2660 . G 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 17 2661 . A 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 17 2662 . T 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 17 2663 . A 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 17 2664 . C 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 17 2665 . G 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 17 2666 . T 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 17 2667 . C 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 17 2668 . C 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 17 2669 . C 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 17 2670 . T 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 17 2671 . C 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 17 2672 . C 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 17 2673 . C 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 17 2674 . T 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 17 2675 . T 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 17 2676 . T 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 17 2677 . C 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 17 2678 . T 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 17 2679 . T 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 17 2680 . C 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 17 2681 . T 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 17 2682 . G 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 17 2683 . G 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 17 2684 . G 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 17 2685 . G 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 17 2686 . C 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 17 2687 . A 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 17 2688 . C 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 17 2689 . A 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 17 2690 . G 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 17 2691 . G 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 17 2692 . T 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 17 2693 . C 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 17 2694 . A 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 17 2695 . C 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 17 2696 . A 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 17 2697 . C 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 17 2698 . T 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 17 2699 . C 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 17 2700 . T 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 17 2701 . C 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 17 2702 . T 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 17 2703 . T 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 17 2704 . C 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 17 2705 . C 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 17 2706 . A 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 17 2707 . G 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 17 2708 . G 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 17 2709 . T 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 17 2710 . C 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 17 2711 . T 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 17 2712 . A 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 17 2713 . G T, 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 17 2714 . G 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 17 2715 . A 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 17 2716 . T 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 17 2717 . G 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 17 2718 . C 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 17 2719 . A 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 17 2720 . G 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 17 2721 . C 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 17 2722 . T 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 17 2723 . G 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 17 2724 . A 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 17 2725 . G 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 17 2726 . G 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 17 2727 . G 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 17 2728 . G 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 17 2729 . T 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 17 2730 . G 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 17 2731 . C 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 17 2732 . C 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 17 2733 . C A, 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 17 2734 . C 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 17 2735 . T 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 17 2736 . C 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 17 2737 . T 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 17 2738 . T 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 17 2739 . A 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 17 2740 . C 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 17 2741 . C 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 17 2742 . A 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 17 2743 . T 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 17 2744 . C 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 17 2745 . T 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 17 2746 . A 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 17 2747 . A 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 17 2748 . T 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 17 2749 . C 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 17 2750 . T 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 17 2751 . G 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 17 2752 . T 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 17 2753 . G 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 17 2754 . C 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 17 2755 . C 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 17 2756 . C 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 17 2757 . T 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 17 2758 . T 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 17 2759 . A 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 17 2760 . T 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 17 2761 . T 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 17 2762 . T 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 17 2763 . C A, 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 17 2764 . C 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 17 2765 . T 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 17 2766 . C 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 17 2767 . T 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 17 2768 . G 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 17 2769 . C 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 17 2770 . T 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 17 2771 . T 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 17 2772 . T 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 17 2773 . A 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 17 2774 . G 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 17 2775 . T 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 17 2776 . G 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 17 2777 . A 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 17 2778 . G 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 17 2779 . G 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 17 2780 . A 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 17 2781 . A 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 17 2782 . G 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 17 2783 . A 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 17 2784 . G 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 17 2785 . G 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 17 2786 . C 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 17 2787 . C 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 17 2788 . C 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 17 2789 . C 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 17 2790 . T 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 17 2791 . G 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 17 2792 . G 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 17 2793 . T 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 17 2794 . C 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 17 2795 . C 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 17 2796 . A 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 17 2797 . T 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 17 2798 . G 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 17 2799 . A 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 17 2800 . A 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 17 2801 . G 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 17 2802 . G 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 17 2803 . G 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 17 2804 . G 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 17 2805 . C 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 17 2806 . C 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 17 2807 . T 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 17 2808 . T 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 17 2809 . T 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 17 2810 . C 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 17 2811 . A 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 17 2812 . G 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 17 2813 . A 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 17 2814 . G 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 17 2815 . A 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 17 2816 . C 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 17 2817 . G 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 17 2818 . G 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 17 2819 . G 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 17 2820 . G 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 17 2821 . A 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 17 2822 . C 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 17 2823 . C 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 17 2824 . C 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 17 2825 . C 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 17 2826 . T 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 17 2827 . G 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 17 2828 . A 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 17 2829 . G 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 17 2830 . G 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 17 2831 . A 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 17 2832 . G 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 17 2833 . C 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 17 2834 . C 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 17 2835 . C 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 17 2836 . C 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 17 2837 . G 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 17 2838 . A 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 17 2839 . G 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 17 2840 . C 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 17 2841 . A 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 17 2842 . G 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 17 2843 . C 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 17 2844 . A 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 17 2845 . G 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 17 2846 . C 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 17 2847 . C 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 17 2848 . G 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 17 2849 . T 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 17 2850 . C 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 17 2851 . G 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 17 2852 . T 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 17 2853 . G 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 17 2854 . T 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 17 2855 . C 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 17 2856 . T 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 17 2857 . C 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 17 2858 . A 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 17 2859 . C 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 17 2860 . C 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 17 2861 . C 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 17 2862 . A 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 17 2863 . G 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 17 2864 . G 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 17 2865 . G 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 17 2866 . T 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 17 2867 . G 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 17 2868 . T 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 17 2869 . C 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 17 2870 . T 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 17 2871 . G 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 17 2872 . A 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 17 2873 . A 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 17 2874 . A 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 17 2875 . C 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 17 2876 . A 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 17 2877 . G 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 17 2878 . A 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 17 2879 . T 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 17 2880 . G 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 17 2881 . T 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 17 2882 . G 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 17 2883 . G 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 17 2884 . A 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 17 2885 . G 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 17 2886 . G A, 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 17 2887 . T 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 17 2888 . C 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 17 2889 . T 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 17 2890 . C 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 17 2891 . G 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 17 2892 . G 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 17 2893 . G 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 17 2894 . T 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 17 2895 . G 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 17 2896 . A 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 17 2897 . G 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 17 2898 . G 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 17 2899 . C 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 17 2900 . G 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 17 2901 . T 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 17 2902 . G 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 17 2903 . G 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 17 2904 . C 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 17 2905 . T 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 17 2906 . C 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 17 2907 . A 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 17 2908 . G 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 17 2909 . A 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 17 2910 . T 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 17 2911 . A 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 17 2912 . C 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 17 2913 . A 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 17 2914 . G 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 17 2915 . G 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 17 2916 . G 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 17 2917 . A 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 17 2918 . G 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 17 2919 . T 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 17 2920 . G 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 17 2921 . G 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 17 2922 . C 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 17 2923 . C 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 17 2924 . C 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 17 2925 . A 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 17 2926 . C 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 17 2927 . A 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 17 2928 . G 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 17 2929 . C 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 17 2930 . T 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 17 2931 . C 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 17 2932 . G 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 17 2933 . G 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 17 2934 . C 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 17 2935 . C 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 17 2936 . T 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 17 2937 . G 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 17 2938 . T 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 17 2939 . C 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 17 2940 . T 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 17 2941 . T 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 17 2942 . T 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 17 2943 . G 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 17 2944 . A 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 17 2945 . A 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 17 2946 . A 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 17 2947 . G 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 17 2948 . G 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 17 2949 . C 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 17 2950 . C 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 17 2951 . A 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 17 2952 . C 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 17 2953 . G 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 17 2954 . T 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 17 2955 . G 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 17 2956 . A 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 17 2957 . C 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 17 2958 . C 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 17 2959 . T 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 17 2960 . G 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 17 2961 . G 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 17 2962 . C 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 17 2963 . C 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 17 2964 . C 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 17 2965 . A 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 17 2966 . C 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 17 2967 . G 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 17 2968 . G 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 17 2969 . C 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 17 2970 . T 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 17 2971 . G 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 17 2972 . G 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 17 2973 . C 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 17 2974 . A 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 17 2975 . G 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 17 2976 . G 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 17 2977 . T 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 17 2978 . G 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 17 2979 . G 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 17 2980 . G 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 17 2981 . A 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 17 2982 . C 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 17 2983 . C 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 17 2984 . C 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 17 2985 . A 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 17 2986 . G 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 17 2987 . C 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 17 2988 . T 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 17 2989 . G 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 17 2990 . C 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 17 2991 . A 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 17 2992 . G 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 17 2993 . G 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 17 2994 . G 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 17 2995 . G 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 17 2996 . T 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 17 2997 . C 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 17 2998 . C 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 17 2999 . A 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 17 3000 . G 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 17 3001 . C 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 17 3002 . A 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 17 3003 . G 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 17 3004 . C 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 17 3005 . A 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 17 3006 . C 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 17 3007 . C 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 17 3008 . C 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 17 3009 . A 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 17 3010 . C 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 17 3011 . A 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 17 3012 . G 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 17 3013 . C 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 17 3014 . A 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 17 3015 . G 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 17 3016 . C 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 17 3017 . C A, 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 17 3018 . A 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 17 3019 . C 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 17 3020 . C 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 17 3021 . T 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 17 3022 . G 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 17 3023 . T G, 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 17 3024 . G 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 17 3025 . G 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 17 3026 . C 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 17 3027 . A 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 17 3028 . G 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 17 3029 . G 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 17 3030 . G 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 17 3031 . A 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 17 3032 . G 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 17 3033 . G 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 17 3034 . A 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 17 3035 . G 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 17 3036 . C 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 17 3037 . T 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 17 3038 . T 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 17 3039 . G 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 17 3040 . T 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 17 3041 . G 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 17 3042 . G 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 17 3043 . T 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 17 3044 . A C, 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 17 3045 . C 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 17 3046 . A 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 17 3047 . G 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 17 3048 . T 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 17 3049 . G 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 17 3050 . G 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 17 3051 . A 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 17 3052 . C 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 17 3053 . A 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 17 3054 . G 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 17 3055 . G 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 17 3056 . C 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 17 3057 . C 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 17 3058 . C 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 17 3059 . T G, 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 17 3060 . G 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 17 3061 . C 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 17 3062 . C 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 17 3063 . C 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 17 3064 . A 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 17 3065 . G 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 17 3066 . A 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 17 3067 . T 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 17 3068 . G 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 17 3069 . G 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 17 3070 . C 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 17 3071 . C 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 17 3072 . C 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 17 3073 . C 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 17 3074 . C 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 17 3075 . C 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 17 3076 . G 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 17 3077 . C 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 17 3078 . C 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 17 3079 . T 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 17 3080 . G 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 17 3081 . C 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 17 3082 . C 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 17 3083 . T C, 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 17 3084 . G 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 17 3085 . T 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 17 3086 . G 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 17 3087 . G 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 17 3088 . A 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 17 3089 . A 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 17 3090 . G 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 17 3091 . T 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 17 3092 . T 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 17 3093 . G 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 17 3094 . A 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 17 3095 . C 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 17 3096 . C 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 17 3097 . A 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 17 3098 . G 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 17 3099 . A 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 17 3100 . C 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 17 3101 . C 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 17 3102 . A 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 17 3103 . T 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 17 3104 . C T, 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 17 3105 . T 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 17 3106 . G 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 17 3107 . T 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 17 3108 . C 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 17 3109 . A 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 17 3110 . C 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 17 3111 . A 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 17 3112 . G 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 17 3113 . C 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 17 3114 . A 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 17 3115 . G 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 17 3116 . G 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 17 3117 . T 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 17 3118 . A 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 17 3119 . A 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 17 3120 . G 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 17 3121 . A 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 17 3122 . C 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 17 3123 . T 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 17 3124 . C 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 17 3125 . T 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 17 3126 . G 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 17 3127 . C 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 17 3128 . T 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 17 3129 . T 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 17 3130 . T 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 17 3131 . C 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 17 3132 . T 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 17 3133 . G 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 17 3134 . G 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 17 3135 . G 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 17 3136 . C 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 17 3137 . A 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 17 3138 . A 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 17 3139 . C 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 17 3140 . C 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 17 3141 . C 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 17 3142 . A 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 17 3143 . G 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 17 3144 . C 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 17 3145 . A 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 17 3146 . G 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 17 3147 . G 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 17 3148 . T 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 17 3149 . G 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 17 3150 . A 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 17 3151 . C 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 17 3152 . C 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 17 3153 . C 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 17 3154 . T 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 17 3155 . G 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 17 3156 . G 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 17 3157 . A 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 17 3158 . A 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 17 3159 . T 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 17 3160 . T 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 17 3161 . C 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 17 3162 . C 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 17 3163 . T A, 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 17 3164 . G 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 17 3165 . T 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 17 3166 . C 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 17 3167 . C 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 17 3168 . A 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 17 3169 . T 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 17 3170 . C 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 17 3171 . T 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 17 3172 . G 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 17 3173 . G 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 17 3174 . C 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 17 3175 . A 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 17 3176 . G 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 17 3177 . G 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 17 3178 . T 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 17 3179 . G 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 17 3180 . G 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 17 3181 . G 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 17 3182 . C 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 17 3183 . A 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 17 3184 . T 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 17 3185 . T 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 17 3186 . G 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 17 3187 . A 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 17 3188 . A 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 17 3189 . A 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 17 3190 . C 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 17 3191 . T 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 17 3192 . G 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 17 3193 . G 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 17 3194 . T C, 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 17 3195 . T 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 17 3196 . T 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 17 3197 . A 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 17 3198 . A 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 17 3199 . A 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 17 3200 . A 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 17 3201 . A 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 17 3202 . T 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 17 3203 . G A, 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 17 3204 . T 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 17 3205 . C 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 17 3206 . A 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 17 3207 . C 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 17 3208 . A 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 17 3209 . C 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 17 3210 . C 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 17 3211 . A 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 17 3212 . T 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 17 3213 . A 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 17 3214 . G 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 17 3215 . G 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 17 3216 . C 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 17 3217 . C 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 17 3218 . G C, 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 17 3219 . G A, 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 17 3220 . G 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 17 3221 . C 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 17 3222 . A 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 17 3223 . C 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 17 3224 . A 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 17 3225 . G 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 17 3226 . T 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 17 3227 . G 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 17 3228 . G 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 17 3229 . C 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 17 3230 . T 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 17 3231 . C 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 17 3232 . A 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 17 3233 . C 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 17 3234 . G T, 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 17 3235 . C 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 17 3236 . C 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 17 3237 . T 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 17 3238 . G 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 17 3239 . T 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 17 3240 . A 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 17 3241 . A 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 17 3242 . T 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 17 3243 . C 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 17 3244 . C 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 17 3245 . C 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 17 3246 . A 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 17 3247 . G 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 17 3248 . C 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 17 3249 . C 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 17 3250 . C 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 17 3251 . T 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 17 3252 . T 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 17 3253 . T 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 17 3254 . G 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 17 3255 . G 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 17 3256 . G 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 17 3257 . A 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 17 3258 . G 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 17 3259 . G 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 17 3260 . C 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 17 3261 . C 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 17 3262 . A 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 17 3263 . G 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 17 3264 . G 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 17 3265 . G 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 17 3266 . T 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 17 3267 . G 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 17 3268 . G 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 17 3269 . G 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 17 3270 . T 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 17 3271 . G 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 17 3272 . G 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 17 3273 . A 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 17 3274 . T 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 17 3275 . C 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 17 3276 . A 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 17 3277 . C 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 17 3278 . T 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 17 3279 . T 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 17 3280 . G 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 17 3281 . A 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 17 3282 . G 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 17 3283 . G 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 17 3284 . T 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 17 3285 . C 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 17 3286 . A 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 17 3287 . G 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 17 3288 . G 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 17 3289 . A 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 17 3290 . G 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 17 3291 . T 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 17 3292 . T 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 17 3293 . C 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 17 3294 . A 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 17 3295 . A 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 17 3296 . G 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 17 3297 . A 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 17 3298 . C 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 17 3299 . C 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 17 3300 . A 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 17 3301 . G 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 17 3302 . C 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 17 3303 . C 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 17 3304 . T 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 17 3305 . G 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 17 3306 . G 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 17 3307 . C 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 17 3308 . C 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 17 3309 . A 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 17 3310 . A 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 17 3311 . C 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 17 3312 . A 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 17 3313 . T 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 17 3314 . G 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 17 3315 . G 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 17 3316 . T 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 17 3317 . G 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 17 3318 . A 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 17 3319 . A 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 17 3320 . A 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 17 3321 . C 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 17 3322 . C 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 17 3323 . C 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 17 3324 . C 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 17 3325 . G 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 17 3326 . T 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 17 3327 . C 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 17 3328 . T 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 17 3329 . A 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 17 3330 . C 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 17 3331 . T 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 17 3332 . A 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 17 3333 . A 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 17 3334 . A 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 17 3335 . A 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 17 3336 . A 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 17 3337 . T 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 17 3338 . A 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 17 3339 . C 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 17 3340 . A 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 17 3341 . A 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 17 3342 . A 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 17 3343 . A 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 17 3344 . A 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 17 3345 . T 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 17 3346 . T 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 17 3347 . A 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 17 3348 . G 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 17 3349 . C 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 17 3350 . C 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 17 3351 . T 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 17 3352 . G 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 17 3353 . G 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 17 3354 . C 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 17 3355 . G 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 17 3356 . T 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 17 3357 . G 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 17 3358 . G 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 17 3359 . T 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 17 3360 . G 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 17 3361 . G 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 17 3362 . C 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 17 3363 . G 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 17 3364 . C 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 17 3365 . A 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 17 3366 . T 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 17 3367 . G 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 17 3368 . C 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 17 3369 . C 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 17 3370 . T 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 17 3371 . G 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 17 3372 . T 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 17 3373 . A 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 17 3374 . A 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 17 3375 . T 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 17 3376 . C 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 17 3377 . C 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 17 3378 . C 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 17 3379 . A 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 17 3380 . G 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 17 3381 . C 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 17 3382 . T 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 17 3383 . A 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 17 3384 . C 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 17 3385 . T 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 17 3386 . T 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 17 3387 . G 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 17 3388 . G 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 17 3389 . G 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 17 3390 . A 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 17 3391 . A 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 17 3392 . G 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 17 3393 . C 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 17 3394 . T 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 17 3395 . G 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 17 3396 . A 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 17 3397 . G 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 17 3398 . G 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 17 3399 . G 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 17 3400 . A 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 17 3401 . T 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 17 3402 . G 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 17 3403 . A 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 17 3404 . G 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 17 3405 . A 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 17 3406 . A 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 17 3407 . C 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 17 3408 . T 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 17 3409 . G 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 17 3410 . C 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 17 3411 . T 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 17 3412 . T 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 17 3413 . G 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 17 3414 . A 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 17 3415 . A 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 17 3416 . C 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 17 3417 . C 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 17 3418 . T 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 17 3419 . G 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 17 3420 . G 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 17 3421 . G 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 17 3422 . A 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 17 3423 . G 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 17 3424 . G 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 17 3425 . C 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 17 3426 . A 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 17 3427 . G 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 17 3428 . A 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 17 3429 . C 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 17 3430 . G 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 17 3431 . T 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 17 3432 . T 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 17 3433 . G 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 17 3434 . C 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 17 3435 . A 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 17 3436 . G 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 17 3437 . T G, 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 17 3438 . G 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 17 3439 . A 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 17 3440 . G 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 17 3441 . C 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 17 3442 . T 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 17 3443 . G 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 17 3444 . A 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 17 3445 . G 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 17 3446 . A 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 17 3447 . T 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 17 3448 . C 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 17 3449 . A 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 17 3450 . C 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 17 3451 . G 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 17 3452 . C 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 17 3453 . C 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 17 3454 . A 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 17 3455 . C 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 17 3456 . T 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 17 3457 . G 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 17 3458 . C 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 17 3459 . A C, 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 17 3460 . C 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 17 3461 . T 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 17 3462 . C 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 17 3463 . C 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 17 3464 . A 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 17 3465 . G 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 17 3466 . C 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 17 3467 . C 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 17 3468 . T 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 17 3469 . G 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 17 3470 . G 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 17 3471 . G 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 17 3472 . C 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 17 3473 . A 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 17 3474 . A 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 17 3475 . C 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 17 3476 . A 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 17 3477 . G 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 17 3478 . A 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 17 3479 . G 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 17 3480 . T 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 17 3481 . A 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 17 3482 . A 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 17 3483 . G 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 17 3484 . A C, 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 17 3485 . C 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 17 3486 . T 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 17 3487 . C 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 17 3488 . T 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 17 3489 . G 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 17 3490 . T C, 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 17 3491 . C 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 17 3492 . T 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 17 3493 . C 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 17 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 17 3494 . A 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 17 3495 . A 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 17 3496 . A 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 17 3497 . A 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 17 3498 . A 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 17 3499 . A 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 17 3500 . A 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 17 3501 . A 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 17 3502 . A 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 17 3503 . A 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 17 3504 . A 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 17 3505 . A 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 17 3506 . A 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 17 3507 . T 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 17 3508 . C 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 17 3509 . A 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 17 3510 . C A, 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 17 3511 . A 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 17 3512 . C 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 17 3513 . C A, 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 17 3514 . A 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 17 3515 . T 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 17 3516 . T 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 17 3517 . T 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 17 3518 . T 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 17 3519 . G 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 17 3520 . G 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 17 3521 . C 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 17 3522 . T 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 17 3523 . T 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 17 3524 . C 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 17 3525 . A 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 17 3526 . G 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 17 3527 . A 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 17 3528 . T 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 17 3529 . T 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 17 3530 . G 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 17 3531 . C A, 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 17 3532 . A 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 17 3533 . T 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 17 3534 . A 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 17 3535 . T 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 17 3536 . C 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 17 3537 . C 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 17 3538 . T 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 17 3539 . C 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 17 3540 . C 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 17 3541 . T 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 17 3542 . G 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 17 3543 . C 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 17 3544 . A 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 17 3545 . A 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 17 3546 . G 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 17 3547 . G 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 17 3548 . A 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 17 3549 . T 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 17 3550 . A 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 17 3551 . T 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 17 3552 . A 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 17 3553 . T A, 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 17 3554 . A 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 17 3555 . C 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 17 3556 . G 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 17 3557 . C 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 17 3558 . G 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 17 3559 . T 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 17 3560 . G 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 17 3561 . A 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 17 3562 . A 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 17 3563 . A 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 17 3564 . T 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 17 3565 . T 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 17 3566 . C 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 17 3567 . A 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 17 3568 . A 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 17 3569 . G 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 17 3570 . T 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 17 3571 . C 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 17 3572 . A 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 17 3573 . A 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 17 3574 . T 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 17 3575 . G 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 17 3576 . A 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 17 3577 . C 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 17 3578 . A 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 17 3579 . A 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 17 3580 . A 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 17 3581 . T 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 17 3582 . C 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 17 3583 . A 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 17 3584 . G 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 17 3585 . A 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 17 3586 . A 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 17 3587 . G A, 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 17 3588 . A 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 17 3589 . A 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 17 3590 . A 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 17 3591 . A 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 17 3592 . A 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 17 3593 . A 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 17 3594 . C 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 17 3595 . A 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 17 3596 . T 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 17 3597 . A 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 17 3598 . T 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 17 3599 . A 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 17 3600 . T 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 17 3601 . A 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 17 3602 . T 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 17 3603 . A 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 17 3604 . C 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 17 3605 . G 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 17 3606 . C 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 17 3607 . A 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 17 3608 . A 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 17 3609 . A 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 17 3610 . C 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 17 3611 . C 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 17 3612 . A 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 17 3613 . G 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 17 3614 . T 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 17 3615 . A 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 17 3616 . T 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 17 3617 . C 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 17 3618 . C 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 17 3619 . T 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 17 3620 . A 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 17 3621 . C 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 17 3622 . T 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 17 3623 . G 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 17 3624 . T 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 17 3625 . G 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 17 3626 . T 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 17 3627 . G 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 17 3628 . T 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 17 3629 . G 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 17 3630 . T 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 17 3631 . C 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 17 3632 . G 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 17 3633 . T 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 17 3634 . T 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 17 3635 . T 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 17 3636 . G 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 17 3637 . T 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 17 3638 . T 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 17 3639 . G 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 17 3640 . T 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 17 3641 . G 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 17 3642 . T 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 17 3643 . T 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 17 3644 . T 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 17 3645 . T 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 17 3646 . C 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 17 3647 . G 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 17 3648 . A 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 17 3649 . C 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 17 3650 . A 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 17 3651 . G 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 17 3652 . C 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 17 3653 . T 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 17 3654 . G 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 17 3655 . T 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 17 3656 . C 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 17 3657 . C 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 17 3658 . G 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 17 3659 . T 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 17 3660 . G 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 17 3661 . T 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 17 3662 . T 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 17 3663 . A 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 17 3664 . T 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 17 3665 . A 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 17 3666 . A 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 17 3667 . T 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 17 3668 . A 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 17 3669 . A 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 17 3670 . T 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 17 3671 . T 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 17 3672 . C 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 17 3673 . C 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 17 3674 . T 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 17 3675 . C 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 17 3676 . T 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 17 3677 . A 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 17 3678 . G 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 17 3679 . T 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 17 3680 . T 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 17 3681 . C 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 17 3682 . A 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 17 3683 . A 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 17 3684 . A 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 17 3685 . T 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 17 3686 . T 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 17 3687 . T 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 17 3688 . A 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 17 3689 . T 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 17 3690 . T 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 17 3691 . C 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 17 3692 . A 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 17 3693 . T 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 17 3694 . T 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 17 3695 . T 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 17 3696 . T 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 17 3697 . T 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 17 3698 . A 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 17 3699 . A 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 17 3700 . C 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 17 3701 . T 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 17 3702 . T 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 17 3703 . C 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 17 3704 . A 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 17 3705 . T 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 17 3706 . A 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 17 3707 . G 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 17 3708 . T 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 17 3709 . A 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 17 3710 . C 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 17 3711 . C 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 17 3712 . A 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 17 3713 . C 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 17 3714 . A 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 17 3715 . T 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 17 3716 . T 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 17 3717 . C 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 17 3718 . T 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 17 3719 . A 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 17 3720 . C 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 17 3721 . A 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 17 3722 . C 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 17 3723 . A 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 17 3724 . C 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 17 3725 . T 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 17 3726 . G 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 17 3727 . C 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 17 3728 . C 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 17 3729 . C 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 17 3730 . A 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 17 3731 . T 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 17 3732 . G 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 17 3733 . T 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 17 3734 . C 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 17 3735 . C 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 17 3736 . C 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 17 3737 . C 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 17 3738 . T 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 17 3739 . C 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 17 3740 . A 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 17 3741 . A 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 17 3742 . G 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 17 3743 . C 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 17 3744 . T 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 17 3745 . T 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 17 3746 . C 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 17 3747 . C 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 17 3748 . C 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 17 3749 . C 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 17 3750 . T 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 17 3751 . G 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 17 3752 . G 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 17 3753 . C 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 17 3754 . T 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 17 3755 . C 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 17 3756 . C 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 17 3757 . T 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 17 3758 . G 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 17 3759 . C 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 17 3760 . A 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 17 3761 . A 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 17 3762 . C 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 17 3763 . C 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 17 3764 . A 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 17 3765 . C 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 17 3766 . A 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 17 3767 . A 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 17 3768 . A 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 17 3769 . T 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 17 3770 . C 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 17 3771 . T 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 17 3772 . A 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 17 3773 . C 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 17 3774 . T 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 17 3775 . C 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 17 3776 . T 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 17 3777 . C 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 17 3778 . T 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 17 3779 . G 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 17 3780 . C 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 17 3781 . C 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 17 3782 . T 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 17 3783 . C 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 17 3784 . T 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 17 3785 . G 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 17 3786 . T 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 17 3787 . G 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 17 3788 . G 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 17 3789 . G 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 17 3790 . T 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 17 3791 . T 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 17 3792 . G A, 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 17 3793 . A 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 17 3794 . C 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 17 3795 . C 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 17 3796 . T 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 17 3797 . A 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 17 3798 . T 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 17 3799 . T 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 17 3800 . C 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 17 3801 . T 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 17 3802 . G 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 17 3803 . G 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 17 3804 . A 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 17 3805 . C 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 17 3806 . A 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 17 3807 . C 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 17 3808 . G 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 17 3809 . T 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 17 3810 . C 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 17 3811 . A C, 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 17 3812 . T 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 17 3813 . A 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 17 3814 . G 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 17 3815 . A 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 17 3816 . A 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 17 3817 . A 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 17 3818 . T 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 17 3819 . A 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 17 3820 . G 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 17 3821 . A 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 17 3822 . G 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 17 3823 . T 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 17 3824 . C 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 17 3825 . C 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 17 3826 . T 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 17 3827 . G 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 17 3828 . C 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 17 3829 . A 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 17 3830 . A 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 17 3831 . C A, 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 17 3832 . A 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 17 3833 . C 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 17 3834 . G 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 17 3835 . T 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 17 3836 . G C, 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 17 3837 . G 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 17 3838 . C 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 17 3839 . C 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 17 3840 . G 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 17 3841 . T 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 17 3842 . C 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 17 3843 . T 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 17 3844 . G 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 17 3845 . T 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 17 3846 . G 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 17 3847 . T 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 17 3848 . C 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 17 3849 . T 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 17 3850 . G 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 17 3851 . G 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 17 3852 . C 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 17 3853 . T 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 17 3854 . T 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 17 3855 . C 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 17 3856 . T 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 17 3857 . C 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 17 3858 . T 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 17 3859 . C 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 17 3860 . G 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 17 3861 . C 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 17 3862 . T 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 17 3863 . T 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 17 3864 . A 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 17 3865 . G 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 17 3866 . C 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 17 3867 . A 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 17 3868 . T 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 17 3869 . C 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 17 3870 . T 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 17 3871 . T 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 17 3872 . G 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 17 3873 . T 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 17 3874 . T 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 17 3875 . T 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 17 3876 . C 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 17 3877 . C 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 17 3878 . A 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 17 3879 . A 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 17 3880 . G 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 17 3881 . G 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 17 3882 . T 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 17 3883 . C 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 17 3884 . C 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 17 3885 . T 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 17 3886 . C 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 17 3887 . C 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 17 3888 . C 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 17 3889 . A 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 17 3890 . C 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 17 3891 . A 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 17 3892 . G 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 17 3893 . T 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 17 3894 . G 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 17 3895 . T 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 17 3896 . A 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 17 3897 . G 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 17 3898 . C 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 17 3899 . A 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 17 3900 . T 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 17 3901 . G 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 17 3902 . C 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 17 3903 . A 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 17 3904 . C 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 17 3905 . C 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 17 3906 . T 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 17 3907 . G 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 17 3908 . C 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 17 3909 . T 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 17 3910 . A 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 17 3911 . C 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 17 3912 . A C, 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 17 3913 . C 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 17 3914 . T 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 17 3915 . C 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 17 3916 . C 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 17 3917 . T 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 17 3918 . T 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 17 3919 . C 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 17 3920 . T 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 17 3921 . T 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 17 3922 . A 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 17 3923 . G 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 17 3924 . G 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 17 3925 . G 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 17 3926 . C 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 17 3927 . T 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 17 3928 . G 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 17 3929 . A 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 17 3930 . T 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 17 3931 . A 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 17 3932 . T 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 17 3933 . T 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 17 3934 . C 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 17 3935 . C 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 17 3936 . A G, 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 17 3937 . C 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 17 3938 . G 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 17 3939 . C 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 17 3940 . A 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 17 3941 . C 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 17 3942 . C 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 17 3943 . T 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 17 3944 . G 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 17 3945 . C 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 17 3946 . T 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 17 3947 . A 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 17 3948 . C 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 17 3949 . A C, 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 17 3950 . C 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 17 3951 . T 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 17 3952 . C 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 17 3953 . C 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 17 3954 . T 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 17 3955 . T 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 17 3956 . C 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 17 3957 . T 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 17 3958 . T 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 17 3959 . A 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 17 3960 . T 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 17 3961 . G 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 17 3962 . G 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 17 3963 . C 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 17 3964 . T 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 17 3965 . G 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 17 3966 . A 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 17 3967 . T 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 17 3968 . A 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 17 3969 . T 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 17 3970 . T 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 17 3971 . C 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 17 3972 . C 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 17 3973 . A 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 17 3974 . C 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 17 3975 . G 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 17 3976 . C 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 17 3977 . A 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 17 3978 . C 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 17 3979 . C 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 17 3980 . T 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 17 3981 . G 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 17 3982 . C 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 17 3983 . T 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 17 3984 . A 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 17 3985 . C 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 17 3986 . A 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 17 3987 . C 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 17 3988 . T 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 17 3989 . C 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 17 3990 . C 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 17 3991 . T 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 17 3992 . T 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 17 3993 . C 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 17 3994 . T 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 17 3995 . T 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 17 3996 . A 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 17 3997 . G C, 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 17 3998 . G 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 17 3999 . G A, 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 17 4000 . C 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 17 4001 . T 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 17 4002 . G 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 17 4003 . A 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 17 4004 . T 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 17 4005 . A 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 17 4006 . T 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 17 4007 . T G, 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 17 4008 . C 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 17 4009 . C 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 17 4010 . A 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 17 4011 . C 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 17 4012 . A 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 17 4013 . C 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 17 4014 . A 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 17 4015 . C 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 17 4016 . C 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 17 4017 . C 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 17 4018 . G 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 17 4019 . C 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 17 4020 . T 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 17 4021 . A 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 17 4022 . C 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 17 4023 . A 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 17 4024 . C 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 17 4025 . T 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 17 4026 . C 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 17 4027 . C 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 17 4028 . T 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 17 4029 . T 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 17 4030 . C 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 17 4031 . T 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 17 4032 . T 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 17 4033 . A 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 17 4034 . G 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 17 4035 . G T, 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 17 4036 . G 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 17 4037 . C 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 17 4038 . T 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 17 4039 . G 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 17 4040 . A 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 17 4041 . T 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 17 4042 . A 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 17 4043 . T 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 17 4044 . T 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 17 4045 . C 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 17 4046 . C 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 17 4047 . A 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 17 4048 . C 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 17 4049 . G 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 17 4050 . C 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 17 4051 . A 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 17 4052 . C 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 17 4053 . C 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 17 4054 . C 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 17 4055 . G 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 17 4056 . C 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 17 4057 . T 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 17 4058 . A 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 17 4059 . C 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 17 4060 . A 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 17 4061 . C 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 17 4062 . T 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 17 4063 . C 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 17 4064 . C 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 17 4065 . T 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 17 4066 . T 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 17 4067 . C 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 17 4068 . T 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 17 4069 . T 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 17 4070 . A 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 17 4071 . G 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 17 4072 . G 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 17 4073 . G 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 17 4074 . C 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 17 4075 . T 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 17 4076 . G 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 17 4077 . A 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 17 4078 . T 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 17 4079 . A 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 17 4080 . T 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 17 4081 . T 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 17 4082 . C 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 17 4083 . C 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 17 4084 . A 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 17 4085 . C 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 17 4086 . G 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 17 4087 . C 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 17 4088 . A 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 17 4089 . C 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 17 4090 . C 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 17 4091 . T 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 17 4092 . G 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 17 4093 . C 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 17 4094 . T 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 17 4095 . A 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 17 4096 . C 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 17 4097 . A 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 17 4098 . C 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 17 4099 . T 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 17 4100 . C 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 17 4101 . C 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 bcftools-1.21/test/mpileup.cAls.2.out000066400000000000000000000060311467060157400174660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://test/mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 chr1 212740 . A G 483.052 . DP=73;VDB=0.520868;SGB=-1.38232;MQSB=1;MQ0F=0;AC=4;AN=4;DP4=0,0,39,4;MQ=60 GT:PL:DP:AD 1/1:255,72,0:24:0,24 1/1:255,57,0:19:0,19 chr1 320055 . A G 533.95 . DP=101;MQSB=1;MQ0F=0;AC=0;AN=4;DP4=52,9,0,0;MQ=60 GT:PL:DP:AD 0/0:0,87,255:29:29,0 0/0:0,96,255:32:32,0 chr1 486173 . A T 106.286 . DP=13;VDB=0.074936;SGB=0.620439;RPB=0.810265;MQB=1.01283;MQSB=1;BQB=0.810265;MQ0F=0;AC=1;AN=4;DP4=3,1,3,0;MQ=60 GT:PL:DP:AD 0/0:0,9,151:3:3,0 0/1:140,0,48:4:1,3 chr1 511277 . A G 483.052 . DP=50;VDB=0.0722735;SGB=-1.26186;MQSB=1;MQ0F=0;AC=4;AN=4;DP4=0,0,25,4;MQ=60 GT:PL:DP:AD 1/1:255,30,0:10:0,10 1/1:255,57,0:19:0,19 chr1 602567 . A G 7.04355 . DP=9;SGB=-0.516033;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0;AC=0;AN=4;DP4=3,1,1,0;MQ=60 GT:PL:DP:AD 0/0:0,3,60:1:1,0 0/0:29,0,140:4:3,1 chr1 639707 . T A 483.052 . DP=50;VDB=0.563111;SGB=-1.37269;MQSB=1;MQ0F=0;AC=4;AN=4;DP4=0,0,23,8;MQ=60 GT:PL:DP:AD 1/1:255,42,0:14:0,14 1/1:255,51,0:17:0,17 bcftools-1.21/test/mpileup.cAls.3.out000066400000000000000000000022211467060157400174640ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 69066 . C G 59.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,33 20 69093 . G A . . . GT . 20 69094 . G A . . . GT . 20 69408 . C T . . . GT . bcftools-1.21/test/mpileup.cAls.4.out000066400000000000000000000023431467060157400174720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 69066 . C G 59.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,33 20 69076 . A G 54.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,28 20 69093 . G A . . . GT . 20 69094 . G A . . . GT . 20 69408 . C T . . . GT . bcftools-1.21/test/mpileup.cAls.5.out000066400000000000000000000023051467060157400174710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 68799 . T C . . . GT . 20 68800 . A G . . . GT . 20 68810 . G A . . . GT . 20 69066 . C G 59.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,33 20 69094 . G A . . . GT . 20 69408 . C T . . . GT . bcftools-1.21/test/mpileup.cAls.6.out000066400000000000000000000035231467060157400174750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##contig= ##contig= ##contig= ##contig= ##ALT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 1368828 . GT G 61.5766 . DP=1;MQ0F=0;AC=0;AN=2;DP4=1,0,0,0;MQ=60 GT:PL 0/0:0,3,35 1 1368833 . TAAAAAAAAAAAAAAAA TAAAAAAAAAAAAAA 24.1741 . DP=2;AC=0;AN=2;DP4=0,1,1,0;MQ=60 GT:PL 0/0:6,0,6 1 1368833 . T C 39.5768 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,13 1 1368833 . T G . . . GT . 1 1368834 . A T 59.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=1,0,0,0;MQ=60 GT:PL 0/0:0,3,33 16 60288 . C A . . . GT . 17 355 . G A . . . GT . 20 58799 . T C . . . GT . 20 58799 . T C . . . GT . 20 68800 . A G . . . GT . 20 68810 . G A . . . GT . 20 69066 . C G . . . GT . 20 69094 . G A . . . GT . 20 69408 . C T . . . GT . 21 9411409 . T C . . . GT . 21 9411485 . C A . . . GT . 21 9411497 . A G . . . GT . 21 9412485 . C G . . . GT . bcftools-1.21/test/mpileup.cAls.7.out000066400000000000000000000064731467060157400175050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///hs37d5.fa ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 790667 . C T . . . GT . 1 116844268 . GA G 58.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=1,0,0,0;MQ=60 GT:PL 0/0:0,3,32 1 116844279 . GAAAAAAAAAAAAAAAA GAAAAAAAAAAAAAA 24.1741 . INDEL;IDV=1;IMF=0.5;DP=2;VDB=0.5;SGB=-0.379885;MQSB=1;MQ0F=0;AC=0;AN=2;DP4=0,1,1,0;MQ=60 GT:PL 0/0:6,0,6 1 116844450 . T A . . . GT . 20 68799 . T C . . . GT . 20 68810 . G A . . . GT . 20 69066 . C G 59.5765 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,33 20 69094 . G A . . . GT . 20 69408 . C T . . . GT . 21 9411409 . T C . . . GT . 21 9411485 . C A . . . GT . 21 9411497 . A G . . . GT . 21 9412485 . C G 78.5768 . DP=2;MQ0F=0;AC=0;AN=2;DP4=1,0,0,0;MQ=52 GT:PL 0/0:0,3,52 16 60288 . C A . . . GT . 17 355 . G A . . . GT . bcftools-1.21/test/mpileup.cAls.out000066400000000000000000000075761467060157400173450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 1 . A G,T . . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 17 2 . A T,G . . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 17 3 . A C . . DP=11;MQ0F=0;AC=0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 17 4 . A G,T,C 21.815 . DP=11;MQ0F=0;AC=0,0,0;AN=2;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV 0/0:1,2,3,7,8,10,11,12,14,15:5:0 ./.:.:3:0 ./.:.:3:0 17 5 . A G,T . . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 17 6 . A T,G . . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 17 7 . A T,G,C 21.5769 . DP=11;MQ0F=0;AC=0,0,0;AN=2;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV 0/0:1,2,3,4,5,6,2,3,5,3:5:0 ./.:.:3:0 ./.:.:3:0 17 828 . T C 409.29 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 17 2220 . G C 188.992 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=0;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/0:139,157,255:12:6 0/0:69,75,119:4:2 0/0:131,131,131:4:4 17 2564 . A AG 165.992 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=0;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/0:88,98,171:6:3 0/0:57,63,117:4:2 0/0:124,124,124:4:4 bcftools-1.21/test/mpileup.cals.1.tab000066400000000000000000000000221467060157400174560ustar00rootroot000000000000006 263708 CTT,C,CT bcftools-1.21/test/mpileup.cals.1.vcf000066400000000000000000000050541467060157400175000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=hs37d5.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12878 6 263708 . C <*> 0 . DP=211;I16=117,27,0,0,4635,154411,0,0,8284,486348,0,0,2730,59520,0,0;QS=1,0;MQSB=0.901445;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,255,255:144:0:117,0:27,0:144,0 6 263708 . CTTTTTTTTTTTTTT CTTTTTTTTTTTTT,CTTTTTTTTTTTTTTT,CTTTTTTTTTTTT 0 . INDEL;IDV=27;IMF=0.127358;DP=212;I16=100,83,20,9,3133,71279,800,23372,10402,608546,1663,97179,3447,74011,628,14310;QS=0.84686,0.0839802,0.0494001,0.0197601;VDB=0.0105186;SGB=-0.693079;MQSB=0.971475;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,255,39,255,51,39,255,74,57,39:212:8:100,12,7,1:83,5,3,1:183,17,10,2 bcftools-1.21/test/mpileup.cals.2.tab000066400000000000000000000004071467060157400174660ustar00rootroot000000000000001 1368828 GT,G 1 1368833 TAA,T 1 1368833 T,C 1 1368833 T,G 1 1368834 A,T 1 1370000 C,CT 16 60288 C,A 17 355 G,A 20 58799 T,C 20 58799 T,C 20 68800 A,G 20 68810 G,A 20 69066 C,G 20 69094 G,A 20 69408 C,T 21 9411409 T,C 21 9411485 C,A 21 9411497 A,G 21 9412485 C,G bcftools-1.21/test/mpileup.cals.2.vcf000066400000000000000000000022761467060157400175040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##contig= ##contig= ##contig= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 1368833 . T <*> 0 . DP=1;I16=0,1,0,0,13,169,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,13 1 1368833 . TAAAAAAAAAAAAAAAA TAAAAAAAAAAAAAA 0 . DP=2;I16=0,1,1,0,10,100,30,900,60,3600,60,3600,3,9,25,625;QS=0.5,0.5 PL 6,0,6 1 1370000 . C T,G,A 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL 0,0,0,0,0,0,.,.,.,. bcftools-1.21/test/mpileup.cals.8.out000066400000000000000000000050731467060157400175410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=hs37d5.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12878 6 263708 . CTT C,CT 27.0816 . INDEL;IDV=27;IMF=0.127358;DP=212;VDB=0.0105186;SGB=-0.693079;MQSB=0.971475;MQ0F=0;AC=0,0;AN=2;DP4=100,83,20,9;MQ=56 GT:PL:DP:SP:ADF:ADR:AD 0/0:0,255,39,255,74,39:212:8:100,1,12:83,1,5:183,2,17 bcftools-1.21/test/mpileup.cals.9.out000066400000000000000000000026101467060157400175340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://grch37.chr20.fa.gz ##contig= ##contig= ##contig= ##contig= ##contig= ##ALT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 1368833 . TAAAAAAAAAAAAAAAA TAAAAAAAAAAAAAA 24.1741 . DP=2;AC=0;AN=2;DP4=0,1,1,0;MQ=60 GT:PL 0/0:6,0,6 1 1368833 . T C 39.5768 . DP=1;MQ0F=0;AC=0;AN=2;DP4=0,1,0,0;MQ=60 GT:PL 0/0:0,3,13 1 1370000 . C CT . . DP=11;MQ0F=0;AC=0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL ./.:0,0,0 bcftools-1.21/test/mpileup.hwe.1.out000066400000000000000000000042451467060157400173730ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA19213 NA19129 15 201 . A G 202.049 . DP=80;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0;AC=4;AN=4;DP4=19,17,21,15;MQ=59 GT:PL:AD 1/1:144,12,0:0,4 1/1:85,9,0:0,3 bcftools-1.21/test/mpileup.hwe.1b.out000066400000000000000000000042451467060157400175350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA19213 NA19129 15 201 . A G 117.048 . DP=80;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0;AC=4;AN=4;DP4=19,17,21,15;MQ=59 GT:PL:AD 1/1:144,12,0:0,4 1/1:85,9,0:0,3 bcftools-1.21/test/mpileup.hwe.2.out000066400000000000000000000065271467060157400174010ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07000 NA07056 NA12046 NA12144 NA12156 NA12234 NA12249 NA12282 NA12283 NA12286 NA12340 NA12341 NA12342 NA12399 NA12414 NA12546 NA12717 NA12718 NA12748 NA12749 NA12750 NA12776 NA12828 NA12843 NA18502 NA18867 NA18908 NA18933 NA18934 NA19108 NA19117 NA19119 NA19129 NA19131 NA19138 NA19147 NA19149 NA19159 NA19185 NA19189 NA19197 NA19198 NA19206 NA19213 NA19214 NA19223 NA19235 NA19236 NA19238 NA19239 NA19248 NA19256 15 201 . A G 1051.64 . DP=80;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0;AC=69;AN=104;DP4=19,17,21,15;MQ=59 GT:PL:AD 0/1:0,3,36:1,0 0/0:0,6,93:2,0 0/1:0,3,33:1,0 0/1:0,3,32:1,0 0/1:0,3,36:1,0 0/1:0,3,32:1,0 0/1:0,3,40:1,0 0/0:0,6,79:2,0 0/1:0,3,42:1,0 0/0:0,6,64:2,0 0/0:0,6,67:2,0 0/0:0,6,66:2,0 0/0:0,9,96:3,0 0/1:0,3,32:1,0 0/1:0,3,36:1,0 0/1:0,3,31:1,0 0/1:0,3,44:1,0 0/1:0,3,44:1,0 0/0:0,6,61:2,0 0/1:0,3,60:1,0 0/0:0,6,60:2,0 0/0:0,6,57:2,0 0/1:0,3,31:1,0 0/0:0,6,68:2,0 0/1:0,3,60:1,0 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:37,3,0:0,1 1/1:60,3,0:0,1 1/1:38,3,0:0,1 1/1:36,3,0:0,1 1/1:37,3,0:0,1 1/1:85,9,0:0,3 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:63,6,0:0,2 1/1:29,3,0:0,1 1/1:32,3,0:0,1 1/1:43,3,0:0,1 1/1:27,3,0:0,1 1/1:43,3,0:0,1 1/1:34,3,0:0,1 1/1:46,3,0:0,1 1/1:144,12,0:0,4 1/1:59,3,0:0,1 1/1:16,3,0:0,1 1/1:37,3,0:0,1 1/1:57,6,0:0,2 1/1:91,6,0:0,2 1/1:21,3,0:0,1 1/1:52,6,0:0,2 1/1:26,3,0:0,1 bcftools-1.21/test/mpileup.hwe.3.out000066400000000000000000000103401467060157400173660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07000 NA07056 NA12046 NA12144 NA12156 NA12234 NA12249 NA12282 NA12283 NA12286 NA12340 NA12341 NA12342 NA12399 NA12414 NA12546 NA12717 NA12718 NA12748 NA12749 NA12750 NA12776 NA12828 NA12843 NA18502 NA18867 NA18908 NA18933 NA18934 NA19108 NA19117 NA19119 NA19129 NA19131 NA19138 NA19147 NA19149 NA19159 NA19185 NA19189 NA19197 NA19198 NA19206 NA19213 NA19214 NA19223 NA19235 NA19236 NA19238 NA19239 NA19248 NA19256 15 198 . C A 12.8224 . DP=79;SGB=-0.627953;RPB=1;MQB=1;MQSB=0.974642;BQB=1;MQ0F=0;AC=2;AN=104;DP4=40,31,0,1;MQ=59 GT:PL:AD 0/0:0,3,44:1,0 0/0:0,6,95:2,0 0/0:0,3,39:1,0 0/0:0,3,43:1,0 0/0:0,3,34:1,0 0/0:0,3,37:1,0 0/0:0,3,41:1,0 0/0:0,6,87:2,0 0/0:0,3,46:1,0 0/0:0,6,76:2,0 0/0:0,6,80:2,0 0/0:0,6,78:2,0 0/0:0,9,112:3,0 0/0:0,3,41:1,0 1/1:35,3,0:0,1 0/0:0,3,33:1,0 0/0:0,3,44:1,0 0/0:0,3,45:1,0 0/0:0,6,69:2,0 0/0:0,3,60:1,0 0/0:0,6,70:2,0 0/0:0,6,57:2,0 0/0:0,3,37:1,0 0/0:0,6,79:2,0 0/0:0,3,60:1,0 0/0:0,3,42:1,0 0/0:0,3,39:1,0 0/0:0,3,44:1,0 0/0:0,3,60:1,0 0/0:0,3,39:1,0 0/0:0,3,41:1,0 0/0:0,3,44:1,0 0/0:0,9,98:3,0 0/0:0,3,40:1,0 0/0:0,3,38:1,0 0/0:0,6,72:2,0 0/0:0,3,29:1,0 0/0:0,3,34:1,0 0/0:0,3,43:1,0 0/0:0,3,34:1,0 0/0:0,3,44:1,0 0/0:0,3,36:1,0 0/0:0,3,47:1,0 0/0:0,12,163:4,0 0/0:0,3,60:1,0 0/0:0,3,41:1,0 0/0:0,3,37:1,0 0/0:0,6,73:2,0 0/0:0,6,96:2,0 0/0:0,3,40:1,0 0/0:0,6,67:2,0 0/0:0,3,33:1,0 15 201 . A G 121.59 . DP=80;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0;AC=50;AN=104;DP4=19,17,21,15;MQ=59 GT:PL:AD 0/0:0,3,36:1,0 0/0:0,6,93:2,0 0/0:0,3,33:1,0 0/0:0,3,32:1,0 0/0:0,3,36:1,0 0/0:0,3,32:1,0 0/0:0,3,40:1,0 0/0:0,6,79:2,0 0/0:0,3,42:1,0 0/0:0,6,64:2,0 0/0:0,6,67:2,0 0/0:0,6,66:2,0 0/0:0,9,96:3,0 0/0:0,3,32:1,0 0/0:0,3,36:1,0 0/0:0,3,31:1,0 0/0:0,3,44:1,0 0/0:0,3,44:1,0 0/0:0,6,61:2,0 0/0:0,3,60:1,0 0/0:0,6,60:2,0 0/0:0,6,57:2,0 0/0:0,3,31:1,0 0/0:0,6,68:2,0 0/0:0,3,60:1,0 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:37,3,0:0,1 1/1:60,3,0:0,1 1/1:38,3,0:0,1 1/1:36,3,0:0,1 1/1:37,3,0:0,1 1/1:85,9,0:0,3 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:63,6,0:0,2 1/1:29,3,0:0,1 1/1:32,3,0:0,1 1/1:43,3,0:0,1 1/1:27,3,0:0,1 1/1:43,3,0:0,1 1/1:34,3,0:0,1 1/1:46,3,0:0,1 1/1:144,12,0:0,4 1/1:59,3,0:0,1 0/0:16,3,0:0,1 1/1:37,3,0:0,1 1/1:57,6,0:0,2 1/1:91,6,0:0,2 0/0:21,3,0:0,1 1/1:52,6,0:0,2 1/1:26,3,0:0,1 bcftools-1.21/test/mpileup.hwe.4.out000066400000000000000000000065271467060157400174030ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07000 NA07056 NA12046 NA12144 NA12156 NA12234 NA12249 NA12282 NA12283 NA12286 NA12340 NA12341 NA12342 NA12399 NA12414 NA12546 NA12717 NA12718 NA12748 NA12749 NA12750 NA12776 NA12828 NA12843 NA18502 NA18867 NA18908 NA18933 NA18934 NA19108 NA19117 NA19119 NA19129 NA19131 NA19138 NA19147 NA19149 NA19159 NA19185 NA19189 NA19197 NA19198 NA19206 NA19213 NA19214 NA19223 NA19235 NA19236 NA19238 NA19239 NA19248 NA19256 15 201 . A G 1211.32 . DP=80;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0;AC=55;AN=104;DP4=19,17,21,15;MQ=59 GT:PL:AD 0/0:0,3,36:1,0 0/0:0,6,93:2,0 0/0:0,3,33:1,0 0/0:0,3,32:1,0 0/0:0,3,36:1,0 0/0:0,3,32:1,0 0/0:0,3,40:1,0 0/0:0,6,79:2,0 0/0:0,3,42:1,0 0/0:0,6,64:2,0 0/0:0,6,67:2,0 0/0:0,6,66:2,0 0/0:0,9,96:3,0 0/0:0,3,32:1,0 0/0:0,3,36:1,0 0/0:0,3,31:1,0 0/0:0,3,44:1,0 0/0:0,3,44:1,0 0/0:0,6,61:2,0 0/0:0,3,60:1,0 0/0:0,6,60:2,0 0/0:0,6,57:2,0 0/0:0,3,31:1,0 0/0:0,6,68:2,0 0/1:0,3,60:1,0 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:37,3,0:0,1 1/1:60,3,0:0,1 1/1:38,3,0:0,1 1/1:36,3,0:0,1 1/1:37,3,0:0,1 1/1:85,9,0:0,3 1/1:39,3,0:0,1 1/1:31,3,0:0,1 1/1:63,6,0:0,2 1/1:29,3,0:0,1 1/1:32,3,0:0,1 1/1:43,3,0:0,1 1/1:27,3,0:0,1 1/1:43,3,0:0,1 1/1:34,3,0:0,1 1/1:46,3,0:0,1 1/1:144,12,0:0,4 1/1:59,3,0:0,1 1/1:16,3,0:0,1 1/1:37,3,0:0,1 1/1:57,6,0:0,2 1/1:91,6,0:0,2 1/1:21,3,0:0,1 1/1:52,6,0:0,2 1/1:26,3,0:0,1 bcftools-1.21/test/mpileup.hwe.samples000066400000000000000000000047001467060157400200650ustar00rootroot00000000000000NA06984 CEU NA06985 CEU NA06986 CEU NA06989 CEU NA06994 CEU NA07000 CEU NA07037 CEU NA07048 CEU NA07051 CEU NA07056 CEU NA07347 CEU NA07357 CEU NA10847 CEU NA10851 CEU NA11829 CEU NA11830 CEU NA11831 CEU NA11832 CEU NA11840 CEU NA11843 CEU NA11881 CEU NA11892 CEU NA11893 CEU NA11894 CEU NA11918 CEU NA11919 CEU NA11920 CEU NA11930 CEU NA11931 CEU NA11932 CEU NA11933 CEU NA11992 CEU NA11994 CEU NA11995 CEU NA12003 CEU NA12004 CEU NA12005 CEU NA12006 CEU NA12043 CEU NA12044 CEU NA12045 CEU NA12046 CEU NA12058 CEU NA12144 CEU NA12154 CEU NA12155 CEU NA12156 CEU NA12234 CEU NA12249 CEU NA12272 CEU NA12273 CEU NA12275 CEU NA12282 CEU NA12283 CEU NA12286 CEU NA12287 CEU NA12340 CEU NA12341 CEU NA12342 CEU NA12347 CEU NA12348 CEU NA12383 CEU NA12399 CEU NA12400 CEU NA12413 CEU NA12414 CEU NA12489 CEU NA12546 CEU NA12716 CEU NA12717 CEU NA12718 CEU NA12748 CEU NA12749 CEU NA12750 CEU NA12751 CEU NA12760 CEU NA12761 CEU NA12762 CEU NA12763 CEU NA12775 CEU NA12776 CEU NA12777 CEU NA12778 CEU NA12812 CEU NA12813 CEU NA12814 CEU NA12815 CEU NA12827 CEU NA12828 CEU NA12829 CEU NA12830 CEU NA12842 CEU NA12843 CEU NA12872 CEU NA12873 CEU NA12874 CEU NA12878 CEU NA12889 CEU NA12890 CEU NA18486 YRI NA18488 YRI NA18489 YRI NA18498 YRI NA18499 YRI NA18501 YRI NA18502 YRI NA18504 YRI NA18505 YRI NA18507 YRI NA18508 YRI NA18510 YRI NA18511 YRI NA18516 YRI NA18517 YRI NA18519 YRI NA18520 YRI NA18522 YRI NA18523 YRI NA18853 YRI NA18856 YRI NA18858 YRI NA18861 YRI NA18864 YRI NA18865 YRI NA18867 YRI NA18868 YRI NA18870 YRI NA18871 YRI NA18873 YRI NA18874 YRI NA18876 YRI NA18877 YRI NA18878 YRI NA18879 YRI NA18881 YRI NA18907 YRI NA18908 YRI NA18909 YRI NA18910 YRI NA18912 YRI NA18915 YRI NA18916 YRI NA18917 YRI NA18923 YRI NA18924 YRI NA18933 YRI NA18934 YRI NA19092 YRI NA19093 YRI NA19095 YRI NA19096 YRI NA19098 YRI NA19099 YRI NA19102 YRI NA19107 YRI NA19108 YRI NA19113 YRI NA19114 YRI NA19116 YRI NA19117 YRI NA19118 YRI NA19119 YRI NA19121 YRI NA19129 YRI NA19130 YRI NA19131 YRI NA19137 YRI NA19138 YRI NA19141 YRI NA19143 YRI NA19144 YRI NA19146 YRI NA19147 YRI NA19149 YRI NA19152 YRI NA19153 YRI NA19159 YRI NA19160 YRI NA19171 YRI NA19172 YRI NA19175 YRI NA19184 YRI NA19185 YRI NA19189 YRI NA19190 YRI NA19197 YRI NA19198 YRI NA19200 YRI NA19201 YRI NA19204 YRI NA19206 YRI NA19207 YRI NA19209 YRI NA19210 YRI NA19213 YRI NA19214 YRI NA19222 YRI NA19223 YRI NA19225 YRI NA19235 YRI NA19236 YRI NA19238 YRI NA19239 YRI NA19240 YRI NA19247 YRI NA19248 YRI NA19256 YRI NA19257 YRI bcftools-1.21/test/mpileup.hwe.vcf000066400000000000000000003756331467060157400172170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://hwe.fa ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA07000 NA07056 NA12046 NA12144 NA12156 NA12234 NA12249 NA12282 NA12283 NA12286 NA12340 NA12341 NA12342 NA12399 NA12414 NA12546 NA12717 NA12718 NA12748 NA12749 NA12750 NA12776 NA12828 NA12843 NA18502 NA18867 NA18908 NA18933 NA18934 NA19108 NA19117 NA19119 NA19129 NA19131 NA19138 NA19147 NA19149 NA19159 NA19185 NA19189 NA19197 NA19198 NA19206 NA19213 NA19214 NA19223 NA19235 NA19236 NA19238 NA19239 NA19248 NA19256 15 104 . T <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 105 . T <*> 0 . DP=3;I16=0,3,0,0,96,3074,0,0,180,10800,0,0,1,1,0,0;QS=3,0;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 15 106 . A <*> 0 . DP=6;I16=2,4,0,0,192,6356,0,0,360,21600,0,0,4,6,0,0;QS=6,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,20:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 15 107 . A <*> 0 . DP=6;I16=2,4,0,0,208,7242,0,0,360,21600,0,0,10,20,0,0;QS=6,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 15 108 . T <*> 0 . DP=6;I16=2,4,0,0,195,6389,0,0,360,21600,0,0,16,46,0,0;QS=6,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 15 109 . A <*> 0 . DP=8;I16=3,5,0,0,265,8887,0,0,480,28800,0,0,22,84,0,0;QS=7,0;MQSB=0.900802;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,6,53:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 15 110 . G <*> 0 . DP=8;I16=3,5,0,0,276,10100,0,0,480,28800,0,0,30,136,0,0;QS=7,0;MQSB=0.900802;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,6,52:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 15 111 . C <*> 0 . DP=9;I16=4,5,0,0,317,11527,0,0,540,32400,0,0,38,204,0,0;QS=8,0;MQSB=0.974597;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,19:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,6,66:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 15 112 . C <*> 0 . DP=10;I16=5,5,0,0,353,12841,0,0,600,36000,0,0,47,289,0,0;QS=9,0;MQSB=0.952347;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,6,66:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,22:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 15 113 . C <*> 0 . DP=11;I16=6,5,0,0,389,14237,0,0,660,39600,0,0,57,393,0,0;QS=10,0;MQSB=0.950952;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,6,72:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,25:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 15 114 . C <*> 0 . DP=11;I16=6,5,0,0,381,13845,0,0,660,39600,0,0,68,518,0,0;QS=10,0;MQSB=0.950952;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,18:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,6,72:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 15 115 . C <*> 0 . DP=12;I16=6,6,0,0,431,15769,0,0,720,43200,0,0,79,665,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,27:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,6,70:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 15 116 . T <*> 0 . DP=12;I16=6,6,0,0,445,16611,0,0,720,43200,0,0,91,835,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,38:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,6,65:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 15 117 . T <*> 0 . DP=12;I16=6,6,0,0,427,15425,0,0,720,43200,0,0,103,1029,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,3,37:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,6,61:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 15 118 . T <*> 0 . DP=12;I16=6,6,0,0,410,14150,0,0,720,43200,0,0,115,1247,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,37:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,57:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 15 119 . G <*> 0 . DP=13;I16=7,6,0,0,485,18577,0,0,780,46800,0,0,127,1489,0,0;QS=12,0;MQSB=0.961166;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,39:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,6,73:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,3,22:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 15 120 . C <*> 0 . DP=15;I16=8,7,0,0,575,22275,0,0,900,54000,0,0,140,1756,0,0;QS=14,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,3,40:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,6,71:2,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 15 121 . T <*> 0 . DP=17;I16=9,8,0,0,619,22745,0,0,1020,61200,0,0,155,2051,0,0;QS=16,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,3,39:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,6,64:2,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 15 122 . G <*> 0 . DP=20;I16=10,10,0,0,732,27282,0,0,1200,72000,0,0,172,2378,0,0;QS=19,0;MQSB=1;MQ0F=0 PL:AD 0,3,35:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,3,37:1,0 0,0,0:0,0 0,3,36:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,6,74:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,3,26:1,0 15 123 . C <*> 0 . DP=21;I16=10,11,0,0,808,31598,0,0,1260,75600,0,0,192,2742,0,0;QS=20,0;MQSB=1;MQ0F=0 PL:AD 0,3,37:1,0 0,0,0:0,0 0,3,22:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,3,43:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,6,73:2,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,46:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,42:1,0 0,0,0:0,0 0,3,35:1,0 15 124 . A <*> 0 . DP=22;I16=11,11,0,0,765,27073,0,0,1320,79200,0,0,213,3147,0,0;QS=21,0;MQSB=1;MQ0F=0 PL:AD 0,3,26:1,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,40:1,0 0,0,0:0,0 0,3,37:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,6,67:2,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,37:1,0 0,0,0:0,0 0,3,29:1,0 15 125 . T <*> 0 . DP=23;I16=11,11,0,0,818,31720,0,0,1320,79200,0,0,235,3595,0,0;QS=21,0;MQSB=1;MQ0F=0 PL:AD 0,3,32:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,0,0:0,0 0,3,39:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,61:2,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,39:1,0 0,0,0:0,0 0,3,29:1,0 15 126 . G <*> 0 . DP=24;I16=12,11,0,0,877,34859,0,0,1380,82800,0,0,257,4087,0,0;QS=22,0;MQSB=1;MQ0F=0 PL:AD 0,3,28:1,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,41:1,0 0,0,0:0,0 0,3,38:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,25:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,6,69:2,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,41:1,0 0,0,0:0,0 0,3,38:1,0 15 127 . A <*> 0 . DP=25;I16=13,11,0,0,894,35272,0,0,1440,86400,0,0,280,4624,0,0;QS=23,0;MQSB=1;MQ0F=0 PL:AD 0,3,35:1,0 0,3,16:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,0,0:0,0 0,3,42:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,62:2,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,35:1,0 0,3,46:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,39:1,0 0,0,0:0,0 0,3,31:1,0 15 128 . G <*> 0 . DP=25;I16=13,11,0,0,999,42987,0,0,1440,86400,0,0,304,5208,0,0;QS=23,0;MQSB=1;MQ0F=0 PL:AD 0,3,37:1,0 0,3,43:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,46:1,0 0,3,41:1,0 0,0,0:0,0 0,3,42:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,6,73:2,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,41:1,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,3,39:1,0 15 129 . C <*> 0 . DP=26;I16=13,12,0,0,994,41310,0,0,1500,90000,0,0,328,5840,0,0;QS=24,0;MQSB=1;MQ0F=0 PL:AD 0,3,40:1,0 0,3,47:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,0,0:0,0 0,3,43:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,6,61:2,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,37:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,39:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,42:1,0 0,0,0:0,0 0,3,37:1,0 15 130 . A <*> 0 . DP=26;I16=13,12,0,0,915,34857,0,0,1500,90000,0,0,352,6470,0,0;QS=24,0;MQSB=1;MQ0F=0 PL:AD 0,3,33:1,0 0,3,38:1,0 0,3,26:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,41:1,0 0,0,0:0,0 0,3,39:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,65:2,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,31:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,36:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,34:1,0 0,0,0:0,0 0,3,31:1,0 15 131 . A <*> 0 . DP=27;I16=13,12,0,0,945,37201,0,0,1500,90000,0,0,374,7046,0,0;QS=24,0;MQSB=1;MQ0F=0 PL:AD 0,3,37:1,0 0,3,40:1,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,68:2,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,33:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,38:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,36:1,0 0,0,0:0,0 0,3,33:1,0 15 132 . C <*> 0 . DP=28;I16=13,14,0,0,1117,47759,0,0,1620,97200,0,0,403,7613,0,0;QS=26,0;MQSB=1;MQ0F=0 PL:AD 0,3,45:1,0 0,3,41:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,36:1,0 0,3,36:1,0 0,3,48:1,0 0,3,46:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,6,70:2,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,37:1,0 0,3,37:1,0 0,0,0:0,0 0,3,38:1,0 0,3,39:1,0 0,3,40:1,0 0,3,46:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,3,38:1,0 15 133 . A <*> 0 . DP=28;I16=13,14,0,0,1035,41171,0,0,1620,97200,0,0,424,8140,0,0;QS=26,0;MQSB=1;MQ0F=0 PL:AD 0,3,37:1,0 0,3,39:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,3,40:1,0 0,3,40:1,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,64:2,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,31:1,0 0,3,36:1,0 0,0,0:0,0 0,3,31:1,0 0,3,35:1,0 0,3,37:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,37:1,0 0,0,0:0,0 0,3,31:1,0 15 134 . A <*> 0 . DP=28;I16=13,14,0,0,1037,41593,0,0,1620,97200,0,0,445,8709,0,0;QS=26,0;MQSB=1;MQ0F=0 PL:AD 0,3,40:1,0 0,3,40:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,3,37:1,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,68:2,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,33:1,0 0,3,31:1,0 0,0,0:0,0 0,3,33:1,0 0,3,37:1,0 0,3,38:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,36:1,0 0,0,0:0,0 0,3,33:1,0 15 135 . C <*> 0 . DP=29;I16=13,15,0,0,1149,49143,0,0,1657,98569,0,0,464,9218,0,0;QS=27,0;MQSB=0.956162;MQ0F=0 PL:AD 0,3,39:1,0 0,3,43:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,41:1,0 0,3,44:1,0 0,3,42:1,0 0,3,46:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,6,68:2,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,3,38:1,0 0,3,35:1,0 0,0,0:0,0 0,3,38:1,0 0,3,39:1,0 0,3,41:1,0 0,3,45:1,0 0,3,31:1,0 0,0,0:0,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,3,37:1,0 15 136 . C <*> 0 . DP=29;I16=13,15,0,0,1015,38757,0,0,1657,98569,0,0,484,9766,0,0;QS=27,0;MQSB=0.956162;MQ0F=0 PL:AD 0,3,35:1,0 0,3,43:1,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,42:1,0 0,3,37:1,0 0,3,34:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,71:2,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,33:1,0 0,3,28:1,0 0,0,0:0,0 0,3,31:1,0 0,3,40:1,0 0,3,40:1,0 0,3,31:1,0 0,3,24:1,0 0,0,0:0,0 0,3,40:1,0 0,3,32:1,0 0,0,0:0,0 0,3,33:1,0 15 137 . G <*> 0 . DP=33;I16=17,15,0,0,1132,43526,0,0,1897,112969,0,0,503,10303,0,0;QS=30,0;MQSB=0.949789;MQ0F=0 PL:AD 0,3,43:1,0 0,3,34:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,36:1,0 0,3,41:1,0 0,3,43:1,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,6,57:2,0 0,3,26:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,32:1,0 0,0,0:0,0 0,3,18:1,0 0,3,21:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,3,26:1,0 0,3,27:1,0 0,0,0:0,0 0,3,35:1,0 0,3,32:1,0 0,3,33:1,0 0,3,44:1,0 0,3,31:1,0 0,0,0:0,0 0,6,49:2,0 0,3,40:1,0 0,0,0:0,0 0,3,26:1,0 15 138 . T <*> 0 . DP=35;I16=18,16,0,0,1269,49695,0,0,2017,120169,0,0,525,10831,0,0;QS=32,0;MQSB=0.95293;MQ0F=0 PL:AD 0,3,35:1,0 0,3,37:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,37:1,0 0,3,43:1,0 0,3,41:1,0 0,3,36:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,61:2,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,0,0:0,0 0,3,43:1,0 0,3,32:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,30:1,0 0,3,35:1,0 0,0,0:0,0 0,3,38:1,0 0,3,34:1,0 0,3,36:1,0 0,3,44:1,0 0,3,31:1,0 0,0,0:0,0 0,6,64:2,0 0,3,37:1,0 0,3,31:1,0 0,3,30:1,0 15 139 . T <*> 0 . DP=36;I16=19,15,0,0,1221,45953,0,0,2017,120169,0,0,538,11254,0,0;QS=31,0;MQSB=0.947161;MQ0F=0 PL:AD 0,3,35:1,0 0,3,36:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,37:1,0 0,3,36:1,0 0,3,40:1,0 0,3,43:1,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,62:2,0 0,6,52:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,3,41:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,36:1,0 0,3,33:1,0 0,3,42:1,0 0,3,22:1,0 0,0,0:0,0 0,6,66:2,0 0,3,36:1,0 0,3,31:1,0 0,3,33:1,0 15 140 . A <*> 0 . DP=36;I16=19,16,0,0,1305,51345,0,0,2077,123769,0,0,572,11924,0,0;QS=32,0;MQSB=0.951725;MQ0F=0 PL:AD 0,3,40:1,0 0,3,36:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,40:1,0 0,3,43:1,0 0,3,39:1,0 0,3,46:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,60:2,0 0,6,48:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,34:1,0 0,0,0:0,0 0,3,32:1,0 0,3,36:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,30:1,0 0,3,41:1,0 0,0,0:0,0 0,3,41:1,0 0,3,34:1,0 0,3,31:1,0 0,3,45:1,0 0,3,35:1,0 0,0,0:0,0 0,6,64:2,0 0,3,39:1,0 0,3,29:1,0 0,3,30:1,0 15 141 . G <*> 0 . DP=37;I16=19,17,0,0,1458,62122,0,0,2137,127369,0,0,595,12491,0,0;QS=33,0;MQSB=0.955701;MQ0F=0 PL:AD 0,3,44:1,0 0,3,44:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,39:1,0 0,3,46:1,0 0,3,46:1,0 0,3,45:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,6,60:2,0 0,6,52:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,42:1,0 0,3,36:1,0 0,3,39:1,0 0,3,36:1,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,39:1,0 0,3,32:1,0 0,0,0:0,0 0,3,40:1,0 0,3,42:1,0 0,3,34:1,0 0,3,45:1,0 0,3,36:1,0 0,0,0:0,0 0,6,75:2,0 0,3,42:1,0 0,3,39:1,0 0,3,40:1,0 15 142 . A <*> 0 . DP=38;I16=20,17,0,0,1427,57597,0,0,2197,130969,0,0,619,13105,0,0;QS=34,0;MQSB=0.954622;MQ0F=0 PL:AD 0,3,40:1,0 0,3,38:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,40:1,0 0,3,44:1,0 0,3,43:1,0 0,3,47:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,6,63:2,0 0,6,54:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,41:1,0 0,3,35:1,0 0,3,35:1,0 0,3,35:1,0 0,3,32:1,0 0,3,45:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,32:1,0 0,3,37:1,0 0,0,0:0,0 0,3,41:1,0 0,3,33:1,0 0,3,35:1,0 0,3,45:1,0 0,3,35:1,0 0,0,0:0,0 0,6,68:2,0 0,3,39:1,0 0,3,33:1,0 0,3,32:1,0 15 143 . G <*> 0 . DP=39;I16=20,18,0,0,1568,67134,0,0,2257,134569,0,0,644,13768,0,0;QS=34,0;MQSB=0.958165;MQ0F=0 PL:AD 0,3,44:1,0 0,3,45:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,39:1,0 0,3,43:1,0 0,3,47:1,0 0,3,45:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,6,73:2,0 0,6,63:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,3,42:1,0 0,3,37:1,0 0,3,39:1,0 0,3,41:1,0 0,3,37:1,0 0,3,43:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,39:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,6,71:2,0 0,3,41:1,0 0,3,44:1,0 0,3,37:1,0 0,0,0:0,0 0,6,76:2,0 0,3,41:1,0 0,3,39:1,0 0,3,40:1,0 15 144 . A <*> 0 . DP=39;I16=20,18,0,0,1387,52979,0,0,2257,134569,0,0,670,14482,0,0;QS=34,0;MQSB=0.958165;MQ0F=0 PL:AD 0,3,41:1,0 0,3,36:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,3,39:1,0 0,3,39:1,0 0,3,40:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,58:2,0 0,6,56:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,41:1,0 0,3,30:1,0 0,3,36:1,0 0,3,40:1,0 0,3,30:1,0 0,3,39:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,32:1,0 0,3,35:1,0 0,0,0:0,0 0,3,36:1,0 0,6,66:2,0 0,3,34:1,0 0,3,37:1,0 0,3,27:1,0 0,0,0:0,0 0,6,69:2,0 0,3,36:1,0 0,3,33:1,0 0,3,32:1,0 15 145 . C <*> 0 . DP=39;I16=20,18,0,0,1564,66572,0,0,2257,134569,0,0,695,15197,0,0;QS=34,0;MQSB=0.958165;MQ0F=0 PL:AD 0,3,42:1,0 0,3,41:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,42:1,0 0,3,47:1,0 0,3,42:1,0 0,3,44:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,6,71:2,0 0,6,65:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,3,43:1,0 0,3,37:1,0 0,3,40:1,0 0,3,40:1,0 0,3,37:1,0 0,3,46:1,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,3,42:1,0 0,6,73:2,0 0,3,41:1,0 0,3,45:1,0 0,3,37:1,0 0,0,0:0,0 0,6,73:2,0 0,3,42:1,0 0,3,38:1,0 0,3,38:1,0 15 146 . C <*> 0 . DP=40;I16=20,19,0,0,1554,64798,0,0,2317,138169,0,0,718,15860,0,0;QS=35,0;MQSB=0.961295;MQ0F=0 PL:AD 0,3,43:1,0 0,3,41:1,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,43:1,0 0,3,48:1,0 0,3,42:1,0 0,3,40:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,3,26:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,6,70:2,0 0,6,57:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,3,44:1,0 0,3,37:1,0 0,3,41:1,0 0,3,41:1,0 0,3,33:1,0 0,3,45:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,33:1,0 0,3,40:1,0 0,0,0:0,0 0,3,43:1,0 0,6,74:2,0 0,3,40:1,0 0,3,42:1,0 0,3,37:1,0 0,0,0:0,0 0,6,75:2,0 0,3,41:1,0 0,3,39:1,0 0,3,34:1,0 15 147 . C <*> 0 . DP=43;I16=21,20,0,0,1636,68448,0,0,2437,145369,0,0,715,15843,0,0;QS=36,0;MQSB=0.963194;MQ0F=0 PL:AD 0,3,44:1,0 0,6,58:2,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,40:1,0 0,3,48:1,0 0,3,45:1,0 0,3,46:1,0 0,3,32:1,0 0,3,41:1,0 0,0,0:0,0 0,3,29:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,42:1,0 0,6,54:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,46:1,0 0,3,44:1,0 0,3,38:1,0 0,3,40:1,0 0,3,42:1,0 0,6,69:2,0 0,3,43:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,33:1,0 0,3,41:1,0 0,0,0:0,0 0,3,41:1,0 0,6,76:2,0 0,3,40:1,0 0,3,45:1,0 0,3,37:1,0 0,0,0:0,0 0,6,76:2,0 0,3,42:1,0 0,3,39:1,0 0,3,34:1,0 15 148 . A <*> 0 . DP=45;I16=22,21,0,0,1637,65457,0,0,2557,152569,0,0,761,16919,0,0;QS=37,0;MQSB=0.964916;MQ0F=0 PL:AD 0,3,38:1,0 0,6,75:2,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,42:1,0 0,3,44:1,0 0,3,44:1,0 0,3,39:1,0 0,3,30:1,0 0,3,34:1,0 0,3,26:1,0 0,3,31:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,65:2,0 0,6,57:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,3,31:1,0 0,3,38:1,0 0,3,41:1,0 0,6,63:2,0 0,3,43:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,3,40:1,0 0,6,69:2,0 0,3,60:1,0 0,3,43:1,0 0,3,31:1,0 0,0,0:0,0 0,6,72:2,0 0,3,35:1,0 0,3,33:1,0 0,3,32:1,0 15 149 . T <*> 0 . DP=45;I16=22,21,0,0,1586,61848,0,0,2557,152569,0,0,782,17362,0,0;QS=37,0;MQSB=0.964916;MQ0F=0 PL:AD 0,3,35:1,0 0,6,70:2,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,36:1,0 0,3,43:1,0 0,3,44:1,0 0,3,43:1,0 0,3,30:1,0 0,3,31:1,0 0,3,30:1,0 0,3,29:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,63:2,0 0,6,56:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,42:1,0 0,3,31:1,0 0,3,37:1,0 0,3,40:1,0 0,6,61:2,0 0,3,40:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,31:1,0 0,3,34:1,0 0,0,0:0,0 0,3,37:1,0 0,6,66:2,0 0,3,60:1,0 0,3,42:1,0 0,3,34:1,0 0,0,0:0,0 0,6,70:2,0 0,3,31:1,0 0,3,34:1,0 0,3,32:1,0 15 150 . A <*> 0 . DP=45;I16=22,21,0,0,1554,59480,0,0,2557,152569,0,0,802,17796,0,0;QS=37,0;MQSB=0.964916;MQ0F=0 PL:AD 0,3,33:1,0 0,6,62:2,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,41:1,0 0,3,41:1,0 0,3,39:1,0 0,3,43:1,0 0,3,30:1,0 0,3,33:1,0 0,3,28:1,0 0,3,30:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,53:2,0 0,6,55:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,3,30:1,0 0,3,33:1,0 0,3,39:1,0 0,6,61:2,0 0,3,36:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,30:1,0 0,3,36:1,0 0,0,0:0,0 0,3,41:1,0 0,6,68:2,0 0,3,60:1,0 0,3,39:1,0 0,3,31:1,0 0,0,0:0,0 0,6,69:2,0 0,3,35:1,0 0,3,31:1,0 0,3,31:1,0 15 151 . C <*> 0 . DP=46;I16=23,21,0,0,1807,77531,0,0,2617,156169,0,0,822,18270,0,0;QS=38,0;MQSB=0.96415;MQ0F=0 PL:AD 0,3,40:1,0 0,6,75:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,42:1,0 0,3,48:1,0 0,3,48:1,0 0,3,42:1,0 0,3,37:1,0 0,3,38:1,0 0,3,39:1,0 0,3,39:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,6,53:2,0 0,6,66:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,3,43:1,0 0,3,40:1,0 0,3,40:1,0 0,3,37:1,0 0,6,77:2,0 0,3,40:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,38:1,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,6,78:2,0 0,3,60:1,0 0,3,45:1,0 0,3,37:1,0 0,3,34:1,0 0,6,75:2,0 0,3,43:1,0 0,3,38:1,0 0,3,38:1,0 15 152 . T <*> 0 . DP=47;I16=24,21,0,0,1738,71262,0,0,2677,159769,0,0,842,18734,0,0;QS=39,0;MQSB=0.963419;MQ0F=0 PL:AD 0,3,40:1,0 0,6,74:2,0 0,3,19:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,39:1,0 0,3,45:1,0 0,3,45:1,0 0,3,34:1,0 0,3,36:1,0 0,3,36:1,0 0,3,36:1,0 0,3,25:1,0 0,3,40:1,0 0,0,0:0,0 0,3,21:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,6,65:2,0 0,6,63:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,42:1,0 0,3,34:1,0 0,3,38:1,0 0,3,43:1,0 0,6,70:2,0 0,3,44:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,3,36:1,0 0,3,39:1,0 0,0,0:0,0 0,3,38:1,0 0,6,76:2,0 0,3,60:1,0 0,3,44:1,0 0,3,30:1,0 0,3,34:1,0 0,6,74:2,0 0,3,39:1,0 0,3,38:1,0 0,3,36:1,0 15 153 . T <*> 0 . DP=49;I16=24,22,0,0,1753,70297,0,0,2737,163369,0,0,862,19188,0,0;QS=40,0;MQSB=0.965783;MQ0F=0 PL:AD 0,3,39:1,0 0,6,65:2,0 0,3,38:1,0 0,3,34:1,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,3,45:1,0 0,3,45:1,0 0,3,44:1,0 0,3,32:1,0 0,3,34:1,0 0,3,30:1,0 0,3,33:1,0 0,3,40:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,55:2,0 0,6,58:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,42:1,0 0,3,32:1,0 0,3,35:1,0 0,3,41:1,0 0,6,65:2,0 0,3,44:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,33:1,0 0,3,40:1,0 0,0,0:0,0 0,3,41:1,0 0,6,71:2,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,32:1,0 0,6,70:2,0 0,3,38:1,0 0,3,35:1,0 0,3,33:1,0 15 154 . G <*> 0 . DP=49;I16=24,23,0,0,1951,84431,0,0,2797,166969,0,0,907,20259,0,0;QS=41,0;MQSB=0.967917;MQ0F=0 PL:AD 0,3,44:1,0 0,6,76:2,0 0,3,41:1,0 0,3,43:1,0 0,0,0:0,0 0,3,39:1,0 0,3,39:1,0 0,3,46:1,0 0,3,46:1,0 0,3,40:1,0 0,3,40:1,0 0,3,36:1,0 0,3,37:1,0 0,3,35:1,0 0,3,42:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,6,65:2,0 0,6,66:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,42:1,0 0,3,44:1,0 0,3,39:1,0 0,3,40:1,0 0,3,40:1,0 0,6,77:2,0 0,3,44:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,3,37:1,0 0,0,0:0,0 0,3,40:1,0 0,6,81:2,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,40:1,0 0,6,78:2,0 0,3,40:1,0 0,3,38:1,0 0,3,39:1,0 15 155 . T <*> 0 . DP=51;I16=25,24,0,0,1730,64616,0,0,2917,174169,0,0,928,20794,0,0;QS=42,0;MQSB=0.969233;MQ0F=0 PL:AD 0,3,35:1,0 0,6,73:2,0 0,3,33:1,0 0,3,22:1,0 0,0,0:0,0 0,3,33:1,0 0,3,41:1,0 0,3,39:1,0 0,3,43:1,0 0,3,43:1,0 0,3,28:1,0 0,3,33:1,0 0,6,56:2,0 0,3,28:1,0 0,3,34:1,0 0,0,0:0,0 0,3,37:1,0 0,3,20:1,0 0,0,0:0,0 0,3,29:1,0 0,6,64:2,0 0,6,54:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,33:1,0 0,3,42:1,0 0,3,30:1,0 0,3,36:1,0 0,3,33:1,0 0,6,61:2,0 0,3,39:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,30:1,0 0,3,40:1,0 0,0,0:0,0 0,3,39:1,0 0,6,65:2,0 0,3,60:1,0 0,3,41:1,0 0,3,34:1,0 0,3,33:1,0 0,6,70:2,0 0,3,34:1,0 0,3,31:1,0 0,3,30:1,0 15 156 . A <*> 0 . DP=51;I16=25,24,0,0,1839,73129,0,0,2917,174169,0,0,950,21322,0,0;QS=42,0;MQSB=0.969233;MQ0F=0 PL:AD 0,3,40:1,0 0,6,61:2,0 0,3,29:1,0 0,3,34:1,0 0,0,0:0,0 0,3,37:1,0 0,3,37:1,0 0,3,47:1,0 0,3,47:1,0 0,3,46:1,0 0,3,30:1,0 0,3,37:1,0 0,6,65:2,0 0,3,35:1,0 0,3,38:1,0 0,0,0:0,0 0,3,37:1,0 0,3,36:1,0 0,0,0:0,0 0,3,30:1,0 0,6,55:2,0 0,6,52:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,35:1,0 0,0,0:0,0 0,3,45:1,0 0,3,41:1,0 0,3,36:1,0 0,3,32:1,0 0,3,31:1,0 0,6,66:2,0 0,3,44:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,30:1,0 0,3,38:1,0 0,0,0:0,0 0,3,43:1,0 0,6,72:2,0 0,3,60:1,0 0,3,45:1,0 0,3,36:1,0 0,3,33:1,0 0,6,69:2,0 0,3,38:1,0 0,3,32:1,0 0,3,31:1,0 15 157 . G <*> 0 . DP=52;I16=25,25,0,0,2057,88513,0,0,2977,177769,0,0,972,21894,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,42:1,0 0,6,75:2,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,3,41:1,0 0,3,43:1,0 0,3,46:1,0 0,3,46:1,0 0,3,44:1,0 0,3,35:1,0 0,3,38:1,0 0,6,69:2,0 0,3,39:1,0 0,3,42:1,0 0,0,0:0,0 0,3,41:1,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,6,69:2,0 0,6,61:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,3,38:1,0 0,3,42:1,0 0,3,39:1,0 0,6,77:2,0 0,3,44:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,40:1,0 0,3,44:1,0 0,0,0:0,0 0,3,39:1,0 0,9,97:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,41:1,0 0,6,78:2,0 0,3,40:1,0 0,3,39:1,0 0,3,40:1,0 15 158 . T <*> 0 . DP=52;I16=25,25,0,0,1879,75001,0,0,2977,177769,0,0,994,22460,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,39:1,0 0,6,66:2,0 0,3,38:1,0 0,3,33:1,0 0,0,0:0,0 0,3,38:1,0 0,3,41:1,0 0,3,45:1,0 0,3,43:1,0 0,3,45:1,0 0,3,28:1,0 0,3,36:1,0 0,6,63:2,0 0,3,35:1,0 0,3,37:1,0 0,0,0:0,0 0,3,39:1,0 0,3,37:1,0 0,0,0:0,0 0,3,30:1,0 0,6,65:2,0 0,6,53:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,34:1,0 0,0,0:0,0 0,3,43:1,0 0,3,37:1,0 0,3,32:1,0 0,3,35:1,0 0,3,38:1,0 0,6,63:2,0 0,3,44:1,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,30:1,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,9,85:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,33:1,0 0,6,71:2,0 0,3,39:1,0 0,3,31:1,0 0,3,31:1,0 15 159 . G <*> 0 . DP=52;I16=25,25,0,0,2082,90542,0,0,2977,177769,0,0,1016,23070,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,42:1,0 0,6,79:2,0 0,3,41:1,0 0,3,33:1,0 0,0,0:0,0 0,3,42:1,0 0,3,43:1,0 0,3,46:1,0 0,3,46:1,0 0,3,40:1,0 0,3,39:1,0 0,3,37:1,0 0,6,65:2,0 0,3,35:1,0 0,3,43:1,0 0,0,0:0,0 0,3,43:1,0 0,3,37:1,0 0,0,0:0,0 0,3,40:1,0 0,6,72:2,0 0,6,62:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,39:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,3,38:1,0 0,3,39:1,0 0,3,44:1,0 0,6,75:2,0 0,3,45:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,39:1,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,9,108:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,41:1,0 0,6,78:2,0 0,3,42:1,0 0,3,40:1,0 0,3,35:1,0 15 160 . A <*> 0 . DP=52;I16=25,25,0,0,1849,72075,0,0,2977,177769,0,0,1038,23724,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,37:1,0 0,6,68:2,0 0,3,36:1,0 0,3,32:1,0 0,0,0:0,0 0,3,33:1,0 0,3,41:1,0 0,3,43:1,0 0,3,38:1,0 0,3,40:1,0 0,3,31:1,0 0,3,34:1,0 0,6,57:2,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,3,40:1,0 0,3,40:1,0 0,0,0:0,0 0,3,32:1,0 0,6,63:2,0 0,6,55:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,33:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,3,30:1,0 0,3,37:1,0 0,3,35:1,0 0,6,64:2,0 0,3,42:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,3,38:1,0 0,9,95:3,0 0,3,60:1,0 0,3,42:1,0 0,3,31:1,0 0,3,35:1,0 0,6,69:2,0 0,3,37:1,0 0,3,29:1,0 0,3,31:1,0 15 161 . C <*> 0 . DP=52;I16=25,25,0,0,2094,91616,0,0,2977,177769,0,0,1059,24371,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,44:1,0 0,6,74:2,0 0,3,39:1,0 0,3,31:1,0 0,0,0:0,0 0,3,34:1,0 0,3,43:1,0 0,3,47:1,0 0,3,47:1,0 0,3,46:1,0 0,3,38:1,0 0,3,41:1,0 0,6,71:2,0 0,3,41:1,0 0,3,45:1,0 0,0,0:0,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,3,39:1,0 0,6,73:2,0 0,6,65:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,37:1,0 0,0,0:0,0 0,3,45:1,0 0,3,43:1,0 0,3,40:1,0 0,3,41:1,0 0,3,38:1,0 0,6,78:2,0 0,3,38:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,3,38:1,0 0,3,39:1,0 0,0,0:0,0 0,3,44:1,0 0,9,109:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,39:1,0 0,6,76:2,0 0,3,43:1,0 0,3,38:1,0 0,3,38:1,0 15 162 . T <*> 0 . DP=52;I16=25,25,0,0,1970,81886,0,0,2977,177769,0,0,1080,25060,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,39:1,0 0,6,71:2,0 0,3,38:1,0 0,3,37:1,0 0,0,0:0,0 0,3,28:1,0 0,3,44:1,0 0,3,45:1,0 0,3,45:1,0 0,3,45:1,0 0,3,36:1,0 0,3,35:1,0 0,6,64:2,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,0,0:0,0 0,3,36:1,0 0,6,70:2,0 0,6,63:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,30:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,3,32:1,0 0,3,39:1,0 0,3,40:1,0 0,6,68:2,0 0,3,39:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,36:1,0 0,3,37:1,0 0,0,0:0,0 0,3,41:1,0 0,9,101:3,0 0,3,60:1,0 0,3,43:1,0 0,3,27:1,0 0,3,38:1,0 0,6,77:2,0 0,3,37:1,0 0,3,36:1,0 0,3,36:1,0 15 163 . G <*> 0 . DP=52;I16=25,25,0,0,2086,91372,0,0,2977,177769,0,0,1097,25587,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,44:1,0 0,6,76:2,0 0,3,41:1,0 0,3,39:1,0 0,0,0:0,0 0,3,34:1,0 0,3,44:1,0 0,3,47:1,0 0,3,46:1,0 0,3,45:1,0 0,3,41:1,0 0,3,40:1,0 0,6,67:2,0 0,3,39:1,0 0,3,44:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,0,0:0,0 0,3,40:1,0 0,6,61:2,0 0,6,65:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,36:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,3,38:1,0 0,3,42:1,0 0,3,44:1,0 0,6,73:2,0 0,3,41:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,3,38:1,0 0,0,0:0,0 0,3,44:1,0 0,9,108:3,0 0,3,60:1,0 0,3,44:1,0 0,3,34:1,0 0,3,42:1,0 0,6,75:2,0 0,3,42:1,0 0,3,38:1,0 0,3,40:1,0 15 164 . A <*> 0 . DP=53;I16=25,25,0,0,1976,83678,0,0,2977,177769,0,0,1112,26046,0,0;QS=42,0;MQSB=0.971017;MQ0F=0 PL:AD 0,3,39:1,0 0,6,67:2,0 0,3,36:1,0 0,3,38:1,0 0,0,0:0,0 0,3,36:1,0 0,3,41:1,0 0,3,47:1,0 0,3,44:1,0 0,3,46:1,0 0,3,33:1,0 0,3,38:1,0 0,6,65:2,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,3,41:1,0 0,3,40:1,0 0,0,0:0,0 0,3,32:1,0 0,6,63:2,0 0,6,44:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,36:1,0 0,0,0:0,0 0,3,45:1,0 0,3,42:1,0 0,3,35:1,0 0,3,37:1,0 0,3,39:1,0 0,6,68:2,0 0,3,42:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,32:1,0 0,3,34:1,0 0,0,0:0,0 0,3,47:1,0 0,9,107:3,0 0,3,60:1,0 0,3,45:1,0 0,3,32:1,0 0,3,35:1,0 0,6,91:2,0 0,3,38:1,0 0,3,32:1,0 0,3,32:1,0 15 165 . G <*> 0 . DP=54;I16=25,26,0,0,2147,95859,0,0,3037,181369,0,0,1126,26484,0,0;QS=42,0;MQSB=0.972644;MQ0F=0 PL:AD 0,3,43:1,0 0,6,75:2,0 0,3,31:1,0 0,3,37:1,0 0,0,0:0,0 0,3,31:1,0 0,3,43:1,0 0,3,46:1,0 0,3,46:1,0 0,6,74:2,0 0,3,39:1,0 0,3,40:1,0 0,6,65:2,0 0,3,36:1,0 0,3,42:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,0,0:0,0 0,3,40:1,0 0,6,69:2,0 0,6,68:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,3,37:1,0 0,3,42:1,0 0,3,43:1,0 0,6,76:2,0 0,3,41:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,40:1,0 0,3,44:1,0 0,0,0:0,0 0,3,41:1,0 0,9,109:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,41:1,0 0,6,95:2,0 0,3,40:1,0 0,3,36:1,0 0,3,40:1,0 15 166 . A <*> 0 . DP=54;I16=25,26,0,0,1926,77530,0,0,3037,181369,0,0,1141,26951,0,0;QS=42,0;MQSB=0.972644;MQ0F=0 PL:AD 0,3,37:1,0 0,6,64:2,0 0,3,38:1,0 0,3,41:1,0 0,0,0:0,0 0,3,40:1,0 0,3,39:1,0 0,3,43:1,0 0,3,38:1,0 0,6,73:2,0 0,3,31:1,0 0,3,32:1,0 0,6,58:2,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,3,38:1,0 0,3,41:1,0 0,0,0:0,0 0,3,32:1,0 0,6,63:2,0 0,6,57:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,42:1,0 0,3,35:1,0 0,3,30:1,0 0,3,37:1,0 0,3,41:1,0 0,6,63:2,0 0,3,37:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,32:1,0 0,3,36:1,0 0,0,0:0,0 0,3,40:1,0 0,9,96:3,0 0,3,60:1,0 0,3,42:1,0 0,3,30:1,0 0,3,36:1,0 0,6,91:2,0 0,3,34:1,0 0,3,32:1,0 0,3,32:1,0 15 167 . C <*> 0 . DP=54;I16=25,26,0,0,2166,97010,0,0,3037,181369,0,0,1155,27397,0,0;QS=42,0;MQSB=0.972644;MQ0F=0 PL:AD 0,3,43:1,0 0,6,78:2,0 0,3,41:1,0 0,3,43:1,0 0,0,0:0,0 0,3,36:1,0 0,3,29:1,0 0,3,48:1,0 0,3,47:1,0 0,6,81:2,0 0,3,38:1,0 0,3,38:1,0 0,6,70:2,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,3,43:1,0 0,0,0:0,0 0,3,38:1,0 0,6,74:2,0 0,6,63:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,38:1,0 0,0,0:0,0 0,3,46:1,0 0,3,44:1,0 0,3,39:1,0 0,3,41:1,0 0,3,30:1,0 0,6,75:2,0 0,3,42:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,38:1,0 0,3,42:1,0 0,0,0:0,0 0,3,47:1,0 0,9,115:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,39:1,0 0,6,95:2,0 0,3,36:1,0 0,3,37:1,0 0,3,37:1,0 15 168 . A <*> 0 . DP=54;I16=25,26,0,0,1949,79835,0,0,3037,181369,0,0,1168,27820,0,0;QS=42,0;MQSB=0.972644;MQ0F=0 PL:AD 0,3,37:1,0 0,6,71:2,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,3,31:1,0 0,3,40:1,0 0,3,43:1,0 0,3,43:1,0 0,6,68:2,0 0,3,34:1,0 0,3,32:1,0 0,6,57:2,0 0,3,32:1,0 0,3,37:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,32:1,0 0,6,66:2,0 0,6,56:2,0 0,0,0:0,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,42:1,0 0,3,40:1,0 0,3,30:1,0 0,3,38:1,0 0,3,43:1,0 0,6,61:2,0 0,3,34:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,3,39:1,0 0,9,96:3,0 0,3,60:1,0 0,3,38:1,0 0,3,30:1,0 0,3,36:1,0 0,6,95:2,0 0,3,36:1,0 0,3,34:1,0 0,3,32:1,0 15 169 . C <*> 0 . DP=55;I16=25,27,0,0,2228,100708,0,0,3097,184969,0,0,1180,28218,0,0;QS=43,0;MQSB=0.974135;MQ0F=0 PL:AD 0,3,44:1,0 0,6,74:2,0 0,3,43:1,0 0,3,48:1,0 0,0,0:0,0 0,3,36:1,0 0,3,43:1,0 0,3,47:1,0 0,3,47:1,0 0,6,74:2,0 0,3,33:1,0 0,3,42:1,0 0,6,71:2,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,3,43:1,0 0,0,0:0,0 0,3,38:1,0 0,6,71:2,0 0,6,67:2,0 0,3,35:1,0 0,0,0:0,0 0,3,60:1,0 0,3,42:1,0 0,0,0:0,0 0,3,45:1,0 0,3,40:1,0 0,3,39:1,0 0,3,41:1,0 0,3,42:1,0 0,6,70:2,0 0,3,33:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,3,38:1,0 0,3,45:1,0 0,0,0:0,0 0,3,47:1,0 0,9,114:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,39:1,0 0,6,95:2,0 0,3,42:1,0 0,3,38:1,0 0,3,37:1,0 15 170 . A <*> 0 . DP=55;I16=25,27,0,0,2100,90276,0,0,3097,184969,0,0,1193,28641,0,0;QS=43,0;MQSB=0.974135;MQ0F=0 PL:AD 0,3,40:1,0 0,6,72:2,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,3,37:1,0 0,3,43:1,0 0,3,47:1,0 0,3,47:1,0 0,6,79:2,0 0,3,32:1,0 0,3,37:1,0 0,6,67:2,0 0,3,36:1,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,0,0:0,0 0,3,30:1,0 0,6,67:2,0 0,6,56:2,0 0,3,34:1,0 0,0,0:0,0 0,3,60:1,0 0,3,37:1,0 0,0,0:0,0 0,3,45:1,0 0,3,43:1,0 0,3,36:1,0 0,3,38:1,0 0,3,42:1,0 0,6,68:2,0 0,3,42:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,32:1,0 0,3,45:1,0 0,0,0:0,0 0,3,41:1,0 0,9,100:3,0 0,3,60:1,0 0,3,44:1,0 0,3,35:1,0 0,3,36:1,0 0,6,95:2,0 0,3,39:1,0 0,3,34:1,0 0,3,32:1,0 15 171 . G <*> 0 . DP=55;I16=25,27,0,0,2226,101130,0,0,3097,184969,0,0,1206,29090,0,0;QS=43,0;MQSB=0.974135;MQ0F=0 PL:AD 0,3,41:1,0 0,6,80:2,0 0,3,42:1,0 0,3,45:1,0 0,0,0:0,0 0,3,39:1,0 0,3,44:1,0 0,3,46:1,0 0,3,46:1,0 0,6,79:2,0 0,3,39:1,0 0,3,31:1,0 0,6,69:2,0 0,3,39:1,0 0,3,43:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,0,0:0,0 0,3,40:1,0 0,6,72:2,0 0,6,60:2,0 0,3,36:1,0 0,0,0:0,0 0,3,60:1,0 0,3,28:1,0 0,0,0:0,0 0,3,42:1,0 0,3,32:1,0 0,3,38:1,0 0,3,43:1,0 0,3,43:1,0 0,6,75:2,0 0,3,44:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,3,40:1,0 0,3,43:1,0 0,0,0:0,0 0,3,46:1,0 0,9,114:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,42:1,0 0,6,95:2,0 0,3,40:1,0 0,3,40:1,0 0,3,40:1,0 15 172 . T <*> 0 . DP=56;I16=26,27,0,0,2007,81789,0,0,3157,188569,0,0,1218,29514,0,0;QS=43,0;MQSB=0.973606;MQ0F=0 PL:AD 0,3,39:1,0 0,6,63:2,0 0,3,36:1,0 0,3,40:1,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,3,45:1,0 0,3,44:1,0 0,6,76:2,0 0,3,25:1,0 0,6,59:2,0 0,6,67:2,0 0,3,33:1,0 0,3,40:1,0 0,0,0:0,0 0,3,41:1,0 0,3,41:1,0 0,0,0:0,0 0,3,28:1,0 0,6,64:2,0 0,6,50:2,0 0,3,32:1,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,38:1,0 0,3,36:1,0 0,3,32:1,0 0,3,36:1,0 0,3,36:1,0 0,6,62:2,0 0,3,43:1,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,30:1,0 0,3,43:1,0 0,0,0:0,0 0,3,40:1,0 0,9,100:3,0 0,3,60:1,0 0,3,43:1,0 0,3,35:1,0 0,3,34:1,0 0,6,94:2,0 0,3,38:1,0 0,3,32:1,0 0,3,30:1,0 15 173 . G <*> 0 . DP=57;I16=26,28,0,0,2285,101349,0,0,3217,192169,0,0,1228,29810,0,0;QS=43,0;MQSB=0.974993;MQ0F=0 PL:AD 0,3,43:1,0 0,6,76:2,0 0,3,41:1,0 0,3,44:1,0 0,0,0:0,0 0,3,36:1,0 0,3,44:1,0 0,6,76:2,0 0,3,46:1,0 0,6,81:2,0 0,3,38:1,0 0,6,75:2,0 0,6,67:2,0 0,3,38:1,0 0,3,44:1,0 0,0,0:0,0 0,3,40:1,0 0,3,45:1,0 0,0,0:0,0 0,3,39:1,0 0,6,70:2,0 0,6,63:2,0 0,3,37:1,0 0,0,0:0,0 0,3,60:1,0 0,3,38:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,3,38:1,0 0,3,40:1,0 0,3,38:1,0 0,6,78:2,0 0,3,44:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,3,39:1,0 0,3,44:1,0 0,0,0:0,0 0,3,40:1,0 0,9,112:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,42:1,0 0,6,90:2,0 0,3,41:1,0 0,3,40:1,0 0,3,38:1,0 15 174 . A <*> 0 . DP=59;I16=26,28,0,0,2072,85654,0,0,3217,192169,0,0,1238,30076,0,0;QS=43,0;MQSB=0.974993;MQ0F=0 PL:AD 0,3,37:1,0 0,6,64:2,0 0,3,36:1,0 0,3,39:1,0 0,0,0:0,0 0,3,32:1,0 0,3,42:1,0 0,6,71:2,0 0,3,43:1,0 0,6,70:2,0 0,3,33:1,0 0,6,62:2,0 0,6,56:2,0 0,3,24:1,0 0,3,37:1,0 0,0,0:0,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,3,59:1,0 0,6,60:2,0 0,6,56:2,0 0,3,29:1,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,41:1,0 0,3,42:1,0 0,3,30:1,0 0,3,37:1,0 0,3,37:1,0 0,6,63:2,0 0,3,39:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,3,39:1,0 0,9,122:3,0 0,3,60:1,0 0,3,42:1,0 0,3,31:1,0 0,3,36:1,0 0,6,95:2,0 0,3,36:1,0 0,3,32:1,0 0,3,32:1,0 15 175 . C <*> 0 . DP=60;I16=26,29,0,0,2411,113199,0,0,3277,195769,0,0,1248,30362,0,0;QS=44,0;MQSB=0.976271;MQ0F=0 PL:AD 0,3,44:1,0 0,6,74:2,0 0,3,41:1,0 0,3,44:1,0 0,0,0:0,0 0,3,37:1,0 0,3,40:1,0 0,6,79:2,0 0,3,47:1,0 0,6,84:2,0 0,3,35:1,0 0,6,75:2,0 0,6,70:2,0 0,3,39:1,0 0,3,42:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,0,0:0,0 0,3,60:1,0 0,6,70:2,0 0,6,67:2,0 0,3,36:1,0 0,0,0:0,0 0,3,60:1,0 0,3,36:1,0 0,0,0:0,0 0,3,45:1,0 0,3,41:1,0 0,3,39:1,0 0,3,41:1,0 0,3,38:1,0 0,6,76:2,0 0,3,44:1,0 0,0,0:0,0 0,3,38:1,0 0,3,28:1,0 0,0,0:0,0 0,3,44:1,0 0,3,38:1,0 0,3,45:1,0 0,0,0:0,0 0,3,41:1,0 0,9,136:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,40:1,0 0,6,95:2,0 0,3,41:1,0 0,3,38:1,0 0,3,38:1,0 15 176 . A <*> 0 . DP=60;I16=26,29,0,0,2166,92394,0,0,3277,195769,0,0,1259,30669,0,0;QS=44,0;MQSB=0.976271;MQ0F=0 PL:AD 0,3,38:1,0 0,6,69:2,0 0,3,32:1,0 0,3,37:1,0 0,0,0:0,0 0,3,37:1,0 0,3,43:1,0 0,6,77:2,0 0,3,43:1,0 0,6,76:2,0 0,3,33:1,0 0,6,61:2,0 0,6,61:2,0 0,3,31:1,0 0,3,38:1,0 0,0,0:0,0 0,3,42:1,0 0,3,43:1,0 0,0,0:0,0 0,3,60:1,0 0,6,69:2,0 0,6,57:2,0 0,3,21:1,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,3,31:1,0 0,3,38:1,0 0,3,43:1,0 0,6,65:2,0 0,3,42:1,0 0,0,0:0,0 0,3,32:1,0 0,3,30:1,0 0,0,0:0,0 0,3,39:1,0 0,3,32:1,0 0,3,39:1,0 0,0,0:0,0 0,3,35:1,0 0,9,123:3,0 0,3,60:1,0 0,3,42:1,0 0,3,29:1,0 0,3,36:1,0 0,6,95:2,0 0,3,35:1,0 0,3,35:1,0 0,3,32:1,0 15 177 . T <*> 0 . DP=60;I16=26,29,0,0,2230,96748,0,0,3277,195769,0,0,1268,30898,0,0;QS=44,0;MQSB=0.976271;MQ0F=0 PL:AD 0,3,40:1,0 0,6,69:2,0 0,3,34:1,0 0,3,41:1,0 0,0,0:0,0 0,3,40:1,0 0,3,42:1,0 0,6,78:2,0 0,3,45:1,0 0,6,79:2,0 0,3,33:1,0 0,6,66:2,0 0,6,66:2,0 0,3,37:1,0 0,3,38:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,60:1,0 0,6,65:2,0 0,6,54:2,0 0,3,32:1,0 0,0,0:0,0 0,3,60:1,0 0,3,36:1,0 0,0,0:0,0 0,3,43:1,0 0,3,42:1,0 0,3,33:1,0 0,3,37:1,0 0,3,41:1,0 0,6,65:2,0 0,3,43:1,0 0,0,0:0,0 0,3,32:1,0 0,3,30:1,0 0,0,0:0,0 0,3,41:1,0 0,3,31:1,0 0,3,43:1,0 0,0,0:0,0 0,3,40:1,0 0,9,126:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,35:1,0 0,6,95:2,0 0,3,37:1,0 0,3,33:1,0 0,3,32:1,0 15 178 . T <*> 0 . DP=61;I16=26,30,0,0,2125,87125,0,0,3337,199369,0,0,1275,31049,0,0;QS=45,0;MQSB=0.977451;MQ0F=0 PL:AD 0,3,34:1,0 0,6,65:2,0 0,3,24:1,0 0,3,35:1,0 0,0,0:0,0 0,3,33:1,0 0,3,42:1,0 0,6,70:2,0 0,3,42:1,0 0,6,69:2,0 0,3,32:1,0 0,6,63:2,0 0,6,60:2,0 0,3,31:1,0 0,3,36:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,60:1,0 0,6,64:2,0 0,6,57:2,0 0,3,29:1,0 0,3,28:1,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,41:1,0 0,3,35:1,0 0,3,30:1,0 0,3,36:1,0 0,3,42:1,0 0,6,65:2,0 0,3,39:1,0 0,0,0:0,0 0,3,34:1,0 0,3,26:1,0 0,0,0:0,0 0,3,37:1,0 0,3,33:1,0 0,3,37:1,0 0,0,0:0,0 0,3,33:1,0 0,9,122:3,0 0,3,60:1,0 0,3,41:1,0 0,3,37:1,0 0,3,36:1,0 0,6,95:2,0 0,3,33:1,0 0,3,34:1,0 0,3,33:1,0 15 179 . A <*> 0 . DP=62;I16=26,31,0,0,2165,88791,0,0,3397,202969,0,0,1281,31123,0,0;QS=45,0;MQSB=0.978543;MQ0F=0 PL:AD 0,3,36:1,0 0,6,61:2,0 0,3,36:1,0 0,3,37:1,0 0,0,0:0,0 0,3,31:1,0 0,3,41:1,0 0,6,76:2,0 0,3,43:1,0 0,6,76:2,0 0,6,59:2,0 0,6,61:2,0 0,6,59:2,0 0,3,31:1,0 0,3,39:1,0 0,0,0:0,0 0,3,37:1,0 0,3,37:1,0 0,0,0:0,0 0,3,60:1,0 0,6,61:2,0 0,6,54:2,0 0,3,31:1,0 0,3,29:1,0 0,3,60:1,0 0,3,32:1,0 0,0,0:0,0 0,3,42:1,0 0,3,41:1,0 0,3,31:1,0 0,3,34:1,0 0,3,41:1,0 0,6,62:2,0 0,3,42:1,0 0,0,0:0,0 0,3,31:1,0 0,3,29:1,0 0,0,0:0,0 0,3,39:1,0 0,3,31:1,0 0,3,39:1,0 0,0,0:0,0 0,3,39:1,0 0,9,122:3,0 0,3,60:1,0 0,3,42:1,0 0,3,30:1,0 0,3,34:1,0 0,6,94:2,0 0,3,34:1,0 0,3,34:1,0 0,3,31:1,0 15 180 . T <*> 0 . DP=63;I16=27,31,0,0,2170,87584,0,0,3457,206569,0,0,1287,31173,0,0;QS=45,0;MQSB=0.9781;MQ0F=0 PL:AD 0,3,34:1,0 0,6,70:2,0 0,3,33:1,0 0,3,33:1,0 0,0,0:0,0 0,3,26:1,0 0,3,42:1,0 0,6,69:2,0 0,3,42:1,0 0,6,63:2,0 0,6,60:2,0 0,6,63:2,0 0,9,92:3,0 0,3,30:1,0 0,3,35:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,60:1,0 0,6,62:2,0 0,6,56:2,0 0,3,30:1,0 0,3,31:1,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,41:1,0 0,3,43:1,0 0,3,30:1,0 0,3,37:1,0 0,3,42:1,0 0,6,62:2,0 0,3,42:1,0 0,0,0:0,0 0,3,32:1,0 0,3,31:1,0 0,0,0:0,0 0,3,35:1,0 0,3,31:1,0 0,3,34:1,0 0,0,0:0,0 0,3,38:1,0 0,9,115:3,0 0,3,60:1,0 0,3,41:1,0 0,3,37:1,0 0,3,35:1,0 0,6,95:2,0 0,3,31:1,0 0,3,33:1,0 0,3,32:1,0 15 181 . A <*> 0 . DP=63;I16=27,31,0,0,2165,87491,0,0,3457,206569,0,0,1286,30856,0,0;QS=45,0;MQSB=0.9781;MQ0F=0 PL:AD 0,3,38:1,0 0,6,64:2,0 0,3,35:1,0 0,3,36:1,0 0,0,0:0,0 0,3,33:1,0 0,3,42:1,0 0,6,67:2,0 0,3,43:1,0 0,6,74:2,0 0,6,60:2,0 0,6,61:2,0 0,9,90:3,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,3,37:1,0 0,3,36:1,0 0,0,0:0,0 0,3,60:1,0 0,6,58:2,0 0,6,50:2,0 0,3,31:1,0 0,3,29:1,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,3,30:1,0 0,3,33:1,0 0,3,37:1,0 0,6,62:2,0 0,3,36:1,0 0,0,0:0,0 0,3,31:1,0 0,3,28:1,0 0,0,0:0,0 0,3,39:1,0 0,3,31:1,0 0,3,38:1,0 0,0,0:0,0 0,3,36:1,0 0,9,121:3,0 0,3,60:1,0 0,3,42:1,0 0,3,30:1,0 0,3,34:1,0 0,6,94:2,0 0,3,36:1,0 0,3,34:1,0 0,3,31:1,0 15 182 . T <*> 0 . DP=65;I16=28,31,0,0,2261,94185,0,0,3517,210169,0,0,1284,30528,0,0;QS=46,0;MQSB=0.977672;MQ0F=0 PL:AD 0,3,37:1,0 0,6,90:2,0 0,3,34:1,0 0,3,39:1,0 0,0,0:0,0 0,3,34:1,0 0,3,42:1,0 0,6,75:2,0 0,3,37:1,0 0,6,71:2,0 0,6,63:2,0 0,6,62:2,0 0,9,93:3,0 0,3,33:1,0 0,3,38:1,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,3,24:1,0 0,3,60:1,0 0,6,66:2,0 0,6,55:2,0 0,3,31:1,0 0,3,31:1,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,38:1,0 0,3,36:1,0 0,3,32:1,0 0,3,38:1,0 0,3,34:1,0 0,6,64:2,0 0,3,37:1,0 0,0,0:0,0 0,3,32:1,0 0,3,27:1,0 0,0,0:0,0 0,3,37:1,0 0,3,31:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,9,124:3,0 0,3,60:1,0 0,3,41:1,0 0,3,32:1,0 0,3,35:1,0 0,6,95:2,0 0,3,35:1,0 0,3,32:1,0 0,3,32:1,0 15 183 . C <*> 0 . DP=65;I16=28,31,0,0,2572,121896,0,0,3517,210169,0,0,1282,30190,0,0;QS=46,0;MQSB=0.977672;MQ0F=0 PL:AD 0,3,42:1,0 0,6,91:2,0 0,3,41:1,0 0,3,47:1,0 0,0,0:0,0 0,3,24:1,0 0,3,43:1,0 0,6,83:2,0 0,3,46:1,0 0,6,79:2,0 0,6,70:2,0 0,6,75:2,0 0,9,109:3,0 0,3,42:1,0 0,3,39:1,0 0,0,0:0,0 0,3,44:1,0 0,3,39:1,0 0,3,34:1,0 0,3,60:1,0 0,6,72:2,0 0,6,62:2,0 0,3,36:1,0 0,3,38:1,0 0,3,60:1,0 0,3,42:1,0 0,0,0:0,0 0,3,45:1,0 0,3,38:1,0 0,3,39:1,0 0,3,42:1,0 0,3,43:1,0 0,6,76:2,0 0,3,39:1,0 0,0,0:0,0 0,3,38:1,0 0,3,30:1,0 0,0,0:0,0 0,3,41:1,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,9,134:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,40:1,0 0,6,96:2,0 0,3,36:1,0 0,3,39:1,0 0,3,38:1,0 15 184 . A <*> 0 . DP=65;I16=28,31,0,0,2283,96561,0,0,3517,210169,0,0,1278,29794,0,0;QS=46,0;MQSB=0.977672;MQ0F=0 PL:AD 0,3,37:1,0 0,6,90:2,0 0,3,32:1,0 0,3,36:1,0 0,0,0:0,0 0,3,34:1,0 0,3,39:1,0 0,6,71:2,0 0,3,38:1,0 0,6,74:2,0 0,6,65:2,0 0,6,63:2,0 0,9,92:3,0 0,3,31:1,0 0,3,37:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,3,30:1,0 0,3,60:1,0 0,6,69:2,0 0,6,57:2,0 0,3,30:1,0 0,3,32:1,0 0,3,60:1,0 0,3,31:1,0 0,0,0:0,0 0,3,38:1,0 0,3,41:1,0 0,3,29:1,0 0,3,39:1,0 0,3,43:1,0 0,6,62:2,0 0,3,36:1,0 0,0,0:0,0 0,3,32:1,0 0,3,27:1,0 0,0,0:0,0 0,3,36:1,0 0,3,32:1,0 0,3,35:1,0 0,0,0:0,0 0,3,38:1,0 0,9,121:3,0 0,3,60:1,0 0,3,41:1,0 0,3,30:1,0 0,3,36:1,0 0,6,95:2,0 0,3,33:1,0 0,3,33:1,0 0,3,31:1,0 15 185 . C <*> 0 . DP=65;I16=28,31,0,0,2582,123274,0,0,3517,210169,0,0,1273,29393,0,0;QS=46,0;MQSB=0.977672;MQ0F=0 PL:AD 0,3,44:1,0 0,6,95:2,0 0,3,41:1,0 0,3,34:1,0 0,0,0:0,0 0,3,34:1,0 0,3,43:1,0 0,6,73:2,0 0,3,46:1,0 0,6,76:2,0 0,6,75:2,0 0,6,77:2,0 0,9,108:3,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,3,35:1,0 0,3,60:1,0 0,6,70:2,0 0,6,62:2,0 0,3,33:1,0 0,3,40:1,0 0,3,60:1,0 0,3,43:1,0 0,0,0:0,0 0,3,45:1,0 0,3,40:1,0 0,3,38:1,0 0,3,42:1,0 0,3,42:1,0 0,6,77:2,0 0,3,38:1,0 0,0,0:0,0 0,3,38:1,0 0,3,30:1,0 0,0,0:0,0 0,3,41:1,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,9,132:3,0 0,3,60:1,0 0,3,44:1,0 0,3,37:1,0 0,3,40:1,0 0,6,95:2,0 0,3,41:1,0 0,3,39:1,0 0,3,38:1,0 15 186 . A <*> 0 . DP=67;I16=30,31,0,0,2358,99810,0,0,3637,217369,0,0,1266,28940,0,0;QS=48,0;MQSB=0.976859;MQ0F=0 PL:AD 0,3,34:1,0 0,6,90:2,0 0,3,31:1,0 0,3,36:1,0 0,3,22:1,0 0,3,32:1,0 0,3,41:1,0 0,6,74:2,0 0,3,43:1,0 0,6,70:2,0 0,6,65:2,0 0,6,68:2,0 0,9,95:3,0 0,3,34:1,0 0,3,34:1,0 0,0,0:0,0 0,3,43:1,0 0,3,40:1,0 0,3,32:1,0 0,3,60:1,0 0,6,64:2,0 0,6,55:2,0 0,3,30:1,0 0,3,31:1,0 0,3,60:1,0 0,3,34:1,0 0,3,25:1,0 0,3,42:1,0 0,3,42:1,0 0,3,33:1,0 0,3,39:1,0 0,3,43:1,0 0,6,65:2,0 0,3,42:1,0 0,0,0:0,0 0,3,33:1,0 0,3,24:1,0 0,0,0:0,0 0,3,34:1,0 0,3,32:1,0 0,3,39:1,0 0,0,0:0,0 0,3,38:1,0 0,9,123:3,0 0,3,60:1,0 0,3,42:1,0 0,3,32:1,0 0,3,36:1,0 0,6,95:2,0 0,3,32:1,0 0,3,36:1,0 0,3,32:1,0 15 187 . A <*> 0 . DP=68;I16=31,31,0,0,2362,97544,0,0,3697,220969,0,0,1260,28490,0,0;QS=48,0;MQSB=0.976472;MQ0F=0 PL:AD 0,3,36:1,0 0,6,90:2,0 0,3,36:1,0 0,3,43:1,0 0,3,36:1,0 0,3,38:1,0 0,3,44:1,0 0,6,66:2,0 0,3,37:1,0 0,6,61:2,0 0,6,67:2,0 0,6,66:2,0 0,9,91:3,0 0,3,31:1,0 0,3,37:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,3,34:1,0 0,3,60:1,0 0,6,65:2,0 0,6,60:2,0 0,3,30:1,0 0,6,65:2,0 0,3,60:1,0 0,3,31:1,0 0,3,33:1,0 0,3,38:1,0 0,3,43:1,0 0,3,29:1,0 0,3,40:1,0 0,3,40:1,0 0,6,64:2,0 0,3,36:1,0 0,0,0:0,0 0,3,34:1,0 0,3,18:1,0 0,0,0:0,0 0,3,37:1,0 0,3,34:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,9,121:3,0 0,3,32:1,0 0,3,41:1,0 0,3,30:1,0 0,3,39:1,0 0,6,95:2,0 0,3,35:1,0 0,3,35:1,0 0,3,34:1,0 15 188 . C <*> 0 . DP=69;I16=32,31,0,0,2677,124159,0,0,3757,224569,0,0,1254,28048,0,0;QS=49,0;MQSB=0.976097;MQ0F=0 PL:AD 0,3,43:1,0 0,6,95:2,0 0,3,40:1,0 0,3,42:1,0 0,3,39:1,0 0,3,38:1,0 0,3,41:1,0 0,6,78:2,0 0,3,47:1,0 0,6,81:2,0 0,6,74:2,0 0,6,77:2,0 0,9,110:3,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,3,43:1,0 0,3,44:1,0 0,3,37:1,0 0,3,60:1,0 0,6,70:2,0 0,6,47:2,0 0,3,33:1,0 0,6,71:2,0 0,3,60:1,0 0,3,35:1,0 0,3,34:1,0 0,3,44:1,0 0,3,43:1,0 0,3,38:1,0 0,3,42:1,0 0,3,43:1,0 0,6,76:2,0 0,3,45:1,0 0,0,0:0,0 0,3,38:1,0 0,3,30:1,0 0,0,0:0,0 0,3,40:1,0 0,3,38:1,0 0,3,40:1,0 0,3,21:1,0 0,3,40:1,0 0,9,126:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,40:1,0 0,6,95:2,0 0,3,37:1,0 0,3,30:1,0 0,3,38:1,0 15 189 . C <*> 0 . DP=69;I16=32,31,0,0,2720,127270,0,0,3757,224569,0,0,1248,27618,0,0;QS=49,0;MQSB=0.976097;MQ0F=0 PL:AD 0,3,42:1,0 0,6,95:2,0 0,3,38:1,0 0,3,43:1,0 0,3,31:1,0 0,3,37:1,0 0,3,44:1,0 0,6,73:2,0 0,3,46:1,0 0,6,78:2,0 0,6,78:2,0 0,6,79:2,0 0,9,111:3,0 0,3,42:1,0 0,3,33:1,0 0,0,0:0,0 0,3,44:1,0 0,3,45:1,0 0,3,37:1,0 0,3,60:1,0 0,6,69:2,0 0,6,60:2,0 0,3,37:1,0 0,6,77:2,0 0,3,60:1,0 0,3,43:1,0 0,3,38:1,0 0,3,44:1,0 0,3,40:1,0 0,3,40:1,0 0,3,42:1,0 0,3,44:1,0 0,6,73:2,0 0,3,44:1,0 0,0,0:0,0 0,3,34:1,0 0,3,31:1,0 0,0,0:0,0 0,3,44:1,0 0,3,34:1,0 0,3,40:1,0 0,3,33:1,0 0,3,40:1,0 0,9,134:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,3,41:1,0 0,6,96:2,0 0,3,40:1,0 0,3,37:1,0 0,3,34:1,0 15 190 . T <*> 0 . DP=71;I16=33,32,0,0,2577,111063,0,0,3877,231769,0,0,1240,27154,0,0;QS=49,0;MQSB=0.976835;MQ0F=0 PL:AD 0,3,37:1,0 0,6,90:2,0 0,3,34:1,0 0,3,36:1,0 0,3,39:1,0 0,3,27:1,0 0,3,45:1,0 0,6,66:2,0 0,3,42:1,0 0,6,68:2,0 0,6,70:2,0 0,6,69:2,0 0,9,96:3,0 0,3,33:1,0 0,3,38:1,0 0,0,0:0,0 0,3,45:1,0 0,3,45:1,0 0,3,36:1,0 0,3,60:1,0 0,6,65:2,0 0,6,60:2,0 0,3,32:1,0 0,6,71:2,0 0,3,60:1,0 0,3,33:1,0 0,3,34:1,0 0,3,41:1,0 0,3,37:1,0 0,3,32:1,0 0,3,40:1,0 0,3,44:1,0 0,6,68:2,0 0,3,42:1,0 0,0,0:0,0 0,6,67:2,0 0,3,22:1,0 0,0,0:0,0 0,3,38:1,0 0,3,35:1,0 0,3,35:1,0 0,3,35:1,0 0,3,39:1,0 0,9,123:3,0 0,3,60:1,0 0,3,41:1,0 0,3,37:1,0 0,6,67:2,0 0,6,97:2,0 0,3,32:1,0 0,3,37:1,0 0,3,36:1,0 15 191 . C <*> 0 . DP=73;I16=35,32,0,0,2846,131780,0,0,3997,238969,0,0,1232,26660,0,0;QS=50,0;MQSB=0.976162;MQ0F=0 PL:AD 0,3,42:1,0 0,6,90:2,0 0,3,41:1,0 0,3,40:1,0 0,3,39:1,0 0,3,37:1,0 0,3,39:1,0 0,6,77:2,0 0,3,41:1,0 0,6,66:2,0 0,6,78:2,0 0,6,77:2,0 0,9,109:3,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,3,44:1,0 0,3,45:1,0 0,3,37:1,0 0,3,60:1,0 0,6,67:2,0 0,6,65:2,0 0,3,29:1,0 0,6,77:2,0 0,3,60:1,0 0,3,43:1,0 0,3,38:1,0 0,3,45:1,0 0,3,31:1,0 0,3,38:1,0 0,3,43:1,0 0,3,43:1,0 0,6,78:2,0 0,3,44:1,0 0,3,20:1,0 0,6,74:2,0 0,3,44:1,0 0,0,0:0,0 0,3,42:1,0 0,3,38:1,0 0,3,38:1,0 0,3,31:1,0 0,3,39:1,0 0,9,133:3,0 0,3,60:1,0 0,3,43:1,0 0,3,37:1,0 0,6,70:2,0 0,6,96:2,0 0,3,40:1,0 0,6,63:2,0 0,3,37:1,0 15 192 . A <*> 0 . DP=74;I16=35,32,0,0,2776,126286,0,0,3997,238969,0,0,1226,26240,0,0;QS=50,0;MQSB=0.976162;MQ0F=0 PL:AD 0,3,40:1,0 0,6,86:2,0 0,3,36:1,0 0,3,39:1,0 0,3,37:1,0 0,3,34:1,0 0,3,42:1,0 0,6,79:2,0 0,3,46:1,0 0,6,75:2,0 0,6,71:2,0 0,6,69:2,0 0,9,101:3,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,3,43:1,0 0,3,43:1,0 0,3,33:1,0 0,3,60:1,0 0,6,65:2,0 0,6,56:2,0 0,3,36:1,0 0,6,71:2,0 0,3,60:1,0 0,3,37:1,0 0,3,33:1,0 0,3,44:1,0 0,3,60:1,0 0,3,36:1,0 0,3,39:1,0 0,3,43:1,0 0,6,68:2,0 0,3,44:1,0 0,3,28:1,0 0,6,66:2,0 0,3,43:1,0 0,0,0:0,0 0,3,41:1,0 0,3,32:1,0 0,3,40:1,0 0,3,38:1,0 0,3,46:1,0 0,9,130:3,0 0,3,60:1,0 0,3,43:1,0 0,3,36:1,0 0,6,62:2,0 0,6,96:2,0 0,3,37:1,0 0,6,58:2,0 0,3,32:1,0 15 193 . G <*> 0 . DP=75;I16=36,32,0,0,2939,138563,0,0,4057,242569,0,0,1220,25896,0,0;QS=51,0;MQSB=0.97584;MQ0F=0 PL:AD 0,3,43:1,0 0,6,91:2,0 0,3,34:1,0 0,3,39:1,0 0,3,39:1,0 0,3,34:1,0 0,3,42:1,0 0,6,74:2,0 0,3,45:1,0 0,6,77:2,0 0,6,79:2,0 0,6,71:2,0 0,9,108:3,0 0,3,38:1,0 0,3,43:1,0 0,3,28:1,0 0,3,45:1,0 0,3,45:1,0 0,3,40:1,0 0,3,60:1,0 0,6,70:2,0 0,6,58:2,0 0,3,35:1,0 0,6,76:2,0 0,3,60:1,0 0,3,37:1,0 0,3,38:1,0 0,3,42:1,0 0,3,60:1,0 0,3,38:1,0 0,3,42:1,0 0,3,44:1,0 0,6,76:2,0 0,3,44:1,0 0,3,28:1,0 0,6,75:2,0 0,3,41:1,0 0,0,0:0,0 0,3,43:1,0 0,3,40:1,0 0,3,36:1,0 0,3,39:1,0 0,3,46:1,0 0,9,132:3,0 0,3,60:1,0 0,3,42:1,0 0,3,37:1,0 0,6,73:2,0 0,6,93:2,0 0,3,40:1,0 0,6,72:2,0 0,3,39:1,0 15 194 . A <*> 0 . DP=75;I16=36,32,0,0,2646,112608,0,0,4057,242569,0,0,1213,25531,0,0;QS=51,0;MQSB=0.97584;MQ0F=0 PL:AD 0,3,36:1,0 0,6,90:2,0 0,3,40:1,0 0,3,36:1,0 0,3,36:1,0 0,3,38:1,0 0,3,40:1,0 0,6,74:2,0 0,3,42:1,0 0,6,74:2,0 0,6,66:2,0 0,6,66:2,0 0,9,95:3,0 0,3,34:1,0 0,3,37:1,0 0,3,28:1,0 0,3,42:1,0 0,3,40:1,0 0,3,33:1,0 0,3,60:1,0 0,6,63:2,0 0,6,56:2,0 0,3,32:1,0 0,6,68:2,0 0,3,60:1,0 0,3,33:1,0 0,3,31:1,0 0,3,30:1,0 0,3,60:1,0 0,3,33:1,0 0,3,38:1,0 0,3,42:1,0 0,6,66:2,0 0,3,42:1,0 0,3,18:1,0 0,6,65:2,0 0,3,36:1,0 0,0,0:0,0 0,3,34:1,0 0,3,33:1,0 0,3,42:1,0 0,3,36:1,0 0,3,44:1,0 0,9,124:3,0 0,3,60:1,0 0,3,40:1,0 0,3,32:1,0 0,6,64:2,0 0,6,95:2,0 0,3,33:1,0 0,6,53:2,0 0,3,33:1,0 15 195 . A <*> 0 . DP=77;I16=38,32,0,0,2724,116142,0,0,4177,249769,0,0,1204,25148,0,0;QS=52,0;MQSB=0.975224;MQ0F=0 PL:AD 0,3,36:1,0 0,6,91:2,0 0,3,33:1,0 0,3,36:1,0 0,3,31:1,0 0,3,31:1,0 0,3,38:1,0 0,6,74:2,0 0,3,42:1,0 0,6,70:2,0 0,6,67:2,0 0,6,69:2,0 0,9,98:3,0 0,3,34:1,0 0,3,38:1,0 0,3,31:1,0 0,3,43:1,0 0,3,40:1,0 0,6,56:2,0 0,3,60:1,0 0,6,66:2,0 0,6,54:2,0 0,3,30:1,0 0,6,69:2,0 0,3,60:1,0 0,3,33:1,0 0,3,34:1,0 0,3,42:1,0 0,3,60:1,0 0,3,33:1,0 0,3,40:1,0 0,3,43:1,0 0,6,68:2,0 0,3,42:1,0 0,3,26:1,0 0,6,66:2,0 0,3,28:1,0 0,3,20:1,0 0,3,32:1,0 0,3,32:1,0 0,3,42:1,0 0,3,39:1,0 0,3,44:1,0 0,9,124:3,0 0,3,60:1,0 0,3,40:1,0 0,3,32:1,0 0,6,69:2,0 0,6,93:2,0 0,3,35:1,0 0,6,64:2,0 0,3,33:1,0 15 196 . A <*> 0 . DP=78;I16=39,32,0,0,2730,115996,0,0,4237,253369,0,0,1196,24800,0,0;QS=52,0;MQSB=0.974929;MQ0F=0 PL:AD 0,3,36:1,0 0,6,94:2,0 0,3,31:1,0 0,3,34:1,0 0,3,18:1,0 0,3,31:1,0 0,3,44:1,0 0,6,74:2,0 0,3,42:1,0 0,6,72:2,0 0,6,66:2,0 0,6,67:2,0 0,9,96:3,0 0,3,31:1,0 0,3,38:1,0 0,3,31:1,0 0,3,40:1,0 0,3,44:1,0 0,6,58:2,0 0,3,59:1,0 0,6,65:2,0 0,6,58:2,0 0,3,30:1,0 0,6,68:2,0 0,3,60:1,0 0,3,32:1,0 0,3,33:1,0 0,3,41:1,0 0,3,60:1,0 0,3,29:1,0 0,3,40:1,0 0,3,43:1,0 0,6,65:2,0 0,3,37:1,0 0,3,37:1,0 0,6,58:2,0 0,3,22:1,0 0,3,29:1,0 0,3,33:1,0 0,3,34:1,0 0,3,38:1,0 0,3,39:1,0 0,3,38:1,0 0,12,143:4,0 0,3,60:1,0 0,3,39:1,0 0,3,30:1,0 0,6,69:2,0 0,6,96:2,0 0,3,35:1,0 0,6,65:2,0 0,3,34:1,0 15 197 . C <*> 0 . DP=79;I16=40,31,0,0,3052,142186,0,0,4237,253369,0,0,1164,23910,0,0;QS=51,0;MQSB=0.973476;MQ0F=0 PL:AD 0,3,43:1,0 0,6,90:2,0 0,3,37:1,0 0,3,44:1,0 0,3,34:1,0 0,3,37:1,0 0,3,39:1,0 0,6,85:2,0 0,3,46:1,0 0,6,74:2,0 0,6,74:2,0 0,6,74:2,0 0,9,113:3,0 0,3,40:1,0 0,3,42:1,0 0,3,37:1,0 0,3,44:1,0 0,3,44:1,0 0,6,68:2,0 0,3,60:1,0 0,6,69:2,0 0,6,66:2,0 0,3,32:1,0 0,6,81:2,0 0,3,60:1,0 0,3,40:1,0 0,3,38:1,0 0,3,44:1,0 0,3,60:1,0 0,3,37:1,0 0,3,42:1,0 0,3,43:1,0 0,9,103:3,0 0,3,44:1,0 0,3,37:1,0 0,6,75:2,0 0,0,0:0,0 0,3,34:1,0 0,3,43:1,0 0,3,38:1,0 0,3,39:1,0 0,3,37:1,0 0,3,47:1,0 0,12,159:4,0 0,3,60:1,0 0,3,42:1,0 0,3,37:1,0 0,6,71:2,0 0,6,93:2,0 0,3,40:1,0 0,6,63:2,0 0,3,36:1,0 15 198 . C A,<*> 0 . DP=79;I16=40,31,0,1,3061,142883,35,1225,4237,253369,60,3600,1148,23262,25,625;QS=51,1,0;SGB=-0.627953;RPB=1;MQB=1;MQSB=0.974642;BQB=1;MQ0F=0 PL:AD 0,3,44,3,44,44:1,0,0 0,6,95,6,95,95:2,0,0 0,3,39,3,39,39:1,0,0 0,3,43,3,43,43:1,0,0 0,3,34,3,34,34:1,0,0 0,3,37,3,37,37:1,0,0 0,3,41,3,41,41:1,0,0 0,6,87,6,87,87:2,0,0 0,3,46,3,46,46:1,0,0 0,6,76,6,76,76:2,0,0 0,6,80,6,80,80:2,0,0 0,6,78,6,78,78:2,0,0 0,9,112,9,112,112:3,0,0 0,3,41,3,41,41:1,0,0 35,3,0,35,3,35:0,1,0 0,3,33,3,33,33:1,0,0 0,3,44,3,44,44:1,0,0 0,3,45,3,45,45:1,0,0 0,6,69,6,69,69:2,0,0 0,3,60,3,60,60:1,0,0 0,6,70,6,70,70:2,0,0 0,6,57,6,57,57:2,0,0 0,3,37,3,37,37:1,0,0 0,6,79,6,79,79:2,0,0 0,3,60,3,60,60:1,0,0 0,3,42,3,42,42:1,0,0 0,3,39,3,39,39:1,0,0 0,3,44,3,44,44:1,0,0 0,3,60,3,60,60:1,0,0 0,3,39,3,39,39:1,0,0 0,3,41,3,41,41:1,0,0 0,3,44,3,44,44:1,0,0 0,9,98,9,98,98:3,0,0 0,3,40,3,40,40:1,0,0 0,3,38,3,38,38:1,0,0 0,6,72,6,72,72:2,0,0 0,3,29,3,29,29:1,0,0 0,3,34,3,34,34:1,0,0 0,3,43,3,43,43:1,0,0 0,3,34,3,34,34:1,0,0 0,3,44,3,44,44:1,0,0 0,3,36,3,36,36:1,0,0 0,3,47,3,47,47:1,0,0 0,12,163,12,163,163:4,0,0 0,3,60,3,60,60:1,0,0 0,3,41,3,41,41:1,0,0 0,3,37,3,37,37:1,0,0 0,6,73,6,73,73:2,0,0 0,6,96,6,96,96:2,0,0 0,3,40,3,40,40:1,0,0 0,6,67,6,67,67:2,0,0 0,3,33,3,33,33:1,0,0 15 199 . A <*> 0 . DP=79;I16=40,32,0,0,2797,119253,0,0,4297,256969,0,0,1158,23382,0,0;QS=52,0;MQSB=0.974642;MQ0F=0 PL:AD 0,3,37:1,0 0,6,90:2,0 0,3,41:1,0 0,3,37:1,0 0,3,36:1,0 0,3,39:1,0 0,3,43:1,0 0,6,75:2,0 0,3,42:1,0 0,6,78:2,0 0,6,66:2,0 0,6,64:2,0 0,9,92:3,0 0,3,31:1,0 0,3,37:1,0 0,3,31:1,0 0,3,40:1,0 0,3,44:1,0 0,6,60:2,0 0,3,60:1,0 0,6,64:2,0 0,6,55:2,0 0,3,30:1,0 0,6,66:2,0 0,3,60:1,0 0,3,32:1,0 0,3,33:1,0 0,3,40:1,0 0,3,60:1,0 0,3,30:1,0 0,3,39:1,0 0,3,43:1,0 0,9,88:3,0 0,3,40:1,0 0,3,38:1,0 0,6,62:2,0 0,3,36:1,0 0,3,37:1,0 0,3,38:1,0 0,3,32:1,0 0,3,41:1,0 0,3,40:1,0 0,3,43:1,0 0,12,147:4,0 0,3,60:1,0 0,3,26:1,0 0,3,30:1,0 0,6,65:2,0 0,6,89:2,0 0,3,27:1,0 0,6,61:2,0 0,3,32:1,0 15 200 . C <*> 0 . DP=79;I16=40,32,0,0,2920,129812,0,0,4297,256969,0,0,1143,22979,0,0;QS=52,0;MQSB=0.974642;MQ0F=0 PL:AD 0,3,43:1,0 0,6,91:2,0 0,3,27:1,0 0,3,35:1,0 0,3,40:1,0 0,3,34:1,0 0,3,39:1,0 0,6,81:2,0 0,3,46:1,0 0,6,79:2,0 0,6,81:2,0 0,6,76:2,0 0,9,113:3,0 0,3,41:1,0 0,3,42:1,0 0,3,38:1,0 0,3,44:1,0 0,3,44:1,0 0,6,68:2,0 0,3,60:1,0 0,6,65:2,0 0,6,66:2,0 0,3,37:1,0 0,6,81:2,0 0,3,60:1,0 0,3,33:1,0 0,3,38:1,0 0,3,36:1,0 0,3,60:1,0 0,3,26:1,0 0,3,42:1,0 0,3,43:1,0 0,9,95:3,0 0,3,37:1,0 0,3,35:1,0 0,6,63:2,0 0,3,19:1,0 0,3,37:1,0 0,3,35:1,0 0,3,38:1,0 0,3,36:1,0 0,3,38:1,0 0,3,39:1,0 0,12,143:4,0 0,3,60:1,0 0,3,23:1,0 0,3,32:1,0 0,6,72:2,0 0,6,95:2,0 0,3,24:1,0 0,6,65:2,0 0,3,37:1,0 15 201 . A G,<*> 0 . DP=80;I16=19,17,21,15,1380,57328,1308,52148,2160,129600,2137,127369,613,12599,514,10028;QS=25,27,0;VDB=0.895839;SGB=-4.94122;RPB=0.999937;MQB=0.979662;MQSB=0.974642;BQB=0.739382;MQ0F=0 PL:AD 0,3,36,3,36,36:1,0,0 0,6,93,6,93,93:2,0,0 0,3,33,3,33,33:1,0,0 0,3,32,3,32,32:1,0,0 0,3,36,3,36,36:1,0,0 0,3,32,3,32,32:1,0,0 0,3,40,3,40,40:1,0,0 0,6,79,6,79,79:2,0,0 0,3,42,3,42,42:1,0,0 0,6,64,6,64,64:2,0,0 0,6,67,6,67,67:2,0,0 0,6,66,6,66,66:2,0,0 0,9,96,9,96,96:3,0,0 0,3,32,3,32,32:1,0,0 0,3,36,3,36,36:1,0,0 0,3,31,3,31,31:1,0,0 0,3,44,3,44,44:1,0,0 0,3,44,3,44,44:1,0,0 0,6,61,6,61,61:2,0,0 0,3,60,3,60,60:1,0,0 0,6,60,6,60,60:2,0,0 0,6,57,6,57,57:2,0,0 0,3,31,3,31,31:1,0,0 0,6,68,6,68,68:2,0,0 0,3,60,3,60,60:1,0,0 39,3,0,39,3,39:0,1,0 31,3,0,31,3,31:0,1,0 37,3,0,37,3,37:0,1,0 60,3,0,60,3,60:0,1,0 38,3,0,38,3,38:0,1,0 36,3,0,36,3,36:0,1,0 37,3,0,37,3,37:0,1,0 85,9,0,85,9,85:0,3,0 39,3,0,39,3,39:0,1,0 31,3,0,31,3,31:0,1,0 63,6,0,63,6,63:0,2,0 29,3,0,29,3,29:0,1,0 32,3,0,32,3,32:0,1,0 43,3,0,43,3,43:0,1,0 27,3,0,27,3,27:0,1,0 43,3,0,43,3,43:0,1,0 34,3,0,34,3,34:0,1,0 46,3,0,46,3,46:0,1,0 144,12,0,144,12,144:0,4,0 59,3,0,59,3,59:0,1,0 16,3,0,16,3,16:0,1,0 37,3,0,37,3,37:0,1,0 57,6,0,57,6,57:0,2,0 91,6,0,91,6,91:0,2,0 21,3,0,21,3,21:0,1,0 52,6,0,52,6,52:0,2,0 26,3,0,26,3,26:0,1,0 15 202 . A <*> 0 . DP=79;I16=39,33,0,0,2736,113310,0,0,4297,256969,0,0,1135,22901,0,0;QS=52,0;MQSB=0.976009;MQ0F=0 PL:AD 0,3,37:1,0 0,6,94:2,0 0,3,34:1,0 0,3,36:1,0 0,3,28:1,0 0,3,30:1,0 0,3,39:1,0 0,6,75:2,0 0,3,41:1,0 0,6,69:2,0 0,6,67:2,0 0,6,66:2,0 0,9,95:3,0 0,3,30:1,0 0,3,36:1,0 0,3,33:1,0 0,3,39:1,0 0,3,44:1,0 0,6,66:2,0 0,3,60:1,0 0,6,58:2,0 0,6,59:2,0 0,3,30:1,0 0,6,68:2,0 0,3,60:1,0 0,3,31:1,0 0,3,33:1,0 0,3,40:1,0 0,3,60:1,0 0,3,30:1,0 0,3,38:1,0 0,3,42:1,0 0,9,91:3,0 0,3,39:1,0 0,3,38:1,0 0,6,80:2,0 0,3,42:1,0 0,3,38:1,0 0,3,37:1,0 0,3,32:1,0 0,3,38:1,0 0,3,40:1,0 0,3,43:1,0 0,12,119:4,0 0,3,60:1,0 0,3,16:1,0 0,3,29:1,0 0,6,66:2,0 0,6,95:2,0 0,3,21:1,0 0,6,59:2,0 0,3,33:1,0 15 203 . C <*> 0 . DP=78;I16=38,34,0,0,3029,137265,0,0,4297,256969,0,0,1143,23227,0,0;QS=52,0;MQSB=0.977296;MQ0F=0 PL:AD 0,3,44:1,0 0,6,95:2,0 0,3,41:1,0 0,3,43:1,0 0,3,39:1,0 0,3,35:1,0 0,3,38:1,0 0,6,83:2,0 0,3,46:1,0 0,6,72:2,0 0,6,76:2,0 0,6,75:2,0 0,9,112:3,0 0,3,39:1,0 0,3,42:1,0 0,3,38:1,0 0,3,44:1,0 0,3,44:1,0 0,6,68:2,0 0,3,40:1,0 0,6,61:2,0 0,6,66:2,0 0,3,37:1,0 0,6,80:2,0 0,3,60:1,0 0,3,40:1,0 0,3,39:1,0 0,3,43:1,0 0,3,60:1,0 0,3,39:1,0 0,3,42:1,0 0,3,43:1,0 0,9,105:3,0 0,3,39:1,0 0,3,37:1,0 0,6,99:2,0 0,3,40:1,0 0,3,39:1,0 0,3,41:1,0 0,3,38:1,0 0,3,38:1,0 0,3,38:1,0 0,3,46:1,0 0,12,143:4,0 0,3,60:1,0 0,3,16:1,0 0,3,37:1,0 0,6,72:2,0 0,6,96:2,0 0,3,21:1,0 0,6,62:2,0 0,3,39:1,0 15 204 . A <*> 0 . DP=77;I16=38,33,0,0,2711,113881,0,0,4237,253369,0,0,1124,22880,0,0;QS=51,0;MQSB=0.976296;MQ0F=0 PL:AD 0,3,37:1,0 0,6,94:2,0 0,3,35:1,0 0,3,37:1,0 0,3,37:1,0 0,3,36:1,0 0,3,38:1,0 0,6,76:2,0 0,3,42:1,0 0,6,75:2,0 0,6,67:2,0 0,6,62:2,0 0,9,93:3,0 0,3,30:1,0 0,3,36:1,0 0,3,31:1,0 0,3,44:1,0 0,3,44:1,0 0,6,61:2,0 0,3,31:1,0 0,6,59:2,0 0,6,58:2,0 0,3,31:1,0 0,6,67:2,0 0,3,60:1,0 0,3,29:1,0 0,3,30:1,0 0,3,39:1,0 0,3,60:1,0 0,3,31:1,0 0,3,39:1,0 0,3,43:1,0 0,9,90:3,0 0,3,38:1,0 0,3,38:1,0 0,6,92:2,0 0,3,29:1,0 0,3,39:1,0 0,3,37:1,0 0,3,32:1,0 0,3,38:1,0 0,3,38:1,0 0,3,44:1,0 0,12,120:4,0 0,3,60:1,0 0,0,0:0,0 0,3,29:1,0 0,6,65:2,0 0,6,96:2,0 0,3,21:1,0 0,6,52:2,0 0,3,32:1,0 15 205 . T <*> 0 . DP=76;I16=38,32,0,0,2493,97025,0,0,4177,249769,0,0,1105,22583,0,0;QS=50,0;MQSB=0.975224;MQ0F=0 PL:AD 0,3,34:1,0 0,6,90:2,0 0,3,28:1,0 0,3,31:1,0 0,3,37:1,0 0,3,19:1,0 0,3,36:1,0 0,6,75:2,0 0,3,41:1,0 0,6,74:2,0 0,6,63:2,0 0,6,57:2,0 0,9,92:3,0 0,3,30:1,0 0,3,34:1,0 0,3,30:1,0 0,3,42:1,0 0,3,43:1,0 0,6,58:2,0 0,3,31:1,0 0,6,56:2,0 0,6,56:2,0 0,3,31:1,0 0,6,64:2,0 0,3,60:1,0 0,3,34:1,0 0,3,32:1,0 0,3,37:1,0 0,3,60:1,0 0,3,29:1,0 0,3,37:1,0 0,3,42:1,0 0,9,87:3,0 0,3,20:1,0 0,3,25:1,0 0,6,90:2,0 0,3,18:1,0 0,3,35:1,0 0,3,32:1,0 0,3,32:1,0 0,3,40:1,0 0,3,40:1,0 0,3,37:1,0 0,12,114:4,0 0,3,35:1,0 0,0,0:0,0 0,3,36:1,0 0,6,63:2,0 0,6,93:2,0 0,0,0:0,0 0,6,51:2,0 0,3,32:1,0 15 206 . A <*> 0 . DP=69;I16=35,29,0,0,2387,96411,0,0,3817,228169,0,0,1115,22903,0,0;QS=47,0;MQSB=0.972533;MQ0F=0 PL:AD 0,3,36:1,0 0,6,85:2,0 0,3,32:1,0 0,3,34:1,0 0,3,32:1,0 0,0,0:0,0 0,3,34:1,0 0,6,79:2,0 0,3,42:1,0 0,6,79:2,0 0,6,65:2,0 0,3,33:1,0 0,9,93:3,0 0,3,32:1,0 0,3,33:1,0 0,3,30:1,0 0,3,42:1,0 0,3,42:1,0 0,6,59:2,0 0,3,33:1,0 0,3,28:1,0 0,6,56:2,0 0,3,33:1,0 0,6,66:2,0 0,3,60:1,0 0,0,0:0,0 0,3,29:1,0 0,3,36:1,0 0,3,60:1,0 0,3,33:1,0 0,3,34:1,0 0,3,38:1,0 0,9,88:3,0 0,0,0:0,0 0,3,36:1,0 0,6,93:2,0 0,3,25:1,0 0,3,38:1,0 0,3,37:1,0 0,3,30:1,0 0,3,41:1,0 0,3,37:1,0 0,3,44:1,0 0,12,121:4,0 0,3,35:1,0 0,0,0:0,0 0,3,31:1,0 0,6,62:2,0 0,6,92:2,0 0,0,0:0,0 0,3,32:1,0 0,3,31:1,0 15 207 . A <*> 0 . DP=69;I16=34,28,0,0,2438,102832,0,0,3697,220969,0,0,1067,21911,0,0;QS=46,0;MQSB=0.971502;MQ0F=0 PL:AD 0,3,34:1,0 0,6,92:2,0 0,3,27:1,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,3,36:1,0 0,6,79:2,0 0,3,42:1,0 0,6,75:2,0 0,3,34:1,0 0,3,37:1,0 0,9,98:3,0 0,3,33:1,0 0,3,35:1,0 0,3,33:1,0 0,3,44:1,0 0,3,44:1,0 0,6,66:2,0 0,3,33:1,0 0,3,33:1,0 0,6,61:2,0 0,3,33:1,0 0,6,70:2,0 0,3,60:1,0 0,0,0:0,0 0,3,36:1,0 0,3,33:1,0 0,3,60:1,0 0,3,33:1,0 0,3,40:1,0 0,3,43:1,0 0,9,95:3,0 0,0,0:0,0 0,3,38:1,0 0,6,93:2,0 0,0,0:0,0 0,3,40:1,0 0,3,35:1,0 0,3,33:1,0 0,3,41:1,0 0,3,41:1,0 0,3,44:1,0 0,12,125:4,0 0,3,34:1,0 0,0,0:0,0 0,3,31:1,0 0,6,70:2,0 0,6,94:2,0 0,0,0:0,0 0,3,37:1,0 0,3,33:1,0 15 208 . A <*> 0 . DP=68;I16=34,29,0,0,2374,97444,0,0,3757,224569,0,0,1075,22219,0,0;QS=47,0;MQSB=0.972896;MQ0F=0 PL:AD 0,3,36:1,0 0,6,93:2,0 0,3,30:1,0 0,3,37:1,0 0,3,39:1,0 0,0,0:0,0 0,3,35:1,0 0,6,78:2,0 0,3,36:1,0 0,6,70:2,0 0,3,33:1,0 0,3,36:1,0 0,9,93:3,0 0,3,29:1,0 0,3,34:1,0 0,3,33:1,0 0,3,43:1,0 0,3,40:1,0 0,6,67:2,0 0,3,29:1,0 0,3,31:1,0 0,6,57:2,0 0,3,30:1,0 0,6,70:2,0 0,3,60:1,0 0,0,0:0,0 0,3,36:1,0 0,3,19:1,0 0,3,60:1,0 0,3,30:1,0 0,3,38:1,0 0,3,43:1,0 0,9,92:3,0 0,0,0:0,0 0,3,38:1,0 0,6,90:2,0 0,3,20:1,0 0,3,40:1,0 0,3,37:1,0 0,3,33:1,0 0,3,40:1,0 0,3,33:1,0 0,3,43:1,0 0,12,117:4,0 0,3,35:1,0 0,0,0:0,0 0,3,27:1,0 0,6,69:2,0 0,6,94:2,0 0,0,0:0,0 0,3,37:1,0 0,3,31:1,0 15 209 . C <*> 0 . DP=66;I16=33,28,0,0,2558,116134,0,0,3637,217369,0,0,1060,21986,0,0;QS=45,0;MQSB=0.971889;MQ0F=0 PL:AD 0,3,43:1,0 0,6,92:2,0 0,3,34:1,0 0,3,38:1,0 0,3,41:1,0 0,0,0:0,0 0,3,33:1,0 0,6,81:2,0 0,3,45:1,0 0,6,79:2,0 0,3,41:1,0 0,3,39:1,0 0,9,109:3,0 0,3,40:1,0 0,3,43:1,0 0,3,38:1,0 0,3,35:1,0 0,3,45:1,0 0,6,70:2,0 0,3,38:1,0 0,0,0:0,0 0,6,62:2,0 0,3,36:1,0 0,6,80:2,0 0,3,60:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,60:1,0 0,3,37:1,0 0,3,40:1,0 0,3,43:1,0 0,9,99:3,0 0,0,0:0,0 0,3,37:1,0 0,6,97:2,0 0,3,14:1,0 0,3,40:1,0 0,3,43:1,0 0,3,38:1,0 0,3,39:1,0 0,3,36:1,0 0,3,46:1,0 0,12,140:4,0 0,3,37:1,0 0,0,0:0,0 0,3,36:1,0 0,6,72:2,0 0,6,95:2,0 0,0,0:0,0 0,3,39:1,0 0,3,36:1,0 15 210 . C <*> 0 . DP=65;I16=32,28,0,0,2550,116972,0,0,3577,213769,0,0,1046,21834,0,0;QS=45,0;MQSB=0.972288;MQ0F=0 PL:AD 0,3,42:1,0 0,6,99:2,0 0,3,38:1,0 0,3,43:1,0 0,3,38:1,0 0,0,0:0,0 0,3,28:1,0 0,6,83:2,0 0,3,45:1,0 0,6,79:2,0 0,3,42:1,0 0,3,39:1,0 0,9,112:3,0 0,3,41:1,0 0,3,43:1,0 0,3,33:1,0 0,3,36:1,0 0,3,40:1,0 0,6,70:2,0 0,3,40:1,0 0,0,0:0,0 0,3,33:1,0 0,3,38:1,0 0,6,82:2,0 0,3,60:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,3,60:1,0 0,3,39:1,0 0,3,42:1,0 0,3,44:1,0 0,9,100:3,0 0,0,0:0,0 0,3,38:1,0 0,6,98:2,0 0,3,19:1,0 0,3,41:1,0 0,3,42:1,0 0,3,33:1,0 0,3,43:1,0 0,3,40:1,0 0,3,46:1,0 0,12,141:4,0 0,3,42:1,0 0,0,0:0,0 0,3,30:1,0 0,6,76:2,0 0,6,96:2,0 0,0,0:0,0 0,3,39:1,0 0,3,33:1,0 15 211 . A <*> 0 . DP=63;I16=31,26,0,0,2243,95567,0,0,3420,205200,0,0,1009,21135,0,0;QS=42,0;MQSB=1;MQ0F=0 PL:AD 0,3,35:1,0 0,6,91:2,0 0,3,34:1,0 0,3,32:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,78:2,0 0,3,40:1,0 0,6,79:2,0 0,3,34:1,0 0,3,33:1,0 0,9,92:3,0 0,3,33:1,0 0,3,36:1,0 0,3,32:1,0 0,3,44:1,0 0,3,44:1,0 0,6,59:2,0 0,3,33:1,0 0,0,0:0,0 0,3,32:1,0 0,3,32:1,0 0,6,67:2,0 0,3,60:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,60:1,0 0,3,33:1,0 0,3,39:1,0 0,3,43:1,0 0,9,91:3,0 0,0,0:0,0 0,3,37:1,0 0,6,94:2,0 0,0,0:0,0 0,3,40:1,0 0,3,37:1,0 0,3,31:1,0 0,3,41:1,0 0,3,41:1,0 0,3,44:1,0 0,12,125:4,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,6,66:2,0 0,6,96:2,0 0,0,0:0,0 0,3,35:1,0 0,3,29:1,0 15 212 . A <*> 0 . DP=62;I16=30,27,0,0,2325,101879,0,0,3420,205200,0,0,1018,21512,0,0;QS=42,0;MQSB=1;MQ0F=0 PL:AD 0,3,39:1,0 0,6,91:2,0 0,3,36:1,0 0,3,39:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,6,85:2,0 0,3,42:1,0 0,6,79:2,0 0,3,38:1,0 0,3,37:1,0 0,9,103:3,0 0,3,36:1,0 0,3,40:1,0 0,3,33:1,0 0,3,40:1,0 0,3,44:1,0 0,6,64:2,0 0,3,36:1,0 0,0,0:0,0 0,3,29:1,0 0,3,35:1,0 0,6,74:2,0 0,3,60:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,60:1,0 0,3,35:1,0 0,3,39:1,0 0,3,41:1,0 0,9,97:3,0 0,0,0:0,0 0,3,38:1,0 0,6,96:2,0 0,3,29:1,0 0,3,40:1,0 0,3,40:1,0 0,3,33:1,0 0,3,39:1,0 0,3,36:1,0 0,3,46:1,0 0,12,131:4,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,6,67:2,0 0,6,91:2,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 15 213 . G <*> 0 . DP=61;I16=29,28,0,0,2385,106019,0,0,3420,205200,0,0,1013,21383,0,0;QS=42,0;MQSB=1;MQ0F=0 PL:AD 0,3,42:1,0 0,6,91:2,0 0,3,38:1,0 0,3,38:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,6,83:2,0 0,3,36:1,0 0,6,80:2,0 0,3,40:1,0 0,3,39:1,0 0,9,108:3,0 0,3,38:1,0 0,3,42:1,0 0,3,40:1,0 0,3,45:1,0 0,3,45:1,0 0,6,75:2,0 0,3,34:1,0 0,0,0:0,0 0,3,39:1,0 0,3,32:1,0 0,6,82:2,0 0,3,40:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,3,60:1,0 0,3,33:1,0 0,3,38:1,0 0,3,41:1,0 0,9,106:3,0 0,0,0:0,0 0,3,37:1,0 0,6,94:2,0 0,3,29:1,0 0,3,41:1,0 0,3,41:1,0 0,3,29:1,0 0,3,38:1,0 0,3,40:1,0 0,3,45:1,0 0,12,136:4,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,6,76:2,0 0,6,94:2,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 15 214 . G <*> 0 . DP=60;I16=28,28,0,0,2336,103072,0,0,3360,201600,0,0,995,21109,0,0;QS=41,0;MQSB=1;MQ0F=0 PL:AD 0,3,39:1,0 0,6,95:2,0 0,3,37:1,0 0,3,43:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,83:2,0 0,3,21:1,0 0,6,78:2,0 0,3,39:1,0 0,3,40:1,0 0,9,108:3,0 0,3,38:1,0 0,3,31:1,0 0,3,37:1,0 0,3,40:1,0 0,3,42:1,0 0,6,74:2,0 0,3,38:1,0 0,0,0:0,0 0,3,37:1,0 0,3,38:1,0 0,6,81:2,0 0,3,40:1,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,60:1,0 0,3,37:1,0 0,3,38:1,0 0,3,45:1,0 0,9,107:3,0 0,0,0:0,0 0,3,39:1,0 0,6,96:2,0 0,3,35:1,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,3,37:1,0 0,3,42:1,0 0,3,46:1,0 0,12,138:4,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,6,73:2,0 0,6,97:2,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 15 215 . A <*> 0 . DP=59;I16=28,26,0,0,2040,82942,0,0,3240,194400,0,0,953,20281,0,0;QS=39,0;MQSB=1;MQ0F=0 PL:AD 0,3,35:1,0 0,6,91:2,0 0,3,25:1,0 0,3,35:1,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,6,79:2,0 0,0,0:0,0 0,6,72:2,0 0,3,34:1,0 0,3,33:1,0 0,9,88:3,0 0,3,32:1,0 0,3,34:1,0 0,3,32:1,0 0,3,43:1,0 0,3,40:1,0 0,6,61:2,0 0,3,31:1,0 0,0,0:0,0 0,3,33:1,0 0,3,32:1,0 0,6,68:2,0 0,3,36:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,3,36:1,0 0,3,42:1,0 0,9,94:3,0 0,0,0:0,0 0,3,38:1,0 0,6,92:2,0 0,0,0:0,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,3,37:1,0 0,3,41:1,0 0,3,44:1,0 0,12,119:4,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,6,65:2,0 0,6,90:2,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 216 . A <*> 0 . DP=58;I16=28,26,0,0,2092,86850,0,0,3240,194400,0,0,960,20670,0,0;QS=40,0;MQSB=1;MQ0F=0 PL:AD 0,3,37:1,0 0,6,91:2,0 0,3,34:1,0 0,3,37:1,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,6,75:2,0 0,0,0:0,0 0,6,75:2,0 0,3,33:1,0 0,3,36:1,0 0,6,69:2,0 0,3,31:1,0 0,3,38:1,0 0,3,33:1,0 0,3,43:1,0 0,3,44:1,0 0,6,65:2,0 0,3,31:1,0 0,0,0:0,0 0,3,31:1,0 0,3,32:1,0 0,6,69:2,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,60:1,0 0,3,31:1,0 0,3,39:1,0 0,3,43:1,0 0,9,94:3,0 0,0,0:0,0 0,3,38:1,0 0,6,92:2,0 0,3,27:1,0 0,3,41:1,0 0,3,37:1,0 0,0,0:0,0 0,3,36:1,0 0,3,41:1,0 0,3,44:1,0 0,12,117:4,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,6,68:2,0 0,6,96:2,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 15 217 . T <*> 0 . DP=58;I16=28,26,0,0,1980,77978,0,0,3240,194400,0,0,940,20396,0,0;QS=40,0;MQSB=1;MQ0F=0 PL:AD 0,3,33:1,0 0,6,90:2,0 0,3,30:1,0 0,3,33:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,6,73:2,0 0,0,0:0,0 0,6,66:2,0 0,3,32:1,0 0,3,33:1,0 0,6,66:2,0 0,3,30:1,0 0,3,35:1,0 0,3,31:1,0 0,3,39:1,0 0,3,44:1,0 0,6,60:2,0 0,3,30:1,0 0,0,0:0,0 0,3,30:1,0 0,3,31:1,0 0,6,61:2,0 0,3,35:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,60:1,0 0,3,30:1,0 0,3,37:1,0 0,3,39:1,0 0,9,90:3,0 0,0,0:0,0 0,3,35:1,0 0,6,91:2,0 0,3,20:1,0 0,3,40:1,0 0,3,35:1,0 0,0,0:0,0 0,3,35:1,0 0,3,41:1,0 0,3,43:1,0 0,12,114:4,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,6,64:2,0 0,6,95:2,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 15 218 . A <*> 0 . DP=58;I16=28,26,0,0,2000,79614,0,0,3240,194400,0,0,920,20182,0,0;QS=40,0;MQSB=1;MQ0F=0 PL:AD 0,3,35:1,0 0,6,93:2,0 0,3,29:1,0 0,3,35:1,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,6,78:2,0 0,0,0:0,0 0,6,74:2,0 0,3,34:1,0 0,3,32:1,0 0,6,64:2,0 0,3,33:1,0 0,3,37:1,0 0,3,30:1,0 0,3,42:1,0 0,3,43:1,0 0,6,59:2,0 0,3,33:1,0 0,0,0:0,0 0,3,27:1,0 0,3,32:1,0 0,6,65:2,0 0,3,35:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,60:1,0 0,3,32:1,0 0,3,35:1,0 0,3,42:1,0 0,9,88:3,0 0,0,0:0,0 0,3,34:1,0 0,6,94:2,0 0,3,23:1,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,3,36:1,0 0,3,40:1,0 0,3,41:1,0 0,12,109:4,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,6,61:2,0 0,6,93:2,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 15 219 . A <*> 0 . DP=56;I16=27,25,0,0,1958,77738,0,0,3120,187200,0,0,901,19975,0,0;QS=39,0;MQSB=1;MQ0F=0 PL:AD 0,3,36:1,0 0,6,91:2,0 0,3,30:1,0 0,3,35:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,78:2,0 0,0,0:0,0 0,6,61:2,0 0,3,32:1,0 0,3,38:1,0 0,6,69:2,0 0,3,30:1,0 0,3,38:1,0 0,3,33:1,0 0,3,40:1,0 0,3,41:1,0 0,6,66:2,0 0,3,31:1,0 0,0,0:0,0 0,3,33:1,0 0,3,31:1,0 0,6,68:2,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,40:1,0 0,3,31:1,0 0,3,38:1,0 0,3,43:1,0 0,9,95:3,0 0,0,0:0,0 0,3,37:1,0 0,6,92:2,0 0,0,0:0,0 0,3,41:1,0 0,3,36:1,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,3,41:1,0 0,9,94:3,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,67:2,0 0,6,94:2,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 15 220 . T <*> 0 . DP=55;I16=27,24,0,0,1875,72777,0,0,3060,183600,0,0,907,20445,0,0;QS=39,0;MQSB=1;MQ0F=0 PL:AD 0,3,32:1,0 0,6,93:2,0 0,0,0:0,0 0,3,37:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,6,72:2,0 0,0,0:0,0 0,3,38:1,0 0,3,34:1,0 0,3,33:1,0 0,6,67:2,0 0,3,29:1,0 0,3,29:1,0 0,3,31:1,0 0,3,39:1,0 0,3,41:1,0 0,6,60:2,0 0,3,32:1,0 0,0,0:0,0 0,3,29:1,0 0,3,32:1,0 0,6,66:2,0 0,3,36:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,41:1,0 0,3,31:1,0 0,3,37:1,0 0,3,37:1,0 0,9,91:3,0 0,0,0:0,0 0,3,32:1,0 0,6,93:2,0 0,3,35:1,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,3,35:1,0 0,3,41:1,0 0,3,36:1,0 0,9,97:3,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,60:2,0 0,6,93:2,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 221 . C <*> 0 . DP=54;I16=26,26,0,0,2092,88232,0,0,3120,187200,0,0,913,20817,0,0;QS=40,0;MQSB=1;MQ0F=0 PL:AD 0,3,46:1,0 0,6,87:2,0 0,3,16:1,0 0,3,43:1,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,6,85:2,0 0,0,0:0,0 0,3,46:1,0 0,3,42:1,0 0,3,40:1,0 0,6,73:2,0 0,3,33:1,0 0,3,43:1,0 0,3,38:1,0 0,3,39:1,0 0,3,40:1,0 0,6,69:2,0 0,3,40:1,0 0,0,0:0,0 0,3,36:1,0 0,3,37:1,0 0,6,80:2,0 0,3,38:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,40:1,0 0,3,38:1,0 0,3,37:1,0 0,3,44:1,0 0,9,108:3,0 0,0,0:0,0 0,3,37:1,0 0,6,99:2,0 0,3,41:1,0 0,3,42:1,0 0,3,44:1,0 0,0,0:0,0 0,3,42:1,0 0,3,41:1,0 0,3,20:1,0 0,9,113:3,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,6,71:2,0 0,6,87:2,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 15 222 . A <*> 0 . DP=51;I16=26,23,0,0,1775,67619,0,0,2940,176400,0,0,894,20508,0,0;QS=37,0;MQSB=1;MQ0F=0 PL:AD 0,3,22:1,0 0,6,77:2,0 0,0,0:0,0 0,3,37:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,6,74:2,0 0,0,0:0,0 0,3,36:1,0 0,3,34:1,0 0,3,35:1,0 0,6,63:2,0 0,0,0:0,0 0,3,36:1,0 0,3,32:1,0 0,3,44:1,0 0,3,41:1,0 0,6,64:2,0 0,3,33:1,0 0,0,0:0,0 0,3,32:1,0 0,3,31:1,0 0,6,63:2,0 0,3,34:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,39:1,0 0,3,32:1,0 0,3,41:1,0 0,3,44:1,0 0,9,93:3,0 0,0,0:0,0 0,3,39:1,0 0,6,94:2,0 0,3,32:1,0 0,3,41:1,0 0,3,19:1,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,0,0:0,0 0,9,100:3,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,6,64:2,0 0,6,81:2,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 223 . A <*> 0 . DP=48;I16=26,20,0,0,1676,64284,0,0,2760,165600,0,0,874,20040,0,0;QS=35,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,86:2,0 0,0,0:0,0 0,3,37:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,6,77:2,0 0,0,0:0,0 0,3,34:1,0 0,3,33:1,0 0,3,36:1,0 0,3,35:1,0 0,0,0:0,0 0,3,16:1,0 0,3,32:1,0 0,3,41:1,0 0,3,44:1,0 0,6,67:2,0 0,3,31:1,0 0,0,0:0,0 0,3,31:1,0 0,3,31:1,0 0,6,68:2,0 0,3,34:1,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,40:1,0 0,3,30:1,0 0,3,38:1,0 0,3,44:1,0 0,9,95:3,0 0,0,0:0,0 0,3,38:1,0 0,6,92:2,0 0,3,34:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,42:1,0 0,0,0:0,0 0,9,79:3,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,62:2,0 0,6,76:2,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 224 . T <*> 0 . DP=47;I16=26,19,0,0,1653,63239,0,0,2700,162000,0,0,854,19562,0,0;QS=34,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,92:2,0 0,0,0:0,0 0,3,38:1,0 0,3,25:1,0 0,0,0:0,0 0,0,0:0,0 0,6,79:2,0 0,0,0:0,0 0,3,44:1,0 0,3,33:1,0 0,3,33:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,43:1,0 0,3,43:1,0 0,6,60:2,0 0,3,32:1,0 0,0,0:0,0 0,3,30:1,0 0,3,31:1,0 0,6,65:2,0 0,3,39:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,40:1,0 0,3,31:1,0 0,3,35:1,0 0,3,39:1,0 0,9,90:3,0 0,0,0:0,0 0,3,37:1,0 0,6,92:2,0 0,3,38:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,41:1,0 0,0,0:0,0 0,9,98:3,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,6,56:2,0 0,6,76:2,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 15 225 . G <*> 0 . DP=47;I16=26,19,0,0,1868,80948,0,0,2700,162000,0,0,832,19026,0,0;QS=34,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,100:2,0 0,0,0:0,0 0,3,43:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,6,82:2,0 0,0,0:0,0 0,3,39:1,0 0,3,40:1,0 0,3,41:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,42:1,0 0,3,47:1,0 0,6,74:2,0 0,3,38:1,0 0,0,0:0,0 0,3,35:1,0 0,3,36:1,0 0,6,81:2,0 0,3,22:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,45:1,0 0,3,36:1,0 0,3,44:1,0 0,3,44:1,0 0,9,109:3,0 0,0,0:0,0 0,3,39:1,0 0,6,97:2,0 0,3,40:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,40:1,0 0,0,0:0,0 0,9,114:3,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,6,71:2,0 0,6,80:2,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 15 226 . C <*> 0 . DP=46;I16=26,17,0,0,1700,70620,0,0,2580,154800,0,0,786,17908,0,0;QS=32,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,88:2,0 0,0,0:0,0 0,3,44:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,6,69:2,0 0,0,0:0,0 0,3,35:1,0 0,3,41:1,0 0,3,40:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,40:1,0 0,3,46:1,0 0,6,71:2,0 0,3,36:1,0 0,0,0:0,0 0,3,23:1,0 0,3,35:1,0 0,6,77:2,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,3,40:1,0 0,3,36:1,0 0,3,44:1,0 0,3,32:1,0 0,9,106:3,0 0,0,0:0,0 0,3,37:1,0 0,6,94:2,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,9,109:3,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,6,62:2,0 0,6,86:2,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 15 227 . C <*> 0 . DP=44;I16=24,19,0,0,1729,71915,0,0,2580,154800,0,0,816,18656,0,0;QS=33,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,96:2,0 0,0,0:0,0 0,3,42:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,6,84:2,0 0,0,0:0,0 0,3,42:1,0 0,3,41:1,0 0,3,39:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,45:1,0 0,3,46:1,0 0,6,73:2,0 0,3,40:1,0 0,0,0:0,0 0,3,32:1,0 0,3,37:1,0 0,6,81:2,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,44:1,0 0,3,37:1,0 0,3,43:1,0 0,3,43:1,0 0,9,100:3,0 0,0,0:0,0 0,3,39:1,0 0,6,70:2,0 0,3,20:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,9,110:3,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,6,82:2,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 15 228 . A <*> 0 . DP=43;I16=23,19,0,0,1474,52654,0,0,2520,151200,0,0,797,18193,0,0;QS=32,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,80:2,0 0,0,0:0,0 0,3,37:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,6,75:2,0 0,0,0:0,0 0,3,43:1,0 0,3,33:1,0 0,3,34:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,44:1,0 0,3,37:1,0 0,6,63:2,0 0,3,31:1,0 0,0,0:0,0 0,3,29:1,0 0,3,29:1,0 0,6,65:2,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,35:1,0 0,3,29:1,0 0,3,37:1,0 0,3,41:1,0 0,9,90:3,0 0,0,0:0,0 0,3,39:1,0 0,6,57:2,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,20:1,0 0,3,42:1,0 0,0,0:0,0 0,9,92:3,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,77:2,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 229 . T <*> 0 . DP=41;I16=22,19,0,0,1389,47693,0,0,2460,147600,0,0,804,18342,0,0;QS=31,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,74:2,0 0,0,0:0,0 0,3,31:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,6,64:2,0 0,0,0:0,0 0,3,39:1,0 0,3,33:1,0 0,3,33:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,40:1,0 0,3,43:1,0 0,6,57:2,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,6,64:2,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,42:1,0 0,3,27:1,0 0,3,30:1,0 0,3,39:1,0 0,9,87:3,0 0,0,0:0,0 0,3,33:1,0 0,6,56:2,0 0,3,32:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,9,92:3,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,6,74:2,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 230 . A <*> 0 . DP=41;I16=22,19,0,0,1418,50194,0,0,2460,147600,0,0,784,17804,0,0;QS=31,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,77:2,0 0,0,0:0,0 0,3,38:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,6,79:2,0 0,0,0:0,0 0,3,37:1,0 0,3,38:1,0 0,3,33:1,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,39:1,0 0,3,35:1,0 0,6,59:2,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,69:2,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,3,42:1,0 0,3,29:1,0 0,3,28:1,0 0,3,36:1,0 0,9,90:3,0 0,0,0:0,0 0,3,36:1,0 0,6,66:2,0 0,3,20:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,9,84:3,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,74:2,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 15 231 . G <*> 0 . DP=40;I16=22,17,0,0,1533,61007,0,0,2340,140400,0,0,740,16680,0,0;QS=29,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,86:2,0 0,0,0:0,0 0,3,43:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,6,61:2,0 0,0,0:0,0 0,3,43:1,0 0,3,38:1,0 0,3,40:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,45:1,0 0,3,42:1,0 0,6,75:2,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,6,79:2,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,30:1,0 0,3,40:1,0 0,9,106:3,0 0,0,0:0,0 0,3,39:1,0 0,6,69:2,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,9,105:3,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,6,78:2,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 15 232 . T <*> 0 . DP=38;I16=21,17,0,0,1336,47618,0,0,2280,136800,0,0,748,16842,0,0;QS=30,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,76:2,0 0,0,0:0,0 0,3,40:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,44:1,0 0,3,37:1,0 0,3,32:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,39:1,0 0,3,36:1,0 0,6,59:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,69:2,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,32:1,0 0,3,36:1,0 0,6,64:2,0 0,0,0:0,0 0,3,36:1,0 0,6,62:2,0 0,3,24:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,9,93:3,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,6,75:2,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 233 . T <*> 0 . DP=37;I16=21,16,0,0,1320,47930,0,0,2220,133200,0,0,732,16412,0,0;QS=30,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,84:2,0 0,0,0:0,0 0,3,40:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,3,44:1,0 0,3,36:1,0 0,3,35:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,40:1,0 0,3,39:1,0 0,6,58:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,6,70:2,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,33:1,0 0,3,33:1,0 0,6,65:2,0 0,0,0:0,0 0,3,38:1,0 0,6,62:2,0 0,3,16:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,6,71:2,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,72:2,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 234 . T <*> 0 . DP=37;I16=21,16,0,0,1316,47626,0,0,2220,133200,0,0,714,15916,0,0;QS=30,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,83:2,0 0,0,0:0,0 0,3,39:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,44:1,0 0,3,36:1,0 0,3,34:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,43:1,0 0,3,39:1,0 0,6,62:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,69:2,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,29:1,0 0,3,32:1,0 0,6,65:2,0 0,0,0:0,0 0,3,34:1,0 0,6,62:2,0 0,3,19:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,6,71:2,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,71:2,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 235 . T <*> 0 . DP=37;I16=21,16,0,0,1325,48123,0,0,2220,133200,0,0,696,15456,0,0;QS=30,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,83:2,0 0,0,0:0,0 0,3,40:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,44:1,0 0,3,36:1,0 0,3,34:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,43:1,0 0,3,41:1,0 0,6,63:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,69:2,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,28:1,0 0,3,30:1,0 0,6,64:2,0 0,0,0:0,0 0,3,34:1,0 0,6,62:2,0 0,3,28:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,6,72:2,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,69:2,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 236 . T <*> 0 . DP=37;I16=21,16,0,0,1265,44087,0,0,2220,133200,0,0,678,15032,0,0;QS=30,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,73:2,0 0,0,0:0,0 0,3,33:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,3,31:1,0 0,3,34:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,43:1,0 0,3,41:1,0 0,6,61:2,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,67:2,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,28:1,0 0,3,29:1,0 0,6,63:2,0 0,0,0:0,0 0,3,37:1,0 0,6,56:2,0 0,3,20:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,6,68:2,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,63:2,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 237 . A <*> 0 . DP=34;I16=19,15,0,0,1149,39531,0,0,2040,122400,0,0,662,14592,0,0;QS=29,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,72:2,0 0,0,0:0,0 0,3,35:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,43:1,0 0,3,33:1,0 0,3,32:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,39:1,0 0,3,39:1,0 0,6,55:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,6,65:2,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,23:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,33:1,0 0,6,61:2,0 0,3,23:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,6,62:2,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 15 238 . A <*> 0 . DP=33;I16=18,14,0,0,1155,42133,0,0,1920,115200,0,0,621,13509,0,0;QS=27,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,64:2,0 0,0,0:0,0 0,3,38:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,42:1,0 0,3,31:1,0 0,3,37:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,44:1,0 0,3,39:1,0 0,6,67:2,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,6,70:2,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,3,38:1,0 0,6,58:2,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,6,70:2,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,37:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 239 . T <*> 0 . DP=33;I16=18,15,0,0,1101,37427,0,0,1980,118800,0,0,628,13610,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,65:2,0 0,0,0:0,0 0,3,34:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,37:1,0 0,3,31:1,0 0,3,33:1,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,43:1,0 0,3,44:1,0 0,6,58:2,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,6,62:2,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,33:1,0 0,6,56:2,0 0,3,20:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,6,67:2,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,32:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 240 . A <*> 0 . DP=33;I16=18,15,0,0,1175,42401,0,0,1980,118800,0,0,609,13073,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,75:2,0 0,0,0:0,0 0,3,38:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,46:1,0 0,0,0:0,0 0,3,36:1,0 0,3,36:1,0 0,3,31:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,42:1,0 0,3,38:1,0 0,6,58:2,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,6,66:2,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,35:1,0 0,6,66:2,0 0,3,27:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,6,70:2,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 15 241 . G <*> 0 . DP=33;I16=18,15,0,0,1297,51275,0,0,1980,118800,0,0,589,12525,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,72:2,0 0,0,0:0,0 0,3,42:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,43:1,0 0,3,38:1,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,40:1,0 0,3,43:1,0 0,6,72:2,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,79:2,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,38:1,0 0,6,69:2,0 0,3,41:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,6,73:2,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 242 . T <*> 0 . DP=33;I16=18,15,0,0,1128,39144,0,0,1980,118800,0,0,569,12017,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,79:2,0 0,0,0:0,0 0,3,38:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,39:1,0 0,3,32:1,0 0,3,30:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,39:1,0 0,3,39:1,0 0,6,57:2,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,6,63:2,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,34:1,0 0,6,59:2,0 0,3,21:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,6,67:2,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,37:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 15 243 . G <*> 0 . DP=33;I16=18,15,0,0,1262,48946,0,0,1980,118800,0,0,549,11549,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,80:2,0 0,0,0:0,0 0,3,42:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,46:1,0 0,0,0:0,0 0,3,44:1,0 0,3,39:1,0 0,3,37:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,39:1,0 0,3,43:1,0 0,6,73:2,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,6,79:2,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,38:1,0 0,6,69:2,0 0,3,25:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,25:1,0 0,0,0:0,0 0,6,71:2,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 15 244 . C <*> 0 . DP=33;I16=18,15,0,0,1255,48831,0,0,1980,118800,0,0,529,11121,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,80:2,0 0,0,0:0,0 0,3,43:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,47:1,0 0,0,0:0,0 0,3,41:1,0 0,3,39:1,0 0,3,35:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,43:1,0 0,3,42:1,0 0,6,69:2,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,6,77:2,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,37:1,0 0,6,71:2,0 0,3,21:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,16:1,0 0,0,0:0,0 0,6,74:2,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,40:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 15 245 . A <*> 0 . DP=33;I16=18,15,0,0,1125,39009,0,0,1980,118800,0,0,509,10733,0,0;QS=28,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,73:2,0 0,0,0:0,0 0,3,36:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,43:1,0 0,3,30:1,0 0,3,29:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,40:1,0 0,3,40:1,0 0,6,62:2,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,6,63:2,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,38:1,0 0,6,62:2,0 0,3,22:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,23:1,0 0,0,0:0,0 0,6,66:2,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,36:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 15 246 . A <*> 0 . DP=32;I16=17,14,0,0,1078,38064,0,0,1860,111600,0,0,465,9759,0,0;QS=27,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,66:2,0 0,0,0:0,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,3,32:1,0 0,3,31:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,38:1,0 0,3,40:1,0 0,6,63:2,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,38:1,0 0,6,56:2,0 0,3,31:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,6,57:2,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,36:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 15 247 . C <*> 0 . DP=31;I16=18,13,0,0,1139,43013,0,0,1860,111600,0,0,471,10023,0,0;QS=27,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,6,74:2,0 0,0,0:0,0 0,3,41:1,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,46:1,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,3,33:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,40:1,0 0,3,37:1,0 0,6,62:2,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,36:1,0 0,6,73:2,0 0,3,20:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,21:1,0 0,0,0:0,0 0,6,73:2,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,3,41:1,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 15 248 . T <*> 0 . DP=28;I16=15,13,0,0,976,35010,0,0,1680,100800,0,0,454,9648,0,0;QS=25,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,31:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,3,40:1,0 0,3,41:1,0 0,6,67:2,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,38:1,0 0,6,56:2,0 0,3,18:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,6,66:2,0 0,3,20:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,34:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 15 249 . A <*> 0 . DP=27;I16=15,12,0,0,902,31414,0,0,1620,97200,0,0,438,9306,0,0;QS=24,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,39:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,46:1,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,35:1,0 0,3,39:1,0 0,6,51:2,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,35:1,0 0,6,66:2,0 0,3,17:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,24:1,0 0,0,0:0,0 0,6,47:2,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,38:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 15 250 . G <*> 0 . DP=25;I16=14,11,0,0,949,36541,0,0,1500,90000,0,0,424,8994,0,0;QS=24,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,40:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,38:1,0 0,3,37:1,0 0,3,42:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,39:1,0 0,6,69:2,0 0,3,27:1,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,40:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 15 251 . A <*> 0 . DP=25;I16=14,11,0,0,831,28181,0,0,1500,90000,0,0,409,8661,0,0;QS=24,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,34:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,29:1,0 0,3,36:1,0 0,3,33:1,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,39:1,0 0,6,61:2,0 0,3,25:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,17:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,35:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 15 252 . A <*> 0 . DP=24;I16=13,11,0,0,840,29842,0,0,1440,86400,0,0,395,8357,0,0;QS=23,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,35:1,0 0,3,35:1,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,38:1,0 0,6,60:2,0 0,3,31:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,24:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,3,35:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 15 253 . A <*> 0 . DP=24;I16=13,11,0,0,830,29406,0,0,1440,86400,0,0,381,8081,0,0;QS=23,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,18:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,35:1,0 0,3,38:1,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,38:1,0 0,6,58:2,0 0,3,32:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,25:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,36:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 254 . T <*> 0 . DP=23;I16=13,10,0,0,803,28513,0,0,1380,82800,0,0,368,7832,0,0;QS=22,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,32:1,0 0,3,32:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,37:1,0 0,6,57:2,0 0,3,33:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,36:1,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 15 255 . G <*> 0 . DP=21;I16=11,10,0,0,809,31659,0,0,1260,75600,0,0,356,7558,0,0;QS=20,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,6,62:2,0 0,3,25:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,3,39:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 15 256 . G <*> 0 . DP=21;I16=11,10,0,0,827,32785,0,0,1260,75600,0,0,344,7308,0,0;QS=20,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,40:1,0 0,6,68:2,0 0,3,38:1,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,39:1,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 15 257 . A <*> 0 . DP=21;I16=11,10,0,0,701,24193,0,0,1260,75600,0,0,332,7082,0,0;QS=20,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,38:1,0 0,6,58:2,0 0,3,13:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,26:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,3,35:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 15 258 . T <*> 0 . DP=21;I16=11,10,0,0,742,26552,0,0,1260,75600,0,0,318,6782,0,0;QS=20,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,38:1,0 0,6,62:2,0 0,3,39:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,37:1,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 15 259 . T <*> 0 . DP=19;I16=10,9,0,0,657,23163,0,0,1140,68400,0,0,306,6508,0,0;QS=18,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,33:1,0 0,6,58:2,0 0,3,28:1,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 260 . G <*> 0 . DP=19;I16=10,9,0,0,724,28050,0,0,1140,68400,0,0,294,6258,0,0;QS=18,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,3,40:1,0 0,6,69:2,0 0,3,21:1,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 261 . T <*> 0 . DP=19;I16=10,9,0,0,641,22037,0,0,1140,68400,0,0,282,6032,0,0;QS=18,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,3,36:1,0 0,6,58:2,0 0,3,28:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,26:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 262 . C <*> 0 . DP=18;I16=9,9,0,0,668,25218,0,0,1080,64800,0,0,269,5731,0,0;QS=17,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,25:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,38:1,0 0,6,73:2,0 0,3,33:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 263 . T <*> 0 . DP=17;I16=8,9,0,0,615,22649,0,0,1020,61200,0,0,256,5406,0,0;QS=16,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,40:1,0 0,6,58:2,0 0,3,33:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 264 . G <*> 0 . DP=15;I16=8,7,0,0,572,22382,0,0,900,54000,0,0,245,5105,0,0;QS=14,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,20:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,40:1,0 0,6,67:2,0 0,3,38:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 265 . C <*> 0 . DP=14;I16=7,6,0,0,507,20059,0,0,780,46800,0,0,235,4825,0,0;QS=12,0;MQSB=0.961166;MQ0F=0 PL:AD 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,45:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,39:1,0 0,6,72:2,0 0,3,32:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 266 . T <*> 0 . DP=13;I16=7,6,0,0,482,18078,0,0,780,46800,0,0,224,4466,0,0;QS=12,0;MQSB=0.961166;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,40:1,0 0,6,58:2,0 0,3,33:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 267 . G <*> 0 . DP=13;I16=7,6,0,0,518,20762,0,0,780,46800,0,0,212,4080,0,0;QS=12,0;MQSB=0.961166;MQ0F=0 PL:AD 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,3,40:1,0 0,6,67:2,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 268 . C <*> 0 . DP=13;I16=7,6,0,0,507,19961,0,0,780,46800,0,0,200,3718,0,0;QS=12,0;MQSB=0.961166;MQ0F=0 PL:AD 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,39:1,0 0,6,72:2,0 0,3,34:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 269 . T <*> 0 . DP=13;I16=6,6,0,0,421,15155,0,0,720,43200,0,0,186,3376,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,3,32:1,0 0,6,55:2,0 0,3,23:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 270 . A <*> 0 . DP=12;I16=6,6,0,0,412,14406,0,0,720,43200,0,0,174,3016,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,3,28:1,0 0,6,60:2,0 0,3,31:1,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 271 . A <*> 0 . DP=12;I16=6,6,0,0,457,17551,0,0,720,43200,0,0,162,2680,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,38:1,0 0,6,65:2,0 0,3,38:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 272 . G <*> 0 . DP=12;I16=6,6,0,0,446,16980,0,0,720,43200,0,0,150,2368,0,0;QS=11,0;MQSB=0.982603;MQ0F=0 PL:AD 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,3,19:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,39:1,0 0,6,68:2,0 0,3,37:1,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 273 . T <*> 0 . DP=11;I16=6,5,0,0,361,12033,0,0,660,39600,0,0,139,2079,0,0;QS=10,0;MQSB=0.950952;MQ0F=0 PL:AD 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,26:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,3,36:1,0 0,6,56:2,0 0,3,32:1,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 274 . A <*> 0 . DP=11;I16=6,5,0,0,365,12297,0,0,660,39600,0,0,128,1812,0,0;QS=10,0;MQSB=0.950952;MQ0F=0 PL:AD 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,25:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,3,36:1,0 0,6,57:2,0 0,3,34:1,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 275 . T <*> 0 . DP=11;I16=6,5,0,0,352,11744,0,0,660,39600,0,0,117,1567,0,0;QS=10,0;MQSB=0.950952;MQ0F=0 PL:AD 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,23:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,3,37:1,0 0,6,56:2,0 0,3,18:1,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 276 . A <*> 0 . DP=10;I16=6,4,0,0,347,12321,0,0,600,36000,0,0,107,1343,0,0;QS=9,0;MQSB=1.00775;MQ0F=0 PL:AD 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,44:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,3,30:1,0 0,6,65:2,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 277 . G <*> 0 . DP=10;I16=5,4,0,0,327,12017,0,0,540,32400,0,0,88,1058,0,0;QS=8,0;MQSB=0.974597;MQ0F=0 PL:AD 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,3,39:1,0 0,6,59:2,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 278 . G <*> 0 . DP=10;I16=6,4,0,0,349,12519,0,0,600,36000,0,0,87,955,0,0;QS=9,0;MQSB=1.00775;MQ0F=0 PL:AD 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,30:1,0 0,6,58:2,0 0,0,0:0,0 0,3,27:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 279 . G <*> 0 . DP=10;I16=6,4,0,0,352,12680,0,0,600,36000,0,0,77,791,0,0;QS=9,0;MQSB=1.00775;MQ0F=0 PL:AD 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,3,30:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,43:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,3,25:1,0 0,6,62:2,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 280 . A <*> 0 . DP=9;I16=6,3,0,0,301,10219,0,0,540,32400,0,0,68,646,0,0;QS=9,0;MQSB=0.924584;MQ0F=0 PL:AD 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,3,27:1,0 0,3,33:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 281 . A <*> 0 . DP=9;I16=6,3,0,0,307,10609,0,0,540,32400,0,0,59,519,0,0;QS=9,0;MQSB=0.924584;MQ0F=0 PL:AD 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,37:1,0 0,3,33:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 282 . A <*> 0 . DP=9;I16=6,3,0,0,288,9572,0,0,540,32400,0,0,50,410,0,0;QS=9,0;MQSB=0.924584;MQ0F=0 PL:AD 0,0,0:0,0 0,3,17:1,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,3,38:1,0 0,3,30:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 283 . C <*> 0 . DP=7;I16=5,2,0,0,233,8233,0,0,420,25200,0,0,43,317,0,0;QS=7,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,31:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,3,37:1,0 0,3,39:1,0 0,0,0:0,0 0,3,15:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 284 . A <*> 0 . DP=7;I16=5,2,0,0,247,8783,0,0,420,25200,0,0,36,238,0,0;QS=7,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,42:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,3,36:1,0 0,3,35:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 285 . G <*> 0 . DP=7;I16=5,2,0,0,262,9826,0,0,420,25200,0,0,29,173,0,0;QS=7,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,36:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,3,38:1,0 0,3,38:1,0 0,0,0:0,0 0,3,38:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 286 . T <*> 0 . DP=7;I16=5,2,0,0,237,8129,0,0,420,25200,0,0,22,122,0,0;QS=7,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,41:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,3,36:1,0 0,3,34:1,0 0,0,0:0,0 0,3,35:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 287 . T <*> 0 . DP=5;I16=3,2,0,0,171,5905,0,0,300,18000,0,0,17,83,0,0;QS=5,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,35:1,0 0,3,30:1,0 0,0,0:0,0 0,3,34:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 288 . A <*> 0 . DP=4;I16=2,2,0,0,134,4534,0,0,240,14400,0,0,13,53,0,0;QS=4,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,39:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,30:1,0 0,0,0:0,0 0,3,32:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 289 . T <*> 0 . DP=4;I16=2,2,0,0,130,4276,0,0,240,14400,0,0,9,31,0,0;QS=4,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,37:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,3,27:1,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 290 . A <*> 0 . DP=4;I16=2,2,0,0,131,4369,0,0,240,14400,0,0,5,17,0,0;QS=4,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,40:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,32:1,0 0,3,31:1,0 0,0,0:0,0 0,3,28:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 291 . G <*> 0 . DP=2;I16=1,1,0,0,55,1573,0,0,120,7200,0,0,3,9,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,22:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,33:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 292 . C <*> 0 . DP=1;I16=1,0,0,0,24,576,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,24:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 293 . T <*> 0 . DP=1;I16=1,0,0,0,20,400,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,20:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 15 294 . G <*> 0 . DP=1;I16=1,0,0,0,29,841,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:AD 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,3,29:1,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 0,0,0:0,0 bcftools-1.21/test/mpileup.ped000066400000000000000000000001101467060157400163760ustar00rootroot00000000000000HG00100 HG00100 0 0 2 0 HG00101 HG00101 0 0 1 0 HG00102 HG00102 0 0 2 0 bcftools-1.21/test/mpileup.ploidy000066400000000000000000000000611467060157400171330ustar00rootroot00000000000000X 1 1000 M 1 X 3104 5000 M 1 * * * M 2 * * * F 2 bcftools-1.21/test/mpileup.samples000066400000000000000000000000361467060157400173010ustar00rootroot00000000000000HG00100 F HG00101 M HG00102 F bcftools-1.21/test/mpileup.tab000066400000000000000000000001771467060157400164110ustar00rootroot0000000000000017 1 A,G,T 17 2 A,T,G 17 3 A,C 17 4 A,C,T,G 17 5 A,G,T 17 6 A,T,G 17 7 A,T,G,C 17 828 T,C 17 1665 T,C 17 2220 G,C 17 2564 A,AG bcftools-1.21/test/mpileup.vcf000066400000000000000000023605561467060157400164350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 ##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz ##reference=file://xxx//mpileup.ref.fa.gz ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 1 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0,.,.,.,.,.,.,.,.,.:5:0 .:3:0 .:3:0 17 2 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0,.,.,.,.,.,.,.,.,.:5:0 .:3:0 .:3:0 17 3 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0,.,.,.,.,.,.,.,.,.:5:0 .:3:0 .:3:0 17 4 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:5:0 .:3:0 .:3:0 17 5 . A X,G 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,0,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0:5:0 .:3:0 .:3:0 17 6 . A X,G 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,0,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0:5:0 .:3:0 .:3:0 17 7 . A X,G 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,0,1;MQ0F=0 PL:DP:DV 1,2,3,4,5,6:5:0 .:3:0 .:3:0 17 8 . T 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 9 . C 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 10 . A 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 17 11 . C 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 12 . C 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 13 . C 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 14 . T 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 15 . G 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 16 . T 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 17 . T 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 17 18 . C 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 17 19 . C 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 17 20 . T 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 17 21 . G 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 17 22 . C 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 17 23 . A 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 17 24 . T 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 17 25 . A 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 17 26 . G 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 17 27 . A 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 17 28 . T 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 17 29 . A 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 17 30 . A 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 17 31 . T 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 17 32 . T 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 17 33 . G 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 17 34 . C 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 17 35 . A 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 17 36 . T 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 17 37 . G 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 17 38 . A 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 17 39 . C 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 17 40 . A 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 17 41 . A 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 17 42 . T 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 17 43 . T 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 17 44 . G 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 17 45 . C 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 17 46 . C 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 17 47 . T 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 17 48 . T 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 17 49 . G 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 17 50 . T 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 17 51 . C 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 17 52 . C 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 17 53 . C 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 17 54 . T 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 17 55 . G 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 17 56 . C 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 17 57 . T 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 17 58 . G 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 17 59 . A 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 17 60 . A 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 17 61 . T 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 17 62 . G 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 17 63 . T 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 17 64 . G 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 17 65 . C 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 17 66 . T 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 17 67 . C 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 17 68 . T 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 17 69 . G 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 17 70 . G 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 17 71 . G 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 17 72 . G 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 17 73 . T 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 17 74 . C 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 17 75 . T 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 17 76 . C 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 17 77 . T 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 17 78 . G 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 17 79 . G 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 17 80 . G 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 17 81 . G 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 17 82 . T 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 17 83 . C 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 17 84 . T 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 17 85 . C 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 17 86 . A 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 17 87 . C 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 17 88 . C 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 17 89 . C 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 17 90 . A 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 17 91 . C 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 17 92 . G 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 17 93 . A 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 17 94 . C 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 17 95 . C 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 17 96 . A 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 17 97 . A 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 17 98 . C 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 17 99 . T 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 17 100 . C 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 17 101 . C 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 17 102 . C 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 17 103 . T 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 17 104 . G 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 17 105 . G 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 17 106 . G 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 17 107 . C 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 17 108 . C 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 17 109 . T 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 17 110 . G 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 17 111 . G 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 17 112 . C 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 17 113 . A 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 17 114 . C 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 17 115 . C 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 17 116 . A 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 17 117 . G 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 17 118 . G 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 17 119 . G 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 17 120 . A 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 17 121 . G 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 17 122 . C 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 17 123 . T 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 17 124 . T 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 17 125 . A 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 17 126 . A 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 17 127 . C 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 17 128 . A 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 17 129 . A 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 17 130 . A 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 17 131 . C 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 17 132 . A 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 17 133 . T 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 17 134 . C 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 17 135 . T 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 17 136 . G 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 17 137 . T 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 17 138 . C 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 17 139 . C 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 17 140 . A 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 17 141 . G 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 17 142 . C 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 17 143 . G 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 17 144 . A 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 17 145 . A 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 17 146 . T 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 17 147 . A 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 17 148 . C 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 17 149 . C 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 17 150 . T 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 17 151 . G 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 17 152 . C 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 17 153 . A 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 17 154 . T 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 17 155 . C 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 17 156 . C 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 17 157 . C 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 17 158 . T 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 17 159 . A 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 17 160 . G 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 17 161 . A 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 17 162 . A 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 17 163 . G 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 17 164 . T 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 17 165 . G 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 17 166 . A 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 17 167 . A 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 17 168 . G 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 17 169 . C 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 17 170 . C 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 17 171 . A 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 17 172 . C 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 17 173 . C 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 17 174 . G 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 17 175 . C 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 17 176 . C 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 17 177 . C 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 17 178 . A 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 17 179 . A 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 17 180 . A 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 17 181 . G 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 17 182 . A 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 17 183 . C 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 17 184 . A 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 17 185 . C 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 17 186 . G 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 17 187 . C 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 17 188 . C 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 17 189 . C 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 17 190 . A 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 17 191 . T 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 17 192 . G 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 17 193 . T 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 17 194 . C 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 17 195 . C 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 17 196 . A 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 17 197 . G 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 17 198 . C 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 17 199 . T 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 17 200 . T 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 17 201 . A 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 17 202 . A 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 17 203 . C 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 17 204 . C 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 17 205 . T 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 17 206 . G 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 17 207 . C 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 17 208 . A 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 17 209 . T 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 17 210 . C 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 17 211 . C 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 17 212 . C 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 17 213 . T 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 17 214 . A 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 17 215 . G 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 17 216 . A 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 17 217 . A 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 17 218 . G 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 17 219 . T 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 17 220 . G 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 17 221 . A 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 17 222 . A 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 17 223 . G 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 17 224 . G 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 17 225 . C 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 17 226 . A 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 17 227 . C 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 17 228 . C 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 17 229 . G 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 17 230 . C 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 17 231 . C 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 17 232 . C 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 17 233 . A 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 17 234 . A 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 17 235 . A 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 17 236 . G 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 17 237 . A 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 17 238 . C 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 17 239 . A 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 17 240 . C 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 17 241 . G 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 17 242 . C 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 17 243 . C 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 17 244 . C 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 17 245 . A 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 17 246 . T 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 17 247 . G 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 17 248 . T 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 17 249 . C 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 17 250 . C 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 17 251 . A 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 17 252 . G 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 17 253 . C 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 17 254 . T 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 17 255 . T 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 17 256 . A 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 17 257 . T 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 17 258 . T 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 17 259 . C 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 17 260 . T 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 17 261 . G 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 17 262 . C 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 17 263 . C 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 17 264 . C 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 17 265 . A 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 17 266 . G 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 17 267 . T 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 17 268 . T 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 17 269 . C 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 17 270 . C 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 17 271 . T 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 17 272 . C 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 17 273 . T 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 17 274 . C 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 17 275 . C 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 17 276 . A 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 17 277 . G 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 17 278 . A 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 17 279 . A 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 17 280 . A 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 17 281 . G 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 17 282 . G 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 17 283 . C 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 17 284 . T 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 17 285 . G 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 17 286 . C 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 17 287 . A 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 17 288 . T 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 17 289 . G 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 17 290 . G 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 17 291 . T 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 17 292 . T 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 17 293 . G 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 17 294 . A 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 17 295 . C 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 17 296 . A 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 17 297 . C 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 17 298 . A 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 17 299 . C 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 17 300 . A 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 17 301 . G 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 17 302 . T 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 17 303 . G 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 17 304 . C 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 17 305 . C 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 17 306 . T 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 17 307 . G 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 17 308 . C 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 17 309 . G 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 17 310 . A 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 17 311 . C 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 17 312 . A 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 17 313 . A 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 17 314 . A 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 17 315 . G 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 17 316 . C 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 17 317 . T 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 17 318 . G 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 17 319 . A 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 17 320 . A 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 17 321 . T 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 17 322 . G 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 17 323 . C 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 17 324 . T 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 17 325 . A 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 17 326 . T 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 17 327 . C 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 17 328 . A 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 17 329 . T 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 17 330 . T 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 17 331 . T 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 17 332 . A 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 17 333 . A 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 17 334 . A 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 17 335 . A 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 17 336 . A 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 17 337 . C 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 17 338 . T 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 17 339 . C 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 17 340 . C 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 17 341 . T 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 17 342 . T 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 17 343 . G 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 17 344 . C 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 17 345 . T 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 17 346 . G 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 17 347 . G 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 17 348 . T 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 17 349 . T 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 17 350 . T 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 17 351 . G 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 17 352 . A 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 17 353 . G 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 17 354 . A 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 17 355 . G T, 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 17 356 . G 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 17 357 . C 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 17 358 . A 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 17 359 . G 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 17 360 . A 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 17 361 . A 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 17 362 . A 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 17 363 . A 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 17 364 . T 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 17 365 . G 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 17 366 . A 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 17 367 . T 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 17 368 . A 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 17 369 . T 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 17 370 . C 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 17 371 . T 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 17 372 . C 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 17 373 . A 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 17 374 . T 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 17 375 . A T, 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 17 376 . G 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 17 377 . T 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 17 378 . T 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 17 379 . G 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 17 380 . C 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 17 381 . T 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 17 382 . T 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 17 383 . T 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 17 384 . A 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 17 385 . C 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 17 386 . T 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 17 387 . T 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 17 388 . T 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 17 389 . G 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 17 390 . C 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 17 391 . A 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 17 392 . T 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 17 393 . A 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 17 394 . T 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 17 395 . T 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 17 396 . T 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 17 397 . T 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 17 398 . A 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 17 399 . A 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 17 400 . A 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 17 401 . A 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 17 402 . T 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 17 403 . T 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 17 404 . G 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 17 405 . T 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 17 406 . G 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 17 407 . A 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 17 408 . C 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 17 409 . T 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 17 410 . T 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 17 411 . T 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 17 412 . C T, 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 17 413 . A 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 17 414 . T 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 17 415 . G 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 17 416 . G 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 17 417 . C 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 17 418 . A 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 17 419 . T 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 17 420 . A 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 17 421 . A 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 17 422 . A 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 17 423 . T 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 17 424 . A 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 17 425 . A 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 17 426 . T 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 17 427 . A 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 17 428 . C 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 17 429 . T 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 17 430 . G 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 17 431 . G 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 17 432 . T 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 17 433 . T 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 17 434 . T 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 17 435 . A 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 17 436 . T 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 17 437 . T 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 17 438 . A 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 17 439 . C 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 17 440 . A 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 17 441 . G 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 17 442 . A 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 17 443 . A 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 17 444 . G 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 17 445 . C 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 17 446 . A 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 17 447 . C 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 17 448 . T 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 17 449 . A 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 17 450 . G 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 17 451 . A 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 17 452 . A 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 17 453 . A 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 17 454 . A 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 17 455 . T 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 17 456 . G 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 17 457 . C 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 17 458 . A 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 17 459 . T 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 17 460 . G 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 17 461 . T 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 17 462 . G 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 17 463 . G 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 17 464 . A 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 17 465 . C 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 17 466 . A 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 17 467 . A 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 17 468 . A 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 17 469 . A 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 17 470 . G 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 17 471 . T 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 17 472 . T 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 17 473 . G 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 17 474 . G 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 17 475 . G 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 17 476 . A 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 17 477 . T 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 17 478 . T 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 17 479 . A 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 17 480 . G 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 17 481 . G 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 17 482 . A 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 17 483 . G 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 17 484 . A 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 17 485 . G 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 17 486 . A 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 17 487 . G 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 17 488 . A 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 17 489 . A 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 17 490 . A 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 17 491 . T 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 17 492 . G 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 17 493 . A 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 17 494 . A 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 17 495 . G 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 17 496 . A 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 17 497 . C 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 17 498 . A 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 17 499 . T 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 17 500 . A 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 17 501 . T 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 17 502 . G 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 17 503 . T 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 17 504 . C 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 17 505 . C 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 17 506 . A 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 17 507 . C 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 17 508 . A 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 17 509 . C 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 17 510 . A 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 17 511 . A 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 17 512 . A C, 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 17 513 . A 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 17 514 . A T, 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 17 515 . C 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 17 516 . C 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 17 517 . T 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 17 518 . G 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 17 519 . T 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 17 520 . T 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 17 521 . C 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 17 522 . A 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 17 523 . T G, 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 17 524 . T 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 17 525 . G 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 17 526 . C 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 17 527 . A 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 17 528 . G 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 17 529 . C 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 17 530 . T 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 17 531 . T 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 17 532 . T 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 17 533 . C 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 17 534 . T 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 17 535 . A 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 17 536 . C 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 17 537 . C 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 17 538 . A 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 17 539 . T 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 17 540 . C 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 17 541 . A 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 17 542 . C 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 17 543 . C 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 17 544 . A 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 17 545 . A 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 17 546 . A 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 17 547 . A 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 17 548 . A 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 17 549 . T G, 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 17 550 . T 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 17 551 . G 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 17 552 . C 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 17 553 . A 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 17 554 . A 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 17 555 . A 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 17 556 . C 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 17 557 . A 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 17 558 . A 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 17 559 . C A, 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 17 560 . C 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 17 561 . A 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 17 562 . C 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 17 563 . A 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 17 564 . C 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 17 565 . G 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 17 566 . C 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 17 567 . C 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 17 568 . C 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 17 569 . T 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 17 570 . T 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 17 571 . C 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 17 572 . A 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 17 573 . A 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 17 574 . C A, 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 17 575 . T 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 17 576 . G 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 17 577 . G 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 17 578 . G 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 17 579 . G 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 17 580 . A C, 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 17 581 . A 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 17 582 . C 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 17 583 . T 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 17 584 . C 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 17 585 . A 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 17 586 . T 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 17 587 . C 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 17 588 . A 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 17 589 . A 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 17 590 . C 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 17 591 . A 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 17 592 . A 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 17 593 . C 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 17 594 . A 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 17 595 . A 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 17 596 . A 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 17 597 . C 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 17 598 . T 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 17 599 . T 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 17 600 . G 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 17 601 . T 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 17 602 . G 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 17 603 . G 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 17 604 . T 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 17 605 . T 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 17 606 . T 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 17 607 . A 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 17 608 . C 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 17 609 . C 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 17 610 . C 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 17 611 . A 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 17 612 . C 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 17 613 . A 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 17 614 . C 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 17 615 . A 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 17 616 . A 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 17 617 . T 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 17 618 . G 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 17 619 . G 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 17 620 . A 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 17 621 . A 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 17 622 . G 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 17 623 . A T, 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 17 624 . C 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 17 625 . C 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 17 626 . A 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 17 627 . C 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 17 628 . T 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 17 629 . T 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 17 630 . A 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 17 631 . G 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 17 632 . C 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 17 633 . A 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 17 634 . A 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 17 635 . C 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 17 636 . A 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 17 637 . A 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 17 638 . A 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 17 639 . A 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 17 640 . A 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 17 641 . G 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 17 642 . G 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 17 643 . A 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 17 644 . C A, 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 17 645 . C 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 17 646 . A T, 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 17 647 . A 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 17 648 . A 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 17 649 . C 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 17 650 . T 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 17 651 . C 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 17 652 . C 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 17 653 . T 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 17 654 . G 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 17 655 . G 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 17 656 . T 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 17 657 . A 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 17 658 . C 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 17 659 . A 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 17 660 . T 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 17 661 . G 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 17 662 . C 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 17 663 . A 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 17 664 . A 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 17 665 . C 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 17 666 . T 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 17 667 . G 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 17 668 . A 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 17 669 . C 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 17 670 . A 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 17 671 . G 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 17 672 . A 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 17 673 . T 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 17 674 . G 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 17 675 . A 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 17 676 . A 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 17 677 . T 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 17 678 . C 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 17 679 . T 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 17 680 . C 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 17 681 . A 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 17 682 . A 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 17 683 . A 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 17 684 . C 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 17 685 . G 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 17 686 . C 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 17 687 . A 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 17 688 . T 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 17 689 . T A, 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 17 690 . C 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 17 691 . C 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 17 692 . T 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 17 693 . C 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 17 694 . C 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 17 695 . G 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 17 696 . T 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 17 697 . G 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 17 698 . T 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 17 699 . G 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 17 700 . A 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 17 701 . A 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 17 702 . A 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 17 703 . G 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 17 704 . A T, 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 17 705 . A 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 17 706 . G 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 17 707 . C 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 17 708 . C 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 17 709 . G 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 17 710 . G 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 17 711 . A 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 17 712 . C 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 17 713 . T 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 17 714 . C 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 17 715 . A 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 17 716 . C 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 17 717 . A 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 17 718 . G 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 17 719 . G 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 17 720 . G 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 17 721 . C 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 17 722 . A 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 17 723 . A 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 17 724 . C 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 17 725 . A 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 17 726 . C 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 17 727 . A C, 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 17 728 . C 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 17 729 . T 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 17 730 . A 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 17 731 . T 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 17 732 . C 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 17 733 . T 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 17 734 . G 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 17 735 . A 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 17 736 . C 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 17 737 . T 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 17 738 . G 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 17 739 . T 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 17 740 . T 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 17 741 . T 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 17 742 . C 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 17 743 . A 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 17 744 . T 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 17 745 . G 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 17 746 . G 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 17 747 . G 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 17 748 . A 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 17 749 . A 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 17 750 . A 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 17 751 . G 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 17 752 . T 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 17 753 . C 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 17 754 . T 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 17 755 . G 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 17 756 . G 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 17 757 . A 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 17 758 . A 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 17 759 . A 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 17 760 . C 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 17 761 . G 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 17 762 . G 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 17 763 . C A, 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 17 764 . A 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 17 765 . A 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 17 766 . C 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 17 767 . A 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 17 768 . C 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 17 769 . C 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 17 770 . A 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 17 771 . T 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 17 772 . T 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 17 773 . G 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 17 774 . A 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 17 775 . G 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 17 776 . A 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 17 777 . C 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 17 778 . A 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 17 779 . G 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 17 780 . A 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 17 781 . A 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 17 782 . A 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 17 783 . A 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 17 784 . C 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 17 785 . A 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 17 786 . G 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 17 787 . G 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 17 788 . T 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 17 789 . G 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 17 790 . A 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 17 791 . G 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 17 792 . T 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 17 793 . G 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 17 794 . G 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 17 795 . T 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 17 796 . T 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 17 797 . G 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 17 798 . C 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 17 799 . C 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 17 800 . T 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 17 801 . G 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 17 802 . G 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 17 803 . G 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 17 804 . G 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 17 805 . C 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 17 806 . C 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 17 807 . A 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 17 808 . G 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 17 809 . G 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 17 810 . G C, 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 17 811 . A 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 17 812 . A 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 17 813 . C 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 17 814 . T 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 17 815 . T 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 17 816 . T 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 17 817 . C 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 17 818 . T 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 17 819 . G 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 17 820 . G 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 17 821 . G 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 17 822 . G 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 17 823 . T 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 17 824 . C 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 17 825 . A 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 17 826 . T 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 17 827 . A 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 17 828 . T C, 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 17 829 . T 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 17 830 . C 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 17 831 . T 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 17 832 . C 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 17 833 . T 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 17 834 . G A, 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 17 835 . T 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 17 836 . G 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 17 837 . T 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 17 838 . T 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 17 839 . G 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 17 840 . A 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 17 841 . T 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 17 842 . T 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 17 843 . C 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 17 844 . T 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 17 845 . G 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 17 846 . G 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 17 847 . T 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 17 848 . G 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 17 849 . G 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 17 850 . T 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 17 851 . G 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 17 852 . G 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 17 853 . A 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 17 854 . A 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 17 855 . A 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 17 856 . C 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 17 857 . A 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 17 858 . A 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 17 859 . G 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 17 860 . A 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 17 861 . C 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 17 862 . T 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 17 863 . G 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 17 864 . T 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 17 865 . C 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 17 866 . C 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 17 867 . C 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 17 868 . A 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 17 869 . G 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 17 870 . C 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 17 871 . C 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 17 872 . T 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 17 873 . G 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 17 874 . G 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 17 875 . G 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 17 876 . T 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 17 877 . G 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 17 878 . A 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 17 879 . T 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 17 880 . A 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 17 881 . C 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 17 882 . A 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 17 883 . G 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 17 884 . C 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 17 885 . G 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 17 886 . A 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 17 887 . G 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 17 888 . A 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 17 889 . C 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 17 890 . C 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 17 891 . C 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 17 892 . C 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 17 893 . A 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 17 894 . T 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 17 895 . C 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 17 896 . T 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 17 897 . C 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 17 898 . T 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 17 899 . A 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 17 900 . C 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 17 901 . C 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 17 902 . A 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 17 903 . A 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 17 904 . A 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 17 905 . A 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 17 906 . A 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 17 907 . A 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 17 908 . T 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 17 909 . T 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 17 910 . A 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 17 911 . A 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 17 912 . A 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 17 913 . A 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 17 914 . A 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 17 915 . T 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 17 916 . T 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 17 917 . A 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 17 918 . G 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 17 919 . C 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 17 920 . T 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 17 921 . G 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 17 922 . G 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 17 923 . G 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 17 924 . C 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 17 925 . A 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 17 926 . T 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 17 927 . G 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 17 928 . G 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 17 929 . T 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 17 930 . G 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 17 931 . G 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 17 932 . T 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 17 933 . G 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 17 934 . C 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 17 935 . A 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 17 936 . T 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 17 937 . G 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 17 938 . C 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 17 939 . C 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 17 940 . T 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 17 941 . G 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 17 942 . T 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 17 943 . A 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 17 944 . G 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 17 945 . T 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 17 946 . C 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 17 947 . C 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 17 948 . C 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 17 949 . A 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 17 950 . G 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 17 951 . C 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 17 952 . T 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 17 953 . A 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 17 954 . T 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 17 955 . T 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 17 956 . C 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 17 957 . A 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 17 958 . C 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 17 959 . A 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 17 960 . G 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 17 961 . T 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 17 962 . G 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 17 963 . C 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 17 964 . T 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 17 965 . G 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 17 966 . A 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 17 967 . G 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 17 968 . G 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 17 969 . T 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 17 970 . G 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 17 971 . G 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 17 972 . G 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 17 973 . A 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 17 974 . A 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 17 975 . G 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 17 976 . A 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 17 977 . T 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 17 978 . G 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 17 979 . C 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 17 980 . T 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 17 981 . T 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 17 982 . G 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 17 983 . A 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 17 984 . G 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 17 985 . C 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 17 986 . C A, 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 17 987 . C 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 17 988 . A 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 17 989 . G 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 17 990 . G 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 17 991 . A 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 17 992 . G 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 17 993 . T 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 17 994 . T 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 17 995 . C 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 17 996 . A 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 17 997 . A 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 17 998 . G 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 17 999 . G 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 17 1000 . C 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 17 1001 . T 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 17 1002 . G 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 17 1003 . C T, 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 17 1004 . A 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 17 1005 . A 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 17 1006 . T 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 17 1007 . G 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 17 1008 . A 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 17 1009 . G 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 17 1010 . C 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 17 1011 . T 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 17 1012 . A 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 17 1013 . T 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 17 1014 . G 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 17 1015 . A 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 17 1016 . T 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 17 1017 . T 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 17 1018 . G 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 17 1019 . C 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 17 1020 . G 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 17 1021 . C 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 17 1022 . C 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 17 1023 . A 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 17 1024 . C 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 17 1025 . T 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 17 1026 . G 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 17 1027 . C 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 17 1028 . A 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 17 1029 . C 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 17 1030 . T 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 17 1031 . T 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 17 1032 . T 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 17 1033 . G 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 17 1034 . G 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 17 1035 . C 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 17 1036 . C 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 17 1037 . T 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 17 1038 . G 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 17 1039 . G 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 17 1040 . A 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 17 1041 . C 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 17 1042 . A 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 17 1043 . A 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 17 1044 . C 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 17 1045 . A 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 17 1046 . G 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 17 1047 . A 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 17 1048 . G 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 17 1049 . C 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 17 1050 . A 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 17 1051 . A 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 17 1052 . A 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 17 1053 . A 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 17 1054 . C 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 17 1055 . C 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 17 1056 . C 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 17 1057 . T 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 17 1058 . G 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 17 1059 . T 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 17 1060 . C 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 17 1061 . T 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 17 1062 . C A, 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 17 1063 . T 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 17 1064 . A 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 17 1065 . A 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 17 1066 . A 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 17 1067 . A 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 17 1068 . A 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 17 1069 . A 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 17 1070 . A 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 17 1071 . G 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 17 1072 . A 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 17 1073 . A 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 17 1074 . A 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 17 1075 . A 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 17 1076 . G 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 17 1077 . A 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 17 1078 . A 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 17 1079 . A 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 17 1080 . A 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 17 1081 . G 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 17 1082 . A 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 17 1083 . A 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 17 1084 . A 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 17 1085 . A 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 17 1086 . A 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 17 1087 . C 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 17 1088 . T 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 17 1089 . C 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 17 1090 . A 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 17 1091 . C 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 17 1092 . T 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 17 1093 . G 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 17 1094 . G 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 17 1095 . A 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 17 1096 . T 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 17 1097 . A 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 17 1098 . T 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 17 1099 . G 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 17 1100 . A 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 17 1101 . A 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 17 1102 . T 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 17 1103 . G 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 17 1104 . A 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 17 1105 . T 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 17 1106 . A 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 17 1107 . C 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 17 1108 . A 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 17 1109 . G 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 17 1110 . G 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 17 1111 . T 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 17 1112 . T 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 17 1113 . G 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 17 1114 . A 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 17 1115 . G 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 17 1116 . G 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 17 1117 . A 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 17 1118 . T 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 17 1119 . C 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 17 1120 . C 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 17 1121 . A 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 17 1122 . T 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 17 1123 . T 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 17 1124 . A 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 17 1125 . T 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 17 1126 . C 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 17 1127 . T 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 17 1128 . G 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 17 1129 . A G, 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 17 1130 . A 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 17 1131 . A 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 17 1132 . T 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 17 1133 . G 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 17 1134 . C 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 17 1135 . T 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 17 1136 . T 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 17 1137 . G 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 17 1138 . G 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 17 1139 . A 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 17 1140 . C 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 17 1141 . C 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 17 1142 . A 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 17 1143 . G 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 17 1144 . A 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 17 1145 . T 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 17 1146 . G 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 17 1147 . T 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 17 1148 . T 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 17 1149 . T 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 17 1150 . T 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 17 1151 . G 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 17 1152 . A 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 17 1153 . A 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 17 1154 . T 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 17 1155 . T 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 17 1156 . T 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 17 1157 . T 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 17 1158 . G 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 17 1159 . G 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 17 1160 . A 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 17 1161 . T 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 17 1162 . T 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 17 1163 . T 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 17 1164 . T 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 17 1165 . T 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 17 1166 . T 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 17 1167 . C 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 17 1168 . A 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 17 1169 . T 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 17 1170 . A 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 17 1171 . T 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 17 1172 . T 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 17 1173 . T 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 17 1174 . T 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 17 1175 . G 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 17 1176 . T 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 17 1177 . A 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 17 1178 . A 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 17 1179 . T 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 17 1180 . C 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 17 1181 . T 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 17 1182 . T 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 17 1183 . T 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 17 1184 . G 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 17 1185 . C 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 17 1186 . A 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 17 1187 . G 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 17 1188 . T 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 17 1189 . A 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 17 1190 . T 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 17 1191 . A 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 17 1192 . T 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 17 1193 . T 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 17 1194 . T 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 17 1195 . A 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 17 1196 . C 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 17 1197 . C 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 17 1198 . A 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 17 1199 . G 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 17 1200 . T 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 17 1201 . T 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 17 1202 . C 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 17 1203 . A 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 17 1204 . G 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 17 1205 . C 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 17 1206 . A 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 17 1207 . T 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 17 1208 . C 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 17 1209 . C T, 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 17 1210 . C 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 17 1211 . T 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 17 1212 . A 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 17 1213 . A 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 17 1214 . C 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 17 1215 . T 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 17 1216 . C 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 17 1217 . A 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 17 1218 . A 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 17 1219 . A 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 17 1220 . A 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 17 1221 . A 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 17 1222 . T 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 17 1223 . T 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 17 1224 . C 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 17 1225 . A 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 17 1226 . A 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 17 1227 . A 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 17 1228 . A 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 17 1229 . A 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 17 1230 . T 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 17 1231 . C 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 17 1232 . T 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 17 1233 . G 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 17 1234 . A 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 17 1235 . A 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 17 1236 . A 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 17 1237 . T 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 17 1238 . C 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 17 1239 . C 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 17 1240 . C 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 17 1241 . A 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 17 1242 . A 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 17 1243 . A 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 17 1244 . C 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 17 1245 . G 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 17 1246 . C 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 17 1247 . G 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 17 1248 . C 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 17 1249 . C 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 17 1250 . A 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 17 1251 . A 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 17 1252 . T 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 17 1253 . A 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 17 1254 . A 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 17 1255 . G 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 17 1256 . C 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 17 1257 . A 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 17 1258 . T 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 17 1259 . T 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 17 1260 . C 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 17 1261 . C 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 17 1262 . C 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 17 1263 . T 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 17 1264 . T 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 17 1265 . T 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 17 1266 . G 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 17 1267 . A 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 17 1268 . G 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 17 1269 . C 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 17 1270 . G 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 17 1271 . T 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 17 1272 . C 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 17 1273 . A 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 17 1274 . T 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 17 1275 . G 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 17 1276 . T 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 17 1277 . C 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 17 1278 . G 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 17 1279 . G 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 17 1280 . T 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 17 1281 . G 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 17 1282 . C 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 17 1283 . T 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 17 1284 . T 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 17 1285 . G 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 17 1286 . G 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 17 1287 . A 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 17 1288 . A 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 17 1289 . T 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 17 1290 . G 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 17 1291 . T 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 17 1292 . T 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 17 1293 . T 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 17 1294 . G 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 17 1295 . G 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 17 1296 . G 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 17 1297 . G 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 17 1298 . T 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 17 1299 . T 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 17 1300 . T 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 17 1301 . T G, 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 17 1302 . G 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 17 1303 . G 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 17 1304 . A 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 17 1305 . T 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 17 1306 . T 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 17 1307 . T 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 17 1308 . A 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 17 1309 . C 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 17 1310 . A 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 17 1311 . G 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 17 1312 . C 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 17 1313 . T 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 17 1314 . T 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 17 1315 . T 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 17 1316 . G 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 17 1317 . G 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 17 1318 . G 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 17 1319 . A 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 17 1320 . C 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 17 1321 . G 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 17 1322 . C 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 17 1323 . T 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 17 1324 . C 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 17 1325 . A 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 17 1326 . A 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 17 1327 . C 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 17 1328 . C 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 17 1329 . T 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 17 1330 . G 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 17 1331 . T 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 17 1332 . A 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 17 1333 . C 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 17 1334 . C 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 17 1335 . T 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 17 1336 . C 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 17 1337 . A 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 17 1338 . A 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 17 1339 . T 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 17 1340 . A 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 17 1341 . A 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 17 1342 . A 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 17 1343 . C 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 17 1344 . C 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 17 1345 . T 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 17 1346 . G 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 17 1347 . A 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 17 1348 . T 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 17 1349 . T 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 17 1350 . T 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 17 1351 . T 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 17 1352 . A 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 17 1353 . A 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 17 1354 . A 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 17 1355 . A 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 17 1356 . A 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 17 1357 . A 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 17 1358 . G 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 17 1359 . T 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 17 1360 . T 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 17 1361 . T 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 17 1362 . G 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 17 1363 . G 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 17 1364 . G 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 17 1365 . G 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 17 1366 . G 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 17 1367 . G C, 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 17 1368 . A 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 17 1369 . T 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 17 1370 . T 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 17 1371 . C 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 17 1372 . C 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 17 1373 . C 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 17 1374 . C 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 17 1375 . T 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 17 1376 . A 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 17 1377 . A 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 17 1378 . G 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 17 1379 . C 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 17 1380 . C 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 17 1381 . C 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 17 1382 . G 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 17 1383 . C 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 17 1384 . C 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 17 1385 . A 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 17 1386 . C 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 17 1387 . C 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 17 1388 . C 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 17 1389 . G 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 17 1390 . G 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 17 1391 . A 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 17 1392 . G 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 17 1393 . A 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 17 1394 . C 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 17 1395 . A 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 17 1396 . G 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 17 1397 . C 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 17 1398 . G 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 17 1399 . G 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 17 1400 . A 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 17 1401 . T 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 17 1402 . T 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 17 1403 . T 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 17 1404 . C 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 17 1405 . C 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 17 1406 . T 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 17 1407 . T 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 17 1408 . A 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 17 1409 . G 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 17 1410 . T 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 17 1411 . T 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 17 1412 . A T, 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 17 1413 . C 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 17 1414 . T 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 17 1415 . T 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 17 1416 . A 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 17 1417 . C 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 17 1418 . T 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 17 1419 . A 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 17 1420 . T 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 17 1421 . G 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 17 1422 . C 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 17 1423 . T 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 17 1424 . C 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 17 1425 . C 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 17 1426 . T 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 17 1427 . T 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 17 1428 . G 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 17 1429 . G 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 17 1430 . C 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 17 1431 . C 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 17 1432 . A 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 17 1433 . T 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 17 1434 . T 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 17 1435 . T 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 17 1436 . C 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 17 1437 . T 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 17 1438 . C 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 17 1439 . T 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 17 1440 . A 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 17 1441 . G 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 17 1442 . G 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 17 1443 . T 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 17 1444 . A 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 17 1445 . T 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 17 1446 . T 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 17 1447 . G 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 17 1448 . G 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 17 1449 . T 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 17 1450 . A 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 17 1451 . T 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 17 1452 . A 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 17 1453 . T 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 17 1454 . T 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 17 1455 . G 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 17 1456 . T 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 17 1457 . G 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 17 1458 . T 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 17 1459 . C A, 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 17 1460 . T 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 17 1461 . G 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 17 1462 . C 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 17 1463 . T 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 17 1464 . G 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 17 1465 . T 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 17 1466 . G 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 17 1467 . A 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 17 1468 . A 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 17 1469 . C T, 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 17 1470 . T 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 17 1471 . G 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 17 1472 . T 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 17 1473 . C 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 17 1474 . C 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 17 1475 . T 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 17 1476 . T G, 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 17 1477 . G 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 17 1478 . G 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 17 1479 . C 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 17 1480 . C 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 17 1481 . T 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 17 1482 . G 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 17 1483 . T 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 17 1484 . T 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 17 1485 . T 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 17 1486 . G 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 17 1487 . G 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 17 1488 . T 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 17 1489 . G 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 17 1490 . A 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 17 1491 . C 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 17 1492 . G 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 17 1493 . G 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 17 1494 . G 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 17 1495 . T 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 17 1496 . G 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 17 1497 . A 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 17 1498 . G 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 17 1499 . G 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 17 1500 . A 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 17 1501 . G 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 17 1502 . C 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 17 1503 . A 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 17 1504 . G 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 17 1505 . G 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 17 1506 . G 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 17 1507 . A 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 17 1508 . C 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 17 1509 . A 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 17 1510 . G 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 17 1511 . A 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 17 1512 . A 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 17 1513 . G 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 17 1514 . G 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 17 1515 . G 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 17 1516 . T 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 17 1517 . C 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 17 1518 . C 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 17 1519 . T 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 17 1520 . G 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 17 1521 . C 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 17 1522 . G 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 17 1523 . T 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 17 1524 . G 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 17 1525 . C 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 17 1526 . C 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 17 1527 . C 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 17 1528 . T 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 17 1529 . G 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 17 1530 . C 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 17 1531 . C 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 17 1532 . T 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 17 1533 . T 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 17 1534 . C 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 17 1535 . A 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 17 1536 . C 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 17 1537 . A 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 17 1538 . A 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 17 1539 . G 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 17 1540 . C 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 17 1541 . C 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 17 1542 . C 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 17 1543 . C 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 17 1544 . T 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 17 1545 . G 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 17 1546 . G 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 17 1547 . A 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 17 1548 . A 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 17 1549 . G 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 17 1550 . G 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 17 1551 . A 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 17 1552 . A 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 17 1553 . A 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 17 1554 . G 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 17 1555 . T 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 17 1556 . T 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 17 1557 . G 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 17 1558 . T 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 17 1559 . T 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 17 1560 . T 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 17 1561 . T 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 17 1562 . G 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 17 1563 . G 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 17 1564 . G 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 17 1565 . A 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 17 1566 . T 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 17 1567 . C 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 17 1568 . T 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 17 1569 . C 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 17 1570 . T 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 17 1571 . G 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 17 1572 . C 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 17 1573 . A 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 17 1574 . C 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 17 1575 . C 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 17 1576 . C 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 17 1577 . T 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 17 1578 . C 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 17 1579 . A 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 17 1580 . G 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 17 1581 . C 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 17 1582 . C 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 17 1583 . T 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 17 1584 . G 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 17 1585 . G 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 17 1586 . A 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 17 1587 . C 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 17 1588 . A 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 17 1589 . A 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 17 1590 . C 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 17 1591 . T 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 17 1592 . T 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 17 1593 . G 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 17 1594 . T 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 17 1595 . G 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 17 1596 . C 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 17 1597 . C 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 17 1598 . C 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 17 1599 . A 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 17 1600 . T 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 17 1601 . C 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 17 1602 . T 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 17 1603 . G 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 17 1604 . G 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 17 1605 . T 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 17 1606 . G 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 17 1607 . A 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 17 1608 . C 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 17 1609 . C 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 17 1610 . C 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 17 1611 . C 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 17 1612 . T 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 17 1613 . C 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 17 1614 . A 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 17 1615 . C 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 17 1616 . T 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 17 1617 . C 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 17 1618 . A 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 17 1619 . G 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 17 1620 . C 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 17 1621 . C 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 17 1622 . A 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 17 1623 . C 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 17 1624 . C 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 17 1625 . A 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 17 1626 . G 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 17 1627 . A 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 17 1628 . C 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 17 1629 . T 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 17 1630 . T 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 17 1631 . C 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 17 1632 . C 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 17 1633 . A 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 17 1634 . C 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 17 1635 . G 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 17 1636 . A 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 17 1637 . C 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 17 1638 . A 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 17 1639 . G 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 17 1640 . G 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 17 1641 . C 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 17 1642 . T 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 17 1643 . C 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 17 1644 . C 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 17 1645 . A 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 17 1646 . G 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 17 1647 . C 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 17 1648 . C 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 17 1649 . T 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 17 1650 . C 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 17 1651 . G 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 17 1652 . G 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 17 1653 . C 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 17 1654 . A T, 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 17 1655 . C 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 17 1656 . C 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 17 1657 . T A, 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 17 1658 . T 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 17 1659 . C 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 17 1660 . A 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 17 1661 . G 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 17 1662 . C 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 17 1663 . C 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 17 1664 . A C, 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 17 1665 . T C, 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 17 1666 . G 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 17 1667 . G 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 17 1668 . A 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 17 1669 . C 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 17 1670 . A 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 17 1671 . G 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 17 1672 . T 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 17 1673 . T 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 17 1674 . C 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 17 1675 . C 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 17 1676 . G 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 17 1677 . C 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 17 1678 . C 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 17 1679 . A 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 17 1680 . G 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 17 1681 . C 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 17 1682 . G 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 17 1683 . T 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 17 1684 . T 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 17 1685 . G 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 17 1686 . C 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 17 1687 . C 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 17 1688 . C 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 17 1689 . T A, 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 17 1690 . C 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 17 1691 . T 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 17 1692 . G 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 17 1693 . T 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 17 1694 . T 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 17 1695 . C 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 17 1696 . T 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 17 1697 . G 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 17 1698 . C A, 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 17 1699 . T 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 17 1700 . G 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 17 1701 . T 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 17 1702 . T 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 17 1703 . T 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 17 1704 . T 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 17 1705 . C 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 17 1706 . T 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 17 1707 . C 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 17 1708 . T 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 17 1709 . A 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 17 1710 . C 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 17 1711 . C 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 17 1712 . A 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 17 1713 . G 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 17 1714 . A 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 17 1715 . A 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 17 1716 . G 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 17 1717 . T 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 17 1718 . G 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 17 1719 . C 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 17 1720 . C 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 17 1721 . C 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 17 1722 . T 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 17 1723 . T 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 17 1724 . C 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 17 1725 . C G, 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 17 1726 . C 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 17 1727 . T 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 17 1728 . C 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 17 1729 . C 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 17 1730 . T 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 17 1731 . C 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 17 1732 . A 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 17 1733 . C 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 17 1734 . C 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 17 1735 . T 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 17 1736 . G 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 17 1737 . A 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 17 1738 . C 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 17 1739 . C 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 17 1740 . A 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 17 1741 . C 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 17 1742 . T 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 17 1743 . C 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 17 1744 . T 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 17 1745 . G 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 17 1746 . G 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 17 1747 . G 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 17 1748 . G 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 17 1749 . A 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 17 1750 . A 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 17 1751 . A 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 17 1752 . T 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 17 1753 . C 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 17 1754 . C 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 17 1755 . C 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 17 1756 . T 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 17 1757 . C 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 17 1758 . A 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 17 1759 . G 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 17 1760 . C 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 17 1761 . A 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 17 1762 . C 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 17 1763 . C 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 17 1764 . C 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 17 1765 . T 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 17 1766 . C 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 17 1767 . C 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 17 1768 . C 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 17 1769 . T 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 17 1770 . G 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 17 1771 . A 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 17 1772 . G 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 17 1773 . C 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 17 1774 . A 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 17 1775 . T 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 17 1776 . A 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 17 1777 . C 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 17 1778 . C 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 17 1779 . C 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 17 1780 . T 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 17 1781 . A 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 17 1782 . C 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 17 1783 . T 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 17 1784 . C 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 17 1785 . T 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 17 1786 . G 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 17 1787 . G 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 17 1788 . C 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 17 1789 . A 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 17 1790 . C 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 17 1791 . A 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 17 1792 . A 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 17 1793 . G 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 17 1794 . C 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 17 1795 . C 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 17 1796 . C 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 17 1797 . A 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 17 1798 . C 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 17 1799 . C 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 17 1800 . C 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 17 1801 . T 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 17 1802 . G 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 17 1803 . C 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 17 1804 . A 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 17 1805 . A 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 17 1806 . A 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 17 1807 . G 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 17 1808 . C 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 17 1809 . C 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 17 1810 . C 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 17 1811 . C 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 17 1812 . T 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 17 1813 . G 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 17 1814 . A 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 17 1815 . G 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 17 1816 . G 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 17 1817 . C 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 17 1818 . C 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 17 1819 . C 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 17 1820 . G 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 17 1821 . C 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 17 1822 . C 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 17 1823 . C 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 17 1824 . T 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 17 1825 . G 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 17 1826 . T 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 17 1827 . G 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 17 1828 . G 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 17 1829 . C 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 17 1830 . G 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 17 1831 . T 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 17 1832 . C 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 17 1833 . T 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 17 1834 . C 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 17 1835 . T 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 17 1836 . C 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 17 1837 . C 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 17 1838 . C 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 17 1839 . T 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 17 1840 . C 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 17 1841 . C 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 17 1842 . C 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 17 1843 . T 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 17 1844 . T 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 17 1845 . G 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 17 1846 . C 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 17 1847 . T 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 17 1848 . G 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 17 1849 . T 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 17 1850 . C 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 17 1851 . A 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 17 1852 . G 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 17 1853 . G 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 17 1854 . A 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 17 1855 . C 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 17 1856 . A 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 17 1857 . G 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 17 1858 . T 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 17 1859 . G 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 17 1860 . G 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 17 1861 . T 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 17 1862 . C 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 17 1863 . C 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 17 1864 . T 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 17 1865 . G 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 17 1866 . G 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 17 1867 . C 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 17 1868 . C 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 17 1869 . A T, 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 17 1870 . C 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 17 1871 . C 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 17 1872 . G 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 17 1873 . G 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 17 1874 . G 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 17 1875 . G 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 17 1876 . C 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 17 1877 . T 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 17 1878 . C 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 17 1879 . A 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 17 1880 . C 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 17 1881 . G 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 17 1882 . G 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 17 1883 . A 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 17 1884 . G 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 17 1885 . C 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 17 1886 . C 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 17 1887 . G 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 17 1888 . C 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 17 1889 . C 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 17 1890 . C 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 17 1891 . T 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 17 1892 . G 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 17 1893 . T 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 17 1894 . G 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 17 1895 . C 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 17 1896 . C 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 17 1897 . G 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 17 1898 . T 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 17 1899 . G 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 17 1900 . T 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 17 1901 . A 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 17 1902 . C 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 17 1903 . C 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 17 1904 . T 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 17 1905 . C 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 17 1906 . T 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 17 1907 . G 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 17 1908 . A 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 17 1909 . G 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 17 1910 . C 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 17 1911 . C 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 17 1912 . C 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 17 1913 . T 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 17 1914 . C 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 17 1915 . T C, 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 17 1916 . G T, 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 17 1917 . C 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 17 1918 . A 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 17 1919 . C 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 17 1920 . A T, 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 17 1921 . G 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 17 1922 . T 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 17 1923 . G 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 17 1924 . C 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 17 1925 . C 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 17 1926 . T 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 17 1927 . T 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 17 1928 . C 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 17 1929 . T 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 17 1930 . G 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 17 1931 . C 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 17 1932 . T 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 17 1933 . T 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 17 1934 . G 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 17 1935 . C 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 17 1936 . C 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 17 1937 . T 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 17 1938 . G 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 17 1939 . T 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 17 1940 . G 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 17 1941 . G 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 17 1942 . C 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 17 1943 . T 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 17 1944 . T 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 17 1945 . T 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 17 1946 . G 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 17 1947 . A 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 17 1948 . G C, 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 17 1949 . A 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 17 1950 . A 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 17 1951 . G 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 17 1952 . A 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 17 1953 . A 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 17 1954 . A C, 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 17 1955 . C 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 17 1956 . C 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 17 1957 . C 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 17 1958 . C 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 17 1959 . T 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 17 1960 . T 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 17 1961 . C 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 17 1962 . T 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 17 1963 . G 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 17 1964 . G 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 17 1965 . T 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 17 1966 . T 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 17 1967 . A 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 17 1968 . T 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 17 1969 . A 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 17 1970 . C 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 17 1971 . A 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 17 1972 . T 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 17 1973 . A 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 17 1974 . A 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 17 1975 . G 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 17 1976 . A 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 17 1977 . C 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 17 1978 . A 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 17 1979 . G 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 17 1980 . C 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 17 1981 . C 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 17 1982 . A 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 17 1983 . G 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 17 1984 . A 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 17 1985 . G 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 17 1986 . A 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 17 1987 . A 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 17 1988 . G 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 17 1989 . G 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 17 1990 . G T, 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 17 1991 . A 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 17 1992 . G 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 17 1993 . T 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 17 1994 . T 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 17 1995 . G 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 17 1996 . C 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 17 1997 . C 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 17 1998 . C 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 17 1999 . A 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 17 2000 . G 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 17 2001 . G 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 17 2002 . G 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 17 2003 . T 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 17 2004 . G 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 17 2005 . G 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 17 2006 . C 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 17 2007 . A 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 17 2008 . C 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 17 2009 . A 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 17 2010 . G 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 17 2011 . C 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 17 2012 . A 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 17 2013 . C 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 17 2014 . G 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 17 2015 . T 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 17 2016 . T 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 17 2017 . G 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 17 2018 . C 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 17 2019 . T 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 17 2020 . G 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 17 2021 . C 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 17 2022 . C 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 17 2023 . A 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 17 2024 . G 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 17 2025 . T 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 17 2026 . T 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 17 2027 . A 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 17 2028 . C 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 17 2029 . T 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 17 2030 . G 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 17 2031 . C 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 17 2032 . C 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 17 2033 . A 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 17 2034 . T 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 17 2035 . T 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 17 2036 . T 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 17 2037 . T 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 17 2038 . C 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 17 2039 . A 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 17 2040 . C 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 17 2041 . G A, 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 17 2042 . G 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 17 2043 . G 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 17 2044 . C 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 17 2045 . A 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 17 2046 . T 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 17 2047 . G 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 17 2048 . A 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 17 2049 . A 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 17 2050 . A 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 17 2051 . T 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 17 2052 . G 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 17 2053 . G T, 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 17 2054 . A 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 17 2055 . G 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 17 2056 . A 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 17 2057 . T 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 17 2058 . A 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 17 2059 . A 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 17 2060 . C 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 17 2061 . A 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 17 2062 . A 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 17 2063 . C 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 17 2064 . A 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 17 2065 . G 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 17 2066 . G 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 17 2067 . A 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 17 2068 . G 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 17 2069 . C 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 17 2070 . G 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 17 2071 . A 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 17 2072 . C 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 17 2073 . C 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 17 2074 . G 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 17 2075 . C 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 17 2076 . A 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 17 2077 . C 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 17 2078 . A 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 17 2079 . G 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 17 2080 . G 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 17 2081 . C 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 17 2082 . T 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 17 2083 . G 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 17 2084 . C 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 17 2085 . T 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 17 2086 . G 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 17 2087 . A 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 17 2088 . G 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 17 2089 . C 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 17 2090 . G 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 17 2091 . C 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 17 2092 . G 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 17 2093 . T G, 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 17 2094 . C 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 17 2095 . A 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 17 2096 . C 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 17 2097 . A 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 17 2098 . C 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 17 2099 . G 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 17 2100 . C 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 17 2101 . A 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 17 2102 . G 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 17 2103 . C 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 17 2104 . C 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 17 2105 . A 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 17 2106 . T 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 17 2107 . C 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 17 2108 . G 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 17 2109 . C 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 17 2110 . G 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 17 2111 . C 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 17 2112 . A 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 17 2113 . G 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 17 2114 . C 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 17 2115 . T 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 17 2116 . C 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 17 2117 . A 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 17 2118 . G 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 17 2119 . G 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 17 2120 . G 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 17 2121 . A 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 17 2122 . T 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 17 2123 . A 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 17 2124 . T 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 17 2125 . T 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 17 2126 . A 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 17 2127 . C 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 17 2128 . G 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 17 2129 . T 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 17 2130 . G 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 17 2131 . T 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 17 2132 . A 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 17 2133 . A 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 17 2134 . C 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 17 2135 . T 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 17 2136 . C 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 17 2137 . G 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 17 2138 . A 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 17 2139 . C 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 17 2140 . A 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 17 2141 . T 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 17 2142 . G 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 17 2143 . T 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 17 2144 . C 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 17 2145 . A 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 17 2146 . G 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 17 2147 . C 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 17 2148 . G 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 17 2149 . A 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 17 2150 . T 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 17 2151 . T 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 17 2152 . G 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 17 2153 . T 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 17 2154 . C 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 17 2155 . A 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 17 2156 . C 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 17 2157 . A 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 17 2158 . G 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 17 2159 . G 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 17 2160 . C 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 17 2161 . A 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 17 2162 . C 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 17 2163 . T 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 17 2164 . G 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 17 2165 . C 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 17 2166 . T 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 17 2167 . A 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 17 2168 . C 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 17 2169 . T 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 17 2170 . C 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 17 2171 . C 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 17 2172 . T 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 17 2173 . G 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 17 2174 . G 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 17 2175 . G 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 17 2176 . G 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 17 2177 . T 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 17 2178 . T 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 17 2179 . T 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 17 2180 . T 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 17 2181 . C 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 17 2182 . C 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 17 2183 . A 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 17 2184 . T 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 17 2185 . C 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 17 2186 . A 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 17 2187 . A 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 17 2188 . A 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 17 2189 . C 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 17 2190 . C 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 17 2191 . C 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 17 2192 . T 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 17 2193 . C 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 17 2194 . A 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 17 2195 . A 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 17 2196 . G 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 17 2197 . A 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 17 2198 . G 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 17 2199 . C 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 17 2200 . T 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 17 2201 . G 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 17 2202 . G 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 17 2203 . G 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 17 2204 . C 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 17 2205 . C 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 17 2206 . T 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 17 2207 . G 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 17 2208 . G 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 17 2209 . G 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 17 2210 . G C, 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 17 2211 . T 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 17 2212 . C 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 17 2213 . A 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 17 2214 . A 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 17 2215 . C 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 17 2216 . T 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 17 2217 . T 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 17 2218 . C 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 17 2219 . C 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 17 2220 . G A, 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 17 2221 . G 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 17 2222 . C 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 17 2223 . C 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 17 2224 . T 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 17 2225 . G 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 17 2226 . G 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 17 2227 . G 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 17 2228 . G C, 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 17 2229 . A 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 17 2230 . A 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 17 2231 . A 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 17 2232 . C 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 17 2233 . T 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 17 2234 . G 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 17 2235 . G 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 17 2236 . G 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 17 2237 . G 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 17 2238 . C 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 17 2239 . A 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 17 2240 . A 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 17 2241 . G 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 17 2242 . T 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 17 2243 . A 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 17 2244 . T 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 17 2245 . C 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 17 2246 . A 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 17 2247 . C 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 17 2248 . C 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 17 2249 . A 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 17 2250 . G 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 17 2251 . A 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 17 2252 . G 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 17 2253 . A 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 17 2254 . T 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 17 2255 . G 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 17 2256 . A 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 17 2257 . G 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 17 2258 . C 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 17 2259 . T 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 17 2260 . T 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 17 2261 . T 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 17 2262 . A 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 17 2263 . T 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 17 2264 . A 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 17 2265 . A 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 17 2266 . A 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 17 2267 . A 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 17 2268 . A 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 17 2269 . T 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 17 2270 . A 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 17 2271 . A 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 17 2272 . T 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 17 2273 . G 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 17 2274 . G 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 17 2275 . T 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 17 2276 . G 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 17 2277 . C 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 17 2278 . T 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 17 2279 . A 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 17 2280 . G 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 17 2281 . C 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 17 2282 . T 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 17 2283 . G 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 17 2284 . G 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 17 2285 . G 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 17 2286 . C 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 17 2287 . A 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 17 2288 . T 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 17 2289 . G 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 17 2290 . G 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 17 2291 . T 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 17 2292 . G 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 17 2293 . G 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 17 2294 . C 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 17 2295 . T 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 17 2296 . T 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 17 2297 . G 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 17 2298 . C 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 17 2299 . A 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 17 2300 . C 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 17 2301 . C 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 17 2302 . T 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 17 2303 . G 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 17 2304 . T 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 17 2305 . A 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 17 2306 . A 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 17 2307 . T 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 17 2308 . C 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 17 2309 . C A, 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 17 2310 . C 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 17 2311 . A 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 17 2312 . G 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 17 2313 . C 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 17 2314 . A 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 17 2315 . C 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 17 2316 . T 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 17 2317 . T 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 17 2318 . T 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 17 2319 . G 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 17 2320 . G 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 17 2321 . G 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 17 2322 . A 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 17 2323 . G 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 17 2324 . G 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 17 2325 . C 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 17 2326 . C 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 17 2327 . G 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 17 2328 . A 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 17 2329 . G 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 17 2330 . C 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 17 2331 . T 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 17 2332 . A 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 17 2333 . G 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 17 2334 . G 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 17 2335 . A 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 17 2336 . G 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 17 2337 . G 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 17 2338 . A 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 17 2339 . T 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 17 2340 . C 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 17 2341 . G 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 17 2342 . T 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 17 2343 . T 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 17 2344 . T 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 17 2345 . G 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 17 2346 . A 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 17 2347 . G 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 17 2348 . T 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 17 2349 . C 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 17 2350 . C 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 17 2351 . A 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 17 2352 . G 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 17 2353 . C 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 17 2354 . A 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 17 2355 . G 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 17 2356 . T 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 17 2357 . T 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 17 2358 . T 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 17 2359 . G 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 17 2360 . A 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 17 2361 . G 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 17 2362 . A 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 17 2363 . C 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 17 2364 . C 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 17 2365 . A 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 17 2366 . G 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 17 2367 . C 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 17 2368 . C 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 17 2369 . T 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 17 2370 . G 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 17 2371 . G 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 17 2372 . C 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 17 2373 . C 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 17 2374 . A 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 17 2375 . A 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 17 2376 . T 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 17 2377 . A 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 17 2378 . C 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 17 2379 . G 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 17 2380 . G 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 17 2381 . C 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 17 2382 . A 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 17 2383 . A 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 17 2384 . A 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 17 2385 . A 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 17 2386 . C 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 17 2387 . C 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 17 2388 . C 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 17 2389 . A 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 17 2390 . G 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 17 2391 . T 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 17 2392 . C 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 17 2393 . T 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 17 2394 . C 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 17 2395 . T 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 17 2396 . A 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 17 2397 . C 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 17 2398 . A 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 17 2399 . A 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 17 2400 . A 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 17 2401 . A 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 17 2402 . A 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 17 2403 . A 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 17 2404 . T 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 17 2405 . A 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 17 2406 . C 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 17 2407 . A 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 17 2408 . A 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 17 2409 . A 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 17 2410 . A 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 17 2411 . A 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 17 2412 . A 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 17 2413 . C 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 17 2414 . A 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 17 2415 . A 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 17 2416 . C 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 17 2417 . T 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 17 2418 . A 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 17 2419 . G 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 17 2420 . C 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 17 2421 . C 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 17 2422 . A 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 17 2423 . G 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 17 2424 . G 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 17 2425 . C 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 17 2426 . G 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 17 2427 . T 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 17 2428 . G 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 17 2429 . G 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 17 2430 . T A, 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 17 2431 . G 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 17 2432 . G 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 17 2433 . T 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 17 2434 . G 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 17 2435 . C 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 17 2436 . A 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 17 2437 . C 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 17 2438 . A 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 17 2439 . C 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 17 2440 . C 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 17 2441 . T 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 17 2442 . G 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 17 2443 . T 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 17 2444 . A 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 17 2445 . G 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 17 2446 . T 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 17 2447 . C 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 17 2448 . C 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 17 2449 . C 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 17 2450 . A 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 17 2451 . G 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 17 2452 . C 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 17 2453 . T 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 17 2454 . A 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 17 2455 . C 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 17 2456 . T 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 17 2457 . C 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 17 2458 . A 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 17 2459 . G T, 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 17 2460 . G 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 17 2461 . A G, 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 17 2462 . G 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 17 2463 . G T, 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 17 2464 . C 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 17 2465 . T 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 17 2466 . G 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 17 2467 . A 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 17 2468 . G 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 17 2469 . G 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 17 2470 . G 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 17 2471 . G 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 17 2472 . G 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 17 2473 . A 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 17 2474 . A 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 17 2475 . G 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 17 2476 . G 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 17 2477 . A 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 17 2478 . C 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 17 2479 . T 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 17 2480 . G 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 17 2481 . C 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 17 2482 . T 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 17 2483 . T 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 17 2484 . G 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 17 2485 . A T, 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 17 2486 . G 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 17 2487 . C 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 17 2488 . C 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 17 2489 . C 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 17 2490 . A 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 17 2491 . G 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 17 2492 . G A, 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 17 2493 . A G, 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 17 2494 . G 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 17 2495 . T 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 17 2496 . T 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 17 2497 . T 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 17 2498 . G 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 17 2499 . A 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 17 2500 . G 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 17 2501 . G 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 17 2502 . C 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 17 2503 . T 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 17 2504 . G 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 17 2505 . C 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 17 2506 . T 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 17 2507 . G 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 17 2508 . T 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 17 2509 . G T, 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 17 2510 . A 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 17 2511 . G 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 17 2512 . C 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 17 2513 . T 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 17 2514 . G 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 17 2515 . T 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 17 2516 . G 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 17 2517 . A 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 17 2518 . T 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 17 2519 . C 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 17 2520 . G 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 17 2521 . C 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 17 2522 . A 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 17 2523 . T 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 17 2524 . C 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 17 2525 . A C, 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 17 2526 . C 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 17 2527 . T 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 17 2528 . G 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 17 2529 . C 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 17 2530 . A 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 17 2531 . T 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 17 2532 . T 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 17 2533 . C 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 17 2534 . C 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 17 2535 . A 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 17 2536 . G 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 17 2537 . C 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 17 2538 . C 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 17 2539 . C 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 17 2540 . G 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 17 2541 . G 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 17 2542 . T 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 17 2543 . G 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 17 2544 . A 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 17 2545 . C 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 17 2546 . A 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 17 2547 . G 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 17 2548 . A 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 17 2549 . G 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 17 2550 . T 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 17 2551 . G 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 17 2552 . A 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 17 2553 . G 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 17 2554 . T 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 17 2555 . C 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 17 2556 . A 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 17 2557 . C 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 17 2558 . T 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 17 2559 . G 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 17 2560 . T 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 17 2561 . C 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 17 2562 . T 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 17 2563 . C 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 17 2564 . A G, 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 17 2565 . A 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 17 2566 . A 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 17 2567 . A 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 17 2568 . A 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 17 2569 . A 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 17 2570 . G 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 17 2571 . A 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 17 2572 . A 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 17 2573 . A 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 17 2574 . G 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 17 2575 . G 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 17 2576 . A 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 17 2577 . A 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 17 2578 . G 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 17 2579 . A 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 17 2580 . A 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 17 2581 . A 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 17 2582 . T 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 17 2583 . A 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 17 2584 . A 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 17 2585 . A 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 17 2586 . G 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 17 2587 . A 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 17 2588 . A 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 17 2589 . A 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 17 2590 . A 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 17 2591 . C 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 17 2592 . A 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 17 2593 . A 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 17 2594 . A 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 17 2595 . T 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 17 2596 . A 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 17 2597 . A 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 17 2598 . A 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 17 2599 . A 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 17 2600 . A 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 17 2601 . T 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 17 2602 . A 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 17 2603 . A 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 17 2604 . T 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 17 2605 . A 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 17 2606 . G 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 17 2607 . T 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 17 2608 . G 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 17 2609 . C 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 17 2610 . A 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 17 2611 . G 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 17 2612 . A 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 17 2613 . C 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 17 2614 . A 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 17 2615 . A 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 17 2616 . A 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 17 2617 . A 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 17 2618 . G 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 17 2619 . G 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 17 2620 . C 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 17 2621 . C 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 17 2622 . T 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 17 2623 . T 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 17 2624 . G 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 17 2625 . A 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 17 2626 . C 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 17 2627 . C 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 17 2628 . C 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 17 2629 . A 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 17 2630 . T 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 17 2631 . C 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 17 2632 . T 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 17 2633 . A 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 17 2634 . G 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 17 2635 . C 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 17 2636 . T 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 17 2637 . T 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 17 2638 . T 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 17 2639 . G 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 17 2640 . G 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 17 2641 . C 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 17 2642 . C 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 17 2643 . C 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 17 2644 . T 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 17 2645 . C 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 17 2646 . A 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 17 2647 . G 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 17 2648 . C 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 17 2649 . A 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 17 2650 . T 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 17 2651 . C 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 17 2652 . A 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 17 2653 . A 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 17 2654 . C 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 17 2655 . C 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 17 2656 . G 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 17 2657 . C 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 17 2658 . T 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 17 2659 . A 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 17 2660 . G 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 17 2661 . A 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 17 2662 . T 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 17 2663 . A 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 17 2664 . C 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 17 2665 . G 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 17 2666 . T 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 17 2667 . C 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 17 2668 . C 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 17 2669 . C 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 17 2670 . T 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 17 2671 . C 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 17 2672 . C 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 17 2673 . C 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 17 2674 . T 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 17 2675 . T 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 17 2676 . T 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 17 2677 . C 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 17 2678 . T 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 17 2679 . T 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 17 2680 . C 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 17 2681 . T 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 17 2682 . G 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 17 2683 . G 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 17 2684 . G 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 17 2685 . G 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 17 2686 . C 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 17 2687 . A 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 17 2688 . C 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 17 2689 . A 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 17 2690 . G 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 17 2691 . G 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 17 2692 . T 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 17 2693 . C 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 17 2694 . A 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 17 2695 . C 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 17 2696 . A 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 17 2697 . C 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 17 2698 . T 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 17 2699 . C 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 17 2700 . T 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 17 2701 . C 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 17 2702 . T 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 17 2703 . T 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 17 2704 . C 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 17 2705 . C 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 17 2706 . A 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 17 2707 . G 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 17 2708 . G 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 17 2709 . T 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 17 2710 . C 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 17 2711 . T 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 17 2712 . A 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 17 2713 . G T, 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 17 2714 . G 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 17 2715 . A 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 17 2716 . T 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 17 2717 . G 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 17 2718 . C 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 17 2719 . A 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 17 2720 . G 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 17 2721 . C 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 17 2722 . T 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 17 2723 . G 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 17 2724 . A 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 17 2725 . G 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 17 2726 . G 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 17 2727 . G 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 17 2728 . G 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 17 2729 . T 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 17 2730 . G 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 17 2731 . C 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 17 2732 . C 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 17 2733 . C A, 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 17 2734 . C 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 17 2735 . T 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 17 2736 . C 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 17 2737 . T 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 17 2738 . T 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 17 2739 . A 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 17 2740 . C 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 17 2741 . C 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 17 2742 . A 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 17 2743 . T 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 17 2744 . C 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 17 2745 . T 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 17 2746 . A 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 17 2747 . A 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 17 2748 . T 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 17 2749 . C 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 17 2750 . T 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 17 2751 . G 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 17 2752 . T 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 17 2753 . G 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 17 2754 . C 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 17 2755 . C 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 17 2756 . C 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 17 2757 . T 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 17 2758 . T 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 17 2759 . A 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 17 2760 . T 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 17 2761 . T 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 17 2762 . T 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 17 2763 . C A, 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 17 2764 . C 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 17 2765 . T 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 17 2766 . C 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 17 2767 . T 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 17 2768 . G 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 17 2769 . C 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 17 2770 . T 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 17 2771 . T 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 17 2772 . T 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 17 2773 . A 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 17 2774 . G 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 17 2775 . T 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 17 2776 . G 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 17 2777 . A 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 17 2778 . G 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 17 2779 . G 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 17 2780 . A 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 17 2781 . A 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 17 2782 . G 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 17 2783 . A 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 17 2784 . G 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 17 2785 . G 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 17 2786 . C 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 17 2787 . C 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 17 2788 . C 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 17 2789 . C 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 17 2790 . T 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 17 2791 . G 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 17 2792 . G 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 17 2793 . T 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 17 2794 . C 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 17 2795 . C 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 17 2796 . A 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 17 2797 . T 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 17 2798 . G 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 17 2799 . A 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 17 2800 . A 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 17 2801 . G 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 17 2802 . G 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 17 2803 . G 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 17 2804 . G 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 17 2805 . C 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 17 2806 . C 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 17 2807 . T 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 17 2808 . T 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 17 2809 . T 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 17 2810 . C 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 17 2811 . A 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 17 2812 . G 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 17 2813 . A 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 17 2814 . G 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 17 2815 . A 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 17 2816 . C 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 17 2817 . G 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 17 2818 . G 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 17 2819 . G 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 17 2820 . G 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 17 2821 . A 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 17 2822 . C 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 17 2823 . C 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 17 2824 . C 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 17 2825 . C 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 17 2826 . T 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 17 2827 . G 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 17 2828 . A 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 17 2829 . G 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 17 2830 . G 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 17 2831 . A 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 17 2832 . G 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 17 2833 . C 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 17 2834 . C 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 17 2835 . C 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 17 2836 . C 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 17 2837 . G 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 17 2838 . A 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 17 2839 . G 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 17 2840 . C 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 17 2841 . A 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 17 2842 . G 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 17 2843 . C 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 17 2844 . A 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 17 2845 . G 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 17 2846 . C 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 17 2847 . C 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 17 2848 . G 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 17 2849 . T 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 17 2850 . C 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 17 2851 . G 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 17 2852 . T 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 17 2853 . G 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 17 2854 . T 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 17 2855 . C 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 17 2856 . T 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 17 2857 . C 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 17 2858 . A 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 17 2859 . C 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 17 2860 . C 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 17 2861 . C 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 17 2862 . A 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 17 2863 . G 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 17 2864 . G 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 17 2865 . G 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 17 2866 . T 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 17 2867 . G 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 17 2868 . T 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 17 2869 . C 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 17 2870 . T 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 17 2871 . G 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 17 2872 . A 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 17 2873 . A 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 17 2874 . A 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 17 2875 . C 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 17 2876 . A 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 17 2877 . G 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 17 2878 . A 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 17 2879 . T 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 17 2880 . G 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 17 2881 . T 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 17 2882 . G 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 17 2883 . G 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 17 2884 . A 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 17 2885 . G 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 17 2886 . G A, 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 17 2887 . T 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 17 2888 . C 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 17 2889 . T 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 17 2890 . C 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 17 2891 . G 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 17 2892 . G 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 17 2893 . G 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 17 2894 . T 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 17 2895 . G 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 17 2896 . A 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 17 2897 . G 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 17 2898 . G 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 17 2899 . C 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 17 2900 . G 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 17 2901 . T 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 17 2902 . G 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 17 2903 . G 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 17 2904 . C 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 17 2905 . T 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 17 2906 . C 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 17 2907 . A 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 17 2908 . G 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 17 2909 . A 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 17 2910 . T 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 17 2911 . A 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 17 2912 . C 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 17 2913 . A 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 17 2914 . G 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 17 2915 . G 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 17 2916 . G 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 17 2917 . A 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 17 2918 . G 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 17 2919 . T 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 17 2920 . G 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 17 2921 . G 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 17 2922 . C 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 17 2923 . C 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 17 2924 . C 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 17 2925 . A 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 17 2926 . C 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 17 2927 . A 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 17 2928 . G 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 17 2929 . C 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 17 2930 . T 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 17 2931 . C 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 17 2932 . G 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 17 2933 . G 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 17 2934 . C 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 17 2935 . C 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 17 2936 . T 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 17 2937 . G 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 17 2938 . T 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 17 2939 . C 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 17 2940 . T 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 17 2941 . T 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 17 2942 . T 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 17 2943 . G 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 17 2944 . A 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 17 2945 . A 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 17 2946 . A 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 17 2947 . G 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 17 2948 . G 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 17 2949 . C 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 17 2950 . C 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 17 2951 . A 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 17 2952 . C 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 17 2953 . G 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 17 2954 . T 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 17 2955 . G 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 17 2956 . A 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 17 2957 . C 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 17 2958 . C 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 17 2959 . T 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 17 2960 . G 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 17 2961 . G 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 17 2962 . C 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 17 2963 . C 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 17 2964 . C 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 17 2965 . A 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 17 2966 . C 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 17 2967 . G 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 17 2968 . G 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 17 2969 . C 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 17 2970 . T 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 17 2971 . G 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 17 2972 . G 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 17 2973 . C 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 17 2974 . A 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 17 2975 . G 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 17 2976 . G 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 17 2977 . T 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 17 2978 . G 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 17 2979 . G 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 17 2980 . G 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 17 2981 . A 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 17 2982 . C 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 17 2983 . C 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 17 2984 . C 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 17 2985 . A 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 17 2986 . G 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 17 2987 . C 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 17 2988 . T 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 17 2989 . G 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 17 2990 . C 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 17 2991 . A 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 17 2992 . G 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 17 2993 . G 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 17 2994 . G 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 17 2995 . G 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 17 2996 . T 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 17 2997 . C 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 17 2998 . C 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 17 2999 . A 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 17 3000 . G 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 17 3001 . C 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 17 3002 . A 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 17 3003 . G 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 17 3004 . C 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 17 3005 . A 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 17 3006 . C 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 17 3007 . C 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 17 3008 . C 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 17 3009 . A 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 17 3010 . C 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 17 3011 . A 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 17 3012 . G 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 17 3013 . C 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 17 3014 . A 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 17 3015 . G 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 17 3016 . C 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 17 3017 . C A, 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 17 3018 . A 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 17 3019 . C 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 17 3020 . C 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 17 3021 . T 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 17 3022 . G 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 17 3023 . T G, 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 17 3024 . G 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 17 3025 . G 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 17 3026 . C 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 17 3027 . A 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 17 3028 . G 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 17 3029 . G 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 17 3030 . G 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 17 3031 . A 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 17 3032 . G 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 17 3033 . G 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 17 3034 . A 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 17 3035 . G 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 17 3036 . C 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 17 3037 . T 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 17 3038 . T 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 17 3039 . G 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 17 3040 . T 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 17 3041 . G 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 17 3042 . G 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 17 3043 . T 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 17 3044 . A C, 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 17 3045 . C 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 17 3046 . A 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 17 3047 . G 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 17 3048 . T 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 17 3049 . G 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 17 3050 . G 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 17 3051 . A 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 17 3052 . C 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 17 3053 . A 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 17 3054 . G 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 17 3055 . G 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 17 3056 . C 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 17 3057 . C 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 17 3058 . C 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 17 3059 . T G, 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 17 3060 . G 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 17 3061 . C 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 17 3062 . C 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 17 3063 . C 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 17 3064 . A 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 17 3065 . G 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 17 3066 . A 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 17 3067 . T 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 17 3068 . G 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 17 3069 . G 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 17 3070 . C 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 17 3071 . C 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 17 3072 . C 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 17 3073 . C 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 17 3074 . C 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 17 3075 . C 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 17 3076 . G 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 17 3077 . C 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 17 3078 . C 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 17 3079 . T 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 17 3080 . G 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 17 3081 . C 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 17 3082 . C 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 17 3083 . T C, 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 17 3084 . G 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 17 3085 . T 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 17 3086 . G 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 17 3087 . G 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 17 3088 . A 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 17 3089 . A 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 17 3090 . G 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 17 3091 . T 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 17 3092 . T 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 17 3093 . G 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 17 3094 . A 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 17 3095 . C 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 17 3096 . C 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 17 3097 . A 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 17 3098 . G 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 17 3099 . A 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 17 3100 . C 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 17 3101 . C 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 17 3102 . A 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 17 3103 . T 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 17 3104 . C T, 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 17 3105 . T 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 17 3106 . G 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 17 3107 . T 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 17 3108 . C 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 17 3109 . A 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 17 3110 . C 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 17 3111 . A 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 17 3112 . G 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 17 3113 . C 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 17 3114 . A 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 17 3115 . G 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 17 3116 . G 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 17 3117 . T 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 17 3118 . A 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 17 3119 . A 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 17 3120 . G 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 17 3121 . A 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 17 3122 . C 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 17 3123 . T 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 17 3124 . C 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 17 3125 . T 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 17 3126 . G 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 17 3127 . C 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 17 3128 . T 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 17 3129 . T 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 17 3130 . T 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 17 3131 . C 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 17 3132 . T 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 17 3133 . G 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 17 3134 . G 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 17 3135 . G 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 17 3136 . C 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 17 3137 . A 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 17 3138 . A 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 17 3139 . C 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 17 3140 . C 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 17 3141 . C 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 17 3142 . A 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 17 3143 . G 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 17 3144 . C 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 17 3145 . A 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 17 3146 . G 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 17 3147 . G 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 17 3148 . T 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 17 3149 . G 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 17 3150 . A 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 17 3151 . C 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 17 3152 . C 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 17 3153 . C 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 17 3154 . T 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 17 3155 . G 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 17 3156 . G 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 17 3157 . A 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 17 3158 . A 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 17 3159 . T 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 17 3160 . T 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 17 3161 . C 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 17 3162 . C 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 17 3163 . T A, 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 17 3164 . G 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 17 3165 . T 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 17 3166 . C 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 17 3167 . C 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 17 3168 . A 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 17 3169 . T 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 17 3170 . C 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 17 3171 . T 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 17 3172 . G 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 17 3173 . G 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 17 3174 . C 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 17 3175 . A 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 17 3176 . G 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 17 3177 . G 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 17 3178 . T 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 17 3179 . G 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 17 3180 . G 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 17 3181 . G 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 17 3182 . C 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 17 3183 . A 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 17 3184 . T 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 17 3185 . T 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 17 3186 . G 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 17 3187 . A 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 17 3188 . A 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 17 3189 . A 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 17 3190 . C 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 17 3191 . T 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 17 3192 . G 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 17 3193 . G 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 17 3194 . T C, 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 17 3195 . T 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 17 3196 . T 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 17 3197 . A 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 17 3198 . A 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 17 3199 . A 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 17 3200 . A 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 17 3201 . A 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 17 3202 . T 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 17 3203 . G A, 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 17 3204 . T 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 17 3205 . C 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 17 3206 . A 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 17 3207 . C 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 17 3208 . A 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 17 3209 . C 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 17 3210 . C 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 17 3211 . A 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 17 3212 . T 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 17 3213 . A 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 17 3214 . G 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 17 3215 . G 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 17 3216 . C 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 17 3217 . C 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 17 3218 . G C, 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 17 3219 . G A, 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 17 3220 . G 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 17 3221 . C 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 17 3222 . A 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 17 3223 . C 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 17 3224 . A 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 17 3225 . G 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 17 3226 . T 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 17 3227 . G 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 17 3228 . G 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 17 3229 . C 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 17 3230 . T 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 17 3231 . C 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 17 3232 . A 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 17 3233 . C 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 17 3234 . G T, 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 17 3235 . C 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 17 3236 . C 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 17 3237 . T 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 17 3238 . G 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 17 3239 . T 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 17 3240 . A 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 17 3241 . A 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 17 3242 . T 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 17 3243 . C 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 17 3244 . C 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 17 3245 . C 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 17 3246 . A 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 17 3247 . G 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 17 3248 . C 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 17 3249 . C 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 17 3250 . C 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 17 3251 . T 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 17 3252 . T 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 17 3253 . T 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 17 3254 . G 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 17 3255 . G 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 17 3256 . G 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 17 3257 . A 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 17 3258 . G 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 17 3259 . G 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 17 3260 . C 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 17 3261 . C 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 17 3262 . A 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 17 3263 . G 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 17 3264 . G 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 17 3265 . G 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 17 3266 . T 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 17 3267 . G 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 17 3268 . G 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 17 3269 . G 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 17 3270 . T 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 17 3271 . G 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 17 3272 . G 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 17 3273 . A 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 17 3274 . T 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 17 3275 . C 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 17 3276 . A 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 17 3277 . C 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 17 3278 . T 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 17 3279 . T 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 17 3280 . G 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 17 3281 . A 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 17 3282 . G 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 17 3283 . G 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 17 3284 . T 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 17 3285 . C 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 17 3286 . A 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 17 3287 . G 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 17 3288 . G 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 17 3289 . A 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 17 3290 . G 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 17 3291 . T 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 17 3292 . T 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 17 3293 . C 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 17 3294 . A 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 17 3295 . A 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 17 3296 . G 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 17 3297 . A 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 17 3298 . C 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 17 3299 . C 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 17 3300 . A 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 17 3301 . G 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 17 3302 . C 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 17 3303 . C 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 17 3304 . T 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 17 3305 . G 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 17 3306 . G 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 17 3307 . C 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 17 3308 . C 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 17 3309 . A 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 17 3310 . A 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 17 3311 . C 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 17 3312 . A 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 17 3313 . T 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 17 3314 . G 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 17 3315 . G 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 17 3316 . T 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 17 3317 . G 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 17 3318 . A 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 17 3319 . A 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 17 3320 . A 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 17 3321 . C 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 17 3322 . C 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 17 3323 . C 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 17 3324 . C 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 17 3325 . G 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 17 3326 . T 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 17 3327 . C 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 17 3328 . T 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 17 3329 . A 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 17 3330 . C 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 17 3331 . T 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 17 3332 . A 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 17 3333 . A 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 17 3334 . A 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 17 3335 . A 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 17 3336 . A 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 17 3337 . T 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 17 3338 . A 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 17 3339 . C 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 17 3340 . A 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 17 3341 . A 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 17 3342 . A 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 17 3343 . A 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 17 3344 . A 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 17 3345 . T 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 17 3346 . T 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 17 3347 . A 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 17 3348 . G 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 17 3349 . C 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 17 3350 . C 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 17 3351 . T 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 17 3352 . G 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 17 3353 . G 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 17 3354 . C 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 17 3355 . G 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 17 3356 . T 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 17 3357 . G 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 17 3358 . G 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 17 3359 . T 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 17 3360 . G 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 17 3361 . G 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 17 3362 . C 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 17 3363 . G 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 17 3364 . C 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 17 3365 . A 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 17 3366 . T 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 17 3367 . G 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 17 3368 . C 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 17 3369 . C 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 17 3370 . T 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 17 3371 . G 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 17 3372 . T 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 17 3373 . A 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 17 3374 . A 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 17 3375 . T 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 17 3376 . C 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 17 3377 . C 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 17 3378 . C 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 17 3379 . A 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 17 3380 . G 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 17 3381 . C 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 17 3382 . T 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 17 3383 . A 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 17 3384 . C 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 17 3385 . T 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 17 3386 . T 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 17 3387 . G 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 17 3388 . G 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 17 3389 . G 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 17 3390 . A 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 17 3391 . A 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 17 3392 . G 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 17 3393 . C 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 17 3394 . T 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 17 3395 . G 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 17 3396 . A 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 17 3397 . G 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 17 3398 . G 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 17 3399 . G 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 17 3400 . A 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 17 3401 . T 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 17 3402 . G 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 17 3403 . A 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 17 3404 . G 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 17 3405 . A 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 17 3406 . A 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 17 3407 . C 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 17 3408 . T 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 17 3409 . G 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 17 3410 . C 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 17 3411 . T 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 17 3412 . T 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 17 3413 . G 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 17 3414 . A 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 17 3415 . A 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 17 3416 . C 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 17 3417 . C 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 17 3418 . T 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 17 3419 . G 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 17 3420 . G 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 17 3421 . G 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 17 3422 . A 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 17 3423 . G 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 17 3424 . G 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 17 3425 . C 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 17 3426 . A 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 17 3427 . G 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 17 3428 . A 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 17 3429 . C 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 17 3430 . G 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 17 3431 . T 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 17 3432 . T 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 17 3433 . G 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 17 3434 . C 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 17 3435 . A 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 17 3436 . G 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 17 3437 . T G, 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 17 3438 . G 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 17 3439 . A 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 17 3440 . G 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 17 3441 . C 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 17 3442 . T 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 17 3443 . G 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 17 3444 . A 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 17 3445 . G 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 17 3446 . A 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 17 3447 . T 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 17 3448 . C 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 17 3449 . A 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 17 3450 . C 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 17 3451 . G 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 17 3452 . C 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 17 3453 . C 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 17 3454 . A 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 17 3455 . C 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 17 3456 . T 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 17 3457 . G 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 17 3458 . C 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 17 3459 . A C, 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 17 3460 . C 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 17 3461 . T 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 17 3462 . C 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 17 3463 . C 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 17 3464 . A 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 17 3465 . G 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 17 3466 . C 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 17 3467 . C 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 17 3468 . T 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 17 3469 . G 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 17 3470 . G 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 17 3471 . G 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 17 3472 . C 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 17 3473 . A 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 17 3474 . A 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 17 3475 . C 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 17 3476 . A 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 17 3477 . G 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 17 3478 . A 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 17 3479 . G 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 17 3480 . T 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 17 3481 . A 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 17 3482 . A 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 17 3483 . G 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 17 3484 . A C, 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 17 3485 . C 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 17 3486 . T 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 17 3487 . C 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 17 3488 . T 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 17 3489 . G 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 17 3490 . T C, 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 17 3491 . C 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 17 3492 . T 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 17 3493 . C 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 17 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 17 3494 . A 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 17 3495 . A 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 17 3496 . A 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 17 3497 . A 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 17 3498 . A 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 17 3499 . A 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 17 3500 . A 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 17 3501 . A 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 17 3502 . A 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 17 3503 . A 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 17 3504 . A 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 17 3505 . A 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 17 3506 . A 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 17 3507 . T 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 17 3508 . C 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 17 3509 . A 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 17 3510 . C A, 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 17 3511 . A 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 17 3512 . C 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 17 3513 . C A, 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 17 3514 . A 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 17 3515 . T 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 17 3516 . T 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 17 3517 . T 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 17 3518 . T 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 17 3519 . G 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 17 3520 . G 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 17 3521 . C 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 17 3522 . T 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 17 3523 . T 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 17 3524 . C 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 17 3525 . A 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 17 3526 . G 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 17 3527 . A 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 17 3528 . T 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 17 3529 . T 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 17 3530 . G 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 17 3531 . C A, 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 17 3532 . A 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 17 3533 . T 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 17 3534 . A 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 17 3535 . T 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 17 3536 . C 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 17 3537 . C 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 17 3538 . T 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 17 3539 . C 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 17 3540 . C 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 17 3541 . T 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 17 3542 . G 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 17 3543 . C 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 17 3544 . A 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 17 3545 . A 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 17 3546 . G 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 17 3547 . G 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 17 3548 . A 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 17 3549 . T 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 17 3550 . A 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 17 3551 . T 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 17 3552 . A 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 17 3553 . T A, 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 17 3554 . A 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 17 3555 . C 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 17 3556 . G 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 17 3557 . C 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 17 3558 . G 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 17 3559 . T 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 17 3560 . G 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 17 3561 . A 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 17 3562 . A 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 17 3563 . A 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 17 3564 . T 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 17 3565 . T 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 17 3566 . C 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 17 3567 . A 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 17 3568 . A 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 17 3569 . G 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 17 3570 . T 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 17 3571 . C 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 17 3572 . A 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 17 3573 . A 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 17 3574 . T 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 17 3575 . G 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 17 3576 . A 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 17 3577 . C 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 17 3578 . A 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 17 3579 . A 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 17 3580 . A 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 17 3581 . T 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 17 3582 . C 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 17 3583 . A 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 17 3584 . G 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 17 3585 . A 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 17 3586 . A 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 17 3587 . G A, 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 17 3588 . A 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 17 3589 . A 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 17 3590 . A 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 17 3591 . A 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 17 3592 . A 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 17 3593 . A 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 17 3594 . C 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 17 3595 . A 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 17 3596 . T 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 17 3597 . A 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 17 3598 . T 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 17 3599 . A 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 17 3600 . T 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 17 3601 . A 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 17 3602 . T 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 17 3603 . A 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 17 3604 . C 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 17 3605 . G 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 17 3606 . C 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 17 3607 . A 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 17 3608 . A 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 17 3609 . A 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 17 3610 . C 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 17 3611 . C 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 17 3612 . A 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 17 3613 . G 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 17 3614 . T 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 17 3615 . A 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 17 3616 . T 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 17 3617 . C 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 17 3618 . C 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 17 3619 . T 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 17 3620 . A 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 17 3621 . C 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 17 3622 . T 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 17 3623 . G 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 17 3624 . T 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 17 3625 . G 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 17 3626 . T 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 17 3627 . G 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 17 3628 . T 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 17 3629 . G 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 17 3630 . T 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 17 3631 . C 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 17 3632 . G 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 17 3633 . T 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 17 3634 . T 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 17 3635 . T 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 17 3636 . G 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 17 3637 . T 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 17 3638 . T 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 17 3639 . G 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 17 3640 . T 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 17 3641 . G 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 17 3642 . T 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 17 3643 . T 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 17 3644 . T 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 17 3645 . T 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 17 3646 . C 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 17 3647 . G 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 17 3648 . A 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 17 3649 . C 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 17 3650 . A 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 17 3651 . G 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 17 3652 . C 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 17 3653 . T 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 17 3654 . G 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 17 3655 . T 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 17 3656 . C 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 17 3657 . C 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 17 3658 . G 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 17 3659 . T 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 17 3660 . G 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 17 3661 . T 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 17 3662 . T 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 17 3663 . A 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 17 3664 . T 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 17 3665 . A 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 17 3666 . A 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 17 3667 . T 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 17 3668 . A 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 17 3669 . A 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 17 3670 . T 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 17 3671 . T 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 17 3672 . C 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 17 3673 . C 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 17 3674 . T 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 17 3675 . C 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 17 3676 . T 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 17 3677 . A 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 17 3678 . G 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 17 3679 . T 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 17 3680 . T 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 17 3681 . C 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 17 3682 . A 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 17 3683 . A 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 17 3684 . A 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 17 3685 . T 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 17 3686 . T 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 17 3687 . T 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 17 3688 . A 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 17 3689 . T 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 17 3690 . T 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 17 3691 . C 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 17 3692 . A 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 17 3693 . T 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 17 3694 . T 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 17 3695 . T 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 17 3696 . T 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 17 3697 . T 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 17 3698 . A 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 17 3699 . A 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 17 3700 . C 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 17 3701 . T 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 17 3702 . T 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 17 3703 . C 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 17 3704 . A 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 17 3705 . T 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 17 3706 . A 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 17 3707 . G 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 17 3708 . T 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 17 3709 . A 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 17 3710 . C 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 17 3711 . C 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 17 3712 . A 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 17 3713 . C 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 17 3714 . A 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 17 3715 . T 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 17 3716 . T 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 17 3717 . C 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 17 3718 . T 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 17 3719 . A 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 17 3720 . C 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 17 3721 . A 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 17 3722 . C 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 17 3723 . A 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 17 3724 . C 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 17 3725 . T 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 17 3726 . G 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 17 3727 . C 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 17 3728 . C 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 17 3729 . C 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 17 3730 . A 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 17 3731 . T 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 17 3732 . G 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 17 3733 . T 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 17 3734 . C 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 17 3735 . C 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 17 3736 . C 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 17 3737 . C 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 17 3738 . T 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 17 3739 . C 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 17 3740 . A 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 17 3741 . A 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 17 3742 . G 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 17 3743 . C 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 17 3744 . T 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 17 3745 . T 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 17 3746 . C 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 17 3747 . C 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 17 3748 . C 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 17 3749 . C 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 17 3750 . T 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 17 3751 . G 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 17 3752 . G 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 17 3753 . C 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 17 3754 . T 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 17 3755 . C 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 17 3756 . C 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 17 3757 . T 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 17 3758 . G 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 17 3759 . C 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 17 3760 . A 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 17 3761 . A 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 17 3762 . C 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 17 3763 . C 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 17 3764 . A 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 17 3765 . C 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 17 3766 . A 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 17 3767 . A 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 17 3768 . A 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 17 3769 . T 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 17 3770 . C 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 17 3771 . T 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 17 3772 . A 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 17 3773 . C 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 17 3774 . T 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 17 3775 . C 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 17 3776 . T 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 17 3777 . C 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 17 3778 . T 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 17 3779 . G 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 17 3780 . C 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 17 3781 . C 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 17 3782 . T 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 17 3783 . C 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 17 3784 . T 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 17 3785 . G 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 17 3786 . T 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 17 3787 . G 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 17 3788 . G 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 17 3789 . G 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 17 3790 . T 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 17 3791 . T 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 17 3792 . G A, 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 17 3793 . A 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 17 3794 . C 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 17 3795 . C 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 17 3796 . T 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 17 3797 . A 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 17 3798 . T 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 17 3799 . T 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 17 3800 . C 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 17 3801 . T 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 17 3802 . G 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 17 3803 . G 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 17 3804 . A 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 17 3805 . C 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 17 3806 . A 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 17 3807 . C 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 17 3808 . G 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 17 3809 . T 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 17 3810 . C 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 17 3811 . A C, 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 17 3812 . T 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 17 3813 . A 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 17 3814 . G 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 17 3815 . A 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 17 3816 . A 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 17 3817 . A 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 17 3818 . T 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 17 3819 . A 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 17 3820 . G 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 17 3821 . A 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 17 3822 . G 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 17 3823 . T 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 17 3824 . C 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 17 3825 . C 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 17 3826 . T 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 17 3827 . G 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 17 3828 . C 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 17 3829 . A 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 17 3830 . A 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 17 3831 . C A, 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 17 3832 . A 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 17 3833 . C 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 17 3834 . G 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 17 3835 . T 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 17 3836 . G C, 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 17 3837 . G 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 17 3838 . C 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 17 3839 . C 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 17 3840 . G 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 17 3841 . T 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 17 3842 . C 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 17 3843 . T 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 17 3844 . G 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 17 3845 . T 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 17 3846 . G 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 17 3847 . T 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 17 3848 . C 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 17 3849 . T 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 17 3850 . G 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 17 3851 . G 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 17 3852 . C 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 17 3853 . T 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 17 3854 . T 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 17 3855 . C 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 17 3856 . T 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 17 3857 . C 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 17 3858 . T 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 17 3859 . C 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 17 3860 . G 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 17 3861 . C 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 17 3862 . T 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 17 3863 . T 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 17 3864 . A 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 17 3865 . G 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 17 3866 . C 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 17 3867 . A 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 17 3868 . T 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 17 3869 . C 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 17 3870 . T 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 17 3871 . T 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 17 3872 . G 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 17 3873 . T 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 17 3874 . T 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 17 3875 . T 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 17 3876 . C 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 17 3877 . C 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 17 3878 . A 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 17 3879 . A 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 17 3880 . G 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 17 3881 . G 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 17 3882 . T 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 17 3883 . C 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 17 3884 . C 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 17 3885 . T 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 17 3886 . C 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 17 3887 . C 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 17 3888 . C 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 17 3889 . A 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 17 3890 . C 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 17 3891 . A 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 17 3892 . G 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 17 3893 . T 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 17 3894 . G 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 17 3895 . T 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 17 3896 . A 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 17 3897 . G 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 17 3898 . C 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 17 3899 . A 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 17 3900 . T 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 17 3901 . G 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 17 3902 . C 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 17 3903 . A 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 17 3904 . C 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 17 3905 . C 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 17 3906 . T 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 17 3907 . G 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 17 3908 . C 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 17 3909 . T 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 17 3910 . A 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 17 3911 . C 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 17 3912 . A C, 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 17 3913 . C 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 17 3914 . T 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 17 3915 . C 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 17 3916 . C 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 17 3917 . T 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 17 3918 . T 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 17 3919 . C 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 17 3920 . T 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 17 3921 . T 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 17 3922 . A 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 17 3923 . G 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 17 3924 . G 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 17 3925 . G 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 17 3926 . C 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 17 3927 . T 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 17 3928 . G 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 17 3929 . A 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 17 3930 . T 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 17 3931 . A 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 17 3932 . T 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 17 3933 . T 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 17 3934 . C 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 17 3935 . C 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 17 3936 . A G, 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 17 3937 . C 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 17 3938 . G 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 17 3939 . C 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 17 3940 . A 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 17 3941 . C 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 17 3942 . C 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 17 3943 . T 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 17 3944 . G 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 17 3945 . C 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 17 3946 . T 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 17 3947 . A 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 17 3948 . C 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 17 3949 . A C, 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 17 3950 . C 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 17 3951 . T 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 17 3952 . C 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 17 3953 . C 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 17 3954 . T 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 17 3955 . T 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 17 3956 . C 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 17 3957 . T 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 17 3958 . T 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 17 3959 . A 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 17 3960 . T 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 17 3961 . G 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 17 3962 . G 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 17 3963 . C 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 17 3964 . T 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 17 3965 . G 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 17 3966 . A 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 17 3967 . T 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 17 3968 . A 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 17 3969 . T 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 17 3970 . T 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 17 3971 . C 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 17 3972 . C 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 17 3973 . A 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 17 3974 . C 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 17 3975 . G 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 17 3976 . C 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 17 3977 . A 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 17 3978 . C 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 17 3979 . C 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 17 3980 . T 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 17 3981 . G 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 17 3982 . C 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 17 3983 . T 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 17 3984 . A 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 17 3985 . C 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 17 3986 . A 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 17 3987 . C 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 17 3988 . T 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 17 3989 . C 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 17 3990 . C 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 17 3991 . T 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 17 3992 . T 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 17 3993 . C 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 17 3994 . T 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 17 3995 . T 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 17 3996 . A 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 17 3997 . G C, 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 17 3998 . G 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 17 3999 . G A, 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 17 4000 . C 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 17 4001 . T 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 17 4002 . G 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 17 4003 . A 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 17 4004 . T 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 17 4005 . A 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 17 4006 . T 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 17 4007 . T G, 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 17 4008 . C 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 17 4009 . C 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 17 4010 . A 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 17 4011 . C 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 17 4012 . A 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 17 4013 . C 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 17 4014 . A 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 17 4015 . C 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 17 4016 . C 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 17 4017 . C 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 17 4018 . G 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 17 4019 . C 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 17 4020 . T 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 17 4021 . A 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 17 4022 . C 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 17 4023 . A 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 17 4024 . C 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 17 4025 . T 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 17 4026 . C 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 17 4027 . C 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 17 4028 . T 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 17 4029 . T 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 17 4030 . C 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 17 4031 . T 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 17 4032 . T 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 17 4033 . A 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 17 4034 . G 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 17 4035 . G T, 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 17 4036 . G 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 17 4037 . C 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 17 4038 . T 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 17 4039 . G 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 17 4040 . A 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 17 4041 . T 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 17 4042 . A 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 17 4043 . T 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 17 4044 . T 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 17 4045 . C 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 17 4046 . C 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 17 4047 . A 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 17 4048 . C 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 17 4049 . G 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 17 4050 . C 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 17 4051 . A 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 17 4052 . C 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 17 4053 . C 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 17 4054 . C 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 17 4055 . G 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 17 4056 . C 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 17 4057 . T 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 17 4058 . A 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 17 4059 . C 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 17 4060 . A 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 17 4061 . C 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 17 4062 . T 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 17 4063 . C 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 17 4064 . C 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 17 4065 . T 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 17 4066 . T 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 17 4067 . C 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 17 4068 . T 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 17 4069 . T 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 17 4070 . A 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 17 4071 . G 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 17 4072 . G 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 17 4073 . G 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 17 4074 . C 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 17 4075 . T 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 17 4076 . G 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 17 4077 . A 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 17 4078 . T 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 17 4079 . A 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 17 4080 . T 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 17 4081 . T 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 17 4082 . C 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 17 4083 . C 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 17 4084 . A 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 17 4085 . C 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 17 4086 . G 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 17 4087 . C 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 17 4088 . A 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 17 4089 . C 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 17 4090 . C 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 17 4091 . T 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 17 4092 . G 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 17 4093 . C 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 17 4094 . T 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 17 4095 . A 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 17 4096 . C 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 17 4097 . A 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 17 4098 . C 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 17 4099 . T 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 17 4100 . C 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 17 4101 . C 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 bcftools-1.21/test/mpileup/000077500000000000000000000000001467060157400157145ustar00rootroot00000000000000bcftools-1.21/test/mpileup/annot-NMBZ.1.1.out000066400000000000000000000145441467060157400206360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample chr19 69 . G C,<*> 0 . DP=46;I16=18,21,2,3,1377,50689,217,10339,2340,140400,266,14324,759,16653,92,1754;QS=0.868222,0.131778,0;VDB=0.216674;SGB=-0.590765;RPBZ=0.0924924;MQBZ=-4.95028;MQSBZ=-0.485415;BQBZ=-0.0931785;NMBZ=6.54221;SCBZ=6.54221;MQ0F=0 PL 60,0,255,177,255,255 chr19 70 . G <*> 0 . DP=47;I16=19,25,0,0,1638,63732,0,0,2606,154724,0,0,829,18007,0,0;QS=1,0;MQ0F=0 PL 0,132,255 chr19 71 . T <*> 0 . DP=47;I16=19,25,0,0,1488,54040,0,0,2606,154724,0,0,827,17989,0,0;QS=1,0;MQ0F=0 PL 0,132,255 chr19 72 . G A,<*> 0 . DP=48;I16=18,22,2,3,1377,49347,203,9477,2400,144000,266,14324,733,16223,92,1796;QS=0.874841,0.125159,0;VDB=0.206846;SGB=-0.590765;RPBZ=0.415523;MQBZ=-5.01073;MQSBZ=-0.448951;BQBZ=0.145086;NMBZ=6.61856;SCBZ=6.61856;MQ0F=0 PL 48,0,255,169,255,255 chr19 73 . G <*> 0 . DP=48;I16=20,25,0,0,1608,61094,0,0,2666,158324,0,0,823,18049,0,0;QS=1,0;MQ0F=0 PL 0,135,255 chr19 74 . T <*> 0 . DP=48;I16=20,25,0,0,1478,53810,0,0,2666,158324,0,0,820,18080,0,0;QS=1,0;MQ0F=0 PL 0,135,255 chr19 75 . G <*> 0 . DP=48;I16=20,25,0,0,1617,61719,0,0,2666,158324,0,0,813,17961,0,0;QS=1,0;MQ0F=0 PL 0,135,255 chr19 76 . A C,<*> 0 . DP=47;I16=18,21,2,3,1383,50589,220,10546,2340,140400,266,14324,715,15927,92,1964;QS=0.867085,0.132915,0;VDB=0.187998;SGB=-0.590765;RPBZ=0.573514;MQBZ=-4.95028;MQSBZ=-0.485415;BQBZ=0.556487;NMBZ=6.54221;SCBZ=5.78316;MQ0F=0 PL 63,0,255,180,255,255 chr19 77 . G <*> 0 . DP=47;I16=20,24,0,0,1639,63567,0,0,2606,154724,0,0,799,17769,0,0;QS=1,0;MQ0F=0 PL 0,132,255 chr19 78 . G C,<*> 0 . DP=46;I16=17,21,2,3,1392,52920,202,9494,2280,136800,266,14324,702,15700,88,1896;QS=0.87768,0.12232,0;VDB=0.181959;SGB=-0.590765;RPBZ=0.739183;MQBZ=-4.88906;MQSBZ=-0.44293;BQBZ=-0.380581;NMBZ=6.46493;SCBZ=5.71324;MQ0F=0 PL 51,0,255,166,255,255 chr19 79 . G <*> 0 . DP=45;I16=18,24,0,0,1560,60778,0,0,2486,147524,0,0,780,17370,0,0;QS=1,0;MQ0F=0 PL 0,126,255 chr19 80 . G <*> 0 . DP=43;I16=17,23,0,0,1448,55202,0,0,2366,140324,0,0,771,17137,0,0;QS=1,0;MQ0F=0 PL 0,120,255 chr19 81 . C <*> 0 . DP=43;I16=17,23,0,0,1493,58329,0,0,2366,140324,0,0,762,16946,0,0;QS=1,0;MQ0F=0 PL 0,120,255 chr19 82 . T <*> 0 . DP=43;I16=17,23,0,0,1463,56415,0,0,2366,140324,0,0,753,16797,0,0;QS=1,0;MQ0F=0 PL 0,120,255 chr19 83 . G <*> 0 . DP=41;I16=16,22,0,0,1442,57270,0,0,2246,133124,0,0,745,16639,0,0;QS=1,0;MQ0F=0 PL 0,114,255 chr19 84 . C <*> 0 . DP=41;I16=16,22,0,0,1395,54045,0,0,2246,133124,0,0,736,16470,0,0;QS=1,0;MQ0F=0 PL 0,114,255 chr19 85 . G <*> 0 . DP=40;I16=15,23,0,0,1396,53802,0,0,2246,133124,0,0,750,16812,0,0;QS=1,0;MQ0F=0 PL 0,114,255 chr19 86 . A <*> 0 . DP=40;I16=15,23,0,0,1320,47524,0,0,2246,133124,0,0,737,16465,0,0;QS=1,0;MQ0F=0 PL 0,114,255 chr19 87 . C <*> 0 . DP=39;I16=15,22,0,0,1325,50283,0,0,2186,129524,0,0,724,16106,0,0;QS=1,0;MQ0F=0 PL 0,111,255 chr19 88 . C <*> 0 . DP=38;I16=14,23,0,0,1377,52341,0,0,2186,129524,0,0,735,16311,0,0;QS=1,0;MQ0F=0 PL 0,111,255 chr19 89 . G <*> 0 . DP=37;I16=13,23,0,0,1343,51159,0,0,2126,125924,0,0,720,15832,0,0;QS=1,0;MQ0F=0 PL 0,108,255 chr19 90 . C <*> 0 . DP=37;I16=13,23,0,0,1311,49173,0,0,2126,125924,0,0,704,15346,0,0;QS=1,0;MQ0F=0 PL 0,108,255 chr19 91 . A G,<*> 0 . DP=37;I16=13,18,0,5,1128,42894,164,5518,1860,111600,266,14324,579,12347,107,2459;QS=0.873065,0.126935,0;VDB=0.0081677;SGB=-0.590765;RPBZ=1.60224;MQBZ=-4.43656;MQSBZ=-1.33955;BQBZ=-1.63294;NMBZ=5.89499;SCBZ=5.1969;MQ0F=0 PL 27,0,255,121,255,255 chr19 92 . T <*> 0 . DP=36;I16=13,23,0,0,1262,45858,0,0,2126,125924,0,0,668,14314,0,0;QS=1,0;MQ0F=0 PL 0,108,255 chr19 93 . C <*> 0 . DP=36;I16=13,23,0,0,1250,44748,0,0,2126,125924,0,0,649,13819,0,0;QS=1,0;MQ0F=0 PL 0,108,255 chr19 94 . G <*> 0 . DP=35;I16=12,23,0,0,1262,46192,0,0,2066,122324,0,0,631,13369,0,0;QS=1,0;MQ0F=0 PL 0,105,255 chr19 95 . T <*> 0 . DP=35;I16=12,23,0,0,1163,41003,0,0,2066,122324,0,0,610,12816,0,0;QS=1,0;MQ0F=0 PL 0,105,255 chr19 96 . G <*> 0 . DP=34;I16=11,23,0,0,1178,41726,0,0,2006,118724,0,0,589,12261,0,0;QS=1,0;MQ0F=0 PL 0,102,255 chr19 97 . C <*> 0 . DP=34;I16=11,23,0,0,1191,42673,0,0,2006,118724,0,0,568,11752,0,0;QS=1,0;MQ0F=0 PL 0,102,255 chr19 98 . C <*> 0 . DP=33;I16=11,22,0,0,1153,41759,0,0,1946,115124,0,0,546,11188,0,0;QS=1,0;MQ0F=0 PL 0,99,255 chr19 99 . C G,<*> 0 . DP=33;I16=11,17,0,5,1016,37202,178,6402,1680,100800,266,14324,436,8720,86,1850;QS=0.850921,0.149079,0;VDB=0.00429937;SGB=-0.590765;RPBZ=2.38675;MQBZ=-4.22751;MQSBZ=-1.26321;BQBZ=-0.583488;NMBZ=5.63252;SCBZ=4.95871;MQ0F=0 PL 45,0,255,129,255,255 bcftools-1.21/test/mpileup/annot-NMBZ.1.bam000066400000000000000000000167411467060157400204300ustar00rootroot00000000000000‹ÿBC¨srôeœÎÀÀààáÂæge¨gÊìo•œŸ_”’™—X’ÊåÈìg•œQdhÉéTabÎåäÎéébU”ÎìkUœ˜[TòJòósŠ9ül°Á†&º†ºé¦i¦©&‰†œÎ>pi…²ÌÔrÝ$Ý|…ÄÄD½¤Ä\0 ”çb: ˆÁÖ3L²ÃâDÁ±‹ÿBC¥\[Œ#éUölfÆ==³ã¶»ÚeW¹þkÝšÜ\e»|É&ãv{gzYe3#”,„låDŠ6ÁĄ̃‚@,¼ A‘"qã! 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TTTGTTTACCTGTGTTGTTTGTGTGCTCCCTCTGCGTGCTGGCTATCATGTCAGGTACTG GTCTGGACCGGAGAGAAACTGTGGATGTCTGTCAACACAACAGAAAAAGTGACTGATTAG TTAGATGTAACTAATTTCAACTATCTAGTCTTCCTCTAAAGACCCCTACTTTAACACAAT ACAAATTACATCTAGATATTTGTTAT bcftools-1.21/test/mpileup/indel-AD.1.fa.fai000066400000000000000000000000251467060157400204730ustar00rootroot00000000000000000000F 686 21 60 61 bcftools-1.21/test/mpileup/indel-AD.1.out000066400000000000000000001470051467060157400201700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 000000F 392 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,32:1,0 000000F 393 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,32:1,0 000000F 394 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,32:1,0 000000F 395 . G <*> 0 . DP=3;I16=1,2,0,0,76,2242,0,0,180,10800,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,73:3,0 000000F 396 . T <*> 0 . DP=3;I16=1,2,0,0,86,2882,0,0,180,10800,0,0,6,18,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,83:3,0 000000F 397 . A <*> 0 . DP=3;I16=1,2,0,0,80,2554,0,0,180,10800,0,0,9,33,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,77:3,0 000000F 398 . C <*> 0 . DP=3;I16=1,2,0,0,75,2309,0,0,180,10800,0,0,12,54,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,72:3,0 000000F 399 . T <*> 0 . DP=3;I16=1,2,0,0,86,2582,0,0,180,10800,0,0,15,81,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,82:3,0 000000F 400 . C T,<*> 0 . DP=3;I16=1,1,0,1,63,2165,12,144,120,7200,60,3600,13,89,5,25;QS=0.84,0.16,0;SGB=-0.379885;RPBZ=-0.707107;MQBZ=0;MQSBZ=0;BQBZ=-1.22474;SCBZ=0;MQ0F=0 PL:AD 3,0,54,9,57,61:2,1,0 000000F 401 . G <*> 0 . DP=3;I16=1,2,0,0,65,1969,0,0,180,10800,0,0,21,153,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,62:3,0 000000F 402 . C <*> 0 . DP=5;I16=1,3,0,0,83,2041,0,0,240,14400,0,0,24,198,0,0;QS=1,0;MQ0F=0 PL:AD 0,12,75:4,0 000000F 403 . A <*> 0 . DP=5;I16=2,3,0,0,102,2818,0,0,300,18000,0,0,29,251,0,0;QS=1,0;MQ0F=0 PL:AD 0,15,91:5,0 000000F 404 . T <*> 0 . DP=5;I16=2,3,0,0,141,4875,0,0,300,18000,0,0,34,314,0,0;QS=1,0;MQ0F=0 PL:AD 0,15,127:5,0 000000F 405 . G <*> 0 . DP=6;I16=3,3,0,0,175,6043,0,0,360,21600,0,0,39,387,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,150:6,0 000000F 406 . A T,<*> 0 . DP=6;I16=3,2,0,1,143,5019,12,144,300,18000,60,3600,34,350,11,121;QS=0.922581,0.0774194,0;SGB=-0.379885;RPBZ=0.603023;MQBZ=0;MQSBZ=0;BQBZ=-0.948683;SCBZ=-0.447214;MQ0F=0 PL:AD 0,5,117,15,120,122:5,1,0 000000F 407 . G <*> 0 . DP=6;I16=3,3,0,0,170,5748,0,0,360,21600,0,0,51,567,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,148:6,0 000000F 408 . A <*> 0 . DP=6;I16=3,3,0,0,150,4818,0,0,360,21600,0,0,57,675,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,130:6,0 000000F 409 . G <*> 0 . DP=6;I16=3,3,0,0,194,6940,0,0,360,21600,0,0,63,795,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,166:6,0 000000F 410 . T <*> 0 . DP=7;I16=4,3,0,0,157,4587,0,0,420,25200,0,0,88,1288,0,0;QS=1,0;MQ0F=0 PL:AD 0,21,132:7,0 000000F 411 . T <*> 0 . DP=8;I16=5,3,0,0,255,8901,0,0,480,28800,0,0,115,1871,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,196:8,0 000000F 412 . A G,<*> 0 . DP=8;I16=5,2,0,1,235,8721,8,64,420,25200,60,3600,113,2009,10,100;QS=0.967078,0.0329218,0;SGB=-0.379885;RPBZ=0;MQBZ=0;MQSBZ=0;BQBZ=-1.62747;SCBZ=-0.75;MQ0F=0 PL:AD 0,14,175,21,178,176:7,1,0 000000F 413 . T <*> 0 . DP=9;I16=5,4,0,0,288,10546,0,0,540,32400,0,0,131,2363,0,0;QS=1,0;MQ0F=0 PL:AD 0,27,214:9,0 000000F 414 . G <*> 0 . DP=9;I16=5,4,0,0,317,12083,0,0,540,32400,0,0,140,2634,0,0;QS=1,0;MQ0F=0 PL:AD 0,27,236:9,0 000000F 415 . T G,<*> 0 . DP=9;I16=5,3,0,1,291,10937,22,484,480,28800,60,3600,136,2754,13,169;QS=0.929712,0.0702875,0;SGB=-0.379885;RPBZ=0.195283;MQBZ=0;MQSBZ=0;BQBZ=-1.5;SCBZ=-0.690269;MQ0F=0 PL:AD 0,5,202,24,205,214:8,1,0 000000F 416 . G C,<*> 0 . DP=10;I16=6,3,0,1,324,11944,12,144,540,32400,60,3600,144,3034,14,196;QS=0.964286,0.0357143,0;SGB=-0.379885;RPBZ=0.350285;MQBZ=0;MQSBZ=0;BQBZ=-1.62698;SCBZ=-0.642529;MQ0F=0 PL:AD 0,17,225,27,228,228:9,1,0 000000F 417 . T <*> 0 . DP=10;I16=6,4,0,0,364,13992,0,0,600,36000,0,0,166,3454,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,255:10,0 000000F 418 . A <*> 0 . DP=10;I16=6,4,0,0,360,13680,0,0,600,36000,0,0,173,3643,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,254:10,0 000000F 419 . A <*> 0 . DP=10;I16=6,4,0,0,344,13112,0,0,600,36000,0,0,180,3846,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,242:10,0 000000F 420 . A C,<*> 0 . DP=11;I16=7,3,0,1,306,11440,12,144,600,36000,60,3600,190,4180,18,324;QS=0.962382,0.0376176,0;SGB=-0.379885;RPBZ=0.476513;MQBZ=0;MQSBZ=0;BQBZ=-1.00766;SCBZ=-0.73252;MQ0F=0 PL:AD 0,20,212,30,215,215:10,1,0 000000F 421 . A <*> 0 . DP=12;I16=8,4,0,0,388,13950,0,0,720,43200,0,0,236,5160,0,0;QS=1,0;MQ0F=0 PL:AD 0,36,255:12,0 000000F 422 . C <*> 0 . DP=13;I16=8,5,0,0,484,18266,0,0,780,46800,0,0,243,5389,0,0;QS=1,0;MQ0F=0 PL:AD 0,39,255:13,0 000000F 423 . A <*> 0 . DP=15;I16=9,6,0,0,509,18579,0,0,900,54000,0,0,266,5858,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 424 . G <*> 0 . DP=15;I16=9,6,0,0,516,19368,0,0,900,54000,0,0,276,6150,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 425 . A <*> 0 . DP=15;I16=9,6,0,0,516,19668,0,0,900,54000,0,0,284,6360,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 426 . G T,<*> 0 . DP=15;I16=9,5,0,1,519,20109,12,144,840,50400,60,3600,288,6570,4,16;QS=0.977401,0.0225989,0;SGB=-0.379885;RPBZ=-1.28103;MQBZ=0;MQSBZ=0;BQBZ=-1.70698;SCBZ=-0.879593;MQ0F=0 PL:AD 0,31,255,42,255,255:14,1,0 000000F 427 . C <*> 0 . DP=15;I16=9,6,0,0,550,21100,0,0,900,54000,0,0,300,6828,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 428 . T <*> 0 . DP=15;I16=9,6,0,0,521,19363,0,0,900,54000,0,0,306,6984,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 429 . C A,<*> 0 . DP=17;I16=10,6,0,1,533,19507,12,144,960,57600,60,3600,287,6527,25,625;QS=0.977982,0.0220183,0;SGB=-0.379885;RPBZ=1.33584;MQBZ=0;MQSBZ=0;BQBZ=-1.55274;SCBZ=-0.887279;MQ0F=0 PL:AD 0,37,255,48,255,255:16,1,0 000000F 430 . A <*> 0 . DP=18;I16=10,8,0,0,583,20803,0,0,1080,64800,0,0,320,7334,0,0;QS=1,0;MQ0F=0 PL:AD 0,54,255:18,0 000000F 431 . A <*> 0 . DP=19;I16=10,8,0,0,616,23012,0,0,1080,64800,0,0,328,7482,0,0;QS=1,0;MQ0F=0 PL:AD 0,54,255:18,0 000000F 432 . T <*> 0 . DP=19;I16=11,8,0,0,682,26264,0,0,1140,68400,0,0,337,7647,0,0;QS=1,0;MQ0F=0 PL:AD 0,57,255:19,0 000000F 433 . T <*> 0 . DP=19;I16=11,8,0,0,696,26452,0,0,1140,68400,0,0,346,7830,0,0;QS=1,0;MQ0F=0 PL:AD 0,57,255:19,0 000000F 434 . T <*> 0 . DP=19;I16=11,8,0,0,678,25728,0,0,1140,68400,0,0,354,7980,0,0;QS=1,0;MQ0F=0 PL:AD 0,57,255:19,0 000000F 435 . T <*> 0 . DP=20;I16=11,9,0,0,717,26931,0,0,1200,72000,0,0,362,8146,0,0;QS=1,0;MQ0F=0 PL:AD 0,60,255:20,0 000000F 436 . A C,<*> 0 . DP=21;I16=11,9,0,1,728,28034,12,144,1200,72000,60,3600,346,7704,25,625;QS=0.983784,0.0162162,0;SGB=-0.379885;RPBZ=0.909477;MQBZ=0;MQSBZ=0;BQBZ=-1.66309;SCBZ=-0.82685;MQ0F=0 PL:AD 0,49,255,60,255,255:20,1,0 000000F 437 . T <*> 0 . DP=21;I16=11,10,0,0,770,29698,0,0,1260,75600,0,0,381,8531,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 438 . T <*> 0 . DP=22;I16=11,10,0,0,726,26976,0,0,1260,75600,0,0,391,8753,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 439 . T <*> 0 . DP=25;I16=14,10,0,0,804,30038,0,0,1440,86400,0,0,444,9912,0,0;QS=1,0;MQ0F=0 PL:AD 0,72,255:24,0 000000F 440 . T A,<*> 0 . DP=27;I16=15,11,1,0,896,33856,12,144,1560,93600,60,3600,455,10163,25,625;QS=0.986784,0.0132159,0;SGB=-0.379885;RPBZ=1.28585;MQBZ=0;MQSBZ=0;BQBZ=-1.41134;SCBZ=0.48519;MQ0F=0 PL:AD 0,66,255,78,255,255:26,1,0 000000F 441 . G <*> 0 . DP=29;I16=17,11,0,0,1033,39137,0,0,1680,100800,0,0,495,11163,0,0;QS=1,0;MQ0F=0 PL:AD 0,84,255:28,0 000000F 442 . T <*> 0 . DP=29;I16=18,11,0,0,1067,41223,0,0,1740,104400,0,0,531,11951,0,0;QS=1,0;MQ0F=0 PL:AD 0,87,255:29,0 000000F 443 . A <*> 0 . DP=31;I16=20,11,0,0,1078,40562,0,0,1860,111600,0,0,544,12226,0,0;QS=1,0;MQ0F=0 PL:AD 0,93,255:31,0 000000F 444 . T <*> 0 . DP=31;I16=20,11,0,0,1124,43000,0,0,1860,111600,0,0,559,12529,0,0;QS=1,0;MQ0F=0 PL:AD 0,93,255:31,0 000000F 445 . T <*> 0 . DP=32;I16=20,11,0,0,1050,38808,0,0,1860,111600,0,0,574,12862,0,0;QS=1,0;MQ0F=0 PL:AD 0,93,255:31,0 000000F 446 . T <*> 0 . DP=34;I16=22,11,0,0,1205,45921,0,0,1980,118800,0,0,611,13703,0,0;QS=1,0;MQ0F=0 PL:AD 0,99,255:33,0 000000F 447 . A <*> 0 . DP=35;I16=23,12,0,0,1177,43259,0,0,2100,126000,0,0,650,14620,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 448 . T <*> 0 . DP=35;I16=23,12,0,0,1220,45736,0,0,2100,126000,0,0,667,15037,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 449 . T <*> 0 . DP=35;I16=23,12,0,0,1249,47703,0,0,2100,126000,0,0,679,15245,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 450 . G <*> 0 . DP=38;I16=25,13,0,0,1449,56453,0,0,2280,136800,0,0,715,16059,0,0;QS=1,0;MQ0F=0 PL:AD 0,114,255:38,0 000000F 451 . T A,<*> 0 . DP=43;I16=24,16,0,1,1485,57079,12,144,2400,144000,60,3600,708,15882,0,0;QS=0.991984,0.00801603,0;SGB=-0.379885;RPBZ=-1.56545;MQBZ=0;MQSBZ=0;BQBZ=-1.91213;SCBZ=-0.839032;MQ0F=0 PL:AD 0,107,255,120,255,255:40,1,0 000000F 452 . G T,<*> 0 . DP=45;I16=24,18,0,1,1541,58723,12,144,2520,151200,60,3600,707,15841,23,529;QS=0.992273,0.00772698,0;SGB=-0.379885;RPBZ=0.645561;MQBZ=0;MQSBZ=0;BQBZ=-1.75577;SCBZ=0.629801;MQ0F=0 PL:AD 0,113,255,126,255,255:42,1,0 000000F 453 . C <*> 0 . DP=45;I16=24,19,0,0,1623,65335,0,0,2580,154800,0,0,753,16853,0,0;QS=1,0;MQ0F=0 PL:AD 0,129,255:43,0 000000F 454 . A C,<*> 0 . DP=47;I16=24,20,1,0,1699,68295,12,144,2640,158400,60,3600,774,17286,25,625;QS=0.992987,0.00701344,0;SGB=-0.379885;RPBZ=1.46482;MQBZ=0;MQSBZ=0;BQBZ=-1.87433;SCBZ=0.550575;MQ0F=0 PL:AD 0,119,255,132,255,255:44,1,0 000000F 455 . G <*> 0 . DP=48;I16=26,20,0,0,1807,74553,0,0,2760,165600,0,0,823,18385,0,0;QS=1,0;MQ0F=0 PL:AD 0,138,255:46,0 000000F 456 . T <*> 0 . DP=49;I16=26,21,0,0,1757,69583,0,0,2820,169200,0,0,845,18853,0,0;QS=1,0;MQ0F=0 PL:AD 0,141,255:47,0 000000F 457 . T <*> 0 . DP=49;I16=26,21,0,0,1836,73528,0,0,2820,169200,0,0,866,19264,0,0;QS=1,0;MQ0F=0 PL:AD 0,141,255:47,0 000000F 458 . A <*> 0 . DP=50;I16=26,22,0,0,1817,72337,0,0,2880,172800,0,0,887,19717,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 459 . G <*> 0 . DP=50;I16=26,22,0,0,1791,70171,0,0,2880,172800,0,0,909,20213,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 460 . A <*> 0 . DP=49;I16=26,22,0,0,1675,63873,0,0,2880,172800,0,0,923,20689,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 461 . A T,C,<*> 0 . DP=52;I16=25,22,1,1,1650,63298,24,288,2820,169200,120,7200,927,21061,17,145;QS=0.985663,0.00716846,0.00716846,0;VDB=0.06;SGB=-0.453602;RPBZ=-1.92231;MQBZ=0;MQSBZ=0;BQBZ=-2.2578;SCBZ=-0.055422;MQ0F=0 PL:AD 0,128,255,128,255,255,141,255,255,255:47,1,1,0 000000F 462 . A T,<*> 0 . DP=52;I16=26,22,0,1,1705,65163,12,144,2880,172800,60,3600,955,21615,10,100;QS=0.993011,0.00698893,0;SGB=-0.379885;RPBZ=-1.09702;MQBZ=0;MQSBZ=0;BQBZ=-1.74927;SCBZ=-0.853241;MQ0F=0 PL:AD 0,130,255,144,255,255:48,1,0 000000F 463 . A <*> 0 . DP=52;I16=26,24,0,0,1836,71956,0,0,3000,180000,0,0,996,22366,0,0;QS=1,0;MQ0F=0 PL:AD 0,151,255:50,0 000000F 464 . T G,<*> 0 . DP=52;I16=26,23,0,1,1873,73813,12,144,2940,176400,60,3600,993,22355,25,625;QS=0.993634,0.00636605,0;SGB=-0.379885;RPBZ=0.173386;MQBZ=0;MQSBZ=0;BQBZ=-1.93908;SCBZ=-0.840331;MQ0F=0 PL:AD 0,133,255,148,255,255:49,1,0 000000F 465 . A <*> 0 . DP=52;I16=26,24,0,0,1950,78232,0,0,3000,180000,0,0,1039,23587,0,0;QS=1,0;MQ0F=0 PL:AD 0,151,255:50,0 000000F 466 . A C,<*> 0 . DP=52;I16=25,24,1,0,1858,74740,12,144,2940,176400,60,3600,1033,23509,25,625;QS=0.993583,0.00641711,0;SGB=-0.379885;RPBZ=-1.24865;MQBZ=0;MQSBZ=0;BQBZ=-1.79438;SCBZ=1.87165;MQ0F=0 PL:AD 0,133,255,148,255,255:49,1,0 000000F 467 . T <*> 0 . DP=53;I16=26,25,0,0,1890,74962,0,0,3060,183600,0,0,1076,24668,0,0;QS=1,0;MQ0F=0 PL:AD 0,154,255:51,0 000000F 468 . A <*> 0 . DP=54;I16=27,25,0,0,1967,78281,0,0,3120,187200,0,0,1095,25239,0,0;QS=1,0;MQ0F=0 PL:AD 0,157,255:52,0 000000F 469 . T <*> 0 . DP=54;I16=27,25,0,0,2046,83348,0,0,3120,187200,0,0,1113,25747,0,0;QS=1,0;MQ0F=0 PL:AD 0,157,255:52,0 000000F 470 . G <*> 0 . DP=55;I16=28,25,0,0,2047,81939,0,0,3180,190800,0,0,1131,26291,0,0;QS=1,0;MQ0F=0 PL:AD 0,160,255:53,0 000000F 471 . A <*> 0 . DP=56;I16=28,26,0,0,2028,80100,0,0,3240,194400,0,0,1150,26872,0,0;QS=1,0;MQ0F=0 PL:AD 0,163,255:54,0 000000F 472 . T <*> 0 . DP=59;I16=29,28,0,0,2122,83726,0,0,3420,205200,0,0,1191,27925,0,0;QS=1,0;MQ0F=0 PL:AD 0,172,255:57,0 000000F 473 . C A,G,<*> 0 . DP=63;I16=19,15,12,13,1263,49285,963,39221,2040,122400,1500,90000,705,16449,548,12960;QS=0.567385,0.427224,0.00539084,0;VDB=1.64281e-06;SGB=-0.692914;RPBZ=1.05908;MQBZ=0;MQSBZ=0;BQBZ=1.40915;SCBZ=0.597801;MQ0F=0 PL:AD 255,0,255,255,255,255,255,255,255,255:34,24,1,0 000000F 474 . A <*> 0 . DP=64;I16=33,28,0,0,2172,84276,0,0,3660,219600,0,0,1296,30488,0,0;QS=1,0;MQ0F=0 PL:AD 0,184,255:61,0 000000F 475 . A <*> 0 . DP=64;I16=34,28,0,0,2092,79478,0,0,3720,223200,0,0,1322,31258,0,0;QS=1,0;MQ0F=0 PL:AD 0,187,255:62,0 000000F 476 . A G,<*> 0 . DP=65;I16=34,28,0,1,2176,83678,12,144,3720,223200,60,3600,1319,31299,25,625;QS=0.994516,0.00548446,0;SGB=-0.379885;RPBZ=1.04564;MQBZ=0;MQSBZ=0;BQBZ=-1.59705;SCBZ=0.713967;MQ0F=0 PL:AD 0,172,255,187,255,255:62,1,0 000000F 477 . T G,<*> 0 . DP=65;I16=34,28,0,1,2352,93436,12,144,3720,223200,60,3600,1338,31806,25,625;QS=0.994924,0.00507614,0;SGB=-0.379885;RPBZ=-0.687896;MQBZ=0;MQSBZ=0;BQBZ=-1.84472;SCBZ=-0.892396;MQ0F=0 PL:AD 0,172,255,187,255,255:62,1,0 000000F 478 . C <*> 0 . DP=65;I16=34,29,0,0,2376,94566,0,0,3780,226800,0,0,1381,32925,0,0;QS=1,0;MQ0F=0 PL:AD 0,190,255:63,0 000000F 479 . T G,<*> 0 . DP=68;I16=36,29,0,1,2467,98357,12,144,3900,234000,60,3600,1416,33712,21,441;QS=0.995159,0.00484066,0;SGB=-0.379885;RPBZ=-0.787962;MQBZ=0;MQSBZ=0;BQBZ=-1.86106;SCBZ=-0.927153;MQ0F=0 PL:AD 0,180,255,196,255,255:65,1,0 000000F 480 . G <*> 0 . DP=70;I16=38,30,0,0,2563,101527,0,0,4080,244800,0,0,1495,35435,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 481 . T <*> 0 . DP=70;I16=38,30,0,0,2521,98551,0,0,4080,244800,0,0,1514,35994,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 482 . T G,<*> 0 . DP=70;I16=37,30,1,0,2575,103005,12,144,4020,241200,60,3600,1518,36344,14,196;QS=0.995361,0.00463858,0;SGB=-0.379885;RPBZ=-0.892198;MQBZ=0;MQSBZ=0;BQBZ=-1.93937;SCBZ=-0.948507;MQ0F=0 PL:AD 0,186,255,202,255,255:67,1,0 000000F 483 . T <*> 0 . DP=70;I16=38,30,0,0,2646,106206,0,0,4080,244800,0,0,1549,37071,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 484 . G <*> 0 . DP=70;I16=38,30,0,0,2659,107225,0,0,4080,244800,0,0,1565,37585,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 485 . T <*> 0 . DP=70;I16=38,30,0,0,2618,104932,0,0,4080,244800,0,0,1578,37978,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 486 . T <*> 0 . DP=70;I16=38,30,0,0,2589,103545,0,0,4080,244800,0,0,1589,38295,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 487 . T <*> 0 . DP=73;I16=38,33,0,0,2694,107284,0,0,4260,255600,0,0,1599,38583,0,0;QS=1,0;MQ0F=0 PL:AD 0,214,255:71,0 000000F 488 . A G,<*> 0 . DP=76;I16=41,32,0,1,2640,102296,8,64,4380,262800,60,3600,1679,40447,1,1;QS=0.996979,0.00302115,0;SGB=-0.379885;RPBZ=-1.52228;MQBZ=0;MQSBZ=0;BQBZ=-1.89405;SCBZ=-0.946449;MQ0F=0 PL:AD 0,204,255,220,255,255:73,1,0 000000F 489 . C A,<*> 0 . DP=79;I16=43,33,0,1,2694,103126,12,144,4560,273600,60,3600,1715,41273,25,625;QS=0.995565,0.00443459,0;SGB=-0.379885;RPBZ=-0.495167;MQBZ=0;MQSBZ=0;BQBZ=-1.58784;SCBZ=-0.974263;MQ0F=0 PL:AD 0,213,255,229,255,255:76,1,0 000000F 490 . C <*> 0 . DP=80;I16=43,35,0,0,2796,107040,0,0,4680,280800,0,0,1782,43020,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 491 . T <*> 0 . DP=80;I16=43,35,0,0,2910,113818,0,0,4680,280800,0,0,1798,43500,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 492 . G <*> 0 . DP=81;I16=43,35,0,0,3089,125687,0,0,4680,280800,0,0,1814,44012,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 493 . T <*> 0 . DP=81;I16=43,35,0,0,2986,119178,0,0,4680,280800,0,0,1829,44505,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 494 . G <*> 0 . DP=81;I16=43,35,0,0,3060,125030,0,0,4680,280800,0,0,1842,44926,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 495 . T <*> 0 . DP=84;I16=45,36,0,0,3053,121389,0,0,4860,291600,0,0,1898,46292,0,0;QS=1,0;MQ0F=0 PL:AD 0,244,255:81,0 000000F 496 . T <*> 0 . DP=87;I16=47,37,0,0,3238,128760,0,0,5040,302400,0,0,1917,46777,0,0;QS=1,0;MQ0F=0 PL:AD 0,253,255:84,0 000000F 497 . G <*> 0 . DP=87;I16=47,37,0,0,3280,132640,0,0,5040,302400,0,0,1933,47227,0,0;QS=1,0;MQ0F=0 PL:AD 0,253,255:84,0 000000F 498 . T <*> 0 . DP=88;I16=48,37,0,0,3081,120187,0,0,5100,306000,0,0,1971,48181,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 499 . T C,<*> 0 . DP=89;I16=48,36,0,1,3190,126958,8,64,5040,302400,60,3600,1957,47809,25,625;QS=0.997498,0.00250156,0;SGB=-0.379885;RPBZ=-0.305833;MQBZ=0;MQSBZ=0;BQBZ=-1.95559;SCBZ=-1.05778;MQ0F=0 PL:AD 0,237,255,253,255,255:84,1,0 000000F 500 . T G,A,<*> 0 . DP=92;I16=50,37,1,1,3308,133104,24,288,5220,313200,120,7200,1986,48376,50,1250;QS=0.992797,0.00360144,0.00360144,0;VDB=0.32;SGB=-0.453602;RPBZ=0.41539;MQBZ=0;MQSBZ=0;BQBZ=-2.60206;SCBZ=-1.0009;MQ0F=0 PL:AD 0,245,255,245,255,255,255,255,255,255:87,1,1,0 000000F 501 . G <*> 0 . DP=97;I16=53,40,0,0,3485,138049,0,0,5580,334800,0,0,2050,49962,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:93,0 000000F 502 . T A,<*> 0 . DP=98;I16=53,40,1,0,3391,132771,12,144,5580,334800,60,3600,2065,50183,25,625;QS=0.996476,0.00352423,0;SGB=-0.379885;RPBZ=1.67751;MQBZ=0;MQSBZ=0;BQBZ=-1.7355;SCBZ=0.856937;MQ0F=0 PL:AD 0,255,255,255,255,255:93,1,0 000000F 503 . G <*> 0 . DP=98;I16=54,40,0,0,3540,140610,0,0,5640,338400,0,0,2108,51206,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:94,0 000000F 504 . T C,A,<*> 0 . DP=102;I16=53,42,1,1,3464,137680,20,208,5700,342000,120,7200,2099,50913,25,625;QS=0.994259,0.00344432,0.00229621,0;VDB=0.92;SGB=-0.453602;RPBZ=0.0126977;MQBZ=0;MQSBZ=0;BQBZ=-2.43319;SCBZ=0.512446;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:95,1,1,0 000000F 505 . G <*> 0 . DP=102;I16=54,43,0,0,3640,144678,0,0,5820,349200,0,0,2141,51803,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 506 . C G,<*> 0 . DP=103;I16=54,43,0,1,3621,145273,12,144,5820,349200,60,3600,2138,51502,25,625;QS=0.996697,0.00330306,0;SGB=-0.379885;RPBZ=0.194473;MQBZ=0;MQSBZ=0;BQBZ=-1.75415;SCBZ=-1.07827;MQ0F=0 PL:AD 0,255,255,255,255,255:97,1,0 000000F 507 . T <*> 0 . DP=103;I16=54,44,0,0,3520,139202,0,0,5880,352800,0,0,2181,52471,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:98,0 000000F 508 . C T,<*> 0 . DP=103;I16=54,43,0,1,3476,137498,12,144,5820,349200,60,3600,2174,52226,25,625;QS=0.99656,0.00344037,0;SGB=-0.379885;RPBZ=0.265217;MQBZ=0;MQSBZ=0;BQBZ=-1.63996;SCBZ=-1.07818;MQ0F=0 PL:AD 0,255,255,255,255,255:97,1,0 000000F 509 . C <*> 0 . DP=103;I16=54,44,0,0,3580,142206,0,0,5880,352800,0,0,2217,53267,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:98,0 000000F 510 . C A,G,<*> 0 . DP=106;I16=54,43,1,2,3646,145190,42,692,5820,349200,180,10800,2189,52645,67,1515;QS=0.988612,0.00921909,0.0021692,0;VDB=0.401962;SGB=-0.511536;RPBZ=-0.707412;MQBZ=0;MQSBZ=0;BQBZ=-3.02794;SCBZ=-0.99293;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:97,2,1,0 000000F 511 . T A,<*> 0 . DP=107;I16=55,45,0,1,3663,144413,12,144,6000,360000,60,3600,2251,54067,25,625;QS=0.996735,0.00326531,0;SGB=-0.379885;RPBZ=-0.0343102;MQBZ=0;MQSBZ=0;BQBZ=-1.71065;SCBZ=-1.08137;MQ0F=0 PL:AD 0,255,255,255,255,255:100,1,0 000000F 512 . C A,G,<*> 0 . DP=107;I16=55,43,1,3,3657,146609,54,836,5880,352800,240,14400,2238,53902,83,1939;QS=0.985449,0.0123956,0.00215575,0;VDB=0.681156;SGB=-0.556411;RPBZ=-0.465574;MQBZ=0;MQSBZ=0;BQBZ=-3.45917;SCBZ=-0.667699;MQ0F=0 PL:AD 0,248,255,255,255,255,255,255,255,255:98,3,1,0 000000F 513 . T G,<*> 0 . DP=108;I16=56,46,0,1,3774,150038,7,49,6120,367200,60,3600,2340,56352,0,0;QS=0.998149,0.00185136,0;SGB=-0.379885;RPBZ=-1.71577;MQBZ=0;MQSBZ=0;BQBZ=-1.90666;SCBZ=-1.07835;MQ0F=0 PL:AD 0,255,255,255,255,255:102,1,0 000000F 514 . G T,<*> 0 . DP=110;I16=56,47,1,1,3763,148539,20,208,6180,370800,120,7200,2348,56422,25,625;QS=0.994713,0.00528681,0;VDB=0.44;SGB=-0.453602;RPBZ=-1.58286;MQBZ=0;MQSBZ=0;BQBZ=-2.48498;SCBZ=0.0121282;MQ0F=0 PL:AD 0,255,255,255,255,255:103,2,0 000000F 515 . C G,<*> 0 . DP=110;I16=57,47,0,1,3848,153002,12,144,6240,374400,60,3600,2367,56887,25,625;QS=0.996891,0.00310881,0;SGB=-0.379885;RPBZ=0.263997;MQBZ=0;MQSBZ=0;BQBZ=-1.75323;SCBZ=-1.07538;MQ0F=0 PL:AD 0,255,255,255,255,255:104,1,0 000000F 516 . G T,<*> 0 . DP=111;I16=57,48,0,1,3969,158573,12,144,6300,378000,60,3600,2411,58015,0,0;QS=0.996986,0.00301432,0;SGB=-0.379885;RPBZ=-1.71626;MQBZ=0;MQSBZ=0;BQBZ=-1.8341;SCBZ=-1.06697;MQ0F=0 PL:AD 0,255,255,255,255,255:105,1,0 000000F 517 . T C,<*> 0 . DP=112;I16=56,50,1,0,3850,151946,12,144,6360,381600,60,3600,2408,58016,21,441;QS=0.996893,0.0031072,0;SGB=-0.379885;RPBZ=-0.7772;MQBZ=0;MQSBZ=0;BQBZ=-1.67048;SCBZ=0.856997;MQ0F=0 PL:AD 0,255,255,255,255,255:106,1,0 000000F 518 . G <*> 0 . DP=115;I16=59,50,0,0,3977,155237,0,0,6540,392400,0,0,2447,58891,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 519 . C A,<*> 0 . DP=116;I16=60,49,0,1,4018,159736,12,144,6540,392400,60,3600,2443,58747,25,625;QS=0.997022,0.00297767,0;SGB=-0.379885;RPBZ=0.110257;MQBZ=0;MQSBZ=0;BQBZ=-1.72465;SCBZ=-1.03419;MQ0F=0 PL:AD 0,255,255,255,255,255:109,1,0 000000F 520 . T G,C,A 0 . DP=116;I16=59,48,1,2,4046,162680,48,1152,6420,385200,180,10800,2436,58644,53,1259;QS=0.988276,0.00781632,0.00195408,0.00195408;VDB=0.913952;SGB=-0.511536;RPBZ=0.578224;MQBZ=0;MQSBZ=0;BQBZ=-2.88822;SCBZ=-0.373153;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:107,1,1,1 000000F 521 . G A,T,<*> 0 . DP=118;I16=61,48,1,2,4131,166701,36,432,6540,392400,180,10800,2454,59246,53,1089;QS=0.991361,0.00575954,0.00287977,0;VDB=0.251321;SGB=-0.511536;RPBZ=-1.60419;MQBZ=0;MQSBZ=0;BQBZ=-3.05428;SCBZ=-0.836529;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:109,2,1,0 000000F 522 . G <*> 0 . DP=118;I16=62,50,0,0,4076,161128,0,0,6720,403200,0,0,2525,60719,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:112,0 000000F 523 . C A,<*> 0 . DP=119;I16=63,49,0,1,4174,166860,12,144,6720,403200,60,3600,2518,60530,25,625;QS=0.997133,0.0028667,0;SGB=-0.379885;RPBZ=-0.13799;MQBZ=0;MQSBZ=0;BQBZ=-1.80506;SCBZ=-1.02482;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 524 . T G,<*> 0 . DP=119;I16=62,50,1,0,4191,166163,27,729,6720,403200,60,3600,2537,61019,25,625;QS=0.993599,0.00640114,0;SGB=-0.379885;RPBZ=-0.82791;MQBZ=0;MQSBZ=0;BQBZ=-1.39926;SCBZ=0.0480382;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 525 . A C,G,<*> 0 . DP=119;I16=62,48,1,2,4098,163296,36,432,6600,396000,180,10800,2509,60447,71,1691;QS=0.991292,0.00580552,0.00290276,0;VDB=0.199299;SGB=-0.511536;RPBZ=-1.60781;MQBZ=0;MQSBZ=0;BQBZ=-2.97339;SCBZ=1.45142;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:110,2,1,0 000000F 526 . T A,<*> 0 . DP=120;I16=63,49,0,1,4180,166064,12,144,6720,403200,60,3600,2570,61910,25,625;QS=0.997137,0.0028626,0;SGB=-0.379885;RPBZ=-1.2266;MQBZ=0;MQSBZ=0;BQBZ=-1.74833;SCBZ=0.367327;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 527 . C G,A,<*> 0 . DP=120;I16=62,49,1,1,4246,172572,24,288,6660,399600,120,7200,2557,61573,48,1154;QS=0.994379,0.0028103,0.0028103,0;VDB=0.18;SGB=-0.453602;RPBZ=-1.28504;MQBZ=0;MQSBZ=0;BQBZ=-2.51884;SCBZ=1.10043;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:111,1,1,0 000000F 528 . A G,<*> 0 . DP=121;I16=62,51,1,0,4295,173733,12,144,6780,406800,60,3600,2588,62236,25,625;QS=0.997214,0.00278616,0;SGB=-0.379885;RPBZ=-0.805477;MQBZ=0;MQSBZ=0;BQBZ=-1.82642;SCBZ=0.0634184;MQ0F=0 PL:AD 0,255,255,255,255,255:113,1,0 000000F 529 . T C,<*> 0 . DP=123;I16=65,50,0,1,4363,176845,8,64,6900,414000,60,3600,2639,63305,25,625;QS=0.99817,0.00183024,0;SGB=-0.379885;RPBZ=-1.04546;MQBZ=0;MQSBZ=0;BQBZ=-1.9592;SCBZ=-1.04156;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 530 . G <*> 0 . DP=123;I16=65,51,0,0,4357,176035,0,0,6960,417600,0,0,2672,64088,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:116,0 000000F 531 . T A,G,<*> 0 . DP=123;I16=63,49,2,2,4199,169729,48,576,6720,403200,240,14400,2579,61741,100,2500;QS=0.988698,0.00847657,0.00282552,0;VDB=0.0550934;SGB=-0.556411;RPBZ=-0.650816;MQBZ=0;MQSBZ=0;BQBZ=-3.46139;SCBZ=-0.463641;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:112,3,1,0 000000F 532 . C A,G,<*> 0 . DP=124;I16=65,49,0,3,4352,176182,36,432,6840,410400,180,10800,2640,63492,45,897;QS=0.991796,0.00546946,0.00273473,0;VDB=0.588406;SGB=-0.511536;RPBZ=-1.58686;MQBZ=0;MQSBZ=0;BQBZ=-3.10955;SCBZ=-1.82952;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:114,2,1,0 000000F 533 . A <*> 0 . DP=124;I16=65,52,0,0,4235,168199,0,0,7020,421200,0,0,2692,64582,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:117,0 000000F 534 . G A,<*> 0 . DP=124;I16=65,51,0,1,4319,173543,12,144,6960,417600,60,3600,2677,64331,21,441;QS=0.997229,0.00277072,0;SGB=-0.379885;RPBZ=-1.3327;MQBZ=0;MQSBZ=0;BQBZ=-1.72023;SCBZ=-1.04702;MQ0F=0 PL:AD 0,255,255,255,255,255:116,1,0 000000F 535 . G A,<*> 0 . DP=125;I16=65,52,0,1,4309,171791,12,144,7020,421200,60,3600,2679,64385,25,625;QS=0.997223,0.00277713,0;SGB=-0.379885;RPBZ=-1.10121;MQBZ=0;MQSBZ=0;BQBZ=-1.74874;SCBZ=0.0762649;MQ0F=0 PL:AD 0,255,255,255,255,255:117,1,0 000000F 536 . T G,A,<*> 0 . DP=125;I16=65,51,0,2,4274,171298,24,288,6960,417600,120,7200,2661,64041,48,1154;QS=0.994416,0.002792,0.002792,0;VDB=0.1;SGB=-0.453602;RPBZ=-1.74128;MQBZ=0;MQSBZ=0;BQBZ=-2.39373;SCBZ=-0.693187;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:116,1,1,0 000000F 537 . A <*> 0 . DP=125;I16=65,53,0,0,4390,175290,0,0,7080,424800,0,0,2713,65375,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:118,0 000000F 537 . AC A 0 . INDEL;IDV=60;IMF=0.48;DP=125;I16=36,26,30,27,2480,99200,2280,91200,3720,223200,3420,205200,1433,34549,1298,31150;QS=0.263673,0.736327;VDB=0.383756;SGB=-0.693147;RPBZ=-0.543708;MQBZ=0;MQSBZ=0;BQBZ=-2.39373;SCBZ=0.641853;MQ0F=0 PL:AD 255,0,28:62,57 000000F 538 . C <*> 0 . DP=65;I16=36,26,0,0,2195,86349,0,0,3720,223200,0,0,1432,34600,0,0;QS=1,0;MQ0F=0 PL:AD 0,187,255:62,0 000000F 538 . CT C 0 . INDEL;IDV=64;IMF=0.512;DP=125;I16=30,26,36,25,2240,89600,2440,97600,3360,201600,3660,219600,1277,30663,1380,33214;QS=0.22136,0.77864;VDB=0.00357075;SGB=-0.693147;RPBZ=0.242079;MQBZ=0;MQSBZ=0;BQBZ=-2.39373;SCBZ=-0.994262;MQ0F=0 PL:AD 255,0,28:56,61 000000F 539 . T <*> 0 . DP=60;I16=29,26,0,0,2120,86238,0,0,3300,198000,0,0,1260,30374,0,0;QS=1,0;MQ0F=0 PL:AD 0,166,255:55,0 000000F 540 . G <*> 0 . DP=124;I16=64,53,0,0,4130,161310,0,0,7020,421200,0,0,2703,65511,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:117,0 000000F 541 . G <*> 0 . DP=124;I16=64,53,0,0,4143,160525,0,0,7020,421200,0,0,2705,65703,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:117,0 000000F 542 . T G,A,<*> 0 . DP=124;I16=63,52,1,1,4035,156631,24,288,6900,414000,120,7200,2657,64685,50,1250;QS=0.994087,0.00295639,0.00295639,0;VDB=0.26;SGB=-0.453602;RPBZ=-1.44078;MQBZ=0;MQSBZ=0;BQBZ=-2.25702;SCBZ=-0.906022;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:115,1,1,0 000000F 543 . C G,A,<*> 0 . DP=122;I16=62,53,1,1,4006,154170,24,288,6900,414000,120,7200,2673,65063,50,1250;QS=0.994045,0.00297767,0.00297767,0;VDB=0.22;SGB=-0.453602;RPBZ=-0.483734;MQBZ=0;MQSBZ=0;BQBZ=-2.21926;SCBZ=0.31726;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:115,1,1,0 000000F 544 . T A,<*> 0 . DP=121;I16=62,53,0,1,4151,162625,12,144,6900,414000,60,3600,2697,65733,25,625;QS=0.997117,0.00288254,0;SGB=-0.379885;RPBZ=0.238977;MQBZ=0;MQSBZ=0;BQBZ=-1.67238;SCBZ=-1.05505;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 545 . G A,<*> 0 . DP=121;I16=62,53,0,1,4078,158586,12,144,6900,414000,60,3600,2710,66228,8,64;QS=0.997066,0.00293399,0;SGB=-0.379885;RPBZ=1.6131;MQBZ=0;MQSBZ=0;BQBZ=-1.61213;SCBZ=-1.05503;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 546 . G A,<*> 0 . DP=121;I16=62,53,0,1,4230,164790,12,144,6900,414000,60,3600,2689,65637,25,625;QS=0.997171,0.00282885,0;SGB=-0.379885;RPBZ=-0.97077;MQBZ=0;MQSBZ=0;BQBZ=-1.77555;SCBZ=-1.0549;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 547 . A C,<*> 0 . DP=119;I16=62,51,0,1,4105,158737,12,144,6780,406800,60,3600,2686,65592,25,625;QS=0.997085,0.00291474,0;SGB=-0.379885;RPBZ=-0.896646;MQBZ=0;MQSBZ=0;BQBZ=-1.70779;SCBZ=0.0314879;MQ0F=0 PL:AD 0,255,255,255,255,255:113,1,0 000000F 548 . C G,<*> 0 . DP=119;I16=62,51,0,1,4014,154686,12,144,6780,406800,60,3600,2681,65479,25,625;QS=0.997019,0.00298063,0;SGB=-0.379885;RPBZ=-0.896728;MQBZ=0;MQSBZ=0;BQBZ=-1.67128;SCBZ=0.0314876;MQ0F=0 PL:AD 0,255,255,255,255,255:113,1,0 000000F 549 . C A,<*> 0 . DP=117;I16=33,29,29,22,2214,83510,1893,75363,3720,223200,3060,183600,1463,35977,1212,29370;QS=0.53908,0.46092,0;VDB=0.0978768;SGB=-0.693147;RPBZ=-0.600202;MQBZ=0;MQSBZ=0;BQBZ=1.17837;SCBZ=0.928426;MQ0F=0 PL:AD 255,0,255,255,255,255:62,51,0 000000F 550 . G T,<*> 0 . DP=117;I16=62,50,0,1,4113,161301,22,484,6720,403200,60,3600,2641,64473,25,625;QS=0.99468,0.00532044,0;SGB=-0.379885;RPBZ=-0.950536;MQBZ=0;MQSBZ=0;BQBZ=-1.55326;SCBZ=-1.07862;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 551 . G T,A,<*> 0 . DP=116;I16=60,50,1,1,4131,164089,24,288,6600,396000,120,7200,2607,63583,50,1250;QS=0.994224,0.00288809,0.00288809,0;VDB=0.32;SGB=-0.453602;RPBZ=-1.01088;MQBZ=0;MQSBZ=0;BQBZ=-2.59034;SCBZ=0.329971;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:110,1,1,0 000000F 552 . A C,<*> 0 . DP=116;I16=60,50,1,1,3927,151331,24,288,6600,396000,120,7200,2598,63352,50,1250;QS=0.993926,0.00607441,0;VDB=0.1;SGB=-0.453602;RPBZ=-1.12079;MQBZ=0;MQSBZ=0;BQBZ=-2.37929;SCBZ=-0.136538;MQ0F=0 PL:AD 0,255,255,255,255,255:110,2,0 000000F 553 . G T,<*> 0 . DP=116;I16=60,51,1,0,4046,158108,12,144,6660,399600,60,3600,2613,63729,25,625;QS=0.997043,0.00295712,0;SGB=-0.379885;RPBZ=-0.35579;MQBZ=0;MQSBZ=0;BQBZ=-1.77886;SCBZ=0.688792;MQ0F=0 PL:AD 0,255,255,255,255,255:111,1,0 000000F 554 . A <*> 0 . DP=113;I16=60,50,0,0,4046,159278,0,0,6600,396000,0,0,2629,64087,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:110,0 000000F 555 . G <*> 0 . DP=112;I16=60,49,0,0,4016,156988,0,0,6540,392400,0,0,2600,63438,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 556 . A <*> 0 . DP=112;I16=60,49,0,0,3915,151463,0,0,6540,392400,0,0,2588,63068,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 557 . A <*> 0 . DP=112;I16=60,49,0,0,3957,151889,0,0,6540,392400,0,0,2575,62681,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 558 . A G,<*> 0 . DP=112;I16=60,47,0,2,3726,140280,24,288,6420,385200,120,7200,2510,60980,50,1250;QS=0.9936,0.0064,0;VDB=0.22;SGB=-0.453602;RPBZ=-1.14043;MQBZ=0;MQSBZ=0;BQBZ=-2.29525;SCBZ=-0.444037;MQ0F=0 PL:AD 0,255,255,255,255,255:107,2,0 000000F 559 . C T,<*> 0 . DP=112;I16=59,49,1,0,3985,155617,12,144,6480,388800,60,3600,2518,61092,25,625;QS=0.996998,0.00300225,0;SGB=-0.379885;RPBZ=0.731168;MQBZ=0;MQSBZ=0;BQBZ=-1.78272;SCBZ=-1.08527;MQ0F=0 PL:AD 0,255,255,255,255,255:108,1,0 000000F 560 . T <*> 0 . DP=110;I16=59,48,0,0,3896,150870,0,0,6420,385200,0,0,2507,60841,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:107,0 000000F 561 . G <*> 0 . DP=110;I16=59,48,0,0,3921,153367,0,0,6420,385200,0,0,2492,60440,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:107,0 000000F 562 . T C,A,<*> 0 . DP=110;I16=58,47,1,1,3748,143542,24,288,6300,378000,120,7200,2425,58723,50,1250;QS=0.993637,0.00318134,0.00318134,0;VDB=0.32;SGB=-0.453602;RPBZ=1.03535;MQBZ=0;MQSBZ=0;BQBZ=-2.35872;SCBZ=-0.452888;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:105,1,1,0 000000F 563 . G A,<*> 0 . DP=109;I16=59,45,0,2,3881,153011,24,288,6240,374400,120,7200,2384,57712,50,1250;QS=0.993854,0.00614597,0;VDB=0.06;SGB=-0.453602;RPBZ=-1.81161;MQBZ=0;MQSBZ=0;BQBZ=-2.59069;SCBZ=-0.927311;MQ0F=0 PL:AD 0,255,255,255,255,255:104,2,0 000000F 564 . G <*> 0 . DP=109;I16=59,47,0,0,3954,155218,0,0,6360,381600,0,0,2417,58561,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:106,0 000000F 565 . A G,<*> 0 . DP=108;I16=59,44,0,2,3818,150006,24,288,6180,370800,120,7200,2351,56943,50,1250;QS=0.993753,0.00624675,0;VDB=0.52;SGB=-0.453602;RPBZ=-0.0703536;MQBZ=0;MQSBZ=0;BQBZ=-2.43017;SCBZ=-0.752998;MQ0F=0 PL:AD 0,255,255,255,255,255:103,2,0 000000F 566 . T <*> 0 . DP=108;I16=59,46,0,0,3981,157549,0,0,6300,378000,0,0,2384,57808,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:105,0 000000F 567 . G T,C,<*> 0 . DP=108;I16=57,46,2,0,3847,151871,20,208,6180,370800,120,7200,2318,56254,48,1154;QS=0.994828,0.00310318,0.00206879,0;VDB=0.7;SGB=-0.453602;RPBZ=0.128964;MQBZ=0;MQSBZ=0;BQBZ=-2.74966;SCBZ=-0.146119;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:103,1,1,0 000000F 568 . T C,<*> 0 . DP=106;I16=56,47,1,0,3763,145559,8,64,6180,370800,60,3600,2349,56993,25,625;QS=0.997879,0.00212145,0;SGB=-0.379885;RPBZ=0.983018;MQBZ=0;MQSBZ=0;BQBZ=-1.93576;SCBZ=-1.05631;MQ0F=0 PL:AD 0,255,255,255,255,255:103,1,0 000000F 569 . C G,A,<*> 0 . DP=104;I16=55,45,0,2,3734,146948,24,288,6000,360000,120,7200,2309,55985,50,1250;QS=0.993614,0.00319319,0.00319319,0;VDB=0.58;SGB=-0.453602;RPBZ=-0.543243;MQBZ=0;MQSBZ=0;BQBZ=-2.54989;SCBZ=-1.48352;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:100,1,1,0 000000F 570 . T <*> 0 . DP=104;I16=55,47,0,0,3862,151566,0,0,6120,367200,0,0,2342,56784,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:102,0 000000F 571 . G <*> 0 . DP=104;I16=55,47,0,0,3733,145003,0,0,6120,367200,0,0,2325,56367,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:102,0 000000F 572 . T A,G,<*> 0 . DP=103;I16=53,46,1,1,3664,142548,34,628,5940,356400,120,7200,2259,54733,50,1250;QS=0.990806,0.00594916,0.003245,0;VDB=0.22;SGB=-0.453602;RPBZ=0.219457;MQBZ=0;MQSBZ=0;BQBZ=-2.44659;SCBZ=0.216127;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:99,1,1,0 000000F 573 . C G,<*> 0 . DP=103;I16=54,46,0,1,3749,146645,12,144,6000,360000,60,3600,2267,54957,25,625;QS=0.996809,0.00319064,0;SGB=-0.379885;RPBZ=-0.428856;MQBZ=0;MQSBZ=0;BQBZ=-1.85387;SCBZ=-1.03794;MQ0F=0 PL:AD 0,255,255,255,255,255:100,1,0 000000F 574 . A <*> 0 . DP=102;I16=54,46,0,0,3671,141999,0,0,6000,360000,0,0,2275,55165,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:100,0 000000F 575 . A <*> 0 . DP=101;I16=53,46,0,0,3653,142115,0,0,5940,356400,0,0,2259,54781,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:99,0 000000F 576 . C <*> 0 . DP=99;I16=52,45,0,0,3665,144129,0,0,5820,349200,0,0,2229,54203,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 577 . A <*> 0 . DP=99;I16=52,45,0,0,3533,136769,0,0,5820,349200,0,0,2212,53762,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 578 . C <*> 0 . DP=99;I16=52,45,0,0,3593,140361,0,0,5820,349200,0,0,2189,53061,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 579 . A <*> 0 . DP=98;I16=51,45,0,0,3516,137036,0,0,5760,345600,0,0,2166,52356,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:96,0 000000F 580 . A <*> 0 . DP=98;I16=51,45,0,0,3569,139629,0,0,5760,345600,0,0,2141,51599,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:96,0 000000F 581 . C <*> 0 . DP=95;I16=49,44,0,0,3512,137782,0,0,5580,334800,0,0,2096,50392,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:93,0 000000F 582 . A <*> 0 . DP=94;I16=49,43,0,0,3411,135315,0,0,5520,331200,0,0,2073,49673,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:92,0 000000F 583 . G C,<*> 0 . DP=90;I16=46,41,1,0,3292,129550,12,144,5220,313200,60,3600,1985,47479,25,625;QS=0.996368,0.00363196,0;SGB=-0.379885;RPBZ=0.334737;MQBZ=0;MQSBZ=0;BQBZ=-1.89321;SCBZ=-1.01118;MQ0F=0 PL:AD 0,245,255,255,255,255:87,1,0 000000F 584 . A <*> 0 . DP=87;I16=45,40,0,0,3152,123280,0,0,5100,306000,0,0,1940,46204,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 585 . A <*> 0 . DP=88;I16=44,40,0,0,3202,127432,0,0,5040,302400,0,0,1914,45520,0,0;QS=1,0;MQ0F=0 PL:AD 0,253,255:84,0 000000F 586 . A G,<*> 0 . DP=88;I16=43,40,1,0,2964,114852,12,144,4980,298800,60,3600,1875,44509,16,256;QS=0.995968,0.00403226,0;SGB=-0.379885;RPBZ=0.866495;MQBZ=0;MQSBZ=0;BQBZ=-1.73561;SCBZ=1.14098;MQ0F=0 PL:AD 0,234,255,250,255,255:83,1,0 000000F 587 . A C,<*> 0 . DP=88;I16=45,40,0,1,2997,115249,12,144,5100,306000,60,3600,1891,44583,25,625;QS=0.996012,0.00398804,0;SGB=-0.379885;RPBZ=-0.584321;MQBZ=0;MQSBZ=0;BQBZ=-1.64438;SCBZ=0.548806;MQ0F=0 PL:AD 0,240,255,255,255,255:85,1,0 000000F 588 . A <*> 0 . DP=87;I16=45,40,0,0,2971,113817,0,0,5100,306000,0,0,1891,44401,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 589 . G A,<*> 0 . DP=87;I16=44,40,1,0,3059,117323,12,144,5040,302400,60,3600,1840,42970,25,625;QS=0.996092,0.00390752,0;SGB=-0.379885;RPBZ=0.550542;MQBZ=0;MQSBZ=0;BQBZ=-1.79452;SCBZ=1.68471;MQ0F=0 PL:AD 0,237,255,253,255,255:84,1,0 000000F 590 . T <*> 0 . DP=87;I16=45,40,0,0,3019,114421,0,0,5100,306000,0,0,1839,42841,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 591 . G C,<*> 0 . DP=86;I16=43,40,1,0,3033,117015,12,144,4980,298800,60,3600,1807,42121,3,9;QS=0.996059,0.00394089,0;SGB=-0.379885;RPBZ=1.67089;MQBZ=0;MQSBZ=0;BQBZ=-1.80181;SCBZ=-1.01597;MQ0F=0 PL:AD 0,234,255,250,255,255:83,1,0 000000F 592 . A C,<*> 0 . DP=85;I16=44,38,0,2,2821,106231,24,288,4920,295200,120,7200,1748,40690,36,746;QS=0.991564,0.00843585,0;VDB=0.5;SGB=-0.453602;RPBZ=0.484389;MQBZ=0;MQSBZ=0;BQBZ=-2.1998;SCBZ=-0.0922779;MQ0F=0 PL:AD 0,217,255,247,255,255:82,2,0 000000F 593 . C G,A,<*> 0 . DP=84;I16=42,39,1,1,2912,110366,24,288,4860,291600,120,7200,1709,39543,50,1250;QS=0.991826,0.00408719,0.00408719,0;VDB=0.36;SGB=-0.453602;RPBZ=-0.0891287;MQBZ=0;MQSBZ=0;BQBZ=-2.57106;SCBZ=-0.108692;MQ0F=0 PL:AD 0,228,255,228,255,255,244,255,255,255:81,1,1,0 000000F 594 . T <*> 0 . DP=84;I16=43,40,0,0,2911,110919,0,0,4980,298800,0,0,1733,40151,0,0;QS=1,0;MQ0F=0 PL:AD 0,250,255:83,0 000000F 595 . G <*> 0 . DP=82;I16=42,39,0,0,2849,108157,0,0,4860,291600,0,0,1681,38837,0,0;QS=1,0;MQ0F=0 PL:AD 0,244,255:81,0 000000F 596 . A C,<*> 0 . DP=81;I16=42,37,0,1,2846,108902,12,144,4740,284400,60,3600,1613,37303,25,625;QS=0.995801,0.00419874,0;SGB=-0.379885;RPBZ=-0.9748;MQBZ=0;MQSBZ=0;BQBZ=-1.73819;SCBZ=0.250526;MQ0F=0 PL:AD 0,222,255,238,255,255:79,1,0 000000F 597 . T G,<*> 0 . DP=80;I16=42,36,0,1,2742,102116,12,144,4680,280800,60,3600,1574,36614,15,225;QS=0.995643,0.0043573,0;SGB=-0.379885;RPBZ=0.833621;MQBZ=0;MQSBZ=0;BQBZ=-1.70797;SCBZ=0.254296;MQ0F=0 PL:AD 0,219,255,235,255,255:78,1,0 000000F 598 . T <*> 0 . DP=79;I16=41,37,0,0,2839,109553,0,0,4680,280800,0,0,1562,36238,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 599 . A <*> 0 . DP=77;I16=40,36,0,0,2770,106710,0,0,4560,273600,0,0,1528,35518,0,0;QS=1,0;MQ0F=0 PL:AD 0,229,255:76,0 000000F 600 . G <*> 0 . DP=77;I16=40,36,0,0,2714,103152,0,0,4560,273600,0,0,1498,34792,0,0;QS=1,0;MQ0F=0 PL:AD 0,229,255:76,0 000000F 601 . T G,C,<*> 0 . DP=77;I16=39,35,1,1,2583,97801,24,288,4440,266400,120,7200,1417,32827,50,1250;QS=0.990798,0.00460123,0.00460123,0;VDB=0.1;SGB=-0.453602;RPBZ=-0.795612;MQBZ=0;MQSBZ=0;BQBZ=-2.28816;SCBZ=0.0680273;MQ0F=0 PL:AD 0,207,255,207,255,255,223,255,255,255:74,1,1,0 000000F 602 . T A,C,<*> 0 . DP=74;I16=37,33,1,2,2416,90472,61,1657,4200,252000,180,10800,1357,31631,60,1350;QS=0.975373,0.019782,0.00484457,0;VDB=0.568985;SGB=-0.511536;RPBZ=0.333732;MQBZ=0;MQSBZ=0;BQBZ=-2.13242;SCBZ=0.845379;MQ0F=0 PL:AD 0,164,255,195,255,255,211,255,255,255:70,2,1,0 000000F 603 . A C,<*> 0 . DP=68;I16=35,30,1,0,2312,88408,12,144,3900,234000,60,3600,1347,31297,25,625;QS=0.994837,0.00516351,0;SGB=-0.379885;RPBZ=-0.131301;MQBZ=0;MQSBZ=0;BQBZ=-1.66952;SCBZ=-1.04349;MQ0F=0 PL:AD 0,180,255,196,255,255:65,1,0 000000F 604 . G <*> 0 . DP=67;I16=36,30,0,0,2403,93039,0,0,3960,237600,0,0,1349,31351,0,0;QS=1,0;MQ0F=0 PL:AD 0,199,255:66,0 000000F 605 . A G,<*> 0 . DP=66;I16=35,28,1,1,2254,85780,24,288,3780,226800,120,7200,1292,30038,33,689;QS=0.989464,0.0105356,0;VDB=0.36;SGB=-0.453602;RPBZ=0.589131;MQBZ=0;MQSBZ=0;BQBZ=-2.37279;SCBZ=1.62638;MQ0F=0 PL:AD 0,162,255,190,255,255:63,2,0 000000F 606 . T G,<*> 0 . DP=65;I16=34,29,1,0,2247,87073,22,484,3780,226800,60,3600,1287,29883,13,169;QS=0.990304,0.0096959,0;SGB=-0.379885;RPBZ=1.00206;MQBZ=0;MQSBZ=0;BQBZ=-1.38823;SCBZ=-1.04683;MQ0F=0 PL:AD 0,170,255,190,255,255:63,1,0 000000F 607 . G <*> 0 . DP=64;I16=35,28,0,0,2255,86451,0,0,3780,226800,0,0,1255,29027,0,0;QS=1,0;MQ0F=0 PL:AD 0,190,255:63,0 000000F 608 . T G,<*> 0 . DP=62;I16=33,27,1,0,2177,84023,8,64,3600,216000,60,3600,1182,27240,25,625;QS=0.996339,0.00366133,0;SGB=-0.379885;RPBZ=0.0852552;MQBZ=0;MQSBZ=0;BQBZ=-1.89659;SCBZ=-1.04111;MQ0F=0 PL:AD 0,166,255,181,255,255:60,1,0 000000F 609 . A G,<*> 0 . DP=60;I16=33,25,0,1,2036,77468,12,144,3480,208800,60,3600,1139,26307,25,625;QS=0.994141,0.00585938,0;SGB=-0.379885;RPBZ=-0.0881423;MQBZ=0;MQSBZ=0;BQBZ=-1.68674;SCBZ=1.23654;MQ0F=0 PL:AD 0,160,255,175,255,255:58,1,0 000000F 610 . A <*> 0 . DP=59;I16=33,25,0,0,2025,77505,0,0,3480,208800,0,0,1144,26524,0,0;QS=1,0;MQ0F=0 PL:AD 0,175,255:58,0 000000F 611 . C T,<*> 0 . DP=55;I16=14,12,16,12,990,39320,1009,38281,1560,93600,1680,100800,576,13946,550,12206;QS=0.495248,0.504752,0;VDB=1.84196e-06;SGB=-0.693054;RPBZ=1.75927;MQBZ=0;MQSBZ=0;BQBZ=-0.270305;SCBZ=-0.614376;MQ0F=0 PL:AD 255,0,255,255,255,255:26,28,0 000000F 612 . T <*> 0 . DP=54;I16=29,24,0,0,1898,72790,0,0,3180,190800,0,0,1111,25815,0,0;QS=1,0;MQ0F=0 PL:AD 0,160,255:53,0 000000F 613 . A G,C,<*> 0 . DP=54;I16=27,24,2,0,1946,77058,24,288,3060,183600,120,7200,1046,24258,50,1250;QS=0.987817,0.00609137,0.00609137,0;VDB=0.06;SGB=-0.453602;RPBZ=0.537207;MQBZ=0;MQSBZ=0;BQBZ=-2.67554;SCBZ=0.495445;MQ0F=0 PL:AD 0,139,255,139,255,255,154,255,255,255:51,1,1,0 000000F 614 . A C,<*> 0 . DP=53;I16=28,23,0,1,1870,73000,12,144,3060,183600,60,3600,1054,24458,25,625;QS=0.993624,0.0063762,0;SGB=-0.379885;RPBZ=0.033359;MQBZ=0;MQSBZ=0;BQBZ=-1.88;SCBZ=1.24225;MQ0F=0 PL:AD 0,139,255,154,255,255:51,1,0 000000F 615 . T <*> 0 . DP=53;I16=28,24,0,0,1924,74686,0,0,3120,187200,0,0,1061,24643,0,0;QS=1,0;MQ0F=0 PL:AD 0,157,255:52,0 000000F 616 . T G,<*> 0 . DP=53;I16=28,23,0,1,1815,69225,12,144,3060,183600,60,3600,1017,23565,25,625;QS=0.993432,0.00656814,0;SGB=-0.379885;RPBZ=-0.833529;MQBZ=0;MQSBZ=0;BQBZ=-1.66586;SCBZ=0.352496;MQ0F=0 PL:AD 0,139,255,154,255,255:51,1,0 000000F 617 . T <*> 0 . DP=52;I16=27,24,0,0,1844,70962,0,0,3060,183600,0,0,1024,23774,0,0;QS=1,0;MQ0F=0 PL:AD 0,154,255:51,0 000000F 618 . C <*> 0 . DP=52;I16=27,24,0,0,1782,67390,0,0,3060,183600,0,0,1005,23345,0,0;QS=1,0;MQ0F=0 PL:AD 0,154,255:51,0 000000F 619 . A C,<*> 0 . DP=52;I16=26,24,1,0,1756,66842,12,144,3000,180000,60,3600,961,22329,25,625;QS=0.993213,0.00678733,0;SGB=-0.379885;RPBZ=0.612053;MQBZ=0;MQSBZ=0;BQBZ=-1.58836;SCBZ=1.65684;MQ0F=0 PL:AD 0,136,255,151,255,255:50,1,0 000000F 620 . A <*> 0 . DP=50;I16=25,24,0,0,1670,63616,0,0,2940,176400,0,0,969,22599,0,0;QS=1,0;MQ0F=0 PL:AD 0,148,255:49,0 000000F 621 . C <*> 0 . DP=49;I16=24,24,0,0,1738,67580,0,0,2880,172800,0,0,953,22277,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 622 . T <*> 0 . DP=47;I16=23,23,0,0,1642,63060,0,0,2760,165600,0,0,921,21681,0,0;QS=1,0;MQ0F=0 PL:AD 0,138,255:46,0 000000F 623 . A G,C,<*> 0 . DP=46;I16=22,21,1,1,1593,61369,24,288,2580,154800,120,7200,862,20368,44,986;QS=0.985158,0.00742115,0.00742115,0;VDB=0.28;SGB=-0.453602;RPBZ=0.110272;MQBZ=0;MQSBZ=0;BQBZ=-2.46441;SCBZ=-0.699329;MQ0F=0 PL:AD 0,116,255,116,255,255,129,255,255,255:43,1,1,0 000000F 624 . T <*> 0 . DP=45;I16=22,22,0,0,1522,57304,0,0,2640,158400,0,0,892,21056,0,0;QS=1,0;MQ0F=0 PL:AD 0,132,255:44,0 000000F 625 . C <*> 0 . DP=43;I16=20,23,0,0,1462,54230,0,0,2580,154800,0,0,905,21409,0,0;QS=1,0;MQ0F=0 PL:AD 0,129,255:43,0 000000F 626 . T A,<*> 0 . DP=42;I16=19,22,0,1,1407,52739,12,144,2460,147600,60,3600,869,20535,25,625;QS=0.991543,0.00845666,0;SGB=-0.379885;RPBZ=0.0826192;MQBZ=0;MQSBZ=0;BQBZ=-1.63079;SCBZ=-0.998652;MQ0F=0 PL:AD 0,110,255,123,255,255:41,1,0 000000F 627 . A <*> 0 . DP=42;I16=19,23,0,0,1458,54660,0,0,2520,151200,0,0,880,20786,0,0;QS=1,0;MQ0F=0 PL:AD 0,126,255:42,0 000000F 628 . G C,<*> 0 . DP=41;I16=17,23,1,0,1491,57863,12,144,2400,144000,60,3600,838,19618,24,576;QS=0.992016,0.00798403,0;SGB=-0.379885;RPBZ=0.296217;MQBZ=0;MQSBZ=0;BQBZ=-1.99912;SCBZ=-0.981384;MQ0F=0 PL:AD 0,107,255,120,255,255:40,1,0 000000F 629 . T <*> 0 . DP=40;I16=18,22,0,0,1452,55272,0,0,2400,144000,0,0,827,19349,0,0;QS=1,0;MQ0F=0 PL:AD 0,120,255:40,0 000000F 630 . C <*> 0 . DP=38;I16=16,22,0,0,1338,50174,0,0,2280,136800,0,0,812,18860,0,0;QS=1,0;MQ0F=0 PL:AD 0,114,255:38,0 000000F 631 . T G,<*> 0 . DP=37;I16=14,22,1,0,1280,48224,32,1024,2160,129600,60,3600,783,18083,11,121;QS=0.97561,0.0243902,0;SGB=-0.379885;RPBZ=1.36088;MQBZ=0;MQSBZ=0;BQBZ=-1.06419;SCBZ=-0.906765;MQ0F=0 PL:AD 0,79,255,108,255,255:36,1,0 000000F 632 . T <*> 0 . DP=36;I16=15,21,0,0,1320,50548,0,0,2160,129600,0,0,761,17359,0,0;QS=1,0;MQ0F=0 PL:AD 0,108,255:36,0 000000F 633 . C A,<*> 0 . DP=35;I16=14,19,0,2,1183,44803,24,288,1980,118800,120,7200,678,15322,47,1109;QS=0.980116,0.019884,0;VDB=0.26;SGB=-0.453602;RPBZ=0.463397;MQBZ=0;MQSBZ=0;BQBZ=-2.3085;SCBZ=1.47371;MQ0F=0 PL:AD 0,76,255,99,255,255:33,2,0 000000F 634 . C <*> 0 . DP=35;I16=14,21,0,0,1290,49572,0,0,2100,126000,0,0,708,15898,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 635 . T <*> 0 . DP=35;I16=14,21,0,0,1242,47888,0,0,2100,126000,0,0,691,15399,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 636 . C T,<*> 0 . DP=34;I16=13,20,1,0,1163,44105,12,144,1980,118800,60,3600,643,14453,16,256;QS=0.989787,0.0102128,0;SGB=-0.379885;RPBZ=0.66524;MQBZ=0;MQSBZ=0;BQBZ=-1.57615;SCBZ=-0.84147;MQ0F=0 PL:AD 0,87,255,99,255,255:33,1,0 000000F 637 . T <*> 0 . DP=33;I16=14,19,0,0,1151,43717,0,0,1980,118800,0,0,627,14033,0,0;QS=1,0;MQ0F=0 PL:AD 0,99,255:33,0 000000F 638 . A <*> 0 . DP=32;I16=13,19,0,0,1113,41153,0,0,1920,115200,0,0,605,13531,0,0;QS=1,0;MQ0F=0 PL:AD 0,96,255:32,0 000000F 639 . A T,<*> 0 . DP=30;I16=13,16,0,1,965,34529,12,144,1740,104400,60,3600,577,12917,13,169;QS=0.987718,0.0122825,0;SGB=-0.379885;RPBZ=0.988773;MQBZ=0;MQSBZ=0;BQBZ=-1.63451;SCBZ=-0.878553;MQ0F=0 PL:AD 0,75,255,87,255,255:29,1,0 000000F 640 . A <*> 0 . DP=29;I16=12,17,0,0,994,36924,0,0,1740,104400,0,0,575,12621,0,0;QS=1,0;MQ0F=0 PL:AD 0,87,255:29,0 000000F 641 . G T,<*> 0 . DP=27;I16=11,15,0,1,869,31995,12,144,1560,93600,60,3600,529,11623,11,121;QS=0.986379,0.0136209,0;SGB=-0.379885;RPBZ=1.35554;MQBZ=0;MQSBZ=0;BQBZ=-1.5086;SCBZ=-0.793551;MQ0F=0 PL:AD 0,66,255,78,255,255:26,1,0 000000F 642 . A C,<*> 0 . DP=26;I16=11,14,0,1,850,31010,22,484,1500,90000,60,3600,504,11078,9,81;QS=0.974771,0.0252294,0;SGB=-0.379885;RPBZ=1.41458;MQBZ=0;MQSBZ=0;BQBZ=-1.18957;SCBZ=0.532911;MQ0F=0 PL:AD 0,56,255,75,255,255:25,1,0 000000F 643 . C <*> 0 . DP=26;I16=11,15,0,0,912,34334,0,0,1560,93600,0,0,499,10747,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 644 . C A,<*> 0 . DP=26;I16=11,14,0,1,869,31707,12,144,1500,90000,60,3600,464,9914,20,400;QS=0.986379,0.0136209,0;SGB=-0.379885;RPBZ=0.268045;MQBZ=0;MQSBZ=0;BQBZ=-1.6731;SCBZ=0.989693;MQ0F=0 PL:AD 0,63,255,75,255,255:25,1,0 000000F 645 . C <*> 0 . DP=26;I16=11,15,0,0,911,33421,0,0,1560,93600,0,0,466,9764,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 646 . C <*> 0 . DP=26;I16=11,15,0,0,850,29718,0,0,1560,93600,0,0,447,9201,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 647 . T C,<*> 0 . DP=26;I16=11,14,0,1,898,34076,12,144,1500,90000,60,3600,423,8651,5,25;QS=0.986813,0.0131868,0;SGB=-0.379885;RPBZ=1.14097;MQBZ=0;MQSBZ=0;BQBZ=-1.57982;SCBZ=-0.760963;MQ0F=0 PL:AD 0,63,255,75,255,255:25,1,0 000000F 648 . A <*> 0 . DP=26;I16=11,15,0,0,870,32110,0,0,1560,93600,0,0,407,8091,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 649 . C <*> 0 . DP=26;I16=11,15,0,0,928,35102,0,0,1560,93600,0,0,386,7548,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 650 . T C,<*> 0 . DP=26;I16=11,14,0,1,897,33867,12,144,1500,90000,60,3600,359,6973,5,25;QS=0.986799,0.0132013,0;SGB=-0.379885;RPBZ=0.874779;MQBZ=0;MQSBZ=0;BQBZ=-1.67266;SCBZ=-0.760963;MQ0F=0 PL:AD 0,63,255,75,255,255:25,1,0 000000F 651 . T <*> 0 . DP=26;I16=11,15,0,0,905,33255,0,0,1560,93600,0,0,342,6492,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 652 . T <*> 0 . DP=25;I16=11,14,0,0,891,32693,0,0,1500,90000,0,0,321,6029,0,0;QS=1,0;MQ0F=0 PL:AD 0,75,255:25,0 000000F 653 . A <*> 0 . DP=21;I16=9,12,0,0,804,31130,0,0,1260,75600,0,0,303,5555,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 654 . A <*> 0 . DP=21;I16=9,12,0,0,659,22061,0,0,1260,75600,0,0,285,5117,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 655 . C <*> 0 . DP=21;I16=9,12,0,0,664,22342,0,0,1260,75600,0,0,266,4666,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 655 . CACAATACAA CACAA 0 . INDEL;IDV=6;IMF=0.285714;DP=21;I16=4,11,5,1,1800,216000,720,86400,900,54000,360,21600,166,2878,100,1788;QS=0.371728,0.628272;VDB=0.00189453;SGB=-0.616816;RPBZ=-2.81289;MQBZ=0;MQSBZ=0;BQBZ=-1.67266;SCBZ=-2.52262;MQ0F=0 PL:AD 129,0,28:15,6 000000F 656 . A <*> 0 . DP=11;I16=4,7,0,0,404,15690,0,0,660,39600,0,0,141,2411,0,0;QS=1,0;MQ0F=0 PL:AD 0,33,255:11,0 000000F 657 . C <*> 0 . DP=11;I16=4,7,0,0,413,15607,0,0,660,39600,0,0,131,2189,0,0;QS=1,0;MQ0F=0 PL:AD 0,33,255:11,0 000000F 658 . A <*> 0 . DP=10;I16=3,7,0,0,121,1651,0,0,600,36000,0,0,122,1986,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,79:10,0 000000F 658 . AA AAATTA 0 . INDEL;IDV=2;IMF=0.125;DP=16;I16=5,6,1,2,1100,110000,300,30000,660,39600,180,10800,141,2389,50,902;QS=0.418605,0.581395;VDB=0.045681;SGB=-0.511536;RPBZ=-1.70026;MQBZ=0;MQSBZ=0;BQBZ=-1.67266;SCBZ=-1.35678;MQ0F=0 PL:AD 76,0,29:11,3 000000F 659 . A <*> 0 . DP=10;I16=3,5,0,0,86,1088,0,0,480,28800,0,0,75,1077,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,63:8,0 000000F 660 . T <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL:AD 0,0,0:0,0 000000F 661 . A <*> 0 . DP=8;I16=0,2,0,0,8,32,0,0,120,7200,0,0,26,340,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,7:2,0 000000F 662 . C <*> 0 . DP=8;I16=0,2,0,0,10,50,0,0,120,7200,0,0,24,290,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,9:2,0 000000F 663 . A <*> 0 . DP=8;I16=5,3,0,0,40,224,0,0,480,28800,0,0,107,1627,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,24:8,0 000000F 664 . A <*> 0 . DP=8;I16=5,3,0,0,94,1646,0,0,480,28800,0,0,99,1421,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,69:8,0 000000F 665 . A <*> 0 . DP=8;I16=5,3,0,0,165,3551,0,0,480,28800,0,0,91,1231,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,124:8,0 000000F 666 . T <*> 0 . DP=8;I16=5,3,0,0,269,9361,0,0,480,28800,0,0,83,1057,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,207:8,0 000000F 667 . T <*> 0 . DP=8;I16=5,3,0,0,279,10001,0,0,480,28800,0,0,75,899,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,214:8,0 000000F 668 . A <*> 0 . DP=8;I16=5,3,0,0,278,10018,0,0,480,28800,0,0,67,757,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,214:8,0 000000F 669 . C <*> 0 . DP=8;I16=5,3,0,0,279,10051,0,0,480,28800,0,0,59,631,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,214:8,0 000000F 670 . A <*> 0 . DP=8;I16=5,3,0,0,287,10675,0,0,480,28800,0,0,51,521,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,220:8,0 000000F 671 . T <*> 0 . DP=8;I16=5,3,0,0,264,9116,0,0,480,28800,0,0,43,427,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,205:8,0 000000F 672 . C <*> 0 . DP=7;I16=4,3,0,0,237,8337,0,0,420,25200,0,0,36,348,0,0;QS=1,0;MQ0F=0 PL:AD 0,21,193:7,0 000000F 673 . T <*> 0 . DP=7;I16=4,3,0,0,223,7385,0,0,420,25200,0,0,29,283,0,0;QS=1,0;MQ0F=0 PL:AD 0,21,181:7,0 000000F 674 . A <*> 0 . DP=6;I16=4,2,0,0,199,6757,0,0,360,21600,0,0,23,231,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,164:6,0 000000F 675 . G <*> 0 . DP=4;I16=2,2,0,0,147,5443,0,0,240,14400,0,0,19,189,0,0;QS=1,0;MQ0F=0 PL:AD 0,12,134:4,0 000000F 676 . A <*> 0 . DP=3;I16=2,1,0,0,100,3434,0,0,180,10800,0,0,16,154,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,95:3,0 000000F 677 . T <*> 0 . DP=3;I16=2,1,0,0,104,3846,0,0,180,10800,0,0,13,125,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,100:3,0 000000F 678 . A <*> 0 . DP=2;I16=1,1,0,0,53,1825,0,0,120,7200,0,0,11,101,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,53:2,0 000000F 679 . T <*> 0 . DP=2;I16=1,1,0,0,68,2410,0,0,120,7200,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,68:2,0 000000F 680 . T <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,41:1,0 000000F 681 . T <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,41:1,0 000000F 682 . G <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,41:1,0 000000F 683 . T <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,35:1,0 000000F 684 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,31:1,0 000000F 685 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,29:1,0 000000F 686 . T <*> 0 . DP=1;I16=0,1,0,0,3,9,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,4:1,0 000000F 687 . N <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL:AD 0,0,0:0,0 000000F 688 . N <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL:AD 0,0,0:0,0 bcftools-1.21/test/mpileup/indel-AD.1.sam000066400000000000000000002107721467060157400201430ustar00rootroot00000000000000@HD VN:1.4 SO:coordinate @SQ SN:000000F LN:686 @RG ID:rg SM:sample ST-E00128:308:HHVVLALXX:8:1210:16660:4227 163 000000F 392 60 147M1D4M = 765 466 CATGTACTCGCATGAGAGTTATGTGTAAAACAGAGCTCAATTTTATTTTGTATTTATTGTGCAGTTAGAAAATAATATGATCAAATCTGTTTGTTTACCTGTGTTGTTTGTGTGCTCCCTCTGCGTGCTGGCTATCATGTCAGGTACGGTC AAAFFJJFJJAJJJJJJJJFJJJJJJFJJJJJFJFJJJJFJJJJJJJJJJJJJJJFJJJJJJJJJJJFFJJJJJJJJJJJJJJJFJJJFAJFJJAJJJ- ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 000000F 392 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,32:1,0 000000F 393 . A <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,32:1,0 000000F 394 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,32:1,0 000000F 395 . G <*> 0 . DP=3;I16=1,2,0,0,76,2242,0,0,180,10800,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,73:3,0 000000F 396 . T <*> 0 . DP=3;I16=1,2,0,0,86,2882,0,0,180,10800,0,0,6,18,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,83:3,0 000000F 397 . A <*> 0 . DP=3;I16=1,2,0,0,80,2554,0,0,180,10800,0,0,9,33,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,77:3,0 000000F 398 . C <*> 0 . DP=3;I16=1,2,0,0,75,2309,0,0,180,10800,0,0,12,54,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,72:3,0 000000F 399 . T <*> 0 . DP=3;I16=1,2,0,0,86,2582,0,0,180,10800,0,0,15,81,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,82:3,0 000000F 400 . C T,<*> 0 . DP=3;I16=1,1,0,1,63,2165,12,144,120,7200,60,3600,13,89,5,25;QS=0.84,0.16,0;SGB=-0.379885;RPBZ=-0.707107;MQBZ=0;MQSBZ=0;BQBZ=-1.22474;SCBZ=0;MQ0F=0 PL:AD 3,0,54,9,57,61:2,1,0 000000F 401 . G <*> 0 . DP=3;I16=1,2,0,0,65,1969,0,0,180,10800,0,0,21,153,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,62:3,0 000000F 402 . C <*> 0 . DP=5;I16=1,3,0,0,83,2041,0,0,240,14400,0,0,24,198,0,0;QS=1,0;MQ0F=0 PL:AD 0,12,75:4,0 000000F 403 . A <*> 0 . DP=5;I16=2,3,0,0,102,2818,0,0,300,18000,0,0,29,251,0,0;QS=1,0;MQ0F=0 PL:AD 0,15,91:5,0 000000F 404 . T <*> 0 . DP=5;I16=2,3,0,0,141,4875,0,0,300,18000,0,0,34,314,0,0;QS=1,0;MQ0F=0 PL:AD 0,15,127:5,0 000000F 405 . G <*> 0 . DP=6;I16=3,3,0,0,175,6043,0,0,360,21600,0,0,39,387,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,150:6,0 000000F 406 . A T,<*> 0 . DP=6;I16=3,2,0,1,143,5019,12,144,300,18000,60,3600,34,350,11,121;QS=0.922581,0.0774194,0;SGB=-0.379885;RPBZ=0.603023;MQBZ=0;MQSBZ=0;BQBZ=-0.948683;SCBZ=-0.447214;MQ0F=0 PL:AD 0,5,117,15,120,122:5,1,0 000000F 407 . G <*> 0 . DP=6;I16=3,3,0,0,170,5748,0,0,360,21600,0,0,51,567,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,148:6,0 000000F 408 . A <*> 0 . DP=6;I16=3,3,0,0,150,4818,0,0,360,21600,0,0,57,675,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,130:6,0 000000F 409 . G <*> 0 . DP=6;I16=3,3,0,0,194,6940,0,0,360,21600,0,0,63,795,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,166:6,0 000000F 410 . T <*> 0 . DP=7;I16=4,3,0,0,157,4587,0,0,420,25200,0,0,88,1288,0,0;QS=1,0;MQ0F=0 PL:AD 0,21,132:7,0 000000F 411 . T <*> 0 . DP=8;I16=5,3,0,0,255,8901,0,0,480,28800,0,0,115,1871,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,196:8,0 000000F 412 . A G,<*> 0 . DP=8;I16=5,2,0,1,235,8721,8,64,420,25200,60,3600,113,2009,10,100;QS=0.967078,0.0329218,0;SGB=-0.379885;RPBZ=0;MQBZ=0;MQSBZ=0;BQBZ=-1.62747;SCBZ=-0.75;MQ0F=0 PL:AD 0,14,175,21,178,176:7,1,0 000000F 413 . T <*> 0 . DP=9;I16=5,4,0,0,288,10546,0,0,540,32400,0,0,131,2363,0,0;QS=1,0;MQ0F=0 PL:AD 0,27,214:9,0 000000F 414 . G <*> 0 . DP=9;I16=5,4,0,0,317,12083,0,0,540,32400,0,0,140,2634,0,0;QS=1,0;MQ0F=0 PL:AD 0,27,236:9,0 000000F 415 . T G,<*> 0 . DP=9;I16=5,3,0,1,291,10937,22,484,480,28800,60,3600,136,2754,13,169;QS=0.929712,0.0702875,0;SGB=-0.379885;RPBZ=0.195283;MQBZ=0;MQSBZ=0;BQBZ=-1.5;SCBZ=-0.690269;MQ0F=0 PL:AD 0,5,202,24,205,214:8,1,0 000000F 416 . G C,<*> 0 . DP=10;I16=6,3,0,1,324,11944,12,144,540,32400,60,3600,144,3034,14,196;QS=0.964286,0.0357143,0;SGB=-0.379885;RPBZ=0.350285;MQBZ=0;MQSBZ=0;BQBZ=-1.62698;SCBZ=-0.642529;MQ0F=0 PL:AD 0,17,225,27,228,228:9,1,0 000000F 417 . T <*> 0 . DP=10;I16=6,4,0,0,364,13992,0,0,600,36000,0,0,166,3454,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,255:10,0 000000F 418 . A <*> 0 . DP=10;I16=6,4,0,0,360,13680,0,0,600,36000,0,0,173,3643,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,254:10,0 000000F 419 . A <*> 0 . DP=10;I16=6,4,0,0,344,13112,0,0,600,36000,0,0,180,3846,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,242:10,0 000000F 420 . A C,<*> 0 . DP=11;I16=7,3,0,1,306,11440,12,144,600,36000,60,3600,190,4180,18,324;QS=0.962382,0.0376176,0;SGB=-0.379885;RPBZ=0.476513;MQBZ=0;MQSBZ=0;BQBZ=-1.00766;SCBZ=-0.73252;MQ0F=0 PL:AD 0,20,212,30,215,215:10,1,0 000000F 421 . A <*> 0 . DP=12;I16=8,4,0,0,388,13950,0,0,720,43200,0,0,236,5160,0,0;QS=1,0;MQ0F=0 PL:AD 0,36,255:12,0 000000F 422 . C <*> 0 . DP=13;I16=8,5,0,0,484,18266,0,0,780,46800,0,0,243,5389,0,0;QS=1,0;MQ0F=0 PL:AD 0,39,255:13,0 000000F 423 . A <*> 0 . DP=15;I16=9,6,0,0,509,18579,0,0,900,54000,0,0,266,5858,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 424 . G <*> 0 . DP=15;I16=9,6,0,0,516,19368,0,0,900,54000,0,0,276,6150,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 425 . A <*> 0 . DP=15;I16=9,6,0,0,516,19668,0,0,900,54000,0,0,284,6360,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 426 . G T,<*> 0 . DP=15;I16=9,5,0,1,519,20109,12,144,840,50400,60,3600,288,6570,4,16;QS=0.977401,0.0225989,0;SGB=-0.379885;RPBZ=-1.28103;MQBZ=0;MQSBZ=0;BQBZ=-1.70698;SCBZ=-0.879593;MQ0F=0 PL:AD 0,31,255,42,255,255:14,1,0 000000F 427 . C <*> 0 . DP=15;I16=9,6,0,0,550,21100,0,0,900,54000,0,0,300,6828,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 428 . T <*> 0 . DP=15;I16=9,6,0,0,521,19363,0,0,900,54000,0,0,306,6984,0,0;QS=1,0;MQ0F=0 PL:AD 0,45,255:15,0 000000F 429 . C A,<*> 0 . DP=17;I16=10,6,0,1,533,19507,12,144,960,57600,60,3600,287,6527,25,625;QS=0.977982,0.0220183,0;SGB=-0.379885;RPBZ=1.33584;MQBZ=0;MQSBZ=0;BQBZ=-1.55274;SCBZ=-0.887279;MQ0F=0 PL:AD 0,37,255,48,255,255:16,1,0 000000F 430 . A <*> 0 . DP=18;I16=10,8,0,0,583,20803,0,0,1080,64800,0,0,320,7334,0,0;QS=1,0;MQ0F=0 PL:AD 0,54,255:18,0 000000F 431 . A <*> 0 . DP=19;I16=10,8,0,0,616,23012,0,0,1080,64800,0,0,328,7482,0,0;QS=1,0;MQ0F=0 PL:AD 0,54,255:18,0 000000F 432 . T <*> 0 . DP=19;I16=11,8,0,0,682,26264,0,0,1140,68400,0,0,337,7647,0,0;QS=1,0;MQ0F=0 PL:AD 0,57,255:19,0 000000F 433 . T <*> 0 . DP=19;I16=11,8,0,0,696,26452,0,0,1140,68400,0,0,346,7830,0,0;QS=1,0;MQ0F=0 PL:AD 0,57,255:19,0 000000F 434 . T <*> 0 . DP=19;I16=11,8,0,0,678,25728,0,0,1140,68400,0,0,354,7980,0,0;QS=1,0;MQ0F=0 PL:AD 0,57,255:19,0 000000F 435 . T <*> 0 . DP=20;I16=11,9,0,0,717,26931,0,0,1200,72000,0,0,362,8146,0,0;QS=1,0;MQ0F=0 PL:AD 0,60,255:20,0 000000F 436 . A C,<*> 0 . DP=21;I16=11,9,0,1,728,28034,12,144,1200,72000,60,3600,346,7704,25,625;QS=0.983784,0.0162162,0;SGB=-0.379885;RPBZ=0.909477;MQBZ=0;MQSBZ=0;BQBZ=-1.66309;SCBZ=-0.82685;MQ0F=0 PL:AD 0,49,255,60,255,255:20,1,0 000000F 437 . T <*> 0 . DP=21;I16=11,10,0,0,770,29698,0,0,1260,75600,0,0,381,8531,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 438 . T <*> 0 . DP=22;I16=11,10,0,0,726,26976,0,0,1260,75600,0,0,391,8753,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 439 . T <*> 0 . DP=25;I16=14,10,0,0,804,30038,0,0,1440,86400,0,0,444,9912,0,0;QS=1,0;MQ0F=0 PL:AD 0,72,255:24,0 000000F 440 . T A,<*> 0 . DP=27;I16=15,11,1,0,896,33856,12,144,1560,93600,60,3600,455,10163,25,625;QS=0.986784,0.0132159,0;SGB=-0.379885;RPBZ=1.28585;MQBZ=0;MQSBZ=0;BQBZ=-1.41134;SCBZ=0.48519;MQ0F=0 PL:AD 0,66,255,78,255,255:26,1,0 000000F 441 . G <*> 0 . DP=29;I16=17,11,0,0,1033,39137,0,0,1680,100800,0,0,495,11163,0,0;QS=1,0;MQ0F=0 PL:AD 0,84,255:28,0 000000F 442 . T <*> 0 . DP=29;I16=18,11,0,0,1067,41223,0,0,1740,104400,0,0,531,11951,0,0;QS=1,0;MQ0F=0 PL:AD 0,87,255:29,0 000000F 443 . A <*> 0 . DP=31;I16=20,11,0,0,1078,40562,0,0,1860,111600,0,0,544,12226,0,0;QS=1,0;MQ0F=0 PL:AD 0,93,255:31,0 000000F 444 . T <*> 0 . DP=31;I16=20,11,0,0,1124,43000,0,0,1860,111600,0,0,559,12529,0,0;QS=1,0;MQ0F=0 PL:AD 0,93,255:31,0 000000F 445 . T <*> 0 . DP=32;I16=20,11,0,0,1050,38808,0,0,1860,111600,0,0,574,12862,0,0;QS=1,0;MQ0F=0 PL:AD 0,93,255:31,0 000000F 446 . T <*> 0 . DP=34;I16=22,11,0,0,1205,45921,0,0,1980,118800,0,0,611,13703,0,0;QS=1,0;MQ0F=0 PL:AD 0,99,255:33,0 000000F 447 . A <*> 0 . DP=35;I16=23,12,0,0,1177,43259,0,0,2100,126000,0,0,650,14620,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 448 . T <*> 0 . DP=35;I16=23,12,0,0,1220,45736,0,0,2100,126000,0,0,667,15037,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 449 . T <*> 0 . DP=35;I16=23,12,0,0,1249,47703,0,0,2100,126000,0,0,679,15245,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 450 . G <*> 0 . DP=38;I16=25,13,0,0,1449,56453,0,0,2280,136800,0,0,715,16059,0,0;QS=1,0;MQ0F=0 PL:AD 0,114,255:38,0 000000F 451 . T A,<*> 0 . DP=43;I16=24,16,0,1,1485,57079,12,144,2400,144000,60,3600,708,15882,0,0;QS=0.991984,0.00801603,0;SGB=-0.379885;RPBZ=-1.56545;MQBZ=0;MQSBZ=0;BQBZ=-1.91213;SCBZ=-0.839032;MQ0F=0 PL:AD 0,107,255,120,255,255:40,1,0 000000F 452 . G T,<*> 0 . DP=45;I16=24,18,0,1,1541,58723,12,144,2520,151200,60,3600,707,15841,23,529;QS=0.992273,0.00772698,0;SGB=-0.379885;RPBZ=0.645561;MQBZ=0;MQSBZ=0;BQBZ=-1.75577;SCBZ=0.629801;MQ0F=0 PL:AD 0,113,255,126,255,255:42,1,0 000000F 453 . C <*> 0 . DP=45;I16=24,19,0,0,1623,65335,0,0,2580,154800,0,0,753,16853,0,0;QS=1,0;MQ0F=0 PL:AD 0,129,255:43,0 000000F 454 . A C,<*> 0 . DP=47;I16=24,20,1,0,1699,68295,12,144,2640,158400,60,3600,774,17286,25,625;QS=0.992987,0.00701344,0;SGB=-0.379885;RPBZ=1.46482;MQBZ=0;MQSBZ=0;BQBZ=-1.87433;SCBZ=0.550575;MQ0F=0 PL:AD 0,119,255,132,255,255:44,1,0 000000F 455 . G <*> 0 . DP=48;I16=26,20,0,0,1807,74553,0,0,2760,165600,0,0,823,18385,0,0;QS=1,0;MQ0F=0 PL:AD 0,138,255:46,0 000000F 456 . T <*> 0 . DP=49;I16=26,21,0,0,1757,69583,0,0,2820,169200,0,0,845,18853,0,0;QS=1,0;MQ0F=0 PL:AD 0,141,255:47,0 000000F 457 . T <*> 0 . DP=49;I16=26,21,0,0,1836,73528,0,0,2820,169200,0,0,866,19264,0,0;QS=1,0;MQ0F=0 PL:AD 0,141,255:47,0 000000F 458 . A <*> 0 . DP=50;I16=26,22,0,0,1817,72337,0,0,2880,172800,0,0,887,19717,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 459 . G <*> 0 . DP=50;I16=26,22,0,0,1791,70171,0,0,2880,172800,0,0,909,20213,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 460 . A <*> 0 . DP=49;I16=26,22,0,0,1675,63873,0,0,2880,172800,0,0,923,20689,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 461 . A T,C,<*> 0 . DP=52;I16=25,22,1,1,1650,63298,24,288,2820,169200,120,7200,927,21061,17,145;QS=0.985663,0.00716846,0.00716846,0;VDB=0.06;SGB=-0.453602;RPBZ=-1.92231;MQBZ=0;MQSBZ=0;BQBZ=-2.2578;SCBZ=-0.055422;MQ0F=0 PL:AD 0,128,255,128,255,255,141,255,255,255:47,1,1,0 000000F 462 . A T,<*> 0 . DP=52;I16=26,22,0,1,1705,65163,12,144,2880,172800,60,3600,955,21615,10,100;QS=0.993011,0.00698893,0;SGB=-0.379885;RPBZ=-1.09702;MQBZ=0;MQSBZ=0;BQBZ=-1.74927;SCBZ=-0.853241;MQ0F=0 PL:AD 0,130,255,144,255,255:48,1,0 000000F 463 . A <*> 0 . DP=52;I16=26,24,0,0,1836,71956,0,0,3000,180000,0,0,996,22366,0,0;QS=1,0;MQ0F=0 PL:AD 0,151,255:50,0 000000F 464 . T G,<*> 0 . DP=52;I16=26,23,0,1,1873,73813,12,144,2940,176400,60,3600,993,22355,25,625;QS=0.993634,0.00636605,0;SGB=-0.379885;RPBZ=0.173386;MQBZ=0;MQSBZ=0;BQBZ=-1.93908;SCBZ=-0.840331;MQ0F=0 PL:AD 0,133,255,148,255,255:49,1,0 000000F 465 . A <*> 0 . DP=52;I16=26,24,0,0,1950,78232,0,0,3000,180000,0,0,1039,23587,0,0;QS=1,0;MQ0F=0 PL:AD 0,151,255:50,0 000000F 466 . A C,<*> 0 . DP=52;I16=25,24,1,0,1858,74740,12,144,2940,176400,60,3600,1033,23509,25,625;QS=0.993583,0.00641711,0;SGB=-0.379885;RPBZ=-1.24865;MQBZ=0;MQSBZ=0;BQBZ=-1.79438;SCBZ=1.87165;MQ0F=0 PL:AD 0,133,255,148,255,255:49,1,0 000000F 467 . T <*> 0 . DP=53;I16=26,25,0,0,1890,74962,0,0,3060,183600,0,0,1076,24668,0,0;QS=1,0;MQ0F=0 PL:AD 0,154,255:51,0 000000F 468 . A <*> 0 . DP=54;I16=27,25,0,0,1967,78281,0,0,3120,187200,0,0,1095,25239,0,0;QS=1,0;MQ0F=0 PL:AD 0,157,255:52,0 000000F 469 . T <*> 0 . DP=54;I16=27,25,0,0,2046,83348,0,0,3120,187200,0,0,1113,25747,0,0;QS=1,0;MQ0F=0 PL:AD 0,157,255:52,0 000000F 470 . G <*> 0 . DP=55;I16=28,25,0,0,2047,81939,0,0,3180,190800,0,0,1131,26291,0,0;QS=1,0;MQ0F=0 PL:AD 0,160,255:53,0 000000F 471 . A <*> 0 . DP=56;I16=28,26,0,0,2028,80100,0,0,3240,194400,0,0,1150,26872,0,0;QS=1,0;MQ0F=0 PL:AD 0,163,255:54,0 000000F 472 . T <*> 0 . DP=59;I16=29,28,0,0,2122,83726,0,0,3420,205200,0,0,1191,27925,0,0;QS=1,0;MQ0F=0 PL:AD 0,172,255:57,0 000000F 473 . C A,G,<*> 0 . DP=63;I16=19,15,12,13,1263,49285,963,39221,2040,122400,1500,90000,705,16449,548,12960;QS=0.567385,0.427224,0.00539084,0;VDB=1.64281e-06;SGB=-0.692914;RPBZ=1.05908;MQBZ=0;MQSBZ=0;BQBZ=1.40915;SCBZ=0.597801;MQ0F=0 PL:AD 255,0,255,255,255,255,255,255,255,255:34,24,1,0 000000F 474 . A <*> 0 . DP=64;I16=33,28,0,0,2172,84276,0,0,3660,219600,0,0,1296,30488,0,0;QS=1,0;MQ0F=0 PL:AD 0,184,255:61,0 000000F 475 . A <*> 0 . DP=64;I16=34,28,0,0,2092,79478,0,0,3720,223200,0,0,1322,31258,0,0;QS=1,0;MQ0F=0 PL:AD 0,187,255:62,0 000000F 476 . A G,<*> 0 . DP=65;I16=34,28,0,1,2176,83678,12,144,3720,223200,60,3600,1319,31299,25,625;QS=0.994516,0.00548446,0;SGB=-0.379885;RPBZ=1.04564;MQBZ=0;MQSBZ=0;BQBZ=-1.59705;SCBZ=0.713967;MQ0F=0 PL:AD 0,172,255,187,255,255:62,1,0 000000F 477 . T G,<*> 0 . DP=65;I16=34,28,0,1,2352,93436,12,144,3720,223200,60,3600,1338,31806,25,625;QS=0.994924,0.00507614,0;SGB=-0.379885;RPBZ=-0.687896;MQBZ=0;MQSBZ=0;BQBZ=-1.84472;SCBZ=-0.892396;MQ0F=0 PL:AD 0,172,255,187,255,255:62,1,0 000000F 478 . C <*> 0 . DP=65;I16=34,29,0,0,2376,94566,0,0,3780,226800,0,0,1381,32925,0,0;QS=1,0;MQ0F=0 PL:AD 0,190,255:63,0 000000F 479 . T G,<*> 0 . DP=68;I16=36,29,0,1,2467,98357,12,144,3900,234000,60,3600,1416,33712,21,441;QS=0.995159,0.00484066,0;SGB=-0.379885;RPBZ=-0.787962;MQBZ=0;MQSBZ=0;BQBZ=-1.86106;SCBZ=-0.927153;MQ0F=0 PL:AD 0,180,255,196,255,255:65,1,0 000000F 480 . G <*> 0 . DP=70;I16=38,30,0,0,2563,101527,0,0,4080,244800,0,0,1495,35435,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 481 . T <*> 0 . DP=70;I16=38,30,0,0,2521,98551,0,0,4080,244800,0,0,1514,35994,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 482 . T G,<*> 0 . DP=70;I16=37,30,1,0,2575,103005,12,144,4020,241200,60,3600,1518,36344,14,196;QS=0.995361,0.00463858,0;SGB=-0.379885;RPBZ=-0.892198;MQBZ=0;MQSBZ=0;BQBZ=-1.93937;SCBZ=-0.948507;MQ0F=0 PL:AD 0,186,255,202,255,255:67,1,0 000000F 483 . T <*> 0 . DP=70;I16=38,30,0,0,2646,106206,0,0,4080,244800,0,0,1549,37071,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 484 . G <*> 0 . DP=70;I16=38,30,0,0,2659,107225,0,0,4080,244800,0,0,1565,37585,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 485 . T <*> 0 . DP=70;I16=38,30,0,0,2618,104932,0,0,4080,244800,0,0,1578,37978,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 486 . T <*> 0 . DP=70;I16=38,30,0,0,2589,103545,0,0,4080,244800,0,0,1589,38295,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 000000F 487 . T <*> 0 . DP=73;I16=38,33,0,0,2694,107284,0,0,4260,255600,0,0,1599,38583,0,0;QS=1,0;MQ0F=0 PL:AD 0,214,255:71,0 000000F 488 . A G,<*> 0 . DP=76;I16=41,32,0,1,2640,102296,8,64,4380,262800,60,3600,1679,40447,1,1;QS=0.996979,0.00302115,0;SGB=-0.379885;RPBZ=-1.52228;MQBZ=0;MQSBZ=0;BQBZ=-1.89405;SCBZ=-0.946449;MQ0F=0 PL:AD 0,204,255,220,255,255:73,1,0 000000F 489 . C A,<*> 0 . DP=79;I16=43,33,0,1,2694,103126,12,144,4560,273600,60,3600,1715,41273,25,625;QS=0.995565,0.00443459,0;SGB=-0.379885;RPBZ=-0.495167;MQBZ=0;MQSBZ=0;BQBZ=-1.58784;SCBZ=-0.974263;MQ0F=0 PL:AD 0,213,255,229,255,255:76,1,0 000000F 490 . C <*> 0 . DP=80;I16=43,35,0,0,2796,107040,0,0,4680,280800,0,0,1782,43020,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 491 . T <*> 0 . DP=80;I16=43,35,0,0,2910,113818,0,0,4680,280800,0,0,1798,43500,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 492 . G <*> 0 . DP=81;I16=43,35,0,0,3089,125687,0,0,4680,280800,0,0,1814,44012,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 493 . T <*> 0 . DP=81;I16=43,35,0,0,2986,119178,0,0,4680,280800,0,0,1829,44505,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 494 . G <*> 0 . DP=81;I16=43,35,0,0,3060,125030,0,0,4680,280800,0,0,1842,44926,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 495 . T <*> 0 . DP=84;I16=45,36,0,0,3053,121389,0,0,4860,291600,0,0,1898,46292,0,0;QS=1,0;MQ0F=0 PL:AD 0,244,255:81,0 000000F 496 . T <*> 0 . DP=87;I16=47,37,0,0,3238,128760,0,0,5040,302400,0,0,1917,46777,0,0;QS=1,0;MQ0F=0 PL:AD 0,253,255:84,0 000000F 497 . G <*> 0 . DP=87;I16=47,37,0,0,3280,132640,0,0,5040,302400,0,0,1933,47227,0,0;QS=1,0;MQ0F=0 PL:AD 0,253,255:84,0 000000F 498 . T <*> 0 . DP=88;I16=48,37,0,0,3081,120187,0,0,5100,306000,0,0,1971,48181,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 499 . T C,<*> 0 . DP=89;I16=48,36,0,1,3190,126958,8,64,5040,302400,60,3600,1957,47809,25,625;QS=0.997498,0.00250156,0;SGB=-0.379885;RPBZ=-0.305833;MQBZ=0;MQSBZ=0;BQBZ=-1.95559;SCBZ=-1.05778;MQ0F=0 PL:AD 0,237,255,253,255,255:84,1,0 000000F 500 . T G,A,<*> 0 . DP=92;I16=50,37,1,1,3308,133104,24,288,5220,313200,120,7200,1986,48376,50,1250;QS=0.992797,0.00360144,0.00360144,0;VDB=0.32;SGB=-0.453602;RPBZ=0.41539;MQBZ=0;MQSBZ=0;BQBZ=-2.60206;SCBZ=-1.0009;MQ0F=0 PL:AD 0,245,255,245,255,255,255,255,255,255:87,1,1,0 000000F 501 . G <*> 0 . DP=97;I16=53,40,0,0,3485,138049,0,0,5580,334800,0,0,2050,49962,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:93,0 000000F 502 . T A,<*> 0 . DP=98;I16=53,40,1,0,3391,132771,12,144,5580,334800,60,3600,2065,50183,25,625;QS=0.996476,0.00352423,0;SGB=-0.379885;RPBZ=1.67751;MQBZ=0;MQSBZ=0;BQBZ=-1.7355;SCBZ=0.856937;MQ0F=0 PL:AD 0,255,255,255,255,255:93,1,0 000000F 503 . G <*> 0 . DP=98;I16=54,40,0,0,3540,140610,0,0,5640,338400,0,0,2108,51206,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:94,0 000000F 504 . T C,A,<*> 0 . DP=102;I16=53,42,1,1,3464,137680,20,208,5700,342000,120,7200,2099,50913,25,625;QS=0.994259,0.00344432,0.00229621,0;VDB=0.92;SGB=-0.453602;RPBZ=0.0126977;MQBZ=0;MQSBZ=0;BQBZ=-2.43319;SCBZ=0.512446;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:95,1,1,0 000000F 505 . G <*> 0 . DP=102;I16=54,43,0,0,3640,144678,0,0,5820,349200,0,0,2141,51803,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 506 . C G,<*> 0 . DP=103;I16=54,43,0,1,3621,145273,12,144,5820,349200,60,3600,2138,51502,25,625;QS=0.996697,0.00330306,0;SGB=-0.379885;RPBZ=0.194473;MQBZ=0;MQSBZ=0;BQBZ=-1.75415;SCBZ=-1.07827;MQ0F=0 PL:AD 0,255,255,255,255,255:97,1,0 000000F 507 . T <*> 0 . DP=103;I16=54,44,0,0,3520,139202,0,0,5880,352800,0,0,2181,52471,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:98,0 000000F 508 . C T,<*> 0 . DP=103;I16=54,43,0,1,3476,137498,12,144,5820,349200,60,3600,2174,52226,25,625;QS=0.99656,0.00344037,0;SGB=-0.379885;RPBZ=0.265217;MQBZ=0;MQSBZ=0;BQBZ=-1.63996;SCBZ=-1.07818;MQ0F=0 PL:AD 0,255,255,255,255,255:97,1,0 000000F 509 . C <*> 0 . DP=103;I16=54,44,0,0,3580,142206,0,0,5880,352800,0,0,2217,53267,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:98,0 000000F 510 . C A,G,<*> 0 . DP=106;I16=54,43,1,2,3646,145190,42,692,5820,349200,180,10800,2189,52645,67,1515;QS=0.988612,0.00921909,0.0021692,0;VDB=0.401962;SGB=-0.511536;RPBZ=-0.707412;MQBZ=0;MQSBZ=0;BQBZ=-3.02794;SCBZ=-0.99293;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:97,2,1,0 000000F 511 . T A,<*> 0 . DP=107;I16=55,45,0,1,3663,144413,12,144,6000,360000,60,3600,2251,54067,25,625;QS=0.996735,0.00326531,0;SGB=-0.379885;RPBZ=-0.0343102;MQBZ=0;MQSBZ=0;BQBZ=-1.71065;SCBZ=-1.08137;MQ0F=0 PL:AD 0,255,255,255,255,255:100,1,0 000000F 512 . C A,G,<*> 0 . DP=107;I16=55,43,1,3,3657,146609,54,836,5880,352800,240,14400,2238,53902,83,1939;QS=0.985449,0.0123956,0.00215575,0;VDB=0.681156;SGB=-0.556411;RPBZ=-0.465574;MQBZ=0;MQSBZ=0;BQBZ=-3.45917;SCBZ=-0.667699;MQ0F=0 PL:AD 0,248,255,255,255,255,255,255,255,255:98,3,1,0 000000F 513 . T G,<*> 0 . DP=108;I16=56,46,0,1,3774,150038,7,49,6120,367200,60,3600,2340,56352,0,0;QS=0.998149,0.00185136,0;SGB=-0.379885;RPBZ=-1.71577;MQBZ=0;MQSBZ=0;BQBZ=-1.90666;SCBZ=-1.07835;MQ0F=0 PL:AD 0,255,255,255,255,255:102,1,0 000000F 514 . G T,<*> 0 . DP=110;I16=56,47,1,1,3763,148539,20,208,6180,370800,120,7200,2348,56422,25,625;QS=0.994713,0.00528681,0;VDB=0.44;SGB=-0.453602;RPBZ=-1.58286;MQBZ=0;MQSBZ=0;BQBZ=-2.48498;SCBZ=0.0121282;MQ0F=0 PL:AD 0,255,255,255,255,255:103,2,0 000000F 515 . C G,<*> 0 . DP=110;I16=57,47,0,1,3848,153002,12,144,6240,374400,60,3600,2367,56887,25,625;QS=0.996891,0.00310881,0;SGB=-0.379885;RPBZ=0.263997;MQBZ=0;MQSBZ=0;BQBZ=-1.75323;SCBZ=-1.07538;MQ0F=0 PL:AD 0,255,255,255,255,255:104,1,0 000000F 516 . G T,<*> 0 . DP=111;I16=57,48,0,1,3969,158573,12,144,6300,378000,60,3600,2411,58015,0,0;QS=0.996986,0.00301432,0;SGB=-0.379885;RPBZ=-1.71626;MQBZ=0;MQSBZ=0;BQBZ=-1.8341;SCBZ=-1.06697;MQ0F=0 PL:AD 0,255,255,255,255,255:105,1,0 000000F 517 . T C,<*> 0 . DP=112;I16=56,50,1,0,3850,151946,12,144,6360,381600,60,3600,2408,58016,21,441;QS=0.996893,0.0031072,0;SGB=-0.379885;RPBZ=-0.7772;MQBZ=0;MQSBZ=0;BQBZ=-1.67048;SCBZ=0.856997;MQ0F=0 PL:AD 0,255,255,255,255,255:106,1,0 000000F 518 . G <*> 0 . DP=115;I16=59,50,0,0,3977,155237,0,0,6540,392400,0,0,2447,58891,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 519 . C A,<*> 0 . DP=116;I16=60,49,0,1,4018,159736,12,144,6540,392400,60,3600,2443,58747,25,625;QS=0.997022,0.00297767,0;SGB=-0.379885;RPBZ=0.110257;MQBZ=0;MQSBZ=0;BQBZ=-1.72465;SCBZ=-1.03419;MQ0F=0 PL:AD 0,255,255,255,255,255:109,1,0 000000F 520 . T G,C,A 0 . DP=116;I16=59,48,1,2,4046,162680,48,1152,6420,385200,180,10800,2436,58644,53,1259;QS=0.988276,0.00781632,0.00195408,0.00195408;VDB=0.913952;SGB=-0.511536;RPBZ=0.578224;MQBZ=0;MQSBZ=0;BQBZ=-2.88822;SCBZ=-0.373153;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:107,1,1,1 000000F 521 . G A,T,<*> 0 . DP=118;I16=61,48,1,2,4131,166701,36,432,6540,392400,180,10800,2454,59246,53,1089;QS=0.991361,0.00575954,0.00287977,0;VDB=0.251321;SGB=-0.511536;RPBZ=-1.60419;MQBZ=0;MQSBZ=0;BQBZ=-3.05428;SCBZ=-0.836529;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:109,2,1,0 000000F 522 . G <*> 0 . DP=118;I16=62,50,0,0,4076,161128,0,0,6720,403200,0,0,2525,60719,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:112,0 000000F 523 . C A,<*> 0 . DP=119;I16=63,49,0,1,4174,166860,12,144,6720,403200,60,3600,2518,60530,25,625;QS=0.997133,0.0028667,0;SGB=-0.379885;RPBZ=-0.13799;MQBZ=0;MQSBZ=0;BQBZ=-1.80506;SCBZ=-1.02482;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 524 . T G,<*> 0 . DP=119;I16=62,50,1,0,4191,166163,27,729,6720,403200,60,3600,2537,61019,25,625;QS=0.993599,0.00640114,0;SGB=-0.379885;RPBZ=-0.82791;MQBZ=0;MQSBZ=0;BQBZ=-1.39926;SCBZ=0.0480382;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 525 . A C,G,<*> 0 . DP=119;I16=62,48,1,2,4098,163296,36,432,6600,396000,180,10800,2509,60447,71,1691;QS=0.991292,0.00580552,0.00290276,0;VDB=0.199299;SGB=-0.511536;RPBZ=-1.60781;MQBZ=0;MQSBZ=0;BQBZ=-2.97339;SCBZ=1.45142;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:110,2,1,0 000000F 526 . T A,<*> 0 . DP=120;I16=63,49,0,1,4180,166064,12,144,6720,403200,60,3600,2570,61910,25,625;QS=0.997137,0.0028626,0;SGB=-0.379885;RPBZ=-1.2266;MQBZ=0;MQSBZ=0;BQBZ=-1.74833;SCBZ=0.367327;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 527 . C G,A,<*> 0 . DP=120;I16=62,49,1,1,4246,172572,24,288,6660,399600,120,7200,2557,61573,48,1154;QS=0.994379,0.0028103,0.0028103,0;VDB=0.18;SGB=-0.453602;RPBZ=-1.28504;MQBZ=0;MQSBZ=0;BQBZ=-2.51884;SCBZ=1.10043;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:111,1,1,0 000000F 528 . A G,<*> 0 . DP=121;I16=62,51,1,0,4295,173733,12,144,6780,406800,60,3600,2588,62236,25,625;QS=0.997214,0.00278616,0;SGB=-0.379885;RPBZ=-0.805477;MQBZ=0;MQSBZ=0;BQBZ=-1.82642;SCBZ=0.0634184;MQ0F=0 PL:AD 0,255,255,255,255,255:113,1,0 000000F 529 . T C,<*> 0 . DP=123;I16=65,50,0,1,4363,176845,8,64,6900,414000,60,3600,2639,63305,25,625;QS=0.99817,0.00183024,0;SGB=-0.379885;RPBZ=-1.04546;MQBZ=0;MQSBZ=0;BQBZ=-1.9592;SCBZ=-1.04156;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 530 . G <*> 0 . DP=123;I16=65,51,0,0,4357,176035,0,0,6960,417600,0,0,2672,64088,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:116,0 000000F 531 . T A,G,<*> 0 . DP=123;I16=63,49,2,2,4199,169729,48,576,6720,403200,240,14400,2579,61741,100,2500;QS=0.988698,0.00847657,0.00282552,0;VDB=0.0550934;SGB=-0.556411;RPBZ=-0.650816;MQBZ=0;MQSBZ=0;BQBZ=-3.46139;SCBZ=-0.463641;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:112,3,1,0 000000F 532 . C A,G,<*> 0 . DP=124;I16=65,49,0,3,4352,176182,36,432,6840,410400,180,10800,2640,63492,45,897;QS=0.991796,0.00546946,0.00273473,0;VDB=0.588406;SGB=-0.511536;RPBZ=-1.58686;MQBZ=0;MQSBZ=0;BQBZ=-3.10955;SCBZ=-1.82952;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:114,2,1,0 000000F 533 . A <*> 0 . DP=124;I16=65,52,0,0,4235,168199,0,0,7020,421200,0,0,2692,64582,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:117,0 000000F 534 . G A,<*> 0 . DP=124;I16=65,51,0,1,4319,173543,12,144,6960,417600,60,3600,2677,64331,21,441;QS=0.997229,0.00277072,0;SGB=-0.379885;RPBZ=-1.3327;MQBZ=0;MQSBZ=0;BQBZ=-1.72023;SCBZ=-1.04702;MQ0F=0 PL:AD 0,255,255,255,255,255:116,1,0 000000F 535 . G A,<*> 0 . DP=125;I16=65,52,0,1,4309,171791,12,144,7020,421200,60,3600,2679,64385,25,625;QS=0.997223,0.00277713,0;SGB=-0.379885;RPBZ=-1.10121;MQBZ=0;MQSBZ=0;BQBZ=-1.74874;SCBZ=0.0762649;MQ0F=0 PL:AD 0,255,255,255,255,255:117,1,0 000000F 536 . T G,A,<*> 0 . DP=125;I16=65,51,0,2,4274,171298,24,288,6960,417600,120,7200,2661,64041,48,1154;QS=0.994416,0.002792,0.002792,0;VDB=0.1;SGB=-0.453602;RPBZ=-1.74128;MQBZ=0;MQSBZ=0;BQBZ=-2.39373;SCBZ=-0.693187;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:116,1,1,0 000000F 537 . A <*> 0 . DP=125;I16=65,53,0,0,4390,175290,0,0,7080,424800,0,0,2713,65375,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:118,0 000000F 537 . AC A 0 . INDEL;IDV=58;IMF=0.464;DP=125;I16=38,28,31,27,2640,105600,2320,92800,3960,237600,3480,208800,1498,35936,1313,31375;QS=0.532258,0.467742;VDB=0.457405;SGB=-0.693147;RPBZ=-0.543708;MQBZ=0;MQSBZ=0;BQBZ=-2.39373;SCBZ=0.641853;MQ0F=0 PL:AD 133,0,139:66,58 000000F 538 . C <*> 0 . DP=65;I16=36,26,0,0,2195,86349,0,0,3720,223200,0,0,1432,34600,0,0;QS=1,0;MQ0F=0 PL:AD 0,187,255:62,0 000000F 538 . CT C 0 . INDEL;IDV=65;IMF=0.52;DP=125;I16=31,27,37,28,2320,92800,2600,104000,3480,208800,3900,234000,1318,31556,1480,35714;QS=0.473469,0.526531;VDB=0.00206877;SGB=-0.693147;RPBZ=0.242079;MQBZ=0;MQSBZ=0;BQBZ=-2.39373;SCBZ=-0.994262;MQ0F=0 PL:AD 138,0,133:58,65 000000F 539 . T <*> 0 . DP=60;I16=29,26,0,0,2120,86238,0,0,3300,198000,0,0,1260,30374,0,0;QS=1,0;MQ0F=0 PL:AD 0,166,255:55,0 000000F 540 . G <*> 0 . DP=124;I16=64,53,0,0,4130,161310,0,0,7020,421200,0,0,2703,65511,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:117,0 000000F 541 . G <*> 0 . DP=124;I16=64,53,0,0,4143,160525,0,0,7020,421200,0,0,2705,65703,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:117,0 000000F 542 . T G,A,<*> 0 . DP=124;I16=63,52,1,1,4035,156631,24,288,6900,414000,120,7200,2657,64685,50,1250;QS=0.994087,0.00295639,0.00295639,0;VDB=0.26;SGB=-0.453602;RPBZ=-1.44078;MQBZ=0;MQSBZ=0;BQBZ=-2.25702;SCBZ=-0.906022;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:115,1,1,0 000000F 543 . C G,A,<*> 0 . DP=122;I16=62,53,1,1,4006,154170,24,288,6900,414000,120,7200,2673,65063,50,1250;QS=0.994045,0.00297767,0.00297767,0;VDB=0.22;SGB=-0.453602;RPBZ=-0.483734;MQBZ=0;MQSBZ=0;BQBZ=-2.21926;SCBZ=0.31726;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:115,1,1,0 000000F 544 . T A,<*> 0 . DP=121;I16=62,53,0,1,4151,162625,12,144,6900,414000,60,3600,2697,65733,25,625;QS=0.997117,0.00288254,0;SGB=-0.379885;RPBZ=0.238977;MQBZ=0;MQSBZ=0;BQBZ=-1.67238;SCBZ=-1.05505;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 545 . G A,<*> 0 . DP=121;I16=62,53,0,1,4078,158586,12,144,6900,414000,60,3600,2710,66228,8,64;QS=0.997066,0.00293399,0;SGB=-0.379885;RPBZ=1.6131;MQBZ=0;MQSBZ=0;BQBZ=-1.61213;SCBZ=-1.05503;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 546 . G A,<*> 0 . DP=121;I16=62,53,0,1,4230,164790,12,144,6900,414000,60,3600,2689,65637,25,625;QS=0.997171,0.00282885,0;SGB=-0.379885;RPBZ=-0.97077;MQBZ=0;MQSBZ=0;BQBZ=-1.77555;SCBZ=-1.0549;MQ0F=0 PL:AD 0,255,255,255,255,255:115,1,0 000000F 547 . A C,<*> 0 . DP=119;I16=62,51,0,1,4105,158737,12,144,6780,406800,60,3600,2686,65592,25,625;QS=0.997085,0.00291474,0;SGB=-0.379885;RPBZ=-0.896646;MQBZ=0;MQSBZ=0;BQBZ=-1.70779;SCBZ=0.0314879;MQ0F=0 PL:AD 0,255,255,255,255,255:113,1,0 000000F 548 . C G,<*> 0 . DP=119;I16=62,51,0,1,4014,154686,12,144,6780,406800,60,3600,2681,65479,25,625;QS=0.997019,0.00298063,0;SGB=-0.379885;RPBZ=-0.896728;MQBZ=0;MQSBZ=0;BQBZ=-1.67128;SCBZ=0.0314876;MQ0F=0 PL:AD 0,255,255,255,255,255:113,1,0 000000F 549 . C A,<*> 0 . DP=117;I16=33,29,29,22,2214,83510,1893,75363,3720,223200,3060,183600,1463,35977,1212,29370;QS=0.53908,0.46092,0;VDB=0.0978768;SGB=-0.693147;RPBZ=-0.600202;MQBZ=0;MQSBZ=0;BQBZ=1.17837;SCBZ=0.928426;MQ0F=0 PL:AD 255,0,255,255,255,255:62,51,0 000000F 550 . G T,<*> 0 . DP=117;I16=62,50,0,1,4113,161301,22,484,6720,403200,60,3600,2641,64473,25,625;QS=0.99468,0.00532044,0;SGB=-0.379885;RPBZ=-0.950536;MQBZ=0;MQSBZ=0;BQBZ=-1.55326;SCBZ=-1.07862;MQ0F=0 PL:AD 0,255,255,255,255,255:112,1,0 000000F 551 . G T,A,<*> 0 . DP=116;I16=60,50,1,1,4131,164089,24,288,6600,396000,120,7200,2607,63583,50,1250;QS=0.994224,0.00288809,0.00288809,0;VDB=0.32;SGB=-0.453602;RPBZ=-1.01088;MQBZ=0;MQSBZ=0;BQBZ=-2.59034;SCBZ=0.329971;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:110,1,1,0 000000F 552 . A C,<*> 0 . DP=116;I16=60,50,1,1,3927,151331,24,288,6600,396000,120,7200,2598,63352,50,1250;QS=0.993926,0.00607441,0;VDB=0.1;SGB=-0.453602;RPBZ=-1.12079;MQBZ=0;MQSBZ=0;BQBZ=-2.37929;SCBZ=-0.136538;MQ0F=0 PL:AD 0,255,255,255,255,255:110,2,0 000000F 553 . G T,<*> 0 . DP=116;I16=60,51,1,0,4046,158108,12,144,6660,399600,60,3600,2613,63729,25,625;QS=0.997043,0.00295712,0;SGB=-0.379885;RPBZ=-0.35579;MQBZ=0;MQSBZ=0;BQBZ=-1.77886;SCBZ=0.688792;MQ0F=0 PL:AD 0,255,255,255,255,255:111,1,0 000000F 554 . A <*> 0 . DP=113;I16=60,50,0,0,4046,159278,0,0,6600,396000,0,0,2629,64087,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:110,0 000000F 555 . G <*> 0 . DP=112;I16=60,49,0,0,4016,156988,0,0,6540,392400,0,0,2600,63438,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 556 . A <*> 0 . DP=112;I16=60,49,0,0,3915,151463,0,0,6540,392400,0,0,2588,63068,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 557 . A <*> 0 . DP=112;I16=60,49,0,0,3957,151889,0,0,6540,392400,0,0,2575,62681,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:109,0 000000F 558 . A G,<*> 0 . DP=112;I16=60,47,0,2,3726,140280,24,288,6420,385200,120,7200,2510,60980,50,1250;QS=0.9936,0.0064,0;VDB=0.22;SGB=-0.453602;RPBZ=-1.14043;MQBZ=0;MQSBZ=0;BQBZ=-2.29525;SCBZ=-0.444037;MQ0F=0 PL:AD 0,255,255,255,255,255:107,2,0 000000F 559 . C T,<*> 0 . DP=112;I16=59,49,1,0,3985,155617,12,144,6480,388800,60,3600,2518,61092,25,625;QS=0.996998,0.00300225,0;SGB=-0.379885;RPBZ=0.731168;MQBZ=0;MQSBZ=0;BQBZ=-1.78272;SCBZ=-1.08527;MQ0F=0 PL:AD 0,255,255,255,255,255:108,1,0 000000F 560 . T <*> 0 . DP=110;I16=59,48,0,0,3896,150870,0,0,6420,385200,0,0,2507,60841,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:107,0 000000F 561 . G <*> 0 . DP=110;I16=59,48,0,0,3921,153367,0,0,6420,385200,0,0,2492,60440,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:107,0 000000F 562 . T C,A,<*> 0 . DP=110;I16=58,47,1,1,3748,143542,24,288,6300,378000,120,7200,2425,58723,50,1250;QS=0.993637,0.00318134,0.00318134,0;VDB=0.32;SGB=-0.453602;RPBZ=1.03535;MQBZ=0;MQSBZ=0;BQBZ=-2.35872;SCBZ=-0.452888;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:105,1,1,0 000000F 563 . G A,<*> 0 . DP=109;I16=59,45,0,2,3881,153011,24,288,6240,374400,120,7200,2384,57712,50,1250;QS=0.993854,0.00614597,0;VDB=0.06;SGB=-0.453602;RPBZ=-1.81161;MQBZ=0;MQSBZ=0;BQBZ=-2.59069;SCBZ=-0.927311;MQ0F=0 PL:AD 0,255,255,255,255,255:104,2,0 000000F 564 . G <*> 0 . DP=109;I16=59,47,0,0,3954,155218,0,0,6360,381600,0,0,2417,58561,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:106,0 000000F 565 . A G,<*> 0 . DP=108;I16=59,44,0,2,3818,150006,24,288,6180,370800,120,7200,2351,56943,50,1250;QS=0.993753,0.00624675,0;VDB=0.52;SGB=-0.453602;RPBZ=-0.0703536;MQBZ=0;MQSBZ=0;BQBZ=-2.43017;SCBZ=-0.752998;MQ0F=0 PL:AD 0,255,255,255,255,255:103,2,0 000000F 566 . T <*> 0 . DP=108;I16=59,46,0,0,3981,157549,0,0,6300,378000,0,0,2384,57808,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:105,0 000000F 567 . G T,C,<*> 0 . DP=108;I16=57,46,2,0,3847,151871,20,208,6180,370800,120,7200,2318,56254,48,1154;QS=0.994828,0.00310318,0.00206879,0;VDB=0.7;SGB=-0.453602;RPBZ=0.128964;MQBZ=0;MQSBZ=0;BQBZ=-2.74966;SCBZ=-0.146119;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:103,1,1,0 000000F 568 . T C,<*> 0 . DP=106;I16=56,47,1,0,3763,145559,8,64,6180,370800,60,3600,2349,56993,25,625;QS=0.997879,0.00212145,0;SGB=-0.379885;RPBZ=0.983018;MQBZ=0;MQSBZ=0;BQBZ=-1.93576;SCBZ=-1.05631;MQ0F=0 PL:AD 0,255,255,255,255,255:103,1,0 000000F 569 . C G,A,<*> 0 . DP=104;I16=55,45,0,2,3734,146948,24,288,6000,360000,120,7200,2309,55985,50,1250;QS=0.993614,0.00319319,0.00319319,0;VDB=0.58;SGB=-0.453602;RPBZ=-0.543243;MQBZ=0;MQSBZ=0;BQBZ=-2.54989;SCBZ=-1.48352;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:100,1,1,0 000000F 570 . T <*> 0 . DP=104;I16=55,47,0,0,3862,151566,0,0,6120,367200,0,0,2342,56784,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:102,0 000000F 571 . G <*> 0 . DP=104;I16=55,47,0,0,3733,145003,0,0,6120,367200,0,0,2325,56367,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:102,0 000000F 572 . T A,G,<*> 0 . DP=103;I16=53,46,1,1,3664,142548,34,628,5940,356400,120,7200,2259,54733,50,1250;QS=0.990806,0.00594916,0.003245,0;VDB=0.22;SGB=-0.453602;RPBZ=0.219457;MQBZ=0;MQSBZ=0;BQBZ=-2.44659;SCBZ=0.216127;MQ0F=0 PL:AD 0,255,255,255,255,255,255,255,255,255:99,1,1,0 000000F 573 . C G,<*> 0 . DP=103;I16=54,46,0,1,3749,146645,12,144,6000,360000,60,3600,2267,54957,25,625;QS=0.996809,0.00319064,0;SGB=-0.379885;RPBZ=-0.428856;MQBZ=0;MQSBZ=0;BQBZ=-1.85387;SCBZ=-1.03794;MQ0F=0 PL:AD 0,255,255,255,255,255:100,1,0 000000F 574 . A <*> 0 . DP=102;I16=54,46,0,0,3671,141999,0,0,6000,360000,0,0,2275,55165,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:100,0 000000F 575 . A <*> 0 . DP=101;I16=53,46,0,0,3653,142115,0,0,5940,356400,0,0,2259,54781,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:99,0 000000F 576 . C <*> 0 . DP=99;I16=52,45,0,0,3665,144129,0,0,5820,349200,0,0,2229,54203,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 577 . A <*> 0 . DP=99;I16=52,45,0,0,3533,136769,0,0,5820,349200,0,0,2212,53762,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 578 . C <*> 0 . DP=99;I16=52,45,0,0,3593,140361,0,0,5820,349200,0,0,2189,53061,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:97,0 000000F 579 . A <*> 0 . DP=98;I16=51,45,0,0,3516,137036,0,0,5760,345600,0,0,2166,52356,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:96,0 000000F 580 . A <*> 0 . DP=98;I16=51,45,0,0,3569,139629,0,0,5760,345600,0,0,2141,51599,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:96,0 000000F 581 . C <*> 0 . DP=95;I16=49,44,0,0,3512,137782,0,0,5580,334800,0,0,2096,50392,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:93,0 000000F 582 . A <*> 0 . DP=94;I16=49,43,0,0,3411,135315,0,0,5520,331200,0,0,2073,49673,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:92,0 000000F 583 . G C,<*> 0 . DP=90;I16=46,41,1,0,3292,129550,12,144,5220,313200,60,3600,1985,47479,25,625;QS=0.996368,0.00363196,0;SGB=-0.379885;RPBZ=0.334737;MQBZ=0;MQSBZ=0;BQBZ=-1.89321;SCBZ=-1.01118;MQ0F=0 PL:AD 0,245,255,255,255,255:87,1,0 000000F 584 . A <*> 0 . DP=87;I16=45,40,0,0,3152,123280,0,0,5100,306000,0,0,1940,46204,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 585 . A <*> 0 . DP=88;I16=44,40,0,0,3202,127432,0,0,5040,302400,0,0,1914,45520,0,0;QS=1,0;MQ0F=0 PL:AD 0,253,255:84,0 000000F 586 . A G,<*> 0 . DP=88;I16=43,40,1,0,2964,114852,12,144,4980,298800,60,3600,1875,44509,16,256;QS=0.995968,0.00403226,0;SGB=-0.379885;RPBZ=0.866495;MQBZ=0;MQSBZ=0;BQBZ=-1.73561;SCBZ=1.14098;MQ0F=0 PL:AD 0,234,255,250,255,255:83,1,0 000000F 587 . A C,<*> 0 . DP=88;I16=45,40,0,1,2997,115249,12,144,5100,306000,60,3600,1891,44583,25,625;QS=0.996012,0.00398804,0;SGB=-0.379885;RPBZ=-0.584321;MQBZ=0;MQSBZ=0;BQBZ=-1.64438;SCBZ=0.548806;MQ0F=0 PL:AD 0,240,255,255,255,255:85,1,0 000000F 588 . A <*> 0 . DP=87;I16=45,40,0,0,2971,113817,0,0,5100,306000,0,0,1891,44401,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 589 . G A,<*> 0 . DP=87;I16=44,40,1,0,3059,117323,12,144,5040,302400,60,3600,1840,42970,25,625;QS=0.996092,0.00390752,0;SGB=-0.379885;RPBZ=0.550542;MQBZ=0;MQSBZ=0;BQBZ=-1.79452;SCBZ=1.68471;MQ0F=0 PL:AD 0,237,255,253,255,255:84,1,0 000000F 590 . T <*> 0 . DP=87;I16=45,40,0,0,3019,114421,0,0,5100,306000,0,0,1839,42841,0,0;QS=1,0;MQ0F=0 PL:AD 0,255,255:85,0 000000F 591 . G C,<*> 0 . DP=86;I16=43,40,1,0,3033,117015,12,144,4980,298800,60,3600,1807,42121,3,9;QS=0.996059,0.00394089,0;SGB=-0.379885;RPBZ=1.67089;MQBZ=0;MQSBZ=0;BQBZ=-1.80181;SCBZ=-1.01597;MQ0F=0 PL:AD 0,234,255,250,255,255:83,1,0 000000F 592 . A C,<*> 0 . DP=85;I16=44,38,0,2,2821,106231,24,288,4920,295200,120,7200,1748,40690,36,746;QS=0.991564,0.00843585,0;VDB=0.5;SGB=-0.453602;RPBZ=0.484389;MQBZ=0;MQSBZ=0;BQBZ=-2.1998;SCBZ=-0.0922779;MQ0F=0 PL:AD 0,217,255,247,255,255:82,2,0 000000F 593 . C G,A,<*> 0 . DP=84;I16=42,39,1,1,2912,110366,24,288,4860,291600,120,7200,1709,39543,50,1250;QS=0.991826,0.00408719,0.00408719,0;VDB=0.36;SGB=-0.453602;RPBZ=-0.0891287;MQBZ=0;MQSBZ=0;BQBZ=-2.57106;SCBZ=-0.108692;MQ0F=0 PL:AD 0,228,255,228,255,255,244,255,255,255:81,1,1,0 000000F 594 . T <*> 0 . DP=84;I16=43,40,0,0,2911,110919,0,0,4980,298800,0,0,1733,40151,0,0;QS=1,0;MQ0F=0 PL:AD 0,250,255:83,0 000000F 595 . G <*> 0 . DP=82;I16=42,39,0,0,2849,108157,0,0,4860,291600,0,0,1681,38837,0,0;QS=1,0;MQ0F=0 PL:AD 0,244,255:81,0 000000F 596 . A C,<*> 0 . DP=81;I16=42,37,0,1,2846,108902,12,144,4740,284400,60,3600,1613,37303,25,625;QS=0.995801,0.00419874,0;SGB=-0.379885;RPBZ=-0.9748;MQBZ=0;MQSBZ=0;BQBZ=-1.73819;SCBZ=0.250526;MQ0F=0 PL:AD 0,222,255,238,255,255:79,1,0 000000F 597 . T G,<*> 0 . DP=80;I16=42,36,0,1,2742,102116,12,144,4680,280800,60,3600,1574,36614,15,225;QS=0.995643,0.0043573,0;SGB=-0.379885;RPBZ=0.833621;MQBZ=0;MQSBZ=0;BQBZ=-1.70797;SCBZ=0.254296;MQ0F=0 PL:AD 0,219,255,235,255,255:78,1,0 000000F 598 . T <*> 0 . DP=79;I16=41,37,0,0,2839,109553,0,0,4680,280800,0,0,1562,36238,0,0;QS=1,0;MQ0F=0 PL:AD 0,235,255:78,0 000000F 599 . A <*> 0 . DP=77;I16=40,36,0,0,2770,106710,0,0,4560,273600,0,0,1528,35518,0,0;QS=1,0;MQ0F=0 PL:AD 0,229,255:76,0 000000F 600 . G <*> 0 . DP=77;I16=40,36,0,0,2714,103152,0,0,4560,273600,0,0,1498,34792,0,0;QS=1,0;MQ0F=0 PL:AD 0,229,255:76,0 000000F 601 . T G,C,<*> 0 . DP=77;I16=39,35,1,1,2583,97801,24,288,4440,266400,120,7200,1417,32827,50,1250;QS=0.990798,0.00460123,0.00460123,0;VDB=0.1;SGB=-0.453602;RPBZ=-0.795612;MQBZ=0;MQSBZ=0;BQBZ=-2.28816;SCBZ=0.0680273;MQ0F=0 PL:AD 0,207,255,207,255,255,223,255,255,255:74,1,1,0 000000F 602 . T A,C,<*> 0 . DP=74;I16=37,33,1,2,2416,90472,61,1657,4200,252000,180,10800,1357,31631,60,1350;QS=0.975373,0.019782,0.00484457,0;VDB=0.568985;SGB=-0.511536;RPBZ=0.333732;MQBZ=0;MQSBZ=0;BQBZ=-2.13242;SCBZ=0.845379;MQ0F=0 PL:AD 0,164,255,195,255,255,211,255,255,255:70,2,1,0 000000F 603 . A C,<*> 0 . DP=68;I16=35,30,1,0,2312,88408,12,144,3900,234000,60,3600,1347,31297,25,625;QS=0.994837,0.00516351,0;SGB=-0.379885;RPBZ=-0.131301;MQBZ=0;MQSBZ=0;BQBZ=-1.66952;SCBZ=-1.04349;MQ0F=0 PL:AD 0,180,255,196,255,255:65,1,0 000000F 604 . G <*> 0 . DP=67;I16=36,30,0,0,2403,93039,0,0,3960,237600,0,0,1349,31351,0,0;QS=1,0;MQ0F=0 PL:AD 0,199,255:66,0 000000F 605 . A G,<*> 0 . DP=66;I16=35,28,1,1,2254,85780,24,288,3780,226800,120,7200,1292,30038,33,689;QS=0.989464,0.0105356,0;VDB=0.36;SGB=-0.453602;RPBZ=0.589131;MQBZ=0;MQSBZ=0;BQBZ=-2.37279;SCBZ=1.62638;MQ0F=0 PL:AD 0,162,255,190,255,255:63,2,0 000000F 606 . T G,<*> 0 . DP=65;I16=34,29,1,0,2247,87073,22,484,3780,226800,60,3600,1287,29883,13,169;QS=0.990304,0.0096959,0;SGB=-0.379885;RPBZ=1.00206;MQBZ=0;MQSBZ=0;BQBZ=-1.38823;SCBZ=-1.04683;MQ0F=0 PL:AD 0,170,255,190,255,255:63,1,0 000000F 607 . G <*> 0 . DP=64;I16=35,28,0,0,2255,86451,0,0,3780,226800,0,0,1255,29027,0,0;QS=1,0;MQ0F=0 PL:AD 0,190,255:63,0 000000F 608 . T G,<*> 0 . DP=62;I16=33,27,1,0,2177,84023,8,64,3600,216000,60,3600,1182,27240,25,625;QS=0.996339,0.00366133,0;SGB=-0.379885;RPBZ=0.0852552;MQBZ=0;MQSBZ=0;BQBZ=-1.89659;SCBZ=-1.04111;MQ0F=0 PL:AD 0,166,255,181,255,255:60,1,0 000000F 609 . A G,<*> 0 . DP=60;I16=33,25,0,1,2036,77468,12,144,3480,208800,60,3600,1139,26307,25,625;QS=0.994141,0.00585938,0;SGB=-0.379885;RPBZ=-0.0881423;MQBZ=0;MQSBZ=0;BQBZ=-1.68674;SCBZ=1.23654;MQ0F=0 PL:AD 0,160,255,175,255,255:58,1,0 000000F 610 . A <*> 0 . DP=59;I16=33,25,0,0,2025,77505,0,0,3480,208800,0,0,1144,26524,0,0;QS=1,0;MQ0F=0 PL:AD 0,175,255:58,0 000000F 611 . C T,<*> 0 . DP=55;I16=14,12,16,12,990,39320,1009,38281,1560,93600,1680,100800,576,13946,550,12206;QS=0.495248,0.504752,0;VDB=1.84196e-06;SGB=-0.693054;RPBZ=1.75927;MQBZ=0;MQSBZ=0;BQBZ=-0.270305;SCBZ=-0.614376;MQ0F=0 PL:AD 255,0,255,255,255,255:26,28,0 000000F 612 . T <*> 0 . DP=54;I16=29,24,0,0,1898,72790,0,0,3180,190800,0,0,1111,25815,0,0;QS=1,0;MQ0F=0 PL:AD 0,160,255:53,0 000000F 613 . A G,C,<*> 0 . DP=54;I16=27,24,2,0,1946,77058,24,288,3060,183600,120,7200,1046,24258,50,1250;QS=0.987817,0.00609137,0.00609137,0;VDB=0.06;SGB=-0.453602;RPBZ=0.537207;MQBZ=0;MQSBZ=0;BQBZ=-2.67554;SCBZ=0.495445;MQ0F=0 PL:AD 0,139,255,139,255,255,154,255,255,255:51,1,1,0 000000F 614 . A C,<*> 0 . DP=53;I16=28,23,0,1,1870,73000,12,144,3060,183600,60,3600,1054,24458,25,625;QS=0.993624,0.0063762,0;SGB=-0.379885;RPBZ=0.033359;MQBZ=0;MQSBZ=0;BQBZ=-1.88;SCBZ=1.24225;MQ0F=0 PL:AD 0,139,255,154,255,255:51,1,0 000000F 615 . T <*> 0 . DP=53;I16=28,24,0,0,1924,74686,0,0,3120,187200,0,0,1061,24643,0,0;QS=1,0;MQ0F=0 PL:AD 0,157,255:52,0 000000F 616 . T G,<*> 0 . DP=53;I16=28,23,0,1,1815,69225,12,144,3060,183600,60,3600,1017,23565,25,625;QS=0.993432,0.00656814,0;SGB=-0.379885;RPBZ=-0.833529;MQBZ=0;MQSBZ=0;BQBZ=-1.66586;SCBZ=0.352496;MQ0F=0 PL:AD 0,139,255,154,255,255:51,1,0 000000F 617 . T <*> 0 . DP=52;I16=27,24,0,0,1844,70962,0,0,3060,183600,0,0,1024,23774,0,0;QS=1,0;MQ0F=0 PL:AD 0,154,255:51,0 000000F 618 . C <*> 0 . DP=52;I16=27,24,0,0,1782,67390,0,0,3060,183600,0,0,1005,23345,0,0;QS=1,0;MQ0F=0 PL:AD 0,154,255:51,0 000000F 619 . A C,<*> 0 . DP=52;I16=26,24,1,0,1756,66842,12,144,3000,180000,60,3600,961,22329,25,625;QS=0.993213,0.00678733,0;SGB=-0.379885;RPBZ=0.612053;MQBZ=0;MQSBZ=0;BQBZ=-1.58836;SCBZ=1.65684;MQ0F=0 PL:AD 0,136,255,151,255,255:50,1,0 000000F 620 . A <*> 0 . DP=50;I16=25,24,0,0,1670,63616,0,0,2940,176400,0,0,969,22599,0,0;QS=1,0;MQ0F=0 PL:AD 0,148,255:49,0 000000F 621 . C <*> 0 . DP=49;I16=24,24,0,0,1738,67580,0,0,2880,172800,0,0,953,22277,0,0;QS=1,0;MQ0F=0 PL:AD 0,144,255:48,0 000000F 622 . T <*> 0 . DP=47;I16=23,23,0,0,1642,63060,0,0,2760,165600,0,0,921,21681,0,0;QS=1,0;MQ0F=0 PL:AD 0,138,255:46,0 000000F 623 . A G,C,<*> 0 . DP=46;I16=22,21,1,1,1593,61369,24,288,2580,154800,120,7200,862,20368,44,986;QS=0.985158,0.00742115,0.00742115,0;VDB=0.28;SGB=-0.453602;RPBZ=0.110272;MQBZ=0;MQSBZ=0;BQBZ=-2.46441;SCBZ=-0.699329;MQ0F=0 PL:AD 0,116,255,116,255,255,129,255,255,255:43,1,1,0 000000F 624 . T <*> 0 . DP=45;I16=22,22,0,0,1522,57304,0,0,2640,158400,0,0,892,21056,0,0;QS=1,0;MQ0F=0 PL:AD 0,132,255:44,0 000000F 625 . C <*> 0 . DP=43;I16=20,23,0,0,1462,54230,0,0,2580,154800,0,0,905,21409,0,0;QS=1,0;MQ0F=0 PL:AD 0,129,255:43,0 000000F 626 . T A,<*> 0 . DP=42;I16=19,22,0,1,1407,52739,12,144,2460,147600,60,3600,869,20535,25,625;QS=0.991543,0.00845666,0;SGB=-0.379885;RPBZ=0.0826192;MQBZ=0;MQSBZ=0;BQBZ=-1.63079;SCBZ=-0.998652;MQ0F=0 PL:AD 0,110,255,123,255,255:41,1,0 000000F 627 . A <*> 0 . DP=42;I16=19,23,0,0,1458,54660,0,0,2520,151200,0,0,880,20786,0,0;QS=1,0;MQ0F=0 PL:AD 0,126,255:42,0 000000F 628 . G C,<*> 0 . DP=41;I16=17,23,1,0,1491,57863,12,144,2400,144000,60,3600,838,19618,24,576;QS=0.992016,0.00798403,0;SGB=-0.379885;RPBZ=0.296217;MQBZ=0;MQSBZ=0;BQBZ=-1.99912;SCBZ=-0.981384;MQ0F=0 PL:AD 0,107,255,120,255,255:40,1,0 000000F 629 . T <*> 0 . DP=40;I16=18,22,0,0,1452,55272,0,0,2400,144000,0,0,827,19349,0,0;QS=1,0;MQ0F=0 PL:AD 0,120,255:40,0 000000F 630 . C <*> 0 . DP=38;I16=16,22,0,0,1338,50174,0,0,2280,136800,0,0,812,18860,0,0;QS=1,0;MQ0F=0 PL:AD 0,114,255:38,0 000000F 631 . T G,<*> 0 . DP=37;I16=14,22,1,0,1280,48224,32,1024,2160,129600,60,3600,783,18083,11,121;QS=0.97561,0.0243902,0;SGB=-0.379885;RPBZ=1.36088;MQBZ=0;MQSBZ=0;BQBZ=-1.06419;SCBZ=-0.906765;MQ0F=0 PL:AD 0,79,255,108,255,255:36,1,0 000000F 632 . T <*> 0 . DP=36;I16=15,21,0,0,1320,50548,0,0,2160,129600,0,0,761,17359,0,0;QS=1,0;MQ0F=0 PL:AD 0,108,255:36,0 000000F 633 . C A,<*> 0 . DP=35;I16=14,19,0,2,1183,44803,24,288,1980,118800,120,7200,678,15322,47,1109;QS=0.980116,0.019884,0;VDB=0.26;SGB=-0.453602;RPBZ=0.463397;MQBZ=0;MQSBZ=0;BQBZ=-2.3085;SCBZ=1.47371;MQ0F=0 PL:AD 0,76,255,99,255,255:33,2,0 000000F 634 . C <*> 0 . DP=35;I16=14,21,0,0,1290,49572,0,0,2100,126000,0,0,708,15898,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 635 . T <*> 0 . DP=35;I16=14,21,0,0,1242,47888,0,0,2100,126000,0,0,691,15399,0,0;QS=1,0;MQ0F=0 PL:AD 0,105,255:35,0 000000F 636 . C T,<*> 0 . DP=34;I16=13,20,1,0,1163,44105,12,144,1980,118800,60,3600,643,14453,16,256;QS=0.989787,0.0102128,0;SGB=-0.379885;RPBZ=0.66524;MQBZ=0;MQSBZ=0;BQBZ=-1.57615;SCBZ=-0.84147;MQ0F=0 PL:AD 0,87,255,99,255,255:33,1,0 000000F 637 . T <*> 0 . DP=33;I16=14,19,0,0,1151,43717,0,0,1980,118800,0,0,627,14033,0,0;QS=1,0;MQ0F=0 PL:AD 0,99,255:33,0 000000F 638 . A <*> 0 . DP=32;I16=13,19,0,0,1113,41153,0,0,1920,115200,0,0,605,13531,0,0;QS=1,0;MQ0F=0 PL:AD 0,96,255:32,0 000000F 639 . A T,<*> 0 . DP=30;I16=13,16,0,1,965,34529,12,144,1740,104400,60,3600,577,12917,13,169;QS=0.987718,0.0122825,0;SGB=-0.379885;RPBZ=0.988773;MQBZ=0;MQSBZ=0;BQBZ=-1.63451;SCBZ=-0.878553;MQ0F=0 PL:AD 0,75,255,87,255,255:29,1,0 000000F 640 . A <*> 0 . DP=29;I16=12,17,0,0,994,36924,0,0,1740,104400,0,0,575,12621,0,0;QS=1,0;MQ0F=0 PL:AD 0,87,255:29,0 000000F 641 . G T,<*> 0 . DP=27;I16=11,15,0,1,869,31995,12,144,1560,93600,60,3600,529,11623,11,121;QS=0.986379,0.0136209,0;SGB=-0.379885;RPBZ=1.35554;MQBZ=0;MQSBZ=0;BQBZ=-1.5086;SCBZ=-0.793551;MQ0F=0 PL:AD 0,66,255,78,255,255:26,1,0 000000F 642 . A C,<*> 0 . DP=26;I16=11,14,0,1,850,31010,22,484,1500,90000,60,3600,504,11078,9,81;QS=0.974771,0.0252294,0;SGB=-0.379885;RPBZ=1.41458;MQBZ=0;MQSBZ=0;BQBZ=-1.18957;SCBZ=0.532911;MQ0F=0 PL:AD 0,56,255,75,255,255:25,1,0 000000F 643 . C <*> 0 . DP=26;I16=11,15,0,0,912,34334,0,0,1560,93600,0,0,499,10747,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 644 . C A,<*> 0 . DP=26;I16=11,14,0,1,869,31707,12,144,1500,90000,60,3600,464,9914,20,400;QS=0.986379,0.0136209,0;SGB=-0.379885;RPBZ=0.268045;MQBZ=0;MQSBZ=0;BQBZ=-1.6731;SCBZ=0.989693;MQ0F=0 PL:AD 0,63,255,75,255,255:25,1,0 000000F 645 . C <*> 0 . DP=26;I16=11,15,0,0,911,33421,0,0,1560,93600,0,0,466,9764,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 646 . C <*> 0 . DP=26;I16=11,15,0,0,850,29718,0,0,1560,93600,0,0,447,9201,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 647 . T C,<*> 0 . DP=26;I16=11,14,0,1,898,34076,12,144,1500,90000,60,3600,423,8651,5,25;QS=0.986813,0.0131868,0;SGB=-0.379885;RPBZ=1.14097;MQBZ=0;MQSBZ=0;BQBZ=-1.57982;SCBZ=-0.760963;MQ0F=0 PL:AD 0,63,255,75,255,255:25,1,0 000000F 648 . A <*> 0 . DP=26;I16=11,15,0,0,870,32110,0,0,1560,93600,0,0,407,8091,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 649 . C <*> 0 . DP=26;I16=11,15,0,0,928,35102,0,0,1560,93600,0,0,386,7548,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 650 . T C,<*> 0 . DP=26;I16=11,14,0,1,897,33867,12,144,1500,90000,60,3600,359,6973,5,25;QS=0.986799,0.0132013,0;SGB=-0.379885;RPBZ=0.874779;MQBZ=0;MQSBZ=0;BQBZ=-1.67266;SCBZ=-0.760963;MQ0F=0 PL:AD 0,63,255,75,255,255:25,1,0 000000F 651 . T <*> 0 . DP=26;I16=11,15,0,0,905,33255,0,0,1560,93600,0,0,342,6492,0,0;QS=1,0;MQ0F=0 PL:AD 0,78,255:26,0 000000F 652 . T <*> 0 . DP=25;I16=11,14,0,0,891,32693,0,0,1500,90000,0,0,321,6029,0,0;QS=1,0;MQ0F=0 PL:AD 0,75,255:25,0 000000F 653 . A <*> 0 . DP=21;I16=9,12,0,0,804,31130,0,0,1260,75600,0,0,303,5555,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 654 . A <*> 0 . DP=21;I16=9,12,0,0,659,22061,0,0,1260,75600,0,0,285,5117,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 655 . C <*> 0 . DP=21;I16=9,12,0,0,664,22342,0,0,1260,75600,0,0,266,4666,0,0;QS=1,0;MQ0F=0 PL:AD 0,63,255:21,0 000000F 655 . CACAATACAA CACAA 0 . INDEL;IDV=6;IMF=0.285714;DP=21;I16=0,2,5,1,240,28800,720,86400,120,7200,360,21600,46,1060,100,1788;QS=0.25,0.75;VDB=0.00189453;SGB=-0.616816;RPBZ=-2.81289;MQBZ=0;MQSBZ=0;BQBZ=-1.67266;SCBZ=-2.52262;MQ0F=0 PL:AD 67,0,14:2,6 000000F 656 . A <*> 0 . DP=11;I16=4,7,0,0,404,15690,0,0,660,39600,0,0,141,2411,0,0;QS=1,0;MQ0F=0 PL:AD 0,33,255:11,0 000000F 657 . C <*> 0 . DP=11;I16=4,7,0,0,413,15607,0,0,660,39600,0,0,131,2189,0,0;QS=1,0;MQ0F=0 PL:AD 0,33,255:11,0 000000F 658 . A <*> 0 . DP=10;I16=3,7,0,0,121,1651,0,0,600,36000,0,0,122,1986,0,0;QS=1,0;MQ0F=0 PL:AD 0,30,79:10,0 000000F 658 . AA AAATTA 0 . INDEL;IDV=7;IMF=0.4375;DP=16;I16=0,1,5,2,100,10000,700,70000,60,3600,420,25200,25,625,110,1820;QS=0.235294,0.764706;VDB=0.000272497;SGB=-0.636426;RPBZ=-1.70026;MQBZ=0;MQSBZ=0;BQBZ=-1.67266;SCBZ=-1.35678;MQ0F=0 PL:AD 81,0,16:1,7 000000F 659 . A <*> 0 . DP=10;I16=3,5,0,0,86,1088,0,0,480,28800,0,0,75,1077,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,63:8,0 000000F 660 . T <*> 0 . DP=2;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL:AD 0,0,0:0,0 000000F 661 . A <*> 0 . DP=8;I16=0,2,0,0,8,32,0,0,120,7200,0,0,26,340,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,7:2,0 000000F 662 . C <*> 0 . DP=8;I16=0,2,0,0,10,50,0,0,120,7200,0,0,24,290,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,9:2,0 000000F 663 . A <*> 0 . DP=8;I16=5,3,0,0,40,224,0,0,480,28800,0,0,107,1627,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,24:8,0 000000F 664 . A <*> 0 . DP=8;I16=5,3,0,0,94,1646,0,0,480,28800,0,0,99,1421,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,69:8,0 000000F 665 . A <*> 0 . DP=8;I16=5,3,0,0,165,3551,0,0,480,28800,0,0,91,1231,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,124:8,0 000000F 666 . T <*> 0 . DP=8;I16=5,3,0,0,269,9361,0,0,480,28800,0,0,83,1057,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,207:8,0 000000F 667 . T <*> 0 . DP=8;I16=5,3,0,0,279,10001,0,0,480,28800,0,0,75,899,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,214:8,0 000000F 668 . A <*> 0 . DP=8;I16=5,3,0,0,278,10018,0,0,480,28800,0,0,67,757,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,214:8,0 000000F 669 . C <*> 0 . DP=8;I16=5,3,0,0,279,10051,0,0,480,28800,0,0,59,631,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,214:8,0 000000F 670 . A <*> 0 . DP=8;I16=5,3,0,0,287,10675,0,0,480,28800,0,0,51,521,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,220:8,0 000000F 671 . T <*> 0 . DP=8;I16=5,3,0,0,264,9116,0,0,480,28800,0,0,43,427,0,0;QS=1,0;MQ0F=0 PL:AD 0,24,205:8,0 000000F 672 . C <*> 0 . DP=7;I16=4,3,0,0,237,8337,0,0,420,25200,0,0,36,348,0,0;QS=1,0;MQ0F=0 PL:AD 0,21,193:7,0 000000F 673 . T <*> 0 . DP=7;I16=4,3,0,0,223,7385,0,0,420,25200,0,0,29,283,0,0;QS=1,0;MQ0F=0 PL:AD 0,21,181:7,0 000000F 674 . A <*> 0 . DP=6;I16=4,2,0,0,199,6757,0,0,360,21600,0,0,23,231,0,0;QS=1,0;MQ0F=0 PL:AD 0,18,164:6,0 000000F 675 . G <*> 0 . DP=4;I16=2,2,0,0,147,5443,0,0,240,14400,0,0,19,189,0,0;QS=1,0;MQ0F=0 PL:AD 0,12,134:4,0 000000F 676 . A <*> 0 . DP=3;I16=2,1,0,0,100,3434,0,0,180,10800,0,0,16,154,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,95:3,0 000000F 677 . T <*> 0 . DP=3;I16=2,1,0,0,104,3846,0,0,180,10800,0,0,13,125,0,0;QS=1,0;MQ0F=0 PL:AD 0,9,100:3,0 000000F 678 . A <*> 0 . DP=2;I16=1,1,0,0,53,1825,0,0,120,7200,0,0,11,101,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,53:2,0 000000F 679 . T <*> 0 . DP=2;I16=1,1,0,0,68,2410,0,0,120,7200,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:AD 0,6,68:2,0 000000F 680 . T <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,41:1,0 000000F 681 . T <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,41:1,0 000000F 682 . G <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,41:1,0 000000F 683 . T <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,35:1,0 000000F 684 . T <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,31:1,0 000000F 685 . A <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,29:1,0 000000F 686 . T <*> 0 . DP=1;I16=0,1,0,0,3,9,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:AD 0,3,4:1,0 000000F 687 . N <*> 0 . DP=1;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL:AD 0,0,0:0,0 000000F 688 . N <*> 0 . 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G <*> 0 . DP=68;I16=6,62,0,0,2437,87909,0,0,3770,217210,0,0,838,15940,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 11 75 . GTAAAATAAAATAAAATAAAATAAA GTAAAATAAAATAAAATAAAATAAAATAAA 0 . 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ATCTATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGT @?D?ABGBDCCDHIDCCCDCHCFGDCDHBDDHBGFCDBIDGCCEGDGACCHCDBBCCHEDGABADCDCBFBB@AA X0:i:1 X1:i:0 MC:Z:75M BD:Z:ONOMRRONNNOPPPMMLBLOLKMMLNLKALMNMLNOKNLNNKKLLLKAJLMKAAJMNNLKKBBLLLLLNNQPNLL PG:Z:MarkDuplicates BI:Z:QPQPUUSQRRSQRRPPPHORPNPPOPONGNOPPPOQMQNQQONONONGNPPOGFMPQPONNGGNOPPOPPSQQNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2105:2462:26845#86 83 11 3 60 75M * 3 -221 TCTATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTA >C9?@<@ABC6-FA;GCADHBA?I-BGCI?CBFCA.>:ECCDH?7=BCB/DEGA2A@?BA@C@DB??> X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MNMNSOOOOQPPPNNMCLOLKNNMNMLCLMNMNNOLOMOOLLMMMLCLNOLCCLNOPMMMEEMNNNNOPRSNNKK PG:Z:MarkDuplicates BI:Z:PQPQVSRSRSRRSQQQIPSQOQPQQPOHOPQQQPRORPRRPOPPPOHNQQQIIORSRQPPIIPQQQQRRTSQPNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:@;@ X0:i:1 X1:i:0 MC:Z:75M 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XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CG MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2204:7014:42933#86 1171 11 5 60 75M * 5 -220 TATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAA <>@D@BABFHIDCDBDCIAFGACBICCCHBFGBHBHDHDCCFDHBCEHDCCDACIEDHABADBCBCHCGCB><>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:MNOLPPOQPPOMMLCLNKJMMLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLMOOOOKDKK PG:Z:MarkDuplicates BI:Z:PQRPSSSSRRSQPPHORPNQPOPONGNOPOONPMPNPPNMNNONFLOPOGFMPPOOMNGGNOOONPPRQRQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CF MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2209:8848:15365#86 83 11 5 60 75M * 5 -135 TATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAA =?>D?CBDDHICCDCCBIBFGDCDHDDDICGGDHBICIDCCHBIDDGHEDCDCCIDGHABBDBECCHCHEC?<>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MNOLPPPQQQPNNMDMOLKNNMNMLCLMNMNNOLOMOOLLMMMLCLNOLCCLNOPMLLEEMNNMMOOQRQRKDKK PG:Z:MarkDuplicates BI:Z:PQRPSSSTRSTQQQIPSQORQPQQOHOPQQQPRORPRRPOPPPOHNQQPHIORSRQPPIIPQQQPQRTSSROHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CG MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2310:12685:29421#86 147 11 5 60 75M * 5 -164 TATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAA <>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:MNOLPPOQPPOMMLCLNKJMMLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLMOOOOKDKK PG:Z:MarkDuplicates BI:Z:PQRPSSSSRRSQPPHORPNQPOPONGNOPOONPMPNPPNMNNONFLOPOGFMPPOOMNGGNOOONPPRQRQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CF MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2303:2159:28551#86 147 11 5 60 75M * 5 -193 TATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAA >??C@BBCDGGCDDBDCHCFGCCDIDDCGCGGAGCGCGCDCFCGCDEEEADBDBGDDGBBBCCCCCGCFEC>=>A X0:i:1 X1:i:0 MC:Z:75M BD:Z:MOPMPOOPQQPMMMCMOLKMMLNMLBKLMMMNOJOMONKKLLLKAJLMKAAJMNNLKKBBKKKLLMMOPNOLDLL PG:Z:MarkDuplicates BI:Z:PQRPSSSTRSSQQPHORPNQPPPPNGNOPPPOQMQNQQONONONGNPPOGGMPPPONNGGNOOONPORQRQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CG MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1206:15013:37909#86 83 11 6 60 75M * 6 -131 ATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAA ?>EA X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:NOLLQPRQQQNNMDMPLKNNMNMLCLMNMNNOLOMOOLLMMMLCLNOLCCLNOPMLLDEMNNMMNOQQQQODDKK PG:Z:MarkDuplicates BI:Z:QRPOTSTSSTRQQIPSQORQQQPPHOPQQQPRORPRRPOPPPOHNQQPHHORSRQPPIIPQQQPQQTSSRQHHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2204:12873:75746#86 147 11 6 29 5S22M1D5M1I9M1D33M * 6 -261 TACCAATCAATATGCATATTTAAATTACTTTCTTAGTCCCTCTTTTTTTTGATTTTACTGGAAAATATTCTCAGT >3%:(9,0A.,.:60.?.DC,'B.*63/3DC/3,;@87-/,/(B3(()CCHCDDCBCHEDGABADCDBBFBB@AA MC:Z:75M BD:Z:OMNMPQRNNNMOPPPMLLBKKCLLKNNKALMLKLMNLGLLLKAAAAAAJLMKAAJMNNLKKBBLLLLLNNQPNLL PG:Z:MarkDuplicates BI:Z:QPPPSTURQRQSQQRPPPHNOHNPMPQNGNONMPPONINNONGGGGGGNPPOGFMPQPONNGGNOPPOPPSQQNN AM:i:29 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@PO@@KG@@@@@@@GaRGG@UR@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:16C2G2^T10A3^A2C1C28 NM:i:8 RG:Z:rg HS29_09125:3:2210:7730:28099#86 83 11 6 60 75M * 6 -147 ATCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAA ?>A;>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:OPMMQPQRQQNNMCMPMLNNMNMLBMMNMMNOKOMOOLLMMMLBKMNLBBKNOOMLLDDMMMMNOOQRPQODDLL PG:Z:MarkDuplicates BI:Z:QRPOTSTRSSQQPHORPNQPPQPOHOPQQQPRNRORRPPPOPOHOQQQHIORSRQPPIIPQQQPQQTSSRRHHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:B@@DDFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1306:3309:3794#86 83 11 7 60 75M * 7 -116 TCAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAAT ?D=??BDGHCCDDCBIBAHCBEHDDDGCFHCIAHDICDDECDBDFHDCDCBCHEFHBACCCDCDHCHGGA?=?@BCGHCDCBBCBDEHDCCIDCDHDFFDICIDHDCDIDHCBFGDDBDCBIFDGB@ADBDBDHCIEFBA>=?A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:PMMMQRRRQNNNCMPMLNNMOMLBLNNMMNOKOMOOLLMMMLBKMNLBBKNOOMLLCDMMMMMOOQQPPOGDMLL PG:Z:MarkDuplicates BI:Z:RPOPTURSTQQQHORPNQPPQPOHOPQQQPRNRORRPOQOPOHOQQPIHORSRQPPIIPQQQPQPTSSRQKHONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1113:5969:97493#86 147 11 8 60 75M * 8 -182 CAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATA AEF?BAECBCEBDGBH;EBHADBABD:BDECAD?>9HEDH@A@@=BBBGCHCE>>7=>>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:LLMMSRQQNNLCLOLKMMLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNNNKEELMKK PG:Z:MarkDuplicates BI:Z:POPPUSTTRQQIORPNQPPQPNGNOPPPOPMPNPPNMNNNMFMPONFGMPPPOMMGFNOOONOOQQQPOIIOPNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1302:19826:93046#86 147 11 8 60 75M * 8 -268 CAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATA A<@>=>=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:LLMMSRQQNNLCLOLKMMLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNNNKEELMKK PG:Z:MarkDuplicates BI:Z:POPPUSTTRQQIORPNQPPQPNGNOPPPOPMPNPPNMNNNMFMPONFGMPPPOMMGFNOOONOOQQQPOIIOPNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2103:15310:53809#86 83 11 8 60 75M * 8 -242 CAATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATA @=?>ADHHEBDDDCIBFHBDCICDDICDGDIAJBGDBBHBHDCDHDCCCBCGEEHABABADCCICEEHBA?>>>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:LLMMSRRQOOMDMPMLNNMNMLCLMNMNNOLOMOOLLMMMLCLNOLCCLNOPMLLDDLNNMMNNPQPPNGHLMKK PG:Z:MarkDuplicates BI:Z:POPPUSTURRRIPSQORQQRQOHPPQQQPRORPRRPOPPPOHNQQPHHNQSRQPPIIPQQQPQQSRSRQJJOPNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:C@CFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1103:18569:10072#86 147 11 9 29 75M * 9 -178 AATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAA =?C=BBDD>CGBBCIABBI?CF@IAE@DCCDABECCDGBBD?CCFE@H@AAAADCBHBHDF?>?>?<=@ X0:i:1 X1:i:0 MC:Z:64M11S BD:Z:LMMOSRQONMCLOLKNMLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMNKDEMMKKK PG:Z:MarkDuplicates BI:Z:OPPQTTURRQIPRPNQPPQPOGNOPPPOQMPNPPNMNNNMFLPPNFFMPQOONMFGMOOONOOQPQPOHIPPONN AM:i:29 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1305:12077:73234#86 1107 11 9 60 75M * 9 -214 AATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAA >>;?BEDCDCDBDIBDGCDCDCCDICGGCICIBEDCCHBHCCEDDDEDBCIDFHBBBDACCCIBHFF?AA?@;>??G@;D;8BF>@B@BBDBB=H?FBCDACBDAC@DAIC:CC?7BA@AHD4HB;ACECED@9@>>?7>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:LMMOSRQONMCLOLKNMLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMNKDEMMKKK PG:Z:MarkDuplicates BI:Z:OPPQTTURRQIPRPNQPPQPOGNOPPPOQMPNPPNMNNNMFLPPNFFMPQOONMFGMOOONOOQPQPOHIPPONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:1112:13478:14824#86 83 11 9 60 75M * 9 -214 AATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAA >???@FFCCCBCDHBFHBDDHADDHDHHDIDIDIDCDHDIDCFGDBDDCCHDEHBBBECDCDGDHEHCAA@@>>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MMMOTSRONNDNPMLNNMONMBLMNNMNOKOMOOLLMMMLBKMNLBBKNOOMLLCCLMMMMNNQQOONFGPMLLL PG:Z:MarkDuplicates BI:Z:OPPRTTTRRQIPRPNQPPQPOHOPQQQPRNRORRPOPOQOHOQQPHHOQSRQPPIIPQQQPQPSRSRQJJRPONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:1209:8399:89906#86 147 11 9 60 75M * 9 -187 AATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAA ABFFCBEBBDIAEGCECHACCIDEGCHCHDGCDDHCIDCEGCCBBECHDEG@CBCACCCHCHEFC@@@?=>A X0:i:1 X1:i:0 MC:Z:75M BD:Z:MMMOSRRNNNCMPMLNMLNMLBLMNMLMNKOMONLLMLLKAJLMKAAJMNNLKKBBKKKKKLLOOMMKDDNMLLL PG:Z:MarkDuplicates BI:Z:OPPRTTURRRIPSPNQPPQPOHNPPPPOQMQNQQONONONGNPPOGGMPQPONMGGNOOONONQPQPOHIPPONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1211:11085:98311#86 1171 11 10 60 75M * 10 -216 ATATGCATATTTCAAGTATTTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAA ?;?=EDA@>BBBHAEFB@4@BB@D@FEBD@HBICABCB:CCCHC@B?CADBCCB9BC@CB?ECEE@AA??@>;>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:MMOOSROOMDLOLKNNLKBBBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMKDDMNKDKK PG:Z:MarkDuplicates BI:Z:PPQPUUSRRIPSPNQPPPHHHNOPPPOQNPNPPNMNNNMFLOPOFFLPQPNNNFFNNOONOOQPPPOHHPQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CF MD:Z:19C55 NM:i:1 RG:Z:rg HS23_09099:8:2111:1775:55141#86 147 11 10 60 75M * 10 -216 ATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAA ?;??FGC@C>ABEBEHBCAIBABHBFGBH@@CCDCBEBHCAC8C@BD>CFEFGAB@D;=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:MMOOSROOMDLOLKNNLMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMKDDMNKDKK PG:Z:MarkDuplicates BI:Z:PPQPUUSRRIPSPNQPPQPOHNOPPPOQNPNPPNMNNNMFLOPOFFLPQPNNNFFNNOONOOQPPPOHHPQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BF MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:1112:11415:25078#86 147 11 10 60 75M * 10 -251 ATATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAA @?@BCFDCDCBCIBEFCCDGCDCHDGFDGBGCIEBDHCIDDEGECCCAEFDDHCAADCCBCGDGFFCB@@B?=>A X0:i:1 X1:i:0 MC:Z:75M BD:Z:MMOPSRONNDMPMLNNLNMLBLMNMMMNJOMOOKLMMLKAJLMKAAJMNNLKKBBKKKKKLLNOMMKCDMNLDLL PG:Z:MarkDuplicates BI:Z:PPRPUUSRRJPSQNQPPQPOHOOQPPOQMQNQQONONONGNPPOGGMPQPONNFGNOOONONQPPPOHHPQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CG MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1114:9343:40821#86 147 11 11 60 75M * 11 -143 TATGCATATTTCAAGTATCTTTCTAGTCTCTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAA >=AAEFCC@0CABI>D7BC7D6;/B=;A:BCD975B7CABDF:>B3DAABDD@GDFBA8?A><;=? X0:i:1 X1:i:0 MC:Z:75M BD:Z:MOOOSPONDMOLKNNMMLKBKLMLMMLLLLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJDDLNLDDKK PG:Z:MarkDuplicates BI:Z:PQPQVSSRJPSQNQPPQPOHOOPPPOOOONPPNMNNNMFLOOOGFLOQPOMNGFMONONOOQPPOOHHOQPHHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:28A46 NM:i:1 RG:Z:rg HS23_09099:8:2113:11100:46124#86 147 11 11 60 75M * 11 -236 TATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAA ADBABCBBIAEFCBCHBCBEBFGBEAHAICCCH@EACEGBBBBCAIDCGBABCADBCHBGEF@AA@A>><>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:MOOOSPONDMOLKNNMMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJDDLNLDDKK PG:Z:MarkDuplicates BI:Z:PQPQVSSRJPSQNQPPQPOHOOPPPOQNQNPPNMNNNMFLOOOGFLOQPOMNGFMONONOOQPPOOHHOQPHHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2211:11959:71865#86 1171 11 11 60 75M * 11 -298 TATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAA ==@?DBABBBBCFBCBFAFGAEB@AIDA>D@HCBEEDBBBCAIBFG>ABBABBCE@EEF@A@@A>><=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:MOOOSPONDMOLKNNMMLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJDDLNLDDKK PG:Z:MarkDuplicates BI:Z:PQPQVSSRJPSQNQPPQPOHOOPPPOQNQNPPNMNNNMFLOOOGFLOQPOMNGFMONONOOQPPOOHHOQPHHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2213:18250:41219#86 1107 11 11 60 75M * 11 -163 TATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAA =>ADFBACECDIBGHBDDIDCEHCGHCICIDIECCIBFCCEHDDDCBCJEFHBBBDCDDDICIFGCABAC?>@CECDABBDHAGGCFCIDCDIBFHEHDHDIDDDHDIDDFGDBCCDBHFEGCBBCCECCHDGFGBCBACB>=>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MOPPTPOODNQNLNNMONMCMMNMMOOKOMOOLLMMMLBKMNLBBKNOOMLLCCLLLMMNNPPOOMEFOPODDLL PG:Z:MarkDuplicates BI:Z:PRPQVSRRJPSQNQPPQPOHOPQQQPRNRORRPOPOPOIOQQPHHNQSQQPPIIPQQQPQPSRRQQJJQRRHHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2105:8316:18217#86 1107 11 11 60 75M * 11 -163 TATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAA >>AAEBCCDCBHCEGCDAIDCBIDFHEHBHDGDDDHDHDDFGDBBCDDI>EGCCBCCCBCHDGFGBCBAC@>=>6 X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MOPPTPOODNQNLNNMONMCMMNMMOOKOMOOLLMMMLBKMNLBBKNOOMLLCCLLLMMNNPPOOMEFOPODDLL PG:Z:MarkDuplicates BI:Z:PRPQVSRRJPSQNQPPQPOHOPQQQPRNRORRPOPOPOIOQQPHHNQSQQPPIIPQQQPQPSRRQQJJQRRHHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:C@CFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2109:3388:19777#86 83 11 11 60 75M * 11 -163 TATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAA ?;AAEBCCDCDHAFGCDCIDCDIDEGEIDIDIDDDHCHCDFGDBCCDDIFEGCCBCCECDHDGFGBCAACB>=>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MOPPTPOODNQNLNNMONMCMMNMMOOKOMOOLLMMMLBKMNLBBKNOOMLLCCLLLMMNNPPOOMEFOPODDLL PG:Z:MarkDuplicates BI:Z:PRPQVSRRJPSQNQPPQPOHOPQQQPRNRORRPOPOPOIOQQPHHNQSQQPPIIPQQQPQPSRRQQJJQRRHHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CBCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2110:19889:15970#86 1171 11 12 60 75M * 12 -169 ATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAAT ??DBB;BAB5HBEHADCE<@AF6CGCI@ABHDCAH>CBA:?>ABB7BGBFCAABBCC=8BAEDD74A@A:><;@; X0:i:1 X1:i:0 MC:Z:75M BD:Z:OOOOQPNEMPLKNNMNLKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCDLMLEDLKK PG:Z:MarkDuplicates BI:Z:QPQRTSSJQSQOQPPQPOHOPPPPOQNQOPPNMNNNMFLOONGGLOPPONMGGMNONNOOQPPONHHOPPIHONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2205:3471:91058#86 147 11 12 60 75M * 12 -169 ATGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAAT ?@DD@ACADBIBGEADBIBCCHAFFCICHCHDBAICEBADHBDBBBADEFH?BBDADDBGBHEFAAA@B?>>6BBBCBABGBF:CCDGD8CGDGGDIDHCI=?/ X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:OPPPQPOENQNMNNMONMCMNNMMNPKOMOOLLMMMLBKMNLBBKNOOMLLCCLLLLMNNPPNOMEEOOOGDMLL PG:Z:MarkDuplicates BI:Z:RPQRTSRJQSQOQPPQPOHOPQQQPRNRORRPOPOPOHPQQPHHNQRRPPPIIPQQQPQPSRRQPJJQRQKHONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:B@@DDDDF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1112:11826:90589#86 147 11 13 60 75M * 13 -184 TGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATA ?@D>@ABA=C@FHACEHBCAI?FFCHAHBIACBDCDDBDEBCBC@AIEFHBBADBBBBHCFFEAA@AB@?>>>=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:OOOMQOENPMKNNMNMKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCLMKEELMKK PG:Z:MarkDuplicates BI:Z:PQRPTSKQTQORPPQPOHOPQPPOQNQOQPNMNNNMFLOONFGMOPOONNFGNNNOMOOQPPONGHOPOIIOPNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2302:3414:63664#86 147 11 13 60 75M * 13 -162 TGCATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATA @CD?>ABADIAGHCCBHCCBIAFFBEAIBHC=CICHDBDHDCCABBIEFGBBBDCCBDHDHFGBAAAC@??=>=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:OOOMQOENPMKNNMNMKBKLMLMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCLMKEELMKK PG:Z:MarkDuplicates BI:Z:PQRPTSKQTQORPPQPOHOPQPPOQNQOQPNMNNNMFLOONFGMOPOONNFGNNNOMOOQPPONGHOPOIIOPNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2315:3893:3642#86 83 11 15 60 75M * 15 -231 CATATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAA D?=>ABCICIDDDFDHACCH@CAA@CHEFHBBBCC>DCIBJEEAAAAB@B=?A?<>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:OMMLGORNMPONONMDLMNMNNOLOMOOLLMMMLCLNOLCCLNOPMLLDDLMMLLMMOPOOLEEMOMFGOQKDKK PG:Z:MarkDuplicates BI:Z:RPPPLRUSPSRQRQPIPQRRRPRPRPRRPOPPPOHNQQPHHNQRQPOOHHPQQQPQQSRRQPIIPQQJJQROHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:@@@DDDDA XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CG MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1213:6595:86362#86 83 11 17 60 75M * 17 -214 TATTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAAT =?=?AG@EGBDDI?DCFCGGCIBIBIDACICIABFHCBBCB?IEEHBBBDBCDBICIEGABABDAAAACA?>AFBEFCECIBCCIBCHCGDICHFBDIDIDDEHDBDCDBIDEHCCCDDCDDGCHGFDACADCABBCB@>=?A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MMCMTPNPONPOMCMNONNOPKOMOPLLMMMLBKMNLBBKNOOMLLCCLLLLLMMOONNLDDMNMEEOOOGDMLL PG:Z:MarkDuplicates BI:Z:PPHOVSPSRQRQOHOPQQQPRNRORRPOPOPOHOQQPHINQRQPOOHIOQQQPQPSRRQPIIPQPJJQRQKHONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:C@BFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1311:4657:33709#86 1171 11 19 60 75M * 19 -161 TTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAA >=>D@EF@>BIDBDHAFDCIAHCECCCIBICAEHCCDBCAICEHAAADCCADIADEFCAAACB@AAA@@?>@<>@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:CLOLOQPOONLCLMNMMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKMKDEMMKKK PG:Z:MarkDuplicates BI:Z:HORPRTSRSQPIOPQQQPROROQQONOOOMFLOONFFLOPONNNFFMOOOMOOPOPNNGGNONGGOPOHIPPONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2104:1810:83836#86 147 11 19 60 75M * 19 -218 TTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAA 4>>;@EA5>:DCC4<7A?@B0BE2CC=?CDBABF>@G>@>B7CABD8EDD6)BBB+6AAA?@?>@<=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:CLOLOQPOONLCLMNMMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKMKDEMMKKK PG:Z:MarkDuplicates BI:Z:HORPRTSRSQPIOPQQQPROROQQONOOOMFLOONFFLOPONNNFFMOOOMOOPOPNNGGNONGGOPOHIPPONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2301:19435:90711#86 1171 11 19 60 75M * 19 -161 TTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAA ;9=?>AF5CCDCA0;=DDCI=B7@>AC9<=>@:>; X0:i:1 X1:i:0 MC:Z:75M BD:Z:CLOLOQPOONLCLMNMMMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKMKDEMMKKK PG:Z:MarkDuplicates BI:Z:HORPRTSRSQPIOPQQQPROROQQONOOOMFLOONFFLOPONNNFFMOOOMOOPOPNNGGNONGGOPOHIPPONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2304:10091:65056#86 83 11 19 60 75M * 19 -161 TTTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAA ?>=D?DGAECIDDCIBFHDIBI?IDDCICIDCFGDCCCCBIDFHBBBDBDCDIBIGHCCBBDBDABCCAA?@<>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:CLOLOQQOPOMDMNONNNOLOMOOLLMMMLCLNOLCCLNOPMLLDDLMMLLMMOONNKEEMNLEENOMGGPMKKK PG:Z:MarkDuplicates BI:Z:HORPRTSSSRQIPQRRRQSPSPRSPOPPPOHNQQPHHNQRQPOOHHOPPPPQQSRRQPIIPQPIIPRQJJQPONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCBFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1203:17737:83552#86 147 11 20 60 75M * 20 -205 TTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAA >>D=DF>BBG@<<=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:LOLKRQOPNMCLMNMNMNKNLNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKLKDDMNKDKK PG:Z:MarkDuplicates BI:Z:ORPNUSSSRPIPPQQQPRORPQQONOOONFLOONFFLOPONMNGFMNOONNOQOOOMGGNONGGNPOHHPQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BF MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:1113:12454:76493#86 83 11 20 60 75M * 20 -349 TTCAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAA ?>B=CFACBFDCDHCEECIDHBIDCDHDICCFHDCCCCBIFDHBCBDCDDDGDIFGCCACCDABBCDAAAB@=>A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MPMLRQOQONDNNONNOPLPNOOLLNMMLBKMNLBBKNOOMLLCCLLLLLMMOOMMKDDMMLDENNMFFPPLDLL PG:Z:MarkDuplicates BI:Z:ORPNUSRSRPIPPQQQPRNRORRPOPOPOHOQQPHHNQSQPOOHHOPQPPQPSRRQPIIPQPIIPRQJJQSOHNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:C@BFFFFF XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CG MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2314:7160:72313#86 1107 11 22 60 75M * 22 -183 CAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAAT @<@A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:LKNNQQPNENNONOOPLOMOOLLMMMLCLNOLCCLNOPMLLDDLMMLLMMOONNKDDLNLEEMNLFFNPNHDLKK PG:Z:MarkDuplicates BI:Z:PNQPTTSRJQRRRRQSPSQSSPOQPPOHNQQPHHNQRQPOOHHOPPPOPPSRRQPIIPQPIIPQPIJQRQJHONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2205:6324:39178#86 83 11 22 60 75M * 22 -183 CAAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAAT B=?A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MLNNQRPODNOPNNOPLPNPPLLMMNLBKMNLBBKNOOMLLCCLLLLLMMOOMMKCCMMLDDMNMEEOOOGDMLL PG:Z:MarkDuplicates BI:Z:PNQPTTRQJPQRQQPRNRORRPOPOPOHOQQPHHNQRQQOOHHOPPPPPPSRRQPIIPQPIIPQPJJQRQKHONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:B@@FDFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2315:10776:22635#86 147 11 23 60 75M * 23 -190 AAGTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATA >AC>ABGCCDGCGGCGCHDGCDAIDIDDEGCCDDBCHEDHCBBECCBCIBIEHDCCACCBBADBBAACB@@>>?A X0:i:1 X1:i:0 MC:Z:75M BD:Z:LNNMRPODNOONNOPLOMOOLLMMMLAJLNLBBJNOOLKKBBKKKKKLLNNLLJBBKKJBBKKKCCLLLDEMMLL PG:Z:MarkDuplicates BI:Z:NQPPUSRJQRRRRPRNRORRPOOOONGNPPOGGMPQPONNGGNOOONONQPPOMGGNONGGNONGHOPOIIOPNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2211:4524:57005#86 147 11 25 60 75M * 25 -210 GTATCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAA B9=:/CFA=9B+:2C:DD:B6B@;=A76A@:7@?6@5<>; X0:i:1 X1:i:0 MC:Z:75M BD:Z:NMNMPFNOONNNOLOMNNKKLLLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKLJCCKLKDDMNKDKK PG:Z:MarkDuplicates BI:Z:PPQPSKRRSRRQRORPRRPOPOONGMPPOFFLOPONMMFFMNOOMNNQPPNNGFMOMGGNONGGNPOHHPQOHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2315:14995:18916#86 99 11 28 60 75M * 28 208 TCTTTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTT AAA8=GBCFBHDCG?DCBGF;GCAH=DDCB;A7CBA=A>( X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:LLMLGPOPPQQOLNMNOMLLLLKCLONLCCKMMOMLLBBLLLLLLLMOOOKBBLMLCCMMLCCNNMDEOPPCMPL PG:Z:MarkDuplicates BI:Z:NNPNKQRSSTRRORORSPPQOQOIQSQPHHOPQQPOPHHPPPOOPNQQRQNHHPPNHHPPNHHQQOJJRSRHORO AM:i:37 SM:i:37 MQ:i:60 QT:Z:@@@;=BDD XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2103:20842:81391#86 1171 11 31 60 75M * 31 -144 TTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCT >>D<=FBGAEDECCBHCEB?EG??C@@AE@E9@A@CCC@BE@FEBA@6>?CBBAD@BAAC?@:@BB=@DB@?1B@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:LMNMRQQNPNOOLLMMLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKLJCCKLJCCKLJDKNMMMMKK PG:Z:MarkDuplicates BI:Z:OPQQUSUQTQSSPOPPPOHNQPOGGMPQPNMMFFMNNNMNNPPPNMFGNOMGGMNNFGNONGGNOOHNQOPOONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2213:1473:19592#86 147 11 31 60 75M * 31 -144 TTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCT ?>D=DFBFBIBIDDBHCICCEGDCCCBCHEEHABBCACBCICIEGBBBBCCBBBDAABADABAACBAADD@??C@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:LMNMRQQNPNOOLLMMLKBKMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKLJCCKLJCCKLJDKNMMMMKK PG:Z:MarkDuplicates BI:Z:OPQQUSUQTQSSPOPPPOHNQPOGGMPQPNMMFFMNNNMNNPPPNMFGNOMGGMNNFGNONGGNOOHNQOPOONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2215:17245:37655#86 83 11 31 60 75M * 31 -166 TTCTAGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCT @>D>DFCHEHDGDBCICICDDICDDDACIEFHCACDADBCICIGGCBBBDABBBDBBBCDBBBBCBABEF@@>DA X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:LMNMRQRNQOPPMMNNMLCLNOLCCLNOPMLLDDLMMLLMMOONNKDDLMKDDLMKDDMNLEEMNMFMQOPMMKK PG:Z:MarkDuplicates BI:Z:OPQQUSURTRTSQPQQQPIORQPIHNQRQPOOHHOPPPOPPRQQPOHHOPPIIPQPIIPQPIIPQPJPSPQOONN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2209:8836:89456#86 147 11 35 60 75M * 35 -157 AGTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAA AB>DAGBHCBBIBFBDDHCBABBBHFEHABBDADCCFBHFGBAABDABBADABBBDCBABCAAAEGBCCEAB<=@ X0:i:1 X1:i:0 MC:Z:75M BD:Z:NNOLSPQQMMMMMLCLMNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKLJCCKLJCCKLJCJMKLMMQOLDKK PG:Z:MarkDuplicates BI:Z:QPROVSUTRPQQPOHNQQPHHMPQPONNGFMNNNMNNPOONMGGMNMGGNNNGFMOMGGNONGMPNOOORROHNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2315:14735:86781#86 147 11 36 29 64M11S * 36 -190 GTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCT B<@>A;HBB?HBE:?DCBBBC@AGDEEBABCBCBBHAHFEB@BBD@B@AAD@@BAA=A@@A?A?DA@@;C@ MC:Z:75M BD:Z:NOLOQRQNMNMMLCLNNKBBKMNOLKKCCKLLKKLLNNMMJCCKLJCCKLJCCKLJCCKLJCCKLJDKNMMMMKK PG:Z:MarkDuplicates BI:Z:PRORTUURQQQQOHNQQPHHNPQPONNGGMNNNMNNPOONMFGNNMFGNOMGGMNNFGNONGGNOOHNQOPOONN AM:i:29 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@STXY\Y[ZW_[Z]]a__a``\`__@@@@@@@@@@@ MD:Z:64 NM:i:0 RG:Z:rg HS29_09125:3:1116:2395:16071#86 147 11 36 29 64M11S * 36 -177 GTCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCT A?D>EBFCAC:CIBAEGC=ACBCGFDGABCC9CCCGCGGHCBADC?B@CB?ACCCBAB@CBABA>CA@DEA?=BA MC:Z:75M BD:Z:OPLPQRRNNONNMCLNNLBBKNOOMLKBBLLLLKMMONLLJBBKKJBBKKJBBKKJBBKKJBBLLKCKNLNMNLL PG:Z:MarkDuplicates BI:Z:PRNRSUURQRPQPHOQQPHHNQQQONNGGNOOONONQPPONGGNONGGNONGGMONGGNONGGNOOHNQPPOONN AM:i:29 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@TVW[[X[Z^]Z]__`a`a_ba`a`@@@@@@@@@@@ MD:Z:64 NM:i:0 RG:Z:rg HS23_09099:8:1204:9887:64457#86 83 11 37 29 39M5I31M * 37 -180 TCACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCTG >DBBBCBBBBDCBBBEABBBDBB?GGB@=ABA BC:Z:GTTGTCGG MC:Z:75M BD:Z:OLOMSRONOONMDMOPLCCLNOPMLLDDLMMLLMMOONNKDDLMKDDLMKDDLMKDDLNLEEMNLFMPOOQMPKK PG:Z:MarkDuplicates BI:Z:RORPVUSRRRRPIORRQIIORRQQOOHHOPPPOPPRQQPOHHOPOHHOPOIIPQPIIPQPIIPQPIPSPQQOQNN AM:i:29 SM:i:29 MQ:i:29 QT:Z:CCCFDDFF XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@]aaabaaaaa_^^]`\\[[\YXSX@@@@@@@ MD:Z:70 NM:i:5 RG:Z:rg HS29_09125:3:1209:13756:29838#86 147 11 39 60 75M * 39 -157 ACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAAT >C@CACCHCHBBFHCDCCCBHFDHCCDEBEDCIDGGGBACCDCDBCDBC@CCDCAADCBBEFCCDGDG@@DB=@A X0:i:1 X1:i:0 MC:Z:75M BD:Z:PNPPPOPOONCLNOMCBKNOOMLLCCKKKLLMMNOMMJBBKKJBBKKJBBKKJBBKKJBJLJKLMOMLDLNMMLL PG:Z:MarkDuplicates BI:Z:RORRTRSQRQIPRQPHHNQRQPNOGGNOOONONQPPONGGNONGGNONGGNONFGNONGMPNNNNQQOHOQOONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2102:8330:80497#86 147 11 39 60 75M * 39 -198 ACTCATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAAT >A?CAAAGBHCBFHCBCCCCHEDHCCCEBEDBIDGEGCCCCCCDACCBC@ACDCCCDCBBFFCCDGDG@@DA=@A X0:i:1 X1:i:0 MC:Z:75M BD:Z:PNPPPOPOONCLNOMCBKNOOMLLCCKKKLLMMNOMMJBBKKJBBKKJBBKKJBBKKJBJLJKLMOMLDLNMMLL PG:Z:MarkDuplicates BI:Z:RORRTRSQRQIPRQPHHNQRQPNOGGNOOONONQPPONGGNONGGNONGGNONFGNONGMPNNNNQQOHOQOONN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1209:5647:63540#86 83 11 42 60 75M * 42 -158 CATTCTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATC >==7ABHCBAACDBB@CFC?CA7B>@A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:OLLMQPOENPPMDDMOOPMLLDDLMMLLMMOONNKDDLMKDDLMKDDLMKDDLMKDKNMMNNQOMFMNOOQMNKK PG:Z:MarkDuplicates BI:Z:RPOPTSRKPSSQIIORSRQPPHHPPPPOPPRQQPOHHOPOHHOPOHHOPOIIPQPIOROPPPRRPIPQQQRPQNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:@@@DFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1304:13880:3781#86 1107 11 46 60 75M * 46 -164 CTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATA E>D?ACGCEADCCIEFHBBBCDCDDICIFHCBCADBABCBBBBBDBBBADBBBGHCDFJDEBBGGACAC@F?>?A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MMLCPQRNEEMOPQNMLDDLMMLLMMOONNKDDLMKDDLMKDDLMKDDLMKDKNLLMMQOMELMMNOOQRPLMKK PG:Z:MarkDuplicates BI:Z:PPOHRTTSJJPRSRQPPIIPQPPPPPRQQPOHHOPOHHOPOHHOPOHHOPPIOROPPPRRPIOPPPRRSTROPNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2204:11843:74480#86 83 11 46 60 75M * 46 -164 CTCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATA B>D?@DGCCCDCCGDDHBBBCDCDCEDIFHBBCADBABBC@CBBEBCBCDABBGHCDFJEHBBGGBCCCBD>>?A X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:MMLCPQRNEEMOPQNMLDDLMMLLMMOONNKDDLMKDDLMKDDLMKDDLMKDKNLLMMQOMELMMNOOQRPLMKK PG:Z:MarkDuplicates BI:Z:PPOHRTTSJJPRSRQPPIIPQPPPPPRQQPOHHOPOHHOPOHHOPOHHOPPIOROPPPRRPIOPPPRRSTROPNN AM:i:37 SM:i:37 MQ:i:60 QT:Z:CCCFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS29_09125:3:2104:4334:40723#86 147 11 47 60 75M * 47 -207 TCTTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATAT ?C?>AFCCADBBIEDHBBCCCECCIDIGFCCBCDBCBCCDCBBEBCBBECAAGHCCCHEGAAFGBDCCBF@@=?A X0:i:1 X1:i:0 MC:Z:75M BD:Z:NMCLQQODDMOPPNMMCCLLLLLMMONLLKCCLKKCCKKJBBKKJBBKKJBJLJKKLNLKBJKLLLLNPMNMMLL PG:Z:MarkDuplicates BI:Z:POHOUTSJJPRSRPOOHHOPPPNPNQPPONGGNONGGNONGGNONGGNONGMPMNNNPPNGMONNPPQRQPPPNN AM:i:37 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1109:11884:89828#86 99 11 49 29 27M5I43M * 49 263 TTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAA A>DICBDDBDCACBBBCCCEBCDCDADCDCDC?FC@HEFI:DCIBCC@>D?? BC:Z:GTTGTCGG MC:Z:75M BD:Z:KKDLSQOFFMOOPNNMDCLMMLLLLNPONLCCLMLCCLMLCCLMLCCLMLCCLMLCLOLMMMPPMENOOOQMONL PG:Z:MarkDuplicates BI:Z:NNHPTSQJJPQRRQPPIIQQQPPPOQQRQNHHPPNHHPPNHHPPNHHPPNHIPPOIPSPPPPRSQJQSRSTPQQN AM:i:29 SM:i:29 MQ:i:29 QT:Z:@@@DDDFF XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@cb`baaabb`a^__^_[]\\ZZWP@@@@@@@@@@@@@@@@@@@ MD:Z:70 NM:i:5 RG:Z:rg HS23_09099:8:1213:13470:6886#86 1171 11 49 29 27M5I43M * 49 -189 TTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAA ?>@CBBBAABHFEHABADBDBBICHFGBABAD@BBAFAABBCBABADCBBBDABBGHDBFIDGAAFGAB?@@@=@ MC:Z:75M BD:Z:CLNOPFENOPPMLLDDKLLKKLLNNMMJCCKLJCCKLJCCKLJCCKLJCCKLJCJMKKLLOMKCJKLLMNOOLKK PG:Z:MarkDuplicates BI:Z:HNQQTKKPSSRQOOHHOPPPOOOQPPONGFMNMFFMNMFFMNNGFMNNGGMONFLPLNNNPPNGMOOOPQRRPNN AM:i:29 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@_aa`e``aa`^]^\_^\[[\XXVX@@@@@@@@@@@@@@@@@@@ MD:Z:70 NM:i:5 RG:Z:rg HS23_09099:8:2315:16232:18677#86 147 11 49 29 27M5I43M * 49 -189 TTTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAA >>>CBBBAABIFFHBDAD@DCBIBHFGBABADABBAFAABBDAABADCBAADCBBGHDCFHDGAAFGAB?A?B>@ MC:Z:75M BD:Z:CLNOPFENOPPMLLDDKLLKKLLNNMMJCCKLJCCKLJCCKLJCCKLJCCKLJCJMKKLLOMKCJKLLMNOOLKK PG:Z:MarkDuplicates BI:Z:HNQQTKKPSSRQOOHHOPPPOOOQPPONGFMNMFFMNMFFMNNGFMNNGGMONFLPLNNNPPNGMOOOPQRRPNN AM:i:29 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@`aa`e``aaa]]^\_^\ZZ\ZXVX@@@@@@@@@@@@@@@@@@@ MD:Z:70 NM:i:5 RG:Z:rg HS23_09099:8:1102:19193:100659#86 83 11 50 29 26M5I44M * 50 -204 TTGATTTTACTGGAAAATATTCTCAGTAAAATAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAAT ?=C?@BCAEEEDHBBBD@DDCICIFHABBBDBCABDAA?ADCBBBD>BCBDA@AGGDDFHEHABEEAD@C@F?>>AHDEEABADAACBECIEG@ABADABBBC>AABCBABBDAABBDCABEHDBFIEGAAFGACBCCG?A=>?@ MC:Z:75M BD:Z:LCCLRRROMMDDLMMLKLLNNMMJCCKLJCCKLJCCKLJCCKLJCCKLJCJMKKLLOMKCJKKKLLNOLMNMLKK PG:Z:MarkDuplicates BI:Z:PHHNUUTRQPIIOPPPOPPRQPONGGNONFFMNMFFMNMFFMONFFMONGLPMMMNOPNGMNNNOPQRPPQPPNN AM:i:29 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@`aaab]``a`^]^]_\[[[\ZWVV@@@@@@@@@@@@@@@@@@@@@AE MD:Z:70 NM:i:5 RG:Z:rg HS23_09099:8:1205:12501:60669#86 99 11 65 60 75M * 65 221 AATATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATATTTTGACAAGGAAGGAGAA A@>>AAB@DDHA@CCB?>BB=>@CDCCBCC?C@BCBCBGFFCBADICDCC? X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:KKLMQOONNPQPOMDDMMLCCLMLCCLMLCCLMLCLOLLLLOOLCLMLLMMONLLMMLDEMPOLMNOOOOQMMML PG:Z:MarkDuplicates BI:Z:NNPPRQQQPRRSROIIQQOIIQQOIHPPNHHPPNHOROOOOQROHOPOPPPRQNQQQPIIQSQOPQQRRRSOPPO AM:i:37 SM:i:37 MQ:i:60 QT:Z:@=@BDFDA XT:A:U BQ:Z:DB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2209:19394:8174#86 99 11 68 60 75M * 68 177 ATTCTCAGTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATATTTTGACAAGGAAGGAGAAGAG AA@ X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:KKNLGFOONEDMNMDDMMLCCLMLCLOLLLLOOLCLMLLMMONLLMMLDDLONKLLMMLMNNNNMNOOPLQLCCL PG:Z:MarkDuplicates BI:Z:NNQNJJRRPIIQQOIIQQOIIQQOIOROOOOQROHOPOPPPQQNPPPOHHPSPNOPPPPPPPQQQQRSRMSOHHP AM:i:37 SM:i:37 MQ:i:60 QT:Z:CBBFFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:2301:4066:67915#86 1123 11 75 29 75M * 75 173 GTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATATTTTGACAAGGGAGGAGAAGAGGGAAAAT AA<@A@C5A@C95B?B?AA3=C<72188G8FE.;+H,+C7DEFADCA7A&@GFCI:D=+;12>>=>? X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:KKNLGFOONEDMNMDDMMLCCLMLCLOLLLLOOLCLMLLMMONLLMMLDDLONKLLMIMNNNNNMNOOPLQLCCL PG:Z:MarkDuplicates BI:Z:NNQNJJRRPIIQQOIIQQOIIQQOIOROOOOQROHOPOPPPQQNPPPOHHPSPNOPPKPQPPQQQQRSRMSOHHP AM:i:29 SM:i:29 MQ:i:29 QT:Z:?@7+4:8A XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A MD:Z:57A17 NM:i:1 RG:Z:rg HS23_09099:8:2303:2263:63446#86 1123 11 75 60 75M * 75 173 GTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATATTTTGACAAGGAAGGAGAAGAGGGAAAAT AA<@ABCCCDBDACC@ECDDDDADCFBBIFGICDCFDD=BCEFEDCDBCBJDGCCI>DCGDCIDDHEDEDA?@>? X0:i:1 X1:i:0 BC:Z:GTTGTCGG MC:Z:75M BD:Z:KKNLGFOONEDMNMDDMMLCCLMLCLOLLLLOOLCLMLLMMONLLMMLDDLONKLLMMLMNNNNMNOOPLQLCCL PG:Z:MarkDuplicates BI:Z:NNQNJJRRPIIQQOIIQQOIIQQOIOROOOOQROHOPOPPPQQNPPPOHHPSPNOPPPPPPPQQQQRSRMSOHHP AM:i:37 SM:i:37 MQ:i:60 QT:Z:CC@FFFFF XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A MD:Z:75 NM:i:0 RG:Z:rg HS23_09099:8:1116:11337:38257#86 83 11 75 60 75M * 75 -173 GTAAAATAAAATAAAATAAAATAAAGTTCCTGAAAGAATATCAATATTTTGACAAGGAAGGAGAAGAGGGAAAAT >=;?BFHBCEICB@BD>DCDBEHCIBGFHBGEHFGBFHEFEG?> ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 11 75 . G <*> 0 . DP=68;I16=6,62,0,0,2437,87909,0,0,3770,217210,0,0,838,15940,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 11 75 . GTAAAATAAAATAAAATAAAATAAA GTAAAATAAAATAAAATAAAATAAAATAAA 0 . INDEL;IDV=6;IMF=0.0882353;DP=68;I16=5,57,1,5,7440,892800,720,86400,3596,212164,174,5046,691,12331,147,3609;QS=0.834915,0.165085;VDB=0.00452698;SGB=-0.616816;RPBZ=-3.24592;MQBZ=-6.13241;MQSBZ=0;BQBZ=0;SCBZ=-0.546919;MQ0F=0 PL:AD 0,54,150:62,6 bcftools-1.21/test/mpileup/indel-AD.4.out000066400000000000000000000045241467060157400201710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 11 75 . G <*> 0 . DP=68;I16=6,62,0,0,2437,87909,0,0,3770,217210,0,0,838,15940,0,0;QS=1,0;MQ0F=0 PL:AD 0,205,255:68,0 11 75 . GTAAAATAAAATAAAATAAAATAAA GTAAAATAAAATAAAATAAAATAAAATAAA 0 . INDEL;IDV=6;IMF=0.0882353;DP=68;I16=5,57,1,5,7440,892800,720,86400,3596,212164,174,5046,691,12331,147,3609;QS=0.834915,0.165085;VDB=0.00452698;SGB=-0.616816;RPBZ=-3.24592;MQBZ=-6.13241;MQSBZ=0;BQBZ=0;SCBZ=-0.546919;MQ0F=0 PL:AD 0,54,150:62,6 bcftools-1.21/test/mpileup/mpileup-SCR.bam000066400000000000000000000045071467060157400205030ustar00rootroot00000000000000‹ÿBCpsrôete``pðpá ó³2Ô3át÷·ÊËÏKå ö·JÎÏ/JÉÌK,Iårä *àô¦\A.VEéœÁ¾Vʼn¹9©\Œ@ƒ˜€ØaJìà[‹ÿBC¹½˜Ë#WÆkfR"E¤£1™qÕ½·nÙ½‹ß/ 0¶«»mWÝz¸)ê F!ˆå±b3X^XH¬ÂšM{"…ÿE±b‡€Eá;·ìö«ËÝIzr]Õ¾¾UeYý;ß9ß¹ŸÞ1ôøNöht|Çxjx˜†ñ§¿üá¿b>LêåïWZj¹ÛêV«•z·Ói¶ºMŒº]i¿{Á0ÄÏÝ™r.Žù<ß—³þìøDäz‹Yž‰y.7œ»¹£g3M[šŽ¤Á¬RQri ^âSf9¬h;‘¶#EÑáŽÀ!h©Ä‹¼èX¼äH& ¦Ù\Lƒóé`:5Ôà¢ÕPFß½ð}¥â(Œ‚1†¯¼@)O© p*_ácàa·!Ö¼S¼cââJ*…?Aù4SFt~¡ž¼ý÷½·~úã§OÞýá;FtEq<‰&“ÈÇãpÅAŒ¥ Ž(Œã(š`?!Äm8F¸W†ñ$Nz8Á{ˆY*<ê%ïd§}gggÆ›OG¦Ó{ñÍw’?¾Ô/ßÞ0”‹ÿ”¨19¿xûGƧûø_8€¿Ý­VÊn»S©t;•f³úùñË¿u5~Iøå ?»Ä/KÜÖø…ãX¢`À­ð«,üÊ÷|*?ðOýmüŠ ¼ÿDãW—øC¯ñ„?þp?nÒø§Ñ!ü6ðÿúyãÿûþ÷µúi| çÏø›ÝJ­ õ·êín£Õn|Nõ ñÐ’;4€¶è”,§¢SæpV,r¬™S²%u`3)(lǶ%綰9{P0×ÈЂ= øàçÄ4$®¼äŠïøÀ×K.â$TxħÓFrp›N|!€ÆS?!ªÉDCá@‘þœnŠãÅFŒp¢K…¤±…˜¿+×*ï=GÌÿXb~Œ“kÌ\b~‹0謁R­€u³Ö©uë•F§±â|’BŽÃ>ùÞ\ å 3îæ|vt|Òë¹ ·×Ë3Óz Ž ¶ ÉÚæýo~£•ƒîRå|Wå|Så«$ïpY0 bKÚþj<2ûJÙŠ_¥l㳤}­²!é8 ' %öᦲ£TÙI„).îrþwÊù㟳œÿ³äÜ»ä¼]Ì?Òœk5pn5SÎå*q&=7ÛÍÖŠóMä<{Å*XÌÒ¥\r$sÇ–R /+ô ̶ãHDZKÀ Ì6dlÓRI”¬Ž©1YáUβÒ9 EÊC2÷|Àݵæ Ì@î§*ÆÌõô•¯oÒ§")@ÛaÉœQ~ˆÖÈu-v’9„¼‘Ì'IŒB,óÀ%s•@л%ýVÁ2>Øø üÇû.à«åV żY-×VàoÂýè1ΟmÛ2‹¦É M3¶oáä•Ž¥Ø¹Åa·`‡¡Ö”²«ÛÛS·¾#Ò´Ÿ•Èµº•‹mÔuû m ’X§þýDþ´^ÿþvëõÙçÏ–œ]âÌFÇ÷vnlsF¯”k]œ òkµ†Nä¿ÂMŸà‹Ü»È¢Ïs3!7˜Ïû=7æCq4\ÌŽfý³,“[Ž:m‘wl³¾8¶¬{ µ€Ò"¸cQ <¢cA` Ë›B×ÐÉp¥f¨\íš6OÈ1½èÎSÊ ¤îP)Ñ}Z¤¡‡{Ðiõ:I}´‚žÄã1ä>™&¤ümê =JIoufO¾4蛑~ÿ鉽ÞmÕZõn¥ƒÔN¤§wRÒsœÃ¡èÌ®Qü3fò‚m9VQ˜LUXtÛ!ÓêdÚ…¹cÚ…,ZRÀ tæœY…‡&£NÏLõ­Èû’ÿZr/ ¥km¯ ëuŸ&:›£¨§6}Ðx>Ð¥<“4D;’ #O´‰‹© $Äô‰Ê5µ^(რyõ@G€vë±.´J¤¿¾Azö­O^é3“úÃ~éU~zÙ†%[¤{{mXµßVm×ÊÝF½ziÛnR¼]fÁ‹ÉC ßlÀp`I8B ØvÄ Lg ªFM¸Ú¶)Ú{I’øF3j˜~ÝŒáJ0&ÿ˜A YÐcÄ É÷õ„ÊòV3Få›^ I{í5caìÓïÑ‘Ç;•|'©¿$¿ÚM˜áÎ_àüåÞ&L )½Ò®4ºj­}‰ÿÚÎŒçú¹W MßV\×oǶö÷^öº2i¾ëå¢-L;sf<†kBÝŠg{8O_Øöpc’?Ô ¾äü³4ykÖÙ{/ÈöÃTãË:tP´XÆL²‡ÿµ ü/§¦î#Â>tÝç…ÿ¯Küã óþ¯Ý®­Z­”¿Õiwëzy½ wü9˜÷WuC¾jÖÉLÆмAÛ6¹t(í›Í×Íš(9(ýˆŒ’Ð=xÛ´·ºótGÕ¿YƒF;2$wÏSc_7Üí½¢X«ÌN-^O´høH_ÝhЈ¸B ĺ6ÄÓ×ѺGû÷û·„÷q/s—M¾?:¾{­e«‘koÖQÉk­N³M€ŸáKê÷ ã°QÕ…Ì/ž™ìAD×/hÕPͯuhhÙÈØ£Ô[tµP(˜Ë½—@ëùj‡¦‹¹¦KLCÿÔ¥Žv\çÔ§•²Ï;ó˜îZ€ÁQÁ€”Aƒ&C„GƒÐT„e´È‹,ñÓsn§h ÐCS^ééžÁ-…rÕ±ÕúÇ…Þ%¬!ñгTÓEÚ¤W !õ0­sKçzD>$MõØN”ÌÁ fÒ*‹KnIn˜Ü°8¹aqrÃâ†ÉÁÉ ‹!1YõžJö! ‹c```ddbd``dfbˆŽS› ž± % ‹³±q10§ 'ph`'5‹ûÿÿÿþÿÿÿÿçg`øgc#¤‹+õ5¶»ž ‹cdd`FFFz¡ œîL‰0‹kXÞ°üÿÿÿß¹«ö7b``øÿÿÿƆކ7 <«¼ Ë<Ì‹c``+dƒ†nNph0I ‹c`fff&M5¦ 1— ‹ ŽŽŽŽÇM¾µ t•» ‹cä—`ä“`”–`” Œ0 Jtký ! ‹c``ddbdfaa``es‡æ eЄàBDZVƒé‹“ArA ÷ºï²ä*ÑÑÿ?“ÃÊ;±*y› &ðØÝ®µVa@E ‚Ø`Źc+7¤ZÝ)Àq&°?a¼‚‘ %æžï0«ý„YØgf0Õhk[/dH01oQÌ-Pf&‚KL’ãLpw³ÖÇÇË+?…‘[øIXg¢ÝÌZk2$“‹A&†É¥a˜Û€ä- ײ¤ƒ&õ8Û™µ0ÿ5ɽLÉq&ÕÝš–µ†?C¼Æ±5÷h‘”÷wªm'Ç™ÈnIÍÇGøÙ7!†hùʺß/Öî„ãLJ÷ÞXŸŽe-ô7/îó>&W¬oÔR‘ä8Yk¥e·|)Eki|] Iè.xUc­nvöµ÷ƒ’ïÞ/wuÛÍqæù(ù¿F dBfX!I…öÑàUZw?[Ž>a!ÓÜoª`¬Õý0÷ûqþA2›éÑ‹WàMQC ‹³±6øps¢ 1 ‘àASC ‹óöIIIoooq@‹)´ óCUíàXSC ‹“ ³“ív .b àmcIA,‹“Suä”Suä´Sqäü¬âÈi«êÈi´BžÉs…£éïà<œÿÿÿÿàEOF½ÙOîcKbcftools-1.21/test/mpileup/mpileup-SCR.fa000066400000000000000000000002601467060157400203220ustar00rootroot00000000000000>1 155264057-155264206 AAGTTGCAGCGCCCAATCATCATCTTCTGAGCCAGGAAAACCTTCTCTGCTGGGATCTCG ATGCCTAGGTCCCCCCGTGCCACCATGATGCCGTCGCTCACCTCCAGGATTTCATCAAAC CTGAGAGGTTGGGAGAATCAAGGCAGAGGC bcftools-1.21/test/mpileup/mpileup-SCR.fa.fai000066400000000000000000000000171467060157400210600ustar00rootroot000000000000001 150 23 60 61 bcftools-1.21/test/mpileup/mpileup-SCR.out000066400000000000000000000271341467060157400205540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 64 . C <*> 0 . DP=2;SCR=0;I16=1,1,0,0,65,2117,0,0,120,7200,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:SCR 0,6,65:0 1 65 . C <*> 0 . DP=3;SCR=0;I16=2,1,0,0,96,3080,0,0,180,10800,0,0,2,2,0,0;QS=1,0;MQ0F=0 PL:SCR 0,9,90:0 1 66 . T <*> 0 . DP=4;SCR=0;I16=3,1,0,0,120,3606,0,0,240,14400,0,0,5,9,0,0;QS=1,0;MQ0F=0 PL:SCR 0,12,106:0 1 67 . A <*> 0 . DP=4;SCR=0;I16=3,1,0,0,117,3431,0,0,240,14400,0,0,9,23,0,0;QS=1,0;MQ0F=0 PL:SCR 0,12,102:0 1 68 . G <*> 0 . DP=5;SCR=0;I16=4,1,0,0,164,5398,0,0,300,18000,0,0,13,45,0,0;QS=1,0;MQ0F=0 PL:SCR 0,15,133:0 1 69 . G <*> 0 . DP=8;SCR=3;I16=6,2,0,0,264,9048,0,0,396,21072,0,0,56,662,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,180:3 1 70 . T <*> 0 . DP=9;SCR=3;I16=6,3,0,0,275,8431,0,0,456,24672,0,0,64,782,0,0;QS=1,0;MQ0F=0 PL:SCR 0,27,193:3 1 71 . C <*> 0 . DP=9;SCR=3;I16=6,3,0,0,321,11473,0,0,456,24672,0,0,73,919,0,0;QS=1,0;MQ0F=0 PL:SCR 0,27,217:3 1 72 . C <*> 0 . DP=9;SCR=3;I16=6,3,0,0,318,11254,0,0,456,24672,0,0,82,1074,0,0;QS=1,0;MQ0F=0 PL:SCR 0,27,216:3 1 73 . C <*> 0 . DP=10;SCR=3;I16=7,3,0,0,348,12146,0,0,516,28272,0,0,91,1247,0,0;QS=1,0;MQ0F=0 PL:SCR 0,30,224:3 1 74 . C <*> 0 . DP=10;SCR=3;I16=7,3,0,0,350,12278,0,0,516,28272,0,0,100,1388,0,0;QS=1,0;MQ0F=0 PL:SCR 0,30,228:3 1 75 . C G,<*> 0 . DP=12;SCR=4;I16=6,2,3,1,274,9444,132,4392,480,28800,119,3601,55,501,54,1046;QS=0.697201,0.302799,0;VDB=0.0533436;SGB=-0.556411;RPBZ=1.63069;MQBZ=-3.26599;MQSBZ=0.111111;BQBZ=-0.515877;SCBZ=3.23349;MQ0F=0 PL:SCR 73,0,170,97,182,252:4 1 76 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,410,14076,0,0,599,32401,0,0,120,1726,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,233:4 1 77 . G <*> 0 . DP=12;SCR=4;I16=9,3,0,0,385,12495,0,0,599,32401,0,0,131,1927,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,225:4 1 78 . T <*> 0 . DP=12;SCR=4;I16=9,3,0,0,365,11201,0,0,599,32401,0,0,142,2150,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,213:4 1 79 . G <*> 0 . DP=12;SCR=4;I16=9,3,0,0,431,15825,0,0,599,32401,0,0,153,2395,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,247:4 1 80 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,416,14894,0,0,599,32401,0,0,164,2662,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,241:4 1 81 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,420,14802,0,0,599,32401,0,0,175,2951,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,243:4 1 82 . A <*> 0 . DP=12;SCR=4;I16=9,3,0,0,393,12893,0,0,599,32401,0,0,186,3262,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,232:4 1 83 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,438,15990,0,0,599,32401,0,0,197,3595,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,246:4 1 84 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,438,16014,0,0,599,32401,0,0,208,3950,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,247:4 1 85 . A <*> 0 . DP=12;SCR=4;I16=9,3,0,0,402,13470,0,0,599,32401,0,0,219,4327,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,230:4 1 86 . T <*> 0 . DP=12;SCR=4;I16=9,3,0,0,396,13074,0,0,599,32401,0,0,229,4675,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,225:4 1 87 . G <*> 0 . DP=12;SCR=4;I16=9,3,0,0,457,17411,0,0,599,32401,0,0,238,4992,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,255:4 1 88 . A <*> 0 . DP=12;SCR=4;I16=9,3,0,0,395,13003,0,0,599,32401,0,0,247,5327,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,224:4 1 89 . T <*> 0 . DP=12;SCR=4;I16=9,3,0,0,398,13204,0,0,599,32401,0,0,256,5680,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,226:4 1 90 . G <*> 0 . DP=12;SCR=4;I16=9,3,0,0,463,17867,0,0,599,32401,0,0,263,5949,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,255:4 1 91 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,451,16953,0,0,599,32401,0,0,269,6181,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,253:4 1 92 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,419,14667,0,0,599,32401,0,0,274,6374,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,240:4 1 93 . G <*> 0 . DP=12;SCR=4;I16=9,3,0,0,398,13262,0,0,599,32401,0,0,279,6577,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,228:4 1 94 . T <*> 0 . DP=12;SCR=4;I16=9,3,0,0,377,11857,0,0,599,32401,0,0,283,6739,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,217:4 1 95 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,419,14695,0,0,599,32401,0,0,287,6909,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,238:4 1 96 . G <*> 0 . DP=12;SCR=4;I16=9,3,0,0,402,13550,0,0,599,32401,0,0,290,7036,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,231:4 1 97 . C <*> 0 . DP=12;SCR=4;I16=9,3,0,0,454,17178,0,0,599,32401,0,0,293,7169,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,254:4 1 98 . T <*> 0 . DP=12;SCR=4;I16=9,3,0,0,420,14714,0,0,599,32401,0,0,295,7259,0,0;QS=1,0;MQ0F=0 PL:SCR 0,36,240:4 1 99 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,299,11183,0,0,480,28800,0,0,199,4951,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,211:0 1 100 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,267,8927,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,193:0 1 101 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,295,10879,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,208:0 1 102 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,293,10737,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,207:0 1 103 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,278,9676,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,201:0 1 104 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,296,10952,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,208:0 1 105 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,295,10891,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,209:0 1 106 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,276,9524,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,194:0 1 107 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,302,11410,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,219:0 1 108 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,295,10879,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,208:0 1 109 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,265,8779,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,185:0 1 110 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,268,8980,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,188:0 1 111 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,266,8846,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,186:0 1 112 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,263,8647,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,184:0 1 113 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,300,11256,0,0,480,28800,0,0,200,5000,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,212:0 1 114 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,272,9252,0,0,480,28800,0,0,198,4902,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,198:0 1 115 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,265,8779,0,0,480,28800,0,0,195,4759,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,185:0 1 116 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,299,11179,0,0,480,28800,0,0,191,4573,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,211:0 1 117 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,271,9187,0,0,480,28800,0,0,187,4395,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,197:0 1 118 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,271,9187,0,0,480,28800,0,0,182,4176,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,197:0 1 119 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,267,8935,0,0,480,28800,0,0,177,3967,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,193:0 1 120 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,295,10879,0,0,480,28800,0,0,171,3719,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,210:0 1 121 . C <*> 0 . DP=8;SCR=0;I16=6,2,0,0,293,10735,0,0,480,28800,0,0,165,3483,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,207:0 1 122 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,282,9946,0,0,480,28800,0,0,159,3259,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,205:0 1 123 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,308,11864,0,0,480,28800,0,0,152,2998,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,223:0 1 124 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,269,9049,0,0,480,28800,0,0,145,2751,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,189:0 1 125 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,303,11483,0,0,480,28800,0,0,137,2469,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,220:0 1 126 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,266,8854,0,0,480,28800,0,0,129,2203,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,188:0 1 127 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,289,10547,0,0,480,28800,0,0,121,1953,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,210:0 1 128 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,295,10879,0,0,480,28800,0,0,113,1719,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,210:0 1 129 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,252,7952,0,0,480,28800,0,0,105,1501,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,178:0 1 130 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,264,8714,0,0,480,28800,0,0,97,1299,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,185:0 1 131 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,299,11199,0,0,480,28800,0,0,89,1113,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,215:0 1 132 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,292,10666,0,0,480,28800,0,0,81,943,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,212:0 1 133 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,292,10662,0,0,480,28800,0,0,73,789,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,208:0 1 134 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,266,8850,0,0,480,28800,0,0,65,651,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,187:0 1 135 . G <*> 0 . DP=8;SCR=0;I16=6,2,0,0,292,10698,0,0,480,28800,0,0,57,529,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,211:0 1 136 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,249,7793,0,0,480,28800,0,0,49,423,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,178:0 1 137 . A <*> 0 . DP=8;SCR=0;I16=6,2,0,0,252,7976,0,0,480,28800,0,0,41,333,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,181:0 1 138 . T <*> 0 . DP=8;SCR=0;I16=6,2,0,0,245,7547,0,0,480,28800,0,0,33,259,0,0;QS=1,0;MQ0F=0 PL:SCR 0,24,174:0 1 139 . C <*> 0 . DP=6;SCR=0;I16=5,1,0,0,212,7516,0,0,360,21600,0,0,27,199,0,0;QS=1,0;MQ0F=0 PL:SCR 0,18,159:0 1 140 . A <*> 0 . DP=5;SCR=0;I16=4,1,0,0,162,5266,0,0,300,18000,0,0,22,150,0,0;QS=1,0;MQ0F=0 PL:SCR 0,15,132:0 1 141 . A <*> 0 . DP=4;SCR=0;I16=3,1,0,0,132,4370,0,0,240,14400,0,0,18,110,0,0;QS=1,0;MQ0F=0 PL:SCR 0,12,116:0 1 142 . G <*> 0 . DP=4;SCR=0;I16=3,1,0,0,142,5090,0,0,240,14400,0,0,14,78,0,0;QS=1,0;MQ0F=0 PL:SCR 0,12,125:0 1 143 . G <*> 0 . DP=3;SCR=0;I16=2,1,0,0,105,3683,0,0,180,10800,0,0,11,53,0,0;QS=1,0;MQ0F=0 PL:SCR 0,9,99:0 1 144 . C <*> 0 . DP=3;SCR=0;I16=2,1,0,0,102,3486,0,0,180,10800,0,0,8,34,0,0;QS=1,0;MQ0F=0 PL:SCR 0,9,96:0 1 145 . A <*> 0 . DP=2;SCR=0;I16=2,0,0,0,63,1989,0,0,120,7200,0,0,6,20,0,0;QS=1,0;MQ0F=0 PL:SCR 0,6,58:0 1 146 . G <*> 0 . DP=2;SCR=0;I16=2,0,0,0,70,2450,0,0,120,7200,0,0,4,10,0,0;QS=1,0;MQ0F=0 PL:SCR 0,6,64:0 1 147 . A <*> 0 . DP=2;SCR=0;I16=2,0,0,0,60,1800,0,0,120,7200,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:SCR 0,6,55:0 1 148 . G <*> 0 . DP=1;SCR=0;I16=1,0,0,0,35,1225,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:SCR 0,3,35:0 1 149 . G <*> 0 . DP=1;SCR=0;I16=1,0,0,0,34,1156,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:SCR 0,3,34:0 bcftools-1.21/test/mpileup/mpileup-filter.1.out000066400000000000000000000036471467060157400215540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 100 . A <*> 0 . DP=1;I16=1,0,0,0,34,1156,0,0,0,0,0,0,25,625,0,0;QS=1,0;MQ0F=1 PL 0,3,4 bcftools-1.21/test/mpileup/mpileup-filter.2.out000066400000000000000000000036541467060157400215530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 100 . A <*> 0 . 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C <*> 0 . DP=18;I16=16,1,0,0,672,27586,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL 0,27,189 0,9,118 0,15,134 17 101 . C <*> 0 . DP=18;I16=16,1,0,0,630,24730,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL 0,27,182 0,9,108 0,15,132 17 102 . C <*> 0 . DP=18;I16=16,1,0,0,676,27812,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL 0,27,188 0,9,121 0,15,139 17 103 . T C,<*> 0 . DP=18;I16=15,1,1,0,668,28542,6,36,929,54841,29,841,323,7035,6,36;QS=2.98256,0.0174419,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64924;SCBZ=4;MQ0F=0 PL 0,17,184,24,187,185 0,9,118,9,118,118 0,15,147,15,147,147 17 104 . G C,<*> 0 . DP=18;I16=15,1,1,0,601,24163,3,9,929,54841,29,841,320,6884,7,49;QS=2.98726,0.0127389,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64309;SCBZ=4;MQ0F=0 PL 0,18,173,24,176,173 0,9,101,9,101,101 0,15,133,15,133,133 17 105 . G <*> 0 . DP=19;I16=17,1,0,0,603,22351,0,0,1018,59282,0,0,325,6815,0,0;QS=3,0;MQ0F=0 PL 0,30,171 0,9,106 0,15,125 17 106 . G <*> 0 . DP=19;I16=17,1,0,0,636,25058,0,0,1018,59282,0,0,324,6718,0,0;QS=3,0;MQ0F=0 PL 0,30,190 0,9,92 0,15,124 17 107 . C <*> 0 . DP=19;I16=17,1,0,0,686,27952,0,0,1018,59282,0,0,323,6643,0,0;QS=3,0;MQ0F=0 PL 0,30,192 0,9,119 0,15,136 17 108 . C <*> 0 . DP=19;I16=17,1,0,0,681,27429,0,0,1018,59282,0,0,322,6590,0,0;QS=3,0;MQ0F=0 PL 0,30,190 0,9,119 0,15,135 17 109 . T C,<*> 0 . DP=19;I16=16,1,1,0,716,30648,2,4,989,58441,29,841,309,6415,12,144;QS=2.98922,0.0107817,0;SGB=-0.556633;RPBZ=-0.674966;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.6661;SCBZ=3;MQ0F=0 PL 0,20,191,27,194,191 0,9,120,9,120,120 0,15,150,15,150,150 17 110 . G <*> 0 . DP=19;I16=17,1,0,0,688,28036,0,0,1018,59282,0,0,320,6550,0,0;QS=3,0;MQ0F=0 PL 0,30,194 0,9,113 0,15,136 17 111 . G <*> 0 . DP=19;I16=17,1,0,0,573,21453,0,0,1018,59282,0,0,318,6514,0,0;QS=3,0;MQ0F=0 PL 0,30,167 0,9,95 0,15,119 17 112 . C G,<*> 0 . DP=19;I16=16,1,1,0,657,26565,2,4,989,58441,29,841,301,6277,15,225;QS=2.98907,0.010929,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65292;SCBZ=3;MQ0F=0 PL 0,20,187,27,190,187 0,9,103,9,103,103 0,15,135,15,135,135 17 113 . A G,<*> 0 . DP=19;I16=16,1,1,0,635,25055,4,16,989,58441,29,841,297,6207,16,256;QS=2.98817,0.0118343,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65205;SCBZ=3;MQ0F=0 PL 0,20,172,27,175,172 0,9,102,9,102,102 0,15,139,15,139,139 17 114 . C <*> 0 . DP=19;I16=17,1,0,0,660,25876,0,0,1018,59282,0,0,310,6446,0,0;QS=3,0;MQ0F=0 PL 0,30,181 0,9,113 0,15,133 17 115 . C A,<*> 0 . DP=21;I16=17,2,1,0,688,27426,12,144,1078,62882,29,841,283,5827,25,625;QS=2.88785,0.11215,0;SGB=-0.556633;RPBZ=0.260329;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.47798;SCBZ=-0.418446;MQ0F=0 PL 0,30,189,30,189,189 3,0,86,9,89,93 0,21,153,21,153,153 17 116 . A C,<*> 0 . DP=21;I16=17,2,1,0,705,27791,2,4,1078,62882,29,841,287,6073,19,361;QS=2.98873,0.0112676,0;SGB=-0.556633;RPBZ=0.0867763;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.65814;SCBZ=2.65016;MQ0F=0 PL 0,20,179,27,182,179 0,9,102,9,102,102 0,21,175,21,175,175 17 117 . G <*> 0 . DP=21;I16=18,2,0,0,715,28045,0,0,1107,63723,0,0,304,6444,0,0;QS=3,0;MQ0F=0 PL 0,30,185 0,9,97 0,21,177 17 118 . G <*> 0 . DP=20;I16=17,2,0,0,620,23470,0,0,1047,60123,0,0,303,6481,0,0;QS=3,0;MQ0F=0 PL 0,27,175 0,9,65 0,21,162 17 119 . G <*> 0 . DP=19;I16=16,2,0,0,619,23459,0,0,987,56523,0,0,301,6493,0,0;QS=3,0;MQ0F=0 PL 0,27,176 0,6,76 0,21,160 17 120 . A G,<*> 0 . DP=19;I16=15,2,1,0,646,25392,4,16,958,55682,29,841,277,5999,23,529;QS=2.9873,0.0126984,0;SGB=-0.556633;RPBZ=0.28942;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.6486;SCBZ=3;MQ0F=0 PL 0,18,171,24,174,171 0,6,88,6,88,88 0,21,171,21,171,171 17 121 . G <*> 0 . DP=19;I16=16,2,0,0,650,25148,0,0,987,56523,0,0,298,6534,0,0;QS=3,0;MQ0F=0 PL 0,27,181 0,6,84 0,21,168 17 122 . C <*> 0 . DP=20;I16=17,2,0,0,696,27784,0,0,1047,60123,0,0,296,6560,0,0;QS=3,0;MQ0F=0 PL 0,27,180 0,9,107 0,21,178 17 123 . T <*> 0 . DP=18;I16=15,2,0,0,647,26145,0,0,927,52923,0,0,296,6554,0,0;QS=3,0;MQ0F=0 PL 0,24,170 0,9,123 0,18,166 17 124 . T <*> 0 . DP=19;I16=16,2,0,0,606,22002,0,0,987,56523,0,0,296,6564,0,0;QS=3,0;MQ0F=0 PL 0,27,154 0,9,114 0,18,154 17 125 . A T,<*> 0 . DP=18;I16=14,2,1,0,589,22565,4,16,898,52082,29,841,272,5916,25,625;QS=2.98444,0.0155642,0;SGB=-0.556633;RPBZ=1.02125;MQBZ=-2.16025;MQSBZ=-1.23956;BQBZ=-1.64106;SCBZ=2.91548;MQ0F=0 PL 0,15,149,21,152,149 0,9,114,9,114,114 0,18,162,18,162,162 17 126 . A <*> 0 . DP=18;I16=15,2,0,0,629,24725,0,0,927,52923,0,0,298,6536,0,0;QS=3,0;MQ0F=0 PL 0,24,162 0,9,117 0,18,174 17 127 . C <*> 0 . DP=18;I16=15,2,0,0,627,24331,0,0,927,52923,0,0,299,6549,0,0;QS=3,0;MQ0F=0 PL 0,24,163 0,9,119 0,18,160 17 128 . A <*> 0 . DP=18;I16=15,2,0,0,660,26364,0,0,927,52923,0,0,300,6580,0,0;QS=3,0;MQ0F=0 PL 0,24,169 0,9,121 0,18,168 17 129 . A <*> 0 . DP=17;I16=14,2,0,0,627,25407,0,0,867,49323,0,0,302,6628,0,0;QS=3,0;MQ0F=0 PL 0,24,168 0,9,124 0,15,159 17 130 . A <*> 0 . DP=17;I16=14,2,0,0,627,25419,0,0,867,49323,0,0,304,6692,0,0;QS=3,0;MQ0F=0 PL 0,24,169 0,9,124 0,15,152 17 131 . C <*> 0 . DP=16;I16=13,2,0,0,593,24003,0,0,838,48482,0,0,280,6096,0,0;QS=3,0;MQ0F=0 PL 0,21,167 0,9,120 0,15,147 17 132 . A <*> 0 . DP=16;I16=13,2,0,0,610,25250,0,0,838,48482,0,0,281,6139,0,0;QS=3,0;MQ0F=0 PL 0,21,169 0,9,120 0,15,151 17 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQ0F=0 PL 0,21,163 0,9,105 0,15,150 17 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQ0F=0 PL 0,21,177 0,9,105 0,15,152 17 135 . T <*> 0 . DP=15;I16=13,2,0,0,605,24553,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQ0F=0 PL 0,21,173 0,9,106 0,15,159 17 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQ0F=0 PL 0,21,172 0,9,105 0,15,134 17 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQ0F=0 PL 0,21,160 0,9,104 0,15,139 17 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQ0F=0 PL 0,21,172 0,9,108 0,15,142 17 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQ0F=0 PL 0,21,161 0,9,106 0,15,143 17 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQ0F=0 PL 0,21,163 0,9,107 0,15,153 17 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQ0F=0 PL 0,18,158 0,9,108 0,15,142 17 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQ0F=0 PL 0,18,157 0,9,97 0,15,129 17 143 . G <*> 0 . DP=14;I16=12,2,0,0,426,13778,0,0,778,44882,0,0,292,6648,0,0;QS=3,0;MQ0F=0 PL 0,18,128 0,9,95 0,15,102 17 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQ0F=0 PL 0,18,152 0,9,105 0,15,129 17 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQ0F=0 PL 0,18,153 0,9,106 0,15,138 17 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQ0F=0 PL 0,18,152 0,9,103 0,15,128 17 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQ0F=0 PL 0,18,150 0,9,99 0,15,140 17 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQ0F=0 PL 0,18,157 0,9,106 0,15,146 17 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQ0F=0 PL 0,18,148 0,9,109 0,15,140 17 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQ0F=0 PL 0,18,153 0,6,84 0,15,152 bcftools-1.21/test/mpileup/mpileup.1.sam000066400000000000000000012551631467060157400202450ustar00rootroot00000000000000@HD VN:1.0 SO:coordinate @SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human @RG ID:ERR013140 LB:g1k-sc-HG00100-A SM:HG00100 PI:450 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR016352 LB:g1k-sc-HG00100-A SM:HG00100 PI:450 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR156632 LB:3815246 SM:HG00100 PI:352 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR162872 LB:3815246 SM:HG00100 PI:349 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR162875 LB:3815246 SM:HG00100 PI:348 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242939 LB:6503965 SM:HG00100 PI:459 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242943 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242947 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242951 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242955 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242959 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242963 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242967 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242971 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242975 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242979 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242983 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242987 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242991 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242995 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR242999 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243003 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243007 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243011 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243015 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243019 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243023 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243027 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243031 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243035 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243039 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243043 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243047 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243051 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243055 LB:6503965 SM:HG00100 PI:455 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243059 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243063 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243067 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243071 LB:6503965 SM:HG00100 PI:455 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243075 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243079 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243083 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243087 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR243091 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245024 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245028 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245032 LB:6503965 SM:HG00100 PI:459 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245034 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245038 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245041 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245045 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245049 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 @RG ID:ERR245053 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 @PG ID:bwa_index PN:bwa VN:0.5.9-r16 CL:bwa index -a bwtsw $reference_fasta @PG ID:bwa_aln_fastq PN:bwa PP:bwa_index VN:0.5.9-r16 CL:bwa aln -q 15 -f $sai_file $reference_fasta $fastq_file @PG ID:bwa_sam PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1350 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.1 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1056 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.2 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1047 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.3 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1044 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.4 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1377 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.5 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.6 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.7 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.8 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.9 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.10 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.11 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.12 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.13 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.14 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.15 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.16 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.17 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.18 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.19 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.20 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.21 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.22 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.23 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.24 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.25 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.26 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.27 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1365 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.28 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.29 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1365 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.30 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.31 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.32 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.33 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.34 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.35 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.36 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1377 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.37 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:bwa_sam.38 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:sam_to_fixed_bam PN:samtools PP:bwa_sam VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.1 PN:samtools PP:bwa_sam.1 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.2 PN:samtools PP:bwa_sam.2 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.3 PN:samtools PP:bwa_sam.3 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.4 PN:samtools PP:bwa_sam.4 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.5 PN:samtools PP:bwa_sam.5 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.6 PN:samtools PP:bwa_sam.6 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.7 PN:samtools PP:bwa_sam.7 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.8 PN:samtools PP:bwa_sam.8 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.9 PN:samtools PP:bwa_sam.9 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.10 PN:samtools PP:bwa_sam.10 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.11 PN:samtools PP:bwa_sam.11 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.12 PN:samtools PP:bwa_sam.12 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.13 PN:samtools PP:bwa_sam.13 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.14 PN:samtools PP:bwa_sam.14 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.15 PN:samtools PP:bwa_sam.15 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.16 PN:samtools PP:bwa_sam.16 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.17 PN:samtools PP:bwa_sam.17 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.18 PN:samtools PP:bwa_sam.18 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.19 PN:samtools PP:bwa_sam.19 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.20 PN:samtools PP:bwa_sam.20 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.21 PN:samtools PP:bwa_sam.21 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.22 PN:samtools PP:bwa_sam.22 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.23 PN:samtools PP:bwa_sam.23 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.24 PN:samtools PP:bwa_sam.24 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.25 PN:samtools PP:bwa_sam.25 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.26 PN:samtools PP:bwa_sam.26 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.27 PN:samtools PP:bwa_sam.27 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.28 PN:samtools PP:bwa_sam.28 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.29 PN:samtools PP:bwa_sam.29 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.30 PN:samtools PP:bwa_sam.30 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.31 PN:samtools PP:bwa_sam.31 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.32 PN:samtools PP:bwa_sam.32 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.33 PN:samtools PP:bwa_sam.33 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.34 PN:samtools PP:bwa_sam.34 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.35 PN:samtools PP:bwa_sam.35 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.36 PN:samtools PP:bwa_sam.36 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.37 PN:samtools PP:bwa_sam.37 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:sam_to_fixed_bam.38 PN:samtools PP:bwa_sam.38 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:gatk_target_interval_creator PN:GenomeAnalysisTK PP:sam_to_fixed_bam VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.1 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.2 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.3 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.4 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.5 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.6 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.7 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.8 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.9 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.10 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.11 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.12 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.13 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.14 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.15 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.16 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.17 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.18 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.19 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.20 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.21 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.22 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.23 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.24 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.25 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.26 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.27 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.28 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.29 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.30 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.31 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.32 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.33 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.34 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.35 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.36 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.37 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:gatk_target_interval_creator.38 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:bam_realignment_around_known_indels PN:GenomeAnalysisTK PP:gatk_target_interval_creator VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.1 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.2 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.3 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.4 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.5 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.6 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.7 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.8 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.9 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.10 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.11 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.12 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.13 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.14 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.15 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.16 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.17 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.18 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.19 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.20 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.21 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.22 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.23 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.24 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.25 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.26 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.27 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.28 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.29 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.30 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.31 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.32 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.33 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.34 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.35 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.36 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.37 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_realignment_around_known_indels.38 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_count_covariates PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.1 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.2 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.3 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.4 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.5 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.6 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.7 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.8 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.9 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.10 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.11 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.12 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.13 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.14 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.15 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.16 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.17 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.18 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.19 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.20 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.21 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.22 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.23 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.24 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.25 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.26 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.27 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.28 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.29 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.30 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.31 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.32 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.33 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.34 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.35 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.36 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.37 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_count_covariates.38 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_recalibrate_quality_scores PN:GenomeAnalysisTK PP:bam_count_covariates VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.1 PN:GenomeAnalysisTK PP:bam_count_covariates.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.2 PN:GenomeAnalysisTK PP:bam_count_covariates.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.3 PN:GenomeAnalysisTK PP:bam_count_covariates.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.4 PN:GenomeAnalysisTK PP:bam_count_covariates.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.5 PN:GenomeAnalysisTK PP:bam_count_covariates.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.6 PN:GenomeAnalysisTK PP:bam_count_covariates.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.7 PN:GenomeAnalysisTK PP:bam_count_covariates.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.8 PN:GenomeAnalysisTK PP:bam_count_covariates.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.9 PN:GenomeAnalysisTK PP:bam_count_covariates.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.10 PN:GenomeAnalysisTK PP:bam_count_covariates.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.11 PN:GenomeAnalysisTK PP:bam_count_covariates.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.12 PN:GenomeAnalysisTK PP:bam_count_covariates.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.13 PN:GenomeAnalysisTK PP:bam_count_covariates.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.14 PN:GenomeAnalysisTK PP:bam_count_covariates.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.15 PN:GenomeAnalysisTK PP:bam_count_covariates.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.16 PN:GenomeAnalysisTK PP:bam_count_covariates.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.17 PN:GenomeAnalysisTK PP:bam_count_covariates.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.18 PN:GenomeAnalysisTK PP:bam_count_covariates.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.19 PN:GenomeAnalysisTK PP:bam_count_covariates.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.20 PN:GenomeAnalysisTK PP:bam_count_covariates.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.21 PN:GenomeAnalysisTK PP:bam_count_covariates.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.22 PN:GenomeAnalysisTK PP:bam_count_covariates.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.23 PN:GenomeAnalysisTK PP:bam_count_covariates.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.24 PN:GenomeAnalysisTK PP:bam_count_covariates.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.25 PN:GenomeAnalysisTK PP:bam_count_covariates.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.26 PN:GenomeAnalysisTK PP:bam_count_covariates.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.27 PN:GenomeAnalysisTK PP:bam_count_covariates.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.28 PN:GenomeAnalysisTK PP:bam_count_covariates.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.29 PN:GenomeAnalysisTK PP:bam_count_covariates.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.30 PN:GenomeAnalysisTK PP:bam_count_covariates.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.31 PN:GenomeAnalysisTK PP:bam_count_covariates.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.32 PN:GenomeAnalysisTK PP:bam_count_covariates.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.33 PN:GenomeAnalysisTK PP:bam_count_covariates.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.34 PN:GenomeAnalysisTK PP:bam_count_covariates.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.35 PN:GenomeAnalysisTK PP:bam_count_covariates.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.36 PN:GenomeAnalysisTK PP:bam_count_covariates.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.37 PN:GenomeAnalysisTK PP:bam_count_covariates.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_recalibrate_quality_scores.38 PN:GenomeAnalysisTK PP:bam_count_covariates.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_calculate_bq PN:samtools PP:bam_recalibrate_quality_scores VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.1 PN:samtools PP:bam_recalibrate_quality_scores.1 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.2 PN:samtools PP:bam_recalibrate_quality_scores.2 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.3 PN:samtools PP:bam_recalibrate_quality_scores.3 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.4 PN:samtools PP:bam_recalibrate_quality_scores.4 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.5 PN:samtools PP:bam_recalibrate_quality_scores.5 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.6 PN:samtools PP:bam_recalibrate_quality_scores.6 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.7 PN:samtools PP:bam_recalibrate_quality_scores.7 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.8 PN:samtools PP:bam_recalibrate_quality_scores.8 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.9 PN:samtools PP:bam_recalibrate_quality_scores.9 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.10 PN:samtools PP:bam_recalibrate_quality_scores.10 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.11 PN:samtools PP:bam_recalibrate_quality_scores.11 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.12 PN:samtools PP:bam_recalibrate_quality_scores.12 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.13 PN:samtools PP:bam_recalibrate_quality_scores.13 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.14 PN:samtools PP:bam_recalibrate_quality_scores.14 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.15 PN:samtools PP:bam_recalibrate_quality_scores.15 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.16 PN:samtools PP:bam_recalibrate_quality_scores.16 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.17 PN:samtools PP:bam_recalibrate_quality_scores.17 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.18 PN:samtools PP:bam_recalibrate_quality_scores.18 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.19 PN:samtools PP:bam_recalibrate_quality_scores.19 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.20 PN:samtools PP:bam_recalibrate_quality_scores.20 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.21 PN:samtools PP:bam_recalibrate_quality_scores.21 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.22 PN:samtools PP:bam_recalibrate_quality_scores.22 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.23 PN:samtools PP:bam_recalibrate_quality_scores.23 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.24 PN:samtools PP:bam_recalibrate_quality_scores.24 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.25 PN:samtools PP:bam_recalibrate_quality_scores.25 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.26 PN:samtools PP:bam_recalibrate_quality_scores.26 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.27 PN:samtools PP:bam_recalibrate_quality_scores.27 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.28 PN:samtools PP:bam_recalibrate_quality_scores.28 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.29 PN:samtools PP:bam_recalibrate_quality_scores.29 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.30 PN:samtools PP:bam_recalibrate_quality_scores.30 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.31 PN:samtools PP:bam_recalibrate_quality_scores.31 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.32 PN:samtools PP:bam_recalibrate_quality_scores.32 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.33 PN:samtools PP:bam_recalibrate_quality_scores.33 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.34 PN:samtools PP:bam_recalibrate_quality_scores.34 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.35 PN:samtools PP:bam_recalibrate_quality_scores.35 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.36 PN:samtools PP:bam_recalibrate_quality_scores.36 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.37 PN:samtools PP:bam_recalibrate_quality_scores.37 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_calculate_bq.38 PN:samtools PP:bam_recalibrate_quality_scores.38 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_merge PN:picard PP:bam_calculate_bq VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.1 PN:picard PP:bam_calculate_bq.1 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.2 PN:picard PP:bam_calculate_bq.2 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.3 PN:picard PP:bam_calculate_bq.3 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.4 PN:picard PP:bam_calculate_bq.4 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.5 PN:picard PP:bam_calculate_bq.5 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.6 PN:picard PP:bam_calculate_bq.6 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.7 PN:picard PP:bam_calculate_bq.7 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.8 PN:picard PP:bam_calculate_bq.8 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.9 PN:picard PP:bam_calculate_bq.9 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.10 PN:picard PP:bam_calculate_bq.10 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.11 PN:picard PP:bam_calculate_bq.11 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.12 PN:picard PP:bam_calculate_bq.12 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.13 PN:picard PP:bam_calculate_bq.13 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.14 PN:picard PP:bam_calculate_bq.14 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.15 PN:picard PP:bam_calculate_bq.15 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.16 PN:picard PP:bam_calculate_bq.16 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.17 PN:picard PP:bam_calculate_bq.17 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.18 PN:picard PP:bam_calculate_bq.18 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.19 PN:picard PP:bam_calculate_bq.19 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.20 PN:picard PP:bam_calculate_bq.20 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.21 PN:picard PP:bam_calculate_bq.21 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.22 PN:picard PP:bam_calculate_bq.22 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.23 PN:picard PP:bam_calculate_bq.23 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.24 PN:picard PP:bam_calculate_bq.24 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.25 PN:picard PP:bam_calculate_bq.25 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.26 PN:picard PP:bam_calculate_bq.26 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.27 PN:picard PP:bam_calculate_bq.27 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.28 PN:picard PP:bam_calculate_bq.28 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.29 PN:picard PP:bam_calculate_bq.29 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.30 PN:picard PP:bam_calculate_bq.30 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.31 PN:picard PP:bam_calculate_bq.31 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.32 PN:picard PP:bam_calculate_bq.32 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.33 PN:picard PP:bam_calculate_bq.33 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.34 PN:picard PP:bam_calculate_bq.34 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.35 PN:picard PP:bam_calculate_bq.35 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.36 PN:picard PP:bam_calculate_bq.36 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.37 PN:picard PP:bam_calculate_bq.37 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.38 PN:picard PP:bam_calculate_bq.38 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates PN:picard PP:bam_merge VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.1 PN:picard PP:bam_merge.1 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.2 PN:picard PP:bam_merge.2 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.3 PN:picard PP:bam_merge.3 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.4 PN:picard PP:bam_merge.4 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.5 PN:picard PP:bam_merge.5 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.6 PN:picard PP:bam_merge.6 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.7 PN:picard PP:bam_merge.7 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.8 PN:picard PP:bam_merge.8 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.9 PN:picard PP:bam_merge.9 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.10 PN:picard PP:bam_merge.10 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.11 PN:picard PP:bam_merge.11 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.12 PN:picard PP:bam_merge.12 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.13 PN:picard PP:bam_merge.13 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.14 PN:picard PP:bam_merge.14 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.15 PN:picard PP:bam_merge.15 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.16 PN:picard PP:bam_merge.16 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.17 PN:picard PP:bam_merge.17 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.18 PN:picard PP:bam_merge.18 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.19 PN:picard PP:bam_merge.19 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.20 PN:picard PP:bam_merge.20 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.21 PN:picard PP:bam_merge.21 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.22 PN:picard PP:bam_merge.22 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.23 PN:picard PP:bam_merge.23 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.24 PN:picard PP:bam_merge.24 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.25 PN:picard PP:bam_merge.25 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.26 PN:picard PP:bam_merge.26 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.27 PN:picard PP:bam_merge.27 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.28 PN:picard PP:bam_merge.28 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.29 PN:picard PP:bam_merge.29 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.30 PN:picard PP:bam_merge.30 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.31 PN:picard PP:bam_merge.31 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.32 PN:picard PP:bam_merge.32 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.33 PN:picard PP:bam_merge.33 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.34 PN:picard PP:bam_merge.34 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.35 PN:picard PP:bam_merge.35 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.36 PN:picard PP:bam_merge.36 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.37 PN:picard PP:bam_merge.37 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates.38 PN:picard PP:bam_merge.38 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.39 PN:picard PP:bam_mark_duplicates VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.1.39 PN:picard PP:bam_mark_duplicates.1 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.2.39 PN:picard PP:bam_mark_duplicates.2 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.3.39 PN:picard PP:bam_mark_duplicates.3 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.4.39 PN:picard PP:bam_mark_duplicates.4 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.5.39 PN:picard PP:bam_mark_duplicates.5 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.6.39 PN:picard PP:bam_mark_duplicates.6 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.7.39 PN:picard PP:bam_mark_duplicates.7 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.8.39 PN:picard PP:bam_mark_duplicates.8 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.9.39 PN:picard PP:bam_mark_duplicates.9 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.10.39 PN:picard PP:bam_mark_duplicates.10 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.11.39 PN:picard PP:bam_mark_duplicates.11 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.12.39 PN:picard PP:bam_mark_duplicates.12 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.13.39 PN:picard PP:bam_mark_duplicates.13 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.14.39 PN:picard PP:bam_mark_duplicates.14 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.15.39 PN:picard PP:bam_mark_duplicates.15 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.16.39 PN:picard PP:bam_mark_duplicates.16 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.17.39 PN:picard PP:bam_mark_duplicates.17 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.18.39 PN:picard PP:bam_mark_duplicates.18 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.19.39 PN:picard PP:bam_mark_duplicates.19 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.20.39 PN:picard PP:bam_mark_duplicates.20 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.21.39 PN:picard PP:bam_mark_duplicates.21 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.22.39 PN:picard PP:bam_mark_duplicates.22 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.23.39 PN:picard PP:bam_mark_duplicates.23 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.24.39 PN:picard PP:bam_mark_duplicates.24 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.25.39 PN:picard PP:bam_mark_duplicates.25 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.26.39 PN:picard PP:bam_mark_duplicates.26 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.27.39 PN:picard PP:bam_mark_duplicates.27 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.28.39 PN:picard PP:bam_mark_duplicates.28 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.29.39 PN:picard PP:bam_mark_duplicates.29 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.30.39 PN:picard PP:bam_mark_duplicates.30 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.31.39 PN:picard PP:bam_mark_duplicates.31 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.32.39 PN:picard PP:bam_mark_duplicates.32 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.33.39 PN:picard PP:bam_mark_duplicates.33 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.34.39 PN:picard PP:bam_mark_duplicates.34 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.35.39 PN:picard PP:bam_mark_duplicates.35 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.36.39 PN:picard PP:bam_mark_duplicates.36 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.37.39 PN:picard PP:bam_mark_duplicates.37 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.38.39 PN:picard PP:bam_mark_duplicates.38 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT ERR013140.3521432 99 17 1 29 22S86M = 226 313 AGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCA @AEDGBHIIIIIFJGIKHGHIJJJEJKHJKJKGKLLIFHKLLCJJIDEFFHKHEHHJIIIDJEEEJEIKGJIHCGKHFKFE9BBDIAJAHF4?DE@I:DD48(86D=> MD:Z:86 RG:Z:ERR013140 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@iidijgijijfjkkhegjkkbiihcdeegjgdggihhhcidddidhjfihgbfjgejedXaach`i`geS^cd_hYccSWGWUc\] ERR156632.12704932 163 17 1 29 36S64M = 195 293 TGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTG BFAFGFEIGFEFHHEIDKJGHHHJIIE=@KKGGKJGIBLLMFKMDIIHJKKHFELLLKFIHMHIHHIHLKJFCHFJIJAID=JHKFGHJIHKKCH:@HD? MD:Z:64 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@hakklejlchhgijjgedkkkjehglghgghgkjiebgeihi`hc\igjefgihgjjbgY_gc^ ERR156632.9601178 99 17 1 29 62S38M = 279 377 CTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGA DEEEIIHHKIJILKHLHIKEKHHMKLKKJGKKKKLKLFIHEKIKL=KLJLKIILHKMH9LJJJJLHLHJJKJJKMLKJD>MJKLEHIGHIH=FFCHF>BE MD:Z:38 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@iikgkgiijiijlkjic]lijkdghfghg\eebge]ad ERR162872.21706338 99 17 1 29 10S90M = 246 344 CTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCA BHBFHDKHGHJFJIFIDFDIJHHJHHIICKKKIJIHH?JJKEKGHGJCGGEHFIHJHFK;HGIHIJGICIEDH X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243011 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J ERR162875.9416595 163 17 23 60 100M = 239 314 ATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGC DBDIGHGHIBKJIIKIJJGJGKKIKILIKKLJLLKKJJILIJJLMKKIJJHIKLLKJKHDELMJHFKIKDKDKIHHILFKLHBMKGLJ7KGDJHBBFFGD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.23732910 163 17 25 60 100M = 299 373 AGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTT DFEEGGHGJDIHKJIIHHHLKKLHIILLKKMILLKHKMIMMLJLLKLIGJFIKMJJKEMMLHKGDIJ?CILGIIJJLKLL6KMKLM7IIGJGJF?CFEG? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@ ERR162872.5127873 113 17 28 37 100M * 0 0 TAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAAC .BDEFHG?AEFGHIFCEHLGIIFJIA@LCFKAFJDJDEIBHELKIJMH8FJJKHAMG>GHGKHAKFKHHGGEL=LIJJIILCJHJGHJIHEFIFI9DBGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.19056012 113 17 32 37 100M * 0 0 TGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAAC DFGEGFDK;HFFHJJDJHFJJKILKDMIJFDKJMIMJKM@HAMIL=KKMHHLHM8GKKECMHJLHGM=BLMJIKKJLHJJKGHKIJJ@IHJFEEGHDBGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.19886608 177 17 33 37 108M * 0 0 GCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCA %CCD@ACF?E@DBECDF@FHGFEDHEHGABBCC>@FFD>FCGKEELCIHLGKJJGCHHJDBCIIJJIFIJJGDGHCCGGEFFCAEGD: X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243079.1328786 177 17 33 37 100M * 0 0 GCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACA DEDDICIGFGFIJHGFJGG?KGJCHKCHFICIKEHGFHGJDJ@ICIFEAGKBKC@CHFBKFBHFEGEDEJHHHIFJEGHHEDGHDHJHHJFCDDGCADE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243027.254838 177 17 36 37 100M * 0 0 TGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCT ?B.F)9:GCFJ=CGBD0DFG0AL5;;CHIH?8/F?C65G=E0=BBFD>BD? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.3774900 177 17 48 37 108M * 0 0 TTTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATC 4&4%4-<'CH>+GD8<6<<;85562@>C:>310155<+/4568-&,)8*7=6,9;D261>CG@6?@>/H=8@HB:FEFED@<>DB?-2?@=>BA9 X0:i:1 X1:i:0 MD:Z:1G106 RG:Z:ERR016352 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.8688512 113 17 48 37 100M * 0 0 TGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATA DCF.AGFCKCGDBJILEK@CEKGHL9:B7GM<3F<:BH=FC0KC;HM:K;DKGCHLM?IG>@GMJFECHHGCDIIBEFI:GAHBCBDCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243063.860385 113 17 58 37 100M * 0 0 GAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCC AA@@FADGFKI?HCHFE@IFI:?GGJHFIIJIEBHFFKGFHIIHJ@HJHCLGIKGDHJHHIIJJIGFGEIGBGIGHJGGEGHJH@IEHEFGIFHIEBB>A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR162872.19371403 99 17 64 60 100M = 413 448 GCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAG BDGFHHEEGFIIHKJIIJDJKKHIKKIJEIIJIIIKLKLMKKILLLKJKIJLJMLLIMKKEHEGJFJKGKLLMJKJIMLCJIHFKJKIJEDKEGIEHD?F X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR162872.10929052 163 17 69 60 100M = 429 459 GGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAG E>EFFIJJKKIIJIHKKIJNLIIDKIHEKJLLMLLLKKJKJLJKGJNJIJKKMLIIIKGIKKKKHMKLHMKILLAJJJIKLJLLGILLJKJFDHDEGFD1 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:F@CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.10099033 163 17 87 60 100M = 384 396 CCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACG D?DEGBHHIIIJKGHKKIGJKLJIBLJIGIFGJHGLEECAJIJCFJIKLGHI@KCFEJCJJJ3IJLGJKJLLIHHEGGJD?H4EHIADJE>D>7FCF@8* X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.753594 99 17 95 60 100M = 555 559 CAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTC ?ECDFG9FGH8EIGFHAIEHFHJFGG@JF?DGGEDEGGEKHIAJGFJI@GGFEGIEHEFHJHGEDHHHE@>@EK>HFHC@JFFDI3CEHHGAGEEECF@B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR013140.20277196 163 17 97 29 34M74S = 339 349 ACTCCCCCGGCCCGGGGCCCGGGGGCTTTACAAAAAACTGTCCAGCGCATACCCGCATCCCCCCAAAAGAAGCCACCGCCCCAACACACACCCCCCACCCGCATAACC 824475'$-2)*#(/#%(/#(/-%-%-/%0/88800($,+3(*+..,%%+6%*#%2,/001)%%$2%%/$.%$00(,%+,1'*.%7(%&$&#'$$$#%#%#($+%+)" XC:i:35 MD:Z:6T0G4T2C0A2A3A4A5 RG:Z:ERR013140 AM:i:29 NM:i:8 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.19887184 113 17 99 37 40S68M * 0 0 GTGTGTGTCGGGGGTGTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGA %$($&$*+#%%#1'$$%2-'0&3*/$/$-73/69:7=1%2135??3C<6;:9@<46@G@EBB=FEBF<@95 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.4461044 113 17 114 37 17S91M * 0 0 ACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATCCCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACC /=1:/=44-348<0(910@955>D;??@=>>=<@DE?IIIHFJFJHGIHGHECCB@ X0:i:1 X1:i:0 XC:i:91 MD:Z:33A57 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245034.1618692 163 17 124 60 100M = 510 485 TAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAG >ABDECDGFEHGHFHFFJF@GGGDGHHGJGFJHHHDKH@I@JGEGHGGJHBGHGHGCLGIHH@IGIFGKGHIAJIHHGEGHHIJFHIHHHEIECFCFBCE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245034 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR245038.421367 177 17 131 37 100M * 0 0 CATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGC A>7EBHBFIGE>JEJFC/KFCKGEHGKFIJ@IEHD=JJJJCGACHEJGEHDFFFBGFFJHEGFIIKILHFFHHKGKJGFHHJEFJEHIGGEIGIIEE?C@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR156632.396790 177 17 133 37 100M * 0 0 TCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCC >FDAGAHKICK>IBHJMJD?IFKILGEKAEJKLE:LKLGGCL1@KHGHKDMGCIKII@DH:KKHGLFIGCFLIJIHHGKJGJJHHHHJEIHGIFB@FA@B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR243011.687269 177 17 133 37 100M * 0 0 TCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCC ,G0I=C718G?2IB91/1FACI1?319I=IHADEF@DI5GBH5DJFHF=7;9G@G2DB5F?K2C;F.7G>7GCF9H=B<'GF?:BA1* X0:i:1 X1:i:0 MD:Z:71G28 RG:Z:ERR242939 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243083.1184095 177 17 168 37 100M * 0 0 GCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGT CFG1F@CBDD>9HICI:@F=HIHIGDHPJBDFFG@IFEHKBDIJICJIELH?DEFHEHCGA8:@GBIJELIJ@HLE:LHKHEL:FDLKHE8IJGHJHDDLJLJIKFJLLLLJIHLGMHJJLLKJBJ8MIK>GLKK6HLKHJG7IEHIG@FCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.15310883 163 17 201 60 100M = 519 417 AACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACA BCDFGHGFFGIIJGKHFKGKIILIJIIKCHLHJIILIJIJENHMGHLGJKILLKHIHHLKJMKKJHIHLKLJKJMJHBFJMFLLKJIIKAHHFFGGFFDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245053.675620 163 17 213 60 90M1I9M = 408 294 TAGAAGTGAAGGCACCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGAC ?AHDDHEHEGJEIGGH@HHHGHGIFHGHBIIIHGHEIHHJJHGFFFGJLJGIEIFEKFJKHIHGKHEHHG=JJJGGJKFEJBHFJGGFICEHGCGGE=C8 X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR245053 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.3521432 147 17 226 29 19S89M = 1 -313 CACCCCTAGAAGTGACGGCCCCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTGCCTGCGACAAA 71%??A9A792/7-2%(&:$::+BC@<=E>=EFCFHILHEDJNKHLFJFGGIMGGMMGKBKFMLELFMJJDEEJFJLIJIHIJFJHIHIFHEHIEGHJIFBGEJEFJIJGIDCFHICEEGDCA? X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR242975 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242943.1259162 163 17 236 60 67M1I32M = 565 428 GACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAA ED?HCII?>H76E;=CDG=FJHDEDIAE?AB9@ X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR242943 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@G ERR245049.65948 113 17 237 37 66M1I33M * 0 0 ACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAA ?F@>HAHHFDBGGIGAIDCGFHJFKBDHHIHAMKGEGGDHIEEEHGJHJJHEHHGFJEJFHAGHJ@HIJJFIAJEJEEGJHHIEFGHHDFEIFCEBBA@? X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR245049 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DFFG ERR162875.9416595 83 17 239 60 64M1I35M = 23 -314 ACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAAC 0?FGAHFHI?IKEHLFCK?DLH/?EBLIJEHKIMFKJLLHDFLJGJGLGHLFGKCHLILHIHJGHKBKJJCKGHHGGKJHJDEHIKGGGIFDEEDDCCFB X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.21706338 147 17 246 29 100M = 1 -344 TGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCT BB7EHGIKJJIJGFIIKFMKGIKKIILJBLKLEJ9IMMKKKJFLJGKKIHDLGMLHIMKMILEJILDGLLMKHIIKMMIJHLIDHJH>GHHKHIJFGEEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243047.1018873 99 17 254 60 49M1I50M = 653 498 TTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA @=CDDGGGI@HGJEEIJGIIJGEJFHHKIKHJJGGKBDEGDJEHGIFHEFKGHIHKCGCDFFFLJGGHHIKGF@HEGFBEDFHC=DJFCEHFFHECBC:/ X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR243047 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243055.2002258 1187 17 254 29 49M1I50M = 653 496 TTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA A>A?DDH:HD>CGDBCE>65H9BGIK>JKFH<92.>J.;95FE3353+8839?/4H/.9CAE/ X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR243055 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245032.1218650 163 17 255 60 48M1I51M = 543 387 TATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAG ?ACAFFGGFFFJDFJHHJIJIHKGGHKHHIJHHHJ7FFHGHFJHIGLEDIJIIIKBGIHGHIIJLGIFLJJEDKH@FBDHHHHJIJIHEKGHHIEACICE X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR245032 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR243071.874302 177 17 262 37 100M * 0 0 CCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAA @EEIGGEEIEIGCJGJFEIFJIICKHGLG?GJ3JEIFEGDCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@I@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.6409758 163 17 293 60 100M = 651 457 GACACACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCAT ECFGFHHHKFJJKLKJBIIKJCHKILFM>HHNKJF??IIHKHHLJNIEHHJJMFJILBIHHIEHIHMJJLJHEMCJIJJHLLIGJKLJLHHHJFKIIJILIHIHLJFHEKIHH?JGGGHIFEGCBCCA X0:i:1 X1:i:0 MD:Z:0C0A0G0T52G43 RG:Z:ERR162875 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:d^de@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR162875.15521446 83 17 314 60 100M = 41 -372 AGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCA EEEEGEFHLKHCJLDIDHHBIGHMJDMIGJLIJJJAELMLKKLMMKIGHGFKHHJGMJLHIKJIJLLDIHHLHIIGLIIIHEHGGGFEGGGFHIHDDEGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.24509474 99 17 325 60 100M = 581 355 ATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATA BDEEFDEEFGGFHKKJKGKKKKIGHHKJMJLBKJLJJHJHKHIJIKMLJJIMIIHJKIHHIMHIJMJIGJGHBHJHIJFLIKHJLFDKIJKIIFCCDBEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR162875.16695705 163 17 332 60 100M = 647 414 AAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGG 79@(D+JGDCD7@KI&%=/HGC/BBA9<7>JH:1HI9=FFJI:;0,6H5D)A6IHH29EBAAB@DC( X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.20277196 83 17 339 29 108M = 97 -349 CCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCA 4AB@(8G1B?AFFFHJ>HGJJHH@HJHIGIHNIHHHLHKLHJKJIIJLKKGJHIHKKJIIIIHKKHKKIIKKLIGKKJIGHHHGHHGHHHJJFIIGFIFFGIHFFDA@ X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.8214205 99 17 346 60 108M = 676 437 GGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAA @BCCFGIGIGHHIHJIJJGHKGHGJKJKGHIHHIJLIHHGLIIIJLHIHIIIIKFKIIIIJLHLIIKKHIKKKHILKHHJHHGKLMJHGGHEGDIGIHFEHCHDDFCB X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HHH ERR243007.996298 1187 17 357 60 100M = 683 425 CAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATG BDGEEFFFIFGEHKIKFHEKHEJIIAFFJIHDJIGFDHAFFEHHIIHJHJHHJDFIFFJIHHHFHHEEGJEJHIHGGDEHFFHHKHIKHHHIFIEGE?DD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243027.1412318 163 17 357 60 100M = 683 425 CAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATG ADGEFFGFJHHEGJIIHGEJFEIIJEFDIIEGIIIGEGEFEEJHGHFJFJFHHFEKHHIFJHGGEJGDIIFHIMHGGFEGIFHHKIHMJGJFFGDFDEBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.23475567 163 17 362 60 100M = 503 240 AATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGT B?DHGBAHGGDGCHGFEIIEIEIFLGH=7G:DACIIJJ>AJGBBAAD5JA8E=F(CEBDFBB>CEDGDGEC1CDB=DAFCFEFHJACEFFF>@ACCACG=BCDBBBC@9 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.11659627 163 17 375 60 108M = 645 360 AGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTTATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGA :FD@CDEABEEHCCHIHGGGDDDGJJJHEIGIJGJEE/HIJMKJIIKKIILIIHKKMGFEJJFIHKMLLMLKHHINKLLLIHKJGKGJFFAJCH1GFBFBHGD>BDB; X0:i:1 X1:i:0 MD:Z:37C70 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.7259970 163 17 378 60 108M = 660 377 TGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAG :DEE??CCGBCGHGGFGDDDGJJJHEIHIJGJEEIIIJLKJIHKKIIKIIHKKMDGFIJFJIJMKJMLJHJJMKHJLJHKKGJGIIIGJGDDGF>JFDHE?BCECEEE X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ABE ERR162875.10099033 83 17 384 60 100M = 87 -396 ACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAG 6BD0@6?BH;6BCHFE>6JJHHAEMJBALKIM18KBCHJB?IFIMJLBDKIHBFDGGEFJIIDIJHKFHAIJKKBHFJJGCHHFF>HGCDEEGED>DFGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR156632.5355545 99 17 398 60 100M = 640 341 AAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGAC C@C=FFJGGHHKGGLGHIJKJIHDJIIHIJJLNLHHHDFHIJDMFJLGMILHKGJKHILIJGJHLFJJJIJHLGIMMIHGGHLIKKHNJMIGFHIGEFBA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.15901000 83 17 399 60 100M = 175 -323 AAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACA CBD7GGIKHKHH@KJJLJHJHFHJHHKJHMKLKJHJHIJIMLMHKLLLNGJKJIHJJKLIHKJLKHMGIILIIIIKLIIIKHJJJJJJHFEGFGDHFFGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:HGF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245053.675620 83 17 408 60 100M = 213 -294 CTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCAC FCEDHFEGGJGEEGEGFIFBKHFJIIGICEDJKKFHKKGLBJKGFDGEJKGHHGIKEHFEFGH:HIHKEGEIJKJJJJIJFEHGJGHIFIGEFGGECGCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245053 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.15069550 99 17 412 60 100M = 742 429 CATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAA AEEGDEFFAFCEEDH5HGHHDG>HIG7IJBCDBC?HI>F<@GJFAED@MGJILIHHII?JKHKHJGGGFGEJFGGGIGDEFGHB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.7627281 99 17 434 60 100M = 618 283 TATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTC BCCDDEFIGGJIGIJHIFIIBGKGIGKILIIHIGJJMHIKIKIHHIMGJLJKCMGDIJLIIMIKGKIJJIMBIKJIJIHIIJILKKHK@IDGIGIGH?=D X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.15927236 99 17 441 60 108M = 653 319 GAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAA @CEDGIEJFGIIIIFHIJGHHHIKGGGGJIHHIJJLHHHIJKJLJLJLJKIJLKJLHLIIIJJKJLHKHKIHGJEGJJGFJLIEIKKFFJFGFIGC;HHEHACF@BB= X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@AC@ ERR162872.257723 163 17 452 60 100M = 628 275 AAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTG DAEFIIFGKHKIIJJIEGMJILKKIFIHNCJLHMJMHHJILJILJJHIEJKHMKJJILJIEEEEKLFIFKJGIMKJLLLIIKLJJKDFLEIJHC>FEEC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:IFG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242971.1689116 163 17 452 60 99M1S = 861 508 AAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCAGTGCAGCTTTCTACCATCACCAAAACTTC :>9A>6CGE::3ADE?G>ECBHGA12.AKC;I;?C>;D6;+F8JFBH.C<=2F@H.AF)G7H@,*9I;$9000F>9;3;4)D@E8(?8?:EDD?;B*C%/ X0:i:1 X1:i:0 XC:i:99 MD:Z:71T24A2 RG:Z:ERR242971 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@PNLT@W@@ ERR156632.4899095 99 17 457 60 100M = 835 477 CATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAAC DEDGFJIHHGIIILEGJJJJHHHLKILHLGLGIJHHJILJJJGJJKHLJKKIJJKIHJKMMMHILJIELLIOLLFIKLFJLGHLJJKJHJFGFDIHFCD= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242943.1830749 163 17 457 60 100M = 890 532 CATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAAC ABCBGIFCFFFHHJEDIGGBFDELIBF>J0IGGHGJFI==GCCABKBKHIGHLG?H?BH@HJ;?JGH;IIGLJIGDJI>HFIAEHEGEFEFGF>EFCDC< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.29762488 163 17 466 60 108M = 716 350 AAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAA 9@>:?A=BAA??7@AGBABCCBD?H@?EA@B;EDADEEABEFG:GAB>>::?>><@@HDDCIEGD:A)BD<>C< X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242979.1294369 163 17 468 60 100M = 781 412 AAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCC ?AGDCGFGEDCBIGFIFJGJEHCGIGCHFFDEADIEGHHGFJHGGGGGJJHFFJGGAJHHKJJEGKCBGIHHKGHJFBIEEEFGJGHFIFFHFCFE6EG9GGICC@;HHILIHIICFEKJ<9JI9I<3J7I=EKBDF?A2FHIK2BFFJJD(J5E@F697?@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AE ERR243011.373069 83 17 483 60 100M = 18 -564 GAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAAC <8BFHA>DFDHIC:H;D?BHHGDAH:JAH>FDHHEHHFJGHIIIAJJGFGMCB;JFGI2HHFFFAECG9H9ECIEEEHEJBAIEGJDEIDEIFFCBEAB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243011 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@BB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.18011293 163 17 488 60 100M = 748 359 AAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATC EAEFIHHKHIIHIIKHKLJJKJJJIJJKHLLHILJIIMLIMKMGILNJJKJJMIKMIHKIHJILLJKGJJJJKJJJIEKLLMHLGAJKLEJEHHHHGFDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.8507187 99 17 498 60 100M = 764 365 ATATGTCCACACAAATACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGCAGTCATCAACAACAAGC B>8C1E0+B,;BG5<-+);K0EI@AI,(HEI2C2+J+F<)9KL1DDHG-=#2F1G)E:9HA?DICAGDE)B X0:i:1 X1:i:0 MD:Z:15A66A1C13A1 RG:Z:ERR162872 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.23475567 83 17 503 60 100M = 362 -240 TCCACACAACATCCTGTTCATTGCAGCTTTCTGCCATCACCAAAAAGTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTG C.=7?7F7C.A1<83K9D299HH?@CM12C=B6>DDEECA X0:i:1 X1:i:0 MD:Z:9A1A20A13T53 RG:Z:ERR162875 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR162875.21460873 99 17 505 60 100M = 796 390 CACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGACCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGT 5E;:AD>BEF-7IJEF;6HBE3,IJGAG/J7I)GDKHF7B2;J;H2DICH1BBE(?>*4BB*@>L2>HG,,G*2:/87+8@21''.FDJ/AH;=*-C+6B*B70=IFD=D>E759'85?5<) X0:i:1 X1:i:0 MD:Z:99A0 RG:Z:ERR245028 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245045.954816 163 17 517 60 100M = 913 495 TGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAA >FDAFFCCGHGJGJEFIHEHHHGIFGIEHHHFGCILHHGJGGHIEGIDAHHIIEJFGGIKIJIFEHGFFGKGGEHIHH?FKHDEFHIFGCDGEHFFEEEC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245045 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR162872.2317332 163 17 518 60 100M = 701 282 GTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAAT DDCDGGGJJILJKHHJLGIKHJKJILKJJJJJGILJJJJIGJKJHJHDLKLJHLJCJKKIIKFKJLJHHKKJGJIGIHIKLHLFJJIHEDGBJGHFEFBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245038.1576181 99 17 519 60 100M = 949 529 TTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATG ?@ECECHHFJHHFEIHDIHFFJGIGGGGGGGFGHGHGHEHJJGGFIAIHFKFLHHJIJCHFG7IJKGGJGGIHIHHH@EGDKEGG;ADFHEGDEEEDDCF X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR156632.15310883 83 17 519 60 100M = 201 -417 TTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATG BGFEFHHIJKMAJJLJIJLIJIGJLGHHIIHJLJDHILHHKJHMGEILJMKIKFHMJ=LLLGFLJMIIHHHKHHLHHHIJJHJJJJGHGIIJGIFIEDCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR245032.1218650 83 17 543 60 100M = 255 -387 CAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGG EDBCBEFFKKFGFIFEGJEJFBLIILGIHDEJHIIHJFGLGJHIJGFLGFJEFFLFIKHEHIGFFGIKEJEJEHGGIEIKDGJFLIEIJIDFIDDEDFBA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.753594 147 17 555 60 100M = 95 -559 ACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTG BE;A?IEHEAIIILADGFGAHGFIKFEIIIHHLFFJFDHEDDKGEIHIDHHEHIIHEIEIGGCHIFHI?EIGLHEJIJEFJFCEFIIJEHIECEIFEGC@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR242939.81544 147 17 565 60 100M = 152 -512 GCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCTCTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAA +./6&=F=9A-0H1)GD:@:C(AD-ID=?/>7C)>0@B@(I7/HGH?46GBE8G9C-DBIGC<@IFDE49DG.B;BJC??JEDHCCF=FDDDG9E3AIAD4IEG;FDCCDAEEEH?? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.26172147 147 17 569 60 100M = 478 -190 TTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGA (7=C87CDG?6BAFIH8JDGBLHJBHA;JE@2>;I/AI=0=LEMEMI;KDD7;E3'=I;?B<7GHI7HEE7L4K65GHGJH/BLFDJHHIIIHJDC;EF2H+8@IHIE@%/FEKGLFI8@?CHA6JIH?IBAFF@MF20L4IDBGHBDJIIJJB%)%>G@#/IGGJIHJL?8GJAGK6GJJJJG;HHEAHGCBD X0:i:1 X1:i:0 MD:Z:15A28A16A4C0A32 RG:Z:ERR156632 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR162872.24509474 147 17 581 60 100M = 325 -355 ACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTC DGFGCGJGHMHHKHHHMJKKEKJDJIDJKNJLIKIIKLLIKMGLMJMAJMKLHJLKGJHMKMILLHIIMJKNILJJIKJKLLHIKJLHKKKHHJFFFHCE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245024.739014 163 17 584 29 20M1D80M = 935 450 CATCAACAACAAACTTGTGGTTACCCACACAATGGAAAACCACCTAGCAAAAAAAAGGACCCAAATCCTGGTACATGCAACTGACAGATGAATCTCAAAC ?CCEEDGGGHFG2>H/C6J8EE<:HH080=2G03I.G,,;E0()I(0&:H,,IJDJ0J.-H)G@*./I0>I;D6;/0*/G8;09+.<-./7I9...8DD9 MD:Z:20^T17G5T6C10A2C35 RG:Z:ERR245024 AM:i:29 NM:i:6 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@I@d_@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242959.1635151 99 17 588 60 100M = 998 509 AACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCGGGTACATGCAACTGACAGATGAATCTCAAACGCT @?EBE@G?DHCBA>E:;FBFGD=@ECHEE=@6:72GIGEIIA;EJE8FHH5F6K6:AHGA??EK5(:D0BCEFG2IIHI9?G7E5GHAAAA8EFC3><1( X0:i:1 X1:i:0 MD:Z:65T33A0 RG:Z:ERR242959 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.14628028 163 17 612 60 108M = 865 360 CACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGG ;D@DDACFDGGHCFGDIEFHGHFDHIFIJIJEEHGJJCHEHJIHBHDGHII8HFIGI9J@IFIGKFFBHAJJF>GIAE8IF=B:EE@G4F@@9:EAH@C;BF?3C<9320E-DGDJ*>EA@DF8369I1:D>D/-6F,H;H0EC?,AJG?.I)=/I%=FE/C*%%1<06F)#GECD:,< X0:i:1 X1:i:0 MD:Z:26C28T15T12A1A13 RG:Z:ERR243015 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.7627281 147 17 618 60 100M = 434 -283 GGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACA HKBLLHIHFEGJFIGHHHCIKFIDJKIIDIIGIMDHKJGDAKBLGHLJKHJEHJIJ@GHFGGJFFGIFGEGFCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR013140.11659627 83 17 645 60 17S91M = 375 -360 TTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGA %5?-$)89<=;9>(.144==2@>BD@>DBCDFIGFFIIEBF@HDFFFFCABDC@BC;CFFLCJGEJF15E*?:E2JCB(I/2)80DBH*G;K)**)-L0HCC?IGHBGFDLCEDDFBE8@KBC?FEC9?FECFFHFH>HAFI@FEHFHEHIEDG@GBJDF;GEHEHFIFBFJFFFBGBAFC? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243047 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243055.2002258 1107 17 653 29 98M2S = 254 -496 TGGTACATGCATCTTACAGATGAATCTCAATCGCATGCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTATATCATGGGAAACT A)+5C7EF18?'9C,8H-<-GD2-59+EDG,;HI9GC0K,1)5F789A3.-4.)(4<,?=,GFIHI**<*4>EF2E2CF>0.4GE0)>E@110EGCBCD? MD:Z:11A2G15A5T48G1T10 RG:Z:ERR243055 AM:i:29 NM:i:6 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@@ ERR013140.7259970 83 17 660 60 12S96M = 378 -377 ACGCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTG 40&/81&8:/<<79BIILCEL:JKLIKGELFHIKJJJFJFJJLEMGIJLHHGOBGLL?CIJM;KLJEHGFGAFGCDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.8214205 147 17 676 60 108M = 346 -437 ATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAA :;A>;:9685?>@CCECD;@D@H@EDI>CGLJCLFFMIKFKHIKKFHJKCKFMDFHMJJFLJHGKGJIJJKJEEJGJLIJIEEHAJIIDHHEKHFIGGGFEDDC@@?: X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.996298 1107 17 683 60 100M = 357 -425 ACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAA ?>CE?D@HJF:?>EIFFFGGHEIKFBIKGJHJEJIJIHJFFJEIFKEGIJGJBJGIHJGJGGIHHEEIIFIGHIEGF@IIIFEIEGHGFGIGHDGFEA@? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEE ERR243027.1412318 83 17 683 60 100M = 357 -425 ACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAA A7?E@DEIIEJ@GGIDFFEHJGJJHCJKGMIHGKHHIIJHFIFJFJGIFHEJEJIHICDIHGGBHGFIIFIFHHFFD@IHHAFIEEIGFFHHIDHGEA@? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEE ERR013140.3773682 99 17 697 29 108M = 1064 389 GTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGG @ACFHHGIHGCJ?HJFKJJFKFDBIHJEHCEBHHHCHEFAJDF>DFFGFDEB?ADDBEEAFD@;;DDG@8A>:CB=DDBB:CCD@>D?HA42A>?8?/%3@,(=<986 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:29 NM:i:0 SM:i:29 MQ:i:22 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.2317332 83 17 701 60 100M = 518 -282 AAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCT CGD8BHH@AGFKCKHKLIKKG>ILFLJJIGGJILJJIJJIILHIL:LIEMJIIECKGHGCJGLIHMHJKHHIFKJDJKKGHGGKKHIHIIGFGEDEF@FB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EI@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.29762488 83 17 716 60 7S101M = 466 -350 GGACTCACAGGGCAGCACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTT )/4/1429@99+@?%BBDD<;:;=:6?84=<7<=;?7G=?869::6?8B2C;==>0:841>.,5C0?7DB4@@2@FGCBBC5AFCHGAC?BC< X0:i:1 X1:i:0 XC:i:101 MD:Z:7A93 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR013140.11567710 163 17 728 60 108M = 984 356 CTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT :DCCCDDFCGGGCCHHGHKKDJJKFIJIHJKJG=FJIKGJGKJIEKKLKHJMHLHGCGIH?GFFBHDD7BAF>?BHFHFD>D66>7+AECC)CB?.BAB98G<(A9DMHDJI/&F@D&/H(861<:G6..2/39681K36EH2: X0:i:1 X1:i:0 MD:Z:59T32T5G1 RG:Z:ERR162872 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@I@@ ERR162875.14341769 99 17 736 60 100M = 979 342 CTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT BGHFCDGGEIGHGHCJGJJKGHDJFCILHIJJJKHJELJLHKIJGGKKJJLI9LHJILJHHLHKLLGLIKJGLJJ2JJH9@D?GHGEKKLHGJGIKJIKKIL;JLJH44ILGI@KHJIJKII8CKMGJBHGAKLIIJ?HLCIILGDKKHIHIEHDIKGKHFHHDFDBD X0:i:1 X1:i:0 MD:Z:86T5G7 RG:Z:ERR162875 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR162875.20069376 99 17 747 60 100M = 975 327 GAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGG ADCDHGGHIHGGHHCGIHHHIIKGHGLJLIJHMIIJIJJLMILFMILLHGLKJLKNKMIKJLKJJJJMJGJLKLJJHMHJFJKJGMKFJLGHJGGEHHFC X0:i:1 X1:i:0 MD:Z:81T5G12 RG:Z:ERR162875 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AB ERR162872.18011293 83 17 748 60 100M = 488 -359 AAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGT :BDFDI?JEG77D?LLH8KFJGJFHKKLIILIGIJIKCGFILLJCKJGDEIMFMLEKILKIHKIHLJIIMFKLKJIJIGHKILIKGGHGGGHGEEGEDDB X0:i:1 X1:i:0 MD:Z:80T5G13 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.3225464 147 17 749 60 100M = 579 -269 AAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGATTCTGGTG =DD1HEG%@;?7HH28GFCGLD>GDDCCECKDHGGBLAJHEHDJC63AK.BHKFHGIIHH<<7FCE=FE?BDFA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@F@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR243083.371418 163 17 750 60 100M = 1106 455 AGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGATTCTGGTGG ?EEFEGCF@EG@FFIFGHD X0:i:1 X1:i:0 MD:Z:64T5G29 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242979.1294369 83 17 781 60 100M = 468 -412 AAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATA BBFHIIJHKIHJGJFDDIFMGJEGIJGHLGHFKGGIHGIGHKEFFHGILEJGIGHCJHHFJGGGGFGCA@ X0:i:1 X1:i:0 MD:Z:47T5G46 RG:Z:ERR242979 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.21460873 147 17 796 60 100M = 505 -390 TGCCTGGGACCAGGCAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATC E0:ID<=A,5AF/F/H0BEE3LJ&:1EA*G4<:FKAJBC8@CJHH4ICD@,EJ9F4CIHFLH=LEM;AHBJIEKIMGDHDJDGFIJK1CDGCHH/HIEA= X0:i:1 X1:i:0 MD:Z:8G5G17T5G61 RG:Z:ERR162875 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.14588577 147 17 807 60 108M = 571 -343 AGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAA BCCDGIKFF?HGEFAGGGKLJFJHLLHEIGFDFHHHIIKDGGEKDKKFMHHFFMJKKMLJKKGIJIHIJJJAIJIILLKIGIKIKGDKHCCCBBDEB?@@?: X0:i:1 X1:i:0 MD:Z:21T5G80 RG:Z:ERR013140 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.18988851 147 17 822 60 100M = 667 -254 GTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTG ?CD@E?GAJILHIIIJHEJJH:FKKIACJGIHHFKGLLGMIKJKHHKLJLFJKJIKDICKIKDJKKGJJKKIHFFIGEKJFGFEFGHHEFDDFEEGFGF? X0:i:1 X1:i:0 MD:Z:6T5G87 RG:Z:ERR156632 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR156632.4899095 147 17 835 60 100M = 457 -477 TGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGC 2@FGIB?>JIKIJK*I9BEC=:HKLHKIJHKDFJJFLJIMIFKIHHKLKDKJKHGKLLHILILHEMKHGGIGHHHGFFEHGGJKKGJJIIFGFEGFDFDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.21635478 99 17 854 60 100M = 1075 320 AACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTA BBEECHEFIIFIIFHKIAKKGJHJEAKKKJHILLLCKIHHCIH@JFDJIDJJCIIMLHLJKJIKJIIHFLEGIKELKJHGKGIHGDHEF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242971.1689116 83 17 861 60 100M = 452 -508 CTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAG 0>?=B,..4&.9D)B=A--EG97=I;;E1&'::7/:=@-;>3+5BCGGF=HB5I6-F6GGC*+D/1EG=-.2+@/?')?0.C@>E*=A@=2?E3A@:BC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242971 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.1140280 163 17 863 60 100M = 1156 392 GTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTG DEFHIHJIIJJIIIKHIHIJMKDIMIJKGKKHHMMKJHKJJJHIIJGHJJKGICJMLLLCELJJMKFMIIJHIIJELLLFIEGKJMJMHKDGDHFCFCBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.14628028 83 17 865 60 108M = 612 -360 CCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGG AB?E?D@A>>=DBGBGHFB?BHCAHEH>FIIEIFHCIHGGGGJLCEGDGIIFKBG@JJIGIHICJIFHIBIJEKJJEIKFBDKJKIJHIJJIIFJEIH@IGIGBECBA X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR242943.1830749 83 17 890 60 100M = 457 -532 CCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGGAAGATGCTTGAGCCCAG B=D7EG5KCF>GEGBDDAHDFEFFF7FHIKEEEJJ=HIJHII:EDEI9E>GGBHHCLFCDIFCGAEKEIHIGCIHJGGGEGHGDGEFGHG8BB/4.?'BEH9.'HHIH9LIF9@%;AH(:A-0AJ=E=7A,EIF@=;IG<0KH6@F4)H9IG-E,2:G1E;GCAFIBHAGC6FHDGHGGF=CCDE,@A? X0:i:1 X1:i:0 MD:Z:63A36 RG:Z:ERR245028 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245045.954816 83 17 913 60 100M = 517 -495 AATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGGAAGATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTA AD>CGHAFFIKGIFIFHGJHIJAIIHJIGDHIGGJK=JDECHGIGKJHIILHKBIJFGIJEIFH>EK)=BI>)A8FAI1F@K@9FI1A>J9CC3@@2@E8CB)GGILA>+DK0BE-@8J<:I*97CCGD70D X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR162875.20069376 147 17 975 60 100M = 747 -327 GATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAA BEGHGFHLLJKFLLMKLKIJLHLLLKIKJDIJMLLMIJJLIJJLDJKMHLKKKIMKIHKLKMKMMILIGMKKKKLIFHFLJKJJILJLHGGGGFFIHDAE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FFK ERR162875.14341769 147 17 979 60 100M = 736 -342 CTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAA DDFHJHH>JKKKIKJJLGMKKKJIMGIIKMLLJIKJJJJLAJKIIMKMJBKJIKHKKMIDLIJJJLLLJLKGGHIJJMAJILJLHHHHGFGKIFFFIFAD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CI ERR162872.20029780 1171 17 981 60 2S98M = 736 -342 CGTGAGCCGAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAA %2,G.I.6,B6H8@)):=8I3>F*0AAD6B?:=86/.BG5?5=L>DG6L=<64JJ6II-;;>FI>I>EE7DD58C5CM?IDFCL@HDHGFGECFFEHD@E X0:i:1 X1:i:0 XC:i:98 MD:Z:6C91 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BJ ERR243015.17606 83 17 982 60 100M = 618 -463 GAGCACAGGAGTTAAAGGCTGTAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAACCCCTGTCTCTAAAAAAAGAAAAGAAAAG :B@:.D9EBI53,(1:E3;E?74>*3+E=>B>B*-(@1*1H/1?GE+++0+,33:0C-,=BA9: X0:i:1 X1:i:0 MD:Z:4C8C7C49A28 RG:Z:ERR243015 AM:i:25 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.11567710 83 17 984 60 7S101M = 728 -356 TGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAA /36>+5/+ABDF7EF9=DF>D;=C@9CCEIHGHGEBHCDFDH=?BE=A@AF=AGD@F;C>FJBDEFGHFEHFCBCCAFLHH@EJGEDEHGHGGEIGGFG8CBBI?=>? X0:i:1 X1:i:0 XC:i:101 MD:Z:101 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CF ERR242959.1635151 147 17 998 60 100M = 588 -509 GGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATA 6*?DFC8@>7.4ED9-DH=DB9)/I1:C6HC0BG:478)I8C=GDF1B/G*-GFC8+8H>9+D?I:8F2*,:DGIHDAFCC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR162872.1587020 163 17 1024 60 100M = 1273 348 CTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATT EEGHGHJFGKIJKLLJIJIIJIMJNLKJKJJNMKLIJMMKHJKLLIJMKIJKMKJKJOIIKKGKLLKKLMMJGJJLJHILJIJJJLKHHKKLHGGHFCDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.9494189 163 17 1031 60 100M = 1277 345 TTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATNCATTATCTGAA BAFDFFHIFGGFHHGHHKHIHJGHKKJKIIKKLHIIIIIHNIJGILJIHKMIJIJJJLLILJLKKJIILJJIJJIIJGMCHHLELKIF!IHGGEGFED-E X0:i:1 X1:i:0 MD:Z:88C11 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J ERR242943.1490060 99 17 1031 60 100M = 1433 501 TTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAA ?@G@FBGH>>DAFDEI>KGFDBBB97DH?=CIGE@FDED+K@776KDDEGGFGCIF7HDG7>JDFCBE@=CGBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DG ERR245038.1101322 1187 17 1055 60 100M = 1338 382 CCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAAT @AGIEGIIGEGDGGGGKGFFHJGEIGGFHHGIGIIGEHHFGHEGKGFFKGGDHHKHEEJIJJGFJHHJDEIIJJFHHGKBIFJGHFJCJAEIEEDCCCCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR245049.1671108 163 17 1055 60 100M = 1338 382 CCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAAT A@FHEHHIHDGGGGGHJEGHGKGHHHHGHHHHJJJGJIJJFHEHJGHFJEHFJHJHE@JGKGHGIGIHEGFHIJFHHCIJJFHGHHHGKFEHCDCDGCDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR013140.3773682 147 17 1064 22 85S23M = 697 -389 GAGCCCCGCTGAGCGCAGAGGTCGGCGCTGCATGGAGTGGTCCCCCCCCCCCCCGTGTTGGGAACGAAAAAAAAAAAAAACCCCCAAAAAAAAAAAAAAAAAAAAAAA %3%$$$3(+8$$$-&7526&%4=$''%+7.2*,"&1%,/1#$$###$##%%%$$%1$+%$"%$/'##########$$$$$$$$##$#$$&$67%%$$$#$#$#$$6*/ XC:i:35 MD:Z:7G4G4G5 RG:Z:ERR013140 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBCCECUVDDCCCBCBCBCCUIN ERR243091.615703 99 17 1066 60 100M = 1497 530 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTT ?BB@CHEE@EICFGGJGGHFGGGKGIFJHDGEGIDHFIFGEDDJFBFGBHICDKGIGFEIJHIEHEFKGGEJHFIHHLHHJC?CEJFEEBHGFFEFCIFFF@FIHFGDGHECEGI>=>GAGKJGEGF: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@@ ERR243003.852165 163 17 1147 60 100M = 1483 435 TTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGC @?ACHFGFDEEIGGDFFGFFJGGDGFGFJFEGHKHFGKIHKEEGFHGFEIGHKGGJGKKHIKIJHGHIIHHDIHHIEKHG?IIHIFJGGHFGEHEEEF=A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243003 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.1880433 163 17 1154 60 108M = 1476 392 TTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCC :?@@CFEDBBCCCGHGGGDDDIEGJHIJEEJJILFHIBHEFHGKIMJFJJMKJIJLLKIHILKJLMLIJFLKLLLMIJKKLLHGJLLIKGGBH>JFJDFEGIGFC>CC X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EH ERR162875.1140280 83 17 1156 60 100M = 863 -392 TTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAG AA=GGFGHEHBIHDHJI==:?G???EJI@GK?BHIJJIIGJHHHJBBKKDCFLMDB@AILDCIEJJIFG@B@0A?:BC><9=C?@DAG<@;=>CCC>AABB:@=IIIIJAECEHGF@DCAEHIF6>9),<>B9<76$*)=2?5>8:7/*+2& X0:i:1 X1:i:0 XC:i:93 MD:Z:83T8T0 RG:Z:ERR013140 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.20797205 147 17 1190 60 100M = 895 -394 TATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAAT @ECFEGHKJIFHHBJJCAKKLHHGNHMHEIIJEJMIIHFJHMJEIHHKLKMHHGEHDJKMIIEELLMJJHJJMEJLLLLEJHLIIJIDJIIIKEHIHDBE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR242939.1378819 99 17 1202 60 100M = 1582 479 CAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTT =C6:EADGG?;FGCIGFHHGF5IG?H>GCICJD;G?DG9HHHE4@AJDCCEAGIAFD5I,6H=5JAHJ4EJCHK2DAG=JEEDK8836E@ECH///A?=* X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242939 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243035.1352953 99 17 1224 60 100M = 1563 438 CAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCT @D@EEFGHFIG?DGIHHHHFBAIBIFHHEFBJHHHEHIGGGEIDMBBFJGGFFEAGEMHHF> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243035 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.18681977 147 17 1234 60 100M = 1084 -249 AAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTAC 0@75A@E9F:(18K.@;I@2L2E:B?DJHCEJJKL36IIIB7B?CK?*KJI+LGIJ9=JJAL?BJJGJCJGJJGHILGLJICB@AGDD<>ED?9@?DD/=>=0I>=:EA2L7;3ECK5;G=>@MKL/0A2>A89?<2>KF@>L<9;/7>I@4:5:AFD7I@5A@G6E X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR162872.9427750 163 17 1249 60 100M = 1421 271 CAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGAT ECDFFGKJIHHJKLLHHLLLLDIMGILHMDKHLLLEKKHIIDGIILGKJDIIEIK@JHIHIKNMMJIMKJJJDLLLJDILLMI@HKIKF>FHCAFGGHBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR162875.5181154 163 17 1266 60 100M = 1395 228 GAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGG BCHHBGGFHIFJDDHJJLFJJ?DJMIHHKJGGGDGGHB9KGDBF@FKKHBJ6BI@DJJMIJC@IJIIKKLGAIKGHIHKJLIHHGGG=?GIFK8D:CA@= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EFGE ERR162872.1587020 83 17 1273 60 100M = 1024 -348 ATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCC @EED@HGGII@IJKIJIHIHILKKIJIIIKKKHJHFILLNGJJKJLDEMMILGJLLKIJHIMJJHJIGHGIMGKIIIHHHGGGGKIHHGHIHGGGFCE>B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR156632.9494189 83 17 1277 60 100M = 1031 -345 CGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTA 3EDF/DGGHKHHJJEIJKMJJJJJKM/IKGKGH@LMGEJ1MLBHFG@EEEFIHEGFFEHHJKIGGJHGGI;JIJHHHIIIDEJHKJHGIEIHIHFJFGEEGGGFGIHIFE@HIDBFHGGIJHHHFDGFIFH@GECDC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR156632.10697401 99 17 1297 29 54S46M = 1427 229 ACCCCAAACATTCCAAGCACCGACATGACGCTCAAAGGGAATGCTTATTGGCGCGTTTGGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAA DAFCIHHGHHFGCKHFKGIJMDIIJHKGJALCKDDILKCCEHKLLGIJGLIKEIADIHLKLJFEHFJKLLMFGIK?IGEHLE@EIBGLGFDHIHHFCD:; MD:Z:4T41 RG:Z:ERR156632 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@NQVUYXY@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.17780862 147 17 1308 60 100M = 951 -456 ACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTT 5EGFHJHIIDJJHEAFJKJHHGHJJGKKIFGGGFEHCIEEFDEIJJJJAHFFIFLLLLILJHHK>ILKHIL?DDFGA5DA;A7:DD?CFI:BAD@@B@B X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242951.1253490 99 17 1327 60 100M = 1717 489 CCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCT @BEFEDGGGIGFHFGGGJKJGHFFFFHGFHIJDEEKGFHJIDFEDKJIIEIJJDJAJJIIHIB@HJCJGJJBG?G=EGJGEAJKEEGHCEFH>BHCCFED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242951 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR162875.7604876 99 17 1336 60 100M = 1673 436 CAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTT BECF-@EFHIIGHFGGGHHHHEMHHHKKDJIJCFCLKKKKGIJDK9AMJJAELCCJKBHIBCDFJ@IGJKKHBBIHDJKDFIK2IJFLJIGEFHDG8FB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@ ERR245038.1101322 1107 17 1338 60 100M = 1055 -382 ATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCT DAA>CEGGHFHHGDGHBFFKFHHCI>GEHIH5HGIHKDFIBHHAH=JCII?EEHGEJIKAGHGGCEEJCEGIGEEJ:DFIEGGIJFDJHGFEEHCECDE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245049.1671108 83 17 1338 60 100M = 1055 -382 ATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCT CBBB@GICHFG?E7FEGFFIHHIIIJGLIKHHHJHKKFFHJHFAKIJFIHBGJHIGIIJAIJHGEDIJHDIHGEEKGDFIEGGIIGDJFHGHEHEDCEE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245041.487129 147 17 1368 60 100M = 1004 -463 ATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGA ?DCEGGJCAHGHHAJHJEEHCKKHHEKIIBIINGGFDLIBJHHFGKHFFKEHHIKGJIHIHIJIGHGFKFLFIIHEGGFIIDEFGHGHGICJGHIGGEDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245041 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR162875.4511615 163 17 1375 60 100M = 1652 376 TAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCC EA9IHD>CAD6A>K+A=23J>5:?K+0G?17<+G;<79:F=?CCH;<6/J6KCG0JB@HH)EKIFDMBDDB@EKDDGADAABECFDFDHBHBDGFEBE?DEC>@=@:GB@96#E?:42<72%9764;2( X0:i:1 X1:i:0 XC:i:99 MD:Z:91T7 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.4998889 83 17 1385 60 100M = 1122 -362 ACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTT .@2AGHJG8EHJ?JJFHIC/MFGEBAG6J;?@MCKH@FIBHDID7J?E=I;I9=HGG@EGFFFF?CBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR162875.16344032 99 17 1402 60 100M = 1670 367 TTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAG ABFDHDCIFEFGJFEGFFGHBKLKKCG=KKIJFHFLDIFJMCBJHG6GEIIIGLHLGLKKKM@GL4JEKKDLKMEJCJJFIGI>CLFC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@C ERR162872.9427750 83 17 1421 60 100M = 1249 -271 GCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTG ;FA@GAFJJHF;>:GMIEHLKIIJHJLKIJIHHJKJKIMKKMHJJMIIIHJJJJCEKFKLHIGJFNJGKICLLIGKKJKJIKKJJKGIIIEIGGFECGDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.25752000 99 17 1426 60 100M = 1789 462 TTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCACGGACAGAAGGCCCCTGCGTGC B@=>FC/=CEF>G<5CE+HHECIGCHHEFICHH9J/C9><.=;3H.G79M>D/=K.8CFHNB:BEA9G/8:&7E3K9C)8JDH2C2:-H,&.(>./(BG; X0:i:1 X1:i:0 MD:Z:78G10G0T9 RG:Z:ERR162872 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242963.327784 163 17 1426 60 100M = 1781 454 TTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGGGAGGAGCAGGGACAGAAGGGTCCTGCGTGC @GGDBGCGFIED>EJ@DIFDJAEGG?EKG>?J(JIIHBEEJ:D0F,?FG#G9J.FIFHGGF?HEGAH/F82-H9AB98== X0:i:1 X1:i:0 MD:Z:69T30 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.10697401 147 17 1427 29 100M = 1297 -229 TGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCC CEF=8DGGHHIKEKKHHIGELJFHDGGIHJJDKJMKJKKKH=LGJJJKADKJJMFJKBHIFDEGCKDGIKIK;JKCJK2FGJJHFHEIHFGHFG@BFE@B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BG ERR245024.1107845 99 17 1428 60 100M = 1785 456 GGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCC @:EDEFDEHHHIDJGDDGDIE>EEDF?JDHEKIIIIFCIE@H=CCFH>EDHJIGG>EAGI<-FF?FD9A@CD8 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245024 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@ ERR242943.1490060 147 17 1433 60 100M = 1031 -501 TTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCT BADGDG?HGIFFDHIGDHGEGJFGHFKHGADIIJIILHJHGJJEE;BEEFDLIILKB:EIEEHK>IG;AM5FAKKKDKIFK@KBGKKIFFHKICFKFFBDFHC@@GFBGCA X0:i:1 X1:i:0 MD:Z:11T88 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.10970255 147 17 1440 60 100M = 1238 -301 AGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGACGGGTCCTGCGTGCCCTGCCTTCACAAG +>DC7>>0HE,A+37HHA9HIDBA?H.A1A.F8?N5HKDJ9FJ54:D>EK2C2)>I9:=FD=<8IH=GH)/1EF@>;FA X0:i:1 X1:i:0 MD:Z:72A27 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.9078489 99 17 1452 60 100M = 1710 357 ATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGA C@BGFJGJJJJKHGHIJIKLIKJKHJHKKJLGHGIJ=MKHEKF>HJGJKMLIKMKDHDMFINLLBEIGIEGBIBHEFEDI@JEI>JIFKBJHEKJFIIHDGHAGGHIJBIIIKIBDJDHHJIKI>5GGCGGJJHHFHEBFDKFE@;IC=G?= X0:i:1 X1:i:0 MD:Z:9C90 RG:Z:ERR242983 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AB ERR245034.324906 163 17 1469 60 100M = 1786 416 CTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCT ?DGCFDFDHFHGGICEGJCEJFIABG=GBJIFKHGJI@GFFHDGKHH3LHHJJABHHFKGMKKICEFGHGJGHHKFKF9FKI@HHB=FJA2D;:C@DC7@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245034 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.1880433 83 17 1476 60 37S71M = 1154 -392 TGGGTATTGGTATGTGGTGTCTGCTGTGACCTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGG 0%.*1%?0+(3+7%;#'2%8=44222;76%51(02/+5B/:C@<>CA6CA=I8JELF8F.G18.3F)GDEDAE70G--DJJGHK@)+=B0= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243003.852165 83 17 1483 60 100M = 1147 -435 TTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCC 9DBGG@F; X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242947 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@ ERR242999.1133728 163 17 1503 60 100M = 1901 495 AGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACCAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCT >F7ABHDH;F?FAFD08&@L>0HIG5IH=JFHI8?58F58A62;>G) X0:i:1 X1:i:0 MD:Z:34A65 RG:Z:ERR242999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.15752406 163 17 1509 60 100M = 1804 394 AGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGAC EEEFIDIGJJKKKCIKKKLKKLLLIL:IKJMGMLLLLKHIMFIIJMJHLIIIJIKHIKLKMLKKKKLLMKINLLLLKFIEJKJ?JIIKKJIDJJIFBDBC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR013140.17777881 83 17 1524 60 46S62M = 1188 -397 GCGTGTTGGGAGGGGGGGGGGGAGCGGGGACAGAGGGGCCCGGGGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGG &)%%*$$$%##%#(##$$#%$*#-%$01-893-%#11$$2##$"&1*86>=<FGIGJHHIFHHJEIJHEJD4JCIJDJGDHFG9G=HCIB:FGBA8;9E@JFJBHBB8IBBCEC=EJ@B;8;C;@CC6 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.28180864 163 17 1536 60 108M = 1849 387 CAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACTCGACTTCCACGACAGCCTC :B?>=595B?<==??CA>BA=BC4@9B==?A0:C>EB=@AB@>8=>8E;?A@E7;CF;B@=?.GADBA<@9$'17.?2B3C66@386&298 X0:i:1 X1:i:0 MD:Z:88C0A14G3 RG:Z:ERR013140 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.18201416 99 17 1557 60 100M = 1954 496 GTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACC DDCEEJF;HFILHKHLJJIKLLHHLIMJJGIDGIJGLHK9LHJDELM@HLKILMMKIFKLLJELGJJGDEHHKHM;IJAJIGL.BLKDHMIHIIA5GFA? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243035.1352953 147 17 1563 60 100M = 1224 -438 GGATCTCTGCCCCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGC D986>>D=2B&HFI6I/D/A8EB@I3EA5GHG*FEH=C:;HIDD1/G;IFD3EFJ0D?D44I<:=FG;2H3<=@HIH;@>@JIIGH>?EII5CDDDGDD? X0:i:1 X1:i:0 MD:Z:10A89 RG:Z:ERR243035 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:F@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR242939.1378819 147 17 1582 60 100M = 1202 -479 CTGGGCAACTTGTGCCCATTTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGC 0>D/&9C98=AG73#/8.4+0H?H,0'10K@=2G(+<:'C1(20.207D?C2+B?11H&==79J@B:A8>2GH)4@F;H7BB4F=GGHCE0FAGHCBH?JGGE=F;==;1@9<5:.>>0'/,6<=*0;<4:2?=@<>D@B1:<=:?@E@F?BD>8GHBHF;DGGEIBHEECBCD: X0:i:1 X1:i:0 XC:i:75 MD:Z:75 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.25518652 83 17 1632 60 100M = 1387 -344 CACGACAGGCTCCAGCCTCGGCTCCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTC ;C0C/;)@F7,:KK@KGH(CJ<03-G;J.JFF@DC5/:8?GE@DF.A.EA3FI2AGMIMI?E3;F4JBJ@JGEBCK8EIKFHGJ@FDEH=FE7,405,0?GG%E1:D.8115<='E&82A6*IJE53:,*C:)HII:H#D;:D3FKC*8I;368?<0GMHHH?:.-GCJ3<8<-5'+/+BA X0:i:1 X1:i:0 MD:Z:57A42 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR242959.484376 99 17 1656 60 100M = 1972 415 CTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCC ADBGGJGIFGJGGCGKEFJH@KGGJKAGFHHGGIGFIEEIJHIFLGGEFIJGJEGHGKIELFLFECHEIHIHHJGIIHHJGFGIGHHJGIHDGGFDEFB6 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242959 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@ ERR162875.16344032 147 17 1670 60 100M = 1402 -367 AGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCT AC=@>A8:IJKBGJEJIIJFLHJIGKEKMHIEEE9(4986(1$75&8+B:?>EBD>FHFFIGGIFHBIIJMFGIBHHEEGFGCBHDLJHLEGFCJFC?GGEDFGDF@ELFECFEBFFHDJJJIGGFIHHGIFFDA@ X0:i:1 X1:i:0 XC:i:89 MD:Z:89 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.7604876 147 17 1673 60 100M = 1336 -436 TCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAG DE?E:IFD7JGIK>KKJMHJIGDHHKGJEKDJMJMJHKLLKILIJLKLLFDJILFEM?L@KGI4DC=EHIGABH=?9G6F8JFGG@<8? X0:i:1 X1:i:0 MD:Z:73A26 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.9078489 147 17 1710 60 100M = 1452 -357 CCAGAAGTGCCTTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCC CFHD9DDHIJF"*6JJMJJKEAFLMFLBKHCMFJELEEIFHA:KKMFLKFFBJKLCLJLIKLKKHHGJJLFFLGIGJKKFKGIHIIJGHHIGH@CCFE@B X0:i:1 X1:i:0 MD:Z:11C88 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BG ERR245032.1136878 147 17 1713 60 100M = 1416 -396 GAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCT ?BFAE@FF@FABDHABKGKCHIHFDIDHHKDIHKGHGJJFECIHKFEKF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242951.1253490 147 17 1717 60 100M = 1327 -489 TGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGG B4EFFE5FAI7?K5JAHHFJDBKAJGIEIIHHG?ADIGCFIHJK1BJLEGJKG=H@KFDBFIIEAKFHEHIJEFDHGF?IAGFJGIIEEGGEFEHFEFB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242951 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242991.1183757 163 17 1719 60 100M = 2047 427 CCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCC ?=?FDI@@HHGFJEHGIIGGGDHEHFJDHBEHIEEHHJHFBIHHJFHJDFHJFGGHC@IDHIEJJJIJCKHFJKEGDL@DIHHADF5 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.9045126 163 17 1733 60 100M = 1981 347 CCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTC EBHHGHJHIKKKKIKIIKNJLKKJMHJKHJLNLLLLKMJLLJKILKLLJJMLMLKLJLKILLLMKKILKILJIJLKLLKLKIMKKKKDKJIKGGGFF@DB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.16941332 163 17 1735 60 100M = 2041 405 TGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTC BFFDE4EHIHHHGJHHFHJHJKKHKKHGKKKKLKKKILKIIHJMJKGIJLHKLJHHJJMFMIJJMILLLJJBLLKKJLLHMKILLEKEJIGBIII@FEGA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR162872.10053578 99 17 1777 60 100M = 1965 287 CCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCCGGGC BADGDEGEHIBGFFGHIAJKGIJJIJKHGHL7KFKKIJ=GJFJBCKJKADLBBEBJGMKJ;GLHLMECMLLLHH>BEBDI;H=38EEKCB?EK;H(===, X0:i:1 X1:i:0 MD:Z:92A2G4 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@RBO@DDD@ ERR242963.327784 83 17 1781 60 100M = 1426 -454 ACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCAC 4:<9CC1GEHC?69HI0?FD<713E9EFDH=B=HFEGDJ/E9FEE/DDFC? X0:i:1 X1:i:0 MD:Z:88A11 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245024.1107845 147 17 1785 60 100M = 1428 -456 TGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGCCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAG 6DEGCEDF>HJC1BBIGHIE4;DHB>FGIHHICGBB>GFEGIDHD?ADD? X0:i:1 X1:i:0 MD:Z:64T35 RG:Z:ERR245024 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.3514928 99 17 1786 60 100M = 2012 325 GGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGC C?EFGFFIGJEHFKLKJKIJJLDKLLKKIKHGHM6GLK9C@:>GJEMELI1EL:-6IE>L>B>3'2E/BBECJ;DDKINKDG:0H+3BM6@KNJH7B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR243039.1277921 163 17 1809 60 100M = 2171 461 CCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGA <<=GGB40FE;BA>HHI7K:F4AIIABJHGGI:IHD?IHBACCDF@AD<>GADI&ED:)I<9AB10;I/IB6?EF:>3;AGGAHEEI9@9/051EEG@?? X0:i:1 X1:i:0 MD:Z:60A39 RG:Z:ERR243039 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.8706087 163 17 1811 60 41M67S = 2105 373 CTGAGGCCCGCCCTGTGGCGCCTCTCCCTCCCTTGCTGTCAAGACAGGGGTCCTGGCCTCCGGGGCCCATGGTGCCCCCCTTTGCCCAGGAACCCCTGGCTCGCTCCG 8C>@?>=;;4;>40465.<986B1?<5*:%'%).%".,#23$%*+0'$#%"%#)%+,$/.+(#&)#,%&%%'$,)$5$($'%%,&/%.%/5)%( X0:i:1 X1:i:0 XC:i:41 MD:Z:20T20 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.241318 163 17 1823 60 100M = 2171 447 CTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGT =EHCIEH@EICJHK@IHJHHIEFI@EFIIK4AGGKEIBEJ7EC;:IHJF=1?KD.IHG8IGCJ>FHCIHHHFDDF6 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243015.41290 163 17 1834 17 100M = 2189 454 CTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGGGCACCTCTGAGCCCTCCTCACAGTGCCTTCTTCTT <@BB3:GC>H>9II>1FGF26GB.B5:/>93?2&GD<8A2G3:EB3@*B:=8G)A652K40%?6&'&CGBDIHHJJ;FLIGFIIGIIGHBJGJJIJDLGIIGBEHGFJB@DEF@>D X0:i:1 X1:i:0 MD:Z:22A77 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.28180864 83 17 1849 60 33S75M = 1536 -387 GCCGGCCCTGCGCCGTCTCCCCCGCCCTTTCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTG '&1$$/-6%'((&,*%+%$$%.(%/36/+%1;06>?168<>2<;;:@D:79=>;@C9A:D=E9CBAAEACDE9?DCEDFCDEEGIADCBADEHGCGE?C@ X0:i:1 X1:i:0 XC:i:75 MD:Z:75 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242983.836867 83 17 1849 60 100M = 1460 -488 TCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAG AFE@?CGHGBF@F2I-D4HED@@HD7BDGEEB>GDHBCJI5IHGEHE>HGCFEDEFHGEFG=EKGGDFGBAFCGCHJDGCFEHGGHEGCFF@:>@ACH7D@EB@BDDC;BD=?;7D>FDCF?3@%=?;8B@5?8?59@A5B@5D39?::9A?>1%$,-#9.1 X0:i:1 X1:i:0 MD:Z:15A92 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.7109038 83 17 1854 60 108M = 1534 -427 GCAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTC $>;0776;FECG5GGJIJJJFJIIJGDJHJ;FJCFEFCCF@ECA X0:i:1 X1:i:0 MD:Z:0A14A92 RG:Z:ERR016352 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242947.484791 83 17 1858 60 100M = 1499 -458 TGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCC 2EED@IGEHGJFHBHGJHMGLFAGJDJC?KG9LHHIIGCIHHFEJJIIGII9AJLEKHJICHIHFIFJIHKGJKHFFFKGIHDIJHFHJGIEGHCDEB?A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242947 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DDG ERR162872.17554044 99 17 1863 60 100M = 2053 289 CTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCT BFHBFFFFGCCGJJJIHHCGIKDI>KHKKIHLKKCDLHGIJJKKKILLKMJLLJIIJGMHKKIKHLLKIL@LLJJKGLHJIHGL?JIIKBDGEGHCECGE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242975.1004165 163 17 1881 60 100M = 2290 508 GGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGC @>EHGAAIHGHIEIJGAFIFEIGHJHJFKJGGIFIJKHJGLFJIFIGJKKJJFKJIHLFJIKJGFIHKIGIGFGIIIIIFJKHJGGEEDHGDBGIDFDGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR243031.1705886 99 17 1881 60 100M = 2179 397 GGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGC ?@DGFDAHGGHIEIIHAEIEFGHHIIIGKIHHJHGIJGIIKFJIHHEJKIIIGJJIJIFGIFJGCHIKIDJDBHEIIHJEJHIIEFGFDFCHCEGEFDFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR162875.23402552 163 17 1882 60 100M = 2021 238 GAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCC DCHHICIIIJKHLJKDIKHIJKLJIKJLLKLJKHMLIKJNILJKLIMKLMMHKLLLMILLLLHIMIMAILKJIKILLLGKLMLIIIIGIGIIGKCGFGF< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR162875.5605685 1187 17 1882 60 100M = 2021 238 GAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCC BAHEIAIIJJJGKKFCIKHGJLLJLK7LLKLFLJKJGHIKCLJKJGLKLKMFMLKJIEK05FFIJ@MD@N5E;III3IGKLMLECJAFGHHDDKCGD9C< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242971.738250 163 17 1883 60 100M = 2315 531 AGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCA AEDA@HEHHIDIIIAEIGEHHGIIJGLIHIKIHIKIBILGJJHGIJIJIIGJIIGJFJEHIFFLHLHGKGHGIIIIHEIJJJCF?GEAGFDHKGDEHED? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242971 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242999.1133728 83 17 1901 60 2S98M = 1503 -495 GTTCCTCTGAGCCCTCTGCTCTGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCC )+,7@CDG8F4'0>6066E%?/@;9>;5:?.816IK)2//DIBL97;EHC+@0,+2)4?1DG4GC<-E?D442EE3JB6H-%CHBCB;7G,,7F@C12*/ X0:i:1 X1:i:0 XC:i:98 MD:Z:0A16A1A78 RG:Z:ERR242999 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242955.454193 163 17 1904 60 100M = 2322 517 TCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGT ABFFDIBGDHCGHGHFGGDJJIFFHGHIDEHJHHJGHJJFHFJBIFHJHHAI9DAHGHIKHGDAH9CHHAILAJ?JLAFJEJGHIHAFGF9HEG9GG7GHJCE;CBGFGC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.17357143 163 17 1931 60 100M = 2079 247 CTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTG BEDHHIJJHH5J>HEKHLHIIIHEILKLJHLKKLGHHIJIJDEIMIKJMKDKNGM@IIKIKMIILHGEGED?ACDBG5>GG=.E@J8CHEFC?KFIK7HG2&E>D0IIJ=>9D-6FE>ACHIE0<649FC X0:i:1 X1:i:0 MD:Z:90G9 RG:Z:ERR243011 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR242975.806680 163 17 1953 60 100M = 2127 273 AACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATG @AEDFGHEIHJHEFFGEIGGEHLHIHLIIHJFJGGJHIEKDGJIIHILEJFKIJHJGMJIIBFGJJFJKGGKFEFIJKKHEJDGFKBHHJGHGHIDDEDF X0:i:1 X1:i:0 MD:Z:88G11 RG:Z:ERR242975 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR242991.1140440 1187 17 1953 60 100M = 2127 273 AACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATG @@EEHFGEHHJHFEEIDHHGHGKGIGJJHGKGLFHLGIGIFAIJHIGKJDEJGKGIHKJIHBHEKJIJJGJJFFFIDJLIHHEEDJHKGKDJEDIDCEDD X0:i:1 X1:i:0 MD:Z:88G11 RG:Z:ERR242991 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR156632.18201416 147 17 1954 60 100M = 1557 -496 ACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGG 36DEAGCKDKIIIIHHJFJGLL7KKH?K;LLH?IIMKLHIGHK0:LKJ?KA7KBJIIK>EFIIFMHHBEGBIFGLIIBKCIDHHJ@HHCCH>FFDCCEBA X0:i:1 X1:i:0 MD:Z:87G12 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245038.798432 99 17 1958 60 100M = 2312 453 CTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGAT ?DAEFG9CCCFCGFFEFHEGIIHEEHBJCEHGGFHBEDIG7DJEF3HHIFIHHIHFAFFIIJGJIF;EDEGHBFH9CDBGHFC>G/E:??FC@FBC@BCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243087.1122947 99 17 1960 60 100M = 2366 505 TCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAA ?DGFBC?D?DFGGDF>FIFGIHFK@KLGFGGEJDDFFFDFAFAG<><7I8>HG?AKEFEFFILCAHF<6B;IAIHCGBK@<5GIABDDAB5DC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245024 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR162872.10053578 147 17 1965 60 100M = 1777 -287 TTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACA .>@@DJHGBMKCHIK.LJKHHALILLFJDILHBBILGF>JKLIGDJFDCKIGGKEL;LEKIJIKJLBMGJAJJJFIIKKMHIDHGGIKJKIHFGGI:FFD X0:i:1 X1:i:0 MD:Z:76G23 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242959.484376 147 17 1972 60 100M = 1656 -415 TAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGA 6BEFBHFHCGCIHKEIAJJJJGGIEIIFGHEEDICEJKIKF?IJHKFHIILGHGBGDEKHIHGGHFICBHHIHHGIEEEECIHIIEEEIDEIGFFFE>D@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242959 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.2168867 99 17 1981 60 100M = 2205 323 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGG AEGEHEEIGIGJGFJJIKIKJECLCFFJFLLHJDIILKILMLFMHFHKKLMKICIJIMJIDMKLJIJKIIILIIMDHIHHGJKILEJLH@HFCAJFFDGC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BA ERR162872.9045126 83 17 1981 60 100M = 1733 -347 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGG EC?HEBIEDELDIIJIJJKKEIGKJLHMLLLHCJJJDMJKGLKJJIIKJKLDKIJHJKFCIJJLIILGHJJKLKJHEGHIGFKIJKJHBIFEAGHFHGAB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243003.755522 99 17 1982 60 100M = 2281 398 TGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGC ?FDGE>GFDFFFECIIHGKHI4HCHDHDKJEHAFFHIAIGHGHFCEHGHJBGGGDEJFHB5IJGGJFFCGFHHFBGECFIGHGKCEK@?@G?@IFE@;E5 X0:i:1 X1:i:0 MD:Z:0A99 RG:Z:ERR243003 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ZQ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.15198869 99 17 1987 60 100M = 2229 341 AGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTG DD:=GKGFJJJHHJKKHIHKI>HLLGIDHHKLLJJMFLIIGJDJJKIJGGHKDKDJBLHFLJJJGLLGJJ?JDIAKJKMLJL=CIIJEC>IHLGHIEAED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243059.1079565 83 17 1995 60 100M = 1638 -456 GCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTC @DCGFEHG?EHJCJJIJB?HGHGJHIIHIJGEEKGHGIGIHG@ICGJGKKIHIEGFFIHCJGDEEJD?GHHFIKAIEGAHHDIGGIIFHJFHHG?E?DB@ X0:i:1 X1:i:0 MD:Z:46G53 RG:Z:ERR243059 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.4987821 163 17 1996 60 100M = 2242 345 CCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCA DBDFJHHGJIKHIJMKJJDIEKKLLLKJMHIJJLKJMFIIGJJIKINIKKJLKFJJMBJNKJIJKKJKJKKJNJBKKKCKFKHLJMLLBKIHJIBGABFC X0:i:1 X1:i:0 MD:Z:45G54 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245024.420543 163 17 1999 60 100M = 2317 417 AGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACAC ?D@@EH@FGFFBHGG@ECAJFIJH@GDEEGEEIG?GFFGHGHFJIIHGKGHGEKFFJGHDHGGIIFJICEIA:HH;IHIGGHCHHHE:@:C9??BGE>A9 X0:i:1 X1:i:0 MD:Z:42G57 RG:Z:ERR245024 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.3514928 147 17 2012 60 100M = 1786 -325 ACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGC 34F=D2JFAJF*>BBHKGKIEDEIAI@H@LKHJDKCHIGJKHLKHIGGKCHJCLGJIBK=KAKFHEHLKLGKLGEKI?I?GHIGFGBHHHHFFEG@F?DB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.9766143 147 17 2017 60 100M = 1732 -384 GCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGTAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTC HHKGGEFE5FBIHLHHEAFIGGHJEFAH@DFGFGFB X0:i:1 X1:i:0 MD:Z:36G63 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.21458070 99 17 2020 29 90M18S = 2301 388 GCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGGCACACGCAGCCCTCGCCGCGCCCCGGGGGAGTAC @BEFFFFFEJGCJJFGGHIJGJHIIKGIFJFGICCIKHHGEHKFIJJGJJALHLAGIDJEDFGHABFC>>1*128CBC:/1-=&1$1*'($('92%$#(7&%$%,%1. MD:Z:21G51T11A4 RG:Z:ERR013140 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242983.1365156 163 17 2021 60 100M = 2397 475 CCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGG AAEHDDDGHIJHHGEDFJHHHKFIHGIDHGGGHHLHGEIJFHIILIGLGADHG@JGJHLILGJK>JGKKBJBEJFIHEAJHJIFFFIAJAHCJ=GHBEFB X0:i:1 X1:i:0 MD:Z:20G79 RG:Z:ERR242983 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DB ERR162875.23402552 83 17 2021 60 100M = 1882 -238 CCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGG :BFFBFBKIJKLHIIIFMDLKJKLIGEHHIIMMMMJIHIHHINLLLFJDLEJCKL;LHLILJCMJKJKCJCIILGKEDIHKIJJGHBIBHHIGIFHHCBB X0:i:1 X1:i:0 MD:Z:20G79 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR162875.5605685 1107 17 2021 60 100M = 1882 -238 CCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGG CFH>B6BII68FHC>B@@GLFJKFHCA?FIDIKLMJDC:LH9HLKGHFAM;JC2LHJHLILHIMFIKFADCFEKHKIE?HKKDJHHBIBHIIGFEHGCBB X0:i:1 X1:i:0 MD:Z:20G79 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR156632.16941332 83 17 2041 60 100M = 1735 -405 GGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACA ?EEGEHIEFHCJKKJIGGFLHHLKLKILELHCEIHHLJLCMJLMKNLJDLEKKI=IHEKLKJKLIKCLDLLKKNILLLLLHHIJIHDIJHHGFIHAHFED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243059.892087 147 17 2042 60 100M = 1719 -422 GGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACAT DFGDEHEDHEHJHJHFGFJEFKGIKKIBKEDAJIDIJJJJHIJHJIHAIAFIKFG>@JFJJHJGFBJAJIJJHHJHHGLIFHIFF@GGHEGEJF@IDGB@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243059 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FH@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242991.1183757 83 17 2047 60 100M = 1719 -427 GAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAG EB?CDGDKK?KHJGKE:KFJHBBGBJEJ?J?BJK>IHJDH@H?GDDHGEHIHHHD>CADE@EHHEDEJFADFIEEEDGD? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242991 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242991.1577744 1107 17 2047 60 100M = 1719 -427 GAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAG 0@?C7GAGIE@FHAC?HJGK X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242991 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243031.1324865 147 17 2047 60 100M = 1847 -299 GAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAG ECCE@GEIJGEFBIFFJHKHJHAIHIBKJFILIGKIKKHJKJBJAIFIGKEAJKJIKIHGAIAJLKLKGKIIHIHDHGFF@GGHEFDKGAIEIFFGEHDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.17554044 147 17 2053 60 100M = 1863 -289 GAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTG EGGEE?GJIIKLKKLLDLIKEKLJLLLLNKKMK?JLEMBIIMEMGELMJLJLIJDLDMLMKKIKLJLLJIIJJICIJJIEHLICKIK=HFIKJJCHFECD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.360692 99 17 2070 60 100M = 2206 235 GACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACT 8DDB5DF:E=?BH;GKDFK5B?)GAF6@H2CIL?KF;J>JC3E8GHK?@.42I4BGHE7AC. X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.10955775 99 17 2073 60 100M = 2419 445 CGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCT B?EEDEHEFHHHHIHIECJCHGHDIFACGKI7CGAD62LHLCHH6?IG3@CJCHF@K@:HIFLH8G@IHG1KEE@CG58@/HHJ@JJF@C@5JCFAHGF; X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242979.559120 99 17 2075 60 100M = 2431 455 CACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGG @CEEIGHHIIGIEJIBIBFJHGEGAIGOJDGHIBJAIDKJHKHJGJFGDHHEJCGIFEJGKLBFJHGJFHGKJCEHGHGLGIHKIKGMIKHHDGGEFDEG X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242979 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GL ERR162872.17357143 83 17 2079 60 100M = 1931 -247 GGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTT AGFFIIFKH5=?DIJI>JBCKJLLIDHGDLEIMLEMGLIKJLIHHKIDCHIKJIFMJ?JHMIHJJMLBEI@IGBGJGKKJIKGKHIKHF>CBIFFEEE?B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AG ERR243063.1642219 1123 17 2084 60 100M = 2462 477 CTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCA AEDEIGEAFECKHI-ACAGHI=HHHEFKB@HH1..F8=;76D4 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243063.246578 99 17 2084 60 100M = 2462 477 CTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCA AEGFIB@H@IJEHGICJGKIHHGJAI@JBHJDKDJEHHCE>B?HBAKFEHIGIAFHHHH@JHJHAFEEIFKFIHIGDIJJJHHEJIIHCIEFBAFABF=B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.8706087 83 17 2105 60 28S80M = 1811 -373 CGGGCGGGTGGGCGCTGCACACGCAGGCGTCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCAT $$$&$$%&%%#(1-5-(4.=5:C=.&%8%C:F?CFH=GFCG@G?DAFFCB;=G5?.@BDGHACAGGDGCJGDECJHHDHHHFABA= X0:i:1 X1:i:0 XC:i:80 MD:Z:0A79 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242999.1001077 99 17 2110 60 100M = 2438 427 GCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGG @CEGFFGFIGGEFEGDEIAEIEEFIJJBGHFEJFJHKJBGGEJCI=IFLDHHHJJKJDIKLIIIFIID>G7DIHGIGJIIEIIJHGJFKKHGHGDGFFF= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HKC ERR013140.30331713 163 17 2120 60 108M = 2444 431 GATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCGGCCTGGG :DCCA?CC9FEDCGEI@@CFHGIBIEDB?EBDDEIIDIL=>FGE>DCDBFH;@ADBBC;=ADAC==CBBBC1;;A?BC>?FD>BF:DD8>/47=:AB:94;?@9DC?B X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EDH ERR242975.806680 83 17 2127 60 100M = 1953 -273 CGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGG ;CC>7<34<7=;.9??EECCH=FABGGFHHLJIIFHIHILJJJLLLLKIIHIKLLKJIHKGHGKHHIHKJKJGJIJHGIHFEFFFCB@@ X0:i:1 X1:i:0 MD:Z:58G49 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.241318 83 17 2171 60 100M = 1823 -447 CTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCGGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATA CADB=EDBCB,H8GG2:08@HHFAI1;DCGG1HG=@CLAA?IG>GEFG=GHF?EH@>HGFGEDAHIEF9FDECDCCIBAHI>MGF3<0GFFA;6HC==;@6:H950BCG6>:E?BE:CGDFH?CDACDH2HJ;>HGA>CH:I>BD@BC=4ADA? X0:i:1 X1:i:0 MD:Z:49G50 RG:Z:ERR243039 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR243031.1705886 147 17 2179 60 100M = 1881 -397 TTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCT @D:EFEGCFEI@KHJDJIJHKHHGKIKFHIJIHKFELHGFJJJHKHGIIKEDFKIGHJJJFKIGJIJCIKIJIIHGIIIKFGEGEFEDGHEEFHGGFFEA X0:i:1 X1:i:0 MD:Z:41G58 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.1719649 99 17 2188 60 100M = 2533 444 ACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCA ?CC@FGEFIFIHHH>EHGIHH?CEIGCHIBJGEJHIHIHDFGFHGFCEGHHGHKEEGIGDHHJGLGGJIDJJCE=GGGG?IHC@HEDAIIGDIHFGGED@ X0:i:1 X1:i:0 MD:Z:32G67 RG:Z:ERR243007 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243015.41290 83 17 2189 17 100M = 1834 -454 CCCTCAAGACCTGGGCCTGGCCACAACTTCCGTCCTGGGCAAACTGGGGCAATTATCACCAGAGACGAGCTTTATAAAAATAATGGTGCTAGCTGGGCAT @9>7D(.@B&.A111//.(4':-E4=/7,.),'DB=;0)1E<-E<<=3*1$B%'C/D-JH>H1-4*=1+>8DHCEHHHFH9GIJBIHGFDFF>GFJFKAG>IIKKK=GHJGAICEB@ X0:i:1 X1:i:0 MD:Z:14G85 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR013140.20581831 99 17 2212 60 108M = 2526 421 CAACTTCCGGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTG @CEBIFHI>HHJJHIIIJJJGKHIIJIKJIGHGJKHLKIJJKHILJJLFIFGFDFEHJEGHJHGJKLIJFIGEFGLHJKGJJGHBGGG>AHGFCBB?99=EBC=C70> X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.15198869 147 17 2229 60 100M = 1987 -341 AAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGA @BAHGDDDIKBKJ7HDJEKKHLLJIIJKGLHFJHHIHFFIEGCGCEILLHKJBBFKKIIIKIIKJLEJEKGJLFGFFFGIIJJJJFJGHGGIFHEDD?DB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.4987821 83 17 2242 60 100M = 1996 -345 TATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCG DCDFHFIIHJIHIKJKKDIGIHGGHIJBIIDMKHKMIKKMIKLILHJLIJLJNKIKLFKJJGIHJHJHLJKLFLIHIJKJKIKHCHJIJFIHGIEFFE?A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243011.1711788 83 17 2265 60 100M = 1951 -413 AAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACC ?2B=,;EB04@BJ=:D9.40=I;:497E12=JHA;9:00>JA12FB@1D;: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243011 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:F@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243079.862248 147 17 2274 60 100M = 1921 -452 GTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCC CCC@?GEF4H:IE8G0JD269>G6H@/EFE6EGE?=DBII;;A2-G@;GJ7?8H;HGEJGLIFDF@>,H=ADDH:=EF;?F;@FFIG?EGGHF>FDCF9? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.7043507 163 17 2276 60 100M = 2525 348 GCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAA ECHBIJJJIJKHI?HILJJKGILGKLHIGJJJILGHKJEIMHHM?JJMJK5B*ILLINGILKJGKDFIDFEHILEJG=JMCEHAAIJ2JIJ@K8JFFG<( X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245024.1210272 83 17 2280 60 100M = 1962 -417 GCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACG 6FCDCGI:FF@@HGAI@IEE&<@:E@;GE;JJKF2GIJHHGJBH7I@F=IDAIH;BHFAG@BIFFGHBB@F?F@IE:HGEH@:CEDHBFF@FFEGCAH;GDFFGDGDBF?C;IFIFFGB?EAA>?I?;H8DAHHAH7GBA2DIH6HHDEBA>EFE=C X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GBI ERR242975.1004165 83 17 2290 60 100M = 1881 -508 GTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCA DCCD;BFHHDHIGGF@D@IGIIIJEBEHGHIJJFJIBIHFLFIHJJHHGGAIHHFIKICIJKJHHGGGEIIIEIIIHHKGHHDIEGDDAGHGCCBEABD? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243019.556608 83 17 2294 60 100M = 1851 -542 CTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCT D?DEEBFEEECF9DHDIGJIEC;BHHAADIK;@KJIKFIFLHJKGD@HGHHFFJEGHCCJGGGGHKDH>GIFHIJGGHIFEFEGAHHHDDDFBEFGDDF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.21458070 147 17 2301 29 108M = 2020 -388 CTGTAATCACAGCACTTTGGGAGGCGGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAA 920<'/7<1>?48/307$9C721:2$2A/9<226;<66=5?@?:6?AC=>=3DD?-?@E9BB@CBA@;?FDCDC:DEFCACC@FCCC?BBA=ABB@?: X0:i:1 X1:i:0 MD:Z:8C16C82 RG:Z:ERR013140 AM:i:29 NM:i:2 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR162872.23671856 163 17 2311 60 100M = 2618 406 AGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAA BEGGFJGFLJIHLILKDGKKMIMKGMJHHLEHIGLJKJMKJMMIMHJHLIKKKLJLKMLKILLICHJKEJGFJJIGLLEMFKJLLHJJHIIHC?DFEFDD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GKKL ERR245038.798432 147 17 2312 60 100M = 1958 -453 GCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAA BE?GE3FEGGDGE9>KI5HDFGIGI6:EAIG4IID9:GG@J;HHH@EIHJ?@F=JCFFHIJHDEE5>IKJFDDEFHIBHGHFGEEHEFECEGEEID@B?> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FEHGG ERR242971.738250 83 17 2315 60 100M = 1883 -531 CTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACA ECAAEGDGDHG=6DIKAIIJHHIE7@9FH;JHGHIEDKGJGHGFAEFEHJEIJJGJHIJFGECAHIFFFAEHIJIHEIGIDEHFFDEAECEHDCDBBEE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242971 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR245024.420543 83 17 2317 60 100M = 1999 -417 TTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAAC DCEEHEC?F?FEC:88FAA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245024 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242955.454193 83 17 2322 60 100M = 1904 -517 AGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCC :D)8=CE3J??7E+:9I59BEI5H<@E8A?GD2HJHHFHFFHFJFCACAE+IEFD>HIHF=DJDFB?I8A@AFGDEIEFECDDICCHAEE;? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242955 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243059.1325819 99 17 2332 60 100M = 2706 473 AGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTG ?E@CH@E@G@ECBGGHEIGFIIFI?FCIE?CDBEIIHBI:@>F@F@D:IGHHGAJHJF9HFEE8GGC:0?2;2073>C@=@B7980@<8;:=82?2=?;3+>=D??34$1C#%*3<&4)67;39, X0:i:1 X1:i:0 MD:Z:83T7A16 RG:Z:ERR013140 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ABC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.5601349 163 17 2389 60 100M = 2710 420 AGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCC BFFHJIJHIIIIHIEIIJIJJIJHJJIJNIKLKHNKMEIMLGMKFILIJIKKMMIIMIMLLJNLLEJLKILIINHLLLALKKBIHILKJIKJHIFHFFFC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HH ERR242983.1365156 83 17 2397 60 100M = 2021 -475 CAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTT ;BABAEE>DJEFECBDBC:CE>A8C>C>7DBA=BEDDB4=9;:@=;@D@@=B@E.3?972<>6@8=>?1$0:95%5%*1=8;0%4<228% X0:i:1 X1:i:0 XC:i:88 MD:Z:88 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EHG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243035.1445358 99 17 2405 60 100M = 2748 442 ACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTG @CFEEFGFGGGIGEJIHHKFKADLGAJFELIEIHJIHJEELFJIIGKHIHGJJIKGFKJKJJGLHGJHHHLHHIEJJJEIFMKJIHJFFLFEEIAHGF@> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243035 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.22794881 99 17 2407 60 100M = 2639 331 AAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCT @BCCDBEFCFHAIGFHI@JAHK2>F:E;C>HIIKFF>CLCK;&+B2M4CLG=EHE+FH(+(F/'60.JB+),FB04 MD:Z:16T3G14C6T3G2G2G13G3G0A2C3G0A6G6G1G4 RG:Z:ERR162872 AM:i:29 NM:i:16 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.10770274 163 17 2415 60 100M = 2690 374 ACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTG ECHFJHIHLIKEIKJIKIHLKIJIKJKLFIMGLIMKNILHJIJINKJL@KMLIMKJKKIKM?JJFMKLHKKLKJIKNKGLFJIIJMJHLKKJIGJEIGFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.10955775 147 17 2419 60 100M = 2073 -445 GCCATGCGTGGTTGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGAT '9DA,J8DDL:>+JIILCKCKLJ6>LCJBCIKLAEHII;MJJKKEI?KJLKLELIGDMGLIJKHJLGDKKLJ6KLGIJIFJJHLIJKFIIFKJHHFEFAE X0:i:1 X1:i:0 MD:Z:4G7G87 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242979.559120 147 17 2431 60 100M = 2075 -455 GGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCA @ADGG@H2ILDCEIH7HIHGKKEDJFGJIKJHIJGKHHIFHJEIJJCKJIJJGJGHJGIIGJIFIHHKIGKJGDJGGFJIHJGIFJGF@HIFEHCHEEF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242979 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243027.576419 99 17 2434 60 100M = 2778 443 GCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTC >DB@DDFIEFD;BH;?BHFEF?:JECGBHE1;9EIK.F1:G-DAH9I,.=>EF9D@E X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR242999.1001077 147 17 2438 60 100M = 2110 -427 ACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGC 5CJDGDHGCIHIBJJDEGEJIJHKHJLIIIHJHGFGHHJEMJBKHIHIKHNKDGIKIIFIIJIJJIJKHIFKGKKHIGJGHBIIFGJEHGIIDFGDGFCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR013140.30331713 83 17 2444 60 108M = 2120 -431 AGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTG 938:(A@??<8>>>GBGIEFFIGDHLGKJDLIKGFJIGKLKJKCIEJ@LJDIELKLLKJLJFLHKKLJIKGKKHK@GIGKIDIJIHGJJIHKIIF?JEIHFGIHFAC@ X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.474429 99 17 2447 60 100M = 2812 464 CCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACA BAD5=FHEGHFFHIBC;HFJGKD1JIFGHIHJKJIKGKGK2F?BMHE9,HEDK9HFKJFELHJ2BJL.0@FHC1K3DE3ELE=GGBEBIFB6BA9CE9?1 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.12579188 83 17 2456 60 100M = 2147 -408 TCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTC ;DGGIIGJKILJGKJJHGKKJHM?JLEIKMMKGLMLMLKIGJMKJLMELIIJIMIKMIHIJJHEKKGILHKGLKIIJIKKIJJCJIHIGIIHIFFFHDCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243063.1642219 1171 17 2462 60 100M = 2084 -477 GGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTC DF8AH9?GHHCGCHJBKAIK>HJDC=HCIIJFGGAEJGIJKCADDIAI:IC8H9HDB?IG@GC=;87GAHB=G>H;2@GEHIFGHBGGFFFFDGDHDDB: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243063.246578 147 17 2462 60 100M = 2084 -477 GGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTC A@G;HFFFFF9CHHHFDEE@3HJHI/HIIDJJH?DGDFIJJHIKEIGIHDKEGCCDE?EGEGHBK?IFFABEGJCH2@GEHIEGHHGGF>HFGDDB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.7043507 83 17 2525 60 100M = 2276 -348 ACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTG KCJIE;J@>LIKJLLIJMKIFLHKJLEJIEKHHBHKKIGLLKILMIGKDHGMMGGHGHGGJHHGHHJHDHFLIIJJGJFIFEEIGGBHCDB X0:i:1 X1:i:0 MD:Z:39A60 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.20581831 147 17 2526 60 108M = 2212 -421 CTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCAAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTA @EBBBAC@DG@C@6FCHEEDEBH=B>EECCFDGBCC@FFFHGGKDFGLEKFKDFFI@FFHFFFEIJFFIAEEEEHDDHHGGFJIIIHIDDDIIIJJHGFEHGCBEFB: X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.1719649 147 17 2533 60 100M = 2188 -444 CCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCT DEFHGFAGHHJDJGGJIHKIIFH>LHHF<9CFEGFEJKFEJJJHKIFBGFFHIKFHEEIFGGFEEFEICDHFJHHJIIJFJEFEJIIEJFGIEEEIEDF@ X0:i:1 X1:i:0 MD:Z:31A68 RG:Z:ERR243007 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.5990783 163 17 2544 60 100M = 2843 398 ACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCC BCFGFHFHGGFIGHJIGJIIBIHHIILGIFLJGIKIIIFIEGHJIIKIHIJHJIJJJIIIHGLHMCJMKJJHIILFKKLHLKJJ?FHLKHLIKF=D=GED X0:i:1 X1:i:0 MD:Z:20A79 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BCD ERR243019.804639 83 17 2558 60 100M = 2190 -467 TGTCTCAAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGC DEDIAFDFFFCHJCBCGKDJMFGGAFHCLFDDEKFGH@FGGHHFEIDIHIICIJCJGFFIGJGJGCK@HGIGFHEIIHEGGHIGGJGHIHIFFCBEA>D? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.17163139 163 17 2564 60 100M = 2828 363 AAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATA EACFFGJHHIHI3IMIGIJI>>GJIJKKJ?JKBJIJHIJIHIMHMJJMKJJAFKMJKMNHMKJM=GKMKINLLIHI>LKGKMJIKGIHJIJGCIJ?HFD- X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GCDEDB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243019.1623189 83 17 2569 60 100M = 2285 -383 AGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCC EA?C?F>=D@;FBFBGFD?B?AH8H?6@G4JDIIGEFFF:C9@@CDGHCCE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR243091.852212 163 17 2575 60 100M = 2967 491 GAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCT ACDHFEFGDGEJGDIHHHDIHDEGIHCFHHD7=:@<&I4L;C?/AJ9JK>J2DHKAK5,H29=,=0,E9?H.GKJGE78&,6A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.20693133 99 17 2588 60 100M = 2892 403 AAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCA A:CEECDFEDGGHGF@GE<=D2F?BF?>HICFH7EJIKHHCIGFEF@BJHFKJGEHDCLGEHHIFGGHHIGIFDKDIJGEJJHJGJHFKHFDF>JEE?GDCEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.12418699 163 17 2634 60 100M = 2962 427 GCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCC BDGBCGEHGHHIGJGHFJHIIKDIHHIGIIICHKJKFKLKKF@KMDKJJKJJLIEHMK=KIJJEMMJKIHLJJKJILKJJKHHJJJFHKIIJAIGFH9E> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@JD ERR013140.12984374 147 17 2636 60 108M = 2382 -361 TTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCAT '??98:CD@B<CDI@CCF;>DEFCACDD?@BDCFBFFEAB?>BDGACDDECDCEDFAADDFBB@CHFJICIJIEECDFEADGDHHCAJBDBDA>CA@9 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.22794881 147 17 2639 60 100M = 2407 -331 GGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTT 6?.97*GGD:-:810C?IIEJKBCFDJ>HCFFGEIFIGJ:JCJJE@:2>@2+4B>E>BBDDDAD@DE:=D9CGD;'A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR242943.312088 163 17 2694 60 100M = 3037 442 ACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGT ABEEHHIIGEIHGL9FIIEMEFGKJHJIGKEJGEHDKJIDFDIHEGIGFGLKEIGHJJEGJIACGDHGFJHCHIIIIFDELGIF9HFD;EKFHFFEEFC. X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.5443750 99 17 2699 60 100M = 3006 406 CTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATG AAFG?FE9<3/IDDJIHBDEIL5;JHGH:/>LJHD?JH@F*CJ8H@.GII>IHB:EJL82B81I7?BA?E;8H>;J:CHK@2(HDH.7C/47.48A(+8; X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243059.1325819 147 17 2706 60 100M = 2332 -473 AGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGC 2DDDGDFFH?DIIIGHGJAHGJJ;JJ8HJ>IIBBIJIIJE@GGJHIGIHI>FFDJIEHJFKHJJIH@IHFJIIKFIGICHIHBHHHGFHJFGHDHFFAB@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243059 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR162875.5601349 83 17 2710 60 100M = 2389 -420 CTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTT D@HHHEGEJJJKGKDKJLIJKIJHMGLIIIKKIJMIIJJMIJKJKKOHHGJI@MMIHJIJIGILKHKLKJGLKKKKKJKLIKIHJJGHIEIHGFGDHCBA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR243019.480835 99 17 2711 60 100M = 3135 523 TAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTC ??GADDHDFIHIHFJGDDEHIHHGHIHEFHGDEGF?GEHGJEEGHGGFFBFEEFEIIJHH@FFKEIHKIEHHGKHGBIHIHFFIHGHKCGKDHFFEFBCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.13634813 147 17 2713 29 100M = 2414 -398 GGATGCAGCTGAGGGGTGCCCCTTTTACCATCTAATCTGTGCCATTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAG F,7?1D.JK>H@80DJA3.K6LJ%7IHJH85ADIDFB8K8300(66AAGK;;:EEE X0:i:1 X1:i:0 MD:Z:23C19C56 RG:Z:ERR162872 AM:i:29 NM:i:2 SM:i:29 MQ:i:29 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR245049.1543898 99 17 2735 60 100M = 3077 441 TCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCC ?DFABEFFFHHEGGJHIHJIHHHEFGEEJHHIHJIJEF@IGGGJFFFKHKCFHIIIKFFJGHHJIHEMAJJGIGAKIJHGFE5EII76IDG>;?FEAHGIIFFGFE@? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243035 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243027.576419 147 17 2778 60 100M = 2434 -443 GGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGCCCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAG :DCC@>DCC1HBEEBE=>/;:4;>*E?FBGB-IGEC@>BIHH9#F0H+2?@FCI4A>HAGHBEDFIJDHDEDDDJGI>BAECA X0:i:1 X1:i:0 MD:Z:43A56 RG:Z:ERR243027 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.1633327 83 17 2786 60 100M = 2618 -267 CCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAG =DBCJ@DHEHGJHBIEHHFA':'>:;BHHLKJKJ6=BH7FII->G9DF5?.;*7A0?== X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR162872.17163139 83 17 2828 60 100M = 2564 -363 AGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACA 4CGHB?HDB8CJDKHLJJJBJHDJHJJMIKAFIEMLKJJJIMJKGIILLMJFJIKJMGJIMGDIKKJHLLHEGFKJLHGKKHGGKJIII?EEGGCCGDEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.20228886 99 17 2837 60 100M = 3084 346 GAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGAGTGGCTCAGATACAGGGAGGGGCCCACAGCTCGGCCT @CG8DHF:=7?5GBAGDGAL9I9JB,BIHHH=5B,8;4M./MK7E/.GL(B.*.88J1FBFJA6CDB;H57L&K:)(GI1B405B.-17) X0:i:1 X1:i:0 MD:Z:62C19T17 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.5990783 83 17 2843 60 100M = 2544 -398 CAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTT DFEEAFH@HGJHLHKFKJLJLLJKKIMKJFHGIJLIEJJJLGLKDNHCKJKJLKLLEAILHLHJHKIFHLLKLJLEHLKKKKHJJKKICJJGIGEGIEBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR162875.26247502 83 17 2858 60 100M = 2581 -376 ACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGAC HGGAGICIHGJJEHGJ@E>?ICJAJ@EIIDBIHLBF@IHKI2DKF=EIHKFIHLJDK=CHHDDJ@G:>@C?F;,CGI8G;HDHBJ:BJDGHJ>LIKA*@GIIF@BF::FF1JJBLCJDKGBJJJIFFJIFIIJDJ:IDJJHJGDFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.13732136 163 17 2900 60 100M = 3298 497 GTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCA DDHBIJIHLHIHJJLIJIMILKKJLGJ:JKLMBKLJLM?AHFJGIGALJKLHIEIFIEHC94ACB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR162872.24480599 99 17 2922 60 100M = 3229 406 CCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCG BADEEEIHHFADFGJKEJHHGCHEBGJHIIECGFKJLLIBJFJGE<.KFA;JHMHBGCFCJMKC7;LKI49J@>1KD2G)BC1AC>KAHF77+4HC3:@$ X0:i:1 X1:i:0 MD:Z:99T0 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243007.1511398 147 17 2951 60 100M = 2622 -428 ACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGG -;EDIBBIHHFEEHC?DIJ:IIHJIHCHJB2G:HIELHJIJHI?HCHEIDJGDJFIHHEFGIJIIHIEIIHJGHIJHHHJIIIHHKIHHHGGDEHFFE>@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243039.1477734 147 17 2955 60 100M = 2595 -459 GACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAG @BCHBEAED@C8EIH7EJICIIIGFH0GGKJIJGLGAEIIGGFHEGDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243039 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR156632.12418699 83 17 2962 60 100M = 2634 -427 CCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGC 6:FFAGIJHKKLMLJKLKL;9KLIGIGLJIJKK>JKLFDMMKLHJKFHKLLLJMJLHLMFJKKLNKMKLLMKNJ>JIKJIJHH5KIHFLH=JJJIHIECD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR243091.852212 83 17 2967 60 100M = 2575 -491 GGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGA AFBAE<@GIG@H7I@5=?HCIEFJDHG?DBFAJDHJIFE0IDCFJIJFI@HAGJIGDCHIHGGJFCEGIEFHHGFHE?G>GGBGDIEFG=B>GHA=FFE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243091 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243043.1629476 163 17 2977 29 100M = 3421 543 TGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCC ?E?>CEEFDIGHHFGG>FFGJEGJGFJHFHGECHG=FGJHHFGIFI@K>IEHFC8DAGLIF>JBHE:AJHH:I:G*>BCDCDB8GHF6.5@FF10;@E92 X0:i:1 X1:i:0 MD:Z:99G0 RG:Z:ERR243043 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@BOU[PL ERR156632.1508798 83 17 3006 29 1S4M1D95M = 2587 -518 CCCCAAGCAGCAGCCGGGGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTCCCCAGATGCCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCT <'&*(-+/?*88'-%%(((+KB/N.G)9.5E39>/;,FBHLI?CKH=BJ?FEE==DA MD:Z:4^C6C0A2T1T36G8G36 RG:Z:ERR156632 AM:i:29 NM:i:7 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@FEIG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.5443750 147 17 3006 60 100M = 2699 -406 CCCACAGCCCCCACCTGGGGCAGGGAGGAGCTTGGGGTACAGTGCACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCT @6F1-8/B%#K/,H/4A3EA9@KI7.1F049E82))G61;/,-H*C<)9*JB;.*E=;;9/.E8IGG>H*K3GJ6F256:D6:AGJ6H:CA;L5KK;@5IGBKB;:>5KHJLKDGHMDLJJKIJJLGLJJJLIKKKKHIKHIKIHHJGIHDD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242943.897194 147 17 3015 60 100M = 2661 -453 GCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCA +EF0D..G8E:D9FIA?GB;3;ECG:HG@2DBJ/F;;;CG?GFC;7H@*DFA=I+FGGJE?IILHIGJGKIGJEJIIGHEFJIJFHKGGJGFGHEIGEEA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.25542568 99 17 3017 60 100M = 3110 192 CACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGG BDDCHHFFEEGJHBEII0KGKEGEECF?D4?H9GGHH@:I;EFHB=GBI6GGE<+AIEGJBDI:9IGDJAKEHEJHCBIGHJDGHGFJFHIGHFAIFFJGHGIEIGHHGFEBBD? X0:i:1 X1:i:0 MD:Z:62T37 RG:Z:ERR242971 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243039.71589 147 17 3030 60 100M = 2654 -475 GAGCGGCTTGGGGTCCAGGGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTT .2*D-E;*DH>GCHF

,+@3IEA;IBAJKHHDKFHJIKDJJDFKI;IKIIAIHIKIIBKGLJKLJIJHHIGGJGKIDKEHHJGHGHIEEBAGHB X0:i:1 X1:i:0 MD:Z:9A90 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243063.161207 99 17 3057 60 100M = 3124 166 CCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGG AAFHGFFFIFGIGIGFHHHAJHIHGHIJFKGFHICDJGHIGMFHGBIJEKEHIIFJJHLHBGIIGJJIIJKHABIIKHJHFFHIHIMIGJEDJFEFFBFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR243007.788439 147 17 3067 60 100M = 2789 -377 TGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTC >=4EGDHEACGIHKIKHHHHJKGIIHJCIIIJHIJG;LIHHKGLKIJJHIEJKLFMGJGJKGGGJGHIJJFEFHJJIJHHIHIEIHKHHJEFFFGIFEC@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR245049.1543898 147 17 3077 60 100M = 2735 -441 CCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAG CF@GAHEHDEJFHHGHJFJKHHG=KFDKHHIIFKIKEHACHDJJFJEJBJKIIHJHHHJIFDFJIGGJIHIFJHAIKGIJFHHFIKIHGHIGFIGGHGDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR243031.650799 99 17 3080 60 100M = 3507 526 GCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTG ?DBFHDH?DFIBCIEGEGDFHAGCIIIE=GHGGFHIDD@IHCHHJDFEADDE>C8EGG6:JIEL?GG8BI@G2EGIHGI=GIHEIDKJDGJIFEFC@>BD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR162872.20228886 147 17 3084 60 100M = 2837 -346 GTGGAAGTTGGCCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCA 6+0GEG;HD?)'@8K0/GJ89>B=:GILFGD3HB<LG>GC5GBGD?7CIEECAHADBFDCBDAKFGEEGFDEFC@AED?DDDD'>>>CKGBF?HE@EB@CF>FGDED>@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243051 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.1328730 99 17 3121 60 100M = 3494 472 ACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGG BDHEHHGIDEIHHAHJDDEFIHIDAKI<<5IJ;JKEB3F=CFCJHIJHEJIKCLFLBECD2GIEH5A4FCH53= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243063.161207 147 17 3124 60 100M = 3057 -166 CTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCAC EDFGEDEJGH@HIBCMHKJIICHGGIFIGKDGIGIFGCKGIHGIHFJCHIJJHHFICJIGGDJDFDKGHIEGEFFFFGCHEIEIEGHDEGGGC?EEEFC? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243027.47729 99 17 3134 60 100M = 3547 512 GGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCAC >?FEDFFGGIHGJGAJEHHFHIHFIGFJHHJEJIDHKCIIJFKIFJHFJBGCIEFIHIGJGFEAGGJFFLHJHGAIIBIFKGIEAGG?IIFFDHCFDE9C X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243019.480835 147 17 3135 60 100M = 2711 -523 GCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACG EFB;GBGHGKIHHFJBHEBIGJGHHHJLIG?BFGGDEHGB@:H?>?=H@CGHEBJDHDFCEEGH98AJHB?GAGEEJ9EDGHBE736? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245041 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.19273677 99 17 3143 29 99M1S = 3488 443 GCAGGTGACCCTGGAAATCCAGTCCAACTGGCAGGAGGGCATTGAAACTGGCTTAACAATAACAAACCATAGGCCCAGCACAGTGGCTCACTCCTGTAAA A.<='.HF8B@>I45)D3I.,8&;J;(174HBHEE). XC:i:99 MD:Z:16T3T5T8T15T4A3G0T2C10G0G14G7 RG:Z:ERR162875 AM:i:29 NM:i:12 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@Q@@ ERR243031.386955 163 17 3144 60 100M = 3511 466 CAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATC ADHDDHGGGGIKIGEGDIGHJEIGGHKIJDJHKIBLIGIHHFKHFIHJJGDGEDHHEHHJCJBDFDHIEDGGBH:JCGGIHIEJHEGEFHAGC=D@C3=B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR243091.881299 163 17 3174 60 100M = 3491 416 CAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGA ACHCFJFGHGEFJFIHHJIJGEFEIHHFDJDKHIGHHGGEKIIGAJJIHJHNCKHJJJHJCKIHJAGJHJIHGKJGHJEEEIGFJIIHHHDGDHEDBGEA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243091 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243067.1030440 147 17 3191 60 100M = 2824 -466 TGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAG @?BD=<9$=>-74&CI@7FIE8AHA5E>HFIDFKJ8H0BCDHJFGHHH=ACHEGGDHEDD@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.18600710 163 17 3209 60 100M = 3375 265 CCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCC EBFFFKIJJCIIKIHILILKLLLJIDKJGHIIGJLLJCKKLKLGIKGKKLKLLIKJLEKIL2LJKBLKHLIHJIJIMJLKILEHLIFLJILFGJJEHGF3 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR156632.13236661 147 17 3218 60 100M = 2887 -430 GGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTG >ECDFFGGBKJKGK@CLKJHJJF;F< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.24480599 147 17 3229 60 100M = 2922 -406 CTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCT B7H:=HFGAGBHICJCLLHGEHK>?KHKIMHI:MEDGFLBIHIEIJLJM=IGLLJFHLKIKIJHLHFIHKLJIEKIKK+KHHIJILJAJHGHDIAAFEED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242963.1107552 1187 17 3234 60 100M = 3565 430 GCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAA @ABGHECGEFGGEJHIHHFFIHGDKGKGHLHHEHHHDJHEHIHGLIKFKGCJHK=ELFEKHGKFHIGLJJKKHJGGIGIGMKEGHHHHFIG?BGF?EF?C X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AH ERR242963.383553 163 17 3234 60 100M = 3565 430 GCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAA @DEGGEDGGJGGGKJIHIFFIHGDKHKGHLHHEKHHDJHHHIHIJEHHKGEJJKFGLFEKHGGIHIILIFKKJJGGDJHGIKDGGGGIFIG?EIF?DEAC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CH ERR162875.6771266 99 17 3240 60 100M = 3423 282 AATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATAC ABEEDEFIHFHIGFHGHHKHKKHIIG>JIJGKHIHLIJIHJIMKHLKNJFN:HLHJMJJMFLKKILKMMK?GIGIJHI@GFGJELEAHFIFKGGFBFCC? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243015.596677 83 17 3240 60 100M = 2861 -478 AATCGCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATAC 5@C>*8FI6D:EBAG:GHD>F8;FK;G>FIIJH:0C<9IIAAIF>J>JIFJEE?CHHJD@FCGHIFJ@CA;G@:GFG@EIDCCCBC@B? X0:i:1 X1:i:0 MD:Z:4C95 RG:Z:ERR243015 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245032.287858 83 17 3258 60 100M = 2905 -452 GGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTG CCDGCEFFHIAJGGFG>JCKHFKIIJGLGFIHH?HJFIJ>HHHHDLIJKGKEFMHFJKHJEGEIIGAIHLEEKDGEFGG@DJEEEGGGFHHFJGGG@ED@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR245038.1772750 83 17 3261 60 100M = 2917 -443 CAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTG EEDEFEDFIBGGBFK;DGHHGIIGFIJCHIGGGEIG>IJIIHJGHIFHFEJHGHIFJECDGHHAIGIEGJCEGEEGEEIDFEFGEEIHCIFFH@EEBDC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.4053670 147 17 3280 60 100M = 3038 -341 GAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCA DCEFGFCJIHCIGIFKL@LKKLKKEKL=LHHIIJMKHLFGHKKKCJIMHGMGGHGIJIGMHHHGHIHLHKMIKJCIHKIHKJCHJGGIFJFFFCFFBAFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.18994301 163 17 3289 60 100M = 3627 437 AGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGG EFFEIGGKHIKHKKKKLJLKJJJKILJILIJJJLMLDJLKHKMIKJJIEHIHKJJJEEHH?LKCKJDJLHDLLJBLJGJKKHHIIIIHKKI?JCCGHBGD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@II ERR243003.1151913 99 17 3289 60 100M = 3442 253 AGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGG ?EDBEFFIFGGFJIGIIHJGGGGEFIHEJFGHIHHIBEKHDIHDEHIGGFJGFIFFGFFLJIIJHJBFJHFJJJCKGGJLHHKEFFGDIHFJIEAFGBEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243003 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG ERR243039.1531670 99 17 3295 60 100M = 3652 456 AGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCT ?CDDDEHGFHFDGEHGGGIHHEFHHJHGHCABGIEIHCGHG>F@HHGHHECFDJGIICEFBFJDFK0FBGGDKJEJIEEGIGGIEHHFAID38FDDADE< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243039 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.13732136 83 17 3298 60 100M = 2900 -497 CCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAG =FHG?JAGGA=G8K?GJ@=EFG@LEDAAGNJHMEEHIHIIIJHH:FF:HA@EKDL<>?FIJJEKEFKB@GJKIIHHGHCGKJJKG?HGFIHHEHGGEFGA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR162875.12766080 99 17 3309 60 100M = 3630 420 AACATGGTGAAACCCCGACTACTAAAAATACAAAAATTAGCCTGGCGTGGAGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACT BB;EEG(>HFFD,F>24*HHG4;GEII3;@IDD3??GDFJ4AF;/K1BK:)B6G2GFE9K2G98IF,J?H=JK=2GI9K.-<98HJK0:9-=4$1;/12%27+28, X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242963.128219 99 17 3359 60 100M = 3766 506 TGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGC ?EAE?GFFHHGHIECDGJFHGGHJDEDEIHFGAKKHJHKBGFGJDEFGGHKJJHKGHIJIJIGGLGJBKGH@DBIJ8I==FIIFJGIE@JFG?G>>@CB> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.18600710 83 17 3375 60 100M = 3209 -265 TCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAA -EDHDFJ@DKH@JKHIGJJGCMGLEIFL9GJ:KDJJAIMAHJKIJLJELILLLDDJIEIKKHBJKLMILJJHGKGCIIKHLIJJHKHJIIIEIFGEFGBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR156632.14578469 99 17 3384 60 100M = 3677 391 CTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAT =A7AH;9;.55-+.&132$*8344:$:)$8807;:B<>A=@=A;@@:CDB@EDBCCIGBIFIIHJJJHGFFGJHIDCBD> X0:i:1 X1:i:0 XC:i:66 MD:Z:0T65 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243043.1629476 83 17 3421 29 100M = 2977 -543 GAGGCGGCCGTTGCAGGGACCTGAGACCCCCCCACTGCCCCCCAGCCTGGGCAACAGAGTAAGCCTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGG B.C;((:#?3H.3*.11-1').:.8,&#'/'9J1;.5B7((F004D9/GHD0>D>=/;-;EG6#F@2E9/>/3CFCFDEFFEFEFGFJCJDHHFFF@E@A MD:Z:5A1A8T2G6T1A1G7A1T22A36 RG:Z:ERR243043 AM:i:29 NM:i:10 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.6771266 147 17 3423 60 100M = 3240 -282 GGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCT @@0AF,6EG4<:.>>F.?H6F8B.4:1@5JHGEHDCBBFKA?KG;A:JEA>HGHIGIHHIHIGIILHLHJKIGGGGHFFE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR243067.219795 99 17 3430 60 100M = 3486 155 GTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATT ?CAFFDHDHFHHIIFJEGIHGAIHHHHIIGGFIIFJIGHIIJJGIHGKHLCBHIFFKJHJFIIJHFHGFGDIGGHF9BH?A7G9AC@HDI-FG9DB9A@> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.12181062 163 17 3434 60 100M = 3613 278 CAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCAT DDHFIHJJJKIKIGKJHBKKJILLGIJLKKINKLKKLKJIJJKMJMGHJKKJMLLLJLLMKJHJJJJEIKIJ;@?EIGH@JJGHCIB?HAFDC1>@H3C3 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.15307937 163 17 3442 29 98M2S = 3853 510 TGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATAAAACAATTTTGGATTTAGATAGAATATCATCTG BEEEAEIFH@K?BIGED@HJ@/HI9LIKJJCHAEKFGM?EJ:CJCC=EI:FKK<4FB@H=H=45)-*;I2+.;IGBB@A7I2:AFI==73B2G9HGFEHL-IDDHCCDEI>?DFJEDIGAEEEJ/5FGFGFGGFFFFIHIFJEHJGGHHHIJKHGJHFHCGIIFEFFHIFFGC@ X0:i:1 X1:i:0 MD:Z:52^A48 RG:Z:ERR243003 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@efefefca`_]]@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245041.246570 147 17 3462 60 100M = 3137 -424 CCAGCCTGGGCAACAGAGAAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGA ?8/5F*9EA40GD0G8/:$DC:2G-C;7A1.;@E@E=FDD7EFDCHKCHAIFDGHBFFIIG=JHJ?CGJICF5GGHGGKEIGBHBHGCFCDEEAGAGED@ X0:i:1 X1:i:0 MD:Z:18T81 RG:Z:ERR245041 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR243027.1264030 163 17 3470 29 40M1D13M1I6M1D5M1I23M1D9M2S = 3836 465 GGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCAAACATTTTGGCTTCCAGATTCAAATCCCCCCTCAAAGGATAAAAACGCGGAAATTCAAAG A?FGFGGIGLFEGJGHIIHHFIJJIHIFIGGGGFJF&*0>.*J*1G>F1?**6.)1%/G$/<%*/*E*(I4*)0B+=&-/-*7545)*55.GG)C./E*) XC:i:99 MD:Z:40^C1C17^G2T4T3G0C7T1T5^T9 RG:Z:ERR243027 AM:i:29 NM:i:12 SM:i:29 MQ:i:29 XT:A:M BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IEb@@C@@@@@@A@HL@JfC@@@@@@dICcL@@EU@C@@@@@@@@@@@@@@DC@@@B[@@ ERR162875.18637663 1187 17 3471 60 100M = 3780 408 GCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGT BDEDGHEHLHIHHJFKJJ:GKLGKDHEJCIJGJJIJ=CHCFHJGGGGCH@EJIFDGK@C;DJJ8:?KIK;;LFE=E4<-I8AA4C=F71AIF8H9=FC8, X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.6808869 163 17 3471 60 100M = 3780 408 GCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGT DDDFGGJHKGGHKFIKJLLGKKLIIJIJIIJHHJKICBJJJFJAGIHBLGBFIIIKGJ?CLFFIJJKIKDCGKEHND6DDICEHHAIDBIJIFJEIJDL@FFCFF9HH>EEBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243067.219795 147 17 3486 60 100M = 3430 -155 TCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGA /B7E4=5:DGFFFFFEFFFEHFKGKFIIGGGHHHJJJIJKLIGHJIHHGFIIFHKGJJFIIKGEGEHFEAJAJGIFFGHFIHLIGIEIGIEIEEEDHFDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR162875.19273677 147 17 3488 29 6M1I93M = 3143 -443 TGTATCAAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAA +CC-*98FHHF;I@(:DC1FIJ:J16A8>)2J3KC3G;ALH<@LF61G6ICB?CI;DACEIBIGG4JDAI:GHGJDB>JFJEBIBC:BGFHHHFD:B X0:i:1 X1:i:0 MD:Z:3C95 RG:Z:ERR162875 AM:i:29 NM:i:2 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@eggeZh\CT^[HY@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR013140.22233344 163 17 3490 60 108M = 3784 401 TCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATA :CEDCDEGGHHHIIIIIGHHEHFJHHEEEELJJEIILHDDEKJIHIJKGJKIEKIHGMGGFEFFFI>LCFHLLHF?DIGEFFJGCFE;HEE@AGCJHIIIIHCF?F>@ X0:i:1 X1:i:0 MD:Z:97G10 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.22586072 83 17 3490 60 1S99M = 3226 -362 TTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGA .*71578ED=H6?H>D?,DLFJ7B7A=II5C=@JGHEAFIHIGIHBHCDHBL6EAHKB@IGCCEBCDB@CIJDCHEDGHGHEIECFFGI@CGFHGEBGE@ X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR243091.881299 83 17 3491 60 100M = 3174 -416 CTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAA C5;=CAAEFDFEEEEBCI;JFIKHGHGHIIKGEKGJIGGIJG=GDIKGFIHIJEIHJFFFFDDDAI>IDJDFGFEIFGHGIFGFJFIDFGEHGGDB@A@? X0:i:1 X1:i:0 MD:Z:96G3 RG:Z:ERR243091 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@PSRW_`_^ ERR162875.1328730 147 17 3494 60 100M = 3121 -472 AAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAA 0ACDFDC9GCF?CGKF:GHLIHJKJIJNJIKIEI2B6FJJJIALHIJKLKHLJKIEJHIH>DGBKJLIIJIIKDIGGLIIALIKHGGHKIJGJHFFDC?E X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@GHIJHF@IDF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ADCDAH ERR242955.586810 99 17 3506 60 100M = 3917 510 ATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACG ?@CCEAEDBDDDEG6GG-IFFCC8FFGEADFHFIHFCAJFDFI9EI6HE>F;BBFGBF4FEAEC>ACEA7?A7 X0:i:1 X1:i:0 MD:Z:81G18 RG:Z:ERR242955 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243031.650799 147 17 3507 60 100M = 3080 -526 TCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGC >GCH1GFFHGHHHFGFGIHHHEEIIIFI;GIAADHIDFFI@HDHAGD>BIAHHIEFBID>FIEFHHFGHDIFFHDEGGEFDEEEFFEJHEGEF@FDD?CA X0:i:1 X1:i:0 MD:Z:80G19 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.8738223 99 17 3511 60 100M = 3914 502 ACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATAAATATACGCAAAC BDDCFBAAIEBIDBGKHE=8DDGGHGHJJDFHHD;LC<=>C=GHKI:?IJB@@H7AHHB0:)J@H(AF:C@HA/378@ X0:i:1 X1:i:0 MD:Z:76G10T12 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR243031.386955 83 17 3511 60 100M = 3144 -466 CCCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAAC $FC@@D>FJJJAFIJIHEJKJHA@GHKHKKHKJCIGJDFHCHFEBJAJHLGEFHGHEIICJEGGJGHFFGGJIIFCIEFCDDEJFDGEGDFDEAFHBAB? X0:i:1 X1:i:0 MD:Z:0A99 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@IB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR243059.116527 99 17 3516 60 100M = 3914 497 TTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTA @@AFCGGDGFJFGEJIFFFFIGHIHHIHGIKIGEDGCGEHAI@EIEEFHCJG@JEJFHHJFHFHGJJEJGIHEGGHHAJGGEGEGDHEH?JDFHE@CDB@ X0:i:1 X1:i:0 MD:Z:71G28 RG:Z:ERR243059 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EEC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.4686821 163 17 3525 60 100M = 3871 445 AGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGT EEEFEJJGHHIJKKLKLLJIHLMJJJJJKJJFLEILHJJIIKKIMHNJJJMKKKJIJJKLJKMKKIKKJKKGHGIIJJIKCKJJIJKJMFCHEIGEEGG< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR242971.1136963 99 17 3535 60 100M = 3893 457 TCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTT ?DDEFFDHGFCI5GFCFDCBGAI@?IF9A>AJHGKD@@ X0:i:1 X1:i:0 MD:Z:52G47 RG:Z:ERR242971 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BE ERR243027.47729 147 17 3547 60 100M = 3134 -512 GATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTC DB?FDE?CAH@FFJGFAGGIEIIGKFIIICKFEGIDJIFJJFFIHE>IHDHFHEDEDCIJFEEJIIIEFHGLDFKCHHGHHIHEBHCHHHFHGGGDFDCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.1106475 163 17 3557 60 108M = 3858 408 CGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTAT ;:CCDDCDCEGHGGFHIEGIDHIIGGFH>IIAFJ?JDEIHHHHH?HHF8HJEK3HBGFADFIKEI;F;HGFEKDGHGHAFGH?FHEH=AGHFIFGHG@JFIGGJGFGE@FEEBAB? X0:i:1 X1:i:0 MD:Z:22G77 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242963.383553 83 17 3565 60 100M = 3234 -430 TCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTAT B>DAB9>7>CD=C@B;@EC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243087 AM:i:18 NM:i:0 SM:i:37 MQ:i:55 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.10508568 83 17 3608 60 100M = 3407 -300 AACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAG >EBGIFGFIJMJBLIIKIJJJJHDJIKKKJJJJJFJJIELIMLLLJJFJDKKKKIJJIIIIHIHJMIMILJIIKHHIGJIHIJLIFJIIHFGJHIIFAED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.12181062 83 17 3613 60 100M = 3434 -278 GTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCA BCFB?IFBLHIHGB7JI=.>EJI8&FKF+IGB7H2JIF7F=?CF5A2+? X0:i:1 X1:i:0 MD:Z:84C15 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR242975.161746 163 17 3623 60 100M = 4004 480 GTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACAC @CGEHDIEIAFEFIEEIFIDFFFI?FIEIJHIEIGBEJEFDCFHGFIDHKHJJJELEBHGHBHGFGHFLGHEFECFHJHEJHFFKGAHDEAHGCIFBFD> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.18994301 83 17 3627 60 100M = 3289 -437 GTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTG ?DEE=HCEFHIHJIJBHJIDGHLLKIFIJCDKJKEIJIIIIHJJFJMELHHKKJLHIHIKIIIILHIJIHIHHLIHIIIKHGGHKHJGGGJFFIFHFGEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.12766080 147 17 3630 60 100M = 3309 -420 TCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCC :==>CF@1DIH4=GCE2L9:8A9EB4/:8JKJHC5CIH3CKE;7EGGE?EDI?=IGEG?IGGG@HFGIHGGFFGHFEIGF6FG6H:CFGAIHJIFAA<=?HBGKGFF8FDHF@?GGIJG9CGHAGH>I.HH?;><;BAFHIHEKHHHAIILFDIHIDGKIGGKFJJLHJJBJFJAHGJKHLJHJADKKIDGDEKL;=DEF;EFFEH>CEGAAKEJFHHHEKEDG?IFGAGJCIHHIGGFHDFIFEHJB>HKDIHHAK=?JEKGKHJHGIGIEH?EHHHIEGGIFF@D=GC@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243039 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR156632.301185 163 17 3655 60 100M = 3885 329 TCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCT BDC@EHFDFFFHGGDGGJJJKKIKFGFIIFHGEHHHJFHHIJGIIILGJIHHMHIJLIKEJIKLKEFJJJLLHLKJIHGLLLKLKDIMFKGIJJHHDD@: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.9849990 163 17 3663 60 100M = 3854 290 ATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAAC EADFFGHGGKJKKLJKIHJJKIJHIJJHMHJJIIHGHKMHMJJIMHKJLIKJJIMMCILIKKLLKLIEHLJMKLKNMK@MJKHLLKLKKIKKJIIHFCDE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR156632.14578469 147 17 3677 60 1S99M = 3384 -391 TAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGTCTCCTGCAACCACAAATCTACTC /.D1G.8'@12H+3IKHF>JJ@';7II::8LK80HME:-)8;I=:,:1BIL0.J;I6EM2'//H4<8>I/70G1.I-005L=JI5@F>>2EE2?@E5A:? X0:i:1 X1:i:0 XC:i:99 MD:Z:75G23 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243079.290863 163 17 3688 37 100M = 4062 473 ATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTG ?BAFCDDCDCEFGGEIEGEIDDGHFGHGFGICHGDEILIGJIHIJCHIHHJMGEKIJEGHGGJHHIIKJJBIHEIHIIJEHGJIAHJLIJHDJFCFGDAE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR016352.12571677 163 17 3692 60 108M = 4043 458 ATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATT :BAA@@BFBGDFGFFHGFDGHDHGEGIG?IEEEIHHHHIHIIHHFHJHIFJDJFGFHIJFIIJEIID8AFEGIEIIIGEIGFJAJ@F=?IK=JH?FBFDFF@;;<@ED X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:23 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR242955.298650 99 17 3708 37 100M = 4076 467 TACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACAC ?ADCFFFDBGHDHGIGHGFJHGFFI?IHHIHGBFJKIGJDGIEKHKGJJJHJFIGHGIHIGFIIGIHJJJEJLHIEFIDJGHGAHFHGGBFCCFH?CAEA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242955 AM:i:0 NM:i:0 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.16735015 99 17 3713 60 100M = 3988 374 CATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCAT B;ICDHEF4BBFH0GJC.:F;MKK.AH6FEL=5IGIFA9GFILF5J8<@G7AH/LI&+>.CDIJF,7K669G;, X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243031.299961 163 17 3714 37 100M = 4080 465 ATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATA ?B@EGCBHEHFEFEHHDGIEIGHHCK@HDBG@IFFD=?BC=E@CEHEH;HHICGHHGIEF>FJIIJAIBIIEGG=DE@<@I;H=HBFIC0F7FF@1DAA: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243047.429920 163 17 3715 37 100M = 4067 451 TTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTAACCTATTCTGGACACGTCATAG @ADEBEFGCGGIJFHFGIGIGHGHHFFJI=?JGFHGGGGGJGGJFHHHDIGDHGDJIDIJJIJKKJ;JHFJ;DGDCEGNHDBDHEJIICGHFF7DAE@5> X0:i:1 X1:i:0 MD:Z:77G22 RG:Z:ERR243047 AM:i:0 NM:i:1 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.12000443 163 17 3721 57 108M = 4045 401 ACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCCTAGAAATAGAGTCCTGC :ADBDCAFGFFGA?IGGAABEBIF=?DBA?AD@B@B?@AB?49B?B??<>?@;B687?96BDB?177)43:@?28B>6963%842;(->,1<3:33?21/24%3,A@0 X0:i:1 X1:i:0 MD:Z:90A17 RG:Z:ERR013140 AM:i:20 NM:i:1 SM:i:37 MQ:i:57 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.3552250 163 17 3731 10 108M = 4051 394 TGTCCCCTCAAGCTTCCCCTCGCTCCTGCAACCACAAATCTACTCTCCGCCTCTCTGGGCTGACCTATTCTCGACACGTTCTAGAAATAGAGTCCTGCCAAACGTCGC /<@70(/>3061&A57-(#.%23.,4>@01B95B>>3:#/&AF@D+B/;%&FCB1+F3@<6B)-,:7%)9'8B<+0D7359F@7@49?@$>/B3(//). MD:Z:20G26T6G4T11G7C0A17A1C4G2 RG:Z:ERR013140 AM:i:10 NM:i:10 SM:i:10 MQ:i:10 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.7468652 99 17 3733 60 100M = 3865 231 TCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACA AECDFHGFFJHIGJJIIJJ0KJKJGKJIIIJHHIGHJKKIKLLLLLLIKKLKKEKEBIHKJFLHIKIKMMHJIJJDHLHIFMIIFJDJIMGIJIIGFDD@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR245049.438880 99 17 3734 60 100M = 4134 499 CCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACAC ?BAEFGFFIHHEJGHFHIDIHHGDGIHGHGEIGHGIKIEJHKHJGIIHDKIJFEA@EEJGHIGEFFKMJG9JFJAGKGCDHDHIGFI?KDFHH?IF?ECD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.10931516 163 17 3750 37 100M = 4074 423 TGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCT @FBCBIJJKJFHFCFJFEDHLIHDMILFJLBLLILI?MHE;J8BFL=CJGFMJMDDK/LKGHJBGDILF) X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:0 NM:i:0 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243075.758288 163 17 3764 60 100M = 4186 521 ACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTT ACECFEHGFHHIIIIJHHIIIJFJJHEEJFHHIFGGKJLHHBGJBGIFGELGHHHEJGLELIJIKIHMGIAELIIIDGJKJFJFKIIIHHDGHIGH=EF@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243075 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ ERR242963.128219 147 17 3766 60 100M = 3359 -506 AAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAG =>AAICDJEJEJHJIKDKHGHHGJBGGCFJHAIHLGGKFJDBHHJDFKJFCGFIILG@JKHIHFDJEAIDJFG@HGGGFGIGKGGHJFFJFIF?JJBBD@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.23480670 73 17 3771 37 108M = 3771 0 TACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCC @?@@DIEHB>GHIJHEBKKFDGGFDKGEEIGCHJGFF=FEKHHGHDFG>FDD?F@DEDGEDKHAIFGCH@EEHGGC>@EC@-G=6D+8(9?F?4B=>E>GAFA@);9# X0:i:1 X1:i:0 MD:Z:107A0 RG:Z:ERR013140 AM:i:0 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.23480670 133 17 3771 0 35M73S = 3771 0 TTCTCATCAATCCCTCATCTCTTATAACCATTTCGGTCCTTTCGGCCCTACAGCCACCTTGTTTATACTTGGTAAGACCCACACCACTCGCCAACTTACTCTACTCCC 8+7?5>09:),/%81,$,7<+?)+1+*+),3%5+)#%(4B%$&'%'/*@,)*%%&,%(/0%-&$$*$-,$3*.%/$:%$+.$*%&+.,.%%,%(%7(-.-',1*6%&$ XC:i:35 RG:Z:ERR013140 ERR162875.18637663 1107 17 3780 60 100M = 3471 -408 CCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAA 0GBCBHDJFC6IKG.?HA?>F:JM8LECJIAEHMHHFIBLK8K=E:6DAIGH:JBFIJJG>MIKKMIIIJKG=E??DC8DCABCGGFDH:BA::<>>8<67=8?>0A X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR013140.22233344 83 17 3784 60 108M = 3490 -401 TGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACA 3:;8-9?=@=;AACF==EEG@H@@?A>DCF=?@ED=@9@CB:=BBJG?FHFLHLHIIHLJIKKIHIH@JIJHKIIGKHJKFJJGIHGJJEIHGIGGDCA@ X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.15409720 83 17 3810 60 100M = 3484 -425 CATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCT CADGGEEIHKKDIIIIIJKBIJIDIGGHJ=JKNJIJJILJIKMIIEFLJEMLJGILIIJLHJJHEBIKGJGJJJIIIIKHKKIHIGJJIGGHIFFHEEGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242975.1167526 163 17 3819 29 100M = 4160 433 AGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTT @EDHEHGIIHHGIEI@GJHHHAFGJKFIFJHIIIIDKJFIG@JIGALJCIJJFKEDEJEHHJJGJIFJHGIHGKFJEFJKEJHJGHGIIIHHDEGFGDEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR013140.9944053 163 17 3821 60 92M16S = 4143 402 AGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCTTTCTTACGGCTG 9AABCCCDEA=EB:CBBD?>EIIEACC;DDE@F@9F0@>45C7:<2=>6CFACE@6@7=50>93&=-48693<@89AA3<*,=A58<44352/%)'/'$%,$$70 X0:i:1 X1:i:0 XC:i:92 MD:Z:92 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.26059461 163 17 3830 57 100M = 4037 306 ACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGA DACBBH7-AG=HJK=FKDIIB9:M1;GJ=DC@IFBBKGHDLH;GHGK:I>J129CJEFJ8G>M=D99A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:20 NM:i:0 SM:i:37 MQ:i:57 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243047.360466 99 17 3832 60 100M = 4185 452 ACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATA @-=CGEEAGEFF;5>CL31D5CC@JHCD/>G26@JGHECFIE7G>BC>GG;III2D@24/'.G>6,90 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243047 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243027.1264030 83 17 3836 29 100M = 3470 -465 GGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCC 9>B=A@=>ABAA@@>9;7>5<=?:29 X0:i:1 X1:i:0 MD:Z:83A24 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.15307937 83 17 3853 29 100M = 3442 -510 TTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTC =>B)IDA7FC8D/DHIF1GJ11J?G=L6DEA>HEE:AGKJ>?AJIJJ4CD;=8HKFIAFDCGBI23EHCLKB5C@JIHG6IDC+BGF>HJ;+IEGGFGDB X0:i:1 X1:i:0 MD:Z:83A16 RG:Z:ERR162875 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR162872.9849990 83 17 3854 60 100M = 3663 -290 TCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCC CHFHG=HKHHJJKBGKIBJICHJLGLLEIMMHKJMIKLKKHIIKKJJJMJJLILMGGKFLIKMJJMGGLKKKMIKJHIGIJCICJJGJJGIIEFHFHE>B X0:i:1 X1:i:0 MD:Z:82A17 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.20934779 83 17 3855 60 100M = 3616 -338 CTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTTTAGCATACACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCT C:>>A6-'07KJDD7D92002-I&K(G2&92/;B98MFH)HB2BCA-E/4KI>.DIG8AIB=HE:C7J+@3KHJB6CDDHDEFGGAABEHDHHIKBFJGKHIJIIJJGKGGK?JFK=B@HDKJHBGJHGKKJKHKHHKIIIJJEGHIKKIJIAIIJKJJIJHIIIJGIIJJIIGGHEDDCA X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.8064738 163 17 3861 37 108M = 4107 353 CTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATA :B@AA@CCBEDDEDDCDFFEGDCDGDDDFCG@EFGEGEGGGFA?@IGFHE@DDHEFIGFIHGHFI7E?GAGHIGBIE9FHEHKDEJF6FBJ=BFC?HIEAH9AGFB5? X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:0 NM:i:0 SM:i:37 MQ:i:8 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.7468652 147 17 3865 60 100M = 3733 -231 GCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCT DF@FJFHGGIDILFLJKHJMIIKKEJKIJHHLKLJKLLIKMEKMIIMJLEGLIIMGIMKLLMGHJIJJHKDJDKLEJMGLMIILIMFKKDHKGGHGEFFD X0:i:1 X1:i:0 MD:Z:71A28 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.9446395 83 17 3871 60 108M = 3647 -331 TGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCAC A8ABBFFFFB=GIHEHIHHJKBH?EKBJCGHJFEFGDHGHJHKGEJHLKKEKFJJKBIIII=KKAIAIJHKJG@JEFJIJEJJHGJFCIBHHJGGHGHDCIHGGHA>D@>AE9>E?: X0:i:1 X1:i:0 MD:Z:61A46 RG:Z:ERR016352 AM:i:20 NM:i:1 SM:i:37 MQ:i:57 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162875.919124 99 17 3879 37 100M = 4109 329 AGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCAC BG@FFFIHGHGGHJHKGHKJIHLLIJJKLKLHKIILIKKHMLHDJKMLKDGIHJILLJBDKJIKIILFAKJDAEH@BKKFF6KIEJK&G8HEB>DB;EDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:0 NM:i:0 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR013140.17460076 163 17 3883 60 108M = 4144 368 CCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCC :DEDDDDCFEBGCFCFE?CBHFJGBDEGGEGFDJJEJHEACGGDEFDA?EBBC1B:@ECDFB@EA>?=E?CAA@F;98@9AECDCA@>=;C@7;=7-2?>A=99.@84 X0:i:1 X1:i:0 MD:Z:53A54 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.301185 83 17 3885 60 100M = 3655 -329 TCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTA :CBGFIIGHIIJKJHKLKFLKJLLHFECKIILKJMFJMLMLMJLKLIIIILHEKKILNJLLEHJGMJLMJJLIJIJKLMKKIHIIIKKGCJJFIKGHGCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR242971.1136963 147 17 3893 60 100M = 3535 -457 TGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTT 0EA=GFDB3FBDEIGJHGGDGHIEBJJDFK72+?./;6-6->D8ABFCCFHAEJEBAGHBEEFCDE=>:@DBHGHAHDEEBCDFDDHJDFHILJLGCHEGDCEFD@JICJHJIHHFHEHJDHDEGCBC6EFDEC@ X0:i:1 X1:i:0 MD:Z:40A60G1G4 RG:Z:ERR013140 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR243087.1477801 83 17 3909 55 100M = 3600 -408 TACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTC 0?F?HBFJGGK:DHHII@FGHDFEEHJFBHJHGKICJ@BKEFGFH@EJGCB:HHJHGGEGFDEJD@HFDGKGIH@FJ?LFA>EHJGDIEEHKEGDBCCB? X0:i:1 X1:i:3 XA:Z:17,-4057,100M,1;17,-4094,100M,1;17,-4168,100M,1; MD:Z:100 RG:Z:ERR243087 AM:i:18 NM:i:0 SM:i:18 MQ:i:55 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR013140.18542909 163 17 3912 60 108M = 4185 380 ACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGC :AEDDD@EGBFIJJIIHIGGGDIJHG;<9+&$&$&-. X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.8738223 147 17 3914 60 100M = 3511 -502 TCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACAC -E8?FIGCF:AKEDCFFH>JADKDDL:9JIHKIIJII>DC@GA3F;GDJHFLIJFEIDLHDLLEKIFMMGGJ>JHLJIIMIEJKKLLGJIHHFHHIEGDB X0:i:1 X1:i:0 MD:Z:22A77 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CAB ERR243059.116527 147 17 3914 60 100M = 3516 -497 TCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACAC =EGADGGDIHHGIGKGGIJGICJCJKGHKIIJFDJFLIHJIGJEFHIHIJLIGFIIFHIDBJJ?EKHKKDFKDKGGKGGIHFJHHIJGJGCFHFCHEGC@ X0:i:1 X1:i:0 MD:Z:22A77 RG:Z:ERR243059 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@@ ERR242955.586810 147 17 3917 60 100M = 3506 -510 TTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACC (C7BB7FG28FJ9E>BAJ3CGHHJEEEDJ>GKGHIHFIEGJCHJHAGGF;IDIBGE>A X0:i:1 X1:i:0 MD:Z:19A80 RG:Z:ERR242955 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR245032.607478 99 17 3950 60 100M = 4200 348 CTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACG ADCDG?GHCDGFJFEG>D@E?@HGDFGHH=EEIHFGFC?GGIIHCIEFED>H>0@CI4(.=FA;,J/.4./BF7?3.@9B7 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR016352.14078817 163 17 3952 60 106M2S = 4187 342 CCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCCCCCGCTAA :?CA@CABDDEDEE>CCEF@DFB'42C;6HBI@9CF8K@6F;E7C>?;D=D6JG?;)>FD:,9HI<.:BIDB0GJHA.3.2IH>HC?0E:@9G+BG82*@B;,BFFFFBB X0:i:1 X1:i:0 MD:Z:69G30 RG:Z:ERR242975 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR013140.11440888 163 17 3974 60 108M = 4283 416 CGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATT :?F>=:+6/@7>>:@2 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR156632.11081426 147 17 3977 60 100M = 3652 -424 CCCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTG #6DGGIHEBALI4LIDKFAIKL1AIDCA@JJ?LIK=I0LG=DBI=LEKI7LHICI:KKJ7;HEHHHCIJKACBIGJIB:JE>J?HHFECGHFFFEFDGFB X0:i:1 X1:i:0 MD:Z:0A99 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR162872.22176921 99 17 3984 37 100M = 4109 224 ACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATTCC BDEEHGGIEIIEGJIHJKKIIHIHKKIJDJIJKKCKLGKIIMKKHHKLHIDMGLJKIJDJEHKKJEKHHK:DKDH8IFJJKBGEIF>IHGBHGFGFE=FC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AB ERR162872.16735015 147 17 3988 60 100M = 3713 -374 TCCTTCTTAGGGCTGATTTGCCACACACCCGCTCCACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGC -6<2;D9H?:AJLDH7?)K0/LH:FF,&3??M4'N2/&0N@J:7;LFJCG7)@HIF=C@ X0:i:1 X1:i:0 MD:Z:17A1T13A66 RG:Z:ERR162872 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR013140.6157908 99 17 3994 37 108M = 4176 276 TTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCC @ABDGGHJGIFGFGIJJFJFKGKK@JKHGKGKJKLIKLHHIJJJLJLHIHIELKHAKLHLLAKLIHLHJKLJIKLDFEIEALIGGFH?DAJC7GHEBEFDIDAD@A<; X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:0 NM:i:0 SM:i:37 MQ:i:23 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ bcftools-1.21/test/mpileup/mpileup.10.out000066400000000000000000000236211467060157400203430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1b HG00100 SAMPLE1a SAMPLE2 SAMPLE3 17 100 . C <*> 0 . DP=16;I16=14,1,0,0,593,24461,0,0,838,48482,0,0,310,7132,0,0;QS=5,0;MQ0F=0 PL 0,3,19 0,6,78 0,12,128 0,9,118 0,15,134 17 101 . C <*> 0 . DP=16;I16=14,1,0,0,567,22633,0,0,838,48482,0,0,309,7011,0,0;QS=5,0;MQ0F=0 PL 0,3,22 0,6,79 0,12,123 0,9,108 0,15,132 17 102 . C <*> 0 . DP=16;I16=14,1,0,0,602,25074,0,0,838,48482,0,0,308,6904,0,0;QS=5,0;MQ0F=0 PL 0,3,20 0,6,78 0,12,129 0,9,121 0,15,139 17 103 . T C,<*> 0 . DP=16;I16=13,1,1,0,588,25334,6,36,809,47641,29,841,301,6775,6,36;QS=4,1,0;SGB=-0.587685;RPBZ=-1.15831;MQBZ=-2.54951;MQSBZ=0.392232;BQBZ=-1.64233;SCBZ=3.74166;MQ0F=0 PL 6,3,0,6,3,6 0,6,79,6,79,79 0,12,131,12,131,131 0,9,118,9,118,118 0,15,147,15,147,147 17 104 . G C,<*> 0 . DP=16;I16=13,1,1,0,536,21966,3,9,809,47641,29,841,298,6634,7,49;QS=4,1,0;SGB=-0.587685;RPBZ=-1.15831;MQBZ=-2.54951;MQSBZ=0.392232;BQBZ=-1.63041;SCBZ=3.74166;MQ0F=0 PL 4,3,0,4,3,4 0,6,78,6,78,78 0,12,123,12,123,123 0,9,101,9,101,101 0,15,133,15,133,133 17 105 . G <*> 0 . DP=17;I16=15,1,0,0,541,20301,0,0,898,52082,0,0,303,6571,0,0;QS=5,0;MQ0F=0 PL 0,6,35 0,6,77 0,12,106 0,9,106 0,15,125 17 106 . G <*> 0 . DP=17;I16=15,1,0,0,562,22318,0,0,898,52082,0,0,302,6476,0,0;QS=5,0;MQ0F=0 PL 0,6,44 0,6,75 0,12,130 0,9,92 0,15,124 17 107 . C <*> 0 . DP=17;I16=15,1,0,0,606,24752,0,0,898,52082,0,0,301,6399,0,0;QS=5,0;MQ0F=0 PL 0,6,36 0,6,77 0,12,130 0,9,119 0,15,136 17 108 . C <*> 0 . DP=17;I16=15,1,0,0,604,24464,0,0,898,52082,0,0,300,6340,0,0;QS=5,0;MQ0F=0 PL 0,6,37 0,6,78 0,12,128 0,9,119 0,15,135 17 109 . T C,<*> 0 . DP=17;I16=14,1,1,0,639,27679,2,4,869,51241,29,841,287,6155,12,144;QS=4.89189,0.108108,0;SGB=-0.587685;RPBZ=-0.759816;MQBZ=-2.64575;MQSBZ=0.377964;BQBZ=-1.6641;SCBZ=2.82843;MQ0F=0 PL 0,1,28,3,31,30 0,6,77,6,77,77 0,12,133,12,133,133 0,9,120,9,120,120 0,15,150,15,150,150 17 110 . G <*> 0 . DP=17;I16=15,1,0,0,608,24834,0,0,898,52082,0,0,298,6276,0,0;QS=5,0;MQ0F=0 PL 0,6,40 0,6,78 0,12,130 0,9,113 0,15,136 17 111 . G <*> 0 . DP=17;I16=15,1,0,0,503,18985,0,0,898,52082,0,0,296,6222,0,0;QS=5,0;MQ0F=0 PL 0,6,45 0,6,75 0,12,92 0,9,95 0,15,119 17 112 . C G,<*> 0 . DP=17;I16=14,1,1,0,577,23365,2,4,869,51241,29,841,279,5963,15,225;QS=4.88235,0.117647,0;SGB=-0.587685;RPBZ=-0.542725;MQBZ=-2.64575;MQSBZ=0.377964;BQBZ=-1.63663;SCBZ=2.82843;MQ0F=0 PL 0,1,25,3,28,27 0,6,77,6,77,77 0,12,129,12,129,129 0,9,103,9,103,103 0,15,135,15,135,135 17 113 . A G,<*> 0 . DP=17;I16=14,1,1,0,565,22603,4,16,869,51241,29,841,275,5867,16,256;QS=4.88235,0.117647,0;SGB=-0.587685;RPBZ=-0.542725;MQBZ=-2.64575;MQSBZ=0.377964;BQBZ=-1.64646;SCBZ=2.82843;MQ0F=0 PL 0,1,25,3,28,27 0,6,71,6,71,71 0,12,120,12,120,120 0,9,102,9,102,102 0,15,139,15,139,139 17 114 . C <*> 0 . DP=17;I16=15,1,0,0,581,22755,0,0,898,52082,0,0,288,6076,0,0;QS=5,0;MQ0F=0 PL 0,6,38 0,6,75 0,12,118 0,9,113 0,15,133 17 115 . C A,<*> 0 . DP=19;I16=15,2,1,0,615,24761,12,144,958,55682,29,841,261,5423,25,625;QS=4.88785,0.11215,0;SGB=-0.587685;RPBZ=0.28942;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.4501;SCBZ=-0.445021;MQ0F=0 PL 0,6,43,6,43,43 0,6,80,6,80,80 0,12,123,12,123,123 3,0,86,9,89,93 0,21,153,21,153,153 17 116 . A C,<*> 0 . DP=19;I16=15,2,1,0,631,25045,2,4,958,55682,29,841,265,5631,19,361;QS=4.90244,0.097561,0;SGB=-0.587685;RPBZ=0.0964735;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.65205;SCBZ=2.52179;MQ0F=0 PL 0,1,32,3,35,34 0,6,75,6,75,75 0,12,121,12,121,121 0,9,102,9,102,102 0,21,175,21,175,175 17 117 . G <*> 0 . DP=19;I16=16,2,0,0,635,24843,0,0,987,56523,0,0,282,5960,0,0;QS=5,0;MQ0F=0 PL 0,6,42 0,6,77 0,12,117 0,9,97 0,21,177 17 118 . G <*> 0 . DP=19;I16=16,2,0,0,583,22101,0,0,987,56523,0,0,280,5952,0,0;QS=5,0;MQ0F=0 PL 0,6,43 0,6,77 0,12,116 0,9,65 0,21,162 17 119 . G <*> 0 . DP=18;I16=15,2,0,0,581,22015,0,0,927,52923,0,0,277,5917,0,0;QS=5,0;MQ0F=0 PL 0,6,47 0,6,78 0,12,114 0,6,76 0,21,160 17 120 . A G,<*> 0 . DP=18;I16=14,2,1,0,608,23948,4,16,898,52082,29,841,252,5374,23,529;QS=4.91111,0.0888889,0;SGB=-0.587685;RPBZ=0.204375;MQBZ=-2.16025;MQSBZ=-1.23956;BQBZ=-1.64411;SCBZ=2.91548;MQ0F=0 PL 0,1,36,3,39,38 0,6,75,6,75,75 0,12,116,12,116,116 0,6,88,6,88,88 0,21,171,21,171,171 17 121 . G <*> 0 . DP=18;I16=15,2,0,0,619,24187,0,0,927,52923,0,0,273,5909,0,0;QS=5,0;MQ0F=0 PL 0,6,48 0,6,80 0,12,121 0,6,84 0,21,168 17 122 . C <*> 0 . DP=19;I16=16,2,0,0,655,26103,0,0,987,56523,0,0,271,5935,0,0;QS=5,0;MQ0F=0 PL 0,6,42 0,6,78 0,12,119 0,9,107 0,21,178 17 123 . T <*> 0 . DP=17;I16=14,2,0,0,610,24776,0,0,867,49323,0,0,271,5929,0,0;QS=5,0;MQ0F=0 PL 0,6,48 0,6,75 0,9,99 0,9,123 0,18,166 17 124 . T <*> 0 . DP=17;I16=14,2,0,0,547,20261,0,0,867,49323,0,0,271,5939,0,0;QS=5,0;MQ0F=0 PL 0,6,33 0,6,70 0,9,89 0,9,114 0,18,154 17 125 . A T,<*> 0 . DP=16;I16=12,2,1,0,522,20316,4,16,778,44882,29,841,246,5290,25,625;QS=4.90476,0.0952381,0;SGB=-0.587685;RPBZ=0.926648;MQBZ=-2;MQSBZ=-1.1007;BQBZ=-1.62747;SCBZ=2.73861;MQ0F=0 PL 0,1,33,3,36,35 0,6,72,6,72,72 0,6,63,6,63,63 0,9,114,9,114,114 0,18,162,18,162,162 17 126 . A <*> 0 . DP=16;I16=13,2,0,0,558,22192,0,0,807,45723,0,0,271,5907,0,0;QS=5,0;MQ0F=0 PL 0,6,50 0,6,72 0,6,67 0,9,117 0,18,174 17 127 . C <*> 0 . DP=16;I16=13,2,0,0,554,21662,0,0,807,45723,0,0,271,5915,0,0;QS=5,0;MQ0F=0 PL 0,6,46 0,6,69 0,6,75 0,9,119 0,18,160 17 128 . A <*> 0 . DP=16;I16=13,2,0,0,588,23772,0,0,807,45723,0,0,271,5939,0,0;QS=5,0;MQ0F=0 PL 0,6,59 0,6,74 0,6,72 0,9,121 0,18,168 17 129 . A <*> 0 . DP=15;I16=12,2,0,0,558,23026,0,0,747,42123,0,0,272,5978,0,0;QS=5,0;MQ0F=0 PL 0,6,59 0,6,72 0,6,73 0,9,124 0,15,159 17 130 . A <*> 0 . DP=15;I16=12,2,0,0,556,22898,0,0,747,42123,0,0,273,6031,0,0;QS=5,0;MQ0F=0 PL 0,6,60 0,6,76 0,6,68 0,9,124 0,15,152 17 131 . C <*> 0 . DP=14;I16=11,2,0,0,517,21115,0,0,718,41282,0,0,248,5422,0,0;QS=5,0;MQ0F=0 PL 0,3,38 0,6,77 0,6,71 0,9,120 0,15,147 17 132 . A <*> 0 . DP=14;I16=11,2,0,0,535,22437,0,0,718,41282,0,0,248,5450,0,0;QS=5,0;MQ0F=0 PL 0,3,42 0,6,73 0,6,75 0,9,120 0,15,151 17 133 . T <*> 0 . DP=13;I16=11,2,0,0,512,20224,0,0,718,41282,0,0,248,5490,0,0;QS=5,0;MQ0F=0 PL 0,3,38 0,6,74 0,6,71 0,9,105 0,15,150 17 134 . C <*> 0 . DP=13;I16=11,2,0,0,526,21368,0,0,718,41282,0,0,248,5542,0,0;QS=5,0;MQ0F=0 PL 0,3,41 0,6,79 0,6,77 0,9,105 0,15,152 17 135 . T <*> 0 . DP=13;I16=11,2,0,0,528,21588,0,0,718,41282,0,0,248,5606,0,0;QS=5,0;MQ0F=0 PL 0,3,40 0,6,78 0,6,77 0,9,106 0,15,159 17 136 . G <*> 0 . DP=13;I16=11,2,0,0,495,19137,0,0,718,41282,0,0,249,5681,0,0;QS=5,0;MQ0F=0 PL 0,3,39 0,6,79 0,6,71 0,9,105 0,15,134 17 137 . T <*> 0 . DP=13;I16=11,2,0,0,494,18984,0,0,718,41282,0,0,251,5767,0,0;QS=5,0;MQ0F=0 PL 0,3,39 0,6,73 0,6,69 0,9,104 0,15,139 17 138 . C <*> 0 . DP=13;I16=11,2,0,0,504,19886,0,0,718,41282,0,0,252,5816,0,0;QS=5,0;MQ0F=0 PL 0,3,40 0,6,79 0,6,71 0,9,108 0,15,142 17 139 . C <*> 0 . DP=13;I16=11,2,0,0,479,17977,0,0,718,41282,0,0,252,5830,0,0;QS=5,0;MQ0F=0 PL 0,3,37 0,6,76 0,6,62 0,9,106 0,15,143 17 140 . A <*> 0 . DP=13;I16=11,2,0,0,509,20051,0,0,718,41282,0,0,251,5809,0,0;QS=5,0;MQ0F=0 PL 0,3,39 0,6,73 0,6,70 0,9,107 0,15,153 17 141 . G <*> 0 . DP=12;I16=10,2,0,0,452,17388,0,0,658,37682,0,0,250,5750,0,0;QS=5,0;MQ0F=0 PL 0,3,36 0,6,79 0,3,34 0,9,108 0,15,142 17 142 . C <*> 0 . DP=12;I16=10,2,0,0,426,15624,0,0,658,37682,0,0,249,5701,0,0;QS=5,0;MQ0F=0 PL 0,3,39 0,6,78 0,3,37 0,9,97 0,15,129 17 143 . G <*> 0 . DP=12;I16=10,2,0,0,364,11856,0,0,658,37682,0,0,248,5662,0,0;QS=5,0;MQ0F=0 PL 0,3,33 0,6,60 0,3,36 0,9,95 0,15,102 17 144 . A <*> 0 . DP=12;I16=10,2,0,0,443,16837,0,0,658,37682,0,0,246,5584,0,0;QS=5,0;MQ0F=0 PL 0,3,33 0,6,75 0,3,41 0,9,105 0,15,129 17 145 . A <*> 0 . DP=12;I16=10,2,0,0,451,17401,0,0,658,37682,0,0,244,5518,0,0;QS=5,0;MQ0F=0 PL 0,3,42 0,6,74 0,3,34 0,9,106 0,15,138 17 146 . T <*> 0 . DP=12;I16=10,2,0,0,439,16671,0,0,658,37682,0,0,242,5464,0,0;QS=5,0;MQ0F=0 PL 0,3,37 0,6,73 0,3,41 0,9,103 0,15,128 17 147 . A <*> 0 . DP=12;I16=10,2,0,0,444,16692,0,0,658,37682,0,0,240,5422,0,0;QS=5,0;MQ0F=0 PL 0,3,40 0,6,70 0,3,41 0,9,99 0,15,140 17 148 . C <*> 0 . DP=12;I16=10,2,0,0,465,18131,0,0,658,37682,0,0,237,5341,0,0;QS=5,0;MQ0F=0 PL 0,3,39 0,6,77 0,3,41 0,9,106 0,15,146 17 149 . C <*> 0 . DP=12;I16=10,2,0,0,433,16205,0,0,658,37682,0,0,233,5221,0,0;QS=5,0;MQ0F=0 PL 0,3,38 0,6,77 0,3,18 0,9,109 0,15,140 17 150 . T <*> 0 . DP=11;I16=9,2,0,0,436,17434,0,0,629,36841,0,0,230,5112,0,0;QS=5,0;MQ0F=0 PL 0,3,36 0,6,76 0,3,40 0,6,84 0,15,152 bcftools-1.21/test/mpileup/mpileup.11.out000066400000000000000000014610211467060157400203450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00102 17 1 . A <*> 0 . DP=3;I16=3,0,0,0,124,5126,0,0,87,2523,0,0,41,625,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 2 . A <*> 0 . DP=3;I16=3,0,0,0,120,4800,0,0,87,2523,0,0,42,630,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 3 . G <*> 0 . DP=3;I16=3,0,0,0,118,4642,0,0,87,2523,0,0,43,641,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 4 . C <*> 0 . DP=3;I16=3,0,0,0,106,3828,0,0,87,2523,0,0,44,658,0,0;QS=1,0;MQ0F=0 PL 0,9,71 17 5 . T <*> 0 . DP=3;I16=3,0,0,0,116,4534,0,0,87,2523,0,0,45,681,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 6 . T <*> 0 . DP=3;I16=3,0,0,0,116,4490,0,0,87,2523,0,0,46,710,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 7 . C <*> 0 . DP=3;I16=3,0,0,0,118,4660,0,0,87,2523,0,0,47,745,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 8 . T <*> 0 . DP=3;I16=3,0,0,0,125,5213,0,0,87,2523,0,0,48,786,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 9 . C <*> 0 . DP=3;I16=3,0,0,0,123,5045,0,0,87,2523,0,0,49,833,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 10 . A <*> 0 . DP=3;I16=3,0,0,0,104,3746,0,0,87,2523,0,0,50,886,0,0;QS=1,0;MQ0F=0 PL 0,9,69 17 11 . C <*> 0 . DP=3;I16=3,0,0,0,113,4269,0,0,87,2523,0,0,51,945,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 12 . C <*> 0 . DP=3;I16=3,0,0,0,120,4826,0,0,87,2523,0,0,52,1010,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 13 . C <*> 0 . DP=3;I16=3,0,0,0,112,4226,0,0,87,2523,0,0,53,1081,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 14 . T <*> 0 . DP=3;I16=3,0,0,0,121,4925,0,0,87,2523,0,0,54,1158,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 15 . G <*> 0 . DP=3;I16=3,0,0,0,115,4453,0,0,87,2523,0,0,54,1190,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 16 . T <*> 0 . DP=3;I16=3,0,0,0,120,4802,0,0,87,2523,0,0,54,1226,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 17 . T <*> 0 . DP=3;I16=3,0,0,0,110,4122,0,0,87,2523,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 18 . C <*> 0 . DP=3;I16=3,0,0,0,117,4605,0,0,87,2523,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 19 . C <*> 0 . DP=3;I16=3,0,0,0,121,4899,0,0,87,2523,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 20 . T <*> 0 . DP=3;I16=3,0,0,0,126,5300,0,0,87,2523,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 21 . G <*> 0 . DP=3;I16=3,0,0,0,115,4417,0,0,87,2523,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 22 . C <*> 0 . DP=3;I16=3,0,0,0,115,4459,0,0,118,5282,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,76 17 23 . A <*> 0 . DP=3;I16=3,0,0,0,120,4802,0,0,118,5282,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,82 17 24 . T <*> 0 . DP=3;I16=3,0,0,0,118,4650,0,0,118,5282,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 25 . A <*> 0 . DP=3;I16=3,0,0,0,119,4725,0,0,118,5282,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,81 17 26 . G <*> 0 . DP=3;I16=3,0,0,0,123,5061,0,0,118,5282,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,81 17 27 . A <*> 0 . DP=3;I16=3,0,0,0,125,5213,0,0,118,5282,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,83 17 28 . T <*> 0 . DP=4;I16=4,0,0,0,153,5891,0,0,178,8882,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,12,101 17 29 . A <*> 0 . DP=4;I16=4,0,0,0,151,5727,0,0,178,8882,0,0,58,1300,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 30 . A <*> 0 . DP=4;I16=4,0,0,0,167,6991,0,0,178,8882,0,0,60,1318,0,0;QS=1,0;MQ0F=0 PL 0,12,108 17 31 . T <*> 0 . DP=4;I16=4,0,0,0,158,6250,0,0,178,8882,0,0,62,1340,0,0;QS=1,0;MQ0F=0 PL 0,12,105 17 32 . T <*> 0 . DP=4;I16=4,0,0,0,155,6033,0,0,178,8882,0,0,64,1366,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 33 . G <*> 0 . DP=4;I16=4,0,0,0,151,5775,0,0,178,8882,0,0,66,1396,0,0;QS=1,0;MQ0F=0 PL 0,12,105 17 34 . C <*> 0 . DP=4;I16=4,0,0,0,150,5786,0,0,178,8882,0,0,68,1430,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 35 . A <*> 0 . DP=5;I16=5,0,0,0,192,7416,0,0,238,12482,0,0,70,1468,0,0;QS=1,0;MQ0F=0 PL 0,15,121 17 36 . T <*> 0 . DP=5;I16=5,0,0,0,197,7781,0,0,238,12482,0,0,73,1511,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 37 . G <*> 0 . DP=5;I16=5,0,0,0,198,7852,0,0,238,12482,0,0,76,1560,0,0;QS=1,0;MQ0F=0 PL 0,15,126 17 38 . A <*> 0 . DP=5;I16=5,0,0,0,205,8419,0,0,238,12482,0,0,79,1615,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 39 . C <*> 0 . DP=5;I16=5,0,0,0,188,7106,0,0,238,12482,0,0,82,1676,0,0;QS=1,0;MQ0F=0 PL 0,15,123 17 40 . A <*> 0 . DP=5;I16=5,0,0,0,202,8166,0,0,238,12482,0,0,85,1743,0,0;QS=1,0;MQ0F=0 PL 0,15,127 17 41 . A <*> 0 . DP=5;I16=5,0,0,0,211,8925,0,0,238,12482,0,0,88,1816,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 42 . T <*> 0 . DP=5;I16=5,0,0,0,201,8087,0,0,238,12482,0,0,91,1895,0,0;QS=1,0;MQ0F=0 PL 0,15,127 17 43 . T <*> 0 . DP=5;I16=5,0,0,0,206,8496,0,0,238,12482,0,0,94,1980,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 44 . G <*> 0 . DP=5;I16=5,0,0,0,200,8014,0,0,238,12482,0,0,97,2071,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 45 . C <*> 0 . DP=5;I16=5,0,0,0,196,7690,0,0,238,12482,0,0,100,2168,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 46 . C <*> 0 . DP=5;I16=5,0,0,0,206,8506,0,0,238,12482,0,0,103,2271,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 47 . T <*> 0 . DP=5;I16=5,0,0,0,218,9510,0,0,238,12482,0,0,106,2380,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 48 . T <*> 0 . DP=5;I16=5,0,0,0,207,8573,0,0,238,12482,0,0,108,2444,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 49 . G <*> 0 . DP=5;I16=5,0,0,0,195,7663,0,0,238,12482,0,0,110,2512,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 50 . T <*> 0 . DP=5;I16=5,0,0,0,200,8008,0,0,238,12482,0,0,112,2584,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 51 . C <*> 0 . DP=5;I16=5,0,0,0,202,8218,0,0,238,12482,0,0,114,2660,0,0;QS=1,0;MQ0F=0 PL 0,15,127 17 52 . C <*> 0 . DP=5;I16=5,0,0,0,191,7441,0,0,238,12482,0,0,116,2740,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 53 . C <*> 0 . DP=5;I16=5,0,0,0,199,7965,0,0,238,12482,0,0,118,2824,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 54 . T <*> 0 . DP=5;I16=5,0,0,0,212,9018,0,0,238,12482,0,0,119,2861,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 55 . G <*> 0 . DP=5;I16=5,0,0,0,191,7351,0,0,238,12482,0,0,120,2900,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 56 . C <*> 0 . DP=5;I16=5,0,0,0,208,8666,0,0,238,12482,0,0,121,2941,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 57 . T <*> 0 . DP=5;I16=5,0,0,0,220,9682,0,0,238,12482,0,0,122,2984,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 58 . G <*> 0 . DP=5;I16=5,0,0,0,209,8743,0,0,238,12482,0,0,123,3029,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 59 . A <*> 0 . DP=5;I16=5,0,0,0,213,9079,0,0,238,12482,0,0,124,3076,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 60 . A <*> 0 . DP=5;I16=5,0,0,0,220,9682,0,0,238,12482,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 61 . T <*> 0 . DP=5;I16=5,0,0,0,207,8573,0,0,238,12482,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 62 . G <*> 0 . DP=6;I16=6,0,0,0,235,9285,0,0,298,16082,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,18,141 17 63 . T <*> 0 . DP=6;I16=6,0,0,0,239,9549,0,0,298,16082,0,0,126,3126,0,0;QS=1,0;MQ0F=0 PL 0,18,144 17 64 . G <*> 0 . DP=6;I16=6,0,0,0,239,9567,0,0,298,16082,0,0,127,3129,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 65 . C <*> 0 . DP=6;I16=6,0,0,0,245,10053,0,0,298,16082,0,0,127,3085,0,0;QS=1,0;MQ0F=0 PL 0,18,147 17 66 . T <*> 0 . DP=6;I16=6,0,0,0,257,11029,0,0,298,16082,0,0,127,3045,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 67 . C <*> 0 . DP=6;I16=6,0,0,0,244,9978,0,0,298,16082,0,0,127,3009,0,0;QS=1,0;MQ0F=0 PL 0,18,147 17 68 . T <*> 0 . DP=6;I16=6,0,0,0,253,10703,0,0,298,16082,0,0,126,2928,0,0;QS=1,0;MQ0F=0 PL 0,18,151 17 69 . G <*> 0 . DP=6;I16=6,0,0,0,238,9500,0,0,298,16082,0,0,125,2853,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 70 . G <*> 0 . DP=6;I16=6,0,0,0,219,8153,0,0,298,16082,0,0,124,2784,0,0;QS=1,0;MQ0F=0 PL 0,18,141 17 71 . G <*> 0 . DP=6;I16=6,0,0,0,201,7413,0,0,298,16082,0,0,123,2721,0,0;QS=1,0;MQ0F=0 PL 0,18,133 17 72 . G <*> 0 . DP=6;I16=6,0,0,0,202,7534,0,0,298,16082,0,0,122,2664,0,0;QS=1,0;MQ0F=0 PL 0,18,133 17 73 . T <*> 0 . DP=6;I16=6,0,0,0,234,9136,0,0,298,16082,0,0,121,2613,0,0;QS=1,0;MQ0F=0 PL 0,18,143 17 74 . C <*> 0 . DP=6;I16=6,0,0,0,226,8538,0,0,298,16082,0,0,120,2568,0,0;QS=1,0;MQ0F=0 PL 0,18,141 17 75 . T <*> 0 . DP=6;I16=6,0,0,0,254,10820,0,0,298,16082,0,0,119,2529,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 76 . C <*> 0 . DP=6;I16=6,0,0,0,245,10019,0,0,298,16082,0,0,118,2496,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 77 . T <*> 0 . DP=6;I16=6,0,0,0,260,11324,0,0,298,16082,0,0,117,2469,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 78 . G <*> 0 . DP=6;I16=6,0,0,0,244,9950,0,0,298,16082,0,0,116,2448,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 79 . G <*> 0 . DP=6;I16=6,0,0,0,239,9559,0,0,298,16082,0,0,115,2433,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 80 . G <*> 0 . DP=6;I16=6,0,0,0,239,9629,0,0,298,16082,0,0,114,2424,0,0;QS=1,0;MQ0F=0 PL 0,18,151 17 81 . G <*> 0 . DP=6;I16=6,0,0,0,228,8810,0,0,298,16082,0,0,113,2421,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 82 . T <*> 0 . DP=6;I16=6,0,0,0,211,7515,0,0,298,16082,0,0,112,2424,0,0;QS=1,0;MQ0F=0 PL 0,18,131 17 83 . C <*> 0 . DP=6;I16=6,0,0,0,237,9371,0,0,298,16082,0,0,111,2433,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 84 . T <*> 0 . DP=6;I16=6,0,0,0,256,10966,0,0,298,16082,0,0,110,2448,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 85 . C <*> 0 . DP=6;I16=6,0,0,0,242,9858,0,0,298,16082,0,0,109,2469,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 86 . A <*> 0 . DP=6;I16=6,0,0,0,246,10098,0,0,298,16082,0,0,108,2496,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 87 . C <*> 0 . DP=6;I16=6,0,0,0,236,9318,0,0,298,16082,0,0,107,2529,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 88 . C <*> 0 . DP=6;I16=6,0,0,0,240,9678,0,0,298,16082,0,0,105,2517,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 89 . C <*> 0 . DP=6;I16=6,0,0,0,243,9901,0,0,298,16082,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 90 . A <*> 0 . DP=5;I16=5,0,0,0,200,8026,0,0,269,15241,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 91 . C <*> 0 . DP=5;I16=5,0,0,0,186,7048,0,0,269,15241,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 92 . G <*> 0 . DP=5;I16=5,0,0,0,133,3673,0,0,269,15241,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,96 17 93 . A <*> 0 . DP=5;I16=5,0,0,0,203,8339,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 94 . C <*> 0 . DP=5;I16=5,0,0,0,189,7181,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 95 . C <*> 0 . DP=5;I16=5,0,0,0,188,7166,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 96 . A <*> 0 . DP=5;I16=5,0,0,0,188,7130,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 97 . A <*> 0 . DP=5;I16=5,0,0,0,204,8350,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 98 . C <*> 0 . DP=5;I16=5,0,0,0,186,6926,0,0,300,18000,0,0,104,2476,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 99 . T <*> 0 . DP=5;I16=5,0,0,0,216,9340,0,0,300,18000,0,0,104,2440,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 100 . C <*> 0 . DP=5;I16=5,0,0,0,188,7146,0,0,300,18000,0,0,104,2408,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 101 . C <*> 0 . DP=5;I16=5,0,0,0,187,7005,0,0,300,18000,0,0,104,2380,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 102 . C <*> 0 . DP=5;I16=5,0,0,0,197,7767,0,0,300,18000,0,0,104,2356,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 103 . T <*> 0 . DP=5;I16=5,0,0,0,207,8593,0,0,300,18000,0,0,104,2336,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 104 . G <*> 0 . DP=5;I16=5,0,0,0,187,7033,0,0,300,18000,0,0,103,2271,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 105 . G <*> 0 . DP=5;I16=5,0,0,0,176,6234,0,0,300,18000,0,0,102,2212,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 106 . G <*> 0 . DP=5;I16=5,0,0,0,170,6050,0,0,300,18000,0,0,101,2159,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 107 . C <*> 0 . DP=5;I16=5,0,0,0,190,7310,0,0,300,18000,0,0,100,2112,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 108 . C <*> 0 . DP=5;I16=5,0,0,0,190,7266,0,0,300,18000,0,0,99,2071,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 109 . T <*> 0 . DP=5;I16=5,0,0,0,212,8996,0,0,300,18000,0,0,98,2036,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 110 . G <*> 0 . DP=5;I16=5,0,0,0,192,7394,0,0,300,18000,0,0,97,2007,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 111 . G <*> 0 . DP=5;I16=5,0,0,0,159,5921,0,0,300,18000,0,0,95,1935,0,0;QS=1,0;MQ0F=0 PL 0,15,119 17 112 . C <*> 0 . DP=5;I16=5,0,0,0,188,7158,0,0,300,18000,0,0,93,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 113 . A <*> 0 . DP=5;I16=5,0,0,0,196,7732,0,0,300,18000,0,0,91,1815,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 114 . C <*> 0 . DP=5;I16=5,0,0,0,188,7086,0,0,300,18000,0,0,89,1767,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 115 . C <*> 0 . DP=7;I16=6,1,0,0,226,8436,0,0,389,22441,0,0,88,1728,0,0;QS=1,0;MQ0F=0 PL 0,21,153 17 116 . A <*> 0 . DP=7;I16=6,1,0,0,249,9091,0,0,389,22441,0,0,88,1700,0,0;QS=1,0;MQ0F=0 PL 0,21,175 17 117 . G <*> 0 . DP=7;I16=6,1,0,0,256,9462,0,0,389,22441,0,0,88,1684,0,0;QS=1,0;MQ0F=0 PL 0,21,177 17 118 . G <*> 0 . DP=7;I16=6,1,0,0,237,8065,0,0,389,22441,0,0,88,1680,0,0;QS=1,0;MQ0F=0 PL 0,21,162 17 119 . G <*> 0 . DP=7;I16=6,1,0,0,223,7487,0,0,389,22441,0,0,87,1637,0,0;QS=1,0;MQ0F=0 PL 0,21,160 17 120 . A <*> 0 . DP=7;I16=6,1,0,0,247,8873,0,0,389,22441,0,0,86,1604,0,0;QS=1,0;MQ0F=0 PL 0,21,171 17 121 . G <*> 0 . DP=7;I16=6,1,0,0,239,8281,0,0,389,22441,0,0,85,1581,0,0;QS=1,0;MQ0F=0 PL 0,21,168 17 122 . C <*> 0 . DP=7;I16=6,1,0,0,261,9859,0,0,389,22441,0,0,84,1568,0,0;QS=1,0;MQ0F=0 PL 0,21,178 17 123 . T <*> 0 . DP=6;I16=5,1,0,0,230,9030,0,0,329,18841,0,0,84,1564,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 124 . T <*> 0 . DP=6;I16=5,1,0,0,212,7558,0,0,329,18841,0,0,84,1568,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 125 . A <*> 0 . DP=6;I16=5,1,0,0,218,7960,0,0,329,18841,0,0,84,1580,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 126 . A <*> 0 . DP=6;I16=5,1,0,0,233,9117,0,0,329,18841,0,0,84,1600,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 127 . C <*> 0 . DP=6;I16=5,1,0,0,220,8134,0,0,329,18841,0,0,84,1628,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 128 . A <*> 0 . DP=6;I16=5,1,0,0,230,8828,0,0,329,18841,0,0,84,1664,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 129 . A <*> 0 . DP=5;I16=4,1,0,0,201,8125,0,0,269,15241,0,0,85,1707,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 130 . A <*> 0 . DP=5;I16=4,1,0,0,195,7685,0,0,269,15241,0,0,86,1756,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 131 . C <*> 0 . DP=5;I16=4,1,0,0,186,6968,0,0,269,15241,0,0,87,1811,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 132 . A <*> 0 . DP=5;I16=4,1,0,0,194,7534,0,0,269,15241,0,0,88,1872,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 133 . T <*> 0 . DP=5;I16=4,1,0,0,197,7785,0,0,269,15241,0,0,89,1939,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 134 . C <*> 0 . DP=5;I16=4,1,0,0,192,7410,0,0,269,15241,0,0,90,2012,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 135 . T <*> 0 . DP=5;I16=4,1,0,0,197,7879,0,0,269,15241,0,0,91,2091,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 136 . G <*> 0 . DP=5;I16=4,1,0,0,170,5902,0,0,269,15241,0,0,93,2175,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 137 . T <*> 0 . DP=5;I16=4,1,0,0,179,6559,0,0,269,15241,0,0,96,2264,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 138 . C <*> 0 . DP=5;I16=4,1,0,0,175,6329,0,0,269,15241,0,0,98,2310,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 139 . C <*> 0 . DP=5;I16=4,1,0,0,174,6232,0,0,269,15241,0,0,100,2364,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 140 . A <*> 0 . DP=5;I16=4,1,0,0,192,7430,0,0,269,15241,0,0,101,2375,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 141 . G <*> 0 . DP=5;I16=4,1,0,0,175,6313,0,0,269,15241,0,0,101,2341,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 142 . C <*> 0 . DP=5;I16=4,1,0,0,156,5110,0,0,269,15241,0,0,101,2311,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 143 . G <*> 0 . DP=5;I16=4,1,0,0,129,3813,0,0,269,15241,0,0,101,2285,0,0;QS=1,0;MQ0F=0 PL 0,15,102 17 144 . A <*> 0 . DP=5;I16=4,1,0,0,167,5899,0,0,269,15241,0,0,101,2263,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 145 . A <*> 0 . DP=5;I16=4,1,0,0,176,6526,0,0,269,15241,0,0,101,2245,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 146 . T <*> 0 . DP=5;I16=4,1,0,0,163,5775,0,0,269,15241,0,0,101,2231,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 147 . A <*> 0 . DP=5;I16=4,1,0,0,173,6177,0,0,269,15241,0,0,101,2221,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 148 . C <*> 0 . DP=5;I16=4,1,0,0,183,6731,0,0,269,15241,0,0,101,2215,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 149 . C <*> 0 . DP=5;I16=4,1,0,0,177,6309,0,0,269,15241,0,0,101,2213,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 150 . T <*> 0 . DP=5;I16=4,1,0,0,193,7557,0,0,269,15241,0,0,101,2215,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 151 . G <*> 0 . DP=5;I16=4,1,0,0,182,6682,0,0,269,15241,0,0,101,2221,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 152 . C <*> 0 . DP=5;I16=4,1,0,0,187,7013,0,0,269,15241,0,0,101,2231,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 153 . A <*> 0 . DP=5;I16=4,1,0,0,197,7771,0,0,269,15241,0,0,101,2245,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 154 . T <*> 0 . DP=5;I16=4,1,0,0,179,6805,0,0,269,15241,0,0,101,2263,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 155 . C <*> 0 . DP=5;I16=4,1,0,0,174,6156,0,0,269,15241,0,0,101,2285,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 156 . C <*> 0 . DP=5;I16=4,1,0,0,190,7238,0,0,269,15241,0,0,101,2311,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 157 . C <*> 0 . DP=5;I16=4,1,0,0,192,7384,0,0,269,15241,0,0,101,2341,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 158 . T <*> 0 . DP=5;I16=4,1,0,0,205,8455,0,0,269,15241,0,0,101,2375,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 159 . A G,<*> 0 . DP=6;I16=4,1,1,0,179,6513,5,25,269,15241,60,3600,101,2413,0,0;QS=0.97076,0.0292398,0;SGB=-0.379885;RPBZ=-1.46385;MQBZ=0.447214;MQSBZ=-2.23607;BQBZ=-1.46385;SCBZ=0;MQ0F=0 PL 0,10,129,15,132,129 17 160 . G <*> 0 . DP=6;I16=5,1,0,0,187,6199,0,0,329,18841,0,0,102,2456,0,0;QS=1,0;MQ0F=0 PL 0,18,139 17 161 . A <*> 0 . DP=6;I16=5,1,0,0,225,8479,0,0,329,18841,0,0,103,2505,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 162 . A <*> 0 . DP=6;I16=5,1,0,0,233,9149,0,0,329,18841,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 163 . G <*> 0 . DP=5;I16=4,1,0,0,175,6497,0,0,269,15241,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 164 . T <*> 0 . DP=6;I16=5,1,0,0,184,6260,0,0,329,18841,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,18,136 17 165 . G <*> 0 . DP=6;I16=5,1,0,0,167,5795,0,0,329,18841,0,0,107,2537,0,0;QS=1,0;MQ0F=0 PL 0,18,127 17 166 . A <*> 0 . DP=6;I16=5,1,0,0,200,7684,0,0,329,18841,0,0,109,2553,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 167 . A <*> 0 . DP=6;I16=5,1,0,0,201,7495,0,0,329,18841,0,0,111,2573,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 168 . G <*> 0 . DP=6;I16=5,1,0,0,186,6590,0,0,329,18841,0,0,113,2597,0,0;QS=1,0;MQ0F=0 PL 0,18,140 17 169 . C <*> 0 . DP=6;I16=5,1,0,0,191,6931,0,0,329,18841,0,0,114,2576,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 170 . C <*> 0 . DP=6;I16=5,1,0,0,193,6731,0,0,329,18841,0,0,115,2561,0,0;QS=1,0;MQ0F=0 PL 0,18,143 17 171 . A <*> 0 . DP=6;I16=5,1,0,0,229,8851,0,0,329,18841,0,0,116,2552,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 172 . C <*> 0 . DP=6;I16=5,1,0,0,181,6059,0,0,329,18841,0,0,117,2549,0,0;QS=1,0;MQ0F=0 PL 0,18,133 17 173 . C <*> 0 . DP=6;I16=5,1,0,0,189,6439,0,0,329,18841,0,0,118,2552,0,0;QS=1,0;MQ0F=0 PL 0,18,146 17 174 . G <*> 0 . DP=7;I16=6,1,0,0,173,5081,0,0,389,22441,0,0,119,2561,0,0;QS=1,0;MQ0F=0 PL 0,21,116 17 175 . C <*> 0 . DP=7;I16=6,1,0,0,258,9650,0,0,389,22441,0,0,121,2577,0,0;QS=1,0;MQ0F=0 PL 0,21,175 17 176 . C <*> 0 . DP=7;I16=6,1,0,0,222,7478,0,0,389,22441,0,0,123,2601,0,0;QS=1,0;MQ0F=0 PL 0,21,152 17 177 . C <*> 0 . DP=7;I16=6,1,0,0,234,7984,0,0,389,22441,0,0,125,2633,0,0;QS=1,0;MQ0F=0 PL 0,21,158 17 178 . A <*> 0 . DP=7;I16=6,1,0,0,252,9264,0,0,389,22441,0,0,127,2673,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 179 . A <*> 0 . DP=7;I16=6,1,0,0,235,8463,0,0,389,22441,0,0,129,2721,0,0;QS=1,0;MQ0F=0 PL 0,21,170 17 180 . A <*> 0 . DP=7;I16=6,1,0,0,204,6776,0,0,389,22441,0,0,131,2777,0,0;QS=1,0;MQ0F=0 PL 0,21,148 17 181 . G <*> 0 . DP=7;I16=6,1,0,0,192,6324,0,0,389,22441,0,0,133,2841,0,0;QS=1,0;MQ0F=0 PL 0,21,142 17 182 . A <*> 0 . DP=7;I16=6,1,0,0,226,7678,0,0,389,22441,0,0,135,2913,0,0;QS=1,0;MQ0F=0 PL 0,21,159 17 183 . C <*> 0 . DP=7;I16=6,1,0,0,190,6076,0,0,389,22441,0,0,137,2993,0,0;QS=1,0;MQ0F=0 PL 0,21,140 17 184 . A <*> 0 . DP=7;I16=6,1,0,0,233,8197,0,0,389,22441,0,0,139,3081,0,0;QS=1,0;MQ0F=0 PL 0,21,163 17 185 . C <*> 0 . DP=7;I16=6,1,0,0,221,7507,0,0,389,22441,0,0,140,3126,0,0;QS=1,0;MQ0F=0 PL 0,21,161 17 186 . G <*> 0 . DP=7;I16=6,1,0,0,174,5044,0,0,389,22441,0,0,141,3177,0,0;QS=1,0;MQ0F=0 PL 0,21,123 17 187 . C <*> 0 . DP=7;I16=6,1,0,0,252,9238,0,0,389,22441,0,0,142,3234,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 188 . C <*> 0 . DP=7;I16=6,1,0,0,239,8387,0,0,389,22441,0,0,143,3297,0,0;QS=1,0;MQ0F=0 PL 0,21,162 17 189 . C <*> 0 . DP=7;I16=6,1,0,0,247,8819,0,0,389,22441,0,0,144,3366,0,0;QS=1,0;MQ0F=0 PL 0,21,167 17 190 . A C,<*> 0 . DP=7;I16=5,1,1,0,219,8109,5,25,329,18841,60,3600,118,2716,25,625;QS=0.976636,0.0233645,0;SGB=-0.379885;RPBZ=0;MQBZ=0.408248;MQSBZ=-2.44949;BQBZ=-1.51357;SCBZ=0;MQ0F=0 PL 0,12,153,18,156,153 17 191 . T <*> 0 . DP=7;I16=6,1,0,0,247,8853,0,0,389,22441,0,0,141,3273,0,0;QS=1,0;MQ0F=0 PL 0,21,169 17 192 . G <*> 0 . DP=7;I16=6,1,0,0,221,7309,0,0,389,22441,0,0,139,3213,0,0;QS=1,0;MQ0F=0 PL 0,21,151 17 193 . T <*> 0 . DP=7;I16=6,1,0,0,229,8027,0,0,389,22441,0,0,137,3161,0,0;QS=1,0;MQ0F=0 PL 0,21,157 17 194 . C <*> 0 . DP=6;I16=5,1,0,0,190,6584,0,0,329,18841,0,0,136,3116,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 195 . C <*> 0 . DP=6;I16=5,1,0,0,216,7916,0,0,329,18841,0,0,135,3077,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 196 . A <*> 0 . DP=6;I16=5,1,0,0,183,6151,0,0,329,18841,0,0,134,3044,0,0;QS=1,0;MQ0F=0 PL 0,18,138 17 197 . G <*> 0 . DP=6;I16=5,1,0,0,182,6006,0,0,329,18841,0,0,133,3017,0,0;QS=1,0;MQ0F=0 PL 0,18,134 17 198 . C <*> 0 . DP=6;I16=5,1,0,0,224,8460,0,0,329,18841,0,0,132,2996,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 199 . T <*> 0 . DP=6;I16=5,1,0,0,205,7417,0,0,329,18841,0,0,131,2981,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 200 . T <*> 0 . DP=6;I16=5,1,0,0,212,7606,0,0,329,18841,0,0,129,2921,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 201 . A <*> 0 . DP=6;I16=5,1,0,0,215,7815,0,0,329,18841,0,0,127,2865,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 202 . A <*> 0 . DP=6;I16=5,1,0,0,222,8430,0,0,329,18841,0,0,125,2813,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 203 . C <*> 0 . DP=6;I16=5,1,0,0,209,7439,0,0,329,18841,0,0,123,2765,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 204 . C <*> 0 . DP=6;I16=5,1,0,0,220,8194,0,0,329,18841,0,0,121,2721,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 205 . T <*> 0 . DP=6;I16=5,1,0,0,238,9464,0,0,329,18841,0,0,119,2681,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 206 . G <*> 0 . DP=6;I16=5,1,0,0,194,6522,0,0,329,18841,0,0,117,2645,0,0;QS=1,0;MQ0F=0 PL 0,18,143 17 207 . C <*> 0 . DP=6;I16=5,1,0,0,205,7051,0,0,329,18841,0,0,115,2613,0,0;QS=1,0;MQ0F=0 PL 0,18,151 17 208 . A <*> 0 . DP=6;I16=5,1,0,0,204,7486,0,0,329,18841,0,0,113,2585,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 209 . T <*> 0 . DP=6;I16=5,1,0,0,198,6710,0,0,329,18841,0,0,111,2561,0,0;QS=1,0;MQ0F=0 PL 0,18,146 17 210 . C <*> 0 . DP=6;I16=5,1,0,0,203,6935,0,0,329,18841,0,0,109,2541,0,0;QS=1,0;MQ0F=0 PL 0,18,151 17 211 . C <*> 0 . DP=6;I16=5,1,0,0,206,7092,0,0,329,18841,0,0,107,2525,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 212 . C <*> 0 . DP=6;I16=5,1,0,0,207,7185,0,0,329,18841,0,0,104,2464,0,0;QS=1,0;MQ0F=0 PL 0,18,152 17 213 . T <*> 0 . DP=6;I16=5,1,0,0,219,8179,0,0,329,18841,0,0,101,2409,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 214 . A <*> 0 . DP=6;I16=5,1,0,0,153,4461,0,0,329,18841,0,0,98,2360,0,0;QS=1,0;MQ0F=0 PL 0,18,120 17 215 . G <*> 0 . DP=5;I16=5,0,0,0,141,4397,0,0,300,18000,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,15,105 17 216 . A <*> 0 . DP=4;I16=4,0,0,0,104,3222,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,85 17 217 . A <*> 0 . DP=4;I16=4,0,0,0,123,3969,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,97 17 218 . G <*> 0 . DP=4;I16=4,0,0,0,143,5137,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 219 . T <*> 0 . DP=4;I16=4,0,0,0,113,3379,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,89 17 220 . G <*> 0 . DP=4;I16=4,0,0,0,105,3129,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,84 17 221 . A <*> 0 . DP=4;I16=4,0,0,0,127,4371,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,101 17 222 . A <*> 0 . DP=4;I16=4,0,0,0,89,2465,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQ0F=0 PL 0,12,73 17 223 . G <*> 0 . DP=4;I16=4,0,0,0,104,2810,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,12,81 17 224 . G <*> 0 . DP=4;I16=4,0,0,0,89,2077,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQ0F=0 PL 0,12,70 17 225 . C <*> 0 . DP=4;I16=4,0,0,0,107,3369,0,0,240,14400,0,0,86,1996,0,0;QS=1,0;MQ0F=0 PL 0,12,86 17 226 . A G,<*> 0 . DP=4;I16=3,0,1,0,98,3430,3,9,180,10800,60,3600,60,1350,25,625;QS=0.960784,0.0392157,0;SGB=-0.379885;RPBZ=-0.447214;MQBZ=0;BQBZ=-1.34164;SCBZ=0;MQ0F=0 PL 0,5,79,9,82,80 17 227 . C <*> 0 . DP=4;I16=4,0,0,0,91,2685,0,0,240,14400,0,0,84,1956,0,0;QS=1,0;MQ0F=0 PL 0,12,75 17 228 . C <*> 0 . DP=4;I16=4,0,0,0,121,3947,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,96 17 229 . G <*> 0 . DP=4;I16=4,0,0,0,91,2097,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQ0F=0 PL 0,12,70 17 230 . C <*> 0 . DP=4;I16=4,0,0,0,127,4101,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQ0F=0 PL 0,12,99 17 231 . C <*> 0 . DP=4;I16=4,0,0,0,103,3217,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQ0F=0 PL 0,12,83 17 232 . C <*> 0 . DP=5;I16=5,0,0,0,134,4302,0,0,300,18000,0,0,79,1891,0,0;QS=1,0;MQ0F=0 PL 0,15,101 17 233 . A <*> 0 . DP=5;I16=5,0,0,0,166,5636,0,0,300,18000,0,0,79,1885,0,0;QS=1,0;MQ0F=0 PL 0,15,119 17 234 . A <*> 0 . DP=5;I16=5,0,0,0,170,5930,0,0,300,18000,0,0,79,1883,0,0;QS=1,0;MQ0F=0 PL 0,15,123 17 235 . A <*> 0 . DP=5;I16=5,0,0,0,155,5325,0,0,300,18000,0,0,78,1836,0,0;QS=1,0;MQ0F=0 PL 0,15,115 17 236 . G <*> 0 . DP=5;I16=5,0,0,0,141,4187,0,0,300,18000,0,0,77,1795,0,0;QS=1,0;MQ0F=0 PL 0,15,103 17 237 . A C,<*> 0 . DP=4;I16=3,0,1,0,109,4005,8,64,180,10800,60,3600,52,1134,25,625;QS=0.931624,0.0683761,0;SGB=-0.379885;RPBZ=0.447214;MQBZ=0;BQBZ=-1.34164;SCBZ=0;MQ0F=0 PL 0,3,84,9,87,87 17 238 . C <*> 0 . DP=4;I16=4,0,0,0,104,2856,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQ0F=0 PL 0,12,82 17 239 . A <*> 0 . DP=4;I16=4,0,0,0,138,4886,0,0,240,14400,0,0,77,1699,0,0;QS=1,0;MQ0F=0 PL 0,12,108 17 240 . C <*> 0 . DP=4;I16=4,0,0,0,136,4700,0,0,240,14400,0,0,76,1626,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 241 . G <*> 0 . DP=4;I16=4,0,0,0,81,1817,0,0,240,14400,0,0,75,1559,0,0;QS=1,0;MQ0F=0 PL 0,12,64 17 242 . C <*> 0 . DP=4;I16=4,0,0,0,119,3707,0,0,240,14400,0,0,74,1498,0,0;QS=1,0;MQ0F=0 PL 0,12,94 17 243 . C <*> 0 . DP=4;I16=4,0,0,0,134,4530,0,0,240,14400,0,0,73,1443,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 244 . C <*> 0 . DP=4;I16=4,0,0,0,136,4690,0,0,240,14400,0,0,72,1394,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 245 . A <*> 0 . DP=4;I16=4,0,0,0,150,5630,0,0,240,14400,0,0,71,1351,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 246 . T <*> 0 . DP=4;I16=4,0,0,0,124,4014,0,0,240,14400,0,0,70,1314,0,0;QS=1,0;MQ0F=0 PL 0,12,98 17 247 . G <*> 0 . DP=4;I16=4,0,0,0,131,4411,0,0,240,14400,0,0,69,1283,0,0;QS=1,0;MQ0F=0 PL 0,12,103 17 248 . T <*> 0 . DP=4;I16=4,0,0,0,147,5451,0,0,240,14400,0,0,68,1258,0,0;QS=1,0;MQ0F=0 PL 0,12,114 17 249 . C <*> 0 . DP=4;I16=4,0,0,0,143,5279,0,0,240,14400,0,0,67,1239,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 250 . C <*> 0 . DP=5;I16=4,1,0,0,179,6489,0,0,269,15241,0,0,65,1177,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 251 . A <*> 0 . DP=5;I16=4,1,0,0,192,7424,0,0,269,15241,0,0,64,1124,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 252 . G <*> 0 . DP=5;I16=4,1,0,0,157,5611,0,0,269,15241,0,0,63,1081,0,0;QS=1,0;MQ0F=0 PL 0,15,126 17 253 . C <*> 0 . DP=6;I16=4,2,0,0,202,7118,0,0,298,16082,0,0,62,1048,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 254 . T <*> 0 . DP=6;I16=4,2,0,0,214,7766,0,0,298,16082,0,0,62,1026,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 255 . T <*> 0 . DP=6;I16=4,2,0,0,213,7635,0,0,298,16082,0,0,62,1016,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 256 . A <*> 0 . DP=6;I16=4,2,0,0,220,8108,0,0,298,16082,0,0,62,1018,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 257 . T <*> 0 . DP=6;I16=4,2,0,0,221,8207,0,0,298,16082,0,0,62,1032,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 258 . T <*> 0 . DP=6;I16=4,2,0,0,206,7344,0,0,298,16082,0,0,61,1007,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 259 . C <*> 0 . DP=6;I16=4,2,0,0,222,8258,0,0,298,16082,0,0,60,992,0,0;QS=1,0;MQ0F=0 PL 0,18,170 17 260 . T <*> 0 . DP=5;I16=3,2,0,0,204,8334,0,0,238,12482,0,0,60,986,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 261 . G <*> 0 . DP=5;I16=3,2,0,0,160,5674,0,0,238,12482,0,0,60,988,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 262 . C <*> 0 . DP=6;I16=3,3,0,0,209,7403,0,0,298,16082,0,0,60,998,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 263 . C <*> 0 . DP=6;I16=3,3,0,0,219,8063,0,0,298,16082,0,0,61,1017,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 264 . C <*> 0 . DP=6;I16=3,3,0,0,226,8602,0,0,298,16082,0,0,62,1046,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 265 . A <*> 0 . DP=5;I16=2,3,0,0,178,6994,0,0,238,12482,0,0,64,1084,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 266 . G <*> 0 . DP=5;I16=2,3,0,0,176,6264,0,0,238,12482,0,0,66,1130,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 267 . T <*> 0 . DP=5;I16=2,3,0,0,182,6638,0,0,238,12482,0,0,68,1184,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 268 . T <*> 0 . DP=5;I16=2,3,0,0,202,8164,0,0,238,12482,0,0,70,1246,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 269 . C <*> 0 . DP=5;I16=2,3,0,0,194,7534,0,0,238,12482,0,0,72,1316,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 270 . C <*> 0 . DP=5;I16=2,3,0,0,181,6567,0,0,238,12482,0,0,74,1394,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 271 . T <*> 0 . DP=5;I16=2,3,0,0,199,8023,0,0,238,12482,0,0,76,1480,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 272 . C <*> 0 . DP=5;I16=2,3,0,0,187,7025,0,0,238,12482,0,0,78,1574,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 273 . T <*> 0 . DP=5;I16=2,3,0,0,204,8344,0,0,238,12482,0,0,80,1676,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 274 . C <*> 0 . DP=5;I16=2,3,0,0,173,6067,0,0,238,12482,0,0,82,1786,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 275 . C <*> 0 . DP=4;I16=1,3,0,0,161,6481,0,0,178,8882,0,0,85,1903,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 276 . A <*> 0 . DP=4;I16=1,3,0,0,173,7535,0,0,178,8882,0,0,87,1975,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 277 . G <*> 0 . DP=4;I16=1,3,0,0,162,6566,0,0,178,8882,0,0,89,2051,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 278 . A <*> 0 . DP=4;I16=1,3,0,0,156,6110,0,0,178,8882,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 279 . A <*> 0 . DP=4;I16=1,3,0,0,165,6831,0,0,178,8882,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 280 . A <*> 0 . DP=4;I16=1,3,0,0,175,7665,0,0,178,8882,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 281 . G <*> 0 . DP=4;I16=1,3,0,0,161,6485,0,0,178,8882,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 282 . G <*> 0 . DP=4;I16=1,3,0,0,159,6351,0,0,178,8882,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 283 . C <*> 0 . DP=5;I16=1,4,0,0,167,6819,0,0,238,12482,0,0,101,2341,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 284 . T <*> 0 . DP=5;I16=1,4,0,0,194,7596,0,0,238,12482,0,0,103,2395,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 285 . G <*> 0 . DP=5;I16=1,4,0,0,188,7198,0,0,238,12482,0,0,105,2453,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 286 . C <*> 0 . DP=5;I16=1,4,0,0,188,7234,0,0,238,12482,0,0,107,2515,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 287 . A <*> 0 . DP=5;I16=1,4,0,0,184,7056,0,0,238,12482,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 288 . T <*> 0 . DP=5;I16=1,4,0,0,202,8180,0,0,238,12482,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 289 . G <*> 0 . DP=5;I16=1,4,0,0,190,7474,0,0,238,12482,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 290 . G <*> 0 . DP=5;I16=1,4,0,0,178,6538,0,0,238,12482,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,15,126 17 291 . T <*> 0 . DP=6;I16=1,5,0,0,204,7806,0,0,298,16082,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,18,138 17 292 . T <*> 0 . DP=6;I16=1,5,0,0,228,8746,0,0,298,16082,0,0,115,2697,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 293 . G <*> 0 . DP=6;I16=1,5,0,0,211,8085,0,0,298,16082,0,0,117,2729,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 294 . A <*> 0 . DP=6;I16=1,5,0,0,231,8927,0,0,298,16082,0,0,119,2765,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 295 . C <*> 0 . DP=6;I16=1,5,0,0,232,9028,0,0,298,16082,0,0,121,2805,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 296 . A <*> 0 . DP=6;I16=1,5,0,0,245,10011,0,0,298,16082,0,0,123,2849,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 297 . C <*> 0 . DP=6;I16=1,5,0,0,230,8956,0,0,298,16082,0,0,125,2897,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 298 . A <*> 0 . DP=7;I16=2,5,0,0,266,10190,0,0,358,19682,0,0,127,2949,0,0;QS=1,0;MQ0F=0 PL 0,21,191 17 299 . C <*> 0 . DP=7;I16=2,5,0,0,268,10372,0,0,358,19682,0,0,130,3006,0,0;QS=1,0;MQ0F=0 PL 0,21,189 17 300 . A <*> 0 . DP=7;I16=2,5,0,0,296,12578,0,0,358,19682,0,0,133,3069,0,0;QS=1,0;MQ0F=0 PL 0,21,210 17 301 . G <*> 0 . DP=7;I16=2,5,0,0,274,10742,0,0,358,19682,0,0,136,3138,0,0;QS=1,0;MQ0F=0 PL 0,21,196 17 302 . T <*> 0 . DP=7;I16=2,5,0,0,283,11451,0,0,358,19682,0,0,139,3213,0,0;QS=1,0;MQ0F=0 PL 0,21,202 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=7;I16=0,0,2,5,0,0,280,11200,0,0,358,19682,0,0,139,3213;QS=0,1;VDB=0.355905;SGB=-0.636426;BQBZ=-1.34164;MQ0F=0 PL 201,21,0 17 303 . G <*> 0 . DP=7;I16=2,5,0,0,280,11264,0,0,358,19682,0,0,144,3330,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 304 . C <*> 0 . DP=8;I16=2,6,0,0,304,11716,0,0,418,23282,0,0,146,3370,0,0;QS=1,0;MQ0F=0 PL 0,24,200 17 305 . C <*> 0 . DP=8;I16=2,6,0,0,318,12738,0,0,418,23282,0,0,149,3415,0,0;QS=1,0;MQ0F=0 PL 0,24,211 17 306 . T <*> 0 . DP=8;I16=2,6,0,0,320,12842,0,0,418,23282,0,0,152,3466,0,0;QS=1,0;MQ0F=0 PL 0,24,217 17 307 . G <*> 0 . DP=8;I16=2,6,0,0,303,11789,0,0,418,23282,0,0,154,3474,0,0;QS=1,0;MQ0F=0 PL 0,24,203 17 308 . C <*> 0 . DP=8;I16=2,6,0,0,266,8912,0,0,418,23282,0,0,156,3490,0,0;QS=1,0;MQ0F=0 PL 0,24,185 17 309 . G <*> 0 . DP=8;I16=2,6,0,0,304,11742,0,0,418,23282,0,0,158,3514,0,0;QS=1,0;MQ0F=0 PL 0,24,205 17 310 . A <*> 0 . DP=8;I16=2,6,0,0,316,12540,0,0,418,23282,0,0,160,3546,0,0;QS=1,0;MQ0F=0 PL 0,24,217 17 311 . C <*> 0 . DP=8;I16=2,6,0,0,315,12457,0,0,418,23282,0,0,162,3586,0,0;QS=1,0;MQ0F=0 PL 0,24,210 17 312 . A <*> 0 . DP=8;I16=2,6,0,0,325,13241,0,0,418,23282,0,0,164,3634,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 313 . A <*> 0 . DP=8;I16=2,6,0,0,319,12881,0,0,418,23282,0,0,166,3690,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 314 . A <*> 0 . DP=8;I16=2,6,0,0,340,14484,0,0,418,23282,0,0,168,3754,0,0;QS=1,0;MQ0F=0 PL 0,24,227 17 315 . G <*> 0 . DP=8;I16=2,6,0,0,335,14055,0,0,418,23282,0,0,170,3826,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 316 . C <*> 0 . DP=8;I16=2,6,0,0,329,13603,0,0,418,23282,0,0,171,3855,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 317 . T <*> 0 . DP=8;I16=2,6,0,0,305,12201,0,0,418,23282,0,0,172,3890,0,0;QS=1,0;MQ0F=0 PL 0,24,206 17 318 . G <*> 0 . DP=8;I16=2,6,0,0,307,12149,0,0,418,23282,0,0,173,3931,0,0;QS=1,0;MQ0F=0 PL 0,24,208 17 319 . A <*> 0 . DP=8;I16=2,6,0,0,290,11364,0,0,418,23282,0,0,174,3978,0,0;QS=1,0;MQ0F=0 PL 0,24,196 17 320 . A <*> 0 . DP=8;I16=2,6,0,0,308,12130,0,0,418,23282,0,0,175,4031,0,0;QS=1,0;MQ0F=0 PL 0,24,211 17 321 . T <*> 0 . DP=8;I16=2,6,0,0,322,12994,0,0,418,23282,0,0,176,4090,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 322 . G <*> 0 . DP=9;I16=2,7,0,0,348,13586,0,0,478,26882,0,0,177,4155,0,0;QS=1,0;MQ0F=0 PL 0,27,223 17 323 . C <*> 0 . DP=9;I16=2,7,0,0,329,12959,0,0,478,26882,0,0,178,4176,0,0;QS=1,0;MQ0F=0 PL 0,27,208 17 324 . T <*> 0 . DP=11;I16=4,7,0,0,411,15559,0,0,598,34082,0,0,179,4203,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 325 . A <*> 0 . DP=11;I16=4,7,0,0,413,15685,0,0,598,34082,0,0,181,4189,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 326 . T <*> 0 . DP=11;I16=4,7,0,0,426,16994,0,0,598,34082,0,0,183,4187,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 327 . C <*> 0 . DP=11;I16=4,7,0,0,418,16012,0,0,598,34082,0,0,185,4197,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 328 . A <*> 0 . DP=11;I16=4,7,0,0,433,17075,0,0,598,34082,0,0,186,4170,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 329 . T <*> 0 . DP=11;I16=4,7,0,0,444,18034,0,0,598,34082,0,0,187,4157,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 330 . T <*> 0 . DP=11;I16=4,7,0,0,437,17577,0,0,598,34082,0,0,187,4107,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 331 . T <*> 0 . DP=12;I16=5,7,0,0,425,15401,0,0,658,37682,0,0,187,4069,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 332 . A <*> 0 . DP=11;I16=4,7,0,0,411,15645,0,0,598,34082,0,0,189,4043,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 333 . A <*> 0 . DP=11;I16=4,7,0,0,405,15523,0,0,598,34082,0,0,191,4029,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 334 . A <*> 0 . DP=11;I16=4,7,0,0,404,15090,0,0,598,34082,0,0,193,4027,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 335 . A G,<*> 0 . DP=12;I16=4,7,1,0,382,13732,4,16,598,34082,60,3600,195,4037,0,0;QS=0.989189,0.0108108,0;SGB=-0.379885;RPBZ=-1.59605;MQBZ=0.447214;MQSBZ=-1.25357;BQBZ=-1.59886;SCBZ=-0.301511;MQ0F=0 PL 0,25,245,33,248,245 17 336 . A <*> 0 . DP=12;I16=5,7,0,0,382,12810,0,0,658,37682,0,0,198,4060,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 337 . C <*> 0 . DP=12;I16=5,7,0,0,443,16735,0,0,658,37682,0,0,200,4048,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 338 . T <*> 0 . DP=12;I16=5,7,0,0,482,19532,0,0,658,37682,0,0,202,4052,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 339 . C <*> 0 . DP=12;I16=5,7,0,0,459,17841,0,0,658,37682,0,0,204,4072,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 340 . C <*> 0 . DP=12;I16=5,7,0,0,446,17110,0,0,658,37682,0,0,206,4108,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 341 . T <*> 0 . DP=12;I16=5,7,0,0,499,20833,0,0,658,37682,0,0,208,4160,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 342 . T <*> 0 . DP=12;I16=5,7,0,0,457,17601,0,0,658,37682,0,0,210,4228,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 343 . G <*> 0 . DP=12;I16=5,7,0,0,460,17826,0,0,658,37682,0,0,212,4312,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 344 . C <*> 0 . DP=12;I16=5,7,0,0,454,17546,0,0,658,37682,0,0,214,4412,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 345 . T <*> 0 . DP=12;I16=5,7,0,0,472,18748,0,0,658,37682,0,0,216,4528,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 346 . G <*> 0 . DP=12;I16=5,7,0,0,452,17412,0,0,658,37682,0,0,218,4660,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 347 . G <*> 0 . DP=12;I16=5,7,0,0,454,17316,0,0,658,37682,0,0,220,4808,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 348 . T <*> 0 . DP=12;I16=5,7,0,0,460,17876,0,0,658,37682,0,0,221,4921,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 349 . T <*> 0 . DP=12;I16=5,7,0,0,473,18923,0,0,658,37682,0,0,222,5048,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 350 . T <*> 0 . DP=11;I16=5,6,0,0,426,16634,0,0,629,36841,0,0,222,5086,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 351 . G <*> 0 . DP=11;I16=5,6,0,0,430,16952,0,0,629,36841,0,0,222,5132,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 352 . A <*> 0 . DP=11;I16=5,6,0,0,414,16100,0,0,629,36841,0,0,222,5186,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 353 . G <*> 0 . DP=10;I16=5,5,0,0,386,15166,0,0,600,36000,0,0,222,5198,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 354 . A <*> 0 . DP=10;I16=5,5,0,0,382,15130,0,0,600,36000,0,0,222,5218,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 355 . G <*> 0 . DP=10;I16=5,5,0,0,374,14380,0,0,600,36000,0,0,222,5246,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 356 . G <*> 0 . DP=10;I16=5,5,0,0,369,14149,0,0,600,36000,0,0,222,5282,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 357 . C <*> 0 . DP=10;I16=5,5,0,0,341,12951,0,0,600,36000,0,0,221,5275,0,0;QS=1,0;MQ0F=0 PL 0,30,252 17 358 . A <*> 0 . DP=10;I16=5,5,0,0,381,14901,0,0,600,36000,0,0,220,5274,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 359 . G <*> 0 . DP=11;I16=5,6,0,0,420,16446,0,0,660,39600,0,0,219,5279,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 360 . A <*> 0 . DP=11;I16=5,6,0,0,427,16793,0,0,660,39600,0,0,219,5291,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 361 . A <*> 0 . DP=11;I16=5,6,0,0,427,16851,0,0,660,39600,0,0,218,5260,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 362 . A <*> 0 . DP=10;I16=5,5,0,0,389,15439,0,0,600,36000,0,0,218,5234,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 363 . A <*> 0 . DP=10;I16=5,5,0,0,382,14788,0,0,600,36000,0,0,218,5212,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 364 . T <*> 0 . DP=10;I16=5,5,0,0,358,13294,0,0,600,36000,0,0,218,5194,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 365 . G <*> 0 . DP=10;I16=5,5,0,0,391,15431,0,0,600,36000,0,0,218,5180,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 366 . A <*> 0 . DP=10;I16=5,5,0,0,376,14352,0,0,600,36000,0,0,217,5121,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 367 . T <*> 0 . DP=10;I16=5,5,0,0,368,13886,0,0,600,36000,0,0,216,5068,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 368 . A <*> 0 . DP=10;I16=5,5,0,0,360,13632,0,0,600,36000,0,0,215,5021,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 369 . T <*> 0 . DP=10;I16=5,5,0,0,386,15176,0,0,600,36000,0,0,214,4980,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 370 . C <*> 0 . DP=10;I16=5,5,0,0,373,14349,0,0,600,36000,0,0,213,4945,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 371 . T <*> 0 . DP=11;I16=5,6,0,0,435,17483,0,0,660,39600,0,0,212,4916,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 372 . C <*> 0 . DP=11;I16=5,6,0,0,422,16450,0,0,660,39600,0,0,212,4894,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 373 . A <*> 0 . DP=11;I16=5,6,0,0,416,16096,0,0,660,39600,0,0,211,4831,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 374 . T <*> 0 . DP=11;I16=5,6,0,0,395,14795,0,0,660,39600,0,0,210,4778,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 375 . A T,<*> 0 . DP=11;I16=5,5,0,1,399,15985,14,196,600,36000,60,3600,205,4719,4,16;QS=0.966102,0.0338983,0;SGB=-0.379885;RPBZ=-1.58474;MQBZ=0;MQSBZ=0;BQBZ=-1.59942;SCBZ=0;MQ0F=0 PL 0,18,255,30,255,255 17 376 . G <*> 0 . DP=11;I16=5,6,0,0,419,16089,0,0,660,39600,0,0,208,4702,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 377 . T <*> 0 . DP=11;I16=5,6,0,0,414,16104,0,0,660,39600,0,0,207,4679,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 378 . T <*> 0 . DP=10;I16=5,5,0,0,399,16003,0,0,600,36000,0,0,207,4665,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 379 . G <*> 0 . DP=10;I16=5,5,0,0,385,14907,0,0,600,36000,0,0,207,4659,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 380 . C <*> 0 . DP=10;I16=5,5,0,0,391,15345,0,0,600,36000,0,0,206,4612,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 381 . T <*> 0 . DP=10;I16=5,5,0,0,415,17335,0,0,600,36000,0,0,205,4575,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 382 . T <*> 0 . DP=10;I16=5,5,0,0,401,16215,0,0,600,36000,0,0,204,4548,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 383 . T <*> 0 . DP=10;I16=5,5,0,0,394,15584,0,0,600,36000,0,0,203,4531,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 384 . A <*> 0 . DP=10;I16=5,5,0,0,370,14282,0,0,600,36000,0,0,202,4524,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 385 . C <*> 0 . DP=10;I16=5,5,0,0,358,13180,0,0,600,36000,0,0,200,4476,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 386 . T <*> 0 . DP=10;I16=5,5,0,0,402,16458,0,0,600,36000,0,0,198,4436,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 387 . T <*> 0 . DP=10;I16=5,5,0,0,397,15951,0,0,600,36000,0,0,196,4404,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 388 . T <*> 0 . DP=10;I16=5,5,0,0,394,15676,0,0,600,36000,0,0,194,4380,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 389 . G <*> 0 . DP=10;I16=5,5,0,0,384,14858,0,0,600,36000,0,0,192,4364,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 390 . C <*> 0 . DP=10;I16=5,5,0,0,377,14407,0,0,600,36000,0,0,190,4356,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 391 . A <*> 0 . DP=10;I16=6,4,0,0,392,15500,0,0,569,33241,0,0,189,4355,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 392 . T <*> 0 . DP=11;I16=7,4,0,0,398,14994,0,0,629,36841,0,0,189,4361,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 393 . A <*> 0 . DP=11;I16=7,4,0,0,413,15853,0,0,629,36841,0,0,190,4376,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 394 . T <*> 0 . DP=11;I16=7,4,0,0,424,16506,0,0,629,36841,0,0,191,4401,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 395 . T <*> 0 . DP=11;I16=7,4,0,0,433,17273,0,0,629,36841,0,0,192,4436,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 396 . T <*> 0 . DP=11;I16=7,4,0,0,436,17446,0,0,629,36841,0,0,193,4481,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 397 . T <*> 0 . DP=11;I16=7,4,0,0,429,16877,0,0,629,36841,0,0,193,4485,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 398 . A <*> 0 . DP=10;I16=6,4,0,0,397,15817,0,0,569,33241,0,0,193,4447,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 399 . A <*> 0 . DP=10;I16=6,4,0,0,400,16172,0,0,569,33241,0,0,193,4417,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 400 . A <*> 0 . DP=11;I16=6,5,0,0,425,16735,0,0,629,36841,0,0,191,4297,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 401 . A C,<*> 0 . DP=11;I16=6,4,0,1,396,15798,8,64,569,33241,60,3600,165,3565,25,625;QS=0.979849,0.0201511,0;SGB=-0.379885;RPBZ=-0.633898;MQBZ=0.316228;MQSBZ=0.912871;BQBZ=-1.58838;SCBZ=0;MQ0F=0 PL 0,22,255,30,255,255 17 402 . T <*> 0 . DP=11;I16=6,5,0,0,415,15961,0,0,629,36841,0,0,189,4097,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 403 . T <*> 0 . DP=11;I16=6,5,0,0,426,16580,0,0,629,36841,0,0,188,4018,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 404 . G <*> 0 . DP=11;I16=6,5,0,0,421,16197,0,0,629,36841,0,0,187,3953,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 405 . T <*> 0 . DP=10;I16=6,4,0,0,387,15059,0,0,569,33241,0,0,187,3901,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 406 . G <*> 0 . DP=10;I16=6,4,0,0,340,12376,0,0,569,33241,0,0,187,3861,0,0;QS=1,0;MQ0F=0 PL 0,30,247 17 407 . A <*> 0 . DP=10;I16=6,4,0,0,380,14678,0,0,569,33241,0,0,186,3784,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 408 . C <*> 0 . DP=10;I16=6,4,0,0,343,12191,0,0,569,33241,0,0,185,3721,0,0;QS=1,0;MQ0F=0 PL 0,30,244 17 409 . T <*> 0 . DP=11;I16=7,4,0,0,400,15038,0,0,629,36841,0,0,184,3672,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 410 . T <*> 0 . DP=11;I16=7,4,0,0,415,16051,0,0,629,36841,0,0,184,3638,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 411 . T <*> 0 . DP=11;I16=7,4,0,0,413,16469,0,0,629,36841,0,0,183,3571,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 412 . C <*> 0 . DP=11;I16=7,4,0,0,413,16037,0,0,629,36841,0,0,182,3522,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 413 . A <*> 0 . DP=11;I16=7,4,0,0,443,17907,0,0,629,36841,0,0,181,3491,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 414 . T <*> 0 . DP=11;I16=7,4,0,0,425,16499,0,0,629,36841,0,0,180,3478,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 415 . G <*> 0 . DP=11;I16=7,4,0,0,397,14511,0,0,629,36841,0,0,179,3483,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 416 . G <*> 0 . DP=11;I16=7,4,0,0,371,13487,0,0,629,36841,0,0,178,3506,0,0;QS=1,0;MQ0F=0 PL 0,33,252 17 417 . C <*> 0 . DP=11;I16=7,4,0,0,394,14514,0,0,629,36841,0,0,176,3496,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 418 . A <*> 0 . DP=11;I16=7,4,0,0,412,15720,0,0,629,36841,0,0,173,3451,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 419 . T <*> 0 . DP=11;I16=7,4,0,0,394,14726,0,0,629,36841,0,0,170,3420,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 420 . A <*> 0 . DP=12;I16=7,5,0,0,423,15455,0,0,689,40441,0,0,167,3403,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 421 . A <*> 0 . DP=14;I16=8,6,0,0,511,19175,0,0,778,44882,0,0,165,3401,0,0;QS=1,0;MQ0F=0 PL 0,42,255 17 422 . A <*> 0 . DP=14;I16=8,6,0,0,488,18180,0,0,778,44882,0,0,165,3417,0,0;QS=1,0;MQ0F=0 PL 0,42,255 17 423 . T <*> 0 . DP=13;I16=8,5,0,0,485,18253,0,0,718,41282,0,0,166,3452,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 424 . A <*> 0 . DP=13;I16=8,5,0,0,455,16265,0,0,718,41282,0,0,167,3505,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 425 . A <*> 0 . DP=11;I16=6,5,0,0,381,13925,0,0,598,34082,0,0,170,3574,0,0;QS=1,0;MQ0F=0 PL 0,33,249 17 426 . T <*> 0 . DP=11;I16=6,5,0,0,323,10647,0,0,598,34082,0,0,172,3606,0,0;QS=1,0;MQ0F=0 PL 0,33,227 17 427 . A <*> 0 . DP=11;I16=6,5,0,0,358,12202,0,0,598,34082,0,0,174,3650,0,0;QS=1,0;MQ0F=0 PL 0,33,242 17 428 . C <*> 0 . DP=11;I16=6,5,0,0,370,12672,0,0,598,34082,0,0,176,3706,0,0;QS=1,0;MQ0F=0 PL 0,33,254 17 429 . T <*> 0 . DP=11;I16=6,5,0,0,401,15207,0,0,598,34082,0,0,178,3774,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 430 . G <*> 0 . DP=11;I16=6,5,0,0,364,12556,0,0,598,34082,0,0,180,3854,0,0;QS=1,0;MQ0F=0 PL 0,33,246 17 431 . G <*> 0 . DP=11;I16=6,5,0,0,319,10457,0,0,598,34082,0,0,182,3946,0,0;QS=1,0;MQ0F=0 PL 0,33,224 17 432 . T <*> 0 . DP=10;I16=5,5,0,0,364,13442,0,0,538,30482,0,0,185,4049,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 433 . T <*> 0 . DP=10;I16=5,5,0,0,322,11360,0,0,538,30482,0,0,188,4162,0,0;QS=1,0;MQ0F=0 PL 0,30,229 17 434 . T <*> 0 . DP=10;I16=5,5,0,0,339,11787,0,0,538,30482,0,0,191,4285,0,0;QS=1,0;MQ0F=0 PL 0,30,243 17 435 . A <*> 0 . DP=10;I16=5,5,0,0,346,12322,0,0,538,30482,0,0,192,4318,0,0;QS=1,0;MQ0F=0 PL 0,30,237 17 436 . T <*> 0 . DP=9;I16=4,5,0,0,305,10551,0,0,478,26882,0,0,194,4360,0,0;QS=1,0;MQ0F=0 PL 0,27,223 17 437 . T G,<*> 0 . DP=9;I16=3,5,1,0,271,9505,6,36,449,26041,29,841,180,4154,16,256;QS=0.978102,0.0218978,0;SGB=-0.379885;RPBZ=-1.36123;MQBZ=-1.87083;MQSBZ=1.69031;BQBZ=-1.55569;SCBZ=0;MQ0F=0 PL 0,17,200,24,203,201 17 438 . A <*> 0 . DP=9;I16=4,5,0,0,298,10570,0,0,478,26882,0,0,198,4468,0,0;QS=1,0;MQ0F=0 PL 0,27,220 17 439 . C <*> 0 . DP=9;I16=4,5,0,0,311,10989,0,0,478,26882,0,0,200,4534,0,0;QS=1,0;MQ0F=0 PL 0,27,224 17 440 . A <*> 0 . DP=9;I16=4,5,0,0,346,13482,0,0,478,26882,0,0,202,4608,0,0;QS=1,0;MQ0F=0 PL 0,27,247 17 441 . G <*> 0 . DP=9;I16=4,5,0,0,278,8848,0,0,478,26882,0,0,204,4690,0,0;QS=1,0;MQ0F=0 PL 0,27,198 17 442 . A <*> 0 . DP=9;I16=4,5,0,0,335,12765,0,0,478,26882,0,0,206,4780,0,0;QS=1,0;MQ0F=0 PL 0,27,233 17 443 . A <*> 0 . DP=9;I16=4,5,0,0,353,13985,0,0,478,26882,0,0,208,4878,0,0;QS=1,0;MQ0F=0 PL 0,27,246 17 444 . G <*> 0 . DP=9;I16=4,5,0,0,314,11134,0,0,478,26882,0,0,210,4984,0,0;QS=1,0;MQ0F=0 PL 0,27,227 17 445 . C <*> 0 . DP=9;I16=4,5,0,0,311,10911,0,0,478,26882,0,0,212,5098,0,0;QS=1,0;MQ0F=0 PL 0,27,219 17 446 . A <*> 0 . DP=9;I16=4,5,0,0,326,12046,0,0,478,26882,0,0,213,5169,0,0;QS=1,0;MQ0F=0 PL 0,27,232 17 447 . C <*> 0 . DP=9;I16=4,5,0,0,329,12167,0,0,478,26882,0,0,211,5095,0,0;QS=1,0;MQ0F=0 PL 0,27,235 17 448 . T <*> 0 . DP=9;I16=4,5,0,0,345,13353,0,0,478,26882,0,0,209,5025,0,0;QS=1,0;MQ0F=0 PL 0,27,240 17 449 . A <*> 0 . DP=9;I16=4,5,0,0,351,13765,0,0,478,26882,0,0,207,4959,0,0;QS=1,0;MQ0F=0 PL 0,27,245 17 450 . G <*> 0 . DP=9;I16=4,5,0,0,318,11826,0,0,478,26882,0,0,205,4897,0,0;QS=1,0;MQ0F=0 PL 0,27,233 17 451 . A <*> 0 . DP=9;I16=4,5,0,0,339,13205,0,0,478,26882,0,0,203,4839,0,0;QS=1,0;MQ0F=0 PL 0,27,244 17 452 . A <*> 0 . DP=9;I16=4,5,0,0,314,12242,0,0,478,26882,0,0,201,4785,0,0;QS=1,0;MQ0F=0 PL 0,27,225 17 453 . A <*> 0 . DP=9;I16=4,5,0,0,296,11552,0,0,478,26882,0,0,199,4735,0,0;QS=1,0;MQ0F=0 PL 0,27,225 17 454 . A <*> 0 . DP=10;I16=5,5,0,0,370,14072,0,0,538,30482,0,0,197,4689,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 455 . T <*> 0 . DP=11;I16=5,6,0,0,390,14176,0,0,575,31851,0,0,196,4648,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 456 . G <*> 0 . DP=11;I16=5,6,0,0,365,12789,0,0,575,31851,0,0,196,4614,0,0;QS=1,0;MQ0F=0 PL 0,33,250 17 457 . C <*> 0 . DP=11;I16=5,6,0,0,382,13622,0,0,575,31851,0,0,196,4588,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 458 . A <*> 0 . DP=11;I16=5,6,0,0,404,15008,0,0,575,31851,0,0,196,4570,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 459 . T <*> 0 . DP=11;I16=5,6,0,0,380,13694,0,0,575,31851,0,0,196,4560,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 460 . G <*> 0 . DP=10;I16=5,5,0,0,366,13542,0,0,515,28251,0,0,197,4557,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 461 . T <*> 0 . DP=10;I16=5,5,0,0,382,15028,0,0,515,28251,0,0,198,4560,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 462 . G <*> 0 . DP=10;I16=5,5,0,0,350,12490,0,0,515,28251,0,0,199,4569,0,0;QS=1,0;MQ0F=0 PL 0,30,241 17 463 . G <*> 0 . DP=10;I16=5,5,0,0,310,10258,0,0,515,28251,0,0,200,4584,0,0;QS=1,0;MQ0F=0 PL 0,30,221 17 464 . A <*> 0 . DP=10;I16=5,5,0,0,304,10594,0,0,515,28251,0,0,201,4605,0,0;QS=1,0;MQ0F=0 PL 0,30,217 17 465 . C T,<*> 0 . DP=10;I16=5,4,0,1,326,11950,4,16,455,24651,60,3600,196,4596,6,36;QS=0.987342,0.0126582,0;SGB=-0.379885;RPBZ=1.57147;MQBZ=0.645497;MQSBZ=0.903696;BQBZ=-1.61645;SCBZ=0;MQ0F=0 PL 0,20,224,27,227,224 17 466 . A <*> 0 . DP=10;I16=5,5,0,0,379,14569,0,0,515,28251,0,0,203,4665,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 467 . A <*> 0 . DP=10;I16=5,5,0,0,367,14303,0,0,515,28251,0,0,203,4655,0,0;QS=1,0;MQ0F=0 PL 0,30,251 17 468 . A <*> 0 . DP=10;I16=5,5,0,0,357,13375,0,0,515,28251,0,0,202,4604,0,0;QS=1,0;MQ0F=0 PL 0,30,251 17 469 . A <*> 0 . DP=10;I16=5,5,0,0,387,15581,0,0,515,28251,0,0,201,4563,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 470 . G <*> 0 . DP=10;I16=5,5,0,0,328,11334,0,0,515,28251,0,0,200,4532,0,0;QS=1,0;MQ0F=0 PL 0,30,238 17 471 . T G,C,<*> 0 . DP=11;I16=5,4,0,2,319,11637,18,162,478,26882,97,4969,183,4255,16,256;QS=0.945289,0.0273556,0.0273556,0;VDB=0.96;SGB=-0.453602;RPBZ=0.23624;MQBZ=-0.451335;MQSBZ=1.04881;BQBZ=-2.14585;SCBZ=0;MQ0F=0 PL 0,19,219,19,221,219,27,222,222,221 17 472 . T <*> 0 . DP=10;I16=5,5,0,0,340,12388,0,0,515,28251,0,0,200,4500,0,0;QS=1,0;MQ0F=0 PL 0,30,241 17 473 . G <*> 0 . DP=10;I16=5,5,0,0,363,14103,0,0,515,28251,0,0,201,4499,0,0;QS=1,0;MQ0F=0 PL 0,30,250 17 474 . G <*> 0 . DP=11;I16=6,5,0,0,378,13788,0,0,575,31851,0,0,202,4508,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 475 . G <*> 0 . DP=11;I16=6,5,0,0,377,13401,0,0,575,31851,0,0,204,4528,0,0;QS=1,0;MQ0F=0 PL 0,33,253 17 476 . A <*> 0 . DP=11;I16=6,5,0,0,404,15370,0,0,575,31851,0,0,205,4511,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 477 . T <*> 0 . DP=11;I16=6,5,0,0,413,15979,0,0,575,31851,0,0,206,4508,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 478 . T <*> 0 . DP=11;I16=6,5,0,0,414,15806,0,0,575,31851,0,0,207,4519,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 479 . A <*> 0 . DP=11;I16=6,5,0,0,441,17977,0,0,575,31851,0,0,208,4544,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 480 . G <*> 0 . DP=11;I16=6,5,0,0,421,16261,0,0,575,31851,0,0,208,4532,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 481 . G <*> 0 . DP=11;I16=6,5,0,0,416,16016,0,0,575,31851,0,0,207,4481,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 482 . A <*> 0 . DP=11;I16=6,5,0,0,434,17374,0,0,575,31851,0,0,206,4440,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 483 . G <*> 0 . DP=11;I16=6,5,0,0,426,16626,0,0,575,31851,0,0,205,4409,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 484 . A <*> 0 . DP=11;I16=6,5,0,0,451,18653,0,0,575,31851,0,0,204,4388,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 485 . G <*> 0 . DP=11;I16=6,5,0,0,419,16073,0,0,575,31851,0,0,202,4328,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 486 . A <*> 0 . DP=11;I16=6,5,0,0,452,18618,0,0,575,31851,0,0,200,4280,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 487 . G <*> 0 . DP=11;I16=6,5,0,0,403,14875,0,0,575,31851,0,0,198,4244,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 488 . A G,<*> 0 . DP=11;I16=5,5,1,0,388,15102,4,16,546,31010,29,841,171,3595,25,625;QS=0.989474,0.0105263,0;SGB=-0.379885;RPBZ=0;MQBZ=-1.81659;MQSBZ=0.699206;BQBZ=-1.60315;SCBZ=0;MQ0F=0 PL 0,23,255,30,255,255 17 489 . A <*> 0 . DP=11;I16=6,5,0,0,393,14565,0,0,575,31851,0,0,194,4208,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 490 . A <*> 0 . DP=11;I16=6,5,0,0,401,14927,0,0,575,31851,0,0,192,4208,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 491 . T <*> 0 . DP=11;I16=6,5,0,0,385,13773,0,0,575,31851,0,0,190,4220,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 492 . G <*> 0 . DP=10;I16=5,5,0,0,367,13741,0,0,546,31010,0,0,189,4243,0,0;QS=1,0;MQ0F=0 PL 0,30,251 17 493 . A <*> 0 . DP=9;I16=4,5,0,0,338,13688,0,0,486,27410,0,0,189,4275,0,0;QS=1,0;MQ0F=0 PL 0,27,242 17 494 . A <*> 0 . DP=9;I16=4,5,0,0,371,15531,0,0,486,27410,0,0,189,4315,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 495 . G <*> 0 . DP=9;I16=4,5,0,0,336,12694,0,0,486,27410,0,0,189,4363,0,0;QS=1,0;MQ0F=0 PL 0,27,244 17 496 . A <*> 0 . DP=9;I16=4,5,0,0,348,13636,0,0,486,27410,0,0,188,4370,0,0;QS=1,0;MQ0F=0 PL 0,27,249 17 497 . C <*> 0 . DP=9;I16=4,5,0,0,334,12616,0,0,486,27410,0,0,184,4238,0,0;QS=1,0;MQ0F=0 PL 0,27,239 17 498 . A <*> 0 . DP=9;I16=4,5,0,0,362,14588,0,0,486,27410,0,0,180,4118,0,0;QS=1,0;MQ0F=0 PL 0,27,252 17 499 . T <*> 0 . DP=10;I16=5,5,0,0,370,13844,0,0,546,31010,0,0,176,4010,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 500 . A <*> 0 . DP=10;I16=5,5,0,0,379,14465,0,0,546,31010,0,0,172,3864,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 501 . T <*> 0 . DP=9;I16=5,4,0,0,345,13407,0,0,486,27410,0,0,169,3729,0,0;QS=1,0;MQ0F=0 PL 0,27,241 17 502 . G <*> 0 . DP=9;I16=5,4,0,0,317,11369,0,0,486,27410,0,0,166,3604,0,0;QS=1,0;MQ0F=0 PL 0,27,235 17 503 . T <*> 0 . DP=9;I16=5,4,0,0,311,11263,0,0,486,27410,0,0,163,3489,0,0;QS=1,0;MQ0F=0 PL 0,27,234 17 504 . C <*> 0 . DP=9;I16=5,4,0,0,295,9993,0,0,486,27410,0,0,160,3384,0,0;QS=1,0;MQ0F=0 PL 0,27,219 17 505 . C <*> 0 . DP=9;I16=5,4,0,0,299,10467,0,0,486,27410,0,0,157,3289,0,0;QS=1,0;MQ0F=0 PL 0,27,221 17 506 . A <*> 0 . DP=9;I16=5,4,0,0,310,10972,0,0,486,27410,0,0,154,3204,0,0;QS=1,0;MQ0F=0 PL 0,27,231 17 507 . C <*> 0 . DP=9;I16=5,4,0,0,311,10937,0,0,486,27410,0,0,151,3129,0,0;QS=1,0;MQ0F=0 PL 0,27,226 17 508 . A <*> 0 . DP=9;I16=5,4,0,0,306,11130,0,0,486,27410,0,0,148,3064,0,0;QS=1,0;MQ0F=0 PL 0,27,220 17 509 . C <*> 0 . DP=9;I16=5,4,0,0,339,12893,0,0,486,27410,0,0,145,3009,0,0;QS=1,0;MQ0F=0 PL 0,27,241 17 510 . A <*> 0 . DP=8;I16=4,4,0,0,292,10906,0,0,426,23810,0,0,143,2963,0,0;QS=1,0;MQ0F=0 PL 0,24,221 17 511 . A <*> 0 . DP=8;I16=4,4,0,0,311,12335,0,0,426,23810,0,0,141,2925,0,0;QS=1,0;MQ0F=0 PL 0,24,233 17 512 . A <*> 0 . DP=8;I16=4,4,0,0,309,12187,0,0,426,23810,0,0,139,2895,0,0;QS=1,0;MQ0F=0 PL 0,24,231 17 513 . A <*> 0 . DP=8;I16=4,4,0,0,310,12250,0,0,426,23810,0,0,137,2873,0,0;QS=1,0;MQ0F=0 PL 0,24,233 17 514 . A <*> 0 . DP=8;I16=4,4,0,0,313,12385,0,0,426,23810,0,0,135,2859,0,0;QS=1,0;MQ0F=0 PL 0,24,235 17 515 . C <*> 0 . DP=8;I16=4,4,0,0,272,9636,0,0,426,23810,0,0,133,2853,0,0;QS=1,0;MQ0F=0 PL 0,24,211 17 516 . C <*> 0 . DP=8;I16=4,4,0,0,280,10438,0,0,426,23810,0,0,131,2855,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 517 . T <*> 0 . DP=8;I16=4,4,0,0,330,13694,0,0,426,23810,0,0,129,2865,0,0;QS=1,0;MQ0F=0 PL 0,24,242 17 518 . G <*> 0 . DP=8;I16=4,4,0,0,289,10617,0,0,426,23810,0,0,127,2883,0,0;QS=1,0;MQ0F=0 PL 0,24,220 17 519 . T <*> 0 . DP=8;I16=4,4,0,0,305,11719,0,0,426,23810,0,0,125,2909,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 520 . T <*> 0 . DP=8;I16=4,4,0,0,298,11414,0,0,426,23810,0,0,123,2943,0,0;QS=1,0;MQ0F=0 PL 0,24,223 17 521 . C <*> 0 . DP=7;I16=4,3,0,0,271,10919,0,0,366,20210,0,0,122,2984,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 522 . A <*> 0 . DP=5;I16=3,2,0,0,200,8046,0,0,277,15769,0,0,123,3029,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 523 . T <*> 0 . DP=5;I16=3,2,0,0,202,8354,0,0,277,15769,0,0,124,3076,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 524 . T <*> 0 . DP=5;I16=3,2,0,0,172,6578,0,0,277,15769,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 525 . G <*> 0 . DP=5;I16=3,2,0,0,155,5751,0,0,277,15769,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 526 . C <*> 0 . DP=5;I16=3,2,0,0,159,6097,0,0,277,15769,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,137 17 527 . A <*> 0 . DP=6;I16=4,2,0,0,220,8220,0,0,337,19369,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 528 . G <*> 0 . DP=6;I16=4,2,0,0,236,9362,0,0,337,19369,0,0,126,3126,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 529 . C <*> 0 . DP=6;I16=4,2,0,0,231,9215,0,0,337,19369,0,0,127,3129,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 530 . T <*> 0 . DP=6;I16=4,2,0,0,252,10690,0,0,337,19369,0,0,127,3085,0,0;QS=1,0;MQ0F=0 PL 0,18,202 17 531 . T <*> 0 . DP=6;I16=4,2,0,0,239,9609,0,0,337,19369,0,0,126,2996,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 532 . T <*> 0 . DP=6;I16=4,2,0,0,234,9212,0,0,337,19369,0,0,125,2913,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 533 . C <*> 0 . DP=6;I16=4,2,0,0,220,8368,0,0,337,19369,0,0,124,2836,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 534 . T <*> 0 . DP=6;I16=4,2,0,0,255,10895,0,0,337,19369,0,0,123,2765,0,0;QS=1,0;MQ0F=0 PL 0,18,205 17 535 . A <*> 0 . DP=6;I16=4,2,0,0,231,8961,0,0,337,19369,0,0,122,2700,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 536 . C <*> 0 . DP=6;I16=4,2,0,0,195,7075,0,0,337,19369,0,0,121,2641,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 537 . C <*> 0 . DP=6;I16=4,2,0,0,222,8546,0,0,337,19369,0,0,120,2588,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 538 . A <*> 0 . DP=6;I16=4,2,0,0,222,8490,0,0,337,19369,0,0,119,2541,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 539 . T <*> 0 . DP=6;I16=4,2,0,0,222,8412,0,0,337,19369,0,0,118,2500,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 540 . C <*> 0 . DP=6;I16=4,2,0,0,218,8258,0,0,337,19369,0,0,117,2465,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 541 . A <*> 0 . DP=6;I16=4,2,0,0,198,7414,0,0,337,19369,0,0,116,2436,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 542 . C <*> 0 . DP=6;I16=4,2,0,0,212,7902,0,0,337,19369,0,0,115,2413,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 543 . C <*> 0 . DP=6;I16=4,2,0,0,230,9164,0,0,337,19369,0,0,114,2396,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 544 . A <*> 0 . DP=6;I16=4,2,0,0,223,8733,0,0,337,19369,0,0,113,2385,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 545 . A <*> 0 . DP=6;I16=4,2,0,0,230,9494,0,0,337,19369,0,0,112,2380,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 546 . A <*> 0 . DP=6;I16=4,2,0,0,236,9540,0,0,337,19369,0,0,111,2381,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 547 . A <*> 0 . DP=6;I16=4,2,0,0,240,9712,0,0,337,19369,0,0,109,2339,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 548 . A <*> 0 . DP=7;I16=4,3,0,0,261,10277,0,0,397,22969,0,0,107,2305,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 549 . T <*> 0 . DP=7;I16=4,3,0,0,266,10342,0,0,397,22969,0,0,106,2280,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 550 . T <*> 0 . DP=7;I16=4,3,0,0,275,10863,0,0,397,22969,0,0,104,2216,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 551 . G <*> 0 . DP=7;I16=4,3,0,0,259,9883,0,0,397,22969,0,0,102,2164,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 552 . C <*> 0 . DP=7;I16=4,3,0,0,260,10162,0,0,397,22969,0,0,100,2124,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 553 . A <*> 0 . DP=8;I16=5,3,0,0,263,9695,0,0,457,26569,0,0,97,2045,0,0;QS=1,0;MQ0F=0 PL 0,24,203 17 554 . A <*> 0 . DP=8;I16=5,3,0,0,287,10801,0,0,457,26569,0,0,95,1977,0,0;QS=1,0;MQ0F=0 PL 0,24,221 17 555 . A <*> 0 . DP=7;I16=4,3,0,0,262,10108,0,0,397,22969,0,0,94,1920,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 556 . C <*> 0 . DP=6;I16=4,2,0,0,227,8701,0,0,360,21600,0,0,94,1872,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 557 . A <*> 0 . DP=6;I16=4,2,0,0,226,8674,0,0,360,21600,0,0,94,1832,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 558 . A <*> 0 . DP=6;I16=4,2,0,0,215,8343,0,0,360,21600,0,0,94,1800,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 559 . C <*> 0 . DP=6;I16=4,2,0,0,204,7318,0,0,360,21600,0,0,94,1776,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 560 . C <*> 0 . DP=7;I16=5,2,0,0,230,8132,0,0,420,25200,0,0,94,1760,0,0;QS=1,0;MQ0F=0 PL 0,21,181 17 561 . A <*> 0 . DP=7;I16=5,2,0,0,254,9682,0,0,420,25200,0,0,95,1753,0,0;QS=1,0;MQ0F=0 PL 0,21,194 17 562 . C <*> 0 . DP=7;I16=5,2,0,0,243,8835,0,0,420,25200,0,0,96,1756,0,0;QS=1,0;MQ0F=0 PL 0,21,187 17 563 . A <*> 0 . DP=7;I16=5,2,0,0,227,8179,0,0,420,25200,0,0,97,1769,0,0;QS=1,0;MQ0F=0 PL 0,21,179 17 564 . C <*> 0 . DP=7;I16=5,2,0,0,233,8027,0,0,420,25200,0,0,98,1792,0,0;QS=1,0;MQ0F=0 PL 0,21,182 17 565 . G <*> 0 . DP=7;I16=5,2,0,0,195,5883,0,0,420,25200,0,0,99,1825,0,0;QS=1,0;MQ0F=0 PL 0,21,154 17 566 . C <*> 0 . DP=7;I16=5,2,0,0,214,8154,0,0,420,25200,0,0,100,1868,0,0;QS=1,0;MQ0F=0 PL 0,21,170 17 567 . C <*> 0 . DP=7;I16=5,2,0,0,249,9141,0,0,420,25200,0,0,101,1921,0,0;QS=1,0;MQ0F=0 PL 0,21,194 17 568 . C <*> 0 . DP=7;I16=5,2,0,0,243,9175,0,0,420,25200,0,0,102,1984,0,0;QS=1,0;MQ0F=0 PL 0,21,193 17 569 . T <*> 0 . DP=7;I16=5,2,0,0,277,11475,0,0,420,25200,0,0,103,2057,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 570 . T <*> 0 . DP=7;I16=5,2,0,0,250,9228,0,0,420,25200,0,0,104,2140,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 571 . C <*> 0 . DP=7;I16=5,2,0,0,246,9120,0,0,420,25200,0,0,105,2233,0,0;QS=1,0;MQ0F=0 PL 0,21,193 17 572 . A <*> 0 . DP=6;I16=5,1,0,0,229,8933,0,0,360,21600,0,0,107,2335,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 573 . A <*> 0 . DP=6;I16=5,1,0,0,235,9257,0,0,360,21600,0,0,109,2445,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 574 . C <*> 0 . DP=6;I16=5,1,0,0,227,8679,0,0,360,21600,0,0,110,2512,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 575 . T <*> 0 . DP=5;I16=4,1,0,0,197,7967,0,0,300,18000,0,0,111,2535,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 576 . G <*> 0 . DP=5;I16=4,1,0,0,182,6904,0,0,300,18000,0,0,112,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 577 . G <*> 0 . DP=5;I16=4,1,0,0,176,6414,0,0,300,18000,0,0,113,2599,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 578 . G <*> 0 . DP=5;I16=4,1,0,0,182,6814,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 579 . G <*> 0 . DP=5;I16=4,1,0,0,167,6833,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 580 . A <*> 0 . DP=5;I16=4,1,0,0,189,7293,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 581 . A <*> 0 . DP=5;I16=4,1,0,0,183,7019,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 582 . C <*> 0 . DP=5;I16=4,1,0,0,182,6834,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 583 . T <*> 0 . DP=5;I16=4,1,0,0,196,7912,0,0,300,18000,0,0,114,2660,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 584 . C <*> 0 . DP=5;I16=4,1,0,0,191,7427,0,0,300,18000,0,0,114,2676,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 585 . A <*> 0 . DP=5;I16=4,1,0,0,191,7395,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 586 . T <*> 0 . DP=5;I16=4,1,0,0,189,7311,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 587 . C <*> 0 . DP=5;I16=4,1,0,0,188,7274,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 588 . A <*> 0 . DP=5;I16=4,1,0,0,202,8170,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 589 . A <*> 0 . DP=5;I16=4,1,0,0,204,8332,0,0,300,18000,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 590 . C <*> 0 . DP=6;I16=4,2,0,0,212,7662,0,0,360,21600,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 591 . A <*> 0 . DP=6;I16=4,2,0,0,228,8752,0,0,360,21600,0,0,109,2565,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 592 . A <*> 0 . DP=6;I16=4,2,0,0,219,8323,0,0,360,21600,0,0,109,2553,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 593 . C <*> 0 . DP=6;I16=4,2,0,0,209,7587,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 594 . A <*> 0 . DP=8;I16=5,3,0,0,277,9873,0,0,480,28800,0,0,109,2541,0,0;QS=1,0;MQ0F=0 PL 0,24,213 17 595 . A <*> 0 . DP=8;I16=5,3,0,0,285,10329,0,0,480,28800,0,0,111,2543,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 596 . A <*> 0 . DP=8;I16=5,3,0,0,306,11784,0,0,480,28800,0,0,113,2553,0,0;QS=1,0;MQ0F=0 PL 0,24,231 17 597 . C <*> 0 . DP=8;I16=5,3,0,0,290,10586,0,0,480,28800,0,0,115,2571,0,0;QS=1,0;MQ0F=0 PL 0,24,220 17 598 . T <*> 0 . DP=9;I16=5,4,0,0,319,12649,0,0,540,32400,0,0,121,2613,0,0;QS=1,0;MQ0F=0 PL 0,27,242 17 599 . T <*> 0 . DP=9;I16=5,4,0,0,335,12557,0,0,540,32400,0,0,124,2656,0,0;QS=1,0;MQ0F=0 PL 0,27,247 17 600 . G <*> 0 . DP=8;I16=4,4,0,0,303,11515,0,0,480,28800,0,0,128,2708,0,0;QS=1,0;MQ0F=0 PL 0,24,232 17 601 . T <*> 0 . DP=8;I16=4,4,0,0,305,11697,0,0,480,28800,0,0,132,2768,0,0;QS=1,0;MQ0F=0 PL 0,24,235 17 602 . G <*> 0 . DP=8;I16=4,4,0,0,298,11176,0,0,480,28800,0,0,136,2836,0,0;QS=1,0;MQ0F=0 PL 0,24,229 17 603 . G <*> 0 . DP=8;I16=4,4,0,0,277,9947,0,0,480,28800,0,0,139,2863,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 604 . T G,<*> 0 . DP=8;I16=3,4,1,0,265,10121,4,16,420,25200,60,3600,117,2275,25,625;QS=0.98513,0.0148699,0;SGB=-0.379885;RPBZ=0.219529;MQBZ=0;MQSBZ=0;BQBZ=-1.52753;SCBZ=-0.377964;MQ0F=0 PL 0,15,205,21,208,205 17 605 . T <*> 0 . DP=8;I16=4,4,0,0,273,10339,0,0,480,28800,0,0,145,2947,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 606 . T <*> 0 . DP=8;I16=4,4,0,0,278,9966,0,0,480,28800,0,0,148,3004,0,0;QS=1,0;MQ0F=0 PL 0,24,217 17 607 . A <*> 0 . DP=8;I16=4,4,0,0,288,10428,0,0,480,28800,0,0,151,3071,0,0;QS=1,0;MQ0F=0 PL 0,24,222 17 608 . C <*> 0 . DP=9;I16=4,5,0,0,287,9495,0,0,540,32400,0,0,154,3148,0,0;QS=1,0;MQ0F=0 PL 0,27,214 17 609 . C <*> 0 . DP=9;I16=4,5,0,0,323,11717,0,0,540,32400,0,0,158,3236,0,0;QS=1,0;MQ0F=0 PL 0,27,238 17 610 . C <*> 0 . DP=9;I16=4,5,0,0,335,12565,0,0,540,32400,0,0,162,3336,0,0;QS=1,0;MQ0F=0 PL 0,27,246 17 611 . A <*> 0 . DP=9;I16=4,5,0,0,333,12435,0,0,540,32400,0,0,166,3448,0,0;QS=1,0;MQ0F=0 PL 0,27,246 17 612 . C <*> 0 . DP=9;I16=4,5,0,0,340,12944,0,0,540,32400,0,0,170,3572,0,0;QS=1,0;MQ0F=0 PL 0,27,250 17 613 . A <*> 0 . DP=9;I16=4,5,0,0,321,11719,0,0,540,32400,0,0,174,3708,0,0;QS=1,0;MQ0F=0 PL 0,27,239 17 614 . C <*> 0 . DP=9;I16=4,5,0,0,328,12204,0,0,540,32400,0,0,178,3856,0,0;QS=1,0;MQ0F=0 PL 0,27,245 17 615 . A <*> 0 . DP=9;I16=4,5,0,0,344,13326,0,0,540,32400,0,0,182,4016,0,0;QS=1,0;MQ0F=0 PL 0,27,254 17 616 . A <*> 0 . DP=9;I16=4,5,0,0,350,13768,0,0,540,32400,0,0,185,4137,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 617 . T <*> 0 . DP=9;I16=4,5,0,0,351,13831,0,0,540,32400,0,0,188,4268,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 618 . G <*> 0 . DP=9;I16=4,5,0,0,323,11839,0,0,540,32400,0,0,191,4409,0,0;QS=1,0;MQ0F=0 PL 0,27,240 17 619 . G <*> 0 . DP=9;I16=4,5,0,0,336,12598,0,0,540,32400,0,0,194,4560,0,0;QS=1,0;MQ0F=0 PL 0,27,247 17 620 . A <*> 0 . DP=9;I16=4,5,0,0,346,13546,0,0,540,32400,0,0,194,4568,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 621 . A <*> 0 . DP=9;I16=4,5,0,0,353,14067,0,0,540,32400,0,0,194,4580,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 622 . G <*> 0 . DP=9;I16=4,5,0,0,339,12831,0,0,540,32400,0,0,194,4596,0,0;QS=1,0;MQ0F=0 PL 0,27,249 17 623 . A <*> 0 . DP=9;I16=4,5,0,0,347,13467,0,0,540,32400,0,0,194,4616,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 624 . C <*> 0 . DP=9;I16=4,5,0,0,325,12051,0,0,540,32400,0,0,193,4591,0,0;QS=1,0;MQ0F=0 PL 0,27,242 17 625 . C <*> 0 . DP=9;I16=4,5,0,0,336,12700,0,0,540,32400,0,0,192,4572,0,0;QS=1,0;MQ0F=0 PL 0,27,249 17 626 . A <*> 0 . DP=9;I16=4,5,0,0,337,12659,0,0,540,32400,0,0,191,4559,0,0;QS=1,0;MQ0F=0 PL 0,27,247 17 627 . C <*> 0 . DP=9;I16=4,5,0,0,344,13286,0,0,540,32400,0,0,190,4552,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 628 . T <*> 0 . DP=8;I16=3,5,0,0,329,13595,0,0,480,28800,0,0,190,4550,0,0;QS=1,0;MQ0F=0 PL 0,24,249 17 629 . T <*> 0 . DP=8;I16=3,5,0,0,296,11158,0,0,480,28800,0,0,189,4503,0,0;QS=1,0;MQ0F=0 PL 0,24,226 17 630 . A <*> 0 . DP=8;I16=3,5,0,0,308,12256,0,0,480,28800,0,0,188,4462,0,0;QS=1,0;MQ0F=0 PL 0,24,235 17 631 . G <*> 0 . DP=8;I16=3,5,0,0,288,10864,0,0,480,28800,0,0,187,4427,0,0;QS=1,0;MQ0F=0 PL 0,24,223 17 632 . C <*> 0 . DP=8;I16=3,5,0,0,291,10911,0,0,480,28800,0,0,186,4398,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 633 . A <*> 0 . DP=8;I16=3,5,0,0,280,9994,0,0,480,28800,0,0,185,4375,0,0;QS=1,0;MQ0F=0 PL 0,24,214 17 634 . A <*> 0 . DP=8;I16=3,5,0,0,301,11703,0,0,480,28800,0,0,183,4307,0,0;QS=1,0;MQ0F=0 PL 0,24,229 17 635 . C <*> 0 . DP=8;I16=3,5,0,0,301,11435,0,0,480,28800,0,0,181,4243,0,0;QS=1,0;MQ0F=0 PL 0,24,229 17 636 . A <*> 0 . DP=8;I16=3,5,0,0,322,12992,0,0,480,28800,0,0,178,4134,0,0;QS=1,0;MQ0F=0 PL 0,24,243 17 637 . A <*> 0 . DP=8;I16=3,5,0,0,320,12852,0,0,480,28800,0,0,175,4031,0,0;QS=1,0;MQ0F=0 PL 0,24,242 17 638 . A <*> 0 . DP=8;I16=3,5,0,0,314,12420,0,0,480,28800,0,0,172,3934,0,0;QS=1,0;MQ0F=0 PL 0,24,238 17 639 . A <*> 0 . DP=8;I16=3,5,0,0,297,11189,0,0,480,28800,0,0,169,3843,0,0;QS=1,0;MQ0F=0 PL 0,24,227 17 640 . A <*> 0 . DP=8;I16=3,5,0,0,313,12331,0,0,480,28800,0,0,166,3758,0,0;QS=1,0;MQ0F=0 PL 0,24,240 17 641 . G <*> 0 . DP=8;I16=3,5,0,0,284,10334,0,0,480,28800,0,0,163,3679,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 642 . G <*> 0 . DP=8;I16=3,5,0,0,288,10596,0,0,480,28800,0,0,160,3606,0,0;QS=1,0;MQ0F=0 PL 0,24,221 17 643 . A <*> 0 . DP=8;I16=3,5,0,0,314,12368,0,0,480,28800,0,0,157,3539,0,0;QS=1,0;MQ0F=0 PL 0,24,237 17 644 . C <*> 0 . DP=8;I16=3,5,0,0,267,9111,0,0,480,28800,0,0,154,3478,0,0;QS=1,0;MQ0F=0 PL 0,24,204 17 645 . C <*> 0 . DP=8;I16=3,5,0,0,298,11200,0,0,480,28800,0,0,151,3423,0,0;QS=1,0;MQ0F=0 PL 0,24,226 17 646 . A <*> 0 . DP=9;I16=3,6,0,0,317,11507,0,0,540,32400,0,0,148,3374,0,0;QS=1,0;MQ0F=0 PL 0,27,229 17 647 . A <*> 0 . DP=10;I16=3,7,0,0,312,10158,0,0,600,36000,0,0,146,3332,0,0;QS=1,0;MQ0F=0 PL 0,30,216 17 648 . A <*> 0 . DP=10;I16=3,7,0,0,278,8284,0,0,600,36000,0,0,145,3299,0,0;QS=1,0;MQ0F=0 PL 0,30,195 17 649 . C <*> 0 . DP=9;I16=3,6,0,0,296,10124,0,0,540,32400,0,0,145,3275,0,0;QS=1,0;MQ0F=0 PL 0,27,217 17 650 . T <*> 0 . DP=9;I16=3,6,0,0,299,11099,0,0,540,32400,0,0,145,3259,0,0;QS=1,0;MQ0F=0 PL 0,27,225 17 651 . C <*> 0 . DP=9;I16=3,6,0,0,315,11203,0,0,540,32400,0,0,145,3251,0,0;QS=1,0;MQ0F=0 PL 0,27,229 17 652 . C <*> 0 . DP=9;I16=3,6,0,0,297,10979,0,0,540,32400,0,0,145,3251,0,0;QS=1,0;MQ0F=0 PL 0,27,215 17 653 . T <*> 0 . DP=8;I16=2,6,0,0,313,12301,0,0,480,28800,0,0,145,3259,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 654 . G <*> 0 . DP=8;I16=2,6,0,0,306,11846,0,0,480,28800,0,0,146,3274,0,0;QS=1,0;MQ0F=0 PL 0,24,223 17 655 . G <*> 0 . DP=8;I16=2,6,0,0,294,10942,0,0,480,28800,0,0,147,3295,0,0;QS=1,0;MQ0F=0 PL 0,24,213 17 656 . T <*> 0 . DP=8;I16=2,6,0,0,293,10849,0,0,480,28800,0,0,148,3322,0,0;QS=1,0;MQ0F=0 PL 0,24,213 17 657 . A <*> 0 . DP=8;I16=2,6,0,0,262,9218,0,0,480,28800,0,0,149,3355,0,0;QS=1,0;MQ0F=0 PL 0,24,191 17 658 . C <*> 0 . DP=8;I16=2,6,0,0,292,10812,0,0,480,28800,0,0,150,3394,0,0;QS=1,0;MQ0F=0 PL 0,24,211 17 659 . A <*> 0 . DP=8;I16=2,6,0,0,296,11228,0,0,480,28800,0,0,151,3439,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 660 . T <*> 0 . DP=8;I16=2,6,0,0,295,11195,0,0,480,28800,0,0,152,3490,0,0;QS=1,0;MQ0F=0 PL 0,24,214 17 661 . G <*> 0 . DP=7;I16=1,6,0,0,269,10375,0,0,420,25200,0,0,154,3546,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 662 . C <*> 0 . DP=7;I16=1,6,0,0,264,10078,0,0,420,25200,0,0,156,3606,0,0;QS=1,0;MQ0F=0 PL 0,21,187 17 663 . A <*> 0 . DP=7;I16=1,6,0,0,258,9846,0,0,420,25200,0,0,158,3670,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 664 . A <*> 0 . DP=7;I16=1,6,0,0,260,9752,0,0,420,25200,0,0,160,3738,0,0;QS=1,0;MQ0F=0 PL 0,21,184 17 665 . C <*> 0 . DP=7;I16=1,6,0,0,259,9715,0,0,420,25200,0,0,162,3810,0,0;QS=1,0;MQ0F=0 PL 0,21,184 17 666 . T <*> 0 . DP=7;I16=1,6,0,0,276,10958,0,0,420,25200,0,0,163,3837,0,0;QS=1,0;MQ0F=0 PL 0,21,194 17 667 . G <*> 0 . DP=7;I16=1,6,0,0,265,10139,0,0,420,25200,0,0,164,3870,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 668 . A <*> 0 . DP=7;I16=1,6,0,0,264,10108,0,0,420,25200,0,0,165,3909,0,0;QS=1,0;MQ0F=0 PL 0,21,187 17 669 . C <*> 0 . DP=7;I16=1,6,0,0,268,10318,0,0,420,25200,0,0,166,3954,0,0;QS=1,0;MQ0F=0 PL 0,21,189 17 670 . A <*> 0 . DP=7;I16=1,6,0,0,289,11969,0,0,420,25200,0,0,164,3858,0,0;QS=1,0;MQ0F=0 PL 0,21,205 17 671 . G <*> 0 . DP=7;I16=1,6,0,0,270,10482,0,0,420,25200,0,0,162,3774,0,0;QS=1,0;MQ0F=0 PL 0,21,191 17 672 . A <*> 0 . DP=7;I16=1,6,0,0,264,10000,0,0,420,25200,0,0,159,3651,0,0;QS=1,0;MQ0F=0 PL 0,21,185 17 673 . T <*> 0 . DP=7;I16=1,6,0,0,272,10602,0,0,420,25200,0,0,155,3487,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 674 . G <*> 0 . DP=7;I16=1,6,0,0,263,9939,0,0,420,25200,0,0,151,3331,0,0;QS=1,0;MQ0F=0 PL 0,21,185 17 675 . A <*> 0 . DP=7;I16=1,6,0,0,270,10454,0,0,420,25200,0,0,147,3183,0,0;QS=1,0;MQ0F=0 PL 0,21,189 17 676 . A <*> 0 . DP=7;I16=1,6,0,0,265,10085,0,0,420,25200,0,0,143,3043,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 677 . T <*> 0 . DP=7;I16=1,6,0,0,275,10823,0,0,420,25200,0,0,139,2911,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 678 . C <*> 0 . DP=7;I16=1,6,0,0,271,10551,0,0,420,25200,0,0,135,2787,0,0;QS=1,0;MQ0F=0 PL 0,21,191 17 679 . T <*> 0 . DP=7;I16=1,6,0,0,278,11086,0,0,420,25200,0,0,131,2671,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 680 . C <*> 0 . DP=7;I16=1,6,0,0,259,9627,0,0,420,25200,0,0,127,2563,0,0;QS=1,0;MQ0F=0 PL 0,21,181 17 681 . A <*> 0 . DP=7;I16=1,6,0,0,246,8758,0,0,420,25200,0,0,123,2463,0,0;QS=1,0;MQ0F=0 PL 0,21,174 17 682 . A <*> 0 . DP=7;I16=1,6,0,0,247,8871,0,0,420,25200,0,0,119,2371,0,0;QS=1,0;MQ0F=0 PL 0,21,176 17 683 . A <*> 0 . DP=7;I16=1,6,0,0,230,8064,0,0,420,25200,0,0,115,2287,0,0;QS=1,0;MQ0F=0 PL 0,21,167 17 684 . C <*> 0 . DP=7;I16=1,6,0,0,203,6051,0,0,420,25200,0,0,110,2162,0,0;QS=1,0;MQ0F=0 PL 0,21,145 17 685 . G <*> 0 . DP=7;I16=1,6,0,0,245,8825,0,0,420,25200,0,0,105,2047,0,0;QS=1,0;MQ0F=0 PL 0,21,175 17 686 . C <*> 0 . DP=7;I16=1,6,0,0,257,9479,0,0,420,25200,0,0,100,1942,0,0;QS=1,0;MQ0F=0 PL 0,21,180 17 687 . A <*> 0 . DP=7;I16=1,6,0,0,242,8624,0,0,420,25200,0,0,95,1847,0,0;QS=1,0;MQ0F=0 PL 0,21,174 17 688 . T <*> 0 . DP=7;I16=1,6,0,0,264,10042,0,0,420,25200,0,0,90,1762,0,0;QS=1,0;MQ0F=0 PL 0,21,187 17 689 . T <*> 0 . DP=7;I16=1,6,0,0,261,9799,0,0,420,25200,0,0,85,1687,0,0;QS=1,0;MQ0F=0 PL 0,21,185 17 690 . C <*> 0 . DP=7;I16=1,6,0,0,236,8034,0,0,420,25200,0,0,80,1622,0,0;QS=1,0;MQ0F=0 PL 0,21,166 17 691 . C <*> 0 . DP=6;I16=1,5,0,0,210,7444,0,0,360,21600,0,0,76,1566,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 692 . T <*> 0 . DP=6;I16=1,5,0,0,212,7840,0,0,360,21600,0,0,72,1518,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 693 . C <*> 0 . DP=7;I16=1,6,0,0,245,8643,0,0,420,25200,0,0,68,1478,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 694 . C <*> 0 . DP=7;I16=1,6,0,0,210,6392,0,0,420,25200,0,0,65,1447,0,0;QS=1,0;MQ0F=0 PL 0,21,148 17 695 . G <*> 0 . DP=5;I16=0,5,0,0,175,6167,0,0,300,18000,0,0,65,1423,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 696 . T <*> 0 . DP=5;I16=0,5,0,0,200,8004,0,0,300,18000,0,0,66,1404,0,0;QS=1,0;MQ0F=0 PL 0,15,141 17 697 . G <*> 0 . DP=5;I16=0,5,0,0,167,5661,0,0,300,18000,0,0,67,1391,0,0;QS=1,0;MQ0F=0 PL 0,15,120 17 698 . T <*> 0 . DP=5;I16=0,5,0,0,185,6863,0,0,300,18000,0,0,68,1384,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 699 . G <*> 0 . DP=6;I16=0,6,0,0,188,6962,0,0,329,18841,0,0,72,1392,0,0;QS=1,0;MQ0F=0 PL 0,18,131 17 700 . A <*> 0 . DP=6;I16=0,6,0,0,225,8515,0,0,329,18841,0,0,74,1404,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 701 . A <*> 0 . DP=6;I16=0,6,0,0,221,8249,0,0,329,18841,0,0,76,1424,0,0;QS=1,0;MQ0F=0 PL 0,18,144 17 702 . A <*> 0 . DP=6;I16=0,6,0,0,249,10353,0,0,329,18841,0,0,78,1452,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 703 . G <*> 0 . DP=6;I16=0,6,0,0,222,8300,0,0,329,18841,0,0,80,1488,0,0;QS=1,0;MQ0F=0 PL 0,18,144 17 704 . A <*> 0 . DP=6;I16=0,6,0,0,211,7523,0,0,329,18841,0,0,82,1532,0,0;QS=1,0;MQ0F=0 PL 0,18,139 17 705 . A <*> 0 . DP=6;I16=0,6,0,0,242,9832,0,0,329,18841,0,0,84,1584,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 706 . G <*> 0 . DP=6;I16=0,6,0,0,203,6969,0,0,329,18841,0,0,86,1644,0,0;QS=1,0;MQ0F=0 PL 0,18,131 17 707 . C <*> 0 . DP=6;I16=0,6,0,0,200,6874,0,0,329,18841,0,0,88,1712,0,0;QS=1,0;MQ0F=0 PL 0,18,134 17 708 . C <*> 0 . DP=6;I16=0,6,0,0,169,4803,0,0,329,18841,0,0,90,1788,0,0;QS=1,0;MQ0F=0 PL 0,18,110 17 709 . G <*> 0 . DP=5;I16=0,5,0,0,182,6858,0,0,269,15241,0,0,93,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 710 . G <*> 0 . DP=5;I16=0,5,0,0,164,5932,0,0,269,15241,0,0,96,1960,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 711 . A <*> 0 . DP=6;I16=0,6,0,0,214,7818,0,0,298,16082,0,0,124,2680,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 712 . C <*> 0 . DP=6;I16=0,6,0,0,228,8740,0,0,298,16082,0,0,127,2781,0,0;QS=1,0;MQ0F=0 PL 0,18,146 17 713 . T <*> 0 . DP=6;I16=0,6,0,0,225,8639,0,0,298,16082,0,0,130,2888,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 714 . C <*> 0 . DP=6;I16=0,6,0,0,183,6221,0,0,298,16082,0,0,133,3001,0,0;QS=1,0;MQ0F=0 PL 0,18,127 17 715 . A C,<*> 0 . DP=6;I16=0,5,0,1,162,5642,6,36,269,15241,29,841,117,2759,19,361;QS=0.964286,0.0357143,0;SGB=-0.379885;RPBZ=-0.87831;MQBZ=-1.41421;BQBZ=-1.48522;SCBZ=1.03923;MQ0F=0 PL 0,9,114,15,117,115 17 716 . C <*> 0 . DP=6;I16=0,6,0,0,215,7981,0,0,298,16082,0,0,139,3245,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 717 . A <*> 0 . DP=6;I16=0,6,0,0,229,9051,0,0,298,16082,0,0,142,3376,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 718 . G <*> 0 . DP=6;I16=0,6,0,0,209,7521,0,0,298,16082,0,0,145,3513,0,0;QS=1,0;MQ0F=0 PL 0,18,139 17 719 . G <*> 0 . DP=6;I16=0,6,0,0,172,6190,0,0,298,16082,0,0,147,3605,0,0;QS=1,0;MQ0F=0 PL 0,18,124 17 720 . G <*> 0 . DP=6;I16=0,6,0,0,235,9247,0,0,298,16082,0,0,149,3701,0,0;QS=1,0;MQ0F=0 PL 0,18,147 17 721 . C <*> 0 . DP=6;I16=0,6,0,0,227,8683,0,0,298,16082,0,0,150,3750,0,0;QS=1,0;MQ0F=0 PL 0,18,147 17 722 . A <*> 0 . DP=6;I16=0,6,0,0,218,8102,0,0,298,16082,0,0,149,3701,0,0;QS=1,0;MQ0F=0 PL 0,18,143 17 723 . A G,<*> 0 . DP=6;I16=0,5,0,1,196,7704,7,49,269,15241,29,841,122,2980,25,625;QS=0.964103,0.0358974,0;SGB=-0.379885;RPBZ=-1.46385;MQBZ=-1.41421;BQBZ=-1.48522;SCBZ=1.73205;MQ0F=0 PL 0,9,129,15,132,130 17 724 . C <*> 0 . DP=6;I16=0,6,0,0,216,8000,0,0,298,16082,0,0,145,3513,0,0;QS=1,0;MQ0F=0 PL 0,18,140 17 725 . A <*> 0 . DP=6;I16=0,6,0,0,211,7579,0,0,298,16082,0,0,143,3425,0,0;QS=1,0;MQ0F=0 PL 0,18,137 17 726 . C <*> 0 . DP=6;I16=0,6,0,0,199,6927,0,0,298,16082,0,0,141,3341,0,0;QS=1,0;MQ0F=0 PL 0,18,136 17 727 . A C,<*> 0 . DP=6;I16=0,5,0,1,173,6285,17,289,269,15241,29,841,114,2636,25,625;QS=0.908108,0.0918919,0;SGB=-0.379885;RPBZ=-1.46385;MQBZ=-1.41421;BQBZ=-1.46385;SCBZ=1.03923;MQ0F=0 PL 0,1,109,15,112,119 17 728 . C <*> 0 . DP=6;I16=0,6,0,0,214,7890,0,0,298,16082,0,0,137,3185,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 729 . T <*> 0 . DP=6;I16=0,6,0,0,215,7867,0,0,298,16082,0,0,135,3113,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 730 . A <*> 0 . DP=6;I16=0,6,0,0,198,7286,0,0,298,16082,0,0,133,3045,0,0;QS=1,0;MQ0F=0 PL 0,18,137 17 731 . T <*> 0 . DP=6;I16=0,6,0,0,219,8327,0,0,298,16082,0,0,131,2981,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 732 . C <*> 0 . DP=6;I16=0,6,0,0,190,6622,0,0,298,16082,0,0,129,2921,0,0;QS=1,0;MQ0F=0 PL 0,18,132 17 733 . T C,<*> 0 . DP=6;I16=0,5,0,1,186,7036,4,16,269,15241,29,841,102,2240,25,625;QS=0.978947,0.0210526,0;SGB=-0.379885;RPBZ=-1.46385;MQBZ=-1.41421;BQBZ=-1.48522;SCBZ=1.03923;MQ0F=0 PL 0,10,128,15,131,129 17 734 . G <*> 0 . DP=6;I16=0,6,0,0,212,7610,0,0,298,16082,0,0,125,2813,0,0;QS=1,0;MQ0F=0 PL 0,18,139 17 735 . A <*> 0 . DP=7;I16=0,7,0,0,235,8595,0,0,358,19682,0,0,123,2765,0,0;QS=1,0;MQ0F=0 PL 0,21,150 17 736 . C <*> 0 . DP=7;I16=0,7,0,0,239,9173,0,0,358,19682,0,0,122,2722,0,0;QS=1,0;MQ0F=0 PL 0,21,152 17 737 . T <*> 0 . DP=7;I16=0,7,0,0,235,8339,0,0,358,19682,0,0,121,2685,0,0;QS=1,0;MQ0F=0 PL 0,21,149 17 738 . G <*> 0 . DP=7;I16=0,7,0,0,227,8177,0,0,358,19682,0,0,120,2654,0,0;QS=1,0;MQ0F=0 PL 0,21,141 17 739 . T <*> 0 . DP=7;I16=0,7,0,0,256,9646,0,0,358,19682,0,0,119,2629,0,0;QS=1,0;MQ0F=0 PL 0,21,155 17 740 . T <*> 0 . DP=7;I16=0,7,0,0,248,9042,0,0,358,19682,0,0,118,2610,0,0;QS=1,0;MQ0F=0 PL 0,21,155 17 741 . T <*> 0 . DP=7;I16=0,7,0,0,244,8970,0,0,358,19682,0,0,116,2548,0,0;QS=1,0;MQ0F=0 PL 0,21,151 17 742 . C <*> 0 . DP=7;I16=0,7,0,0,212,7112,0,0,358,19682,0,0,114,2494,0,0;QS=1,0;MQ0F=0 PL 0,21,138 17 743 . A C,<*> 0 . DP=7;I16=0,6,0,1,189,6467,10,100,329,18841,29,841,87,1823,25,625;QS=0.949749,0.0502513,0;SGB=-0.379885;RPBZ=-1;MQBZ=-1.58114;BQBZ=-1.5;SCBZ=-0.408248;MQ0F=0 PL 0,10,123,18,126,126 17 744 . T <*> 0 . DP=7;I16=0,7,0,0,259,9751,0,0,358,19682,0,0,110,2410,0,0;QS=1,0;MQ0F=0 PL 0,21,154 17 745 . G <*> 0 . DP=8;I16=1,7,0,0,280,10088,0,0,418,23282,0,0,108,2380,0,0;QS=1,0;MQ0F=0 PL 0,24,182 17 746 . G <*> 0 . DP=8;I16=1,7,0,0,274,9756,0,0,418,23282,0,0,107,2359,0,0;QS=1,0;MQ0F=0 PL 0,24,178 17 747 . G <*> 0 . DP=7;I16=1,6,0,0,249,9075,0,0,358,19682,0,0,107,2347,0,0;QS=1,0;MQ0F=0 PL 0,21,174 17 748 . A <*> 0 . DP=6;I16=1,5,0,0,207,7619,0,0,298,16082,0,0,108,2342,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 749 . A <*> 0 . DP=6;I16=1,5,0,0,216,7972,0,0,298,16082,0,0,109,2343,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 750 . A <*> 0 . DP=6;I16=1,5,0,0,207,7991,0,0,298,16082,0,0,110,2350,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 751 . G <*> 0 . DP=6;I16=1,5,0,0,190,6410,0,0,298,16082,0,0,111,2363,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 752 . T <*> 0 . DP=6;I16=1,5,0,0,184,5942,0,0,298,16082,0,0,112,2382,0,0;QS=1,0;MQ0F=0 PL 0,18,143 17 753 . C <*> 0 . DP=6;I16=1,5,0,0,208,7512,0,0,298,16082,0,0,113,2407,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 754 . T <*> 0 . DP=6;I16=1,5,0,0,234,9250,0,0,298,16082,0,0,114,2438,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 755 . G <*> 0 . DP=6;I16=1,5,0,0,220,8164,0,0,298,16082,0,0,115,2475,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 756 . G <*> 0 . DP=6;I16=1,5,0,0,200,7040,0,0,298,16082,0,0,116,2518,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 757 . A C,<*> 0 . DP=6;I16=1,4,0,1,187,7063,9,81,269,15241,29,841,92,1942,25,625;QS=0.953608,0.0463918,0;SGB=-0.379885;RPBZ=-0.29277;MQBZ=-1.41421;MQSBZ=-0.707107;BQBZ=-1.48522;SCBZ=-0.447214;MQ0F=0 PL 0,8,144,15,147,146 17 758 . A <*> 0 . DP=6;I16=1,5,0,0,205,7219,0,0,298,16082,0,0,118,2622,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 759 . A G,<*> 0 . DP=6;I16=1,4,0,1,181,6927,4,16,269,15241,29,841,113,2647,6,36;QS=0.978378,0.0216216,0;SGB=-0.379885;RPBZ=1.46385;MQBZ=-1.41421;MQSBZ=-0.707107;BQBZ=-1.46385;SCBZ=2.23607;MQ0F=0 PL 0,10,145,15,148,145 17 760 . C <*> 0 . DP=7;I16=1,6,0,0,171,4987,0,0,358,19682,0,0,120,2750,0,0;QS=1,0;MQ0F=0 PL 0,21,130 17 761 . G <*> 0 . DP=7;I16=1,6,0,0,203,7135,0,0,358,19682,0,0,121,2773,0,0;QS=1,0;MQ0F=0 PL 0,21,155 17 762 . G <*> 0 . DP=7;I16=1,6,0,0,249,9197,0,0,358,19682,0,0,122,2802,0,0;QS=1,0;MQ0F=0 PL 0,21,173 17 763 . C A,<*> 0 . DP=7;I16=1,5,0,1,223,8479,15,225,329,18841,29,841,121,2833,2,4;QS=0.936975,0.0630252,0;SGB=-0.379885;RPBZ=1.5;MQBZ=-1.58114;MQSBZ=-0.632456;BQBZ=-1.51357;SCBZ=2.44949;MQ0F=0 PL 0,6,158,18,161,165 17 764 . A C,<*> 0 . DP=7;I16=1,5,0,1,211,7679,8,64,329,18841,29,841,99,2253,25,625;QS=0.96347,0.0365297,0;SGB=-0.379885;RPBZ=0;MQBZ=-1.58114;MQSBZ=-0.632456;BQBZ=-1.52753;SCBZ=-0.408248;MQ0F=0 PL 0,11,156,18,159,158 17 765 . A <*> 0 . DP=7;I16=1,6,0,0,237,8863,0,0,358,19682,0,0,125,2925,0,0;QS=1,0;MQ0F=0 PL 0,21,170 17 766 . C <*> 0 . DP=6;I16=1,5,0,0,219,8097,0,0,329,18841,0,0,127,2977,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 767 . A <*> 0 . DP=6;I16=1,5,0,0,187,6311,0,0,329,18841,0,0,129,3033,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 768 . C <*> 0 . DP=6;I16=1,5,0,0,237,9391,0,0,329,18841,0,0,131,3093,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 769 . C <*> 0 . DP=6;I16=1,5,0,0,238,9482,0,0,329,18841,0,0,132,3108,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 770 . A <*> 0 . DP=6;I16=1,5,0,0,233,9073,0,0,329,18841,0,0,133,3129,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 771 . T <*> 0 . DP=6;I16=1,5,0,0,243,9941,0,0,329,18841,0,0,132,3056,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 772 . T <*> 0 . DP=6;I16=1,5,0,0,242,9776,0,0,329,18841,0,0,130,2940,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 773 . G <*> 0 . DP=6;I16=1,5,0,0,233,9111,0,0,329,18841,0,0,128,2832,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 774 . A <*> 0 . DP=6;I16=1,5,0,0,246,10094,0,0,329,18841,0,0,126,2732,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 775 . G <*> 0 . DP=6;I16=1,5,0,0,237,9391,0,0,329,18841,0,0,124,2640,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 776 . A <*> 0 . DP=6;I16=1,5,0,0,228,8798,0,0,329,18841,0,0,122,2556,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 777 . C <*> 0 . DP=6;I16=1,5,0,0,221,8245,0,0,329,18841,0,0,120,2480,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 778 . A <*> 0 . DP=6;I16=1,5,0,0,246,10108,0,0,329,18841,0,0,118,2412,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 779 . G <*> 0 . DP=6;I16=1,5,0,0,219,8227,0,0,329,18841,0,0,116,2352,0,0;QS=1,0;MQ0F=0 PL 0,18,170 17 780 . A <*> 0 . DP=6;I16=1,5,0,0,217,7995,0,0,329,18841,0,0,114,2300,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 781 . A C,<*> 0 . DP=6;I16=1,4,0,1,196,7720,10,100,300,18000,29,841,97,2031,15,225;QS=0.951456,0.0485437,0;SGB=-0.379885;RPBZ=0.29277;MQBZ=-2.23607;MQSBZ=-0.447214;BQBZ=-1.48522;SCBZ=0;MQ0F=0 PL 0,7,150,15,153,154 17 782 . A <*> 0 . DP=6;I16=1,5,0,0,223,8435,0,0,329,18841,0,0,110,2220,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 783 . A <*> 0 . DP=7;I16=1,6,0,0,248,9014,0,0,389,22441,0,0,108,2192,0,0;QS=1,0;MQ0F=0 PL 0,21,178 17 784 . C <*> 0 . DP=7;I16=1,6,0,0,259,9613,0,0,389,22441,0,0,107,2173,0,0;QS=1,0;MQ0F=0 PL 0,21,178 17 785 . A <*> 0 . DP=7;I16=1,6,0,0,278,11086,0,0,389,22441,0,0,106,2164,0,0;QS=1,0;MQ0F=0 PL 0,21,187 17 786 . G <*> 0 . DP=7;I16=1,6,0,0,256,9458,0,0,389,22441,0,0,104,2114,0,0;QS=1,0;MQ0F=0 PL 0,21,180 17 787 . G <*> 0 . DP=7;I16=1,6,0,0,254,9236,0,0,389,22441,0,0,102,2072,0,0;QS=1,0;MQ0F=0 PL 0,21,175 17 788 . T <*> 0 . DP=7;I16=1,6,0,0,273,10665,0,0,389,22441,0,0,100,2038,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 789 . G <*> 0 . DP=7;I16=1,6,0,0,262,9868,0,0,389,22441,0,0,98,2012,0,0;QS=1,0;MQ0F=0 PL 0,21,183 17 790 . A <*> 0 . DP=7;I16=1,6,0,0,295,12443,0,0,389,22441,0,0,96,1994,0,0;QS=1,0;MQ0F=0 PL 0,21,201 17 791 . G <*> 0 . DP=7;I16=1,6,0,0,252,9098,0,0,389,22441,0,0,94,1984,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 792 . T <*> 0 . DP=7;I16=1,6,0,0,251,9043,0,0,389,22441,0,0,92,1982,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 793 . G <*> 0 . DP=7;I16=1,6,0,0,251,9025,0,0,389,22441,0,0,90,1988,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 794 . G <*> 0 . DP=6;I16=1,5,0,0,219,8009,0,0,329,18841,0,0,89,2001,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 795 . T <*> 0 . DP=6;I16=1,5,0,0,219,8087,0,0,329,18841,0,0,88,2020,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 796 . T <*> 0 . DP=5;I16=1,4,0,0,184,6874,0,0,269,15241,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 797 . G <*> 0 . DP=4;I16=1,3,0,0,154,5958,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 798 . C <*> 0 . DP=4;I16=1,3,0,0,143,5191,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 799 . C <*> 0 . DP=4;I16=1,3,0,0,156,6106,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 800 . T <*> 0 . DP=4;I16=1,3,0,0,158,6300,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 801 . G <*> 0 . DP=4;I16=1,3,0,0,164,6742,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 802 . G <*> 0 . DP=4;I16=1,3,0,0,155,6075,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 803 . G <*> 0 . DP=4;I16=1,3,0,0,154,5956,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 804 . G <*> 0 . DP=4;I16=1,3,0,0,157,6185,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 805 . C <*> 0 . DP=4;I16=1,3,0,0,147,5417,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 806 . C <*> 0 . DP=4;I16=1,3,0,0,137,4781,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 807 . A <*> 0 . DP=4;I16=1,3,0,0,166,6930,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 808 . G <*> 0 . DP=4;I16=1,3,0,0,155,6029,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 809 . G <*> 0 . DP=4;I16=1,3,0,0,155,6053,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 810 . G <*> 0 . DP=4;I16=1,3,0,0,150,5676,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 811 . A <*> 0 . DP=4;I16=1,3,0,0,159,6323,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 812 . A <*> 0 . DP=4;I16=1,3,0,0,157,6231,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 813 . C <*> 0 . DP=4;I16=1,3,0,0,157,6195,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 814 . T <*> 0 . DP=4;I16=1,3,0,0,170,7226,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 815 . T <*> 0 . DP=4;I16=1,3,0,0,163,6687,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 816 . T <*> 0 . DP=4;I16=1,3,0,0,154,5954,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 817 . C <*> 0 . DP=4;I16=1,3,0,0,140,5032,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 818 . T <*> 0 . DP=4;I16=1,3,0,0,163,6657,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 819 . G <*> 0 . DP=4;I16=1,3,0,0,161,6481,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 820 . G <*> 0 . DP=4;I16=1,3,0,0,154,5958,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 821 . G <*> 0 . DP=4;I16=1,3,0,0,161,6493,0,0,240,14400,0,0,88,2022,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 822 . G <*> 0 . DP=4;I16=1,3,0,0,144,5218,0,0,240,14400,0,0,86,1948,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 823 . T <*> 0 . DP=4;I16=1,3,0,0,146,5614,0,0,240,14400,0,0,84,1878,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 824 . C <*> 0 . DP=4;I16=1,3,0,0,125,4633,0,0,240,14400,0,0,82,1812,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 825 . A <*> 0 . DP=4;I16=1,3,0,0,132,4446,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 826 . T <*> 0 . DP=4;I16=1,3,0,0,133,4477,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 827 . A <*> 0 . DP=4;I16=1,3,0,0,139,4901,0,0,240,14400,0,0,76,1638,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 828 . T C,<*> 0 . DP=4;I16=0,0,1,3,0,0,135,4719,0,0,240,14400,0,0,74,1588;QS=0,1,0;VDB=0.292086;SGB=-0.556411;MQSBZ=0;MQ0F=0 PL 120,12,0,120,12,120 17 829 . T <*> 0 . DP=4;I16=1,3,0,0,149,5635,0,0,240,14400,0,0,72,1542,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 830 . C <*> 0 . DP=4;I16=1,3,0,0,153,5865,0,0,240,14400,0,0,70,1500,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 831 . T <*> 0 . DP=4;I16=1,3,0,0,151,5761,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 832 . C <*> 0 . DP=4;I16=1,3,0,0,139,4905,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 833 . T <*> 0 . DP=5;I16=1,4,0,0,185,6853,0,0,300,18000,0,0,64,1398,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 834 . G A,<*> 0 . DP=5;I16=0,0,1,4,0,0,163,5375,0,0,300,18000,0,0,63,1373;QS=0,1,0;VDB=0.877481;SGB=-0.590765;MQSBZ=0;MQ0F=0 PL 133,15,0,133,15,133 17 835 . T <*> 0 . DP=5;I16=1,4,0,0,164,5828,0,0,300,18000,0,0,62,1354,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 836 . G <*> 0 . DP=4;I16=1,3,0,0,149,5551,0,0,240,14400,0,0,61,1291,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 837 . T <*> 0 . DP=4;I16=1,3,0,0,161,6499,0,0,240,14400,0,0,60,1234,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 838 . T <*> 0 . DP=4;I16=1,3,0,0,153,5859,0,0,240,14400,0,0,59,1183,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 839 . G <*> 0 . DP=5;I16=1,4,0,0,163,6495,0,0,300,18000,0,0,69,1259,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 840 . A <*> 0 . DP=6;I16=2,4,0,0,214,7770,0,0,360,21600,0,0,69,1243,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 841 . T <*> 0 . DP=6;I16=2,4,0,0,225,8485,0,0,360,21600,0,0,70,1236,0,0;QS=1,0;MQ0F=0 PL 0,18,185 17 842 . T <*> 0 . DP=6;I16=2,4,0,0,213,7643,0,0,360,21600,0,0,71,1239,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 843 . C <*> 0 . DP=6;I16=2,4,0,0,194,6400,0,0,360,21600,0,0,72,1252,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 844 . T <*> 0 . DP=6;I16=2,4,0,0,232,8996,0,0,360,21600,0,0,73,1275,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 845 . G <*> 0 . DP=7;I16=3,4,0,0,250,8956,0,0,420,25200,0,0,74,1308,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 846 . G <*> 0 . DP=6;I16=2,4,0,0,200,6776,0,0,360,21600,0,0,77,1351,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 847 . T <*> 0 . DP=6;I16=2,4,0,0,183,5629,0,0,360,21600,0,0,80,1404,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 848 . G <*> 0 . DP=6;I16=2,4,0,0,202,6952,0,0,360,21600,0,0,83,1467,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 849 . G <*> 0 . DP=6;I16=2,4,0,0,168,5294,0,0,360,21600,0,0,86,1540,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 850 . T <*> 0 . DP=6;I16=2,4,0,0,178,5468,0,0,360,21600,0,0,89,1623,0,0;QS=1,0;MQ0F=0 PL 0,18,147 17 851 . G <*> 0 . DP=6;I16=2,4,0,0,189,6065,0,0,360,21600,0,0,92,1716,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 852 . G <*> 0 . DP=6;I16=2,4,0,0,178,5790,0,0,360,21600,0,0,95,1819,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 853 . A <*> 0 . DP=6;I16=2,4,0,0,200,6944,0,0,360,21600,0,0,98,1932,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 854 . A <*> 0 . DP=6;I16=2,4,0,0,204,7078,0,0,360,21600,0,0,100,2004,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 855 . A <*> 0 . DP=6;I16=2,4,0,0,179,6005,0,0,360,21600,0,0,102,2084,0,0;QS=1,0;MQ0F=0 PL 0,18,152 17 856 . C <*> 0 . DP=6;I16=2,4,0,0,208,7382,0,0,360,21600,0,0,104,2172,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 857 . A <*> 0 . DP=7;I16=3,4,0,0,242,8476,0,0,420,25200,0,0,106,2268,0,0;QS=1,0;MQ0F=0 PL 0,21,194 17 858 . A <*> 0 . DP=7;I16=3,4,0,0,245,9151,0,0,420,25200,0,0,109,2373,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 859 . G <*> 0 . DP=7;I16=3,4,0,0,254,9300,0,0,420,25200,0,0,110,2388,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 860 . A <*> 0 . DP=7;I16=3,4,0,0,233,8223,0,0,420,25200,0,0,111,2413,0,0;QS=1,0;MQ0F=0 PL 0,21,190 17 861 . C <*> 0 . DP=6;I16=3,3,0,0,189,6345,0,0,360,21600,0,0,113,2447,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 862 . T <*> 0 . DP=6;I16=3,3,0,0,210,7702,0,0,360,21600,0,0,115,2489,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 863 . G <*> 0 . DP=6;I16=3,3,0,0,214,7702,0,0,360,21600,0,0,117,2539,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 864 . T <*> 0 . DP=6;I16=3,3,0,0,215,7757,0,0,360,21600,0,0,119,2597,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 865 . C <*> 0 . DP=6;I16=3,3,0,0,210,7508,0,0,360,21600,0,0,121,2663,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 866 . C <*> 0 . DP=6;I16=3,3,0,0,210,7530,0,0,360,21600,0,0,122,2686,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 867 . C <*> 0 . DP=6;I16=3,3,0,0,222,8294,0,0,360,21600,0,0,123,2715,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 868 . A <*> 0 . DP=6;I16=3,3,0,0,241,9703,0,0,360,21600,0,0,124,2750,0,0;QS=1,0;MQ0F=0 PL 0,18,202 17 869 . G <*> 0 . DP=6;I16=3,3,0,0,223,8357,0,0,360,21600,0,0,125,2791,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 870 . C <*> 0 . DP=6;I16=3,3,0,0,223,8379,0,0,360,21600,0,0,126,2838,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 871 . C <*> 0 . DP=6;I16=3,3,0,0,228,8746,0,0,360,21600,0,0,126,2840,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 872 . T <*> 0 . DP=6;I16=3,3,0,0,224,8456,0,0,360,21600,0,0,126,2846,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 873 . G <*> 0 . DP=6;I16=3,3,0,0,217,7917,0,0,360,21600,0,0,126,2856,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 874 . G <*> 0 . DP=6;I16=3,3,0,0,225,8529,0,0,360,21600,0,0,126,2870,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 875 . G <*> 0 . DP=6;I16=3,3,0,0,188,6376,0,0,360,21600,0,0,126,2888,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 876 . T <*> 0 . DP=6;I16=3,3,0,0,206,7160,0,0,360,21600,0,0,126,2910,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 877 . G <*> 0 . DP=6;I16=3,3,0,0,208,7336,0,0,360,21600,0,0,126,2936,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 878 . A <*> 0 . DP=6;I16=3,3,0,0,229,8757,0,0,360,21600,0,0,126,2966,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 879 . T <*> 0 . DP=6;I16=3,3,0,0,221,8157,0,0,360,21600,0,0,126,3000,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 880 . A <*> 0 . DP=6;I16=3,3,0,0,203,7047,0,0,360,21600,0,0,126,3038,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 881 . C <*> 0 . DP=6;I16=3,3,0,0,218,8024,0,0,360,21600,0,0,126,3080,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 882 . A <*> 0 . DP=6;I16=3,3,0,0,238,9516,0,0,360,21600,0,0,126,3126,0,0;QS=1,0;MQ0F=0 PL 0,18,200 17 883 . G <*> 0 . DP=6;I16=3,3,0,0,208,7448,0,0,360,21600,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 884 . C <*> 0 . DP=5;I16=3,2,0,0,165,5551,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 885 . G <*> 0 . DP=5;I16=3,2,0,0,149,4587,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 886 . A <*> 0 . DP=5;I16=3,2,0,0,187,7107,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 887 . G <*> 0 . DP=5;I16=3,2,0,0,170,6022,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 888 . A <*> 0 . DP=5;I16=3,2,0,0,155,5423,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 889 . C <*> 0 . DP=5;I16=3,2,0,0,184,6828,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 890 . C <*> 0 . DP=5;I16=3,2,0,0,174,6238,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 891 . C <*> 0 . DP=5;I16=3,2,0,0,189,7251,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 892 . C <*> 0 . DP=5;I16=3,2,0,0,191,7399,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 893 . A <*> 0 . DP=5;I16=3,2,0,0,191,7367,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 894 . T <*> 0 . DP=5;I16=3,2,0,0,190,7260,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 895 . C <*> 0 . DP=5;I16=3,2,0,0,186,7026,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 896 . T <*> 0 . DP=5;I16=3,2,0,0,207,8587,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,180 17 897 . C <*> 0 . DP=5;I16=3,2,0,0,191,7331,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 898 . T <*> 0 . DP=5;I16=3,2,0,0,198,7966,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 899 . A <*> 0 . DP=5;I16=3,2,0,0,168,6022,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 900 . C <*> 0 . DP=5;I16=3,2,0,0,190,7260,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 901 . C <*> 0 . DP=5;I16=3,2,0,0,193,7563,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 902 . A <*> 0 . DP=5;I16=3,2,0,0,201,8083,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 903 . A <*> 0 . DP=5;I16=3,2,0,0,197,7839,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 904 . A <*> 0 . DP=5;I16=3,2,0,0,199,7985,0,0,300,18000,0,0,124,3076,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 905 . A <*> 0 . DP=5;I16=3,2,0,0,197,7933,0,0,300,18000,0,0,123,3029,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 906 . A <*> 0 . DP=5;I16=3,2,0,0,190,7450,0,0,300,18000,0,0,122,2984,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 907 . A <*> 0 . DP=5;I16=3,2,0,0,189,7249,0,0,300,18000,0,0,121,2941,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 908 . T <*> 0 . DP=5;I16=3,2,0,0,194,7554,0,0,300,18000,0,0,120,2900,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 909 . T <*> 0 . DP=5;I16=3,2,0,0,185,6915,0,0,300,18000,0,0,118,2812,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 910 . A <*> 0 . DP=5;I16=3,2,0,0,187,7029,0,0,300,18000,0,0,116,2728,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 911 . A <*> 0 . DP=5;I16=3,2,0,0,193,7491,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 912 . A <*> 0 . DP=5;I16=3,2,0,0,200,8024,0,0,300,18000,0,0,112,2572,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 913 . A <*> 0 . DP=5;I16=3,2,0,0,197,7807,0,0,300,18000,0,0,110,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 914 . A <*> 0 . DP=5;I16=3,2,0,0,190,7228,0,0,300,18000,0,0,108,2432,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 915 . T <*> 0 . DP=5;I16=3,2,0,0,189,7159,0,0,300,18000,0,0,106,2368,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 916 . T <*> 0 . DP=5;I16=3,2,0,0,189,7169,0,0,300,18000,0,0,103,2259,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 917 . A <*> 0 . DP=5;I16=3,2,0,0,197,7783,0,0,300,18000,0,0,100,2156,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 918 . G <*> 0 . DP=5;I16=3,2,0,0,170,5848,0,0,300,18000,0,0,97,2059,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 919 . C <*> 0 . DP=5;I16=3,2,0,0,175,6487,0,0,300,18000,0,0,94,1968,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 920 . T <*> 0 . DP=5;I16=3,2,0,0,197,7805,0,0,300,18000,0,0,91,1883,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 921 . G <*> 0 . DP=5;I16=3,2,0,0,188,7080,0,0,300,18000,0,0,87,1755,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 922 . G <*> 0 . DP=5;I16=3,2,0,0,175,6227,0,0,300,18000,0,0,83,1635,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 923 . G <*> 0 . DP=5;I16=3,2,0,0,165,5515,0,0,300,18000,0,0,79,1523,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 924 . C <*> 0 . DP=5;I16=3,2,0,0,181,6579,0,0,300,18000,0,0,75,1419,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 925 . A <*> 0 . DP=5;I16=3,2,0,0,187,7067,0,0,300,18000,0,0,71,1323,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 926 . T <*> 0 . DP=5;I16=3,2,0,0,186,6994,0,0,300,18000,0,0,67,1235,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 927 . G <*> 0 . DP=5;I16=3,2,0,0,182,6682,0,0,300,18000,0,0,63,1155,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 928 . G <*> 0 . DP=5;I16=3,2,0,0,173,6013,0,0,300,18000,0,0,59,1083,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 929 . T <*> 0 . DP=4;I16=3,1,0,0,146,5362,0,0,240,14400,0,0,56,1018,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 930 . G <*> 0 . DP=4;I16=3,1,0,0,145,5287,0,0,240,14400,0,0,53,959,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 931 . G <*> 0 . DP=4;I16=3,1,0,0,129,4185,0,0,240,14400,0,0,50,906,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 932 . T <*> 0 . DP=4;I16=3,1,0,0,139,4863,0,0,240,14400,0,0,47,859,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 933 . G <*> 0 . DP=4;I16=3,1,0,0,131,4299,0,0,240,14400,0,0,43,769,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 934 . C <*> 0 . DP=3;I16=3,0,0,0,119,4721,0,0,180,10800,0,0,40,686,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 935 . A <*> 0 . DP=3;I16=3,0,0,0,121,4881,0,0,180,10800,0,0,37,609,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 936 . T <*> 0 . DP=3;I16=3,0,0,0,120,4800,0,0,180,10800,0,0,34,538,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 937 . G <*> 0 . DP=4;I16=4,0,0,0,149,5589,0,0,240,14400,0,0,31,473,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 938 . C <*> 0 . DP=4;I16=4,0,0,0,155,6013,0,0,240,14400,0,0,29,415,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 939 . C <*> 0 . DP=4;I16=4,0,0,0,150,5634,0,0,240,14400,0,0,27,365,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 940 . T <*> 0 . DP=4;I16=4,0,0,0,163,6657,0,0,240,14400,0,0,25,323,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 941 . G <*> 0 . DP=3;I16=3,0,0,0,111,4113,0,0,180,10800,0,0,24,288,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 942 . T <*> 0 . DP=3;I16=3,0,0,0,112,4194,0,0,180,10800,0,0,23,259,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 943 . A <*> 0 . DP=3;I16=3,0,0,0,111,4133,0,0,180,10800,0,0,22,236,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 944 . G <*> 0 . DP=3;I16=3,0,0,0,114,4338,0,0,180,10800,0,0,21,219,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 945 . T <*> 0 . DP=3;I16=3,0,0,0,114,4346,0,0,180,10800,0,0,20,208,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 946 . C <*> 0 . DP=2;I16=2,0,0,0,76,2938,0,0,120,7200,0,0,20,202,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 947 . C <*> 0 . DP=2;I16=2,0,0,0,72,2624,0,0,120,7200,0,0,20,200,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 948 . C <*> 0 . DP=2;I16=2,0,0,0,76,2890,0,0,120,7200,0,0,20,202,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 949 . A <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,120,7200,0,0,20,208,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 950 . G <*> 0 . DP=2;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,20,218,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 951 . C <*> 0 . DP=2;I16=2,0,0,0,80,3200,0,0,120,7200,0,0,20,232,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 952 . T <*> 0 . DP=2;I16=2,0,0,0,80,3218,0,0,120,7200,0,0,20,250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 953 . A <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,20,272,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 954 . T <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,20,298,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 955 . T <*> 0 . DP=2;I16=2,0,0,0,75,2813,0,0,120,7200,0,0,20,328,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 956 . C <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,120,7200,0,0,20,362,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 957 . A <*> 0 . DP=2;I16=2,0,0,0,74,2746,0,0,120,7200,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 958 . C <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 959 . A <*> 0 . DP=1;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 960 . G <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 961 . T <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 962 . G <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 963 . C <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 964 . T <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 965 . G <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 966 . A <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 967 . G <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 968 . G <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 969 . T <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 17 970 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 17 971 . G <*> 0 . DP=1;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 972 . G <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 973 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 974 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 975 . G <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 976 . A <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 977 . T <*> 0 . DP=1;I16=1,0,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 978 . G <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 979 . C <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 980 . T <*> 0 . DP=1;I16=1,0,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 17 981 . T <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 982 . G <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 983 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 984 . G <*> 0 . DP=1;I16=1,0,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 17 985 . C <*> 0 . DP=2;I16=1,1,0,0,65,2137,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 986 . C <*> 0 . DP=2;I16=1,1,0,0,69,2493,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 987 . C <*> 0 . DP=2;I16=1,1,0,0,70,2458,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 988 . A <*> 0 . DP=2;I16=1,1,0,0,82,3362,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQ0F=0 PL 0,6,82 17 989 . G <*> 0 . DP=2;I16=1,1,0,0,80,3208,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 990 . G <*> 0 . DP=2;I16=1,1,0,0,83,3457,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQ0F=0 PL 0,6,83 17 991 . A <*> 0 . DP=2;I16=1,1,0,0,80,3218,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 992 . G <*> 0 . DP=2;I16=1,1,0,0,76,2906,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQ0F=0 PL 0,6,76 17 993 . T <*> 0 . DP=2;I16=1,1,0,0,73,2725,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 994 . T <*> 0 . DP=3;I16=2,1,0,0,109,3995,0,0,180,10800,0,0,34,706,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 995 . C <*> 0 . DP=3;I16=2,1,0,0,117,4571,0,0,180,10800,0,0,36,726,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 996 . A <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,38,750,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 997 . A <*> 0 . DP=3;I16=2,1,0,0,128,5472,0,0,180,10800,0,0,40,778,0,0;QS=1,0;MQ0F=0 PL 0,9,121 17 998 . G <*> 0 . DP=3;I16=2,1,0,0,122,4980,0,0,180,10800,0,0,42,810,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 999 . G <*> 0 . DP=3;I16=2,1,0,0,118,4650,0,0,180,10800,0,0,44,846,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 1000 . C <*> 0 . DP=3;I16=2,1,0,0,116,4490,0,0,180,10800,0,0,46,886,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1001 . T <*> 0 . DP=3;I16=2,1,0,0,129,5555,0,0,180,10800,0,0,48,930,0,0;QS=1,0;MQ0F=0 PL 0,9,122 17 1002 . G <*> 0 . DP=3;I16=2,1,0,0,115,4459,0,0,180,10800,0,0,50,978,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1003 . C <*> 0 . DP=3;I16=2,1,0,0,108,4046,0,0,180,10800,0,0,52,1030,0,0;QS=1,0;MQ0F=0 PL 0,9,102 17 1004 . A <*> 0 . DP=3;I16=2,1,0,0,104,3706,0,0,180,10800,0,0,54,1086,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 1005 . A <*> 0 . DP=3;I16=2,1,0,0,120,4856,0,0,180,10800,0,0,56,1146,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1006 . T <*> 0 . DP=3;I16=2,1,0,0,122,4964,0,0,180,10800,0,0,58,1210,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1007 . G <*> 0 . DP=3;I16=2,1,0,0,120,4802,0,0,180,10800,0,0,60,1278,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1008 . A <*> 0 . DP=3;I16=2,1,0,0,126,5294,0,0,180,10800,0,0,62,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,118 17 1009 . G <*> 0 . DP=3;I16=2,1,0,0,123,5049,0,0,180,10800,0,0,64,1426,0,0;QS=1,0;MQ0F=0 PL 0,9,116 17 1010 . C <*> 0 . DP=3;I16=2,1,0,0,121,4889,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1011 . T <*> 0 . DP=3;I16=2,1,0,0,125,5249,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,118 17 1012 . A <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1013 . T <*> 0 . DP=3;I16=2,1,0,0,122,4964,0,0,180,10800,0,0,68,1562,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1014 . G <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,68,1554,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1015 . A <*> 0 . DP=3;I16=2,1,0,0,116,4600,0,0,180,10800,0,0,68,1550,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1016 . T <*> 0 . DP=3;I16=2,1,0,0,108,4074,0,0,180,10800,0,0,68,1550,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 1017 . T <*> 0 . DP=3;I16=2,1,0,0,112,4312,0,0,180,10800,0,0,68,1554,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 1018 . G <*> 0 . DP=3;I16=2,1,0,0,97,3445,0,0,180,10800,0,0,68,1562,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 1019 . C <*> 0 . DP=3;I16=2,1,0,0,111,4289,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 1020 . G <*> 0 . DP=3;I16=2,1,0,0,92,2832,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,87 17 1021 . C <*> 0 . DP=3;I16=2,1,0,0,99,3653,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,92 17 1022 . C <*> 0 . DP=3;I16=2,1,0,0,116,4526,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1023 . A <*> 0 . DP=3;I16=2,1,0,0,119,4731,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1024 . C <*> 0 . DP=3;I16=2,1,0,0,112,4214,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1025 . T <*> 0 . DP=3;I16=2,1,0,0,124,5142,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 1026 . G <*> 0 . DP=3;I16=2,1,0,0,120,4802,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1027 . C <*> 0 . DP=3;I16=2,1,0,0,117,4589,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1028 . A <*> 0 . DP=3;I16=2,1,0,0,106,3906,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 1029 . C <*> 0 . DP=3;I16=2,1,0,0,118,4646,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 1030 . T <*> 0 . DP=3;I16=2,1,0,0,130,5634,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,122 17 1031 . T <*> 0 . DP=3;I16=2,1,0,0,120,4824,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1032 . T <*> 0 . DP=3;I16=2,1,0,0,118,4660,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 1033 . G <*> 0 . DP=3;I16=2,1,0,0,107,3969,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 1034 . G <*> 0 . DP=3;I16=2,1,0,0,108,3938,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,102 17 1035 . C <*> 0 . DP=3;I16=2,1,0,0,100,3654,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 1036 . C <*> 0 . DP=4;I16=3,1,0,0,153,5921,0,0,240,14400,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 1037 . T <*> 0 . DP=4;I16=3,1,0,0,161,6505,0,0,240,14400,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 1038 . G <*> 0 . DP=3;I16=2,1,0,0,114,4346,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1039 . G <*> 0 . DP=3;I16=2,1,0,0,117,4625,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 1040 . A <*> 0 . DP=3;I16=2,1,0,0,113,4317,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1041 . C <*> 0 . DP=3;I16=2,1,0,0,116,4520,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1042 . A <*> 0 . DP=5;I16=4,1,0,0,178,6394,0,0,300,18000,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 1043 . A <*> 0 . DP=5;I16=4,1,0,0,201,8109,0,0,300,18000,0,0,59,1301,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 1044 . C <*> 0 . DP=5;I16=4,1,0,0,185,6881,0,0,300,18000,0,0,62,1322,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 1045 . A <*> 0 . DP=5;I16=4,1,0,0,191,7341,0,0,300,18000,0,0,65,1349,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 1046 . G <*> 0 . DP=5;I16=4,1,0,0,194,7580,0,0,300,18000,0,0,68,1382,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1047 . A <*> 0 . DP=5;I16=4,1,0,0,204,8334,0,0,300,18000,0,0,71,1421,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1048 . G <*> 0 . DP=5;I16=4,1,0,0,191,7339,0,0,300,18000,0,0,74,1466,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 1049 . C <*> 0 . DP=5;I16=4,1,0,0,198,7856,0,0,300,18000,0,0,77,1517,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 1050 . A <*> 0 . DP=5;I16=4,1,0,0,169,6371,0,0,300,18000,0,0,80,1574,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 1051 . A <*> 0 . DP=5;I16=4,1,0,0,182,6962,0,0,300,18000,0,0,83,1637,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 1052 . A <*> 0 . DP=5;I16=4,1,0,0,185,7123,0,0,300,18000,0,0,86,1706,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 1053 . A <*> 0 . DP=5;I16=4,1,0,0,186,7442,0,0,300,18000,0,0,89,1781,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 1054 . C <*> 0 . DP=5;I16=4,1,0,0,187,7033,0,0,300,18000,0,0,92,1862,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 1055 . C <*> 0 . DP=5;I16=4,1,0,0,191,7375,0,0,300,18000,0,0,95,1949,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 1056 . C <*> 0 . DP=5;I16=4,1,0,0,198,7986,0,0,300,18000,0,0,98,2042,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 1057 . T <*> 0 . DP=5;I16=4,1,0,0,197,7989,0,0,300,18000,0,0,101,2141,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 1058 . G <*> 0 . DP=5;I16=4,1,0,0,190,7328,0,0,300,18000,0,0,104,2246,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 1059 . T <*> 0 . DP=5;I16=4,1,0,0,185,6901,0,0,300,18000,0,0,107,2357,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 1060 . C <*> 0 . DP=5;I16=4,1,0,0,198,7862,0,0,300,18000,0,0,110,2474,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 1061 . T <*> 0 . DP=5;I16=4,1,0,0,193,7643,0,0,300,18000,0,0,112,2548,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1062 . C <*> 0 . DP=5;I16=4,1,0,0,201,8099,0,0,300,18000,0,0,113,2579,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 1063 . T <*> 0 . DP=5;I16=4,1,0,0,204,8428,0,0,300,18000,0,0,114,2616,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 1064 . A <*> 0 . DP=5;I16=4,1,0,0,201,8085,0,0,300,18000,0,0,115,2659,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 1065 . A <*> 0 . DP=5;I16=4,1,0,0,212,9010,0,0,300,18000,0,0,116,2708,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 1066 . A <*> 0 . DP=6;I16=5,1,0,0,244,10022,0,0,360,21600,0,0,117,2763,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 1067 . A <*> 0 . DP=6;I16=5,1,0,0,250,10460,0,0,360,21600,0,0,119,2825,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 1068 . A <*> 0 . DP=6;I16=5,1,0,0,250,10460,0,0,360,21600,0,0,119,2793,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 1069 . A <*> 0 . DP=7;I16=6,1,0,0,264,10118,0,0,420,25200,0,0,119,2765,0,0;QS=1,0;MQ0F=0 PL 0,21,189 17 1070 . A <*> 0 . DP=7;I16=6,1,0,0,281,11317,0,0,420,25200,0,0,119,2693,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 1071 . G <*> 0 . DP=7;I16=6,1,0,0,274,10748,0,0,420,25200,0,0,119,2629,0,0;QS=1,0;MQ0F=0 PL 0,21,191 17 1072 . A <*> 0 . DP=7;I16=6,1,0,0,276,10932,0,0,420,25200,0,0,119,2573,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 1073 . A <*> 0 . DP=7;I16=6,1,0,0,283,11473,0,0,420,25200,0,0,119,2525,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 1074 . A <*> 0 . DP=7;I16=6,1,0,0,287,11811,0,0,420,25200,0,0,119,2485,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 1075 . A <*> 0 . DP=7;I16=6,1,0,0,282,11444,0,0,420,25200,0,0,119,2453,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 1076 . G <*> 0 . DP=7;I16=6,1,0,0,261,9981,0,0,420,25200,0,0,119,2429,0,0;QS=1,0;MQ0F=0 PL 0,21,183 17 1077 . A <*> 0 . DP=8;I16=7,1,0,0,318,12728,0,0,480,28800,0,0,119,2413,0,0;QS=1,0;MQ0F=0 PL 0,24,210 17 1078 . A <*> 0 . DP=8;I16=7,1,0,0,328,13500,0,0,480,28800,0,0,120,2406,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 1079 . A <*> 0 . DP=8;I16=7,1,0,0,317,12637,0,0,480,28800,0,0,121,2409,0,0;QS=1,0;MQ0F=0 PL 0,24,210 17 1080 . A <*> 0 . DP=8;I16=7,1,0,0,333,13899,0,0,480,28800,0,0,122,2422,0,0;QS=1,0;MQ0F=0 PL 0,24,219 17 1081 . G <*> 0 . DP=9;I16=8,1,0,0,342,13060,0,0,540,32400,0,0,123,2445,0,0;QS=1,0;MQ0F=0 PL 0,27,210 17 1082 . A <*> 0 . DP=9;I16=8,1,0,0,357,14271,0,0,540,32400,0,0,125,2479,0,0;QS=1,0;MQ0F=0 PL 0,27,220 17 1083 . A <*> 0 . DP=9;I16=8,1,0,0,356,14290,0,0,540,32400,0,0,127,2525,0,0;QS=1,0;MQ0F=0 PL 0,27,219 17 1084 . A <*> 0 . DP=9;I16=8,1,0,0,354,14138,0,0,540,32400,0,0,129,2583,0,0;QS=1,0;MQ0F=0 PL 0,27,218 17 1085 . A <*> 0 . DP=9;I16=8,1,0,0,354,14182,0,0,540,32400,0,0,131,2653,0,0;QS=1,0;MQ0F=0 PL 0,27,219 17 1086 . A <*> 0 . DP=8;I16=8,0,0,0,309,12149,0,0,480,28800,0,0,134,2734,0,0;QS=1,0;MQ0F=0 PL 0,24,179 17 1087 . C <*> 0 . DP=9;I16=9,0,0,0,319,11641,0,0,540,32400,0,0,137,2825,0,0;QS=1,0;MQ0F=0 PL 0,27,173 17 1088 . T <*> 0 . DP=9;I16=9,0,0,0,378,15920,0,0,540,32400,0,0,141,2927,0,0;QS=1,0;MQ0F=0 PL 0,27,198 17 1089 . C <*> 0 . DP=9;I16=9,0,0,0,351,13905,0,0,540,32400,0,0,145,3041,0,0;QS=1,0;MQ0F=0 PL 0,27,188 17 1090 . A <*> 0 . DP=9;I16=9,0,0,0,348,13530,0,0,540,32400,0,0,149,3167,0,0;QS=1,0;MQ0F=0 PL 0,27,183 17 1091 . C <*> 0 . DP=9;I16=9,0,0,0,333,12443,0,0,540,32400,0,0,153,3305,0,0;QS=1,0;MQ0F=0 PL 0,27,177 17 1092 . T <*> 0 . DP=9;I16=9,0,0,0,378,15912,0,0,540,32400,0,0,156,3404,0,0;QS=1,0;MQ0F=0 PL 0,27,198 17 1093 . G <*> 0 . DP=9;I16=9,0,0,0,348,13536,0,0,540,32400,0,0,159,3513,0,0;QS=1,0;MQ0F=0 PL 0,27,184 17 1094 . G T,<*> 0 . DP=9;I16=8,0,1,0,326,13362,12,144,480,28800,60,3600,155,3583,7,49;QS=0.964497,0.035503,0;SGB=-0.379885;RPBZ=-1.55569;MQBZ=0;BQBZ=-1.56227;SCBZ=0;MQ0F=0 PL 0,14,177,24,180,181 17 1095 . A <*> 0 . DP=8;I16=8,0,0,0,310,12292,0,0,480,28800,0,0,165,3709,0,0;QS=1,0;MQ0F=0 PL 0,24,178 17 1096 . T <*> 0 . DP=9;I16=9,0,0,0,331,12443,0,0,540,32400,0,0,168,3792,0,0;QS=1,0;MQ0F=0 PL 0,27,178 17 1097 . A <*> 0 . DP=9;I16=9,0,0,0,330,12450,0,0,540,32400,0,0,172,3882,0,0;QS=1,0;MQ0F=0 PL 0,27,177 17 1098 . T <*> 0 . DP=9;I16=9,0,0,0,356,14108,0,0,540,32400,0,0,176,3980,0,0;QS=1,0;MQ0F=0 PL 0,27,186 17 1099 . G <*> 0 . DP=9;I16=9,0,0,0,346,13384,0,0,540,32400,0,0,180,4086,0,0;QS=1,0;MQ0F=0 PL 0,27,182 17 1100 . A <*> 0 . DP=9;I16=9,0,0,0,363,14713,0,0,540,32400,0,0,184,4200,0,0;QS=1,0;MQ0F=0 PL 0,27,191 17 1101 . A <*> 0 . DP=9;I16=9,0,0,0,377,15835,0,0,540,32400,0,0,188,4322,0,0;QS=1,0;MQ0F=0 PL 0,27,198 17 1102 . T <*> 0 . DP=9;I16=9,0,0,0,356,14128,0,0,540,32400,0,0,192,4452,0,0;QS=1,0;MQ0F=0 PL 0,27,186 17 1103 . G <*> 0 . DP=10;I16=9,1,0,0,384,14810,0,0,600,36000,0,0,195,4539,0,0;QS=1,0;MQ0F=0 PL 0,30,222 17 1104 . A <*> 0 . DP=10;I16=9,1,0,0,405,16479,0,0,600,36000,0,0,199,4633,0,0;QS=1,0;MQ0F=0 PL 0,30,233 17 1105 . T <*> 0 . DP=10;I16=9,1,0,0,389,15179,0,0,600,36000,0,0,203,4735,0,0;QS=1,0;MQ0F=0 PL 0,30,222 17 1106 . A <*> 0 . DP=10;I16=9,1,0,0,380,14516,0,0,600,36000,0,0,207,4845,0,0;QS=1,0;MQ0F=0 PL 0,30,217 17 1107 . C <*> 0 . DP=10;I16=9,1,0,0,385,14881,0,0,600,36000,0,0,210,4912,0,0;QS=1,0;MQ0F=0 PL 0,30,220 17 1108 . A <*> 0 . DP=10;I16=9,1,0,0,400,16056,0,0,600,36000,0,0,213,4985,0,0;QS=1,0;MQ0F=0 PL 0,30,227 17 1109 . G <*> 0 . DP=10;I16=9,1,0,0,390,15304,0,0,600,36000,0,0,216,5064,0,0;QS=1,0;MQ0F=0 PL 0,30,224 17 1110 . G <*> 0 . DP=10;I16=9,1,0,0,389,15219,0,0,600,36000,0,0,219,5149,0,0;QS=1,0;MQ0F=0 PL 0,30,224 17 1111 . T <*> 0 . DP=10;I16=9,1,0,0,371,13881,0,0,600,36000,0,0,222,5240,0,0;QS=1,0;MQ0F=0 PL 0,30,211 17 1112 . T <*> 0 . DP=10;I16=9,1,0,0,394,15542,0,0,600,36000,0,0,224,5288,0,0;QS=1,0;MQ0F=0 PL 0,30,221 17 1113 . G <*> 0 . DP=11;I16=10,1,0,0,418,15980,0,0,660,39600,0,0,225,5293,0,0;QS=1,0;MQ0F=0 PL 0,33,222 17 1114 . A <*> 0 . DP=11;I16=10,1,0,0,444,18090,0,0,660,39600,0,0,227,5305,0,0;QS=1,0;MQ0F=0 PL 0,33,238 17 1115 . G <*> 0 . DP=11;I16=10,1,0,0,442,17812,0,0,660,39600,0,0,229,5325,0,0;QS=1,0;MQ0F=0 PL 0,33,234 17 1116 . G <*> 0 . DP=11;I16=10,1,0,0,415,15869,0,0,660,39600,0,0,231,5353,0,0;QS=1,0;MQ0F=0 PL 0,33,226 17 1117 . A <*> 0 . DP=11;I16=10,1,0,0,430,17002,0,0,660,39600,0,0,233,5389,0,0;QS=1,0;MQ0F=0 PL 0,33,231 17 1118 . T <*> 0 . DP=12;I16=9,2,0,0,455,19227,0,0,660,39600,0,0,209,4759,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1119 . C <*> 0 . DP=12;I16=9,2,0,0,466,20132,0,0,660,39600,0,0,211,4765,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1120 . C <*> 0 . DP=12;I16=9,2,0,0,463,19943,0,0,660,39600,0,0,213,4783,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1121 . A <*> 0 . DP=13;I16=10,2,0,0,498,21106,0,0,720,43200,0,0,215,4813,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1122 . T <*> 0 . DP=13;I16=10,2,0,0,499,21179,0,0,720,43200,0,0,217,4805,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1123 . T <*> 0 . DP=13;I16=10,2,0,0,500,21294,0,0,720,43200,0,0,219,4809,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1124 . A <*> 0 . DP=13;I16=10,2,0,0,494,20762,0,0,720,43200,0,0,221,4825,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1125 . T <*> 0 . DP=13;I16=10,2,0,0,504,21564,0,0,720,43200,0,0,223,4853,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1126 . C <*> 0 . DP=13;I16=10,2,0,0,507,21851,0,0,720,43200,0,0,225,4893,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1127 . T <*> 0 . DP=13;I16=10,2,0,0,513,22447,0,0,720,43200,0,0,227,4945,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1128 . G <*> 0 . DP=13;I16=10,2,0,0,501,21369,0,0,720,43200,0,0,229,5009,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1129 . A G,<*> 0 . DP=13;I16=10,1,0,1,463,19969,32,1024,660,39600,60,3600,205,4409,25,625;QS=0.935354,0.0646465,0;SGB=-0.379885;RPBZ=-0.724207;MQBZ=0;MQSBZ=0;BQBZ=-1.31512;SCBZ=0;MQ0F=0 PL 0,4,230,33,233,251 17 1130 . A <*> 0 . DP=13;I16=10,2,0,0,506,21796,0,0,720,43200,0,0,231,5069,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1131 . A <*> 0 . DP=13;I16=10,2,0,0,502,21496,0,0,720,43200,0,0,232,5114,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1132 . T <*> 0 . DP=13;I16=10,2,0,0,499,21159,0,0,720,43200,0,0,233,5169,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1133 . G <*> 0 . DP=13;I16=10,2,0,0,504,21546,0,0,720,43200,0,0,234,5234,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1134 . C <*> 0 . DP=13;I16=10,2,0,0,516,22556,0,0,720,43200,0,0,235,5309,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1135 . T <*> 0 . DP=13;I16=10,2,0,0,539,24493,0,0,720,43200,0,0,236,5394,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1136 . T <*> 0 . DP=13;I16=10,2,0,0,497,21161,0,0,720,43200,0,0,237,5489,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1137 . G <*> 0 . DP=12;I16=9,2,0,0,461,19745,0,0,660,39600,0,0,239,5593,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1138 . G <*> 0 . DP=12;I16=9,2,0,0,440,18182,0,0,660,39600,0,0,241,5705,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1139 . A <*> 0 . DP=12;I16=9,2,0,0,468,20350,0,0,660,39600,0,0,242,5774,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1140 . C <*> 0 . DP=12;I16=9,2,0,0,450,18922,0,0,660,39600,0,0,243,5849,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1141 . C <*> 0 . DP=12;I16=9,2,0,0,470,20464,0,0,660,39600,0,0,244,5930,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1142 . A <*> 0 . DP=12;I16=9,2,0,0,451,19059,0,0,660,39600,0,0,244,5968,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1143 . G <*> 0 . DP=10;I16=8,2,0,0,401,16179,0,0,600,36000,0,0,245,6013,0,0;QS=1,0;MQ0F=0 PL 0,30,253 17 1144 . A <*> 0 . DP=10;I16=8,2,0,0,400,16170,0,0,600,36000,0,0,245,6013,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1145 . T <*> 0 . DP=10;I16=8,2,0,0,394,15618,0,0,600,36000,0,0,244,5968,0,0;QS=1,0;MQ0F=0 PL 0,30,249 17 1146 . G <*> 0 . DP=10;I16=8,2,0,0,400,16058,0,0,600,36000,0,0,243,5929,0,0;QS=1,0;MQ0F=0 PL 0,30,254 17 1147 . T <*> 0 . DP=10;I16=8,2,0,0,397,16013,0,0,600,36000,0,0,241,5845,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1148 . T <*> 0 . DP=10;I16=8,2,0,0,404,16434,0,0,600,36000,0,0,239,5765,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1149 . T <*> 0 . DP=10;I16=8,2,0,0,417,17443,0,0,600,36000,0,0,237,5689,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1150 . T <*> 0 . DP=10;I16=8,2,0,0,412,17020,0,0,600,36000,0,0,235,5617,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1151 . G <*> 0 . DP=10;I16=8,2,0,0,393,15523,0,0,600,36000,0,0,233,5549,0,0;QS=1,0;MQ0F=0 PL 0,30,248 17 1152 . A <*> 0 . DP=11;I16=8,3,0,0,441,18063,0,0,660,39600,0,0,231,5485,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1153 . A <*> 0 . DP=11;I16=8,3,0,0,438,17700,0,0,660,39600,0,0,229,5377,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1154 . T <*> 0 . DP=11;I16=8,3,0,0,434,17352,0,0,660,39600,0,0,227,5277,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1155 . T <*> 0 . DP=11;I16=8,3,0,0,450,18518,0,0,660,39600,0,0,225,5185,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1156 . T <*> 0 . DP=11;I16=8,3,0,0,454,18846,0,0,660,39600,0,0,223,5101,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1157 . T <*> 0 . DP=11;I16=8,3,0,0,455,18851,0,0,660,39600,0,0,220,4976,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1158 . G <*> 0 . DP=11;I16=8,3,0,0,456,18954,0,0,660,39600,0,0,217,4861,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1159 . G <*> 0 . DP=11;I16=8,3,0,0,432,17154,0,0,660,39600,0,0,214,4756,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1160 . A <*> 0 . DP=13;I16=8,5,0,0,490,18826,0,0,780,46800,0,0,211,4661,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1161 . T <*> 0 . DP=13;I16=8,5,0,0,510,20188,0,0,780,46800,0,0,210,4578,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1162 . T <*> 0 . DP=13;I16=8,5,0,0,510,20196,0,0,780,46800,0,0,209,4509,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1163 . T <*> 0 . DP=13;I16=8,5,0,0,520,20934,0,0,780,46800,0,0,207,4405,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1164 . T <*> 0 . DP=13;I16=8,5,0,0,522,21092,0,0,780,46800,0,0,205,4317,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1165 . T <*> 0 . DP=13;I16=8,5,0,0,539,22453,0,0,780,46800,0,0,203,4245,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1166 . T <*> 0 . DP=13;I16=8,5,0,0,515,20565,0,0,780,46800,0,0,201,4189,0,0;QS=1,0;MQ0F=0 PL 0,39,255 17 1167 . C <*> 0 . DP=12;I16=7,5,0,0,479,19261,0,0,720,43200,0,0,200,4148,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1168 . A <*> 0 . DP=12;I16=7,5,0,0,482,19408,0,0,720,43200,0,0,199,4121,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1169 . T <*> 0 . DP=12;I16=7,5,0,0,475,18881,0,0,720,43200,0,0,198,4108,0,0;QS=1,0;MQ0F=0 PL 0,36,255 17 1170 . A <*> 0 . DP=11;I16=6,5,0,0,421,16377,0,0,660,39600,0,0,198,4108,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1171 . T <*> 0 . DP=11;I16=6,5,0,0,437,17453,0,0,660,39600,0,0,198,4120,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1172 . T <*> 0 . DP=11;I16=6,5,0,0,451,18549,0,0,660,39600,0,0,197,4095,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1173 . T <*> 0 . DP=11;I16=6,5,0,0,449,18407,0,0,660,39600,0,0,196,4084,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1174 . T <*> 0 . DP=11;I16=6,5,0,0,443,17907,0,0,660,39600,0,0,195,4087,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1175 . G <*> 0 . DP=11;I16=6,5,0,0,411,15559,0,0,660,39600,0,0,194,4104,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1176 . T <*> 0 . DP=11;I16=6,5,0,0,406,15662,0,0,660,39600,0,0,193,4135,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1177 . A <*> 0 . DP=11;I16=6,5,0,0,418,16050,0,0,660,39600,0,0,192,4180,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1178 . A <*> 0 . DP=10;I16=5,5,0,0,387,15163,0,0,600,36000,0,0,191,4187,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1179 . T <*> 0 . DP=10;I16=5,5,0,0,391,15435,0,0,600,36000,0,0,189,4155,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1180 . C <*> 0 . DP=10;I16=5,5,0,0,402,16274,0,0,600,36000,0,0,187,4135,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1181 . T <*> 0 . DP=10;I16=5,5,0,0,407,16683,0,0,600,36000,0,0,185,4127,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1182 . T <*> 0 . DP=9;I16=4,5,0,0,351,13901,0,0,540,32400,0,0,184,4130,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1183 . T <*> 0 . DP=9;I16=4,5,0,0,341,13579,0,0,540,32400,0,0,183,4143,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1184 . G <*> 0 . DP=9;I16=4,5,0,0,354,13996,0,0,540,32400,0,0,182,4166,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1185 . C <*> 0 . DP=9;I16=4,5,0,0,341,12959,0,0,540,32400,0,0,181,4199,0,0;QS=1,0;MQ0F=0 PL 0,27,250 17 1186 . A <*> 0 . DP=9;I16=4,5,0,0,370,15280,0,0,540,32400,0,0,178,4140,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1187 . G <*> 0 . DP=9;I16=4,5,0,0,320,11816,0,0,540,32400,0,0,175,4087,0,0;QS=1,0;MQ0F=0 PL 0,27,240 17 1188 . T <*> 0 . DP=8;I16=3,5,0,0,282,10330,0,0,480,28800,0,0,173,4039,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 1189 . A <*> 0 . DP=9;I16=4,5,0,0,342,13108,0,0,540,32400,0,0,170,3946,0,0;QS=1,0;MQ0F=0 PL 0,27,252 17 1190 . T <*> 0 . DP=9;I16=4,5,0,0,341,13061,0,0,540,32400,0,0,168,3860,0,0;QS=1,0;MQ0F=0 PL 0,27,252 17 1191 . A <*> 0 . DP=9;I16=4,5,0,0,330,12352,0,0,540,32400,0,0,166,3782,0,0;QS=1,0;MQ0F=0 PL 0,27,245 17 1192 . T <*> 0 . DP=9;I16=4,5,0,0,346,13400,0,0,540,32400,0,0,164,3712,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1193 . T <*> 0 . DP=9;I16=4,5,0,0,346,13426,0,0,540,32400,0,0,162,3650,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1194 . T <*> 0 . DP=9;I16=4,5,0,0,336,12702,0,0,540,32400,0,0,159,3547,0,0;QS=1,0;MQ0F=0 PL 0,27,249 17 1195 . A <*> 0 . DP=9;I16=4,5,0,0,313,11337,0,0,540,32400,0,0,156,3454,0,0;QS=1,0;MQ0F=0 PL 0,27,235 17 1196 . C <*> 0 . DP=9;I16=4,5,0,0,323,11653,0,0,540,32400,0,0,153,3371,0,0;QS=1,0;MQ0F=0 PL 0,27,239 17 1197 . C <*> 0 . DP=8;I16=3,5,0,0,308,11896,0,0,480,28800,0,0,150,3248,0,0;QS=1,0;MQ0F=0 PL 0,24,233 17 1198 . A <*> 0 . DP=8;I16=3,5,0,0,321,12969,0,0,480,28800,0,0,147,3135,0,0;QS=1,0;MQ0F=0 PL 0,24,245 17 1199 . G <*> 0 . DP=8;I16=3,5,0,0,290,10626,0,0,480,28800,0,0,144,3032,0,0;QS=1,0;MQ0F=0 PL 0,24,221 17 1200 . T <*> 0 . DP=8;I16=3,5,0,0,326,13324,0,0,480,28800,0,0,141,2939,0,0;QS=1,0;MQ0F=0 PL 0,24,247 17 1201 . T <*> 0 . DP=8;I16=3,5,0,0,317,12581,0,0,480,28800,0,0,138,2856,0,0;QS=1,0;MQ0F=0 PL 0,24,238 17 1202 . C <*> 0 . DP=8;I16=3,5,0,0,305,11673,0,0,480,28800,0,0,135,2783,0,0;QS=1,0;MQ0F=0 PL 0,24,230 17 1203 . A <*> 0 . DP=8;I16=3,5,0,0,316,12606,0,0,480,28800,0,0,132,2720,0,0;QS=1,0;MQ0F=0 PL 0,24,241 17 1204 . G <*> 0 . DP=7;I16=3,4,0,0,272,10668,0,0,420,25200,0,0,130,2666,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 1205 . C <*> 0 . DP=7;I16=3,4,0,0,271,10615,0,0,420,25200,0,0,128,2620,0,0;QS=1,0;MQ0F=0 PL 0,21,217 17 1206 . A <*> 0 . DP=7;I16=3,4,0,0,261,10111,0,0,420,25200,0,0,126,2582,0,0;QS=1,0;MQ0F=0 PL 0,21,212 17 1207 . T <*> 0 . DP=7;I16=3,4,0,0,241,9097,0,0,420,25200,0,0,124,2552,0,0;QS=1,0;MQ0F=0 PL 0,21,198 17 1208 . C <*> 0 . DP=7;I16=3,4,0,0,271,10567,0,0,420,25200,0,0,122,2530,0,0;QS=1,0;MQ0F=0 PL 0,21,217 17 1209 . C <*> 0 . DP=7;I16=3,4,0,0,260,9798,0,0,420,25200,0,0,120,2516,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 1210 . C <*> 0 . DP=7;I16=3,4,0,0,258,9874,0,0,420,25200,0,0,118,2510,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 1211 . T <*> 0 . DP=7;I16=3,4,0,0,264,10200,0,0,420,25200,0,0,116,2512,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 1212 . A <*> 0 . DP=7;I16=3,4,0,0,256,9428,0,0,420,25200,0,0,114,2522,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 1213 . A <*> 0 . DP=7;I16=3,4,0,0,240,8824,0,0,420,25200,0,0,112,2540,0,0;QS=1,0;MQ0F=0 PL 0,21,196 17 1214 . C <*> 0 . DP=6;I16=2,4,0,0,223,8441,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 1215 . T <*> 0 . DP=6;I16=2,4,0,0,207,7965,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 1216 . C <*> 0 . DP=6;I16=2,4,0,0,207,7455,0,0,360,21600,0,0,107,2529,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 1217 . A <*> 0 . DP=6;I16=2,4,0,0,241,9717,0,0,360,21600,0,0,105,2517,0,0;QS=1,0;MQ0F=0 PL 0,18,197 17 1218 . A <*> 0 . DP=6;I16=2,4,0,0,235,9297,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 1219 . A <*> 0 . DP=5;I16=2,3,0,0,203,8275,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,176 17 1220 . A <*> 0 . DP=5;I16=2,3,0,0,197,7847,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 1221 . A <*> 0 . DP=5;I16=2,3,0,0,186,7098,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 1222 . T <*> 0 . DP=4;I16=1,3,0,0,161,6531,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 1223 . T <*> 0 . DP=4;I16=1,3,0,0,136,5460,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 1224 . C A,<*> 0 . DP=4;I16=1,2,0,1,119,4723,8,64,180,10800,60,3600,75,1875,25,625;QS=0.937008,0.0629921,0;SGB=-0.379885;RPBZ=1.41421;MQBZ=0;MQSBZ=0;BQBZ=-1.41421;SCBZ=0;MQ0F=0 PL 0,3,103,9,106,106 17 1225 . A <*> 0 . DP=4;I16=1,3,0,0,162,6572,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 1226 . A <*> 0 . DP=4;I16=1,3,0,0,168,7058,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,147 17 1227 . A <*> 0 . DP=4;I16=1,3,0,0,167,6977,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 1228 . A <*> 0 . DP=4;I16=1,3,0,0,166,6894,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 1229 . A <*> 0 . DP=4;I16=1,3,0,0,157,6219,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 1230 . T <*> 0 . DP=4;I16=1,3,0,0,164,6734,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 1231 . C <*> 0 . DP=4;I16=1,3,0,0,157,6235,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 1232 . T <*> 0 . DP=4;I16=1,3,0,0,145,5431,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 1233 . G <*> 0 . DP=4;I16=1,3,0,0,144,5422,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 1234 . A <*> 0 . DP=4;I16=1,3,0,0,164,6736,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 1235 . A <*> 0 . DP=4;I16=1,3,0,0,159,6367,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 1236 . A <*> 0 . DP=4;I16=1,3,0,0,153,5977,0,0,240,14400,0,0,89,2033,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 1237 . T <*> 0 . DP=4;I16=1,3,0,0,152,5912,0,0,240,14400,0,0,86,1908,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 1238 . C <*> 0 . DP=4;I16=1,3,0,0,164,6758,0,0,240,14400,0,0,83,1789,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 1239 . C <*> 0 . DP=4;I16=1,3,0,0,138,5114,0,0,240,14400,0,0,80,1676,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 1240 . C <*> 0 . DP=4;I16=1,3,0,0,145,5407,0,0,240,14400,0,0,77,1569,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 1241 . A <*> 0 . DP=4;I16=1,3,0,0,160,6404,0,0,240,14400,0,0,74,1468,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 1242 . A <*> 0 . DP=5;I16=2,3,0,0,178,6622,0,0,300,18000,0,0,71,1373,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 1243 . A <*> 0 . DP=5;I16=2,3,0,0,191,7329,0,0,300,18000,0,0,69,1285,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 1244 . C <*> 0 . DP=5;I16=2,3,0,0,170,5836,0,0,300,18000,0,0,67,1205,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 1245 . G <*> 0 . DP=5;I16=2,3,0,0,182,6762,0,0,300,18000,0,0,65,1133,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1246 . C <*> 0 . DP=5;I16=2,3,0,0,168,5688,0,0,300,18000,0,0,63,1069,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 1247 . G <*> 0 . DP=5;I16=2,3,0,0,172,6070,0,0,300,18000,0,0,61,1013,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 1248 . C <*> 0 . DP=5;I16=2,3,0,0,179,6455,0,0,300,18000,0,0,59,965,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 1249 . C <*> 0 . DP=5;I16=2,3,0,0,192,7386,0,0,300,18000,0,0,57,925,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 1250 . A <*> 0 . DP=5;I16=2,3,0,0,186,6930,0,0,300,18000,0,0,55,893,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 1251 . A <*> 0 . DP=5;I16=2,3,0,0,200,8038,0,0,300,18000,0,0,53,869,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 1252 . T <*> 0 . DP=5;I16=2,3,0,0,183,6753,0,0,300,18000,0,0,51,853,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 1253 . A <*> 0 . DP=4;I16=2,2,0,0,158,6242,0,0,240,14400,0,0,50,844,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 1254 . A <*> 0 . DP=4;I16=2,2,0,0,171,7311,0,0,240,14400,0,0,49,841,0,0;QS=1,0;MQ0F=0 PL 0,12,156 17 1255 . G <*> 0 . DP=5;I16=2,3,0,0,195,7623,0,0,300,18000,0,0,48,844,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 1256 . C <*> 0 . DP=5;I16=2,3,0,0,191,7317,0,0,300,18000,0,0,48,854,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1257 . A <*> 0 . DP=5;I16=2,3,0,0,193,7457,0,0,300,18000,0,0,48,872,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 1258 . T <*> 0 . DP=5;I16=2,3,0,0,196,7692,0,0,300,18000,0,0,48,898,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 1259 . T <*> 0 . DP=5;I16=2,3,0,0,197,7765,0,0,300,18000,0,0,48,932,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 1260 . C <*> 0 . DP=5;I16=2,3,0,0,185,6911,0,0,300,18000,0,0,48,974,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 1261 . C <*> 0 . DP=3;I16=2,1,0,0,116,4502,0,0,180,10800,0,0,50,1022,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1262 . C <*> 0 . DP=3;I16=2,1,0,0,121,4893,0,0,180,10800,0,0,52,1074,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1263 . T <*> 0 . DP=3;I16=2,1,0,0,125,5219,0,0,180,10800,0,0,54,1130,0,0;QS=1,0;MQ0F=0 PL 0,9,118 17 1264 . T <*> 0 . DP=3;I16=2,1,0,0,121,4883,0,0,180,10800,0,0,56,1190,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1265 . T <*> 0 . DP=3;I16=2,1,0,0,121,4889,0,0,180,10800,0,0,57,1205,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1266 . G <*> 0 . DP=3;I16=2,1,0,0,121,4885,0,0,180,10800,0,0,58,1226,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1267 . A <*> 0 . DP=3;I16=2,1,0,0,120,4878,0,0,180,10800,0,0,59,1253,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1268 . G <*> 0 . DP=3;I16=2,1,0,0,114,4358,0,0,180,10800,0,0,59,1235,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1269 . C <*> 0 . DP=3;I16=2,1,0,0,113,4309,0,0,180,10800,0,0,59,1221,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1270 . G <*> 0 . DP=3;I16=2,1,0,0,104,3624,0,0,180,10800,0,0,59,1211,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 1271 . T <*> 0 . DP=3;I16=2,1,0,0,116,4504,0,0,180,10800,0,0,59,1205,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1272 . C <*> 0 . DP=3;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,59,1203,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1273 . A <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,59,1205,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1274 . T <*> 0 . DP=3;I16=2,1,0,0,122,4962,0,0,180,10800,0,0,59,1211,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1275 . G <*> 0 . DP=3;I16=2,1,0,0,119,4725,0,0,180,10800,0,0,59,1221,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1276 . T <*> 0 . DP=3;I16=2,1,0,0,117,4581,0,0,180,10800,0,0,59,1235,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1277 . C <*> 0 . DP=3;I16=2,1,0,0,113,4305,0,0,180,10800,0,0,59,1253,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1278 . G <*> 0 . DP=3;I16=2,1,0,0,102,3524,0,0,180,10800,0,0,59,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 1279 . G <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,59,1301,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1280 . T <*> 0 . DP=3;I16=2,1,0,0,103,3581,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 1281 . G <*> 0 . DP=3;I16=2,1,0,0,109,4009,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 1282 . C <*> 0 . DP=4;I16=2,2,0,0,143,5185,0,0,240,14400,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 1283 . T <*> 0 . DP=4;I16=2,2,0,0,168,7104,0,0,240,14400,0,0,57,1287,0,0;QS=1,0;MQ0F=0 PL 0,12,154 17 1284 . T <*> 0 . DP=4;I16=2,2,0,0,159,6341,0,0,240,14400,0,0,57,1279,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 1285 . G <*> 0 . DP=4;I16=2,2,0,0,159,6327,0,0,240,14400,0,0,57,1275,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 1286 . G <*> 0 . DP=4;I16=2,2,0,0,161,6525,0,0,240,14400,0,0,57,1275,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 1287 . A <*> 0 . DP=4;I16=2,2,0,0,149,5605,0,0,240,14400,0,0,57,1279,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 1288 . A <*> 0 . DP=4;I16=2,2,0,0,153,5895,0,0,240,14400,0,0,57,1287,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 1289 . T <*> 0 . DP=4;I16=2,2,0,0,155,6039,0,0,240,14400,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 1290 . G <*> 0 . DP=3;I16=1,2,0,0,112,4242,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1291 . T <*> 0 . DP=3;I16=1,2,0,0,124,5146,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 1292 . T <*> 0 . DP=3;I16=1,2,0,0,119,4773,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1293 . T <*> 0 . DP=3;I16=1,2,0,0,124,5126,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,116 17 1294 . G <*> 0 . DP=3;I16=1,2,0,0,126,5306,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,119 17 1295 . G <*> 0 . DP=3;I16=1,2,0,0,121,4913,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1296 . G <*> 0 . DP=3;I16=1,2,0,0,121,4899,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1297 . G <*> 0 . DP=4;I16=1,3,0,0,151,5765,0,0,240,14400,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 1298 . T <*> 0 . DP=4;I16=1,3,0,0,157,6219,0,0,240,14400,0,0,67,1507,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 1299 . T <*> 0 . DP=4;I16=1,3,0,0,154,5998,0,0,240,14400,0,0,69,1543,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 1300 . T <*> 0 . DP=4;I16=1,3,0,0,153,5915,0,0,240,14400,0,0,71,1583,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 1301 . T <*> 0 . DP=4;I16=1,3,0,0,153,5885,0,0,240,14400,0,0,73,1627,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 1302 . G <*> 0 . DP=4;I16=1,3,0,0,158,6268,0,0,240,14400,0,0,75,1675,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 1303 . G <*> 0 . DP=4;I16=1,3,0,0,156,6126,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 1304 . A <*> 0 . DP=5;I16=2,3,0,0,194,7576,0,0,300,18000,0,0,79,1783,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 1305 . T <*> 0 . DP=5;I16=2,3,0,0,199,7959,0,0,300,18000,0,0,82,1844,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 1306 . T <*> 0 . DP=5;I16=2,3,0,0,192,7426,0,0,300,18000,0,0,85,1911,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 1307 . T <*> 0 . DP=5;I16=2,3,0,0,192,7402,0,0,300,18000,0,0,88,1984,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 1308 . A <*> 0 . DP=5;I16=2,3,0,0,198,7848,0,0,300,18000,0,0,90,2012,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 1309 . C <*> 0 . DP=5;I16=2,3,0,0,194,7562,0,0,300,18000,0,0,92,2044,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 1310 . A <*> 0 . DP=5;I16=2,3,0,0,210,8856,0,0,300,18000,0,0,94,2080,0,0;QS=1,0;MQ0F=0 PL 0,15,183 17 1311 . G <*> 0 . DP=5;I16=2,3,0,0,200,8026,0,0,300,18000,0,0,96,2120,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 1312 . C <*> 0 . DP=5;I16=2,3,0,0,190,7340,0,0,300,18000,0,0,98,2164,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 1313 . T <*> 0 . DP=5;I16=2,3,0,0,201,8159,0,0,300,18000,0,0,100,2212,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 1314 . T <*> 0 . DP=5;I16=2,3,0,0,199,7973,0,0,300,18000,0,0,102,2264,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 1315 . T <*> 0 . DP=5;I16=2,3,0,0,200,8022,0,0,300,18000,0,0,104,2320,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 1316 . G <*> 0 . DP=6;I16=2,4,0,0,230,8892,0,0,360,21600,0,0,106,2380,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 1317 . G <*> 0 . DP=6;I16=2,4,0,0,223,8299,0,0,360,21600,0,0,109,2445,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 1318 . G <*> 0 . DP=6;I16=2,4,0,0,227,8609,0,0,360,21600,0,0,111,2467,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 1319 . A <*> 0 . DP=6;I16=2,4,0,0,229,8767,0,0,360,21600,0,0,113,2497,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 1320 . C <*> 0 . DP=6;I16=2,4,0,0,198,6562,0,0,360,21600,0,0,115,2535,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 1321 . G <*> 0 . DP=8;I16=2,6,0,0,289,10677,0,0,480,28800,0,0,117,2581,0,0;QS=1,0;MQ0F=0 PL 0,24,209 17 1322 . C <*> 0 . DP=8;I16=2,6,0,0,313,12275,0,0,480,28800,0,0,121,2637,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 1323 . T <*> 0 . DP=8;I16=2,6,0,0,333,13883,0,0,480,28800,0,0,124,2654,0,0;QS=1,0;MQ0F=0 PL 0,24,237 17 1324 . C <*> 0 . DP=8;I16=2,6,0,0,306,11730,0,0,480,28800,0,0,127,2681,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 1325 . A <*> 0 . DP=8;I16=2,6,0,0,304,11616,0,0,480,28800,0,0,130,2718,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 1326 . A <*> 0 . DP=8;I16=2,6,0,0,320,12836,0,0,480,28800,0,0,133,2765,0,0;QS=1,0;MQ0F=0 PL 0,24,230 17 1327 . C <*> 0 . DP=9;I16=3,6,0,0,331,12449,0,0,540,32400,0,0,136,2822,0,0;QS=1,0;MQ0F=0 PL 0,27,237 17 1328 . C <*> 0 . DP=9;I16=3,6,0,0,354,14090,0,0,540,32400,0,0,140,2890,0,0;QS=1,0;MQ0F=0 PL 0,27,254 17 1329 . T <*> 0 . DP=9;I16=3,6,0,0,363,14827,0,0,540,32400,0,0,144,2970,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1330 . G <*> 0 . DP=9;I16=3,6,0,0,337,12805,0,0,540,32400,0,0,147,3011,0,0;QS=1,0;MQ0F=0 PL 0,27,241 17 1331 . T <*> 0 . DP=9;I16=3,6,0,0,345,13287,0,0,540,32400,0,0,149,3013,0,0;QS=1,0;MQ0F=0 PL 0,27,247 17 1332 . A <*> 0 . DP=9;I16=3,6,0,0,335,12679,0,0,540,32400,0,0,151,3027,0,0;QS=1,0;MQ0F=0 PL 0,27,238 17 1333 . C <*> 0 . DP=9;I16=3,6,0,0,327,12185,0,0,540,32400,0,0,153,3053,0,0;QS=1,0;MQ0F=0 PL 0,27,236 17 1334 . C <*> 0 . DP=9;I16=3,6,0,0,332,12928,0,0,540,32400,0,0,155,3091,0,0;QS=1,0;MQ0F=0 PL 0,27,238 17 1335 . T <*> 0 . DP=9;I16=3,6,0,0,352,14130,0,0,540,32400,0,0,157,3141,0,0;QS=1,0;MQ0F=0 PL 0,27,253 17 1336 . C <*> 0 . DP=10;I16=3,7,0,0,363,13989,0,0,600,36000,0,0,159,3203,0,0;QS=1,0;MQ0F=0 PL 0,30,245 17 1337 . A <*> 0 . DP=10;I16=3,7,0,0,363,13487,0,0,600,36000,0,0,162,3278,0,0;QS=1,0;MQ0F=0 PL 0,30,247 17 1338 . A <*> 0 . DP=10;I16=3,7,0,0,395,15639,0,0,600,36000,0,0,165,3367,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1339 . T <*> 0 . DP=11;I16=3,8,0,0,408,15356,0,0,660,39600,0,0,168,3470,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1340 . A <*> 0 . DP=11;I16=3,8,0,0,400,14724,0,0,660,39600,0,0,172,3588,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1341 . A <*> 0 . DP=11;I16=3,8,0,0,400,14772,0,0,660,39600,0,0,176,3722,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1342 . A <*> 0 . DP=11;I16=3,8,0,0,381,13615,0,0,660,39600,0,0,179,3821,0,0;QS=1,0;MQ0F=0 PL 0,33,249 17 1343 . C <*> 0 . DP=10;I16=2,8,0,0,369,13821,0,0,600,36000,0,0,183,3933,0,0;QS=1,0;MQ0F=0 PL 0,30,233 17 1344 . C <*> 0 . DP=10;I16=2,8,0,0,377,14509,0,0,600,36000,0,0,187,4057,0,0;QS=1,0;MQ0F=0 PL 0,30,238 17 1345 . T <*> 0 . DP=10;I16=2,8,0,0,386,15194,0,0,600,36000,0,0,191,4193,0,0;QS=1,0;MQ0F=0 PL 0,30,242 17 1346 . G <*> 0 . DP=10;I16=2,8,0,0,380,14626,0,0,600,36000,0,0,195,4341,0,0;QS=1,0;MQ0F=0 PL 0,30,239 17 1347 . A <*> 0 . DP=10;I16=2,8,0,0,388,15314,0,0,600,36000,0,0,197,4399,0,0;QS=1,0;MQ0F=0 PL 0,30,243 17 1348 . T <*> 0 . DP=10;I16=2,8,0,0,395,15653,0,0,600,36000,0,0,199,4465,0,0;QS=1,0;MQ0F=0 PL 0,30,251 17 1349 . T <*> 0 . DP=10;I16=2,8,0,0,389,15189,0,0,600,36000,0,0,201,4539,0,0;QS=1,0;MQ0F=0 PL 0,30,248 17 1350 . T <*> 0 . DP=10;I16=2,8,0,0,392,15402,0,0,600,36000,0,0,203,4621,0,0;QS=1,0;MQ0F=0 PL 0,30,249 17 1351 . T <*> 0 . DP=10;I16=2,8,0,0,384,14782,0,0,600,36000,0,0,205,4711,0,0;QS=1,0;MQ0F=0 PL 0,30,240 17 1352 . A <*> 0 . DP=10;I16=2,8,0,0,335,11557,0,0,600,36000,0,0,207,4809,0,0;QS=1,0;MQ0F=0 PL 0,30,216 17 1353 . A <*> 0 . DP=10;I16=2,8,0,0,360,13120,0,0,600,36000,0,0,208,4864,0,0;QS=1,0;MQ0F=0 PL 0,30,230 17 1354 . A <*> 0 . DP=10;I16=2,8,0,0,360,13170,0,0,600,36000,0,0,209,4925,0,0;QS=1,0;MQ0F=0 PL 0,30,229 17 1355 . A <*> 0 . DP=10;I16=2,8,0,0,360,13130,0,0,600,36000,0,0,210,4992,0,0;QS=1,0;MQ0F=0 PL 0,30,232 17 1356 . A <*> 0 . DP=9;I16=2,7,0,0,331,12303,0,0,540,32400,0,0,212,5064,0,0;QS=1,0;MQ0F=0 PL 0,27,226 17 1357 . A <*> 0 . DP=9;I16=2,7,0,0,336,13958,0,0,540,32400,0,0,214,5140,0,0;QS=1,0;MQ0F=0 PL 0,27,222 17 1358 . G <*> 0 . DP=9;I16=2,7,0,0,289,10397,0,0,540,32400,0,0,215,5171,0,0;QS=1,0;MQ0F=0 PL 0,27,193 17 1359 . T <*> 0 . DP=9;I16=2,7,0,0,304,11432,0,0,540,32400,0,0,216,5208,0,0;QS=1,0;MQ0F=0 PL 0,27,201 17 1360 . T <*> 0 . DP=9;I16=2,7,0,0,292,10644,0,0,540,32400,0,0,217,5251,0,0;QS=1,0;MQ0F=0 PL 0,27,196 17 1361 . T <*> 0 . DP=10;I16=2,8,0,0,346,13172,0,0,600,36000,0,0,218,5300,0,0;QS=1,0;MQ0F=0 PL 0,30,212 17 1362 . G <*> 0 . DP=9;I16=1,8,0,0,340,12906,0,0,540,32400,0,0,194,4680,0,0;QS=1,0;MQ0F=0 PL 0,27,207 17 1363 . G <*> 0 . DP=9;I16=1,8,0,0,335,12505,0,0,540,32400,0,0,195,4691,0,0;QS=1,0;MQ0F=0 PL 0,27,202 17 1364 . G <*> 0 . DP=9;I16=1,8,0,0,331,12219,0,0,540,32400,0,0,196,4708,0,0;QS=1,0;MQ0F=0 PL 0,27,200 17 1365 . G <*> 0 . DP=9;I16=1,8,0,0,336,12570,0,0,540,32400,0,0,196,4680,0,0;QS=1,0;MQ0F=0 PL 0,27,202 17 1366 . G <*> 0 . DP=9;I16=1,8,0,0,332,12268,0,0,540,32400,0,0,196,4656,0,0;QS=1,0;MQ0F=0 PL 0,27,199 17 1367 . G C,<*> 0 . DP=9;I16=1,7,0,1,296,10982,27,729,480,28800,60,3600,181,4411,15,225;QS=0.916409,0.0835913,0;SGB=-0.379885;RPBZ=1.55569;MQBZ=0;MQSBZ=0;BQBZ=-1.58251;SCBZ=0;MQ0F=0 PL 0,0,171,24,174,189 17 1368 . A <*> 0 . DP=9;I16=1,8,0,0,320,11562,0,0,540,32400,0,0,196,4620,0,0;QS=1,0;MQ0F=0 PL 0,27,197 17 1369 . T <*> 0 . DP=9;I16=1,8,0,0,309,10987,0,0,540,32400,0,0,196,4608,0,0;QS=1,0;MQ0F=0 PL 0,27,194 17 1370 . T C,<*> 0 . DP=10;I16=1,8,0,1,347,13421,2,4,540,32400,60,3600,171,3975,25,625;QS=0.988604,0.011396,0;SGB=-0.379885;RPBZ=-0.873038;MQBZ=0;MQSBZ=0;BQBZ=-1.59599;SCBZ=0;MQ0F=0 PL 0,20,208,27,211,208 17 1371 . C <*> 0 . DP=10;I16=1,9,0,0,338,11742,0,0,600,36000,0,0,197,4597,0,0;QS=1,0;MQ0F=0 PL 0,30,196 17 1372 . C <*> 0 . DP=10;I16=1,9,0,0,343,12099,0,0,600,36000,0,0,198,4600,0,0;QS=1,0;MQ0F=0 PL 0,30,200 17 1373 . C <*> 0 . DP=10;I16=1,9,0,0,332,11388,0,0,600,36000,0,0,198,4560,0,0;QS=1,0;MQ0F=0 PL 0,30,195 17 1374 . C <*> 0 . DP=10;I16=1,9,0,0,374,14014,0,0,600,36000,0,0,198,4528,0,0;QS=1,0;MQ0F=0 PL 0,30,211 17 1375 . T <*> 0 . DP=10;I16=1,9,0,0,378,14378,0,0,600,36000,0,0,198,4504,0,0;QS=1,0;MQ0F=0 PL 0,30,215 17 1376 . A <*> 0 . DP=10;I16=1,9,0,0,336,11508,0,0,600,36000,0,0,198,4488,0,0;QS=1,0;MQ0F=0 PL 0,30,195 17 1377 . A <*> 0 . DP=10;I16=1,9,0,0,390,15374,0,0,600,36000,0,0,198,4480,0,0;QS=1,0;MQ0F=0 PL 0,30,228 17 1378 . G <*> 0 . DP=10;I16=1,9,0,0,336,11730,0,0,600,36000,0,0,198,4480,0,0;QS=1,0;MQ0F=0 PL 0,30,197 17 1379 . C <*> 0 . DP=10;I16=1,9,0,0,326,11052,0,0,600,36000,0,0,198,4488,0,0;QS=1,0;MQ0F=0 PL 0,30,193 17 1380 . C <*> 0 . DP=10;I16=1,9,0,0,359,13121,0,0,600,36000,0,0,197,4455,0,0;QS=1,0;MQ0F=0 PL 0,30,209 17 1381 . C <*> 0 . DP=12;I16=2,10,0,0,367,11465,0,0,720,43200,0,0,196,4432,0,0;QS=1,0;MQ0F=0 PL 0,36,208 17 1382 . G <*> 0 . DP=12;I16=2,10,0,0,425,15501,0,0,720,43200,0,0,197,4421,0,0;QS=1,0;MQ0F=0 PL 0,36,243 17 1383 . C <*> 0 . DP=11;I16=2,9,0,0,398,14630,0,0,660,39600,0,0,199,4423,0,0;QS=1,0;MQ0F=0 PL 0,33,241 17 1384 . C <*> 0 . DP=11;I16=2,9,0,0,392,14362,0,0,660,39600,0,0,201,4437,0,0;QS=1,0;MQ0F=0 PL 0,33,239 17 1385 . A C,<*> 0 . DP=11;I16=2,8,0,1,369,13727,2,4,600,36000,60,3600,179,3887,24,576;QS=0.989276,0.0107239,0;SGB=-0.379885;RPBZ=-0.633898;MQBZ=0;MQSBZ=0;BQBZ=-1.59571;SCBZ=0;MQ0F=0 PL 0,23,229,30,232,229 17 1386 . C <*> 0 . DP=11;I16=2,9,0,0,421,16205,0,0,660,39600,0,0,205,4501,0,0;QS=1,0;MQ0F=0 PL 0,33,254 17 1387 . C <*> 0 . DP=11;I16=2,9,0,0,424,16430,0,0,660,39600,0,0,206,4500,0,0;QS=1,0;MQ0F=0 PL 0,33,252 17 1388 . C <*> 0 . DP=11;I16=2,9,0,0,355,11631,0,0,660,39600,0,0,207,4509,0,0;QS=1,0;MQ0F=0 PL 0,33,211 17 1389 . G <*> 0 . DP=11;I16=2,9,0,0,423,16499,0,0,660,39600,0,0,208,4528,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1390 . G <*> 0 . DP=11;I16=2,9,0,0,441,17739,0,0,660,39600,0,0,209,4557,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1391 . A <*> 0 . DP=11;I16=2,9,0,0,467,19893,0,0,660,39600,0,0,210,4596,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1392 . G <*> 0 . DP=11;I16=2,9,0,0,436,17388,0,0,660,39600,0,0,210,4596,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1393 . A <*> 0 . DP=11;I16=2,9,0,0,440,17638,0,0,660,39600,0,0,210,4608,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1394 . C <*> 0 . DP=11;I16=2,9,0,0,427,16619,0,0,660,39600,0,0,210,4632,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1395 . A <*> 0 . DP=11;I16=2,9,0,0,471,20195,0,0,660,39600,0,0,210,4668,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1396 . G <*> 0 . DP=11;I16=2,9,0,0,448,18282,0,0,660,39600,0,0,209,4665,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 1397 . C <*> 0 . DP=11;I16=2,9,0,0,370,12542,0,0,660,39600,0,0,206,4574,0,0;QS=1,0;MQ0F=0 PL 0,33,217 17 1398 . G <*> 0 . DP=10;I16=2,8,0,0,385,15223,0,0,600,36000,0,0,204,4496,0,0;QS=1,0;MQ0F=0 PL 0,30,244 17 1399 . G <*> 0 . DP=10;I16=2,8,0,0,406,16532,0,0,600,36000,0,0,202,4430,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1400 . A <*> 0 . DP=10;I16=2,8,0,0,388,15094,0,0,600,36000,0,0,200,4376,0,0;QS=1,0;MQ0F=0 PL 0,30,246 17 1401 . T <*> 0 . DP=10;I16=2,8,0,0,421,17817,0,0,600,36000,0,0,198,4334,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1402 . T <*> 0 . DP=10;I16=2,8,0,0,411,16995,0,0,600,36000,0,0,196,4304,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1403 . T <*> 0 . DP=10;I16=2,8,0,0,408,16730,0,0,600,36000,0,0,194,4286,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 1404 . C <*> 0 . DP=10;I16=2,8,0,0,385,14971,0,0,600,36000,0,0,192,4280,0,0;QS=1,0;MQ0F=0 PL 0,30,246 17 1405 . C <*> 0 . DP=9;I16=1,8,0,0,368,15080,0,0,540,32400,0,0,191,4285,0,0;QS=1,0;MQ0F=0 PL 0,27,229 17 1406 . T <*> 0 . DP=9;I16=1,8,0,0,360,14574,0,0,540,32400,0,0,190,4300,0,0;QS=1,0;MQ0F=0 PL 0,27,223 17 1407 . T <*> 0 . DP=9;I16=1,8,0,0,352,13838,0,0,540,32400,0,0,187,4223,0,0;QS=1,0;MQ0F=0 PL 0,27,215 17 1408 . A <*> 0 . DP=9;I16=1,8,0,0,381,16169,0,0,540,32400,0,0,184,4152,0,0;QS=1,0;MQ0F=0 PL 0,27,234 17 1409 . G <*> 0 . DP=9;I16=1,8,0,0,336,12600,0,0,540,32400,0,0,181,4087,0,0;QS=1,0;MQ0F=0 PL 0,27,204 17 1410 . T <*> 0 . DP=9;I16=1,8,0,0,353,13961,0,0,540,32400,0,0,178,4028,0,0;QS=1,0;MQ0F=0 PL 0,27,218 17 1411 . T <*> 0 . DP=9;I16=1,8,0,0,312,11048,0,0,540,32400,0,0,175,3975,0,0;QS=1,0;MQ0F=0 PL 0,27,194 17 1412 . A <*> 0 . DP=9;I16=1,8,0,0,305,10647,0,0,540,32400,0,0,171,3879,0,0;QS=1,0;MQ0F=0 PL 0,27,192 17 1413 . C <*> 0 . DP=9;I16=1,8,0,0,338,12864,0,0,540,32400,0,0,167,3791,0,0;QS=1,0;MQ0F=0 PL 0,27,209 17 1414 . T <*> 0 . DP=9;I16=1,8,0,0,354,14134,0,0,540,32400,0,0,163,3711,0,0;QS=1,0;MQ0F=0 PL 0,27,221 17 1415 . T <*> 0 . DP=9;I16=1,8,0,0,339,12861,0,0,540,32400,0,0,158,3590,0,0;QS=1,0;MQ0F=0 PL 0,27,208 17 1416 . A <*> 0 . DP=9;I16=1,8,0,0,321,11655,0,0,540,32400,0,0,153,3479,0,0;QS=1,0;MQ0F=0 PL 0,27,199 17 1417 . C <*> 0 . DP=8;I16=1,7,0,0,322,13014,0,0,480,28800,0,0,149,3377,0,0;QS=1,0;MQ0F=0 PL 0,24,211 17 1418 . T <*> 0 . DP=8;I16=1,7,0,0,315,12475,0,0,480,28800,0,0,145,3283,0,0;QS=1,0;MQ0F=0 PL 0,24,207 17 1419 . A <*> 0 . DP=8;I16=1,7,0,0,298,11188,0,0,480,28800,0,0,141,3197,0,0;QS=1,0;MQ0F=0 PL 0,24,199 17 1420 . T <*> 0 . DP=8;I16=1,7,0,0,278,9894,0,0,480,28800,0,0,137,3119,0,0;QS=1,0;MQ0F=0 PL 0,24,185 17 1421 . G <*> 0 . DP=8;I16=1,7,0,0,289,10571,0,0,480,28800,0,0,133,3049,0,0;QS=1,0;MQ0F=0 PL 0,24,191 17 1422 . C <*> 0 . DP=6;I16=1,5,0,0,238,9522,0,0,360,21600,0,0,131,2985,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 1423 . T <*> 0 . DP=6;I16=1,5,0,0,242,9796,0,0,360,21600,0,0,129,2925,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 1424 . C <*> 0 . DP=6;I16=1,5,0,0,224,8628,0,0,360,21600,0,0,127,2869,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 1425 . C <*> 0 . DP=6;I16=1,5,0,0,235,9297,0,0,360,21600,0,0,125,2817,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 1426 . T <*> 0 . DP=6;I16=1,5,0,0,248,10316,0,0,360,21600,0,0,123,2769,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 1427 . T <*> 0 . DP=6;I16=1,5,0,0,231,8983,0,0,360,21600,0,0,121,2725,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 1428 . G <*> 0 . DP=6;I16=1,5,0,0,215,8003,0,0,360,21600,0,0,119,2685,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 1429 . G <*> 0 . DP=6;I16=1,5,0,0,193,6817,0,0,360,21600,0,0,117,2649,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 1430 . C <*> 0 . DP=6;I16=1,5,0,0,203,7173,0,0,360,21600,0,0,115,2617,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 1431 . C <*> 0 . DP=6;I16=1,5,0,0,218,8024,0,0,360,21600,0,0,113,2589,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 1432 . A <*> 0 . DP=6;I16=1,5,0,0,221,8225,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 1433 . T <*> 0 . DP=6;I16=1,5,0,0,230,8890,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 1434 . T <*> 0 . DP=6;I16=1,5,0,0,236,9342,0,0,360,21600,0,0,107,2529,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 1435 . T <*> 0 . DP=6;I16=1,5,0,0,235,9247,0,0,360,21600,0,0,105,2517,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 1436 . C <*> 0 . DP=6;I16=1,5,0,0,215,7865,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 1437 . T <*> 0 . DP=5;I16=1,4,0,0,197,7827,0,0,300,18000,0,0,101,2455,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 1438 . C <*> 0 . DP=5;I16=1,4,0,0,193,7559,0,0,300,18000,0,0,99,2405,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 1439 . T <*> 0 . DP=5;I16=1,4,0,0,190,7308,0,0,300,18000,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 1440 . A <*> 0 . DP=4;I16=1,3,0,0,164,6732,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 1441 . G <*> 0 . DP=4;I16=1,3,0,0,155,6061,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 1442 . G <*> 0 . DP=4;I16=1,3,0,0,145,5303,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 1443 . T <*> 0 . DP=4;I16=1,3,0,0,151,5715,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 1444 . A <*> 0 . DP=4;I16=1,3,0,0,150,5630,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 1445 . T <*> 0 . DP=5;I16=2,3,0,0,194,7650,0,0,300,18000,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 1446 . T <*> 0 . DP=5;I16=2,3,0,0,190,7276,0,0,300,18000,0,0,90,2052,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1447 . G <*> 0 . DP=5;I16=2,3,0,0,179,6671,0,0,300,18000,0,0,89,1979,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 1448 . G <*> 0 . DP=5;I16=2,3,0,0,171,6007,0,0,300,18000,0,0,88,1912,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 1449 . T <*> 0 . DP=5;I16=2,3,0,0,174,6280,0,0,300,18000,0,0,87,1851,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 1450 . A <*> 0 . DP=5;I16=2,3,0,0,190,7256,0,0,300,18000,0,0,86,1796,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1451 . T <*> 0 . DP=5;I16=2,3,0,0,181,6669,0,0,300,18000,0,0,85,1747,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1452 . A <*> 0 . DP=5;I16=2,3,0,0,168,5912,0,0,300,18000,0,0,84,1704,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 1453 . T <*> 0 . DP=5;I16=2,3,0,0,189,7229,0,0,300,18000,0,0,83,1667,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1454 . T <*> 0 . DP=5;I16=2,3,0,0,191,7335,0,0,300,18000,0,0,82,1636,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 1455 . G <*> 0 . DP=5;I16=2,3,0,0,168,5932,0,0,300,18000,0,0,81,1611,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 1456 . T <*> 0 . DP=5;I16=2,3,0,0,197,7771,0,0,300,18000,0,0,80,1592,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 1457 . G <*> 0 . DP=5;I16=2,3,0,0,189,7193,0,0,300,18000,0,0,77,1481,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 1458 . T <*> 0 . DP=5;I16=2,3,0,0,190,7292,0,0,300,18000,0,0,74,1380,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1459 . C A,<*> 0 . DP=5;I16=2,2,0,1,164,6734,24,576,240,14400,60,3600,69,1285,2,4;QS=0.87234,0.12766,0;SGB=-0.379885;RPBZ=1.41421;MQBZ=0;MQSBZ=0;BQBZ=-1.41421;SCBZ=-0.5;MQ0F=0 PL 9,0,135,21,138,152 17 1460 . T <*> 0 . DP=5;I16=2,3,0,0,195,7679,0,0,300,18000,0,0,68,1208,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 1461 . G <*> 0 . DP=5;I16=2,3,0,0,173,6171,0,0,300,18000,0,0,65,1137,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 1462 . C G,<*> 0 . DP=4;I16=1,2,1,0,119,4745,5,25,180,10800,60,3600,46,786,17,289;QS=0.959677,0.0403226,0;SGB=-0.379885;RPBZ=-1.34164;MQBZ=0;MQSBZ=0;BQBZ=-1.34164;SCBZ=-0.57735;MQ0F=0 PL 0,5,106,9,109,107 17 1463 . T <*> 0 . DP=4;I16=2,2,0,0,151,5805,0,0,240,14400,0,0,61,1021,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 1464 . G <*> 0 . DP=5;I16=2,3,0,0,165,5535,0,0,300,18000,0,0,59,975,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 1465 . T <*> 0 . DP=5;I16=2,3,0,0,191,7315,0,0,300,18000,0,0,58,938,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 1466 . G <*> 0 . DP=5;I16=2,3,0,0,187,7027,0,0,300,18000,0,0,57,911,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 1467 . A <*> 0 . DP=5;I16=2,3,0,0,177,6425,0,0,300,18000,0,0,56,894,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 1468 . A <*> 0 . DP=5;I16=2,3,0,0,181,6661,0,0,300,18000,0,0,55,887,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1469 . C <*> 0 . DP=5;I16=2,3,0,0,184,6832,0,0,300,18000,0,0,54,890,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 1470 . T <*> 0 . DP=5;I16=2,3,0,0,190,7290,0,0,300,18000,0,0,53,903,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 1471 . G <*> 0 . DP=4;I16=2,2,0,0,139,4921,0,0,240,14400,0,0,52,874,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 1472 . T <*> 0 . DP=4;I16=2,2,0,0,146,5482,0,0,240,14400,0,0,51,851,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 1473 . C <*> 0 . DP=4;I16=2,2,0,0,153,5877,0,0,240,14400,0,0,50,834,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 1474 . C <*> 0 . DP=4;I16=2,2,0,0,154,5950,0,0,240,14400,0,0,49,823,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 1475 . T <*> 0 . DP=4;I16=2,2,0,0,170,7234,0,0,240,14400,0,0,48,818,0,0;QS=1,0;MQ0F=0 PL 0,12,155 17 1476 . T <*> 0 . DP=4;I16=2,2,0,0,153,5877,0,0,240,14400,0,0,47,819,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 1477 . G <*> 0 . DP=4;I16=2,2,0,0,147,5453,0,0,240,14400,0,0,46,826,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 1478 . G <*> 0 . DP=4;I16=2,2,0,0,118,4498,0,0,240,14400,0,0,45,839,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 1479 . C <*> 0 . DP=3;I16=1,2,0,0,112,4230,0,0,180,10800,0,0,42,854,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1480 . C <*> 0 . DP=3;I16=1,2,0,0,109,4045,0,0,180,10800,0,0,42,882,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 1481 . T <*> 0 . DP=3;I16=1,2,0,0,111,4133,0,0,180,10800,0,0,42,914,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 1482 . G <*> 0 . DP=2;I16=1,1,0,0,75,2825,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 1483 . T <*> 0 . DP=3;I16=1,2,0,0,105,3827,0,0,180,10800,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1484 . T <*> 0 . DP=3;I16=1,2,0,0,111,4229,0,0,180,10800,0,0,46,1026,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1485 . T <*> 0 . DP=3;I16=1,2,0,0,98,3340,0,0,180,10800,0,0,48,1070,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 1486 . G <*> 0 . DP=3;I16=1,2,0,0,115,4411,0,0,180,10800,0,0,50,1118,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1487 . G <*> 0 . DP=3;I16=1,2,0,0,103,3537,0,0,180,10800,0,0,52,1170,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 1488 . T <*> 0 . DP=3;I16=1,2,0,0,108,3914,0,0,180,10800,0,0,54,1226,0,0;QS=1,0;MQ0F=0 PL 0,9,102 17 1489 . G <*> 0 . DP=3;I16=1,2,0,0,99,3293,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 1490 . A <*> 0 . DP=3;I16=1,2,0,0,97,3541,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 1491 . C <*> 0 . DP=3;I16=1,2,0,0,82,2558,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,79 17 1492 . G <*> 0 . DP=3;I16=1,2,0,0,106,3764,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1493 . G <*> 0 . DP=3;I16=1,2,0,0,113,4273,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1494 . G <*> 0 . DP=3;I16=1,2,0,0,113,4317,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1495 . T <*> 0 . DP=3;I16=1,2,0,0,111,4149,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 1496 . G <*> 0 . DP=3;I16=1,2,0,0,114,4356,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1497 . A <*> 0 . DP=3;I16=1,2,0,0,120,4814,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1498 . G <*> 0 . DP=3;I16=1,2,0,0,119,4729,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1499 . G <*> 0 . DP=3;I16=1,2,0,0,114,4358,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1500 . A <*> 0 . DP=3;I16=1,2,0,0,122,4982,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1501 . G <*> 0 . DP=3;I16=1,2,0,0,106,3806,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1502 . C <*> 0 . DP=3;I16=1,2,0,0,111,4149,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 1503 . A <*> 0 . DP=3;I16=1,2,0,0,115,4469,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1504 . G <*> 0 . DP=3;I16=1,2,0,0,118,4654,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 1505 . G <*> 0 . DP=3;I16=1,2,0,0,121,4901,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1506 . G <*> 0 . DP=3;I16=1,2,0,0,118,4692,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1507 . A <*> 0 . DP=3;I16=1,2,0,0,121,4885,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1508 . C <*> 0 . DP=3;I16=1,2,0,0,118,4642,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1509 . A <*> 0 . DP=3;I16=1,2,0,0,129,5553,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,122 17 1510 . G <*> 0 . DP=3;I16=1,2,0,0,118,4658,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 1511 . A <*> 0 . DP=3;I16=1,2,0,0,116,4552,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1512 . A <*> 0 . DP=3;I16=1,2,0,0,115,4569,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1513 . G <*> 0 . DP=3;I16=1,2,0,0,114,4370,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1514 . G <*> 0 . DP=3;I16=1,2,0,0,115,4427,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1515 . G <*> 0 . DP=3;I16=1,2,0,0,107,3837,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 1516 . T <*> 0 . DP=3;I16=1,2,0,0,112,4182,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1517 . C <*> 0 . DP=3;I16=1,2,0,0,102,3542,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 1518 . C <*> 0 . DP=3;I16=1,2,0,0,101,3515,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 1519 . T <*> 0 . DP=3;I16=1,2,0,0,117,4601,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1520 . G <*> 0 . DP=3;I16=1,2,0,0,110,4058,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 1521 . C <*> 0 . DP=3;I16=1,2,0,0,93,3051,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 1522 . G <*> 0 . DP=3;I16=1,2,0,0,96,3122,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 1523 . T <*> 0 . DP=3;I16=1,2,0,0,114,4346,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1524 . G <*> 0 . DP=3;I16=1,2,0,0,109,4035,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 1525 . C <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1526 . C <*> 0 . DP=3;I16=1,2,0,0,112,4226,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1527 . C <*> 0 . DP=3;I16=1,2,0,0,119,4721,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1528 . T <*> 0 . DP=3;I16=1,2,0,0,120,4818,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 1529 . G <*> 0 . DP=3;I16=1,2,0,0,111,4121,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 1530 . C <*> 0 . DP=3;I16=1,2,0,0,112,4182,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1531 . C <*> 0 . DP=3;I16=1,2,0,0,111,4145,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 1532 . T <*> 0 . DP=3;I16=1,2,0,0,127,5379,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,120 17 1533 . T <*> 0 . DP=3;I16=1,2,0,0,113,4325,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1534 . C <*> 0 . DP=3;I16=1,2,0,0,115,4437,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1535 . A <*> 0 . DP=3;I16=1,2,0,0,104,3750,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 1536 . C <*> 0 . DP=3;I16=1,2,0,0,116,4488,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1537 . A <*> 0 . DP=3;I16=1,2,0,0,122,4966,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1538 . A <*> 0 . DP=3;I16=1,2,0,0,119,4753,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1539 . G <*> 0 . DP=3;I16=1,2,0,0,124,5134,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 1540 . C <*> 0 . DP=3;I16=1,2,0,0,108,3920,0,0,180,10800,0,0,54,1226,0,0;QS=1,0;MQ0F=0 PL 0,9,102 17 1541 . C <*> 0 . DP=3;I16=1,2,0,0,114,4374,0,0,180,10800,0,0,52,1170,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1542 . C <*> 0 . DP=4;I16=2,2,0,0,148,5532,0,0,240,14400,0,0,50,1118,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 1543 . C <*> 0 . DP=4;I16=2,2,0,0,154,5970,0,0,240,14400,0,0,49,1071,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 1544 . T <*> 0 . DP=4;I16=2,2,0,0,162,6562,0,0,240,14400,0,0,48,1030,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 1545 . G <*> 0 . DP=4;I16=2,2,0,0,142,5116,0,0,240,14400,0,0,47,995,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 1546 . G <*> 0 . DP=3;I16=1,2,0,0,117,4601,0,0,180,10800,0,0,47,965,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1547 . A <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,47,939,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1548 . A <*> 0 . DP=3;I16=1,2,0,0,122,4994,0,0,180,10800,0,0,47,917,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1549 . G <*> 0 . DP=3;I16=1,2,0,0,121,4897,0,0,180,10800,0,0,47,899,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 1550 . G <*> 0 . DP=3;I16=1,2,0,0,116,4506,0,0,180,10800,0,0,47,885,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1551 . A <*> 0 . DP=3;I16=1,2,0,0,114,4356,0,0,180,10800,0,0,47,875,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1552 . A <*> 0 . DP=3;I16=1,2,0,0,117,4577,0,0,180,10800,0,0,47,869,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1553 . A <*> 0 . DP=3;I16=1,2,0,0,122,4970,0,0,180,10800,0,0,47,867,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1554 . G <*> 0 . DP=3;I16=1,2,0,0,107,3841,0,0,180,10800,0,0,47,869,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 1555 . T <*> 0 . DP=3;I16=1,2,0,0,114,4374,0,0,180,10800,0,0,47,875,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1556 . T <*> 0 . DP=3;I16=1,2,0,0,116,4486,0,0,180,10800,0,0,47,885,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1557 . G <*> 0 . DP=3;I16=1,2,0,0,107,3821,0,0,180,10800,0,0,47,899,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 1558 . T <*> 0 . DP=3;I16=1,2,0,0,118,4646,0,0,180,10800,0,0,47,917,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1559 . T <*> 0 . DP=3;I16=1,2,0,0,109,4043,0,0,180,10800,0,0,46,890,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 1560 . T <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,45,869,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 1561 . T <*> 0 . DP=3;I16=1,2,0,0,113,4257,0,0,180,10800,0,0,44,854,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1562 . G <*> 0 . DP=3;I16=1,2,0,0,115,4421,0,0,180,10800,0,0,43,845,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1563 . G <*> 0 . DP=3;I16=1,2,0,0,117,4577,0,0,180,10800,0,0,42,842,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 1564 . G <*> 0 . DP=3;I16=1,2,0,0,101,3421,0,0,180,10800,0,0,41,845,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 1565 . A <*> 0 . DP=2;I16=1,1,0,0,71,2533,0,0,120,7200,0,0,41,853,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1566 . T <*> 0 . DP=2;I16=1,1,0,0,78,3042,0,0,120,7200,0,0,41,865,0,0;QS=1,0;MQ0F=0 PL 0,6,78 17 1567 . C <*> 0 . DP=2;I16=1,1,0,0,72,2610,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 1568 . T <*> 0 . DP=2;I16=1,1,0,0,74,2756,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 1569 . C <*> 0 . DP=2;I16=1,1,0,0,76,2890,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,76 17 1570 . T <*> 0 . DP=2;I16=1,1,0,0,71,2545,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1571 . G <*> 0 . DP=2;I16=1,1,0,0,70,2450,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 1572 . C <*> 0 . DP=2;I16=1,1,0,0,70,2522,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 1573 . A <*> 0 . DP=2;I16=1,1,0,0,50,1700,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQ0F=0 PL 0,6,50 17 1574 . C <*> 0 . DP=2;I16=1,1,0,0,40,1448,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQ0F=0 PL 0,6,41 17 1575 . C <*> 0 . DP=2;I16=1,1,0,0,71,2545,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1576 . C <*> 0 . DP=2;I16=1,1,0,0,78,3050,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQ0F=0 PL 0,6,78 17 1577 . T <*> 0 . DP=2;I16=1,1,0,0,77,2989,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQ0F=0 PL 0,6,77 17 1578 . C <*> 0 . DP=2;I16=1,1,0,0,77,2977,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQ0F=0 PL 0,6,77 17 1579 . A <*> 0 . DP=2;I16=1,1,0,0,80,3200,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 1580 . G <*> 0 . DP=2;I16=1,1,0,0,77,2977,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQ0F=0 PL 0,6,77 17 1581 . C <*> 0 . DP=2;I16=1,1,0,0,71,2581,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1582 . C <*> 0 . DP=2;I16=1,1,0,0,75,2853,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 1583 . T <*> 0 . DP=2;I16=1,1,0,0,74,2810,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 1584 . G <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 1585 . G <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 17 1586 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1587 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 17 1588 . A <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 1589 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1590 . C <*> 0 . DP=2;I16=1,1,0,0,71,2525,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1591 . T <*> 0 . DP=2;I16=1,1,0,0,73,2705,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1592 . T <*> 0 . DP=2;I16=1,1,0,0,62,1972,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQ0F=0 PL 0,6,62 17 1593 . G <*> 0 . DP=2;I16=1,1,0,0,60,2042,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 1594 . T <*> 0 . DP=2;I16=1,1,0,0,80,3200,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 1595 . G <*> 0 . DP=2;I16=1,1,0,0,69,2421,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 1596 . C <*> 0 . DP=2;I16=1,1,0,0,74,2756,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 1597 . C <*> 0 . DP=2;I16=1,1,0,0,73,2749,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1598 . C <*> 0 . DP=2;I16=1,1,0,0,68,2512,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 1599 . A <*> 0 . DP=2;I16=1,1,0,0,76,2890,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQ0F=0 PL 0,6,76 17 1600 . T <*> 0 . DP=2;I16=1,1,0,0,79,3125,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQ0F=0 PL 0,6,79 17 1601 . C <*> 0 . DP=2;I16=1,1,0,0,78,3092,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,78 17 1602 . T <*> 0 . DP=2;I16=1,1,0,0,85,3617,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,85 17 1603 . G <*> 0 . DP=2;I16=1,1,0,0,75,2817,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 1604 . G <*> 0 . DP=2;I16=1,1,0,0,66,2178,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 1605 . T <*> 0 . DP=2;I16=1,1,0,0,61,1901,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 1606 . G <*> 0 . DP=2;I16=1,1,0,0,56,1570,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 1607 . A <*> 0 . DP=2;I16=1,1,0,0,55,1825,0,0,120,7200,0,0,42,914,0,0;QS=1,0;MQ0F=0 PL 0,6,55 17 1608 . C <*> 0 . DP=2;I16=1,1,0,0,62,2050,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,62 17 1609 . C <*> 0 . DP=2;I16=1,1,0,0,71,2561,0,0,120,7200,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1610 . C <*> 0 . DP=2;I16=1,1,0,0,57,1889,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,57 17 1611 . C <*> 0 . DP=2;I16=1,1,0,0,67,2329,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 1612 . T <*> 0 . DP=2;I16=1,1,0,0,83,3457,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,83 17 1613 . C <*> 0 . DP=2;I16=1,1,0,0,63,2129,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 1614 . A <*> 0 . DP=2;I16=1,1,0,0,69,2465,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 1615 . C <*> 0 . DP=2;I16=1,1,0,0,51,1445,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,51 17 1616 . T C,<*> 0 . DP=2;I16=1,0,0,1,42,1764,1,1,60,3600,60,3600,25,625,25,625;QS=0.913043,0.0869565,0;SGB=-0.379885;RPBZ=-1;MQBZ=0;MQSBZ=0;BQBZ=-1;SCBZ=0;MQ0F=0 PL 0,1,37,3,40,39 17 1617 . C <*> 0 . DP=2;I16=1,1,0,0,53,1885,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,53 17 1618 . A <*> 0 . DP=2;I16=1,1,0,0,81,3281,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,81 17 1619 . G <*> 0 . DP=2;I16=1,1,0,0,67,2269,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 1620 . C <*> 0 . DP=2;I16=1,1,0,0,56,1906,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 1621 . C <*> 0 . DP=2;I16=1,1,0,0,56,1810,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 1622 . A <*> 0 . DP=2;I16=1,1,0,0,52,1640,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,52 17 1623 . C <*> 0 . DP=2;I16=1,1,0,0,41,1385,0,0,120,7200,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,6,40 17 1624 . C <*> 0 . DP=2;I16=1,1,0,0,48,1602,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,48 17 1625 . A <*> 0 . DP=2;I16=1,1,0,0,80,3202,0,0,120,7200,0,0,42,914,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 1626 . G <*> 0 . DP=2;I16=1,1,0,0,63,2009,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 1627 . A <*> 0 . DP=2;I16=1,1,0,0,72,2610,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 1628 . C <*> 0 . DP=2;I16=1,1,0,0,57,1805,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,57 17 1629 . T <*> 0 . DP=2;I16=1,1,0,0,79,3161,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,79 17 1630 . T <*> 0 . DP=2;I16=1,1,0,0,73,2665,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1631 . C <*> 0 . DP=2;I16=1,1,0,0,61,2041,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 1632 . C <*> 0 . DP=2;I16=1,1,0,0,61,2041,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 1633 . A <*> 0 . DP=2;I16=1,1,0,0,73,2705,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1634 . C <*> 0 . DP=2;I16=1,1,0,0,59,1885,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQ0F=0 PL 0,6,59 17 1635 . G <*> 0 . DP=2;I16=1,1,0,0,59,1741,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQ0F=0 PL 0,6,59 17 1636 . A <*> 0 . DP=2;I16=1,1,0,0,66,2306,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 1637 . C <*> 0 . DP=2;I16=1,1,0,0,60,1898,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 1638 . A <*> 0 . DP=2;I16=1,1,0,0,78,3042,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQ0F=0 PL 0,6,78 17 1639 . G <*> 0 . DP=2;I16=1,1,0,0,68,2314,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 1640 . G <*> 0 . DP=2;I16=1,1,0,0,51,1481,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQ0F=0 PL 0,6,51 17 1641 . C <*> 0 . DP=3;I16=1,2,0,0,67,2129,0,0,180,10800,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,66 17 1642 . T <*> 0 . DP=3;I16=1,2,0,0,105,3689,0,0,180,10800,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 1643 . C <*> 0 . DP=2;I16=0,2,0,0,61,1873,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 1644 . C <*> 0 . DP=2;I16=0,2,0,0,59,1745,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,54 17 1645 . A <*> 0 . DP=2;I16=0,2,0,0,53,1417,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,49 17 1646 . G <*> 0 . DP=2;I16=0,2,0,0,53,1409,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,48 17 1647 . C <*> 0 . DP=2;I16=0,2,0,0,39,761,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,35 17 1648 . C <*> 0 . DP=2;I16=0,2,0,0,48,1184,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,44 17 1649 . T <*> 0 . DP=2;I16=0,2,0,0,61,1901,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 1650 . C <*> 0 . DP=2;I16=0,2,0,0,24,290,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,22 17 1651 . G <*> 0 . DP=3;I16=1,2,0,0,92,2840,0,0,149,8041,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,86 17 1652 . G <*> 0 . DP=3;I16=1,2,0,0,64,1806,0,0,149,8041,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,57 17 1653 . C <*> 0 . DP=3;I16=1,2,0,0,94,3110,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,81 17 1654 . A <*> 0 . DP=3;I16=1,2,0,0,91,2933,0,0,149,8041,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 1655 . C <*> 0 . DP=3;I16=1,2,0,0,88,2942,0,0,149,8041,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,79 17 1656 . C <*> 0 . DP=3;I16=1,2,0,0,93,2969,0,0,149,8041,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 1657 . T <*> 0 . DP=3;I16=1,2,0,0,104,3770,0,0,149,8041,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,85 17 1658 . T <*> 0 . DP=3;I16=1,2,0,0,97,3205,0,0,149,8041,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 1659 . C <*> 0 . DP=4;I16=1,3,0,0,94,2998,0,0,209,11641,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,80 17 1660 . A <*> 0 . DP=4;I16=1,3,0,0,149,5595,0,0,209,11641,0,0,84,1956,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 1661 . G <*> 0 . DP=4;I16=1,3,0,0,118,3508,0,0,209,11641,0,0,85,1975,0,0;QS=1,0;MQ0F=0 PL 0,12,98 17 1662 . C <*> 0 . DP=4;I16=1,3,0,0,123,3901,0,0,209,11641,0,0,86,1996,0,0;QS=1,0;MQ0F=0 PL 0,12,100 17 1663 . C <*> 0 . DP=4;I16=1,3,0,0,124,3894,0,0,209,11641,0,0,87,2019,0,0;QS=1,0;MQ0F=0 PL 0,12,101 17 1664 . A <*> 0 . DP=4;I16=1,3,0,0,130,4468,0,0,209,11641,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,12,109 17 1665 . T C,<*> 0 . DP=4;I16=0,2,1,1,68,2330,58,1924,120,7200,89,4441,50,1250,39,821;QS=0.591304,0.408696,0;VDB=0.1;SGB=-0.453602;RPBZ=-1.54919;MQBZ=-1;MQSBZ=1.73205;BQBZ=0;SCBZ=0.408248;MQ0F=0 PL 35,0,51,41,57,90 17 1666 . G <*> 0 . DP=4;I16=1,3,0,0,129,4165,0,0,209,11641,0,0,88,2002,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 1667 . G <*> 0 . DP=4;I16=1,3,0,0,144,5304,0,0,209,11641,0,0,87,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 1668 . A <*> 0 . DP=4;I16=1,3,0,0,153,5865,0,0,209,11641,0,0,86,1882,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 1669 . C <*> 0 . DP=4;I16=1,3,0,0,140,4974,0,0,209,11641,0,0,85,1831,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 1670 . A <*> 0 . DP=4;I16=1,3,0,0,158,6270,0,0,209,11641,0,0,84,1786,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 1671 . G <*> 0 . DP=4;I16=1,3,0,0,133,4551,0,0,209,11641,0,0,83,1747,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 1672 . T <*> 0 . DP=4;I16=1,3,0,0,134,4662,0,0,209,11641,0,0,82,1714,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 1673 . T <*> 0 . DP=4;I16=1,3,0,0,138,4884,0,0,209,11641,0,0,81,1687,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 1674 . C <*> 0 . DP=4;I16=1,3,0,0,115,3581,0,0,209,11641,0,0,80,1666,0,0;QS=1,0;MQ0F=0 PL 0,12,96 17 1675 . C <*> 0 . DP=4;I16=1,3,0,0,80,2324,0,0,209,11641,0,0,79,1651,0,0;QS=1,0;MQ0F=0 PL 0,12,65 17 1676 . G <*> 0 . DP=4;I16=1,3,0,0,107,3465,0,0,209,11641,0,0,78,1642,0,0;QS=1,0;MQ0F=0 PL 0,12,95 17 1677 . C <*> 0 . DP=4;I16=1,3,0,0,93,3133,0,0,209,11641,0,0,76,1588,0,0;QS=1,0;MQ0F=0 PL 0,12,74 17 1678 . C <*> 0 . DP=4;I16=1,3,0,0,110,3654,0,0,209,11641,0,0,74,1538,0,0;QS=1,0;MQ0F=0 PL 0,12,87 17 1679 . A G,<*> 0 . DP=4;I16=1,2,0,1,125,5211,6,36,149,8041,60,3600,47,867,25,625;QS=0.94958,0.0504202,0;SGB=-0.379885;RPBZ=-0.447214;MQBZ=0.57735;MQSBZ=1.73205;BQBZ=-1.41421;SCBZ=1.41421;MQ0F=0 PL 0,4,99,9,102,101 17 1680 . G <*> 0 . DP=4;I16=1,3,0,0,130,4382,0,0,209,11641,0,0,70,1450,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 1681 . C <*> 0 . DP=4;I16=1,3,0,0,95,2849,0,0,209,11641,0,0,68,1412,0,0;QS=1,0;MQ0F=0 PL 0,12,74 17 1682 . G <*> 0 . DP=4;I16=1,3,0,0,111,3081,0,0,209,11641,0,0,66,1378,0,0;QS=1,0;MQ0F=0 PL 0,12,98 17 1683 . T <*> 0 . DP=4;I16=1,3,0,0,111,3617,0,0,209,11641,0,0,64,1348,0,0;QS=1,0;MQ0F=0 PL 0,12,95 17 1684 . T <*> 0 . DP=4;I16=1,3,0,0,133,4611,0,0,209,11641,0,0,62,1322,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 1685 . G <*> 0 . DP=4;I16=1,3,0,0,128,4242,0,0,209,11641,0,0,60,1300,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 1686 . C <*> 0 . DP=4;I16=1,3,0,0,127,4127,0,0,209,11641,0,0,58,1282,0,0;QS=1,0;MQ0F=0 PL 0,12,103 17 1687 . C <*> 0 . DP=4;I16=1,3,0,0,129,4325,0,0,209,11641,0,0,56,1268,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 1688 . C <*> 0 . DP=4;I16=1,3,0,0,147,5445,0,0,209,11641,0,0,54,1258,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 1689 . T A,<*> 0 . DP=4;I16=1,2,0,1,111,4185,33,1089,149,8041,60,3600,27,627,25,625;QS=0.744186,0.255814,0;SGB=-0.379885;RPBZ=-0.447214;MQBZ=0.57735;MQSBZ=1.73205;BQBZ=-0.447214;SCBZ=1;MQ0F=0 PL 21,0,79,30,82,106 17 1690 . C <*> 0 . DP=4;I16=1,3,0,0,120,3996,0,0,209,11641,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,12,95 17 1691 . T <*> 0 . DP=2;I16=1,1,0,0,71,2633,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,57 17 1692 . G <*> 0 . DP=2;I16=1,1,0,0,73,2705,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 1693 . T <*> 0 . DP=4;I16=3,1,0,0,130,4356,0,0,209,11641,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 1694 . T <*> 0 . DP=4;I16=3,1,0,0,133,4437,0,0,209,11641,0,0,52,1252,0,0;QS=1,0;MQ0F=0 PL 0,12,114 17 1695 . C <*> 0 . DP=4;I16=3,1,0,0,143,5117,0,0,209,11641,0,0,54,1258,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 1696 . T <*> 0 . DP=4;I16=3,1,0,0,138,5226,0,0,209,11641,0,0,56,1268,0,0;QS=1,0;MQ0F=0 PL 0,12,108 17 1697 . G <*> 0 . DP=4;I16=3,1,0,0,132,4424,0,0,209,11641,0,0,58,1282,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 1698 . C <*> 0 . DP=4;I16=3,1,0,0,135,4661,0,0,209,11641,0,0,60,1300,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 1699 . T <*> 0 . DP=4;I16=3,1,0,0,144,5250,0,0,209,11641,0,0,62,1322,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 1700 . G <*> 0 . DP=4;I16=3,1,0,0,133,4485,0,0,209,11641,0,0,64,1348,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 1701 . T <*> 0 . DP=4;I16=3,1,0,0,152,5794,0,0,209,11641,0,0,66,1378,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 1702 . T <*> 0 . DP=4;I16=3,1,0,0,141,5099,0,0,209,11641,0,0,67,1363,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 1703 . T <*> 0 . DP=4;I16=3,1,0,0,141,5087,0,0,209,11641,0,0,68,1354,0,0;QS=1,0;MQ0F=0 PL 0,12,114 17 1704 . T <*> 0 . DP=5;I16=4,1,0,0,163,5477,0,0,269,15241,0,0,69,1351,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 1705 . C <*> 0 . DP=5;I16=4,1,0,0,156,5206,0,0,269,15241,0,0,71,1355,0,0;QS=1,0;MQ0F=0 PL 0,15,120 17 1706 . T <*> 0 . DP=5;I16=4,1,0,0,193,7555,0,0,269,15241,0,0,73,1367,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 1707 . C <*> 0 . DP=5;I16=4,1,0,0,173,6169,0,0,269,15241,0,0,75,1387,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 1708 . T <*> 0 . DP=5;I16=4,1,0,0,173,6131,0,0,269,15241,0,0,77,1415,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 1709 . A <*> 0 . DP=5;I16=4,1,0,0,168,5822,0,0,269,15241,0,0,79,1451,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 1710 . C <*> 0 . DP=5;I16=4,1,0,0,158,5102,0,0,269,15241,0,0,81,1495,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 1711 . C <*> 0 . DP=5;I16=4,1,0,0,174,6146,0,0,269,15241,0,0,83,1547,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 1712 . A <*> 0 . DP=5;I16=4,1,0,0,175,6151,0,0,269,15241,0,0,85,1607,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 1713 . G <*> 0 . DP=5;I16=4,1,0,0,145,4763,0,0,269,15241,0,0,87,1675,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 1714 . A <*> 0 . DP=5;I16=4,1,0,0,147,4981,0,0,269,15241,0,0,89,1751,0,0;QS=1,0;MQ0F=0 PL 0,15,111 17 1715 . A <*> 0 . DP=5;I16=4,1,0,0,179,6433,0,0,269,15241,0,0,91,1835,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 1716 . G <*> 0 . DP=5;I16=4,1,0,0,165,5679,0,0,269,15241,0,0,93,1927,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 1717 . T <*> 0 . DP=5;I16=4,1,0,0,156,5082,0,0,269,15241,0,0,95,2027,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 1718 . G <*> 0 . DP=5;I16=4,1,0,0,158,5140,0,0,269,15241,0,0,97,2135,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 1719 . C <*> 0 . DP=5;I16=4,1,0,0,144,4878,0,0,269,15241,0,0,97,2149,0,0;QS=1,0;MQ0F=0 PL 0,15,109 17 1720 . C <*> 0 . DP=5;I16=4,1,0,0,134,4650,0,0,269,15241,0,0,97,2167,0,0;QS=1,0;MQ0F=0 PL 0,15,104 17 1721 . C <*> 0 . DP=5;I16=4,1,0,0,151,5197,0,0,269,15241,0,0,97,2189,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 1722 . T <*> 0 . DP=5;I16=4,1,0,0,164,5866,0,0,269,15241,0,0,97,2215,0,0;QS=1,0;MQ0F=0 PL 0,15,123 17 1723 . T <*> 0 . DP=5;I16=4,1,0,0,166,5622,0,0,269,15241,0,0,97,2245,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 1724 . C <*> 0 . DP=5;I16=4,1,0,0,180,6718,0,0,269,15241,0,0,97,2279,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 1725 . C <*> 0 . DP=5;I16=4,1,0,0,168,5834,0,0,269,15241,0,0,97,2317,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 1726 . C <*> 0 . DP=5;I16=4,1,0,0,158,5268,0,0,269,15241,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 1727 . T <*> 0 . DP=5;I16=4,1,0,0,161,5913,0,0,269,15241,0,0,97,2355,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 1728 . C <*> 0 . DP=5;I16=4,1,0,0,184,6832,0,0,269,15241,0,0,98,2356,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 1729 . C <*> 0 . DP=5;I16=4,1,0,0,162,5960,0,0,269,15241,0,0,99,2363,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 1730 . T <*> 0 . DP=5;I16=4,1,0,0,188,7144,0,0,269,15241,0,0,99,2325,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 1731 . C <*> 0 . DP=5;I16=4,1,0,0,179,6673,0,0,269,15241,0,0,99,2291,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 1732 . A <*> 0 . DP=5;I16=4,1,0,0,186,7018,0,0,269,15241,0,0,99,2261,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 1733 . C <*> 0 . DP=5;I16=4,1,0,0,170,5934,0,0,269,15241,0,0,99,2235,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 1734 . C <*> 0 . DP=5;I16=4,1,0,0,176,6536,0,0,269,15241,0,0,99,2213,0,0;QS=1,0;MQ0F=0 PL 0,15,141 17 1735 . T <*> 0 . DP=5;I16=4,1,0,0,193,7605,0,0,269,15241,0,0,99,2195,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 1736 . G T,<*> 0 . DP=5;I16=3,1,1,0,142,5070,6,36,209,11641,60,3600,74,1556,25,625;QS=0.957143,0.0428571,0;SGB=-0.379885;RPBZ=-0.725476;MQBZ=0.5;MQSBZ=0.5;BQBZ=-1.41421;SCBZ=2;MQ0F=0 PL 0,7,111,12,114,112 17 1737 . A <*> 0 . DP=5;I16=4,1,0,0,168,6138,0,0,269,15241,0,0,99,2171,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 1738 . C <*> 0 . DP=5;I16=4,1,0,0,164,5714,0,0,269,15241,0,0,99,2165,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 1739 . C <*> 0 . DP=5;I16=4,1,0,0,172,6730,0,0,269,15241,0,0,99,2163,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 1740 . A <*> 0 . DP=5;I16=4,1,0,0,179,6691,0,0,269,15241,0,0,99,2165,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 1741 . C <*> 0 . DP=5;I16=4,1,0,0,167,5861,0,0,269,15241,0,0,99,2171,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 1742 . T <*> 0 . DP=5;I16=4,1,0,0,188,7314,0,0,269,15241,0,0,99,2181,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 1743 . C <*> 0 . DP=5;I16=4,1,0,0,176,6240,0,0,269,15241,0,0,99,2195,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 1744 . T <*> 0 . DP=5;I16=4,1,0,0,201,8191,0,0,269,15241,0,0,99,2213,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 1745 . G <*> 0 . DP=5;I16=4,1,0,0,181,6773,0,0,269,15241,0,0,99,2235,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 1746 . G <*> 0 . DP=6;I16=5,1,0,0,208,7470,0,0,329,18841,0,0,99,2261,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 1747 . G <*> 0 . DP=6;I16=5,1,0,0,201,7301,0,0,329,18841,0,0,100,2292,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 1748 . G <*> 0 . DP=6;I16=5,1,0,0,204,7098,0,0,329,18841,0,0,101,2329,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 1749 . A <*> 0 . DP=7;I16=6,1,0,0,250,9100,0,0,389,22441,0,0,102,2372,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 1750 . A <*> 0 . DP=7;I16=6,1,0,0,274,10762,0,0,389,22441,0,0,104,2422,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 1751 . A <*> 0 . DP=7;I16=6,1,0,0,264,10182,0,0,389,22441,0,0,106,2480,0,0;QS=1,0;MQ0F=0 PL 0,21,184 17 1752 . T <*> 0 . DP=6;I16=5,1,0,0,223,8367,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQ0F=0 PL 0,18,170 17 1753 . C <*> 0 . DP=6;I16=5,1,0,0,209,7747,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 1754 . C <*> 0 . DP=6;I16=5,1,0,0,212,7624,0,0,360,21600,0,0,113,2589,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 1755 . C <*> 0 . DP=6;I16=5,1,0,0,212,7854,0,0,360,21600,0,0,115,2617,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 1756 . T <*> 0 . DP=6;I16=5,1,0,0,233,9235,0,0,360,21600,0,0,117,2649,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 1757 . C <*> 0 . DP=6;I16=5,1,0,0,227,8795,0,0,360,21600,0,0,119,2685,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 1758 . A <*> 0 . DP=6;I16=5,1,0,0,232,9074,0,0,360,21600,0,0,121,2725,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 1759 . G <*> 0 . DP=6;I16=5,1,0,0,207,7355,0,0,360,21600,0,0,123,2769,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 1760 . C <*> 0 . DP=6;I16=5,1,0,0,208,7642,0,0,360,21600,0,0,125,2817,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 1761 . A <*> 0 . DP=6;I16=5,1,0,0,205,7409,0,0,360,21600,0,0,127,2869,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 1762 . C <*> 0 . DP=6;I16=5,1,0,0,207,7417,0,0,360,21600,0,0,129,2925,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 1763 . C <*> 0 . DP=6;I16=5,1,0,0,211,7629,0,0,360,21600,0,0,131,2985,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 1764 . C <*> 0 . DP=6;I16=5,1,0,0,218,8026,0,0,360,21600,0,0,133,3049,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 1765 . T <*> 0 . DP=6;I16=5,1,0,0,234,9192,0,0,360,21600,0,0,135,3117,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 1766 . C <*> 0 . DP=6;I16=5,1,0,0,212,7528,0,0,360,21600,0,0,137,3189,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 1767 . C <*> 0 . DP=6;I16=5,1,0,0,215,7771,0,0,360,21600,0,0,139,3265,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 1768 . C <*> 0 . DP=6;I16=5,1,0,0,211,7491,0,0,360,21600,0,0,141,3345,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 1769 . T <*> 0 . DP=6;I16=5,1,0,0,242,9834,0,0,360,21600,0,0,141,3331,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 1770 . G <*> 0 . DP=6;I16=5,1,0,0,203,7151,0,0,360,21600,0,0,141,3325,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 1771 . A <*> 0 . DP=6;I16=5,1,0,0,234,9160,0,0,360,21600,0,0,141,3327,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 1772 . G <*> 0 . DP=6;I16=5,1,0,0,203,7277,0,0,360,21600,0,0,140,3286,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 1773 . C <*> 0 . DP=6;I16=5,1,0,0,227,8625,0,0,360,21600,0,0,139,3251,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 1774 . A <*> 0 . DP=6;I16=5,1,0,0,228,8700,0,0,360,21600,0,0,138,3222,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 1775 . T <*> 0 . DP=6;I16=5,1,0,0,199,7101,0,0,360,21600,0,0,136,3148,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 1776 . A <*> 0 . DP=6;I16=5,1,0,0,218,8038,0,0,360,21600,0,0,134,3078,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 1777 . C <*> 0 . DP=6;I16=5,1,0,0,208,7460,0,0,360,21600,0,0,132,3012,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 1778 . C <*> 0 . DP=6;I16=5,1,0,0,224,8452,0,0,360,21600,0,0,130,2950,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 1779 . C <*> 0 . DP=6;I16=5,1,0,0,227,8671,0,0,360,21600,0,0,128,2892,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 1780 . T <*> 0 . DP=6;I16=5,1,0,0,231,9087,0,0,360,21600,0,0,125,2789,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 1781 . A <*> 0 . DP=6;I16=5,1,0,0,205,7719,0,0,360,21600,0,0,122,2692,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 1782 . C <*> 0 . DP=6;I16=5,1,0,0,203,7069,0,0,360,21600,0,0,119,2601,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 1783 . T <*> 0 . DP=6;I16=5,1,0,0,235,9363,0,0,360,21600,0,0,116,2516,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 1784 . C <*> 0 . DP=6;I16=5,1,0,0,187,6971,0,0,360,21600,0,0,113,2437,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 1785 . T <*> 0 . DP=5;I16=4,1,0,0,207,8659,0,0,300,18000,0,0,91,2003,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 1786 . G <*> 0 . DP=5;I16=4,1,0,0,193,7479,0,0,300,18000,0,0,89,1973,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1787 . G <*> 0 . DP=5;I16=4,1,0,0,180,6520,0,0,300,18000,0,0,87,1947,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 1788 . C <*> 0 . DP=5;I16=4,1,0,0,193,7491,0,0,300,18000,0,0,85,1925,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1789 . A <*> 0 . DP=5;I16=4,1,0,0,192,7402,0,0,300,18000,0,0,83,1907,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 1790 . C <*> 0 . DP=5;I16=4,1,0,0,186,6962,0,0,300,18000,0,0,81,1893,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 1791 . A <*> 0 . DP=5;I16=4,1,0,0,190,7288,0,0,300,18000,0,0,79,1883,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 1792 . A <*> 0 . DP=5;I16=4,1,0,0,196,7802,0,0,300,18000,0,0,77,1877,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 1793 . G <*> 0 . DP=5;I16=4,1,0,0,155,4877,0,0,300,18000,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,15,126 17 1794 . C <*> 0 . DP=3;I16=2,1,0,0,102,3566,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 1795 . C <*> 0 . DP=3;I16=2,1,0,0,106,3874,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1796 . C <*> 0 . DP=3;I16=2,1,0,0,108,3992,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,102 17 1797 . A <*> 0 . DP=3;I16=2,1,0,0,98,3494,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,92 17 1798 . C <*> 0 . DP=3;I16=2,1,0,0,105,3789,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 1799 . C <*> 0 . DP=4;I16=2,2,0,0,145,5397,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 1800 . C <*> 0 . DP=4;I16=2,2,0,0,154,5990,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 1801 . T <*> 0 . DP=4;I16=2,2,0,0,164,6762,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 1802 . G <*> 0 . DP=4;I16=2,2,0,0,150,5678,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 1803 . C <*> 0 . DP=4;I16=2,2,0,0,157,6193,0,0,240,14400,0,0,78,1842,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 1804 . A <*> 0 . DP=4;I16=2,2,0,0,158,6252,0,0,240,14400,0,0,78,1804,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 1805 . A <*> 0 . DP=4;I16=2,2,0,0,150,5684,0,0,240,14400,0,0,78,1770,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 1806 . A <*> 0 . DP=4;I16=2,2,0,0,151,5999,0,0,240,14400,0,0,78,1740,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 1807 . G <*> 0 . DP=4;I16=2,2,0,0,155,6057,0,0,240,14400,0,0,78,1714,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 1808 . C <*> 0 . DP=4;I16=2,2,0,0,153,5939,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 1809 . C <*> 0 . DP=4;I16=2,2,0,0,157,6187,0,0,240,14400,0,0,78,1674,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 1810 . C <*> 0 . DP=4;I16=2,2,0,0,159,6353,0,0,240,14400,0,0,78,1660,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 1811 . C <*> 0 . DP=4;I16=2,2,0,0,160,6402,0,0,240,14400,0,0,78,1650,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 1812 . T <*> 0 . DP=4;I16=2,2,0,0,165,6845,0,0,240,14400,0,0,78,1644,0,0;QS=1,0;MQ0F=0 PL 0,12,151 17 1813 . G <*> 0 . DP=4;I16=2,2,0,0,147,5441,0,0,240,14400,0,0,78,1642,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 1814 . A <*> 0 . DP=4;I16=2,2,0,0,162,6566,0,0,240,14400,0,0,78,1644,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 1815 . G <*> 0 . DP=4;I16=2,2,0,0,148,5508,0,0,240,14400,0,0,78,1650,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 1816 . G <*> 0 . DP=4;I16=2,2,0,0,135,4809,0,0,240,14400,0,0,78,1660,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 1817 . C <*> 0 . DP=4;I16=2,2,0,0,146,5370,0,0,240,14400,0,0,78,1674,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 1818 . C <*> 0 . DP=4;I16=2,2,0,0,145,5281,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 1819 . C <*> 0 . DP=4;I16=2,2,0,0,135,4641,0,0,240,14400,0,0,78,1714,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 1820 . G <*> 0 . DP=4;I16=2,2,0,0,128,4142,0,0,240,14400,0,0,78,1740,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 1821 . C <*> 0 . DP=4;I16=2,2,0,0,143,5143,0,0,240,14400,0,0,78,1770,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 1822 . C <*> 0 . DP=4;I16=2,2,0,0,144,5200,0,0,240,14400,0,0,77,1755,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 1823 . C <*> 0 . DP=4;I16=2,2,0,0,151,5705,0,0,240,14400,0,0,76,1746,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 1824 . T <*> 0 . DP=4;I16=2,2,0,0,163,6673,0,0,240,14400,0,0,75,1743,0,0;QS=1,0;MQ0F=0 PL 0,12,149 17 1825 . G <*> 0 . DP=4;I16=2,2,0,0,141,5015,0,0,240,14400,0,0,72,1646,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 1826 . T <*> 0 . DP=4;I16=2,2,0,0,154,5930,0,0,240,14400,0,0,69,1555,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 1827 . G <*> 0 . DP=4;I16=2,2,0,0,150,5654,0,0,240,14400,0,0,66,1470,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 1828 . G <*> 0 . DP=3;I16=2,1,0,0,106,3774,0,0,180,10800,0,0,64,1390,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1829 . C <*> 0 . DP=3;I16=2,1,0,0,109,4021,0,0,180,10800,0,0,62,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 1830 . G <*> 0 . DP=3;I16=2,1,0,0,84,2520,0,0,180,10800,0,0,60,1242,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 1831 . T <*> 0 . DP=3;I16=2,1,0,0,107,3865,0,0,180,10800,0,0,58,1174,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 1832 . C <*> 0 . DP=3;I16=2,1,0,0,111,4125,0,0,180,10800,0,0,56,1110,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 1833 . T <*> 0 . DP=3;I16=2,1,0,0,112,4206,0,0,180,10800,0,0,54,1050,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 1834 . C <*> 0 . DP=3;I16=2,1,0,0,114,4356,0,0,180,10800,0,0,52,994,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1835 . T <*> 0 . DP=3;I16=2,1,0,0,122,5030,0,0,180,10800,0,0,50,942,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 1836 . C <*> 0 . DP=3;I16=2,1,0,0,115,4425,0,0,180,10800,0,0,48,894,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1837 . C <*> 0 . DP=3;I16=2,1,0,0,114,4346,0,0,180,10800,0,0,46,850,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1838 . C <*> 0 . DP=3;I16=2,1,0,0,113,4277,0,0,180,10800,0,0,44,810,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1839 . T <*> 0 . DP=3;I16=2,1,0,0,126,5316,0,0,180,10800,0,0,42,774,0,0;QS=1,0;MQ0F=0 PL 0,9,119 17 1840 . C <*> 0 . DP=3;I16=2,1,0,0,115,4417,0,0,180,10800,0,0,40,742,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 1841 . C <*> 0 . DP=3;I16=2,1,0,0,114,4340,0,0,180,10800,0,0,38,714,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1842 . C <*> 0 . DP=3;I16=2,1,0,0,114,4334,0,0,180,10800,0,0,36,690,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 1843 . T <*> 0 . DP=3;I16=2,1,0,0,114,4356,0,0,180,10800,0,0,34,670,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 1844 . T <*> 0 . DP=3;I16=2,1,0,0,104,3656,0,0,180,10800,0,0,32,654,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 1845 . G <*> 0 . DP=3;I16=2,1,0,0,86,2614,0,0,180,10800,0,0,30,642,0,0;QS=1,0;MQ0F=0 PL 0,9,82 17 1846 . C <*> 0 . DP=3;I16=2,1,0,0,106,3750,0,0,180,10800,0,0,28,634,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1847 . T <*> 0 . DP=2;I16=1,1,0,0,76,2890,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQ0F=0 PL 0,6,76 17 1848 . G <*> 0 . DP=2;I16=1,1,0,0,64,2066,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 1849 . T <*> 0 . DP=2;I16=1,1,0,0,71,2561,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1850 . C <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 1851 . A <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 1852 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 1853 . G <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 1854 . A <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 1855 . C <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 1856 . A <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 1857 . G <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 17 1858 . T <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 1859 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 1860 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 17 1861 . T <*> 0 . DP=1;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 1862 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 17 1863 . C <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 1864 . T <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 1865 . G <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 1866 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 1867 . C <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 1868 . C <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 1869 . A T,<*> 0 . DP=1;I16=0,0,0,1,0,0,42,1764,0,0,60,3600,0,0,25,625;QS=0,1,0;SGB=-0.379885;MQ0F=0 PL 42,3,0,42,3,42 17 1870 . C <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 1871 . C <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 17 1872 . G <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 17 1873 . G <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 17 1874 . G <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 17 1875 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1876 . C <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,41 17 1877 . T <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1878 . C <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 1879 . A <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 1880 . C <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,31 17 1881 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1882 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1883 . A <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,43 17 1884 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1885 . C <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,42 17 1886 . C <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,32 17 1887 . G <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 1888 . C <*> 0 . DP=1;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 1889 . C <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 1890 . C <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,40 17 1891 . T <*> 0 . DP=1;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,39 17 1892 . G <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,37 17 1893 . T <*> 0 . DP=2;I16=1,1,0,0,72,2610,0,0,120,7200,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 1894 . G <*> 0 . DP=2;I16=1,1,0,0,75,2817,0,0,120,7200,0,0,6,26,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 1895 . C <*> 0 . DP=2;I16=1,1,0,0,73,2665,0,0,120,7200,0,0,6,20,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1896 . C <*> 0 . DP=2;I16=1,1,0,0,72,2600,0,0,120,7200,0,0,6,18,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 1897 . G A,<*> 0 . DP=2;I16=1,0,0,1,27,729,37,1369,60,3600,60,3600,4,16,2,4;QS=0.421875,0.578125,0;SGB=-0.379885;RPBZ=1;MQBZ=0;MQSBZ=0;BQBZ=1;SCBZ=0;MQ0F=0 PL 31,0,21,34,24,55 17 1898 . T <*> 0 . DP=3;I16=2,1,0,0,106,3790,0,0,180,10800,0,0,6,26,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 1899 . G <*> 0 . DP=3;I16=2,1,0,0,100,3334,0,0,180,10800,0,0,7,37,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 1900 . T <*> 0 . DP=2;I16=2,0,0,0,76,2890,0,0,120,7200,0,0,9,53,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 1901 . A <*> 0 . DP=2;I16=2,0,0,0,74,2740,0,0,120,7200,0,0,11,73,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 1902 . C <*> 0 . DP=2;I16=2,0,0,0,66,2186,0,0,120,7200,0,0,13,97,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 1903 . C <*> 0 . DP=2;I16=2,0,0,0,69,2393,0,0,120,7200,0,0,15,125,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 1904 . T <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,120,7200,0,0,17,157,0,0;QS=1,0;MQ0F=0 PL 0,6,77 17 1905 . C <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,19,193,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 1906 . T <*> 0 . DP=2;I16=2,0,0,0,82,3364,0,0,120,7200,0,0,21,233,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 1907 . G <*> 0 . DP=2;I16=2,0,0,0,75,2813,0,0,120,7200,0,0,23,277,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 1908 . A <*> 0 . DP=2;I16=2,0,0,0,73,2669,0,0,120,7200,0,0,25,325,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 1909 . G <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,27,377,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1910 . C <*> 0 . DP=2;I16=2,0,0,0,78,3044,0,0,120,7200,0,0,29,433,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1911 . C <*> 0 . DP=2;I16=2,0,0,0,78,3044,0,0,120,7200,0,0,31,493,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 1912 . C <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,33,557,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1913 . T <*> 0 . DP=2;I16=2,0,0,0,84,3528,0,0,120,7200,0,0,35,625,0,0;QS=1,0;MQ0F=0 PL 0,6,77 17 1914 . C <*> 0 . DP=2;I16=2,0,0,0,82,3362,0,0,120,7200,0,0,37,697,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 1915 . T <*> 0 . DP=2;I16=2,0,0,0,64,2210,0,0,120,7200,0,0,39,773,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 1916 . G <*> 0 . DP=2;I16=2,0,0,0,75,2825,0,0,120,7200,0,0,41,853,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 1917 . C <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,43,937,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 1918 . A <*> 0 . DP=2;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 1919 . C <*> 0 . DP=2;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 1920 . A <*> 0 . DP=4;I16=2,2,0,0,109,3935,0,0,209,11641,0,0,54,1158,0,0;QS=1,0;MQ0F=0 PL 0,12,102 17 1921 . G <*> 0 . DP=4;I16=2,2,0,0,143,5193,0,0,209,11641,0,0,57,1219,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 1922 . T <*> 0 . DP=4;I16=2,2,0,0,152,5794,0,0,209,11641,0,0,60,1286,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 1923 . G <*> 0 . DP=4;I16=2,2,0,0,145,5317,0,0,209,11641,0,0,63,1359,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 1924 . C <*> 0 . DP=4;I16=2,2,0,0,127,4341,0,0,209,11641,0,0,65,1387,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 1925 . C <*> 0 . DP=4;I16=2,2,0,0,135,4869,0,0,209,11641,0,0,67,1419,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 1926 . T <*> 0 . DP=4;I16=2,2,0,0,160,6442,0,0,209,11641,0,0,69,1455,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 1927 . T <*> 0 . DP=4;I16=2,2,0,0,157,6179,0,0,209,11641,0,0,71,1495,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 1928 . C <*> 0 . DP=4;I16=2,2,0,0,146,5438,0,0,209,11641,0,0,73,1539,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 1929 . T <*> 0 . DP=4;I16=2,2,0,0,161,6525,0,0,209,11641,0,0,75,1587,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 1930 . G <*> 0 . DP=4;I16=2,2,0,0,123,4415,0,0,209,11641,0,0,77,1639,0,0;QS=1,0;MQ0F=0 PL 0,12,105 17 1931 . C <*> 0 . DP=4;I16=2,2,0,0,132,4686,0,0,209,11641,0,0,79,1695,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 1932 . T <*> 0 . DP=5;I16=2,3,0,0,164,5972,0,0,269,15241,0,0,81,1755,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 1933 . T <*> 0 . DP=5;I16=2,3,0,0,186,6958,0,0,269,15241,0,0,84,1820,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 1934 . G <*> 0 . DP=5;I16=2,3,0,0,173,6191,0,0,269,15241,0,0,87,1891,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 1935 . C <*> 0 . DP=5;I16=2,3,0,0,179,6539,0,0,269,15241,0,0,90,1968,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 1936 . C <*> 0 . DP=5;I16=2,3,0,0,181,6735,0,0,269,15241,0,0,93,2051,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 1937 . T <*> 0 . DP=5;I16=2,3,0,0,195,7741,0,0,269,15241,0,0,96,2140,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 1938 . G <*> 0 . DP=5;I16=2,3,0,0,176,6536,0,0,269,15241,0,0,99,2235,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 1939 . T C,<*> 0 . DP=5;I16=2,2,0,1,158,6250,3,9,240,14400,29,841,82,1924,19,361;QS=0.975309,0.0246914,0;SGB=-0.379885;RPBZ=-0.707107;MQBZ=-2;MQSBZ=-0.816497;BQBZ=-1.49071;SCBZ=-0.5;MQ0F=0 PL 0,8,138,12,141,138 17 1940 . G <*> 0 . DP=5;I16=2,3,0,0,177,6449,0,0,269,15241,0,0,103,2339,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 1941 . G <*> 0 . DP=5;I16=2,3,0,0,180,6620,0,0,269,15241,0,0,105,2397,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 1942 . C <*> 0 . DP=5;I16=2,3,0,0,161,5973,0,0,269,15241,0,0,107,2459,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 1943 . T <*> 0 . DP=5;I16=2,3,0,0,201,8119,0,0,269,15241,0,0,109,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 1944 . T <*> 0 . DP=5;I16=2,3,0,0,199,7983,0,0,269,15241,0,0,111,2595,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 1945 . T <*> 0 . DP=5;I16=2,3,0,0,200,8062,0,0,269,15241,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 1946 . G <*> 0 . DP=5;I16=2,3,0,0,188,7132,0,0,269,15241,0,0,114,2696,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 1947 . A <*> 0 . DP=5;I16=2,3,0,0,181,6939,0,0,269,15241,0,0,115,2725,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 1948 . G C,<*> 0 . DP=5;I16=2,2,0,1,150,5708,16,256,240,14400,29,841,91,2131,25,625;QS=0.903614,0.0963855,0;SGB=-0.379885;RPBZ=-0.707107;MQBZ=-2;MQSBZ=-0.816497;BQBZ=-1.41421;SCBZ=-0.5;MQ0F=0 PL 1,0,123,13,126,132 17 1949 . A <*> 0 . DP=5;I16=2,3,0,0,181,6599,0,0,269,15241,0,0,117,2789,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 1950 . A <*> 0 . DP=6;I16=2,4,0,0,222,8392,0,0,329,18841,0,0,118,2824,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 1951 . G <*> 0 . DP=6;I16=2,4,0,0,225,8533,0,0,329,18841,0,0,120,2862,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 1952 . A <*> 0 . DP=6;I16=2,4,0,0,219,8221,0,0,329,18841,0,0,122,2904,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 1953 . A <*> 0 . DP=6;I16=2,4,0,0,201,7161,0,0,329,18841,0,0,124,2950,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 1954 . A C,<*> 0 . DP=6;I16=2,3,0,1,166,5942,18,324,300,18000,29,841,101,2375,25,625;QS=0.902174,0.0978261,0;SGB=-0.379885;RPBZ=-0.29277;MQBZ=-2.23607;MQSBZ=-0.707107;BQBZ=-0.87831;SCBZ=-0.447214;MQ0F=0 PL 0,0,130,15,133,141 17 1955 . C <*> 0 . DP=6;I16=2,4,0,0,200,7332,0,0,329,18841,0,0,128,3054,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 1956 . C <*> 0 . DP=6;I16=2,4,0,0,191,7215,0,0,329,18841,0,0,130,3112,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 1957 . C G,<*> 0 . DP=6;I16=2,3,0,1,192,7426,7,49,300,18000,29,841,107,2549,25,625;QS=0.964824,0.0351759,0;SGB=-0.379885;RPBZ=-0.29277;MQBZ=-2.23607;MQSBZ=-0.707107;BQBZ=-1.48522;SCBZ=-0.447214;MQ0F=0 PL 0,9,159,15,162,161 17 1958 . C <*> 0 . DP=6;I16=2,4,0,0,234,9220,0,0,329,18841,0,0,133,3189,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 1959 . T <*> 0 . DP=6;I16=2,4,0,0,233,9255,0,0,329,18841,0,0,134,3206,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 1960 . T <*> 0 . DP=6;I16=2,4,0,0,227,8703,0,0,329,18841,0,0,135,3225,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 1961 . C <*> 0 . DP=6;I16=2,4,0,0,219,8327,0,0,329,18841,0,0,136,3246,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 1962 . T <*> 0 . DP=6;I16=2,4,0,0,248,10276,0,0,329,18841,0,0,137,3269,0,0;QS=1,0;MQ0F=0 PL 0,18,198 17 1963 . G <*> 0 . DP=6;I16=2,4,0,0,229,8867,0,0,329,18841,0,0,138,3294,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 1964 . G <*> 0 . DP=6;I16=2,4,0,0,202,7200,0,0,329,18841,0,0,139,3321,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 1965 . T <*> 0 . DP=6;I16=2,4,0,0,203,7523,0,0,329,18841,0,0,140,3350,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 1966 . T <*> 0 . DP=6;I16=2,4,0,0,218,8218,0,0,329,18841,0,0,141,3381,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 1967 . A <*> 0 . DP=6;I16=2,4,0,0,232,9056,0,0,329,18841,0,0,142,3414,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 1968 . T <*> 0 . DP=6;I16=2,4,0,0,242,9786,0,0,329,18841,0,0,143,3449,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 1969 . A <*> 0 . DP=6;I16=2,4,0,0,235,9247,0,0,329,18841,0,0,143,3437,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 1970 . C <*> 0 . DP=6;I16=2,4,0,0,220,8160,0,0,329,18841,0,0,143,3429,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 1971 . A <*> 0 . DP=7;I16=2,5,0,0,272,10634,0,0,389,22441,0,0,143,3425,0,0;QS=1,0;MQ0F=0 PL 0,21,206 17 1972 . T <*> 0 . DP=7;I16=2,5,0,0,260,9924,0,0,389,22441,0,0,144,3426,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 1973 . A <*> 0 . DP=7;I16=2,5,0,0,247,9695,0,0,389,22441,0,0,145,3433,0,0;QS=1,0;MQ0F=0 PL 0,21,197 17 1974 . A <*> 0 . DP=7;I16=2,5,0,0,278,11178,0,0,389,22441,0,0,145,3397,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 1975 . G <*> 0 . DP=7;I16=2,5,0,0,256,9422,0,0,389,22441,0,0,145,3369,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 1976 . A <*> 0 . DP=7;I16=2,5,0,0,261,9849,0,0,389,22441,0,0,144,3298,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 1977 . C <*> 0 . DP=7;I16=2,5,0,0,253,9303,0,0,389,22441,0,0,143,3233,0,0;QS=1,0;MQ0F=0 PL 0,21,194 17 1978 . A <*> 0 . DP=7;I16=2,5,0,0,294,12372,0,0,389,22441,0,0,142,3174,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 1979 . G <*> 0 . DP=7;I16=2,5,0,0,278,11068,0,0,389,22441,0,0,141,3121,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 1980 . C <*> 0 . DP=7;I16=2,5,0,0,254,9370,0,0,389,22441,0,0,140,3074,0,0;QS=1,0;MQ0F=0 PL 0,21,197 17 1981 . C <*> 0 . DP=8;I16=3,5,0,0,290,10896,0,0,449,26041,0,0,139,3033,0,0;QS=1,0;MQ0F=0 PL 0,24,219 17 1982 . A <*> 0 . DP=9;I16=4,5,0,0,342,13268,0,0,509,29641,0,0,139,2999,0,0;QS=1,0;MQ0F=0 PL 0,27,254 17 1983 . G <*> 0 . DP=9;I16=4,5,0,0,337,12781,0,0,509,29641,0,0,140,2974,0,0;QS=1,0;MQ0F=0 PL 0,27,249 17 1984 . A <*> 0 . DP=9;I16=4,5,0,0,355,14231,0,0,509,29641,0,0,141,2959,0,0;QS=1,0;MQ0F=0 PL 0,27,255 17 1985 . G <*> 0 . DP=9;I16=4,5,0,0,307,10921,0,0,509,29641,0,0,142,2954,0,0;QS=1,0;MQ0F=0 PL 0,27,231 17 1986 . A T,<*> 0 . DP=9;I16=4,4,0,1,287,10695,12,144,480,28800,29,841,118,2334,25,625;QS=0.959866,0.0401338,0;SGB=-0.379885;RPBZ=0.387298;MQBZ=-2.82843;MQSBZ=-0.894427;BQBZ=-1.55569;SCBZ=-0.53033;MQ0F=0 PL 0,14,213,24,216,217 17 1987 . A <*> 0 . DP=9;I16=4,5,0,0,333,12731,0,0,509,29641,0,0,144,2974,0,0;QS=1,0;MQ0F=0 PL 0,27,247 17 1988 . G <*> 0 . DP=9;I16=4,5,0,0,324,12106,0,0,509,29641,0,0,145,2999,0,0;QS=1,0;MQ0F=0 PL 0,27,239 17 1989 . G <*> 0 . DP=9;I16=4,5,0,0,322,12030,0,0,509,29641,0,0,145,2985,0,0;QS=1,0;MQ0F=0 PL 0,27,237 17 1990 . G T,<*> 0 . DP=9;I16=4,4,0,1,282,10212,33,1089,480,28800,29,841,120,2358,25,625;QS=0.906752,0.0932476,0;SGB=-0.379885;RPBZ=0.387298;MQBZ=-2.82843;MQSBZ=-0.894427;BQBZ=-0.58585;SCBZ=-0.53033;MQ0F=0 PL 2,0,195,26,198,215 17 1991 . A <*> 0 . DP=9;I16=4,5,0,0,335,13049,0,0,509,29641,0,0,145,2993,0,0;QS=1,0;MQ0F=0 PL 0,27,250 17 1992 . G <*> 0 . DP=9;I16=4,5,0,0,307,11009,0,0,509,29641,0,0,145,3015,0,0;QS=1,0;MQ0F=0 PL 0,27,231 17 1993 . T <*> 0 . DP=9;I16=4,5,0,0,344,13332,0,0,509,29641,0,0,145,3049,0,0;QS=1,0;MQ0F=0 PL 0,27,248 17 1994 . T <*> 0 . DP=8;I16=3,5,0,0,282,10256,0,0,449,26041,0,0,146,3094,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 1995 . G <*> 0 . DP=8;I16=3,5,0,0,237,8143,0,0,449,26041,0,0,147,3149,0,0;QS=1,0;MQ0F=0 PL 0,24,187 17 1996 . C <*> 0 . DP=8;I16=3,5,0,0,247,8121,0,0,449,26041,0,0,147,3165,0,0;QS=1,0;MQ0F=0 PL 0,24,192 17 1997 . C <*> 0 . DP=8;I16=3,5,0,0,248,8200,0,0,449,26041,0,0,146,3142,0,0;QS=1,0;MQ0F=0 PL 0,24,193 17 1998 . C <*> 0 . DP=8;I16=3,5,0,0,293,10963,0,0,449,26041,0,0,145,3129,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 1999 . A <*> 0 . DP=7;I16=2,5,0,0,276,11074,0,0,389,22441,0,0,145,3125,0,0;QS=1,0;MQ0F=0 PL 0,21,206 17 2000 . G <*> 0 . DP=7;I16=2,5,0,0,237,8811,0,0,389,22441,0,0,145,3129,0,0;QS=1,0;MQ0F=0 PL 0,21,178 17 2001 . G <*> 0 . DP=7;I16=2,5,0,0,226,8474,0,0,389,22441,0,0,145,3141,0,0;QS=1,0;MQ0F=0 PL 0,21,174 17 2002 . G <*> 0 . DP=7;I16=2,5,0,0,209,7217,0,0,389,22441,0,0,145,3161,0,0;QS=1,0;MQ0F=0 PL 0,21,166 17 2003 . T <*> 0 . DP=7;I16=2,5,0,0,242,8784,0,0,389,22441,0,0,145,3189,0,0;QS=1,0;MQ0F=0 PL 0,21,190 17 2004 . G <*> 0 . DP=7;I16=2,5,0,0,225,8173,0,0,389,22441,0,0,145,3225,0,0;QS=1,0;MQ0F=0 PL 0,21,179 17 2005 . G <*> 0 . DP=7;I16=2,5,0,0,199,6963,0,0,389,22441,0,0,145,3269,0,0;QS=1,0;MQ0F=0 PL 0,21,154 17 2006 . C <*> 0 . DP=7;I16=2,5,0,0,212,7468,0,0,389,22441,0,0,145,3321,0,0;QS=1,0;MQ0F=0 PL 0,21,167 17 2007 . A <*> 0 . DP=7;I16=2,5,0,0,249,9041,0,0,389,22441,0,0,144,3330,0,0;QS=1,0;MQ0F=0 PL 0,21,193 17 2008 . C <*> 0 . DP=7;I16=2,5,0,0,232,8210,0,0,389,22441,0,0,141,3245,0,0;QS=1,0;MQ0F=0 PL 0,21,183 17 2009 . A <*> 0 . DP=7;I16=2,5,0,0,266,10628,0,0,389,22441,0,0,138,3166,0,0;QS=1,0;MQ0F=0 PL 0,21,210 17 2010 . G C,<*> 0 . DP=7;I16=2,4,0,1,204,7382,10,100,360,21600,29,841,125,2993,10,100;QS=0.953271,0.046729,0;SGB=-0.379885;RPBZ=1;MQBZ=-2.44949;MQSBZ=-0.632456;BQBZ=-1.51357;SCBZ=-0.62361;MQ0F=0 PL 0,10,160,18,163,163 17 2011 . C T,<*> 0 . DP=7;I16=2,4,0,1,211,7627,6,36,360,21600,29,841,123,2945,9,81;QS=0.97235,0.0276498,0;SGB=-0.379885;RPBZ=1;MQBZ=-2.44949;MQSBZ=-0.632456;BQBZ=-1.51357;SCBZ=-0.62361;MQ0F=0 PL 0,12,168,18,171,168 17 2012 . A <*> 0 . DP=7;I16=2,5,0,0,239,8743,0,0,389,22441,0,0,129,2965,0,0;QS=1,0;MQ0F=0 PL 0,21,189 17 2013 . C <*> 0 . DP=7;I16=2,5,0,0,198,6510,0,0,389,22441,0,0,126,2910,0,0;QS=1,0;MQ0F=0 PL 0,21,159 17 2014 . G <*> 0 . DP=6;I16=2,4,0,0,195,6881,0,0,329,18841,0,0,124,2860,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 2015 . T <*> 0 . DP=6;I16=2,4,0,0,221,8381,0,0,329,18841,0,0,122,2814,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2016 . T <*> 0 . DP=6;I16=2,4,0,0,222,8338,0,0,329,18841,0,0,120,2772,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2017 . G <*> 0 . DP=6;I16=2,4,0,0,215,7999,0,0,329,18841,0,0,118,2734,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 2018 . C <*> 0 . DP=6;I16=2,4,0,0,202,7480,0,0,329,18841,0,0,116,2700,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 2019 . T <*> 0 . DP=6;I16=2,4,0,0,233,9103,0,0,329,18841,0,0,114,2670,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 2020 . G <*> 0 . DP=6;I16=2,4,0,0,212,7790,0,0,329,18841,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 2021 . C <*> 0 . DP=5;I16=2,3,0,0,192,7432,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 2022 . C <*> 0 . DP=6;I16=3,3,0,0,210,7490,0,0,360,21600,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 2023 . A <*> 0 . DP=6;I16=3,3,0,0,221,8457,0,0,360,21600,0,0,110,2582,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 2024 . G <*> 0 . DP=8;I16=4,4,0,0,258,8728,0,0,480,28800,0,0,110,2568,0,0;QS=1,0;MQ0F=0 PL 0,24,203 17 2025 . T <*> 0 . DP=8;I16=4,4,0,0,290,10752,0,0,480,28800,0,0,112,2560,0,0;QS=1,0;MQ0F=0 PL 0,24,226 17 2026 . T <*> 0 . DP=8;I16=4,4,0,0,267,9287,0,0,480,28800,0,0,113,2511,0,0;QS=1,0;MQ0F=0 PL 0,24,208 17 2027 . A <*> 0 . DP=8;I16=4,4,0,0,266,9614,0,0,480,28800,0,0,114,2472,0,0;QS=1,0;MQ0F=0 PL 0,24,210 17 2028 . C <*> 0 . DP=8;I16=4,4,0,0,293,10887,0,0,480,28800,0,0,115,2443,0,0;QS=1,0;MQ0F=0 PL 0,24,228 17 2029 . T <*> 0 . DP=8;I16=4,4,0,0,306,11824,0,0,480,28800,0,0,116,2424,0,0;QS=1,0;MQ0F=0 PL 0,24,236 17 2030 . G <*> 0 . DP=8;I16=4,4,0,0,278,9842,0,0,480,28800,0,0,117,2415,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 2031 . C <*> 0 . DP=8;I16=4,4,0,0,262,8824,0,0,480,28800,0,0,118,2416,0,0;QS=1,0;MQ0F=0 PL 0,24,204 17 2032 . C <*> 0 . DP=8;I16=4,4,0,0,268,9364,0,0,480,28800,0,0,119,2427,0,0;QS=1,0;MQ0F=0 PL 0,24,210 17 2033 . A <*> 0 . DP=7;I16=4,3,0,0,254,9280,0,0,420,25200,0,0,121,2447,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 2034 . T <*> 0 . DP=7;I16=4,3,0,0,257,9659,0,0,420,25200,0,0,123,2475,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 2035 . T <*> 0 . DP=7;I16=4,3,0,0,260,10046,0,0,420,25200,0,0,125,2511,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 2036 . T <*> 0 . DP=7;I16=4,3,0,0,268,10428,0,0,420,25200,0,0,127,2555,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 2037 . T <*> 0 . DP=7;I16=4,3,0,0,271,10557,0,0,420,25200,0,0,129,2607,0,0;QS=1,0;MQ0F=0 PL 0,21,217 17 2038 . C <*> 0 . DP=7;I16=4,3,0,0,262,9910,0,0,420,25200,0,0,131,2667,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 2039 . A <*> 0 . DP=7;I16=4,3,0,0,265,10071,0,0,420,25200,0,0,133,2735,0,0;QS=1,0;MQ0F=0 PL 0,21,212 17 2040 . C <*> 0 . DP=7;I16=4,3,0,0,243,8635,0,0,420,25200,0,0,135,2811,0,0;QS=1,0;MQ0F=0 PL 0,21,196 17 2041 . G A,<*> 0 . DP=7;I16=0,0,4,3,0,0,276,11066,0,0,420,25200,0,0,137,2895;QS=0,1,0;VDB=0.792147;SGB=-0.636426;MQSBZ=0;MQ0F=0 PL 223,21,0,223,21,223 17 2042 . G <*> 0 . DP=7;I16=4,3,0,0,256,9542,0,0,420,25200,0,0,139,2987,0,0;QS=1,0;MQ0F=0 PL 0,21,206 17 2043 . G <*> 0 . DP=7;I16=4,3,0,0,240,8782,0,0,420,25200,0,0,141,3087,0,0;QS=1,0;MQ0F=0 PL 0,21,197 17 2044 . C <*> 0 . DP=7;I16=4,3,0,0,258,9636,0,0,420,25200,0,0,143,3195,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 2045 . A <*> 0 . DP=7;I16=4,3,0,0,267,10223,0,0,420,25200,0,0,145,3311,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 2046 . T <*> 0 . DP=7;I16=4,3,0,0,272,10582,0,0,420,25200,0,0,147,3435,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 2047 . G <*> 0 . DP=7;I16=4,3,0,0,244,9242,0,0,420,25200,0,0,148,3518,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 2048 . A <*> 0 . DP=7;I16=4,3,0,0,256,9586,0,0,420,25200,0,0,148,3560,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 2049 . A <*> 0 . DP=7;I16=4,3,0,0,265,10057,0,0,420,25200,0,0,148,3610,0,0;QS=1,0;MQ0F=0 PL 0,21,210 17 2050 . A <*> 0 . DP=7;I16=4,3,0,0,235,8619,0,0,420,25200,0,0,146,3566,0,0;QS=1,0;MQ0F=0 PL 0,21,193 17 2051 . T <*> 0 . DP=6;I16=4,2,0,0,204,7382,0,0,360,21600,0,0,145,3525,0,0;QS=1,0;MQ0F=0 PL 0,18,170 17 2052 . G <*> 0 . DP=6;I16=4,2,0,0,211,7615,0,0,360,21600,0,0,144,3486,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 2053 . G <*> 0 . DP=6;I16=4,2,0,0,219,8091,0,0,360,21600,0,0,143,3449,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 2054 . A <*> 0 . DP=6;I16=4,2,0,0,203,7377,0,0,360,21600,0,0,142,3414,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 2055 . G <*> 0 . DP=6;I16=4,2,0,0,203,7071,0,0,360,21600,0,0,141,3381,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 2056 . A <*> 0 . DP=6;I16=4,2,0,0,219,8059,0,0,360,21600,0,0,140,3350,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 2057 . T <*> 0 . DP=6;I16=4,2,0,0,219,8015,0,0,360,21600,0,0,138,3272,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2058 . A <*> 0 . DP=6;I16=4,2,0,0,217,7929,0,0,360,21600,0,0,135,3149,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 2059 . A <*> 0 . DP=6;I16=4,2,0,0,224,8446,0,0,360,21600,0,0,132,3032,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 2060 . C G,<*> 0 . DP=6;I16=3,2,1,0,162,5622,2,4,300,18000,60,3600,107,2437,22,484;QS=0.975904,0.0240964,0;SGB=-0.379885;RPBZ=1.48522;MQBZ=0;MQSBZ=0;BQBZ=-1.46385;SCBZ=1.73205;MQ0F=0 PL 0,10,137,15,140,137 17 2061 . A <*> 0 . DP=5;I16=3,2,0,0,187,7029,0,0,300,18000,0,0,105,2375,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 2062 . A <*> 0 . DP=5;I16=3,2,0,0,187,7195,0,0,300,18000,0,0,103,2317,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 2063 . C <*> 0 . DP=5;I16=3,2,0,0,182,6678,0,0,300,18000,0,0,101,2263,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 2064 . A <*> 0 . DP=5;I16=3,2,0,0,188,7154,0,0,300,18000,0,0,99,2213,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 2065 . G <*> 0 . DP=6;I16=4,2,0,0,204,7038,0,0,360,21600,0,0,97,2167,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 2066 . G <*> 0 . DP=6;I16=4,2,0,0,184,5774,0,0,360,21600,0,0,96,2126,0,0;QS=1,0;MQ0F=0 PL 0,18,152 17 2067 . A <*> 0 . DP=6;I16=4,2,0,0,228,8744,0,0,360,21600,0,0,95,2091,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 2068 . G <*> 0 . DP=6;I16=4,2,0,0,201,7049,0,0,360,21600,0,0,94,2062,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 2069 . C <*> 0 . DP=6;I16=4,2,0,0,191,6207,0,0,360,21600,0,0,93,2039,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 2070 . G <*> 0 . DP=6;I16=4,2,0,0,178,5370,0,0,360,21600,0,0,92,2022,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 2071 . A <*> 0 . DP=6;I16=4,2,0,0,216,7856,0,0,360,21600,0,0,91,2011,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 2072 . C <*> 0 . DP=5;I16=4,1,0,0,157,4971,0,0,300,18000,0,0,91,2005,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 2073 . C <*> 0 . DP=5;I16=4,1,0,0,161,5287,0,0,300,18000,0,0,91,2003,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2074 . G <*> 0 . DP=5;I16=4,1,0,0,104,2430,0,0,300,18000,0,0,91,2005,0,0;QS=1,0;MQ0F=0 PL 0,15,87 17 2075 . C <*> 0 . DP=5;I16=4,1,0,0,138,3910,0,0,300,18000,0,0,91,2011,0,0;QS=1,0;MQ0F=0 PL 0,15,113 17 2076 . A G,<*> 0 . DP=5;I16=3,1,1,0,130,4242,1,1,240,14400,60,3600,80,1900,11,121;QS=0.970149,0.0298507,0;SGB=-0.379885;RPBZ=-1.45095;MQBZ=0;MQSBZ=0;BQBZ=-1.45095;SCBZ=-0.5;MQ0F=0 PL 0,8,108,12,111,108 17 2077 . C <*> 0 . DP=5;I16=4,1,0,0,150,4766,0,0,300,18000,0,0,91,2035,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 2078 . A <*> 0 . DP=5;I16=4,1,0,0,180,6606,0,0,300,18000,0,0,91,2053,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 2079 . G <*> 0 . DP=5;I16=4,1,0,0,160,5324,0,0,300,18000,0,0,91,2075,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2080 . G <*> 0 . DP=5;I16=4,1,0,0,122,3820,0,0,300,18000,0,0,91,2101,0,0;QS=1,0;MQ0F=0 PL 0,15,107 17 2081 . C <*> 0 . DP=5;I16=4,1,0,0,132,3710,0,0,300,18000,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,15,110 17 2082 . T <*> 0 . DP=4;I16=3,1,0,0,125,4087,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 2083 . G <*> 0 . DP=4;I16=3,1,0,0,127,4195,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2084 . C <*> 0 . DP=4;I16=3,1,0,0,131,4365,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 2085 . T <*> 0 . DP=4;I16=3,1,0,0,147,5477,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 2086 . G <*> 0 . DP=4;I16=3,1,0,0,147,5449,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2087 . A <*> 0 . DP=4;I16=3,1,0,0,143,5207,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2088 . G <*> 0 . DP=4;I16=3,1,0,0,137,4767,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 2089 . C <*> 0 . DP=5;I16=4,1,0,0,168,5664,0,0,300,18000,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,15,138 17 2090 . G <*> 0 . DP=5;I16=4,1,0,0,118,3330,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,101 17 2091 . C <*> 0 . DP=5;I16=4,1,0,0,152,4822,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 2092 . G <*> 0 . DP=6;I16=5,1,0,0,172,5180,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,133 17 2093 . T <*> 0 . DP=6;I16=5,1,0,0,195,6697,0,0,360,21600,0,0,105,2517,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 2094 . C <*> 0 . DP=6;I16=5,1,0,0,185,5827,0,0,360,21600,0,0,107,2529,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 2095 . A <*> 0 . DP=6;I16=5,1,0,0,202,6892,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 2096 . C <*> 0 . DP=6;I16=5,1,0,0,214,7660,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 2097 . A <*> 0 . DP=6;I16=5,1,0,0,228,8686,0,0,360,21600,0,0,113,2589,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 2098 . C <*> 0 . DP=6;I16=5,1,0,0,182,5678,0,0,360,21600,0,0,114,2568,0,0;QS=1,0;MQ0F=0 PL 0,18,139 17 2099 . G <*> 0 . DP=6;I16=5,1,0,0,168,4910,0,0,360,21600,0,0,115,2553,0,0;QS=1,0;MQ0F=0 PL 0,18,129 17 2100 . C <*> 0 . DP=6;I16=5,1,0,0,208,7382,0,0,360,21600,0,0,114,2446,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 2101 . A <*> 0 . DP=6;I16=5,1,0,0,210,7502,0,0,360,21600,0,0,113,2349,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 2102 . G <*> 0 . DP=6;I16=5,1,0,0,192,6478,0,0,360,21600,0,0,112,2262,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 2103 . C <*> 0 . DP=6;I16=5,1,0,0,177,6371,0,0,360,21600,0,0,111,2185,0,0;QS=1,0;MQ0F=0 PL 0,18,145 17 2104 . C <*> 0 . DP=5;I16=4,1,0,0,178,6450,0,0,300,18000,0,0,92,1794,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2105 . A <*> 0 . DP=5;I16=4,1,0,0,159,5155,0,0,300,18000,0,0,92,1772,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 2106 . T <*> 0 . DP=5;I16=4,1,0,0,180,6500,0,0,300,18000,0,0,92,1758,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 2107 . C <*> 0 . DP=5;I16=4,1,0,0,162,5414,0,0,300,18000,0,0,92,1752,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2108 . G <*> 0 . DP=5;I16=4,1,0,0,133,3807,0,0,300,18000,0,0,92,1754,0,0;QS=1,0;MQ0F=0 PL 0,15,111 17 2109 . C <*> 0 . DP=5;I16=4,1,0,0,154,5166,0,0,300,18000,0,0,92,1764,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 2110 . G <*> 0 . DP=5;I16=4,1,0,0,140,4176,0,0,300,18000,0,0,92,1782,0,0;QS=1,0;MQ0F=0 PL 0,15,117 17 2111 . C <*> 0 . DP=5;I16=4,1,0,0,170,5932,0,0,300,18000,0,0,92,1808,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2112 . A <*> 0 . DP=5;I16=4,1,0,0,168,5954,0,0,300,18000,0,0,92,1842,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2113 . G <*> 0 . DP=5;I16=4,1,0,0,159,5407,0,0,300,18000,0,0,92,1884,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2114 . C <*> 0 . DP=5;I16=4,1,0,0,150,5014,0,0,300,18000,0,0,92,1934,0,0;QS=1,0;MQ0F=0 PL 0,15,126 17 2115 . T <*> 0 . DP=5;I16=4,1,0,0,174,6196,0,0,300,18000,0,0,91,1941,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 2116 . C <*> 0 . DP=5;I16=4,1,0,0,185,6931,0,0,300,18000,0,0,90,1954,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 2117 . A <*> 0 . DP=5;I16=4,1,0,0,191,7373,0,0,300,18000,0,0,89,1973,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 2118 . G <*> 0 . DP=5;I16=4,1,0,0,179,6497,0,0,300,18000,0,0,87,1947,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2119 . G <*> 0 . DP=5;I16=4,1,0,0,164,5642,0,0,300,18000,0,0,85,1925,0,0;QS=1,0;MQ0F=0 PL 0,15,137 17 2120 . G <*> 0 . DP=5;I16=4,1,0,0,171,5947,0,0,300,18000,0,0,83,1907,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2121 . A <*> 0 . DP=5;I16=4,1,0,0,142,4906,0,0,300,18000,0,0,81,1893,0,0;QS=1,0;MQ0F=0 PL 0,15,123 17 2122 . T <*> 0 . DP=5;I16=4,1,0,0,149,5043,0,0,300,18000,0,0,79,1883,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 2123 . A <*> 0 . DP=5;I16=4,1,0,0,166,5692,0,0,300,18000,0,0,77,1877,0,0;QS=1,0;MQ0F=0 PL 0,15,137 17 2124 . T <*> 0 . DP=5;I16=4,1,0,0,175,6187,0,0,300,18000,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 2125 . T <*> 0 . DP=3;I16=3,0,0,0,110,4094,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 2126 . A <*> 0 . DP=3;I16=3,0,0,0,113,4281,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 2127 . C <*> 0 . DP=3;I16=3,0,0,0,113,4275,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 2128 . G <*> 0 . DP=3;I16=3,0,0,0,84,2478,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 2129 . T <*> 0 . DP=3;I16=3,0,0,0,98,3286,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,83 17 2130 . G <*> 0 . DP=3;I16=3,0,0,0,101,3609,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,87 17 2131 . T <*> 0 . DP=3;I16=3,0,0,0,91,3025,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,79 17 2132 . A <*> 0 . DP=3;I16=3,0,0,0,104,3678,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2133 . A <*> 0 . DP=3;I16=3,0,0,0,113,4331,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 2134 . C <*> 0 . DP=3;I16=3,0,0,0,102,3546,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,86 17 2135 . T <*> 0 . DP=4;I16=3,1,0,0,132,4682,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 2136 . C <*> 0 . DP=4;I16=3,1,0,0,144,5314,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 2137 . G <*> 0 . DP=4;I16=3,1,0,0,114,3426,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,102 17 2138 . A <*> 0 . DP=4;I16=3,1,0,0,159,6337,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2139 . C <*> 0 . DP=4;I16=3,1,0,0,143,5143,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2140 . A <*> 0 . DP=4;I16=3,1,0,0,157,6171,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 2141 . T <*> 0 . DP=4;I16=3,1,0,0,156,6098,0,0,240,14400,0,0,80,1862,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 2142 . G <*> 0 . DP=4;I16=3,1,0,0,145,5349,0,0,240,14400,0,0,80,1828,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2143 . T <*> 0 . DP=4;I16=3,1,0,0,134,4698,0,0,240,14400,0,0,80,1798,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 2144 . C <*> 0 . DP=4;I16=3,1,0,0,141,5065,0,0,240,14400,0,0,80,1772,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2145 . A <*> 0 . DP=4;I16=3,1,0,0,158,6300,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2146 . G <*> 0 . DP=4;I16=3,1,0,0,144,5242,0,0,240,14400,0,0,80,1732,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 2147 . C <*> 0 . DP=5;I16=3,2,0,0,150,5506,0,0,300,18000,0,0,82,1722,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 2148 . G <*> 0 . DP=5;I16=3,2,0,0,137,4241,0,0,300,18000,0,0,83,1717,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 2149 . A <*> 0 . DP=5;I16=3,2,0,0,150,5030,0,0,300,18000,0,0,84,1718,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2150 . T <*> 0 . DP=5;I16=3,2,0,0,157,5265,0,0,300,18000,0,0,85,1725,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 2151 . T <*> 0 . DP=5;I16=3,2,0,0,163,5451,0,0,300,18000,0,0,86,1738,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2152 . G <*> 0 . DP=5;I16=3,2,0,0,168,5774,0,0,300,18000,0,0,87,1757,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 2153 . T <*> 0 . DP=5;I16=3,2,0,0,186,7002,0,0,300,18000,0,0,88,1782,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 2154 . C <*> 0 . DP=5;I16=3,2,0,0,183,6803,0,0,300,18000,0,0,89,1813,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 2155 . A <*> 0 . DP=5;I16=3,2,0,0,179,6639,0,0,300,18000,0,0,90,1850,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 2156 . C <*> 0 . DP=5;I16=3,2,0,0,177,6331,0,0,300,18000,0,0,91,1893,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 2157 . A <*> 0 . DP=5;I16=3,2,0,0,199,7987,0,0,300,18000,0,0,92,1942,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 2158 . G <*> 0 . DP=5;I16=3,2,0,0,163,5717,0,0,300,18000,0,0,93,1997,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 2159 . G <*> 0 . DP=5;I16=3,2,0,0,174,6250,0,0,300,18000,0,0,94,2058,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 2160 . C <*> 0 . DP=5;I16=3,2,0,0,177,6351,0,0,300,18000,0,0,95,2125,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 2161 . A <*> 0 . DP=5;I16=3,2,0,0,189,7189,0,0,300,18000,0,0,95,2147,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 2162 . C <*> 0 . DP=5;I16=3,2,0,0,179,6435,0,0,300,18000,0,0,95,2173,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 2163 . T <*> 0 . DP=5;I16=3,2,0,0,202,8204,0,0,300,18000,0,0,95,2203,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 2164 . G <*> 0 . DP=5;I16=3,2,0,0,179,6519,0,0,300,18000,0,0,95,2237,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 2165 . C <*> 0 . DP=5;I16=3,2,0,0,173,6199,0,0,300,18000,0,0,94,2226,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 2166 . T <*> 0 . DP=4;I16=2,2,0,0,152,5976,0,0,240,14400,0,0,94,2220,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 2167 . A G,<*> 0 . DP=4;I16=2,1,0,1,117,4565,7,49,180,10800,60,3600,72,1734,22,484;QS=0.943548,0.0564516,0;SGB=-0.379885;RPBZ=-1.34164;MQBZ=0;MQSBZ=0;BQBZ=-1.34164;SCBZ=1.73205;MQ0F=0 PL 0,4,103,9,106,105 17 2168 . C <*> 0 . DP=4;I16=2,2,0,0,135,4671,0,0,240,14400,0,0,93,2171,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2169 . T <*> 0 . DP=4;I16=2,2,0,0,154,6034,0,0,240,14400,0,0,92,2130,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 2170 . C <*> 0 . DP=4;I16=2,2,0,0,147,5435,0,0,240,14400,0,0,91,2095,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 2171 . C <*> 0 . DP=4;I16=2,2,0,0,151,5739,0,0,240,14400,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 2172 . T <*> 0 . DP=4;I16=2,2,0,0,160,6470,0,0,240,14400,0,0,87,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,147 17 2173 . G <*> 0 . DP=4;I16=2,2,0,0,145,5397,0,0,240,14400,0,0,85,1867,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 2174 . G <*> 0 . DP=4;I16=2,2,0,0,140,5094,0,0,240,14400,0,0,83,1799,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2175 . G <*> 0 . DP=4;I16=2,2,0,0,137,4869,0,0,240,14400,0,0,81,1735,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2176 . G <*> 0 . DP=4;I16=2,2,0,0,134,4622,0,0,240,14400,0,0,79,1675,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 2177 . T <*> 0 . DP=4;I16=2,2,0,0,116,3850,0,0,240,14400,0,0,77,1619,0,0;QS=1,0;MQ0F=0 PL 0,12,108 17 2178 . T <*> 0 . DP=4;I16=2,2,0,0,127,4439,0,0,240,14400,0,0,75,1567,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 2179 . T <*> 0 . DP=4;I16=2,2,0,0,147,5507,0,0,240,14400,0,0,73,1519,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 2180 . T <*> 0 . DP=4;I16=2,2,0,0,145,5331,0,0,240,14400,0,0,71,1475,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 2181 . C <*> 0 . DP=4;I16=2,2,0,0,164,6736,0,0,240,14400,0,0,69,1435,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 2182 . C <*> 0 . DP=4;I16=2,2,0,0,159,6335,0,0,240,14400,0,0,67,1399,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 2183 . A <*> 0 . DP=4;I16=2,2,0,0,157,6197,0,0,240,14400,0,0,65,1367,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 2184 . T <*> 0 . DP=4;I16=2,2,0,0,148,5566,0,0,240,14400,0,0,63,1339,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 2185 . C <*> 0 . DP=4;I16=2,2,0,0,149,5607,0,0,240,14400,0,0,61,1315,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 2186 . A <*> 0 . DP=4;I16=2,2,0,0,159,6335,0,0,240,14400,0,0,59,1295,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 2187 . A <*> 0 . DP=4;I16=2,2,0,0,148,5498,0,0,240,14400,0,0,57,1279,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 2188 . A <*> 0 . DP=4;I16=2,2,0,0,135,4593,0,0,240,14400,0,0,55,1267,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 2189 . C <*> 0 . DP=5;I16=2,3,0,0,166,5678,0,0,300,18000,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 2190 . C <*> 0 . DP=4;I16=1,3,0,0,120,3974,0,0,240,14400,0,0,53,1255,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 2191 . C <*> 0 . DP=4;I16=1,3,0,0,134,4692,0,0,240,14400,0,0,53,1255,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 2192 . T <*> 0 . DP=4;I16=1,3,0,0,137,4967,0,0,240,14400,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 2193 . C <*> 0 . DP=3;I16=0,3,0,0,101,3617,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,87 17 2194 . A <*> 0 . DP=3;I16=0,3,0,0,117,4577,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2195 . A <*> 0 . DP=3;I16=0,3,0,0,119,4789,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 2196 . G <*> 0 . DP=4;I16=0,4,0,0,155,6041,0,0,240,14400,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 2197 . A <*> 0 . DP=4;I16=0,4,0,0,162,6602,0,0,240,14400,0,0,59,1315,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2198 . G <*> 0 . DP=4;I16=0,4,0,0,134,4844,0,0,240,14400,0,0,61,1335,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 2199 . C <*> 0 . DP=4;I16=0,4,0,0,150,5670,0,0,240,14400,0,0,63,1359,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 2200 . T <*> 0 . DP=4;I16=0,4,0,0,147,5439,0,0,240,14400,0,0,65,1387,0,0;QS=1,0;MQ0F=0 PL 0,12,114 17 2201 . G <*> 0 . DP=4;I16=0,4,0,0,154,5964,0,0,240,14400,0,0,67,1419,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 2202 . G <*> 0 . DP=4;I16=0,4,0,0,148,5532,0,0,240,14400,0,0,69,1455,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 2203 . G <*> 0 . DP=4;I16=0,4,0,0,149,5637,0,0,240,14400,0,0,71,1495,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 2204 . C <*> 0 . DP=4;I16=0,4,0,0,124,4134,0,0,240,14400,0,0,73,1539,0,0;QS=1,0;MQ0F=0 PL 0,12,99 17 2205 . C <*> 0 . DP=4;I16=0,4,0,0,139,4963,0,0,240,14400,0,0,75,1587,0,0;QS=1,0;MQ0F=0 PL 0,12,109 17 2206 . T <*> 0 . DP=4;I16=0,4,0,0,149,5577,0,0,240,14400,0,0,77,1639,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 2207 . G <*> 0 . DP=4;I16=0,4,0,0,141,5085,0,0,240,14400,0,0,79,1695,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 2208 . G <*> 0 . DP=4;I16=0,4,0,0,158,6282,0,0,240,14400,0,0,81,1755,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 2209 . G <*> 0 . DP=4;I16=0,4,0,0,151,5751,0,0,240,14400,0,0,83,1819,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2210 . G <*> 0 . DP=4;I16=0,4,0,0,145,5315,0,0,240,14400,0,0,85,1887,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2211 . T <*> 0 . DP=4;I16=0,4,0,0,162,6570,0,0,240,14400,0,0,86,1910,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2212 . C <*> 0 . DP=4;I16=0,4,0,0,143,5177,0,0,240,14400,0,0,87,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 2213 . A <*> 0 . DP=4;I16=0,4,0,0,144,5250,0,0,240,14400,0,0,88,1974,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 2214 . A <*> 0 . DP=4;I16=0,4,0,0,150,5708,0,0,240,14400,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2215 . C <*> 0 . DP=4;I16=0,4,0,0,160,6444,0,0,240,14400,0,0,89,2011,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2216 . T <*> 0 . DP=4;I16=0,4,0,0,158,6356,0,0,240,14400,0,0,89,2011,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2217 . T <*> 0 . DP=4;I16=0,4,0,0,150,5810,0,0,240,14400,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 2218 . C <*> 0 . DP=4;I16=0,4,0,0,154,5950,0,0,240,14400,0,0,89,2023,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 2219 . C <*> 0 . DP=4;I16=0,4,0,0,159,6331,0,0,240,14400,0,0,89,2035,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 2220 . G A,<*> 0 . DP=4;I16=0,0,0,4,0,0,170,7254,0,0,240,14400,0,0,89,2051;QS=0,1,0;VDB=0.756056;SGB=-0.556411;MQ0F=0 PL 131,12,0,131,12,131 17 2221 . G <*> 0 . DP=4;I16=0,4,0,0,154,6054,0,0,240,14400,0,0,88,2022,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 2222 . C <*> 0 . DP=4;I16=0,4,0,0,133,4857,0,0,240,14400,0,0,86,1948,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 2223 . C <*> 0 . DP=4;I16=0,4,0,0,158,6262,0,0,240,14400,0,0,84,1878,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 2224 . T <*> 0 . DP=4;I16=0,4,0,0,160,6424,0,0,240,14400,0,0,82,1812,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 2225 . G <*> 0 . DP=4;I16=0,4,0,0,157,6195,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 2226 . G <*> 0 . DP=4;I16=0,4,0,0,145,5349,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2227 . G <*> 0 . DP=4;I16=0,4,0,0,146,5406,0,0,240,14400,0,0,76,1638,0,0;QS=1,0;MQ0F=0 PL 0,12,114 17 2228 . G <*> 0 . DP=4;I16=0,4,0,0,156,6128,0,0,240,14400,0,0,74,1588,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 2229 . A <*> 0 . DP=4;I16=0,4,0,0,158,6274,0,0,240,14400,0,0,72,1542,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 2230 . A <*> 0 . DP=4;I16=0,4,0,0,153,5909,0,0,240,14400,0,0,70,1500,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 2231 . A <*> 0 . DP=4;I16=0,4,0,0,161,6493,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2232 . C <*> 0 . DP=4;I16=0,4,0,0,136,4778,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 2233 . T <*> 0 . DP=4;I16=0,4,0,0,151,5737,0,0,240,14400,0,0,64,1398,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2234 . G <*> 0 . DP=4;I16=0,4,0,0,143,5211,0,0,240,14400,0,0,62,1372,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 2235 . G <*> 0 . DP=4;I16=0,4,0,0,138,4946,0,0,240,14400,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,12,109 17 2236 . G <*> 0 . DP=3;I16=0,3,0,0,98,3410,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 2237 . G <*> 0 . DP=3;I16=0,3,0,0,100,3686,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,86 17 2238 . C <*> 0 . DP=3;I16=0,3,0,0,90,3012,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 2239 . A <*> 0 . DP=3;I16=0,3,0,0,95,3649,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,83 17 2240 . A <*> 0 . DP=3;I16=0,3,0,0,120,4842,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 2241 . G <*> 0 . DP=3;I16=0,3,0,0,103,3701,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2242 . T <*> 0 . DP=3;I16=0,3,0,0,113,4275,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 2243 . A <*> 0 . DP=3;I16=0,3,0,0,118,4658,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2244 . T <*> 0 . DP=3;I16=0,3,0,0,116,4574,0,0,180,10800,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2245 . C <*> 0 . DP=3;I16=0,3,0,0,103,3765,0,0,180,10800,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2246 . A <*> 0 . DP=2;I16=0,2,0,0,79,3133,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 2247 . C <*> 0 . DP=2;I16=0,2,0,0,78,3050,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 2248 . C <*> 0 . DP=2;I16=0,2,0,0,82,3362,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2249 . A <*> 0 . DP=2;I16=0,2,0,0,88,3872,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 2250 . G <*> 0 . DP=2;I16=0,2,0,0,86,3698,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,78 17 2251 . A <*> 0 . DP=2;I16=0,2,0,0,88,3872,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 2252 . G <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2253 . A <*> 0 . DP=2;I16=0,2,0,0,80,3200,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2254 . T <*> 0 . DP=2;I16=0,2,0,0,80,3200,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2255 . G <*> 0 . DP=2;I16=0,2,0,0,77,2977,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,71 17 2256 . A <*> 0 . DP=2;I16=0,2,0,0,85,3617,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,78 17 2257 . G <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 2258 . C <*> 0 . DP=2;I16=0,2,0,0,76,2920,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2259 . T <*> 0 . DP=2;I16=0,2,0,0,87,3785,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,79 17 2260 . T <*> 0 . DP=2;I16=0,2,0,0,78,3074,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 2261 . T <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2262 . A <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 2263 . T <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 2264 . A <*> 0 . DP=2;I16=0,2,0,0,82,3364,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2265 . A <*> 0 . DP=2;I16=0,2,0,0,82,3362,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2266 . A <*> 0 . DP=2;I16=0,2,0,0,82,3364,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2267 . A <*> 0 . DP=3;I16=1,2,0,0,114,4370,0,0,180,10800,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 2268 . A <*> 0 . DP=3;I16=1,2,0,0,116,4498,0,0,180,10800,0,0,47,1067,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 2269 . T <*> 0 . DP=3;I16=1,2,0,0,117,4571,0,0,180,10800,0,0,47,1029,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 2270 . A <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,47,995,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 2271 . A <*> 0 . DP=3;I16=1,2,0,0,118,4644,0,0,180,10800,0,0,47,965,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 2272 . T <*> 0 . DP=3;I16=1,2,0,0,118,4646,0,0,180,10800,0,0,46,890,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 2273 . G <*> 0 . DP=3;I16=1,2,0,0,122,4966,0,0,180,10800,0,0,45,821,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 2274 . G <*> 0 . DP=3;I16=1,2,0,0,116,4490,0,0,180,10800,0,0,44,758,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 2275 . T <*> 0 . DP=3;I16=1,2,0,0,120,4802,0,0,180,10800,0,0,43,701,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 2276 . G <*> 0 . DP=4;I16=2,2,0,0,122,4596,0,0,240,14400,0,0,42,650,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2277 . C <*> 0 . DP=4;I16=2,2,0,0,152,5796,0,0,240,14400,0,0,42,606,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2278 . T <*> 0 . DP=4;I16=2,2,0,0,162,6570,0,0,240,14400,0,0,42,570,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 2279 . A <*> 0 . DP=4;I16=2,2,0,0,157,6177,0,0,240,14400,0,0,42,542,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 2280 . G <*> 0 . DP=4;I16=2,2,0,0,158,6250,0,0,240,14400,0,0,42,522,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 2281 . C <*> 0 . DP=4;I16=2,2,0,0,153,5879,0,0,240,14400,0,0,42,510,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 2282 . T <*> 0 . DP=4;I16=2,2,0,0,164,6740,0,0,240,14400,0,0,42,506,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 2283 . G <*> 0 . DP=4;I16=2,2,0,0,155,6015,0,0,240,14400,0,0,42,510,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 2284 . G <*> 0 . DP=4;I16=2,2,0,0,154,5946,0,0,240,14400,0,0,42,522,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 2285 . G <*> 0 . DP=4;I16=2,2,0,0,158,6254,0,0,240,14400,0,0,42,542,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 2286 . C <*> 0 . DP=4;I16=2,2,0,0,141,5075,0,0,240,14400,0,0,42,570,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 2287 . A <*> 0 . DP=4;I16=2,2,0,0,156,6094,0,0,240,14400,0,0,42,606,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 2288 . T <*> 0 . DP=4;I16=2,2,0,0,156,6086,0,0,240,14400,0,0,42,650,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 2289 . G <*> 0 . DP=4;I16=2,2,0,0,138,4860,0,0,240,14400,0,0,42,702,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2290 . G <*> 0 . DP=3;I16=2,1,0,0,121,4909,0,0,180,10800,0,0,43,761,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 2291 . T <*> 0 . DP=3;I16=2,1,0,0,119,4721,0,0,180,10800,0,0,44,826,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 2292 . G <*> 0 . DP=3;I16=2,1,0,0,115,4417,0,0,180,10800,0,0,45,897,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 2293 . G <*> 0 . DP=3;I16=2,1,0,0,119,4733,0,0,180,10800,0,0,45,923,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 2294 . C <*> 0 . DP=3;I16=2,1,0,0,121,4899,0,0,180,10800,0,0,45,953,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 2295 . T <*> 0 . DP=3;I16=2,1,0,0,122,5010,0,0,180,10800,0,0,45,987,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 2296 . T <*> 0 . DP=3;I16=2,1,0,0,113,4345,0,0,180,10800,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 2297 . G <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 2298 . C <*> 0 . DP=3;I16=2,1,0,0,113,4349,0,0,180,10800,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 2299 . A <*> 0 . DP=3;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,49,1155,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 2300 . C <*> 0 . DP=3;I16=2,1,0,0,116,4506,0,0,180,10800,0,0,51,1205,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 2301 . C <*> 0 . DP=4;I16=2,2,0,0,125,5071,0,0,240,14400,0,0,55,1263,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2302 . T <*> 0 . DP=4;I16=2,2,0,0,158,6330,0,0,240,14400,0,0,57,1275,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 2303 . G <*> 0 . DP=4;I16=2,2,0,0,152,5838,0,0,240,14400,0,0,59,1291,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2304 . T <*> 0 . DP=4;I16=2,2,0,0,153,5891,0,0,240,14400,0,0,61,1311,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 2305 . A <*> 0 . DP=4;I16=2,2,0,0,140,5134,0,0,240,14400,0,0,63,1335,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2306 . A <*> 0 . DP=4;I16=2,2,0,0,140,5562,0,0,240,14400,0,0,65,1363,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 2307 . T <*> 0 . DP=4;I16=2,2,0,0,154,5972,0,0,240,14400,0,0,67,1395,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 2308 . C <*> 0 . DP=4;I16=2,2,0,0,159,6375,0,0,240,14400,0,0,69,1431,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 2309 . C <*> 0 . DP=4;I16=2,2,0,0,151,5835,0,0,240,14400,0,0,71,1471,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 2310 . C <*> 0 . DP=4;I16=2,2,0,0,151,5883,0,0,240,14400,0,0,73,1515,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2311 . A <*> 0 . DP=4;I16=2,2,0,0,149,5751,0,0,240,14400,0,0,75,1563,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 2312 . G <*> 0 . DP=4;I16=2,2,0,0,138,5634,0,0,240,14400,0,0,77,1615,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 2313 . C <*> 0 . DP=4;I16=2,2,0,0,141,5299,0,0,240,14400,0,0,79,1671,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 2314 . A C,<*> 0 . DP=4;I16=2,1,0,1,122,4964,6,36,180,10800,60,3600,66,1506,15,225;QS=0.953125,0.046875,0;SGB=-0.379885;RPBZ=-1.34164;MQBZ=0;MQSBZ=0;BQBZ=-1.41421;SCBZ=1.73205;MQ0F=0 PL 0,4,107,9,110,109 17 2315 . C <*> 0 . DP=5;I16=2,3,0,0,149,5511,0,0,300,18000,0,0,91,1859,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 2316 . T <*> 0 . DP=5;I16=2,3,0,0,193,7565,0,0,300,18000,0,0,94,1944,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 2317 . T <*> 0 . DP=5;I16=2,3,0,0,196,7722,0,0,300,18000,0,0,97,2035,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 2318 . T <*> 0 . DP=5;I16=2,3,0,0,189,7259,0,0,300,18000,0,0,100,2132,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 2319 . G <*> 0 . DP=5;I16=2,3,0,0,192,7438,0,0,300,18000,0,0,103,2235,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 2320 . G <*> 0 . DP=5;I16=2,3,0,0,180,6640,0,0,300,18000,0,0,106,2344,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 2321 . G <*> 0 . DP=5;I16=2,3,0,0,193,7589,0,0,300,18000,0,0,109,2459,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 2322 . A <*> 0 . DP=5;I16=2,3,0,0,205,8431,0,0,300,18000,0,0,112,2580,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 2323 . G <*> 0 . DP=5;I16=2,3,0,0,176,6236,0,0,300,18000,0,0,115,2707,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 2324 . G <*> 0 . DP=5;I16=2,3,0,0,184,6886,0,0,300,18000,0,0,117,2789,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 2325 . C <*> 0 . DP=5;I16=2,3,0,0,145,5195,0,0,300,18000,0,0,118,2824,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 2326 . C <*> 0 . DP=5;I16=2,3,0,0,156,5512,0,0,300,18000,0,0,119,2861,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 2327 . G <*> 0 . DP=5;I16=2,3,0,0,182,6706,0,0,300,18000,0,0,120,2900,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 2328 . A <*> 0 . DP=5;I16=2,3,0,0,196,7864,0,0,300,18000,0,0,121,2941,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 2329 . G <*> 0 . DP=5;I16=2,3,0,0,182,6898,0,0,300,18000,0,0,122,2984,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 2330 . C <*> 0 . DP=6;I16=2,4,0,0,218,8192,0,0,360,21600,0,0,123,3029,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 2331 . T <*> 0 . DP=6;I16=2,4,0,0,245,10069,0,0,360,21600,0,0,125,3077,0,0;QS=1,0;MQ0F=0 PL 0,18,200 17 2332 . A <*> 0 . DP=6;I16=2,4,0,0,249,10383,0,0,360,21600,0,0,127,3129,0,0;QS=1,0;MQ0F=0 PL 0,18,204 17 2333 . G <*> 0 . DP=7;I16=2,5,0,0,243,9097,0,0,420,25200,0,0,128,3134,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 2334 . G <*> 0 . DP=7;I16=2,5,0,0,262,9874,0,0,420,25200,0,0,130,3142,0,0;QS=1,0;MQ0F=0 PL 0,21,202 17 2335 . A <*> 0 . DP=7;I16=2,5,0,0,276,11088,0,0,420,25200,0,0,132,3154,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 2336 . G <*> 0 . DP=7;I16=2,5,0,0,267,10225,0,0,420,25200,0,0,134,3170,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 2337 . G <*> 0 . DP=7;I16=2,5,0,0,267,10239,0,0,420,25200,0,0,136,3190,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 2338 . A <*> 0 . DP=7;I16=2,5,0,0,249,9131,0,0,420,25200,0,0,138,3214,0,0;QS=1,0;MQ0F=0 PL 0,21,194 17 2339 . T <*> 0 . DP=7;I16=2,5,0,0,255,9565,0,0,420,25200,0,0,140,3242,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 2340 . C <*> 0 . DP=7;I16=2,5,0,0,223,7325,0,0,420,25200,0,0,142,3274,0,0;QS=1,0;MQ0F=0 PL 0,21,173 17 2341 . G <*> 0 . DP=7;I16=2,5,0,0,240,8346,0,0,420,25200,0,0,144,3310,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 2342 . T <*> 0 . DP=7;I16=2,5,0,0,277,11065,0,0,420,25200,0,0,146,3350,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 2343 . T <*> 0 . DP=7;I16=2,5,0,0,276,11018,0,0,420,25200,0,0,147,3345,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 2344 . T <*> 0 . DP=7;I16=2,5,0,0,261,9857,0,0,420,25200,0,0,148,3346,0,0;QS=1,0;MQ0F=0 PL 0,21,202 17 2345 . G <*> 0 . DP=7;I16=2,5,0,0,267,10239,0,0,420,25200,0,0,149,3353,0,0;QS=1,0;MQ0F=0 PL 0,21,206 17 2346 . A <*> 0 . DP=7;I16=2,5,0,0,285,11661,0,0,420,25200,0,0,150,3366,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 2347 . G <*> 0 . DP=7;I16=2,5,0,0,244,8718,0,0,420,25200,0,0,151,3385,0,0;QS=1,0;MQ0F=0 PL 0,21,190 17 2348 . T <*> 0 . DP=7;I16=2,5,0,0,231,8457,0,0,420,25200,0,0,152,3410,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 2349 . C <*> 0 . DP=7;I16=2,5,0,0,258,9658,0,0,420,25200,0,0,153,3441,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 2350 . C <*> 0 . DP=7;I16=2,5,0,0,255,9511,0,0,420,25200,0,0,154,3478,0,0;QS=1,0;MQ0F=0 PL 0,21,198 17 2351 . A <*> 0 . DP=7;I16=2,5,0,0,289,11991,0,0,420,25200,0,0,155,3521,0,0;QS=1,0;MQ0F=0 PL 0,21,222 17 2352 . G <*> 0 . DP=7;I16=2,5,0,0,271,10521,0,0,420,25200,0,0,155,3521,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 2353 . C <*> 0 . DP=7;I16=2,5,0,0,267,10253,0,0,420,25200,0,0,155,3529,0,0;QS=1,0;MQ0F=0 PL 0,21,205 17 2354 . A <*> 0 . DP=7;I16=2,5,0,0,277,11071,0,0,420,25200,0,0,155,3545,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 2355 . G <*> 0 . DP=7;I16=2,5,0,0,254,9266,0,0,420,25200,0,0,155,3569,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 2356 . T <*> 0 . DP=7;I16=2,5,0,0,285,11661,0,0,420,25200,0,0,154,3550,0,0;QS=1,0;MQ0F=0 PL 0,21,219 17 2357 . T <*> 0 . DP=7;I16=2,5,0,0,285,11651,0,0,420,25200,0,0,153,3537,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 2358 . T <*> 0 . DP=7;I16=2,5,0,0,284,11544,0,0,420,25200,0,0,152,3530,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 2359 . G <*> 0 . DP=7;I16=2,5,0,0,275,10815,0,0,420,25200,0,0,150,3478,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 2360 . A <*> 0 . DP=7;I16=2,5,0,0,286,11734,0,0,420,25200,0,0,148,3430,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 2361 . G <*> 0 . DP=7;I16=2,5,0,0,211,7113,0,0,420,25200,0,0,146,3386,0,0;QS=1,0;MQ0F=0 PL 0,21,168 17 2362 . A C,<*> 0 . DP=7;I16=2,4,0,1,189,6417,4,16,360,21600,60,3600,119,2721,25,625;QS=0.979275,0.0207254,0;SGB=-0.379885;RPBZ=0;MQBZ=0;MQSBZ=0;BQBZ=-1.5;SCBZ=-0.408248;MQ0F=0 PL 0,12,152,18,155,152 17 2363 . C <*> 0 . DP=7;I16=2,5,0,0,236,8478,0,0,420,25200,0,0,142,3310,0,0;QS=1,0;MQ0F=0 PL 0,21,187 17 2364 . C <*> 0 . DP=7;I16=2,5,0,0,263,9923,0,0,420,25200,0,0,140,3278,0,0;QS=1,0;MQ0F=0 PL 0,21,201 17 2365 . A <*> 0 . DP=7;I16=2,5,0,0,286,11700,0,0,420,25200,0,0,138,3250,0,0;QS=1,0;MQ0F=0 PL 0,21,221 17 2366 . G <*> 0 . DP=7;I16=2,5,0,0,267,10253,0,0,420,25200,0,0,136,3226,0,0;QS=1,0;MQ0F=0 PL 0,21,206 17 2367 . C <*> 0 . DP=7;I16=2,5,0,0,260,9728,0,0,420,25200,0,0,134,3206,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 2368 . C <*> 0 . DP=6;I16=1,5,0,0,239,9547,0,0,360,21600,0,0,133,3189,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 2369 . T <*> 0 . DP=6;I16=1,5,0,0,237,9409,0,0,360,21600,0,0,132,3174,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 2370 . G <*> 0 . DP=6;I16=1,5,0,0,236,9334,0,0,360,21600,0,0,131,3161,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 2371 . G <*> 0 . DP=6;I16=1,5,0,0,233,9111,0,0,360,21600,0,0,130,3150,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 2372 . C <*> 0 . DP=6;I16=1,5,0,0,216,7802,0,0,360,21600,0,0,129,3141,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 2373 . C <*> 0 . DP=6;I16=1,5,0,0,220,8088,0,0,360,21600,0,0,128,3134,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 2374 . A <*> 0 . DP=6;I16=1,5,0,0,232,9038,0,0,360,21600,0,0,126,3080,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 2375 . A <*> 0 . DP=6;I16=1,5,0,0,222,8246,0,0,360,21600,0,0,123,2981,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 2376 . T <*> 0 . DP=6;I16=1,5,0,0,210,7540,0,0,360,21600,0,0,120,2888,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 2377 . A <*> 0 . DP=5;I16=0,5,0,0,189,7193,0,0,300,18000,0,0,118,2800,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 2378 . C <*> 0 . DP=5;I16=0,5,0,0,155,4809,0,0,300,18000,0,0,116,2716,0,0;QS=1,0;MQ0F=0 PL 0,15,108 17 2379 . G <*> 0 . DP=5;I16=0,5,0,0,198,7862,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2380 . G <*> 0 . DP=5;I16=0,5,0,0,187,7071,0,0,300,18000,0,0,112,2560,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2381 . C <*> 0 . DP=5;I16=0,5,0,0,185,6943,0,0,300,18000,0,0,110,2488,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2382 . A <*> 0 . DP=5;I16=0,5,0,0,180,6734,0,0,300,18000,0,0,108,2420,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 2383 . A <*> 0 . DP=5;I16=0,5,0,0,197,7813,0,0,300,18000,0,0,105,2307,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2384 . A <*> 0 . DP=5;I16=0,5,0,0,185,6925,0,0,300,18000,0,0,102,2200,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 2385 . A <*> 0 . DP=5;I16=0,5,0,0,190,7234,0,0,300,18000,0,0,99,2099,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2386 . C <*> 0 . DP=5;I16=0,5,0,0,181,6715,0,0,300,18000,0,0,96,2004,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 2387 . C <*> 0 . DP=5;I16=0,5,0,0,182,6628,0,0,300,18000,0,0,93,1915,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 2388 . C <*> 0 . DP=5;I16=0,5,0,0,189,7169,0,0,300,18000,0,0,90,1832,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2389 . A <*> 0 . DP=5;I16=0,5,0,0,195,7765,0,0,300,18000,0,0,87,1755,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2390 . G <*> 0 . DP=5;I16=0,5,0,0,178,6372,0,0,300,18000,0,0,84,1684,0,0;QS=1,0;MQ0F=0 PL 0,15,126 17 2391 . T <*> 0 . DP=5;I16=0,5,0,0,196,7750,0,0,300,18000,0,0,81,1619,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2392 . C <*> 0 . DP=5;I16=0,5,0,0,181,6723,0,0,300,18000,0,0,78,1560,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 2393 . T <*> 0 . DP=5;I16=0,5,0,0,187,7067,0,0,300,18000,0,0,75,1507,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2394 . C <*> 0 . DP=5;I16=0,5,0,0,186,6976,0,0,300,18000,0,0,72,1460,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2395 . T <*> 0 . DP=5;I16=0,5,0,0,179,6497,0,0,300,18000,0,0,69,1419,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 2396 . A <*> 0 . DP=5;I16=0,5,0,0,184,6802,0,0,300,18000,0,0,66,1384,0,0;QS=1,0;MQ0F=0 PL 0,15,130 17 2397 . C <*> 0 . DP=5;I16=0,5,0,0,182,6652,0,0,300,18000,0,0,63,1355,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 2398 . A <*> 0 . DP=5;I16=0,5,0,0,186,6970,0,0,300,18000,0,0,60,1332,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2399 . A <*> 0 . DP=4;I16=0,4,0,0,151,5783,0,0,240,14400,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2400 . A <*> 0 . DP=3;I16=0,3,0,0,119,4723,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2401 . A <*> 0 . DP=3;I16=0,3,0,0,118,4642,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2402 . A <*> 0 . DP=3;I16=0,3,0,0,119,4721,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2403 . A <*> 0 . DP=3;I16=0,3,0,0,116,4490,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 2404 . T <*> 0 . DP=3;I16=0,3,0,0,104,3608,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,87 17 2405 . A <*> 0 . DP=3;I16=0,3,0,0,104,3658,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2406 . C <*> 0 . DP=3;I16=0,3,0,0,108,3896,0,0,180,10800,0,0,50,1202,0,0;QS=1,0;MQ0F=0 PL 0,9,90 17 2407 . A <*> 0 . DP=3;I16=0,3,0,0,106,3790,0,0,180,10800,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,9,89 17 2408 . A <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2409 . A <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,45,1017,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 2410 . A <*> 0 . DP=2;I16=0,2,0,0,80,3200,0,0,120,7200,0,0,43,929,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2411 . A <*> 0 . DP=2;I16=0,2,0,0,76,2906,0,0,120,7200,0,0,41,845,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2412 . A <*> 0 . DP=2;I16=0,2,0,0,76,2906,0,0,120,7200,0,0,39,765,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2413 . C <*> 0 . DP=2;I16=0,2,0,0,79,3121,0,0,120,7200,0,0,37,689,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 2414 . A <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,35,617,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2415 . A <*> 0 . DP=2;I16=0,2,0,0,70,2452,0,0,120,7200,0,0,33,549,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2416 . C <*> 0 . DP=2;I16=0,2,0,0,74,2756,0,0,120,7200,0,0,31,485,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 2417 . T <*> 0 . DP=3;I16=1,2,0,0,97,3249,0,0,149,8041,0,0,29,425,0,0;QS=1,0;MQ0F=0 PL 0,9,92 17 2418 . A <*> 0 . DP=3;I16=1,2,0,0,119,4741,0,0,149,8041,0,0,28,370,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 2419 . G <*> 0 . DP=4;I16=2,2,0,0,142,5114,0,0,209,11641,0,0,27,321,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2420 . C <*> 0 . DP=4;I16=2,2,0,0,146,5362,0,0,209,11641,0,0,27,279,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 2421 . C <*> 0 . DP=4;I16=2,2,0,0,139,4885,0,0,209,11641,0,0,27,245,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2422 . A <*> 0 . DP=4;I16=2,2,0,0,159,6335,0,0,209,11641,0,0,27,219,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 2423 . G <*> 0 . DP=4;I16=2,2,0,0,148,5486,0,0,209,11641,0,0,27,201,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2424 . G <*> 0 . DP=4;I16=2,2,0,0,137,4787,0,0,209,11641,0,0,27,191,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2425 . C <*> 0 . DP=4;I16=2,2,0,0,133,4541,0,0,209,11641,0,0,27,189,0,0;QS=1,0;MQ0F=0 PL 0,12,114 17 2426 . G <*> 0 . DP=4;I16=2,2,0,0,124,3894,0,0,209,11641,0,0,27,195,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2427 . T <*> 0 . DP=4;I16=2,2,0,0,115,3831,0,0,209,11641,0,0,27,209,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 2428 . G <*> 0 . DP=4;I16=2,2,0,0,145,5265,0,0,209,11641,0,0,27,231,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 2429 . G <*> 0 . DP=4;I16=2,2,0,0,135,4571,0,0,209,11641,0,0,27,261,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2430 . T <*> 0 . DP=4;I16=2,2,0,0,141,5005,0,0,209,11641,0,0,27,299,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2431 . G <*> 0 . DP=3;I16=2,1,0,0,114,4338,0,0,149,8041,0,0,28,344,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2432 . G <*> 0 . DP=3;I16=2,1,0,0,113,4261,0,0,149,8041,0,0,29,395,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 2433 . T <*> 0 . DP=3;I16=2,1,0,0,99,3365,0,0,149,8041,0,0,30,452,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 2434 . G <*> 0 . DP=2;I16=2,0,0,0,67,2285,0,0,89,4441,0,0,32,514,0,0;QS=1,0;MQ0F=0 PL 0,6,62 17 2435 . C <*> 0 . DP=2;I16=2,0,0,0,66,2196,0,0,89,4441,0,0,34,580,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 2436 . A <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,89,4441,0,0,36,650,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 2437 . C <*> 0 . DP=2;I16=2,0,0,0,74,2746,0,0,89,4441,0,0,38,724,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 2438 . A <*> 0 . DP=2;I16=2,0,0,0,77,2977,0,0,89,4441,0,0,40,802,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2439 . C <*> 0 . DP=2;I16=2,0,0,0,62,1954,0,0,89,4441,0,0,42,884,0,0;QS=1,0;MQ0F=0 PL 0,6,57 17 2440 . C <*> 0 . DP=2;I16=2,0,0,0,75,2853,0,0,89,4441,0,0,44,970,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2441 . T <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,89,4441,0,0,46,1060,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 2442 . G <*> 0 . DP=2;I16=2,0,0,0,79,3133,0,0,89,4441,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2443 . T <*> 0 . DP=2;I16=2,0,0,0,76,2896,0,0,89,4441,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2444 . A <*> 0 . DP=2;I16=2,0,0,0,80,3200,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2445 . G <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2446 . T <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2447 . C <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2448 . C <*> 0 . DP=2;I16=2,0,0,0,81,3285,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2449 . C <*> 0 . DP=2;I16=2,0,0,0,80,3208,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,62 17 2450 . A <*> 0 . DP=2;I16=2,0,0,0,82,3362,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2451 . G <*> 0 . DP=2;I16=2,0,0,0,82,3370,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 2452 . C <*> 0 . DP=2;I16=2,0,0,0,78,3060,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2453 . T <*> 0 . DP=2;I16=2,0,0,0,88,3872,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 2454 . A <*> 0 . DP=2;I16=2,0,0,0,75,2825,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2455 . C <*> 0 . DP=2;I16=2,0,0,0,75,2837,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2456 . T <*> 0 . DP=2;I16=2,0,0,0,79,3145,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 2457 . C <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2458 . A <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2459 . G <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2460 . G <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2461 . A <*> 0 . DP=2;I16=2,0,0,0,86,3698,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 2462 . G <*> 0 . DP=2;I16=2,0,0,0,84,3528,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2463 . G <*> 0 . DP=2;I16=2,0,0,0,85,3617,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 2464 . C <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 2465 . T <*> 0 . DP=2;I16=2,0,0,0,88,3874,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 2466 . G <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 2467 . A <*> 0 . DP=2;I16=2,0,0,0,83,3449,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 17 2468 . G <*> 0 . DP=2;I16=2,0,0,0,80,3200,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2469 . G <*> 0 . DP=2;I16=2,0,0,0,69,2381,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,58 17 2470 . G <*> 0 . DP=2;I16=2,0,0,0,68,2312,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,58 17 2471 . G <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2472 . G <*> 0 . DP=2;I16=2,0,0,0,59,2005,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 2473 . A <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 2474 . A <*> 0 . DP=3;I16=3,0,0,0,105,3717,0,0,149,8041,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 2475 . G <*> 0 . DP=3;I16=3,0,0,0,109,3965,0,0,149,8041,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 2476 . G <*> 0 . DP=3;I16=3,0,0,0,105,3677,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,82 17 2477 . A <*> 0 . DP=3;I16=3,0,0,0,116,4488,0,0,149,8041,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 2478 . C <*> 0 . DP=3;I16=3,0,0,0,108,3902,0,0,149,8041,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,87 17 2479 . T <*> 0 . DP=3;I16=3,0,0,0,127,5377,0,0,149,8041,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 2480 . G <*> 0 . DP=3;I16=3,0,0,0,109,3969,0,0,149,8041,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2481 . C <*> 0 . DP=3;I16=3,0,0,0,112,4182,0,0,149,8041,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2482 . T <*> 0 . DP=3;I16=3,0,0,0,126,5292,0,0,149,8041,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 2483 . T <*> 0 . DP=3;I16=3,0,0,0,111,4113,0,0,149,8041,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,89 17 2484 . G <*> 0 . DP=3;I16=3,0,0,0,110,4046,0,0,149,8041,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 2485 . A <*> 0 . DP=3;I16=3,0,0,0,121,4885,0,0,149,8041,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 2486 . G <*> 0 . DP=3;I16=3,0,0,0,116,4486,0,0,149,8041,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,90 17 2487 . C <*> 0 . DP=3;I16=3,0,0,0,116,4488,0,0,149,8041,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 2488 . C <*> 0 . DP=3;I16=3,0,0,0,119,4729,0,0,149,8041,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 2489 . C <*> 0 . DP=3;I16=3,0,0,0,116,4504,0,0,149,8041,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 2490 . A <*> 0 . DP=4;I16=3,1,0,0,155,6025,0,0,209,11641,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 2491 . G <*> 0 . DP=4;I16=3,1,0,0,145,5265,0,0,209,11641,0,0,68,1540,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 2492 . G <*> 0 . DP=4;I16=3,1,0,0,140,5006,0,0,209,11641,0,0,70,1578,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2493 . A <*> 0 . DP=4;I16=3,1,0,0,151,5729,0,0,209,11641,0,0,71,1571,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 2494 . G <*> 0 . DP=4;I16=3,1,0,0,140,4942,0,0,209,11641,0,0,72,1570,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 2495 . T <*> 0 . DP=4;I16=3,1,0,0,126,4266,0,0,209,11641,0,0,72,1526,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2496 . T <*> 0 . DP=4;I16=3,1,0,0,137,4977,0,0,209,11641,0,0,72,1490,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 2497 . T <*> 0 . DP=4;I16=3,1,0,0,157,6169,0,0,209,11641,0,0,72,1462,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 2498 . G <*> 0 . DP=4;I16=3,1,0,0,148,5512,0,0,209,11641,0,0,72,1442,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 2499 . A <*> 0 . DP=4;I16=3,1,0,0,162,6620,0,0,209,11641,0,0,72,1430,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 2500 . G <*> 0 . DP=4;I16=3,1,0,0,152,5802,0,0,209,11641,0,0,71,1375,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2501 . G <*> 0 . DP=4;I16=3,1,0,0,143,5181,0,0,209,11641,0,0,70,1326,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 2502 . C <*> 0 . DP=4;I16=3,1,0,0,142,5094,0,0,209,11641,0,0,69,1283,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2503 . T <*> 0 . DP=4;I16=3,1,0,0,168,7060,0,0,209,11641,0,0,68,1246,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2504 . G <*> 0 . DP=4;I16=3,1,0,0,152,5812,0,0,209,11641,0,0,67,1215,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2505 . C <*> 0 . DP=4;I16=3,1,0,0,157,6177,0,0,209,11641,0,0,66,1190,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 2506 . T <*> 0 . DP=5;I16=3,2,0,0,195,7783,0,0,269,15241,0,0,65,1171,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 2507 . G <*> 0 . DP=5;I16=3,2,0,0,174,6350,0,0,269,15241,0,0,65,1159,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 2508 . T <*> 0 . DP=5;I16=3,2,0,0,191,7331,0,0,269,15241,0,0,65,1155,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 2509 . G <*> 0 . DP=5;I16=3,2,0,0,192,7402,0,0,269,15241,0,0,65,1159,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 2510 . A <*> 0 . DP=5;I16=3,2,0,0,190,7330,0,0,269,15241,0,0,65,1171,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 2511 . G <*> 0 . DP=5;I16=3,2,0,0,186,6948,0,0,269,15241,0,0,65,1191,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 2512 . C <*> 0 . DP=5;I16=3,2,0,0,192,7376,0,0,269,15241,0,0,65,1219,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 2513 . T <*> 0 . DP=5;I16=3,2,0,0,185,6911,0,0,269,15241,0,0,65,1255,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 2514 . G <*> 0 . DP=5;I16=3,2,0,0,181,6599,0,0,269,15241,0,0,65,1299,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 2515 . T <*> 0 . DP=5;I16=3,2,0,0,170,5938,0,0,269,15241,0,0,65,1351,0,0;QS=1,0;MQ0F=0 PL 0,15,141 17 2516 . G <*> 0 . DP=5;I16=3,2,0,0,176,6216,0,0,269,15241,0,0,64,1360,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2517 . A <*> 0 . DP=5;I16=3,2,0,0,188,7110,0,0,269,15241,0,0,63,1375,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 2518 . T <*> 0 . DP=4;I16=2,2,0,0,160,6414,0,0,240,14400,0,0,63,1395,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 2519 . C <*> 0 . DP=4;I16=2,2,0,0,136,4734,0,0,240,14400,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2520 . G <*> 0 . DP=3;I16=1,2,0,0,107,3865,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 2521 . C <*> 0 . DP=3;I16=1,2,0,0,117,4563,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 2522 . A <*> 0 . DP=3;I16=1,2,0,0,121,4883,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 2523 . T <*> 0 . DP=3;I16=1,2,0,0,124,5134,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 2524 . C <*> 0 . DP=3;I16=1,2,0,0,119,4721,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 2525 . A <*> 0 . DP=3;I16=1,2,0,0,124,5126,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 2526 . C <*> 0 . DP=3;I16=1,2,0,0,119,4723,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 2527 . T <*> 0 . DP=3;I16=1,2,0,0,127,5381,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,119 17 2528 . G <*> 0 . DP=3;I16=1,2,0,0,127,5379,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,119 17 2529 . C <*> 0 . DP=3;I16=1,2,0,0,124,5134,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 2530 . A <*> 0 . DP=3;I16=1,2,0,0,123,5045,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,116 17 2531 . T <*> 0 . DP=3;I16=1,2,0,0,129,5553,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,122 17 2532 . T <*> 0 . DP=3;I16=1,2,0,0,124,5128,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 2533 . C <*> 0 . DP=3;I16=1,2,0,0,110,4036,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 2534 . C <*> 0 . DP=3;I16=1,2,0,0,116,4494,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 2535 . A <*> 0 . DP=3;I16=1,2,0,0,130,5642,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,123 17 2536 . G <*> 0 . DP=3;I16=1,2,0,0,125,5209,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,117 17 2537 . C <*> 0 . DP=3;I16=1,2,0,0,122,4962,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 2538 . C <*> 0 . DP=4;I16=2,2,0,0,137,4829,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2539 . C <*> 0 . DP=4;I16=2,2,0,0,125,3961,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 2540 . G <*> 0 . DP=4;I16=2,2,0,0,119,4027,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 2541 . G <*> 0 . DP=4;I16=2,2,0,0,153,5891,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 2542 . T A,<*> 0 . DP=4;I16=1,2,1,0,116,4534,7,49,180,10800,60,3600,75,1875,4,16;QS=0.943089,0.0569106,0;SGB=-0.379885;RPBZ=-1.34164;MQBZ=0;MQSBZ=0;BQBZ=-1.34164;SCBZ=0;MQ0F=0 PL 0,4,101,9,104,104 17 2543 . G <*> 0 . DP=4;I16=2,2,0,0,127,4511,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2544 . A <*> 0 . DP=4;I16=2,2,0,0,143,5367,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 2545 . C <*> 0 . DP=4;I16=2,2,0,0,142,5122,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 2546 . A <*> 0 . DP=4;I16=2,2,0,0,157,6259,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 2547 . G <*> 0 . DP=5;I16=3,2,0,0,169,6215,0,0,300,18000,0,0,84,1956,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2548 . A <*> 0 . DP=5;I16=3,2,0,0,195,7783,0,0,300,18000,0,0,86,1976,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 2549 . G <*> 0 . DP=5;I16=3,2,0,0,184,6862,0,0,300,18000,0,0,88,2000,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 2550 . T <*> 0 . DP=5;I16=3,2,0,0,167,5995,0,0,300,18000,0,0,89,1979,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 2551 . G <*> 0 . DP=5;I16=3,2,0,0,171,6245,0,0,300,18000,0,0,90,1964,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 2552 . A <*> 0 . DP=5;I16=3,2,0,0,192,7478,0,0,300,18000,0,0,91,1955,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 2553 . G <*> 0 . DP=5;I16=3,2,0,0,162,5456,0,0,300,18000,0,0,92,1952,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2554 . T <*> 0 . DP=5;I16=3,2,0,0,183,6813,0,0,300,18000,0,0,93,1955,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 2555 . C <*> 0 . DP=5;I16=3,2,0,0,184,6786,0,0,300,18000,0,0,94,1964,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 2556 . A <*> 0 . DP=5;I16=3,2,0,0,168,5758,0,0,300,18000,0,0,95,1979,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 2557 . C <*> 0 . DP=5;I16=3,2,0,0,172,6136,0,0,300,18000,0,0,96,2000,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 2558 . T <*> 0 . DP=5;I16=3,2,0,0,201,8083,0,0,300,18000,0,0,97,2027,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 2559 . G <*> 0 . DP=5;I16=3,2,0,0,179,6487,0,0,300,18000,0,0,98,2060,0,0;QS=1,0;MQ0F=0 PL 0,15,156 17 2560 . T <*> 0 . DP=5;I16=3,2,0,0,163,5739,0,0,300,18000,0,0,99,2099,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 2561 . C <*> 0 . DP=5;I16=3,2,0,0,175,6231,0,0,300,18000,0,0,100,2144,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 2562 . T <*> 0 . DP=5;I16=3,2,0,0,190,7478,0,0,300,18000,0,0,101,2195,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 2563 . C <*> 0 . DP=5;I16=3,2,0,0,163,5483,0,0,300,18000,0,0,102,2252,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2564 . A G,<*> 0 . DP=5;I16=0,0,3,2,0,0,137,4729,0,0,300,18000,0,0,102,2264;QS=0,1,0;VDB=0.709369;SGB=-0.590765;MQSBZ=0;MQ0F=0 PL 124,15,0,124,15,124 17 2565 . A <*> 0 . DP=5;I16=3,2,0,0,191,7347,0,0,300,18000,0,0,102,2280,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2566 . A <*> 0 . DP=5;I16=3,2,0,0,186,6998,0,0,300,18000,0,0,101,2251,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 2567 . A <*> 0 . DP=5;I16=3,2,0,0,191,7375,0,0,300,18000,0,0,100,2228,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2568 . A <*> 0 . DP=5;I16=3,2,0,0,192,7418,0,0,300,18000,0,0,99,2211,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 2569 . A <*> 0 . DP=5;I16=3,2,0,0,198,7886,0,0,300,18000,0,0,98,2200,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 2570 . G <*> 0 . DP=6;I16=4,2,0,0,215,7805,0,0,360,21600,0,0,97,2195,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 2571 . A <*> 0 . DP=6;I16=4,2,0,0,186,6058,0,0,360,21600,0,0,97,2197,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 2572 . A <*> 0 . DP=6;I16=4,2,0,0,210,7496,0,0,360,21600,0,0,97,2207,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 2573 . A <*> 0 . DP=6;I16=4,2,0,0,221,8385,0,0,360,21600,0,0,96,2174,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 2574 . G <*> 0 . DP=6;I16=4,2,0,0,216,7928,0,0,360,21600,0,0,95,2147,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2575 . G <*> 0 . DP=5;I16=3,2,0,0,157,5477,0,0,300,18000,0,0,95,2125,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2576 . A <*> 0 . DP=5;I16=3,2,0,0,150,5244,0,0,300,18000,0,0,95,2107,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2577 . A <*> 0 . DP=6;I16=4,2,0,0,184,6596,0,0,360,21600,0,0,95,2093,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 2578 . G <*> 0 . DP=6;I16=4,2,0,0,190,6578,0,0,360,21600,0,0,96,2084,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 2579 . A <*> 0 . DP=6;I16=4,2,0,0,213,7731,0,0,360,21600,0,0,97,2081,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 2580 . A <*> 0 . DP=6;I16=4,2,0,0,205,7169,0,0,360,21600,0,0,98,2084,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 2581 . A <*> 0 . DP=6;I16=4,2,0,0,199,6865,0,0,360,21600,0,0,99,2093,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 2582 . T <*> 0 . DP=6;I16=4,2,0,0,203,7043,0,0,360,21600,0,0,99,2059,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 2583 . A <*> 0 . DP=6;I16=4,2,0,0,218,7974,0,0,360,21600,0,0,99,2033,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2584 . A <*> 0 . DP=6;I16=4,2,0,0,227,8731,0,0,360,21600,0,0,99,2015,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 2585 . A <*> 0 . DP=6;I16=4,2,0,0,232,9042,0,0,360,21600,0,0,99,2005,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 2586 . G <*> 0 . DP=6;I16=4,2,0,0,213,7767,0,0,360,21600,0,0,99,2003,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 2587 . A C,<*> 0 . DP=6;I16=3,2,1,0,157,5641,6,36,300,18000,60,3600,74,1384,25,625;QS=0.96319,0.0368098,0;SGB=-0.379885;RPBZ=0.29277;MQBZ=0;MQSBZ=0;BQBZ=-1.46385;SCBZ=-0.447214;MQ0F=0 PL 0,9,133,15,136,134 17 2588 . A <*> 0 . DP=6;I16=4,2,0,0,197,6815,0,0,360,21600,0,0,99,2023,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 2589 . A <*> 0 . DP=6;I16=4,2,0,0,209,7591,0,0,360,21600,0,0,99,2045,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 2590 . A <*> 0 . DP=6;I16=4,2,0,0,193,6705,0,0,360,21600,0,0,99,2075,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 2591 . C <*> 0 . DP=5;I16=4,1,0,0,161,5591,0,0,300,18000,0,0,100,2112,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 2592 . A <*> 0 . DP=5;I16=4,1,0,0,166,5884,0,0,300,18000,0,0,101,2155,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 2593 . A <*> 0 . DP=5;I16=4,1,0,0,174,6594,0,0,300,18000,0,0,102,2204,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2594 . A <*> 0 . DP=5;I16=4,1,0,0,184,6994,0,0,300,18000,0,0,103,2259,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 2595 . T <*> 0 . DP=5;I16=4,1,0,0,172,6154,0,0,300,18000,0,0,104,2320,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 2596 . A <*> 0 . DP=5;I16=4,1,0,0,156,5464,0,0,300,18000,0,0,104,2336,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2597 . A <*> 0 . DP=5;I16=4,1,0,0,177,6327,0,0,300,18000,0,0,104,2356,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 2598 . A <*> 0 . DP=5;I16=4,1,0,0,194,7596,0,0,300,18000,0,0,104,2380,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 2599 . A <*> 0 . DP=5;I16=4,1,0,0,181,6739,0,0,300,18000,0,0,104,2408,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2600 . A <*> 0 . DP=5;I16=4,1,0,0,181,6727,0,0,300,18000,0,0,104,2440,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2601 . T <*> 0 . DP=5;I16=4,1,0,0,172,6068,0,0,300,18000,0,0,104,2476,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2602 . A <*> 0 . DP=6;I16=5,1,0,0,201,6887,0,0,360,21600,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 2603 . A <*> 0 . DP=6;I16=5,1,0,0,228,8730,0,0,360,21600,0,0,104,2510,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 2604 . T <*> 0 . DP=6;I16=5,1,0,0,199,6861,0,0,360,21600,0,0,104,2508,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 2605 . A <*> 0 . DP=6;I16=5,1,0,0,204,7606,0,0,360,21600,0,0,104,2510,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 2606 . G <*> 0 . DP=6;I16=5,1,0,0,180,6224,0,0,360,21600,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,18,144 17 2607 . T <*> 0 . DP=5;I16=5,0,0,0,187,7009,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 2608 . G <*> 0 . DP=5;I16=5,0,0,0,178,6390,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,127 17 2609 . C <*> 0 . DP=5;I16=5,0,0,0,171,6059,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 2610 . A <*> 0 . DP=5;I16=5,0,0,0,167,5737,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,121 17 2611 . G <*> 0 . DP=5;I16=5,0,0,0,164,5848,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 2612 . A <*> 0 . DP=5;I16=5,0,0,0,162,5884,0,0,300,18000,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,15,121 17 2613 . C <*> 0 . DP=5;I16=5,0,0,0,165,5651,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,120 17 2614 . A <*> 0 . DP=5;I16=5,0,0,0,197,7779,0,0,300,18000,0,0,111,2595,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2615 . A <*> 0 . DP=5;I16=5,0,0,0,200,8034,0,0,300,18000,0,0,111,2573,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2616 . A <*> 0 . DP=5;I16=5,0,0,0,201,8187,0,0,300,18000,0,0,111,2555,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 2617 . A <*> 0 . DP=5;I16=5,0,0,0,194,7650,0,0,300,18000,0,0,111,2541,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2618 . G <*> 0 . DP=5;I16=5,0,0,0,182,6774,0,0,300,18000,0,0,111,2531,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 2619 . G <*> 0 . DP=5;I16=5,0,0,0,174,6262,0,0,300,18000,0,0,111,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,127 17 2620 . C <*> 0 . DP=5;I16=5,0,0,0,155,5179,0,0,300,18000,0,0,111,2523,0,0;QS=1,0;MQ0F=0 PL 0,15,115 17 2621 . C <*> 0 . DP=5;I16=5,0,0,0,170,6010,0,0,300,18000,0,0,111,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 2622 . T <*> 0 . DP=5;I16=5,0,0,0,181,7187,0,0,300,18000,0,0,111,2531,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 2623 . T <*> 0 . DP=5;I16=5,0,0,0,177,6535,0,0,300,18000,0,0,110,2492,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 2624 . G <*> 0 . DP=5;I16=5,0,0,0,186,7004,0,0,300,18000,0,0,109,2459,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2625 . A <*> 0 . DP=5;I16=5,0,0,0,186,7126,0,0,300,18000,0,0,108,2432,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 2626 . C <*> 0 . DP=5;I16=5,0,0,0,169,5847,0,0,300,18000,0,0,107,2411,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 2627 . C <*> 0 . DP=5;I16=5,0,0,0,178,6516,0,0,300,18000,0,0,106,2396,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 2628 . C <*> 0 . DP=6;I16=6,0,0,0,181,6385,0,0,360,21600,0,0,104,2336,0,0;QS=1,0;MQ0F=0 PL 0,18,129 17 2629 . A <*> 0 . DP=6;I16=6,0,0,0,224,8478,0,0,360,21600,0,0,103,2281,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 2630 . T <*> 0 . DP=6;I16=6,0,0,0,208,7570,0,0,360,21600,0,0,102,2232,0,0;QS=1,0;MQ0F=0 PL 0,18,140 17 2631 . C <*> 0 . DP=6;I16=6,0,0,0,212,7674,0,0,360,21600,0,0,101,2189,0,0;QS=1,0;MQ0F=0 PL 0,18,142 17 2632 . T <*> 0 . DP=6;I16=6,0,0,0,249,10377,0,0,360,21600,0,0,100,2152,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 2633 . A <*> 0 . DP=6;I16=6,0,0,0,223,8405,0,0,360,21600,0,0,99,2121,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 2634 . G <*> 0 . DP=6;I16=6,0,0,0,225,8531,0,0,360,21600,0,0,98,2096,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 2635 . C <*> 0 . DP=6;I16=6,0,0,0,220,8358,0,0,360,21600,0,0,97,2077,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 2636 . T <*> 0 . DP=6;I16=6,0,0,0,242,9866,0,0,360,21600,0,0,96,2064,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 2637 . T <*> 0 . DP=6;I16=6,0,0,0,215,7859,0,0,360,21600,0,0,95,2057,0,0;QS=1,0;MQ0F=0 PL 0,18,144 17 2638 . T <*> 0 . DP=6;I16=6,0,0,0,198,6900,0,0,360,21600,0,0,94,2056,0,0;QS=1,0;MQ0F=0 PL 0,18,135 17 2639 . G <*> 0 . DP=5;I16=5,0,0,0,172,6166,0,0,300,18000,0,0,94,2060,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 2640 . G <*> 0 . DP=5;I16=5,0,0,0,156,5470,0,0,300,18000,0,0,94,2068,0,0;QS=1,0;MQ0F=0 PL 0,15,117 17 2641 . C <*> 0 . DP=5;I16=5,0,0,0,177,6535,0,0,300,18000,0,0,94,2080,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 2642 . C <*> 0 . DP=5;I16=5,0,0,0,180,6718,0,0,300,18000,0,0,94,2096,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 2643 . C <*> 0 . DP=5;I16=5,0,0,0,183,6947,0,0,300,18000,0,0,94,2116,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 2644 . T <*> 0 . DP=5;I16=5,0,0,0,200,8066,0,0,300,18000,0,0,94,2140,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 2645 . C <*> 0 . DP=5;I16=5,0,0,0,169,6431,0,0,300,18000,0,0,94,2168,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 2646 . A <*> 0 . DP=5;I16=5,0,0,0,177,6489,0,0,300,18000,0,0,93,2151,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 2647 . G <*> 0 . DP=5;I16=5,0,0,0,177,6539,0,0,300,18000,0,0,92,2140,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 2648 . C <*> 0 . DP=4;I16=4,0,0,0,154,5940,0,0,240,14400,0,0,92,2134,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 2649 . A <*> 0 . DP=4;I16=4,0,0,0,131,4745,0,0,240,14400,0,0,92,2132,0,0;QS=1,0;MQ0F=0 PL 0,12,105 17 2650 . T <*> 0 . DP=4;I16=4,0,0,0,153,5867,0,0,240,14400,0,0,92,2134,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 2651 . C <*> 0 . DP=4;I16=4,0,0,0,157,6201,0,0,240,14400,0,0,92,2140,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 2652 . A <*> 0 . DP=4;I16=4,0,0,0,154,5996,0,0,240,14400,0,0,92,2150,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 2653 . A <*> 0 . DP=4;I16=4,0,0,0,133,5725,0,0,240,14400,0,0,91,2115,0,0;QS=1,0;MQ0F=0 PL 0,12,109 17 2654 . C <*> 0 . DP=3;I16=3,0,0,0,118,4652,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2655 . C <*> 0 . DP=3;I16=3,0,0,0,114,4334,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 2656 . G <*> 0 . DP=3;I16=3,0,0,0,89,2653,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,74 17 2657 . C <*> 0 . DP=3;I16=3,0,0,0,118,4650,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2658 . T <*> 0 . DP=3;I16=3,0,0,0,128,5466,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 2659 . A <*> 0 . DP=3;I16=3,0,0,0,111,4139,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 2660 . G <*> 0 . DP=3;I16=3,0,0,0,112,4222,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 2661 . A <*> 0 . DP=3;I16=3,0,0,0,124,5130,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 2662 . T <*> 0 . DP=3;I16=3,0,0,0,118,4658,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2663 . A <*> 0 . DP=3;I16=3,0,0,0,121,4885,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 2664 . C <*> 0 . DP=3;I16=3,0,0,0,109,3969,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 2665 . G <*> 0 . DP=3;I16=3,0,0,0,93,2891,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 2666 . T <*> 0 . DP=3;I16=3,0,0,0,112,4210,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 2667 . C <*> 0 . DP=3;I16=3,0,0,0,117,4587,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2668 . C <*> 0 . DP=3;I16=3,0,0,0,113,4269,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 2669 . C <*> 0 . DP=3;I16=3,0,0,0,105,3681,0,0,180,10800,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 2670 . T <*> 0 . DP=3;I16=3,0,0,0,124,5126,0,0,180,10800,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 2671 . C <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2672 . C <*> 0 . DP=2;I16=2,0,0,0,82,3370,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2673 . C <*> 0 . DP=2;I16=2,0,0,0,82,3370,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2674 . T <*> 0 . DP=2;I16=2,0,0,0,87,3785,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,79 17 2675 . T <*> 0 . DP=2;I16=2,0,0,0,81,3285,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 17 2676 . T <*> 0 . DP=2;I16=2,0,0,0,82,3364,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2677 . C <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,77 17 2678 . T <*> 0 . DP=2;I16=2,0,0,0,88,3872,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,80 17 2679 . T <*> 0 . DP=2;I16=2,0,0,0,82,3364,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2680 . C <*> 0 . DP=2;I16=2,0,0,0,76,2896,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2681 . T <*> 0 . DP=2;I16=2,0,0,0,82,3380,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,75 17 2682 . G <*> 0 . DP=2;I16=2,0,0,0,70,2458,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2683 . G <*> 0 . DP=2;I16=2,0,0,0,58,1682,0,0,120,7200,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,6,53 17 2684 . G <*> 0 . DP=2;I16=2,0,0,0,68,2314,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,62 17 2685 . G <*> 0 . DP=2;I16=2,0,0,0,48,1352,0,0,120,7200,0,0,42,914,0,0;QS=1,0;MQ0F=0 PL 0,6,45 17 2686 . C <*> 0 . DP=2;I16=2,0,0,0,74,2740,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,68 17 2687 . A <*> 0 . DP=2;I16=2,0,0,0,65,2257,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 2688 . C <*> 0 . DP=2;I16=2,0,0,0,72,2600,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2689 . A <*> 0 . DP=2;I16=2,0,0,0,80,3208,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2690 . G <*> 0 . DP=2;I16=2,0,0,0,67,2249,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 2691 . G <*> 0 . DP=2;I16=2,0,0,0,69,2381,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 2692 . T <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 2693 . C <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2694 . A <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 2695 . C <*> 0 . DP=2;I16=2,0,0,0,68,2344,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 2696 . A <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 2697 . C <*> 0 . DP=2;I16=2,0,0,0,72,2594,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQ0F=0 PL 0,6,66 17 2698 . T <*> 0 . DP=3;I16=2,1,0,0,86,3532,0,0,149,8041,0,0,52,1170,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 2699 . C <*> 0 . DP=3;I16=2,1,0,0,107,3837,0,0,149,8041,0,0,52,1210,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2700 . T <*> 0 . DP=3;I16=2,1,0,0,123,5049,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 2701 . C <*> 0 . DP=3;I16=2,1,0,0,100,3394,0,0,149,8041,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 2702 . T <*> 0 . DP=3;I16=2,1,0,0,98,3482,0,0,149,8041,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,92 17 2703 . T <*> 0 . DP=2;I16=1,1,0,0,41,1105,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,41 17 2704 . C <*> 0 . DP=2;I16=1,1,0,0,55,1777,0,0,89,4441,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,55 17 2705 . C <*> 0 . DP=2;I16=1,1,0,0,56,1666,0,0,89,4441,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 2706 . A <*> 0 . DP=2;I16=1,1,0,0,82,3362,0,0,89,4441,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 2707 . G <*> 0 . DP=2;I16=1,1,0,0,60,1802,0,0,89,4441,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,60 17 2708 . G <*> 0 . DP=2;I16=1,1,0,0,57,1665,0,0,89,4441,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,57 17 2709 . T <*> 0 . DP=2;I16=1,1,0,0,48,1602,0,0,89,4441,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,6,48 17 2710 . C <*> 0 . DP=2;I16=1,1,0,0,47,1525,0,0,89,4441,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,47 17 2711 . T <*> 0 . DP=2;I16=1,1,0,0,78,3074,0,0,89,4441,0,0,42,914,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 2712 . A <*> 0 . DP=2;I16=1,1,0,0,66,2196,0,0,89,4441,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,65 17 2713 . G T,<*> 0 . DP=2;I16=1,0,0,1,37,1369,14,196,60,3600,29,841,15,225,25,625;QS=0.72549,0.27451,0;SGB=-0.379885;RPBZ=-1;MQBZ=-1;MQSBZ=-1;BQBZ=-1;SCBZ=1;MQ0F=0 PL 8,0,31,11,34,42 17 2714 . G <*> 0 . DP=2;I16=1,1,0,0,65,2125,0,0,89,4441,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2715 . A <*> 0 . DP=2;I16=1,1,0,0,63,2069,0,0,89,4441,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,63 17 2716 . T <*> 0 . DP=3;I16=1,2,0,0,95,3097,0,0,149,8041,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,9,90 17 2717 . G T,<*> 0 . DP=3;I16=1,1,0,1,72,2592,9,81,120,7200,29,841,12,122,25,625;QS=0.888889,0.111111,0;SGB=-0.379885;RPBZ=0;MQBZ=-1.41421;MQSBZ=-0.707107;BQBZ=-1.41421;SCBZ=1.22474;MQ0F=0 PL 1,0,63,7,66,68 17 2718 . C <*> 0 . DP=3;I16=1,2,0,0,74,2234,0,0,149,8041,0,0,37,729,0,0;QS=1,0;MQ0F=0 PL 0,9,71 17 2719 . A <*> 0 . DP=3;I16=1,2,0,0,115,4427,0,0,149,8041,0,0,37,715,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2720 . G <*> 0 . DP=3;I16=1,2,0,0,108,3902,0,0,149,8041,0,0,37,705,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 2721 . C <*> 0 . DP=3;I16=1,2,0,0,84,2952,0,0,149,8041,0,0,37,699,0,0;QS=1,0;MQ0F=0 PL 0,9,81 17 2722 . T <*> 0 . DP=3;I16=1,2,0,0,112,4194,0,0,149,8041,0,0,37,697,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2723 . G <*> 0 . DP=3;I16=1,2,0,0,80,2254,0,0,149,8041,0,0,37,699,0,0;QS=1,0;MQ0F=0 PL 0,9,76 17 2724 . A <*> 0 . DP=3;I16=1,2,0,0,91,2877,0,0,149,8041,0,0,37,705,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 2725 . G <*> 0 . DP=3;I16=1,2,0,0,74,2356,0,0,149,8041,0,0,37,715,0,0;QS=1,0;MQ0F=0 PL 0,9,72 17 2726 . G <*> 0 . DP=3;I16=1,2,0,0,52,1286,0,0,149,8041,0,0,37,729,0,0;QS=1,0;MQ0F=0 PL 0,9,49 17 2727 . G <*> 0 . DP=2;I16=0,2,0,0,65,2113,0,0,89,4441,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,56 17 2728 . G <*> 0 . DP=2;I16=0,2,0,0,53,1549,0,0,89,4441,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,50 17 2729 . T <*> 0 . DP=2;I16=0,2,0,0,75,2813,0,0,89,4441,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,62 17 2730 . G <*> 0 . DP=2;I16=0,2,0,0,52,1640,0,0,89,4441,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,49 17 2731 . C <*> 0 . DP=2;I16=0,2,0,0,57,1637,0,0,89,4441,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,52 17 2732 . C <*> 0 . DP=2;I16=0,2,0,0,41,881,0,0,89,4441,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,38 17 2733 . C A,<*> 0 . DP=2;I16=0,1,0,1,24,576,13,169,60,3600,29,841,17,289,25,625;QS=0.648649,0.351351,0;SGB=-0.379885;RPBZ=1;MQBZ=-1;BQBZ=-1;SCBZ=1;MQ0F=0 PL 7,0,18,10,21,28 17 2734 . C <*> 0 . DP=2;I16=0,2,0,0,46,1570,0,0,89,4441,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,44 17 2735 . T <*> 0 . DP=2;I16=0,2,0,0,48,1730,0,0,89,4441,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,6,46 17 2736 . C <*> 0 . DP=2;I16=0,2,0,0,40,1138,0,0,89,4441,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,38 17 2737 . T <*> 0 . DP=2;I16=0,2,0,0,69,2441,0,0,89,4441,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,64 17 2738 . T <*> 0 . DP=2;I16=0,2,0,0,50,1492,0,0,89,4441,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,47 17 2739 . A <*> 0 . DP=3;I16=1,2,0,0,82,2402,0,0,149,8041,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 2740 . C <*> 0 . DP=3;I16=1,2,0,0,76,2546,0,0,149,8041,0,0,50,1202,0,0;QS=1,0;MQ0F=0 PL 0,9,74 17 2741 . C <*> 0 . DP=3;I16=1,2,0,0,87,2961,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 2742 . A <*> 0 . DP=3;I16=1,2,0,0,96,3288,0,0,149,8041,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,92 17 2743 . T <*> 0 . DP=3;I16=1,2,0,0,104,3672,0,0,149,8041,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2744 . C <*> 0 . DP=3;I16=1,2,0,0,85,2969,0,0,149,8041,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,82 17 2745 . T <*> 0 . DP=3;I16=1,2,0,0,109,4125,0,0,149,8041,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 2746 . A <*> 0 . DP=3;I16=1,2,0,0,89,3163,0,0,149,8041,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,86 17 2747 . A <*> 0 . DP=3;I16=1,2,0,0,100,3686,0,0,149,8041,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 2748 . T <*> 0 . DP=3;I16=1,2,0,0,119,4723,0,0,149,8041,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 2749 . C <*> 0 . DP=3;I16=1,2,0,0,107,3837,0,0,149,8041,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2750 . T <*> 0 . DP=4;I16=2,2,0,0,141,5111,0,0,209,11641,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 2751 . G <*> 0 . DP=4;I16=2,2,0,0,115,4029,0,0,209,11641,0,0,62,1346,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 2752 . T <*> 0 . DP=4;I16=2,2,0,0,130,4356,0,0,209,11641,0,0,63,1327,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 2753 . G <*> 0 . DP=4;I16=2,2,0,0,126,4374,0,0,209,11641,0,0,64,1314,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 2754 . C <*> 0 . DP=4;I16=2,2,0,0,120,4208,0,0,209,11641,0,0,65,1307,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 2755 . C G,<*> 0 . DP=4;I16=2,1,0,1,103,3709,7,49,180,10800,29,841,46,906,20,400;QS=0.936364,0.0636364,0;SGB=-0.379885;RPBZ=1.34164;MQBZ=-1.73205;MQSBZ=-1;BQBZ=-1.34164;SCBZ=1.73205;MQ0F=0 PL 0,4,89,9,92,91 17 2756 . C <*> 0 . DP=4;I16=2,2,0,0,109,3745,0,0,209,11641,0,0,67,1311,0,0;QS=1,0;MQ0F=0 PL 0,12,100 17 2757 . T <*> 0 . DP=5;I16=3,2,0,0,168,6208,0,0,269,15241,0,0,68,1322,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2758 . T <*> 0 . DP=5;I16=3,2,0,0,160,5916,0,0,269,15241,0,0,70,1340,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2759 . A <*> 0 . DP=5;I16=3,2,0,0,170,5970,0,0,269,15241,0,0,72,1366,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2760 . T <*> 0 . DP=5;I16=3,2,0,0,172,6448,0,0,269,15241,0,0,74,1400,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2761 . T <*> 0 . DP=5;I16=3,2,0,0,170,6570,0,0,269,15241,0,0,76,1442,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 2762 . T <*> 0 . DP=6;I16=3,3,0,0,210,7698,0,0,329,18841,0,0,78,1492,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 2763 . C A,<*> 0 . DP=6;I16=3,2,0,1,182,6872,13,169,300,18000,29,841,69,1407,12,144;QS=0.933333,0.0666667,0;SGB=-0.379885;RPBZ=1.46385;MQBZ=-2.23607;MQSBZ=-1;BQBZ=-1.46385;SCBZ=1.73205;MQ0F=0 PL 0,5,147,15,150,153 17 2764 . C <*> 0 . DP=6;I16=3,3,0,0,192,7040,0,0,329,18841,0,0,84,1620,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 2765 . T <*> 0 . DP=6;I16=3,3,0,0,223,8627,0,0,329,18841,0,0,86,1648,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 2766 . C <*> 0 . DP=7;I16=3,4,0,0,226,8350,0,0,389,22441,0,0,88,1684,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 2767 . T <*> 0 . DP=7;I16=3,4,0,0,270,10618,0,0,389,22441,0,0,91,1729,0,0;QS=1,0;MQ0F=0 PL 0,21,217 17 2768 . G <*> 0 . DP=7;I16=3,4,0,0,242,9326,0,0,389,22441,0,0,94,1784,0,0;QS=1,0;MQ0F=0 PL 0,21,198 17 2769 . C <*> 0 . DP=7;I16=3,4,0,0,247,9349,0,0,389,22441,0,0,97,1849,0,0;QS=1,0;MQ0F=0 PL 0,21,202 17 2770 . T <*> 0 . DP=7;I16=3,4,0,0,244,9040,0,0,389,22441,0,0,100,1924,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 2771 . T <*> 0 . DP=7;I16=3,4,0,0,253,9875,0,0,389,22441,0,0,103,2009,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 2772 . T <*> 0 . DP=7;I16=3,4,0,0,263,10013,0,0,389,22441,0,0,106,2104,0,0;QS=1,0;MQ0F=0 PL 0,21,210 17 2773 . A <*> 0 . DP=7;I16=3,4,0,0,258,9904,0,0,389,22441,0,0,109,2209,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 2774 . G <*> 0 . DP=7;I16=3,4,0,0,256,9640,0,0,389,22441,0,0,112,2324,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 2775 . T <*> 0 . DP=7;I16=3,4,0,0,250,9404,0,0,389,22441,0,0,115,2449,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 2776 . G <*> 0 . DP=7;I16=4,3,0,0,262,9920,0,0,420,25200,0,0,118,2532,0,0;QS=1,0;MQ0F=0 PL 0,21,210 17 2777 . A <*> 0 . DP=7;I16=4,3,0,0,274,10954,0,0,420,25200,0,0,122,2622,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 2778 . G <*> 0 . DP=7;I16=4,3,0,0,280,11260,0,0,420,25200,0,0,126,2720,0,0;QS=1,0;MQ0F=0 PL 0,21,224 17 2779 . G <*> 0 . DP=7;I16=4,3,0,0,272,10726,0,0,420,25200,0,0,130,2826,0,0;QS=1,0;MQ0F=0 PL 0,21,219 17 2780 . A <*> 0 . DP=7;I16=4,3,0,0,267,10351,0,0,420,25200,0,0,134,2940,0,0;QS=1,0;MQ0F=0 PL 0,21,215 17 2781 . A <*> 0 . DP=7;I16=4,3,0,0,293,12297,0,0,420,25200,0,0,138,3062,0,0;QS=1,0;MQ0F=0 PL 0,21,233 17 2782 . G <*> 0 . DP=7;I16=4,3,0,0,270,10624,0,0,420,25200,0,0,142,3192,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 2783 . A <*> 0 . DP=7;I16=4,3,0,0,288,11892,0,0,420,25200,0,0,145,3279,0,0;QS=1,0;MQ0F=0 PL 0,21,230 17 2784 . G <*> 0 . DP=7;I16=4,3,0,0,262,10226,0,0,420,25200,0,0,148,3372,0,0;QS=1,0;MQ0F=0 PL 0,21,212 17 2785 . G <*> 0 . DP=7;I16=4,3,0,0,254,9338,0,0,420,25200,0,0,151,3471,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 2786 . C <*> 0 . DP=7;I16=4,3,0,0,247,8929,0,0,420,25200,0,0,154,3576,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 2787 . C <*> 0 . DP=7;I16=4,3,0,0,248,9258,0,0,420,25200,0,0,157,3687,0,0;QS=1,0;MQ0F=0 PL 0,21,200 17 2788 . C <*> 0 . DP=7;I16=4,3,0,0,261,10047,0,0,420,25200,0,0,159,3753,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 2789 . C <*> 0 . DP=7;I16=4,3,0,0,281,11407,0,0,420,25200,0,0,161,3823,0,0;QS=1,0;MQ0F=0 PL 0,21,226 17 2790 . T <*> 0 . DP=7;I16=4,3,0,0,284,11656,0,0,420,25200,0,0,163,3897,0,0;QS=1,0;MQ0F=0 PL 0,21,227 17 2791 . G <*> 0 . DP=7;I16=4,3,0,0,281,11305,0,0,420,25200,0,0,165,3975,0,0;QS=1,0;MQ0F=0 PL 0,21,226 17 2792 . G <*> 0 . DP=7;I16=4,3,0,0,275,10919,0,0,420,25200,0,0,165,3957,0,0;QS=1,0;MQ0F=0 PL 0,21,221 17 2793 . T <*> 0 . DP=7;I16=4,3,0,0,268,10326,0,0,420,25200,0,0,165,3943,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 2794 . C <*> 0 . DP=7;I16=4,3,0,0,251,9369,0,0,420,25200,0,0,165,3933,0,0;QS=1,0;MQ0F=0 PL 0,21,201 17 2795 . C <*> 0 . DP=7;I16=4,3,0,0,276,10948,0,0,420,25200,0,0,165,3927,0,0;QS=1,0;MQ0F=0 PL 0,21,222 17 2796 . A <*> 0 . DP=7;I16=4,3,0,0,263,10027,0,0,420,25200,0,0,165,3925,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 2797 . T <*> 0 . DP=7;I16=4,3,0,0,267,10287,0,0,420,25200,0,0,165,3927,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 2798 . G <*> 0 . DP=7;I16=4,3,0,0,257,9639,0,0,420,25200,0,0,165,3933,0,0;QS=1,0;MQ0F=0 PL 0,21,205 17 2799 . A <*> 0 . DP=7;I16=4,3,0,0,271,10671,0,0,420,25200,0,0,165,3943,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 2800 . A <*> 0 . DP=7;I16=4,3,0,0,295,12483,0,0,420,25200,0,0,165,3957,0,0;QS=1,0;MQ0F=0 PL 0,21,237 17 2801 . G <*> 0 . DP=7;I16=4,3,0,0,267,10359,0,0,420,25200,0,0,165,3975,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 2802 . G <*> 0 . DP=7;I16=4,3,0,0,268,10456,0,0,420,25200,0,0,164,3946,0,0;QS=1,0;MQ0F=0 PL 0,21,215 17 2803 . G <*> 0 . DP=7;I16=4,3,0,0,258,9786,0,0,420,25200,0,0,163,3919,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 2804 . G <*> 0 . DP=7;I16=4,3,0,0,261,9987,0,0,420,25200,0,0,162,3894,0,0;QS=1,0;MQ0F=0 PL 0,21,210 17 2805 . C <*> 0 . DP=7;I16=4,3,0,0,257,9817,0,0,420,25200,0,0,161,3871,0,0;QS=1,0;MQ0F=0 PL 0,21,205 17 2806 . C <*> 0 . DP=7;I16=4,3,0,0,237,9207,0,0,420,25200,0,0,160,3850,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 2807 . T <*> 0 . DP=7;I16=4,3,0,0,282,11502,0,0,420,25200,0,0,159,3831,0,0;QS=1,0;MQ0F=0 PL 0,21,226 17 2808 . T <*> 0 . DP=7;I16=4,3,0,0,281,11323,0,0,420,25200,0,0,158,3814,0,0;QS=1,0;MQ0F=0 PL 0,21,225 17 2809 . T <*> 0 . DP=7;I16=4,3,0,0,282,11432,0,0,420,25200,0,0,157,3799,0,0;QS=1,0;MQ0F=0 PL 0,21,226 17 2810 . C <*> 0 . DP=7;I16=4,3,0,0,268,10534,0,0,420,25200,0,0,156,3786,0,0;QS=1,0;MQ0F=0 PL 0,21,215 17 2811 . A <*> 0 . DP=7;I16=4,3,0,0,286,11696,0,0,420,25200,0,0,155,3775,0,0;QS=1,0;MQ0F=0 PL 0,21,228 17 2812 . G <*> 0 . DP=7;I16=4,3,0,0,270,10622,0,0,420,25200,0,0,154,3766,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 2813 . A <*> 0 . DP=7;I16=4,3,0,0,270,10708,0,0,420,25200,0,0,153,3759,0,0;QS=1,0;MQ0F=0 PL 0,21,217 17 2814 . G <*> 0 . DP=7;I16=4,3,0,0,253,9497,0,0,420,25200,0,0,152,3754,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 2815 . A <*> 0 . DP=7;I16=4,3,0,0,258,10102,0,0,420,25200,0,0,150,3702,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 2816 . C <*> 0 . DP=7;I16=4,3,0,0,225,8035,0,0,420,25200,0,0,148,3654,0,0;QS=1,0;MQ0F=0 PL 0,21,180 17 2817 . G <*> 0 . DP=7;I16=4,3,0,0,226,7314,0,0,420,25200,0,0,147,3609,0,0;QS=1,0;MQ0F=0 PL 0,21,180 17 2818 . G <*> 0 . DP=7;I16=4,3,0,0,258,9646,0,0,420,25200,0,0,147,3567,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 2819 . G <*> 0 . DP=7;I16=4,3,0,0,243,8655,0,0,420,25200,0,0,147,3529,0,0;QS=1,0;MQ0F=0 PL 0,21,196 17 2820 . G <*> 0 . DP=7;I16=4,3,0,0,234,8150,0,0,420,25200,0,0,147,3495,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 2821 . A G,<*> 0 . DP=8;I16=4,3,0,1,210,6834,2,4,420,25200,60,3600,147,3465,25,625;QS=0.981308,0.0186916,0;SGB=-0.379885;RPBZ=-1.5367;MQBZ=0;MQSBZ=0;BQBZ=-1.54604;SCBZ=1.75;MQ0F=0 PL 0,15,164,21,167,164 17 2822 . C <*> 0 . DP=8;I16=4,4,0,0,216,6518,0,0,480,28800,0,0,172,4064,0,0;QS=1,0;MQ0F=0 PL 0,24,172 17 2823 . C <*> 0 . DP=8;I16=4,4,0,0,251,8419,0,0,480,28800,0,0,172,4042,0,0;QS=1,0;MQ0F=0 PL 0,24,197 17 2824 . C <*> 0 . DP=8;I16=4,4,0,0,276,10170,0,0,480,28800,0,0,172,4024,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 2825 . C <*> 0 . DP=8;I16=4,4,0,0,267,9391,0,0,480,28800,0,0,172,4010,0,0;QS=1,0;MQ0F=0 PL 0,24,208 17 2826 . T <*> 0 . DP=8;I16=4,4,0,0,286,10300,0,0,480,28800,0,0,171,3951,0,0;QS=1,0;MQ0F=0 PL 0,24,220 17 2827 . G <*> 0 . DP=8;I16=4,4,0,0,273,9663,0,0,480,28800,0,0,170,3898,0,0;QS=1,0;MQ0F=0 PL 0,24,214 17 2828 . A <*> 0 . DP=9;I16=4,5,0,0,282,10174,0,0,540,32400,0,0,169,3851,0,0;QS=1,0;MQ0F=0 PL 0,27,218 17 2829 . G <*> 0 . DP=9;I16=4,5,0,0,306,10532,0,0,540,32400,0,0,169,3811,0,0;QS=1,0;MQ0F=0 PL 0,27,226 17 2830 . G <*> 0 . DP=9;I16=4,5,0,0,293,10083,0,0,540,32400,0,0,169,3779,0,0;QS=1,0;MQ0F=0 PL 0,27,222 17 2831 . A <*> 0 . DP=10;I16=5,5,0,0,353,12747,0,0,600,36000,0,0,169,3755,0,0;QS=1,0;MQ0F=0 PL 0,30,254 17 2832 . G <*> 0 . DP=10;I16=5,5,0,0,307,10313,0,0,600,36000,0,0,170,3740,0,0;QS=1,0;MQ0F=0 PL 0,30,224 17 2833 . C <*> 0 . DP=10;I16=5,5,0,0,363,13247,0,0,600,36000,0,0,170,3686,0,0;QS=1,0;MQ0F=0 PL 0,30,255 17 2834 . C <*> 0 . DP=10;I16=5,5,0,0,340,11906,0,0,600,36000,0,0,170,3644,0,0;QS=1,0;MQ0F=0 PL 0,30,243 17 2835 . C <*> 0 . DP=10;I16=5,5,0,0,319,11431,0,0,600,36000,0,0,170,3614,0,0;QS=1,0;MQ0F=0 PL 0,30,234 17 2836 . C <*> 0 . DP=10;I16=5,5,0,0,272,8490,0,0,600,36000,0,0,170,3596,0,0;QS=1,0;MQ0F=0 PL 0,30,198 17 2837 . G <*> 0 . DP=10;I16=5,5,0,0,255,7771,0,0,600,36000,0,0,170,3590,0,0;QS=1,0;MQ0F=0 PL 0,30,192 17 2838 . A <*> 0 . DP=9;I16=4,5,0,0,290,9988,0,0,540,32400,0,0,168,3546,0,0;QS=1,0;MQ0F=0 PL 0,27,220 17 2839 . G <*> 0 . DP=9;I16=4,5,0,0,280,9556,0,0,540,32400,0,0,168,3518,0,0;QS=1,0;MQ0F=0 PL 0,27,212 17 2840 . C <*> 0 . DP=9;I16=4,5,0,0,304,10652,0,0,540,32400,0,0,168,3502,0,0;QS=1,0;MQ0F=0 PL 0,27,227 17 2841 . A <*> 0 . DP=9;I16=4,5,0,0,310,11656,0,0,540,32400,0,0,167,3449,0,0;QS=1,0;MQ0F=0 PL 0,27,237 17 2842 . G <*> 0 . DP=9;I16=4,5,0,0,310,11124,0,0,540,32400,0,0,165,3361,0,0;QS=1,0;MQ0F=0 PL 0,27,233 17 2843 . C <*> 0 . DP=9;I16=4,5,0,0,278,9488,0,0,540,32400,0,0,162,3238,0,0;QS=1,0;MQ0F=0 PL 0,27,212 17 2844 . A <*> 0 . DP=9;I16=4,5,0,0,310,11088,0,0,540,32400,0,0,159,3129,0,0;QS=1,0;MQ0F=0 PL 0,27,231 17 2845 . G <*> 0 . DP=9;I16=4,5,0,0,301,11069,0,0,540,32400,0,0,156,3034,0,0;QS=1,0;MQ0F=0 PL 0,27,228 17 2846 . C <*> 0 . DP=9;I16=4,5,0,0,286,9844,0,0,540,32400,0,0,153,2953,0,0;QS=1,0;MQ0F=0 PL 0,27,217 17 2847 . C <*> 0 . DP=9;I16=4,5,0,0,241,7673,0,0,540,32400,0,0,150,2886,0,0;QS=1,0;MQ0F=0 PL 0,27,187 17 2848 . G <*> 0 . DP=9;I16=3,6,0,0,251,7979,0,0,540,32400,0,0,153,2977,0,0;QS=1,0;MQ0F=0 PL 0,27,189 17 2849 . T <*> 0 . DP=9;I16=3,6,0,0,293,10179,0,0,540,32400,0,0,152,2986,0,0;QS=1,0;MQ0F=0 PL 0,27,210 17 2850 . C <*> 0 . DP=9;I16=3,6,0,0,259,7743,0,0,540,32400,0,0,151,3009,0,0;QS=1,0;MQ0F=0 PL 0,27,188 17 2851 . G <*> 0 . DP=8;I16=2,6,0,0,267,9099,0,0,480,28800,0,0,151,3045,0,0;QS=1,0;MQ0F=0 PL 0,24,194 17 2852 . T <*> 0 . DP=8;I16=2,6,0,0,296,11088,0,0,480,28800,0,0,150,3044,0,0;QS=1,0;MQ0F=0 PL 0,24,214 17 2853 . G <*> 0 . DP=8;I16=2,6,0,0,281,9945,0,0,480,28800,0,0,149,3057,0,0;QS=1,0;MQ0F=0 PL 0,24,202 17 2854 . T <*> 0 . DP=8;I16=2,6,0,0,283,10257,0,0,480,28800,0,0,147,3033,0,0;QS=1,0;MQ0F=0 PL 0,24,207 17 2855 . C <*> 0 . DP=8;I16=2,6,0,0,245,8383,0,0,480,28800,0,0,145,3021,0,0;QS=1,0;MQ0F=0 PL 0,24,186 17 2856 . T <*> 0 . DP=8;I16=2,6,0,0,218,7740,0,0,480,28800,0,0,143,3021,0,0;QS=1,0;MQ0F=0 PL 0,24,174 17 2857 . C <*> 0 . DP=8;I16=2,6,0,0,241,8279,0,0,480,28800,0,0,140,2982,0,0;QS=1,0;MQ0F=0 PL 0,24,185 17 2858 . A <*> 0 . DP=8;I16=2,6,0,0,247,8415,0,0,480,28800,0,0,137,2953,0,0;QS=1,0;MQ0F=0 PL 0,24,188 17 2859 . C <*> 0 . DP=8;I16=2,6,0,0,258,8962,0,0,480,28800,0,0,133,2883,0,0;QS=1,0;MQ0F=0 PL 0,24,194 17 2860 . C <*> 0 . DP=8;I16=2,6,0,0,267,9449,0,0,480,28800,0,0,129,2821,0,0;QS=1,0;MQ0F=0 PL 0,24,200 17 2861 . C <*> 0 . DP=8;I16=2,6,0,0,274,10100,0,0,480,28800,0,0,125,2767,0,0;QS=1,0;MQ0F=0 PL 0,24,205 17 2862 . A <*> 0 . DP=8;I16=2,6,0,0,311,12199,0,0,480,28800,0,0,121,2721,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 2863 . G <*> 0 . DP=7;I16=2,5,0,0,250,9198,0,0,420,25200,0,0,118,2682,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 2864 . G <*> 0 . DP=7;I16=2,5,0,0,235,8639,0,0,420,25200,0,0,115,2649,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 2865 . G <*> 0 . DP=7;I16=2,5,0,0,238,8596,0,0,420,25200,0,0,112,2622,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 2866 . T G,<*> 0 . DP=6;I16=1,4,1,0,179,6567,2,4,300,18000,60,3600,100,2500,10,100;QS=0.978142,0.0218579,0;SGB=-0.379885;RPBZ=0.87831;MQBZ=0;MQSBZ=0;BQBZ=-1.46385;SCBZ=-0.447214;MQ0F=0 PL 0,10,141,15,144,141 17 2867 . G <*> 0 . DP=5;I16=2,3,0,0,172,6102,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2868 . T <*> 0 . DP=5;I16=2,3,0,0,179,6849,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 2869 . C <*> 0 . DP=5;I16=2,3,0,0,189,7277,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 2870 . T <*> 0 . DP=5;I16=2,3,0,0,203,8273,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,176 17 2871 . G <*> 0 . DP=5;I16=2,3,0,0,197,7851,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 2872 . A <*> 0 . DP=5;I16=2,3,0,0,196,7770,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 2873 . A <*> 0 . DP=5;I16=2,3,0,0,180,6868,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 2874 . A <*> 0 . DP=5;I16=2,3,0,0,183,7197,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 2875 . C <*> 0 . DP=5;I16=2,3,0,0,189,7331,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2876 . A <*> 0 . DP=5;I16=2,3,0,0,214,9208,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,186 17 2877 . G <*> 0 . DP=4;I16=1,3,0,0,168,7062,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 2878 . A <*> 0 . DP=5;I16=2,3,0,0,190,7328,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2879 . T <*> 0 . DP=5;I16=2,3,0,0,201,8105,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 2880 . G <*> 0 . DP=5;I16=2,3,0,0,199,7949,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 2881 . T <*> 0 . DP=5;I16=2,3,0,0,204,8342,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 2882 . G <*> 0 . DP=5;I16=2,3,0,0,202,8206,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,176 17 2883 . G <*> 0 . DP=5;I16=2,3,0,0,201,8159,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 2884 . A <*> 0 . DP=5;I16=2,3,0,0,208,8710,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,181 17 2885 . G <*> 0 . DP=5;I16=2,3,0,0,209,8767,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,182 17 2886 . G <*> 0 . DP=5;I16=2,3,0,0,196,7708,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 2887 . T <*> 0 . DP=5;I16=2,3,0,0,191,7497,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2888 . C <*> 0 . DP=5;I16=2,3,0,0,182,6796,0,0,300,18000,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 2889 . T <*> 0 . DP=5;I16=2,3,0,0,201,8119,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 2890 . C <*> 0 . DP=5;I16=2,3,0,0,157,5391,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 2891 . G <*> 0 . DP=5;I16=2,3,0,0,165,5981,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 2892 . G <*> 0 . DP=5;I16=2,3,0,0,188,7126,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 2893 . G <*> 0 . DP=5;I16=2,3,0,0,172,6100,0,0,300,18000,0,0,114,2676,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2894 . T <*> 0 . DP=5;I16=2,3,0,0,179,6531,0,0,300,18000,0,0,114,2660,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 2895 . G <*> 0 . DP=5;I16=2,3,0,0,190,7324,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2896 . A <*> 0 . DP=5;I16=2,3,0,0,187,7201,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 2897 . G <*> 0 . DP=5;I16=2,3,0,0,193,7527,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 2898 . G <*> 0 . DP=5;I16=2,3,0,0,194,7564,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 2899 . C <*> 0 . DP=5;I16=2,3,0,0,169,5839,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 2900 . G <*> 0 . DP=5;I16=2,3,0,0,176,6306,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 2901 . T <*> 0 . DP=5;I16=2,3,0,0,190,7286,0,0,300,18000,0,0,114,2660,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 2902 . G <*> 0 . DP=5;I16=2,3,0,0,188,7170,0,0,300,18000,0,0,114,2676,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 2903 . G <*> 0 . DP=5;I16=2,3,0,0,192,7422,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 2904 . C <*> 0 . DP=5;I16=2,3,0,0,195,7621,0,0,300,18000,0,0,112,2620,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 2905 . T <*> 0 . DP=5;I16=2,3,0,0,200,8024,0,0,300,18000,0,0,110,2548,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 2906 . C <*> 0 . DP=5;I16=2,3,0,0,200,8014,0,0,300,18000,0,0,108,2480,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 2907 . A <*> 0 . DP=5;I16=2,3,0,0,195,7791,0,0,300,18000,0,0,105,2367,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 2908 . G <*> 0 . DP=5;I16=2,3,0,0,189,7275,0,0,300,18000,0,0,102,2260,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 2909 . A <*> 0 . DP=5;I16=2,3,0,0,197,7791,0,0,300,18000,0,0,98,2110,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 2910 . T <*> 0 . DP=6;I16=2,4,0,0,194,7380,0,0,360,21600,0,0,119,2593,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 2911 . A <*> 0 . DP=6;I16=2,4,0,0,225,8485,0,0,360,21600,0,0,115,2459,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 2912 . C <*> 0 . DP=6;I16=2,4,0,0,231,8921,0,0,360,21600,0,0,111,2333,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 2913 . A <*> 0 . DP=6;I16=2,4,0,0,243,9863,0,0,360,21600,0,0,107,2215,0,0;QS=1,0;MQ0F=0 PL 0,18,199 17 2914 . G <*> 0 . DP=6;I16=2,4,0,0,229,8783,0,0,360,21600,0,0,103,2105,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 2915 . G <*> 0 . DP=6;I16=2,4,0,0,215,7917,0,0,360,21600,0,0,99,2003,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2916 . G <*> 0 . DP=6;I16=2,4,0,0,189,6551,0,0,360,21600,0,0,95,1909,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 2917 . A <*> 0 . DP=6;I16=2,4,0,0,216,7940,0,0,360,21600,0,0,91,1823,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2918 . G <*> 0 . DP=6;I16=3,3,0,0,202,6878,0,0,360,21600,0,0,88,1744,0,0;QS=1,0;MQ0F=0 PL 0,18,170 17 2919 . T <*> 0 . DP=6;I16=3,3,0,0,211,7509,0,0,360,21600,0,0,86,1672,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 2920 . G <*> 0 . DP=6;I16=3,3,0,0,216,7790,0,0,360,21600,0,0,84,1608,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 2921 . G <*> 0 . DP=6;I16=3,3,0,0,209,7351,0,0,360,21600,0,0,82,1552,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 2922 . C <*> 0 . DP=6;I16=3,3,0,0,205,7125,0,0,360,21600,0,0,80,1504,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 2923 . C <*> 0 . DP=6;I16=3,3,0,0,208,7312,0,0,360,21600,0,0,78,1464,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 2924 . C <*> 0 . DP=6;I16=3,3,0,0,219,8075,0,0,360,21600,0,0,76,1432,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 2925 . A <*> 0 . DP=6;I16=3,3,0,0,226,8516,0,0,360,21600,0,0,74,1408,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 2926 . C <*> 0 . DP=6;I16=3,3,0,0,209,7307,0,0,360,21600,0,0,72,1392,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 2927 . A <*> 0 . DP=6;I16=3,3,0,0,227,8675,0,0,360,21600,0,0,70,1384,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 2928 . G <*> 0 . DP=6;I16=3,3,0,0,192,6208,0,0,360,21600,0,0,68,1384,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 2929 . C <*> 0 . DP=5;I16=3,2,0,0,171,6015,0,0,300,18000,0,0,67,1391,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 2930 . T <*> 0 . DP=5;I16=3,2,0,0,180,6622,0,0,300,18000,0,0,66,1404,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 2931 . C <*> 0 . DP=5;I16=3,2,0,0,161,5367,0,0,300,18000,0,0,65,1423,0,0;QS=1,0;MQ0F=0 PL 0,15,140 17 2932 . G <*> 0 . DP=4;I16=2,2,0,0,127,4237,0,0,240,14400,0,0,65,1447,0,0;QS=1,0;MQ0F=0 PL 0,12,117 17 2933 . G <*> 0 . DP=4;I16=2,2,0,0,126,4124,0,0,240,14400,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 2934 . C <*> 0 . DP=3;I16=2,1,0,0,110,4052,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 2935 . C <*> 0 . DP=3;I16=2,1,0,0,99,3353,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 2936 . T <*> 0 . DP=3;I16=2,1,0,0,104,3654,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 2937 . G <*> 0 . DP=3;I16=2,1,0,0,84,2574,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,79 17 2938 . T <*> 0 . DP=3;I16=2,1,0,0,107,3865,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,101 17 2939 . C <*> 0 . DP=3;I16=2,1,0,0,112,4210,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 2940 . T <*> 0 . DP=3;I16=2,1,0,0,116,4534,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 2941 . T <*> 0 . DP=3;I16=2,1,0,0,104,3650,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 2942 . T <*> 0 . DP=3;I16=2,1,0,0,106,3780,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 2943 . G <*> 0 . DP=3;I16=2,1,0,0,91,2861,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,86 17 2944 . A <*> 0 . DP=3;I16=2,1,0,0,118,4646,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 2945 . A <*> 0 . DP=3;I16=2,1,0,0,113,4277,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 2946 . A <*> 0 . DP=3;I16=2,1,0,0,114,4334,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 2947 . G <*> 0 . DP=3;I16=2,1,0,0,82,2302,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 2948 . G <*> 0 . DP=4;I16=2,2,0,0,127,4081,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 2949 . C <*> 0 . DP=4;I16=2,2,0,0,135,4697,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 2950 . C <*> 0 . DP=4;I16=2,2,0,0,124,4138,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 2951 . A <*> 0 . DP=4;I16=2,2,0,0,146,5346,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 2952 . C <*> 0 . DP=4;I16=2,2,0,0,122,3860,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 2953 . G <*> 0 . DP=4;I16=2,2,0,0,121,3765,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQ0F=0 PL 0,12,111 17 2954 . T <*> 0 . DP=4;I16=2,2,0,0,148,5584,0,0,240,14400,0,0,80,1862,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 2955 . G <*> 0 . DP=4;I16=2,2,0,0,138,4830,0,0,240,14400,0,0,80,1828,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 2956 . A <*> 0 . DP=4;I16=2,2,0,0,137,4833,0,0,240,14400,0,0,80,1798,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2957 . C <*> 0 . DP=4;I16=2,2,0,0,118,4122,0,0,240,14400,0,0,80,1772,0,0;QS=1,0;MQ0F=0 PL 0,12,109 17 2958 . C <*> 0 . DP=4;I16=2,2,0,0,148,5506,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 2959 . T <*> 0 . DP=4;I16=2,2,0,0,152,5852,0,0,240,14400,0,0,80,1732,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 2960 . G <*> 0 . DP=4;I16=2,2,0,0,136,4890,0,0,240,14400,0,0,80,1718,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2961 . G <*> 0 . DP=4;I16=2,2,0,0,122,4602,0,0,240,14400,0,0,79,1659,0,0;QS=1,0;MQ0F=0 PL 0,12,113 17 2962 . C <*> 0 . DP=4;I16=2,2,0,0,144,5288,0,0,240,14400,0,0,78,1606,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 2963 . C <*> 0 . DP=4;I16=2,2,0,0,115,3855,0,0,240,14400,0,0,77,1559,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 2964 . C <*> 0 . DP=5;I16=3,2,0,0,173,6043,0,0,300,18000,0,0,76,1518,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 2965 . A <*> 0 . DP=5;I16=3,2,0,0,178,6448,0,0,300,18000,0,0,76,1484,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 2966 . C <*> 0 . DP=5;I16=3,2,0,0,163,5467,0,0,300,18000,0,0,76,1458,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2967 . G <*> 0 . DP=6;I16=3,3,0,0,160,4500,0,0,360,21600,0,0,76,1440,0,0;QS=1,0;MQ0F=0 PL 0,18,135 17 2968 . G <*> 0 . DP=6;I16=3,3,0,0,191,6355,0,0,360,21600,0,0,77,1431,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 2969 . C <*> 0 . DP=6;I16=3,3,0,0,217,7875,0,0,360,21600,0,0,78,1432,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 2970 . T <*> 0 . DP=6;I16=3,3,0,0,227,8599,0,0,360,21600,0,0,79,1443,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 2971 . G <*> 0 . DP=6;I16=3,3,0,0,220,8082,0,0,360,21600,0,0,80,1464,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 2972 . G <*> 0 . DP=6;I16=3,3,0,0,193,6229,0,0,360,21600,0,0,81,1495,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 2973 . C <*> 0 . DP=6;I16=3,3,0,0,198,6572,0,0,360,21600,0,0,82,1536,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 2974 . A <*> 0 . DP=6;I16=3,3,0,0,208,7252,0,0,360,21600,0,0,82,1536,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 2975 . G <*> 0 . DP=6;I16=3,3,0,0,197,6675,0,0,360,21600,0,0,82,1544,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 2976 . G <*> 0 . DP=6;I16=3,3,0,0,202,6958,0,0,360,21600,0,0,82,1560,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 2977 . T <*> 0 . DP=6;I16=3,3,0,0,183,5889,0,0,360,21600,0,0,82,1584,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 2978 . G <*> 0 . DP=6;I16=3,3,0,0,201,6951,0,0,360,21600,0,0,82,1616,0,0;QS=1,0;MQ0F=0 PL 0,18,170 17 2979 . G <*> 0 . DP=5;I16=2,3,0,0,162,5406,0,0,300,18000,0,0,83,1655,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2980 . G <*> 0 . DP=5;I16=2,3,0,0,168,5842,0,0,300,18000,0,0,84,1700,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 2981 . A <*> 0 . DP=5;I16=2,3,0,0,173,6031,0,0,300,18000,0,0,85,1751,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 2982 . C <*> 0 . DP=5;I16=2,3,0,0,166,5634,0,0,300,18000,0,0,86,1808,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 2983 . C <*> 0 . DP=5;I16=2,3,0,0,161,5459,0,0,300,18000,0,0,87,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 2984 . C <*> 0 . DP=5;I16=2,3,0,0,179,6549,0,0,300,18000,0,0,88,1940,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 2985 . A <*> 0 . DP=5;I16=2,3,0,0,173,6069,0,0,300,18000,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 2986 . G <*> 0 . DP=4;I16=2,2,0,0,137,4835,0,0,240,14400,0,0,91,2095,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 2987 . C <*> 0 . DP=4;I16=2,2,0,0,145,5263,0,0,240,14400,0,0,93,2179,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 2988 . T <*> 0 . DP=4;I16=2,2,0,0,148,5586,0,0,240,14400,0,0,95,2267,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 2989 . G <*> 0 . DP=4;I16=2,2,0,0,136,4764,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 2990 . C <*> 0 . DP=4;I16=2,2,0,0,140,4970,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 2991 . A <*> 0 . DP=4;I16=2,2,0,0,143,5197,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 2992 . G <*> 0 . DP=4;I16=2,2,0,0,131,4581,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 2993 . G <*> 0 . DP=4;I16=2,2,0,0,134,4698,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 2994 . G <*> 0 . DP=4;I16=2,2,0,0,127,4217,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 2995 . G <*> 0 . DP=4;I16=2,2,0,0,146,5388,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 2996 . T G,<*> 0 . DP=4;I16=1,2,1,0,114,4428,1,1,180,10800,60,3600,75,1875,22,484;QS=0.966102,0.0338983,0;SGB=-0.379885;RPBZ=1.34164;MQBZ=0;MQSBZ=0;BQBZ=-1.41421;SCBZ=0;MQ0F=0 PL 0,5,101,9,104,101 17 2997 . C <*> 0 . DP=4;I16=2,2,0,0,125,4001,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,115 17 2998 . C <*> 0 . DP=4;I16=2,2,0,0,134,4610,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 2999 . A <*> 0 . DP=4;I16=2,2,0,0,148,5574,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 3000 . G <*> 0 . DP=4;I16=2,2,0,0,147,5495,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3001 . C <*> 0 . DP=4;I16=2,2,0,0,139,4971,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3002 . A <*> 0 . DP=4;I16=2,2,0,0,151,5779,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3003 . G <*> 0 . DP=4;I16=2,2,0,0,131,4365,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 3004 . C <*> 0 . DP=4;I16=2,2,0,0,141,5039,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 3005 . A <*> 0 . DP=4;I16=2,2,0,0,136,4674,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 3006 . C <*> 0 . DP=4;I16=2,2,0,0,148,5496,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3007 . C <*> 0 . DP=4;I16=2,2,0,0,157,6187,0,0,240,14400,0,0,86,1996,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 3008 . C <*> 0 . DP=4;I16=2,2,0,0,158,6270,0,0,240,14400,0,0,85,1975,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 3009 . A <*> 0 . DP=4;I16=2,2,0,0,142,5116,0,0,240,14400,0,0,84,1956,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 3010 . C <*> 0 . DP=4;I16=2,2,0,0,147,5445,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3011 . A <*> 0 . DP=4;I16=2,2,0,0,158,6254,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 3012 . G <*> 0 . DP=4;I16=2,2,0,0,155,6017,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3013 . C <*> 0 . DP=4;I16=2,2,0,0,154,5946,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3014 . A <*> 0 . DP=4;I16=2,2,0,0,154,5988,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3015 . G <*> 0 . DP=4;I16=2,2,0,0,143,5143,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3016 . C <*> 0 . DP=4;I16=2,2,0,0,144,5214,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3017 . C <*> 0 . DP=4;I16=2,2,0,0,138,4820,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3018 . A <*> 0 . DP=4;I16=2,2,0,0,88,2490,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,83 17 3019 . C <*> 0 . DP=3;I16=1,2,0,0,110,4052,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 3020 . C <*> 0 . DP=3;I16=1,2,0,0,121,4889,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,114 17 3021 . T <*> 0 . DP=3;I16=1,2,0,0,116,4506,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 3022 . G <*> 0 . DP=3;I16=1,2,0,0,116,4506,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 3023 . T <*> 0 . DP=3;I16=1,2,0,0,117,4571,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 3024 . G <*> 0 . DP=3;I16=1,2,0,0,120,4814,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 3025 . G <*> 0 . DP=3;I16=1,2,0,0,116,4554,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 3026 . C <*> 0 . DP=3;I16=1,2,0,0,114,4346,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 3027 . A <*> 0 . DP=3;I16=1,2,0,0,115,4469,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 3028 . G <*> 0 . DP=3;I16=1,2,0,0,114,4430,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,107 17 3029 . G <*> 0 . DP=3;I16=1,2,0,0,115,4441,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,109 17 3030 . G <*> 0 . DP=3;I16=1,2,0,0,112,4202,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 3031 . A <*> 0 . DP=3;I16=1,2,0,0,120,4826,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 3032 . G <*> 0 . DP=3;I16=1,2,0,0,113,4325,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 3033 . G <*> 0 . DP=3;I16=1,2,0,0,113,4285,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 3034 . A <*> 0 . DP=4;I16=2,2,0,0,137,4921,0,0,240,14400,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3035 . G <*> 0 . DP=4;I16=2,2,0,0,140,5006,0,0,240,14400,0,0,64,1420,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3036 . C <*> 0 . DP=4;I16=2,2,0,0,153,5879,0,0,240,14400,0,0,64,1398,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3037 . T <*> 0 . DP=4;I16=2,2,0,0,156,6110,0,0,240,14400,0,0,64,1380,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 3038 . T <*> 0 . DP=4;I16=2,2,0,0,137,4711,0,0,240,14400,0,0,64,1366,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 3039 . G <*> 0 . DP=4;I16=2,2,0,0,139,4887,0,0,240,14400,0,0,64,1356,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 3040 . T <*> 0 . DP=4;I16=2,2,0,0,142,5102,0,0,240,14400,0,0,63,1301,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 3041 . G <*> 0 . DP=4;I16=2,2,0,0,147,5435,0,0,240,14400,0,0,62,1252,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3042 . G <*> 0 . DP=4;I16=2,2,0,0,131,4313,0,0,240,14400,0,0,61,1209,0,0;QS=1,0;MQ0F=0 PL 0,12,120 17 3043 . T <*> 0 . DP=4;I16=2,2,0,0,135,4779,0,0,240,14400,0,0,59,1123,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 3044 . A <*> 0 . DP=4;I16=2,2,0,0,136,4668,0,0,240,14400,0,0,57,1045,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 3045 . C <*> 0 . DP=4;I16=2,2,0,0,132,4622,0,0,240,14400,0,0,55,975,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 3046 . A <*> 0 . DP=4;I16=2,2,0,0,154,5974,0,0,240,14400,0,0,53,913,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3047 . G <*> 0 . DP=4;I16=2,2,0,0,141,5003,0,0,240,14400,0,0,51,859,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 3048 . T <*> 0 . DP=4;I16=2,2,0,0,141,5019,0,0,240,14400,0,0,49,813,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 3049 . G <*> 0 . DP=3;I16=2,1,0,0,111,4109,0,0,180,10800,0,0,48,774,0,0;QS=1,0;MQ0F=0 PL 0,9,105 17 3050 . G <*> 0 . DP=3;I16=2,1,0,0,106,3770,0,0,180,10800,0,0,47,741,0,0;QS=1,0;MQ0F=0 PL 0,9,100 17 3051 . A <*> 0 . DP=3;I16=2,1,0,0,109,3989,0,0,180,10800,0,0,46,714,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 3052 . C <*> 0 . DP=3;I16=2,1,0,0,97,3331,0,0,180,10800,0,0,45,693,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 3053 . A <*> 0 . DP=3;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,44,678,0,0;QS=1,0;MQ0F=0 PL 0,9,110 17 3054 . G <*> 0 . DP=3;I16=2,1,0,0,103,3811,0,0,180,10800,0,0,43,669,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 3055 . G <*> 0 . DP=4;I16=2,2,0,0,113,4173,0,0,240,14400,0,0,67,1291,0,0;QS=1,0;MQ0F=0 PL 0,12,107 17 3056 . C <*> 0 . DP=4;I16=2,2,0,0,132,4642,0,0,240,14400,0,0,66,1294,0,0;QS=1,0;MQ0F=0 PL 0,12,122 17 3057 . C <*> 0 . DP=4;I16=2,2,0,0,105,3419,0,0,240,14400,0,0,65,1303,0,0;QS=1,0;MQ0F=0 PL 0,12,99 17 3058 . C <*> 0 . DP=4;I16=2,2,0,0,125,4207,0,0,240,14400,0,0,64,1318,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 3059 . T <*> 0 . DP=4;I16=2,2,0,0,109,3705,0,0,240,14400,0,0,63,1339,0,0;QS=1,0;MQ0F=0 PL 0,12,103 17 3060 . G C,<*> 0 . DP=5;I16=2,2,0,1,126,4164,2,4,240,14400,60,3600,61,1315,25,625;QS=0.969231,0.0307692,0;SGB=-0.379885;RPBZ=-1.41421;MQBZ=0;MQSBZ=0;BQBZ=-1.41421;SCBZ=1.22474;MQ0F=0 PL 0,8,110,12,113,110 17 3061 . C <*> 0 . DP=5;I16=2,3,0,0,164,5458,0,0,300,18000,0,0,84,1920,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 3062 . C <*> 0 . DP=5;I16=2,3,0,0,153,4913,0,0,300,18000,0,0,82,1904,0,0;QS=1,0;MQ0F=0 PL 0,15,134 17 3063 . C <*> 0 . DP=5;I16=2,3,0,0,149,4995,0,0,300,18000,0,0,80,1892,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 3064 . A <*> 0 . DP=5;I16=2,3,0,0,164,5622,0,0,300,18000,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 3065 . G <*> 0 . DP=4;I16=1,3,0,0,132,4526,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,118 17 3066 . A <*> 0 . DP=4;I16=1,3,0,0,115,3749,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 3067 . T <*> 0 . DP=4;I16=1,3,0,0,114,3570,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,103 17 3068 . G <*> 0 . DP=3;I16=1,2,0,0,88,2790,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 3069 . G C,<*> 0 . DP=3;I16=1,1,0,1,57,1889,1,1,120,7200,60,3600,50,1250,25,625;QS=0.934426,0.0655738,0;SGB=-0.379885;RPBZ=-1.22474;MQBZ=0;MQSBZ=0;BQBZ=-1.22474;SCBZ=1.22474;MQ0F=0 PL 0,3,51,6,54,52 17 3070 . C <*> 0 . DP=3;I16=1,2,0,0,100,3454,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 3071 . C <*> 0 . DP=3;I16=1,2,0,0,104,3656,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 3072 . C <*> 0 . DP=3;I16=1,2,0,0,112,4230,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,106 17 3073 . C <*> 0 . DP=3;I16=1,2,0,0,122,4986,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 3074 . C <*> 0 . DP=3;I16=1,2,0,0,123,5057,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,116 17 3075 . C <*> 0 . DP=3;I16=1,2,0,0,99,3461,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 3076 . G <*> 0 . DP=3;I16=1,2,0,0,96,3098,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 3077 . C <*> 0 . DP=3;I16=1,2,0,0,117,4619,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 3078 . C <*> 0 . DP=3;I16=1,2,0,0,117,4605,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,111 17 3079 . T <*> 0 . DP=3;I16=1,2,0,0,123,5061,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,116 17 3080 . G <*> 0 . DP=3;I16=1,2,0,0,109,4021,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 3081 . C <*> 0 . DP=3;I16=1,2,0,0,97,3221,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,92 17 3082 . C <*> 0 . DP=3;I16=1,2,0,0,119,4721,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,112 17 3083 . T <*> 0 . DP=3;I16=1,2,0,0,120,4824,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,113 17 3084 . G <*> 0 . DP=4;I16=1,3,0,0,153,5887,0,0,240,14400,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3085 . T <*> 0 . DP=4;I16=1,3,0,0,153,5857,0,0,240,14400,0,0,69,1575,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3086 . G <*> 0 . DP=4;I16=1,3,0,0,149,5569,0,0,240,14400,0,0,69,1543,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3087 . G <*> 0 . DP=4;I16=1,3,0,0,155,6031,0,0,240,14400,0,0,69,1515,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 3088 . A <*> 0 . DP=4;I16=1,3,0,0,154,5956,0,0,240,14400,0,0,69,1491,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3089 . A <*> 0 . DP=5;I16=2,3,0,0,202,8232,0,0,300,18000,0,0,69,1471,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 3090 . G <*> 0 . DP=5;I16=2,3,0,0,185,6855,0,0,300,18000,0,0,70,1456,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 3091 . T <*> 0 . DP=5;I16=2,3,0,0,174,6552,0,0,300,18000,0,0,71,1447,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 3092 . T <*> 0 . DP=5;I16=2,3,0,0,189,7193,0,0,300,18000,0,0,72,1444,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3093 . G <*> 0 . DP=5;I16=2,3,0,0,179,6575,0,0,300,18000,0,0,73,1447,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3094 . A <*> 0 . DP=5;I16=2,3,0,0,185,6961,0,0,300,18000,0,0,74,1456,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3095 . C <*> 0 . DP=5;I16=2,3,0,0,188,7122,0,0,300,18000,0,0,75,1471,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 3096 . C <*> 0 . DP=5;I16=2,3,0,0,193,7465,0,0,300,18000,0,0,76,1492,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3097 . A <*> 0 . DP=5;I16=2,3,0,0,200,8034,0,0,300,18000,0,0,77,1519,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 3098 . G <*> 0 . DP=5;I16=2,3,0,0,191,7333,0,0,300,18000,0,0,78,1552,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 3099 . A <*> 0 . DP=5;I16=2,3,0,0,191,7299,0,0,300,18000,0,0,78,1542,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3100 . C <*> 0 . DP=5;I16=2,3,0,0,184,6802,0,0,300,18000,0,0,78,1540,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 3101 . C <*> 0 . DP=5;I16=2,3,0,0,186,6930,0,0,300,18000,0,0,78,1546,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3102 . A <*> 0 . DP=6;I16=3,3,0,0,226,8548,0,0,360,21600,0,0,78,1560,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3103 . T <*> 0 . DP=6;I16=3,3,0,0,223,8347,0,0,360,21600,0,0,79,1583,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3104 . C T,<*> 0 . DP=5;I16=1,2,2,0,114,4334,80,3202,180,10800,120,7200,41,765,40,850;QS=0.587629,0.412371,0;VDB=0.78;SGB=-0.453602;RPBZ=0.296174;MQBZ=0;MQSBZ=0;BQBZ=1.48087;SCBZ=-0.816497;MQ0F=0 PL 59,0,93,68,99,157 17 3105 . T <*> 0 . DP=5;I16=3,2,0,0,195,7621,0,0,300,18000,0,0,83,1655,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3106 . G <*> 0 . DP=5;I16=3,2,0,0,193,7461,0,0,300,18000,0,0,85,1703,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3107 . T <*> 0 . DP=6;I16=3,3,0,0,233,9067,0,0,360,21600,0,0,87,1759,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3108 . C <*> 0 . DP=6;I16=3,3,0,0,226,8562,0,0,360,21600,0,0,90,1824,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3109 . A <*> 0 . DP=6;I16=3,3,0,0,234,9146,0,0,360,21600,0,0,93,1899,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3110 . C <*> 0 . DP=6;I16=3,3,0,0,226,8534,0,0,360,21600,0,0,94,1884,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3111 . A <*> 0 . DP=6;I16=3,3,0,0,244,10014,0,0,360,21600,0,0,95,1879,0,0;QS=1,0;MQ0F=0 PL 0,18,205 17 3112 . G <*> 0 . DP=6;I16=3,3,0,0,227,8745,0,0,360,21600,0,0,96,1884,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 3113 . C <*> 0 . DP=6;I16=3,3,0,0,231,8947,0,0,360,21600,0,0,97,1899,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 3114 . A <*> 0 . DP=6;I16=3,3,0,0,239,9559,0,0,360,21600,0,0,98,1924,0,0;QS=1,0;MQ0F=0 PL 0,18,200 17 3115 . G <*> 0 . DP=6;I16=3,3,0,0,233,9095,0,0,360,21600,0,0,98,1908,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3116 . G <*> 0 . DP=6;I16=3,3,0,0,232,9014,0,0,360,21600,0,0,98,1900,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3117 . T <*> 0 . DP=6;I16=3,3,0,0,209,7553,0,0,360,21600,0,0,98,1900,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 3118 . A <*> 0 . DP=6;I16=3,3,0,0,231,8907,0,0,360,21600,0,0,98,1908,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 3119 . A <*> 0 . DP=6;I16=3,3,0,0,248,10278,0,0,360,21600,0,0,98,1924,0,0;QS=1,0;MQ0F=0 PL 0,18,207 17 3120 . G <*> 0 . DP=6;I16=3,3,0,0,217,7947,0,0,360,21600,0,0,98,1948,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 3121 . A <*> 0 . DP=6;I16=3,3,0,0,232,9014,0,0,360,21600,0,0,98,1980,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3122 . C <*> 0 . DP=6;I16=3,3,0,0,229,8779,0,0,360,21600,0,0,98,2020,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3123 . T <*> 0 . DP=6;I16=3,3,0,0,242,9864,0,0,360,21600,0,0,98,2068,0,0;QS=1,0;MQ0F=0 PL 0,18,204 17 3124 . C <*> 0 . DP=5;I16=3,2,0,0,206,8500,0,0,300,18000,0,0,99,2123,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3125 . T <*> 0 . DP=5;I16=3,2,0,0,213,9081,0,0,300,18000,0,0,100,2184,0,0;QS=1,0;MQ0F=0 PL 0,15,185 17 3126 . G <*> 0 . DP=5;I16=3,2,0,0,201,8093,0,0,300,18000,0,0,101,2251,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 3127 . C <*> 0 . DP=5;I16=3,2,0,0,202,8174,0,0,300,18000,0,0,102,2324,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 3128 . T <*> 0 . DP=5;I16=3,2,0,0,209,8753,0,0,300,18000,0,0,102,2352,0,0;QS=1,0;MQ0F=0 PL 0,15,182 17 3129 . T <*> 0 . DP=5;I16=3,2,0,0,206,8506,0,0,300,18000,0,0,102,2384,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3130 . T <*> 0 . DP=5;I16=3,2,0,0,195,7663,0,0,300,18000,0,0,102,2420,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3131 . C <*> 0 . DP=5;I16=3,2,0,0,196,7724,0,0,300,18000,0,0,102,2460,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 3132 . T <*> 0 . DP=5;I16=3,2,0,0,200,8048,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 3133 . G <*> 0 . DP=5;I16=3,2,0,0,198,7860,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 3134 . G <*> 0 . DP=5;I16=3,2,0,0,191,7397,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3135 . G <*> 0 . DP=4;I16=2,2,0,0,165,6819,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,151 17 3136 . C <*> 0 . DP=4;I16=2,2,0,0,153,5945,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3137 . A <*> 0 . DP=4;I16=2,2,0,0,155,6037,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 3138 . A <*> 0 . DP=4;I16=2,2,0,0,161,6523,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,147 17 3139 . C <*> 0 . DP=4;I16=2,2,0,0,152,5790,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3140 . C <*> 0 . DP=4;I16=2,2,0,0,159,6365,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,145 17 3141 . C <*> 0 . DP=4;I16=2,2,0,0,163,6705,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 3142 . A <*> 0 . DP=4;I16=2,2,0,0,169,7149,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,155 17 3143 . G <*> 0 . DP=4;I16=2,2,0,0,165,6825,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,151 17 3144 . C <*> 0 . DP=5;I16=3,2,0,0,190,7296,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3145 . A <*> 0 . DP=5;I16=3,2,0,0,200,8046,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 3146 . G <*> 0 . DP=5;I16=3,2,0,0,206,8530,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,179 17 3147 . G <*> 0 . DP=5;I16=3,2,0,0,198,7910,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 3148 . T <*> 0 . DP=5;I16=3,2,0,0,169,5971,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 3149 . G <*> 0 . DP=5;I16=3,2,0,0,192,7406,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3150 . A <*> 0 . DP=5;I16=3,2,0,0,190,7414,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3151 . C <*> 0 . DP=5;I16=3,2,0,0,188,7090,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 3152 . C <*> 0 . DP=5;I16=3,2,0,0,177,6411,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 3153 . C <*> 0 . DP=5;I16=3,2,0,0,190,7326,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 3154 . T <*> 0 . DP=6;I16=4,2,0,0,235,9351,0,0,360,21600,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3155 . G <*> 0 . DP=6;I16=4,2,0,0,220,8160,0,0,360,21600,0,0,112,2622,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 3156 . G <*> 0 . DP=6;I16=4,2,0,0,230,8940,0,0,360,21600,0,0,114,2648,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3157 . A <*> 0 . DP=6;I16=4,2,0,0,235,9261,0,0,360,21600,0,0,116,2678,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 3158 . A <*> 0 . DP=6;I16=4,2,0,0,235,9263,0,0,360,21600,0,0,118,2712,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3159 . T <*> 0 . DP=6;I16=4,2,0,0,236,9366,0,0,360,21600,0,0,120,2750,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3160 . T <*> 0 . DP=6;I16=4,2,0,0,233,9325,0,0,360,21600,0,0,121,2743,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 3161 . C <*> 0 . DP=6;I16=4,2,0,0,239,9617,0,0,360,21600,0,0,122,2742,0,0;QS=1,0;MQ0F=0 PL 0,18,196 17 3162 . C <*> 0 . DP=6;I16=4,2,0,0,227,8857,0,0,360,21600,0,0,123,2747,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3163 . T <*> 0 . DP=6;I16=4,2,0,0,242,9898,0,0,360,21600,0,0,124,2758,0,0;QS=1,0;MQ0F=0 PL 0,18,200 17 3164 . G <*> 0 . DP=6;I16=4,2,0,0,229,8893,0,0,360,21600,0,0,125,2775,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3165 . T <*> 0 . DP=6;I16=4,2,0,0,232,9004,0,0,360,21600,0,0,125,2749,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3166 . C <*> 0 . DP=6;I16=4,2,0,0,238,9460,0,0,360,21600,0,0,125,2731,0,0;QS=1,0;MQ0F=0 PL 0,18,193 17 3167 . C <*> 0 . DP=6;I16=4,2,0,0,230,8932,0,0,360,21600,0,0,125,2721,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3168 . A <*> 0 . DP=6;I16=4,2,0,0,236,9292,0,0,360,21600,0,0,125,2719,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3169 . T <*> 0 . DP=6;I16=4,2,0,0,229,8803,0,0,360,21600,0,0,125,2725,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3170 . C <*> 0 . DP=6;I16=4,2,0,0,246,10098,0,0,360,21600,0,0,124,2688,0,0;QS=1,0;MQ0F=0 PL 0,18,201 17 3171 . T <*> 0 . DP=6;I16=4,2,0,0,245,10039,0,0,360,21600,0,0,123,2657,0,0;QS=1,0;MQ0F=0 PL 0,18,201 17 3172 . G <*> 0 . DP=6;I16=4,2,0,0,213,7757,0,0,360,21600,0,0,122,2632,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 3173 . G <*> 0 . DP=6;I16=4,2,0,0,211,7615,0,0,360,21600,0,0,121,2613,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 3174 . C <*> 0 . DP=6;I16=4,2,0,0,237,9423,0,0,360,21600,0,0,120,2600,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3175 . A <*> 0 . DP=7;I16=5,2,0,0,271,10615,0,0,420,25200,0,0,119,2593,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3176 . G <*> 0 . DP=7;I16=5,2,0,0,268,10330,0,0,420,25200,0,0,119,2593,0,0;QS=1,0;MQ0F=0 PL 0,21,205 17 3177 . G <*> 0 . DP=7;I16=5,2,0,0,252,9250,0,0,420,25200,0,0,119,2601,0,0;QS=1,0;MQ0F=0 PL 0,21,195 17 3178 . T <*> 0 . DP=7;I16=5,2,0,0,222,7256,0,0,420,25200,0,0,118,2568,0,0;QS=1,0;MQ0F=0 PL 0,21,173 17 3179 . G <*> 0 . DP=7;I16=5,2,0,0,243,8581,0,0,420,25200,0,0,117,2545,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 3180 . G <*> 0 . DP=7;I16=5,2,0,0,225,7415,0,0,420,25200,0,0,115,2481,0,0;QS=1,0;MQ0F=0 PL 0,21,175 17 3181 . G <*> 0 . DP=7;I16=5,2,0,0,252,9126,0,0,420,25200,0,0,113,2425,0,0;QS=1,0;MQ0F=0 PL 0,21,193 17 3182 . C <*> 0 . DP=7;I16=5,2,0,0,239,8287,0,0,420,25200,0,0,111,2377,0,0;QS=1,0;MQ0F=0 PL 0,21,184 17 3183 . A <*> 0 . DP=7;I16=5,2,0,0,248,8966,0,0,420,25200,0,0,108,2288,0,0;QS=1,0;MQ0F=0 PL 0,21,193 17 3184 . T <*> 0 . DP=7;I16=5,2,0,0,254,9354,0,0,420,25200,0,0,105,2209,0,0;QS=1,0;MQ0F=0 PL 0,21,196 17 3185 . T <*> 0 . DP=6;I16=5,1,0,0,231,8911,0,0,360,21600,0,0,103,2139,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 3186 . G <*> 0 . DP=6;I16=5,1,0,0,221,8275,0,0,360,21600,0,0,101,2077,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 3187 . A <*> 0 . DP=6;I16=5,1,0,0,225,8531,0,0,360,21600,0,0,99,2023,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 3188 . A <*> 0 . DP=6;I16=5,1,0,0,236,9288,0,0,360,21600,0,0,97,1977,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 3189 . A <*> 0 . DP=6;I16=5,1,0,0,231,8957,0,0,360,21600,0,0,95,1939,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 3190 . C <*> 0 . DP=5;I16=4,1,0,0,182,6662,0,0,300,18000,0,0,94,1908,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 3191 . T <*> 0 . DP=5;I16=4,1,0,0,209,8749,0,0,300,18000,0,0,93,1883,0,0;QS=1,0;MQ0F=0 PL 0,15,171 17 3192 . G <*> 0 . DP=5;I16=4,1,0,0,186,6978,0,0,300,18000,0,0,92,1864,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3193 . G <*> 0 . DP=5;I16=4,1,0,0,181,6633,0,0,300,18000,0,0,91,1851,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 3194 . T <*> 0 . DP=6;I16=4,2,0,0,217,7947,0,0,360,21600,0,0,90,1844,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 3195 . T <*> 0 . DP=6;I16=4,2,0,0,233,9107,0,0,360,21600,0,0,90,1844,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 3196 . T <*> 0 . DP=6;I16=4,2,0,0,229,8811,0,0,360,21600,0,0,90,1852,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3197 . A <*> 0 . DP=6;I16=4,2,0,0,219,8029,0,0,360,21600,0,0,90,1868,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3198 . A <*> 0 . DP=6;I16=4,2,0,0,243,9855,0,0,360,21600,0,0,90,1892,0,0;QS=1,0;MQ0F=0 PL 0,18,198 17 3199 . A <*> 0 . DP=6;I16=4,2,0,0,240,9620,0,0,360,21600,0,0,90,1924,0,0;QS=1,0;MQ0F=0 PL 0,18,196 17 3200 . A <*> 0 . DP=6;I16=4,2,0,0,238,9490,0,0,360,21600,0,0,90,1964,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3201 . A <*> 0 . DP=6;I16=4,2,0,0,242,9796,0,0,360,21600,0,0,89,1961,0,0;QS=1,0;MQ0F=0 PL 0,18,198 17 3202 . T <*> 0 . DP=6;I16=4,2,0,0,227,8733,0,0,360,21600,0,0,88,1964,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3203 . G <*> 0 . DP=5;I16=3,2,0,0,185,6875,0,0,300,18000,0,0,88,1972,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 3204 . T <*> 0 . DP=5;I16=3,2,0,0,195,7631,0,0,300,18000,0,0,88,1984,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3205 . C <*> 0 . DP=5;I16=3,2,0,0,181,6571,0,0,300,18000,0,0,88,2000,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3206 . A <*> 0 . DP=5;I16=3,2,0,0,192,7392,0,0,300,18000,0,0,88,2020,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 3207 . C <*> 0 . DP=5;I16=3,2,0,0,182,6686,0,0,300,18000,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3208 . A <*> 0 . DP=4;I16=3,1,0,0,162,6570,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 3209 . C <*> 0 . DP=4;I16=3,1,0,0,153,5879,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 3210 . C <*> 0 . DP=4;I16=3,1,0,0,161,6491,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3211 . A <*> 0 . DP=4;I16=3,1,0,0,160,6414,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3212 . T <*> 0 . DP=4;I16=3,1,0,0,163,6643,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 3213 . A <*> 0 . DP=4;I16=3,1,0,0,157,6217,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 3214 . G <*> 0 . DP=4;I16=3,1,0,0,153,5879,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 3215 . G <*> 0 . DP=4;I16=3,1,0,0,144,5382,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3216 . C <*> 0 . DP=4;I16=3,1,0,0,157,6173,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 3217 . C <*> 0 . DP=4;I16=3,1,0,0,140,5000,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 3218 . G <*> 0 . DP=4;I16=3,1,0,0,127,4149,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,112 17 3219 . G <*> 0 . DP=4;I16=3,1,0,0,144,5220,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3220 . G <*> 0 . DP=4;I16=3,1,0,0,144,5214,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3221 . C <*> 0 . DP=4;I16=3,1,0,0,159,6323,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3222 . A <*> 0 . DP=4;I16=3,1,0,0,151,5755,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3223 . C <*> 0 . DP=4;I16=3,1,0,0,150,5660,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3224 . A <*> 0 . DP=4;I16=3,1,0,0,161,6489,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3225 . G <*> 0 . DP=4;I16=3,1,0,0,152,5830,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 3226 . T <*> 0 . DP=4;I16=3,1,0,0,150,5646,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3227 . G <*> 0 . DP=4;I16=3,1,0,0,143,5151,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 3228 . G <*> 0 . DP=4;I16=3,1,0,0,138,4806,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 3229 . C <*> 0 . DP=4;I16=3,1,0,0,143,5121,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3230 . T <*> 0 . DP=4;I16=3,1,0,0,159,6333,0,0,240,14400,0,0,88,2022,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3231 . C <*> 0 . DP=4;I16=3,1,0,0,146,5350,0,0,240,14400,0,0,86,1948,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3232 . A <*> 0 . DP=4;I16=3,1,0,0,149,5721,0,0,240,14400,0,0,84,1878,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3233 . C <*> 0 . DP=4;I16=3,1,0,0,126,3986,0,0,240,14400,0,0,82,1812,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 3234 . G <*> 0 . DP=4;I16=3,1,0,0,112,3510,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQ0F=0 PL 0,12,100 17 3235 . C <*> 0 . DP=4;I16=3,1,0,0,139,4935,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 3236 . C <*> 0 . DP=4;I16=3,1,0,0,153,5897,0,0,240,14400,0,0,76,1638,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 3237 . T <*> 0 . DP=4;I16=3,1,0,0,154,6020,0,0,240,14400,0,0,74,1588,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 3238 . G <*> 0 . DP=4;I16=3,1,0,0,147,5459,0,0,240,14400,0,0,72,1542,0,0;QS=1,0;MQ0F=0 PL 0,12,129 17 3239 . T <*> 0 . DP=4;I16=3,1,0,0,148,5546,0,0,240,14400,0,0,70,1500,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3240 . A <*> 0 . DP=4;I16=3,1,0,0,150,5668,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3241 . A <*> 0 . DP=4;I16=3,1,0,0,163,6655,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 3242 . T <*> 0 . DP=5;I16=4,1,0,0,185,6943,0,0,300,18000,0,0,64,1398,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3243 . C <*> 0 . DP=5;I16=4,1,0,0,187,7013,0,0,300,18000,0,0,63,1373,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 3244 . C <*> 0 . DP=5;I16=4,1,0,0,182,6694,0,0,300,18000,0,0,62,1354,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 3245 . C <*> 0 . DP=4;I16=3,1,0,0,150,5636,0,0,240,14400,0,0,62,1340,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3246 . A <*> 0 . DP=4;I16=3,1,0,0,159,6325,0,0,240,14400,0,0,62,1330,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3247 . G <*> 0 . DP=4;I16=3,1,0,0,151,5747,0,0,240,14400,0,0,62,1324,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3248 . C <*> 0 . DP=4;I16=3,1,0,0,151,5703,0,0,240,14400,0,0,62,1322,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3249 . C <*> 0 . DP=4;I16=3,1,0,0,152,5790,0,0,240,14400,0,0,62,1324,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3250 . C <*> 0 . DP=4;I16=3,1,0,0,156,6126,0,0,240,14400,0,0,62,1330,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 3251 . T <*> 0 . DP=4;I16=3,1,0,0,152,5880,0,0,240,14400,0,0,61,1291,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3252 . T <*> 0 . DP=4;I16=3,1,0,0,141,5161,0,0,240,14400,0,0,60,1258,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3253 . T <*> 0 . DP=4;I16=3,1,0,0,150,5678,0,0,240,14400,0,0,59,1231,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3254 . G <*> 0 . DP=5;I16=3,2,0,0,181,6683,0,0,300,18000,0,0,58,1210,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3255 . G <*> 0 . DP=4;I16=2,2,0,0,133,4817,0,0,240,14400,0,0,59,1195,0,0;QS=1,0;MQ0F=0 PL 0,12,124 17 3256 . G <*> 0 . DP=4;I16=2,2,0,0,155,6093,0,0,240,14400,0,0,60,1186,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 3257 . A <*> 0 . DP=4;I16=2,2,0,0,157,6219,0,0,240,14400,0,0,61,1183,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 3258 . G <*> 0 . DP=4;I16=2,2,0,0,159,6365,0,0,240,14400,0,0,62,1186,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 3259 . G <*> 0 . DP=4;I16=2,2,0,0,151,5753,0,0,240,14400,0,0,63,1195,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3260 . C <*> 0 . DP=4;I16=2,2,0,0,145,5295,0,0,240,14400,0,0,64,1210,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3261 . C <*> 0 . DP=4;I16=2,2,0,0,151,5707,0,0,240,14400,0,0,65,1231,0,0;QS=1,0;MQ0F=0 PL 0,12,138 17 3262 . A <*> 0 . DP=4;I16=2,2,0,0,162,6570,0,0,240,14400,0,0,66,1258,0,0;QS=1,0;MQ0F=0 PL 0,12,148 17 3263 . G <*> 0 . DP=4;I16=2,2,0,0,160,6442,0,0,240,14400,0,0,67,1291,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 3264 . G <*> 0 . DP=4;I16=2,2,0,0,156,6120,0,0,240,14400,0,0,68,1330,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 3265 . G <*> 0 . DP=4;I16=2,2,0,0,148,5530,0,0,240,14400,0,0,69,1375,0,0;QS=1,0;MQ0F=0 PL 0,12,136 17 3266 . T G,<*> 0 . DP=4;I16=1,2,1,0,120,4802,2,4,180,10800,60,3600,61,1345,9,81;QS=0.967742,0.0322581,0;SGB=-0.379885;RPBZ=1.34164;MQBZ=0;MQSBZ=0;BQBZ=-1.34164;SCBZ=1.73205;MQ0F=0 PL 0,5,107,9,110,107 17 3267 . G <*> 0 . DP=4;I16=2,2,0,0,144,5394,0,0,240,14400,0,0,71,1483,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3268 . G <*> 0 . DP=4;I16=2,2,0,0,154,6010,0,0,240,14400,0,0,71,1495,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 3269 . G <*> 0 . DP=4;I16=2,2,0,0,149,5625,0,0,240,14400,0,0,71,1511,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 3270 . T G,<*> 0 . DP=5;I16=2,2,1,0,148,5560,2,4,240,14400,60,3600,65,1457,5,25;QS=0.973684,0.0263158,0;SGB=-0.379885;RPBZ=1.41421;MQBZ=0;MQSBZ=0;BQBZ=-1.41421;SCBZ=2;MQ0F=0 PL 0,8,129,12,132,129 17 3271 . G <*> 0 . DP=4;I16=2,2,0,0,157,6181,0,0,240,14400,0,0,66,1444,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 3272 . G <*> 0 . DP=4;I16=2,2,0,0,153,5881,0,0,240,14400,0,0,67,1437,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3273 . A <*> 0 . DP=4;I16=2,2,0,0,161,6485,0,0,240,14400,0,0,68,1436,0,0;QS=1,0;MQ0F=0 PL 0,12,147 17 3274 . T <*> 0 . DP=4;I16=2,2,0,0,163,6653,0,0,240,14400,0,0,69,1441,0,0;QS=1,0;MQ0F=0 PL 0,12,149 17 3275 . C <*> 0 . DP=4;I16=2,2,0,0,152,5808,0,0,240,14400,0,0,70,1452,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3276 . A <*> 0 . DP=4;I16=2,2,0,0,154,5948,0,0,240,14400,0,0,71,1469,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3277 . C <*> 0 . DP=4;I16=2,2,0,0,159,6333,0,0,240,14400,0,0,72,1492,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 3278 . T <*> 0 . DP=4;I16=2,2,0,0,167,6993,0,0,240,14400,0,0,73,1521,0,0;QS=1,0;MQ0F=0 PL 0,12,153 17 3279 . T <*> 0 . DP=4;I16=2,2,0,0,164,6728,0,0,240,14400,0,0,74,1556,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 3280 . G <*> 0 . DP=4;I16=2,2,0,0,160,6466,0,0,240,14400,0,0,74,1546,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 3281 . A <*> 0 . DP=4;I16=2,2,0,0,172,7410,0,0,240,14400,0,0,74,1540,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3282 . G <*> 0 . DP=4;I16=2,2,0,0,164,6738,0,0,240,14400,0,0,74,1538,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 3283 . G <*> 0 . DP=4;I16=2,2,0,0,160,6406,0,0,240,14400,0,0,74,1540,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 3284 . T <*> 0 . DP=4;I16=2,2,0,0,160,6420,0,0,240,14400,0,0,74,1546,0,0;QS=1,0;MQ0F=0 PL 0,12,146 17 3285 . C <*> 0 . DP=4;I16=2,2,0,0,157,6167,0,0,240,14400,0,0,74,1556,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 3286 . A <*> 0 . DP=4;I16=2,2,0,0,167,6985,0,0,240,14400,0,0,74,1570,0,0;QS=1,0;MQ0F=0 PL 0,12,153 17 3287 . G <*> 0 . DP=4;I16=2,2,0,0,164,6750,0,0,240,14400,0,0,74,1588,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 3288 . G <*> 0 . DP=5;I16=3,2,0,0,188,7194,0,0,300,18000,0,0,74,1610,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3289 . A <*> 0 . DP=5;I16=3,2,0,0,205,8443,0,0,300,18000,0,0,75,1637,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3290 . G <*> 0 . DP=5;I16=3,2,0,0,193,7487,0,0,300,18000,0,0,76,1670,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 3291 . T <*> 0 . DP=5;I16=3,2,0,0,193,7485,0,0,300,18000,0,0,77,1709,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 3292 . T <*> 0 . DP=5;I16=3,2,0,0,189,7171,0,0,300,18000,0,0,78,1754,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3293 . C <*> 0 . DP=5;I16=3,2,0,0,196,7710,0,0,300,18000,0,0,79,1805,0,0;QS=1,0;MQ0F=0 PL 0,15,170 17 3294 . A <*> 0 . DP=5;I16=3,2,0,0,189,7207,0,0,300,18000,0,0,80,1862,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3295 . A <*> 0 . DP=4;I16=3,1,0,0,162,6602,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQ0F=0 PL 0,12,143 17 3296 . G <*> 0 . DP=4;I16=3,1,0,0,159,6345,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3297 . A <*> 0 . DP=4;I16=3,1,0,0,159,6369,0,0,240,14400,0,0,84,1956,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3298 . C <*> 0 . DP=4;I16=3,1,0,0,153,5941,0,0,240,14400,0,0,85,1975,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3299 . C <*> 0 . DP=4;I16=3,1,0,0,160,6414,0,0,240,14400,0,0,86,1996,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3300 . A <*> 0 . DP=4;I16=3,1,0,0,164,6742,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQ0F=0 PL 0,12,144 17 3301 . G <*> 0 . DP=4;I16=3,1,0,0,161,6507,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,12,141 17 3302 . C <*> 0 . DP=5;I16=4,1,0,0,189,7235,0,0,300,18000,0,0,89,2071,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 3303 . C <*> 0 . DP=5;I16=4,1,0,0,187,7051,0,0,300,18000,0,0,91,2101,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 3304 . T <*> 0 . DP=5;I16=4,1,0,0,206,8500,0,0,300,18000,0,0,93,2135,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3305 . G <*> 0 . DP=5;I16=4,1,0,0,186,6948,0,0,300,18000,0,0,95,2173,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 3306 . G <*> 0 . DP=5;I16=4,1,0,0,184,6832,0,0,300,18000,0,0,97,2215,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 3307 . C <*> 0 . DP=5;I16=4,1,0,0,188,7098,0,0,300,18000,0,0,99,2261,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 3308 . C <*> 0 . DP=5;I16=4,1,0,0,184,6890,0,0,300,18000,0,0,101,2311,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 3309 . A <*> 0 . DP=5;I16=4,1,0,0,199,7939,0,0,300,18000,0,0,103,2365,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3310 . A <*> 0 . DP=5;I16=4,1,0,0,201,8123,0,0,300,18000,0,0,105,2423,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3311 . C <*> 0 . DP=5;I16=4,1,0,0,191,7391,0,0,300,18000,0,0,107,2485,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3312 . A <*> 0 . DP=5;I16=4,1,0,0,196,7738,0,0,300,18000,0,0,109,2551,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 3313 . T <*> 0 . DP=5;I16=4,1,0,0,198,7856,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3314 . G <*> 0 . DP=5;I16=4,1,0,0,197,7831,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3315 . G <*> 0 . DP=5;I16=4,1,0,0,189,7205,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 3316 . T G,<*> 0 . DP=5;I16=3,1,1,0,139,4903,4,16,240,14400,60,3600,89,2071,25,625;QS=0.972028,0.027972,0;SGB=-0.379885;RPBZ=0;MQBZ=0;MQSBZ=0;BQBZ=-1.45095;SCBZ=0;MQ0F=0 PL 0,8,116,12,119,116 17 3317 . G <*> 0 . DP=6;I16=4,2,0,0,203,7051,0,0,360,21600,0,0,115,2725,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 3318 . A <*> 0 . DP=6;I16=4,2,0,0,225,8557,0,0,360,21600,0,0,116,2708,0,0;QS=1,0;MQ0F=0 PL 0,18,185 17 3319 . A <*> 0 . DP=6;I16=4,2,0,0,230,9112,0,0,360,21600,0,0,117,2697,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3320 . A <*> 0 . DP=6;I16=4,2,0,0,219,8503,0,0,360,21600,0,0,118,2692,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 3321 . C <*> 0 . DP=6;I16=4,2,0,0,228,8702,0,0,360,21600,0,0,119,2693,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3322 . C <*> 0 . DP=6;I16=4,2,0,0,242,9784,0,0,360,21600,0,0,120,2700,0,0;QS=1,0;MQ0F=0 PL 0,18,198 17 3323 . C <*> 0 . DP=6;I16=4,2,0,0,246,10108,0,0,360,21600,0,0,121,2713,0,0;QS=1,0;MQ0F=0 PL 0,18,201 17 3324 . C <*> 0 . DP=6;I16=4,2,0,0,227,8665,0,0,360,21600,0,0,122,2732,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3325 . G <*> 0 . DP=6;I16=4,2,0,0,200,6766,0,0,360,21600,0,0,123,2757,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 3326 . T <*> 0 . DP=6;I16=4,2,0,0,228,8706,0,0,360,21600,0,0,124,2788,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3327 . C <*> 0 . DP=6;I16=4,2,0,0,233,9073,0,0,360,21600,0,0,125,2825,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 3328 . T <*> 0 . DP=7;I16=5,2,0,0,277,11019,0,0,420,25200,0,0,125,2817,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 3329 . A <*> 0 . DP=7;I16=5,2,0,0,273,10661,0,0,420,25200,0,0,126,2814,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 3330 . C <*> 0 . DP=7;I16=5,2,0,0,265,10087,0,0,420,25200,0,0,126,2768,0,0;QS=1,0;MQ0F=0 PL 0,21,203 17 3331 . T <*> 0 . DP=7;I16=5,2,0,0,289,11969,0,0,420,25200,0,0,126,2730,0,0;QS=1,0;MQ0F=0 PL 0,21,224 17 3332 . A <*> 0 . DP=7;I16=5,2,0,0,275,10819,0,0,420,25200,0,0,126,2700,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 3333 . A <*> 0 . DP=8;I16=5,3,0,0,326,13370,0,0,480,28800,0,0,126,2678,0,0;QS=1,0;MQ0F=0 PL 0,24,247 17 3334 . A <*> 0 . DP=8;I16=5,3,0,0,326,13372,0,0,480,28800,0,0,127,2665,0,0;QS=1,0;MQ0F=0 PL 0,24,247 17 3335 . A <*> 0 . DP=8;I16=5,3,0,0,316,12884,0,0,480,28800,0,0,128,2662,0,0;QS=1,0;MQ0F=0 PL 0,24,239 17 3336 . A <*> 0 . DP=8;I16=5,3,0,0,312,12240,0,0,480,28800,0,0,129,2669,0,0;QS=1,0;MQ0F=0 PL 0,24,236 17 3337 . T <*> 0 . DP=8;I16=5,3,0,0,296,11006,0,0,480,28800,0,0,130,2686,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 3338 . A <*> 0 . DP=8;I16=5,3,0,0,285,10199,0,0,480,28800,0,0,131,2713,0,0;QS=1,0;MQ0F=0 PL 0,24,214 17 3339 . C <*> 0 . DP=8;I16=5,3,0,0,308,11888,0,0,480,28800,0,0,132,2750,0,0;QS=1,0;MQ0F=0 PL 0,24,232 17 3340 . A <*> 0 . DP=8;I16=5,3,0,0,317,12575,0,0,480,28800,0,0,133,2797,0,0;QS=1,0;MQ0F=0 PL 0,24,238 17 3341 . A <*> 0 . DP=8;I16=5,3,0,0,320,12862,0,0,480,28800,0,0,134,2854,0,0;QS=1,0;MQ0F=0 PL 0,24,242 17 3342 . A <*> 0 . DP=8;I16=5,3,0,0,323,13105,0,0,480,28800,0,0,135,2921,0,0;QS=1,0;MQ0F=0 PL 0,24,245 17 3343 . A <*> 0 . DP=7;I16=4,3,0,0,288,11884,0,0,420,25200,0,0,136,2946,0,0;QS=1,0;MQ0F=0 PL 0,21,231 17 3344 . A <*> 0 . DP=7;I16=4,3,0,0,283,11479,0,0,420,25200,0,0,137,2977,0,0;QS=1,0;MQ0F=0 PL 0,21,226 17 3345 . T <*> 0 . DP=7;I16=4,3,0,0,276,10926,0,0,420,25200,0,0,138,3014,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 3346 . T <*> 0 . DP=7;I16=4,3,0,0,278,11054,0,0,420,25200,0,0,138,3008,0,0;QS=1,0;MQ0F=0 PL 0,21,221 17 3347 . A <*> 0 . DP=7;I16=4,3,0,0,284,11564,0,0,420,25200,0,0,138,3010,0,0;QS=1,0;MQ0F=0 PL 0,21,227 17 3348 . G <*> 0 . DP=7;I16=4,3,0,0,275,10841,0,0,420,25200,0,0,138,3020,0,0;QS=1,0;MQ0F=0 PL 0,21,219 17 3349 . C <*> 0 . DP=7;I16=4,3,0,0,257,9491,0,0,420,25200,0,0,138,3038,0,0;QS=1,0;MQ0F=0 PL 0,21,205 17 3350 . C <*> 0 . DP=7;I16=4,3,0,0,273,10843,0,0,420,25200,0,0,138,3064,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 3351 . T <*> 0 . DP=7;I16=4,3,0,0,286,11716,0,0,420,25200,0,0,138,3098,0,0;QS=1,0;MQ0F=0 PL 0,21,228 17 3352 . G <*> 0 . DP=7;I16=4,3,0,0,269,10375,0,0,420,25200,0,0,138,3140,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 3353 . G <*> 0 . DP=7;I16=4,3,0,0,268,10312,0,0,420,25200,0,0,138,3190,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 3354 . C <*> 0 . DP=7;I16=4,3,0,0,260,9824,0,0,420,25200,0,0,137,3197,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3355 . G <*> 0 . DP=6;I16=4,2,0,0,202,6932,0,0,360,21600,0,0,137,3209,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 3356 . T <*> 0 . DP=6;I16=4,2,0,0,241,9683,0,0,360,21600,0,0,137,3225,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3357 . G <*> 0 . DP=6;I16=4,2,0,0,235,9245,0,0,360,21600,0,0,137,3245,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3358 . G <*> 0 . DP=6;I16=4,2,0,0,228,8744,0,0,360,21600,0,0,137,3269,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3359 . T G,<*> 0 . DP=6;I16=3,2,1,0,185,6969,2,4,300,18000,60,3600,125,3125,11,121;QS=0.978836,0.021164,0;SGB=-0.379885;RPBZ=1.46385;MQBZ=0;MQSBZ=0;BQBZ=-1.46385;SCBZ=0;MQ0F=0 PL 0,10,155,15,158,155 17 3360 . G <*> 0 . DP=6;I16=4,2,0,0,211,7669,0,0,360,21600,0,0,135,3225,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 3361 . G <*> 0 . DP=6;I16=4,2,0,0,211,7655,0,0,360,21600,0,0,134,3206,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 3362 . C <*> 0 . DP=6;I16=4,2,0,0,210,7526,0,0,360,21600,0,0,133,3189,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 3363 . G <*> 0 . DP=6;I16=4,2,0,0,195,6625,0,0,360,21600,0,0,132,3174,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 3364 . C <*> 0 . DP=6;I16=4,2,0,0,237,9403,0,0,360,21600,0,0,130,3112,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3365 . A <*> 0 . DP=6;I16=4,2,0,0,232,9030,0,0,360,21600,0,0,128,3054,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 3366 . T <*> 0 . DP=6;I16=4,2,0,0,212,7962,0,0,360,21600,0,0,126,3000,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 3367 . G <*> 0 . DP=6;I16=4,2,0,0,205,7173,0,0,360,21600,0,0,124,2950,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 3368 . C <*> 0 . DP=6;I16=4,2,0,0,232,9012,0,0,360,21600,0,0,122,2904,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3369 . C <*> 0 . DP=6;I16=4,2,0,0,234,9220,0,0,360,21600,0,0,120,2862,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3370 . T <*> 0 . DP=6;I16=4,2,0,0,207,8447,0,0,360,21600,0,0,118,2824,0,0;QS=1,0;MQ0F=0 PL 0,18,177 17 3371 . G <*> 0 . DP=5;I16=3,2,0,0,195,7619,0,0,300,18000,0,0,117,2789,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3372 . T <*> 0 . DP=5;I16=3,2,0,0,192,7422,0,0,300,18000,0,0,116,2756,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3373 . A <*> 0 . DP=5;I16=3,2,0,0,201,8089,0,0,300,18000,0,0,115,2725,0,0;QS=1,0;MQ0F=0 PL 0,15,174 17 3374 . A <*> 0 . DP=5;I16=3,2,0,0,188,7246,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3375 . T <*> 0 . DP=5;I16=3,2,0,0,198,7866,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 3376 . C <*> 0 . DP=5;I16=3,2,0,0,199,7999,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 3377 . C <*> 0 . DP=5;I16=3,2,0,0,200,8008,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 3378 . C <*> 0 . DP=5;I16=3,2,0,0,198,7862,0,0,300,18000,0,0,109,2551,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 3379 . A <*> 0 . DP=5;I16=3,2,0,0,195,7735,0,0,300,18000,0,0,107,2485,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3380 . G <*> 0 . DP=5;I16=3,2,0,0,206,8502,0,0,300,18000,0,0,105,2423,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3381 . C <*> 0 . DP=5;I16=3,2,0,0,206,8502,0,0,300,18000,0,0,103,2365,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3382 . T <*> 0 . DP=5;I16=3,2,0,0,212,9010,0,0,300,18000,0,0,101,2311,0,0;QS=1,0;MQ0F=0 PL 0,15,184 17 3383 . A <*> 0 . DP=5;I16=3,2,0,0,192,7396,0,0,300,18000,0,0,99,2261,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3384 . C <*> 0 . DP=6;I16=4,2,0,0,228,8720,0,0,360,21600,0,0,97,2215,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3385 . T <*> 0 . DP=6;I16=4,2,0,0,238,9646,0,0,360,21600,0,0,96,2174,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3386 . T <*> 0 . DP=6;I16=4,2,0,0,230,8866,0,0,360,21600,0,0,95,2139,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3387 . G <*> 0 . DP=7;I16=4,3,0,0,272,10616,0,0,420,25200,0,0,94,2110,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 3388 . G <*> 0 . DP=7;I16=4,3,0,0,262,9852,0,0,420,25200,0,0,94,2088,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3389 . G <*> 0 . DP=7;I16=3,4,0,0,260,9726,0,0,420,25200,0,0,95,2073,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 3390 . A <*> 0 . DP=7;I16=3,4,0,0,246,8932,0,0,420,25200,0,0,97,2065,0,0;QS=1,0;MQ0F=0 PL 0,21,198 17 3391 . A <*> 0 . DP=7;I16=3,4,0,0,281,11333,0,0,420,25200,0,0,99,2065,0,0;QS=1,0;MQ0F=0 PL 0,21,224 17 3392 . G <*> 0 . DP=7;I16=3,4,0,0,271,10519,0,0,420,25200,0,0,101,2073,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 3393 . C <*> 0 . DP=7;I16=3,4,0,0,268,10320,0,0,420,25200,0,0,102,2040,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 3394 . T <*> 0 . DP=7;I16=3,4,0,0,278,11116,0,0,420,25200,0,0,103,2017,0,0;QS=1,0;MQ0F=0 PL 0,21,222 17 3395 . G <*> 0 . DP=7;I16=3,4,0,0,278,11050,0,0,420,25200,0,0,104,2004,0,0;QS=1,0;MQ0F=0 PL 0,21,222 17 3396 . A <*> 0 . DP=7;I16=3,4,0,0,290,12038,0,0,420,25200,0,0,105,2001,0,0;QS=1,0;MQ0F=0 PL 0,21,232 17 3397 . G <*> 0 . DP=7;I16=3,4,0,0,272,10616,0,0,420,25200,0,0,106,2008,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 3398 . G <*> 0 . DP=7;I16=3,4,0,0,271,10501,0,0,420,25200,0,0,107,2025,0,0;QS=1,0;MQ0F=0 PL 0,21,215 17 3399 . G <*> 0 . DP=7;I16=3,4,0,0,269,10353,0,0,420,25200,0,0,108,2052,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 3400 . A <*> 0 . DP=7;I16=3,4,0,0,266,10162,0,0,420,25200,0,0,109,2089,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 3401 . T <*> 0 . DP=7;I16=3,4,0,0,270,10470,0,0,420,25200,0,0,110,2136,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 3402 . G <*> 0 . DP=7;I16=3,4,0,0,266,10140,0,0,420,25200,0,0,111,2193,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 3403 . A <*> 0 . DP=6;I16=2,4,0,0,250,10446,0,0,360,21600,0,0,113,2259,0,0;QS=1,0;MQ0F=0 PL 0,18,205 17 3404 . G <*> 0 . DP=6;I16=2,4,0,0,227,8687,0,0,360,21600,0,0,114,2284,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3405 . A <*> 0 . DP=6;I16=2,4,0,0,217,8007,0,0,360,21600,0,0,115,2319,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3406 . A <*> 0 . DP=6;I16=2,4,0,0,225,8587,0,0,360,21600,0,0,116,2364,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3407 . C <*> 0 . DP=6;I16=2,4,0,0,223,8377,0,0,360,21600,0,0,117,2419,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 3408 . T <*> 0 . DP=6;I16=2,4,0,0,231,8963,0,0,360,21600,0,0,118,2484,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3409 . G <*> 0 . DP=6;I16=2,4,0,0,236,9304,0,0,360,21600,0,0,118,2510,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3410 . C <*> 0 . DP=6;I16=2,4,0,0,213,7767,0,0,360,21600,0,0,117,2497,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 3411 . T <*> 0 . DP=6;I16=2,4,0,0,240,9648,0,0,360,21600,0,0,116,2494,0,0;QS=1,0;MQ0F=0 PL 0,18,196 17 3412 . T <*> 0 . DP=6;I16=2,4,0,0,231,8909,0,0,360,21600,0,0,115,2501,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3413 . G <*> 0 . DP=6;I16=2,4,0,0,226,8538,0,0,360,21600,0,0,113,2467,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 3414 . A <*> 0 . DP=6;I16=2,4,0,0,200,6886,0,0,360,21600,0,0,111,2441,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 3415 . A <*> 0 . DP=7;I16=2,5,0,0,221,7827,0,0,420,25200,0,0,108,2372,0,0;QS=1,0;MQ0F=0 PL 0,21,179 17 3416 . C <*> 0 . DP=7;I16=2,5,0,0,244,8750,0,0,420,25200,0,0,106,2310,0,0;QS=1,0;MQ0F=0 PL 0,21,191 17 3417 . C <*> 0 . DP=7;I16=2,5,0,0,246,8910,0,0,420,25200,0,0,104,2256,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 3418 . T <*> 0 . DP=6;I16=2,4,0,0,210,8264,0,0,360,21600,0,0,103,2209,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3419 . G <*> 0 . DP=6;I16=2,4,0,0,233,9083,0,0,360,21600,0,0,102,2168,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 3420 . G <*> 0 . DP=6;I16=2,4,0,0,229,8827,0,0,360,21600,0,0,101,2133,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3421 . G <*> 0 . DP=6;I16=2,4,0,0,233,9121,0,0,360,21600,0,0,100,2104,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 3422 . A <*> 0 . DP=6;I16=2,4,0,0,223,8877,0,0,360,21600,0,0,99,2081,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3423 . G <*> 0 . DP=6;I16=2,4,0,0,218,8380,0,0,360,21600,0,0,98,2064,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 3424 . G <*> 0 . DP=6;I16=2,4,0,0,198,7630,0,0,360,21600,0,0,97,2053,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 3425 . C <*> 0 . DP=6;I16=2,4,0,0,225,8575,0,0,360,21600,0,0,96,2048,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3426 . A <*> 0 . DP=6;I16=2,4,0,0,246,10136,0,0,360,21600,0,0,95,2049,0,0;QS=1,0;MQ0F=0 PL 0,18,202 17 3427 . G <*> 0 . DP=6;I16=2,4,0,0,222,8438,0,0,360,21600,0,0,94,2056,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 3428 . A <*> 0 . DP=6;I16=2,4,0,0,214,8092,0,0,360,21600,0,0,93,2069,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3429 . C <*> 0 . DP=5;I16=1,4,0,0,147,4699,0,0,300,18000,0,0,93,2087,0,0;QS=1,0;MQ0F=0 PL 0,15,124 17 3430 . G <*> 0 . DP=5;I16=1,4,0,0,172,6190,0,0,300,18000,0,0,93,2109,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 3431 . T <*> 0 . DP=5;I16=1,4,0,0,202,8244,0,0,300,18000,0,0,93,2135,0,0;QS=1,0;MQ0F=0 PL 0,15,166 17 3432 . T <*> 0 . DP=5;I16=1,4,0,0,201,8115,0,0,300,18000,0,0,93,2165,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3433 . G <*> 0 . DP=5;I16=1,4,0,0,199,8033,0,0,300,18000,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3434 . C <*> 0 . DP=4;I16=1,3,0,0,155,6027,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 3435 . A <*> 0 . DP=4;I16=1,3,0,0,171,7323,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,151 17 3436 . G <*> 0 . DP=4;I16=1,3,0,0,149,5725,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3437 . T <*> 0 . DP=4;I16=1,3,0,0,149,5673,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3438 . G <*> 0 . DP=4;I16=1,3,0,0,159,6389,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,140 17 3439 . A <*> 0 . DP=4;I16=1,3,0,0,146,5892,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3440 . G <*> 0 . DP=4;I16=1,3,0,0,147,5655,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3441 . C <*> 0 . DP=4;I16=1,3,0,0,132,5064,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,121 17 3442 . T <*> 0 . DP=4;I16=1,3,0,0,141,5577,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3443 . G <*> 0 . DP=4;I16=1,3,0,0,155,6075,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 3444 . A <*> 0 . DP=4;I16=1,3,0,0,144,5778,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3445 . G <*> 0 . DP=4;I16=1,3,0,0,148,5714,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3446 . A <*> 0 . DP=4;I16=1,3,0,0,146,5580,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3447 . T <*> 0 . DP=4;I16=1,3,0,0,156,6134,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,137 17 3448 . C <*> 0 . DP=4;I16=1,3,0,0,145,5353,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3449 . A <*> 0 . DP=4;I16=1,3,0,0,133,4665,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,119 17 3450 . C <*> 0 . DP=4;I16=1,3,0,0,119,3693,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,106 17 3451 . G <*> 0 . DP=4;I16=1,3,0,0,140,4986,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,123 17 3452 . C <*> 0 . DP=4;I16=1,3,0,0,145,5355,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3453 . C <*> 0 . DP=4;I16=1,3,0,0,141,5043,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 3454 . A <*> 0 . DP=4;I16=1,3,0,0,144,5350,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,128 17 3455 . C <*> 0 . DP=4;I16=1,3,0,0,143,5239,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,127 17 3456 . T <*> 0 . DP=4;I16=1,3,0,0,152,5886,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3457 . G <*> 0 . DP=4;I16=1,3,0,0,121,4389,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,110 17 3458 . C <*> 0 . DP=4;I16=1,3,0,0,141,5087,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,125 17 3459 . A <*> 0 . DP=4;I16=1,3,0,0,129,4565,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,116 17 3460 . C <*> 0 . DP=4;I16=1,3,0,0,147,5523,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3461 . T <*> 0 . DP=4;I16=1,3,0,0,149,5861,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3462 . C <*> 0 . DP=4;I16=1,3,0,0,148,5506,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,130 17 3463 . C <*> 0 . DP=4;I16=1,3,0,0,150,5654,0,0,240,14400,0,0,95,2267,0,0;QS=1,0;MQ0F=0 PL 0,12,132 17 3464 . A <*> 0 . DP=4;I16=1,3,0,0,162,6566,0,0,240,14400,0,0,93,2179,0,0;QS=1,0;MQ0F=0 PL 0,12,142 17 3465 . G <*> 0 . DP=4;I16=1,3,0,0,152,5846,0,0,240,14400,0,0,90,2046,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3466 . C <*> 0 . DP=5;I16=2,3,0,0,167,5901,0,0,269,15241,0,0,87,1919,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 3467 . C <*> 0 . DP=5;I16=2,3,0,0,176,6432,0,0,269,15241,0,0,85,1799,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 3468 . T <*> 0 . DP=5;I16=2,3,0,0,188,7216,0,0,269,15241,0,0,83,1687,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3469 . G <*> 0 . DP=5;I16=2,3,0,0,187,7095,0,0,269,15241,0,0,81,1583,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 3470 . G <*> 0 . DP=5;I16=2,3,0,0,189,7187,0,0,269,15241,0,0,79,1487,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3471 . G <*> 0 . DP=5;I16=2,3,0,0,176,6254,0,0,269,15241,0,0,77,1399,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 3472 . C <*> 0 . DP=5;I16=2,3,0,0,154,5146,0,0,269,15241,0,0,75,1319,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 3473 . A <*> 0 . DP=5;I16=2,3,0,0,179,6483,0,0,269,15241,0,0,73,1247,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 3474 . A <*> 0 . DP=5;I16=2,3,0,0,182,6656,0,0,269,15241,0,0,71,1183,0,0;QS=1,0;MQ0F=0 PL 0,15,155 17 3475 . C <*> 0 . DP=5;I16=2,3,0,0,162,5582,0,0,269,15241,0,0,69,1127,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 3476 . A <*> 0 . DP=5;I16=2,3,0,0,175,6435,0,0,269,15241,0,0,67,1079,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 3477 . G <*> 0 . DP=5;I16=2,3,0,0,185,6909,0,0,269,15241,0,0,65,1039,0,0;QS=1,0;MQ0F=0 PL 0,15,153 17 3478 . A <*> 0 . DP=6;I16=2,4,0,0,241,9715,0,0,329,18841,0,0,63,1007,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3479 . G <*> 0 . DP=6;I16=2,4,0,0,195,6461,0,0,329,18841,0,0,62,984,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 3480 . T <*> 0 . DP=6;I16=2,4,0,0,185,6329,0,0,329,18841,0,0,61,971,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 3481 . A <*> 0 . DP=6;I16=2,4,0,0,193,6747,0,0,329,18841,0,0,60,968,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 3482 . A <*> 0 . DP=6;I16=2,4,0,0,221,8411,0,0,329,18841,0,0,59,975,0,0;QS=1,0;MQ0F=0 PL 0,18,182 17 3483 . G <*> 0 . DP=6;I16=2,4,0,0,192,6394,0,0,329,18841,0,0,58,992,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 3484 . A <*> 0 . DP=6;I16=2,4,0,0,167,5655,0,0,329,18841,0,0,57,1019,0,0;QS=1,0;MQ0F=0 PL 0,18,141 17 3485 . C <*> 0 . DP=5;I16=1,4,0,0,150,4886,0,0,269,15241,0,0,57,1055,0,0;QS=1,0;MQ0F=0 PL 0,15,120 17 3486 . T <*> 0 . DP=5;I16=1,4,0,0,153,4891,0,0,269,15241,0,0,57,1099,0,0;QS=1,0;MQ0F=0 PL 0,15,128 17 3487 . C <*> 0 . DP=5;I16=1,4,0,0,128,3714,0,0,269,15241,0,0,57,1151,0,0;QS=1,0;MQ0F=0 PL 0,15,104 17 3488 . T <*> 0 . DP=4;I16=1,3,0,0,110,3222,0,0,209,11641,0,0,58,1210,0,0;QS=1,0;MQ0F=0 PL 0,12,98 17 3489 . G <*> 0 . DP=4;I16=1,3,0,0,85,1953,0,0,209,11641,0,0,59,1275,0,0;QS=1,0;MQ0F=0 PL 0,12,75 17 3490 . T <*> 0 . DP=3;I16=1,2,0,0,93,2945,0,0,149,8041,0,0,61,1345,0,0;QS=1,0;MQ0F=0 PL 0,9,85 17 3491 . C <*> 0 . DP=3;I16=1,2,0,0,83,2325,0,0,149,8041,0,0,62,1370,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 3492 . T <*> 0 . DP=3;I16=1,2,0,0,110,4086,0,0,149,8041,0,0,62,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 3493 . C <*> 0 . DP=3;I16=1,2,0,0,84,2510,0,0,149,8041,0,0,62,1334,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 3494 . A <*> 0 . DP=5;I16=1,4,0,0,149,5447,0,0,269,15241,0,0,87,1947,0,0;QS=1,0;MQ0F=0 PL 0,15,122 17 3495 . A <*> 0 . DP=5;I16=1,4,0,0,155,5055,0,0,269,15241,0,0,88,1940,0,0;QS=1,0;MQ0F=0 PL 0,15,129 17 3496 . A <*> 0 . DP=5;I16=1,4,0,0,178,6412,0,0,269,15241,0,0,89,1939,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 3497 . A <*> 0 . DP=6;I16=1,5,0,0,222,8256,0,0,329,18841,0,0,90,1944,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 3498 . A <*> 0 . DP=6;I16=1,5,0,0,181,6121,0,0,329,18841,0,0,92,1956,0,0;QS=1,0;MQ0F=0 PL 0,18,134 17 3499 . A <*> 0 . DP=6;I16=1,5,0,0,205,7259,0,0,329,18841,0,0,94,1976,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 3500 . A <*> 0 . DP=6;I16=1,5,0,0,213,7715,0,0,329,18841,0,0,96,2004,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 3501 . A <*> 0 . DP=6;I16=1,5,0,0,215,7847,0,0,329,18841,0,0,98,2040,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 3502 . A <*> 0 . DP=6;I16=1,5,0,0,234,9146,0,0,329,18841,0,0,100,2084,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 3503 . A <*> 0 . DP=6;I16=1,5,0,0,222,8318,0,0,329,18841,0,0,102,2136,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 3504 . A <*> 0 . DP=6;I16=1,5,0,0,206,7402,0,0,329,18841,0,0,103,2145,0,0;QS=1,0;MQ0F=0 PL 0,18,156 17 3505 . A <*> 0 . DP=6;I16=1,5,0,0,217,8043,0,0,329,18841,0,0,104,2160,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 3506 . A <*> 0 . DP=6;I16=1,5,0,0,221,8287,0,0,329,18841,0,0,105,2181,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 3507 . T <*> 0 . DP=6;I16=1,5,0,0,201,7061,0,0,329,18841,0,0,106,2208,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 3508 . C A,<*> 0 . DP=6;I16=0,5,1,0,164,5506,2,4,300,18000,29,841,82,1616,25,625;QS=0.97619,0.0238095,0;SGB=-0.379885;RPBZ=1.46385;MQBZ=-2.23607;MQSBZ=2.23607;BQBZ=-1.46385;SCBZ=1.73205;MQ0F=0 PL 0,10,113,15,116,114 17 3509 . A <*> 0 . DP=5;I16=0,5,0,0,171,6123,0,0,300,18000,0,0,83,1655,0,0;QS=1,0;MQ0F=0 PL 0,15,125 17 3510 . C <*> 0 . DP=5;I16=0,5,0,0,163,5573,0,0,300,18000,0,0,84,1700,0,0;QS=1,0;MQ0F=0 PL 0,15,119 17 3511 . A <*> 0 . DP=5;I16=0,5,0,0,153,5207,0,0,300,18000,0,0,85,1751,0,0;QS=1,0;MQ0F=0 PL 0,15,115 17 3512 . C <*> 0 . DP=5;I16=0,5,0,0,184,6822,0,0,300,18000,0,0,86,1808,0,0;QS=1,0;MQ0F=0 PL 0,15,131 17 3513 . C <*> 0 . DP=5;I16=0,5,0,0,193,7455,0,0,300,18000,0,0,87,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 3514 . A <*> 0 . DP=5;I16=0,5,0,0,187,7015,0,0,300,18000,0,0,88,1940,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 3515 . T <*> 0 . DP=5;I16=0,5,0,0,176,6310,0,0,300,18000,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,15,127 17 3516 . T <*> 0 . DP=5;I16=1,4,0,0,167,5847,0,0,300,18000,0,0,91,2095,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 3517 . T <*> 0 . DP=5;I16=1,4,0,0,200,8022,0,0,300,18000,0,0,94,2180,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 3518 . T <*> 0 . DP=5;I16=1,4,0,0,178,6582,0,0,300,18000,0,0,97,2271,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 3519 . G <*> 0 . DP=5;I16=1,4,0,0,186,7038,0,0,300,18000,0,0,100,2368,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 3520 . G <*> 0 . DP=5;I16=1,4,0,0,182,6838,0,0,300,18000,0,0,102,2420,0,0;QS=1,0;MQ0F=0 PL 0,15,151 17 3521 . C <*> 0 . DP=5;I16=1,4,0,0,172,6182,0,0,300,18000,0,0,104,2476,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 3522 . T <*> 0 . DP=5;I16=1,4,0,0,191,7423,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3523 . T <*> 0 . DP=5;I16=1,4,0,0,175,6319,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,145 17 3524 . C <*> 0 . DP=5;I16=1,4,0,0,186,6934,0,0,300,18000,0,0,107,2515,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3525 . A <*> 0 . DP=5;I16=1,4,0,0,202,8238,0,0,300,18000,0,0,107,2485,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3526 . G <*> 0 . DP=5;I16=1,4,0,0,178,6462,0,0,300,18000,0,0,107,2459,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 3527 . A <*> 0 . DP=5;I16=1,4,0,0,194,7536,0,0,300,18000,0,0,107,2437,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3528 . T <*> 0 . DP=5;I16=1,4,0,0,188,7070,0,0,300,18000,0,0,107,2419,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3529 . T <*> 0 . DP=5;I16=1,4,0,0,189,7189,0,0,300,18000,0,0,107,2405,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 3530 . G <*> 0 . DP=6;I16=2,4,0,0,214,7662,0,0,360,21600,0,0,107,2395,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 3531 . C <*> 0 . DP=6;I16=2,4,0,0,214,7676,0,0,360,21600,0,0,108,2390,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 3532 . A <*> 0 . DP=6;I16=2,4,0,0,226,8542,0,0,360,21600,0,0,109,2391,0,0;QS=1,0;MQ0F=0 PL 0,18,184 17 3533 . T <*> 0 . DP=6;I16=2,4,0,0,215,7781,0,0,360,21600,0,0,110,2398,0,0;QS=1,0;MQ0F=0 PL 0,18,176 17 3534 . A <*> 0 . DP=6;I16=2,4,0,0,213,7633,0,0,360,21600,0,0,111,2411,0,0;QS=1,0;MQ0F=0 PL 0,18,175 17 3535 . T <*> 0 . DP=6;I16=2,4,0,0,200,6770,0,0,360,21600,0,0,112,2430,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 3536 . C <*> 0 . DP=6;I16=2,4,0,0,221,8183,0,0,360,21600,0,0,113,2455,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 3537 . C <*> 0 . DP=6;I16=2,4,0,0,227,8613,0,0,360,21600,0,0,114,2486,0,0;QS=1,0;MQ0F=0 PL 0,18,185 17 3538 . T <*> 0 . DP=6;I16=2,4,0,0,223,8539,0,0,360,21600,0,0,115,2523,0,0;QS=1,0;MQ0F=0 PL 0,18,185 17 3539 . C <*> 0 . DP=6;I16=2,4,0,0,207,7591,0,0,360,21600,0,0,116,2566,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 3540 . C <*> 0 . DP=6;I16=2,4,0,0,207,7427,0,0,360,21600,0,0,117,2615,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 3541 . T <*> 0 . DP=6;I16=2,4,0,0,226,8816,0,0,360,21600,0,0,118,2670,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3542 . G <*> 0 . DP=6;I16=2,4,0,0,206,7510,0,0,360,21600,0,0,118,2680,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 3543 . C <*> 0 . DP=6;I16=2,4,0,0,231,8931,0,0,360,21600,0,0,118,2694,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3544 . A <*> 0 . DP=6;I16=2,4,0,0,209,7513,0,0,360,21600,0,0,118,2712,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 3545 . A <*> 0 . DP=6;I16=2,4,0,0,239,9611,0,0,360,21600,0,0,118,2734,0,0;QS=1,0;MQ0F=0 PL 0,18,196 17 3546 . G <*> 0 . DP=6;I16=2,4,0,0,215,7987,0,0,360,21600,0,0,118,2760,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3547 . G <*> 0 . DP=6;I16=2,4,0,0,225,8687,0,0,360,21600,0,0,118,2790,0,0;QS=1,0;MQ0F=0 PL 0,18,187 17 3548 . A <*> 0 . DP=6;I16=2,4,0,0,216,8006,0,0,360,21600,0,0,118,2824,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3549 . T <*> 0 . DP=5;I16=2,3,0,0,175,6189,0,0,300,18000,0,0,119,2861,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3550 . A <*> 0 . DP=5;I16=2,3,0,0,199,7923,0,0,300,18000,0,0,120,2900,0,0;QS=1,0;MQ0F=0 PL 0,15,173 17 3551 . T <*> 0 . DP=5;I16=2,3,0,0,186,6994,0,0,300,18000,0,0,121,2941,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3552 . A <*> 0 . DP=5;I16=2,3,0,0,181,6745,0,0,300,18000,0,0,122,2984,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3553 . T <*> 0 . DP=6;I16=2,4,0,0,223,8379,0,0,360,21600,0,0,123,3029,0,0;QS=1,0;MQ0F=0 PL 0,18,183 17 3554 . A <*> 0 . DP=6;I16=2,4,0,0,217,8035,0,0,360,21600,0,0,124,3028,0,0;QS=1,0;MQ0F=0 PL 0,18,179 17 3555 . C <*> 0 . DP=6;I16=2,4,0,0,199,6787,0,0,360,21600,0,0,125,3033,0,0;QS=1,0;MQ0F=0 PL 0,18,163 17 3556 . G <*> 0 . DP=6;I16=2,4,0,0,210,7440,0,0,360,21600,0,0,125,2993,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 3557 . C <*> 0 . DP=6;I16=2,4,0,0,200,6950,0,0,360,21600,0,0,125,2957,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 3558 . G <*> 0 . DP=6;I16=2,4,0,0,209,7397,0,0,360,21600,0,0,125,2925,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 3559 . T <*> 0 . DP=6;I16=2,4,0,0,234,9146,0,0,360,21600,0,0,125,2897,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3560 . G <*> 0 . DP=6;I16=2,4,0,0,237,9417,0,0,360,21600,0,0,125,2873,0,0;QS=1,0;MQ0F=0 PL 0,18,194 17 3561 . A <*> 0 . DP=6;I16=2,4,0,0,240,9630,0,0,360,21600,0,0,125,2853,0,0;QS=1,0;MQ0F=0 PL 0,18,196 17 3562 . A <*> 0 . DP=7;I16=3,4,0,0,263,10181,0,0,420,25200,0,0,125,2837,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 3563 . A <*> 0 . DP=7;I16=3,4,0,0,274,10832,0,0,420,25200,0,0,126,2826,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 3564 . T <*> 0 . DP=7;I16=3,4,0,0,266,10308,0,0,420,25200,0,0,127,2821,0,0;QS=1,0;MQ0F=0 PL 0,21,214 17 3565 . T <*> 0 . DP=7;I16=3,4,0,0,263,10039,0,0,420,25200,0,0,128,2822,0,0;QS=1,0;MQ0F=0 PL 0,21,212 17 3566 . C <*> 0 . DP=7;I16=3,4,0,0,260,9918,0,0,420,25200,0,0,129,2829,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3567 . A <*> 0 . DP=7;I16=3,4,0,0,279,11143,0,0,420,25200,0,0,130,2842,0,0;QS=1,0;MQ0F=0 PL 0,21,222 17 3568 . A <*> 0 . DP=7;I16=3,4,0,0,283,11633,0,0,420,25200,0,0,131,2861,0,0;QS=1,0;MQ0F=0 PL 0,21,228 17 3569 . G <*> 0 . DP=7;I16=3,4,0,0,251,9275,0,0,420,25200,0,0,132,2886,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 3570 . T <*> 0 . DP=7;I16=3,4,0,0,264,10100,0,0,420,25200,0,0,132,2868,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 3571 . C <*> 0 . DP=7;I16=3,4,0,0,269,10383,0,0,420,25200,0,0,132,2858,0,0;QS=1,0;MQ0F=0 PL 0,21,215 17 3572 . A <*> 0 . DP=7;I16=3,4,0,0,273,10723,0,0,420,25200,0,0,132,2856,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 3573 . A <*> 0 . DP=7;I16=3,4,0,0,276,10936,0,0,420,25200,0,0,131,2813,0,0;QS=1,0;MQ0F=0 PL 0,21,220 17 3574 . T <*> 0 . DP=7;I16=3,4,0,0,274,10758,0,0,420,25200,0,0,130,2780,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 3575 . G <*> 0 . DP=7;I16=3,4,0,0,263,10063,0,0,420,25200,0,0,129,2757,0,0;QS=1,0;MQ0F=0 PL 0,21,212 17 3576 . A <*> 0 . DP=7;I16=3,4,0,0,265,10175,0,0,420,25200,0,0,128,2744,0,0;QS=1,0;MQ0F=0 PL 0,21,213 17 3577 . C <*> 0 . DP=7;I16=3,4,0,0,265,10095,0,0,420,25200,0,0,127,2741,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 3578 . A <*> 0 . DP=7;I16=3,4,0,0,272,10646,0,0,420,25200,0,0,126,2748,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 3579 . A <*> 0 . DP=6;I16=3,3,0,0,227,8823,0,0,360,21600,0,0,125,2713,0,0;QS=1,0;MQ0F=0 PL 0,18,192 17 3580 . A <*> 0 . DP=6;I16=3,3,0,0,240,9650,0,0,360,21600,0,0,124,2684,0,0;QS=1,0;MQ0F=0 PL 0,18,201 17 3581 . T <*> 0 . DP=6;I16=3,3,0,0,238,9490,0,0,360,21600,0,0,123,2661,0,0;QS=1,0;MQ0F=0 PL 0,18,199 17 3582 . C <*> 0 . DP=6;I16=3,3,0,0,239,9595,0,0,360,21600,0,0,122,2644,0,0;QS=1,0;MQ0F=0 PL 0,18,201 17 3583 . A <*> 0 . DP=7;I16=4,3,0,0,276,10996,0,0,420,25200,0,0,121,2633,0,0;QS=1,0;MQ0F=0 PL 0,21,222 17 3584 . G <*> 0 . DP=7;I16=4,3,0,0,271,10633,0,0,420,25200,0,0,121,2629,0,0;QS=1,0;MQ0F=0 PL 0,21,218 17 3585 . A <*> 0 . DP=8;I16=5,3,0,0,301,11477,0,0,480,28800,0,0,121,2633,0,0;QS=1,0;MQ0F=0 PL 0,24,229 17 3586 . A <*> 0 . DP=8;I16=5,3,0,0,308,11984,0,0,480,28800,0,0,122,2646,0,0;QS=1,0;MQ0F=0 PL 0,24,234 17 3587 . G A,<*> 0 . DP=8;I16=0,0,5,3,0,0,314,12410,0,0,480,28800,0,0,123,2669;QS=0,1,0;VDB=0.92727;SGB=-0.651104;MQSBZ=0;MQ0F=0 PL 240,24,0,240,24,240 17 3588 . A <*> 0 . DP=8;I16=5,3,0,0,313,12383,0,0,480,28800,0,0,123,2651,0,0;QS=1,0;MQ0F=0 PL 0,24,239 17 3589 . A <*> 0 . DP=8;I16=5,3,0,0,293,10975,0,0,480,28800,0,0,123,2641,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 3590 . A <*> 0 . DP=8;I16=5,3,0,0,296,11288,0,0,480,28800,0,0,123,2639,0,0;QS=1,0;MQ0F=0 PL 0,24,227 17 3591 . A <*> 0 . DP=8;I16=5,3,0,0,301,11505,0,0,480,28800,0,0,123,2645,0,0;QS=1,0;MQ0F=0 PL 0,24,230 17 3592 . A <*> 0 . DP=8;I16=5,3,0,0,284,10154,0,0,480,28800,0,0,122,2610,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 3593 . A <*> 0 . DP=8;I16=5,3,0,0,289,10547,0,0,480,28800,0,0,121,2585,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 3594 . C <*> 0 . DP=8;I16=5,3,0,0,285,10221,0,0,480,28800,0,0,120,2570,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 3595 . A <*> 0 . DP=7;I16=5,2,0,0,260,9720,0,0,420,25200,0,0,120,2564,0,0;QS=1,0;MQ0F=0 PL 0,21,199 17 3596 . T <*> 0 . DP=7;I16=5,2,0,0,237,8595,0,0,420,25200,0,0,120,2566,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 3597 . A <*> 0 . DP=7;I16=5,2,0,0,266,10166,0,0,420,25200,0,0,120,2576,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 3598 . T <*> 0 . DP=7;I16=6,1,0,0,221,7401,0,0,420,25200,0,0,121,2593,0,0;QS=1,0;MQ0F=0 PL 0,21,162 17 3599 . A <*> 0 . DP=7;I16=6,1,0,0,259,9753,0,0,420,25200,0,0,123,2617,0,0;QS=1,0;MQ0F=0 PL 0,21,184 17 3600 . T <*> 0 . DP=7;I16=6,1,0,0,259,9719,0,0,420,25200,0,0,125,2649,0,0;QS=1,0;MQ0F=0 PL 0,21,184 17 3601 . A <*> 0 . DP=7;I16=6,1,0,0,262,9952,0,0,420,25200,0,0,127,2689,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 3602 . T <*> 0 . DP=7;I16=6,1,0,0,240,8648,0,0,420,25200,0,0,129,2737,0,0;QS=1,0;MQ0F=0 PL 0,21,174 17 3603 . A <*> 0 . DP=8;I16=6,2,0,0,298,11242,0,0,480,28800,0,0,131,2793,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 3604 . C <*> 0 . DP=8;I16=6,2,0,0,276,9716,0,0,480,28800,0,0,134,2858,0,0;QS=1,0;MQ0F=0 PL 0,24,201 17 3605 . G <*> 0 . DP=8;I16=6,2,0,0,233,7485,0,0,480,28800,0,0,137,2933,0,0;QS=1,0;MQ0F=0 PL 0,24,175 17 3606 . C <*> 0 . DP=9;I16=6,3,0,0,319,11567,0,0,540,32400,0,0,139,2969,0,0;QS=1,0;MQ0F=0 PL 0,27,231 17 3607 . A <*> 0 . DP=9;I16=6,3,0,0,321,11705,0,0,540,32400,0,0,142,3018,0,0;QS=1,0;MQ0F=0 PL 0,27,232 17 3608 . A <*> 0 . DP=9;I16=6,3,0,0,316,11960,0,0,540,32400,0,0,145,3081,0,0;QS=1,0;MQ0F=0 PL 0,27,233 17 3609 . A <*> 0 . DP=9;I16=6,3,0,0,328,12274,0,0,540,32400,0,0,147,3107,0,0;QS=1,0;MQ0F=0 PL 0,27,238 17 3610 . C A,<*> 0 . DP=9;I16=5,3,1,0,292,10792,8,64,480,28800,60,3600,124,2520,25,625;QS=0.973333,0.0266667,0;SGB=-0.379885;RPBZ=-0.387298;MQBZ=0;MQSBZ=0;BQBZ=-1.62549;SCBZ=-0.53033;MQ0F=0 PL 0,17,213,24,216,214 17 3611 . C <*> 0 . DP=9;I16=6,3,0,0,316,12098,0,0,540,32400,0,0,150,3144,0,0;QS=1,0;MQ0F=0 PL 0,27,234 17 3612 . A <*> 0 . DP=9;I16=6,3,0,0,341,13619,0,0,540,32400,0,0,151,3153,0,0;QS=1,0;MQ0F=0 PL 0,27,251 17 3613 . G <*> 0 . DP=9;I16=6,3,0,0,306,11050,0,0,540,32400,0,0,152,3172,0,0;QS=1,0;MQ0F=0 PL 0,27,226 17 3614 . T <*> 0 . DP=9;I16=6,3,0,0,325,12303,0,0,540,32400,0,0,153,3201,0,0;QS=1,0;MQ0F=0 PL 0,27,237 17 3615 . A <*> 0 . DP=9;I16=6,3,0,0,334,12778,0,0,540,32400,0,0,154,3240,0,0;QS=1,0;MQ0F=0 PL 0,27,242 17 3616 . T <*> 0 . DP=9;I16=6,3,0,0,326,12352,0,0,540,32400,0,0,155,3289,0,0;QS=1,0;MQ0F=0 PL 0,27,239 17 3617 . C <*> 0 . DP=8;I16=5,3,0,0,279,10217,0,0,480,28800,0,0,157,3347,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 3618 . C <*> 0 . DP=8;I16=5,3,0,0,293,11011,0,0,480,28800,0,0,159,3413,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 3619 . T <*> 0 . DP=8;I16=5,3,0,0,312,12390,0,0,480,28800,0,0,161,3487,0,0;QS=1,0;MQ0F=0 PL 0,24,238 17 3620 . A <*> 0 . DP=8;I16=5,3,0,0,277,9805,0,0,480,28800,0,0,163,3569,0,0;QS=1,0;MQ0F=0 PL 0,24,212 17 3621 . C <*> 0 . DP=8;I16=5,3,0,0,303,11555,0,0,480,28800,0,0,165,3659,0,0;QS=1,0;MQ0F=0 PL 0,24,230 17 3622 . T <*> 0 . DP=8;I16=5,3,0,0,321,12935,0,0,480,28800,0,0,167,3757,0,0;QS=1,0;MQ0F=0 PL 0,24,242 17 3623 . G <*> 0 . DP=8;I16=5,3,0,0,273,9577,0,0,480,28800,0,0,169,3863,0,0;QS=1,0;MQ0F=0 PL 0,24,209 17 3624 . T <*> 0 . DP=8;I16=5,3,0,0,293,10921,0,0,480,28800,0,0,170,3926,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 3625 . G <*> 0 . DP=8;I16=5,3,0,0,288,10520,0,0,480,28800,0,0,171,3995,0,0;QS=1,0;MQ0F=0 PL 0,24,219 17 3626 . T <*> 0 . DP=9;I16=6,3,0,0,315,11289,0,0,540,32400,0,0,172,4070,0,0;QS=1,0;MQ0F=0 PL 0,27,229 17 3627 . G <*> 0 . DP=9;I16=6,3,0,0,316,11176,0,0,540,32400,0,0,174,4152,0,0;QS=1,0;MQ0F=0 PL 0,27,225 17 3628 . T <*> 0 . DP=9;I16=6,3,0,0,317,11543,0,0,540,32400,0,0,176,4242,0,0;QS=1,0;MQ0F=0 PL 0,27,232 17 3629 . G <*> 0 . DP=9;I16=6,3,0,0,329,12109,0,0,540,32400,0,0,176,4240,0,0;QS=1,0;MQ0F=0 PL 0,27,235 17 3630 . T <*> 0 . DP=9;I16=6,3,0,0,304,10838,0,0,540,32400,0,0,176,4246,0,0;QS=1,0;MQ0F=0 PL 0,27,223 17 3631 . C <*> 0 . DP=8;I16=5,3,0,0,234,7344,0,0,480,28800,0,0,177,4259,0,0;QS=1,0;MQ0F=0 PL 0,24,181 17 3632 . G <*> 0 . DP=8;I16=5,3,0,0,233,7367,0,0,480,28800,0,0,177,4227,0,0;QS=1,0;MQ0F=0 PL 0,24,181 17 3633 . T <*> 0 . DP=8;I16=5,3,0,0,285,10787,0,0,480,28800,0,0,177,4199,0,0;QS=1,0;MQ0F=0 PL 0,24,222 17 3634 . T <*> 0 . DP=8;I16=5,3,0,0,290,11190,0,0,480,28800,0,0,177,4175,0,0;QS=1,0;MQ0F=0 PL 0,24,227 17 3635 . T <*> 0 . DP=8;I16=5,3,0,0,293,10913,0,0,480,28800,0,0,177,4155,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 3636 . G <*> 0 . DP=8;I16=5,3,0,0,283,10257,0,0,480,28800,0,0,177,4139,0,0;QS=1,0;MQ0F=0 PL 0,24,217 17 3637 . T <*> 0 . DP=8;I16=5,3,0,0,314,12504,0,0,480,28800,0,0,177,4127,0,0;QS=1,0;MQ0F=0 PL 0,24,240 17 3638 . T <*> 0 . DP=8;I16=5,3,0,0,288,10660,0,0,480,28800,0,0,176,4070,0,0;QS=1,0;MQ0F=0 PL 0,24,222 17 3639 . G <*> 0 . DP=9;I16=6,3,0,0,308,10662,0,0,540,32400,0,0,175,4019,0,0;QS=1,0;MQ0F=0 PL 0,27,221 17 3640 . T <*> 0 . DP=9;I16=6,3,0,0,315,11283,0,0,540,32400,0,0,175,3975,0,0;QS=1,0;MQ0F=0 PL 0,27,229 17 3641 . G <*> 0 . DP=9;I16=6,3,0,0,309,10867,0,0,540,32400,0,0,175,3939,0,0;QS=1,0;MQ0F=0 PL 0,27,224 17 3642 . T G,<*> 0 . DP=9;I16=5,3,1,0,293,11005,3,9,480,28800,60,3600,150,3286,25,625;QS=0.986532,0.013468,0;SGB=-0.379885;RPBZ=0.387298;MQBZ=0;MQSBZ=0;BQBZ=-1.55569;SCBZ=-0.53033;MQ0F=0 PL 0,18,219,24,222,219 17 3643 . T <*> 0 . DP=9;I16=6,3,0,0,312,11318,0,0,540,32400,0,0,175,3891,0,0;QS=1,0;MQ0F=0 PL 0,27,230 17 3644 . T <*> 0 . DP=9;I16=6,3,0,0,316,12098,0,0,540,32400,0,0,175,3879,0,0;QS=1,0;MQ0F=0 PL 0,27,237 17 3645 . T <*> 0 . DP=9;I16=6,3,0,0,326,12228,0,0,540,32400,0,0,175,3875,0,0;QS=1,0;MQ0F=0 PL 0,27,239 17 3646 . C <*> 0 . DP=9;I16=6,3,0,0,252,7724,0,0,540,32400,0,0,175,3879,0,0;QS=1,0;MQ0F=0 PL 0,27,188 17 3647 . G T,<*> 0 . DP=9;I16=5,3,1,0,214,7092,12,144,480,28800,60,3600,150,3266,25,625;QS=0.947368,0.0526316,0;SGB=-0.379885;RPBZ=0.387298;MQBZ=0;MQSBZ=0;BQBZ=-1.1619;SCBZ=-0.53033;MQ0F=0 PL 0,14,162,24,165,165 17 3648 . A <*> 0 . DP=9;I16=6,3,0,0,304,11112,0,0,540,32400,0,0,175,3911,0,0;QS=1,0;MQ0F=0 PL 0,27,227 17 3649 . C <*> 0 . DP=9;I16=6,3,0,0,309,10981,0,0,540,32400,0,0,175,3939,0,0;QS=1,0;MQ0F=0 PL 0,27,226 17 3650 . A <*> 0 . DP=9;I16=6,3,0,0,335,12925,0,0,540,32400,0,0,175,3975,0,0;QS=1,0;MQ0F=0 PL 0,27,246 17 3651 . G <*> 0 . DP=9;I16=6,3,0,0,320,11684,0,0,540,32400,0,0,175,4019,0,0;QS=1,0;MQ0F=0 PL 0,27,233 17 3652 . C <*> 0 . DP=9;I16=6,3,0,0,303,10767,0,0,540,32400,0,0,174,4020,0,0;QS=1,0;MQ0F=0 PL 0,27,225 17 3653 . T <*> 0 . DP=9;I16=6,3,0,0,318,11448,0,0,540,32400,0,0,173,4027,0,0;QS=1,0;MQ0F=0 PL 0,27,230 17 3654 . G <*> 0 . DP=8;I16=6,2,0,0,230,8190,0,0,480,28800,0,0,173,4039,0,0;QS=1,0;MQ0F=0 PL 0,24,181 17 3655 . T <*> 0 . DP=7;I16=5,2,0,0,222,7766,0,0,420,25200,0,0,166,4006,0,0;QS=1,0;MQ0F=0 PL 0,21,179 17 3656 . C <*> 0 . DP=7;I16=5,2,0,0,241,8827,0,0,420,25200,0,0,167,4039,0,0;QS=1,0;MQ0F=0 PL 0,21,191 17 3657 . C <*> 0 . DP=7;I16=5,2,0,0,245,8875,0,0,420,25200,0,0,168,4074,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 3658 . G <*> 0 . DP=7;I16=5,2,0,0,204,6582,0,0,420,25200,0,0,169,4111,0,0;QS=1,0;MQ0F=0 PL 0,21,163 17 3659 . T <*> 0 . DP=7;I16=5,2,0,0,235,8387,0,0,420,25200,0,0,169,4101,0,0;QS=1,0;MQ0F=0 PL 0,21,186 17 3660 . G <*> 0 . DP=7;I16=5,2,0,0,215,7415,0,0,420,25200,0,0,169,4095,0,0;QS=1,0;MQ0F=0 PL 0,21,174 17 3661 . T <*> 0 . DP=7;I16=5,2,0,0,234,8550,0,0,420,25200,0,0,168,4044,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 3662 . T G,<*> 0 . DP=7;I16=4,2,1,0,222,8532,10,100,360,21600,60,3600,146,3558,21,441;QS=0.956897,0.0431034,0;SGB=-0.379885;RPBZ=1;MQBZ=0;MQSBZ=0;BQBZ=-1.51357;SCBZ=-0.408248;MQ0F=0 PL 0,10,175,18,178,178 17 3663 . A <*> 0 . DP=7;I16=5,2,0,0,231,8235,0,0,420,25200,0,0,166,3960,0,0;QS=1,0;MQ0F=0 PL 0,21,183 17 3664 . T <*> 0 . DP=7;I16=5,2,0,0,250,9272,0,0,420,25200,0,0,165,3927,0,0;QS=1,0;MQ0F=0 PL 0,21,196 17 3665 . A <*> 0 . DP=7;I16=5,2,0,0,271,10551,0,0,420,25200,0,0,163,3849,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 3666 . A <*> 0 . DP=7;I16=5,2,0,0,267,10509,0,0,420,25200,0,0,161,3775,0,0;QS=1,0;MQ0F=0 PL 0,21,208 17 3667 . T <*> 0 . DP=7;I16=5,2,0,0,243,9117,0,0,420,25200,0,0,159,3705,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 3668 . A <*> 0 . DP=7;I16=5,2,0,0,273,10697,0,0,420,25200,0,0,157,3639,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3669 . A <*> 0 . DP=7;I16=5,2,0,0,270,10572,0,0,420,25200,0,0,155,3577,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3670 . T <*> 0 . DP=8;I16=6,2,0,0,305,11743,0,0,480,28800,0,0,153,3519,0,0;QS=1,0;MQ0F=0 PL 0,24,220 17 3671 . T <*> 0 . DP=8;I16=6,2,0,0,298,11356,0,0,480,28800,0,0,152,3466,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 3672 . C <*> 0 . DP=8;I16=6,2,0,0,265,10101,0,0,480,28800,0,0,151,3419,0,0;QS=1,0;MQ0F=0 PL 0,24,203 17 3673 . C <*> 0 . DP=8;I16=6,2,0,0,304,11654,0,0,480,28800,0,0,138,3234,0,0;QS=1,0;MQ0F=0 PL 0,24,219 17 3674 . T <*> 0 . DP=8;I16=6,2,0,0,313,12475,0,0,480,28800,0,0,138,3174,0,0;QS=1,0;MQ0F=0 PL 0,24,228 17 3675 . C <*> 0 . DP=8;I16=6,2,0,0,308,11960,0,0,480,28800,0,0,138,3122,0,0;QS=1,0;MQ0F=0 PL 0,24,222 17 3676 . T <*> 0 . DP=8;I16=6,2,0,0,320,12888,0,0,480,28800,0,0,138,3078,0,0;QS=1,0;MQ0F=0 PL 0,24,231 17 3677 . A <*> 0 . DP=8;I16=6,2,0,0,301,11433,0,0,480,28800,0,0,138,3042,0,0;QS=1,0;MQ0F=0 PL 0,24,217 17 3678 . G <*> 0 . DP=8;I16=6,2,0,0,298,11246,0,0,480,28800,0,0,138,3014,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 3679 . T <*> 0 . DP=8;I16=6,2,0,0,316,12560,0,0,480,28800,0,0,137,2945,0,0;QS=1,0;MQ0F=0 PL 0,24,227 17 3680 . T <*> 0 . DP=8;I16=6,2,0,0,271,9679,0,0,480,28800,0,0,136,2886,0,0;QS=1,0;MQ0F=0 PL 0,24,202 17 3681 . C <*> 0 . DP=8;I16=6,2,0,0,298,11278,0,0,480,28800,0,0,135,2837,0,0;QS=1,0;MQ0F=0 PL 0,24,217 17 3682 . A <*> 0 . DP=8;I16=6,2,0,0,314,12356,0,0,480,28800,0,0,133,2749,0,0;QS=1,0;MQ0F=0 PL 0,24,224 17 3683 . A <*> 0 . DP=8;I16=6,2,0,0,318,12722,0,0,480,28800,0,0,131,2673,0,0;QS=1,0;MQ0F=0 PL 0,24,228 17 3684 . A <*> 0 . DP=7;I16=5,2,0,0,278,11164,0,0,420,25200,0,0,130,2608,0,0;QS=1,0;MQ0F=0 PL 0,21,215 17 3685 . T <*> 0 . DP=7;I16=5,2,0,0,270,10488,0,0,420,25200,0,0,129,2553,0,0;QS=1,0;MQ0F=0 PL 0,21,207 17 3686 . T <*> 0 . DP=7;I16=5,2,0,0,283,11465,0,0,420,25200,0,0,128,2508,0,0;QS=1,0;MQ0F=0 PL 0,21,216 17 3687 . T <*> 0 . DP=8;I16=5,3,0,0,303,11529,0,0,457,26569,0,0,127,2473,0,0;QS=1,0;MQ0F=0 PL 0,24,229 17 3688 . A <*> 0 . DP=8;I16=5,3,0,0,306,11764,0,0,457,26569,0,0,127,2449,0,0;QS=1,0;MQ0F=0 PL 0,24,232 17 3689 . T <*> 0 . DP=8;I16=5,3,0,0,308,11936,0,0,457,26569,0,0,127,2437,0,0;QS=1,0;MQ0F=0 PL 0,24,233 17 3690 . T <*> 0 . DP=8;I16=5,3,0,0,297,11169,0,0,457,26569,0,0,127,2437,0,0;QS=1,0;MQ0F=0 PL 0,24,225 17 3691 . C <*> 0 . DP=8;I16=5,3,0,0,278,10416,0,0,457,26569,0,0,127,2449,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 3692 . A <*> 0 . DP=8;I16=5,3,0,0,271,9827,0,0,457,26569,0,0,127,2473,0,0;QS=1,0;MQ0F=0 PL 0,24,209 17 3693 . T <*> 0 . DP=8;I16=5,3,0,0,304,11616,0,0,457,26569,0,0,127,2509,0,0;QS=1,0;MQ0F=0 PL 0,24,230 17 3694 . T <*> 0 . DP=8;I16=5,3,0,0,311,12217,0,0,457,26569,0,0,127,2557,0,0;QS=1,0;MQ0F=0 PL 0,24,234 17 3695 . T <*> 0 . DP=8;I16=5,3,0,0,307,11897,0,0,457,26569,0,0,127,2617,0,0;QS=1,0;MQ0F=0 PL 0,24,233 17 3696 . T <*> 0 . DP=8;I16=5,3,0,0,310,12100,0,0,457,26569,0,0,126,2638,0,0;QS=1,0;MQ0F=0 PL 0,24,235 17 3697 . T <*> 0 . DP=8;I16=5,3,0,0,298,11308,0,0,457,26569,0,0,125,2669,0,0;QS=1,0;MQ0F=0 PL 0,24,229 17 3698 . A <*> 0 . DP=8;I16=5,3,0,0,307,11825,0,0,457,26569,0,0,124,2710,0,0;QS=1,0;MQ0F=0 PL 0,24,232 17 3699 . A <*> 0 . DP=7;I16=4,3,0,0,281,11403,0,0,397,22969,0,0,123,2709,0,0;QS=1,0;MQ0F=0 PL 0,21,226 17 3700 . C <*> 0 . DP=8;I16=5,3,0,0,277,9883,0,0,457,26569,0,0,122,2714,0,0;QS=1,0;MQ0F=0 PL 0,24,212 17 3701 . T <*> 0 . DP=8;I16=5,3,0,0,302,11782,0,0,457,26569,0,0,122,2726,0,0;QS=1,0;MQ0F=0 PL 0,24,233 17 3702 . T <*> 0 . DP=8;I16=5,3,0,0,280,10544,0,0,457,26569,0,0,121,2697,0,0;QS=1,0;MQ0F=0 PL 0,24,215 17 3703 . C <*> 0 . DP=8;I16=5,3,0,0,303,11597,0,0,457,26569,0,0,120,2678,0,0;QS=1,0;MQ0F=0 PL 0,24,232 17 3704 . A <*> 0 . DP=7;I16=5,2,0,0,274,10762,0,0,397,22969,0,0,120,2668,0,0;QS=1,0;MQ0F=0 PL 0,21,211 17 3705 . T <*> 0 . DP=7;I16=5,2,0,0,274,10748,0,0,397,22969,0,0,120,2666,0,0;QS=1,0;MQ0F=0 PL 0,21,209 17 3706 . A <*> 0 . DP=7;I16=5,2,0,0,267,10265,0,0,397,22969,0,0,120,2672,0,0;QS=1,0;MQ0F=0 PL 0,21,204 17 3707 . G <*> 0 . DP=6;I16=5,1,0,0,216,8272,0,0,337,19369,0,0,121,2685,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 3708 . T <*> 0 . DP=6;I16=5,1,0,0,204,7724,0,0,337,19369,0,0,122,2704,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 3709 . A <*> 0 . DP=6;I16=5,1,0,0,211,7631,0,0,337,19369,0,0,123,2729,0,0;QS=1,0;MQ0F=0 PL 0,18,162 17 3710 . C <*> 0 . DP=6;I16=5,1,0,0,210,7664,0,0,337,19369,0,0,124,2760,0,0;QS=1,0;MQ0F=0 PL 0,18,159 17 3711 . C <*> 0 . DP=6;I16=5,1,0,0,229,9019,0,0,337,19369,0,0,125,2797,0,0;QS=1,0;MQ0F=0 PL 0,18,173 17 3712 . A <*> 0 . DP=6;I16=5,1,0,0,222,8658,0,0,337,19369,0,0,126,2840,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 3713 . C <*> 0 . DP=6;I16=5,1,0,0,219,8299,0,0,337,19369,0,0,126,2838,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 3714 . A <*> 0 . DP=6;I16=5,1,0,0,230,8914,0,0,337,19369,0,0,126,2840,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 3715 . T <*> 0 . DP=6;I16=5,1,0,0,214,7926,0,0,337,19369,0,0,125,2797,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 3716 . T <*> 0 . DP=6;I16=5,1,0,0,218,8322,0,0,337,19369,0,0,124,2760,0,0;QS=1,0;MQ0F=0 PL 0,18,164 17 3717 . C <*> 0 . DP=6;I16=5,1,0,0,222,8600,0,0,337,19369,0,0,123,2729,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 3718 . T <*> 0 . DP=6;I16=5,1,0,0,223,9053,0,0,337,19369,0,0,122,2704,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 3719 . A T,<*> 0 . DP=6;I16=5,0,0,1,200,8050,12,144,300,18000,37,1369,96,2060,25,625;QS=0.943396,0.0566038,0;SGB=-0.379885;RPBZ=-0.87831;MQBZ=-2.23607;MQSBZ=-2.23607;BQBZ=-1.46385;SCBZ=0;MQ0F=0 PL 0,5,133,15,136,137 17 3720 . C <*> 0 . DP=6;I16=5,1,0,0,212,7920,0,0,337,19369,0,0,120,2672,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 3721 . A C,<*> 0 . DP=6;I16=5,0,0,1,205,8415,4,16,300,18000,37,1369,94,2040,25,625;QS=0.980861,0.0191388,0;SGB=-0.379885;RPBZ=-0.87831;MQBZ=-2.23607;MQSBZ=-2.23607;BQBZ=-1.46385;SCBZ=0;MQ0F=0 PL 0,10,140,15,143,140 17 3722 . C <*> 0 . DP=6;I16=5,1,0,0,220,8352,0,0,337,19369,0,0,118,2664,0,0;QS=1,0;MQ0F=0 PL 0,18,165 17 3723 . A G,<*> 0 . DP=6;I16=5,0,0,1,205,8419,8,64,300,18000,37,1369,92,2044,25,625;QS=0.962441,0.0375587,0;SGB=-0.379885;RPBZ=-0.87831;MQBZ=-2.23607;MQSBZ=-2.23607;BQBZ=-1.50756;SCBZ=0;MQ0F=0 PL 0,8,138,15,141,140 17 3724 . C <*> 0 . DP=6;I16=5,1,0,0,222,8374,0,0,337,19369,0,0,116,2680,0,0;QS=1,0;MQ0F=0 PL 0,18,169 17 3725 . T <*> 0 . DP=6;I16=5,1,0,0,249,10441,0,0,337,19369,0,0,115,2697,0,0;QS=1,0;MQ0F=0 PL 0,18,190 17 3726 . G <*> 0 . DP=6;I16=5,1,0,0,215,8133,0,0,337,19369,0,0,113,2669,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 3727 . C <*> 0 . DP=5;I16=4,1,0,0,176,6630,0,0,277,15769,0,0,112,2644,0,0;QS=1,0;MQ0F=0 PL 0,15,143 17 3728 . C <*> 0 . DP=5;I16=4,1,0,0,195,7761,0,0,277,15769,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,160 17 3729 . C <*> 0 . DP=5;I16=4,1,0,0,201,8161,0,0,277,15769,0,0,110,2600,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3730 . A <*> 0 . DP=5;I16=4,1,0,0,193,7539,0,0,277,15769,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 3731 . T <*> 0 . DP=5;I16=4,1,0,0,175,6735,0,0,277,15769,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,139 17 3732 . G <*> 0 . DP=5;I16=4,1,0,0,185,7171,0,0,277,15769,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,149 17 3733 . T <*> 0 . DP=5;I16=4,1,0,0,186,6972,0,0,277,15769,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3734 . C <*> 0 . DP=5;I16=4,1,0,0,187,7289,0,0,277,15769,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3735 . C <*> 0 . DP=5;I16=4,1,0,0,188,7314,0,0,277,15769,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,152 17 3736 . C <*> 0 . DP=6;I16=5,1,0,0,211,7927,0,0,337,19369,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 3737 . C <*> 0 . DP=6;I16=5,1,0,0,235,9261,0,0,337,19369,0,0,103,2505,0,0;QS=1,0;MQ0F=0 PL 0,18,178 17 3738 . T <*> 0 . DP=6;I16=5,1,0,0,248,10312,0,0,337,19369,0,0,103,2505,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3739 . C <*> 0 . DP=6;I16=5,1,0,0,240,9674,0,0,337,19369,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,18,181 17 3740 . A <*> 0 . DP=5;I16=4,1,0,0,199,7941,0,0,277,15769,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 3741 . A <*> 0 . DP=5;I16=4,1,0,0,214,9172,0,0,277,15769,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,172 17 3742 . G <*> 0 . DP=5;I16=4,1,0,0,199,8059,0,0,277,15769,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3743 . C <*> 0 . DP=5;I16=4,1,0,0,194,7698,0,0,277,15769,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3744 . T <*> 0 . DP=5;I16=4,1,0,0,202,8358,0,0,277,15769,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,164 17 3745 . T <*> 0 . DP=5;I16=4,1,0,0,195,7735,0,0,277,15769,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3746 . C <*> 0 . DP=5;I16=4,1,0,0,202,8216,0,0,277,15769,0,0,109,2551,0,0;QS=1,0;MQ0F=0 PL 0,15,165 17 3747 . C <*> 0 . DP=5;I16=4,1,0,0,199,8039,0,0,277,15769,0,0,109,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3748 . C <*> 0 . DP=5;I16=4,1,0,0,197,7839,0,0,277,15769,0,0,109,2503,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3749 . C <*> 0 . DP=5;I16=4,1,0,0,191,7515,0,0,277,15769,0,0,108,2436,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 3750 . T <*> 0 . DP=5;I16=4,1,0,0,183,7365,0,0,277,15769,0,0,107,2375,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 3751 . G <*> 0 . DP=5;I16=4,1,0,0,197,7803,0,0,277,15769,0,0,106,2320,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3752 . G <*> 0 . DP=5;I16=4,1,0,0,194,7542,0,0,277,15769,0,0,105,2271,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 3753 . C <*> 0 . DP=5;I16=4,1,0,0,200,8068,0,0,277,15769,0,0,104,2228,0,0;QS=1,0;MQ0F=0 PL 0,15,163 17 3754 . T <*> 0 . DP=5;I16=4,1,0,0,196,8150,0,0,277,15769,0,0,103,2191,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3755 . C <*> 0 . DP=5;I16=4,1,0,0,198,7938,0,0,277,15769,0,0,102,2160,0,0;QS=1,0;MQ0F=0 PL 0,15,161 17 3756 . C <*> 0 . DP=5;I16=4,1,0,0,196,7876,0,0,277,15769,0,0,101,2135,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 3757 . T <*> 0 . DP=5;I16=4,1,0,0,205,8475,0,0,277,15769,0,0,100,2116,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3758 . G <*> 0 . DP=5;I16=4,1,0,0,181,6879,0,0,277,15769,0,0,99,2103,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 3759 . C <*> 0 . DP=5;I16=4,1,0,0,173,6879,0,0,277,15769,0,0,98,2096,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 3760 . A <*> 0 . DP=6;I16=4,2,0,0,219,8519,0,0,337,19369,0,0,97,2095,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 3761 . A <*> 0 . DP=6;I16=4,2,0,0,230,9010,0,0,337,19369,0,0,97,2101,0,0;QS=1,0;MQ0F=0 PL 0,18,188 17 3762 . C <*> 0 . DP=6;I16=4,2,0,0,198,7636,0,0,337,19369,0,0,96,2064,0,0;QS=1,0;MQ0F=0 PL 0,18,161 17 3763 . C <*> 0 . DP=6;I16=4,2,0,0,226,8912,0,0,337,19369,0,0,94,1984,0,0;QS=1,0;MQ0F=0 PL 0,18,186 17 3764 . A C,<*> 0 . DP=6;I16=4,1,0,1,204,8328,8,64,300,18000,37,1369,69,1383,23,529;QS=0.962264,0.0377358,0;SGB=-0.379885;RPBZ=0.29277;MQBZ=-2.23607;MQSBZ=-1.41421;BQBZ=-1.55543;SCBZ=0;MQ0F=0 PL 0,8,159,15,162,161 17 3765 . C <*> 0 . DP=6;I16=4,2,0,0,231,8935,0,0,337,19369,0,0,90,1848,0,0;QS=1,0;MQ0F=0 PL 0,18,189 17 3766 . A <*> 0 . DP=6;I16=4,2,0,0,234,9192,0,0,337,19369,0,0,88,1792,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 3767 . A <*> 0 . DP=6;I16=4,2,0,0,232,9038,0,0,337,19369,0,0,86,1744,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 3768 . A <*> 0 . DP=6;I16=4,2,0,0,239,9569,0,0,337,19369,0,0,84,1704,0,0;QS=1,0;MQ0F=0 PL 0,18,195 17 3769 . T <*> 0 . DP=6;I16=4,2,0,0,235,9227,0,0,337,19369,0,0,82,1672,0,0;QS=1,0;MQ0F=0 PL 0,18,191 17 3770 . C <*> 0 . DP=6;I16=4,2,0,0,219,8165,0,0,337,19369,0,0,80,1648,0,0;QS=1,0;MQ0F=0 PL 0,18,180 17 3771 . T <*> 0 . DP=5;I16=3,2,0,0,180,6964,0,0,277,15769,0,0,79,1631,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3772 . A <*> 0 . DP=6;I16=3,3,0,0,190,6442,0,0,337,19369,0,0,78,1620,0,0;QS=1,0;MQ0F=0 PL 0,18,160 17 3773 . C <*> 0 . DP=6;I16=3,3,0,0,201,7161,0,0,337,19369,0,0,78,1616,0,0;QS=1,0;MQ0F=0 PL 0,18,171 17 3774 . T <*> 0 . DP=5;I16=2,3,0,0,204,8394,0,0,277,15769,0,0,79,1619,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3775 . C <*> 0 . DP=5;I16=2,3,0,0,165,6205,0,0,277,15769,0,0,80,1628,0,0;QS=1,0;MQ0F=0 PL 0,15,147 17 3776 . T <*> 0 . DP=5;I16=2,3,0,0,177,7075,0,0,277,15769,0,0,80,1594,0,0;QS=1,0;MQ0F=0 PL 0,15,158 17 3777 . C <*> 0 . DP=5;I16=2,3,0,0,192,7492,0,0,277,15769,0,0,80,1568,0,0;QS=1,0;MQ0F=0 PL 0,15,168 17 3778 . T <*> 0 . DP=5;I16=2,3,0,0,189,7607,0,0,277,15769,0,0,80,1550,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3779 . G <*> 0 . DP=5;I16=2,3,0,0,192,7422,0,0,277,15769,0,0,80,1540,0,0;QS=1,0;MQ0F=0 PL 0,15,167 17 3780 . C <*> 0 . DP=5;I16=2,3,0,0,195,7651,0,0,277,15769,0,0,80,1538,0,0;QS=1,0;MQ0F=0 PL 0,15,169 17 3781 . C <*> 0 . DP=5;I16=2,3,0,0,203,8265,0,0,277,15769,0,0,80,1544,0,0;QS=1,0;MQ0F=0 PL 0,15,175 17 3782 . T <*> 0 . DP=5;I16=2,3,0,0,201,8191,0,0,277,15769,0,0,80,1558,0,0;QS=1,0;MQ0F=0 PL 0,15,176 17 3783 . C <*> 0 . DP=5;I16=2,3,0,0,185,7031,0,0,277,15769,0,0,80,1580,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3784 . T <*> 0 . DP=5;I16=2,3,0,0,205,8463,0,0,277,15769,0,0,80,1610,0,0;QS=1,0;MQ0F=0 PL 0,15,178 17 3785 . G <*> 0 . DP=6;I16=2,3,0,0,203,8743,0,0,277,15769,0,0,80,1648,0,0;QS=1,0;MQ0F=0 PL 0,15,179 17 3786 . T <*> 0 . DP=6;I16=2,3,0,0,211,9327,0,0,277,15769,0,0,79,1643,0,0;QS=1,0;MQ0F=0 PL 0,15,186 17 3787 . G <*> 0 . DP=6;I16=2,3,0,0,199,8649,0,0,277,15769,0,0,78,1644,0,0;QS=1,0;MQ0F=0 PL 0,15,177 17 3788 . G <*> 0 . DP=5;I16=2,2,0,0,175,8017,0,0,240,14400,0,0,78,1650,0,0;QS=1,0;MQ0F=0 PL 0,12,161 17 3789 . G <*> 0 . DP=5;I16=2,2,0,0,175,8009,0,0,240,14400,0,0,78,1660,0,0;QS=1,0;MQ0F=0 PL 0,12,161 17 3790 . T <*> 0 . DP=5;I16=2,2,0,0,172,7826,0,0,240,14400,0,0,78,1674,0,0;QS=1,0;MQ0F=0 PL 0,12,159 17 3791 . T <*> 0 . DP=5;I16=2,2,0,0,172,7862,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,159 17 3792 . G <*> 0 . DP=5;I16=2,2,0,0,170,7652,0,0,240,14400,0,0,78,1714,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3793 . A <*> 0 . DP=5;I16=2,2,0,0,172,7794,0,0,240,14400,0,0,78,1740,0,0;QS=1,0;MQ0F=0 PL 0,12,159 17 3794 . C <*> 0 . DP=5;I16=2,2,0,0,170,7644,0,0,240,14400,0,0,78,1770,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3795 . C <*> 0 . DP=5;I16=2,2,0,0,175,8017,0,0,240,14400,0,0,78,1804,0,0;QS=1,0;MQ0F=0 PL 0,12,161 17 3796 . T <*> 0 . DP=5;I16=2,2,0,0,178,8246,0,0,240,14400,0,0,78,1842,0,0;QS=1,0;MQ0F=0 PL 0,12,164 17 3797 . A <*> 0 . DP=5;I16=2,2,0,0,172,7786,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,159 17 3798 . T <*> 0 . DP=5;I16=2,2,0,0,179,8333,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,165 17 3799 . T <*> 0 . DP=5;I16=2,2,0,0,174,7946,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,161 17 3800 . C <*> 0 . DP=5;I16=2,2,0,0,176,8090,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,162 17 3801 . T <*> 0 . DP=4;I16=1,2,0,0,140,6800,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,133 17 3802 . G <*> 0 . DP=4;I16=1,2,0,0,137,6565,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,130 17 3803 . G <*> 0 . DP=4;I16=1,2,0,0,136,6488,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,129 17 3804 . A <*> 0 . DP=4;I16=1,2,0,0,139,6725,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,132 17 3805 . C <*> 0 . DP=4;I16=1,2,0,0,137,6565,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,130 17 3806 . A <*> 0 . DP=4;I16=1,2,0,0,135,6413,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,128 17 3807 . C <*> 0 . DP=4;I16=1,2,0,0,121,5465,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,115 17 3808 . G <*> 0 . DP=4;I16=1,2,0,0,139,6721,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,132 17 3809 . T <*> 0 . DP=5;I16=1,3,0,0,184,8734,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,163 17 3810 . C <*> 0 . DP=5;I16=1,3,0,0,171,7731,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,153 17 3811 . A <*> 0 . DP=5;I16=1,3,0,0,178,8258,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,158 17 3812 . T <*> 0 . DP=5;I16=1,3,0,0,180,8406,0,0,240,14400,0,0,77,1835,0,0;QS=1,0;MQ0F=0 PL 0,12,160 17 3813 . A <*> 0 . DP=5;I16=1,3,0,0,192,9410,0,0,240,14400,0,0,77,1795,0,0;QS=1,0;MQ0F=0 PL 0,12,170 17 3814 . G <*> 0 . DP=5;I16=1,3,0,0,184,8730,0,0,240,14400,0,0,77,1759,0,0;QS=1,0;MQ0F=0 PL 0,12,163 17 3815 . A <*> 0 . DP=5;I16=1,3,0,0,183,8643,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQ0F=0 PL 0,12,162 17 3816 . A <*> 0 . DP=5;I16=1,3,0,0,180,8414,0,0,240,14400,0,0,77,1699,0,0;QS=1,0;MQ0F=0 PL 0,12,160 17 3817 . A <*> 0 . DP=5;I16=1,3,0,0,181,8485,0,0,240,14400,0,0,77,1675,0,0;QS=1,0;MQ0F=0 PL 0,12,161 17 3818 . T <*> 0 . DP=5;I16=1,3,0,0,181,8481,0,0,240,14400,0,0,77,1655,0,0;QS=1,0;MQ0F=0 PL 0,12,160 17 3819 . A <*> 0 . DP=5;I16=1,3,0,0,189,9149,0,0,240,14400,0,0,77,1639,0,0;QS=1,0;MQ0F=0 PL 0,12,167 17 3820 . G <*> 0 . DP=5;I16=1,3,0,0,176,8106,0,0,240,14400,0,0,77,1627,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3821 . A <*> 0 . DP=5;I16=1,3,0,0,190,9238,0,0,240,14400,0,0,77,1619,0,0;QS=1,0;MQ0F=0 PL 0,12,168 17 3822 . G <*> 0 . DP=5;I16=1,3,0,0,176,8120,0,0,240,14400,0,0,77,1615,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3823 . T <*> 0 . DP=5;I16=1,3,0,0,184,8734,0,0,240,14400,0,0,77,1615,0,0;QS=1,0;MQ0F=0 PL 0,12,163 17 3824 . C <*> 0 . DP=5;I16=1,3,0,0,178,8292,0,0,240,14400,0,0,77,1619,0,0;QS=1,0;MQ0F=0 PL 0,12,159 17 3825 . C <*> 0 . DP=5;I16=1,3,0,0,176,8152,0,0,240,14400,0,0,77,1627,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3826 . T <*> 0 . DP=5;I16=1,3,0,0,173,7905,0,0,240,14400,0,0,77,1639,0,0;QS=1,0;MQ0F=0 PL 0,12,155 17 3827 . G <*> 0 . DP=5;I16=1,3,0,0,182,8570,0,0,240,14400,0,0,77,1655,0,0;QS=1,0;MQ0F=0 PL 0,12,162 17 3828 . C <*> 0 . DP=5;I16=1,3,0,0,176,8126,0,0,240,14400,0,0,77,1675,0,0;QS=1,0;MQ0F=0 PL 0,12,157 17 3829 . A <*> 0 . DP=5;I16=1,3,0,0,178,8258,0,0,240,14400,0,0,77,1699,0,0;QS=1,0;MQ0F=0 PL 0,12,158 17 3830 . A <*> 0 . DP=5;I16=1,3,0,0,167,7477,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQ0F=0 PL 0,12,150 17 3831 . C <*> 0 . DP=5;I16=1,3,0,0,166,7394,0,0,240,14400,0,0,77,1759,0,0;QS=1,0;MQ0F=0 PL 0,12,149 17 3832 . A <*> 0 . DP=5;I16=1,3,0,0,155,6643,0,0,240,14400,0,0,77,1795,0,0;QS=1,0;MQ0F=0 PL 0,12,139 17 3833 . C <*> 0 . DP=5;I16=1,3,0,0,144,6104,0,0,240,14400,0,0,77,1835,0,0;QS=1,0;MQ0F=0 PL 0,12,131 17 3834 . G <*> 0 . DP=5;I16=1,3,0,0,175,8053,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,156 17 3835 . T <*> 0 . DP=5;I16=1,3,0,0,170,7726,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,153 17 3836 . G <*> 0 . DP=6;I16=2,3,0,0,213,9515,0,0,277,15769,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,15,188 17 3837 . G <*> 0 . DP=5;I16=1,4,0,0,182,6730,0,0,277,15769,0,0,99,2405,0,0;QS=1,0;MQ0F=0 PL 0,15,150 17 3838 . C <*> 0 . DP=5;I16=1,4,0,0,179,6571,0,0,277,15769,0,0,99,2363,0,0;QS=1,0;MQ0F=0 PL 0,15,148 17 3839 . C <*> 0 . DP=5;I16=1,4,0,0,139,4225,0,0,277,15769,0,0,99,2325,0,0;QS=1,0;MQ0F=0 PL 0,15,116 17 3840 . G <*> 0 . DP=5;I16=1,4,0,0,179,6539,0,0,277,15769,0,0,99,2291,0,0;QS=1,0;MQ0F=0 PL 0,15,146 17 3841 . T <*> 0 . DP=5;I16=1,4,0,0,197,7779,0,0,277,15769,0,0,99,2261,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3842 . C <*> 0 . DP=5;I16=1,4,0,0,195,7659,0,0,277,15769,0,0,99,2235,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 3843 . T <*> 0 . DP=5;I16=1,4,0,0,198,7850,0,0,277,15769,0,0,99,2213,0,0;QS=1,0;MQ0F=0 PL 0,15,159 17 3844 . G <*> 0 . DP=6;I16=1,5,0,0,227,8615,0,0,337,19369,0,0,99,2195,0,0;QS=1,0;MQ0F=0 PL 0,18,172 17 3845 . T <*> 0 . DP=6;I16=1,5,0,0,219,8109,0,0,337,19369,0,0,100,2182,0,0;QS=1,0;MQ0F=0 PL 0,18,166 17 3846 . G <*> 0 . DP=7;I16=1,6,0,0,235,8375,0,0,397,22969,0,0,101,2175,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 3847 . T <*> 0 . DP=7;I16=1,6,0,0,268,10292,0,0,397,22969,0,0,103,2175,0,0;QS=1,0;MQ0F=0 PL 0,21,189 17 3848 . C <*> 0 . DP=7;I16=1,6,0,0,264,10104,0,0,397,22969,0,0,104,2134,0,0;QS=1,0;MQ0F=0 PL 0,21,188 17 3849 . T <*> 0 . DP=7;I16=1,6,0,0,270,10434,0,0,397,22969,0,0,105,2103,0,0;QS=1,0;MQ0F=0 PL 0,21,190 17 3850 . G <*> 0 . DP=7;I16=1,6,0,0,259,9691,0,0,397,22969,0,0,106,2082,0,0;QS=1,0;MQ0F=0 PL 0,21,182 17 3851 . G <*> 0 . DP=7;I16=1,6,0,0,258,9650,0,0,397,22969,0,0,107,2071,0,0;QS=1,0;MQ0F=0 PL 0,21,183 17 3852 . C <*> 0 . DP=7;I16=1,6,0,0,253,9295,0,0,397,22969,0,0,108,2070,0,0;QS=1,0;MQ0F=0 PL 0,21,179 17 3853 . T <*> 0 . DP=7;I16=1,6,0,0,269,10669,0,0,397,22969,0,0,109,2079,0,0;QS=1,0;MQ0F=0 PL 0,21,192 17 3854 . T <*> 0 . DP=7;I16=1,6,0,0,247,9391,0,0,397,22969,0,0,110,2098,0,0;QS=1,0;MQ0F=0 PL 0,21,180 17 3855 . C <*> 0 . DP=7;I16=1,6,0,0,250,9026,0,0,397,22969,0,0,111,2127,0,0;QS=1,0;MQ0F=0 PL 0,21,175 17 3856 . T <*> 0 . DP=8;I16=1,7,0,0,266,10062,0,0,457,26569,0,0,112,2166,0,0;QS=1,0;MQ0F=0 PL 0,24,183 17 3857 . C <*> 0 . DP=8;I16=1,7,0,0,296,11064,0,0,457,26569,0,0,114,2216,0,0;QS=1,0;MQ0F=0 PL 0,24,193 17 3858 . T <*> 0 . DP=8;I16=1,7,0,0,316,12516,0,0,457,26569,0,0,116,2278,0,0;QS=1,0;MQ0F=0 PL 0,24,208 17 3859 . C <*> 0 . DP=9;I16=1,8,0,0,237,7141,0,0,517,30169,0,0,143,2977,0,0;QS=1,0;MQ0F=0 PL 0,27,154 17 3860 . G <*> 0 . DP=9;I16=1,8,0,0,332,12374,0,0,517,30169,0,0,145,3063,0,0;QS=1,0;MQ0F=0 PL 0,27,208 17 3861 . C <*> 0 . DP=8;I16=1,7,0,0,300,11478,0,0,457,26569,0,0,147,3111,0,0;QS=1,0;MQ0F=0 PL 0,24,199 17 3862 . T <*> 0 . DP=9;I16=1,8,0,0,364,14752,0,0,517,30169,0,0,148,3120,0,0;QS=1,0;MQ0F=0 PL 0,27,224 17 3863 . T <*> 0 . DP=9;I16=1,8,0,0,352,13794,0,0,517,30169,0,0,150,3140,0,0;QS=1,0;MQ0F=0 PL 0,27,213 17 3864 . A <*> 0 . DP=9;I16=1,8,0,0,372,15422,0,0,517,30169,0,0,152,3172,0,0;QS=1,0;MQ0F=0 PL 0,27,230 17 3865 . G <*> 0 . DP=9;I16=1,8,0,0,348,13486,0,0,517,30169,0,0,154,3216,0,0;QS=1,0;MQ0F=0 PL 0,27,212 17 3866 . C <*> 0 . DP=9;I16=1,8,0,0,314,11570,0,0,517,30169,0,0,156,3272,0,0;QS=1,0;MQ0F=0 PL 0,27,198 17 3867 . A <*> 0 . DP=9;I16=1,8,0,0,310,11252,0,0,517,30169,0,0,158,3340,0,0;QS=1,0;MQ0F=0 PL 0,27,195 17 3868 . T <*> 0 . DP=9;I16=1,8,0,0,360,14450,0,0,517,30169,0,0,160,3420,0,0;QS=1,0;MQ0F=0 PL 0,27,221 17 3869 . C <*> 0 . DP=9;I16=1,8,0,0,343,13105,0,0,517,30169,0,0,162,3512,0,0;QS=1,0;MQ0F=0 PL 0,27,211 17 3870 . T <*> 0 . DP=9;I16=1,8,0,0,347,13485,0,0,517,30169,0,0,163,3565,0,0;QS=1,0;MQ0F=0 PL 0,27,211 17 3871 . T <*> 0 . DP=9;I16=1,8,0,0,364,14740,0,0,517,30169,0,0,164,3628,0,0;QS=1,0;MQ0F=0 PL 0,27,223 17 3872 . G <*> 0 . DP=9;I16=1,8,0,0,328,12090,0,0,517,30169,0,0,164,3650,0,0;QS=1,0;MQ0F=0 PL 0,27,200 17 3873 . T <*> 0 . DP=8;I16=1,7,0,0,323,13061,0,0,457,26569,0,0,165,3679,0,0;QS=1,0;MQ0F=0 PL 0,24,212 17 3874 . T <*> 0 . DP=8;I16=1,7,0,0,314,12382,0,0,457,26569,0,0,166,3714,0,0;QS=1,0;MQ0F=0 PL 0,24,204 17 3875 . T <*> 0 . DP=8;I16=1,7,0,0,302,11502,0,0,457,26569,0,0,167,3755,0,0;QS=1,0;MQ0F=0 PL 0,24,197 17 3876 . C <*> 0 . DP=8;I16=1,7,0,0,280,9892,0,0,457,26569,0,0,168,3802,0,0;QS=1,0;MQ0F=0 PL 0,24,180 17 3877 . C <*> 0 . DP=8;I16=1,7,0,0,303,11539,0,0,457,26569,0,0,169,3855,0,0;QS=1,0;MQ0F=0 PL 0,24,196 17 3878 . A <*> 0 . DP=8;I16=1,7,0,0,289,10581,0,0,457,26569,0,0,170,3914,0,0;QS=1,0;MQ0F=0 PL 0,24,188 17 3879 . A <*> 0 . DP=8;I16=1,7,0,0,315,12649,0,0,457,26569,0,0,171,3979,0,0;QS=1,0;MQ0F=0 PL 0,24,206 17 3880 . G <*> 0 . DP=8;I16=1,7,0,0,281,9963,0,0,457,26569,0,0,172,4050,0,0;QS=1,0;MQ0F=0 PL 0,24,183 17 3881 . G <*> 0 . DP=8;I16=1,7,0,0,270,9222,0,0,457,26569,0,0,173,4127,0,0;QS=1,0;MQ0F=0 PL 0,24,174 17 3882 . T <*> 0 . DP=8;I16=1,7,0,0,261,9225,0,0,457,26569,0,0,173,4159,0,0;QS=1,0;MQ0F=0 PL 0,24,179 17 3883 . C <*> 0 . DP=8;I16=1,7,0,0,261,8657,0,0,457,26569,0,0,173,4195,0,0;QS=1,0;MQ0F=0 PL 0,24,171 17 3884 . C <*> 0 . DP=9;I16=2,7,0,0,308,10616,0,0,494,27938,0,0,173,4235,0,0;QS=1,0;MQ0F=0 PL 0,27,212 17 3885 . T <*> 0 . DP=9;I16=2,7,0,0,314,11326,0,0,494,27938,0,0,173,4231,0,0;QS=1,0;MQ0F=0 PL 0,27,214 17 3886 . C <*> 0 . DP=8;I16=2,6,0,0,258,8768,0,0,434,24338,0,0,174,4234,0,0;QS=1,0;MQ0F=0 PL 0,24,191 17 3887 . C <*> 0 . DP=8;I16=2,6,0,0,285,10201,0,0,434,24338,0,0,175,4243,0,0;QS=1,0;MQ0F=0 PL 0,24,201 17 3888 . C <*> 0 . DP=8;I16=2,6,0,0,290,10754,0,0,434,24338,0,0,175,4207,0,0;QS=1,0;MQ0F=0 PL 0,24,208 17 3889 . A <*> 0 . DP=8;I16=2,6,0,0,297,11309,0,0,434,24338,0,0,175,4175,0,0;QS=1,0;MQ0F=0 PL 0,24,218 17 3890 . C <*> 0 . DP=8;I16=2,6,0,0,297,11205,0,0,434,24338,0,0,175,4147,0,0;QS=1,0;MQ0F=0 PL 0,24,216 17 3891 . A <*> 0 . DP=9;I16=2,7,0,0,356,14186,0,0,494,27938,0,0,175,4123,0,0;QS=1,0;MQ0F=0 PL 0,27,242 17 3892 . G <*> 0 . DP=9;I16=2,7,0,0,310,10796,0,0,494,27938,0,0,176,4104,0,0;QS=1,0;MQ0F=0 PL 0,27,208 17 3893 . T <*> 0 . DP=9;I16=2,7,0,0,309,10945,0,0,494,27938,0,0,177,4091,0,0;QS=1,0;MQ0F=0 PL 0,27,212 17 3894 . G <*> 0 . DP=9;I16=2,7,0,0,308,10824,0,0,494,27938,0,0,178,4084,0,0;QS=1,0;MQ0F=0 PL 0,27,208 17 3895 . T <*> 0 . DP=9;I16=2,7,0,0,327,12143,0,0,494,27938,0,0,179,4083,0,0;QS=1,0;MQ0F=0 PL 0,27,225 17 3896 . A <*> 0 . DP=9;I16=2,7,0,0,339,13459,0,0,494,27938,0,0,180,4088,0,0;QS=1,0;MQ0F=0 PL 0,27,233 17 3897 . G <*> 0 . DP=10;I16=2,8,0,0,363,13537,0,0,554,31538,0,0,181,4099,0,0;QS=1,0;MQ0F=0 PL 0,30,236 17 3898 . C <*> 0 . DP=10;I16=2,8,0,0,381,14613,0,0,554,31538,0,0,183,4117,0,0;QS=1,0;MQ0F=0 PL 0,30,238 17 3899 . A <*> 0 . DP=10;I16=2,8,0,0,363,13361,0,0,554,31538,0,0,185,4143,0,0;QS=1,0;MQ0F=0 PL 0,30,231 17 3900 . T <*> 0 . DP=10;I16=2,8,0,0,377,14437,0,0,554,31538,0,0,187,4177,0,0;QS=1,0;MQ0F=0 PL 0,30,240 17 3901 . G <*> 0 . DP=10;I16=2,8,0,0,332,11724,0,0,554,31538,0,0,189,4219,0,0;QS=1,0;MQ0F=0 PL 0,30,218 17 3902 . C <*> 0 . DP=10;I16=2,8,0,0,352,12592,0,0,554,31538,0,0,191,4269,0,0;QS=1,0;MQ0F=0 PL 0,30,217 17 3903 . A C,<*> 0 . DP=11;I16=2,8,0,1,318,10522,2,4,554,31538,60,3600,193,4327,2,4;QS=0.987421,0.0125786,0;SGB=-0.379885;RPBZ=-1.58114;MQBZ=0.471405;MQSBZ=3.16228;BQBZ=-1.58474;SCBZ=2.011;MQ0F=0 PL 0,23,198,30,201,198 17 3904 . C <*> 0 . DP=11;I16=2,9,0,0,390,14732,0,0,614,35138,0,0,198,4402,0,0;QS=1,0;MQ0F=0 PL 0,33,243 17 3905 . C <*> 0 . DP=11;I16=2,9,0,0,429,16811,0,0,614,35138,0,0,201,4483,0,0;QS=1,0;MQ0F=0 PL 0,33,255 17 3906 . T <*> 0 . DP=11;I16=2,9,0,0,440,17690,0,0,614,35138,0,0,204,4574,0,0;QS=1,0;MQ0F=0 PL 0,33,253 17 3907 . G <*> 0 . DP=11;I16=2,9,0,0,413,15733,0,0,614,35138,0,0,207,4675,0,0;QS=1,0;MQ0F=0 PL 0,33,249 17 3908 . C <*> 0 . DP=11;I16=2,9,0,0,399,15107,0,0,614,35138,0,0,209,4737,0,0;QS=1,0;MQ0F=0 PL 0,33,244 17 3909 . T <*> 0 . DP=11;I16=2,9,0,0,395,14975,0,0,614,35138,0,0,211,4811,0,0;QS=1,0;MQ0F=0 PL 0,33,237 17 3910 . A <*> 0 . DP=10;I16=2,8,0,0,351,12613,0,0,554,31538,0,0,213,4845,0,0;QS=1,0;MQ0F=0 PL 0,30,224 17 3911 . C <*> 0 . DP=10;I16=2,8,0,0,338,11622,0,0,554,31538,0,0,215,4887,0,0;QS=1,0;MQ0F=0 PL 0,30,214 17 3912 . A C,<*> 0 . DP=10;I16=2,7,0,1,319,11431,16,256,494,27938,60,3600,205,4767,11,121;QS=0.951807,0.0481928,0;SGB=-0.379885;RPBZ=-1.5667;MQBZ=0.5;MQSBZ=3;BQBZ=-1.59599;SCBZ=1.07088;MQ0F=0 PL 0,14,202,27,205,208 17 3913 . C <*> 0 . DP=10;I16=2,8,0,0,369,14053,0,0,554,31538,0,0,217,4899,0,0;QS=1,0;MQ0F=0 PL 0,30,234 17 3914 . T <*> 0 . DP=10;I16=2,8,0,0,364,13634,0,0,554,31538,0,0,218,4920,0,0;QS=1,0;MQ0F=0 PL 0,30,228 17 3915 . C <*> 0 . DP=10;I16=2,8,0,0,360,13176,0,0,554,31538,0,0,219,4951,0,0;QS=1,0;MQ0F=0 PL 0,30,229 17 3916 . C <*> 0 . DP=10;I16=2,8,0,0,395,15757,0,0,554,31538,0,0,220,4992,0,0;QS=1,0;MQ0F=0 PL 0,30,251 17 3917 . T <*> 0 . DP=10;I16=2,8,0,0,408,16764,0,0,554,31538,0,0,220,4992,0,0;QS=1,0;MQ0F=0 PL 0,30,254 17 3918 . T <*> 0 . DP=10;I16=2,8,0,0,401,16219,0,0,554,31538,0,0,220,5000,0,0;QS=1,0;MQ0F=0 PL 0,30,254 17 3919 . C <*> 0 . DP=10;I16=2,8,0,0,381,14799,0,0,554,31538,0,0,220,5016,0,0;QS=1,0;MQ0F=0 PL 0,30,242 17 3920 . T <*> 0 . DP=10;I16=2,8,0,0,402,16318,0,0,554,31538,0,0,219,4991,0,0;QS=1,0;MQ0F=0 PL 0,30,251 17 3921 . T <*> 0 . DP=10;I16=2,8,0,0,378,14410,0,0,554,31538,0,0,218,4976,0,0;QS=1,0;MQ0F=0 PL 0,30,242 17 3922 . A <*> 0 . DP=10;I16=2,8,0,0,385,14999,0,0,554,31538,0,0,216,4922,0,0;QS=1,0;MQ0F=0 PL 0,30,244 17 3923 . G <*> 0 . DP=10;I16=2,8,0,0,381,14653,0,0,554,31538,0,0,213,4829,0,0;QS=1,0;MQ0F=0 PL 0,30,240 17 3924 . G <*> 0 . DP=10;I16=2,8,0,0,384,14808,0,0,554,31538,0,0,210,4746,0,0;QS=1,0;MQ0F=0 PL 0,30,247 17 3925 . G <*> 0 . DP=10;I16=2,8,0,0,382,14648,0,0,554,31538,0,0,207,4673,0,0;QS=1,0;MQ0F=0 PL 0,30,245 17 3926 . C <*> 0 . DP=10;I16=2,8,0,0,374,14196,0,0,554,31538,0,0,204,4610,0,0;QS=1,0;MQ0F=0 PL 0,30,237 17 3927 . T <*> 0 . DP=10;I16=2,8,0,0,374,14376,0,0,554,31538,0,0,200,4506,0,0;QS=1,0;MQ0F=0 PL 0,30,237 17 3928 . G <*> 0 . DP=10;I16=2,8,0,0,357,13773,0,0,554,31538,0,0,196,4410,0,0;QS=1,0;MQ0F=0 PL 0,30,233 17 3929 . A <*> 0 . DP=10;I16=2,8,0,0,342,12106,0,0,554,31538,0,0,192,4322,0,0;QS=1,0;MQ0F=0 PL 0,30,220 17 3930 . T <*> 0 . DP=10;I16=2,8,0,0,346,12322,0,0,554,31538,0,0,188,4242,0,0;QS=1,0;MQ0F=0 PL 0,30,224 17 3931 . A <*> 0 . DP=10;I16=2,8,0,0,341,12275,0,0,554,31538,0,0,184,4170,0,0;QS=1,0;MQ0F=0 PL 0,30,223 17 3932 . T <*> 0 . DP=10;I16=2,8,0,0,353,12985,0,0,554,31538,0,0,179,4057,0,0;QS=1,0;MQ0F=0 PL 0,30,231 17 3933 . T <*> 0 . DP=9;I16=2,7,0,0,309,11545,0,0,494,27938,0,0,175,3953,0,0;QS=1,0;MQ0F=0 PL 0,27,218 17 3934 . C <*> 0 . DP=9;I16=2,7,0,0,312,11150,0,0,494,27938,0,0,171,3857,0,0;QS=1,0;MQ0F=0 PL 0,27,212 17 3935 . C <*> 0 . DP=9;I16=2,7,0,0,275,8779,0,0,494,27938,0,0,167,3769,0,0;QS=1,0;MQ0F=0 PL 0,27,185 17 3936 . A G,<*> 0 . DP=9;I16=0,0,2,7,0,0,312,11304,0,0,494,27938,0,0,163,3689;QS=0,1,0;VDB=0.356759;SGB=-0.662043;MQSBZ=2.82843;MQ0F=0 PL 217,27,0,217,27,217 17 3937 . C <*> 0 . DP=8;I16=1,7,0,0,238,7390,0,0,457,26569,0,0,160,3616,0,0;QS=1,0;MQ0F=0 PL 0,24,156 17 3938 . G <*> 0 . DP=8;I16=1,7,0,0,256,8698,0,0,457,26569,0,0,156,3500,0,0;QS=1,0;MQ0F=0 PL 0,24,176 17 3939 . C <*> 0 . DP=8;I16=1,7,0,0,258,8868,0,0,457,26569,0,0,152,3392,0,0;QS=1,0;MQ0F=0 PL 0,24,176 17 3940 . A C,<*> 0 . DP=8;I16=1,6,0,1,224,7816,4,16,397,22969,60,3600,123,2667,25,625;QS=0.982143,0.0178571,0;SGB=-0.379885;RPBZ=-1.52753;MQBZ=0.377964;MQSBZ=2.64575;BQBZ=-1.52753;SCBZ=-0.377964;MQ0F=0 PL 0,15,157,21,160,157 17 3941 . C <*> 0 . DP=8;I16=1,7,0,0,264,9696,0,0,457,26569,0,0,144,3200,0,0;QS=1,0;MQ0F=0 PL 0,24,181 17 3942 . C <*> 0 . DP=8;I16=1,7,0,0,295,11227,0,0,457,26569,0,0,140,3116,0,0;QS=1,0;MQ0F=0 PL 0,24,195 17 3943 . T <*> 0 . DP=8;I16=1,7,0,0,292,10930,0,0,457,26569,0,0,136,3040,0,0;QS=1,0;MQ0F=0 PL 0,24,195 17 3944 . G <*> 0 . DP=8;I16=1,7,0,0,298,11188,0,0,457,26569,0,0,132,2972,0,0;QS=1,0;MQ0F=0 PL 0,24,195 17 3945 . C <*> 0 . DP=7;I16=1,6,0,0,249,9191,0,0,397,22969,0,0,129,2911,0,0;QS=1,0;MQ0F=0 PL 0,21,177 17 3946 . T <*> 0 . DP=7;I16=1,6,0,0,221,7929,0,0,397,22969,0,0,126,2856,0,0;QS=1,0;MQ0F=0 PL 0,21,160 17 3947 . A <*> 0 . DP=6;I16=1,5,0,0,193,6675,0,0,337,19369,0,0,124,2806,0,0;QS=1,0;MQ0F=0 PL 0,18,149 17 3948 . C <*> 0 . DP=6;I16=1,5,0,0,202,7182,0,0,337,19369,0,0,122,2760,0,0;QS=1,0;MQ0F=0 PL 0,18,155 17 3949 . A C,<*> 0 . DP=6;I16=1,4,0,1,152,5110,24,576,277,15769,60,3600,95,2093,25,625;QS=0.861272,0.138728,0;SGB=-0.379885;RPBZ=-1.46385;MQBZ=0.447214;MQSBZ=2.23607;BQBZ=-0.87831;SCBZ=-0.447214;MQ0F=0 PL 6,0,110,21,113,126 17 3950 . C <*> 0 . DP=6;I16=1,5,0,0,217,8159,0,0,337,19369,0,0,118,2680,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 3951 . T <*> 0 . DP=6;I16=1,5,0,0,194,7366,0,0,337,19369,0,0,116,2646,0,0;QS=1,0;MQ0F=0 PL 0,18,154 17 3952 . C <*> 0 . DP=6;I16=1,5,0,0,183,6271,0,0,337,19369,0,0,114,2616,0,0;QS=1,0;MQ0F=0 PL 0,18,146 17 3953 . C <*> 0 . DP=6;I16=1,5,0,0,219,8051,0,0,337,19369,0,0,112,2590,0,0;QS=1,0;MQ0F=0 PL 0,18,168 17 3954 . T <*> 0 . DP=6;I16=1,5,0,0,219,8467,0,0,337,19369,0,0,110,2568,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 3955 . T <*> 0 . DP=6;I16=1,5,0,0,232,9086,0,0,337,19369,0,0,108,2550,0,0;QS=1,0;MQ0F=0 PL 0,18,174 17 3956 . C <*> 0 . DP=6;I16=1,5,0,0,217,8207,0,0,337,19369,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,18,167 17 3957 . T <*> 0 . DP=5;I16=1,4,0,0,203,8339,0,0,277,15769,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,162 17 3958 . T <*> 0 . DP=5;I16=1,4,0,0,191,7319,0,0,277,15769,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,157 17 3959 . A <*> 0 . DP=5;I16=1,4,0,0,193,7481,0,0,277,15769,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,15,154 17 3960 . T <*> 0 . DP=5;I16=1,4,0,0,172,6168,0,0,277,15769,0,0,101,2455,0,0;QS=1,0;MQ0F=0 PL 0,15,142 17 3961 . G <*> 0 . DP=5;I16=1,4,0,0,170,6414,0,0,277,15769,0,0,99,2405,0,0;QS=1,0;MQ0F=0 PL 0,15,136 17 3962 . G <*> 0 . DP=5;I16=1,4,0,0,175,6247,0,0,277,15769,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,15,144 17 3963 . C <*> 0 . DP=4;I16=1,3,0,0,143,5263,0,0,217,12169,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,126 17 3964 . T <*> 0 . DP=4;I16=1,3,0,0,157,6207,0,0,217,12169,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,133 17 3965 . G <*> 0 . DP=4;I16=1,3,0,0,152,5830,0,0,217,12169,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,134 17 3966 . A <*> 0 . DP=4;I16=1,3,0,0,154,5986,0,0,217,12169,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,135 17 3967 . T <*> 0 . DP=4;I16=1,3,0,0,122,4810,0,0,217,12169,0,0,91,2115,0,0;QS=1,0;MQ0F=0 PL 0,12,104 17 3968 . A <*> 0 . DP=3;I16=0,3,0,0,119,4725,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,99 17 3969 . T <*> 0 . DP=3;I16=0,3,0,0,129,5549,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,108 17 3970 . T <*> 0 . DP=3;I16=0,3,0,0,125,5209,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 3971 . C <*> 0 . DP=3;I16=0,3,0,0,123,5051,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 3972 . C <*> 0 . DP=3;I16=0,3,0,0,114,4358,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 3973 . A <*> 0 . DP=3;I16=0,3,0,0,116,4486,0,0,180,10800,0,0,67,1525,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 3974 . C <*> 0 . DP=3;I16=0,3,0,0,94,2948,0,0,180,10800,0,0,65,1443,0,0;QS=1,0;MQ0F=0 PL 0,9,78 17 3975 . G <*> 0 . DP=3;I16=0,3,0,0,115,4417,0,0,180,10800,0,0,63,1365,0,0;QS=1,0;MQ0F=0 PL 0,9,96 17 3976 . C <*> 0 . DP=3;I16=0,3,0,0,116,4490,0,0,180,10800,0,0,61,1291,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 3977 . A <*> 0 . DP=3;I16=0,3,0,0,107,3829,0,0,180,10800,0,0,58,1172,0,0;QS=1,0;MQ0F=0 PL 0,9,90 17 3978 . C <*> 0 . DP=3;I16=0,3,0,0,123,5051,0,0,180,10800,0,0,55,1059,0,0;QS=1,0;MQ0F=0 PL 0,9,103 17 3979 . C <*> 0 . DP=3;I16=0,3,0,0,124,5130,0,0,180,10800,0,0,52,952,0,0;QS=1,0;MQ0F=0 PL 0,9,104 17 3980 . T <*> 0 . DP=3;I16=0,3,0,0,118,4644,0,0,180,10800,0,0,49,851,0,0;QS=1,0;MQ0F=0 PL 0,9,98 17 3981 . G <*> 0 . DP=3;I16=0,3,0,0,111,4131,0,0,180,10800,0,0,46,756,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 3982 . C <*> 0 . DP=3;I16=0,3,0,0,115,4437,0,0,180,10800,0,0,43,667,0,0;QS=1,0;MQ0F=0 PL 0,9,97 17 3983 . T <*> 0 . DP=3;I16=0,3,0,0,111,4115,0,0,180,10800,0,0,40,584,0,0;QS=1,0;MQ0F=0 PL 0,9,93 17 3984 . A <*> 0 . DP=3;I16=0,3,0,0,95,3069,0,0,180,10800,0,0,37,507,0,0;QS=1,0;MQ0F=0 PL 0,9,80 17 3985 . C <*> 0 . DP=3;I16=0,3,0,0,109,3969,0,0,180,10800,0,0,34,436,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 3986 . A <*> 0 . DP=3;I16=0,3,0,0,99,3323,0,0,180,10800,0,0,31,371,0,0;QS=1,0;MQ0F=0 PL 0,9,84 17 3987 . C <*> 0 . DP=3;I16=0,3,0,0,112,4200,0,0,180,10800,0,0,28,312,0,0;QS=1,0;MQ0F=0 PL 0,9,94 17 3988 . T <*> 0 . DP=3;I16=0,3,0,0,109,3969,0,0,180,10800,0,0,25,259,0,0;QS=1,0;MQ0F=0 PL 0,9,91 17 3989 . C <*> 0 . DP=3;I16=0,3,0,0,105,3677,0,0,180,10800,0,0,22,212,0,0;QS=1,0;MQ0F=0 PL 0,9,88 17 3990 . C <*> 0 . DP=3;I16=0,3,0,0,114,4338,0,0,180,10800,0,0,19,171,0,0;QS=1,0;MQ0F=0 PL 0,9,95 17 3991 . T <*> 0 . DP=3;I16=0,3,0,0,106,3796,0,0,180,10800,0,0,16,136,0,0;QS=1,0;MQ0F=0 PL 0,9,90 17 3992 . T <*> 0 . DP=2;I16=0,2,0,0,79,3125,0,0,120,7200,0,0,14,106,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 3993 . C <*> 0 . DP=2;I16=0,2,0,0,76,2896,0,0,120,7200,0,0,12,80,0,0;QS=1,0;MQ0F=0 PL 0,6,70 17 3994 . T <*> 0 . DP=2;I16=0,2,0,0,79,3125,0,0,120,7200,0,0,10,58,0,0;QS=1,0;MQ0F=0 PL 0,6,72 17 3995 . T <*> 0 . DP=2;I16=0,2,0,0,76,2890,0,0,120,7200,0,0,8,40,0,0;QS=1,0;MQ0F=0 PL 0,6,69 17 3996 . A <*> 0 . DP=2;I16=0,2,0,0,80,3218,0,0,120,7200,0,0,6,26,0,0;QS=1,0;MQ0F=0 PL 0,6,73 17 3997 . G <*> 0 . DP=2;I16=0,2,0,0,67,2257,0,0,120,7200,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,6,61 17 3998 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 3999 . G <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,38 17 4000 . C <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,36 17 4001 . T <*> 0 . 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INFO FORMAT HG00100 HG00101 HG00102 17 100 . C <*> 0 . DP=18;I16=16,1,0,0,672,27586,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,118:3:0 0,15,134:5:0 17 101 . C <*> 0 . DP=18;I16=16,1,0,0,630,24730,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,108:3:0 0,15,132:5:0 17 102 . C <*> 0 . DP=18;I16=16,1,0,0,676,27812,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,121:3:0 0,15,139:5:0 17 103 . T C,<*> 0 . DP=18;I16=15,1,1,0,668,28542,6,36,929,54841,29,841,323,7035,6,36;QS=2.98256,0.0174419,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64924;SCBZ=4;MQ0F=0 PL:DP:DV 0,17,184,24,187,185:9:1 0,9,118,9,118,118:3:0 0,15,147,15,147,147:5:0 17 104 . G C,<*> 0 . DP=18;I16=15,1,1,0,601,24163,3,9,929,54841,29,841,320,6884,7,49;QS=2.98726,0.0127389,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64309;SCBZ=4;MQ0F=0 PL:DP:DV 0,18,173,24,176,173:9:1 0,9,101,9,101,101:3:0 0,15,133,15,133,133:5:0 17 105 . G <*> 0 . DP=19;I16=17,1,0,0,603,22351,0,0,1018,59282,0,0,325,6815,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,171:10:0 0,9,106:3:0 0,15,125:5:0 17 106 . G <*> 0 . DP=19;I16=17,1,0,0,636,25058,0,0,1018,59282,0,0,324,6718,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,9,92:3:0 0,15,124:5:0 17 107 . C <*> 0 . DP=19;I16=17,1,0,0,686,27952,0,0,1018,59282,0,0,323,6643,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,192:10:0 0,9,119:3:0 0,15,136:5:0 17 108 . C <*> 0 . DP=19;I16=17,1,0,0,681,27429,0,0,1018,59282,0,0,322,6590,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,9,119:3:0 0,15,135:5:0 17 109 . T C,<*> 0 . DP=19;I16=16,1,1,0,716,30648,2,4,989,58441,29,841,309,6415,12,144;QS=2.98922,0.0107817,0;SGB=-0.556633;RPBZ=-0.674966;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.6661;SCBZ=3;MQ0F=0 PL:DP:DV 0,20,191,27,194,191:10:1 0,9,120,9,120,120:3:0 0,15,150,15,150,150:5:0 17 110 . G <*> 0 . DP=19;I16=17,1,0,0,688,28036,0,0,1018,59282,0,0,320,6550,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,194:10:0 0,9,113:3:0 0,15,136:5:0 17 111 . G <*> 0 . DP=19;I16=17,1,0,0,573,21453,0,0,1018,59282,0,0,318,6514,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,9,95:3:0 0,15,119:5:0 17 112 . C G,<*> 0 . DP=19;I16=16,1,1,0,657,26565,2,4,989,58441,29,841,301,6277,15,225;QS=2.98907,0.010929,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65292;SCBZ=3;MQ0F=0 PL:DP:DV 0,20,187,27,190,187:10:1 0,9,103,9,103,103:3:0 0,15,135,15,135,135:5:0 17 113 . A G,<*> 0 . DP=19;I16=16,1,1,0,635,25055,4,16,989,58441,29,841,297,6207,16,256;QS=2.98817,0.0118343,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65205;SCBZ=3;MQ0F=0 PL:DP:DV 0,20,172,27,175,172:10:1 0,9,102,9,102,102:3:0 0,15,139,15,139,139:5:0 17 114 . C <*> 0 . DP=19;I16=17,1,0,0,660,25876,0,0,1018,59282,0,0,310,6446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,181:10:0 0,9,113:3:0 0,15,133:5:0 17 115 . C A,<*> 0 . DP=21;I16=17,2,1,0,688,27426,12,144,1078,62882,29,841,283,5827,25,625;QS=2.88785,0.11215,0;SGB=-0.556633;RPBZ=0.260329;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.47798;SCBZ=-0.418446;MQ0F=0 PL:DP:DV 0,30,189,30,189,189:10:0 3,0,86,9,89,93:3:1 0,21,153,21,153,153:7:0 17 116 . A C,<*> 0 . DP=21;I16=17,2,1,0,705,27791,2,4,1078,62882,29,841,287,6073,19,361;QS=2.98873,0.0112676,0;SGB=-0.556633;RPBZ=0.0867763;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.65814;SCBZ=2.65016;MQ0F=0 PL:DP:DV 0,20,179,27,182,179:10:1 0,9,102,9,102,102:3:0 0,21,175,21,175,175:7:0 17 117 . G <*> 0 . DP=21;I16=18,2,0,0,715,28045,0,0,1107,63723,0,0,304,6444,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,185:10:0 0,9,97:3:0 0,21,177:7:0 17 118 . G <*> 0 . DP=20;I16=17,2,0,0,620,23470,0,0,1047,60123,0,0,303,6481,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,9,65:3:0 0,21,162:7:0 17 119 . G <*> 0 . DP=19;I16=16,2,0,0,619,23459,0,0,987,56523,0,0,301,6493,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,76:2:0 0,21,160:7:0 17 120 . A G,<*> 0 . DP=19;I16=15,2,1,0,646,25392,4,16,958,55682,29,841,277,5999,23,529;QS=2.9873,0.0126984,0;SGB=-0.556633;RPBZ=0.28942;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.6486;SCBZ=3;MQ0F=0 PL:DP:DV 0,18,171,24,174,171:9:1 0,6,88,6,88,88:2:0 0,21,171,21,171,171:7:0 17 121 . G <*> 0 . DP=19;I16=16,2,0,0,650,25148,0,0,987,56523,0,0,298,6534,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,181:9:0 0,6,84:2:0 0,21,168:7:0 17 122 . C <*> 0 . DP=20;I16=17,2,0,0,696,27784,0,0,1047,60123,0,0,296,6560,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,180:9:0 0,9,107:3:0 0,21,178:7:0 17 123 . T <*> 0 . DP=18;I16=15,2,0,0,647,26145,0,0,927,52923,0,0,296,6554,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,9,123:3:0 0,18,166:6:0 17 124 . T <*> 0 . DP=19;I16=16,2,0,0,606,22002,0,0,987,56523,0,0,296,6564,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,114:3:0 0,18,154:6:0 17 125 . A T,<*> 0 . DP=18;I16=14,2,1,0,589,22565,4,16,898,52082,29,841,272,5916,25,625;QS=2.98444,0.0155642,0;SGB=-0.556633;RPBZ=1.02125;MQBZ=-2.16025;MQSBZ=-1.23956;BQBZ=-1.64106;SCBZ=2.91548;MQ0F=0 PL:DP:DV 0,15,149,21,152,149:8:1 0,9,114,9,114,114:3:0 0,18,162,18,162,162:6:0 17 126 . A <*> 0 . DP=18;I16=15,2,0,0,629,24725,0,0,927,52923,0,0,298,6536,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,117:3:0 0,18,174:6:0 17 127 . C <*> 0 . DP=18;I16=15,2,0,0,627,24331,0,0,927,52923,0,0,299,6549,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,119:3:0 0,18,160:6:0 17 128 . A <*> 0 . DP=18;I16=15,2,0,0,660,26364,0,0,927,52923,0,0,300,6580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,121:3:0 0,18,168:6:0 17 129 . A <*> 0 . DP=17;I16=14,2,0,0,627,25407,0,0,867,49323,0,0,302,6628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,124:3:0 0,15,159:5:0 17 130 . A <*> 0 . DP=17;I16=14,2,0,0,627,25419,0,0,867,49323,0,0,304,6692,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,124:3:0 0,15,152:5:0 17 131 . C <*> 0 . DP=16;I16=13,2,0,0,593,24003,0,0,838,48482,0,0,280,6096,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,120:3:0 0,15,147:5:0 17 132 . A <*> 0 . DP=16;I16=13,2,0,0,610,25250,0,0,838,48482,0,0,281,6139,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,120:3:0 0,15,151:5:0 17 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 17 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 17 135 . T <*> 0 . DP=15;I16=13,2,0,0,605,24553,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,159:5:0 17 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 17 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 17 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 17 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 17 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 17 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 17 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 17 143 . G <*> 0 . DP=14;I16=12,2,0,0,426,13778,0,0,778,44882,0,0,292,6648,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,15,102:5:0 17 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 17 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 17 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 17 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 17 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 17 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 17 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 17 151 . G <*> 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 17 152 . C <*> 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 17 153 . A <*> 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 17 154 . T <*> 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 17 155 . C <*> 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 17 156 . C <*> 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 17 157 . C <*> 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 17 158 . T <*> 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 17 159 . A G,<*> 0 . DP=15;I16=12,2,1,0,519,19467,5,25,809,47641,60,3600,260,5880,0,0;QS=2.97076,0.0292398,0;SGB=-0.556633;RPBZ=-1.62019;MQBZ=0.267261;MQSBZ=-2.54951;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:DV 0,21,157,21,157,157:7:0 0,6,83,6,83,83:2:0 0,10,129,15,132,129:6:1 17 160 . G <*> 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 17 161 . A <*> 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 17 162 . A <*> 0 . DP=15;I16=13,2,0,0,558,21206,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 17 163 . G <*> 0 . DP=14;I16=12,2,0,0,505,18789,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,6,79:2:0 0,15,138:5:0 17 164 . T <*> 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 17 165 . G <*> 0 . DP=14;I16=12,2,0,0,473,17609,0,0,809,47641,0,0,252,5720,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,18,127:6:0 17 166 . A <*> 0 . DP=14;I16=12,2,0,0,502,19174,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,149:6:0 17 167 . A <*> 0 . DP=14;I16=12,2,0,0,486,17932,0,0,809,47641,0,0,252,5696,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,18,148:6:0 17 168 . G <*> 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 17 169 . C <*> 0 . DP=13;I16=11,2,0,0,408,14260,0,0,749,44041,0,0,252,5670,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,18,145:6:0 17 170 . C <*> 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 17 171 . A <*> 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 17 172 . C <*> 0 . DP=13;I16=11,2,0,0,451,16539,0,0,749,44041,0,0,249,5505,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,18,133:6:0 17 173 . C <*> 0 . DP=13;I16=11,2,0,0,437,15357,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,78:2:0 0,18,146:6:0 17 174 . G <*> 0 . DP=13;I16=12,1,0,0,356,10710,0,0,749,44041,0,0,248,5464,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,21,116:7:0 17 175 . C <*> 0 . DP=14;I16=13,1,0,0,515,19433,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,3,41:1:0 0,21,175:7:0 17 176 . C <*> 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 17 177 . C <*> 0 . DP=14;I16=13,1,0,0,490,17476,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,139:6:0 0,3,44:1:0 0,21,158:7:0 17 178 . A <*> 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 17 179 . A <*> 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 17 180 . A <*> 0 . DP=14;I16=13,1,0,0,432,14702,0,0,809,47641,0,0,256,5534,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,21,148:7:0 17 181 . G <*> 0 . DP=14;I16=13,1,0,0,469,17345,0,0,809,47641,0,0,257,5571,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,21,142:7:0 17 182 . A <*> 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 17 183 . C <*> 0 . DP=15;I16=14,1,0,0,491,17483,0,0,869,51241,0,0,260,5688,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,21,140:7:0 17 184 . A <*> 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 17 185 . C <*> 0 . DP=15;I16=14,1,0,0,499,17439,0,0,869,51241,0,0,263,5817,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,21,161:7:0 17 186 . G <*> 0 . DP=15;I16=14,1,0,0,393,11519,0,0,869,51241,0,0,264,5878,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,118:7:0 0,3,32:1:0 0,21,123:7:0 17 187 . C <*> 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 17 188 . C <*> 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 17 189 . C <*> 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 17 190 . A C,<*> 0 . DP=15;I16=12,2,1,0,500,18230,5,25,778,44882,60,3600,243,5381,25,625;QS=2.97664,0.0233645,0;SGB=-0.556633;RPBZ=0;MQBZ=0.392232;MQSBZ=-3.74166;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:DV 0,18,138,18,138,138:6:0 0,6,68,6,68,68:2:0 0,12,153,18,156,153:7:1 17 191 . T <*> 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 17 192 . G <*> 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 17 193 . T <*> 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 17 194 . C <*> 0 . DP=14;I16=12,2,0,0,471,16817,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,144:6:0 0,6,67:2:0 0,18,145:6:0 17 195 . C <*> 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 17 196 . A <*> 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 17 197 . G <*> 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 17 198 . C <*> 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 17 199 . T <*> 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 17 200 . T <*> 0 . DP=15;I16=11,4,0,0,545,19991,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 17 201 . A <*> 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 17 202 . A <*> 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 17 203 . C <*> 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 17 204 . C <*> 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 17 205 . T <*> 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 17 206 . G <*> 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 17 207 . C <*> 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 17 208 . A <*> 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 17 209 . T <*> 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 17 210 . C <*> 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 17 211 . C <*> 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 17 212 . C <*> 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 17 213 . T <*> 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 17 214 . A <*> 0 . DP=16;I16=12,4,0,0,539,19501,0,0,836,46564,0,0,262,5732,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,18,120:6:0 17 215 . G <*> 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 17 216 . A <*> 0 . DP=14;I16=11,3,0,0,473,16981,0,0,747,42123,0,0,263,5791,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,12,85:4:0 17 217 . A <*> 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 17 218 . G <*> 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 17 219 . T <*> 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 17 220 . G <*> 0 . DP=14;I16=11,3,0,0,495,18407,0,0,747,42123,0,0,267,6079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,12,84:4:0 17 221 . A <*> 0 . DP=14;I16=11,3,0,0,488,17688,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,89:3:0 0,12,101:4:0 17 222 . A <*> 0 . DP=14;I16=11,3,0,0,479,17747,0,0,747,42123,0,0,267,6203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,89:3:0 0,12,73:4:0 17 223 . G T,<*> 0 . DP=13;I16=9,3,1,0,412,14782,8,64,627,34923,60,3600,243,5657,25,625;QS=2.96596,0.0340426,0;SGB=-0.556633;RPBZ=1.07052;MQBZ=0.547723;MQSBZ=-3.4641;BQBZ=-1.60577;SCBZ=0;MQ0F=0 PL:DP:DV 0,11,166,18,169,167:7:1 0,6,53,6,53,53:2:0 0,12,81,12,81,81:4:0 17 224 . G <*> 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 17 225 . C <*> 0 . DP=12;I16=9,3,0,0,390,13960,0,0,627,34923,0,0,272,6466,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,12,86:4:0 17 226 . A G,C,<*> 0 . DP=13;I16=8,3,1,1,381,13669,6,18,567,31323,89,4441,248,5894,44,986;QS=2.94293,0.0392157,0.0178571,0;VDB=0.84;SGB=-2.62246;RPBZ=-0.592157;MQBZ=-0.615457;MQSBZ=-3.4641;BQBZ=-2.17723;SCBZ=2.34521;MQ0F=0 PL:DP:DV 0,18,159,12,162,159,18,159,162,159:7:1 0,6,53,6,53,53,6,53,53,53:2:0 0,5,79,9,82,80,9,82,80,80:4:1 17 227 . C <*> 0 . DP=13;I16=9,4,0,0,412,14342,0,0,656,35764,0,0,292,6878,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,12,75:4:0 17 228 . C <*> 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 17 229 . G <*> 0 . DP=13;I16=9,4,0,0,368,11524,0,0,656,35764,0,0,292,6898,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,145:7:0 0,6,53:2:0 0,12,70:4:0 17 230 . C <*> 0 . DP=13;I16=9,4,0,0,460,16788,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,99:4:0 17 231 . C <*> 0 . DP=13;I16=9,4,0,0,428,15932,0,0,656,35764,0,0,292,6950,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,12,83:4:0 17 232 . C <*> 0 . DP=14;I16=10,4,0,0,474,17240,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,6,53:2:0 0,15,101:5:0 17 233 . A <*> 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 17 234 . A <*> 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 17 235 . A <*> 0 . DP=14;I16=10,4,0,0,488,17796,0,0,716,39364,0,0,291,6951,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,15,115:5:0 17 236 . G <*> 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 17 237 . A C,<*> 0 . DP=14;I16=9,4,1,0,465,16877,8,64,656,35764,60,3600,266,6282,25,625;QS=2.93162,0.0683761,0;SGB=-0.556633;RPBZ=1.11754;MQBZ=0.632456;MQSBZ=-3.60555;BQBZ=-1.61959;SCBZ=-0.27735;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,53,6,53,53:2:0 0,3,84,9,87,87:4:1 17 238 . C <*> 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 17 239 . A <*> 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 17 240 . C <*> 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 17 241 . G <*> 0 . DP=15;I16=10,5,0,0,456,14780,0,0,776,42964,0,0,292,6688,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,12,64:4:0 17 242 . C <*> 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 17 243 . C <*> 0 . DP=16;I16=10,6,0,0,531,19777,0,0,805,43805,0,0,297,6597,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,219:9:0 0,9,54:3:0 0,12,104:4:0 17 244 . C <*> 0 . DP=16;I16=10,6,0,0,611,23627,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,72:3:0 0,12,106:4:0 17 245 . A <*> 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 17 246 . T <*> 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 17 247 . G <*> 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 17 248 . T <*> 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 17 249 . C <*> 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 17 250 . C <*> 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 17 251 . A <*> 0 . DP=19;I16=10,9,0,0,697,26587,0,0,923,49087,0,0,313,6627,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,97:4:0 0,15,148:5:0 17 252 . G <*> 0 . DP=18;I16=9,9,0,0,652,24752,0,0,863,45487,0,0,316,6646,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,15,126:5:0 17 253 . C <*> 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 17 254 . T <*> 0 . DP=20;I16=10,10,0,0,731,27661,0,0,952,49928,0,0,323,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,78:4:0 0,18,164:6:0 17 255 . T <*> 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 17 256 . A <*> 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 17 257 . T <*> 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 17 258 . T <*> 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 17 259 . C <*> 0 . DP=22;I16=11,11,0,0,793,29873,0,0,1049,54897,0,0,353,7377,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,92:5:0 0,18,170:6:0 17 260 . T <*> 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 17 261 . G <*> 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 17 262 . C <*> 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 17 263 . C <*> 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 17 264 . C <*> 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 17 265 . A <*> 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 17 266 . G <*> 0 . DP=21;I16=9,12,0,0,754,28204,0,0,989,51297,0,0,394,8458,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,15,138:5:0 17 267 . T G,<*> 0 . DP=21;I16=9,11,0,1,739,27465,8,64,960,50456,29,841,373,7935,25,625;QS=2.94203,0.057971,0;SGB=-0.556633;RPBZ=-0.330396;MQBZ=-1.23153;MQSBZ=-3.3021;BQBZ=-1.66282;SCBZ=2.91633;MQ0F=0 PL:DP:DV 0,33,254,33,254,254:11:0 0,6,93,12,96,96:5:1 0,15,149,15,149,149:5:0 17 268 . T <*> 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 17 269 . C <*> 0 . DP=22;I16=9,13,0,0,767,28641,0,0,1018,52138,0,0,406,8836,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,91:5:0 0,15,154:5:0 17 270 . C <*> 0 . DP=22;I16=9,13,0,0,766,28210,0,0,1018,52138,0,0,410,8962,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,98:5:0 0,15,143:5:0 17 271 . T <*> 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 17 272 . C <*> 0 . DP=22;I16=9,13,0,0,815,31449,0,0,1018,52138,0,0,415,9143,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,97:5:0 0,15,149:5:0 17 273 . T C,<*> 0 . DP=22;I16=9,12,0,1,798,30664,5,25,989,51297,29,841,392,8620,25,625;QS=2.96094,0.0390625,0;SGB=-0.556633;RPBZ=-0.236567;MQBZ=-1.16701;MQSBZ=-3.42286;BQBZ=-1.66779;SCBZ=3.00076;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,7,89,12,92,90:5:1 0,15,161,15,161,161:5:0 17 274 . C <*> 0 . DP=22;I16=9,13,0,0,767,28193,0,0,1018,52138,0,0,419,9371,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,101:5:0 0,15,144:5:0 17 275 . C <*> 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 17 276 . A <*> 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 17 277 . G <*> 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 17 278 . A C,<*> 0 . DP=21;I16=6,14,1,0,722,26452,7,49,867,42179,60,3600,415,9521,11,121;QS=2.97935,0.020649,0;SGB=-0.556633;RPBZ=1.65198;MQBZ=1.0247;MQSBZ=-3.24037;BQBZ=-1.66667;SCBZ=-0.324037;MQ0F=0 PL:DP:DV 0,22,231,30,234,231:11:1 0,18,123,18,123,123:6:0 0,12,121,12,121,121:4:0 17 279 . A <*> 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 17 280 . A <*> 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 17 281 . G <*> 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 17 282 . G <*> 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 17 283 . C <*> 0 . DP=23;I16=7,16,0,0,829,31789,0,0,1016,50220,0,0,431,9599,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,15,122:5:0 17 284 . T <*> 0 . DP=23;I16=7,16,0,0,895,35059,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,138:5:0 17 285 . G <*> 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 17 286 . C <*> 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 17 287 . A <*> 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 17 288 . T <*> 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 17 289 . G <*> 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 17 290 . G <*> 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 17 291 . T <*> 0 . DP=24;I16=8,16,0,0,850,31716,0,0,1107,56579,0,0,434,9648,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,18,138:6:0 17 292 . T <*> 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 17 293 . G <*> 0 . DP=26;I16=10,16,0,0,946,35376,0,0,1227,63779,0,0,439,9713,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,18,148:6:0 17 294 . A <*> 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 17 295 . C <*> 0 . DP=25;I16=10,15,0,0,909,34117,0,0,1198,62938,0,0,447,9833,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,183:8:0 0,18,159:6:0 17 296 . A <*> 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 17 297 . C G,<*> 0 . DP=25;I16=9,15,1,0,901,34305,4,16,1138,59338,60,3600,445,9901,10,100;QS=2.98261,0.0173913,0;SGB=-0.556633;RPBZ=-1.24856;MQBZ=0.806872;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.368383;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 0,15,168,21,171,168:8:1 0,18,161,18,161,161:6:0 17 298 . A <*> 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 17 299 . C <*> 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 17 300 . A <*> 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 17 301 . G <*> 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 17 302 . T <*> 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,240,9600,760,30400,236,10564,993,55133,109,2229,377,8629;QS=0.539485,2.46052;VDB=0.241622;SGB=-4.22417;RPBZ=1.11989;MQBZ=1.47646;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.268121;MQ0F=0 PL:DP:DV 161,0,99:11:6 158,0,14:7:6 201,21,0:7:7 17 303 . G <*> 0 . DP=25;I16=10,15,0,0,968,37972,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 17 304 . C <*> 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 17 305 . C <*> 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 17 306 . T <*> 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 17 307 . G <*> 0 . DP=27;I16=11,16,0,0,989,37911,0,0,1318,70138,0,0,523,11823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,189:8:0 0,24,203:8:0 17 308 . C <*> 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 17 309 . G <*> 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 17 310 . A <*> 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 17 311 . C <*> 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 17 312 . A <*> 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 17 313 . A <*> 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 17 314 . A <*> 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 17 315 . G <*> 0 . DP=26;I16=10,16,0,0,1023,40789,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 17 316 . C <*> 0 . DP=27;I16=10,17,0,0,992,39446,0,0,1349,72897,0,0,564,12918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,184:9:0 0,24,224:8:0 17 317 . T <*> 0 . DP=27;I16=10,17,0,0,1025,40437,0,0,1349,72897,0,0,567,12957,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,229:9:0 0,24,206:8:0 17 318 . G <*> 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 17 319 . A <*> 0 . DP=27;I16=10,17,0,0,1005,38775,0,0,1349,72897,0,0,572,13050,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,24,196:8:0 17 320 . A <*> 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 17 321 . T <*> 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 17 322 . G <*> 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 17 323 . C <*> 0 . DP=28;I16=10,18,0,0,1076,42700,0,0,1409,76497,0,0,573,13003,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,27,208:9:0 17 324 . T <*> 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 17 325 . A <*> 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 17 326 . T <*> 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 17 327 . C <*> 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 17 328 . A <*> 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 17 329 . T <*> 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 17 330 . T <*> 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 17 331 . T <*> 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 17 332 . A <*> 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 17 333 . A <*> 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 17 334 . A <*> 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 17 335 . A G,<*> 0 . DP=32;I16=13,18,1,0,1084,40336,4,16,1589,87297,60,3600,555,11943,0,0;QS=2.98919,0.0108108,0;SGB=-0.556633;RPBZ=-1.67936;MQBZ=0.622171;MQSBZ=-2.25492;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:DV 0,33,252,33,252,252:11:0 0,27,219,27,219,219:9:0 0,25,245,33,248,245:12:1 17 336 . A <*> 0 . DP=32;I16=14,18,0,0,1094,39794,0,0,1649,90897,0,0,555,11935,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,36,255:12:0 17 337 . C A,<*> 0 . DP=32;I16=14,17,0,1,1125,42481,5,25,1612,89528,37,1369,536,11590,18,324;QS=2.98113,0.0188679,0;SGB=-0.556633;RPBZ=0.812593;MQBZ=-1.03695;MQSBZ=-2.25492;BQBZ=-1.68353;SCBZ=-0.258065;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 0,17,195,24,198,195:9:1 0,36,255,36,255,255:12:0 17 338 . T <*> 0 . DP=30;I16=14,16,0,0,1190,47898,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 17 339 . C <*> 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 17 340 . C <*> 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 17 341 . T <*> 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 17 342 . T <*> 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 17 343 . G <*> 0 . DP=32;I16=14,18,0,0,1157,43751,0,0,1649,90897,0,0,554,11978,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,218:9:0 0,36,255:12:0 17 344 . C <*> 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 17 345 . T <*> 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 17 346 . G <*> 0 . DP=31;I16=15,16,0,0,1142,43222,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 17 347 . G <*> 0 . DP=31;I16=15,16,0,0,1124,42252,0,0,1620,90056,0,0,560,12414,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,24,207:8:0 0,36,255:12:0 17 348 . T <*> 0 . DP=32;I16=16,16,0,0,1149,43023,0,0,1680,93656,0,0,562,12556,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,27,228:9:0 0,36,255:12:0 17 349 . T <*> 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 17 350 . T <*> 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 17 351 . G <*> 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 17 352 . A <*> 0 . DP=31;I16=16,15,0,0,1162,45664,0,0,1651,92815,0,0,569,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,33,255:11:0 17 353 . G <*> 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 17 354 . A <*> 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 17 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPBZ=0.185772;MQBZ=0.520126;MQSBZ=-1.7696;BQBZ=0.683978;SCBZ=-0.27735;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 17 356 . G <*> 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 17 357 . C <*> 0 . DP=28;I16=15,13,0,0,1026,39496,0,0,1525,87005,0,0,575,13209,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,30,252:10:0 17 358 . A <*> 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 17 359 . G T,<*> 0 . DP=29;I16=15,13,0,1,1085,42761,10,100,1525,87005,60,3600,552,12620,25,625;QS=2.96032,0.0396825,0;SGB=-0.556633;RPBZ=-0.119611;MQBZ=0.456435;MQSBZ=-1.53333;BQBZ=-1.68246;SCBZ=5.2915;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,13,178,21,181,180:8:1 0,33,255,33,255,255:11:0 17 360 . A <*> 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 17 361 . A <*> 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 17 362 . A <*> 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 17 363 . A <*> 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 17 364 . T <*> 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 17 365 . G <*> 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 17 366 . A <*> 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 17 367 . T <*> 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 17 368 . A <*> 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 17 369 . T G,<*> 0 . DP=28;I16=16,11,0,1,1037,40275,6,36,1496,86164,60,3600,548,12256,25,625;QS=2.97683,0.023166,0;SGB=-0.556633;RPBZ=0.12395;MQBZ=0.408248;MQSBZ=-1.37784;BQBZ=-1.68703;SCBZ=5.19615;MQ0F=0 PL:DP:DV 0,30,250,30,250,250:10:0 0,15,189,21,192,190:8:1 0,30,255,30,255,255:10:0 17 370 . C <*> 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 17 371 . T <*> 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 17 372 . C <*> 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 17 373 . A <*> 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 17 374 . T <*> 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 17 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPBZ=-1.45432;MQBZ=0.3849;MQSBZ=-1.26404;BQBZ=-1.68488;SCBZ=0;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 17 376 . G <*> 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 17 377 . T <*> 0 . DP=31;I16=17,14,0,0,1116,41750,0,0,1736,100564,0,0,543,11985,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,211:8:0 0,33,255:11:0 17 378 . T <*> 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 17 379 . G <*> 0 . DP=29;I16=18,11,0,0,1060,40230,0,0,1678,98882,0,0,541,11897,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,187:7:0 0,30,255:10:0 17 380 . C <*> 0 . DP=29;I16=18,11,0,0,1094,42792,0,0,1678,98882,0,0,539,11797,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,30,255:10:0 17 381 . T <*> 0 . DP=29;I16=18,11,0,0,1167,47337,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,211:7:0 0,30,255:10:0 17 382 . T <*> 0 . DP=29;I16=18,11,0,0,1062,40514,0,0,1678,98882,0,0,535,11693,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,182:7:0 0,30,255:10:0 17 383 . T <*> 0 . DP=29;I16=18,11,0,0,1059,39847,0,0,1678,98882,0,0,532,11638,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,172:7:0 0,30,255:10:0 17 384 . A C,<*> 0 . DP=31;I16=19,11,0,1,1077,39885,4,16,1738,102482,60,3600,504,10988,25,625;QS=2.98419,0.0158103,0;SGB=-0.556633;RPBZ=0.615229;MQBZ=0.262613;MQSBZ=-0.333409;BQBZ=-1.68746;SCBZ=0;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,15,171,21,174,171:8:1 0,30,255,30,255,255:10:0 17 385 . C <*> 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 17 386 . T <*> 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 17 387 . T <*> 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 17 388 . T <*> 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 17 389 . G <*> 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 17 390 . C <*> 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 17 391 . A <*> 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 17 392 . T <*> 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 17 393 . A <*> 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 17 394 . T <*> 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 17 395 . T <*> 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 17 396 . T <*> 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 17 397 . T <*> 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 17 398 . A <*> 0 . DP=28;I16=17,11,0,0,1025,38361,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 17 399 . A <*> 0 . DP=28;I16=17,11,0,0,1023,38949,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 17 400 . A <*> 0 . DP=29;I16=17,12,0,0,1070,40554,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 17 401 . A C,<*> 0 . DP=29;I16=17,11,0,1,1063,41001,8,64,1587,92523,60,3600,501,11113,25,625;QS=2.97985,0.0201511,0;SGB=-0.556633;RPBZ=-0.478622;MQBZ=0.339683;MQSBZ=0.29364;BQBZ=-1.68267;SCBZ=0;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,15,160,15,160,160:5:0 0,22,255,30,255,255:11:1 17 402 . T <*> 0 . DP=29;I16=17,12,0,0,1076,40740,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 17 403 . T <*> 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 17 404 . G <*> 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 17 405 . T <*> 0 . DP=27;I16=16,11,0,0,997,37951,0,0,1558,91682,0,0,526,11592,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,30,255:10:0 17 406 . G <*> 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 17 407 . A <*> 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 17 408 . C <*> 0 . DP=28;I16=16,12,0,0,1013,38245,0,0,1618,95282,0,0,525,11505,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,30,244:10:0 17 409 . T <*> 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 17 410 . T <*> 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 17 411 . T <*> 0 . DP=29;I16=17,12,0,0,1022,37928,0,0,1678,98882,0,0,522,11342,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,111:4:0 0,33,255:11:0 17 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPBZ=-0.40473;MQBZ=0.267261;MQSBZ=-0.293785;BQBZ=-1.6942;SCBZ=0;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 17 413 . A <*> 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 17 414 . T <*> 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 17 415 . G <*> 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 17 416 . G <*> 0 . DP=30;I16=18,12,0,0,1089,41309,0,0,1738,102482,0,0,529,11381,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,33,252:11:0 17 417 . C <*> 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 17 418 . A <*> 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 17 419 . T <*> 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 17 420 . A <*> 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 17 421 . A <*> 0 . DP=33;I16=19,14,0,0,1211,45581,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 17 422 . A <*> 0 . DP=33;I16=19,14,0,0,1221,46833,0,0,1887,110523,0,0,535,11707,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,42,255:14:0 17 423 . T <*> 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 17 424 . A <*> 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 17 425 . A <*> 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 17 426 . T <*> 0 . DP=29;I16=16,13,0,0,1005,36625,0,0,1647,96123,0,0,544,11912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,33,227:11:0 17 427 . A <*> 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 17 428 . C <*> 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 17 429 . T <*> 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 17 430 . G <*> 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 17 431 . G <*> 0 . DP=30;I16=16,14,0,0,1012,37006,0,0,1707,99723,0,0,553,12255,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,33,224:11:0 17 432 . T <*> 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 17 433 . T <*> 0 . DP=28;I16=14,14,0,0,969,35651,0,0,1587,92523,0,0,559,12467,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,30,229:10:0 17 434 . T <*> 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 17 435 . A <*> 0 . DP=29;I16=15,14,0,0,1035,38091,0,0,1647,96123,0,0,562,12596,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,30,237:10:0 17 436 . T <*> 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 17 437 . T G,<*> 0 . DP=28;I16=13,14,1,0,990,36832,6,36,1558,91682,29,841,549,12435,16,256;QS=2.9781,0.0218978,0;SGB=-0.556633;RPBZ=-1.36214;MQBZ=-2.88675;MQSBZ=0.6;BQBZ=-1.67909;SCBZ=0;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,109,9,109,109:3:0 0,17,200,24,203,201:9:1 17 438 . A <*> 0 . DP=28;I16=14,14,0,0,984,35784,0,0,1587,92523,0,0,565,12707,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,220:9:0 17 439 . C <*> 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 17 440 . A <*> 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 17 441 . G <*> 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 17 442 . A <*> 0 . DP=29;I16=15,14,0,0,1079,40643,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,27,233:9:0 17 443 . A <*> 0 . DP=30;I16=14,15,0,0,1153,46639,0,0,1647,96123,0,0,532,12036,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,130:3:0 0,27,246:9:0 17 444 . G <*> 0 . DP=29;I16=14,14,0,0,1083,43077,0,0,1587,92523,0,0,533,12103,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,98:2:0 0,27,227:9:0 17 445 . C <*> 0 . DP=30;I16=15,14,0,0,1090,42406,0,0,1647,96123,0,0,534,12196,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,122:3:0 0,27,219:9:0 17 446 . A <*> 0 . DP=30;I16=15,14,0,0,1092,42240,0,0,1647,96123,0,0,535,12265,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,127:3:0 0,27,232:9:0 17 447 . C <*> 0 . DP=29;I16=15,13,0,0,1095,43635,0,0,1618,95282,0,0,534,12208,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,125:3:0 0,27,235:9:0 17 448 . T <*> 0 . DP=29;I16=15,13,0,0,1104,44276,0,0,1618,95282,0,0,533,12173,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,130:3:0 0,27,240:9:0 17 449 . A <*> 0 . DP=28;I16=14,13,0,0,1071,43181,0,0,1558,91682,0,0,533,12159,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,97:2:0 0,27,245:9:0 17 450 . G <*> 0 . DP=28;I16=14,13,0,0,1053,42427,0,0,1558,91682,0,0,533,12165,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,98:2:0 0,27,233:9:0 17 451 . A <*> 0 . DP=28;I16=14,13,0,0,1003,38887,0,0,1558,91682,0,0,533,12191,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,100:2:0 0,27,244:9:0 17 452 . A <*> 0 . DP=31;I16=17,13,0,0,1071,40901,0,0,1738,102482,0,0,533,12237,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,121:3:0 0,27,225:9:0 17 453 . A <*> 0 . DP=31;I16=17,13,0,0,1057,40647,0,0,1738,102482,0,0,536,12306,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,129:3:0 0,27,225:9:0 17 454 . A <*> 0 . DP=31;I16=17,13,0,0,1156,45762,0,0,1738,102482,0,0,540,12400,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,130:3:0 0,30,255:10:0 17 455 . T <*> 0 . DP=32;I16=17,14,0,0,1140,43710,0,0,1775,103851,0,0,543,12419,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,124:3:0 0,33,255:11:0 17 456 . G <*> 0 . DP=32;I16=17,14,0,0,1154,44790,0,0,1775,103851,0,0,547,12465,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,128:3:0 0,33,250:11:0 17 457 . C <*> 0 . DP=33;I16=18,14,0,0,1205,46913,0,0,1835,107451,0,0,552,12538,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,131:3:0 0,33,255:11:0 17 458 . A <*> 0 . DP=33;I16=18,14,0,0,1208,46550,0,0,1835,107451,0,0,558,12590,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,122:3:0 0,33,255:11:0 17 459 . T <*> 0 . DP=33;I16=18,14,0,0,1153,43773,0,0,1835,107451,0,0,563,12625,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,105:3:0 0,33,255:11:0 17 460 . G <*> 0 . DP=32;I16=18,13,0,0,1199,47305,0,0,1775,103851,0,0,568,12642,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,128:3:0 0,30,255:10:0 17 461 . T <*> 0 . DP=32;I16=18,13,0,0,1194,47178,0,0,1775,103851,0,0,572,12640,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,127:3:0 0,30,255:10:0 17 462 . G <*> 0 . DP=32;I16=18,13,0,0,1169,46001,0,0,1775,103851,0,0,577,12669,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,30,241:10:0 17 463 . G <*> 0 . DP=32;I16=18,13,0,0,1095,41573,0,0,1775,103851,0,0,583,12729,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,126:4:0 0,30,221:10:0 17 464 . A <*> 0 . DP=32;I16=18,13,0,0,1100,41724,0,0,1775,103851,0,0,589,12821,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,148:4:0 0,30,217:10:0 17 465 . C T,<*> 0 . DP=33;I16=19,12,0,1,1173,45601,4,16,1775,103851,60,3600,589,12909,6,36;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.67982;MQBZ=0.321288;MQSBZ=0.341466;BQBZ=-1.68493;SCBZ=0;MQ0F=0 PL:DP:DV 0,51,255,51,255,255:17:0 0,15,158,15,158,158:5:0 0,20,224,27,227,224:10:1 17 466 . A <*> 0 . DP=34;I16=20,13,0,0,1268,49686,0,0,1895,111051,0,0,602,13102,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,173:5:0 0,30,255:10:0 17 467 . A <*> 0 . DP=34;I16=20,13,0,0,1246,48610,0,0,1895,111051,0,0,608,13194,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,177:5:0 0,30,251:10:0 17 468 . A <*> 0 . DP=35;I16=21,13,0,0,1253,48095,0,0,1955,114651,0,0,613,13273,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,174:5:0 0,30,251:10:0 17 469 . A <*> 0 . DP=35;I16=21,13,0,0,1260,49028,0,0,1955,114651,0,0,618,13340,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,30,255:10:0 17 470 . G <*> 0 . DP=35;I16=21,13,0,0,1265,48879,0,0,1955,114651,0,0,623,13445,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,167:5:0 0,30,238:10:0 17 471 . T G,C,<*> 0 . DP=36;I16=21,12,0,2,1220,46380,18,162,1918,113282,97,4969,611,13281,16,256;QS=2.94529,0.0273556,0.0273556,0;VDB=0.96;SGB=0.346553;RPBZ=0.497712;MQBZ=-1.9761;MQSBZ=0.312094;BQBZ=-2.35032;SCBZ=0;MQ0F=0 PL:DP:DV 0,57,255,57,255,255,57,255,255,255:19:0 0,15,169,15,169,169,15,169,169,169:5:0 0,19,219,19,221,219,27,222,222,221:11:2 17 472 . T <*> 0 . DP=35;I16=21,13,0,0,1234,46640,0,0,1955,114651,0,0,633,13665,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,172:5:0 0,30,241:10:0 17 473 . G <*> 0 . DP=35;I16=21,13,0,0,1303,51953,0,0,1955,114651,0,0,638,13780,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,159:5:0 0,30,250:10:0 17 474 . G <*> 0 . DP=36;I16=22,13,0,0,1279,49235,0,0,2015,118251,0,0,642,13884,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,33,255:11:0 17 475 . G <*> 0 . DP=36;I16=22,13,0,0,1299,49939,0,0,2015,118251,0,0,647,14029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,159:5:0 0,33,253:11:0 17 476 . A <*> 0 . DP=36;I16=22,13,0,0,1298,50202,0,0,2015,118251,0,0,651,14167,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,177:5:0 0,33,255:11:0 17 477 . T <*> 0 . DP=36;I16=22,13,0,0,1301,50339,0,0,2015,118251,0,0,655,14349,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,167:5:0 0,33,255:11:0 17 478 . T <*> 0 . DP=38;I16=24,13,0,0,1318,48974,0,0,2135,125451,0,0,656,14422,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,174:6:0 0,33,255:11:0 17 479 . A <*> 0 . DP=38;I16=24,13,0,0,1397,54499,0,0,2135,125451,0,0,659,14535,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,184:6:0 0,33,255:11:0 17 480 . G <*> 0 . DP=37;I16=24,12,0,0,1419,57531,0,0,2075,121851,0,0,662,14638,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,187:6:0 0,33,255:11:0 17 481 . G <*> 0 . DP=37;I16=24,12,0,0,1382,54524,0,0,2075,121851,0,0,664,14728,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,187:6:0 0,33,255:11:0 17 482 . A <*> 0 . DP=37;I16=24,12,0,0,1344,52614,0,0,2075,121851,0,0,666,14854,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,33,255:11:0 17 483 . G <*> 0 . DP=37;I16=23,13,0,0,1402,55722,0,0,2075,121851,0,0,666,14864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,187:6:0 0,33,255:11:0 17 484 . A <*> 0 . DP=36;I16=23,12,0,0,1329,52551,0,0,2015,118251,0,0,668,14906,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,33,255:11:0 17 485 . G <*> 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 17 486 . A <*> 0 . DP=34;I16=22,12,0,0,1313,51667,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 17 487 . G <*> 0 . DP=34;I16=22,12,0,0,1300,50304,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 17 488 . A G,<*> 0 . DP=35;I16=22,12,1,0,1278,48412,4,16,1986,117410,29,841,646,14380,25,625;QS=2.98947,0.0105263,0;SGB=-0.556633;RPBZ=0.594463;MQBZ=-3.36505;MQSBZ=0.10737;BQBZ=-1.69552;SCBZ=0;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,18,177,18,177,177:6:0 0,23,255,30,255,255:11:1 17 489 . A <*> 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 17 490 . A <*> 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 17 491 . T <*> 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 17 492 . G <*> 0 . DP=35;I16=23,12,0,0,1273,48547,0,0,2046,121010,0,0,671,15109,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,175:7:0 0,30,251:10:0 17 493 . A <*> 0 . DP=34;I16=22,12,0,0,1281,49545,0,0,1986,117410,0,0,672,15156,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,242:9:0 17 494 . A <*> 0 . DP=34;I16=22,12,0,0,1324,52440,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,27,255:9:0 17 495 . G <*> 0 . DP=34;I16=22,12,0,0,1265,48677,0,0,1986,117410,0,0,672,15236,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,170:7:0 0,27,244:9:0 17 496 . A <*> 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 17 497 . C <*> 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 17 498 . A <*> 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 17 499 . T <*> 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 17 500 . A <*> 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 17 501 . T <*> 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 17 502 . G <*> 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 17 503 . T <*> 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 17 504 . C <*> 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 17 505 . C <*> 0 . DP=35;I16=24,11,0,0,1217,44421,0,0,2046,121010,0,0,648,14558,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,189:7:0 0,27,221:9:0 17 506 . A <*> 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 17 507 . C <*> 0 . DP=35;I16=24,11,0,0,1231,45137,0,0,2046,121010,0,0,644,14482,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,183:7:0 0,27,226:9:0 17 508 . A <*> 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 17 509 . C <*> 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 17 510 . A <*> 0 . DP=34;I16=23,11,0,0,1211,44827,0,0,1986,117410,0,0,638,14398,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,187:7:0 0,24,221:8:0 17 511 . A <*> 0 . DP=34;I16=23,11,0,0,1238,46516,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 17 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1133,41513,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97766,0.0223368,0;SGB=-0.556633;RPBZ=-1.47079;MQBZ=0.253876;MQSBZ=-0.461593;BQBZ=-1.68442;SCBZ=0;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 17 513 . A T,<*> 0 . DP=32;I16=21,10,1,0,1125,42283,12,144,1806,106610,60,3600,623,14249,15,225;QS=2.97966,0.020339,0;SGB=-0.556633;RPBZ=-1.24609;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.57376;SCBZ=0;MQ0F=0 PL:DP:DV 0,37,255,48,255,255:17:1 0,21,177,21,177,177:7:0 0,24,233,24,233,233:8:0 17 514 . A T,<*> 0 . DP=32;I16=22,9,0,1,1086,40204,16,256,1806,106610,60,3600,627,14381,11,121;QS=2.97127,0.0287253,0;SGB=-0.556633;RPBZ=-1.4628;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.46657;SCBZ=0;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,21,172,21,172,172:7:0 0,24,235,24,235,235:8:0 17 515 . C <*> 0 . DP=32;I16=22,10,0,0,1050,37704,0,0,1866,110210,0,0,638,14554,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,211:8:0 17 516 . C <*> 0 . DP=32;I16=22,10,0,0,1109,40651,0,0,1866,110210,0,0,637,14579,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,24,215:8:0 17 517 . T <*> 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 17 518 . G <*> 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 17 519 . T <*> 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 17 520 . T <*> 0 . DP=36;I16=25,11,0,0,1243,45051,0,0,2106,124610,0,0,638,14818,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,180:7:0 0,24,223:8:0 17 521 . C <*> 0 . DP=34;I16=25,9,0,0,1281,49527,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 17 522 . A <*> 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 17 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPBZ=1.13742;MQBZ=0.179605;MQSBZ=-1.73205;BQBZ=-1.68805;SCBZ=0;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 17 524 . T <*> 0 . DP=32;I16=24,8,0,0,1096,39618,0,0,1897,112969,0,0,654,15108,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,15,150:5:0 17 525 . G <*> 0 . DP=32;I16=24,8,0,0,1188,45718,0,0,1897,112969,0,0,656,15120,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,15,133:5:0 17 526 . C <*> 0 . DP=32;I16=24,8,0,0,1154,44014,0,0,1897,112969,0,0,658,15156,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,137:5:0 17 527 . A <*> 0 . DP=33;I16=25,8,0,0,1220,46386,0,0,1957,116569,0,0,658,15118,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,18,181:6:0 17 528 . G <*> 0 . DP=33;I16=25,8,0,0,1268,49968,0,0,1957,116569,0,0,658,15060,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,172:7:0 0,18,193:6:0 17 529 . C <*> 0 . DP=32;I16=25,7,0,0,1158,44462,0,0,1897,112969,0,0,658,14982,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,187:7:0 0,18,184:6:0 17 530 . T <*> 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 17 531 . T <*> 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 17 532 . T <*> 0 . DP=32;I16=25,7,0,0,1161,43607,0,0,1897,112969,0,0,649,14477,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,192:6:0 17 533 . C <*> 0 . DP=32;I16=25,7,0,0,1154,44084,0,0,1897,112969,0,0,644,14274,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,178:7:0 0,18,180:6:0 17 534 . T <*> 0 . DP=31;I16=24,7,0,0,1222,49526,0,0,1837,109369,0,0,640,14104,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,205:7:0 0,18,205:6:0 17 535 . A G,<*> 0 . DP=31;I16=24,6,0,1,1080,39870,8,64,1777,105769,60,3600,611,13341,25,625;QS=2.98623,0.0137694,0;SGB=-0.556633;RPBZ=-0.894788;MQBZ=0.182574;MQSBZ=-1.85164;BQBZ=-1.6854;SCBZ=0;MQ0F=0 PL:DP:DV 0,41,255,51,255,255:18:1 0,21,194,21,194,194:7:0 0,18,189,18,189,189:6:0 17 536 . C <*> 0 . DP=31;I16=24,7,0,0,1095,40551,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 17 537 . C <*> 0 . DP=31;I16=24,7,0,0,1049,38677,0,0,1837,109369,0,0,626,13682,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,172:7:0 0,18,183:6:0 17 538 . A <*> 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 17 539 . T <*> 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 17 540 . C <*> 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 17 541 . A <*> 0 . DP=32;I16=25,7,0,0,1100,40408,0,0,1897,112969,0,0,601,13241,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,180:8:0 0,18,159:6:0 17 542 . C <*> 0 . DP=33;I16=25,8,0,0,1130,41788,0,0,1926,113810,0,0,608,13346,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,27,176:9:0 0,18,174:6:0 17 543 . C <*> 0 . DP=34;I16=25,9,0,0,1211,45383,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 17 544 . A <*> 0 . DP=33;I16=25,8,0,0,1205,45463,0,0,1926,113810,0,0,595,13131,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,198:8:0 0,18,180:6:0 17 545 . A <*> 0 . DP=33;I16=25,8,0,0,1197,44795,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,196:8:0 0,18,184:6:0 17 546 . A <*> 0 . DP=32;I16=24,8,0,0,1136,41758,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 17 547 . A <*> 0 . DP=32;I16=24,8,0,0,1159,43539,0,0,1866,110210,0,0,572,12634,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,180:7:0 0,18,195:6:0 17 548 . A C,<*> 0 . DP=33;I16=23,9,1,0,1153,42673,9,81,1866,110210,60,3600,561,12489,3,9;QS=2.98607,0.0139319,0;SGB=-0.556633;RPBZ=1.57584;MQBZ=0.253876;MQSBZ=-2.34521;BQBZ=-1.68939;SCBZ=3.80814;MQ0F=0 PL:DP:DV 0,44,255,54,255,255:19:1 0,21,181,21,181,181:7:0 0,21,211,21,211,211:7:0 17 549 . T G,<*> 0 . DP=32;I16=23,8,0,1,1135,42143,20,400,1806,106610,60,3600,532,11720,25,625;QS=2.96918,0.0308166,0;SGB=-0.556633;RPBZ=-0.487556;MQBZ=0.258065;MQSBZ=-2.29695;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 17 550 . T <*> 0 . DP=32;I16=23,9,0,0,1056,37314,0,0,1866,110210,0,0,549,12177,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,150:7:0 0,21,220:7:0 17 551 . G <*> 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 17 552 . C <*> 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 17 553 . A <*> 0 . DP=30;I16=21,9,0,0,1006,36136,0,0,1746,103010,0,0,528,11780,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,150:6:0 0,24,203:8:0 17 554 . A <*> 0 . DP=30;I16=21,9,0,0,1008,36694,0,0,1746,103010,0,0,521,11595,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,24,221:8:0 17 555 . A <*> 0 . DP=30;I16=20,10,0,0,1022,36374,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 17 556 . C <*> 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 17 557 . A <*> 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 17 558 . A <*> 0 . DP=27;I16=18,9,0,0,956,35872,0,0,1589,94441,0,0,502,10906,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,153:6:0 0,18,177:6:0 17 559 . C A,<*> 0 . DP=27;I16=18,8,0,1,915,33775,14,196,1560,93600,29,841,473,10141,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPBZ=-1.02726;MQBZ=-5.09902;MQSBZ=-1.41421;BQBZ=-1.54776;SCBZ=5.09902;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 17 560 . C <*> 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 17 561 . A <*> 0 . DP=28;I16=19,9,0,0,973,35555,0,0,1649,98041,0,0,491,10571,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,158:6:0 0,21,194:7:0 17 562 . C <*> 0 . DP=28;I16=19,9,0,0,1014,38392,0,0,1649,98041,0,0,488,10518,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,153:6:0 0,21,187:7:0 17 563 . A <*> 0 . DP=27;I16=18,9,0,0,903,32513,0,0,1589,94441,0,0,485,10445,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,21,179:7:0 17 564 . C <*> 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 17 565 . G <*> 0 . DP=30;I16=18,12,0,0,842,27104,0,0,1769,105241,0,0,479,10389,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,100:6:0 0,21,154:7:0 17 566 . C A,<*> 0 . DP=29;I16=16,12,1,0,920,33998,9,81,1649,98041,60,3600,454,9734,25,625;QS=2.98321,0.016791,0;SGB=-0.556633;RPBZ=0.239193;MQBZ=0.188982;MQSBZ=-1.19024;BQBZ=-1.43942;SCBZ=-0.188982;MQ0F=0 PL:DP:DV 0,38,255,48,255,255:17:1 0,15,155,15,155,155:5:0 0,21,170,21,170,170:7:0 17 567 . C <*> 0 . DP=30;I16=17,13,0,0,956,34312,0,0,1769,105241,0,0,496,10638,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,156:6:0 0,21,194:7:0 17 568 . C <*> 0 . DP=29;I16=16,13,0,0,1060,40304,0,0,1709,101641,0,0,497,10663,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,179:6:0 0,21,193:7:0 17 569 . T <*> 0 . DP=30;I16=16,13,0,0,1061,41321,0,0,1709,101641,0,0,497,10671,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,190:6:0 0,21,213:7:0 17 570 . T <*> 0 . DP=30;I16=16,13,0,0,962,34938,0,0,1709,101641,0,0,497,10711,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,21,195:7:0 17 571 . C <*> 0 . DP=31;I16=17,13,0,0,1069,40739,0,0,1769,105241,0,0,497,10783,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,159:6:0 0,21,193:7:0 17 572 . A <*> 0 . DP=31;I16=18,12,0,0,1092,41268,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,204:7:0 0,18,175:6:0 17 573 . A <*> 0 . DP=31;I16=18,12,0,0,1060,38698,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,201:7:0 0,18,178:6:0 17 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPBZ=-0.173514;MQBZ=-5.38516;MQSBZ=-1.22474;BQBZ=-1.68578;SCBZ=3.60588;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 17 575 . T C,<*> 0 . DP=30;I16=17,11,0,1,1048,41548,9,81,1680,100800,29,841,480,10426,25,625;QS=2.96786,0.0321429,0;SGB=-0.556633;RPBZ=-0.119685;MQBZ=-5.2915;MQSBZ=-1.19024;BQBZ=-1.68121;SCBZ=3.53589;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,13,200,21,203,202:8:1 0,15,163,15,163,163:5:0 17 576 . G <*> 0 . DP=30;I16=17,12,0,0,1043,39581,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 17 577 . G <*> 0 . DP=30;I16=17,12,0,0,997,37255,0,0,1709,101641,0,0,509,11155,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,204:8:0 0,15,146:5:0 17 578 . G <*> 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 17 579 . G <*> 0 . DP=30;I16=16,14,0,0,1038,38820,0,0,1769,105241,0,0,523,11335,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,15,144:5:0 17 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPBZ=1.32953;MQBZ=0.185695;MQSBZ=-1.06904;BQBZ=-1.69093;SCBZ=-0.267102;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 17 581 . A <*> 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 17 582 . C G,<*> 0 . DP=31;I16=15,15,1,0,1080,39870,8,64,1769,105241,60,3600,519,11211,15,225;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.34259;MQBZ=0.182574;MQSBZ=-1.0328;BQBZ=-1.68266;SCBZ=-0.262467;MQ0F=0 PL:DP:DV 0,41,255,51,255,255:18:1 0,24,207,24,207,207:8:0 0,15,151,15,151,151:5:0 17 583 . T <*> 0 . DP=30;I16=16,14,0,0,1135,43913,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 17 584 . C <*> 0 . DP=31;I16=17,14,0,0,1069,39521,0,0,1798,106082,0,0,544,11644,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,209:8:0 0,15,157:5:0 17 585 . A <*> 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 17 586 . T <*> 0 . DP=31;I16=17,14,0,0,1091,39939,0,0,1798,106082,0,0,553,11845,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,156:5:0 17 587 . C <*> 0 . DP=31;I16=17,14,0,0,1078,39466,0,0,1798,106082,0,0,557,11975,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,204:8:0 0,15,155:5:0 17 588 . A <*> 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 17 589 . A <*> 0 . DP=31;I16=17,14,0,0,1156,43908,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,235:8:0 0,15,165:5:0 17 590 . C <*> 0 . DP=32;I16=17,15,0,0,1103,41355,0,0,1858,109682,0,0,574,12576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,194:8:0 0,18,175:6:0 17 591 . A <*> 0 . DP=31;I16=16,15,0,0,1164,44088,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 17 592 . A <*> 0 . DP=31;I16=16,15,0,0,1121,42193,0,0,1798,106082,0,0,583,12795,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,215:7:0 0,18,182:6:0 17 593 . C A,<*> 0 . DP=31;I16=16,14,0,1,1071,39925,7,49,1769,105241,29,841,561,12253,25,625;QS=2.97021,0.0297872,0;SGB=-0.556633;RPBZ=0.559355;MQBZ=-3.80789;MQSBZ=-0.0464238;BQBZ=-1.57464;SCBZ=3.67454;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,12,184,18,187,185:7:1 0,18,174,18,174,174:6:0 17 594 . A G,<*> 0 . DP=33;I16=16,16,1,0,1161,42757,4,16,1858,109682,60,3600,572,12672,15,225;QS=2.99359,0.00641026,0;SGB=-0.556633;RPBZ=-0.998367;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68954;SCBZ=-0.253876;MQ0F=0 PL:DP:DV 0,42,255,51,255,255:18:1 0,21,205,21,205,205:7:0 0,24,213,24,213,213:8:0 17 595 . A <*> 0 . DP=33;I16=17,16,0,0,1136,40412,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,218:8:0 17 596 . A G,<*> 0 . DP=33;I16=16,16,1,0,1061,37187,8,64,1858,109682,60,3600,590,12952,1,1;QS=2.98564,0.0143627,0;SGB=-0.556633;RPBZ=1.68146;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68357;SCBZ=-0.253876;MQ0F=0 PL:DP:DV 0,41,255,51,255,255:18:1 0,21,169,21,169,169:7:0 0,24,231,24,231,231:8:0 17 597 . C <*> 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 17 598 . T <*> 0 . DP=33;I16=16,17,0,0,1219,47333,0,0,1918,113282,0,0,597,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,27,242:9:0 17 599 . T <*> 0 . DP=33;I16=16,17,0,0,1182,43598,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 17 600 . G <*> 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 bcftools-1.21/test/mpileup/mpileup.2.sam000066400000000000000000003145621467060157400202440ustar00rootroot00000000000000@HD VN:1.0 SO:coordinate @SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human @RG ID:ERR229776 LB:HG00101_I_bc_pelib_1018 SM:HG00101 PI:510 CN:MPIMG PL:ILLUMINA DS:SRP001294 @PG ID:bwa_index PN:bwa VN:0.5.9-r16 CL:bwa index -a bwtsw $reference_fasta @PG ID:bwa_aln_fastq PN:bwa PP:bwa_index VN:0.5.9-r16 CL:bwa aln -q 15 -f $sai_file $reference_fasta $fastq_file @PG ID:bwa_sam PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1530 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:sam_to_fixed_bam PN:samtools PP:bwa_sam VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:gatk_target_interval_creator PN:GenomeAnalysisTK PP:sam_to_fixed_bam VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:bam_realignment_around_known_indels PN:GenomeAnalysisTK PP:gatk_target_interval_creator VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_count_covariates PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_recalibrate_quality_scores PN:GenomeAnalysisTK PP:bam_count_covariates VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_calculate_bq PN:samtools PP:bam_recalibrate_quality_scores VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_merge PN:picard PP:bam_calculate_bq VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates PN:picard PP:bam_merge VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.1 PN:picard PP:bam_mark_duplicates VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT ERR229776.1434662 163 17 1 29 63S38M = 189 288 TCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGA ?FIFEDHEHF@EJEHCFEGIFHHHJIIKIIKFKMHLILKJJJFGCF@DHILJMHMDEKDGBIJJJGGK@HMKKFJHJIHCIHLHJIIIIKEIJFEGGGDDF MD:Z:38 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@iiffj_gljjeigihgbhgkgihhhhjdhiedfffcce ERR229776.44080430 163 17 1 29 33S68M = 200 299 AGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCT CEHIFEEEIFFKIHIHEBFHGIKGLJLMKKKKJMLBJKCJLJJGIIJFJKJILJMKKJIKKJLKGFJJKBKJKEDAIKHIFHKLHHLHGLFJJH?CCDFDH MD:Z:68 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@lkaijbikiifhhieijihkiljjihjjikjfeiijajijdc`hjghegjkggkgfkeiig^bbcecg ERR229776.67863896 163 17 1 29 70S31M = 243 336 TCCTTTCTCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAAT ?EEIBDFJFJFGHHHHCA7JII@HIIGHFIIJFILIGDAJLICBIGIGMKLFAFJJILIMILIKF@JGGGJJHILEJMICEGFJIHDIHL?G0=>AH@D@GGG@LDAGFDC@GFF?C6BADEA## X0:i:1 X1:i:0 XC:i:100 MD:Z:63T36 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@ ERR229776.5202330 113 17 20 37 101M * 0 0 TGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGA FFFHGKHJIHHHJIIKLKIHGHGIHBCCHEHDDFFFDFIAHI@CE@EHIHBJIKJKLGJKJFIHJFAJGH=:A6JIHFEDGGHGIGH=HFABDA@EIDEEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.96861155 99 17 29 60 38M63S = 245 315 AATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCGGGGAACTTAACAA =BE:CD5=@;3BC5</>E&%()4'5+')=1,)4?C3B5D?:JH'.5>BH5A;*0$;666@FCHCIEIHHIICGDC:GDGFD? MD:Z:8T0G13G0T1T39C34 RG:Z:ERR229776 AM:i:29 NM:i:6 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.18900347 177 17 69 37 101M * 0 0 GGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGC DCCBFBGCGFFFHKDJDBGGIC?IIBHHGDLIFJKLJKDGIJJJJLJMMLLNLKLFJIHKBFJJKJJJKLILLBLJIHIKKIKIIJJJIHIHHKEGFGIFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:EBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229776.10174020 147 17 73 60 101M = 32 -141 TCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACC CEGFHGHHGJIKDBGGIJAIGDHIFGJFIKJJJKFKKMMLKMLMLMMNMMMJKJKKJHKJLKJKKLKMLBKJIIEKLIKJIKKJKIKJIKDGHHKGDFHBC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.54549035 163 17 122 60 101M = 343 321 CTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAA CIFFIEGJJFFHIKIHKJIKJBJLIIJLMKLJJLLLMJMLNMJJLMMJLKKMFGIJDED=?DA?=FIGGBBCE>C;?EJFGFHFCFCHCHDAHEBCHJHGDJDEADFDFI@GJJE>J@A>D=E>D>:7;@:DDCFA= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.67863896 83 17 243 29 5S60M1I35M = 1 -336 CACGCCCATGTCCAGCTTATTCTGCCCAGGTCCTCCCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAAC ######HIJEG0>><CBCJ9BD:1;.;2>AG;7?8&/7.C8D;>9,>;B87E>A:3:BHBE@A:EA X0:i:1 X1:i:0 XC:i:96 MD:Z:24T5T64 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.96861155 147 17 245 60 58M1I42M = 29 -315 ATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGC CD6;=?GB=-EEDH>IG<=?L@DHBBDCDHHMFCDLGEGG?CJFHGF:EAB0CFHLC>MKGFJI?D@FIILH>IIIIHG;F7A69B=;CA7GEFH/=CB?0 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.70166645 16 17 256 37 47M1I53M * 0 0 ATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAAATCCTTGCTGGTTTGAGAG AIIAMHABJNHLI>COB?CJPHJGPJIHOKC;EJGQGKKI>CFBLGOLDAK6=2G@HLKHH(NHKGPHKN?K>LPB88?A8'&5=FJIJEKCCIM;3MEM< X0:i:1 X1:i:0 MD:Z:81C18 RG:Z:ERR229776 NM:i:2 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.109178428 147 17 278 29 25M1I75M = 49 -328 AAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGT ACICF>FF=CFFFEDFG-6CFDMHHLFACFJ5LKJK@MIIKLKJJJCGHKAJLLIJJHJFHGIKLHEJI@HGKFHLJLHHIKJGIHHCIHAGH:DB<=CC: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229776 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@AD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.33489754 163 17 286 60 17M1I83M = 565 379 CATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTAC CGFFDGHFIFFGHHHKHGKJKLJKBKJJMLLLMKLMJLKMKKLIJLKJMNNNKNMMMLLMNLMJKKIKLGGHHIHJHHHGIJHIKINIJIIIIFHHKCCE= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.67002924 99 17 287 60 101M = 567 362 ATGGTTGACAGACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTT 7<937;A%6@AB5AGBCBG4GEE=;?BDHG;9@D@=;BB@GJ@KKKJDB;:@>C?9C??AEAICI6/9@CEDEMFIEDH?C?GC?DD:DB X0:i:1 X1:i:0 MD:Z:10C90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FG ERR229776.39811680 163 17 292 60 11M1I89M = 579 387 TGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCA ?CGCFE@E;GHC@EFKB=76DDJDI@BGKCLK8JD6JJAIJBGEBBF?>CCAGCDGEIIFCJGGC;FCEDD@HADHE::=IEGJIGIKIJKDHFKIILIIJJJLLLM?KJKMJJGMJLGCIHLFLHJLKJLMNFIKJIJJJNJKJGCAFFJMHFIGLHIHIJKFFDCC=9DHEBD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.47122623 83 17 316 60 4S97M = 19 -393 AAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCATAAAATGATAGCTCATAGTTGCTTTCCTTTGCATATTTTAAAATTGTGACTTTC #####GA7>;IDG@D5LNHDB>8.0DF.FFC::HAA?DD3-BMA;;6+=D=HDD<75'8=<@F@F@<5(G5(%>D>;3*6<'62+7 X0:i:1 X1:i:0 XC:i:97 MD:Z:43G9T14A28 RG:Z:ERR229776 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.54549035 83 17 343 60 101M = 122 -321 GCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAA CFGFDJKJJOHLIJJHGHHIIILJJJLMLKKJMJMJLMMMIJLLMJKIJJFMLLIJJIHJIIIJHKLKJIGEJJGHGIGGGFCGGGFHEIEBDHBFEIFEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.24914793 99 17 348 60 101M = 613 365 TTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACT A@EEFE>ED?;EHGIEGDD@FGEEGEGGDEFIJKFIFFKJIHGEIGIKJIELMMJKEBJFHIGEIJJJLKIJDILKJNDKIKKEJKKEIKKGJHJLGCEEI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.100438586 99 17 384 60 101M = 443 159 ACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGA AACAECGDFCHHIKKFCGHGHLGEIJ=GGJDHJDKMFFHELJHHLBEKKHKIHEHEIJLJNNIGAIIEGEHHGBDCC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.100438586 147 17 443 60 101M = 384 -159 AGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACC HDBEFGHFHFHIJFCELJLKLFFKIGLEJKAIFEJJMJFMJHJKBJKGBJJMJJFIJFGHGAFEHJHBICCAIEFEGDCF@D@@KHEDFG7CHDBC@;230 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.105883979 163 17 445 60 101M = 610 265 CACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAA CGEJFGIJJJDHIHHJHFKKIILLLLIJILLKJKJMLKJJKKKLNMKLLMMLKKKKKLKLLKKKKKNNNMJJOKIAKKKFIKLIKMFFIMKGHIHGHDEFD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HI ERR229776.41759951 163 17 452 60 101M = 681 323 AAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGC :DEEEG=*BCB.F6FGI==IIF1BDIAIJI,FEH=BFFHD,AECEBFFEF=8DFIGJGF4<++*@KEHDGIJKHHG-?C=DHLIF8GFEIDFGE?BBDBAD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@IG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.103175593 163 17 462 60 101M = 681 314 GGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCAC .6:AFFEEB?<8;:IG?DHH?FI9EIIJJHFGK+:BF8DFAF@DGDJEHHCFECHDC6BE@BEEIBGJMJHKOHDEIEFC=BED6:FEEF=G-9AFE=@BA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.28425582 99 17 465 60 101M = 698 315 CAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACG ADD=7HEG2;>@CD7C=@C=@E?CF@?4>BJ>;;9FGH=FGDJHJJJBDC;8=DCEGJGGEHIKHHJEE5@B06C?DHBEHED@# X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.445065 163 17 478 60 101M = 793 406 TAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGG ?FEDFGHFHHDKKEHEJGJ3HHIIIIKKHIJIJLLLLJILAFJJFJKJ?FGIMKIILJHHFEEFH7IFELLDHKFILFGGKGHJGGGAJIIMHEHIEI7;5 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.76793083 163 17 490 60 101M = 728 338 ATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAAC ?EDHDGHDFHDHHEHGHCHHIKLKJFHJHJKIIIJHIJFHKJJJLJJBFDJKHIJMBIF>AGHGMHIJMIJJJKC=IGDCDGJFHMIE@CKDCMHHFFGB# X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.7941745 163 17 541 60 101M = 806 357 ACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAG ?>?FIJJJHH?GDGCEHIHEG7H<:IKKLJKJLADHCFIGKGMIICBILHJLBHIAGL6C8BA2*;BAAAFE>CH=.C;5AE,5)/<4C=3'=8;;*);10*HHH>?CEC(B9)@@(<:(=>;.G762*6JIB>,6(56--/'GF:7D=486A=BA XC:i:88 MD:Z:17C14C0T17C22A13 RG:Z:ERR229776 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.33489754 83 17 565 60 101M = 286 -379 GCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAAC :?DFIJHHICIHFELHIHJHJIHEHGKIKKB=JMJDJFG.>665CE@HFI>G474>9DF>@?FEA=>=JB:GEE@B>: X0:i:1 X1:i:0 XC:i:83 MD:Z:83 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.89263281 163 17 572 60 101M = 706 234 AACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGA CHEJFEEEFIDKIHHKIKIILIILLJLKKJIIIIJJJMMKHJKJNJJLLNMLKMKKMLKKMKNIJMNMMKEKIHIGHGMFHMIGJIGJHHIJIGLGHDGEF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.40976938 163 17 574 60 101M = 796 322 CTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATG ?HDDDEIJFJFHGDHKIHKIIKKGLJIEHIGIIIIIKJHIJJHIJJKLILJMKKMLJKLKNJKMMMNJHLEGHGGGMIHKIGHIGJIHJJHGLHIFHFGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.39811680 83 17 579 60 101M = 292 -387 GAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCT DAFCCC7EA@GFGFHC:0KCFBBD8MLJEA;?><=:HB?3JIKBBAFBHD?FCE2CG:HEGJE<<@ACDFA8BGFDEB<(GEHGFCA?E@:@9E=F@D?8A X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.96748390 1107 17 579 60 101M = 292 -387 GAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCT FDGFIEFE@@G>B0CC@0>@FCE=F@MIEGJIDIDE@EGFG?K=BIIJGFBJHE@=9C@HFJE@G:@@?E=D<5>8BH==@@<;@= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.65100219 99 17 604 60 35M66S = 847 335 TTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGCACATGCAACTGGCAGATGAATCTCAAACGCATTCCTCCGTGTGACAGA 15))2*4?0<4CC>A9<#################################################################################### X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.105883979 83 17 610 60 101M = 445 -265 CACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGG CGFGGEJIHIFMIIGIJHHKLHHEHGJJJIKHHHFIIEBHKLLILIHJJIFLIJILIKHJLKIIJJIHHJHEFB?HIHIIIHGI?EFFGGBBGECIEC:EC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.24914793 147 17 613 60 101M = 348 -365 ACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACT @D>GHGHFLFCEHJIHILHDFGDIIEDLGIHEHGC@BGDKJHGJGJJJGJIJKIKJLMICIJJIKEJHJIF>GGILGKJJH=HGHGJDIKFHJFE>DEHE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.50340221 99 17 667 60 95M6S = 960 393 GACAGAGGAATCTCAAACGCATTCCTCCGTTTAAAAGAAGCCGGACTCATAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACA =FCDEG*.@56BFHG<58&3)1AJ6(>6'=13=.A3:)2DC@:DA(@;D)B@>B89>BG?;8)@EG@3%;A+>GGKHABEBB####### X0:i:1 X1:i:0 XC:i:95 MD:Z:6T23G1G16C45 RG:Z:ERR229776 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.103175593 83 17 681 60 5S96M = 462 -314 ATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGA ######@E;EBD8+8)1$4:>FAJJKMG?H:*6@<>;:=A@D>9G;0@;06JIG@CA/9F>E??C>F>@AD>DF>A@32>@;')8=;.7F70HHIHIC@EA34IHHE@::*-(<:3H7@CF57>F;B3:07C68;,6A8(<;3563C>;E>= X0:i:1 X1:i:0 XC:i:95 MD:Z:95 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.7320258 99 17 683 60 101M = 985 402 ACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAGCACCATTGAGACAGAAAA B+)=AC/=8@4D<6>948=57D;CA@96A;DIB>AG:8>C;;@@EGIA6?FH>EI8CCGJFD=;>20>)1?@8FHC69BI>ABF=C: X0:i:1 X1:i:0 MD:Z:82A18 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@B@ ERR229776.28425582 147 17 698 60 18S83M = 465 -315 CAAACGCATTCCGCCGTGTGAAAGAAGCCGGACTCACAGGGCAACCCACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGA ###################HD@HDELF6=HHGGIE7DEIGFDBG9%B6FF>:BDF@FF@FJHFEHEEEHHKCG?CHF81I;GC2B>ECCCAEGFKGFED9: X0:i:1 X1:i:0 XC:i:83 MD:Z:27A55 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.89263281 83 17 706 60 101M = 572 -234 GCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCC >D>FHGHJHGFMHHIIFGIHHEHIKLJJJJKJHLLLKJJJLLKJLGLJJIEIEB@KKFHFCCKJILIDFH>AKIIIGFGJIFFII?GHEIBE>3IJEE;CFHGBJ=8<8IILFEEIIHJGGHDHIF@7CLGH?0094=094%492;>B=CB'%6BBIED@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.76793083 83 17 728 60 101M = 490 -338 CTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATAT D=JCDB>CB>EFGBA?E>DGEB?CDBFGCI@BEHCAJGCCK=C@F??EA16>>DCMII@LE@CGDI;@DIIHCGG?@=1= X0:i:1 X1:i:0 MD:Z:75T5G19 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.98656758 163 17 764 60 101M = 1003 339 AACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGATTCTGGTGGTGGAAACAAGACTGT CHEFDFGHHHHIHEHKJKLLIILKIIKJEGIJJKLLMLLLLMLJMLLLMKNLLMMLLLMFKJKJKJJNJOJJHJJCLIFHMIGHIGJIGHHJGGCGHDJEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.20493064 99 17 765 60 101M = 1017 352 ACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTC CDGCDEBFDCCHEFIGIJIFGIHCGFHCEDBIIJIKHHKKKKIKKKJLJLEJKKIILK?HIGIELHLILHIGGJHIIEJLHFHHGDDGJHHGIHGJEKFGE X0:i:1 X1:i:0 MD:Z:63T5G31 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.445065 83 17 793 60 9S92M = 478 -406 CAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGTTTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGC ##########CFJE@CGDD@EA;G>>GE8?9?/;AFCHFJJJGBFIDHHIF411A=9>$FC@?FAHDFEC<:8A=GG@;DI=8>E;5:GC4BG:BCE;@A-:>EHJFFHICDGHIG?GEKIHLIIKCHEFB>>=IAIBHHCEE<9BGDA@GBJH8=JD@CGDIJG?FFE X0:i:1 X1:i:0 MD:Z:10T5G84 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.59614566 163 17 820 60 101M = 1133 408 GGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCT :;@=AHGFFKFKIHHIFCHHKBHHLIEIIIAFEKLLJJLKLKDHJJHIIKMMLFJJ7=GGIGJLJBLJLEIIGIEHMILFGHJD?JDDEFFIJHGHBFDEF X0:i:1 X1:i:0 MD:Z:8T5G86 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.65100219 147 17 847 60 8S93M = 604 -335 GATTCTGTTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCC #########FDGFF:DCFDLEA=0D;BBHLF;6GA-6IJJIH=KI9>G@2019BCAB,F>F=AJBFHA?6?DJJDIEH;HCH>BCA;ACA3;;?G>;C8=. X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.70908663 16 17 916 37 1S100M * 0 0 TCAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTCGGAAGATGCCTGAGCCCAGGCGTTCAAGGCTGCAATGAGCTATGA ##J@<:7FM?IMHGLGINGEEJH=>I:MPGD9:NNM?MIQNNMPRJNEMQKLA9D"MLMMM6L2,&PMQJ8?B2I@+:KMN>=2E?AI@HDIFNG8< X0:i:1 X1:i:0 XC:i:100 MD:Z:0T53G9T10A24 RG:Z:ERR229776 NM:i:4 XT:A:U BQ:Z:@@E@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.33718464 147 17 927 60 101M = 717 -310 GGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGGAAGATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGC ;@FCAHGCHGGEHJHIJCJEF?LJIHDED@7CKD;HGJFEIIJGDGBAE5A?IMJLMJGIFLGBIBBJF>LEIJIIF@EIJKICFBHFGKBG?FEFAEGB7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.53110448 99 17 947 29 2S31M68S = 1224 373 TACCATCTATTCACAGTGCTGAAATGGGAAGATTCTTGAGCCCAGGAGTTCAATGCTGTAATTACATATGTTATCGACACTGCATTTTGGCCTGGATGAGA B7:11()8::@A?IJIHJJLKIGJEJFHIIGGEFKHHGGFCB0>EEFDG? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.7320258 147 17 985 60 101M = 683 -402 CCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAA ?CEIDBKGJJIFLFIIJIIFHCGLCCFFJGDDHJBK?GKGIH=GBCFACECHJHJJIFFJKGJJIJIIFIIJIHGJJJHJIIGBHKHFAGFHHHHKFGCC? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IHIG ERR229776.98656758 83 17 1003 60 101M = 764 -339 CAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATG EGGHGLIGIIJIIHJIAIEHHHIIHIHMLJFJIIIHMIJJJHLILIGJJIDLKLIHJCHI>JJJJJJIGIFEJJIIIJIHHFCFGBFAHFABDEBEEEEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.50998015 0 17 1012 37 100M1S * 0 0 ATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTT 327C$2FG8CGM@H?563@3I@%2==H;?*@H;E?BF;M>N7FFHGA8GEGHHJIIJIIHJIIFHLCLKIIKKOJNKIKKKJMJMKJLKLKKLLLLLKMJLLLMILKLMKJKJJJJKIJGIKLIIIIKIIIKHHIFKFEJGFJEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.2114306 163 17 1033 60 101M = 1337 404 GGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATG :;D=IFE9@FED@DHIJGKJKEGELGF>JELIHKKHLLEKLMMKKJLMKGLDLMEGJFHHJFDEKGF@6HJHEKGIHJHDFHFHGCCGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.69497113 83 17 1057 60 45S56M = 717 -395 ATGATTGCGGAACTGGTTTTTGGAGTTTACAACAGAGCAAAAATGTGTCCATAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTT ##############################################@J:+B@;91-=/4*GHF9:H<:04+'751:<48A6:0FC4D;A?;<8==CGD>BB X0:i:1 X1:i:0 XC:i:56 MD:Z:4T0C50 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.83355002 99 17 1066 60 101M = 1294 328 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTT ABD>CCDHGDHJIJJB?>DCDHIHDID,;5(A:@23?838D87<,<7;-EJH@JHCCC>ED<:BKGFBEB98;F?D8AE11665G6DF:+ X0:i:1 X1:i:0 XC:i:82 MD:Z:82 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.69297552 163 17 1080 60 101M = 1344 364 AGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATC ?CHADJJDJHFGKEHIHDAGHLCIIIIIJJIEHIKJILJLLJJKJJLMJLMMJJLMKJJKILJKGDKHKJLKGLJKKIKIKHHKKLFIJIFIFJEGECFEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.44123845 163 17 1082 60 101M = 1361 379 AAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTT CHHIIEKGGFIHHJHIHFJLIJKIIJJJIJJIJJIKILKJJKJKLMJLMMJJMNIHJLILKKCGIKJKKJLLKJKIKKMFLLLBILJJKKKKKHFGHFGCD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EIGGD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EI ERR229776.59579091 99 17 1088 60 101M = 1308 320 TCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGT CBGCIE@GEBBGHIGFIGCFGIHFGCGHGFEKIFIJIHJLHIKIIHJLJKFLHLJLKIKJKKKKLKIIKKJILJKKKKKJKKKJFKKHKIHIHMEEGGGFF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.33511586 163 17 1116 60 101M = 1421 405 GATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTC CGFFEGHHGHFKHJKKIFKLJJKKIJILKIKJJIJIKLJKLLKLLKKLKKLMKKKKLLLLJJLKMNLLLLKMKKKKKLJIJEJIKLLLHLJKIJHJGDAIC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.65575982 147 17 1120 60 101M = 818 -402 CATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAA ACGFDCGIIFDGJJJNLHIH@=NKKKJLNJKKKKMLMIEFKLIGINLJJJHLMHJKJKJEFLLJJHMJIIJILKGIIILHLJGIFFCDEEGGCFHIFGFC? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IKIG ERR229776.45364215 163 17 1122 60 101M = 1385 363 TTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAAT CEFFFKHIJIFHIKIHHJHKIJJIIIJIIIKLJJKJILKHKLKLLJJJJJLLLLJJMJMLKKHLJKKJJKKKKKKJKILIKLHLKLLKINKHGKHHFEEDE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.59614566 83 17 1133 60 5S96M = 820 -408 GAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCTCTAACTCAAAAATTCAAAA ######GJJ@=GEHICDIFNGCFDA@MMLE=AJLEEIIGA5@D>GLICGBAC>EJCD3IA@6F9KH:;BHF=JH@H=@?B=69FF@>GGG7BEEEGCEGGGFACEF:CCB@DCHHEGJHEJCLFCBJEGIJJH;CGCIJIBELGJJC8F X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DDC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.10204227 99 17 1173 60 101M = 1423 350 TTGTAATCTGTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCA :5=DC<<=G++:?>GAF=88=BDFFA9-.8:D9@FJHJEJAB?=D@BCKKFJKJLMCCB:FH68B8@3<;FJHH@D?B?@CBDJFJJC,6,?9BJ?:8:ICICIIMK?IDJDDIKIIJ@;@@B?HC### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229776 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@@ ERR229776.53110448 147 17 1224 29 4S97M = 947 -373 AATTAAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGAC #####C@CEE6,JC+6.I7CD5:22;1A&=FBFABADLKKG>DGG?5H:ACCEJJH>:=C8662CC;E?E6);,4-20,)=(B44316)92:4@DAHH8HF;@CA>?>9ADE8/<8BF:F57C3:9><;C?A2= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.69297552 83 17 1344 60 101M = 1080 -364 CTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTA CGFFIJIIFFHFFLEDBCFFDAAC;F9:1EG>CKLIJDLJ@IHIGKIHIKGIFH98I<7.GB6GEBHBHFFF=BAFH8>>B1 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.31884178 163 17 1349 29 101M = 1660 348 TTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGT &BH>7GDDFGHF@=CDKC@DKHGEILJEJHC&88F=GFIHDIIHC?.@DEA6 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@AD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.44123845 83 17 1361 60 101M = 1082 -379 TGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTG FECDEEFDCGGGGIIFIIBF@FB@=BHAJKMDJJLKCLMIMMLKLMJKHJBFIJI=JGHFJGJGIKIJIDCBDHJFHHEJIFFGJEHFGGBBGE?DCFEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.72241554 163 17 1365 60 101M = 1597 332 GGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGT CBBHFHGFEGIHKJJJJ"1BHGJJ@GIJKHJJIAIKJKJLMKJHKJJIIMIIGMIJGILIFKCFDGFHGDDKMHLJCFBAFHIGHIIIILIJIHHLGFIBE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:HGD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.45364215 83 17 1385 60 101M = 1122 -363 ACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTT />=?GHLHICII?EIHMJLEHGHGFDDDGI=EJGG?GIKLJDIIKEIFKKDBKHIJHIHGHH>HIHF?JH@EDGJGGGCEG;DGGEGFFGE@CA:CECDBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.26840652 99 17 1389 60 101M = 1635 346 GGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTG <?ABECCIJJLJ@BCFAHIJILLCGJIDDGDGBEDJ@+>EGFKHN@CMKIJ;1+C?C3@ICF=D@I?GBA<IEGHIHJCDHCDJIB@DFHKJJHKHJLEIIILJFHJJJJMKJJGK@JJFKJJLJFKJJKCHLJKKIHIIKLIJHIEA&GHHFIKEHJF:KDEFG? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.33511586 83 17 1421 60 101M = 1116 -405 GCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGC CCE@GGIHF=D:EHKEJHHKHFHDBHJEGDEFKIFHEDJGH@IEDIIIKIEKIJKFJHCIDILKIJHCFE7IIHHHJJGIH;BFA:E>F(15.)1'0%1?EB1E(/;3?HHJ5)=CE>5=/8:D89;;EDF=%:A6=#################################### X0:i:1 X1:i:0 XC:i:66 MD:Z:60T5 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.10204227 147 17 1423 60 101M = 1173 -350 TCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGT D>AGEGF@8EBKKDH?DLDB=@HKGCHFGJGKIHDGFFEDHHFHC7KKJKDHMFIHGCJELLFKHIJI>IHCIILC>LGIKHGEHEJGIKEGFIEGFE:C? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.66536220 99 17 1466 60 101M = 1680 314 GAACTGTCCTGGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGAT A@DBIE==>>/<>>HHEDD@GGCDHH8BG>?JE:DIJHGDBD=AIJLJHH0G(>;D;=DHF:G?BEHFEEDHICFGD=6A;>EB=?KJD7>E13?EA2=CD X0:i:1 X1:i:0 MD:Z:10T90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.46562341 99 17 1476 60 101M = 1781 398 TGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCC AABECG5A8>E@C;FD>3F=;=CCEDGCHFC7C6D?@?F@B>CK=EC?ACB?=;6@93E*A??B690<<935:FB>1--?@KC@HE7= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.93812627 163 17 1518 60 82M19S = 1829 411 CTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCA CHFF=GHHFHIHIGKJKGIIKJKKKKLICKMJCKMLMJJJJKKKJLJLD@C?:<>@=DIH,GCCEEBA+6DGC0BCBADCH#################### X0:i:1 X1:i:0 XC:i:82 MD:Z:82 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.9004658 163 17 1520 60 99M2S = 1782 362 GCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGC 7E:EEGFEHFBCKFHBCFAFHHHGKIFJHJEGLKHIJHEJKHJJGFFFMJMGHJHIILLKFCEKDEGCEBCIHHHIIIHCHILH2@?CFHFFIDHBJF### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.78137857 147 17 1530 60 101M = 1262 -368 CCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTT ABFCBF?CIG>:EHJIIFMHICFMDKIFGLJGIIJJLKLKJKKHJLKLJLMJMJLJJLJJKBJHIHLEHIJJJLIHIEKIKKJFHKJIKHEGGEHKFGCH? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR229776.95913538 83 17 1542 60 66S35M = 1208 -368 TTGCTTTTGTGCTACATGTGCAGGGTTGTGTACTCAAGTAGTCGGATTTCCCTCTTTTCCAAAGCTCCTCGAAGGAAAGTTGTTTTGGGATCTCTGCTCCC #######################################################################>D:3EHI?IE5(9=?>*B7/&<-1%')&(+ X0:i:1 X1:i:0 XC:i:35 MD:Z:3G27A3 RG:Z:ERR229776 AM:i:25 NM:i:2 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.72241554 83 17 1597 60 101M = 1365 -332 CCATCTGGTGCCCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTG AFD@BGEBA;"GGBFAB:E>CG@=@@DEKA5AGF?>;:GACD@BADBEGG:CGAEED>G?IDHKJJJFFJIGIKHJII?HGFIH?BIDGCB>FEBCGEEFA X0:i:1 X1:i:0 MD:Z:10A90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CH@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.50673799 83 17 1617 29 13S87M1S = 1336 -367 GTGACCACTCCCTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCATAAGCCCTGAACAATTCCGCCAGCGTTGCCATCTGTTCTGATGTTTG ##############IG@:;@@:B>DC7#8E;D5,*=:#57*824:?GE@<;,9GAAC53?@EGGHLHLHFHIHKHIHHGHHFFHGFJFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AA ERR229776.26840652 147 17 1635 60 101M = 1389 -346 GACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCT @==<5E?8GIMJCDHAIIHIE?EJ?MHED?IHFAGDBEAB.5:>9A6>BB@)=?EI################################ X0:i:1 X1:i:0 XC:i:70 MD:Z:70 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.76819541 99 17 1638 60 101M = 1879 341 AGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGAC A@BDIEAE>'?CB@FHJ:JJDD==8EIHJ?KJLFCGGKHCEED:BHIKDHAF>FDAIGGGICHIHIEHLI4AFIFDJAHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR229776.37392358 99 17 1651 60 49M52S = 1874 323 GGCACCTTCAACCATGGACAGTGCCGCCAGCGCTGCCCTCTGTTCTGCTGCTTTCTCTACCAGAAGTGCCCTGCCCTCCTCACCAAACCACTCTGGGGAAA +(23:@9=7:':++?;8E:@E?('1*?EFE=2&225(6;=+5::AAEH##################################################### X0:i:1 X1:i:0 XC:i:49 MD:Z:10G11T9T16 RG:Z:ERR229776 AM:i:25 NM:i:3 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.5880975 147 17 1658 60 37S64M = 1423 -298 CACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCC ######################################CKEAGEDB@?CKCKLF+35/*:4+&+&/1410')677 XC:i:38 MD:Z:8A5C18T4 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.25705936 99 17 1670 60 101M = 1870 298 AGTTCCGCCAGCGTTGCCCTCTTTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTG 9FD8A?B>;GHIFJC<7@CEJHEBE=HKI@?AHD;A#@/<>C*5DFGFIJCDAK?A>G@ X0:i:1 X1:i:0 MD:Z:22G78 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.66536220 147 17 1680 60 101M = 1466 -314 GCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCT E=DEHEFGIJIJHIKIJIIJGFHKKGJHIHEGKGJKDGJGGKMJILKKIIHC@JKIIFFF@JKKJLLLKJKIKLKJKJLIHCKFIJJJHHFKGHHGDD@CB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.46562341 147 17 1781 60 7S94M = 1476 -398 ATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGG ########CGDDFFIHD@FC8?DICDBFEHDF4684;EA>;8EHE<<5CCC=;7@:0<>@:D=CA>7:49*:CIHIFCH>?GJ;86/9<;??F=1+A?3(=64;:?::,CABHJIHIFIGLFEHGKBECBGA@FAB>>C<;ADCDECA>:AEIEH>BHHIHFIJH@HHEEFFEFDHGJFGCGECGEGG@BCE<@C?F@C X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.59635540 99 17 1831 60 101M = 2100 369 TCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGC =BH99E@;GBAECD9;GFFJJDAFGF=;?DHKFH:4CEJ>C9B@@B?GBD?1083@;AKHLGIGHGFLHMIIAE:?HHIHKDGJF> X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.80549332 99 17 1853 60 69M32S = 2041 288 GACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTCCCTTCTGCTTGCCTGTGGCTTTGAGAAGAA 9>;>5D<6:5;?EAD@@98.8??<+:4@HG:)./=:GE.)337?BJ:GB=;=E################################# X0:i:1 X1:i:0 XC:i:69 MD:Z:16A52 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.25705936 147 17 1870 60 2S99M = 1670 -298 CTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTAT ###8DBED@G@G69@8GCMCIFGFKG;>E9=BH>B@0FCEHKIJHEF7@JJHIFIJJLIDGC5D=AAEHCI??EIHD?BGEF:G@CH=AFKEC;E4 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.11564716 99 17 1934 60 101M = 2208 374 GCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCAT +9DH=77>D@7G;?E=F:@CJG=BFIFFH:7HDCF?A@CHEIBDH?IHILFHKKDIE;9;9AEECHFC82:AHJIIGHIF@GFCIL>IFJIGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.65159506 163 17 1948 60 101M = 2208 360 GAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGA 4DEEEFCDEEAKDFJCDCDGHHGHHHBJDGFFIKJJIBJLCIJHKGCICIJIKCCDFBJKIJKKJHBIJHIMHIHKGIHDGLEIHJIHFFGJGGGAEEE@F X0:i:1 X1:i:0 MD:Z:93G7 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR229776.44568317 99 17 2014 60 101M = 2277 363 GTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGC ADBEEIBEC@@EGAFEFIH@GEEHGGG?GDBHGBJKJGFGHFIFFKGJLFEKJGCFABGG?BGABEDEGFDKGIGH@H@FDGFIG97AE@FBH>@D599*/FHEC@47?560FEGBHEA:AB6-E1+A8?*+:LGHHCC2>+>2>HEACGFH:A/A>: X0:i:1 X1:i:0 MD:Z:0G100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:gPC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.71965236 163 17 2100 60 101M = 2416 416 CAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCT BGEFEGHG=H>HHJIKKHKKKKIIIJIIAIGIIKHMKAJJKKJJJKMMCLKLJKKJGGKGJJHLDIKHEKGHKHEBC8C4DHHHJEDCKHEEDBHDDHCFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.59635540 147 17 2100 60 101M = 1831 -369 CAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCT AF>>BHJ>G:IHLFDEILDDDCFFFFH>FHGHDELL=JKGKKJLCNJ;EILIGLJJHMHF;5JIFJIFE@CFIKHGFILKJF>EEGHG@KI;JHIIGEIFHG>GCBBJEIBJFCGJBGBFLJHMGHNJHAD111AJECDFHMDDHFIHHD;HDCLF9:@CJDCBB6>DCDHD X0:i:1 X1:i:0 MD:Z:0A100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CB ERR229776.8956867 163 17 2145 60 98M3S = 2440 388 AGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCGGCCTGGGGAAACTGGGGCAAGTATC :CE=FGDF9>@BGGD?F@<;GECFLIHKI>FA.>?@>GIIDILLH?EJFFCDKKJIDFGF=CGFFDCC>HEDHLHECBFGBB#### X0:i:1 X1:i:0 XC:i:98 MD:Z:98 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.11564716 147 17 2208 60 101M = 1934 -374 GGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATC BDDHFEGHHJGIMJDCLIKKICHLJKMJLLILNJJJECBJJLMMLJKLMLJLMJKKLLKKKJJKJKIIHLJLLLJJJJGHIHHGJKIHHG?CDHGEFGFG? X0:i:1 X1:i:0 MD:Z:12G88 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GIF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.65159506 83 17 2208 60 101M = 1948 -360 GGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATC B@?IBDAGFFGIMIGIJHHF@JKKDKJGJJFJMGEECBBBFLIFKIIKLKGLJIIIJIIJHIIHCJE>GGBDFDFDBE>GB<1=CEEEDA X0:i:1 X1:i:0 MD:Z:12G88 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GEA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229776.13912851 0 17 2209 37 101M * 0 0 GGTCAACTTCCGGCCTGGGGAAACTGGGGGAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCC G>@GOFHFC>LGG@95'JIG;MCHHI"7::5G:FDH3K8LDFFP?IEPG@IHMPOPJBPRH@B?@=,:DLOFDEJQDDC<>?KL=CB0=INF5AEF>:5@GIKIIJJLIHJOKGFGMMKLLJMHEJ?JLLKJIMMMIJFKAJLMJKKHJEBJJJLHLLIHEF=JEKGEHHFHEFGFFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.68077221 99 17 2314 60 39M62S = 2563 345 TCTTTGGGAGGCCGAGCTAGGAGAATCGTTTGATTCCAGCAGTTTGAGACCAGCCTGCCCGATACGGCAAATCCCAGTCTCTATAAAAAATACAAAAAAAA +-;)5(221::@C/3&8F842:3'0.:",+0D;)8+?B############################################################### X0:i:1 X1:i:0 XC:i:39 MD:Z:0A22G9G5 RG:Z:ERR229776 AM:i:25 NM:i:3 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.60999876 83 17 2359 60 18S83M = 2117 -324 GTTTGAGCCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACTCCT ###################KF=>C=:%+.80/;CB@30C3==;.G::HD<*(G>4-34(;8<6/209>(364-/+);7B X0:i:1 X1:i:0 XC:i:83 MD:Z:79A3 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.71965236 83 17 2416 60 101M = 2100 -416 CTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTG @FJEBBBDE:EGEDEFGI@=0<=DHIHJNHIC=@HID@=HHDJEIIKJEI>JDIGEDB@D@CFHHCIJIKHIJGJJEHJHGGFGGB@EEFECEDDA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.2016000 163 17 2435 60 101M = 2660 325 CACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTTAGCTGTGATCGCATCACTGCATTCCA ?GEFDFKHHGGIIJJHGFKHILLIJKGHEILHKHILLFKMMCKJMJLMJBLBHFIJGHLJEGIBJCDHKGFKHIDIIHL?BCHII=FEFEJGMHHHGGFDF X0:i:1 X1:i:0 MD:Z:74G26 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.101388755 99 17 2440 60 101M = 2722 382 CTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCG :A=DCC7@?;FBBGB::?8*=@5>D7>HBF3B?C?F8@EG?BBCC:??EIE?FH8=:B/<=>HFGGG?CA8G@2AJHKHCF>D@H<=CDC; X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.8956867 83 17 2440 60 7S94M = 2145 -388 TGCCCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTC ########JC@GC<>6&):BC;<;AA=81?E=DEDD@9 X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.13231970 99 17 2448 29 6S29M66S = 2649 301 ATAATGCCAGCTACTCATGGGGCTGAGGGTTAAGGACGGGTTGAGCCCAGGAGTTTGAAGCTGCTGTGAGCTCTGATGGCATCACTGCATTCCAGCCCGGG +2;*;'0.135EB7H?<.2.=&01>3>B<######################################################################## XC:i:35 MD:Z:11G1A9G0G4 RG:Z:ERR229776 AM:i:29 NM:i:4 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.25467915 99 17 2456 60 101M = 2477 121 TCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCA BBFCAGBCDE@HHHFGIIIHIIEIEHJI:@CHIJFKKIGGGIJJJKKLFHDJHHHFGHDGFFHEKJJJJJLLMJILLIKIIJIFDBG/GIIFHJGHHJEFEC X0:i:1 X1:i:0 MD:Z:87A13 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.3800945 83 17 2522 60 9S92M = 2266 -347 TGTGATCGCCTCCCTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCAAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGAC ##########G@=CCE>,EA<<>4:JCGBE<==KJGIGID@G<7?IEB@'C@91F>9EB<(5=G?>JGCB@7AGE;41D;95BF<:DCH6FC:29('/EBFDE=AAEEGGIEGJ';FIIKGHEJHEJKKKHILHIIFFJHLKJJLKGKJILMKALILCJJDLIKHMKKKJKJINJKKKLJKJMGHAIMIHJHIE>FA X0:i:1 X1:i:0 MD:Z:18A82 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GLI@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229776.13231970 147 17 2649 29 101M = 2448 -301 ATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATC 6F=CA96B-EEGF620>,*965AB>=EF?,DCKEEE>?HBE@B@0 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.44981660 163 17 2656 60 101M = 2879 323 GCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCC ?EIFFHHGF?FIIJJIJHLJJKLJIIIICBIIIJHIEHEHJIMLJJMBIIJHFJJKJ>?FGJKKMMNIJHKHBACEGIHFIMFIGIJHILFEHHGDFEFED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ACD ERR229776.2016000 83 17 2660 60 101M = 2435 -325 GATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTAT B?C4=DGB8HJCCIKFGBDHCFGGGHHHGLHDGFCEBBKBIJIHEDLKHKDJLKJHGDEGA;GJKJF@GHBBB>C>EDDGF;CCEBGAIGB@DA:=:CE9A X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229776.74190027 163 17 2668 60 98M3S = 3014 419 CCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTG CEIFEFKHHHIIIHIJHJIIHIJKFHGGHGKKLKLJMMJKLFJLJKLKJJMKMMMLLKMMJFKJIIINGKJJIHJHJMIFKIMHJIJIIMFIIJJEF#### X0:i:1 X1:i:0 XC:i:98 MD:Z:98 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.31785601 117 17 2710 0 35M66S = 2710 0 AGGCAGAGACCTGATCACGGATCACAGCCGCCTCAAACTGTTGGGCTCAACCTGAACGTCCCTTCTTGCCTGGTTAGTTGTTCGGACTACAGGTGTGCGCC ########################################################################################B37.<90;7((/= XC:i:35 RG:Z:ERR229776 ERR229776.31785601 185 17 2710 37 101M = 2710 0 CTAGGATGCAGCTGAGGGGTGCCCCTCTTAGCATCTAATCTGTGCCCTTATTTCCTCTGCGTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTC >AF>>=C6,*58,CCC(%(,9FB?E8$4EIA7/,E@HCC@G?.IGHGC7FB7FF-C=@E;DGGABBEGEEDEG: X0:i:1 X1:i:0 MD:Z:30C29T40 RG:Z:ERR229776 AM:i:0 NM:i:2 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.101388755 147 17 2722 60 101M = 2440 -382 TGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGAC 5BFEDECIICCBFJHKFIEEHEHIIIJHJEIIBA>KHGKHKDFCFBGBALIGIIIILJCIGLIIIF=HIKHKIIIIKJKHHHC8BKJE=JAIF??FDEFG? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.3777343 99 17 2723 60 101M = 2891 268 GAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACC A@BCCA28?A:FJFG>FFH>FIHHKGIKG8@HIGIIFHIJFJKKKCGLJJ8FDFHCEEJFE;>@GHHK@DCCGGIGIIGD?@FFIHHIJHJA:?:>E@C9: X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.16418187 163 17 2727 60 94M7S = 2953 318 GGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTG ?=GEEFFEJFEDGCHG?B8@JHIKG7CFHHGAFIJJKEFJ9=FABI@C1;HIFHEIHIJJ>EILKBE9EA>CLGH7:C(<0EDGJDKFKH:@@######## X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.60225376 163 17 2734 60 88M13S = 3018 318 CTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGCGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGGC 4ED@3FDDF@=JG?HEB=2;ACGD>EFJ>>8@FLA5C>BGF*08=&*4<*7%<))4@?:HAFJ>?HD>EJD:@,<:=CC############## X0:i:1 X1:i:0 XC:i:88 MD:Z:41T46 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.107194084 163 17 2742 60 101M = 3015 367 ATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAG ?EFJFJHGJGFHIJJKIHIJJKHLILIKMJKHJFJGJJKMMLKJAIILMLMJMMIJLLMIGFDFJMKJKKJMKJG>GGC;@GFFB=E@CC@FEHH@2;AD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.107791703 99 17 2817 29 1S34M66S = 3127 380 GGGGTACCCCTGATGAGCCCCGTGAAACAGCCGTCGATTCTCACCCGGGGGGTCGGAAACAGGTGGGGAGGTCTGGGGAGGGGCGTGGCGCAGCTGCGGGG ##################################################################################################### XC:i:35 MD:Z:3G8G8A1C1G8 RG:Z:ERR229776 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.11825404 97 17 2834 37 101M * 0 0 CCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGC AE<EFC?E?>D>GFDFKGIGIHGFIGEGGC5<@FIHFGFCEKG5)+9<:AA=E9;7/"FC?D@7CK8BE@FDFEAH;96D=52;AE7-A8<88CGAB X0:i:1 X1:i:0 XC:i:82 MD:Z:82 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.52739527 147 17 2867 60 101M = 2567 -400 GTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACG BGDEGGC9EMIIJHHFIIFDDFHAHFFIGIGH?GIIIGKJMIJIJJMIIJMHIFHLMJJJLKJFCLKEKJIKJMMILJJLKJKFHAHFIH4HGFHEDFF:? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.44981660 83 17 2879 60 101M = 2656 -323 TGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGG FEGDHIE?F;G9HHEG>HEA8FIFHGICNGFEBJIKJHHH>CBB8:62:A@6?HGCH37(;9@;?ABD>BF<>CC7,2::8>G)17?GBF-:@CH<;CCHAE=:;DBCAEC@(9>B:?D48AKHFGHFDD:CFIHGFICA#### X0:i:1 X1:i:0 XC:i:98 MD:Z:6G90T0 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.3777343 147 17 2891 60 101M = 2723 -268 GGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCA DEAGCHE=>EIHIIKFHDKIIFMHIIIFFFGAECECHFDFAHICGJHLHMKIJJKLHJG:<1<@C6*>EA6*07D;A@D? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR229776.16418187 83 17 2953 60 8S93M = 2727 -318 AAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTAC #########GAG=;7FE7:)C>E?;:EF???JBJCE:GEA=9<77IE@<=F?>@BCJKGGJ>97-<5?A?EA@D;HDI@GI;67A7ECBED= X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.89222254 163 17 2970 60 96M5S = 3189 319 GGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGGGGTACAGTGGACAGGCCCTGCCCAGATGGC 05=DFGE/BD@I+:FG?E6EGIJBFG?DEHFH@AFDBGG:ED;DICIHIGHMF1;@ECBD@+<:+>)@9B&=66<:=BB>>>6>DC*?@EC:BEG###### X0:i:1 X1:i:0 XC:i:96 MD:Z:0T69T25 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CFK@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.25895864 99 17 2976 60 101M = 3273 397 GTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCG CECCCG@DEA:DJ@HEGGBB8B@FEHHJAEGII>EBC@D>AGGFHKIIF<@IJIAEA@=>EGIB@EDBCBFA4<D=)8?ACC. X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.74190027 83 17 3014 60 27S74M = 2668 -419 CTGCGGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGG ############################D?8789?>6?51:D>5.@4:9<:92:5295A3.38;:37:52DE@CECGEC X0:i:1 X1:i:0 XC:i:74 MD:Z:74 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.107194084 83 17 3015 60 6S95M = 2742 -367 CCAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTCCAGTGGACAGCCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCA #######??68;7GC=7+0FDEED77(+DG76<3/%*=4-<<1+21"A8;<&<43-:6,5@AACGD?>A@9BB>B8:AIHJBDFC@BDJE9ADEDEECFAA X0:i:1 X1:i:0 XC:i:95 MD:Z:29A10G54 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.60225376 83 17 3018 60 66S35M = 2734 -318 CGGGGCCTGGCCCTGGGCTGGCAGGTGGCCCCCAGCTGCTGGGGTCCAGCAGCCCCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGAC ########################################################################7E=CA(5.6;4=DE?= X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.4450150 163 17 3027 60 101M = 3312 354 AGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGC ?C@DCGEFFGFIGFHGE@@HIIIIK?FJIFHKMKKIIJHLJLFJJLHII5 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.49925000 147 17 3075 60 101M = 2880 -295 CGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCA DFCCIKEEIHFAJIHJIFHKFKGEDLB>LIJJMACCJJMJIEJGJJIF4FLIJ@HDDLJJKFFNHJKJIGIJCEIJE@@CBCGJHHHGDHCI@> X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.107791703 147 17 3127 29 30S71M = 2817 -380 AGACCATCTGTCACAGCAGGTAAGCCTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTA ###############################IG++HE>E<12.@99BCEF@6EG6BC,E(BF:>:>GELHDAC9@9GEF>G>CAE;& X0:i:1 X1:i:0 XC:i:71 MD:Z:71 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.99540436 147 17 3147 60 101M = 2895 -352 GTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAG CDDFEFHKHIFIHHGIJGJGIGJHIFJILGHKIIKKKMJJKKGKKMKNMJLKKKJIHJIFB:LJJJLKKI>LLKIIJLJIJHKJIHAGEIFFGHHIDDDH? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.89222254 83 17 3189 60 101M = 2970 -319 ACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGA FCEFEJGIFHFHEHHJCGHIDBD@LEB=8@DG>B:>53+14)A:2'DEFGA5-<39?C9DBGK?HEC>ED9#7HA2>C1ED@E6AH<@GD@GCIDBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.27664076 99 17 3197 60 101M = 3465 347 AAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGA ABGGGEB;@78DCAFCGH8@F?=6;%806CHHI?H018D0;AGH@HHH<;GAB/?AF8EA)9@H@A@??HBEEGCFF2>:<:GBBF?IF=BHCEFGCJI?=:GFEAIFGHG8DD@HJKJLFBHHI5AJEJFFEE33?E@DJEFIIFHHFIGGHHEHID5DC<JMMBJLKIEKJLLKJIIFKJKKKJLILKIJIJG=EGJIHJI>DGGGHEFFEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229776.31259015 99 17 3281 60 101M = 3514 333 AGGTCAGTATTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGC 7<8ACD<-.&)9:<<@7;9@HDCI>>/:<@@HFBBIBAI;=7;DAFC8<-@@==+,BFFC7ADBJBGE:I9;)B?CA;;;=3FFHFBD;HLG################## X0:i:1 X1:i:0 XC:i:84 MD:Z:84 RG:Z:ERR229776 AM:i:0 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.32427229 99 17 3347 60 101M = 3572 325 AGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGAT A@FDIE@E<;BFD@?C?IFEHHFIIEGKEFFJHJKKIHLIHKKDLIKLJKGJLIIIJGEJFIIEKGFFJGFKGEEGBFFIHJFAGCDIJIIHJHILGIFGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.26612274 83 17 3349 60 101M = 3093 -356 GCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTGCTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCA #BDDB:FIECE==:A@AJGDA57C;A@='>?CCFEHF?@C@LDF>HHIKHHE4C@DJHH:?FGHAA@?IEDB;D7>@D79G:?BE<9?BICDGAA X0:i:1 X1:i:0 MD:Z:0C33A66 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@F@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.38128366 99 17 3399 60 101M = 3700 401 GATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAA =@ECEC9@>E?IDACD8?>HG;C?@=9FCE5?BDCGA>D?>AI=74CH376*:+0;EHKDB->;E;B6,57,I>=FB)20=2490BFGGBDGD?;C,0@07H@0CF10+9D14:CDEEE9@@GCDBD>>@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.27664076 147 17 3465 60 21S80M = 3197 -347 AGACCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCA ######################CDIGFIBHGBG9C>ECG9:6A;.<4:<=ACIIKKJJHLKKIFEEBAJHHCMKJJKIEJGLHAGHHEHGFIGFHEEFEC? X0:i:1 X1:i:0 XC:i:80 MD:Z:80 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.46260219 147 17 3469 60 101M = 3225 -344 GGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAG B?@ABG;AFE,=D@>;FG7B956B9AABEDDDKKGIKJLGGGKCJJACFGJMKMKJMMKNKJJIJIGEHCLLIKIJLHIIHHGDHHAJ@GDHHHHJFEBHC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.51706669 163 17 3478 60 93M8S = 3757 379 AGTAAGACTCTGCCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGAAA BEFFIGIEJHIH:CKHHKGKLLLLLLMLMFBD48?CCC@CHIDHJCGECEDCFAHFAEH@EHGADHIJGAA-6>A@EH6/;3+;CB=DBGJC######### X0:i:1 X1:i:0 XC:i:93 MD:Z:12T80 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.38173578 147 17 3478 60 26S75M = 3262 -290 CCACTGCACTCCAGCCTGGGCAACAGAGTAAGCCTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATA ###########################E@FEB/<:=C?A:DB<>EEA8B;?;@6>A632:CIICIE##################################################################################### XC:i:35 MD:Z:18C6T6T2 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.31259015 147 17 3514 60 101M = 3281 -333 ATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGT C@AHHEHGJGFLIAKJIHFEC=BDI?HJJGDIA?DFCAKIF=L?EKLJKJLC;JLJLHKJJDJAJBF:JLIIIIIHJCIGHHD=EHHCGE9HFCDGC>I@: X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.89637749 163 17 3537 60 101M = 3762 325 CTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGT ?K+=EFHGJH@JHHHIIGIAKBIIKLMJKLJMLIJJMKJLJKMMKLJCKMJLNNNMMKKKJKJKJKJHBKHFGFEJGHHGIHNIGMIMIJIJIIH@HCCAC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229776.109591233 147 17 3541 60 101M = 3310 -331 TGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTG EFECKIJJKKIIIJ?J?GJIFFIHKIELIKHJGKFKJJJJKJMKJMKKLLKKHJJJJJJIIIJAJIJJJLIMIIIJILIIKIHGIHHFGJ:FJJGEIFEGC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.32427229 147 17 3572 60 101M = 3347 -325 AATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTC DEFECGJFIGIMIFFFFFFKFDIKHHJJGDFE?HBIIFDGLGFJKGKJHKIKJKKJKJJ?HJNKIMJJJIMMMKBLIJLKKIIHHAHFGKFHGHHGGFEG? X0:i:1 X1:i:0 MD:Z:15G85 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.40459217 99 17 3602 60 35M66S = 3843 307 TACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGCTGTGTTTTCGACAGCCGTCCGCGTTATAATAACCCCCCTACCTCAAATTTATTCACTTTCAACTC =4>@G:=EG=FKHFGG@HE6>FGA?GIIHE?HE6FJFI.:HGFJLJAJ+-5D??B9AAFEEFDD9A1@EBDIDDF?C.CDDHIFGHHHF?8DCICEF X0:i:1 X1:i:0 MD:Z:52C48 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.104546030 163 17 3615 60 101M = 3837 322 ATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACAT CEFEJGEKGHFIHGGHH>HIJIIJIFGIIKKHALJJJMMJJKLBJJGJJJJNKJNKLMMNMNJLJKKJMMKKKKKIHKLFKKKIMHMKIJKKHIHFGGDFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.37380040 1187 17 3615 60 101M = 3839 322 ATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACAT ?EFEIGEJGGAGGCGHC:EGIGIJJEHHIJJIAKIJMIKFJJI?FFGBEIJMJJCGJHJMLMFCECJIMMJKKHHFHILIKKKFEHMKIJHFHHHFFGD:B X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.83861944 163 17 3622 60 101M = 3858 336 TGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACAC 4=EAF@DADF9HDG=E?;DEDAACE@EFIHHLJEEH=4A@BACECFELDIDDJIA8CJJKIFDGIGBGHKIFFEJFDDBCHIHFCHHFDEGCHJDHJDJJHNNLBKKKNKMJJLLAJJJMJJJKJJHILKLLKGJLILIGIJILLIHLJGFKKJJHIHJKIGGGEAFBBFAGGECEE=DDEGDA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AEAD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.25245101 99 17 3650 60 101M = 3870 320 AGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCT A@=H=A<@,5:BF=FAIGBC>G?MAB-=GDEDB>A=GIKJKHDEFJJJB4>DACEIC6F?IEH+?@KEAEDDI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.38128366 147 17 3700 60 101M = 3399 -401 CTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTC AHBEKFBFGHFEGCBDFGJJMKJMLFCFKJLLMLIIJKJKJIHJIJJJKJIIHDHJJIHHJJCIIHJGEIGFFEGFEEGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.45938508 99 17 3704 60 97M4S = 4005 401 ATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGA BEECEE@D?@;GGHGBFG@CGD>C>:BEE=8BBC>CEGDFHEGHJJKH@2;?>H>9FFGI.0A?IGJM5B.;IEHGJ=GD:1319:GFBFBHD@FG##### X0:i:1 X1:i:0 XC:i:97 MD:Z:97 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.94413412 147 17 3754 29 1S100M = 3490 -363 CCCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGGCCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCT ##?>@E>6AA@CHDGE;FBH<9<->:>BD>CHDC?EC6G-+@CD8IBB/>DDF?;A:FFDMGHFIDLJKGJCCHAIADF?2+D=??G>6?=44:B>>(:F>=97-$65=.6:<: X0:i:1 X1:i:0 XC:i:46 MD:Z:37A8 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.51706669 83 17 3757 60 101M = 3478 -379 TGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTTCAACACGTGGCCGTCTGTGTCTGGCTTCTC H6<6>CDGHFD>AIGHEH?A;HB;.;A12000BC<=:D1FJEIGFEIIGHKHGHH?91'::G@E?FCFD57GHCGFGEDCDD?.<0(,9+<2+7E@@/CAFHHIFJFE4GIICE<3HFFC-CBA<7GFIEC6GIJEFGGGGAD@+DFEDEFDIHJJAJLKKHJKLKKLMMMKKLMKCLMMJMLKJKJMIILLKKJJKJIJJIJEGGFHKDFEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.21787291 163 17 3825 37 98M3S = 4149 374 CTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATNCACCTGCTACACTCCTTCTTAGGG ?HDEFFDGF>>F6@H?IIIHJJJLMKBCFJ@DFLFCGHJJJJIBC757?FHCDFF#67:FH8CIHHJHIDHLHHJF#### X0:i:1 X1:i:0 XC:i:98 MD:Z:76G21 RG:Z:ERR229776 AM:i:0 NM:i:1 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.104546030 83 17 3837 60 101M = 3615 -322 GCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCAC C?>EIHIGICJIJFHHHJHHHI@JJMJNJKJLJLJJMMLIJIKIIKIHKIAHHKLHHIILJHIGFF@JJHFIHGD;HBHIJGHJGHHHGGBBDEBGFCCDC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.37380040 1107 17 3839 60 2S99M = 3615 -322 GCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCAC ###BIHIGICGDG=)HJHDEHI<@GGEIAGBKHLJGMKKIFKJD@DDEEG>F>EK@ICILJJHHHF;JHHFEEGC8JI=IHGDJGAFEGGB@@EBGFBEDC X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.40459217 147 17 3843 60 34S67M = 3602 -307 GGATAGAAATAGAGGCCTGGAACGCGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCT ###################################CG?+GB*7*C;F;4=HF;?F3@ECBCF(ECKHGG>9HB@<@9>9BEACF-8EE907EED?: X0:i:1 X1:i:0 XC:i:67 MD:Z:67 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.83861944 83 17 3858 60 101M = 3622 -336 TCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTT D;GFIF=CD>D:CJHIJJEHGJD:<9:8?<:9JEHEE?<>A?BD6?C>.EJ??>AGJBGFB8694BAHHF@>?<>=9=D=F@B<3+7G@EGFB:9 X0:i:1 X1:i:0 MD:Z:78A22 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.22665016 83 17 3861 60 3S98M = 3604 -354 TCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTT ####HHI?9>A+CJHJIIA377&041;57:=D;=3++.(:>CB=;+ X0:i:1 X1:i:0 XC:i:98 MD:Z:75A22 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.26430745 99 17 3863 60 101M = 4142 374 TAGCATCTTGCTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGC BEEEEEBIE>-EFFHEJHH@IFGHJHHHBCBFCCIJIIFJHHKIJKKIGI@MKLMKLJKDJBFFLJKJIDJKIJJCKIIGMHKMKGJGMIHHHHKGGDF;> X0:i:1 X1:i:0 MD:Z:10T90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.25245101 147 17 3870 60 101M = 3650 -320 TTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATT CDDHHIDHFB@,;@DICEHHEFEHHJLFE?D??ABCCGCDGCFGEJKMKHKJMIICIIFJJILKC?H?EF=IJIIJGFFAH>CB@IIHHHBGFFGGEEFA? 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A <*> 0 . DP=6;I16=6,0,0,0,232,9002,0,0,360,21600,0,0,113,2597,0,0;QS=1,0;MQ0F=0 PL 0,18,152 17 1051 . A <*> 0 . DP=5;I16=5,0,0,0,191,7317,0,0,300,18000,0,0,115,2675,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 1052 . A <*> 0 . DP=5;I16=5,0,0,0,189,7223,0,0,300,18000,0,0,117,2757,0,0;QS=1,0;MQ0F=0 PL 0,15,135 17 1053 . A <*> 0 . DP=5;I16=5,0,0,0,187,7027,0,0,300,18000,0,0,119,2843,0,0;QS=1,0;MQ0F=0 PL 0,15,133 17 1054 . C <*> 0 . DP=5;I16=5,0,0,0,184,6852,0,0,300,18000,0,0,121,2933,0,0;QS=1,0;MQ0F=0 PL 0,15,132 17 1055 . C <*> 0 . DP=7;I16=7,0,0,0,255,9635,0,0,420,25200,0,0,123,3027,0,0;QS=1,0;MQ0F=0 PL 0,21,161 17 1056 . C <*> 0 . DP=7;I16=7,0,0,0,252,9454,0,0,420,25200,0,0,127,3127,0,0;QS=1,0;MQ0F=0 PL 0,21,159 17 1057 . T <*> 0 . DP=7;I16=7,0,0,0,269,10389,0,0,420,25200,0,0,129,3133,0,0;QS=1,0;MQ0F=0 PL 0,21,164 17 1058 . G <*> 0 . DP=7;I16=7,0,0,0,281,11297,0,0,420,25200,0,0,131,3143,0,0;QS=1,0;MQ0F=0 PL 0,21,170 17 1059 . T <*> 0 . DP=7;I16=7,0,0,0,257,9509,0,0,420,25200,0,0,133,3157,0,0;QS=1,0;MQ0F=0 PL 0,21,157 17 1060 . C <*> 0 . DP=7;I16=7,0,0,0,268,10392,0,0,420,25200,0,0,135,3175,0,0;QS=1,0;MQ0F=0 PL 0,21,164 bcftools-1.21/test/mpileup/mpileup.3.sam000066400000000000000000003164641467060157400202500ustar00rootroot00000000000000@HD VN:1.0 SO:coordinate @SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human @RG ID:ERR229775 LB:HG00102_I_bc_pelib_1019 SM:HG00102 PI:497 CN:MPIMG PL:ILLUMINA DS:SRP001294 @PG ID:bwa_index PN:bwa VN:0.5.9-r16 CL:bwa index -a bwtsw $reference_fasta @PG ID:bwa_aln_fastq PN:bwa PP:bwa_index VN:0.5.9-r16 CL:bwa aln -q 15 -f $sai_file $reference_fasta $fastq_file @PG ID:bwa_sam PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1491 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) @PG ID:sam_to_fixed_bam PN:samtools PP:bwa_sam VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file @PG ID:gatk_target_interval_creator PN:GenomeAnalysisTK PP:sam_to_fixed_bam VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) @PG ID:bam_realignment_around_known_indels PN:GenomeAnalysisTK PP:gatk_target_interval_creator VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing @PG ID:bam_count_covariates PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate @PG ID:bam_recalibrate_quality_scores PN:GenomeAnalysisTK PP:bam_count_covariates VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing @PG ID:bam_calculate_bq PN:samtools PP:bam_recalibrate_quality_scores VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file @PG ID:bam_merge PN:picard PP:bam_calculate_bq VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT @PG ID:bam_mark_duplicates PN:picard PP:bam_merge VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT @PG ID:bam_merge.1 PN:picard PP:bam_mark_duplicates VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT ERR229775.22049853 163 17 1 29 80S21M = 115 213 AGGCTCAGACTCCTTTCTCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGGCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTG BDBDHECFF@D=DA>CIJIF8E>HBEEBH@AA8>GH@BIJI;?CC95@@?*2-67=6?$6ABDGD6GGHKGEGHIJIH=BFIKI:DEADBH>CFIE MD:Z:21 RG:Z:ERR229775 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ihg\aehjhYcd`cag]behd ERR229775.4635304 99 17 1 29 9S92M = 250 348 TTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACG BFFKGHHHIKIIIKIKLKIILHMKJJLLMILJJJMLJJNKLLMKKJLJKNKLKILNKLKMLINLMNLMNKJJKLNKMKFAEHGMKPLHFGJIMIKFFFE@; MD:Z:92 RG:Z:ERR229775 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@jhhhjhjkjhhkgljiikklhkiiilkiimjkkljjikijmjkjhkmjkjlkhmklmklmjiijkmjlje`dgfljokgefihlhjeeed_Z ERR229775.76124411 163 17 1 29 12S89M = 253 351 AACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCC @BDIFEFFEBBGJIHGJHEIJHGJJKIIIIJKHHIIIJKICKHE@>1;<=E?CG?F X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR229775.71066602 99 17 35 60 101M = 291 355 ATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCT BEFHDHJHHHFGLIJIJKKLJKLKKMJIIHJLKMJJLMGGLJMJMMMEJMMKKMMKJ?LKLJMHNJIIMHCFHGMFCIJDHJICAIDJJFIHGGIBBHEEI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229775.57643739 113 17 39 37 101M * 0 0 CAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCC DEEFHE@C?HCHHAIJIIJIHCJEIE;JHFEEFHKFJFJIEGIJGH>9KJD@;EFCJIFA=JFICKIDCFJGFC?IIJHHHKHB@IICIICGCGJGDDH?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.24343576 163 17 62 60 101M = 322 360 GTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAA @DCDHCFB>,,FGDGFHGC@FHFIHGIKH@2JGH@JGJ?EJHCA5?BLIHEJHIGFEB@BG;BBEDGIEDGGGL;FGFI;A37F9F2=@JCDKHJGAIGFEEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.48988007 99 17 115 60 101M = 371 356 CAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAG ?GDCCIGFKGFKGHKKHGIKJIIKGJHIACKFGHCKHJJJFIILGFGMK@CKFIHHJHI>JIFJMEGADJG>FEHJIIIFHJHIMDHKGIH?CJGGFFIE8 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.22049853 83 17 115 29 1S100M = 1 -213 CCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTA ##IDEBEBHKIDCIFDIFGKD?EHA>BA;GJHIABEGEFGIBDGIKGJMGJIJKHGHKJALJJIJ@DCECE>EIIIHHIKDEFHIEHGHHGHGFEECCD@7 X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229775 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.6535575 163 17 136 60 101M = 400 364 GTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCCTGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAG @:9D&@9/0<98DBCCGCDG:?E=>D><+/;7A:=HE71)61>4:KDDIKLJJGJH=6GAIGEIHCHGB@?>HBFHGHBGDFKFGKHGFCFFGBBEJFIJMIFIHJJJLIDFF@HDKHEHGFEHLHHDEFDB X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.74734077 163 17 164 60 101M = 421 357 TGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCGCCGCCCAAAGCCACGCCCATGTCCAGCTTATTCTGCCC 7+>C1A5?-3&B<:EA:(86>A4F8=B<7>7D52@7=>CAE5DK.DCF>(-706B=ACA>D<@IE4:D;CG;@BH9@GH@CCJ@G=B@;ED9E@BHDBFHGI;5ABFHFIG=FCE/=GHHEJGJF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR229775.86942903 99 17 232 60 71M1I29M = 471 339 CAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTT AGHIGIEGD>BGHFHHIKKILKMIIIHIKHJKLCEFJJFMDLJIFHKLLKDJGBEGGJ?@GFIIKIH?GGHDDACIB?>DDJFGII1?,9ED*@>D@FCE= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR229775.4635304 147 17 250 29 53M1I47M = 1 -348 CAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTT EIGGGHHHHCJICGIMGCJGHKCFDJOJJKKIJKKKJIKJJMIIJJJHEHIGILLLLGLBGDJJJLKGIKHGIIKHHJHHKIFHHCG;HFBCGFBEFCDGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG ERR229775.76124411 83 17 253 29 50M1I50M = 1 -351 CTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA DDFFFGHJIGHINGDIGDJIJAINKELOIJLKKKKKMJLKKGJKJKLNKKNMMMKLBLJLLLNMMJKKJKKJJJKKJLLIJJHE@KJJJKFHIHFEIIHFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.72556128 147 17 262 60 41M1I59M = 22 -339 CCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAA DDFJEGJGC@IKEINIFFMHKHIJKKKIIMJKJJJLKKMJJLKKMJLCKKFKKMLLJKJIIKKIIKJHKLGHIGC>HHIJKFHHHGGIJGBEEJAEEIFEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG ERR229775.73749010 147 17 283 60 5S20M1I75M = 28 -349 AAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGT ######G?<7G9;+@-DEI=CHOHKOFBHE9BHKFE>JHDH9?GHFDCBKCIHA;E=C;9>@A7HA?;AGADHBGHGG@@:>8HG?D9DF6/;@=>:BBA;FEFGH:A7E<&>HAJEIEKKKJGMIJGILKMGNLLKLKIEIJHDIEFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229775.65476258 99 17 324 60 101M = 548 324 TATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATA BFFFGHHHHKIJKELKKKJJJLKLIIJIKLLJJLJMLMMNKLLKFJMNMKKJMKKLMNLLKKNLKLMKKKKLLKJNNNLILKLMJNLLKLKIEIKHGHGFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229775.44063798 163 17 331 60 101M = 608 377 TAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGG @92:9C:E>:EFG>H@ X0:i:1 X1:i:0 MD:Z:0A100 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ZS@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.59467859 147 17 359 60 101M = 159 -300 GAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCAT DGCDGIEEDKK>LIKHIGMJFHLNJFHLIJAJIIFMMHDIJHGIHIJLIC?LJIEDCA=<3AJIHID)MJGD=@?<8*4JCCA8@928-=92)2@975E)BFE8-;L>CFC>8K?E=8''?@9A>6C694*%;,/44* X0:i:1 X1:i:0 MD:Z:4A25A63C5T0 RG:Z:ERR229775 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.70199275 99 17 391 29 101M = 711 374 ATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAAT ?EFGGHHFFIEIIEF?C@ABICJICEIJJJLLJJM?H>HHCFI:G>AEHJILLFHGCMJGLKEM>-5A8BKE;JIJHFH4AEIAGMJDF@EHKJHJLHD9JKJN?JLFAG=GMGKKJIAJAJGHI@JGIKKIMHLIIGDILHIF>CGJJLGDC8DHHLGFGFE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.5711913 163 17 409 60 101M = 646 337 TTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACAC <@CDFD@A?HIIGFJKJLLIFIFCGIFEEDF@KMC?EI=<<GGCDEEFDD7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.22701711 163 17 421 29 101M = 699 375 AATAATACTGGTTTATGACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGGAATGAAGACATATGTCCACACAAAAACCTGTTC 93:<>>FC'?IHGIKH7KCHCGJFFJHEFCHJJMCLAHJDHKHMGHMLMEF@IBFIHI@DA:HCIGFA83>=0HHEG7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.52216469 163 17 454 60 101M = 693 339 ATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAA @CEEFFBFE:<>:MEMIMED1N?LLQKQD9)@GNLKB@GHGFA;>A>D>;A;H=?B5DIEAFEC>-(7@C8BAD5>7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.82457097 99 17 474 60 101M = 695 321 GGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAAC A?HGGHHFIGHIJFJLLDEJLJKIJIIIGJLMJHIHKMNNNJMNLJJMKKJJMKMMMLLLNJJMKKLKJMKNNNNIKKIIKMJMHGFKGHC?FEHLDFGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.93698964 99 17 499 60 101M = 735 336 TATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTT BFFGHGFHFHEIKKKLIKLIIJLJJKKLJLIMKKMMJKMKKMKKMKNNMNKLLMKNNKKNKMKJKKBKJIOJKKGINHGEGHHGMIJIIJIGJHFIBFDHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CC ERR229775.17900575 99 17 527 60 101M = 760 333 AGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCAC BEGKGHGLHFDIIGIIKILLLLIKKLJMLIJKILJIKJBMMMNKLKMKNLMMMJLJMMKKKJLIJMHKMIEMJHJICJFDFHIHJGGGKDIIGJGHIDEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.65476258 147 17 548 60 101M = 324 -324 ATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAA BCGGGE@GIAJGDGIHAIGFKNMJKKJKJHKLJGKKJJLKKJJHIKKJJKGJJJKILGGHBHFBHHJIHIGF:KGBJIEJKFFHGAGGHGBBHD;DCEEEA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CA ERR229775.83749675 163 17 553 60 100M1S = 783 330 AAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCT ?<:GH:?I59=G@JHHDC3D'6@?ACFHI:E?>;BG=BECFIBH:6?E<6?GDEDHDCHDE65?=GE## X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@ ERR229775.19017039 99 17 560 60 101M = 839 368 CACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGGTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACAT ?GDB=1GFFK:GHGH=F?G=CHJJ?DJLGGDGCCC6CIEA?.@E9 X0:i:1 X1:i:0 MD:Z:44T56 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.78639790 147 17 590 60 101M = 335 -355 CAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTC CFDGCCHEBGDGFDBKCACBCBC?HKIKDGKLEJJGDHMDG45?IIFIHDEDHIBHA:94'ECEFHC=EH>BFGB@@?:?CEFFFBKJG=JD>EIGFGHHLGBECIKJJ?JLBG=JHGHIIIJMHKKIJGIIC5FGIJGGEIGGFEFIEEHE7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G@ ERR229775.47649789 147 17 647 60 101M = 392 -355 AACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGG 68BIAGJE?C?=8JI=5@EIEJHLJJIHGGGBGC?=.?JBAAG=A4EAHJ=FFJJJKJLHH@KJIDHB=HF>?FF>HF@FH;DGI@GAGF7@;@=;3?DBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.52216469 83 17 693 60 101M = 454 -339 CCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTG C=DHEIHFFLIANGFAKIJLMIILOKJJKLLKKKKNKKMMKLKMKKNNLLKKMMMLLNHKMKMKJJJCKLKJIJILKIMJLLKGJLKFIIGHKFFHFKEHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.82457097 147 17 695 60 101M = 474 -321 GTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGT ?HEFAC>LEAG@C=A@GKKCFHLJJKKJHFCHGKJJJEIGJMJEKFIJJJCHIJKMIFJIFFJJI@FHGH>>;HEEIFCJJ=DJGCGBBEEACFBICEDDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.22701711 83 17 699 29 3S98M = 421 -375 TGTGAAAGAAGCCGGACTCCCAGGGCAACACCCTATCCGACTGTTTCCTGGGAAAGTCTGGCAACGGCCACACCATTGAGACAGACAACAGGTGAGTGGTT ####FCGEAFD7::.:DB;'=CB+D@BFFF;2C<,8-%H@C@FI;F-+KIHDCB@57CID<*A4/)G:)ID0IJGKIDIDGEH8<+==FLAEGCKEFEDD? XC:i:98 MD:Z:16A11A5T9A13A6A16A15 RG:Z:ERR229775 AM:i:29 NM:i:7 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.70199275 147 17 711 29 46S55M = 391 -374 CAGACAAATGAAACTCAAACAAGTTCCCCCGTGTTAAAGAAAACGAACTCACAGGGCAGCACACTATCTGACTGTTTCATGGGAAAGTCTGGAAGCGGAAA ##############################################CC<+2:::)HD@(8<6C?A;?>=>,'7(>@3>6><=<1;+7:8>A4@9%.*<07* XC:i:56 MD:Z:12A35A3C2 RG:Z:ERR229775 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.93698964 147 17 735 60 101M = 499 -336 ACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT AEHFGJG:@GHHIHFI@;>JHHEEH@IJJCKJFJJKMJJIIJJHIJGI=HFHGJKLIEFFKICDIDKBIKE@IIIJHGIKKHIGIDIFIG<IFKMJMBGKDFFJF@CGBBIGINHJEJI?FFBDILDLDDILIFGA7)?EEHLIMIHFIFHHHIFDFJD X0:i:1 X1:i:0 MD:Z:83T5G11 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR229775.92236775 81 17 758 37 101M * 0 0 AACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAA A?>FGG@BDCFFJIJIMIKIMFFIKJILIIKJNIKJILJMJKKMLMLMLMJIIJFINMLFJGLKJKJJHIKKJLJHIJJLIIHDJKIJGIEFGFGHGHDFB X0:i:1 X1:i:0 MD:Z:70T5G24 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AA ERR229775.17900575 147 17 760 60 101M = 527 -333 CGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGA +EGGCFD>EEFAJIIIJHMHEEJJHKIHJIMDCHHKKJJJJMMEEEKMKIBHBLKLKCIJKLIJGHCAGIFDDF>HFHFIHECEGDF?GEB?EFCFEEIEB X0:i:1 X1:i:0 MD:Z:68T5G26 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.83749675 83 17 783 60 101M = 553 -330 ACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAG EEICDIHLCGFDCHH>DFHFKGDCNEKJJLHLLG;KIIIDLJEEJD@IC=D=0GMFLIJLCJHHCHFEHIIHHJHIHDFIHKHGHKH>HHAFDE=GEF=H: X0:i:1 X1:i:0 MD:Z:45T5G49 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.63559677 147 17 833 60 101M = 594 -339 TATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTG FDHFHIHEF@FDD;5AC::ELBGCBHE3DKIHEHMFAHLE=BACIGH>IFB7FEHBC=G>KHFCHIFFGJDHEFFBB@BACFCCD@ X0:i:1 X1:i:0 MD:Z:1G99 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:[YZA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.19017039 147 17 839 60 11S90M = 560 -368 CTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGG ############GJE:GEE?9)D<=B?09>.>/1?ACBCBIJIA@@?5FEEC9HL<<8?7,B?@@@BGHGC9BHIHGI:GG@BHHCFGGJ<3ED;;CDAB@ X0:i:1 X1:i:0 XC:i:90 MD:Z:90 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.98760722 163 17 840 60 101M = 1103 363 ATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCT CBG@;DACF=HDJFJJCMJH@JGIKKIFDFFFHHEGEDHKHGCGJJICAB=?AIIIGGEG X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229775.516742 163 17 845 60 101M = 1152 407 GGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGT A;>HF=GAIHGGH?FIEHGE9EFCIEA=@@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBFH ERR229775.55719080 99 17 994 60 101M = 1282 388 TCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGG BFHIGFHLHHEKIIJKKKHIJKIKILAKLJJLJKJJMKKLJLMMJMLKKNKKMLKLKNNNKMMMKIKMJNKMMMNGHHJFHHIKHIIIKHIHCGMGHDIEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.77830097 163 17 1036 60 101M = 1255 319 CTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTT BIEBGCCHCBCHHH,=FICDJKHCGDGJHJJKHFIIJKLLIKLGLGKLMMDHLJJDLFIKIDIDIKIGJIFHHGFHEHJH?JIIFJFFIIFLIJHGHGGIB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@ ERR229775.3695912 99 17 1042 60 101M = 1118 176 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIHHHKIKGJKLJIKLLLIMMMMMMJKLMMKLMMNKLNMNNKLLJJNLMLKJKJLMKJLJJHKJHHHHLHFJIHHHIKIKINJKIHJIIMJGEHDED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.54641833 99 17 1042 60 101M = 1321 379 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIGGGKIKGGKKHAHLJLIMMMMMLJKLMMKKMMMFLLMNMJNMKJMJMLKJKJLMKJLJJHKJHGHHJHFJIJHHIKIKINJKIHJIIMJGEHDEF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.90795085 163 17 1066 60 101M = 1297 331 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTT BGHGHEDHGDCHJGJHIJI?JGJIHHKIKIGHHIKLIFKIIJIHL=HIKJCIGLLHIHKJMLKIEBEHJMLJDMIJKJMIKLDHKCJJGFDHHGGGEFFCB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:JOOLJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BCEGEE ERR229775.51118640 99 17 1069 60 101M = 1370 401 AAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCAT BHFHIJJHJKIKJJKKLKHLLJJMKLKJJJKLMJKLJJJKMMFJGKKMLJMMKKLJKMNLMNNKLMNKLKLKMKLMLLIGLLIKNKKLKJCKHFEEFCFGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.57580585 163 17 1077 60 101M = 1316 339 AAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTA BGHGEEE@G>9JHEGHGIFFHHHJKHHIFBAIIFGHHIJKHIJKIIKJIKGJKMLJKKNKKBLDLJKLJLKKJKHLIKLKLKIKLFLKLFIJJEIJGHFDE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CFFB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229775.82642257 163 17 1081 60 101M = 1336 355 GAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCT BGHGHH@JEB@JGHHEGGGHJHBJHHIFIICIA>HDJIKJIIJIILLKJLGJJLMJJGLJLGKIHJ=JJKLLMJKKLKFMKLLLLFIJKIKKKKHGGFGGJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@L ERR229775.30538656 163 17 1087 60 101M = 1321 334 CTCACTGTATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAG A?BHJEKFGG??IKKKAEIKJJLLKLLEHKLKIHIJIILEGGEG? X0:i:1 X1:i:0 MD:Z:7G93 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.87113255 99 17 1096 60 101M = 1361 365 TATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTAC ?EFGGFHHJHFGIAHIIFKLLKJKLJJKIJKMKLMMJJMNKJMEHHFIEDIKLKLGLLKLLLLKLKJHKJJKKHKFIKD;JCGEIGDIIDK=4CEDEFAEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.98760722 83 17 1103 60 101M = 840 -363 GATACAGGTTGAGGATCCATTATCTGGAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCA EFFFGLHGHJLNKLKJGLLNLILLLIAKKKJLNKJHJMJNIJKDNNNKLLKNNNJMMJMNNNNLKJIJMMMJIJKJKLMLJJEFHHHCIJAGFFHLDIHE? X0:i:1 X1:i:0 MD:Z:26A74 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.37017046 99 17 1113 60 101M = 1339 326 GAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAA BHDCIGGFIGCGIGKJKIKIJKLIKLKILJKKJFHJKKILJJKKLLMHJJKKLLMIJJKLLLJKJMKMNLLIJKLKKLDFLLKAFHDIIIJHKLGGFFJED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.3695912 147 17 1118 60 101M = 1042 -176 TCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAA GDFGGHIJILLFHHMIIMLJKLIJNKKKIMNNKKKKMKMILMJLMMMMLIEIJMLJJIIJIKKLLIKIKIBGHHKJHGEIKFIIHHIGGHBAEFCDEEEE@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GE ERR229775.17531023 163 17 1121 60 101M = 1381 360 ATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAA BEEEDE@EFDEFGFI>GBCBJHFGGIBGFFEJIFJJJJKEFJJJJJKJIHEJKKIEGHJMMKKHGJHFIKJIKKJHJKKKIHJKKLJKHILGMGMHHIEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CGDFG ERR229775.516742 83 17 1152 60 101M = 845 -407 AATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTAAAAAATCTGAAATCCCAAACGCGCCAAT 7?ABDGED>DDDDJE?FB9DDCEA.=<>AD=/AEG6ABA8FD>2CGF@GFBJ?>5*G>59@.<*4JKIB;D*)JJIIBHA:8GC>=E4;H7C>F?GCEDE? X0:i:1 X1:i:0 MD:Z:72C28 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.36576640 83 17 1160 60 101M = 937 -323 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC ADEFFKKIJIIHIIJGJIHIIFKJJINIHJJJMLHGHJLIMHGLJIGEFJKGFDKGCLKLLKMLHKKKKJLJGIKJIKLKJJIGBKAJHIGHHHLHGGHGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.6073289 83 17 1160 60 101M = 857 -403 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC <@AFFKKIJIJHIIJGIIJJHFHKJHNIJKJHBEF@HGKHMLJLJJJLMJKIJGKGHLKLKJLLHKKKJIKJJLKJIKLKJJIGBKAFEIEHGHLHGGHHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.78971137 163 17 1189 60 101M = 1464 375 ATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAAT BBFEFFBCCB@GHHGHHGDHJJJHIGKIHGJLJHJJILLLLILJGKLMIKDFHLKHAE;@HGMGILHFIJIIFGLJJHBCHAGEGIIKIAG>CEMEGEHHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.87728427 99 17 1242 60 101M = 1483 341 AACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAA BHE>G?HFHKGIKKKIIIKKLLJKKKHKCEJJJJEJ?JEBDMJJMABJJIJKLJJJFCDCGDHGCCHEHGHLEEHFGHC;IMIJHGINIIIGIMHIIGGD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BB@ ERR229775.77830097 83 17 1255 60 101M = 1036 -319 GCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAA EEFFIFFIHHGINJAGKIJJGHAIJGKKMKJLKKKINMJMMLKNNNKMMKNMJJLNMMMNKMHJEALKKFJJJLJJIIILKJJHIIIEHIFHHJJJGGFFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IKMJ ERR229775.55719080 147 17 1282 60 101M = 994 -388 CTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGCATTCCCCTAAGCCCG ?EIHGEHF@HCJHEFEIHEGGGHIGHHHKG>BGJDEFDBGJKDCEJKJHJELJJIJIGHF@KKIKILKKHHHIIIKGJJHJHEFDGLJJMJLLKIIJLMLJMJJMNKLLJLKLKLJNNNNKKHKKLJJJHDHGDGJGGLHGHJIHAGHJGIHAGKIHGJII@FFCCCE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229775.57580585 83 17 1316 60 101M = 1077 -339 GGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTA BEDG?HHKHIJGIKHFHGHKFDIJE?HFHIGJFFFFCCCCCKDEEGFFFFFFFEHDDDFFCJEJLCJIHGLLCLLMKIILK@KKHLKJHIIHKFJHHGHFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.30538656 83 17 1321 60 101M = 1087 -334 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG EEHFDIFIJHIHFFCIFIIIFDGIKJJGGGGDDDDCJDECGEDEFFGECGDDDFGBCACJBGIIEJLCLKMIJKLLBLIILLKKIKHKGKFGIEGDGEFI? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.54641833 147 17 1321 60 101M = 1042 -379 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG FFHGEHEIJDFGBHKIHHGC<4FHIHHFFFF?BDBEI>G>GDCADCDDDI>AAEE@GAAD>FEB@HG8EGHIIIKHAJIHKEFGHEGGEHB;E@BDEEED@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.29727862 163 17 1327 60 35M66S = 1641 363 CCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCGGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTT 7==;A97.8+7HA;IE:88;9EEFH8>;?E####################################################################### X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.82642257 83 17 1336 60 101M = 1081 -355 CAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTC DBEFFGGGIJIKIIIIFFFFFKFHHGHGGGGHD?HEDDFFCKGDGBMJIFJC@MLNMKJLLBMMJMMLLMMJMJLIJLLIILIGIJKJHIIHGHFHGDEGA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.37017046 147 17 1339 60 101M = 1113 -326 TAAACCTGATTTTAAAAAAGTTTGGGGGGATCCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCT :DCCDCJFIJHHF9FFHHMFGCFGGEDEC94#455D@=I?7BADBJJIJBCHMJJDMH?HGDLKJAHEHKA@>B=HDBIGHAEHH8ADDF<8DFEHGEGB@ X0:i:1 X1:i:0 MD:Z:31T69 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.87113255 147 17 1361 60 101M = 1096 -365 TGGGGGGATTCCCCTAAGCCCGCCCCCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTATG FEFFGGHDCHCC;HIF?15;7A:4#FD>JKG@DGMKBFLFKLKAJ@AMEE9BEBB:GFB?CIEHGJA<>DDH=BJEJIBFGJAF:DGDMIIMJJCKLLILLILKHIHKKKIJKHHFDFHKHIGHHFFJGEGFIHBBEF@FEEGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.48996859 99 17 1381 60 98M3S = 1659 345 CGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCT A5FEFEGF?EHHIEIIH8HIIJJIHLJIHGIJHMJJJNA:FAIHGML;0GEDGILGHKHGKHHIKINJKLIJGGFFFF8FFLJJIFEGHLKJGGKMLILLLJKKILKIIILEKHFJJIGEE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR229775.87728427 147 17 1483 60 101M = 1242 -341 TTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCT :=;FCD?1/EECJIGHCF>AAFGCIHKEA=BDAF<:EB>JFJIDBHHCHAD>+#AFDEIE?B@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.15144424 163 17 1542 60 101M = 1799 357 CCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCT BDIECGEFDCEIHBGCGHGGGJEGHBIFHDJIGHJKJIJJKLH?K@JKFJEJIHILMFJMMHB;>IHIIIMIJCKKIFJHGFHJDHGMFIIJG>JFHBDDF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.83025798 147 17 1590 60 101M = 1304 -386 CTTGTGCCCATCTGGTGACCCCTCACCCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC CA;4I?C?9HGCJEBD<08@2J<+=@=DB9CD@ X0:i:1 X1:i:0 MD:Z:26T74 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.29727862 83 17 1641 60 51S50M = 1327 -363 CTTGTGCCCATCTGGTGACCCCTCGCTCAGCCCCCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC ####################################################E==>=55;,C:65/9:=5J=C>FF@=GBJCB?5"D1?L;1=EHG;=BA0 X0:i:1 X1:i:0 XC:i:50 MD:Z:50 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.107364540 99 17 1651 29 101M = 1920 369 GGCACCTTCAGCCACGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAA ?CGGDFL?FHCGFFIAKJIIJGIEHALLJJKGCHGEIEELFIFHMGFGIJDFMFKGIJCMEKHFEAHDF X0:i:1 X1:i:0 MD:Z:14T86 RG:Z:ERR229775 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBF ERR229775.48996859 147 17 1659 60 33S68M = 1381 -345 GACTTCCCCGACAGCCCCCAGCCTCGGCACCTTCAGCCACGGACAGTTCCGCCGGCGTTGCCCACTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCC ##################################G=:?F3CCE>D:8=64'#)'I<=):7>HIB@=A:CE1;:C=JJHC9A:<7=BCFHCL@LHEHIEHA@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.69874320 163 17 1704 60 81M20S = 1920 309 TCTCTACCAGAAGTGCCCTTCCCTCCTCACCTTACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCCGGCACAAGCCCAACCTGCA 74J?@C:D@-=C;696/*=;DD8+@*@7C94='04*65:A@860;+9H##################### X0:i:1 X1:i:0 XC:i:81 MD:Z:32G48 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.51562629 147 17 1727 60 101M = 1445 -382 TCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTG ADDFD?GHHEBGIGIHIJHHHHGGHGFEGHFJB;2CB?FADDEAJDDFC@8ABCE?A@BCACCB@H@<AEGG@HEG;ACBGCHFFAFF/?GFJLHILKLHIGGIJM:CECFEIHLBFIDJEHEHILAHB5CFG@FGGLHHHGI3?FFILIHHMHGGKC6C X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GAA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.2494821 99 17 1749 60 101M = 2024 375 AAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGT AHHGFFFLHHGIIHKKHHJKLJKLKJJJJLLMJJJJMJCLJJJNFJLMKKMMNLMKLNMMLMIMHKJHJGG@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@FC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.15144424 83 17 1799 60 101M = 1542 -357 CCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCATG @BGGGGB8D@HEHKEJFGGGACGCGKFGGF?EGCCCCDDCGEEFEIGFHDIFJEGGFJDFEBHCEFGEGJKE>LLLKJKII@KKLKKAIHFIHFHHEGFHB X0:i:1 X1:i:0 MD:Z:70A27G2 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@Z\V ERR229775.97978507 163 17 1893 60 101M = 2135 342 TGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGT BEFCHHGIEFJDFKHGBGCFF7CAD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.107364540 147 17 1920 29 101M = 1651 -369 AGTGCCTTCTGCTTGCCTGCGGCTTTGACAAGAACCCGCTTCTGGTTATACATAAGACAGCCAGAGTAGGTAGTTGCCCAGGGTGGCACACTACGTTGCTG <@DE96DJHGG>8CG@:?4$=@*IBB@41AEC<=3+#(B<@6F=287JIG?C8(A@BCIH>MLJFH?C;CJIFGCGDIBIJHDCJCEFFHHIHD?ALEC5CHMD38CECLGCE?45HLCE;BEGFHGJ<=C? X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.43533499 83 17 1932 60 101M = 1693 -339 TTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCC 2D>ADFGGIIHFIKILIFLDB51FCBHGGCKJILFIKKJKKJMIHJMLKJMLMJHLIGIMJMKJGJHGKKIJHFIIFLDHG@HIFIGGGH?KCEGHGGF?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.22929983 83 17 1950 60 101M = 1693 -357 AGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAA HEA>CFFGIHKIKIGMKLKJIFKKMEIKLJHKNKMKKNMMLNKNKMJCLMMMJJMMLJKMLHIAKMJLLJKLKMJLJILJJKHHLLKJIIFKGHHHGFFFB X0:i:1 X1:i:0 MD:Z:91G9 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ADB ERR229775.66105707 83 17 1971 60 101M = 1746 -325 ATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGA EFCIGFCMICINIMIGJIKKNBJKIHIKMJJKKLJIFINLJKCKMKLMKJJGMJMIGKJHFHIMMLKJIIMLKJIIKKJIIKKKKHHDIIGIHLFGKF:FB X0:i:1 X1:i:0 MD:Z:70G30 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.105154648 163 17 1981 60 101M = 2189 308 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGC @DCE:EEFD<=H?>>?FF==CCB@1:C=FFGHG;<=?HKICHBC?4AFEE:HEC5AJ3B;H?A>6BCEB85 X0:i:1 X1:i:0 MD:Z:60G40 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.52172354 163 17 1982 60 79M22S = 2196 314 AGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAAGAACAGGAGCGACCGCACAGGCT A@?:E>31<61E<;88BG,%/C8/4BAG4;BA1AG92D;D?C9<=)?>;C?BDF+9D+0>>0;DGJG####################### X0:i:1 X1:i:0 XC:i:79 MD:Z:59G18C0 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.39805220 163 17 2022 60 82M19S = 2315 385 CAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGAT @94EAE@J>:3GGEGCGD9=ECACGGHHHE;HHB?DFC1E:AA@AJJE=@C6=43>@CI?8DBC#################### X0:i:1 X1:i:0 XC:i:82 MD:Z:19G62 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.57143597 163 17 2024 60 101M = 2298 374 GTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATAT @DAECIBEC@AGHEICGGIHJHGIEHAGHEDGICFLHILJCJ8FDE>KDD3;C?CJEDHFGEGFCF=F<>>EBIE@DECD?>DB9BECBHCJDADD;AE@;>C>HLEFCDH>IILJ@G6IJGG:AEJACCEEB@ X0:i:1 X1:i:0 MD:Z:17G83 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.11251161 163 17 2065 60 101M = 2333 368 GGAGCGACCGCGCAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGC @3B"2=<"5?9=JGBBB'=:@;DFC=?698AFCD4;74C@EBD7IBFHH8AD@G+-3HGHFHF>IIKJKIHKBKBLJLLLLJLLJKJJJKJJCHJKJLHMMBLHJJIGIJGI>HFCFGJKEHGFHIFMIJMIDMIIMIHGHADFFIHKIGHEDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.18301321 163 17 2092 60 101M = 2301 307 GTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCT AFEECE789<',AD@GF@BG?>H<4F7GBIE=@>FCF;=;CEBFE>D=A=AAJGHKH;DDFKHG?C02BAIHG@@FEAA3=6 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.97978507 83 17 2135 60 101M = 1893 -342 TCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGG E=FGGHIGKINJBIJIJGMIJFMIJHIHJHHIGJLHJJIILFNNNLMLKLJKJGMMMLKKMLMKKJLLLLLJLLLJKKJILLKKJLKJJIEGGGHHHGHEB X0:i:1 X1:i:0 MD:Z:85G15 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG ERR229775.15256528 147 17 2147 60 2S99M = 1898 -347 AGCGATTGTCACAGGCACTGCTGCTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATC ###E?E<9G=8IMIIFGED<9;(BABBB;8;99?ABIGDCHJD?<:;C7FBEE3EBHDG9@CCKGHH@??D@;HFG>1EEF=BCDAG9631,D9DE@7 X0:i:1 X1:i:0 XC:i:99 MD:Z:20A52G25 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.75821297 145 17 2155 37 101M * 0 0 ACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATG EFKFHHIIJIIH@IKGIJHHHFLLLJFGJKHJHEIIMJJKMLNKKIKKMJGELKLJKGHGLLKIJLKJKIJIKKIHHJFJJHHHHHGFGH<;DEFEIEEG@ X0:i:1 X1:i:0 MD:Z:65G35 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.105154648 83 17 2189 60 101M = 1981 -308 CCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATG ?BEHFGKILIHGFFGDFGEGFBHEGKHNLFJNLKKKLILKKIKKKLIFJCKJJJJLJKJJMLMJIIJJICLLJJIIJIIEHJGGJHIFHIIHDHFFFEFH? X0:i:1 X1:i:0 MD:Z:31G69 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.52172354 83 17 2196 60 101M = 1982 -314 GAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTT EHCBDDB?7=E=DBAKCDGLHHEIMICHKJHAKKKK>CDJIJIKMGFJKIFFJMLMHIIEMJKMDHIJKJKJJJIIJKIJJJHJHFHGFIJGADHICGHJIJKDIIFIJCGEDGBD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR229775.59500924 99 17 2276 60 101M = 2490 314 GCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAAT &HIEGHLHGHFIHEKIHKJLJILJJLLKIIMJLLLJMJIHMKKJJMGFJJLCLIJNJKJLJGHGJ>G@@GJGHIHKHJJFIFKIKIKGIJIIIMHAEFGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.57143597 83 17 2298 60 101M = 2024 -374 CACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACA ?EDFHFHFHHHEFJJFIHDEJFHHMEIF@KOJJJNJKMJMKL?JNMKLNKLMLMJJMJMMKJLCBLJILJLJLKIIKJII@JJF?JIFHEFKFJHIGGGFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.18301321 83 17 2301 60 2S99M = 2092 -307 ACCTGTAATCCCAGCCCTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGCCCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAA ###GAB7.BC><:*5'=GG@A:?H@A8,@B77FE-EIEEEHBDBKJDH=IACICBGGLLJHH'%/HLJCHICICFADHA?E?>:B?I:FG=EI:@@=ADC? X0:i:1 X1:i:0 XC:i:99 MD:Z:13A47A37 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ED ERR229775.39805220 83 17 2315 60 8S93M = 2022 -385 TCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACA #########DFBIFEJB?%?I@FFIMFFGFFFD;DLMJEJ>8FGMHGHBMKHFM=/GCJFJKEKJCFJD8JAHHIJJIIIDII@AEJFGHBGHHHHFEHC? X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.12020490 147 17 2330 60 101M = 2089 -341 CTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGT EFKFGLHIEHGFHIIDDHHCIAJGBBHDB;=+EB@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.11251161 83 17 2333 60 101M = 2065 -368 GGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGT BA,>9DHC@BEKKIKCAAGKFEGIIHDCJHEG?IIFKJDEFFIMHKIDHDFFJJJIIICEEHJJIJJIJECIKJJILEI?FHFDGEEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.80729707 99 17 2417 29 101M = 2698 358 TAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGA :EBE?HH>CECHH;>?IDEFLDGNIJIGHG@B?AGF@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.101859832 99 17 2474 60 101M = 2762 388 AGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAG ?ECGDLGFKGCKHGKKIGKGHGIIIKJEILJKLJFJ@EHGH:CHJL?HJHIJHMLLIJIEFJKIIE=HB>HGJHJIBEH>GGJHJHHFMG;H?FCHB6>CA X0:i:1 X1:i:0 MD:Z:90A10 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229775.59500924 147 17 2490 60 101M = 2276 -314 AGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAA IEFKEGJJIMIIDJJIJGJHMHHIHIGHI?HHJLHJJJLKJMKGJMKJI?DJJKJJMKLJIIKHJFCGIFIFJ;KIIIHKJGGJIHHIGGCB@FCIEEEEB X0:i:1 X1:i:0 MD:Z:74A26 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEC ERR229775.5983641 147 17 2506 60 101M = 2267 -339 TGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAG GDGGKHHJGGEIKAGHHKIKHKJHKMKEGNJJ?;LIKJJCJJNGJKLHKHCJHFFEK>GJJJJKFIJKIJHJIIIHHIHKJGGHGFHGGGBBEFCEFEEI@ X0:i:1 X1:i:0 MD:Z:58A42 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.52727770 163 17 2538 60 101M = 2848 395 CCGGAGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGCAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTT @0=>12?7?C;8I=0;9>#AH@ECA9=9=0().D=:;CKBE'450120:7+@C=E4C6E@CE5ACFI@D<@>9G=?;?E*=3HEKKJJCHKKHFHGJKLIILLGJLLLJJMMJJIMMMJJMHKKEEJGKLJKMLMKJJILKGLHJKJIIMIIIMFFIGIGGKFGE X0:i:1 X1:i:0 MD:Z:17A83 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.18618553 163 17 2570 60 101M = 2828 358 GAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCT @>DGC8=FEC>CGDIEHCACFGFKKAFHKJBDDCJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229775.83543817 99 17 2577 60 77M24S = 2821 288 AGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTC 4::A:>A>G8)>F<>ADDHDCGAJ<=JB,*EB797,>HHL@C95=/:EC=@@FC>GEJHC=479788BI96F0EKK######################### X0:i:1 X1:i:0 XC:i:77 MD:Z:77 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.66162627 99 17 2602 60 101M = 2766 264 AATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCT ?DFGEHGFHIHGJEKKGGJJLJKKJLLIIKMIFHMJJIIJLLKJJIJKHJKMKFAJLJKLJKGBHJIFKGHHLHIJMIIGF>BCGJGKDCJIJGGFKFIEH X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J ERR229775.36854728 99 17 2628 60 99M2S = 2910 357 CATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGG 4GFEJG@EKG=@.BEGJ+AHFCFCGLGGD/E9CGADGFH?GDKGLFIAHDJ@BHGLEFDGEE=DDGIBFB### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@@ ERR229775.80729707 147 17 2698 29 23S78M = 2417 -358 TGCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTATGATTCAGCTGAGGGGTGCCACTCTTACCATCTAATCTGTGCGCTTATTTACTCTGCTTTAGT ########################HI<4*16J>9**D?/?:9**HC)F3A'6B3F/;1.(((>/2&-5=*;,3HA<':0+('/(;/*7.(7%;'.2C@481 XC:i:78 MD:Z:15G3G15C21C7C12 RG:Z:ERR229775 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.94440410 147 17 2716 60 101M = 2419 -397 TGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGAC DEFJHGD>7E>ADGG@:9HJBIEADHGGGIHJJFGA>A?99DEKGFCC=4<%DGG;@BCCEDDF### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.45483038 99 17 2750 60 101M = 3055 353 TGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTC BFHGGFFLHHGIIJKLKKJKLJJIHIKKMLLLLLMFEKMMNLMJLLJJJKMIFCFLILKLLKMLNLICHBEJ3AFAEEKCBCDGFIF;?=CCHFFEEC83; X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.78014576 99 17 2757 60 91M10S = 2948 291 TTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTC BFGGGHGFKHIIIHIJFKHIKJLILLKLJKKMLMJLFJLJJJLNMMMMLMMKLMKMLKLJBJJFGCGFFECGHFB@HFFF/7@67?9E@F########### X0:i:1 X1:i:0 XC:i:91 MD:Z:91 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.101859832 147 17 2762 60 101M = 2474 -388 TCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCA <8=DBIGIHJGIDJIMHICFA?BGEFAG9FEGAAJ@CC?@DCFHAJ>>811?C;85FEHCBHA>@K8EE=3@<@EHB=;HI>FF?EB@FF=C5CBA@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.66162627 147 17 2766 60 101M = 2602 -264 CTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGT EHGCA-@LEEDGHEFLEMHB?B?@FGEIDG?CA?FC>ACD1??@;AEAGCGGAAJKGFHK=IEB?LGCEFFHDCG#:3?EBFBGDF X0:i:1 X1:i:0 MD:Z:90T10 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.44852854 83 17 2817 60 101M = 2547 -370 GGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGA BCC?6ABEHFILIIJJGGG;IGIHMIHIHF?EH?HKHLKLKKMMLNMMJKKMMKMKLKKNLJKKKLMMLIKJLBKLJJLLLKBIIKJFKIIHHHIHKEEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.83543817 147 17 2821 60 56S45M = 2577 -288 TCTGCTTTGGTGAGGAAGAGGCCCCGGGTCCATGAAGGGGCCTTTCAGAGACGGGGGCCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGG #########################################################7,,/?4:@2;'B6#'01'8,2'4&8.;H29?@:+&'-13CH;-1 X0:i:1 X1:i:0 XC:i:45 MD:Z:0A44 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.18618553 83 17 2828 60 101M = 2570 -358 AGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAG #B7@??990GHIIMFDEICAGH?FHCD<+@FEEHHIIIJILKKLKJKLNLJKKKMLMMJKIGBKIJJMMKK>GJLKJIKLLIHEJKJJIKEHGHE@EFDK? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.91229453 99 17 2831 60 101M = 3084 353 AGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTC ?CGEEF?HBGFIGFKJJABI@JIIIKKJJLKJKLLABEHLJLLMKKILJJJJFKKHGFLI=DD?BGFEG>@BBFIJKIKGIHJIG@HHHFKGEF:E7 X0:i:1 X1:i:0 XC:i:86 MD:Z:86 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.7004516 163 17 2878 60 101M = 3107 329 ATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTG @EEFECDFD;:JG0C=?D;AGJ?GGGJEI<=JHHHHJKIKE>CFIKLGGE?HIH6?CAF>GBKBA9GIGB?EDFE@IHGFGHIGEFFJG:@FIC@EDB?6B X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.36854728 147 17 2910 60 25S76M = 2628 -357 GGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCA ##########################HHKC9,>ABC?;DBGAH=8;;IEE<>2?HB@C>HCF7<;2G79===)C@5&=*B@86FEEHA@B9:<797DB3;@ X0:i:1 X1:i:0 XC:i:76 MD:Z:76 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.28172972 163 17 2918 60 101M = 3194 376 GTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGGCCAGCAGCACCCACAGCAGCCA BFECEDAFC@CGJH?GIIGGHIJIIGJHHD;A;@=D@9BE>:D=BHI9;;A"99>><@>BCEEE=CFEFIBAC# X0:i:1 X1:i:0 MD:Z:78T22 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.78014576 147 17 2948 60 101M = 2757 -291 GCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGT C@AB=GIC>BDHFFG@@??HHFHGEEIGHHHFBCFFIHHDJJEFMLHJKFEFHILEF>IHGGIIHJIHHI?EKIIHJJEJJHEJIDJHHIB@ED@EFEIDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.19870548 163 17 2964 60 101M = 3254 390 CACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCA ADDECGIGHJHBFH:F=:<9D??FIKJIGJHCHLGIHIEABDE@CGDDFFAFA?CDE@E9B?6>4B@@FAA6E6@5*>1=B>DB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.91036639 147 17 2967 60 101M = 2776 -291 GGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGAT 53AFE?BAHGJIHIBCCEDIGIF=GGGGHKCFKF@F=?CGLJGBKIIKGG?:IJJJJKLJKLKJLKKKIKHB@HICHBHKHFEHGFJHGFBCFE@CEIFEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.11173812 99 17 3034 60 101M = 3333 399 AGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATTTGTCACAGCAGGTAAGACTCTGCTTTCTGG ?CFKBHGHEHFGHEIGDHHILKLLLMIIKLJJKIJIKILMMM>JIMIHIMJFCDJLG0ADIHIGCGDEHHHEHIIKHKHGJIG8GKHKGNIMIIKGDFCEA X0:i:1 X1:i:0 MD:Z:70C30 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GF ERR229775.45483038 147 17 3055 60 52S49M = 2750 -353 GCCCCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCAT #####################################################A54-7=90;?5::24>EAB?DH@DE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FJ ERR229775.59323675 163 17 3154 60 101M = 3389 335 TGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTG @B?ECD9@8@GCII88GHF<9:FIIILLLLHFJEHHJJHIJGKJGI?@BJJJJKDB>DKDJC<@EEBHFLGF?EIAGEHCCD@2ABEACFHDCC#9@?###### X0:i:1 X1:i:0 XC:i:96 MD:Z:91T3T0 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.28172972 83 17 3194 60 101M = 2918 -376 TTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCA BDFCHIEIJGKDHIJHIJIMHGG?IHIHJHKHJJGCGFKBMKMKJJLKLJJIIJFJMMMKMMMLMKFHLMKJJLLJIKIIKGDKLIKKIGHHKFGLDIHFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ABA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229775.453972 81 17 3215 37 2S99M * 0 0 AGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT ###>6FEBCCE@HGDIIHDG?GEIICHHF@FBBIGHDFFF1JMLLLJCIMLIHFLIHJIJFGE?KLJMMHCDKMLLKJLIIJEB@KJKIEGIGHFHBFEE? X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.41226651 99 17 3242 60 101M = 3478 336 TCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAA BFEEGHHFGKGIIEKJKGJHIJIIIIIIEIJKJKJIMKLLMJJJKMMGKDCIJLKLGIJFIGHCBFDHFEIHBEBCKHHDHHI?GIJJGNIHHJGDGEGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IIK ERR229775.19870548 83 17 3254 60 101M = 2964 -390 GGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGC DEFIFHBEIIIDHFIGKHGIKCHIGKKOJILHMJKNHKGJIEKIMJMJDDJIJGAKKLKKLKKMKJJLLLCIKJIIJIJJJJHDEJIIIIGKHLHFGGEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CCA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.43420834 99 17 3270 60 101M = 3494 324 TGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGGGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGGGGCGCATGCCT ?ECHGGHFKIBJHJFGHKBJJIJKJMHKIKJMLLMIJKMKNKKJLI%@GMKHILH?EEHFAJJMMMDFBDIJJJGHGJDDHLDCG;HDA#77=FIJFJIJ=JJIG;EJEFBIKKJFE:GFD8/9:*E@EE3%DJ;D2BDD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:IH@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.94803111 163 17 3384 60 101M = 3606 322 CTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGA BIEECCDHEBEGIBIGIGGHJIJHKIJKIHGLIJLJKKKLKKJKKJBIJIEJKJKKKIMJKHLEFIF@HFGDKGHIFLHHIHIHMIGBGJHGJIJHHGEFG X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.91011602 83 17 3387 60 101M = 3102 -385 GGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTC DDFFKHHFIMIHIJKGLIHIIHKIGJIDHIJKIJKNLLLNLKCKNKMJNKKMMJKKHNMJLIFAJJHIHIIHGLKIGJKKLIKKKJIHILGKFHHLEFDGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.59323675 83 17 3389 60 101M = 3154 -335 GAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTG A5IGFFHGIIIJKINGEGIGI;KHE?1IHHJJKMJJHMKJBKNKMJMHGIMJIJLKJHKIE?GFFJKJEFEHKEIKIEGIFHC;AFHIGL@HHLGIGHDH? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.5896825 83 17 3415 60 101M = 3144 -371 ACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCAT @>>ADEB1CA>FB277FJIFJ;=B18+/A098D=55?==:<>(;0=7BBH@>BEHFCBBC99?JA6@G7.A;?:7:AJGJJJJIJJIGIIGGIFHGEEFE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229775.43002343 163 17 3466 29 43M58S = 3687 321 CCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATAACACCATTTTGGCTTCAGAATTCATATCCTCCTGCAAGGATATATACGCGAGAAATTA 58=>BB1BB659IJHIGHHF:IFBBBHBFAG?G@HFCF;AGFDG>:AECFEEGAA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229775.43420834 147 17 3494 60 101M = 3270 -324 AAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAAC A9>D?@DFHHFFG9?577GHGD;IIGHGIGFKFFGDEBGACABDIB>I?G?HGKICIA9F<=>9>IGIIHJ@HIKCDDHGG<>GGCGCDJBBEFCFFEC<@ X0:i:1 X1:i:0 MD:Z:93G7 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:G@CICDGHJIEDB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BC@CCB@@@ ERR229775.98041640 147 17 3494 60 46S55M = 3175 -373 CCCGCCCCGCCACCCCAGCCTGGGCAACAGGGTAAGCCTCCGTCTAAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGA ###############################################?DHGJJJHE?HD9;D;0@HD?:J7>:5>8GIIJHFGHJIHIIIINIGMIIGHFDED X0:i:1 X1:i:0 MD:Z:57G43 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.98929975 83 17 3553 60 101M = 3302 -351 TACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCT A?>E?FIIFFJKKIFNGKIKJHIHIIEHJHLHDDDCCKJCGJJJKJJJJFFBLJKIFMKMJJJLJJJFLKIJIJJJJK@ILLIILIIFGKIKI?GHGKGEB X0:i:1 X1:i:0 MD:Z:34G66 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.105205152 99 17 3562 60 93M8S = 3856 394 AATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTT ?D>?9HF>@ECDFDCDF;HBDCIID9797+7.7B>6=HL######### X0:i:1 X1:i:0 XC:i:93 MD:Z:25G67 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.30258628 163 17 3583 60 101M = 3859 349 AGAAAAAAAAACATATATATACGCAAAACAGTATCCTACTGTGTGTGTCGTTTGTTGTGGTTTCTACAGCTGTCCGTGTGATAATAATTCCTCTAGTTCAA @@GCHH;6=>ECF=G4D==2BC*:=)6)'/-/4107;+4+@=E7,CBC:;C;BLB?HDGGB X0:i:1 X1:i:0 MD:Z:4G22C31T4G14T21 RG:Z:ERR229775 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:OOVRWWJELKO@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG ERR229775.15284212 99 17 3585 60 88M13S = 3809 324 AAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAAT ?DEDDFFEIECHI;HHHAHI>HGLLGKIJGHFHCJIHEAGF:FJJDC8GIDFJBCFBHDGGH5GCFCBC=:AF/1826-7FJEIJHI############## X0:i:1 X1:i:0 XC:i:88 MD:Z:2G85 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:MRSRRTRPQ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.15906182 163 17 3598 60 101M = 3862 364 TATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTA BFEEEE@EKCDGA@>G@D?HJIIC;?=CD@JK?#;BJJ5DECBIABFDGHHCGFE?DJDGJGKDGI5BEIKHFFIKD-BHEFEGMGIIKGIJJIJGJGJDJFJ?FMMKHNKIKKNNNLDMKLNLKKKLMCKKKNKKJLKJKKMKLKKMJMJMKKKKJLLIIIJJHJJKIHHGHJIGFFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.15603458 163 17 3626 60 101M = 3846 320 TGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTG @EADDC9A@B@GH@GBCFB>>3CD?=;E@9>H;C;IJBIIIIIJIJHILHCBAF;=GI@BJDJE>>CFHKHIINE:BHIGH4E?EHJGG>AFMIFIEHAJ4 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.80842527 99 17 3639 60 101M = 3844 305 GTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTC AGEFGHHG?JEIHJLJIKK@IJJJIJJMJJMJKMKMMMJMKKMKNNKKLJKLMKKLKLLKMKNLLKKKNLKKMKJJLLLLLJLILIPLJKILJIIGHFEJD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.84503264 163 17 3670 60 101M = 3903 331 TTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATC AEFCIEFFEB,CEHH?*;6936?956.-2%7)=C@3?BB.6C891FDGFJ?==>D@A:/DEB5@4BDG@D@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.78993145 147 17 3760 60 101M = 3530 -330 AACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCG 1@DGHHHFIJE@:CKDGIJIFHJBFBFGIHJJEFCHGEKEIIHGJGFAIKDJJMLJJIILDKIKIKIHHJEBBAIHJJE?HHIGGCGHHGABEHDEGEH9A X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.102280357 83 17 3772 60 101M = 3516 -356 ACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTG ;EGFFHIFGIKIKGJIHGHJIDGIJHIJHIGGGHG>HLJJJNIJKKJMJNKLMKJLLJJJDCKKLKJAIGLJIJGIJJLKJLICJGJAIIIHKHHHIGHHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.60297548 147 17 3785 60 101M = 3736 -149 GTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCT @GFFFGJIJGIIHHKHJHHIHF@FIHIJLIHIFFJHJAGAIIHDGFDGAIEGHIAIKHIJIJKKIJKGKJD@IIAJKKEKJGDDJCGEE:,BJIGFGEFHFEBALJGJ?K4E;KILICFJELIFKJB>AHAF@HFGEGGGC? X0:i:1 X1:i:0 MD:Z:90A10 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.105205152 147 17 3856 60 101M = 3562 -394 TCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTC #BE=GGHILIIHKHHJGJHJDHEKD;+EBF?C>FFJ?E?DCIFEIGB>=HGBDILKGIFB>FI=9*=<><'?;C69?8,6?DD253-72,D9>: X0:i:1 X1:i:0 MD:Z:80A20 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.30258628 83 17 3859 60 27S74M = 3583 -349 TCGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATAT ############################FLLJHF-.LGLKHKKHCIBLHBHDB?@@;7IH=9>7/5HIE+A@EHICFFIGIJ@AGI?>KHAGEFGHE:DE7 X0:i:1 X1:i:0 XC:i:74 MD:Z:74 RG:Z:ERR229775 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.15906182 83 17 3862 60 101M = 3598 -364 TTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGG FEFFGGJHCKHHKKGHILFE@:EBCFIIHLEHHIMHEEIFBEGJJJKIIBAIGJMMLMMJMIIJIJKJJJMGLAKAKFFEJIDGHIHCJK@GJJHJGGHEB X0:i:1 X1:i:0 MD:Z:74A26 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229775.104583040 99 17 3884 37 84M17S = 4097 298 CTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTA ?HFEEHFHBC7EGAHIHCHFDHL?HJ=FI48C>KFJL=EKCCJJJALKHJLJLLIIHJFKHIIGGKJHCG?EFBHIGDCF>F@CCDFEGEGFF@ X0:i:1 X1:i:0 MD:Z:39A61 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229775.84503264 83 17 3903 60 2S99M = 3670 -331 GCCCCTGCTACCCTCCTTCTTAGGGCTGATATTCCGCGCCCCTGCTACCCTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCT ###?DDA5-;91@B:HBJ<:89-=F65868-%4C9E5-=>9C+9C9H;AFC7GEBCCJJILKJHHAIHELLIJJD=C>IFEIIJIJHLEEGEB X0:i:1 X1:i:0 XC:i:99 MD:Z:0A8A23A3A8A52 RG:Z:ERR229775 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ bcftools-1.21/test/mpileup/mpileup.4.bam000066400000000000000000000641021467060157400202150ustar00rootroot00000000000000‹ÿBC×ÁJÄ0E3¸z]ù%ò’ÖfÞ[µJHb¦A·%íLq@gDôý2ã»:pát­Ûý !š±‡WÏò!>óz»}.×ô}.šx„˜…ë¹Rˆà9QÂzMH«”RïéDJ«r[¶’ö ·ÚÈþЙRC <þ|¤kÑL˜žŸ¦I)ÒºÛñ8 JT³™—uþ<¿_–Y¢$ˆ.+ú‚áŠ4<»`ÜÁ²±öÅßB9N!_(ªŠ]®¸Ë“Z¼Ý ñn;ÛÙ‹ÿBCONÕ½{Œd{~Ö3w^=Ï>§Owªóü½çœêë~?,HúÔÔ½S»xí]ûڬ׻öîÝ{÷¾vc³1ÓÅÁ[Æ­C,À!‘7!/Ë1FL‰X‚Ä’#À‘‚%ÁÉ?È‚DÄ’EòýüªUÕ53=“Ü™NÝéªîªêÞÕç|ëóû|ß_¾²pz[N>á_]ø¹…wþ:}ý÷ôõÆw÷ææÁÞÞîë››ëÛû;[ ×®/,|š~5è hGÖ†5ë×ýa8车®ƒ~Í‚ Ï¹g‡£†y½‘e܆ö 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Π@ØQ’T¦–Y+U%iŽÌJ5F‰ J•*…I$ÐÏp÷$@øéUݵh$føŒF °1AQ™TFjždS¦¥bN¸kŒfÛ6GôybZ”ä`²Fkv´ûï¾›]ÿêbx˜Ã­·RèÈg»%‹ÃeEOõ½¡Ýç~o¯ß§áÚ&Ž˜ýzÞž?;_ÏÞ}ܽ˶È z´F‚)’Rª‚#éplpBÝ£.åß‚ão鑹œˆà¢áno3¦DÌF‚ 07Lïš r§¸(ceR6¶ÔÌá$3%²p¡_ì~mX´ïóní¸¿}Ý:qÉšv 3!v Ôšž˜Jæ”d¦hkeIêG¦U•’™•b‘°ÝOxXDŒã©Û‰‚&,çí‹u?Æî®ãS~îvÌA7Fß7DŸ¬ zßÛåóvßï·ñz9Þÿz=æüõòûëÛ¯¿æe¿>ýàU‚ýVQ‰L öBÇìÇyÞÞˆí²¿}íK; î êlÁcO´0ØuÚ››{„0È °ÜΫõá$Ê.˜Ñ»…¤${ch­ZK‹•’VTË–î&Î1”gHP¬p38úx³h |¢hs>¿=]µYŽ!©Ý}NU×»KBè!rr´kêüz¿×äÓÿL³H‰ñˆˆ1 !¢¦R`TúX]äʬ”èY Kk‰ª”JÒÊ'ˆá‡Ïf=(ÂÝ!ñÂ{·qªùùm¥·½*U‘'ȈFæŒ9|÷sŒéîçÓÓÓ1g{ùz»ü<û]÷ƒÃ9÷ûõýòuó×—÷×÷¯ÿz{ùºí—ñå2.¸5oa} ‰•aU”æ6vº‘¢Pfaýÿ;·$[·\ ƒh‹ÁAAÄ°¡æòÚ?–ìE¢œ„ÓmαŠš¬%加!*ps[r›Û’7·%çêv€·v pB›ŸÖÄcœsŽµ]l>ƒÔ­Éb›n´á†c9ÝNwn-•¹ZøÌœä‡pS © 7ŸüÎÝÎ!tÉé¤ÈÐDÊÌLrR±£Ã›Jrš#†MºÍ«[n®G¤&âÑ5[sÞ\n«EA”O5eAn“{Î'’$½š³Z”­œÄåIRt­¤¢È­ÕVHWÙCѶVCZ!ùìŠytˆ²§Ü$ØdL§K(ÆflœšOŠé*AªA:mŽ›¶¶sŽ6Ýl¥ÍµæÊ͹cSLt9.ï7©Zÿh ÿÿÿÿàEOFbcftools-1.21/test/mpileup/mpileup.4.out000066400000000000000000003360531467060157400202740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 100 . C <*> 0 . DP=18;DPR=17,0;I16=16,1,0,0,672,27586,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,189:9:0:0:9,0,0,0:9,0 0,9,118:3:0:0:2,1,0,0:3,0 0,15,134:5:0:0:5,0,0,0:5,0 17 101 . C <*> 0 . DP=18;DPR=17,0;I16=16,1,0,0,630,24730,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,182:9:0:0:9,0,0,0:9,0 0,9,108:3:0:0:2,1,0,0:3,0 0,15,132:5:0:0:5,0,0,0:5,0 17 102 . C <*> 0 . DP=18;DPR=17,0;I16=16,1,0,0,676,27812,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,188:9:0:0:9,0,0,0:9,0 0,9,121:3:0:0:2,1,0,0:3,0 0,15,139:5:0:0:5,0,0,0:5,0 17 103 . T C,<*> 0 . DP=18;DPR=16,1,0;I16=15,1,1,0,668,28542,6,36,929,54841,29,841,323,7035,6,36;QS=2.98256,0.0174419,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64924;SCBZ=4;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,17,184,24,187,185:9:1:0:8,0,1,0:8,1,0 0,9,118,9,118,118:3:0:0:2,1,0,0:3,0,0 0,15,147,15,147,147:5:0:0:5,0,0,0:5,0,0 17 104 . G C,<*> 0 . DP=18;DPR=16,1,0;I16=15,1,1,0,601,24163,3,9,929,54841,29,841,320,6884,7,49;QS=2.98726,0.0127389,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64309;SCBZ=4;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,173,24,176,173:9:1:0:8,0,1,0:8,1,0 0,9,101,9,101,101:3:0:0:2,1,0,0:3,0,0 0,15,133,15,133,133:5:0:0:5,0,0,0:5,0,0 17 105 . G <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,603,22351,0,0,1018,59282,0,0,325,6815,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,171:10:0:0:10,0,0,0:10,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,125:5:0:0:5,0,0,0:5,0 17 106 . G <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,636,25058,0,0,1018,59282,0,0,324,6718,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,190:10:0:0:10,0,0,0:10,0 0,9,92:3:0:0:2,1,0,0:3,0 0,15,124:5:0:0:5,0,0,0:5,0 17 107 . C <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,686,27952,0,0,1018,59282,0,0,323,6643,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,192:10:0:0:10,0,0,0:10,0 0,9,119:3:0:0:2,1,0,0:3,0 0,15,136:5:0:0:5,0,0,0:5,0 17 108 . C <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,681,27429,0,0,1018,59282,0,0,322,6590,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,190:10:0:0:10,0,0,0:10,0 0,9,119:3:0:0:2,1,0,0:3,0 0,15,135:5:0:0:5,0,0,0:5,0 17 109 . T C,<*> 0 . DP=19;DPR=17,1,0;I16=16,1,1,0,716,30648,2,4,989,58441,29,841,309,6415,12,144;QS=2.98922,0.0107817,0;SGB=-0.556633;RPBZ=-0.674966;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.6661;SCBZ=3;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,20,191,27,194,191:10:1:0:9,0,1,0:9,1,0 0,9,120,9,120,120:3:0:0:2,1,0,0:3,0,0 0,15,150,15,150,150:5:0:0:5,0,0,0:5,0,0 17 110 . G <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,688,28036,0,0,1018,59282,0,0,320,6550,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,194:10:0:0:10,0,0,0:10,0 0,9,113:3:0:0:2,1,0,0:3,0 0,15,136:5:0:0:5,0,0,0:5,0 17 111 . G <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,573,21453,0,0,1018,59282,0,0,318,6514,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,167:10:0:0:10,0,0,0:10,0 0,9,95:3:0:0:2,1,0,0:3,0 0,15,119:5:0:0:5,0,0,0:5,0 17 112 . C G,<*> 0 . DP=19;DPR=17,1,0;I16=16,1,1,0,657,26565,2,4,989,58441,29,841,301,6277,15,225;QS=2.98907,0.010929,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65292;SCBZ=3;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,20,187,27,190,187:10:1:0:9,0,1,0:9,1,0 0,9,103,9,103,103:3:0:0:2,1,0,0:3,0,0 0,15,135,15,135,135:5:0:0:5,0,0,0:5,0,0 17 113 . A G,<*> 0 . DP=19;DPR=17,1,0;I16=16,1,1,0,635,25055,4,16,989,58441,29,841,297,6207,16,256;QS=2.98817,0.0118343,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65205;SCBZ=3;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,20,172,27,175,172:10:1:0:9,0,1,0:9,1,0 0,9,102,9,102,102:3:0:0:2,1,0,0:3,0,0 0,15,139,15,139,139:5:0:0:5,0,0,0:5,0,0 17 114 . C <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,660,25876,0,0,1018,59282,0,0,310,6446,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,181:10:0:0:10,0,0,0:10,0 0,9,113:3:0:0:2,1,0,0:3,0 0,15,133:5:0:0:5,0,0,0:5,0 17 115 . C A,<*> 0 . DP=21;DPR=19,1,0;I16=17,2,1,0,688,27426,12,144,1078,62882,29,841,283,5827,25,625;QS=2.88785,0.11215,0;SGB=-0.556633;RPBZ=0.260329;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.47798;SCBZ=-0.418446;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,189,30,189,189:10:0:0:10,0,0,0:10,0,0 3,0,86,9,89,93:3:1:0:1,1,1,0:2,1,0 0,21,153,21,153,153:7:0:0:6,1,0,0:7,0,0 17 116 . A C,<*> 0 . DP=21;DPR=19,1,0;I16=17,2,1,0,705,27791,2,4,1078,62882,29,841,287,6073,19,361;QS=2.98873,0.0112676,0;SGB=-0.556633;RPBZ=0.0867763;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.65814;SCBZ=2.65016;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,20,179,27,182,179:10:1:0:9,0,1,0:9,1,0 0,9,102,9,102,102:3:0:0:2,1,0,0:3,0,0 0,21,175,21,175,175:7:0:0:6,1,0,0:7,0,0 17 117 . G <*> 0 . DP=21;DPR=20,0;I16=18,2,0,0,715,28045,0,0,1107,63723,0,0,304,6444,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,185:10:0:0:10,0,0,0:10,0 0,9,97:3:0:0:2,1,0,0:3,0 0,21,177:7:0:0:6,1,0,0:7,0 17 118 . G <*> 0 . DP=20;DPR=19,0;I16=17,2,0,0,620,23470,0,0,1047,60123,0,0,303,6481,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,175:9:0:0:9,0,0,0:9,0 0,9,65:3:0:0:2,1,0,0:3,0 0,21,162:7:0:0:6,1,0,0:7,0 17 119 . G <*> 0 . DP=19;DPR=18,0;I16=16,2,0,0,619,23459,0,0,987,56523,0,0,301,6493,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,176:9:0:0:9,0,0,0:9,0 0,6,76:2:0:0:1,1,0,0:2,0 0,21,160:7:0:0:6,1,0,0:7,0 17 120 . A G,<*> 0 . DP=19;DPR=17,1,0;I16=15,2,1,0,646,25392,4,16,958,55682,29,841,277,5999,23,529;QS=2.9873,0.0126984,0;SGB=-0.556633;RPBZ=0.28942;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.6486;SCBZ=3;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,171,24,174,171:9:1:0:8,0,1,0:8,1,0 0,6,88,6,88,88:2:0:0:1,1,0,0:2,0,0 0,21,171,21,171,171:7:0:0:6,1,0,0:7,0,0 17 121 . G <*> 0 . DP=19;DPR=18,0;I16=16,2,0,0,650,25148,0,0,987,56523,0,0,298,6534,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,181:9:0:0:9,0,0,0:9,0 0,6,84:2:0:0:1,1,0,0:2,0 0,21,168:7:0:0:6,1,0,0:7,0 17 122 . C <*> 0 . DP=20;DPR=19,0;I16=17,2,0,0,696,27784,0,0,1047,60123,0,0,296,6560,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,180:9:0:0:9,0,0,0:9,0 0,9,107:3:0:0:2,1,0,0:3,0 0,21,178:7:0:0:6,1,0,0:7,0 17 123 . T <*> 0 . DP=18;DPR=17,0;I16=15,2,0,0,647,26145,0,0,927,52923,0,0,296,6554,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,170:8:0:0:8,0,0,0:8,0 0,9,123:3:0:0:2,1,0,0:3,0 0,18,166:6:0:0:5,1,0,0:6,0 17 124 . T <*> 0 . DP=19;DPR=18,0;I16=16,2,0,0,606,22002,0,0,987,56523,0,0,296,6564,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,154:9:0:0:9,0,0,0:9,0 0,9,114:3:0:0:2,1,0,0:3,0 0,18,154:6:0:0:5,1,0,0:6,0 17 125 . A T,<*> 0 . DP=18;DPR=16,1,0;I16=14,2,1,0,589,22565,4,16,898,52082,29,841,272,5916,25,625;QS=2.98444,0.0155642,0;SGB=-0.556633;RPBZ=1.02125;MQBZ=-2.16025;MQSBZ=-1.23956;BQBZ=-1.64106;SCBZ=2.91548;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,149,21,152,149:8:1:0:7,0,1,0:7,1,0 0,9,114,9,114,114:3:0:0:2,1,0,0:3,0,0 0,18,162,18,162,162:6:0:0:5,1,0,0:6,0,0 17 126 . A <*> 0 . DP=18;DPR=17,0;I16=15,2,0,0,629,24725,0,0,927,52923,0,0,298,6536,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,162:8:0:0:8,0,0,0:8,0 0,9,117:3:0:0:2,1,0,0:3,0 0,18,174:6:0:0:5,1,0,0:6,0 17 127 . C <*> 0 . DP=18;DPR=17,0;I16=15,2,0,0,627,24331,0,0,927,52923,0,0,299,6549,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,163:8:0:0:8,0,0,0:8,0 0,9,119:3:0:0:2,1,0,0:3,0 0,18,160:6:0:0:5,1,0,0:6,0 17 128 . A <*> 0 . DP=18;DPR=17,0;I16=15,2,0,0,660,26364,0,0,927,52923,0,0,300,6580,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,169:8:0:0:8,0,0,0:8,0 0,9,121:3:0:0:2,1,0,0:3,0 0,18,168:6:0:0:5,1,0,0:6,0 17 129 . A <*> 0 . DP=17;DPR=16,0;I16=14,2,0,0,627,25407,0,0,867,49323,0,0,302,6628,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,168:8:0:0:8,0,0,0:8,0 0,9,124:3:0:0:2,1,0,0:3,0 0,15,159:5:0:0:4,1,0,0:5,0 17 130 . A <*> 0 . DP=17;DPR=16,0;I16=14,2,0,0,627,25419,0,0,867,49323,0,0,304,6692,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,169:8:0:0:8,0,0,0:8,0 0,9,124:3:0:0:2,1,0,0:3,0 0,15,152:5:0:0:4,1,0,0:5,0 17 131 . C <*> 0 . DP=16;DPR=15,0;I16=13,2,0,0,593,24003,0,0,838,48482,0,0,280,6096,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,167:7:0:0:7,0,0,0:7,0 0,9,120:3:0:0:2,1,0,0:3,0 0,15,147:5:0:0:4,1,0,0:5,0 17 132 . A <*> 0 . DP=16;DPR=15,0;I16=13,2,0,0,610,25250,0,0,838,48482,0,0,281,6139,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,169:7:0:0:7,0,0,0:7,0 0,9,120:3:0:0:2,1,0,0:3,0 0,15,151:5:0:0:4,1,0,0:5,0 17 133 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,163:7:0:0:7,0,0,0:7,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,150:5:0:0:4,1,0,0:5,0 17 134 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,177:7:0:0:7,0,0,0:7,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,152:5:0:0:4,1,0,0:5,0 17 135 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,605,24553,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:7,0,0,0:7,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,159:5:0:0:4,1,0,0:5,0 17 136 . G <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:7,0,0,0:7,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,134:5:0:0:4,1,0,0:5,0 17 137 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,160:7:0:0:7,0,0,0:7,0 0,9,104:3:0:0:2,1,0,0:3,0 0,15,139:5:0:0:4,1,0,0:5,0 17 138 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:7,0,0,0:7,0 0,9,108:3:0:0:2,1,0,0:3,0 0,15,142:5:0:0:4,1,0,0:5,0 17 139 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,161:7:0:0:7,0,0,0:7,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,143:5:0:0:4,1,0,0:5,0 17 140 . A <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,163:7:0:0:7,0,0,0:7,0 0,9,107:3:0:0:2,1,0,0:3,0 0,15,153:5:0:0:4,1,0,0:5,0 17 141 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,158:6:0:0:6,0,0,0:6,0 0,9,108:3:0:0:2,1,0,0:3,0 0,15,142:5:0:0:4,1,0,0:5,0 17 142 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,157:6:0:0:6,0,0,0:6,0 0,9,97:3:0:0:2,1,0,0:3,0 0,15,129:5:0:0:4,1,0,0:5,0 17 143 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,426,13778,0,0,778,44882,0,0,292,6648,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,128:6:0:0:6,0,0,0:6,0 0,9,95:3:0:0:2,1,0,0:3,0 0,15,102:5:0:0:4,1,0,0:5,0 17 144 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,152:6:0:0:6,0,0,0:6,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,129:5:0:0:4,1,0,0:5,0 17 145 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,153:6:0:0:6,0,0,0:6,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,138:5:0:0:4,1,0,0:5,0 17 146 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,152:6:0:0:6,0,0,0:6,0 0,9,103:3:0:0:2,1,0,0:3,0 0,15,128:5:0:0:4,1,0,0:5,0 17 147 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,150:6:0:0:6,0,0,0:6,0 0,9,99:3:0:0:2,1,0,0:3,0 0,15,140:5:0:0:4,1,0,0:5,0 17 148 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,157:6:0:0:6,0,0,0:6,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,146:5:0:0:4,1,0,0:5,0 17 149 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,148:6:0:0:6,0,0,0:6,0 0,9,109:3:0:0:2,1,0,0:3,0 0,15,140:5:0:0:4,1,0,0:5,0 17 150 . T <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,153:6:0:0:6,0,0,0:6,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,152:5:0:0:4,1,0,0:5,0 17 151 . G <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,157:6:0:0:6,0,0,0:6,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,144:5:0:0:4,1,0,0:5,0 17 152 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,168:7:0:0:7,0,0,0:7,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,146:5:0:0:4,1,0,0:5,0 17 153 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,156:7:0:0:7,0,0,0:7,0 0,6,81:2:0:0:1,1,0,0:2,0 0,15,153:5:0:0:4,1,0,0:5,0 17 154 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,159:7:0:0:7,0,0,0:7,0 0,6,83:2:0:0:1,1,0,0:2,0 0,15,139:5:0:0:4,1,0,0:5,0 17 155 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:7,0,0,0:7,0 0,6,85:2:0:0:1,1,0,0:2,0 0,15,139:5:0:0:4,1,0,0:5,0 17 156 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,163:7:0:0:7,0,0,0:7,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,150:5:0:0:4,1,0,0:5,0 17 157 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,169:7:0:0:7,0,0,0:7,0 0,6,85:2:0:0:1,1,0,0:2,0 0,15,149:5:0:0:4,1,0,0:5,0 17 158 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,170:7:0:0:7,0,0,0:7,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,159:5:0:0:4,1,0,0:5,0 17 159 . A G,<*> 0 . DP=15;DPR=14,1,0;I16=12,2,1,0,519,19467,5,25,809,47641,60,3600,260,5880,0,0;QS=2.97076,0.0292398,0;SGB=-0.556633;RPBZ=-1.62019;MQBZ=0.267261;MQSBZ=-2.54951;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,157,21,157,157:7:0:0:7,0,0,0:7,0,0 0,6,83,6,83,83:2:0:0:1,1,0,0:2,0,0 0,10,129,15,132,129:6:1:0:4,1,1,0:5,1,0 17 160 . G <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,165:7:0:0:7,0,0,0:7,0 0,6,85:2:0:0:1,1,0,0:2,0 0,18,139:6:0:0:5,1,0,0:6,0 17 161 . A <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,157:7:0:0:7,0,0,0:7,0 0,6,83:2:0:0:1,1,0,0:2,0 0,18,162:6:0:0:5,1,0,0:6,0 17 162 . A <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,558,21206,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,147:7:0:0:7,0,0,0:7,0 0,6,87:2:0:0:1,1,0,0:2,0 0,18,167:6:0:0:5,1,0,0:6,0 17 163 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,505,18789,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,154:7:0:0:7,0,0,0:7,0 0,6,79:2:0:0:1,1,0,0:2,0 0,15,138:5:0:0:4,1,0,0:5,0 17 164 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,131:6:0:0:6,0,0,0:6,0 0,6,79:2:0:0:1,1,0,0:2,0 0,18,136:6:0:0:5,1,0,0:6,0 17 165 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,473,17609,0,0,809,47641,0,0,252,5720,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,149:6:0:0:6,0,0,0:6,0 0,6,80:2:0:0:1,1,0,0:2,0 0,18,127:6:0:0:5,1,0,0:6,0 17 166 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,502,19174,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,145:6:0:0:6,0,0,0:6,0 0,6,82:2:0:0:1,1,0,0:2,0 0,18,149:6:0:0:5,1,0,0:6,0 17 167 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,486,17932,0,0,809,47641,0,0,252,5696,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,132:6:0:0:6,0,0,0:6,0 0,6,86:2:0:0:1,1,0,0:2,0 0,18,148:6:0:0:5,1,0,0:6,0 17 168 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,145:6:0:0:6,0,0,0:6,0 0,6,82:2:0:0:1,1,0,0:2,0 0,18,140:6:0:0:5,1,0,0:6,0 17 169 . C <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,408,14260,0,0,749,44041,0,0,252,5670,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,106:5:0:0:5,0,0,0:5,0 0,6,76:2:0:0:1,1,0,0:2,0 0,18,145:6:0:0:5,1,0,0:6,0 17 170 . C <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,128:5:0:0:5,0,0,0:5,0 0,6,80:2:0:0:1,1,0,0:2,0 0,18,143:6:0:0:5,1,0,0:6,0 17 171 . A <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,134:5:0:0:5,0,0,0:5,0 0,6,81:2:0:0:1,1,0,0:2,0 0,18,166:6:0:0:5,1,0,0:6,0 17 172 . C <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,451,16539,0,0,749,44041,0,0,249,5505,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,138:5:0:0:5,0,0,0:5,0 0,6,75:2:0:0:1,1,0,0:2,0 0,18,133:6:0:0:5,1,0,0:6,0 17 173 . C <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,437,15357,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,121:5:0:0:5,0,0,0:5,0 0,6,78:2:0:0:1,1,0,0:2,0 0,18,146:6:0:0:5,1,0,0:6,0 17 174 . G <*> 0 . DP=13;DPR=13,0;I16=12,1,0,0,356,10710,0,0,749,44041,0,0,248,5464,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,111:5:0:0:5,0,0,0:5,0 0,3,27:1:0:0:1,0,0,0:1,0 0,21,116:7:0:0:6,1,0,0:7,0 17 175 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,515,19433,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,145:6:0:0:6,0,0,0:6,0 0,3,41:1:0:0:1,0,0,0:1,0 0,21,175:7:0:0:6,1,0,0:7,0 17 176 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,146:6:0:0:6,0,0,0:6,0 0,3,44:1:0:0:1,0,0,0:1,0 0,21,152:7:0:0:6,1,0,0:7,0 17 177 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,490,17476,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,139:6:0:0:6,0,0,0:6,0 0,3,44:1:0:0:1,0,0,0:1,0 0,21,158:7:0:0:6,1,0,0:7,0 17 178 . A <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,147:6:0:0:6,0,0,0:6,0 0,3,42:1:0:0:1,0,0,0:1,0 0,21,172:7:0:0:6,1,0,0:7,0 17 179 . A <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,134:6:0:0:6,0,0,0:6,0 0,3,44:1:0:0:1,0,0,0:1,0 0,21,170:7:0:0:6,1,0,0:7,0 17 180 . A <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,432,14702,0,0,809,47641,0,0,256,5534,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,126:6:0:0:6,0,0,0:6,0 0,3,43:1:0:0:1,0,0,0:1,0 0,21,148:7:0:0:6,1,0,0:7,0 17 181 . G <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,469,17345,0,0,809,47641,0,0,257,5571,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,156:6:0:0:6,0,0,0:6,0 0,3,41:1:0:0:1,0,0,0:1,0 0,21,142:7:0:0:6,1,0,0:7,0 17 182 . A <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,150:7:0:0:7,0,0,0:7,0 0,3,43:1:0:0:1,0,0,0:1,0 0,21,159:7:0:0:6,1,0,0:7,0 17 183 . C <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,491,17483,0,0,869,51241,0,0,260,5688,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,159:7:0:0:7,0,0,0:7,0 0,3,40:1:0:0:1,0,0,0:1,0 0,21,140:7:0:0:6,1,0,0:7,0 17 184 . A <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,158:7:0:0:7,0,0,0:7,0 0,3,41:1:0:0:1,0,0,0:1,0 0,21,163:7:0:0:6,1,0,0:7,0 17 185 . C <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,499,17439,0,0,869,51241,0,0,263,5817,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,150:7:0:0:7,0,0,0:7,0 0,3,38:1:0:0:1,0,0,0:1,0 0,21,161:7:0:0:6,1,0,0:7,0 17 186 . G <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,393,11519,0,0,869,51241,0,0,264,5878,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,118:7:0:0:7,0,0,0:7,0 0,3,32:1:0:0:1,0,0,0:1,0 0,21,123:7:0:0:6,1,0,0:7,0 17 187 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,147:6:0:0:6,0,0,0:6,0 0,3,38:1:0:0:1,0,0,0:1,0 0,21,172:7:0:0:6,1,0,0:7,0 17 188 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,147:6:0:0:6,0,0,0:6,0 0,3,37:1:0:0:1,0,0,0:1,0 0,21,162:7:0:0:6,1,0,0:7,0 17 189 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,152:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,21,167:7:0:0:6,1,0,0:7,0 17 190 . A C,<*> 0 . DP=15;DPR=14,1,0;I16=12,2,1,0,500,18230,5,25,778,44882,60,3600,243,5381,25,625;QS=2.97664,0.0233645,0;SGB=-0.556633;RPBZ=0;MQBZ=0.392232;MQSBZ=-3.74166;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,138,18,138,138:6:0:0:6,0,0,0:6,0,0 0,6,68,6,68,68:2:0:0:1,1,0,0:2,0,0 0,12,153,18,156,153:7:1:0:5,1,1,0:6,1,0 17 191 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,143:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,21,169:7:0:0:6,1,0,0:7,0 17 192 . G <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,143:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,21,151:7:0:0:6,1,0,0:7,0 17 193 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,140:6:0:0:6,0,0,0:6,0 0,6,63:2:0:0:1,1,0,0:2,0 0,21,157:7:0:0:6,1,0,0:7,0 17 194 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,471,16817,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,144:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,18,145:6:0:0:5,1,0,0:6,0 17 195 . C <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,159:6:0:0:5,1,0,0:6,0 0,6,71:2:0:0:1,1,0,0:2,0 0,18,160:6:0:0:5,1,0,0:6,0 17 196 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,166:6:0:0:5,1,0,0:6,0 0,6,69:2:0:0:1,1,0,0:2,0 0,18,138:6:0:0:5,1,0,0:6,0 17 197 . G <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,164:6:0:0:5,1,0,0:6,0 0,6,68:2:0:0:1,1,0,0:2,0 0,18,134:6:0:0:5,1,0,0:6,0 17 198 . C <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,172:6:0:0:5,1,0,0:6,0 0,6,70:2:0:0:1,1,0,0:2,0 0,18,164:6:0:0:5,1,0,0:6,0 17 199 . T <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,162:6:0:0:5,1,0,0:6,0 0,6,73:2:0:0:1,1,0,0:2,0 0,18,154:6:0:0:5,1,0,0:6,0 17 200 . T <*> 0 . DP=15;DPR=15,0;I16=11,4,0,0,545,19991,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,161:6:0:0:5,1,0,0:6,0 0,9,89:3:0:0:1,2,0,0:3,0 0,18,154:6:0:0:5,1,0,0:6,0 17 201 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,171:7:0:0:6,1,0,0:7,0 0,9,89:3:0:0:1,2,0,0:3,0 0,18,157:6:0:0:5,1,0,0:6,0 17 202 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,178:7:0:0:6,1,0,0:7,0 0,9,84:3:0:0:1,2,0,0:3,0 0,18,163:6:0:0:5,1,0,0:6,0 17 203 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,166:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,18,153:6:0:0:5,1,0,0:6,0 17 204 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,91:3:0:0:1,2,0,0:3,0 0,18,163:6:0:0:5,1,0,0:6,0 17 205 . T <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,188:7:0:0:6,1,0,0:7,0 0,9,95:3:0:0:1,2,0,0:3,0 0,18,173:6:0:0:5,1,0,0:6,0 17 206 . G <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,180:7:0:0:6,1,0,0:7,0 0,9,89:3:0:0:1,2,0,0:3,0 0,18,143:6:0:0:5,1,0,0:6,0 17 207 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,179:7:0:0:6,1,0,0:7,0 0,9,93:3:0:0:1,2,0,0:3,0 0,18,151:6:0:0:5,1,0,0:6,0 17 208 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,184:7:0:0:6,1,0,0:7,0 0,9,93:3:0:0:1,2,0,0:3,0 0,18,154:6:0:0:5,1,0,0:6,0 17 209 . T <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,91:3:0:0:1,2,0,0:3,0 0,18,146:6:0:0:5,1,0,0:6,0 17 210 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,151:6:0:0:5,1,0,0:6,0 17 211 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,153:6:0:0:5,1,0,0:6,0 17 212 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,181:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,152:6:0:0:5,1,0,0:6,0 17 213 . T <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,181:7:0:0:6,1,0,0:7,0 0,9,95:3:0:0:1,2,0,0:3,0 0,18,165:6:0:0:5,1,0,0:6,0 17 214 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,539,19501,0,0,836,46564,0,0,262,5732,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,176:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,120:6:0:0:5,1,0,0:6,0 17 215 . G <*> 0 . DP=15;DPR=15,0;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,15,105:5:0:0:5,0,0,0:5,0 17 216 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,473,16981,0,0,747,42123,0,0,263,5791,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,12,85:4:0:0:4,0,0,0:4,0 17 217 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,181:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,12,97:4:0:0:4,0,0,0:4,0 17 218 . G <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,178:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,12,110:4:0:0:4,0,0,0:4,0 17 219 . T <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,88:3:0:0:1,2,0,0:3,0 0,12,89:4:0:0:4,0,0,0:4,0 17 220 . G <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,495,18407,0,0,747,42123,0,0,267,6079,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,188:7:0:0:6,1,0,0:7,0 0,9,88:3:0:0:1,2,0,0:3,0 0,12,84:4:0:0:4,0,0,0:4,0 17 221 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,488,17688,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,176:7:0:0:6,1,0,0:7,0 0,9,89:3:0:0:1,2,0,0:3,0 0,12,101:4:0:0:4,0,0,0:4,0 17 222 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,479,17747,0,0,747,42123,0,0,267,6203,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,186:7:0:0:6,1,0,0:7,0 0,9,89:3:0:0:1,2,0,0:3,0 0,12,73:4:0:0:4,0,0,0:4,0 17 223 . G T,<*> 0 . DP=13;DPR=12,1,0;I16=9,3,1,0,412,14782,8,64,627,34923,60,3600,243,5657,25,625;QS=2.96596,0.0340426,0;SGB=-0.556633;RPBZ=1.07052;MQBZ=0.547723;MQSBZ=-3.4641;BQBZ=-1.60577;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,11,166,18,169,167:7:1:0:5,1,1,0:6,1,0 0,6,53,6,53,53:2:0:0:0,2,0,0:2,0,0 0,12,81,12,81,81:4:0:0:4,0,0,0:4,0,0 17 224 . G <*> 0 . DP=12;DPR=12,0;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,168:6:0:0:5,1,0,0:6,0 0,6,50:2:0:0:0,2,0,0:2,0 0,12,70:4:0:0:4,0,0,0:4,0 17 225 . C <*> 0 . DP=12;DPR=12,0;I16=9,3,0,0,390,13960,0,0,627,34923,0,0,272,6466,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,165:6:0:0:5,1,0,0:6,0 0,6,48:2:0:0:0,2,0,0:2,0 0,12,86:4:0:0:4,0,0,0:4,0 17 226 . A G,C,<*> 0 . DP=13;DPR=11,1,1,0;I16=8,3,1,1,381,13669,6,18,567,31323,89,4441,248,5894,44,986;QS=2.94293,0.0392157,0.0178571,0;VDB=0.84;SGB=-2.62246;RPBZ=-0.592157;MQBZ=-0.615457;MQSBZ=-3.4641;BQBZ=-2.17723;SCBZ=2.34521;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,159,12,162,159,18,159,162,159:7:1:0:5,1,0,1:6,0,1,0 0,6,53,6,53,53,6,53,53,53:2:0:0:0,2,0,0:2,0,0,0 0,5,79,9,82,80,9,82,80,80:4:1:0:3,0,1,0:3,1,0,0 17 227 . C <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,412,14342,0,0,656,35764,0,0,292,6878,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,190:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,75:4:0:0:4,0,0,0:4,0 17 228 . C <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,187:7:0:0:5,2,0,0:7,0 0,6,45:2:0:0:0,2,0,0:2,0 0,12,96:4:0:0:4,0,0,0:4,0 17 229 . G <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,368,11524,0,0,656,35764,0,0,292,6898,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,145:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,70:4:0:0:4,0,0,0:4,0 17 230 . C <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,460,16788,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,186:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,99:4:0:0:4,0,0,0:4,0 17 231 . C <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,428,15932,0,0,656,35764,0,0,292,6950,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,83:4:0:0:4,0,0,0:4,0 17 232 . C <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,474,17240,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,197:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,101:5:0:0:5,0,0,0:5,0 17 233 . A <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,192:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,119:5:0:0:5,0,0,0:5,0 17 234 . A <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,123:5:0:0:5,0,0,0:5,0 17 235 . A <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,488,17796,0,0,716,39364,0,0,291,6951,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,186:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,115:5:0:0:5,0,0,0:5,0 17 236 . G <*> 0 . DP=15;DPR=15,0;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,206:8:0:0:6,2,0,0:8,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,103:5:0:0:5,0,0,0:5,0 17 237 . A C,<*> 0 . DP=14;DPR=13,1,0;I16=9,4,1,0,465,16877,8,64,656,35764,60,3600,266,6282,25,625;QS=2.93162,0.0683761,0;SGB=-0.556633;RPBZ=1.11754;MQBZ=0.632456;MQSBZ=-3.60555;BQBZ=-1.61959;SCBZ=-0.27735;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,206,24,206,206:8:0:0:6,2,0,0:8,0,0 0,6,53,6,53,53:2:0:0:0,2,0,0:2,0,0 0,3,84,9,87,87:4:1:0:3,0,1,0:3,1,0 17 238 . C <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,211:8:0:0:6,2,0,0:8,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,82:4:0:0:4,0,0,0:4,0 17 239 . A <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,223:9:0:0:6,3,0,0:9,0 0,6,50:2:0:0:0,2,0,0:2,0 0,12,108:4:0:0:4,0,0,0:4,0 17 240 . C <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,220:9:0:0:6,3,0,0:9,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,106:4:0:0:4,0,0,0:4,0 17 241 . G <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,456,14780,0,0,776,42964,0,0,292,6688,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,203:9:0:0:6,3,0,0:9,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,64:4:0:0:4,0,0,0:4,0 17 242 . C <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,242:9:0:0:6,3,0,0:9,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,94:4:0:0:4,0,0,0:4,0 17 243 . C <*> 0 . DP=16;DPR=16,0;I16=10,6,0,0,531,19777,0,0,805,43805,0,0,297,6597,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,219:9:0:0:6,3,0,0:9,0 0,9,54:3:0:0:0,3,0,0:3,0 0,12,104:4:0:0:4,0,0,0:4,0 17 244 . C <*> 0 . DP=16;DPR=16,0;I16=10,6,0,0,611,23627,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,244:9:0:0:6,3,0,0:9,0 0,9,72:3:0:0:0,3,0,0:3,0 0,12,106:4:0:0:4,0,0,0:4,0 17 245 . A <*> 0 . DP=17;DPR=17,0;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,236:9:0:0:6,3,0,0:9,0 0,12,93:4:0:0:0,4,0,0:4,0 0,12,115:4:0:0:4,0,0,0:4,0 17 246 . T <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,247:10:0:0:6,4,0,0:10,0 0,12,94:4:0:0:0,4,0,0:4,0 0,12,98:4:0:0:4,0,0,0:4,0 17 247 . G <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:6,4,0,0:10,0 0,12,83:4:0:0:0,4,0,0:4,0 0,12,103:4:0:0:4,0,0,0:4,0 17 248 . T <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,234:10:0:0:6,4,0,0:10,0 0,12,86:4:0:0:0,4,0,0:4,0 0,12,114:4:0:0:4,0,0,0:4,0 17 249 . C <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,253:10:0:0:6,4,0,0:10,0 0,12,79:4:0:0:0,4,0,0:4,0 0,12,112:4:0:0:4,0,0,0:4,0 17 250 . C <*> 0 . DP=19;DPR=19,0;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,248:10:0:0:6,4,0,0:10,0 0,12,89:4:0:0:0,4,0,0:4,0 0,15,142:5:0:0:4,1,0,0:5,0 17 251 . A <*> 0 . DP=19;DPR=19,0;I16=10,9,0,0,697,26587,0,0,923,49087,0,0,313,6627,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,234:10:0:0:6,4,0,0:10,0 0,12,97:4:0:0:0,4,0,0:4,0 0,15,148:5:0:0:4,1,0,0:5,0 17 252 . G <*> 0 . DP=18;DPR=18,0;I16=9,9,0,0,652,24752,0,0,863,45487,0,0,316,6646,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,243:9:0:0:5,4,0,0:9,0 0,12,91:4:0:0:0,4,0,0:4,0 0,15,126:5:0:0:4,1,0,0:5,0 17 253 . C <*> 0 . DP=19;DPR=19,0;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,247:9:0:0:5,4,0,0:9,0 0,12,86:4:0:0:0,4,0,0:4,0 0,18,155:6:0:0:4,2,0,0:6,0 17 254 . T <*> 0 . DP=20;DPR=20,0;I16=10,10,0,0,731,27661,0,0,952,49928,0,0,323,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,254:10:0:0:6,4,0,0:10,0 0,12,78:4:0:0:0,4,0,0:4,0 0,18,164:6:0:0:4,2,0,0:6,0 17 255 . T <*> 0 . DP=21;DPR=21,0;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,241:11:0:0:7,4,0,0:11,0 0,12,95:4:0:0:0,4,0,0:4,0 0,18,161:6:0:0:4,2,0,0:6,0 17 256 . A <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,110:5:0:0:0,5,0,0:5,0 0,18,166:6:0:0:4,2,0,0:6,0 17 257 . T <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,247:11:0:0:7,4,0,0:11,0 0,15,113:5:0:0:0,5,0,0:5,0 0,18,168:6:0:0:4,2,0,0:6,0 17 258 . T <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:7,4,0,0:11,0 0,15,116:5:0:0:0,5,0,0:5,0 0,18,155:6:0:0:4,2,0,0:6,0 17 259 . C <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,793,29873,0,0,1049,54897,0,0,353,7377,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,92:5:0:0:0,5,0,0:5,0 0,18,170:6:0:0:4,2,0,0:6,0 17 260 . T <*> 0 . DP=21;DPR=21,0;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,118:5:0:0:0,5,0,0:5,0 0,15,156:5:0:0:3,2,0,0:5,0 17 261 . G <*> 0 . DP=21;DPR=21,0;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:7,4,0,0:11,0 0,15,111:5:0:0:0,5,0,0:5,0 0,15,122:5:0:0:3,2,0,0:5,0 17 262 . C <*> 0 . DP=22;DPR=22,0;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,99:5:0:0:0,5,0,0:5,0 0,18,164:6:0:0:3,3,0,0:6,0 17 263 . C <*> 0 . DP=22;DPR=22,0;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,98:5:0:0:0,5,0,0:5,0 0,18,168:6:0:0:3,3,0,0:6,0 17 264 . C <*> 0 . DP=22;DPR=22,0;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,104:5:0:0:0,5,0,0:5,0 0,18,172:6:0:0:3,3,0,0:6,0 17 265 . A <*> 0 . DP=21;DPR=21,0;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,114:5:0:0:0,5,0,0:5,0 0,15,129:5:0:0:2,3,0,0:5,0 17 266 . G <*> 0 . DP=21;DPR=21,0;I16=9,12,0,0,754,28204,0,0,989,51297,0,0,394,8458,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,99:5:0:0:0,5,0,0:5,0 0,15,138:5:0:0:2,3,0,0:5,0 17 267 . T G,<*> 0 . DP=21;DPR=20,1,0;I16=9,11,0,1,739,27465,8,64,960,50456,29,841,373,7935,25,625;QS=2.94203,0.057971,0;SGB=-0.556633;RPBZ=-0.330396;MQBZ=-1.23153;MQSBZ=-3.3021;BQBZ=-1.66282;SCBZ=2.91633;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254,33,254,254:11:0:0:7,4,0,0:11,0,0 0,6,93,12,96,96:5:1:0:0,4,0,1:4,1,0 0,15,149,15,149,149:5:0:0:2,3,0,0:5,0,0 17 268 . T <*> 0 . DP=21;DPR=21,0;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,238:11:0:0:7,4,0,0:11,0 0,15,110:5:0:0:0,5,0,0:5,0 0,15,156:5:0:0:2,3,0,0:5,0 17 269 . C <*> 0 . DP=22;DPR=22,0;I16=9,13,0,0,767,28641,0,0,1018,52138,0,0,406,8836,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,91:5:0:0:0,5,0,0:5,0 0,15,154:5:0:0:2,3,0,0:5,0 17 270 . C <*> 0 . DP=22;DPR=22,0;I16=9,13,0,0,766,28210,0,0,1018,52138,0,0,410,8962,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,98:5:0:0:0,5,0,0:5,0 0,15,143:5:0:0:2,3,0,0:5,0 17 271 . T <*> 0 . DP=22;DPR=22,0;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,113:5:0:0:0,5,0,0:5,0 0,15,152:5:0:0:2,3,0,0:5,0 17 272 . C <*> 0 . DP=22;DPR=22,0;I16=9,13,0,0,815,31449,0,0,1018,52138,0,0,415,9143,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,97:5:0:0:0,5,0,0:5,0 0,15,149:5:0:0:2,3,0,0:5,0 17 273 . T C,<*> 0 . DP=22;DPR=21,1,0;I16=9,12,0,1,798,30664,5,25,989,51297,29,841,392,8620,25,625;QS=2.96094,0.0390625,0;SGB=-0.556633;RPBZ=-0.236567;MQBZ=-1.16701;MQSBZ=-3.42286;BQBZ=-1.66779;SCBZ=3.00076;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255,36,255,255:12:0:0:7,5,0,0:12,0,0 0,7,89,12,92,90:5:1:0:0,4,0,1:4,1,0 0,15,161,15,161,161:5:0:0:2,3,0,0:5,0,0 17 274 . C <*> 0 . DP=22;DPR=22,0;I16=9,13,0,0,767,28193,0,0,1018,52138,0,0,419,9371,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,101:5:0:0:0,5,0,0:5,0 0,15,144:5:0:0:2,3,0,0:5,0 17 275 . C <*> 0 . DP=20;DPR=20,0;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,15,114:5:0:0:0,5,0,0:5,0 0,12,122:4:0:0:1,3,0,0:4,0 17 276 . A <*> 0 . DP=20;DPR=20,0;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,253:11:0:0:6,5,0,0:11,0 0,15,122:5:0:0:0,5,0,0:5,0 0,12,124:4:0:0:1,3,0,0:4,0 17 277 . G <*> 0 . DP=20;DPR=20,0;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,15,114:5:0:0:0,5,0,0:5,0 0,12,121:4:0:0:1,3,0,0:4,0 17 278 . A C,<*> 0 . DP=21;DPR=20,1,0;I16=6,14,1,0,722,26452,7,49,867,42179,60,3600,415,9521,11,121;QS=2.97935,0.020649,0;SGB=-0.556633;RPBZ=1.65198;MQBZ=1.0247;MQSBZ=-3.24037;BQBZ=-1.66667;SCBZ=-0.324037;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,22,231,30,234,231:11:1:0:5,5,1,0:10,1,0 0,18,123,18,123,123:6:0:0:0,6,0,0:6,0,0 0,12,121,12,121,121:4:0:0:1,3,0,0:4,0,0 17 279 . A <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,123:6:0:0:0,6,0,0:6,0 0,12,122:4:0:0:1,3,0,0:4,0 17 280 . A <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,253:12:0:0:6,6,0,0:12,0 0,18,130:6:0:0:0,6,0,0:6,0 0,12,129:4:0:0:1,3,0,0:4,0 17 281 . G <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,122:6:0:0:0,6,0,0:6,0 0,12,123:4:0:0:1,3,0,0:4,0 17 282 . G <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,253:12:0:0:6,6,0,0:12,0 0,18,124:6:0:0:0,6,0,0:6,0 0,12,119:4:0:0:1,3,0,0:4,0 17 283 . C <*> 0 . DP=23;DPR=23,0;I16=7,16,0,0,829,31789,0,0,1016,50220,0,0,431,9599,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,125:6:0:0:0,6,0,0:6,0 0,15,122:5:0:0:1,4,0,0:5,0 17 284 . T <*> 0 . DP=23;DPR=23,0;I16=7,16,0,0,895,35059,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,126:6:0:0:0,6,0,0:6,0 0,15,138:5:0:0:1,4,0,0:5,0 17 285 . G <*> 0 . DP=23;DPR=23,0;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,119:6:0:0:0,6,0,0:6,0 0,15,132:5:0:0:1,4,0,0:5,0 17 286 . C <*> 0 . DP=24;DPR=24,0;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,21,150:7:0:0:1,6,0,0:7,0 0,15,134:5:0:0:1,4,0,0:5,0 17 287 . A <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,178:8:0:0:2,6,0,0:8,0 0,15,133:5:0:0:1,4,0,0:5,0 17 288 . T <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,184:8:0:0:2,6,0,0:8,0 0,15,146:5:0:0:1,4,0,0:5,0 17 289 . G <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,185:8:0:0:2,6,0,0:8,0 0,15,136:5:0:0:1,4,0,0:5,0 17 290 . G <*> 0 . DP=23;DPR=23,0;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,240:11:0:0:5,6,0,0:11,0 0,21,164:7:0:0:2,5,0,0:7,0 0,15,126:5:0:0:1,4,0,0:5,0 17 291 . T <*> 0 . DP=24;DPR=24,0;I16=8,16,0,0,850,31716,0,0,1107,56579,0,0,434,9648,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,244:11:0:0:5,6,0,0:11,0 0,21,168:7:0:0:2,5,0,0:7,0 0,18,138:6:0:0:1,5,0,0:6,0 17 292 . T <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,253:11:0:0:5,6,0,0:11,0 0,24,181:8:0:0:3,5,0,0:8,0 0,18,156:6:0:0:1,5,0,0:6,0 17 293 . G <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,946,35376,0,0,1227,63779,0,0,439,9713,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,196:8:0:0:3,5,0,0:8,0 0,18,148:6:0:0:1,5,0,0:6,0 17 294 . A <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,252:12:0:0:6,6,0,0:12,0 0,24,201:8:0:0:3,5,0,0:8,0 0,18,161:6:0:0:1,5,0,0:6,0 17 295 . C <*> 0 . DP=25;DPR=25,0;I16=10,15,0,0,909,34117,0,0,1198,62938,0,0,447,9833,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,183:8:0:0:3,5,0,0:8,0 0,18,159:6:0:0:1,5,0,0:6,0 17 296 . A <*> 0 . DP=25;DPR=25,0;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,169:8:0:0:3,5,0,0:8,0 0,18,169:6:0:0:1,5,0,0:6,0 17 297 . C G,<*> 0 . DP=25;DPR=24,1,0;I16=9,15,1,0,901,34305,4,16,1138,59338,60,3600,445,9901,10,100;QS=2.98261,0.0173913,0;SGB=-0.556633;RPBZ=-1.24856;MQBZ=0.806872;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.368383;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255,33,255,255:11:0:0:6,5,0,0:11,0,0 0,15,168,21,171,168:8:1:0:2,5,1,0:7,1,0 0,18,161,18,161,161:6:0:0:1,5,0,0:6,0,0 17 298 . A <*> 0 . DP=26;DPR=26,0;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,184:8:0:0:3,5,0,0:8,0 0,21,191:7:0:0:2,5,0,0:7,0 17 299 . C <*> 0 . DP=27;DPR=26,0;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,193:8:0:0:3,5,0,0:8,0 0,21,189:7:0:0:2,5,0,0:7,0 17 300 . A <*> 0 . DP=27;DPR=26,0;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,204:8:0:0:3,5,0,0:8,0 0,21,210:7:0:0:2,5,0,0:7,0 17 301 . G <*> 0 . DP=25;DPR=24,0;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,21,195:7:0:0:3,4,0,0:7,0 0,21,196:7:0:0:2,5,0,0:7,0 17 302 . T <*> 0 . DP=25;DPR=24,0;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,231:10:0:0:5,5,0,0:10,0 0,21,172:7:0:0:3,4,0,0:7,0 0,21,202:7:0:0:2,5,0,0:7,0 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;DPR=6,19;I16=2,4,8,11,240,9600,760,30400,236,10564,993,55133,109,2229,377,8629;QS=0.539485,2.46052;VDB=0.241622;SGB=-4.22417;RPBZ=1.11989;MQBZ=1.47646;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.268121;MQ0F=0 PL:DP:DV:SP:DP4:DPR 161,0,99:11:6:6:1,4,4,2:5,6 158,0,14:7:6:0:1,0,2,4:1,6 201,21,0:7:7:0:0,0,2,5:0,7 17 303 . G <*> 0 . DP=25;DPR=25,0;I16=10,15,0,0,968,37972,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,21,197:7:0:0:3,4,0,0:7,0 0,21,195:7:0:0:2,5,0,0:7,0 17 304 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,206:8:0:0:4,4,0,0:8,0 0,24,200:8:0:0:2,6,0,0:8,0 17 305 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,213:8:0:0:4,4,0,0:8,0 0,24,211:8:0:0:2,6,0,0:8,0 17 306 . T <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,207:8:0:0:4,4,0,0:8,0 0,24,217:8:0:0:2,6,0,0:8,0 17 307 . G <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,989,37911,0,0,1318,70138,0,0,523,11823,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,189:8:0:0:4,4,0,0:8,0 0,24,203:8:0:0:2,6,0,0:8,0 17 308 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,178:8:0:0:4,4,0,0:8,0 0,24,185:8:0:0:2,6,0,0:8,0 17 309 . G <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,243:11:0:0:5,6,0,0:11,0 0,24,183:8:0:0:4,4,0,0:8,0 0,24,205:8:0:0:2,6,0,0:8,0 17 310 . A <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,200:8:0:0:4,4,0,0:8,0 0,24,217:8:0:0:2,6,0,0:8,0 17 311 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,215:8:0:0:4,4,0,0:8,0 0,24,210:8:0:0:2,6,0,0:8,0 17 312 . A <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,237:10:0:0:4,6,0,0:10,0 0,24,215:8:0:0:4,4,0,0:8,0 0,24,218:8:0:0:2,6,0,0:8,0 17 313 . A <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,235:10:0:0:4,6,0,0:10,0 0,24,219:8:0:0:4,4,0,0:8,0 0,24,215:8:0:0:2,6,0,0:8,0 17 314 . A <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,250:11:0:0:4,7,0,0:11,0 0,24,217:8:0:0:4,4,0,0:8,0 0,24,227:8:0:0:2,6,0,0:8,0 17 315 . G <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,1023,40789,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:4,6,0,0:10,0 0,24,216:8:0:0:4,4,0,0:8,0 0,24,225:8:0:0:2,6,0,0:8,0 17 316 . C <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,992,39446,0,0,1349,72897,0,0,564,12918,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,27,184:9:0:0:4,5,0,0:9,0 0,24,224:8:0:0:2,6,0,0:8,0 17 317 . T <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1025,40437,0,0,1349,72897,0,0,567,12957,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,27,229:9:0:0:4,5,0,0:9,0 0,24,206:8:0:0:2,6,0,0:8,0 17 318 . G <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,249:10:0:0:4,6,0,0:10,0 0,27,235:9:0:0:4,5,0,0:9,0 0,24,208:8:0:0:2,6,0,0:8,0 17 319 . A <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1005,38775,0,0,1349,72897,0,0,572,13050,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,249:10:0:0:4,6,0,0:10,0 0,27,228:9:0:0:4,5,0,0:9,0 0,24,196:8:0:0:2,6,0,0:8,0 17 320 . A <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,247:10:0:0:4,6,0,0:10,0 0,27,230:9:0:0:4,5,0,0:9,0 0,24,211:8:0:0:2,6,0,0:8,0 17 321 . T <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,253:10:0:0:4,6,0,0:10,0 0,27,214:9:0:0:4,5,0,0:9,0 0,24,218:8:0:0:2,6,0,0:8,0 17 322 . G <*> 0 . DP=28;DPR=28,0;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,27,226:9:0:0:4,5,0,0:9,0 0,27,223:9:0:0:2,7,0,0:9,0 17 323 . C <*> 0 . DP=28;DPR=28,0;I16=10,18,0,0,1076,42700,0,0,1409,76497,0,0,573,13003,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,27,225:9:0:0:4,5,0,0:9,0 0,27,208:9:0:0:2,7,0,0:9,0 17 324 . T <*> 0 . DP=30;DPR=30,0;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,253:10:0:0:4,6,0,0:10,0 0,27,237:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 325 . A <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,208:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 326 . T <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,216:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 327 . C <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,198:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 328 . A <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,226:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 329 . T <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,237:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 330 . T <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:5,6,0,0:11,0 0,27,231:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 331 . T <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,222:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 17 332 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,27,214:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 333 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,27,223:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 334 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,27,221:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 17 335 . A G,<*> 0 . DP=32;DPR=31,1,0;I16=13,18,1,0,1084,40336,4,16,1589,87297,60,3600,555,11943,0,0;QS=2.98919,0.0108108,0;SGB=-0.556633;RPBZ=-1.67936;MQBZ=0.622171;MQSBZ=-2.25492;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,252,33,252,252:11:0:0:5,6,0,0:11,0,0 0,27,219,27,219,219:9:0:0:4,5,0,0:9,0,0 0,25,245,33,248,245:12:1:0:4,7,1,0:11,1,0 17 336 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1094,39794,0,0,1649,90897,0,0,555,11935,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,212:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 17 337 . C A,<*> 0 . DP=32;DPR=31,1,0;I16=14,17,0,1,1125,42481,5,25,1612,89528,37,1369,536,11590,18,324;QS=2.98113,0.0188679,0;SGB=-0.556633;RPBZ=0.812593;MQBZ=-1.03695;MQSBZ=-2.25492;BQBZ=-1.68353;SCBZ=-0.258065;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255,33,255,255:11:0:0:5,6,0,0:11,0,0 0,17,195,24,198,195:9:1:0:4,4,0,1:8,1,0 0,36,255,36,255,255:12:0:0:5,7,0,0:12,0,0 17 338 . T <*> 0 . DP=30;DPR=30,0;I16=14,16,0,0,1190,47898,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,24,226:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 339 . C <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,185:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 340 . C <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,221:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 341 . T <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,216:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 342 . T <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,210:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 343 . G <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1157,43751,0,0,1649,90897,0,0,554,11978,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,249:11:0:0:5,6,0,0:11,0 0,27,218:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 17 344 . C <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,217:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 17 345 . T <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,221:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 346 . G <*> 0 . DP=31;DPR=31,0;I16=15,16,0,0,1142,43222,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,212:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 347 . G <*> 0 . DP=31;DPR=31,0;I16=15,16,0,0,1124,42252,0,0,1620,90056,0,0,560,12414,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,251:11:0:0:6,5,0,0:11,0 0,24,207:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 17 348 . T <*> 0 . DP=32;DPR=32,0;I16=16,16,0,0,1149,43023,0,0,1680,93656,0,0,562,12556,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,242:11:0:0:6,5,0,0:11,0 0,27,228:9:0:0:5,4,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 17 349 . T <*> 0 . DP=32;DPR=32,0;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,246:11:0:0:6,5,0,0:11,0 0,27,230:9:0:0:5,4,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 17 350 . T <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,249:11:0:0:6,5,0,0:11,0 0,27,230:9:0:0:5,4,0,0:9,0 0,33,255:11:0:0:5,6,0,0:11,0 17 351 . G <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,27,212:9:0:0:5,4,0,0:9,0 0,33,255:11:0:0:5,6,0,0:11,0 17 352 . A <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1162,45664,0,0,1651,92815,0,0,569,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,27,230:9:0:0:5,4,0,0:9,0 0,33,255:11:0:0:5,6,0,0:11,0 17 353 . G <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,27,231:9:0:0:5,4,0,0:9,0 0,30,255:10:0:0:5,5,0,0:10,0 17 354 . A <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,225:9:0:0:4,5,0,0:9,0 0,27,244:9:0:0:5,4,0,0:9,0 0,30,255:10:0:0:5,5,0,0:10,0 17 355 . G T,<*> 0 . DP=28;DPR=27,1,0;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPBZ=0.185772;MQBZ=0.520126;MQSBZ=-1.7696;BQBZ=0.683978;SCBZ=-0.27735;MQ0F=0 PL:DP:DV:SP:DP4:DPR 14,0,200,38,203,231:9:1:0:4,4,0,1:8,1,0 0,27,222,27,222,222:9:0:0:5,4,0,0:9,0,0 0,30,255,30,255,255:10:0:0:5,5,0,0:10,0,0 17 356 . G <*> 0 . DP=27;DPR=27,0;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,228:9:0:0:4,5,0,0:9,0 0,24,201:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 357 . C <*> 0 . DP=28;DPR=28,0;I16=15,13,0,0,1026,39496,0,0,1525,87005,0,0,575,13209,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,24,205:8:0:0:5,3,0,0:8,0 0,30,252:10:0:0:5,5,0,0:10,0 17 358 . A <*> 0 . DP=28;DPR=28,0;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,254:10:0:0:5,5,0,0:10,0 0,24,197:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 359 . G T,<*> 0 . DP=29;DPR=28,1,0;I16=15,13,0,1,1085,42761,10,100,1525,87005,60,3600,552,12620,25,625;QS=2.96032,0.0396825,0;SGB=-0.556633;RPBZ=-0.119611;MQBZ=0.456435;MQSBZ=-1.53333;BQBZ=-1.68246;SCBZ=5.2915;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255,30,255,255:10:0:0:5,5,0,0:10,0,0 0,13,178,21,181,180:8:1:0:5,2,0,1:7,1,0 0,33,255,33,255,255:11:0:0:5,6,0,0:11,0,0 17 360 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:5,5,0,0:10,0 0,24,220:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 361 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:5,5,0,0:10,0 0,24,219:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 362 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,218:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 363 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,213:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 364 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,250:11:0:0:6,5,0,0:11,0 0,24,205:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 365 . G <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,211:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 366 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,211:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 367 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,204:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 368 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,208:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 369 . T G,<*> 0 . DP=28;DPR=27,1,0;I16=16,11,0,1,1037,40275,6,36,1496,86164,60,3600,548,12256,25,625;QS=2.97683,0.023166,0;SGB=-0.556633;RPBZ=0.12395;MQBZ=0.408248;MQSBZ=-1.37784;BQBZ=-1.68703;SCBZ=5.19615;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,250,30,250,250:10:0:0:6,4,0,0:10,0,0 0,15,189,21,192,190:8:1:0:5,2,0,1:7,1,0 0,30,255,30,255,255:10:0:0:5,5,0,0:10,0,0 17 370 . C <*> 0 . DP=28;DPR=28,0;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:6,4,0,0:10,0 0,24,201:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 371 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:6,4,0,0:10,0 0,24,227:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 372 . C <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,215:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 373 . A <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,220:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 374 . T <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,221:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 375 . A T,<*> 0 . DP=31;DPR=30,1,0;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPBZ=-1.45432;MQBZ=0.3849;MQSBZ=-1.26404;BQBZ=-1.68488;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255,36,255,255:12:0:0:7,5,0,0:12,0,0 0,24,218,24,218,218:8:0:0:5,3,0,0:8,0,0 0,18,255,30,255,255:11:1:0:5,5,0,1:10,1,0 17 376 . G <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,24,220:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 377 . T <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1116,41750,0,0,1736,100564,0,0,543,11985,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,24,211:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 17 378 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,186:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 379 . G <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1060,40230,0,0,1678,98882,0,0,541,11897,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,21,187:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 380 . C <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1094,42792,0,0,1678,98882,0,0,539,11797,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,21,184:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 381 . T <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1167,47337,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,21,211:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 382 . T <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1062,40514,0,0,1678,98882,0,0,535,11693,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,21,182:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 383 . T <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1059,39847,0,0,1678,98882,0,0,532,11638,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,21,172:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 384 . A C,<*> 0 . DP=31;DPR=30,1,0;I16=19,11,0,1,1077,39885,4,16,1738,102482,60,3600,504,10988,25,625;QS=2.98419,0.0158103,0;SGB=-0.556633;RPBZ=0.615229;MQBZ=0.262613;MQSBZ=-0.333409;BQBZ=-1.68746;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255,39,255,255:13:0:0:8,5,0,0:13,0,0 0,15,171,21,174,171:8:1:0:6,1,0,1:7,1,0 0,30,255,30,255,255:10:0:0:5,5,0,0:10,0,0 17 385 . C <*> 0 . DP=31;DPR=31,0;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,24,186:8:0:0:6,2,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 17 386 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,191:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 387 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,187:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 388 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,180:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 17 389 . G <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,171:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 17 390 . C <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,162:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 17 391 . A <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,163:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:6,4,0,0:10,0 17 392 . T <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,153:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 17 393 . A <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,133:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 17 394 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,141:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 17 395 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,164:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 17 396 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,158:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 17 397 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,149:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 17 398 . A <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1025,38361,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,144:5:0:0:3,2,0,0:5,0 0,30,255:10:0:0:6,4,0,0:10,0 17 399 . A <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1023,38949,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,140:5:0:0:3,2,0,0:5,0 0,30,255:10:0:0:6,4,0,0:10,0 17 400 . A <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1070,40554,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,159:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 401 . A C,<*> 0 . DP=29;DPR=28,1,0;I16=17,11,0,1,1063,41001,8,64,1587,92523,60,3600,501,11113,25,625;QS=2.97985,0.0201511,0;SGB=-0.556633;RPBZ=-0.478622;MQBZ=0.339683;MQSBZ=0.29364;BQBZ=-1.68267;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255,39,255,255:13:0:0:8,5,0,0:13,0,0 0,15,160,15,160,160:5:0:0:3,2,0,0:5,0,0 0,22,255,30,255,255:11:1:0:6,4,0,1:10,1,0 17 402 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1076,40740,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,149:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 403 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,148:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 404 . G <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,131:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 405 . T <*> 0 . DP=27;DPR=27,0;I16=16,11,0,0,997,37951,0,0,1558,91682,0,0,526,11592,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,12,109:4:0:0:2,2,0,0:4,0 0,30,255:10:0:0:6,4,0,0:10,0 17 406 . G <*> 0 . DP=27;DPR=27,0;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,12,125:4:0:0:2,2,0,0:4,0 0,30,247:10:0:0:6,4,0,0:10,0 17 407 . A <*> 0 . DP=27;DPR=27,0;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,12,125:4:0:0:2,2,0,0:4,0 0,30,255:10:0:0:6,4,0,0:10,0 17 408 . C <*> 0 . DP=28;DPR=28,0;I16=16,12,0,0,1013,38245,0,0,1618,95282,0,0,525,11505,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,12,114:4:0:0:2,2,0,0:4,0 0,30,244:10:0:0:6,4,0,0:10,0 17 409 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,12,131:4:0:0:2,2,0,0:4,0 0,33,255:11:0:0:7,4,0,0:11,0 17 410 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,12,125:4:0:0:2,2,0,0:4,0 0,33,255:11:0:0:7,4,0,0:11,0 17 411 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1022,37928,0,0,1678,98882,0,0,522,11342,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,12,111:4:0:0:2,2,0,0:4,0 0,33,255:11:0:0:7,4,0,0:11,0 17 412 . C T,<*> 0 . DP=30;DPR=29,1,0;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPBZ=-0.40473;MQBZ=0.267261;MQSBZ=-0.293785;BQBZ=-1.6942;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255,42,255,255:15:1:0:8,6,1,0:14,1,0 0,12,124,12,124,124:4:0:0:2,2,0,0:4,0,0 0,33,255,33,255,255:11:0:0:7,4,0,0:11,0,0 17 413 . A <*> 0 . DP=31;DPR=31,0;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,102:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 17 414 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,109:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 17 415 . G <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,110:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 17 416 . G <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1089,41309,0,0,1738,102482,0,0,529,11381,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,114:3:0:0:2,1,0,0:3,0 0,33,252:11:0:0:7,4,0,0:11,0 17 417 . C <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,108:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 17 418 . A <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 17 419 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,112:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 17 420 . A <*> 0 . DP=31;DPR=31,0;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,108:3:0:0:2,1,0,0:3,0 0,36,255:12:0:0:7,5,0,0:12,0 17 421 . A <*> 0 . DP=33;DPR=33,0;I16=19,14,0,0,1211,45581,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,113:3:0:0:2,1,0,0:3,0 0,42,255:14:0:0:8,6,0,0:14,0 17 422 . A <*> 0 . DP=33;DPR=33,0;I16=19,14,0,0,1221,46833,0,0,1887,110523,0,0,535,11707,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,116:3:0:0:2,1,0,0:3,0 0,42,255:14:0:0:8,6,0,0:14,0 17 423 . T <*> 0 . DP=32;DPR=32,0;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,110:3:0:0:2,1,0,0:3,0 0,39,255:13:0:0:8,5,0,0:13,0 17 424 . A <*> 0 . DP=32;DPR=32,0;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,106:3:0:0:2,1,0,0:3,0 0,39,255:13:0:0:8,5,0,0:13,0 17 425 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,249:11:0:0:6,5,0,0:11,0 17 426 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1005,36625,0,0,1647,96123,0,0,544,11912,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,105:3:0:0:2,1,0,0:3,0 0,33,227:11:0:0:6,5,0,0:11,0 17 427 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,242:11:0:0:6,5,0,0:11,0 17 428 . C <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,254:11:0:0:6,5,0,0:11,0 17 429 . T <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,115:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:6,5,0,0:11,0 17 430 . G <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,112:3:0:0:2,1,0,0:3,0 0,33,246:11:0:0:6,5,0,0:11,0 17 431 . G <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1012,37006,0,0,1707,99723,0,0,553,12255,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,101:3:0:0:2,1,0,0:3,0 0,33,224:11:0:0:6,5,0,0:11,0 17 432 . T <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,9,114:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 17 433 . T <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,969,35651,0,0,1587,92523,0,0,559,12467,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,9,112:3:0:0:2,1,0,0:3,0 0,30,229:10:0:0:5,5,0,0:10,0 17 434 . T <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,98:3:0:0:2,1,0,0:3,0 0,30,243:10:0:0:5,5,0,0:10,0 17 435 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1035,38091,0,0,1647,96123,0,0,562,12596,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,103:3:0:0:2,1,0,0:3,0 0,30,237:10:0:0:5,5,0,0:10,0 17 436 . T <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,110:3:0:0:2,1,0,0:3,0 0,27,223:9:0:0:4,5,0,0:9,0 17 437 . T G,<*> 0 . DP=28;DPR=27,1,0;I16=13,14,1,0,990,36832,6,36,1558,91682,29,841,549,12435,16,256;QS=2.9781,0.0218978,0;SGB=-0.556633;RPBZ=-1.36214;MQBZ=-2.88675;MQSBZ=0.6;BQBZ=-1.67909;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255,48,255,255:16:0:0:8,8,0,0:16,0,0 0,9,109,9,109,109:3:0:0:2,1,0,0:3,0,0 0,17,200,24,203,201:9:1:0:3,5,1,0:8,1,0 17 438 . A <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,984,35784,0,0,1587,92523,0,0,565,12707,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,107:3:0:0:2,1,0,0:3,0 0,27,220:9:0:0:4,5,0,0:9,0 17 439 . C <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,107:3:0:0:2,1,0,0:3,0 0,27,224:9:0:0:4,5,0,0:9,0 17 440 . A <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,115:3:0:0:2,1,0,0:3,0 0,27,247:9:0:0:4,5,0,0:9,0 17 441 . G <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,104:3:0:0:2,1,0,0:3,0 0,27,198:9:0:0:4,5,0,0:9,0 17 442 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1079,40643,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,101:3:0:0:2,1,0,0:3,0 0,27,233:9:0:0:4,5,0,0:9,0 17 443 . A <*> 0 . DP=30;DPR=29,0;I16=14,15,0,0,1153,46639,0,0,1647,96123,0,0,532,12036,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,130:3:0:0:1,2,0,0:3,0 0,27,246:9:0:0:4,5,0,0:9,0 17 444 . G <*> 0 . DP=29;DPR=28,0;I16=14,14,0,0,1083,43077,0,0,1587,92523,0,0,533,12103,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,6,98:2:0:0:1,1,0,0:2,0 0,27,227:9:0:0:4,5,0,0:9,0 17 445 . C <*> 0 . DP=30;DPR=29,0;I16=15,14,0,0,1090,42406,0,0,1647,96123,0,0,534,12196,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,122:3:0:0:2,1,0,0:3,0 0,27,219:9:0:0:4,5,0,0:9,0 17 446 . A <*> 0 . DP=30;DPR=29,0;I16=15,14,0,0,1092,42240,0,0,1647,96123,0,0,535,12265,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,127:3:0:0:2,1,0,0:3,0 0,27,232:9:0:0:4,5,0,0:9,0 17 447 . C <*> 0 . DP=29;DPR=28,0;I16=15,13,0,0,1095,43635,0,0,1618,95282,0,0,534,12208,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,125:3:0:0:2,1,0,0:3,0 0,27,235:9:0:0:4,5,0,0:9,0 17 448 . T <*> 0 . DP=29;DPR=28,0;I16=15,13,0,0,1104,44276,0,0,1618,95282,0,0,533,12173,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,130:3:0:0:2,1,0,0:3,0 0,27,240:9:0:0:4,5,0,0:9,0 17 449 . A <*> 0 . DP=28;DPR=27,0;I16=14,13,0,0,1071,43181,0,0,1558,91682,0,0,533,12159,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,6,97:2:0:0:1,1,0,0:2,0 0,27,245:9:0:0:4,5,0,0:9,0 17 450 . G <*> 0 . DP=28;DPR=27,0;I16=14,13,0,0,1053,42427,0,0,1558,91682,0,0,533,12165,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,6,98:2:0:0:1,1,0,0:2,0 0,27,233:9:0:0:4,5,0,0:9,0 17 451 . A <*> 0 . DP=28;DPR=27,0;I16=14,13,0,0,1003,38887,0,0,1558,91682,0,0,533,12191,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,6,100:2:0:0:1,1,0,0:2,0 0,27,244:9:0:0:4,5,0,0:9,0 17 452 . A <*> 0 . DP=31;DPR=30,0;I16=17,13,0,0,1071,40901,0,0,1738,102482,0,0,533,12237,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,121:3:0:0:2,1,0,0:3,0 0,27,225:9:0:0:4,5,0,0:9,0 17 453 . A <*> 0 . DP=31;DPR=30,0;I16=17,13,0,0,1057,40647,0,0,1738,102482,0,0,536,12306,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,129:3:0:0:2,1,0,0:3,0 0,27,225:9:0:0:4,5,0,0:9,0 17 454 . A <*> 0 . DP=31;DPR=30,0;I16=17,13,0,0,1156,45762,0,0,1738,102482,0,0,540,12400,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,9,130:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 17 455 . T <*> 0 . DP=32;DPR=31,0;I16=17,14,0,0,1140,43710,0,0,1775,103851,0,0,543,12419,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,9,124:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 17 456 . G <*> 0 . DP=32;DPR=31,0;I16=17,14,0,0,1154,44790,0,0,1775,103851,0,0,547,12465,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,9,128:3:0:0:2,1,0,0:3,0 0,33,250:11:0:0:5,6,0,0:11,0 17 457 . C <*> 0 . DP=33;DPR=32,0;I16=18,14,0,0,1205,46913,0,0,1835,107451,0,0,552,12538,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,131:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 17 458 . A <*> 0 . DP=33;DPR=32,0;I16=18,14,0,0,1208,46550,0,0,1835,107451,0,0,558,12590,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,122:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 17 459 . T <*> 0 . DP=33;DPR=32,0;I16=18,14,0,0,1153,43773,0,0,1835,107451,0,0,563,12625,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,105:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 17 460 . G <*> 0 . DP=32;DPR=31,0;I16=18,13,0,0,1199,47305,0,0,1775,103851,0,0,568,12642,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,128:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 17 461 . T <*> 0 . DP=32;DPR=31,0;I16=18,13,0,0,1194,47178,0,0,1775,103851,0,0,572,12640,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,127:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 17 462 . G <*> 0 . DP=32;DPR=31,0;I16=18,13,0,0,1169,46001,0,0,1775,103851,0,0,577,12669,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,12,131:4:0:0:3,1,0,0:4,0 0,30,241:10:0:0:5,5,0,0:10,0 17 463 . G <*> 0 . DP=32;DPR=31,0;I16=18,13,0,0,1095,41573,0,0,1775,103851,0,0,583,12729,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,12,126:4:0:0:3,1,0,0:4,0 0,30,221:10:0:0:5,5,0,0:10,0 17 464 . A <*> 0 . DP=32;DPR=31,0;I16=18,13,0,0,1100,41724,0,0,1775,103851,0,0,589,12821,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,12,148:4:0:0:3,1,0,0:4,0 0,30,217:10:0:0:5,5,0,0:10,0 17 465 . C T,<*> 0 . DP=33;DPR=31,1,0;I16=19,12,0,1,1173,45601,4,16,1775,103851,60,3600,589,12909,6,36;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.67982;MQBZ=0.321288;MQSBZ=0.341466;BQBZ=-1.68493;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255,51,255,255:17:0:0:10,7,0,0:17,0,0 0,15,158,15,158,158:5:0:0:4,1,0,0:5,0,0 0,20,224,27,227,224:10:1:0:5,4,0,1:9,1,0 17 466 . A <*> 0 . DP=34;DPR=33,0;I16=20,13,0,0,1268,49686,0,0,1895,111051,0,0,602,13102,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,15,173:5:0:0:4,1,0,0:5,0 0,30,255:10:0:0:5,5,0,0:10,0 17 467 . A <*> 0 . DP=34;DPR=33,0;I16=20,13,0,0,1246,48610,0,0,1895,111051,0,0,608,13194,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,15,177:5:0:0:4,1,0,0:5,0 0,30,251:10:0:0:5,5,0,0:10,0 17 468 . A <*> 0 . DP=35;DPR=34,0;I16=21,13,0,0,1253,48095,0,0,1955,114651,0,0,613,13273,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,174:5:0:0:4,1,0,0:5,0 0,30,251:10:0:0:5,5,0,0:10,0 17 469 . A <*> 0 . DP=35;DPR=34,0;I16=21,13,0,0,1260,49028,0,0,1955,114651,0,0,618,13340,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,165:5:0:0:4,1,0,0:5,0 0,30,255:10:0:0:5,5,0,0:10,0 17 470 . G <*> 0 . DP=35;DPR=34,0;I16=21,13,0,0,1265,48879,0,0,1955,114651,0,0,623,13445,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,167:5:0:0:4,1,0,0:5,0 0,30,238:10:0:0:5,5,0,0:10,0 17 471 . T G,C,<*> 0 . DP=36;DPR=33,1,1,0;I16=21,12,0,2,1220,46380,18,162,1918,113282,97,4969,611,13281,16,256;QS=2.94529,0.0273556,0.0273556,0;VDB=0.96;SGB=0.346553;RPBZ=0.497712;MQBZ=-1.9761;MQSBZ=0.312094;BQBZ=-2.35032;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255,57,255,255,57,255,255,255:19:0:0:12,7,0,0:19,0,0,0 0,15,169,15,169,169,15,169,169,169:5:0:0:4,1,0,0:5,0,0,0 0,19,219,19,221,219,27,222,222,221:11:2:3:5,4,0,2:9,1,1,0 17 472 . T <*> 0 . DP=35;DPR=34,0;I16=21,13,0,0,1234,46640,0,0,1955,114651,0,0,633,13665,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,172:5:0:0:4,1,0,0:5,0 0,30,241:10:0:0:5,5,0,0:10,0 17 473 . G <*> 0 . DP=35;DPR=34,0;I16=21,13,0,0,1303,51953,0,0,1955,114651,0,0,638,13780,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,159:5:0:0:4,1,0,0:5,0 0,30,250:10:0:0:5,5,0,0:10,0 17 474 . G <*> 0 . DP=36;DPR=35,0;I16=22,13,0,0,1279,49235,0,0,2015,118251,0,0,642,13884,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,146:5:0:0:4,1,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 475 . G <*> 0 . DP=36;DPR=35,0;I16=22,13,0,0,1299,49939,0,0,2015,118251,0,0,647,14029,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,159:5:0:0:4,1,0,0:5,0 0,33,253:11:0:0:6,5,0,0:11,0 17 476 . A <*> 0 . DP=36;DPR=35,0;I16=22,13,0,0,1298,50202,0,0,2015,118251,0,0,651,14167,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,177:5:0:0:4,1,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 477 . T <*> 0 . DP=36;DPR=35,0;I16=22,13,0,0,1301,50339,0,0,2015,118251,0,0,655,14349,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,167:5:0:0:4,1,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 17 478 . T <*> 0 . DP=38;DPR=37,0;I16=24,13,0,0,1318,48974,0,0,2135,125451,0,0,656,14422,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:13,7,0,0:20,0 0,18,174:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 479 . A <*> 0 . DP=38;DPR=37,0;I16=24,13,0,0,1397,54499,0,0,2135,125451,0,0,659,14535,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:13,7,0,0:20,0 0,18,184:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 480 . G <*> 0 . DP=37;DPR=36,0;I16=24,12,0,0,1419,57531,0,0,2075,121851,0,0,662,14638,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,18,187:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 481 . G <*> 0 . DP=37;DPR=36,0;I16=24,12,0,0,1382,54524,0,0,2075,121851,0,0,664,14728,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,18,187:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 482 . A <*> 0 . DP=37;DPR=36,0;I16=24,12,0,0,1344,52614,0,0,2075,121851,0,0,666,14854,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,18,164:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 483 . G <*> 0 . DP=37;DPR=36,0;I16=23,13,0,0,1402,55722,0,0,2075,121851,0,0,666,14864,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,18,187:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 484 . A <*> 0 . DP=36;DPR=35,0;I16=23,12,0,0,1329,52551,0,0,2015,118251,0,0,668,14906,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,191:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 485 . G <*> 0 . DP=35;DPR=35,0;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,160:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 486 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1313,51667,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,173:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 487 . G <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1300,50304,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,169:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 488 . A G,<*> 0 . DP=35;DPR=34,1,0;I16=22,12,1,0,1278,48412,4,16,1986,117410,29,841,646,14380,25,625;QS=2.98947,0.0105263,0;SGB=-0.556633;RPBZ=0.594463;MQBZ=-3.36505;MQSBZ=0.10737;BQBZ=-1.69552;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255,54,255,255:18:0:0:12,6,0,0:18,0,0 0,18,177,18,177,177:6:0:0:5,1,0,0:6,0,0 0,23,255,30,255,255:11:1:0:5,5,1,0:10,1,0 17 489 . A <*> 0 . DP=35;DPR=35,0;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,175:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 17 490 . A <*> 0 . DP=36;DPR=36,0;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,188:7:0:0:6,1,0,0:7,0 0,33,255:11:0:0:6,5,0,0:11,0 17 491 . T <*> 0 . DP=36;DPR=36,0;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,178:7:0:0:6,1,0,0:7,0 0,33,255:11:0:0:6,5,0,0:11,0 17 492 . G <*> 0 . DP=35;DPR=35,0;I16=23,12,0,0,1273,48547,0,0,2046,121010,0,0,671,15109,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,175:7:0:0:6,1,0,0:7,0 0,30,251:10:0:0:5,5,0,0:10,0 17 493 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1281,49545,0,0,1986,117410,0,0,672,15156,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,242:9:0:0:4,5,0,0:9,0 17 494 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1324,52440,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,195:7:0:0:6,1,0,0:7,0 0,27,255:9:0:0:4,5,0,0:9,0 17 495 . G <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1265,48677,0,0,1986,117410,0,0,672,15236,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,170:7:0:0:6,1,0,0:7,0 0,27,244:9:0:0:4,5,0,0:9,0 17 496 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,249:9:0:0:4,5,0,0:9,0 17 497 . C <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,164:7:0:0:6,1,0,0:7,0 0,27,239:9:0:0:4,5,0,0:9,0 17 498 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,185:7:0:0:6,1,0,0:7,0 0,27,252:9:0:0:4,5,0,0:9,0 17 499 . T <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,183:7:0:0:6,1,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 500 . A <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,179:7:0:0:6,1,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 17 501 . T <*> 0 . DP=33;DPR=33,0;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,241:9:0:0:5,4,0,0:9,0 17 502 . G <*> 0 . DP=33;DPR=33,0;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,183:7:0:0:6,1,0,0:7,0 0,27,235:9:0:0:5,4,0,0:9,0 17 503 . T <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,177:7:0:0:6,1,0,0:7,0 0,27,234:9:0:0:5,4,0,0:9,0 17 504 . C <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,183:7:0:0:6,1,0,0:7,0 0,27,219:9:0:0:5,4,0,0:9,0 17 505 . C <*> 0 . DP=35;DPR=35,0;I16=24,11,0,0,1217,44421,0,0,2046,121010,0,0,648,14558,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,189:7:0:0:6,1,0,0:7,0 0,27,221:9:0:0:5,4,0,0:9,0 17 506 . A <*> 0 . DP=35;DPR=35,0;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,188:7:0:0:6,1,0,0:7,0 0,27,231:9:0:0:5,4,0,0:9,0 17 507 . C <*> 0 . DP=35;DPR=35,0;I16=24,11,0,0,1231,45137,0,0,2046,121010,0,0,644,14482,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,183:7:0:0:6,1,0,0:7,0 0,27,226:9:0:0:5,4,0,0:9,0 17 508 . A <*> 0 . DP=34;DPR=34,0;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,189:7:0:0:6,1,0,0:7,0 0,27,220:9:0:0:5,4,0,0:9,0 17 509 . C <*> 0 . DP=34;DPR=34,0;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,241:9:0:0:5,4,0,0:9,0 17 510 . A <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1211,44827,0,0,1986,117410,0,0,638,14398,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,187:7:0:0:6,1,0,0:7,0 0,24,221:8:0:0:4,4,0,0:8,0 17 511 . A <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1238,46516,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,195:7:0:0:6,1,0,0:7,0 0,24,233:8:0:0:4,4,0,0:8,0 17 512 . A C,<*> 0 . DP=33;DPR=32,1,0;I16=22,10,0,1,1133,41513,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97766,0.0223368,0;SGB=-0.556633;RPBZ=-1.47079;MQBZ=0.253876;MQSBZ=-0.461593;BQBZ=-1.68442;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255,51,255,255:18:1:0:12,5,0,1:17,1,0 0,21,183,21,183,183:7:0:0:6,1,0,0:7,0,0 0,24,231,24,231,231:8:0:0:4,4,0,0:8,0,0 17 513 . A T,<*> 0 . DP=32;DPR=31,1,0;I16=21,10,1,0,1125,42283,12,144,1806,106610,60,3600,623,14249,15,225;QS=2.97966,0.020339,0;SGB=-0.556633;RPBZ=-1.24609;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.57376;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,37,255,48,255,255:17:1:0:11,5,1,0:16,1,0 0,21,177,21,177,177:7:0:0:6,1,0,0:7,0,0 0,24,233,24,233,233:8:0:0:4,4,0,0:8,0,0 17 514 . A T,<*> 0 . DP=32;DPR=31,1,0;I16=22,9,0,1,1086,40204,16,256,1806,106610,60,3600,627,14381,11,121;QS=2.97127,0.0287253,0;SGB=-0.556633;RPBZ=-1.4628;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.46657;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,34,255,48,255,255:17:1:0:12,4,0,1:16,1,0 0,21,172,21,172,172:7:0:0:6,1,0,0:7,0,0 0,24,235,24,235,235:8:0:0:4,4,0,0:8,0,0 17 515 . C <*> 0 . DP=32;DPR=32,0;I16=22,10,0,0,1050,37704,0,0,1866,110210,0,0,638,14554,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,169:7:0:0:6,1,0,0:7,0 0,24,211:8:0:0:4,4,0,0:8,0 17 516 . C <*> 0 . DP=32;DPR=32,0;I16=22,10,0,0,1109,40651,0,0,1866,110210,0,0,637,14579,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,187:7:0:0:6,1,0,0:7,0 0,24,215:8:0:0:4,4,0,0:8,0 17 517 . T <*> 0 . DP=33;DPR=33,0;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,201:7:0:0:6,1,0,0:7,0 0,24,242:8:0:0:4,4,0,0:8,0 17 518 . G <*> 0 . DP=34;DPR=34,0;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,21,182:7:0:0:6,1,0,0:7,0 0,24,220:8:0:0:4,4,0,0:8,0 17 519 . T <*> 0 . DP=36;DPR=36,0;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,63,255:21:0:0:15,6,0,0:21,0 0,21,177:7:0:0:6,1,0,0:7,0 0,24,224:8:0:0:4,4,0,0:8,0 17 520 . T <*> 0 . DP=36;DPR=36,0;I16=25,11,0,0,1243,45051,0,0,2106,124610,0,0,638,14818,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,63,255:21:0:0:15,6,0,0:21,0 0,21,180:7:0:0:6,1,0,0:7,0 0,24,223:8:0:0:4,4,0,0:8,0 17 521 . C <*> 0 . DP=34;DPR=34,0;I16=25,9,0,0,1281,49527,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,191:7:0:0:6,1,0,0:7,0 0,21,204:7:0:0:4,3,0,0:7,0 17 522 . A <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,185:7:0:0:6,1,0,0:7,0 0,15,170:5:0:0:3,2,0,0:5,0 17 523 . T G,<*> 0 . DP=32;DPR=31,1,0;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPBZ=1.13742;MQBZ=0.179605;MQSBZ=-1.73205;BQBZ=-1.68805;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,44,255,57,255,255:20:1:0:14,5,1,0:19,1,0 0,21,191,21,191,191:7:0:0:6,1,0,0:7,0,0 0,15,166,15,166,166:5:0:0:3,2,0,0:5,0,0 17 524 . T <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1096,39618,0,0,1897,112969,0,0,654,15108,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,194:7:0:0:6,1,0,0:7,0 0,15,150:5:0:0:3,2,0,0:5,0 17 525 . G <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1188,45718,0,0,1897,112969,0,0,656,15120,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,188:7:0:0:6,1,0,0:7,0 0,15,133:5:0:0:3,2,0,0:5,0 17 526 . C <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1154,44014,0,0,1897,112969,0,0,658,15156,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,185:7:0:0:6,1,0,0:7,0 0,15,137:5:0:0:3,2,0,0:5,0 17 527 . A <*> 0 . DP=33;DPR=33,0;I16=25,8,0,0,1220,46386,0,0,1957,116569,0,0,658,15118,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,194:7:0:0:6,1,0,0:7,0 0,18,181:6:0:0:4,2,0,0:6,0 17 528 . G <*> 0 . DP=33;DPR=33,0;I16=25,8,0,0,1268,49968,0,0,1957,116569,0,0,658,15060,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,172:7:0:0:6,1,0,0:7,0 0,18,193:6:0:0:4,2,0,0:6,0 17 529 . C <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1158,44462,0,0,1897,112969,0,0,658,14982,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,187:7:0:0:6,1,0,0:7,0 0,18,184:6:0:0:4,2,0,0:6,0 17 530 . T <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,196:7:0:0:6,1,0,0:7,0 0,18,202:6:0:0:4,2,0,0:6,0 17 531 . T <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,181:7:0:0:6,1,0,0:7,0 0,18,193:6:0:0:4,2,0,0:6,0 17 532 . T <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1161,43607,0,0,1897,112969,0,0,649,14477,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,181:7:0:0:6,1,0,0:7,0 0,18,192:6:0:0:4,2,0,0:6,0 17 533 . C <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1154,44084,0,0,1897,112969,0,0,644,14274,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,178:7:0:0:6,1,0,0:7,0 0,18,180:6:0:0:4,2,0,0:6,0 17 534 . T <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1222,49526,0,0,1837,109369,0,0,640,14104,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,205:7:0:0:6,1,0,0:7,0 0,18,205:6:0:0:4,2,0,0:6,0 17 535 . A G,<*> 0 . DP=31;DPR=30,1,0;I16=24,6,0,1,1080,39870,8,64,1777,105769,60,3600,611,13341,25,625;QS=2.98623,0.0137694,0;SGB=-0.556633;RPBZ=-0.894788;MQBZ=0.182574;MQSBZ=-1.85164;BQBZ=-1.6854;SCBZ=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,41,255,51,255,255:18:1:0:14,3,0,1:17,1,0 0,21,194,21,194,194:7:0:0:6,1,0,0:7,0,0 0,18,189,18,189,189:6:0:0:4,2,0,0:6,0,0 17 536 . C <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1095,40551,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,184:7:0:0:6,1,0,0:7,0 0,18,157:6:0:0:4,2,0,0:6,0 17 537 . C <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1049,38677,0,0,1837,109369,0,0,626,13682,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,172:7:0:0:6,1,0,0:7,0 0,18,183:6:0:0:4,2,0,0:6,0 17 538 . A <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,189:7:0:0:6,1,0,0:7,0 0,18,181:6:0:0:4,2,0,0:6,0 17 539 . T <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,178:7:0:0:6,1,0,0:7,0 0,18,181:6:0:0:4,2,0,0:6,0 17 540 . C <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,177:7:0:0:6,1,0,0:7,0 0,18,178:6:0:0:4,2,0,0:6,0 17 541 . A <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1100,40408,0,0,1897,112969,0,0,601,13241,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,24,180:8:0:0:7,1,0,0:8,0 0,18,159:6:0:0:4,2,0,0:6,0 17 542 . C <*> 0 . DP=33;DPR=33,0;I16=25,8,0,0,1130,41788,0,0,1926,113810,0,0,608,13346,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,27,176:9:0:0:7,2,0,0:9,0 0,18,174:6:0:0:4,2,0,0:6,0 17 543 . C <*> 0 . DP=34;DPR=34,0;I16=25,9,0,0,1211,45383,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,27,194:9:0:0:7,2,0,0:9,0 0,18,188:6:0:0:4,2,0,0:6,0 17 544 . A <*> 0 . DP=33;DPR=33,0;I16=25,8,0,0,1205,45463,0,0,1926,113810,0,0,595,13131,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,24,198:8:0:0:7,1,0,0:8,0 0,18,180:6:0:0:4,2,0,0:6,0 17 545 . A <*> 0 . DP=33;DPR=33,0;I16=25,8,0,0,1197,44795,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,24,196:8:0:0:7,1,0,0:8,0 0,18,184:6:0:0:4,2,0,0:6,0 17 546 . A <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1136,41758,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,21,166:7:0:0:6,1,0,0:7,0 0,18,193:6:0:0:4,2,0,0:6,0 17 547 . A <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1159,43539,0,0,1866,110210,0,0,572,12634,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,21,180:7:0:0:6,1,0,0:7,0 0,18,195:6:0:0:4,2,0,0:6,0 17 548 . A C,<*> 0 . DP=33;DPR=32,1,0;I16=23,9,1,0,1153,42673,9,81,1866,110210,60,3600,561,12489,3,9;QS=2.98607,0.0139319,0;SGB=-0.556633;RPBZ=1.57584;MQBZ=0.253876;MQSBZ=-2.34521;BQBZ=-1.68939;SCBZ=3.80814;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,44,255,54,255,255:19:1:0:13,5,1,0:18,1,0 0,21,181,21,181,181:7:0:0:6,1,0,0:7,0,0 0,21,211,21,211,211:7:0:0:4,3,0,0:7,0,0 17 549 . T G,<*> 0 . DP=32;DPR=31,1,0;I16=23,8,0,1,1135,42143,20,400,1806,106610,60,3600,532,11720,25,625;QS=2.96918,0.0308166,0;SGB=-0.556633;RPBZ=-0.487556;MQBZ=0.258065;MQSBZ=-2.29695;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,34,255,51,255,255:18:1:0:13,4,0,1:17,1,0 0,21,168,21,168,168:7:0:0:6,1,0,0:7,0,0 0,21,208,21,208,208:7:0:0:4,3,0,0:7,0,0 17 550 . T <*> 0 . DP=32;DPR=32,0;I16=23,9,0,0,1056,37314,0,0,1866,110210,0,0,549,12177,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,150:7:0:0:6,1,0,0:7,0 0,21,220:7:0:0:4,3,0,0:7,0 17 551 . G <*> 0 . DP=31;DPR=31,0;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,172:7:0:0:6,1,0,0:7,0 0,21,208:7:0:0:4,3,0,0:7,0 17 552 . C <*> 0 . DP=30;DPR=30,0;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:11,5,0,0:16,0 0,21,167:7:0:0:6,1,0,0:7,0 0,21,208:7:0:0:4,3,0,0:7,0 17 553 . A <*> 0 . DP=30;DPR=30,0;I16=21,9,0,0,1006,36136,0,0,1746,103010,0,0,528,11780,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:11,5,0,0:16,0 0,18,150:6:0:0:5,1,0,0:6,0 0,24,203:8:0:0:5,3,0,0:8,0 17 554 . A <*> 0 . DP=30;DPR=30,0;I16=21,9,0,0,1008,36694,0,0,1746,103010,0,0,521,11595,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:11,5,0,0:16,0 0,18,143:6:0:0:5,1,0,0:6,0 0,24,221:8:0:0:5,3,0,0:8,0 17 555 . A <*> 0 . DP=30;DPR=30,0;I16=20,10,0,0,1022,36374,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,150:6:0:0:5,1,0,0:6,0 0,21,211:7:0:0:4,3,0,0:7,0 17 556 . C <*> 0 . DP=29;DPR=29,0;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,158:6:0:0:5,1,0,0:6,0 0,18,186:6:0:0:4,2,0,0:6,0 17 557 . A <*> 0 . DP=27;DPR=27,0;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,157:6:0:0:5,1,0,0:6,0 0,18,186:6:0:0:4,2,0,0:6,0 17 558 . A <*> 0 . DP=27;DPR=27,0;I16=18,9,0,0,956,35872,0,0,1589,94441,0,0,502,10906,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,153:6:0:0:5,1,0,0:6,0 0,18,177:6:0:0:4,2,0,0:6,0 17 559 . C A,<*> 0 . DP=27;DPR=26,1,0;I16=18,8,0,1,915,33775,14,196,1560,93600,29,841,473,10141,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPBZ=-1.02726;MQBZ=-5.09902;MQSBZ=-1.41421;BQBZ=-1.54776;SCBZ=5.09902;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255,45,255,255:15:0:0:9,6,0,0:15,0,0 0,4,116,15,119,123:6:1:0:5,0,0,1:5,1,0 0,18,169,18,169,169:6:0:0:4,2,0,0:6,0,0 17 560 . C <*> 0 . DP=28;DPR=28,0;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,160:6:0:0:5,1,0,0:6,0 0,21,181:7:0:0:5,2,0,0:7,0 17 561 . A <*> 0 . DP=28;DPR=28,0;I16=19,9,0,0,973,35555,0,0,1649,98041,0,0,491,10571,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,158:6:0:0:5,1,0,0:6,0 0,21,194:7:0:0:5,2,0,0:7,0 17 562 . C <*> 0 . DP=28;DPR=28,0;I16=19,9,0,0,1014,38392,0,0,1649,98041,0,0,488,10518,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,153:6:0:0:5,1,0,0:6,0 0,21,187:7:0:0:5,2,0,0:7,0 17 563 . A <*> 0 . DP=27;DPR=27,0;I16=18,9,0,0,903,32513,0,0,1589,94441,0,0,485,10445,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,15,149:5:0:0:4,1,0,0:5,0 0,21,179:7:0:0:5,2,0,0:7,0 17 564 . C <*> 0 . DP=27;DPR=27,0;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,15,121:5:0:0:4,1,0,0:5,0 0,21,182:7:0:0:5,2,0,0:7,0 17 565 . G <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,842,27104,0,0,1769,105241,0,0,479,10389,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,18,100:6:0:0:4,2,0,0:6,0 0,21,154:7:0:0:5,2,0,0:7,0 17 566 . C A,<*> 0 . DP=29;DPR=28,1,0;I16=16,12,1,0,920,33998,9,81,1649,98041,60,3600,454,9734,25,625;QS=2.98321,0.016791,0;SGB=-0.556633;RPBZ=0.239193;MQBZ=0.188982;MQSBZ=-1.19024;BQBZ=-1.43942;SCBZ=-0.188982;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,38,255,48,255,255:17:1:0:8,8,1,0:16,1,0 0,15,155,15,155,155:5:0:0:3,2,0,0:5,0,0 0,21,170,21,170,170:7:0:0:5,2,0,0:7,0,0 17 567 . C <*> 0 . DP=30;DPR=30,0;I16=17,13,0,0,956,34312,0,0,1769,105241,0,0,496,10638,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,18,156:6:0:0:3,3,0,0:6,0 0,21,194:7:0:0:5,2,0,0:7,0 17 568 . C <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1060,40304,0,0,1709,101641,0,0,497,10663,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,18,179:6:0:0:3,3,0,0:6,0 0,21,193:7:0:0:5,2,0,0:7,0 17 569 . T <*> 0 . DP=30;DPR=29,0;I16=16,13,0,0,1061,41321,0,0,1709,101641,0,0,497,10671,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,18,190:6:0:0:3,3,0,0:6,0 0,21,213:7:0:0:5,2,0,0:7,0 17 570 . T <*> 0 . DP=30;DPR=29,0;I16=16,13,0,0,962,34938,0,0,1709,101641,0,0,497,10711,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,18,162:6:0:0:3,3,0,0:6,0 0,21,195:7:0:0:5,2,0,0:7,0 17 571 . C <*> 0 . DP=31;DPR=30,0;I16=17,13,0,0,1069,40739,0,0,1769,105241,0,0,497,10783,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,18,159:6:0:0:3,3,0,0:6,0 0,21,193:7:0:0:5,2,0,0:7,0 17 572 . A <*> 0 . DP=31;DPR=30,0;I16=18,12,0,0,1092,41268,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,21,204:7:0:0:4,3,0,0:7,0 0,18,175:6:0:0:5,1,0,0:6,0 17 573 . A <*> 0 . DP=31;DPR=30,0;I16=18,12,0,0,1060,38698,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,21,201:7:0:0:4,3,0,0:7,0 0,18,178:6:0:0:5,1,0,0:6,0 17 574 . C A,<*> 0 . DP=31;DPR=29,1,0;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPBZ=-0.173514;MQBZ=-5.38516;MQSBZ=-1.22474;BQBZ=-1.68578;SCBZ=3.60588;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255,48,255,255:16:0:0:8,8,0,0:16,0,0 0,9,170,21,173,177:8:1:0:5,2,0,1:7,1,0 0,18,173,18,173,173:6:0:0:5,1,0,0:6,0,0 17 575 . T C,<*> 0 . DP=30;DPR=28,1,0;I16=17,11,0,1,1048,41548,9,81,1680,100800,29,841,480,10426,25,625;QS=2.96786,0.0321429,0;SGB=-0.556633;RPBZ=-0.119685;MQBZ=-5.2915;MQSBZ=-1.19024;BQBZ=-1.68121;SCBZ=3.53589;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255,48,255,255:16:0:0:8,8,0,0:16,0,0 0,13,200,21,203,202:8:1:0:5,2,0,1:7,1,0 0,15,163,15,163,163:5:0:0:4,1,0,0:5,0,0 17 576 . G <*> 0 . DP=30;DPR=29,0;I16=17,12,0,0,1043,39581,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,24,208:8:0:0:5,3,0,0:8,0 0,15,151:5:0:0:4,1,0,0:5,0 17 577 . G <*> 0 . DP=30;DPR=29,0;I16=17,12,0,0,997,37255,0,0,1709,101641,0,0,509,11155,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,24,204:8:0:0:5,3,0,0:8,0 0,15,146:5:0:0:4,1,0,0:5,0 17 578 . G <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:7,9,0,0:16,0 0,24,198:8:0:0:5,3,0,0:8,0 0,15,151:5:0:0:4,1,0,0:5,0 17 579 . G <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1038,38820,0,0,1769,105241,0,0,523,11335,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,24,224:8:0:0:4,4,0,0:8,0 0,15,144:5:0:0:4,1,0,0:5,0 17 580 . A C,<*> 0 . DP=30;DPR=29,1,0;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPBZ=1.32953;MQBZ=0.185695;MQSBZ=-1.06904;BQBZ=-1.69093;SCBZ=-0.267102;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,34,255,48,255,255:17:1:0:7,9,1,0:16,1,0 0,24,221,24,221,221:8:0:0:4,4,0,0:8,0,0 0,15,155,15,155,155:5:0:0:4,1,0,0:5,0,0 17 581 . A <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:8,10,0,0:18,0 0,24,223:8:0:0:4,4,0,0:8,0 0,15,153:5:0:0:4,1,0,0:5,0 17 582 . C G,<*> 0 . DP=31;DPR=30,1,0;I16=15,15,1,0,1080,39870,8,64,1769,105241,60,3600,519,11211,15,225;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.34259;MQBZ=0.182574;MQSBZ=-1.0328;BQBZ=-1.68266;SCBZ=-0.262467;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,41,255,51,255,255:18:1:0:7,10,1,0:17,1,0 0,24,207,24,207,207:8:0:0:4,4,0,0:8,0,0 0,15,151,15,151,151:5:0:0:4,1,0,0:5,0,0 17 583 . T <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1135,43913,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,24,238:8:0:0:4,4,0,0:8,0 0,15,163:5:0:0:4,1,0,0:5,0 17 584 . C <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1069,39521,0,0,1798,106082,0,0,544,11644,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,209:8:0:0:4,4,0,0:8,0 0,15,157:5:0:0:4,1,0,0:5,0 17 585 . A <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,211:8:0:0:4,4,0,0:8,0 0,15,157:5:0:0:4,1,0,0:5,0 17 586 . T <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1091,39939,0,0,1798,106082,0,0,553,11845,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,212:8:0:0:4,4,0,0:8,0 0,15,156:5:0:0:4,1,0,0:5,0 17 587 . C <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1078,39466,0,0,1798,106082,0,0,557,11975,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,204:8:0:0:4,4,0,0:8,0 0,15,155:5:0:0:4,1,0,0:5,0 17 588 . A <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,222:8:0:0:4,4,0,0:8,0 0,15,164:5:0:0:4,1,0,0:5,0 17 589 . A <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1156,43908,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,235:8:0:0:4,4,0,0:8,0 0,15,165:5:0:0:4,1,0,0:5,0 17 590 . C <*> 0 . DP=32;DPR=32,0;I16=17,15,0,0,1103,41355,0,0,1858,109682,0,0,574,12576,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,194:8:0:0:4,4,0,0:8,0 0,18,175:6:0:0:4,2,0,0:6,0 17 591 . A <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1164,44088,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,209:7:0:0:3,4,0,0:7,0 0,18,188:6:0:0:4,2,0,0:6,0 17 592 . A <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1121,42193,0,0,1798,106082,0,0,583,12795,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,215:7:0:0:3,4,0,0:7,0 0,18,182:6:0:0:4,2,0,0:6,0 17 593 . C A,<*> 0 . DP=31;DPR=30,1,0;I16=16,14,0,1,1071,39925,7,49,1769,105241,29,841,561,12253,25,625;QS=2.97021,0.0297872,0;SGB=-0.556633;RPBZ=0.559355;MQBZ=-3.80789;MQSBZ=-0.0464238;BQBZ=-1.57464;SCBZ=3.67454;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255,54,255,255:18:0:0:9,9,0,0:18,0,0 0,12,184,18,187,185:7:1:0:3,3,0,1:6,1,0 0,18,174,18,174,174:6:0:0:4,2,0,0:6,0,0 17 594 . A G,<*> 0 . DP=33;DPR=32,1,0;I16=16,16,1,0,1161,42757,4,16,1858,109682,60,3600,572,12672,15,225;QS=2.99359,0.00641026,0;SGB=-0.556633;RPBZ=-0.998367;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68954;SCBZ=-0.253876;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255,51,255,255:18:1:0:8,9,1,0:17,1,0 0,21,205,21,205,205:7:0:0:3,4,0,0:7,0,0 0,24,213,24,213,213:8:0:0:5,3,0,0:8,0,0 17 595 . A <*> 0 . DP=33;DPR=33,0;I16=17,16,0,0,1136,40412,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,198:7:0:0:3,4,0,0:7,0 0,24,218:8:0:0:5,3,0,0:8,0 17 596 . A G,<*> 0 . DP=33;DPR=32,1,0;I16=16,16,1,0,1061,37187,8,64,1858,109682,60,3600,590,12952,1,1;QS=2.98564,0.0143627,0;SGB=-0.556633;RPBZ=1.68146;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68357;SCBZ=-0.253876;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,41,255,51,255,255:18:1:0:8,9,1,0:17,1,0 0,21,169,21,169,169:7:0:0:3,4,0,0:7,0,0 0,24,231,24,231,231:8:0:0:5,3,0,0:8,0,0 17 597 . C <*> 0 . DP=33;DPR=33,0;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,204:7:0:0:3,4,0,0:7,0 0,24,220:8:0:0:5,3,0,0:8,0 17 598 . T <*> 0 . DP=33;DPR=33,0;I16=16,17,0,0,1219,47333,0,0,1918,113282,0,0,597,13029,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,217:7:0:0:3,4,0,0:7,0 0,27,242:9:0:0:5,4,0,0:9,0 17 599 . T <*> 0 . DP=33;DPR=33,0;I16=16,17,0,0,1182,43598,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,197:7:0:0:3,4,0,0:7,0 0,27,247:9:0:0:5,4,0,0:9,0 17 600 . G <*> 0 . DP=32;DPR=32,0;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,194:7:0:0:3,4,0,0:7,0 0,24,232:8:0:0:4,4,0,0:8,0 bcftools-1.21/test/mpileup/mpileup.4.sam000066400000000000000000003071111467060157400202360ustar00rootroot00000000000000@HD VN:1.0 SO:coordinate @SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human @RG ID:ERR229776 LB:HG00102_I_bc_pelib_1019 SM:HG99999 PI:497 CN:MPIMG PL:ILLUMINA DS:SRP001294 ERR229776.22049853 163 17 1 29 80S21M = 115 213 AGGCTCAGACTCCTTTCTCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGGCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTG BDBDHECFF@D=DA>CIJIF8E>HBEEBH@AA8>GH@BIJI;?CC95@@?*2-67=6?$6ABDGD6GGHKGEGHIJIH=BFIKI:DEADBH>CFIE MD:Z:21 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ihg\aehjhYcd`cag]behd ERR229776.4635304 99 17 1 29 9S92M = 250 348 TTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACG BFFKGHHHIKIIIKIKLKIILHMKJJLLMILJJJMLJJNKLLMKKJLJKNKLKILNKLKMLINLMNLMNKJJKLNKMKFAEHGMKPLHFGJIMIKFFFE@; MD:Z:92 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@jhhhjhjkjhhkgljiikklhkiiilkiimjkkljjikijmjkjhkmjkjlkhmklmklmjiijkmjlje`dgfljokgefihlhjeeed_Z ERR229776.76124411 163 17 1 29 12S89M = 253 351 AACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCC @BDIFEFFEBBGJIHGJHEIJHGJJKIIIIJKHHIIIJKICKHE@>1;<=E?CG?F X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR229776.71066602 99 17 35 60 101M = 291 355 ATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCT BEFHDHJHHHFGLIJIJKKLJKLKKMJIIHJLKMJJLMGGLJMJMMMEJMMKKMMKJ?LKLJMHNJIIMHCFHGMFCIJDHJICAIDJJFIHGGIBBHEEI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229776.57643739 113 17 39 37 101M * 0 0 CAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCC DEEFHE@C?HCHHAIJIIJIHCJEIE;JHFEEFHKFJFJIEGIJGH>9KJD@;EFCJIFA=JFICKIDCFJGFC?IIJHHHKHB@IICIICGCGJGDDH?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.24343576 163 17 62 60 101M = 322 360 GTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAA @DCDHCFB>,,FGDGFHGC@FHFIHGIKH@2JGH@JGJ?EJHCA5?BLIHEJHIGFEB@BG;BBEDGIEDGGGL;FGFI;A37F9F2=@JCDKHJGAIGFEEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.48988007 99 17 115 60 101M = 371 356 CAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAG ?GDCCIGFKGFKGHKKHGIKJIIKGJHIACKFGHCKHJJJFIILGFGMK@CKFIHHJHI>JIFJMEGADJG>FEHJIIIFHJHIMDHKGIH?CJGGFFIE8 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.22049853 83 17 115 29 1S100M = 1 -213 CCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTA ##IDEBEBHKIDCIFDIFGKD?EHA>BA;GJHIABEGEFGIBDGIKGJMGJIJKHGHKJALJJIJ@DCECE>EIIIHHIKDEFHIEHGHHGHGFEECCD@7 X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR999999 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.6535575 163 17 136 60 101M = 400 364 GTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCCTGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAG @:9D&@9/0<98DBCCGCDG:?E=>D><+/;7A:=HE71)61>4:KDDIKLJJGJH=6GAIGEIHCHGB@?>HBFHGHBGDFKFGKHGFCFFGBBEJFIJMIFIHJJJLIDFF@HDKHEHGFEHLHHDEFDB X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.74734077 163 17 164 60 101M = 421 357 TGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCGCCGCCCAAAGCCACGCCCATGTCCAGCTTATTCTGCCC 7+>C1A5?-3&B<:EA:(86>A4F8=B<7>7D52@7=>CAE5DK.DCF>(-706B=ACA>D<@IE4:D;CG;@BH9@GH@CCJ@G=B@;ED9E@BHDBFHGI;5ABFHFIG=FCE/=GHHEJGJF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H ERR229776.86942903 99 17 232 60 71M1I29M = 471 339 CAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTT AGHIGIEGD>BGHFHHIKKILKMIIIHIKHJKLCEFJJFMDLJIFHKLLKDJGBEGGJ?@GFIIKIH?GGHDDACIB?>DDJFGII1?,9ED*@>D@FCE= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR229776.4635304 147 17 250 29 53M1I47M = 1 -348 CAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTT EIGGGHHHHCJICGIMGCJGHKCFDJOJJKKIJKKKJIKJJMIIJJJHEHIGILLLLGLBGDJJJLKGIKHGIIKHHJHHKIFHHCG;HFBCGFBEFCDGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG ERR229776.76124411 83 17 253 29 50M1I50M = 1 -351 CTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA DDFFFGHJIGHINGDIGDJIJAINKELOIJLKKKKKMJLKKGJKJKLNKKNMMMKLBLJLLLNMMJKKJKKJJJKKJLLIJJHE@KJJJKFHIHFEIIHFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.72556128 147 17 262 60 41M1I59M = 22 -339 CCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAA DDFJEGJGC@IKEINIFFMHKHIJKKKIIMJKJJJLKKMJJLKKMJLCKKFKKMLLJKJIIKKIIKJHKLGHIGC>HHIJKFHHHGGIJGBEEJAEEIFEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG ERR229776.73749010 147 17 283 60 5S20M1I75M = 28 -349 AAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGT ######G?<7G9;+@-DEI=CHOHKOFBHE9BHKFE>JHDH9?GHFDCBKCIHA;E=C;9>@A7HA?;AGADHBGHGG@@:>8HG?D9DF6/;@=>:BBA;FEFGH:A7E<&>HAJEIEKKKJGMIJGILKMGNLLKLKIEIJHDIEFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.65476258 99 17 324 60 101M = 548 324 TATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATA BFFFGHHHHKIJKELKKKJJJLKLIIJIKLLJJLJMLMMNKLLKFJMNMKKJMKKLMNLLKKNLKLMKKKKLLKJNNNLILKLMJNLLKLKIEIKHGHGFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.44063798 163 17 331 60 101M = 608 377 TAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGG @92:9C:E>:EFG>H@ X0:i:1 X1:i:0 MD:Z:0A100 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ZS@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.59467859 147 17 359 60 101M = 159 -300 GAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCAT DGCDGIEEDKK>LIKHIGMJFHLNJFHLIJAJIIFMMHDIJHGIHIJLIC?LJIEDCA=<3AJIHID)MJGD=@?<8*4JCCA8@928-=92)2@975E)BFE8-;L>CFC>8K?E=8''?@9A>6C694*%;,/44* X0:i:1 X1:i:0 MD:Z:4A25A63C5T0 RG:Z:ERR229776 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.70199275 99 17 391 29 101M = 711 374 ATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAAT ?EFGGHHFFIEIIEF?C@ABICJICEIJJJLLJJM?H>HHCFI:G>AEHJILLFHGCMJGLKEM>-5A8BKE;JIJHFH4AEIAGMJDF@EHKJHJLHD9JKJN?JLFAG=GMGKKJIAJAJGHI@JGIKKIMHLIIGDILHIF>CGJJLGDC8DHHLGFGFE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.5711913 163 17 409 60 101M = 646 337 TTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACAC <@CDFD@A?HIIGFJKJLLIFIFCGIFEEDF@KMC?EI=<<GGCDEEFDD7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.22701711 163 17 421 29 101M = 699 375 AATAATACTGGTTTATGACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGGAATGAAGACATATGTCCACACAAAAACCTGTTC 93:<>>FC'?IHGIKH7KCHCGJFFJHEFCHJJMCLAHJDHKHMGHMLMEF@IBFIHI@DA:HCIGFA83>=0HHEG7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.52216469 163 17 454 60 101M = 693 339 ATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAA @CEEFFBFE:<>:MEMIMED1N?LLQKQD9)@GNLKB@GHGFA;>A>D>;A;H=?B5DIEAFEC>-(7@C8BAD5>7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.82457097 99 17 474 60 101M = 695 321 GGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAAC A?HGGHHFIGHIJFJLLDEJLJKIJIIIGJLMJHIHKMNNNJMNLJJMKKJJMKMMMLLLNJJMKKLKJMKNNNNIKKIIKMJMHGFKGHC?FEHLDFGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.93698964 99 17 499 60 101M = 735 336 TATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTT BFFGHGFHFHEIKKKLIKLIIJLJJKKLJLIMKKMMJKMKKMKKMKNNMNKLLMKNNKKNKMKJKKBKJIOJKKGINHGEGHHGMIJIIJIGJHFIBFDHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CC ERR229776.17900575 99 17 527 60 101M = 760 333 AGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCAC BEGKGHGLHFDIIGIIKILLLLIKKLJMLIJKILJIKJBMMMNKLKMKNLMMMJLJMMKKKJLIJMHKMIEMJHJICJFDFHIHJGGGKDIIGJGHIDEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.65476258 147 17 548 60 101M = 324 -324 ATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAA BCGGGE@GIAJGDGIHAIGFKNMJKKJKJHKLJGKKJJLKKJJHIKKJJKGJJJKILGGHBHFBHHJIHIGF:KGBJIEJKFFHGAGGHGBBHD;DCEEEA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CA ERR229776.83749675 163 17 553 60 100M1S = 783 330 AAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCT ?<:GH:?I59=G@JHHDC3D'6@?ACFHI:E?>;BG=BECFIBH:6?E<6?GDEDHDCHDE65?=GE## X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@ ERR229776.19017039 99 17 560 60 101M = 839 368 CACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGGTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACAT ?GDB=1GFFK:GHGH=F?G=CHJJ?DJLGGDGCCC6CIEA?.@E9 X0:i:1 X1:i:0 MD:Z:44T56 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.78639790 147 17 590 60 101M = 335 -355 CAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTC CFDGCCHEBGDGFDBKCACBCBC?HKIKDGKLEJJGDHMDG45?IIFIHDEDHIBHA:94'ECEFHC=EH>BFGB@@?:?CEFFFBKJG=JD>EIGFGHHLGBECIKJJ?JLBG=JHGHIIIJMHKKIJGIIC5FGIJGGEIGGFEFIEEHE7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G@ ERR229776.47649789 147 17 647 60 101M = 392 -355 AACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGG 68BIAGJE?C?=8JI=5@EIEJHLJJIHGGGBGC?=.?JBAAG=A4EAHJ=FFJJJKJLHH@KJIDHB=HF>?FF>HF@FH;DGI@GAGF7@;@=;3?DBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.52216469 83 17 693 60 101M = 454 -339 CCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTG C=DHEIHFFLIANGFAKIJLMIILOKJJKLLKKKKNKKMMKLKMKKNNLLKKMMMLLNHKMKMKJJJCKLKJIJILKIMJLLKGJLKFIIGHKFFHFKEHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.82457097 147 17 695 60 101M = 474 -321 GTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGT ?HEFAC>LEAG@C=A@GKKCFHLJJKKJHFCHGKJJJEIGJMJEKFIJJJCHIJKMIFJIFFJJI@FHGH>>;HEEIFCJJ=DJGCGBBEEACFBICEDDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.22701711 83 17 699 29 3S98M = 421 -375 TGTGAAAGAAGCCGGACTCCCAGGGCAACACCCTATCCGACTGTTTCCTGGGAAAGTCTGGCAACGGCCACACCATTGAGACAGACAACAGGTGAGTGGTT ####FCGEAFD7::.:DB;'=CB+D@BFFF;2C<,8-%H@C@FI;F-+KIHDCB@57CID<*A4/)G:)ID0IJGKIDIDGEH8<+==FLAEGCKEFEDD? XC:i:98 MD:Z:16A11A5T9A13A6A16A15 RG:Z:ERR229776 AM:i:29 NM:i:7 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.70199275 147 17 711 29 46S55M = 391 -374 CAGACAAATGAAACTCAAACAAGTTCCCCCGTGTTAAAGAAAACGAACTCACAGGGCAGCACACTATCTGACTGTTTCATGGGAAAGTCTGGAAGCGGAAA ##############################################CC<+2:::)HD@(8<6C?A;?>=>,'7(>@3>6><=<1;+7:8>A4@9%.*<07* XC:i:56 MD:Z:12A35A3C2 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.93698964 147 17 735 60 101M = 499 -336 ACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT AEHFGJG:@GHHIHFI@;>JHHEEH@IJJCKJFJJKMJJIIJJHIJGI=HFHGJKLIEFFKICDIDKBIKE@IIIJHGIKKHIGIDIFIG<IFKMJMBGKDFFJF@CGBBIGINHJEJI?FFBDILDLDDILIFGA7)?EEHLIMIHFIFHHHIFDFJD X0:i:1 X1:i:0 MD:Z:83T5G11 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR229776.92236775 81 17 758 37 101M * 0 0 AACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAA A?>FGG@BDCFFJIJIMIKIMFFIKJILIIKJNIKJILJMJKKMLMLMLMJIIJFINMLFJGLKJKJJHIKKJLJHIJJLIIHDJKIJGIEFGFGHGHDFB X0:i:1 X1:i:0 MD:Z:70T5G24 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AA ERR229776.17900575 147 17 760 60 101M = 527 -333 CGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGA +EGGCFD>EEFAJIIIJHMHEEJJHKIHJIMDCHHKKJJJJMMEEEKMKIBHBLKLKCIJKLIJGHCAGIFDDF>HFHFIHECEGDF?GEB?EFCFEEIEB X0:i:1 X1:i:0 MD:Z:68T5G26 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.83749675 83 17 783 60 101M = 553 -330 ACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAG EEICDIHLCGFDCHH>DFHFKGDCNEKJJLHLLG;KIIIDLJEEJD@IC=D=0GMFLIJLCJHHCHFEHIIHHJHIHDFIHKHGHKH>HHAFDE=GEF=H: X0:i:1 X1:i:0 MD:Z:45T5G49 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.63559677 147 17 833 60 101M = 594 -339 TATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTG FDHFHIHEF@FDD;5AC::ELBGCBHE3DKIHEHMFAHLE=BACIGH>IFB7FEHBC=G>KHFCHIFFGJDHEFFBB@BACFCCD@ X0:i:1 X1:i:0 MD:Z:1G99 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:[YZA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.19017039 147 17 839 60 11S90M = 560 -368 CTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGG ############GJE:GEE?9)D<=B?09>.>/1?ACBCBIJIA@@?5FEEC9HL<<8?7,B?@@@BGHGC9BHIHGI:GG@BHHCFGGJ<3ED;;CDAB@ X0:i:1 X1:i:0 XC:i:90 MD:Z:90 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.98760722 163 17 840 60 101M = 1103 363 ATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCT CBG@;DACF=HDJFJJCMJH@JGIKKIFDFFFHHEGEDHKHGCGJJICAB=?AIIIGGEG X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229776.516742 163 17 845 60 101M = 1152 407 GGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGT A;>HF=GAIHGGH?FIEHGE9EFCIEA=@@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBFH ERR229776.55719080 99 17 994 60 101M = 1282 388 TCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGG BFHIGFHLHHEKIIJKKKHIJKIKILAKLJJLJKJJMKKLJLMMJMLKKNKKMLKLKNNNKMMMKIKMJNKMMMNGHHJFHHIKHIIIKHIHCGMGHDIEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.77830097 163 17 1036 60 101M = 1255 319 CTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTT BIEBGCCHCBCHHH,=FICDJKHCGDGJHJJKHFIIJKLLIKLGLGKLMMDHLJJDLFIKIDIDIKIGJIFHHGFHEHJH?JIIFJFFIIFLIJHGHGGIB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@ ERR229776.3695912 99 17 1042 60 101M = 1118 176 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIHHHKIKGJKLJIKLLLIMMMMMMJKLMMKLMMNKLNMNNKLLJJNLMLKJKJLMKJLJJHKJHHHHLHFJIHHHIKIKINJKIHJIIMJGEHDED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.54641833 99 17 1042 60 101M = 1321 379 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIGGGKIKGGKKHAHLJLIMMMMMLJKLMMKKMMMFLLMNMJNMKJMJMLKJKJLMKJLJJHKJHGHHJHFJIJHHIKIKINJKIHJIIMJGEHDEF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.90795085 163 17 1066 60 101M = 1297 331 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTT BGHGHEDHGDCHJGJHIJI?JGJIHHKIKIGHHIKLIFKIIJIHL=HIKJCIGLLHIHKJMLKIEBEHJMLJDMIJKJMIKLDHKCJJGFDHHGGGEFFCB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:JOOLJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BCEGEE ERR229776.51118640 99 17 1069 60 101M = 1370 401 AAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCAT BHFHIJJHJKIKJJKKLKHLLJJMKLKJJJKLMJKLJJJKMMFJGKKMLJMMKKLJKMNLMNNKLMNKLKLKMKLMLLIGLLIKNKKLKJCKHFEEFCFGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.57580585 163 17 1077 60 101M = 1316 339 AAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTA BGHGEEE@G>9JHEGHGIFFHHHJKHHIFBAIIFGHHIJKHIJKIIKJIKGJKMLJKKNKKBLDLJKLJLKKJKHLIKLKLKIKLFLKLFIJJEIJGHFDE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CFFB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.82642257 163 17 1081 60 101M = 1336 355 GAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCT BGHGHH@JEB@JGHHEGGGHJHBJHHIFIICIA>HDJIKJIIJIILLKJLGJJLMJJGLJLGKIHJ=JJKLLMJKKLKFMKLLLLFIJKIKKKKHGGFGGJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@L ERR229776.30538656 163 17 1087 60 101M = 1321 334 CTCACTGTATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAG A?BHJEKFGG??IKKKAEIKJJLLKLLEHKLKIHIJIILEGGEG? X0:i:1 X1:i:0 MD:Z:7G93 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.87113255 99 17 1096 60 101M = 1361 365 TATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTAC ?EFGGFHHJHFGIAHIIFKLLKJKLJJKIJKMKLMMJJMNKJMEHHFIEDIKLKLGLLKLLLLKLKJHKJJKKHKFIKD;JCGEIGDIIDK=4CEDEFAEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.98760722 83 17 1103 60 101M = 840 -363 GATACAGGTTGAGGATCCATTATCTGGAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCA EFFFGLHGHJLNKLKJGLLNLILLLIAKKKJLNKJHJMJNIJKDNNNKLLKNNNJMMJMNNNNLKJIJMMMJIJKJKLMLJJEFHHHCIJAGFFHLDIHE? X0:i:1 X1:i:0 MD:Z:26A74 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.37017046 99 17 1113 60 101M = 1339 326 GAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAA BHDCIGGFIGCGIGKJKIKIJKLIKLKILJKKJFHJKKILJJKKLLMHJJKKLLMIJJKLLLJKJMKMNLLIJKLKKLDFLLKAFHDIIIJHKLGGFFJED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.3695912 147 17 1118 60 101M = 1042 -176 TCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAA GDFGGHIJILLFHHMIIMLJKLIJNKKKIMNNKKKKMKMILMJLMMMMLIEIJMLJJIIJIKKLLIKIKIBGHHKJHGEIKFIIHHIGGHBAEFCDEEEE@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GE ERR229776.17531023 163 17 1121 60 101M = 1381 360 ATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAA BEEEDE@EFDEFGFI>GBCBJHFGGIBGFFEJIFJJJJKEFJJJJJKJIHEJKKIEGHJMMKKHGJHFIKJIKKJHJKKKIHJKKLJKHILGMGMHHIEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CGDFG ERR229776.516742 83 17 1152 60 101M = 845 -407 AATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTAAAAAATCTGAAATCCCAAACGCGCCAAT 7?ABDGED>DDDDJE?FB9DDCEA.=<>AD=/AEG6ABA8FD>2CGF@GFBJ?>5*G>59@.<*4JKIB;D*)JJIIBHA:8GC>=E4;H7C>F?GCEDE? X0:i:1 X1:i:0 MD:Z:72C28 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.36576640 83 17 1160 60 101M = 937 -323 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC ADEFFKKIJIIHIIJGJIHIIFKJJINIHJJJMLHGHJLIMHGLJIGEFJKGFDKGCLKLLKMLHKKKKJLJGIKJIKLKJJIGBKAJHIGHHHLHGGHGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.6073289 83 17 1160 60 101M = 857 -403 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC <@AFFKKIJIJHIIJGIIJJHFHKJHNIJKJHBEF@HGKHMLJLJJJLMJKIJGKGHLKLKJLLHKKKJIKJJLKJIKLKJJIGBKAFEIEHGHLHGGHHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.78971137 163 17 1189 60 101M = 1464 375 ATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAAT BBFEFFBCCB@GHHGHHGDHJJJHIGKIHGJLJHJJILLLLILJGKLMIKDFHLKHAE;@HGMGILHFIJIIFGLJJHBCHAGEGIIKIAG>CEMEGEHHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.87728427 99 17 1242 60 101M = 1483 341 AACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAA BHE>G?HFHKGIKKKIIIKKLLJKKKHKCEJJJJEJ?JEBDMJJMABJJIJKLJJJFCDCGDHGCCHEHGHLEEHFGHC;IMIJHGINIIIGIMHIIGGD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BB@ ERR229776.77830097 83 17 1255 60 101M = 1036 -319 GCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAA EEFFIFFIHHGINJAGKIJJGHAIJGKKMKJLKKKINMJMMLKNNNKMMKNMJJLNMMMNKMHJEALKKFJJJLJJIIILKJJHIIIEHIFHHJJJGGFFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IKMJ ERR229776.55719080 147 17 1282 60 101M = 994 -388 CTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGCATTCCCCTAAGCCCG ?EIHGEHF@HCJHEFEIHEGGGHIGHHHKG>BGJDEFDBGJKDCEJKJHJELJJIJIGHF@KKIKILKKHHHIIIKGJJHJHEFDGLJJMJLLKIIJLMLJMJJMNKLLJLKLKLJNNNNKKHKKLJJJHDHGDGJGGLHGHJIHAGHJGIHAGKIHGJII@FFCCCE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G ERR229776.57580585 83 17 1316 60 101M = 1077 -339 GGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTA BEDG?HHKHIJGIKHFHGHKFDIJE?HFHIGJFFFFCCCCCKDEEGFFFFFFFEHDDDFFCJEJLCJIHGLLCLLMKIILK@KKHLKJHIIHKFJHHGHFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.30538656 83 17 1321 60 101M = 1087 -334 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG EEHFDIFIJHIHFFCIFIIIFDGIKJJGGGGDDDDCJDECGEDEFFGECGDDDFGBCACJBGIIEJLCLKMIJKLLBLIILLKKIKHKGKFGIEGDGEFI? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.54641833 147 17 1321 60 101M = 1042 -379 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG FFHGEHEIJDFGBHKIHHGC<4FHIHHFFFF?BDBEI>G>GDCADCDDDI>AAEE@GAAD>FEB@HG8EGHIIIKHAJIHKEFGHEGGEHB;E@BDEEED@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.29727862 163 17 1327 60 35M66S = 1641 363 CCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCGGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTT 7==;A97.8+7HA;IE:88;9EEFH8>;?E####################################################################### X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.82642257 83 17 1336 60 101M = 1081 -355 CAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTC DBEFFGGGIJIKIIIIFFFFFKFHHGHGGGGHD?HEDDFFCKGDGBMJIFJC@MLNMKJLLBMMJMMLLMMJMJLIJLLIILIGIJKJHIIHGHFHGDEGA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.37017046 147 17 1339 60 101M = 1113 -326 TAAACCTGATTTTAAAAAAGTTTGGGGGGATCCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCT :DCCDCJFIJHHF9FFHHMFGCFGGEDEC94#455D@=I?7BADBJJIJBCHMJJDMH?HGDLKJAHEHKA@>B=HDBIGHAEHH8ADDF<8DFEHGEGB@ X0:i:1 X1:i:0 MD:Z:31T69 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.87113255 147 17 1361 60 101M = 1096 -365 TGGGGGGATTCCCCTAAGCCCGCCCCCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTATG FEFFGGHDCHCC;HIF?15;7A:4#FD>JKG@DGMKBFLFKLKAJ@AMEE9BEBB:GFB?CIEHGJA<>DDH=BJEJIBFGJAF:DGDMIIMJJCKLLILLILKHIHKKKIJKHHFDFHKHIGHHFFJGEGFIHBBEF@FEEGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.48996859 99 17 1381 60 98M3S = 1659 345 CGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCT A5FEFEGF?EHHIEIIH8HIIJJIHLJIHGIJHMJJJNA:FAIHGML;0GEDGILGHKHGKHHIKINJKLIJGGFFFF8FFLJJIFEGHLKJGGKMLILLLJKKILKIIILEKHFJJIGEE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ ERR229776.87728427 147 17 1483 60 101M = 1242 -341 TTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCT :=;FCD?1/EECJIGHCF>AAFGCIHKEA=BDAF<:EB>JFJIDBHHCHAD>+#AFDEIE?B@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.15144424 163 17 1542 60 101M = 1799 357 CCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCT BDIECGEFDCEIHBGCGHGGGJEGHBIFHDJIGHJKJIJJKLH?K@JKFJEJIHILMFJMMHB;>IHIIIMIJCKKIFJHGFHJDHGMFIIJG>JFHBDDF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.83025798 147 17 1590 60 101M = 1304 -386 CTTGTGCCCATCTGGTGACCCCTCACCCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC CA;4I?C?9HGCJEBD<08@2J<+=@=DB9CD@ X0:i:1 X1:i:0 MD:Z:26T74 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.29727862 83 17 1641 60 51S50M = 1327 -363 CTTGTGCCCATCTGGTGACCCCTCGCTCAGCCCCCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC ####################################################E==>=55;,C:65/9:=5J=C>FF@=GBJCB?5"D1?L;1=EHG;=BA0 X0:i:1 X1:i:0 XC:i:50 MD:Z:50 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.107364540 99 17 1651 29 101M = 1920 369 GGCACCTTCAGCCACGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAA ?CGGDFL?FHCGFFIAKJIIJGIEHALLJJKGCHGEIEELFIFHMGFGIJDFMFKGIJCMEKHFEAHDF X0:i:1 X1:i:0 MD:Z:14T86 RG:Z:ERR999999 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBF ERR229776.48996859 147 17 1659 60 33S68M = 1381 -345 GACTTCCCCGACAGCCCCCAGCCTCGGCACCTTCAGCCACGGACAGTTCCGCCGGCGTTGCCCACTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCC ##################################G=:?F3CCE>D:8=64'#)'I<=):7>HIB@=A:CE1;:C=JJHC9A:<7=BCFHCL@LHEHIEHA@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.69874320 163 17 1704 60 81M20S = 1920 309 TCTCTACCAGAAGTGCCCTTCCCTCCTCACCTTACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCCGGCACAAGCCCAACCTGCA 74J?@C:D@-=C;696/*=;DD8+@*@7C94='04*65:A@860;+9H##################### X0:i:1 X1:i:0 XC:i:81 MD:Z:32G48 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.51562629 147 17 1727 60 101M = 1445 -382 TCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTG ADDFD?GHHEBGIGIHIJHHHHGGHGFEGHFJB;2CB?FADDEAJDDFC@8ABCE?A@BCACCB@H@<AEGG@HEG;ACBGCHFFAFF/?GFJLHILKLHIGGIJM:CECFEIHLBFIDJEHEHILAHB5CFG@FGGLHHHGI3?FFILIHHMHGGKC6C X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GAA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.2494821 99 17 1749 60 101M = 2024 375 AAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGT AHHGFFFLHHGIIHKKHHJKLJKLKJJJJLLMJJJJMJCLJJJNFJLMKKMMNLMKLNMMLMIMHKJHJGG@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@FC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.15144424 83 17 1799 60 101M = 1542 -357 CCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCATG @BGGGGB8D@HEHKEJFGGGACGCGKFGGF?EGCCCCDDCGEEFEIGFHDIFJEGGFJDFEBHCEFGEGJKE>LLLKJKII@KKLKKAIHFIHFHHEGFHB X0:i:1 X1:i:0 MD:Z:70A27G2 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@Z\V ERR229776.97978507 163 17 1893 60 101M = 2135 342 TGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGT BEFCHHGIEFJDFKHGBGCFF7CAD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.107364540 147 17 1920 29 101M = 1651 -369 AGTGCCTTCTGCTTGCCTGCGGCTTTGACAAGAACCCGCTTCTGGTTATACATAAGACAGCCAGAGTAGGTAGTTGCCCAGGGTGGCACACTACGTTGCTG <@DE96DJHGG>8CG@:?4$=@*IBB@41AEC<=3+#(B<@6F=287JIG?C8(A@BCIH>MLJFH?C;CJIFGCGDIBIJHDCJCEFFHHIHD?ALEC5CHMD38CECLGCE?45HLCE;BEGFHGJ<=C? X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.43533499 83 17 1932 60 101M = 1693 -339 TTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCC 2D>ADFGGIIHFIKILIFLDB51FCBHGGCKJILFIKKJKKJMIHJMLKJMLMJHLIGIMJMKJGJHGKKIJHFIIFLDHG@HIFIGGGH?KCEGHGGF?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.22929983 83 17 1950 60 101M = 1693 -357 AGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAA HEA>CFFGIHKIKIGMKLKJIFKKMEIKLJHKNKMKKNMMLNKNKMJCLMMMJJMMLJKMLHIAKMJLLJKLKMJLJILJJKHHLLKJIIFKGHHHGFFFB X0:i:1 X1:i:0 MD:Z:91G9 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ADB ERR229776.66105707 83 17 1971 60 101M = 1746 -325 ATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGA EFCIGFCMICINIMIGJIKKNBJKIHIKMJJKKLJIFINLJKCKMKLMKJJGMJMIGKJHFHIMMLKJIIMLKJIIKKJIIKKKKHHDIIGIHLFGKF:FB X0:i:1 X1:i:0 MD:Z:70G30 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.105154648 163 17 1981 60 101M = 2189 308 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGC @DCE:EEFD<=H?>>?FF==CCB@1:C=FFGHG;<=?HKICHBC?4AFEE:HEC5AJ3B;H?A>6BCEB85 X0:i:1 X1:i:0 MD:Z:60G40 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.52172354 163 17 1982 60 79M22S = 2196 314 AGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAAGAACAGGAGCGACCGCACAGGCT A@?:E>31<61E<;88BG,%/C8/4BAG4;BA1AG92D;D?C9<=)?>;C?BDF+9D+0>>0;DGJG####################### X0:i:1 X1:i:0 XC:i:79 MD:Z:59G18C0 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.39805220 163 17 2022 60 82M19S = 2315 385 CAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGAT @94EAE@J>:3GGEGCGD9=ECACGGHHHE;HHB?DFC1E:AA@AJJE=@C6=43>@CI?8DBC#################### X0:i:1 X1:i:0 XC:i:82 MD:Z:19G62 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.57143597 163 17 2024 60 101M = 2298 374 GTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATAT @DAECIBEC@AGHEICGGIHJHGIEHAGHEDGICFLHILJCJ8FDE>KDD3;C?CJEDHFGEGFCF=F<>>EBIE@DECD?>DB9BECBHCJDADD;AE@;>C>HLEFCDH>IILJ@G6IJGG:AEJACCEEB@ X0:i:1 X1:i:0 MD:Z:17G83 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.11251161 163 17 2065 60 101M = 2333 368 GGAGCGACCGCGCAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGC @3B"2=<"5?9=JGBBB'=:@;DFC=?698AFCD4;74C@EBD7IBFHH8AD@G+-3HGHFHF>IIKJKIHKBKBLJLLLLJLLJKJJJKJJCHJKJLHMMBLHJJIGIJGI>HFCFGJKEHGFHIFMIJMIDMIIMIHGHADFFIHKIGHEDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.18301321 163 17 2092 60 101M = 2301 307 GTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCT AFEECE789<',AD@GF@BG?>H<4F7GBIE=@>FCF;=;CEBFE>D=A=AAJGHKH;DDFKHG?C02BAIHG@@FEAA3=6 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.97978507 83 17 2135 60 101M = 1893 -342 TCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGG E=FGGHIGKINJBIJIJGMIJFMIJHIHJHHIGJLHJJIILFNNNLMLKLJKJGMMMLKKMLMKKJLLLLLJLLLJKKJILLKKJLKJJIEGGGHHHGHEB X0:i:1 X1:i:0 MD:Z:85G15 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG ERR229776.15256528 147 17 2147 60 2S99M = 1898 -347 AGCGATTGTCACAGGCACTGCTGCTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATC ###E?E<9G=8IMIIFGED<9;(BABBB;8;99?ABIGDCHJD?<:;C7FBEE3EBHDG9@CCKGHH@??D@;HFG>1EEF=BCDAG9631,D9DE@7 X0:i:1 X1:i:0 XC:i:99 MD:Z:20A52G25 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.75821297 145 17 2155 37 101M * 0 0 ACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATG EFKFHHIIJIIH@IKGIJHHHFLLLJFGJKHJHEIIMJJKMLNKKIKKMJGELKLJKGHGLLKIJLKJKIJIKKIHHJFJJHHHHHGFGH<;DEFEIEEG@ X0:i:1 X1:i:0 MD:Z:65G35 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.105154648 83 17 2189 60 101M = 1981 -308 CCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATG ?BEHFGKILIHGFFGDFGEGFBHEGKHNLFJNLKKKLILKKIKKKLIFJCKJJJJLJKJJMLMJIIJJICLLJJIIJIIEHJGGJHIFHIIHDHFFFEFH? X0:i:1 X1:i:0 MD:Z:31G69 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.52172354 83 17 2196 60 101M = 1982 -314 GAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTT EHCBDDB?7=E=DBAKCDGLHHEIMICHKJHAKKKK>CDJIJIKMGFJKIFFJMLMHIIEMJKMDHIJKJKJJJIIJKIJJJHJHFHGFIJGADHICGHJIJKDIIFIJCGEDGBD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F ERR229776.59500924 99 17 2276 60 101M = 2490 314 GCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAAT &HIEGHLHGHFIHEKIHKJLJILJJLLKIIMJLLLJMJIHMKKJJMGFJJLCLIJNJKJLJGHGJ>G@@GJGHIHKHJJFIFKIKIKGIJIIIMHAEFGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.57143597 83 17 2298 60 101M = 2024 -374 CACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACA ?EDFHFHFHHHEFJJFIHDEJFHHMEIF@KOJJJNJKMJMKL?JNMKLNKLMLMJJMJMMKJLCBLJILJLJLKIIKJII@JJF?JIFHEFKFJHIGGGFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.18301321 83 17 2301 60 2S99M = 2092 -307 ACCTGTAATCCCAGCCCTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGCCCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAA ###GAB7.BC><:*5'=GG@A:?H@A8,@B77FE-EIEEEHBDBKJDH=IACICBGGLLJHH'%/HLJCHICICFADHA?E?>:B?I:FG=EI:@@=ADC? X0:i:1 X1:i:0 XC:i:99 MD:Z:13A47A37 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ED ERR229776.39805220 83 17 2315 60 8S93M = 2022 -385 TCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACA #########DFBIFEJB?%?I@FFIMFFGFFFD;DLMJEJ>8FGMHGHBMKHFM=/GCJFJKEKJCFJD8JAHHIJJIIIDII@AEJFGHBGHHHHFEHC? X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.12020490 147 17 2330 60 101M = 2089 -341 CTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGT EFKFGLHIEHGFHIIDDHHCIAJGBBHDB;=+EB@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.11251161 83 17 2333 60 101M = 2065 -368 GGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGT BA,>9DHC@BEKKIKCAAGKFEGIIHDCJHEG?IIFKJDEFFIMHKIDHDFFJJJIIICEEHJJIJJIJECIKJJILEI?FHFDGEEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.80729707 99 17 2417 29 101M = 2698 358 TAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGA :EBE?HH>CECHH;>?IDEFLDGNIJIGHG@B?AGF@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.101859832 99 17 2474 60 101M = 2762 388 AGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAG ?ECGDLGFKGCKHGKKIGKGHGIIIKJEILJKLJFJ@EHGH:CHJL?HJHIJHMLLIJIEFJKIIE=HB>HGJHJIBEH>GGJHJHHFMG;H?FCHB6>CA X0:i:1 X1:i:0 MD:Z:90A10 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229776.59500924 147 17 2490 60 101M = 2276 -314 AGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAA IEFKEGJJIMIIDJJIJGJHMHHIHIGHI?HHJLHJJJLKJMKGJMKJI?DJJKJJMKLJIIKHJFCGIFIFJ;KIIIHKJGGJIHHIGGCB@FCIEEEEB X0:i:1 X1:i:0 MD:Z:74A26 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEC ERR229776.5983641 147 17 2506 60 101M = 2267 -339 TGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAG GDGGKHHJGGEIKAGHHKIKHKJHKMKEGNJJ?;LIKJJCJJNGJKLHKHCJHFFEK>GJJJJKFIJKIJHJIIIHHIHKJGGHGFHGGGBBEFCEFEEI@ X0:i:1 X1:i:0 MD:Z:58A42 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.52727770 163 17 2538 60 101M = 2848 395 CCGGAGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGCAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTT @0=>12?7?C;8I=0;9>#AH@ECA9=9=0().D=:;CKBE'450120:7+@C=E4C6E@CE5ACFI@D<@>9G=?;?E*=3HEKKJJCHKKHFHGJKLIILLGJLLLJJMMJJIMMMJJMHKKEEJGKLJKMLMKJJILKGLHJKJIIMIIIMFFIGIGGKFGE X0:i:1 X1:i:0 MD:Z:17A83 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.18618553 163 17 2570 60 101M = 2828 358 GAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCT @>DGC8=FEC>CGDIEHCACFGFKKAFHKJBDDCJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E ERR229776.83543817 99 17 2577 60 77M24S = 2821 288 AGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTC 4::A:>A>G8)>F<>ADDHDCGAJ<=JB,*EB797,>HHL@C95=/:EC=@@FC>GEJHC=479788BI96F0EKK######################### X0:i:1 X1:i:0 XC:i:77 MD:Z:77 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.66162627 99 17 2602 60 101M = 2766 264 AATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCT ?DFGEHGFHIHGJEKKGGJJLJKKJLLIIKMIFHMJJIIJLLKJJIJKHJKMKFAJLJKLJKGBHJIFKGHHLHIJMIIGF>BCGJGKDCJIJGGFKFIEH X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J ERR229776.36854728 99 17 2628 60 99M2S = 2910 357 CATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGG 4GFEJG@EKG=@.BEGJ+AHFCFCGLGGD/E9CGADGFH?GDKGLFIAHDJ@BHGLEFDGEE=DDGIBFB### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@@ ERR229776.80729707 147 17 2698 29 23S78M = 2417 -358 TGCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTATGATTCAGCTGAGGGGTGCCACTCTTACCATCTAATCTGTGCGCTTATTTACTCTGCTTTAGT ########################HI<4*16J>9**D?/?:9**HC)F3A'6B3F/;1.(((>/2&-5=*;,3HA<':0+('/(;/*7.(7%;'.2C@481 XC:i:78 MD:Z:15G3G15C21C7C12 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.94440410 147 17 2716 60 101M = 2419 -397 TGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGAC DEFJHGD>7E>ADGG@:9HJBIEADHGGGIHJJFGA>A?99DEKGFCC=4<%DGG;@BCCEDDF### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.45483038 99 17 2750 60 101M = 3055 353 TGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTC BFHGGFFLHHGIIJKLKKJKLJJIHIKKMLLLLLMFEKMMNLMJLLJJJKMIFCFLILKLLKMLNLICHBEJ3AFAEEKCBCDGFIF;?=CCHFFEEC83; X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.78014576 99 17 2757 60 91M10S = 2948 291 TTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTC BFGGGHGFKHIIIHIJFKHIKJLILLKLJKKMLMJLFJLJJJLNMMMMLMMKLMKMLKLJBJJFGCGFFECGHFB@HFFF/7@67?9E@F########### X0:i:1 X1:i:0 XC:i:91 MD:Z:91 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.101859832 147 17 2762 60 101M = 2474 -388 TCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCA <8=DBIGIHJGIDJIMHICFA?BGEFAG9FEGAAJ@CC?@DCFHAJ>>811?C;85FEHCBHA>@K8EE=3@<@EHB=;HI>FF?EB@FF=C5CBA@ X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.66162627 147 17 2766 60 101M = 2602 -264 CTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGT EHGCA-@LEEDGHEFLEMHB?B?@FGEIDG?CA?FC>ACD1??@;AEAGCGGAAJKGFHK=IEB?LGCEFFHDCG#:3?EBFBGDF X0:i:1 X1:i:0 MD:Z:90T10 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.44852854 83 17 2817 60 101M = 2547 -370 GGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGA BCC?6ABEHFILIIJJGGG;IGIHMIHIHF?EH?HKHLKLKKMMLNMMJKKMMKMKLKKNLJKKKLMMLIKJLBKLJJLLLKBIIKJFKIIHHHIHKEEFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.83543817 147 17 2821 60 56S45M = 2577 -288 TCTGCTTTGGTGAGGAAGAGGCCCCGGGTCCATGAAGGGGCCTTTCAGAGACGGGGGCCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGG #########################################################7,,/?4:@2;'B6#'01'8,2'4&8.;H29?@:+&'-13CH;-1 X0:i:1 X1:i:0 XC:i:45 MD:Z:0A44 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.18618553 83 17 2828 60 101M = 2570 -358 AGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAG #B7@??990GHIIMFDEICAGH?FHCD<+@FEEHHIIIJILKKLKJKLNLJKKKMLMMJKIGBKIJJMMKK>GJLKJIKLLIHEJKJJIKEHGHE@EFDK? X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.91229453 99 17 2831 60 101M = 3084 353 AGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTC ?CGEEF?HBGFIGFKJJABI@JIIIKKJJLKJKLLABEHLJLLMKKILJJJJFKKHGFLI=DD?BGFEG>@BBFIJKIKGIHJIG@HHHFKGEF:E7 X0:i:1 X1:i:0 XC:i:86 MD:Z:86 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.7004516 163 17 2878 60 101M = 3107 329 ATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTG @EEFECDFD;:JG0C=?D;AGJ?GGGJEI<=JHHHHJKIKE>CFIKLGGE?HIH6?CAF>GBKBA9GIGB?EDFE@IHGFGHIGEFFJG:@FIC@EDB?6B X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.36854728 147 17 2910 60 25S76M = 2628 -357 GGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCA ##########################HHKC9,>ABC?;DBGAH=8;;IEE<>2?HB@C>HCF7<;2G79===)C@5&=*B@86FEEHA@B9:<797DB3;@ X0:i:1 X1:i:0 XC:i:76 MD:Z:76 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.28172972 163 17 2918 60 101M = 3194 376 GTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGGCCAGCAGCACCCACAGCAGCCA BFECEDAFC@CGJH?GIIGGHIJIIGJHHD;A;@=D@9BE>:D=BHI9;;A"99>><@>BCEEE=CFEFIBAC# X0:i:1 X1:i:0 MD:Z:78T22 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.78014576 147 17 2948 60 101M = 2757 -291 GCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGT C@AB=GIC>BDHFFG@@??HHFHGEEIGHHHFBCFFIHHDJJEFMLHJKFEFHILEF>IHGGIIHJIHHI?EKIIHJJEJJHEJIDJHHIB@ED@EFEIDB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.19870548 163 17 2964 60 101M = 3254 390 CACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCA ADDECGIGHJHBFH:F=:<9D??FIKJIGJHCHLGIHIEABDE@CGDDFFAFA?CDE@E9B?6>4B@@FAA6E6@5*>1=B>DB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.91036639 147 17 2967 60 101M = 2776 -291 GGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGAT 53AFE?BAHGJIHIBCCEDIGIF=GGGGHKCFKF@F=?CGLJGBKIIKGG?:IJJJJKLJKLKJLKKKIKHB@HICHBHKHFEHGFJHGFBCFE@CEIFEB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.11173812 99 17 3034 60 101M = 3333 399 AGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATTTGTCACAGCAGGTAAGACTCTGCTTTCTGG ?CFKBHGHEHFGHEIGDHHILKLLLMIIKLJJKIJIKILMMM>JIMIHIMJFCDJLG0ADIHIGCGDEHHHEHIIKHKHGJIG8GKHKGNIMIIKGDFCEA X0:i:1 X1:i:0 MD:Z:70C30 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GF ERR229776.45483038 147 17 3055 60 52S49M = 2750 -353 GCCCCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCAT #####################################################A54-7=90;?5::24>EAB?DH@DE X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FJ ERR229776.59323675 163 17 3154 60 101M = 3389 335 TGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTG @B?ECD9@8@GCII88GHF<9:FIIILLLLHFJEHHJJHIJGKJGI?@BJJJJKDB>DKDJC<@EEBHFLGF?EIAGEHCCD@2ABEACFHDCC#9@?###### X0:i:1 X1:i:0 XC:i:96 MD:Z:91T3T0 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.28172972 83 17 3194 60 101M = 2918 -376 TTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCA BDFCHIEIJGKDHIJHIJIMHGG?IHIHJHKHJJGCGFKBMKMKJJLKLJJIIJFJMMMKMMMLMKFHLMKJJLLJIKIIKGDKLIKKIGHHKFGLDIHFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ABA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D ERR229776.453972 81 17 3215 37 2S99M * 0 0 AGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT ###>6FEBCCE@HGDIIHDG?GEIICHHF@FBBIGHDFFF1JMLLLJCIMLIHFLIHJIJFGE?KLJMMHCDKMLLKJLIIJEB@KJKIEGIGHFHBFEE? X0:i:1 X1:i:0 XC:i:99 MD:Z:99 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.41226651 99 17 3242 60 101M = 3478 336 TCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAA BFEEGHHFGKGIIEKJKGJHIJIIIIIIEIJKJKJIMKLLMJJJKMMGKDCIJLKLGIJFIGHCBFDHFEIHBEBCKHHDHHI?GIJJGNIHHJGDGEGDD X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IIK ERR229776.19870548 83 17 3254 60 101M = 2964 -390 GGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGC DEFIFHBEIIIDHFIGKHGIKCHIGKKOJILHMJKNHKGJIEKIMJMJDDJIJGAKKLKKLKKMKJJLLLCIKJIIJIJJJJHDEJIIIIGKHLHFGGEFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CCA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.43420834 99 17 3270 60 101M = 3494 324 TGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGGGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGGGGCGCATGCCT ?ECHGGHFKIBJHJFGHKBJJIJKJMHKIKJMLLMIJKMKNKKJLI%@GMKHILH?EEHFAJJMMMDFBDIJJJGHGJDDHLDCG;HDA#77=FIJFJIJ=JJIG;EJEFBIKKJFE:GFD8/9:*E@EE3%DJ;D2BDD@ X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:IH@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.94803111 163 17 3384 60 101M = 3606 322 CTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGA BIEECCDHEBEGIBIGIGGHJIJHKIJKIHGLIJLJKKKLKKJKKJBIJIEJKJKKKIMJKHLEFIF@HFGDKGHIFLHHIHIHMIGBGJHGJIJHHGEFG X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.91011602 83 17 3387 60 101M = 3102 -385 GGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTC DDFFKHHFIMIHIJKGLIHIIHKIGJIDHIJKIJKNLLLNLKCKNKMJNKKMMJKKHNMJLIFAJJHIHIIHGLKIGJKKLIKKKJIHILGKFHHLEFDGB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.59323675 83 17 3389 60 101M = 3154 -335 GAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTG A5IGFFHGIIIJKINGEGIGI;KHE?1IHHJJKMJJHMKJBKNKMJMHGIMJIJLKJHKIE?GFFJKJEFEHKEIKIEGIFHC;AFHIGL@HHLGIGHDH? X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.5896825 83 17 3415 60 101M = 3144 -371 ACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCAT @>>ADEB1CA>FB277FJIFJ;=B18+/A098D=55?==:<>(;0=7BBH@>BEHFCBBC99?JA6@G7.A;?:7:AJGJJJJIJJIGIIGGIFHGEEFE? X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A ERR229776.43002343 163 17 3466 29 43M58S = 3687 321 CCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATAACACCATTTTGGCTTCAGAATTCATATCCTCCTGCAAGGATATATACGCGAGAAATTA 58=>BB1BB659IJHIGHHF:IFBBBHBFAG?G@HFCF;AGFDG>:AECFEEGAA X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C ERR229776.43420834 147 17 3494 60 101M = 3270 -324 AAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAAC A9>D?@DFHHFFG9?577GHGD;IIGHGIGFKFFGDEBGACABDIB>I?G?HGKICIA9F<=>9>IGIIHJ@HIKCDDHGG<>GGCGCDJBBEFCFFEC<@ X0:i:1 X1:i:0 MD:Z:93G7 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:G@CICDGHJIEDB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BC@CCB@@@ ERR229776.98041640 147 17 3494 60 46S55M = 3175 -373 CCCGCCCCGCCACCCCAGCCTGGGCAACAGGGTAAGCCTCCGTCTAAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGA ###############################################?DHGJJJHE?HD9;D;0@HD?:J7>:5>8GIIJHFGHJIHIIIINIGMIIGHFDED X0:i:1 X1:i:0 MD:Z:57G43 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.98929975 83 17 3553 60 101M = 3302 -351 TACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCT A?>E?FIIFFJKKIFNGKIKJHIHIIEHJHLHDDDCCKJCGJJJKJJJJFFBLJKIFMKMJJJLJJJFLKIJIJJJJK@ILLIILIIFGKIKI?GHGKGEB X0:i:1 X1:i:0 MD:Z:34G66 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.105205152 99 17 3562 60 93M8S = 3856 394 AATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTT ?D>?9HF>@ECDFDCDF;HBDCIID9797+7.7B>6=HL######### X0:i:1 X1:i:0 XC:i:93 MD:Z:25G67 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.30258628 163 17 3583 60 101M = 3859 349 AGAAAAAAAAACATATATATACGCAAAACAGTATCCTACTGTGTGTGTCGTTTGTTGTGGTTTCTACAGCTGTCCGTGTGATAATAATTCCTCTAGTTCAA @@GCHH;6=>ECF=G4D==2BC*:=)6)'/-/4107;+4+@=E7,CBC:;C;BLB?HDGGB X0:i:1 X1:i:0 MD:Z:4G22C31T4G14T21 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:OOVRWWJELKO@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG ERR229776.15284212 99 17 3585 60 88M13S = 3809 324 AAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAAT ?DEDDFFEIECHI;HHHAHI>HGLLGKIJGHFHCJIHEAGF:FJJDC8GIDFJBCFBHDGGH5GCFCBC=:AF/1826-7FJEIJHI############## X0:i:1 X1:i:0 XC:i:88 MD:Z:2G85 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:MRSRRTRPQ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.15906182 163 17 3598 60 101M = 3862 364 TATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTA BFEEEE@EKCDGA@>G@D?HJIIC;?=CD@JK?#;BJJ5DECBIABFDGHHCGFE?DJDGJGKDGI5BEIKHFFIKD-BHEFEGMGIIKGIJJIJGJGJDJFJ?FMMKHNKIKKNNNLDMKLNLKKKLMCKKKNKKJLKJKKMKLKKMJMJMKKKKJLLIIIJJHJJKIHHGHJIGFFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.15603458 163 17 3626 60 101M = 3846 320 TGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTG @EADDC9A@B@GH@GBCFB>>3CD?=;E@9>H;C;IJBIIIIIJIJHILHCBAF;=GI@BJDJE>>CFHKHIINE:BHIGH4E?EHJGG>AFMIFIEHAJ4 X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.80842527 99 17 3639 60 101M = 3844 305 GTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTC AGEFGHHG?JEIHJLJIKK@IJJJIJJMJJMJKMKMMMJMKKMKNNKKLJKLMKKLKLLKMKNLLKKKNLKKMKJJLLLLLJLILIPLJKILJIIGHFEJD X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.84503264 163 17 3670 60 101M = 3903 331 TTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATC AEFCIEFFEB,CEHH?*;6936?956.-2%7)=C@3?BB.6C891FDGFJ?==>D@A:/DEB5@4BDG@D@ X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.78993145 147 17 3760 60 101M = 3530 -330 AACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCG 1@DGHHHFIJE@:CKDGIJIFHJBFBFGIHJJEFCHGEKEIIHGJGFAIKDJJMLJJIILDKIKIKIHHJEBBAIHJJE?HHIGGCGHHGABEHDEGEH9A X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.102280357 83 17 3772 60 101M = 3516 -356 ACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTG ;EGFFHIFGIKIKGJIHGHJIDGIJHIJHIGGGHG>HLJJJNIJKKJMJNKLMKJLLJJJDCKKLKJAIGLJIJGIJJLKJLICJGJAIIIHKHHHIGHHB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.60297548 147 17 3785 60 101M = 3736 -149 GTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCT @GFFFGJIJGIIHHKHJHHIHF@FIHIJLIHIFFJHJAGAIIHDGFDGAIEGHIAIKHIJIJKKIJKGKJD@IIAJKKEKJGDDJCGEE:,BJIGFGEFHFEBALJGJ?K4E;KILICFJELIFKJB>AHAF@HFGEGGGC? X0:i:1 X1:i:0 MD:Z:90A10 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.105205152 147 17 3856 60 101M = 3562 -394 TCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTC #BE=GGHILIIHKHHJGJHJDHEKD;+EBF?C>FFJ?E?DCIFEIGB>=HGBDILKGIFB>FI=9*=<><'?;C69?8,6?DD253-72,D9>: X0:i:1 X1:i:0 MD:Z:80A20 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.30258628 83 17 3859 60 27S74M = 3583 -349 TCGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATAT ############################FLLJHF-.LGLKHKKHCIBLHBHDB?@@;7IH=9>7/5HIE+A@EHICFFIGIJ@AGI?>KHAGEFGHE:DE7 X0:i:1 X1:i:0 XC:i:74 MD:Z:74 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.15906182 83 17 3862 60 101M = 3598 -364 TTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGG FEFFGGJHCKHHKKGHILFE@:EBCFIIHLEHHIMHEEIFBEGJJJKIIBAIGJMMLMMJMIIJIJKJJJMGLAKAKFFEJIDGHIHCJK@GJJHJGGHEB X0:i:1 X1:i:0 MD:Z:74A26 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ ERR229776.104583040 99 17 3884 37 84M17S = 4097 298 CTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTA ?HFEEHFHBC7EGAHIHCHFDHL?HJ=FI48C>KFJL=EKCCJJJALKHJLJLLIIHJFKHIIGGKJHCG?EFBHIGDCF>F@CCDFEGEGFF@ X0:i:1 X1:i:0 MD:Z:39A61 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B ERR229776.84503264 83 17 3903 60 2S99M = 3670 -331 GCCCCTGCTACCCTCCTTCTTAGGGCTGATATTCCGCGCCCCTGCTACCCTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCT ###?DDA5-;91@B:HBJ<:89-=F65868-%4C9E5-=>9C+9C9H;AFC7GEBCCJJILKJHHAIHELLIJJD=C>IFEIIJIJHLEEGEB X0:i:1 X1:i:0 XC:i:99 MD:Z:0A8A23A3A8A52 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ bcftools-1.21/test/mpileup/mpileup.5.out000066400000000000000000003522451467060157400202760ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 100 . C <*> 0 . DP=18;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,672,27586,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,189:9:0:9,0:0,0:9,0 0,9,118:3:0:2,0:1,0:3,0 0,15,134:5:0:5,0:0,0:5,0 17 101 . C <*> 0 . DP=18;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,630,24730,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,182:9:0:9,0:0,0:9,0 0,9,108:3:0:2,0:1,0:3,0 0,15,132:5:0:5,0:0,0:5,0 17 102 . C <*> 0 . DP=18;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,676,27812,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,188:9:0:9,0:0,0:9,0 0,9,121:3:0:2,0:1,0:3,0 0,15,139:5:0:5,0:0,0:5,0 17 103 . T C,<*> 0 . DP=18;ADF=15,1,0;ADR=1,0,0;AD=16,1,0;I16=15,1,1,0,668,28542,6,36,929,54841,29,841,323,7035,6,36;QS=2.98256,0.0174419,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64924;SCBZ=4;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,17,184,24,187,185:9:0:8,1,0:0,0,0:8,1,0 0,9,118,9,118,118:3:0:2,0,0:1,0,0:3,0,0 0,15,147,15,147,147:5:0:5,0,0:0,0,0:5,0,0 17 104 . G C,<*> 0 . DP=18;ADF=15,1,0;ADR=1,0,0;AD=16,1,0;I16=15,1,1,0,601,24163,3,9,929,54841,29,841,320,6884,7,49;QS=2.98726,0.0127389,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64309;SCBZ=4;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,173,24,176,173:9:0:8,1,0:0,0,0:8,1,0 0,9,101,9,101,101:3:0:2,0,0:1,0,0:3,0,0 0,15,133,15,133,133:5:0:5,0,0:0,0,0:5,0,0 17 105 . G <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,603,22351,0,0,1018,59282,0,0,325,6815,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,171:10:0:10,0:0,0:10,0 0,9,106:3:0:2,0:1,0:3,0 0,15,125:5:0:5,0:0,0:5,0 17 106 . G <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,636,25058,0,0,1018,59282,0,0,324,6718,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,190:10:0:10,0:0,0:10,0 0,9,92:3:0:2,0:1,0:3,0 0,15,124:5:0:5,0:0,0:5,0 17 107 . C <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,686,27952,0,0,1018,59282,0,0,323,6643,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,192:10:0:10,0:0,0:10,0 0,9,119:3:0:2,0:1,0:3,0 0,15,136:5:0:5,0:0,0:5,0 17 108 . C <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,681,27429,0,0,1018,59282,0,0,322,6590,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,190:10:0:10,0:0,0:10,0 0,9,119:3:0:2,0:1,0:3,0 0,15,135:5:0:5,0:0,0:5,0 17 109 . T C,<*> 0 . DP=19;ADF=16,1,0;ADR=1,0,0;AD=17,1,0;I16=16,1,1,0,716,30648,2,4,989,58441,29,841,309,6415,12,144;QS=2.98922,0.0107817,0;SGB=-0.556633;RPBZ=-0.674966;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.6661;SCBZ=3;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,20,191,27,194,191:10:0:9,1,0:0,0,0:9,1,0 0,9,120,9,120,120:3:0:2,0,0:1,0,0:3,0,0 0,15,150,15,150,150:5:0:5,0,0:0,0,0:5,0,0 17 110 . G <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,688,28036,0,0,1018,59282,0,0,320,6550,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,194:10:0:10,0:0,0:10,0 0,9,113:3:0:2,0:1,0:3,0 0,15,136:5:0:5,0:0,0:5,0 17 111 . G <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,573,21453,0,0,1018,59282,0,0,318,6514,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,167:10:0:10,0:0,0:10,0 0,9,95:3:0:2,0:1,0:3,0 0,15,119:5:0:5,0:0,0:5,0 17 112 . C G,<*> 0 . DP=19;ADF=16,1,0;ADR=1,0,0;AD=17,1,0;I16=16,1,1,0,657,26565,2,4,989,58441,29,841,301,6277,15,225;QS=2.98907,0.010929,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65292;SCBZ=3;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,20,187,27,190,187:10:0:9,1,0:0,0,0:9,1,0 0,9,103,9,103,103:3:0:2,0,0:1,0,0:3,0,0 0,15,135,15,135,135:5:0:5,0,0:0,0,0:5,0,0 17 113 . A G,<*> 0 . DP=19;ADF=16,1,0;ADR=1,0,0;AD=17,1,0;I16=16,1,1,0,635,25055,4,16,989,58441,29,841,297,6207,16,256;QS=2.98817,0.0118343,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65205;SCBZ=3;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,20,172,27,175,172:10:0:9,1,0:0,0,0:9,1,0 0,9,102,9,102,102:3:0:2,0,0:1,0,0:3,0,0 0,15,139,15,139,139:5:0:5,0,0:0,0,0:5,0,0 17 114 . C <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,660,25876,0,0,1018,59282,0,0,310,6446,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,181:10:0:10,0:0,0:10,0 0,9,113:3:0:2,0:1,0:3,0 0,15,133:5:0:5,0:0,0:5,0 17 115 . C A,<*> 0 . DP=21;ADF=17,1,0;ADR=2,0,0;AD=19,1,0;I16=17,2,1,0,688,27426,12,144,1078,62882,29,841,283,5827,25,625;QS=2.88785,0.11215,0;SGB=-0.556633;RPBZ=0.260329;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.47798;SCBZ=-0.418446;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,189,30,189,189:10:0:10,0,0:0,0,0:10,0,0 3,0,86,9,89,93:3:0:1,1,0:1,0,0:2,1,0 0,21,153,21,153,153:7:0:6,0,0:1,0,0:7,0,0 17 116 . A C,<*> 0 . DP=21;ADF=17,1,0;ADR=2,0,0;AD=19,1,0;I16=17,2,1,0,705,27791,2,4,1078,62882,29,841,287,6073,19,361;QS=2.98873,0.0112676,0;SGB=-0.556633;RPBZ=0.0867763;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.65814;SCBZ=2.65016;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,20,179,27,182,179:10:0:9,1,0:0,0,0:9,1,0 0,9,102,9,102,102:3:0:2,0,0:1,0,0:3,0,0 0,21,175,21,175,175:7:0:6,0,0:1,0,0:7,0,0 17 117 . G <*> 0 . DP=21;ADF=18,0;ADR=2,0;AD=20,0;I16=18,2,0,0,715,28045,0,0,1107,63723,0,0,304,6444,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,185:10:0:10,0:0,0:10,0 0,9,97:3:0:2,0:1,0:3,0 0,21,177:7:0:6,0:1,0:7,0 17 118 . G <*> 0 . DP=20;ADF=17,0;ADR=2,0;AD=19,0;I16=17,2,0,0,620,23470,0,0,1047,60123,0,0,303,6481,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,175:9:0:9,0:0,0:9,0 0,9,65:3:0:2,0:1,0:3,0 0,21,162:7:0:6,0:1,0:7,0 17 119 . G <*> 0 . DP=19;ADF=16,0;ADR=2,0;AD=18,0;I16=16,2,0,0,619,23459,0,0,987,56523,0,0,301,6493,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,176:9:0:9,0:0,0:9,0 0,6,76:2:0:1,0:1,0:2,0 0,21,160:7:0:6,0:1,0:7,0 17 120 . A G,<*> 0 . DP=19;ADF=15,1,0;ADR=2,0,0;AD=17,1,0;I16=15,2,1,0,646,25392,4,16,958,55682,29,841,277,5999,23,529;QS=2.9873,0.0126984,0;SGB=-0.556633;RPBZ=0.28942;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.6486;SCBZ=3;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,171,24,174,171:9:0:8,1,0:0,0,0:8,1,0 0,6,88,6,88,88:2:0:1,0,0:1,0,0:2,0,0 0,21,171,21,171,171:7:0:6,0,0:1,0,0:7,0,0 17 121 . G <*> 0 . DP=19;ADF=16,0;ADR=2,0;AD=18,0;I16=16,2,0,0,650,25148,0,0,987,56523,0,0,298,6534,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,181:9:0:9,0:0,0:9,0 0,6,84:2:0:1,0:1,0:2,0 0,21,168:7:0:6,0:1,0:7,0 17 122 . C <*> 0 . DP=20;ADF=17,0;ADR=2,0;AD=19,0;I16=17,2,0,0,696,27784,0,0,1047,60123,0,0,296,6560,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,180:9:0:9,0:0,0:9,0 0,9,107:3:0:2,0:1,0:3,0 0,21,178:7:0:6,0:1,0:7,0 17 123 . T <*> 0 . DP=18;ADF=15,0;ADR=2,0;AD=17,0;I16=15,2,0,0,647,26145,0,0,927,52923,0,0,296,6554,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,170:8:0:8,0:0,0:8,0 0,9,123:3:0:2,0:1,0:3,0 0,18,166:6:0:5,0:1,0:6,0 17 124 . T <*> 0 . DP=19;ADF=16,0;ADR=2,0;AD=18,0;I16=16,2,0,0,606,22002,0,0,987,56523,0,0,296,6564,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,154:9:0:9,0:0,0:9,0 0,9,114:3:0:2,0:1,0:3,0 0,18,154:6:0:5,0:1,0:6,0 17 125 . A T,<*> 0 . DP=18;ADF=14,1,0;ADR=2,0,0;AD=16,1,0;I16=14,2,1,0,589,22565,4,16,898,52082,29,841,272,5916,25,625;QS=2.98444,0.0155642,0;SGB=-0.556633;RPBZ=1.02125;MQBZ=-2.16025;MQSBZ=-1.23956;BQBZ=-1.64106;SCBZ=2.91548;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,149,21,152,149:8:0:7,1,0:0,0,0:7,1,0 0,9,114,9,114,114:3:0:2,0,0:1,0,0:3,0,0 0,18,162,18,162,162:6:0:5,0,0:1,0,0:6,0,0 17 126 . A <*> 0 . DP=18;ADF=15,0;ADR=2,0;AD=17,0;I16=15,2,0,0,629,24725,0,0,927,52923,0,0,298,6536,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,162:8:0:8,0:0,0:8,0 0,9,117:3:0:2,0:1,0:3,0 0,18,174:6:0:5,0:1,0:6,0 17 127 . C <*> 0 . DP=18;ADF=15,0;ADR=2,0;AD=17,0;I16=15,2,0,0,627,24331,0,0,927,52923,0,0,299,6549,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,163:8:0:8,0:0,0:8,0 0,9,119:3:0:2,0:1,0:3,0 0,18,160:6:0:5,0:1,0:6,0 17 128 . A <*> 0 . DP=18;ADF=15,0;ADR=2,0;AD=17,0;I16=15,2,0,0,660,26364,0,0,927,52923,0,0,300,6580,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,169:8:0:8,0:0,0:8,0 0,9,121:3:0:2,0:1,0:3,0 0,18,168:6:0:5,0:1,0:6,0 17 129 . A <*> 0 . DP=17;ADF=14,0;ADR=2,0;AD=16,0;I16=14,2,0,0,627,25407,0,0,867,49323,0,0,302,6628,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,168:8:0:8,0:0,0:8,0 0,9,124:3:0:2,0:1,0:3,0 0,15,159:5:0:4,0:1,0:5,0 17 130 . A <*> 0 . DP=17;ADF=14,0;ADR=2,0;AD=16,0;I16=14,2,0,0,627,25419,0,0,867,49323,0,0,304,6692,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,169:8:0:8,0:0,0:8,0 0,9,124:3:0:2,0:1,0:3,0 0,15,152:5:0:4,0:1,0:5,0 17 131 . C <*> 0 . DP=16;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,593,24003,0,0,838,48482,0,0,280,6096,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,167:7:0:7,0:0,0:7,0 0,9,120:3:0:2,0:1,0:3,0 0,15,147:5:0:4,0:1,0:5,0 17 132 . A <*> 0 . DP=16;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,610,25250,0,0,838,48482,0,0,281,6139,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,169:7:0:7,0:0,0:7,0 0,9,120:3:0:2,0:1,0:3,0 0,15,151:5:0:4,0:1,0:5,0 17 133 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,163:7:0:7,0:0,0:7,0 0,9,105:3:0:2,0:1,0:3,0 0,15,150:5:0:4,0:1,0:5,0 17 134 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,177:7:0:7,0:0,0:7,0 0,9,105:3:0:2,0:1,0:3,0 0,15,152:5:0:4,0:1,0:5,0 17 135 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,605,24553,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:7,0:0,0:7,0 0,9,106:3:0:2,0:1,0:3,0 0,15,159:5:0:4,0:1,0:5,0 17 136 . G <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:7,0:0,0:7,0 0,9,105:3:0:2,0:1,0:3,0 0,15,134:5:0:4,0:1,0:5,0 17 137 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,160:7:0:7,0:0,0:7,0 0,9,104:3:0:2,0:1,0:3,0 0,15,139:5:0:4,0:1,0:5,0 17 138 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:7,0:0,0:7,0 0,9,108:3:0:2,0:1,0:3,0 0,15,142:5:0:4,0:1,0:5,0 17 139 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,161:7:0:7,0:0,0:7,0 0,9,106:3:0:2,0:1,0:3,0 0,15,143:5:0:4,0:1,0:5,0 17 140 . A <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,163:7:0:7,0:0,0:7,0 0,9,107:3:0:2,0:1,0:3,0 0,15,153:5:0:4,0:1,0:5,0 17 141 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,158:6:0:6,0:0,0:6,0 0,9,108:3:0:2,0:1,0:3,0 0,15,142:5:0:4,0:1,0:5,0 17 142 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,157:6:0:6,0:0,0:6,0 0,9,97:3:0:2,0:1,0:3,0 0,15,129:5:0:4,0:1,0:5,0 17 143 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,426,13778,0,0,778,44882,0,0,292,6648,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,128:6:0:6,0:0,0:6,0 0,9,95:3:0:2,0:1,0:3,0 0,15,102:5:0:4,0:1,0:5,0 17 144 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,152:6:0:6,0:0,0:6,0 0,9,105:3:0:2,0:1,0:3,0 0,15,129:5:0:4,0:1,0:5,0 17 145 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,153:6:0:6,0:0,0:6,0 0,9,106:3:0:2,0:1,0:3,0 0,15,138:5:0:4,0:1,0:5,0 17 146 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,152:6:0:6,0:0,0:6,0 0,9,103:3:0:2,0:1,0:3,0 0,15,128:5:0:4,0:1,0:5,0 17 147 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,150:6:0:6,0:0,0:6,0 0,9,99:3:0:2,0:1,0:3,0 0,15,140:5:0:4,0:1,0:5,0 17 148 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,157:6:0:6,0:0,0:6,0 0,9,106:3:0:2,0:1,0:3,0 0,15,146:5:0:4,0:1,0:5,0 17 149 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,148:6:0:6,0:0,0:6,0 0,9,109:3:0:2,0:1,0:3,0 0,15,140:5:0:4,0:1,0:5,0 17 150 . T <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,153:6:0:6,0:0,0:6,0 0,6,84:2:0:1,0:1,0:2,0 0,15,152:5:0:4,0:1,0:5,0 17 151 . G <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,157:6:0:6,0:0,0:6,0 0,6,84:2:0:1,0:1,0:2,0 0,15,144:5:0:4,0:1,0:5,0 17 152 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,168:7:0:7,0:0,0:7,0 0,6,84:2:0:1,0:1,0:2,0 0,15,146:5:0:4,0:1,0:5,0 17 153 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,156:7:0:7,0:0,0:7,0 0,6,81:2:0:1,0:1,0:2,0 0,15,153:5:0:4,0:1,0:5,0 17 154 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,159:7:0:7,0:0,0:7,0 0,6,83:2:0:1,0:1,0:2,0 0,15,139:5:0:4,0:1,0:5,0 17 155 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:7,0:0,0:7,0 0,6,85:2:0:1,0:1,0:2,0 0,15,139:5:0:4,0:1,0:5,0 17 156 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,163:7:0:7,0:0,0:7,0 0,6,84:2:0:1,0:1,0:2,0 0,15,150:5:0:4,0:1,0:5,0 17 157 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,169:7:0:7,0:0,0:7,0 0,6,85:2:0:1,0:1,0:2,0 0,15,149:5:0:4,0:1,0:5,0 17 158 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,170:7:0:7,0:0,0:7,0 0,6,84:2:0:1,0:1,0:2,0 0,15,159:5:0:4,0:1,0:5,0 17 159 . A G,<*> 0 . DP=15;ADF=12,1,0;ADR=2,0,0;AD=14,1,0;I16=12,2,1,0,519,19467,5,25,809,47641,60,3600,260,5880,0,0;QS=2.97076,0.0292398,0;SGB=-0.556633;RPBZ=-1.62019;MQBZ=0.267261;MQSBZ=-2.54951;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,157,21,157,157:7:0:7,0,0:0,0,0:7,0,0 0,6,83,6,83,83:2:0:1,0,0:1,0,0:2,0,0 0,10,129,15,132,129:6:0:4,1,0:1,0,0:5,1,0 17 160 . G <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,165:7:0:7,0:0,0:7,0 0,6,85:2:0:1,0:1,0:2,0 0,18,139:6:0:5,0:1,0:6,0 17 161 . A <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,157:7:0:7,0:0,0:7,0 0,6,83:2:0:1,0:1,0:2,0 0,18,162:6:0:5,0:1,0:6,0 17 162 . A <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,558,21206,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,147:7:0:7,0:0,0:7,0 0,6,87:2:0:1,0:1,0:2,0 0,18,167:6:0:5,0:1,0:6,0 17 163 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,505,18789,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,154:7:0:7,0:0,0:7,0 0,6,79:2:0:1,0:1,0:2,0 0,15,138:5:0:4,0:1,0:5,0 17 164 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,131:6:0:6,0:0,0:6,0 0,6,79:2:0:1,0:1,0:2,0 0,18,136:6:0:5,0:1,0:6,0 17 165 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,473,17609,0,0,809,47641,0,0,252,5720,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,149:6:0:6,0:0,0:6,0 0,6,80:2:0:1,0:1,0:2,0 0,18,127:6:0:5,0:1,0:6,0 17 166 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,502,19174,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,145:6:0:6,0:0,0:6,0 0,6,82:2:0:1,0:1,0:2,0 0,18,149:6:0:5,0:1,0:6,0 17 167 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,486,17932,0,0,809,47641,0,0,252,5696,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,132:6:0:6,0:0,0:6,0 0,6,86:2:0:1,0:1,0:2,0 0,18,148:6:0:5,0:1,0:6,0 17 168 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,145:6:0:6,0:0,0:6,0 0,6,82:2:0:1,0:1,0:2,0 0,18,140:6:0:5,0:1,0:6,0 17 169 . C <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,408,14260,0,0,749,44041,0,0,252,5670,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,106:5:0:5,0:0,0:5,0 0,6,76:2:0:1,0:1,0:2,0 0,18,145:6:0:5,0:1,0:6,0 17 170 . C <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,128:5:0:5,0:0,0:5,0 0,6,80:2:0:1,0:1,0:2,0 0,18,143:6:0:5,0:1,0:6,0 17 171 . A <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,134:5:0:5,0:0,0:5,0 0,6,81:2:0:1,0:1,0:2,0 0,18,166:6:0:5,0:1,0:6,0 17 172 . C <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,451,16539,0,0,749,44041,0,0,249,5505,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,138:5:0:5,0:0,0:5,0 0,6,75:2:0:1,0:1,0:2,0 0,18,133:6:0:5,0:1,0:6,0 17 173 . C <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,437,15357,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,121:5:0:5,0:0,0:5,0 0,6,78:2:0:1,0:1,0:2,0 0,18,146:6:0:5,0:1,0:6,0 17 174 . G <*> 0 . DP=13;ADF=12,0;ADR=1,0;AD=13,0;I16=12,1,0,0,356,10710,0,0,749,44041,0,0,248,5464,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,111:5:0:5,0:0,0:5,0 0,3,27:1:0:1,0:0,0:1,0 0,21,116:7:0:6,0:1,0:7,0 17 175 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,515,19433,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,145:6:0:6,0:0,0:6,0 0,3,41:1:0:1,0:0,0:1,0 0,21,175:7:0:6,0:1,0:7,0 17 176 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,146:6:0:6,0:0,0:6,0 0,3,44:1:0:1,0:0,0:1,0 0,21,152:7:0:6,0:1,0:7,0 17 177 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,490,17476,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,139:6:0:6,0:0,0:6,0 0,3,44:1:0:1,0:0,0:1,0 0,21,158:7:0:6,0:1,0:7,0 17 178 . A <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,147:6:0:6,0:0,0:6,0 0,3,42:1:0:1,0:0,0:1,0 0,21,172:7:0:6,0:1,0:7,0 17 179 . A <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,134:6:0:6,0:0,0:6,0 0,3,44:1:0:1,0:0,0:1,0 0,21,170:7:0:6,0:1,0:7,0 17 180 . A <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,432,14702,0,0,809,47641,0,0,256,5534,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,126:6:0:6,0:0,0:6,0 0,3,43:1:0:1,0:0,0:1,0 0,21,148:7:0:6,0:1,0:7,0 17 181 . G <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,469,17345,0,0,809,47641,0,0,257,5571,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,156:6:0:6,0:0,0:6,0 0,3,41:1:0:1,0:0,0:1,0 0,21,142:7:0:6,0:1,0:7,0 17 182 . A <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,150:7:0:7,0:0,0:7,0 0,3,43:1:0:1,0:0,0:1,0 0,21,159:7:0:6,0:1,0:7,0 17 183 . C <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,491,17483,0,0,869,51241,0,0,260,5688,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,159:7:0:7,0:0,0:7,0 0,3,40:1:0:1,0:0,0:1,0 0,21,140:7:0:6,0:1,0:7,0 17 184 . A <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,158:7:0:7,0:0,0:7,0 0,3,41:1:0:1,0:0,0:1,0 0,21,163:7:0:6,0:1,0:7,0 17 185 . C <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,499,17439,0,0,869,51241,0,0,263,5817,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,150:7:0:7,0:0,0:7,0 0,3,38:1:0:1,0:0,0:1,0 0,21,161:7:0:6,0:1,0:7,0 17 186 . G <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,393,11519,0,0,869,51241,0,0,264,5878,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,118:7:0:7,0:0,0:7,0 0,3,32:1:0:1,0:0,0:1,0 0,21,123:7:0:6,0:1,0:7,0 17 187 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,147:6:0:6,0:0,0:6,0 0,3,38:1:0:1,0:0,0:1,0 0,21,172:7:0:6,0:1,0:7,0 17 188 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,147:6:0:6,0:0,0:6,0 0,3,37:1:0:1,0:0,0:1,0 0,21,162:7:0:6,0:1,0:7,0 17 189 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,152:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,21,167:7:0:6,0:1,0:7,0 17 190 . A C,<*> 0 . DP=15;ADF=12,1,0;ADR=2,0,0;AD=14,1,0;I16=12,2,1,0,500,18230,5,25,778,44882,60,3600,243,5381,25,625;QS=2.97664,0.0233645,0;SGB=-0.556633;RPBZ=0;MQBZ=0.392232;MQSBZ=-3.74166;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,138,18,138,138:6:0:6,0,0:0,0,0:6,0,0 0,6,68,6,68,68:2:0:1,0,0:1,0,0:2,0,0 0,12,153,18,156,153:7:0:5,1,0:1,0,0:6,1,0 17 191 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,143:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,21,169:7:0:6,0:1,0:7,0 17 192 . G <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,143:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,21,151:7:0:6,0:1,0:7,0 17 193 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,140:6:0:6,0:0,0:6,0 0,6,63:2:0:1,0:1,0:2,0 0,21,157:7:0:6,0:1,0:7,0 17 194 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,471,16817,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,144:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,18,145:6:0:5,0:1,0:6,0 17 195 . C <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,159:6:0:5,0:1,0:6,0 0,6,71:2:0:1,0:1,0:2,0 0,18,160:6:0:5,0:1,0:6,0 17 196 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,166:6:0:5,0:1,0:6,0 0,6,69:2:0:1,0:1,0:2,0 0,18,138:6:0:5,0:1,0:6,0 17 197 . G <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,164:6:0:5,0:1,0:6,0 0,6,68:2:0:1,0:1,0:2,0 0,18,134:6:0:5,0:1,0:6,0 17 198 . C <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,172:6:0:5,0:1,0:6,0 0,6,70:2:0:1,0:1,0:2,0 0,18,164:6:0:5,0:1,0:6,0 17 199 . T <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,162:6:0:5,0:1,0:6,0 0,6,73:2:0:1,0:1,0:2,0 0,18,154:6:0:5,0:1,0:6,0 17 200 . T <*> 0 . DP=15;ADF=11,0;ADR=4,0;AD=15,0;I16=11,4,0,0,545,19991,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,161:6:0:5,0:1,0:6,0 0,9,89:3:0:1,0:2,0:3,0 0,18,154:6:0:5,0:1,0:6,0 17 201 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,171:7:0:6,0:1,0:7,0 0,9,89:3:0:1,0:2,0:3,0 0,18,157:6:0:5,0:1,0:6,0 17 202 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,178:7:0:6,0:1,0:7,0 0,9,84:3:0:1,0:2,0:3,0 0,18,163:6:0:5,0:1,0:6,0 17 203 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,166:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,18,153:6:0:5,0:1,0:6,0 17 204 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,91:3:0:1,0:2,0:3,0 0,18,163:6:0:5,0:1,0:6,0 17 205 . T <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,188:7:0:6,0:1,0:7,0 0,9,95:3:0:1,0:2,0:3,0 0,18,173:6:0:5,0:1,0:6,0 17 206 . G <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,180:7:0:6,0:1,0:7,0 0,9,89:3:0:1,0:2,0:3,0 0,18,143:6:0:5,0:1,0:6,0 17 207 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,179:7:0:6,0:1,0:7,0 0,9,93:3:0:1,0:2,0:3,0 0,18,151:6:0:5,0:1,0:6,0 17 208 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,184:7:0:6,0:1,0:7,0 0,9,93:3:0:1,0:2,0:3,0 0,18,154:6:0:5,0:1,0:6,0 17 209 . T <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,91:3:0:1,0:2,0:3,0 0,18,146:6:0:5,0:1,0:6,0 17 210 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,151:6:0:5,0:1,0:6,0 17 211 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,153:6:0:5,0:1,0:6,0 17 212 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,181:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,152:6:0:5,0:1,0:6,0 17 213 . T <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,181:7:0:6,0:1,0:7,0 0,9,95:3:0:1,0:2,0:3,0 0,18,165:6:0:5,0:1,0:6,0 17 214 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,539,19501,0,0,836,46564,0,0,262,5732,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,176:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,120:6:0:5,0:1,0:6,0 17 215 . G <*> 0 . DP=15;ADF=12,0;ADR=3,0;AD=15,0;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,15,105:5:0:5,0:0,0:5,0 17 216 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,473,16981,0,0,747,42123,0,0,263,5791,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,12,85:4:0:4,0:0,0:4,0 17 217 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,181:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,12,97:4:0:4,0:0,0:4,0 17 218 . G <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,178:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,12,110:4:0:4,0:0,0:4,0 17 219 . T <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,88:3:0:1,0:2,0:3,0 0,12,89:4:0:4,0:0,0:4,0 17 220 . G <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,495,18407,0,0,747,42123,0,0,267,6079,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,188:7:0:6,0:1,0:7,0 0,9,88:3:0:1,0:2,0:3,0 0,12,84:4:0:4,0:0,0:4,0 17 221 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,488,17688,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,176:7:0:6,0:1,0:7,0 0,9,89:3:0:1,0:2,0:3,0 0,12,101:4:0:4,0:0,0:4,0 17 222 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,479,17747,0,0,747,42123,0,0,267,6203,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,186:7:0:6,0:1,0:7,0 0,9,89:3:0:1,0:2,0:3,0 0,12,73:4:0:4,0:0,0:4,0 17 223 . G T,<*> 0 . DP=13;ADF=9,1,0;ADR=3,0,0;AD=12,1,0;I16=9,3,1,0,412,14782,8,64,627,34923,60,3600,243,5657,25,625;QS=2.96596,0.0340426,0;SGB=-0.556633;RPBZ=1.07052;MQBZ=0.547723;MQSBZ=-3.4641;BQBZ=-1.60577;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,11,166,18,169,167:7:0:5,1,0:1,0,0:6,1,0 0,6,53,6,53,53:2:0:0,0,0:2,0,0:2,0,0 0,12,81,12,81,81:4:0:4,0,0:0,0,0:4,0,0 17 224 . G <*> 0 . DP=12;ADF=9,0;ADR=3,0;AD=12,0;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,168:6:0:5,0:1,0:6,0 0,6,50:2:0:0,0:2,0:2,0 0,12,70:4:0:4,0:0,0:4,0 17 225 . C <*> 0 . DP=12;ADF=9,0;ADR=3,0;AD=12,0;I16=9,3,0,0,390,13960,0,0,627,34923,0,0,272,6466,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,165:6:0:5,0:1,0:6,0 0,6,48:2:0:0,0:2,0:2,0 0,12,86:4:0:4,0:0,0:4,0 17 226 . A G,C,<*> 0 . DP=13;ADF=8,1,0,0;ADR=3,0,1,0;AD=11,1,1,0;I16=8,3,1,1,381,13669,6,18,567,31323,89,4441,248,5894,44,986;QS=2.94293,0.0392157,0.0178571,0;VDB=0.84;SGB=-2.62246;RPBZ=-0.592157;MQBZ=-0.615457;MQSBZ=-3.4641;BQBZ=-2.17723;SCBZ=2.34521;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,159,12,162,159,18,159,162,159:7:0:5,0,0,0:1,0,1,0:6,0,1,0 0,6,53,6,53,53,6,53,53,53:2:0:0,0,0,0:2,0,0,0:2,0,0,0 0,5,79,9,82,80,9,82,80,80:4:0:3,1,0,0:0,0,0,0:3,1,0,0 17 227 . C <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,412,14342,0,0,656,35764,0,0,292,6878,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,190:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,75:4:0:4,0:0,0:4,0 17 228 . C <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,187:7:0:5,0:2,0:7,0 0,6,45:2:0:0,0:2,0:2,0 0,12,96:4:0:4,0:0,0:4,0 17 229 . G <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,368,11524,0,0,656,35764,0,0,292,6898,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,145:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,70:4:0:4,0:0,0:4,0 17 230 . C <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,460,16788,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,186:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,99:4:0:4,0:0,0:4,0 17 231 . C <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,428,15932,0,0,656,35764,0,0,292,6950,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,83:4:0:4,0:0,0:4,0 17 232 . C <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,474,17240,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,197:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,15,101:5:0:5,0:0,0:5,0 17 233 . A <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,192:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,15,119:5:0:5,0:0,0:5,0 17 234 . A <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,15,123:5:0:5,0:0,0:5,0 17 235 . A <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,488,17796,0,0,716,39364,0,0,291,6951,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,186:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,15,115:5:0:5,0:0,0:5,0 17 236 . G <*> 0 . DP=15;ADF=11,0;ADR=4,0;AD=15,0;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,206:8:0:6,0:2,0:8,0 0,6,53:2:0:0,0:2,0:2,0 0,15,103:5:0:5,0:0,0:5,0 17 237 . A C,<*> 0 . DP=14;ADF=9,1,0;ADR=4,0,0;AD=13,1,0;I16=9,4,1,0,465,16877,8,64,656,35764,60,3600,266,6282,25,625;QS=2.93162,0.0683761,0;SGB=-0.556633;RPBZ=1.11754;MQBZ=0.632456;MQSBZ=-3.60555;BQBZ=-1.61959;SCBZ=-0.27735;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,206,24,206,206:8:0:6,0,0:2,0,0:8,0,0 0,6,53,6,53,53:2:0:0,0,0:2,0,0:2,0,0 0,3,84,9,87,87:4:0:3,1,0:0,0,0:3,1,0 17 238 . C <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,211:8:0:6,0:2,0:8,0 0,6,53:2:0:0,0:2,0:2,0 0,12,82:4:0:4,0:0,0:4,0 17 239 . A <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,223:9:0:6,0:3,0:9,0 0,6,50:2:0:0,0:2,0:2,0 0,12,108:4:0:4,0:0,0:4,0 17 240 . C <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,220:9:0:6,0:3,0:9,0 0,6,53:2:0:0,0:2,0:2,0 0,12,106:4:0:4,0:0,0:4,0 17 241 . G <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,456,14780,0,0,776,42964,0,0,292,6688,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,203:9:0:6,0:3,0:9,0 0,6,53:2:0:0,0:2,0:2,0 0,12,64:4:0:4,0:0,0:4,0 17 242 . C <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,242:9:0:6,0:3,0:9,0 0,6,53:2:0:0,0:2,0:2,0 0,12,94:4:0:4,0:0,0:4,0 17 243 . C <*> 0 . DP=16;ADF=10,0;ADR=6,0;AD=16,0;I16=10,6,0,0,531,19777,0,0,805,43805,0,0,297,6597,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,219:9:0:6,0:3,0:9,0 0,9,54:3:0:0,0:3,0:3,0 0,12,104:4:0:4,0:0,0:4,0 17 244 . C <*> 0 . DP=16;ADF=10,0;ADR=6,0;AD=16,0;I16=10,6,0,0,611,23627,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,244:9:0:6,0:3,0:9,0 0,9,72:3:0:0,0:3,0:3,0 0,12,106:4:0:4,0:0,0:4,0 17 245 . A <*> 0 . DP=17;ADF=10,0;ADR=7,0;AD=17,0;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,236:9:0:6,0:3,0:9,0 0,12,93:4:0:0,0:4,0:4,0 0,12,115:4:0:4,0:0,0:4,0 17 246 . T <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,247:10:0:6,0:4,0:10,0 0,12,94:4:0:0,0:4,0:4,0 0,12,98:4:0:4,0:0,0:4,0 17 247 . G <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:6,0:4,0:10,0 0,12,83:4:0:0,0:4,0:4,0 0,12,103:4:0:4,0:0,0:4,0 17 248 . T <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,234:10:0:6,0:4,0:10,0 0,12,86:4:0:0,0:4,0:4,0 0,12,114:4:0:4,0:0,0:4,0 17 249 . C <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,253:10:0:6,0:4,0:10,0 0,12,79:4:0:0,0:4,0:4,0 0,12,112:4:0:4,0:0,0:4,0 17 250 . C <*> 0 . DP=19;ADF=10,0;ADR=9,0;AD=19,0;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,248:10:0:6,0:4,0:10,0 0,12,89:4:0:0,0:4,0:4,0 0,15,142:5:0:4,0:1,0:5,0 17 251 . A <*> 0 . DP=19;ADF=10,0;ADR=9,0;AD=19,0;I16=10,9,0,0,697,26587,0,0,923,49087,0,0,313,6627,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,234:10:0:6,0:4,0:10,0 0,12,97:4:0:0,0:4,0:4,0 0,15,148:5:0:4,0:1,0:5,0 17 252 . G <*> 0 . DP=18;ADF=9,0;ADR=9,0;AD=18,0;I16=9,9,0,0,652,24752,0,0,863,45487,0,0,316,6646,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,243:9:0:5,0:4,0:9,0 0,12,91:4:0:0,0:4,0:4,0 0,15,126:5:0:4,0:1,0:5,0 17 253 . C <*> 0 . DP=19;ADF=9,0;ADR=10,0;AD=19,0;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,247:9:0:5,0:4,0:9,0 0,12,86:4:0:0,0:4,0:4,0 0,18,155:6:0:4,0:2,0:6,0 17 254 . T <*> 0 . DP=20;ADF=10,0;ADR=10,0;AD=20,0;I16=10,10,0,0,731,27661,0,0,952,49928,0,0,323,6751,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,254:10:0:6,0:4,0:10,0 0,12,78:4:0:0,0:4,0:4,0 0,18,164:6:0:4,0:2,0:6,0 17 255 . T <*> 0 . DP=21;ADF=11,0;ADR=10,0;AD=21,0;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,241:11:0:7,0:4,0:11,0 0,12,95:4:0:0,0:4,0:4,0 0,18,161:6:0:4,0:2,0:6,0 17 256 . A <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,110:5:0:0,0:5,0:5,0 0,18,166:6:0:4,0:2,0:6,0 17 257 . T <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,247:11:0:7,0:4,0:11,0 0,15,113:5:0:0,0:5,0:5,0 0,18,168:6:0:4,0:2,0:6,0 17 258 . T <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:7,0:4,0:11,0 0,15,116:5:0:0,0:5,0:5,0 0,18,155:6:0:4,0:2,0:6,0 17 259 . C <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,793,29873,0,0,1049,54897,0,0,353,7377,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,92:5:0:0,0:5,0:5,0 0,18,170:6:0:4,0:2,0:6,0 17 260 . T <*> 0 . DP=21;ADF=10,0;ADR=11,0;AD=21,0;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,118:5:0:0,0:5,0:5,0 0,15,156:5:0:3,0:2,0:5,0 17 261 . G <*> 0 . DP=21;ADF=10,0;ADR=11,0;AD=21,0;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:7,0:4,0:11,0 0,15,111:5:0:0,0:5,0:5,0 0,15,122:5:0:3,0:2,0:5,0 17 262 . C <*> 0 . DP=22;ADF=10,0;ADR=12,0;AD=22,0;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,99:5:0:0,0:5,0:5,0 0,18,164:6:0:3,0:3,0:6,0 17 263 . C <*> 0 . DP=22;ADF=10,0;ADR=12,0;AD=22,0;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,98:5:0:0,0:5,0:5,0 0,18,168:6:0:3,0:3,0:6,0 17 264 . C <*> 0 . DP=22;ADF=10,0;ADR=12,0;AD=22,0;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,104:5:0:0,0:5,0:5,0 0,18,172:6:0:3,0:3,0:6,0 17 265 . A <*> 0 . DP=21;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,114:5:0:0,0:5,0:5,0 0,15,129:5:0:2,0:3,0:5,0 17 266 . G <*> 0 . DP=21;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,754,28204,0,0,989,51297,0,0,394,8458,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,99:5:0:0,0:5,0:5,0 0,15,138:5:0:2,0:3,0:5,0 17 267 . T G,<*> 0 . DP=21;ADF=9,0,0;ADR=11,1,0;AD=20,1,0;I16=9,11,0,1,739,27465,8,64,960,50456,29,841,373,7935,25,625;QS=2.94203,0.057971,0;SGB=-0.556633;RPBZ=-0.330396;MQBZ=-1.23153;MQSBZ=-3.3021;BQBZ=-1.66282;SCBZ=2.91633;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254,33,254,254:11:0:7,0,0:4,0,0:11,0,0 0,6,93,12,96,96:5:0:0,0,0:4,1,0:4,1,0 0,15,149,15,149,149:5:0:2,0,0:3,0,0:5,0,0 17 268 . T <*> 0 . DP=21;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,238:11:0:7,0:4,0:11,0 0,15,110:5:0:0,0:5,0:5,0 0,15,156:5:0:2,0:3,0:5,0 17 269 . C <*> 0 . DP=22;ADF=9,0;ADR=13,0;AD=22,0;I16=9,13,0,0,767,28641,0,0,1018,52138,0,0,406,8836,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,91:5:0:0,0:5,0:5,0 0,15,154:5:0:2,0:3,0:5,0 17 270 . C <*> 0 . DP=22;ADF=9,0;ADR=13,0;AD=22,0;I16=9,13,0,0,766,28210,0,0,1018,52138,0,0,410,8962,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,98:5:0:0,0:5,0:5,0 0,15,143:5:0:2,0:3,0:5,0 17 271 . T <*> 0 . DP=22;ADF=9,0;ADR=13,0;AD=22,0;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,113:5:0:0,0:5,0:5,0 0,15,152:5:0:2,0:3,0:5,0 17 272 . C <*> 0 . DP=22;ADF=9,0;ADR=13,0;AD=22,0;I16=9,13,0,0,815,31449,0,0,1018,52138,0,0,415,9143,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,97:5:0:0,0:5,0:5,0 0,15,149:5:0:2,0:3,0:5,0 17 273 . T C,<*> 0 . DP=22;ADF=9,0,0;ADR=12,1,0;AD=21,1,0;I16=9,12,0,1,798,30664,5,25,989,51297,29,841,392,8620,25,625;QS=2.96094,0.0390625,0;SGB=-0.556633;RPBZ=-0.236567;MQBZ=-1.16701;MQSBZ=-3.42286;BQBZ=-1.66779;SCBZ=3.00076;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255,36,255,255:12:0:7,0,0:5,0,0:12,0,0 0,7,89,12,92,90:5:0:0,0,0:4,1,0:4,1,0 0,15,161,15,161,161:5:0:2,0,0:3,0,0:5,0,0 17 274 . C <*> 0 . DP=22;ADF=9,0;ADR=13,0;AD=22,0;I16=9,13,0,0,767,28193,0,0,1018,52138,0,0,419,9371,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,101:5:0:0,0:5,0:5,0 0,15,144:5:0:2,0:3,0:5,0 17 275 . C <*> 0 . DP=20;ADF=7,0;ADR=13,0;AD=20,0;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,15,114:5:0:0,0:5,0:5,0 0,12,122:4:0:1,0:3,0:4,0 17 276 . A <*> 0 . DP=20;ADF=7,0;ADR=13,0;AD=20,0;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,253:11:0:6,0:5,0:11,0 0,15,122:5:0:0,0:5,0:5,0 0,12,124:4:0:1,0:3,0:4,0 17 277 . G <*> 0 . DP=20;ADF=7,0;ADR=13,0;AD=20,0;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,15,114:5:0:0,0:5,0:5,0 0,12,121:4:0:1,0:3,0:4,0 17 278 . A C,<*> 0 . DP=21;ADF=6,1,0;ADR=14,0,0;AD=20,1,0;I16=6,14,1,0,722,26452,7,49,867,42179,60,3600,415,9521,11,121;QS=2.97935,0.020649,0;SGB=-0.556633;RPBZ=1.65198;MQBZ=1.0247;MQSBZ=-3.24037;BQBZ=-1.66667;SCBZ=-0.324037;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,22,231,30,234,231:11:0:5,1,0:5,0,0:10,1,0 0,18,123,18,123,123:6:0:0,0,0:6,0,0:6,0,0 0,12,121,12,121,121:4:0:1,0,0:3,0,0:4,0,0 17 279 . A <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,123:6:0:0,0:6,0:6,0 0,12,122:4:0:1,0:3,0:4,0 17 280 . A <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,253:12:0:6,0:6,0:12,0 0,18,130:6:0:0,0:6,0:6,0 0,12,129:4:0:1,0:3,0:4,0 17 281 . G <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,122:6:0:0,0:6,0:6,0 0,12,123:4:0:1,0:3,0:4,0 17 282 . G <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,253:12:0:6,0:6,0:12,0 0,18,124:6:0:0,0:6,0:6,0 0,12,119:4:0:1,0:3,0:4,0 17 283 . C <*> 0 . DP=23;ADF=7,0;ADR=16,0;AD=23,0;I16=7,16,0,0,829,31789,0,0,1016,50220,0,0,431,9599,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,125:6:0:0,0:6,0:6,0 0,15,122:5:0:1,0:4,0:5,0 17 284 . T <*> 0 . DP=23;ADF=7,0;ADR=16,0;AD=23,0;I16=7,16,0,0,895,35059,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,126:6:0:0,0:6,0:6,0 0,15,138:5:0:1,0:4,0:5,0 17 285 . G <*> 0 . DP=23;ADF=7,0;ADR=16,0;AD=23,0;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,119:6:0:0,0:6,0:6,0 0,15,132:5:0:1,0:4,0:5,0 17 286 . C <*> 0 . DP=24;ADF=8,0;ADR=16,0;AD=24,0;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,21,150:7:0:1,0:6,0:7,0 0,15,134:5:0:1,0:4,0:5,0 17 287 . A <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,178:8:0:2,0:6,0:8,0 0,15,133:5:0:1,0:4,0:5,0 17 288 . T <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,184:8:0:2,0:6,0:8,0 0,15,146:5:0:1,0:4,0:5,0 17 289 . G <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,185:8:0:2,0:6,0:8,0 0,15,136:5:0:1,0:4,0:5,0 17 290 . G <*> 0 . DP=23;ADF=8,0;ADR=15,0;AD=23,0;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,240:11:0:5,0:6,0:11,0 0,21,164:7:0:2,0:5,0:7,0 0,15,126:5:0:1,0:4,0:5,0 17 291 . T <*> 0 . DP=24;ADF=8,0;ADR=16,0;AD=24,0;I16=8,16,0,0,850,31716,0,0,1107,56579,0,0,434,9648,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,244:11:0:5,0:6,0:11,0 0,21,168:7:0:2,0:5,0:7,0 0,18,138:6:0:1,0:5,0:6,0 17 292 . T <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,253:11:0:5,0:6,0:11,0 0,24,181:8:0:3,0:5,0:8,0 0,18,156:6:0:1,0:5,0:6,0 17 293 . G <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,946,35376,0,0,1227,63779,0,0,439,9713,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,196:8:0:3,0:5,0:8,0 0,18,148:6:0:1,0:5,0:6,0 17 294 . A <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,252:12:0:6,0:6,0:12,0 0,24,201:8:0:3,0:5,0:8,0 0,18,161:6:0:1,0:5,0:6,0 17 295 . C <*> 0 . DP=25;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,909,34117,0,0,1198,62938,0,0,447,9833,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,183:8:0:3,0:5,0:8,0 0,18,159:6:0:1,0:5,0:6,0 17 296 . A <*> 0 . DP=25;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,169:8:0:3,0:5,0:8,0 0,18,169:6:0:1,0:5,0:6,0 17 297 . C G,<*> 0 . DP=25;ADF=9,1,0;ADR=15,0,0;AD=24,1,0;I16=9,15,1,0,901,34305,4,16,1138,59338,60,3600,445,9901,10,100;QS=2.98261,0.0173913,0;SGB=-0.556633;RPBZ=-1.24856;MQBZ=0.806872;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.368383;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255,33,255,255:11:0:6,0,0:5,0,0:11,0,0 0,15,168,21,171,168:8:0:2,1,0:5,0,0:7,1,0 0,18,161,18,161,161:6:0:1,0,0:5,0,0:6,0,0 17 298 . A <*> 0 . DP=26;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,184:8:0:3,0:5,0:8,0 0,21,191:7:0:2,0:5,0:7,0 17 299 . C <*> 0 . DP=27;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,193:8:0:3,0:5,0:8,0 0,21,189:7:0:2,0:5,0:7,0 17 300 . A <*> 0 . DP=27;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,204:8:0:3,0:5,0:8,0 0,21,210:7:0:2,0:5,0:7,0 17 301 . G <*> 0 . DP=25;ADF=10,0;ADR=14,0;AD=24,0;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,21,195:7:0:3,0:4,0:7,0 0,21,196:7:0:2,0:5,0:7,0 17 302 . T <*> 0 . DP=25;ADF=10,0;ADR=14,0;AD=24,0;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,231:10:0:5,0:5,0:10,0 0,21,172:7:0:3,0:4,0:7,0 0,21,202:7:0:2,0:5,0:7,0 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;ADF=2,8;ADR=4,11;AD=6,19;I16=2,4,8,11,240,9600,760,30400,236,10564,993,55133,109,2229,377,8629;QS=0.539485,2.46052;VDB=0.241622;SGB=-4.22417;RPBZ=1.11989;MQBZ=1.47646;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.268121;MQ0F=0 PL:DP:SP:ADF:ADR:AD 161,0,99:11:6:1,4:4,2:5,6 158,0,14:7:0:1,2:0,4:1,6 201,21,0:7:0:0,2:0,5:0,7 17 303 . G <*> 0 . DP=25;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,968,37972,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,21,197:7:0:3,0:4,0:7,0 0,21,195:7:0:2,0:5,0:7,0 17 304 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,206:8:0:4,0:4,0:8,0 0,24,200:8:0:2,0:6,0:8,0 17 305 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,213:8:0:4,0:4,0:8,0 0,24,211:8:0:2,0:6,0:8,0 17 306 . T <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,207:8:0:4,0:4,0:8,0 0,24,217:8:0:2,0:6,0:8,0 17 307 . G <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,989,37911,0,0,1318,70138,0,0,523,11823,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,189:8:0:4,0:4,0:8,0 0,24,203:8:0:2,0:6,0:8,0 17 308 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,178:8:0:4,0:4,0:8,0 0,24,185:8:0:2,0:6,0:8,0 17 309 . G <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,243:11:0:5,0:6,0:11,0 0,24,183:8:0:4,0:4,0:8,0 0,24,205:8:0:2,0:6,0:8,0 17 310 . A <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,200:8:0:4,0:4,0:8,0 0,24,217:8:0:2,0:6,0:8,0 17 311 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,215:8:0:4,0:4,0:8,0 0,24,210:8:0:2,0:6,0:8,0 17 312 . A <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,237:10:0:4,0:6,0:10,0 0,24,215:8:0:4,0:4,0:8,0 0,24,218:8:0:2,0:6,0:8,0 17 313 . A <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,235:10:0:4,0:6,0:10,0 0,24,219:8:0:4,0:4,0:8,0 0,24,215:8:0:2,0:6,0:8,0 17 314 . A <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,250:11:0:4,0:7,0:11,0 0,24,217:8:0:4,0:4,0:8,0 0,24,227:8:0:2,0:6,0:8,0 17 315 . G <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,1023,40789,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:4,0:6,0:10,0 0,24,216:8:0:4,0:4,0:8,0 0,24,225:8:0:2,0:6,0:8,0 17 316 . C <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,992,39446,0,0,1349,72897,0,0,564,12918,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,27,184:9:0:4,0:5,0:9,0 0,24,224:8:0:2,0:6,0:8,0 17 317 . T <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1025,40437,0,0,1349,72897,0,0,567,12957,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,27,229:9:0:4,0:5,0:9,0 0,24,206:8:0:2,0:6,0:8,0 17 318 . G <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,249:10:0:4,0:6,0:10,0 0,27,235:9:0:4,0:5,0:9,0 0,24,208:8:0:2,0:6,0:8,0 17 319 . A <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1005,38775,0,0,1349,72897,0,0,572,13050,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,249:10:0:4,0:6,0:10,0 0,27,228:9:0:4,0:5,0:9,0 0,24,196:8:0:2,0:6,0:8,0 17 320 . A <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,247:10:0:4,0:6,0:10,0 0,27,230:9:0:4,0:5,0:9,0 0,24,211:8:0:2,0:6,0:8,0 17 321 . T <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,253:10:0:4,0:6,0:10,0 0,27,214:9:0:4,0:5,0:9,0 0,24,218:8:0:2,0:6,0:8,0 17 322 . G <*> 0 . DP=28;ADF=10,0;ADR=18,0;AD=28,0;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,27,226:9:0:4,0:5,0:9,0 0,27,223:9:0:2,0:7,0:9,0 17 323 . C <*> 0 . DP=28;ADF=10,0;ADR=18,0;AD=28,0;I16=10,18,0,0,1076,42700,0,0,1409,76497,0,0,573,13003,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,27,225:9:0:4,0:5,0:9,0 0,27,208:9:0:2,0:7,0:9,0 17 324 . T <*> 0 . DP=30;ADF=12,0;ADR=18,0;AD=30,0;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,253:10:0:4,0:6,0:10,0 0,27,237:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 325 . A <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,208:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 326 . T <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,216:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 327 . C <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,198:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 328 . A <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,226:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 329 . T <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,237:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 330 . T <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:5,0:6,0:11,0 0,27,231:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 331 . T <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,222:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 17 332 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,27,214:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 333 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,27,223:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 334 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,27,221:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 17 335 . A G,<*> 0 . DP=32;ADF=13,1,0;ADR=18,0,0;AD=31,1,0;I16=13,18,1,0,1084,40336,4,16,1589,87297,60,3600,555,11943,0,0;QS=2.98919,0.0108108,0;SGB=-0.556633;RPBZ=-1.67936;MQBZ=0.622171;MQSBZ=-2.25492;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,252,33,252,252:11:0:5,0,0:6,0,0:11,0,0 0,27,219,27,219,219:9:0:4,0,0:5,0,0:9,0,0 0,25,245,33,248,245:12:0:4,1,0:7,0,0:11,1,0 17 336 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1094,39794,0,0,1649,90897,0,0,555,11935,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,212:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 17 337 . C A,<*> 0 . DP=32;ADF=14,0,0;ADR=17,1,0;AD=31,1,0;I16=14,17,0,1,1125,42481,5,25,1612,89528,37,1369,536,11590,18,324;QS=2.98113,0.0188679,0;SGB=-0.556633;RPBZ=0.812593;MQBZ=-1.03695;MQSBZ=-2.25492;BQBZ=-1.68353;SCBZ=-0.258065;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255,33,255,255:11:0:5,0,0:6,0,0:11,0,0 0,17,195,24,198,195:9:0:4,0,0:4,1,0:8,1,0 0,36,255,36,255,255:12:0:5,0,0:7,0,0:12,0,0 17 338 . T <*> 0 . DP=30;ADF=14,0;ADR=16,0;AD=30,0;I16=14,16,0,0,1190,47898,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,24,226:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 339 . C <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,185:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 340 . C <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,221:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 341 . T <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,216:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 342 . T <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,210:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 343 . G <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1157,43751,0,0,1649,90897,0,0,554,11978,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,249:11:0:5,0:6,0:11,0 0,27,218:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 17 344 . C <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,217:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 17 345 . T <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,221:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 346 . G <*> 0 . DP=31;ADF=15,0;ADR=16,0;AD=31,0;I16=15,16,0,0,1142,43222,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,212:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 347 . G <*> 0 . DP=31;ADF=15,0;ADR=16,0;AD=31,0;I16=15,16,0,0,1124,42252,0,0,1620,90056,0,0,560,12414,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,251:11:0:6,0:5,0:11,0 0,24,207:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 17 348 . T <*> 0 . DP=32;ADF=16,0;ADR=16,0;AD=32,0;I16=16,16,0,0,1149,43023,0,0,1680,93656,0,0,562,12556,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,242:11:0:6,0:5,0:11,0 0,27,228:9:0:5,0:4,0:9,0 0,36,255:12:0:5,0:7,0:12,0 17 349 . T <*> 0 . DP=32;ADF=16,0;ADR=16,0;AD=32,0;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,246:11:0:6,0:5,0:11,0 0,27,230:9:0:5,0:4,0:9,0 0,36,255:12:0:5,0:7,0:12,0 17 350 . T <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,249:11:0:6,0:5,0:11,0 0,27,230:9:0:5,0:4,0:9,0 0,33,255:11:0:5,0:6,0:11,0 17 351 . G <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,27,212:9:0:5,0:4,0:9,0 0,33,255:11:0:5,0:6,0:11,0 17 352 . A <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1162,45664,0,0,1651,92815,0,0,569,13029,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,27,230:9:0:5,0:4,0:9,0 0,33,255:11:0:5,0:6,0:11,0 17 353 . G <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,27,231:9:0:5,0:4,0:9,0 0,30,255:10:0:5,0:5,0:10,0 17 354 . A <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,225:9:0:4,0:5,0:9,0 0,27,244:9:0:5,0:4,0:9,0 0,30,255:10:0:5,0:5,0:10,0 17 355 . G T,<*> 0 . DP=28;ADF=14,0,0;ADR=13,1,0;AD=27,1,0;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPBZ=0.185772;MQBZ=0.520126;MQSBZ=-1.7696;BQBZ=0.683978;SCBZ=-0.27735;MQ0F=0 PL:DP:SP:ADF:ADR:AD 14,0,200,38,203,231:9:0:4,0,0:4,1,0:8,1,0 0,27,222,27,222,222:9:0:5,0,0:4,0,0:9,0,0 0,30,255,30,255,255:10:0:5,0,0:5,0,0:10,0,0 17 356 . G <*> 0 . DP=27;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,228:9:0:4,0:5,0:9,0 0,24,201:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 357 . C <*> 0 . DP=28;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1026,39496,0,0,1525,87005,0,0,575,13209,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,24,205:8:0:5,0:3,0:8,0 0,30,252:10:0:5,0:5,0:10,0 17 358 . A <*> 0 . DP=28;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,254:10:0:5,0:5,0:10,0 0,24,197:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 359 . G T,<*> 0 . DP=29;ADF=15,0,0;ADR=13,1,0;AD=28,1,0;I16=15,13,0,1,1085,42761,10,100,1525,87005,60,3600,552,12620,25,625;QS=2.96032,0.0396825,0;SGB=-0.556633;RPBZ=-0.119611;MQBZ=0.456435;MQSBZ=-1.53333;BQBZ=-1.68246;SCBZ=5.2915;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255,30,255,255:10:0:5,0,0:5,0,0:10,0,0 0,13,178,21,181,180:8:0:5,0,0:2,1,0:7,1,0 0,33,255,33,255,255:11:0:5,0,0:6,0,0:11,0,0 17 360 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:5,0:5,0:10,0 0,24,220:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 361 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:5,0:5,0:10,0 0,24,219:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 362 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,218:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 363 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,213:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 364 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,250:11:0:6,0:5,0:11,0 0,24,205:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 365 . G <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,211:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 366 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,211:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 367 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,204:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 368 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,208:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 369 . T G,<*> 0 . DP=28;ADF=16,0,0;ADR=11,1,0;AD=27,1,0;I16=16,11,0,1,1037,40275,6,36,1496,86164,60,3600,548,12256,25,625;QS=2.97683,0.023166,0;SGB=-0.556633;RPBZ=0.12395;MQBZ=0.408248;MQSBZ=-1.37784;BQBZ=-1.68703;SCBZ=5.19615;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,250,30,250,250:10:0:6,0,0:4,0,0:10,0,0 0,15,189,21,192,190:8:0:5,0,0:2,1,0:7,1,0 0,30,255,30,255,255:10:0:5,0,0:5,0,0:10,0,0 17 370 . C <*> 0 . DP=28;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:6,0:4,0:10,0 0,24,201:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 371 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:6,0:4,0:10,0 0,24,227:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 372 . C <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,215:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 373 . A <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,220:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 374 . T <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,221:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 375 . A T,<*> 0 . DP=31;ADF=17,0,0;ADR=13,1,0;AD=30,1,0;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPBZ=-1.45432;MQBZ=0.3849;MQSBZ=-1.26404;BQBZ=-1.68488;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255,36,255,255:12:0:7,0,0:5,0,0:12,0,0 0,24,218,24,218,218:8:0:5,0,0:3,0,0:8,0,0 0,18,255,30,255,255:11:0:5,0,0:5,1,0:10,1,0 17 376 . G <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,24,220:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 377 . T <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1116,41750,0,0,1736,100564,0,0,543,11985,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,24,211:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 17 378 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,186:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 379 . G <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1060,40230,0,0,1678,98882,0,0,541,11897,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,21,187:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 380 . C <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1094,42792,0,0,1678,98882,0,0,539,11797,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,21,184:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 381 . T <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1167,47337,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,21,211:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 382 . T <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1062,40514,0,0,1678,98882,0,0,535,11693,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,21,182:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 383 . T <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1059,39847,0,0,1678,98882,0,0,532,11638,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,21,172:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 384 . A C,<*> 0 . DP=31;ADF=19,0,0;ADR=11,1,0;AD=30,1,0;I16=19,11,0,1,1077,39885,4,16,1738,102482,60,3600,504,10988,25,625;QS=2.98419,0.0158103,0;SGB=-0.556633;RPBZ=0.615229;MQBZ=0.262613;MQSBZ=-0.333409;BQBZ=-1.68746;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255,39,255,255:13:0:8,0,0:5,0,0:13,0,0 0,15,171,21,174,171:8:0:6,0,0:1,1,0:7,1,0 0,30,255,30,255,255:10:0:5,0,0:5,0,0:10,0,0 17 385 . C <*> 0 . DP=31;ADF=19,0;ADR=12,0;AD=31,0;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,24,186:8:0:6,0:2,0:8,0 0,30,255:10:0:5,0:5,0:10,0 17 386 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,191:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 387 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,187:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 388 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,180:6:0:4,0:2,0:6,0 0,30,255:10:0:5,0:5,0:10,0 17 389 . G <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,171:6:0:4,0:2,0:6,0 0,30,255:10:0:5,0:5,0:10,0 17 390 . C <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,162:6:0:4,0:2,0:6,0 0,30,255:10:0:5,0:5,0:10,0 17 391 . A <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,163:6:0:4,0:2,0:6,0 0,30,255:10:0:6,0:4,0:10,0 17 392 . T <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,153:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 17 393 . A <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,133:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 17 394 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,141:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 17 395 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,164:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 17 396 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,158:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 17 397 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,149:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 17 398 . A <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1025,38361,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,144:5:0:3,0:2,0:5,0 0,30,255:10:0:6,0:4,0:10,0 17 399 . A <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1023,38949,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,140:5:0:3,0:2,0:5,0 0,30,255:10:0:6,0:4,0:10,0 17 400 . A <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1070,40554,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,159:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 401 . A C,<*> 0 . DP=29;ADF=17,0,0;ADR=11,1,0;AD=28,1,0;I16=17,11,0,1,1063,41001,8,64,1587,92523,60,3600,501,11113,25,625;QS=2.97985,0.0201511,0;SGB=-0.556633;RPBZ=-0.478622;MQBZ=0.339683;MQSBZ=0.29364;BQBZ=-1.68267;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255,39,255,255:13:0:8,0,0:5,0,0:13,0,0 0,15,160,15,160,160:5:0:3,0,0:2,0,0:5,0,0 0,22,255,30,255,255:11:0:6,0,0:4,1,0:10,1,0 17 402 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1076,40740,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,149:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 403 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,148:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 404 . G <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,131:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 405 . T <*> 0 . DP=27;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,997,37951,0,0,1558,91682,0,0,526,11592,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,12,109:4:0:2,0:2,0:4,0 0,30,255:10:0:6,0:4,0:10,0 17 406 . G <*> 0 . DP=27;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,12,125:4:0:2,0:2,0:4,0 0,30,247:10:0:6,0:4,0:10,0 17 407 . A <*> 0 . DP=27;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,12,125:4:0:2,0:2,0:4,0 0,30,255:10:0:6,0:4,0:10,0 17 408 . C <*> 0 . DP=28;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,1013,38245,0,0,1618,95282,0,0,525,11505,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,12,114:4:0:2,0:2,0:4,0 0,30,244:10:0:6,0:4,0:10,0 17 409 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,12,131:4:0:2,0:2,0:4,0 0,33,255:11:0:7,0:4,0:11,0 17 410 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,12,125:4:0:2,0:2,0:4,0 0,33,255:11:0:7,0:4,0:11,0 17 411 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1022,37928,0,0,1678,98882,0,0,522,11342,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,12,111:4:0:2,0:2,0:4,0 0,33,255:11:0:7,0:4,0:11,0 17 412 . C T,<*> 0 . DP=30;ADF=17,1,0;ADR=12,0,0;AD=29,1,0;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPBZ=-0.40473;MQBZ=0.267261;MQSBZ=-0.293785;BQBZ=-1.6942;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255,42,255,255:15:0:8,1,0:6,0,0:14,1,0 0,12,124,12,124,124:4:0:2,0,0:2,0,0:4,0,0 0,33,255,33,255,255:11:0:7,0,0:4,0,0:11,0,0 17 413 . A <*> 0 . DP=31;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,102:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 17 414 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,109:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 17 415 . G <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,110:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 17 416 . G <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1089,41309,0,0,1738,102482,0,0,529,11381,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,114:3:0:2,0:1,0:3,0 0,33,252:11:0:7,0:4,0:11,0 17 417 . C <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,108:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 17 418 . A <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,111:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 17 419 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,112:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 17 420 . A <*> 0 . DP=31;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,108:3:0:2,0:1,0:3,0 0,36,255:12:0:7,0:5,0:12,0 17 421 . A <*> 0 . DP=33;ADF=19,0;ADR=14,0;AD=33,0;I16=19,14,0,0,1211,45581,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,113:3:0:2,0:1,0:3,0 0,42,255:14:0:8,0:6,0:14,0 17 422 . A <*> 0 . DP=33;ADF=19,0;ADR=14,0;AD=33,0;I16=19,14,0,0,1221,46833,0,0,1887,110523,0,0,535,11707,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,116:3:0:2,0:1,0:3,0 0,42,255:14:0:8,0:6,0:14,0 17 423 . T <*> 0 . DP=32;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,110:3:0:2,0:1,0:3,0 0,39,255:13:0:8,0:5,0:13,0 17 424 . A <*> 0 . DP=32;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,106:3:0:2,0:1,0:3,0 0,39,255:13:0:8,0:5,0:13,0 17 425 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,111:3:0:2,0:1,0:3,0 0,33,249:11:0:6,0:5,0:11,0 17 426 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1005,36625,0,0,1647,96123,0,0,544,11912,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,105:3:0:2,0:1,0:3,0 0,33,227:11:0:6,0:5,0:11,0 17 427 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,111:3:0:2,0:1,0:3,0 0,33,242:11:0:6,0:5,0:11,0 17 428 . C <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,111:3:0:2,0:1,0:3,0 0,33,254:11:0:6,0:5,0:11,0 17 429 . T <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,115:3:0:2,0:1,0:3,0 0,33,255:11:0:6,0:5,0:11,0 17 430 . G <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,112:3:0:2,0:1,0:3,0 0,33,246:11:0:6,0:5,0:11,0 17 431 . G <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1012,37006,0,0,1707,99723,0,0,553,12255,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,101:3:0:2,0:1,0:3,0 0,33,224:11:0:6,0:5,0:11,0 17 432 . T <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,9,114:3:0:2,0:1,0:3,0 0,30,255:10:0:5,0:5,0:10,0 17 433 . T <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,969,35651,0,0,1587,92523,0,0,559,12467,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,9,112:3:0:2,0:1,0:3,0 0,30,229:10:0:5,0:5,0:10,0 17 434 . T <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,98:3:0:2,0:1,0:3,0 0,30,243:10:0:5,0:5,0:10,0 17 435 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1035,38091,0,0,1647,96123,0,0,562,12596,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,103:3:0:2,0:1,0:3,0 0,30,237:10:0:5,0:5,0:10,0 17 436 . T <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,110:3:0:2,0:1,0:3,0 0,27,223:9:0:4,0:5,0:9,0 17 437 . T G,<*> 0 . DP=28;ADF=13,1,0;ADR=14,0,0;AD=27,1,0;I16=13,14,1,0,990,36832,6,36,1558,91682,29,841,549,12435,16,256;QS=2.9781,0.0218978,0;SGB=-0.556633;RPBZ=-1.36214;MQBZ=-2.88675;MQSBZ=0.6;BQBZ=-1.67909;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255,48,255,255:16:0:8,0,0:8,0,0:16,0,0 0,9,109,9,109,109:3:0:2,0,0:1,0,0:3,0,0 0,17,200,24,203,201:9:0:3,1,0:5,0,0:8,1,0 17 438 . A <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,984,35784,0,0,1587,92523,0,0,565,12707,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,107:3:0:2,0:1,0:3,0 0,27,220:9:0:4,0:5,0:9,0 17 439 . C <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,107:3:0:2,0:1,0:3,0 0,27,224:9:0:4,0:5,0:9,0 17 440 . A <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,115:3:0:2,0:1,0:3,0 0,27,247:9:0:4,0:5,0:9,0 17 441 . G <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,104:3:0:2,0:1,0:3,0 0,27,198:9:0:4,0:5,0:9,0 17 442 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1079,40643,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,101:3:0:2,0:1,0:3,0 0,27,233:9:0:4,0:5,0:9,0 17 443 . A <*> 0 . DP=30;ADF=14,0;ADR=15,0;AD=29,0;I16=14,15,0,0,1153,46639,0,0,1647,96123,0,0,532,12036,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,130:3:0:1,0:2,0:3,0 0,27,246:9:0:4,0:5,0:9,0 17 444 . G <*> 0 . DP=29;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1083,43077,0,0,1587,92523,0,0,533,12103,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,6,98:2:0:1,0:1,0:2,0 0,27,227:9:0:4,0:5,0:9,0 17 445 . C <*> 0 . DP=30;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1090,42406,0,0,1647,96123,0,0,534,12196,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,122:3:0:2,0:1,0:3,0 0,27,219:9:0:4,0:5,0:9,0 17 446 . A <*> 0 . DP=30;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1092,42240,0,0,1647,96123,0,0,535,12265,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,127:3:0:2,0:1,0:3,0 0,27,232:9:0:4,0:5,0:9,0 17 447 . C <*> 0 . DP=29;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1095,43635,0,0,1618,95282,0,0,534,12208,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,125:3:0:2,0:1,0:3,0 0,27,235:9:0:4,0:5,0:9,0 17 448 . T <*> 0 . DP=29;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1104,44276,0,0,1618,95282,0,0,533,12173,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,130:3:0:2,0:1,0:3,0 0,27,240:9:0:4,0:5,0:9,0 17 449 . A <*> 0 . DP=28;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,1071,43181,0,0,1558,91682,0,0,533,12159,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,6,97:2:0:1,0:1,0:2,0 0,27,245:9:0:4,0:5,0:9,0 17 450 . G <*> 0 . DP=28;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,1053,42427,0,0,1558,91682,0,0,533,12165,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,6,98:2:0:1,0:1,0:2,0 0,27,233:9:0:4,0:5,0:9,0 17 451 . A <*> 0 . DP=28;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,1003,38887,0,0,1558,91682,0,0,533,12191,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,6,100:2:0:1,0:1,0:2,0 0,27,244:9:0:4,0:5,0:9,0 17 452 . A <*> 0 . DP=31;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1071,40901,0,0,1738,102482,0,0,533,12237,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,121:3:0:2,0:1,0:3,0 0,27,225:9:0:4,0:5,0:9,0 17 453 . A <*> 0 . DP=31;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1057,40647,0,0,1738,102482,0,0,536,12306,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,129:3:0:2,0:1,0:3,0 0,27,225:9:0:4,0:5,0:9,0 17 454 . A <*> 0 . DP=31;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1156,45762,0,0,1738,102482,0,0,540,12400,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,9,130:3:0:2,0:1,0:3,0 0,30,255:10:0:5,0:5,0:10,0 17 455 . T <*> 0 . DP=32;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1140,43710,0,0,1775,103851,0,0,543,12419,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,9,124:3:0:2,0:1,0:3,0 0,33,255:11:0:5,0:6,0:11,0 17 456 . G <*> 0 . DP=32;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1154,44790,0,0,1775,103851,0,0,547,12465,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,9,128:3:0:2,0:1,0:3,0 0,33,250:11:0:5,0:6,0:11,0 17 457 . C <*> 0 . DP=33;ADF=18,0;ADR=14,0;AD=32,0;I16=18,14,0,0,1205,46913,0,0,1835,107451,0,0,552,12538,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,131:3:0:2,0:1,0:3,0 0,33,255:11:0:5,0:6,0:11,0 17 458 . A <*> 0 . DP=33;ADF=18,0;ADR=14,0;AD=32,0;I16=18,14,0,0,1208,46550,0,0,1835,107451,0,0,558,12590,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,122:3:0:2,0:1,0:3,0 0,33,255:11:0:5,0:6,0:11,0 17 459 . T <*> 0 . DP=33;ADF=18,0;ADR=14,0;AD=32,0;I16=18,14,0,0,1153,43773,0,0,1835,107451,0,0,563,12625,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,105:3:0:2,0:1,0:3,0 0,33,255:11:0:5,0:6,0:11,0 17 460 . G <*> 0 . DP=32;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1199,47305,0,0,1775,103851,0,0,568,12642,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,128:3:0:2,0:1,0:3,0 0,30,255:10:0:5,0:5,0:10,0 17 461 . T <*> 0 . DP=32;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1194,47178,0,0,1775,103851,0,0,572,12640,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,127:3:0:2,0:1,0:3,0 0,30,255:10:0:5,0:5,0:10,0 17 462 . G <*> 0 . DP=32;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1169,46001,0,0,1775,103851,0,0,577,12669,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,12,131:4:0:3,0:1,0:4,0 0,30,241:10:0:5,0:5,0:10,0 17 463 . G <*> 0 . DP=32;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1095,41573,0,0,1775,103851,0,0,583,12729,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,12,126:4:0:3,0:1,0:4,0 0,30,221:10:0:5,0:5,0:10,0 17 464 . A <*> 0 . DP=32;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1100,41724,0,0,1775,103851,0,0,589,12821,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,12,148:4:0:3,0:1,0:4,0 0,30,217:10:0:5,0:5,0:10,0 17 465 . C T,<*> 0 . DP=33;ADF=19,0,0;ADR=12,1,0;AD=31,1,0;I16=19,12,0,1,1173,45601,4,16,1775,103851,60,3600,589,12909,6,36;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.67982;MQBZ=0.321288;MQSBZ=0.341466;BQBZ=-1.68493;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255,51,255,255:17:0:10,0,0:7,0,0:17,0,0 0,15,158,15,158,158:5:0:4,0,0:1,0,0:5,0,0 0,20,224,27,227,224:10:0:5,0,0:4,1,0:9,1,0 17 466 . A <*> 0 . DP=34;ADF=20,0;ADR=13,0;AD=33,0;I16=20,13,0,0,1268,49686,0,0,1895,111051,0,0,602,13102,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,15,173:5:0:4,0:1,0:5,0 0,30,255:10:0:5,0:5,0:10,0 17 467 . A <*> 0 . DP=34;ADF=20,0;ADR=13,0;AD=33,0;I16=20,13,0,0,1246,48610,0,0,1895,111051,0,0,608,13194,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,15,177:5:0:4,0:1,0:5,0 0,30,251:10:0:5,0:5,0:10,0 17 468 . A <*> 0 . DP=35;ADF=21,0;ADR=13,0;AD=34,0;I16=21,13,0,0,1253,48095,0,0,1955,114651,0,0,613,13273,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,174:5:0:4,0:1,0:5,0 0,30,251:10:0:5,0:5,0:10,0 17 469 . A <*> 0 . DP=35;ADF=21,0;ADR=13,0;AD=34,0;I16=21,13,0,0,1260,49028,0,0,1955,114651,0,0,618,13340,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,165:5:0:4,0:1,0:5,0 0,30,255:10:0:5,0:5,0:10,0 17 470 . G <*> 0 . DP=35;ADF=21,0;ADR=13,0;AD=34,0;I16=21,13,0,0,1265,48879,0,0,1955,114651,0,0,623,13445,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,167:5:0:4,0:1,0:5,0 0,30,238:10:0:5,0:5,0:10,0 17 471 . T G,C,<*> 0 . DP=36;ADF=21,0,0,0;ADR=12,1,1,0;AD=33,1,1,0;I16=21,12,0,2,1220,46380,18,162,1918,113282,97,4969,611,13281,16,256;QS=2.94529,0.0273556,0.0273556,0;VDB=0.96;SGB=0.346553;RPBZ=0.497712;MQBZ=-1.9761;MQSBZ=0.312094;BQBZ=-2.35032;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255,57,255,255,57,255,255,255:19:0:12,0,0,0:7,0,0,0:19,0,0,0 0,15,169,15,169,169,15,169,169,169:5:0:4,0,0,0:1,0,0,0:5,0,0,0 0,19,219,19,221,219,27,222,222,221:11:3:5,0,0,0:4,1,1,0:9,1,1,0 17 472 . T <*> 0 . DP=35;ADF=21,0;ADR=13,0;AD=34,0;I16=21,13,0,0,1234,46640,0,0,1955,114651,0,0,633,13665,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,172:5:0:4,0:1,0:5,0 0,30,241:10:0:5,0:5,0:10,0 17 473 . G <*> 0 . DP=35;ADF=21,0;ADR=13,0;AD=34,0;I16=21,13,0,0,1303,51953,0,0,1955,114651,0,0,638,13780,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,159:5:0:4,0:1,0:5,0 0,30,250:10:0:5,0:5,0:10,0 17 474 . G <*> 0 . DP=36;ADF=22,0;ADR=13,0;AD=35,0;I16=22,13,0,0,1279,49235,0,0,2015,118251,0,0,642,13884,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,146:5:0:4,0:1,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 475 . G <*> 0 . DP=36;ADF=22,0;ADR=13,0;AD=35,0;I16=22,13,0,0,1299,49939,0,0,2015,118251,0,0,647,14029,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,159:5:0:4,0:1,0:5,0 0,33,253:11:0:6,0:5,0:11,0 17 476 . A <*> 0 . DP=36;ADF=22,0;ADR=13,0;AD=35,0;I16=22,13,0,0,1298,50202,0,0,2015,118251,0,0,651,14167,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,177:5:0:4,0:1,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 477 . T <*> 0 . DP=36;ADF=22,0;ADR=13,0;AD=35,0;I16=22,13,0,0,1301,50339,0,0,2015,118251,0,0,655,14349,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,167:5:0:4,0:1,0:5,0 0,33,255:11:0:6,0:5,0:11,0 17 478 . T <*> 0 . DP=38;ADF=24,0;ADR=13,0;AD=37,0;I16=24,13,0,0,1318,48974,0,0,2135,125451,0,0,656,14422,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:13,0:7,0:20,0 0,18,174:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 479 . A <*> 0 . DP=38;ADF=24,0;ADR=13,0;AD=37,0;I16=24,13,0,0,1397,54499,0,0,2135,125451,0,0,659,14535,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:13,0:7,0:20,0 0,18,184:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 480 . G <*> 0 . DP=37;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1419,57531,0,0,2075,121851,0,0,662,14638,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,18,187:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 481 . G <*> 0 . DP=37;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1382,54524,0,0,2075,121851,0,0,664,14728,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,18,187:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 482 . A <*> 0 . DP=37;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1344,52614,0,0,2075,121851,0,0,666,14854,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,18,164:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 483 . G <*> 0 . DP=37;ADF=23,0;ADR=13,0;AD=36,0;I16=23,13,0,0,1402,55722,0,0,2075,121851,0,0,666,14864,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,18,187:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 484 . A <*> 0 . DP=36;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1329,52551,0,0,2015,118251,0,0,668,14906,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,191:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 485 . G <*> 0 . DP=35;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,160:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 486 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1313,51667,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,173:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 487 . G <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1300,50304,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,169:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 488 . A G,<*> 0 . DP=35;ADF=22,1,0;ADR=12,0,0;AD=34,1,0;I16=22,12,1,0,1278,48412,4,16,1986,117410,29,841,646,14380,25,625;QS=2.98947,0.0105263,0;SGB=-0.556633;RPBZ=0.594463;MQBZ=-3.36505;MQSBZ=0.10737;BQBZ=-1.69552;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255,54,255,255:18:0:12,0,0:6,0,0:18,0,0 0,18,177,18,177,177:6:0:5,0,0:1,0,0:6,0,0 0,23,255,30,255,255:11:0:5,1,0:5,0,0:10,1,0 17 489 . A <*> 0 . DP=35;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,175:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 17 490 . A <*> 0 . DP=36;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,188:7:0:6,0:1,0:7,0 0,33,255:11:0:6,0:5,0:11,0 17 491 . T <*> 0 . DP=36;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,178:7:0:6,0:1,0:7,0 0,33,255:11:0:6,0:5,0:11,0 17 492 . G <*> 0 . DP=35;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1273,48547,0,0,2046,121010,0,0,671,15109,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,175:7:0:6,0:1,0:7,0 0,30,251:10:0:5,0:5,0:10,0 17 493 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1281,49545,0,0,1986,117410,0,0,672,15156,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,186:7:0:6,0:1,0:7,0 0,27,242:9:0:4,0:5,0:9,0 17 494 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1324,52440,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,195:7:0:6,0:1,0:7,0 0,27,255:9:0:4,0:5,0:9,0 17 495 . G <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1265,48677,0,0,1986,117410,0,0,672,15236,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,170:7:0:6,0:1,0:7,0 0,27,244:9:0:4,0:5,0:9,0 17 496 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,186:7:0:6,0:1,0:7,0 0,27,249:9:0:4,0:5,0:9,0 17 497 . C <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,164:7:0:6,0:1,0:7,0 0,27,239:9:0:4,0:5,0:9,0 17 498 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,185:7:0:6,0:1,0:7,0 0,27,252:9:0:4,0:5,0:9,0 17 499 . T <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,183:7:0:6,0:1,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 500 . A <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,179:7:0:6,0:1,0:7,0 0,30,255:10:0:5,0:5,0:10,0 17 501 . T <*> 0 . DP=33;ADF=23,0;ADR=10,0;AD=33,0;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,186:7:0:6,0:1,0:7,0 0,27,241:9:0:5,0:4,0:9,0 17 502 . G <*> 0 . DP=33;ADF=23,0;ADR=10,0;AD=33,0;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,183:7:0:6,0:1,0:7,0 0,27,235:9:0:5,0:4,0:9,0 17 503 . T <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,177:7:0:6,0:1,0:7,0 0,27,234:9:0:5,0:4,0:9,0 17 504 . C <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,183:7:0:6,0:1,0:7,0 0,27,219:9:0:5,0:4,0:9,0 17 505 . C <*> 0 . DP=35;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1217,44421,0,0,2046,121010,0,0,648,14558,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,189:7:0:6,0:1,0:7,0 0,27,221:9:0:5,0:4,0:9,0 17 506 . A <*> 0 . DP=35;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,188:7:0:6,0:1,0:7,0 0,27,231:9:0:5,0:4,0:9,0 17 507 . C <*> 0 . DP=35;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1231,45137,0,0,2046,121010,0,0,644,14482,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,183:7:0:6,0:1,0:7,0 0,27,226:9:0:5,0:4,0:9,0 17 508 . A <*> 0 . DP=34;ADF=24,0;ADR=10,0;AD=34,0;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,189:7:0:6,0:1,0:7,0 0,27,220:9:0:5,0:4,0:9,0 17 509 . C <*> 0 . DP=34;ADF=24,0;ADR=10,0;AD=34,0;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,186:7:0:6,0:1,0:7,0 0,27,241:9:0:5,0:4,0:9,0 17 510 . A <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1211,44827,0,0,1986,117410,0,0,638,14398,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,187:7:0:6,0:1,0:7,0 0,24,221:8:0:4,0:4,0:8,0 17 511 . A <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1238,46516,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,195:7:0:6,0:1,0:7,0 0,24,233:8:0:4,0:4,0:8,0 17 512 . A C,<*> 0 . DP=33;ADF=22,0,0;ADR=10,1,0;AD=32,1,0;I16=22,10,0,1,1133,41513,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97766,0.0223368,0;SGB=-0.556633;RPBZ=-1.47079;MQBZ=0.253876;MQSBZ=-0.461593;BQBZ=-1.68442;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255,51,255,255:18:0:12,0,0:5,1,0:17,1,0 0,21,183,21,183,183:7:0:6,0,0:1,0,0:7,0,0 0,24,231,24,231,231:8:0:4,0,0:4,0,0:8,0,0 17 513 . A T,<*> 0 . DP=32;ADF=21,1,0;ADR=10,0,0;AD=31,1,0;I16=21,10,1,0,1125,42283,12,144,1806,106610,60,3600,623,14249,15,225;QS=2.97966,0.020339,0;SGB=-0.556633;RPBZ=-1.24609;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.57376;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,37,255,48,255,255:17:0:11,1,0:5,0,0:16,1,0 0,21,177,21,177,177:7:0:6,0,0:1,0,0:7,0,0 0,24,233,24,233,233:8:0:4,0,0:4,0,0:8,0,0 17 514 . A T,<*> 0 . DP=32;ADF=22,0,0;ADR=9,1,0;AD=31,1,0;I16=22,9,0,1,1086,40204,16,256,1806,106610,60,3600,627,14381,11,121;QS=2.97127,0.0287253,0;SGB=-0.556633;RPBZ=-1.4628;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.46657;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,34,255,48,255,255:17:0:12,0,0:4,1,0:16,1,0 0,21,172,21,172,172:7:0:6,0,0:1,0,0:7,0,0 0,24,235,24,235,235:8:0:4,0,0:4,0,0:8,0,0 17 515 . C <*> 0 . DP=32;ADF=22,0;ADR=10,0;AD=32,0;I16=22,10,0,0,1050,37704,0,0,1866,110210,0,0,638,14554,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,169:7:0:6,0:1,0:7,0 0,24,211:8:0:4,0:4,0:8,0 17 516 . C <*> 0 . DP=32;ADF=22,0;ADR=10,0;AD=32,0;I16=22,10,0,0,1109,40651,0,0,1866,110210,0,0,637,14579,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,187:7:0:6,0:1,0:7,0 0,24,215:8:0:4,0:4,0:8,0 17 517 . T <*> 0 . DP=33;ADF=23,0;ADR=10,0;AD=33,0;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,201:7:0:6,0:1,0:7,0 0,24,242:8:0:4,0:4,0:8,0 17 518 . G <*> 0 . DP=34;ADF=24,0;ADR=10,0;AD=34,0;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,21,182:7:0:6,0:1,0:7,0 0,24,220:8:0:4,0:4,0:8,0 17 519 . T <*> 0 . DP=36;ADF=25,0;ADR=11,0;AD=36,0;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,63,255:21:0:15,0:6,0:21,0 0,21,177:7:0:6,0:1,0:7,0 0,24,224:8:0:4,0:4,0:8,0 17 520 . T <*> 0 . DP=36;ADF=25,0;ADR=11,0;AD=36,0;I16=25,11,0,0,1243,45051,0,0,2106,124610,0,0,638,14818,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,63,255:21:0:15,0:6,0:21,0 0,21,180:7:0:6,0:1,0:7,0 0,24,223:8:0:4,0:4,0:8,0 17 521 . C <*> 0 . DP=34;ADF=25,0;ADR=9,0;AD=34,0;I16=25,9,0,0,1281,49527,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,191:7:0:6,0:1,0:7,0 0,21,204:7:0:4,0:3,0:7,0 17 522 . A <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,185:7:0:6,0:1,0:7,0 0,15,170:5:0:3,0:2,0:5,0 17 523 . T G,<*> 0 . DP=32;ADF=23,1,0;ADR=8,0,0;AD=31,1,0;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPBZ=1.13742;MQBZ=0.179605;MQSBZ=-1.73205;BQBZ=-1.68805;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,44,255,57,255,255:20:0:14,1,0:5,0,0:19,1,0 0,21,191,21,191,191:7:0:6,0,0:1,0,0:7,0,0 0,15,166,15,166,166:5:0:3,0,0:2,0,0:5,0,0 17 524 . T <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1096,39618,0,0,1897,112969,0,0,654,15108,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,194:7:0:6,0:1,0:7,0 0,15,150:5:0:3,0:2,0:5,0 17 525 . G <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1188,45718,0,0,1897,112969,0,0,656,15120,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,188:7:0:6,0:1,0:7,0 0,15,133:5:0:3,0:2,0:5,0 17 526 . C <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1154,44014,0,0,1897,112969,0,0,658,15156,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,185:7:0:6,0:1,0:7,0 0,15,137:5:0:3,0:2,0:5,0 17 527 . A <*> 0 . DP=33;ADF=25,0;ADR=8,0;AD=33,0;I16=25,8,0,0,1220,46386,0,0,1957,116569,0,0,658,15118,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,194:7:0:6,0:1,0:7,0 0,18,181:6:0:4,0:2,0:6,0 17 528 . G <*> 0 . DP=33;ADF=25,0;ADR=8,0;AD=33,0;I16=25,8,0,0,1268,49968,0,0,1957,116569,0,0,658,15060,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,172:7:0:6,0:1,0:7,0 0,18,193:6:0:4,0:2,0:6,0 17 529 . C <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1158,44462,0,0,1897,112969,0,0,658,14982,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,187:7:0:6,0:1,0:7,0 0,18,184:6:0:4,0:2,0:6,0 17 530 . T <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,196:7:0:6,0:1,0:7,0 0,18,202:6:0:4,0:2,0:6,0 17 531 . T <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,181:7:0:6,0:1,0:7,0 0,18,193:6:0:4,0:2,0:6,0 17 532 . T <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1161,43607,0,0,1897,112969,0,0,649,14477,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,181:7:0:6,0:1,0:7,0 0,18,192:6:0:4,0:2,0:6,0 17 533 . C <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1154,44084,0,0,1897,112969,0,0,644,14274,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,178:7:0:6,0:1,0:7,0 0,18,180:6:0:4,0:2,0:6,0 17 534 . T <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1222,49526,0,0,1837,109369,0,0,640,14104,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,205:7:0:6,0:1,0:7,0 0,18,205:6:0:4,0:2,0:6,0 17 535 . A G,<*> 0 . DP=31;ADF=24,0,0;ADR=6,1,0;AD=30,1,0;I16=24,6,0,1,1080,39870,8,64,1777,105769,60,3600,611,13341,25,625;QS=2.98623,0.0137694,0;SGB=-0.556633;RPBZ=-0.894788;MQBZ=0.182574;MQSBZ=-1.85164;BQBZ=-1.6854;SCBZ=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,41,255,51,255,255:18:0:14,0,0:3,1,0:17,1,0 0,21,194,21,194,194:7:0:6,0,0:1,0,0:7,0,0 0,18,189,18,189,189:6:0:4,0,0:2,0,0:6,0,0 17 536 . C <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1095,40551,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,184:7:0:6,0:1,0:7,0 0,18,157:6:0:4,0:2,0:6,0 17 537 . C <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1049,38677,0,0,1837,109369,0,0,626,13682,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,172:7:0:6,0:1,0:7,0 0,18,183:6:0:4,0:2,0:6,0 17 538 . A <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,189:7:0:6,0:1,0:7,0 0,18,181:6:0:4,0:2,0:6,0 17 539 . T <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,178:7:0:6,0:1,0:7,0 0,18,181:6:0:4,0:2,0:6,0 17 540 . C <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,177:7:0:6,0:1,0:7,0 0,18,178:6:0:4,0:2,0:6,0 17 541 . A <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1100,40408,0,0,1897,112969,0,0,601,13241,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,24,180:8:0:7,0:1,0:8,0 0,18,159:6:0:4,0:2,0:6,0 17 542 . C <*> 0 . DP=33;ADF=25,0;ADR=8,0;AD=33,0;I16=25,8,0,0,1130,41788,0,0,1926,113810,0,0,608,13346,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,27,176:9:0:7,0:2,0:9,0 0,18,174:6:0:4,0:2,0:6,0 17 543 . C <*> 0 . DP=34;ADF=25,0;ADR=9,0;AD=34,0;I16=25,9,0,0,1211,45383,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,27,194:9:0:7,0:2,0:9,0 0,18,188:6:0:4,0:2,0:6,0 17 544 . A <*> 0 . DP=33;ADF=25,0;ADR=8,0;AD=33,0;I16=25,8,0,0,1205,45463,0,0,1926,113810,0,0,595,13131,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,24,198:8:0:7,0:1,0:8,0 0,18,180:6:0:4,0:2,0:6,0 17 545 . A <*> 0 . DP=33;ADF=25,0;ADR=8,0;AD=33,0;I16=25,8,0,0,1197,44795,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,24,196:8:0:7,0:1,0:8,0 0,18,184:6:0:4,0:2,0:6,0 17 546 . A <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1136,41758,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,21,166:7:0:6,0:1,0:7,0 0,18,193:6:0:4,0:2,0:6,0 17 547 . A <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1159,43539,0,0,1866,110210,0,0,572,12634,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,21,180:7:0:6,0:1,0:7,0 0,18,195:6:0:4,0:2,0:6,0 17 548 . A C,<*> 0 . DP=33;ADF=23,1,0;ADR=9,0,0;AD=32,1,0;I16=23,9,1,0,1153,42673,9,81,1866,110210,60,3600,561,12489,3,9;QS=2.98607,0.0139319,0;SGB=-0.556633;RPBZ=1.57584;MQBZ=0.253876;MQSBZ=-2.34521;BQBZ=-1.68939;SCBZ=3.80814;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,44,255,54,255,255:19:0:13,1,0:5,0,0:18,1,0 0,21,181,21,181,181:7:0:6,0,0:1,0,0:7,0,0 0,21,211,21,211,211:7:0:4,0,0:3,0,0:7,0,0 17 549 . T G,<*> 0 . DP=32;ADF=23,0,0;ADR=8,1,0;AD=31,1,0;I16=23,8,0,1,1135,42143,20,400,1806,106610,60,3600,532,11720,25,625;QS=2.96918,0.0308166,0;SGB=-0.556633;RPBZ=-0.487556;MQBZ=0.258065;MQSBZ=-2.29695;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,34,255,51,255,255:18:0:13,0,0:4,1,0:17,1,0 0,21,168,21,168,168:7:0:6,0,0:1,0,0:7,0,0 0,21,208,21,208,208:7:0:4,0,0:3,0,0:7,0,0 17 550 . T <*> 0 . DP=32;ADF=23,0;ADR=9,0;AD=32,0;I16=23,9,0,0,1056,37314,0,0,1866,110210,0,0,549,12177,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,150:7:0:6,0:1,0:7,0 0,21,220:7:0:4,0:3,0:7,0 17 551 . G <*> 0 . DP=31;ADF=22,0;ADR=9,0;AD=31,0;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,172:7:0:6,0:1,0:7,0 0,21,208:7:0:4,0:3,0:7,0 17 552 . C <*> 0 . DP=30;ADF=21,0;ADR=9,0;AD=30,0;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:11,0:5,0:16,0 0,21,167:7:0:6,0:1,0:7,0 0,21,208:7:0:4,0:3,0:7,0 17 553 . A <*> 0 . DP=30;ADF=21,0;ADR=9,0;AD=30,0;I16=21,9,0,0,1006,36136,0,0,1746,103010,0,0,528,11780,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:11,0:5,0:16,0 0,18,150:6:0:5,0:1,0:6,0 0,24,203:8:0:5,0:3,0:8,0 17 554 . A <*> 0 . DP=30;ADF=21,0;ADR=9,0;AD=30,0;I16=21,9,0,0,1008,36694,0,0,1746,103010,0,0,521,11595,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:11,0:5,0:16,0 0,18,143:6:0:5,0:1,0:6,0 0,24,221:8:0:5,0:3,0:8,0 17 555 . A <*> 0 . DP=30;ADF=20,0;ADR=10,0;AD=30,0;I16=20,10,0,0,1022,36374,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,150:6:0:5,0:1,0:6,0 0,21,211:7:0:4,0:3,0:7,0 17 556 . C <*> 0 . DP=29;ADF=20,0;ADR=9,0;AD=29,0;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,158:6:0:5,0:1,0:6,0 0,18,186:6:0:4,0:2,0:6,0 17 557 . A <*> 0 . DP=27;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,157:6:0:5,0:1,0:6,0 0,18,186:6:0:4,0:2,0:6,0 17 558 . A <*> 0 . DP=27;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,956,35872,0,0,1589,94441,0,0,502,10906,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,153:6:0:5,0:1,0:6,0 0,18,177:6:0:4,0:2,0:6,0 17 559 . C A,<*> 0 . DP=27;ADF=18,0,0;ADR=8,1,0;AD=26,1,0;I16=18,8,0,1,915,33775,14,196,1560,93600,29,841,473,10141,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPBZ=-1.02726;MQBZ=-5.09902;MQSBZ=-1.41421;BQBZ=-1.54776;SCBZ=5.09902;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255,45,255,255:15:0:9,0,0:6,0,0:15,0,0 0,4,116,15,119,123:6:0:5,0,0:0,1,0:5,1,0 0,18,169,18,169,169:6:0:4,0,0:2,0,0:6,0,0 17 560 . C <*> 0 . DP=28;ADF=19,0;ADR=9,0;AD=28,0;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,160:6:0:5,0:1,0:6,0 0,21,181:7:0:5,0:2,0:7,0 17 561 . A <*> 0 . DP=28;ADF=19,0;ADR=9,0;AD=28,0;I16=19,9,0,0,973,35555,0,0,1649,98041,0,0,491,10571,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,158:6:0:5,0:1,0:6,0 0,21,194:7:0:5,0:2,0:7,0 17 562 . C <*> 0 . DP=28;ADF=19,0;ADR=9,0;AD=28,0;I16=19,9,0,0,1014,38392,0,0,1649,98041,0,0,488,10518,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,153:6:0:5,0:1,0:6,0 0,21,187:7:0:5,0:2,0:7,0 17 563 . A <*> 0 . DP=27;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,903,32513,0,0,1589,94441,0,0,485,10445,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,15,149:5:0:4,0:1,0:5,0 0,21,179:7:0:5,0:2,0:7,0 17 564 . C <*> 0 . DP=27;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,15,121:5:0:4,0:1,0:5,0 0,21,182:7:0:5,0:2,0:7,0 17 565 . G <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,842,27104,0,0,1769,105241,0,0,479,10389,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,18,100:6:0:4,0:2,0:6,0 0,21,154:7:0:5,0:2,0:7,0 17 566 . C A,<*> 0 . DP=29;ADF=16,1,0;ADR=12,0,0;AD=28,1,0;I16=16,12,1,0,920,33998,9,81,1649,98041,60,3600,454,9734,25,625;QS=2.98321,0.016791,0;SGB=-0.556633;RPBZ=0.239193;MQBZ=0.188982;MQSBZ=-1.19024;BQBZ=-1.43942;SCBZ=-0.188982;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,38,255,48,255,255:17:0:8,1,0:8,0,0:16,1,0 0,15,155,15,155,155:5:0:3,0,0:2,0,0:5,0,0 0,21,170,21,170,170:7:0:5,0,0:2,0,0:7,0,0 17 567 . C <*> 0 . DP=30;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,956,34312,0,0,1769,105241,0,0,496,10638,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,18,156:6:0:3,0:3,0:6,0 0,21,194:7:0:5,0:2,0:7,0 17 568 . C <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1060,40304,0,0,1709,101641,0,0,497,10663,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,18,179:6:0:3,0:3,0:6,0 0,21,193:7:0:5,0:2,0:7,0 17 569 . T <*> 0 . DP=30;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1061,41321,0,0,1709,101641,0,0,497,10671,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,18,190:6:0:3,0:3,0:6,0 0,21,213:7:0:5,0:2,0:7,0 17 570 . T <*> 0 . DP=30;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,962,34938,0,0,1709,101641,0,0,497,10711,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,18,162:6:0:3,0:3,0:6,0 0,21,195:7:0:5,0:2,0:7,0 17 571 . C <*> 0 . DP=31;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1069,40739,0,0,1769,105241,0,0,497,10783,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,18,159:6:0:3,0:3,0:6,0 0,21,193:7:0:5,0:2,0:7,0 17 572 . A <*> 0 . DP=31;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1092,41268,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,21,204:7:0:4,0:3,0:7,0 0,18,175:6:0:5,0:1,0:6,0 17 573 . A <*> 0 . DP=31;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1060,38698,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,21,201:7:0:4,0:3,0:7,0 0,18,178:6:0:5,0:1,0:6,0 17 574 . C A,<*> 0 . DP=31;ADF=18,0,0;ADR=11,1,0;AD=29,1,0;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPBZ=-0.173514;MQBZ=-5.38516;MQSBZ=-1.22474;BQBZ=-1.68578;SCBZ=3.60588;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255,48,255,255:16:0:8,0,0:8,0,0:16,0,0 0,9,170,21,173,177:8:0:5,0,0:2,1,0:7,1,0 0,18,173,18,173,173:6:0:5,0,0:1,0,0:6,0,0 17 575 . T C,<*> 0 . DP=30;ADF=17,0,0;ADR=11,1,0;AD=28,1,0;I16=17,11,0,1,1048,41548,9,81,1680,100800,29,841,480,10426,25,625;QS=2.96786,0.0321429,0;SGB=-0.556633;RPBZ=-0.119685;MQBZ=-5.2915;MQSBZ=-1.19024;BQBZ=-1.68121;SCBZ=3.53589;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255,48,255,255:16:0:8,0,0:8,0,0:16,0,0 0,13,200,21,203,202:8:0:5,0,0:2,1,0:7,1,0 0,15,163,15,163,163:5:0:4,0,0:1,0,0:5,0,0 17 576 . G <*> 0 . DP=30;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1043,39581,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,24,208:8:0:5,0:3,0:8,0 0,15,151:5:0:4,0:1,0:5,0 17 577 . G <*> 0 . DP=30;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,997,37255,0,0,1709,101641,0,0,509,11155,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,24,204:8:0:5,0:3,0:8,0 0,15,146:5:0:4,0:1,0:5,0 17 578 . G <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:7,0:9,0:16,0 0,24,198:8:0:5,0:3,0:8,0 0,15,151:5:0:4,0:1,0:5,0 17 579 . G <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1038,38820,0,0,1769,105241,0,0,523,11335,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,24,224:8:0:4,0:4,0:8,0 0,15,144:5:0:4,0:1,0:5,0 17 580 . A C,<*> 0 . DP=30;ADF=15,1,0;ADR=14,0,0;AD=29,1,0;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPBZ=1.32953;MQBZ=0.185695;MQSBZ=-1.06904;BQBZ=-1.69093;SCBZ=-0.267102;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,34,255,48,255,255:17:0:7,1,0:9,0,0:16,1,0 0,24,221,24,221,221:8:0:4,0,0:4,0,0:8,0,0 0,15,155,15,155,155:5:0:4,0,0:1,0,0:5,0,0 17 581 . A <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:8,0:10,0:18,0 0,24,223:8:0:4,0:4,0:8,0 0,15,153:5:0:4,0:1,0:5,0 17 582 . C G,<*> 0 . DP=31;ADF=15,1,0;ADR=15,0,0;AD=30,1,0;I16=15,15,1,0,1080,39870,8,64,1769,105241,60,3600,519,11211,15,225;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.34259;MQBZ=0.182574;MQSBZ=-1.0328;BQBZ=-1.68266;SCBZ=-0.262467;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,41,255,51,255,255:18:0:7,1,0:10,0,0:17,1,0 0,24,207,24,207,207:8:0:4,0,0:4,0,0:8,0,0 0,15,151,15,151,151:5:0:4,0,0:1,0,0:5,0,0 17 583 . T <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1135,43913,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,24,238:8:0:4,0:4,0:8,0 0,15,163:5:0:4,0:1,0:5,0 17 584 . C <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1069,39521,0,0,1798,106082,0,0,544,11644,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,209:8:0:4,0:4,0:8,0 0,15,157:5:0:4,0:1,0:5,0 17 585 . A <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,211:8:0:4,0:4,0:8,0 0,15,157:5:0:4,0:1,0:5,0 17 586 . T <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1091,39939,0,0,1798,106082,0,0,553,11845,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,212:8:0:4,0:4,0:8,0 0,15,156:5:0:4,0:1,0:5,0 17 587 . C <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1078,39466,0,0,1798,106082,0,0,557,11975,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,204:8:0:4,0:4,0:8,0 0,15,155:5:0:4,0:1,0:5,0 17 588 . A <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,222:8:0:4,0:4,0:8,0 0,15,164:5:0:4,0:1,0:5,0 17 589 . A <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1156,43908,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,235:8:0:4,0:4,0:8,0 0,15,165:5:0:4,0:1,0:5,0 17 590 . C <*> 0 . DP=32;ADF=17,0;ADR=15,0;AD=32,0;I16=17,15,0,0,1103,41355,0,0,1858,109682,0,0,574,12576,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,194:8:0:4,0:4,0:8,0 0,18,175:6:0:4,0:2,0:6,0 17 591 . A <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1164,44088,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,209:7:0:3,0:4,0:7,0 0,18,188:6:0:4,0:2,0:6,0 17 592 . A <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1121,42193,0,0,1798,106082,0,0,583,12795,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,215:7:0:3,0:4,0:7,0 0,18,182:6:0:4,0:2,0:6,0 17 593 . C A,<*> 0 . DP=31;ADF=16,0,0;ADR=14,1,0;AD=30,1,0;I16=16,14,0,1,1071,39925,7,49,1769,105241,29,841,561,12253,25,625;QS=2.97021,0.0297872,0;SGB=-0.556633;RPBZ=0.559355;MQBZ=-3.80789;MQSBZ=-0.0464238;BQBZ=-1.57464;SCBZ=3.67454;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255,54,255,255:18:0:9,0,0:9,0,0:18,0,0 0,12,184,18,187,185:7:0:3,0,0:3,1,0:6,1,0 0,18,174,18,174,174:6:0:4,0,0:2,0,0:6,0,0 17 594 . A G,<*> 0 . DP=33;ADF=16,1,0;ADR=16,0,0;AD=32,1,0;I16=16,16,1,0,1161,42757,4,16,1858,109682,60,3600,572,12672,15,225;QS=2.99359,0.00641026,0;SGB=-0.556633;RPBZ=-0.998367;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68954;SCBZ=-0.253876;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255,51,255,255:18:0:8,1,0:9,0,0:17,1,0 0,21,205,21,205,205:7:0:3,0,0:4,0,0:7,0,0 0,24,213,24,213,213:8:0:5,0,0:3,0,0:8,0,0 17 595 . A <*> 0 . DP=33;ADF=17,0;ADR=16,0;AD=33,0;I16=17,16,0,0,1136,40412,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,198:7:0:3,0:4,0:7,0 0,24,218:8:0:5,0:3,0:8,0 17 596 . A G,<*> 0 . DP=33;ADF=16,1,0;ADR=16,0,0;AD=32,1,0;I16=16,16,1,0,1061,37187,8,64,1858,109682,60,3600,590,12952,1,1;QS=2.98564,0.0143627,0;SGB=-0.556633;RPBZ=1.68146;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68357;SCBZ=-0.253876;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,41,255,51,255,255:18:0:8,1,0:9,0,0:17,1,0 0,21,169,21,169,169:7:0:3,0,0:4,0,0:7,0,0 0,24,231,24,231,231:8:0:5,0,0:3,0,0:8,0,0 17 597 . C <*> 0 . DP=33;ADF=17,0;ADR=16,0;AD=33,0;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,204:7:0:3,0:4,0:7,0 0,24,220:8:0:5,0:3,0:8,0 17 598 . T <*> 0 . DP=33;ADF=16,0;ADR=17,0;AD=33,0;I16=16,17,0,0,1219,47333,0,0,1918,113282,0,0,597,13029,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,217:7:0:3,0:4,0:7,0 0,27,242:9:0:5,0:4,0:9,0 17 599 . T <*> 0 . DP=33;ADF=16,0;ADR=17,0;AD=33,0;I16=16,17,0,0,1182,43598,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,197:7:0:3,0:4,0:7,0 0,27,247:9:0:5,0:4,0:9,0 17 600 . G <*> 0 . DP=32;ADF=15,0;ADR=17,0;AD=32,0;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,194:7:0:3,0:4,0:7,0 0,24,232:8:0:4,0:4,0:8,0 bcftools-1.21/test/mpileup/mpileup.6.out000066400000000000000000000465011467060157400202720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 17 100 . C <*> . . END=102;MIN_DP=3;QS=3,0 PL:DP 0,27,182:9 0,9,108:3 0,15,132:5 17 103 . T C,<*> 0 . DP=18;I16=15,1,1,0,668,28542,6,36,929,54841,29,841,323,7035,6,36;QS=2.98256,0.0174419,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64924;SCBZ=4;MQ0F=0 PL:DP:DV 0,17,184,24,187,185:9:1 0,9,118,9,118,118:3:0 0,15,147,15,147,147:5:0 17 104 . G C,<*> 0 . DP=18;I16=15,1,1,0,601,24163,3,9,929,54841,29,841,320,6884,7,49;QS=2.98726,0.0127389,0;SGB=-0.556633;RPBZ=-1.02125;MQBZ=-2.73861;MQSBZ=0.365148;BQBZ=-1.64309;SCBZ=4;MQ0F=0 PL:DP:DV 0,18,173,24,176,173:9:1 0,9,101,9,101,101:3:0 0,15,133,15,133,133:5:0 17 105 . G <*> . . END=108;MIN_DP=3;QS=3,0 PL:DP 0,30,171:10 0,9,92:3 0,15,124:5 17 109 . T C,<*> 0 . DP=19;I16=16,1,1,0,716,30648,2,4,989,58441,29,841,309,6415,12,144;QS=2.98922,0.0107817,0;SGB=-0.556633;RPBZ=-0.674966;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.6661;SCBZ=3;MQ0F=0 PL:DP:DV 0,20,191,27,194,191:10:1 0,9,120,9,120,120:3:0 0,15,150,15,150,150:5:0 17 110 . G <*> . . END=111;MIN_DP=3;QS=3,0 PL:DP 0,30,167:10 0,9,95:3 0,15,119:5 17 112 . C G,<*> 0 . DP=19;I16=16,1,1,0,657,26565,2,4,989,58441,29,841,301,6277,15,225;QS=2.98907,0.010929,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65292;SCBZ=3;MQ0F=0 PL:DP:DV 0,20,187,27,190,187:10:1 0,9,103,9,103,103:3:0 0,15,135,15,135,135:5:0 17 113 . A G,<*> 0 . DP=19;I16=16,1,1,0,635,25055,4,16,989,58441,29,841,297,6207,16,256;QS=2.98817,0.0118343,0;SGB=-0.556633;RPBZ=-0.482118;MQBZ=-2.82843;MQSBZ=0.353553;BQBZ=-1.65205;SCBZ=3;MQ0F=0 PL:DP:DV 0,20,172,27,175,172:10:1 0,9,102,9,102,102:3:0 0,15,139,15,139,139:5:0 17 114 . C <*> . . MIN_DP=3;QS=3,0 PL:DP 0,30,181:10 0,9,113:3 0,15,133:5 17 115 . C A,<*> 0 . DP=21;I16=17,2,1,0,688,27426,12,144,1078,62882,29,841,283,5827,25,625;QS=2.88785,0.11215,0;SGB=-0.556633;RPBZ=0.260329;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.47798;SCBZ=-0.418446;MQ0F=0 PL:DP:DV 0,30,189,30,189,189:10:0 3,0,86,9,89,93:3:1 0,21,153,21,153,153:7:0 17 116 . A C,<*> 0 . DP=21;I16=17,2,1,0,705,27791,2,4,1078,62882,29,841,287,6073,19,361;QS=2.98873,0.0112676,0;SGB=-0.556633;RPBZ=0.0867763;MQBZ=-2.38048;MQSBZ=-1.42419;BQBZ=-1.65814;SCBZ=2.65016;MQ0F=0 PL:DP:DV 0,20,179,27,182,179:10:1 0,9,102,9,102,102:3:0 0,21,175,21,175,175:7:0 17 117 . G <*> . . END=119;MIN_DP=2;QS=3,0 PL:DP 0,27,175:9 0,6,76:2 0,21,160:7 17 120 . A G,<*> 0 . DP=19;I16=15,2,1,0,646,25392,4,16,958,55682,29,841,277,5999,23,529;QS=2.9873,0.0126984,0;SGB=-0.556633;RPBZ=0.28942;MQBZ=-2.23607;MQSBZ=-1.30384;BQBZ=-1.6486;SCBZ=3;MQ0F=0 PL:DP:DV 0,18,171,24,174,171:9:1 0,6,88,6,88,88:2:0 0,21,171,21,171,171:7:0 17 121 . G <*> . . END=124;MIN_DP=2;QS=3,0 PL:DP 0,24,170:8 0,6,84:2 0,18,154:6 17 125 . A T,<*> 0 . DP=18;I16=14,2,1,0,589,22565,4,16,898,52082,29,841,272,5916,25,625;QS=2.98444,0.0155642,0;SGB=-0.556633;RPBZ=1.02125;MQBZ=-2.16025;MQSBZ=-1.23956;BQBZ=-1.64106;SCBZ=2.91548;MQ0F=0 PL:DP:DV 0,15,149,21,152,149:8:1 0,9,114,9,114,114:3:0 0,18,162,18,162,162:6:0 17 126 . A <*> . . END=158;MIN_DP=2;QS=3,0 PL:DP 0,18,128:6 0,6,81:2 0,15,102:5 17 159 . A G,<*> 0 . DP=15;I16=12,2,1,0,519,19467,5,25,809,47641,60,3600,260,5880,0,0;QS=2.97076,0.0292398,0;SGB=-0.556633;RPBZ=-1.62019;MQBZ=0.267261;MQSBZ=-2.54951;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:DV 0,21,157,21,157,157:7:0 0,6,83,6,83,83:2:0 0,10,129,15,132,129:6:1 17 160 . G <*> . . END=173;MIN_DP=2;QS=3,0 PL:DP 0,15,106:5 0,6,75:2 0,15,138:5 17 174 . G <*> . . END=188;MIN_DP=1;QS=3,0 PL:DP 0,15,111:5 0,3,27:1 0,21,116:7 17 189 . C <*> . . MIN_DP=2;QS=3,0 PL:DP 0,18,152:6 0,6,67:2 0,21,167:7 17 190 . A C,<*> 0 . DP=15;I16=12,2,1,0,500,18230,5,25,778,44882,60,3600,243,5381,25,625;QS=2.97664,0.0233645,0;SGB=-0.556633;RPBZ=0;MQBZ=0.392232;MQSBZ=-3.74166;BQBZ=-1.63041;SCBZ=0;MQ0F=0 PL:DP:DV 0,18,138,18,138,138:6:0 0,6,68,6,68,68:2:0 0,12,153,18,156,153:7:1 17 191 . T <*> . . END=222;MIN_DP=2;QS=3,0 PL:DP 0,18,140:6 0,6,63:2 0,12,73:4 17 223 . G T,<*> 0 . DP=13;I16=9,3,1,0,412,14782,8,64,627,34923,60,3600,243,5657,25,625;QS=2.96596,0.0340426,0;SGB=-0.556633;RPBZ=1.07052;MQBZ=0.547723;MQSBZ=-3.4641;BQBZ=-1.60577;SCBZ=0;MQ0F=0 PL:DP:DV 0,11,166,18,169,167:7:1 0,6,53,6,53,53:2:0 0,12,81,12,81,81:4:0 17 224 . G <*> . . END=225;MIN_DP=2;QS=3,0 PL:DP 0,18,165:6 0,6,48:2 0,12,70:4 17 226 . A G,C,<*> 0 . DP=13;I16=8,3,1,1,381,13669,6,18,567,31323,89,4441,248,5894,44,986;QS=2.94293,0.0392157,0.0178571,0;VDB=0.84;SGB=-2.62246;RPBZ=-0.592157;MQBZ=-0.615457;MQSBZ=-3.4641;BQBZ=-2.17723;SCBZ=2.34521;MQ0F=0 PL:DP:DV 0,18,159,12,162,159,18,159,162,159:7:1 0,6,53,6,53,53,6,53,53,53:2:0 0,5,79,9,82,80,9,82,80,80:4:1 17 227 . C <*> . . END=236;MIN_DP=2;QS=3,0 PL:DP 0,21,145:7 0,6,45:2 0,12,70:4 17 237 . A C,<*> 0 . DP=14;I16=9,4,1,0,465,16877,8,64,656,35764,60,3600,266,6282,25,625;QS=2.93162,0.0683761,0;SGB=-0.556633;RPBZ=1.11754;MQBZ=0.632456;MQSBZ=-3.60555;BQBZ=-1.61959;SCBZ=-0.27735;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,53,6,53,53:2:0 0,3,84,9,87,87:4:1 17 238 . C <*> . . END=255;MIN_DP=2;QS=3,0 PL:DP 0,24,211:8 0,6,50:2 0,12,64:4 17 256 . A <*> . . END=266;MIN_DP=5;QS=3,0 PL:DP 0,33,247:11 0,15,92:5 0,15,122:5 17 267 . T G,<*> 0 . DP=21;I16=9,11,0,1,739,27465,8,64,960,50456,29,841,373,7935,25,625;QS=2.94203,0.057971,0;SGB=-0.556633;RPBZ=-0.330396;MQBZ=-1.23153;MQSBZ=-3.3021;BQBZ=-1.66282;SCBZ=2.91633;MQ0F=0 PL:DP:DV 0,33,254,33,254,254:11:0 0,6,93,12,96,96:5:1 0,15,149,15,149,149:5:0 17 268 . T <*> . . END=272;MIN_DP=5;QS=3,0 PL:DP 0,33,238:11 0,15,91:5 0,15,143:5 17 273 . T C,<*> 0 . DP=22;I16=9,12,0,1,798,30664,5,25,989,51297,29,841,392,8620,25,625;QS=2.96094,0.0390625,0;SGB=-0.556633;RPBZ=-0.236567;MQBZ=-1.16701;MQSBZ=-3.42286;BQBZ=-1.66779;SCBZ=3.00076;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,7,89,12,92,90:5:1 0,15,161,15,161,161:5:0 17 274 . C <*> . . MIN_DP=5;QS=3,0 PL:DP 0,36,255:12 0,15,101:5 0,15,144:5 17 275 . C <*> . . END=277;MIN_DP=4;QS=3,0 PL:DP 0,33,253:11 0,15,114:5 0,12,121:4 17 278 . A C,<*> 0 . DP=21;I16=6,14,1,0,722,26452,7,49,867,42179,60,3600,415,9521,11,121;QS=2.97935,0.020649,0;SGB=-0.556633;RPBZ=1.65198;MQBZ=1.0247;MQSBZ=-3.24037;BQBZ=-1.66667;SCBZ=-0.324037;MQ0F=0 PL:DP:DV 0,22,231,30,234,231:11:1 0,18,123,18,123,123:6:0 0,12,121,12,121,121:4:0 17 279 . A <*> . . END=282;MIN_DP=4;QS=3,0 PL:DP 0,36,253:12 0,18,122:6 0,12,119:4 17 283 . C <*> . . END=296;MIN_DP=5;QS=3,0 PL:DP 0,33,240:11 0,18,119:6 0,15,122:5 17 297 . C G,<*> 0 . DP=25;I16=9,15,1,0,901,34305,4,16,1138,59338,60,3600,445,9901,10,100;QS=2.98261,0.0173913,0;SGB=-0.556633;RPBZ=-1.24856;MQBZ=0.806872;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.368383;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 0,15,168,21,171,168:8:1 0,18,161,18,161,161:6:0 17 298 . A <*> . . END=301;MIN_DP=7;QS=3,0 PL:DP 0,30,231:10 0,21,172:7 0,21,189:7 17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,240,9600,760,30400,236,10564,993,55133,109,2229,377,8629;QS=0.539485,2.46052;VDB=0.241622;SGB=-4.22417;RPBZ=1.11989;MQBZ=1.47646;MQSBZ=-3.22749;BQBZ=-1.67542;SCBZ=-0.268121;MQ0F=0 PL:DP:DV 161,0,99:11:6 158,0,14:7:6 201,21,0:7:7 17 303 . G <*> . . END=334;MIN_DP=7;QS=3,0 PL:DP 0,30,235:10 0,21,197:7 0,21,195:7 17 335 . A G,<*> 0 . DP=32;I16=13,18,1,0,1084,40336,4,16,1589,87297,60,3600,555,11943,0,0;QS=2.98919,0.0108108,0;SGB=-0.556633;RPBZ=-1.67936;MQBZ=0.622171;MQSBZ=-2.25492;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:DV 0,33,252,33,252,252:11:0 0,27,219,27,219,219:9:0 0,25,245,33,248,245:12:1 17 336 . A <*> . . MIN_DP=9;QS=3,0 PL:DP 0,33,255:11 0,27,212:9 0,36,255:12 17 337 . C A,<*> 0 . DP=32;I16=14,17,0,1,1125,42481,5,25,1612,89528,37,1369,536,11590,18,324;QS=2.98113,0.0188679,0;SGB=-0.556633;RPBZ=0.812593;MQBZ=-1.03695;MQSBZ=-2.25492;BQBZ=-1.68353;SCBZ=-0.258065;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 0,17,195,24,198,195:9:1 0,36,255,36,255,255:12:0 17 338 . T <*> . . END=354;MIN_DP=8;QS=3,0 PL:DP 0,27,225:9 0,24,185:8 0,30,255:10 17 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPBZ=0.185772;MQBZ=0.520126;MQSBZ=-1.7696;BQBZ=0.683978;SCBZ=-0.27735;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 17 356 . G <*> . . END=358;MIN_DP=8;QS=3,0 PL:DP 0,27,228:9 0,24,197:8 0,30,252:10 17 359 . G T,<*> 0 . DP=29;I16=15,13,0,1,1085,42761,10,100,1525,87005,60,3600,552,12620,25,625;QS=2.96032,0.0396825,0;SGB=-0.556633;RPBZ=-0.119611;MQBZ=0.456435;MQSBZ=-1.53333;BQBZ=-1.68246;SCBZ=5.2915;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,13,178,21,181,180:8:1 0,33,255,33,255,255:11:0 17 360 . A <*> . . END=368;MIN_DP=8;QS=3,0 PL:DP 0,30,252:10 0,24,204:8 0,30,255:10 17 369 . T G,<*> 0 . DP=28;I16=16,11,0,1,1037,40275,6,36,1496,86164,60,3600,548,12256,25,625;QS=2.97683,0.023166,0;SGB=-0.556633;RPBZ=0.12395;MQBZ=0.408248;MQSBZ=-1.37784;BQBZ=-1.68703;SCBZ=5.19615;MQ0F=0 PL:DP:DV 0,30,250,30,250,250:10:0 0,15,189,21,192,190:8:1 0,30,255,30,255,255:10:0 17 370 . C <*> . . END=374;MIN_DP=8;QS=3,0 PL:DP 0,30,255:10 0,24,201:8 0,30,255:10 17 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPBZ=-1.45432;MQBZ=0.3849;MQSBZ=-1.26404;BQBZ=-1.68488;SCBZ=0;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 17 376 . G <*> . . END=383;MIN_DP=7;QS=3,0 PL:DP 0,36,255:12 0,21,172:7 0,30,255:10 17 384 . A C,<*> 0 . DP=31;I16=19,11,0,1,1077,39885,4,16,1738,102482,60,3600,504,10988,25,625;QS=2.98419,0.0158103,0;SGB=-0.556633;RPBZ=0.615229;MQBZ=0.262613;MQSBZ=-0.333409;BQBZ=-1.68746;SCBZ=0;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,15,171,21,174,171:8:1 0,30,255,30,255,255:10:0 17 385 . C <*> . . END=400;MIN_DP=5;QS=3,0 PL:DP 0,36,255:12 0,15,133:5 0,30,255:10 17 401 . A C,<*> 0 . DP=29;I16=17,11,0,1,1063,41001,8,64,1587,92523,60,3600,501,11113,25,625;QS=2.97985,0.0201511,0;SGB=-0.556633;RPBZ=-0.478622;MQBZ=0.339683;MQSBZ=0.29364;BQBZ=-1.68267;SCBZ=0;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,15,160,15,160,160:5:0 0,22,255,30,255,255:11:1 17 402 . T <*> . . END=404;MIN_DP=5;QS=3,0 PL:DP 0,39,255:13 0,15,131:5 0,33,255:11 17 405 . T <*> . . END=411;MIN_DP=4;QS=3,0 PL:DP 0,39,255:13 0,12,109:4 0,30,244:10 17 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPBZ=-0.40473;MQBZ=0.267261;MQSBZ=-0.293785;BQBZ=-1.6942;SCBZ=0;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 17 413 . A <*> . . END=436;MIN_DP=3;QS=3,0 PL:DP 0,45,255:15 0,9,98:3 0,27,223:9 17 437 . T G,<*> 0 . DP=28;I16=13,14,1,0,990,36832,6,36,1558,91682,29,841,549,12435,16,256;QS=2.9781,0.0218978,0;SGB=-0.556633;RPBZ=-1.36214;MQBZ=-2.88675;MQSBZ=0.6;BQBZ=-1.67909;SCBZ=0;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,109,9,109,109:3:0 0,17,200,24,203,201:9:1 17 438 . A <*> . . END=464;MIN_DP=2;QS=3,0 PL:DP 0,48,255:16 0,6,97:2 0,27,198:9 17 465 . C T,<*> 0 . DP=33;I16=19,12,0,1,1173,45601,4,16,1775,103851,60,3600,589,12909,6,36;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.67982;MQBZ=0.321288;MQSBZ=0.341466;BQBZ=-1.68493;SCBZ=0;MQ0F=0 PL:DP:DV 0,51,255,51,255,255:17:0 0,15,158,15,158,158:5:0 0,20,224,27,227,224:10:1 17 466 . A <*> . . END=470;MIN_DP=5;QS=3,0 PL:DP 0,54,255:18 0,15,165:5 0,30,238:10 17 471 . T G,C,<*> 0 . DP=36;I16=21,12,0,2,1220,46380,18,162,1918,113282,97,4969,611,13281,16,256;QS=2.94529,0.0273556,0.0273556,0;VDB=0.96;SGB=0.346553;RPBZ=0.497712;MQBZ=-1.9761;MQSBZ=0.312094;BQBZ=-2.35032;SCBZ=0;MQ0F=0 PL:DP:DV 0,57,255,57,255,255,57,255,255,255:19:0 0,15,169,15,169,169,15,169,169,169:5:0 0,19,219,19,221,219,27,222,222,221:11:2 17 472 . T <*> . . END=487;MIN_DP=5;QS=3,0 PL:DP 0,51,255:17 0,15,146:5 0,30,241:10 17 488 . A G,<*> 0 . DP=35;I16=22,12,1,0,1278,48412,4,16,1986,117410,29,841,646,14380,25,625;QS=2.98947,0.0105263,0;SGB=-0.556633;RPBZ=0.594463;MQBZ=-3.36505;MQSBZ=0.10737;BQBZ=-1.69552;SCBZ=0;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,18,177,18,177,177:6:0 0,23,255,30,255,255:11:1 17 489 . A <*> . . END=511;MIN_DP=6;QS=3,0 PL:DP 0,51,255:17 0,18,175:6 0,24,221:8 17 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1133,41513,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97766,0.0223368,0;SGB=-0.556633;RPBZ=-1.47079;MQBZ=0.253876;MQSBZ=-0.461593;BQBZ=-1.68442;SCBZ=0;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 17 513 . A T,<*> 0 . DP=32;I16=21,10,1,0,1125,42283,12,144,1806,106610,60,3600,623,14249,15,225;QS=2.97966,0.020339,0;SGB=-0.556633;RPBZ=-1.24609;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.57376;SCBZ=0;MQ0F=0 PL:DP:DV 0,37,255,48,255,255:17:1 0,21,177,21,177,177:7:0 0,24,233,24,233,233:8:0 17 514 . A T,<*> 0 . DP=32;I16=22,9,0,1,1086,40204,16,256,1806,106610,60,3600,627,14381,11,121;QS=2.97127,0.0287253,0;SGB=-0.556633;RPBZ=-1.4628;MQBZ=0.258065;MQSBZ=-0.532795;BQBZ=-1.46657;SCBZ=0;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,21,172,21,172,172:7:0 0,24,235,24,235,235:8:0 17 515 . C <*> . . END=522;MIN_DP=5;QS=3,0 PL:DP 0,51,255:17 0,21,169:7 0,15,170:5 17 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPBZ=1.13742;MQBZ=0.179605;MQSBZ=-1.73205;BQBZ=-1.68805;SCBZ=0;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 17 524 . T <*> . . END=534;MIN_DP=5;QS=3,0 PL:DP 0,54,255:18 0,21,172:7 0,15,133:5 17 535 . A G,<*> 0 . DP=31;I16=24,6,0,1,1080,39870,8,64,1777,105769,60,3600,611,13341,25,625;QS=2.98623,0.0137694,0;SGB=-0.556633;RPBZ=-0.894788;MQBZ=0.182574;MQSBZ=-1.85164;BQBZ=-1.6854;SCBZ=0;MQ0F=0 PL:DP:DV 0,41,255,51,255,255:18:1 0,21,194,21,194,194:7:0 0,18,189,18,189,189:6:0 17 536 . C <*> . . END=547;MIN_DP=6;QS=3,0 PL:DP 0,54,255:18 0,21,166:7 0,18,157:6 17 548 . A C,<*> 0 . DP=33;I16=23,9,1,0,1153,42673,9,81,1866,110210,60,3600,561,12489,3,9;QS=2.98607,0.0139319,0;SGB=-0.556633;RPBZ=1.57584;MQBZ=0.253876;MQSBZ=-2.34521;BQBZ=-1.68939;SCBZ=3.80814;MQ0F=0 PL:DP:DV 0,44,255,54,255,255:19:1 0,21,181,21,181,181:7:0 0,21,211,21,211,211:7:0 17 549 . T G,<*> 0 . DP=32;I16=23,8,0,1,1135,42143,20,400,1806,106610,60,3600,532,11720,25,625;QS=2.96918,0.0308166,0;SGB=-0.556633;RPBZ=-0.487556;MQBZ=0.258065;MQSBZ=-2.29695;BQBZ=-1.68602;SCBZ=-0.258065;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 17 550 . T <*> . . END=558;MIN_DP=6;QS=3,0 PL:DP 0,45,255:15 0,18,143:6 0,18,177:6 17 559 . C A,<*> 0 . DP=27;I16=18,8,0,1,915,33775,14,196,1560,93600,29,841,473,10141,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPBZ=-1.02726;MQBZ=-5.09902;MQSBZ=-1.41421;BQBZ=-1.54776;SCBZ=5.09902;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 17 560 . C <*> . . END=565;MIN_DP=5;QS=3,0 PL:DP 0,45,255:15 0,15,121:5 0,21,154:7 17 566 . C A,<*> 0 . DP=29;I16=16,12,1,0,920,33998,9,81,1649,98041,60,3600,454,9734,25,625;QS=2.98321,0.016791,0;SGB=-0.556633;RPBZ=0.239193;MQBZ=0.188982;MQSBZ=-1.19024;BQBZ=-1.43942;SCBZ=-0.188982;MQ0F=0 PL:DP:DV 0,38,255,48,255,255:17:1 0,15,155,15,155,155:5:0 0,21,170,21,170,170:7:0 17 567 . C <*> . . END=573;MIN_DP=6;QS=3,0 PL:DP 0,48,255:16 0,18,156:6 0,18,175:6 17 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPBZ=-0.173514;MQBZ=-5.38516;MQSBZ=-1.22474;BQBZ=-1.68578;SCBZ=3.60588;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 17 575 . T C,<*> 0 . DP=30;I16=17,11,0,1,1048,41548,9,81,1680,100800,29,841,480,10426,25,625;QS=2.96786,0.0321429,0;SGB=-0.556633;RPBZ=-0.119685;MQBZ=-5.2915;MQSBZ=-1.19024;BQBZ=-1.68121;SCBZ=3.53589;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,13,200,21,203,202:8:1 0,15,163,15,163,163:5:0 17 576 . G <*> . . END=579;MIN_DP=5;QS=3,0 PL:DP 0,48,255:16 0,24,198:8 0,15,144:5 17 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPBZ=1.32953;MQBZ=0.185695;MQSBZ=-1.06904;BQBZ=-1.69093;SCBZ=-0.267102;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 17 581 . A <*> . . MIN_DP=5;QS=3,0 PL:DP 0,54,255:18 0,24,223:8 0,15,153:5 17 582 . C G,<*> 0 . DP=31;I16=15,15,1,0,1080,39870,8,64,1769,105241,60,3600,519,11211,15,225;QS=2.98734,0.0126582,0;SGB=-0.556633;RPBZ=1.34259;MQBZ=0.182574;MQSBZ=-1.0328;BQBZ=-1.68266;SCBZ=-0.262467;MQ0F=0 PL:DP:DV 0,41,255,51,255,255:18:1 0,24,207,24,207,207:8:0 0,15,151,15,151,151:5:0 17 583 . T <*> . . END=592;MIN_DP=5;QS=3,0 PL:DP 0,51,255:17 0,21,209:7 0,15,155:5 17 593 . C A,<*> 0 . DP=31;I16=16,14,0,1,1071,39925,7,49,1769,105241,29,841,561,12253,25,625;QS=2.97021,0.0297872,0;SGB=-0.556633;RPBZ=0.559355;MQBZ=-3.80789;MQSBZ=-0.0464238;BQBZ=-1.57464;SCBZ=3.67454;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,12,184,18,187,185:7:1 0,18,174,18,174,174:6:0 17 594 . A G,<*> 0 . DP=33;I16=16,16,1,0,1161,42757,4,16,1858,109682,60,3600,572,12672,15,225;QS=2.99359,0.00641026,0;SGB=-0.556633;RPBZ=-0.998367;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68954;SCBZ=-0.253876;MQ0F=0 PL:DP:DV 0,42,255,51,255,255:18:1 0,21,205,21,205,205:7:0 0,24,213,24,213,213:8:0 17 595 . A <*> . . MIN_DP=7;QS=3,0 PL:DP 0,54,255:18 0,21,198:7 0,24,218:8 17 596 . A G,<*> 0 . DP=33;I16=16,16,1,0,1061,37187,8,64,1858,109682,60,3600,590,12952,1,1;QS=2.98564,0.0143627,0;SGB=-0.556633;RPBZ=1.68146;MQBZ=0.254;MQSBZ=-0.0435607;BQBZ=-1.68357;SCBZ=-0.253876;MQ0F=0 PL:DP:DV 0,41,255,51,255,255:18:1 0,21,169,21,169,169:7:0 0,24,231,24,231,231:8:0 17 597 . C <*> . . END=600;MIN_DP=7;QS=3,0 PL:DP 0,51,255:17 0,21,194:7 0,24,220:8 bcftools-1.21/test/mpileup/mpileup.7.out000066400000000000000000000167601467060157400202770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00101 HG00102 17 100 . C <*> 0 . DP=9;I16=7,1,0,0,322,13492,0,0,449,26041,0,0,173,4019,0,0;QS=2,0;MQ0F=0 PL 0,9,118 0,15,134 17 101 . C <*> 0 . DP=9;I16=7,1,0,0,299,12029,0,0,449,26041,0,0,172,3954,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,132 17 102 . C <*> 0 . DP=9;I16=7,1,0,0,327,13835,0,0,449,26041,0,0,171,3895,0,0;QS=2,0;MQ0F=0 PL 0,9,121 0,15,139 17 103 . T <*> 0 . DP=9;I16=7,1,0,0,330,14238,0,0,449,26041,0,0,170,3842,0,0;QS=2,0;MQ0F=0 PL 0,9,118 0,15,147 17 104 . G <*> 0 . DP=9;I16=7,1,0,0,291,11939,0,0,449,26041,0,0,168,3746,0,0;QS=2,0;MQ0F=0 PL 0,9,101 0,15,133 17 105 . G <*> 0 . DP=9;I16=7,1,0,0,285,11215,0,0,449,26041,0,0,166,3658,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,125 17 106 . G <*> 0 . DP=9;I16=7,1,0,0,264,10620,0,0,449,26041,0,0,164,3578,0,0;QS=2,0;MQ0F=0 PL 0,9,92 0,15,124 17 107 . C <*> 0 . DP=9;I16=7,1,0,0,314,13030,0,0,449,26041,0,0,162,3506,0,0;QS=2,0;MQ0F=0 PL 0,9,119 0,15,136 17 108 . C <*> 0 . DP=9;I16=7,1,0,0,314,12964,0,0,449,26041,0,0,160,3442,0,0;QS=2,0;MQ0F=0 PL 0,9,119 0,15,135 17 109 . T <*> 0 . DP=9;I16=7,1,0,0,349,15565,0,0,449,26041,0,0,158,3386,0,0;QS=2,0;MQ0F=0 PL 0,9,120 0,15,150 17 110 . G <*> 0 . DP=9;I16=7,1,0,0,312,12794,0,0,449,26041,0,0,156,3338,0,0;QS=2,0;MQ0F=0 PL 0,9,113 0,15,136 17 111 . G <*> 0 . DP=9;I16=7,1,0,0,257,10693,0,0,449,26041,0,0,153,3249,0,0;QS=2,0;MQ0F=0 PL 0,9,95 0,15,119 17 112 . C <*> 0 . DP=9;I16=7,1,0,0,295,11875,0,0,449,26041,0,0,150,3170,0,0;QS=2,0;MQ0F=0 PL 0,9,103 0,15,135 17 113 . A <*> 0 . DP=9;I16=7,1,0,0,301,12565,0,0,449,26041,0,0,147,3101,0,0;QS=2,0;MQ0F=0 PL 0,9,102 0,15,139 17 114 . C <*> 0 . DP=9;I16=7,1,0,0,306,12386,0,0,449,26041,0,0,144,3042,0,0;QS=2,0;MQ0F=0 PL 0,9,113 0,15,133 17 115 . C A,<*> 0 . DP=11;I16=7,2,1,0,321,13261,12,144,509,29641,29,841,117,2369,25,625;QS=1.88785,0.11215,0;SGB=-0.516033;RPBZ=0.174608;MQBZ=-2;MQSBZ=-1.125;BQBZ=-1.23359;SCBZ=-0.496904;MQ0F=0 PL 3,0,86,9,89,93 0,21,153,21,153,153 17 116 . A <*> 0 . DP=11;I16=8,2,0,0,354,14068,0,0,538,30482,0,0,141,2959,0,0;QS=2,0;MQ0F=0 PL 0,9,102 0,21,175 17 117 . G <*> 0 . DP=11;I16=8,2,0,0,356,14150,0,0,538,30482,0,0,140,2938,0,0;QS=2,0;MQ0F=0 PL 0,9,97 0,21,177 17 118 . G <*> 0 . DP=11;I16=8,2,0,0,303,11685,0,0,538,30482,0,0,139,2931,0,0;QS=2,0;MQ0F=0 PL 0,9,65 0,21,162 17 119 . G <*> 0 . DP=10;I16=7,2,0,0,299,11343,0,0,478,26882,0,0,137,2887,0,0;QS=2,0;MQ0F=0 PL 0,6,76 0,21,160 17 120 . A <*> 0 . DP=10;I16=7,2,0,0,335,13257,0,0,478,26882,0,0,136,2854,0,0;QS=2,0;MQ0F=0 PL 0,6,88 0,21,171 17 121 . G <*> 0 . DP=10;I16=7,2,0,0,323,12457,0,0,478,26882,0,0,135,2831,0,0;QS=2,0;MQ0F=0 PL 0,6,84 0,21,168 17 122 . C <*> 0 . DP=11;I16=8,2,0,0,372,14904,0,0,538,30482,0,0,134,2818,0,0;QS=2,0;MQ0F=0 PL 0,9,107 0,21,178 17 123 . T <*> 0 . DP=10;I16=7,2,0,0,359,15071,0,0,478,26882,0,0,135,2815,0,0;QS=2,0;MQ0F=0 PL 0,9,123 0,18,166 17 124 . T <*> 0 . DP=10;I16=7,2,0,0,330,12968,0,0,478,26882,0,0,136,2822,0,0;QS=2,0;MQ0F=0 PL 0,9,114 0,18,154 17 125 . A <*> 0 . DP=10;I16=7,2,0,0,336,13370,0,0,478,26882,0,0,136,2790,0,0;QS=2,0;MQ0F=0 PL 0,9,114 0,18,162 17 126 . A <*> 0 . DP=10;I16=7,2,0,0,354,14758,0,0,478,26882,0,0,136,2770,0,0;QS=2,0;MQ0F=0 PL 0,9,117 0,18,174 17 127 . C <*> 0 . DP=10;I16=7,2,0,0,347,13991,0,0,478,26882,0,0,136,2762,0,0;QS=2,0;MQ0F=0 PL 0,9,119 0,18,160 17 128 . A <*> 0 . DP=10;I16=7,2,0,0,365,15241,0,0,478,26882,0,0,136,2766,0,0;QS=2,0;MQ0F=0 PL 0,9,121 0,18,168 17 129 . A <*> 0 . DP=9;I16=6,2,0,0,336,14562,0,0,418,23282,0,0,137,2781,0,0;QS=2,0;MQ0F=0 PL 0,9,124 0,15,159 17 130 . A <*> 0 . DP=9;I16=6,2,0,0,335,14487,0,0,418,23282,0,0,138,2806,0,0;QS=2,0;MQ0F=0 PL 0,9,124 0,15,152 17 131 . C <*> 0 . DP=9;I16=6,2,0,0,317,13093,0,0,418,23282,0,0,139,2841,0,0;QS=2,0;MQ0F=0 PL 0,9,120 0,15,147 17 132 . A <*> 0 . DP=9;I16=6,2,0,0,331,14103,0,0,418,23282,0,0,140,2886,0,0;QS=2,0;MQ0F=0 PL 0,9,120 0,15,151 17 133 . T <*> 0 . DP=8;I16=6,2,0,0,315,12451,0,0,418,23282,0,0,141,2941,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,150 17 134 . C <*> 0 . DP=8;I16=6,2,0,0,314,12374,0,0,418,23282,0,0,142,3006,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,152 17 135 . T <*> 0 . DP=8;I16=6,2,0,0,319,12845,0,0,418,23282,0,0,143,3081,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,159 17 136 . G <*> 0 . DP=8;I16=6,2,0,0,291,10787,0,0,418,23282,0,0,145,3165,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,134 17 137 . T <*> 0 . DP=8;I16=6,2,0,0,300,11444,0,0,418,23282,0,0,148,3258,0,0;QS=2,0;MQ0F=0 PL 0,9,104 0,15,139 17 138 . C <*> 0 . DP=8;I16=6,2,0,0,300,11542,0,0,418,23282,0,0,150,3312,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,142 17 139 . C <*> 0 . DP=8;I16=6,2,0,0,291,10833,0,0,418,23282,0,0,152,3378,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,143 17 140 . A <*> 0 . DP=8;I16=6,2,0,0,314,12410,0,0,418,23282,0,0,153,3405,0,0;QS=2,0;MQ0F=0 PL 0,9,107 0,15,153 17 141 . G <*> 0 . DP=8;I16=6,2,0,0,295,11151,0,0,418,23282,0,0,153,3391,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,142 17 142 . C <*> 0 . DP=8;I16=6,2,0,0,264,9036,0,0,418,23282,0,0,153,3385,0,0;QS=2,0;MQ0F=0 PL 0,9,97 0,15,129 17 143 . G <*> 0 . DP=8;I16=6,2,0,0,229,7291,0,0,418,23282,0,0,153,3387,0,0;QS=2,0;MQ0F=0 PL 0,9,95 0,15,102 17 144 . A <*> 0 . DP=8;I16=6,2,0,0,287,10705,0,0,418,23282,0,0,153,3397,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,129 17 145 . A <*> 0 . DP=8;I16=6,2,0,0,294,11200,0,0,418,23282,0,0,153,3415,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,138 17 146 . T <*> 0 . DP=8;I16=6,2,0,0,281,10419,0,0,418,23282,0,0,153,3441,0,0;QS=2,0;MQ0F=0 PL 0,9,103 0,15,128 17 147 . A <*> 0 . DP=8;I16=6,2,0,0,286,10442,0,0,418,23282,0,0,153,3475,0,0;QS=2,0;MQ0F=0 PL 0,9,99 0,15,140 17 148 . C <*> 0 . DP=8;I16=6,2,0,0,301,11401,0,0,418,23282,0,0,152,3466,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,146 17 149 . C <*> 0 . DP=8;I16=6,2,0,0,293,10907,0,0,418,23282,0,0,150,3414,0,0;QS=2,0;MQ0F=0 PL 0,9,109 0,15,140 17 150 . T <*> 0 . DP=7;I16=5,2,0,0,277,11093,0,0,389,22441,0,0,149,3369,0,0;QS=2,0;MQ0F=0 PL 0,6,84 0,15,152 bcftools-1.21/test/mpileup/mpileup.8.out000066400000000000000000000173671467060157400203040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 17 100 . C <*> 0 . DP=9;I16=9,0,0,0,350,14094,0,0,509,29641,0,0,159,3427,0,0;QS=1,0;MQ0F=0 PL 0,27,189 17 101 . C <*> 0 . DP=9;I16=9,0,0,0,331,12701,0,0,509,29641,0,0,159,3349,0,0;QS=1,0;MQ0F=0 PL 0,27,182 17 102 . C <*> 0 . DP=9;I16=9,0,0,0,349,13977,0,0,509,29641,0,0,159,3283,0,0;QS=1,0;MQ0F=0 PL 0,27,188 17 103 . T C,<*> 0 . DP=9;I16=8,0,1,0,338,14304,6,36,480,28800,29,841,153,3193,6,36;QS=0.982558,0.0174419,0;SGB=-0.379885;RPBZ=-0.774597;MQBZ=-2.82843;BQBZ=-1.62549;SCBZ=2.82843;MQ0F=0 PL 0,17,184,24,187,185 17 104 . G C,<*> 0 . DP=9;I16=8,0,1,0,310,12224,3,9,480,28800,29,841,152,3138,7,49;QS=0.987261,0.0127389,0;SGB=-0.379885;RPBZ=-0.774597;MQBZ=-2.82843;BQBZ=-1.56227;SCBZ=2.82843;MQ0F=0 PL 0,18,173,24,176,173 17 105 . G <*> 0 . DP=10;I16=10,0,0,0,318,11136,0,0,569,33241,0,0,159,3157,0,0;QS=1,0;MQ0F=0 PL 0,30,171 17 106 . G <*> 0 . DP=10;I16=10,0,0,0,372,14438,0,0,569,33241,0,0,160,3140,0,0;QS=1,0;MQ0F=0 PL 0,30,190 17 107 . C <*> 0 . DP=10;I16=10,0,0,0,372,14922,0,0,569,33241,0,0,161,3137,0,0;QS=1,0;MQ0F=0 PL 0,30,192 17 108 . C <*> 0 . DP=10;I16=10,0,0,0,367,14465,0,0,569,33241,0,0,162,3148,0,0;QS=1,0;MQ0F=0 PL 0,30,190 17 109 . T C,<*> 0 . DP=10;I16=9,0,1,0,367,15083,2,4,540,32400,29,841,151,3029,12,144;QS=0.989218,0.0107817,0;SGB=-0.379885;RPBZ=-0.522233;MQBZ=-3;BQBZ=-1.59099;SCBZ=3;MQ0F=0 PL 0,20,191,27,194,191 17 110 . G <*> 0 . DP=10;I16=10,0,0,0,376,15242,0,0,569,33241,0,0,164,3212,0,0;QS=1,0;MQ0F=0 PL 0,30,194 17 111 . G <*> 0 . DP=10;I16=10,0,0,0,316,10760,0,0,569,33241,0,0,165,3265,0,0;QS=1,0;MQ0F=0 PL 0,30,167 17 112 . C G,<*> 0 . DP=10;I16=9,0,1,0,362,14690,2,4,540,32400,29,841,151,3107,15,225;QS=0.989071,0.010929,0;SGB=-0.379885;RPBZ=-0.174078;MQBZ=-3;BQBZ=-1.61126;SCBZ=3;MQ0F=0 PL 0,20,187,27,190,187 17 113 . A G,<*> 0 . DP=10;I16=9,0,1,0,334,12490,4,16,540,32400,29,841,150,3106,16,256;QS=0.988166,0.0118343,0;SGB=-0.379885;RPBZ=-0.174078;MQBZ=-3;BQBZ=-1.57628;SCBZ=3;MQ0F=0 PL 0,20,172,27,175,172 17 114 . C <*> 0 . DP=10;I16=10,0,0,0,354,13490,0,0,569,33241,0,0,166,3404,0,0;QS=1,0;MQ0F=0 PL 0,30,181 17 115 . C <*> 0 . DP=10;I16=10,0,0,0,367,14165,0,0,569,33241,0,0,166,3458,0,0;QS=1,0;MQ0F=0 PL 0,30,189 17 116 . A C,<*> 0 . DP=10;I16=9,0,1,0,351,13723,2,4,540,32400,29,841,146,3114,19,361;QS=0.988732,0.0112676,0;SGB=-0.379885;RPBZ=0.174078;MQBZ=-3;BQBZ=-1.59099;SCBZ=3;MQ0F=0 PL 0,20,179,27,182,179 17 117 . G <*> 0 . DP=10;I16=10,0,0,0,359,13895,0,0,569,33241,0,0,164,3506,0,0;QS=1,0;MQ0F=0 PL 0,30,185 17 118 . G <*> 0 . DP=9;I16=9,0,0,0,317,11785,0,0,509,29641,0,0,164,3550,0,0;QS=1,0;MQ0F=0 PL 0,27,175 17 119 . G <*> 0 . DP=9;I16=9,0,0,0,320,12116,0,0,509,29641,0,0,164,3606,0,0;QS=1,0;MQ0F=0 PL 0,27,176 17 120 . A G,<*> 0 . DP=9;I16=8,0,1,0,311,12135,4,16,480,28800,29,841,141,3145,23,529;QS=0.987302,0.0126984,0;SGB=-0.379885;RPBZ=0.387298;MQBZ=-2.82843;BQBZ=-1.55569;SCBZ=2.82843;MQ0F=0 PL 0,18,171,24,174,171 17 121 . G <*> 0 . DP=9;I16=9,0,0,0,327,12691,0,0,509,29641,0,0,163,3703,0,0;QS=1,0;MQ0F=0 PL 0,27,181 17 122 . C <*> 0 . DP=9;I16=9,0,0,0,324,12880,0,0,509,29641,0,0,162,3742,0,0;QS=1,0;MQ0F=0 PL 0,27,180 17 123 . T <*> 0 . DP=8;I16=8,0,0,0,288,11074,0,0,449,26041,0,0,161,3739,0,0;QS=1,0;MQ0F=0 PL 0,24,170 17 124 . T <*> 0 . DP=9;I16=9,0,0,0,276,9034,0,0,509,29641,0,0,160,3742,0,0;QS=1,0;MQ0F=0 PL 0,27,154 17 125 . A T,<*> 0 . DP=8;I16=7,0,1,0,253,9195,4,16,420,25200,29,841,136,3126,25,625;QS=0.984436,0.0155642,0;SGB=-0.379885;RPBZ=1.09109;MQBZ=-2.64575;BQBZ=-1.5367;SCBZ=2.64575;MQ0F=0 PL 0,15,149,21,152,149 17 126 . A <*> 0 . DP=8;I16=8,0,0,0,275,9967,0,0,449,26041,0,0,162,3766,0,0;QS=1,0;MQ0F=0 PL 0,24,162 17 127 . C <*> 0 . DP=8;I16=8,0,0,0,280,10340,0,0,449,26041,0,0,163,3787,0,0;QS=1,0;MQ0F=0 PL 0,24,163 17 128 . A <*> 0 . DP=8;I16=8,0,0,0,295,11123,0,0,449,26041,0,0,164,3814,0,0;QS=1,0;MQ0F=0 PL 0,24,169 17 129 . A <*> 0 . DP=8;I16=8,0,0,0,291,10845,0,0,449,26041,0,0,165,3847,0,0;QS=1,0;MQ0F=0 PL 0,24,168 17 130 . A <*> 0 . DP=8;I16=8,0,0,0,292,10932,0,0,449,26041,0,0,166,3886,0,0;QS=1,0;MQ0F=0 PL 0,24,169 17 131 . C <*> 0 . DP=7;I16=7,0,0,0,276,10910,0,0,420,25200,0,0,141,3255,0,0;QS=1,0;MQ0F=0 PL 0,21,167 17 132 . A <*> 0 . DP=7;I16=7,0,0,0,279,11147,0,0,420,25200,0,0,141,3253,0,0;QS=1,0;MQ0F=0 PL 0,21,169 17 133 . T <*> 0 . DP=7;I16=7,0,0,0,269,10365,0,0,420,25200,0,0,141,3255,0,0;QS=1,0;MQ0F=0 PL 0,21,163 17 134 . C <*> 0 . DP=7;I16=7,0,0,0,293,12279,0,0,420,25200,0,0,141,3261,0,0;QS=1,0;MQ0F=0 PL 0,21,177 17 135 . T <*> 0 . DP=7;I16=7,0,0,0,286,11708,0,0,420,25200,0,0,141,3271,0,0;QS=1,0;MQ0F=0 PL 0,21,173 17 136 . G <*> 0 . DP=7;I16=7,0,0,0,283,11471,0,0,420,25200,0,0,141,3285,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 137 . T <*> 0 . DP=7;I16=7,0,0,0,263,9933,0,0,420,25200,0,0,141,3303,0,0;QS=1,0;MQ0F=0 PL 0,21,160 17 138 . C <*> 0 . DP=7;I16=7,0,0,0,284,11546,0,0,420,25200,0,0,141,3325,0,0;QS=1,0;MQ0F=0 PL 0,21,172 17 139 . C <*> 0 . DP=7;I16=7,0,0,0,263,9957,0,0,420,25200,0,0,140,3302,0,0;QS=1,0;MQ0F=0 PL 0,21,161 17 140 . A <*> 0 . DP=7;I16=7,0,0,0,269,10379,0,0,420,25200,0,0,139,3285,0,0;QS=1,0;MQ0F=0 PL 0,21,163 17 141 . G <*> 0 . DP=6;I16=6,0,0,0,239,9599,0,0,360,21600,0,0,139,3273,0,0;QS=1,0;MQ0F=0 PL 0,18,158 17 142 . C <*> 0 . DP=6;I16=6,0,0,0,239,9557,0,0,360,21600,0,0,139,3265,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 143 . G <*> 0 . DP=6;I16=6,0,0,0,197,6487,0,0,360,21600,0,0,139,3261,0,0;QS=1,0;MQ0F=0 PL 0,18,128 17 144 . A <*> 0 . DP=6;I16=6,0,0,0,232,9020,0,0,360,21600,0,0,138,3212,0,0;QS=1,0;MQ0F=0 PL 0,18,152 17 145 . A <*> 0 . DP=6;I16=6,0,0,0,233,9089,0,0,360,21600,0,0,137,3169,0,0;QS=1,0;MQ0F=0 PL 0,18,153 17 146 . T <*> 0 . DP=6;I16=6,0,0,0,233,9065,0,0,360,21600,0,0,136,3132,0,0;QS=1,0;MQ0F=0 PL 0,18,152 17 147 . A <*> 0 . DP=6;I16=6,0,0,0,229,8771,0,0,360,21600,0,0,135,3101,0,0;QS=1,0;MQ0F=0 PL 0,18,150 17 148 . C <*> 0 . DP=6;I16=6,0,0,0,240,9618,0,0,360,21600,0,0,134,3076,0,0;QS=1,0;MQ0F=0 PL 0,18,157 17 149 . C <*> 0 . DP=6;I16=6,0,0,0,219,8419,0,0,360,21600,0,0,133,3057,0,0;QS=1,0;MQ0F=0 PL 0,18,148 17 150 . T <*> 0 . DP=6;I16=6,0,0,0,234,9158,0,0,360,21600,0,0,131,2993,0,0;QS=1,0;MQ0F=0 PL 0,18,153 bcftools-1.21/test/mpileup/mpileup.9.out000066400000000000000000000167601467060157400203010ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##ALT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1 SAMPLE2 17 100 . C <*> 0 . DP=9;I16=7,1,0,0,322,13492,0,0,449,26041,0,0,173,4019,0,0;QS=2,0;MQ0F=0 PL 0,9,118 0,15,134 17 101 . C <*> 0 . DP=9;I16=7,1,0,0,299,12029,0,0,449,26041,0,0,172,3954,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,132 17 102 . C <*> 0 . DP=9;I16=7,1,0,0,327,13835,0,0,449,26041,0,0,171,3895,0,0;QS=2,0;MQ0F=0 PL 0,9,121 0,15,139 17 103 . T <*> 0 . DP=9;I16=7,1,0,0,330,14238,0,0,449,26041,0,0,170,3842,0,0;QS=2,0;MQ0F=0 PL 0,9,118 0,15,147 17 104 . G <*> 0 . DP=9;I16=7,1,0,0,291,11939,0,0,449,26041,0,0,168,3746,0,0;QS=2,0;MQ0F=0 PL 0,9,101 0,15,133 17 105 . G <*> 0 . DP=9;I16=7,1,0,0,285,11215,0,0,449,26041,0,0,166,3658,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,125 17 106 . G <*> 0 . DP=9;I16=7,1,0,0,264,10620,0,0,449,26041,0,0,164,3578,0,0;QS=2,0;MQ0F=0 PL 0,9,92 0,15,124 17 107 . C <*> 0 . DP=9;I16=7,1,0,0,314,13030,0,0,449,26041,0,0,162,3506,0,0;QS=2,0;MQ0F=0 PL 0,9,119 0,15,136 17 108 . C <*> 0 . DP=9;I16=7,1,0,0,314,12964,0,0,449,26041,0,0,160,3442,0,0;QS=2,0;MQ0F=0 PL 0,9,119 0,15,135 17 109 . T <*> 0 . DP=9;I16=7,1,0,0,349,15565,0,0,449,26041,0,0,158,3386,0,0;QS=2,0;MQ0F=0 PL 0,9,120 0,15,150 17 110 . G <*> 0 . DP=9;I16=7,1,0,0,312,12794,0,0,449,26041,0,0,156,3338,0,0;QS=2,0;MQ0F=0 PL 0,9,113 0,15,136 17 111 . G <*> 0 . DP=9;I16=7,1,0,0,257,10693,0,0,449,26041,0,0,153,3249,0,0;QS=2,0;MQ0F=0 PL 0,9,95 0,15,119 17 112 . C <*> 0 . DP=9;I16=7,1,0,0,295,11875,0,0,449,26041,0,0,150,3170,0,0;QS=2,0;MQ0F=0 PL 0,9,103 0,15,135 17 113 . A <*> 0 . DP=9;I16=7,1,0,0,301,12565,0,0,449,26041,0,0,147,3101,0,0;QS=2,0;MQ0F=0 PL 0,9,102 0,15,139 17 114 . C <*> 0 . DP=9;I16=7,1,0,0,306,12386,0,0,449,26041,0,0,144,3042,0,0;QS=2,0;MQ0F=0 PL 0,9,113 0,15,133 17 115 . C A,<*> 0 . DP=11;I16=7,2,1,0,321,13261,12,144,509,29641,29,841,117,2369,25,625;QS=1.88785,0.11215,0;SGB=-0.516033;RPBZ=0.174608;MQBZ=-2;MQSBZ=-1.125;BQBZ=-1.23359;SCBZ=-0.496904;MQ0F=0 PL 3,0,86,9,89,93 0,21,153,21,153,153 17 116 . A <*> 0 . DP=11;I16=8,2,0,0,354,14068,0,0,538,30482,0,0,141,2959,0,0;QS=2,0;MQ0F=0 PL 0,9,102 0,21,175 17 117 . G <*> 0 . DP=11;I16=8,2,0,0,356,14150,0,0,538,30482,0,0,140,2938,0,0;QS=2,0;MQ0F=0 PL 0,9,97 0,21,177 17 118 . G <*> 0 . DP=11;I16=8,2,0,0,303,11685,0,0,538,30482,0,0,139,2931,0,0;QS=2,0;MQ0F=0 PL 0,9,65 0,21,162 17 119 . G <*> 0 . DP=10;I16=7,2,0,0,299,11343,0,0,478,26882,0,0,137,2887,0,0;QS=2,0;MQ0F=0 PL 0,6,76 0,21,160 17 120 . A <*> 0 . DP=10;I16=7,2,0,0,335,13257,0,0,478,26882,0,0,136,2854,0,0;QS=2,0;MQ0F=0 PL 0,6,88 0,21,171 17 121 . G <*> 0 . DP=10;I16=7,2,0,0,323,12457,0,0,478,26882,0,0,135,2831,0,0;QS=2,0;MQ0F=0 PL 0,6,84 0,21,168 17 122 . C <*> 0 . DP=11;I16=8,2,0,0,372,14904,0,0,538,30482,0,0,134,2818,0,0;QS=2,0;MQ0F=0 PL 0,9,107 0,21,178 17 123 . T <*> 0 . DP=10;I16=7,2,0,0,359,15071,0,0,478,26882,0,0,135,2815,0,0;QS=2,0;MQ0F=0 PL 0,9,123 0,18,166 17 124 . T <*> 0 . DP=10;I16=7,2,0,0,330,12968,0,0,478,26882,0,0,136,2822,0,0;QS=2,0;MQ0F=0 PL 0,9,114 0,18,154 17 125 . A <*> 0 . DP=10;I16=7,2,0,0,336,13370,0,0,478,26882,0,0,136,2790,0,0;QS=2,0;MQ0F=0 PL 0,9,114 0,18,162 17 126 . A <*> 0 . DP=10;I16=7,2,0,0,354,14758,0,0,478,26882,0,0,136,2770,0,0;QS=2,0;MQ0F=0 PL 0,9,117 0,18,174 17 127 . C <*> 0 . DP=10;I16=7,2,0,0,347,13991,0,0,478,26882,0,0,136,2762,0,0;QS=2,0;MQ0F=0 PL 0,9,119 0,18,160 17 128 . A <*> 0 . DP=10;I16=7,2,0,0,365,15241,0,0,478,26882,0,0,136,2766,0,0;QS=2,0;MQ0F=0 PL 0,9,121 0,18,168 17 129 . A <*> 0 . DP=9;I16=6,2,0,0,336,14562,0,0,418,23282,0,0,137,2781,0,0;QS=2,0;MQ0F=0 PL 0,9,124 0,15,159 17 130 . A <*> 0 . DP=9;I16=6,2,0,0,335,14487,0,0,418,23282,0,0,138,2806,0,0;QS=2,0;MQ0F=0 PL 0,9,124 0,15,152 17 131 . C <*> 0 . DP=9;I16=6,2,0,0,317,13093,0,0,418,23282,0,0,139,2841,0,0;QS=2,0;MQ0F=0 PL 0,9,120 0,15,147 17 132 . A <*> 0 . DP=9;I16=6,2,0,0,331,14103,0,0,418,23282,0,0,140,2886,0,0;QS=2,0;MQ0F=0 PL 0,9,120 0,15,151 17 133 . T <*> 0 . DP=8;I16=6,2,0,0,315,12451,0,0,418,23282,0,0,141,2941,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,150 17 134 . C <*> 0 . DP=8;I16=6,2,0,0,314,12374,0,0,418,23282,0,0,142,3006,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,152 17 135 . T <*> 0 . DP=8;I16=6,2,0,0,319,12845,0,0,418,23282,0,0,143,3081,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,159 17 136 . G <*> 0 . DP=8;I16=6,2,0,0,291,10787,0,0,418,23282,0,0,145,3165,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,134 17 137 . T <*> 0 . DP=8;I16=6,2,0,0,300,11444,0,0,418,23282,0,0,148,3258,0,0;QS=2,0;MQ0F=0 PL 0,9,104 0,15,139 17 138 . C <*> 0 . DP=8;I16=6,2,0,0,300,11542,0,0,418,23282,0,0,150,3312,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,142 17 139 . C <*> 0 . DP=8;I16=6,2,0,0,291,10833,0,0,418,23282,0,0,152,3378,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,143 17 140 . A <*> 0 . DP=8;I16=6,2,0,0,314,12410,0,0,418,23282,0,0,153,3405,0,0;QS=2,0;MQ0F=0 PL 0,9,107 0,15,153 17 141 . G <*> 0 . DP=8;I16=6,2,0,0,295,11151,0,0,418,23282,0,0,153,3391,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,142 17 142 . C <*> 0 . DP=8;I16=6,2,0,0,264,9036,0,0,418,23282,0,0,153,3385,0,0;QS=2,0;MQ0F=0 PL 0,9,97 0,15,129 17 143 . G <*> 0 . DP=8;I16=6,2,0,0,229,7291,0,0,418,23282,0,0,153,3387,0,0;QS=2,0;MQ0F=0 PL 0,9,95 0,15,102 17 144 . A <*> 0 . DP=8;I16=6,2,0,0,287,10705,0,0,418,23282,0,0,153,3397,0,0;QS=2,0;MQ0F=0 PL 0,9,105 0,15,129 17 145 . A <*> 0 . DP=8;I16=6,2,0,0,294,11200,0,0,418,23282,0,0,153,3415,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,138 17 146 . T <*> 0 . DP=8;I16=6,2,0,0,281,10419,0,0,418,23282,0,0,153,3441,0,0;QS=2,0;MQ0F=0 PL 0,9,103 0,15,128 17 147 . A <*> 0 . DP=8;I16=6,2,0,0,286,10442,0,0,418,23282,0,0,153,3475,0,0;QS=2,0;MQ0F=0 PL 0,9,99 0,15,140 17 148 . C <*> 0 . DP=8;I16=6,2,0,0,301,11401,0,0,418,23282,0,0,152,3466,0,0;QS=2,0;MQ0F=0 PL 0,9,106 0,15,146 17 149 . C <*> 0 . DP=8;I16=6,2,0,0,293,10907,0,0,418,23282,0,0,150,3414,0,0;QS=2,0;MQ0F=0 PL 0,9,109 0,15,140 17 150 . T <*> 0 . DP=7;I16=5,2,0,0,277,11093,0,0,389,22441,0,0,149,3369,0,0;QS=2,0;MQ0F=0 PL 0,6,84 0,15,152 bcftools-1.21/test/mpileup/mpileup.ref.fa000066400000000000000000000102741467060157400204560ustar00rootroot00000000000000>17 17:1-4200 AAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAA TGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGA GCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAA GACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAGACAC GCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACA GTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGA AAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATA AATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAG GAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATC ACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTG TGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACAT GCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGG CAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGA AAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGA TTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTAC CAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAG TGCTGAGGTGGGAAGATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCG CCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAA GAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGAC CAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGT TCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC CCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGAC GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCC CGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTA GGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGA GCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTT TGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGC CACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAG CGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCA CTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCC TGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGG TCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACA GTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGC CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCAC GGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGC AGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGC ACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCG GCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAG CTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATC GTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAA AAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGG AGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCG CATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCAAAAAAGAAAGGAAGAA ATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGG CCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCT CTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTAT TTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGG ACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATG TGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCT TTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAG CAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTG CCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAG ACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGG GCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTA ATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCA GCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTG GCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGG GAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGT AAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCC TGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATAT ATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTG TTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTAC ACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGC CTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCG TCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCAT GCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAT GGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCT ACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATAT TCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTT CTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCAC bcftools-1.21/test/mpileup/mpileup.ref.fa.fai000066400000000000000000000000211467060157400212010ustar00rootroot0000000000000017 4200 14 60 61 bcftools-1.21/test/mplp.10.samples000066400000000000000000000001341467060157400170140ustar00rootroot00000000000000ERR162872 ERR162875 SAMPLE1a ERR013140 SAMPLE1b ERR229776 SAMPLE2 ERR229775 SAMPLE3 bcftools-1.21/test/mplp.11.rgs000066400000000000000000000000121467060157400161370ustar00rootroot00000000000000ERR229775 bcftools-1.21/test/mplp.9.samples000066400000000000000000000000401467060157400167400ustar00rootroot00000000000000HG00101 SAMPLE1 HG00102 SAMPLE2 bcftools-1.21/test/mplp.samples000066400000000000000000000000201467060157400165670ustar00rootroot00000000000000HG00101 HG00102 bcftools-1.21/test/norm.2.fa000066400000000000000000000000561467060157400156650ustar00rootroot00000000000000>1 1:115254041-115254060 AAaccccaagtctactaaAA bcftools-1.21/test/norm.2.out000066400000000000000000000003541467060157400161070ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . G . . . . 1 10 . g gTC . . . 1 10 . g gtC . . . 1 13 . T . . . . 1 14 . a aGC . . . bcftools-1.21/test/norm.2.vcf000066400000000000000000000002701467060157400160530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . G . . . . 1 11 . T TCT . . . 1 12 . C CTC . . . 1 13 . T . . . . 1 14 . B BGC . . . bcftools-1.21/test/norm.3.2.out000066400000000000000000000003101467060157400162400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=norm.3.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 9 . TCA T . . . 1 11 . N C . . . bcftools-1.21/test/norm.3.fa000066400000000000000000000000311467060157400156570ustar00rootroot00000000000000>1 GGGGCGGTTCACGAACCTGCG bcftools-1.21/test/norm.3.out000066400000000000000000000003101467060157400161000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=norm.3.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 9 . TCA T . . . 1 11 . A C . . . bcftools-1.21/test/norm.3.vcf000066400000000000000000000002251467060157400160540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=norm.3.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . NAC N . . . 1 11 . N C . . . bcftools-1.21/test/norm.4.1.out000066400000000000000000000004461467060157400162520ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 10 . T C . . . GT 0/1 1 10 . T TAC,TATAC,TATATAC,TATATATAC . . . GT 0/2 bcftools-1.21/test/norm.4.2.out000066400000000000000000000004201467060157400162430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 10 . T C,TAC,TATAC,TATATAC,TATATATAC . . . GT 3/1 bcftools-1.21/test/norm.4.vcf000066400000000000000000000004641467060157400160620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 1 10 . T C . . . GT 0/1 1 10 . T TAC . . . GT 0/0 1 10 . T TATAC . . . GT 0/1 1 10 . T TATATAC . . . GT 0/0 1 10 . T TATATATAC . . . GT 0/0 bcftools-1.21/test/norm.5.1.out000066400000000000000000000005271467060157400162530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 511 . CAGCA CAG . . . GT 1|0 0|1 1 511 . CAGCA CAA . . . GT 0|0 1|0 1 511 . CAGCA CCA . . . GT 0|0 0|0 bcftools-1.21/test/norm.5.2.out000066400000000000000000000005271467060157400162540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 511 . CAGCA CAG . . . GT 1|0 .|1 1 511 . CAGCA CAA . . . GT .|0 1|. 1 511 . CAGCA CCA . . . GT .|0 .|. bcftools-1.21/test/norm.5.vcf000066400000000000000000000003451467060157400160610ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 511 . CAGCA CAG,CAA,CCA . . . GT 1|0 2|1 bcftools-1.21/test/norm.atom-split-norm.1.out000066400000000000000000000005761467060157400211550ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///ref.fa ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 3 . GGCGCGGA G . . ORI=chr1|5|CGCGGAGG|C,G|2 chr1 5 . CGCGGAGG C . . ORI=chr1|5|CGCGGAGG|C,G|1 bcftools-1.21/test/norm.atom-split-norm.fa000066400000000000000000000000261467060157400205630ustar00rootroot00000000000000>chr1 AAGGCGCGGAGGAAA bcftools-1.21/test/norm.atom-split-norm.vcf000066400000000000000000000002301467060157400207500ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///ref.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 5 . CGCGGAGG C,G . . . bcftools-1.21/test/norm.fa000066400000000000000000000022621467060157400155260ustar00rootroot00000000000000>20 20:1339000-1339300 AGGATGGGGCTCATTAATAGAGCTCCACTTGTCTCCAGAATCACTGGTGAGGAAGGGGAG TGTTGCCCCCACATTCGTGCACAGCAGGGATGGTTCACCGAACTCCACACCAGTCTCTGC AGAGCCTGTTGGGGAGAGGAGGGCTGTGGTTTCTTTGATGGTGTTCACCTGGAGTAGAGC AAGTATTGTCAAAAGGGTCATCCTCGGAGGTTGCAGTGAGCCGAGATCGCACCATTGCAC TGCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAGGCCAT C >1 1:10143-10443 CTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCTAACCCTAACCCTAACCCTAACC CTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAAACCCTAAACCCTA ACCCTAACCCTAACCCTAACCCTAACCCCAACCCCAACCCCAACCCCAACCCCAACCCCA ACCCTAACCCCTAACCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTA ACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCC >2 1:1382388-1382602 GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTA TTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTT GAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTG CAAGCTCCACCTCCTGGGTTCACGCCATTCTCCTG >3 madeup ACTGGACACGTGGACACACACACACACACACACACACACACAGTCAAACCACCTACCAGA >4 20:8917026-8917085 TCCCCTCTTGACCTCTCTCTATTTTTTTTTTTTTTTCTGAGATGGATTTTTGCTCTTGTT >5 20:18724313-18724343 GTCTCAAAAAAAAAAAAAAAAAAAAGAAAAG >21 TTTATTATTATTATTATTAAATTGAATTTATTTAGTGTACATACATTCATGTGTATTGTG >22 NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN bcftools-1.21/test/norm.iupac.fa000066400000000000000000000000671467060157400166270ustar00rootroot00000000000000>1 1:115254041-115254060 AAaccccNagtctactaaAA 12345678 bcftools-1.21/test/norm.iupac.out000066400000000000000000000002421467060157400170430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 8 . N NA . . . bcftools-1.21/test/norm.iupac.vcf000066400000000000000000000001601467060157400170110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 8 . BA BAA . . . bcftools-1.21/test/norm.join-missing-ploidy.1.out000066400000000000000000000005021467060157400220040ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##fileDate=20190708 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE_ONE SAMPLE_TWO chr1 100 . A T,C . . . GT 0/1 2 chr1 200 . A C,T . . . GT 0/2 1 bcftools-1.21/test/norm.join-missing-ploidy.vcf000066400000000000000000000005061467060157400216200ustar00rootroot00000000000000##fileformat=VCFv4.1 ##fileDate=20190708 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE_ONE SAMPLE_TWO chr1 100 . A T . . . GT 0/1 ./. chr1 100 . A C . . . GT . 1 chr1 200 . A C . . . GT . 1 chr1 200 . A T . . . GT 0/1 ./. bcftools-1.21/test/norm.m-any.1.out000066400000000000000000000007451467060157400171320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT Samp1 Samp2 chr1 98 . GCCT G . . . IR:FR:IA:FA 1,2:.,.:.:. .,.:1,2:1:1 chr1 98 . GCCT GC . . . IR:FR:IA:FA 1,3:.,.:.:. .,.:1,3:2:2 bcftools-1.21/test/norm.m-any.vcf000066400000000000000000000005661467060157400167430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT Samp1 Samp2 chr1 98 . GCCT G,GC . . . IR:FR:IA:FA 1,2,3 .:1,2,3:1,2:1,2 bcftools-1.21/test/norm.merge.2.out000066400000000000000000000050031467060157400172010ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 XY00003 1 105 . T C 999 PASS . GT:FGI:FRI 1:1,2:3,4 0/1:5,6,7:8,9 0/1:.:.,. 1 110 . C A 999 PASS . GT:FGI 1:1,2 0:3,4 0:. 1 150 . A C 999 PASS . GT:FGI 1:1,2 0:. 0:3,4 bcftools-1.21/test/norm.merge.2.vcf000066400000000000000000000052151467060157400171550ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 XY00003 1 105 . T . 999 PASS . GT:FGI:FRI 0:.:. 0/0:.:. 0/0:.:. 1 105 . T C 999 PASS . GT:FGI:FRI 1:1,2:3,4 0/1:5,6,7:8,9 0/1:.:. 1 110 . C . 999 PASS . GT:FGI 0:. 0:. 0:. 1 110 . C A 999 PASS . GT:FGI 1:1,2 0:3,4 0:. 1 150 . A . 999 PASS . GT:FGI 0:. 0:. 0:. 1 150 . A C 999 PASS . GT:FGI 1:1,2 0:. 0:3,4 bcftools-1.21/test/norm.merge.3.out000066400000000000000000000062741467060157400172150ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample_1 sample_2 11 48245184 . C G . PASS FL=0.34;FLG=0.1,0,0.9;FLA=88.4;FLR=99,88.4;INT=0;INTG=0,1,9;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta;STG=alpha,beta,gamma GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9:88.4:99,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:0.1,0,0.9:88.4:99,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 11 48245185 . C G,T . PASS FL=0.34;FLG=0.1,0,0.9,.,.,.;FLA=88.4,.;FLR=99,88.4,.;INT=0;INTG=0,1,9,.,.,.;INTA=88,.;INTR=99,88,.;F1;ST=alpha;STA=alpha,.;STR=alpha,beta,.;STG=alpha,beta,gamma,.,.,. GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9,.,.,.:88.4,.:99,88.4,.:0:0,1,9,.,.,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,gamma,.,.,. 0|0:0.34:0.1,0,0.9,.,.,.:88.4,.:99,88.4,.:0:0,1,9,.,.,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,gamma,.,.,. 11 48245186 . C G,T . PASS FL=0.34;FLA=88.4,88.4;FLR=99,88.4,88.4;INT=0;INTA=88,11;INTR=99,88,11;F1;ST=alpha;STA=alpha,beta;STR=alpha,beta,gamma GT:FL:FLA:FLR:INT:INTA:INTR:ST:STA:STR 0|0:0.34:88.4,11:99,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:88.4,11:99,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma 11 48245187 . C G,T . PASS FL=0.34;FLA=88.4,.;FLR=99,88.4,.;INT=0;INTA=88,.;INTR=99,88,.;F1;ST=alpha;STA=alpha,.;STR=alpha,beta,. GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0:0.34:0.1,0,.:88.4,.:99,88.4,.:0:0,1,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,. 0:0.34:0.1,0,.:88.4,.:99,88.4,.:0:0,1,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,. bcftools-1.21/test/norm.merge.3.vcf000066400000000000000000000062461467060157400171630ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample_1 sample_2 11 48245184 . C G . PASS FL=0.34;FLG=0.1,0,0.9;FLA=88.4;FLR=99.0,88.4;INT=0;INTG=0,1,9;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta;STG=alpha,beta,gamma GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 11 48245184 . C G . PASS . GT 0/0 0/0 11 48245185 . C G . PASS FL=0.34;FLG=0.1,0,0.9;FLA=88.4;FLR=99.0,88.4;INT=0;INTG=0,1,9;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta;STG=alpha,beta,gamma GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 11 48245185 . C T . PASS . GT 0/0 0/0 11 48245186 . C G,T . PASS FL=0.34;FLA=88.4,88.4;FLR=99.0,88.4,88.4;INT=0;INTA=88,11;INTR=99,88,11;F1;ST=alpha;STA=alpha,beta;STR=alpha,beta,gamma GT:FL:FLA:FLR:INT:INTA:INTR:ST:STA:STR 0|0:0.34:88.4,11:99.0,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:88.4,11:99.0,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma 11 48245186 . C T . PASS . GT 0/0 0/0 11 48245187 . C G . PASS FL=0.34;FLA=88.4;FLR=99.0,88.4;INT=0;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0:0.34:0.1,0:88.4:99.0,88.4:0:0,1:88:99,88:alpha:alpha:alpha,beta:alpha,beta 0:0.34:0.1,0:88.4:99.0,88.4:0:0,1:88:99,88:alpha:alpha:alpha,beta:alpha,beta 11 48245187 . C T . PASS . GT 0 0 bcftools-1.21/test/norm.merge.4.1.out000066400000000000000000000003351467060157400173450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T,CTT,A,CAA . . . 1 2 . C , . . . bcftools-1.21/test/norm.merge.4.2.out000066400000000000000000000003531467060157400173460ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T,CTT . . . 1 1 . C A,CAA . . . 1 2 . C , . . . bcftools-1.21/test/norm.merge.4.vcf000066400000000000000000000003051467060157400171520ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T,CTT . . . 1 1 . C A,CAA . . . 1 2 . C . . . 1 2 . C . . . bcftools-1.21/test/norm.merge.out000066400000000000000000000114041467060157400170430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 FAIL1 INDEL;AN=4;AC=2,2 GT:DP:FGS 1/2:1:A,BB,CCC,EEEE,.,FFFFF 1/2:1:AA,BB,CCC,EEEE,.,FFFFF 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 5 id0001;id0002 TGGG TG,TGGGG . PASS INDEL;AN=4;AC=2,0 GT:PL:DP 0/1:1,4,6,7,.,10:1 0/1:1,4,6,7,.,10:1 20 5 . TGGG TAC,AC . PASS INDEL;AN=4;AC=2,0 GT:PL:DP 1/0:1,2,3,11,.,15:1 1/0:1,2,3,11,.,15:1 20 59 id0003 AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,.,5:1 1/2:0,3,5,3,.,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C,G 0 FAIL1;FAIL2 INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . A C,G 999 PASS INDEL;AN=0;AC=0,0 GT:PL:DP ./.:0,0,0,0,.,0:0 ./.:0,0,0,0,.,0:0 bcftools-1.21/test/norm.merge.strict.out000066400000000000000000000114031467060157400203510ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP:FGS 1/2:1:A,BB,CCC,EEEE,.,FFFFF 1/2:1:AA,BB,CCC,EEEE,.,FFFFF 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 5 id0001;id0002 TGGG TG,TGGGG . PASS INDEL;AN=4;AC=2,0 GT:PL:DP 0/1:1,4,6,7,.,10:1 0/1:1,4,6,7,.,10:1 20 5 . TGGG TAC,AC . PASS INDEL;AN=4;AC=2,0 GT:PL:DP 1/0:1,2,3,11,.,15:1 1/0:1,2,3,11,.,15:1 20 59 id0003 AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,.,5:1 1/2:0,3,5,3,.,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C,G 0 FAIL1;FAIL2 INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . A C,G 999 PASS INDEL;AN=0;AC=0,0 GT:PL:DP ./.:0,0,0,0,.,0:0 ./.:0,0,0,0,.,0:0 bcftools-1.21/test/norm.merge.vcf000066400000000000000000000125611467060157400170170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06;XRI=1111,2222;XRS=AAA,BBB;XAF=1e+06;XAI=1111;XAS=AAA;XGF=1e+06,2e+06,3e+06;XGI=1111,2222,3333;XGS=A,B,C GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1 105 . TAAACCCTAAA TAACCCTAAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,500000;XRI=1111,5555;XRS=AAA,DDD;XAF=500000;XAI=5555;XAS=DDD;XGF=1e+06,500000,9e+09;XGI=1111,5555,9999;XGS=A,E,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC 999 FAIL1 INDEL;AN=4;AC=2 GT:DP:FGS 1/0:1:A,BB,CCC 1/0:1:AA,BB,CCC 2 114 . TC TTC 999 PASS INDEL;AN=4;AC=2 GT:DP:FGS 0/1:1:A,EEEE,FFFFF 0/1:1:AA,EEEE,FFFFF 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC . PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:1,2,3:1 1/0:1,2,3:1 20 5 id0001 TGGG TG . PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:1,4,6:1 0/1:1,4,6:1 20 5 id0002 TGGG TGGGG . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,7,10:1 0/0:1,7,10:1 20 5 . TGGG AC . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,11,15:1 0/0:1,11,15:1 20 59 id0003 AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:0,3,5:1 1/0:0,3,5:1 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:0,3,5:1 0/1:0,3,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C 0 FAIL1 INDEL;AN=2;AC=0 GT:PL:DP:FGF:FGI:FGS:FSTR 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 20 275 . A G 0 FAIL2 INDEL;AN=2;AC=2 GT:PL:DP:FGF:FGI:FGS:FSTR 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . A C 998 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . A G 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 bcftools-1.21/test/norm.out000066400000000000000000000115461467060157400157540ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTA T,TAACCCTA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS INDEL;AN=4;AC=2;END=191 GT:DP 1/0:1 1/0:1 2 101 . A ATT 999 PASS INDEL;AN=4;AC=4;END=101 GT:DP 1/1:1 1/1:1 2 114 . T TTC,TT 999 PASS INDEL;AN=4;AC=2,2;END=114 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 5 . TG CT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . A . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 84 . G T 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . T A 999 PASS AN=4;AC=2;END=95 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2;END=100 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . C CAA,CAAA 999 PASS INDEL;AN=4;AC=2,2;END=273 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 273 . C CAAAAAAAAAA 999 PASS INDEL;AN=0;AC=.;END=273 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 273 . C CAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C,G 999 PASS INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 17 . CA C 999 PASS INDEL;AN=0;END=18 GT:DP ./.:0 ./.:0 4 25 . T TT,* 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 36 . TC C,TT,TTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 21 . A AAG 999 PASS INDEL;AN=0;END=21 GT:DP ./.:0 ./.:0 bcftools-1.21/test/norm.phased-join.1.out000066400000000000000000000003761467060157400203120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 1 . A C,G,T . . . GT 3|2|1|0 bcftools-1.21/test/norm.phased-join.vcf000066400000000000000000000004621467060157400201160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 1 . A C . . . GT 0|0|1|0 20 1 . A G . . . GT 0|1|0|0 20 1 . A T . . . GT 1|0|0|0 bcftools-1.21/test/norm.phased-split.1.out000066400000000000000000000004621467060157400205020ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 1 . A C . . . GT 0|0|1|0 20 1 . A G . . . GT 0|1|0|0 20 1 . A T . . . GT 1|0|0|0 bcftools-1.21/test/norm.phased-split.vcf000066400000000000000000000003121467060157400203040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample 20 1 . A C,G,T . . . GT 3|2|1|0 bcftools-1.21/test/norm.right-align.1.out000066400000000000000000000007751467060157400203210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 7 897 . GGAATTAAGA G . . . 7 910 . G C . . . bcftools-1.21/test/norm.right-align.2.out000066400000000000000000000010221467060157400203040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 7 900 . ATTAAGAGAA A . . ORI=7|897|GGAATTAAGA|G 7 910 . G C . . . bcftools-1.21/test/norm.right-align.fa000066400000000000000000000720131467060157400177330ustar00rootroot00000000000000>7 7:154955-184155 TGAGGGCTGAGGTGACCCTTGTCTCTGTGTTCTTGTCCCCCCCAGCTTGTGGAGCCTCTT ACACCCAGTGGAGAAGCTCCCAACCAAGCTCTCTTGAGGATCTTGAAGGAAACTGAATTC AAAAAGATCAAAGTGCTGGGCTCCGGTGCGTTCGGCACGGTGTATAAGGTAAGGTCCCTG GCACAGGCCTCTGGGCTGGGCCGCAGGGCCTCTCATGGTCTGGTGGGGAGCCCAGAGTCC TTGCAAGCTGTATATTTCCATCATCTACTTTACTCTTTGTTTCACTGAGTGTTTGGGAAA CTCCAGTGTTTTTCCCAAGTTATTGAGAGGAAATCTTTTATAACCACAGTAATCAGTGGT CCTGTGAGACCAATTCACAGACCAAAGGCATTTTTATGAAAGGGGCCATTGACCTTGCCA TGGGGTGCAGCACAGGGCGGGAGGAGGGCCGCCTCTCACCGCACGGCATCAGAATGCAGC CCAGCTGAAATGGGCTCATCTTCGTTTGCTTCTTCTAGATCCTCTTTGCATGAAATCTGA TTTCAGTTAGGCCTAGACGCAGCATCATTAAATTCTGGATGAAATGATCCACACGGACTT TATAACAGGCTTTACAAGCTTGAGATTCTTTTATCTAAATAATCAGTGTGATTCGTGGAG CCCAACAGCTGCAGGGCTGCGGGGGCGTCACAGCCCCCAGCAATATCAGCCTTAGGTGCG GCTCCACAGCCCCAGTGTCCCTCACCTTCGGGGTGCATCGCTGGTAACATCCACCCAGAT CACTGGGCAGCATGTGGCACCATCTCACAATTGCCAGTTAACGTCTTCCTTCTCTCTCTG TCATAGGGACTCTGGATCCCAGAAGGTGAGAAAGTTAAAATTCCCGTCGCTATCAAGGAA TTAAGAGAAGCAACATCTCCGAAAGCCAACAAGGAAATCCTCGATGTGAGTTTCTGCTTT GCTGTGTGGGGGTCCATGGCTCTGAACCTCAGGCCCACCTTTTCTCATGTCTGGCAGCTG CTCTGCTCTAGACCCTGCTCATCTCCACATCCTAAATGTTCACTTTCTATGTCTTTCCCT TTCTAGCTCTAGTGGGTATAACTCCCTCCCCTTAGAGACAGCACTGGCCTCTCCCATGCT GGTATCCACCCCAAAAGGCTGGAAACAGGCAATTACTGGCATCTACCCAGCACTAGTTTC TTGACACGCATGATGAGTGAGTGCTCTTGGTGAGCCTGGAGCATGGGTATTGTTTTTGGT ATTTTTTGGATGAAGAAATGGAGGCATAAAGAAATTGGCTGACCCTTATATGGCTGGGAT AGGGTTTAAGCCCCTTGTTATTTCTGACTCTGAAACTTGCATTCAATTCACTCCACCAAG TTATCTCATCTTTGAAATGGCTTTTTTTAAAGGTGCCTAGAATATGATGGCGTGCAGTCT ATAAACTGTTGCCCACCTTCTGTACTTTCTCTCAGAATAATTCACATTCTTCTCCAGTGT CTGTTGATTGTTACTTTGTGGAATAAGTTCTTGGAAAATTCCACAAGATTATTGTTATCT TCTTACTACCAATTCTATTGAACTTTCTCCACCTTCTCTGGGCCTTCCCCAGCCAGTGGT GGGAAGATGCTGGCTGGAGTCTGACAGAGCCTCTTCTACACTGGCCTGGGCTTGCTGTGA GTTGGTGGAAACCTTTGCTCTTGTCCCAACACAGAGCAAGTGAAAGAGGAGGTCAAGGGG CTCAGGCAGCGGACTAGGGAAGCAGAATCGAGGAAAAGGAAAAATGGCTGACTTATTACC TCAAAACTCTAGAGAATTTAGTTGATCTTACAGCCAAGAAGGACAAAAGCCAGAGAGTAA TATCCTCCGCCTCATGTCTAACCCACAGAATACATAGCAAGTAAAGAGAACATGGGCCTT TATAAAAATGTCTTAAGATACAATTTTTTAATTGGAGGAAATCTACAGTTTAATTTTCTC TGGGCAGCTTTTCTTCCTTTTATTATAGTAGGGGAAATCCCATGTTGATATACTTCTAAA TGAAAGATGATGAATTGATATAATACAATAAAAAATCTGTAAAATTGATGATATACTTAT CAAGAAAAATTAGCTTTCATTTTAACGGTTTACAAATTGAGTCAAGTCCTAGTAACAAAA TGTTAAGTCTATTAACATAACCACAAGAAATACAGGAAGACGGGCAATCTGTGAAGCCTT TCACTTACAATCTCTGGCCCCTCACCTGTGCTGTGTAGGAAAATCTTTGTGCACAATTTG CTTCCTTAATTCATTTTTTATTCATTCAACACATTCTAATAAATTATACAAAATCATGTT GAAATGTGAATTTCAGTGGTATTTATAAATGCAGTGTGAGGAGGGTTTGGATGTATTCTA AGACAATAGTTGTGCTTTGGGAAGGAAGCAGTGTTCACTGAAAAGTGCCCCCAGGACCTT TTAATTGGAGGAAATATGCTTCTGTGGAGTTGGAAATGGGGTAGAAGATAGATAAGGTCA AGGCTTAAAAGTTAAGTGCACCCAACATCTGAAGCGTCCATGGGCCTGGCATGGTGGCTT TCGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATCCCTTGAGCTTAGGAGT TTGAGACCAGCCTGGGCAACATACTGAGACCCAGTCTCTACAAAAAATAAAAAATTAGCT GGGTGTGGTGTCTCATGCCTGTAGTCCCAGCCACTCAGGAGATGGGAAGATGGCTTGAGT CCAGGAGATCTAGGCTGCAGTGAGCTAAAATCTCACCACTGCACTCCAGCCTGGGTGACA AAGCAAGACCCTGCTCAAAAAAATAGTTAGATATAAATATTAATATAGATACCTATATAT ATCTGAATATAGATATCTATATATACTCTGTATATAGTTATTTAGATATATAAATATATA TGATATATATTTAGAGAGATATATATTTAGAGAGATATATATTTAGAGATTTATATATAT TTTATATATATTTAGAGATATATATCTCTAAATATATATCTCTCTCTAAATATATATATA TCTCTCTCTAAATATATATATATCCCTAAATATATTAAATAAATAAAAGAAATAAAAGAA AGCTCAGTTTGGCCTCCTGCTTGTCCTGTCTCCTCATCCCCTCTTCCCCCTCCATCATTT TATTTCCTTGCCCCATGTTTCTTCACTGCGGCCATGTCCCCCCTCCTCTCCAATGATGGA TGTCATGTCTGCTGCAGTCAGAGGGCGACAAGCCTGGAGTGTTCCCTGAAGCCTGTGGTT TGTGGTTTGTCCTGCAGCTCAGGCTGCCCAGGCCTCACCAGCAATCCTGGCGGGCAGGGC ACCACACTGGGATGGAGAGGGGGAAGCTGGAGGAGGCACTTTCTGGTAAAGAAAGCAAAA GCCAGCAGTGCCCAGGCCAATTTCAACAGGGAGTTAAATAGCACCTTAATCCTGTGGCAG GACAGCTCATGGGGCCATGTGTGCTCTTAGAAAGACTCACATGCACGCATGCACGGCAGC AATGACTCCATACTCACGTTCCCCTGCAGACACCAGGCCCCCACAGCCGGCACACACACT GCAGCCCCAGTTCCATGTTGCTAGCAGTGGCTTAGTGAATGAGTAAAGTTCTTAAAATGC AGGGGACACCTGCCCTTCATTCATAAGGCTGGACGTACACCTCTCCTTAAGGAGTTCAAG AGCTAGTGGAATCCCAATTCATACGGTAGAGCCATTCACAGATGAGAGAGACAAGCCAGA AGGAAGGAACCAAAAGTCATGTCAGCAGTTAGGACAAAATAACAGGCTTTCAAGGTCACA AAGCCTCAGGGACACTCCTGCGGTGGGACTGGGCTAGGAGCCATGGGGGCTCCAACTGTG CGCTCTGCCTGCCAGCCTGTGGGTGCTGGGGCTCCACGAAGATTGTTGTGGAATACCAAG CATGCTTGCTGTAGGTCACGGTGCACGTTTACTACTTCCAAGACAAACAGCCGAGAACAA AGCTCGCTTTAGCTTCTGCGTACACCGAACGGGACACACGACTGAACAGCGTTCCCATTG TGCCTGCTGGGTGGGGAGGAAGTGATGGCCCAGTGGGTCTATCAGATGTTAGTAGGATGG GGCCTGGCGGGGCTCCAGGCTCTGTGTGGCCGACACCCACGCCCCCCGCTCTGCTCCCCA TTCCCAGCCCCAGGTCAGCCCTGCGAGGCCCTGCAGCAGATGGGCTGCTCAAACTGCTCT GGTTTGCAGATTTTTCTTCCCTCTCAAATGAATACAATATGTTTTCAAGTCTCAACCAGA TCTTGAGAAAATAGGAAGAGCCAGAGGGTTTCTTTGGTGTTATGGTTGTACAGCTTCCCA GACTCCGGGGGAGAGATGTGATTTGTGCTTTCTGGCAATCCCATGGCGTATTAAATTTTC ATAGGCTTTCCAGTTTAAATTTAGGGTAGGCAATGGAAGGGAACGCAAAACAGATTTCTA GGTGTACTGTGTGTGTGTCTCCCACGTCTAAAGTCTGTTAACTGGAGCACCCAACAGGCC CCACAGGCTGCCTTCACACAGAGGACCTGGGGCGCCTCCGACCCATTGGGGTGAGCAGTG GGCCATGGAGGGAGCCAGGGTCAGGAGACCTGGTTGTGGGCCTGACCTGACCCTGCTCAG GGTGGCCTCAGGTGGGCCGTTCACCTCGTCAGCCTCAGCTTACCCTCTGACTACAGTGAC CTCAGACAAAATACGCTTCCTGGCCCTGTCCAGTTCTGACTTTTTATAAACAAGCACTTA TCCAAGTTAAAGGGATATTTTCAATATCTACTGAGTCCACAGATATTAAATATCTCCTCT CTTCTTTAAAATTGTGGCATTATCTTTAGAATATAAAAGGAAAATAACACACACTCTCCT TGAAAATAGAGAGCCTAAACACTCTGCAGGAAATATTTAAAGCTATAGTTTTTGTTTGTT TGTCTTGAATGCAAGTGGCCTGGACTTTGACTTGCTTTGAGTCTTTGACCTTCATGACTT CAGTACAGTTCAACCCTGACAGTTTTGAAGTAGGTATGTGCCTAGATCTGCCCTAGTCCC TGCTGGAATGTTGAAGAAGCAAAGGTCCAGGCCCTCAGAGCACTTGCCACGTACTTGCCA ACAGATACGGGGCGGAGACTTGAGTCAACGTAAGAGCAAGTGTGTGCCGGGTGATCCGAC ACTGCAGAGCGCCAGCTAGACCCTAAGCGTGTGCTAGGGGCTGACCAAGCCGTTCTTTCC TCAAAAACTTGGTGGGGAGGGTATTTTTAAAATCACACAAATATTTAAGTACAGATTATG ATGACTGCCTCAAAGCAGTGGCTCTTCAGCTTCATCAAGCTTCAGAGTCCAGAGGGTTTG TTCATATGGAAGGCTAGGCCTGTCTCCTGCATTTCACCCTCTTGGCCTGGGGGCGGGACC CAAGAATGTGTGGCTCTAAAAGGTTCCCAGGCAATGCTGAGGCTGCTTTCTGAAGGAAAA ACTGCAAGATACCAGGAGAGTTTCATTTAGATTGAAGAGTCGAGGAAGGCTCCTCTGAGA AAGAGTCTGCTAAGGAAGGAGGAGGTGGGTTCTGGGGACAGAGGTTCTCCCGTGGGTAAG GGTGGAGGGAAGCTCTCCTGGGGAGAAGGTGGGCAGGAGGACCAGAGGCTGGAGGGAGGA GGGCAGTCAGCCTCGGGGCTTCCCAGGAACAGGGACGGCCAGGGCAGGGTTTAGGGCAAG GAAAGCGTGTGAGCATATTTGTATTTTAGTAAATATTTACAGTTTGCCCTCCATGTCTGC AGTTTCATATCCATGGATTCAATCAACCACAATGAAAAACGTTGGGGAAAAAAATTGCAT CGGTACTGAACATATACGGACTTTTTTTCTTGTCATTATTCCCTAAACAATACAGCATAA CAATTATTCACATAGCATTTGCACTGTATTAGGTACTATAGGTAATCAGGAGATGCTGTA GATGGGAGGATGTCTGTAGGTTACACACAAATGCTGTGCCACTTTATATCAGGGGCTTGA GCATCCTCACATTTTGATATTTAAGGGAGGTCCTGGAACCAATTCCCCAGATACTGAGGG TCCACTGTCTGTGTCCCCTCGCCCCACCTTGCCTTTGTCTCCTGTCTCCTATCTCCACCC TGCCTCCCGCCAGCCTGTTGCTCCTGACCTGCCCGGGCACCCTGGAGCAGCACCCTATCT CAGAGCCTGGCTCAGTGTGTTCACTTCTGCAGAGAAACTAACTTGCCCAAGTCCACACTC AAAACATAGGCATTGCTGAGATGTGAAAAGCAGCTGTGGATGCTTTCTGCTACAGTCTGT GTGTTCTTTTCCATATCTGAATAAAAGGTCACCACCATTTGTATTTTAAAGAGAAAGAGA ATTTATGGGTGGAAATTGGGGATTCCCTCATTCTCAGTCAGACAGAAAAGAGGGCCCCAT TGTGTGCCTGATTGCAAATAAATTTAGCTTCCTCAGCCCAAGAATAGCAGAAGGGTTAAA ATAAAGTCTGTATTTATGGCTCTGTCAAAGGAAGGCCCCTGCCTTGGCAGCCAGCCGGAA TTAGCAGGGCAGCAGATGCCTGACTCAGTGCAGCATGGATTTCCCATAGGGAGCCTGGGG GCACAGCACAGAGAGACCACTTCTCTTTAGAAATGGGTCCCGGGCAGCCAGGCAGCCTTT AGTCACTGTAGATTGAATGCTCTGTCCATTTCAAAACCTGGGACTGGTCTATTGAAAGAG CTTATCCAGCTACTCTTTGCAGAGGTGCTGTGGGCAGGGTCCCCAGCCCAAATGCCCACC CATTTCCCAGAGCACAGTCAGGGCCAAGCCTGGCCTGTGGGGAAGGGAGGCCTTTCTCCC TGCTGGCTCGGTGCTCCCCGGATGCCTTCTCCATCGCTTGTCCTCTGCAGCACCCACAGC CAGCGTTCCTGATGTGCAGGGTCAGTCATTACCCAGGGTGTTCCGGACCCCACACAGATT CCTACAGGCCCTCATGATATTTTAAAACACAGCATCCTCAACCTTGAGGCGGAGGTCTTC ATAACAAAGATACTATCAGTTCCCAAACTCAGAGATCAGGTGACTCCGACTCCTCCTTTA TCCAATGTGCTCCTCATGGCCACTGTTGCCTGGGCCTCTCTGTCATGGGGAATCCCCAGA TGCACCCAGGAGGGGCCCTCTCCCACTGCATCTGTCACTTCACAGCCCTGCGTAAACGTC CCTGTGCTAGGTCTTTTGCAGGCACAGCTTTTCCTCCATGAGTACGTATTTTGAAACTCA AGATCGCATTCATGCGTCTTCACCTGGAAGGGGTCCATGTGCCCCTCCTTCTGGCCACCA TGCGAAGCCACACTGACGTGCCTCTCCCTCCCTCCAGGAAGCCTACGTGATGGCCAGCGT GGACAACCCCCACGTGTGCCGCCTGCTGGGCATCTGCCTCACCTCCACCGTGCAGCTCAT CACGCAGCTCATGCCCTTCGGCTGCCTCCTGGACTATGTCCGGGAACACAAAGACAATAT TGGCTCCCAGTACCTGCTCAACTGGTGTGTGCAGATCGCAAAGGTAATCAGGGAAGGGAG ATACGGGGAGGGGAGATAAGGAGCCAGGATCCTCACATGCGGTCTGCGCTCCTGGGATAG CAAGAGTTTGCCATGGGGATATGTGTGTGCGTGCATGCAGCACACACACATTCCTTTATT TTGGATTCAATCAAGTTGATCTTCTTGTGCACAAATCAGTGCCTGTCCCATCTGCATGTG GAAACTCTCATCAATCAGCTACCTTTGAAGAATTTTCTCTTTATTGAGTGCTCAGTGTGG TCTGATGTCTCTGTTCTTATTTCTCTGGAATTCTTTGTGAATACTGTGGTGATTTGTAGT GGAGAAGGAATATTGCTTCCCCCATTCAGGACTTGATAACAAGGTAAGCAAGCCAGGCCA AGGCCAGGAGGACCCAGGTGATAGTGGTGGAGTGGAGCAGGTGCCTTGCAGGAGGCCCAG TGAGGAGGTGCAAGGAGCTGACAGAGGGCGCAGCTGCTGCTGCTATGTGGCTGGGGCCTT GGCTAAGTGTCCCCCTTTCCACAGGCTCGCTCCAGAGCCAGGGCGGGGCTGAGAGAGCAG AGTGGTCAGGTAGCCCTGCCTGGGTGCTGGAGACAGGCACAGAACAACAAGCCAGGTATT TCACAGCTGGTGCGGACCCAGAAAGACTTCTGCTTTTGCCCCAAACCCCTCCCATCTCCA TCCCAGTCTTGCATCAGTTATTTGCACTCAACTTGCTAAGTCCTATTTTTTTCTAACAAT GGGTATACATTTCATCCCATTGACTTTAAAGGATTTGCAGGCAGGCCCTGTCTCTGAGAA TACGCCGTTGCCCGTCATCTCTCTCCGACAGCAGGGCAGGGGGTCCAGAGATGTGCCAGG GACCAGAGGGAGGGAGCAGACACCCACCCGGCCTGGGCAGGTCCTCCTCATTGCTTGCAT CCGCCTGGTTAGCAGTGGCAGTCAGTCCTGCCGAGTCATTCGTGAGGCGCTCACCCAACT CCAGGCAGATGTAAAAGGTGACCTACAAGAAGACAAACAAAAACATCTGGAGCGCTCTTA TGCCAGCATCTGCCCTTGACACCACCAGGCAGGCTGTTGCTGGGAGCCGTGGTGCTTGGG TAAGCTCCTTCCCATGGCAGAGCTCCTGGGACGCATTGTAGAAGCAGGGACCACCTCCCA GGATAACCAGATAGCAGCACACCCTGCACAGCCCCTTTTACTCCAGCATCATCGGGCATT GATATCTCAGCTGCAGCCACAGGCGGCCCCCAGCACCCCAGGAAGTGGGGAGCGCTCATG CTTCTCTGAGCACAAAAATCACTGAATATTTTTGCCATTCTCATGGTCATAACCCGGGCC ACAGAGTAGAACACTCCTATCACTGTTGTTAGACAGTGGTCCTGGGAGAGGGTCTTGTGT GCCTCGGATGCCAGGGCCTCTTTTTATTGGGAGGTGCTTGTTATTTCTGTGTGTGGCTGC ATTTGTTTCCCAAGACTGCCACAACAAATCATCACCAACTTGGTAGCTCAACATAGCACA GCTTTATTCCCTCCTGGCTCTGGAGGCCAGGTGTCTAAAAGGCCATGCTCCCACAATGGT TCTGAGGAGGATCCTTCCTGCCTCTCTGGCTTCTGGTGGCTCCAGCATCCCTGGGCTGTG GCTGCACCTCCCCATGTCAACCTCCGTCTTCACAAGGCCTTTTCCTGTGTCTCTGCAACC ACAGGCCCCTCTCCTTTCTCTTAATAAAGATACCAGTCATTGAGTTTGAAAATTGCTAAG AGAGTCTGTTGTAAATCTTCTTAGCACAAAAAAAAATGACAGATATGTGAAGTGGTAGAT ATATTAATTAGTTTGATTTGATCACTCCGCTATGTGTATAAATGTCAAAACAAACATTGC ACTCCATAAATATATATATTAAAAAAGATCCCAGTCATTGCATTTAGGACCCACCCTAAA TCCAGGATGATTTCATTTCAAGACTTTTAACTAGATTTGCAAAACCCCATTTCCAAATAA GGTCACATTCTGCAGTTTTGGGTAGACGTGAAATGTGGAGACACTGTGCAACCCACTGTC TTGGGGAGGGGGTGGTCAGCCTGGGGCAGATGTTGCTGGGTGTGGAGCTACATCCACTCA TGCCCTGACCTGGAACCCAGACCTGCTTCCCCAGCTCTCCTCCTGGTTATCTGAAGCAGG GAATGGAGAGCACTGCCCTCCTTGCCCAGGCAGTCTCTATCACCTGGTTTTAGTTTCTTC TTAGCACATATTGCCCCAGAATATCTGGTTGGTTTATGGCTTACTTGAGTTTGTGCCTAC CTGTCCCAACCGGGAGGTGAGCCCTGGCTATTCCCCAAACCCGGCCCTGCATGTGGGAGC TGCCCTTCCTCCGTTCATCAGAGGGGGCCAACAGTCCACAGCTGTTCTTAATCATCTCCC AGTAACCCCCAGCTCCACAAAGGTGACTCCTTACATGGTGGAGAGGTGGTCGGGCCATCC GTGTGAAATGTGTATGTGACCGTTTTCCTTAAGGGGCACGTAGTCTTGGCAGGTTTCGCT CAATATAGGATGAGCTCAGGACTCCAGTGGACTGTGGATTCAGATCTGGATTCTGGCGCA TTCGCCGTGTGAACGGGGGCACGTTGCTGGCCTGTCTGCGCCTCGTCTCCCGACTGTGGA GTGTGTTCTGCCCCTTGTCTTTCTGGGAGGTAGGGAGGGCAGTGAGCCCCTTCGCATCGC CCACCACAGGCCCAGCACATGGCTGATCCCCACTGAGTGTTCTTTTCCTCCTTTGATCCC CTTTGGCTGACCTAGGTTGGAGCAGCCACTAAAATATACCCAGAAACATCTTCCTAATCT ACATCTGTGCCAACCCTCATTCCCTGGCGCAGCATGACCATCACATGCCCGCCATTGTTC CTGATCTCTGCTGCTCATGACCTGCTCTCCAGCGCTCCTTCTCATGCTCACATTCCAGTT GGCCTGACCTAGATAAGTGGAGGTTTATTTGACCCCAAAAATTAGCCTTCTACAAACGAA TATAATAGTGTCCATTACAGAGAATAAACTTAGTGCGTGTCCCATTTAAGCAGAAGTTAC TGAAAGCCTGAGTTTAAGTTTCCAGGGCCTGAAAGTTTTCCATGACAGTTTTCTGCATAA TATTACCTACAATTTCAATCTGTTATTTAAAGCCATTCTTGTGTTTGTTGTACTTTGATT AGCTTTATTTTGATTTGAAGTCCTTTTACATTACGGGCAGTTAACGCTTTGTCTCTGTTA GATTTGCTTTTTAGTTCACAAGAGAAACCTCATTCCTCTGTATTTGAATAGTTGCAATGA TGGAACAGCTGTCCCTGGAGGGAAATGAAAACAGTGATTCCCCAAATTGTGACAATAGAA ATTTGCTCTTGGGTTACTTACAATGTATCTGAGTATTAAAAAATTTTCTTTTTAAACGTT TGAAGTAAAACTACCCAGAAACACTTAGTGGCTGACCAGAAACTAAACTCCTGGCATCCT CAAAATGGGATTTATTGGCTTATAAATGTCCTGTGTTGACTCACAAAGGCACAAACTATC TAGGTAAGTTTTCTTCTAAATGTTGATGGGAGAGCTGGCCACTGTTATGCAAGTTTCATT GTCCTGACTAAACTGCCAAAGAGATTACATAAAATTATATCAACTAGACAAAAGGAAAAA GGAAAAAAAACAGAGGTGTCTTGGGAGGAATCCATATGAGACCAGTAGACCATGAGAGAG ACATCCCTTGCCATCTACAAGGAAAATGGATTTTGTTCTCCATATGCAAAACCATCTCAG GAGCTTGCGGAGACACCACTTGCTTACTAGCCAGAAAGAGCAGGTGCCTCCTAAATTCCC CACACAGGAGCTCACAGTGGCTTTCATGCACTGGGATTAAGTTAGACTTAAGAAAGCCTG TCTACTCTTCCTGGGATTTACAAGCCAGCTAGTAAATCCCAGAATAAATCACACGGCACA GTCATCCAAAGATCCCGTCATCCGTGCCGTTTGGAAAGCCCTGCTCCTGTGCCACCCTCT CCCCGTGGAGCCTCCCATGCCCAGGACTGCAGAGTCCTGCCATTCAGACTGCAACTCATC TCACATTCTTCCAAACTATTTGGACAACAGAGCTTTCTCATCACCTAATGCAGATTACAG TCTCACAGAATTGAGTGTTCAGGCAGACACTGATGTGGTTCTGTAGTACAGCAAACAATA TCAGTTTACAGTCCTGAGGCCAGGCCTGGTGAACAACGCACGGTAGCGGTGGGGCAGGGT TCTCAGAATGAAACTGGCTTACACATGGCACTCTCTGACCACAACTGTATAAGCACCAAA CTACACTTAGTTCCATCTATGAGGTAAAATTTAATGCAGATGAACATCAAAGAAAACGTC AAAGGCTCCTTTTTACAAGTACGTGGGCTACTTAATTTGGTCCAAGTCCATTTTAAAAAG CCCTAGGTGCTTTCACGGCTCTGCTACTGACAAGAAGCCCCAGTGCCTGTGAGCTGCTAA TGGGAGGGAGAGGAAGATGAGCTGAGTGGGCCGGGCTATCCCGTCCACACCGGGAGACAG GGAAGGAGACTCCAAGCTGGTGGTGCCAGCACATTCCAGGCCACTCAGGCCTATTCCTAG GTGCCAGGTCACGAAAACCACGCTGACAGATCGTGCTGTGTGCGTGTCATAGCACACAAG CAGGACTGTGAGAGAGTGAAAGTGACACTGGGTGGAGCACTGAGGAAGGGCCACAGTGTG TTGGTGGAGATAGGCTGTCATGGAGAAGAGACCCTGGCTTGCTCTACATTGCTTCCAATG CAACTGCAAGGCAGGTCCCAGAGGGCTCCGGCCTTCGTCATCCAGGTTTGCTCCCTCCCC TCATGGCTTTCCCATCCTCAGATGAGGACTCGGCAGAGCCTACCCCTGCTGACTAACTGT GGCCCCAGGGTGGTGACTCAGCCCTGCACCTCCTGATCCCGTCTGCACTGGGCCAGAGAG GATGACTTACCCAGCACGTTCACATCACACAGCTTTGTGGATTCCTAGGTCCAAGGACCA GAGATTTCAGTTATGTGAGTTATTTTTTTTATTTGTTCTTGCGTATTCCACAAAGGGTCG CAGCTAAACTTAACCTAATGATCACTTTAGTATATCACTAAAAAGACAAAGCTCACAGTG CTGTTGAAGCACATTCATCATCTTTAGACATTTTGACTAGTTATTTCTTAAGCATTTACC TGCTAGTGTTAAGCATCACATGAAATACATATAGAAGTAAGACAAAATTTCTTATCTCCC CAAGTTTGCCAACAAATACAGAGCAGGAAGGGAAGCAGGTCAGAGCAGGAGGCGCAGCTA TAGTGAGGCCACCATGCAAGGCACAGGGAGGGTGAGCTCCAAGTTTGAATGGAATGGGTC TGTCAGCCAAGCCCCCTGGCTCTGGGAAGATAGCAGTGAACAAGCCAGATGGCCCCTCAC CCTCCAGAGCCGTGAGTCCTGCAGACCAAACAGCGTGACAGGTCCTTTCCCTGTCCAGGA GGCCTCTGTGGGTGAGAGTTGGCTGCGGACAGGGCGTGAAGGCACTTGAGGGTGGGGAAG TGACTCTGACTGGGAGATGCTGAGGACAGGGAGGAAACCACCAGATAAGGGACACTGGGG AGGAGGGGTGGACCCCTCAGGGCCAAGCACATGGAGCCTCATCACAAAGGCAAGATGGTG GCCAAATTCAAGGTCGCTGCAAAAGGAATGGAGAAGAGAGAATAGATTTGGCATTTGGAG GAAATGGTGACAATCATGAGCACCTACCCGGGACTCTCCATGGGTGCTATCTCTACATAA ACTCATTCCACCCTCTGATTAATCCATTCTACATATGGGGAAACAAAGGCATGCGGTGTT TACGTCACTTGCCAAGATCTCAGGATTTGATCCAGGTGGCCTGGTTCCATGGTGCAGCCT CTCAGCCTGCATGGATGCCCCAGCTCAGAGCATGACTCTCAGGACAGGGGTCCCAGCAGC CCTCCCTCCCTGAGCAGCAGGGTGCCCGTGCTGCACCACTTCTGTCTAGGAATAGGACAT TCTGACACTTTCCTGCCTCTTCCGAGGTCTAGCACTTACTCTATGCCTGCCTGGGAAGGT GGCAAGCTGGCCTGAGGAACAGACTCTTCCATTTTTTAGGGAGCTCAAGGCCACAGATGC TCTGAGATCTGGAGTCCAGAGACAGGAGCGGAGGCTTCTCCTGGTGACCACTCTGCTTAA AAACTTCATCAGATCCGTAGTTTCAGAGCCCCCCTGAACCCCATCCCTTACCTCTACCAG TTGCAGGTGGGTCTCTGGGGTGGGGCTGCCCTCCCCACCAGCACCCCAAGGGCTAAAAGG TTGAGGGGAGAACACCATCATTTGTACAGGGGGATCCTGGAAGATGAGGCCTGAGAAAGC CCTGCGGGGCCCCTCACCTTCTCCCTAGCTGTGGCCAAGAGTGTCTGGCCTTGCCTGCCT CAGGACCAGCCCAAAGTGGAGGTGAGAGGTGAGCCCCAGCCCCCAGGGGAAGGGTGATGG TGGTCTTGGTCTCAGCATGGTTCTGGTAGAGGTGGGTTATTTTGAAGATGATGAACCTTA AGCCTCTTTCTGATCTTGCTTTAAATAAATACTTCTGAACAACAGCAACAACAGAATAGT GTTGATAGGAAAGCCCTCCACTCCACCAGAACCACGCGGCCTTCTCGTCCTCCCCTCCTC CACTTCCTTCCTAAGTCACTGCTCCATGAGCTCTTCCACAGGAGATTTACAAAATAGAAC ACAAACAATCCAGTTCCCGCCTCTCACTCTGAACTCCTCCCAAGACTCGTGGGGTGCGGC AGCCCCTGGGAACACCCAGCCCTTCAAGGTCAAACACAGCCCCCGCCCCTCACTCTGGGG TACCCTGCCAGAATAAGCCCCGACAGCCATGTGGAGCAGAGCCTTCTTTTTTGTAAGTGG AAGTTCCAGGCTGGCTTTTCAAATCCCCTTTTAACCTCAGTGCTGTATTTCAAAATTCAT TCCAGTTTTCCTGTAGTAATTAACAAAAATAAATATTTTAATTTCAATTAAAGTGAGGGT CTCGGAGAAGAAGCAGGAACTGAGTTTCCTGAGAGGCCCCGCTGAGGCTTTGTTGATATT TCTTCCTGCGACCTCTGCTCGGACCCTGGGAGCTCACAGGCCGTATCGCAGCTCTTATCT TTGGGGACCAGTTAAAGCATAACTGCGCCAGGCACAGAGTTGTCCTTTCAAATGTGCCGG CAGTGGGACGGAGACCCATGCGTCAAGTCTCCTCTAAGTTCACATGGGATTCTCTCCTTG TCCCAAAGCTGTCTCTGACTTAAAACCCTCCAACTGATTACCTGAATTCCAGAATATGTC CTGTGCTCTCTGCCCTTTCCCACGCCTTTGGTGAAGACCGGTGTTCTGAGGAAACAGACA CTGTGTAGAAATGGCTCAGGTCCTTTAAAGCCCTGGTGTGAGGAGTGGGGAAGGGCTGGG CCAGAGGTCAGCTGGATTTGTTAGATTGACAGAGTGACGCGGACTTCCCCAGAGGCACGG GACCAAGGTGCATGCTCACGCTGTCTCATGCTCTCACACATAATGTGTGTGTGTGTGTGT GTGTATATATATATACACATATACATATATATATATACACACATATGCATATATATAAAA CCCCAAGCAGCCTCTGGCTTAGCAGGTGCATTTCCCAGCAGGGCAATTAAAGCCATGGTC CCAGTAGTGGTCTTGGGGTCTCAGGGTATTTGGTCTGTGCAGCCACATGCTTCAGTCTCT GGACCCCAGGTCATCTAACGAGGTGGTCGTGTGGGGACTGGGATAGAAAAGGTGTCTGCA CGGACGTGTGTGAAAGGGCTGGCACATCGCCAGTGCTCAGCACTGTCAGCTGCTATCACC AGTCATTCAATCATTCATTCATTCAGTTGTTCATTCTTCAACAGGCCGTTTTAAAAATGT GCCCAGTATACCAAAATCTCCGCTAAGCATTTAAAGAGGCAGAATGAAAGTTAGCAGTGG TGGTGAAACGAAGCTGGGAATGTGCTCTGAGGGCCTCCTTGTGGGCTTAATGAATATGTA GAAACCACGCATTTTAAATAGAGAGGGAGAAAGGGAGAGGTTCCTGGTCCTCTGCATGGG GACTTGTGTGTGGCTCTTTACTGTAGGCCTGTGCCACTCCTGCTCAACAGCTACCACAGA GGACGCCTTCAACAAATGTGAAGAACGAACAAAAGGTACAAATGTGAAGAACGAACAGGG TAGAAAGAAAGGAGAAAGCAAGGGTGAGGGTGAGAAATCAAGGGACAGAGAAGAGAGAAG AGGAGATAGCCTGGGAGTTCACACAGCCAAGAAGGTAGACACTCAGTTGAACCAGCAAGA GGCTGAGCCTAACTCTCCCTTTCGAATGGGCAGGAGTTCATGATATTTAATAAACAGAGG CCTTGCTCTGTAAGAGACAGGGTACCAGGCAGAGAGCAAGTCAGCATCGCAGGAGTCAAA CGAGGCAGACAGCGGGGGCAGGGAGCTTGCCTCTGAAGGAGACCCAGGCTGCCAGAGTAG CAGGGAGTCTGGGCCAGTCCTCTTTTGGGAAGCGCTTCCTCGGCTTCTGCCCCCCCTCTC CTCTCCCTTTCCACCCACCATCCTGACATAATACTTCCTAATCTGGAAGTGTTGTCCAGA GAAGAACCTGCTCATTTCCTCTTAAGTAGGCAGGGAAGCACTAACGTCCAGCAGCATCGG AAACCCGTAGGAGCGCTCTCGGCAGTGCAGGGTGAGGGGACAGTCCATGTAGTCATGAGA CGTGGGTGTCAGGCAAGCGTCTCTTTTCCAAAAGAGAAAAACATTAAAGGCCTCACAAAC GGCGCCCAAAGACTAATTCTGCATAGCATCTTTGCGAGACCCTAGGTTCTTATGATGACT GGTTTTGCCTGAGAAAGAAAAAATTTTAATTTTGCTCTGACATGCCAATTCAACAAATCA TTTTCACATAATATTCATGCAAAAAAAAAACAATTTGCCAGAAAACTTGGGAATCCATCC ACATCTACAGCTTTTCCCTGCAGTCACACTACAGTGGGATCCCTCCATACAGGAGCGGCA GAGTGGAGCAGGCTAGAGATGCCTGTTTGTTTCTGTTTGCTGCACCGCAGCAAGCATTTC TGTCGTGCCCACTCTGTACTAGAAAGTACATGAACATCAGCCATAAAGGGAACTAGAAAG GTGGCCCACCCTCTTGGTGGAGAGAGAAGAGAGTGTGGTAGAAACAATAATAAGAAGTCT GCAGAACTTGACCCCTCCCAGCCTCTCCCACCTGCCAGCCTGGCCCTTGCAGAGAGATGC AGGCTGCCATTCTTAGGCCAAAGCCTGGGACAGTTGGGCTCAGCAAGGTAGGCATCCGTC AAGCAAGGAGGAGCAGGGGTCAGCAGTGACCCCAGCAGCCAGCAGGGAGAAAGGTGCATG TGACAAGGACACCAGAGGCCGTGGGTCAGGATCAGCCAGGGTCAGGGTAGCATTTCTAGG AATTCACTCTGTTGGGCGCTGTGCTGGCTGCTTCTCACATATTATTCCTTTCTTACTCTC AGAGCAGAGATTTCAATTGCAGCGAGATTGTGGAGGCAGCCAGGGAGGTGGGGAGGGTGG TGTCTTCTAAAAGCATTTTCAGTATCCATGTGGTTTCAGTAATAATAATAATAATAAACC AGTGAAAAGTAAAACAGGACAAAAATCTTCATAGGCAGTGAACCATATCAGAGAGTCCAA GAAAGCACAATGAGAGTGTGGCTTAAAAACCCTGAACGACATTCCTTTGCACCAGCTTGG TGAGGAGGGCATGGTCCCCGCCACCCCCCACCCCCACTTTGCAGATAAACCACATGCAGG AAGGTCAGCCTGGCAAGTCCAGTAAGTTCAAGCCCAGGTCTCAACTGGGCAGCAGAGCTC CTGCTCTTCTTTGTCCTCATATACGAGCACCTCTGGACTTAAAACTTGAGGAACTGGATG GAGAAAAGTTAATGGTCAGCAGCGGGTTACATCTTCTTTCATGCGCCTTTCCATTCTTTG GATCAGTAGTCACTAACGTTCGCCAGCCATAAGTCCTCGACGTGGAGAGGCTCAGAGCCT GGCATGAACATGACCCTGAATTCGGATGCAGAGCTTCTTCCCATGATGATCTGTCCCTCA CAGCAGGGTCTTCTCTGTTTCAGGGCATGAACTACTTGGAGGACCGTCGCTTGGTGCACC GCGACCTGGCAGCCAGGAACGTACTGGTGAAAACACCGCAGCATGTCAAGATCACAGATT TTGGGCTGGCCAAACTGCTGGGTGCGGAAGAGAAAGAATACCATGCAGAAGGAGGCAAAG TAAGGAGGTGGCTTTAGGTCAGCCAGCATTTTCCTGACACCAGGGACCAGGCTGCCTTCC CACTAGCTGTATTGTTTAACACATGCAGGGGAGGATGCTCTCCAGACATTCTGGGTGAGC TCGCAGCAGCTGCTGCTGGCAGCTGGGTCCAGCCAGGGTCTCCTGGTAGTGTGAGCCAGA GCTGCTTTGGGAACAGTACTTGCTGGGACAGTGAATGAGGATGTTATCCCCAGGTGATCA TTAGCAAATGTTAGGTTTCAGTCTCTCCCTGCAGGATATATAAGTCCCCTTCAATAGCGC AATTGGGAAAGGTCACAGCTGCCTTGGTGGTCCACTGCTGTCAAGGACACCTAAGGAACA GGAAAGGCCCCATGCGGACCCGAGCTCCCAGGGCTGTCTGTGGCTCGTGGCTGGGACAGG CAGCAATGGAGTCCTTCTCTCCCTTCACTGGCTCGGTTTCTCTTAGGGACCCTCACAGCA CTAAGGGGTGCGCGTCCCCTGTCAGGCCCTCGAATGCCCTCCCACAGCCAGGCCCCTCTG AGGTTTCACTCTGGCCTGCTTGGCTCCTAGCAGCCACCAACCCATGATGCTGGGCCCTGA AAACACACGCAGACCTGGATGAGTGAGGCCACTGGGCACAACCAGGGCTCCCAGCTCACC AGAGCAGCCTGGGACACAGAGGGTGCTCAGAAACCTACCAGAGCAGCCCTGAACTCCGTC AGACTGAAATCCCCTGTTGCCGGGAGGAGGCGCCGGGCCTGGGGGACGGGTCCTGGGGTG ATCTGGCTCGTCTGTGTGTGTCACTCGTAATTAGGTCCAGAGTGAGTTAACTTTTTCCAA CAGAGGGAAACTAATAGTTGTCTCACTGCCTCATCTCTCACCATCCCAAGGTGCCTATCA AGTGGATGGCATTGGAATCAATTTTACACAGAATCTATACCCACCAGAGTGATGTCTGGA GCTACGGTGAGTCATAATCCTGATGCTAATGAGTTTGTACTGAGGCCAAGCTGGCTTTTA TTGTTAGTTAATTTACATTATATCCTCTGACATGCAAGTATTTTCTTTCGAGATAATGAC TAATGATAATGTAATCATTGCTGTCTATCTATTGTACTGAGAAAACACGGCAGAGGAAAT CGAGTCCAGCTGCCGTCCAAAAGTCACTGGAGATTGCAATGAGCTCGTCTGGCAGGGTGG GGGGTATGGGAGGGAAAGAGCTTAGGAAACGGCTCTCCCTGCAAAGTCCAACCAAACTTT AACGTTAACCAAACCATTAATGTTGCCATGAATTTGAAGTGAACCAGAGGGAGGTGGCAG AAGAAGCTTAATGGGGAATAGTTCCGGTAGAGAAATGAGGCTTAAGATGAACTACCCTGG CCCTTATGTGTCAGAGAGAACGGCTTGACAAACACACACTGAGGATGTCTGCAGGGATAA AAGAAGAAAGGGAGATGACCCTTGCTTCTCGCTCTCGGGAGGACCATCTGGTCCGGCCCT GGGGATTCTCTGTTTCCTCTTCTGAATCCCAGTGTTGCCCAGCACTGGCCTGTACCCATC CTCACGAGGGCCGCTCTCCTCACCCGGCCCTAGGTCCCTGCCCTGTCCTGAGCCTACAGG GGCCTCCCATGTTGAGAAAGTGTTGCTGACACATTGTCTCTGACCGCTGTGCCAGGCATT TTCTGCTGAATTACCGCACTTGGTCCTTGAATTTCACCCAGCAACTTACTGAAAGGCTGG AACCCATGAACCTACCCCTTCACTGAGGAAAATAAGTTACCCCAGCCATCTACAGCGACA GGAGCAAGGGAGGAGTCGCCTCACCTCTCTAGAAATGTGTATTTGAGGAGAACACTATTG AAATGAATTTCCAAGAATAATCTAGTCAGTATTACAAAAGCAAAATTATTTGGGATATCG TCCTTTTTTACTTAGTATTTTTTCTTTTTCCTATAGCATTATTAACTTTCTGATTTTCCA AATACATACACATTTTTAAATTTCCTGAGTCTTTATCTCTTCTGTTAAAATGTAAGATTT ATGATACAAAGGCAGAGATTTGTGTCCATGAATAAGTGAAGTTTGGTGTGCACCTGTGAG CTGAGCCACCTCAATTAATGGAACAGATAAGGAAATAAAGGTCTGCTGATGCATTGTTAT TTACAGCCATTTTCAGAATGTATCTCCTCTCCACGAGGGAACTGCAGGGTCCTGCCCCAA GCCATTTATTTTGTCCTCAAGCAGCCCGCCCCTCCCACTCCAGGCACAGCCCGGTCTCCT GCTGGTCTCCCCTCTTCCCACTTGCTCCCCCTCATCTATGCTCCAGACAGAGGCCACATA TATTTTTTAACTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCCCTGTCACCCAGGCTG GAGTGCAGTGGTGCAGTCTCGGCTCACTGCAACCTCCACCTCCCGGGTTCAAGTGATTCT CCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACACCACCATGCCCAGCTAATT TTTTGTATCTCTAGTTGAGACAGGGTTTCACTATGTTGGCCAGGCTGGTCTCGAACTCCT GACCTCATGATCTGCCCGCCTCGGCCTCCCAAAGTGCATATTTTTTAACTTTATCAGACT TTTCATTCTCTGCTCAACATCTTTCTTTGGTCCTCCAGGTATGTTCAGATAAAACCTGAG CACCTGGCCATGACTGATGGGTTGCTGGGCCATCTGGCCCTGGCAACTCTCCCGTCCACC AGGTCCCCCTCCCGTCACGCTCCAGGCATAGCCTGTGTGTGCCAGCGCAATGCCCACACT CCATGCACAAGTGGAAGCCCTCTCAAAGTCAGTGGCTTAGTGCCTTGATGTGGTCACACC CATTCTCAGGAAGTCCGTTCCCACTGAAAACATTGTGTGTTTTCAACATCATTGAGGCTG CCACGGCAGATTATAATCACTGGCCTAGGCAGCCCACTGGAACTACCAGACCATGAGCCT GAATTTTTTGTTTAAAAATCATATCCTGTTTTCTCTACTCTCTAGTCTCTAGTCAAGGTG AATTATTCAATTTAATAAATTAGGGGCCTAGTGTGTTGTACCAAGGAGCTAAAAAGAGAG AACTCGCAACACCTTCCAGCCCATTCTCCACCTAACACTGGCTATACTGGCTCTCCTCTC TCTCGCTGTTTGTTCCAAAATCTAATAACCTGTCTTCCCACTAGAATTCATCATACATGT TTAAAAACCTAGTTAAATAGTAGTTAAACTGACTGCATAGATCTGGAAATGAGACAGTCT TTCTTTTACAAATCCATATAGACTATGAGTTGGGGGCAGGGGATGACACAAGAATCTATT TTCTTGCCCCCAAACCATTGCTTTCCTTCCAATGTTAAGCTTGTATTCTGTGTATTAATT CAGGTGGTTCCGTTTGGGAATGGCCTCTGTTACCCAGAGATGGGAGGGCCATCAGAACTC GGGGTTGTCTGAAAAAACACTGGTTCTAAAATTATCACTGCTTTCACTTGTTTTTAACCA TCATAGTTGTTTGATTTTGAAGGAAAAACATGAGGGTTTTTATTCTATGCTTGTTATATC TATATTGTGGTTTCGTATTTTTTAGATTTTAGTACCTGACATTTTTTTAACTTTTATTTT AGGTTCAGGGGTACATGTGCAGGTTTGTTATATAGGTAAATTTGTGTCATGGGGGTTTGT TACACAGATTATTTTATCACCCAGGGATTAAGCCTAGTACCCATTAGTTATTTTTCCTGA TCCTCTCCCTCCTCCCATCCTCCACCGTCCTATAGACCCCAGTGTGTGTTGTTCCCCTCT AAGTGTCCATGTGTTCTCATCATTTAGCTCCCACTTATAAGTAAGAACATGCGGTATTTG ATTTTCTGTTCCTGCATTAGTTTGCTAGGGATGATGGCCTCTAGCTCCATCCATGTTCTT GCAAAGTACATGATCTCATTCTCTTTTGTGGCTGCCTAGTGTTCCATGGTGTATATGTAC CACATTTTCTTTATCCAGTCTGTCATTGATGGGCATTTAGGTTGATTCCATGTCTTTGCT ATTGTAAATAGTGCTGCAGTGAAAATACGCATGCATATGTCTTTATGGTAGAATGATTTA TATTCCTTTGAGTAATGGGATTGCCGGGTCAAATGGTAGTTCTGTTTTTAGCTATCTGAG AAATTGCCACACTCTTTTCCACAATAATTGAACTAATTTACATTCCCACCAACAGTGTAA AAGCATTCCTTTTTCTCCACAACCTCACCAGCATGTGTTGGGATTTTTTTTTTTTTTTAC TTTTCAATAATAGCCATCTGACTGGTATGAGATGGTATCTCAGTGTGGTTTTGATTTTTA TTTCTTTAATGATCAGTGATGTTAAGCTCTTTTTCATATACTTGTTGGCTGCATGTATGT CTTCTTCTAAAAAGTGTCTGCTCATGTCCTTTGCCCACTTTTTAATGGGATTGTTTAATT TTTTCTTGTGAATTTACTTAAGTTCCTTATAGATGCTGGTTATTAGACCCTTCTCAGATT TGTAGCTTGCAAAAATGTTCACCCATTCTGTGGGTTGTCTTCACTCTGATGATAGTTTCT TTTGCTGTGCAGAAGATCTTCAGTTTAGTTAGATCCCATTTGTCAATTTTTGCTTTTGTT GCAATTGCTTGATGTGTTTTCATCATGAAATCTTAGCCCATTCCTATATCCAGAATGGTA TTACCTAGGTTGTCTTCCAGGGTTTTTATAGTTTGGGGTTTTACATTTAAGTCTTTAATC CATGTTGAGTTTATTTTTGTGTATGGTGTAAGGAAGGAGTCCAGTTTCAATCTTCTTCAT GGCTAGCTAGTCATCATTTATTGAGTAGGGAGTCCTTTATTCATTGCTTTTTTTTTTTTG TCAACTTTGTCAACGATCACATGGTTGTAGGTGTGCAGCCTTATTTCTGGGCTCTCTATT CTGTTTCATTGGTCTGTATGTCTGTTTCTGTACTAGTACCATGCTGTTTTGGTTACTGTA TCCCTGTAGTTTAAAGTCAGGTAGCATCATGCTTCCAGCTTTGTTCTTTTTGCTTAGGAT TGCCTTGGCAATTCAGGCTCTTTTTTGGTTCCATGTGAATTTTTAAATTGTATTTTCTAG TTCTGTGAAGAATCTCATTGGTAGTGTGATAGGAGTAACATTGAATCTATAAAATACTTT GGGCAGTATAGTCATTTTAATGATATTGATTCTTTCTATCCATGAGCATGGAATGTTTTT CCATTTGTTTGTGTCATCTCTGATTTCTTTAAGCAGTGTTTTGTGGTTCTTATTGTAGAG ATCTTTCACTTTCCTGGTTTACTGTATTTCTAGGTATTTTATTCTTTTTGTGGCAATTGT GAATTGAATTGCATTCCTGATTTGGTTCTCAGCTTGACTGTTGTTGGCATATTGGAATGC TAATTATTTTTGTACATTGATTTTGTACAACTGAGTCTTCACTGAAGTTGTTTATCAGCT TAAGGGGTTTTGGGTCAAGACTATGGGGTTTTCTAGATATAGGATCATGTCATCTGCAAA CAGAGATAGCTGTTTTCCTCTCTTCCTGTTTGGATGTCCATTATTTCTTTCTCTCACCTG ATTTATCTGGCCAGGACTTCCAATACTATGTTAAATAGGAGTGTTGAGAGAGGGAATCCT TGTCTTGTGTCAATTTTCAAGGGGAATGTTTTCAACTTTTGCCCATTCAATATGATGTTG GCTGTGGGTTTGCCATAGATGGCTAATATGTTGAGGTTTGTTCTTTAAATACCTAGTTTA TTGAGAATTTTAAACATGTTGAATTTTATTGAGAGCCTTTTCTGCATCTATTGAGATGAT CATGTGGCTTTTGTCCTTAGTTCTGTTTGTGTGGTGAATCACATTTATTGATTTGCATAT GTTGAACCAATCTTGCATCCCAGGGATGAAGCCGACTTGATTGTGGTGGCTTAAGCTTTT TGATGTGCTGCTGGATTCGATTTGCCAGTATTTTGTTGAGGATTTTTATGTCTATGTTCA TCAGAGATATTGGCCTGAAGTTTTCTTTTTTTGTTGTATCTCTGCCAAGCTTTGGTATCA GGATGACATTGGCCTCATAGAATGAGTTAAGGAAGAGTCCCTCCTTCTCAATTTTTTTGG AATAGTTTCAGTAGGAATGGTACCAGCTTTTTTTGTACATCTTGTAGAATTTGGCTATGA ATCCATCTAGTCTTAGGCTTTGTTTTGGTTGGTAGGCTATTTATTACTGATTCAATTTTG GAGCTCATTATTGGTCTGTTCAGGGATTCAGTTTCTTCCTGAGGTTTTTATTTTTATCAA ATGGAACTTAAGCTTTTTCATTTCCAATTTTTTTATGATCTAAAAATGTGCAGTTTACAG CCCTGTTCAGAATCTGCATCTTCCTCATTCTGCAGATACAGGTCCCTCAGAGCAGGTGAC TGAGTGTGTATCCTGTCTGGAGCATAATACTTATGCTAGTAGAGTTACTGTTGTCTTTAT TGTTAATTACCAAAGTTTACCACTTATCAGTCACTTACTACTTGCTGGGCATTGCACTAA GCATTTCAGTTGTATTATCTTGTTGGGTCCTTACAGCAATCCTGTGAAACAGATACTGCT ATTACCCCACTTTATAGAGAGGTAGACTGAGGCTTCCAGCATTGAAGCAAATTGCCCAAG ACTACAGAAATGTAGGTTTCTAAACATCAAGAAACAGTAACCAGTAATGATGACTAAAGC AAGGGATTGTGATTGTTCATTCATGATCCCACTGCCTTCTTTTCTTGCTTCATCCTCTCA GGGGTGACTGTTTGGGAGTTGATGACCTTTGGATCCAAGCCATATGACGGAATCCCTGCC AGCGAGATCTCCTCCATCCTGGAGAAAGGAGAACGCCTCCCTCAGCCACCCATATGTACC ATCGATGTCTACATGATCATGGTCAAGTGTGAGTGACTGGTGGGTCTGTCCACACTGCCT AGCTGAGCCTTGGTGGCTGCTCTTAGCCAAACAGCTGAGGCCTTTGCATCCCTGGAGAAA TGTCATCACATTACTTAAGGCAGGCACACAAATCCAGAAACATCTGTAAATACCCCTTCA AGCATTCTTTTAAAGACACTTCTTGACTCATTGGGCAGTATGACCTGACATTTGCCCATG TTTGCAAGCAAATAAATAAAACTAAAGTCTTCCGCAAGCCATTACACCAAAATATTCTAT TCGCTGAGTTACTCAATGAAATACCGAGTTGCCCTATATTTTGAAGCCTGTTACCAGAGA GACTGAATGTTTTTAAATGCATGGCAGTGAGTAACAACATAAGGCTAATAGAGTCAACAT TTCTGCTTTGACTTAAACCTTTTAAACCAGTGGATTTATGTGAAGTCTCTGCAGTGTGGC ATTTAAACATTTCAATCTAAATAAGAGTGTGTAATTTGATTGATGCTATTATTCTACCAG ATTCACGAGTGCAGTGGGCTCTGGAGGTAGCATTACATGCATGGGATGAGCATTTGCAAA AGAAAGTTGTATAGGGAATATGACAGAGCCAAGTTAATGTAAATATTAATGCCTTTCTGA ACTCTAGGCCACAGAGTTGATCTTTTTTAACTTCCTTGGTTTGGGCTAAGGAAGCTGTGA TCCAGAGAAGCCACGTGATTTGTCTAAGGTCACATAGCAGTCTGGCCTAAAATAGCTTGA TATGCTGTGGATGGAAAATAAATGTGATCCCTCAAGAGGCATGAGGATTTCCAGGCAGTA GCCATACCTCCAAATTGTTTAATCTGGATTTAGATTGTTGGGTAGTCACATGCAGCAGCA CAGTTAACAGTGTGTCCTCCTGTGGAAGTTGCCAGCACAGCCAGCCCTCTCACTTGCATG CATGCCCACCAGCCTTCTCACTTGCATGCATGCCCACTGGGTATGTGCTGTACTGGAGAC GCCGGGGGTAGGGGCCCAGTCCCAACCCCAAATTCTTTAAAGCCTATTTTTCTAAGTTGC ATCTGGTTTCCTACCTGAAGGAATGCTAAGGGTGGATGTTGAGTGAGGACCTTGGTGCAG GGCACCCTGCAGTCAGGATAGTTCATGGAGAGCAATTGTACAGACCCACACTGCTCCATC CCCTCAGGCGTAACACAGGATGCTGACCCCAGGAAGAGTGGGCGTAGAAAAACTAGAGGG CATTATTGTTATTCTGATTCAAATGTACAGTGCTGGCATGGTCTTTAAACAGTAACCAGT ACTAGCTGGCCAAGACAGAAAAGTCTACCACAAAGACTTGGTTCTTTCATCACTTATTTG ACTGGAAGTGTCGCATCACCAATGCCTTCTTTAAGCAATGCCATCTTTATCATTTCTTCC AGTGTTCTAATTGCACTGTTTTTTCTCATTCCTTCCCCAGGCTGGATGATAGACGCAGAT AGTCGCCCAAAGTTCCGTGAGTTGATCATCGAATTCTCCAAAATGGCCCGAGACCCCCAG CGCTACCTTGTCATTCAGGTACAAATTGCAGTCTGTGCTTCCATTGGGAAGAGTCCCTCT AATGAGCATCTCATGTCACTGTGTTCTGTCACATGCCAGCCTGGCCTCCCTGTGTCCCAG ATCGCATTATTAAACCCTCCAGCGCATTAGAGCAAGCCTCAGTAAGGCGCAGGCCACATC GTGAACTAAGCAGCATCCGTGAGTGGGGCCCACCCAACTCCATCTCCCCCTCCCCGTCTG AACTCTCCTCTGGTGCTCGTCCTCACTGTCCGGCTAGCCAAAGCCTCAGCTGGGTCTAAG AGAGAAGCATGGTCTATTGGGCTTTGGTGTCAGGCAGACGTGGCTTCACACCCCTGACTC TCCACTTCTTCGCATCACCCAGGCAGCCGATCCACCTATCTCCTTCCATAACACAGGAAT ACCAAAACCAAGCTCACAGGATTGTCTCAAAGATTCAATAAAATATGTTGCAAAATACGC TCCCTAACACCTCACAGCAAGGTGCACACTCGATGAATGCTGCAGCTTCTTCCCTTTCTG TTTCCTCAGAAGCTATTTGAATCTCATGTAGGGGCTTTCAAGCATCAAAGGATGGTTCAT GTTTTATTTTAAGGCACCCACATCATGTCATGAGGGGAGGCAGCTATAATTTAGAGAACC AAGGGGGATTTCATTATAACAAAATTGGCAAACACACAGGCACCTGCTGGCAATAGACCC CTGCTCCTATAGCCAAGAAGTGGAATAGCATCTCTACGGGCCATTCTAATAGCCTCAAAA TCTCTGCACCAGGGGGATGAAAGAATGCATTTGCCAAGTCCTACAGACTCCAACTTCTAC CGTGCCCTGATGGATGAAGAAGACATGGACGACGTGGTGGATGCCGACGAGTACCTCATC CCACAGCAGGGCTTCTTCAGCAGCCCCTCCACGTCACGGACTCCCCTCCTGAGCTCTCTG GTATGAAATCTCTGTCTCTCTCTCTCTCTCAAGCTGTGTCTACTCATTTGAACAAATTGA ATTTTAGGGAAAATAACCATCTAGTGAAACTCACATGGATATGAAGTCAATTTTAACCAA ATGGTAAAATCAAAATCAAAATAAATTAAGTGTATTAATTATTTTGTTGCATTGCAACAA CTTGATTGTAAGCCTTTTAGGTCCACTATGGAATGTAATTAAATCAAAACTAAACCTAGT TGCTCTAAAACTAACGATTAAGACAAAAATTAAACACCTTCACAATATACCCTCCATGAG GCACACCACCTGCATTCAGGAAAAGTGGATGAGATGTGGTACAAGCATTCCATGGGCAAC TTCTCTGTTTCTTTTTCAGAGTGCAACCAGCAACAATTCCACCGTGGCTTGCATTGATAG AAATGGGGTATGTATGAACACCTTATAAGCCAGAATTTACAGCTCTCCACTATGGCTCTA TTTTACATGGAAAATGCCTTAACCTAAATAATTTTAACCCAGATAATCTTGAGTTTTCTT CCTGTGTGGGTTTTTCCCTGCACGGCTGTCACGCCTCACAGTGCCGTTCAAAGCGTGACT CCTGGACCAGTAGTAGCATCGCCTGGCCTTGTTAGAAACGCCATTTTTCAGGCCACTGCC CCAGTTTGACCAAATCAGGACCTCTGGGGGTGGCACCCAGTAGTCTATGTTTGAGCCACT TTCCAGGTGATGCTGATGTCTGTTGAAGTGTGAGGCCGTGGTCTAGACCGCACTGTGCCA TGCAGAAACCACTAGCCACATGTGGCTACTTCAACTTAAATGTTAATGAGTTAAAATGAA ATAAAATATAAAATTCAGTTTCTCACACATGTGAAGTGTCCAGTAGCCACACGTGGCTAG TGGTGACCGTATTGAAGAGCACCGCTCATAGCACACCTCCCTCACTGCGGAAAGTTCTGC TGTACAGCACCCAGCACAGCCCTGCTGCCCACCCTGCAGCCTGTGGCCCAGTAGCACCAG CACCCACCAGGGTGCAGACTCTCAGGCCTGCCCAACCTACTAATCAGAACCAGCATCTCA AGGAGATCTCGGGTGATTTTTGCAAACACTGAAGTTGGGGCAGCCCTGACCGGAGTAACC TTCCCTCATTTCCTCCTGCAGCTGCAAAGCTGTCCCATCAAGGAAGACAGCTTCTTGCAG CGATACAGCTCAGACCCCACAGGCGCCTTGACTGAGGACAGCATAGACGACACCTTCCTC CCAGTGCCTGGTGAGTGGCTTGTCTGGAAACAGTCCTGCTCCTCAACCTCCTCGACCCAC TCAGCAGCAGCCAGTCTCCAGTGTCCAAGCCAGGTGCTCCCTCCAGCATCTCCAGAGGGG GAAACAGTGGCAGATTTGCAGACACAGTGAAGGGCGTAAGGAGCAGATAAACACATGACC GAGCCTGCACAAGCTCTTTGTTGTGTCTGGTTGTTTGCTGTACCTCTGTTGTAAGAATGA ATCTGCAAAATTTCTAGCTTATGAAGCAAATCACGGACATACACATCTGTGTGTGTGAGT GTTCATGATGTGTGTACATCTGTGTATGTGTGTGTGTGTATGTGTGTGTTTGTGACAGAT TTGATCCCTGTTCTCTCTGCTGGCTCTATCTTGACCTGTGAAACGTATATTTAACTAATT AAATATTAGTTAATATTAATAAATTTTAAGCTTTATCCAGA bcftools-1.21/test/norm.right-align.gff000066400000000000000000000016231467060157400201060ustar00rootroot000000000000007 ensembl_havana gene 100 29201 . + . ID=gene:ENSG00000146648;Name=EGFR;biotype=protein_coding;description=epidermal growth factor receptor [Source:HGNC Symbol%3BAcc:3236];gene_id=ENSG00000146648;logic_name=ensembl_havana_gene;version=11 7 ensembl_havana mRNA 100 29201 . + . ID=transcript:ENST00000455089;Parent=gene:ENSG00000146648;Name=EGFR-004;biotype=protein_coding;havana_transcript=OTTHUMT00000343056;havana_version=1;tag=basic;transcript_id=ENST00000455089;version=1 7 havana gene 5875 15059 . - . ID=gene:ENSG00000224057;Name=EGFR-AS1;biotype=antisense;description=EGFR antisense RNA 1 [Source:HGNC Symbol%3BAcc:40207];gene_id=ENSG00000224057;logic_name=havana;version=1 7 havana transcript 5875 15059 . - . ID=transcript:ENST00000442411;Parent=gene:ENSG00000224057;Name=EGFR-AS1-001;biotype=antisense;havana_transcript=OTTHUMT00000343091;havana_version=1;tag=basic;transcript_id=ENST00000442411;version=1 bcftools-1.21/test/norm.right-align.vcf000066400000000000000000000005371467060157400201250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 7 897 . GGAATTAAGA G . . . 7 910 . G C . . . bcftools-1.21/test/norm.rmdup.1.out000066400000000000000000000005721467060157400172360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789242 . C G . . . 1 789243 . C CA . . . 1 789243 . C CCA . . . 1 789244 . C A . . . 1 789244 . C CA . . . 1 789244 . C CCA . . . 1 789245 . C T,CA,TTT . . . bcftools-1.21/test/norm.rmdup.2.1.out000066400000000000000000000020041467060157400173660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00096 HG00097 HG00099 HG00100 HG00101 HG00102 HG00103 HG00105 HG00106 HG00107 22 16854058 . C G . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16854058 . C T . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16897908 . C A . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16897908 . C T . . AC=2;AN=20 GT 0|0 0|1 0|0 0|0 0|0 0|0 0|0 0|0 1|0 0|0 22 16930571 . A C . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16930571 . A G . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 bcftools-1.21/test/norm.rmdup.2.2.out000066400000000000000000000014401467060157400173720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00096 HG00097 HG00099 HG00100 HG00101 HG00102 HG00103 HG00105 HG00106 HG00107 22 16854058 . C G . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16897908 . C A . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16930571 . A C . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 bcftools-1.21/test/norm.rmdup.2.out000066400000000000000000000007161467060157400172370ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789242 . C G . . . 1 789242 . C A . . . 1 789243 . C CA . . . 1 789244 . C A . . . 1 789244 . C CA . . . 1 789244 . C T . . . 1 789245 . C T,CA,TTT . . . 1 789245 . C T,A . . . 1 789245 . C T . . . 1 789245 . C A,T . . . 1 789245 . C T . . . bcftools-1.21/test/norm.rmdup.2.vcf000066400000000000000000000020041467060157400171760ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00096 HG00097 HG00099 HG00100 HG00101 HG00102 HG00103 HG00105 HG00106 HG00107 22 16854058 . C G . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16854058 . C T . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16897908 . C A . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16897908 . C T . . AC=2;AN=20 GT 0|0 0|1 0|0 0|0 0|0 0|0 0|0 0|0 1|0 0|0 22 16930571 . A C . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 22 16930571 . A G . . AC=0;AN=20 GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 bcftools-1.21/test/norm.rmdup.3.1.out000066400000000000000000000005231467060157400173730ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . A . . SVLEN=-1000 1 1 . A . . SVLEN=-2000 1 1 . A . . SVLEN=-3000 1 18 . AC A . . . bcftools-1.21/test/norm.rmdup.3.2.out000066400000000000000000000004271467060157400173770ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . A . . SVLEN=-1000 1 18 . AC A . . . bcftools-1.21/test/norm.rmdup.3.fa000066400000000000000000000000351467060157400170110ustar00rootroot00000000000000>1 ACGTACGTCCCGTACGTACCCCCGT bcftools-1.21/test/norm.rmdup.3.out000066400000000000000000000005141467060157400172340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789242 . C G . . . 1 789243 . C CA . . . 1 789244 . C A . . . 1 789244 . C CA . . . 1 789245 . C T,CA,TTT . . . bcftools-1.21/test/norm.rmdup.3.vcf000066400000000000000000000007601467060157400172060ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10 . C . . SVLEN=-1000 1 10 . C . . SVLEN=-1000 1 10 . C . . SVLEN=-2000 1 10 . C . . SVLEN=-1000 1 10 . C . . SVLEN=-3000 1 10 . C . . SVLEN=-2000 1 10 . C . . SVLEN=-1000 1 10 . C . . SVLEN=-3000 1 10 . C . . SVLEN=-2000 1 20 . CCC CC . . . 1 20 . CC C . . . bcftools-1.21/test/norm.rmdup.4.out000066400000000000000000000004661467060157400172430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789242 . C G . . . 1 789243 . C CA . . . 1 789244 . C A . . . 1 789245 . C T,CA,TTT . . . bcftools-1.21/test/norm.rmdup.5.out000066400000000000000000000007201467060157400172350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789242 . C G . . . 1 789242 . C A . . . 1 789243 . C CA . . . 1 789243 . C CCA . . . 1 789244 . C A . . . 1 789244 . C CA . . . 1 789244 . C T . . . 1 789244 . C CCA . . . 1 789245 . C T,CA,TTT . . . 1 789245 . C T,A . . . 1 789245 . C T . . . bcftools-1.21/test/norm.rmdup.vcf000066400000000000000000000007441467060157400170470ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789242 . C G . . . 1 789242 . C A . . . 1 789243 . C CA . . . 1 789243 . C CCA . . . 1 789244 . C A . . . 1 789244 . C CA . . . 1 789244 . C T . . . 1 789244 . C CCA . . . 1 789245 . C T,CA,TTT . . . 1 789245 . C T,A . . . 1 789245 . C T . . . 1 789245 . C A,T . . . 1 789245 . C T . . . 1 789245 . C CA,TTT,T . . . bcftools-1.21/test/norm.setref.out000066400000000000000000000056171467060157400172450ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAACCCTAAA,TAA 999 PASS INDEL;AN=4;AC=0,2;DP=19 GT 0/2 0/2 2 101 . A c 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 105 . T 999 PASS END=112;AN=4;AC=3 GT:DP 0/1:1 1/1:1 2 115 . c t 999 PASS INDEL;AN=4;AC=0 GT:DP 0/0:1 0/0:1 20 3 . g c 999 PASS INDEL;AN=4;AC=3 GT 1/1 1/0 20 3 . gatg gact 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 10 . C . 999 PASS INDEL;AN=4;AC=1 GT 1/0 0/0 20 275 . a c,g,t,aaa 999 PASS INDEL;AN=2;AC=0,0,0,0 GT 0 0 bcftools-1.21/test/norm.setref.vcf000066400000000000000000000056171467060157400172140ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAACCCTAAA TAAACCCTAAA,TAA 999 PASS INDEL;AN=4;AC=2,2;DP=19 GT 1/2 1/2 2 101 . . c 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 105 . n 999 PASS END=112;AN=4;AC=3 GT:DP 0/1:1 1/1:1 2 115 . t c 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . c g 999 PASS INDEL;AN=4;AC=1 GT 0/0 0/1 20 3 . gact gatg 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 10 . . . 999 PASS INDEL;AN=4;AC=1 GT 1/0 0/0 20 275 . g c,a,t,aaa 999 PASS INDEL;AN=2;AC=0,2,0,0 GT 2 2 bcftools-1.21/test/norm.sort.1.out000066400000000000000000000003251467060157400170720ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr19 50359054 . C G . . . chr19 50359054 . C T . . . chr19 50359054 . C A . . . bcftools-1.21/test/norm.sort.2.out000066400000000000000000000003251467060157400170730ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr19 50359054 . C A . . . chr19 50359054 . C G . . . chr19 50359054 . C T . . . bcftools-1.21/test/norm.sort.vcf000066400000000000000000000001571467060157400167050ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr19 50359054 . C G,T,A . . . bcftools-1.21/test/norm.split.2.out000066400000000000000000000056621467060157400172500ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.2-216-gdffc67f-dirty+htslib-1.2.1-216-gd2ed7e6-dirty ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G 41.4503 . . 1 789262 . G A 36.0809 . . 1 789280 . T C 40.0265 . . 1 789334 . A T 67 . . 1 789348 . T A 44.5622 . . 1 789368 . A T 18.5381 . . 1 789369 . C T 30.0396 . . 1 789396 . A C 35.7056 . . 1 789402 . G T 35.0554 . . 1 789403 . T A 35.0681 . . 1 789417 . T G 35.0681 . . 1 789420 . T A 35.0681 . . 1 789429 . A C 39.1119 . . 1 789435 . C T 35.1179 . . 1 789481 . G A 94 . . 1 789489 . C A 89 . . 1 789491 . C G 100 . . 1 789568 . TATGGAATGGAATGGAATGGAATG TATGGAATGGAATGGAATG 295 . . 1 789631 . G A 3.18972 . . 1 789642 . T G 3.66362 . . 1 789660 . C T 35.0294 . . 1 789666 . T G 16.1313 . . 1 789673 . A T 52 . . 1 789675 . T G 20.7408 . . 1 789676 . C T 26.6621 . . 1 789680 . A T 21.5713 . . 1 789680 . AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG 23.495 . . 1 789685 . T G 6.53871 . . 1 789690 . T G 16.2287 . . 1 789690 . T C 16.2287 . . 1 789691 . G T 21.8633 . . 1 789691 . G C 21.8633 . . 1 789692 . G A 31.8203 . . 1 789695 . T A 7.03922 . . 1 789696 . G A 64 . . 1 789696 . G T 64 . . 1 789696 . G C 64 . . 1 789697 . G A 116 . . 1 789700 . T A 27.3447 . . 1 789700 . T G 27.3447 . . 1 789704 . A C 12.9378 . . 1 789704 . A T 12.9378 . . 1 789704 . A G 12.9378 . . 1 789706 . G C 4.49441 . . 1 789706 . G A 4.49441 . . 1 789707 . G C 6.28796 . . 1 789707 . G A 6.28796 . . 1 789710 . T G 59 . . 1 789710 . T A 59 . . 1 789711 . G T 15.1544 . . 1 789713 . A C 6.69714 . . 1 789717 . G A 82 . . 1 789720 . T G 26.241 . . 1 789721 . G A 99 . . 1 789721 . G T 99 . . 1 789727 . G A 5.18898 . . 1 789727 . G C 5.18898 . . 1 789730 . T A 73 . . 1 789730 . T C 73 . . 1 789731 . G T 111 . . 1 789732 . G T 24.8095 . . 1 789735 . T G 61 . . 1 789737 . G T 69 . . 1 789737 . G A 69 . . 1 789739 . A T 48.5355 . . 1 789740 . T A 29.8166 . . 1 789747 . A G 187 . . 1 789747 . A C 187 . . 1 789747 . A T 187 . . 1 789749 . C G 19.1565 . . 1 789750 . T A 12.5086 . . 1 789750 . T C 12.5086 . . 1 789752 . C G 284 . . 1 789757 . G A 7.13117 . . 1 789765 . T A 191 . . 1 789767 . G A 16.2222 . . 1 789769 . C T 17.4827 . . 1 789770 . T G 64 . . 1 789770 . T A 64 . . 1 789772 . G A 31.6793 . . 1 789772 . G C 31.6793 . . 1 789775 . T A 125 . . 1 789775 . T G 125 . . 1 789776 . A G 151 . . 1 789777 . G C 22.9639 . . 1 789781 . G A 89 . . 1 789795 . A T 11.555 . . 1 789816 . G A 29.3537 . . 1 789957 . C G 19.4796 . . 1 790009 . C T 55 . . 1 790136 . A G 85 . . 1 790156 . G A 19.4198 . . 1 790176 . A G 86 . . 1 790179 . C T 4.20807 . . 1 790181 . C T 12.5149 . . 1 790186 . G A 86 . . 1 790189 . T A 76 . . 1 790202 . G A 86 . . 1 790202 . G C 86 . . 1 790206 . C A 18.4041 . . 1 790206 . C T 18.4041 . . bcftools-1.21/test/norm.split.2.vcf000066400000000000000000000047001467060157400172070ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##samtoolsVersion=1.2-216-gdffc67f-dirty+htslib-1.2.1-216-gd2ed7e6-dirty ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G 41.4503 . . 1 789262 . G A 36.0809 . . 1 789280 . T C 40.0265 . . 1 789334 . A T 67 . . 1 789348 . T A 44.5622 . . 1 789368 . A T 18.5381 . . 1 789369 . C T 30.0396 . . 1 789396 . A C 35.7056 . . 1 789402 . G T 35.0554 . . 1 789403 . T A 35.0681 . . 1 789417 . T G 35.0681 . . 1 789420 . T A 35.0681 . . 1 789429 . A C 39.1119 . . 1 789435 . C T 35.1179 . . 1 789481 . G A 94 . . 1 789489 . C A 89 . . 1 789491 . C G 100 . . 1 789568 . TATGGAATGGAATGGAATGGAATG TATGGAATGGAATGGAATG 295 . . 1 789631 . G A 3.18972 . . 1 789642 . T G 3.66362 . . 1 789660 . C T 35.0294 . . 1 789666 . T G 16.1313 . . 1 789673 . A T 52 . . 1 789675 . T G 20.7408 . . 1 789676 . C T 26.6621 . . 1 789680 . A T 21.5713 . . 1 789680 . AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG 23.495 . . 1 789685 . T G 6.53871 . . 1 789690 . T G,C 16.2287 . . 1 789691 . G T,C 21.8633 . . 1 789692 . G A 31.8203 . . 1 789695 . T A 7.03922 . . 1 789696 . G A,T,C 64 . . 1 789697 . G A 116 . . 1 789700 . T A,G 27.3447 . . 1 789704 . A C,T,G 12.9378 . . 1 789706 . G C,A 4.49441 . . 1 789707 . G C,A 6.28796 . . 1 789710 . T G,A 59 . . 1 789711 . G T 15.1544 . . 1 789713 . A C 6.69714 . . 1 789717 . G A 82 . . 1 789720 . T G 26.241 . . 1 789721 . G A,T 99 . . 1 789727 . G A,C 5.18898 . . 1 789730 . T A,C 73 . . 1 789731 . G T 111 . . 1 789732 . G T 24.8095 . . 1 789735 . T G 61 . . 1 789737 . G T,A 69 . . 1 789739 . A T 48.5355 . . 1 789740 . T A 29.8166 . . 1 789747 . A G,C,T 187 . . 1 789749 . C G 19.1565 . . 1 789750 . T A,C 12.5086 . . 1 789752 . C G 284 . . 1 789757 . G A 7.13117 . . 1 789765 . T A 191 . . 1 789767 . G A 16.2222 . . 1 789769 . C T 17.4827 . . 1 789770 . T G,A 64 . . 1 789772 . G A,C 31.6793 . . 1 789775 . T A,G 125 . . 1 789776 . A G 151 . . 1 789777 . G C 22.9639 . . 1 789781 . G A 89 . . 1 789795 . A T 11.555 . . 1 789816 . G A 29.3537 . . 1 789957 . C G 19.4796 . . 1 790009 . C T 55 . . 1 790136 . A G 85 . . 1 790156 . G A 19.4198 . . 1 790176 . A G 86 . . 1 790179 . C T 4.20807 . . 1 790181 . C T 12.5149 . . 1 790186 . G A 86 . . 1 790189 . T A 76 . . 1 790202 . G A,C 86 . . 1 790206 . C A,T 18.4041 . . bcftools-1.21/test/norm.split.3.out000066400000000000000000000052231467060157400172420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA 999 PASS INDEL;AN=4;DP=19;ISTR=SomeString;XRS=AAA,BBB;XAS=AAA;XGS=A,B,C GT:DP:FRS:FAS:FGF 1/0:1:AAAA,BBB:A:1e+06,2e+06,3e+06 1/0:1:AAAA,BBB:A:1e+06,2e+06,3e+06 1 105 . TAAACCCTAAA TAACCCTAAA 999 PASS INDEL;AN=4;DP=19;ISTR=SomeString;XRS=AAA,DDD;XAS=DDD;XGS=A,E,F GT:DP:FRS:FAS:FGF 0/1:1:AAAA,CC:BB:1e+06,500000,9e+09 0/1:1:AAAA,CC:BB:1e+06,500000,9e+09 bcftools-1.21/test/norm.split.3.vcf000066400000000000000000000057251467060157400172200ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2,7;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000,7;XRI=1111,2222,5555,7;XRS=AAA,BBB,DDD,xx;XAF=1e+06,500000,7;XAI=1111,5555,7;XAS=AAA,DDD,xx;XGF=1e+06,2e+06,3e+06,500000,.,9e+09,7;XGI=1111,2222,3333,5555,.,9999,7;XGS=A,B,C,E,.,F,x GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6,7:1:1e+06,2e+06,500000,7:1111,2222,5555,7:AAAA,BBB,CC:1e+06,500000,7:1111,5555,7:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999,7:A,BB,CCC,EEEE,.,FFFFF,XX bcftools-1.21/test/norm.split.4.1.out000066400000000000000000000016321467060157400174020ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 20 10101010 . C G . PASS AD=2,48;XX=2,48 GT:AD:XX 1/0:2,48:2,48 20 10101010 . C T . PASS AD=2,.;XX=2,. GT:AD:XX 0/1:2,.:2,. 20 20202020 . C G . PASS AD=2,48;XX=2,48 GT:AD:XX 1/0:2,48:2,48 20 20202020 . C T . PASS AD=2,61;XX=2,61 GT:AD:XX 0/1:2,61:2,61 bcftools-1.21/test/norm.split.4.2.out000066400000000000000000000016401467060157400174020ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 20 10101010 . C G . PASS AD=2,48;XX=2,48 GT:AD:XX 1/0:2,48:2,48 20 10101010 . C T . PASS AD=50,.;XX=2,. GT:AD:XX 0/1:50,.:2,. 20 20202020 . C G . PASS AD=63,48;XX=2,48 GT:AD:XX 1/0:63,48:2,48 20 20202020 . C T . PASS AD=50,61;XX=2,61 GT:AD:XX 0/1:50,61:2,61 bcftools-1.21/test/norm.split.4.vcf000066400000000000000000000014021467060157400172050ustar00rootroot00000000000000##fileformat=VCFv4.3 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 20 10101010 . C G,T . PASS AD=2,48,.;XX=2,48,. GT:AD:XX 1/2:2,48,.:2,48,. 20 20202020 . C G,T . PASS AD=2,48,61;XX=2,48,61 GT:AD:XX 1/2:2,48,61:2,48,61 bcftools-1.21/test/norm.split.5.1.out000066400000000000000000000005361467060157400174050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 11 . A C . . . GT 1|0 0|1 1 11 . A T . . . GT .|0 0|. 1 22 . A C . . . GT .|0 0|. 1 22 . A T . . . GT 1|0 0|1 bcftools-1.21/test/norm.split.5.vcf000066400000000000000000000003661467060157400172160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 11 . A C,T . . . GT 1|0 0|1 1 22 . A C,T . . . GT 2|0 0|2 bcftools-1.21/test/norm.split.and.norm.out000066400000000000000000000124151467060157400206150ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTA T 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06;XRI=1111,2222;XRS=AAA,BBB;XAF=1e+06;XAI=1111;XAS=AAA;XGF=1e+06,2e+06,3e+06;XGI=1111,2222,3333;XGS=A,B,C GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1 105 . TA T 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,500000;XRI=1111,5555;XRS=AAA,DDD;XAF=500000;XAI=5555;XAS=DDD;XGF=1e+06,500000,9e+09;XGI=1111,5555,9999;XGS=A,E,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 101 . A ATT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 101 . A AT 999 PASS INDEL;AN=4;AC=2 GT:DP 0/1:1 0/1:1 2 114 . T TTC 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 5 . TG CT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGG T . PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:1,4,6:1 0/1:1,4,6:1 20 5 . T TG . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,7,10:1 0/0:1,7,10:1 20 5 . TGGG AC . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,11,15:1 0/0:1,11,15:1 20 6 . GGG AC . PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:1,2,3:1 1/0:1,2,3:1 20 59 . A . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 84 . G T 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . T A 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . C CAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:0,3,5:1 1/0:0,3,5:1 20 273 . C CAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:0,3,5:1 0/1:0,3,5:1 20 273 . C CAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 273 . C CAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C 999 PASS INDEL;AN=2;AC=0 GT:PL:DP:FGF:FGI:FGS:FSTR 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 20 275 . A G 999 PASS INDEL;AN=2;AC=2 GT:PL:DP:FGF:FGI:FGS:FSTR 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 20 300 . T C 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . T G 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 21 1 id T TTTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 21 1 id T TTTATTATTATTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 21 1 id TTTA T 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 21 1 id T TTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/norm.split.merge.1.out000066400000000000000000000016761467060157400203460ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO chr1 29291 . C T,G,A . . . chr2 29292 . T C . . . chr2 29292 . T TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T CGTA . . . bcftools-1.21/test/norm.split.merge.2.out000066400000000000000000000017501467060157400203400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO chr1 29291 . C T . . . chr1 29291 . C G . . . chr1 29291 . C A . . . chr2 29292 . T C . . . chr2 29292 . T TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T CGTA . . . bcftools-1.21/test/norm.split.merge.3.out000066400000000000000000000026141467060157400203410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO chr1 29291 . C T,G,A . . . chr2 29292 . T C . . . chr2 29292 . T TCCCTCTCCTTTCTCCTCTCTAGCC . . . chr2 29292 . T TCTCTTTCTCACTGTCTCTCTAGCC . . . chr2 29292 . T TCCCTCTCCTTTCTCCTCTCTAGC . . . chr2 29292 . T TCCATCTGTATCCTCTCTAAGC . . . chr2 29292 . T TCCCTCTCCTTTCTCCTCAGCC . . . chr2 29292 . T TCCCTCTCCCTTTCTCCTCTCTAGCC . . . chr2 29292 . T TCCTCTCCTTTCTCCTCTACCGC . . . chr2 29292 . T TCCCTCTCCTTTCTCTCTCTAGCC . . . chr2 29292 . T TCCCTCTCCTTTCTCCTCTAGCC . . . chr2 29292 . T TCCCTCTCCTTTTCCTCCCCAGCC . . . chr2 29292 . T TCCCTCTCCTTCTCCTCTCTAGCC . . . chr2 29292 . T TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T TCCCTCTCCTTTCTCCTCTCTAGCC . . . chr3 29292 . T TCTCTTTCTCACTGTCTCTCTAGCC . . . chr3 29292 . T TCCCTCTCCTTTCTCCTCTCTAGC . . . chr3 29292 . T TCCATCTGTATCCTCTCTAAGC . . . chr3 29292 . T TCCCTCTCCTTTCTCCTCAGCC . . . chr3 29292 . T TCCCTCTCCCTTTCTCCTCTCTAGCC . . . chr3 29292 . T TCCTCTCCTTTCTCCTCTACCGC . . . chr3 29292 . T TCCCTCTCCTTTCTCTCTCTAGCC . . . chr3 29292 . T TCCCTCTCCTTTCTCCTCTAGCC . . . chr3 29292 . T TCCCTCTCCTTTTCCTCCCCAGCC . . . chr3 29292 . T TCCCTCTCCTTCTCCTCTCTAGCC . . . chr3 29292 . T TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T CGTA . . . bcftools-1.21/test/norm.split.merge.4.out000066400000000000000000000016241467060157400203420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO chr1 29291 . C T,G,A . . . chr2 29292 . T C,TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T CGTA,TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . bcftools-1.21/test/norm.split.merge.5.out000066400000000000000000000016761467060157400203520ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO chr1 29291 . C T . . . chr1 29291 . C G . . . chr1 29291 . C A . . . chr2 29292 . T C,TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T CGTA,TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . bcftools-1.21/test/norm.split.merge.vcf000066400000000000000000000015401467060157400201440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##contig= ##reference=file:ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO chr1 29291 . C T,G,A . . . chr2 29292 . T C,TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . chr3 29292 . T CGTA,TCCCTCTCCTTTCTCCTCTCTAGCC,TCTCTTTCTCACTGTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTCTAGC,TCCATCTGTATCCTCTCTAAGC,TCCCTCTCCTTTCTCCTCAGCC,TCCCTCTCCCTTTCTCCTCTCTAGCC,TCCTCTCCTTTCTCCTCTACCGC,TCCCTCTCCTTTCTCTCTCTAGCC,TCCCTCTCCTTTCTCCTCTAGCC,TCCCTCTCCTTTTCCTCCCCAGCC,TCCCTCTCCTTCTCCTCTCTAGCC,TCCCTCTCCCTTCTCCTCTCTCAC . . . bcftools-1.21/test/norm.split.out000066400000000000000000000127721467060157400171100ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06;XRI=1111,2222;XRS=AAA,BBB;XAF=1e+06;XAI=1111;XAS=AAA;XGF=1e+06,2e+06,3e+06;XGI=1111,2222,3333;XGS=A,B,C GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1 105 . TAAACCCTAAA TAACCCTAAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,500000;XRI=1111,5555;XRS=AAA,DDD;XAF=500000;XAI=5555;XAS=DDD;XGF=1e+06,500000,9e+09;XGI=1111,5555,9999;XGS=A,E,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 114 . TC TTC 999 PASS INDEL;AN=4;AC=2 GT:DP 0/1:1 0/1:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC . PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:1,2,3:1 1/0:1,2,3:1 20 5 . TGGG TG . PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:1,4,6:1 0/1:1,4,6:1 20 5 . TGGG TGGGG . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,7,10:1 0/0:1,7,10:1 20 5 . TGGG AC . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,11,15:1 0/0:1,11,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:0,3,5:1 1/0:0,3,5:1 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:0,3,5:1 0/1:0,3,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C 999 PASS INDEL;AN=2;AC=0 GT:PL:DP:FGF:FGI:FGS:FSTR 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 20 275 . A G 999 PASS INDEL;AN=2;AC=2 GT:PL:DP:FGF:FGI:FGS:FSTR 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . T C 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . T G 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 21 1 id TTTA TTTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 21 1 id TTTA TTTATTATTATTATTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 21 1 id TTTA T 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 21 1 id TTTA TTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/norm.split.vcf000066400000000000000000000113031467060157400170440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C,G 999 PASS INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 300 . T C,G 999 PASS INDEL;AN=0;AC=0,0 GT:PL:DP ./.:0,0,0,0,0,0:0 ./.:0,0,0,0,0,0:0 21 1 id TTTA TTTATTATTA,TTTATTATTATTATTATTATTA,T,TTATTATTA 999 PASS INDEL;AN=0;AC=0,0,0,0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/norm.string-tags.1.out000066400000000000000000000024021467060157400203430ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 12 111 . CC GG . . . FRS a,b aa,bb aaa,bbb . 12 111 . CC GT . . . FRS a,c aa,cc aaa,ccc . 12 222 . CC GG . . . FAS b bb bbb . 12 222 . CC GT . . . FAS c cc ccc . 12 333 . CC GG . . . FGS 1,2 11,22 111,222 . 12 333 . CC GT . . . FGS 1,3 11,33 111,333 . 12 444 . CC GG . . . FGS 11,12,22 1111,1122,2222 111111,111222,222222 . 12 444 . CC GT . . . FGS 11,13,33 1111,1133,3333 111111,111333,333333 . 12 555 . CC GG . . XRS=aaa,bb . . . . . 12 555 . CC GT . . XRS=aaa,c . . . . . 12 666 . CC GG . . XRS=. . . . . . 12 666 . CC GT . . XRS=. . . . . . 12 777 . CC GG . . XAS=bbb . . . . . 12 777 . CC GT . . XAS=cc . . . . . 12 888 . CC GG . . XAS=bbb . . . . . 12 888 . CC GT . . XAS=. . . . . . bcftools-1.21/test/norm.string-tags.vcf000066400000000000000000000020221467060157400201510ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##FILTER= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3 S4 12 111 . CC GG,GT . . . FRS a,b,c aa,bb,cc aaa,bbb,ccc . 12 222 . CC GG,GT . . . FAS b,c bb,cc bbb,ccc . 12 333 . CC GG,GT . . . FGS 1,2,3 11,22,33 111,222,333 . 12 444 . CC GG,GT . . . FGS 11,12,22,13,23,33 1111,1122,2222,1133,2233,3333 111111,111222,222222,111333,222333,333333 . 12 555 . CC GG,GT . . XRS=aaa,bb,c . . . . . 12 666 . CC GG,GT . . XRS=aaa . . . . . 12 777 . CC GG,GT . . XAS=bbb,cc . . . . . 12 888 . CC GG,GT . . XAS=bbb . . . . . bcftools-1.21/test/norm.symbolic.1.out000066400000000000000000000011051467060157400177210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 20 15 . TAC T . . ORI=20|24|ACA|A 20 15 . T . . END=17;SVTYPE=DEL;ORI=20|24|A| 20 93 . CAAA C . . ORI=20|98|AAAA|A 20 93 . C . . END=96;SVTYPE=DEL;ORI=20|98|A| bcftools-1.21/test/norm.symbolic.2.out000066400000000000000000000010531467060157400177240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 20 15 . TAC T, . . END=17;SVTYPE=DEL;ORI=20|24|ACA|A, 20 93 . CAAA C . . ORI=20|98|AAAA|A 20 93 . C . . END=96;SVTYPE=DEL;ORI=20|98|A| bcftools-1.21/test/norm.symbolic.2.vcf000066400000000000000000000005271467060157400177000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 20 24 . ACA A, . . END=26;SVTYPE=DEL 20 98 . AAAA A . . . 20 98 . A . . END=101;SVTYPE=DEL bcftools-1.21/test/norm.symbolic.3.1.out000066400000000000000000000006151467060157400200670ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 11 . G GGATTACA . PASS SVTYPE=DUP;SVLEN=7 1 11 . G . PASS SVTYPE=DUP;SVLEN=7 bcftools-1.21/test/norm.symbolic.3.fa000066400000000000000000000000601467060157400175010ustar00rootroot00000000000000>1 ACTCACAAAGGGATTACAGATTACAGATTACAGGGGATCCAGAT bcftools-1.21/test/norm.symbolic.3.vcf000066400000000000000000000005311467060157400176740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 26 . G GATTACAG . PASS SVTYPE=DUP;SVLEN=7 1 26 . G . PASS SVTYPE=DUP;SVLEN=7 bcftools-1.21/test/norm.symbolic.fa000066400000000000000000000001761467060157400173500ustar00rootroot00000000000000>20 AGGATGGGGCTCATTACACACACACACCTTGTCTCCAGAATCACTGGTGAGGAAGGGGAG TGCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAGGCCAT bcftools-1.21/test/norm.symbolic.vcf000066400000000000000000000005471467060157400175420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 20 24 . ACA A . . . 20 24 . A . . END=26;SVTYPE=DEL 20 98 . AAAA A . . . 20 98 . A . . END=101;SVTYPE=DEL bcftools-1.21/test/norm.telomere.out000066400000000000000000000002351467060157400175600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 22 1 . NN N . . . bcftools-1.21/test/norm.telomere.vcf000066400000000000000000000001521467060157400175250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 22 17 . NN N . . . bcftools-1.21/test/norm.vcf000066400000000000000000000122021467060157400157110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2;END=192 GT:DP 1/0:1 1/0:1 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4;END=114 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2;END=115 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2;END=100 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2;END=100 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2;END=294 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=;END=282 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 275 . A C,G 999 PASS INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0;END=18 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 25 . T TT,* 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 37 . C I 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0;END=22 GT:DP ./.:0 ./.:0 bcftools-1.21/test/overlap.0.out000066400000000000000000000004431467060157400166010ustar00rootroot00000000000000chr1 100 s1 A T . . . chr1 100 d4 AT A . . . chr1 100 i1 A ATTTT . . . chr1 101 s2 A T . . . chr1 101 i2 A AT . . . chr1 198 i3 A ATTTTT . . . chr1 199 s3 A T . . . chr1 199 d5f AT A . . . chr1 199 i4f A ATTTT . . . chr1 200 s4f A T . . . chr1 200 outd2 AT A . . . chr1 200 outi4 A AT . . . bcftools-1.21/test/overlap.1.out000066400000000000000000000006671467060157400166120ustar00rootroot00000000000000chr1 90 sv1 A ATGC . . END=100 chr1 90 sv2 A ATGC . . END=110 chr1 95 d1 AATGCATGCATGCATGCATGC A . . . chr1 98 d2 ATT A . . . chr1 99 d3 AT A . . . chr1 100 s1 A T . . . chr1 100 d4 AT A . . . chr1 100 i1 A ATTTT . . . chr1 101 s2 A T . . . chr1 101 i2 A AT . . . chr1 198 i3 A ATTTTT . . . chr1 199 s3 A T . . . chr1 199 d5f AT A . . . chr1 199 i4f A ATTTT . . . chr1 200 s4f A T . . . chr1 200 outd2 AT A . . . chr1 200 outi4 A AT . . . bcftools-1.21/test/overlap.2.out000066400000000000000000000006031467060157400166010ustar00rootroot00000000000000chr1 90 sv1 A ATGC . . END=100 chr1 90 sv2 A ATGC . . END=110 chr1 95 d1 AATGCATGCATGCATGCATGC A . . . chr1 98 d2 ATT A . . . chr1 99 d3 AT A . . . chr1 100 s1 A T . . . chr1 100 d4 AT A . . . chr1 100 i1 A ATTTT . . . chr1 101 s2 A T . . . chr1 101 i2 A AT . . . chr1 198 i3 A ATTTTT . . . chr1 199 s3 A T . . . chr1 199 d5f AT A . . . chr1 199 i4f A ATTTT . . . chr1 200 s4f A T . . . bcftools-1.21/test/overlap.neg0.out000066400000000000000000000006041467060157400172720ustar00rootroot00000000000000chr1 90 outsv1 A ATGC . . END=99 chr1 90 sv1 A ATGC . . END=100 chr1 90 sv2 A ATGC . . END=110 chr1 95 d1 AATGCATGCATGCATGCATGC A . . . chr1 98 outd1 AT A . . . chr1 98 d2 ATT A . . . chr1 98 outi1 A AT . . . chr1 99 outs1 A T . . . chr1 99 d3 AT A . . . chr1 99 outi2 A AT . . . chr1 99 outi3 A ATTTT . . . chr1 201 outs2 A T . . . chr1 201 outd3 AT A . . . chr1 201 outi5 A ATTTT . . . bcftools-1.21/test/overlap.neg1.out000066400000000000000000000003601467060157400172720ustar00rootroot00000000000000chr1 90 outsv1 A ATGC . . END=99 chr1 98 outd1 AT A . . . chr1 98 outi1 A AT . . . chr1 99 outs1 A T . . . chr1 99 outi2 A AT . . . chr1 99 outi3 A ATTTT . . . chr1 201 outs2 A T . . . chr1 201 outd3 AT A . . . chr1 201 outi5 A ATTTT . . . bcftools-1.21/test/overlap.neg2.out000066400000000000000000000004441467060157400172760ustar00rootroot00000000000000chr1 90 outsv1 A ATGC . . END=99 chr1 98 outd1 AT A . . . chr1 98 outi1 A AT . . . chr1 99 outs1 A T . . . chr1 99 outi2 A AT . . . chr1 99 outi3 A ATTTT . . . chr1 200 outd2 AT A . . . chr1 200 outi4 A AT . . . chr1 201 outs2 A T . . . chr1 201 outd3 AT A . . . chr1 201 outi5 A ATTTT . . . bcftools-1.21/test/overlap.vcf000066400000000000000000000017651467060157400164220ustar00rootroot00000000000000##fileformat=VCFv4.3 ##INFO= ##contig= ##bcftools_annotateVersion=1.13-36-gef5cf0a-dirty+htslib-1.13-19-g31bf087-dirty ##bcftools_annotateCommand=annotate -x FILTER events.vcf.txt; Date=Fri Sep 3 09:42:26 2021 #CHROM POS ID REF ALT QUAL FILTER INFO chr1 90 outsv1 A ATGC . . END=99 chr1 90 sv1 A ATGC . . END=100 chr1 90 sv2 A ATGC . . END=110 chr1 95 d1 AATGCATGCATGCATGCATGC A . . . chr1 98 outd1 AT A . . . chr1 98 d2 ATT A . . . chr1 98 outi1 A AT . . . chr1 99 outs1 A T . . . chr1 99 d3 AT A . . . chr1 99 outi2 A AT . . . chr1 99 outi3 A ATTTT . . . chr1 100 s1 A T . . . chr1 100 d4 AT A . . . chr1 100 i1 A ATTTT . . . chr1 101 s2 A T . . . chr1 101 i2 A AT . . . chr1 198 i3 A ATTTTT . . . chr1 199 s3 A T . . . chr1 199 d5f AT A . . . chr1 199 i4f A ATTTT . . . chr1 200 s4f A T . . . chr1 200 outd2 AT A . . . chr1 200 outi4 A AT . . . chr1 201 outs2 A T . . . chr1 201 outd3 AT A . . . chr1 201 outi5 A ATTTT . . . bcftools-1.21/test/parental-origin.1.out000066400000000000000000000000311467060157400202160ustar00rootroot00000000000000del maternal 34.580303 1 bcftools-1.21/test/parental-origin.2.out000066400000000000000000000000311467060157400202170ustar00rootroot00000000000000del maternal 32.899133 1 bcftools-1.21/test/parental-origin.3.out000066400000000000000000000000311467060157400202200ustar00rootroot00000000000000del maternal 32.889259 1 bcftools-1.21/test/parental-origin.4.out000066400000000000000000000000311467060157400202210ustar00rootroot00000000000000dup paternal 15.441653 1 bcftools-1.21/test/parental-origin.5.out000066400000000000000000000000311467060157400202220ustar00rootroot00000000000000dup maternal 15.441653 1 bcftools-1.21/test/parental-origin.vcf000066400000000000000000000013771467060157400200440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband father mother 20 100 . A C . . . GT:PL:AD 0/0:0,30,50:10,0 0/0:0,30,50:10,0 1/1:50,30,0:0,10 20 101 . A C . . . GT:PL:AD 0/0:0,30,50:10,0 0/1:30,0,50:10,0 1/1:50,30,0:0,10 20 102 . A C . . . GT:PL:AD 1/1:50,30,0:10,0 0/1:30,0,50:10,0 0/0:0,30,50:0,10 20 103 . A C . . . GT:PL:AD 0/1:30,0,50:7,3 0/0:0,30,50:10,0 0/1:30,0,50:5,5 20 104 . A C . . . GT:PL:AD 0/1:30,0,50:3,7 0/0:0,30,50:10,0 0/1:30,0,50:5,5 bcftools-1.21/test/perl-flt.vcf000066400000000000000000000064461467060157400165000ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##reference=file://some/path/human_g1k_v37.fasta ##INFO= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SmplAAA SmplBBB 1 90 . C T . . CSQ=5_prime_utr|XYZ|ENST00000000001|protein_coding GT 1|0 1|1 1 102 . C T 1 . CSQ=synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T GT 1|0 1|0 1 103 . G A 1 . CSQ=missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A GT 1|0 0|0 1 103 . G C 1 . CSQ=missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C GT 0|0 1|0 1 107 . G A 1 . CSQ=missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A GT 1|0 1|0 1 108 . T A 1 . CSQ=splice_region|XYZ|ENST00000000001|protein_coding,@107 GT 1|0 1|0 1 121 . ACG A . . CSQ=inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 1|0 1 124 . TA T . . CSQ=@121 GT 1|0 1|0 1 128 . T C 1 . CSQ=missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0/0 1 129 . A C 1 . CSQ=splice_region|XYZ|ENST00000000001|protein_coding,@128 GT 1|0 0/0 1 140 . TA AACG . . CSQ=inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 1 142 . C CC . . CSQ=splice_region|XYZ|ENST00000000001|protein_coding,@140 GT 1|0 0|0 1 145 . AC TA . . CSQ=stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA GT 1|0 0|0 1 160 . TA T . . CSQ=*frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 1 190 . C T . . CSQ=3_prime_utr|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 2 97 . A C . . CSQ=3_prime_utr|ABC|ENST00000000002|protein_coding GT 1|0 0|0 2 105 . AC A . . CSQ=@121 GT 1|0 0|0 2 121 . AC A . . CSQ=frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A,splice_region|ABC|ENST00000000002|protein_coding GT 1|0 0|0 2 126 . C CTT . . CSQ=@127 GT 1|0 0|0 2 127 . G GG . . CSQ=inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG GT 1|0 0|0 2 144 . TAC T . . CSQ=@148 GT 1|0 0|0 2 148 . TA T . . CSQ=inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding GT 1|0 0|0 2 164 . T G . . CSQ=missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G GT 1|0 0|0 2 165 . A C . . CSQ=synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C GT 1|0 0|0 2 169 . A G . . CSQ=@170 GT 1|0 0|0 2 170 . C T . . CSQ=missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T GT 1|0 0|0 2 199 . G T . . CSQ=5_prime_utr|ABC|ENST00000000002|protein_coding GT 1|0 0|0 3 20 . T A . . CSQ=non_coding|mir-007||lincRNA GT 1|0 0|0 3 109 . ACGTACGT A 1 . CSQ=splice_acceptor|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 3 113 . A T . . CSQ=splice_region|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 3 120 . T A . . CSQ=intron|QWRTY||protein_coding GT 1|0 0|0 3 152 . T A . . CSQ=splice_region|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 3 159 . G A . . CSQ=splice_donor|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 bcftools-1.21/test/plugin-missing2ref.out.vcf000066400000000000000000000041551467060157400213000ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= ##bcftools_pluginCommand=plugin missing2ref -o test.out.vcf -- missing2ref -p -m #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 3000150 . C T 59.2 PASS . GT:GQ 1|1:245 1|1:245 0/1:245 1/1:245 1 3000151 . C T 59.2 PASS . GT:DP:GQ 0|0:32:245 0|0:32:245 0|0:32:245 0|0:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 2/2:0,1:409:35:-20,-5,-20,-20,-5,-20 2|2:0,1:409:35:-20,-5,-20,-20,-5,-20 2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP 0|0:322:26 0|0:322:26 0|0:322:26 0|0:322:26 3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP 0|0:91:26 0|0:91:26 0|0:91:26 0|0:91:26 4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP 0|0:325:31 0|0:325:31 0|0:325:31 0|0:325:31 bcftools-1.21/test/plugin-missing2ref.vcf000066400000000000000000000040061467060157400204650ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 ./.:245 0/1:245 1/1:245 1 3000151 . C T 59.2 PASS . GT:DP:GQ ./.:32:245 ./.:32:245 0|0:32:245 0|0:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 2/2:0,1:409:35:-20,-5,-20 ./.:0,1:409:35:-20,-5,-20 2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 ./.:322:26 ./.:322:26 3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 ./.:91:26 ./.:91:26 4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 ./.:325:31 ./.:325:31 bcftools-1.21/test/plugin1.vcf000066400000000000000000000043351467060157400163250ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 ./.:245 1 3000151 . C T 59.2 PASS . GT:DP:GQ ./.:32:245 ./.:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS . GT:GQ:DP ./.:245:32 ./.:245:32 1 3106154 . C CT 59.2 PASS . GT:GQ:DP ./.:245:32 ./.:245:32 1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS . GT:GQ:DP ./.:212:22 ./.:212:22 1 3177144 . G T 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 1 3177144 . G . 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP ./.:12:10 ./.:12:10 2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 bcftools-1.21/test/prune.1.1.out000066400000000000000000000031771467060157400164310ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 102 . T A . . AF=0.2;POS_R2=101;POS_LD=101;POS_HD=101;R2=1;LD=1;HD=0 GT 0/1 0/1 0/1 1 103 . T A . . AF=0.1;POS_R2=102;POS_LD=102;POS_HD=102;R2=0.105235;LD=0.145076;HD=0 GT 0/1 0/0 0/0 1 104 . T A . . AF=0.3;POS_R2=103;POS_LD=103;POS_HD=103;R2=0.105235;LD=0;HD=0 GT 0/0 0/0 0/0 1 105 . T A . . AF=0.2;POS_R2=104;POS_LD=104;POS_HD=104;R2=1;LD=0;HD=0 GT 0/0 0/0 0/0 1 106 . T A . . AF=0.1;POS_R2=105;POS_LD=105;POS_HD=105;R2=0.755358;LD=0;HD=0 GT 0/1 1/1 1/1 1 107 . T A . . AF=0.3;POS_R2=106;POS_LD=106;POS_HD=106;R2=0.25;LD=0.790569;HD=-0.0208333 GT 0/1 0/0 0/1 1 108 . T A . . AF=0.2;POS_R2=107;POS_LD=107;POS_HD=107;R2=1;LD=1;HD=-0.0416667 GT 0/1 1/1 0/1 bcftools-1.21/test/prune.1.2.out000066400000000000000000000020621467060157400164220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= ##FILTER= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 102 . T A . MaxR2 AF=0.2;POS_R2=101;R2=1 GT 0/1 0/1 0/1 1 103 . T A . . AF=0.1;POS_R2=101;R2=0.105235 GT 0/1 0/0 0/0 1 104 . T A . MaxR2 AF=0.3;POS_R2=102;R2=1 GT 0/0 0/0 0/0 1 105 . T A . MaxR2 AF=0.2;POS_R2=104;R2=1 GT 0/0 0/0 0/0 1 106 . T A . MaxR2 AF=0.1;POS_R2=104;R2=0.755358 GT 0/1 1/1 1/1 1 107 . T A . . AF=0.3;POS_R2=105;R2=0.32665 GT 0/1 0/0 0/1 1 108 . T A . MaxR2 AF=0.2;POS_R2=107;R2=1 GT 0/1 1/1 0/1 bcftools-1.21/test/prune.1.3.out000066400000000000000000000012571467060157400164300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 103 . T A . . AF=0.1;POS_R2=101;R2=0.105235 GT 0/1 0/0 0/0 1 107 . T A . . AF=0.3;POS_R2=101;R2=0.32665 GT 0/1 0/0 0/1 bcftools-1.21/test/prune.1.4.out000066400000000000000000000007521467060157400164300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 104 . T A . . AF=0.3 GT 0/0 0/0 0/0 1 105 . T A . . AF=0.2 GT 0/0 0/0 0/0 1 107 . T A . . AF=0.3 GT 0/1 0/0 0/1 bcftools-1.21/test/prune.1.5.out000066400000000000000000000007521467060157400164310ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 103 . T A . . AF=0.1 GT 0/1 0/0 0/0 1 107 . T A . . AF=0.3 GT 0/1 0/0 0/1 1 108 . T A . . AF=0.2 GT 0/1 1/1 0/1 bcftools-1.21/test/prune.1.6.out000066400000000000000000000007521467060157400164320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 103 . T A . . AF=0.1 GT 0/1 0/0 0/0 1 105 . T A . . AF=0.2 GT 0/0 0/0 0/0 1 107 . T A . . AF=0.3 GT 0/1 0/0 0/1 bcftools-1.21/test/prune.1.7.out000066400000000000000000000007521467060157400164330ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 102 . T A . . AF=0.2 GT 0/1 0/1 0/1 1 104 . T A . . AF=0.3 GT 0/0 0/0 0/0 1 105 . T A . . AF=0.2 GT 0/0 0/0 0/0 1 108 . T A . . AF=0.2 GT 0/1 1/1 0/1 bcftools-1.21/test/prune.1.vcf000066400000000000000000000011161467060157400162300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 1 101 . T A . . AF=0.3 GT 0/1 0/1 0/1 1 102 . T A . . AF=0.2 GT 0/1 0/1 0/1 1 103 . T A . . AF=0.1 GT 0/1 0/0 0/0 1 104 . T A . . AF=0.3 GT 0/0 0/0 0/0 1 105 . T A . . AF=0.2 GT 0/0 0/0 0/0 1 106 . T A . . AF=0.1 GT 0/1 1/1 1/1 1 107 . T A . . AF=0.3 GT 0/1 0/0 0/1 1 108 . T A . . AF=0.2 GT 0/1 1/1 0/1 bcftools-1.21/test/prune.2.1.out000066400000000000000000000025721467060157400164300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 s4 s5 s6 s7 s8 s9 s10 s11 s12 s13 s14 s15 s16 s17 s18 s19 s20 1 101 . T A . . . GT 0/1 ./. 0/0 ./. 0/1 ./. 0/0 0/1 0/0 0/0 0/1 1/1 0/0 0/1 0/1 0/0 ./. 0/1 0/1 ./. 1 102 . T A . . POS_R2=101;POS_LD=101;POS_HD=101;R2=0.363372;LD=0.487431;HD=0.0520833 GT 0/1 0/1 0/0 0/1 0/0 0/1 0/1 0/1 0/1 0/0 0/1 1/1 0/1 1/1 0/1 0/0 0/1 0/1 0/1 1/1 1 103 . T A . . POS_R2=102;POS_LD=102;POS_HD=102;R2=0.0990065;LD=0.24274;HD=0.0202381 GT 0/1 0/1 0/0 0/1 0/0 0/1 0/1 0/1 0/1 0/0 0/1 0/0 0/1 0/1 0/1 0/0 0/1 0/1 0/1 0/0 bcftools-1.21/test/prune.2.vcf000066400000000000000000000011111467060157400162240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT s1 s2 s3 s4 s5 s6 s7 s8 s9 s10 s11 s12 s13 s14 s15 s16 s17 s18 s19 s20 1 101 . T A . . . GT 0/1 ./. 0/0 ./. 0/1 ./. 0/0 0/1 0/0 0/0 0/1 1/1 0/0 0/1 0/1 0/0 ./. 0/1 0/1 ./. 1 102 . T A . . . GT 0/1 0/1 0/0 0/1 0/0 0/1 0/1 0/1 0/1 0/0 0/1 1/1 0/1 1/1 0/1 0/0 0/1 0/1 0/1 1/1 1 103 . T A . . . GT 0/1 0/1 0/0 0/1 0/0 0/1 0/1 0/1 0/1 0/0 0/1 0/0 0/1 0/1 0/1 0/0 0/1 0/1 0/1 0/0 bcftools-1.21/test/query.10.out000066400000000000000000000000201467060157400163460ustar00rootroot000000000000003258449 1/1 0/1 bcftools-1.21/test/query.11.out000066400000000000000000000000401467060157400163510ustar00rootroot000000000000003062915 0/1 0/2 3258449 1/1 0/1 bcftools-1.21/test/query.12.out000066400000000000000000000010031467060157400163520ustar00rootroot00000000000000I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. .:.:.:. .:.:.:. I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. .:.:.:. .:.:.:. I8=. I16=. I32=. IF=. IA8=10,. IA16=1000,. IA32=100000,. IAF=0.003,. IA8=. IA16=. IA32=. IAF=. 10:1000:100000:0.003 .:.:.:. I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. 10:1000:100000:0.003 .:.:.:. I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. 10:1000:100000:0.003 .:.:.:. bcftools-1.21/test/query.13.out000066400000000000000000000000601467060157400163550ustar00rootroot000000000000003000151 A 1 3000152 B 1 3000153 A 1 3000153 B 1 bcftools-1.21/test/query.14.out000066400000000000000000000000601467060157400163560ustar00rootroot000000000000003000150 A 0 3000150 B 0 3000151 B 0 3000152 A 0 bcftools-1.21/test/query.15.out000066400000000000000000000000601467060157400163570ustar00rootroot000000000000003000150 A 0 3000150 B 0 3000151 B 0 3000152 A 0 bcftools-1.21/test/query.16.out000066400000000000000000000000601467060157400163600ustar00rootroot000000000000003000151 A 1 3000152 B 1 3000153 A 1 3000153 B 1 bcftools-1.21/test/query.17.out000066400000000000000000000000101467060157400163540ustar00rootroot000000000000001 2 3 4 bcftools-1.21/test/query.18.out000066400000000000000000000000241467060157400163620ustar00rootroot000000000000003000002 . 3000003 . bcftools-1.21/test/query.19.out000066400000000000000000000000401467060157400163610ustar00rootroot000000000000003000001 11 3000004 11 3000005 1 bcftools-1.21/test/query.2.out000066400000000000000000000000171467060157400162750ustar00rootroot000000000000001111,2222,3333 bcftools-1.21/test/query.2.vcf000066400000000000000000000012271467060157400162500ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D 1 3062915 . GTTT G 48.7 . XX_A=1;XX.A=2;XX.A0=3;xx.a0=4 GT 0/1 0/1 bcftools-1.21/test/query.20.out000066400000000000000000000000241467060157400163530ustar00rootroot000000000000003000002 . 3000003 . bcftools-1.21/test/query.21.out000066400000000000000000000000421467060157400163540ustar00rootroot000000000000003000001 1.1 3000004 1.1 3000005 1 bcftools-1.21/test/query.22.out000066400000000000000000000000241467060157400163550ustar00rootroot000000000000003000002 . 3000003 . bcftools-1.21/test/query.23.out000066400000000000000000000000431467060157400163570ustar00rootroot000000000000003000001 xxx 3000004 xxx 3000005 .. bcftools-1.21/test/query.24.out000066400000000000000000000000411467060157400163560ustar00rootroot000000000000003000003 . 3000004 xxx 3000005 .. bcftools-1.21/test/query.25.out000066400000000000000000000020431467060157400163630ustar00rootroot000000000000001 3062915 id3D GTTT G 48.7 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 1 3062915 idSNP G C,T 419 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:109:35:-10,-5,-20,-20,-5,-20 1 3062915 id2D GTT G 999 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 1 3106154 . CAAA C 72.6 PASS AN=0;AC=0 GT:GQ:DP .:245:32 ./.:145:22 1 3106154 . C CT 459 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:145:22 1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:11:11 1 3162006 . GAA G 206 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:112:12 1 3177144 . G . 364 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:20 1 3184885 . TAAAA TA,T 8.42 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:22:20 1/2:12:10 2 3199812 . G GTT,GT 291 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:122:16 3 3212016 . CTT C,CT 52.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:11:16 4 3258448 . TACACACAC T 123 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:125:11 4 3258449 . 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PASS A B bcftools-1.21/test/query.91.out000066400000000000000000000000041467060157400163610ustar00rootroot00000000000000 12 bcftools-1.21/test/query.92.out000066400000000000000000000002041467060157400163640ustar00rootroot000000000000003000151 0/0 A 10,0,0 3000151 0/0 B 10,0,0 3000155 0/2 A 20,0,10 3000155 0/2 B 200,0,10 3000157 1/2 A 0,40,10 3000157 1/2 B 0,400,10 bcftools-1.21/test/query.93.out000066400000000000000000000000551467060157400163710ustar00rootroot000000000000003000153 2/2 B 0,0,210 3000155 0/2 B 200,0,10 bcftools-1.21/test/query.94.out000066400000000000000000000001011467060157400163620ustar00rootroot000000000000003000154 0/1 A 30,13,0 3000156 1/0 A 30,14,0 3000158 2/0 A 0,5,30 bcftools-1.21/test/query.95.out000066400000000000000000000001161467060157400163710ustar00rootroot00000000000000#[1]CHROM [2]POS [3]SAMPLE [4]DP [5]GT 4 3258449 C 1 1/1 4 3258449 D 0 0/0 bcftools-1.21/test/query.96.out000066400000000000000000000002141467060157400163710ustar00rootroot00000000000000#[1]C:CHROM [2]C:POS [3]C:SAMPLE [4]C:DP [5]C:GT [6]D:CHROM [7]D:POS [8]D:SAMPLE [9]D:DP [10]D:GT 4 3258449 C 1 1/1 4 3258449 D 0 0/0 bcftools-1.21/test/query.97.out000066400000000000000000000001431467060157400163730ustar00rootroot00000000000000#[1]CHROM [2]POS [3]C:SAMPLE [4]C:DP [5]C:GT [6]D:SAMPLE [7]D:DP [8]D:GT 4 3258449 C 1 1/1 D 0 0/0 bcftools-1.21/test/query.98.2.out000066400000000000000000000001131467060157400165310ustar00rootroot00000000000000#CHROM POS C:SAMPLE D:SAMPLE C:DP D:DP C:GT D:GT 4 3258449 C D 1 0 1/1 0/0 bcftools-1.21/test/query.98.out000066400000000000000000000001431467060157400163740ustar00rootroot00000000000000#[1]CHROM [2]POS [3]C:SAMPLE [4]D:SAMPLE [5]C:DP [6]D:DP [7]C:GT [8]D:GT 4 3258449 C D 1 0 1/1 0/0 bcftools-1.21/test/query.99.out000066400000000000000000000000211467060157400163700ustar00rootroot0000000000000011 2343543 N . . bcftools-1.21/test/query.add-variantkey.vcf000066400000000000000000000507001467060157400210120ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##fileDate=20151104 ##source=dbSNP ##dbSNP_BUILD_ID=146 ##reference=GRCh37.p13 ##phasing=partial ##variationPropertyDocumentationUrl=ftp://ftp.ncbi.nlm.nih.gov/snp/specs/dbSNP_BitField_latest.pdf ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO=SubSNP->Batch.link_out"> ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO=5% minor allele frequency in each and all populations"> ##INFO=5% minor allele frequency in 1+ populations"> ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##INFO= ##INFO== 1% and for which 2 or more founders contribute to that minor allele frequency."> ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10019 rs775809821 TA T . . RS=775809821;RSPOS=10020;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800139110e60000;RSX=2e3deb1d 1 10055 rs768019142 T TA . . RS=768019142;RSPOS=10055;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013a309780000;RSX=2dc70ac6 1 10108 rs62651026 C T . . RS=62651026;RSPOS=10108;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013bd88b80000;RSX=03bbfa92 1 10109 rs376007522 A T . . RS=376007522;RSPOS=10109;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013be08980000;RSX=16696b62 1 10128 rs796688738 A AC . . RS=796688738;RSPOS=10128;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013c789020000;RSX=2f7c8162 1 10139 rs368469931 A T . . RS=368469931;RSPOS=10139;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013cd08980000;RSX=15f667ab 1 10144 rs144773400 TA T . . RS=144773400;RSPOS=10145;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013cf90e60000;RSX=08a11118 1 10146 rs779258992 AC A . . RS=779258992;RSPOS=10147;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013d090880000;RSX=2e728c70 1 10150 rs371194064 C T . . RS=371194064;RSPOS=10150;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013d288b80000;RSX=161ff8d0 1 10165 rs796884232 A AC . . RS=796884232;RSPOS=10165;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013da09020000;RSX=2f7f7d08 1 10177 rs201752861 A C . . RS=201752861;RSPOS=10177;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013e008880000;RSX=0c06811d 1 10177 rs367896724 A AC . . RS=367896724;RSPOS=10177;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005170026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;G5A;G5;KGPhase3;CAF=0.5747,0.4253;COMMON=1;VKX=080013e009020000;RSX=15eda894 1 10180 rs201694901 T C . . RS=201694901;RSPOS=10180;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013e188e80000;RSX=0c059eb5 1 10228 rs143255646 TA T . . RS=143255646;RSPOS=10229;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013f990e60000;RSX=0889e85e 1 10228 rs200462216 TAACCCCTAACCCTAACCCTAAACCCTA T . . RS=200462216;RSPOS=10229;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013f9a00e1d03;RSX=0bf2cf88 1 10230 rs775928745 AC A . . RS=775928745;RSPOS=10231;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=080013fa90880000;RSX=2e3fbba9 1 10231 rs200279319 C A . . RS=200279319;RSPOS=10231;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013fb08a00000;RSX=0bf00517 1 10234 rs145599635 C T . . RS=145599635;RSPOS=10234;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080013fc88b80000;RSX=08adac93 1 10235 rs540431307 T TA . . RS=540431307;RSPOS=10235;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;KGPhase3;CAF=0.9988,0.001198;COMMON=0;VKX=080013fd09780000;RSX=203653cb 1 10247 rs796996180 T C . . RS=796996180;RSPOS=10247;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800140308e80000;RSX=2f813254 1 10248 rs148908337 A T . . RS=148908337;RSPOS=10248;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800140388980000;RSX=08e02931 1 10249 rs774211241 AAC A . . RS=774211241;RSPOS=10250;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800140418820000;RSX=2e2586a9 1 10250 rs199706086 A C . . RS=199706086;RSPOS=10250;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800140488880000;RSX=0be745e6 1 10254 rs140194106 TA T . . RS=140194106;RSPOS=10255;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800140690e60000;RSX=085b313a 1 10257 rs111200574 A C . . RS=111200574;RSPOS=10257;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050100020005000102000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;SLO;R5;ASP;GNO;VKX=0800140808880000;RSX=06a0c93e 1 10259 rs200940095 C A . . RS=200940095;RSPOS=10259;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800140908a00000;RSX=0bfa1a3f 1 10291 rs145427775 C T . . RS=145427775;RSPOS=10291;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800141908b80000;RSX=08ab0d3f 1 10327 rs112750067 T C . . RS=112750067;RSPOS=10327;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800142b08e80000;RSX=06b86df3 1 10328 rs201106462 AACCCCTAACCCTAACCCTAACCCT A . . RS=201106462;RSPOS=10329;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800142b90367897;RSX=0bfca41e 1 10329 rs150969722 AC A . . RS=150969722;RSPOS=10330;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800142c10880000;RSX=08ff9d7a 1 10352 rs555500075 T TA . . RS=555500075;RSPOS=10352;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005170026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;G5A;G5;KGPhase3;CAF=0.5625,0.4375;COMMON=1;VKX=0800143789780000;RSX=211c422b 1 10352 rs145072688 T TA . . RS=145072688;RSPOS=10353;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;CAF=0.5625,0.4375;COMMON=1;VKX=0800143789780000;RSX=08a5a230 1 10383 rs147093981 A AC . . RS=147093981;RSPOS=10383;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800144709020000;RSX=08c479dd 1 10389 rs766767872 AC A . . RS=766767872;RSPOS=10390;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800144a10880000;RSX=2db3f300 1 10433 rs56289060 A AC . . RS=56289060;RSPOS=10433;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800146009020000;RSX=035ae724 1 10439 rs112766696 AC A . . RS=112766696;RSPOS=10440;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050100020005000102000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;SLO;R5;ASP;GNO;VKX=0800146310880000;RSX=06b8aee8 1 10440 rs112155239 C A . . RS=112155239;RSPOS=10440;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800146388a00000;RSX=06af5a67 1 10458 rs796546892 A AC . . RS=796546892;RSPOS=10458;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VKX=0800146c89020000;RSX=2f7a574c 1 10469 rs370233998 C G . . RS=370233998;RSPOS=10469;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147208b00000;RSX=1611528e 1 10478 rs528916756 C G . . RS=528916756;RSPOS=10478;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147688b00000;RSX=1f86a114 1 10483 rs547662686 C T . . RS=547662686;RSPOS=10483;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147908b80000;RSX=20a4ab5e 1 10490 rs565971701 G A . . RS=565971701;RSPOS=10490;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147c88c00000;RSX=21bc0af5 1 10492 rs55998931 C T . . RS=55998931;RSPOS=10492;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147d88b80000;RSX=035679d3 1 10493 rs199606420 C A . . RS=199606420;RSPOS=10493;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147e08a00000;RSX=0be5c094 1 10493 rs199606420 C G . . RS=199606420;RSPOS=10493;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800147e08b00000;RSX=0be5c094 1 10505 rs548419688 A T . . RS=548419688;RSPOS=10505;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0;VKX=0800148408980000;RSX=20b03868 1 10506 rs568405545 C G . . RS=568405545;RSPOS=10506;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0;VKX=0800148488b00000;RSX=21e12e29 1 10511 rs534229142 G A . . RS=534229142;RSPOS=10511;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0;VKX=0800148708c00000;RSX=1fd7b096 1 10519 rs62636508 G C . . RS=62636508;RSPOS=10519;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800148b08c80000;RSX=03bbc1dc 1 10539 rs537182016 C A . . RS=537182016;RSPOS=10539;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040026000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.9994,0.000599;COMMON=0;VKX=0800149508a00000;RSX=2004bf40 1 10542 rs572818783 C T . . RS=572818783;RSPOS=10542;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0;VKX=0800149688b80000;RSX=2224855f 1 10579 rs538322974 C A . . RS=538322974;RSPOS=10579;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0;VKX=080014a908a00000;RSX=2016281e 1 10583 rs58108140 G A . . RS=58108140;RSPOS=10583;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000016000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase1;VKX=080014ab08c00000;RSX=0376a8ec 1 10603 rs200782791 G A . . RS=200782791;RSPOS=10603;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=080014b508c00000;RSX=0bf7b3c7 1 10611 rs189107123 C G . . RS=189107123;RSPOS=10611;dbSNPBuildID=135;SSR=0;SAO=0;VP=0x050000020005000014000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase1;VKX=080014b908b00000;RSX=0b458bb3 1 10616 rs376342519 CCGCCGTTGCAAAGGCGCGCCG C . . RS=376342519;RSPOS=10617;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;KGPhase3;CAF=0.006989,0.993;COMMON=1;VKX=080014bb8ad3d64f;RSX=166e87f7 1 10642 rs558604819 G A . . RS=558604819;RSPOS=10642;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.9958,0.004193;COMMON=1;VKX=080014c888c00000;RSX=214ba213 1 10828 rs10218492 G A . . RS=10218492;RSPOS=10828;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800152588c00000;RSX=009bebfc 1 10904 rs10218493 G A . . RS=10218493;RSPOS=10904;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000102000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;GNO;VKX=0800154b88c00000;RSX=009bebfd 1 10927 rs10218527 A G . . RS=10218527;RSPOS=10927;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800155708900000;RSX=009bec1f 1 10938 rs28853987 G A . . RS=28853987;RSPOS=10938;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800155c88c00000;RSX=01b846e3 1 11008 rs575272151 C G . . RS=575272151;RSPOS=11008;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005150024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;G5;KGPhase3;CAF=0.9119,0.08806;COMMON=1;VKX=0800157f88b00000;RSX=2249f4d7 1 11012 rs544419019 C G . . RS=544419019;RSPOS=11012;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005150024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;G5;KGPhase3;CAF=0.9119,0.08806;COMMON=1;VKX=0800158188b00000;RSX=20732ccb 1 11014 rs28484712 G A . . RS=28484712;RSPOS=11014;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800158288c00000;RSX=01b2a468 1 11022 rs28775022 G A . . RS=28775022;RSPOS=11022;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VKX=0800158688c00000;RSX=01b7126e 1 11063 rs561109771 T G . . 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NUM_TAG=1,2,3;STR_TAG=x,y,z bcftools-1.21/test/query.filter.11.vcf000066400000000000000000000003731467060157400176150ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 10 . G T . . . GT 0/0 0/0 1 11 . G T . . . GT 0/0 1/1 1 12 . G T . . . GT 1/1 1/1 bcftools-1.21/test/query.filter.12.vcf000066400000000000000000000004471467060157400176200ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 0 1 2 3 1 1001 . A C,G,T . . . GT 0/0 1/1 2/2 ./. 1 1002 . A C,G,T . . . GT ./0 ./1 2/2 ./. 1 1003 . A C,G,T . . . GT 0/. 1/1 ./2 3/3 bcftools-1.21/test/query.filter.13.vcf000066400000000000000000000004161467060157400176150ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=test.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 22 16053659 . A C,T 352 . . AD 0,9,1 22 16053791 . C A,T 287 . . AD 4,4,1 bcftools-1.21/test/query.filter.2.vcf000066400000000000000000000011251467060157400175310ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3000150 . C T,A 59.2 PASS . GT ./. 1 3000151 . C T,A 59.2 PASS . GT 0/0 1 3000152 . C T,A 59.2 PASS . GT 0/1 1 3000153 . C T,A 59.2 PASS . GT 0/2 1 3000154 . C T,A 59.2 PASS . GT 1/0 1 3000155 . C T,A 59.2 PASS . GT 1/1 1 3000156 . C T,A 59.2 PASS . GT 1/2 1 3000157 . C T,A 59.2 PASS . GT 2/0 1 3000158 . C T,A 59.2 PASS . GT 2/2 bcftools-1.21/test/query.filter.3.vcf000066400000000000000000000011731467060157400175350ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T,A 59.2 PASS . GT ./. ./. 1 3000151 . C T,A 59.2 PASS . GT 0/0 1/0 1 3000152 . C T,A 59.2 PASS . GT 0/1 1/1 1 3000153 . C T,A 59.2 PASS . GT 0/2 1/2 1 3000154 . C T,A 59.2 PASS . GT 1/0 1/0 1 3000155 . C T,A 59.2 PASS . GT 1/1 1/1 1 3000156 . C T,A 59.2 PASS . GT 1/2 1/2 1 3000157 . C T,A 59.2 PASS . GT 2/0 1/0 1 3000158 . C T,A 59.2 PASS . GT 2/2 1/2 bcftools-1.21/test/query.filter.4.vcf000066400000000000000000000011731467060157400175360ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T,A 59.2 PASS . GT ./. ./. 1 3000151 . CCC C 59.2 PASS . GT 0/0 1/0 1 3000152 . C T,* 59.2 PASS . GT 0/1 1/2 1 3000153 . C T,* 59.2 PASS . GT 0/1 1/2 1 3000154 . C T,A 59.2 PASS . GT 1/0 1/0 1 3000155 . C T,A 59.2 PASS . GT 1/1 1/1 1 3000156 . C T,A 59.2 PASS . GT 1/2 1/2 1 3000157 . C T,A 59.2 PASS . GT 2/0 1/0 1 3000158 . C T,A 59.2 PASS . GT 2/2 1/2 bcftools-1.21/test/query.filter.5.vcf000066400000000000000000000021551467060157400175400ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##FORMAT= ##INFO= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T,A 59.2 PASS AD=0,0,0 GT:AD ./.:0,0,0 ./.:0,0,0 1 3000151 . C T,A 59.2 PASS AD=10,0,0 GT:AD 0/0:10,0,0 0/0:010,0,0 1 3000152 . C T,A 59.2 PASS AD=0,11,0 GT:AD 1/1:0,11,0 1/1:0,110,0 1 3000153 . C T,A 59.2 PASS AD=0,0,21 GT:AD 2/2:0,0,20 2/2:0,0,210 1 3000154 . C T,A 59.2 PASS AD=30,13,0 GT:AD 0/1:30,13,0 0/1:300,13,0 1 3000155 . C T,A 59.2 PASS AD=20,0,10 GT:AD 0/2:20,0,10 0/2:200,0,10 1 3000156 . C T,A 59.2 PASS AD=30,14,0 GT:AD 1/0:30,14,0 1/0:300,14,0 1 3000157 . C T,A 59.2 PASS AD=0,40,10 GT:AD 1/2:0,40,10 1/2:0,400,10 1 3000158 . C T,A 59.2 PASS AD=0,5,30 GT:AD 2/0:0,5,30 2/0:0,5,300 1 3000158 . C T,A 59.2 PASS AD=0,110,30 GT:AD 2/0:1,0,110 2/0:1,0,1100 bcftools-1.21/test/query.filter.6.vcf000066400000000000000000000007061467060157400175410ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO 1 16777215 . C T . . . 1 16777216 . C T . . . 1 16777217 . C T . . . 1 33554432 . C T . . . 1 33554433 . C T . . . 1 33554434 . C T . . . 1 33554435 . C T . . . 1 33554436 . C T . . . 1 118673904 . CACCT *,CCCT . . . 1 118673906 . C CACA,CACACA,CACACACA . . . bcftools-1.21/test/query.filter.7.vcf000066400000000000000000000006071467060157400175420ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 100 . C T . . II=1,2,3 FI 1,2,3 1 1 101 . C T . . II=4,5,6 FI 4,5,6 1 bcftools-1.21/test/query.filter.8.vcf000066400000000000000000000004571467060157400175460ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 100 . C CTT . . ILEN=1 1 101 . C CT . . ILEN=2 bcftools-1.21/test/query.filter.9.vcf000066400000000000000000000005141467060157400175410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 1 . GAAAA GAAA,G . PASS . AD 1,2,3 3,2,1 1 2 . A AAAT,AAAGGATGGTAT . PASS . AD 5,6,7 7,6,5 bcftools-1.21/test/query.filter.id.1.out000066400000000000000000000000201467060157400201450ustar00rootroot00000000000000rs123 ss124;abc bcftools-1.21/test/query.filter.id.2.out000066400000000000000000000000061467060157400201520ustar00rootroot00000000000000rs123 bcftools-1.21/test/query.filter.id.3.out000066400000000000000000000000121467060157400201500ustar00rootroot00000000000000ss124;abc bcftools-1.21/test/query.filter.id.3.txt000066400000000000000000000000041467060157400201610ustar00rootroot00000000000000abc bcftools-1.21/test/query.filter.id.4.out000066400000000000000000000000101467060157400201470ustar00rootroot00000000000000rs123 . bcftools-1.21/test/query.filter.id.vcf000066400000000000000000000003121467060157400177610ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 123 rs123 A . . . . 1 124 ss124;abc A . . . . 1 125 . A . . . . bcftools-1.21/test/query.filter.vcf000066400000000000000000000022451467060157400173750ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS . GT 0 0 1 3000151 . C T 59.2 PASS . GT 1 0 1 3000152 . C T 59.2 PASS . GT 0 1 1 3000153 . C T 59.2 PASS . GT 1 1 bcftools-1.21/test/query.gtidx.1.out000066400000000000000000000000371467060157400174140ustar00rootroot000000000000001/2 A,B,C AA,BB,CC 0,1,2 0,1,2 bcftools-1.21/test/query.gtidx.1.vcf000066400000000000000000000010641467060157400173640ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE 1 1 . CAA C,CA . . . GT:TC:TS:TI:TF 1/2:A,B,C:AA,BB,CC:0,1,2:0,1,2 1 2 . CAA C,CA . . . GT:TC:TS:TI:TF 2/2:A,B:AA,BB:0,1:0,1 bcftools-1.21/test/query.gtidx.2.out000066400000000000000000000000101467060157400174040ustar00rootroot000000000000002/2 0,1 bcftools-1.21/test/query.header.vcf000066400000000000000000000004551467060157400173410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##contig= ##reference=ref.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D 4 3258449 . A C . . . GT:DP 1/1:1 0/0:0 bcftools-1.21/test/query.negative.vcf000066400000000000000000000036441467060157400177160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##INFO= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO 1 120 . C A . . TAGV1=-120;TAGV2=-120,-120;TAG1=-120;TAG2=-120,-120 1 121 . C A . . TAGV1=-121;TAGV2=-121,-121;TAG1=-121;TAG2=-121,-121 1 122 . C A . . TAGV1=-122;TAGV2=-122,-122;TAG1=-122;TAG2=-122,-122 1 123 . C A . . TAGV1=-123;TAGV2=-123,-123;TAG1=-123;TAG2=-123,-123 1 124 . C A . . TAGV1=-124;TAGV2=-124,-124;TAG1=-124;TAG2=-124,-124 1 125 . C A . . TAGV1=-125;TAGV2=-125,-125;TAG1=-125;TAG2=-125,-125 1 126 . C A . . TAGV1=-126;TAGV2=-126,-126;TAG1=-126;TAG2=-126,-126 1 127 . C A . . TAGV1=-127;TAGV2=-127,-127;TAG1=-127;TAG2=-127,-127 1 128 . C A . . TAGV1=-128;TAGV2=-128,-128;TAG1=-128;TAG2=-128,-128 1 129 . C A . . TAGV1=-129;TAGV2=-129,-129;TAG1=-129;TAG2=-129,-129 1 32760 . C A . . TAGV1=-32760;TAGV2=-32760,-32760;TAG1=-32760;TAG2=-32760,-32760 1 32761 . C A . . TAGV1=-32761;TAGV2=-32761,-32761;TAG1=-32761;TAG2=-32761,-32761 1 32762 . C A . . TAGV1=-32762;TAGV2=-32762,-32762;TAG1=-32762;TAG2=-32762,-32762 1 32763 . C A . . TAGV1=-32763;TAGV2=-32763,-32763;TAG1=-32763;TAG2=-32763,-32763 1 32764 . C A . . TAGV1=-32764;TAGV2=-32764,-32764;TAG1=-32764;TAG2=-32764,-32764 1 32765 . C A . . TAGV1=-32765;TAGV2=-32765,-32765;TAG1=-32765;TAG2=-32765,-32765 1 32766 . C A . . TAGV1=-32766;TAGV2=-32766,-32766;TAG1=-32766;TAG2=-32766,-32766 1 32767 . C A . . TAGV1=-32767;TAGV2=-32767,-32767;TAG1=-32767;TAG2=-32767,-32767 1 32768 . C A . . TAGV1=-32768;TAGV2=-32768,-32768;TAG1=-32768;TAG2=-32768,-32768 1 32769 . C A . . TAGV1=-32769;TAGV2=-32769,-32769;TAG1=-32769;TAG2=-32769,-32769 bcftools-1.21/test/query.nucleotide.vcf000066400000000000000000000531741467060157400202520ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##fileDate=20151104 ##source=dbSNP ##dbSNP_BUILD_ID=146 ##reference=GRCh37.p13 ##phasing=partial ##variationPropertyDocumentationUrl=ftp://ftp.ncbi.nlm.nih.gov/snp/specs/dbSNP_BitField_latest.pdf ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO=SubSNP->Batch.link_out"> ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO=5% minor allele frequency in each and all populations"> ##INFO=5% minor allele frequency in 1+ populations"> ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##INFO= ##INFO== 1% and for which 2 or more founders contribute to that minor allele frequency."> ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##bcftools_normVersion=1.6-33-g38e854b-dirty+htslib-1.6 ##bcftools_normCommand=norm --multiallelics -any --output /home/nicola/Downloads/dbSNP_All_20151104_split.vcf /home/nicola/Downloads/All_20151104.vcf.gz; Date=Fri Nov 24 13:40:52 2017 #CHROM POS ID REF ALT QUAL FILTER INFO 1 10019 rs775809821 TA T . . RS=775809821;RSPOS=10020;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10055 rs768019142 T TA . . RS=768019142;RSPOS=10055;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10108 rs62651026 C T . . RS=62651026;RSPOS=10108;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10109 rs376007522 A T . . RS=376007522;RSPOS=10109;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10128 rs796688738 A AC . . RS=796688738;RSPOS=10128;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10139 rs368469931 A T . . RS=368469931;RSPOS=10139;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10144 rs144773400 TA T . . RS=144773400;RSPOS=10145;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10146 rs779258992 AC A . . RS=779258992;RSPOS=10147;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10150 rs371194064 C T . . RS=371194064;RSPOS=10150;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10165 rs796884232 A AC . . RS=796884232;RSPOS=10165;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10177 rs201752861 A C . . RS=201752861;RSPOS=10177;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10177 rs367896724 A AC . . RS=367896724;RSPOS=10177;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005170026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;G5A;G5;KGPhase3;CAF=0.5747,0.4253;COMMON=1 1 10180 rs201694901 T C . . RS=201694901;RSPOS=10180;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10228 rs143255646 TA T . . RS=143255646;RSPOS=10229;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10228 rs200462216 TAACCCCTAACCCTAACCCTAAACCCTA T . . RS=200462216;RSPOS=10229;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10230 rs775928745 AC A . . RS=775928745;RSPOS=10231;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10231 rs200279319 C A . . RS=200279319;RSPOS=10231;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10234 rs145599635 C T . . RS=145599635;RSPOS=10234;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10235 rs540431307 T TA . . RS=540431307;RSPOS=10235;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;KGPhase3;CAF=0.9988,0.001198;COMMON=0 1 10247 rs796996180 T C . . RS=796996180;RSPOS=10247;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10248 rs148908337 A T . . RS=148908337;RSPOS=10248;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10249 rs774211241 AAC A . . RS=774211241;RSPOS=10250;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10250 rs199706086 A C . . RS=199706086;RSPOS=10250;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10254 rs140194106 TA T . . RS=140194106;RSPOS=10255;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10257 rs111200574 A C . . RS=111200574;RSPOS=10257;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050100020005000102000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;SLO;R5;ASP;GNO 1 10259 rs200940095 C A . . RS=200940095;RSPOS=10259;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10291 rs145427775 C T . . RS=145427775;RSPOS=10291;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10327 rs112750067 T C . . RS=112750067;RSPOS=10327;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10328 rs201106462 AACCCCTAACCCTAACCCTAACCCT A . . RS=201106462;RSPOS=10329;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10329 rs150969722 AC A . . RS=150969722;RSPOS=10330;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10352 rs555500075 N TA . . RS=555500075;RSPOS=10352;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005170026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;G5A;G5;KGPhase3;CAF=0.5625,0.4375;COMMON=1 1 10352 rs145072688 T TA . . RS=145072688;RSPOS=10353;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;CAF=0.5625,0.4375;COMMON=1 1 10383 rs147093981 A AC . . RS=147093981;RSPOS=10383;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10389 rs766767872 AC A . . RS=766767872;RSPOS=10390;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10433 rs56289060 A AC . . RS=56289060;RSPOS=10433;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10439 rs112766696 AC A . . RS=112766696;RSPOS=10440;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050100020005000102000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;SLO;R5;ASP;GNO 1 10440 rs112155239 C A . . RS=112155239;RSPOS=10440;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10458 rs796546892 A AC . . RS=796546892;RSPOS=10458;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10469 rs370233998 C G . . RS=370233998;RSPOS=10469;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10478 rs528916756 C G . . RS=528916756;RSPOS=10478;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10483 rs547662686 C T . . RS=547662686;RSPOS=10483;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10490 rs565971701 G A . . RS=565971701;RSPOS=10490;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10492 rs55998931 C T . . RS=55998931;RSPOS=10492;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10493 rs199606420 C A . . RS=199606420;RSPOS=10493;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10493 rs199606420 C G . . RS=199606420;RSPOS=10493;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10505 rs548419688 A T . . RS=548419688;RSPOS=10505;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10506 rs568405545 C G . . RS=568405545;RSPOS=10506;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10511 rs534229142 G A . . RS=534229142;RSPOS=10511;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10519 rs62636508 G C . . RS=62636508;RSPOS=10519;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10539 rs537182016 C A . . RS=537182016;RSPOS=10539;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040026000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.9994,0.000599;COMMON=0 1 10542 rs572818783 C T . . RS=572818783;RSPOS=10542;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10579 rs538322974 C A . . RS=538322974;RSPOS=10579;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10583 rs58108140 G A . . RS=58108140;RSPOS=10583;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000016000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase1 1 10603 rs200782791 G A . . RS=200782791;RSPOS=10603;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10611 rs189107123 C G . . RS=189107123;RSPOS=10611;dbSNPBuildID=135;SSR=0;SAO=0;VP=0x050000020005000014000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase1 1 10616 rs376342519 CCGCCGTTGCAAAGGCGCGCCG C . . RS=376342519;RSPOS=10617;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;KGPhase3;CAF=0.006989,0.993;COMMON=1 1 10642 rs558604819 G A . . RS=558604819;RSPOS=10642;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.9958,0.004193;COMMON=1 1 10828 rs10218492 G A . . RS=10218492;RSPOS=10828;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10904 rs10218493 G A . . RS=10218493;RSPOS=10904;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000102000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;GNO 1 10927 rs10218527 A G . . RS=10218527;RSPOS=10927;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10938 rs28853987 G A . . RS=28853987;RSPOS=10938;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 11008 rs575272151 C G . . RS=575272151;RSPOS=11008;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005150024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;G5;KGPhase3;CAF=0.9119,0.08806;COMMON=1 1 11012 rs544419019 C G . . RS=544419019;RSPOS=11012;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005150024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;G5;KGPhase3;CAF=0.9119,0.08806;COMMON=1 1 11014 rs28484712 G A . . RS=28484712;RSPOS=11014;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 11022 rs28775022 G A . . RS=28775022;RSPOS=11022;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 11063 rs561109771 T G . . RS=561109771;RSPOS=11063;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.997,0.002995;COMMON=1 1 22222 . AGTTCAGGGCCTGGAGAGAAGGCTGGGAGGCAGGAGCTGGGTCTAAAGAGGCCATTGTAACGATGGAGCTGTGCCTGTGGAGGCTGTTGTGAGGCAGTAGCCTCATCTGCGGAGGCTGCCGTGACATAGGGTATGGGCCTAAATAGGCCATTGTGAGTCATGAGCTTGGTCTGTAGAGGCTGACTGGAGAAAGTTCTGGGCCTGGAGAGGCTGCCGGGAGGTAGGAGCTGGGCCAAAAGATGTAAGCACATTTGCATTTATTAGGCACTTTATTTCCATTATTACACTGTAATATATAATAAAATAATTATAGAACTCACCATAATGTAGAATTAGTGGGCGTGTTAAGCTTGTTTTCCTGCAACTGAATGGTCCCACCTGAGCGTGATGGGAGAAAGTGACAGATCAATAGGTATTAGATTCTCATAAGGACAGCGCAACCTCGATCCCTCACATGCACGGTTCACAACAGGGTGCGTTCTCCTATGAGCATCTAATGCTGCTGCTCATCTGAGAAGGTGGAGCTCAGGTGGGAATGTGAGCAAAGGGGAGTGGCTCTAAATACAGACGAAGCTTCCCTCACTCCCTCACTCGACACCGCTCACCTCCTGCTGTGTGGCTCCTTGCGGCTCCATGGCTCAGGGGTTGGGGACCCCTGCTCAAGTGCATCCAAAGCGACCCTTCCCACACCAGTCTTCACAGTGGTCAAGGGCAGCAACCACTTAGCTCCCAAGGCATGTGCCTCAGCTGGCATTTCGTCACAATCAACAGTAAGTGGTAGCTTGAGTCACTGTGAGGTCACCTACTGGAAATCACCAGCACCCCATTTCCCACTGGCAAAGAGCTCAGCACTGCCCCCTGGGAAACCAAACCTATGCCCAAATCCCATCTGTGTGGGTCTACCTCCTGGGACCCTTCCTAACATATTAGTCAGAGTCCAATCAGGAAGCATAAACCACTCAAAAGTTTAAAGTGGTAAAATTTAATACAGAGAATTATTCATTATAACAGGTGAACAGCATAATGAGAGATTGGCTAGCACAGAGTAAAGAGAACTCTAGAGAATATGGGACTAGCCCAGGCCAGGCATGGTGGCTCATGCCTGAAATTCCAGCCATTACAGAAGCTAATGCAGGAGGATTGCTTAAGGCCAGGAGCTAGAGACCGGTCTGGACGACACAGTGAGACCCTGTCTCTATCCAAAAGAAGAAAAAAGTTAGCTGGGGGTGGTGGTGCACACTTGTAGTCCCAGCTACTCAGAATGCTGAAGTTTGAGCCTGGGAGGTCAAGGCTGCAGTGAGGCATGATTATGCCACTACAGTCCAGCCGGATGACAGAGCAAGACCCTGTCTCAAAGAACAAAACCACAACAACCATTTACAGACAGAAAAGAAATAGAGCTAATAAGCTGAGGAAAGATGTTGAAATGTGACAAGTAAAGTAATATGAGGTCTTTTGTCTATTTAAAATAATCAAACAAAAAATGGCTTACGAAATTATAATACCCTGTGCTGGCAAAGGTGCAGTGAAATGGGCACTTTCTTATACTATGAGGGGTGGTTAAATTGTGTATAAGCCTTCCAGGGTAAAGCCTGTCAATTTTTTAAAATAATGGAGACAGGGTCTCACCATACTGCCATACTGCCTCCTCCAACTCTTGGCCTCAAGCAATCCTCCTCTCTTAGCCTCCCAAAGTGCTAAGATTATAGCTGGGAGGCACCCAAAACCCTGTCAATTTACATCAAGGGTAAGGAGAATGTCCATTCACCATGACTCACAGTAATCTTACTTCTGGGGAGACAATTCAATCTAAGCAAAAGGTCATCTGTACACACACAGTAAAAATCTGGGAGTAACTGAAGACAGAGTTGGTAAGTGAAATAAGAAACAGTTATAAGAAATTAAACTATGGTATCAATAGGCACCTGGTAAAAGGTCAGTTGATGTTAGCTGCTACTTTTTTGTTGTTTTGAGACAGGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGAGGCCTGATCATGACTCACTGCAGTCTCAGCCTCCCTGGGCTCAAGTGATCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGGAACATGCCACCACACTAGGCTAATTCATGTATTTTTCTGTAGGGATGGTGACTCCCCCTTTGTTTCCAAGGCCTATCGCAAACTCTTGGCCTCGAGCCATCCTCCTGCCTCAGCCTCCCAAAGTGTTGTGATTACCAGTGTGAGCCACCACACCTGGCCAGCTGCTACTTTTATCAATATTATTCTTATTCCACTCAATTAAAAATTATTATTTTCAAGGCTATGCAACAGTATGTATCCTACAGCGTAATTGTAAAAACATACACAGTCGTCATCCCTCAGTATACAGAATTAGTTCCAGCCCCCCATCTCTGCATATACCAAAATCCATGCTTACTCACGTTTCGCTGTCACCCCTCTAGAATCCACGTATACGAAAATTCCAAATGTTAGTTGGGCATAGTGGCAAGCACCTGTAGTCTCAGCCACGTGGGAGGTTGAGGTGGGAGGATCGCTTCAGCCTGGAAGGTTGAGGCTGCAGTCAGCTGCGATAGCACTACTACACTCCAGCCTTGGACAACAGAGGGAGACCCTGTCTCAGAAAAAAAAACAAAATAAAACAGGTTAGAAATTGTAATGAGGTCTGCTGGGCAAAATTCCATATAAGCAATGTATAAATTAATAAAGCAAATCGTGATAAATTAGTACGATTGACTTTCTGGAGTTTCTGACAATAAAAGTAAGGAAAATGCAGAACACAAAGACAGAGAGTAAAAAGAGAAATTAGGAAAGCATTCTACATGTTGAATAGGAAGACACTGGCCATGTTCGTGCAGCGGCAGTATGTCGTGACATGACATACCTTGGAGAGAAGTTAACAGATGAGGAAGTTGATAAAAATCATCAGAGAAGCAAAATACTGGTAGCGACACTCAAGTAAACCATGAAATTTCCATAACTTATGTCAGCAAAGTGGGAATATTGTACAGTGTGTGTTGAAGTTCCTATACAACATTGTTTATCTGCCTTTTGTTTGTTTGTAAGGAATGTACATACTAAAAGTTCTTCTTGCTGTCAAAAGAATATGCGTGAATAAGTCATTTTAACTTATTCTTCTGTTTTTCTTTTATCTTCCTGCCATCATCCCACAGCCTTACTTTAGAAATTTCTTTTTTAGAAAATTGAACAAGTGCTCCCTGTGGTGGCACATACCTCGAGGATGGGAGGCAGGGGTGGAAGGGTCACTTGAGGCCATTAGTTTGACACCAGCCTGGCCAACAAAGTGAGACCCCGTGTCTACAAAACAATTTAAAAATTAGCCAAGTATCGTCATGTATACCTACAGTCCCAGCTATCTGAACTTACTGAGAAT A . . . bcftools-1.21/test/query.out000066400000000000000000000010301467060157400161310ustar00rootroot000000000000001 3062915 GTTT G 1,2,3,4 4 0/1 GTTT/G 0/1 GTTT/G 1 3062915 G C,T 1,2,3,4 4 0/1 G/C 0/2 G/T 1 3062915 GTT G 1,2,3,4 4 0/1 GTT/G 0/1 GTT/G 1 3106154 CAAA C . 0 . . ./. ./. 1 3106154 C CT . 4 0/1 C/CT 0/1 C/CT 1 3157410 G T . 4 1/1 T/T 1/1 T/T 1 3162006 GAA G . 4 0/1 GAA/G 0/1 GAA/G 1 3177144 G . . 4 0/0 G/G 0/0 G/G 1 3184885 TAAAA TA,T . 4 1/2 TA/T 1/2 TA/T 2 3199812 G GTT,GT . 4 1/2 GTT/GT 1/2 GTT/GT 3 3212016 CTT C,CT . 4 1/2 C/CT 1/2 C/CT 4 3258448 TACACACAC T . 4 0/1 TACACACAC/T 0/1 TACACACAC/T 4 3258449 A C . 4 1/1 C/C 0/1 A/C bcftools-1.21/test/query.pbinom.1.vcf000066400000000000000000000022341467060157400175310ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FORMAT= ##FORMAT= ##INFO= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 150 . C T,A 59.2 PASS AD=0,0,0 GT:AD ./.:0,0,0 ./.:0,0,0 1 151 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:1,1,0 0/0:0,0,0 1 152 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,1,0 0/0:0,0,0 1 153 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,2,0 0/0:0,0,0 1 154 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,3,0 0/0:0,0,0 1 155 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,4,0 0/0:0,0,0 1 156 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,5,0 0/0:0,0,0 1 157 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,6,0 0/0:0,0,0 1 158 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,7,0 0/0:0,0,0 1 159 . C T,A 59.2 PASS AD=0,0,0 GT:AD 0/1:0,8,0 0/0:0,0,0 1 160 . C T,A 59.2 PASS AD=0,0,0 GT:AD 1/2:0,9,0 0/0:0,0,0 1 161 . C T,A 59.2 PASS AD=0,0,0 GT:AD 1/2:0,119,0 0/0:1,0,0 bcftools-1.21/test/query.smpl.1.out000066400000000000000000000000071467060157400172450ustar00rootroot0000000000000011 1/1 bcftools-1.21/test/query.smpl.11.txt000066400000000000000000000000031467060157400173320ustar00rootroot0000000000000011 bcftools-1.21/test/query.smpl.2.out000066400000000000000000000000031467060157400172420ustar00rootroot0000000000000011 bcftools-1.21/test/query.smpl.3.out000066400000000000000000000000071467060157400172470ustar00rootroot0000000000000000 0/0 bcftools-1.21/test/query.smpl.4.out000066400000000000000000000000031467060157400172440ustar00rootroot0000000000000000 bcftools-1.21/test/query.smpl.5.out000066400000000000000000000000161467060157400172510ustar00rootroot0000000000000011 1/1 00 0/0 bcftools-1.21/test/query.smpl.6.out000066400000000000000000000000061467060157400172510ustar00rootroot0000000000000000 11 bcftools-1.21/test/query.smpl.txt000066400000000000000000000000061467060157400171150ustar00rootroot0000000000000011 00 bcftools-1.21/test/query.smpl.vcf000066400000000000000000000002731467060157400170620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 00 11 chr1 10000 . A C . . . GT 0/0 1/1 bcftools-1.21/test/query.string.1.out000066400000000000000000000002431467060157400176020ustar00rootroot000000000000001 865568 criteria_provided,_conflicting_interpretations 1 865628 criteria_provided,_multiple_submitters,_no_conflicts 1 865716 criteria_provided,_single_submitter bcftools-1.21/test/query.string.2.1.out000066400000000000000000000000361467060157400177420ustar00rootroot000000000000001 865568 AA,BB 1 865628 BB,CC bcftools-1.21/test/query.string.2.1.txt000066400000000000000000000000031467060157400177440ustar00rootroot00000000000000BB bcftools-1.21/test/query.string.2.2.out000066400000000000000000000000211467060157400177350ustar00rootroot000000000000001 865568 P,Q Q,R bcftools-1.21/test/query.string.2.2.txt000066400000000000000000000000021467060157400177440ustar00rootroot00000000000000Q bcftools-1.21/test/query.string.2.out000066400000000000000000000000701467060157400176010ustar00rootroot000000000000001 865568 criteria_provided,_conflicting_interpretations bcftools-1.21/test/query.string.2.vcf000066400000000000000000000005601467060157400175540ustar00rootroot00000000000000##fileformat=VCFv4.3 ##reference=GRCh37 ##contig= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 1 865568 . G A . . STR=AA,BB STR P,Q Q,R 1 865628 . G A . . STR=BB,CC STR R,S S,T 1 865716 . G A . . STR=CC,DD STR T,U U,V bcftools-1.21/test/query.string.vcf000066400000000000000000000007051467060157400174150ustar00rootroot00000000000000##fileformat=VCFv4.3 ##reference=GRCh37 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 865568 . G A . . CLNREVSTAT=criteria_provided,_conflicting_interpretations 1 865628 . G A . . CLNREVSTAT=criteria_provided,_multiple_submitters,_no_conflicts 1 865716 . G A . . CLNREVSTAT=criteria_provided,_single_submitter bcftools-1.21/test/query.variantkey.hex.out000066400000000000000000000032641467060157400211030ustar00rootroot000000000000002e3deb1d 0800139110e60000 2dc70ac6 080013a309780000 03bbfa92 080013bd88b80000 16696b62 080013be08980000 2f7c8162 080013c789020000 15f667ab 080013cd08980000 08a11118 080013cf90e60000 2e728c70 080013d090880000 161ff8d0 080013d288b80000 2f7f7d08 080013da09020000 0c06811d 080013e008880000 15eda894 080013e009020000 0c059eb5 080013e188e80000 0889e85e 080013f990e60000 0bf2cf88 080013f9a00e1d03 2e3fbba9 080013fa90880000 0bf00517 080013fb08a00000 08adac93 080013fc88b80000 203653cb 080013fd09780000 2f813254 0800140308e80000 08e02931 0800140388980000 2e2586a9 0800140418820000 0be745e6 0800140488880000 085b313a 0800140690e60000 06a0c93e 0800140808880000 0bfa1a3f 0800140908a00000 08ab0d3f 0800141908b80000 06b86df3 0800142b08e80000 0bfca41e 0800142b90367897 08ff9d7a 0800142c10880000 211c422b 0800143789780000 08a5a230 0800143789780000 08c479dd 0800144709020000 2db3f300 0800144a10880000 035ae724 0800146009020000 06b8aee8 0800146310880000 06af5a67 0800146388a00000 2f7a574c 0800146c89020000 1611528e 0800147208b00000 1f86a114 0800147688b00000 20a4ab5e 0800147908b80000 21bc0af5 0800147c88c00000 035679d3 0800147d88b80000 0be5c094 0800147e08a00000 0be5c094 0800147e08b00000 20b03868 0800148408980000 21e12e29 0800148488b00000 1fd7b096 0800148708c00000 03bbc1dc 0800148b08c80000 2004bf40 0800149508a00000 2224855f 0800149688b80000 2016281e 080014a908a00000 0376a8ec 080014ab08c00000 0bf7b3c7 080014b508c00000 0b458bb3 080014b908b00000 166e87f7 080014bb8ad3d64f 214ba213 080014c888c00000 009bebfc 0800152588c00000 009bebfd 0800154b88c00000 009bec1f 0800155708900000 01b846e3 0800155c88c00000 2249f4d7 0800157f88b00000 20732ccb 0800158188b00000 01b2a468 0800158288c00000 01b7126e 0800158688c00000 2171db0b 0800159b08f00000 bcftools-1.21/test/query.variantkey.vcf000066400000000000000000000444271467060157400202750ustar00rootroot00000000000000##fileformat=VCFv4.0 ##FILTER= ##fileDate=20151104 ##source=dbSNP ##dbSNP_BUILD_ID=146 ##reference=GRCh37.p13 ##phasing=partial ##variationPropertyDocumentationUrl=ftp://ftp.ncbi.nlm.nih.gov/snp/specs/dbSNP_BitField_latest.pdf ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO=SubSNP->Batch.link_out"> ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO=5% minor allele frequency in each and all populations"> ##INFO=5% minor allele frequency in 1+ populations"> ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##INFO= ##INFO== 1% and for which 2 or more founders contribute to that minor allele frequency."> ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##bcftools_normVersion=1.6-33-g38e854b-dirty+htslib-1.6 ##bcftools_normCommand=norm --multiallelics -any --output /home/nicola/Downloads/dbSNP_All_20151104_split.vcf /home/nicola/Downloads/All_20151104.vcf.gz; Date=Fri Nov 24 13:40:52 2017 #CHROM POS ID REF ALT QUAL FILTER INFO 1 10019 rs775809821 TA T . . RS=775809821;RSPOS=10020;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10055 rs768019142 T TA . . RS=768019142;RSPOS=10055;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10108 rs62651026 C T . . RS=62651026;RSPOS=10108;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10109 rs376007522 A T . . RS=376007522;RSPOS=10109;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10128 rs796688738 A AC . . RS=796688738;RSPOS=10128;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10139 rs368469931 A T . . RS=368469931;RSPOS=10139;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10144 rs144773400 TA T . . RS=144773400;RSPOS=10145;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10146 rs779258992 AC A . . RS=779258992;RSPOS=10147;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10150 rs371194064 C T . . RS=371194064;RSPOS=10150;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10165 rs796884232 A AC . . RS=796884232;RSPOS=10165;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10177 rs201752861 A C . . RS=201752861;RSPOS=10177;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10177 rs367896724 A AC . . RS=367896724;RSPOS=10177;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005170026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;G5A;G5;KGPhase3;CAF=0.5747,0.4253;COMMON=1 1 10180 rs201694901 T C . . RS=201694901;RSPOS=10180;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10228 rs143255646 TA T . . RS=143255646;RSPOS=10229;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10228 rs200462216 TAACCCCTAACCCTAACCCTAAACCCTA T . . RS=200462216;RSPOS=10229;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10230 rs775928745 AC A . . RS=775928745;RSPOS=10231;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10231 rs200279319 C A . . RS=200279319;RSPOS=10231;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10234 rs145599635 C T . . RS=145599635;RSPOS=10234;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10235 rs540431307 T TA . . RS=540431307;RSPOS=10235;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;KGPhase3;CAF=0.9988,0.001198;COMMON=0 1 10247 rs796996180 T C . . RS=796996180;RSPOS=10247;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10248 rs148908337 A T . . RS=148908337;RSPOS=10248;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10249 rs774211241 AAC A . . RS=774211241;RSPOS=10250;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10250 rs199706086 A C . . RS=199706086;RSPOS=10250;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10254 rs140194106 TA T . . RS=140194106;RSPOS=10255;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10257 rs111200574 A C . . RS=111200574;RSPOS=10257;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050100020005000102000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;SLO;R5;ASP;GNO 1 10259 rs200940095 C A . . RS=200940095;RSPOS=10259;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10291 rs145427775 C T . . RS=145427775;RSPOS=10291;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10327 rs112750067 T C . . RS=112750067;RSPOS=10327;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10328 rs201106462 AACCCCTAACCCTAACCCTAACCCT A . . RS=201106462;RSPOS=10329;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10329 rs150969722 AC A . . RS=150969722;RSPOS=10330;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10352 rs555500075 T TA . . RS=555500075;RSPOS=10352;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005170026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;G5A;G5;KGPhase3;CAF=0.5625,0.4375;COMMON=1 1 10352 rs145072688 T TA . . RS=145072688;RSPOS=10353;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;CAF=0.5625,0.4375;COMMON=1 1 10383 rs147093981 A AC . . RS=147093981;RSPOS=10383;dbSNPBuildID=134;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10389 rs766767872 AC A . . RS=766767872;RSPOS=10390;dbSNPBuildID=144;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10433 rs56289060 A AC . . RS=56289060;RSPOS=10433;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10439 rs112766696 AC A . . RS=112766696;RSPOS=10440;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050100020005000102000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;SLO;R5;ASP;GNO 1 10440 rs112155239 C A . . RS=112155239;RSPOS=10440;dbSNPBuildID=132;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10458 rs796546892 A AC . . RS=796546892;RSPOS=10458;dbSNPBuildID=146;SSR=0;SAO=0;VP=0x050000020005000002000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP 1 10469 rs370233998 C G . . RS=370233998;RSPOS=10469;dbSNPBuildID=138;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10478 rs528916756 C G . . RS=528916756;RSPOS=10478;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10483 rs547662686 C T . . RS=547662686;RSPOS=10483;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10490 rs565971701 G A . . RS=565971701;RSPOS=10490;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10492 rs55998931 C T . . RS=55998931;RSPOS=10492;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10493 rs199606420 C A . . RS=199606420;RSPOS=10493;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10493 rs199606420 C G . . RS=199606420;RSPOS=10493;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10505 rs548419688 A T . . RS=548419688;RSPOS=10505;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10506 rs568405545 C G . . RS=568405545;RSPOS=10506;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10511 rs534229142 G A . . RS=534229142;RSPOS=10511;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10519 rs62636508 G C . . RS=62636508;RSPOS=10519;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10539 rs537182016 C A . . RS=537182016;RSPOS=10539;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040026000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.9994,0.000599;COMMON=0 1 10542 rs572818783 C T . . RS=572818783;RSPOS=10542;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10579 rs538322974 C A . . RS=538322974;RSPOS=10579;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005000024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase3;CAF=0.9998,0.0001997;COMMON=0 1 10583 rs58108140 G A . . RS=58108140;RSPOS=10583;dbSNPBuildID=129;SSR=0;SAO=0;VP=0x050000020005000016000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase1 1 10603 rs200782791 G A . . RS=200782791;RSPOS=10603;dbSNPBuildID=137;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10611 rs189107123 C G . . RS=189107123;RSPOS=10611;dbSNPBuildID=135;SSR=0;SAO=0;VP=0x050000020005000014000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;KGPhase1 1 10616 rs376342519 CCGCCGTTGCAAAGGCGCGCCG C . . RS=376342519;RSPOS=10617;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040026000200;GENEINFO=DDX11L1:100287102;WGT=1;VC=DIV;R5;ASP;VLD;KGPhase3;CAF=0.006989,0.993;COMMON=1 1 10642 rs558604819 G A . . RS=558604819;RSPOS=10642;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.9958,0.004193;COMMON=1 1 10828 rs10218492 G A . . RS=10218492;RSPOS=10828;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10904 rs10218493 G A . . RS=10218493;RSPOS=10904;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000102000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;GNO 1 10927 rs10218527 A G . . RS=10218527;RSPOS=10927;dbSNPBuildID=119;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 10938 rs28853987 G A . . RS=28853987;RSPOS=10938;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 11008 rs575272151 C G . . RS=575272151;RSPOS=11008;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005150024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;G5;KGPhase3;CAF=0.9119,0.08806;COMMON=1 1 11012 rs544419019 C G . . RS=544419019;RSPOS=11012;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005150024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;G5;KGPhase3;CAF=0.9119,0.08806;COMMON=1 1 11014 rs28484712 G A . . RS=28484712;RSPOS=11014;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 11022 rs28775022 G A . . RS=28775022;RSPOS=11022;dbSNPBuildID=125;SSR=0;SAO=0;VP=0x050000020005000002000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP 1 11063 rs561109771 T G . . RS=561109771;RSPOS=11063;dbSNPBuildID=142;SSR=0;SAO=0;VP=0x050000020005040024000100;GENEINFO=DDX11L1:100287102;WGT=1;VC=SNV;R5;ASP;VLD;KGPhase3;CAF=0.997,0.002995;COMMON=1 bcftools-1.21/test/query.vcf000066400000000000000000000044101467060157400161050ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D 1 3062915 id3D GTTT G 48.7 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 1 3062915 idSNP G C,T 419 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:109:35:-10,-5,-20,-20,-5,-20 1 3062915 id2D GTT G 999 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 1 3106154 . CAAA C 72.6 PASS AN=0;AC=0 GT:GQ:DP .:245:32 ./.:145:22 1 3106154 . C CT 459 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:145:22 1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:11:11 1 3162006 . GAA G 206 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:112:12 1 3177144 . G . 364 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:20 1 3184885 . TAAAA TA,T 8.42 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:22:20 1/2:12:10 2 3199812 . G GTT,GT 291 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:122:16 3 3212016 . CTT C,CT 52.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:11:16 4 3258448 . TACACACAC T 123 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:125:11 4 3258449 . A C 123 PASS AN=4;AC=3 GT:GQ:DP 1/1:325:31 0/1:125:11 bcftools-1.21/test/ref.out000066400000000000000000000021651467060157400155520ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 105 . TAAACCCTA T,TAACCCTA 999 PASS . 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . 2 101 . A ATT 999 PASS . 2 114 . T TTC,TT 999 PASS . 2 115 . C T 999 PASS . 20 3 . G CT 999 PASS . 20 5 . TG CT 999 PASS . 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . 20 59 . AG . 999 PASS . 20 81 . A C 999 PASS . 20 84 . G T 999 PASS . 20 95 . T A 999 PASS . 20 95 . TCACCG AAAAAA 999 PASS . 20 273 . C CAA,CAAA 999 PASS . 20 273 . C CAAAAAAAAAA 999 PASS . 20 273 . C CAA 999 PASS . 20 275 . A C,G 999 PASS . 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . 3 17 . CA C 999 PASS . 4 36 . TC C,TT,TTC 999 PASS . 5 21 . A AAG 999 PASS . bcftools-1.21/test/ref.vcf000066400000000000000000000021651467060157400155210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 105 . TAAACCCTA T,TAACCCTA 999 PASS . 2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . 2 101 . N ATT 999 PASS . 2 114 . N TTC,TT 999 PASS . 2 115 . N T 999 PASS . 20 3 . N CT 999 PASS . 20 5 . NN CT 999 PASS . 20 5 . TGGG TAC,TG,TGGGG,AC . PASS . 20 59 . NN . 999 PASS . 20 81 . N C 999 PASS . 20 84 . N T 999 PASS . 20 95 . N A 999 PASS . 20 95 . TCACCG AAAAAA 999 PASS . 20 273 . N CAA,CAAA 999 PASS . 20 273 . N CAAAAAAAAAA 999 PASS . 20 273 . N CAA 999 PASS . 20 275 . N C,G 999 PASS . 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . 3 17 . CA C 999 PASS . 4 36 . TC C,TT,TTC 999 PASS . 5 21 . A AAG 999 PASS . bcftools-1.21/test/regions.out000066400000000000000000000002231467060157400164350ustar00rootroot000000000000001 3062915 GTT,G 1 3062915 G,T 1 3106154 CA,C 1 3106154 C,T,CT 1 3157410 G,A 1 3162006 G,A 1 3184885 T,TA 2 3199815 C,T 3 3212016 C,A 3 3212036 C,A bcftools-1.21/test/regions.tab000066400000000000000000000002201467060157400163710ustar00rootroot000000000000001 3062915 3062915 1 3106154 3106154 1 3157410 3157410 1 3162006 3162006 1 3184885 3184885 2 3199815 3199815 3 3212016 3212016 3 3212036 3212036 bcftools-1.21/test/regions.vcf000066400000000000000000000034271467060157400164150ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##test= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3062915 . GTT G 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 3062915 . G T 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 1 3106154 . CA C 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 1 3106154 . C T,CT 1792 PASS DP=32;AN=2;AC=1,0 GT:GQ:DP 0/1:245:32 1 3157410 . G A 628 q10 DP=21;AN=2;AC=2 GT:GQ:DP 1/1:21:21 1 3162006 . G A 1016 PASS DP=22;AN=2;AC=1 GT:GQ:DP 0/1:212:22 1 3177144 . GT G 727 PASS DP=30;AN=2;AC=1 GT:GQ:DP 0/1:150:30 1 3184885 . T TA 246 PASS DP=10;AN=2;AC=1 GT:GQ:DP 1/2:12:10 2 3199812 . G T 481 PASS DP=26;AN=2;AC=1 GT:GQ:DP 1/2:322:26 2 3199815 . C T 481 PASS DP=26;AN=2;AC=1 GT:GQ:DP 1/2:322:26 3 3212016 . C A 565 PASS DP=26;AN=2;AC=1 GT:GQ:DP 1/2:91:26 3 3212026 . C A 565 PASS DP=26;AN=2;AC=1 GT:GQ:DP 1/2:91:26 3 3212036 . C A 565 PASS DP=26;AN=2;AC=1 GT:GQ:DP 1/2:91:26 bcftools-1.21/test/reheader.1.out000066400000000000000000000050331467060157400167110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##FILTER= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA0001 BBB0002 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.1.out.bcf000066400000000000000000000050331467060157400174420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##FILTER= ##INFO= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA0001 BBB0002 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.2.hdr000066400000000000000000000053371467060157400166670ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##FORMAT= ##contig=> \"sapiens\" sapiens",ID=4> ##contig=> \"\"sapiens\"\" sapiens",length=2147483647> ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 bcftools-1.21/test/reheader.2.out000066400000000000000000000075711467060157400167230ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA BBB 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.2.vcf000066400000000000000000000102421467060157400166570ustar00rootroot00000000000000##fileformat=VCFv4.1 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##FORMAT= ##contig=> \"sapiens\" sapiens",ID=4> ##contig=> \"\"sapiens\"\" sapiens",length=2147483647> ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.3.fai000066400000000000000000000010501467060157400166360ustar00rootroot000000000000001 2364278061 6 2364278061 2364278062 2 2317450362 7159592787 2317450362 2317450363 3 2291775479 9477043156 2291775479 2291775480 4 2192534405 11768818642 2192534405 2192534406 5 2148190925 13961353054 2148190925 2148190926 6 2107674557 16109543986 2107674557 2107674558 7 2082167746 18217218550 2082167746 2082167747 8 2081484518 20299386303 2081484518 2081484519 9 2024734096 22380870828 2024734096 2024734097 10 1752849333 2364278075 1752849333 1752849334 11 1650012615 4117127416 1650012615 1650012616 12 1392452741 5767140039 1392452741 1392452742 bcftools-1.21/test/reheader.3.out000066400000000000000000000075731467060157400167260ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A AA BB B 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.3.vcf000066400000000000000000000001461467060157400166620ustar00rootroot00000000000000##fileformat=VCFv4.3 ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 22 . A G . . . bcftools-1.21/test/reheader.4.out000066400000000000000000000075741467060157400167300ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 BB 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.5.out000066400000000000000000000114141467060157400167150ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##contig= ##contig= ##contig= ##FORMAT= ##contig=> \"sapiens\" sapiens"> ##contig=> \"\"sapiens\"\" sapiens"> ##contig= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/reheader.6.out000066400000000000000000000010341467060157400167130ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 22 . 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ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 bcftools-1.21/test/remove-overlaps.1.1.out000066400000000000000000000004321467060157400204150ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 789241 . C G . . . 1 789243 . C CA . . . 1 790000 . C G . . . 1 900000 . C G . . . bcftools-1.21/test/remove-overlaps.1.2.out000066400000000000000000000015161467060157400204220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 100000 . CC G . . overlap 1 100001 . C G . . overlap 1 789241 . C G . . . 1 789242 . C G . . overlap 1 789242 . C A . . overlap 1 789243 . C CA . . . 1 789243 . C CCA . . overlap 1 789244 . C A . . overlap 1 789244 . C CA . . overlap 1 789244 . C T . . overlap 1 789244 . C CCA . . overlap 1 789245 . C T,CA,TTT . . overlap 1 789245 . C T,A . . overlap 1 789245 . C T . . overlap 1 789245 . C A,T . . overlap 1 789245 . C T . . overlap 1 789245 . C CA,TTT,T . . overlap 1 790000 . C G . . . 1 800000 . CC G . . overlap 1 800001 . C G . . overlap 1 900000 . C G . . . bcftools-1.21/test/remove-overlaps.1.3.out000066400000000000000000000000441467060157400204160ustar00rootroot000000000000001 789241 1 789243 1 790000 1 900000 bcftools-1.21/test/remove-overlaps.1.4.out000066400000000000000000000011031467060157400204140ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 100000 . CC G . . . 1 100001 . C G . . . 1 789242 . C G . . . 1 789242 . C A . . . 1 789243 . C CCA . . . 1 789244 . C A . . . 1 789244 . C CA . . . 1 789244 . C T . . . 1 789244 . C CCA . . . 1 789245 . C T,CA,TTT . . . 1 789245 . C T,A . . . 1 789245 . C T . . . 1 789245 . C A,T . . . 1 789245 . C T . . . 1 789245 . C CA,TTT,T . . . 1 800000 . CC G . . . 1 800001 . C G . . . bcftools-1.21/test/remove-overlaps.1.5.out000066400000000000000000000014001467060157400204150ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 100000 . CC G . . . 1 100001 . C G . . . 1 789241 . C G . . . 1 789242 . C G . . DUP 1 789242 . C A . . DUP 1 789243 . C CA . . DUP 1 789243 . C CCA . . DUP 1 789244 . C A . . DUP 1 789244 . C CA . . DUP 1 789244 . C T . . DUP 1 789244 . C CCA . . DUP 1 789245 . C T,CA,TTT . . DUP 1 789245 . C T,A . . DUP 1 789245 . C T . . DUP 1 789245 . C A,T . . DUP 1 789245 . C T . . DUP 1 789245 . C CA,TTT,T . . DUP 1 790000 . C G . . . 1 800000 . CC G . . . 1 800001 . C G . . . 1 900000 . 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DP=114;rmme chr 398041 . G . . DP=114;rmme chr 398042 . A . . DP=114;rmme chr 398043 . G . . DP=114;rmme chr 398044 . C . . DP=114;rmme chr 398045 . G A, 209.77 . DP=89 chr 398046 . G . . DP=109;rmme chr 398047 . T . . DP=109;rmme chr 398048 . G . . DP=109;rmme chr 398049 . C . . DP=109;rmme chr 398050 . A . . DP=109;rmme chr 398051 . A . . DP=109;rmme chr 398052 . T . . DP=109;rmme chr 398053 . G . . DP=109;rmme chr 398054 . C . . DP=109;rmme chr 398055 . A . . DP=98;rmme bcftools-1.21/test/remove-overlaps.3.2.out000066400000000000000000000021621467060157400204220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr 398016 . T . . DP=74 chr 398017 . GGGGACCCTTCCCTGTGCCTGGCAGAGCGGTGCAATGCA G, 27.74 . DP=93;rmme chr 398036 . T C, 161.77 . DP=79 chr 398037 . G . . DP=114 chr 398038 . G . . DP=114 chr 398039 . C . . DP=114 chr 398040 . A . . DP=114 chr 398041 . G . . DP=114 chr 398042 . A . . DP=114 chr 398043 . G . . DP=114 chr 398044 . C . . DP=114 chr 398045 . G A, 209.77 . DP=89 chr 398046 . G . . DP=109 chr 398047 . T . . DP=109 chr 398048 . G . . DP=109 chr 398049 . C . . DP=109 chr 398050 . A . . DP=109 chr 398051 . A . . DP=109 chr 398052 . T . . DP=109 chr 398053 . G . . DP=109 chr 398054 . C . . DP=109 chr 398055 . A . . DP=98 bcftools-1.21/test/remove-overlaps.3.vcf000066400000000000000000000017541467060157400202370ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr 398016 . T . . DP=74 chr 398017 . GGGGACCCTTCCCTGTGCCTGGCAGAGCGGTGCAATGCA G, 27.74 . DP=93 chr 398036 . T C, 161.77 . DP=79 chr 398037 . G . . DP=114 chr 398038 . G . . DP=114 chr 398039 . C . . DP=114 chr 398040 . A . . DP=114 chr 398041 . G . . DP=114 chr 398042 . A . . DP=114 chr 398043 . G . . DP=114 chr 398044 . C . . DP=114 chr 398045 . G A, 209.77 . DP=89 chr 398046 . G . . DP=109 chr 398047 . T . . DP=109 chr 398048 . G . . DP=109 chr 398049 . C . . 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C A . . . GT 0/0 1/1 21 22 . A C . . . GT 1/1 0/0 21 23 . C A . . . GT 0/0 0/0 #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 21 24 . A C . . . GT 1/1 1/1 22 10 . C A . . . GT 0/1 0/0 22 22 . A C . . . GT 0/0 0/1 #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 22 23 . C A . . . GT 0/0 1/0 X 10 . A C . . . GT 0/1 0/1 X 22 . C A . . . GT 0/1 0/1 bcftools-1.21/test/scatter.1.2.out000066400000000000000000000004571467060157400167440ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 21 10 . C A . . . GT 0/0 1/1 21 22 . A C . . . GT 1/1 0/0 21 23 . C A . . . GT 0/0 0/0 21 24 . A C . . . GT 1/1 1/1 #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 22 10 . C A . . . GT 0/1 0/0 22 22 . A C . . . GT 0/0 0/1 22 23 . C A . . . GT 0/0 1/0 bcftools-1.21/test/scatter.1.3.out000066400000000000000000000006311467060157400167370ustar00rootroot00000000000000#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 21 10 . C A . . . GT 0/0 1/1 21 22 . A C . . . GT 1/1 0/0 21 23 . C A . . . GT 0/0 0/0 21 24 . A C . . . GT 1/1 1/1 #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 22 10 . C A . . . GT 0/1 0/0 22 22 . A C . . . GT 0/0 0/1 22 23 . C A . . . GT 0/0 1/0 #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B X 10 . A C . . . GT 0/1 0/1 X 22 . C A . . . GT 0/1 0/1 bcftools-1.21/test/scatter.1.vcf000066400000000000000000000010001467060157400165340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fasta ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 21 10 . C A . . . GT 0/0 1/1 21 22 . A C . . . GT 1/1 0/0 21 23 . C A . . . GT 0/0 0/0 21 24 . A C . . . GT 1/1 1/1 22 10 . C A . . . GT 0/1 0/0 22 22 . A C . . . GT 0/0 0/1 22 23 . C A . . . GT 0/0 1/0 X 10 . A C . . . GT 0/1 0/1 X 22 . C A . . . GT 0/1 0/1 bcftools-1.21/test/select-tr-expr.1.out000066400000000000000000000001221467060157400200020ustar00rootroot000000000000001789242 YES NM_002074.5 missense_variant 1804496 YES NM_002074.5 missense_variant bcftools-1.21/test/select-tr-expr.2.out000066400000000000000000000025101467060157400200060ustar00rootroot000000000000001000000 . . missense_variant 1529299 . . 3_prime_UTR_variant&NMD_transcript_variant 1789242 .,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. .,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. downstream_gene_variant,missense_variant,non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,synonymous_variant&NMD_transcript_variant,missense_variant,missense_variant,upstream_gene_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,regulatory_region_variant,regulatory_region_variant 1804496 .,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. .,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. missense_variant,downstream_gene_variant,missense_variant,non_coding_transcript_exon_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant&NMD_transcript_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant,missense_variant bcftools-1.21/test/select-tr-expr.3.out000066400000000000000000001317551467060157400200250ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##VEP="v110" time="2023-11-23 11:29:25" cache="/opt/vep/.vep/homo_sapiens/110_GRCh38" ensembl-funcgen=110.24e6da6 ensembl=110.584a8f3 ensembl-variation=110.d34d25e ensembl-io=110.b1a0d57 1000genomes="phase3" COSMIC="97" ClinVar="202301" HGMD-PUBLIC="20204" assembly="GRCh38.p14" dbSNP="154" gencode="GENCODE 44" genebuild="2014-07" gnomADe="r2.1.1" gnomADg="v3.1.2" polyphen="2.2.3" regbuild="1.0" sift="6.2.1" ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1789242 . T C . . CSQ=C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000378609|protein_coding|10/12||ENST00000378609.9:c.727A>G|ENSP00000367872.3:p.Thr243Ala|1090|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|YES|NM_002074.5||1|P1|CCDS34.1|ENSP00000367872|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.|||||||||0.581|-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|downstream_gene_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000434686|protein_coding||||||||||rs1394767075|1|4003|-1|cds_end_NF|SNV|HGNC|HGNC:4396||||3|||ENSP00000392765||F6UT28.70|UPI000268AE0F||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000439272|protein_coding|9/11||ENST00000439272.7:c.688A>G|ENSP00000399741.3:p.Thr230Ala|853|688|230|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5|||ENSP00000399741||F6X3N5.69|UPI0000D61E20||1|deleterious_low_confidence(0)|benign(0.094)|CDD:cd00200&PIRSF:PIRSF002394&Pfam:PF00400&Gene3D:2.130.10.10&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|non_coding_transcript_exon_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000461893|retained_intron|3/3||ENST00000461893.5:n.1183A>G||1183|||||rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||2||||||||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|non_coding_transcript_exon_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000471354|retained_intron|7/7||ENST00000471354.1:n.1331A>G||1331|||||rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5||||||||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000610897|protein_coding|9/11||ENST00000610897.4:c.727A>G|ENSP00000481878.1:p.Thr243Ala|1071|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5|P1|CCDS34.1|ENSP00000481878|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000615252|protein_coding|7/9||ENST00000615252.5:c.427A>G|ENSP00000483532.1:p.Thr143Ala|676|427|143|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5||CCDS72685.1|ENSP00000483532||B3KVK2.118|UPI00002177A7||1|deleterious_low_confidence(0)|possibly_damaging(0.906)|CDD:cd00200&Pfam:PF00400&Gene3D:2.130.10.10&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50294&PROSITE_profiles:PS50082&PANTHER:PTHR19850&AlphaFold_DB_import:AF-B3KVK2-F1|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703692|protein_coding|10/11||ENST00000703692.1:c.727A>G|ENSP00000515427.1:p.Thr243Ala|950|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515427||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703693|protein_coding|14/16||ENST00000703693.1:c.727A>G|ENSP00000515428.1:p.Thr243Ala|1437|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515428||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703694|protein_coding|9/10||ENST00000703694.1:c.727A>G|ENSP00000515429.1:p.Thr243Ala|824|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515429||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|synonymous_variant&NMD_transcript_variant|LOW|GNB1|ENSG00000078369|Transcript|ENST00000703695|nonsense_mediated_decay|9/11||ENST00000703695.1:c.525A>G|ENSP00000515430.1:p.Pro175%3D|690|525|175|P|ccA/ccG|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515430|||UPI0021EC8336||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703696|protein_coding|10/12||ENST00000703696.1:c.727A>G|ENSP00000515431.1:p.Thr243Ala|972|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515431||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703697|protein_coding|10/11||ENST00000703697.1:c.727A>G|ENSP00000515432.1:p.Thr243Ala|935|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515432||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|upstream_gene_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000703698|protein_coding_CDS_not_defined||||||||||rs1394767075|1|798|-1||SNV|HGNC|HGNC:4396||||||||||||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703699|protein_coding|10/11||ENST00000703699.1:c.727A>G|ENSP00000515433.1:p.Thr243Ala|892|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515433||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703700|protein_coding|10/12||ENST00000703700.1:c.727A>G|ENSP00000515434.1:p.Thr243Ala|851|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515434||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703701|protein_coding|12/14||ENST00000703701.1:c.727A>G|ENSP00000515435.1:p.Thr243Ala|1231|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515435||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703702|protein_coding|11/13||ENST00000703702.1:c.727A>G|ENSP00000515436.1:p.Thr243Ala|1035|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515436||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703703|protein_coding|10/12||ENST00000703703.1:c.727A>G|ENSP00000515437.1:p.Thr243Ala|998|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515437||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703704|protein_coding|12/14||ENST00000703704.1:c.727A>G|ENSP00000515438.1:p.Thr243Ala|1259|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515438||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703705|protein_coding|9/11||ENST00000703705.1:c.595A>G|ENSP00000515439.1:p.Thr199Ala|771|595|199|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515439|||UPI0000088585||1|deleterious_low_confidence(0)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703706|protein_coding|11/13||ENST00000703706.1:c.727A>G|ENSP00000515440.1:p.Thr243Ala|1049|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515440||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703707|protein_coding|8/10||ENST00000703707.1:c.688A>G|ENSP00000515441.1:p.Thr230Ala|815|688|230|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515441|||UPI0000D61E20||1|deleterious_low_confidence(0)|benign(0.094)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703708|protein_coding|13/15||ENST00000703708.1:c.727A>G|ENSP00000515442.1:p.Thr243Ala|1364|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515442||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703709|protein_coding|11/13||ENST00000703709.1:c.727A>G|ENSP00000515443.1:p.Thr243Ala|948|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515443||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703710|protein_coding|12/14||ENST00000703710.1:c.727A>G|ENSP00000515444.1:p.Thr243Ala|1276|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515444||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703711|protein_coding|13/15||ENST00000703711.1:c.727A>G|ENSP00000515445.1:p.Thr243Ala|1257|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515445||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344727|CTCF_binding_site||||||||||rs1394767075|1||||SNV||||||||||||||||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00001164872|enhancer||||||||||rs1394767075|1||||SNV||||||||||||||||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|||||||||||||||||||||||||||||||||| 1 1804496 . T C . . CSQ=C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000378609|protein_coding|7/12||ENST00000378609.9:c.353A>G|ENSP00000367872.3:p.Asp118Gly|716|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|YES|NM_002074.5||1|P1|CCDS34.1|ENSP00000367872|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0)|probably_damaging(0.982)||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000434686|protein_coding|8/9||ENST00000434686.6:c.353A>G|ENSP00000392765.2:p.Asp118Gly|540|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1|cds_end_NF|SNV|HGNC|HGNC:4396||||3|||ENSP00000392765||F6UT28.70|UPI000268AE0F||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&AlphaFold_DB_import:AF-F6UT28-F1&Pfam:PF00400&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|downstream_gene_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000437146|protein_coding||||||||||rs1553194162&CM1612300|1|30|-1|cds_end_NF|SNV|HGNC|HGNC:4396||||3|||ENSP00000416651||B1AKQ8.114|UPI0003F47E62||1||||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|||||||||||||||10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000439272|protein_coding|6/11||ENST00000439272.7:c.314A>G|ENSP00000399741.3:p.Asp105Gly|479|314|105|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5|||ENSP00000399741||F6X3N5.69|UPI0000D61E20||1|deleterious_low_confidence(0)|probably_damaging(0.993)|CDD:cd00200&PIRSF:PIRSF002394&Pfam:PF00400&Gene3D:2.130.10.10&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319&AlphaFold_DB_import:AF-F6X3N5-F1|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|non_coding_transcript_exon_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000471354|retained_intron|4/7||ENST00000471354.1:n.957A>G||957|||||rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5||||||||1||||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|||||||||||||||10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000610897|protein_coding|6/11||ENST00000610897.4:c.353A>G|ENSP00000481878.1:p.Asp118Gly|697|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5|P1|CCDS34.1|ENSP00000481878|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0)|probably_damaging(0.982)||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000615252|protein_coding|4/9||ENST00000615252.5:c.53A>G|ENSP00000483532.1:p.Asp18Gly|302|53|18|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5||CCDS72685.1|ENSP00000483532||B3KVK2.118|UPI00002177A7||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Superfamily:SSF50978&PANTHER:PTHR19850&AlphaFold_DB_import:AF-B3KVK2-F1|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703692|protein_coding|7/11||ENST00000703692.1:c.353A>G|ENSP00000515427.1:p.Asp118Gly|576|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515427||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703693|protein_coding|11/16||ENST00000703693.1:c.353A>G|ENSP00000515428.1:p.Asp118Gly|1063|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515428||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703694|protein_coding|6/10||ENST00000703694.1:c.353A>G|ENSP00000515429.1:p.Asp118Gly|450|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515429||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant&NMD_transcript_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703695|nonsense_mediated_decay|7/11||ENST00000703695.1:c.353A>G|ENSP00000515430.1:p.Asp118Gly|518|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515430|||UPI0021EC8336||1|deleterious_low_confidence(0)|probably_damaging(0.917)||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703696|protein_coding|7/12||ENST00000703696.1:c.353A>G|ENSP00000515431.1:p.Asp118Gly|598|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515431||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703697|protein_coding|7/11||ENST00000703697.1:c.353A>G|ENSP00000515432.1:p.Asp118Gly|561|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515432||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703699|protein_coding|7/11||ENST00000703699.1:c.353A>G|ENSP00000515433.1:p.Asp118Gly|518|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515433||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703700|protein_coding|7/12||ENST00000703700.1:c.353A>G|ENSP00000515434.1:p.Asp118Gly|477|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515434||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703701|protein_coding|9/14||ENST00000703701.1:c.353A>G|ENSP00000515435.1:p.Asp118Gly|857|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515435||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703702|protein_coding|8/13||ENST00000703702.1:c.353A>G|ENSP00000515436.1:p.Asp118Gly|661|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515436||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703703|protein_coding|7/12||ENST00000703703.1:c.353A>G|ENSP00000515437.1:p.Asp118Gly|624|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515437||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703704|protein_coding|9/14||ENST00000703704.1:c.353A>G|ENSP00000515438.1:p.Asp118Gly|885|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515438||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703705|protein_coding|6/11||ENST00000703705.1:c.221A>G|ENSP00000515439.1:p.Asp74Gly|397|221|74|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515439|||UPI0000088585||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703706|protein_coding|8/13||ENST00000703706.1:c.353A>G|ENSP00000515440.1:p.Asp118Gly|675|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515440||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703707|protein_coding|5/10||ENST00000703707.1:c.314A>G|ENSP00000515441.1:p.Asp105Gly|441|314|105|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515441|||UPI0000D61E20||1|deleterious_low_confidence(0)|probably_damaging(0.993)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703708|protein_coding|10/15||ENST00000703708.1:c.353A>G|ENSP00000515442.1:p.Asp118Gly|990|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515442||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703709|protein_coding|8/13||ENST00000703709.1:c.353A>G|ENSP00000515443.1:p.Asp118Gly|574|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515443||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703710|protein_coding|9/14||ENST00000703710.1:c.353A>G|ENSP00000515444.1:p.Asp118Gly|902|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515444||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703711|protein_coding|10/15||ENST00000703711.1:c.353A>G|ENSP00000515445.1:p.Asp118Gly|883|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515445||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1|| bcftools-1.21/test/setGT.1.out000066400000000000000000000042051467060157400161600ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 0/1:245 1 3000151 . C T 59.2 PASS . GT:DP:GQ 1/0:32:245 ./.:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 1 3106154 . C CT 59.2 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS . GT:GQ:DP ./.:212:22 ./.:212:22 1 3177144 . G T 45 PASS . GT:GQ:DP 0/0:150:30 0/0:150:30 1 3177144 . G . 45 PASS . GT:GQ:DP 0/0:150:30 0/0:150:30 1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP ./.:12:10 ./.:12:10 2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 bcftools-1.21/test/setGT.2.out000066400000000000000000000022721467060157400161630ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 HG00200 HG00201 HG00202 20 302 . T TA 999 . . GT:AD ./.:55,5 1|0:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 828 . T C 999 . . GT:AD ./.:55,5 1|1:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 834 . G A 999 . . GT:AD ./.:55,5 0|1:55,5 1|1:5,55 1|0:55,5 ./.:55,5 1|1:5,55 20 1665 . T C 999 . . GT:AD ./.:55,5 0|1:55,5 ./.:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 1869 . A T 999 . . GT:AD ./.:55,5 0|0:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 2041 . G A 999 . . GT:AD ./.:55,5 1|1:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 2220 . G A 999 . . GT:AD ./.:55,5 1|0:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 2564 . A G 999 . . GT:AD ./.:55,5 1|1:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 3104 . C T 999 . . GT:AD 0|0:5,5 0|0:5,5 ./.:5,5 0|1:5,5 ./.:5,5 1|1:5,5 20 3587 . G A 999 . . GT:AD ./.:5,5 0|1:5,5 1|1:5,5 0|1:5,5 ./.:5,5 1|1:5,5 20 3936 . A G 999 . . GT:AD ./.:1,2 1|1:3,4 1|1:5,6 0|1:7,8 ./.:9,1 1|1:2,3 bcftools-1.21/test/setGT.2.vcf000066400000000000000000000022721467060157400161320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 HG00200 HG00201 HG00202 20 302 . T TA 999 . . GT:AD 0|1:55,5 1|0:55,5 1|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 828 . T C 999 . . GT:AD 0|1:55,5 1|1:55,5 1|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 834 . G A 999 . . GT:AD 0|1:55,5 0|1:55,5 1|1:5,55 1|0:55,5 1|0:55,5 1|1:5,55 20 1665 . T C 999 . . GT:AD 1|0:55,5 0|1:55,5 0|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 1869 . A T 999 . . GT:AD 0|1:55,5 0|0:55,5 1|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 2041 . G A 999 . . GT:AD 0|1:55,5 1|1:55,5 1|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 2220 . G A 999 . . GT:AD 0|1:55,5 1|0:55,5 1|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 2564 . A G 999 . . GT:AD 0|1:55,5 1|1:55,5 1|1:5,55 0|1:55,5 1|0:55,5 1|1:5,55 20 3104 . C T 999 . . GT:AD 0|0:5,5 0|0:5,5 0|1:5,5 0|1:5,5 1|0:5,5 1|1:5,5 20 3587 . G A 999 . . GT:AD 0|1:5,5 0|1:5,5 1|1:5,5 0|1:5,5 1|0:5,5 1|1:5,5 20 3936 . A G 999 . . GT:AD 0|1:1,2 1|1:3,4 1|1:5,6 0|1:7,8 1|0:9,1 1|1:2,3 bcftools-1.21/test/setGT.3.1.out000066400000000000000000000005571467060157400163270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 1|1 1|1 1 1 3000150 . C T,A . PASS . GT 2|2 2|2 2 1 3000150 . C . . PASS . GT 0|0 0|0 0 bcftools-1.21/test/setGT.3.2.out000066400000000000000000000005571467060157400163300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 0|0 0|0 0 1 3000150 . C T,A . PASS . GT 1|1 1|1 1 1 3000150 . C . . PASS . GT 0|0 0|0 0 bcftools-1.21/test/setGT.3.3.out000066400000000000000000000005431467060157400163240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 1 1 1 1 3000150 . C T,A . PASS . GT 1 1 1 1 3000150 . C . . PASS . GT . . . bcftools-1.21/test/setGT.3.4.out000066400000000000000000000005651467060157400163310ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 1|1 1|1 1|1 1 3000150 . C T,A . PASS . GT 1|1 1|1 1|1 1 3000150 . C . . PASS . GT ./. ./. ./. bcftools-1.21/test/setGT.3.5.out000066400000000000000000000005651467060157400163320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 0|1 0|1 0|1 1 3000150 . C T,A . PASS . GT 1|2 1|2 1|2 1 3000150 . C . . PASS . GT 0|0 0|0 0|0 bcftools-1.21/test/setGT.3.6.out000066400000000000000000000006071467060157400163300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 0/1/1 0/1/1 0/1/1 1 3000150 . C T,A . PASS . GT 0/1/1 0/1/1 0/1/1 1 3000150 . C . . PASS . GT 0/./. 0/./. 0/./. bcftools-1.21/test/setGT.3.out000066400000000000000000000022721467060157400161640ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 HG00200 HG00201 HG00202 20 302 . T TA 999 . . GT:AD ./.:55,5 1|0:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 828 . T C 999 . . GT:AD ./.:55,5 1|1:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 834 . G A 999 . . GT:AD ./.:55,5 0|1:55,5 1|1:5,55 1|0:55,5 ./.:55,5 1|1:5,55 20 1665 . T C 999 . . GT:AD ./.:55,5 0|1:55,5 ./.:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 1869 . A T 999 . . GT:AD ./.:55,5 0|0:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 2041 . G A 999 . . GT:AD ./.:55,5 1|1:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 2220 . G A 999 . . GT:AD ./.:55,5 1|0:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 2564 . A G 999 . . GT:AD ./.:55,5 1|1:55,5 1|1:5,55 0|1:55,5 ./.:55,5 1|1:5,55 20 3104 . C T 999 . . GT:AD 0|0:5,5 0|0:5,5 0|1:5,5 0|1:5,5 1|0:5,5 1|1:5,5 20 3587 . G A 999 . . GT:AD 0|1:5,5 0|1:5,5 1|1:5,5 0|1:5,5 1|0:5,5 1|1:5,5 20 3936 . A G 999 . . GT:AD 0|1:1,2 1|1:3,4 1|1:5,6 0|1:7,8 ./.:9,1 1|1:2,3 bcftools-1.21/test/setGT.3.vcf000066400000000000000000000004731467060157400161340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fa ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 3000150 . C T . PASS . GT 0/0 1/1 1 1 3000150 . C T,A . PASS . GT 1/1 2/2 2 1 3000150 . C . . PASS . GT ./. ./. . bcftools-1.21/test/setGT.4.1.out000066400000000000000000000007331467060157400163240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A C 1 1890 . A G . . . GT:DP ./.:12 0/0:102 ./.:10 1 1991 . G T . . . GT:DP ./.:8 0/1:100 ./.:11 bcftools-1.21/test/setGT.4.2.out000066400000000000000000000007331467060157400163250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A C 1 1890 . A G . . . GT:DP ./.:12 0/0:102 ./.:10 1 1991 . G T . . . GT:DP ./.:8 ./.:100 ./.:11 bcftools-1.21/test/setGT.4.vcf000066400000000000000000000006651467060157400161400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A C 1 1890 . A G . . . GT:DP 1/1:12 0/0:102 0/1:10 1/1:20 1 1991 . G T . . . GT:DP 1/1:8 0/1:100 0/0:11 0/0:11 bcftools-1.21/test/setGT.5.1.out000066400000000000000000000005461467060157400163270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:ref.fa ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 1890 . A G . . . GT:AD 0/0:10,0 1/1:0,10 bcftools-1.21/test/setGT.5.2.out000066400000000000000000000005521467060157400163250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:ref.fa ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 1890 . A G . . . GT:AD 0/0/0:10,0 0/1/1:0,10 bcftools-1.21/test/setGT.5.vcf000066400000000000000000000004621467060157400161340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=file:ref.fa ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 1890 . A G . . . GT:AD ./.:10,0 ./.:0,10 bcftools-1.21/test/setGT.6.1.out000066400000000000000000000004501467060157400163220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:ref.fa ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 1890 . A G . . . GT ./. ./. 1/1 1|1 bcftools-1.21/test/setGT.6.2.out000066400000000000000000000004501467060157400163230ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##reference=file:ref.fa ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 1890 . A G . . . GT ./. 1|. ./. 1|1 bcftools-1.21/test/setGT.6.vcf000066400000000000000000000003641467060157400161360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##reference=file:ref.fa ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D 1 1890 . A G . . . GT 1/. 1|. 1/1 1|1 bcftools-1.21/test/setGT.samples.txt000066400000000000000000000000301467060157400174640ustar00rootroot00000000000000HG00100 HG00102 HG00201 bcftools-1.21/test/setGT.vcf000066400000000000000000000042051467060157400157700ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##INFO= ##FORMAT= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##test= ##readme=AAAAAA ##readme=BBBBBB ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 0/1:245 1 3000151 . C T 59.2 PASS . GT:DP:GQ 1/0:32:245 ./.:32:245 1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 1 3106154 . CAAA C 342 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 1 3106154 . C CT 59.2 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 1 3162006 . GAA G 60.2 PASS . GT:GQ:DP ./.:212:22 ./.:212:22 1 3177144 . G T 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 1 3177144 . G . 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP ./.:12:10 ./.:12:10 2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 bcftools-1.21/test/smpl-stats.1.out000066400000000000000000000027161467060157400172460ustar00rootroot00000000000000# CMD line shows the command line used to generate this output # DEF lines define expressions for all tested thresholds # FLT* lines report numbers for every threshold and every sample: # 1) filter id # 2) sample # 3) number of genotypes which pass the filter # 4) number of non-reference genotypes # 5) number of homozygous ref genotypes (0/0 or 0) # 6) number of homozygous alt genotypes (1/1, 2/2, etc) # 7) number of heterozygous genotypes (0/1, 1/2, etc) # 8) number of hemizygous genotypes (0, 1, etc) # 9) number of SNVs # 10) number of indels # 11) number of singletons # 12) number of missing genotypes (./., ., ./0, etc) # 13) number of transitions (alt het genotypes such as "1/2" are counted twice) # 14) number of transversions (alt het genotypes such as "1/2" are counted twice) # 15) overall ts/tv # SITE* lines report numbers for every threshold: # 1) filter id # 2) number of sites which pass the filter # 3) number of SNVs # 4) number of indels # 5) number of singletons # 6) number of transitions (counted at most once at multiallelic sites) # 7) number of transversions (counted at most once at multiallelic sites) # 8) overall ts/tv DEF FLT0 all FLT0 child1 4 4 0 2 2 0 1 3 1 0 0 1 0.00 FLT0 father1 4 2 2 1 1 0 1 1 0 0 0 1 0.00 FLT0 mother1 4 1 3 1 0 0 1 0 0 0 0 1 0.00 FLT0 child2 4 2 2 0 2 0 1 1 0 0 1 1 1.00 FLT0 father2 3 1 2 0 1 0 1 0 0 1 1 1 1.00 FLT0 mother2 4 1 3 1 0 0 1 0 0 0 0 1 0.00 SITE0 4 1 3 1 1 1 1.00 bcftools-1.21/test/sort.out000066400000000000000000000002601467060157400157570ustar00rootroot000000000000001 101 T,C,A 1 101 T,CC,A 1 101 T,TC 1 102 T,C 1 103 T,C 1 104 T,C 1 105 T,C 2 101 T,C 2 102 T,C 2 103 T,C 2 104 T,C 2 105 T,C 3 101 T,C 3 102 T,C 3 103 T,C 3 104 T,C 3 105 T,C bcftools-1.21/test/sort.vcf000066400000000000000000000007651467060157400157400ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 3 105 . T C . . . 3 104 . T C . . . 3 103 . T C . . . 3 102 . T C . . . 3 101 . T C . . . 2 105 . T C . . . 2 104 . T C . . . 2 103 . T C . . . 2 102 . T C . . . 2 101 . T C . . . 1 105 . T C . . . 1 104 . T C . . . 1 103 . T C . . . 1 102 . T C . . . 1 101 . T TC . . . 1 101 . T C,A . . . 1 101 . T CC,A . . . bcftools-1.21/test/split-vep.1.out000066400000000000000000000164051467060157400170620ustar00rootroot0000000000000014464 . 14469 . 14522 . 14542 . 14574 . 14590 . 14599 . 14653 . 14671 . 14673 . 14677 . 14696 . 14699 . 14729 . 14747 . 14763 . 14773 . 14815 . 14842 . 14843 . 14860 . 14863 . 14891 . 14896 . 14907 . 14908 . 14929 . 14930 . 14931 . 14933 . 14935 . 14936 . 14938 . 14947 . 14948 . 14949 . 14955 . 14956 . 14959 . 14961 . 14971 . 14974 . 14976 . 14978 . 15004 splice_donor_variant&non_coding_transcript_variant 15029 . 15038 . 15058 . 15065 . 15072 . 15086 . 15112 . 15118 . 15688 . 15759 . 15773 . 15776 . 15777 . 15787 . 15811 . 15817 . 15820 . 15903 . 15906 . 15908 . 15912 . 15922 . 15974 . 15989 . 16014 . 16495 . 16497 . 16534 . 16571 . 16580 . 16682 . 16719 . 16792 . 16825 . 16841 . 16856 splice_donor_variant&non_coding_transcript_variant 16957 . 16977 . 17020 . 17222 . 17289 . 17358 . 17365 splice_acceptor_variant&non_coding_transcript_variant 17373 . 17375 . 17378 . 17379 . 17385 . 17398 . 17403 . 17406 . 17407 . 17408 . 17427 . 17444 . 17450 . 17452 . 17453 . 17455 . 17478 . 17479 . 17483 . 17484 . 17487 . 17490 . 17493 . 17501 . 17512 . 17516 . 17519 . 17527 . 17528 . 17538 . 17540 . 17556 . 17559 . 17562 . 17563 . 17585 . 17589 . 17594 . 17606 . 17614 . 17626 . 17636 . 17639 . 17645 . 17647 . 17652 . 17694 . 17695 . 17697 . 17701 . 17709 . 17716 . 17722 . 17728 . 17730 . 17746 . 17765 . 17805 . 17829 . 19190 . 19217 . 19226 . 19234 . 19236 . 19249 . 19254 . 62904 . 62905 . 62926 . 62950 . 62966 . 63093 . 63165 . 63210 . 63212 . 63307 . 63336 . 63415 . 63437 . 63458 . 63495 . 63516 . 63527 . 63528 . 63615 . 63627 . 63628 . 63642 . 63643 . 63654 . 63668 . 63671 . 63687 . 63697 . 63703 . 63708 . 63714 . 63717 . 63722 . 63735 . 63778 . 63791 . 65797 . 65843 . 65851 . 65864 . 65868 . 65872 . 65875 . 65892 . 65898 . 65900 . 65907 . 65910 . 65918 . 65973 . 65974 . 65975 . 65992 . 66026 . 66041 . 66042 . 66053 . 66055 . 69270 . 69428 missense_variant 69438 . 69453 . 69469 frameshift_variant 69486 . 69489 . 69496 missense_variant 69511 missense_variant 69552 . 69559 missense_variant 69561 . 69569 missense_variant 69590 missense_variant 69594 . 69604 missense_variant 69610 missense_variant 69634 missense_variant 69640 missense_variant 69678 missense_variant 69690 . 69696 . 69713 missense_variant 69719 stop_gained 69761 missense_variant 69808 missense_variant 69816 missense_variant 69897 . 120705 . 120745 . 120866 . 120871 . 120895 . 120961 . 120969 . 120983 . 120991 . 120994 . 120998 . 121009 . 121028 . 129077 . 129122 . 129148 . 129285 . 129301 . 129315 . 133355 . 133392 . 133477 . 133483 . 133558 . 135147 . 135151 . 135156 . 135162 . 135163 . 135172 . 135173 . 135178 . 135187 . 135193 . 135195 . 135196 . 135203 . 135215 . 135224 . 135232 . 135265 . 135297 . 135982 . 136041 . 136048 . 136060 . 136068 . 136073 . 136082 . 136113 . 136124 . 136210 . 137622 . 137825 . 267027 . 267069 . 267083 . 267099 . 267132 . 267147 . 267154 . 267216 . 267220 . 267226 . 267227 . 267229 . 267268 . 267276 . 267282 . 267289 . 267293 . 267294 . 267295 . 267300 . 267303 . 267305 . 267309 . 267310 . 267316 . 267319 . 267324 . 267331 . 267355 . 267359 . 647265 . 647380 . 647398 . 662029 . 662414 . 662531 . 662613 . 662622 . 662623 . 662843 . 662857 . 663083 . 663097 . 717379 . 717396 . 717432 . 717474 . 717481 . 717485 . 717486 . 717519 . 717534 . 717574 . 721256 . 721288 . 721290 . 721302 . 721303 . 721311 . 721323 . 721332 . 721361 . 721371 . 721409 . 721426 . 721439 . 721450 . 721462 . 721478 . 721538 . 721540 . 721548 . 721549 . 721554 . 721566 . 721569 . 721575 . 721576 . 721642 . 721645 . 721668 . 721682 . 721694 . 721699 . 721705 . 721707 . 721708 . 721722 . 721724 . 721735 . 721748 . 721750 . 721757 . 721772 . 721783 . 721788 . 721798 . 721806 . 721836 . 721847 . 721867 . 721873 . 721884 . 721891 . 721905 . 721915 . 721945 . 721948 . 721964 . 721977 . 721984 . 721994 . 721996 . 722025 . 722032 . 741163 . 741181 . 741235 . 741260 . 741267 . 741286 . 745347 . 745370 . 745425 . 745439 . 745477 . 745573 . 745620 . 745642 . 752737 . 752745 . 752748 . 752752 splice_donor_variant&non_coding_transcript_variant 752770 . 752796 . 752802 . 752809 . 752841 . 752872 . 752873 . 752894 . 752915 . 752918 . 752938 . 752950 . 752996 . 753001 . 753016 . 753110 . 753168 . 753174 . 753185 . 753235 . 753263 . 753269 . 753291 . 753338 . 753405 . 753423 . 753424 . 753425 . 753426 . 753433 . 753444 . 753474 . 753479 . 762005 . 762008 . 762022 . 762031 . 762033 . 762037 . 762038 . 762045 . 762052 . 762061 . 762069 . 762070 . 762085 . 762092 . 762109 . 762142 . 762159 . 762175 . 762187 . 762190 . 762199 . 762203 . 762211 . 762215 . 762222 . 762224 . 762249 . 762262 . 762273 . 762277 . 762292 . 762307 . 762320 . 762330 . 762339 . 762345 . 762352 . 762366 . 762383 . 762409 . 762413 . 762418 . 762423 . 762426 . 762446 . 762449 . 762460 . 762465 . 762469 . 762472 . 762475 . 762485 . 762486 . 762489 . 762494 . 762523 . 762538 . 762588 . 762589 . 762592 . 762595 . 762601 . 762604 . 762632 . 762637 . 777161 . 777175 . 777180 . 777183 . 777184 . 777189 . 777203 . 777232 . 777233 . 777237 . 777238 . 777242 . 777245 . 777256 . 777269 . 777288 . 777312 . 777317 . 777318 . 777348 . 777361 . 777379 . 777390 . 777392 . 777423 . 777431 . 777437 . 777444 . 777448 . 777449 . 777456 . 777459 . 777481 . 777498 . 777508 . 777512 . 777513 . 777516 . 777558 . 777564 . 777575 . 777578 . 777579 . 777581 . 777582 . 777588 . 777617 . 777636 . 777637 . 777654 . 777664 . 777670 . 777679 . 777683 . 777690 . 777699 . 777714 . 782980 . 782981 . 782982 . 783005 . 783015 . 783042 . 783049 . 783050 . 783060 . 783070 . 783071 . 783090 . 783095 . 783096 . 783101 . 783107 . 783124 . 783129 . 783142 . 783147 . 783150 . 783151 . 783174 . 783175 . 783180 . 783186 . 783193 . 783194 . 783209 . 783211 . 783226 . 783245 . 783249 . 792185 . 792194 . 792195 . 792207 . 792241 . 792254 . 792263 . 792264 . 792272 . 792276 . 792280 . 792288 . 792299 . 792300 . 792328 . 792346 . 792349 . 792355 . 792368 . 792373 . 792379 . 792392 . 792399 . 792405 . 792410 . 792423 . 792441 . 792443 . 792447 . 792448 . 792453 . 792480 . 792493 . 792496 . 792497 . 792506 . 792517 . 792523 . 792534 . 792537 . 792540 . 808659 . 808662 . 808665 . 808672 . 808695 . 808708 . 808710 . 808714 . 808723 . 808724 . 808725 . 808728 . 808729 . 808749 . 808756 . 808774 . 808788 . 808793 . 808816 . 808837 . 808845 . 808848 . 808861 . 808879 . 808888 . 808898 . 808899 . 808909 . 808922 . 808928 . 808929 . 808938 . 808957 . 808962 . 808984 . 808998 . 809001 . 809006 . 809007 . 809017 . 809022 . 809043 . 809091 . 809097 . 809107 . 809115 . 809116 . 809123 . 809136 . 809146 . 809150 . 809157 . 809171 . 809178 . 809213 . 809221 . 809237 . 809238 . 809242 . 809248 . 809261 . 809268 . 809273 . 809301 . 809319 . 809326 . 809329 . 809330 . 809346 . 809347 . 809351 . 809352 . 809353 . 809379 . 809385 . 809407 . 809427 . 809430 . 809434 . 809439 . 809446 . 809447 . 809451 . 809454 . 809464 . 809469 . 809470 . 809510 . 809533 . 809534 . 809535 . 809558 . 809563 . 809565 . 809572 . 809582 . 809590 . 809591 . 809594 . 809595 . 809596 . 809602 . 809615 . 809621 . 809622 . 809624 . 809628 . 809638 . 809680 . 809681 . 809687 . 809690 . 809700 . 809707 . 809711 . 809732 . 809741 . 809744 . 809752 . 809756 . 809761 . 809763 . 809764 . 809766 . 809768 . 860416 . 860417 . 860431 . 860461 . 860498 . 860504 . 860511 . 860521 . 860564 . 860604 . 860607 . 860637 . 860684 . 860688 . 861172 . 861177 . 861178 . 861196 . 861209 . 861211 . 861213 . bcftools-1.21/test/split-vep.10.out000066400000000000000000000004351467060157400171360ustar00rootroot0000000000000014464 . non_coding_transcript_exon_variant 14464 YES non_coding_transcript_exon_variant 14464 YES downstream_gene_variant 14464 . non_coding_transcript_exon_variant 14464 . non_coding_transcript_exon_variant 14464 . non_coding_transcript_exon_variant 14464 . regulatory_region_variant bcftools-1.21/test/split-vep.10.vcf000066400000000000000000000027421467060157400171100ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 9 94487044 . C T . . CSQ=T|missense_variant|MODERATE|ROR2|ENSG00000169071|Transcript|ENST00000375708|protein_coding|9/9||ENST00000375708.3:c.1732G>A|ENSP00000364860.3:p.Asp578Asn|1931|1732|578|D/N|Gat/Aat|rs139802697||-1||SNV|HGNC|10257|YES|||||CCDS6691.1|ENSP00000364860|ROR2_HUMAN||UPI000013E8CA||1|tolerated(0.13)|probably_damaging(0.999)|Superfamily:SSF56112&PIRSF:PIRSF000624&Gene3D:1.10.510.10&Pfam:PF07714&PANTHER:PTHR24416:SF132&PANTHER:PTHR24416&PROSITE_profiles:PS50011|||||||||0.000227|0|3.192e-05|6.165e-05|5.789e-05|0|0|0|4.416e-05|0|0|0.000227|AA||||||||||0.46|23.5|2.953273|D|0.293271| bcftools-1.21/test/split-vep.11.out000066400000000000000000000045641467060157400171460ustar00rootroot0000000000000014464 T,T,T,T,T,T,T non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,downstream_gene_variant,non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,regulatory_region_variant MODIFIER,MODIFIER,MODIFIER,MODIFIER,MODIFIER,MODIFIER,MODIFIER WASH7P,WASH7P,DDX11L1,WASH7P,WASH7P,WASH7P,. ENSG00000227232,ENSG00000227232,ENSG00000223972,ENSG00000227232,ENSG00000227232,ENSG00000227232,. Transcript,Transcript,Transcript,Transcript,Transcript,Transcript,RegulatoryFeature ENST00000423562,ENST00000438504,ENST00000456328,ENST00000488147,ENST00000538476,ENST00000541675,ENSR00000000002 unprocessed_pseudogene,unprocessed_pseudogene,processed_transcript,unprocessed_pseudogene,unprocessed_pseudogene,unprocessed_pseudogene,open_chromatin_region 10/10,12/12,.,11/11,13/13,9/9,. .,.,.,.,.,.,. ENST00000423562.1:n.1568T>A,ENST00000438504.2:n.1682T>A,.,ENST00000488147.1:n.1291T>A,ENST00000538476.1:n.1530T>A,ENST00000541675.1:n.1315T>A,. .,.,.,.,.,.,. 1568,1682,.,1291,1530,1315,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. rs546169444,rs546169444,rs546169444,rs546169444,rs546169444,rs546169444,rs546169444 1,1,1,1,1,1,1 .,.,55,.,.,.,. -1,-1,1,-1,-1,-1,. .,.,.,.,.,.,. SNV,SNV,SNV,SNV,SNV,SNV,SNV HGNC,HGNC,HGNC,HGNC,HGNC,HGNC,. 38034,38034,37102,38034,38034,38034,. .,YES,YES,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. 0.0958,0.0958,0.0958,0.0958,0.0958,0.0958,0.0958 0.0144,0.0144,0.0144,0.0144,0.0144,0.0144,0.0144 0.1138,0.1138,0.1138,0.1138,0.1138,0.1138,0.1138 0.005,0.005,0.005,0.005,0.005,0.005,0.005 0.1859,0.1859,0.1859,0.1859,0.1859,0.1859,0.1859 0.1943,0.1943,0.1943,0.1943,0.1943,0.1943,0.1943 .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. 0.1943,0.1943,0.1943,0.1943,0.1943,0.1943,0.1943 SAS,SAS,SAS,SAS,SAS,SAS,SAS .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. .,.,.,.,.,.,. bcftools-1.21/test/split-vep.12.2.out000066400000000000000000000071131467060157400173000ustar00rootroot00000000000000#[1]POS [2]Allele [3]Consequence [4]IMPACT [5]SYMBOL [6]Gene [7]Feature_type [8]Feature [9]BIOTYPE [10]EXON [11]INTRON [12]HGVSc [13]HGVSp [14]cDNA_position [15]CDS_position [16]Protein_position [17]Amino_acids [18]Codons [19]Existing_variation [20]ALLELE_NUM [21]DISTANCE [22]STRAND [23]FLAGS [24]VARIANT_CLASS [25]SYMBOL_SOURCE [26]HGNC_ID [27]CANONICAL [28]TSL [29]APPRIS [30]CCDS [31]ENSP [32]SWISSPROT [33]TREMBL [34]UNIPARC [35]SOURCE [36]GENE_PHENO [37]SIFT [38]PolyPhen [39]DOMAINS [40]miRNA [41]HGVS_OFFSET [42]AF [43]AFR_AF [44]AMR_AF [45]EAS_AF [46]EUR_AF [47]SAS_AF [48]AA_AF [49]EA_AF [50]gnomAD_AF [51]gnomAD_AFR_AF [52]gnomAD_AMR_AF [53]gnomAD_ASJ_AF [54]gnomAD_EAS_AF [55]gnomAD_FIN_AF [56]gnomAD_NFE_AF [57]gnomAD_OTH_AF [58]gnomAD_SAS_AF [59]MAX_AF [60]MAX_AF_POPS [61]CLIN_SIG [62]SOMATIC [63]PHENO [64]PUBMED [65]MOTIF_NAME [66]MOTIF_POS [67]HIGH_INF_POS [68]MOTIF_SCORE_CHANGE [69]LoF [70]LoF_filter [71]LoF_flags [72]LoF_info [73]CADD_PHRED [74]CADD_RAW [75]gnomAD2.1 [76]gnomAD2.1_AF_raw [77]gnomAD2.1_AF_popmax [78]gnomAD2.1_AF_afr [79]gnomAD2.1_AF_amr [80]gnomAD2.1_AF_asj [81]gnomAD2.1_AF_eas [82]gnomAD2.1_AF_fin [83]gnomAD2.1_AF_nfe [84]gnomAD2.1_AF_oth [85]gnomAD2.1_AF_sas 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000423562 unprocessed_pseudogene 10/10 . ENST00000423562.1:n.1568T>A . 1568 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000438504 unprocessed_pseudogene 12/12 . ENST00000438504.2:n.1682T>A . 1682 . . . . rs546169444 1 . -1 . SNV HGNC 38034 YES . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T downstream_gene_variant MODIFIER DDX11L1 ENSG00000223972 Transcript ENST00000456328 processed_transcript . . . . . . . . . rs546169444 1 55 1 . SNV HGNC 37102 YES . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000488147 unprocessed_pseudogene 11/11 . ENST00000488147.1:n.1291T>A . 1291 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000538476 unprocessed_pseudogene 13/13 . ENST00000538476.1:n.1530T>A . 1530 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000541675 unprocessed_pseudogene 9/9 . ENST00000541675.1:n.1315T>A . 1315 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T regulatory_region_variant MODIFIER . . RegulatoryFeature ENSR00000000002 open_chromatin_region . . . . . . . . . rs546169444 1 . . . SNV . . . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . bcftools-1.21/test/split-vep.12.3.out000066400000000000000000000064001467060157400172770ustar00rootroot00000000000000#POS Allele Consequence IMPACT SYMBOL Gene Feature_type Feature BIOTYPE EXON INTRON HGVSc HGVSp cDNA_position CDS_position Protein_position Amino_acids Codons Existing_variation ALLELE_NUM DISTANCE STRAND FLAGS VARIANT_CLASS SYMBOL_SOURCE HGNC_ID CANONICAL TSL APPRIS CCDS ENSP SWISSPROT TREMBL UNIPARC SOURCE GENE_PHENO SIFT PolyPhen DOMAINS miRNA HGVS_OFFSET AF AFR_AF AMR_AF EAS_AF EUR_AF SAS_AF AA_AF EA_AF gnomAD_AF gnomAD_AFR_AF gnomAD_AMR_AF gnomAD_ASJ_AF gnomAD_EAS_AF gnomAD_FIN_AF gnomAD_NFE_AF gnomAD_OTH_AF gnomAD_SAS_AF MAX_AF MAX_AF_POPS CLIN_SIG SOMATIC PHENO PUBMED MOTIF_NAME MOTIF_POS HIGH_INF_POS MOTIF_SCORE_CHANGE LoF LoF_filter LoF_flags LoF_info CADD_PHRED CADD_RAW gnomAD2.1 gnomAD2.1_AF_raw gnomAD2.1_AF_popmax gnomAD2.1_AF_afr gnomAD2.1_AF_amr gnomAD2.1_AF_asj gnomAD2.1_AF_eas gnomAD2.1_AF_fin gnomAD2.1_AF_nfe gnomAD2.1_AF_oth gnomAD2.1_AF_sas 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000423562 unprocessed_pseudogene 10/10 . ENST00000423562.1:n.1568T>A . 1568 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000438504 unprocessed_pseudogene 12/12 . ENST00000438504.2:n.1682T>A . 1682 . . . . rs546169444 1 . -1 . SNV HGNC 38034 YES . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T downstream_gene_variant MODIFIER DDX11L1 ENSG00000223972 Transcript ENST00000456328 processed_transcript . . . . . . . . . rs546169444 1 55 1 . SNV HGNC 37102 YES . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000488147 unprocessed_pseudogene 11/11 . ENST00000488147.1:n.1291T>A . 1291 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000538476 unprocessed_pseudogene 13/13 . ENST00000538476.1:n.1530T>A . 1530 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000541675 unprocessed_pseudogene 9/9 . ENST00000541675.1:n.1315T>A . 1315 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T regulatory_region_variant MODIFIER . . RegulatoryFeature ENSR00000000002 open_chromatin_region . . . . . . . . . rs546169444 1 . . . SNV . . . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . bcftools-1.21/test/split-vep.12.out000066400000000000000000000046301467060157400171410ustar00rootroot0000000000000014464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000423562 unprocessed_pseudogene 10/10 . ENST00000423562.1:n.1568T>A . 1568 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000438504 unprocessed_pseudogene 12/12 . ENST00000438504.2:n.1682T>A . 1682 . . . . rs546169444 1 . -1 . SNV HGNC 38034 YES . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T downstream_gene_variant MODIFIER DDX11L1 ENSG00000223972 Transcript ENST00000456328 processed_transcript . . . . . . . . . rs546169444 1 55 1 . SNV HGNC 37102 YES . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000488147 unprocessed_pseudogene 11/11 . ENST00000488147.1:n.1291T>A . 1291 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000538476 unprocessed_pseudogene 13/13 . ENST00000538476.1:n.1530T>A . 1530 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T non_coding_transcript_exon_variant MODIFIER WASH7P ENSG00000227232 Transcript ENST00000541675 unprocessed_pseudogene 9/9 . ENST00000541675.1:n.1315T>A . 1315 . . . . rs546169444 1 . -1 . SNV HGNC 38034 . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . 14464 T regulatory_region_variant MODIFIER . . RegulatoryFeature ENSR00000000002 open_chromatin_region . . . . . . . . . rs546169444 1 . . . SNV . . . . . . . . . . . . . . . . . 0.0958 0.0144 0.1138 0.005 0.1859 0.1943 . . . . . . . . . . . 0.1943 SAS . . . . . . . . . . . . . . . . . . . . . . . . . bcftools-1.21/test/split-vep.13.out000066400000000000000000000163531467060157400171470ustar00rootroot0000000000000014464 non_coding WASH7P . unprocessed_pseudogene . . . 69270 synonymous OR4F5 ENST00000335137 protein_coding + 60S 69270A>G 69428 missense OR4F5 ENST00000335137 protein_coding + 113F>113C 69428T>G 69438 synonymous OR4F5 ENST00000335137 protein_coding + 116Y 69438T>C 69453 synonymous OR4F5 ENST00000335137 protein_coding + 121K 69453G>A 69640 missense OR4F5 ENST00000335137 protein_coding + 184D>184H 69640G>C 69678 missense OR4F5 ENST00000335137 protein_coding + 196S>196R 69678T>A 69690 synonymous OR4F5 ENST00000335137 protein_coding + 200T 69690T>A 69696 synonymous OR4F5 ENST00000335137 protein_coding + 202C 69696T>C 69713 missense OR4F5 ENST00000335137 protein_coding + 208I>208T 69713T>C 69719 stop_gained OR4F5 ENST00000335137 protein_coding + 210S>210* 69719C>G 69761 missense OR4F5 ENST00000335137 protein_coding + 224D>224V 69761A>T 69808 missense OR4F5 ENST00000335137 protein_coding + 240V>240L 69808G>C 69816 missense OR4F5 ENST00000335137 protein_coding + 242L>242F 69816G>C 69897 synonymous OR4F5 ENST00000335137 protein_coding + 269S 69897T>C 120705 non_coding RP11-34P13.7 . lincRNA . . . 120745 non_coding RP11-34P13.7 . lincRNA . . . 121028 non_coding RP11-34P13.7 . lincRNA . . . 129077 non_coding RP11-34P13.7 . lincRNA . . . 129122 non_coding RP11-34P13.7 . lincRNA . . . 129148 non_coding RP11-34P13.7 . lincRNA . . . 129285 non_coding RP11-34P13.7 . lincRNA . . . 129301 non_coding RP11-34P13.7 . lincRNA . . . 129315 non_coding RP11-34P13.7 . lincRNA . . . 133355 non_coding RP11-34P13.7 . lincRNA . . . 133355 non_coding CICP27 . processed_pseudogene . . . 133392 non_coding RP11-34P13.7 . lincRNA . . . 133392 non_coding CICP27 . processed_pseudogene . . . 133477 non_coding RP11-34P13.7 . lincRNA . . . 133477 non_coding CICP27 . processed_pseudogene . . . 133483 non_coding RP11-34P13.7 . lincRNA . . . 133483 non_coding CICP27 . processed_pseudogene . . . 133558 non_coding RP11-34P13.7 . lincRNA . . . 133558 non_coding CICP27 . processed_pseudogene . . . 135147 3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 135151 3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 135232 3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 135265 3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 135297 3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 135982 intron AL627309.1 . protein_coding . . . 136041 intron AL627309.1 . protein_coding . . . 136124 intron AL627309.1 . protein_coding . . . 136210 intron AL627309.1 . protein_coding . . . 137622 splice_region&3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 137825 3_prime_utr AL627309.1 ENST00000423372 protein_coding . . . 267099 non_coding AP006222.2 . lincRNA . . . 267132 non_coding AP006222.2 . lincRNA . . . 267147 non_coding AP006222.2 . lincRNA . . . 267154 non_coding AP006222.2 . lincRNA . . . 267216 non_coding AP006222.2 . lincRNA . . . 267220 non_coding AP006222.2 . lincRNA . . . 267226 non_coding AP006222.2 . lincRNA . . . 267227 non_coding AP006222.2 . lincRNA . . . 267229 non_coding AP006222.2 . lincRNA . . . 647265 non_coding RP5-857K21.4 . lincRNA . . . 647380 non_coding RP5-857K21.4 . lincRNA . . . 647398 non_coding RP5-857K21.4 . lincRNA . . . 662029 non_coding RP11-206L10.1 . unprocessed_pseudogene . . . 662414 non_coding RP11-206L10.1 . unprocessed_pseudogene . . . 662531 non_coding RP11-206L10.1 . unprocessed_pseudogene . . . 722032 non_coding RP11-206L10.9 . lincRNA . . . 741163 non_coding RP11-206L10.9 . lincRNA . . . 741163 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 741163 non_coding RP11-206L10.8 . processed_transcript . . . 741181 non_coding RP11-206L10.9 . lincRNA . . . 741181 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 741181 non_coding RP11-206L10.8 . processed_transcript . . . 741235 non_coding RP11-206L10.9 . lincRNA . . . 741235 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 741235 non_coding RP11-206L10.8 . processed_transcript . . . 741260 non_coding RP11-206L10.9 . lincRNA . . . 741260 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 741260 non_coding RP11-206L10.8 . processed_transcript . . . 741286 non_coding RP11-206L10.9 . lincRNA . . . 741286 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 741286 non_coding RP11-206L10.8 . processed_transcript . . . 745347 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 745347 non_coding RP11-206L10.8 . processed_transcript . . . 745347 non_coding RP11-206L10.9 . lincRNA . . . 745370 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 745370 non_coding RP11-206L10.8 . processed_transcript . . . 745370 non_coding RP11-206L10.9 . lincRNA . . . 745425 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 745425 non_coding RP11-206L10.8 . processed_transcript . . . 745425 non_coding RP11-206L10.9 . lincRNA . . . 745439 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 745439 non_coding RP11-206L10.8 . processed_transcript . . . 745439 non_coding RP11-206L10.9 . lincRNA . . . 745477 non_coding RP11-206L10.8 . transcribed_unprocessed_pseudogene . . . 745477 non_coding RP11-206L10.8 . processed_transcript . . . 745573 non_coding RP11-206L10.10 . processed_transcript . . . 745620 non_coding RP11-206L10.10 . processed_transcript . . . 745642 non_coding RP11-206L10.10 . processed_transcript . . . 753001 non_coding RP11-206L10.10 . processed_transcript . . . 753001 non_coding FAM87B . lincRNA . . . 753016 non_coding RP11-206L10.10 . processed_transcript . . . 753016 non_coding FAM87B . lincRNA . . . 753110 non_coding FAM87B . lincRNA . . . 808662 non_coding FAM41C . lincRNA . . . 808665 non_coding FAM41C . lincRNA . . . 808672 non_coding FAM41C . lincRNA . . . 808672 non_coding TUBB8P11 . unprocessed_pseudogene . . . 808695 non_coding FAM41C . lincRNA . . . 808695 non_coding TUBB8P11 . unprocessed_pseudogene . . . 808708 non_coding FAM41C . lincRNA . . . 808708 non_coding TUBB8P11 . unprocessed_pseudogene . . . 808710 non_coding FAM41C . lincRNA . . . 808710 non_coding TUBB8P11 . unprocessed_pseudogene . . . 808714 non_coding FAM41C . lincRNA . . . 808714 non_coding TUBB8P11 . unprocessed_pseudogene . . . 808723 non_coding FAM41C . lincRNA . . . 808723 non_coding TUBB8P11 . unprocessed_pseudogene . . . 809768 non_coding FAM41C . lincRNA . . . 860416 intron SAMD11 . protein_coding . . . 860417 intron SAMD11 . protein_coding . . . 860431 intron SAMD11 . protein_coding . . . 860461 intron SAMD11 . protein_coding . . . 860498 intron SAMD11 . protein_coding . . . 860504 intron SAMD11 . protein_coding . . . 860511 intron SAMD11 . protein_coding . . . 860521 intron SAMD11 . protein_coding . . . 860564 5_prime_utr SAMD11 ENST00000437963 protein_coding . . . 860604 intron SAMD11 . protein_coding . . . 860607 intron SAMD11 . protein_coding . . . 860637 intron SAMD11 . protein_coding . . . 860684 intron SAMD11 . protein_coding . . . 860688 intron SAMD11 . protein_coding . . . 861172 5_prime_utr SAMD11 ENST00000342066 protein_coding . . . 861177 5_prime_utr SAMD11 ENST00000342066 protein_coding . . . 861178 splice_region&5_prime_utr SAMD11 ENST00000342066 protein_coding . . . 861196 intron SAMD11 . protein_coding . . . 861209 intron SAMD11 . protein_coding . . . 861211 intron SAMD11 . protein_coding . . . 861213 intron SAMD11 . protein_coding . . . bcftools-1.21/test/split-vep.14.out000066400000000000000000000366271467060157400171560ustar00rootroot0000000000000014464 .,.,.,.,.,.,. 1,1,1,1,1,1,1 14469 .,.,.,.,.,.,. 1,1,1,1,1,1,1 14522 .,.,.,.,.,. 1,1,1,1,1,1 14542 .,.,.,.,.,. 1,1,1,1,1,1 14574 .,.,.,.,.,. 1,1,1,1,1,1 14590 .,.,.,.,.,. 1,1,1,1,1,1 14599 .,.,.,.,.,. 1,1,1,1,1,1 14653 .,.,.,.,.,. 1,1,1,1,1,1 14671 .,.,.,.,.,. 1,1,1,1,1,1 14673 .,.,.,.,.,. 1,1,1,1,1,1 14677 .,.,.,.,.,. 1,1,1,1,1,1 14696 .,.,.,.,.,. 1,1,1,1,1,1 14699 .,.,.,.,.,. 1,1,1,1,1,1 14729 .,.,.,.,.,. 1,1,1,1,1,1 14747 .,.,.,.,.,. 1,1,1,1,1,1 14763 .,.,.,.,.,. 1,1,1,1,1,1 14773 .,.,.,.,.,. 1,1,1,1,1,1 14815 .,.,.,.,.,. 1,1,1,1,1,1 14842 .,.,.,.,.,. 1,1,1,1,1,1 14843 .,.,.,.,.,. 1,1,1,1,1,1 14860 .,.,.,.,.,. 1,1,1,1,1,1 14863 .,.,.,.,.,. 1,1,1,1,1,1 14891 .,.,.,.,.,. 1,1,1,1,1,1 14896 .,.,.,.,.,. 1,1,1,1,1,1 14907 .,.,.,.,.,. 1,1,1,1,1,1 14908 .,.,.,.,.,. 1,1,1,1,1,1 14929 .,.,.,.,.,. 1,1,1,1,1,1 14930 .,.,.,.,.,. 1,1,1,1,1,1 14931 .,.,.,.,.,. 1,1,1,1,1,1 14933 .,.,.,.,.,. 1,1,1,1,1,1 14935 .,.,.,.,.,. 1,1,1,1,1,1 14936 .,.,.,.,.,. 1,1,1,1,1,1 14938 .,.,.,.,.,. 1,1,1,1,1,1 14947 .,.,.,.,.,. 1,1,1,1,1,1 14948 .,.,.,.,.,. 1,1,1,1,1,1 14949 .,.,.,.,.,. 1,1,1,1,1,1 14955 .,.,.,.,.,. 1,1,1,1,1,1 14956 .,.,.,.,.,. 1,1,1,1,1,1 14959 .,.,.,.,.,. 1,1,1,1,1,1 14961 .,.,.,.,.,. 1,1,1,1,1,1 14971 .,.,.,.,.,. 1,1,1,1,1,1 14974 .,.,.,.,.,. 1,1,1,1,1,1 14976 .,.,.,.,.,.,.,.,.,.,.,. 1,2,1,2,1,2,1,2,1,2,1,2 14978 .,.,.,.,.,. 1,1,1,1,1,1 15004 .,.,.,.,.,. 1,1,1,1,1,1 15029 .,.,.,.,.,. 1,1,1,1,1,1 15038 .,.,.,.,.,. 1,1,1,1,1,1 15058 .,.,.,.,.,. 1,1,1,1,1,1 15065 .,.,.,.,.,. 1,1,1,1,1,1 15072 .,.,.,.,.,. 1,1,1,1,1,1 15086 .,.,.,.,.,. 1,1,1,1,1,1 15112 .,.,.,.,.,. 1,1,1,1,1,1 15118 .,.,.,.,.,. 1,1,1,1,1,1 15688 .,.,.,.,.,.,. 1,1,1,1,1,1,1 15759 .,.,.,.,.,.,. 1,1,1,1,1,1,1 15773 .,.,.,.,.,.,. 1,1,1,1,1,1,1 15776 .,.,.,.,.,.,. 1,1,1,1,1,1,1 15777 .,.,.,.,.,.,. 1,1,1,1,1,1,1 15787 .,.,.,.,.,. 1,1,1,1,1,1 15811 .,.,.,.,.,. 1,1,1,1,1,1 15817 .,.,.,.,.,. 1,1,1,1,1,1 15820 .,.,.,.,.,. 1,1,1,1,1,1 15903 .,.,.,.,.,.,.,.,.,.,.,. 1,2,1,2,1,2,1,2,1,2,1,2 15906 .,.,.,.,.,. 1,1,1,1,1,1 15908 .,.,.,.,.,. 1,1,1,1,1,1 15912 .,.,.,.,.,. 1,1,1,1,1,1 15922 .,.,.,.,.,. 1,1,1,1,1,1 15974 .,.,.,.,.,. 1,1,1,1,1,1 15989 .,.,.,.,.,. 1,1,1,1,1,1 16014 .,.,.,.,.,. 1,1,1,1,1,1 16495 .,.,.,.,.,. 1,1,1,1,1,1 16497 .,.,.,.,.,. 1,1,1,1,1,1 16534 .,.,.,.,.,. 1,1,1,1,1,1 16571 .,.,.,.,.,. 1,1,1,1,1,1 16580 .,.,.,.,.,. 1,1,1,1,1,1 16682 .,.,.,.,.,. 1,1,1,1,1,1 16719 .,.,.,.,.,. 1,1,1,1,1,1 16792 .,.,.,.,.,. 1,1,1,1,1,1 16825 .,.,.,.,.,. 1,1,1,1,1,1 16841 .,.,.,.,.,. 1,1,1,1,1,1 16856 .,.,.,.,.,. 1,1,1,1,1,1 16957 .,.,.,.,.,. 1,1,1,1,1,1 16977 .,.,.,.,.,. 1,1,1,1,1,1 17020 .,.,.,.,.,. 1,1,1,1,1,1 17222 .,.,.,.,.,. 1,1,1,1,1,1 17289 .,.,.,.,.,. 1,1,1,1,1,1 17358 0.001388,0.001388,0.001388,0.001388,0.001388,0.001388 1,1,1,1,1,1 17365 .,.,.,.,.,. 1,1,1,1,1,1 17373 0.007138,0.007138,0.007138,0.007138,0.007138,0.007138 1,1,1,1,1,1 17375 0.01874,0.01874,0.01874,0.01874,0.01874,0.01874 1,1,1,1,1,1 17378 0,0,0,0,0,0 1,1,1,1,1,1 17379 0.003915,0.003915,0.003915,0.003915,0.003915,0.003915 1,1,1,1,1,1 17385 0.199,0.199,0.199,0.199,0.199,0.199 1,1,1,1,1,1 17398 0.000667,0.000667,0.000667,0.000667,0.000667,0.000667 1,1,1,1,1,1 17403 0.000963,0.000963,0.000963,0.000963,0.000963,0.000963 1,1,1,1,1,1 17406 0.003838,0.003838,0.003838,0.003838,0.003838,0.003838 1,1,1,1,1,1 17407 0.02517,0.02517,0.02517,0.02517,0.02517,0.02517 1,1,1,1,1,1 17408 0.008767,0.008767,0.008767,0.008767,0.008767,0.008767 1,1,1,1,1,1 17427 .,.,.,.,.,. 1,1,1,1,1,1 17444 .,.,.,.,.,. 1,1,1,1,1,1 17450 .,.,.,.,.,. 1,1,1,1,1,1 17452 0.02958,0.02958,0.02958,0.02958,0.02958,0.02958 1,1,1,1,1,1 17453 9.102e-05,9.102e-05,9.102e-05,9.102e-05,9.102e-05,9.102e-05 1,1,1,1,1,1 17455 .,.,.,.,.,. 1,1,1,1,1,1 17478 3.446e-05,3.446e-05,3.446e-05,3.446e-05,3.446e-05,3.446e-05 1,1,1,1,1,1 17479 5.135e-05,5.135e-05,5.135e-05,5.135e-05,5.135e-05,5.135e-05 1,1,1,1,1,1 17483 0.0001863,0.0001863,0.0001863,0.0001863,0.0001863,0.0001863 1,1,1,1,1,1 17484 0.0007271,0.0007271,0.0007271,0.0007271,0.0007271,0.0007271 1,1,1,1,1,1 17487 .,.,.,.,.,. 1,1,1,1,1,1 17490 .,.,.,.,.,. 1,1,1,1,1,1 17493 .,.,.,.,.,. 1,1,1,1,1,1 17501 .,.,.,.,.,. 1,1,1,1,1,1 17512 .,.,.,.,.,. 1,1,1,1,1,1 17516 .,.,.,.,.,. 1,1,1,1,1,1 17519 .,.,.,.,.,. 1,1,1,1,1,1 17527 .,.,.,.,.,. 1,1,1,1,1,1 17528 .,.,.,.,.,. 1,1,1,1,1,1 17538 .,.,.,.,.,. 1,1,1,1,1,1 17540 .,.,.,.,.,. 1,1,1,1,1,1 17556 .,.,.,.,.,. 1,1,1,1,1,1 17559 .,.,.,.,.,. 1,1,1,1,1,1 17562 .,.,.,.,.,. 1,1,1,1,1,1 17563 .,.,.,.,.,. 1,1,1,1,1,1 17585 .,.,.,.,.,. 1,1,1,1,1,1 17589 .,.,.,.,.,. 1,1,1,1,1,1 17594 .,.,.,.,.,. 1,1,1,1,1,1 17606 .,.,.,.,.,. 1,1,1,1,1,1 17614 .,.,.,.,.,. 1,1,1,1,1,1 17626 .,.,.,.,.,. 1,1,1,1,1,1 17636 .,.,.,.,.,. 1,1,1,1,1,1 17639 .,.,.,.,.,. 1,1,1,1,1,1 17645 .,.,.,.,.,. 1,1,1,1,1,1 17647 .,.,.,.,.,. 1,1,1,1,1,1 17652 .,.,.,.,.,. 1,1,1,1,1,1 17694 .,.,.,.,.,. 1,1,1,1,1,1 17695 .,.,.,.,.,. 1,1,1,1,1,1 17697 .,.,.,.,.,. 1,1,1,1,1,1 17701 .,.,.,.,.,. 1,1,1,1,1,1 17709 .,.,.,.,.,. 1,1,1,1,1,1 17716 .,.,.,.,.,. 1,1,1,1,1,1 17722 .,.,.,.,.,. 1,1,1,1,1,1 17728 .,.,.,.,.,. 1,1,1,1,1,1 17730 .,.,.,.,.,. 1,1,1,1,1,1 17746 .,.,.,.,.,. 1,1,1,1,1,1 17765 .,.,.,.,.,. 1,1,1,1,1,1 17805 .,.,.,.,.,. 1,1,1,1,1,1 17829 .,.,.,.,.,. 1,1,1,1,1,1 19190 .,.,.,.,.,. 1,1,1,1,1,1 19217 .,.,.,.,.,. 1,1,1,1,1,1 19226 .,.,.,.,.,. 1,1,1,1,1,1 19234 .,.,.,.,.,. 1,1,1,1,1,1 19236 .,.,.,.,.,. 1,1,1,1,1,1 19249 .,.,.,.,.,. 1,1,1,1,1,1 19254 .,.,.,.,.,. 1,1,1,1,1,1 62904 . 1 62905 . 1 62926 . 1 62950 . 1 62966 . 1 63093 . 1 63165 . 1 63210 . 1 63212 . 1 63307 . 1 63336 . 1 63415 . 1 63437 . 1 63458 . 1 63495 . 1 63516 . 1 63527 . 1 63528 . 1 63615 . 1 63627 . 1 63628 . 1 63642 . 1 63643 . 1 63654 . 1 63668 . 1 63671 . 1 63687 . 1 63697 . 1 63703 . 1 63708 . 1 63714 . 1 63717 . 1 63722 . 1 63735 . 1 63778 . 1 63791 . 1 65797 .,. 1,1 65843 .,. 1,1 65851 .,. 1,1 65864 .,. 1,1 65868 .,. 1,1 65872 .,. 1,1 65875 .,. 1,1 65892 .,. 1,1 65898 .,. 1,1 65900 .,. 1,1 65907 .,. 1,1 65910 .,. 1,1 65918 .,. 1,1 65973 .,. 1,1 65974 .,. 1,1 65975 .,. 1,1 65992 .,. 1,1 66026 .,. 1,1 66041 .,. 1,1 66042 .,.,.,. 1,2,1,2 66053 .,. 1,1 66055 .,. 1,1 69270 0.9112,0.9112 1,1 69428 0.04092,0.04092 1,1 69438 0.0002685,0.0002685 1,1 69453 5.667e-05,5.667e-05 1,1 69469 . 1 69486 5.737e-05 1 69489 0 1 69496 7.305e-05 1 69511 0.9728 1 69552 0 1 69559 0 1 69561 . 1 69569 0.0001266 1 69590 0 1 69594 2.823e-05 1 69604 . 1 69610 0 1 69634 1.603e-05 1 69640 0 1 69678 . 1 69690 . 1 69696 . 1 69713 9.731e-05 1 69719 . 1 69761 0.1558 1 69808 0 1 69816 0.0001677 1 69897 0.8442 1 120705 . 1 120745 . 1 120866 . 1 120871 . 1 120895 .,. 1,2 120961 . 1 120969 . 1 120983 . 1 120991 . 1 120994 . 1 120998 . 1 121009 . 1 121028 . 1 129077 . 1 129122 . 1 129148 .,. 1,2 129285 . 1 129301 . 1 129315 . 1 133355 .,.,.,. 1,1,1,1 133392 .,.,.,. 1,1,1,1 133477 .,.,.,. 1,1,1,1 133483 .,.,.,. 1,1,1,1 133558 .,.,.,. 1,1,1,1 135147 .,.,.,.,. 1,1,1,1,1 135151 .,.,.,.,. 1,1,1,1,1 135156 .,.,.,.,. 1,1,1,1,1 135162 .,.,.,.,. 1,1,1,1,1 135163 .,.,.,.,. 1,1,1,1,1 135172 .,.,.,.,. 1,1,1,1,1 135173 .,.,.,.,. 1,1,1,1,1 135178 .,.,.,.,. 1,1,1,1,1 135187 .,.,.,.,. 1,1,1,1,1 135193 .,.,.,.,. 1,1,1,1,1 135195 .,.,.,.,. 1,1,1,1,1 135196 .,.,.,.,. 1,1,1,1,1 135203 .,.,.,.,. 1,1,1,1,1 135215 .,.,.,.,. 1,1,1,1,1 135224 .,.,.,.,. 1,1,1,1,1 135232 .,.,.,.,. 1,1,1,1,1 135265 .,.,.,.,. 1,1,1,1,1 135297 .,.,.,.,. 1,1,1,1,1 135982 .,.,.,.,. 1,1,1,1,1 136041 .,.,.,.,. 1,1,1,1,1 136048 .,.,.,.,. 1,1,1,1,1 136060 .,.,.,.,. 1,1,1,1,1 136068 .,.,.,.,. 1,1,1,1,1 136073 .,.,.,.,. 1,1,1,1,1 136082 .,.,.,.,. 1,1,1,1,1 136113 .,.,.,.,.,. 1,1,1,1,1,1 136124 .,.,.,.,.,. 1,1,1,1,1,1 136210 .,.,.,.,.,. 1,1,1,1,1,1 137622 .,.,.,.,.,.,. 1,1,1,1,1,1,1 137825 .,.,.,.,.,.,. 1,1,1,1,1,1,1 267027 . 1 267069 . 1 267083 . 1 267099 . 1 267132 . 1 267147 . 1 267154 . 1 267216 . 1 267220 . 1 267226 . 1 267227 . 1 267229 . 2 267268 . 1 267276 . 1 267282 . 1 267289 . 1 267293 . 1 267294 . 1 267295 . 1 267300 . 2 267303 . 2 267305 .,. 2,3 267309 . 2 267310 . 2 267316 . 2 267319 . 2 267324 .,. 2,3 267331 . 2 267355 . 1 267359 . 2 647265 .,. 1,1 647380 . 1 647398 . 1 662029 .,. 1,1 662414 .,.,. 1,1,1 662531 .,.,. 1,1,1 662613 .,.,. 1,1,1 662622 .,.,. 1,1,1 662623 .,.,. 1,1,1 662843 .,.,. 1,1,1 662857 .,.,. 1,1,1 663083 .,.,. 1,1,1 663097 .,.,. 1,1,1 717379 .,. 1,1 717396 .,. 1,1 717432 .,. 1,1 717474 .,. 1,1 717481 .,. 1,1 717485 .,. 1,1 717486 .,.,.,. 1,2,1,2 717519 .,. 1,1 717534 .,. 1,1 717574 .,. 1,1 721256 . 1 721288 . 1 721290 . 1 721302 . 1 721303 . 1 721311 . 1 721323 . 1 721332 . 1 721361 . 1 721371 0.0001235 1 721409 . 1 721426 . 1 721439 . 1 721450 . 1 721462 . 1 721478 . 1 721538 0.001228 1 721540 . 1 721548 . 1 721549 . 1 721554 . 1 721566 9.695e-05 1 721569 . 1 721575 . 1 721576 . 1 721642 . 1 721645 5.883e-05 1 721668 1.986e-05 1 721682 . 1 721694 0.001185 1 721699 . 1 721705 0.0002371 1 721707 0 1 721708 . 1 721722 . 1 721724 1.979e-05 1 721735 0 1 721748 5.986e-05 1 721750 . 1 721757 0.04526 1 721772 . 1 721783 . 1 721788 0.0001046 1 721798 . 1 721806 0 1 721836 . 1 721847 0 1 721867 0.0001214 1 721873 0 1 721884 2.258e-05 1 721891 2.229e-05 1 721905 0 1 721915 . 1 721945 . 1 721948 . 1 721964 . 1 721977 . 1 721984 . 1 721994 . 1 721996 . 1 722025 .,. 1,2 722032 . 1 741163 .,.,. 1,1,1 741181 .,.,. 1,1,1 741235 .,.,. 1,1,1 741260 .,.,. 1,1,1 741267 .,.,. 1,1,1 741286 .,.,. 1,1,1 745347 .,. 1,1 745370 .,. 1,1 745425 .,. 1,1 745439 .,. 1,1 745477 .,. 1,1 745573 .,. 1,1 745620 .,. 1,1 745642 .,. 1,1 752737 .,.,. 1,1,1 752745 .,.,. 1,1,1 752748 .,.,. 1,1,1 752752 .,.,. 1,1,1 752770 .,.,. 1,1,1 752796 .,.,. 1,1,1 752802 .,.,. 1,1,1 752809 .,.,. 1,1,1 752841 .,.,. 1,1,1 752872 .,.,. 1,1,1 752873 .,.,. 1,1,1 752894 .,.,. 1,1,1 752915 .,.,. 1,1,1 752918 .,.,. 1,1,1 752938 .,.,. 1,1,1 752950 .,.,. 1,1,1 752996 .,.,. 1,1,1 753001 .,.,. 1,1,1 753016 .,.,. 1,1,1 753110 .,.,. 1,1,1 753168 .,.,. 1,1,1 753174 .,.,. 1,1,1 753185 .,.,. 1,1,1 753235 .,.,. 1,1,1 753263 .,.,. 1,1,1 753269 .,.,. 1,1,1 753291 .,.,. 1,1,1 753338 .,.,. 1,1,1 753405 .,.,. 1,1,1 753423 .,.,. 1,1,1 753424 .,.,. 1,1,1 753425 .,.,. 1,1,1 753426 .,.,. 1,1,1 753433 .,.,. 1,1,1 753444 .,.,. 1,1,1 753474 .,.,. 1,1,1 753479 .,.,. 1,1,1 762005 .,.,. 1,1,1 762008 .,.,. 1,1,1 762022 .,.,. 1,1,1 762031 .,.,. 1,1,1 762033 8.083e-05,8.083e-05,8.083e-05 1,1,1 762037 0.0003128,0.0003128,0.0003128 1,1,1 762038 .,.,. 1,1,1 762045 .,.,. 1,1,1 762052 .,.,. 1,1,1 762061 0.00942,0.00942,0.00942 1,1,1 762069 .,.,. 1,1,1 762070 5.963e-05,5.963e-05,5.963e-05 1,1,1 762085 .,.,. 1,1,1 762092 .,.,. 1,1,1 762109 0.02536,0.02536,0.02536 1,1,1 762142 0,0,0 1,1,1 762159 0.0003356,0.0003356,0.0003356 1,1,1 762175 0,0,0 1,1,1 762187 1.864e-05,1.864e-05,1.864e-05 1,1,1 762190 0,0,0 1,1,1 762199 0.0001119,0.0001119,0.0001119 1,1,1 762203 .,.,. 1,1,1 762211 .,.,. 1,1,1 762215 3.731e-05,3.731e-05,3.731e-05 1,1,1 762222 7.462e-05,7.462e-05,7.462e-05 1,1,1 762224 .,.,. 1,1,1 762249 1.866e-05,1.866e-05,1.866e-05 1,1,1 762262 .,.,. 1,1,1 762273 0.8606,0.8606,0.8606 1,1,1 762277 1.867e-05,1.867e-05,1.867e-05 1,1,1 762292 .,.,. 1,1,1 762307 5.599e-05,5.599e-05,5.599e-05 1,1,1 762320 0.001418,0.001418,0.001418 1,1,1 762330 0.003643,0.003643,0.003643 1,1,1 762339 .,.,. 1,1,1 762345 0.003937,0.003937,0.003937 1,1,1 762352 3.733e-05,3.733e-05,3.733e-05 1,1,1 762366 0.0001876,0.0001876,0.0001876 1,1,1 762383 .,.,. 1,1,1 762409 0.009415,0.009415,0.009415 1,1,1 762413 .,.,. 1,1,1 762418 .,.,. 1,1,1 762423 0,0,0 1,1,1 762426 .,.,. 1,1,1 762446 .,.,. 1,1,1 762449 .,.,. 1,1,1 762460 .,.,. 1,1,1 762465 .,.,. 1,1,1 762469 0,0,0 1,1,1 762472 0.08319,0.08319,0.08319 1,1,1 762475 .,.,. 1,1,1 762485 0.08856,0.08856,0.08856 1,1,1 762486 8.009e-05,8.009e-05,8.009e-05 1,1,1 762489 0,0,0 1,1,1 762494 6.181e-05,6.181e-05,6.181e-05 1,1,1 762523 0.001221,0.001221,0.001221 1,1,1 762538 3.25e-05,3.25e-05,3.25e-05 1,1,1 762588 0,0,0 1,1,1 762589 0.8575,0.8575,0.8575 1,1,1 762592 0.8581,0.8581,0.8581 1,1,1 762595 .,.,. 1,1,1 762601 0.8579,0.8579,0.8579 1,1,1 762604 .,.,. 1,1,1 762632 .,.,. 1,1,1 762637 .,.,. 1,1,1 777161 . 1 777175 . 1 777180 . 1 777183 . 1 777184 . 1 777189 . 1 777203 .,. 1,1 777232 .,. 1,1 777233 .,. 1,1 777237 .,. 1,1 777238 .,. 1,1 777242 .,. 1,1 777245 .,. 1,1 777256 .,. 1,1 777269 .,. 1,1 777288 .,. 1,1 777312 .,. 1,1 777317 .,. 1,1 777318 .,.,.,. 1,2,1,2 777348 .,. 1,1 777361 .,. 1,1 777379 .,. 1,1 777390 .,. 1,1 777392 .,. 1,1 777423 .,. 1,1 777431 .,. 1,1 777437 .,. 1,1 777444 .,. 1,1 777448 .,. 1,1 777449 .,. 1,1 777456 .,. 1,1 777459 .,. 1,1 777481 .,. 1,1 777498 .,. 1,1 777508 .,. 1,1 777512 .,. 1,1 777513 .,. 1,1 777516 .,. 1,1 777558 .,. 1,1 777564 .,. 1,1 777575 .,. 1,1 777578 .,. 1,1 777579 .,. 1,1 777581 .,. 1,1 777582 .,. 1,1 777588 .,. 1,1 777617 . 1 777636 . 1 777637 . 1 777654 . 1 777664 . 1 777670 . 1 777679 . 1 777683 . 1 777690 . 1 777699 . 1 777714 . 1 782980 . 1 782981 . 1 782982 . 1 783005 . 1 783015 . 1 783042 .,. 1,2 783049 . 1 783050 . 1 783060 . 1 783070 . 1 783071 . 1 783090 . 1 783095 . 1 783096 . 1 783101 . 1 783107 . 1 783124 .,. 1,2 783129 . 1 783142 . 1 783147 . 1 783150 . 1 783151 . 1 783174 . 1 783175 . 1 783180 . 1 783186 . 1 783193 . 1 783194 . 1 783209 . 1 783211 . 1 783226 . 1 783245 . 1 783249 . 1 792185 . 1 792194 . 1 792195 . 1 792207 . 1 792241 . 1 792254 . 1 792263 . 1 792264 . 1 792272 . 1 792276 . 1 792280 . 1 792288 . 1 792299 . 1 792300 . 1 792328 . 1 792346 .,. 1,2 792349 . 1 792355 . 1 792368 . 1 792373 . 1 792379 . 1 792392 . 1 792399 . 1 792405 . 1 792410 . 1 792423 . 1 792441 . 1 792443 . 1 792447 . 1 792448 . 1 792453 . 1 792480 . 1 792493 . 1 792496 . 1 792497 . 1 792506 . 1 792517 . 1 792523 . 1 792534 . 1 792537 . 1 792540 . 1 808659 .,. 1,1 808662 .,. 1,1 808665 .,. 1,1 808672 .,. 1,1 808695 .,. 1,1 808708 .,. 1,1 808710 .,. 1,1 808714 .,. 1,1 808723 .,. 1,1 808724 .,. 1,1 808725 .,. 1,1 808728 .,. 1,1 808729 .,. 1,1 808749 .,. 1,1 808756 .,. 1,1 808774 .,. 1,1 808788 .,. 1,1 808793 .,. 1,1 808816 .,. 1,1 808837 .,. 1,1 808845 .,. 1,1 808848 .,. 1,1 808861 .,. 1,1 808879 .,. 1,1 808888 .,. 1,1 808898 .,. 1,1 808899 .,. 1,1 808909 .,. 1,1 808922 .,. 1,1 808928 .,. 1,1 808929 .,. 1,1 808938 .,. 1,1 808957 .,. 1,1 808962 .,. 1,1 808984 .,. 1,1 808998 .,. 1,1 809001 .,. 1,1 809006 .,. 1,1 809007 .,. 1,1 809017 .,. 1,1 809022 .,. 1,1 809043 .,. 1,1 809091 .,. 1,1 809097 .,. 1,1 809107 .,. 1,1 809115 .,. 1,1 809116 .,. 1,1 809123 .,.,.,. 1,2,1,2 809136 .,. 1,1 809146 .,. 1,1 809150 .,. 1,1 809157 .,. 1,1 809171 .,. 1,1 809178 .,. 1,1 809213 .,. 1,1 809221 .,. 1,1 809237 .,. 1,1 809238 .,. 1,1 809242 .,. 1,1 809248 .,. 1,1 809261 .,. 1,1 809268 .,. 1,1 809273 .,. 1,1 809301 .,. 1,1 809319 .,. 1,1 809326 .,. 1,1 809329 .,. 1,1 809330 .,. 1,1 809346 .,. 1,1 809347 .,. 1,1 809351 .,. 1,1 809352 .,. 1,1 809353 .,. 1,1 809379 .,. 1,1 809385 .,. 1,1 809407 .,. 1,1 809427 .,. 1,1 809430 .,. 1,1 809434 .,. 1,1 809439 .,. 1,1 809446 .,. 1,1 809447 .,. 1,1 809451 .,. 1,1 809454 .,. 1,1 809464 .,. 1,1 809469 .,. 1,1 809470 .,. 1,1 809510 .,. 1,1 809533 .,. 1,1 809534 .,. 1,1 809535 .,. 1,1 809558 .,. 1,1 809563 .,. 1,1 809565 .,. 1,1 809572 .,. 1,1 809582 .,. 1,1 809590 .,. 1,1 809591 .,. 1,1 809594 .,. 1,1 809595 .,. 1,1 809596 .,. 1,1 809602 .,. 1,1 809615 .,. 1,1 809621 .,. 1,1 809622 .,. 1,1 809624 .,. 1,1 809628 .,. 1,1 809638 .,. 1,1 809680 .,. 1,1 809681 .,. 1,1 809687 .,.,.,. 1,2,1,2 809690 .,. 1,1 809700 .,. 1,1 809707 .,. 1,1 809711 .,. 1,1 809732 .,. 1,1 809741 .,. 1,1 809744 .,. 1,1 809752 .,.,.,. 1,2,1,2 809756 .,. 1,1 809761 .,. 1,1 809763 .,. 2,2 809764 .,. 1,1 809766 .,. 1,1 809768 .,. 1,1 860416 .,. 1,1 860417 .,. 1,1 860431 .,. 1,1 860461 .,. 1,1 860498 .,. 1,1 860504 .,. 1,1 860511 .,. 1,1 860521 .,. 1,1 860564 .,. 1,1 860604 .,. 1,1 860607 .,. 1,1 860637 .,. 1,1 860684 .,. 1,1 860688 .,. 1,1 861172 .,. 1,1 861177 .,. 1,1 861178 .,. 1,1 861196 .,. 1,1 861209 .,. 1,1 861211 .,. 1,1 861213 .,. 1,1 bcftools-1.21/test/split-vep.15.out000066400000000000000000000002351467060157400171410ustar00rootroot0000000000000069270 synonymous_variant 69428 . 69438 synonymous_variant 69453 synonymous_variant 69469 . 69486 synonymous_variant 69489 synonymous_variant 69496 . 69511 . bcftools-1.21/test/split-vep.16.out000066400000000000000000000001751467060157400171450ustar00rootroot0000000000000069270 synonymous_variant 69438 synonymous_variant 69453 synonymous_variant 69486 synonymous_variant 69489 synonymous_variant bcftools-1.21/test/split-vep.17.out000066400000000000000000000001241467060157400171400ustar00rootroot00000000000000##INFO= bcftools-1.21/test/split-vep.18.out000066400000000000000000000612521467060157400171520ustar00rootroot000000000000001 979496 . T C . . CSQ=C|missense_variant|MODERATE|PERM1|ENSG00000187642|Transcript|ENST00000341290|protein_coding|3/5||ENST00000341290.6:c.1192A>G|ENSP00000343864.2:p.Ser398Gly|1228|1192|398|S/G|Agc/Ggc|rs13302983||-1||SNV|HGNC|HGNC:28208|||2|A2||ENSP00000343864|Q5SV97||||tolerated(0.2)|benign(0.003)|PANTHER:PTHR47282&MobiDB_lite:mobidb-lite||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379407|protein_coding||||||||||rs13302983|4488|1||SNV|HGNC|HGNC:25284|||1|A2|CCDS53256.1|ENSP00000368717|Q494U1||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379409|protein_coding||||||||||rs13302983|4488|1||SNV|HGNC|HGNC:25284|||2|A2||ENSP00000368719|Q494U1||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379410|protein_coding||||||||||rs13302983|3631|1||SNV|HGNC|HGNC:25284|YES|NM_032129.3|1|P3|CCDS4.1|ENSP00000368720|Q494U1||UPI00001416D8||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|missense_variant|MODERATE|PERM1|ENSG00000187642|Transcript|ENST00000433179|protein_coding|1/3||ENST00000433179.3:c.1534A>G|ENSP00000414022.3:p.Ser512Gly|1534|1534|512|S/G|Agc/Ggc|rs13302983||-1||SNV|HGNC|HGNC:28208|YES||5|P2|CCDS76083.1|ENSP00000414022|Q5SV97||||tolerated(0.18)|benign(0.011)|PANTHER:PTHR47282&MobiDB_lite:mobidb-lite||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|upstream_gene_variant|MODIFIER|PERM1|ENSG00000187642|Transcript|ENST00000479361|retained_intron||||||||||rs13302983|2855|-1||SNV|HGNC|HGNC:28208|||1||||||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000491024|protein_coding||||||||||rs13302983|3631|1|cds_start_NF|SNV|HGNC|HGNC:25284|||3|||ENSP00000462558||J3KSM5|UPI000268AE1F||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1;Allele=C,C,C,C,C,C,C;Consequence=missense_variant,downstream_gene_variant,downstream_gene_variant,downstream_gene_variant,missense_variant,upstream_gene_variant,downstream_gene_variant;IMPACT=MODERATE,MODIFIER,MODIFIER,MODIFIER,MODERATE,MODIFIER,MODIFIER;SYMBOL=PERM1,PLEKHN1,PLEKHN1,PLEKHN1,PERM1,PERM1,PLEKHN1;Gene=ENSG00000187642,ENSG00000187583,ENSG00000187583,ENSG00000187583,ENSG00000187642,ENSG00000187642,ENSG00000187583;Feature_type=Transcript,Transcript,Transcript,Transcript,Transcript,Transcript,Transcript;Feature=ENST00000341290,ENST00000379407,ENST00000379409,ENST00000379410,ENST00000433179,ENST00000479361,ENST00000491024;BIOTYPE=protein_coding,protein_coding,protein_coding,protein_coding,protein_coding,retained_intron,protein_coding;EXON=3/5,.,.,.,1/3,.,.;INTRON=.,.,.,.,.,.,.;HGVSc=ENST00000341290.6:c.1192A>G,.,.,.,ENST00000433179.3:c.1534A>G,.,.;HGVSp=ENSP00000343864.2:p.Ser398Gly,.,.,.,ENSP00000414022.3:p.Ser512Gly,.,.;cDNA_position=1228,.,.,.,1534,.,.;CDS_position=1192,.,.,.,1534,.,.;Protein_position=398,.,.,.,512,.,.;Amino_acids=S/G,.,.,.,S/G,.,.;Codons=Agc/Ggc,.,.,.,Agc/Ggc,.,.;Existing_variation=rs13302983,rs13302983,rs13302983,rs13302983,rs13302983,rs13302983,rs13302983;DISTANCE=.,4488,4488,3631,.,2855,3631;STRAND=-1,1,1,1,-1,-1,1;FLAGS=.,.,.,.,.,.,cds_start_NF;VARIANT_CLASS=SNV,SNV,SNV,SNV,SNV,SNV,SNV;SYMBOL_SOURCE=HGNC,HGNC,HGNC,HGNC,HGNC,HGNC,HGNC;HGNC_ID=HGNC:28208,HGNC:25284,HGNC:25284,HGNC:25284,HGNC:28208,HGNC:28208,HGNC:25284;CANONICAL=.,.,.,YES,YES,.,.;MANE=.,.,.,NM_032129.3,.,.,.;TSL=2,1,2,1,5,1,3;APPRIS=A2,A2,A2,P3,P2,.,.;CCDS=.,CCDS53256.1,.,CCDS4.1,CCDS76083.1,.,.;ENSP=ENSP00000343864,ENSP00000368717,ENSP00000368719,ENSP00000368720,ENSP00000414022,.,ENSP00000462558;SWISSPROT=Q5SV97,Q494U1,Q494U1,Q494U1,Q5SV97,.,.;TREMBL=.,.,.,.,.,.,J3KSM5;UNIPARC=.,.,.,UPI00001416D8,.,.,UPI000268AE1F;GENE_PHENO=.,.,.,.,.,.,.;SIFT=tolerated(0.2),.,.,.,tolerated(0.18),.,.;PolyPhen=benign(0.003),.,.,.,benign(0.011),.,.;DOMAINS=PANTHER:PTHR47282&MobiDB_lite:mobidb-lite,.,.,.,PANTHER:PTHR47282&MobiDB_lite:mobidb-lite,.,.;miRNA=.,.,.,.,.,.,.;HGVS_OFFSET=.,.,.,.,.,.,.;AF=.,.,.,.,.,.,.;AFR_AF=0.9418,0.9418,0.9418,0.9418,0.9418,0.9418,0.9418;AMR_AF=0.9539,0.9539,0.9539,0.9539,0.9539,0.9539,0.9539;EAS_AF=0.999,0.999,0.999,0.999,0.999,0.999,0.999;EUR_AF=0.9592,0.9592,0.9592,0.9592,0.9592,0.9592,0.9592;SAS_AF=0.9847,0.9847,0.9847,0.9847,0.9847,0.9847,0.9847;AA_AF=.,.,.,.,.,.,.;EA_AF=.,.,.,.,.,.,.;gnomAD_AF=0.9721,0.9721,0.9721,0.9721,0.9721,0.9721,0.9721;gnomAD_AFR_AF=0.9533,0.9533,0.9533,0.9533,0.9533,0.9533,0.9533;gnomAD_AMR_AF=0.9754,0.9754,0.9754,0.9754,0.9754,0.9754,0.9754;gnomAD_ASJ_AF=0.9166,0.9166,0.9166,0.9166,0.9166,0.9166,0.9166;gnomAD_EAS_AF=0.9999,0.9999,0.9999,0.9999,0.9999,0.9999,0.9999;gnomAD_FIN_AF=0.9923,0.9923,0.9923,0.9923,0.9923,0.9923,0.9923;gnomAD_NFE_AF=0.9677,0.9677,0.9677,0.9677,0.9677,0.9677,0.9677;gnomAD_OTH_AF=0.9536,0.9536,0.9536,0.9536,0.9536,0.9536,0.9536;gnomAD_SAS_AF=0.9811,0.9811,0.9811,0.9811,0.9811,0.9811,0.9811;MAX_AF=0.9999,0.9999,0.9999,0.9999,0.9999,0.9999,0.9999;MAX_AF_POPS=gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS;CLIN_SIG=.,.,.,.,.,.,.;SOMATIC=.,.,.,.,.,.,.;PHENO=.,.,.,.,.,.,.;PUBMED=.,.,.,.,.,.,.;MOTIF_NAME=.,.,.,.,.,.,.;MOTIF_POS=.,.,.,.,.,.,.;HIGH_INF_POS=.,.,.,.,.,.,.;MOTIF_SCORE_CHANGE=.,.,.,.,.,.,.;existing_InFrame_oORFs=.,.,.,.,.,.,.;existing_OutOfFrame_oORFs=.,.,.,.,.,.,.;existing_uORFs=.,.,.,.,.,.,.;five_prime_UTR_variant_annotation=.,.,.,.,.,.,.;five_prime_UTR_variant_consequence=.,.,.,.,.,.,.;SpliceRegion=.,.,.,.,.,.,.;LoF=.,.,.,.,.,.,.;LoF_filter=.,.,.,.,.,.,.;LoF_flags=.,.,.,.,.,.,.;LoF_info=.,.,.,.,.,.,.;SpliceAI_pred_DP_AG=-27,-27,-27,-27,-27,-27,-27;SpliceAI_pred_DP_AL=-2,-2,-2,-2,-2,-2,-2;SpliceAI_pred_DP_DG=23,23,23,23,23,23,23;SpliceAI_pred_DP_DL=25,25,25,25,25,25,25;SpliceAI_pred_DS_AG=0,0,0,0,0,0,0;SpliceAI_pred_DS_AL=0,0,0,0,0,0,0;SpliceAI_pred_DS_DG=0,0,0,0,0,0,0;SpliceAI_pred_DS_DL=0,0,0,0,0,0,0;SpliceAI_pred_SYMBOL=PERM1,PERM1,PERM1,PERM1,PERM1,PERM1,PERM1 1 979560 . T C . . CSQ=C|synonymous_variant|LOW|PERM1|ENSG00000187642|Transcript|ENST00000341290|protein_coding|3/5||ENST00000341290.6:c.1128A>G|ENSP00000343864.2:p.Ala376%3D|1164|1128|376|A|gcA/gcG|rs13303033||-1||SNV|HGNC|HGNC:28208|||2|A2||ENSP00000343864|Q5SV97||||||PANTHER:PTHR47282&Low_complexity_(Seg):seg|||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379407|protein_coding||||||||||rs13303033|4552|1||SNV|HGNC|HGNC:25284|||1|A2|CCDS53256.1|ENSP00000368717|Q494U1|||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379409|protein_coding||||||||||rs13303033|4552|1||SNV|HGNC|HGNC:25284|||2|A2||ENSP00000368719|Q494U1|||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379410|protein_coding||||||||||rs13303033|3695|1||SNV|HGNC|HGNC:25284|YES|NM_032129.3|1|P3|CCDS4.1|ENSP00000368720|Q494U1||UPI00001416D8|||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|synonymous_variant|LOW|PERM1|ENSG00000187642|Transcript|ENST00000433179|protein_coding|1/3||ENST00000433179.3:c.1470A>G|ENSP00000414022.3:p.Ala490%3D|1470|1470|490|A|gcA/gcG|rs13303033||-1||SNV|HGNC|HGNC:28208|YES||5|P2|CCDS76083.1|ENSP00000414022|Q5SV97||||||PANTHER:PTHR47282&Low_complexity_(Seg):seg|||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|upstream_gene_variant|MODIFIER|PERM1|ENSG00000187642|Transcript|ENST00000479361|retained_intron||||||||||rs13303033|2919|-1||SNV|HGNC|HGNC:28208|||1|||||||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000491024|protein_coding||||||||||rs13303033|3695|1|cds_start_NF|SNV|HGNC|HGNC:25284|||3|||ENSP00000462558||J3KSM5|UPI000268AE1F|||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1;Allele=C,C,C,C,C,C,C;Consequence=synonymous_variant,downstream_gene_variant,downstream_gene_variant,downstream_gene_variant,synonymous_variant,upstream_gene_variant,downstream_gene_variant;IMPACT=LOW,MODIFIER,MODIFIER,MODIFIER,LOW,MODIFIER,MODIFIER;SYMBOL=PERM1,PLEKHN1,PLEKHN1,PLEKHN1,PERM1,PERM1,PLEKHN1;Gene=ENSG00000187642,ENSG00000187583,ENSG00000187583,ENSG00000187583,ENSG00000187642,ENSG00000187642,ENSG00000187583;Feature_type=Transcript,Transcript,Transcript,Transcript,Transcript,Transcript,Transcript;Feature=ENST00000341290,ENST00000379407,ENST00000379409,ENST00000379410,ENST00000433179,ENST00000479361,ENST00000491024;BIOTYPE=protein_coding,protein_coding,protein_coding,protein_coding,protein_coding,retained_intron,protein_coding;EXON=3/5,.,.,.,1/3,.,.;INTRON=.,.,.,.,.,.,.;HGVSc=ENST00000341290.6:c.1128A>G,.,.,.,ENST00000433179.3:c.1470A>G,.,.;HGVSp=ENSP00000343864.2:p.Ala376%3D,.,.,.,ENSP00000414022.3:p.Ala490%3D,.,.;cDNA_position=1164,.,.,.,1470,.,.;CDS_position=1128,.,.,.,1470,.,.;Protein_position=376,.,.,.,490,.,.;Amino_acids=A,.,.,.,A,.,.;Codons=gcA/gcG,.,.,.,gcA/gcG,.,.;Existing_variation=rs13303033,rs13303033,rs13303033,rs13303033,rs13303033,rs13303033,rs13303033;DISTANCE=.,4552,4552,3695,.,2919,3695;STRAND=-1,1,1,1,-1,-1,1;FLAGS=.,.,.,.,.,.,cds_start_NF;VARIANT_CLASS=SNV,SNV,SNV,SNV,SNV,SNV,SNV;SYMBOL_SOURCE=HGNC,HGNC,HGNC,HGNC,HGNC,HGNC,HGNC;HGNC_ID=HGNC:28208,HGNC:25284,HGNC:25284,HGNC:25284,HGNC:28208,HGNC:28208,HGNC:25284;CANONICAL=.,.,.,YES,YES,.,.;MANE=.,.,.,NM_032129.3,.,.,.;TSL=2,1,2,1,5,1,3;APPRIS=A2,A2,A2,P3,P2,.,.;CCDS=.,CCDS53256.1,.,CCDS4.1,CCDS76083.1,.,.;ENSP=ENSP00000343864,ENSP00000368717,ENSP00000368719,ENSP00000368720,ENSP00000414022,.,ENSP00000462558;SWISSPROT=Q5SV97,Q494U1,Q494U1,Q494U1,Q5SV97,.,.;TREMBL=.,.,.,.,.,.,J3KSM5;UNIPARC=.,.,.,UPI00001416D8,.,.,UPI000268AE1F;GENE_PHENO=.,.,.,.,.,.,.;SIFT=.,.,.,.,.,.,.;PolyPhen=.,.,.,.,.,.,.;DOMAINS=PANTHER:PTHR47282&Low_complexity_(Seg):seg,.,.,.,PANTHER:PTHR47282&Low_complexity_(Seg):seg,.,.;miRNA=.,.,.,.,.,.,.;HGVS_OFFSET=.,.,.,.,.,.,.;AF=0.5096,0.5096,0.5096,0.5096,0.5096,0.5096,0.5096;AFR_AF=0.177,0.177,0.177,0.177,0.177,0.177,0.177;AMR_AF=0.6095,0.6095,0.6095,0.6095,0.6095,0.6095,0.6095;EAS_AF=0.7123,0.7123,0.7123,0.7123,0.7123,0.7123,0.7123;EUR_AF=0.5895,0.5895,0.5895,0.5895,0.5895,0.5895,0.5895;SAS_AF=0.5971,0.5971,0.5971,0.5971,0.5971,0.5971,0.5971;AA_AF=.,.,.,.,.,.,.;EA_AF=.,.,.,.,.,.,.;gnomAD_AF=0.5887,0.5887,0.5887,0.5887,0.5887,0.5887,0.5887;gnomAD_AFR_AF=0.2428,0.2428,0.2428,0.2428,0.2428,0.2428,0.2428;gnomAD_AMR_AF=0.6604,0.6604,0.6604,0.6604,0.6604,0.6604,0.6604;gnomAD_ASJ_AF=0.5617,0.5617,0.5617,0.5617,0.5617,0.5617,0.5617;gnomAD_EAS_AF=0.7237,0.7237,0.7237,0.7237,0.7237,0.7237,0.7237;gnomAD_FIN_AF=0.5334,0.5334,0.5334,0.5334,0.5334,0.5334,0.5334;gnomAD_NFE_AF=0.5801,0.5801,0.5801,0.5801,0.5801,0.5801,0.5801;gnomAD_OTH_AF=0.5647,0.5647,0.5647,0.5647,0.5647,0.5647,0.5647;gnomAD_SAS_AF=0.6213,0.6213,0.6213,0.6213,0.6213,0.6213,0.6213;MAX_AF=0.7237,0.7237,0.7237,0.7237,0.7237,0.7237,0.7237;MAX_AF_POPS=gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS;CLIN_SIG=.,.,.,.,.,.,.;SOMATIC=.,.,.,.,.,.,.;PHENO=.,.,.,.,.,.,.;PUBMED=.,.,.,.,.,.,.;MOTIF_NAME=.,.,.,.,.,.,.;MOTIF_POS=.,.,.,.,.,.,.;HIGH_INF_POS=.,.,.,.,.,.,.;MOTIF_SCORE_CHANGE=.,.,.,.,.,.,.;existing_InFrame_oORFs=.,.,.,.,.,.,.;existing_OutOfFrame_oORFs=.,.,.,.,.,.,.;existing_uORFs=.,.,.,.,.,.,.;five_prime_UTR_variant_annotation=.,.,.,.,.,.,.;five_prime_UTR_variant_consequence=.,.,.,.,.,.,.;SpliceRegion=.,.,.,.,.,.,.;LoF=.,.,.,.,.,.,.;LoF_filter=.,.,.,.,.,.,.;LoF_flags=.,.,.,.,.,.,.;LoF_info=.,.,.,.,.,.,.;SpliceAI_pred_DP_AG=28,28,28,28,28,28,28;SpliceAI_pred_DP_AL=-30,-30,-30,-30,-30,-30,-30;SpliceAI_pred_DP_DG=-39,-39,-39,-39,-39,-39,-39;SpliceAI_pred_DP_DL=3,3,3,3,3,3,3;SpliceAI_pred_DS_AG=0,0,0,0,0,0,0;SpliceAI_pred_DS_AL=0,0,0,0,0,0,0;SpliceAI_pred_DS_DG=0,0,0,0,0,0,0;SpliceAI_pred_DS_DL=0,0,0,0,0,0,0;SpliceAI_pred_SYMBOL=PERM1,PERM1,PERM1,PERM1,PERM1,PERM1,PERM1 1 999842 . C A . . CSQ=A|intron_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000304952|protein_coding||1/3|ENST00000304952.11:c.108+24G>T|||||||rs2298214||-1||SNV|HGNC|HGNC:24149||NM_021170.4|1|P1|CCDS5.1|ENSP00000304595|Q9HCC6|||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|missense_variant|MODERATE|HES4|ENSG00000188290|Transcript|ENST00000428771|protein_coding|1/3||ENST00000428771.6:c.132G>T|ENSP00000393198.2:p.Arg44Ser|331|132|44|R/S|agG/agT|rs2298214||-1||SNV|HGNC|HGNC:24149|YES||2||CCDS44034.1|ENSP00000393198||E9PB28|UPI0001881B51||tolerated_low_confidence(0.72)|benign(0)|MobiDB_lite:mobidb-lite&Low_complexity_(Seg):seg|||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS||||||||||||||||||MUTANT_DONOR_MES:11.0784944978449&EXON_END:1000172&INTRON_END:999691&DE_NOVO_DONOR_MES_POS:-156&DE_NOVO_DONOR_POS:-156&EXON_START:999692&DE_NOVO_DONOR_MES:7.0006176073036&DE_NOVO_DONOR_PROB:0.167156964545091&INTRON_START:999614|6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|non_coding_transcript_exon_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000481869|retained_intron|1/2||ENST00000481869.1:n.255G>T||255|||||rs2298214||-1||SNV|HGNC|HGNC:24149|||2|||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|intron_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000484667|protein_coding||1/2|ENST00000484667.2:c.108+24G>T|||||||rs2298214||-1||SNV|HGNC|HGNC:24149|||3|||ENSP00000425085||D6REB3|UPI0001D3BBEE|||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|AL645608.7|ENSG00000272512|Transcript|ENST00000606034|lncRNA||||||||||rs2298214|1791|-1||SNV|Clone_based_ensembl_gene||YES|||||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|ISG15|ENSG00000187608|Transcript|ENST00000624652|protein_coding||||||||||rs2298214|1303|1|cds_end_NF|SNV|HGNC|HGNC:4053|||3|||ENSP00000485313||A0A096LNZ9||1||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|ISG15|ENSG00000187608|Transcript|ENST00000624697|protein_coding||||||||||rs2298214|1296|1||SNV|HGNC|HGNC:4053|||3|A2||ENSP00000485643||A0A096LPJ4||1||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000118|promoter||||||||||rs2298214||||SNV||||||||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||||||||||;Allele=A,A,A,A,A,A,A,A;Consequence=intron_variant,missense_variant,non_coding_transcript_exon_variant,intron_variant,upstream_gene_variant,upstream_gene_variant,upstream_gene_variant,regulatory_region_variant;IMPACT=MODIFIER,MODERATE,MODIFIER,MODIFIER,MODIFIER,MODIFIER,MODIFIER,MODIFIER;SYMBOL=HES4,HES4,HES4,HES4,AL645608.7,ISG15,ISG15,.;Gene=ENSG00000188290,ENSG00000188290,ENSG00000188290,ENSG00000188290,ENSG00000272512,ENSG00000187608,ENSG00000187608,.;Feature_type=Transcript,Transcript,Transcript,Transcript,Transcript,Transcript,Transcript,RegulatoryFeature;Feature=ENST00000304952,ENST00000428771,ENST00000481869,ENST00000484667,ENST00000606034,ENST00000624652,ENST00000624697,ENSR00000000118;BIOTYPE=protein_coding,protein_coding,retained_intron,protein_coding,lncRNA,protein_coding,protein_coding,promoter;EXON=.,1/3,1/2,.,.,.,.,.;INTRON=1/3,.,.,1/2,.,.,.,.;HGVSc=ENST00000304952.11:c.108+24G>T,ENST00000428771.6:c.132G>T,ENST00000481869.1:n.255G>T,ENST00000484667.2:c.108+24G>T,.,.,.,.;HGVSp=.,ENSP00000393198.2:p.Arg44Ser,.,.,.,.,.,.;cDNA_position=.,331,255,.,.,.,.,.;CDS_position=.,132,.,.,.,.,.,.;Protein_position=.,44,.,.,.,.,.,.;Amino_acids=.,R/S,.,.,.,.,.,.;Codons=.,agG/agT,.,.,.,.,.,.;Existing_variation=rs2298214,rs2298214,rs2298214,rs2298214,rs2298214,rs2298214,rs2298214,rs2298214;DISTANCE=.,.,.,.,1791,1303,1296,.;STRAND=-1,-1,-1,-1,-1,1,1,.;FLAGS=.,.,.,.,.,cds_end_NF,.,.;VARIANT_CLASS=SNV,SNV,SNV,SNV,SNV,SNV,SNV,SNV;SYMBOL_SOURCE=HGNC,HGNC,HGNC,HGNC,Clone_based_ensembl_gene,HGNC,HGNC,.;HGNC_ID=HGNC:24149,HGNC:24149,HGNC:24149,HGNC:24149,.,HGNC:4053,HGNC:4053,.;CANONICAL=.,YES,.,.,YES,.,.,.;MANE=NM_021170.4,.,.,.,.,.,.,.;TSL=1,2,2,3,.,3,3,.;APPRIS=P1,.,.,.,.,.,A2,.;CCDS=CCDS5.1,CCDS44034.1,.,.,.,.,.,.;ENSP=ENSP00000304595,ENSP00000393198,.,ENSP00000425085,.,ENSP00000485313,ENSP00000485643,.;SWISSPROT=Q9HCC6,.,.,.,.,.,.,.;TREMBL=.,E9PB28,.,D6REB3,.,A0A096LNZ9,A0A096LPJ4,.;UNIPARC=.,UPI0001881B51,.,UPI0001D3BBEE,.,.,.,.;GENE_PHENO=.,.,.,.,.,1,1,.;SIFT=.,tolerated_low_confidence(0.72),.,.,.,.,.,.;PolyPhen=.,benign(0),.,.,.,.,.,.;DOMAINS=.,MobiDB_lite:mobidb-lite&Low_complexity_(Seg):seg,.,.,.,.,.,.;miRNA=.,.,.,.,.,.,.,.;HGVS_OFFSET=.,.,.,.,.,.,.,.;AF=0.4938,0.4938,0.4938,0.4938,0.4938,0.4938,0.4938,0.4938;AFR_AF=0.0356,0.0356,0.0356,0.0356,0.0356,0.0356,0.0356,0.0356;AMR_AF=0.6268,0.6268,0.6268,0.6268,0.6268,0.6268,0.6268,0.6268;EAS_AF=0.7718,0.7718,0.7718,0.7718,0.7718,0.7718,0.7718,0.7718;EUR_AF=0.5895,0.5895,0.5895,0.5895,0.5895,0.5895,0.5895,0.5895;SAS_AF=0.6339,0.6339,0.6339,0.6339,0.6339,0.6339,0.6339,0.6339;AA_AF=0.1386,0.1386,0.1386,0.1386,0.1386,0.1386,0.1386,0.1386;EA_AF=0.5695,0.5695,0.5695,0.5695,0.5695,0.5695,0.5695,0.5695;gnomAD_AF=0.6136,0.6136,0.6136,0.6136,0.6136,0.6136,0.6136,0.6136;gnomAD_AFR_AF=0.1208,0.1208,0.1208,0.1208,0.1208,0.1208,0.1208,0.1208;gnomAD_AMR_AF=0.7139,0.7139,0.7139,0.7139,0.7139,0.7139,0.7139,0.7139;gnomAD_ASJ_AF=0.6344,0.6344,0.6344,0.6344,0.6344,0.6344,0.6344,0.6344;gnomAD_EAS_AF=0.786,0.786,0.786,0.786,0.786,0.786,0.786,0.786;gnomAD_FIN_AF=0.5555,0.5555,0.5555,0.5555,0.5555,0.5555,0.5555,0.5555;gnomAD_NFE_AF=0.595,0.595,0.595,0.595,0.595,0.595,0.595,0.595;gnomAD_OTH_AF=0.5882,0.5882,0.5882,0.5882,0.5882,0.5882,0.5882,0.5882;gnomAD_SAS_AF=0.6625,0.6625,0.6625,0.6625,0.6625,0.6625,0.6625,0.6625;MAX_AF=0.786,0.786,0.786,0.786,0.786,0.786,0.786,0.786;MAX_AF_POPS=gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS,gnomAD_EAS;CLIN_SIG=.,.,.,.,.,.,.,.;SOMATIC=.,.,.,.,.,.,.,.;PHENO=.,.,.,.,.,.,.,.;PUBMED=.,.,.,.,.,.,.,.;MOTIF_NAME=.,.,.,.,.,.,.,.;MOTIF_POS=.,.,.,.,.,.,.,.;HIGH_INF_POS=.,.,.,.,.,.,.,.;MOTIF_SCORE_CHANGE=.,.,.,.,.,.,.,.;existing_InFrame_oORFs=.,.,.,.,.,.,.,.;existing_OutOfFrame_oORFs=.,.,.,.,.,.,.,.;existing_uORFs=.,.,.,.,.,.,.,.;five_prime_UTR_variant_annotation=.,.,.,.,.,.,.,.;five_prime_UTR_variant_consequence=.,.,.,.,.,.,.,.;SpliceRegion=.,.,.,.,.,.,.,.;LoF=.,.,.,.,.,.,.,.;LoF_filter=.,.,.,.,.,.,.,.;LoF_flags=.,.,.,.,.,.,.,.;LoF_info=.,MUTANT_DONOR_MES:11.0784944978449&EXON_END:1000172&INTRON_END:999691&DE_NOVO_DONOR_MES_POS:-156&DE_NOVO_DONOR_POS:-156&EXON_START:999692&DE_NOVO_DONOR_MES:7.0006176073036&DE_NOVO_DONOR_PROB:0.167156964545091&INTRON_START:999614,.,.,.,.,.,.;SpliceAI_pred_DP_AG=6,6,6,6,6,6,6,.;SpliceAI_pred_DP_AL=-37,-37,-37,-37,-37,-37,-37,.;SpliceAI_pred_DP_DG=6,6,6,6,6,6,6,.;SpliceAI_pred_DP_DL=24,24,24,24,24,24,24,.;SpliceAI_pred_DS_AG=0,0,0,0,0,0,0,.;SpliceAI_pred_DS_AL=0,0,0,0,0,0,0,.;SpliceAI_pred_DS_DG=0.01,0.01,0.01,0.01,0.01,0.01,0.01,.;SpliceAI_pred_DS_DL=0.02,0.02,0.02,0.02,0.02,0.02,0.02,.;SpliceAI_pred_SYMBOL=HES4,HES4,HES4,HES4,HES4,HES4,HES4,. 1 12716215 . C A . . CSQ=A|stop_gained|HIGH|AADACL3|ENSG00000188984|Transcript|ENST00000359318|protein_coding|1/4||ENST00000359318.8:c.39C>A|ENSP00000352268.6:p.Cys13Ter|106|39|13|C/*|tgC/tgA|rs3000860||1||SNV|HGNC|HGNC:32037|YES|NM_001103170.3|3|P1|CCDS41253.2|ENSP00000352268|Q5VUY0||UPI0003EAEC70||||PIRSF:PIRSF037251&PANTHER:PTHR23024&PANTHER:PTHR23024:SF115&Transmembrane_helices:TMhelix|||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||HC|||GERP_DIST:92.57575&BP_DIST:1182&PERCENTILE:0.0318627450980392&DIST_FROM_LAST_EXON:408&50_BP_RULE:PASS&PHYLOCSF_TOO_SHORT|||||||||,A|non_coding_transcript_exon_variant|MODIFIER|AADACL3|ENSG00000188984|Transcript|ENST00000620146|processed_transcript|1/3||ENST00000620146.2:n.101C>A||101|||||rs3000860||1||SNV|HGNC|HGNC:32037|||2|||||||||||||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000347677|promoter_flanking_region||||||||||rs3000860||||SNV||||||||||||||||||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||||||||||||||;Allele=A,A,A;Consequence=stop_gained,non_coding_transcript_exon_variant,regulatory_region_variant;IMPACT=HIGH,MODIFIER,MODIFIER;SYMBOL=AADACL3,AADACL3,.;Gene=ENSG00000188984,ENSG00000188984,.;Feature_type=Transcript,Transcript,RegulatoryFeature;Feature=ENST00000359318,ENST00000620146,ENSR00000347677;BIOTYPE=protein_coding,processed_transcript,promoter_flanking_region;EXON=1/4,1/3,.;INTRON=.,.,.;HGVSc=ENST00000359318.8:c.39C>A,ENST00000620146.2:n.101C>A,.;HGVSp=ENSP00000352268.6:p.Cys13Ter,.,.;cDNA_position=106,101,.;CDS_position=39,.,.;Protein_position=13,.,.;Amino_acids=C/*,.,.;Codons=tgC/tgA,.,.;Existing_variation=rs3000860,rs3000860,rs3000860;DISTANCE=.,.,.;STRAND=1,1,.;FLAGS=.,.,.;VARIANT_CLASS=SNV,SNV,SNV;SYMBOL_SOURCE=HGNC,HGNC,.;HGNC_ID=HGNC:32037,HGNC:32037,.;CANONICAL=YES,.,.;MANE=NM_001103170.3,.,.;TSL=3,2,.;APPRIS=P1,.,.;CCDS=CCDS41253.2,.,.;ENSP=ENSP00000352268,.,.;SWISSPROT=Q5VUY0,.,.;TREMBL=.,.,.;UNIPARC=UPI0003EAEC70,.,.;GENE_PHENO=.,.,.;SIFT=.,.,.;PolyPhen=.,.,.;DOMAINS=PIRSF:PIRSF037251&PANTHER:PTHR23024&PANTHER:PTHR23024:SF115&Transmembrane_helices:TMhelix,.,.;miRNA=.,.,.;HGVS_OFFSET=.,.,.;AF=0.1436,0.1436,0.1436;AFR_AF=0.1188,0.1188,0.1188;AMR_AF=0.1052,0.1052,0.1052;EAS_AF=0.2679,0.2679,0.2679;EUR_AF=0.1362,0.1362,0.1362;SAS_AF=0.0838,0.0838,0.0838;AA_AF=.,.,.;EA_AF=.,.,.;gnomAD_AF=.,.,.;gnomAD_AFR_AF=.,.,.;gnomAD_AMR_AF=.,.,.;gnomAD_ASJ_AF=.,.,.;gnomAD_EAS_AF=.,.,.;gnomAD_FIN_AF=.,.,.;gnomAD_NFE_AF=.,.,.;gnomAD_OTH_AF=.,.,.;gnomAD_SAS_AF=.,.,.;MAX_AF=0.2679,0.2679,0.2679;MAX_AF_POPS=EAS,EAS,EAS;CLIN_SIG=.,.,.;SOMATIC=.,.,.;PHENO=.,.,.;PUBMED=.,.,.;MOTIF_NAME=.,.,.;MOTIF_POS=.,.,.;HIGH_INF_POS=.,.,.;MOTIF_SCORE_CHANGE=.,.,.;existing_InFrame_oORFs=.,.,.;existing_OutOfFrame_oORFs=.,.,.;existing_uORFs=.,.,.;five_prime_UTR_variant_annotation=.,.,.;five_prime_UTR_variant_consequence=.,.,.;SpliceRegion=.,.,.;LoF=HC,.,.;LoF_filter=.,.,.;LoF_flags=.,.,.;LoF_info=GERP_DIST:92.57575&BP_DIST:1182&PERCENTILE:0.0318627450980392&DIST_FROM_LAST_EXON:408&50_BP_RULE:PASS&PHYLOCSF_TOO_SHORT,.,.;SpliceAI_pred_DP_AG=.,.,.;SpliceAI_pred_DP_AL=.,.,.;SpliceAI_pred_DP_DG=.,.,.;SpliceAI_pred_DP_DL=.,.,.;SpliceAI_pred_DS_AG=.,.,.;SpliceAI_pred_DS_AL=.,.,.;SpliceAI_pred_DS_DG=.,.,.;SpliceAI_pred_DS_DL=.,.,.;SpliceAI_pred_SYMBOL=.,.,. bcftools-1.21/test/split-vep.19.out000066400000000000000000000404261467060157400171530ustar00rootroot000000000000001 979496 . T C . . CSQ=C|missense_variant|MODERATE|PERM1|ENSG00000187642|Transcript|ENST00000341290|protein_coding|3/5||ENST00000341290.6:c.1192A>G|ENSP00000343864.2:p.Ser398Gly|1228|1192|398|S/G|Agc/Ggc|rs13302983||-1||SNV|HGNC|HGNC:28208|||2|A2||ENSP00000343864|Q5SV97||||tolerated(0.2)|benign(0.003)|PANTHER:PTHR47282&MobiDB_lite:mobidb-lite||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379407|protein_coding||||||||||rs13302983|4488|1||SNV|HGNC|HGNC:25284|||1|A2|CCDS53256.1|ENSP00000368717|Q494U1||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379409|protein_coding||||||||||rs13302983|4488|1||SNV|HGNC|HGNC:25284|||2|A2||ENSP00000368719|Q494U1||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379410|protein_coding||||||||||rs13302983|3631|1||SNV|HGNC|HGNC:25284|YES|NM_032129.3|1|P3|CCDS4.1|ENSP00000368720|Q494U1||UPI00001416D8||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|missense_variant|MODERATE|PERM1|ENSG00000187642|Transcript|ENST00000433179|protein_coding|1/3||ENST00000433179.3:c.1534A>G|ENSP00000414022.3:p.Ser512Gly|1534|1534|512|S/G|Agc/Ggc|rs13302983||-1||SNV|HGNC|HGNC:28208|YES||5|P2|CCDS76083.1|ENSP00000414022|Q5SV97||||tolerated(0.18)|benign(0.011)|PANTHER:PTHR47282&MobiDB_lite:mobidb-lite||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|upstream_gene_variant|MODIFIER|PERM1|ENSG00000187642|Transcript|ENST00000479361|retained_intron||||||||||rs13302983|2855|-1||SNV|HGNC|HGNC:28208|||1||||||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000491024|protein_coding||||||||||rs13302983|3631|1|cds_start_NF|SNV|HGNC|HGNC:25284|||3|||ENSP00000462558||J3KSM5|UPI000268AE1F||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1;Allele=C;Consequence=missense_variant;IMPACT=MODERATE;SYMBOL=PERM1;Gene=ENSG00000187642;Feature_type=Transcript;Feature=ENST00000341290;BIOTYPE=protein_coding;EXON=3/5;INTRON=.;HGVSc=ENST00000341290.6:c.1192A>G;HGVSp=ENSP00000343864.2:p.Ser398Gly;cDNA_position=1228;CDS_position=1192;Protein_position=398;Amino_acids=S/G;Codons=Agc/Ggc;Existing_variation=rs13302983;DISTANCE=.;STRAND=-1;FLAGS=.;VARIANT_CLASS=SNV;SYMBOL_SOURCE=HGNC;HGNC_ID=HGNC:28208;CANONICAL=.;MANE=.;TSL=2;APPRIS=A2;CCDS=.;ENSP=ENSP00000343864;SWISSPROT=Q5SV97;TREMBL=.;UNIPARC=.;GENE_PHENO=.;SIFT=tolerated(0.2);PolyPhen=benign(0.003);DOMAINS=PANTHER:PTHR47282&MobiDB_lite:mobidb-lite;miRNA=.;HGVS_OFFSET=.;AF=.;AFR_AF=0.9418;AMR_AF=0.9539;EAS_AF=0.999;EUR_AF=0.9592;SAS_AF=0.9847;AA_AF=.;EA_AF=.;gnomAD_AF=0.9721;gnomAD_AFR_AF=0.9533;gnomAD_AMR_AF=0.9754;gnomAD_ASJ_AF=0.9166;gnomAD_EAS_AF=0.9999;gnomAD_FIN_AF=0.9923;gnomAD_NFE_AF=0.9677;gnomAD_OTH_AF=0.9536;gnomAD_SAS_AF=0.9811;MAX_AF=0.9999;MAX_AF_POPS=gnomAD_EAS;CLIN_SIG=.;SOMATIC=.;PHENO=.;PUBMED=.;MOTIF_NAME=.;MOTIF_POS=.;HIGH_INF_POS=.;MOTIF_SCORE_CHANGE=.;existing_InFrame_oORFs=.;existing_OutOfFrame_oORFs=.;existing_uORFs=.;five_prime_UTR_variant_annotation=.;five_prime_UTR_variant_consequence=.;SpliceRegion=.;LoF=.;LoF_filter=.;LoF_flags=.;LoF_info=.;SpliceAI_pred_DP_AG=-27;SpliceAI_pred_DP_AL=-2;SpliceAI_pred_DP_DG=23;SpliceAI_pred_DP_DL=25;SpliceAI_pred_DS_AG=0;SpliceAI_pred_DS_AL=0;SpliceAI_pred_DS_DG=0;SpliceAI_pred_DS_DL=0;SpliceAI_pred_SYMBOL=PERM1 1 979560 . T C . . CSQ=C|synonymous_variant|LOW|PERM1|ENSG00000187642|Transcript|ENST00000341290|protein_coding|3/5||ENST00000341290.6:c.1128A>G|ENSP00000343864.2:p.Ala376%3D|1164|1128|376|A|gcA/gcG|rs13303033||-1||SNV|HGNC|HGNC:28208|||2|A2||ENSP00000343864|Q5SV97||||||PANTHER:PTHR47282&Low_complexity_(Seg):seg|||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379407|protein_coding||||||||||rs13303033|4552|1||SNV|HGNC|HGNC:25284|||1|A2|CCDS53256.1|ENSP00000368717|Q494U1|||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379409|protein_coding||||||||||rs13303033|4552|1||SNV|HGNC|HGNC:25284|||2|A2||ENSP00000368719|Q494U1|||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379410|protein_coding||||||||||rs13303033|3695|1||SNV|HGNC|HGNC:25284|YES|NM_032129.3|1|P3|CCDS4.1|ENSP00000368720|Q494U1||UPI00001416D8|||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|synonymous_variant|LOW|PERM1|ENSG00000187642|Transcript|ENST00000433179|protein_coding|1/3||ENST00000433179.3:c.1470A>G|ENSP00000414022.3:p.Ala490%3D|1470|1470|490|A|gcA/gcG|rs13303033||-1||SNV|HGNC|HGNC:28208|YES||5|P2|CCDS76083.1|ENSP00000414022|Q5SV97||||||PANTHER:PTHR47282&Low_complexity_(Seg):seg|||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|upstream_gene_variant|MODIFIER|PERM1|ENSG00000187642|Transcript|ENST00000479361|retained_intron||||||||||rs13303033|2919|-1||SNV|HGNC|HGNC:28208|||1|||||||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000491024|protein_coding||||||||||rs13303033|3695|1|cds_start_NF|SNV|HGNC|HGNC:25284|||3|||ENSP00000462558||J3KSM5|UPI000268AE1F|||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1;Allele=C;Consequence=synonymous_variant;IMPACT=LOW;SYMBOL=PERM1;Gene=ENSG00000187642;Feature_type=Transcript;Feature=ENST00000341290;BIOTYPE=protein_coding;EXON=3/5;INTRON=.;HGVSc=ENST00000341290.6:c.1128A>G;HGVSp=ENSP00000343864.2:p.Ala376%3D;cDNA_position=1164;CDS_position=1128;Protein_position=376;Amino_acids=A;Codons=gcA/gcG;Existing_variation=rs13303033;DISTANCE=.;STRAND=-1;FLAGS=.;VARIANT_CLASS=SNV;SYMBOL_SOURCE=HGNC;HGNC_ID=HGNC:28208;CANONICAL=.;MANE=.;TSL=2;APPRIS=A2;CCDS=.;ENSP=ENSP00000343864;SWISSPROT=Q5SV97;TREMBL=.;UNIPARC=.;GENE_PHENO=.;SIFT=.;PolyPhen=.;DOMAINS=PANTHER:PTHR47282&Low_complexity_(Seg):seg;miRNA=.;HGVS_OFFSET=.;AF=0.5096;AFR_AF=0.177;AMR_AF=0.6095;EAS_AF=0.7123;EUR_AF=0.5895;SAS_AF=0.5971;AA_AF=.;EA_AF=.;gnomAD_AF=0.5887;gnomAD_AFR_AF=0.2428;gnomAD_AMR_AF=0.6604;gnomAD_ASJ_AF=0.5617;gnomAD_EAS_AF=0.7237;gnomAD_FIN_AF=0.5334;gnomAD_NFE_AF=0.5801;gnomAD_OTH_AF=0.5647;gnomAD_SAS_AF=0.6213;MAX_AF=0.7237;MAX_AF_POPS=gnomAD_EAS;CLIN_SIG=.;SOMATIC=.;PHENO=.;PUBMED=.;MOTIF_NAME=.;MOTIF_POS=.;HIGH_INF_POS=.;MOTIF_SCORE_CHANGE=.;existing_InFrame_oORFs=.;existing_OutOfFrame_oORFs=.;existing_uORFs=.;five_prime_UTR_variant_annotation=.;five_prime_UTR_variant_consequence=.;SpliceRegion=.;LoF=.;LoF_filter=.;LoF_flags=.;LoF_info=.;SpliceAI_pred_DP_AG=28;SpliceAI_pred_DP_AL=-30;SpliceAI_pred_DP_DG=-39;SpliceAI_pred_DP_DL=3;SpliceAI_pred_DS_AG=0;SpliceAI_pred_DS_AL=0;SpliceAI_pred_DS_DG=0;SpliceAI_pred_DS_DL=0;SpliceAI_pred_SYMBOL=PERM1 1 999842 . C A . . CSQ=A|intron_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000304952|protein_coding||1/3|ENST00000304952.11:c.108+24G>T|||||||rs2298214||-1||SNV|HGNC|HGNC:24149||NM_021170.4|1|P1|CCDS5.1|ENSP00000304595|Q9HCC6|||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|missense_variant|MODERATE|HES4|ENSG00000188290|Transcript|ENST00000428771|protein_coding|1/3||ENST00000428771.6:c.132G>T|ENSP00000393198.2:p.Arg44Ser|331|132|44|R/S|agG/agT|rs2298214||-1||SNV|HGNC|HGNC:24149|YES||2||CCDS44034.1|ENSP00000393198||E9PB28|UPI0001881B51||tolerated_low_confidence(0.72)|benign(0)|MobiDB_lite:mobidb-lite&Low_complexity_(Seg):seg|||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS||||||||||||||||||MUTANT_DONOR_MES:11.0784944978449&EXON_END:1000172&INTRON_END:999691&DE_NOVO_DONOR_MES_POS:-156&DE_NOVO_DONOR_POS:-156&EXON_START:999692&DE_NOVO_DONOR_MES:7.0006176073036&DE_NOVO_DONOR_PROB:0.167156964545091&INTRON_START:999614|6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|non_coding_transcript_exon_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000481869|retained_intron|1/2||ENST00000481869.1:n.255G>T||255|||||rs2298214||-1||SNV|HGNC|HGNC:24149|||2|||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|intron_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000484667|protein_coding||1/2|ENST00000484667.2:c.108+24G>T|||||||rs2298214||-1||SNV|HGNC|HGNC:24149|||3|||ENSP00000425085||D6REB3|UPI0001D3BBEE|||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|AL645608.7|ENSG00000272512|Transcript|ENST00000606034|lncRNA||||||||||rs2298214|1791|-1||SNV|Clone_based_ensembl_gene||YES|||||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|ISG15|ENSG00000187608|Transcript|ENST00000624652|protein_coding||||||||||rs2298214|1303|1|cds_end_NF|SNV|HGNC|HGNC:4053|||3|||ENSP00000485313||A0A096LNZ9||1||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|ISG15|ENSG00000187608|Transcript|ENST00000624697|protein_coding||||||||||rs2298214|1296|1||SNV|HGNC|HGNC:4053|||3|A2||ENSP00000485643||A0A096LPJ4||1||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000118|promoter||||||||||rs2298214||||SNV||||||||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||||||||||;Allele=A;Consequence=missense_variant;IMPACT=MODERATE;SYMBOL=HES4;Gene=ENSG00000188290;Feature_type=Transcript;Feature=ENST00000428771;BIOTYPE=protein_coding;EXON=1/3;INTRON=.;HGVSc=ENST00000428771.6:c.132G>T;HGVSp=ENSP00000393198.2:p.Arg44Ser;cDNA_position=331;CDS_position=132;Protein_position=44;Amino_acids=R/S;Codons=agG/agT;Existing_variation=rs2298214;DISTANCE=.;STRAND=-1;FLAGS=.;VARIANT_CLASS=SNV;SYMBOL_SOURCE=HGNC;HGNC_ID=HGNC:24149;CANONICAL=YES;MANE=.;TSL=2;APPRIS=.;CCDS=CCDS44034.1;ENSP=ENSP00000393198;SWISSPROT=.;TREMBL=E9PB28;UNIPARC=UPI0001881B51;GENE_PHENO=.;SIFT=tolerated_low_confidence(0.72);PolyPhen=benign(0);DOMAINS=MobiDB_lite:mobidb-lite&Low_complexity_(Seg):seg;miRNA=.;HGVS_OFFSET=.;AF=0.4938;AFR_AF=0.0356;AMR_AF=0.6268;EAS_AF=0.7718;EUR_AF=0.5895;SAS_AF=0.6339;AA_AF=0.1386;EA_AF=0.5695;gnomAD_AF=0.6136;gnomAD_AFR_AF=0.1208;gnomAD_AMR_AF=0.7139;gnomAD_ASJ_AF=0.6344;gnomAD_EAS_AF=0.786;gnomAD_FIN_AF=0.5555;gnomAD_NFE_AF=0.595;gnomAD_OTH_AF=0.5882;gnomAD_SAS_AF=0.6625;MAX_AF=0.786;MAX_AF_POPS=gnomAD_EAS;CLIN_SIG=.;SOMATIC=.;PHENO=.;PUBMED=.;MOTIF_NAME=.;MOTIF_POS=.;HIGH_INF_POS=.;MOTIF_SCORE_CHANGE=.;existing_InFrame_oORFs=.;existing_OutOfFrame_oORFs=.;existing_uORFs=.;five_prime_UTR_variant_annotation=.;five_prime_UTR_variant_consequence=.;SpliceRegion=.;LoF=.;LoF_filter=.;LoF_flags=.;LoF_info=MUTANT_DONOR_MES:11.0784944978449&EXON_END:1000172&INTRON_END:999691&DE_NOVO_DONOR_MES_POS:-156&DE_NOVO_DONOR_POS:-156&EXON_START:999692&DE_NOVO_DONOR_MES:7.0006176073036&DE_NOVO_DONOR_PROB:0.167156964545091&INTRON_START:999614;SpliceAI_pred_DP_AG=6;SpliceAI_pred_DP_AL=-37;SpliceAI_pred_DP_DG=6;SpliceAI_pred_DP_DL=24;SpliceAI_pred_DS_AG=0;SpliceAI_pred_DS_AL=0;SpliceAI_pred_DS_DG=0.01;SpliceAI_pred_DS_DL=0.02;SpliceAI_pred_SYMBOL=HES4 1 12716215 . C A . . CSQ=A|stop_gained|HIGH|AADACL3|ENSG00000188984|Transcript|ENST00000359318|protein_coding|1/4||ENST00000359318.8:c.39C>A|ENSP00000352268.6:p.Cys13Ter|106|39|13|C/*|tgC/tgA|rs3000860||1||SNV|HGNC|HGNC:32037|YES|NM_001103170.3|3|P1|CCDS41253.2|ENSP00000352268|Q5VUY0||UPI0003EAEC70||||PIRSF:PIRSF037251&PANTHER:PTHR23024&PANTHER:PTHR23024:SF115&Transmembrane_helices:TMhelix|||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||HC|||GERP_DIST:92.57575&BP_DIST:1182&PERCENTILE:0.0318627450980392&DIST_FROM_LAST_EXON:408&50_BP_RULE:PASS&PHYLOCSF_TOO_SHORT|||||||||,A|non_coding_transcript_exon_variant|MODIFIER|AADACL3|ENSG00000188984|Transcript|ENST00000620146|processed_transcript|1/3||ENST00000620146.2:n.101C>A||101|||||rs3000860||1||SNV|HGNC|HGNC:32037|||2|||||||||||||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000347677|promoter_flanking_region||||||||||rs3000860||||SNV||||||||||||||||||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||||||||||||||;Allele=A;Consequence=stop_gained;IMPACT=HIGH;SYMBOL=AADACL3;Gene=ENSG00000188984;Feature_type=Transcript;Feature=ENST00000359318;BIOTYPE=protein_coding;EXON=1/4;INTRON=.;HGVSc=ENST00000359318.8:c.39C>A;HGVSp=ENSP00000352268.6:p.Cys13Ter;cDNA_position=106;CDS_position=39;Protein_position=13;Amino_acids=C/*;Codons=tgC/tgA;Existing_variation=rs3000860;DISTANCE=.;STRAND=1;FLAGS=.;VARIANT_CLASS=SNV;SYMBOL_SOURCE=HGNC;HGNC_ID=HGNC:32037;CANONICAL=YES;MANE=NM_001103170.3;TSL=3;APPRIS=P1;CCDS=CCDS41253.2;ENSP=ENSP00000352268;SWISSPROT=Q5VUY0;TREMBL=.;UNIPARC=UPI0003EAEC70;GENE_PHENO=.;SIFT=.;PolyPhen=.;DOMAINS=PIRSF:PIRSF037251&PANTHER:PTHR23024&PANTHER:PTHR23024:SF115&Transmembrane_helices:TMhelix;miRNA=.;HGVS_OFFSET=.;AF=0.1436;AFR_AF=0.1188;AMR_AF=0.1052;EAS_AF=0.2679;EUR_AF=0.1362;SAS_AF=0.0838;AA_AF=.;EA_AF=.;gnomAD_AF=.;gnomAD_AFR_AF=.;gnomAD_AMR_AF=.;gnomAD_ASJ_AF=.;gnomAD_EAS_AF=.;gnomAD_FIN_AF=.;gnomAD_NFE_AF=.;gnomAD_OTH_AF=.;gnomAD_SAS_AF=.;MAX_AF=0.2679;MAX_AF_POPS=EAS;CLIN_SIG=.;SOMATIC=.;PHENO=.;PUBMED=.;MOTIF_NAME=.;MOTIF_POS=.;HIGH_INF_POS=.;MOTIF_SCORE_CHANGE=.;existing_InFrame_oORFs=.;existing_OutOfFrame_oORFs=.;existing_uORFs=.;five_prime_UTR_variant_annotation=.;five_prime_UTR_variant_consequence=.;SpliceRegion=.;LoF=HC;LoF_filter=.;LoF_flags=.;LoF_info=GERP_DIST:92.57575&BP_DIST:1182&PERCENTILE:0.0318627450980392&DIST_FROM_LAST_EXON:408&50_BP_RULE:PASS&PHYLOCSF_TOO_SHORT;SpliceAI_pred_DP_AG=.;SpliceAI_pred_DP_AL=.;SpliceAI_pred_DP_DG=.;SpliceAI_pred_DP_DL=.;SpliceAI_pred_DS_AG=.;SpliceAI_pred_DS_AL=.;SpliceAI_pred_DS_DG=.;SpliceAI_pred_DS_DL=.;SpliceAI_pred_SYMBOL=. bcftools-1.21/test/split-vep.2.out000066400000000000000000000011541467060157400170560ustar00rootroot0000000000000015004 splice_donor_variant&non_coding_transcript_variant 16856 splice_donor_variant&non_coding_transcript_variant 17365 splice_acceptor_variant&non_coding_transcript_variant 69428 missense_variant 69469 frameshift_variant 69496 missense_variant 69511 missense_variant 69559 missense_variant 69569 missense_variant 69590 missense_variant 69604 missense_variant 69610 missense_variant 69634 missense_variant 69640 missense_variant 69678 missense_variant 69713 missense_variant 69719 stop_gained 69761 missense_variant 69808 missense_variant 69816 missense_variant 752752 splice_donor_variant&non_coding_transcript_variant bcftools-1.21/test/split-vep.2.vcf000066400000000000000000000151341467060157400170300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 14464 . A T 2235.88 PASS AF=1;CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1568T>A||1568|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1682T>A||1682|||||rs546169444|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs546169444|1|55|1||SNV|HGNC|37102|YES|||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|11/11||ENST00000488147.1:n.1291T>A||1291|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|13/13||ENST00000538476.1:n.1530T>A||1530|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1315T>A||1315|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000002|open_chromatin_region||||||||||rs546169444|1||||SNV||||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||;BCSQ=non_coding|WASH7P||unprocessed_pseudogene 1 14469 . C T 37.38 PASS AF=0.5;CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1563G>A||1563||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1677G>A||1677||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|60|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|11/11||ENST00000488147.1:n.1286G>A||1286||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|13/13||ENST00000538476.1:n.1525G>A||1525||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1310G>A||1310||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000002|open_chromatin_region|||||||||||1||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||;BCSQ=non_coding|WASH7P||unprocessed_pseudogene 1 14522 . G A 627.64 PASS AF=0.2;CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1510C>T||1510||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1624C>T||1624||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|113|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-21C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-20C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1257C>T||1257||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||;BCSQ=non_coding|WASH7P||unprocessed_pseudogene bcftools-1.21/test/split-vep.20.out000066400000000000000000000030451467060157400171370ustar00rootroot00000000000000chr1 817186 . G A 50 PASS ANN=A|upstream_gene_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lncRNA||||||||||rs3094315|185|1||SNV|HGNC|HGNC:32236|YES||2||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|AL669831.4|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||1/4|ENST00000447500.4:n.340+187C>T|||||||rs3094315||-1||SNV|Clone_based_ensembl_gene||YES||5||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|AL669831.3|ENSG00000230021|Transcript|ENST00000634337|processed_transcript||1/4|ENST00000634337.2:n.127+10484C>T|||||||rs3094315||-1||SNV|Clone_based_ensembl_gene||||5||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|AL669831.3|ENSG00000230021|Transcript|ENST00000635509|processed_transcript||1/3|ENST00000635509.2:n.100+10484C>T|||||||rs3094315||-1||SNV|Clone_based_ensembl_gene||||5||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000085|promoter||||||||||rs3094315||||SNV|||||||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||;IMPACT=MODIFIER,MODIFIER,MODIFIER,MODIFIER,MODIFIER GT 1|1 bcftools-1.21/test/split-vep.21.out000066400000000000000000000007341467060157400171420ustar00rootroot000000000000001 145075172 . G A . . BCSQ=intron|PDE4DIP||protein_coding;Consequence=intron;amino_acid_change=. 2 175216515 . A G . . BCSQ=intron|CIR1||protein_coding;Consequence=intron;amino_acid_change=. 20 37400393 . C T . . BCSQ=synonymous|ACTR5|ENST00000243903|protein_coding|+|586S|37400393C>T;Consequence=synonymous;amino_acid_change=586S X 48822646 . T G . . BCSQ=missense|KCND1|ENST00000376477|protein_coding|-|135T>135P|48822646T>G;Consequence=missense;amino_acid_change=135T>135P bcftools-1.21/test/split-vep.22.out000066400000000000000000000004371467060157400171430ustar00rootroot00000000000000145075172 intron . intron|PDE4DIP||protein_coding 175216515 intron . intron|CIR1||protein_coding 37400393 synonymous 586S synonymous|ACTR5|ENST00000243903|protein_coding|+|586S|37400393C>T 48822646 missense 135T>135P missense|KCND1|ENST00000376477|protein_coding|-|135T>135P|48822646T>G bcftools-1.21/test/split-vep.23.out000066400000000000000000000001021467060157400171310ustar00rootroot000000000000001 145075172 G A intron PDE4DIP . protein_coding . . . 145075172 2 bcftools-1.21/test/split-vep.24.out000066400000000000000000000000131467060157400171330ustar00rootroot00000000000000111 intron bcftools-1.21/test/split-vep.25.out000066400000000000000000000000131467060157400171340ustar00rootroot00000000000000D 0.293271 bcftools-1.21/test/split-vep.26.out000066400000000000000000000002231467060157400171400ustar00rootroot00000000000000860416 860417 860431 860461 860498 860504 860511 860521 860564 860604 860607 860637 860684 860688 861172 861177 861178 861196 861209 861211 861213 bcftools-1.21/test/split-vep.27.out000066400000000000000000000000261467060157400171420ustar00rootroot0000000000000069511 0.9995 792480 1 bcftools-1.21/test/split-vep.3.out000066400000000000000000000007721467060157400170640ustar00rootroot0000000000000017365 splice_acceptor_variant&non_coding_transcript_variant 69428 missense_variant 69469 frameshift_variant 69496 missense_variant 69511 missense_variant 69559 missense_variant 69569 missense_variant 69590 missense_variant 69604 missense_variant 69610 missense_variant 69634 missense_variant 69640 missense_variant 69678 missense_variant 69713 missense_variant 69719 stop_gained 69761 missense_variant 69808 missense_variant 69816 missense_variant 752752 splice_donor_variant&non_coding_transcript_variant bcftools-1.21/test/split-vep.3.vcf000066400000000000000000000144021467060157400170260ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SMPLA SMPLB 1 14464 . A T 2235.88 PASS AF=1;CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1568T>A||1568|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1682T>A||1682|||||rs546169444|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs546169444|1|55|1||SNV|HGNC|37102|YES|||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|11/11||ENST00000488147.1:n.1291T>A||1291|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|13/13||ENST00000538476.1:n.1530T>A||1530|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1315T>A||1315|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000002|open_chromatin_region||||||||||rs546169444|1||||SNV||||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS||||||||||||||||||||||||| GT 0/0 0/1 1 14469 . C T 37.38 PASS AF=0.5;CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1563G>A||1563||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1677G>A||1677||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|60|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|11/11||ENST00000488147.1:n.1286G>A||1286||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|13/13||ENST00000538476.1:n.1525G>A||1525||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1310G>A||1310||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000002|open_chromatin_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| GT 0/0 0/1 1 14522 . G A 627.64 PASS AF=0.2;CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1510C>T||1510||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1624C>T||1624||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|113|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-21C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-20C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1257C>T||1257||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| GT 0/0 0/1 bcftools-1.21/test/split-vep.4.out000066400000000000000000000001631467060157400170570ustar00rootroot0000000000000017365 69428 69469 69496 69511 69559 69569 69590 69604 69610 69634 69640 69678 69713 69719 69761 69808 69816 752752 bcftools-1.21/test/split-vep.4.vcf000066400000000000000000000233761467060157400170410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 14464 . A T 2235.88 PASS AF=1;BCSQ=non_coding|WASH7P||unprocessed_pseudogene 1 66053 . G A 65.5 PASS . 1 66055 . C G 576.85 PASS . 1 69270 . A G 64453.2 PASS BCSQ=synonymous|OR4F5|ENST00000335137|protein_coding|+|60S|69270A>G 1 69428 . T G 455238 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|113F>113C|69428T>G 1 69438 . T C 28054.4 PASS BCSQ=synonymous|OR4F5|ENST00000335137|protein_coding|+|116Y|69438T>C 1 69453 . G A 49.81 PASS BCSQ=synonymous|OR4F5|ENST00000335137|protein_coding|+|121K|69453G>A 1 69640 . G C 360.75 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|184D>184H|69640G>C 1 69678 . T A 231.22 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|196S>196R|69678T>A 1 69690 . T A 289.94 PASS BCSQ=synonymous|OR4F5|ENST00000335137|protein_coding|+|200T|69690T>A 1 69696 . T C 37.01 PASS BCSQ=synonymous|OR4F5|ENST00000335137|protein_coding|+|202C|69696T>C 1 69713 . T C 498.13 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|208I>208T|69713T>C 1 69719 . C G 7943.31 PASS BCSQ=stop_gained|OR4F5|ENST00000335137|protein_coding|+|210S>210*|69719C>G 1 69761 . A T 180095 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|224D>224V|69761A>T 1 69808 . G C 52.73 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|240V>240L|69808G>C 1 69816 . G C 158.87 PASS BCSQ=missense|OR4F5|ENST00000335137|protein_coding|+|242L>242F|69816G>C 1 69897 . T C 21493.6 PASS BCSQ=synonymous|OR4F5|ENST00000335137|protein_coding|+|269S|69897T>C 1 120705 . T C 4309.8 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 120745 . C T 2554.27 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 121028 . CTA C 81.23 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 129077 . G A 84.32 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 129122 . A G 121.6 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 129148 . GT GTT,G 343484 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 129285 . G A 6740.47 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 129301 . T C 36.87 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 129315 . A G 1616.86 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA 1 133355 . G T 107.63 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA,non_coding|CICP27||processed_pseudogene 1 133392 . G A 31.55 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA,non_coding|CICP27||processed_pseudogene 1 133477 . G T 40.05 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA,non_coding|CICP27||processed_pseudogene 1 133483 . G T 143466 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA,non_coding|CICP27||processed_pseudogene 1 133558 . C T 1041.19 PASS BCSQ=non_coding|RP11-34P13.7||lincRNA,non_coding|CICP27||processed_pseudogene 1 135147 . G A 1291.73 PASS BCSQ=3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 135151 . G A 2099.5 PASS BCSQ=3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 135232 . C T 6306.06 PASS BCSQ=3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 135265 . T C 98.15 PASS BCSQ=3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 135297 . C T 292.28 PASS BCSQ=3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 135982 . A G 3509.37 PASS BCSQ=intron|AL627309.1||protein_coding 1 136041 . C A 72.79 PASS BCSQ=intron|AL627309.1||protein_coding 1 136124 . G A 99.63 PASS BCSQ=intron|AL627309.1||protein_coding 1 136210 . G A 129.71 PASS BCSQ=intron|AL627309.1||protein_coding 1 137622 . G A 240.87 PASS BCSQ=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 137825 . G A 119793 PASS BCSQ=3_prime_utr|AL627309.1|ENST00000423372|protein_coding 1 267099 . C G 192.81 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267132 . T C 3289.74 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267147 . G A 142.23 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267154 . C T 19978.8 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267216 . C T 187.14 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267220 . A C 213.29 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267226 . C A 66.52 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267227 . TTAA T 101119 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267229 . A *,C 156630 PASS BCSQ=non_coding|AP006222.2||lincRNA 1 267268 . A C 1112.11 PASS . 1 267276 . A G 1380.44 PASS . 1 267282 . T C 690.8 PASS . 1 267289 . T TTA 2809.66 PASS . 1 267295 . A C,* 64218.9 PASS . 1 267300 . T *,TTA 53059.2 PASS . 1 267303 . T *,C 62423.3 PASS . 1 267305 . TATA *,T,CATA 144971 PASS . 1 267309 . ATAT *,TTAT 145363 PASS . 1 267310 . T *,A 63099.9 PASS . 1 267316 . ATATC *,A 77789.8 PASS . 1 267319 . T *,C 77970.5 PASS . 1 267324 . T *,G,C 185470 PASS . 1 267331 . T *,A 98694.5 PASS . 1 267355 . TATA T,* 182207 PASS . 1 267359 . ATAT *,A 146369 PASS . 1 647265 . C T 391.71 PASS BCSQ=non_coding|RP5-857K21.4||lincRNA 1 647380 . T C 1741.48 PASS BCSQ=non_coding|RP5-857K21.4||lincRNA 1 647398 . T C 680.51 PASS BCSQ=non_coding|RP5-857K21.4||lincRNA 1 662029 . G A 14832.6 PASS BCSQ=non_coding|RP11-206L10.1||unprocessed_pseudogene 1 662414 . C T 796.79 PASS BCSQ=non_coding|RP11-206L10.1||unprocessed_pseudogene 1 662531 . G A 382.5 PASS BCSQ=non_coding|RP11-206L10.1||unprocessed_pseudogene 1 722032 . C T 40.43 PASS BCSQ=non_coding|RP11-206L10.9||lincRNA 1 741163 . G A 67.26 PASS BCSQ=non_coding|RP11-206L10.9||lincRNA,non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript 1 741181 . T C 158.83 PASS BCSQ=non_coding|RP11-206L10.9||lincRNA,non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript 1 741235 . G A 13511.6 PASS BCSQ=non_coding|RP11-206L10.9||lincRNA,non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript 1 741260 . A G 191.75 PASS BCSQ=non_coding|RP11-206L10.9||lincRNA,non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript 1 741286 . CAG C 4534.64 PASS BCSQ=non_coding|RP11-206L10.9||lincRNA,non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript 1 745347 . T C 56.66 PASS BCSQ=non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript,non_coding|RP11-206L10.9||lincRNA 1 745370 . TA T 8641.83 PASS BCSQ=non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript,non_coding|RP11-206L10.9||lincRNA 1 745425 . AAATT A 251.88 PASS BCSQ=non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript,non_coding|RP11-206L10.9||lincRNA 1 745439 . G A 34303.8 PASS BCSQ=non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript,non_coding|RP11-206L10.9||lincRNA 1 745477 . C T 17109.4 PASS BCSQ=non_coding|RP11-206L10.8||transcribed_unprocessed_pseudogene,non_coding|RP11-206L10.8||processed_transcript 1 745573 . T G 276.91 PASS BCSQ=non_coding|RP11-206L10.10||processed_transcript 1 745620 . A G 166.67 PASS BCSQ=non_coding|RP11-206L10.10||processed_transcript 1 745642 . AC A 35881.9 PASS BCSQ=non_coding|RP11-206L10.10||processed_transcript 1 753001 . GT G 43.25 PASS BCSQ=non_coding|RP11-206L10.10||processed_transcript,non_coding|FAM87B||lincRNA 1 753016 . T C 40.09 PASS BCSQ=non_coding|RP11-206L10.10||processed_transcript,non_coding|FAM87B||lincRNA 1 753110 . G A 55.21 PASS BCSQ=non_coding|FAM87B||lincRNA 1 808662 . T C 285.9 PASS BCSQ=non_coding|FAM41C||lincRNA 1 808665 . C G 194.95 PASS BCSQ=non_coding|FAM41C||lincRNA 1 808672 . G T 174.78 PASS BCSQ=non_coding|FAM41C||lincRNA,non_coding|TUBB8P11||unprocessed_pseudogene 1 808695 . T C 140.85 PASS BCSQ=non_coding|FAM41C||lincRNA,non_coding|TUBB8P11||unprocessed_pseudogene 1 808708 . A G 182.54 PASS BCSQ=non_coding|FAM41C||lincRNA,non_coding|TUBB8P11||unprocessed_pseudogene 1 808710 . T A 2168.76 PASS BCSQ=non_coding|FAM41C||lincRNA,non_coding|TUBB8P11||unprocessed_pseudogene 1 808714 . C T 184.47 PASS BCSQ=non_coding|FAM41C||lincRNA,non_coding|TUBB8P11||unprocessed_pseudogene 1 808723 . C G 289.66 PASS BCSQ=non_coding|FAM41C||lincRNA,non_coding|TUBB8P11||unprocessed_pseudogene 1 809768 . A C 2167.1 PASS BCSQ=non_coding|FAM41C||lincRNA 1 860416 . G A 616869 PASS BCSQ=intron|SAMD11||protein_coding 1 860417 . G T 38.51 PASS BCSQ=intron|SAMD11||protein_coding 1 860431 . G T 12736.1 PASS BCSQ=intron|SAMD11||protein_coding 1 860461 . G A 822612 PASS BCSQ=intron|SAMD11||protein_coding 1 860498 . C G 61631.5 PASS BCSQ=intron|SAMD11||protein_coding 1 860504 . G A 2021.16 PASS BCSQ=intron|SAMD11||protein_coding 1 860511 . C T 66.9 PASS BCSQ=intron|SAMD11||protein_coding 1 860521 . C A 1.14406e+06 PASS BCSQ=intron|SAMD11||protein_coding 1 860564 . C T 149.61 PASS BCSQ=5_prime_utr|SAMD11|ENST00000437963|protein_coding 1 860604 . G A 37.35 PASS BCSQ=intron|SAMD11||protein_coding 1 860607 . A G 302.91 PASS BCSQ=intron|SAMD11||protein_coding 1 860637 . AG A 176.75 PASS BCSQ=intron|SAMD11||protein_coding 1 860684 . G A 77.88 PASS BCSQ=intron|SAMD11||protein_coding 1 860688 . G A 1.42925e+06 PASS BCSQ=intron|SAMD11||protein_coding 1 861172 . C T 44.68 PASS BCSQ=5_prime_utr|SAMD11|ENST00000342066|protein_coding 1 861177 . C A 271.27 PASS BCSQ=5_prime_utr|SAMD11|ENST00000342066|protein_coding 1 861178 . G A 253.29 PASS BCSQ=splice_region&5_prime_utr|SAMD11|ENST00000342066|protein_coding 1 861196 . G C 167.05 PASS BCSQ=intron|SAMD11||protein_coding 1 861209 . T A 120.43 PASS BCSQ=intron|SAMD11||protein_coding 1 861211 . C T 537.5 PASS BCSQ=intron|SAMD11||protein_coding 1 861213 . C T 69.71 PASS BCSQ=intron|SAMD11||protein_coding bcftools-1.21/test/split-vep.5.out000066400000000000000000000000151467060157400170540ustar00rootroot0000000000000014464 0.0958 bcftools-1.21/test/split-vep.5.vcf000066400000000000000000000216421467060157400170340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 69270 . A G 64453.2 PASS CSQ=G|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.180A>G|ENSP00000334393.3:p.Ser60%3D|180|180|60|S|tcA/tcG|rs201219564|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Low_complexity_(Seg):seg&Transmembrane_helices:TMhelix&Prints_domain:PR00237&PROSITE_profiles:PS50262|||||||||||0.8327|0.3603|0.7916|0.8434|0.9983|0.877|0.9112|0.8481|0.9018|0.9983|gnomAD_EAS|||||||||||||||rs201219564|7.81540e-01|9.98354e-01|3.59079e-01|7.93243e-01|8.48238e-01|9.98354e-01|8.82051e-01|9.14571e-01|8.68043e-01|9.00541e-01,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs201219564|1||||SNV||||||||||||||||||||||||||0.8327|0.3603|0.7916|0.8434|0.9983|0.877|0.9112|0.8481|0.9018|0.9983|gnomAD_EAS|||||||||||||||rs201219564|7.81540e-01|9.98354e-01|3.59079e-01|7.93243e-01|8.48238e-01|9.98354e-01|8.82051e-01|9.14571e-01|8.68043e-01|9.00541e-01 1 69428 . T G 455238 PASS CSQ=G|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.338T>G|ENSP00000334393.3:p.Phe113Cys|338|338|113|F/C|tTt/tGt|rs140739101|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.01)|probably_damaging(0.984)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00237&PROSITE_patterns:PS00237&PROSITE_profiles:PS50262|||0.0190|0.0015|0.036|0.003|0.0497|0.0153|0.003663|0.04571|0.02436|0.003129|0.009178|0.01338|0|0.04895|0.04092|0.02573|0.004991|0.0497|EUR|||||||||||||||rs140739101|2.15376e-02|4.17497e-02|3.34821e-03|9.05886e-03|1.39643e-02|0.00000e+00|4.83761e-02|4.17497e-02|2.93512e-02|4.97165e-03,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs140739101|1||||SNV||||||||||||||||||0.0190|0.0015|0.036|0.003|0.0497|0.0153|0.003663|0.04571|0.02436|0.003129|0.009178|0.01338|0|0.04895|0.04092|0.02573|0.004991|0.0497|EUR|||||||||||||||rs140739101|2.15376e-02|4.17497e-02|3.34821e-03|9.05886e-03|1.39643e-02|0.00000e+00|4.83761e-02|4.17497e-02|2.93512e-02|4.97165e-03 1 69438 . T C 28054.4 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.348T>C|ENSP00000334393.3:p.Tyr116%3D|348|348|116|Y|taT/taC|rs758790416|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Prints_domain:PR00237&PROSITE_patterns:PS00237&PROSITE_profiles:PS50262|||||||||||0.0001165|0|0|0|0|0|0.0002685|0|0|0.0002685|gnomAD_NFE|||||||||||||||rs758790416|9.66548e-05|2.64028e-04|0.00000e+00|9.71062e-05|0.00000e+00|0.00000e+00|0.00000e+00|2.64028e-04|0.00000e+00|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs758790416|1||||SNV||||||||||||||||||||||||||0.0001165|0|0|0|0|0|0.0002685|0|0|0.0002685|gnomAD_NFE|||||||||||||||rs758790416|9.66548e-05|2.64028e-04|0.00000e+00|9.71062e-05|0.00000e+00|0.00000e+00|0.00000e+00|2.64028e-04|0.00000e+00|0.00000e+00 1 69453 . G A 49.81 PASS CSQ=A|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.363G>A|ENSP00000334393.3:p.Lys121%3D|363|363|121|K|aaG/aaA|rs2854682|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||||||||||7.371e-05|0.0002519|0.0001502|0|0|0|5.667e-05|0|8.675e-05|0.0002519|gnomAD_AFR|||||||||||||||rs2854682|4.73394e-04|3.95946e-04|3.95946e-04|1.45829e-04|0.00000e+00|0.00000e+00|0.00000e+00|6.96728e-05|0.00000e+00|8.71764e-05,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs2854682|1||||SNV||||||||||||||||||||||||||7.371e-05|0.0002519|0.0001502|0|0|0|5.667e-05|0|8.675e-05|0.0002519|gnomAD_AFR|||||||||||||||rs2854682|4.73394e-04|3.95946e-04|3.95946e-04|1.45829e-04|0.00000e+00|0.00000e+00|0.00000e+00|6.96728e-05|0.00000e+00|8.71764e-05 1 69469 . ACAATT A 305.81 PASS CSQ=-|frameshift_variant|HIGH|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.380_384del|ENSP00000334393.3:p.Thr127AsnfsTer38|380-384|380-384|127-128|TI/X|aCAATT/a||1||1||deletion|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00245&PROSITE_profiles:PS50262||||||||||||||||||||||||||||||HC||SINGLE_EXON|POSITION:0.418300653594771&PHYLOCSF_TOO_SHORT|||rs1350212330|9.20463e-06|8.71536e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|8.71536e-05 1 69486 . C T 3323 PASS CSQ=T|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.396C>T|ENSP00000334393.3:p.Asn132%3D|396|396|132|N|aaC/aaT|rs548369610|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00245&PROSITE_profiles:PS50262|||0.0002|0|0|0.001|0|0|||2.477e-05|0|0|0|0|0|5.737e-05|0|0|0.001|EAS|||||||||||||||rs548369610|1.90042e-05|5.64223e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.64223e-05|0.00000e+00|0.00000e+00 1 69489 . A C 1388.94 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.399A>C|ENSP00000334393.3:p.Ala133%3D|399|399|133|A|gcA/gcC|rs756368346|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00245&PROSITE_profiles:PS50262|||||||||||0.0001428|0|0|0|0|0|0|0|0.000999|0.000999|gnomAD_SAS|||||||||||||||rs756368346|1.15315e-04|1.00384e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.41475e-05|0.00000e+00|1.00384e-03 1 69496 . G A 2206.7 PASS CSQ=A|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.406G>A|ENSP00000334393.3:p.Gly136Ser|406|406|136|G/S|Ggc/Agc|rs150690004|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(0.4)|benign(0.061)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||0.0010|0.003|0.0014|0|0|0|0.00604|0.0002956|0.0006657|0.006109|0.00143|0|0|0|7.305e-05|0|8.709e-05|0.006109|gnomAD_AFR|||||||||||||||rs150690004|6.64393e-04|6.10650e-03|6.10650e-03|1.53709e-03|0.00000e+00|0.00000e+00|0.00000e+00|7.18061e-05|5.26316e-04|8.74967e-05 1 69511 . A G 2.06814e+07 PASS CSQ=G|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.421A>G|ENSP00000334393.3:p.Thr141Ala|421|421|141|T/A|Aca/Gca|rs2691305|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(0.82)|benign(0)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||0.5441|0.8874|0.9506|0.6074|0.9508|0.9779|0.9995|0.9915|0.9728|0.9499|0.9854|0.9995|gnomAD_EAS|||||||||||||||rs2691305|8.77680e-01|9.99439e-01|6.07496e-01|9.51366e-01|9.76661e-01|9.99439e-01|9.91577e-01|9.72624e-01|9.50621e-01|9.85395e-01 bcftools-1.21/test/split-vep.6.out000066400000000000000000000000341467060157400170560ustar00rootroot0000000000000014464 1 14469 0.5 14522 0.2 bcftools-1.21/test/split-vep.6.vcf000066400000000000000000000263541467060157400170420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 979496 . T C . . CSQ=C|missense_variant|MODERATE|PERM1|ENSG00000187642|Transcript|ENST00000341290|protein_coding|3/5||ENST00000341290.6:c.1192A>G|ENSP00000343864.2:p.Ser398Gly|1228|1192|398|S/G|Agc/Ggc|rs13302983||-1||SNV|HGNC|HGNC:28208|||2|A2||ENSP00000343864|Q5SV97||||tolerated(0.2)|benign(0.003)|PANTHER:PTHR47282&MobiDB_lite:mobidb-lite||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379407|protein_coding||||||||||rs13302983|4488|1||SNV|HGNC|HGNC:25284|||1|A2|CCDS53256.1|ENSP00000368717|Q494U1||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379409|protein_coding||||||||||rs13302983|4488|1||SNV|HGNC|HGNC:25284|||2|A2||ENSP00000368719|Q494U1||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379410|protein_coding||||||||||rs13302983|3631|1||SNV|HGNC|HGNC:25284|YES|NM_032129.3|1|P3|CCDS4.1|ENSP00000368720|Q494U1||UPI00001416D8||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|missense_variant|MODERATE|PERM1|ENSG00000187642|Transcript|ENST00000433179|protein_coding|1/3||ENST00000433179.3:c.1534A>G|ENSP00000414022.3:p.Ser512Gly|1534|1534|512|S/G|Agc/Ggc|rs13302983||-1||SNV|HGNC|HGNC:28208|YES||5|P2|CCDS76083.1|ENSP00000414022|Q5SV97||||tolerated(0.18)|benign(0.011)|PANTHER:PTHR47282&MobiDB_lite:mobidb-lite||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|upstream_gene_variant|MODIFIER|PERM1|ENSG00000187642|Transcript|ENST00000479361|retained_intron||||||||||rs13302983|2855|-1||SNV|HGNC|HGNC:28208|||1||||||||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000491024|protein_coding||||||||||rs13302983|3631|1|cds_start_NF|SNV|HGNC|HGNC:25284|||3|||ENSP00000462558||J3KSM5|UPI000268AE1F||||||||0.9418|0.9539|0.999|0.9592|0.9847|||0.9721|0.9533|0.9754|0.9166|0.9999|0.9923|0.9677|0.9536|0.9811|0.9999|gnomAD_EAS|||||||||||||||||||-27|-2|23|25|0.00|0.00|0.00|0.00|PERM1 1 979560 . T C . . CSQ=C|synonymous_variant|LOW|PERM1|ENSG00000187642|Transcript|ENST00000341290|protein_coding|3/5||ENST00000341290.6:c.1128A>G|ENSP00000343864.2:p.Ala376%3D|1164|1128|376|A|gcA/gcG|rs13303033||-1||SNV|HGNC|HGNC:28208|||2|A2||ENSP00000343864|Q5SV97||||||PANTHER:PTHR47282&Low_complexity_(Seg):seg|||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379407|protein_coding||||||||||rs13303033|4552|1||SNV|HGNC|HGNC:25284|||1|A2|CCDS53256.1|ENSP00000368717|Q494U1|||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379409|protein_coding||||||||||rs13303033|4552|1||SNV|HGNC|HGNC:25284|||2|A2||ENSP00000368719|Q494U1|||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000379410|protein_coding||||||||||rs13303033|3695|1||SNV|HGNC|HGNC:25284|YES|NM_032129.3|1|P3|CCDS4.1|ENSP00000368720|Q494U1||UPI00001416D8|||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|synonymous_variant|LOW|PERM1|ENSG00000187642|Transcript|ENST00000433179|protein_coding|1/3||ENST00000433179.3:c.1470A>G|ENSP00000414022.3:p.Ala490%3D|1470|1470|490|A|gcA/gcG|rs13303033||-1||SNV|HGNC|HGNC:28208|YES||5|P2|CCDS76083.1|ENSP00000414022|Q5SV97||||||PANTHER:PTHR47282&Low_complexity_(Seg):seg|||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|upstream_gene_variant|MODIFIER|PERM1|ENSG00000187642|Transcript|ENST00000479361|retained_intron||||||||||rs13303033|2919|-1||SNV|HGNC|HGNC:28208|||1|||||||||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1,C|downstream_gene_variant|MODIFIER|PLEKHN1|ENSG00000187583|Transcript|ENST00000491024|protein_coding||||||||||rs13303033|3695|1|cds_start_NF|SNV|HGNC|HGNC:25284|||3|||ENSP00000462558||J3KSM5|UPI000268AE1F|||||||0.5096|0.177|0.6095|0.7123|0.5895|0.5971|||0.5887|0.2428|0.6604|0.5617|0.7237|0.5334|0.5801|0.5647|0.6213|0.7237|gnomAD_EAS|||||||||||||||||||28|-30|-39|3|0.00|0.00|0.00|0.00|PERM1 1 999842 . C A . . CSQ=A|intron_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000304952|protein_coding||1/3|ENST00000304952.11:c.108+24G>T|||||||rs2298214||-1||SNV|HGNC|HGNC:24149||NM_021170.4|1|P1|CCDS5.1|ENSP00000304595|Q9HCC6|||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|missense_variant|MODERATE|HES4|ENSG00000188290|Transcript|ENST00000428771|protein_coding|1/3||ENST00000428771.6:c.132G>T|ENSP00000393198.2:p.Arg44Ser|331|132|44|R/S|agG/agT|rs2298214||-1||SNV|HGNC|HGNC:24149|YES||2||CCDS44034.1|ENSP00000393198||E9PB28|UPI0001881B51||tolerated_low_confidence(0.72)|benign(0)|MobiDB_lite:mobidb-lite&Low_complexity_(Seg):seg|||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS||||||||||||||||||MUTANT_DONOR_MES:11.0784944978449&EXON_END:1000172&INTRON_END:999691&DE_NOVO_DONOR_MES_POS:-156&DE_NOVO_DONOR_POS:-156&EXON_START:999692&DE_NOVO_DONOR_MES:7.0006176073036&DE_NOVO_DONOR_PROB:0.167156964545091&INTRON_START:999614|6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|non_coding_transcript_exon_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000481869|retained_intron|1/2||ENST00000481869.1:n.255G>T||255|||||rs2298214||-1||SNV|HGNC|HGNC:24149|||2|||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|intron_variant|MODIFIER|HES4|ENSG00000188290|Transcript|ENST00000484667|protein_coding||1/2|ENST00000484667.2:c.108+24G>T|||||||rs2298214||-1||SNV|HGNC|HGNC:24149|||3|||ENSP00000425085||D6REB3|UPI0001D3BBEE|||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|AL645608.7|ENSG00000272512|Transcript|ENST00000606034|lncRNA||||||||||rs2298214|1791|-1||SNV|Clone_based_ensembl_gene||YES|||||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|ISG15|ENSG00000187608|Transcript|ENST00000624652|protein_coding||||||||||rs2298214|1303|1|cds_end_NF|SNV|HGNC|HGNC:4053|||3|||ENSP00000485313||A0A096LNZ9||1||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|upstream_gene_variant|MODIFIER|ISG15|ENSG00000187608|Transcript|ENST00000624697|protein_coding||||||||||rs2298214|1296|1||SNV|HGNC|HGNC:4053|||3|A2||ENSP00000485643||A0A096LPJ4||1||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS|||||||||||||||||||6|-37|6|24|0.00|0.00|0.01|0.02|HES4,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000118|promoter||||||||||rs2298214||||SNV||||||||||||||||||0.4938|0.0356|0.6268|0.7718|0.5895|0.6339|0.1386|0.5695|0.6136|0.1208|0.7139|0.6344|0.786|0.5555|0.595|0.5882|0.6625|0.786|gnomAD_EAS||||||||||||||||||||||||||| 1 12716215 . C A . . CSQ=A|stop_gained|HIGH|AADACL3|ENSG00000188984|Transcript|ENST00000359318|protein_coding|1/4||ENST00000359318.8:c.39C>A|ENSP00000352268.6:p.Cys13Ter|106|39|13|C/*|tgC/tgA|rs3000860||1||SNV|HGNC|HGNC:32037|YES|NM_001103170.3|3|P1|CCDS41253.2|ENSP00000352268|Q5VUY0||UPI0003EAEC70||||PIRSF:PIRSF037251&PANTHER:PTHR23024&PANTHER:PTHR23024:SF115&Transmembrane_helices:TMhelix|||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||HC|||GERP_DIST:92.57575&BP_DIST:1182&PERCENTILE:0.0318627450980392&DIST_FROM_LAST_EXON:408&50_BP_RULE:PASS&PHYLOCSF_TOO_SHORT|||||||||,A|non_coding_transcript_exon_variant|MODIFIER|AADACL3|ENSG00000188984|Transcript|ENST00000620146|processed_transcript|1/3||ENST00000620146.2:n.101C>A||101|||||rs3000860||1||SNV|HGNC|HGNC:32037|||2|||||||||||||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS|||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000347677|promoter_flanking_region||||||||||rs3000860||||SNV||||||||||||||||||0.1436|0.1188|0.1052|0.2679|0.1362|0.0838||||||||||||0.2679|EAS||||||||||||||||||||||||||| bcftools-1.21/test/split-vep.7.out000066400000000000000000000002051467060157400170570ustar00rootroot0000000000000014464 non_coding_transcript_exon_variant 14469 non_coding_transcript_exon_variant 14522 intron_variant&non_coding_transcript_variant bcftools-1.21/test/split-vep.7.vcf000066400000000000000000000046441467060157400170410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##FORMAT= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG001 chr1 817186 . G A 50 PASS ANN=A|upstream_gene_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lncRNA||||||||||rs3094315|185|1||SNV|HGNC|HGNC:32236|YES||2||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|AL669831.4|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||1/4|ENST00000447500.4:n.340+187C>T|||||||rs3094315||-1||SNV|Clone_based_ensembl_gene||YES||5||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|AL669831.3|ENSG00000230021|Transcript|ENST00000634337|processed_transcript||1/4|ENST00000634337.2:n.127+10484C>T|||||||rs3094315||-1||SNV|Clone_based_ensembl_gene||||5||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|AL669831.3|ENSG00000230021|Transcript|ENST00000635509|processed_transcript||1/3|ENST00000635509.2:n.100+10484C>T|||||||rs3094315||-1||SNV|Clone_based_ensembl_gene||||5||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721|||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000085|promoter||||||||||rs3094315||||SNV|||||||||||||||||||0.3873|0.804|0.8839|0.84|0.8088||||||||||||0.8839|EAS||||21159730&21492446&23664118&19096721||||| GT 1|1 bcftools-1.21/test/split-vep.8.out000066400000000000000000000002431467060157400170620ustar00rootroot0000000000000014464 SMPLB 0/1 non_coding_transcript_exon_variant 14469 SMPLB 0/1 non_coding_transcript_exon_variant 14522 SMPLB 0/1 intron_variant&non_coding_transcript_variant bcftools-1.21/test/split-vep.8.vcf000066400000000000000000000017541467060157400170410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 145075172 . G A . . BCSQ=intron|PDE4DIP||protein_coding,non_coding|PDE4DIP||retained_intron,non_coding|PDE4DIP||processed_transcript,intron|PDE4DIP||NMD 2 175216515 . A G . . BCSQ=intron|CIR1||protein_coding,non_coding|CIR1||retained_intron 20 37400393 . C T . . BCSQ=synonymous|ACTR5|ENST00000243903|protein_coding|+|586S|37400393C>T X 48822646 . T G . . BCSQ=missense|KCND1|ENST00000376477|protein_coding|-|135T>135P|48822646T>G,missense|KCND1|ENST00000218176|protein_coding|-|512T>512P|48822646T>G,missense|KCND1|ENST00000419374|protein_coding|-|83T>83P|48822646T>G bcftools-1.21/test/split-vep.9.out000066400000000000000000000003711467060157400170650ustar00rootroot0000000000000014464 .,YES,YES,.,.,.,. non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,downstream_gene_variant,non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,non_coding_transcript_exon_variant,regulatory_region_variant bcftools-1.21/test/split-vep.9.vcf000066400000000000000000000011751467060157400170370ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 145075172 . G A . . AF=1;BCSQ=intron|PDE4DIP||protein_coding||||111|2 bcftools-1.21/test/split-vep.broken-LoF.2.out000066400000000000000000000022541467060157400210150ustar00rootroot00000000000000chr21:5032064 PERCENTILE:0.773118279569892/GERP_DIST:-366.377766615897/BP_DIST:218/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 PERCENTILE:0.635578583765112/GERP_DIST:-366.377766615897/BP_DIST:218/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 PERCENTILE:0.659498207885305/GERP_DIST:-372.525567065179/BP_DIST:197/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 PERCENTILE:0.790979097909791/GERP_DIST:-372.525567065179/BP_DIST:197/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 PERCENTILE:0.790979097909791/GERP_DIST:-372.525567065179/BP_DIST:197/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT chr21:5032064 PERCENTILE:0.463571889103804/GERP_DIST:-1141.14512844086/BP_DIST:840/DIST_FROM_LAST_EXON:152/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT chr21:5032064 PERCENTILE:0.662062615101289/GERP_DIST:-354.294564935565/BP_DIST:374/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT chr21:5032064 PERCENTILE:0.785792349726776/GERP_DIST:-391.862466733158/BP_DIST:203/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT bcftools-1.21/test/split-vep.broken-LoF.out000066400000000000000000000033021467060157400206500ustar00rootroot00000000000000chr21:5032064 missense_variant . chr21:5032064 missense_variant . chr21:5032064 missense_variant . chr21:5032064 3_prime_UTR_variant&NMD_transcript_variant . chr21:5032064 missense_variant . chr21:5032064 missense_variant . chr21:5032064 missense_variant . chr21:5032064 missense_variant . chr21:5032064 missense_variant . chr21:5032064 frameshift_variant PERCENTILE:0.773118279569892/GERP_DIST:-366.377766615897/BP_DIST:218/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 frameshift_variant PERCENTILE:0.635578583765112/GERP_DIST:-366.377766615897/BP_DIST:218/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 frameshift_variant PERCENTILE:0.659498207885305/GERP_DIST:-372.525567065179/BP_DIST:197/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 3_prime_UTR_variant&NMD_transcript_variant . chr21:5032064 frameshift_variant PERCENTILE:0.790979097909791/GERP_DIST:-372.525567065179/BP_DIST:197/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/ANN_ORF:-698.745/MAX_ORF:-698.745 chr21:5032064 frameshift_variant PERCENTILE:0.790979097909791/GERP_DIST:-372.525567065179/BP_DIST:197/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT chr21:5032064 frameshift_variant PERCENTILE:0.463571889103804/GERP_DIST:-1141.14512844086/BP_DIST:840/DIST_FROM_LAST_EXON:152/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT chr21:5032064 frameshift_variant PERCENTILE:0.662062615101289/GERP_DIST:-354.294564935565/BP_DIST:374/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT chr21:5032064 frameshift_variant PERCENTILE:0.785792349726776/GERP_DIST:-391.862466733158/BP_DIST:203/DIST_FROM_LAST_EXON:187/50_BP_RULE:PASS/PHYLOCSF_TOO_SHORT bcftools-1.21/test/split-vep.broken-LoF.vcf000066400000000000000000000152061467060157400206250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr21 5032064 . G A . . vep=A|missense_variant|MODERATE|FP565260.3|ENSG00000277117|Transcript|ENST00000612610|protein_coding|5/7||ENST00000612610.4:c.709G>A|ENSP00000483732.1:p.Gly237Arg|896|709|237|G/R|Gga/Aga|1||1|SNV||Clone_based_ensembl_gene|||1|A2||ENSP00000483732|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|||||||||,A|missense_variant|MODERATE|FP565260.3|ENSG00000277117|Transcript|ENST00000620481|protein_coding|4/6||ENST00000620481.4:c.358G>A|ENSP00000484302.1:p.Gly120Arg|545|358|120|G/R|Gga/Aga|1||1|SNV||Clone_based_ensembl_gene|||5|||ENSP00000484302|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|||||||||,A|missense_variant|MODERATE|FP565260.3|ENSG00000277117|Transcript|ENST00000623795|protein_coding|4/6||ENST00000623795.1:c.358G>A|ENSP00000485649.1:p.Gly120Arg|505|358|120|G/R|Gga/Aga|1||1|SNV||Clone_based_ensembl_gene|||2|||ENSP00000485649|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|||||||||,A|3_prime_UTR_variant&NMD_transcript_variant|MODIFIER|FP565260.3|ENSG00000277117|Transcript|ENST00000623903|nonsense_mediated_decay|5/7||ENST00000623903.3:c.*323G>A||706|||||1||1|SNV||Clone_based_ensembl_gene|||2|||ENSP00000485557||||||||||||||||,A|missense_variant|MODERATE|FP565260.3|ENSG00000277117|Transcript|ENST00000623960|protein_coding|5/7||ENST00000623960.4:c.709G>A|ENSP00000485129.1:p.Gly237Arg|858|709|237|G/R|Gga/Aga|1||1|SNV||Clone_based_ensembl_gene||YES|1|P2|CCDS86973.1|ENSP00000485129|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|||||||||,A|missense_variant|MODERATE|LOC102723996|102723996|Transcript|NM_001363770.2|protein_coding|5/7||NM_001363770.2:c.709G>A|NP_001350699.1:p.Gly237Arg|858|709|237|G/R|Gga/Aga|1||1|SNV||EntrezGene||YES||||NP_001350699.1||||||||||||||||,A|missense_variant|MODERATE|LOC102723996|102723996|Transcript|XM_006723899.2|protein_coding|5/6||XM_006723899.2:c.709G>A|XP_006723962.1:p.Gly237Arg|1345|709|237|G/R|Gga/Aga|1||1|SNV||EntrezGene||||||XP_006723962.1||||||||||||||||,A|missense_variant|MODERATE|LOC102723996|102723996|Transcript|XM_011546078.2|protein_coding|5/7||XM_011546078.2:c.709G>A|XP_011544380.1:p.Gly237Arg|1345|709|237|G/R|Gga/Aga|1||1|SNV||EntrezGene||||||XP_011544380.1||||||||||||||||,A|missense_variant|MODERATE|LOC102723996|102723996|Transcript|XM_011546079.1|protein_coding|5/7||XM_011546079.1:c.709G>A|XP_011544381.1:p.Gly237Arg|1345|709|237|G/R|Gga/Aga|1||1|SNV||EntrezGene||||||XP_011544381.1|||||||||||||||| chr21 5032064 . G GGA . . vep=GA|frameshift_variant|HIGH|FP565260.3|ENSG00000277117|Transcript|ENST00000612610|protein_coding|5/7||ENST00000612610.4:c.718_719dup|ENSP00000483732.1:p.Asp240GlufsTer35|896-897|709-710|237|G/GX|gga/gGAga|1||1|insertion||Clone_based_ensembl_gene|||1|A2||ENSP00000483732|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|10|||||HC||PHYLOCSF_WEAK|PERCENTILE:0.773118279569892,GERP_DIST:-366.377766615897,BP_DIST:218,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,ANN_ORF:-698.745,MAX_ORF:-698.745,GA|frameshift_variant|HIGH|FP565260.3|ENSG00000277117|Transcript|ENST00000620481|protein_coding|4/6||ENST00000620481.4:c.367_368dup|ENSP00000484302.1:p.Asp123GlufsTer35|545-546|358-359|120|G/GX|gga/gGAga|1||1|insertion||Clone_based_ensembl_gene|||5|||ENSP00000484302|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|10|||||HC||PHYLOCSF_WEAK|PERCENTILE:0.635578583765112,GERP_DIST:-366.377766615897,BP_DIST:218,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,ANN_ORF:-698.745,MAX_ORF:-698.745,GA|frameshift_variant|HIGH|FP565260.3|ENSG00000277117|Transcript|ENST00000623795|protein_coding|4/6||ENST00000623795.1:c.367_368dup|ENSP00000485649.1:p.Asp123GlufsTer35|505-506|358-359|120|G/GX|gga/gGAga|1||1|insertion||Clone_based_ensembl_gene|||2|||ENSP00000485649|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|10|||||HC||PHYLOCSF_WEAK|PERCENTILE:0.659498207885305,GERP_DIST:-372.525567065179,BP_DIST:197,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,ANN_ORF:-698.745,MAX_ORF:-698.745,GA|3_prime_UTR_variant&NMD_transcript_variant|MODIFIER|FP565260.3|ENSG00000277117|Transcript|ENST00000623903|nonsense_mediated_decay|5/7||ENST00000623903.3:c.*332_*333dup||706-707|||||1||1|insertion||Clone_based_ensembl_gene|||2|||ENSP00000485557||||||||||||||||,GA|frameshift_variant|HIGH|FP565260.3|ENSG00000277117|Transcript|ENST00000623960|protein_coding|5/7||ENST00000623960.4:c.718_719dup|ENSP00000485129.1:p.Asp240GlufsTer35|858-859|709-710|237|G/GX|gga/gGAga|1||1|insertion||Clone_based_ensembl_gene||YES|1|P2|CCDS86973.1|ENSP00000485129|||||||PANTHER:PTHR24100&PANTHER:PTHR24100|10|||||HC||PHYLOCSF_WEAK|PERCENTILE:0.790979097909791,GERP_DIST:-372.525567065179,BP_DIST:197,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,ANN_ORF:-698.745,MAX_ORF:-698.745,GA|frameshift_variant|HIGH|LOC102723996|102723996|Transcript|NM_001363770.2|protein_coding|5/7||NM_001363770.2:c.718_719dup|NP_001350699.1:p.Asp240GlufsTer35|858-859|709-710|237|G/GX|gga/gGAga|1||1|insertion||EntrezGene||YES||||NP_001350699.1||||||||10|||||HC|||PERCENTILE:0.790979097909791,GERP_DIST:-372.525567065179,BP_DIST:197,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,PHYLOCSF_TOO_SHORT,GA|frameshift_variant|HIGH|LOC102723996|102723996|Transcript|XM_006723899.2|protein_coding|5/6||XM_006723899.2:c.718_719dup|XP_006723962.1:p.Asp240GlufsTer35|1345-1346|709-710|237|G/GX|gga/gGAga|1||1|insertion||EntrezGene||||||XP_006723962.1||||||||10|||||HC|||PERCENTILE:0.463571889103804,GERP_DIST:-1141.14512844086,BP_DIST:840,DIST_FROM_LAST_EXON:152,50_BP_RULE:PASS,PHYLOCSF_TOO_SHORT,GA|frameshift_variant|HIGH|LOC102723996|102723996|Transcript|XM_011546078.2|protein_coding|5/7||XM_011546078.2:c.718_719dup|XP_011544380.1:p.Asp240GlufsTer35|1345-1346|709-710|237|G/GX|gga/gGAga|1||1|insertion||EntrezGene||||||XP_011544380.1||||||||10|||||HC|||PERCENTILE:0.662062615101289,GERP_DIST:-354.294564935565,BP_DIST:374,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,PHYLOCSF_TOO_SHORT,GA|frameshift_variant|HIGH|LOC102723996|102723996|Transcript|XM_011546079.1|protein_coding|5/7||XM_011546079.1:c.718_719dup|XP_011544381.1:p.Asp240GlufsTer35|1345-1346|709-710|237|G/GX|gga/gGAga|1||1|insertion||EntrezGene||||||XP_011544381.1||||||||10|||||HC|||PERCENTILE:0.785792349726776,GERP_DIST:-391.862466733158,BP_DIST:203,DIST_FROM_LAST_EXON:187,50_BP_RULE:PASS,PHYLOCSF_TOO_SHORT bcftools-1.21/test/split-vep.filter-missing-bt2098.1.out000066400000000000000000000001461467060157400227360ustar00rootroot00000000000000chr1 97630165 .,. chr1 116938163 0.015909,0.015909,0.015909,0.015909 chr1 132003572 .,.,.,.,.,. bcftools-1.21/test/split-vep.filter-missing-bt2098.vcf000066400000000000000000000122531467060157400225500ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 97630165 . T C . . CSQ=C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00001141396|enhancer||||||||||rs1480440198|1||||1|SNV|||||||||||||||||||||||||||||||||||||||||||||||||||||||8.208|0.673305|8.208|0.673305|||||||||||||||||||||,C|intergenic_variant|MODIFIER|||||||||||||||rs1480440198|1|||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||||||8.208|0.673305|8.208|0.673305||||||||||||||||||||| chr1 116938163 . G C . . CSQ=C|upstream_gene_variant|MODIFIER|AARD|ENSG00000205002|Transcript|ENST00000378279|protein_coding||||||||||rs1554616421|1|44|1||1|SNV|HGNC|HGNC:33842|YES|1|CCDS34935.1|ENSP00000367528|Q4LEZ3.97||UPI0000419472||NM_001025357.3||||||||||||||||||||||0.0002334|0.0001014|0|0.0001398|0|0.001988|0.0003349|0|0.0001708|0|0.001303|0.001988|gnomADg_EAS||||||||||7.584|0.607429|7.584|0.607429|||||||||||||||||rs1554616421|0.015909|6316|397018|19,C|upstream_gene_variant|MODIFIER|AARD|ENSG00000205002|Transcript|ENST00000523536|protein_coding_CDS_not_defined||||||||||rs1554616421|1|383|1|||SNV|HGNC|HGNC:33842||3|||||||||||||||||||||||||||||0.0002334|0.0001014|0|0.0001398|0|0.001988|0.0003349|0|0.0001708|0|0.001303|0.001988|gnomADg_EAS||||||||||7.584|0.607429|7.584|0.607429|||||||||||||||||rs1554616421|0.015909|6316|397018|19,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000229087|promoter||||||||||rs1554616421|1|||||SNV|||||||||||||||||||||||||||||||||0.0002334|0.0001014|0|0.0001398|0|0.001988|0.0003349|0|0.0001708|0|0.001303|0.001988|gnomADg_EAS||||||||||7.584|0.607429|7.584|0.607429|||||||||||||||||rs1554616421|0.015909|6316|397018|19,C|TF_binding_site_variant|MODIFIER|||MotifFeature|ENSM00198861829|||||||||||rs1554616421|1||1|||SNV|||||||||||||||||||||||||||||||||0.0002334|0.0001014|0|0.0001398|0|0.001988|0.0003349|0|0.0001708|0|0.001303|0.001988|gnomADg_EAS|||||ENSPFM0086|10|Y|-0.058|EGR1&EGR2&EGR4&EGR3|7.584|0.607429|7.584|0.607429|||||||||||||||||rs1554616421|0.015909|6316|397018|19 chr1 132003572 . A G . . CSQ=G|intron_variant|MODIFIER|EFR3A|ENSG00000132294|Transcript|ENST00000254624|protein_coding||22/22|ENST00000254624.10:c.2360+287A>G||||||||1||1||1|SNV|HGNC|HGNC:28970|YES|1|CCDS34942.2|ENSP00000254624|Q14156.161||UPI00001C1E8F|Q14156-1|NM_001323558.2&NM_015137.6||||||||||||||||||||||||||||||||||||||||||||5.137|0.374079|5.137|0.374079|||||||||||||||||||||,G|intron_variant|MODIFIER|EFR3A|ENSG00000132294|Transcript|ENST00000519656|protein_coding||22/22|ENST00000519656.1:c.2252+287A>G||||||||1||1|||SNV|HGNC|HGNC:28970||1|CCDS83328.1|ENSP00000428086|Q14156.161||UPI0000D62503|Q14156-2|NM_001323555.2&NM_001323554.2&NM_001323553.2&NM_001323557.2&NM_001323556.2||||||||||||||||||||||||||||||||||||||||||||5.137|0.374079|5.137|0.374079|||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|EFR3A|ENSG00000132294|Transcript|ENST00000519920|protein_coding_CDS_not_defined|||||||||||1|2616|1|||SNV|HGNC|HGNC:28970||5|||||||||||||||||||||||||||||||||||||||||||||||||||5.137|0.374079|5.137|0.374079|||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|EFR3A|ENSG00000132294|Transcript|ENST00000521940|protein_coding_CDS_not_defined||4/4|ENST00000521940.1:n.447+287A>G||||||||1||1|||SNV|HGNC|HGNC:28970||3|||||||||||||||||||||||||||||||||||||||||||||||||||5.137|0.374079|5.137|0.374079|||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|EFR3A|ENSG00000132294|Transcript|ENST00000523074|retained_intron||5/5|ENST00000523074.5:n.541+287A>G||||||||1||1|||SNV|HGNC|HGNC:28970||3|||||||||||||||||||||||||||||||||||||||||||||||||||5.137|0.374079|5.137|0.374079|||||||||||||||||||||,G|intron_variant|MODIFIER|EFR3A|ENSG00000132294|Transcript|ENST00000637848|protein_coding||22/22|ENST00000637848.1:c.2441+287A>G||||||||1||1|||SNV|HGNC|HGNC:28970||5||ENSP00000490312||A0A1B0GUZ7.35|UPI0007E52B5F||||||||||||||||||||||||||||||||||||||||||||||5.137|0.374079|5.137|0.374079||||||||||||||||||||| bcftools-1.21/test/split-vep.filter.1.out000066400000000000000000000001341467060157400203360ustar00rootroot0000000000000041334153 5_prime_utr_variant&nmd_transcript_variant ENST00000478993 nonsense_mediated_decay bcftools-1.21/test/split-vep.filter.2.out000066400000000000000000000012751467060157400203460ustar00rootroot0000000000000041334153 5_prime_utr_variant&nmd_transcript_variant ENST00000478993 nonsense_mediated_decay A|5_prime_UTR_variant&NMD_transcript_variant|MODIFIER|DDX3X|ENSG00000215301|Transcript|ENST00000478993|nonsense_mediated_decay|1/19||ENST00000478993.5:c.-100G>A||756||||||1||1||SNV|HGNC|HGNC:2745|||1||CCDS43931.1|ENSP00000478443|O00571.228||UPI000013CB6D|O00571-1|1|||||||||||||||||||||||||||||||||||loss/donor/41334153-41334154/Medium/1.787081|0|0|2|uAUG_gained_CapDistanceToStart:755&uAUG_gained_DistanceToCDS:100&uAUG_gained_DistanceToStop:27&uAUG_gained_KozakContext:GCGATGC&uAUG_gained_KozakStrength:Moderate&uAUG_gained_type:uORF|uAUG_gained|15.55|1.471728||||||-27|11|-27|-25|0.01|0.00|0.00|0.00|DDX3X bcftools-1.21/test/split-vep.filter.vcf000066400000000000000000000056371467060157400201630ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##VEP="v102" time="2020-12-14 19:43:49" cache="/opt/vep/.vep/homo_sapiens/102_GRCh38" ensembl-variation=102.2716d2e ensembl-io=102.ff1cf96 ensembl-funcgen=102.6bd93a0 ensembl=102.347f9ed 1000genomes="phase3" COSMIC="91" ClinVar="202006" ESP="V2-SSA137" HGMD-PUBLIC="20194" assembly="GRCh38.p13" dbSNP="153" gencode="GENCODE 36" genebuild="2014-07" gnomAD="r2.1" polyphen="2.2.2" regbuild="1.0" sift="sift5.2.2" ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO chrX 41334153 . G A . . CSQ=A|5_prime_UTR_variant&NMD_transcript_variant|MODIFIER|DDX3X|ENSG00000215301|Transcript|ENST00000478993|nonsense_mediated_decay|1/19||ENST00000478993.5:c.-100G>A||756||||||1||1||SNV|HGNC|HGNC:2745|||1||CCDS43931.1|ENSP00000478443|O00571.228||UPI000013CB6D|O00571-1|1|||||||||||||||||||||||||||||||||||loss/donor/41334153-41334154/Medium/1.787081|0|0|2|uAUG_gained_CapDistanceToStart:755&uAUG_gained_DistanceToCDS:100&uAUG_gained_DistanceToStop:27&uAUG_gained_KozakContext:GCGATGC&uAUG_gained_KozakStrength:Moderate&uAUG_gained_type:uORF|uAUG_gained|15.55|1.471728||||||-27|11|-27|-25|0.01|0.00|0.00|0.00|DDX3X chrX 41334585 . GGACGCGCATGCGC G . . CSQ=-|intron_variant|MODIFIER|DDX3X|ENSG00000215301|Transcript|ENST00000457138|protein_coding||1/15|ENST00000457138.7:c.45+291_45+303del||||||||1||1||deletion|HGNC|HGNC:2745|||2||CCDS55404.1|ENSP00000392494|O00571.228||UPI00017A8655|O00571-2|1||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&NMD_transcript_variant|MODIFIER|DDX3X|ENSG00000215301|Transcript|ENST00000478993|nonsense_mediated_decay||1/18|ENST00000478993.5:c.45+291_45+303del||||||||1||1||deletion|HGNC|HGNC:2745|||1||CCDS43931.1|ENSP00000478443|O00571.228||UPI000013CB6D|O00571-1|1|||||||||||||||||||||||||||||||||||||||||||||||||||||||| bcftools-1.21/test/split-vep.gene-list.1.out000066400000000000000000000010201467060157400207330ustar00rootroot000000000000001:1000 ENSG00000082996 missense_variant 1:1000 ENSG00000206199 splice_acceptor_variant&non_coding_transcript_variant 1:2000 ENSG00000104936 downstream_gene_variant 1:2000 ENSG00000177045 missense_variant 1:2000 ENSG00000237452 downstream_gene_variant 1:2000 ENSG00000267395 upstream_gene_variant 1:3000 ENSG00000285314 splice_donor_variant&non_coding_transcript_variant 1:3000 ENSG00000099949 splice_donor_variant&non_coding_transcript_variant 1:4000 ENSG00000013563 splice_donor_variant 1:4000 ENSG00000147403 missense_variant bcftools-1.21/test/split-vep.gene-list.2.out000066400000000000000000000001701467060157400207410ustar00rootroot000000000000001:1000 ENSG00000082996 missense_variant 1:2000 ENSG00000177045 missense_variant 1:4000 ENSG00000147403 missense_variant bcftools-1.21/test/split-vep.gene-list.3.out000066400000000000000000000004141467060157400207430ustar00rootroot000000000000001:1000 ENSG00000082996 missense_variant 1:2000 ENSG00000177045 missense_variant 1:3000 ENSG00000285314 splice_donor_variant&non_coding_transcript_variant 1:3000 ENSG00000099949 splice_donor_variant&non_coding_transcript_variant 1:4000 ENSG00000147403 missense_variant bcftools-1.21/test/split-vep.gene-list.txt000066400000000000000000000000211467060157400206040ustar00rootroot00000000000000RNF13 SIX5 RPL10 bcftools-1.21/test/split-vep.gene-list.vcf000066400000000000000000000144731467060157400205630ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1000 . C T . . CSQ=T|missense_variant|MODERATE|RNF13|ENSG00000082996|Transcript|ENST00000344229|protein_coding|3/11||ENST00000344229.7:c.92C>T|ENSP00000341361.3:p.Pro31Leu|794|92|31|P/L|cCt/cTt||1||1||SNV|HGNC|HGNC:10057||||1|P1|CCDS3146.1|ENSP00000341361|O43567.157||UPI0000134318|O43567-1|1|tolerated(0.09)|benign(0.007)|CDD:cd02123&PANTHER:PTHR22765:SF34&PANTHER:PTHR22765&Gene3D:3.50.30.30||||||||||||||||||||||||||||||||||||||27.4|4.062662|ENST00000392894&ENST00000344229&ENST00000470151&ENST00000466478&ENST00000468648&ENST00000459632&ENST00000466795&ENST00000490631|D|D&D|B&B&.&.&.&.&.&.|B&B&.&.&.&.&.&.|T&T&D&D&T&D&D&T|O43567&O43567&C9JYY4&C9JU37&C9JRV0&C9JYN7&C9J8T4&C9J383|.&YES&.&.&.&.&.&.|||||0.323|9|6|31|22|0.00|0.00|0.00|0.00|RNF13,T|splice_acceptor_variant&non_coding_transcript_variant|HIGH|ANKUB1|ENSG00000206199|Transcript|ENST00000473672|processed_transcript||1/1|ENST00000473672.1:n.487-1G>A||||||||1||-1||SNV|HGNC|HGNC:29642||||4||||||||||||||||||||||||||||||||||||||||||extended_intronic_splice_region_variant|loss/acceptor/149846117-149846118/Medium/6.247071||||||27.4|4.062662||||||||||||||9|6|31|22|0.00|0.00|0.00|0.00|RNF13 1 2000 . G A . . CSQ=A|downstream_gene_variant|MODIFIER|DMPK|ENSG00000104936|Transcript|ENST00000291270|protein_coding||||||||||rs767172612|1|886|-1||SNV|HGNC|HGNC:2933|YES|NM_004409.5||5|A2|CCDS12674.1|ENSP00000291270|Q09013.209|E5KR06.76|UPI0000223FEB|Q09013-9|1||||||||||||||3.968e-05|0|0|0|9.843e-05|0|0|0|0.0001825|0.0001825|gnomAD_SAS|||||||||||||||||24.5|3.428627||||||||||||||-13|-38|24|-11|0.00|0.00|0.00|0.00|SIX5,A|missense_variant|MODERATE|SIX5|ENSG00000177045|Transcript|ENST00000317578|protein_coding|1/3||ENST00000317578.7:c.14C>T|ENSP00000316842.4:p.Pro5Leu|422|14|5|P/L|cCt/cTt|rs767172612|1||-1||SNV|HGNC|HGNC:10891|YES|NM_175875.5||1|P1|CCDS12673.1|ENSP00000316842|Q8N196.159||UPI0000366E2B||1|deleterious_low_confidence(0)|benign(0.093)|PANTHER:PTHR10390&PANTHER:PTHR10390:SF40&MobiDB_lite:mobidb-lite&Low_complexity_(Seg):seg|||||||||||3.968e-05|0|0|0|9.843e-05|0|0|0|0.0001825|0.0001825|gnomAD_SAS|||||||||||||||||24.5|3.428627|ENST00000643139&ENST00000317578&ENST00000622857&ENST00000560168||D|B&B&.&.|B&B&.&.|.&D&.&.|Q8N196&Q8N196&A0A087WXX3&H0YLF6|.&YES&.&.|||||0.405|-13|-38|24|-11|0.00|0.00|0.00|0.00|SIX5,A|downstream_gene_variant|MODIFIER|MEIOSIN|ENSG00000237452|Transcript|ENST00000457052|protein_coding||||||||||rs767172612|1|4290|1||SNV|HGNC|HGNC:44318|YES|NM_001310124.2||5|P1|CCDS82368.1|ENSP00000402674|C9JSJ3.79||UPI0002840CC6||||||||||||||||3.968e-05|0|0|0|9.843e-05|0|0|0|0.0001825|0.0001825|gnomAD_SAS|||||||||||||||||24.5|3.428627||||||||||||||-13|-38|24|-11|0.00|0.00|0.00|0.00|SIX5,A|upstream_gene_variant|MODIFIER|DM1-AS|ENSG00000267395|Transcript|ENST00000586251|lncRNA||||||||||rs767172612|1|2151|1||SNV|HGNC|HGNC:53125||||2||||||||||||||||||||||3.968e-05|0|0|0|9.843e-05|0|0|0|0.0001825|0.0001825|gnomAD_SAS|||||||||||||||||24.5|3.428627||||||||||||||-13|-38|24|-11|0.00|0.00|0.00|0.00|SIX5 1 3000 . G T . . CSQ=T|splice_donor_variant&non_coding_transcript_variant|HIGH||ENSG00000285314|Transcript|ENST00000479606|lncRNA||11/21|ENST00000479606.5:n.1295+1G>T|||||||rs767191322&COSV53149291|1||1||SNV|||YES|||2||||||||||||||||||||||4.057e-06|0|0|0|0|0|8.998e-06|0|0|8.998e-06|gnomAD_NFE||0&1|1&1|||||||extended_intronic_splice_region_variant|loss/donor/20992370-20992371/Medium/6.672249||||||33|5.100843||||||||||||||46|-29|45|-1|0.00|0.00|0.42|1.00|LZTR1,T|splice_donor_variant&non_coding_transcript_variant|HIGH|LZTR1|ENSG00000099949|Transcript|ENST00000492480|retained_intron||2/5|ENST00000492480.1:n.205+1G>T|||||||rs767191322&COSV53149291|1||1||SNV|HGNC|HGNC:6742||||3||||||||1||||||||||||||4.057e-06|0|0|0|0|0|8.998e-06|0|0|8.998e-06|gnomAD_NFE||0&1|1&1|||||||extended_intronic_splice_region_variant|loss/donor/20992370-20992371/Medium/6.672249||||||33|5.100843||||||||||||||46|-29|45|-1|0.00|0.00|0.42|1.00|LZTR1 1 4000 . C G . . CSQ=G|splice_donor_variant|HIGH|DNASE1L1|ENSG00000013563|Transcript|ENST00000014935|protein_coding||7/8|ENST00000014935.7:c.525+1G>C||||||||1||-1||SNV|HGNC|HGNC:2957||||2|P1|CCDS14747.1|ENSP00000014935|P49184.181||UPI0000129891||||||||||||||||||||||||||||||||||||extended_intronic_splice_region_variant|loss/donor/154403268-154403269/Medium/9.500494||||||24.2|3.326590|||||||||HC|||INTRON_SIZE:78||-23|24|25|1|0.00|0.06|0.00|0.99|DNASE1L1,G|missense_variant|MODERATE|RPL10|ENSG00000147403|Transcript|ENST00000451365|protein_coding|4/4||ENST00000451365.1:c.284C>G|ENSP00000406125.1:p.Thr95Ser|284|284|95|T/S|aCc/aGc||1||1|cds_start_NF|SNV|HGNC|HGNC:10298||||1|||ENSP00000406125||B8A6G2.66|UPI000173A19B||1|tolerated_low_confidence(0.2)|possibly_damaging(0.722)|Gene3D:3.90.1170.10||||||||||||||||||||||||||||||||||||||24.2|3.326590|ENST00000393638&ENST00000369809&ENST00000369807&ENST00000369808&ENST00000014935&ENST00000309585&ENST00000451865||D&D&D&D&D&D|.&.&.&.&.&.&.|.&.&.&.&.&.&.|.&.&.&.&.&.&.|P49184&P49184&P49184&P49184&P49184&P49184&A6QRJ0|.&YES&.&.&.&.&.|||||0.444|-23|24|25|1|0.00|0.06|0.00|0.99|DNASE1L1 bcftools-1.21/test/split-vep.mixed-list.txt000066400000000000000000000000461467060157400210030ustar00rootroot00000000000000ENST00000344229 ENST00000317578 RPL10 bcftools-1.21/test/split-vep.select-tr-expr.vcf000066400000000000000000001344521467060157400215520ustar00rootroot00000000000000##fileformat=VCFv4.1 ##VEP="v110" time="2023-11-23 11:29:25" cache="/opt/vep/.vep/homo_sapiens/110_GRCh38" ensembl-funcgen=110.24e6da6 ensembl=110.584a8f3 ensembl-variation=110.d34d25e ensembl-io=110.b1a0d57 1000genomes="phase3" COSMIC="97" ClinVar="202301" HGMD-PUBLIC="20204" assembly="GRCh38.p14" dbSNP="154" gencode="GENCODE 44" genebuild="2014-07" gnomADe="r2.1.1" gnomADg="v3.1.2" polyphen="2.2.3" regbuild="1.0" sift="6.2.1" ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1000000 . T C . . CSQ=C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000378609|protein_coding|7/12||ENST00000378609.9:c.353A>G|ENSP00000367872.3:p.Asp118Gly|716|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||1|P1|CCDS34.1|ENSP00000367872|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0)|||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1|| 1 1529299 . C T . . CSQ=T|3_prime_UTR_variant&NMD_transcript_variant|MODIFIER|ATAD3A|ENSG00000197785|Transcript|ENST00000339113|nonsense_mediated_decay|16/17||ENST00000339113.9:c.*1128C>T||1546|||||rs1057517686&CM1612408|1||1|cds_start_NF|SNV|HGNC|HGNC:25567||||2|||ENSP00000339421||H0Y2W2.57|UPI001234680D||1||||||||||||||||||||||||||||||||||pathogenic/likely_pathogenic&pathogenic||1&1||||||||||||||23.0|2.796648|||||||||||||||27640307&|0.01&0.70|HAREL-YOON_SYNDROME&ClinVar:_phenotype_not_specified|-0.180||||||33|10|36|32|0.00|0.00|0.00|0.01|ATAD3A|| 1 1789242 . T C . . CSQ=C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000378609|protein_coding|10/12||ENST00000378609.9:c.727A>G|ENSP00000367872.3:p.Thr243Ala|1090|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|YES|NM_002074.5||1|P1|CCDS34.1|ENSP00000367872|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.|||||||||0.581|-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|downstream_gene_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000434686|protein_coding||||||||||rs1394767075|1|4003|-1|cds_end_NF|SNV|HGNC|HGNC:4396||||3|||ENSP00000392765||F6UT28.70|UPI000268AE0F||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000439272|protein_coding|9/11||ENST00000439272.7:c.688A>G|ENSP00000399741.3:p.Thr230Ala|853|688|230|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5|||ENSP00000399741||F6X3N5.69|UPI0000D61E20||1|deleterious_low_confidence(0)|benign(0.094)|CDD:cd00200&PIRSF:PIRSF002394&Pfam:PF00400&Gene3D:2.130.10.10&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|non_coding_transcript_exon_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000461893|retained_intron|3/3||ENST00000461893.5:n.1183A>G||1183|||||rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||2||||||||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|non_coding_transcript_exon_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000471354|retained_intron|7/7||ENST00000471354.1:n.1331A>G||1331|||||rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5||||||||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000610897|protein_coding|9/11||ENST00000610897.4:c.727A>G|ENSP00000481878.1:p.Thr243Ala|1071|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5|P1|CCDS34.1|ENSP00000481878|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000615252|protein_coding|7/9||ENST00000615252.5:c.427A>G|ENSP00000483532.1:p.Thr143Ala|676|427|143|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396||||5||CCDS72685.1|ENSP00000483532||B3KVK2.118|UPI00002177A7||1|deleterious_low_confidence(0)|possibly_damaging(0.906)|CDD:cd00200&Pfam:PF00400&Gene3D:2.130.10.10&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50294&PROSITE_profiles:PS50082&PANTHER:PTHR19850&AlphaFold_DB_import:AF-B3KVK2-F1|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703692|protein_coding|10/11||ENST00000703692.1:c.727A>G|ENSP00000515427.1:p.Thr243Ala|950|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515427||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703693|protein_coding|14/16||ENST00000703693.1:c.727A>G|ENSP00000515428.1:p.Thr243Ala|1437|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515428||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703694|protein_coding|9/10||ENST00000703694.1:c.727A>G|ENSP00000515429.1:p.Thr243Ala|824|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515429||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|synonymous_variant&NMD_transcript_variant|LOW|GNB1|ENSG00000078369|Transcript|ENST00000703695|nonsense_mediated_decay|9/11||ENST00000703695.1:c.525A>G|ENSP00000515430.1:p.Pro175%3D|690|525|175|P|ccA/ccG|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515430|||UPI0021EC8336||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703696|protein_coding|10/12||ENST00000703696.1:c.727A>G|ENSP00000515431.1:p.Thr243Ala|972|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515431||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703697|protein_coding|10/11||ENST00000703697.1:c.727A>G|ENSP00000515432.1:p.Thr243Ala|935|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515432||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|upstream_gene_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000703698|protein_coding_CDS_not_defined||||||||||rs1394767075|1|798|-1||SNV|HGNC|HGNC:4396||||||||||||1||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703699|protein_coding|10/11||ENST00000703699.1:c.727A>G|ENSP00000515433.1:p.Thr243Ala|892|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515433||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703700|protein_coding|10/12||ENST00000703700.1:c.727A>G|ENSP00000515434.1:p.Thr243Ala|851|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515434||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703701|protein_coding|12/14||ENST00000703701.1:c.727A>G|ENSP00000515435.1:p.Thr243Ala|1231|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515435||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703702|protein_coding|11/13||ENST00000703702.1:c.727A>G|ENSP00000515436.1:p.Thr243Ala|1035|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515436||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703703|protein_coding|10/12||ENST00000703703.1:c.727A>G|ENSP00000515437.1:p.Thr243Ala|998|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515437||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703704|protein_coding|12/14||ENST00000703704.1:c.727A>G|ENSP00000515438.1:p.Thr243Ala|1259|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515438||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703705|protein_coding|9/11||ENST00000703705.1:c.595A>G|ENSP00000515439.1:p.Thr199Ala|771|595|199|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515439|||UPI0000088585||1|deleterious_low_confidence(0)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703706|protein_coding|11/13||ENST00000703706.1:c.727A>G|ENSP00000515440.1:p.Thr243Ala|1049|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515440||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703707|protein_coding|8/10||ENST00000703707.1:c.688A>G|ENSP00000515441.1:p.Thr230Ala|815|688|230|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515441|||UPI0000D61E20||1|deleterious_low_confidence(0)|benign(0.094)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703708|protein_coding|13/15||ENST00000703708.1:c.727A>G|ENSP00000515442.1:p.Thr243Ala|1364|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515442||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703709|protein_coding|11/13||ENST00000703709.1:c.727A>G|ENSP00000515443.1:p.Thr243Ala|948|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515443||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703710|protein_coding|12/14||ENST00000703710.1:c.727A>G|ENSP00000515444.1:p.Thr243Ala|1276|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515444||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703711|protein_coding|13/15||ENST00000703711.1:c.727A>G|ENSP00000515445.1:p.Thr243Ala|1257|727|243|T/A|Act/Gct|rs1394767075|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515445||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0.01)|possibly_damaging(0.906)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&PROSITE_profiles:PS50082&PROSITE_profiles:PS50294&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|P&P&P|0.89465|0.9681&0.8682&0.9703|ENST00000610897&ENST00000615252&ENST00000378609|D|D&D&D|P&.&P|P&.&P|D|0.87156|0.83386772871|.&.&D|P62873&B3KVK2&P62873|YES&.&.||||||||||-10|-26|15|-26|0.00|0.00|0.00|0.00|GNB1||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344727|CTCF_binding_site||||||||||rs1394767075|1||||SNV||||||||||||||||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00001164872|enhancer||||||||||rs1394767075|1||||SNV||||||||||||||||||||||||||1.593e-05|0|0|0|0|0|3.525e-05|0|0||||||||||||3.525e-05|gnomADe_NFE|not_provided||1||||||||||||||26.3|3.893146|||||||||||||||||||||||||||||||||| 1 1804496 . T C . . CSQ=C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000378609|protein_coding|7/12||ENST00000378609.9:c.353A>G|ENSP00000367872.3:p.Asp118Gly|716|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|YES|NM_002074.5||1|P1|CCDS34.1|ENSP00000367872|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0)|probably_damaging(0.982)||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000434686|protein_coding|8/9||ENST00000434686.6:c.353A>G|ENSP00000392765.2:p.Asp118Gly|540|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1|cds_end_NF|SNV|HGNC|HGNC:4396||||3|||ENSP00000392765||F6UT28.70|UPI000268AE0F||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&AlphaFold_DB_import:AF-F6UT28-F1&Pfam:PF00400&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|downstream_gene_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000437146|protein_coding||||||||||rs1553194162&CM1612300|1|30|-1|cds_end_NF|SNV|HGNC|HGNC:4396||||3|||ENSP00000416651||B1AKQ8.114|UPI0003F47E62||1||||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|||||||||||||||10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000439272|protein_coding|6/11||ENST00000439272.7:c.314A>G|ENSP00000399741.3:p.Asp105Gly|479|314|105|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5|||ENSP00000399741||F6X3N5.69|UPI0000D61E20||1|deleterious_low_confidence(0)|probably_damaging(0.993)|CDD:cd00200&PIRSF:PIRSF002394&Pfam:PF00400&Gene3D:2.130.10.10&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319&AlphaFold_DB_import:AF-F6X3N5-F1|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases||||||0.929|39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|non_coding_transcript_exon_variant|MODIFIER|GNB1|ENSG00000078369|Transcript|ENST00000471354|retained_intron|4/7||ENST00000471354.1:n.957A>G||957|||||rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5||||||||1||||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|||||||||||||||10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000610897|protein_coding|6/11||ENST00000610897.4:c.353A>G|ENSP00000481878.1:p.Asp118Gly|697|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5|P1|CCDS34.1|ENSP00000481878|P62873.191|A0A140VJJ8.16|UPI00000230B3|P62873-1|1|deleterious_low_confidence(0)|probably_damaging(0.982)||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000615252|protein_coding|4/9||ENST00000615252.5:c.53A>G|ENSP00000483532.1:p.Asp18Gly|302|53|18|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396||||5||CCDS72685.1|ENSP00000483532||B3KVK2.118|UPI00002177A7||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Superfamily:SSF50978&PANTHER:PTHR19850&AlphaFold_DB_import:AF-B3KVK2-F1|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703692|protein_coding|7/11||ENST00000703692.1:c.353A>G|ENSP00000515427.1:p.Asp118Gly|576|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515427||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703693|protein_coding|11/16||ENST00000703693.1:c.353A>G|ENSP00000515428.1:p.Asp118Gly|1063|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515428||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703694|protein_coding|6/10||ENST00000703694.1:c.353A>G|ENSP00000515429.1:p.Asp118Gly|450|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515429||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant&NMD_transcript_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703695|nonsense_mediated_decay|7/11||ENST00000703695.1:c.353A>G|ENSP00000515430.1:p.Asp118Gly|518|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515430|||UPI0021EC8336||1|deleterious_low_confidence(0)|probably_damaging(0.917)||||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703696|protein_coding|7/12||ENST00000703696.1:c.353A>G|ENSP00000515431.1:p.Asp118Gly|598|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515431||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703697|protein_coding|7/11||ENST00000703697.1:c.353A>G|ENSP00000515432.1:p.Asp118Gly|561|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515432||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703699|protein_coding|7/11||ENST00000703699.1:c.353A>G|ENSP00000515433.1:p.Asp118Gly|518|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515433||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703700|protein_coding|7/12||ENST00000703700.1:c.353A>G|ENSP00000515434.1:p.Asp118Gly|477|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515434||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703701|protein_coding|9/14||ENST00000703701.1:c.353A>G|ENSP00000515435.1:p.Asp118Gly|857|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515435||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703702|protein_coding|8/13||ENST00000703702.1:c.353A>G|ENSP00000515436.1:p.Asp118Gly|661|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515436||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703703|protein_coding|7/12||ENST00000703703.1:c.353A>G|ENSP00000515437.1:p.Asp118Gly|624|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515437||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703704|protein_coding|9/14||ENST00000703704.1:c.353A>G|ENSP00000515438.1:p.Asp118Gly|885|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515438||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703705|protein_coding|6/11||ENST00000703705.1:c.221A>G|ENSP00000515439.1:p.Asp74Gly|397|221|74|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515439|||UPI0000088585||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703706|protein_coding|8/13||ENST00000703706.1:c.353A>G|ENSP00000515440.1:p.Asp118Gly|675|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515440||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703707|protein_coding|5/10||ENST00000703707.1:c.314A>G|ENSP00000515441.1:p.Asp105Gly|441|314|105|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||||ENSP00000515441|||UPI0000D61E20||1|deleterious_low_confidence(0)|probably_damaging(0.993)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703708|protein_coding|10/15||ENST00000703708.1:c.353A>G|ENSP00000515442.1:p.Asp118Gly|990|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515442||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703709|protein_coding|8/13||ENST00000703709.1:c.353A>G|ENSP00000515443.1:p.Asp118Gly|574|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515443||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703710|protein_coding|9/14||ENST00000703710.1:c.353A>G|ENSP00000515444.1:p.Asp118Gly|902|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515444||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|CDD:cd00200&Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&SMART:SM00320&Superfamily:SSF50978&PANTHER:PTHR19850&Prints:PR00319|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1||,C|missense_variant|MODERATE|GNB1|ENSG00000078369|Transcript|ENST00000703711|protein_coding|10/15||ENST00000703711.1:c.353A>G|ENSP00000515445.1:p.Asp118Gly|883|353|118|D/G|gAt/gGt|rs1553194162&CM1612300|1||-1||SNV|HGNC|HGNC:4396|||||P1|CCDS34.1|ENSP00000515445||A0A140VJJ8.16|UPI00000230B3||1|deleterious_low_confidence(0)|probably_damaging(0.982)|Gene3D:2.130.10.10&Pfam:PF00400&PIRSF:PIRSF002394&Prints:PR00319&PANTHER:PTHR19850&SMART:SM00320&Superfamily:SSF50978&CDD:cd00200|||||||||||||||||||||||||||||||not_provided&pathogenic||1&1||||||||||||||32|4.523403|P&P&P&P&P|0.99219|0.9996&0.9758&0.9995&0.9949&0.9981|ENST00000610897&ENST00000615252&ENST00000378609&ENST00000439272&ENST00000434686|D|D&D&D|D&.&D&.&.|D&.&D&.&.|D|0.93616|0.877460956573|.&.&D&D&D|P62873&B3KVK2&P62873&F6X3N5&F6UT28|YES&.&.&.&.|10819326&25485910&27108799&27668284&28087732|0.70&0.70&0.70&0.70&0.70|Inborn_genetic_diseases|||||||39|-31|1|-49|0.00|0.00|0.01|0.02|GNB1|| bcftools-1.21/test/split-vep.types.1.out000066400000000000000000000000711467060157400202150ustar00rootroot000000000000008586-8599/9231,.,. 8523-8536/8835,.,. 2841-2846/2944,.,. bcftools-1.21/test/split-vep.types.2.out000066400000000000000000000000331467060157400202140ustar00rootroot000000000000008586,.,. 8523,.,. 2841,.,. bcftools-1.21/test/split-vep.types.vcf000066400000000000000000000051731467060157400200350ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 48565192 . GGTACCCGCTCTGCAGGTAGGGCAGGGTGTGCTGGGAGCAGTGGCTGCTGGCCCCGGGGCAAGGTGGGCAGCACTGATTTCCACTGTGTGCACACAGTGCCCATGCGTGTGCCCTGCATGCAGACCCTACGTGCTTGGCGTGTGCCCTGCATTCATGGACACCCATGTGCGTGTCTCGGCCCCACCCATAGCTGCCCCACGGGTTCAGCTGTCCTCACCTTCC G . PASS CSQ=-|splice_acceptor_variant&splice_donor_variant&frameshift_variant&stop_lost&splice_donor_5th_base_variant&intron_variant|HIGH|COL7A1|1294|Transcript|NM_000094.4|protein_coding|116-117/119|116/118|NM_000094.4:c.8523_8536del|NP_000085.1:p.Glu2841AspfsTer3|8586-8599/9231|8523-8536/8835|2841-2846/2944|EEGEDS*TRGAAMGGAETRTWVSMNAGHTPST*GLHAGHTHGHCVHTVEISAAHLAPGPAATAPSTPCPTCRAGTX/DX|gaGGAAGGTGAGGACAGCTGAACCCGTGGGGCAGCTATGGGTGGGGCCGAGACACGCACATGGGTGTCCATGAATGCAGGGCACACGCCAAGCACGTAGGGTCTGCATGCAGGGCACACGCATGGGCACTGTGTGCACACAGTGGAAATCAGTGCTGCCCACCTTGCCCCGGGGCCAGCAGCCACTGCTCCCAGCACACCCTGCCCTACCTGCAGAGCGGGTACcc/gacc||1||-1||1|EntrezGene||||||||||||||||||||||||||||VUS|0.5681088|||||||AD&AR||||||||||||||4|1A_(cf_Gene_count%2C_RE_gene%2C_+0.00)%3B2E-1_(COL7A1%2C_+0.90)%3B3A_(1_gene%2C_+0.00)%3B5F_(+0.00)|0.9||99.7739|,-|upstream_gene_variant|MODIFIER|PFKFB4|5210|Transcript|NM_001317136.2|protein_coding|||||||||||1|4064|-1|||EntrezGene||||||||||||||||||||||||||||VUS|0.5681742|||||||||||||||||||||||||99.7739|,-|upstream_gene_variant|MODIFIER|UCN2|90226|Transcript|NM_033199.4|protein_coding|||||||||||1|1412|-1|||EntrezGene||||||||||||||||||||||||||||VUS|0.5681742|||||||||||||||||||||||||99.7739| bcftools-1.21/test/split-vep.vcf000066400000000000000000023227471467060157400167050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 14464 . A T 2235.88 PASS AF=1;CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1568T>A||1568|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1682T>A||1682|||||rs546169444|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs546169444|1|55|1||SNV|HGNC|37102|YES|||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|11/11||ENST00000488147.1:n.1291T>A||1291|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|13/13||ENST00000538476.1:n.1530T>A||1530|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1315T>A||1315|||||rs546169444|1||-1||SNV|HGNC|38034||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000002|open_chromatin_region||||||||||rs546169444|1||||SNV||||||||||||||||||0.0958|0.0144|0.1138|0.005|0.1859|0.1943||||||||||||0.1943|SAS||||||||||||||||||||||||| 1 14469 . C T 37.38 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1563G>A||1563||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1677G>A||1677||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|60|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|11/11||ENST00000488147.1:n.1286G>A||1286||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|13/13||ENST00000538476.1:n.1525G>A||1525||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1310G>A||1310||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000002|open_chromatin_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14522 . G A 627.64 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1510C>T||1510||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1624C>T||1624||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|113|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-21C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-20C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1257C>T||1257||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14542 . A G 1090.23 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1490T>C||1490|||||rs1045833|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1604T>C||1604|||||rs1045833|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs1045833|1|133|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-41T>C|||||||rs1045833|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-40T>C|||||||rs1045833|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1237T>C||1237|||||rs1045833|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14574 . A G 278.74 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1458T>C||1458|||||rs28503599|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1572T>C||1572|||||rs28503599|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs28503599|1|165|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-73T>C|||||||rs28503599|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-72T>C|||||||rs28503599|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1205T>C||1205|||||rs28503599|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14590 . G A 82.97 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1442C>T||1442|||||rs707679|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1556C>T||1556|||||rs707679|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs707679|1|181|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-89C>T|||||||rs707679|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-88C>T|||||||rs707679|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1189C>T||1189|||||rs707679|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14599 . T A 66.88 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1433A>T||1433|||||rs707680|1||-1||SNV|HGNC|38034|||||||||||||||||0.121|0.1758|0.0893|0.161|0.2096||||||||||||0.2096|SAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1547A>T||1547|||||rs707680|1||-1||SNV|HGNC|38034|YES||||||||||||||||0.121|0.1758|0.0893|0.161|0.2096||||||||||||0.2096|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs707680|1|190|1||SNV|HGNC|37102|YES||||||||||||||||0.121|0.1758|0.0893|0.161|0.2096||||||||||||0.2096|SAS|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-98A>T|||||||rs707680|1||-1||SNV|HGNC|38034|||||||||||||||||0.121|0.1758|0.0893|0.161|0.2096||||||||||||0.2096|SAS|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-97A>T|||||||rs707680|1||-1||SNV|HGNC|38034|||||||||||||||||0.121|0.1758|0.0893|0.161|0.2096||||||||||||0.2096|SAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1180A>T||1180|||||rs707680|1||-1||SNV|HGNC|38034|||||||||||||||||0.121|0.1758|0.0893|0.161|0.2096||||||||||||0.2096|SAS||||||||||||||||||||||||| 1 14653 . C T 115085 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1379G>A||1379|||||rs62635297|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1493G>A||1493|||||rs62635297|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs62635297|1|244|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-152G>A|||||||rs62635297|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-151G>A|||||||rs62635297|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1126G>A||1126|||||rs62635297|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14671 . G C 103578 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1361C>G||1361|||||rs201055865|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1475C>G||1475|||||rs201055865|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201055865|1|262|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-170C>G|||||||rs201055865|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-169C>G|||||||rs201055865|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1108C>G||1108|||||rs201055865|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14673 . G C 578.09 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1359C>G||1359|||||rs4690|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1473C>G||1473|||||rs4690|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs4690|1|264|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-172C>G|||||||rs4690|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-171C>G|||||||rs4690|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1106C>G||1106|||||rs4690|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14677 . G A 629.9 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1355C>T||1355|||||rs201327123|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1469C>T||1469|||||rs201327123|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201327123|1|268|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-176C>T|||||||rs201327123|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-175C>T|||||||rs201327123|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1102C>T||1102|||||rs201327123|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14696 . C A 15418.3 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1336G>T||1336||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1450G>T||1450||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|287|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-195G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-194G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1083G>T||1083||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14699 . C G 167.97 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1333G>C||1333||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1447G>C||1447||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|290|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-198G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-197G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1080G>C||1080||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14729 . C A 55.81 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1303G>T||1303||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1417G>T||1417||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|320|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-228G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-227G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1050G>T||1050||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14747 . C G 10873.1 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1285G>C||1285||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1399G>C||1399||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|338|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1254-246G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1492-245G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1032G>C||1032||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14763 . G C 266.95 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1269C>G||1269||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1383C>G||1383||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|354|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+242C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+237C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1016C>G||1016||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14773 . C T 211.29 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1259G>A||1259|||||rs878915777|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1373G>A||1373|||||rs878915777|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs878915777|1|364|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+232G>A|||||||rs878915777|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+227G>A|||||||rs878915777|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.1006G>A||1006|||||rs878915777|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14815 . C T 171.74 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|10/10||ENST00000423562.1:n.1217G>A||1217||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|12/12||ENST00000438504.2:n.1331G>A||1331||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|406|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+190G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+185G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|9/9||ENST00000541675.1:n.964G>A||964||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14842 . G T 122.69 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1203-13C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1317-13C>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|433|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+163C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+158C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.950-13C>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14843 . G A 75.68 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1203-14C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1317-14C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|434|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+162C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+157C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.950-14C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14860 . G T 163.73 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1203-31C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1317-31C>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|451|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+145C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+140C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.950-31C>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14863 . G T 72.04 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1203-34C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1317-34C>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|454|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+142C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+137C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.950-34C>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14891 . A C 264.99 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1203-62T>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1317-62T>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|482|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+114T>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+109T>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.950-62T>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14896 . T C 381.43 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1203-67A>G|||||||rs779143624|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1317-67A>G|||||||rs779143624|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs779143624|1|487|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+109A>G|||||||rs779143624|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+104A>G|||||||rs779143624|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.950-67A>G|||||||rs779143624|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14907 . A G 5.23508e+06 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+63T>C|||||||rs6682375|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+63T>C|||||||rs6682375|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs6682375|1|498|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+98T>C|||||||rs6682375|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+93T>C|||||||rs6682375|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+63T>C|||||||rs6682375|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14908 . G C 11632.7 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+62C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+62C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|499|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+97C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+92C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+62C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14929 . C T 144.69 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+41G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+41G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|520|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+76G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+71G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+41G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14930 . A G 9.17751e+06 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+40T>C|||||||rs6682385|1||-1||SNV|HGNC|38034||||||||||||||||0.4822|0.4811|0.5231|0.4137|0.5209|0.4857||||||||||||0.5231|AMR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+40T>C|||||||rs6682385|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.4822|0.4811|0.5231|0.4137|0.5209|0.4857||||||||||||0.5231|AMR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs6682385|1|521|1||SNV|HGNC|37102|YES|||||||||||||||0.4822|0.4811|0.5231|0.4137|0.5209|0.4857||||||||||||0.5231|AMR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+75T>C|||||||rs6682385|1||-1||SNV|HGNC|38034||||||||||||||||0.4822|0.4811|0.5231|0.4137|0.5209|0.4857||||||||||||0.5231|AMR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+70T>C|||||||rs6682385|1||-1||SNV|HGNC|38034||||||||||||||||0.4822|0.4811|0.5231|0.4137|0.5209|0.4857||||||||||||0.5231|AMR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+40T>C|||||||rs6682385|1||-1||SNV|HGNC|38034||||||||||||||||0.4822|0.4811|0.5231|0.4137|0.5209|0.4857||||||||||||0.5231|AMR||||||||||||||||||||||||| 1 14931 . A G 318.28 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+39T>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+39T>C||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|522|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+74T>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+69T>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+39T>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14933 . G A 823196 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+37C>T|||||||rs199856693|1||-1||SNV|HGNC|38034||||||||||||||||0.0284|0.0015|0.0375|0.0268|0.0507|0.0368||||||||||||0.0507|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+37C>T|||||||rs199856693|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0284|0.0015|0.0375|0.0268|0.0507|0.0368||||||||||||0.0507|EUR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs199856693|1|524|1||SNV|HGNC|37102|YES|||||||||||||||0.0284|0.0015|0.0375|0.0268|0.0507|0.0368||||||||||||0.0507|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+72C>T|||||||rs199856693|1||-1||SNV|HGNC|38034||||||||||||||||0.0284|0.0015|0.0375|0.0268|0.0507|0.0368||||||||||||0.0507|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+67C>T|||||||rs199856693|1||-1||SNV|HGNC|38034||||||||||||||||0.0284|0.0015|0.0375|0.0268|0.0507|0.0368||||||||||||0.0507|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+37C>T|||||||rs199856693|1||-1||SNV|HGNC|38034||||||||||||||||0.0284|0.0015|0.0375|0.0268|0.0507|0.0368||||||||||||0.0507|EUR||||||||||||||||||||||||| 1 14935 . G T 293.95 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+35C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+35C>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|526|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+70C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+65C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+35C>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14936 . C T 359.37 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+34G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+34G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|527|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+69G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+64G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+34G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14938 . G T 605.66 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+32C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+32C>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|529|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+67C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+62C>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+32C>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14947 . C T 4582.44 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+23G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+23G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|538|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+58G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+53G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+23G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14948 . G A 238796 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+22C>T|||||||rs201855936|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+22C>T|||||||rs201855936|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201855936|1|539|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+57C>T|||||||rs201855936|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+52C>T|||||||rs201855936|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+22C>T|||||||rs201855936|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14949 . G C 4632.04 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+21C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+21C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|540|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+56C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+51C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+21C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14955 . G A 3174.52 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+15C>T|||||||rs878871318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+15C>T|||||||rs878871318|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs878871318|1|546|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+50C>T|||||||rs878871318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+45C>T|||||||rs878871318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+15C>T|||||||rs878871318|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14956 . G A 99.93 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+14C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+14C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|547|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+49C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+44C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+14C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14959 . C G 169.87 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+11G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+11G>C||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|550|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+46G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+41G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+11G>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14961 . G A 13090.5 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||9/9|ENST00000423562.1:n.1202+9C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||11/11|ENST00000438504.2:n.1316+9C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|552|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+44C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+39C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||8/8|ENST00000541675.1:n.949+9C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14971 . C T 325.83 PASS CSQ=T|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1201G>A||1201||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1315G>A||1315||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|562|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+34G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+29G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.948G>A||948||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14974 . G C 25977.9 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1198C>G||1198||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1312C>G||1312||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|565|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+31C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+26C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.945C>G||945||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14976 . G A,C 619845 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1196C>T||1196|||||rs71252251|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1196C>G||1196||||||2||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1310C>T||1310|||||rs71252251|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1310C>G||1310||||||2||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs71252251|1|567|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||2|567|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+29C>T|||||||rs71252251|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+29C>G||||||||2||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+24C>T|||||||rs71252251|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+24C>G||||||||2||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.943C>T||943|||||rs71252251|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.943C>G||943||||||2||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 14978 . C T 1245.9 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1194G>A||1194||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1308G>A||1308||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|569|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+27G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||12/12|ENST00000538476.1:n.1491+22G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.941G>A||941||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15004 . C T 22206.8 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1168G>A||1168||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1282G>A||1282||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|595|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_donor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||10/10|ENST00000488147.1:n.1253+1G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|12/13||ENST00000538476.1:n.1487G>A||1487||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.915G>A||915||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15029 . G A 8345.91 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1143C>T||1143|||||rs201045431|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1257C>T||1257|||||rs201045431|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201045431|1|620|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|10/11||ENST00000488147.1:n.1229C>T||1229|||||rs201045431|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|12/13||ENST00000538476.1:n.1462C>T||1462|||||rs201045431|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.890C>T||890|||||rs201045431|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15038 . A C 137.03 PASS CSQ=C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|9/10||ENST00000423562.1:n.1134T>G||1134|||||rs879195309|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|11/12||ENST00000438504.2:n.1248T>G||1248|||||rs879195309|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs879195309|1|629|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|10/11||ENST00000488147.1:n.1220T>G||1220|||||rs879195309|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|12/13||ENST00000538476.1:n.1453T>G||1453|||||rs879195309|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|8/9||ENST00000541675.1:n.881T>G||881|||||rs879195309|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15058 . G C 141.59 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1134-20C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1248-20C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|649|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1220-20C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1453-20C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-20C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15065 . G A 68.6 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1134-27C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1248-27C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|656|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1220-27C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1453-27C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-27C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15072 . G C 64.24 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1134-34C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1248-34C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|663|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1220-34C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1453-34C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-34C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15086 . G A 68.29 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1134-48C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1248-48C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|677|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1220-48C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1453-48C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-48C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15112 . C T 345.36 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1134-74G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1248-74G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|703|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1220-74G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1453-74G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-74G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15118 . A G 263658 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1134-80T>C|||||||rs11580262|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1248-80T>C|||||||rs11580262|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs11580262|1|709|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1220-80T>C|||||||rs11580262|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1453-80T>C|||||||rs11580262|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-80T>C|||||||rs11580262|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15688 . C T 243.24 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1133+108G>A|||||||rs879651396|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1247+108G>A|||||||rs879651396|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs879651396|1|1279|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1219+108G>A|||||||rs879651396|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1452+108G>A|||||||rs879651396|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-650G>A|||||||rs879651396|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000003|TF_binding_site||||||||||rs879651396|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15759 . C T 49.67 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1133+37G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1247+37G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1350|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1219+37G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1452+37G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-721G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000003|TF_binding_site|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15773 . T C 91.41 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1133+23A>G|||||||rs2691318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1247+23A>G|||||||rs2691318|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs2691318|1|1364|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1219+23A>G|||||||rs2691318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1452+23A>G|||||||rs2691318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-735A>G|||||||rs2691318|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000003|TF_binding_site||||||||||rs2691318|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15776 . A T 37.57 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1133+20T>A|||||||rs548251696|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1247+20T>A|||||||rs548251696|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs548251696|1|1367|1||SNV|HGNC|37102|YES|||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1219+20T>A|||||||rs548251696|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1452+20T>A|||||||rs548251696|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-738T>A|||||||rs548251696|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000003|TF_binding_site||||||||||rs548251696|1||||SNV||||||||||||||||||0.0004|0.0015|0|0|0|0||||||||||||0.0015|AFR||||||||||||||||||||||||| 1 15777 . A G 129.16 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1133+19T>C|||||||rs2691317|1||-1||SNV|HGNC|38034|||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1247+19T>C|||||||rs2691317|1||-1||SNV|HGNC|38034|YES||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs2691317|1|1368|1||SNV|HGNC|37102|YES||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1219+19T>C|||||||rs2691317|1||-1||SNV|HGNC|38034|||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1452+19T>C|||||||rs2691317|1||-1||SNV|HGNC|38034|||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-739T>C|||||||rs2691317|1||-1||SNV|HGNC|38034|||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS|||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000003|TF_binding_site||||||||||rs2691317|1||||SNV|||||||||||||||||||0.0159|0.0086|0.0744|0.0149|0.0256||||||||||||0.0744|EAS||||||||||||||||||||||||| 1 15787 . C T 65.03 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||8/9|ENST00000423562.1:n.1133+9G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||10/11|ENST00000438504.2:n.1247+9G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1378|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||9/10|ENST00000488147.1:n.1219+9G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||11/12|ENST00000538476.1:n.1452+9G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-749G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15811 . T G 123924 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1118A>C||1118||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|10/12||ENST00000438504.2:n.1232A>C||1232||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1402|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1204A>C||1204||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|11/13||ENST00000538476.1:n.1437A>C||1437||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-773A>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15817 . G T 220.51 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1112C>A||1112|||||rs2691316|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|10/12||ENST00000438504.2:n.1226C>A||1226|||||rs2691316|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs2691316|1|1408|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1198C>A||1198|||||rs2691316|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|11/13||ENST00000538476.1:n.1431C>A||1431|||||rs2691316|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-779C>A|||||||rs2691316|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15820 . G T 130982 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1109C>A||1109|||||rs2691315|1||-1||SNV|HGNC|38034||||||||||||||||0.4105|0.4849|0.2939|0.6052|0.2714|0.3354||||||||||||0.6052|EAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|10/12||ENST00000438504.2:n.1223C>A||1223|||||rs2691315|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.4105|0.4849|0.2939|0.6052|0.2714|0.3354||||||||||||0.6052|EAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs2691315|1|1411|1||SNV|HGNC|37102|YES|||||||||||||||0.4105|0.4849|0.2939|0.6052|0.2714|0.3354||||||||||||0.6052|EAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1195C>A||1195|||||rs2691315|1||-1||SNV|HGNC|38034||||||||||||||||0.4105|0.4849|0.2939|0.6052|0.2714|0.3354||||||||||||0.6052|EAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|11/13||ENST00000538476.1:n.1428C>A||1428|||||rs2691315|1||-1||SNV|HGNC|38034||||||||||||||||0.4105|0.4849|0.2939|0.6052|0.2714|0.3354||||||||||||0.6052|EAS|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-782C>A|||||||rs2691315|1||-1||SNV|HGNC|38034||||||||||||||||0.4105|0.4849|0.2939|0.6052|0.2714|0.3354||||||||||||0.6052|EAS||||||||||||||||||||||||| 1 15903 . G C,GC 130635 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1026C>G||1026||||||1||-1||indel|HGNC|38034||||||||||||||||0.4411|||||||||||||||||||||||||||||||||||||||||||,GC|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1025_1026insG||1026|||||rs557514207|2||-1||indel|HGNC|38034||||||||||||||||0.4411|0.0431|0.415|0.8681|0.4652|0.5327||||||||||||0.8681|EAS|||||||||||||||||||||||||,C|non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||9/11|ENST00000438504.2:n.1141+1C>G||||||||1||-1||indel|HGNC|38034|YES|||||||||||||||0.4411|||||||||||||||||||||||||||||||||||||||||||,GC|non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||9/11|ENST00000438504.2:n.1141_1141+1insG|||||||rs557514207|2||-1||indel|HGNC|38034|YES|||||||||||||||0.4411|0.0431|0.415|0.8681|0.4652|0.5327||||||||||||0.8681|EAS|||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1494|1||indel|HGNC|37102|YES|||||||||||||||0.4411|||||||||||||||||||||||||||||||||||||||||||,GC|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs557514207|2|1494|1||indel|HGNC|37102|YES|||||||||||||||0.4411|0.0431|0.415|0.8681|0.4652|0.5327||||||||||||0.8681|EAS|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1112C>G||1112||||||1||-1||indel|HGNC|38034||||||||||||||||0.4411|||||||||||||||||||||||||||||||||||||||||||,GC|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1111_1112insG||1112|||||rs557514207|2||-1||indel|HGNC|38034||||||||||||||||0.4411|0.0431|0.415|0.8681|0.4652|0.5327||||||||||||0.8681|EAS|||||||||||||||||||||||||,C|non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||10/12|ENST00000538476.1:n.1346+1C>G||||||||1||-1||indel|HGNC|38034||||||||||||||||0.4411|||||||||||||||||||||||||||||||||||||||||||,GC|non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||10/12|ENST00000538476.1:n.1346_1346+1insG|||||||rs557514207|2||-1||indel|HGNC|38034||||||||||||||||0.4411|0.0431|0.415|0.8681|0.4652|0.5327||||||||||||0.8681|EAS|||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-865C>G||||||||1||-1||indel|HGNC|38034||||||||||||||||0.4411|||||||||||||||||||||||||||||||||||||||||||,GC|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-866_881-865insG|||||||rs557514207|2||-1||indel|HGNC|38034||||||||||||||||0.4411|0.0431|0.415|0.8681|0.4652|0.5327||||||||||||0.8681|EAS||||||||||||||||||||||||| 1 15906 . A C 42.6 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1023T>G||1023||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|9/12||ENST00000438504.2:n.1139T>G||1139||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1497|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1109T>G||1109||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|10/13||ENST00000538476.1:n.1344T>G||1344||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-868T>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15908 . C G 42.05 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1021G>C||1021||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|9/12||ENST00000438504.2:n.1137G>C||1137||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1499|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1107G>C||1107||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|10/13||ENST00000538476.1:n.1342G>C||1342||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-870G>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15912 . C T 162.1 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1017G>A||1017|||||rs17855870|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|9/12||ENST00000438504.2:n.1133G>A||1133|||||rs17855870|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs17855870|1|1503|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1103G>A||1103|||||rs17855870|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|10/13||ENST00000538476.1:n.1338G>A||1338|||||rs17855870|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-874G>A|||||||rs17855870|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15922 . A G 619.18 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|8/10||ENST00000423562.1:n.1007T>C||1007||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|9/12||ENST00000438504.2:n.1123T>C||1123||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1513|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|9/11||ENST00000488147.1:n.1093T>C||1093||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|10/13||ENST00000538476.1:n.1328T>C||1328||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.881-884T>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15974 . C G 55535.6 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.982-27G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1098-27G>C||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1565|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1068-27G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1303-27G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+880G>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 15989 . G C 89.14 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.982-42C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1098-42C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|1580|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1068-42C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1303-42C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+865C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16014 . C T 116.59 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.982-67G>A|||||||rs75082847|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1098-67G>A|||||||rs75082847|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs75082847|1|1605|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1068-67G>A|||||||rs75082847|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1303-67G>A|||||||rs75082847|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+840G>A|||||||rs75082847|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16495 . G C 18764.9 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.981+112C>G|||||||rs3210724|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1097+112C>G|||||||rs3210724|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs3210724|1|2086|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1067+112C>G|||||||rs3210724|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1302+112C>G|||||||rs3210724|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+359C>G|||||||rs3210724|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16497 . A G 14740.9 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.981+110T>C|||||||rs150723783|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1097+110T>C|||||||rs150723783|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs150723783|1|2088|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1067+110T>C|||||||rs150723783|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1302+110T>C|||||||rs150723783|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+357T>C|||||||rs150723783|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16534 . C T 15297.4 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.981+73G>A|||||||rs15642|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1097+73G>A|||||||rs15642|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs15642|1|2125|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1067+73G>A|||||||rs15642|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1302+73G>A|||||||rs15642|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+320G>A|||||||rs15642|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16571 . G A 14141.6 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||7/9|ENST00000423562.1:n.981+36C>T|||||||rs12405900|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||8/11|ENST00000438504.2:n.1097+36C>T|||||||rs12405900|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs12405900|1|2162|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||8/10|ENST00000488147.1:n.1067+36C>T|||||||rs12405900|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||9/12|ENST00000538476.1:n.1302+36C>T|||||||rs12405900|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+283C>T|||||||rs12405900|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16580 . 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G A 246.21 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|7/10||ENST00000423562.1:n.906C>T||906|||||rs12405913|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|8/12||ENST00000438504.2:n.1022C>T||1022|||||rs12405913|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs12405913|1|2273|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|8/11||ENST00000488147.1:n.992C>T||992|||||rs12405913|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|9/13||ENST00000538476.1:n.1227C>T||1227|||||rs12405913|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+172C>T|||||||rs12405913|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16719 . T A 157.98 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|7/10||ENST00000423562.1:n.869A>T||869|||||rs62636367|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|8/12||ENST00000438504.2:n.985A>T||985|||||rs62636367|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs62636367|1|2310|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|8/11||ENST00000488147.1:n.955A>T||955|||||rs62636367|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|9/13||ENST00000538476.1:n.1190A>T||1190|||||rs62636367|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+135A>T|||||||rs62636367|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16792 . G A 35673.5 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||6/9|ENST00000423562.1:n.823-27C>T|||||||rs201330479|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||7/11|ENST00000438504.2:n.939-27C>T|||||||rs201330479|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201330479|1|2383|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||7/10|ENST00000488147.1:n.909-27C>T|||||||rs201330479|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||7/12|ENST00000538476.1:n.1146-27C>T|||||||rs201330479|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+62C>T|||||||rs201330479|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16825 . C A 35.83 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||6/9|ENST00000423562.1:n.822+33G>T|||||||rs774196730|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||7/11|ENST00000438504.2:n.938+29G>T|||||||rs774196730|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs774196730|1|2416|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||7/10|ENST00000488147.1:n.908+33G>T|||||||rs774196730|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||7/12|ENST00000538476.1:n.1145+33G>T|||||||rs774196730|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+29G>T|||||||rs774196730|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16841 . G T 2703.35 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||6/9|ENST00000423562.1:n.822+17C>A|||||||rs62636368|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||7/11|ENST00000438504.2:n.938+13C>A|||||||rs62636368|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs62636368|1|2432|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||7/10|ENST00000488147.1:n.908+17C>A|||||||rs62636368|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||7/12|ENST00000538476.1:n.1145+17C>A|||||||rs62636368|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||7/8|ENST00000541675.1:n.880+13C>A|||||||rs62636368|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16856 . A G 55.46 PASS CSQ=G|splice_donor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||6/9|ENST00000423562.1:n.822+2T>C|||||||rs3891260|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|7/12||ENST00000438504.2:n.936T>C||936|||||rs3891260|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs3891260|1|2447|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_donor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||7/10|ENST00000488147.1:n.908+2T>C|||||||rs3891260|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_donor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||7/12|ENST00000538476.1:n.1145+2T>C|||||||rs3891260|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|7/9||ENST00000541675.1:n.878T>C||878|||||rs3891260|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16957 . G T 97.38 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|6/10||ENST00000423562.1:n.723C>A||723|||||rs200658479|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|7/12||ENST00000438504.2:n.835C>A||835|||||rs200658479|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs200658479|1|2548|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|7/11||ENST00000488147.1:n.809C>A||809|||||rs200658479|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|7/13||ENST00000538476.1:n.1046C>A||1046|||||rs200658479|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|7/9||ENST00000541675.1:n.777C>A||777|||||rs200658479|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 16977 . G A 286.44 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|6/10||ENST00000423562.1:n.703C>T||703|||||rs879121945|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|7/12||ENST00000438504.2:n.815C>T||815|||||rs879121945|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs879121945|1|2568|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|7/11||ENST00000488147.1:n.789C>T||789|||||rs879121945|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|7/13||ENST00000538476.1:n.1026C>T||1026|||||rs879121945|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|7/9||ENST00000541675.1:n.757C>T||757|||||rs879121945|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17020 . G A 114.11 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|6/10||ENST00000423562.1:n.660C>T||660|||||rs199740902|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|7/12||ENST00000438504.2:n.772C>T||772|||||rs199740902|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs199740902|1|2611|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|7/11||ENST00000488147.1:n.746C>T||746|||||rs199740902|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|7/13||ENST00000538476.1:n.983C>T||983|||||rs199740902|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|7/9||ENST00000541675.1:n.714C>T||714|||||rs199740902|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17222 . A G 1136.07 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||5/9|ENST00000423562.1:n.624+11T>C|||||||rs200978805|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||6/11|ENST00000438504.2:n.736+11T>C|||||||rs200978805|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs200978805|1|2813|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||6/10|ENST00000488147.1:n.710+11T>C|||||||rs200978805|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||6/12|ENST00000538476.1:n.947+11T>C|||||||rs200978805|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||6/8|ENST00000541675.1:n.678+11T>C|||||||rs200978805|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17289 . CCT C 51987.1 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|5/10||ENST00000423562.1:n.566_567del||566-567||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|6/12||ENST00000438504.2:n.678_679del||678-679||||||1||-1||deletion|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|2881|1||deletion|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|6/11||ENST00000488147.1:n.652_653del||652-653||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|6/13||ENST00000538476.1:n.889_890del||889-890||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|6/9||ENST00000541675.1:n.620_621del||620-621||||||1||-1||deletion|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17358 . ACTT A 5316.19 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|5/10||ENST00000423562.1:n.496_498del||496-498|||||rs749387668|1||-1||deletion|HGNC|38034||||||||||||||||||||||||0.001247|0.001202|0.0009235|0.001387|0|0.000269|0.001388|0.0005807|0.004833|0.004833|gnomAD_SAS|||||||||||||||rs749387668|6.83357e-03|4.81888e-03|1.14566e-03|9.20980e-04|5.78704e-04|0.00000e+00|2.65534e-04|1.27543e-03|9.16590e-04|4.81888e-03,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|6/12||ENST00000438504.2:n.608_610del||608-610|||||rs749387668|1||-1||deletion|HGNC|38034|YES|||||||||||||||||||||||0.001247|0.001202|0.0009235|0.001387|0|0.000269|0.001388|0.0005807|0.004833|0.004833|gnomAD_SAS|||||||||||||||rs749387668|6.83357e-03|4.81888e-03|1.14566e-03|9.20980e-04|5.78704e-04|0.00000e+00|2.65534e-04|1.27543e-03|9.16590e-04|4.81888e-03,-|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs749387668|1|2950|1||deletion|HGNC|37102|YES|||||||||||||||||||||||0.001247|0.001202|0.0009235|0.001387|0|0.000269|0.001388|0.0005807|0.004833|0.004833|gnomAD_SAS|||||||||||||||rs749387668|6.83357e-03|4.81888e-03|1.14566e-03|9.20980e-04|5.78704e-04|0.00000e+00|2.65534e-04|1.27543e-03|9.16590e-04|4.81888e-03,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|6/11||ENST00000488147.1:n.582_584del||582-584|||||rs749387668|1||-1||deletion|HGNC|38034||||||||||||||||||||||||0.001247|0.001202|0.0009235|0.001387|0|0.000269|0.001388|0.0005807|0.004833|0.004833|gnomAD_SAS|||||||||||||||rs749387668|6.83357e-03|4.81888e-03|1.14566e-03|9.20980e-04|5.78704e-04|0.00000e+00|2.65534e-04|1.27543e-03|9.16590e-04|4.81888e-03,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|6/13||ENST00000538476.1:n.819_821del||819-821|||||rs749387668|1||-1||deletion|HGNC|38034||||||||||||||||||||||||0.001247|0.001202|0.0009235|0.001387|0|0.000269|0.001388|0.0005807|0.004833|0.004833|gnomAD_SAS|||||||||||||||rs749387668|6.83357e-03|4.81888e-03|1.14566e-03|9.20980e-04|5.78704e-04|0.00000e+00|2.65534e-04|1.27543e-03|9.16590e-04|4.81888e-03,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|6/9||ENST00000541675.1:n.550_552del||550-552|||||rs749387668|1||-1||deletion|HGNC|38034||||||||||||||||||||||||0.001247|0.001202|0.0009235|0.001387|0|0.000269|0.001388|0.0005807|0.004833|0.004833|gnomAD_SAS|||||||||||||||rs749387668|6.83357e-03|4.81888e-03|1.14566e-03|9.20980e-04|5.78704e-04|0.00000e+00|2.65534e-04|1.27543e-03|9.16590e-04|4.81888e-03 1 17365 . C G 120842 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|5/10||ENST00000423562.1:n.492G>C||492||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs369606208|1.87059e-01|3.17990e-01|6.13226e-02|1.84096e-01|1.27148e-01|3.17990e-01|1.63348e-01|1.44187e-01|1.71171e-01|1.84247e-01,G|splice_acceptor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-1G>C||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||rs369606208|1.87059e-01|3.17990e-01|6.13226e-02|1.84096e-01|1.27148e-01|3.17990e-01|1.63348e-01|1.44187e-01|1.71171e-01|1.84247e-01,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|2956|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||rs369606208|1.87059e-01|3.17990e-01|6.13226e-02|1.84096e-01|1.27148e-01|3.17990e-01|1.63348e-01|1.44187e-01|1.71171e-01|1.84247e-01,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|6/11||ENST00000488147.1:n.578G>C||578||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs369606208|1.87059e-01|3.17990e-01|6.13226e-02|1.84096e-01|1.27148e-01|3.17990e-01|1.63348e-01|1.44187e-01|1.71171e-01|1.84247e-01,G|splice_acceptor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-1G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs369606208|1.87059e-01|3.17990e-01|6.13226e-02|1.84096e-01|1.27148e-01|3.17990e-01|1.63348e-01|1.44187e-01|1.71171e-01|1.84247e-01,G|splice_acceptor_variant&non_coding_transcript_variant|HIGH|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-1G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs369606208|1.87059e-01|3.17990e-01|6.13226e-02|1.84096e-01|1.27148e-01|3.17990e-01|1.63348e-01|1.44187e-01|1.71171e-01|1.84247e-01 1 17373 . A G 15412.8 PASS CSQ=G|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-5T>C|||||||rs750111615|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.006692|0.008798|0.007612|0.005935|0.002877|0.007561|0.007138|0.01005|0.00407|0.01005|gnomAD_OTH|||||||||||||||rs750111615|3.02360e-02|8.02792e-03|8.02792e-03|7.59968e-03|5.54871e-03|3.09406e-03|7.65504e-03|6.93711e-03|8.85827e-03|4.38739e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-9T>C|||||||rs750111615|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.006692|0.008798|0.007612|0.005935|0.002877|0.007561|0.007138|0.01005|0.00407|0.01005|gnomAD_OTH|||||||||||||||rs750111615|3.02360e-02|8.02792e-03|8.02792e-03|7.59968e-03|5.54871e-03|3.09406e-03|7.65504e-03|6.93711e-03|8.85827e-03|4.38739e-03,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs750111615|1|2964|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.006692|0.008798|0.007612|0.005935|0.002877|0.007561|0.007138|0.01005|0.00407|0.01005|gnomAD_OTH|||||||||||||||rs750111615|3.02360e-02|8.02792e-03|8.02792e-03|7.59968e-03|5.54871e-03|3.09406e-03|7.65504e-03|6.93711e-03|8.85827e-03|4.38739e-03,G|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-5T>C|||||||rs750111615|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.006692|0.008798|0.007612|0.005935|0.002877|0.007561|0.007138|0.01005|0.00407|0.01005|gnomAD_OTH|||||||||||||||rs750111615|3.02360e-02|8.02792e-03|8.02792e-03|7.59968e-03|5.54871e-03|3.09406e-03|7.65504e-03|6.93711e-03|8.85827e-03|4.38739e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-9T>C|||||||rs750111615|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.006692|0.008798|0.007612|0.005935|0.002877|0.007561|0.007138|0.01005|0.00407|0.01005|gnomAD_OTH|||||||||||||||rs750111615|3.02360e-02|8.02792e-03|8.02792e-03|7.59968e-03|5.54871e-03|3.09406e-03|7.65504e-03|6.93711e-03|8.85827e-03|4.38739e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-9T>C|||||||rs750111615|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.006692|0.008798|0.007612|0.005935|0.002877|0.007561|0.007138|0.01005|0.00407|0.01005|gnomAD_OTH|||||||||||||||rs750111615|3.02360e-02|8.02792e-03|8.02792e-03|7.59968e-03|5.54871e-03|3.09406e-03|7.65504e-03|6.93711e-03|8.85827e-03|4.38739e-03 1 17375 . A G 25487.2 PASS CSQ=G|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-7T>C|||||||rs755771866|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02589|0.02678|0.0622|0.01097|0.02773|0.0171|0.01874|0.021|0.0167|0.0622|gnomAD_AMR|||||||||||||||rs755771866|6.55644e-02|6.10034e-02|2.64117e-02|6.10034e-02|1.10104e-02|2.79881e-02|1.72733e-02|1.85768e-02|2.08117e-02|1.68539e-02,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-11T>C|||||||rs755771866|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.02589|0.02678|0.0622|0.01097|0.02773|0.0171|0.01874|0.021|0.0167|0.0622|gnomAD_AMR|||||||||||||||rs755771866|6.55644e-02|6.10034e-02|2.64117e-02|6.10034e-02|1.10104e-02|2.79881e-02|1.72733e-02|1.85768e-02|2.08117e-02|1.68539e-02,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs755771866|1|2966|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.02589|0.02678|0.0622|0.01097|0.02773|0.0171|0.01874|0.021|0.0167|0.0622|gnomAD_AMR|||||||||||||||rs755771866|6.55644e-02|6.10034e-02|2.64117e-02|6.10034e-02|1.10104e-02|2.79881e-02|1.72733e-02|1.85768e-02|2.08117e-02|1.68539e-02,G|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-7T>C|||||||rs755771866|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02589|0.02678|0.0622|0.01097|0.02773|0.0171|0.01874|0.021|0.0167|0.0622|gnomAD_AMR|||||||||||||||rs755771866|6.55644e-02|6.10034e-02|2.64117e-02|6.10034e-02|1.10104e-02|2.79881e-02|1.72733e-02|1.85768e-02|2.08117e-02|1.68539e-02,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-11T>C|||||||rs755771866|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02589|0.02678|0.0622|0.01097|0.02773|0.0171|0.01874|0.021|0.0167|0.0622|gnomAD_AMR|||||||||||||||rs755771866|6.55644e-02|6.10034e-02|2.64117e-02|6.10034e-02|1.10104e-02|2.79881e-02|1.72733e-02|1.85768e-02|2.08117e-02|1.68539e-02,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-11T>C|||||||rs755771866|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02589|0.02678|0.0622|0.01097|0.02773|0.0171|0.01874|0.021|0.0167|0.0622|gnomAD_AMR|||||||||||||||rs755771866|6.55644e-02|6.10034e-02|2.64117e-02|6.10034e-02|1.10104e-02|2.79881e-02|1.72733e-02|1.85768e-02|2.08117e-02|1.68539e-02 1 17378 . C T 51978.5 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-10G>A|||||||rs779725194|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003702|0.004158|0.0002729|0|0|0|0|0|0|0.004158|gnomAD_AFR|||||||||||||||rs779725194|1.35929e-03|4.13087e-03|4.13087e-03|2.71838e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-14G>A|||||||rs779725194|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.0003702|0.004158|0.0002729|0|0|0|0|0|0|0.004158|gnomAD_AFR|||||||||||||||rs779725194|1.35929e-03|4.13087e-03|4.13087e-03|2.71838e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs779725194|1|2969|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.0003702|0.004158|0.0002729|0|0|0|0|0|0|0.004158|gnomAD_AFR|||||||||||||||rs779725194|1.35929e-03|4.13087e-03|4.13087e-03|2.71838e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-10G>A|||||||rs779725194|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003702|0.004158|0.0002729|0|0|0|0|0|0|0.004158|gnomAD_AFR|||||||||||||||rs779725194|1.35929e-03|4.13087e-03|4.13087e-03|2.71838e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-14G>A|||||||rs779725194|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003702|0.004158|0.0002729|0|0|0|0|0|0|0.004158|gnomAD_AFR|||||||||||||||rs779725194|1.35929e-03|4.13087e-03|4.13087e-03|2.71838e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-14G>A|||||||rs779725194|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003702|0.004158|0.0002729|0|0|0|0|0|0|0.004158|gnomAD_AFR|||||||||||||||rs779725194|1.35929e-03|4.13087e-03|4.13087e-03|2.71838e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 17379 . G A 6071.09 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-11C>T|||||||rs754322362|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.002976|0.0006807|0.004802|0.003026|0.001418|0.0006526|0.003915|0.004813|0.003547|0.004813|gnomAD_OTH|||||||||||||||rs754322362|1.62535e-02|4.88630e-03|6.47668e-04|4.88630e-03|4.38048e-03|1.46520e-03|6.43856e-04|3.93539e-03|3.77358e-03|3.22165e-03,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-15C>T|||||||rs754322362|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.002976|0.0006807|0.004802|0.003026|0.001418|0.0006526|0.003915|0.004813|0.003547|0.004813|gnomAD_OTH|||||||||||||||rs754322362|1.62535e-02|4.88630e-03|6.47668e-04|4.88630e-03|4.38048e-03|1.46520e-03|6.43856e-04|3.93539e-03|3.77358e-03|3.22165e-03,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs754322362|1|2970|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.002976|0.0006807|0.004802|0.003026|0.001418|0.0006526|0.003915|0.004813|0.003547|0.004813|gnomAD_OTH|||||||||||||||rs754322362|1.62535e-02|4.88630e-03|6.47668e-04|4.88630e-03|4.38048e-03|1.46520e-03|6.43856e-04|3.93539e-03|3.77358e-03|3.22165e-03,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-11C>T|||||||rs754322362|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.002976|0.0006807|0.004802|0.003026|0.001418|0.0006526|0.003915|0.004813|0.003547|0.004813|gnomAD_OTH|||||||||||||||rs754322362|1.62535e-02|4.88630e-03|6.47668e-04|4.88630e-03|4.38048e-03|1.46520e-03|6.43856e-04|3.93539e-03|3.77358e-03|3.22165e-03,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-15C>T|||||||rs754322362|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.002976|0.0006807|0.004802|0.003026|0.001418|0.0006526|0.003915|0.004813|0.003547|0.004813|gnomAD_OTH|||||||||||||||rs754322362|1.62535e-02|4.88630e-03|6.47668e-04|4.88630e-03|4.38048e-03|1.46520e-03|6.43856e-04|3.93539e-03|3.77358e-03|3.22165e-03,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-15C>T|||||||rs754322362|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.002976|0.0006807|0.004802|0.003026|0.001418|0.0006526|0.003915|0.004813|0.003547|0.004813|gnomAD_OTH|||||||||||||||rs754322362|1.62535e-02|4.88630e-03|6.47668e-04|4.88630e-03|4.38048e-03|1.46520e-03|6.43856e-04|3.93539e-03|3.77358e-03|3.22165e-03 1 17385 . G A 143682 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-17C>T|||||||rs201535981|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.1731|0.1461|0.2216|0.2577|0.02786|0.2076|0.199|0.2156|0.1641|0.2577|gnomAD_ASJ|||||||||||||||rs201535981|2.04720e-01|2.21548e-01|1.44253e-01|2.21548e-01|2.53199e-01|2.80693e-02|2.07001e-01|1.99722e-01|1.99198e-01|1.62889e-01,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-21C>T|||||||rs201535981|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.1731|0.1461|0.2216|0.2577|0.02786|0.2076|0.199|0.2156|0.1641|0.2577|gnomAD_ASJ|||||||||||||||rs201535981|2.04720e-01|2.21548e-01|1.44253e-01|2.21548e-01|2.53199e-01|2.80693e-02|2.07001e-01|1.99722e-01|1.99198e-01|1.62889e-01,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201535981|1|2976|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.1731|0.1461|0.2216|0.2577|0.02786|0.2076|0.199|0.2156|0.1641|0.2577|gnomAD_ASJ|||||||||||||||rs201535981|2.04720e-01|2.21548e-01|1.44253e-01|2.21548e-01|2.53199e-01|2.80693e-02|2.07001e-01|1.99722e-01|1.99198e-01|1.62889e-01,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-17C>T|||||||rs201535981|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.1731|0.1461|0.2216|0.2577|0.02786|0.2076|0.199|0.2156|0.1641|0.2577|gnomAD_ASJ|||||||||||||||rs201535981|2.04720e-01|2.21548e-01|1.44253e-01|2.21548e-01|2.53199e-01|2.80693e-02|2.07001e-01|1.99722e-01|1.99198e-01|1.62889e-01,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-21C>T|||||||rs201535981|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.1731|0.1461|0.2216|0.2577|0.02786|0.2076|0.199|0.2156|0.1641|0.2577|gnomAD_ASJ|||||||||||||||rs201535981|2.04720e-01|2.21548e-01|1.44253e-01|2.21548e-01|2.53199e-01|2.80693e-02|2.07001e-01|1.99722e-01|1.99198e-01|1.62889e-01,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-21C>T|||||||rs201535981|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.1731|0.1461|0.2216|0.2577|0.02786|0.2076|0.199|0.2156|0.1641|0.2577|gnomAD_ASJ|||||||||||||||rs201535981|2.04720e-01|2.21548e-01|1.44253e-01|2.21548e-01|2.53199e-01|2.80693e-02|2.07001e-01|1.99722e-01|1.99198e-01|1.62889e-01 1 17398 . C A 578.35 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-30G>T|||||||rs200784459|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.00369|0.02113|0.006153|0.003397|0.006616|0.000283|0.000667|0.003538|0.0004701|0.02113|gnomAD_AFR|||||||||||||||rs200784459|1.21953e-02|2.03710e-02|2.03710e-02|5.84179e-03|2.79642e-03|6.63604e-03|1.85977e-04|6.92247e-04|3.66300e-03|7.81250e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-34G>T|||||||rs200784459|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.00369|0.02113|0.006153|0.003397|0.006616|0.000283|0.000667|0.003538|0.0004701|0.02113|gnomAD_AFR|||||||||||||||rs200784459|1.21953e-02|2.03710e-02|2.03710e-02|5.84179e-03|2.79642e-03|6.63604e-03|1.85977e-04|6.92247e-04|3.66300e-03|7.81250e-04,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs200784459|1|2989|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.00369|0.02113|0.006153|0.003397|0.006616|0.000283|0.000667|0.003538|0.0004701|0.02113|gnomAD_AFR|||||||||||||||rs200784459|1.21953e-02|2.03710e-02|2.03710e-02|5.84179e-03|2.79642e-03|6.63604e-03|1.85977e-04|6.92247e-04|3.66300e-03|7.81250e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-30G>T|||||||rs200784459|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.00369|0.02113|0.006153|0.003397|0.006616|0.000283|0.000667|0.003538|0.0004701|0.02113|gnomAD_AFR|||||||||||||||rs200784459|1.21953e-02|2.03710e-02|2.03710e-02|5.84179e-03|2.79642e-03|6.63604e-03|1.85977e-04|6.92247e-04|3.66300e-03|7.81250e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-34G>T|||||||rs200784459|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.00369|0.02113|0.006153|0.003397|0.006616|0.000283|0.000667|0.003538|0.0004701|0.02113|gnomAD_AFR|||||||||||||||rs200784459|1.21953e-02|2.03710e-02|2.03710e-02|5.84179e-03|2.79642e-03|6.63604e-03|1.85977e-04|6.92247e-04|3.66300e-03|7.81250e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-34G>T|||||||rs200784459|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.00369|0.02113|0.006153|0.003397|0.006616|0.000283|0.000667|0.003538|0.0004701|0.02113|gnomAD_AFR|||||||||||||||rs200784459|1.21953e-02|2.03710e-02|2.03710e-02|5.84179e-03|2.79642e-03|6.63604e-03|1.85977e-04|6.92247e-04|3.66300e-03|7.81250e-04 1 17403 . A G 455.96 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-35T>C|||||||rs111588939|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.001147|0.004752|0.001191|0.000672|0|0.0005683|0.000963|0|0.001426|0.004752|gnomAD_AFR|||||||||||||||rs111588939|4.60532e-03|5.03187e-03|5.03187e-03|1.00402e-03|5.54324e-04|0.00000e+00|5.60119e-04|9.55708e-04|4.56204e-04|1.42270e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-39T>C|||||||rs111588939|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.001147|0.004752|0.001191|0.000672|0|0.0005683|0.000963|0|0.001426|0.004752|gnomAD_AFR|||||||||||||||rs111588939|4.60532e-03|5.03187e-03|5.03187e-03|1.00402e-03|5.54324e-04|0.00000e+00|5.60119e-04|9.55708e-04|4.56204e-04|1.42270e-03,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs111588939|1|2994|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.001147|0.004752|0.001191|0.000672|0|0.0005683|0.000963|0|0.001426|0.004752|gnomAD_AFR|||||||||||||||rs111588939|4.60532e-03|5.03187e-03|5.03187e-03|1.00402e-03|5.54324e-04|0.00000e+00|5.60119e-04|9.55708e-04|4.56204e-04|1.42270e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-35T>C|||||||rs111588939|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.001147|0.004752|0.001191|0.000672|0|0.0005683|0.000963|0|0.001426|0.004752|gnomAD_AFR|||||||||||||||rs111588939|4.60532e-03|5.03187e-03|5.03187e-03|1.00402e-03|5.54324e-04|0.00000e+00|5.60119e-04|9.55708e-04|4.56204e-04|1.42270e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-39T>C|||||||rs111588939|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.001147|0.004752|0.001191|0.000672|0|0.0005683|0.000963|0|0.001426|0.004752|gnomAD_AFR|||||||||||||||rs111588939|4.60532e-03|5.03187e-03|5.03187e-03|1.00402e-03|5.54324e-04|0.00000e+00|5.60119e-04|9.55708e-04|4.56204e-04|1.42270e-03,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-39T>C|||||||rs111588939|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.001147|0.004752|0.001191|0.000672|0|0.0005683|0.000963|0|0.001426|0.004752|gnomAD_AFR|||||||||||||||rs111588939|4.60532e-03|5.03187e-03|5.03187e-03|1.00402e-03|5.54324e-04|0.00000e+00|5.60119e-04|9.55708e-04|4.56204e-04|1.42270e-03 1 17406 . C T 3174.92 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-38G>A|||||||rs772228657|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.008214|0.002293|0.03675|0.00517|0.002199|0.004492|0.003838|0.00492|0.006555|0.03675|gnomAD_AMR|||||||||||||||rs772228657|3.15176e-02|3.53156e-02|2.68817e-03|3.53156e-02|4.87211e-03|2.20210e-03|4.33498e-03|3.79606e-03|5.81395e-03|6.55022e-03,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-42G>A|||||||rs772228657|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.008214|0.002293|0.03675|0.00517|0.002199|0.004492|0.003838|0.00492|0.006555|0.03675|gnomAD_AMR|||||||||||||||rs772228657|3.15176e-02|3.53156e-02|2.68817e-03|3.53156e-02|4.87211e-03|2.20210e-03|4.33498e-03|3.79606e-03|5.81395e-03|6.55022e-03,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs772228657|1|2997|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.008214|0.002293|0.03675|0.00517|0.002199|0.004492|0.003838|0.00492|0.006555|0.03675|gnomAD_AMR|||||||||||||||rs772228657|3.15176e-02|3.53156e-02|2.68817e-03|3.53156e-02|4.87211e-03|2.20210e-03|4.33498e-03|3.79606e-03|5.81395e-03|6.55022e-03,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-38G>A|||||||rs772228657|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.008214|0.002293|0.03675|0.00517|0.002199|0.004492|0.003838|0.00492|0.006555|0.03675|gnomAD_AMR|||||||||||||||rs772228657|3.15176e-02|3.53156e-02|2.68817e-03|3.53156e-02|4.87211e-03|2.20210e-03|4.33498e-03|3.79606e-03|5.81395e-03|6.55022e-03,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-42G>A|||||||rs772228657|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.008214|0.002293|0.03675|0.00517|0.002199|0.004492|0.003838|0.00492|0.006555|0.03675|gnomAD_AMR|||||||||||||||rs772228657|3.15176e-02|3.53156e-02|2.68817e-03|3.53156e-02|4.87211e-03|2.20210e-03|4.33498e-03|3.79606e-03|5.81395e-03|6.55022e-03,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-42G>A|||||||rs772228657|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.008214|0.002293|0.03675|0.00517|0.002199|0.004492|0.003838|0.00492|0.006555|0.03675|gnomAD_AMR|||||||||||||||rs772228657|3.15176e-02|3.53156e-02|2.68817e-03|3.53156e-02|4.87211e-03|2.20210e-03|4.33498e-03|3.79606e-03|5.81395e-03|6.55022e-03 1 17407 . G A 17342.6 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-39C>T|||||||rs372841554|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02528|0.008621|0.01798|0.007009|0.02847|0.02827|0.02517|0.02573|0.05453|0.05453|gnomAD_SAS|||||||||||||||rs372841554|7.06559e-02|5.44346e-02|8.75044e-03|1.80180e-02|7.81250e-03|2.80962e-02|2.82222e-02|2.51466e-02|2.12882e-02|5.44346e-02,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-43C>T|||||||rs372841554|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.02528|0.008621|0.01798|0.007009|0.02847|0.02827|0.02517|0.02573|0.05453|0.05453|gnomAD_SAS|||||||||||||||rs372841554|7.06559e-02|5.44346e-02|8.75044e-03|1.80180e-02|7.81250e-03|2.80962e-02|2.82222e-02|2.51466e-02|2.12882e-02|5.44346e-02,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs372841554|1|2998|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.02528|0.008621|0.01798|0.007009|0.02847|0.02827|0.02517|0.02573|0.05453|0.05453|gnomAD_SAS|||||||||||||||rs372841554|7.06559e-02|5.44346e-02|8.75044e-03|1.80180e-02|7.81250e-03|2.80962e-02|2.82222e-02|2.51466e-02|2.12882e-02|5.44346e-02,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-39C>T|||||||rs372841554|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02528|0.008621|0.01798|0.007009|0.02847|0.02827|0.02517|0.02573|0.05453|0.05453|gnomAD_SAS|||||||||||||||rs372841554|7.06559e-02|5.44346e-02|8.75044e-03|1.80180e-02|7.81250e-03|2.80962e-02|2.82222e-02|2.51466e-02|2.12882e-02|5.44346e-02,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-43C>T|||||||rs372841554|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02528|0.008621|0.01798|0.007009|0.02847|0.02827|0.02517|0.02573|0.05453|0.05453|gnomAD_SAS|||||||||||||||rs372841554|7.06559e-02|5.44346e-02|8.75044e-03|1.80180e-02|7.81250e-03|2.80962e-02|2.82222e-02|2.51466e-02|2.12882e-02|5.44346e-02,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-43C>T|||||||rs372841554|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.02528|0.008621|0.01798|0.007009|0.02847|0.02827|0.02517|0.02573|0.05453|0.05453|gnomAD_SAS|||||||||||||||rs372841554|7.06559e-02|5.44346e-02|8.75044e-03|1.80180e-02|7.81250e-03|2.80962e-02|2.82222e-02|2.51466e-02|2.12882e-02|5.44346e-02 1 17408 . 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C A 1665.32 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-59G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs1226211126|2.44226e-05|2.55258e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.55258e-05|0.00000e+00|0.00000e+00,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-63G>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1226211126|2.44226e-05|2.55258e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.55258e-05|0.00000e+00|0.00000e+00,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3018|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1226211126|2.44226e-05|2.55258e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.55258e-05|0.00000e+00|0.00000e+00,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-59G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs1226211126|2.44226e-05|2.55258e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.55258e-05|0.00000e+00|0.00000e+00,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-63G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs1226211126|2.44226e-05|2.55258e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.55258e-05|0.00000e+00|0.00000e+00,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.547-63G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||rs1226211126|2.44226e-05|2.55258e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.55258e-05|0.00000e+00|0.00000e+00 1 17444 . 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G A 65.27 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-85C>T|||||||rs776816361|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003978|0|0.0001265|0|0.003183|0|9.102e-05|0.0007941|0.0006742|0.003183|gnomAD_EAS|||||||||||||||rs776816361|9.57249e-04|3.17520e-03|0.00000e+00|1.22810e-04|0.00000e+00|3.17520e-03|0.00000e+00|6.89061e-05|6.99301e-04|6.75980e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-89C>T|||||||rs776816361|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.0003978|0|0.0001265|0|0.003183|0|9.102e-05|0.0007941|0.0006742|0.003183|gnomAD_EAS|||||||||||||||rs776816361|9.57249e-04|3.17520e-03|0.00000e+00|1.22810e-04|0.00000e+00|3.17520e-03|0.00000e+00|6.89061e-05|6.99301e-04|6.75980e-04,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs776816361|1|3044|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.0003978|0|0.0001265|0|0.003183|0|9.102e-05|0.0007941|0.0006742|0.003183|gnomAD_EAS|||||||||||||||rs776816361|9.57249e-04|3.17520e-03|0.00000e+00|1.22810e-04|0.00000e+00|3.17520e-03|0.00000e+00|6.89061e-05|6.99301e-04|6.75980e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-85C>T|||||||rs776816361|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003978|0|0.0001265|0|0.003183|0|9.102e-05|0.0007941|0.0006742|0.003183|gnomAD_EAS|||||||||||||||rs776816361|9.57249e-04|3.17520e-03|0.00000e+00|1.22810e-04|0.00000e+00|3.17520e-03|0.00000e+00|6.89061e-05|6.99301e-04|6.75980e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-89C>T|||||||rs776816361|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003978|0|0.0001265|0|0.003183|0|9.102e-05|0.0007941|0.0006742|0.003183|gnomAD_EAS|||||||||||||||rs776816361|9.57249e-04|3.17520e-03|0.00000e+00|1.22810e-04|0.00000e+00|3.17520e-03|0.00000e+00|6.89061e-05|6.99301e-04|6.75980e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+45C>T|||||||rs776816361|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003978|0|0.0001265|0|0.003183|0|9.102e-05|0.0007941|0.0006742|0.003183|gnomAD_EAS|||||||||||||||rs776816361|9.57249e-04|3.17520e-03|0.00000e+00|1.22810e-04|0.00000e+00|3.17520e-03|0.00000e+00|6.89061e-05|6.99301e-04|6.75980e-04 1 17455 . GC G 110.07 PASS CSQ=-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-88del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||1:17456-17457|4.26178e-06|1.71403e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.71403e-05|0.00000e+00|0.00000e+00,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-92del||||||||1||-1||deletion|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||1:17456-17457|4.26178e-06|1.71403e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.71403e-05|0.00000e+00|0.00000e+00,-|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3047|1||deletion|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||1:17456-17457|4.26178e-06|1.71403e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.71403e-05|0.00000e+00|0.00000e+00,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-88del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||1:17456-17457|4.26178e-06|1.71403e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.71403e-05|0.00000e+00|0.00000e+00,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-92del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||1:17456-17457|4.26178e-06|1.71403e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.71403e-05|0.00000e+00|0.00000e+00,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+42del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||1:17456-17457|4.26178e-06|1.71403e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.71403e-05|0.00000e+00|0.00000e+00 1 17478 . C T 445.52 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-110G>A|||||||rs766005794|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.000185|0.0008242|0.0004173|0.001119|0|0|3.446e-05|0.0002555|0|0.001119|gnomAD_ASJ|||||||||||||||rs766005794|7.23798e-04|9.23727e-04|9.23727e-04|4.04989e-04|9.62927e-04|0.00000e+00|0.00000e+00|6.55351e-05|4.49236e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-114G>A|||||||rs766005794|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.000185|0.0008242|0.0004173|0.001119|0|0|3.446e-05|0.0002555|0|0.001119|gnomAD_ASJ|||||||||||||||rs766005794|7.23798e-04|9.23727e-04|9.23727e-04|4.04989e-04|9.62927e-04|0.00000e+00|0.00000e+00|6.55351e-05|4.49236e-04|0.00000e+00,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs766005794|1|3069|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.000185|0.0008242|0.0004173|0.001119|0|0|3.446e-05|0.0002555|0|0.001119|gnomAD_ASJ|||||||||||||||rs766005794|7.23798e-04|9.23727e-04|9.23727e-04|4.04989e-04|9.62927e-04|0.00000e+00|0.00000e+00|6.55351e-05|4.49236e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-110G>A|||||||rs766005794|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.000185|0.0008242|0.0004173|0.001119|0|0|3.446e-05|0.0002555|0|0.001119|gnomAD_ASJ|||||||||||||||rs766005794|7.23798e-04|9.23727e-04|9.23727e-04|4.04989e-04|9.62927e-04|0.00000e+00|0.00000e+00|6.55351e-05|4.49236e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-114G>A|||||||rs766005794|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.000185|0.0008242|0.0004173|0.001119|0|0|3.446e-05|0.0002555|0|0.001119|gnomAD_ASJ|||||||||||||||rs766005794|7.23798e-04|9.23727e-04|9.23727e-04|4.04989e-04|9.62927e-04|0.00000e+00|0.00000e+00|6.55351e-05|4.49236e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+20G>A|||||||rs766005794|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.000185|0.0008242|0.0004173|0.001119|0|0|3.446e-05|0.0002555|0|0.001119|gnomAD_ASJ|||||||||||||||rs766005794|7.23798e-04|9.23727e-04|9.23727e-04|4.04989e-04|9.62927e-04|0.00000e+00|0.00000e+00|6.55351e-05|4.49236e-04|0.00000e+00 1 17479 . G A 1705.6 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-111C>T|||||||rs755400445|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003228|0.003805|0.0002089|0.000244|9.711e-05|0.0001189|5.135e-05|0.0002539|0.0003467|0.003805|gnomAD_AFR|||||||||||||||rs755400445|1.62107e-03|3.78993e-03|3.78993e-03|2.43132e-04|2.36407e-04|0.00000e+00|1.17661e-04|3.25882e-05|0.00000e+00|3.04136e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.605-115C>T|||||||rs755400445|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.0003228|0.003805|0.0002089|0.000244|9.711e-05|0.0001189|5.135e-05|0.0002539|0.0003467|0.003805|gnomAD_AFR|||||||||||||||rs755400445|1.62107e-03|3.78993e-03|3.78993e-03|2.43132e-04|2.36407e-04|0.00000e+00|1.17661e-04|3.25882e-05|0.00000e+00|3.04136e-04,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs755400445|1|3070|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.0003228|0.003805|0.0002089|0.000244|9.711e-05|0.0001189|5.135e-05|0.0002539|0.0003467|0.003805|gnomAD_AFR|||||||||||||||rs755400445|1.62107e-03|3.78993e-03|3.78993e-03|2.43132e-04|2.36407e-04|0.00000e+00|1.17661e-04|3.25882e-05|0.00000e+00|3.04136e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-111C>T|||||||rs755400445|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003228|0.003805|0.0002089|0.000244|9.711e-05|0.0001189|5.135e-05|0.0002539|0.0003467|0.003805|gnomAD_AFR|||||||||||||||rs755400445|1.62107e-03|3.78993e-03|3.78993e-03|2.43132e-04|2.36407e-04|0.00000e+00|1.17661e-04|3.25882e-05|0.00000e+00|3.04136e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.816-115C>T|||||||rs755400445|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003228|0.003805|0.0002089|0.000244|9.711e-05|0.0001189|5.135e-05|0.0002539|0.0003467|0.003805|gnomAD_AFR|||||||||||||||rs755400445|1.62107e-03|3.78993e-03|3.78993e-03|2.43132e-04|2.36407e-04|0.00000e+00|1.17661e-04|3.25882e-05|0.00000e+00|3.04136e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+19C>T|||||||rs755400445|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0003228|0.003805|0.0002089|0.000244|9.711e-05|0.0001189|5.135e-05|0.0002539|0.0003467|0.003805|gnomAD_AFR|||||||||||||||rs755400445|1.62107e-03|3.78993e-03|3.78993e-03|2.43132e-04|2.36407e-04|0.00000e+00|1.17661e-04|3.25882e-05|0.00000e+00|3.04136e-04 1 17483 . C T 5193.49 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-115G>A|||||||rs765660047|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0002874|0.0009264|0.0007521|0|0|0.0001778|0.0001863|0.001264|0|0.001264|gnomAD_OTH|||||||||||||||rs765660047|1.09456e-03|8.92629e-04|8.92629e-04|7.29513e-04|0.00000e+00|0.00000e+00|2.93531e-04|1.45490e-04|4.45434e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+119G>A|||||||rs765660047|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.0002874|0.0009264|0.0007521|0|0|0.0001778|0.0001863|0.001264|0|0.001264|gnomAD_OTH|||||||||||||||rs765660047|1.09456e-03|8.92629e-04|8.92629e-04|7.29513e-04|0.00000e+00|0.00000e+00|2.93531e-04|1.45490e-04|4.45434e-04|0.00000e+00,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs765660047|1|3074|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.0002874|0.0009264|0.0007521|0|0|0.0001778|0.0001863|0.001264|0|0.001264|gnomAD_OTH|||||||||||||||rs765660047|1.09456e-03|8.92629e-04|8.92629e-04|7.29513e-04|0.00000e+00|0.00000e+00|2.93531e-04|1.45490e-04|4.45434e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-115G>A|||||||rs765660047|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0002874|0.0009264|0.0007521|0|0|0.0001778|0.0001863|0.001264|0|0.001264|gnomAD_OTH|||||||||||||||rs765660047|1.09456e-03|8.92629e-04|8.92629e-04|7.29513e-04|0.00000e+00|0.00000e+00|2.93531e-04|1.45490e-04|4.45434e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+119G>A|||||||rs765660047|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0002874|0.0009264|0.0007521|0|0|0.0001778|0.0001863|0.001264|0|0.001264|gnomAD_OTH|||||||||||||||rs765660047|1.09456e-03|8.92629e-04|8.92629e-04|7.29513e-04|0.00000e+00|0.00000e+00|2.93531e-04|1.45490e-04|4.45434e-04|0.00000e+00,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+15G>A|||||||rs765660047|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0002874|0.0009264|0.0007521|0|0|0.0001778|0.0001863|0.001264|0|0.001264|gnomAD_OTH|||||||||||||||rs765660047|1.09456e-03|8.92629e-04|8.92629e-04|7.29513e-04|0.00000e+00|0.00000e+00|2.93531e-04|1.45490e-04|4.45434e-04|0.00000e+00 1 17484 . G A 4540.86 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.489-116C>T|||||||rs753281850|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0007451|0.001852|0.0002082|0|9.686e-05|0.002718|0.0007271|0|0.0002587|0.002718|gnomAD_FIN|||||||||||||||rs753281850|2.33829e-03|1.65901e-03|1.65901e-03|2.01939e-04|0.00000e+00|9.08430e-05|2.75251e-03|7.10136e-04|0.00000e+00|2.59336e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+118C>T|||||||rs753281850|1||-1||SNV|HGNC|38034|YES|||||||||||||||||||||||0.0007451|0.001852|0.0002082|0|9.686e-05|0.002718|0.0007271|0|0.0002587|0.002718|gnomAD_FIN|||||||||||||||rs753281850|2.33829e-03|1.65901e-03|1.65901e-03|2.01939e-04|0.00000e+00|9.08430e-05|2.75251e-03|7.10136e-04|0.00000e+00|2.59336e-04,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs753281850|1|3075|1||SNV|HGNC|37102|YES|||||||||||||||||||||||0.0007451|0.001852|0.0002082|0|9.686e-05|0.002718|0.0007271|0|0.0002587|0.002718|gnomAD_FIN|||||||||||||||rs753281850|2.33829e-03|1.65901e-03|1.65901e-03|2.01939e-04|0.00000e+00|9.08430e-05|2.75251e-03|7.10136e-04|0.00000e+00|2.59336e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.575-116C>T|||||||rs753281850|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0007451|0.001852|0.0002082|0|9.686e-05|0.002718|0.0007271|0|0.0002587|0.002718|gnomAD_FIN|||||||||||||||rs753281850|2.33829e-03|1.65901e-03|1.65901e-03|2.01939e-04|0.00000e+00|9.08430e-05|2.75251e-03|7.10136e-04|0.00000e+00|2.59336e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+118C>T|||||||rs753281850|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0007451|0.001852|0.0002082|0|9.686e-05|0.002718|0.0007271|0|0.0002587|0.002718|gnomAD_FIN|||||||||||||||rs753281850|2.33829e-03|1.65901e-03|1.65901e-03|2.01939e-04|0.00000e+00|9.08430e-05|2.75251e-03|7.10136e-04|0.00000e+00|2.59336e-04,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+14C>T|||||||rs753281850|1||-1||SNV|HGNC|38034||||||||||||||||||||||||0.0007451|0.001852|0.0002082|0|9.686e-05|0.002718|0.0007271|0|0.0002587|0.002718|gnomAD_FIN|||||||||||||||rs753281850|2.33829e-03|1.65901e-03|1.65901e-03|2.01939e-04|0.00000e+00|9.08430e-05|2.75251e-03|7.10136e-04|0.00000e+00|2.59336e-04 1 17487 . C A 230.1 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+119G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+115G>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3078|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+119G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+115G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+11G>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17490 . C T 392.34 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+116G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+112G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3081|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+116G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+112G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+8G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17493 . G A 576.4 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+113C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+109C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3084|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+113C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+109C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||5/8|ENST00000541675.1:n.546+5C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17501 . CT C 1756.44 PASS CSQ=-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+104del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+100del||||||||1||-1||deletion|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3093|1||deletion|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+104del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+100del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|5/9||ENST00000541675.1:n.542del||542||||||1||-1||deletion|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17512 . C G 1690 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+94G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+90G>C||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3103|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+94G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+90G>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-8G>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17516 . T C 195.52 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+90A>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+86A>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3107|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+90A>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+86A>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-12A>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17519 . G T 41009.7 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+87C>A|||||||rs192890528|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+83C>A|||||||rs192890528|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs192890528|1|3110|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+87C>A|||||||rs192890528|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+83C>A|||||||rs192890528|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-15C>A|||||||rs192890528|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17527 . T A 183.94 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+79A>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+75A>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3118|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+79A>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+75A>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-23A>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17528 . G C 95.53 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+78C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+74C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3119|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+78C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+74C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-24C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17538 . C A 832954 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+68G>T|||||||rs71260068|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+64G>T|||||||rs71260068|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs71260068|1|3129|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+68G>T|||||||rs71260068|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+64G>T|||||||rs71260068|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-34G>T|||||||rs71260068|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17540 . C A 114.11 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+66G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+62G>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3131|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+66G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+62G>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.540-36G>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17556 . C T 28118.1 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+50G>A|||||||rs374545136|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+46G>A|||||||rs374545136|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs374545136|1|3147|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+50G>A|||||||rs374545136|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+46G>A|||||||rs374545136|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+50G>A|||||||rs374545136|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17559 . G C 1813.25 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+47C>G|||||||rs866150608|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+43C>G|||||||rs866150608|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs866150608|1|3150|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+47C>G|||||||rs866150608|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+43C>G|||||||rs866150608|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+47C>G|||||||rs866150608|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17562 . C T 170.38 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+44G>A|||||||rs867709223|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+40G>A|||||||rs867709223|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs867709223|1|3153|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+44G>A|||||||rs867709223|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+40G>A|||||||rs867709223|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+44G>A|||||||rs867709223|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17563 . G A 412.94 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+43C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+39C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3154|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+43C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+39C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+43C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17585 . G A 38.28 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+21C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+17C>T||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3176|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+21C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+17C>T||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+21C>T||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17589 . C T 71.8 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+17G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+13G>A||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3180|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+17G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+13G>A||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+17G>A||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17594 . C T 49655.2 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||4/9|ENST00000423562.1:n.488+12G>A|||||||rs377698370|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||5/11|ENST00000438504.2:n.604+8G>A|||||||rs377698370|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs377698370|1|3185|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||5/10|ENST00000488147.1:n.574+12G>A|||||||rs377698370|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||5/12|ENST00000538476.1:n.815+8G>A|||||||rs377698370|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||4/8|ENST00000541675.1:n.539+12G>A|||||||rs377698370|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17606 . A G 95.24 PASS CSQ=G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.488T>C||488||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.600T>C||600||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3197|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.574T>C||574||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.811T>C||811||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|splice_region_variant&non_coding_transcript_exon_variant|LOW|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.539T>C||539||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17614 . G A 89621.7 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.480C>T||480|||||rs201057270|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.592C>T||592|||||rs201057270|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs201057270|1|3205|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.566C>T||566|||||rs201057270|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.803C>T||803|||||rs201057270|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.531C>T||531|||||rs201057270|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17626 . G A 29061.4 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.468C>T||468||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.580C>T||580||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3217|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.554C>T||554||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.791C>T||791||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.519C>T||519||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17636 . G A 105.97 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.458C>T||458||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.570C>T||570||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3227|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.544C>T||544||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.781C>T||781||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.509C>T||509||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17639 . C A 35.57 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.455G>T||455||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.567G>T||567||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3230|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.541G>T||541||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.778G>T||778||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.506G>T||506||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17645 . G C 100.74 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.449C>G||449||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.561C>G||561||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3236|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.535C>G||535||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.772C>G||772||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.500C>G||500||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17647 . GC G 180.74 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.446del||446||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.558del||558||||||1||-1||deletion|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3239|1||deletion|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.532del||532||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.769del||769||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.497del||497||||||1||-1||deletion|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17652 . T C 69.59 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.442A>G||442||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.554A>G||554||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3243|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.528A>G||528||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.765A>G||765||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.493A>G||493||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17694 . C T 97.08 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.400G>A||400|||||rs563880190|1||-1||SNV|HGNC|38034||||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.512G>A||512|||||rs563880190|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs563880190|1|3285|1||SNV|HGNC|37102|YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.486G>A||486|||||rs563880190|1||-1||SNV|HGNC|38034||||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.723G>A||723|||||rs563880190|1||-1||SNV|HGNC|38034||||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.451G>A||451|||||rs563880190|1||-1||SNV|HGNC|38034||||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS||||||||||||||||||||||||| 1 17695 . G A 43.02 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.399C>T||399|||||rs574335987|1||-1||SNV|HGNC|38034||||||||||||||||0.0008|0.0008|0.0029|0|0|0.001||||||||||||0.0029|AMR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.511C>T||511|||||rs574335987|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0008|0.0008|0.0029|0|0|0.001||||||||||||0.0029|AMR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs574335987|1|3286|1||SNV|HGNC|37102|YES|||||||||||||||0.0008|0.0008|0.0029|0|0|0.001||||||||||||0.0029|AMR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.485C>T||485|||||rs574335987|1||-1||SNV|HGNC|38034||||||||||||||||0.0008|0.0008|0.0029|0|0|0.001||||||||||||0.0029|AMR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.722C>T||722|||||rs574335987|1||-1||SNV|HGNC|38034||||||||||||||||0.0008|0.0008|0.0029|0|0|0.001||||||||||||0.0029|AMR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.450C>T||450|||||rs574335987|1||-1||SNV|HGNC|38034||||||||||||||||0.0008|0.0008|0.0029|0|0|0.001||||||||||||0.0029|AMR||||||||||||||||||||||||| 1 17697 . G C 62450.4 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.397C>G||397|||||rs71260069|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.509C>G||509|||||rs71260069|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs71260069|1|3288|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.483C>G||483|||||rs71260069|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.720C>G||720|||||rs71260069|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.448C>G||448|||||rs71260069|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17701 . C T 425.86 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.393G>A||393||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.505G>A||505||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3292|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.479G>A||479||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.716G>A||716||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.444G>A||444||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17709 . T G 73.58 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.385A>C||385|||||rs543363182|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.497A>C||497|||||rs543363182|1||-1||SNV|HGNC|38034|YES|||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs543363182|1|3300|1||SNV|HGNC|37102|YES|||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.471A>C||471|||||rs543363182|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.708A>C||708|||||rs543363182|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.436A>C||436|||||rs543363182|1||-1||SNV|HGNC|38034||||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS||||||||||||||||||||||||| 1 17716 . G A 1835.6 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.378C>T||378||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.490C>T||490||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|3307|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.464C>T||464||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.701C>T||701||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.429C>T||429||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17722 . A G 13686 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.372T>C||372|||||rs376731495|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.484T>C||484|||||rs376731495|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs376731495|1|3313|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.458T>C||458|||||rs376731495|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.695T>C||695|||||rs376731495|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.423T>C||423|||||rs376731495|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17728 . G T 162.69 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene|4/10||ENST00000423562.1:n.366C>A||366|||||rs868563840|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene|5/12||ENST00000438504.2:n.478C>A||478|||||rs868563840|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs868563840|1|3319|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene|5/11||ENST00000488147.1:n.452C>A||452|||||rs868563840|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene|5/13||ENST00000538476.1:n.689C>A||689|||||rs868563840|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene|4/9||ENST00000541675.1:n.417C>A||417|||||rs868563840|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17730 . 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G A 3646.02 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||3/9|ENST00000423562.1:n.352-23C>T|||||||rs373918278|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||4/11|ENST00000438504.2:n.464-23C>T|||||||rs373918278|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs373918278|1|3356|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||4/10|ENST00000488147.1:n.438-23C>T|||||||rs373918278|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||4/12|ENST00000538476.1:n.675-23C>T|||||||rs373918278|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||3/8|ENST00000541675.1:n.403-23C>T|||||||rs373918278|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17805 . T C 116.1 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||3/9|ENST00000423562.1:n.352-63A>G|||||||rs367778176|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||4/11|ENST00000438504.2:n.464-63A>G|||||||rs367778176|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs367778176|1|3396|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||4/10|ENST00000488147.1:n.438-63A>G|||||||rs367778176|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||4/12|ENST00000538476.1:n.675-63A>G|||||||rs367778176|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||3/8|ENST00000541675.1:n.403-63A>G|||||||rs367778176|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 17829 . G A 32.03 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||3/9|ENST00000423562.1:n.351+86C>T|||||||rs751079828|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||4/11|ENST00000438504.2:n.463+86C>T|||||||rs751079828|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs751079828|1|3420|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||4/10|ENST00000488147.1:n.437+86C>T|||||||rs751079828|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||4/12|ENST00000538476.1:n.674+86C>T|||||||rs751079828|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||3/8|ENST00000541675.1:n.402+86C>T|||||||rs751079828|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19190 . GC G 428.97 PASS CSQ=-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1130del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-812del||||||||1||-1||deletion|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|4782|1||deletion|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-825del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-825del||||||||1||-1||deletion|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-822del||||||||1||-1||deletion|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19217 . G C 105616 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1156C>G|||||||rs879518682|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-838C>G|||||||rs879518682|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs879518682|1|4808|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-851C>G|||||||rs879518682|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-851C>G|||||||rs879518682|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-848C>G|||||||rs879518682|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19226 . T A 998.17 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1165A>T|||||||rs62636376|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-847A>T|||||||rs62636376|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs62636376|1|4817|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-860A>T|||||||rs62636376|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-860A>T|||||||rs62636376|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-857A>T|||||||rs62636376|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19234 . A G 53.34 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1173T>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-855T>C||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|4825|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-868T>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-868T>C||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-865T>C||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19236 . G C 58.26 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1175C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-857C>G||||||||1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript|||||||||||1|4827|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-870C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-870C>G||||||||1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-867C>G||||||||1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19249 . G A 91992.1 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1188C>T|||||||rs879368491|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-870C>T|||||||rs879368491|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs879368491|1|4840|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-883C>T|||||||rs879368491|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-883C>T|||||||rs879368491|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-880C>T|||||||rs879368491|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 19254 . G C 6322.25 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000423562|unprocessed_pseudogene||2/9|ENST00000423562.1:n.205-1193C>G|||||||rs879460869|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000438504|unprocessed_pseudogene||2/11|ENST00000438504.2:n.205-875C>G|||||||rs879460869|1||-1||SNV|HGNC|38034|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|DDX11L1|ENSG00000223972|Transcript|ENST00000456328|processed_transcript||||||||||rs879460869|1|4845|1||SNV|HGNC|37102|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000488147|unprocessed_pseudogene||2/10|ENST00000488147.1:n.192-888C>G|||||||rs879460869|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000538476|unprocessed_pseudogene||2/12|ENST00000538476.1:n.429-888C>G|||||||rs879460869|1||-1||SNV|HGNC|38034|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|WASH7P|ENSG00000227232|Transcript|ENST00000541675|unprocessed_pseudogene||1/8|ENST00000541675.1:n.154-885C>G|||||||rs879460869|1||-1||SNV|HGNC|38034||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 62904 . C T 254.17 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|44|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 62905 . G A 461.36 PASS CSQ=A|upstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene||||||||||rs530999379|1|43|1||SNV|HGNC|31276|YES|||||||||||||||0.0006|0.0008|0.0029|0|0|0||||||||||||0.0029|AMR||||||||||||||||||||||||| 1 62926 . A G 247.95 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|22|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 62950 . T C 141.97 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.3T>C||3||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 62966 . C T 39.35 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.19C>T||19||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63093 . G A 90639.9 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.146G>A||146|||||rs200092917|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0341|0.0144|0.0086|0.0238|0.003|0.1217||||||||||||0.1217|SAS||||||||||||||||||||||||| 1 63165 . C T 188.65 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.218C>T||218||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63210 . G T 1540.52 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.263G>T||263|||||rs757089453|1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63212 . T C 227.2 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.265T>C||265|||||rs536685845|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 63307 . A G 60.87 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.360A>G||360||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63336 . C T 88506.7 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.389C>T||389|||||rs62639100|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0056|0.0008|0.0086|0|0.0199|0.001||||||||||||0.0199|EUR||||||||||||||||||||||||| 1 63415 . C T 55204.4 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.468C>T||468||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63437 . C G 191.71 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.490C>G||490|||||rs545343977|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0014|0|0|0|0|0.0072||||||||||||0.0072|SAS||||||||||||||||||||||||| 1 63458 . C T 102.14 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.511C>T||511||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63495 . C T 966.57 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.548C>T||548|||||rs200312425|1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63516 . A G 608.04 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.569A>G||569|||||rs62639101|1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63527 . T C 17334.8 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.580T>C||580||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63528 . G A 558.95 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.581G>A||581|||||rs879649520|1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63615 . G C 41611.7 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.668G>C||668||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63627 . C A 357 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.680C>A||680||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63628 . G A 188.98 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.681G>A||681||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63642 . G T 36354.3 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.695G>T||695||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63643 . A G 135114 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.696A>G||696|||||rs202004563|1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63654 . G A 403.77 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.707G>A||707||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63668 . G A 30089.7 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.721G>A||721|||||rs561430336|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 63671 . G A 744930 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.724G>A||724|||||rs80011619|1||1||SNV|HGNC|31276|YES|||||||||||||||0.1875|0.3654|0.183|0.0377|0.1044|0.1902||||||||||||0.3654|AFR||||||||||||||||||||||||| 1 63687 . G A 449.88 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.740G>A||740||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63697 . T C 579030 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.750T>C||750|||||rs111440589|1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63703 . C T 138.04 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.756C>T||756||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63708 . T C 122.88 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.761T>C||761||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63714 . T C 31.31 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.767T>C||767|||||rs566737183|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 63717 . C T 215.39 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.770C>T||770||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63722 . C T 78906.3 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.775C>T||775|||||rs552815263|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0034|0.0015|0.0101|0|0.007|0.001||||||||||||0.0101|AMR||||||||||||||||||||||||| 1 63735 . CCTA C 385420 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.792_794del||789-791|||||rs201888535|1||1||deletion|HGNC|31276|YES||||||||||||||3|0.3718|0.1074|0.2997|0.7292|0.339|0.4458||||||||||||0.7292|EAS||||||||||||||||||||||||| 1 63778 . T A 165.72 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.831T>A||831||||||1||1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 63791 . C T 344.87 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|1/1||ENST00000492842.1:n.844C>T||844|||||rs569253857|1||1||SNV|HGNC|31276|YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 65797 . T C 588.53 PASS CSQ=C|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding||||||||||rs759525926|1|3294|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene||||||||||rs759525926|1|1910|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65843 . G A 201.85 PASS CSQ=A|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3248|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|1956|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65851 . C T 509.13 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3240|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|1964|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65864 . A G 188.38 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3227|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|1977|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65868 . C T 42.02 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3223|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|1981|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65872 . T G 18895.2 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding||||||||||rs796239852|1|3219|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene||||||||||rs796239852|1|1985|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65875 . C T 117.09 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3216|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|1988|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65892 . C T 71.87 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3199|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2005|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65898 . T C 2823.61 PASS CSQ=C|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding||||||||||rs866936632|1|3193|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene||||||||||rs866936632|1|2011|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65900 . T C 117.86 PASS CSQ=C|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3191|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2013|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65907 . C T 218.76 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3184|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2020|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65910 . C G 66.96 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3181|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2023|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65918 . C T 104.94 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3173|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2031|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65973 . T C 1228.22 PASS CSQ=C|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3118|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2086|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65974 . A G 10257.9 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding||||||||||rs531923826|1|3117|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1||||||||0.0138|0.0484|0.0072|0|0|0||||||||||||0.0484|AFR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene||||||||||rs531923826|1|2087|1||SNV|HGNC|31276|YES|||||||||||||||0.0138|0.0484|0.0072|0|0|0||||||||||||0.0484|AFR||||||||||||||||||||||||| 1 65975 . C T 206.4 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3116|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2088|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 65992 . G A 678.67 PASS CSQ=A|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3099|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2105|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 66026 . A T 88.77 PASS CSQ=T|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3065|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2139|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 66041 . A G 138.44 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3050|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2154|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 66042 . G A,C 682.65 PASS CSQ=A|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3049|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||2|3049|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2155|1||SNV|HGNC|31276|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||2|2155|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 66053 . G A 65.5 PASS CSQ=A|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3038|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2166|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 66055 . C G 576.85 PASS CSQ=G|upstream_gene_variant|MODIFIER|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|||||||||||1|3036|1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|OR4G11P|ENSG00000240361|Transcript|ENST00000492842|unprocessed_pseudogene|||||||||||1|2168|1||SNV|HGNC|31276|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 69270 . A G 64453.2 PASS CSQ=G|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.180A>G|ENSP00000334393.3:p.Ser60%3D|180|180|60|S|tcA/tcG|rs201219564|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Low_complexity_(Seg):seg&Transmembrane_helices:TMhelix&Prints_domain:PR00237&PROSITE_profiles:PS50262|||||||||||0.8327|0.3603|0.7916|0.8434|0.9983|0.877|0.9112|0.8481|0.9018|0.9983|gnomAD_EAS|||||||||||||||rs201219564|7.81540e-01|9.98354e-01|3.59079e-01|7.93243e-01|8.48238e-01|9.98354e-01|8.82051e-01|9.14571e-01|8.68043e-01|9.00541e-01,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs201219564|1||||SNV||||||||||||||||||||||||||0.8327|0.3603|0.7916|0.8434|0.9983|0.877|0.9112|0.8481|0.9018|0.9983|gnomAD_EAS|||||||||||||||rs201219564|7.81540e-01|9.98354e-01|3.59079e-01|7.93243e-01|8.48238e-01|9.98354e-01|8.82051e-01|9.14571e-01|8.68043e-01|9.00541e-01 1 69428 . T G 455238 PASS CSQ=G|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.338T>G|ENSP00000334393.3:p.Phe113Cys|338|338|113|F/C|tTt/tGt|rs140739101|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.01)|probably_damaging(0.984)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00237&PROSITE_patterns:PS00237&PROSITE_profiles:PS50262|||0.0190|0.0015|0.036|0.003|0.0497|0.0153|0.003663|0.04571|0.02436|0.003129|0.009178|0.01338|0|0.04895|0.04092|0.02573|0.004991|0.0497|EUR|||||||||||||||rs140739101|2.15376e-02|4.17497e-02|3.34821e-03|9.05886e-03|1.39643e-02|0.00000e+00|4.83761e-02|4.17497e-02|2.93512e-02|4.97165e-03,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs140739101|1||||SNV||||||||||||||||||0.0190|0.0015|0.036|0.003|0.0497|0.0153|0.003663|0.04571|0.02436|0.003129|0.009178|0.01338|0|0.04895|0.04092|0.02573|0.004991|0.0497|EUR|||||||||||||||rs140739101|2.15376e-02|4.17497e-02|3.34821e-03|9.05886e-03|1.39643e-02|0.00000e+00|4.83761e-02|4.17497e-02|2.93512e-02|4.97165e-03 1 69438 . T C 28054.4 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.348T>C|ENSP00000334393.3:p.Tyr116%3D|348|348|116|Y|taT/taC|rs758790416|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Prints_domain:PR00237&PROSITE_patterns:PS00237&PROSITE_profiles:PS50262|||||||||||0.0001165|0|0|0|0|0|0.0002685|0|0|0.0002685|gnomAD_NFE|||||||||||||||rs758790416|9.66548e-05|2.64028e-04|0.00000e+00|9.71062e-05|0.00000e+00|0.00000e+00|0.00000e+00|2.64028e-04|0.00000e+00|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs758790416|1||||SNV||||||||||||||||||||||||||0.0001165|0|0|0|0|0|0.0002685|0|0|0.0002685|gnomAD_NFE|||||||||||||||rs758790416|9.66548e-05|2.64028e-04|0.00000e+00|9.71062e-05|0.00000e+00|0.00000e+00|0.00000e+00|2.64028e-04|0.00000e+00|0.00000e+00 1 69453 . G A 49.81 PASS CSQ=A|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.363G>A|ENSP00000334393.3:p.Lys121%3D|363|363|121|K|aaG/aaA|rs2854682|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||||||||||7.371e-05|0.0002519|0.0001502|0|0|0|5.667e-05|0|8.675e-05|0.0002519|gnomAD_AFR|||||||||||||||rs2854682|4.73394e-04|3.95946e-04|3.95946e-04|1.45829e-04|0.00000e+00|0.00000e+00|0.00000e+00|6.96728e-05|0.00000e+00|8.71764e-05,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000012|open_chromatin_region||||||||||rs2854682|1||||SNV||||||||||||||||||||||||||7.371e-05|0.0002519|0.0001502|0|0|0|5.667e-05|0|8.675e-05|0.0002519|gnomAD_AFR|||||||||||||||rs2854682|4.73394e-04|3.95946e-04|3.95946e-04|1.45829e-04|0.00000e+00|0.00000e+00|0.00000e+00|6.96728e-05|0.00000e+00|8.71764e-05 1 69469 . ACAATT A 305.81 PASS CSQ=-|frameshift_variant|HIGH|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.380_384del|ENSP00000334393.3:p.Thr127AsnfsTer38|380-384|380-384|127-128|TI/X|aCAATT/a||1||1||deletion|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00245&PROSITE_profiles:PS50262||||||||||||||||||||||||||||||HC||SINGLE_EXON|POSITION:0.418300653594771&PHYLOCSF_TOO_SHORT|||rs1350212330|9.20463e-06|8.71536e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|8.71536e-05 1 69486 . C T 3323 PASS CSQ=T|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.396C>T|ENSP00000334393.3:p.Asn132%3D|396|396|132|N|aaC/aaT|rs548369610|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00245&PROSITE_profiles:PS50262|||0.0002|0|0|0.001|0|0|||2.477e-05|0|0|0|0|0|5.737e-05|0|0|0.001|EAS|||||||||||||||rs548369610|1.90042e-05|5.64223e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.64223e-05|0.00000e+00|0.00000e+00 1 69489 . A C 1388.94 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.399A>C|ENSP00000334393.3:p.Ala133%3D|399|399|133|A|gcA/gcC|rs756368346|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00245&PROSITE_profiles:PS50262|||||||||||0.0001428|0|0|0|0|0|0|0|0.000999|0.000999|gnomAD_SAS|||||||||||||||rs756368346|1.15315e-04|1.00384e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.41475e-05|0.00000e+00|1.00384e-03 1 69496 . G A 2206.7 PASS CSQ=A|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.406G>A|ENSP00000334393.3:p.Gly136Ser|406|406|136|G/S|Ggc/Agc|rs150690004|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(0.4)|benign(0.061)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||0.0010|0.003|0.0014|0|0|0|0.00604|0.0002956|0.0006657|0.006109|0.00143|0|0|0|7.305e-05|0|8.709e-05|0.006109|gnomAD_AFR|||||||||||||||rs150690004|6.64393e-04|6.10650e-03|6.10650e-03|1.53709e-03|0.00000e+00|0.00000e+00|0.00000e+00|7.18061e-05|5.26316e-04|8.74967e-05 1 69511 . A G 2.06814e+07 PASS CSQ=G|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.421A>G|ENSP00000334393.3:p.Thr141Ala|421|421|141|T/A|Aca/Gca|rs2691305|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(0.82)|benign(0)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||0.5441|0.8874|0.9506|0.6074|0.9508|0.9779|0.9995|0.9915|0.9728|0.9499|0.9854|0.9995|gnomAD_EAS|||||||||||||||rs2691305|8.77680e-01|9.99439e-01|6.07496e-01|9.51366e-01|9.76661e-01|9.99439e-01|9.91577e-01|9.72624e-01|9.50621e-01|9.85395e-01 1 69552 . G C 773.23 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.462G>C|ENSP00000334393.3:p.Ala154%3D|462|462|154|A|gcG/gcC|rs2531266&COSM2240641|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||||||||||1.263e-05|0|5.096e-05|0.0002009|0|0|0|0|0|0.0002009|gnomAD_ASJ||0&1|0&1|20307285|||||||||||rs2531266|1.66348e-02|4.94854e-05|0.00000e+00|4.94854e-05|1.95236e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 69559 . G A 728.81 PASS CSQ=A|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.469G>A|ENSP00000334393.3:p.Val157Met|469|469|157|V/M|Gtg/Atg|rs754025211|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.02)|possibly_damaging(0.675)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||||||||||9.668e-05|0|0|0|0.0009542|0|0|0|0|0.0009542|gnomAD_EAS|||||||||||||||rs754025211|8.91054e-05|8.94055e-04|0.00000e+00|0.00000e+00|0.00000e+00|8.94055e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 69561 . G T 2457.45 PASS CSQ=T|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.471G>T|ENSP00000334393.3:p.Val157%3D|471|471|157|V|gtG/gtT||1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||||||||||||||||||||||||||||||||||||||||||||| 1 69569 . T C 213.44 PASS CSQ=C|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.479T>C|ENSP00000334393.3:p.Leu160Pro|479|479|160|L/P|cTc/cCc|rs2531267&COSM1599955|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(1)|benign(0)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||0.0002|0.0008|0|0|0|0|||0.0002122|8.548e-05|0.0007621|0.0001898|0.0001785|0|0.0001266|0.0002795|8.276e-05|0.0008|AFR||0&1|0&1||||||||||||rs2531267|1.18409e-02|7.40683e-04|8.06972e-05|7.40683e-04|1.84843e-04|1.67205e-04|0.00000e+00|1.80080e-04|2.50250e-04|8.32224e-05 1 69590 . T A 636.82 PASS CSQ=A|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.500T>A|ENSP00000334393.3:p.Val167Asp|500|500|167|V/D|gTc/gAc|rs141776804|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0)|possibly_damaging(0.589)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||0.0008|0|0.0058|0|0|0|0.0002812|0|0.001955|0|0.01267|0|0|0|0|0.003346|0|0.01267|gnomAD_AMR|||||||||||||||rs141776804|1.81166e-03|1.32065e-02|8.09192e-05|1.32065e-02|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.23769e-03|0.00000e+00 1 69594 . T C 7779.04 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.504T>C|ENSP00000334393.3:p.Asp168%3D|504|504|168|D|gaT/gaC|rs144967600|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||0.0020|0|0|0|0|0.0102|0|0.000323|0.001155|0|0|0|0|0|2.823e-05|0.000558|0.007927|0.0102|SAS|||||||||||||||rs144967600|9.93258e-04|8.05380e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|4.16852e-05|9.95520e-04|8.05380e-03 1 69604 . T C 616.63 PASS CSQ=C|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.514T>C|ENSP00000334393.3:p.Cys172Arg|514|514|172|C/R|Tgt/Cgt||1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0)|probably_damaging(0.995)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Prints_domain:PR00245&PROSITE_profiles:PS50262||||||||||||||||||||||||||||||||||||rs1296836853|4.92102e-06|1.39159e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.39159e-05|0.00000e+00|0.00000e+00 1 69610 . C T 4337.59 PASS CSQ=T|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.520C>T|ENSP00000334393.3:p.Leu174Phe|520|520|174|L/F|Ctt/Ttt|rs376022826&COSM2240643|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(0.11)|possibly_damaging(0.679)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Prints_domain:PR00245&PROSITE_profiles:PS50262|||0.0022|0|0|0.0109|0|0|||0.0009706|0|7.948e-05|0|0.009638|0|0|0|0|0.0109|EAS||0&1|0&1||||||||||||rs376022826|8.90851e-04|9.75691e-03|0.00000e+00|7.72798e-05|0.00000e+00|9.75691e-03|0.00000e+00|0.00000e+00|2.50000e-04|0.00000e+00 1 69634 . T A 1464.25 PASS CSQ=A|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.544T>A|ENSP00000334393.3:p.Cys182Ser|544|544|182|C/S|Tgt/Agt|rs745433879|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0)|probably_damaging(0.987)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Prints_domain:PR00245&PROSITE_profiles:PS50262|||||||||||6.915e-06|0|0|0|0|0|1.603e-05|0|0|1.603e-05|gnomAD_NFE||||||||||||||||||||||||| 1 69640 . G C 360.75 PASS CSQ=C|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.550G>C|ENSP00000334393.3:p.Asp184His|550|550|184|D/H|Gat/Cat|rs769358925|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.01)|possibly_damaging(0.845)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Prints_domain:PR00245&PROSITE_profiles:PS50262|||||||||||0.0002468|0.00262|0.0001984|0|0|0|0|0|5.776e-05|0.00262|gnomAD_AFR|||||||||||||||rs769358925|1.80505e-04|2.50995e-03|2.50995e-03|1.95287e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.79912e-05 1 69678 . T A 231.22 PASS CSQ=A|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.588T>A|ENSP00000334393.3:p.Ser196Arg|588|588|196|S/R|agT/agA||1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0)|probably_damaging(0.992)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||||||||||||||||||||||||||||||||||||||| 1 69690 . T A 289.94 PASS CSQ=A|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.600T>A|ENSP00000334393.3:p.Thr200%3D|600|600|200|T|acT/acA||1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||||||||||||||||||||||||||||||||||||||| 1 69696 . T C 37.01 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.606T>C|ENSP00000334393.3:p.Cys202%3D|606|606|202|C|tgT/tgC||1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||||||||||||||||||||||||||||||||||||||| 1 69713 . T C 498.13 PASS CSQ=C|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.623T>C|ENSP00000334393.3:p.Ile208Thr|623|623|208|I/T|aTc/aCc|rs755278732|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.01)|benign(0.245)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||||3.841e-05|0|0|0|0|0|9.731e-05|0|0|9.731e-05|gnomAD_NFE|||||||||||||||rs755278732|2.85365e-05|9.49532e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|9.49532e-05|0.00000e+00|0.00000e+00 1 69719 . C G 7943.31 PASS CSQ=G|stop_gained|HIGH|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.629C>G|ENSP00000334393.3:p.Ser210Ter|629|629|210|S/*|tCa/tGa||1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262||||||||||||||||||||||||||||||HC||SINGLE_EXON|POSITION:0.685185185185185&PHYLOCSF_TOO_SHORT||||||||||||| 1 69761 . A T 180095 PASS CSQ=T|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.671A>T|ENSP00000334393.3:p.Asp224Val|671|671|224|D/V|gAt/gTt|rs200505207|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.02)|benign(0.229)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&PROSITE_profiles:PS50262|||0.0367|0.0045|0.0418|0.001|0.1034|0.045|0.02136|0.1361|0.09385|0.01198|0.06994|0.1692|0.0001669|0.2223|0.1558|0.1082|0.07704|0.2223|gnomAD_FIN|||||||||||||||rs200505207|1.01568e-01|1.52179e-01|1.20779e-02|7.00815e-02|1.69218e-01|7.83208e-05|2.21441e-01|1.52179e-01|1.03081e-01|7.63772e-02 1 69808 . G C 52.73 PASS CSQ=C|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.718G>C|ENSP00000334393.3:p.Val240Leu|718|718|240|V/L|Gtt/Ctt|rs562438572|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||deleterious(0.01)|probably_damaging(0.983)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||0.0028|0.0098|0.0014|0|0|0|||0.001128|0.006792|0.001127|0|0|0|0|0|0.0001953|0.0098|AFR|||||||||||||||rs562438572|6.23982e-04|6.23167e-03|6.23167e-03|9.29714e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.94780e-04 1 69816 . G C 158.87 PASS CSQ=C|missense_variant|MODERATE|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.726G>C|ENSP00000334393.3:p.Leu242Phe|726|726|242|L/F|ttG/ttC|rs748526036|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||tolerated(0.05)|benign(0.021)|hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&PROSITE_profiles:PS50262|||||||||||5.336e-05|0|0|0|0|0|0.0001677|0|0|0.0001677|gnomAD_NFE|||||||||||||||rs748526036|4.60024e-05|1.48765e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.48765e-04|0.00000e+00|0.00000e+00 1 69897 . T C 21493.6 PASS CSQ=C|synonymous_variant|LOW|OR4F5|ENSG00000186092|Transcript|ENST00000335137|protein_coding|1/1||ENST00000335137.3:c.807T>C|ENSP00000334393.3:p.Ser269%3D|807|807|269|S|tcT/tcC|rs200676709|1||1||SNV|HGNC|14825|YES|||CCDS30547.1|ENSP00000334393|Q8NH21||UPI0000041BC1|||||hmmpanther:PTHR26451&hmmpanther:PTHR26451:SF72&Gene3D:1.20.1070.10&Pfam_domain:PF13853&Superfamily_domains:SSF81321&Transmembrane_helices:TMhelix&Prints_domain:PR00237&PROSITE_profiles:PS50262|||0.6881|0.407|0.6254|0.876|0.7942|0.8098|||0.7165|0.3116|0.6707|0.8132|0.7765|0.8693|0.8442|0.7639|0.8051|0.876|EAS|||||||||||||||rs200676709|6.74863e-01|8.43776e-01|3.07012e-01|6.74863e-01|8.13084e-01|7.79298e-01|8.65169e-01|8.43776e-01|7.93201e-01|8.04920e-01 1 120705 . T C 4309.8 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA||1/3|ENST00000466430.1:n.158+70A>G|||||||rs4117992|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120745 . C T 2554.27 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA||1/3|ENST00000466430.1:n.158+30G>A|||||||rs867615110|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120866 . A T 264.81 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|1/4||ENST00000466430.1:n.67T>A||67||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120871 . C T 18169.1 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|1/4||ENST00000466430.1:n.62G>A||62|||||rs866456737|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120895 . CTTTA C,TTTTA 94555.5 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|1/4||ENST00000466430.1:n.34_37del||34-38||||||1||-1||indel|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,TTTTA|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|1/4||ENST00000466430.1:n.38delinsA||34-38|||||rs866545212|2||-1||indel|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120961 . T C 82329.4 PASS CSQ=C|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|||||||||||1|29|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120969 . T C 375.43 PASS CSQ=C|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|||||||||||1|37|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120983 . C T 164831 PASS CSQ=T|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA||||||||||rs182468771|1|51|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120991 . T C 297.25 PASS CSQ=C|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|||||||||||1|59|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120994 . AAT A 87808.8 PASS CSQ=-|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA||||||||||rs796462195|1|63|-1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 120998 . T G 86.53 PASS CSQ=G|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|||||||||||1|66|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 121009 . C T 8082.65 PASS CSQ=T|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA||||||||||rs1851943|1|77|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 121028 . CTA C 81.23 PASS CSQ=-|upstream_gene_variant|MODIFIER|RP11-34P13.7|ENSG00000238009|Transcript|ENST00000466430|lincRNA|||||||||||1|97|-1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 129077 . G A 84.32 PASS CSQ=A|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1948|1||SNV|HGNC|48835|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 129122 . A G 121.6 PASS CSQ=G|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1903|1||SNV|HGNC|48835|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 129148 . GT GTT,G 343484 PASS CSQ=TT|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1876|1||sequence_alteration|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||2|1876|1||sequence_alteration|HGNC|48835|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 129285 . G A 6740.47 PASS CSQ=A|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs372768449|1|1740|1||SNV|HGNC|48835|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 129301 . T C 36.87 PASS CSQ=C|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1724|1||SNV|HGNC|48835|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 129315 . A G 1616.86 PASS CSQ=G|upstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs375743083|1|1710|1||SNV|HGNC|48835|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 133355 . G T 107.63 PASS CSQ=T|downstream_gene_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||||||||||rs879582929|1|1546|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|1/1||ENST00000442987.3:n.2331G>T||2331|||||rs879582929|1||1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs879582929|1|1786|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs879582929|1|4327|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 133392 . G A 31.55 PASS CSQ=A|downstream_gene_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|||||||||||1|1509|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|1/1||ENST00000442987.3:n.2368G>A||2368||||||1||1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|1749|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|4290|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 133477 . G T 40.05 PASS CSQ=T|downstream_gene_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|||||||||||1|1424|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|1/1||ENST00000442987.3:n.2453G>T||2453||||||1||1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|1664|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|4205|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 133483 . G T 143466 PASS CSQ=T|downstream_gene_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||||||||||rs369820305|1|1418|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|1/1||ENST00000442987.3:n.2459G>T||2459|||||rs369820305|1||1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs369820305|1|1658|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs369820305|1|4199|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 133558 . C T 1041.19 PASS CSQ=T|downstream_gene_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||||||||||rs867188770|1|1343|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|1/1||ENST00000442987.3:n.2534C>T||2534|||||rs867188770|1||1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs867188770|1|1583|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs867188770|1|4124|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135147 . G A 1291.73 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1565C>T||2415||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|311|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4643|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.749C>T||749||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2535|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135151 . G A 2099.5 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1561C>T||2411|||||rs566851375|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0006|0.0008|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs566851375|1|315|1||SNV|HGNC|48835|YES|||||||||||||||0.0006|0.0008|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs566851375|1|4639|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0.0008|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.745C>T||745|||||rs566851375|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0.0008|0|0|0|0.002||||||||||||0.002|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs566851375|1|2531|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0.0008|0|0|0|0.002||||||||||||0.002|SAS||||||||||||||||||||||||| 1 135156 . G A 205.77 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1556C>T||2406||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|320|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4634|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.740C>T||740||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2526|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135162 . G A 542.06 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1550C>T||2400|||||rs538707913|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0010|0.0038|0|0|0|0||||||||||||0.0038|AFR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs538707913|1|326|1||SNV|HGNC|48835|YES|||||||||||||||0.0010|0.0038|0|0|0|0||||||||||||0.0038|AFR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs538707913|1|4628|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0010|0.0038|0|0|0|0||||||||||||0.0038|AFR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.734C>T||734|||||rs538707913|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0010|0.0038|0|0|0|0||||||||||||0.0038|AFR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs538707913|1|2520|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0010|0.0038|0|0|0|0||||||||||||0.0038|AFR||||||||||||||||||||||||| 1 135163 . C T 12557.3 PASS CSQ=T|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1549G>A||2399|||||rs374499151|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0389|0|0.0144|0.0923|0.003|0.091||||||||||||0.0923|EAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs374499151|1|327|1||SNV|HGNC|48835|YES|||||||||||||||0.0389|0|0.0144|0.0923|0.003|0.091||||||||||||0.0923|EAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs374499151|1|4627|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0389|0|0.0144|0.0923|0.003|0.091||||||||||||0.0923|EAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.733G>A||733|||||rs374499151|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0389|0|0.0144|0.0923|0.003|0.091||||||||||||0.0923|EAS|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs374499151|1|2519|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0389|0|0.0144|0.0923|0.003|0.091||||||||||||0.0923|EAS||||||||||||||||||||||||| 1 135172 . C T 977.65 PASS CSQ=T|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1540G>A||2390||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|336|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4618|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.724G>A||724||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2510|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135173 . G A 157.94 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1539C>T||2389|||||rs575342270|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs575342270|1|337|1||SNV|HGNC|48835|YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs575342270|1|4617|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.723C>T||723|||||rs575342270|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs575342270|1|2509|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS||||||||||||||||||||||||| 1 135178 . C T 1391.25 PASS CSQ=T|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1534G>A||2384|||||rs868859840|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs868859840|1|342|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs868859840|1|4612|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.718G>A||718|||||rs868859840|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs868859840|1|2504|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135187 . GC G 35.93 PASS CSQ=-|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1524del||2374||||||1||-1||deletion|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|352|1||deletion|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4602|-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.708del||708||||||1||-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2494|-1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135193 . G A 184.35 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1519C>T||2369||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|357|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4597|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.703C>T||703||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2489|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135195 . A G 24030.5 PASS CSQ=G|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1517T>C||2367|||||rs554762511|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0036|0.0008|0.0029|0|0.0149|0||||||||||||0.0149|EUR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs554762511|1|359|1||SNV|HGNC|48835|YES|||||||||||||||0.0036|0.0008|0.0029|0|0.0149|0||||||||||||0.0149|EUR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs554762511|1|4595|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0036|0.0008|0.0029|0|0.0149|0||||||||||||0.0149|EUR|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.701T>C||701|||||rs554762511|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0036|0.0008|0.0029|0|0.0149|0||||||||||||0.0149|EUR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs554762511|1|2487|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0036|0.0008|0.0029|0|0.0149|0||||||||||||0.0149|EUR||||||||||||||||||||||||| 1 135196 . G A 145.95 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1516C>T||2366||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|360|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4594|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.700C>T||700||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2486|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135203 . G A 137701 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1509C>T||2359|||||rs147502335|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0280|0.0076|0.0086|0|0.0527|0.0726||||||||||||0.0726|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs147502335|1|367|1||SNV|HGNC|48835|YES|||||||||||||||0.0280|0.0076|0.0086|0|0.0527|0.0726||||||||||||0.0726|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs147502335|1|4587|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0280|0.0076|0.0086|0|0.0527|0.0726||||||||||||0.0726|SAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.693C>T||693|||||rs147502335|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0280|0.0076|0.0086|0|0.0527|0.0726||||||||||||0.0726|SAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs147502335|1|2479|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0280|0.0076|0.0086|0|0.0527|0.0726||||||||||||0.0726|SAS||||||||||||||||||||||||| 1 135215 . G A 692.62 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1497C>T||2347||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|379|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4575|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.681C>T||681||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2467|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135224 . G A 75.98 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1488C>T||2338||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|388|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4566|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.672C>T||672||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2458|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135232 . C T 6306.06 PASS CSQ=T|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1480G>A||2330||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|396|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4558|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.664G>A||664||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2450|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135265 . T C 98.15 PASS CSQ=C|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1447A>G||2297|||||rs530645387|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0044|0.0166|0|0|0|0||||||||||||0.0166|AFR|||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs530645387|1|429|1||SNV|HGNC|48835|YES|||||||||||||||0.0044|0.0166|0|0|0|0||||||||||||0.0166|AFR|||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs530645387|1|4525|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0044|0.0166|0|0|0|0||||||||||||0.0166|AFR|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.631A>G||631|||||rs530645387|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0044|0.0166|0|0|0|0||||||||||||0.0166|AFR|||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs530645387|1|2417|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0044|0.0166|0|0|0|0||||||||||||0.0166|AFR||||||||||||||||||||||||| 1 135297 . C T 292.28 PASS CSQ=T|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|2/2||ENST00000423372.3:c.*1415G>A||2265||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|461|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|4493|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|1/1||ENST00000494149.2:n.599G>A||599||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|2385|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 135982 . A G 3509.37 PASS CSQ=G|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-180T>C|||||||rs2461551|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||0.6399|0.9553|0.9851|0.9851|0.9744||||||||||||0.9851|EAS&EUR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs2461551|1|1146|1||SNV|HGNC|48835|YES||||||||||||||||0.6399|0.9553|0.9851|0.9851|0.9744||||||||||||0.9851|EAS&EUR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs2461551|1|3808|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||0.6399|0.9553|0.9851|0.9851|0.9744||||||||||||0.9851|EAS&EUR|||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs2461551|1|87|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||0.6399|0.9553|0.9851|0.9851|0.9744||||||||||||0.9851|EAS&EUR|||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs2461551|1|1700|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||0.6399|0.9553|0.9851|0.9851|0.9744||||||||||||0.9851|EAS&EUR||||||||||||||||||||||||| 1 136041 . C A 72.79 PASS CSQ=A|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-239G>T||||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1205|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|3749|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|146|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|1641|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136048 . C T 180580 PASS CSQ=T|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-246G>A|||||||rs77222689|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs77222689|1|1212|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs77222689|1|3742|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs77222689|1|153|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs77222689|1|1634|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136060 . G A 114.3 PASS CSQ=A|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-258C>T||||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1224|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|3730|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|165|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|1622|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136068 . C T 44648.6 PASS CSQ=T|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-266G>A||||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1232|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|3722|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|173|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|1614|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136073 . C A 30.75 PASS CSQ=A|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-271G>T||||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1237|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|3717|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|178|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|1609|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136082 . G A 32.1 PASS CSQ=A|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-280C>T||||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1246|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|3708|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|187|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|1600|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136113 . C T 120511 PASS CSQ=T|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-311G>A|||||||rs546872994|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512||||||||0.0100|0.0015|0.0144|0|0.0278|0.0102||||||||||||0.0278|EUR|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs546872994|1|1277|1||SNV|HGNC|48835|YES|||||||||||||||0.0100|0.0015|0.0144|0|0.0278|0.0102||||||||||||0.0278|EUR|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs546872994|1|3677|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0100|0.0015|0.0144|0|0.0278|0.0102||||||||||||0.0278|EUR|||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs546872994|1|218|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0100|0.0015|0.0144|0|0.0278|0.0102||||||||||||0.0278|EUR|||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs546872994|1|1569|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0100|0.0015|0.0144|0|0.0278|0.0102||||||||||||0.0278|EUR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000018|TF_binding_site||||||||||rs546872994|1||||SNV||||||||||||||||||0.0100|0.0015|0.0144|0|0.0278|0.0102||||||||||||0.0278|EUR||||||||||||||||||||||||| 1 136124 . G A 99.63 PASS CSQ=A|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-322C>T|||||||rs374467255|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs374467255|1|1288|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs374467255|1|3666|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs374467255|1|229|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs374467255|1|1558|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000018|TF_binding_site||||||||||rs374467255|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 136210 . G A 129.71 PASS CSQ=A|intron_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding||1/1|ENST00000423372.3:c.*910-408C>T||||||||1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene|||||||||||1|1374|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense|||||||||||1|3580|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene|||||||||||1|315|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|||||||||||1|1472|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000018|TF_binding_site|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 137622 . G A 240.87 PASS CSQ=A|splice_region_variant&3_prime_UTR_variant|LOW|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|1/2||ENST00000423372.3:c.*908C>T||1758|||||rs376555721|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs376555721|1|2786|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.13|ENSG00000241860|Transcript|ENST00000484859|antisense||||||||||rs376555721|1|3852|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs376555721|1|2168|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs376555721|1|1727|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene||||||||||rs376555721|1|60|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000018|TF_binding_site||||||||||rs376555721|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 137825 . G A 119793 PASS CSQ=A|3_prime_UTR_variant|MODIFIER|AL627309.1|ENSG00000237683|Transcript|ENST00000423372|protein_coding|1/2||ENST00000423372.3:c.*705C>T||1555|||||rs147252685|1||-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000473460||R4GN28&B7Z7W4|UPI0002C88512|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|CICP27|ENSG00000233750|Transcript|ENST00000442987|processed_pseudogene||||||||||rs147252685|1|2989|1||SNV|HGNC|48835|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.13|ENSG00000241860|Transcript|ENST00000484859|antisense||||||||||rs147252685|1|3649|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.13|ENSG00000241860|Transcript|ENST00000490997|antisense||||||||||rs147252685|1|4983|-1||SNV|Clone_based_vega_gene||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|RP11-34P13.14|ENSG00000239906|Transcript|ENST00000493797|antisense||||||||||rs147252685|1|1965|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-34P13.15|ENSG00000268903|Transcript|ENST00000494149|processed_pseudogene||||||||||rs147252685|1|1930|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-34P13.16|ENSG00000269981|Transcript|ENST00000595919|processed_pseudogene|1/1||ENST00000595919.1:n.141C>T||141|||||rs147252685|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267027 . A G 159.11 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||1/3|ENST00000424587.2:n.158+69T>C||||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267069 . G A 2671.44 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||1/3|ENST00000424587.2:n.158+27C>T|||||||rs867044312|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267083 . G A 64.26 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||1/3|ENST00000424587.2:n.158+13C>T||||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267099 . C G 192.81 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.155G>C||155||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267132 . T C 3289.74 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.122A>G||122|||||rs550489103|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0.0008|0.0014|0|0.001|0||||||||||||0.0014|AMR||||||||||||||||||||||||| 1 267147 . G A 142.23 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.107C>T||107||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267154 . C T 19978.8 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.100G>A||100||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267216 . C T 187.14 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.38G>A||38||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267220 . A C 213.29 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.34T>G||34|||||rs1005512472|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267226 . C A 66.52 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.28G>T||28|||||rs1016770593|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267227 . TTAA T 101119 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.24_26del||24-26|||||rs374780253|1||-1||deletion|Clone_based_vega_gene||YES|||||||||||||||0.0399|0.0545|0.0115|0.0407|0.0099|0.0706||||||||||||0.0706|SAS||||||||||||||||||||||||| 1 267229 . A *,C 156630 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|1/4||ENST00000424587.2:n.25T>G||25||||||2||-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267268 . A C 1112.11 PASS CSQ=C|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||||||||||rs955529495|1|15|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267276 . A G 1380.44 PASS CSQ=G|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||1|23|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267282 . T C 690.8 PASS CSQ=C|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||||||||||rs200984748|1|29|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0.001|0|0||||||||||||0.001|EAS||||||||||||||||||||||||| 1 267289 . T TTA 2809.66 PASS CSQ=TA|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||1|36|-1||insertion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267293 . ATATC A 403.11 PASS CSQ=-|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||1|41|-1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267294 . TATCTATTATATATAATATTATATATCTATTATATATTATATATTGTATATCTATTACATATATAATATTATATATGTATTATATATATTATATATTA T,* 47259.4 PASS CSQ=-|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||1|42|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267295 . A C,* 64218.9 PASS CSQ=C|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||||||||||rs528900950|1|42|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||0.0008|0.0008|0.0014|0|0.001|0.001||||||||||||0.0014|AMR||||||||||||||||||||||||| 1 267300 . T *,TTA 53059.2 PASS CSQ=TA|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||||||||||rs924631806|2|47|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267303 . T *,C 62423.3 PASS CSQ=C|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|50|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267305 . TATA *,T,CATA 144971 PASS CSQ=T|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|52|-1||sequence_alteration|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,CATA|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||3|52|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267309 . ATAT *,TTAT 145363 PASS CSQ=TTAT|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|56|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267310 . T *,A 63099.9 PASS CSQ=A|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|57|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267316 . ATATC *,A 77789.8 PASS CSQ=-|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|64|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267319 . T *,C 77970.5 PASS CSQ=C|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|66|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267324 . T *,G,C 185470 PASS CSQ=G|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||||||||||rs541271246|2|71|-1||sequence_alteration|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||3|71|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267331 . T *,A 98694.5 PASS CSQ=A|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|78|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267355 . TATA T,* 182207 PASS CSQ=-|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA||||||||||rs756558238|1|103|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 267359 . ATAT *,A 146369 PASS CSQ=-|upstream_gene_variant|MODIFIER|AP006222.2|ENSG00000228463|Transcript|ENST00000424587|lincRNA|||||||||||2|107|-1||sequence_alteration|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 647265 . C T 391.71 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP5-857K21.4|ENSG00000230021|Transcript|ENST00000414688|lincRNA|2/2||ENST00000414688.1:n.207G>A||207|||||rs866330608|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344286|TF_binding_site||||||||||rs866330608|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 647380 . T C 1741.48 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|RP5-857K21.4|ENSG00000230021|Transcript|ENST00000414688|lincRNA||1/1|ENST00000414688.1:n.170-78A>G||||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 647398 . T C 680.51 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|RP5-857K21.4|ENSG00000230021|Transcript|ENST00000414688|lincRNA||1/1|ENST00000414688.1:n.170-96A>G||||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 662029 . G A 14832.6 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene|||||||||||1|1746|1||SNV|HGNC|37742|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene|2/2||ENST00000506640.1:n.818C>T||818||||||1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 662414 . C T 796.79 PASS CSQ=T|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs371628865|1|2131|1||SNV|HGNC|37742|YES|||||||||||||||0.1745|0.2511|0.0749|0.1776|0.1193|0.1953||||||||||||0.2511|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.475-42G>A|||||||rs371628865|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.1745|0.2511|0.0749|0.1776|0.1193|0.1953||||||||||||0.2511|AFR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs371628865|1||||SNV||||||||||||||||||0.1745|0.2511|0.0749|0.1776|0.1193|0.1953||||||||||||0.2511|AFR||||||||||||||||||||||||| 1 662531 . G A 382.5 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs572257073|1|2248|1||SNV|HGNC|37742|YES|||||||||||||||0.0010|0|0|0|0.005|0||||||||||||0.005|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.475-159C>T|||||||rs572257073|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0010|0|0|0|0.005|0||||||||||||0.005|EUR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs572257073|1||||SNV||||||||||||||||||0.0010|0|0|0|0.005|0||||||||||||0.005|EUR||||||||||||||||||||||||| 1 662613 . G A 555.37 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs151190501|1|2330|1||SNV|HGNC|37742|YES|||||||||||||||0.0058|0|0.0058|0|0.0199|0.0051||||||||||||0.0199|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.475-241C>T|||||||rs151190501|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0058|0|0.0058|0|0.0199|0.0051||||||||||||0.0199|EUR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs151190501|1||||SNV||||||||||||||||||0.0058|0|0.0058|0|0.0199|0.0051||||||||||||0.0199|EUR||||||||||||||||||||||||| 1 662622 . G A 11370 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs61769339|1|2339|1||SNV|HGNC|37742|YES|||||||||||||||0.1476|0.2405|0.0504|0.1042|0.1103|0.1738||||||||||||0.2405|AFR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.475-250C>T|||||||rs61769339|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.1476|0.2405|0.0504|0.1042|0.1103|0.1738||||||||||||0.2405|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs61769339|1||||SNV||||||||||||||||||0.1476|0.2405|0.0504|0.1042|0.1103|0.1738||||||||||||0.2405|AFR||||||||||||||||||||||||| 1 662623 . G A 106.62 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs563408038|1|2340|1||SNV|HGNC|37742|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.475-251C>T|||||||rs563408038|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs563408038|1||||SNV||||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 662843 . G A 51.79 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene|||||||||||1|2560|1||SNV|HGNC|37742|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.474+211C>T||||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 662857 . G A 4836.98 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs377354243|1|2574|1||SNV|HGNC|37742|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene||1/1|ENST00000506640.1:n.474+197C>T|||||||rs377354243|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs377354243|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 663083 . C A 30.14 PASS CSQ=A|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene|||||||||||1|2800|1||SNV|HGNC|37742|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene|1/2||ENST00000506640.1:n.445G>T||445||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 663097 . G C 182097 PASS CSQ=C|downstream_gene_variant|MODIFIER|CICP3|ENSG00000229376|Transcript|ENST00000440782|processed_pseudogene||||||||||rs61769340|1|2814|1||SNV|HGNC|37742|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.1|ENSG00000224956|Transcript|ENST00000506640|unprocessed_pseudogene|1/2||ENST00000506640.1:n.431C>G||431|||||rs61769340|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000073|TF_binding_site||||||||||rs61769340|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717379 . CCA C 4704.19 PASS CSQ=-|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3374|-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3799|1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717396 . T C 1906.9 PASS CSQ=C|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3390|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3784|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717432 . A T 2469.93 PASS CSQ=T|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3426|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3748|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717474 . C T 26289.1 PASS CSQ=T|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA||||||||||rs141784362|1|3468|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0250|0.084|0.013|0|0.005|0||||||||||||0.084|AFR|||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA||||||||||rs141784362|1|3706|1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0250|0.084|0.013|0|0.005|0||||||||||||0.084|AFR||||||||||||||||||||||||| 1 717481 . A G 404.68 PASS CSQ=G|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3475|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3699|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717485 . C A 212032 PASS CSQ=A|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA||||||||||rs12184279|1|3479|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||20637081|||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA||||||||||rs12184279|1|3695|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||20637081||||||||||||||||||||| 1 717486 . G A,T 32659.3 PASS CSQ=A|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA||||||||||rs140304290|1|3480|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0012|0|0|0.006|0|0||||||||||||0.006|EAS|||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||2|3480|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA||||||||||rs140304290|1|3694|1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0012|0|0|0.006|0|0||||||||||||0.006|EAS|||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||2|3694|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717519 . A G 855.96 PASS CSQ=G|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3513|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3661|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717534 . C T 247.03 PASS CSQ=T|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3528|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3646|1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 717574 . C CA 511.84 PASS CSQ=A|upstream_gene_variant|MODIFIER|RP11-206L10.2|ENSG00000228327|Transcript|ENST00000428504|lincRNA|||||||||||1|3568|-1||insertion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|||||||||||1|3605|1||insertion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721256 . G C 653.75 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.77G>C||77||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721288 . G A 1394.73 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.109G>A||109||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721290 . G C 409165 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.111G>C||111|||||rs12565286|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0371|0.028|0.0288|0.0377|0.0457|0.046||||||||||||0.046|SAS||||||||||||||||||||||||| 1 721302 . G A 142.33 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.123G>A||123|||||rs530197786|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0004|0|0|0|0|0.002||||||||||||0.002|SAS||||||||||||||||||||||||| 1 721303 . G C 547.68 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.124G>C||124||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721311 . A G 82.45 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.132A>G||132||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721323 . A G 9640.9 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.144A>G||144|||||rs753948954|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721332 . T C 111.19 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.153T>C||153|||||rs867441942|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721361 . G A 685.35 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.182G>A||182||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1164222178|4.20286e-05|1.78571e-04|1.78571e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 721371 . G A 1818.96 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.192G>A||192|||||rs539194939|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0012|0.0045|0|0|0|0|||0.0005772|0.006647|0.0002279|0|0|0|0.0001235|0.0004596|0.0001025|0.006647|gnomAD_AFR|||||||||||||||rs539194939|4.16800e-04|7.05467e-03|7.05467e-03|2.25632e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.14273e-04|3.76223e-04|1.02354e-04 1 721409 . C G 489.3 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.230C>G||230||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1395460388|2.07569e-05|1.39795e-04|0.00000e+00|1.39795e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 721426 . T C 3558.22 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.247T>C||247||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1319242139|1.38278e-05|3.79449e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.79449e-05|0.00000e+00|0.00000e+00 1 721439 . T C 429 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.260T>C||260|||||rs538812237|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721450 . G A 142327 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.271G>A||271||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs2977675|1.95088e-02|2.30963e-02|1.31497e-02|6.96983e-03|1.59728e-02|2.30963e-02|3.66999e-03|1.40142e-02|2.00803e-02|1.01304e-02 1 721462 . C A 118.02 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.283C>A||283||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721478 . C G 107 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.299C>G||299||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721538 . A C 23812.5 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.359A>C||359|||||rs569523401|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0004|0|0|0|0.002|0|||0.0006955|0.0004797|0.0009291|0.0001242|0|0|0.001228|0.0008183|0|0.002|EUR|||||||||||||||rs569523401|6.64299e-04|1.18964e-03|4.60264e-04|9.03342e-04|1.20569e-04|0.00000e+00|0.00000e+00|1.18964e-03|9.56023e-04|0.00000e+00 1 721540 . G C 1324 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.361G>C||361||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1433663108|6.99242e-06|1.85818e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.85818e-05|0.00000e+00|0.00000e+00 1 721548 . C T 388 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.369C>T||369||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721549 . T G 2475.68 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.370T>G||370||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1341803062|2.09231e-05|5.55782e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.55782e-05|0.00000e+00|0.00000e+00 1 721554 . G A 1288.23 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.375G>A||375||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721566 . T C 1167.23 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.387T>C||387|||||rs745581508|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||0.0001054|0.0001572|0|0|0|0.00115|9.695e-05|0|0|0.00115|gnomAD_FIN|||||||||||||||rs745581508|1.04232e-04|1.50557e-04|1.50557e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.14613e-03|1.10873e-04|0.00000e+00|0.00000e+00 1 721569 . T C 708.56 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.390T>C||390||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721575 . T C 1634.23 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.396T>C||396||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1210396658|3.46798e-05|4.75737e-04|0.00000e+00|0.00000e+00|0.00000e+00|4.75737e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 721576 . G T 559 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.397G>T||397||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1286920999|2.08027e-05|2.85442e-04|0.00000e+00|0.00000e+00|0.00000e+00|2.85442e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 721642 . T A 229 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.463T>A||463||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1287738902|7.02385e-06|1.87238e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.87238e-05|0.00000e+00|0.00000e+00 1 721645 . G C 7781.28 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.466G>C||466|||||rs755523396|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||0.0003635|0|0|0|0|0|5.883e-05|0|0.001995|0.001995|gnomAD_SAS|||||||||||||||rs755523396|3.44483e-04|2.00071e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|7.49148e-05|0.00000e+00|2.00071e-03 1 721668 . C T 991.31 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.489C>T||489|||||rs568198122|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||7.713e-06|0|0|0|0|0|1.986e-05|0|0|1.986e-05|gnomAD_NFE|||||||||||||||rs568198122|7.09713e-06|1.89523e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.89523e-05|0.00000e+00|0.00000e+00 1 721682 . A C 718.04 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.503A>C||503||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721694 . A G 39550.8 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.515A>G||515|||||rs538190743|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0010|0|0|0|0.002|0.0031|||0.002619|0.0001623|0.000932|0.005251|0.0001013|0|0.001185|0.0008292|0.00956|0.00956|gnomAD_SAS|||||||||||||||rs538190743|2.49151e-03|9.57992e-03|1.55860e-04|9.49785e-04|5.33851e-03|9.56572e-05|0.00000e+00|1.22586e-03|7.27096e-04|9.57992e-03 1 721699 . C A 322.04 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.520C>A||520||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721705 . A G 48319.8 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.526A>G||526|||||rs151072073|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0228|0.0832|0.0043|0|0.001|0|||0.003967|0.06786|0.003005|0|0|0|0.0002371|0.003311|0.0002238|0.0832|AFR|||||||||||||||rs151072073|3.85415e-03|6.69476e-02|6.69476e-02|2.96834e-03|0.00000e+00|0.00000e+00|0.00000e+00|2.64061e-04|2.42014e-03|1.79420e-04 1 721707 . C A 1782.34 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.528C>A||528|||||rs774747373|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||7.653e-06|0|0|0|0|0|0|0|4.469e-05|4.469e-05|gnomAD_SAS|||||||||||||||rs774747373|7.07074e-06|4.47868e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|4.47868e-05 1 721708 . T G 1693.8 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.529T>G||529||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1215451830|4.24142e-05|5.65739e-05|0.00000e+00|4.11794e-05|0.00000e+00|0.00000e+00|0.00000e+00|5.65739e-05|0.00000e+00|0.00000e+00 1 721722 . T A 485.33 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.543T>A||543||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721724 . A AT 9571.95 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.549dup||545-546|||||rs371583549|1||1||insertion|Clone_based_vega_gene||YES||||||||||||||4|0.0080|0|0|0.0377|0.001|0.001|||0.002651|0.0003244|0|0|0.0285|0.00335|1.979e-05|0.002208|0.001561|0.0377|EAS|||||||||||||||rs371583549|2.65631e-03|2.84365e-02|3.11818e-04|0.00000e+00|0.00000e+00|2.84365e-02|3.33969e-03|1.88872e-05|2.65957e-03|1.47545e-03 1 721735 . T A 1196.41 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.556T>A||556|||||rs573527598|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0.0008|0|0|0|0|||5.365e-05|0.0009724|0|0|0|0|0|0.0002761|0|0.0009724|gnomAD_AFR|||||||||||||||rs573527598|3.53757e-05|7.79059e-04|7.79059e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 721748 . T G 1053.32 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.569T>G||569|||||rs748499585|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||0.0001392|0|0.0001269|0.001501|0|0|5.986e-05|0|0|0.001501|gnomAD_ASJ|||||||||||||||rs748499585|1.28249e-04|1.23579e-04|0.00000e+00|1.23579e-04|1.45843e-03|0.00000e+00|0.00000e+00|5.70885e-05|0.00000e+00|0.00000e+00 1 721750 . T C 153.38 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.571T>C||571||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721757 . T A 1.07952e+06 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.578T>A||578|||||rs189147642|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0282|0.0265|0.0288|0|0.0437|0.0429|||0.03968|0.02722|0.02321|0.09774|0.0005151|0.01533|0.04526|0.05135|0.04853|0.09774|gnomAD_ASJ|||||||||||||||rs189147642|3.90077e-02|4.86324e-02|2.72471e-02|2.32019e-02|9.86210e-02|4.86003e-04|1.60508e-02|4.55507e-02|5.37475e-02|4.86324e-02 1 721772 . G T 392.41 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.593G>T||593||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721783 . C T 184.84 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.604C>T||604||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721788 . T C 4059.68 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.609T>C||609|||||rs572605413|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0|0.001|||0.0004881|0|8.872e-05|0|0|0|0.0001046|0.0008741|0.002369|0.002369|gnomAD_SAS|||||||||||||||rs572605413|4.84370e-04|2.32448e-03|0.00000e+00|8.66701e-05|0.00000e+00|0.00000e+00|0.00000e+00|5.95782e-05|1.54719e-03|2.32448e-03 1 721798 . G A 597.03 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.619G>A||619||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721806 . T C 326.2 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.627T>C||627|||||rs760820711|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||2.737e-05|0|0|0|0|0|0|0|0.0001645|0.0001645|gnomAD_SAS|||||||||||||||rs760820711|2.18398e-05|1.64636e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.64636e-04 1 721836 . C A 199.2 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.657C>A||657||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1467945036|2.92094e-05|1.84004e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.32656e-05|0.00000e+00|1.84004e-04 1 721847 . CA C 271.3 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.671del||669|||||rs780333268|1||1||deletion|Clone_based_vega_gene||YES||||||||||||||2|||||||||7.826e-05|0|0|0|0|0|0|0|0.0004898|0.0004898|gnomAD_SAS|||||||||||||||rs780333268|6.56675e-05|4.89656e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|4.89656e-04 1 721867 . T C 662.27 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.688T>C||688|||||rs926783010|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||4.856e-05|0|0|0|0|0|0.0001214|0|0|0.0001214|gnomAD_NFE|||||||||||||||rs926783010|4.36142e-05|9.13743e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|9.13743e-05|3.02115e-04|0.00000e+00 1 721873 . C T 1427.21 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.694C>T||694|||||rs776940726|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||0.0001154|0|0|0|0|0|0|0|0.0007148|0.0007148|gnomAD_SAS|||||||||||||||rs776940726|1.01583e-04|7.14456e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|7.14456e-04 1 721884 . A C 296.07 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.705A>C||705|||||rs991179854|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||9.055e-06|0|0|0|0|0|2.258e-05|0|0|2.258e-05|gnomAD_NFE|||||||||||||||rs991179854|7.20877e-06|2.13657e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.13657e-05|0.00000e+00|0.00000e+00 1 721891 . G A 296.06 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.712G>A||712|||||rs544802733|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0.0008|0|0|0|0|||2.675e-05|0.0001712|5.165e-05|0|0|0|2.229e-05|0|0|0.0008|AFR|||||||||||||||rs544802733|4.30515e-05|1.64366e-04|1.64366e-04|1.01204e-04|0.00000e+00|0.00000e+00|0.00000e+00|2.11015e-05|0.00000e+00|0.00000e+00 1 721905 . C T 119.94 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.726C>T||726|||||rs564976404|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0|0.001|||4.326e-05|0|0|0|0|0|0|0|0.0002651|0.001|SAS|||||||||||||||rs564976404|4.27028e-05|2.65252e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.65252e-04 1 721915 . T C 1211.02 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.736T>C||736||||||1||1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||rs1291460017|2.12757e-05|3.27869e-04|3.27869e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 721945 . T C 303.93 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.766T>C||766||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721948 . T G 820 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.769T>G||769||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721964 . T G 89.95 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.785T>G||785||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721977 . C T 89.57 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.798C>T||798||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721984 . TATC T 4181.4 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.808_810del||806-808||||||1||1||deletion|Clone_based_vega_gene||YES||||||||||||||2|||||||||||||||||||||||||||||||||||||||||||| 1 721994 . A G 30.12 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.815A>G||815||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 721996 . G A 977.5 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.817G>A||817|||||rs575481072|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0020|0.0076|0|0|0|0||||||||||||0.0076|AFR||||||||||||||||||||||||| 1 722025 . T A,C 2291.33 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.846T>A||846|||||rs547856006|1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0004|0|0|0|0.001|0.001||||||||||||0.001|EUR&SAS|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.846T>C||846||||||2||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 722032 . C T 40.43 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.9|ENSG00000237491|Transcript|ENST00000591702|lincRNA|1/1||ENST00000591702.1:n.853C>T||853||||||1||1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 741163 . G A 67.26 PASS CSQ=A|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs543219841|1|4326|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||3/3|ENST00000447500.1:n.238+16C>T|||||||rs543219841|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS|||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|AL669831.1|ENSG00000269831|Transcript|ENST00000599533|protein_coding||||||||||rs543219841|1|2026|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000468859||M0QX24|UPI00015E0AF0||||||||0.0006|0|0|0|0|0.0031||||||||||||0.0031|SAS||||||||||||||||||||||||| 1 741181 . T C 158.83 PASS CSQ=C|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs556976003|1|4308|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0024|0.0091|0|0|0|0||||||||||||0.0091|AFR|||||||||||||||||||||||||,C|splice_region_variant&non_coding_transcript_exon_variant|LOW|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|3/4||ENST00000447500.1:n.236A>G||236|||||rs556976003|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0024|0.0091|0|0|0|0||||||||||||0.0091|AFR|||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|AL669831.1|ENSG00000269831|Transcript|ENST00000599533|protein_coding||||||||||rs556976003|1|2044|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000468859||M0QX24|UPI00015E0AF0||||||||0.0024|0.0091|0|0|0|0||||||||||||0.0091|AFR||||||||||||||||||||||||| 1 741235 . G A 13511.6 PASS CSQ=A|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs200926299|1|4254|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0012|0|0|0|0.006|0||||||||||||0.006|EUR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|3/4||ENST00000447500.1:n.182C>T||182|||||rs200926299|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0012|0|0|0|0.006|0||||||||||||0.006|EUR|||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|AL669831.1|ENSG00000269831|Transcript|ENST00000599533|protein_coding||||||||||rs200926299|1|2098|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000468859||M0QX24|UPI00015E0AF0||||||||0.0012|0|0|0|0.006|0||||||||||||0.006|EUR||||||||||||||||||||||||| 1 741260 . A G 191.75 PASS CSQ=G|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs559669593|1|4229|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0020|0.0068|0.0014|0|0|0||||||||||||0.0068|AFR|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|3/4||ENST00000447500.1:n.157T>C||157|||||rs559669593|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0020|0.0068|0.0014|0|0|0||||||||||||0.0068|AFR|||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|AL669831.1|ENSG00000269831|Transcript|ENST00000599533|protein_coding||||||||||rs559669593|1|2123|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000468859||M0QX24|UPI00015E0AF0||||||||0.0020|0.0068|0.0014|0|0|0||||||||||||0.0068|AFR||||||||||||||||||||||||| 1 741267 . T C 24672.5 PASS CSQ=C|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs80183632|1|4222|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||0.0091|0.0648|0.1726|0.002|0.0276||||||||||||0.1726|EAS|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|3/4||ENST00000447500.1:n.150A>G||150|||||rs80183632|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||0.0091|0.0648|0.1726|0.002|0.0276||||||||||||0.1726|EAS|||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|AL669831.1|ENSG00000269831|Transcript|ENST00000599533|protein_coding||||||||||rs80183632|1|2130|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000468859||M0QX24|UPI00015E0AF0|||||||||0.0091|0.0648|0.1726|0.002|0.0276||||||||||||0.1726|EAS||||||||||||||||||||||||| 1 741286 . CAG C 4534.64 PASS CSQ=-|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|4201|-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||2/3|ENST00000447500.1:n.146-17_146-16del||||||||1||-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|upstream_gene_variant|MODIFIER|AL669831.1|ENSG00000269831|Transcript|ENST00000599533|protein_coding|||||||||||1|2150|-1||deletion|Clone_based_ensembl_gene||YES||||ENSP00000468859||M0QX24|UPI00015E0AF0||||||||||||||||||||||||||||||||||||||||||||||||||| 1 745347 . T C 56.66 PASS CSQ=C|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs373594198|1|142|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||1/3|ENST00000447500.1:n.95+100A>G|||||||rs373594198|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 745370 . TA T 8641.83 PASS CSQ=-|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs146246821|1|118|-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||1/3|ENST00000447500.1:n.95+76del|||||||rs146246821|1||-1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 745425 . AAATT A 251.88 PASS CSQ=-|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|60|-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||1/3|ENST00000447500.1:n.95+18_95+21del||||||||1||-1||deletion|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 745439 . G A 34303.8 PASS CSQ=A|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs576986186|1|50|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,A|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||1/3|ENST00000447500.1:n.95+8C>T|||||||rs576986186|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 745477 . C T 17109.4 PASS CSQ=T|downstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs546292184|1|12|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|1/4||ENST00000447500.1:n.65G>A||65|||||rs546292184|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 745573 . T G 276.91 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.341-23A>C||||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|||||||||||1|32|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 745620 . A G 166.67 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.341-70T>C||||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript|||||||||||1|79|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 745642 . AC A 35881.9 PASS CSQ=-|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.341-93del|||||||rs200097270|1||-1||deletion|Clone_based_vega_gene||YES|||||||||||||||0.0270|0.0234|0.0288|0|0.0417|0.0429||||||||||||0.0429|SAS|||||||||||||||||||||||||,-|upstream_gene_variant|MODIFIER|RP11-206L10.8|ENSG00000230092|Transcript|ENST00000447500|processed_transcript||||||||||rs200097270|1|102|-1||deletion|Clone_based_vega_gene||YES|||||||||||||||0.0270|0.0234|0.0288|0|0.0417|0.0429||||||||||||0.0429|SAS||||||||||||||||||||||||| 1 752737 . G C 188.28 PASS CSQ=C|upstream_gene_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA||||||||||rs560420638|1|14|1||SNV|HGNC|32236|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.340+16C>G|||||||rs560420638|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs560420638|1||||SNV||||||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 752745 . C T 183.64 PASS CSQ=T|upstream_gene_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|||||||||||1|6|1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.340+8G>A||||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752748 . G A 3405.74 PASS CSQ=A|upstream_gene_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA||||||||||rs868734960|1|3|1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|splice_region_variant&intron_variant&non_coding_transcript_variant|LOW|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.340+5C>T|||||||rs868734960|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs868734960|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752752 . C T 576.48 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.2C>T||2|||||rs143872709|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0024|0.0091|0|0|0|0||||||||||||0.0091|AFR|||||||||||||||||||||||||,T|splice_donor_variant&non_coding_transcript_variant|HIGH|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||1/1|ENST00000435300.1:n.340+1G>A|||||||rs143872709|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0024|0.0091|0|0|0|0||||||||||||0.0091|AFR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs143872709|1||||SNV||||||||||||||||||0.0024|0.0091|0|0|0|0||||||||||||0.0091|AFR||||||||||||||||||||||||| 1 752770 . T C 110.42 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.20T>C||20||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.323A>G||323||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752796 . C T 248163 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.46C>T||46|||||rs148649543|1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.297G>A||297|||||rs148649543|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs148649543|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752802 . G A 130.02 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.52G>A||52||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.291C>T||291||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752809 . G A 138.95 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.59G>A||59||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.284C>T||284||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752841 . C CG 140.36 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.92dup||91-92||||||1||1||insertion|HGNC|32236|YES||||||||||||||1||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.251dup||251-252||||||1||-1||insertion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||insertion||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752872 . G C 61.83 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.122G>C||122||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.221C>G||221||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752873 . G T 61.96 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.123G>T||123||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.220C>A||220||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752894 . T C 1.70963e+06 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.144T>C||144|||||rs3131971|1||1||SNV|HGNC|32236|YES|||||||||||||||0.7532|0.5129|0.8127|0.8839|0.8419|0.8098||||||||||||0.8839|EAS|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.199A>G||199|||||rs3131971|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.7532|0.5129|0.8127|0.8839|0.8419|0.8098||||||||||||0.8839|EAS|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs3131971|1||||SNV||||||||||||||||||0.7532|0.5129|0.8127|0.8839|0.8419|0.8098||||||||||||0.8839|EAS||||||||||||||||||||||||| 1 752915 . C T 316.6 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.165C>T||165|||||rs562478984|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0004|0|0.0029|0|0|0||||||||||||0.0029|AMR|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.178G>A||178|||||rs562478984|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0004|0|0.0029|0|0|0||||||||||||0.0029|AMR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs562478984|1||||SNV||||||||||||||||||0.0004|0|0.0029|0|0|0||||||||||||0.0029|AMR||||||||||||||||||||||||| 1 752918 . G T 181.34 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.168G>T||168|||||rs200599638|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0020|0|0|0.0099|0|0||||||||||||0.0099|EAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.175C>A||175|||||rs200599638|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0020|0|0|0.0099|0|0||||||||||||0.0099|EAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs200599638|1||||SNV||||||||||||||||||0.0020|0|0|0.0099|0|0||||||||||||0.0099|EAS||||||||||||||||||||||||| 1 752938 . G A 471.47 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.188G>A||188||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.155C>T||155||||||1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 752950 . C T 280.51 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.200C>T||200|||||rs548488495|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.143G>A||143|||||rs548488495|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs548488495|1||||SNV||||||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 752996 . T C 59.5 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.246T>C||246|||||rs569249172|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0016|0.0061|0|0|0|0||||||||||||0.0061|AFR|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.97A>G||97|||||rs569249172|1||-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0016|0.0061|0|0|0|0||||||||||||0.0061|AFR|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs569249172|1||||SNV||||||||||||||||||0.0016|0.0061|0|0|0|0||||||||||||0.0061|AFR||||||||||||||||||||||||| 1 753001 . GT G 43.25 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.255del||252||||||1||1||deletion|HGNC|32236|YES||||||||||||||3||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.91del||91||||||1||-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||deletion||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753016 . T C 40.09 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.266T>C||266|||||rs939878721|1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|1/2||ENST00000435300.1:n.77A>G||77|||||rs939878721|1||-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs939878721|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753110 . G A 55.21 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.360G>A||360|||||rs574650097|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0078|0.0295|0|0|0|0||||||||||||0.0295|AFR|||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs574650097|1|18|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0078|0.0295|0|0|0|0||||||||||||0.0295|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs574650097|1||||SNV||||||||||||||||||0.0078|0.0295|0|0|0|0||||||||||||0.0295|AFR||||||||||||||||||||||||| 1 753168 . C T 181.89 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.418C>T||418|||||rs554024631|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs554024631|1|76|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs554024631|1||||SNV||||||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 753174 . C T 505.57 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.424C>T||424|||||rs577155053|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,T|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs577155053|1|82|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs577155053|1||||SNV||||||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 753185 . G A 3893.97 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.435G>A||435|||||rs199998726|1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs199998726|1|93|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs199998726|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753235 . A G 14591.1 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.485A>G||485|||||rs200960205|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0010|0.0008|0.0014|0|0.002|0.001||||||||||||0.002|EUR|||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs200960205|1|143|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0010|0.0008|0.0014|0|0.002|0.001||||||||||||0.002|EUR|||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs200960205|1||||SNV||||||||||||||||||0.0010|0.0008|0.0014|0|0.002|0.001||||||||||||0.002|EUR||||||||||||||||||||||||| 1 753263 . T A 225.13 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.513T>A||513||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|171|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753269 . C G 4.94306e+06 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.519C>G||519|||||rs3115861|1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs3115861|1|177|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs3115861|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753291 . A C 3869.76 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.541A>C||541|||||rs200239555|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0006|0|0|0|0.003|0||||||||||||0.003|EUR|||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs200239555|1|199|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0006|0|0|0|0.003|0||||||||||||0.003|EUR|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs200239555|1||||SNV||||||||||||||||||0.0006|0|0|0|0.003|0||||||||||||0.003|EUR||||||||||||||||||||||||| 1 753338 . A G 2292.1 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.588A>G||588||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|246|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753405 . C A 4.26658e+06 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.655C>A||655|||||rs3115860|1||1||SNV|HGNC|32236|YES|||||||||||||||0.7518|0.4599|0.8228|0.8819|0.8708|0.8395||||||||||||0.8819|EAS||||20637081|||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs3115860|1|313|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.7518|0.4599|0.8228|0.8819|0.8708|0.8395||||||||||||0.8819|EAS||||20637081|||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs3115860|1||||SNV||||||||||||||||||0.7518|0.4599|0.8228|0.8819|0.8708|0.8395||||||||||||0.8819|EAS||||20637081||||||||||||||||||||| 1 753423 . T A 70.53 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.673T>A||673||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|331|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753424 . GT G 49.59 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.675del||675||||||1||1||deletion|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|333|-1||deletion|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||deletion||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753425 . T C 2.01763e+06 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.675T>C||675|||||rs3131970|1||1||SNV|HGNC|32236|YES|||||||||||||||0.749|0.4493|0.8228|0.8819|0.8708|0.8395||||||||||||0.8819|EAS|||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs3131970|1|333|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.749|0.4493|0.8228|0.8819|0.8708|0.8395||||||||||||0.8819|EAS|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs3131970|1||||SNV||||||||||||||||||0.749|0.4493|0.8228|0.8819|0.8708|0.8395||||||||||||0.8819|EAS||||||||||||||||||||||||| 1 753426 . G C 58.59 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.676G>C||676|||||rs904709250|1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs904709250|1|334|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs904709250|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753433 . G A 291.98 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.683G>A||683|||||rs546843995|1||1||SNV|HGNC|32236|YES|||||||||||||||0.0058|0.0219|0|0|0|0||||||||||||0.0219|AFR|||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs546843995|1|341|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.0058|0.0219|0|0|0|0||||||||||||0.0219|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs546843995|1||||SNV||||||||||||||||||0.0058|0.0219|0|0|0|0||||||||||||0.0219|AFR||||||||||||||||||||||||| 1 753444 . G A 322.62 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.694G>A||694||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|352|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 753474 . C G 2.17541e+06 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.724C>G||724|||||rs2073814|1||1||SNV|HGNC|32236|YES|||||||||||||||0.6114|0.1672|0.7233|0.7292|0.838|0.7781||||||||||||0.838|EUR|||||||||||||||||||||||||,G|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript||||||||||rs2073814|1|382|-1||SNV|Clone_based_vega_gene||YES|||||||||||||||0.6114|0.1672|0.7233|0.7292|0.838|0.7781||||||||||||0.838|EUR|||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region||||||||||rs2073814|1||||SNV||||||||||||||||||0.6114|0.1672|0.7233|0.7292|0.838|0.7781||||||||||||0.838|EUR||||||||||||||||||||||||| 1 753479 . G A 17459.8 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|FAM87B|ENSG00000177757|Transcript|ENST00000326734|lincRNA|1/2||ENST00000326734.1:n.729G>A||729||||||1||1||SNV|HGNC|32236|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|upstream_gene_variant|MODIFIER|RP11-206L10.10|ENSG00000240453|Transcript|ENST00000435300|processed_transcript|||||||||||1|387|-1||SNV|Clone_based_vega_gene||YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000344289|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762005 . G A 4893.37 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs183548767|1|983|1||SNV|HGNC|49377|YES|||||||||||||||0.0078|0.0295|0|0|0|0||||||||||||0.0295|AFR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.898C>T||898|||||rs183548767|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0078|0.0295|0|0|0|0||||||||||||0.0295|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs183548767|1||||SNV||||||||||||||||||0.0078|0.0295|0|0|0|0||||||||||||0.0295|AFR||||||||||||||||||||||||| 1 762008 . C T 303.04 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|980|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.895G>A||895||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762022 . T C 13954.3 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs186393233|1|966|1||SNV|HGNC|49377|YES|||||||||||||||0.0114|0.0424|0.0014|0|0|0||||||||||||0.0424|AFR|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.881A>G||881|||||rs186393233|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0114|0.0424|0.0014|0|0|0||||||||||||0.0424|AFR|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs186393233|1||||SNV||||||||||||||||||0.0114|0.0424|0.0014|0|0|0||||||||||||0.0424|AFR||||||||||||||||||||||||| 1 762031 . T C 193.97 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|957|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.872A>G||872||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762033 . C T 9403.43 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs567982258|1|955|1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0|0.001|0.001|||0.0006229|0|4.747e-05|0|0|0|8.083e-05|0|0.004706|0.004706|gnomAD_SAS|||||||||||||||rs567982258|6.53695e-04|4.56587e-03|0.00000e+00|4.61170e-05|0.00000e+00|0.00000e+00|0.00000e+00|7.42170e-05|0.00000e+00|4.56587e-03,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.870G>A||870|||||rs567982258|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0004|0|0|0|0.001|0.001|||0.0006229|0|4.747e-05|0|0|0|8.083e-05|0|0.004706|0.004706|gnomAD_SAS|||||||||||||||rs567982258|6.53695e-04|4.56587e-03|0.00000e+00|4.61170e-05|0.00000e+00|0.00000e+00|0.00000e+00|7.42170e-05|0.00000e+00|4.56587e-03,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs567982258|1||||SNV||||||||||||||||||0.0004|0|0|0|0.001|0.001|||0.0006229|0|4.747e-05|0|0|0|8.083e-05|0|0.004706|0.004706|gnomAD_SAS|||||||||||||||rs567982258|6.53695e-04|4.56587e-03|0.00000e+00|4.61170e-05|0.00000e+00|0.00000e+00|0.00000e+00|7.42170e-05|0.00000e+00|4.56587e-03 1 762037 . A G 6744 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs755554603|1|951|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.0001992|0|0.0003725|0|0|0|0.0003128|0.0006729|0|0.0006729|gnomAD_OTH|||||||||||||||rs755554603|1.59693e-04|4.07166e-04|0.00000e+00|4.07166e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.12035e-04|2.88184e-04|0.00000e+00,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.866T>C||866|||||rs755554603|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.0001992|0|0.0003725|0|0|0|0.0003128|0.0006729|0|0.0006729|gnomAD_OTH|||||||||||||||rs755554603|1.59693e-04|4.07166e-04|0.00000e+00|4.07166e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.12035e-04|2.88184e-04|0.00000e+00,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs755554603|1||||SNV||||||||||||||||||||||||||0.0001992|0|0.0003725|0|0|0|0.0003128|0.0006729|0|0.0006729|gnomAD_OTH|||||||||||||||rs755554603|1.59693e-04|4.07166e-04|0.00000e+00|4.07166e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.12035e-04|2.88184e-04|0.00000e+00 1 762038 . T C 1658.91 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|950|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1271867805|1.27670e-05|1.90042e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.90042e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.865A>G||865||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1271867805|1.27670e-05|1.90042e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.90042e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||rs1271867805|1.27670e-05|1.90042e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.90042e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 762045 . G A 784.88 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|943|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1359702600|1.27157e-05|2.24406e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.24406e-05|0.00000e+00|0.00000e+00,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.858C>T||858||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1359702600|1.27157e-05|2.24406e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.24406e-05|0.00000e+00|0.00000e+00,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||rs1359702600|1.27157e-05|2.24406e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.24406e-05|0.00000e+00|0.00000e+00 1 762052 . C G 613.93 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|936|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.851G>C||851||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762061 . T A 342833 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs191348624|1|927|1||SNV|HGNC|49377|YES|||||||||||||||0.0036|0|0.0101|0|0.0099|0.001|||0.006529|0.0007738|0.005745|0.004617|0|0.006494|0.00942|0.01018|0.005738|0.01018|gnomAD_OTH|||||||||||||||rs191348624|6.40176e-03|9.56030e-03|7.42942e-04|5.91866e-03|4.56882e-03|0.00000e+00|6.66854e-03|9.56030e-03|7.61035e-03|5.69874e-03,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.842A>T||842|||||rs191348624|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0036|0|0.0101|0|0.0099|0.001|||0.006529|0.0007738|0.005745|0.004617|0|0.006494|0.00942|0.01018|0.005738|0.01018|gnomAD_OTH|||||||||||||||rs191348624|6.40176e-03|9.56030e-03|7.42942e-04|5.91866e-03|4.56882e-03|0.00000e+00|6.66854e-03|9.56030e-03|7.61035e-03|5.69874e-03,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs191348624|1||||SNV||||||||||||||||||0.0036|0|0.0101|0|0.0099|0.001|||0.006529|0.0007738|0.005745|0.004617|0|0.006494|0.00942|0.01018|0.005738|0.01018|gnomAD_OTH|||||||||||||||rs191348624|6.40176e-03|9.56030e-03|7.42942e-04|5.91866e-03|4.56882e-03|0.00000e+00|6.66854e-03|9.56030e-03|7.61035e-03|5.69874e-03 1 762069 . C T 1953.94 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|919|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.834G>A||834||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762070 . A T 634.72 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs938085299|1|918|1||SNV|HGNC|49377|YES|||||||||||||||||||||||2.193e-05|0|0|0|0|0|5.963e-05|0|0|5.963e-05|gnomAD_NFE|||||||||||||||rs938085299|3.14043e-05|5.61629e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.61629e-05|0.00000e+00|0.00000e+00,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.833T>A||833|||||rs938085299|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||2.193e-05|0|0|0|0|0|5.963e-05|0|0|5.963e-05|gnomAD_NFE|||||||||||||||rs938085299|3.14043e-05|5.61629e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.61629e-05|0.00000e+00|0.00000e+00,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs938085299|1||||SNV||||||||||||||||||||||||||2.193e-05|0|0|0|0|0|5.963e-05|0|0|5.963e-05|gnomAD_NFE|||||||||||||||rs938085299|3.14043e-05|5.61629e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|5.61629e-05|0.00000e+00|0.00000e+00 1 762085 . G A 2229.66 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|903|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1455797252|6.86350e-05|1.22719e-04|0.00000e+00|1.22719e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.57769e-05|0.00000e+00|0.00000e+00,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.818C>T||818||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1455797252|6.86350e-05|1.22719e-04|0.00000e+00|1.22719e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.57769e-05|0.00000e+00|0.00000e+00,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||rs1455797252|6.86350e-05|1.22719e-04|0.00000e+00|1.22719e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.57769e-05|0.00000e+00|0.00000e+00 1 762092 . C T 565.9 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|896|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.811G>A||811||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762109 . C T 1.11312e+06 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs540936498|1|879|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.02222|0.02414|0.01234|0.05335|0.0005928|0.008235|0.02536|0.02779|0.03323|0.05335|gnomAD_ASJ|||||||||||||||rs540936498|3.42881e-02|3.31030e-02|2.42645e-02|1.17794e-02|5.48018e-02|5.56483e-04|8.25126e-03|2.60668e-02|3.13572e-02|3.31030e-02,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.794G>A||794|||||rs540936498|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.02222|0.02414|0.01234|0.05335|0.0005928|0.008235|0.02536|0.02779|0.03323|0.05335|gnomAD_ASJ|||||||||||||||rs540936498|3.42881e-02|3.31030e-02|2.42645e-02|1.17794e-02|5.48018e-02|5.56483e-04|8.25126e-03|2.60668e-02|3.13572e-02|3.31030e-02,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs540936498|1||||SNV||||||||||||||||||||||||||0.02222|0.02414|0.01234|0.05335|0.0005928|0.008235|0.02536|0.02779|0.03323|0.05335|gnomAD_ASJ|||||||||||||||rs540936498|3.42881e-02|3.31030e-02|2.42645e-02|1.17794e-02|5.48018e-02|5.56483e-04|8.25126e-03|2.60668e-02|3.13572e-02|3.31030e-02 1 762142 . C A 5418.62 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs182361907|1|846|1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0.002|0|0|||0.0003761|0|0|0|0.004741|0|0|0|0.0002657|0.004741|gnomAD_EAS|||||||||||||||rs182361907|3.72838e-04|4.82285e-03|0.00000e+00|0.00000e+00|0.00000e+00|4.82285e-03|0.00000e+00|0.00000e+00|0.00000e+00|2.66312e-04,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.761G>T||761|||||rs182361907|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0004|0|0|0.002|0|0|||0.0003761|0|0|0|0.004741|0|0|0|0.0002657|0.004741|gnomAD_EAS|||||||||||||||rs182361907|3.72838e-04|4.82285e-03|0.00000e+00|0.00000e+00|0.00000e+00|4.82285e-03|0.00000e+00|0.00000e+00|0.00000e+00|2.66312e-04,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs182361907|1||||SNV||||||||||||||||||0.0004|0|0|0.002|0|0|||0.0003761|0|0|0|0.004741|0|0|0|0.0002657|0.004741|gnomAD_EAS|||||||||||||||rs182361907|3.72838e-04|4.82285e-03|0.00000e+00|0.00000e+00|0.00000e+00|4.82285e-03|0.00000e+00|0.00000e+00|0.00000e+00|2.66312e-04 1 762159 . T C 24682.6 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs772658653|1|829|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.0001671|0|0.0002516|0|0|0|0.0003356|0|0|0.0003356|gnomAD_NFE|||||||||||||||rs772658653|1.55048e-04|3.17808e-04|0.00000e+00|2.03451e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.17808e-04|2.33754e-04|0.00000e+00,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.744A>G||744|||||rs772658653|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.0001671|0|0.0002516|0|0|0|0.0003356|0|0|0.0003356|gnomAD_NFE|||||||||||||||rs772658653|1.55048e-04|3.17808e-04|0.00000e+00|2.03451e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.17808e-04|2.33754e-04|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs772658653|1||||SNV||||||||||||||||||||||||||0.0001671|0|0.0002516|0|0|0|0.0003356|0|0|0.0003356|gnomAD_NFE|||||||||||||||rs772658653|1.55048e-04|3.17808e-04|0.00000e+00|2.03451e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.17808e-04|2.33754e-04|0.00000e+00 1 762175 . C G 518.88 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs576957487|1|813|1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0.0008|0|0|0|0|||4.874e-05|0.0009225|4.194e-05|0|0|0|0|0|0|0.0009225|gnomAD_AFR|||||||||||||||rs576957487|4.93291e-05|1.03397e-03|1.03397e-03|4.06901e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.728G>C||728|||||rs576957487|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0002|0.0008|0|0|0|0|||4.874e-05|0.0009225|4.194e-05|0|0|0|0|0|0|0.0009225|gnomAD_AFR|||||||||||||||rs576957487|4.93291e-05|1.03397e-03|1.03397e-03|4.06901e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs576957487|1||||SNV||||||||||||||||||0.0002|0.0008|0|0|0|0|||4.874e-05|0.0009225|4.194e-05|0|0|0|0|0|0|0.0009225|gnomAD_AFR|||||||||||||||rs576957487|4.93291e-05|1.03397e-03|1.03397e-03|4.06901e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 762187 . C T 36909.3 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs144015209|1|801|1||SNV|HGNC|49377|YES|||||||||||||||0.0048|0.0159|0.0043|0|0|0|||0.0007381|0.01352|0.000629|0|0|0|1.864e-05|0.0002672|4.427e-05|0.0159|AFR|||||||||||||||rs144015209|7.71284e-04|1.41802e-02|1.41802e-02|6.91732e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.76523e-05|0.00000e+00|4.43813e-05,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.716G>A||716|||||rs144015209|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0048|0.0159|0.0043|0|0|0|||0.0007381|0.01352|0.000629|0|0|0|1.864e-05|0.0002672|4.427e-05|0.0159|AFR|||||||||||||||rs144015209|7.71284e-04|1.41802e-02|1.41802e-02|6.91732e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.76523e-05|0.00000e+00|4.43813e-05,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs144015209|1||||SNV||||||||||||||||||0.0048|0.0159|0.0043|0|0|0|||0.0007381|0.01352|0.000629|0|0|0|1.864e-05|0.0002672|4.427e-05|0.0159|AFR|||||||||||||||rs144015209|7.71284e-04|1.41802e-02|1.41802e-02|6.91732e-04|0.00000e+00|0.00000e+00|0.00000e+00|1.76523e-05|0.00000e+00|4.43813e-05 1 762190 . C T 15953.6 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs369111582|1|798|1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0|0|0.002|||0.0005083|0|0|0|0|0|0|0|0.003232|0.003232|gnomAD_SAS|||||||||||||||rs369111582|4.58323e-04|3.28451e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.28451e-03,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.713G>A||713|||||rs369111582|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0004|0|0|0|0|0.002|||0.0005083|0|0|0|0|0|0|0|0.003232|0.003232|gnomAD_SAS|||||||||||||||rs369111582|4.58323e-04|3.28451e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.28451e-03,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs369111582|1||||SNV||||||||||||||||||0.0004|0|0|0|0|0.002|||0.0005083|0|0|0|0|0|0|0|0.003232|0.003232|gnomAD_SAS|||||||||||||||rs369111582|4.58323e-04|3.28451e-03|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.28451e-03 1 762199 . T C 4267.48 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs1037269403|1|789|1||SNV|HGNC|49377|YES|||||||||||||||||||||||4.178e-05|0|0|0|0|0|0.0001119|0|0|0.0001119|gnomAD_NFE|||||||||||||||rs1037269403|3.67017e-05|8.82737e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|8.82737e-05|0.00000e+00|0.00000e+00,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.704A>G||704|||||rs1037269403|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||4.178e-05|0|0|0|0|0|0.0001119|0|0|0.0001119|gnomAD_NFE|||||||||||||||rs1037269403|3.67017e-05|8.82737e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|8.82737e-05|0.00000e+00|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs1037269403|1||||SNV||||||||||||||||||||||||||4.178e-05|0|0|0|0|0|0.0001119|0|0|0.0001119|gnomAD_NFE|||||||||||||||rs1037269403|3.67017e-05|8.82737e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|8.82737e-05|0.00000e+00|0.00000e+00 1 762203 . T C 2028.86 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|785|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1396524089|6.11913e-06|1.76547e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.76547e-05|0.00000e+00|0.00000e+00,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.700A>G||700||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1396524089|6.11913e-06|1.76547e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.76547e-05|0.00000e+00|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||rs1396524089|6.11913e-06|1.76547e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.76547e-05|0.00000e+00|0.00000e+00 1 762211 . C A 508.88 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|777|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.692G>T||692||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762215 . A T 22491.1 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs575898435|1|773|1||SNV|HGNC|49377|YES|||||||||||||||0.0016|0|0|0|0|0.0082|||0.0008569|0|4.194e-05|0|0|0|3.731e-05|0.0005345|0.005224|0.0082|SAS|||||||||||||||rs575898435|7.84832e-04|5.32576e-03|0.00000e+00|4.06934e-05|0.00000e+00|0.00000e+00|0.00000e+00|7.06589e-05|4.67727e-04|5.32576e-03,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.688T>A||688|||||rs575898435|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0016|0|0|0|0|0.0082|||0.0008569|0|4.194e-05|0|0|0|3.731e-05|0.0005345|0.005224|0.0082|SAS|||||||||||||||rs575898435|7.84832e-04|5.32576e-03|0.00000e+00|4.06934e-05|0.00000e+00|0.00000e+00|0.00000e+00|7.06589e-05|4.67727e-04|5.32576e-03,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs575898435|1||||SNV||||||||||||||||||0.0016|0|0|0|0|0.0082|||0.0008569|0|4.194e-05|0|0|0|3.731e-05|0.0005345|0.005224|0.0082|SAS|||||||||||||||rs575898435|7.84832e-04|5.32576e-03|0.00000e+00|4.06934e-05|0.00000e+00|0.00000e+00|0.00000e+00|7.06589e-05|4.67727e-04|5.32576e-03 1 762222 . T C 7619.64 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs766326531|1|766|1||SNV|HGNC|49377|YES|||||||||||||||||||||||2.786e-05|0|0|0|0|0|7.462e-05|0|0|7.462e-05|gnomAD_NFE|||||||||||||||rs766326531|3.09429e-05|7.06539e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|7.06539e-05|0.00000e+00|0.00000e+00,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.681A>G||681|||||rs766326531|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||2.786e-05|0|0|0|0|0|7.462e-05|0|0|7.462e-05|gnomAD_NFE|||||||||||||||rs766326531|3.09429e-05|7.06539e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|7.06539e-05|0.00000e+00|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs766326531|1||||SNV||||||||||||||||||||||||||2.786e-05|0|0|0|0|0|7.462e-05|0|0|7.462e-05|gnomAD_NFE|||||||||||||||rs766326531|3.09429e-05|7.06539e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|7.06539e-05|0.00000e+00|0.00000e+00 1 762224 . C T 1265.86 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|764|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.679G>A||679||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762249 . C T 1078.19 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs1049900411|1|739|1||SNV|HGNC|49377|YES|||||||||||||||||||||||6.967e-06|0|0|0|0|0|1.866e-05|0|0|1.866e-05|gnomAD_NFE|||||||||||||||rs1049900411|6.28733e-06|1.76647e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.76647e-05|0.00000e+00|0.00000e+00,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.654G>A||654|||||rs1049900411|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||6.967e-06|0|0|0|0|0|1.866e-05|0|0|1.866e-05|gnomAD_NFE|||||||||||||||rs1049900411|6.28733e-06|1.76647e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.76647e-05|0.00000e+00|0.00000e+00,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs1049900411|1||||SNV||||||||||||||||||||||||||6.967e-06|0|0|0|0|0|1.866e-05|0|0|1.866e-05|gnomAD_NFE|||||||||||||||rs1049900411|6.28733e-06|1.76647e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.76647e-05|0.00000e+00|0.00000e+00 1 762262 . C G 563.02 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|726|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.641G>C||641||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762273 . G A 2.56606e+07 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs3115849|1|715|1||SNV|HGNC|49377|YES|||||||||||||||0.7318|0.3903|0.8112|0.8879|0.8688|0.8354|||0.8183|0.4137|0.7954|0.8442|0.897|0.803|0.8606|0.8305|0.8174|0.897|gnomAD_EAS|||||||||||||||rs3115849|8.00616e-01|8.97379e-01|4.13735e-01|7.95729e-01|8.42929e-01|8.97379e-01|8.04256e-01|8.59767e-01|8.38923e-01|8.17522e-01,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.630C>T||630|||||rs3115849|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.7318|0.3903|0.8112|0.8879|0.8688|0.8354|||0.8183|0.4137|0.7954|0.8442|0.897|0.803|0.8606|0.8305|0.8174|0.897|gnomAD_EAS|||||||||||||||rs3115849|8.00616e-01|8.97379e-01|4.13735e-01|7.95729e-01|8.42929e-01|8.97379e-01|8.04256e-01|8.59767e-01|8.38923e-01|8.17522e-01,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs3115849|1||||SNV||||||||||||||||||0.7318|0.3903|0.8112|0.8879|0.8688|0.8354|||0.8183|0.4137|0.7954|0.8442|0.897|0.803|0.8606|0.8305|0.8174|0.897|gnomAD_EAS|||||||||||||||rs3115849|8.00616e-01|8.97379e-01|4.13735e-01|7.95729e-01|8.42929e-01|8.97379e-01|8.04256e-01|8.59767e-01|8.38923e-01|8.17522e-01 1 762277 . C T 288.96 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs376499074|1|711|1||SNV|HGNC|49377|YES|||||||||||||||||||||||4.878e-05|0|0|0|0.0004948|0|1.867e-05|0.0002675|0|0.0004948|gnomAD_EAS|||||||||||||||rs376499074|1.70806e-04|4.64511e-04|0.00000e+00|0.00000e+00|0.00000e+00|4.64511e-04|0.00000e+00|1.76741e-05|2.34082e-04|0.00000e+00,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.626G>A||626|||||rs376499074|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||4.878e-05|0|0|0|0.0004948|0|1.867e-05|0.0002675|0|0.0004948|gnomAD_EAS|||||||||||||||rs376499074|1.70806e-04|4.64511e-04|0.00000e+00|0.00000e+00|0.00000e+00|4.64511e-04|0.00000e+00|1.76741e-05|2.34082e-04|0.00000e+00,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs376499074|1||||SNV||||||||||||||||||||||||||4.878e-05|0|0|0|0.0004948|0|1.867e-05|0.0002675|0|0.0004948|gnomAD_EAS|||||||||||||||rs376499074|1.70806e-04|4.64511e-04|0.00000e+00|0.00000e+00|0.00000e+00|4.64511e-04|0.00000e+00|1.76741e-05|2.34082e-04|0.00000e+00 1 762292 . G C 887.74 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|696|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.611C>G||611||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762307 . G A 4400.71 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs752298129|1|681|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.001032|0.01788|0.001007|0|0.0003958|0|5.599e-05|0.0002675|0|0.01788|gnomAD_AFR|||||||||||||||rs752298129|1.23242e-03|1.73333e-02|1.73333e-02|9.77517e-04|0.00000e+00|3.71609e-04|0.00000e+00|5.30166e-05|7.02247e-04|0.00000e+00,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.596C>T||596|||||rs752298129|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.001032|0.01788|0.001007|0|0.0003958|0|5.599e-05|0.0002675|0|0.01788|gnomAD_AFR|||||||||||||||rs752298129|1.23242e-03|1.73333e-02|1.73333e-02|9.77517e-04|0.00000e+00|3.71609e-04|0.00000e+00|5.30166e-05|7.02247e-04|0.00000e+00,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs752298129|1||||SNV||||||||||||||||||||||||||0.001032|0.01788|0.001007|0|0.0003958|0|5.599e-05|0.0002675|0|0.01788|gnomAD_AFR|||||||||||||||rs752298129|1.23242e-03|1.73333e-02|1.73333e-02|9.77517e-04|0.00000e+00|3.71609e-04|0.00000e+00|5.30166e-05|7.02247e-04|0.00000e+00 1 762320 . C T 118646 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs75333668|1|668|1||SNV|HGNC|49377|YES|||||||||||||||0.0695|0.1029|0.072|0.128|0.001|0.0327|||0.02988|0.0743|0.07251|0.006668|0.1438|0.0001995|0.001418|0.02675|0.01776|0.1438|gnomAD_EAS|||||||||||||||rs75333668|2.90131e-02|1.43990e-01|7.41018e-02|7.19583e-02|6.80029e-03|1.43990e-01|2.62158e-04|1.43094e-03|2.43332e-02|1.80236e-02,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.583G>A||583|||||rs75333668|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0695|0.1029|0.072|0.128|0.001|0.0327|||0.02988|0.0743|0.07251|0.006668|0.1438|0.0001995|0.001418|0.02675|0.01776|0.1438|gnomAD_EAS|||||||||||||||rs75333668|2.90131e-02|1.43990e-01|7.41018e-02|7.19583e-02|6.80029e-03|1.43990e-01|2.62158e-04|1.43094e-03|2.43332e-02|1.80236e-02,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs75333668|1||||SNV||||||||||||||||||0.0695|0.1029|0.072|0.128|0.001|0.0327|||0.02988|0.0743|0.07251|0.006668|0.1438|0.0001995|0.001418|0.02675|0.01776|0.1438|gnomAD_EAS|||||||||||||||rs75333668|2.90131e-02|1.43990e-01|7.41018e-02|7.19583e-02|6.80029e-03|1.43990e-01|2.62158e-04|1.43094e-03|2.43332e-02|1.80236e-02 1 762330 . G T 178874 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs74045217|1|658|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.01212|0.1595|0.01162|0.01111|0|0.003798|0.003643|0.01285|0.001638|0.1595|gnomAD_AFR|||||||||||||||rs74045217|1.21320e-02|1.59751e-01|1.59751e-01|1.13618e-02|1.14504e-02|0.00000e+00|3.94063e-03|3.66255e-03|1.17096e-02|1.64269e-03,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.573C>A||573|||||rs74045217|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.01212|0.1595|0.01162|0.01111|0|0.003798|0.003643|0.01285|0.001638|0.1595|gnomAD_AFR|||||||||||||||rs74045217|1.21320e-02|1.59751e-01|1.59751e-01|1.13618e-02|1.14504e-02|0.00000e+00|3.94063e-03|3.66255e-03|1.17096e-02|1.64269e-03,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs74045217|1||||SNV||||||||||||||||||||||||||0.01212|0.1595|0.01162|0.01111|0|0.003798|0.003643|0.01285|0.001638|0.1595|gnomAD_AFR|||||||||||||||rs74045217|1.21320e-02|1.59751e-01|1.59751e-01|1.13618e-02|1.14504e-02|0.00000e+00|3.94063e-03|3.66255e-03|1.17096e-02|1.64269e-03 1 762339 . T C 580.94 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|649|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.564A>G||564||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762345 . A G 199030 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs74045218|1|643|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.01466|0.2044|0.01386|0.01111|0|0.00385|0.003937|0.01395|0.001595|0.2044|gnomAD_AFR|||||||||||||||rs74045218|1.49284e-02|2.04194e-01|2.04194e-01|1.35719e-02|1.14531e-02|0.00000e+00|3.99574e-03|3.95966e-03|1.33929e-02|1.59872e-03,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.558T>C||558|||||rs74045218|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.01466|0.2044|0.01386|0.01111|0|0.00385|0.003937|0.01395|0.001595|0.2044|gnomAD_AFR|||||||||||||||rs74045218|1.49284e-02|2.04194e-01|2.04194e-01|1.35719e-02|1.14531e-02|0.00000e+00|3.99574e-03|3.95966e-03|1.33929e-02|1.59872e-03,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs74045218|1||||SNV||||||||||||||||||||||||||0.01466|0.2044|0.01386|0.01111|0|0.00385|0.003937|0.01395|0.001595|0.2044|gnomAD_AFR|||||||||||||||rs74045218|1.49284e-02|2.04194e-01|2.04194e-01|1.35719e-02|1.14531e-02|0.00000e+00|3.99574e-03|3.95966e-03|1.33929e-02|1.59872e-03 1 762352 . C G 1420.1 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs572362184|1|636|1||SNV|HGNC|49377|YES|||||||||||||||0.0056|0.0212|0|0|0|0|||0.0008993|0.01702|0.0006713|0|0|0|3.733e-05|0.0002675|0|0.0212|AFR|||||||||||||||rs572362184|9.62366e-04|1.64982e-02|1.64982e-02|6.51466e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.53469e-05|7.02905e-04|0.00000e+00,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.551G>C||551|||||rs572362184|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0056|0.0212|0|0|0|0|||0.0008993|0.01702|0.0006713|0|0|0|3.733e-05|0.0002675|0|0.0212|AFR|||||||||||||||rs572362184|9.62366e-04|1.64982e-02|1.64982e-02|6.51466e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.53469e-05|7.02905e-04|0.00000e+00,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs572362184|1||||SNV||||||||||||||||||0.0056|0.0212|0|0|0|0|||0.0008993|0.01702|0.0006713|0|0|0|3.733e-05|0.0002675|0|0.0212|AFR|||||||||||||||rs572362184|9.62366e-04|1.64982e-02|1.64982e-02|6.51466e-04|0.00000e+00|0.00000e+00|0.00000e+00|3.53469e-05|7.02905e-04|0.00000e+00 1 762366 . G C 2219.58 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs541509014|1|622|1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0|0.002|0|||0.0004125|0|0|0|0|0.003135|0.0001876|0.0005365|0|0.003135|gnomAD_FIN|||||||||||||||rs541509014|3.89453e-04|1.95306e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.22156e-03|1.95306e-04|2.34962e-04|0.00000e+00,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.537C>G||537|||||rs541509014|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0004|0|0|0|0.002|0|||0.0004125|0|0|0|0|0.003135|0.0001876|0.0005365|0|0.003135|gnomAD_FIN|||||||||||||||rs541509014|3.89453e-04|1.95306e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.22156e-03|1.95306e-04|2.34962e-04|0.00000e+00,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs541509014|1||||SNV||||||||||||||||||0.0004|0|0|0|0.002|0|||0.0004125|0|0|0|0|0.003135|0.0001876|0.0005365|0|0.003135|gnomAD_FIN|||||||||||||||rs541509014|3.89453e-04|1.95306e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|3.22156e-03|1.95306e-04|2.34962e-04|0.00000e+00 1 762383 . T C 129.14 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|605|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.520A>G||520||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762409 . G C 45266.9 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs563839199|1|579|1||SNV|HGNC|49377|YES|||||||||||||||0.0036|0|0.0101|0|0.0099|0.001|||0.006625|0.0007754|0.00596|0.004986|0|0.006548|0.009415|0.01074|0.005755|0.01074|gnomAD_OTH|||||||||||||||rs563839199|6.24377e-03|9.57484e-03|7.44934e-04|6.17337e-03|4.91938e-03|0.00000e+00|6.71838e-03|9.57484e-03|7.80463e-03|5.72170e-03,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.494C>G||494|||||rs563839199|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0036|0|0.0101|0|0.0099|0.001|||0.006625|0.0007754|0.00596|0.004986|0|0.006548|0.009415|0.01074|0.005755|0.01074|gnomAD_OTH|||||||||||||||rs563839199|6.24377e-03|9.57484e-03|7.44934e-04|6.17337e-03|4.91938e-03|0.00000e+00|6.71838e-03|9.57484e-03|7.80463e-03|5.72170e-03,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs563839199|1||||SNV||||||||||||||||||0.0036|0|0.0101|0|0.0099|0.001|||0.006625|0.0007754|0.00596|0.004986|0|0.006548|0.009415|0.01074|0.005755|0.01074|gnomAD_OTH|||||||||||||||rs563839199|6.24377e-03|9.57484e-03|7.44934e-04|6.17337e-03|4.91938e-03|0.00000e+00|6.71838e-03|9.57484e-03|7.80463e-03|5.72170e-03 1 762413 . G A 120.11 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|575|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.490C>T||490||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762418 . G A 196.14 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|570|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.485C>T||485||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762423 . C A 66.01 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs549701190|1|565|1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0|0|0.002|||5.249e-05|0|0|0|0|0|0|0.0002899|0.0002878|0.002|SAS|||||||||||||||rs549701190|4.24587e-05|2.88434e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.52270e-04|2.88434e-04,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.480G>T||480|||||rs549701190|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0004|0|0|0|0|0.002|||5.249e-05|0|0|0|0|0|0|0.0002899|0.0002878|0.002|SAS|||||||||||||||rs549701190|4.24587e-05|2.88434e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.52270e-04|2.88434e-04,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs549701190|1||||SNV||||||||||||||||||0.0004|0|0|0|0|0.002|||5.249e-05|0|0|0|0|0|0|0.0002899|0.0002878|0.002|SAS|||||||||||||||rs549701190|4.24587e-05|2.88434e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.52270e-04|2.88434e-04 1 762426 . C T 136.04 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|562|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.477G>A||477||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762446 . G C 105.99 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|542|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.457C>G||457||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762449 . G C 414.02 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|539|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.454C>G||454||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762460 . C A 43.48 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|528|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1261365843|6.21223e-05|1.85605e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.85605e-05|0.00000e+00|0.00000e+00,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.443G>T||443||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||rs1261365843|6.21223e-05|1.85605e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.85605e-05|0.00000e+00|0.00000e+00,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV|||||||||||||||||||||||||||||||||||||||||||||||||||rs1261365843|6.21223e-05|1.85605e-05|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|1.85605e-05|0.00000e+00|0.00000e+00 1 762465 . G A 339.01 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|523|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.438C>T||438||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762469 . G A 67.3 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs772938170|1|519|1||SNV|HGNC|49377|YES|||||||||||||||||||||||7.255e-06|0.0001552|0|0|0|0|0|0|0|0.0001552|gnomAD_AFR|||||||||||||||rs772938170|1.67881e-05|1.48898e-04|1.48898e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.434C>T||434|||||rs772938170|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||7.255e-06|0.0001552|0|0|0|0|0|0|0|0.0001552|gnomAD_AFR|||||||||||||||rs772938170|1.67881e-05|1.48898e-04|1.48898e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs772938170|1||||SNV||||||||||||||||||||||||||7.255e-06|0.0001552|0|0|0|0|0|0|0|0.0001552|gnomAD_AFR|||||||||||||||rs772938170|1.67881e-05|1.48898e-04|1.48898e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 762472 . C T 32348.9 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs145493205|1|516|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.1093|0.297|0.1542|0.07741|0.09608|0.05551|0.08319|0.1047|0.1186|0.297|gnomAD_AFR|||||||||||||||rs145493205|1.09919e-01|2.97940e-01|2.97940e-01|1.54011e-01|8.02382e-02|9.47607e-02|5.53673e-02|8.60809e-02|1.03010e-01|1.18507e-01,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.431G>A||431|||||rs145493205|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.1093|0.297|0.1542|0.07741|0.09608|0.05551|0.08319|0.1047|0.1186|0.297|gnomAD_AFR|||||||||||||||rs145493205|1.09919e-01|2.97940e-01|2.97940e-01|1.54011e-01|8.02382e-02|9.47607e-02|5.53673e-02|8.60809e-02|1.03010e-01|1.18507e-01,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs145493205|1||||SNV||||||||||||||||||||||||||0.1093|0.297|0.1542|0.07741|0.09608|0.05551|0.08319|0.1047|0.1186|0.297|gnomAD_AFR|||||||||||||||rs145493205|1.09919e-01|2.97940e-01|2.97940e-01|1.54011e-01|8.02382e-02|9.47607e-02|5.53673e-02|8.60809e-02|1.03010e-01|1.18507e-01 1 762475 . G T 70 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|513|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.428C>A||428||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762485 . C A 45454.7 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs12095200|1|503|1||SNV|HGNC|49377|YES|||||||||||||||0.1661|0.3185|0.121|0.0982|0.0954|0.135|||0.116|0.3569|0.1599|0.08005|0.09526|0.05902|0.08856|0.1138|0.1178|0.3569|gnomAD_AFR|||||||||||||||rs12095200|1.15100e-01|3.57596e-01|3.57596e-01|1.59534e-01|8.35274e-02|9.40594e-02|5.89544e-02|9.12302e-02|1.09737e-01|1.17690e-01,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.418G>T||418|||||rs12095200|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.1661|0.3185|0.121|0.0982|0.0954|0.135|||0.116|0.3569|0.1599|0.08005|0.09526|0.05902|0.08856|0.1138|0.1178|0.3569|gnomAD_AFR|||||||||||||||rs12095200|1.15100e-01|3.57596e-01|3.57596e-01|1.59534e-01|8.35274e-02|9.40594e-02|5.89544e-02|9.12302e-02|1.09737e-01|1.17690e-01,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs12095200|1||||SNV||||||||||||||||||0.1661|0.3185|0.121|0.0982|0.0954|0.135|||0.116|0.3569|0.1599|0.08005|0.09526|0.05902|0.08856|0.1138|0.1178|0.3569|gnomAD_AFR|||||||||||||||rs12095200|1.15100e-01|3.57596e-01|3.57596e-01|1.59534e-01|8.35274e-02|9.40594e-02|5.89544e-02|9.12302e-02|1.09737e-01|1.17690e-01 1 762486 . A G 1182.98 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs527335721|1|502|1||SNV|HGNC|49377|YES|||||||||||||||0.0032|0.0121|0|0|0|0|||0.0003115|0.003467|0.0003982|0.0005566|0|0|8.009e-05|0.0008601|0|0.0121|AFR|||||||||||||||rs527335721|5.04626e-04|3.32628e-03|3.32628e-03|3.87063e-04|5.35619e-04|0.00000e+00|0.00000e+00|7.53608e-05|7.48877e-04|0.00000e+00,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.417T>C||417|||||rs527335721|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0032|0.0121|0|0|0|0|||0.0003115|0.003467|0.0003982|0.0005566|0|0|8.009e-05|0.0008601|0|0.0121|AFR|||||||||||||||rs527335721|5.04626e-04|3.32628e-03|3.32628e-03|3.87063e-04|5.35619e-04|0.00000e+00|0.00000e+00|7.53608e-05|7.48877e-04|0.00000e+00,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs527335721|1||||SNV||||||||||||||||||0.0032|0.0121|0|0|0|0|||0.0003115|0.003467|0.0003982|0.0005566|0|0|8.009e-05|0.0008601|0|0.0121|AFR|||||||||||||||rs527335721|5.04626e-04|3.32628e-03|3.32628e-03|3.87063e-04|5.35619e-04|0.00000e+00|0.00000e+00|7.53608e-05|7.48877e-04|0.00000e+00 1 762489 . G C 105.19 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs570489858|1|499|1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0|0|0|0|0.001|||3.75e-05|0|0|0|0|0|0|0|0.0002426|0.001|SAS|||||||||||||||rs570489858|3.94753e-05|2.43309e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.43309e-04,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.414C>G||414|||||rs570489858|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0002|0|0|0|0|0.001|||3.75e-05|0|0|0|0|0|0|0|0.0002426|0.001|SAS|||||||||||||||rs570489858|3.94753e-05|2.43309e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.43309e-04,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs570489858|1||||SNV||||||||||||||||||0.0002|0|0|0|0|0.001|||3.75e-05|0|0|0|0|0|0|0|0.0002426|0.001|SAS|||||||||||||||rs570489858|3.94753e-05|2.43309e-04|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|2.43309e-04 1 762494 . C G 3971.74 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs758032623|1|494|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.003155|0.05809|0.001679|0|0|0|6.181e-05|0.001477|4.94e-05|0.05809|gnomAD_AFR|||||||||||||||rs758032623|2.77002e-03|5.87791e-02|5.87791e-02|1.76632e-03|0.00000e+00|0.00000e+00|0.00000e+00|7.73844e-05|1.02828e-03|4.95246e-05,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.409G>C||409|||||rs758032623|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.003155|0.05809|0.001679|0|0|0|6.181e-05|0.001477|4.94e-05|0.05809|gnomAD_AFR|||||||||||||||rs758032623|2.77002e-03|5.87791e-02|5.87791e-02|1.76632e-03|0.00000e+00|0.00000e+00|0.00000e+00|7.73844e-05|1.02828e-03|4.95246e-05,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs758032623|1||||SNV||||||||||||||||||||||||||0.003155|0.05809|0.001679|0|0|0|6.181e-05|0.001477|4.94e-05|0.05809|gnomAD_AFR|||||||||||||||rs758032623|2.77002e-03|5.87791e-02|5.87791e-02|1.76632e-03|0.00000e+00|0.00000e+00|0.00000e+00|7.73844e-05|1.02828e-03|4.95246e-05 1 762523 . T A 2378.76 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs757587549|1|465|1||SNV|HGNC|49377|YES|||||||||||||||||||||||0.001285|0|0.0001074|0.001786|0|0.006141|0.001221|0.0003349|0.0001149|0.006141|gnomAD_FIN|||||||||||||||rs757587549|1.00733e-03|1.22367e-03|0.00000e+00|1.04723e-04|1.69549e-03|0.00000e+00|6.19286e-03|1.22367e-03|5.80720e-04|1.15141e-04,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.380A>T||380|||||rs757587549|1||-1||SNV|HGNC|26211|YES|||||||||||||||||||||||0.001285|0|0.0001074|0.001786|0|0.006141|0.001221|0.0003349|0.0001149|0.006141|gnomAD_FIN|||||||||||||||rs757587549|1.00733e-03|1.22367e-03|0.00000e+00|1.04723e-04|1.69549e-03|0.00000e+00|6.19286e-03|1.22367e-03|5.80720e-04|1.15141e-04,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs757587549|1||||SNV||||||||||||||||||||||||||0.001285|0|0.0001074|0.001786|0|0.006141|0.001221|0.0003349|0.0001149|0.006141|gnomAD_FIN|||||||||||||||rs757587549|1.00733e-03|1.22367e-03|0.00000e+00|1.04723e-04|1.69549e-03|0.00000e+00|6.19286e-03|1.22367e-03|5.80720e-04|1.15141e-04 1 762538 . G A 125.35 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs555417329|1|450|1||SNV|HGNC|49377|YES|||||||||||||||0.0032|0.0121|0|0|0|0|||0.0005828|0.006831|0.0004591|0|0|0|3.25e-05|0.0004822|9.891e-05|0.0121|AFR|||||||||||||||rs555417329|3.60446e-04|6.83816e-03|6.83816e-03|4.54339e-04|0.00000e+00|0.00000e+00|0.00000e+00|2.93669e-05|3.93391e-04|9.90295e-05,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.365C>T||365|||||rs555417329|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0032|0.0121|0|0|0|0|||0.0005828|0.006831|0.0004591|0|0|0|3.25e-05|0.0004822|9.891e-05|0.0121|AFR|||||||||||||||rs555417329|3.60446e-04|6.83816e-03|6.83816e-03|4.54339e-04|0.00000e+00|0.00000e+00|0.00000e+00|2.93669e-05|3.93391e-04|9.90295e-05,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs555417329|1||||SNV||||||||||||||||||0.0032|0.0121|0|0|0|0|||0.0005828|0.006831|0.0004591|0|0|0|3.25e-05|0.0004822|9.891e-05|0.0121|AFR|||||||||||||||rs555417329|3.60446e-04|6.83816e-03|6.83816e-03|4.54339e-04|0.00000e+00|0.00000e+00|0.00000e+00|2.93669e-05|3.93391e-04|9.90295e-05 1 762588 . AGGC A 8732.19 PASS CSQ=-|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs772021405|1|397|1||deletion|HGNC|49377|YES|||||||||||||||||||||||0|0|0|0|0|0|0|0|0||gnomAD_AFR&gnomAD_AMR&gnomAD_ASJ&gnomAD_EAS&gnomAD_FIN&gnomAD_NFE&gnomAD_OTH&gnomAD_SAS|||||||||||||||rs772021405|1.36516e-03||0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,-|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.312_314del||312-314|||||rs772021405|1||-1||deletion|HGNC|26211|YES|||||||||||||||||||||||0|0|0|0|0|0|0|0|0||gnomAD_AFR&gnomAD_AMR&gnomAD_ASJ&gnomAD_EAS&gnomAD_FIN&gnomAD_NFE&gnomAD_OTH&gnomAD_SAS|||||||||||||||rs772021405|1.36516e-03||0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00,-|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs772021405|1||||deletion||||||||||||||||||||||||||0|0|0|0|0|0|0|0|0||gnomAD_AFR&gnomAD_AMR&gnomAD_ASJ&gnomAD_EAS&gnomAD_FIN&gnomAD_NFE&gnomAD_OTH&gnomAD_SAS|||||||||||||||rs772021405|1.36516e-03||0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00|0.00000e+00 1 762589 . G C,* 5.39368e+06 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs3115848|1|399|1||sequence_alteration|HGNC|49377|YES|||||||||||||||0.7516|0.4584|0.8156|0.8879|0.8718|0.8384|||0.8065|0.452|0.7926|0.8423|0.8941|0.8015|0.8575|0.8255|0.8085|0.8941|gnomAD_EAS|||||||||||||||rs3115848|7.69023e-01|8.93900e-01|4.51000e-01|7.92074e-01|8.39772e-01|8.93900e-01|8.02765e-01|8.56203e-01|8.39224e-01|8.08254e-01,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.314C>G||314|||||rs3115848|1||-1||sequence_alteration|HGNC|26211|YES|||||||||||||||0.7516|0.4584|0.8156|0.8879|0.8718|0.8384|||0.8065|0.452|0.7926|0.8423|0.8941|0.8015|0.8575|0.8255|0.8085|0.8941|gnomAD_EAS|||||||||||||||rs3115848|7.69023e-01|8.93900e-01|4.51000e-01|7.92074e-01|8.39772e-01|8.93900e-01|8.02765e-01|8.56203e-01|8.39224e-01|8.08254e-01,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs3115848|1||||sequence_alteration||||||||||||||||||0.7516|0.4584|0.8156|0.8879|0.8718|0.8384|||0.8065|0.452|0.7926|0.8423|0.8941|0.8015|0.8575|0.8255|0.8085|0.8941|gnomAD_EAS|||||||||||||||rs3115848|7.69023e-01|8.93900e-01|4.51000e-01|7.92074e-01|8.39772e-01|8.93900e-01|8.02765e-01|8.56203e-01|8.39224e-01|8.08254e-01 1 762592 . C G 5.2699e+06 PASS CSQ=G|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs3131950|1|396|1||SNV|HGNC|49377|YES|||||||||||||||0.7516|0.4584|0.8156|0.8879|0.8718|0.8384|||0.8062|0.452|0.7933|0.8387|0.8943|0.8009|0.8581|0.8274|0.8081|0.8943|gnomAD_EAS|||||||||||||||rs3131950|7.74414e-01|8.93899e-01|4.51161e-01|7.93173e-01|8.37928e-01|8.93899e-01|8.02156e-01|8.56759e-01|8.40606e-01|8.07831e-01,G|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.311G>C||311|||||rs3131950|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.7516|0.4584|0.8156|0.8879|0.8718|0.8384|||0.8062|0.452|0.7933|0.8387|0.8943|0.8009|0.8581|0.8274|0.8081|0.8943|gnomAD_EAS|||||||||||||||rs3131950|7.74414e-01|8.93899e-01|4.51161e-01|7.93173e-01|8.37928e-01|8.93899e-01|8.02156e-01|8.56759e-01|8.40606e-01|8.07831e-01,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs3131950|1||||SNV||||||||||||||||||0.7516|0.4584|0.8156|0.8879|0.8718|0.8384|||0.8062|0.452|0.7933|0.8387|0.8943|0.8009|0.8581|0.8274|0.8081|0.8943|gnomAD_EAS|||||||||||||||rs3131950|7.74414e-01|8.93899e-01|4.51161e-01|7.93173e-01|8.37928e-01|8.93899e-01|8.02156e-01|8.56759e-01|8.40606e-01|8.07831e-01 1 762595 . G T 64.93 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|393|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.308C>A||308||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762601 . T C 4.23028e+06 PASS CSQ=C|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs3131949|1|387|1||SNV|HGNC|49377|YES||||||||||||||||0.4584|0.8156|0.8879|0.8718|0.8384|||0.8056|0.4518|0.7934|0.8391|0.8944|0.7986|0.8579|0.8252|0.8092|0.8944|gnomAD_EAS|||||||||||||||rs3131949|7.74976e-01|8.94005e-01|4.51349e-01|7.93448e-01|8.37719e-01|8.94005e-01|7.99962e-01|8.56534e-01|8.39623e-01|8.08898e-01,C|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.302A>G||302|||||rs3131949|1||-1||SNV|HGNC|26211|YES||||||||||||||||0.4584|0.8156|0.8879|0.8718|0.8384|||0.8056|0.4518|0.7934|0.8391|0.8944|0.7986|0.8579|0.8252|0.8092|0.8944|gnomAD_EAS|||||||||||||||rs3131949|7.74976e-01|8.94005e-01|4.51349e-01|7.93448e-01|8.37719e-01|8.94005e-01|7.99962e-01|8.56534e-01|8.39623e-01|8.08898e-01,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs3131949|1||||SNV|||||||||||||||||||0.4584|0.8156|0.8879|0.8718|0.8384|||0.8056|0.4518|0.7934|0.8391|0.8944|0.7986|0.8579|0.8252|0.8092|0.8944|gnomAD_EAS|||||||||||||||rs3131949|7.74976e-01|8.94005e-01|4.51349e-01|7.93448e-01|8.37719e-01|8.94005e-01|7.99962e-01|8.56534e-01|8.39623e-01|8.08898e-01 1 762604 . G A 64.08 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|||||||||||1|384|1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.299C>T||299||||||1||-1||SNV|HGNC|26211|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 762632 . T A 1.86172e+06 PASS CSQ=A|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs3131948|1|356|1||SNV|HGNC|49377|YES|||||||||||||||0.752|0.4584|0.817|0.8879|0.8718|0.8395||||||||||||0.8879|EAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.271A>T||271|||||rs3131948|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.752|0.4584|0.817|0.8879|0.8718|0.8395||||||||||||0.8879|EAS|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs3131948|1||||SNV||||||||||||||||||0.752|0.4584|0.817|0.8879|0.8718|0.8395||||||||||||0.8879|EAS||||||||||||||||||||||||| 1 762637 . G T 1392.71 PASS CSQ=T|upstream_gene_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||||||||||rs543295788|1|351|1||SNV|HGNC|49377|YES|||||||||||||||0.0014|0.0053|0|0|0|0||||||||||||0.0053|AFR|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|LINC00115|ENSG00000225880|Transcript|ENST00000473798|lincRNA|1/1||ENST00000473798.1:n.266C>A||266|||||rs543295788|1||-1||SNV|HGNC|26211|YES|||||||||||||||0.0014|0.0053|0|0|0|0||||||||||||0.0053|AFR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000086|promoter||||||||||rs543295788|1||||SNV||||||||||||||||||0.0014|0.0053|0|0|0|0||||||||||||0.0053|AFR||||||||||||||||||||||||| 1 777161 . A C 109.8 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10146A>C|||||||rs1038618129|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777175 . G A 85.69 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10132G>A||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777180 . G T 64.41 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10127G>T|||||||rs899904819|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777183 . T C 274.11 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10124T>C||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777184 . G A 92.41 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10123G>A|||||||rs996972020|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777189 . T G 167.07 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10118T>G|||||||rs1029649869|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777203 . C T 286.14 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10104C>T|||||||rs879741358|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs879741358|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777232 . C T 1.63336e+06 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10075C>T|||||||rs112618790|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0669|0.0098|0.0346|0.0754|0.0755|0.1493||||||||||||0.1493|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs112618790|1||||SNV||||||||||||||||||0.0669|0.0098|0.0346|0.0754|0.0755|0.1493||||||||||||0.1493|SAS||||||||||||||||||||||||| 1 777233 . T C 226.97 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10074T>C||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777237 . C A 14024.7 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10070C>A|||||||rs142665498|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0132|0.0484|0.0029|0|0|0||||||||||||0.0484|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs142665498|1||||SNV||||||||||||||||||0.0132|0.0484|0.0029|0|0|0||||||||||||0.0484|AFR||||||||||||||||||||||||| 1 777238 . G A 151.23 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10069G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777242 . G A 540.08 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10065G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777245 . G A 805.44 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10062G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777256 . C G 241.94 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10051C>G||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777269 . G A 1148.81 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10038G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777288 . G A 6284.45 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-10019G>A|||||||rs1046714972|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs1046714972|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777312 . A G 537.93 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9995A>G||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777317 . T G 1764.73 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9990T>G||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777318 . C T,G 34111.5 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9989C>T|||||||rs150580910|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0134|0.0492|0.0029|0|0|0||||||||||||0.0492|AFR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9989C>G|||||||rs150580910|2||1||SNV|HGNC|49377|YES||||||||||||||||0|0|0|0|0.0061||||||||||||0.0061|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs150580910|1||||SNV||||||||||||||||||0.0134|0.0492|0.0029|0|0|0||||||||||||0.0492|AFR|||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs150580910|2||||SNV|||||||||||||||||||0|0|0|0|0.0061||||||||||||0.0061|SAS||||||||||||||||||||||||| 1 777348 . G A 454.93 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9959G>A|||||||rs375849499|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0.002|0|0||||||||||||0.002|EAS|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs375849499|1||||SNV||||||||||||||||||0.0004|0|0|0.002|0|0||||||||||||0.002|EAS||||||||||||||||||||||||| 1 777361 . T C 34377.4 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9946T>C|||||||rs2980318|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0132|0.0484|0.0029|0|0|0||||||||||||0.0484|AFR|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs2980318|1||||SNV||||||||||||||||||0.0132|0.0484|0.0029|0|0|0||||||||||||0.0484|AFR||||||||||||||||||||||||| 1 777379 . G A 4737.91 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9928G>A|||||||rs544107588|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs544107588|1||||SNV||||||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 777390 . C T 385.92 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9917C>T|||||||rs554531412|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0012|0|0|0|0|0.0061||||||||||||0.0061|SAS|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs554531412|1||||SNV||||||||||||||||||0.0012|0|0|0|0|0.0061||||||||||||0.0061|SAS||||||||||||||||||||||||| 1 777392 . T G 1561.98 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9915T>G||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777423 . C T 9969.86 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9884C>T|||||||rs1032098734|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs1032098734|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777431 . G T 240.94 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9876G>T||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777437 . A C 18089.7 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9870A>C|||||||rs540306158|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0018|0|0|0|0.001|0.0082||||||||||||0.0082|SAS|||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs540306158|1||||SNV||||||||||||||||||0.0018|0|0|0|0.001|0.0082||||||||||||0.0082|SAS||||||||||||||||||||||||| 1 777444 . G T 640.95 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9863G>T||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777448 . C T 317.95 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9859C>T||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777449 . G A 659.06 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9858G>A|||||||rs369870837|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs369870837|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777456 . C T 28672.1 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9851C>T|||||||rs183307028|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0158|0.0575|0.0043|0|0|0||||||||||||0.0575|AFR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs183307028|1||||SNV||||||||||||||||||0.0158|0.0575|0.0043|0|0|0||||||||||||0.0575|AFR||||||||||||||||||||||||| 1 777459 . G A 4365.73 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9848G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777481 . G A 353.62 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9826G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777498 . T C 508.17 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9809T>C||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777508 . TGCACGA T 804.09 PASS CSQ=-|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9796_271-9791del||||||||1||1||deletion|HGNC|49377|YES||||||||||||||2||||||||||||||||||||||||||||||||||||||||||||,-|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||deletion||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777512 . C T,* 1931.77 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9795C>T|||||||rs1023116566|1||1||sequence_alteration|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs1023116566|1||||sequence_alteration||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777513 . G A,* 19417.6 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9794G>A|||||||rs6672353|1||1||sequence_alteration|HGNC|49377|YES|||||||||||||||0.0238|0.084|0.0101|0|0.001|0||||||||||||0.084|AFR||||21159730|||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs6672353|1||||sequence_alteration||||||||||||||||||0.0238|0.084|0.0101|0|0.001|0||||||||||||0.084|AFR||||21159730||||||||||||||||||||| 1 777516 . C T 3956.45 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9791C>T|||||||rs546055875|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0044|0.0151|0.0029|0|0|0||||||||||||0.0151|AFR|||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs546055875|1||||SNV||||||||||||||||||0.0044|0.0151|0.0029|0|0|0||||||||||||0.0151|AFR||||||||||||||||||||||||| 1 777558 . G C 1124.62 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9749G>C|||||||rs981591481|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs981591481|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777564 . G A 165.12 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9743G>A|||||||rs1034690249|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs1034690249|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777575 . G A 2801.59 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9732G>A|||||||rs563102246|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0016|0|0|0|0|0.0082||||||||||||0.0082|SAS|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs563102246|1||||SNV||||||||||||||||||0.0016|0|0|0|0|0.0082||||||||||||0.0082|SAS||||||||||||||||||||||||| 1 777578 . C T 407.04 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9729C>T||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777579 . G A 768.05 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9728G>A|||||||rs531871148|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0016|0.0053|0|0|0.001|0||||||||||||0.0053|AFR|||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs531871148|1||||SNV||||||||||||||||||0.0016|0.0053|0|0|0.001|0||||||||||||0.0053|AFR||||||||||||||||||||||||| 1 777581 . A C 39.56 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9726A>C|||||||rs373100579|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region||||||||||rs373100579|1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777582 . C G 146.02 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9725C>G||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777588 . G A 91.61 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9719G>A||||||||1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|regulatory_region_variant|MODIFIER|||RegulatoryFeature|ENSR00000000091|promoter_flanking_region|||||||||||1||||SNV||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777617 . A G 35.07 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9690A>G|||||||rs941268307|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777636 . C T 2369.32 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9671C>T|||||||rs529246218|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0132|0.0484|0.0029|0|0|0||||||||||||0.0484|AFR||||||||||||||||||||||||| 1 777637 . G C 73.26 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9670G>C||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777654 . C G 182.86 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9653C>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777664 . G A 103.99 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9643G>A||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777670 . G A 91.87 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9637G>A||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777679 . A G 32.42 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9628A>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777683 . A G 137.61 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9624A>G|||||||rs529743090|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0012|0.0045|0|0|0|0||||||||||||0.0045|AFR||||||||||||||||||||||||| 1 777690 . C T 1303 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9617C>T|||||||rs547348212|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0008|0|0|0|0.001|0.0031||||||||||||0.0031|SAS||||||||||||||||||||||||| 1 777699 . A G 32.39 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9608A>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 777714 . G T 112.45 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-9593G>T||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 782980 . G A 222.61 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4327G>A|||||||rs1029923293|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 782981 . C T 1.19209e+06 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4326C>T||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 782982 . G A 942.66 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4325G>A|||||||rs375212944|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0010|0|0|0.005|0|0||||||||||||0.005|EAS||||||||||||||||||||||||| 1 783005 . C T 2217.5 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4302C>T|||||||rs977636894|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783015 . TCTCA T 220.93 PASS CSQ=-|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4285_271-4282del|||||||rs956483294|1||1||deletion|HGNC|49377|YES||||||||||||||6|||||||||||||||||||||||||||||||||||||||||||| 1 783042 . AT GT,A 661.85 PASS CSQ=GT|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4265delinsG|||||||rs374744957|1||1||indel|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4264del||||||||2||1||indel|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783049 . T G 244.97 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4258T>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783050 . C T 847.79 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4257C>T|||||||rs564852813|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 783060 . C A 1228.69 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4247C>A||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783070 . A G 1286.89 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4237A>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783071 . C T 454066 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4236C>T|||||||rs142849724|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0106|0.0008|0.0144|0|0.0219|0.0204||||||||||||0.0219|EUR||||||||||||||||||||||||| 1 783090 . C T 308.87 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4217C>T|||||||rs939155795|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783095 . C T 209.93 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4212C>T|||||||rs1046904599|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783096 . G A 1475.83 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4211G>A||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783101 . G T 957.99 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4206G>T||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783107 . G C 354.06 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4200G>C||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783124 . A T,C 1303.77 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4183A>T|||||||rs908611103|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4183A>C||||||||2||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783129 . G A 2373.84 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4178G>A|||||||rs1038373750|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783142 . T G 1091.01 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4165T>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783147 . C T 3588.5 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4160C>T|||||||rs189794196|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0068|0|0.049|0|0|0||||||||||||0.049|AMR||||||||||||||||||||||||| 1 783150 . T C 1002.85 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4157T>C||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783151 . G C 466.02 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4156G>C|||||||rs546438521|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0006|0|0|0.003|0|0||||||||||||0.003|EAS||||||||||||||||||||||||| 1 783174 . C T 2446 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4133C>T|||||||rs182089971|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0|0.0014|0|0|0||||||||||||0.0014|AMR||||||||||||||||||||||||| 1 783175 . G A 8370.51 PASS CSQ=A|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4132G>A|||||||rs147637572|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0076|0.0287|0|0|0|0||||||||||||0.0287|AFR||||||||||||||||||||||||| 1 783180 . C T 113.97 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4127C>T||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783186 . G C 4167.24 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4121G>C|||||||rs141989890|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0040|0.0144|0.0014|0|0|0||||||||||||0.0144|AFR||||||||||||||||||||||||| 1 783193 . G C 237247 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4114G>C|||||||rs145767270|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0028|0|0.0029|0|0.0099|0.002||||||||||||0.0099|EUR||||||||||||||||||||||||| 1 783194 . G T 236345 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4113G>T|||||||rs138555831|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0028|0|0.0029|0|0.0099|0.002||||||||||||0.0099|EUR||||||||||||||||||||||||| 1 783209 . A C 171.1 PASS CSQ=C|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4098A>C|||||||rs187884039|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0004|0|0|0|0.002|0||||||||||||0.002|EUR||||||||||||||||||||||||| 1 783211 . G T 659.9 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4096G>T||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783226 . T G 289.56 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4081T>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 783245 . C T 198.51 PASS CSQ=T|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4062C>T|||||||rs191886010|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0012|0.0045|0|0|0|0||||||||||||0.0045|AFR||||||||||||||||||||||||| 1 783249 . A G 93.19 PASS CSQ=G|intron_variant&non_coding_transcript_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA||2/4|ENST00000445118.2:n.271-4058A>G||||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792185 . C T 130.06 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.3965C>T||3965||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792194 . A C 59.36 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.3974A>C||3974|||||rs1039446391|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792195 . G A 497.41 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.3975G>A||3975|||||rs900805960|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792207 . G A 145.62 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.3987G>A||3987||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792241 . C G 343.15 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4021C>G||4021||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792254 . CAA C 5402.19 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4035_4036del||4035-4036|||||rs567065523|1||1||deletion|HGNC|49377|YES|||||||||||||||0.0076|0.0287|0|0|0|0||||||||||||0.0287|AFR||||||||||||||||||||||||| 1 792263 . A G 8.72865e+06 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4043A>G||4043|||||rs1044922|1||1||SNV|HGNC|49377|YES|||||||||||||||0.7859|0.4531|0.8703|0.8373|0.9722|0.9315||||||||||||0.9722|EUR||||||||||||||||||||||||| 1 792264 . C G 143.61 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4044C>G||4044||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792272 . A G 53.91 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4052A>G||4052||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792276 . A G 317.19 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4056A>G||4056|||||rs958531415|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792280 . CTT C 1537.94 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4061_4062del||4061-4062|||||rs534476969|1||1||deletion|HGNC|49377|YES|||||||||||||||0.0014|0|0|0.0069|0|0||||||||||||0.0069|EAS||||||||||||||||||||||||| 1 792288 . CTG C 346.98 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4069_4070del||4069-4070||||||1||1||deletion|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792299 . T A 79.91 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4079T>A||4079||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792300 . C T 831.03 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4080C>T||4080||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792328 . C T 704.05 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4108C>T||4108|||||rs565979576|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 792346 . C T,A 907.97 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4126C>T||4126|||||rs917352697|1||1||SNV|HGNC|49377|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4126C>A||4126||||||2||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792349 . C T 272.14 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4129C>T||4129|||||rs528738015|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0012|0.003|0.0014|0|0.001|0||||||||||||0.003|AFR||||||||||||||||||||||||| 1 792355 . G A 103.94 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4135G>A||4135||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792368 . C G 340.93 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4148C>G||4148||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792373 . C T 1059.86 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4153C>T||4153|||||rs191879586|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 792379 . T C 3623.24 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4159T>C||4159||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792392 . G A 2509.82 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4172G>A||4172||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792399 . A G 938.09 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4179A>G||4179|||||rs866422103|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792405 . C T 890.97 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4185C>T||4185||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792410 . T C 1216.98 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4190T>C||4190||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792423 . C T 598 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4203C>T||4203||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792441 . T C 682.94 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4221T>C||4221||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792443 . T C 318.99 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4223T>C||4223||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792447 . C T 935.01 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4227C>T||4227||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792448 . G A 4750.64 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4228G>A||4228|||||rs140050759|1||1||SNV|HGNC|49377|YES|||||||||||||||0.0042|0.0151|0|0.001|0|0||||||||||||0.0151|AFR||||||||||||||||||||||||| 1 792453 . A C 530.31 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4233A>C||4233||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792480 . C T 3.50701e+07 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4260C>T||4260|||||rs2905036|1||1||SNV|HGNC|49377|YES|||||||||||||||0.9768|0.9213|0.9899|1|0.995|1||||||||||||1|EAS&SAS||||||||||||||||||||||||| 1 792493 . T C 28016.4 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4273T>C||4273|||||rs559194955|1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792496 . C T 165.27 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4276C>T||4276||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792497 . G A 560.76 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4277G>A||4277||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792506 . TA T 783.99 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4291del||4287||||||1||1||deletion|HGNC|49377|YES||||||||||||||4|||||||||||||||||||||||||||||||||||||||||||| 1 792517 . C T 613.98 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4297C>T||4297||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792523 . A T 332.94 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4303A>T||4303||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792534 . A G 689.5 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4314A>G||4314||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792537 . A C 3490.8 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4317A>C||4317||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 792540 . G C 389.96 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|LINC01128|ENSG00000228794|Transcript|ENST00000445118|lincRNA|5/5||ENST00000445118.2:n.4320G>C||4320||||||1||1||SNV|HGNC|49377|YES|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808659 . T A 119.33 PASS CSQ=A|upstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||1|13|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+833A>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808662 . T C 285.9 PASS CSQ=C|upstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs750555637|1|10|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+830A>G|||||||rs750555637|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808665 . C G 194.95 PASS CSQ=G|upstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||1|7|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+827G>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808672 . G T 174.78 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1G>T||1||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+820C>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808695 . T C 140.85 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.24T>C||24||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+797A>G||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808708 . A G 182.54 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.37A>G||37||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+784T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808710 . T A 2168.76 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.39T>A||39|||||rs188953453|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+782A>T|||||||rs188953453|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 808714 . C T 184.47 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.43C>T||43||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+778G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808723 . C G 289.66 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.52C>G||52|||||rs117906062|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0032|0|0|0.0159|0|0||||||||||||0.0159|EAS|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+769G>C|||||||rs117906062|1||-1||SNV|HGNC|27635||||||||||||||||0.0032|0|0|0.0159|0|0||||||||||||0.0159|EAS||||||||||||||||||||||||| 1 808724 . C G 184.09 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.53C>G||53|||||rs115572781|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0012|0.0045|0|0|0|0||||||||||||0.0045|AFR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+768G>C|||||||rs115572781|1||-1||SNV|HGNC|27635||||||||||||||||0.0012|0.0045|0|0|0|0||||||||||||0.0045|AFR||||||||||||||||||||||||| 1 808725 . G A 3870.11 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.54G>A||54|||||rs890483236|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+767C>T|||||||rs890483236|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808728 . C T 2135.48 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.57C>T||57|||||rs752417910|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+764G>A|||||||rs752417910|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808729 . T A 193.78 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.58T>A||58||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+763A>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808749 . G A 5156.64 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.78G>A||78|||||rs771007361|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+743C>T|||||||rs771007361|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808756 . G T 194.65 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.85G>T||85||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+736C>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808774 . G A 2370.81 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.103G>A||103||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+718C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808788 . G T 2831.32 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.117G>T||117|||||rs980283557|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+704C>A|||||||rs980283557|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808793 . C T 399.07 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.122C>T||122||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+699G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808816 . G A 1875.26 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.145G>A||145|||||rs992755623|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+676C>T|||||||rs992755623|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808837 . G A 270.05 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.166G>A||166|||||rs539786654|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+655C>T|||||||rs539786654|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 808845 . CT C 2739.41 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.175del||175|||||rs907753952|1||1||deletion|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+646del|||||||rs907753952|1||-1||deletion|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808848 . A G 468.58 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.177A>G||177||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+644T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808861 . G A 11912.6 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.190G>A||190|||||rs200253049|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0006|0|0.0029|0|0.001|0||||||||||||0.0029|AMR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+631C>T|||||||rs200253049|1||-1||SNV|HGNC|27635||||||||||||||||0.0006|0|0.0029|0|0.001|0||||||||||||0.0029|AMR||||||||||||||||||||||||| 1 808879 . G A 686.04 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.208G>A||208|||||rs576456810|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+613C>T|||||||rs576456810|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 808888 . A G 107.19 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.217A>G||217||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+604T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808898 . C T 2056.57 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.227C>T||227||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+594G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808899 . G A 1932.48 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.228G>A||228|||||rs373579601|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0010|0|0|0.005|0|0||||||||||||0.005|EAS|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+593C>T|||||||rs373579601|1||-1||SNV|HGNC|27635||||||||||||||||0.0010|0|0|0.005|0|0||||||||||||0.005|EAS||||||||||||||||||||||||| 1 808909 . C T 1423.8 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.238C>T||238|||||rs555794208|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0008|0.0023|0|0|0|0.001||||||||||||0.0023|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+583G>A|||||||rs555794208|1||-1||SNV|HGNC|27635||||||||||||||||0.0008|0.0023|0|0|0|0.001||||||||||||0.0023|AFR||||||||||||||||||||||||| 1 808922 . G A 7.2667e+07 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.251G>A||251||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+570C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808928 . C T 5.38775e+07 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.257C>T||257||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+564G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808929 . G A 5570.3 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.258G>A||258|||||rs564384687|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+563C>T|||||||rs564384687|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 808938 . C T 177.65 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.267C>T||267||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+554G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808957 . C T 1043.58 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.286C>T||286||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+535G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808962 . C T 2656.87 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.291C>T||291||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+530G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 808984 . A G 22108.2 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.313A>G||313|||||rs200611786|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+508T>C|||||||rs200611786|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 808998 . A T 635.5 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.327A>T||327||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+494T>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809001 . G A 27506.5 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.330G>A||330|||||rs184951212|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+491C>T|||||||rs184951212|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 809006 . C T 208.16 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.335C>T||335|||||rs1001283481|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+486G>A|||||||rs1001283481|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809007 . G A 82.7 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.336G>A||336||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+485C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809017 . A G 1079.73 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.346A>G||346||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+475T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809022 . A G 600.3 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.351A>G||351|||||rs568129031|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+470T>C|||||||rs568129031|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 809043 . C T 11716.2 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.372C>T||372|||||rs201498940|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+449G>A|||||||rs201498940|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 809091 . A G 887.74 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.420A>G||420||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+401T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809097 . G A 1376.98 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.426G>A||426||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+395C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809107 . C T 56.74 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.436C>T||436||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+385G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809115 . C T 442.04 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.444C>T||444||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+377G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809116 . G A 49.38 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.445G>A||445|||||rs907549298|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+376C>T|||||||rs907549298|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809123 . G A,T 908.03 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.452G>A||452|||||rs61768216|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0054|0.0091|0|0.0149|0|0||||||||||||0.0149|EAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.452G>T||452|||||rs61768216|2||1||SNV|HGNC|32337|YES||||||||||||||||0|0|0|0.001|0||||||||||||0.001|EUR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+369C>T|||||||rs61768216|1||-1||SNV|HGNC|27635||||||||||||||||0.0054|0.0091|0|0.0149|0|0||||||||||||0.0149|EAS|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+369C>A|||||||rs61768216|2||-1||SNV|HGNC|27635|||||||||||||||||0|0|0|0.001|0||||||||||||0.001|EUR||||||||||||||||||||||||| 1 809136 . G A 93.5 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.465G>A||465||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+356C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809146 . G A 926.38 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.475G>A||475|||||rs973339577|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+346C>T|||||||rs973339577|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809150 . G T 281.41 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.479G>T||479||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+342C>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809157 . G A 999.37 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.486G>A||486|||||rs569979246|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0004|0.0008|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+335C>T|||||||rs569979246|1||-1||SNV|HGNC|27635||||||||||||||||0.0004|0.0008|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 809171 . G A 63.78 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.500G>A||500|||||rs535825011|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0084|0.0174|0.0014|0|0.002|0.0164||||||||||||0.0174|AFR|||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+321C>T|||||||rs535825011|1||-1||SNV|HGNC|27635||||||||||||||||0.0084|0.0174|0.0014|0|0.002|0.0164||||||||||||0.0174|AFR||||||||||||||||||||||||| 1 809178 . C T 6628.66 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.507C>T||507|||||rs189512519|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0036|0.0008|0|0.0159|0.001|0||||||||||||0.0159|EAS|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+314G>A|||||||rs189512519|1||-1||SNV|HGNC|27635||||||||||||||||0.0036|0.0008|0|0.0159|0.001|0||||||||||||0.0159|EAS||||||||||||||||||||||||| 1 809213 . G A 374.3 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.542G>A||542||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+279C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809221 . A G 1752.32 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.550A>G||550||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+271T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809237 . C G 8954.08 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.566C>G||566|||||rs200657693|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+255G>C|||||||rs200657693|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809238 . C T 2810.04 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.567C>T||567|||||rs112738735|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0070|0.0144|0|0.0159|0|0||||||||||||0.0159|EAS|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+254G>A|||||||rs112738735|1||-1||SNV|HGNC|27635||||||||||||||||0.0070|0.0144|0|0.0159|0|0||||||||||||0.0159|EAS||||||||||||||||||||||||| 1 809242 . C T 85.14 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.571C>T||571||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+250G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809248 . CTGTGGCTGAGCTCACCCAGCAGA C 708.18 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.581_603del||578-600||||||1||1||deletion|HGNC|32337|YES||||||||||||||3||||||||||||||||||||||||||||||||||||||||||||,-|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+221_1202+243del||||||||1||-1||deletion|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809261 . C T,* 3806.44 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.590C>T||590|||||rs202083165|1||1||sequence_alteration|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+231G>A|||||||rs202083165|1||-1||sequence_alteration|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809268 . C T,* 2131.02 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.597C>T||597||||||1||1||sequence_alteration|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+224G>A||||||||1||-1||sequence_alteration|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809273 . G A 47.74 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.602G>A||602||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+219C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809301 . C T 10250.8 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.630C>T||630|||||rs878944056|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+191G>A|||||||rs878944056|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809319 . C T 49387.5 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.648C>T||648||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+173G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809326 . T G 4226.73 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.655T>G||655||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+166A>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809329 . C T 3358.42 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.658C>T||658||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+163G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809330 . G A 116.78 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.659G>A||659|||||rs905357773|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+162C>T|||||||rs905357773|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809346 . C A 194.84 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.675C>A||675||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+146G>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809347 . A G 195.29 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.676A>G||676||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+145T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809351 . T G 342.35 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.680T>G||680||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+141A>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809352 . C T 1926.47 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.681C>T||681||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+140G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809353 . G A 113.93 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.682G>A||682||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+139C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809379 . C T 252.87 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.708C>T||708|||||rs778339940|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+113G>A|||||||rs778339940|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809385 . T A 2190.85 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.714T>A||714|||||rs565321068|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+107A>T|||||||rs565321068|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809407 . G A 149.3 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.736G>A||736||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+85C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809427 . C T 60.54 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.756C>T||756||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+65G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809430 . C A 21598.4 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.759C>A||759|||||rs1035202811|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+62G>T|||||||rs1035202811|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809434 . A G 175.25 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.763A>G||763||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+58T>C||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809439 . T A 883.87 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.768T>A||768||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+53A>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809446 . C T 3044.68 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.775C>T||775||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+46G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809447 . T A 507.57 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.776T>A||776||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+45A>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809451 . G A 262.5 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.780G>A||780||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+41C>T||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809454 . T C 703.71 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.783T>C||783||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+38A>G||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809464 . C T 139.69 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.793C>T||793||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+28G>A||||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809469 . C T 218.7 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.798C>T||798|||||rs189619677|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0008|0.003|0|0|0|0||||||||||||0.003|AFR|||||||||||||||||||||||||,T|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+23G>A|||||||rs189619677|1||-1||SNV|HGNC|27635||||||||||||||||0.0008|0.003|0|0|0|0||||||||||||0.003|AFR||||||||||||||||||||||||| 1 809470 . G A 1242.54 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.799G>A||799|||||rs539074120|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|intron_variant&non_coding_transcript_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA||2/2|ENST00000446136.1:n.1202+22C>T|||||||rs539074120|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809510 . G A 11063.2 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.839G>A||839||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1184C>T||1184||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809533 . G A 14058.6 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.862G>A||862|||||rs181950135|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1161C>T||1161|||||rs181950135|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809534 . T G 1636.32 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.863T>G||863||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1160A>C||1160||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809535 . G A 5217.7 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.864G>A||864||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1159C>T||1159||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809558 . G A 134.19 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.887G>A||887||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1136C>T||1136||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809563 . G T 19883.9 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.892G>T||892|||||rs759934744|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1131C>A||1131|||||rs759934744|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809565 . C T 701.04 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.894C>T||894|||||rs746381843|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1129G>A||1129|||||rs746381843|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809572 . C T 168.6 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.901C>T||901||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1122G>A||1122||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809582 . T C 20520 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.911T>C||911|||||rs112115309|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0068|0.0136|0|0.0159|0|0||||||||||||0.0159|EAS|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1112A>G||1112|||||rs112115309|1||-1||SNV|HGNC|27635||||||||||||||||0.0068|0.0136|0|0.0159|0|0||||||||||||0.0159|EAS||||||||||||||||||||||||| 1 809590 . C T 175.74 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.919C>T||919||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1104G>A||1104||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809591 . G A 3265.57 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.920G>A||920||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1103C>T||1103||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809594 . C T 97.19 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.923C>T||923|||||rs905407705|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1100G>A||1100|||||rs905407705|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809595 . G A 72.55 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.924G>A||924||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1099C>T||1099||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809596 . A G 106.25 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.925A>G||925|||||rs938290087|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1098T>C||1098|||||rs938290087|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809602 . T A 1956.66 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.931T>A||931||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1092A>T||1092||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809615 . A C 423.85 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.944A>C||944|||||rs140893448|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1079T>G||1079|||||rs140893448|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 809621 . C T 16092.8 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.950C>T||950|||||rs1055059087|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1073G>A||1073|||||rs1055059087|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809622 . G A 362.49 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.951G>A||951|||||rs147953396|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0032|0|0|0.0159|0|0||||||||||||0.0159|EAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1072C>T||1072|||||rs147953396|1||-1||SNV|HGNC|27635||||||||||||||||0.0032|0|0|0.0159|0|0||||||||||||0.0159|EAS||||||||||||||||||||||||| 1 809624 . G A 2062.42 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.953G>A||953||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1070C>T||1070||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809628 . G A 3899.41 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.957G>A||957|||||rs141590546|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0028|0.0053|0.0101|0|0|0||||||||||||0.0101|AMR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1066C>T||1066|||||rs141590546|1||-1||SNV|HGNC|27635||||||||||||||||0.0028|0.0053|0.0101|0|0|0||||||||||||0.0101|AMR||||||||||||||||||||||||| 1 809638 . T A 200 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.967T>A||967||||||1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1056A>T||1056||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809680 . C T 2129.11 PASS CSQ=T|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1009C>T||1009|||||rs994472305|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1014G>A||1014|||||rs994472305|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809681 . G A 24251.6 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1010G>A||1010|||||rs76484423|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1013C>T||1013|||||rs76484423|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809687 . G C,A 32865.1 PASS CSQ=C|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1016G>C||1016|||||rs80351405|1||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1016G>A||1016||||||2||1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1007C>G||1007|||||rs80351405|1||-1||SNV|HGNC|27635|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1007C>T||1007||||||2||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809690 . G A 1727.98 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1019G>A||1019|||||rs535428868|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0012|0.0045|0|0|0|0||||||||||||0.0045|AFR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.1004C>T||1004|||||rs535428868|1||-1||SNV|HGNC|27635||||||||||||||||0.0012|0.0045|0|0|0|0||||||||||||0.0045|AFR||||||||||||||||||||||||| 1 809700 . G A 62297.7 PASS CSQ=A|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1029G>A||1029|||||rs114598413|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0298|0.1059|0.0086|0|0.003|0||||||||||||0.1059|AFR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.994C>T||994|||||rs114598413|1||-1||SNV|HGNC|27635||||||||||||||||0.0298|0.1059|0.0086|0|0.003|0||||||||||||0.1059|AFR||||||||||||||||||||||||| 1 809707 . A G 279.6 PASS CSQ=G|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1036A>G||1036|||||rs565893356|1||1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.987T>C||987|||||rs565893356|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 809711 . TG T 2403.02 PASS CSQ=-|non_coding_transcript_exon_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|1/1||ENST00000415481.1:n.1041del||1041|||||rs772565985|1||1||deletion|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.982del||982|||||rs772565985|1||-1||deletion|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809732 . T C 2947.42 PASS CSQ=C|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs147199422|1|3|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.962A>G||962|||||rs147199422|1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809741 . T A 35.63 PASS CSQ=A|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs535041283|1|12|1||SNV|HGNC|32337|YES|||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.953A>T||953|||||rs535041283|1||-1||SNV|HGNC|27635||||||||||||||||0.0002|0.0008|0|0|0|0||||||||||||0.0008|AFR||||||||||||||||||||||||| 1 809744 . A G 1401.17 PASS CSQ=G|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||1|15|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,G|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.950T>C||950||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809752 . G C,GT 8296.97 PASS CSQ=C|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs765508009|1|23|1||indel|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,GT|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||2|23|1||indel|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.942C>G||942|||||rs765508009|1||-1||indel|HGNC|27635|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,GT|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.941_942insA||942||||||2||-1||indel|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809756 . G A 4354.5 PASS CSQ=A|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs117047892|1|27|1||SNV|HGNC|32337|YES|||||||||||||||0.0052|0.0076|0|0.0159|0|0||||||||||||0.0159|EAS|||||||||||||||||||||||||,A|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.938C>T||938|||||rs117047892|1||-1||SNV|HGNC|27635||||||||||||||||0.0052|0.0076|0|0.0159|0|0||||||||||||0.0159|EAS||||||||||||||||||||||||| 1 809761 . AGC A 236.12 PASS CSQ=-|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs979370165|1|33|1||deletion|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,-|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.931_932del||931-932|||||rs979370165|1||-1||deletion|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809763 . C *,T 1888.18 PASS CSQ=T|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene||||||||||rs577749905|2|34|1||sequence_alteration|HGNC|32337|YES|||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS|||||||||||||||||||||||||,T|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.931G>A||931|||||rs577749905|2||-1||sequence_alteration|HGNC|27635||||||||||||||||0.0002|0|0|0|0|0.001||||||||||||0.001|SAS||||||||||||||||||||||||| 1 809764 . G C 1669.09 PASS CSQ=C|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||1|35|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.930C>G||930||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809766 . G GCA 243.26 PASS CSQ=CA|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||1|37|1||insertion|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,CA|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.927_928insTG||927-928||||||1||-1||insertion|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 809768 . A C 2167.1 PASS CSQ=C|downstream_gene_variant|MODIFIER|TUBB8P11|ENSG00000234711|Transcript|ENST00000415481|unprocessed_pseudogene|||||||||||1|39|1||SNV|HGNC|32337|YES||||||||||||||||||||||||||||||||||||||||||||||||||||||||||,C|non_coding_transcript_exon_variant|MODIFIER|FAM41C|ENSG00000230368|Transcript|ENST00000446136|lincRNA|2/3||ENST00000446136.1:n.926T>G||926||||||1||-1||SNV|HGNC|27635||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860416 . G A 616869 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs61464428|1|702|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04||||||||0.5114|0.2564|0.5951|0.4464|0.7763|0.591||||||||||||0.7763|EUR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs61464428|1|848|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||0.5114|0.2564|0.5951|0.4464|0.7763|0.591||||||||||||0.7763|EUR||||||||||||||||||||||||| 1 860417 . G T 38.51 PASS CSQ=T|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|||||||||||1|701|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|847|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860431 . G T 12736.1 PASS CSQ=T|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|||||||||||1|687|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|833|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860461 . G A 822612 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs57465118|1|657|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04||||||||0.6823|0.3404|0.83|0.5526|0.9742|0.8732||||||||||||0.9742|EUR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs57465118|1|803|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||0.6823|0.3404|0.83|0.5526|0.9742|0.8732||||||||||||0.9742|EUR||||||||||||||||||||||||| 1 860498 . C G 61631.5 PASS CSQ=G|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs919828183|1|620|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs919828183|1|766|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860504 . G A 2021.16 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs78033073|1|614|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04||||||||0.0551|0.028|0.1023|0.1379|0.002|0.0276||||||||||||0.1379|EAS|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs78033073|1|760|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||0.0551|0.028|0.1023|0.1379|0.002|0.0276||||||||||||0.1379|EAS||||||||||||||||||||||||| 1 860511 . C T 66.9 PASS CSQ=T|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs1052797345|1|607|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs1052797345|1|753|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860521 . C A 1.14406e+06 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs57924093|1|597|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04||||||||0.6795|0.3298|0.8314|0.5476|0.9751|0.8763||||||||||||0.9751|EUR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs57924093|1|743|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||0.6795|0.3298|0.8314|0.5476|0.9751|0.8763||||||||||||0.9751|EUR||||||||||||||||||||||||| 1 860564 . C T 149.61 PASS CSQ=T|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|||||||||||1|554|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|700|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860604 . G A 37.35 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs961481098|1|514|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs961481098|1|660|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860607 . A G 302.91 PASS CSQ=G|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs974039449|1|511|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,G|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs974039449|1|657|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860637 . AG A 176.75 PASS CSQ=-|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs779931996|1|480|1||deletion|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,-|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs779931996|1|626|-1||deletion|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860684 . G A 77.88 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|||||||||||1|434|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|580|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 860688 . G A 1.42925e+06 PASS CSQ=A|upstream_gene_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||||||||||rs60837925|1|430|1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04||||||||0.5052|0.2345|0.5937|0.4464|0.7763|0.59||||||||||||0.7763|EUR|||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs60837925|1|576|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||0.5052|0.2345|0.5937|0.4464|0.7763|0.59||||||||||||0.7763|EUR||||||||||||||||||||||||| 1 861172 . C T 44.68 PASS CSQ=T|5_prime_UTR_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|1/14||ENST00000342066.3:c.-29C>T||55||||||1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|92|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 861177 . C A 271.27 PASS CSQ=A|5_prime_UTR_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|1/14||ENST00000342066.3:c.-24C>A||60||||||1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|87|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 861178 . G A 253.29 PASS CSQ=A|splice_region_variant&5_prime_UTR_variant|LOW|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding|1/14||ENST00000342066.3:c.-23G>A||61||||||1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|86|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 861196 . G C 167.05 PASS CSQ=C|intron_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||1/13|ENST00000342066.3:c.-21+16G>C||||||||1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,C|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|68|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 861209 . T A 120.43 PASS CSQ=A|intron_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||1/13|ENST00000342066.3:c.-21+29T>A||||||||1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,A|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|55|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 861211 . C T 537.5 PASS CSQ=T|intron_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||1/13|ENST00000342066.3:c.-21+31C>T||||||||1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding|||||||||||1|53|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| 1 861213 . C T 69.71 PASS CSQ=T|intron_variant|MODIFIER|SAMD11|ENSG00000187634|Transcript|ENST00000342066|protein_coding||1/13|ENST00000342066.3:c.-21+33C>T|||||||rs965244502|1||1||SNV|HGNC|28706|YES|||CCDS2.2|ENSP00000342313|Q96NU1|Q5SV95&I7FV93&A6PWC8|UPI0000D61E04|||||||||||||||||||||||||||||||||||||||||||||||||||,T|downstream_gene_variant|MODIFIER|AL645608.1|ENSG00000268179|Transcript|ENST00000598827|protein_coding||||||||||rs965244502|1|51|-1||SNV|Clone_based_ensembl_gene||YES||||ENSP00000471152||M0R0C9|UPI0000D61E05||||||||||||||||||||||||||||||||||||||||||||||||||| bcftools-1.21/test/split.1.1.out000066400000000000000000000007741467060157400164330ustar00rootroot00000000000000A1.vcf A1 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 A2.vcf A2 22 10 . C A . . . GT 0/1 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 A3.vcf A3 22 10 . C A . . . GT 0/0 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 B1.vcf B1 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 B2.vcf B2 22 10 . C A . . . GT 0/0 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 C.vcf C 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.2.out000066400000000000000000000003711467060157400164250ustar00rootroot00000000000000A.vcf A 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 B.vcf B 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 C.vcf C 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.3.out000066400000000000000000000004521467060157400164260ustar00rootroot00000000000000a3.vcf a3 a2 a1 22 10 . C A . . . GT 0/0 0/1 ./. 22 22 . A C . . . GT 0/0 0/0 0/0 22 23 . C A . . . GT 0/0 0/0 0/1 b2.vcf b2 b1 22 10 . C A . . . GT 0/0 ./. 22 22 . A C . . . GT 0/0 0/0 22 23 . C A . . . GT 0/0 0/1 c.vcf c 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.4.out000066400000000000000000000000761467060157400164310ustar00rootroot00000000000000a3.vcf a3 a2 a1 b2.vcf b2 b1 c.vcf c 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.5.out000066400000000000000000000002351467060157400164270ustar00rootroot00000000000000a3.vcf a3 a2 a1 22 10 . C A . . . GT 0/0 0/1 ./. 22 23 . C A . . . GT 0/0 0/0 0/1 b2.vcf b2 b1 22 23 . C A . . . GT 0/0 0/1 c.vcf c 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.6.out000066400000000000000000000002471467060157400164330ustar00rootroot00000000000000file1.vcf a3 a2 a1 22 10 . C A . . . GT 0/0 0/1 ./. 22 23 . C A . . . GT 0/0 0/0 0/1 file2.vcf b2 b1 22 23 . C A . . . GT 0/0 0/1 file3.vcf c 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.7.out000066400000000000000000000005751467060157400164400ustar00rootroot00000000000000A.vcf a3 C 22 10 . C A . . . GT 0/0 ./. 22 22 . A C . . . GT 0/0 0/0 22 23 . C A . . . GT 0/0 1/0 A1.vcf A1 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 A2.vcf a2 22 10 . C A . . . GT 0/1 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 B.vcf b1 b2 C 22 10 . C A . . . GT ./. 0/0 ./. 22 22 . A C . . . GT 0/0 0/0 0/0 22 23 . C A . . . GT 0/1 0/0 1/0 bcftools-1.21/test/split.1.8.out000066400000000000000000000002521467060157400164310ustar00rootroot00000000000000file1.vcf a3 a2 a1 22 10 . C A . . . GT 0/0 0/1 ./. 22 23 . C A . . . GT 0/0 0/0 0/1 file2.vcf.gz b2 b1 22 23 . C A . . . GT 0/0 0/1 file3.bcf c 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.1.vcf000066400000000000000000000005171467060157400162360ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A1 A2 A3 B1 B2 C 22 10 . C A . . . GT ./. 0/1 0/0 ./. 0/0 ./. 22 22 . A C . . . GT 0/0 0/0 0/0 0/0 0/0 0/0 22 23 . C A . . . GT 0/1 0/0 0/0 0/1 0/0 1/0 bcftools-1.21/test/split.2.1.out000066400000000000000000000010241467060157400164210ustar00rootroot00000000000000A1_A1-1.vcf A1/A1-1 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 A1_A1-2.vcf A1:A1 22 10 . C A . . . GT 0/0 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 A1_A1.vcf A1\A1 22 10 . C A . . . GT 0/1 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 B1.vcf B1 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/1 B2.vcf B2 22 10 . C A . . . GT 0/0 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 0/0 C.vcf C 22 10 . C A . . . GT ./. 22 22 . A C . . . GT 0/0 22 23 . C A . . . GT 1/0 bcftools-1.21/test/split.2.vcf000066400000000000000000000005321467060157400162340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fasta ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A1/A1-1 A1\A1 A1:A1 B1 B2 C 22 10 . C A . . . GT ./. 0/1 0/0 ./. 0/0 ./. 22 22 . A C . . . GT 0/0 0/0 0/0 0/0 0/0 0/0 22 23 . C A . . . GT 0/1 0/0 0/0 0/1 0/0 1/0 bcftools-1.21/test/split.grp.1.1.txt000066400000000000000000000000641467060157400172220ustar00rootroot00000000000000A1 A2 a2 A3 a3 A B1 b1 B B2 b2 B C - A,B bcftools-1.21/test/split.smpl.1.2.txt000066400000000000000000000000301467060157400173770ustar00rootroot00000000000000A1 A B1 B C C bcftools-1.21/test/split.smpl.1.3.txt000066400000000000000000000000651467060157400174100ustar00rootroot00000000000000A3,A2,A1 a3,a2,a1 B2,B1 b2,b1 C c bcftools-1.21/test/split.smpl.1.4.txt000066400000000000000000000001321467060157400174040ustar00rootroot00000000000000A3,A2,A1 a3,a2,a1 file1 B2,B1 b2,b1 file2 C c file3 bcftools-1.21/test/stats.B.chk000066400000000000000000000036051467060157400162520ustar00rootroot00000000000000SN 0 number of samples: 3 SN 1 number of samples: 3 SN 0 number of records: 0 SN 0 number of no-ALTs: 0 SN 0 number of SNPs: 0 SN 0 number of MNPs: 0 SN 0 number of indels: 0 SN 0 number of others: 0 SN 0 number of multiallelic sites: 0 SN 0 number of multiallelic SNP sites: 0 SN 1 number of records: 0 SN 1 number of no-ALTs: 0 SN 1 number of SNPs: 0 SN 1 number of MNPs: 0 SN 1 number of indels: 0 SN 1 number of others: 0 SN 1 number of multiallelic sites: 0 SN 1 number of multiallelic SNP sites: 0 SN 2 number of records: 4 SN 2 number of no-ALTs: 0 SN 2 number of SNPs: 4 SN 2 number of MNPs: 0 SN 2 number of indels: 0 SN 2 number of others: 0 SN 2 number of multiallelic sites: 0 SN 2 number of multiallelic SNP sites: 0 TSTV 0 0 0 0.00 0 0 0.00 TSTV 1 0 0 0.00 0 0 0.00 TSTV 2 3 1 3.00 3 1 3.00 SiS 0 1 0 0 0 0 0 0 0 SiS 1 1 0 0 0 0 0 0 0 SiS 2 1 1 0 1 0 0 0 0 AF 2 0.000000 1 0 1 0 0 0 0 AF 2 0.490000 3 3 0 0 0 0 0 QUAL 2 . 4 3 1 0 ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 0 ST 0 C>G 0 ST 0 C>T 0 ST 0 G>A 0 ST 0 G>C 0 ST 0 G>T 0 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 ST 1 A>C 0 ST 1 A>G 0 ST 1 A>T 0 ST 1 C>A 0 ST 1 C>G 0 ST 1 C>T 0 ST 1 G>A 0 ST 1 G>C 0 ST 1 G>T 0 ST 1 T>A 0 ST 1 T>C 0 ST 1 T>G 0 ST 2 A>C 0 ST 2 A>G 0 ST 2 A>T 0 ST 2 C>A 0 ST 2 C>G 0 ST 2 C>T 0 ST 2 G>A 3 ST 2 G>C 0 ST 2 G>T 1 ST 2 T>A 0 ST 2 T>C 0 ST 2 T>G 0 SN 2 number of samples: 1 GCsAF 2 0.490000 0 1 0 0 2 0 0 3 NRDs 2 75.000000 0.000000 75.000000 0.000000 NRDi 2 0.000000 0.000000 0.000000 0.000000 GCsS 2 B 75.000 0 1 0 0 3 0 0 GCiS 2 B 0.000 0 0 0 0 0 0 0 GCTs B 0 0 0 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GCTi B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PSC 0 B 0 0 0 0 0 0 0.0 0 0 0 0 PSC 1 B 0 0 0 0 0 0 0.0 0 0 0 0 PSC 2 B 0 0 4 3 1 0 0.0 4 0 0 0 PSI 0 B 0 0 0 0.00 0 0 0 0 PSI 1 B 0 0 0 0.00 0 0 0 0 PSI 2 B 0 0 0 0.00 0 0 0 0 HWE 2 0.000000 1 0.990000 0.990000 0.990000 HWE 2 0.490000 3 0.990000 0.990000 0.990000 bcftools-1.21/test/stats.a.vcf000066400000000000000000000006401467060157400163160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 1000 . G A . PASS . GT 0/0 0/1 1/1 1 1001 . G A . PASS . GT 0/0 0/1 1/1 1 1002 . G A . PASS . GT 0/0 0/1 1/1 1 1003 . G T . PASS . GT 0/0 0/1 0/0 bcftools-1.21/test/stats.b.vcf000066400000000000000000000006401467060157400163170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 1000 . G A . PASS . GT 0/1 0/0 0/0 1 1001 . G A . PASS . GT 0/0 0/0 0/0 1 1002 . G A . PASS . GT 0/0 0/1 0/0 1 1003 . G T . PASS . GT 1/1 1/1 1/1 bcftools-1.21/test/stats.chk000066400000000000000000000051241467060157400160700ustar00rootroot00000000000000SN 0 number of samples: 3 SN 1 number of samples: 3 SN 0 number of records: 0 SN 0 number of no-ALTs: 0 SN 0 number of SNPs: 0 SN 0 number of MNPs: 0 SN 0 number of indels: 0 SN 0 number of others: 0 SN 0 number of multiallelic sites: 0 SN 0 number of multiallelic SNP sites: 0 SN 1 number of records: 0 SN 1 number of no-ALTs: 0 SN 1 number of SNPs: 0 SN 1 number of MNPs: 0 SN 1 number of indels: 0 SN 1 number of others: 0 SN 1 number of multiallelic sites: 0 SN 1 number of multiallelic SNP sites: 0 SN 2 number of records: 4 SN 2 number of no-ALTs: 0 SN 2 number of SNPs: 4 SN 2 number of MNPs: 0 SN 2 number of indels: 0 SN 2 number of others: 0 SN 2 number of multiallelic sites: 0 SN 2 number of multiallelic SNP sites: 0 TSTV 0 0 0 0.00 0 0 0.00 TSTV 1 0 0 0.00 0 0 0.00 TSTV 2 3 1 3.00 3 1 3.00 SiS 0 1 0 0 0 0 0 0 0 SiS 1 1 0 0 0 0 0 0 0 SiS 2 1 1 0 1 0 0 0 0 AF 2 0.000000 1 0 1 0 0 0 0 AF 2 0.490000 3 3 0 0 0 0 0 QUAL 2 . 4 3 1 0 ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 0 ST 0 C>G 0 ST 0 C>T 0 ST 0 G>A 0 ST 0 G>C 0 ST 0 G>T 0 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 ST 1 A>C 0 ST 1 A>G 0 ST 1 A>T 0 ST 1 C>A 0 ST 1 C>G 0 ST 1 C>T 0 ST 1 G>A 0 ST 1 G>C 0 ST 1 G>T 0 ST 1 T>A 0 ST 1 T>C 0 ST 1 T>G 0 ST 2 A>C 0 ST 2 A>G 0 ST 2 A>T 0 ST 2 C>A 0 ST 2 C>G 0 ST 2 C>T 0 ST 2 G>A 3 ST 2 G>C 0 ST 2 G>T 1 ST 2 T>A 0 ST 2 T>C 0 ST 2 T>G 0 SN 2 number of samples: 3 GCsAF 2 0.490000 2 1 0 1 2 3 0.107143 9 NRDs 2 90.000000 60.000000 75.000000 100.000000 NRDi 2 0.000000 0.000000 0.000000 0.000000 GCsS 2 A 100.000 2 0 0 2 0 0 0 GCsS 2 B 75.000 0 1 0 0 3 0 0 GCsS 2 C 100.000 0 0 0 1 0 3 1.000000 GCiS 2 A 0.000 0 0 0 0 0 0 0 GCiS 2 B 0.000 0 0 0 0 0 0 0 GCiS 2 C 0.000 0 0 0 0 0 0 0 GCTs A 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GCTs B 0 0 0 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GCTs C 0 0 1 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GCTi A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GCTi B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 GCTi C 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PSC 0 A 0 0 0 0 0 0 0.0 0 0 0 0 PSC 0 B 0 0 0 0 0 0 0.0 0 0 0 0 PSC 0 C 0 0 0 0 0 0 0.0 0 0 0 0 PSC 1 A 0 0 0 0 0 0 0.0 0 0 0 0 PSC 1 B 0 0 0 0 0 0 0.0 0 0 0 0 PSC 1 C 0 0 0 0 0 0 0.0 0 0 0 0 PSC 2 A 4 0 0 0 0 0 0.0 0 0 0 0 PSC 2 B 0 0 4 3 1 0 0.0 1 0 0 0 PSC 2 C 1 3 0 3 0 0 0.0 0 0 0 0 PSI 0 A 0 0 0 0.00 0 0 0 0 PSI 0 B 0 0 0 0.00 0 0 0 0 PSI 0 C 0 0 0 0.00 0 0 0 0 PSI 1 A 0 0 0 0.00 0 0 0 0 PSI 1 B 0 0 0 0.00 0 0 0 0 PSI 1 C 0 0 0 0.00 0 0 0 0 PSI 2 A 0 0 0 0.00 0 0 0 0 PSI 2 B 0 0 0 0.00 0 0 0 0 PSI 2 C 0 0 0 0.00 0 0 0 0 HWE 2 0.000000 1 0.330000 0.330000 0.330000 HWE 2 0.490000 3 0.330000 0.330000 0.330000 bcftools-1.21/test/stats.counts.2.chk000066400000000000000000000015111467060157400175360ustar00rootroot00000000000000SN 0 number of samples: 3 SN 0 number of records: 5 SN 0 number of no-ALTs: 0 SN 0 number of SNPs: 5 SN 0 number of MNPs: 0 SN 0 number of indels: 0 SN 0 number of others: 0 SN 0 number of multiallelic sites: 2 SN 0 number of multiallelic SNP sites: 2 TSTV 0 3 4 0.75 2 3 0.67 SiS 0 1 2 1 1 0 0 0 0 AF 0 0.000000 3 1 2 0 0 0 0 AF 0 0.330000 2 1 1 0 0 0 0 AF 0 0.490000 2 1 1 0 0 0 0 QUAL 0 . 5 2 3 0 ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 2 ST 0 C>G 1 ST 0 C>T 1 ST 0 G>A 2 ST 0 G>C 1 ST 0 G>T 0 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 PSC 0 A 4 0 0 0 0 0 0.0 0 0 0 1 PSC 0 B 0 1 2 2 2 0 0.0 0 2 0 0 PSC 0 C 0 3 0 2 1 0 0.0 0 0 1 1 PSI 0 A 0 0 0 0.00 0 0 0 0 PSI 0 B 0 0 0 0.00 0 0 0 0 PSI 0 C 0 0 0 0.00 0 0 0 0 HWE 0 0.000000 2 0.000000 0.000000 0.000000 HWE 0 0.330000 1 0.000000 0.000000 0.000000 HWE 0 0.490000 1 0.330000 0.330000 0.330000 bcftools-1.21/test/stats.counts.chk000066400000000000000000000015311467060157400174000ustar00rootroot00000000000000SN 0 number of samples: 3 SN 0 number of records: 12 SN 0 number of no-ALTs: 2 SN 0 number of SNPs: 7 SN 0 number of MNPs: 2 SN 0 number of indels: 1 SN 0 number of others: 2 SN 0 number of multiallelic sites: 4 SN 0 number of multiallelic SNP sites: 2 TSTV 0 4 4 1.00 3 3 1.00 SiS 0 1 2 1 1 1 0 0 1 AF 0 0.000000 3 1 2 1 0 0 1 AF 0 0.330000 2 1 1 0 0 0 0 AF 0 0.490000 3 2 1 0 0 0 0 QUAL 0 . 6 3 3 1 IDD 0 1 1 0 . ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 2 ST 0 C>G 1 ST 0 C>T 1 ST 0 G>A 3 ST 0 G>C 1 ST 0 G>T 0 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 PSC 0 A 11 0 0 0 0 0 0.0 0 0 0 1 PSC 0 B 1 1 4 3 2 1 0.0 0 2 0 0 PSC 0 C 1 5 0 3 1 0 0.0 0 0 1 1 PSI 0 A 0 0 0 0.00 0 0 0 0 PSI 0 B 0 0 0 0.00 1 0 0 0 PSI 0 C 0 0 0 0.00 0 0 0 0 HWE 0 0.000000 2 0.000000 0.000000 0.000000 HWE 0 0.330000 1 0.000000 0.000000 0.000000 HWE 0 0.490000 7 0.330000 0.330000 0.330000 bcftools-1.21/test/stats.counts.vcf000066400000000000000000000014551467060157400174160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##ALT= ##FORMAT= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C 1 1000 . G A . PASS . GT 0/0 0/1 1/1 1 1001 . G A,C . PASS . GT 0/0 1/2 2/2 1 1002 . G A,GA . PASS . GT 0/0 1/2 1/1 1 1003 . CC TT . PASS . GT 0/0 0/1 1/1 1 1003 . CC TT,CT . PASS . GT 0/0 0/1 1/1 1 1003 . CACC TAT . PASS . GT 0/0 0/1 1/1 1 1004 . C . PASS . GT 0/0 0/1 1/1 1 1005 . C . . PASS . GT 0/0 0/0 0/0 1 1006 . CC CC . PASS . GT 0/0 0/1 1/1 1 1006 . C G,T . PASS . GT 0/0 1/1 2/2 X 1000 . C A . PASS . GT 0/0 0 1 X 1001 . C A . PASS . GT ./. 0 . bcftools-1.21/test/stats.vaf.1.chk000066400000000000000000000022421467060157400170000ustar00rootroot00000000000000SN 0 number of samples: 2 SN 0 number of records: 10 SN 0 number of no-ALTs: 0 SN 0 number of SNPs: 9 SN 0 number of MNPs: 0 SN 0 number of indels: 1 SN 0 number of others: 0 SN 0 number of multiallelic sites: 3 SN 0 number of multiallelic SNP sites: 2 TSTV 0 1 10 0.10 0 9 0.00 SiS 0 1 4 1 3 2 0 0 2 AF 0 0.000000 4 1 3 3 0 0 3 AF 0 0.490000 7 0 7 0 0 0 0 QUAL 0 . 9 0 9 1 IDD 0 -5 1 0 . IDD 0 -4 1 1 0.43 IDD 0 -3 1 1 0.29 ST 0 A>C 0 ST 0 A>G 0 ST 0 A>T 0 ST 0 C>A 8 ST 0 C>G 1 ST 0 C>T 1 ST 0 G>A 0 ST 0 G>C 0 ST 0 G>T 1 ST 0 T>A 0 ST 0 T>C 0 ST 0 T>G 0 DP 0 1 8 40.000000 0 0.000000 DP 0 2 3 15.000000 0 0.000000 DP 0 3 2 10.000000 0 0.000000 DP 0 5 2 10.000000 0 0.000000 DP 0 6 2 10.000000 0 0.000000 DP 0 7 1 5.000000 0 0.000000 DP 0 8 1 5.000000 0 0.000000 DP 0 10 1 5.000000 0 0.000000 PSC 0 a 0 0 9 0 10 1 3.7 2 0 0 0 PSC 0 b 2 0 8 1 7 0 3.0 0 0 0 0 PSI 0 a 0 0 0 0.00 0 1 0 0 PSI 0 b 0 0 0 0.00 0 0 0 0 HWE 0 0.000000 3 0.000000 0.000000 0.990000 HWE 0 0.490000 7 0.990000 0.990000 0.990000 VAF 0 a 0,0,0,1,2,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,4 0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0 VAF 0 b 0,0,0,1,1,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,4 0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 bcftools-1.21/test/stats.vaf.vcf000066400000000000000000000014061467060157400166530ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=ref.fa ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT a b chr1 603697 . C A,T . . . GT:AD 0/1:0,1,0 0/2:0,0,1 chr1 847172 . C A . . . GT:AD 0/1:1,1 0/1:1,1 chr1 895916 . C A,G . . . GT:AD 1/2:8,2,0 0/0:8,0,0 chr1 940526 . CTTTTT C,CTT,CT . . . GT:AD 2/3:2,0,2,3 0/0:2,0,0,0 chr1 1054587 . C A . . . GT:AD 0/1:5,1 0/1:5,1 chr1 1123455 . C A . . . GT:AD 0/1:0,1 0/1:0,1 chr1 1130454 . C A . . . GT:AD 0/1:4,1 0/1:4,1 chr1 1145661 . G T . . . GT:AD 0/1:0,1 0/1:0,1 chr1 1198538 . C A . . . GT:AD 0/1:0,1 0/1:0,1 chr1 1349818 . C A . . . GT:AD 0/1:2,1 0/1:2,1 bcftools-1.21/test/tabix.1.3000151.out000066400000000000000000000001031467060157400170420ustar00rootroot000000000000001 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 bcftools-1.21/test/tabix.2.3199812.out000066400000000000000000000001121467060157400170720ustar00rootroot000000000000002 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 bcftools-1.21/test/tag2tag.LPL.1.1.vcf000066400000000000000000000030171467060157400172170ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 chr 1 . A C,G . . . GT:LAD:LPL:LAA:AD:PL 0/0:31:0:.:31,.,.:0,.,.,.,.,. 0/1:17,16:86,0,57:1:17,16,.:86,0,57,.,.,. chr 2 . G A,T . . . GT:LAD:LPL:LAA:AD:PL 0/2:13,12:82,0,55:2:13,.,12:82,.,.,0,.,55 0/0:34:0:.:34,.,.:0,.,.,.,.,. chr 3 . T G . . . GT:LAD:LPL:LAA:AD:PL 0/0:29:0:.:29,.:0,.,. 0/1:13,8:81,0,53:1:13,8:81,0,53 chr 4 . A C . . . GT:LAD:LPL:LAA:AD:PL 1/1:0,27:88,61,0:1:0,27:88,61,0 0/1:18,19:85,0,52:1:18,19:85,0,52 chr 5 . T TA,TAA,TAAA,TAAAA,TAAAAA,TAAAAAA,TAAAAAAA . . . GT:LAD:LPL:LAA:AD:PL 5/2:0,8,13:305,339,82,220,0,61:5,2:0,.,13,.,.,8,.,.:305,.,.,220,.,61,.,.,0,.,.,.,.,.,.,339,.,.,.,.,82,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. 2/2:0,25:90,56,0:2:0,.,25,.,.,.,.,.:90,.,.,56,.,0,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. bcftools-1.21/test/tag2tag.LPL.1.2.vcf000066400000000000000000000016271467060157400172250ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 chr 1 . A C,G . . . GT:AD:PL 0/0:31,.,.:0,.,.,.,.,. 0/1:17,16,.:86,0,57,.,.,. chr 2 . G A,T . . . GT:AD:PL 0/2:13,.,12:82,.,.,0,.,55 0/0:34,.,.:0,.,.,.,.,. chr 3 . T G . . . GT:AD:PL 0/0:29,.:0,.,. 0/1:13,8:81,0,53 chr 4 . A C . . . GT:AD:PL 1/1:0,27:88,61,0 0/1:18,19:85,0,52 chr 5 . T TA,TAA,TAAA,TAAAA,TAAAAA,TAAAAAA,TAAAAAAA . . . GT:AD:PL 5/2:0,.,13,.,.,8,.,.:305,.,.,220,.,61,.,.,0,.,.,.,.,.,.,339,.,.,.,.,82,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. 2/2:0,.,25,.,.,.,.,.:90,.,.,56,.,0,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,.,. bcftools-1.21/test/tag2tag.LPL.1.3.vcf000066400000000000000000000023361467060157400172240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 chr 1 . A C,G . . . GT:AD:PL 0/0:31,0,0:0,255,255,255,255,255 0/1:17,16,0:86,0,57,255,255,255 chr 2 . G A,T . . . GT:AD:PL 0/2:13,0,12:82,255,255,0,255,55 0/0:34,0,0:0,255,255,255,255,255 chr 3 . T G . . . GT:AD:PL 0/0:29,0:0,255,255 0/1:13,8:81,0,53 chr 4 . A C . . . GT:AD:PL 1/1:0,27:88,61,0 0/1:18,19:85,0,52 chr 5 . T TA,TAA,TAAA,TAAAA,TAAAAA,TAAAAAA,TAAAAAAA . . . GT:LAD:LPL:LAA 5/2:0,8,13:305,339,82,220,0,61:5,2 2/2:0,25:90,56,0:2 bcftools-1.21/test/tag2tag.LPL.1.vcf000066400000000000000000000017411467060157400170620ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT smpl1 smpl2 chr 1 . A C,G . . . GT:LAD:LPL:LAA 0/0:31:0:. 0/1:17,16:86,0,57:1 chr 2 . G A,T . . . GT:LAD:LPL:LAA 0/2:13,12:82,0,55:2 0/0:34:0:. chr 3 . T G . . . GT:LAD:LPL:LAA 0/0:29:0:. 0/1:13,8:81,0,53:1 chr 4 . A C . . . GT:LAD:LPL:LAA 1/1:0,27:88,61,0:1 0/1:18,19:85,0,52:1 chr 5 . T TA,TAA,TAAA,TAAAA,TAAAAA,TAAAAAA,TAAAAAAA . . . GT:LAD:LPL:LAA 5/2:0,8,13:305,339,82,220,0,61:5,2 2/2:0,25:90,56,0:2 bcftools-1.21/test/test-rbuf.c000066400000000000000000000042351467060157400163240ustar00rootroot00000000000000/* test/test-rbuf.c -- rbuf_t test harness. Copyright (C) 2014 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include "rbuf.h" void debug_print(rbuf_t *rbuf, int *dat) { int i; for (i=-1; rbuf_next(rbuf, &i); ) printf(" %2d", i); printf("\n"); for (i=-1; rbuf_next(rbuf, &i); ) printf(" %2d", dat[i]); printf("\n"); } int main(int argc, char **argv) { int i, j, *dat = (int*)calloc(10,sizeof(int)); rbuf_t rbuf; rbuf_init(&rbuf,10); rbuf.f = 5; // force wrapping for (i=0; i<9; i++) { j = rbuf_append(&rbuf); dat[j] = i+1; } printf("Inserted 1-9 starting at offset 5:\n"); debug_print(&rbuf, dat); i = rbuf_kth(&rbuf, 3); printf("4th is %d\n", dat[i]); printf("Deleting 1-2:\n"); rbuf_shift_n(&rbuf, 2); debug_print(&rbuf, dat); printf("Prepending 0-8:\n"); for (i=0; i<9; i++) { j = rbuf_prepend(&rbuf); dat[j] = i; } debug_print(&rbuf, dat); printf("Expanding:\n"); rbuf_expand0(&rbuf,int,rbuf.n+1,dat); debug_print(&rbuf, dat); free(dat); return 0; } bcftools-1.21/test/test-regidx.c000066400000000000000000000364111467060157400166510ustar00rootroot00000000000000/* test/test-regidx.c -- Regions index test harness. gcc -g -Wall -O0 -I. -I../htslib/ -L../htslib regidx.c -o test-regidx test-regidx.c -lhts Copyright (C) 2014, 2016, 2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include "regidx.h" static int verbose = 0; void HTS_FORMAT(HTS_PRINTF_FMT, 1, 2) debug(const char *format, ...) { if ( verbose<2 ) return; va_list ap; va_start(ap, format); vfprintf(stderr, format, ap); va_end(ap); } void HTS_FORMAT(HTS_PRINTF_FMT, 1, 2) info(const char *format, ...) { if ( verbose<1 ) return; va_list ap; va_start(ap, format); vfprintf(stderr, format, ap); va_end(ap); } void HTS_FORMAT(HTS_PRINTF_FMT, 1, 2) HTS_NORETURN error(const char *format, ...) { va_list ap; va_start(ap, format); vfprintf(stderr, format, ap); va_end(ap); exit(-1); } int custom_parse(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { // Use the standard parser for CHROM,FROM,TO int i, ret = regidx_parse_tab(line,chr_beg,chr_end,beg,end,NULL,NULL); if ( ret!=0 ) return ret; // Skip the fields that were parsed above char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; for (i=0; i<3; i++) { while ( *ss && !isspace(*ss) ) ss++; if ( !*ss ) return -2; // wrong number of fields while ( *ss && isspace(*ss) ) ss++; } if ( !*ss ) return -2; // Parse the payload char *se = ss; while ( *se && !isspace(*se) ) se++; char **dat = (char**) payload; *dat = (char*) malloc(se-ss+1); memcpy(*dat,ss,se-ss+1); (*dat)[se-ss] = 0; return 0; } void custom_free(void *payload) { char **dat = (char**)payload; free(*dat); } void test_sequential_access(void) { // Init index with no file name, we will insert the regions manually regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL); if ( !idx ) error("init failed\n"); // Insert regions kstring_t str = {0,0,0}; int i, n = 10; for (i=0; ibeg!=itr->end || itr->beg+1!=10*(i+1) ) error("listing failed, expected %d, found %d\n",10*(i+1),itr->beg+1); str.l = 0; ksprintf(&str,"%d",itr->beg+1); if ( strcmp(regitr_payload(itr,char*),str.s) ) error("listing failed, expected payload \"%s\", found \"%s\"\n",str.s,regitr_payload(itr,char*)); i++; } if ( i!=n ) error("Expected %d regions, listed %d\n", n,i); debug("ok: listed %d regions\n", n); // Clean up regitr_destroy(itr); regidx_destroy(idx); free(str.s); } void test_custom_payload(void) { // Init index with no file name, we will insert the regions manually regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL); if ( !idx ) error("init failed\n"); // Insert regions char *line; line = "1 10000000 10000000 1:10000000-10000000"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); line = "1 20000000 20000001 1:20000000-20000001"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); line = "1 20000002 20000002 1:20000002-20000002"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); line = "1 30000000 30000000 1:30000000-30000000"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); // Test regitr_t *itr = regitr_init(idx); int from, to; from = to = 10000000; if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); if ( strcmp("1:10000000-10000000",regitr_payload(itr,char*)) ) error("query failed: 1:%d-%d vs %s\n", from,to,regitr_payload(itr,char*)); if ( !regidx_overlap(idx,"1",from-2,to-1,itr) ) error("query failed: 1:%d-%d\n",from-1,to); if ( !regidx_overlap(idx,"1",from-2,to+3,itr) ) error("query failed: 1:%d-%d\n",from-1,to+2); if ( regidx_overlap(idx,"1",from-2,to-2,itr) ) error("query failed: 1:%d-%d\n",from-1,to-1); from = to = 20000000; if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); from = to = 20000002; if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); from = to = 30000000; if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); // Clean up regitr_destroy(itr); regidx_destroy(idx); } void get_random_region(uint32_t min, uint32_t max, uint32_t *beg, uint32_t *end) { uint64_t b = random(), e = random(); *beg = min + (b * (max-min)) / INT32_MAX; *end = *beg + (e * (max-*beg)) / INT32_MAX; } void test_random(int nregs, uint32_t min, uint32_t max) { min--; max--; // Init index with no file name, we will insert the regions manually regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL); if ( !idx ) error("init failed\n"); // Test region uint32_t beg,end; get_random_region(min,max,&beg,&end); // Insert regions int i, nexp = 0; kstring_t str = {0,0,0}; for (i=0; i=beg && b<=end ) nexp++; } // Test regitr_t *itr = regitr_init(idx); int nhit = 0, ret = regidx_overlap(idx,"1",beg,end,itr); if ( nexp && !ret ) error("query failed, expected %d overlap(s), found none: %d-%d\n", nexp,beg+1,end+1); if ( !nexp && ret ) error("query failed, expected no overlaps, found some: %d-%d\n", beg+1,end+1); while ( ret && regitr_overlap(itr) ) { str.l = 0; ksprintf(&str,"1:%"PRIu32"-%"PRIu32"",itr->beg+1,itr->end+1); if ( strcmp(str.s,regitr_payload(itr,char*)) ) error("query failed, incorrect payload: %s vs %s (%d-%d)\n",str.s,regitr_payload(itr,char*),beg+1,end+1); if ( itr->beg > end || itr->end < beg ) error("query failed, incorrect hit: %d-%d vs %d-%d, payload %s\n", beg+1,end+1,itr->beg+1,itr->end+1,regitr_payload(itr,char*)); nhit++; } if ( nexp!=nhit ) error("query failed, expected %d overlap(s), found %d: %d-%d\n",nexp,nhit,beg+1,end+1); debug("ok: found %d overlaps\n", nexp); // Clean up regitr_destroy(itr); regidx_destroy(idx); free(str.s); } void test_explicit(char *tgt, char *qry, char *exp) { regidx_t *idx = regidx_init(NULL,regidx_parse_reg,NULL,0,NULL); char *beg = tgt, *end, *exp_ori = exp; kstring_t str = {0,0,0}; while ( *beg ) { end = tgt; while ( *end && *end!=';' ) end++; str.l = 0; kputsn(beg, end-beg, &str); debug("insert: %s\n", str.s); if ( regidx_insert(idx,str.s)!=0 ) error("insert failed: %s\n", str.s); beg = *end ? end + 1 : end; } beg = qry; while ( *beg ) { end = qry; while ( *end && *end!=';' ) end++; str.l = 0; kputsn(beg, end-beg, &str); beg = *end ? end + 1 : end; char *chr_beg, *chr_end; uint32_t reg_beg, reg_end; if ( regidx_parse_reg(str.s, &chr_beg, &chr_end, ®_beg, ®_end, NULL, NULL)!=0 ) error("could not parse: %s in %s\n", str.s, qry); chr_end[1] = 0; int hit = regidx_overlap(idx,chr_beg,reg_beg,reg_end,NULL); if ( *exp=='1' ) { if ( !hit ) error("query failed, there should be a hit .. %s:%d-%d\n",chr_beg,reg_beg+1,reg_end+1); debug("ok: overlap found for %s:%d-%d\n",chr_beg,reg_beg+1,reg_end+1); } else if ( *exp=='0' ) { if ( hit ) error("query failed, there should be no hit .. %s:%d-%d\n",chr_beg,reg_beg+1,reg_end+1); debug("ok: no overlap found for %s:%d-%d\n",chr_beg,reg_beg+1,reg_end+1); } else error("could not parse: %s\n", exp_ori); exp++; } free(str.s); regidx_destroy(idx); } void create_line_bed(char *line, char *chr, int start, int end) { sprintf(line,"%s\t%d\t%d\n",chr,start-1,end); } void create_line_tab(char *line, char *chr, int start, int end) { sprintf(line,"%s\t%d\t%d\n",chr,start,end); } void create_line_reg(char *line, char *chr, int start, int end) { sprintf(line,"%s:%d-%d\n",chr,start,end); } typedef void (*set_line_f)(char *line, char *chr, int start, int end); void test(set_line_f set_line, regidx_parse_f parse) { regidx_t *idx = regidx_init(NULL,parse,NULL,0,NULL); if ( !idx ) error("init failed\n"); char line[250], *chr = "1"; int i, n = 10, start, end, nhit; for (i=1; ibeg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); debug("\t %d-%d\n",itr->beg+1,itr->end+1); nhit++; } if ( nhit!=1 ) error("query failed, expected one hit, found %d: %s:%d-%d\n",nhit,chr,start,end); // one hit start = end = 10*i+1; if ( !regidx_overlap(idx,chr,start-1,end-1,itr) ) error("query failed, there should be a hit: %s:%d-%d\n",chr,start,end); debug("ok: overlap(s) found for %s:%d-%d\n",chr,start,end); nhit = 0; while ( regitr_overlap(itr) ) { if ( itr->beg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); debug("\t %d-%d\n",itr->beg+1,itr->end+1); nhit++; } if ( nhit!=1 ) error("query failed, expected one hit, found %d: %s:%d-%d\n",nhit,chr,start,end); // two hits start = 10*i; end = start+1; if ( !regidx_overlap(idx,chr,start-1,end-1,itr) ) error("query failed, there should be a hit: %s:%d-%d\n",chr,start,end); debug("ok: overlap(s) found for %s:%d-%d\n",chr,start,end); nhit = 0; while ( regitr_overlap(itr) ) { if ( itr->beg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); debug("\t %d-%d\n",itr->beg+1,itr->end+1); nhit++; } if ( nhit!=2 ) error("query failed, expected two hits, found %d: %s:%d-%d\n",nhit,chr,start,end); // fully contained interval, one hit start = 20000*i - 5000; end = 20000*i + 3000; set_line(line,chr,start,end); if ( !regidx_overlap(idx,chr,start-1,end-1,itr) ) error("query failed, there should be a hit: %s:%d-%d\n",chr,start,end); debug("ok: overlap(s) found for %s:%d-%d\n",chr,start,end); nhit = 0; while ( regitr_overlap(itr) ) { if ( itr->beg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); debug("\t %d-%d\n",itr->beg+1,itr->end+1); nhit++; } if ( nhit!=1 ) error("query failed, expected one hit, found %d: %s:%d-%d\n",nhit,chr,start,end); } regitr_destroy(itr); regidx_destroy(idx); } static void usage(void) { fprintf(stderr, "Usage: test-regidx [OPTIONS]\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -h, --help this help message\n"); fprintf(stderr, " -s, --seed random seed\n"); fprintf(stderr, " -v, --verbose increase verbosity by giving multiple times\n"); exit(1); } int main(int argc, char **argv) { static struct option loptions[] = { {"help",0,0,'h'}, {"verbose",0,0,'v'}, {"seed",1,0,'s'}, {0,0,0,0} }; int c; int seed = (int)time(NULL); while ((c = getopt_long(argc, argv, "hvs:",loptions,NULL)) >= 0) { switch (c) { case 's': seed = atoi(optarg); break; case 'v': verbose++; break; default: usage(); break; } } info("Testing sequential access\n"); test_sequential_access(); info("Testing TAB\n"); test(create_line_tab,regidx_parse_tab); info("Testing REG\n"); test(create_line_reg,regidx_parse_reg); info("Testing BED\n"); test(create_line_bed,regidx_parse_bed); info("Testing custom payload\n"); test_custom_payload(); info("Testing cases encountered in past\n"); test_explicit("12:2064519-2064763","12:2064488-2067434","1"); int i, ntest = 1000, nreg = 50; srandom(seed); info("%d randomized tests, %d regions per test. Random seed is %d\n", ntest,nreg,seed); for (i=0; i # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. use strict; use warnings; use Carp; #use IPC::Open2; use FindBin; use lib "$FindBin::Bin"; use Getopt::Long; use File::Temp qw/ tempfile tempdir /; use Cwd qw/ abs_path /; my $opts = parse_params(); run_test(\&test_usage,$opts,cmd=>'bcftools'); run_test(\&test_tabix,$opts,in=>'merge.a',reg=>'2:3199812-3199812',out=>'tabix.2.3199812.out'); run_test(\&test_tabix,$opts,in=>'merge.a',reg=>'1:3000151-3000151',out=>'tabix.1.3000151.out'); run_test(\&test_index,$opts,in=>'large_chrom_csi_limit',reg=>'chr20:1-2147483647',out=>'large_chrom_csi_limit.20.1.2147483647.out'); # 2147483647 (1<<31-1) is the current chrom limit for csi. bcf conversion and indexing fail above this run_test(\&test_index,$opts,in=>'large_chrom_csi_limit',reg=>'chr20',out=>'large_chrom.20.1.2147483647.out'); # this fails until bug resolved run_test(\&test_vcf_idxstats,$opts,in=>'idx',args=>'-s',out=>'idx.out'); run_test(\&test_vcf_idxstats,$opts,in=>'idx',args=>'-n',out=>'idx_count.out'); run_test(\&test_vcf_idxstats,$opts,in=>'empty',args=>'-s',out=>'empty.idx.out'); run_test(\&test_vcf_idxstats,$opts,in=>'empty',args=>'-n',out=>'empty.idx_count.out'); run_test(\&test_vcf_check,$opts,in=>'check',out=>'check.chk'); run_test(\&test_vcf_check_merge,$opts,in=>'check',out=>'check_merge.chk'); run_test(\&test_vcf_stats,$opts,in=>['stats.a','stats.b'],out=>'stats.chk',args=>'-s -'); run_test(\&test_vcf_stats,$opts,in=>['stats.a','stats.b'],out=>'stats.B.chk',args=>'-s B'); run_test(\&test_vcf_stats,$opts,in=>['stats.counts'],out=>'stats.counts.chk',args=>'-s -'); run_test(\&test_vcf_stats,$opts,in=>['stats.counts'],out=>'stats.counts.2.chk',args=>q[-s - -i 'type="snp"']); run_test(\&test_vcf_stats,$opts,in=>['stats.vaf'],out=>'stats.vaf.1.chk',args=>q[-s -]); run_test(\&test_vcf_isec,$opts,in=>['isec.a','isec.b'],out=>'isec.ab.out',args=>'-n =2'); run_test(\&test_vcf_isec,$opts,in=>['isec.a','isec.b'],out=>'isec.ab.flt.out',args=>'-n =2 -i"STRLEN(REF)==2"'); run_test(\&test_vcf_isec,$opts,in=>['isec.a','isec.b'],out=>'isec.ab.both.out',args=>'-n =2 -c both'); run_test(\&test_vcf_isec,$opts,in=>['isec.a','isec.b'],out=>'isec.ab.any.out',args=>'-n =2 -c any'); run_test(\&test_vcf_isec,$opts,in=>['isec.a','isec.b'],out=>'isec.ab.C.out',args=>'-C -c any'); run_test(\&test_vcf_isec2,$opts,vcf_in=>['isec.a'],tab_in=>'isec',out=>'isec.tab.out',args=>''); run_test(\&test_vcf_isec,$opts,in=>['isec-miss.1.1','isec-miss.1.2','isec-miss.1.3'],out=>'isec-miss.1.1.out',args=>'-n +1 -r 20:100,20:140,12:55,20:140,20:100'); run_test(\&test_vcf_isec,$opts,in=>['isec-miss.1.1','isec-miss.1.2','isec-miss.1.3'],out=>'isec-miss.1.1.out',args=>'-R {PATH}/isec-miss.1.regs.txt -n +1'); run_test(\&test_vcf_isec,$opts,in=>['isec-miss.2.1','isec-miss.2.2','isec-miss.2.3'],out=>'isec-miss.2.1.out',args=>'-n +1 -r 20:100,20:140,12:55,20:140,20:100'); run_test(\&test_vcf_isec,$opts,in=>['isec-miss.2.1','isec-miss.2.2','isec-miss.2.3'],out=>'isec-miss.2.1.out',args=>'-R {PATH}/isec-miss.1.regs.txt -n +1'); run_test(\&test_vcf_merge,$opts,in=>['merge.11.a','merge.11.b'],out=>'merge.11.1.out',args=>''); run_test(\&test_vcf_merge,$opts,in=>['merge.join.a','merge.join.b'],out=>'merge.join.1.out',args=>'-i AF:join'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a'],out=>'merge.LPL.0.out',args=>'--force-single'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a','merge.LPL.b','merge.LPL.c'],out=>'merge.LPL.1.out',args=>'--force-samples'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a','merge.LPL.b','merge.LPL.c'],out=>'merge.LPL.2.out',args=>'--force-samples -L 1'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a','merge.LPL.b','merge.LPL.c'],out=>'merge.LPL.3.out',args=>'--force-samples -L 2'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a','merge.LPL.b','merge.LPL.c'],out=>'merge.LPL.4.out',args=>'--force-samples -L 3'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a','merge.LPL.b','merge.LPL.c'],out=>'merge.LPL.5.out',args=>'--force-samples -L 4'); run_test(\&test_vcf_merge,$opts,in=>['merge.LPL.a','merge.LPL.b','merge.LPL.c'],out=>'merge.LPL.6.out',args=>'--force-samples -L 5'); run_test(\&test_vcf_merge,$opts,in=>['merge.a','merge.b','merge.c'],out=>'merge.abc.out',args=>'--force-samples'); run_test(\&test_vcf_merge,$opts,in=>['merge.a','merge.b','merge.c'],out=>'merge.abc.2.out',args=>'--force-samples -Fx'); run_test(\&test_vcf_merge,$opts,in=>['merge.a','merge.b','merge.c'],out=>'merge.abc.3.out',args=>'--force-samples -0'); run_test(\&test_vcf_merge,$opts,in=>['merge.2.a','merge.2.b'],out=>'merge.2.none.out',args=>'--force-samples -m none'); run_test(\&test_vcf_merge,$opts,in=>['merge.2.a','merge.2.b'],out=>'merge.2.both.out',args=>'--force-samples -m both'); run_test(\&test_vcf_merge,$opts,in=>['merge.2.a','merge.2.b'],out=>'merge.2.all.out',args=>'--force-samples -m all'); run_test(\&test_vcf_merge,$opts,in=>['merge.3.a','merge.3.b'],out=>'merge.3.out',args=>'--force-samples -i TR:sum,TA:sum,TG:sum'); run_test(\&test_vcf_merge,$opts,in=>['merge.4.a','merge.4.b'],out=>'merge.4.out',args=>'--force-samples -m id'); run_test(\&test_vcf_merge,$opts,in=>['gvcf.merge.1','gvcf.merge.2','gvcf.merge.3'],out=>'gvcf.merge.1.out',args=>'--gvcf -'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.2.a','merge.gvcf.2.b','merge.gvcf.2.c'],out=>'merge.gvcf.2.out',args=>'--gvcf -',types=>['vcf']); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.2.a','merge.gvcf.2.b','merge.gvcf.2.c'],out=>'merge.gvcf.2.1.out',args=>'--gvcf - -m both,*',types=>['vcf']); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.2.a','merge.gvcf.2.b','merge.gvcf.2.c'],out=>'merge.gvcf.2.2.out',args=>'--gvcf - -m both,**',types=>['vcf']); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.3.a','merge.gvcf.3.b'],out=>'merge.gvcf.3.out',args=>'--gvcf - -i SRC:join',types=>['vcf']); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.4.a','merge.gvcf.4.b'],out=>'merge.gvcf.4.out',args=>'--gvcf -'); run_test(\&test_vcf_merge,$opts,in=>['merge.5.a','merge.5.b'],out=>'merge.5.out'); run_test(\&test_vcf_merge,$opts,in=>['merge.6.a','merge.6.b'],out=>'merge.6.out'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.7.a','merge.gvcf.7.b'],out=>'merge.gvcf.7.out',args=>'--gvcf -'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.8.a','merge.gvcf.8.b'],out=>'merge.gvcf.8.out',args=>'--gvcf -'); run_test(\&test_vcf_merge,$opts,in=>['merge.7.a','merge.7.b'],out=>'merge.9.out',args=>'--force-samples'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.9a','merge.gvcf.9b','merge.gvcf.9c','merge.gvcf.9d'],out=>'merge.gvcf.9.1.out',args=>'--gvcf {PATH}/gvcf.fa'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.9a','merge.gvcf.9b','merge.gvcf.9c','merge.gvcf.9d'],out=>'merge.gvcf.9.2.out',args=>'--gvcf {PATH}/gvcf.fa -r 22:21-23'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.9a','merge.gvcf.9b','merge.gvcf.9c','merge.gvcf.9d','merge.gvcf.9e'],out=>'merge.gvcf.9.3.out',args=>'--gvcf {PATH}/gvcf.fa'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.9a','merge.gvcf.9b','merge.gvcf.9c','merge.gvcf.9d','merge.gvcf.9e'],out=>'merge.gvcf.9.4.out',args=>'--gvcf {PATH}/gvcf.fa -r 22:21-23'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.10.a','merge.gvcf.10.b'],out=>'merge.gvcf.10.1.out',args=>''); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.10.a','merge.gvcf.10.b'],out=>'merge.gvcf.10.2.out',args=>'-m none'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.10.a','merge.gvcf.10.b'],out=>'merge.gvcf.10.3.out',args=>'-g {PATH}/merge.gvcf.10.fa'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.10.a','merge.gvcf.10.b'],out=>'merge.gvcf.10.4.out',args=>'-g {PATH}/merge.gvcf.10.fa -m none'); run_test(\&test_vcf_merge,$opts,in=>['merge.noidx.a','merge.noidx.b','merge.noidx.c'],out=>'merge.noidx.abc.out',args=>''); run_test(\&test_vcf_merge,$opts,in=>['merge.noidx.a','merge.noidx.b','merge.noidx.c'],out=>'merge.noidx.abc.out',args=>'--no-index',noidx=>1); run_test(\&test_vcf_merge,$opts,in=>['merge.8.a','merge.8.b'],out=>'merge.8.out',args=>''); run_test(\&test_vcf_merge,$opts,in=>['merge.8.a','merge.8.b'],out=>'merge.8.out',args=>'-i AN:sum,AC:sum'); run_test(\&test_vcf_merge,$opts,in=>['merge.9.a','merge.9.b'],out=>'merge.9.1.out',args=>''); run_test(\&test_vcf_merge,$opts,in=>['merge.9.a','merge.9.b'],out=>'merge.9.2.out',args=>'-i AN:sum,AC:sum'); run_test(\&test_vcf_merge,$opts,in=>['merge.10.a','merge.10.b'],out=>'merge.10.1.out',args=>'-m none'); run_test(\&test_vcf_merge,$opts,in=>['merge.10.a','merge.10.b'],out=>'merge.10.2.out',args=>'-m both'); run_test(\&test_vcf_merge,$opts,in=>['merge.10.a','merge.10.b'],out=>'merge.10.3.out',args=>'-m snp-ins-del'); run_test(\&test_vcf_merge,$opts,in=>['merge.mrules.1.a','merge.mrules.1.b'],out=>'merge.mrules.1.1.out',args=>'--gvcf -'); run_test(\&test_vcf_merge,$opts,in=>['merge.mrules.1.a','merge.mrules.1.b'],out=>'merge.mrules.1.2.out',args=>'--gvcf - -M AD:.,PL:.'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.5.a','merge.gvcf.5.b'],out=>'merge.gvcf.5.1.out',args=>'--gvcf -'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.5.a','merge.gvcf.5.b'],out=>'merge.gvcf.5.1.out',args=>'--gvcf - --merge none'); run_test(\&test_vcf_merge,$opts,in=>['merge.gvcf.11.a','merge.gvcf.11.b','merge.gvcf.11.c'],out=>'merge.gvcf.11.1.out',args=>'--gvcf -'); # run_test(\&test_vcf_merge_big,$opts,in=>'merge_big.1',out=>'merge_big.1.1',nsmpl=>79000,nfiles=>79,nalts=>486,args=>''); # commented out for speed run_test(\&test_vcf_query,$opts,in=>'query.string',out=>'query.string.1.out',args=>q[-f '%CHROM\\t%POS\\t%CLNREVSTAT\\n' -i'CLNREVSTAT="criteria_provided,_conflicting_interpretations"']); run_test(\&test_vcf_query,$opts,in=>'query.string',out=>'query.string.1.out',args=>q[-f '%CHROM\\t%POS\\t%CLNREVSTAT\\n' -i'CLNREVSTAT="criteria_provided" || CLNREVSTAT="_conflicting_interpretations"']); run_test(\&test_vcf_query,$opts,in=>'query.string',out=>'query.string.2.out',args=>q[-f '%CHROM\\t%POS\\t%CLNREVSTAT\\n' -i'CLNREVSTAT="criteria_provided" && CLNREVSTAT="_conflicting_interpretations"']); run_test(\&test_vcf_query,$opts,in=>'query.string.2',out=>'query.string.2.1.out',args=>q[-f '%CHROM\\t%POS\\t%INFO/STR\\n' -i'INFO/STR=@{PATH}/query.string.2.1.txt']); run_test(\&test_vcf_query,$opts,in=>'query.string.2',out=>'query.string.2.2.out',args=>q[-f '%CHROM\\t%POS[\\t%STR]\\n' -i'FMT/STR=@{PATH}/query.string.2.2.txt']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.out',args=>q[-f '%CHROM\\t%POS\\t%REF\\t%ALT\\t%DP4\\t%AN[\\t%GT\\t%TGT]\\n']); run_test(\&test_vcf_query,$opts,in=>'query.variantkey',out=>'query.variantkey.hex.out',args=>q[-f '%RSX\\t%VKX\\n']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.2.out',args=>q[-f'%XRI\\n' -i'XRI[*]>1111']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.3.out',args=>q[-f'%XRF\\n' -i'XRF[*]=2e6']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[5]="PQR"']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[*]="GHI"']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[2]~"H"']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[3]!~"H" && XGS!="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[*]~"H"']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.5.out',args=>q[-f'%POS %REF %ALT\\n' -i'REF~"C" && ALT[*]~"CT"']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.6.out',args=>q[-f'%POS %REF %ALT\\n' -i'N_ALT=2']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.7.out',args=>q[-f'%POS %AN\\n' -i'AN!=2*N_SAMPLES']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.8.out',args=>q[-f'%POS[ %GL]\\n' -i'min(abs(GL[*:0]))=10']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.9.out',args=>q[-f'%POS %CIGAR\\n' -i'strlen(CIGAR[*])=4']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.10.out',args=>q[-f'%POS[ %GT]\\n' -i'AC[0]=3']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.10.out',args=>q[-f'%POS[ %GT]\\n' -i'AF[0]=3/4']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.11.out',args=>q[-f'%POS[ %GT]\\n' -i'MAC[0]=1']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.11.out',args=>q[-f'%POS[ %GT]\\n' -i'MAF[0]=1/4']); run_test(\&test_vcf_query,$opts,in=>'view.vectors',out=>'query.12.out',args=>q[-f'I8=%I8 I16=%I16 I32=%I32 IF=%IF IA8=%IA8 IA16=%IA16 IA32=%IA32 IAF=%IAF IA8=%IA8{1} IA16=%IA16{1} IA32=%IA32{1} IAF=%IAF{1} [ %F8:%F16:%F32:%FF]\\n']); run_test(\&test_vcf_query,$opts,in=>'query.filter',out=>'query.13.out',args=>q[-f'[%POS %SAMPLE %GT\\n]' -i'GT ="1"']); run_test(\&test_vcf_query,$opts,in=>'query.filter',out=>'query.14.out',args=>q[-f'[%POS %SAMPLE %GT\\n]' -i'GT!="1"']); run_test(\&test_vcf_query,$opts,in=>'query.filter',out=>'query.15.out',args=>q[-f'[%POS %SAMPLE %GT\\n]' -e'GT ="1"']); run_test(\&test_vcf_query,$opts,in=>'query.filter',out=>'query.16.out',args=>q[-f'[%POS %SAMPLE %GT\\n]' -e'GT!="1"']); run_test(\&test_vcf_query,$opts,in=>'query.2',out=>'query.17.out',args=>q[-f'%XX_A %XX.A %XX.A0 %xx.a0\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.18.out',args=>q[-i'IINT="."' -f'%POS %IINT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.19.out',args=>q[-i'IINT!="."' -f'%POS %IINT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.18.out',args=>q[-e'IINT!="."' -f'%POS %IINT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.19.out',args=>q[-e'IINT="."' -f'%POS %IINT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.20.out',args=>q[-i'IFLT="."' -f'%POS %IFLT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.21.out',args=>q[-i'IFLT!="."' -f'%POS %IFLT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.20.out',args=>q[-e'IFLT!="."' -f'%POS %IFLT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.21.out',args=>q[-e'IFLT="."' -f'%POS %IFLT\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.22.out',args=>q[-i'ISTR="."' -f'%POS %ISTR\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.23.out',args=>q[-i'ISTR!="."' -f'%POS %ISTR\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.23.out',args=>q[-e'ISTR="."' -f'%POS %ISTR\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.22.out',args=>q[-e'ISTR!="."' -f'%POS %ISTR\\n']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.24.out',args=>q[-i'FILTER="q11"' -f'%POS %ISTR\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.11',out=>'query.76.out',args=>q[-i'FILTER="A"' -f'%POS %FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.11',out=>'query.77.out',args=>q[-i'FILTER!="A"' -f'%POS %FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.11',out=>'query.78.out',args=>q[-i'FILTER~"A"' -f'%POS %FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.11',out=>'query.79.out',args=>q[-i'FILTER!~"A"' -f'%POS %FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.25.out',args=>q[-f'%LINE']); run_test(\&test_vcf_query,$opts,in=>'query.filter-type',out=>'query.26.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type="snp"']); run_test(\&test_vcf_query,$opts,in=>'query.filter-type',out=>'query.27.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type~"snp"']); run_test(\&test_vcf_query,$opts,in=>'query.filter-type',out=>'query.28.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type!="snp"']); run_test(\&test_vcf_query,$opts,in=>'query.filter-type',out=>'query.29.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type!~"snp"']); run_test(\&test_vcf_query,$opts,in=>'query.filter-type',out=>'query.67.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'INFO/TYPE="xxx"']); run_test(\&test_vcf_query,$opts,in=>'filter-missing-floats',out=>'query.30.out',args=>q[-f'%POS\\t%A_AF\\t%B_AF\\t%C_AF\\n' -i'A_AF>=0.0001 || B_AF >= 0.0001 || C_AF >= 0.0001']); run_test(\&test_vcf_query,$opts,in=>'filter-missing-floats',out=>'query.31.out',args=>q[-f'%POS\\t%A_AF\\t%B_AF\\t%C_AF\\n' -e'A_AF>=0.0001 || B_AF >= 0.0001 || C_AF >= 0.0001']); run_test(\&test_vcf_query,$opts,in=>'missing',out=>'query.32.out',args=>q[-i'FMT/FINT!="."' -f'[\t%FINT]\\n']); run_test(\&test_vcf_query,$opts,in=>'query.filter.2',out=>'query.33.out',args=>q[-f'[%GT]\\n' -i'GT~"0/[1-9]" || GT~"[1-9]/0"']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.34.out',args=>q[-f'[%POS %SAMPLE %FGS\\n]\\n' -i'FGS[*:1-2,4]="EE"']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.34.out',args=>q[-f'[%POS %SAMPLE %FGS\\n]\\n' -i'"EE"=FGS[*:1-2,4]']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.35.out',args=>q[-f'[%POS %SAMPLE %FGI\\n]\\n' -i'FGI[*:1-2,5]=6']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.35.out',args=>q[-f'[%POS %SAMPLE %FGI\\n]\\n' -i'6=FGI[*:1-2,5]']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.36.out',args=>q[-f'[%POS %SAMPLE %FGF\\n]\\n' -i'FGF[*:1-3,4]=5e-5']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.37.out',args=>q[-f'[%POS %SAMPLE %FGS\\n]\\n' -i'FGS[*:4]!="EE"']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.38.out',args=>q[-f'[%POS %SAMPLE %FGS\\n]\\n' -i'FGS[*:4]="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.39.out',args=>q[-f'[%POS %SAMPLE %FGS\\n]\\n' -i'FGS[*:4]!="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.40.out',args=>q[-f'[%POS %SAMPLE %FGI\\n]\\n' -i'FGI[*:1-2,5]="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.41.out',args=>q[-f'[%POS %SAMPLE %FGI\\n]\\n' -i'FGI[*:1-2,5]!="."']); run_test(\&test_vcf_query,$opts,in=>'filter.5',out=>'query.42.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP=1 | FMT/DP=2']); run_test(\&test_vcf_query,$opts,in=>'filter.5',out=>'query.43.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP=1 | FMT/DP="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.44.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP=19']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.45.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP=19 | FMT/DP="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.46.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP=19 || FMT/DP="."']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.47.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP[0]=19']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.48.out',args=>q[-f'[%POS %SAMPLE %DP\\n]\\n' -i'FMT/DP[0]!=19']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.49.out',args=>q[-f'[%POS %SAMPLE %DP %GQ\\n]\\n' -i'FMT/DP=19 & FMT/GQ=589']); run_test(\&test_vcf_query,$opts,in=>'view.filter',out=>'query.50.out',args=>q[-f'[%POS %SAMPLE %DP %GQ\\n]\\n' -i'FMT/DP=19 && FMT/GQ=1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.3',out=>'query.51.out',args=>q[-f'[\\t%GT\\n]\\n' -i'GT~"1" && GT~"2"']); run_test(\&test_vcf_query,$opts,in=>'query.filter.3',out=>'query.52.out',args=>q[-f'[\\t%GT\\n]\\n' -i'GT~"1" & GT~"2"']); run_test(\&test_vcf_query,$opts,in=>'query.filter.3',out=>'query.53.out',args=>q[-f'%POS[\\t%GT]\\n' -i'COUNT(GT="het")=1']); run_test(\&test_vcf_query,$opts,in=>'filter.5',out=>'query.54.out',args=>q[-f'[%POS %SAMPLE %AD\\n]\\n' -i'AD[:0]+AD[:1] > 12']); run_test(\&test_vcf_query,$opts,in=>'query.filter.4',out=>'query.55.out',args=>q[-f'%POS\\t%REF\\t%ALT[\\t%GT]\\n' -e'TYPE!="snp" || ALT="*"']); run_test(\&test_vcf_query,$opts,in=>'view',out=>'query.56.out',args=>q[-f'%ID\\n' -i 'ID=@].$$opts{path}.q[/query.56.out']); run_test(\&test_vcf_query,$opts,in=>'query.filter.5',out=>'query.57.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GT\\t%AD\\n]' -i'GT="het" & binom(FMT/AD)>0.01']); run_test(\&test_vcf_query,$opts,in=>'query.filter.5',out=>'query.58.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GT\\t%AD\\n]' -i'GT="het" & binom(FMT/AD[:0],FMT/AD[:1])>0.01']); run_test(\&test_vcf_query,$opts,in=>'query.filter.5',out=>'query.59.out',args=>q[-f'%POS\\t%AD\\n' -i'binom(INFO/AD[0],INFO/AD[1])>0.01']); run_test(\&test_vcf_query,$opts,in=>'query.filter.5',out=>'query.92.out',args=>q[-f'[%POS\\t%GT\\t%SAMPLE\\t%AD\\n]' -i'FMT/AD[GT]==10']); run_test(\&test_vcf_query,$opts,in=>'query.filter.5',out=>'query.93.out',args=>q[-f'[%POS\\t%GT\\t%SAMPLE\\t%AD\\n]' -i'sSUM(FMT/AD[GT])==210']); run_test(\&test_vcf_query,$opts,in=>'query.filter.5',out=>'query.94.out',args=>q[-f'[%POS\\t%GT\\t%SAMPLE\\t%AD\\n]' -i'FMT/AD[0:GT]==30']); run_test(\&test_vcf_query,$opts,in=>'query.gtidx.1',out=>'query.gtidx.1.out',args=>q[-f'[%GT %TC %TS %TI %TF\\n]' -i'FMT/TF[:GT]==1 && FMT/TF[:GT]==2']); run_test(\&test_vcf_query,$opts,in=>'query.gtidx.1',out=>'query.gtidx.1.out',args=>q[-f'[%GT %TC %TS %TI %TF\\n]' -i'FMT/TI[:GT]==1 && FMT/TF[:GT]==2']); run_test(\&test_vcf_query,$opts,in=>'query.gtidx.1',out=>'query.gtidx.1.out',args=>q[-f'[%GT %TC %TS %TI %TF\\n]' -i'FMT/TS[:GT]=="BB" && FMT/TS[:GT]=="CC"']); run_test(\&test_vcf_query,$opts,in=>'query.gtidx.1',out=>'query.gtidx.1.out',args=>q[-f'[%GT %TC %TS %TI %TF\\n]' -i'FMT/TC[:GT]=="B" && FMT/TC[:GT]=="C"']); run_test(\&test_vcf_query,$opts,in=>'query.gtidx.1',out=>'query.gtidx.2.out',args=>q[-f'[%GT %TI\\n]' -i'FMT/TI[:GT]=="."']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.60.out',args=>q[-f'%CHROM %POS\\n' -i'CHROM="4"']); run_test(\&test_vcf_query,$opts,in=>'query.negative',out=>'query.61.out',args=>q[-f'%POS\\t%TAG1\\n' -i'(TAG1>=-129 && TAG1<=-120) || (TAG1>=-32769 && TAG1<=-32760)']); run_test(\&test_vcf_query,$opts,in=>'query.negative',out=>'query.61.out',args=>q[-f'%POS\\t%TAGV1\\n' -i'(TAGV1>=-129 && TAGV1<=-120) || (TAGV1>=-32769 && TAGV1<=-32760)']); run_test(\&test_vcf_query,$opts,in=>'query.negative',out=>'query.62.out',args=>q[-f'%POS\\t%TAG2\\n' -i'(TAG2>=-129 && TAG2<=-120) || (TAG2>=-32769 && TAG2<=-32760)']); run_test(\&test_vcf_query,$opts,in=>'query.negative',out=>'query.62.out',args=>q[-f'%POS\\t%TAGV2\\n' -i'(TAGV2>=-129 && TAGV2<=-120) || (TAGV2>=-32769 && TAGV2<=-32760)']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.63.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GQ\\n]' -i'N_PASS(GQ<20)==1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.11',out=>'query.80.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GT\\n]' -i'N_PASS(GT="alt")==1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.11',out=>'query.81.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GT\\n]' -i'N_PASS(GT="alt")!=1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.11',out=>'query.81.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GT\\n]' -e'N_PASS(GT="alt")==1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.11',out=>'query.80.out',args=>q[-f'[%POS\\t%SAMPLE\\t%GT\\n]' -e'N_PASS(GT="alt")!=1']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.64.out',args=>q[-f'%CHROM\\t%POS\\t%INFO\\t%FORMAT\\n' -s D,C]); run_test(\&test_vcf_query,$opts,in=>'query.pbinom.1',out=>'query.65.out',args=>q[-f'[%POS %SAMPLE %GT %AD %PBINOM(AD)\\n]' -i'phred(binom(FMT/AD))>=0']); run_test(\&test_vcf_query,$opts,in=>'query.filter.6',out=>'query.66.out',args=>q[-f'%POS\\n' -i'POS==16777217 || POS==33554432 || POS=118673904']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'sum(II)==6']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'sum(FORMAT/FI)==7']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'avg(II)==2']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'avg(FORMAT/FI)==1.75']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'mean(II)==2']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'mean(FORMAT/FI)==1.75']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'median(II)==2']); run_test(\&test_vcf_query,$opts,in=>'query.filter.7',out=>'query.68.out',args=>q[-f'%POS\\t%II[\\t%FI]\\n' -i'median(FORMAT/FI)==1.5']); run_test(\&test_vcf_query,$opts,in=>'query.filter.8',out=>'query.69.out',args=>q[-f'%POS\\t%REF\\t%ALT\\t%ILEN\\n' -i'%ILEN==1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.8',out=>'query.70.out',args=>q[-f'%POS\\t%REF\\t%ALT\\t%ILEN\\n' -i'ILEN==1']); run_test(\&test_vcf_query,$opts,in=>'query.filter.9',out=>'query.71.out',args=>q[-f'[%POS %SAMPLE %AD\\n]' -i'FMT/AD[:0] < FMT/AD[:1]']); run_test(\&test_vcf_query,$opts,in=>'query.filter.9',out=>'query.72.out',args=>q[-f'[%POS %SAMPLE %AD\\n]' -i'FMT/AD[:0] > FMT/AD[:1]']); run_test(\&test_vcf_query,$opts,in=>'query.filter.13',out=>'query.84.out',args=>q[-f'[ %AD\\n]' -i'AD[:1] / sum(AD[*]) > 0.5']); run_test(\&test_vcf_query,$opts,in=>'query.filter.10',out=>'query.73.out',args=>q[-f'%POS %NUM_TAG\\n' -i'COUNT(INFO/NUM_TAG)=2']); run_test(\&test_vcf_query,$opts,in=>'query.filter.10',out=>'query.74.out',args=>q[-f'%POS %STR_TAG\\n' -i'COUNT(INFO/STR_TAG)=2']); run_test(\&test_vcf_query,$opts,in=>'query',out=>'query.75.out',args=>q[-f '%CHROM:%POS\\t%N_PASS(GT="alt" & GQ>110)\\t[\\t%GT]\\t[\\t%GQ]\n']); run_test(\&test_vcf_query,$opts,in=>'query.filter.12',out=>'query.82.out',args=>q[-f '%CHROM:%POS[\\t%SAMPLE=%GT]\\n' -e 'GT="mis"' -s 1,3,0]); run_test(\&test_vcf_query,$opts,in=>'query.filter.12',out=>'query.83.out',args=>q[-f '%CHROM:%POS[\\t%SAMPLE=%GT]\\n' -e 'GT="mis"' -s 0,1,3]); run_test(\&test_vcf_query,$opts,in=>'query.smpl',out=>'query.smpl.1.out',args=>q[-f "[%SAMPLE %GT\n]" -S {PATH}/query.smpl.11.txt]); run_test(\&test_vcf_query,$opts,in=>'query.smpl',out=>'query.smpl.2.out',args=>q[-l -S {PATH}/query.smpl.11.txt]); run_test(\&test_vcf_query,$opts,in=>'query.smpl',out=>'query.smpl.3.out',args=>q[-f "[%SAMPLE %GT\n]" -S ^{PATH}/query.smpl.11.txt]); run_test(\&test_vcf_query,$opts,in=>'query.smpl',out=>'query.smpl.4.out',args=>q[-l -S ^{PATH}/query.smpl.11.txt]); run_test(\&test_vcf_query,$opts,in=>'query.smpl',out=>'query.smpl.5.out',args=>q[-f "[%SAMPLE %GT\n]" -S {PATH}/query.smpl.txt]); run_test(\&test_vcf_query,$opts,in=>'query.smpl',out=>'query.smpl.6.out',args=>q[-l -S {PATH}/query.smpl.txt]); run_test(\&test_vcf_query,$opts,in=>'query.filter.id',out=>'query.filter.id.1.out',args=>q[-f'%ID\\n' -i'ID~"s12"']); run_test(\&test_vcf_query,$opts,in=>'query.filter.id',out=>'query.filter.id.2.out',args=>q[-f'%ID\\n' -i'ID="rs123"']); run_test(\&test_vcf_query,$opts,in=>'query.filter.id',out=>'query.filter.id.3.out',args=>q[-f'%ID\\n' -i'ID="abc"']); run_test(\&test_vcf_query,$opts,in=>'query.filter.id',out=>'query.filter.id.3.out',args=>q[-f'%ID\\n' -i'ID=@].$$opts{path}.q[/query.filter.id.3.txt']); run_test(\&test_vcf_query,$opts,in=>'query.filter.id',out=>'query.filter.id.4.out',args=>q[-f'%ID\\n' -i'ID!="abc"']); run_test(\&test_vcf_query,$opts,in=>'query.filter.id',out=>'query.filter.id.4.out',args=>q[-f'%ID\\n' -i'ID!=@].$$opts{path}.q[/query.filter.id.3.txt']); run_test(\&test_vcf_query,$opts,in=>'filter.12',out=>'query.85.out',args=>q[-i'FILTER="A"' -f'%FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.12',out=>'query.86.out',args=>q[-i'FILTER~"A"' -f'%FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.12',out=>'query.87.out',args=>q[-i'FILTER="A;B"' -f'%FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.12',out=>'query.88.out',args=>q[-i'FILTER!="A;B"' -f'%FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.12',out=>'query.89.out',args=>q[-i'FILTER~"A;B"' -f'%FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.12',out=>'query.90.out',args=>q[-i'FILTER!~"A;B"' -f'%FILTER\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.10',out=>'query.91.out',args=>q[-i'DP%10==2' -f'[ %DP]\\n']); run_test(\&test_vcf_query,$opts,in=>'filter.13',out=>'query.99.out',args=>q[-i'REF="N"' -f'%CHROM %POS %REF %ALT %QUAL\\n']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.95.out',args=>q[-H -f'[%CHROM %POS %SAMPLE %DP %GT\\n]']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.96.out',args=>q[-H -f'[%CHROM %POS %SAMPLE %DP %GT\\t]\\n']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.97.out',args=>q[-H -f'%CHROM %POS[ %SAMPLE %DP %GT]\\n']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.97.out',args=>q[-H -f'%CHROM %POS[ %SAMPLE %DP %GT]']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.98.out',args=>q[-H -f'%CHROM %POS[ %SAMPLE][ %DP][ %GT]\\n']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.98.out',args=>q[-H -f'%CHROM %POS[ %SAMPLE][ %DP][ %GT]']); run_test(\&test_vcf_query,$opts,in=>'query.header',out=>'query.98.2.out',args=>q[-HH -f'%CHROM %POS[ %SAMPLE][ %DP][ %GT]']); run_test(\&test_vcf_query,$opts,in=>'query.filter-or',out=>'query.filter-or.1.out',args=>q[-f'[%SAMPLE %DP\\n]' -i'DP=1 || DP=2']); run_test(\&test_vcf_query,$opts,in=>'query.filter-or',out=>'query.filter-or.2.out',args=>q[-f'[%SAMPLE %DP\\n]' -i'DP=1 | DP=2']); run_test(\&test_vcf_norm,$opts,in=>'norm.sort',out=>'norm.sort.1.out',args=>'-m -'); run_test(\&test_vcf_norm,$opts,in=>'norm.sort',out=>'norm.sort.2.out',args=>'-m - -S lex'); run_test(\&test_vcf_norm,$opts,in=>'norm.join-missing-ploidy',out=>'norm.join-missing-ploidy.1.out',args=>'-m +both'); run_test(\&test_vcf_norm,$opts,in=>'norm.split.5',out=>'norm.split.5.1.out',args=>'-m - --multi-overlaps .'); run_test(\&test_vcf_norm,$opts,in=>'norm.symbolic.3',out=>'norm.symbolic.3.1.out',fai=>'norm.symbolic.3',args=>''); run_test(\&test_vcf_norm,$opts,in=>'norm',out=>'norm.out',fai=>'norm',args=>'-cx'); run_test(\&test_vcf_norm,$opts,in=>'norm.split',out=>'norm.split.out',args=>'-m-'); run_test(\&test_vcf_norm,$opts,in=>'norm.split.2',out=>'norm.split.2.out',args=>'-m-'); run_test(\&test_vcf_norm,$opts,in=>'norm.split.3',out=>'norm.split.3.out',args=>'-m- --force'); run_test(\&test_vcf_norm,$opts,in=>'norm.split.4',out=>'norm.split.4.1.out',args=>'-m-'); run_test(\&test_vcf_norm,$opts,in=>'norm.split.4',out=>'norm.split.4.2.out',args=>'-m- --keep-sum AD'); run_test(\&test_vcf_norm,$opts,in=>'norm.split',fai=>'norm',out=>'norm.split.and.norm.out',args=>'-m-'); run_test(\&test_vcf_norm,$opts,in=>'norm.merge',out=>'norm.merge.out',args=>'-m+'); run_test(\&test_vcf_norm,$opts,in=>'norm.merge.2',out=>'norm.merge.2.out',args=>'-m+'); run_test(\&test_vcf_norm,$opts,in=>'norm.merge.3',out=>'norm.merge.3.out',args=>'-m+'); run_test(\&test_vcf_norm,$opts,in=>'norm.merge',out=>'norm.merge.strict.out',args=>'-m+ -s'); run_test(\&test_vcf_norm,$opts,in=>'norm.setref',out=>'norm.setref.out',args=>'-Nc s',fai=>'norm'); run_test(\&test_vcf_norm,$opts,in=>'norm.telomere',out=>'norm.telomere.out',fai=>'norm'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup',out=>'norm.rmdup.1.out',args=>'-d snps'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup',out=>'norm.rmdup.2.out',args=>'-d indels'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup',out=>'norm.rmdup.3.out',args=>'-d both'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup',out=>'norm.rmdup.4.out',args=>'-d all'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup',out=>'norm.rmdup.5.out',args=>'-d none'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup',out=>'norm.rmdup.5.out',args=>'-d exact'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.2',out=>'norm.rmdup.2.1.out',args=>'-d none'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.2',out=>'norm.rmdup.2.1.out',args=>'-d exact'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.2',out=>'norm.rmdup.2.1.out',args=>'-d indels'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.2',out=>'norm.rmdup.2.2.out',args=>'-d any'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.2',out=>'norm.rmdup.2.2.out',args=>'-d both'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.2',out=>'norm.rmdup.2.2.out',args=>'-d snps'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.3',fai=>'norm.rmdup.3',out=>'norm.rmdup.3.1.out',args=>'-d exact'); run_test(\&test_vcf_norm,$opts,in=>'norm.rmdup.3',fai=>'norm.rmdup.3',out=>'norm.rmdup.3.2.out',args=>'-d all'); run_test(\&test_vcf_norm,$opts,in=>'norm.2',fai=>'norm.2',out=>'norm.2.out',args=>'-c s -a'); run_test(\&test_vcf_norm,$opts,in=>'norm.iupac',fai=>'norm.iupac',out=>'norm.iupac.out',args=>'-c s'); run_test(\&test_vcf_norm,$opts,in=>'norm.3',fai=>'norm.3',out=>'norm.3.out',args=>'-c s'); run_test(\&test_vcf_norm,$opts,in=>'norm.3',fai=>'norm.3',out=>'norm.3.2.out',args=>q[-c s -i'alt="N"']); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.1',out=>'atomize.split.1.0.out',args=>['-a --old-rec-tag OLD_REC','-m -any --force']); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.1',out=>'atomize.split.1.1.out',args=>['-m -any --old-rec-tag OLD_REC --force','-a']); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.1',out=>'atomize.split.1.1.out',args=>'-m -any --old-rec-tag OLD_REC --force -a'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.1',out=>'atomize.split.1.2.out',args=>'--atomize --atom-overlaps . --old-rec-tag OLD_REC'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.1',out=>'atomize.split.1.3.out',args=>'--atomize --old-rec-tag OLD_REC'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.2',out=>'atomize.split.2.1.out',args=>'--atomize --old-rec-tag OLD_REC'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.2',out=>'atomize.split.2.2.out',args=>'--atomize --atom-overlaps . --old-rec-tag OLD_REC'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.3',out=>'atomize.split.3.1.out',args=>'--atomize --atom-overlaps .'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.4',out=>'atomize.split.4.1.out',args=>'--atomize --atom-overlaps . --old-rec-tag OLD_REC'); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.4',out=>'atomize.split.4.2.out',args=>q[--atomize --atom-overlaps . --old-rec-tag OLD_REC -i 'ILEN=0']); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.5',out=>'atomize.split.5.1.out',args=>q[--atomize --old-rec-tag OLD_REC --atom-overlaps .]); run_test(\&test_vcf_norm,$opts,in=>'atomize.split.5',out=>'atomize.split.5.2.out',args=>q[--atomize --old-rec-tag OLD_REC]); run_test(\&test_vcf_norm,$opts,in=>'norm.4',out=>'norm.4.1.out',args=>'-m +both'); run_test(\&test_vcf_norm,$opts,in=>'norm.4',out=>'norm.4.2.out',args=>'-m +any'); run_test(\&test_vcf_norm,$opts,in=>'norm.5',out=>'norm.5.1.out',args=>'-m - --multi-overlaps 0'); run_test(\&test_vcf_norm,$opts,in=>'norm.5',out=>'norm.5.2.out',args=>'-m - --multi-overlaps .'); run_test(\&test_vcf_norm,$opts,in=>'norm.m-any',out=>'norm.m-any.1.out',args=>'-m -any'); run_test(\&test_vcf_norm,$opts,in=>'norm.phased-split',out=>'norm.phased-split.1.out',args=>'-m -any'); run_test(\&test_vcf_norm,$opts,in=>'norm.phased-join',out=>'norm.phased-join.1.out',args=>'-m +any'); run_test(\&test_vcf_norm,$opts,in=>'norm.symbolic',fai=>'norm.symbolic',out=>'norm.symbolic.1.out',args=>'--old-rec-tag ORI'); run_test(\&test_vcf_norm,$opts,in=>'norm.symbolic.2',fai=>'norm.symbolic',out=>'norm.symbolic.2.out',args=>'--old-rec-tag ORI'); run_test(\&test_vcf_norm,$opts,in=>'norm.right-align',fai=>'norm.right-align',out=>'norm.right-align.1.out',args=>'--old-rec-tag ORI'); run_test(\&test_vcf_norm,$opts,in=>'norm.right-align',fai=>'norm.right-align',out=>'norm.right-align.2.out',args=>'--old-rec-tag ORI -g {PATH}/norm.right-align.gff'); run_test(\&test_vcf_norm,$opts,in=>'norm.atom-split-norm',fai=>'norm.atom-split-norm',out=>'norm.atom-split-norm.1.out',args=>'--old-rec-tag ORI -a -m -any'); run_test(\&test_vcf_norm,$opts,in=>'norm.string-tags',out=>'norm.string-tags.1.out',args=>'-m -any'); run_test(\&test_vcf_norm,$opts,in=>'norm.split.merge',out=>'norm.split.merge.1.out',args=>['-m -','-m +both']); run_test(\&test_vcf_norm,$opts,in=>'norm.split.merge',out=>'norm.split.merge.2.out',args=>['-m -','-m +indels']); run_test(\&test_vcf_norm,$opts,in=>'norm.split.merge',out=>'norm.split.merge.3.out',args=>['-m -','-m +snps']); run_test(\&test_vcf_norm,$opts,in=>'norm.split.merge',out=>'norm.split.merge.3.out',args=>['-m -','-m +snps']); run_test(\&test_vcf_norm,$opts,in=>'norm.split.merge',out=>'norm.split.merge.4.out',args=>['-m -','-m +any']); run_test(\&test_vcf_norm,$opts,in=>'norm.split.merge',out=>'norm.split.merge.5.out',args=>q[-m - -i 'type="snp"']); run_test(\&test_vcf_norm,$opts,in=>'norm.merge.4',out=>'norm.merge.4.1.out',args=>'-m +any'); run_test(\&test_vcf_norm,$opts,in=>'norm.merge.4',out=>'norm.merge.4.2.out',args=>'-m +both'); run_test(\&test_vcf_view,$opts,in=>'filter.string.1',out=>'filter.string.1.1.out',args=>q[-i 'INFO/TAG=@{PATH}/filter.string.1.txt']); run_test(\&test_vcf_view,$opts,in=>'filter.string.1',out=>'filter.string.1.1.out',args=>q[-i 'FMT/TAG=@{PATH}/filter.string.1.txt']); run_test(\&test_vcf_view,$opts,in=>'merge.gvcf.2.a',out=>'merge.gvcf.2.a.1.out',args=>'-HA'); run_test(\&test_vcf_view,$opts,in=>'merge.gvcf.2.a',out=>'merge.gvcf.2.a.2.out',args=>'-HAA'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.1.out',args=>'',reg=>'-r 1'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.1.out',args=>'',reg=>'-r 1:1-2'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.1.out',args=>'',reg=>'-r 1:1,1:2'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.2.out',args=>'',reg=>'-r 1:1-1'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.3.out',args=>'',reg=>'-r {1:1}'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.3.out',args=>'',reg=>'-r {1:1}:1-2'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.3.out',args=>'',reg=>'-r {1:1}:1,{1:1}:2'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.4.out',args=>'',reg=>'-r {1:1}:1-1'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.5.out',args=>'',reg=>'-r {1:1-1}'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.5.out',args=>'',reg=>'-r {1:1-1}:1-2'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.5.out',args=>'',reg=>'-r {1:1-1}:1,{1:1-1}:2'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',out=>'weird-chr-names.6.out',args=>'',reg=>'-r {1:1-1}:1-1'); run_test(\&test_vcf_view,$opts,in=>'weird-chr-names',args=>'',reg=>'-r {1:1-1}-2',expected_failure=>1); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.1.out',args=>'-aUc1 -C1 -s NA00002 -v snps',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.2.out',args=>'-f PASS -Xks NA00003',reg=>'-r20,Y'); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.3.out',args=>'-xs NA00003',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.4.out',args=>q[-i 'QUAL==999 && (FS<20 || FS>=41.02) && ICF>-0.1 && HWE*2>1.2'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.5.out',args=>q[-p],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.6.out',args=>q[-P],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.7.out',args=>q[-hm2 -M2 -q0.3 -Q0.7],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.8.out',args=>q[-Hu],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.9.out',args=>q[-GVsnps],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.10.out',args=>q[-ne 'INDEL=1 || PV4[0]<0.006'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view',out=>'view.exclude.out',args=>'-s ^NA00003',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.omitgenotypes',out=>'view.omitgenotypes.out',args=>'',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.omitgenotypes',out=>'view.dropgenotypes.out',args=>'-G',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.omitgenotypes',out=>'view.dropgenotypes.noheader.out',args=>'-HG',reg=>''); run_test(\&test_vcf_view,$opts,in=>'many.alleles',out=>'many.alleles.trim.out',args=>'-a',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.vectors',out=>'view.vectors.A.out',args=>'-asA',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.vectors',out=>'view.vectors.B.out',args=>'-asB',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.vectors.2',out=>'view.vectors.C.out',args=>'-asA',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter',out=>'view.filter.1.out',args=>q[-H -i'FMT/FGS[*:0]="AAAAAA"'],reg=>''); # test expressions run_test(\&test_vcf_view,$opts,in=>'view.filter',out=>'view.filter.2.out',args=>q[-H -i'FMT/FGS[*:2]="C"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter',out=>'view.filter.3.out',args=>q[-H -i'FMT/FGS[*:4]="EE"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter',out=>'view.filter.4.out',args=>q[-H -i'FMT/FRS[*:1]="BB"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter',out=>'view.filter.5.out',args=>q[-H -i'TXT0="text"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.chrs',out=>'view.chrs.out',args=>'',reg=>'',tgts=>'view.chrs.tab'); run_test(\&test_vcf_view,$opts,in=>'filter.2',out=>'filter.11.out',args=>q[-i 'POS>=3062917'],reg=>'1:3062917-3157410'); run_test(\&test_vcf_view,$opts,in=>'idx.1',out=>'idx.1.out',args=>q[-H -r 1:10,1:12,1:10]); run_test(\&test_vcf_view,$opts,in=>'idx.2',out=>'idx.2.out',args=>q[-H -r 1:1172777-1172804,1:1172806-1172808]); run_test(\&test_vcf_view,$opts,in=>'idx.2',out=>'idx.2.out',args=>q[-H -R {PATH}/idx.2.bed]); run_test(\&test_vcf_view,$opts,in=>'idx.3',out=>'idx.3.out',args=>q[-H -R {PATH}/idx.3.bed]); run_test(\&test_vcf_view,$opts,in=>'idx.4',out=>'idx.4.out',args=>q[-H -R {PATH}/idx.4.bed]); run_test(\&test_vcf_view,$opts,in=>'view-t',out=>'view-t.1.out',args=>'-Ht 2',reg=>''); run_test(\&test_vcf_view,$opts,in=>'view-t',out=>'view-t.2.out',args=>'-Ht 3',reg=>''); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.0.out',args=>q[-H -r chr1:100-200 --regions-overlap 0]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.1.out',args=>q[-H -r chr1:100-200 --regions-overlap 1]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.2.out',args=>q[-H -r chr1:100-200 --regions-overlap 2]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.0.out',args=>q[-H -t chr1:100-200 --targets-overlap 0]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.1.out',args=>q[-H -t chr1:100-200 --targets-overlap 1]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.2.out',args=>q[-H -t chr1:100-200 --targets-overlap 2]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.neg0.out',args=>q[-H -t ^chr1:100-200 --targets-overlap 0]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.neg1.out',args=>q[-H -t ^chr1:100-200 --targets-overlap 1]); run_test(\&test_vcf_view,$opts,in=>'overlap',out=>'overlap.neg2.out',args=>q[-H -t ^chr1:100-200 --targets-overlap 2]); run_test(\&test_vcf_64bit,$opts,in=>'view64bit.1',out=>'view64bit.1.out',do_bcf=>1); run_test(\&test_vcf_64bit,$opts,in=>'view64bit.2',out=>'view64bit.2.out',do_bcf=>1); run_test(\&test_vcf_64bit,$opts,in=>'view64bit.3',out=>'view64bit.3.out'); # large coordinates don't work with BCF run_test(\&test_vcf_64bit,$opts,in=>'view64bit.4',out=>'view64bit.4.out',do_bcf=>1); run_test(\&test_vcf_64bit,$opts,in=>'view64bit.5',out=>'view64bit.5.out',do_bcf=>1); run_test(\&test_vcf_view,$opts,in=>'view.minmaxac',out=>'view.minmaxac.1.out',args=>q[-H -C5:nonmajor],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.minmaxac',out=>'view.minmaxac.2.out',args=>q[-H -c6:nonmajor],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.minmaxac',out=>'view.minmaxac.1.out',args=>q[-H -q0.3:major],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter.annovar',out=>'view.filter.annovar.1.out',args=>q[-H -i 'Gene.refGene=="RAD21L1"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter.annovar',out=>'view.filter.annovar.2.out',args=>q[-H -i 'Gene.refGene~"NOD"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view.filter.annovar',out=>'view.filter.annovar.3.out',args=>q[-H -i 'LJB2_MutationTaster=="0.291000"'],reg=>''); run_test(\&test_vcf_view,$opts,in=>'view-a',out=>'view-a.1.out',args=>q[-H -a]); run_test(\&test_vcf_view,$opts,in=>'view.sites',out=>'view.sites.1.out',args=>'',tgts=>'view.sites.txt'); run_test(\&test_vcf_view,$opts,in=>'view.sites',out=>'view.sites.1.out',args=>'',tgts=>'view.sites.txt.gz'); run_test(\&test_vcf_head,$opts,in=>'mpileup.2.vcf',in_nheaders=>22); run_test(\&test_vcf_head2,$opts,in=>'mpileup.2',out=>'head.1.out',args=>'-s0'); run_test(\&test_vcf_head2,$opts,in=>'mpileup.2',out=>'head.2.out',args=>'-s1'); run_test(\&test_vcf_head2,$opts,in=>'mpileup.2',out=>'head.3.out',args=>'-s2 -h2'); run_test(\&test_vcf_call,$opts,in=>'mpileup',out=>'mpileup.1.out',args=>'-mv'); run_test(\&test_vcf_call,$opts,in=>'mpileup',out=>'mpileup.2.out',args=>'-mg0'); run_test(\&test_vcf_call,$opts,in=>'mpileup',out=>'mpileup.3.out',args=>'-mv -S {PATH}/mpileup.3.samples'); run_test(\&test_vcf_call,$opts,in=>'mpileup',out=>'mpileup.4.out',args=>'-mv -S {PATH}/mpileup.4.samples'); run_test(\&test_vcf_call,$opts,in=>'mpileup',out=>'mpileup.5.out',args=>'-mv -S {PATH}/mpileup.5.samples'); run_test(\&test_vcf_call,$opts,in=>'mpileup.X',out=>'mpileup.X.out',args=>'-mv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.samples'); run_test(\&test_vcf_call,$opts,in=>'mpileup.X',out=>'mpileup.X.out',args=>'-mv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.ped'); run_test(\&test_vcf_call,$opts,in=>'mpileup.X',out=>'mpileup.X.2.out',args=>'-mv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.2.samples'); run_test(\&test_vcf_call,$opts,in=>'mpileup.NA19213.NA19129',out=>'mpileup.hwe.1.out',args=>'-mv'); run_test(\&test_vcf_call,$opts,in=>'mpileup.NA19213.NA19129',out=>'mpileup.hwe.1b.out',args=>'-mv -G - --group-samples-tag AD'); run_test(\&test_vcf_call,$opts,in=>'mpileup.hwe',out=>'mpileup.hwe.2.out',args=>'-mv'); run_test(\&test_vcf_call,$opts,in=>'mpileup.hwe',out=>'mpileup.hwe.3.out',args=>'-mv -G - --group-samples-tag AD'); # 21,3,0 becomes 0/0 because of the prior -P run_test(\&test_vcf_call,$opts,in=>'mpileup.hwe',out=>'mpileup.hwe.4.out',args=>'-mv -G {PATH}/mpileup.hwe.samples --group-samples-tag AD'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup',out=>'mpileup.cAls.out',tab=>'mpileup'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.2',out=>'mpileup.cAls.2.out',tab=>'mpileup.2'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.3',out=>'mpileup.cAls.3.out',tab=>'mpileup.3',args=>'-i'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.3',out=>'mpileup.cAls.4.out',tab=>'mpileup.4',args=>'-i'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.3',out=>'mpileup.cAls.5.out',tab=>'mpileup.5',args=>'-i'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.4',out=>'mpileup.cAls.6.out',tab=>'mpileup.6',args=>'-i'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.5',out=>'mpileup.cAls.7.out',tab=>'mpileup.7',args=>'-i'); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.cals.1',out=>'mpileup.cals.8.out',tab=>'mpileup.cals.1',args=>''); run_test(\&test_vcf_call_cAls,$opts,in=>'mpileup.cals.2',out=>'mpileup.cals.9.out',tab=>'mpileup.cals.2',args=>''); run_test(\&test_vcf_call,$opts,in=>'mpileup.c',out=>'mpileup.c.1.out',args=>'-cv'); # run_test(\&test_vcf_call,$opts,in=>'mpileup.c',out=>'mpileup.c.2.out',args=>'-cg0'); run_test(\&test_vcf_call,$opts,in=>'mpileup.c.X',out=>'mpileup.c.X.out',args=>'-cv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.samples'); run_test(\&test_vcf_call,$opts,in=>'mpileup.c.X',out=>'mpileup.c.X.out',args=>'-cv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.ped'); run_test(\&test_vcf_call,$opts,in=>'mpileup.c.X',out=>'mpileup.c.X.2.out',args=>'-cv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.2.samples'); run_test(\&test_vcf_call,$opts,in=>'call-G',out=>'call-G.1.out',args=>'-mv'); run_test(\&test_vcf_call,$opts,in=>'call-G',out=>'call-G.2.out',args=>'-mv -G - --group-samples-tag AD'); run_test(\&test_vcf_call,$opts,in=>'call-G.2',out=>'call-G.2.1.out',args=>'-mv -F AN_POP,AC_POP'); run_test(\&test_vcf_call,$opts,in=>'call.af-fixation',out=>'call.af-fixation.1.out',args=>'-m'); run_test(\&test_vcf_call,$opts,in=>'call.af-fixation',out=>'call.af-fixation.2.out',args=>'-m -G {PATH}/call.af-fixation.txt'); run_test(\&test_vcf_call,$opts,in=>'call.af-fixation',out=>'call.af-fixation.3.out',args=>'-m -G {PATH}/call.af-fixation.txt -a GP,GQ'); run_test(\&test_vcf_filter,$opts,in=>'view.filter',out=>'view.filter.6.out',args=>q[-S. -e'TXT0="text"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'view.filter',out=>'view.filter.7.out',args=>q[-S. -e'FMT/FRS[*:1]="BB"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'view.filter',out=>'view.filter.8.out',args=>q[-S. -e'FMT/FGS[*:0]="AAAAAA"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'view.filter',out=>'view.filter.9.out',args=>q[-S. -e'FMT/FGS[*:1]="BBB"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'view.filter',out=>'view.filter.10.out',args=>q[-S. -e'FMT/FGS[*:4]="EE"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'view.filter',out=>'view.filter.11.out',args=>q[-S. -e'FMT/STR="XX"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'view.filter.2',out=>'view.filter.12.out',args=>q[-S. -e'FMT/FILTER="aaa"'],reg=>''); run_test(\&test_vcf_filter,$opts,in=>'filter.1',out=>'filter.1.out',args=>'-mx -g2 -G2'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.2.out',args=>q[-e'QUAL==59.2 || (INDEL=0 & (FMT/GQ=25 | FMT/DP=10))' -sModified -S.]); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.3.out',args=>q[-e'INFO/DP=19'],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.4.out',args=>q[-e'INFO/DP=19' -s XX],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.5.out',args=>q[-e'INFO/DP=19' -s XX -m+],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.6.out',args=>q[-e'INFO/DP=19' -s XX -mx],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.7.out',args=>q[-e'INFO/DP=19' -s XX -m+x],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.3.out',args=>q[-e'FMT/GT="0/2"'],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.4.out',args=>q[-e'FMT/GT="0/2"' -s XX],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.5.out',args=>q[-e'FMT/GT="0/2"' -s XX -m+],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.6.out',args=>q[-e'FMT/GT="0/2"' -s XX -mx],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.3',out=>'filter.7.out',args=>q[-e'FMT/GT="0/2"' -s XX -m+x],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.8.out',args=>q[-i'FMT/GT="0/0" && AC[*]=2'],fmt=>'%POS\\t%AC[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.8.out',args=>q[-i'AC[*]=2 && FMT/GT="0/0"'],fmt=>'%POS\\t%AC[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.9.out',args=>q[-i'ALT="."'],fmt=>'%POS\\t%AC[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.4',out=>'filter.10.out',args=>q[-S . -i 'FORMAT/TEST3<25']); run_test(\&test_vcf_filter,$opts,in=>'filter.4',out=>'filter.10.out',args=>q[-S . -i 'FORMAT/TEST4<25']); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.12.out',args=>q[-i'GT="A"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.13.out',args=>q[-i'GT="RR"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.14.out',args=>q[-i'GT="RA"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.14.out',args=>q[-i'GT="AR"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.15.out',args=>q[-i'GT="AA"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.16.out',args=>q[-i'GT="aA"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.16.out',args=>q[-i'GT="Aa"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.17.out',args=>q[-i'GT="HOM"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.18.out',args=>q[-i'GT="HET"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.19.out',args=>q[-i'GT="HAP"'],fmt=>'%POS[\\t%GT]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.20.out',args=>q[-i'AD[:1]=11'],fmt=>'%POS[\\t%AD]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.21.out',args=>q[-i'AD[1:]=11'],fmt=>'%POS[\\t%AD]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.22.out',args=>q[-i'FR[0:1]=11'],fmt=>'%POS[\\t%FR]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.23.out',args=>q[-i'AD[*]="."'],fmt=>'%POS[\\t%AD]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.24.out',args=>q[-i'AD[0:0]=="."'],fmt=>'%POS[\\t%AD]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.25.out',args=>q[-i'AD[0:0]!="."'],fmt=>'%POS[\\t%AD]\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.5',out=>'filter.26.out',args=>q[-i'QUAL=="."'],fmt=>'%POS\\t%QUAL\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.27.out',args=>q[-i'N_PASS(DP>32)=1'],fmt=>'[%POS\\t%SAMPLE\\t%DP\\n]'); run_test(\&test_vcf_filter,$opts,in=>'filter.2',out=>'filter.27.out',args=>q[-i'F_PASS(DP>32)=0.5'],fmt=>'[%POS\\t%SAMPLE\\t%DP\\n]'); run_test(\&test_vcf_filter,$opts,in=>'filter.6',out=>'filter.28.out',args=>q[-i'F_MISSING>=1/5'],fmt=>'%POS\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.6',out=>'filter.28.out',args=>q[-i'F_MISSING>=0.2'],fmt=>'%POS\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.6',out=>'filter.28.out',args=>q[-i'F_PASS(GT=="mis")>=1/5'],fmt=>'%POS\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.6',out=>'filter.28.out',args=>q[-i'F_PASS(GT=="mis")>=0.2'],fmt=>'%POS\\n'); run_test(\&test_vcf_filter,$opts,in=>'filter.7',out=>'filter.29.out',args=>'-mx -s + -g2:mnp,indel,other'); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'FORMAT/AO==4']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'MAX(FORMAT/AO[0:])==4']); # although not desired, this is how MAX() works run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.31.out',args=>q[-S . -e 'MAX(FORMAT/AO)==4']); # ( matches the desired sample but selects all samples, as opposed to SMPL_MAX) run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'MIN(FORMAT/AO[0:])==3']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'MIN(FORMAT/AO)==2']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'MIN(FORMAT/AO[0:])==3']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'AVG(FORMAT/AO[2:])==4']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'MEDIAN(FORMAT/AO[2:])==4']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'STDEV(FORMAT/AO[0:])=0.5']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.30.out',args=>q[-S . -e 'SUM(FORMAT/AO[0:])=7']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.32.out',args=>q[-S . -e 'SMPL_MAX(FORMAT/AO)==4']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.33.out',args=>q[-S . -e 'sMIN(FORMAT/AO)==2']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.33.out',args=>q[-S . -e 'ABS(sAVG(FORMAT/AO)-3.66666)<1e-5']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.34.out',args=>q[-S . -e 'sMEDIAN(FORMAT/AO)==4']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.33.out',args=>q[-S . -e 'ABS(sSTDEV(FORMAT/AO)-1.2472191)<1e-5']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.33.out',args=>q[-S . -e 'sSUM(FORMAT/AO)==11']); run_test(\&test_vcf_filter,$opts,in=>'filter.9',out=>'filter.35.out',args=>q[-i 'QUAL/FMT/AD==55']); run_test(\&test_vcf_filter,$opts,in=>'filter.9',out=>'filter.35.out',args=>q[-i 'QUAL/INFO/AD==10']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.36.out',args=>q[-S . -e 'ABS(SMPL_MAX(FORMAT/AO))=5']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.37.out',args=>q[-S . -e 'PHRED(AO[1:])>-4']); run_test(\&test_vcf_filter,$opts,in=>'filter.8',out=>'filter.37.out',args=>q[-S . -e 'ABS(AO[1:])==2']); run_test(\&test_vcf_filter,$opts,in=>'filter.10',out=>'filter.38.out',args=>q[-i 'sum(AD[*]) > FORMAT/DP']); run_test(\&test_vcf_filter,$opts,in=>'filter.10',out=>'filter.38.out',args=>q[-i 'FORMAT/DP < sum(AD[*])']); run_test(\&test_vcf_filter,$opts,in=>'filter.10',out=>'filter.39.out',args=>q[-i 'sum(AD[*]) < FORMAT/DP']); run_test(\&test_vcf_filter,$opts,in=>'filter.10',out=>'filter.39.out',args=>q[-i 'FORMAT/DP > sum(AD[*])']); run_test(\&test_vcf_filter,$opts,in=>'filter.1',out=>'filter.40.out',args=>q[--soft-filter xxx --mask 2:1005-1008 --mask-overlap 0]); run_test(\&test_vcf_filter,$opts,in=>'filter.1',out=>'filter.41.out',args=>q[--soft-filter xxx --mask 2:1005-1008 --mask-overlap 1]); run_test(\&test_vcf_filter,$opts,in=>'filter.1',out=>'filter.42.out',args=>q[--soft-filter xxx --mask 2:1005-1008 --mask-overlap 2]); run_test(\&test_vcf_filter,$opts,in=>'filter.1',out=>'filter.43.out',args=>q[--soft-filter xxx --mask ^2:1005-1008]); run_test(\&test_vcf_sort,$opts,in=>'sort',out=>'sort.out',args=>q[-m 0],fmt=>'%CHROM\\t%POS\\t%REF,%ALT\\n'); run_test(\&test_vcf_sort,$opts,in=>'sort',out=>'sort.out',args=>q[-m 1000],fmt=>'%CHROM\\t%POS\\t%REF,%ALT\\n'); run_test(\&test_vcf_regions,$opts,in=>'regions'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.escape.1',tab=>'annotate.escape.1',out=>'annotate.escape.1.1.out',args=>q[-c CHROM,POS,ISTR,FMT/FSTR]); run_test(\&test_vcf_annotate,$opts,in=>'annotate.match.1',tab=>'annotate.match.1',out=>'annotate.match.1.1.out',args=>q[-c CHROM,POS,-,-,SCORE,~X,-,- -i'STR={X}']); run_test(\&test_vcf_annotate,$opts,in=>'annotate.match.1',tab=>'annotate.match.1',out=>'annotate.match.1.2.out',args=>q[-c CHROM,POS,REF,ALT,SCORE,-,~X,- -i'INT={X}']); run_test(\&test_vcf_annotate,$opts,in=>'annotate.match.1',tab=>'annotate.match.1',out=>'annotate.match.1.2.out',args=>q[-c CHROM,POS,REF,ALT,SCORE,-,-,~X -i'FLT={X}']); run_test(\&test_vcf_annotate,$opts,in=>'annotate',tab=>'annotate',out=>'annotate.out',args=>'-c CHROM,POS,REF,ALT,ID,QUAL,INFO/T_INT,INFO/T_FLOAT,INDEL'); run_test(\&test_vcf_annotate,$opts,in=>'annotate',tab=>'annotate2',out=>'annotate2.out',args=>'-c CHROM,POS,-,T_STR'); run_test(\&test_vcf_annotate,$opts,in=>'annotate',tab=>'annotate2',out=>'annotate22.out',args=>'-c CHROM,FROM,TO,T_STR'); run_test(\&test_vcf_annotate,$opts,in=>'annotate',vcf=>'annots',out=>'annotate3.out',args=>'-c STR,ID,QUAL,FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate4.out',args=>'-c ID,QUAL,FILTER,INFO,FMT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate5.out',args=>'-c ID,QUAL,+FILTER,+INFO,FMT/GT -s A'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate18.out',args=>'-c ID,QUAL,+FILTER,+INFO,FMT/GT -s "A B"'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate19.out',args=>'-c ID,QUAL,+FILTER,+INFO,FMT/GT -s "A C"'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate20.out',args=>'-c ID,QUAL,+FILTER,+INFO,FMT/GT -s "B C"'); run_test(\&test_vcf_annotate,$opts,in=>'annotate3',out=>'annotate6.out',args=>'-x ID,QUAL,^FILTER/fltA,FILTER/fltB,^INFO/AA,INFO/BB,^FMT/GT,FMT/PL'); run_test(\&test_vcf_annotate,$opts,in=>'annotate3',out=>'annotate7.out',args=>'-x FORMAT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate4',vcf=>'annots4',out=>'annotate8.out',args=>'-c +INFO'); run_test(\&test_vcf_annotate,$opts,in=>'annotate4',tab=>'annots4',out=>'annotate8.out',args=>'-c CHROM,POS,REF,ALT,+FA,+FR,+IA,+IR,+SA,+SR'); run_test(\&test_vcf_annotate,$opts,in=>'annotate10',tab=>'annots10',out=>'annotate10.out',args=>'-c CHROM,POS,FMT/FINT,FMT/FFLT,FMT/FSTR'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate11.out',args=>'-c CHROM,POS,FMT/FINT,FMT/FFLT,FMT/FSTR -s A'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',tab=>'annots11',out=>'annotate11.out',args=>'-c CHROM,POS,FMT/FINT,FMT/FFLT,FMT/FSTR -s A'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate12.out',args=>'-c AAA:=IINT,FMT/BBB:=FMT/FINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate13.out',args=>'-x INFO -c INFO/IINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate14.out',args=>q[-x INFO -c INFO/IINT -e'POS=3000001' -k]); run_test(\&test_vcf_annotate,$opts,in=>'annotate11',vcf=>'annots11',out=>'annotate15.out',args=>q[-c FMT]); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots2',out=>'annotate16.out',args=>'-c FMT/newGT:=GT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate2',vcf=>'annots12',out=>'annotate17.out',args=>'-c FMT/GT:=newGT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate13',tab=>'annots13',out=>'annotate21.out',args=>'-c CHROM,BEG,END,ABC'); run_test(\&test_vcf_annotate,$opts,in=>'annotate13',tab=>'annots13',out=>'annotate23.out',args=>'-c CHROM,BEG,END,ABC -l ABC:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate13',tab=>'annots13',out=>'annotate24.out',args=>'-c CHROM,BEG,END,ABC -l ABC:unique'); run_test(\&test_vcf_annotate,$opts,in=>'annotate14',out=>'annotate25.out',args=>'-x FILTER/XX,INFO/XX --force'); run_test(\&test_vcf_annotate,$opts,in=>'annotate15',tab=>'annotate15',out=>'annotate26.out',args=>'-s SAMPLE1 -c CHROM,FROM,TO,FMT/FOO,BAR'); run_test(\&test_vcf_annotate,$opts,in=>'annotate15',tab=>'annotate15',out=>'annotate27.out',args=>'-s SAMPLE2 -c CHROM,FROM,TO,FMT/FOO,BAR'); run_test(\&test_vcf_annotate,$opts,in=>'annotate15',tab=>'annotate15',out=>'annotate27.out',args=>q[-s SAMPLE2 -c CHROM,FROM,TO,FMT/FOO,BAR -H '##FORMAT=' -H '##INFO=']); run_test(\&test_vcf_annotate,$opts,in=>'annotate16',out=>'annotate28.out',args=>'-x FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate17.1',tab=>'annotate17.1',out=>'annotate17.1.out',args=>'-c CHROM,BEG,END,A,B -l A:append,B:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate17.2',tab=>'annotate17.1',out=>'annotate17.2.out',args=>'-c CHROM,BEG,END,A,B -l A:append,B:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate17.3',tab=>'annotate17.3',out=>'annotate17.3.out',args=>'-c CHROM,BEG,END,A,B -l A:append,B:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate18.1',tab=>'annotate18.1',out=>'annotate18.1.out',args=>'-c CHROM,BEG,END,A,B,C,D,E -l A:sum,B:avg,C:min,D:max,E:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate18.2',tab=>'annotate18.2',out=>'annotate18.2.out',args=>'-c CHROM,BEG,END,A,B,C,D,E -l A:sum,B:avg,C:min,D:max,E:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.1.out',args=>'-c INFO/ID:=ID,INFO/INFO_ID:=INFO/ID,ID,=ID:=INFO/ID'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.2.out',args=>'-c FILTER,INFO/FILTER:=FILTER,INFO/INFO_FILTER:=INFO/FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.3.out',args=>'-c INFO/FILTER:=FILTER,INFO/INFO_FILTER:=INFO/FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst', out=>'annotate19.4.out',args=>'-c INFO/FILTER:=FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.5.out',args=>'-c INFO/FILTER:=FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.4.out',args=>'-c INFO/FILTER:=./FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.6.out',args=>'-c INFO/FILTER:=./FILTER,FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate19.dst',vcf=>'annotate19.src',out=>'annotate19.7.out',args=>'-c FILTER,INFO/FILTER:=./FILTER'); run_test(\&test_vcf_annotate,$opts,in=>'annotate20.dst',vcf=>'annotate20.src',out=>'annotate20.1.out',args=>'-c FMT/GT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate20.dst',vcf=>'annotate20.src',out=>'annotate20.2.out',args=>'-c +FMT/GT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate20.dst',vcf=>'annotate20.src',out=>'annotate20.3.out',args=>'-c -FMT/GT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.multi',tab=>'annotate.multi',out=>'annotate.multi.1.out',args=>'-c CHROM,POS,REF,ALT,ANN -l ANN:append'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing-append',tab=>'annotate.missing-append',out=>'annotate.missing-append.1.out',args=>'-c CHROM,POS,REF,ALT,STR,INT,FLT -l STR:append-missing,INT:append-missing,FLT:append-missing'); run_test(\&test_vcf_annotate,$opts,in=>'annotate9',tab=>'annots9',out=>'annotate9.out',args=>'-c CHROM,POS,REF,ALT,+ID'); run_test(\&test_vcf_annotate,$opts,in=>'annotate21',out=>'annotate29.out',args=>'--rename-annots {PATH}/annotate21.txt'); run_test(\&test_vcf_annotate,$opts,in=>'annotate21',out=>'annotate29.out',args=>'-c XX:=FORMAT/X-X,YY:=FORMAT/Y-Y,AA:=FORMAT/A-A,AA:=INFO/A-A,BB:=INFO/B-B,XX:=INFO/X-X,YY:=INFO/Y-Y,fltA:=FILTER/flt-A,fltB:=FILTER/flt-B,fltX:=FILTER/flt-X,fltY:=FILTER/flt-Y'); run_test(\&test_vcf_annotate,$opts,in=>'annotate22',vcf=>'annotate22',out=>'annotate30.out',args=>'-c FMT/XX,INFO/XX -x FMT/XX,INFO/XX'); run_test(\&test_vcf_annotate,$opts,in=>'annotate23',tab=>'annotate23',out=>'annotate31.out',args=>'-c CHROM,POS,~ID,REF,ALT,INFO/END'); run_test(\&test_vcf_annotate,$opts,in=>'annotate24.dst',vcf=>'annotate24.src',out=>'annotate24.1.out',args=>'-c XX'); run_test(\&test_vcf_annotate,$opts,in=>'annotate25',tab=>'annotate25',out=>'annotate25.1.out',args=>'-c CHROM,POS,ID,REF,ALT,~INFO/END'); run_test(\&test_vcf_annotate,$opts,in=>'annotate26',tab=>'annotate26',out=>'annotate26.1.out',args=>'-c CHROM,POS,-POS'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing',tab=>'annotate.missing',out=>'annotate.missing.1.out',args=>'-c CHROM,POS,REF,ALT,TSTR,TFLT,TINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing',tab=>'annotate.missing',out=>'annotate.missing.2.out',args=>'-c CHROM,POS,REF,ALT,.TSTR,.TFLT,.TINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing',tab=>'annotate.missing',out=>'annotate.missing.3.out',args=>'-c CHROM,POS,REF,ALT,.+TSTR,.+TFLT,.+TINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing',tab=>'annotate.missing',out=>'annotate.missing.4.out',args=>'-c CHROM,POS,REF,ALT,+TSTR,+TFLT,+TINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing',tab=>'annotate.missing',out=>'annotate.missing.5.out',args=>'-c CHROM,POS,REF,ALT,.=TSTR,.=TFLT,.=TINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.missing',tab=>'annotate.missing',out=>'annotate.missing.6.out',args=>'-c CHROM,POS,REF,ALT,=TSTR,=TFLT,=TINT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.olap',tab=>'annots.olap',out=>'annotate.olap.1.out',args=>'-c CHROM,BEG,END,DB -l DB:unique'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.olap',tab=>'annots.olap',out=>'annotate.olap.2.out',args=>'-c CHROM,BEG,END,DB -l DB:unique --min-overlap 0.4:0.5 -m XXX'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.id',vcf=>'annots.id',out=>'annotate.id.1.out',args=>'-c ALT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.id',vcf=>'annots.id',out=>'annotate.id.2.out',args=>'-c +ALT'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.id.2',vcf=>'annots.id.2',out=>'annotate.id.2.1.out',args=>'--pair-logic some -c +ID'); run_test(\&test_vcf_annotate,$opts,in=>'annotate.id.2',vcf=>'annots.id.2',out=>'annotate.id.2.2.out',args=>'--pair-logic any -c +ID'); run_test(\&test_vcf_annotate,$opts,in=>'annotate27',tab=>'annotate27',out=>'annotate.32.out',args=>'-c CHROM,POS,REF,ALT,EVIDENCE'); run_test(\&test_vcf_annotate,$opts,in=>'annotate28',tab=>'annots28',out=>'annotate28.1.out',args=>'-c CHROM,POS,REF,ALT,FMT/TEST -s smpl1,smpl2'); run_test(\&test_vcf_annotate,$opts,in=>'annotate28',tab=>'annots28',out=>'annotate28.2.out',args=>'-c CHROM,POS,REF,ALT,FMT/TEST -s smpl2,smpl1'); run_test(\&test_vcf_annotate,$opts,in=>'annotate28',tab=>'annots28',out=>'annotate28.3.out',args=>'-c CHROM,POS,REF,ALT,FMT/TEST -s smpl1'); run_test(\&test_vcf_annotate,$opts,in=>'annotate28',tab=>'annots28',out=>'annotate28.4.out',args=>'-c CHROM,POS,REF,ALT,FMT/TEST -s smpl2'); run_test(\&test_vcf_annotate,$opts,in=>'annotate',out=>'annotate.33.out',args=>'-m XXX'); run_test(\&test_vcf_annotate,$opts,in=>'annotate34',tab=>'annots34',out=>'annotate34.out',args=>q[-c CHROM,FROM,TO,INFO/END -H '##INFO=']); run_test(\&test_vcf_annotate,$opts,in=>'annots-mark',bed=>'annots-mark',out=>'annots-mark.1.out',args=>q[-c CHROM,FROM,TO -m TAG]); run_test(\&test_vcf_plugin,$opts,in=>'checkploidy',out=>'checkploidy.out',cmd=>'+check-ploidy --no-version'); run_test(\&test_vcf_plugin,$opts,in=>'checkploidy.2',out=>'checkploidy.2.out',cmd=>'+check-ploidy --no-version'); run_test(\&test_vcf_plugin,$opts,in=>'checkploidy.2',out=>'checkploidy.3.out',cmd=>'+check-ploidy --no-version',args=>'-- -m'); run_test(\&test_vcf_plugin,$opts,in=>'plugin1',out=>'missing2ref.out',cmd=>'+missing2ref --no-version'); run_test(\&test_vcf_plugin,$opts,in=>'plugin1',out=>'missing2ref.out',cmd=>'+setGT --no-version',args=>'-- -t . -n 0'); run_test(\&test_vcf_plugin,$opts,in=>'setGT',out=>'setGT.1.out',cmd=>'+setGT --no-version',args=>'-- -t q -n 0 -i \'GT~"." && FMT/DP=30 && GQ=150\''); run_test(\&test_vcf_plugin,$opts,in=>'setGT.2',out=>'setGT.2.out',cmd=>'+setGT --no-version',args=>'-- -t q -n . -i \'GT[@{QPATH}/setGT.samples.txt]="het"\''); run_test(\&test_vcf_plugin,$opts,in=>'setGT.2',out=>'setGT.3.out',cmd=>'+setGT --no-version',args=>'-- -t q -n . -i \'GT[@{QPATH}/setGT.samples.txt]="het" & binom(AD[@{QPATH}/setGT.samples.txt])<0.1\''); run_test(\&test_vcf_plugin,$opts,in=>'setGT.3',out=>'setGT.3.1.out',cmd=>'+setGT --no-version',args=>'-- -t a -n pM'); run_test(\&test_vcf_plugin,$opts,in=>'setGT.3',out=>'setGT.3.2.out',cmd=>'+setGT --no-version',args=>'-- -t a -n pm'); run_test(\&test_vcf_plugin,$opts,in=>'setGT.3',out=>'setGT.3.3.out',cmd=>'+setGT --no-version',args=>'-- -t a -n c:1'); run_test(\&test_vcf_plugin,$opts,in=>'setGT.3',out=>'setGT.3.4.out',cmd=>'+setGT --no-version',args=>'-- -t a -n c:"1|1"'); run_test(\&test_vcf_plugin,$opts,in=>'setGT.3',out=>'setGT.3.5.out',cmd=>'+setGT --no-version',args=>'-- -t a -n c:"m|M"'); run_test(\&test_vcf_plugin,$opts,in=>'setGT.3',out=>'setGT.3.6.out',cmd=>'+setGT --no-version',args=>'-- -t a -n c:0/1/1'); run_test(\&test_vcf_plugin,$opts,in=>'setGT.4',out=>'setGT.4.1.out',cmd=>'+setGT --no-version',args=>q[-- -t q -n . -e 'FMT/DP>90']); run_test(\&test_vcf_plugin,$opts,in=>'setGT.4',out=>'setGT.4.2.out',cmd=>'+setGT --no-version',args=>q[-- -t q -n . -e 'FMT/DP>100']); run_test(\&test_vcf_plugin,$opts,in=>'setGT.5',out=>'setGT.5.1.out',cmd=>'+setGT --no-version',args=>q[-- -t a -n X]); run_test(\&test_vcf_plugin,$opts,in=>'setGT.5',out=>'setGT.5.2.out',cmd=>'+setGT --no-version',args=>q[-- -t a -n c:0/X/X]); run_test(\&test_vcf_plugin,$opts,in=>'setGT.6',out=>'setGT.6.1.out',cmd=>'+setGT --no-version',args=>q[-- -t ./x -n .]); run_test(\&test_vcf_plugin,$opts,in=>'setGT.6',out=>'setGT.6.1.out',cmd=>'+setGT --no-version',args=>q[-- -t . -n .]); run_test(\&test_vcf_plugin,$opts,in=>'setGT.6',out=>'setGT.6.2.out',cmd=>'+setGT --no-version',args=>q[-- -t r:0.5 -n .]); run_test(\&test_vcf_plugin,$opts,in=>'plugin1',out=>'fill-AN-AC.out',cmd=>'+fill-AN-AC --no-version'); run_test(\&test_vcf_plugin,$opts,in=>'dosage',out=>'dosage.1.out',cmd=>'+dosage',args=>'-- -t PL'); run_test(\&test_vcf_plugin,$opts,in=>'dosage',out=>'dosage.2.out',cmd=>'+dosage',args=>'-- -t GL'); run_test(\&test_vcf_plugin,$opts,in=>'dosage',out=>'dosage.3.out',cmd=>'+dosage',args=>'-- -t GT'); run_test(\&test_vcf_plugin,$opts,in=>'fixploidy',out=>'fixploidy.out',cmd=>'+fixploidy --no-version',args=>'-- -s {PATH}/fixploidy.samples -p {PATH}/fixploidy.ploidy'); run_test(\&test_vcf_plugin,$opts,in=>'view.PL',out=>'guess-ploidy.PL.out',cmd=>'+guess-ploidy',args=>'-vrX | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view.GL',out=>'guess-ploidy.GL.out',cmd=>'+guess-ploidy',args=>'-vrX | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view.GL',out=>'view.PL.vcf',cmd=>'+tag2tag --no-version',args=>'-- -r --gl-to-pl'); run_test(\&test_vcf_plugin,$opts,in=>'view.GL',out=>'view.GL-GP.vcf',cmd=>'+tag2tag --no-version',args=>'-- --gl-to-gp'); run_test(\&test_vcf_plugin,$opts,in=>'view.GP',out=>'view.GT.vcf',cmd=>'+tag2tag --no-version',args=>'-- -r --gp-to-gt -t 0.2'); run_test(\&test_vcf_plugin,$opts,in=>'tag2tag.LPL.1',out=>'tag2tag.LPL.1.1.vcf',cmd=>'+tag2tag --no-version',args=>'-- --LXX-to-XX'); run_test(\&test_vcf_plugin,$opts,in=>'tag2tag.LPL.1',out=>'tag2tag.LPL.1.2.vcf',cmd=>'+tag2tag --no-version',args=>'-- --LXX-to-XX -r'); run_test(\&test_vcf_plugin,$opts,in=>'tag2tag.LPL.1',out=>'tag2tag.LPL.1.3.vcf',cmd=>'+tag2tag --no-version',args=>'-- --LXX-to-XX -r -d AD:0,PL:255 -s 3'); run_test(\&test_vcf_plugin,$opts,in=>'query.variantkey',out=>'query.add-variantkey.vcf',cmd=>'+add-variantkey',args=>''); run_test(\&test_vcf_plugin,$opts,in=>'query.variantkey',out=>'variantkey-hex.out',cmd=>'+variantkey-hex',args=>'test/'); run_test(\&test_vcf_plugin,$opts,in=>'query.nucleotide',out=>'query.allele-length.tsv',cmd=>'+allele-length',args=>''); run_test(\&test_vcf_plugin,$opts,in=>'merge.a',out=>'fill-tags.out',cmd=>'+fill-tags --no-version',args=>'-- -t AN,AC,AC_Hom,AC_Het,AC_Hemi'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'fill-tags.2.out',cmd=>'+fill-tags --no-version',args=>'-- -t AC,AN,AF,MAF,NS'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'fill-tags.3.out',cmd=>'+fill-tags --no-version',args=>'-- -t AC -S {PATH}/fill-tags.3.smpl'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'fill-tags.5.out',cmd=>'+fill-tags --no-version',args=>'-- -t "DP:1=int(sum(FORMAT/DP))" -S {PATH}/fill-tags.3.smpl'); run_test(\&test_vcf_plugin,$opts,in=>'many-alts',out=>'fill-tags.4.out',cmd=>'+fill-tags --no-version',args=>'-- -t AN,AC'); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-hemi',out=>'fill-tags-hemi.1.out',cmd=>'+fill-tags --no-version'); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-hemi',out=>'fill-tags-hemi.2.out',cmd=>'+fill-tags --no-version',args=>'-- -d'); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-hwe',out=>'fill-tags-hwe.out',cmd=>'+fill-tags --no-version'); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-hwe',out=>'fill-tags-func.out',cmd=>'+fill-tags --no-version',args=>q[-- -t 'XX:1=F_PASS(GT="alt")']); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-AN0',out=>'fill-tags-AN0.out',cmd=>'+fill-tags --no-version',args=>'-- -t all,END,TYPE,F_MISSING'); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-VAF',out=>'fill-tags-VAF.out',cmd=>'+fill-tags --no-version',args=>'-- -t VAF,VAF1'); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-AD',out=>'fill-tags-AD.1.out',cmd=>'+fill-tags --no-version',args=>q[-- -t 'INFO/DP:1=int(sum(FMT/AD))']); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-AD',out=>'fill-tags-AD.2.out',cmd=>'+fill-tags --no-version',args=>q[-- -t 'INFO/DP:1=int(sum(INFO/AD))']); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-AD',out=>'fill-tags-AD.3.out',cmd=>'+fill-tags --no-version',args=>q[-- -t 'FORMAT/DP:1=int(smpl_sum(FMT/AD))']); run_test(\&test_vcf_plugin,$opts,in=>'fill-tags-AD',out=>'fill-tags-AD.4.out',cmd=>'+fill-tags --no-version',args=>q[-- -t 'XX=N_PASS(FMT/AD[:0]<=10)','YY=N_PASS(FMT/AD[:0]>10)']); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.out',cmd=>'+GTisec',args=>' | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.H.out',cmd=>'+GTisec',args=>'-- -H | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.Hm.out',cmd=>'+GTisec',args=>'-- -Hm | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.Hmv.out',cmd=>'+GTisec',args=>'-- -Hmv | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.Hv.out',cmd=>'+GTisec',args=>'-- -Hv | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.m.out',cmd=>'+GTisec',args=>'-- -m | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.mv.out',cmd=>'+GTisec',args=>'-- -mv | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTisec.v.out',cmd=>'+GTisec',args=>'-- -v | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'trio',out=>'trio.out',cmd=>'+trio-switch-rate',args=>'-- -p {PATH}/trio.ped | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'trio-stats',out=>'trio-stats.out',cmd=>'+trio-stats',args=>'-a 1 -p {PATH}/trio-stats.ped -d mendel-errors,transmitted | grep -v ^CMD'); run_test(\&test_vcf_plugin,$opts,in=>'trio-stats',out=>'trio-stats.2.out',cmd=>'+trio-stats',args=>'-p {PATH}/trio-stats.ped -d mendel-errors,transmitted | grep -v ^CMD'); run_test(\&test_vcf_plugin,$opts,in=>'indel-stats',out=>'smpl-stats.1.out',cmd=>'+smpl-stats',args=>'| grep -v ^CMD'); run_test(\&test_vcf_plugin,$opts,in=>'indel-stats',out=>'indel-stats.1.out',cmd=>'+indel-stats',args=>'| grep -v ^CMD'); run_test(\&test_vcf_plugin,$opts,in=>'indel-stats',out=>'indel-stats.2.out',cmd=>'+indel-stats',args=>' -p {PATH}/trio-stats.ped | grep -v ^CMD'); run_test(\&test_vcf_plugin,$opts,in=>'indel-stats',out=>'indel-stats.3.out',cmd=>'+indel-stats',args=>' -p {PATH}/trio-stats.2.ped | grep -v ^CMD'); run_test(\&test_vcf_plugin,$opts,in=>'ad-bias',out=>'ad-bias.out',cmd=>'+ad-bias',args=>'-- -s {PATH}/ad-bias.samples | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'ad-bias.2',out=>'ad-bias.out',cmd=>'+ad-bias',args=>'-- -s {PATH}/ad-bias.samples | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'ad-bias',out=>'ad-bias.2.out',cmd=>'+ad-bias',args=>'--no-version -- -s {PATH}/ad-bias.samples -c | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'ad-bias.2',out=>'ad-bias.2.out',cmd=>'+ad-bias',args=>'--no-version -- -s {PATH}/ad-bias.samples -c | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'af-dist',out=>'af-dist.out',cmd=>'+af-dist',args=>' | grep -v bcftools'); run_test(\&test_vcf_plugin,$opts,in=>'fixref.2a',out=>'fixref.2.out',index=>['fixref.2b'],cmd=>'+fixref',args=>'-- -f {PATH}/norm.fa -i {TMP}/fixref.2b.vcf.gz'); run_test(\&test_vcf_plugin,$opts,in=>'fixref.3',out=>'fixref.3.out',cmd=>'+fixref',args=>'-- -f {PATH}/fixref.3.fa -m top'); run_test(\&test_vcf_plugin,$opts,in=>'fixref.2a',out=>'fixref.4.out',index=>['fixref.2b'],cmd=>'+fixref',args=>'-- -f {PATH}/norm.fa -m ref-alt'); run_test(\&test_vcf_plugin,$opts,in=>'fixref.2a',out=>'fixref.5.out',index=>['fixref.2b'],cmd=>'+fixref',args=>'-- -f {PATH}/norm.fa -m flip'); run_test(\&test_vcf_plugin,$opts,in=>'fixref.2a',out=>'fixref.6.out',cmd=>'+fixref',args=>'-- -f {PATH}/norm.fa -m flip-all'); run_test(\&test_vcf_plugin,$opts,in=>'fixref.2a',out=>'fixref.7.out',cmd=>'+fixref',args=>'-- -f {PATH}/norm.fa -m swap'); run_test(\&test_vcf_plugin,$opts,in=>'aa',out=>'aa.out',cmd=>'+fill-from-fasta',args=>'-- -f {PATH}/aa.fa -c AA -h {PATH}/aa.hdr -i \'TYPE="snp"\''); run_test(\&test_vcf_plugin,$opts,in=>'aa',out=>'aa.2.out',cmd=>'+fill-from-fasta',args=>'-- -f {PATH}/aa.fa -c REF -N'); run_test(\&test_vcf_plugin,$opts,in=>'ref',out=>'ref.out',cmd=>'+fill-from-fasta',args=>'-- -f {PATH}/norm.fa -c REF'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTsubset.NA1.out',cmd=>'+GTsubset --no-version',args=>'-- -s NA00001'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTsubset.NA1NA2.out',cmd=>'+GTsubset --no-version',args=>'-- -s NA00001,NA00002'); run_test(\&test_vcf_plugin,$opts,in=>'view',out=>'view.GTsubset.NA1NA2NA3.out',cmd=>'+GTsubset --no-version',args=>'-- -s NA00001,NA00002,NA00003'); run_test(\&test_vcf_plugin,$opts,in=>'mendelian',out=>'mendelian.1.out',cmd=>'+mendelian2',args=>'-p child1,dad1,mom1 -md'); run_test(\&test_vcf_plugin,$opts,in=>'mendelian',out=>'mendelian.6.out',cmd=>'+mendelian2',args=>'-p child1,dad1,mom1 -mg'); run_test(\&test_vcf_plugin,$opts,in=>'mendelian',out=>'mendelian.3.out',cmd=>'+mendelian2',args=>'-p child1,dad1,mom1 -me'); run_test(\&test_vcf_plugin,$opts,in=>'mendelian',out=>'mendelian.4.out',cmd=>'+mendelian2',args=>'-p child1,dad1,mom1 -ma'); run_test(\&test_vcf_plugin,$opts,in=>'mendelian',out=>'mendelian.7.out',cmd=>'+mendelian2',args=>'-p child1,dad1,mom1 -mm'); run_test(\&test_vcf_plugin,$opts,in=>'mendelian',out=>'mendelian.8.out',cmd=>'+mendelian2',args=>'-p child1,dad1,mom1 | grep -v ^#'); run_test(\&test_vcf_plugin,$opts,in=>'contrast',out=>'contrast.out',cmd=>'+contrast',args=>'-a PASSOC,FASSOC,NOVELAL,NOVELGT -0 a,b -1 c'); run_test(\&test_vcf_plugin,$opts,in=>'contrast',out=>'contrast.out',cmd=>'+contrast',args=>'-a PASSOC,FASSOC,NOVELAL,NOVELGT -0 {PATH}/contrast0.txt -1 {PATH}/contrast1.txt'); run_test(\&test_vcf_plugin,$opts,in=>'contrast',out=>'contrast.1.out',cmd=>'+contrast',args=>'-a NASSOC -0 a,b,c -1 d --force-samples'); run_test(\&test_vcf_plugin,$opts,in=>'contrast.1',out=>'contrast.1.1.out',cmd=>'+contrast',args=>'-a NOVELAL,NOVELGT -0 A -1 B'); run_test(\&test_vcf_plugin,$opts,in=>'contrast.1',out=>'contrast.1.2.out',cmd=>'+contrast',args=>'-a NOVELGT -0 A -1 B'); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.1',out=>'trio-dnm/trio-dnm.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --ppl --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.2',out=>'trio-dnm/trio-dnm.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --ppl --dnm-tag DNM:log --force-AD | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.4',out=>'trio-dnm/trio-dnm.4.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --use-DNG | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.4',out=>'trio-dnm/trio-dnm.4.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.4',out=>'trio-dnm/trio-dnm.4.2.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --use-DNG --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.4',out=>'trio-dnm/trio-dnm.4.2.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.5',out=>'trio-dnm/trio-dnm.5.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --use-DNG --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.5',out=>'trio-dnm/trio-dnm.5.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.6',out=>'trio-dnm/trio-dnm.6.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --use-DNG --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); # incorrect miss by DNG run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.6',out=>'trio-dnm/trio-dnm.6.2.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\t[\\t%VA]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.7',out=>'trio-dnm/trio-dnm.7.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --use-DNG --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); # incorrect miss, low PL run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.7',out=>'trio-dnm/trio-dnm.7.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --dnm-tag DNM:log | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.8',out=>'trio-dnm/trio-dnm.8.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother | $$opts{bin}/bcftools query -f'[\\t%DNM]\\t[\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.9',out=>'trio-dnm/trio-dnm.9.1.out',cmd=>'+trio-dnm2',args=>"-p 1X:proband,father,mother --use-NAIVE | $$opts{bin}/bcftools query -f'[\\t%DNM]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.9',out=>'trio-dnm/trio-dnm.9.2.out',cmd=>'+trio-dnm2',args=>"-p 2X:proband,father,mother --use-NAIVE | $$opts{bin}/bcftools query -f'[\\t%DNM]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.10',out=>'trio-dnm/trio-dnm.10.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother --with-pAD | $$opts{bin}/bcftools query -f'[\\t%DNM][\\t%VAF]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.11',out=>'trio-dnm/trio-dnm.11.1.out',cmd=>'+trio-dnm2',args=>"-p proband,father,mother | $$opts{bin}/bcftools query -f'%CHROM:%POS DNM=[%DNM ]\\tAD=[%AD ]\\tQS=[%QS ]\\tVAF=[%VAF ]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'trio-dnm/trio-dnm.11',out=>'trio-dnm/trio-dnm.11.2.out',cmd=>'+trio-dnm2',args=>"-p 1X:proband,father,mother --strictly-novel | $$opts{bin}/bcftools query -f'%CHROM:%POS DNM=[%DNM ]\\tAD=[%AD ]\\tQS=[%QS ]\\tVAF=[%VAF ]\\n'"); run_test(\&test_vcf_plugin,$opts,in=>'gvcfz',out=>'gvcfz.1.out',cmd=>'+gvcfz',args=>qq[-g 'PASS:GT!="alt"' -a | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%END[\\t%GT][\\t%DP][\\t%GQ][\\t%RGQ]\\n']); run_test(\&test_vcf_plugin,$opts,in=>'gvcfz',out=>'gvcfz.2.out',cmd=>'+gvcfz',args=>qq[-g 'PASS:GQ>10; FLT:-' -a | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%FILTER\\t%END[\\t%GT][\\t%DP][\\t%GQ][\\t%RGQ]\\n']); run_test(\&test_vcf_plugin,$opts,in=>'gvcfz.2',out=>'gvcfz.2.1.out',cmd=>'+gvcfz',args=>qq[-g 'PASS:GT!="alt"' -a | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%FILTER\\t%END[\\t%GT][\\t%DP]\\n']); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.1',out=>'remove-overlaps.1.1.out',cmd=>'+remove-overlaps',args=>'-m overlap'); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.1',out=>'remove-overlaps.1.2.out',cmd=>'+remove-overlaps',args=>'-m overlap -M overlap'); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.1',out=>'remove-overlaps.1.3.out',cmd=>'+remove-overlaps',args=>'-m overlap -O t'); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.1',out=>'remove-overlaps.1.4.out',cmd=>'+remove-overlaps',args=>'-m overlap --reverse'); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.1',out=>'remove-overlaps.1.5.out',cmd=>'+remove-overlaps',args=>'-m dup -M DUP'); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.1',out=>'remove-overlaps.1.6.out',cmd=>'+remove-overlaps',args=>'-m dup -M unique --reverse'); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.2',out=>'remove-overlaps.2.1.out',cmd=>'+remove-overlaps',args=>q[-m 'min(QUAL)' -M rmme]); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.3',out=>'remove-overlaps.3.1.out',cmd=>'+remove-overlaps',args=>q[-m 'min(QUAL)' -M rmme]); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.3',out=>'remove-overlaps.3.1.out',cmd=>'+remove-overlaps',args=>q[-m 'min(QUAL)' -M rmme --missing 0]); run_test(\&test_vcf_plugin,$opts,in=>'remove-overlaps.3',out=>'remove-overlaps.3.2.out',cmd=>'+remove-overlaps',args=>q[-m 'min(QUAL)' -M rmme --missing DP]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.1.out',cmd=>'+split-vep',args=>qq[-c Consequence -s worst:missense+ | $$opts{bin}/bcftools query -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.2.out',cmd=>'+split-vep',args=>qq[-c Consequence -s worst:missense+ | $$opts{bin}/bcftools query -f'%POS\\t%Consequence\\n' -i'Consequence!="."']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.2.out',cmd=>'+split-vep',args=>qq[-s worst:missense+ -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.3.out',cmd=>'+split-vep',args=>qq[-s primary:missense+ -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.3.out',cmd=>'+split-vep',args=>qq[-s CANONICAL=YES:missense+ -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.4.out',cmd=>'+split-vep',args=>qq[-s primary:missense+ -f'%POS\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.4.out',cmd=>'+split-vep',args=>qq[-s CANONICAL=YES:missense+ -f'%POS\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.2',out=>'split-vep.5.out',cmd=>'+split-vep',args=>qq[-s worst -f'%POS\\t%AF\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.2',out=>'split-vep.6.out',cmd=>'+split-vep',args=>qq[-s worst -f'%POS\\t%AF\\n' -a BCSQ]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.2',out=>'split-vep.6.out',cmd=>'+split-vep',args=>qq[-s worst -f'%POS\\t%INFO/AF\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.2',out=>'split-vep.6.out',cmd=>'+split-vep',args=>qq[-s worst -f'%POS\\t%INFO/AF\\n' -a BCSQ]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.3',out=>'split-vep.7.out',cmd=>'+split-vep',args=>qq[-s worst -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.3',out=>'split-vep.8.out',cmd=>'+split-vep',args=>qq[-s worst -f'[%POS\\t%SAMPLE\\t%GT\\t%Consequence\\n]' -i'GT="alt"']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.9.out', cmd=>'+split-vep',args=>qq[-t 1:14464 -f '%POS\\t%CANONICAL\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.10.out',cmd=>'+split-vep',args=>qq[-t 1:14464 -f '%POS\\t%CANONICAL\\t%Consequence\\n' -d]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.11.out',cmd=>'+split-vep',args=>qq[-t 1:14464 -f '%POS\\t%CSQ\\n' -A tab]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.12.out',cmd=>'+split-vep',args=>qq[-t 1:14464 -f '%POS\\t%CSQ\\n' -A tab -d]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.12.2.out',cmd=>'+split-vep',args=>qq[-t 1:14464 -f '%POS\\t%CSQ\\n' -A tab -d -H]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.12.3.out',cmd=>'+split-vep',args=>qq[-t 1:14464 -f '%POS\\t%CSQ\\n' -A tab -d -HH]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.4',out=>'split-vep.13.out',cmd=>'+split-vep',args=>qq[-f '%POS\\t%BCSQ\\n' -a BCSQ -A tab -d]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.4',out=>'split-vep.13.out',cmd=>'+split-vep',args=>qq[-f '%POS\\t%BCSQ\\n' -A tab -d]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.14.out',cmd=>'+split-vep',args=>qq[-c gnomAD_NFE_AF:real,ALLELE_NUM:int | $$opts{bin}/bcftools query -f'%POS\\t%gnomAD_NFE_AF\\t%ALLELE_NUM\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.14.out',cmd=>'+split-vep',args=>qq[-c gnomAD_NFE_AF,ALLELE_NUM | $$opts{bin}/bcftools query -f'%POS\\t%gnomAD_NFE_AF\\t%ALLELE_NUM\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.5',out=>'split-vep.15.out',cmd=>'+split-vep',args=>qq[-s :synonymous -c Consequence | $$opts{bin}/bcftools query -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.5',out=>'split-vep.16.out',cmd=>'+split-vep',args=>qq[-s :synonymous -x -c Consequence | $$opts{bin}/bcftools query -f'%POS\\t%Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.6',out=>'split-vep.17.out',cmd=>'+split-vep',args=>qq[-c SAS_AF | grep ID=SAS_AF]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.6',out=>'split-vep.18.out',cmd=>'+split-vep',args=>qq[-c - | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.6',out=>'split-vep.19.out',cmd=>'+split-vep',args=>qq[-c - -s worst | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.7',out=>'split-vep.20.out',cmd=>'+split-vep',args=>qq[--annotation 'ANN' -c IMPACT -i 'INFO/IMPACT[*] ~ "MODIFIER"' | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.8',out=>'split-vep.21.out',cmd=>'+split-vep',args=>qq[-a BCSQ -s worst -c Consequence,amino_acid_change,BCSQ | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.8',out=>'split-vep.21.out',cmd=>'+split-vep',args=>qq[ -s worst -c Consequence,amino_acid_change,BCSQ | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.8',out=>'split-vep.22.out',cmd=>'+split-vep',args=>qq[-a BCSQ -s worst -f '%POS\\t%Consequence\\t%amino_acid_change\\t%BCSQ\\n' | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.8',out=>'split-vep.22.out',cmd=>'+split-vep',args=>qq[ -s worst -f '%POS\\t%Consequence\\t%amino_acid_change\\t%BCSQ\\n' | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.9',out=>'split-vep.23.out',cmd=>'+split-vep',args=>qq[-a BCSQ -f '%CHROM\\t%POS\\t%REF\\t%ALT\\t%BCSQ\\n' -d -A tab | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.9',out=>'split-vep.24.out',cmd=>'+split-vep',args=>qq[-a BCSQ -f '%xPOS %xConsequence\\n' -p x | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.10',out=>'split-vep.25.out',cmd=>'+split-vep',args=>qq[-a CSQ -f '%M_CAP_pred %M_CAP_score\\n' | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.10',out=>'split-vep.25.out',cmd=>'+split-vep',args=>qq[-a CSQ -f '%xM_CAP_pred %xM_CAP_score\\n' -p x | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.10',out=>'split-vep.25.out',cmd=>'+split-vep',args=>qq[ -f '%xM_CAP_pred %xM_CAP_score\\n' -p x | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.gene-list',out=>'split-vep.gene-list.1.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %Gene %Consequence\\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.gene-list',out=>'split-vep.gene-list.2.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %Gene %Consequence\\n' -g {PATH}/split-vep.gene-list.txt]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.gene-list',out=>'split-vep.gene-list.2.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %Gene %Consequence\\n' -g {PATH}/split-vep.mixed-list.txt --gene-list-fields Feature,SYMBOL]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.gene-list',out=>'split-vep.gene-list.3.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %Gene %Consequence\\n' -g +{PATH}/split-vep.gene-list.txt]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.gene-list',out=>'split-vep.gene-list.3.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %Gene %Consequence\\n' -g +{PATH}/split-vep.mixed-list.txt --gene-list-fields Feature,SYMBOL]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.broken-LoF',out=>'split-vep.broken-LoF.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %Consequence %LoF_info\\n' -a vep]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.broken-LoF',out=>'split-vep.broken-LoF.2.out',cmd=>'+split-vep',args=>qq[-d -f '%CHROM:%POS %LoF_info\\n' -a vep -i 'Consequence=="frameshift_variant"']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.26.out',cmd=>'+split-vep',args=>qq[-f'%POS\\n' -i'SYMBOL~"SAMD11"']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep',out=>'split-vep.27.out',cmd=>'+split-vep',args=>qq[-f'%POS\\t%MAX_AF\\n' -i'MAX_AF>0.999' -c MAX_AF,MAX_AF:float,MAX_AF]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.filter',out=>'split-vep.filter.1.out',cmd=>'+split-vep',args=>qq[-s worst -i'CSQ~"nonsense"' -f '%POS %Consequence %Feature %BIOTYPE']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.filter',out=>'split-vep.filter.2.out',cmd=>'+split-vep',args=>qq[-s worst -i'CSQ~"nonsense"' -f '%POS %Consequence %Feature %BIOTYPE %CSQ']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.1.out',cmd=>'+split-vep',args=>qq[-f '%POS %CANONICAL %MANE_SELECT %Consequence' -s primary]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.1.out',cmd=>'+split-vep',args=>qq[-f '%POS %CANONICAL %MANE_SELECT %Consequence' -s CANONICAL=YES]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.2.out',cmd=>'+split-vep',args=>qq[-f '%POS %CANONICAL %MANE_SELECT %Consequence' -s CANONICAL!=YES]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.2.out',cmd=>'+split-vep',args=>qq[-f '%POS %CANONICAL %MANE_SELECT %Consequence' -s CANONICAL=]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.1.out',cmd=>'+split-vep',args=>qq[-f '%POS %CANONICAL %MANE_SELECT %Consequence' -s mane]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.1.out',cmd=>'+split-vep',args=>qq[-f '%POS %CANONICAL %MANE_SELECT %Consequence' -s MANE_SELECT!='']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.3.out',cmd=>'+split-vep',args=>qq[-s mane]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.3.out',cmd=>'+split-vep',args=>qq[-s primary]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.select-tr-expr',out=>'select-tr-expr.3.out',cmd=>'+split-vep',args=>qq[-s PolyPhen~damaging]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.types',out=>'split-vep.types.1.out',cmd=>'+split-vep',args=>qq[-f'%cDNA_position %CDS_position %Protein_position']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.types',out=>'split-vep.types.2.out',cmd=>'+split-vep',args=>qq[-f'%cDNA_position %CDS_position %Protein_position' -c cDNA_position:int,CDS_position:int,Protein_position:int]); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.filter-missing-bt2098',out=>'split-vep.filter-missing-bt2098.1.out',cmd=>'+split-vep',args=>qq[-e 'gnomad_genomes_AF >= 0.02' | $$opts{bin}/bcftools query -f'%CHROM %POS \t %gnomad_genomes_AF\n']); run_test(\&test_vcf_plugin,$opts,in=>'split-vep.filter-missing-bt2098',out=>'split-vep.filter-missing-bt2098.1.out',cmd=>'+split-vep',args=>qq[-i 'gnomad_genomes_AF < 0.02 || gnomad_genomes_AF=="."' | $$opts{bin}/bcftools query -f'%CHROM %POS \t %gnomad_genomes_AF\n']); run_test(\&test_vcf_plugin,$opts,in=>'parental-origin',out=>'parental-origin.1.out',cmd=>'+parental-origin',args=>qq[-r 20:100 -p proband,father,mother -t del | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'parental-origin',out=>'parental-origin.2.out',cmd=>'+parental-origin',args=>qq[-r 20:101 -p proband,father,mother -t del | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'parental-origin',out=>'parental-origin.3.out',cmd=>'+parental-origin',args=>qq[-r 20:102 -p proband,father,mother -t del | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'parental-origin',out=>'parental-origin.4.out',cmd=>'+parental-origin',args=>qq[-r 20:103 -p proband,father,mother -t dup | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'parental-origin',out=>'parental-origin.5.out',cmd=>'+parental-origin',args=>qq[-r 20:104 -p proband,father,mother -t dup | grep -v ^#]); run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.1.out',cmd=>'+prune -w 1 -a r2,LD,HD'); # annotate with r2,LD,HD at the previous site run_test(\&test_vcf_plugin,$opts,in=>'prune.2',out=>'prune.2.1.out',cmd=>'+prune -w 1 -a r2,LD,HD'); run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.2.out',cmd=>'+prune -w 2 -a r2 -m 0.5 -f MaxR2'); # prune within 2bp, max r2=0.5, soft filter run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.3.out',cmd=>'+prune -w 2 -a r2 -m 0.5 '); # prune within 2bp, max r2=0.5 run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.4.out',cmd=>'+prune -w 2bp -n 1 --AF-tag AF'); # leave 1 site within 2bp windows, prioritize by AF run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.5.out',cmd=>q[+prune -w 2bp -n 1 --AF-tag AF -i 'GT="alt"']); # same as above but first discard REF-only sites run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.6.out',cmd=>'+prune -w 2bp -n 1 -N 1st'); run_test(\&test_vcf_plugin,$opts,in=>'prune.1',out=>'prune.1.7.out',cmd=>'+prune -w 2bp -n 1 -N rand --random-seed 1'); run_test(\&test_vcf_plugin,$opts,in=>'variant-distance',out=>'variant-distance.1.out',cmd=>'+variant-distance'); run_test(\&test_vcf_plugin,$opts,in=>'variant-distance',out=>'variant-distance.1.out',cmd=>'+variant-distance -d nearest'); run_test(\&test_vcf_plugin,$opts,in=>'variant-distance',out=>'variant-distance.2.out',cmd=>'+variant-distance -d fwd'); run_test(\&test_vcf_plugin,$opts,in=>'variant-distance',out=>'variant-distance.3.out',cmd=>'+variant-distance -d rev'); run_test(\&test_vcf_plugin,$opts,in=>'variant-distance',out=>'variant-distance.4.out',cmd=>'+variant-distance -d both'); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.1.out',tmp=>'split.1.1'); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.2.out',tmp=>'split.1.2',args=>'-S {PATH}/split.smpl.1.2.txt'); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.3.out',tmp=>'split.1.3',args=>'-S {PATH}/split.smpl.1.3.txt'); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.4.out',tmp=>'split.1.4',args=>q[-S {PATH}/split.smpl.1.3.txt -i 'GT[0]="alt"']); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.5.out',tmp=>'split.1.5',args=>q[-S {PATH}/split.smpl.1.3.txt -i 'GT="alt"']); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.6.out',tmp=>'split.1.6',args=>q[-S {PATH}/split.smpl.1.4.txt -i 'GT="alt"']); run_test(\&test_plugin_split,$opts,in=>'split.1',out=>'split.1.7.out',tmp=>'split.1.7',args=>q[-G {PATH}/split.grp.1.1.txt]); run_test(\&test_plugin_split,$opts,in=>'split.2',out=>'split.2.1.out',tmp=>'split.2.1',args=>q[]); run_test(\&test_plugin_scatter,$opts,in=>'scatter.1',out=>'scatter.1.1.out',tmp=>'scatter.1.1',args=>q[-n 3]); run_test(\&test_plugin_scatter,$opts,in=>'scatter.1',out=>'scatter.1.2.out',tmp=>'scatter.1.2',args=>q[-s 21,22]); run_test(\&test_plugin_scatter,$opts,in=>'scatter.1',out=>'scatter.1.3.out',tmp=>'scatter.1.3',args=>q[-s 21,22 -x X]); run_test(\&test_vcf_concat,$opts,in=>['concat.1.a','concat.1.b'],out=>'concat.1.vcf.out',do_bcf=>0,args=>''); run_test(\&test_vcf_concat,$opts,in=>['concat.1.a','concat.1.b'],out=>'concat.1.bcf.out',do_bcf=>1,args=>''); run_test(\&test_vcf_concat,$opts,in=>['concat.2.a','concat.2.b'],out=>'concat.2.vcf.out',do_bcf=>0,args=>'-a'); run_test(\&test_vcf_concat,$opts,in=>['concat.2.a','concat.2.b'],out=>'concat.2.bcf.out',do_bcf=>1,args=>'-a'); run_test(\&test_vcf_concat,$opts,in=>['concat.2.a','concat.2.b'],out=>'concat.4.vcf.out',do_bcf=>0,args=>'-aD'); run_test(\&test_vcf_concat,$opts,in=>['concat.2.a','concat.2.b'],out=>'concat.4.bcf.out',do_bcf=>1,args=>'-aD'); run_test(\&test_vcf_concat,$opts,in=>['concat.3.a','concat.3.b','concat.3.0','concat.3.c','concat.3.d','concat.3.e','concat.3.f'],out=>'concat.3.vcf.out',do_bcf=>0,args=>'-l --ligate-warn'); run_test(\&test_vcf_concat,$opts,in=>['concat.3.a','concat.3.b','concat.3.0','concat.3.c','concat.3.d','concat.3.e','concat.3.f'],out=>'concat.3.bcf.out',do_bcf=>1,args=>'-l --ligate-warn'); run_test(\&test_naive_concat,$opts,name=>'naive_concat',max_hdr_lines=>10000,max_body_lines=>10000,nfiles=>10); run_test(\&test_vcf_concat,$opts,in=>['concat.4.a','concat.4.b'],out=>'concat.5.out',do_bcf=>0,args=>'-l'); run_test(\&test_vcf_concat,$opts,in=>['concat.4.a','concat.4.b'],out=>'concat.5.out',do_bcf=>1,args=>'-l'); run_test(\&test_vcf_concat,$opts,in=>['concat.5.a','concat.5.b','concat.5.c'],out=>'concat.5.1.out',do_bcf=>0,args=>'-l --ligate-warn'); run_test(\&test_vcf_concat,$opts,in=>['concat.5.a','concat.5.b','concat.5.c'],out=>'concat.5.1.out',do_bcf=>1,args=>'-l --ligate-warn'); run_test(\&test_vcf_concat,$opts,in=>['concat.5.a','concat.5.b','concat.5.c'],out=>'concat.5.2.out',do_bcf=>1,args=>'-l --ligate-force'); run_test(\&test_vcf_concat,$opts,in=>['concat.5.a','concat.5.b','concat.5.c'],out=>'concat.5.3.out',do_bcf=>0,args=>'-G -a -D'); run_test(\&test_vcf_concat,$opts,in=>['concat.5.a','concat.5.b','concat.5.c'],out=>'concat.5.3.out',do_bcf=>1,args=>'-G -a -D'); run_test(\&test_vcf_reheader,$opts,in=>'reheader',out=>'reheader.1.out',header=>'reheader.hdr'); run_test(\&test_vcf_reheader,$opts,in=>'reheader',out=>'reheader.2.out',samples=>'reheader.samples'); run_test(\&test_vcf_reheader,$opts,in=>'reheader',out=>'reheader.2.out',samples=>'reheader.samples2'); run_test(\&test_vcf_reheader,$opts,in=>'reheader',out=>'reheader.3.out',samples=>'reheader.samples3'); run_test(\&test_vcf_reheader,$opts,in=>'reheader',out=>'reheader.4.out',samples=>'reheader.samples4'); run_test(\&test_vcf_reheader,$opts,in=>'empty',out=>'reheader.empty.out',header=>'reheader.empty.hdr'); run_test(\&test_vcf_reheader,$opts,in=>'reheader.2',out=>'reheader.5.out',args=>'-f {PATH}/reheader.fai',nostdin=>1); run_test(\&test_vcf_reheader,$opts,in=>'reheader.2',out=>'reheader.5.out',args=>'-h {PATH}/reheader.2.hdr -f {PATH}/reheader.fai',nostdin=>1); run_test(\&test_vcf_reheader,$opts,in=>'reheader.3',out=>'reheader.6.out',args=>'-f {PATH}/reheader.3.fai',nostdin=>1); run_test(\&test_rename_chrs,$opts,in=>'annotate'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.gs.gt.gen',args=>'-g -,.'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.gs.gt.ids.gen',args=>'-g -,. --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.gs.gt.ids.gen6',args=>'-g -,. --vcf-ids --3N6'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.gs.gt.samples',args=>'-g .,-'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.gs.gt.ids.gen',s=>'convert.gs.gt.samples',out=>'convert.gs.vcf',args=>' --vcf-ids -G'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.gs.gt.ids.gen',s=>'convert.gs.gt.samples',out=>'convert.gs.noids.vcf',args=>'-G'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.gs.gt.ids.3N6.gen',s=>'convert.gs.gt.samples',out=>'convert.gs.noids.vcf',args=>'--3N6 -G'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.gs.gt.ids.gen.rev',s=>'convert.gs.gt.samples',out=>'convert.gs.vcf',args=>'--vcf-ids -G'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.gs.gt.ids.gen.rev',s=>'convert.gs.gt.samples',out=>'convert.gs.noids.vcf',args=>'-G'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.gs.pl.gen',args=>'-g -,. --tag PL'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.gs.pl.samples',args=>'-g .,- --tag PL'); run_test(\&test_vcf_convert,$opts,in=>'check',out=>'check.gs.vcfids.gen',args=>'-g -,. --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'check',out=>'check.gs.vcfids.samples',args=>'-g .,- --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'check',out=>'check.gs.chrom.gen',args=>'-g -,. --3N6'); run_test(\&test_vcf_convert,$opts,in=>'check',out=>'check.gs.chrom.samples',args=>'-g .,- --3N6'); run_test(\&test_vcf_convert,$opts,in=>'check',out=>'check.gs.vcfids_chrom.gen',args=>'-g -,. --3N6 --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'check',out=>'check.gs.vcfids_chrom.samples',args=>'-g .,- --3N6 --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hls.haps',args=>'-h -,.,.'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hls.legend',args=>'-h .,-,.'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hls.ids.legend',args=>'-h .,-,. --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hls.samples',args=>'-h .,.,-'); run_test(\&test_vcf_convert_hls2vcf,$opts,h=>'convert.hls.gt.hap',l=>'convert.hls.gt.legend',s=>'convert.hls.gt.samples',out=>'convert.gt.noHead.vcf',args=>'-H'); run_test(\&test_vcf_convert,$opts,in=>'convert.hap-missing',out=>'convert.hap-missing.haps',args=>'--haplegendsample -,.,.'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hs.hap',args=>'--hapsample -,.'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hs.ids.hap',args=>'--hapsample -,. --vcf-ids'); run_test(\&test_vcf_convert,$opts,in=>'convert',out=>'convert.hs.sample',args=>'--hapsample .,-'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.hs.gt.hap',s=>'convert.hs.gt.samples',out=>'convert.gt.noHead.vcf',args=>'--hapsample2vcf'); run_test(\&test_vcf_convert_hs2vcf,$opts,h=>'convert.hs.gt.ids.hap',s=>'convert.hs.gt.samples',out=>'convert.gt.noHead.ids.vcf',args=>'--vcf-ids --hapsample2vcf'); run_test(\&test_vcf_convert_gvcf,$opts,in=>'convert.gvcf',out=>'convert.gvcf.out',fa=>'gvcf.fa',args=>'--gvcf2vcf -i\'FILTER="PASS"\''); run_test(\&test_vcf_convert_tsv2vcf,$opts,in=>'convert.23andme',out=>'convert.23andme.vcf',args=>'-c ID,CHROM,POS,AA -s SAMPLE1',fai=>'23andme'); run_test(\&test_vcf_convert_tsv2vcf,$opts,in=>'convert.tsv',out=>'convert.tsv.vcf',args=>'-c -,CHROM,POS,REF,ALT',fai=>'23andme'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.overlaps.1',out=>'consensus.overlaps.1.1.out',fa=>'consensus.overlaps.1.fa',args=>'-s A'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.overlaps.1',out=>'consensus.overlaps.1.2.out',fa=>'consensus.overlaps.1.fa',args=>'-s B'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.overlaps.1',out=>'consensus.overlaps.1.3.out',fa=>'consensus.overlaps.1.fa',args=>'-s A -a N'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.overlaps.1',out=>'consensus.overlaps.1.4.out',fa=>'consensus.overlaps.1.fa',args=>'-s B -a N'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.beyond',out=>'consensus.beyond.1.out',fa=>'consensus.beyond.fa',args=>''); run_test(\&test_vcf_consensus,$opts,in=>'consensus',out=>'consensus.1.out',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-s -'); run_test(\&test_vcf_consensus_chain,$opts,in=>'consensus',out=>'consensus.1.chain',chain=>'consensus.1.chain',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus',out=>'consensus.2.out',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-H 1'); run_test(\&test_vcf_consensus_chain,$opts,in=>'consensus',out=>'consensus.2.chain',chain=>'consensus.2.chain',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-H 1'); run_test(\&test_vcf_consensus,$opts,in=>'consensus',out=>'consensus.3.out',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-I -s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus',out=>'consensus.16.out',fa=>'consensus.fa',args=>'-s - -I -m {PATH}/consensus.tab --mask-with X -m {PATH}/consensus.tab --mask-with lc'); run_test(\&test_vcf_consensus_chain,$opts,in=>'consensus',out=>'consensus.3.chain',chain=>'consensus.3.chain',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-I'); run_test(\&test_vcf_consensus,$opts,in=>'consensus',out=>'consensus.4.out',fa=>'consensus.fa',args=>'-H 1'); run_test(\&test_vcf_consensus_chain,$opts,in=>'consensus',out=>'consensus.4.chain',chain=>'consensus.4.chain',fa=>'consensus.fa',args=>'-H 1'); run_test(\&test_vcf_consensus,$opts,in=>'consensus2',out=>'consensus2.1.out',fa=>'consensus2.fa',args=>'-H 1'); run_test(\&test_vcf_consensus,$opts,in=>'consensus2',out=>'consensus2.2.out',fa=>'consensus2.fa',args=>'-H 2'); run_test(\&test_vcf_consensus,$opts,in=>'empty',out=>'consensus.5.out',fa=>'consensus.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus3',out=>'consensus3.out',fa=>'consensus2.fa',args=>'-H 2 -M "?"'); run_test(\&test_vcf_consensus,$opts,in=>'consensus3',out=>'consensus3.2.out',fa=>'consensus2.fa',args=>'-H 2 -M "?" -p xx_'); run_test(\&test_vcf_consensus,$opts,in=>'consensus4',out=>'consensus4.out',fa=>'consensus2.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus5',out=>'consensus5.out',fa=>'consensus5.fa',args=>'--haplotype LA'); run_test(\&test_vcf_consensus,$opts,in=>'consensus6',out=>'consensus6.out',fa=>'consensus6.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7a.out',fa=>'consensus7.fa',args=>'-H 2'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7a.out',fa=>'consensus7.fa',args=>'-H 4'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7b.out',fa=>'consensus7.fa',args=>'-H 2pIu'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7b.out',fa=>'consensus7.fa',args=>'-H 4pIu'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7c.out',fa=>'consensus7.fa',args=>'-H 1'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7c.out',fa=>'consensus7.fa',args=>'-H 3'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7d.out',fa=>'consensus7.fa',args=>'-H 1pIu'); run_test(\&test_vcf_consensus,$opts,in=>'consensus7',out=>'consensus7d.out',fa=>'consensus7.fa',args=>'-H 3pIu'); run_test(\&test_vcf_consensus,$opts,in=>'consensus8',out=>'consensus.8a.out',fa=>'consensus.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus8',out=>'consensus.8b.out',fa=>'consensus.fa',args=>'-s - -a .'); run_test(\&test_vcf_consensus,$opts,in=>'consensus8',out=>'consensus.8c.out',fa=>'consensus.fa',args=>q[-s - -a . -i 'type="snp" || type="ref"']); run_test(\&test_vcf_consensus,$opts,in=>'consensus8',out=>'consensus.8d.out',fa=>'consensus.fa',args=>q[-s - -a . -i 'ALT!=""']); run_test(\&test_vcf_consensus,$opts,in=>'consensus8',out=>'consensus.8e.out',fa=>'consensus.fa',args=>q[-s - -a . -e 'MinDP>15']); run_test(\&test_vcf_consensus,$opts,in=>'consensus8',out=>'consensus.8f.out',fa=>'consensus.fa',args=>q[-s - -a . -e 'MinDP<15']); run_test(\&test_vcf_consensus,$opts,in=>'consensus.9',out=>'consensus.9.1.out',fa=>'consensus.9.1.fa',args=>q[-H A]); run_test(\&test_vcf_consensus,$opts,in=>'consensus.9',out=>'consensus.9.2.out',fa=>'consensus.9.2.fa',args=>q[-H A]); run_test(\&test_vcf_consensus,$opts,in=>'consensus.10',out=>'consensus.9.1.out',fa=>'consensus.9.1.fa',args=>q[-H A]); run_test(\&test_vcf_consensus,$opts,in=>'consensus.10',out=>'consensus.9.2.out',fa=>'consensus.9.2.fa',args=>q[-H A]); run_test(\&test_vcf_consensus,$opts,in=>'consensus.11',out=>'consensus.11.1.out',fa=>'consensus.11.fa',args=>q[-s smpl]); run_test(\&test_vcf_consensus,$opts,in=>'consensus.11',out=>'consensus.11.2.out',fa=>'consensus.11.fa',args=>q[-s smpl -a N]); run_test(\&test_vcf_consensus,$opts,in=>'consensus.12',out=>'consensus.12.out',fa=>'consensus.12.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.13',out=>'consensus.13.out',fa=>'consensus.13.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.14',out=>'consensus.14.out',fa=>'consensus.14.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.12',out=>'consensus.15.out',fa=>'consensus.12.fa',args=>'-s - --mark-del - --mark-ins uc --mark-snv uc'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.12',out=>'consensus.19.out',fa=>'consensus.12.fa',args=>'-s - --mark-del - --mark-ins + --mark-snv :'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.15',out=>'consensus.17.out',fa=>'consensus.15.fa',args=>'-H I --mark-ins lc --mark-snv lc'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.16',out=>'consensus.18.out',fa=>'consensus.fa',args=>'-s - -I'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.16',out=>'consensus.18.out',fa=>'consensus.fa',args=>'-H I'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.17',out=>'consensus17.1.out',fa=>'consensus2.fa',mask=>'consensus.17.bed',args=>'-s - -M N'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.18',out=>'consensus18.1.out',fa=>'consensus.18.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.19',out=>'consensus19.1.out',fa=>'consensus.19.fa',args=>'-s - '); run_test(\&test_vcf_consensus,$opts,in=>'consensus.20',out=>'consensus20.1.out',fa=>'consensus.20.fa',args=>'-s -'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.20',out=>'consensus20.2.out',fa=>'consensus.20.fa',args=>''); run_test(\&test_vcf_consensus,$opts,in=>'consensus.20',out=>'consensus20.3.out',fa=>'consensus.20.fa',args=>'-M . -s b'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.20',out=>'consensus20.4.out',fa=>'consensus.20.fa',args=>'-M . -s a'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.21',out=>'consensus21.1.out',fa=>'consensus.21.fa',args=>''); run_test(\&test_vcf_consensus,$opts,in=>'consensus.22',out=>'consensus22.1.out',fa=>'consensus.22.fa',args=>'--regions-overlap 0 --mark-del .'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.22',out=>'consensus22.2.out',fa=>'consensus.22.fa',args=>'--regions-overlap 1 --mark-del .'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.22',out=>'consensus22.2.out',fa=>'consensus.22.fa',args=>'--regions-overlap 2 --mark-del .'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.22',out=>'consensus22.1.out',fa=>'consensus.22.fa',args=>'--regions-overlap 0'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.22',out=>'consensus22.3.out',fa=>'consensus.22.fa',args=>'--regions-overlap 1'); run_test(\&test_vcf_consensus,$opts,in=>'consensus.22',out=>'consensus22.3.out',fa=>'consensus.22.fa',args=>'--regions-overlap 2'); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.1.out',args=>q[-r17:100-150 -a -AD],test_list=>1); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.2.out',args=>q[-a DP,DV -r17:100-600 -a -AD]); # test files from samtools mpileup test suite run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1)],out=>'mpileup/mpileup.3.out',args=>q[-B --ff 0x14 -r17:1050-1060 -a -AD]); # test file converted to vcf from samtools mpileup test suite run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.4.out',args=>q[-a DP,DPR,DV,DP4,INFO/DPR,SP,-AD -r17:100-600]); #test files from samtools mpileup test suite run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.5.out',args=>q[-a DP,AD,ADF,ADR,SP,INFO/AD,INFO/ADF,INFO/ADR -r17:100-600]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.6.out',args=>q[-a DP,DV,-AD -r17:100-600 --gvcf 0,2,5]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.6.out',args=>q[-a DP,DV,-AD -r17:100-200,17:201-300,17:301-400,17:401-500,17:501-600 --gvcf 0,2,5]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.7.out',args=>q[-a -AD -r17:100-150 -s HG00101,HG00102]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.7.out',args=>q[-a -AD -r17:100-150 -S {PATH}/mplp.samples]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.8.out',args=>q[-a -AD -r17:100-150 -s ^HG00101,HG00102]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.8.out',args=>q[-a -AD -r17:100-150 -S ^{PATH}/mplp.samples]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.9.out',args=>q[-a -AD -t17:100-150 -S {PATH}/mplp.9.samples]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.1 mpileup.2 mpileup.3)],out=>'mpileup/mpileup.10.out',args=>q[-a -AD -t17:100-150 -G {PATH}/mplp.10.samples]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.3)],out=>'mpileup/mpileup.11.out',args=>q[-a -AD]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.3 mpileup.4)],out=>'mpileup/mpileup.11.out',args=>q[-a -AD -s HG00102]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.3 mpileup.4)],out=>'mpileup/mpileup.11.out',args=>q[-a -AD -s ^HG99999]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.3 mpileup.4)],out=>'mpileup/mpileup.11.out',args=>q[-a -AD -G {PATH}/mplp.11.rgs]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup.3 mpileup.4)],out=>'mpileup/mpileup.11.out',args=>q[-a -AD -G {PATH}/mplp.11.rgs]); run_test(\&test_mpileup,$opts,in=>[qw(indel-AD.1)],out=>'mpileup/indel-AD.1.out',ref=>'indel-AD.1.fa',args=>q[-a AD]); run_test(\&test_mpileup,$opts,in=>[qw(indel-AD.1)],out=>'mpileup/indel-AD.1cns.out',ref=>'indel-AD.1.fa',args=>q[-a AD --indels-cns]); run_test(\&test_mpileup,$opts,in=>[qw(indel-AD.2)],out=>'mpileup/indel-AD.2.out',ref=>'indel-AD.2.fa',args=>q[-a AD -r 11:75]); run_test(\&test_mpileup,$opts,in=>[qw(indel-AD.2)],out=>'mpileup/indel-AD.3.out',ref=>'indel-AD.2.fa',args=>q[-a AD -r 11:75 --ambig-reads incAD]); run_test(\&test_mpileup,$opts,in=>[qw(indel-AD.2)],out=>'mpileup/indel-AD.4.out',ref=>'indel-AD.2.fa',args=>q[-a AD -r 11:75 --ambig-reads incAD0]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup-SCR)],out=>'mpileup/mpileup-SCR.out',ref=>'mpileup-SCR.fa',args=>q[-a -AD,INFO/SCR,FMT/SCR]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup-filter)],out=>'mpileup/mpileup-filter.1.out',ref=>'mpileup-SCR.fa',args=>q[-a -AD -t 1:100 --skip-all-set PAIRED,PROPER_PAIR,MREVERSE]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup-filter)],out=>'mpileup/mpileup-filter.1.out',ref=>'mpileup-SCR.fa',args=>q[-a -AD -t 1:100 --skip-any-set READ1]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup-filter)],out=>'mpileup/mpileup-filter.2.out',ref=>'mpileup-SCR.fa',args=>q[-a -AD -t 1:100 --skip-all-unset READ1]); run_test(\&test_mpileup,$opts,in=>[qw(mpileup-filter)],out=>'mpileup/mpileup-filter.2.out',ref=>'mpileup-SCR.fa',args=>q[-a -AD -t 1:100 --skip-any-unset READ1]); run_test(\&test_mpileup,$opts,in=>[qw(annot-NMBZ.1)],ref=>'annot-NMBZ.1.fa',out=>'mpileup/annot-NMBZ.1.1.out',args=>q[-a -AD,INFO/NMBZ -r chr19:69-99]); run_test(\&test_mpileup,$opts,in=>[qw(annot-NMBZ.2)],ref=>'annot-NMBZ.2.fa',out=>'mpileup/annot-NMBZ.2.1.out',args=>q[-a -AD,INFO/NMBZ -r chr6:75]); run_test(\&test_mpileup,$opts,in=>[qw(annot-NMBZ.3.1 annot-NMBZ.3.2)],ref=>'annot-NMBZ.3.fa',out=>'mpileup/annot-NMBZ.3.1.out',args=>q[-a -AD,INFO/NMBZ -r chr16:75]); run_test(\&test_csq,$opts,in=>'csq',out=>'csq.1.out',cmd=>'-f {PATH}/csq.fa -g {PATH}/csq.gff3'); run_test(\&test_csq,$opts,in=>'csq',out=>'csq.1.out',cmd=>'-f {PATH}/csq.fa -g {PATH}/csq.chr.gff3'); run_test(\&test_csq,$opts,in=>'csq.2',out=>'csq.2.out',cmd=>'-f {PATH}/csq.fa -g {PATH}/csq.2.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.2',out=>'csq.3.out',cmd=>'-f {PATH}/csq.fa -g {PATH}/csq.2.gff --ncsq 64',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.nchr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.nchr.fa -g {PATH}/csq.nchr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.nchr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.ychr.fa -g {PATH}/csq.nchr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.nchr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.nchr.fa -g {PATH}/csq.ychr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.nchr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.ychr.fa -g {PATH}/csq.ychr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.ychr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.ychr.fa -g {PATH}/csq.ychr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.ychr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.ychr.fa -g {PATH}/csq.nchr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.ychr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.nchr.fa -g {PATH}/csq.ychr.gff',tbcsq=>1); run_test(\&test_csq,$opts,in=>'csq.ychr',out=>'csq.chr.out',cmd=>'-f {PATH}/csq.nchr.fa -g {PATH}/csq.nchr.gff',tbcsq=>1); run_test(\&test_csq_real,$opts,in=>'csq'); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.1.out',args=>q[-Or -G30 --AF-dflt 0.4]); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.1.out',args=>q[-Or -G30 --AF-file {PATH}/roh.1.tab.gz]); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.1.out',args=>q[-Or -G30 --AF-file {PATH}/roh.1.tab.gz --ignore-homref]); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.2.out',args=>q[ -G30 --AF-dflt 0.4 -r 1:100174876-100318245]); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.3.out',args=>q[ -G30 --AF-dflt 0.4 -r 1:100174876-100318245 --ignore-homref]); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.3.out',args=>q[ -G30 --AF-dflt 0.4 -r 1:100174876-100318245 --ignore-homref --include-noalt]); run_test(\&test_roh,$opts,in=>'roh.1',out=>'roh.1.4.out',args=>q[ -G30 --AF-dflt 0.4 -r 1:100174876-100318245 --include-noalt]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.2.out',args=>q[-e 0 --no-HWE-prob]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.out',args=>q[-e 0]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.out',args=>q[-e 0 -u GT,GT]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.out',args=>q[-e 0 -u GT,PL]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.out',args=>q[-e 0 -u PL,GT]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.out',args=>q[-e 0 -u PL,PL]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.1.out',args=>q[-e 0 -p s1,s1]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.2',gts=>'gtcheck.1.gts',out=>'gtcheck.2.out',args=>q[-e 0]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.3.out',args=>q[-e 0 ]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.3.out',args=>q[-e 0 -p B,A,C,A,C,B,D,A,D,B,D,C,E,A,E,B,E,C,E,D]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.3.out',args=>q[-e 0 -P {PATH}/gtcheck.3.pairs]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.3.out',args=>q[-e 0 -u PL]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.9.out',args=>q[-e 0 --n-matches 4],sort=>1); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.4.out',args=>q[-e 0 -s qry:E,D,C]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.4.out',args=>q[-e 0 -s qry:E,D,C -u PL]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.5.out',args=>q[-e 0 -s qry:B -s gt:D]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.5.out',args=>q[-e 0 -s qry:B -s gt:D -u PL]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.6.out',args=>q[-e 0 -s qry:B -s gt:D,C]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.6.out',args=>q[-e 0 -p B,C,B,D]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.7.out',args=>q[-e 0 -u GT,GT -H]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.7.out',args=>q[-e 0 -u GT,PL -H]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.7.out',args=>q[-e 0 -u PL,GT -H]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.7.out',args=>q[-e 0 -u PL,PL -H]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.4',out=>'gtcheck.8.out',args=>q[-e 0 -P {PATH}/gtcheck.4.pairs --distinctive-sites 3]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.4',out=>'gtcheck.8.out',args=>q[-e 0 -P {PATH}/gtcheck.4.pairs --distinctive-sites 3,1]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.10.out',args=>q[-u GT -e 30]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.10.out',args=>q[-u GT -e 30 -p s1,s1]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.1',gts=>'gtcheck.1.gts',out=>'gtcheck.11.out',args=>q[-u GT -e 300]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.12.out',args=>q[-u PL -e 30]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.ntop',gts=>'gtcheck.ntop.gts',out=>'gtcheck.ntop.1.out',args=>q[]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.ntop',gts=>'gtcheck.ntop.gts',out=>'gtcheck.ntop.2.out',args=>q[--n-matches 2]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.5',gts=>'gtcheck.5.gts',out=>'gtcheck.5.1.out',args=>q[],grep=>'grep -v Time'); run_test(\&test_gtcheck,$opts,in=>'gtcheck.6',out=>'gtcheck.6.1.out',args=>q[-p A,B,B,C]); run_test(\&test_gtcheck,$opts,in=>'gtcheck.3',out=>'gtcheck.3.1.out',args=>q[-t 11:33 -p A,D,A,E,D,E -u GT -e 10]); print "\nNumber of tests:\n"; printf " total .. %d\n", $$opts{nok}+$$opts{nfailed}; printf " passed .. %d\n", $$opts{nok}; printf " failed .. %d\n", $$opts{nfailed}; print "\n"; exit ($$opts{nfailed} != 0); #-------------------- sub error { my (@msg) = @_; if ( scalar @msg ) { confess @msg; } print "About: htslib consistency test script\n", "Usage: test.pl [OPTIONS]\n", "Options:\n", " -f, --function LIST Run only the listed tests (e.g. 'test_mpileup,split-vep')\n", " -p, --plugins Test also plugins, requires libhts.so.\n", " -r, --redo-outputs Recreate expected output files.\n", " -t, --temp-dir When given, temporary files will not be removed.\n", " -h, -?, --help This help message.\n", "\n"; exit -1; } sub cygpath { my ($path) = @_; $path = `cygpath -m $path`; $path =~ s/\r?\n//; return $path } sub safe_tempdir { my $dir = tempdir(CLEANUP=>1); if ($^O =~ /^msys/) { $dir = cygpath($dir); } return $dir; } sub parse_params { my $opts = { bgzip=>"bgzip", keep_files=>0, nok=>0, nfailed=>0, tabix=>"tabix", plugins=>0, htsdir=>"" }; my $help; Getopt::Long::Configure('bundling'); my $ret = GetOptions ( 'e|exec=s' => sub { my ($tool, $path) = split /=/, $_[1]; $$opts{$tool} = $path if $path }, 't|temp-dir:s' => \$$opts{keep_files}, 'p|plugins' => \$$opts{test_plugins}, 'r|redo-outputs' => \$$opts{redo_outputs}, 'h|?|help' => \$help, 'i|htsdir:s' => \$$opts{htsdir}, 'f|function:s' => \$$opts{function} ); if ( !$ret or $help ) { error(); } if ( $$opts{htsdir} ) { if ($^O eq 'cygwin' || $^O =~ /^msys/) { # Set PATH so against-htslib-source builds can find the htslib dll $ENV{PATH} = "$$opts{htsdir}:"."$$opts{htsdir}/bin:"."$$opts{htsdir}/lib:".$ENV{PATH}; } } $$opts{tmp} = $$opts{keep_files} ? $$opts{keep_files} : safe_tempdir; if ( $$opts{keep_files} ) { cmd("mkdir -p $$opts{keep_files}"); } $$opts{path} = $FindBin::RealBin; $$opts{bin} = $FindBin::RealBin; $$opts{bin} =~ s{/test/?$}{}; if ($^O =~ /^msys/) { $$opts{path} = cygpath($$opts{path}); $$opts{bin} = cygpath($$opts{bin}); } return $opts; } sub run_test { my ($func,$opts,@args) = @_; if ( $$opts{function} ) { if ( !exists($$opts{run_function}) ) { $$opts{run_function} = { map {$_=>1} split(/,/,$$opts{function}) }; use B qw(svref_2object); } my $name = svref_2object($func)->GV->NAME; my %args = @args; my $run = 0; if ( exists($$opts{run_function}{$name}) ) { $run = 1; } if ( !$run ) { for my $func (keys %{$$opts{run_function}}) { if ( exists($args{cmd}) && $args{cmd}=~/$func/ ) { $run = 1; last; } if ( $name=~/$func/ ) { $run = 1; last; } } } if ( !$run ) { return; } } &$func($opts,@args); } sub _cmd { my ($cmd) = @_; my $kid_io; my @out; my $pid = open($kid_io, "-|"); if ( !defined $pid ) { error("Cannot fork: $!"); } if ($pid) { # parent @out = <$kid_io>; close($kid_io); } else { # child exec('bash', '-o','pipefail','-c', $cmd) or error("Cannot execute the command [bash -o pipefail -c $cmd]: $!"); } return ($? >> 8, join('',@out)); } sub _cmd3 { my ($cmd) = @_; my $tmp = "$$opts{tmp}/tmp"; my $pid = fork(); if ( !$pid ) { exec('bash', '-o','pipefail','-c', "($cmd) 2>$tmp.e >$tmp.o"); } waitpid($pid,0); my $status = $? >> 8; my $signal = $? & 127; my (@out,@err); if ( open(my $fh,'<',"$tmp.o") ) { @out = <$fh>; close($fh) or error("Failed to close $tmp.o"); } if ( open(my $fh,'<',"$tmp.e") ) { @err = <$fh>; close($fh) or error("Failed to close $tmp.e"); } unlink("$tmp.o"); unlink("$tmp.e"); return ($status,join('',@out),join('',@err)); } sub cmd { my ($cmd) = @_; my ($ret,$out) = _cmd($cmd); if ( $ret ) { error("The command failed: $cmd\n", $out); } return $out; } sub test_cmd { my ($opts,%args) = @_; if ( !exists($args{out}) ) { if ( !exists($args{in}) ) { error("FIXME: expected out or in key\n"); } $args{out} = "$args{in}.out"; } my ($package, $filename, $line, $test)=caller(1); $test =~ s/^.+:://; print "$test:\n"; print "\t$args{cmd}\n"; my ($ret,$out,$err) = _cmd3("$args{cmd}"); if ( length($err) ) { $err =~ s/\n/\n\t\t/gs; $err = "\n\n\t\t$err\n"; } if ( $ret && !$args{expected_failure} ) { failed($opts,$test,"Non-zero status $ret$err"); return; } if ( $args{expected_failure} ) { if ( !$ret ) { failed($opts,$test,"Expected failure but the test returned $ret$err"); } else { passed($opts,$test,"ok, expected non-zero status"); } return; } if ( $$opts{redo_outputs} && -e "$$opts{path}/$args{out}" ) { rename("$$opts{path}/$args{out}","$$opts{path}/$args{out}.old"); open(my $fh,'>',"$$opts{path}/$args{out}") or error("$$opts{path}/$args{out}: $!"); print $fh $out; close($fh); my ($ret,$out) = _cmd("diff -q $$opts{path}/$args{out} $$opts{path}/$args{out}.old"); if ( !$ret && $out eq '' ) { unlink("$$opts{path}/$args{out}.old"); } else { print "\tthe expected output changed, saving:\n"; print "\t old .. $$opts{path}/$args{out}.old\n"; print "\t new .. $$opts{path}/$args{out}\n"; } } my $exp = ''; if ( exists($args{exp}) ) { $exp = $args{exp}; } elsif ( open(my $fh,'<',"$$opts{path}/$args{out}") ) { my @exp = <$fh>; $exp = join('',@exp); close($fh); } else { open(my $fh,'>',"$$opts{path}/$args{out}.new") or error("$$opts{path}/$args{out}.new: $!"); print $fh $out; close($fh); if ( !$$opts{redo_outputs} ) { failed($opts,$test,"$$opts{path}/$args{out}.new"); return; } } $exp =~ s/\r\n/\n/g; # if ($args{text}); ## simplified as all tests are text? $out =~ s/\r\n/\n/g; # if ($args{text}); ## simplified as all tests are text? $out =~ s/e([-+])0(\d\d)/e$1$2/g if ($args{exp_fix}); if ( $exp ne $out ) { open(my $fh,'>',"$$opts{path}/$args{out}.new") or error("$$opts{path}/$args{out}.new"); print $fh $out; close($fh); if ( !-e "$$opts{path}/$args{out}" && !exists($args{exp}) ) { rename("$$opts{path}/$args{out}.new","$$opts{path}/$args{out}") or error("rename $$opts{path}/$args{out}.new $$opts{path}/$args{out}: $!"); print "\tthe file with expected output does not exist, creating new one:\n"; print "\t\t$$opts{path}/$args{out}\n"; } else { if ( exists($args{exp}) ) { open(my $fh,'>',"$$opts{path}/$args{out}") or error("$$opts{path}/$args{out}"); print $fh $exp; close($fh); } my @diff = `diff $$opts{path}/$args{out} $$opts{path}/$args{out}.new`; for (my $i=0; $i<@diff; $i++) { $diff[$i] = "\t\t\t".$diff[$i]; } chomp($diff[-1]); failed($opts,$test,"The outputs differ:\n\t\t$$opts{path}/$args{out}\n\t\t$$opts{path}/$args{out}.new$err\n".join('',@diff)); } return; } passed($opts,$test); } sub failed { my ($opts,$test,$reason) = @_; $$opts{nfailed}++; if ( defined $reason ) { print "\n\t$reason"; } print "\n.. failed ...\n\n"; } sub passed { my ($opts,$test,$reason) = @_; $$opts{nok}++; if ( !defined $reason ) { $reason = 'ok'; } print ".. $reason\n\n"; } sub is_file_newer { my ($afile,$bfile) = @_; my (@astat) = stat($afile) or return 0; my (@bstat) = stat($bfile) or return 0; if ( $astat[9]>$bstat[9] ) { return 1 } return 0; } sub bgzip_tabix { my ($opts,%args) = @_; my $file = "$args{file}.$args{suffix}"; if ( $file=~m{/[^/]+} ) { cmd("mkdir -p $$opts{tmp}/$`"); } # create a subdirectory if necessary if ( $$opts{redo_outputs} or !-e "$$opts{tmp}/$file.gz" or is_file_newer("$$opts{path}/$file","$$opts{tmp}/$file.gz") ) { cmd("cat $$opts{path}/$file | $$opts{bgzip} -c > $$opts{tmp}/$file.gz"); } if ( $$opts{redo_outputs} or !-e "$$opts{tmp}/$file.gz.tbi" or is_file_newer("$$opts{tmp}/$file.gz","$$opts{tmp}/$file.gz.tbi") ) { cmd("$$opts{tabix} -f $args{args} $$opts{tmp}/$file.gz"); } } sub bgzip_tabix_vcf { my ($opts,$file) = @_; bgzip_tabix($opts,file=>$file,suffix=>'vcf',args=>'-p vcf'); } sub bgzip_index_bcf { my ($opts,$file) = @_; if ( !-e "$$opts{tmp}/$file.bcf" or is_file_newer("$$opts{path}/$file.vcf","$$opts{tmp}/$file.bcf") ) { cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$file.vcf -o $$opts{tmp}/$file.bcf"); } if ( !-e "$$opts{tmp}/$file.bcf.csi" or is_file_newer("$$opts{tmp}/$file.bcf","$$opts{tmp}/$file.bcf.csi") ) { cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$file.bcf"); } } # The tests -------------------------- sub test_tabix { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); test_cmd($opts,%args,cmd=>"$$opts{tabix} $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); cmd("$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.bcf"); cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); } sub test_index { my ($opts,%args) = @_; cmd("$$opts{bin}/bcftools view -Oz $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.vcf.gz"); cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.vcf.gz"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); # output path unlink("$$opts{tmp}/$args{in}.bcf.csi", "$$opts{tmp}/$args{in}.bcf.csi", "$$opts{tmp}/$args{in}.vcf.gz.tbi"); cmd("$$opts{bin}/bcftools index -fo $$opts{tmp}/$args{in}.csi $$opts{tmp}/$args{in}.bcf"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); # streaming cmd("$$opts{bin}/bcftools view -Oz $$opts{path}/$args{in}.vcf | tee $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools index -fo $$opts{tmp}/$args{in}.vcf.gz.csi"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf | tee $$opts{tmp}/$args{in}.bcf | $$opts{bin}/bcftools index -fo $$opts{tmp}/$args{in}.bcf.csi"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); } sub test_vcf_idxstats { my ($opts,%args) = @_; cmd("$$opts{bin}/bcftools view -Oz $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.vcf.gz"); cmd("$$opts{bin}/bcftools index --tbi -f $$opts{tmp}/$args{in}.vcf.gz"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.vcf.gz"); unlink("$$opts{tmp}/$args{in}.vcf.gz.tbi"); cmd("$$opts{bin}/bcftools index --csi -f $$opts{tmp}/$args{in}.vcf.gz"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.vcf.gz"); if ( $args{args} eq '-n' ) { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.vcf.gz.csi"); } unlink("$$opts{tmp}/$args{in}.vcf.gz.csi"); cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.bcf"); if ( $args{args} eq '-n' ) { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.bcf.csi"); } } sub test_vcf_check { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools stats -s - $$opts{tmp}/$args{in}.vcf.gz | grep -v '^# The command' | grep -v '^# This' | grep -v '^ID\t'"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools stats -s - | grep -v '^# The command' | grep -v '^# This' | grep -v '^ID\t'"); } sub test_vcf_check_merge { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); cmd("$$opts{bin}/bcftools stats -r 1 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.1.chk"); cmd("$$opts{bin}/bcftools stats -r 2 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.2.chk"); cmd("$$opts{bin}/bcftools stats -r 3 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.3.chk"); cmd("$$opts{bin}/bcftools stats -r 4 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.4.chk"); test_cmd($opts,%args,cmd=>"$$opts{bin}/misc/plot-vcfstats -m $$opts{tmp}/$args{in}.1.chk $$opts{tmp}/$args{in}.2.chk $$opts{tmp}/$args{in}.3.chk $$opts{tmp}/$args{in}.4.chk | grep -v 'plot-vcfstats' | grep -v '^# The command' | grep -v '^# This' | grep -v '^ID\t'"); } sub test_vcf_stats { my ($opts,%args) = @_; my $files = ''; for my $file (@{$args{in}}) { bgzip_tabix_vcf($opts,$file); $files .= " $$opts{tmp}/$file.vcf.gz"; } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools stats $args{args} $files | grep -v '^#' | grep -v '^ID\t'"); } sub test_vcf_merge { my ($opts,%args) = @_; my @types = exists($args{types}) ? @{$args{types}} : (qw(vcf bcf)); for my $type (@types) { my @files; if ( $args{noidx} ) { for my $file (@{$args{in}}) { if ( $type eq 'vcf' ) { push @files, "$$opts{path}/$file.vcf"; } else { cmd("$$opts{bin}/bcftools view --no-version -Ob -o $$opts{tmp}/$file.bcf $$opts{path}/$file.vcf"); push @files, "$$opts{tmp}/$file.bcf"; } } } else { for my $file (@{$args{in}}) { if ( $type eq 'vcf' ) { bgzip_tabix_vcf($opts,$file); push @files, "$$opts{tmp}/$file.vcf.gz"; } else { cmd("$$opts{bin}/bcftools view --no-version -Ob -o $$opts{tmp}/$file.bcf $$opts{path}/$file.vcf && $$opts{bin}/bcftools index -f $$opts{tmp}/$file.bcf"); push @files, "$$opts{tmp}/$file.bcf"; } } } my $args = exists($args{args}) ? $args{args} : ''; $args =~ s/{PATH}/$$opts{path}/g; my $files = join(' ',@files); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools merge --no-version $args $files", exp_fix=>1); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools merge --no-version -Ob $args $files | $$opts{bin}/bcftools view --no-version | grep -v ^##bcftools_", exp_fix => 1); } } sub test_vcf_isec { my ($opts,%args) = @_; my @files; for my $file (@{$args{in}}) { bgzip_tabix_vcf($opts,$file); push @files, "$$opts{tmp}/$file.vcf.gz"; } my $files = join(' ',@files); $args{args} =~ s/{PATH}/$$opts{path}/g; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec $args{args} $files"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec -Ob $args{args} $files"); } sub test_vcf_isec2 { my ($opts,%args) = @_; my @files; for my $file (@{$args{vcf_in}}) { bgzip_tabix_vcf($opts,$file); push @files, "$$opts{tmp}/$file.vcf.gz"; } my $files = join(' ',@files); $args{args} =~ s/{PATH}/$$opts{path}/g; bgzip_tabix($opts,file=>$args{tab_in},suffix=>'tab',args=>'-s 1 -b 2 -e 3'); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec --no-version $args{args} -T $$opts{tmp}/$args{tab_in}.tab.gz $files"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec -Ob $args{args} -T $$opts{tmp}/$args{tab_in}.tab.gz $files | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); } sub test_vcf_query { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); $args{args} =~ s/{PATH}/$$opts{path}/g; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools query $args{args} $$opts{tmp}/$args{in}.vcf.gz", exp_fix=>1); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query $args{args}", exp_fix=>1); } sub test_vcf_convert { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $$opts{tmp}/$args{in}.vcf.gz"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools convert $args{args}"); } sub test_vcf_convert_hls2vcf { my ($opts,%args) = @_; my $hls = join(',', map { "$$opts{path}/$_" }( $args{h}, $args{l}, $args{s} ) ); if($^O =~ /^msys/) { $hls =~ s/\//\\\\/g; } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hls | grep -v ^##"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hls -Ou | $$opts{bin}/bcftools view | grep -v ^##"); } sub test_vcf_convert_hs2vcf { my ($opts,%args) = @_; my $hs = join(',', map { "$$opts{path}/$_" }( $args{h}, $args{s} ) ); if($^O =~ /^msys/) { $hs =~ s/\//\\\\/g; } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hs | grep -v ^##"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hs -Ou | $$opts{bin}/bcftools view | grep -v ^##"); } sub test_vcf_convert_gvcf { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert --no-version $args{args} -f $$opts{path}/$args{fa} $$opts{tmp}/$args{in}.vcf.gz"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools convert $args{args} -f $$opts{path}/$args{fa} | grep -v ^##bcftools"); } sub test_vcf_convert_tsv2vcf { my ($opts,%args) = @_; my $params = ''; if ( exists($args{args}) ) { $params .= " $args{args}"; } if ( exists($args{fai} ) ) { $params .= " -f $$opts{path}/$args{fai}.fa"; } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert --no-version $params --tsv2vcf $$opts{path}/$args{in}"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert -Ou $params --tsv2vcf $$opts{path}/$args{in} | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); } sub test_vcf_norm { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); my $cmd; if ( !exists($args{args}) ) { $cmd = "$$opts{bin}/bcftools norm --no-version $$opts{tmp}/$args{in}.vcf.gz"; if ( exists($args{fai}) ) { $cmd .= " -f $$opts{path}/$args{fai}.fa"; } } elsif ( ref($args{args}) eq 'ARRAY' ) { my @cmd = (); for my $args (@{$args{args}}) { $args =~ s/{PATH}/$$opts{path}/g; push @cmd, "$$opts{bin}/bcftools norm --no-version $args"; } if ( exists($args{fai}) ) { $cmd[0] .= " -f $$opts{path}/$args{fai}.fa"; } $cmd[0] .= " $$opts{tmp}/$args{in}.vcf.gz"; $cmd = join(' | ',@cmd); } else { $args{args} =~ s/{PATH}/$$opts{path}/g; $cmd = "$$opts{bin}/bcftools norm --no-version $args{args} $$opts{tmp}/$args{in}.vcf.gz"; if ( exists($args{fai}) ) { $cmd .= " -f $$opts{path}/$args{fai}.fa"; } } test_cmd($opts,%args,cmd=>$cmd,exp_fix=>1); test_cmd($opts,%args,cmd=>"$cmd -Ou | $$opts{bin}/bcftools view | grep -v ^##bcftools_",exp_fix=>1); } sub test_vcf_view { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); if ( !exists($args{args}) ) { $args{args} = ''; } if ( !exists($args{reg}) ) { $args{reg} = ''; } if ( exists($args{tgts}) ) { $args{args} .= "-T $$opts{path}/$args{tgts}"; } $args{args} =~ s/{PATH}/$$opts{path}/g; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view --no-version $args{args} $$opts{tmp}/$args{in}.vcf.gz $args{reg}", exp_fix=>1); unless ($args{args} =~ /-H/) { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $args{args} $$opts{tmp}/$args{in}.vcf.gz $args{reg} | $$opts{bin}/bcftools view | grep -v ^##bcftools_", exp_fix=>1); } } sub test_vcf_64bit { my ($opts,%args) = @_; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view $$opts{path}/$args{in}.vcf -H", exp_fix=>1); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools view -H", exp_fix=>1); if ( $args{do_bcf} ) { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view $$opts{path}/$args{in}.vcf -Ou | $$opts{bin}/bcftools view -H", exp_fix=>1); } } sub gen_head_output { my ($h, $n, $desc, $infile) = @_; my $expected = ""; open my $in, '<', $infile or die "Couldn't open $infile: $!\n"; while (<$in>) { my $counter = /^#/? \$h : \$n; next unless $$counter > 0; $expected .= $_; $$counter--; } close $in; return (out => "head.$desc.out", exp => $expected); } sub test_vcf_head { my ($opts, %args) = @_; my $infile = "$$opts{path}/$args{in}"; test_cmd($opts, %args, gen_head_output(1000, 0, "all", $infile), cmd => "$$opts{bin}/bcftools head $infile"); test_cmd($opts, %args, gen_head_output(0, 0, "none", $infile), cmd => "$$opts{bin}/bcftools head -h 0 $infile"); test_cmd($opts, %args, gen_head_output(1, 0, "one", $infile), cmd => "$$opts{bin}/bcftools head -h 1 $infile"); test_cmd($opts, %args, gen_head_output(5, 0, "five", $infile), cmd => "$$opts{bin}/bcftools head -h 5 $infile"); my $nh = $args{in_nheaders}; # Test exactly the number of headers test_cmd($opts, %args, gen_head_output($nh, 0, "exact", $infile), cmd => "$$opts{bin}/bcftools head -h $nh $infile"); $nh++; # Also test asking for one more line than there are headers test_cmd($opts, %args, gen_head_output($nh, 0, "toomany", $infile), cmd => "$$opts{bin}/bcftools head -h $nh $infile"); test_cmd($opts, %args, gen_head_output(1000, 0, "alln0", $infile), cmd => "$$opts{bin}/bcftools head -n 0 $infile"); test_cmd($opts, %args, gen_head_output(1000, 1, "onerec", $infile), cmd => "$$opts{bin}/bcftools head -n 1 $infile"); test_cmd($opts, %args, gen_head_output(1000, 5, "fiverecs", $infile), cmd => "$$opts{bin}/bcftools head -n 5 $infile"); test_cmd($opts, %args, gen_head_output(5, 5, "fiveboth", $infile), cmd => "$$opts{bin}/bcftools head -h 5 -n 5 < $infile"); } sub test_vcf_head2 { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools head $args{args} $$opts{tmp}/$args{in}.vcf.gz"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view --no-version -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools head $args{args}"); } sub test_vcf_call { my ($opts,%args) = @_; $args{args} =~ s/{PATH}/$$opts{path}/g; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call --no-version $args{args} $$opts{path}/$args{in}.vcf"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call -Ob $args{args} $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); } sub test_vcf_call_cAls { my ($opts,%args) = @_; my $args = exists($args{args}) ? $args{args} : ''; bgzip_tabix($opts,file=>$args{tab},suffix=>'tab',args=>'-s1 -b2 -e2'); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call --no-version -mA -C alleles -T $$opts{tmp}/$args{tab}.tab.gz $args $$opts{path}/$args{in}.vcf"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call -Ob -mA -C alleles -T $$opts{tmp}/$args{tab}.tab.gz $args $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); } sub test_vcf_filter { my ($opts,%args) = @_; my $pipe = 'grep -v ^##bcftools_'; if ( exists($args{fmt}) ) { $pipe = "$$opts{bin}/bcftools query -f '$args{fmt}'"; } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools filter $args{args} $$opts{path}/$args{in}.vcf | $pipe", exp_fix=>1); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools filter -Ob $args{args} $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools view | $pipe", exp_fix=>1); } sub test_vcf_sort { my ($opts,%args) = @_; my $pipe = "$$opts{bin}/bcftools query -f '$args{fmt}'"; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools sort $args{args} $$opts{path}/$args{in}.vcf | $pipe"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools sort -Ob $args{args} $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools view | $pipe"); } sub test_vcf_regions { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); # regions vs targets, holding tab in memory my $query = q[%CHROM %POS %REF,%ALT\n]; test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{path}/$args{in}.tab $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{path}/$args{in}.tab],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{path}/$args{in}.tab $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); # regions vs targets, reading tabix-ed tab cmd(qq[cat $$opts{path}/$args{in}.tab | $$opts{bgzip} -c > $$opts{tmp}/$args{in}.tab.gz]); cmd(qq[$$opts{tabix} -f -s1 -b2 -e3 $$opts{tmp}/$args{in}.tab.gz]); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.tab.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.tab.gz],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{tmp}/$args{in}.tab.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); # regions vs targets, holding bed in memory cmd(qq[cat $$opts{path}/$args{in}.tab | awk '{OFS="\\t"}{print \$1,\$2-1,\$3}' > $$opts{tmp}/$args{in}.bed]); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{tmp}/$args{in}.bed $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); # regions vs targets, reading tabix-ed bed cmd(qq[cat $$opts{tmp}/$args{in}.bed | $$opts{bgzip} -c > $$opts{tmp}/$args{in}.bed.gz]); cmd(qq[$$opts{tabix} -f -p bed $$opts{tmp}/$args{in}.bed.gz]); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed.gz],out=>'regions.out'); test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{tmp}/$args{in}.bed.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); } sub test_usage { my ($opts,%args) = @_; my $test = "test_usage"; print "$test:\n"; print "\t$args{cmd}\n"; my $tty_input; if (-t) { $args{redirection} = ""; # no redirection necessary } elsif (eval { require IO::Pty }) { $tty_input = new IO::Pty; # ensure stdin is a terminal, so that subcommands display their usage $args{redirection} = "<'" . $tty_input->ttyname . "'"; } else { warn "$0: module IO::Pty not found; skipping usage tests\n"; return; } my $command = $args{cmd}; my $commandpath = $$opts{bin}."/".$command; my ($ret,$out) = _cmd("$commandpath $args{redirection} 2>&1"); if ( $out =~ m/\/bin\/bash.*no.*such/i ) { failed($opts,$test,"could not run $commandpath: $out"); return; } my @sections = ($out =~ m/(^[A-Za-z]+.*?)(?:(?=^[A-Za-z]+:)|\z)/msg); my $have_usage = 0; my $have_version = 0; my $have_subcommands = 0; my $usage = ""; my @subcommands = (); foreach my $section (@sections) { if ( $section =~ m/^usage/i ) { $have_usage = 1; $section =~ s/^[[:word:]]+[[:punct:]]?[[:space:]]*//; $usage = $section; } elsif ( $section =~ m/^version/i ) { $have_version = 1; } elsif ( $section =~ m/^command/i ) { $have_subcommands = 1; foreach my $line (split /\n/, $section) { push @subcommands, $1 if $line =~ /^\s{2,}(\w+)\s{2,}/; } } } if ( !$have_usage ) { failed($opts,$test,"did not have Usage:"); return; } if ( !$have_version ) { failed($opts,$test,"did not have Version:"); return; } if ( !$have_subcommands ) { failed($opts,$test,"did not have Commands:"); return; } if ( !($usage =~ m/$command/) ) { failed($opts,$test,"usage did not mention $command"); return; } if ( scalar(@subcommands) < 1 ) { failed($opts,$test,"could not parse subcommands"); return; } passed($opts,$test); # now test subcommand usage as well # Under msys the isatty function fails to recognise the terminal. # Skip these tests for now. return if ($^O =~ /^msys/); foreach my $subcommand (@subcommands) { test_usage_subcommand($opts,%args,subcmd=>$subcommand); } } sub test_usage_subcommand { my ($opts,%args) = @_; my $test = "test_usage_subcommand"; print "$test:\n"; print "\t$args{cmd} $args{subcmd}\n"; my $command = $args{cmd}; my $subcommand = $args{subcmd}; my $commandpath = $$opts{bin}."/".$command; my ($ret,$out) = _cmd("$commandpath $subcommand $args{redirection} 2>&1"); if ( $out =~ m/\/bin\/bash.*no.*such/i ) { failed($opts,$test,"could not run $commandpath $subcommand: $out"); return; } my @sections = ($out =~ m/(^[A-Za-z]+.*?)(?:(?=^[A-Za-z]+:)|\z)/msg); my $have_usage = 0; my $usage = ""; foreach my $section (@sections) { if ( $section =~ m/^usage/i ) { $have_usage = 1; $section =~ s/^[[:word:]]+[[:punct:]]?[[:space:]]*//; $usage = $section; } } if ( !$have_usage ) { failed($opts,$test,"did not have Usage:"); return; } if ( !($usage =~ m/$command[[:space:]]+$subcommand/) ) { failed($opts,$test,"usage did not mention $command $subcommand"); return; } passed($opts,$test); } sub test_vcf_annotate { my ($opts,%args) = @_; my ($annot_fname,$in_fname,$hdr); $args{args} =~ s/{PATH}/$$opts{path}/g; if ( exists($args{tab}) ) { bgzip_tabix($opts,file=>$args{tab},suffix=>'tab',args=>'-s1 -b2 -e2'); $annot_fname = "-a $$opts{tmp}/$args{tab}.tab.gz"; $in_fname = "$$opts{path}/$args{in}.vcf"; $hdr = (-e "$$opts{path}/$args{in}.hdr" && !($args{args}=~/-H/) && !($args{args}=~/--header-line\s/)) ? "-h $$opts{path}/$args{in}.hdr" : ''; } elsif ( exists($args{bed}) ) { bgzip_tabix($opts,file=>$args{bed},suffix=>'bed',args=>'-p bed'); $annot_fname = "-a $$opts{tmp}/$args{bed}.bed.gz"; $in_fname = "$$opts{path}/$args{in}.vcf"; $hdr = (-e "$$opts{path}/$args{in}.hdr" && !($args{args}=~/-H/) && !($args{args}=~/--header-line\s/)) ? "-h $$opts{path}/$args{in}.hdr" : ''; } elsif ( exists($args{vcf}) ) { bgzip_tabix_vcf($opts,"$args{in}"); bgzip_tabix_vcf($opts,$args{vcf}); $annot_fname = "-a $$opts{tmp}/$args{vcf}.vcf.gz"; $in_fname = "$$opts{tmp}/$args{in}.vcf.gz"; $hdr = ''; } else { $in_fname = "$$opts{path}/$args{in}.vcf"; $annot_fname = ''; $hdr = ''; } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools annotate $annot_fname $hdr $args{args} $in_fname | $$opts{bin}/bcftools view | grep -v ^##bcftools_", exp_fix=>1); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools annotate -Ob $annot_fname $hdr $args{args} $in_fname | $$opts{bin}/bcftools view | grep -v ^##bcftools_", exp_fix=>1); } sub test_vcf_plugin { my ($opts,%args) = @_; if ( !$$opts{test_plugins} ) { return; } # Sadly, this does not work: # $ENV{BCFTOOLS_PLUGINS} = "$$opts{bin}/plugins"; if ( !exists($args{args}) ) { $args{args} = ''; } my $wpath = $$opts{path}; if ($^O =~ /^msys/) { $wpath = `cygpath -w $$opts{path}`; $wpath =~ s/\r?\n//; } $args{args} =~ s/{QPATH}/$wpath/g; $args{args} =~ s/{PATH}/$$opts{path}/g; $args{cmd} =~ s/{PATH}/$$opts{path}/g; $args{args} =~ s/{TMP}/$$opts{tmp}/g; $args{cmd} =~ s/{TMP}/$$opts{tmp}/g; bgzip_tabix_vcf($opts,"$args{in}"); if ( exists($args{index}) ) { for my $file (@{$args{index}}) { bgzip_tabix_vcf($opts,$file); } } test_cmd($opts,%args,cmd=>"export BCFTOOLS_PLUGINS=$$opts{bin}/plugins; $$opts{bin}/bcftools $args{cmd} $$opts{tmp}/$args{in}.vcf.gz $args{args} | grep -v ^##bcftools_"); cmd("$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.bcf"); cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); test_cmd($opts,%args,cmd=>"export BCFTOOLS_PLUGINS=$$opts{bin}/plugins; $$opts{bin}/bcftools $args{cmd} $$opts{tmp}/$args{in}.bcf $args{args} | grep -v ^##bcftools_", exp_fix=>1); } sub test_vcf_concat { my ($opts,%args) = @_; my $files; for my $file (@{$args{in}}) { if ( $args{do_bcf} ) { cmd("$$opts{bin}/bcftools view --no-version -Ob $$opts{tmp}/$file.vcf.gz > $$opts{tmp}/$file.bcf"); cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$file.bcf"); $files .= " $$opts{tmp}/$file.bcf"; } else { bgzip_tabix_vcf($opts,$file); $files .= " $$opts{tmp}/$file.vcf.gz"; } } test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools concat --no-version $args{args} $files"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools concat -Ob $args{args} $files | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); } sub test_vcf_reheader { my ($opts,%args) = @_; cmd("$$opts{bin}/bcftools view --no-version -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); cmd("$$opts{bin}/bcftools view --no-version -Oz $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.vcf.gz"); my $arg; if ( exists($args{args}) ) { $arg = $args{args}; $arg =~ s/{PATH}/$$opts{path}/g; } elsif ( exists($args{header}) ) { $arg = "-h $$opts{path}/$args{header}"; } else { $arg = "-s $$opts{path}/$args{samples}"; } for my $file ("$$opts{path}/$args{in}.vcf","$$opts{tmp}/$args{in}.bcf","$$opts{tmp}/$args{in}.vcf.gz") { # bcf header lines can come in different order my %bcf_args = (); if ( $file=~/\.bcf$/ && -e "$$opts{path}/$args{out}.bcf" ) { %bcf_args = ( out=>"$args{out}.bcf" ); } test_cmd($opts,%args,%bcf_args,cmd=>"$$opts{bin}/bcftools reheader $arg $file | $$opts{bin}/bcftools view --no-version"); test_cmd($opts,%args,%bcf_args,cmd=>"cat $file | $$opts{bin}/bcftools reheader $arg | $$opts{bin}/bcftools view --no-version") unless $args{nostdin}; } } sub test_rename_chrs { my ($opts,%args) = @_; cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); cmd("$$opts{bin}/bcftools query -f'chr%CHROM\\t%POS\\n' $$opts{path}/$args{in}.vcf > $$opts{path}/rename.out.tmp"); cmd("$$opts{bin}/bcftools query -f'%CHROM\\tchr%CHROM\\n' $$opts{path}/$args{in}.vcf | uniq > $$opts{tmp}/rename.map"); my $prevfailed = $$opts{nfailed}; for my $file ("$$opts{tmp}/$args{in}.bcf","$$opts{path}/$args{in}.vcf") { test_cmd($opts,%args,out=>"rename.out.tmp",cmd=>"$$opts{bin}/bcftools annotate --rename-chrs $$opts{tmp}/rename.map -Ov $file | $$opts{bin}/bcftools query -f'%CHROM\\t%POS\\n'"); test_cmd($opts,%args,out=>"rename.out.tmp",cmd=>"$$opts{bin}/bcftools annotate --rename-chrs $$opts{tmp}/rename.map -Ob $file | $$opts{bin}/bcftools query -f'%CHROM\\t%POS\\n'"); } unlink "$$opts{path}/rename.out.tmp" if $$opts{nfailed} == $prevfailed; } sub test_vcf_consensus { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); bgzip_index_bcf($opts,$args{in}); $args{args} =~ s/{PATH}/$$opts{path}/g; my $mask = $args{mask} ? "-m $$opts{path}/$args{mask}" : ''; my $chain = $args{chain} ? "-c $$opts{tmp}/$args{chain}" : ''; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools consensus $$opts{tmp}/$args{in}.vcf.gz -f $$opts{path}/$args{fa} $args{args} $mask $chain"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools consensus $$opts{tmp}/$args{in}.bcf -f $$opts{path}/$args{fa} $args{args} $mask $chain"); } sub test_vcf_consensus_chain { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); my $mask = $args{mask} ? "-m $$opts{path}/$args{mask}" : ''; my $chain = $args{chain} ? "-c $$opts{tmp}/$args{chain}.new" : ''; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools consensus $$opts{tmp}/$args{in}.vcf.gz -f $$opts{path}/$args{fa} $args{args} $mask $chain >/dev/null; cat $$opts{tmp}/$args{chain}.new"); } sub test_naive_concat { my ($opts,%args) = @_; my $seed = srand(); print STDERR "Random seed for test_naive_concat: $seed\n"; my @hdr = (); my $nhdr = 1 + int(rand($args{max_hdr_lines})); for (my $i=0; $i<$nhdr; $i++) { my $x = rand; push @hdr, "##INFO=\n"; } my @files = (); my $exp = ''; for (my $n=0; $n<$args{nfiles}; $n++) { my $nbdy = int(rand($args{max_body_lines})); my $file = "$$opts{tmp}/$args{name}.$n"; push @files,$file; open(my $fh,'>',"$file.vcf") or error("$file.vcf: $!"); print $fh "##fileformat=VCFv4.0\n"; print $fh "##INFO=\n"; print $fh "##contig=\n"; print $fh join('',@hdr); print $fh join("\t",'#CHROM','POS','ID','REF','ALT','QUAL','FILTER','INFO')."\n"; # let one of the files have no body if ( $n!=3 ) { for (my $i=1; $i<=$nbdy; $i++) { my $x = int(rand(1000)); my $line = join("\t",'1',$i,'.','A','C','.','.',"DP=$x")."\n"; print $fh $line; $exp .= $line; } } close($fh) or error("close failed: $file.vcf"); } for my $file (@files) { cmd("$$opts{bin}/bcftools view -Ob -o $file.bcf $file.vcf"); cmd("$$opts{bin}/bcftools view -Oz -o $file.vcf.gz $file.vcf"); } my $bcfs = join('.bcf ',@files).'.bcf'; test_cmd($opts,exp=>$exp,out=>"concat.naive.bcf.out",cmd=>"$$opts{bin}/bcftools concat --naive-force $bcfs | $$opts{bin}/bcftools view -H"); my $vcfs = join('.vcf.gz ',@files).'.vcf.gz'; test_cmd($opts,exp=>$exp,out=>"concat.naive.vcf.out",cmd=>"$$opts{bin}/bcftools concat --naive $vcfs | $$opts{bin}/bcftools view -H"); } sub test_mpileup { my ($opts,%args) = @_; if ($args{test_list}) { # make a local copy, create bams, index the bams and the reference open(my $fh1,'>',"$$opts{tmp}/mpileup.bam.list") or error("$$opts{tmp}/mpileup.bam.list: $!"); open(my $fh2,'>',"$$opts{tmp}/mpileup.cram.list") or error("$$opts{tmp}/mpileup.cram.list: $!"); open(my $fh3,'>',"$$opts{tmp}/mpileup.bam.urllist") or error("$$opts{tmp}/mpileup.bam.urllist: $!"); open(my $fh4,'>',"$$opts{tmp}/mpileup.cram.urllist") or error("$$opts{tmp}/mpileup.cram.urllist: $!"); for my $file (@{$args{in}}) { print $fh1 "$$opts{path}/mpileup/$file.bam\n"; print $fh2 "$$opts{path}/mpileup/$file.cram\n"; my $atmp = $^O =~ /^msys/ ? cygpath("$$opts{path}/mpileup") : abs_path("$$opts{path}/mpileup"); unless ($atmp =~ /^\//) { $atmp = "/$atmp"; } print $fh3 "file://$atmp/$file.bam\n"; print $fh4 "file://$atmp/$file.cram\n"; } close($fh1); close($fh2); close($fh3); close($fh4); } my $ref = exists($args{ref}) ? $args{ref} : "mpileup.ref.fa"; $args{args} =~ s/{PATH}/$$opts{path}/g; for my $fmt ('sam','bam','cram') { if ( $fmt eq 'sam' && ($args{args}=~/-r/ or $args{args}=~/-R/) ) { next; } my @files = (); for my $file (@{$args{in}}) { if ( !-e "$$opts{path}/mpileup/$file.$fmt" ) { next; } push @files, "$$opts{path}/mpileup/$file.$fmt"; } if ( !@files ) { next; } my $files = join(' ',@files); my $grep_hdr = "grep -v ^##bcftools | grep -v ^##reference"; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/$ref $files | $grep_hdr"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/$ref -Ob $files | $$opts{bin}/bcftools view | $grep_hdr"); if ($args{test_list}) { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/$ref -b $$opts{tmp}/mpileup.$fmt.list --no-version | grep -v ^##reference"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/$ref -Ob -b $$opts{tmp}/mpileup.$fmt.urllist | $$opts{bin}/bcftools view | $grep_hdr"); } } } sub test_csq { my ($opts,%args) = @_; $args{cmd} =~ s/{PATH}/$$opts{path}/g; if ( $args{tbcsq} ) { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools csq $args{cmd} $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools query -f'[%TBCSQ\\n]' | perl -pe 's/[\\t,]/\\n/g' | sort"); } else { test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools csq $args{cmd} $$opts{path}/$args{in}.vcf | $$opts{bin}/test/csq/sort-csq | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%EXP\\n%POS\\t%REF\\t%ALT\\t%BCSQ\\n\\n'"); } } sub test_csq_real { my ($opts,%args) = @_; my $dirname = "$$opts{path}/$args{in}"; opendir(my $dh,$dirname) or error("opendir $dirname: $!"); while (my $dir=readdir($dh)) { if ( !($dir=~/^E/) or !-d "$dirname/$dir" ) { next; } my $gff = "$dirname/$dir/$dir.gff"; my $ref = "$dirname/$dir/$dir.fa"; opendir(my $tmp,"$dirname/$dir") or error("opendir: $dirname/$dir: $!"); while (my $file=readdir($tmp)) { if ( $file=~/\.vcf$/ ) { my $bname = $`; my $vcf = "$dirname/$dir/$file"; my $out = "$args{in}/$dir/$bname.txt"; my $outl = "$args{in}/$dir/$bname.txt-l"; my $cmd = undef; my @nsmpl = `$$opts{bin}/bcftools query -l $vcf`; if ( !@nsmpl ) { $cmd = "| $$opts{bin}/test/csq/sort-csq | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%EXP\\n%POS\\t%REF\\t%ALT\\t%BCSQ\\n\\n'"; } else { $cmd = "| $$opts{bin}/bcftools query -f'[%POS\\t%REF\\t%ALT\\t%TBCSQ\\n]\\n'"; } if ( -e "$$opts{path}/$out") { test_cmd($opts,%args,out=>$out,cmd=>"$$opts{bin}/bcftools csq -f $ref -g $gff $vcf $cmd"); } if ( -e "$$opts{path}/$outl" ) { test_cmd($opts,%args,out=>$outl,cmd=>"$$opts{bin}/bcftools csq -l -f $ref -g $gff $vcf $cmd"); } next; } if ( $file=~/\.cmd$/ ) { my @cmd = grep { chomp } `cat $dirname/$dir/$file | grep -v ^#`; my $cmd = join(' ; ', @cmd); $cmd =~ s/{bin}/$$opts{bin}/g; test_cmd($opts,%args,out=>"$args{in}/$dir/$file.out",cmd=>"cd $dirname/$dir && $cmd"); } } closedir($tmp); } closedir($dh); } sub test_plugin_split { my ($opts,%args) = @_; if ( !$$opts{test_plugins} ) { return; } my ($package, $filename, $line, $test)=caller(0); $test =~ s/^.+:://; if ( !exists($args{args}) ) { $args{args} = ''; } $args{args} =~ s/{PATH}/$$opts{path}/g; cmd("export BCFTOOLS_PLUGINS=$$opts{bin}/plugins; $$opts{bin}/bcftools +split $$opts{path}/$args{in}.vcf -o $$opts{tmp}/$args{tmp} $args{args}"); opendir(my $dh,"$$opts{tmp}/$args{tmp}") or failed($opts,$test,"Cannot read $$opts{tmp}/$args{tmp}: $!"); my @files = sort grep { !(/^\./) } readdir($dh); closedir($dh) or failed($opts,$test,"Close failed: $$opts{tmp}/$args{tmp}"); my $files = join(' ',@files); test_cmd($opts,%args, cmd=> "export BCFTOOLS_PLUGINS=$$opts{bin}/plugins; $$opts{bin}/bcftools +split $$opts{path}/$args{in}.vcf -o $$opts{tmp}/$args{tmp} $args{args} " . " && cd $$opts{tmp}/$args{tmp} " . " && for f in $files; do echo \$f; $$opts{bin}/bcftools query -l \$f; $$opts{bin}/bcftools view -H \$f; done" ); } sub test_plugin_scatter { my ($opts,%args) = @_; if ( !$$opts{test_plugins} ) { return; } my ($package, $filename, $line, $test)=caller(0); $test =~ s/^.+:://; if ( !exists($args{args}) ) { $args{args} = ''; } $args{args} =~ s/{PATH}/$$opts{path}/g; cmd("export BCFTOOLS_PLUGINS=$$opts{bin}/plugins; $$opts{bin}/bcftools +scatter $$opts{path}/$args{in}.vcf -o $$opts{tmp}/$args{tmp} $args{args}"); opendir(my $dh,"$$opts{tmp}/$args{tmp}") or failed($opts,$test,"Cannot read $$opts{tmp}/$args{tmp}: $!"); my @files = sort grep { !(/^\./) } readdir($dh); closedir($dh) or failed($opts,$test,"Close failed: $$opts{tmp}/$args{tmp}"); my $files = join(' ',@files); test_cmd($opts,%args,cmd=>"export BCFTOOLS_PLUGINS=$$opts{bin}/plugins; $$opts{bin}/bcftools +scatter $$opts{path}/$args{in}.vcf -o $$opts{tmp}/$args{tmp} $args{args} && cd $$opts{tmp}/$args{tmp} && cat $files | grep -v ^##"); } sub test_roh { my ($opts,%args) = @_; $args{args} =~ s/{PATH}/$$opts{path}/g; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools roh $$opts{path}/$args{in}.vcf.gz $args{args}| grep -v ^#"); } sub test_gtcheck { my ($opts,%args) = @_; bgzip_tabix_vcf($opts,$args{in}); $args{args} =~ s/{PATH}/$$opts{path}/g; if ( exists($args{gts}) ) { bgzip_tabix_vcf($opts,$args{gts}); } my $sort = exists($args{sort}) ? ' | sort' : ''; my $gts = exists($args{gts}) ? qq[-g $$opts{tmp}/$args{gts}.vcf.gz] : ''; my $grep = exists($args{grep}) ? $args{grep} : "grep -v ^INFO $sort"; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools gtcheck $args{args} $$opts{tmp}/$args{in}.vcf.gz $gts | grep -v ^# | $grep"); } sub test_vcf_merge_big { my ($opts,%args) = @_; cmd("mkdir -p $$opts{tmp}/$args{in}"); my $ref = 'A'; my @alts = (); for (my $i=0; $i<$args{nalts}; $i++) { push @alts,'A'.('T' x ($i+1)); } my $nsmpl = int($args{nsmpl}/($args{nfiles}-1)); my $nalts = int($args{nalts}/($args{nfiles}-1)); my $seed = srand(0); open(my $fh,'>',"$$opts{tmp}/$args{in}/list.txt") or error("$$opts{tmp}/$args{in}/list.txt: $!"); my @files; for (my $i=0; $i<$args{nfiles}; $i++) { my @hdr = qw(CHROM POS ID REF ALT QUAL FILTER INFO FORMAT); for (my $j=0; $j<$nsmpl; $j++) { push @hdr,'S'.($i*$nsmpl+$j); } my @alt = (); for (my $j=0; $j<$nalts; $j++) { my $k = int(rand(@alts)); push @alt,$alts[$k]; } my @out = (qw(1 3000 .),$ref,join(',',@alt),qw(. . . GT:PL)); for (my $j=0; $j<$nsmpl; $j++) { my $igt = int(rand($nalts+1)); my $jgt = int(rand($nalts+1)); my @pl = (); for (my $a=0; $a<1+@alt; $a++) { for (my $b=0; $b<=$a; $b++) { push @pl,int(rand(2147483000)); } } my $fmt = "$igt/$jgt:".join(',',@pl); push @out,$fmt; } my $file = "$$opts{tmp}/$args{in}/$i.vcf.gz"; my $cmd = qq[$$opts{bin}/bcftools view -Oz -o $file]; open(my $vcf,"| $cmd") or error("$cmd: $!"); print $vcf qq[##fileformat=VCFv4.3\n]; print $vcf qq[##FORMAT=\n]; print $vcf qq[##FORMAT=\n]; print $vcf qq[##contig=\n]; print $vcf qq[##reference=file:///ref.fa\n]; print $vcf '#'.join("\t",@hdr)."\n"; print $vcf join("\t",@out)."\n"; close($vcf) or error("close failed: $cmd"); cmd(qq[$$opts{bin}/bcftools index $file]); print $fh $file."\n"; } close($fh) or error("close failed: $$opts{tmp}/$args{in}/list.txt"); my $args = exists($args{args}) ? $args{args} : ''; test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools merge --no-version $args -l $$opts{tmp}/$args{in}/list.txt"); test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools merge --no-version $args -l $$opts{tmp}/$args{in}/list.txt -Ou | $$opts{bin}/bcftools view --no-version"); } bcftools-1.21/test/trio-dnm/000077500000000000000000000000001467060157400157725ustar00rootroot00000000000000bcftools-1.21/test/trio-dnm/trio-dnm.1.out000066400000000000000000000006171467060157400204170ustar00rootroot00000000000000 -1.67989e-06 . . 30 0 0 -2.23809e-06 . . 17 0 0 -1.82511e-06 . . 16 0 0 -2.23809e-06 . . 18 0 0 -4.98174e-05 . . 17 0 0 -2.23809e-06 . . 11 0 0 -9.18309 . . 71 0 0 -8.67535 . . 56 0 0 -9.11616 . . 50 0 0 -35.3505 . . 56 0 43 -inf . . 54 51 0 -inf . . 52 0 60 -inf . . 3 0 0 -inf . . 49 45 0 -inf . . 56 0 47 -inf . . 55 0 52 -inf . . 53 0 39 -20.8357 . . 38 50 0 bcftools-1.21/test/trio-dnm/trio-dnm.1.vcf000066400000000000000000000046641467060157400203740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch113/resources/ref/Homo_sapiens/1000Genomes_hs37d5/hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband father mother 1 1 . G A,T . . TP GT:AD:PL 0/2:62,0,27:733,919,3060,0,2141,2060 0/0:35,0,0:0,99,1485,99,1485,1485 0/0:38,0,0:0,102,1530,102,1530,1530 1 2 . G T,A . . TP GT:AD:PL 0/1:67,14,0:257,0,2105,458,2146,2605 0/0:36,0,0:0,99,1485,99,1485,1485 0/0:36,0,0:0,99,1485,99,1485,1485 1 3 . G A . . TP GT:AD:PL 0/1:71,14:241,0,2314 0/0:45,0:0,101,1530 0/0:43,0:0,99,1485 1 4 . C T . . TP GT:AD:PL 0/1:111,24:504,0,3776 0/0:35,0:0,99,1485 0/0:36,0:0,99,1485 1 5 . C A . . TP GT:AD:PL 0/1:30,6:124,0,981 0/0:37,0:0,99,1485 0/0:32,0:0,90,1350 1 8 . A G . . TP GT:AD:PL 0/1:434,52:859,0,18086 0/0:38,0:0,99,1485 0/0:38,0:0,99,1485 2 1 . A G . . UN GT:AD:PL 0/1:2,5:179,0,55 0/0:7,0:0,0,180 0/0:4,0:0,12,148 2 2 . A G . . UN GT:AD:PL 0/1:4,5:159,0,126 0/0:1,0:0,3,39 0/0:4,0:0,9,135 2 3 . A G . . UN GT:AD:PL 0/1:4,4:137,0,107 0/0:6,0:0,18,213 0/0:8,0:0,0,232 3 1 . A G . . FP GT:AD:PL 0/1:7,9:357,0,408 0/0:15,0:0,39,585 0/1:4,3:114,0,550 3 2 . C A . . FP GT:AD:PL 0/1:13,15:453,0,442 0/1:29,30:913,0,1011 0/0:39,0:0,99,1485 3 3 . A G . . FP GT:AD:PL 0/1:11,12:361,0,358 0/0:21,0:0,51,765 0/1:10,15:538,0,292 3 4 . A G,C . . FP GT:PL:AD 0/0:0,255,255,255,255,255:306,11,0 0/0:0,255,255,255,255,255:328,1,1 0/0:0,255,255,255,255,255:318,0,0 3 5 . A G . . FP GT:AD:PL 0/1:33,32:890,0,963 0/1:56,45:1328,0,1809 0/0:36,0:0,99,1485 3 6 . A G . . FP GT:AD:PL 0/1:19,24:737,0,649 0/0:48,0:0,108,1620 0/1:25,22:644,0,836 3 7 . A G . . FP GT:AD:PL 0/1:73,90:2864,0,2197 0/0:42,0:0,99,1485 0/1:69,74:2395,0,2064 3 8 . A G . . FP GT:AD:PL 0/1:115,128:4130,0,3542 0/0:34,0:0,99,1360 0/1:137,89:2571,0,4411 3 9 . A G . . FP GT:AD:PL 0/1:18,11:311,0,627 0/1:3,3:51,0,105 0/0:19,0:0,57,764 bcftools-1.21/test/trio-dnm/trio-dnm.10.1.out000066400000000000000000000000341467060157400206270ustar00rootroot00000000000000 . . 0 0 0 46 . . 0 0 0 46 bcftools-1.21/test/trio-dnm/trio-dnm.10.vcf000066400000000000000000000007741467060157400204520ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mother father proband 1 69 . G GA . . . AD:PL 35,0:0,105,1540 16,0:0,48,720 15,13:489,0,580 1 71 . G GCGGCCTCA . . . AD:PL 35,0:0,105,1540 16,0:0,48,720 15,13:489,0,580 bcftools-1.21/test/trio-dnm/trio-dnm.11.1.out000066400000000000000000000010421467060157400206300ustar00rootroot00000000000000chr1:10000057 DNM=0 . . AD=30,30 0,26 0,26 QS=1116,1116 0,921 0,921 VAF=50 0 0 chr1:10000057 DNM=-0.0953102 . . AD=0,30 0,26 38,0 QS=0,1116 0,921 1364,0 VAF=100 100 0 chr1:10697377 DNM=-5.01188e-10 . . AD=4,10 0,61 0,69 QS=240,566 0,3553 0,409 VAF=29 0 0 chr1:141907033 DNM=-inf . . AD=53,8 79,0 128,7 QS=2673,257 3268,0 5087,438 VAF=13 0 5 chrX:10000804 DNM=-20.5943 . . AD=5,19 7,9 10,0 QS=174,671 255,323 370,0 VAF=79 56 0 chrX:141907033 DNM=-5.98923 . . AD=53,8 79,0 128,7 QS=2673,257 3268,0 5087,238 VAF=13 0 5 bcftools-1.21/test/trio-dnm/trio-dnm.11.2.out000066400000000000000000000010151467060157400206310ustar00rootroot00000000000000chr1:10000057 DNM=-inf . . AD=30,30 0,26 0,26 QS=1116,1116 0,921 0,921 VAF=50 0 0 chr1:10000057 DNM=-inf . . AD=0,30 0,26 38,0 QS=0,1116 0,921 1364,0 VAF=0 0 100 chr1:10697377 DNM=-inf . . AD=4,10 0,61 0,69 QS=240,566 0,3553 0,409 VAF=29 0 0 chr1:141907033 DNM=-inf . . AD=53,8 79,0 128,7 QS=2673,257 3268,0 5087,438 VAF=13 0 5 chrX:10000804 DNM=-inf . . AD=5,19 7,9 10,0 QS=174,671 255,323 370,0 VAF=79 56 0 chrX:141907033 DNM=-inf . . AD=53,8 79,0 128,7 QS=2673,257 3268,0 5087,238 VAF=13 0 5 bcftools-1.21/test/trio-dnm/trio-dnm.11.vcf000066400000000000000000000023331467060157400204440ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch118/humgen/resources/ref/Homo_sapiens/GRCh38_15/Homo_sapiens.GRCh38_15.fa ##contig= ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband father mother chr1 10000057 . C T . . . PL:AD:QS 90,0,255:30,30:1116,1116 255,78,0:0,26:0,921 255,78,0:0,26:0,921 chr1 10000057 . C T . . . PL:AD:QS 255,90,0:0,30:0,1116 255,78,0:0,26:0,921 0,114,255:38,0:1364,0 chr1 10697377 . C T . . . PL:AD:QS 255,0,173:4,10:240,566 255,184,0:0,61:0,3553 255,208,0:0,69:0,409 chr1 141907033 . G A . . . PL:AD:QS 54,0,255:53,8:2673,257 0,238,255:79,0:3268,0 0,188,255:128,7:5087,438 chrX 10000804 . C G . . . PL:AD:QS 255,0,85:5,19:174,671 202,0,157:7,9:255,323 0,30,227:10,0:370,0 chrX 141907033 . G A . . . PL:AD:QS 54,0,255:53,8:2673,257 0,238,255:79,0:3268,0 0,188,255:128,7:5087,238 bcftools-1.21/test/trio-dnm/trio-dnm.2.vcf000066400000000000000000000047321467060157400203710ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch113/resources/ref/Homo_sapiens/1000Genomes_hs37d5/hs37d5.fa #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband father mother 1 1 . G A,T . . TP GT:AD:PL 0/2:62,0,27,0:733,919,3060,0,2141,2060 0/0:35,0,0:0,99,1485,99,1485,1485 0/0:38,0,0:0,102,1530,102,1530,1530 1 2 . G T,A . . TP GT:AD:PL 0/1:67,14,0,0:257,0,2105,458,2146,2605 0/0:36,0,0:0,99,1485,99,1485,1485 0/0:36,0,0:0,99,1485,99,1485,1485 1 3 . G A . . TP GT:AD:PL 0/1:71,14,0:241,0,2314 0/0:45,0:0,101,1530 0/0:43,0:0,99,1485 1 4 . C T . . TP GT:AD:PL 0/1:111,24,0:504,0,3776 0/0:35,0:0,99,1485 0/0:36,0:0,99,1485 1 5 . C A . . TP GT:AD:PL 0/1:30,6,0:124,0,981 0/0:37,0:0,99,1485 0/0:32,0:0,90,1350 1 8 . A G . . TP GT:AD:PL 0/1:434,52,0:859,0,18086 0/0:38,0:0,99,1485 0/0:38,0:0,99,1485 2 1 . A G . . UN GT:AD:PL 0/1:2,5,0:179,0,55 0/0:7,0:0,0,180 0/0:4,0:0,12,148 2 2 . A G . . UN GT:AD:PL 0/1:4,5,0:159,0,126 0/0:1,0:0,3,39 0/0:4,0:0,9,135 2 3 . A G . . UN GT:AD:PL 0/1:4,4,0:137,0,107 0/0:6,0:0,18,213 0/0:8,0:0,0,232 3 1 . A G . . FP GT:AD:PL 0/1:7,9,0,0:357,0,408 0/0:15,0:0,39,585 0/1:4,3:114,0,550 3 2 . C A . . FP GT:AD:PL 0/1:13,15,0:453,0,442 0/1:29,30:913,0,1011 0/0:39,0:0,99,1485 3 3 . A G . . FP GT:AD:PL 0/1:11,12,0:361,0,358 0/0:21,0:0,51,765 0/1:10,15:538,0,292 3 4 . A G,C . . FP GT:PL:AD 0/0:0,255,255,255,255,255:306,11,0,0 0/0:0,255,255,255,255,255:328,1,1 0/0:0,255,255,255,255,255:318,0,0 3 5 . A G . . FP GT:AD:PL 0/1:33,32,0:890,0,963 0/1:56,45:1328,0,1809 0/0:36,0:0,99,1485 3 6 . A G . . FP GT:AD:PL 0/1:19,24,0:737,0,649 0/0:48,0:0,108,1620 0/1:25,22:644,0,836 3 7 . A G . . FP GT:AD:PL 0/1:73,90,0:2864,0,2197 0/0:42,0:0,99,1485 0/1:69,74:2395,0,2064 3 8 . A G . . FP GT:AD:PL 0/1:115,128,0:4130,0,3542 0/0:34,0:0,99,1360 0/1:137,89:2571,0,4411 3 9 . A G . . FP GT:AD:PL 0/1:18,11,0:311,0,627 0/1:3,3:51,0,105 0/0:19,0:0,57,764 bcftools-1.21/test/trio-dnm/trio-dnm.4.1.out000066400000000000000000000000171467060157400205530ustar00rootroot00000000000000 0 . . 55 0 0 bcftools-1.21/test/trio-dnm/trio-dnm.4.2.out000066400000000000000000000000171467060157400205540ustar00rootroot00000000000000 0 . . 55 0 0 bcftools-1.21/test/trio-dnm/trio-dnm.4.vcf000066400000000000000000000014351467060157400203700ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##ALT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband mother father 1 94466455 . C T,<*> 0 . . PL:DP:AD:QS 255,0,255,255,255,255:87:39,48,0:1278,1649,0 0,196,255,196,255,255:65:65,0,0:2151,0,0 0,202,255,202,255,255:67:67,0,0:2211,0,0 bcftools-1.21/test/trio-dnm/trio-dnm.5.1.out000066400000000000000000000000261467060157400205540ustar00rootroot00000000000000 -3.26266 . . 14 0 0 bcftools-1.21/test/trio-dnm/trio-dnm.5.vcf000066400000000000000000000015311467060157400203660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##ALT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband mother father 19 1393268 . C T,A,<*> 0 . . PL:DP:AD:QS 66,0,255,159,255,255,159,255,255,255:36:31,5,0,0:1063,218,0,0 0,202,255,173,255,255,202,255,255,255:68:67,0,1,0:2481,0,32,0 0,138,255,138,255,255,138,255,255,255:46:46,0,0,0:1707,0,0,0 bcftools-1.21/test/trio-dnm/trio-dnm.6.1.out000066400000000000000000000001021467060157400205500ustar00rootroot00000000000000 -5.94778 . . 70 0 0 -5.94778 . . 70 0 0 -13.1802 . . 30 0 0 bcftools-1.21/test/trio-dnm/trio-dnm.6.2.out000066400000000000000000000001371467060157400205610ustar00rootroot00000000000000 -3.16223e-05 . . 70 0 0 1 . . -3.16223e-05 . . 70 0 0 1 . . -5.98923 . . 30 0 0 0 . . bcftools-1.21/test/trio-dnm/trio-dnm.6.vcf000066400000000000000000000023471467060157400203750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband mother father 19 33584985 . C G,<*> 0 . . PL:DP:ADF:ADR:AD:QS 125,0,54,134,75,189:10:2,7,0:1,0,0:3,7,0:85,243,0 0,18,160,18,160,160:6:5,0,0:1,0,0:6,0,0:213,0,0 0,45,231,45,231,231:15:13,0,0:2,0,0:15,0,0:487,0,0 19 33584985 . C G 0 . . PL:DP:ADF:ADR:AD:QS 125,0,54:10:2,7:1,0:3,7:85,243 0,18,160:6:5,0:1,0:6,0:213,0 0,45,231:15:13,0:2,0:15,0:487,0 19 33584985 . C G 0 . . PL:DP:ADF:ADR:AD:QS 125,0,54:10:2,7:1,0:3,7:85,243 160,18,0:6:0,5:0,1:0,6:0,213 231,45,0:15:0,13:0,2:0,15:0,487 bcftools-1.21/test/trio-dnm/trio-dnm.7.1.out000066400000000000000000000000261467060157400205560ustar00rootroot00000000000000 -15.1971 . . 19 0 0 bcftools-1.21/test/trio-dnm/trio-dnm.7.vcf000066400000000000000000000017341467060157400203750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband mother father 1 103484311 . T G,<*> 0 . . PL:DP:ADF:ADR:AD:QS 14,0,97,80,112,143:27:22,5,0:0,0,0:22,5,0:424,111,0 0,54,133,54,133,133:18:18,0,0:0,0,0:18,0,0:375,0,0 0,60,160,60,160,160:20:20,0,0:0,0,0:20,0,0:565,0,0 bcftools-1.21/test/trio-dnm/trio-dnm.8.1.out000066400000000000000000000000531467060157400205570ustar00rootroot00000000000000 . -14.2762 . 0 25 0 . -14.276 . 0 28 0 bcftools-1.21/test/trio-dnm/trio-dnm.8.vcf000066400000000000000000000015011467060157400203660ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=/lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mother proband father 1 44158 . GAATG TAATT,TTATT,TGATG,TAATG . . . AD:PL:QS 14,2,0,0,0:0,26,383,42,389,405,42,389,405,405,11,357,373,373,364:449,25,0,0,0 13,0,0,2,5:18,57,389,57,389,389,33,365,365,359,0,332,332,308,317:412,0,0,33,83 16,0,2,0,0:0,48,452,29,433,427,48,452,433,452,43,447,428,447,444:502,0,28,0,0 1 44158 . GAATG TAATG . . . AD:PL:QS 14,0:0,11,364:449,0 13,5:18,0,317:412,83 16,0:0,43,444:502,0 bcftools-1.21/test/trio-dnm/trio-dnm.9.1.out000066400000000000000000000001511467060157400205570ustar00rootroot00000000000000 . . . . . . . . . . . . . . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . bcftools-1.21/test/trio-dnm/trio-dnm.9.2.out000066400000000000000000000001511467060157400205600ustar00rootroot00000000000000 . . . . . . . . . . . . . . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . 1 . . . . . . . . . . . bcftools-1.21/test/trio-dnm/trio-dnm.9.vcf000066400000000000000000000014411467060157400203720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///lustre/scratch116/vr/ref/human/GRCh37/hs37d5.fa ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT proband mother father 1 9 . G C,CC,CCC,CCCC . . . GT 0/1 2/3 4/0 1 10 . G C . . . GT 0/1 0/1 0/0 1 11 . G C . . . GT 0/1 0/0 0/1 1 12 . G C . . . GT 1/1 0/1 0/1 1 13 . G C,CC,CCC,CCCC . . . GT 4/4 0/4 0/4 1 50 . G C . . . GT 1/1 0/0 1/1 1 51 . G C . . . GT 0/1 0/0 0/0 1 52 . G C . . . GT 0/1 1/1 1/1 1 53 . G C,T . . . GT 0/2 0/1 0/0 1 54 . G C,T,GG,GGG,GGGG . . . GT 1/5 1/3 1/1 X 10 . G C . . . GT 1/1 0/0 0/1 X 11 . G C . . . GT 1 0/0 0/1 X 12 . G C . . . GT 0/1 0/0 0/1 X 12 . G C . . . GT 0/1 0/1 0/0 X 12 . G C . . . GT 0/1 0/0 1/1 bcftools-1.21/test/trio-stats.2.out000066400000000000000000000040241467060157400172430ustar00rootroot00000000000000# CMD line shows the command line used to generate this output # DEF lines define expressions for all tested thresholds # FLT* lines report numbers for every threshold and every trio: # 1) filter id # 2) child # 3) father # 4) mother # 5) number of valid trio genotypes (all trio members pass filters, all non-missing) # 6) number of non-reference trio GTs (at least one trio member carries an alternate allele) # 7) number of DNMs/Mendelian errors # 8) number of novel singleton alleles in the child (counted also as DNM / Mendelian error) # 9) number of untransmitted trio singletons (one alternate allele present in one parent) # 10) number of transmitted trio singletons (one alternate allele present in one parent and the child) # 11) number of transitions, all distinct ALT alleles present in the trio are considered # 12) number of transversions, all distinct ALT alleles present in the trio are considered # 13) overall ts/tv, all distinct ALT alleles present in the trio are considered # 14) number of homozygous DNMs/Mendelian errors (likely genotyping errors) # 15) number of recurrent DNMs/Mendelian errors (non-inherited alleles present in other samples; counts GTs, not sites) TRANSMITTED 20 302 child2 father2 mother2 YES MERR 20 303 child1 father1 mother1 - RECURRENT TRANSMITTED 20 303 child2 father2 mother2 YES MERR 20 304 child1 father1 mother1 HOM RECURRENT TRANSMITTED 20 304 child2 father2 mother2 YES MERR 20 305 child1 father1 mother1 HOM - TRANSMITTED 20 306 child1 father1 mother1 NO TRANSMITTED 20 307 child2 father2 mother2 YES TRANSMITTED 20 308 child2 father2 mother2 YES TRANSMITTED 20 308 child2 father2 mother2 NO MERR 20 309 child1 father1 mother1 - - TRANSMITTED 20 310 child1 father1 mother1 NO TRANSMITTED 20 311 child2 father2 mother2 YES TRANSMITTED 20 312 child1 father1 mother1 YES TRANSMITTED 20 315 child1 father1 mother1 YES TRANSMITTED 20 315 child2 father2 mother2 NO DEF FLT0 all FLT0 child1 father1 mother1 14 12 4 2 2 2 3 9 0.33 2 2 FLT0 child2 father2 mother2 14 11 0 0 2 6 3 9 0.33 0 0 bcftools-1.21/test/trio-stats.2.ped000066400000000000000000000001371467060157400172050ustar00rootroot00000000000000HG00100 child1 father1 mother1 2 0 CEU HG00101 father1 0 0 1 0 CEU HG00102 mother1 0 0 2 0 CEU bcftools-1.21/test/trio-stats.out000066400000000000000000000034011467060157400171010ustar00rootroot00000000000000# CMD line shows the command line used to generate this output # DEF lines define expressions for all tested thresholds # FLT* lines report numbers for every threshold and every trio: # 1) filter id # 2) child # 3) father # 4) mother # 5) number of valid trio genotypes (all trio members pass filters, all non-missing) # 6) number of non-reference trio GTs (at least one trio member carries an alternate allele) # 7) number of DNMs/Mendelian errors # 8) number of novel singleton alleles in the child (counted also as DNM / Mendelian error) # 9) number of untransmitted trio singletons (one alternate allele present in one parent) # 10) number of transmitted trio singletons (one alternate allele present in one parent and the child) # 11) number of transitions, all distinct ALT alleles present in the trio are considered # 12) number of transversions, all distinct ALT alleles present in the trio are considered # 13) overall ts/tv, all distinct ALT alleles present in the trio are considered # 14) number of homozygous DNMs/Mendelian errors (likely genotyping errors) # 15) number of recurrent DNMs/Mendelian errors (non-inherited alleles present in other samples; counts GTs, not sites) MERR 20 303 child1 father1 mother1 - RECURRENT MERR 20 304 child1 father1 mother1 HOM RECURRENT MERR 20 305 child1 father1 mother1 HOM - TRANSMITTED 20 306 child1 father1 mother1 NO TRANSMITTED 20 308 child2 father2 mother2 YES TRANSMITTED 20 308 child2 father2 mother2 NO MERR 20 309 child1 father1 mother1 - - TRANSMITTED 20 310 child1 father1 mother1 NO TRANSMITTED 20 311 child2 father2 mother2 YES TRANSMITTED 20 312 child1 father1 mother1 YES DEF FLT0 all FLT0 child1 father1 mother1 14 12 4 2 2 1 3 9 0.33 2 2 FLT0 child2 father2 mother2 14 11 0 0 1 2 3 9 0.33 0 0 bcftools-1.21/test/trio-stats.ped000066400000000000000000000002761467060157400170510ustar00rootroot00000000000000HG00100 child1 father1 mother1 2 0 CEU HG00101 father1 0 0 1 0 CEU HG00102 mother1 0 0 2 0 CEU HG00200 child2 father2 mother2 2 0 CEU HG00201 father2 0 0 1 0 CEU HG00202 mother2 0 0 2 0 CEU bcftools-1.21/test/trio-stats.vcf000066400000000000000000000016261467060157400170570ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT child1 father1 mother1 child2 father2 mother2 20 302 . T TA . . . GT 0/1 0/0 1/1 0/1 1/0 1/1 20 303 . T C . . . GT 0/1 1/1 1/1 0/1 1/0 1/1 20 304 . T A . . . GT 0/0 0/1 1/1 0/1 1/0 1/1 20 305 . T A . . . GT 1/1 0/0 0/0 0/0 0/0 0/0 20 306 . T A . . . GT 0/0 0/1 0/0 0/0 0/0 0/0 20 307 . T A . . . GT 0/1 1/0 0/1 0/1 1/0 0/0 20 308 . T A,C . . . GT 0/0 0/0 0/0 0/1 1/2 0/0 20 309 . T A,C . . . GT 1/2 1/1 1/1 1/1 1/1 1/1 20 310 . T A,C . . . GT 1/1 1/2 1/1 1/1 1/1 1/1 20 311 . T A,C . . . GT 1/1 1/1 1/1 1/2 2/1 1/1 20 312 . TAA T . . . GT 0/1 1/0 0/0 0/0 0/0 0/0 20 313 . A C,* . . . GT 0/2 2/0 0/0 0/0 1/0 1/0 20 314 . A C,* . . . GT 1/2 2/0 1/0 0/0 1/0 1/0 20 315 . A C . . . GT 1/0 1/1 1/0 1/1 1/0 1/1 bcftools-1.21/test/trio.out000066400000000000000000000006001467060157400157430ustar00rootroot00000000000000# # TRIO [2]Father [3]Mother [4]Child [5]nTested [6]nMendelian Errors [7]nSwitch [8]nSwitch (%) TRIO HG00101 HG00102 HG00100 5 4 0 0.00 TRIO HG00201 HG00202 HG00200 11 0 2 18.18 # POP population or other grouping defined by an optional 7-th column of the PED file # POP [2]Name [3]Number of trios [4]avgTested [5]avgMendelian Errors [6]avgSwitch [7]avgSwitch (%) POP CEU 2 8 2 1 9.09 bcftools-1.21/test/trio.ped000066400000000000000000000003001467060157400157010ustar00rootroot00000000000000HG00100 HG00100 HG00101 HG00102 2 0 CEU HG00101 HG00101 0 0 1 0 CEU HG00102 HG00102 0 0 2 0 CEU HG00200 HG00200 HG00201 HG00202 2 0 CEU HG00201 HG00201 0 0 1 0 CEU HG00202 HG00202 0 0 2 0 CEU bcftools-1.21/test/trio.vcf000066400000000000000000000014361467060157400157220ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 HG00200 HG00201 HG00202 20 302 . T TA 999 . . GT 0|1 1|0 1|1 0|1 1|0 1|1 20 828 . T C 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 20 834 . G A 999 . . GT 0|1 0|1 1|1 1|0 1|0 1|1 20 1665 . T C 999 . . GT 1|0 0|1 0|1 0|1 1|0 1|1 20 1869 . A T 999 . . GT 0|1 0|0 1|1 0|1 1|0 1|1 20 2041 . G A 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 20 2220 . G A 999 . . GT 0|1 1|0 1|1 0|1 1|0 1|1 20 2564 . A G 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 20 3104 . C T 999 . . GT 0|0 0|0 0|1 0|1 1|0 1|1 20 3587 . G A 999 . . GT 0|1 0|1 1|1 0|1 1|0 1|1 20 3936 . A G 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 bcftools-1.21/test/variant-distance.1.out000066400000000000000000000010131467060157400203600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 101 . T A . . DIST=3 1 101 . T C . . DIST=3 1 104 . T A . . DIST=3 1 104 . T C . . DIST=3 1 108 . T A . . DIST=4 1 108 . T C . . DIST=4 1 115 . T A . . DIST=7 2 120 . T A . . DIST=10 2 130 . T A . . DIST=10 bcftools-1.21/test/variant-distance.2.out000066400000000000000000000007751467060157400203770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 101 . T A . . DIST=3 1 101 . T C . . DIST=3 1 104 . T A . . DIST=4 1 104 . T C . . DIST=4 1 108 . T A . . DIST=7 1 108 . T C . . DIST=7 1 115 . T A . . . 2 120 . T A . . DIST=10 2 130 . T A . . . bcftools-1.21/test/variant-distance.3.out000066400000000000000000000007741467060157400203770ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 101 . T A . . . 1 101 . T C . . . 1 104 . T A . . DIST=3 1 104 . T C . . DIST=3 1 108 . T A . . DIST=4 1 108 . T C . . DIST=4 1 115 . T A . . DIST=7 2 120 . T A . . . 2 130 . T A . . DIST=10 bcftools-1.21/test/variant-distance.4.out000066400000000000000000000010471467060157400203720ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 1 101 . T A . . DIST=0,3 1 101 . T C . . DIST=0,3 1 104 . T A . . DIST=3,4 1 104 . T C . . DIST=3,4 1 108 . T A . . DIST=4,7 1 108 . T C . . DIST=4,7 1 115 . T A . . DIST=7,0 2 120 . T A . . DIST=0,10 2 130 . T A . . DIST=10,0 bcftools-1.21/test/variant-distance.vcf000066400000000000000000000005231467060157400201750ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file://some/path/human_g1k_v37.fasta ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 101 . T A . . . 1 101 . T C . . . 1 104 . T A . . . 1 104 . T C . . . 1 108 . T A . . . 1 108 . T C . . . 1 115 . T A . . . 2 120 . T A . . . 2 130 . T A . . . bcftools-1.21/test/variantkey-hex.out000066400000000000000000000000561467060157400177320ustar00rootroot00000000000000VariantKeys: 66 Non-reversible VariantKeys: 3 bcftools-1.21/test/vcf2sex.out000066400000000000000000000000201467060157400163420ustar00rootroot00000000000000MALE M FEMALE F bcftools-1.21/test/vcf2sex.vcf000066400000000000000000000015331467060157400163230ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT MALE FEMALE X 1 . C A . PASS . GT 1 0/1 X 12000 . C A . PASS . GT 0 0/1 X 24000 . C A . PASS . GT 1 0/1 X 36000 . C A . PASS . GT 0 0/1 X 48000 . C A . PASS . GT 1 0/1 X 60000 . C A . PASS . GT 0 0/1 X 100000 . C A . PASS . GT 0/1 0/1 X 2699521 . C A . PASS . GT 0 0/1 X 33145825 . C A . PASS . GT 1 0/1 X 63592129 . C A . PASS . GT 1 0/1 X 94038433 . C A . PASS . GT 0 0/1 X 124484737 . C A . PASS . GT 0 0/1 X 154931043 . C A . PASS . GT 0/1 0/1 Y 1 . C A . PASS . GT 0 . Y 11874713 . C A . PASS . GT 0 . Y 23749426 . C A . PASS . GT 0 . Y 35624139 . C A . PASS . GT 0 . Y 47498852 . C A . PASS . GT 0 . Y 59373565 . C A . PASS . GT 0 . bcftools-1.21/test/view-a.1.out000066400000000000000000000002131467060157400163150ustar00rootroot00000000000000chr1 36 . A C . . AC=2;AN=6 GT:GQ:MIN_DP:PL:DP:AD:VAF:DNM:VA 0/0:1:0:0,.,.:.:.:.:1:0 1/1:8:.:28,7,0:10:0,10:1:.:. 0/0:18:6:0,.,.:.:.:.:.:. bcftools-1.21/test/view-a.vcf000066400000000000000000000023131467060157400161300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##contig= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT EGAN00001406653 EGAN00001405940 EGAN00001406033 chr1 36 . A <*>,C . . . GT:GQ:MIN_DP:PL:DP:AD:VAF:DNM:VA 0/0:1:0:0,0,0,.,.,.:.:.:.:1:0 2/2:8:.:28,990,990,7,990,0:10:0,0,10:0,1:.:. 0/0:18:6:0,18,179,.,.,.:.:.:.:.:. bcftools-1.21/test/view-t.1.out000066400000000000000000000000401467060157400163360ustar00rootroot000000000000002 1 . A C . . . 2 2 . A C . . . bcftools-1.21/test/view-t.2.out000066400000000000000000000000201467060157400163350ustar00rootroot000000000000003 2 . A C . . . bcftools-1.21/test/view-t.vcf000066400000000000000000000003371467060157400161570ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . A C . . . 2 1 . A C . . . 2 2 . A C . . . 3 2 . A C . . . bcftools-1.21/test/view.1.out000066400000000000000000000072671467060157400161170ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00002 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=2;AC=1 GT:PL:DP:GQ 0/1:140,0,255:71:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=2;AC=1 GT:PL:DP:GQ 0/1:192,0,255:82:99 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=2;AC=1 GT:PL:DP:GQ 0|1:192,0,255:13:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=1;AC=1 GT:PL:DP:GQ 1:255,0:33:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=1;AC=1 GT:PL:DP:GQ 1:255,0:33:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=1;AC=1 GT:PL:DP:GQ 1:255,0:64:99 Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=1;AC=1 GT:PL:DP:GQ 1:95,0:130:99 bcftools-1.21/test/view.10.out000066400000000000000000000060541467060157400161700ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. bcftools-1.21/test/view.2.out000066400000000000000000000060521467060157400161070ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00003 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;AC=2;AN=2 GT:PL:DP:GQ 1/1:255,255,0:182:99 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=2;AC=2 GT:PL:DP:GQ 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=2;AC=2 GT:PL:DP:GQ 1/1:255,235,0:78:99 bcftools-1.21/test/view.3.out000066400000000000000000000055211467060157400161100ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00003 X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=2;AC=1 GT:PL:DP:GQ 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=2;AC=1 GT:PL:DP:GQ 0/1:255,255,255:62:99 bcftools-1.21/test/view.4.out000066400000000000000000000056601467060157400161150ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 bcftools-1.21/test/view.5.out000066400000000000000000000064201467060157400161110ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. bcftools-1.21/test/view.6.out000066400000000000000000000112321467060157400161070ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 bcftools-1.21/test/view.7.out000066400000000000000000000050001467060157400161040ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 bcftools-1.21/test/view.8.out000066400000000000000000000001371467060157400161130ustar00rootroot0000000000000011 5464562 . C T 999 PASS DP=0;AC=0;AN=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. bcftools-1.21/test/view.9.out000066400000000000000000000052641467060157400161220ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO 11 2343543 . A . 999 PASS DP=100223 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 bcftools-1.21/test/view.GL-GP.vcf000066400000000000000000000057621467060157400165320ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS . GL:GP 0:1 0:1 0:1 11 5464562 . C T 999 PASS . GL:GP 0,0,0:0.333333,0.333333,0.333333 0,0,0:0.333333,0.333333,0.333333 0,0,0:0.333333,0.333333,0.333333 20 76962 rs6111385 T C 999 PASS . GL:GP -25.5,0,-25.5:3.16228e-26,1,3.16228e-26 -25.5,-25.5,0:3.16228e-26,3.16228e-26,1 -25.5,-25.5,0:3.16228e-26,3.16228e-26,1 20 126310 . ACC A 999 StrandBias;EndDistBias . GL:GP -25.5,0,-13.2:3.16228e-26,1,6.30958e-14 -25.5,0,-13.9:3.16228e-26,1,1.25893e-14 -25.5,-21.3,0:3.16228e-26,5.01188e-22,1 20 138125 rs2298108 G T 999 PASS . GL:GP -13.5,0,-16.3:3.16228e-14,1,5.01188e-17 -14,0,-25.5:1e-14,1,3.16228e-26 -25.5,-19.9,0:3.16228e-26,1.25893e-20,1 20 138148 rs2298109 C T 999 PASS . GL:GP -19.5,0,-25.5:3.16228e-20,1,3.16228e-26 -19.2,0,-25.5:6.30956e-20,1,3.16228e-26 -25.5,-23.5,0:3.16228e-26,3.16228e-24,1 20 271225 . T TTTA,TA 999 StrandBias . GL:GP -15.1,-5.3,-20.3,0,-5.2,-15.9:7.94319e-16,5.01181e-06,5.01182e-21,0.999989,6.3095e-06,1.25891e-16 -25.5,0,-21.3,-25.5,-25.5,-25.5:3.16228e-26,1,5.01188e-22,3.16228e-26,3.16228e-26,3.16228e-26 -25.5,-25.5,-25.5,-25.5,0,-24.1:3.16228e-26,3.16228e-26,3.16228e-26,3.16228e-26,1,7.94328e-25 20 304568 . C T 999 PASS . GL:GP -9.5,0,-25.5:3.16228e-10,1,3.16228e-26 -19.2,0,-25.5:6.30956e-20,1,3.16228e-26 -25.5,-9.5,0:3.16228e-26,3.16228e-10,1 20 326891 . A AC 999 PASS . GL:GP -25.5,0,-13.2:3.16228e-26,1,6.30958e-14 -25.5,0,-13.9:3.16228e-26,1,1.25893e-14 .,.,.:.,.,. X 2928329 rs62584840 C T 999 PASS . GL:GP 0,-5.6:0.999997,2.51188e-06 0,-8.1:1,7.94328e-09 -7.3,0,-1.9:4.94956e-08,0.987567,0.0124327 X 2933066 rs61746890 G C 999 PASS . GL:GP 0,-25.5:1,3.16228e-26 0,-25.5:1,3.16228e-26 -25.5,-25.5,-25.5:0.333333,0.333333,0.333333 X 2942109 rs5939407 T C 999 PASS . GL:GP 0,-25.5:1,3.16228e-26 -25.5,0:3.16228e-26,1 -25.5,-15.7,0:3.16228e-26,1.99526e-16,1 X 3048719 . T C 999 PASS . GL:GP 0,-25.5:1,3.16228e-26 -25.5,0:3.16228e-26,1 -25.5,0,-15.7:3.16228e-26,1,1.99526e-16 Y 8657215 . C A 999 PASS . GL:GP 0,-25.5:1,3.16228e-26 -25.5,0:3.16228e-26,1 .:. Y 10011673 rs78249411 G A 999 MinAB . GL:GP -12.6,-10.1:0.00315231,0.996848 -9.5,0:3.16228e-10,1 .:. bcftools-1.21/test/view.GL.vcf000066400000000000000000000036031467060157400162160ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS . GL 0 0 0 11 5464562 . C T 999 PASS . GL 0,0,0 0,0,0 0,0,0 20 76962 rs6111385 T C 999 PASS . GL -25.5,0,-25.5 -25.5,-25.5,0 -25.5,-25.5,0 20 126310 . ACC A 999 StrandBias;EndDistBias . GL -25.5,0,-13.2 -25.5,0,-13.9 -25.5,-21.3,0 20 138125 rs2298108 G T 999 PASS . GL -13.5,0,-16.3 -14,0,-25.5 -25.5,-19.9,0 20 138148 rs2298109 C T 999 PASS . GL -19.5,0,-25.5 -19.2,0,-25.5 -25.5,-23.5,0 20 271225 . T TTTA,TA 999 StrandBias . GL -15.1,-5.3,-20.3,0,-5.2,-15.9 -25.5,0,-21.3,-25.5,-25.5,-25.5 -25.5,-25.5,-25.5,-25.5,0,-24.1 20 304568 . C T 999 PASS . GL -9.5,0,-25.5 -19.2,0,-25.5 -25.5,-9.5,0 20 326891 . A AC 999 PASS . GL -25.5,0,-13.2 -25.5,0,-13.9 .,.,. X 2928329 rs62584840 C T 999 PASS . GL 0,-5.6 0,-8.1 -7.3,0,-1.9 X 2933066 rs61746890 G C 999 PASS . GL 0,-25.5 0,-25.5 -25.5,-25.5,-25.5 X 2942109 rs5939407 T C 999 PASS . GL 0,-25.5 -25.5,0 -25.5,-15.7,0 X 3048719 . T C 999 PASS . GL 0,-25.5 -25.5,0 -25.5,0,-15.7 Y 8657215 . C A 999 PASS . GL 0,-25.5 -25.5,0 . Y 10011673 rs78249411 G A 999 MinAB . GL -12.6,-10.1 -9.5,0 . bcftools-1.21/test/view.GP.vcf000066400000000000000000000045271467060157400162300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 22 16050159 . C T 68 . . GP 0.962,0.038,0 0,1,0 1,0,0 22 16050252 . A T 85 . . GP 0.934,0.059,0.007 0,1,0 1,0,0 22 16051249 . T C 32.1761 . . GP 0,1,0 1,0,0 1,0,0 22 16051347 . G C 283 . . GP 0,0.443,0.557 0,1,0 1,0,0 22 16051453 . A C 3.42882 . . GP 0.001,0.999,0 1,0,0 1,0,0 22 16051497 . A G 362 . . GP 0,0.008,0.992 0,1,0 1,0,0 22 16051968 . C A 136 . . GP 0.972,0.024,0.003 0,1,0 1,0,0 22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GP 0.333,0.333,0.333 0,0,1 1,0,0 22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GP 0.003,0.995,0.002 0,1,0 1,0,0 22 16052180 . AAAC AAACCAACTAAC 221 . . GP 0.909,0.091,0 0,1,0 1,0,0 22 16052239 . A G 172 . . GP 0.984,0.016,0 0,1,0 1,0,0 22 16052513 . G C 153 . . GP 1,0,0 0,1,0 1,0,0 22 16052618 . G A 124 . . GP 0.997,0.003,0 0,1,0 1,0,0 22 16053659 . A C 352 . . GP 0,0.002,0.998 0,0,1 1,0,0 22 16053791 . C A 287 . . GP 0,1,0 0,1,0 1,0,0 22 16054454 . C T 14.2772 . . GP 0,0.76,0.24 1,0,0 1,0,0 22 16054667 . C G 179 . . GP 0.998,0.002,0 0,1,0 1,0,0 22 16054740 . A G 126 . . GP 0.994,0.006,0 0,1,0 1,0,0 22 16055942 . C T 385 . . GP 0,0.008,0.992 0,0,1 1,0,0 22 16056126 . G A 263 . . GP 0,0.969,0.031 0,1,0 1,0,0 22 16056854 . G GA 17.3105 . . GP 0.996,0.004,0 0,1,0 1,0,0 22 16057248 . G A 167 . . GP 0.988,0.012,0 0,1,0 1,0,0 22 16057320 . G A 20.0168 . . GP 0,0.998,0.002 1,0,0 1,0,0 22 16057417 . C T 16.3704 . . GP 0,1,0 1,0,0 1,0,0 22 16058070 . A G 452 . . GP 0,0,1 0,0,1 0,0,1 22 16058415 . A G 212 . . GP 0.997,0.003,0 0,0,1 1,0,0 22 16058463 . C T 136 . . GP 0,0.666,0.334 1,0,0 1,0,0 22 16058758 . C A 107 . . GP 0,0.166,0.834 1,0,0 1,0,0 22 16058766 . G A 15.517 . . GP 0.999,0.001,0 0,0.201,0.799 1,0,0 22 16058852 . A T 198 . . GP 0,0.112,0.888 0,0,1 1,0,0 22 16058883 . A G 129 . . GP 0,0.334,0.666 0,0,1 1,0,0 22 16059081 . A G 212 . . GP 0.984,0.016,0 0,0,1 1,0,0 22 16059734 . C T 114 . . GP 0,0.038,0.962 1,0,0 1,0,0 22 16059753 . A T 212 . . GP 0.998,0.002,0 0,0,1 1,0,0 Y 16059973 . C A 195 . . GP 0.975,0.025 1,0 0,1 Y 16060178 . G A 187 . . GP 0.969,0.031 0,1 0.5,0.5 bcftools-1.21/test/view.GT.vcf000066400000000000000000000035111467060157400162240ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 22 16050159 . C T 68 . . GT 0/0 0/1 0/0 22 16050252 . A T 85 . . GT 0/0 0/1 0/0 22 16051249 . T C 32.1761 . . GT 0/1 0/0 0/0 22 16051347 . G C 283 . . GT ./. 0/1 0/0 22 16051453 . A C 3.42882 . . GT 0/1 0/0 0/0 22 16051497 . A G 362 . . GT 1/1 0/1 0/0 22 16051968 . C A 136 . . GT 0/0 0/1 0/0 22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GT ./. 1/1 0/0 22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GT 0/1 0/1 0/0 22 16052180 . AAAC AAACCAACTAAC 221 . . GT 0/0 0/1 0/0 22 16052239 . A G 172 . . GT 0/0 0/1 0/0 22 16052513 . G C 153 . . GT 0/0 0/1 0/0 22 16052618 . G A 124 . . GT 0/0 0/1 0/0 22 16053659 . A C 352 . . GT 1/1 1/1 0/0 22 16053791 . C A 287 . . GT 0/1 0/1 0/0 22 16054454 . C T 14.2772 . . GT ./. 0/0 0/0 22 16054667 . C G 179 . . GT 0/0 0/1 0/0 22 16054740 . A G 126 . . GT 0/0 0/1 0/0 22 16055942 . C T 385 . . GT 1/1 1/1 0/0 22 16056126 . G A 263 . . GT 0/1 0/1 0/0 22 16056854 . G GA 17.3105 . . GT 0/0 0/1 0/0 22 16057248 . G A 167 . . GT 0/0 0/1 0/0 22 16057320 . G A 20.0168 . . GT 0/1 0/0 0/0 22 16057417 . C T 16.3704 . . GT 0/1 0/0 0/0 22 16058070 . A G 452 . . GT 1/1 1/1 1/1 22 16058415 . A G 212 . . GT 0/0 1/1 0/0 22 16058463 . C T 136 . . GT ./. 0/0 0/0 22 16058758 . C A 107 . . GT 1/1 0/0 0/0 22 16058766 . G A 15.517 . . GT 0/0 ./. 0/0 22 16058852 . A T 198 . . GT 1/1 1/1 0/0 22 16058883 . A G 129 . . GT ./. 1/1 0/0 22 16059081 . A G 212 . . GT 0/0 1/1 0/0 22 16059734 . C T 114 . . GT 1/1 0/0 0/0 22 16059753 . A T 212 . . GT 0/0 1/1 0/0 Y 16059973 . C A 195 . . GT 0 0 1 Y 16060178 . G A 187 . . GT 0 1 . bcftools-1.21/test/view.GTisec.H.out000066400000000000000000000013141467060157400173060ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # Human readable output (-H) was requested. Subset intersection counts are therefore sorted by # sample and repeated for each contained sample. For each sample, counts are in banker's # sequence order regarding all other samples. # [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) 9 NA00003 1 NA00003,NA00002 0 NA00003,NA00001 1 NA00003,NA00002,NA00001 4 NA00002 1 NA00002,NA00003 8 NA00002,NA00001 1 NA00002,NA00003,NA00001 5 NA00001 0 NA00001,NA00003 8 NA00001,NA00002 1 NA00001,NA00003,NA00002 bcftools-1.21/test/view.GTisec.Hm.out000066400000000000000000000015421467060157400174660ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # The first line of each sample contains its count of missing genotypes, with a '-' appended # to the sample name. # Human readable output (-H) was requested. Subset intersection counts are therefore sorted by # sample and repeated for each contained sample. For each sample, counts are in banker's # sequence order regarding all other samples. # [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) 4 NA00003- 9 NA00003 1 NA00003,NA00002 0 NA00003,NA00001 1 NA00003,NA00002,NA00001 1 NA00002- 4 NA00002 1 NA00002,NA00003 8 NA00002,NA00001 1 NA00002,NA00003,NA00001 1 NA00001- 5 NA00001 0 NA00001,NA00003 8 NA00001,NA00002 1 NA00001,NA00003,NA00002 bcftools-1.21/test/view.GTisec.Hmv.out000066400000000000000000000015421467060157400176540ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # The first line of each sample contains its count of missing genotypes, with a '-' appended # to the sample name. # Human readable output (-H) was requested. Subset intersection counts are therefore sorted by # sample and repeated for each contained sample. For each sample, counts are in banker's # sequence order regarding all other samples. # [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) 4 NA00003- 9 NA00003 1 NA00003,NA00002 0 NA00003,NA00001 1 NA00003,NA00002,NA00001 1 NA00002- 4 NA00002 1 NA00002,NA00003 8 NA00002,NA00001 1 NA00002,NA00003,NA00001 1 NA00001- 5 NA00001 0 NA00001,NA00003 8 NA00001,NA00002 1 NA00001,NA00003,NA00002 bcftools-1.21/test/view.GTisec.Hv.out000066400000000000000000000013141467060157400174740ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # Human readable output (-H) was requested. Subset intersection counts are therefore sorted by # sample and repeated for each contained sample. For each sample, counts are in banker's # sequence order regarding all other samples. # [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) 9 NA00003 1 NA00003,NA00002 0 NA00003,NA00001 1 NA00003,NA00002,NA00001 4 NA00002 1 NA00002,NA00003 8 NA00002,NA00001 1 NA00002,NA00003,NA00001 5 NA00001 0 NA00001,NA00003 8 NA00001,NA00002 1 NA00001,NA00003,NA00002 bcftools-1.21/test/view.GTisec.m.out000066400000000000000000000011471467060157400173570ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # The first 3 lines contain the counts for missing values of each sample in the order provided # in the SMPS-line above. Intersection counts only start afterwards. # Subset intersection counts are in global banker's sequence order. # After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: # NA00003,NA00002 NA00003,NA00001 ... # [1] Number of shared non-ref genotypes 4 1 1 9 4 5 1 0 8 1 bcftools-1.21/test/view.GTisec.mv.out000066400000000000000000000014151467060157400175430ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # The first 3 lines contain the counts for missing values of each sample in the order provided # in the SMPS-line above. Intersection counts only start afterwards. # Subset intersection counts are in global banker's sequence order. # After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: # NA00003,NA00002 NA00003,NA00001 ... # [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) 4 NA00003- 1 NA00002- 1 NA00001- 9 NA00003 4 NA00002 5 NA00001 1 NA00003,NA00002 0 NA00003,NA00001 8 NA00002,NA00001 1 NA00003,NA00002,NA00001 bcftools-1.21/test/view.GTisec.out000066400000000000000000000006731467060157400171270ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # Subset intersection counts are in global banker's sequence order. # After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: # NA00003,NA00002 NA00003,NA00001 ... # [1] Number of shared non-ref genotypes 9 4 5 1 0 8 1 bcftools-1.21/test/view.GTisec.v.out000066400000000000000000000011061467060157400173630ustar00rootroot00000000000000# This file can be used as input to the subset plotting tools at: # https://github.com/dlaehnemann/bankers2 # Genotype intersections across samples: @SMPS NA00003 NA00002 NA00001 # Subset intersection counts are in global banker's sequence order. # After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: # NA00003,NA00002 NA00003,NA00001 ... # [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) 9 NA00003 4 NA00002 5 NA00001 1 NA00003,NA00002 0 NA00003,NA00001 8 NA00002,NA00001 1 NA00003,NA00002,NA00001 bcftools-1.21/test/view.GTsubset.NA1.out000066400000000000000000000072111467060157400200620ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. bcftools-1.21/test/view.GTsubset.NA1NA2.out000066400000000000000000000104371467060157400203670ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. bcftools-1.21/test/view.GTsubset.NA1NA2NA3.out000066400000000000000000000061171467060157400206710ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. bcftools-1.21/test/view.PL.vcf000066400000000000000000000033611467060157400162300ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS . PL 0 0 0 11 5464562 . C T 999 PASS . PL 0,0,0 0,0,0 0,0,0 20 76962 rs6111385 T C 999 PASS . PL 255,0,255 255,255,0 255,255,0 20 126310 . ACC A 999 StrandBias;EndDistBias . PL 255,0,132 255,0,139 255,213,0 20 138125 rs2298108 G T 999 PASS . PL 135,0,163 140,0,255 255,199,0 20 138148 rs2298109 C T 999 PASS . PL 195,0,255 192,0,255 255,235,0 20 271225 . T TTTA,TA 999 StrandBias . PL 151,53,203,0,52,159 255,0,213,255,255,255 255,255,255,255,0,241 20 304568 . C T 999 PASS . PL 95,0,255 192,0,255 255,95,0 20 326891 . A AC 999 PASS . PL 255,0,132 255,0,139 .,.,. X 2928329 rs62584840 C T 999 PASS . PL 0,56 0,81 73,0,19 X 2933066 rs61746890 G C 999 PASS . PL 0,255 0,255 255,255,255 X 2942109 rs5939407 T C 999 PASS . PL 0,255 255,0 255,157,0 X 3048719 . T C 999 PASS . PL 0,255 255,0 255,0,157 Y 8657215 . C A 999 PASS . PL 0,255 255,0 . Y 10011673 rs78249411 G A 999 MinAB . PL 126,101 95,0 . bcftools-1.21/test/view.chrs.out000066400000000000000000000055261467060157400167120ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA BBB Pf3D7_01_v3 1 . A T . . . GT . . Pf3D7_01_v3 2 . A G . . . GT . . Pf3D7_01_v3 33 . T A . . . GT . . Pf3D7_01_v3 36 . A G . . . GT . . Pf3D7_01_v3 57 . C T . . . GT . . Pf3D7_01_v3 61 . A T . . . GT . . Pf3D7_01_v3 72 . T C,A . . . GT . . Pf3D7_01_v3 73 . T A . . . GT . . Pf3D7_01_v3 74 . A T,C . . . GT . . Pf3D7_01_v3 84 . C T . . . GT . . Pf3D7_01_v3 110 . T A . . . GT . . Pf3D7_01_v3 111 . T A . . . GT . . Pf3D7_01_v3 129 . T A . . . GT . . Pf3D7_01_v3 146 . A C,T . . . GT . . Pf3D7_01_v3 147 . A C,T . . . GT . . Pf3D7_01_v3 152 . G T . . . GT . . Pf3D7_01_v3 168 . T A . . . GT . . Pf3D7_01_v3 169 . A G . . . GT . . Pf3D7_01_v3 175 . A T . . . GT . . Pf3D7_01_v3 195 . T A . . . GT . . Pf3D7_01_v3 196 . A C . . . GT . . Pf3D7_01_v3 199 . T C . . . GT . . Pf3D7_01_v3 204 . C T . . . GT . . Pf3D7_01_v3 213 . G A . . . GT . . Pf3D7_01_v3 222 . A G . . . GT . . Pf3D7_01_v3 223 . A G . . . GT . . Pf3D7_01_v3 227 . T A . . . GT . . Pf3D7_02_v3 90 . C T . . . GT . . Pf3D7_02_v3 100 . T A . . . GT . . Pf3D7_02_v3 111 . T A . . . GT . . Pf3D7_02_v3 129 . T A . . . GT . . Pf3D7_02_v3 146 . A C,T . . . GT . . Pf3D7_02_v3 147 . A C,T . . . GT . . Pf3D7_02_v3 152 . G T . . . GT . . Pf3D7_02_v3 168 . T A . . . GT . . Pf3D7_02_v3 169 . A G . . . GT . . Pf3D7_02_v3 175 . A T . . . GT . . Pf3D7_02_v3 195 . T A . . . GT . . Pf3D7_02_v3 196 . A C . . . GT . . Pf3D7_02_v3 199 . T C . . . GT . . Pf3D7_02_v3 204 . C T . . . GT . . Pf3D7_02_v3 213 . G A . . . GT . . Pf3D7_02_v3 222 . A G . . . GT . . Pf3D7_02_v3 223 . A G . . . GT . . Pf3D7_02_v3 227 . T A . . . GT . . Pf3D7_02_v3 235 . A G . . . GT . . Pf3D7_03_v3 1 . A T . . . GT . . Pf3D7_03_v3 2 . A G . . . GT . . Pf3D7_03_v3 33 . T A . . . GT . . Pf3D7_03_v3 36 . A G . . . GT . . Pf3D7_03_v3 57 . C T . . . GT . . Pf3D7_03_v3 61 . A T . . . GT . . Pf3D7_03_v3 72 . T C,A . . . GT . . Pf3D7_03_v3 73 . T A . . . GT . . Pf3D7_03_v3 74 . A T,C . . . GT . . Pf3D7_03_v3 84 . C T . . . GT . . Pf3D7_03_v3 110 . T A . . . GT . . Pf3D7_03_v3 111 . T A . . . GT . . Pf3D7_03_v3 129 . T A . . . GT . . Pf3D7_03_v3 146 . A C,T . . . GT . . Pf3D7_03_v3 147 . A C,T . . . GT . . Pf3D7_03_v3 152 . G T . . . GT . . Pf3D7_03_v3 168 . T A . . . GT . . Pf3D7_03_v3 169 . A G . . . GT . . Pf3D7_03_v3 175 . A T . . . GT . . Pf3D7_03_v3 195 . T A . . . GT . . Pf3D7_03_v3 196 . A C . . . GT . . Pf3D7_03_v3 199 . T C . . . GT . . Pf3D7_03_v3 204 . C T . . . GT . . Pf3D7_03_v3 213 . G A . . . GT . . Pf3D7_03_v3 222 . A G . . . GT . . Pf3D7_03_v3 223 . A G . . . GT . . Pf3D7_03_v3 227 . T A . . . GT . . Pf3D7_03_v3 235 . A G . . . GT . . bcftools-1.21/test/view.chrs.tab000066400000000000000000000022071467060157400166420ustar00rootroot00000000000000Pf3D7_01_v3 1 Pf3D7_01_v3 2 Pf3D7_01_v3 33 Pf3D7_01_v3 36 Pf3D7_01_v3 57 Pf3D7_01_v3 61 Pf3D7_01_v3 72 Pf3D7_01_v3 73 Pf3D7_01_v3 74 Pf3D7_01_v3 84 Pf3D7_01_v3 110 Pf3D7_01_v3 111 Pf3D7_01_v3 129 Pf3D7_01_v3 146 Pf3D7_01_v3 147 Pf3D7_01_v3 152 Pf3D7_01_v3 168 Pf3D7_01_v3 169 Pf3D7_01_v3 175 Pf3D7_01_v3 195 Pf3D7_01_v3 196 Pf3D7_01_v3 199 Pf3D7_01_v3 204 Pf3D7_01_v3 213 Pf3D7_01_v3 222 Pf3D7_01_v3 223 Pf3D7_01_v3 227 Pf3D7_02_v3 90 Pf3D7_02_v3 100 Pf3D7_02_v3 111 Pf3D7_02_v3 129 Pf3D7_02_v3 146 Pf3D7_02_v3 147 Pf3D7_02_v3 152 Pf3D7_02_v3 168 Pf3D7_02_v3 169 Pf3D7_02_v3 175 Pf3D7_02_v3 195 Pf3D7_02_v3 196 Pf3D7_02_v3 199 Pf3D7_02_v3 204 Pf3D7_02_v3 213 Pf3D7_02_v3 222 Pf3D7_02_v3 223 Pf3D7_02_v3 227 Pf3D7_02_v3 235 Pf3D7_03_v3 1 Pf3D7_03_v3 2 Pf3D7_03_v3 33 Pf3D7_03_v3 36 Pf3D7_03_v3 57 Pf3D7_03_v3 61 Pf3D7_03_v3 72 Pf3D7_03_v3 73 Pf3D7_03_v3 74 Pf3D7_03_v3 84 Pf3D7_03_v3 110 Pf3D7_03_v3 111 Pf3D7_03_v3 129 Pf3D7_03_v3 146 Pf3D7_03_v3 147 Pf3D7_03_v3 152 Pf3D7_03_v3 168 Pf3D7_03_v3 169 Pf3D7_03_v3 175 Pf3D7_03_v3 195 Pf3D7_03_v3 196 Pf3D7_03_v3 199 Pf3D7_03_v3 204 Pf3D7_03_v3 213 Pf3D7_03_v3 222 Pf3D7_03_v3 223 Pf3D7_03_v3 227 Pf3D7_03_v3 235 bcftools-1.21/test/view.chrs.vcf000066400000000000000000000061711467060157400166560ustar00rootroot00000000000000##fileformat=VCFv4.1 ##contig= ##contig= ##contig= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA BBB Pf3D7_01_v3 1 . A T . . . GT . . Pf3D7_01_v3 2 . A G . . . GT . . Pf3D7_01_v3 33 . T A . . . GT . . Pf3D7_01_v3 36 . A G . . . GT . . Pf3D7_01_v3 57 . C T . . . GT . . Pf3D7_01_v3 61 . A T . . . GT . . Pf3D7_01_v3 72 . T C,A . . . GT . . Pf3D7_01_v3 73 . T A . . . GT . . Pf3D7_01_v3 74 . A T,C . . . GT . . Pf3D7_01_v3 84 . C T . . . GT . . Pf3D7_01_v3 110 . T A . . . GT . . Pf3D7_01_v3 111 . T A . . . GT . . Pf3D7_01_v3 129 . T A . . . GT . . Pf3D7_01_v3 146 . A C,T . . . GT . . Pf3D7_01_v3 147 . A C,T . . . GT . . Pf3D7_01_v3 152 . G T . . . GT . . Pf3D7_01_v3 168 . T A . . . GT . . Pf3D7_01_v3 169 . A G . . . GT . . Pf3D7_01_v3 175 . A T . . . GT . . Pf3D7_01_v3 195 . T A . . . GT . . Pf3D7_01_v3 196 . A C . . . GT . . Pf3D7_01_v3 199 . T C . . . GT . . Pf3D7_01_v3 204 . C T . . . GT . . Pf3D7_01_v3 213 . G A . . . GT . . Pf3D7_01_v3 222 . A G . . . GT . . Pf3D7_01_v3 223 . A G . . . GT . . Pf3D7_01_v3 227 . T A . . . GT . . Pf3D7_01_v3 235 . A G . . . GT . . Pf3D7_02_v3 1 . A T . . . GT . . Pf3D7_02_v3 2 . A G . . . GT . . Pf3D7_02_v3 33 . T A . . . GT . . Pf3D7_02_v3 36 . A G . . . GT . . Pf3D7_02_v3 57 . C T . . . GT . . Pf3D7_02_v3 61 . A T . . . GT . . Pf3D7_02_v3 72 . T C,A . . . GT . . Pf3D7_02_v3 73 . T A . . . GT . . Pf3D7_02_v3 74 . A T,C . . . GT . . Pf3D7_02_v3 90 . C T . . . GT . . Pf3D7_02_v3 100 . T A . . . GT . . Pf3D7_02_v3 111 . T A . . . GT . . Pf3D7_02_v3 129 . T A . . . GT . . Pf3D7_02_v3 146 . A C,T . . . GT . . Pf3D7_02_v3 147 . A C,T . . . GT . . Pf3D7_02_v3 152 . G T . . . GT . . Pf3D7_02_v3 168 . T A . . . GT . . Pf3D7_02_v3 169 . A G . . . GT . . Pf3D7_02_v3 175 . A T . . . GT . . Pf3D7_02_v3 195 . T A . . . GT . . Pf3D7_02_v3 196 . A C . . . GT . . Pf3D7_02_v3 199 . T C . . . GT . . Pf3D7_02_v3 204 . C T . . . GT . . Pf3D7_02_v3 213 . G A . . . GT . . Pf3D7_02_v3 222 . A G . . . GT . . Pf3D7_02_v3 223 . A G . . . GT . . Pf3D7_02_v3 227 . T A . . . GT . . Pf3D7_02_v3 235 . A G . . . GT . . Pf3D7_03_v3 1 . A T . . . GT . . Pf3D7_03_v3 2 . A G . . . GT . . Pf3D7_03_v3 33 . T A . . . GT . . Pf3D7_03_v3 36 . A G . . . GT . . Pf3D7_03_v3 57 . C T . . . GT . . Pf3D7_03_v3 61 . A T . . . GT . . Pf3D7_03_v3 72 . T C,A . . . GT . . Pf3D7_03_v3 73 . T A . . . GT . . Pf3D7_03_v3 74 . A T,C . . . GT . . Pf3D7_03_v3 84 . C T . . . GT . . Pf3D7_03_v3 110 . T A . . . GT . . Pf3D7_03_v3 111 . T A . . . GT . . Pf3D7_03_v3 129 . T A . . . GT . . Pf3D7_03_v3 146 . A C,T . . . GT . . Pf3D7_03_v3 147 . A C,T . . . GT . . Pf3D7_03_v3 152 . G T . . . GT . . Pf3D7_03_v3 168 . T A . . . GT . . Pf3D7_03_v3 169 . A G . . . GT . . Pf3D7_03_v3 175 . A T . . . GT . . Pf3D7_03_v3 195 . T A . . . GT . . Pf3D7_03_v3 196 . A C . . . GT . . Pf3D7_03_v3 199 . T C . . . GT . . Pf3D7_03_v3 204 . C T . . . GT . . Pf3D7_03_v3 213 . G A . . . GT . . Pf3D7_03_v3 222 . A G . . . GT . . Pf3D7_03_v3 223 . A G . . . GT . . Pf3D7_03_v3 227 . T A . . . GT . . Pf3D7_03_v3 235 . A G . . . GT . . bcftools-1.21/test/view.dropgenotypes.noheader.out000066400000000000000000000003171467060157400224320ustar00rootroot0000000000000020 14370 rs6054257 G A 29 PASS NS=3;DP=14 20 17330 . T A 3 PASS NS=3;DP=11 20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 20 1230237 . T . 47 PASS NS=3;DP=13 20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 bcftools-1.21/test/view.dropgenotypes.out000066400000000000000000000012031467060157400206410ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta ##contig= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO 20 14370 rs6054257 G A 29 PASS NS=3;DP=14 20 17330 . T A 3 PASS NS=3;DP=11 20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 20 1230237 . T . 47 PASS NS=3;DP=13 20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 bcftools-1.21/test/view.exclude.out000066400000000000000000000122571467060157400174030ustar00rootroot00000000000000##fileformat=VCFv4.1 ##FILTER= ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 11 2343543 . A . 999 PASS DP=100223;AN=4 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 11 5464562 . C T 999 PASS DP=0;AC=0;AN=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;AC=3;AN=4 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=4;AC=2 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=4;AC=2 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=4;AC=1,1 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=4;AC=2 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=2;AC=0 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=2;AC=0 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 bcftools-1.21/test/view.filter.1.out000066400000000000000000000005121467060157400173650ustar00rootroot000000000000001 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.10.out000066400000000000000000000072521467060157400174550ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF ./.:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.11.out000066400000000000000000000072521467060157400174560ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=2;AC=0,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR ./.:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.12.out000066400000000000000000000007301467060157400174510ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##FORMAT= ##FORMAT= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . G CA 238 PASS . GT:FILTER ./.:aaa 0/1:bbbb 1 3162007 . G CA 238 PASS . GT:FILTER 0/1:cc 0/1:d bcftools-1.21/test/view.filter.2.out000066400000000000000000000005121467060157400173660ustar00rootroot000000000000001 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.2.vcf000066400000000000000000000006441467060157400173430ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FORMAT= ##FORMAT= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . G CA 238 PASS . GT:FILTER 0/1:aaa 0/1:bbbb 1 3162007 . G CA 238 PASS . GT:FILTER 0/1:cc 0/1:d bcftools-1.21/test/view.filter.3.out000066400000000000000000000005121467060157400173670ustar00rootroot000000000000001 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.4.out000066400000000000000000000005121467060157400173700ustar00rootroot000000000000001 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.5.out000066400000000000000000000005121467060157400173710ustar00rootroot000000000000001 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 2:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.6.out000066400000000000000000000072521467060157400174020ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF ./.:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 .:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.7.out000066400000000000000000000072521467060157400174030ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF ./.:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 .:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.8.out000066400000000000000000000072521467060157400174040ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF ./.:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 .:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.9.out000066400000000000000000000072521467060157400174050ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 .:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 bcftools-1.21/test/view.filter.annovar.1.out000066400000000000000000000026121467060157400210330ustar00rootroot0000000000000020 1230237 . T G 47 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2:. 20 1230288 . T . 50 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2:. bcftools-1.21/test/view.filter.annovar.2.out000066400000000000000000000017061467060157400210370ustar00rootroot0000000000000016 50745926 rs2066844 C T 80 PASS NS=3;DP=14;AF=0.5;DB;H2;ANNOVAR_DATE=2015-06-17;Func.refGene=exonic;Gene.refGene=NOD2;GeneDetail.refGene=.;ExonicFunc.refGene=nonsynonymous_SNV;AAChange.refGene=NOD2:NM_001293557:exon3:c.C2023T:p.R675W,NOD2:NM_022162:exon4:c.C2104T:p.R702W;Func.ensGene=exonic;Gene.ensGene=ENSG00000167207;GeneDetail.ensGene=.;ExonicFunc.ensGene=nonsynonymous_SNV;AAChange.ensGene=ENSG00000167207:ENST00000300589:exon4:c.C2104T:p.R702W;esp6500si_ea=0.043488;esp6500si_all=0.031558;1000g2012apr_eur=0.05;1000g2012apr_all=0.02;snp138=rs2066844;LJB2_SIFT=0.010000;LJB2_PolyPhen2_HDIV=0.999;LJB2_PP2_HDIV_Pred=D;LJB2_PolyPhen2_HVAR=0.901;LJB2_PolyPhen2_HVAR_Pred=P;LJB2_LRT=0.993490;LJB2_LRT_Pred=N;LJB2_MutationTaster=0.291000;LJB2_MutationTaster_Pred=N;LJB_MutationAssessor=2.32;LJB_MutationAssessor_Pred=medium;LJB2_FATHMM=-0.5;LJB2_GERP++=3.66;LJB2_PhyloP=1.421000;LJB2_SiPhy=6.9139;ALLELE_END GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. bcftools-1.21/test/view.filter.annovar.3.out000066400000000000000000000017061467060157400210400ustar00rootroot0000000000000016 50745926 rs2066844 C T 80 PASS NS=3;DP=14;AF=0.5;DB;H2;ANNOVAR_DATE=2015-06-17;Func.refGene=exonic;Gene.refGene=NOD2;GeneDetail.refGene=.;ExonicFunc.refGene=nonsynonymous_SNV;AAChange.refGene=NOD2:NM_001293557:exon3:c.C2023T:p.R675W,NOD2:NM_022162:exon4:c.C2104T:p.R702W;Func.ensGene=exonic;Gene.ensGene=ENSG00000167207;GeneDetail.ensGene=.;ExonicFunc.ensGene=nonsynonymous_SNV;AAChange.ensGene=ENSG00000167207:ENST00000300589:exon4:c.C2104T:p.R702W;esp6500si_ea=0.043488;esp6500si_all=0.031558;1000g2012apr_eur=0.05;1000g2012apr_all=0.02;snp138=rs2066844;LJB2_SIFT=0.010000;LJB2_PolyPhen2_HDIV=0.999;LJB2_PP2_HDIV_Pred=D;LJB2_PolyPhen2_HVAR=0.901;LJB2_PolyPhen2_HVAR_Pred=P;LJB2_LRT=0.993490;LJB2_LRT_Pred=N;LJB2_MutationTaster=0.291000;LJB2_MutationTaster_Pred=N;LJB_MutationAssessor=2.32;LJB_MutationAssessor_Pred=medium;LJB2_FATHMM=-0.5;LJB2_GERP++=3.66;LJB2_PhyloP=1.421000;LJB2_SiPhy=6.9139;ALLELE_END GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. bcftools-1.21/test/view.filter.annovar.vcf000066400000000000000000000154201467060157400206440ustar00rootroot00000000000000##fileformat=VCFv4.0 ##fileDate=20090805 ##source=myImputationProgramV3.1 ##reference=1000GenomesPilot-NCBI36 ##phasing=partial ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 16 50745926 rs2066844 C T 80 PASS NS=3;DP=14;AF=0.5;DB;H2;ANNOVAR_DATE=2015-06-17;Func.refGene=exonic;Gene.refGene=NOD2;GeneDetail.refGene=.;ExonicFunc.refGene=nonsynonymous_SNV;AAChange.refGene=NOD2:NM_001293557:exon3:c.C2023T:p.R675W,NOD2:NM_022162:exon4:c.C2104T:p.R702W;Func.ensGene=exonic;Gene.ensGene=ENSG00000167207;GeneDetail.ensGene=.;ExonicFunc.ensGene=nonsynonymous_SNV;AAChange.ensGene=ENSG00000167207:ENST00000300589:exon4:c.C2104T:p.R702W;esp6500si_ea=0.043488;esp6500si_all=0.031558;1000g2012apr_eur=0.05;1000g2012apr_all=0.02;snp138=rs2066844;LJB2_SIFT=0.010000;LJB2_PolyPhen2_HDIV=0.999;LJB2_PP2_HDIV_Pred=D;LJB2_PolyPhen2_HVAR=0.901;LJB2_PolyPhen2_HVAR_Pred=P;LJB2_LRT=0.993490;LJB2_LRT_Pred=N;LJB2_MutationTaster=0.291000;LJB2_MutationTaster_Pred=N;LJB_MutationAssessor=2.32;LJB_MutationAssessor_Pred=medium;LJB2_FATHMM=-0.5;LJB2_GERP++=3.66;LJB2_PhyloP=1.421000;LJB2_SiPhy=6.9139;ALLELE_END GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. 20 1230237 . T G 47 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2 20 1230288 . T . 50 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2 bcftools-1.21/test/view.filter.vcf000066400000000000000000000071361467060157400172060ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e6,2e6,3e6;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e6,2e6;XAI=1111,2222;XAS=ABC,DEF;XGF=1e6,2e6,3e6,4e6,5e6,6e6;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:1e-1,2e-2,3e-3,4e-4,5e-5,6e-6:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 2:AAAAAA,BBB,C:1,2,3:1e-1,2e-2,3e-3:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 bcftools-1.21/test/view.minmaxac.1.out000066400000000000000000000001571467060157400177020ustar00rootroot0000000000000020 1234567 . A G,C,T 50 PASS NS=3;DP=9;AC=3,1,1;AN=8 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2:. 1/1:40:3:. 0/3:17:2:. bcftools-1.21/test/view.minmaxac.2.out000066400000000000000000000001571467060157400177030ustar00rootroot0000000000000020 1234568 . A G,C,T 50 PASS NS=3;DP=9;AC=2,2,2;AN=8 GT:GQ:DP:TS 0/1:35:4:A,. 2/2:17:2:. 3/3:40:3:. 0/1:17:2:. bcftools-1.21/test/view.minmaxac.vcf000066400000000000000000000016641467060157400175160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta ##contig= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 20 1234567 . A G,C,T 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2 1/1:40:3 0/3:17:2 20 1234568 . A G,C,T 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 2/2:17:2 3/3:40:3 0/1:17:2 bcftools-1.21/test/view.omitgenotypes.out000066400000000000000000000023571467060157400206600ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta ##contig= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 20 14370 rs6054257 G A 29 PASS NS=3;DP=14 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. 20 17330 . T A 3 PASS NS=3;DP=11 GT:GQ:DP:HQ ./.:.:.:.,. ./.:.:.:.,. ./.:.:.:.,. 20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 GT:GQ:DP:HQ:TS ./.:.:.:.:. ./.:.:.:.:. ./.:.:.:.:. 20 1230237 . T . 47 PASS NS=3;DP=13 GT:GQ:DP:HQ:TS .:.:.:.:. .:.:.:.:. .:.:.:.:. 20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2:. 1/1:40:3:. bcftools-1.21/test/view.omitgenotypes.vcf000066400000000000000000000022071467060157400206210ustar00rootroot00000000000000##fileformat=VCFv4.2 ##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta ##contig= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 20 14370 rs6054257 G A 29 PASS NS=3;DP=14 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. 20 17330 . T A 3 PASS NS=3;DP=11 GT:GQ:DP:HQ ./.:.:.:.,. ./.:.:.:.,. ./.:.:.:.,. 20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 GT:GQ:DP:HQ:TS ./. ./. ./. 20 1230237 . T . 47 PASS NS=3;DP=13 GT:GQ:DP:HQ:TS . . . 20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2 1/1:40:3 bcftools-1.21/test/view.sites.1.out000066400000000000000000000003441467060157400172320ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10001 . G C 40 . . 1 10002 . T A 50 . . 1 10003 . A G 60 . . 1 10004 . A T 70 . . bcftools-1.21/test/view.sites.txt000066400000000000000000000000601467060157400170760ustar00rootroot000000000000001 10001 G A 1 10002 T A 1 10003 G C 1 10004 A C bcftools-1.21/test/view.sites.txt.gz000066400000000000000000000001261467060157400175200ustar00rootroot00000000000000‹ÿBC93ä44000ätçtä2³8Càlc ¸3”mÂédd„0‹ÿBCbcftools-1.21/test/view.sites.txt.gz.tbi000066400000000000000000000001401467060157400202710ustar00rootroot00000000000000‹ÿBCC qòddd€ÍÅÊP1ÛLz AT €˜ôšQ….΀ 0ÑÕS~‹ÿBCbcftools-1.21/test/view.sites.vcf000066400000000000000000000003441467060157400170420ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 10001 . G C 40 . . 1 10002 . T A 50 . . 1 10003 . A G 60 . . 1 10004 . A T 70 . . bcftools-1.21/test/view.vcf000066400000000000000000000125521467060157400157200ustar00rootroot00000000000000##fileformat=VCFv4.1 ##reference=file:///seq/references/1000Genomes-NCBI37.fasta ##contig= ##contig= ##contig= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##FILTER= ##FILTER= ##FILTER= ##FILTER= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0:193:99 0/0:0:211:99 0/0:0:182:99 11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. 20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 . Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 . bcftools-1.21/test/view.vectors.2.vcf000066400000000000000000000040121467060157400175340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 10 . A C,T 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.,.;IRS=.,.,.;IGS=.,.,.,.,.,. GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.,.:.,.,.:.,.,.,.,.,. 0/0:.:.:.:.:.:.:.,.:.,.,.:.,.,.,.,.,. 1 20 . A T,G 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.,.;IRS=.,.,.;IGS=.,.,.,.,.,. GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1 0/0:. 1 30 . G A,C 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.;IGS=. GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.:.:. 0/0:.:.:.:.:.:.:.:.:. bcftools-1.21/test/view.vectors.A.out000066400000000000000000000105341467060157400176120ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 3162006 . GAA G 238 PASS DP=19;AN=2;AC=1;XRF=1e+06,2e+06;XRI=1111,2222;XRS=ABC,DEF;XAF=1e+06;XAI=1111;XAS=ABC;XGF=1e+06,2e+06,3e+06;XGI=11,22,33;XGS=ABC,DEF,GHI;TXT=ABC,DEF,GHI GT:GQ:DP 0/1:589:19 1 3162007 . TAGGG CAGGG 238 PASS AO=52101;CIGAR=1X4M;AC=1;AN=2 GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC:1,2,3:0.1,0.02,0.003:AAA:1:0.1:A,BB:1,2:0.1,0.02 1 3162008 . TAGGG CAGGG 238 PASS IA8=10,.;IA16=1000,.;IA32=100000,.;IAF=0.003,.;CIGAR=1X4M;AC=1;AN=2 GT:F8:F16:F32:FF 0/1:10:1000:100000:0.003 1 3162009 . TAGGG CAGGG 238 PASS IA8=.;IA16=.;IA32=.;IAF=.;CIGAR=1X4M;AC=1;AN=2 GT:F8:F16:F32:FF 0/1:10:1000:100000:0.003 1 3162010 . TAGGG CAGGG 238 PASS I8=.;I16=.;I32=.;IF=.;CIGAR=1X4M;AC=1;AN=2 GT:F8:F16:F32:FF 0/1:10:1000:100000:0.003 bcftools-1.21/test/view.vectors.B.out000066400000000000000000000104421467060157400176110ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B 1 3162006 . GAA GA 238 PASS DP=19;AN=2;AC=1;XRF=1e+06,3e+06;XRI=1111,3333;XRS=ABC,GHI;XAF=2e+06;XAI=2222;XAS=DEF;XGF=1e+06,4e+06,6e+06;XGI=11,44,66;XGS=ABC,JKL,PQR;TXT=ABC,DEF,GHI GT:GQ:DP 0/1:1:1 1 3162007 . TAGGG CAGGT 238 PASS AO=113;CIGAR=1X3M1X;AC=1;AN=1 GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 1:AAAAAA,C:1,3:0.1,0.003:B:2:0.02:A,CCC:1,3:0.1,0.003 1 3162008 . TAGGG CAGGT 238 PASS IA8=10,.;IA16=1000,.;IA32=100000,.;IAF=0.003,.;CIGAR=1X3M1X;AC=1;AN=1 GT:F8:F16:F32:FF 1:.:.:.:. 1 3162009 . TAGGG CAGGT 238 PASS IA8=.;IA16=.;IA32=.;IAF=.;CIGAR=1X3M1X;AC=1;AN=1 GT:F8:F16:F32:FF 1:.:.:.:. 1 3162010 . TAGGG CAGGT 238 PASS I8=.;I16=.;I32=.;IF=.;CIGAR=1X3M1X;AC=1;AN=1 GT:F8:F16:F32:FF 1:.:.:.:. bcftools-1.21/test/view.vectors.C.out000066400000000000000000000042541467060157400176160ustar00rootroot00000000000000##fileformat=VCFv4.2 ##FILTER= ##contig= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A 1 10 . A C 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.,.;IGS=.,.,.;AC=1;AN=2 GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.:.,.:.,.,. 1 20 . A T 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.,.;IGS=.,.,.;AC=1;AN=2 GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.:.:. 1 30 . G A 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.;IGS=.;AC=1;AN=2 GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS 0/1:.:.:.:.:.:.:.:. bcftools-1.21/test/view.vectors.vcf000066400000000000000000000110321467060157400173740ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FILTER= ##contig= ##contig= ##contig= ##contig= ##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e6,2e6,3e6;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e6,2e6;XAI=1111,2222;XAS=ABC,DEF;XGF=1e6,2e6,3e6,4e6,5e6,6e6;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP 0/1:589:19 0/2:1:1 1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:1e-1,2e-2,3e-3,4e-4,5e-5,6e-6:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 2:AAAAAA,BBB,C:1,2,3:1e-1,2e-2,3e-3:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 1 3162008 . TAGGG CAGGG,CAGGT 238 PASS IA8=10,.;IA16=1000,.;IA32=100000,.;IAF=3e-3,.;CIGAR=1X4M,1X3M1X GT:F8:F16:F32:FF 0/1:10:1000:100000:3e-3 2:.:.:.:. 1 3162009 . TAGGG CAGGG,CAGGT 238 PASS IA8=.;IA16=.;IA32=.;IAF=.;CIGAR=1X4M,1X3M1X GT:F8:F16:F32:FF 0/1:10:1000:100000:3e-3 2:.:.:.:. 1 3162010 . TAGGG CAGGG,CAGGT 238 PASS I8=.;I16=.;I32=.;IF=.;CIGAR=1X4M,1X3M1X GT:F8:F16:F32:FF 0/1:10:1000:100000:3e-3 2:.:.:.:. bcftools-1.21/test/view64bit.1.out000066400000000000000000000002101467060157400167450ustar00rootroot00000000000000chr1 1 . G C . . MPOS=.;XPOS=.,.,.;NALOD=-0.8279;NLOD=15.45;POPAF=6 chr1 2 . G C . . MPOS=.;XPOS=.,.,.;NALOD=-0.8279;NLOD=15.45;POPAF=6 bcftools-1.21/test/view64bit.1.vcf000066400000000000000000000011471467060157400167260ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO chr1 1 . G C . . MPOS=-2147483641;XPOS=-2147483641,-2147483641,-2147483641;NALOD=-8.279e-01;NLOD=15.45;POPAF=6.00 chr1 2 . G C . . MPOS=-2147483648;XPOS=-2147483648,-2147483648,-2147483648;NALOD=-8.279e-01;NLOD=15.45;POPAF=6.00 bcftools-1.21/test/view64bit.2.out000066400000000000000000000000651467060157400167560ustar00rootroot00000000000000chr1 1 . G C . . MPOS=.;XPOS=.,.,. MPOS:XPOS .:.,.,. bcftools-1.21/test/view64bit.2.vcf000066400000000000000000000007431467060157400167300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . G C . . MPOS=42949672950;XPOS=42949672950,42949672950,42949672950 MPOS:XPOS 42949672950:42949672950,42949672950,42949672950 bcftools-1.21/test/view64bit.3.out000066400000000000000000000000771467060157400167620ustar00rootroot00000000000000chr1 42949672950 . G C . . MPOS=.;XPOS=.,.,. MPOS:XPOS .:.,.,. bcftools-1.21/test/view64bit.3.vcf000066400000000000000000000007551467060157400167340ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 42949672950 . G C . . MPOS=42949672950;XPOS=42949672950,42949672950,42949672950 MPOS:XPOS 42949672950:42949672950,42949672950,42949672950 bcftools-1.21/test/view64bit.4.out000066400000000000000000000000651467060157400167600ustar00rootroot00000000000000chr1 1 . G C . . MPOS=.;XPOS=.,.,. MPOS:XPOS .:.,.,. bcftools-1.21/test/view64bit.4.vcf000066400000000000000000000006231467060157400167270ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##FORMAT= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE chr1 1 . G C . . MPOS=.;XPOS=.,.,. MPOS:XPOS .:.,.,. bcftools-1.21/test/view64bit.5.out000066400000000000000000000003651467060157400167640ustar00rootroot00000000000000chr1 1 . G C . . END=42949672,1,.;MPOS=100000000 XX 1,-2147483640,.,.,.,2147483647,. chr1 1 . G C . . END=-2147483640 XX -2147483640 chr1 1 . G C . . END=. XX . chr1 1 . G C . . END=. XX . chr1 1 . G C . . END=. XX . chr1 1 . G C . . END=. XX . bcftools-1.21/test/view64bit.5.vcf000066400000000000000000000012171467060157400167300ustar00rootroot00000000000000##fileformat=VCFv4.2 ##INFO= ##INFO= ##FORMAT= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 chr1 1 . G C . . END=42949672,1,5000000000;MPOS=100000000 XX 1,-2147483640,-2147483641,-2147483647,-2147483648,2147483647,2147483648 chr1 1 . G C . . END=-2147483640 XX -2147483640 chr1 1 . G C . . END=-2147483641 XX -2147483641 chr1 1 . G C . . END=-2147483647 XX -2147483647 chr1 1 . G C . . END=-2147483648 XX -2147483648 chr1 1 . G C . . END=-2147483649 XX -2147483649 bcftools-1.21/test/weird-chr-names.1.out000066400000000000000000000003311467060157400201130ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T . . . 1 2 . C T . . . bcftools-1.21/test/weird-chr-names.2.out000066400000000000000000000003111467060157400201120ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T . . . bcftools-1.21/test/weird-chr-names.3.out000066400000000000000000000003351467060157400201210ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1:1 1 . C T . . . 1:1 2 . C T . . . bcftools-1.21/test/weird-chr-names.4.out000066400000000000000000000003131467060157400201160ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1:1 1 . C T . . . bcftools-1.21/test/weird-chr-names.5.out000066400000000000000000000003411467060157400201200ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1:1-1 1 . C T . . . 1:1-1 2 . C T . . . bcftools-1.21/test/weird-chr-names.6.out000066400000000000000000000003151467060157400201220ustar00rootroot00000000000000##fileformat=VCFv4.3 ##FILTER= ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1:1-1 1 . C T . . . bcftools-1.21/test/weird-chr-names.vcf000066400000000000000000000003611467060157400177260ustar00rootroot00000000000000##fileformat=VCFv4.3 ##reference=ref.fa ##contig= ##contig= ##contig= #CHROM POS ID REF ALT QUAL FILTER INFO 1 1 . C T . . . 1 2 . C T . . . 1:1 1 . C T . . . 1:1 2 . C T . . . 1:1-1 1 . C T . . . 1:1-1 2 . C T . . . bcftools-1.21/tsv2vcf.c000066400000000000000000000075261467060157400150350ustar00rootroot00000000000000/* tsv2vcf.c -- convert from whitespace-separated fields to VCF Copyright (C) 2014-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include "tsv2vcf.h" tsv_t *tsv_init(const char *str) { tsv_t *tsv = (tsv_t *) calloc(1,sizeof(tsv_t)); kstring_t tmp = {0,0,0}; const char *ss = str, *se = ss; tsv->ncols = 0; while ( *ss ) { if ( *se && *se!=',' ) { se++; continue; } tsv->ncols++; tsv->cols = (tsv_col_t*) realloc(tsv->cols,sizeof(tsv_col_t)*tsv->ncols); tsv->cols[tsv->ncols-1].name = NULL; tsv->cols[tsv->ncols-1].setter = NULL; tmp.l = 0; kputsn(ss, se-ss, &tmp); if ( strcasecmp("-",tmp.s) ) tsv->cols[tsv->ncols-1].name = strdup(tmp.s); if ( !*se ) break; ss = ++se; } free(tmp.s); return tsv; } void tsv_destroy(tsv_t *tsv) { int i; for (i=0; incols; i++) free(tsv->cols[i].name); free(tsv->cols); free(tsv); } int tsv_register(tsv_t *tsv, const char *id, tsv_setter_t setter, void *usr) { int i; for (i=0; incols; i++) { if ( !tsv->cols[i].name || strcasecmp(tsv->cols[i].name,id) ) continue; tsv->cols[i].setter = setter; tsv->cols[i].usr = usr; return 0; } return -1; } int tsv_parse(tsv_t *tsv, bcf1_t *rec, char *str) { int status = 0; tsv->icol = 0; tsv->ss = tsv->se = str; while ( *tsv->ss && tsv->icol < tsv->ncols ) { while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; if ( tsv->cols[tsv->icol].setter ) { int ret = tsv->cols[tsv->icol].setter(tsv,rec,tsv->cols[tsv->icol].usr); if ( ret<0 ) return -1; status++; } while ( *tsv->se && isspace(*tsv->se) ) tsv->se++; tsv->ss = tsv->se; tsv->icol++; } return status ? 0 : -1; } int tsv_setter_chrom(tsv_t *tsv, bcf1_t *rec, void *usr) { char tmp = *tsv->se; *tsv->se = 0; rec->rid = bcf_hdr_name2id((bcf_hdr_t*)usr, tsv->ss); *tsv->se = tmp; return rec->rid==-1 ? -1 : 0; } int tsv_setter_pos(tsv_t *tsv, bcf1_t *rec, void *usr) { char *endptr; rec->pos = strtol(tsv->ss, &endptr, 10) - 1; if ( tsv->ss==endptr ) return -1; return 0; } int tsv_setter_id(tsv_t *tsv, bcf1_t *rec, void *usr) { char tmp = *tsv->se; *tsv->se = 0; bcf_update_id((bcf_hdr_t*)usr, rec, tsv->ss); *tsv->se = tmp; return 0; } int tsv_setter_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr) { bcf_hdr_t *hdr = (bcf_hdr_t*)usr; char *sb = tsv->ss; while ( *sb && !isspace(*sb) ) sb++; if ( !*sb ) return -1; char tmp = *sb; *sb = ','; bcf_update_alleles_str(hdr, rec, tsv->ss); *sb = tmp; return 0; } bcftools-1.21/tsv2vcf.h000066400000000000000000000052421467060157400150330ustar00rootroot00000000000000/* tsv2vcf.h -- convert from whitespace-separated fields to VCF Copyright (C) 2014-2021 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __TSV2VCF_H__ #define __TSV2VCF_H__ #include typedef struct _tsv_t tsv_t; typedef int (*tsv_setter_t)(tsv_t *, bcf1_t *, void *); typedef struct { char *name; tsv_setter_t setter; void *usr; } tsv_col_t; struct _tsv_t { int ncols, icol; tsv_col_t *cols; char *se, *ss; }; tsv_t *tsv_init(const char *str); void tsv_destroy(tsv_t *tsv); int tsv_register(tsv_t *tsv, const char *id, tsv_setter_t setter, void *usr); /** * tsv_parse() - parse tsv line and fill VCF record * Returns 0 on success or -1 on parse error */ int tsv_parse(tsv_t *tsv, bcf1_t *rec, char *str); /** * tstv_next() - position ss,se to next field; first pass with ss=se=str * Returns 0 on success, or -1 if no more fields */ static inline int tsv_next(tsv_t *tsv) { if ( !*tsv->se ) return -1; if ( tsv->ss==tsv->se ) { while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; return 0; } while ( *tsv->se && isspace(*tsv->se) ) tsv->se++; tsv->ss = tsv->se; while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; return 0; } /** * The setters return 0 on success or negative value if the line is to be skipped. */ int tsv_setter_chrom(tsv_t *tsv, bcf1_t *rec, void *usr); int tsv_setter_pos(tsv_t *tsv, bcf1_t *rec, void *usr); int tsv_setter_id(tsv_t *tsv, bcf1_t *rec, void *usr); int tsv_setter_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr); // usr must point to bcf_hdr_t #endif bcftools-1.21/utlist.h000066400000000000000000001552521467060157400147710ustar00rootroot00000000000000/* Copyright (c) 2007-2014, Troy D. Hanson http://troydhanson.github.com/uthash/ All rights reserved. Redistribution and use in source and binary forms, with or without modification, are permitted provided that the following conditions are met: * Redistributions of source code must retain the above copyright notice, this list of conditions and the following disclaimer. THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. */ #ifndef UTLIST_H #define UTLIST_H #define UTLIST_VERSION 1.9.9 #include /* * This file contains macros to manipulate singly and doubly-linked lists. * * 1. LL_ macros: singly-linked lists. * 2. DL_ macros: doubly-linked lists. * 3. CDL_ macros: circular doubly-linked lists. * * To use singly-linked lists, your structure must have a "next" pointer. * To use doubly-linked lists, your structure must "prev" and "next" pointers. * Either way, the pointer to the head of the list must be initialized to NULL. * * ----------------.EXAMPLE ------------------------- * struct item { * int id; * struct item *prev, *next; * } * * struct item *list = NULL: * * int main() { * struct item *item; * ... allocate and populate item ... * DL_APPEND(list, item); * } * -------------------------------------------------- * * For doubly-linked lists, the append and delete macros are O(1) * For singly-linked lists, append and delete are O(n) but prepend is O(1) * The sort macro is O(n log(n)) for all types of single/double/circular lists. */ /* These macros use decltype or the earlier __typeof GNU extension. As decltype is only available in newer compilers (VS2010 or gcc 4.3+ when compiling c++ code), this code uses whatever method is needed or, for VS2008 where neither is available, uses casting workarounds. */ #ifdef _MSC_VER /* MS compiler */ #if _MSC_VER >= 1600 && defined(__cplusplus) /* VS2010 or newer in C++ mode */ #define LDECLTYPE(x) decltype(x) #else /* VS2008 or older (or VS2010 in C mode) */ #define NO_DECLTYPE #define LDECLTYPE(x) char* #endif #elif defined(__ICCARM__) #define NO_DECLTYPE #define LDECLTYPE(x) char* #else /* GNU, Sun and other compilers */ #define LDECLTYPE(x) __typeof(x) #endif /* for VS2008 we use some workarounds to get around the lack of decltype, * namely, we always reassign our tmp variable to the list head if we need * to dereference its prev/next pointers, and save/restore the real head.*/ #ifdef NO_DECLTYPE #define _SV(elt,list) _tmp = (char*)(list); {char **_alias = (char**)&(list); *_alias = (elt); } #define _NEXT(elt,list,next) ((char*)((list)->next)) #define _NEXTASGN(elt,list,to,next) { char **_alias = (char**)&((list)->next); *_alias=(char*)(to); } /* #define _PREV(elt,list,prev) ((char*)((list)->prev)) */ #define _PREVASGN(elt,list,to,prev) { char **_alias = (char**)&((list)->prev); *_alias=(char*)(to); } #define _RS(list) { char **_alias = (char**)&(list); *_alias=_tmp; } #define _CASTASGN(a,b) { char **_alias = (char**)&(a); *_alias=(char*)(b); } #else #define _SV(elt,list) #define _NEXT(elt,list,next) ((elt)->next) #define _NEXTASGN(elt,list,to,next) ((elt)->next)=(to) /* #define _PREV(elt,list,prev) ((elt)->prev) */ #define _PREVASGN(elt,list,to,prev) ((elt)->prev)=(to) #define _RS(list) #define _CASTASGN(a,b) (a)=(b) #endif /****************************************************************************** * The sort macro is an adaptation of Simon Tatham's O(n log(n)) mergesort * * Unwieldy variable names used here to avoid shadowing passed-in variables. * *****************************************************************************/ #define LL_SORT(list, cmp) \ LL_SORT2(list, cmp, next) #define LL_SORT2(list, cmp, next) \ do { \ LDECLTYPE(list) _ls_p; \ LDECLTYPE(list) _ls_q; \ LDECLTYPE(list) _ls_e; \ LDECLTYPE(list) _ls_tail; \ int _ls_insize, _ls_nmerges, _ls_psize, _ls_qsize, _ls_i, _ls_looping; \ if (list) { \ _ls_insize = 1; \ _ls_looping = 1; \ while (_ls_looping) { \ _CASTASGN(_ls_p,list); \ list = NULL; \ _ls_tail = NULL; \ _ls_nmerges = 0; \ while (_ls_p) { \ _ls_nmerges++; \ _ls_q = _ls_p; \ _ls_psize = 0; \ for (_ls_i = 0; _ls_i < _ls_insize; _ls_i++) { \ _ls_psize++; \ _SV(_ls_q,list); _ls_q = _NEXT(_ls_q,list,next); _RS(list); \ if (!_ls_q) break; \ } \ _ls_qsize = _ls_insize; \ while (_ls_psize > 0 || (_ls_qsize > 0 && _ls_q)) { \ if (_ls_psize == 0) { \ _ls_e = _ls_q; _SV(_ls_q,list); _ls_q = \ _NEXT(_ls_q,list,next); _RS(list); _ls_qsize--; \ } else if (_ls_qsize == 0 || !_ls_q) { \ _ls_e = _ls_p; _SV(_ls_p,list); _ls_p = \ _NEXT(_ls_p,list,next); _RS(list); _ls_psize--; \ } else if (cmp(_ls_p,_ls_q) <= 0) { \ _ls_e = _ls_p; _SV(_ls_p,list); _ls_p = \ _NEXT(_ls_p,list,next); _RS(list); _ls_psize--; \ } else { \ _ls_e = _ls_q; _SV(_ls_q,list); _ls_q = \ _NEXT(_ls_q,list,next); _RS(list); _ls_qsize--; \ } \ if (_ls_tail) { \ _SV(_ls_tail,list); _NEXTASGN(_ls_tail,list,_ls_e,next); _RS(list); \ } else { \ _CASTASGN(list,_ls_e); \ } \ _ls_tail = _ls_e; \ } \ _ls_p = _ls_q; \ } \ if (_ls_tail) { \ _SV(_ls_tail,list); _NEXTASGN(_ls_tail,list,NULL,next); _RS(list); \ } \ if (_ls_nmerges <= 1) { \ _ls_looping=0; \ } \ _ls_insize *= 2; \ } \ } \ } while (0) #define DL_SORT(list, cmp) \ DL_SORT2(list, cmp, prev, next) #define DL_SORT2(list, cmp, prev, next) \ do { \ LDECLTYPE(list) _ls_p; \ LDECLTYPE(list) _ls_q; \ LDECLTYPE(list) _ls_e; \ LDECLTYPE(list) _ls_tail; \ int _ls_insize, _ls_nmerges, _ls_psize, _ls_qsize, _ls_i, _ls_looping; \ if (list) { \ _ls_insize = 1; \ _ls_looping = 1; \ while (_ls_looping) { \ _CASTASGN(_ls_p,list); \ list = NULL; \ _ls_tail = NULL; \ _ls_nmerges = 0; \ while (_ls_p) { \ _ls_nmerges++; \ _ls_q = _ls_p; \ _ls_psize = 0; \ for (_ls_i = 0; _ls_i < _ls_insize; _ls_i++) { \ _ls_psize++; \ _SV(_ls_q,list); _ls_q = _NEXT(_ls_q,list,next); _RS(list); \ if (!_ls_q) break; \ } \ _ls_qsize = _ls_insize; \ while (_ls_psize > 0 || (_ls_qsize > 0 && _ls_q)) { \ if (_ls_psize == 0) { \ _ls_e = _ls_q; _SV(_ls_q,list); _ls_q = \ _NEXT(_ls_q,list,next); _RS(list); _ls_qsize--; \ } else if (_ls_qsize == 0 || !_ls_q) { \ _ls_e = _ls_p; _SV(_ls_p,list); _ls_p = \ _NEXT(_ls_p,list,next); _RS(list); _ls_psize--; \ } else if (cmp(_ls_p,_ls_q) <= 0) { \ _ls_e = _ls_p; _SV(_ls_p,list); _ls_p = \ _NEXT(_ls_p,list,next); _RS(list); _ls_psize--; \ } else { \ _ls_e = _ls_q; _SV(_ls_q,list); _ls_q = \ _NEXT(_ls_q,list,next); _RS(list); _ls_qsize--; \ } \ if (_ls_tail) { \ _SV(_ls_tail,list); _NEXTASGN(_ls_tail,list,_ls_e,next); _RS(list); \ } else { \ _CASTASGN(list,_ls_e); \ } \ _SV(_ls_e,list); _PREVASGN(_ls_e,list,_ls_tail,prev); _RS(list); \ _ls_tail = _ls_e; \ } \ _ls_p = _ls_q; \ } \ _CASTASGN(list->prev, _ls_tail); \ _SV(_ls_tail,list); _NEXTASGN(_ls_tail,list,NULL,next); _RS(list); \ if (_ls_nmerges <= 1) { \ _ls_looping=0; \ } \ _ls_insize *= 2; \ } \ } \ } while (0) #define DL_HEAD(list) (list) #define DL_TAIL(list) ((list) ? (list)->prev : NULL) #define CDL_SORT(list, cmp) \ CDL_SORT2(list, cmp, prev, next) #define CDL_SORT2(list, cmp, prev, next) \ do { \ LDECLTYPE(list) _ls_p; \ LDECLTYPE(list) _ls_q; \ LDECLTYPE(list) _ls_e; \ LDECLTYPE(list) _ls_tail; \ LDECLTYPE(list) _ls_oldhead; \ LDECLTYPE(list) _tmp; \ int _ls_insize, _ls_nmerges, _ls_psize, _ls_qsize, _ls_i, _ls_looping; \ if (list) { \ _ls_insize = 1; \ _ls_looping = 1; \ while (_ls_looping) { \ _CASTASGN(_ls_p,list); \ _CASTASGN(_ls_oldhead,list); \ list = NULL; \ _ls_tail = NULL; \ _ls_nmerges = 0; \ while (_ls_p) { \ _ls_nmerges++; \ _ls_q = _ls_p; \ _ls_psize = 0; \ for (_ls_i = 0; _ls_i < _ls_insize; _ls_i++) { \ _ls_psize++; \ _SV(_ls_q,list); \ if (_NEXT(_ls_q,list,next) == _ls_oldhead) { \ _ls_q = NULL; \ } else { \ _ls_q = _NEXT(_ls_q,list,next); \ } \ _RS(list); \ if (!_ls_q) break; \ } \ _ls_qsize = _ls_insize; \ while (_ls_psize > 0 || (_ls_qsize > 0 && _ls_q)) { \ if (_ls_psize == 0) { \ _ls_e = _ls_q; _SV(_ls_q,list); _ls_q = \ _NEXT(_ls_q,list,next); _RS(list); _ls_qsize--; \ if (_ls_q == _ls_oldhead) { _ls_q = NULL; } \ } else if (_ls_qsize == 0 || !_ls_q) { \ _ls_e = _ls_p; _SV(_ls_p,list); _ls_p = \ _NEXT(_ls_p,list,next); _RS(list); _ls_psize--; \ if (_ls_p == _ls_oldhead) { _ls_p = NULL; } \ } else if (cmp(_ls_p,_ls_q) <= 0) { \ _ls_e = _ls_p; _SV(_ls_p,list); _ls_p = \ _NEXT(_ls_p,list,next); _RS(list); _ls_psize--; \ if (_ls_p == _ls_oldhead) { _ls_p = NULL; } \ } else { \ _ls_e = _ls_q; _SV(_ls_q,list); _ls_q = \ _NEXT(_ls_q,list,next); _RS(list); _ls_qsize--; \ if (_ls_q == _ls_oldhead) { _ls_q = NULL; } \ } \ if (_ls_tail) { \ _SV(_ls_tail,list); _NEXTASGN(_ls_tail,list,_ls_e,next); _RS(list); \ } else { \ _CASTASGN(list,_ls_e); \ } \ _SV(_ls_e,list); _PREVASGN(_ls_e,list,_ls_tail,prev); _RS(list); \ _ls_tail = _ls_e; \ } \ _ls_p = _ls_q; \ } \ _CASTASGN(list->prev,_ls_tail); \ _CASTASGN(_tmp,list); \ _SV(_ls_tail,list); _NEXTASGN(_ls_tail,list,_tmp,next); _RS(list); \ if (_ls_nmerges <= 1) { \ _ls_looping=0; \ } \ _ls_insize *= 2; \ } \ } \ } while (0) /****************************************************************************** * singly linked list macros (non-circular) * *****************************************************************************/ #define LL_PREPEND(head,add) \ LL_PREPEND2(head,add,next) #define LL_PREPEND2(head,add,next) \ do { \ (add)->next = head; \ head = add; \ } while (0) #define LL_CONCAT(head1,head2) \ LL_CONCAT2(head1,head2,next) #define LL_CONCAT2(head1,head2,next) \ do { \ LDECLTYPE(head1) _tmp; \ if (head1) { \ _tmp = head1; \ while (_tmp->next) { _tmp = _tmp->next; } \ _tmp->next=(head2); \ } else { \ (head1)=(head2); \ } \ } while (0) #define LL_APPEND(head,add) \ LL_APPEND2(head,add,next) #define LL_APPEND2(head,add,next) \ do { \ LDECLTYPE(head) _tmp; \ (add)->next=NULL; \ if (head) { \ _tmp = head; \ while (_tmp->next) { _tmp = _tmp->next; } \ _tmp->next=(add); \ } else { \ (head)=(add); \ } \ } while (0) #define LL_DELETE(head,del) \ LL_DELETE2(head,del,next) #define LL_DELETE2(head,del,next) \ do { \ LDECLTYPE(head) _tmp; \ if ((head) == (del)) { \ (head)=(head)->next; \ } else { \ _tmp = head; \ while (_tmp->next && (_tmp->next != (del))) { \ _tmp = _tmp->next; \ } \ if (_tmp->next) { \ _tmp->next = ((del)->next); \ } \ } \ } while (0) /* Here are VS2008 replacements for LL_APPEND and LL_DELETE */ #define LL_APPEND_VS2008(head,add) \ LL_APPEND2_VS2008(head,add,next) #define LL_APPEND2_VS2008(head,add,next) \ do { \ if (head) { \ (add)->next = head; /* use add->next as a temp variable */ \ while ((add)->next->next) { (add)->next = (add)->next->next; } \ (add)->next->next=(add); \ } else { \ (head)=(add); \ } \ (add)->next=NULL; \ } while (0) #define LL_DELETE_VS2008(head,del) \ LL_DELETE2_VS2008(head,del,next) #define LL_DELETE2_VS2008(head,del,next) \ do { \ if ((head) == (del)) { \ (head)=(head)->next; \ } else { \ char *_tmp = (char*)(head); \ while ((head)->next && ((head)->next != (del))) { \ head = (head)->next; \ } \ if ((head)->next) { \ (head)->next = ((del)->next); \ } \ { \ char **_head_alias = (char**)&(head); \ *_head_alias = _tmp; \ } \ } \ } while (0) #ifdef NO_DECLTYPE #undef LL_APPEND #define LL_APPEND LL_APPEND_VS2008 #undef LL_DELETE #define LL_DELETE LL_DELETE_VS2008 #undef LL_DELETE2 #define LL_DELETE2 LL_DELETE2_VS2008 #undef LL_APPEND2 #define LL_APPEND2 LL_APPEND2_VS2008 #undef LL_CONCAT /* no LL_CONCAT_VS2008 */ #undef DL_CONCAT /* no DL_CONCAT_VS2008 */ #endif /* end VS2008 replacements */ #define LL_COUNT(head,el,counter) \ LL_COUNT2(head,el,counter,next) \ #define LL_COUNT2(head,el,counter,next) \ { \ counter = 0; \ LL_FOREACH2(head,el,next){ ++counter; } \ } #define LL_FOREACH(head,el) \ LL_FOREACH2(head,el,next) #define LL_FOREACH2(head,el,next) \ for(el=head;el;el=(el)->next) #define LL_FOREACH_SAFE(head,el,tmp) \ LL_FOREACH_SAFE2(head,el,tmp,next) #define LL_FOREACH_SAFE2(head,el,tmp,next) \ for((el)=(head);(el) && (tmp = (el)->next, 1); (el) = tmp) #define LL_SEARCH_SCALAR(head,out,field,val) \ LL_SEARCH_SCALAR2(head,out,field,val,next) #define LL_SEARCH_SCALAR2(head,out,field,val,next) \ do { \ LL_FOREACH2(head,out,next) { \ if ((out)->field == (val)) break; \ } \ } while(0) #define LL_SEARCH(head,out,elt,cmp) \ LL_SEARCH2(head,out,elt,cmp,next) #define LL_SEARCH2(head,out,elt,cmp,next) \ do { \ LL_FOREACH2(head,out,next) { \ if ((cmp(out,elt))==0) break; \ } \ } while(0) #define LL_REPLACE_ELEM(head, el, add) \ do { \ LDECLTYPE(head) _tmp; \ assert(head != NULL); \ assert(el != NULL); \ assert(add != NULL); \ (add)->next = (el)->next; \ if ((head) == (el)) { \ (head) = (add); \ } else { \ _tmp = head; \ while (_tmp->next && (_tmp->next != (el))) { \ _tmp = _tmp->next; \ } \ if (_tmp->next) { \ _tmp->next = (add); \ } \ } \ } while (0) #define LL_PREPEND_ELEM(head, el, add) \ do { \ LDECLTYPE(head) _tmp; \ assert(head != NULL); \ assert(el != NULL); \ assert(add != NULL); \ (add)->next = (el); \ if ((head) == (el)) { \ (head) = (add); \ } else { \ _tmp = head; \ while (_tmp->next && (_tmp->next != (el))) { \ _tmp = _tmp->next; \ } \ if (_tmp->next) { \ _tmp->next = (add); \ } \ } \ } while (0) \ /****************************************************************************** * doubly linked list macros (non-circular) * *****************************************************************************/ #define DL_PREPEND(head,add) \ DL_PREPEND2(head,add,prev,next) #define DL_PREPEND2(head,add,prev,next) \ do { \ (add)->next = head; \ if (head) { \ (add)->prev = (head)->prev; \ (head)->prev = (add); \ } else { \ (add)->prev = (add); \ } \ (head) = (add); \ } while (0) #define DL_APPEND(head,add) \ DL_APPEND2(head,add,prev,next) #define DL_APPEND2(head,add,prev,next) \ do { \ if (head) { \ (add)->prev = (head)->prev; \ (head)->prev->next = (add); \ (head)->prev = (add); \ (add)->next = NULL; \ } else { \ (head)=(add); \ (head)->prev = (head); \ (head)->next = NULL; \ } \ } while (0) #define DL_CONCAT(head1,head2) \ DL_CONCAT2(head1,head2,prev,next) #define DL_CONCAT2(head1,head2,prev,next) \ do { \ LDECLTYPE(head1) _tmp; \ if (head2) { \ if (head1) { \ _tmp = (head2)->prev; \ (head2)->prev = (head1)->prev; \ (head1)->prev->next = (head2); \ (head1)->prev = _tmp; \ } else { \ (head1)=(head2); \ } \ } \ } while (0) #define DL_DELETE(head,del) \ DL_DELETE2(head,del,prev,next) #define DL_DELETE2(head,del,prev,next) \ do { \ assert((del)->prev != NULL); \ if ((del)->prev == (del)) { \ (head)=NULL; \ } else if ((del)==(head)) { \ (del)->next->prev = (del)->prev; \ (head) = (del)->next; \ } else { \ (del)->prev->next = (del)->next; \ if ((del)->next) { \ (del)->next->prev = (del)->prev; \ } else { \ (head)->prev = (del)->prev; \ } \ } \ } while (0) #define DL_COUNT(head,el,counter) \ DL_COUNT2(head,el,counter,next) \ #define DL_COUNT2(head,el,counter,next) \ { \ counter = 0; \ DL_FOREACH2(head,el,next){ ++counter; } \ } #define DL_FOREACH(head,el) \ DL_FOREACH2(head,el,next) #define DL_FOREACH2(head,el,next) \ for(el=head;el;el=(el)->next) /* this version is safe for deleting the elements during iteration */ #define DL_FOREACH_SAFE(head,el,tmp) \ DL_FOREACH_SAFE2(head,el,tmp,next) #define DL_FOREACH_SAFE2(head,el,tmp,next) \ for((el)=(head);(el) && (tmp = (el)->next, 1); (el) = tmp) /* these are identical to their singly-linked list counterparts */ #define DL_SEARCH_SCALAR LL_SEARCH_SCALAR #define DL_SEARCH LL_SEARCH #define DL_SEARCH_SCALAR2 LL_SEARCH_SCALAR2 #define DL_SEARCH2 LL_SEARCH2 #define DL_REPLACE_ELEM(head, el, add) \ do { \ assert(head != NULL); \ assert(el != NULL); \ assert(add != NULL); \ if ((head) == (el)) { \ (head) = (add); \ (add)->next = (el)->next; \ if ((el)->next == NULL) { \ (add)->prev = (add); \ } else { \ (add)->prev = (el)->prev; \ (add)->next->prev = (add); \ } \ } else { \ (add)->next = (el)->next; \ (add)->prev = (el)->prev; \ (add)->prev->next = (add); \ if ((el)->next == NULL) { \ (head)->prev = (add); \ } else { \ (add)->next->prev = (add); \ } \ } \ } while (0) #define DL_PREPEND_ELEM(head, el, add) \ do { \ assert(head != NULL); \ assert(el != NULL); \ assert(add != NULL); \ (add)->next = (el); \ (add)->prev = (el)->prev; \ (el)->prev = (add); \ if ((head) == (el)) { \ (head) = (add); \ } else { \ (add)->prev->next = (add); \ } \ } while (0) \ /****************************************************************************** * circular doubly linked list macros * *****************************************************************************/ #define CDL_PREPEND(head,add) \ CDL_PREPEND2(head,add,prev,next) #define CDL_PREPEND2(head,add,prev,next) \ do { \ if (head) { \ (add)->prev = (head)->prev; \ (add)->next = (head); \ (head)->prev = (add); \ (add)->prev->next = (add); \ } else { \ (add)->prev = (add); \ (add)->next = (add); \ } \ (head)=(add); \ } while (0) #define CDL_DELETE(head,del) \ CDL_DELETE2(head,del,prev,next) #define CDL_DELETE2(head,del,prev,next) \ do { \ if ( ((head)==(del)) && ((head)->next == (head))) { \ (head) = 0L; \ } else { \ (del)->next->prev = (del)->prev; \ (del)->prev->next = (del)->next; \ if ((del) == (head)) (head)=(del)->next; \ } \ } while (0) #define CDL_COUNT(head,el,counter) \ CDL_COUNT2(head,el,counter,next) \ #define CDL_COUNT2(head, el, counter,next) \ { \ counter = 0; \ CDL_FOREACH2(head,el,next){ ++counter; } \ } #define CDL_FOREACH(head,el) \ CDL_FOREACH2(head,el,next) #define CDL_FOREACH2(head,el,next) \ for(el=head;el;el=((el)->next==head ? 0L : (el)->next)) #define CDL_FOREACH_SAFE(head,el,tmp1,tmp2) \ CDL_FOREACH_SAFE2(head,el,tmp1,tmp2,prev,next) #define CDL_FOREACH_SAFE2(head,el,tmp1,tmp2,prev,next) \ for((el)=(head), ((tmp1)=(head)?((head)->prev):NULL); \ (el) && ((tmp2)=(el)->next, 1); \ ((el) = (((el)==(tmp1)) ? 0L : (tmp2)))) #define CDL_SEARCH_SCALAR(head,out,field,val) \ CDL_SEARCH_SCALAR2(head,out,field,val,next) #define CDL_SEARCH_SCALAR2(head,out,field,val,next) \ do { \ CDL_FOREACH2(head,out,next) { \ if ((out)->field == (val)) break; \ } \ } while(0) #define CDL_SEARCH(head,out,elt,cmp) \ CDL_SEARCH2(head,out,elt,cmp,next) #define CDL_SEARCH2(head,out,elt,cmp,next) \ do { \ CDL_FOREACH2(head,out,next) { \ if ((cmp(out,elt))==0) break; \ } \ } while(0) #define CDL_REPLACE_ELEM(head, el, add) \ do { \ assert(head != NULL); \ assert(el != NULL); \ assert(add != NULL); \ if ((el)->next == (el)) { \ (add)->next = (add); \ (add)->prev = (add); \ (head) = (add); \ } else { \ (add)->next = (el)->next; \ (add)->prev = (el)->prev; \ (add)->next->prev = (add); \ (add)->prev->next = (add); \ if ((head) == (el)) { \ (head) = (add); \ } \ } \ } while (0) #define CDL_PREPEND_ELEM(head, el, add) \ do { \ assert(head != NULL); \ assert(el != NULL); \ assert(add != NULL); \ (add)->next = (el); \ (add)->prev = (el)->prev; \ (el)->prev = (add); \ (add)->prev->next = (add); \ if ((head) == (el)) { \ (head) = (add); \ } \ } while (0) \ #endif /* UTLIST_H */ bcftools-1.21/variantkey.h000066400000000000000000000530101467060157400156070ustar00rootroot00000000000000// VariantKey // // variantkey.h // // @category Libraries // @author Nicola Asuni // @link https://github.com/tecnickcom/variantkey // @license MIT [LICENSE](https://raw.githubusercontent.com/tecnickcom/variantkey/main/LICENSE) // @copyright 2017-2018 GENOMICS plc, 2018-2023 Nicola Asuni - Tecnick.com // // LICENSE // // Copyright (c) 2017-2018 GENOMICS plc // Copyright (c) 2018-2023 Nicola Asuni - Tecnick.com // // Permission is hereby granted, free of charge, to any person obtaining a copy // of this software and associated documentation files (the "Software"), to deal // in the Software without restriction, including without limitation the rights // to use, copy, modify, merge, publish, distribute, sublicense, and/or sell // copies of the Software, and to permit persons to whom the Software is // furnished to do so, subject to the following conditions: // // The above copyright notice and this permission notice shall be included in // all copies or substantial portions of the Software. // // THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR // IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, // FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE // AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER // LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, // OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN // THE SOFTWARE. /** * @file variantkey.h * @brief VariantKey main functions. * * The functions provided here allow the generation and processing of a 64 bit Unsigned Integer Keys for Human Genetic Variants. * The VariantKey is sortable for chromosome and position, * and it is also fully reversible for variants with up to 11 bases between Reference and Alternate alleles. * It can be used to sort, search and match variant-based data easily and very quickly. */ #ifndef VARIANTKEY_H #define VARIANTKEY_H #include #include #include #include "hex.h" #define VKMASK_CHROM 0xF800000000000000 //!< VariantKey binary mask for CHROM [ 11111000 00000000 00000000 00000000 00000000 00000000 00000000 00000000 ] #define VKMASK_POS 0x07FFFFFF80000000 //!< VariantKey binary mask for POS [ 00000111 11111111 11111111 11111111 10000000 00000000 00000000 00000000 ] #define VKMASK_CHROMPOS 0xFFFFFFFF80000000 //!< VariantKey binary mask for CHROM+POS [ 11111111 11111111 11111111 11111111 10000000 00000000 00000000 00000000 ] #define VKMASK_REFALT 0x000000007FFFFFFF //!< VariantKey binary mask for REF+ALT [ 00000000 00000000 00000000 00000000 01111111 11111111 11111111 11111111 ] #define VKSHIFT_CHROM 59 //!< CHROM LSB position from the VariantKey LSB #define VKSHIFT_POS 31 //!< POS LSB position from the VariantKey LSB #define MAXUINT32 0xFFFFFFFF //!< Maximum value for uint32_t /** * VariantKey struct. * Contains the numerically encoded VariantKey components (CHROM, POS, REF+ALT). */ typedef struct variantkey_t { uint8_t chrom; //!< Chromosome encoded number (only the LSB 5 bit are used) uint32_t pos; //!< Reference position, with the first base having position 0 (only the LSB 28 bit are used) uint32_t refalt; //!< Code for Reference and Alternate allele (only the LSB 31 bits are used) } variantkey_t; /** * Struct containing the minimum and maximum VariantKey values for range searches. */ typedef struct vkrange_t { uint64_t min; //!< Minimum VariantKey value for any given REF+ALT encoding uint64_t max; //!< Maximum VariantKey value for any given REF+ALT encoding } vkrange_t; /** @brief Returns the encoding for a numerical chromosome input. * * @param chrom Chromosome. An identifier from the reference genome, no white-space permitted. * @param size Length of the chrom string, excluding the terminating null byte. * * @return CHROM code */ static inline uint8_t encode_numeric_chrom(const char *chrom, size_t size) { size_t i; uint8_t v = (chrom[0] - '0'); for (i = 1; i < size; i++) { if ((chrom[i] > '9') || (chrom[i] < '0')) { return 0; // NA: a character that is not a number was found. } v = ((v * 10) + (chrom[i] - '0')); } return v; } /** @brief Returns a true value (1) if the input chrom has 'chr' prefix (case insensitive). * * @param chrom Chromosome. An identifier from the reference genome, no white-space permitted. * @param size Length of the chrom string, excluding the terminating null byte. * * @return True (1) if the chr prefix is present. */ static inline int has_chrom_chr_prefix(const char *chrom, size_t size) { return ((size > 3) && ((chrom[0] == 'c') || (chrom[0] == 'C')) && ((chrom[1] == 'h') || (chrom[1] == 'H')) && ((chrom[2] == 'r') || (chrom[2] == 'R'))); } /** @brief Returns chromosome numerical encoding. * * @param chrom Chromosome. An identifier from the reference genome, no white-space permitted. * @param size Length of the chrom string, excluding the terminating null byte. * * @return CHROM code or 0 in case of invalid input. */ static inline uint8_t encode_chrom(const char *chrom, size_t size) { // X = 23; Y = 24; M = 25; any other letter is mapped to 0: static const uint8_t onecharmap[] = { 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, /* M X Y */ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0,25, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0,23,24, 0, 0, 0, 0, 0, 0, /* m x y */ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0,25, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0,23,24, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, }; if (has_chrom_chr_prefix(chrom, size)) { // remove "chr" prefix chrom += 3; size -= 3; } if (size == 0) { return 0; } if ((chrom[0] <= '9') && (chrom[0] >= '0')) { return encode_numeric_chrom(chrom, size); } if ((size == 1) || ((size == 2) && ((chrom[1] == 'T') || (chrom[1] == 't')))) { return onecharmap[((uint8_t)chrom[0])]; } return 0; // NA } /** @brief Decode the chromosome numerical code. * * @param code CHROM code. * @param chrom CHROM string buffer to be returned. Its size should be enough to contain the results (max 4 bytes). * * @return If successful, the total number of characters written is returned, * excluding the null-character appended at the end of the string, * otherwise a negative number is returned in case of failure. */ static inline size_t decode_chrom(uint8_t code, char *chrom) { if ((code < 1) || (code > 25)) { return sprintf(chrom, "NA"); } if (code < 23) { return sprintf(chrom, "%" PRIu8, code); } static const char *map[] = {"X", "Y", "MT"}; return sprintf(chrom, "%s", map[(code - 23)]); } static inline uint32_t encode_base(const uint8_t c) { /* Encode base: A = 0 C = 1 G = 2 T = 3 */ static const uint32_t map[] = { 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, /*A C G T*/ 4,0,4,1,4,4,4,2,4,4,4,4,4,4,4,4,4,4,4,4,3,4,4,4,4,4,4,4,4,4,4,4, /*a c g t*/ 4,0,4,1,4,4,4,2,4,4,4,4,4,4,4,4,4,4,4,4,3,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, }; return map[c]; } static inline int encode_allele(uint32_t *h, uint8_t *bitpos, const char *str, size_t size) { uint32_t v; while (size--) { v = encode_base(*str++); if (v > 3) { return -1; } *bitpos -= 2; *h |= (v << *bitpos); } return 0; } static inline uint32_t encode_refalt_rev(const char *ref, size_t sizeref, const char *alt, size_t sizealt) { //[******** ******** ******** ******** *RRRRAAA A1122334 45566778 8990011*] uint32_t h = 0; h |= ((uint32_t)(sizeref) << 27); // RRRR: length of (REF - 1) h |= ((uint32_t)(sizealt) << 23); // AAAA: length of (ALT - 1) uint8_t bitpos = 23; if ((encode_allele(&h, &bitpos, ref, sizeref) < 0) || (encode_allele(&h, &bitpos, alt, sizealt) < 0)) { return MAXUINT32; // error code } return h; } // Mix two 32 bit hash numbers using a MurmurHash3-like algorithm static inline uint32_t muxhash(uint32_t k, uint32_t h) { k *= 0xcc9e2d51; k = (k >> 17) | (k << 15); k *= 0x1b873593; h ^= k; h = (h >> 19) | (h << 13); return ((h * 5) + 0xe6546b64); } static inline uint32_t encode_packchar(int c) { if (c < 'A') { return 27; } if (c >= 'a') { return (uint32_t)(c - 'a' + 1); } return (uint32_t)(c - 'A' + 1); } // pack blocks of 6 characters in 32 bit (6 x 5 bit + 2 spare bit) [ 01111122 22233333 44444555 55666660 ] static inline uint32_t pack_chars_tail(const char *str, size_t size) { uint32_t h = 0; const char *pos = (str + size - 1); switch (size) { case 5: h ^= encode_packchar(*pos--) << (1 + (5 * 1)); // fall through case 4: h ^= encode_packchar(*pos--) << (1 + (5 * 2)); // fall through case 3: h ^= encode_packchar(*pos--) << (1 + (5 * 3)); // fall through case 2: h ^= encode_packchar(*pos--) << (1 + (5 * 4)); // fall through case 1: h ^= encode_packchar(*pos) << (1 + (5 * 5)); } return h; } static inline uint32_t pack_chars(const char *str) { const char *pos = (str + 5); return ((encode_packchar(*pos) << 1) ^ (encode_packchar(*(pos-1)) << (1 + (5 * 1))) ^ (encode_packchar(*(pos-2)) << (1 + (5 * 2))) ^ (encode_packchar(*(pos-3)) << (1 + (5 * 3))) ^ (encode_packchar(*(pos-4)) << (1 + (5 * 4))) ^ (encode_packchar(*(pos-5)) << (1 + (5 * 5)))); } // Return a 32 bit hash of a nucleotide string static inline uint32_t hash32(const char *str, size_t size) { uint32_t h = 0; size_t len = 6; while (size >= len) { h = muxhash(pack_chars(str), h); str += len; size -= len; } if (size > 0) { h = muxhash(pack_chars_tail(str, size), h); } return h; } static inline uint32_t encode_refalt_hash(const char *ref, size_t sizeref, const char *alt, size_t sizealt) { // 0x3 is the separator character between REF and ALT [00000000 00000000 00000000 00000011] uint32_t h = muxhash(hash32(alt, sizealt), muxhash(0x3, hash32(ref, sizeref))); // MurmurHash3 finalization mix - force all bits of a hash block to avalanche h ^= h >> 16; h *= 0x85ebca6b; h ^= h >> 13; h *= 0xc2b2ae35; h ^= h >> 16; return ((h >> 1) | 0x1); // 0x1 is the set bit to indicate HASH mode [00000000 00000000 00000000 00000001] } /** @brief Returns reference+alternate numerical encoding. * * @param ref Reference allele. String containing a sequence of nucleotide letters. * The value in the pos field refers to the position of the first nucleotide in the String. * Characters must be A-Z, a-z or * * @param sizeref Length of the ref string, excluding the terminating null byte. * @param alt Alternate non-reference allele string. * Characters must be A-Z, a-z or * * @param sizealt Length of the alt string, excluding the terminating null byte. * * @return REF+ALT code */ static inline uint32_t encode_refalt(const char *ref, size_t sizeref, const char *alt, size_t sizealt) { if ((sizeref + sizealt) <= 11) { uint32_t h = encode_refalt_rev(ref, sizeref, alt, sizealt); if (h != MAXUINT32) { return h; } } return encode_refalt_hash(ref, sizeref, alt, sizealt); } static inline char decode_base(uint32_t code, int bitpos) { static const char base[4] = {'A', 'C', 'G', 'T'}; return base[((code >> bitpos) & 0x3)]; // 0x3 is the 2 bit mask [00000011] } static inline size_t decode_refalt_rev(uint32_t code, char *ref, size_t *sizeref, char *alt, size_t *sizealt) { *sizeref = (size_t)((code & 0x78000000) >> 27); // [01111000 00000000 00000000 00000000] *sizealt = (size_t)((code & 0x07800000) >> 23); // [00000111 10000000 00000000 00000000] switch (*sizeref) { case 10: ref[9] = decode_base(code, (3 + (2 * 0))); // fall through case 9: ref[8] = decode_base(code, (3 + (2 * 1))); // fall through case 8: ref[7] = decode_base(code, (3 + (2 * 2))); // fall through case 7: ref[6] = decode_base(code, (3 + (2 * 3))); // fall through case 6: ref[5] = decode_base(code, (3 + (2 * 4))); // fall through case 5: ref[4] = decode_base(code, (3 + (2 * 5))); // fall through case 4: ref[3] = decode_base(code, (3 + (2 * 6))); // fall through case 3: ref[2] = decode_base(code, (3 + (2 * 7))); // fall through case 2: ref[1] = decode_base(code, (3 + (2 * 8))); // fall through case 1: ref[0] = decode_base(code, (3 + (2 * 9))); } ref[*sizeref] = 0; uint8_t bitpos = (23 - ((*sizeref) << 1)); switch (*sizealt) { case 10: alt[9] = decode_base(code, bitpos - (2 * 10)); // fall through case 9: alt[8] = decode_base(code, bitpos - (2 * 9)); // fall through case 8: alt[7] = decode_base(code, bitpos - (2 * 8)); // fall through case 7: alt[6] = decode_base(code, bitpos - (2 * 7)); // fall through case 6: alt[5] = decode_base(code, bitpos - (2 * 6)); // fall through case 5: alt[4] = decode_base(code, bitpos - (2 * 5)); // fall through case 4: alt[3] = decode_base(code, bitpos - (2 * 4)); // fall through case 3: alt[2] = decode_base(code, bitpos - (2 * 3)); // fall through case 2: alt[1] = decode_base(code, bitpos - (2 * 2)); // fall through case 1: alt[0] = decode_base(code, bitpos - (2 * 1)); } alt[*sizealt] = 0; return (*sizeref + *sizealt); } /** @brief Decode the 32 bit REF+ALT code if reversible (if it has 11 or less bases in total and only contains ACGT letters). * * @param code REF+ALT code * @param ref REF string buffer to be returned. * @param sizeref Pointer to the size of the ref buffer, excluding the terminating null byte. * This will contain the final ref size. * @param alt ALT string buffer to be returned. * @param sizealt Pointer to the size of the alt buffer, excluding the terminating null byte. * This will contain the final alt size. * * @return If the code is reversible, then the total number of characters of REF+ALT is returned. * Otherwise 0 is returned. */ static inline size_t decode_refalt(uint32_t code, char *ref, size_t *sizeref, char *alt, size_t *sizealt) { if (code & 0x1) // check last bit { return 0; // non-reversible encoding } return decode_refalt_rev(code, ref, sizeref, alt, sizealt); } /** @brief Returns a 64 bit variant key based on the pre-encoded CHROM, POS (0-based) and REF+ALT. * * @param chrom Encoded Chromosome (see encode_chrom). * @param pos Position. The reference position, with the first base having position 0. * @param refalt Encoded Reference + Alternate (see encode_refalt). * * @return VariantKey 64 bit code. */ static inline uint64_t encode_variantkey(uint8_t chrom, uint32_t pos, uint32_t refalt) { return (((uint64_t)chrom << VKSHIFT_CHROM) | ((uint64_t)pos << VKSHIFT_POS) | (uint64_t)refalt); } /** @brief Extract the CHROM code from VariantKey. * * @param vk VariantKey code. * * @return CHROM code. */ static inline uint8_t extract_variantkey_chrom(uint64_t vk) { return (uint8_t)((vk & VKMASK_CHROM) >> VKSHIFT_CHROM); } /** @brief Extract the POS code from VariantKey. * * @param vk VariantKey code. * * @return POS. */ static inline uint32_t extract_variantkey_pos(uint64_t vk) { return (uint32_t)((vk & VKMASK_POS) >> VKSHIFT_POS); } /** @brief Extract the REF+ALT code from VariantKey. * * @param vk VariantKey code. * * @return REF+ALT code. */ static inline uint32_t extract_variantkey_refalt(uint64_t vk) { return (uint32_t)(vk & VKMASK_REFALT); } /** @brief Decode a VariantKey code and returns the components as variantkey_t structure. * * @param code VariantKey code. * @param vk Decoded variantkey structure. */ static inline void decode_variantkey(uint64_t code, variantkey_t *vk) { vk->chrom = extract_variantkey_chrom(code); vk->pos = extract_variantkey_pos(code); vk->refalt = extract_variantkey_refalt(code); } /** * Returns a 64 bit variant key based on CHROM, POS (0-based), REF, ALT. * The variant should be already normalized (see normalize_variant or use normalized_variantkey). * * @param chrom Chromosome. An identifier from the reference genome, no white-space or leading zeros permitted. * @param sizechrom Length of the chrom string, excluding the terminating null byte. * @param pos Position. The reference position, with the first base having position 0. * @param ref Reference allele. String containing a sequence of nucleotide letters. * The value in the pos field refers to the position of the first nucleotide in the String. * Characters must be A-Z, a-z or * * @param sizeref Length of the ref string, excluding the terminating null byte. * @param alt Alternate non-reference allele string. * Characters must be A-Z, a-z or * * @param sizealt Length of the alt string, excluding the terminating null byte. * * @return VariantKey 64 bit code. */ static inline uint64_t variantkey(const char *chrom, size_t sizechrom, uint32_t pos, const char *ref, size_t sizeref, const char *alt, size_t sizealt) { return encode_variantkey(encode_chrom(chrom, sizechrom), pos, encode_refalt(ref, sizeref, alt, sizealt)); } /** @brief Returns minimum and maximum VariantKeys for range searches. * * @param chrom Chromosome encoded number. * @param pos_min Start reference position, with the first base having position 0. * @param pos_max End reference position, with the first base having position 0. * @param range VariantKey range values. */ static inline void variantkey_range(uint8_t chrom, uint32_t pos_min, uint32_t pos_max, vkrange_t *range) { uint64_t c = ((uint64_t)chrom << VKSHIFT_CHROM); range->min = (c | ((uint64_t)pos_min << VKSHIFT_POS)); range->max = (c | ((uint64_t)pos_max << VKSHIFT_POS) | VKMASK_REFALT); } static inline int8_t compare_uint64_t(uint64_t a, uint64_t b) { return (a < b) ? -1 : (a > b); } /** @brief Compares two VariantKeys by chromosome only. * * @param vka The first VariantKey to be compared. * @param vkb The second VariantKey to be compared. * * @return -1 if the first chromosome is smaller than the second, 0 if they are equal and 1 if the first is greater than the second. */ static inline int8_t compare_variantkey_chrom(uint64_t vka, uint64_t vkb) { return compare_uint64_t((vka >> VKSHIFT_CHROM), (vkb >> VKSHIFT_CHROM)); } /** @brief Compares two VariantKeys by chromosome and position. * * @param vka The first VariantKey to be compared. * @param vkb The second VariantKey to be compared. * * @return -1 if the first CHROM+POS is smaller than the second, 0 if they are equal and 1 if the first is greater than the second. */ static inline int8_t compare_variantkey_chrom_pos(uint64_t vka, uint64_t vkb) { return compare_uint64_t((vka >> VKSHIFT_POS), (vkb >> VKSHIFT_POS)); } /** @brief Returns VariantKey hexadecimal string (16 characters). * * The string represent a 64 bit number or: * - 5 bit for CHROM * - 28 bit for POS * - 31 bit for REF+ALT * * @param vk VariantKey code. * @param str String buffer to be returned (it must be sized 17 bytes at least). * * @return Upon successful return, these function returns the number of characters processed * (excluding the null byte used to end output to strings). * If the buffer size is not sufficient, then the return value is the number of characters required for * buffer string, including the terminating null byte. */ static inline size_t variantkey_hex(uint64_t vk, char *str) { return hex_uint64_t(vk, str); } /** @brief Parses a VariantKey hexadecimal string and returns the code. * * @param vs VariantKey hexadecimal string (it must contain 16 hexadecimal characters). * * @return A VariantKey code. */ static inline uint64_t parse_variantkey_hex(const char *vs) { return parse_hex_uint64_t(vs); } #endif // VARIANTKEY_H bcftools-1.21/vcfannotate.c000066400000000000000000005115321467060157400157450ustar00rootroot00000000000000/* vcfannotate.c -- Annotate and edit VCF/BCF files. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "vcmp.h" #include "filter.h" #include "convert.h" #include "smpl_ilist.h" #include "regidx.h" #include "dbuf.h" struct _args_t; typedef struct _rm_tag_t { char *key; int hdr_id; void (*handler)(struct _args_t *, bcf1_t *, struct _rm_tag_t *); } rm_tag_t; typedef struct { char **cols; int ncols, mcols; char **als; int nals, mals; kstring_t line; int rid, start, end; } annot_line_t; #define REPLACE_MISSING (1<<0) // -c +TAG .. replace only missing values #define REPLACE_ALL (1<<1) // -c TAG .. replace both missing and existing values #define REPLACE_NON_MISSING (1<<2) // -c -TAG .. replace only if tgt is not missing #define SET_OR_APPEND (1<<3) // -c =TAG .. set new value if missing or non-existent, append otherwise #define MATCH_VALUE (1<<4) // -c ~ID .. do not set, just match the value #define CARRY_OVER_MISSING (1<<5) // -c .TAG .. carry over source missing values as well #define MM_FIRST 0 // if multiple annotation lines overlap a VCF record, use the first, discarding the rest #define MM_APPEND 1 // append, possibly multiple times #define MM_UNIQUE 2 // append, only unique values #define MM_SUM 3 #define MM_AVG 4 #define MM_MIN 5 #define MM_MAX 6 #define MM_APPEND_MISSING 7 // missing values will be transferred as well typedef struct _annot_col_t { int icol, replace, number; // number: one of BCF_VL_* types char *hdr_key_src, *hdr_key_dst; // The setters return 0 on successful update of the bcf record, negative value (bcf_update_* return status) on errors, // or 1 on (repeated partial updates) concluded with a src=NULL call int (*setter)(struct _args_t *, bcf1_t *dst, struct _annot_col_t *, void *src); // the last is the annotation line, either src bcf1_t or annot_line_t int (*getter)(struct _args_t *, bcf1_t *src, struct _annot_col_t *, void **ptr, int *mptr); int merge_method; // one of the MM_* defines khash_t(str2int) *mm_str_hash; // lookup table to ensure uniqueness of added string values kstring_t mm_kstr; size_t mm_dbl_nalloc, // the allocated size --merge-logic values array mm_dbl_nused, // the number of used elements in the mm_dbl array mm_dbl_ndat; // the number of merged rows (for calculating the average) double *mm_dbl; void *ptr; int mptr, done; } annot_col_t; typedef struct { char *name; // column name int ht_type; // type, one of BCF_HT_STR,BCF_HT_INT,BCF_HT_REAL int icol; // index of the annotation column to use union { // memory area with the current annotation value to pass to filter_test_ext int i; float f; char *s; }; } ext_t; // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define MARK_LISTED 1 #define MARK_UNLISTED 2 typedef struct _args_t { bcf_srs_t *files; bcf_hdr_t *hdr, *hdr_out, *tgts_hdr; htsFile *out_fh; int output_type, n_threads, clevel; bcf_sr_regions_t *tgts; char *index_fn; int write_index; regidx_t *tgt_idx; // keep everything in memory only with .tab annotation file and -c BEG,END columns regitr_t *tgt_itr; int tgt_is_bed; filter_t *filter, *filter_ext; // only one is initialized, the latter contains external values to set dynamically on the fly char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE int keep_sites; rm_tag_t *rm; // tags scheduled for removal int nrm; int flt_keep_pass; // when all filters removed, reset to PASS vcmp_t *vcmp; // for matching annotation and VCF lines by allele annot_line_t *alines; // buffered annotation lines annot_line_t *aline_missing; uint32_t *srt_alines; // sorted indexes (iALT<<16 || iAline) int nalines, malines, nsrt_alines, msrt_alines; int ref_idx, alt_idx, chr_idx, beg_idx, end_idx; // -1 if not present annot_col_t *cols; // column indexes and setters int ncols; int match_id; // set iff `-c ~ID` given, -1 otherwise int match_end; // set iff `-c ~INFO/END` is given, -1 otherwise char *set_ids_fmt; convert_t *set_ids; int set_ids_replace; // external values for dynamic -i/-e expressions int n_ext; ext_t *ext; void **ext_ptr; int nsmpl_annot; int *sample_map, nsample_map, sample_is_file; // map[idst] -> isrc uint8_t *src_smpl_pld, *dst_smpl_pld; // for Number=G format fields int mtmpi, mtmpf, mtmps; int mtmpi2, mtmpf2, mtmps2; int mtmpi3, mtmpf3, mtmps3; int32_t *tmpi, *tmpi2, *tmpi3; float *tmpf, *tmpf2, *tmpf3; char *tmps, *tmps2, **tmpp, **tmpp2; kstring_t tmpks; char **argv, *output_fname, *targets_fname, *regions_list, *header_fname; char *remove_annots, *columns, *rename_chrs, *rename_annots, *sample_names, *mark_sites; char **rename_annots_map; char *min_overlap_str; float min_overlap_ann, min_overlap_vcf; int rename_annots_nmap; kstring_t merge_method_str; int argc, drop_header, record_cmd_line, tgts_is_vcf, mark_sites_logic, force, single_overlaps; int columns_is_file, has_append_mode, pair_logic; dbuf_t *header_lines; bcf1_t *current_rec; // current record for local setters } args_t; char *msprintf(const char *fmt, ...); int parse_with_payload(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { args_t *args = (args_t*) usr; int ret = args->tgt_is_bed ? regidx_parse_bed(line, chr_beg, chr_end, beg, end, NULL, NULL) : regidx_parse_tab(line, chr_beg, chr_end, beg, end, NULL, NULL); if ( ret<0 ) return ret; *((char **)payload) = strdup(line); return 0; } void free_payload(void *payload) { char *str = *((char**)payload); free(str); } void remove_id(args_t *args, bcf1_t *line, rm_tag_t *tag) { bcf_update_id(args->hdr,line,NULL); } void remove_filter(args_t *args, bcf1_t *line, rm_tag_t *tag) { if ( tag->key && tag->hdr_id<0 ) { error("Error: Cannot proceed, not even with the --force option, bad things could happen.\n" " Note that \"bcftools annotate -x FILTER\" can be used to remove ALL filters.\n" " Even better, use \"bcftools view -h\" and \"bcftools reheader\" to fix the header!\n" ); } if ( !tag->key ) bcf_update_filter(args->hdr, line, NULL, args->flt_keep_pass); else bcf_remove_filter(args->hdr, line, tag->hdr_id, args->flt_keep_pass); } void remove_qual(args_t *args, bcf1_t *line, rm_tag_t *tag) { bcf_float_set_missing(line->qual); } void remove_info(args_t *args, bcf1_t *line, rm_tag_t *tag) { // remove all INFO fields if ( !(line->unpacked & BCF_UN_INFO) ) bcf_unpack(line, BCF_UN_INFO); int i; for (i=0; in_info; i++) { bcf_info_t *inf = &line->d.info[i]; if ( !strcmp("END",bcf_hdr_int2id(args->hdr,BCF_DT_ID,inf->key)) ) line->rlen = line->n_allele ? strlen(line->d.allele[0]) : 0; if ( inf->vptr_free ) { free(inf->vptr - inf->vptr_off); inf->vptr_free = 0; } line->d.shared_dirty |= BCF1_DIRTY_INF; inf->vptr = NULL; inf->vptr_off = inf->vptr_len = 0; } } void remove_info_tag(args_t *args, bcf1_t *line, rm_tag_t *tag) { bcf_update_info(args->hdr, line, tag->key, NULL, 0, BCF_HT_INT); // the type does not matter with n=0 } void remove_format_tag(args_t *args, bcf1_t *line, rm_tag_t *tag) { bcf_update_format(args->hdr, line, tag->key, NULL, 0, BCF_HT_INT); // the type does not matter with n=0 } void remove_format(args_t *args, bcf1_t *line, rm_tag_t *tag) { // remove all FORMAT fields except GT if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); int i; for (i=0; in_fmt; i++) { bcf_fmt_t *fmt = &line->d.fmt[i]; const char *key = bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id); if ( key[0]=='G' && key[1]=='T' && !key[2] ) continue; if ( fmt->p_free ) { free(fmt->p - fmt->p_off); fmt->p_free = 0; } line->d.indiv_dirty = 1; fmt->p = NULL; } } #include "htslib/khash.h" KHASH_MAP_INIT_STR(vdict, bcf_idinfo_t) typedef khash_t(vdict) vdict_t; static void remove_hdr_lines(bcf_hdr_t *hdr, int type) { int i = 0, nrm = 0; while ( inhrec ) { if ( hdr->hrec[i]->type!=type ) { i++; continue; } bcf_hrec_t *hrec = hdr->hrec[i]; if ( type==BCF_HL_FMT || type==BCF_HL_INFO || type==BCF_HL_FMT || type== BCF_HL_CTG ) { // everything except FORMAT/GT int id = bcf_hrec_find_key(hrec, "ID"); if ( id>=0 ) { if ( type==BCF_HL_FMT && !strcmp(hrec->vals[id],"GT") ) { i++; continue; } vdict_t *d = type==BCF_HL_CTG ? (vdict_t*)hdr->dict[BCF_DT_CTG] : (vdict_t*)hdr->dict[BCF_DT_ID]; khint_t k = kh_get(vdict, d, hdr->hrec[i]->vals[id]); kh_val(d, k).hrec[type==BCF_HL_CTG?0:type] = NULL; kh_val(d, k).info[type] |= 0xf; } } nrm++; hdr->nhrec--; if ( i < hdr->nhrec ) memmove(&hdr->hrec[i],&hdr->hrec[i+1],(hdr->nhrec-i)*sizeof(bcf_hrec_t*)); bcf_hrec_destroy(hrec); } if ( nrm ) { if (bcf_hdr_sync(hdr) < 0) error_errno("[%s] Failed to update header", __func__); } } static void init_remove_annots(args_t *args) { int keep_info = 0, keep_fmt = 0, keep_flt = 0; void *keep = khash_str2int_init(); kstring_t str = {0,0,0}; char *ss = args->remove_annots; int i, ntags, needs_info = 0; if ( args->set_ids ) { const char **tags = convert_list_used_tags(args->set_ids,&ntags); for (i=0; inrm++; args->rm = (rm_tag_t*) realloc(args->rm,sizeof(rm_tag_t)*args->nrm); rm_tag_t *tag = &args->rm[args->nrm-1]; tag->key = NULL; int type = BCF_HL_GEN; if ( !strncasecmp("INFO/",ss,5) ) { type = BCF_HL_INFO; ss += 5; } else if ( !strncasecmp("INF/",ss,4) ) { type = BCF_HL_INFO; ss += 4; } else if ( !strncasecmp("FORMAT/",ss,7) ) { type = BCF_HL_FMT; ss += 7; } else if ( !strncasecmp("FMT/",ss,4) ) { type = BCF_HL_FMT; ss += 4; } else if ( !strncasecmp("FILTER/",ss,7) ) { type = BCF_HL_FLT; ss += 7; } else if ( !strncasecmp("^INFO/",ss,6) ) { type = BCF_HL_INFO; ss += 6; keep_info = 1; } else if ( !strncasecmp("^INF/",ss,5) ) { type = BCF_HL_INFO; ss += 5; keep_info = 1; } else if ( !strncasecmp("^FORMAT/",ss,8) ) { type = BCF_HL_FMT; ss += 8; keep_fmt = 1; } else if ( !strncasecmp("^FMT/",ss,5) ) { type = BCF_HL_FMT; ss += 5; keep_fmt = 1; } else if ( !strncasecmp("^FILTER/",ss,8) ) { type = BCF_HL_FLT; ss += 8; keep_flt = 1; } char *se = ss; while ( *se && *se!=',' ) se++; str.l = 0; kputsn(ss, se-ss, &str); if ( type==BCF_HL_FLT ) { if ( !keep_flt ) { args->flt_keep_pass = 1; tag->handler = remove_filter; tag->key = strdup(str.s); tag->hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, tag->key); if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FLT,tag->hdr_id) ) { if ( args->keep_sites ) error("Error: The filter \"%s\" is not defined in the header, cannot use the -k option\n", str.s); else fprintf(stderr,"Warning: The filter \"%s\" is not defined in the header\n", str.s); } else if ( !args->keep_sites ) bcf_hdr_remove(args->hdr_out,BCF_HL_FLT,tag->key); } else { int value, ret = khash_str2int_get(keep, str.s, &value); if ( ret==-1 ) khash_str2int_set(keep, strdup(str.s),1<nrm--; } } else if ( type!=BCF_HL_GEN ) { int id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,str.s); if ( !bcf_hdr_idinfo_exists(args->hdr,type,id) ) { if ( args->keep_sites ) error("Error: The tag \"%s\" is not defined in the header, cannot use the -k option\n", str.s); else fprintf(stderr,"Warning: The tag \"%s\" not defined in the header\n", str.s); tag->key = strdup(str.s); if ( type==BCF_HL_INFO ) { tag->handler = remove_info_tag; if ( needs_info ) error("Error: `--remove INFO/%s` is executed first, cannot combine with `--set-id %s`\n",tag->key,args->set_ids_fmt); } else if ( type==BCF_HL_FMT ) tag->handler = remove_format_tag; } else if ( (type==BCF_HL_FMT && keep_fmt) || (type==BCF_HL_INFO && keep_info) ) { int value, ret = khash_str2int_get(keep, str.s, &value); if ( ret==-1 ) khash_str2int_set(keep, strdup(str.s),1<nrm--; } else { tag->key = strdup(str.s); if ( type==BCF_HL_INFO ) { tag->handler = remove_info_tag; if ( needs_info ) error("Error: `--remove INFO/%s` is executed first, cannot combine with `--set-id %s`\n",tag->key,args->set_ids_fmt); } else if ( type==BCF_HL_FMT ) tag->handler = remove_format_tag; if ( !args->keep_sites ) bcf_hdr_remove(args->hdr_out,type,tag->key); } } else if ( !strcasecmp("ID",str.s) ) tag->handler = remove_id; else if ( !strcasecmp("FILTER",str.s) ) { tag->handler = remove_filter; if ( !args->keep_sites ) remove_hdr_lines(args->hdr_out,BCF_HL_FLT); } else if ( !strcasecmp("QUAL",str.s) ) tag->handler = remove_qual; else if ( !strcasecmp("INFO",str.s) ) { if ( needs_info ) error("Error: `--remove INFO` is executed first, cannot combine with `--set-id %s`\n",args->set_ids_fmt); tag->handler = remove_info; if ( !args->keep_sites ) remove_hdr_lines(args->hdr_out,BCF_HL_INFO); } else if ( !strcasecmp("FMT",str.s) || !strcasecmp("FORMAT",str.s) ) { tag->handler = remove_format; if ( !args->keep_sites ) remove_hdr_lines(args->hdr_out,BCF_HL_FMT); } else if ( str.l ) { int id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, str.s); if ( bcf_hdr_idinfo_exists(args->hdr,BCF_HL_INFO,id) ) error("Error: did you mean INFO/%s?\n",str.s); if ( bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,id) ) error("Error: did you mean FORMAT/%s?\n",str.s); if ( !args->keep_sites ) { if ( str.s[0]=='#' && str.s[1]=='#' ) bcf_hdr_remove(args->hdr_out,BCF_HL_GEN,str.s+2); else bcf_hdr_remove(args->hdr_out,BCF_HL_STR,str.s); } args->nrm--; } ss = *se ? se+1 : se; } free(str.s); if ( keep_flt || keep_info || keep_fmt ) { int j; for (j=0; jhdr->nhrec; j++) { bcf_hrec_t *hrec = args->hdr->hrec[j]; if ( hrec->type!=BCF_HL_FLT && hrec->type!=BCF_HL_INFO && hrec->type!=BCF_HL_FMT ) continue; if ( !keep_flt && hrec->type==BCF_HL_FLT ) continue; if ( !keep_info && hrec->type==BCF_HL_INFO ) continue; if ( !keep_fmt && hrec->type==BCF_HL_FMT ) continue; int k = bcf_hrec_find_key(hrec,"ID"); assert( k>=0 ); // this should always be true for valid VCFs int value, ret = khash_str2int_get(keep,hrec->vals[k],&value); if ( ret==0 && value>>hrec->type ) // keep { if ( hrec->type==BCF_HL_FLT && !strcmp("PASS",hrec->vals[k]) ) args->flt_keep_pass = 1; continue; } args->nrm++; args->rm = (rm_tag_t*) realloc(args->rm,sizeof(rm_tag_t)*args->nrm); rm_tag_t *tag = &args->rm[args->nrm-1]; if ( hrec->type==BCF_HL_INFO ) tag->handler = remove_info_tag; else if ( hrec->type==BCF_HL_FMT ) tag->handler = remove_format_tag; else { tag->handler = remove_filter; tag->hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, hrec->vals[k]); } tag->key = strdup(hrec->vals[k]); if ( !args->keep_sites ) bcf_hdr_remove(args->hdr_out,hrec->type,tag->key); } } khash_str2int_destroy_free(keep); if ( !args->nrm ) error("No matching tag in -x %s\n", args->remove_annots); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); } static void init_header_lines(args_t *args) { if ( args->header_fname ) { htsFile *file = hts_open(args->header_fname, "rb"); if ( !file ) error("Error reading %s\n", args->header_fname); kstring_t str = {0,0,0}; while ( hts_getline(file, KS_SEP_LINE, &str) > 0 ) { if ( bcf_hdr_append(args->hdr_out,str.s) ) error("Could not parse %s: %s\n", args->header_fname, str.s); bcf_hdr_append(args->hdr,str.s); // the input file may not have the header line if run with -h (and nothing else) } if ( hts_close(file)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->header_fname); free(str.s); } if ( args->header_lines ) { int i, n = dbuf_n(args->header_lines); for (i=0; iheader_lines,i); if ( bcf_hdr_append(args->hdr_out,line) ) error("Could not parse the header line: %s\n", line); bcf_hdr_append(args->hdr,line); // the input file may not have the header line if run with -H (and nothing else) } dbuf_destroy_free(args->header_lines); args->header_lines = NULL; } if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update output header", __func__); if (bcf_hdr_sync(args->hdr) < 0) error_errno("[%s] Failed to update input header", __func__); } static int vcf_getter_info_str2str(args_t *args, bcf1_t *rec, annot_col_t *col, void **ptr, int *mptr) { return bcf_get_info_string(args->tgts_hdr,rec,col->hdr_key_src,ptr,mptr); } static int vcf_getter_id2str(args_t *args, bcf1_t *rec, annot_col_t *col, void **ptr, int *mptr) { char *str = *((char**)ptr); int i, len = strlen(rec->d.id); if ( len >= *mptr ) str = realloc(str, len+1); for (i=0; id.id[i]==';' ? ',' : rec->d.id[i]; str[len] = 0; *((char**)ptr) = str; *mptr = len+1; return len; } inline static int vcf_getter_filter2str_core(bcf_hdr_t *hdr, bcf1_t *rec, char **ptr, int *mptr) { if ( !(rec->unpacked & BCF_UN_FLT) ) bcf_unpack(rec, BCF_UN_FLT); kstring_t str; str.s = *ptr; str.m = *mptr; str.l = 0; int i; if ( rec->d.n_flt ) { for (i=0; id.n_flt; i++) { if (i) kputc(',', &str); kputs(bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.flt[i]), &str); } } else kputc('.', &str); *ptr = str.s; *mptr = str.m; return str.l; } static int vcf_getter_filter2str_local(args_t *args, bcf1_t *rec, annot_col_t *col, void **ptr, int *mptr) { return vcf_getter_filter2str_core(args->hdr_out, args->current_rec, (char**)ptr, mptr); } static int vcf_getter_filter2str(args_t *args, bcf1_t *rec, annot_col_t *col, void **ptr, int *mptr) { return vcf_getter_filter2str_core(args->tgts_hdr, rec, (char**)ptr, mptr); } static int setter_filter(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with FILTER (yet?)\n"); // note: so far this works only with one filter, not a list of filters annot_line_t *tab = (annot_line_t*) data; if ( tab->cols[col->icol][0]=='.' && !tab->cols[col->icol][1] ) // don't overwrite with a missing value unless asked { if ( (col->replace & CARRY_OVER_MISSING) && (col->replace & (REPLACE_ALL|REPLACE_NON_MISSING)) ) bcf_update_filter(args->hdr_out,line,NULL,0); return 0; } hts_expand(int,1,args->mtmpi,args->tmpi); args->tmpi[0] = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, tab->cols[col->icol]); if ( args->tmpi[0]<0 ) error("The FILTER \"%s\" is not defined in the header, was the -h option provided?\n", tab->cols[col->icol]); if ( col->replace & SET_OR_APPEND ) return bcf_add_filter(args->hdr_out,line,args->tmpi[0]); if ( !(col->replace & REPLACE_MISSING) ) { bcf_update_filter(args->hdr_out,line,NULL,0); return bcf_update_filter(args->hdr_out,line,args->tmpi,1); } // only update missing FILTER if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT); if ( !line->d.n_flt ) return bcf_update_filter(args->hdr_out,line,args->tmpi,1); return 0; } static int vcf_setter_filter(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { int i, ret = 0; bcf1_t *rec = (bcf1_t*) data; if ( !(rec->unpacked & BCF_UN_FLT) ) bcf_unpack(rec, BCF_UN_FLT); if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT); if ( !rec->d.n_flt ) // don't overwrite with a missing value unless asked { if ( (col->replace & CARRY_OVER_MISSING) && (col->replace & (REPLACE_ALL|REPLACE_NON_MISSING)) ) bcf_update_filter(args->hdr_out,line,NULL,0); return 0; } if ( col->replace & (SET_OR_APPEND|REPLACE_MISSING) ) { if ( (col->replace & REPLACE_MISSING) && line->d.n_flt ) return 0; // only update missing FILTER for (i=0; id.n_flt; i++) { const char *flt = bcf_hdr_int2id(args->files->readers[1].header, BCF_DT_ID, rec->d.flt[i]); if ( bcf_add_filter(args->hdr_out,line,bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, flt)) < 0 ) ret = -1; } return ret; } hts_expand(int,rec->d.n_flt,args->mtmpi,args->tmpi); for (i=0; id.n_flt; i++) { const char *flt = bcf_hdr_int2id(args->files->readers[1].header, BCF_DT_ID, rec->d.flt[i]); args->tmpi[i] = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, flt); } bcf_update_filter(args->hdr_out,line,NULL,0); return bcf_update_filter(args->hdr_out,line,args->tmpi,rec->d.n_flt); } static int setter_pos(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { annot_line_t *tab = (annot_line_t*) data; if ( tab->cols[col->icol] && tab->cols[col->icol][0]=='.' && !tab->cols[col->icol][1] ) return 0; // don't replace with "." char *tmp; int pos = strtol(tab->cols[col->icol], &tmp, 10); if ( tmp==tab->cols[col->icol] ) error("Could not parse -POS at %s:%"PRId64" .. [%s]\n",bcf_seqname(args->hdr,line),(int64_t)line->pos+1,tab->cols[col->icol]); line->pos = pos - 1; return 0; } static int setter_id(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with ID (yet?)\n"); if ( col->replace & MATCH_VALUE ) return 0; // possible cases: // IN ANNOT OUT ACHIEVED_BY // x y x -c +ID // x y y -c ID // x y x,y -c =ID // x . x -c +ID, ID // x . . -x ID // . y y -c +ID, -c ID // annot_line_t *tab = (annot_line_t*) data; if ( tab->cols[col->icol] && tab->cols[col->icol][0]=='.' && !tab->cols[col->icol][1] ) return 0; // don't replace with "." if ( col->replace & SET_OR_APPEND ) return bcf_add_id(args->hdr_out,line,tab->cols[col->icol]); if ( !(col->replace & REPLACE_MISSING) ) return bcf_update_id(args->hdr_out,line,tab->cols[col->icol]); // running with +ID, only update missing ids if ( !line->d.id || (line->d.id[0]=='.' && !line->d.id[1]) ) return bcf_update_id(args->hdr_out,line,tab->cols[col->icol]); return 0; } static int vcf_setter_id(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( col->replace & MATCH_VALUE ) return 0; bcf1_t *rec = (bcf1_t*) data; char *id; if ( col->getter ) { int nret = col->getter(args,rec,col,&col->ptr,&col->mptr); id = (char*) col->ptr; if ( nret<=0 || (nret==1 && *id=='.') ) return 0; // don't replace with "." } else { if ( rec->d.id && rec->d.id[0]=='.' && !rec->d.id[1] ) return 0; // don't replace with "." id = rec->d.id; } if ( col->replace & SET_OR_APPEND ) return bcf_add_id(args->hdr_out,line,id); if ( !(col->replace & REPLACE_MISSING) ) return bcf_update_id(args->hdr_out,line,id); // running with +ID, only update missing ids if ( !line->d.id || (line->d.id[0]=='.' && !line->d.id[1]) ) return bcf_update_id(args->hdr_out,line,id); return 0; } static int vcf_setter_ref(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; if ( !strcmp(rec->d.allele[0],line->d.allele[0]) ) return 0; // no update necessary const char **als = (const char**) malloc(sizeof(char*)*line->n_allele); als[0] = rec->d.allele[0]; int i; for (i=1; in_allele; i++) als[i] = line->d.allele[i]; int ret = bcf_update_alleles(args->hdr_out, line, als, line->n_allele); free(als); return ret; } static int vcf_setter_alt(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; int i; if ( line->n_allele>1 && (col->replace & REPLACE_MISSING) ) return 0; if ( rec->n_allele==line->n_allele ) { for (i=1; in_allele; i++) if ( strcmp(rec->d.allele[i],line->d.allele[i]) ) break; if ( i==rec->n_allele ) return 0; // no update necessary } const char **als = (const char**) malloc(sizeof(char*)*rec->n_allele); als[0] = line->d.allele[0]; for (i=1; in_allele; i++) als[i] = rec->d.allele[i]; int ret = bcf_update_alleles(args->hdr_out, line, als, rec->n_allele); free(als); return ret; } static int setter_qual(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with QUAL (yet?)\n"); annot_line_t *tab = (annot_line_t*) data; char *str = tab->cols[col->icol]; if ( str[0]=='.' && str[1]==0 ) // don't overwrite with a missing value unless asked { if ( (col->replace & CARRY_OVER_MISSING) && (col->replace & (REPLACE_ALL|REPLACE_NON_MISSING)) ) bcf_float_set_missing(line->qual); return 0; } if ( (col->replace & REPLACE_MISSING) && !bcf_float_is_missing(line->qual) ) return 0; line->qual = strtod(str, &str); if ( str == tab->cols[col->icol] ) error("Could not parse %s at %s:%"PRId64" .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1,tab->cols[col->icol]); return 0; } static int vcf_setter_qual(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; if ( bcf_float_is_missing(rec->qual) ) // don't overwrite with a missing value unless asked { if ( (col->replace & CARRY_OVER_MISSING) && (col->replace & (REPLACE_ALL|REPLACE_NON_MISSING)) ) bcf_float_set_missing(line->qual); return 0; } if ( (col->replace & REPLACE_MISSING) && !bcf_float_is_missing(line->qual) ) return 0; line->qual = rec->qual; return 0; } static int setter_info_flag(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with INFO type=Flag (yet?)\n"); annot_line_t *tab = (annot_line_t*) data; char *str = tab->cols[col->icol]; if ( str[0]=='.' && str[1]==0 ) // don't overwrite with a missing value unless asked { if ( (col->replace & CARRY_OVER_MISSING) && (col->replace & (REPLACE_ALL|REPLACE_NON_MISSING)) ) bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,0); return 0; } if ( str[0]=='1' && str[1]==0 ) return bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,1); if ( str[0]=='0' && str[1]==0 ) return bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,0); error("Could not parse %s at %s:%"PRId64" .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1,tab->cols[col->icol]); return -1; } static int vcf_setter_info_flag(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; int flag = bcf_get_info_flag(args->files->readers[1].header,rec,col->hdr_key_src,NULL,NULL); bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,flag); return 0; } static int setter_ARinfo_int32(args_t *args, bcf1_t *line, annot_col_t *col, int nals, char **als, int ntmpi) { if ( col->number==BCF_VL_A && ntmpi!=nals-1 && (ntmpi!=1 || args->tmpi[0]!=bcf_int32_missing || args->tmpi[1]!=bcf_int32_vector_end) ) error("Incorrect number of values (%d) for the %s tag at %s:%"PRId64"\n", ntmpi,col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); else if ( col->number==BCF_VL_R && ntmpi!=nals && (ntmpi!=1 || args->tmpi[0]!=bcf_int32_missing || args->tmpi[1]!=bcf_int32_vector_end) ) error("Incorrect number of values (%d) for the %s tag at %s:%"PRId64"\n", ntmpi,col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int ndst = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; int *map = vcmp_map_ARvalues(args->vcmp,ndst,nals,als,line->n_allele,line->d.allele); if ( !map ) error("REF alleles not compatible at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); // fill in any missing values in the target VCF (or all, if not present) int ntmpi2 = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpi2, &args->mtmpi2); if ( ntmpi2 < ndst ) hts_expand(int32_t,ndst,args->mtmpi2,args->tmpi2); int i; for (i=0; itmpi2[i] = bcf_int32_missing; continue; } if ( ntmpi2==ndst && (col->replace & REPLACE_MISSING) && args->tmpi2[i]!=bcf_int32_missing && args->tmpi2[i]!=bcf_int32_vector_end ) continue; args->tmpi2[i] = args->tmpi[ map[i] ]; } return bcf_update_info_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi2,ndst); } static int setter_info_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { annot_line_t *tab = (annot_line_t*) data; // This is a bit hacky, only to reuse existing code with minimal changes: // -c =TAG will now behave as -l TAG:APPEND for integers if ( col->replace & SET_OR_APPEND ) col->merge_method=MM_APPEND; if ( !tab ) { if ( col->merge_method!=MM_SUM && col->merge_method!=MM_AVG && col->merge_method!=MM_MIN && col->merge_method!=MM_MAX && col->merge_method!=MM_APPEND && col->merge_method!=MM_APPEND_MISSING ) error("Error: at the moment only the sum,avg,min,max,append,append-missing options are supported with --merge-logic for INFO type=Integer\n"); } int i,ntmpi = 0; if ( (col->replace & SET_OR_APPEND) && !col->mm_dbl_nused ) { ntmpi = bcf_get_info_int32(args->hdr, line, col->hdr_key_dst, &args->tmpi, &args->mtmpi); if ( ntmpi>0 && (args->tmpi[0]!=bcf_int32_missing || (col->replace & CARRY_OVER_MISSING)) ) { col->mm_dbl_nused = col->mm_dbl_ndat = ntmpi; hts_expand(double,col->mm_dbl_nused,col->mm_dbl_nalloc,col->mm_dbl); for (i=0; imm_dbl[i] = args->tmpi[i]; col->mm_dbl_ndat = 1; } ntmpi = 0; } if ( tab ) // has data, not flushing yet { char *str = tab->cols[col->icol], *end = str; if ( str[0]=='.' && str[1]==0 && col->merge_method!=MM_APPEND_MISSING && !(col->replace & CARRY_OVER_MISSING) ) return 1; while ( *end ) { ntmpi++; hts_expand(int32_t,ntmpi,args->mtmpi,args->tmpi); if ( str[0]=='.' && (str[1]==0 || str[1]==',') ) { if ( col->merge_method==MM_APPEND_MISSING || (col->replace & CARRY_OVER_MISSING) ) args->tmpi[ntmpi-1] = bcf_int32_missing; else ntmpi--; if ( str[1]==0 ) end = str+1; str += 2; } else { args->tmpi[ntmpi-1] = strtol(str, &end, 10); if ( end==str ) error("Could not parse %s at %s:%"PRId64" .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1,tab->cols[col->icol]); str = end+1; } } if ( col->merge_method!=MM_FIRST ) { if ( !col->mm_dbl_nused ) { col->mm_dbl_nused = ntmpi; hts_expand(double,col->mm_dbl_nused,col->mm_dbl_nalloc,col->mm_dbl); for (i=0; imm_dbl[i] = args->tmpi[i]; } else { if ( col->merge_method==MM_APPEND || col->merge_method==MM_APPEND_MISSING ) { int nori = col->mm_dbl_nused; col->mm_dbl_nused += ntmpi; hts_expand(double,col->mm_dbl_nused,col->mm_dbl_nalloc,col->mm_dbl); for (i=0; imm_dbl[i+nori] = args->tmpi[i]; } else { if ( ntmpi!=col->mm_dbl_nused ) error("Error: cannot merge fields of unequal length\n"); if ( col->merge_method==MM_SUM || col->merge_method==MM_AVG ) for (i=0; imm_dbl[i] += args->tmpi[i]; else if ( col->merge_method==MM_MIN ) for (i=0; imm_dbl[i] > args->tmpi[i] ) col->mm_dbl[i] = args->tmpi[i]; } else if ( col->merge_method==MM_MAX ) for (i=0; imm_dbl[i] < args->tmpi[i] ) col->mm_dbl[i] = args->tmpi[i]; } } } col->mm_dbl_ndat++; return 1; } } else if ( col->merge_method==MM_SUM || col->merge_method==MM_MIN || col->merge_method==MM_MAX || col->merge_method==MM_APPEND || col->merge_method==MM_APPEND_MISSING ) { ntmpi = col->mm_dbl_nused; hts_expand(int32_t,ntmpi,args->mtmpi,args->tmpi); for (i=0; itmpi[i] = col->mm_dbl[i]; col->mm_dbl_nused = col->mm_dbl_ndat = 0; } else if ( col->merge_method==MM_AVG ) { ntmpi = col->mm_dbl_nused; hts_expand(int32_t,ntmpi,args->mtmpi,args->tmpi); for (i=0; itmpi[i] = col->mm_dbl[i]/col->mm_dbl_ndat; col->mm_dbl_nused = col->mm_dbl_ndat = 0; } if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) return setter_ARinfo_int32(args,line,col,tab->nals,tab->als,ntmpi); if ( col->replace & REPLACE_MISSING ) { int ret = bcf_get_info_int32(args->hdr, line, col->hdr_key_dst, &args->tmpi2, &args->mtmpi2); if ( ret>0 && args->tmpi2[0]!=bcf_int32_missing ) return 0; } return bcf_update_info_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi,ntmpi); } static int vcf_setter_info_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; int ntmpi = bcf_get_info_int32(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpi,&args->mtmpi); if ( ntmpi < 0 ) return 0; // nothing to add if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) return setter_ARinfo_int32(args,line,col,rec->n_allele,rec->d.allele,ntmpi); if ( col->replace & REPLACE_MISSING ) { int ret = bcf_get_info_int32(args->hdr, line, col->hdr_key_dst, &args->tmpi2, &args->mtmpi2); if ( ret>0 && args->tmpi2[0]!=bcf_int32_missing ) return 0; } return bcf_update_info_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi,ntmpi); } static int setter_ARinfo_real(args_t *args, bcf1_t *line, annot_col_t *col, int nals, char **als, int ntmpf) { if ( col->number==BCF_VL_A && ntmpf!=nals-1 && (ntmpf!=1 || !bcf_float_is_missing(args->tmpf[0]) || !bcf_float_is_vector_end(args->tmpf[0])) ) error("Incorrect number of values (%d) for the %s tag at %s:%"PRId64"\n", ntmpf,col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); else if ( col->number==BCF_VL_R && ntmpf!=nals && (ntmpf!=1 || !bcf_float_is_missing(args->tmpf[0]) || !bcf_float_is_vector_end(args->tmpf[0])) ) error("Incorrect number of values (%d) for the %s tag at %s:%"PRId64"\n", ntmpf,col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int ndst = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; int *map = vcmp_map_ARvalues(args->vcmp,ndst,nals,als,line->n_allele,line->d.allele); if ( !map ) error("REF alleles not compatible at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); // fill in any missing values in the target VCF (or all, if not present) int ntmpf2 = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf2, &args->mtmpf2); if ( ntmpf2 < ndst ) hts_expand(float,ndst,args->mtmpf2,args->tmpf2); int i; for (i=0; itmpf2[i]); continue; } if ( ntmpf2==ndst && (col->replace & REPLACE_MISSING) && !bcf_float_is_missing(args->tmpf2[i]) && !bcf_float_is_vector_end(args->tmpf2[i]) ) continue; args->tmpf2[i] = args->tmpf[ map[i] ]; } return bcf_update_info_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf2,ndst); } static int setter_info_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { annot_line_t *tab = (annot_line_t*) data; // This is a bit hacky, only to reuse existing code with minimal changes: // -c =TAG will now behave as -l TAG:APPEND for floats if ( col->replace & SET_OR_APPEND ) col->merge_method=MM_APPEND; if ( !tab ) { if ( col->merge_method!=MM_SUM && col->merge_method!=MM_AVG && col->merge_method!=MM_MIN && col->merge_method!=MM_MAX && col->merge_method!=MM_APPEND && col->merge_method!=MM_APPEND_MISSING ) error("Error: at the moment only the sum,avg,min,max,append,append-missing options are supported with --merge-logic for INFO type=Float\n"); } int i,ntmpf = 0; if ( (col->replace & SET_OR_APPEND) && !col->mm_dbl_nused ) { ntmpf = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf, &args->mtmpf); if ( ntmpf>0 && (!bcf_float_is_missing(args->tmpf[0]) || (col->replace & CARRY_OVER_MISSING)) ) { col->mm_dbl_nused = ntmpf; hts_expand(double,col->mm_dbl_nused,col->mm_dbl_nalloc,col->mm_dbl); for (i=0; itmpf[i]) ) bcf_double_set_missing(col->mm_dbl[i]); else col->mm_dbl[i] = args->tmpf[i]; col->mm_dbl_ndat = 1; } ntmpf = 0; } if ( tab ) // data row, not just flushing { char *str = tab->cols[col->icol], *end = str; if ( str[0]=='.' && str[1]==0 && col->merge_method!=MM_APPEND_MISSING && !(col->replace & CARRY_OVER_MISSING) ) return 1; while ( *end ) { ntmpf++; hts_expand(float,ntmpf,args->mtmpf,args->tmpf); if ( str[0]=='.' && (str[1]==0 || str[1]==',') ) { if ( col->merge_method==MM_APPEND_MISSING || (col->replace & CARRY_OVER_MISSING) ) bcf_float_set_missing(args->tmpf[ntmpf-1]); else ntmpf--; if ( str[1]==0 ) end = str+1; str += 2; } else { args->tmpf[ntmpf-1] = strtod(str, &end); if ( end==str ) error("Could not parse %s at %s:%"PRId64" .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1,tab->cols[col->icol]); str = end+1; } } if ( col->merge_method!=MM_FIRST ) { if ( !col->mm_dbl_nused ) { col->mm_dbl_nused = ntmpf; hts_expand(double,col->mm_dbl_nused,col->mm_dbl_nalloc,col->mm_dbl); for (i=0; itmpf[i]) ) bcf_double_set_missing(col->mm_dbl[i]); else col->mm_dbl[i] = args->tmpf[i]; } } else { if ( col->merge_method==MM_APPEND || col->merge_method==MM_APPEND_MISSING ) { int nori = col->mm_dbl_nused; col->mm_dbl_nused += ntmpf; hts_expand(double,col->mm_dbl_nused,col->mm_dbl_nalloc,col->mm_dbl); for (i=0; itmpf[i]) ) bcf_double_set_missing(col->mm_dbl[i+nori]); else col->mm_dbl[i+nori] = args->tmpf[i]; } } else { if ( ntmpf!=col->mm_dbl_nused ) error("Error: cannot merge fields of unequal length\n"); if ( col->merge_method==MM_SUM || col->merge_method==MM_AVG ) for (i=0; imm_dbl[i] += args->tmpf[i]; else if ( col->merge_method==MM_MIN ) for (i=0; imm_dbl[i] > args->tmpf[i] ) col->mm_dbl[i] = args->tmpf[i]; } else if ( col->merge_method==MM_MAX ) for (i=0; imm_dbl[i] < args->tmpf[i] ) col->mm_dbl[i] = args->tmpf[i]; } } } col->mm_dbl_ndat++; return 1; } } else if ( col->merge_method==MM_SUM || col->merge_method==MM_MIN || col->merge_method==MM_MAX || col->merge_method==MM_APPEND || col->merge_method==MM_APPEND_MISSING ) { ntmpf = col->mm_dbl_nused; hts_expand(int32_t,ntmpf,args->mtmpf,args->tmpf); for (i=0; imm_dbl[i]) ) bcf_float_set_missing(args->tmpf[i]); else args->tmpf[i] = col->mm_dbl[i]; } col->mm_dbl_nused = col->mm_dbl_ndat = 0; } else if ( col->merge_method==MM_AVG ) { ntmpf = col->mm_dbl_nused; hts_expand(int32_t,ntmpf,args->mtmpf,args->tmpf); for (i=0; itmpf[i] = col->mm_dbl[i]/col->mm_dbl_ndat; col->mm_dbl_nused = col->mm_dbl_ndat = 0; } if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) return setter_ARinfo_real(args,line,col,tab->nals,tab->als,ntmpf); if ( col->replace & REPLACE_MISSING ) { int ret = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf2, &args->mtmpf2); if ( ret>0 && !bcf_float_is_missing(args->tmpf2[0]) ) return 0; } return bcf_update_info_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf,ntmpf); } static int vcf_setter_info_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; int ntmpf = bcf_get_info_float(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpf,&args->mtmpf); if ( ntmpf < 0 ) return 0; // nothing to add if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) return setter_ARinfo_real(args,line,col,rec->n_allele,rec->d.allele,ntmpf); if ( col->replace & REPLACE_MISSING ) { int ret = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf2, &args->mtmpf2); if ( ret>0 && !bcf_float_is_missing(args->tmpf2[0]) ) return 0; } return bcf_update_info_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf,ntmpf); } int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst); // see vcfmerge.c static int setter_ARinfo_string(args_t *args, bcf1_t *line, annot_col_t *col, int nals, char **als) { assert( col->merge_method==MM_FIRST ); int nsrc = 1, lsrc = 0; while ( args->tmps[lsrc] ) { if ( args->tmps[lsrc]==',' ) nsrc++; lsrc++; } if ( col->number==BCF_VL_A && nsrc!=nals-1 && (nsrc!=1 || args->tmps[0]!='.' || args->tmps[1]!=0 ) ) error("Incorrect number of values (%d) for the %s tag at %s:%"PRId64"\n", nsrc,col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); else if ( col->number==BCF_VL_R && nsrc!=nals && (nsrc!=1 || args->tmps[0]!='.' || args->tmps[1]!=0 ) ) error("Incorrect number of values (%d) for the %s tag at %s:%"PRId64"\n", nsrc,col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int ndst = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; int *map = vcmp_map_ARvalues(args->vcmp,ndst,nals,als,line->n_allele,line->d.allele); if ( !map ) error("REF alleles not compatible at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); // fill in any missing values in the target VCF (or all, if not present) int i, empty = 0, nstr, mstr = args->tmpks.m; nstr = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &args->tmpks.s, &mstr); args->tmpks.m = mstr; if ( nstr<0 || (nstr==1 && args->tmpks.s[0]=='.' && args->tmpks.s[1]==0) ) { empty = 0; args->tmpks.l = 0; kputc('.',&args->tmpks); for (i=1; itmpks); } else args->tmpks.l = nstr; for (i=0; itmpks,i); continue; } if ( col->replace & REPLACE_MISSING ) { // Do not replace filled values. The field must be looked up again because // of realloc in copy_string_field int n = 0; char *str = args->tmpks.s; while ( *str && ntmps,map[i],lsrc,&args->tmpks,i); if ( ret!=0 ) error("[%s:%d %s] Failed to copy a string field\n", __FILE__,__LINE__,__func__); } return bcf_update_info_string(args->hdr_out,line,col->hdr_key_dst,args->tmpks.s); } void khash_str2int_clear_free(void *_hash) { khash_t(str2int) *hash = (khash_t(str2int)*)_hash; khint_t k; if (hash == 0) return; for (k = 0; k < kh_end(hash); ++k) if (kh_exist(hash, k)) free((char*)kh_key(hash, k)); kh_clear(str2int, hash); } static const char *escape_string(const char *str, char needle[], char **rmme, size_t *len) { kstring_t tmp = {0,0,0}; const char *bp = str, *ep = str; while ( *ep ) { int i = 0; while ( needle[i] && needle[i]!=*ep ) i++; if ( !needle[i] ) { ep++; continue; } kputsn(bp,ep-bp,&tmp); ksprintf(&tmp,"%%%X",*ep); bp = ++ep; } if ( !tmp.l ) { *len = strlen(str); return str; } kputs(bp,&tmp); *len = tmp.l; *rmme = tmp.s; return tmp.s; } static int setter_info_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( (col->replace & REPLACE_MISSING) && col->number!=BCF_VL_A && col->number!=BCF_VL_R ) { int ret = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &args->tmps2, &args->mtmps2); if ( ret>0 && (args->tmps2[0]!='.' || args->tmps2[1]!=0) ) return 0; } // This is a bit hacky, only to reuse existing code with minimal changes: // -c =TAG will now behave as -l TAG:unique for strings if ( col->replace & SET_OR_APPEND ) col->merge_method=MM_UNIQUE; annot_line_t *tab = (annot_line_t*) data; const char *escaped = NULL; char *rmme = NULL; size_t len = 0; if ( tab ) { char *str = tab->cols[col->icol]; if ( !str || !*str ) return 0; if ( !str[1] && str[0]=='.' && col->merge_method!=MM_APPEND_MISSING && !(col->replace & CARRY_OVER_MISSING) ) return 1; char needle[] = {';','=',0}; escaped = escape_string(tab->cols[col->icol],needle,&rmme,&len); } if ( col->merge_method!=MM_FIRST ) { if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) error("Error: the --merge-logic option cannot be used with INFO tags Type=String,Number={A,R,G}\n"); if ( data ) { assert( col->merge_method==MM_APPEND || col->merge_method==MM_APPEND_MISSING || col->merge_method==MM_UNIQUE ); if ( col->merge_method==MM_UNIQUE ) { if ( !col->mm_str_hash ) col->mm_str_hash = (khash_t(str2int)*)khash_str2int_init(); if ( khash_str2int_has_key(col->mm_str_hash, escaped) ) { free(rmme); return 1; } khash_str2int_inc(col->mm_str_hash, strdup(escaped)); } if ( (col->replace & SET_OR_APPEND) && !col->mm_kstr.l ) { int m = col->mm_kstr.m; int n = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &col->mm_kstr.s, &m); col->mm_kstr.m = m; if ( n>0 && ((col->replace & CARRY_OVER_MISSING) || col->mm_kstr.s[0]!='.' || col->mm_kstr.s[1]) ) col->mm_kstr.l = n; } if ( col->mm_kstr.l ) kputc(',',&col->mm_kstr); kputs(escaped, &col->mm_kstr); free(rmme); return 1; } if ( col->mm_kstr.l ) { hts_expand(char,col->mm_kstr.l+1,args->mtmps,args->tmps); memcpy(args->tmps,col->mm_kstr.s,col->mm_kstr.l+1); } else { free(rmme); return 0; } // flush the line if ( col->merge_method==MM_UNIQUE ) khash_str2int_clear_free(col->mm_str_hash); col->mm_kstr.l = 0; } else { assert(tab); hts_expand(char,len+1,args->mtmps,args->tmps); memcpy(args->tmps,escaped,len+1); if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) return setter_ARinfo_string(args,line,col,tab->nals,tab->als); } int ret = bcf_update_info_string(args->hdr_out,line,col->hdr_key_dst,args->tmps); free(rmme); return ret; } static int vcf_setter_info_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; if ( col->getter ) col->getter(args,rec,col,(void**)&args->tmps, &args->mtmps); else { int ntmps = bcf_get_info_string(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmps,&args->mtmps); if ( ntmps < 0 ) return 0; // nothing to add } if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) return setter_ARinfo_string(args,line,col,rec->n_allele,rec->d.allele); if ( col->replace & REPLACE_MISSING ) { int ret = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &args->tmps2, &args->mtmps2); if ( ret>0 && (args->tmps2[0]!='.' || args->tmps2[1]!=0) ) return 0; } return bcf_update_info_string(args->hdr_out,line,col->hdr_key_dst,args->tmps); } static int genotypes_to_string(args_t *args, int nsrc1, int32_t *src, int nsmpl_dst, kstring_t *str) { int i, isrc, idst; int blen = nsrc1 > 1 ? nsrc1 + 1 : 1; // typically the genotypes take three bytes 0/1, no 0-termination is needed gt_length_too_big: str->l = 0; for (idst=0; idstsample_map ? args->sample_map[idst] : idst; if ( isrc==-1 ) { kputc_('.', str); for (i=1; i < blen; i++) kputc_(0, str); continue; } size_t plen = str->l; int32_t *ptr = src + isrc*nsrc1; for (i=0; il - plen > blen ) { // too many alternate alleles or ploidy is too large, the genotype does not fit // three characters ("0/0" vs "10/10"). blen *= 2; goto gt_length_too_big; } plen = str->l - plen; while ( plen < blen ) { kputc_(0, str); plen++; } } return 0; } static int vcf_setter_format_gt(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; int nsrc = bcf_get_genotypes(args->files->readers[1].header,rec,&args->tmpi,&args->mtmpi); if ( nsrc==-3 ) return 0; // the tag is not present if ( nsrc<=0 ) return 1; // error // Genotypes are internally represented as integers. This is a complication when // adding as a different Type=String field, such as FMT/newGT:=GT if ( strcmp(col->hdr_key_src,col->hdr_key_dst) ) { int nsmpl_dst = bcf_hdr_nsamples(args->hdr_out); int nsmpl_src = bcf_hdr_nsamples(args->files->readers[1].header); genotypes_to_string(args,nsrc/nsmpl_src,args->tmpi,nsmpl_dst,&args->tmpks); return bcf_update_format_char(args->hdr_out,line,col->hdr_key_dst,args->tmpks.s,args->tmpks.l); } if ( !args->sample_map ) return bcf_update_genotypes(args->hdr_out,line,args->tmpi,nsrc); int i, j, ndst = bcf_get_genotypes(args->hdr,line,&args->tmpi2,&args->mtmpi2); if ( ndst > 0 ) ndst /= bcf_hdr_nsamples(args->hdr_out); nsrc /= bcf_hdr_nsamples(args->files->readers[1].header); if ( ndst<=0 ) // field not present in dst file { if ( col->replace & REPLACE_NON_MISSING ) return 0; hts_expand(int32_t, nsrc*bcf_hdr_nsamples(args->hdr_out), args->mtmpi2, args->tmpi2); for (i=0; ihdr_out); i++) { int32_t *dst = args->tmpi2 + nsrc*i; if ( args->sample_map[i]==-1 ) { dst[0] = bcf_gt_missing; for (j=1; jtmpi + nsrc*args->sample_map[i]; for (j=0; jhdr_out,line,args->tmpi2,nsrc*bcf_hdr_nsamples(args->hdr_out)); } else if ( ndst >= nsrc ) { for (i=0; ihdr_out); i++) { if ( args->sample_map[i]==-1 ) continue; int32_t *src = args->tmpi + nsrc*args->sample_map[i]; int32_t *dst = args->tmpi2 + ndst*i; if ( (col->replace & REPLACE_NON_MISSING) && bcf_gt_is_missing(dst[0]) ) continue; if ( (col->replace & REPLACE_MISSING) && !bcf_gt_is_missing(dst[0]) ) continue; for (j=0; jhdr_out,line,args->tmpi2,ndst*bcf_hdr_nsamples(args->hdr_out)); } else // ndst < nsrc { hts_expand(int32_t, nsrc*bcf_hdr_nsamples(args->hdr_out), args->mtmpi3, args->tmpi3); for (i=0; ihdr_out); i++) { int32_t *ori = args->tmpi2 + ndst*i; int32_t *dst = args->tmpi3 + nsrc*i; int keep_ori = 0; if ( args->sample_map[i]==-1 ) keep_ori = 1; else if ( (col->replace & REPLACE_NON_MISSING) && bcf_gt_is_missing(ori[0]) ) keep_ori = 1; else if ( (col->replace & REPLACE_MISSING) && !bcf_gt_is_missing(ori[0]) ) keep_ori = 1; if ( keep_ori ) { for (j=0; jtmpi + nsrc*args->sample_map[i]; for (j=0; jhdr_out,line,args->tmpi3,nsrc*bcf_hdr_nsamples(args->hdr_out)); } } static int count_vals(annot_line_t *tab, int icol_beg, int icol_end) { int i, nmax = 1; for (i=icol_beg; icols[i], *end = str; if ( str[0]=='.' && !str[1] ) { // missing value if ( !nmax ) nmax = 1; continue; } int n = 1; while ( *end ) { if ( *end==',' ) n++; end++; } if ( nmaxsample_map ) return bcf_update_format_int32(args->hdr_out,line,col->hdr_key_dst,vals,nvals*args->nsmpl_annot); int i, j, ndst = bcf_get_format_int32(args->hdr,line,col->hdr_key_dst,&args->tmpi2,&args->mtmpi2); if ( ndst > 0 ) ndst /= bcf_hdr_nsamples(args->hdr_out); if ( ndst<=0 ) { if ( col->replace & REPLACE_NON_MISSING ) return 0; // overwrite only if present hts_expand(int32_t, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpi2, args->tmpi2); for (i=0; ihdr_out); i++) { int32_t *dst = args->tmpi2 + nvals*i; if ( args->sample_map[i]==-1 ) { dst[0] = bcf_int32_missing; for (j=1; jsample_map[i]; for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpi2,nvals*bcf_hdr_nsamples(args->hdr_out)); } else if ( ndst >= nvals ) { for (i=0; ihdr_out); i++) { if ( args->sample_map[i]==-1 ) continue; int32_t *src = vals + nvals*args->sample_map[i]; int32_t *dst = args->tmpi2 + ndst*i; // possible cases: // in annot out // x y x TAG,-TAG,=TAG .. REPLACE_ALL, REPLACE_NON_MISSING, SET_OR_APPEND // x y y +TAG .. REPLACE_MISSING // . y . =TAG .. SET_OR_APPEND // . y y TAG,+TAG,-TAG .. REPLACE_ALL, REPLACE_MISSING, REPLACE_NON_MISSING // x . x TAG,+TAG .. REPLACE_ALL, REPLACE_MISSING // x . . -TAG .. REPLACE_NON_MISSING if ( col->replace & REPLACE_NON_MISSING ) { if ( dst[0]==bcf_int32_missing ) continue; } else if ( col->replace & REPLACE_MISSING ) { if ( dst[0]!=bcf_int32_missing ) continue; } else if ( col->replace & REPLACE_ALL ) { if ( src[0]==bcf_int32_missing ) continue; } for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpi2,ndst*bcf_hdr_nsamples(args->hdr_out)); } else // ndst < nvals { hts_expand(int32_t, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpi3, args->tmpi3); for (i=0; ihdr_out); i++) { int32_t *ann = vals + nvals*args->sample_map[i]; int32_t *ori = args->tmpi2 + ndst*i; // ori vcf line int32_t *dst = args->tmpi3 + nvals*i; // expanded buffer int use_new_ann = 1; if ( args->sample_map[i]==-1 ) use_new_ann = 0; else if ( col->replace & REPLACE_NON_MISSING ) { if ( ori[0]==bcf_int32_missing ) use_new_ann = 0; } else if ( col->replace & REPLACE_MISSING ) { if ( ori[0]!=bcf_int32_missing ) use_new_ann = 0; } else if ( col->replace & REPLACE_ALL ) { if ( ann[0]==bcf_int32_missing ) use_new_ann = 0; } if ( !use_new_ann ) { for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpi3,nvals*bcf_hdr_nsamples(args->hdr_out)); } } static int core_setter_format_real(args_t *args, bcf1_t *line, annot_col_t *col, float *vals, int nvals) { if ( !args->sample_map ) return bcf_update_format_float(args->hdr_out,line,col->hdr_key_dst,vals,nvals*args->nsmpl_annot); int i, j, ndst = bcf_get_format_float(args->hdr,line,col->hdr_key_dst,&args->tmpf2,&args->mtmpf2); if ( ndst > 0 ) ndst /= bcf_hdr_nsamples(args->hdr_out); if ( ndst<=0 ) { if ( col->replace & REPLACE_NON_MISSING ) return 0; // overwrite only if present hts_expand(float, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpf2, args->tmpf2); for (i=0; ihdr_out); i++) { float *dst = args->tmpf2 + nvals*i; if ( args->sample_map[i]==-1 ) { bcf_float_set_missing(dst[0]); for (j=1; jsample_map[i]; for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpf2,nvals*bcf_hdr_nsamples(args->hdr_out)); } else if ( ndst >= nvals ) { for (i=0; ihdr_out); i++) { if ( args->sample_map[i]==-1 ) continue; float *src = vals + nvals*args->sample_map[i]; float *dst = args->tmpf2 + ndst*i; if ( col->replace & REPLACE_NON_MISSING ) { if ( bcf_float_is_missing(dst[0]) ) continue; } else if ( col->replace & REPLACE_MISSING ) { if ( !bcf_float_is_missing(dst[0]) ) continue; } else if ( col->replace & REPLACE_ALL ) { if ( bcf_float_is_missing(src[0]) ) continue; } for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpf2,ndst*bcf_hdr_nsamples(args->hdr_out)); } else // ndst < nvals { hts_expand(float, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpf3, args->tmpf3); for (i=0; ihdr_out); i++) { float *ann = vals + nvals*args->sample_map[i]; float *ori = args->tmpf2 + ndst*i; // ori vcf line float *dst = args->tmpf3 + nvals*i; // expanded buffer int use_new_ann = 1; if ( args->sample_map[i]==-1 ) use_new_ann = 0; else if ( col->replace & REPLACE_NON_MISSING ) { if ( bcf_float_is_missing(ori[0]) ) use_new_ann = 0; } else if ( col->replace & REPLACE_MISSING ) { if ( !bcf_float_is_missing(ori[0]) ) use_new_ann = 0; } else if ( col->replace & REPLACE_ALL ) { if ( bcf_float_is_missing(ann[0]) ) use_new_ann = 0; } if ( !use_new_ann ) { for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpf3,nvals*bcf_hdr_nsamples(args->hdr_out)); } } static int core_setter_format_str(args_t *args, bcf1_t *line, annot_col_t *col, char **vals) { if ( !args->sample_map ) return bcf_update_format_string(args->hdr_out,line,col->hdr_key_dst,(const char**)vals,args->nsmpl_annot); int i; args->tmpp2[0] = args->tmps2; int ret = bcf_get_format_string(args->hdr,line,col->hdr_key_dst,&args->tmpp2,&args->mtmps2); args->tmps2 = args->tmpp2[0]; // tmps2 might be realloced int nsmpl = bcf_hdr_nsamples(args->hdr_out); if ( ret<=0 ) // not present in dst { hts_expand(char,bcf_hdr_nsamples(args->hdr_out)*2,args->mtmps2,args->tmps2); char *tmp = args->tmps2; for (i=0; itmpp2[i] = tmp; tmp += 2; } } for (i=0; isample_map[i]==-1 ) continue; char **src = vals + args->sample_map[i]; char **dst = args->tmpp2 + i; if ( col->replace & REPLACE_NON_MISSING ) { if ( (*dst)[0]=='.' && (*dst)[1]==0 ) continue; } else if ( col->replace & REPLACE_MISSING ) { if ( (*dst)[0]!='.' || (*dst)[1]!=0 ) continue; } else if ( col->replace & REPLACE_ALL ) { if ( (*src)[0]=='.' && (*src)[1]==0 ) continue; } *dst = *src; } return bcf_update_format_string(args->hdr_out,line,col->hdr_key_dst,(const char**)args->tmpp2,nsmpl); } static int setter_format_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with FORMAT tags (yet?)\n"); annot_line_t *tab = (annot_line_t*) data; if ( col->icol+args->nsmpl_annot > tab->ncols ) error("Incorrect number of values for %s at %s:%"PRId64"\n",col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int nvals = count_vals(tab,col->icol,col->icol+args->nsmpl_annot); hts_expand(int32_t,nvals*args->nsmpl_annot,args->mtmpi,args->tmpi); int icol = col->icol, ismpl; for (ismpl=0; ismplnsmpl_annot; ismpl++) { int32_t *ptr = args->tmpi + ismpl*nvals; int ival = 0; char *str = tab->cols[icol]; while ( *str ) { if ( str[0]=='.' && (!str[1] || str[1]==',') ) // missing value { ptr[ival++] = bcf_int32_missing; str += str[1] ? 2 : 1; continue; } char *end = str; ptr[ival] = strtol(str, &end, 10); if ( end==str ) error("Could not parse %s at %s:%"PRId64" .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1,tab->cols[col->icol]); ival++; str = *end ? end+1 : end; } while ( ivaltmpi,nvals); } static int setter_format_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with FORMAT tags (yet?)\n"); annot_line_t *tab = (annot_line_t*) data; if ( col->icol+args->nsmpl_annot > tab->ncols ) error("Incorrect number of values for %s at %s:%"PRId64"\n",col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int nvals = count_vals(tab,col->icol,col->icol+args->nsmpl_annot); hts_expand(float,nvals*args->nsmpl_annot,args->mtmpf,args->tmpf); int icol = col->icol, ismpl; for (ismpl=0; ismplnsmpl_annot; ismpl++) { float *ptr = args->tmpf + ismpl*nvals; int ival = 0; char *str = tab->cols[icol]; while ( *str ) { if ( str[0]=='.' && (!str[1] || str[1]==',') ) // missing value { bcf_float_set_missing(ptr[ival]); ival++; str += str[1] ? 2 : 1; continue; } char *end = str; ptr[ival] = strtod(str, &end); if ( end==str ) error("Could not parse %s at %s:%"PRId64" .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1,tab->cols[col->icol]); ival++; str = *end ? end+1 : end; } while ( ivaltmpf,nvals); } static int setter_format_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { if ( !data ) error("Error: the --merge-logic option cannot be used with FORMAT tags (yet?)\n"); annot_line_t *tab = (annot_line_t*) data; if ( col->icol+args->nsmpl_annot > tab->ncols ) error("Incorrect number of values for %s at %s:%"PRId64"\n",col->hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); char needle[] = {':',0}; int ismpl; for (ismpl=0; ismplnsmpl_annot; ismpl++) { size_t len; char *rmme = NULL; const char *str = escape_string(tab->cols[col->icol + ismpl],needle,&rmme,&len); args->tmpp[ismpl] = rmme ? rmme : strdup(str); } int ret = core_setter_format_str(args,line,col,args->tmpp); for (ismpl=0; ismplnsmpl_annot; ismpl++) free(args->tmpp[ismpl]); return ret; } static int determine_ploidy(int nals, int *vals, int nvals1, uint8_t *smpl, int nsmpl) { int i, j, ndip = nals*(nals+1)/2, max_ploidy = 0; for (i=0; ifiles->readers[1].header,rec,col->hdr_key_src,&args->tmpi,&args->mtmpi); if ( nsrc==-3 ) return 0; // the tag is not present if ( nsrc<=0 ) return 1; // error int nsmpl_src = bcf_hdr_nsamples(args->files->readers[1].header); int nsrc1 = nsrc / nsmpl_src; if ( col->number!=BCF_VL_G && col->number!=BCF_VL_R && col->number!=BCF_VL_A ) return core_setter_format_int(args,line,col,args->tmpi,nsrc1); // create mapping from src to dst genotypes, haploid and diploid version int nmap_hap = col->number==BCF_VL_G || col->number==BCF_VL_R ? rec->n_allele : rec->n_allele - 1; int *map_hap = vcmp_map_ARvalues(args->vcmp,nmap_hap,line->n_allele,line->d.allele,rec->n_allele,rec->d.allele); if ( !map_hap ) error("REF alleles not compatible at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int i, j; if ( rec->n_allele==line->n_allele ) { // alleles unchanged? for (i=0; in_allele; i++) if ( map_hap[i]!=i ) break; if ( i==rec->n_allele ) return core_setter_format_int(args,line,col,args->tmpi,nsrc1); } int nsmpl_dst = rec->n_sample; int ndst = bcf_get_format_int32(args->hdr,line,col->hdr_key_dst,&args->tmpi2,&args->mtmpi2); int ndst1 = ndst / nsmpl_dst; if ( ndst <= 0 ) { if ( col->replace & REPLACE_NON_MISSING ) return 0; // overwrite only if present if ( col->number==BCF_VL_G ) ndst1 = line->n_allele*(line->n_allele+1)/2; else ndst1 = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; hts_expand(int, ndst1*nsmpl_dst, args->mtmpi2, args->tmpi2); for (i=0; itmpi2 + i*ndst1; for (j=0; jnumber==BCF_VL_G ) { map_dip = vcmp_map_dipGvalues(args->vcmp, &nmap_dip); if ( !args->src_smpl_pld ) { args->src_smpl_pld = (uint8_t*) malloc(nsmpl_src); args->dst_smpl_pld = (uint8_t*) malloc(nsmpl_dst); } int pld_src = determine_ploidy(rec->n_allele, args->tmpi, nsrc1, args->src_smpl_pld, nsmpl_src); if ( pld_src<0 ) error("Unexpected number of %s values (%d) for %d alleles at %s:%"PRId64"\n", col->hdr_key_src,-pld_src, rec->n_allele, bcf_seqname(bcf_sr_get_header(args->files,1),rec),(int64_t) rec->pos+1); int pld_dst = determine_ploidy(line->n_allele, args->tmpi2, ndst1, args->dst_smpl_pld, nsmpl_dst); if ( pld_dst<0 ) error("Unexpected number of %s values (%d) for %d alleles at %s:%"PRId64"\n", col->hdr_key_src,-pld_dst, line->n_allele, bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int ndst1_new = pld_dst==1 ? line->n_allele : line->n_allele*(line->n_allele+1)/2; if ( ndst1_new != ndst1 ) { if ( ndst1 ) error("todo: %s ndst1!=ndst .. %d %d at %s:%"PRId64"\n",col->hdr_key_src,ndst1_new,ndst1,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); ndst1 = ndst1_new; hts_expand(int32_t, ndst1*nsmpl_dst, args->mtmpi2, args->tmpi2); } } else if ( !ndst1 ) { ndst1 = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; hts_expand(int32_t, ndst1*nsmpl_dst, args->mtmpi2, args->tmpi2); } for (i=0; isample_map ? args->sample_map[i] : i; int32_t *ptr_src = args->tmpi + i*nsrc1; int32_t *ptr_dst = args->tmpi2 + ii*ndst1; if ( col->number==BCF_VL_G ) { if ( args->src_smpl_pld[ii] > 0 && args->dst_smpl_pld[i] > 0 && args->src_smpl_pld[ii]!=args->dst_smpl_pld[i] ) error("Sample ploidy differs at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); if ( !args->dst_smpl_pld[i] ) for (j=0; jnumber!=BCF_VL_G || args->src_smpl_pld[i]==1 ) { for (j=0; j=0 ) ptr_dst[k] = ptr_src[j]; } if ( col->number==BCF_VL_G ) for (j=line->n_allele; j=0 ) ptr_dst[k] = ptr_src[j]; } } } return bcf_update_format_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi2,nsmpl_dst*ndst1); } static int vcf_setter_format_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; int nsrc = bcf_get_format_float(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpf,&args->mtmpf); if ( nsrc==-3 ) return 0; // the tag is not present if ( nsrc<=0 ) return 1; // error int nsmpl_src = bcf_hdr_nsamples(args->files->readers[1].header); int nsrc1 = nsrc / nsmpl_src; if ( col->number!=BCF_VL_G && col->number!=BCF_VL_R && col->number!=BCF_VL_A ) return core_setter_format_real(args,line,col,args->tmpf,nsrc1); // create mapping from src to dst genotypes, haploid and diploid version int nmap_hap = col->number==BCF_VL_G || col->number==BCF_VL_R ? rec->n_allele : rec->n_allele - 1; int *map_hap = vcmp_map_ARvalues(args->vcmp,nmap_hap,line->n_allele,line->d.allele,rec->n_allele,rec->d.allele); if ( !map_hap ) error("REF alleles not compatible at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int i, j; if ( rec->n_allele==line->n_allele ) { // alleles unchanged? for (i=0; in_allele; i++) if ( map_hap[i]!=i ) break; if ( i==rec->n_allele ) return core_setter_format_real(args,line,col,args->tmpf,nsrc1); } int nsmpl_dst = rec->n_sample; int ndst = bcf_get_format_float(args->hdr,line,col->hdr_key_dst,&args->tmpf2,&args->mtmpf2); int ndst1 = ndst / nsmpl_dst; if ( ndst <= 0 ) { if ( col->replace & REPLACE_NON_MISSING ) return 0; // overwrite only if present if ( col->number==BCF_VL_G ) ndst1 = line->n_allele*(line->n_allele+1)/2; else ndst1 = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; hts_expand(float, ndst1*nsmpl_dst, args->mtmpf2, args->tmpf2); for (i=0; itmpf2 + i*ndst1; for (j=0; jnumber==BCF_VL_G ) { map_dip = vcmp_map_dipGvalues(args->vcmp, &nmap_dip); if ( !args->src_smpl_pld ) { args->src_smpl_pld = (uint8_t*) malloc(nsmpl_src); args->dst_smpl_pld = (uint8_t*) malloc(nsmpl_dst); } int pld_src = determine_ploidy(rec->n_allele, args->tmpi, nsrc1, args->src_smpl_pld, nsmpl_src); if ( pld_src<0 ) error("Unexpected number of %s values (%d) for %d alleles at %s:%"PRId64"\n", col->hdr_key_src,-pld_src, rec->n_allele, bcf_seqname(bcf_sr_get_header(args->files,1),rec),(int64_t) rec->pos+1); int pld_dst = determine_ploidy(line->n_allele, args->tmpi2, ndst1, args->dst_smpl_pld, nsmpl_dst); if ( pld_dst<0 ) error("Unexpected number of %s values (%d) for %d alleles at %s:%"PRId64"\n", col->hdr_key_src,-pld_dst, line->n_allele, bcf_seqname(args->hdr,line),(int64_t) line->pos+1); int ndst1_new = pld_dst==1 ? line->n_allele : line->n_allele*(line->n_allele+1)/2; if ( ndst1_new != ndst1 ) { if ( ndst1 ) error("todo: %s ndst1!=ndst .. %d %d at %s:%"PRId64"\n",col->hdr_key_src,ndst1_new,ndst1,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); ndst1 = ndst1_new; hts_expand(float, ndst1*nsmpl_dst, args->mtmpf2, args->tmpf2); } } else if ( !ndst1 ) { ndst1 = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; hts_expand(float, ndst1*nsmpl_dst, args->mtmpf2, args->tmpf2); } for (i=0; isample_map ? args->sample_map[i] : i; float *ptr_src = args->tmpf + i*nsrc1; float *ptr_dst = args->tmpf2 + ii*ndst1; if ( col->number==BCF_VL_G ) { if ( args->src_smpl_pld[ii] > 0 && args->dst_smpl_pld[i] > 0 && args->src_smpl_pld[ii]!=args->dst_smpl_pld[i] ) error("Sample ploidy differs at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); if ( !args->dst_smpl_pld[i] ) for (j=0; jnumber!=BCF_VL_G || args->src_smpl_pld[i]==1 ) { for (j=0; j=0 ) { if ( bcf_float_is_missing(ptr_src[j]) ) bcf_float_set_missing(ptr_dst[k]); else if ( bcf_float_is_vector_end(ptr_src[j]) ) bcf_float_set_vector_end(ptr_dst[k]); else ptr_dst[k] = ptr_src[j]; } } if ( col->number==BCF_VL_G ) for (j=line->n_allele; j=0 ) { if ( bcf_float_is_missing(ptr_src[j]) ) bcf_float_set_missing(ptr_dst[k]); else if ( bcf_float_is_vector_end(ptr_src[j]) ) bcf_float_set_vector_end(ptr_dst[k]); else ptr_dst[k] = ptr_src[j]; } } } } return bcf_update_format_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf2,nsmpl_dst*ndst1); } static int vcf_setter_format_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) { bcf1_t *rec = (bcf1_t*) data; args->tmpp[0] = args->tmps; int ret = bcf_get_format_string(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpp,&args->mtmps); args->tmps = args->tmpp[0]; // tmps might be realloced if ( ret==-3 ) return 0; // the tag is not present if ( ret<=0 ) return 1; // error if ( strcmp("GT",col->hdr_key_dst) ) return core_setter_format_str(args,line,col,args->tmpp); // Genotypes are internally represented as integers. This is a complication for FMT/GT:=oldGT // First determine the maximum number of alleles per-sample ndst1 int nsmpl_src = bcf_hdr_nsamples(args->files->readers[1].header); int nsmpl_dst = bcf_hdr_nsamples(args->hdr_out); int isrc,idst, ndst1 = 0, nsrc1 = ret / nsmpl_src; char *ptr = args->tmps, *ptr_end = ptr + ret; while ( ptr < ptr_end ) { char *smpl_end = ptr + nsrc1; int n = 1; while ( ptr < smpl_end ) { if ( *ptr=='/' || *ptr=='|' ) n++; ptr++; } if ( ndst1 < n ) ndst1 = n; } assert( ndst1 ); int ndst = ndst1*nsmpl_dst; hts_expand(int32_t,ndst,args->mtmpi,args->tmpi); hts_expand(char,ret+1,args->mtmps,args->tmps); args->tmps[ret] = 0; // the FORMAT string may not be 0-terminated for (idst=0; idsttmpi + idst*ndst1; isrc = args->sample_map ? args->sample_map[idst] : idst; if ( isrc==-1 ) { dst[0] = bcf_gt_missing; for (i=1; itmps + isrc*nsrc1, *tmp; char *keep_ptr = beg+nsrc1, keep = *keep_ptr; *keep_ptr = 0; while ( *beg ) { char *end = beg; while ( *end && *end!='/' && *end!='|' ) end++; if ( *beg=='.' && end-beg==1 ) dst[i] = bcf_gt_missing; else { if ( *end=='|' ) is_phased = 1; dst[i] = strtol(beg, &tmp, 10); if ( tmp!=end ) error("Could not parse the %s field at %s:%"PRId64" in %s\n", col->hdr_key_src,bcf_seqname(args->files->readers[1].header,rec),(int64_t) rec->pos+1,args->targets_fname); if ( dst[i] >= line->n_allele ) error("The source allele index is bigger than the number of destination alleles at %s:%"PRId64"\n", bcf_seqname(args->files->readers[1].header,rec),(int64_t) rec->pos+1); dst[i] = is_phased ? bcf_gt_phased(dst[i]) : bcf_gt_unphased(dst[i]); } beg = *end ? end+1 : end; i++; } *keep_ptr = keep; for (; ihdr_out,line,args->tmpi,ndst); } static int init_sample_map(args_t *args, bcf_hdr_t *src, bcf_hdr_t *dst) { int i; if ( !args->sample_names ) { args->nsmpl_annot = bcf_hdr_nsamples(dst); // tab annotation file, expecting that all samples are present: sample map not needed if ( !src ) return 0; int nmatch = 0; for (i=0; isamples[i]); if ( id!=-1 ) nmatch++; } if ( !nmatch ) return -1; // No matching samples found in the source and the destination file args->nsample_map = bcf_hdr_nsamples(dst); args->sample_map = (int*) malloc(sizeof(int)*args->nsample_map); for (i=0; insample_map; i++) { int id = bcf_hdr_id2int(src, BCF_DT_SAMPLE, dst->samples[i]); args->sample_map[i] = id; // idst -> isrc, -1 if not present } return 1; } args->nsample_map = bcf_hdr_nsamples(dst); args->sample_map = (int*) malloc(sizeof(int)*args->nsample_map); for (i=0; insample_map; i++) args->sample_map[i] = -1; int flags = !src ? SMPL_STRICT|SMPL_SINGLE|SMPL_REORDER : SMPL_STRICT|SMPL_SINGLE|SMPL_PAIR2; // is tab vs vcf annotation file smpl_ilist_t *ilist = smpl_ilist_init(dst, args->sample_names, args->sample_is_file, flags); // gives mapping dst->src if ( !ilist || !ilist->n ) error("Could not parse the samples: %s\n", args->sample_names); args->nsmpl_annot = ilist->n; int need_sample_map = args->nsmpl_annot==bcf_hdr_nsamples(dst) ? 0 : 1; for (i=0; insmpl_annot; i++) { int idst = ilist->idx[i]; const char *src_name = ilist->pair && ilist->pair[i] ? ilist->pair[i] : bcf_hdr_int2id(dst, BCF_DT_SAMPLE, idst); int isrc = i; if ( src ) // the annotation file is a VCF, not a tab-delimited file { isrc = bcf_hdr_id2int(src, BCF_DT_SAMPLE, src_name); if ( isrc==-1 ) error("Sample \"%s\" not found in the annotation file\n", src_name); } if ( isrc!=idst ) need_sample_map = 1; args->sample_map[idst] = isrc; } smpl_ilist_destroy(ilist); return need_sample_map; } static char *columns_complement(char *columns, void **skip_info, void **skip_fmt) { kstring_t str = {0,0,0}; char *ss = columns, *se = ss; while ( *ss ) { if ( *se && *se!=',' ) { se++; continue; } if ( *ss!='^' ) { if ( str.l ) kputc(',',&str); kputsn(ss, se-ss, &str); if ( !*se ) break; ss = ++se; continue; } if ( !strncasecmp("^INFO/",ss,6) ) { if ( !*skip_info ) { *skip_info = khash_str2int_init(); if ( str.l ) kputc(',',&str); kputs("INFO",&str); } char tmp = *se; *se = 0; khash_str2int_inc(*skip_info, strdup(ss+6)); *se = tmp; } else if ( !strncasecmp("^FORMAT/",ss,8) || !strncasecmp("^FMT/",ss,5) ) { int n = !strncasecmp("^FMT/",ss,5) ? 5 : 8; if ( !*skip_fmt ) { *skip_fmt = khash_str2int_init(); if ( str.l ) kputc(',',&str); kputs("FORMAT",&str); } char tmp = *se; *se = 0; khash_str2int_inc(*skip_fmt, strdup(ss+n)); *se = tmp; } else { if ( !*skip_info ) { *skip_info = khash_str2int_init(); if ( str.l ) kputc(',',&str); kputs("INFO",&str); } char tmp = *se; *se = 0; khash_str2int_inc(*skip_info, strdup(ss+1)); *se = tmp; } if ( !*se ) break; ss = ++se; } free(columns); return str.s; } static void bcf_hrec_format_rename(bcf_hrec_t *hrec, char *tag, kstring_t *str) { int j, nout = 0; ksprintf(str, "##%s=<", hrec->key); for (j=0; jnkeys; j++) { if ( !strcmp("IDX",hrec->keys[j]) ) continue; if ( nout ) kputc(',',str); if ( !strcmp("ID", hrec->keys[j]) ) ksprintf(str,"%s=%s", hrec->keys[j], tag); else ksprintf(str,"%s=%s", hrec->keys[j], hrec->vals[j]); nout++; } ksprintf(str,">\n"); } static char *set_replace_mode(char *ss, int *replace) { int mode = 0; while (*ss) { if ( *ss=='+' ) mode |= REPLACE_MISSING; else if ( *ss=='-' ) mode |= REPLACE_NON_MISSING; else if ( *ss=='=' ) mode |= SET_OR_APPEND; else if ( *ss=='.' ) mode |= CARRY_OVER_MISSING; else break; ss++; } if ( !mode ) mode = REPLACE_ALL; // is exactly one bit set? // if ( mode && !(mode && ((mode & mode-1) == 0)) ) *replace = mode; return ss; } static void rename_annots_push(args_t *args, char *src, char *dst); static void init_columns(args_t *args) { int need_sample_map = 0; int sample_map_ok = init_sample_map(args, args->tgts_is_vcf?args->files->readers[1].header:NULL, args->hdr); kstring_t tmp = {0,0,0}; if ( args->columns_is_file ) { int i,n; char **str = hts_readlist(args->columns, args->columns_is_file, &n); if ( !str ) error("Could not parse %s\n", args->columns); for (i=0; imerge_method_str.l ) kputc(',',&args->merge_method_str); kputs(str[i],&args->merge_method_str); kputc(':',&args->merge_method_str); kputs(ptr,&args->merge_method_str); } } if ( tmp.l ) kputc(',',&tmp); kputs(str[i],&tmp); free(str[i]); } free(str); free(args->columns); args->columns = tmp.s; tmp.l = tmp.m = 0; tmp.s = NULL; } void *skip_fmt = NULL, *skip_info = NULL; if ( args->tgts_is_vcf ) args->columns = columns_complement(args->columns, &skip_info, &skip_fmt); kstring_t str = {0,0,0}; char *ss = args->columns, *se = ss; args->ncols = 0; int icol = -1, has_fmt_str = 0; while ( *ss ) { char *ptr; if ( *se && *se!=',' ) { se++; continue; } int replace; ss = set_replace_mode(ss, &replace); icol++; str.l = 0; kputsn(ss, se-ss, &str); if ( !str.s[0] || !strcasecmp("-",str.s) ) ; else if ( !strcasecmp("CHROM",str.s) ) args->chr_idx = icol; else if ( !strcasecmp("POS",str.s) ) { if ( replace==REPLACE_NON_MISSING && !args->tgts_is_vcf ) { args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = setter_pos; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); args->match_end = icol; } else args->beg_idx = icol; } else if ( !strcasecmp("FROM",str.s) || !strcasecmp("BEG",str.s) ) args->beg_idx = icol; else if ( !strcasecmp("TO",str.s) || !strcasecmp("END",str.s) ) args->end_idx = icol; else if ( !strcasecmp("REF",str.s) ) { if ( args->tgts_is_vcf ) { args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->setter = vcf_setter_ref; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); } else args->ref_idx = icol; } else if ( !strcasecmp("ALT",str.s) ) { if ( args->tgts_is_vcf ) { args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->setter = vcf_setter_alt; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); col->replace = replace; if ( args->pair_logic==-1 ) bcf_sr_set_opt(args->files,BCF_SR_PAIR_LOGIC,BCF_SR_PAIR_BOTH_REF); } else args->alt_idx = icol; } else if ( !strcasecmp("ID",str.s) || !strcasecmp("~ID",str.s) ) { if ( replace & REPLACE_NON_MISSING ) error("Apologies, the -ID feature has not been implemented yet.\n"); if ( str.s[0]=='~' ) replace = MATCH_VALUE; if ( args->tgts_is_vcf && (replace & MATCH_VALUE) ) error("todo: -c ~ID with -a VCF?\n"); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = args->tgts_is_vcf ? vcf_setter_id : setter_id; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); if ( replace & MATCH_VALUE ) args->match_id = icol; } else if ( !strcasecmp("~INFO/END",str.s) && !args->tgts_is_vcf ) { replace = MATCH_VALUE; args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = NULL; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); args->match_end = icol; } else if ( !strcasecmp("~POS",str.s) ) { error("Error: the use of ~POS has been deprecated, use -POS to transfer the column POS.\n"); } else if ( str.s[0]=='~' ) { args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = MATCH_VALUE; col->setter = NULL; col->hdr_key_src = strdup(str.s+1); } else if ( !strcasecmp("-POS",str.s) && !args->tgts_is_vcf ) { if ( args->tgts_is_vcf ) error("Error: cannot use -POS, position can be replaced only from a tab-delimited file\n"); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = setter_pos; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); args->match_end = icol; } else if ( !strncasecmp("ID:=",str.s,4) ) // transfer a tag from INFO to ID column { if ( !args->tgts_is_vcf ) error("The annotation source must be a VCF for \"%s\"\n",str.s); if ( replace & REPLACE_NON_MISSING ) error("Apologies, the -ID feature has not been implemented yet.\n"); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = vcf_setter_id; col->getter = vcf_getter_info_str2str; str.s[2] = 0; col->hdr_key_dst = strdup(str.s); col->hdr_key_src = strncasecmp("INFO/",str.s+4,5) ? strdup(str.s+4) : strdup(str.s+4+5); int hdr_id = bcf_hdr_id2int(args->tgts_hdr, BCF_DT_ID,col->hdr_key_src); if ( !bcf_hdr_idinfo_exists(args->tgts_hdr,BCF_HL_INFO,hdr_id) ) error("The INFO tag \"%s\" is not defined in %s\n", col->hdr_key_src, args->targets_fname); if ( bcf_hdr_id2type(args->tgts_hdr,BCF_HL_INFO,hdr_id)!=BCF_HT_STR ) error("Only Type=String tags can be used to annotate the ID column\n"); } else if ( (ptr=strstr(str.s,":=")) && (!args->targets_fname || !strncasecmp(ptr+2,"./",2)) ) { *ptr = 0; if ( !strncasecmp(str.s,"INFO/",5) && (!strcasecmp(ptr+2,"FILTER") || !strcasecmp(ptr+2,"./FILTER")) ) { // -a not present and transferring filter, needs to be a local transfer args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = vcf_setter_info_str; col->getter = vcf_getter_filter2str_local; col->hdr_key_src = strdup(ptr+2); col->hdr_key_dst = strdup(str.s+5); tmp.l = 0; ksprintf(&tmp,"##INFO=",col->hdr_key_dst); bcf_hdr_append(args->hdr_out, tmp.s); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, col->hdr_key_dst); col->number = bcf_hdr_id2length(args->hdr_out,BCF_HL_INFO,hdr_id); } else rename_annots_push(args,ptr+2,str.s); *ptr = ':'; } else if ( !strcasecmp("FILTER",str.s) ) { if ( replace & REPLACE_NON_MISSING ) error("Apologies, the -FILTER feature has not been implemented yet.\n"); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = args->tgts_is_vcf ? vcf_setter_filter : setter_filter; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); if ( args->tgts_is_vcf ) { bcf_hdr_t *tgts_hdr = args->files->readers[1].header; int j; for (j=0; jnhrec; j++) { bcf_hrec_t *hrec = tgts_hdr->hrec[j]; if ( hrec->type!=BCF_HL_FLT ) continue; int k = bcf_hrec_find_key(hrec,"ID"); if ( k<0 ) error("[%s] Failed to parse the header, the ID attribute not found", __func__); tmp.l = 0; bcf_hrec_format(hrec, &tmp); bcf_hdr_append(args->hdr_out, tmp.s); } if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); } } else if ( !strcasecmp("QUAL",str.s) ) { if ( replace & REPLACE_NON_MISSING ) error("Apologies, the -QUAL feature has not been implemented yet.\n"); if ( replace & SET_OR_APPEND ) error("Apologies, the =QUAL feature has not been implemented yet.\n"); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; col->setter = args->tgts_is_vcf ? vcf_setter_qual : setter_qual; col->hdr_key_src = strdup(str.s); col->hdr_key_dst = strdup(str.s); } else if ( args->tgts_is_vcf && !strcasecmp("INFO",str.s) ) // All INFO fields { if ( replace & REPLACE_NON_MISSING ) error("Apologies, the -INFO/TAG feature has not been implemented yet.\n"); if ( replace & SET_OR_APPEND ) error("Apologies, the =INFO feature has not been implemented yet.\n"); bcf_hdr_t *tgts_hdr = args->files->readers[1].header; int j; for (j=0; jnhrec; j++) { bcf_hrec_t *hrec = tgts_hdr->hrec[j]; if ( hrec->type!=BCF_HL_INFO ) continue; int k = bcf_hrec_find_key(hrec,"ID"); assert( k>=0 ); // this should always be true for valid VCFs if ( skip_info && khash_str2int_has_key(skip_info,hrec->vals[k]) ) continue; tmp.l = 0; bcf_hrec_format(hrec, &tmp); bcf_hdr_append(args->hdr_out, tmp.s); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, hrec->vals[k]); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = -1; col->replace = replace; col->hdr_key_src = strdup(hrec->vals[k]); col->hdr_key_dst = strdup(hrec->vals[k]); col->number = bcf_hdr_id2length(args->hdr_out,BCF_HL_INFO,hdr_id); switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id) ) { case BCF_HT_FLAG: col->setter = vcf_setter_info_flag; break; case BCF_HT_INT: col->setter = vcf_setter_info_int; break; case BCF_HT_REAL: col->setter = vcf_setter_info_real; break; case BCF_HT_STR: col->setter = vcf_setter_info_str; break; default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id)); } } } else if ( args->tgts_is_vcf && (!strcasecmp("FORMAT",str.s) || !strcasecmp("FMT",str.s)) ) // All FORMAT fields { bcf_hdr_t *tgts_hdr = args->files->readers[1].header; need_sample_map = 1; int j; for (j=0; jnhrec; j++) { bcf_hrec_t *hrec = tgts_hdr->hrec[j]; if ( hrec->type!=BCF_HL_FMT) continue; int k = bcf_hrec_find_key(hrec,"ID"); assert( k>=0 ); // this should always be true for valid VCFs if ( skip_fmt && khash_str2int_has_key(skip_fmt,hrec->vals[k]) ) continue; tmp.l = 0; bcf_hrec_format(hrec, &tmp); bcf_hdr_append(args->hdr_out, tmp.s); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, hrec->vals[k]); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = -1; col->replace = replace; col->hdr_key_src = strdup(hrec->vals[k]); col->hdr_key_dst = strdup(hrec->vals[k]); if ( !strcasecmp("GT",col->hdr_key_src) ) { if ( !args->tgts_is_vcf ) error("The FORMAT/GT field can be currently populated only from a VCF\n"); col->setter = vcf_setter_format_gt; } else switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id) ) { case BCF_HT_INT: col->setter = vcf_setter_format_int; break; case BCF_HT_REAL: col->setter = vcf_setter_format_real; break; case BCF_HT_STR: col->setter = vcf_setter_format_str; has_fmt_str = 1; break; default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id)); } hdr_id = bcf_hdr_id2int(tgts_hdr, BCF_DT_ID, hrec->vals[k]); col->number = bcf_hdr_id2length(tgts_hdr,BCF_HL_FMT,hdr_id); } } else if ( !strncasecmp("FORMAT/",str.s, 7) || !strncasecmp("FMT/",str.s,4) ) { char *key_dst = str.s + (!strncasecmp("FMT/",str.s,4) ? 4 : 7); char *key_src = strstr(key_dst,":="); if ( key_src ) { *key_src = 0; key_src += 2; if ( !strncasecmp("FORMAT/",key_src,7) ) key_src += 7; else if ( !strncasecmp("FMT/",key_src,4) ) key_src += 4; } else key_src = key_dst; need_sample_map = 1; if ( args->tgts_is_vcf ) { bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->files->readers[1].header, BCF_HL_FMT, "ID", key_src, NULL); if ( !hrec ) error("No such annotation \"%s\" in %s\n", key_src,args->targets_fname); tmp.l = 0; bcf_hrec_format_rename(hrec, key_dst, &tmp); bcf_hdr_append(args->hdr_out, tmp.s); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); } int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, key_dst); if ( !bcf_hdr_idinfo_exists(args->hdr_out,BCF_HL_FMT,hdr_id) ) error("The FORMAT tag \"%s\" is not defined in %s, was the -h option provided?\n", str.s, args->targets_fname); args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); if ( !args->tgts_is_vcf ) { col->icol = icol; icol += args->nsmpl_annot - 1; } else col->icol = -1; col->replace = replace; col->hdr_key_src = strdup(key_src); col->hdr_key_dst = strdup(key_dst); if ( !strcasecmp("GT",key_src) ) { if ( !args->tgts_is_vcf ) error("The FORMAT/GT field can be currently populated only from a VCF\n"); col->setter = vcf_setter_format_gt; } else switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id) ) { case BCF_HT_INT: col->setter = args->tgts_is_vcf ? vcf_setter_format_int : setter_format_int; break; case BCF_HT_REAL: col->setter = args->tgts_is_vcf ? vcf_setter_format_real : setter_format_real; break; case BCF_HT_STR: col->setter = args->tgts_is_vcf ? vcf_setter_format_str : setter_format_str; has_fmt_str = 1; break; default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id)); } if ( args->tgts_is_vcf ) { bcf_hdr_t *tgts_hdr = args->files->readers[1].header; hdr_id = bcf_hdr_id2int(tgts_hdr, BCF_DT_ID, col->hdr_key_src); col->number = bcf_hdr_id2length(tgts_hdr,BCF_HL_FMT,hdr_id); } } else { if ( replace & REPLACE_NON_MISSING ) error("Apologies, the -INFO/TAG feature has not been implemented yet.\n"); if ( replace & SET_OR_APPEND ) { if ( args->tgts_is_vcf ) error("Error: the =INFO/TAG feature is currently supported only with TAB annotation files and has limitations\n" " (the annotation type is modified to \"Number=.\" and allele ordering is disregarded)\n"); fprintf(stderr,"Warning: the =INFO/TAG feature modifies the annotation to \"Number=.\" and disregards allele ordering\n"); } args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); annot_col_t *col = &args->cols[args->ncols-1]; memset(col,0,sizeof(*col)); col->icol = icol; col->replace = replace; int explicit_src_info = 0; int explicit_dst_info = 0; char *key_dst; if ( !strncasecmp("INFO/",str.s,5) ) { key_dst = str.s + 5; explicit_dst_info = 1; } else if ( !strcasecmp("~INFO/END",str.s) ) { key_dst = str.s + 6; explicit_dst_info = 1; } else key_dst = str.s; char *key_src = strstr(key_dst,":="); if ( key_src ) { *key_src = 0; key_src += 2; if ( !strncasecmp("INFO/",key_src,5) ) { key_src += 5; explicit_src_info = 1; } else if ( !strncasecmp("FMT/",key_src,4) || !strncasecmp("FORMAT/",key_src,5) ) { key_src[-2] = ':'; error("Did you mean \"FMT/%s\" rather than \"%s\"?\n",str.s,str.s); } else if ( !strcasecmp("FILTER",key_src) && args->tgts_is_vcf ) { col->getter = vcf_getter_filter2str; } } else key_src = key_dst; col->hdr_key_src = strdup(key_src); col->hdr_key_dst = strdup(key_dst); int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, key_dst); if ( !bcf_hdr_idinfo_exists(args->hdr_out,BCF_HL_INFO,hdr_id) ) { if ( args->tgts_is_vcf ) // reading annotations from a VCF, add a new header line { if ( !strcasecmp("ID",key_src) && !explicit_src_info ) { // transferring ID column into a new INFO tag tmp.l = 0; ksprintf(&tmp,"##INFO=",key_dst); } else if ( !strcasecmp("FILTER",key_src) && !explicit_src_info ) { // transferring FILTER column into a new INFO tag tmp.l = 0; ksprintf(&tmp,"##INFO=",key_dst); } else { bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->files->readers[1].header, BCF_HL_INFO, "ID", key_src, NULL); if ( !hrec ) { if ( explicit_dst_info+explicit_src_info==0 && bcf_hdr_get_hrec(args->files->readers[1].header, BCF_HL_FMT, "ID", key_src, NULL) ) error("Did you mean \"FMT/%s\" rather than \"%s\"?\n",str.s,str.s); char *ptr = strchr(key_src,'='); if ( ptr ) { *ptr = 0; tmp.l = 0; ksprintf(&tmp,"%s:=%s",key_src,ptr+1); *ptr = '='; error("The INFO tag \"%s\" is not defined, is this what you want \"%s\" ?\n",key_src,tmp.s); } error("The INFO tag \"%s\" is not defined in %s, was the -h option provided?\n", key_src,args->files->readers[1].fname); } tmp.l = 0; bcf_hrec_format_rename(hrec, key_dst, &tmp); } bcf_hdr_append(args->hdr_out, tmp.s); if (bcf_hdr_sync(args->hdr_out) < 0) error_errno("[%s] Failed to update header", __func__); hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, key_dst); } else error("The INFO tag \"%s\" is not defined in %s, was the -h option provided?\n", key_dst, args->targets_fname); assert( bcf_hdr_idinfo_exists(args->hdr_out,BCF_HL_INFO,hdr_id) ); } if ( args->tgts_is_vcf ) { if ( !strcasecmp("ID",key_src) && !explicit_src_info ) col->getter = vcf_getter_id2str; else if ( !strcasecmp("FILTER",key_src) && !explicit_src_info ) col->getter = vcf_getter_filter2str; } col->number = bcf_hdr_id2length(args->hdr_out,BCF_HL_INFO,hdr_id); switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id) ) { case BCF_HT_FLAG: col->setter = args->tgts_is_vcf ? vcf_setter_info_flag : setter_info_flag; break; case BCF_HT_INT: col->setter = args->tgts_is_vcf ? vcf_setter_info_int : setter_info_int; break; case BCF_HT_REAL: col->setter = args->tgts_is_vcf ? vcf_setter_info_real : setter_info_real; break; case BCF_HT_STR: col->setter = args->tgts_is_vcf ? vcf_setter_info_str : setter_info_str; break; default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id)); } if ( replace & SET_OR_APPEND ) // change to Number=. { bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->hdr_out, BCF_HL_INFO, "ID", key_dst, NULL); if ( !hrec ) error("Uh, could not find the new tag \"%s\" in the header\n", key_dst); hrec = bcf_hrec_dup(hrec); int j = bcf_hrec_find_key(hrec, "Number"); if ( j<0 ) error("Uh, could not find the entry Number in the header record of %s\n",key_dst); free(hrec->vals[j]); hrec->vals[j] = strdup("."); bcf_hdr_remove(args->hdr_out,BCF_HL_INFO, key_dst); bcf_hdr_add_hrec(args->hdr_out, hrec); } } if ( !*se ) break; ss = ++se; } free(str.s); free(tmp.s); free(args->columns); if ( skip_info ) khash_str2int_destroy_free(skip_info); if ( skip_fmt ) khash_str2int_destroy_free(skip_fmt); if ( has_fmt_str ) { int n = bcf_hdr_nsamples(args->hdr_out); if ( args->tgts_is_vcf && nfiles->readers[1].header) ) n = bcf_hdr_nsamples(args->files->readers[1].header); args->tmpp = (char**)malloc(sizeof(char*)*n); args->tmpp2 = (char**)malloc(sizeof(char*)*n); } if ( !need_sample_map ) { free(args->sample_map); args->sample_map = NULL; } else if ( sample_map_ok<0 ) error("No matching samples in source and destination file?\n"); } static void init_merge_method(args_t *args) { int i; for (i=0; incols; i++) { args->cols[i].merge_method = MM_FIRST; args->cols[i].mm_str_hash = NULL; args->cols[i].mm_dbl = NULL; args->cols[i].mm_dbl_nalloc = args->cols[i].mm_dbl_nused = args->cols[i].mm_dbl_ndat = 0; memset(&args->cols[i].mm_kstr, 0, sizeof(args->cols[i].mm_kstr)); } if ( !args->merge_method_str.l ) return; if ( args->tgts_is_vcf ) error("Error: the --merge-logic is intended for use with BED or TAB-delimited files only.\n"); if ( !args->tgt_idx && !args->tgts ) error("Error: BEG,END (or FROM,TO) columns or REF,ALT columns are expected with the --merge-logic option.\n"); char *sb = args->merge_method_str.s; while ( *sb ) { char *se = sb; while ( *se && *se!=',' ) se++; args->tmpks.l = 0; kputsn(sb, se-sb, &args->tmpks); kputc(0, &args->tmpks); char *mm_type_str = args->tmpks.s + args->tmpks.l; while ( *mm_type_str!=':' && mm_type_str > args->tmpks.s ) mm_type_str--; if ( *mm_type_str!=':' ) error("Error: could not parse the argument to --merge-logic: %s\n", args->merge_method_str.s); *mm_type_str = 0; mm_type_str++; int mm_type = MM_FIRST; if ( !strcasecmp("unique",mm_type_str) ) mm_type = MM_UNIQUE; else if ( !strcasecmp("first",mm_type_str) ) mm_type = MM_FIRST; else if ( !strcasecmp("append",mm_type_str) ) mm_type = MM_APPEND; else if ( !strcasecmp("append-missing",mm_type_str) ) { mm_type = MM_APPEND_MISSING; if ( args->ref_idx!=-1 ) args->has_append_mode = 1; } else if ( !strcasecmp("sum",mm_type_str) ) mm_type = MM_SUM; else if ( !strcasecmp("avg",mm_type_str) ) mm_type = MM_AVG; else if ( !strcasecmp("min",mm_type_str) ) mm_type = MM_MIN; else if ( !strcasecmp("max",mm_type_str) ) mm_type = MM_MAX; else error("Error: could not parse --merge-logic %s, the logic \"%s\" is not recognised\n", args->merge_method_str.s,mm_type_str); for (i=0; incols; i++) { if ( strcmp(args->cols[i].hdr_key_dst,args->tmpks.s) ) continue; if ( (mm_type==MM_APPEND || mm_type==MM_APPEND_MISSING) && args->cols[i].number!=BCF_VL_VAR ) error("Error: --merge-logic append can be requested only for tags of variable length (Number=.)\n"); args->cols[i].merge_method = mm_type; break; } if ( i==args->ncols ) error("No such tag in the destination file: %s\n", args->tmpks.s); sb = *se ? se + 1 : se; } if ( args->has_append_mode ) { // create a missing line to insert missing values when VCF ALT finds no match in the annotation file args->aline_missing = (annot_line_t*)calloc(1,sizeof(*args->aline_missing)); int ncol = 0; for (i=0; incols; i++) if ( ncol < args->cols[i].icol + 1 ) ncol = args->cols[i].icol + 1; if ( ncol < args->ref_idx + 1 ) ncol = args->ref_idx + 1; args->aline_missing->mcols = ncol; args->aline_missing->ncols = ncol; args->aline_missing->cols = (char**) malloc(ncol*sizeof(char*)); for (i=0; ialine_missing->cols[i] = strdup("."); } } static void rename_chrs(args_t *args, char *fname) { int n, i; char **map = hts_readlist(fname, 1, &n); if ( !map ) error("Could not read: %s\n", fname); for (i=0; ihdr_out, map[i]); bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->hdr_out, BCF_HL_CTG, "ID", map[i], NULL); if ( !hrec ) continue; // the sequence not present int j = bcf_hrec_find_key(hrec, "ID"); assert( j>=0 ); free(hrec->vals[j]); ss++; while ( *ss && isspace(*ss) ) ss++; char *se = ss; while ( *se && !isspace(*se) ) se++; *se = 0; hrec->vals[j] = strdup(ss); args->hdr_out->id[BCF_DT_CTG][rid].key = hrec->vals[j]; } for (i=0; ihdr_out, BCF_DT_ID, ori_tag); if ( id<0 ) return 1; bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->hdr_out, type, "ID", ori_tag, NULL); if ( !hrec ) return 1; // the ID attribute not present int j = bcf_hrec_find_key(hrec, "ID"); assert( j>=0 ); free(hrec->vals[j]); char *ptr = new_tag; while ( *ptr && !isspace(*ptr) ) ptr++; *ptr = 0; hrec->vals[j] = strdup(new_tag); args->hdr_out->id[BCF_DT_ID][id].key = hrec->vals[j]; return 0; } static void rename_annots(args_t *args) { int i; if ( args->rename_annots ) { args->rename_annots_map = hts_readlist(args->rename_annots, 1, &args->rename_annots_nmap); if ( !args->rename_annots_map ) error("Could not read: %s\n", args->rename_annots); } for (i=0; irename_annots_nmap; i++) { char *ptr = args->rename_annots_map[i]; while ( *ptr && !isspace(*ptr) ) ptr++; if ( !*ptr ) error("Could not parse: %s\n", args->rename_annots_map[i]); char *rmme = ptr; *ptr = 0; ptr++; while ( *ptr && isspace(*ptr) ) ptr++; if ( !*ptr ) { *rmme = ' '; error("Could not parse: %s\n", args->rename_annots_map[i]); } if ( rename_annots_core(args, args->rename_annots_map[i], ptr) < 0 ) error("Cannot rename \"%s\" to \"%s\"\n",args->rename_annots_map[i],ptr); } } static void rename_annots_push(args_t *args, char *src, char *dst) { args->rename_annots_nmap++; args->rename_annots_map = (char**)realloc(args->rename_annots_map,sizeof(*args->rename_annots_map)*args->rename_annots_nmap); kstring_t str = {0,0,0}; ksprintf(&str,"%s %s",src,dst); args->rename_annots_map[ args->rename_annots_nmap - 1 ] = str.s; } static void init_filters(args_t *args) { // Check if the -i/-e expressions contain external values that should be determined // on the fly from the annotation file. The expressions can be given as // TAG={NAME} // TAG={str:NAME} // TAG={int:NAME} // TAG={float:NAME} kstring_t str = {0,0,0}; char *src = strdup(args->filter_str); int len = 0; while (1) { char *beg = strchr(src+len,'{'); if ( !beg ) break; // check if "{" appears inside quotes, in such case do not modify char skip = 0; char *tmp = src; while ( tmpfilter_str); // unbalanced quotation; todo: check for escape char len = tmp - src + 1; skip = 1; } if ( skip ) continue; char *end = ++beg; while ( *end && *end!='}' ) end++; if ( !*end ) error("Could not parse the expression: %s\n",args->filter_str); *end = 0; // explicit typing? int type = -1; tmp = beg; while ( *tmp && *tmp!=':' ) tmp++; if ( *tmp ) { *tmp = 0; if ( !strcasecmp(beg,"str") ) type = BCF_HT_STR; else if ( !strcasecmp(beg,"int") ) type = BCF_HT_INT; else if ( !strcasecmp(beg,"float") ) type = BCF_HT_REAL; } args->n_ext++; args->ext = (ext_t*)realloc(args->ext,sizeof(*args->ext)*args->n_ext); ext_t *ext = &args->ext[args->n_ext-1]; ext->ht_type = type; ext->name = strdup(beg); if ( beg-1 > src ) kputsn(src,beg-1-src,&str); if ( type==-1 ) kputs("{}",&str); else if ( type==BCF_HT_STR ) kputs("{str}",&str); else if ( type==BCF_HT_INT ) kputs("{int}",&str); else if ( type==BCF_HT_REAL ) kputs("{float}",&str); len = str.l; kputs(end+1,&str); free(src); src = strdup(str.s); str.l = 0; } args->filter = filter_init(args->hdr, src); free(src); free(str.s); int i,j,n_ext; const int *ext_type = filter_ext_types(args->filter, &n_ext); if ( n_ext != args->n_ext ) error("Failed to parse the expression, unexpected number of dynamic variables (%d vs %d): %s\n",n_ext,args->n_ext,args->filter_str); if ( !args->n_ext ) return; if ( !args->tgts ) error("Error: dynamic variables in -i/-e expressions can be currently used only with tab-delimited file, not with VCF (todo)\n"); // contains external values args->ext_ptr = malloc(sizeof(*args->ext_ptr)*args->n_ext); for (i=0; in_ext; i++) args->ext[i].ht_type = ext_type[i]; args->filter_ext = args->filter; args->filter = NULL; // set the column idx if ( args->ncols ) { for (i=0; in_ext; i++) { for (j=0; jncols; j++) { if ( strcmp(args->ext[i].name,args->cols[j].hdr_key_src) ) continue; args->ext[i].icol = args->cols[j].icol; break; } if ( j==args->ncols ) error("No such column: %s\n",args->ext[i].name); } } } static void init_data(args_t *args) { args->hdr = args->files->readers[0].header; args->hdr_out = bcf_hdr_dup(args->hdr); if ( args->set_ids_fmt ) { if ( args->set_ids_fmt[0]=='+' ) { args->set_ids_replace = 0; args->set_ids_fmt++; } args->set_ids = convert_init(args->hdr_out, NULL, 0, args->set_ids_fmt); } if ( args->remove_annots ) init_remove_annots(args); if ( args->header_fname || args->header_lines ) init_header_lines(args); if ( args->targets_fname && args->tgts_is_vcf ) { // reading annots from a VCF if ( !bcf_sr_add_reader(args->files, args->targets_fname) ) error("Failed to open %s: %s\n", args->targets_fname,bcf_sr_strerror(args->files->errnum)); args->tgts_hdr = args->files->readers[1].header; } if ( args->columns ) init_columns(args); if ( args->targets_fname && !args->tgts_is_vcf ) { if ( !args->columns ) error("The -c option not given\n"); if ( args->chr_idx==-1 ) error("The -c CHROM option not given\n"); if ( args->beg_idx==-1 ) error("The -c POS option not given\n"); if ( args->single_overlaps && args->merge_method_str.l ) error("The options --merge-logic and --single-overlaps cannot be combined\n"); if ( args->end_idx==-1 || (args->single_overlaps && !args->merge_method_str.l) ) { args->end_idx = -args->beg_idx - 1; args->tgts = bcf_sr_regions_init(args->targets_fname,1,args->chr_idx,args->beg_idx,args->end_idx); if ( !args->tgts ) error("Could not initialize the annotation file: %s\n", args->targets_fname); if ( !args->tgts->tbx ) error("Expected tabix-indexed annotation file: %s\n", args->targets_fname); } else { if ( args->ref_idx!=-1 ) error("Error: the REF columns will be ignored when BEG,END (or FROM,TO) is present. Replace END (or TO) with \"-\".\n"); int len = strlen(args->targets_fname); if ( len>=7 && !strcasecmp(".bed.gz",args->targets_fname+len-7) ) args->tgt_is_bed = 1; else if ( len>=8 && !strcasecmp(".bed.bgz",args->targets_fname+len-8) ) args->tgt_is_bed = 1; else if ( len>=4 && !strcasecmp(".bed",args->targets_fname+len-4) ) args->tgt_is_bed = 1; args->tgt_idx = regidx_init(args->targets_fname,parse_with_payload,free_payload,sizeof(char*),args); if ( !args->tgt_idx ) error("Failed to parse: %s\n", args->targets_fname); args->tgt_itr = regitr_init(args->tgt_idx); args->nalines++; hts_expand0(annot_line_t,args->nalines,args->malines,args->alines); } if ( args->min_overlap_str ) { char *tmp = args->min_overlap_str; if ( args->min_overlap_str[0] != ':' ) { args->min_overlap_ann = strtod(args->min_overlap_str,&tmp); if ( args->min_overlap_ann < 0 || args->min_overlap_ann > 1 || (*tmp && *tmp!=':') ) error("Could not parse \"--min-overlap %s\", expected value(s) between 0-1\n", args->min_overlap_str); } if ( *tmp && *tmp==':' ) { args->min_overlap_vcf = strtod(tmp+1,&tmp); if ( args->min_overlap_vcf < 0 || args->min_overlap_vcf > 1 || *tmp ) error("Could not parse \"--min-overlap %s\", expected value(s) between 0-1\n", args->min_overlap_str); } } } init_merge_method(args); args->vcmp = vcmp_init(); if ( args->filter_str ) init_filters(args); if ( args->mark_sites ) { if ( !args->targets_fname ) { if ( args->mark_sites_logic!=MARK_LISTED ) error("The -a option not given but -%s logic was requested\n",args->mark_sites); fprintf(stderr,"Note: The -a option not given, all sites will be annotated with INFO/%s\n",args->mark_sites); bcf_hdr_printf(args->hdr_out,"##INFO=", args->mark_sites,args->mark_sites); } else bcf_hdr_printf(args->hdr_out,"##INFO=", args->mark_sites,args->mark_sites_logic==MARK_LISTED?"":"not ",args->mark_sites); } if (args->record_cmd_line) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_annotate"); if ( !args->drop_header ) { if ( args->rename_chrs ) rename_chrs(args, args->rename_chrs); if ( args->rename_annots || args->rename_annots_map ) rename_annots(args); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("[%s] Error: cannot write to \"%s\": %s\n", __func__,args->output_fname, strerror(errno)); if ( args->n_threads ) hts_set_opt(args->out_fh, HTS_OPT_THREAD_POOL, args->files->p); if ( bcf_hdr_write(args->out_fh, args->hdr_out)!=0 ) error("[%s] Error: failed to write the header to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr,args->output_fname, &args->index_fn, args->write_index) < 0 ) error("Error: failed to initialise index for %s\n",args->output_fname); } } static void destroy_data(args_t *args) { int i; for (i=0; in_ext; i++) { free(args->ext[i].name); if ( args->ext[i].ht_type!=BCF_HT_STR ) continue; } free(args->ext_ptr); free(args->ext); for (i=0; inrm; i++) free(args->rm[i].key); free(args->rm); if ( args->hdr_out ) bcf_hdr_destroy(args->hdr_out); if (args->vcmp) vcmp_destroy(args->vcmp); for (i=0; incols; i++) { free(args->cols[i].hdr_key_src); free(args->cols[i].hdr_key_dst); free(args->cols[i].mm_kstr.s); if ( args->cols[i].mm_str_hash ) khash_str2int_destroy_free(args->cols[i].mm_str_hash); free(args->cols[i].mm_dbl); free(args->cols[i].ptr); } free(args->cols); if ( args->aline_missing ) { for (i=0; ialine_missing->ncols; i++) free(args->aline_missing->cols[i]); free(args->aline_missing->cols); free(args->aline_missing); } for (i=0; imalines; i++) { free(args->alines[i].cols); free(args->alines[i].als); free(args->alines[i].line.s); } free(args->alines); free(args->srt_alines); if ( args->tgt_idx ) { regidx_destroy(args->tgt_idx); regitr_destroy(args->tgt_itr); } if ( args->rename_annots_map ) { for (i=0; irename_annots_nmap; i++) free(args->rename_annots_map[i]); free(args->rename_annots_map); } if ( args->tgts ) bcf_sr_regions_destroy(args->tgts); free(args->tmpks.s); free(args->tmpi); free(args->tmpf); free(args->tmps); free(args->tmpp); free(args->tmpi2); free(args->tmpf2); free(args->tmps2); free(args->tmpp2); free(args->tmpi3); free(args->tmpf3); free(args->src_smpl_pld); free(args->dst_smpl_pld); if ( args->set_ids ) convert_destroy(args->set_ids); if ( args->filter ) filter_destroy(args->filter); if ( args->filter_ext ) filter_destroy(args->filter_ext); if (args->out_fh) { if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); } free(args->sample_map); free(args->merge_method_str.s); } static void parse_annot_line(args_t *args, char *str, annot_line_t *tmp) { tmp->line.l = 0; kputs(str, &tmp->line); char *s = tmp->line.s; tmp->ncols = 1; hts_expand(char*,tmp->ncols,tmp->mcols,tmp->cols); tmp->cols[0] = s; while ( *s ) { if ( *s=='\t' ) { tmp->ncols++; hts_expand(char*,tmp->ncols,tmp->mcols,tmp->cols); tmp->cols[tmp->ncols-1] = s+1; *s = 0; } s++; } if ( args->ref_idx != -1 ) { if ( args->ref_idx >= tmp->ncols ) error("Could not parse the line, expected %d+ columns, found %d:\n\t%s\n",args->ref_idx+1,tmp->ncols,str); if ( args->alt_idx >= tmp->ncols ) error("Could not parse the line, expected %d+ columns, found %d:\n\t%s\n",args->alt_idx+1,tmp->ncols,str); tmp->nals = 2; hts_expand(char*,tmp->nals,tmp->mals,tmp->als); tmp->als[0] = tmp->cols[args->ref_idx]; tmp->als[1] = s = tmp->cols[args->alt_idx]; while ( *s ) { if ( *s==',' ) { tmp->nals++; hts_expand(char*,tmp->nals,tmp->mals,tmp->als); tmp->als[tmp->nals-1] = s+1; *s = 0; } s++; } } } static void buffer_annot_lines(args_t *args, bcf1_t *line, int start_pos, int end_pos) { if ( args->nalines && args->alines[0].rid != line->rid ) args->nalines = 0; int i = 0; while ( inalines ) { if ( line->pos > args->alines[i].end ) { args->nalines--; if ( args->nalines && inalines ) { annot_line_t tmp = args->alines[i]; memmove(&args->alines[i],&args->alines[i+1],(args->nalines-i)*sizeof(annot_line_t)); args->alines[args->nalines] = tmp; } } else i++; } if ( !args->filter_ext && args->ref_idx==-1 && args->nalines ) return; while ( !bcf_sr_regions_overlap(args->tgts, bcf_seqname(args->hdr,line), start_pos,end_pos) ) { if ( args->nalines + 1 == 0xffff ) break; // likely a symbolic allele, don't let the buffer overflow args->nalines++; hts_expand0(annot_line_t,args->nalines,args->malines,args->alines); annot_line_t *tmp = &args->alines[args->nalines-1]; tmp->rid = line->rid; tmp->start = args->tgts->start; tmp->end = args->tgts->end; parse_annot_line(args, args->tgts->line.s, tmp); if ( args->filter_ext || args->ref_idx != -1 ) { int iseq = args->tgts->iseq; if ( bcf_sr_regions_next(args->tgts)<0 || args->tgts->iseq!=iseq ) break; } else break; } } // search string in semicolon separated strings (xx vs aa;bb) static int str_match(char *needle, char *haystack) { int len = strlen(needle); char *ptr = haystack; while ( *ptr && (ptr=strstr(ptr,needle)) ) { if ( ptr[len]!=0 && ptr[len]!=';' ) ptr++; // a prefix, not a match else if ( ptr==haystack || ptr[-1]==';' ) return 1; // a match ptr++; // a suffix, not a match } return 0; } // search common string in semicolon separated strings (xx;yy;zz vs aa;bb) static int strstr_match(char *a, char *b) { char *beg = a; while ( *beg ) { char *end = beg; while ( *end && *end!=';' ) end++; char tmp = *end; if ( *end==';' ) *end = 0; int ret = str_match(beg,b); *end = tmp; if ( ret || !*end ) return ret; beg = end + 1; } return 0; } static int annotate_from_regidx(args_t *args, bcf1_t *line) { int j; int has_overlap = 0; for (j=0; jncols; j++) args->cols[j].done = 0; if ( regidx_overlap(args->tgt_idx, bcf_seqname(args->hdr,line),line->pos,line->pos+line->rlen-1, args->tgt_itr) ) { hts_pos_t vcf_end = line->pos + line->rlen - 1; while ( regitr_overlap(args->tgt_itr) ) { annot_line_t *tmp = &args->alines[0]; tmp->rid = line->rid; tmp->start = args->tgt_itr->beg; tmp->end = args->tgt_itr->end; // Check min overlap int len_ann = tmp->end - tmp->start + 1; int len_vcf = line->rlen; int isec = (tmp->end < vcf_end ? tmp->end : vcf_end) - (tmp->start > line->pos ? tmp->start : line->pos) + 1; assert( isec > 0 ); if ( args->min_overlap_ann && args->min_overlap_ann > (float)isec/len_ann ) continue; if ( args->min_overlap_vcf && args->min_overlap_vcf > (float)isec/len_vcf ) continue; parse_annot_line(args, regitr_payload(args->tgt_itr,char*), tmp); // If a plain BED file is provided and we are asked to just mark overlapping sites, there are // no additional columns. Not sure if there can be any side effects for ill-formatted BED files // with variable number of columns if ( !args->ncols && args->mark_sites ) has_overlap = 1; for (j=0; jncols; j++) { if ( args->cols[j].done==1 ) continue; int ret = args->cols[j].setter(args,line,&args->cols[j],tmp); if ( ret < 0 ) error("fixme: Could not set %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); if ( ret==0 ) args->cols[j].done = 1; has_overlap = 1; } } } for (j=0; jncols; j++) { if ( args->cols[j].done==1 || args->cols[j].merge_method == MM_FIRST ) continue; if ( !args->cols[j].setter ) continue; if ( args->cols[j].setter(args,line,&args->cols[j],NULL) < 0 ) error("fixme: Could not set %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); } return has_overlap; } static int pass_filter_test_ext(args_t *args, bcf1_t *line, annot_line_t *ann) { char *tmp; int i; for (i=0; in_ext; i++) { int j = args->ext[i].icol; if ( args->ext[i].ht_type==BCF_HT_STR ) args->ext_ptr[i] = args->ext[i].s = ann->cols[j]; else if ( args->ext[i].ht_type==BCF_HT_INT ) { args->ext[i].i = strtol(ann->cols[j],&tmp,10); if ( *tmp ) { if ( strcmp(".",ann->cols[j]) ) error("Error: could not parse the annotation file, expected an integer, found \"%s\"\n",ann->cols[j]); args->ext_ptr[i] = NULL; } else args->ext_ptr[i] = &args->ext[i].i; } else if ( args->ext[i].ht_type==BCF_HT_REAL ) { args->ext[i].f = strtod(ann->cols[j],&tmp); if ( *tmp ) { if ( strcmp(".",ann->cols[j]) ) error("Error: could not parse the annotation file, expected a float, found \"%s\"\n",ann->cols[j]); args->ext_ptr[i] = NULL; } else args->ext_ptr[i] = &args->ext[i].f; } } int pass = filter_test_ext(args->filter_ext,line,NULL,(const void**)args->ext_ptr); if ( args->filter_logic==FLT_EXCLUDE ) pass = pass ? 0 : 1; return pass; } static int annotate_from_tab(args_t *args, bcf1_t *line) { int i,j; int has_overlap = 0; // Buffer annotation lines. When multiple ALT alleles are present in the annotation file, at least one // must match some of the VCF alleles. If the append-missing mode is set (and REF+ALT is requested), the // buffered lines will annotate the VCF respecting the order in ALT and when no matching line is found // for an ALT, missing value is appended instead. int end_pos = line->pos + line->rlen - 1; buffer_annot_lines(args, line, line->pos, end_pos); args->nsrt_alines = 0; hts_expand(uint32_t,args->nalines,args->msrt_alines,args->srt_alines); if ( args->nalines >= 0xffff || line->n_allele >= 0xffff ) error("Error: too many alleles or annotation lines in the buffer at %s:%"PRId64" (todo:skip?)\n",bcf_seqname(args->hdr,line),(int64_t) line->pos+1); kstring_t match_end = {0,0,0}; if ( args->match_end>=0 && bcf_get_info_int32(args->hdr,line,"END",&args->tmpi,&args->mtmpi)==1 ) kputw(args->tmpi[0],&match_end); // Find matching lines for (i=0; inalines; i++) { if ( line->pos > args->alines[i].end || end_pos < args->alines[i].start ) continue; if ( args->ref_idx != -1 ) // REF+ALT matching requested { if ( line->pos!=args->alines[i].start || vcmp_set_ref(args->vcmp, line->d.allele[0], args->alines[i].als[0]) < 0 ) continue; // refs are not compatible for (j=1; jalines[i].nals; j++) { int ialt; if ( line->n_allele==1 && args->alines[i].als[j][0]=='.' && args->alines[i].als[j][1]==0 ) // match: no ALT allele in VCF and annot file has "." ialt = 0; else { ialt = vcmp_find_allele(args->vcmp, line->d.allele+1, line->n_allele - 1, args->alines[i].als[j]); if ( ialt < 0 ) continue; ialt++; } if ( args->match_id>=0 && !strstr_match(line->d.id,args->alines[i].cols[args->match_id]) ) continue; if ( args->match_end>=0 && match_end.l && strcmp(match_end.s,args->alines[i].cols[args->match_end]) ) continue; if ( args->filter_ext && !pass_filter_test_ext(args,line,&args->alines[i]) ) continue; args->srt_alines[args->nsrt_alines++] = (ialt<<16) | i; has_overlap = 1; break; } } else if ( args->filter_ext ) { if ( pass_filter_test_ext(args,line,&args->alines[i]) ) { args->srt_alines[args->nsrt_alines++] = (0xffff<<16) | i; has_overlap = 1; } } else // overlap, REF+ALT matching not requested { args->srt_alines[args->nsrt_alines++] = (0xffff<<16) | i; has_overlap = 1; } } free(match_end.s); if ( !has_overlap && args->filter_ext && !args->keep_sites ) return has_overlap; // Sort lines if needed if ( args->has_append_mode ) { // insertion sort by VCF ALT index (top bits) and alines index (low bits) uint32_t tmp; for (i=1; insrt_alines; i++) for (j=i; j>0 && args->srt_alines[j] < args->srt_alines[j-1]; j--) tmp = args->srt_alines[j], args->srt_alines[j] = args->srt_alines[j-1], args->srt_alines[j-1] = tmp; } // Annotate for (j=0; jncols; j++) args->cols[j].done = 0; int ialt_exp = 1; for (i=0; insrt_alines; i++) { int ialt = args->srt_alines[i] >> 16; int ilin = args->srt_alines[i] & 0xffff; if ( args->has_append_mode ) { if ( ialt_exp > ialt ) continue; // multiple annotation lines for the same position if ( ialt_exp < ialt ) { // REF+ALT matching requested, append-missing mode: insert "." if no annotation line was found for the ALT while ( ialt_exp++ < ialt ) { for (j=0; jncols; j++) { if ( args->cols[j].merge_method != MM_APPEND_MISSING ) continue; if ( args->cols[j].done==1 ) continue; if ( !args->cols[j].setter ) continue; int ret = args->cols[j].setter(args,line,&args->cols[j],args->aline_missing); if ( ret < 0 ) error("fixme: Could not set missing %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); if ( ret==0 ) args->cols[j].done = 1; } } } } for (j=0; jncols; j++) { if ( args->cols[j].done==1 ) continue; if ( !args->cols[j].setter ) continue; int ret = args->cols[j].setter(args,line,&args->cols[j],&args->alines[ilin]); if ( ret < 0 ) error("fixme: Could not set %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); if ( ret==0 ) args->cols[j].done = 1; } ialt_exp = ialt + 1; } if ( args->nsrt_alines ) { // In the append-missing mode fill missing values to all trailing ALTs, but only if at least one // record was found. Otherwise leave the row will be left without annotation. if ( args->has_append_mode && ialt_exp < line->n_allele ) { while ( ialt_exp++ < line->n_allele ) { for (j=0; jncols; j++) { if ( args->cols[j].merge_method != MM_APPEND_MISSING ) continue; if ( args->cols[j].done==1 ) continue; if ( !args->cols[j].setter ) continue; int ret = args->cols[j].setter(args,line,&args->cols[j],args->aline_missing); if ( ret < 0 ) error("fixme: Could not set missing %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); if ( ret==0 ) args->cols[j].done = 1; } } } // Flush for (j=0; jncols; j++) { if ( args->cols[j].done==1 || args->cols[j].merge_method == MM_FIRST ) continue; if ( !args->cols[j].setter ) continue; int ret = args->cols[j].setter(args,line,&args->cols[j],NULL); if ( ret < 0 ) error("fixme: Could not set %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); } } return has_overlap; } static int annotate_from_vcf(args_t *args, bcf1_t *line) { if ( !bcf_sr_has_line(args->files,1) ) return 0; int j; bcf1_t *aline = bcf_sr_get_line(args->files,1); for (j=0; jncols; j++) { if ( !args->cols[j].setter ) continue; if ( args->cols[j].setter(args,line,&args->cols[j],aline) ) error("fixme: Could not set %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); } return 1; } static int annotate_from_self(args_t *args, bcf1_t *line) { int j; for (j=0; jncols; j++) { if ( !args->cols[j].setter ) continue; if ( args->cols[j].setter(args,line,&args->cols[j],NULL) ) error("fixme: Could not set %s at %s:%"PRId64"\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),(int64_t) line->pos+1); } return 0; } static int annotate_line(args_t *args, bcf1_t *line) { args->current_rec = line; int i; for (i=0; inrm; i++) args->rm[i].handler(args, line, &args->rm[i]); int has_overlap = 0; if ( args->tgt_idx ) has_overlap = annotate_from_regidx(args,line); else if ( args->tgts ) has_overlap = annotate_from_tab(args,line); else if ( args->files->nreaders == 2 ) has_overlap = annotate_from_vcf(args,line); else if ( args->ncols ) has_overlap = annotate_from_self(args,line); if ( args->set_ids ) { args->tmpks.l = 0; convert_line(args->set_ids, line, &args->tmpks); if ( args->tmpks.l ) { int replace = 0; if ( args->set_ids_replace ) replace = 1; else if ( !line->d.id || (line->d.id[0]=='.' && !line->d.id[1]) ) replace = 1; if ( replace ) bcf_update_id(args->hdr_out,line,args->tmpks.s); } } if ( args->mark_sites ) { if ( !args->targets_fname ) has_overlap = 1; // ideally, we'd like to be far more general than this in future, see https://github.com/samtools/bcftools/issues/87 if ( args->mark_sites_logic==MARK_LISTED ) bcf_update_info_flag(args->hdr_out,line,args->mark_sites,NULL,has_overlap?1:0); else bcf_update_info_flag(args->hdr_out,line,args->mark_sites,NULL,has_overlap?0:1); } return has_overlap; } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Annotate and edit VCF/BCF files.\n"); fprintf(stderr, "Usage: bcftools annotate [options] VCF\n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -a, --annotations FILE VCF file or tabix-indexed FILE with annotations: CHR\\tPOS[\\tVALUE]+\n"); fprintf(stderr, " -c, --columns LIST List of columns in the annotation file, e.g. CHROM,POS,REF,ALT,-,INFO/TAG. See man page for details\n"); fprintf(stderr, " -C, --columns-file FILE Read -c columns from FILE, one name per row, with optional --merge-logic TYPE: NAME[ TYPE]\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " --force Continue despite parsing error (at your own risk!)\n"); fprintf(stderr, " -H, --header-line STR Header line which should be appended to the VCF header, can be given multiple times\n"); fprintf(stderr, " -h, --header-lines FILE Lines which should be appended to the VCF header\n"); fprintf(stderr, " -I, --set-id [+]FORMAT Set ID column using a `bcftools query`-like expression, see man page for details\n"); fprintf(stderr, " -i, --include EXPR Select sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -k, --keep-sites Leave -i/-e sites unchanged instead of discarding them\n"); fprintf(stderr, " -l, --merge-logic TAG:TYPE Merge logic for multiple overlapping regions (see man page for details), EXPERIMENTAL\n"); fprintf(stderr, " -m, --mark-sites [+-]TAG Add INFO/TAG flag to sites which are (\"+\") or are not (\"-\") listed in the -a file\n"); fprintf(stderr, " --min-overlap ANN:VCF Required overlap as a fraction of variant in the -a file (ANN), the VCF (:VCF), or reciprocal (ANN:VCF)\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " --pair-logic STR Matching records by , see man page for details [some]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in FILE\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " --rename-annots FILE Rename annotations: TYPE/old\\tnew, where TYPE is one of FILTER,INFO,FORMAT\n"); fprintf(stderr, " --rename-chrs FILE Rename sequences according to the mapping: old\\tnew\n"); fprintf(stderr, " -s, --samples [^]LIST Comma separated list of samples to annotate (or exclude with \"^\" prefix)\n"); fprintf(stderr, " -S, --samples-file [^]FILE File of samples to annotate (or exclude with \"^\" prefix)\n"); fprintf(stderr, " --single-overlaps Keep memory low by avoiding complexities arising from handling multiple overlapping intervals\n"); fprintf(stderr, " -x, --remove LIST List of annotations (e.g. ID,INFO/DP,FORMAT/DP,FILTER) to remove (or keep with \"^\" prefix). See man page for details\n"); fprintf(stderr, " --threads INT Number of extra output compression threads [0]\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Examples:\n"); fprintf(stderr, " http://samtools.github.io/bcftools/howtos/annotate.html\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfannotate(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->files = bcf_sr_init(); args->output_fname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->ref_idx = args->alt_idx = args->chr_idx = args->beg_idx = args->end_idx = -1; args->set_ids_replace = 1; args->match_id = -1; args->match_end = -1; args->clevel = -1; args->pair_logic = -1; int regions_is_file = 0; int regions_overlap = 1; static struct option loptions[] = { {"keep-sites",no_argument,NULL,'k'}, {"mark-sites",required_argument,NULL,'m'}, {"set-id",required_argument,NULL,'I'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"annotations",required_argument,NULL,'a'}, {"merge-logic",required_argument,NULL,'l'}, {"collapse",required_argument,NULL,2}, {"pair-logic",required_argument,NULL,2}, {"include",required_argument,NULL,'i'}, {"exclude",required_argument,NULL,'e'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,3}, {"remove",required_argument,NULL,'x'}, {"columns-file",required_argument,NULL,'C'}, {"columns",required_argument,NULL,'c'}, {"rename-annots",required_argument,NULL,11}, {"rename-chrs",required_argument,NULL,1}, {"header-lines",required_argument,NULL,'h'}, {"header-line",required_argument,NULL,'H'}, {"samples",required_argument,NULL,'s'}, {"samples-file",required_argument,NULL,'S'}, {"single-overlaps",no_argument,NULL,10}, {"min-overlap",required_argument,NULL,12}, {"no-version",no_argument,NULL,8}, {"force",no_argument,NULL,'f'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "h:H:?o:O:r:R:a:x:c:C:i:e:S:s:I:m:kl:fW::",loptions,NULL)) >= 0) { switch (c) { case 'f': args->force = 1; break; case 'k': args->keep_sites = 1; break; case 'm': args->mark_sites_logic = MARK_LISTED; if ( optarg[0]=='+' ) args->mark_sites = optarg+1; else if ( optarg[0]=='-' ) { args->mark_sites = optarg+1; args->mark_sites_logic = MARK_UNLISTED; } else args->mark_sites = optarg; break; case 'l': if ( args->merge_method_str.l ) kputc(',',&args->merge_method_str); kputs(optarg,&args->merge_method_str); break; case 'I': args->set_ids_fmt = optarg; break; case 's': args->sample_names = optarg; break; case 'S': args->sample_names = optarg; args->sample_is_file = 1; break; case 'c': args->columns = strdup(optarg); break; case 'C': args->columns = strdup(optarg); args->columns_is_file = 1; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'x': args->remove_annots = optarg; break; case 'a': args->targets_fname = optarg; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 'h': args->header_fname = optarg; break; case 'H': args->header_lines = dbuf_push(args->header_lines,strdup(optarg)); break; case 1 : args->rename_chrs = optarg; break; case 2 : if ( args->pair_logic==-1 ) args->pair_logic = 0; if ( !strcmp(optarg,"snps") ) args->pair_logic |= BCF_SR_PAIR_SNP_REF; else if ( !strcmp(optarg,"indels") ) args->pair_logic |= BCF_SR_PAIR_INDEL_REF; else if ( !strcmp(optarg,"both") ) args->pair_logic |= BCF_SR_PAIR_BOTH_REF; else if ( !strcmp(optarg,"any") ) args->pair_logic |= BCF_SR_PAIR_ANY; else if ( !strcmp(optarg,"all") ) args->pair_logic |= BCF_SR_PAIR_ANY; else if ( !strcmp(optarg,"some") ) args->pair_logic |= BCF_SR_PAIR_SOME; else if ( !strcmp(optarg,"none") ) args->pair_logic = BCF_SR_PAIR_EXACT; else if ( !strcmp(optarg,"exact") ) args->pair_logic = BCF_SR_PAIR_EXACT; else error("The --pair-logic string \"%s\" not recognised.\n", optarg); break; case 3 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 10 : args->single_overlaps = 1; break; case 11 : args->rename_annots = optarg; break; case 12 : args->min_overlap_str = optarg; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(args); } else fname = argv[optind]; if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_fname ) { htsFile *fp = hts_open(args->targets_fname,"r"); if ( !fp ) error("Failed to open %s\n", args->targets_fname); htsFormat type = *hts_get_format(fp); hts_close(fp); if ( type.format==vcf || type.format==bcf ) { args->tgts_is_vcf = 1; args->files->require_index = 1; bcf_sr_set_opt(args->files,BCF_SR_PAIR_LOGIC,args->pair_logic>=0 ? args->pair_logic : BCF_SR_PAIR_SOME); if ( args->min_overlap_str ) error("The --min-overlap option cannot be used when annotating from a VCF\n"); } } if ( args->min_overlap_str && args->single_overlaps ) error("The options --single-overlaps and --min-overlap cannot be combined\n"); if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); static int line_errcode_warned = 0; init_data(args); while ( bcf_sr_next_line(args->files) ) { if ( !bcf_sr_has_line(args->files,0) ) continue; bcf1_t *line = bcf_sr_get_line(args->files,0); if ( line->errcode ) { if ( !args->force ) error("Encountered an error, cannot proceed. Please check the error output above.\n" "If feeling adventurous, use the --force option. (At your own risk!)\n"); else if ( !line_errcode_warned ) { fprintf(stderr, "Warning: Encountered an error, proceeding only because --force was given.\n" " Note that this can result in a segfault or a silent corruption of the output file!\n"); line_errcode_warned = 1; line->errcode = 0; } } if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { if ( args->keep_sites && bcf_write1(args->out_fh, args->hdr_out, line)!=0 ) error("[%s] Error: failed to write to %s\n", __func__,args->output_fname); continue; } } int keep = annotate_line(args, line); if ( args->filter_ext && !args->keep_sites && !keep ) continue; if ( bcf_write1(args->out_fh, args->hdr_out, line)!=0 ) error("[%s] Error: failed to write to %s\n", __func__,args->output_fname); } destroy_data(args); bcf_sr_destroy(args->files); free(args); return 0; } bcftools-1.21/vcfbuf.c000066400000000000000000000665101467060157400147110ustar00rootroot00000000000000/* The MIT License Copyright (c) 2016-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "bcftools.h" #include "vcfbuf.h" #include "rbuf.h" typedef struct { double max[VCFBUF_LD_N]; int rand_missing, filter1; } ld_t; typedef struct { bcf1_t *rec; double af; unsigned int af_set:1, filter:1, idx:30; } vcfrec_t; #define PRUNE_MODE_MAX_AF 1 #define PRUNE_MODE_1ST 2 #define PRUNE_MODE_RAND 3 typedef struct { int max_sites, mvrec, mac, mfarr, mode; int *ac, *idx; float *farr; char *af_tag; vcfrec_t **vrec; } prune_t; #define MARK_OVERLAP 1 #define MARK_DUP 2 #define MARK_EXPR 3 #define MARK_MISSING_SCALAR 0 // actual value to use #define MARK_MISSING_MAX_DP 1 // max overlap_t.value scaled by INFO/DP // temporary internal structure for iterative overlap removal by mark_t.expr typedef struct { double value; // the sort value int rmme, idx; // mark for removal, index in vcfbuf_t.rbuf int dp; // with MARK_MISSING_MAX_DP, INFO/DP is used extrapolate missing QUAL kbitset_t *bset; // mark which records it overlaps with, given as 0-based indexes to vcfbuf_t.rbuf bcf1_t *rec; } overlap_t; typedef struct { // modes int mode; char *expr; // sites marked according to expr, returned to the caller via vcfbuf_get() rbuf_t rbuf; uint8_t *mark; int last; // MARK_OVERLAP int overlap_rid, overlap_end; // MARK_EXPR int nbuf; overlap_t *buf, **buf_ptr; int missing_expr; // the value to use when min(QUAL) encounters a missing value float missing_value; // the default missing value float max_qual; // with MARK_MISSING_MAX_DP int max_qual_dp; // int ntmpi; // temporary int array and the allocated memory int32_t *tmpi; } mark_t; struct _vcfbuf_t { int win, // maximum number of sites in the buffer, either number of sites (<0) or bp (<0) dummy; // the caller maintains the buffer via push/peek/flush bcf_hdr_t *hdr; vcfrec_t *vcf; rbuf_t rbuf; ld_t ld; prune_t prune; mark_t mark; enum { clean, dirty } status; }; vcfbuf_t *vcfbuf_init(bcf_hdr_t *hdr, int win) { vcfbuf_t *buf = (vcfbuf_t*) calloc(1,sizeof(vcfbuf_t)); buf->hdr = hdr; buf->win = win; buf->status = clean; buf->mark.overlap_rid = -1; int i; for (i=0; ild.max[i] = HUGE_VAL; rbuf_init(&buf->rbuf, 0); return buf; } void vcfbuf_destroy(vcfbuf_t *buf) { int i; for (i=0; irbuf.m; i++) if ( buf->vcf[i].rec ) bcf_destroy(buf->vcf[i].rec); free(buf->vcf); free(buf->prune.farr); free(buf->prune.vrec); free(buf->prune.ac); free(buf->prune.af_tag); free(buf->prune.idx); free(buf->mark.mark); free(buf->mark.expr); for (i=0; imark.nbuf; i++) kbs_destroy(buf->mark.buf[i].bset); free(buf->mark.buf); free(buf->mark.buf_ptr); free(buf->mark.tmpi); free(buf); } int vcfbuf_set(vcfbuf_t *buf, vcfbuf_opt_t key, ...) { va_list args; switch (key) { case LD_FILTER1: va_start(args, key); buf->ld.filter1 = va_arg(args,int); va_end(args); return 0; case LD_RAND_MISSING: va_start(args, key); buf->ld.rand_missing = va_arg(args,int); va_end(args); return 0; case LD_MAX_R2: va_start(args, key); buf->ld.max[VCFBUF_LD_IDX_R2] = va_arg(args,double); va_end(args); return 0; case LD_MAX_LD: va_start(args, key); buf->ld.max[VCFBUF_LD_IDX_LD] = va_arg(args,double); va_end(args); return 0; case LD_MAX_HD: va_start(args, key); buf->ld.max[VCFBUF_LD_IDX_HD] = va_arg(args,double); va_end(args); return 0; case VCFBUF_DUMMY: va_start(args, key); buf->dummy = va_arg(args,int); va_end(args); return 0; case PRUNE_NSITES: va_start(args, key); buf->prune.max_sites = va_arg(args,int); if ( !buf->prune.mode ) buf->prune.mode = PRUNE_MODE_MAX_AF; va_end(args); return 0; case PRUNE_NSITES_MODE: va_start(args, key); char *mode = va_arg(args,char*); va_end(args); if ( !strcasecmp(mode,"maxAF") ) buf->prune.mode = PRUNE_MODE_MAX_AF; else if ( !strcasecmp(mode,"1st") ) buf->prune.mode = PRUNE_MODE_1ST; else if ( !strcasecmp(mode,"rand") ) buf->prune.mode = PRUNE_MODE_RAND; else error("The mode \"%s\" is not recognised\n",mode); return 0; case PRUNE_AF_TAG: va_start(args, key); buf->prune.af_tag = strdup(va_arg(args,char*)); va_end(args); return 0; case MARK: va_start(args, key); buf->mark.expr = strdup(va_arg(args,char*)); if ( !strcasecmp(buf->mark.expr,"overlap") ) buf->mark.mode = MARK_OVERLAP; else if ( !strcasecmp(buf->mark.expr,"dup") ) buf->mark.mode = MARK_DUP; else buf->mark.mode = MARK_EXPR; va_end(args); return 0; case MARK_MISSING_EXPR: va_start(args, key); char *expr = va_arg(args,char*); if ( !strcasecmp(expr,"0") ) { buf->mark.missing_expr = MARK_MISSING_SCALAR; buf->mark.missing_value = 0; } else if ( !strcasecmp(expr,"DP") ) { if ( buf->mark.mode!=MARK_EXPR ) error("Only the combination of --mark 'min(QUAL)' with --missing DP is currently supported\n"); buf->mark.missing_expr = MARK_MISSING_MAX_DP; } else error("todo: MARK_MISSING_EXPR=%s\n",expr); va_end(args); return 0; } return 0; } void *vcfbuf_get(vcfbuf_t *buf, vcfbuf_opt_t key, ...) { va_list args; va_start(args, key); if ( key==MARK ) return &buf->mark.last; va_end(args); return NULL; } int vcfbuf_nsites(vcfbuf_t *buf) { return buf->rbuf.n; } bcf1_t *vcfbuf_push(vcfbuf_t *buf, bcf1_t *rec) { // make sure the caller is using the buffer correctly and calls vcfbuf_flush() // before placing next vcfbuf_push() call assert(buf->status!=dirty); if ( !buf->dummy ) buf->status = dirty; rbuf_expand0(&buf->rbuf, vcfrec_t, buf->rbuf.n+1, buf->vcf); int i = rbuf_append(&buf->rbuf); if ( !buf->vcf[i].rec ) buf->vcf[i].rec = bcf_init1(); bcf1_t *ret = buf->vcf[i].rec; buf->vcf[i].rec = rec; buf->vcf[i].af_set = 0; buf->vcf[i].filter = buf->ld.filter1; buf->ld.filter1 = 0; return ret; } bcf1_t *vcfbuf_peek(vcfbuf_t *buf, int idx) { buf->status = clean; int i = rbuf_kth(&buf->rbuf, idx); return i<0 ? NULL : buf->vcf[i].rec; } bcf1_t *vcfbuf_remove(vcfbuf_t *buf, int idx) { int i = rbuf_kth(&buf->rbuf, idx); if ( i<0 ) return NULL; bcf1_t *rec = buf->vcf[i].rec; rbuf_remove_kth(&buf->rbuf, vcfrec_t, idx, buf->vcf); return rec; } static int cmpvrec(const void *_a, const void *_b) { vcfrec_t *a = *((vcfrec_t**) _a); vcfrec_t *b = *((vcfrec_t**) _b); if ( a->af < b->af ) return -1; if ( a->af == b->af ) return 0; return 1; } static int cmpint_desc(const void *_a, const void *_b) { int a = *((int*)_a); int b = *((int*)_b); if ( a < b ) return 1; if ( a == b ) return 0; return -1; } static void _prune_sites(vcfbuf_t *buf, int flush_all) { int nbuf = flush_all ? buf->rbuf.n : buf->rbuf.n - 1; int nprune = nbuf - buf->prune.max_sites; int i,k,irec = 0; if ( buf->prune.mode==PRUNE_MODE_1ST ) { int eoff = flush_all ? 1 : 2; for (i=0; irbuf, vcfrec_t, buf->rbuf.n - eoff, buf->vcf); return; } if ( buf->prune.mode==PRUNE_MODE_RAND ) { int eoff = flush_all ? 0 : 1; for (i=0; irbuf.n - eoff) * hts_drand48(); rbuf_remove_kth(&buf->rbuf, vcfrec_t, j, buf->vcf); } return; } if ( nbuf > buf->prune.mvrec ) { buf->prune.idx = (int*) realloc(buf->prune.idx, nbuf*sizeof(int)); buf->prune.vrec = (vcfrec_t**) realloc(buf->prune.vrec, nbuf*sizeof(vcfrec_t*)); buf->prune.mvrec = nbuf; } // set allele frequency and prepare buffer for sorting for (i=-1; rbuf_next(&buf->rbuf,&i) && irecvcf[i].rec; if ( line->n_allele > buf->prune.mac ) { buf->prune.ac = (int*) realloc(buf->prune.ac, line->n_allele*sizeof(*buf->prune.ac)); buf->prune.mac = line->n_allele; } if ( !buf->vcf[i].af_set ) { buf->vcf[i].af = 0; if ( buf->prune.af_tag ) { if ( bcf_get_info_float(buf->hdr,line,buf->prune.af_tag,&buf->prune.farr, &buf->prune.mfarr) > 0 ) buf->vcf[i].af = buf->prune.farr[0]; } else if ( bcf_calc_ac(buf->hdr, line, buf->prune.ac, BCF_UN_INFO|BCF_UN_FMT) ) { int ntot = buf->prune.ac[0], nalt = 0; for (k=1; kn_allele; k++) nalt += buf->prune.ac[k]; buf->vcf[i].af = ntot ? (float)nalt/ntot : 0; } buf->vcf[i].af_set = 1; } buf->vcf[i].idx = irec; buf->prune.vrec[irec++] = &buf->vcf[i]; } // sort by allele frequency, low AF will be removed preferentially qsort(buf->prune.vrec, nbuf, sizeof(*buf->prune.vrec), cmpvrec); // sort the rbuf indexes to be pruned descendently so that j-th rbuf index // is removed before i-th index if iprune.idx[i] = buf->prune.vrec[i]->idx; qsort(buf->prune.idx, nprune, sizeof(int), cmpint_desc); for (i=0; irbuf, vcfrec_t, buf->prune.idx[i], buf->vcf); } static int mark_dup_can_flush_(vcfbuf_t *buf, int flush_all) { int flush = flush_all; mark_t *mark = &buf->mark; if ( buf->status==dirty ) { // a new site was just added by vcfbuf_push() rbuf_expand0(&mark->rbuf, uint8_t, buf->rbuf.n, mark->mark); int i = rbuf_append(&mark->rbuf); mark->mark[i] = 0; if ( buf->rbuf.n==1 ) goto flush; // there is at least one previous site, check if it's a duplicate int k1 = rbuf_kth(&buf->rbuf, -1); int k2 = rbuf_kth(&buf->rbuf, -2); vcfrec_t *rec1 = &buf->vcf[k1]; vcfrec_t *rec2 = &buf->vcf[k2]; int is_dup = 1; if ( rec1->rec->rid!=rec2->rec->rid ) is_dup = 0; else if ( rec1->rec->pos!=rec2->rec->pos ) is_dup = 0; if ( is_dup ) { // it is, mark the last two sites as duplicates int k1 = rbuf_kth(&mark->rbuf, -1); int k2 = rbuf_kth(&mark->rbuf, -2); mark->mark[k1] = 1; mark->mark[k2] = 1; goto flush; } // the last site is not a duplicate with the previous, all sites but the last one can be flushed flush = 1; } else if ( buf->rbuf.n > 1 ) flush = 1; flush: if ( !flush ) return 0; int i = rbuf_shift(&mark->rbuf); mark->last = mark->mark[i]; return 1; } static int mark_overlap_helper_(vcfbuf_t *buf, int flush_all) { if ( buf->status!=dirty ) return flush_all; int flush = flush_all; mark_t *mark = &buf->mark; // a new site was just added by vcfbuf_push() buf->status = clean; rbuf_expand0(&mark->rbuf, uint8_t, buf->rbuf.n, mark->mark); int i = rbuf_append(&mark->rbuf); mark->mark[i] = 0; // determine beg and end of the last record that was just added i = rbuf_last(&buf->rbuf); vcfrec_t *last = &buf->vcf[i]; if ( mark->overlap_rid != last->rec->rid ) mark->overlap_end = 0; int beg_pos = last->rec->pos; int end_pos = last->rec->pos + last->rec->rlen - 1; // Assuming left-aligned indels. In case it is a deletion, the real variant // starts one base after. If an insertion, the overlap with previous is zero int imin = last->rec->rlen; for (i=0; irec->n_allele; i++) { char *ref = last->rec->d.allele[0]; char *alt = last->rec->d.allele[i]; if ( *alt == '<' ) continue; // ignore symbolic alleles while ( *ref && *alt && nt_to_upper(*ref)==nt_to_upper(*alt) ) { ref++; alt++; } if ( imin > ref - last->rec->d.allele[0] ) imin = ref - last->rec->d.allele[0]; } if ( beg_pos <= mark->overlap_end ) { // the new site overlaps with the previous beg_pos += imin; if ( beg_pos > end_pos ) end_pos = beg_pos; } if ( buf->rbuf.n==1 ) { mark->overlap_rid = last->rec->rid; mark->overlap_end = end_pos; return flush; } if ( beg_pos <= mark->overlap_end ) { if ( mark->overlap_end < end_pos ) mark->overlap_end = end_pos; int k1 = rbuf_kth(&mark->rbuf, -1); int k2 = rbuf_kth(&mark->rbuf, -2); mark->mark[k1] = 1; mark->mark[k2] = 1; } else { if ( mark->overlap_end < end_pos ) mark->overlap_end = end_pos; flush = 1; } return flush; } static int mark_overlap_can_flush_(vcfbuf_t *buf, int flush_all) { int flush = flush_all; if ( buf->status==dirty ) flush = mark_overlap_helper_(buf,flush_all); else if ( buf->rbuf.n > 1 ) flush = 1; if ( !flush ) return 0; mark_t *mark = &buf->mark; int i = rbuf_shift(&mark->rbuf); mark->last = mark->mark[i]; return 1; } static int records_overlap(bcf1_t *a, bcf1_t *b) { if ( a->rid != b->rid ) return 0; if ( a->pos + a->rlen - 1 < b->pos ) return 0; return 1; } static int cmp_overlap_ptr_asc(const void *aptr, const void *bptr) { overlap_t *a = *((overlap_t**)aptr); overlap_t *b = *((overlap_t**)bptr); if ( a->value < b->value ) return -1; if ( a->value > b->value ) return 1; return 0; } static void mark_expr_missing_reset_(vcfbuf_t *buf) { buf->mark.max_qual = 0; buf->mark.max_qual_dp = 0; } static void mark_expr_missing_prep_(vcfbuf_t *buf, overlap_t *olap) { int nval = bcf_get_info_int32(buf->hdr,olap->rec,"DP",&buf->mark.tmpi,&buf->mark.ntmpi); if ( nval!=1 ) return; olap->dp = buf->mark.tmpi[0]; if ( bcf_float_is_missing(olap->rec->qual) ) return; if ( buf->mark.max_qual < olap->rec->qual ) { buf->mark.max_qual = olap->rec->qual; buf->mark.max_qual_dp = olap->dp; } } static void mark_expr_missing_set_(vcfbuf_t *buf, overlap_t *olap) { if ( !bcf_float_is_missing(olap->rec->qual) ) return; if ( !buf->mark.max_qual_dp ) return; // scale QUAL of the most confident variant in the overlap proportionally to the coverage // and use that to prioritize the records olap->value = buf->mark.max_qual * olap->dp / buf->mark.max_qual_dp; } static int mark_expr_can_flush_(vcfbuf_t *buf, int flush_all) { mark_t *mark = &buf->mark; if ( strcasecmp("min(QUAL)",mark->expr) ) error("Todo; at this time only min(QUAL) is supported\n"); int flush = flush_all; if ( buf->status==dirty ) { flush = mark_overlap_helper_(buf,flush_all); if ( !flush ) return 0; if ( mark->missing_expr==MARK_MISSING_MAX_DP ) mark_expr_missing_reset_(buf); // init overlaps, each overlap_t structure keeps a list of overlapping records, symmetrical size_t nori = mark->nbuf; hts_resize(overlap_t, buf->rbuf.n, &mark->nbuf, &mark->buf, HTS_RESIZE_CLEAR); hts_resize(overlap_t*, buf->rbuf.n, &nori, &mark->buf_ptr, HTS_RESIZE_CLEAR); int i; for (i=0; irbuf.n; i++) { overlap_t *oi = &mark->buf[i]; int j = rbuf_kth(&buf->rbuf, i); assert(j>=0); bcf1_t *rec = buf->vcf[j].rec; assert(rec); oi->rec = rec; // todo: other than QUAL values oi->value = bcf_float_is_missing(rec->qual) ? mark->missing_value : rec->qual; if ( mark->missing_expr==MARK_MISSING_MAX_DP ) mark_expr_missing_prep_(buf,oi); if ( oi->bset ) { kbs_resize(&oi->bset,buf->rbuf.n); kbs_clear(oi->bset); } else oi->bset = kbs_init(buf->rbuf.n); oi->idx = i; mark->buf_ptr[i] = oi; mark->mark[oi->idx] = 0; } int nolap = 0; for (i=0; irbuf.n; i++) { overlap_t *oi = &mark->buf[i]; if ( mark->missing_expr==MARK_MISSING_MAX_DP ) mark_expr_missing_set_(buf,oi); int j; for (j=i+1; jrbuf.n; j++) { overlap_t *oj = &mark->buf[j]; if ( !records_overlap(oi->rec,oj->rec) ) continue; kbs_insert(oi->bset,j); kbs_insert(oj->bset,i); nolap++; } } // sort according to the requested criteria, currently only min(QUAL) qsort(mark->buf_ptr,buf->rbuf.n,sizeof(*mark->buf_ptr),cmp_overlap_ptr_asc); // todo: other than min() // go through the list sorted by overlap_t.value, eg QUAL for (i=0; nolap && irbuf.n; i++) { kbitset_iter_t itr; overlap_t *oi = mark->buf_ptr[i]; kbs_start(&itr); int j; while ((j=kbs_next(oi->bset, &itr)) >= 0) { kbs_delete(oi->bset,j); assert(nolap); assert(kbs_exists(mark->buf[j].bset,oi->idx)); kbs_delete(mark->buf[j].bset,oi->idx); nolap--; } j = rbuf_kth(&mark->rbuf,oi->idx); mark->mark[j] = 1; } } else if ( buf->rbuf.n > 1 ) flush = 1; if ( !flush ) return 0; int i = rbuf_shift(&mark->rbuf); mark->last = mark->mark[i]; return 1; } bcf1_t *vcfbuf_flush(vcfbuf_t *buf, int flush_all) { int i,j; // nothing to do, no lines in the buffer if ( buf->rbuf.n==0 ) return NULL; // dummy mode, always flushing if ( buf->dummy ) goto ret; // pruning mode if ( buf->win ) { int can_flush = flush_all; i = rbuf_kth(&buf->rbuf, 0); // first j = rbuf_last(&buf->rbuf); // last if ( buf->vcf[i].rec->rid != buf->vcf[j].rec->rid ) can_flush = 1; else if ( buf->win > 0 ) { if ( buf->rbuf.n > buf->win ) can_flush = 1; } else if ( buf->win < 0 ) { if ( !(buf->vcf[i].rec->pos - buf->vcf[j].rec->pos > buf->win) ) can_flush = 1; } buf->status = clean; if ( !can_flush ) return NULL; if ( buf->prune.max_sites && buf->prune.max_sites < buf->rbuf.n ) _prune_sites(buf, flush_all); goto ret; } // overlaps and duplicates if ( buf->mark.mode ) { int can_flush = 0; if ( buf->mark.mode==MARK_OVERLAP ) { if ( mark_overlap_can_flush_(buf,flush_all) ) can_flush = 1; } else if ( buf->mark.mode==MARK_DUP ) { if ( mark_dup_can_flush_(buf,flush_all) ) can_flush = 1; } if ( buf->mark.mode==MARK_EXPR ) { if ( mark_expr_can_flush_(buf,flush_all) ) can_flush = 1; } buf->status = clean; if ( !can_flush ) return NULL; goto ret; } ret: buf->status = clean; i = rbuf_shift(&buf->rbuf); return buf->vcf[i].rec; } static double _estimate_af(int8_t *ptr, int size, int nvals, int nsamples) { int i,j, nref = 0, nalt = 0; for (i=0; in_sample!=brec->n_sample ) error("Different number of samples: %d vs %d\n",arec->n_sample,brec->n_sample); assert( arec->n_sample ); int i,j,igt = bcf_hdr_id2int(buf->hdr, BCF_DT_ID, "GT"); bcf_unpack(arec, BCF_UN_FMT); bcf_unpack(brec, BCF_UN_FMT); bcf_fmt_t *afmt = NULL, *bfmt = NULL; for (i=0; in_fmt; i++) if ( arec->d.fmt[i].id==igt ) { afmt = &arec->d.fmt[i]; break; } if ( !afmt ) return -1; // no GT tag for (i=0; in_fmt; i++) if ( brec->d.fmt[i].id==igt ) { bfmt = &brec->d.fmt[i]; break; } if ( !bfmt ) return -1; // no GT tag if ( afmt->n==0 ) return -1; // empty?! if ( bfmt->n==0 ) return -1; // empty?! if ( afmt->type!=BCF_BT_INT8 ) error("TODO: the GT fmt_type is not int8!\n"); if ( bfmt->type!=BCF_BT_INT8 ) error("TODO: the GT fmt_type is not int8!\n"); // Determine allele frequencies, this is to sample randomly missing genotypes double aaf = 0, baf = 0; if ( buf->ld.rand_missing ) { aaf = _estimate_af((int8_t*)afmt->p, afmt->size, afmt->n, arec->n_sample); baf = _estimate_af((int8_t*)bfmt->p, bfmt->size, bfmt->n, brec->n_sample); } // Calculate r2, lf, hd double nhd[] = {0,0,0,0,0,0,0,0,0}; double ab = 0, aa = 0, bb = 0, a = 0, b = 0; int nab = 0, ndiff = 0; int an_tot = 0, bn_tot = 0; for (i=0; in_sample; i++) { int8_t *aptr = (int8_t*) (afmt->p + i*afmt->size); int8_t *bptr = (int8_t*) (bfmt->p + i*bfmt->size); int adsg = 0, bdsg = 0; // dosages (0,1,2) at sites (a,b) int an = 0, bn = 0; // number of alleles at sites (a,b) for (j=0; jn; j++) { if ( aptr[j]==bcf_int8_vector_end ) break; if ( aptr[j]==bcf_gt_missing ) { if ( !buf->ld.rand_missing ) break; if ( hts_drand48() >= aaf ) adsg += 1; } else if ( bcf_gt_allele(aptr[j]) ) adsg += 1; an++; } for (j=0; jn; j++) { if ( bptr[j]==bcf_int8_vector_end ) break; if ( bptr[j]==bcf_gt_missing ) { if ( !buf->ld.rand_missing ) break; if ( hts_drand48() >= baf ) bdsg += 1; } else if ( bcf_gt_allele(bptr[j]) ) bdsg += 1; bn++; } if ( an && bn ) { an_tot += an; aa += adsg*adsg; a += adsg; bn_tot += bn; bb += bdsg*bdsg; b += bdsg; if ( adsg!=bdsg ) ndiff++; ab += adsg*bdsg; nab++; } if ( an==2 && bn==2 ) // for now only diploid genotypes { assert( adsg<=2 && bdsg<=2 ); nhd[ bdsg*3 + adsg ]++; } } if ( !nab ) return -1; // no data in common for the two sites double pa = a/an_tot; double pb = b/bn_tot; double cor; if ( !ndiff ) cor = 1; else { if ( aa == a*a/nab || bb == b*b/nab ) // zero variance, add small noise { aa += 1e-4; bb += 1e-4; ab += 1e-4; a += 1e-2; b += 1e-2; nab++; } cor = (ab - a*b/nab) / sqrt(aa - a*a/nab) / sqrt(bb - b*b/nab); } ld->val[VCFBUF_LD_IDX_R2] = cor * cor; // Lewontin's normalization of D. Also we cap at 1 as the calculation // can result in values bigger than 1 for high AFs. ld->val[VCFBUF_LD_IDX_LD] = cor * sqrt(pa*(1-pa)*pb*(1-pb)); double norm; if ( ld->val[VCFBUF_LD_IDX_LD] < 0 ) norm = -pa*pb > -(1-pa)*(1-pb) ? -pa*pb : -(1-pa)*(1-pb); else norm = pa*(1-pb) > (1-pa)*pb ? pa*(1-pb) : (1-pa)*pb; if ( norm ) ld->val[VCFBUF_LD_IDX_LD] = fabs(norm) > fabs(ld->val[VCFBUF_LD_IDX_LD]) ? ld->val[VCFBUF_LD_IDX_LD]/norm : 1; if ( !ld->val[VCFBUF_LD_IDX_LD] ) ld->val[VCFBUF_LD_IDX_LD] = fabs(ld->val[VCFBUF_LD_IDX_LD]); // avoid "-0" on output ld->val[VCFBUF_LD_IDX_HD] = (nhd[0] + nhd[1]/2. + nhd[3]/2. + nhd[4]/4.)*(nhd[4]/4. + nhd[5]/2. + nhd[7]/2. + nhd[8]) - (nhd[1]/2. + nhd[2] + nhd[4]/4. + nhd[5]/2.)*(nhd[3]/2. + nhd[4]/4. + nhd[6] + nhd[7]/2.); ld->val[VCFBUF_LD_IDX_HD] /= nab; ld->val[VCFBUF_LD_IDX_HD] /= nab+1; return 0; } int vcfbuf_ld(vcfbuf_t *buf, bcf1_t *rec, vcfbuf_ld_t *ld) { int ret = -1; if ( !buf->rbuf.n ) return ret; int j, i = buf->rbuf.f; // Relying on vcfbuf being properly flushed - all sites in the buffer // must come from the same chromosome if ( buf->vcf[i].rec->rid != rec->rid ) return ret; vcfbuf_ld_t tmp; for (j=0; jval[j] = -HUGE_VAL; ld->rec[j] = NULL; } for (i=-1; rbuf_next(&buf->rbuf,&i); ) { if ( buf->vcf[i].filter ) continue; if ( _calc_r2_ld(buf, buf->vcf[i].rec, rec, &tmp) < 0 ) continue; // missing genotypes int done = 0; for (j=0; jval[j] < tmp.val[j] ) { ld->val[j] = tmp.val[j]; ld->rec[j] = buf->vcf[i].rec; } if ( buf->ld.max[j] < tmp.val[j] ) done = 1; ret = 0; } if ( done ) return ret; } return ret; } bcftools-1.21/vcfbuf.h000066400000000000000000000134341467060157400147130ustar00rootroot00000000000000/* The MIT License Copyright (c) 2017-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Buffer VCF records and perform operations on the buffer */ #ifndef __VCFBUF_H__ #define __VCFBUF_H__ #include typedef struct _vcfbuf_t vcfbuf_t; // Modes of operation typedef enum { VCFBUF_DUMMY, // int {0,1}, the caller maintains the buffer via push/peek/flush, nothing is removed by vcfbuf // pruning PRUNE_NSITES, // int, leave max this many sites in the window PRUNE_NSITES_MODE, // char *, maxAF (keep sites with max AF), 1st (sites that come first), rand (pick randomly) PRUNE_AF_TAG, // char *, use this INFO/AF tag with VCFBUF_NSITES // duplicates and overlaps MARK, // w: char *, resolve overlaps by preferentially removing sites according to EXPR: // min(QUAL) .. remove sites with lowest QUAL until overlaps are resolved // overlap .. select all overlapping sites // dup .. select duplicate sites // r: use as // while ( (rec=vcfbuf_flush(buf,flush_all)) ) // { // int is_marked = vcfbuf_get_val(buf,int,MARK); // if ( is_marked ) do_something(rec); // } MARK_MISSING_EXPR, // char *, what to do when missing value are encountered with min(QUAL) // 0 .. set to 0 (the default) // DP .. scale max quality in the window proportionally to INFO/DP // LD related options LD_RAND_MISSING, // randomize rather than ignore missing genotypes LD_FILTER1, // exclude the next record inserted by vcfbuf_push() from LD analysis LD_MAX_R2, // If set, vcfbuf_ld() will stop at the first record that exceeds the R2, LD_MAX_LD, // LD, or HD threshold. When multiple are set, the OR logic is applied LD_MAX_HD, // } vcfbuf_opt_t; /** * vcfbuf_set() - set various options, see the vcfbuf_opt_t keys for the complete list * * Returns 0 if the call succeeded, or negative number on error. */ int vcfbuf_set(vcfbuf_t *buf, vcfbuf_opt_t key, ...); // returns 0 on success /** * vcfbuf_get() - get various options, see the vcfbuf_opt_t keys * vcfbuf_get_val() - wrapper for `vcfbuf_get()` to return typed value * * The former returns pointer to the memory area populated by the requested setting, * its type can be inferred from the vcfbuf_opt_t documentation. */ void *vcfbuf_get(vcfbuf_t *buf, vcfbuf_opt_t key, ...); #define vcfbuf_get_val(buf,type,key) (*(type*)vcfbuf_get(buf, key)) /* * vcfbuf_init() - init buffer * @win: number of sites (>0), bp (<0) */ vcfbuf_t *vcfbuf_init(bcf_hdr_t *hdr, int win); void vcfbuf_destroy(vcfbuf_t *buf); /* * vcfbuf_push() - push a new site for analysis. * * Note that vcfbuf_flush() or vcfbuf_peek() must be called before next site is pushed. */ bcf1_t *vcfbuf_push(vcfbuf_t *buf, bcf1_t *rec); /* * vcfbuf_peek() - return pointer to i-th record in the buffer but do not remove it from the buffer * @idx: 0-based index to buffered lines */ bcf1_t *vcfbuf_peek(vcfbuf_t *buf, int idx); /* * vcfbuf_remove() - return pointer to i-th record in the buffer and remove it from the buffer * @idx: 0-based index to buffered lines */ bcf1_t *vcfbuf_remove(vcfbuf_t *buf, int idx); /* * vcfbuf_flush() - returns the next record or NULL, depending on the mode of operation and * the content of the buffer * * @flush_all: 1 if no more vcfbuf_push() calls will follow, 0 otherwise */ bcf1_t *vcfbuf_flush(vcfbuf_t *buf, int flush_all); /* * vcfbuf_nsites() - return the number of sites in the buffer */ int vcfbuf_nsites(vcfbuf_t *buf); /* * vcfbuf_ld() - find records with maximum LD values or the values in first record that exceeds thresholds * set by vcfbuf_set_opt(..,LD_MAX*,..) * * Returns 0 on success or -1 if no values were filled. * * @val: will be filled with the values * .. correlation coefficient r-squared * .. Lewontin's D' (PMID: 19433632) * .. Ragsdale's \hat{D} (doi:10.1093/molbev/msz265) * @rec: corresponding positions or NULL if the value(s) has not been set */ #define VCFBUF_LD_N 3 #define VCFBUF_LD_IDX_R2 0 #define VCFBUF_LD_IDX_LD 1 #define VCFBUF_LD_IDX_HD 2 typedef struct { double val[VCFBUF_LD_N]; // r2, ld, hd bcf1_t *rec[VCFBUF_LD_N]; // record with max r2, ld, hd } vcfbuf_ld_t; int vcfbuf_ld(vcfbuf_t *buf, bcf1_t *rec, vcfbuf_ld_t *ld); #endif bcftools-1.21/vcfcall.c000066400000000000000000001406501467060157400150460ustar00rootroot00000000000000/* vcfcall.c -- SNP/indel variant calling from VCF/BCF. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "call.h" #include "prob1.h" #include "ploidy.h" #include "gvcf.h" #include "regidx.h" #include "vcfbuf.h" void error(const char *format, ...); #define CF_NO_GENO 1 #define CF_INS_MISSED (1<<1) #define CF_CCALL (1<<2) // (1<<3) // (1<<4) // (1<<5) #define CF_ACGT_ONLY (1<<6) #define CF_QCALL (1<<7) #define CF_ADJLD (1<<8) #define CF_NO_INDEL (1<<9) #define CF_ANNO_MAX (1<<10) #define CF_MCALL (1<<11) #define CF_PAIRCALL (1<<12) #define CF_QCNT (1<<13) #define CF_INDEL_ONLY (1<<14) typedef struct { tgt_als_t *als; int nmatch_als, ibuf; } rec_tgt_t; typedef struct { int flag; // combination of CF_* flags above int output_type, n_threads, record_cmd_line, clevel; htsFile *bcf_in, *out_fh; char *bcf_fname, *output_fname; char **samples; // for subsampling and ploidy int nsamples, *samples_map; // mapping from output sample names to original VCF char *regions, *targets; // regions to process int regions_is_file, targets_is_file, regions_overlap; regidx_t *tgt_idx; regitr_t *tgt_itr, *tgt_itr_prev, *tgt_itr_tmp; vcfbuf_t *vcfbuf; char *samples_fname; int samples_is_file; int *sample2sex; // mapping for ploidy. If negative, interpreted as -1*ploidy int *sex2ploidy, *sex2ploidy_prev, nsex; ploidy_t *ploidy; gvcf_t *gvcf; bcf1_t *missed_line; call_t aux; // parameters and temporary data kstring_t str; int argc; char **argv; char *index_fn; int write_index; // int flag, prior_type, n1, n_sub, *sublist, n_perm; // uint32_t *trio_aux; // char *prior_file, **subsam; // uint8_t *ploidy; // double theta, pref, indel_frac, min_smpl_frac, min_lrt; // Permutation tests // int n_perm, *seeds; // double min_perm_p; // void *bed; } args_t; static char **add_sample(void *name2idx, char **lines, int *nlines, int *mlines, char *name, char sex, int *ith) { int ret = khash_str2int_get(name2idx, name, ith); if ( ret==0 ) return lines; hts_expand(char*,(*nlines+1),*mlines,lines); int len = strlen(name); lines[*nlines] = (char*) malloc(len+3); memcpy(lines[*nlines],name,len); lines[*nlines][len] = ' '; lines[*nlines][len+1] = sex; lines[*nlines][len+2] = 0; *ith = *nlines; (*nlines)++; khash_str2int_set(name2idx, strdup(name), *ith); return lines; } typedef struct { const char *alias, *about, *ploidy; } ploidy_predef_t; static ploidy_predef_t ploidy_predefs[] = { { .alias = "GRCh37", .about = "Human Genome reference assembly GRCh37 / hg19", .ploidy = "X 1 60000 M 1\n" "X 2699521 154931043 M 1\n" "Y 1 59373566 M 1\n" "Y 1 59373566 F 0\n" "MT 1 16569 M 1\n" "MT 1 16569 F 1\n" "chrX 1 60000 M 1\n" "chrX 2699521 154931043 M 1\n" "chrY 1 59373566 M 1\n" "chrY 1 59373566 F 0\n" "chrM 1 16569 M 1\n" "chrM 1 16569 F 1\n" "* * * M 2\n" "* * * F 2\n" }, { .alias = "GRCh38", .about = "Human Genome reference assembly GRCh38 / hg38", .ploidy = "X 1 9999 M 1\n" "X 2781480 155701381 M 1\n" "Y 1 57227415 M 1\n" "Y 1 57227415 F 0\n" "MT 1 16569 M 1\n" "MT 1 16569 F 1\n" "chrX 1 9999 M 1\n" "chrX 2781480 155701381 M 1\n" "chrY 1 57227415 M 1\n" "chrY 1 57227415 F 0\n" "chrM 1 16569 M 1\n" "chrM 1 16569 F 1\n" "* * * M 2\n" "* * * F 2\n" }, { .alias = "X", .about = "Treat male samples as haploid and female as diploid regardless of the chromosome name", .ploidy = "* * * M 1\n" "* * * F 2\n" }, { .alias = "Y", .about = "Treat male samples as haploid and female as no-copy, regardless of the chromosome name", .ploidy = "* * * M 1\n" "* * * F 0\n" }, { .alias = "1", .about = "Treat all samples as haploid", .ploidy = "* * * * 1\n" }, { .alias = "2", .about = "Treat all samples as diploid", .ploidy = "* * * * 2\n" }, { .alias = NULL, .about = NULL, .ploidy = NULL, } }; // only 5 columns are required and the first is ignored: // ignored,sample,father(or 0),mother(or 0),sex(1=M,2=F) static char **parse_ped_samples(call_t *call, char **vals, int nvals, int *nsmpl) { int i, j, mlines = 0, nlines = 0; kstring_t str = {0,0,0}, fam_str = {0,0,0}; void *name2idx = khash_str2int_init(); char **lines = NULL; for (i=0; infams++; hts_expand(family_t, call->nfams, call->mfams, call->fams); family_t *fam = &call->fams[call->nfams-1]; fam_str.l = 0; ksprintf(&fam_str,"father=%s, mother=%s, child=%s", col_ends[1]+1,col_ends[2]+1,col_ends[0]+1); fam->name = strdup(fam_str.s); if ( !khash_str2int_has_key(name2idx, col_ends[1]+1) ) lines = add_sample(name2idx, lines, &nlines, &mlines, col_ends[1]+1, 'M', &fam->sample[FATHER]); if ( !khash_str2int_has_key(name2idx, col_ends[2]+1) ) lines = add_sample(name2idx, lines, &nlines, &mlines, col_ends[2]+1, 'F', &fam->sample[MOTHER]); khash_str2int_get(name2idx, col_ends[0]+1, &fam->sample[CHILD]); khash_str2int_get(name2idx, col_ends[1]+1, &fam->sample[FATHER]); khash_str2int_get(name2idx, col_ends[2]+1, &fam->sample[MOTHER]); } } free(str.s); free(fam_str.s); khash_str2int_destroy_free(name2idx); if ( i!=nvals ) return NULL; // not a ped file *nsmpl = nlines; return lines; } /* * Reads sample names and their ploidy (optional) from a file. * Alternatively, if no such file exists, the file name is interpreted * as a comma-separated list of samples. When ploidy is not present, * the default ploidy 2 is assumed. */ static void set_samples(args_t *args, const char *fn, int is_file) { int i, nlines; char **lines = hts_readlist(fn, is_file, &nlines); if ( !lines ) error("Could not read the file: %s\n", fn); int nsmpls; char **smpls = parse_ped_samples(&args->aux, lines, nlines, &nsmpls); if ( smpls ) { for (i=0; isamples_map = (int*) malloc(sizeof(int)*bcf_hdr_nsamples(args->aux.hdr)); // for subsetting args->sample2sex = (int*) malloc(sizeof(int)*bcf_hdr_nsamples(args->aux.hdr)); int dflt_sex_id = ploidy_nsex(args->ploidy) - 1; for (i=0; iaux.hdr); i++) args->sample2sex[i] = dflt_sex_id; int *old2new = (int*) malloc(sizeof(int)*bcf_hdr_nsamples(args->aux.hdr)); for (i=0; iaux.hdr); i++) old2new[i] = -1; int nsmpl = 0, map_needed = 0; for (i=0; iaux.hdr, BCF_DT_SAMPLE, ss); if ( ismpl < 0 ) { fprintf(stderr,"Warning: No such sample in the VCF: %s\n",ss); continue; } if ( old2new[ismpl] != -1 ) { fprintf(stderr,"Warning: The sample is listed multiple times: %s\n",ss); continue; } ss = se+(x != '\0'); while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) ss = "2"; // default ploidy se = ss; while ( *se && !isspace(*se) ) se++; if ( se==ss ) { *xptr = x; error("Could not parse: \"%s\"\n", lines[i]); } if ( ss[1]==0 && (ss[0]=='0' || ss[0]=='1' || ss[0]=='2') ) args->sample2sex[nsmpl] = -1*(ss[0]-'0'); else args->sample2sex[nsmpl] = ploidy_add_sex(args->ploidy, ss); if ( ismpl!=nsmpl ) map_needed = 1; args->samples_map[nsmpl] = ismpl; old2new[ismpl] = nsmpl; nsmpl++; } for (i=0; iaux.nfams; i++) { int j, nmiss = 0; family_t *fam = &args->aux.fams[i]; for (j=0; j<3; j++) { fam->sample[i] = old2new[fam->sample[i]]; if ( fam->sample[i]<0 ) nmiss++; } assert( nmiss==0 || nmiss==3 ); } free(old2new); if ( !map_needed ) { free(args->samples_map); args->samples_map = NULL; } args->nsamples = nsmpl; args->samples = lines; } static void init_missed_line(args_t *args) { int i; for (i=0; iaux.hdr); i++) { args->aux.gts[i*2] = bcf_gt_missing; args->aux.gts[i*2+1] = bcf_int32_vector_end; } args->missed_line = bcf_init1(); bcf_update_genotypes(args->aux.hdr, args->missed_line, args->aux.gts, 2*bcf_hdr_nsamples(args->aux.hdr)); bcf_float_set_missing(args->missed_line->qual); } static int tgt_parse(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) { char *ss = (char*) line; while ( *ss && isspace(*ss) ) ss++; if ( !*ss ) { fprintf(stderr,"Could not parse the line: %s\n", line); return -2; } if ( *ss=='#' ) return -1; // skip comments char *se = ss; while ( *se && !isspace(*se) ) se++; *chr_beg = ss; *chr_end = se-1; if ( !*se ) { fprintf(stderr,"Could not parse the line: %s\n", line); return -2; } ss = se+1; *beg = strtod(ss, &se); if ( ss==se ) { fprintf(stderr,"Could not parse tab line: %s\n", line); return -2; } if ( *beg==0 ) { fprintf(stderr,"Could not parse tab line, expected 1-based coordinate: %s\n", line); return -2; } (*beg)--; *end = *beg; if ( !usr ) return 0; // allele information not required ss = se+1; tgt_als_t *als = (tgt_als_t*)payload; als->used = 0; als->n = 0; als->allele = NULL; while ( *ss ) { se = ss; while ( *se && *se!=',' && !isspace(*se) ) se++; als->n++; als->allele = (char**)realloc(als->allele,als->n*sizeof(*als->allele)); als->allele[als->n-1] = (char*)malloc(se-ss+1); memcpy(als->allele[als->n-1],ss,se-ss); als->allele[als->n-1][se-ss] = 0; ss = se+1; if ( !*se || isspace(*se) ) break; } if ( als->n<2 ) error("Unable to parse the -T file; expected CHROM\\tPOS\\tREF,ALT with -C alleles but found instead:\n\t%s\n",line); return 0; } static void tgt_free(void *payload) { tgt_als_t *als = (tgt_als_t*)payload; int i; for (i=0; in; i++) free(als->allele[i]); free(als->allele); } static void tgt_flush_region(args_t *args, char *chr, uint32_t beg, uint32_t end) { if ( !regidx_overlap(args->tgt_idx, chr,beg,end,args->tgt_itr_tmp) ) return; while ( regitr_overlap(args->tgt_itr_tmp) ) { if ( args->tgt_itr_tmp->beg < beg ) continue; tgt_als_t *tgt_als = ®itr_payload(args->tgt_itr_tmp,tgt_als_t); if ( tgt_als->used ) continue; args->missed_line->rid = bcf_hdr_name2id(args->aux.hdr,chr); args->missed_line->pos = args->tgt_itr_tmp->beg; bcf_unpack(args->missed_line,BCF_UN_ALL); bcf_update_alleles(args->aux.hdr, args->missed_line, (const char**)tgt_als->allele, tgt_als->n); tgt_als->used = 1; if ( bcf_write1(args->out_fh, args->aux.hdr, args->missed_line)!=0 ) error("[%s] Error: failed to write to %s\n", __func__,args->output_fname); } } static void tgt_flush(args_t *args, bcf1_t *rec) { if ( rec ) { char *chr = (char*)bcf_seqname(args->aux.hdr,rec); if ( !args->tgt_itr_prev ) // first record tgt_flush_region(args,chr,0,rec->pos-1); else if ( strcmp(chr,args->tgt_itr_prev->seq) ) // first record on a new chromosome { tgt_flush_region(args,args->tgt_itr_prev->seq,args->tgt_itr_prev->beg+1,REGIDX_MAX); tgt_flush_region(args,chr,0,rec->pos-1); } else // another record on the same chromosome tgt_flush_region(args,args->tgt_itr_prev->seq,args->tgt_itr_prev->beg,rec->pos-1); } else { // flush everything if ( args->tgt_itr_prev ) tgt_flush_region(args,args->tgt_itr_prev->seq,args->tgt_itr_prev->beg,REGIDX_MAX); int i, nchr = 0; char **chr = regidx_seq_names(args->tgt_idx, &nchr); for (i=0; i" is not present at indels sites and there are no other symbolic alleles than <*> if ( als[1][0]=='<' ) return 0; int i; for (i=0; ivcfbuf ) { while ( bcf_sr_next_line(args->aux.srs) ) { rec = args->aux.srs->readers[0].buffer[0]; if ( args->aux.srs->errnum || rec->errcode ) error("Error: could not parse the input VCF\n"); if ( args->tgt_idx ) { if ( !regidx_overlap(args->tgt_idx, bcf_seqname(args->aux.hdr,rec),rec->pos,rec->pos,args->tgt_itr) ) continue; // For backward compatibility: require the exact position, not an interval overlap int pos_match = 0; while ( regitr_overlap(args->tgt_itr) ) { if ( args->tgt_itr->beg != rec->pos ) continue; pos_match = 1; break; } if ( !pos_match ) continue; } if ( args->samples_map ) bcf_subset(args->aux.hdr, rec, args->nsamples, args->samples_map); bcf_unpack(rec, BCF_UN_STR); return rec; } return NULL; } // If we are here,-C alleles was given and vcfbuf and tgt_idx are set // Fill the buffer with duplicate lines int vcfbuf_full = 1; int nbuf = vcfbuf_nsites(args->vcfbuf); bcf1_t *rec0 = NULL, *recN = NULL; if ( nbuf==0 ) vcfbuf_full = 0; else if ( nbuf==1 ) { vcfbuf_full = 0; rec0 = vcfbuf_peek(args->vcfbuf, 0); } else { rec0 = vcfbuf_peek(args->vcfbuf, 0); recN = vcfbuf_peek(args->vcfbuf, nbuf-1); if ( rec0->rid == recN->rid && rec0->pos == recN->pos ) vcfbuf_full = 0; } if ( !vcfbuf_full ) { while ( bcf_sr_next_line(args->aux.srs) ) { rec = args->aux.srs->readers[0].buffer[0]; if ( args->aux.srs->errnum || rec->errcode ) error("Error: could not parse the input VCF\n"); if ( !regidx_overlap(args->tgt_idx, bcf_seqname(args->aux.hdr,rec),rec->pos,rec->pos,args->tgt_itr) ) continue; // as above: require the exact position, not an interval overlap int exact_match = 0; while ( regitr_overlap(args->tgt_itr) ) { if ( args->tgt_itr->beg != rec->pos ) continue; exact_match = 1; break; } if ( !exact_match ) continue; if ( args->samples_map ) bcf_subset(args->aux.hdr, rec, args->nsamples, args->samples_map); bcf_unpack(rec, BCF_UN_STR); if ( !rec0 ) rec0 = rec; recN = rec; args->aux.srs->readers[0].buffer[0] = vcfbuf_push(args->vcfbuf, rec); if ( rec0->rid!=recN->rid || rec0->pos!=recN->pos ) break; } } nbuf = vcfbuf_nsites(args->vcfbuf); int n, i,j; for (n=nbuf; n>1; n--) { recN = vcfbuf_peek(args->vcfbuf, n-1); if ( rec0->rid==recN->rid && rec0->pos==recN->pos ) break; } if ( n==0 ) { assert( !nbuf ); return NULL; } // Find the VCF and tab record with the best matching combination of alleles, prioritize // records of the same type (snp vs indel) rec_tgt_t rec_tgt; memset(&rec_tgt,0,sizeof(rec_tgt)); regidx_overlap(args->tgt_idx, bcf_seqname(args->aux.hdr,rec0),rec0->pos,rec0->pos,args->tgt_itr); regitr_t *tmp_itr = regitr_init(args->tgt_idx); for (i=0; itgt_itr); rec = vcfbuf_peek(args->vcfbuf, i); int rec_indel = is_indel(rec->n_allele, rec->d.allele) ? 1 : -1; while ( regitr_overlap(tmp_itr) ) { if ( tmp_itr->beg != rec->pos ) continue; tgt_als_t *als = ®itr_payload(tmp_itr,tgt_als_t); if ( als->used ) continue; int nmatch_als = 0; vcmp_t *vcmp = vcmp_init(); int ret = vcmp_set_ref(vcmp, rec->d.allele[0], als->allele[0]); if ( ret==0 ) { nmatch_als++; if ( rec->n_allele > 1 && als->n > 1 ) { for (j=1; jn; j++) { if ( vcmp_find_allele(vcmp, rec->d.allele+1, rec->n_allele-1, als->allele[j])>=0 ) nmatch_als++; } } } int als_indel = is_indel(als->n, als->allele) ? 1 : -1; nmatch_als *= rec_indel*als_indel; if ( nmatch_als > rec_tgt.nmatch_als || !rec_tgt.als ) { rec_tgt.nmatch_als = nmatch_als; rec_tgt.als = als; rec_tgt.ibuf = i; } vcmp_destroy(vcmp); } } regitr_destroy(tmp_itr); args->aux.tgt_als = rec_tgt.als; if ( rec_tgt.als ) rec_tgt.als->used = 1; rec = vcfbuf_remove(args->vcfbuf, rec_tgt.ibuf); return rec; } static void init_data(args_t *args) { args->aux.srs = bcf_sr_init(); // Open files for input and output, initialize structures if ( args->targets ) { args->tgt_idx = regidx_init(args->targets, tgt_parse, args->aux.flag&CALL_CONSTR_ALLELES ? tgt_free : (regidx_free_f) NULL, sizeof(tgt_als_t), args->aux.flag&CALL_CONSTR_ALLELES ? args : NULL); args->tgt_itr = regitr_init(args->tgt_idx); args->tgt_itr_tmp = regitr_init(args->tgt_idx); } if ( args->regions ) { bcf_sr_set_opt(args->aux.srs,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->aux.srs, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions); } if ( !bcf_sr_add_reader(args->aux.srs, args->bcf_fname) ) error("Failed to read from %s: %s\n", !strcmp("-",args->bcf_fname)?"standard input":args->bcf_fname,bcf_sr_strerror(args->aux.srs->errnum)); args->aux.hdr = bcf_sr_get_header(args->aux.srs,0); int i; if ( args->samples_fname ) { set_samples(args, args->samples_fname, args->samples_is_file); if ( args->aux.flag&CALL_CONSTR_TRIO ) { if ( 3*args->aux.nfams!=args->nsamples ) error("Expected only trios in %s, sorry!\n", args->samples_fname); fprintf(stderr,"Detected %d samples in %d trio families\n", args->nsamples,args->aux.nfams); } } if ( args->ploidy ) { args->nsex = ploidy_nsex(args->ploidy); args->sex2ploidy = (int*) calloc(args->nsex,sizeof(int)); args->sex2ploidy_prev = (int*) calloc(args->nsex,sizeof(int)); if ( !args->nsamples ) { args->nsamples = bcf_hdr_nsamples(args->aux.hdr); args->sample2sex = (int*) malloc(sizeof(int)*args->nsamples); for (i=0; insamples; i++) args->sample2sex[i] = args->nsex - 1; } } if ( args->nsamples ) { args->aux.ploidy = (uint8_t*) malloc(args->nsamples); for (i=0; insamples; i++) args->aux.ploidy[i] = ploidy_max(args->ploidy); for (i=0; insex; i++) args->sex2ploidy_prev[i] = ploidy_max(args->ploidy); for (i=0; insamples; i++) if ( args->sample2sex[i] >= args->nsex ) args->sample2sex[i] = args->nsex - 1; } if ( args->gvcf ) { int id = bcf_hdr_id2int(args->aux.hdr,BCF_DT_ID,"DP"); if ( id<0 || !bcf_hdr_idinfo_exists(args->aux.hdr,BCF_HL_FMT,id) ) error("--gvcf output mode requires FORMAT/DP tag, which is not present in the input header\n"); gvcf_update_header(args->gvcf, args->aux.hdr); } if ( args->samples_map ) { args->aux.hdr = bcf_hdr_subset(bcf_sr_get_header(args->aux.srs,0), args->nsamples, args->samples, args->samples_map); if ( !args->aux.hdr ) error("Error occurred while subsetting samples\n"); for (i=0; insamples; i++) if ( args->samples_map[i]<0 ) error("No such sample: %s\n", args->samples[i]); if ( !bcf_hdr_nsamples(args->aux.hdr) ) error("No matching sample found\n"); } else { args->aux.hdr = bcf_hdr_dup(bcf_sr_get_header(args->aux.srs,0)); if ( args->samples ) { for (i=0; insamples; i++) if ( bcf_hdr_id2int(args->aux.hdr,BCF_DT_SAMPLE,args->samples[i])<0 ) error("No such sample: %s\n", args->samples[i]); } } if ( args->aux.flag & CALL_CONSTR_ALLELES ) { args->vcfbuf = vcfbuf_init(args->aux.hdr, 0); vcfbuf_set(args->vcfbuf,VCFBUF_DUMMY,1); } char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Error: cannot write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); if ( args->flag & CF_QCALL ) return; if ( args->flag & CF_MCALL ) mcall_init(&args->aux); if ( args->flag & CF_CCALL ) ccall_init(&args->aux); bcf_hdr_remove(args->aux.hdr, BCF_HL_INFO, "QS"); bcf_hdr_remove(args->aux.hdr, BCF_HL_INFO, "I16"); if (args->record_cmd_line) bcf_hdr_append_version(args->aux.hdr, args->argc, args->argv, "bcftools_call"); if ( bcf_hdr_write(args->out_fh, args->aux.hdr)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->aux.hdr,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); if ( args->flag&CF_INS_MISSED ) init_missed_line(args); } static void destroy_data(args_t *args) { if ( args->vcfbuf ) vcfbuf_destroy(args->vcfbuf); if ( args->tgt_idx ) { regidx_destroy(args->tgt_idx); regitr_destroy(args->tgt_itr); regitr_destroy(args->tgt_itr_tmp); if ( args->tgt_itr_prev ) regitr_destroy(args->tgt_itr_prev); } if ( args->flag & CF_CCALL ) ccall_destroy(&args->aux); else if ( args->flag & CF_MCALL ) mcall_destroy(&args->aux); else if ( args->flag & CF_QCALL ) qcall_destroy(&args->aux); int i; if ( args->samples ) { for (i=0; insamples; i++) free(args->samples[i]); } if ( args->aux.fams ) { for (i=0; iaux.nfams; i++) free(args->aux.fams[i].name); free(args->aux.fams); } if ( args->missed_line ) bcf_destroy(args->missed_line); ploidy_destroy(args->ploidy); free(args->sex2ploidy); free(args->sex2ploidy_prev); free(args->samples); free(args->samples_map); free(args->sample2sex); free(args->aux.ploidy); free(args->str.s); if ( args->gvcf ) gvcf_destroy(args->gvcf); bcf_hdr_destroy(args->aux.hdr); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); bcf_sr_destroy(args->aux.srs); } void parse_novel_rate(args_t *args, const char *str) { if ( sscanf(str,"%le,%le,%le",&args->aux.trio_Pm_SNPs,&args->aux.trio_Pm_del,&args->aux.trio_Pm_ins)==3 ) // explicit for all { args->aux.trio_Pm_SNPs = 1 - args->aux.trio_Pm_SNPs; args->aux.trio_Pm_del = 1 - args->aux.trio_Pm_del; args->aux.trio_Pm_ins = 1 - args->aux.trio_Pm_ins; } else if ( sscanf(str,"%le,%le",&args->aux.trio_Pm_SNPs,&args->aux.trio_Pm_del)==2 ) // dynamic for indels { args->aux.trio_Pm_SNPs = 1 - args->aux.trio_Pm_SNPs; args->aux.trio_Pm_ins = -1; // negative value for dynamic calculation } else if ( sscanf(str,"%le",&args->aux.trio_Pm_SNPs)==1 ) // same for all { args->aux.trio_Pm_SNPs = 1 - args->aux.trio_Pm_SNPs; args->aux.trio_Pm_del = -1; args->aux.trio_Pm_ins = -1; } else error("Could not parse --novel-rate %s\n", str); } static void list_annotations(FILE *fp) { fprintf(fp, "\n" "Optional INFO annotations available with -m (\"INFO/\" prefix is optional):\n" " INFO/PV4 .. P-values for strand bias, baseQ bias, mapQ bias and tail distance bias (Number=4,Type=Float)\n" "\n" "Optional FORMAT annotations available with -m (\"FORMAT/\" prefix is optional):\n" " FORMAT/GQ .. Phred-scaled genotype quality (Number=1,Type=Integer)\n" " FORMAT/GP .. Phred-scaled genotype posterior probabilities (Number=G,Type=Float)\n" "\n"); } static int parse_output_tags(const char *str) { int flag = 0; const char *ss = str; while ( *ss ) { const char *se = ss; while ( *se && *se!=',' ) se++; if ( !strncasecmp(ss,"GQ",se-ss) || !strncasecmp(ss,"FORMAT/GQ",se-ss) || !strncasecmp(ss,"FMT/GQ",se-ss) ) flag |= CALL_FMT_GQ; else if ( !strncasecmp(ss,"GP",se-ss) || !strncasecmp(ss,"FORMAT/GP",se-ss) || !strncasecmp(ss,"FMT/GP",se-ss) ) flag |= CALL_FMT_GP; else if ( !strncasecmp(ss,"PV4",se-ss) || !strncasecmp(ss,"INFO/PV4",se-ss) ) flag |= CALL_FMT_PV4; else { fprintf(stderr,"Could not parse \"%s\"\n", str); exit(1); } if ( !*se ) break; ss = se + 1; } return flag; } static void set_ploidy(args_t *args, bcf1_t *rec) { ploidy_query(args->ploidy,(char*)bcf_seqname(args->aux.hdr,rec),rec->pos,args->sex2ploidy,NULL,NULL); int i; for (i=0; insex; i++) if ( args->sex2ploidy[i]!=args->sex2ploidy_prev[i] ) break; if ( i==args->nsex ) return; // ploidy same as previously for (i=0; insamples; i++) { if ( args->sample2sex[i]<0 ) args->aux.ploidy[i] = -1*args->sample2sex[i]; else args->aux.ploidy[i] = args->sex2ploidy[args->sample2sex[i]]; } int *tmp = args->sex2ploidy; args->sex2ploidy = args->sex2ploidy_prev; args->sex2ploidy_prev = tmp; } ploidy_t *init_ploidy(char *alias) { const ploidy_predef_t *pld = ploidy_predefs; int detailed = 0, len = strlen(alias); if ( alias[len-1]=='?' ) { detailed = 1; alias[len-1] = 0; } while ( pld->alias && strcasecmp(alias,pld->alias) ) pld++; if ( !pld->alias ) { fprintf(stderr,"\nPRE-DEFINED PLOIDY FILES\n\n"); fprintf(stderr," * Columns are: CHROM,FROM,TO,SEX,PLOIDY\n"); fprintf(stderr," * Coordinates are 1-based inclusive.\n"); fprintf(stderr," * A '*' means any value not otherwise defined.\n\n"); pld = ploidy_predefs; while ( pld->alias ) { fprintf(stderr,"%s\n .. %s\n\n", pld->alias,pld->about); if ( detailed ) fprintf(stderr,"%s\n", pld->ploidy); pld++; } fprintf(stderr,"Run as --ploidy (e.g. --ploidy GRCh37).\n"); fprintf(stderr,"To see the detailed ploidy definition, append a question mark (e.g. --ploidy GRCh37?).\n"); fprintf(stderr,"\n"); exit(-1); } else if ( detailed ) { fprintf(stderr,"%s", pld->ploidy); exit(-1); } return ploidy_init_string(pld->ploidy,2); } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: SNP/indel variant calling from VCF/BCF. To be used in conjunction with bcftools mpileup.\n"); fprintf(stderr, " This command replaces the former \"bcftools view\" caller. Some of the original\n"); fprintf(stderr, " functionality has been temporarily lost in the process of transition to htslib,\n"); fprintf(stderr, " but will be added back on popular demand. The original calling model can be\n"); fprintf(stderr, " invoked with the -c option.\n"); fprintf(stderr, "Usage: bcftools call [options] \n"); fprintf(stderr, "\n"); fprintf(stderr, "File format options:\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type b|u|z|v Output type: 'b' compressed BCF; 'u' uncompressed BCF; 'z' compressed VCF; 'v' uncompressed VCF [v]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " --ploidy ASSEMBLY[?] Predefined ploidy, 'list' to print available settings, append '?' for details [2]\n"); fprintf(stderr, " --ploidy-file FILE Space/tab-delimited list of CHROM,FROM,TO,SEX,PLOIDY\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples LIST List of samples to include [all samples]\n"); fprintf(stderr, " -S, --samples-file FILE PED file or a file with an optional column with sex (see man page for details) [all samples]\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --threads INT Use multithreading with INT worker threads [0]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Input/output options:\n"); fprintf(stderr, " -A, --keep-alts Keep all possible alternate alleles at variant sites\n"); fprintf(stderr, " -*, --keep-unseen-allele Keep the unobserved allele <*> or \n"); fprintf(stderr, " -a, --annotate LIST Optional tags to output (lowercase allowed); '?' to list available tags\n"); fprintf(stderr, " -F, --prior-freqs AN,AC Use prior allele frequencies, determined from these pre-filled tags\n"); fprintf(stderr, " -G, --group-samples FILE|- Group samples by population (file with \"sample\\tgroup\") or \"-\" for single-sample calling.\n"); fprintf(stderr, " This requires FORMAT/QS or other Number=R,Type=Integer tag such as FORMAT/AD\n"); fprintf(stderr, " --group-samples-tag TAG The tag to use with -G, by default FORMAT/QS and FORMAT/AD are checked automatically\n"); fprintf(stderr, " -g, --gvcf INT,[...] Group non-variant sites into gVCF blocks by minimum per-sample DP\n"); fprintf(stderr, " -i, --insert-missed Output also sites missed by mpileup but present in -T\n"); fprintf(stderr, " -M, --keep-masked-ref Keep sites with masked reference allele (REF=N)\n"); fprintf(stderr, " -V, --skip-variants TYPE Skip indels/snps\n"); fprintf(stderr, " -v, --variants-only Output variant sites only\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Consensus/variant calling options:\n"); fprintf(stderr, " -c, --consensus-caller The original calling method (conflicts with -m)\n"); fprintf(stderr, " -C, --constrain STR One of: alleles, trio (see manual)\n"); fprintf(stderr, " -m, --multiallelic-caller Alternative model for multiallelic and rare-variant calling (conflicts with -c)\n"); fprintf(stderr, " -n, --novel-rate FLOAT,[...] Likelihood of novel mutation for constrained trio calling, see man page for details [1e-8,1e-9,1e-9]\n"); fprintf(stderr, " -p, --pval-threshold FLOAT Variant if P(ref|D)aux.min_lrt); // fprintf(stderr, " -U INT number of permutations for association testing (effective with -1) [0]\n"); // fprintf(stderr, " -X FLOAT only perform permutations for P(chi^2)aux.min_perm_p); fprintf(stderr, "\n"); exit(-1); } int main_vcfcall(int argc, char *argv[]) { char *ploidy_fname = NULL, *ploidy = NULL; args_t args; memset(&args, 0, sizeof(args_t)); args.argc = argc; args.argv = argv; args.aux.prior_type = -1; args.aux.indel_frac = -1; args.aux.theta = 1.1e-3; args.aux.pref = 0.5; args.aux.min_perm_p = 0.01; args.aux.min_lrt = 1; args.flag = CF_ACGT_ONLY; args.output_fname = "-"; args.output_type = FT_VCF; args.n_threads = 0; args.record_cmd_line = 1; args.aux.trio_Pm_SNPs = 1 - 1e-8; args.aux.trio_Pm_ins = args.aux.trio_Pm_del = 1 - 1e-9; args.regions_overlap = 1; args.clevel = -1; int c; static struct option loptions[] = { {"help",no_argument,NULL,'h'}, {"format-fields",required_argument,NULL,'f'}, {"annotate",required_argument,NULL,'a'}, {"prior-freqs",required_argument,NULL,'F'}, {"gvcf",required_argument,NULL,'g'}, {"group-samples",required_argument,NULL,'G'}, {"group-samples-tag",required_argument,NULL,3}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,4}, {"samples",required_argument,NULL,'s'}, {"samples-file",required_argument,NULL,'S'}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"threads",required_argument,NULL,9}, {"keep-alts",no_argument,NULL,'A'}, {"keep-unseen-allele",no_argument,NULL,'*'}, {"insert-missed",no_argument,NULL,'i'}, {"skip-Ns",no_argument,NULL,'N'}, // now the new default {"keep-masked-refs",no_argument,NULL,'M'}, {"skip-variants",required_argument,NULL,'V'}, {"variants-only",no_argument,NULL,'v'}, {"consensus-caller",no_argument,NULL,'c'}, {"constrain",required_argument,NULL,'C'}, {"multiallelic-caller",no_argument,NULL,'m'}, {"pval-threshold",required_argument,NULL,'p'}, {"prior",required_argument,NULL,'P'}, {"novel-rate",required_argument,NULL,'n'}, {"ploidy",required_argument,NULL,1}, {"ploidy-file",required_argument,NULL,2}, {"chromosome-X",no_argument,NULL,'X'}, {"chromosome-Y",no_argument,NULL,'Y'}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp = NULL; while ((c = getopt_long(argc, argv, "h?o:O:r:R:s:S:t:T:A*NMV:vcmp:C:n:P:f:a:ig:XYF:G:W::", loptions, NULL)) >= 0) { switch (c) { case 2 : ploidy_fname = optarg; break; case 1 : ploidy = optarg; break; case 'X': ploidy = "X"; fprintf(stderr,"Warning: -X will be deprecated, please use --ploidy instead.\n"); break; case 'Y': ploidy = "Y"; fprintf(stderr,"Warning: -Y will be deprecated, please use --ploidy instead.\n"); break; case 'G': args.aux.sample_groups = optarg; break; case 3 : args.aux.sample_groups_tag = optarg; break; case 'f': fprintf(stderr,"Warning: -f, --format-fields will be deprecated, please use -a, --annotate instead.\n"); case 'a': if (optarg[0]=='?') { list_annotations(stderr); return 1; } args.aux.output_tags |= parse_output_tags(optarg); break; case 'M': args.flag &= ~CF_ACGT_ONLY; break; // keep sites where REF is N case 'N': args.flag |= CF_ACGT_ONLY; break; // omit sites where first base in REF is N (the new default) case 'A': args.aux.flag |= CALL_KEEPALT; break; case '*': args.aux.flag |= CALL_KEEP_UNSEEN; break; case 'c': args.flag |= CF_CCALL; break; // the original EM based calling method case 'i': args.flag |= CF_INS_MISSED; break; case 'v': args.aux.flag |= CALL_VARONLY; break; case 'F': args.aux.prior_AN = optarg; args.aux.prior_AC = strchr(optarg,','); if ( !args.aux.prior_AC ) error("Expected two tags with -F (e.g. AN,AC), got \"%s\"\n",optarg); *args.aux.prior_AC = 0; args.aux.prior_AC++; break; case 'g': args.gvcf = gvcf_init(optarg); if ( !args.gvcf ) error("Could not parse: --gvcf %s\n", optarg); break; case 'o': args.output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args.output_type = FT_BCF_GZ; break; case 'u': args.output_type = FT_BCF; break; case 'z': args.output_type = FT_VCF_GZ; break; case 'v': args.output_type = FT_VCF; break; default: { args.clevel = strtol(optarg,&tmp,10); if ( *tmp || args.clevel<0 || args.clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args.clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args.clevel<0 || args.clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'C': if ( !strcasecmp(optarg,"alleles") ) args.aux.flag |= CALL_CONSTR_ALLELES; else if ( !strcasecmp(optarg,"trio") ) args.aux.flag |= CALL_CONSTR_TRIO; else error("Unknown argument to -C: \"%s\"\n", optarg); break; case 'V': if ( !strcasecmp(optarg,"snps") ) args.flag |= CF_INDEL_ONLY; else if ( !strcasecmp(optarg,"indels") ) args.flag |= CF_NO_INDEL; else error("Unknown skip category \"%s\" (-S argument must be \"snps\" or \"indels\")\n", optarg); break; case 'm': args.flag |= CF_MCALL; break; // multiallelic calling method case 'p': args.aux.pref = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --pval-threshold %s\n", optarg); break; case 'P': args.aux.theta = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse, expected float argument: -P %s\n", optarg); break; case 'n': parse_novel_rate(&args,optarg); break; case 'r': args.regions = optarg; break; case 'R': args.regions = optarg; args.regions_is_file = 1; break; case 't': args.targets = optarg; break; case 'T': args.targets = optarg; args.targets_is_file = 1; break; case 's': args.samples_fname = optarg; break; case 'S': args.samples_fname = optarg; args.samples_is_file = 1; break; case 9 : args.n_threads = strtol(optarg, 0, 0); break; case 8 : args.record_cmd_line = 0; break; case 4 : args.regions_overlap = parse_overlap_option(optarg); if ( args.regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 'W': if (!(args.write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; default: usage(&args); } } // Sanity check options and initialize if ( ploidy_fname ) args.ploidy = ploidy_init(ploidy_fname, 2); else if ( ploidy ) args.ploidy = init_ploidy(ploidy); if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args.bcf_fname = "-"; // reading from stdin else usage(&args); } else args.bcf_fname = argv[optind++]; if ( !ploidy_fname && !ploidy ) { if ( !args.samples_is_file ) fprintf(stderr,"Note: none of --samples-file, --ploidy or --ploidy-file given, assuming all sites are diploid\n"); args.ploidy = ploidy_init_string("* * * 0 0\n* * * 1 1\n* * * 2 2\n",2); } if ( !args.ploidy ) error("Could not initialize ploidy\n"); if ( (args.flag & CF_CCALL ? 1 : 0) + (args.flag & CF_MCALL ? 1 : 0) + (args.flag & CF_QCALL ? 1 : 0) > 1 ) error("Only one of -c or -m options can be given\n"); if ( !(args.flag & CF_CCALL) && !(args.flag & CF_MCALL) && !(args.flag & CF_QCALL) ) error("Expected -c or -m option\n"); if ( (args.flag & CF_CCALL ? 1: 0) && args.gvcf ) error("gvcf -g option not functional with -c calling mode yet\n"); if ( args.aux.n_perm && args.aux.ngrp1_samples<=0 ) error("Expected -1 with -U\n"); // not sure about this, please fix if ( args.aux.flag & CALL_CONSTR_ALLELES ) { if ( !args.targets ) error("Expected -t or -T with \"-C alleles\"\n"); if ( !(args.flag & CF_MCALL) ) error("The \"-C alleles\" mode requires -m\n"); } if ( args.flag & CF_INS_MISSED && !(args.aux.flag&CALL_CONSTR_ALLELES) ) error("The -i option requires -C alleles\n"); if ( args.aux.flag&CALL_VARONLY && args.gvcf ) error("The two options cannot be combined: --variants-only and --gvcf\n"); if ( args.aux.sample_groups && !(args.flag & CF_MCALL) ) error("The -G feature is supported only with the -m calling mode\n"); init_data(&args); bcf1_t *bcf_rec; while ( (bcf_rec = next_line(&args)) ) { // Skip duplicate positions with all matching `-C alleles -T` used up if ( args.aux.flag&CALL_CONSTR_ALLELES && !args.aux.tgt_als ) continue; // Skip unwanted sites int i, is_indel = bcf_is_snp(bcf_rec) ? 0 : 1; if ( (args.flag & CF_INDEL_ONLY) && !is_indel ) continue; if ( (args.flag & CF_NO_INDEL) && is_indel ) continue; if ( (args.flag & CF_ACGT_ONLY) && (bcf_rec->d.allele[0][0]=='N' || bcf_rec->d.allele[0][0]=='n') ) continue; // REF[0] is 'N' // Which allele is symbolic? All SNPs should have it, but not indels args.aux.unseen = 0; for (i=1; in_allele; i++) { if ( bcf_rec->d.allele[i][0]=='X' ) { args.aux.unseen = i; break; } // old X if ( bcf_rec->d.allele[i][0]=='<' ) { if ( bcf_rec->d.allele[i][1]=='X' && bcf_rec->d.allele[i][2]=='>' ) { args.aux.unseen = i; break; } // old if ( bcf_rec->d.allele[i][1]=='*' && bcf_rec->d.allele[i][2]=='>' ) { args.aux.unseen = i; break; } // new <*> } } int is_ref = (bcf_rec->n_allele==1 || (bcf_rec->n_allele==2 && args.aux.unseen>0)) ? 1 : 0; if ( is_ref && args.aux.flag&CALL_VARONLY ) continue; bcf_unpack(bcf_rec, BCF_UN_ALL); if ( args.nsex ) set_ploidy(&args, bcf_rec); // Various output modes: QCall output (todo) if ( args.flag & CF_QCALL ) { qcall(&args.aux, bcf_rec); continue; } if ( args.flag & CF_INS_MISSED ) { tgt_flush(&args,bcf_rec); if ( !args.tgt_itr_prev ) args.tgt_itr_prev = regitr_init(args.tgt_idx); regitr_copy(args.tgt_itr_prev, args.tgt_itr); } // Calling modes which output VCFs int ret; if ( args.flag & CF_MCALL ) ret = mcall(&args.aux, bcf_rec); else ret = ccall(&args.aux, bcf_rec); if ( ret==-1 ) error("Something is wrong\n"); else if ( ret==-2 ) continue; // skip the site // Normal output if ( (args.aux.flag & CALL_VARONLY) && ret==0 && !args.gvcf ) continue; // not a variant if ( args.gvcf ) bcf_rec = gvcf_write(args.gvcf, args.out_fh, args.aux.hdr, bcf_rec, ret==1?1:0); if ( bcf_rec && bcf_write1(args.out_fh, args.aux.hdr, bcf_rec)!=0 ) error("[%s] Error: failed to write to %s\n", __func__,args.output_fname); } if ( args.gvcf ) gvcf_write(args.gvcf, args.out_fh, args.aux.hdr, NULL, 0); if ( args.flag & CF_INS_MISSED ) tgt_flush(&args,NULL); destroy_data(&args); return 0; } bcftools-1.21/vcfcnv.c000066400000000000000000001640321467060157400147210ustar00rootroot00000000000000/* The MIT License Copyright (c) 2014-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Known issues: - The --AF-file option behaves like --targets-file, sites not listed in the AFs are skipped. */ #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "HMM.h" #include "rbuf.h" #define DBG0 0 #define N_STATES 4 #define CN0 0 #define CN1 1 #define CN2 2 #define CN3 3 typedef struct { float mean, dev2, norm; } gauss_param_t; typedef struct { char *name; int idx; // VCF sample index float *lrr,*baf, baf_dev2, baf_dev2_dflt, lrr_dev2; float cell_frac, cell_frac_dflt; gauss_param_t gauss_param[18]; double pobs[N_STATES]; FILE *dat_fh, *cn_fh, *summary_fh; char *dat_fname, *cn_fname, *summary_fname; } sample_t; typedef struct _args_t { bcf_srs_t *files; bcf_hdr_t *hdr; int prev_rid, ntot, nused; sample_t query_sample, control_sample; int nstates; // number of states: N_STATES for one sample, N_STATES^2 for two samples double lrr_bias, baf_bias; // LRR/BAF weights double same_prob, ij_prob; // prior of both samples being the same and the transition probability P(i|j) double err_prob; // constant probability of erroneous measurement float *nonref_afs, nonref_af, nonref_af_dflt, fRR, fRA, fAA, *tmpf; unsigned long int nRR, nRA, nAA; int mtmpf; double *tprob, *tprob_arr; // array of transition matrices, precalculated up to ntprob_arr positions double *iprobs; // states' initial probabilities int ntprob_arr; hmm_t *hmm; double *eprob; // emission probs [nstates*nsites,msites] uint32_t *sites; // positions [nsites,msites] int nsites, msites; double baum_welch_th, optimize_frac; float plot_th; FILE *summary_fh; char **argv, *regions_list, *summary_fname, *output_dir; char *targets_list, *af_fname; int argc, verbose, lrr_smooth_win; } args_t; FILE *open_file(char **fname, const char *mode, const char *fmt, ...) HTS_FORMAT(HTS_PRINTF_FMT, 3, 4); static inline void hmm2cn_state(int nstates, int i, int *a, int *b) { *a = i / N_STATES; *b = i - (*a)*N_STATES; } static double *init_tprob_matrix(int ndim, double ij_prob, double same_prob) { int i,j; double *mat = (double*) malloc(sizeof(double)*ndim*ndim); assert( ndim==N_STATES || ndim==N_STATES*N_STATES); if ( ndim==N_STATES ) // one sample { double pii = 1 - ij_prob*(N_STATES-1); if ( pii < ij_prob ) error("Error: -x set a bit too high, P(x|x) < P(x|y): %e vs %e\n", pii,ij_prob); for (j=0; jdat_fh = open_file(&smpl->dat_fname,"w","%s/dat.%s.tab",dir,smpl->name); if ( !smpl->dat_fh ) error("Error opening file: %s/dat.%s.tab\n",dir,smpl->name); smpl->cn_fh = open_file(&smpl->cn_fname,"w","%s/cn.%s.tab",dir,smpl->name); if ( !smpl->cn_fh ) error("Error opening file: %s/cn.%s.tab\n",dir,smpl->name); smpl->summary_fh = open_file(&smpl->summary_fname,"w","%s/summary.%s.tab",dir,smpl->name); if ( !smpl->summary_fh ) error("Error opening file: %s/summary.%s.tab\n",dir,smpl->name); fprintf(smpl->dat_fh,"# [1]Chromosome\t[2]Position\t[3]BAF\t[4]LRR\n"); fprintf(smpl->cn_fh,"# [1]Chromosome\t[2]Position\t[3]CN\t[4]P(CN0)\t[5]P(CN1)\t[6]P(CN2)\t[7]P(CN3)\n"); fprintf(smpl->summary_fh,"# RG, Regions [2]Chromosome\t[3]Start\t[4]End\t[5]Copy Number state\t[6]Quality\t[7]nSites\t[8]nHETs\n"); } static void close_sample_files(sample_t *smpl) { if ( fclose(smpl->dat_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,smpl->dat_fname); if ( fclose(smpl->cn_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,smpl->cn_fname); if ( fclose(smpl->summary_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,smpl->summary_fname); } static double norm_cdf(double mean, double dev); static void init_data(args_t *args) { args->prev_rid = -1; args->hdr = args->files->readers[0].header; if ( !args->query_sample.name ) { if ( bcf_hdr_nsamples(args->hdr)>1 ) error("Multi-sample VCF, missing the -s option\n"); args->query_sample.name = strdup(args->hdr->samples[0]); } else if ( bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->query_sample.name)<0 ) error("The sample \"%s\" not found\n", args->query_sample.name); if ( !args->files->readers[0].file->is_bin ) { int ret; kstring_t tmp = {0,0,0}; if ( args->control_sample.name ) { ksprintf(&tmp, "%s,%s", args->query_sample.name,args->control_sample.name); ret = bcf_hdr_set_samples(args->hdr, tmp.s, 0); } else { ret = bcf_hdr_set_samples(args->hdr, args->query_sample.name, 0); tmp.s = args->query_sample.name; } if ( ret<0 ) error("Error parsing the list of samples: %s\n", tmp.s); else if ( ret>0 ) error("The sample not found in the VCF: %s\n", ret==1 ? args->query_sample.name : args->control_sample.name); if ( args->control_sample.name ) free(tmp.s); } args->query_sample.idx = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->query_sample.name); args->control_sample.idx = args->control_sample.name ? bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->control_sample.name) : -1; args->nstates = args->control_sample.name ? N_STATES*N_STATES : N_STATES; args->tprob = init_tprob_matrix(args->nstates, args->ij_prob, args->same_prob); args->iprobs = init_iprobs(args->nstates, args->same_prob); args->hmm = hmm_init(args->nstates, args->tprob, 10000); hmm_init_states(args->hmm, args->iprobs); args->summary_fh = stdout; init_sample_files(&args->query_sample, args->output_dir); if ( args->control_sample.name ) { init_sample_files(&args->control_sample, args->output_dir); args->summary_fh = open_file(&args->summary_fname,"w","%s/summary.tab",args->output_dir); } else args->summary_fh = NULL; // one sample only, no two-file summary int i; FILE *fh = args->summary_fh ? args->summary_fh : args->query_sample.summary_fh; fprintf(fh, "# This file was produced by: bcftools cnv(%s+htslib-%s)\n", bcftools_version(),hts_version()); fprintf(fh, "# The command line was:\tbcftools %s", args->argv[0]); for (i=1; iargc; i++) fprintf(fh, " %s",args->argv[i]); if ( args->control_sample.name ) fprintf(fh, "\n#\n" "# RG, Regions\t[2]Chromosome\t[3]Start\t[4]End\t[5]Copy number:%s\t[6]Copy number:%s\t[7]Quality" "\t[8]nSites in (5)\t[9]nHETs in (5)\t[10]nSites in (6)\t[11]nHETs in(6)\n", args->query_sample.name,args->control_sample.name ); else fprintf(fh, "\n#\n" "# RG, Regions\t[2]Chromosome\t[3]Start\t[4]End\t[5]Copy number:%s\t[6]Quality\t[7]nSites\t[8]nHETs\n", args->query_sample.name ); if ( args->optimize_frac ) { fprintf(args->query_sample.summary_fh, "# CF, cell fraction estimate\t[2]Chromosome\t[3]Start\t[4]End\t[5]Cell fraction\t[6]BAF deviation\n"); if ( args->control_sample.name ) { fprintf(args->control_sample.summary_fh, "# CF, cell fraction estimate\t[2]Chromosome\t[3]Start\t[4]End\t[5]Cell fraction\t[6]BAF deviation\n"); fprintf(args->summary_fh, "# CF, cell fraction estimate\t[2]Chromosome\t[3]Start\t[4]End\t" "[5]Cell fraction:%s\t[6]Cell fraction:%s\t[7]BAF deviation:%s\t[8]BAF deviation:%s\n", args->query_sample.name,args->control_sample.name, args->query_sample.name,args->control_sample.name ); } } } char *msprintf(const char *fmt, ...); static void py_plot_cnv(char *script, float th) { if ( th>100 ) return; // create no plots char *cmd = msprintf("python %s -p %f", script, th); int ret = system(cmd); if ( ret) fprintf(stderr, "The command returned non-zero status %d: %s\n", ret, cmd); free(cmd); } static void plot_sample(args_t *args, sample_t *smpl) { char *fname; FILE *fp = open_file(&fname,"w","%s/plot.%s.py",args->output_dir,smpl->name); fprintf(fp, "import matplotlib as mpl\n" "mpl.use('Agg')\n" "import matplotlib.pyplot as plt\n" "import csv\n" "import numpy as np\n" "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" "\n" "dat = {}\n" "with open('%s', 'r') as f:\n" " reader = csv.reader(f, 'tab')\n" " for row in reader:\n" " chr = row[0]\n" " if chr[0]=='#': continue\n" " if chr not in dat: dat[chr] = []\n" " dat[chr].append([int(row[1]), float(row[2]), float(row[3])])\n" "\n" "cnv = {}\n" "with open('%s', 'r') as f:\n" " reader = csv.reader(f, 'tab')\n" " for row in reader:\n" " chr = row[0]\n" " if chr[0]=='#': continue\n" " if chr not in cnv: cnv[chr] = []\n" " row[2] = int(row[2]) + 0.5\n" " row[1] = int(row[1])\n" " cnv[chr].append(row[1:])\n" "\n" "for chr in dat:\n" " fig,(ax1, ax2, ax3) = plt.subplots(3,1,figsize=(10,8),sharex=True)\n" " ax1.plot([x[0] for x in dat[chr]],[x[2] for x in dat[chr]], '.', ms=3)\n" " ax2.plot([x[0] for x in dat[chr]],[x[1] for x in dat[chr]], '.', ms=3)\n" " cn_dat = cnv[chr]\n" " xgrid = [float(x[0]) for x in cn_dat]\n" " ygrid = np.linspace(0,5,6)\n" " xgrid, ygrid = np.meshgrid(xgrid, ygrid)\n" " heat = np.zeros_like(xgrid)\n" " for x in range(len(heat[0])-1):\n" " heat[0][x] = cn_dat[x][2]\n" " heat[1][x] = cn_dat[x][3]\n" " heat[2][x] = cn_dat[x][4]\n" " heat[3][x] = cn_dat[x][5]\n" " mesh = ax3.pcolormesh(xgrid, ygrid, heat, cmap='bwr_r', shading='auto', alpha=0)\n" " mesh.set_clim(vmin=-1,vmax=1)\n" " ax3.plot([x[0] for x in cn_dat],[x[1] for x in cn_dat],'.-',ms=3,color='black')\n" " fig.suptitle('%s (chr '+chr+')')\n" " ax1.set_title('Log-R intensities Ratio',fontsize=10)\n" " ax2.set_title('B-Allele Frequency',fontsize=10)\n" " ax3.set_title('Copy Number Variation',fontsize=10)\n" " ax1.set_ylabel('LRR')\n" " ax2.set_ylabel('BAF')\n" " ax3.set_ylabel('CN')\n" " ax3.set_xlabel('Coordinate (chrom '+chr+')',fontsize=10)\n" " ax3.set_ylim(-0.1,4.1)\n" " ax3.set_yticks([0.5,1.5,2.5,3.5])\n" " ax3.set_yticklabels(['CN0','CN1','CN2','CN3'])\n" " plt.subplots_adjust(left=0.08,right=0.95,bottom=0.08,top=0.92)\n" " plt.savefig('%s/plot.%s.chr'+chr+'.png')\n" " plt.close()\n" "\n", smpl->dat_fname,smpl->cn_fname,smpl->name,args->output_dir,smpl->name ); fclose(fp); py_plot_cnv(fname, args->plot_th); free(fname); } static void create_plots(args_t *args) { close_sample_files(&args->query_sample); if ( args->control_sample.name ) close_sample_files(&args->control_sample); if ( args->summary_fh ) fclose(args->summary_fh); if ( !args->control_sample.name ) { plot_sample(args, &args->query_sample); return; } char *fname; FILE *fp = open_file(&fname,"w","%s/plot.%s.%s.py",args->output_dir,args->control_sample.name,args->query_sample.name); fprintf(fp, "import matplotlib as mpl\n" "mpl.use('Agg')\n" "import matplotlib.pyplot as plt\n" "import csv,argparse\n" "import numpy as np\n" "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" "\n" "control_sample = '%s'\n" "query_sample = '%s'\n" "\n" "parser = argparse.ArgumentParser()\n" "parser.add_argument('-p', '--plot-threshold', type=float)\n" "parser.add_argument('-c', '--chromosome')\n" "args = parser.parse_args()\n" "if args.plot_threshold==None: args.plot_threshold = 0\n" "\n" "def chroms_to_plot(th):\n" " dat = {}\n" " with open('%s/summary.tab', 'r') as f:\n" " reader = csv.reader(f, 'tab')\n" " for row in reader:\n" " if row[0]!='RG': continue\n" " chr = row[1]\n" " start = row[2]\n" " end = row[3]\n" " qual = float(row[6])\n" " if row[4]==row[5] and args.plot_threshold!=0: continue\n" " if chr not in dat: dat[chr] = 0.0\n" " if qual > dat[chr]: dat[chr] = qual\n" " out = {}\n" " for chr in dat:\n" " if (chr not in dat) or dat[chr]0: diff.append([b[i-1][0],b[i-1][1],a[i-1][1]])\n" " diff.append([b[i][0],b[i][1],a[i][1]])\n" " elif len(diff):\n" " diff.append([b[i][0],b[i][1],a[i][1]])\n" " out.append(diff)\n" " diff = []\n" " if len(diff): out.append(diff)\n" " return out\n" "\n" "for chr in sorted(plot_chroms.keys()):\n" " control_dat = []\n" " control_cnv = []\n" " query_dat = []\n" " query_cnv = []\n" " read_dat('%s',control_dat,chr)\n" " read_dat('%s',query_dat,chr)\n" " read_cnv('%s',control_cnv,chr)\n" " read_cnv('%s',query_cnv,chr)\n" "\n" " fig,(ax1,ax2,ax3,ax4,ax5,ax6) = plt.subplots(6,1,figsize=(10,8),sharex=True)\n" " ax1.plot([x[0] for x in control_dat],[x[2] for x in control_dat], '.', ms=3,color='red')\n" " ax2.plot([x[0] for x in control_dat],[x[1] for x in control_dat], '.', ms=3,color='red')\n" " cn_dat = control_cnv\n" " xgrid = [float(x[0]) for x in cn_dat]\n" " ygrid = np.linspace(0,5,6)\n" " xgrid, ygrid = np.meshgrid(xgrid, ygrid)\n" " heat = np.zeros_like(xgrid)\n" " for x in range(len(heat[0])-1):\n" " heat[0][x] = cn_dat[x][2]\n" " heat[1][x] = cn_dat[x][3]\n" " heat[2][x] = cn_dat[x][4]\n" " heat[3][x] = cn_dat[x][5]\n" " mesh = ax3.pcolormesh(xgrid, ygrid, heat, cmap='bwr', shading='auto', alpha=0)\n" " mesh.set_clim(vmin=-1,vmax=1)\n" " ax3.plot([x[0] for x in cn_dat],[x[1] for x in cn_dat],'-',ms=3,color='black',lw=1.7)\n" "\n" " ax6.plot([x[0] for x in query_dat],[x[2] for x in query_dat], '.', ms=3)\n" " ax5.plot([x[0] for x in query_dat],[x[1] for x in query_dat], '.', ms=3)\n" " cn_dat = query_cnv\n" " xgrid = [float(x[0]) for x in cn_dat]\n" " ygrid = np.linspace(0,5,6)\n" " xgrid, ygrid = np.meshgrid(xgrid, ygrid)\n" " heat = np.zeros_like(xgrid)\n" " for x in range(len(heat[0])-1):\n" " heat[0][x] = cn_dat[x][2]\n" " heat[1][x] = cn_dat[x][3]\n" " heat[2][x] = cn_dat[x][4]\n" " heat[3][x] = cn_dat[x][5]\n" " mesh = ax4.pcolormesh(xgrid, ygrid, heat, cmap='bwr_r')\n" " mesh.set_clim(vmin=-1,vmax=1)\n" " ax4.plot([x[0] for x in cn_dat],[x[1] for x in cn_dat],'-',ms=3,color='black',lw=1.7)\n" " ax3.annotate(control_sample, xy=(0.02,0.1), xycoords='axes fraction', color='red',fontsize=12, va='bottom',ha='left')\n" " ax4.annotate(query_sample, xy=(0.02,0.9), xycoords='axes fraction', color='blue',fontsize=12, va='top',ha='left')\n" "\n" " diffs = find_diffs(control_cnv,query_cnv)\n" " for diff in diffs:\n" " ax3.plot([x[0] for x in diff],[x[1] for x in diff],'-',ms=3,color='blue',lw=1.7)\n" " ax4.plot([x[0] for x in diff],[x[2] for x in diff],'-',ms=3,color='red',lw=1.7)\n" "\n" " fig.suptitle('chr '+chr+', '+control_sample+' vs '+query_sample)\n" " ax1.tick_params(axis='both', labelsize=8)\n" " ax2.tick_params(axis='both', labelsize=8)\n" " ax3.tick_params(axis='both', labelsize=8)\n" " ax4.tick_params(axis='both', labelsize=8)\n" " ax5.tick_params(axis='both', labelsize=8)\n" " ax6.tick_params(axis='both', labelsize=8)\n" " ax6.set_xlabel('Coordinate (chrom '+chr+')',fontsize=8)\n" " ax1.set_ylabel('LRR')\n" " ax2.set_ylabel('BAF')\n" " ax3.set_ylabel('CN')\n" " ax6.set_ylabel('LRR')\n" " ax5.set_ylabel('BAF')\n" " ax4.set_ylabel('CN')\n" " ax3.set_ylim(-0.1,4.1)\n" " ax3.set_yticks([0.5,1.5,2.5,3.5])\n" " ax3.set_yticklabels(['CN0','CN1','CN2','CN3'])\n" " ax4.set_ylim(-0.1,4.1)\n" " ax4.set_yticks([0.5,1.5,2.5,3.5])\n" " ax4.set_yticklabels(['CN0','CN1','CN2','CN3'])\n" " plt.subplots_adjust(left=0.08,right=0.95,bottom=0.08,top=0.92,hspace=0)\n" " plt.savefig('%s/plot.%s.%s.chr'+chr+'.png')\n" " plt.close()\n" "\n", args->control_sample.name,args->query_sample.name, args->output_dir, args->control_sample.dat_fname,args->query_sample.dat_fname, args->control_sample.cn_fname,args->query_sample.cn_fname, args->output_dir,args->control_sample.name,args->query_sample.name ); fclose(fp); py_plot_cnv(fname,args->plot_th); free(fname); } static void destroy_data(args_t *args) { bcf_sr_destroy(args->files); hmm_destroy(args->hmm); free(args->tmpf); free(args->sites); free(args->eprob); free(args->tprob); free(args->iprobs); free(args->summary_fname); free(args->nonref_afs); free(args->query_sample.baf); free(args->query_sample.lrr); free(args->control_sample.baf); free(args->control_sample.lrr); free(args->query_sample.name); free(args->query_sample.dat_fname); free(args->query_sample.cn_fname); free(args->query_sample.summary_fname); free(args->control_sample.dat_fname); free(args->control_sample.cn_fname); free(args->control_sample.summary_fname); } static inline char copy_number_state(args_t *args, int istate, int ismpl) { char code[] = "01234"; if ( !args->control_sample.name ) return code[istate]; int idx = ismpl ? istate - (istate/N_STATES)*N_STATES : istate/N_STATES; return code[idx]; } static double avg_ii_prob(int n, double *mat) { int i; double avg = 0; for (i=0; igauss_param[0])) #define GAUSS_CN1_PK_A(smpl) (&((smpl)->gauss_param[1])) #define GAUSS_CN2_PK_RR(smpl) (&((smpl)->gauss_param[2])) #define GAUSS_CN2_PK_RA(smpl) (&((smpl)->gauss_param[3])) #define GAUSS_CN2_PK_AA(smpl) (&((smpl)->gauss_param[4])) #define GAUSS_CN3_PK_RRR(smpl) (&((smpl)->gauss_param[5])) #define GAUSS_CN3_PK_RRA(smpl) (&((smpl)->gauss_param[6])) #define GAUSS_CN3_PK_RAA(smpl) (&((smpl)->gauss_param[7])) #define GAUSS_CN3_PK_AAA(smpl) (&((smpl)->gauss_param[8])) static inline double norm_prob(double baf, gauss_param_t *param) { return exp(-(baf-param->mean)*(baf-param->mean)*0.5/param->dev2) / param->norm / sqrt(2*M_PI*param->dev2); } static int set_observed_prob(args_t *args, sample_t *smpl, int isite) { float baf = smpl->baf[isite]; float lrr = args->lrr_bias>0 ? smpl->lrr[isite] : 0; float fRR = args->fRR; float fRA = args->fRA; float fAA = args->fAA; if ( baf<0 ) { // no call: either some technical issue or the call could not be made because it is CN0 int i; smpl->pobs[CN0] = 0.5; for (i=1; ipobs[i] = (1.0-smpl->pobs[CN0])/(N_STATES-1); return 0; } double cn1_baf = norm_prob(baf,GAUSS_CN1_PK_R(smpl)) * (fRR + fRA*0.5) + norm_prob(baf,GAUSS_CN1_PK_A(smpl)) * (fAA + fRA*0.5) ; double cn2_baf = norm_prob(baf,GAUSS_CN2_PK_RR(smpl)) * fRR + norm_prob(baf,GAUSS_CN2_PK_RA(smpl)) * fRA + norm_prob(baf,GAUSS_CN2_PK_AA(smpl)) * fAA; double cn3_baf = norm_prob(baf,GAUSS_CN3_PK_RRR(smpl)) * fRR + norm_prob(baf,GAUSS_CN3_PK_RRA(smpl)) * fRA*0.5 + norm_prob(baf,GAUSS_CN3_PK_RAA(smpl)) * fRA*0.5 + norm_prob(baf,GAUSS_CN3_PK_AAA(smpl)) * fAA; double norm = cn1_baf + cn2_baf + cn3_baf; cn1_baf /= norm; cn2_baf /= norm; cn3_baf /= norm; #if DBG0 if ( args->verbose ) fprintf(stderr,"%f\t%f %f %f\n", baf,cn1_baf,cn2_baf,cn3_baf); #endif double cn1_lrr = exp(-(lrr + 0.45)*(lrr + 0.45)/smpl->lrr_dev2); double cn2_lrr = exp(-(lrr - 0.00)*(lrr - 0.00)/smpl->lrr_dev2); double cn3_lrr = exp(-(lrr - 0.30)*(lrr - 0.30)/smpl->lrr_dev2); smpl->pobs[CN0] = 0; smpl->pobs[CN1] = args->err_prob + (1 - args->baf_bias + args->baf_bias*cn1_baf)*(1 - args->lrr_bias + args->lrr_bias*cn1_lrr); smpl->pobs[CN2] = args->err_prob + (1 - args->baf_bias + args->baf_bias*cn2_baf)*(1 - args->lrr_bias + args->lrr_bias*cn2_lrr); smpl->pobs[CN3] = args->err_prob + (1 - args->baf_bias + args->baf_bias*cn3_baf)*(1 - args->lrr_bias + args->lrr_bias*cn3_lrr); return 0; } static void set_emission_prob(args_t *args, int isite) { double *eprob = &args->eprob[args->nstates*isite]; int i; for (i=0; iquery_sample.pobs[i]; } static void set_emission_prob2(args_t *args, int isite) { double *eprob = &args->eprob[args->nstates*isite]; int i, j; for (i=0; iquery_sample.pobs[i]*args->control_sample.pobs[j]; } } } static void set_gauss_params(args_t *args, sample_t *smpl); static double norm_cdf(double mean, double dev) { double bot = 0, top = 1; top = 1 - 0.5*erfc((top-mean)/(dev*sqrt(2))); bot = 1 - 0.5*erfc((bot-mean)/(dev*sqrt(2))); return top-bot; } static void set_emission_probs(args_t *args) { if ( !args->af_fname ) { args->fRR = 0.76; args->fRA = 0.14; args->fAA = 0.098; } set_gauss_params(args, &args->query_sample); if ( args->control_sample.name ) set_gauss_params(args, &args->control_sample); #if DBG0 args->verbose = 1; args->query_sample.baf[0] = 0; set_observed_prob(args,&args->query_sample,0); args->query_sample.baf[0] = 1/3.; set_observed_prob(args,&args->query_sample,0); args->query_sample.baf[0] = 1/2.; set_observed_prob(args,&args->query_sample,0); args->query_sample.baf[0] = 2/3.; set_observed_prob(args,&args->query_sample,0); args->query_sample.baf[0] = 1; set_observed_prob(args,&args->query_sample,0); args->verbose = 0; #endif int i; for (i=0; insites; i++) { if ( args->af_fname ) { args->fRR = (1-args->nonref_afs[i])*(1-args->nonref_afs[i]); args->fRA = 2*args->nonref_afs[i]*(1-args->nonref_afs[i]); args->fAA = args->nonref_afs[i]*args->nonref_afs[i]; } set_observed_prob(args,&args->query_sample,i); if ( args->control_sample.name ) { set_observed_prob(args,&args->control_sample,i); set_emission_prob2(args,i); } else set_emission_prob(args,i); } } static void smooth_data(float *dat, int ndat, int win) { if ( win<=1 ) return; int i,j, k1 = win/2, k2 = win-k1; rbuf_t rbuf; rbuf_init(&rbuf,win); float sum = 0, *buf = (float*)malloc(sizeof(float)*win); for (i=0; i=k1 ) { j = rbuf_shift(&rbuf); sum -= buf[j]; } if ( i+k2gauss_param[i].dev2 = smpl->baf_dev2; double dev = sqrt(smpl->baf_dev2); GAUSS_CN1_PK_R(smpl)->mean = 0; GAUSS_CN1_PK_A(smpl)->mean = 1; GAUSS_CN1_PK_R(smpl)->norm = norm_cdf(GAUSS_CN1_PK_R(smpl)->mean,dev); GAUSS_CN1_PK_A(smpl)->norm = norm_cdf(GAUSS_CN1_PK_A(smpl)->mean,dev); GAUSS_CN2_PK_RR(smpl)->mean = 0; GAUSS_CN2_PK_RA(smpl)->mean = 0.5; GAUSS_CN2_PK_AA(smpl)->mean = 1; GAUSS_CN2_PK_RR(smpl)->norm = norm_cdf(GAUSS_CN2_PK_RR(smpl)->mean,dev); GAUSS_CN2_PK_RA(smpl)->norm = norm_cdf(GAUSS_CN2_PK_RA(smpl)->mean,dev); GAUSS_CN2_PK_AA(smpl)->norm = norm_cdf(GAUSS_CN2_PK_AA(smpl)->mean,dev); GAUSS_CN3_PK_RRR(smpl)->mean = 0; GAUSS_CN3_PK_RRA(smpl)->mean = 1.0/(2+smpl->cell_frac); GAUSS_CN3_PK_RAA(smpl)->mean = (1.0+smpl->cell_frac)/(2+smpl->cell_frac); GAUSS_CN3_PK_AAA(smpl)->mean = 1; GAUSS_CN3_PK_RRR(smpl)->norm = norm_cdf(GAUSS_CN3_PK_RRR(smpl)->mean,dev); GAUSS_CN3_PK_RRA(smpl)->norm = norm_cdf(GAUSS_CN3_PK_RRA(smpl)->mean,dev); GAUSS_CN3_PK_RAA(smpl)->norm = norm_cdf(GAUSS_CN3_PK_RAA(smpl)->mean,dev); GAUSS_CN3_PK_AAA(smpl)->norm = norm_cdf(GAUSS_CN3_PK_AAA(smpl)->mean,dev); } static int update_sample_args(args_t *args, sample_t *smpl, int ismpl) { hmm_t *hmm = args->hmm; double *fwd = hmm_get_fwd_bwd_prob(hmm); int nstates = hmm_get_nstates(hmm); // estimate the BAF mean and deviation for CN3 double mean_cn3 = 0, norm_cn3 = 0; double baf_dev2 = 0, baf_AA_dev2 = 0, norm_baf_AA_dev2 = 0; // experimental: smooth CN3 probs to bias toward bigger events, this lowers // the FP rate when the data is noisy hts_expand(float,args->nsites,args->mtmpf,args->tmpf); int i, j, k = 0; for (i=0; insites; i++) { float baf = smpl->baf[i]; if ( baf>4/5.) continue; // skip AA genotypes if ( baf>0.5 ) baf = 1 - baf; // the bands should be symmetric if ( baf<1/5.) continue; // skip RR genotypes double prob_cn3 = 0, *probs = fwd + i*nstates; if ( !args->control_sample.name ) { prob_cn3 = probs[CN3]; } else if ( ismpl==0 ) { // query sample: CN3 probability must be recovered from all states of the control sample for (j=0; jtmpf[k++] = prob_cn3; } smooth_data(args->tmpf, k, 50); k = 0; for (i=0; insites; i++) { float baf = smpl->baf[i]; if ( baf>4/5.) { baf_AA_dev2 += (1.0-baf)*(1.0-baf); norm_baf_AA_dev2++; continue; } // skip AA genotypes if ( baf>0.5 ) baf = 1 - baf; // the bands should be symmetric if ( baf<1/5.) continue; // skip RR genotypes double prob_cn3 = args->tmpf[k++]; mean_cn3 += prob_cn3 * baf; norm_cn3 += prob_cn3; } if ( !norm_cn3 ) { smpl->cell_frac = 1.0; return 1; } mean_cn3 /= norm_cn3; k = 0; for (i=0; insites; i++) { float baf = smpl->baf[i]; if ( baf>0.5 ) baf = 1 - baf; // the bands should be symmetric if ( baf<1/5.) continue; // skip RR,AA genotypes double prob_cn3 = args->tmpf[k++]; baf_dev2 += prob_cn3 * (baf - mean_cn3)*(baf - mean_cn3); } /* A noisy CN2 band is hard to distinguish from two CN3 bands which are close to each other. Set a threshold on the minimum separation based on the BAF deviation at p=0.95 */ baf_dev2 /= norm_cn3; baf_AA_dev2 /= norm_baf_AA_dev2; if ( baf_dev2 < baf_AA_dev2 ) baf_dev2 = baf_AA_dev2; double max_mean_cn3 = 0.5 - sqrt(baf_dev2)*1.644854; // R: qnorm(0.95)=1.644854 //fprintf(stderr,"dev=%f AA_dev=%f max_mean_cn3=%f mean_cn3=%f\n", baf_dev2,baf_AA_dev2,max_mean_cn3,mean_cn3); assert( max_mean_cn3>0 ); double new_frac = 1./mean_cn3 - 2; if ( mean_cn3 > max_mean_cn3 || new_frac < args->optimize_frac ) { // out of bounds, beyond our detection limits. Give up and say it converged smpl->cell_frac = 1.0; return 1; } if ( new_frac>1 ) new_frac = 1; int converged = fabs(new_frac - smpl->cell_frac) < 1e-1 ? 1 : 0; // Update dev2, but stay within safe limits if ( baf_dev2 > 3*smpl->baf_dev2_dflt ) baf_dev2 = 3*smpl->baf_dev2_dflt; else if ( baf_dev2 < 0.5*smpl->baf_dev2_dflt ) baf_dev2 = 0.5*smpl->baf_dev2_dflt; smpl->cell_frac = new_frac; smpl->baf_dev2 = baf_dev2; return converged; } // Update parameters which depend on the estimated fraction of aberrant cells // in CN3. Returns 0 if the current estimate did not need to be updated or 1 // if there was a change. static int update_args(args_t *args) { int converged = update_sample_args(args, &args->query_sample, 0); if ( args->control_sample.name ) { converged += update_sample_args(args, &args->control_sample, 1); return converged==2 ? 0 : 1; } return converged ? 0 : 1; } // for an approximate estimate of the number of het genotypes in a region #define BAF_LIKELY_HET(val) (val)>0.25 && (val)<0.75 static void cnv_flush_viterbi(args_t *args) { if ( !args->nsites ) return; // Set HMM transition matrix for the new chromsome again. This is for case // Baum-Welch was used, which is experimental, largerly unsupported and not // done by default. hmm_t *hmm = args->hmm; hmm_set_tprob(args->hmm, args->tprob, 10000); // Smooth LRR values to reduce noise if ( args->lrr_bias > 0 ) { smooth_data(args->query_sample.lrr,args->nsites, args->lrr_smooth_win); if ( args->control_sample.name ) smooth_data(args->control_sample.lrr,args->nsites, args->lrr_smooth_win); } // Set the BAF peak likelihoods, such as P(RRR|CN3), taking account the // estimated fraction of aberrant cells in the mixture. With the new chromosome, // reset the fraction to the default value. args->query_sample.cell_frac = args->query_sample.cell_frac_dflt; args->control_sample.cell_frac = args->control_sample.cell_frac_dflt; args->query_sample.baf_dev2 = args->query_sample.baf_dev2_dflt; args->control_sample.baf_dev2 = args->control_sample.baf_dev2_dflt; set_gauss_params(args, &args->query_sample); if ( args->control_sample.name ) set_gauss_params(args, &args->control_sample); if ( args->optimize_frac ) { int niter = 0; fprintf(stderr,"Attempting to estimate the fraction of aberrant cells (chr %s):\n", bcf_hdr_id2name(args->hdr,args->prev_rid)); do { fprintf(stderr,"\t.. %f %f", args->query_sample.cell_frac,args->query_sample.baf_dev2); if ( args->control_sample.name ) fprintf(stderr,"\t.. %f %f", args->control_sample.cell_frac,args->control_sample.baf_dev2); fprintf(stderr,"\n"); set_emission_probs(args); hmm_run_fwd_bwd(hmm, args->nsites, args->eprob, args->sites); } while ( update_args(args) && ++niter<20 ); if ( niter>=20 ) { // no convergence args->query_sample.cell_frac = args->query_sample.cell_frac_dflt; args->control_sample.cell_frac = args->control_sample.cell_frac_dflt; args->query_sample.baf_dev2 = args->query_sample.baf_dev2_dflt; args->control_sample.baf_dev2 = args->control_sample.baf_dev2_dflt; set_gauss_params(args, &args->query_sample); if ( args->control_sample.name ) set_gauss_params(args, &args->control_sample); } fprintf(stderr,"\t.. %f %f", args->query_sample.cell_frac,args->query_sample.baf_dev2); if ( args->control_sample.name ) fprintf(stderr,"\t.. %f %f", args->control_sample.cell_frac,args->control_sample.baf_dev2); fprintf(stderr,"\n"); fprintf(args->query_sample.summary_fh,"CF\t%s\t%d\t%d\t%.2f\t%f\n", bcf_hdr_id2name(args->hdr,args->prev_rid),args->sites[0]+1,args->sites[args->nsites-1]+1, args->query_sample.cell_frac,sqrt(args->query_sample.baf_dev2)); if ( args->control_sample.name ) { fprintf(args->control_sample.summary_fh,"CF\t%s\t%d\t%d\t%.2f\t%f\n", bcf_hdr_id2name(args->hdr,args->prev_rid),args->sites[0]+1,args->sites[args->nsites-1]+1, args->control_sample.cell_frac,sqrt(args->control_sample.baf_dev2)); fprintf(args->summary_fh,"CF\t%s\t%d\t%d\t%.2f\t%.2f\t%f\t%f\n", bcf_hdr_id2name(args->hdr,args->prev_rid),args->sites[0]+1,args->sites[args->nsites-1]+1, args->query_sample.cell_frac, args->control_sample.cell_frac, sqrt(args->query_sample.baf_dev2), sqrt(args->control_sample.baf_dev2)); } } set_emission_probs(args); while ( args->baum_welch_th!=0 ) { int nstates = hmm_get_nstates(hmm); double ori_ii = avg_ii_prob(nstates,hmm_get_tprob(hmm)); hmm_run_baum_welch(hmm, args->nsites, args->eprob, args->sites); double new_ii = avg_ii_prob(nstates,hmm_get_tprob(hmm)); fprintf(stderr,"%e\t%e\t%e\n", ori_ii,new_ii,new_ii-ori_ii); double *tprob = init_tprob_matrix(nstates, 1-new_ii, args->same_prob); hmm_set_tprob(args->hmm, tprob, 10000); double *tprob_arr = hmm_get_tprob(hmm); free(tprob); if ( fabs(new_ii - ori_ii) < args->baum_welch_th ) { int i,j; for (i=0; insites, args->eprob, args->sites); hmm_run_fwd_bwd(hmm, args->nsites, args->eprob, args->sites); // Output the results uint8_t *vpath = hmm_get_viterbi_path(hmm); double qual = 0, *fwd = hmm_get_fwd_bwd_prob(hmm); int i,j, isite, start_cn = vpath[0], start_pos = args->sites[0], istart_pos = 0; int ctrl_ntot = 0, smpl_ntot = 0, ctrl_nhet = 0, smpl_nhet = 0; for (isite=0; isitensites; isite++) { int state = vpath[args->nstates*isite]; double *pval = fwd + isite*args->nstates; qual += pval[start_cn]; // output CN and fwd-bwd likelihood for each site if ( args->query_sample.cn_fh ) { fprintf(args->query_sample.cn_fh, "%s\t%d\t%c", bcf_hdr_id2name(args->hdr,args->prev_rid), args->sites[isite]+1, copy_number_state(args,state,0)); if ( !args->control_sample.cn_fh ) for (i=0; instates; i++) fprintf(args->query_sample.cn_fh, "\t%f", pval[i]); else for (i=0; iquery_sample.cn_fh, "\t%f", sum); } fprintf(args->query_sample.cn_fh, "\n"); if ( args->query_sample.baf[isite]>=0 ) // if non-missing { if ( BAF_LIKELY_HET(args->query_sample.baf[isite]) ) smpl_nhet++; smpl_ntot++; } } if ( args->control_sample.cn_fh ) { fprintf(args->control_sample.cn_fh, "%s\t%d\t%c", bcf_hdr_id2name(args->hdr,args->prev_rid), args->sites[isite]+1, copy_number_state(args,state,1)); for (i=0; icontrol_sample.cn_fh, "\t%f", sum); } fprintf(args->control_sample.cn_fh, "\n"); if ( args->control_sample.baf[isite]>=0 ) // if non-missing { if ( BAF_LIKELY_HET(args->control_sample.baf[isite]) ) ctrl_nhet++; ctrl_ntot++; } } if ( start_cn != state ) { char start_cn_query = copy_number_state(args,start_cn,0); qual = phred_score(1 - qual/(isite - istart_pos)); fprintf(args->query_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite],start_cn_query,qual,smpl_ntot,smpl_nhet); if ( args->control_sample.name ) { // regions 0-based, half-open char start_cn_ctrl = copy_number_state(args,start_cn,1); fprintf(args->control_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite],start_cn_ctrl,qual,ctrl_ntot,ctrl_nhet); fprintf(args->summary_fh,"RG\t%s\t%d\t%d\t%c\t%c\t%.1f\t%d\t%d\t%d\t%d\n", bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite],start_cn_query,start_cn_ctrl,qual,smpl_ntot,smpl_nhet,ctrl_ntot,ctrl_nhet); } istart_pos = isite; start_pos = args->sites[isite]; start_cn = state; qual = 0; smpl_ntot = smpl_nhet = ctrl_ntot = ctrl_nhet = 0; } } qual = phred_score(1 - qual/(isite - istart_pos)); char start_cn_query = copy_number_state(args,start_cn,0); fprintf(args->query_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite-1]+1,start_cn_query,qual,smpl_ntot,smpl_nhet); if ( args->control_sample.name ) { char start_cn_ctrl = copy_number_state(args,start_cn,1); fprintf(args->control_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite-1]+1,start_cn_ctrl,qual,ctrl_ntot,ctrl_nhet); fprintf(args->summary_fh,"RG\t%s\t%d\t%d\t%c\t%c\t%.1f\t%d\t%d\t%d\t%d\n", bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite-1]+1,start_cn_query,start_cn_ctrl,qual,smpl_ntot,smpl_nhet,ctrl_ntot,ctrl_nhet); } } static int parse_lrr_baf(sample_t *smpl, bcf_fmt_t *baf_fmt, bcf_fmt_t *lrr_fmt, float *baf, float *lrr) { *baf = ((float*)(baf_fmt->p + baf_fmt->size*smpl->idx))[0]; if ( bcf_float_is_missing(*baf) || isnan(*baf) ) *baf = -0.1; // arbitrary negative value == missing value if ( lrr_fmt ) { *lrr = ((float*)(lrr_fmt->p + lrr_fmt->size*smpl->idx))[0]; if ( bcf_float_is_missing(*lrr) || isnan(*lrr) ) { *lrr = 0; *baf = -0.1; } } else *lrr = 0; return *baf<0 ? 0 : 1; } static void cnv_next_line(args_t *args, bcf1_t *line) { if ( !line ) { // Done, flush viterbi cnv_flush_viterbi(args); return; } if ( line->rid!=args->prev_rid ) { // New chromosome cnv_flush_viterbi(args); args->prev_rid = line->rid; args->nsites = 0; args->nRR = args->nAA = args->nRA = 0; } // Process line args->ntot++; bcf_fmt_t *baf_fmt, *lrr_fmt = NULL; if ( !(baf_fmt = bcf_get_fmt(args->hdr, line, "BAF")) ) return; if ( args->lrr_bias>0 && !(lrr_fmt = bcf_get_fmt(args->hdr, line, "LRR")) ) return; float baf1,lrr1,baf2,lrr2; int ret = 0; ret += parse_lrr_baf(&args->query_sample, baf_fmt,lrr_fmt,&baf1,&lrr1); ret += parse_lrr_baf(&args->control_sample,baf_fmt,lrr_fmt,&baf2,&lrr2); if ( !ret ) return; // Realloc buffers needed to store observed data and used by viterbi and fwd-bwd args->nsites++; int m = args->msites; hts_expand(uint32_t,args->nsites,args->msites,args->sites); if ( args->msites!=m ) { args->eprob = (double*) realloc(args->eprob,sizeof(double)*args->msites*args->nstates); if ( args->control_sample.name ) { args->control_sample.lrr = (float*) realloc(args->control_sample.lrr,sizeof(float)*args->msites); args->control_sample.baf = (float*) realloc(args->control_sample.baf,sizeof(float)*args->msites); } args->query_sample.lrr = (float*) realloc(args->query_sample.lrr,sizeof(float)*args->msites); args->query_sample.baf = (float*) realloc(args->query_sample.baf,sizeof(float)*args->msites); if ( args->af_fname ) args->nonref_afs = (float*) realloc(args->nonref_afs,sizeof(float)*args->msites); } args->sites[args->nsites-1] = line->pos; args->query_sample.lrr[args->nsites-1] = lrr1; args->query_sample.baf[args->nsites-1] = baf1; if ( args->af_fname ) { double alt_freq; args->nonref_afs[args->nsites-1] = read_AF(args->files->targets,line,&alt_freq)<0 ? args->nonref_af_dflt : alt_freq; } if ( args->control_sample.name ) { args->control_sample.lrr[args->nsites-1] = lrr2; args->control_sample.baf[args->nsites-1] = baf2; if ( baf2>=0 ) // skip missing values fprintf(args->control_sample.dat_fh,"%s\t%"PRId64"\t%.3f\t%.3f\n",bcf_hdr_id2name(args->hdr,args->prev_rid), (int64_t) line->pos+1,baf2,lrr2); } if ( baf1>=0 ) // skip missing values fprintf(args->query_sample.dat_fh,"%s\t%"PRId64"\t%.3f\t%.3f\n",bcf_hdr_id2name(args->hdr,args->prev_rid), (int64_t) line->pos+1,baf1,lrr1); if ( baf1>=0 ) { if ( baf1<1/5. ) args->nRR++; else if ( baf1>4/5. ) args->nAA++; else args->nRA++; } args->nused++; } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Copy number variation caller, requires Illumina's B-allele frequency (BAF) and Log R\n"); fprintf(stderr, " Ratio intensity (LRR). The HMM considers the following copy number states: CN 2\n"); fprintf(stderr, " (normal), 1 (single-copy loss), 0 (complete loss), 3 (single-copy gain)\n"); fprintf(stderr, "Usage: bcftools cnv [OPTIONS] FILE.vcf\n"); fprintf(stderr, "General Options:\n"); fprintf(stderr, " -c, --control-sample STRING Optional control sample name to highlight differences\n"); fprintf(stderr, " -f, --AF-file FILE Read allele frequencies from file (CHR\\tPOS\\tREF,ALT\\tAF)\n"); fprintf(stderr, " -o, --output-dir PATH \n"); fprintf(stderr, " -p, --plot-threshold FLOAT Plot aberrant chromosomes with quality at least FLOAT\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --query-sample STRING Query samply name\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, "HMM Options:\n"); fprintf(stderr, " -a, --aberrant FLOAT[,FLOAT] Fraction of aberrant cells in query and control [1.0,1.0]\n"); fprintf(stderr, " -b, --BAF-weight FLOAT Relative contribution from BAF [1]\n"); fprintf(stderr, " -d, --BAF-dev FLOAT[,FLOAT] Expected BAF deviation in query and control [0.04,0.04]\n"); // experimental fprintf(stderr, " -e, --err-prob FLOAT Uniform error probability [1e-4]\n"); fprintf(stderr, " -k, --LRR-dev FLOAT[,FLOAT] Expected LRR deviation [0.2,0.2]\n"); // experimental fprintf(stderr, " -l, --LRR-weight FLOAT Relative contribution from LRR [0.2]\n"); fprintf(stderr, " -L, --LRR-smooth-win INT Window of LRR moving average smoothing [10]\n"); fprintf(stderr, " -O, --optimize FLOAT Estimate fraction of aberrant cells down to FLOAT [1.0]\n"); fprintf(stderr, " -P, --same-prob FLOA> Prior probability of -s/-c being the same [0.5]\n"); fprintf(stderr, " -x, --xy-prob FLOAT P(x|y) transition probability [1e-9]\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfcnv(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->files = bcf_sr_init(); args->plot_th = 1e9; // by default plot none args->nonref_af_dflt = 0.1; args->lrr_smooth_win = 10; args->query_sample.cell_frac_dflt = 1; args->control_sample.cell_frac_dflt = 1; // How much FORMAT/LRR and FORMAT/BAF matter args->lrr_bias = 0.2; args->baf_bias = 1.0; args->err_prob = 1e-4; // Transition probability to a different state and the prior of both samples being the same args->ij_prob = 1e-9; args->same_prob = 0.5; // Squared std dev of BAF and LRR values (gaussian noise), estimated from real data (hets, one sample, one chr) args->query_sample.baf_dev2_dflt = args->control_sample.baf_dev2_dflt = 0.04*0.04; // illumina: 0.03 args->query_sample.lrr_dev2 = args->control_sample.lrr_dev2 = 0.2*0.2; //0.20*0.20; // illumina: 0.18 int regions_is_file = 0, targets_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; static struct option loptions[] = { {"BAF-dev",1,0,'d'}, {"LRR-dev",1,0,'k'}, {"LRR-smooth-win",1,0,'L'}, {"AF-file",1,0,'f'}, {"baum-welch",1,0,'W'}, // hidden {"optimize",1,0,'O'}, {"aberrant",1,0,'a'}, {"err-prob",1,0,'e'}, {"BAF-weight",1,0,'b'}, {"LRR-weight",1,0,'l'}, {"same-prob",1,0,'P'}, {"xy-prob",1,0,'x'}, {"query-sample",1,0,'s'}, {"control-sample",1,0,'c'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,4}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,3}, {"plot-threshold",1,0,'p'}, {"output-dir",1,0,'o'}, {0,0,0,0} }; char *tmp = NULL; while ((c = getopt_long(argc, argv, "h?r:R:t:T:s:o:p:l:T:c:b:P:x:e:O:W::f:a:L:d:k:",loptions,NULL)) >= 0) { switch (c) { case 'L': args->lrr_smooth_win = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse: --LRR-smooth-win %s\n", optarg); break; case 'f': args->af_fname = optarg; break; case 'O': args->optimize_frac = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -O %s\n", optarg); break; case 'd': args->query_sample.baf_dev2_dflt = strtod(optarg,&tmp); if ( *tmp ) { if ( *tmp!=',') error("Could not parse: -d %s\n", optarg); args->control_sample.baf_dev2_dflt = strtod(tmp+1,&tmp); if ( *tmp ) error("Could not parse: -d %s\n", optarg); } else args->control_sample.baf_dev2_dflt = args->query_sample.baf_dev2_dflt; args->query_sample.baf_dev2_dflt *= args->query_sample.baf_dev2_dflt; args->control_sample.baf_dev2_dflt *= args->control_sample.baf_dev2_dflt; break; case 'k': args->query_sample.lrr_dev2 = strtod(optarg,&tmp); if ( *tmp ) { if ( *tmp!=',') error("Could not parse: -k %s\n", optarg); args->control_sample.lrr_dev2 = strtod(tmp+1,&tmp); if ( *tmp ) error("Could not parse: -d %s\n", optarg); } else args->control_sample.lrr_dev2 = args->query_sample.lrr_dev2; args->query_sample.lrr_dev2 *= args->query_sample.lrr_dev2; args->control_sample.lrr_dev2 *= args->control_sample.lrr_dev2; break; case 'a': args->query_sample.cell_frac_dflt = strtod(optarg,&tmp); if ( *tmp ) { if ( *tmp!=',') error("Could not parse: -a %s\n", optarg); args->control_sample.cell_frac_dflt = strtod(tmp+1,&tmp); if ( *tmp ) error("Could not parse: -a %s\n", optarg); } break; case 'W': args->baum_welch_th = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -W %s\n", optarg); break; case 'e': args->err_prob = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -e %s\n", optarg); break; case 'b': args->baf_bias = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -b %s\n", optarg); break; case 'x': args->ij_prob = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -x %s\n", optarg); break; case 'P': args->same_prob = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -P %s\n", optarg); break; case 'l': args->lrr_bias = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -l %s\n", optarg); break; case 'p': args->plot_th = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -p %s\n", optarg); break; case 'o': args->output_dir = optarg; break; case 's': args->query_sample.name = strdup(optarg); break; case 'c': args->control_sample.name = optarg; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 3 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'h': case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; } else fname = argv[optind]; if ( !fname ) usage(args); if ( !args->output_dir ) error("Expected -o option\n"); if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( args->af_fname ) { if ( bcf_sr_set_targets(args->files, args->af_fname, 1, 3)<0 ) error("Failed to read the targets: %s\n", args->af_fname); } if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); init_data(args); while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); cnv_next_line(args, line); } cnv_next_line(args, NULL); create_plots(args); fprintf(stderr,"Number of lines: total/processed: %d/%d\n", args->ntot,args->nused); destroy_data(args); free(args); return 0; } bcftools-1.21/vcfconcat.c000066400000000000000000001451041467060157400154010ustar00rootroot00000000000000/* vcfconcat.c -- Concatenate or combine VCF/BCF files. Copyright (C) 2013-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include // for hts_get_bgzfp() #include #include #include #include "bcftools.h" typedef struct _args_t { bcf_srs_t *files; htsFile *out_fh; int output_type, n_threads, record_cmd_line, clevel; bcf_hdr_t *out_hdr; int *seen_seq; char *index_fn; int write_index; // phasing int *start_pos, start_tid, ifname; int *swap_phase, nswap, *nmatch, *nmism; bcf1_t **buf; uint8_t *buf_mask; int nbuf, mbuf, prev_chr, min_PQ, prev_pos_check; int32_t *GTa, *GTb, mGTa, mGTb, *phase_qual, *phase_set; char **argv, *output_fname, *file_list, **fnames, *remove_dups, *regions_list; int argc, nfnames, allow_overlaps, phased_concat, regions_is_file, regions_overlap; int compact_PS, phase_set_changed, naive_concat, naive_concat_trust_headers; int verbose, explicit_output_type, ligate_force, ligate_warn; int sites_only; htsThreadPool *tpool; } args_t; static bcf_hdr_t *drop_hdr_genotypes(args_t *args, bcf_hdr_t *hdr) { if ( !args->sites_only ) return hdr; bcf_hdr_t *rmme = hdr; hdr = bcf_hdr_subset(rmme, 0, 0, 0); bcf_hdr_remove(hdr, BCF_HL_FMT, NULL); bcf_hdr_destroy(rmme); return hdr; } static void init_data(args_t *args) { bcf1_t *line = NULL; // With phased concat, the chunks overlap and come in the right order. To // avoid opening all files at once, store start positions to recognise need // for the next one. This way we can keep only two open chunks at once. if ( args->phased_concat ) { args->start_pos = (int*) malloc(sizeof(int)*args->nfnames); line = bcf_init(); } if ( args->verbose ) fprintf(stderr,"Checking the headers and starting positions of %d files\n", args->nfnames); kstring_t str = {0,0,0}; int i, prev_chrid = -1; for (i=0; infnames; i++) { htsFile *fp = hts_open(args->fnames[i], "r"); if ( !fp ) error("Failed to open: %s\n", args->fnames[i]); bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("Failed to parse header: %s\n", args->fnames[i]); hdr = drop_hdr_genotypes(args, hdr); args->out_hdr = bcf_hdr_merge(args->out_hdr,hdr); if ( bcf_hdr_nsamples(hdr) != bcf_hdr_nsamples(args->out_hdr) ) error("Different number of samples in %s. Perhaps \"bcftools merge\" is what you are looking for?\n", args->fnames[i]); int j; for (j=0; jout_hdr->samples[j],hdr->samples[j]) ) error("Different sample names in %s. Perhaps \"bcftools merge\" is what you are looking for?\n", args->fnames[i]); if ( args->phased_concat ) { int ret = bcf_read(fp, hdr, line); if ( ret!=0 ) args->start_pos[i] = -2; // empty file else { int chrid = bcf_hdr_id2int(args->out_hdr,BCF_DT_CTG,bcf_seqname(hdr,line)); args->start_pos[i] = chrid==prev_chrid ? line->pos : -1; prev_chrid = chrid; } } bcf_hdr_destroy(hdr); if ( hts_close(fp)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fnames[i]); } free(str.s); if ( line ) bcf_destroy(line); args->seen_seq = (int*) calloc(args->out_hdr->n[BCF_DT_CTG],sizeof(int)); if ( args->phased_concat ) { bcf_hdr_append(args->out_hdr,"##FORMAT="); bcf_hdr_append(args->out_hdr,"##FORMAT="); } if (args->record_cmd_line) bcf_hdr_append_version(args->out_hdr, args->argc, args->argv, "bcftools_concat"); char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->allow_overlaps || args->phased_concat ) { args->files = bcf_sr_init(); args->files->require_index = 1; } if ( args->n_threads ) { if ( args->files ) { if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); args->tpool = args->files->p; } else { args->tpool = (htsThreadPool*) calloc(1, sizeof(htsThreadPool)); if ( !args->tpool ) error("Failed to allocate memory\n"); if ( !(args->tpool->pool = hts_tpool_init(args->n_threads)) ) error("Failed to initialize %d threads\n",args->n_threads); } hts_set_opt(args->out_fh, HTS_OPT_THREAD_POOL, args->tpool); } if ( bcf_hdr_write(args->out_fh, args->out_hdr)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->out_hdr,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); if ( args->allow_overlaps ) { if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->remove_dups ) { if ( !strcmp(args->remove_dups,"snps") ) args->files->collapse |= COLLAPSE_SNPS; else if ( !strcmp(args->remove_dups,"indels") ) args->files->collapse |= COLLAPSE_INDELS; else if ( !strcmp(args->remove_dups,"both") ) args->files->collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; else if ( !strcmp(args->remove_dups,"any") ) args->files->collapse |= COLLAPSE_ANY; else if ( !strcmp(args->remove_dups,"all") ) args->files->collapse |= COLLAPSE_ANY; else if ( !strcmp(args->remove_dups,"none") ) args->files->collapse = COLLAPSE_NONE; else if ( !strcmp(args->remove_dups,"exact") ) args->files->collapse = COLLAPSE_NONE; else error("The -D string \"%s\" not recognised.\n", args->remove_dups); } for (i=0; infnames; i++) if ( !bcf_sr_add_reader(args->files,args->fnames[i]) ) error("Failed to open %s: %s\n", args->fnames[i],bcf_sr_strerror(args->files->errnum)); } else if ( args->phased_concat ) { // Remove empty files from the list int nok = 0; while (1) { while ( noknfnames && args->start_pos[nok]!=-2 ) nok++; if ( nok==args->nfnames ) break; i = nok; while ( infnames && args->start_pos[i]==-2 ) i++; if ( i==args->nfnames ) break; int tmp = args->start_pos[nok]; args->start_pos[nok] = args->start_pos[i]; args->start_pos[i] = tmp; char *str = args->fnames[nok]; args->fnames[nok] = args->fnames[i]; args->fnames[i] = str; } for (i=nok; infnames; i++) free(args->fnames[i]); args->nfnames = nok; for (i=1; infnames; i++) if ( args->start_pos[i-1]!=-1 && args->start_pos[i]!=-1 && args->start_pos[i]start_pos[i-1] ) error("The files not in ascending order: %d in %s, %d in %s\n", args->start_pos[i-1]+1,args->fnames[i-1],args->start_pos[i]+1,args->fnames[i]); args->prev_chr = -1; args->swap_phase = (int*) calloc(bcf_hdr_nsamples(args->out_hdr),sizeof(int)); args->nmatch = (int*) calloc(bcf_hdr_nsamples(args->out_hdr),sizeof(int)); args->nmism = (int*) calloc(bcf_hdr_nsamples(args->out_hdr),sizeof(int)); args->phase_qual = (int32_t*) malloc(bcf_hdr_nsamples(args->out_hdr)*sizeof(int32_t)); args->phase_set = (int32_t*) malloc(bcf_hdr_nsamples(args->out_hdr)*sizeof(int32_t)); args->ifname = 0; } } static void destroy_data(args_t *args) { int i; if ( args->out_fh ) { if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n",args->output_fname?args->output_fname:"stdout"); } if ( args->tpool && !args->files ) { hts_tpool_destroy(args->tpool->pool); free(args->tpool); } if ( args->files ) bcf_sr_destroy(args->files); if ( args->out_hdr ) bcf_hdr_destroy(args->out_hdr); free(args->seen_seq); free(args->start_pos); free(args->swap_phase); for (i=0; imbuf; i++) bcf_destroy(args->buf[i]); free(args->buf); free(args->buf_mask); free(args->GTa); free(args->GTb); free(args->nmatch); free(args->nmism); free(args->phase_qual); free(args->phase_set); for (i=0; infnames; i++) free(args->fnames[i]); free(args->fnames); } int vcf_write_line(htsFile *fp, kstring_t *line); #define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } static void phase_update(args_t *args, bcf_hdr_t *hdr, bcf1_t *rec) { int i, nGTs = bcf_get_genotypes(hdr, rec, &args->GTa, &args->mGTa); if ( nGTs <= 0 ) return; // GT field is not present for (i=0; iswap_phase[i] ) continue; int *gt = &args->GTa[i*2]; if ( bcf_gt_is_missing(gt[0]) || gt[1]==bcf_int32_vector_end ) continue; if ( !bcf_gt_is_phased(gt[1]) ) continue; SWAP(int, gt[0], gt[1]); gt[1] |= 1; } bcf_update_genotypes(hdr,rec,args->GTa,nGTs); } static void phased_flush(args_t *args) { if ( !args->nbuf ) return; bcf_hdr_t *ahdr = args->files->readers[0].header; bcf_hdr_t *bhdr = args->files->readers[1].header; int i, j, nsmpl = bcf_hdr_nsamples(args->out_hdr); static int gt_absent_warned = 0; for (i=0; inbuf; i+=2) { if ( args->buf_mask[i/2]!=3 ) continue; bcf1_t *arec = args->buf[i]; bcf1_t *brec = args->buf[i+1]; int nGTs = bcf_get_genotypes(ahdr, arec, &args->GTa, &args->mGTa); if ( nGTs < 0 ) { if ( !gt_absent_warned ) { fprintf(stderr,"GT is not present at %s:%"PRId64". (This warning is printed only once.)\n", bcf_seqname(ahdr,arec), (int64_t) arec->pos+1); gt_absent_warned = 1; } continue; } if ( nGTs != 2*nsmpl ) continue; // not diploid nGTs = bcf_get_genotypes(bhdr, brec, &args->GTb, &args->mGTb); if ( nGTs < 0 ) { if ( !gt_absent_warned ) { fprintf(stderr,"GT is not present at %s:%"PRId64". (This warning is printed only once.)\n", bcf_seqname(bhdr,brec), (int64_t) brec->pos+1); gt_absent_warned = 1; } continue; } if ( nGTs != 2*nsmpl ) continue; // not diploid for (j=0; jGTa[j*2]; int *gtb = &args->GTb[j*2]; if ( gta[1]==bcf_int32_vector_end || gtb[1]==bcf_int32_vector_end ) continue; if ( bcf_gt_is_missing(gta[0]) || bcf_gt_is_missing(gta[1]) || bcf_gt_is_missing(gtb[0]) || bcf_gt_is_missing(gtb[1]) ) continue; if ( !bcf_gt_is_phased(gta[1]) || !bcf_gt_is_phased(gtb[1]) ) continue; if ( bcf_gt_allele(gta[0])==bcf_gt_allele(gta[1]) || bcf_gt_allele(gtb[0])==bcf_gt_allele(gtb[1]) ) continue; if ( bcf_gt_allele(gta[0])==bcf_gt_allele(gtb[0]) && bcf_gt_allele(gta[1])==bcf_gt_allele(gtb[1]) ) { if ( args->swap_phase[j] ) args->nmism[j]++; else args->nmatch[j]++; } if ( bcf_gt_allele(gta[0])==bcf_gt_allele(gtb[1]) && bcf_gt_allele(gta[1])==bcf_gt_allele(gtb[0]) ) { if ( args->swap_phase[j] ) args->nmatch[j]++; else args->nmism[j]++; } } } for (i=0; inbuf/2; i+=2) { bcf1_t *rec; bcf_hdr_t *hdr; int mask = args->buf_mask[i/2]; if ( mask & 1 ) { rec = args->buf[i]; hdr = args->files->readers[0].header; } else { rec = args->buf[i+1]; hdr = args->files->readers[1].header; } bcf_translate(args->out_hdr, hdr, rec); if ( args->nswap && (mask&1) ) phase_update(args, args->out_hdr, rec); if ( !args->compact_PS || args->phase_set_changed ) { bcf_update_format_int32(args->out_hdr,rec,"PS",args->phase_set,nsmpl); args->phase_set_changed = 0; } if ( bcf_write(args->out_fh, args->out_hdr, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( rec->pos < args->prev_pos_check ) error("FIXME, disorder: %s:%"PRId64" vs %d [1]\n", bcf_seqname(hdr,rec),(int64_t)rec->pos+1,args->prev_pos_check+1); args->prev_pos_check = rec->pos; } args->nswap = 0; for (j=0; jnmatch[j] >= args->nmism[j] ) args->swap_phase[j] = 0; else { args->swap_phase[j] = 1; args->nswap++; } if ( args->nmatch[j] && args->nmism[j] ) { // Entropy-inspired quality. The factor 0.7 shifts and scales to (0,1) double f = (double)args->nmatch[j]/(args->nmatch[j]+args->nmism[j]); args->phase_qual[j] = 99*(0.7 + f*log(f) + (1-f)*log(1-f))/0.7; } else args->phase_qual[j] = 99; args->nmatch[j] = 0; args->nmism[j] = 0; } int PQ_printed = 0; for (; inbuf; i+=2) { bcf1_t *rec; bcf_hdr_t *hdr; int mask = args->buf_mask[i/2]; if ( mask & 2 ) { rec = args->buf[i+1]; hdr = args->files->readers[1].header; } else { rec = args->buf[i]; hdr = args->files->readers[0].header; } bcf_translate(args->out_hdr, hdr, rec); if ( !PQ_printed && mask==3 ) { bcf_update_format_int32(args->out_hdr,rec,"PQ",args->phase_qual,nsmpl); PQ_printed = 1; for (j=0; jphase_qual[j] < args->min_PQ ) { args->phase_set[j] = rec->pos+1; args->phase_set_changed = 1; } else if ( args->compact_PS ) args->phase_set[j] = bcf_int32_missing; } if ( args->nswap ) phase_update(args, args->out_hdr, rec); if ( !args->compact_PS || args->phase_set_changed ) { bcf_update_format_int32(args->out_hdr,rec,"PS",args->phase_set,nsmpl); args->phase_set_changed = 0; } if ( bcf_write(args->out_fh, args->out_hdr, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( rec->pos < args->prev_pos_check ) error("FIXME, disorder: %s:%"PRId64" vs %d [2]\n", bcf_seqname(hdr,rec),(int64_t)rec->pos+1,args->prev_pos_check+1); args->prev_pos_check = rec->pos; } args->nbuf = 0; } static void phased_push(args_t *args, bcf1_t *arec, bcf1_t *brec, int is_overlap) { bcf_hdr_t *ahdr = arec ? bcf_sr_get_header(args->files,0) : NULL; bcf_hdr_t *bhdr = brec ? bcf_sr_get_header(args->files,1) : NULL; if ( arec && arec->errcode ) error("Parse error at %s:%"PRId64", cannot proceed: %s\n", bcf_seqname(ahdr,arec),(int64_t) arec->pos+1, args->files->readers[0].fname); if ( brec && brec->errcode ) error("Parse error at %s:%"PRId64", cannot proceed: %s\n", bcf_seqname(bhdr,brec),(int64_t) brec->pos+1, args->files->readers[1].fname); int i, nsmpl = bcf_hdr_nsamples(args->out_hdr); int chr_id = arec ? bcf_hdr_name2id(args->out_hdr,bcf_seqname(ahdr,arec)) : bcf_hdr_name2id(args->out_hdr,bcf_seqname(bhdr,brec)); if ( args->prev_chr<0 || args->prev_chr!=chr_id ) { if ( args->prev_chr>=0 ) phased_flush(args); for (i=0; iphase_set[i] = arec ? arec->pos+1 : brec->pos+1; args->phase_set_changed = 1; if ( args->seen_seq[chr_id] ) error("The chromosome block %s is not contiguous\n", arec ? bcf_seqname(ahdr,arec) : bcf_seqname(bhdr,brec)); args->seen_seq[chr_id] = 1; args->prev_chr = chr_id; args->prev_pos_check = -1; } if ( !is_overlap ) { assert(arec); bcf_translate(args->out_hdr, ahdr, arec); if ( args->nswap ) phase_update(args, args->out_hdr, arec); if ( !args->compact_PS || args->phase_set_changed ) { bcf_update_format_int32(args->out_hdr,arec,"PS",args->phase_set,nsmpl); args->phase_set_changed = 0; } if ( bcf_write(args->out_fh, args->out_hdr, arec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( arec->pos < args->prev_pos_check ) error("FIXME, disorder: %s:%"PRId64" in %s vs %d written [3]\n", bcf_seqname(ahdr,arec), (int64_t) arec->pos+1,args->files->readers[0].fname, args->prev_pos_check+1); args->prev_pos_check = arec->pos; return; } int m = args->mbuf; args->nbuf += 2; hts_expand(bcf1_t*,args->nbuf,args->mbuf,args->buf); if ( m < args->mbuf ) args->buf_mask = (uint8_t*)realloc(args->buf_mask,sizeof(*args->buf_mask)*args->mbuf); for (i=m; imbuf; i++) args->buf[i] = bcf_init1(); if ( arec ) SWAP(bcf1_t*, args->files->readers[0].buffer[0], args->buf[args->nbuf-2]); if ( brec ) SWAP(bcf1_t*, args->files->readers[1].buffer[0], args->buf[args->nbuf-1]); args->buf_mask[args->nbuf/2-1] = (arec?1:0) | (brec?2:0); } static int _get_active_index(bcf_srs_t *sr) { int i; for (i=0; inreaders; i++) if ( bcf_sr_has_line(sr,i) ) return i; return -1; } static void concat(args_t *args) { static int site_drop_warned = 0; int i; if ( args->phased_concat ) // phased concat { // keep only two open files at a time while ( args->ifname < args->nfnames ) { int new_file = 0; while ( args->files->nreaders < 2 && args->ifname < args->nfnames ) { if ( !bcf_sr_add_reader(args->files,args->fnames[args->ifname]) ) error("Failed to open %s: %s\n", args->fnames[args->ifname],bcf_sr_strerror(args->files->errnum)); new_file = 1; args->ifname++; if ( args->start_pos[args->ifname-1]==-1 ) break; // new chromosome, start with only one file open if ( args->ifname < args->nfnames && args->start_pos[args->ifname]==-1 ) break; // next file starts on a different chromosome } // is there a line from the previous run? Seek the newly opened reader to that position int seek_pos = -1; int seek_chr = -1; if ( bcf_sr_has_line(args->files,0) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); bcf_sr_seek(args->files, bcf_seqname(args->files->readers[0].header,line), line->pos); seek_pos = line->pos; seek_chr = bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[0].header,line)); } else if ( new_file ) bcf_sr_seek(args->files,NULL,0); // set to start int nret, ir; while ( (nret = bcf_sr_next_line(args->files)) ) { int is_overlap = args->files->nreaders==1 ? 0 : 1; if ( !bcf_sr_has_line(args->files,0) ) // no input from the first reader { // We are assuming that there is a perfect overlap, sites which are not present in both files are dropped if ( bcf_sr_region_done(args->files,0) ) { phased_flush(args); bcf_sr_remove_reader(args->files, 0); is_overlap = 0; } else if ( args->ligate_warn ) { if ( !site_drop_warned ) { ir = _get_active_index(args->files); fprintf(stderr, "Warning: Dropping the site %s:%"PRId64". The --ligate option is intended for VCFs with perfect\n" " overlap, sites in overlapping regions present in one but missing in other are dropped.\n" " This warning is printed only once.\n", bcf_seqname(bcf_sr_get_header(args->files,ir),bcf_sr_get_line(args->files,ir)), (int64_t) bcf_sr_get_line(args->files,ir)->pos+1); site_drop_warned = 1; } continue; } else if ( !args->ligate_force ) { ir = _get_active_index(args->files); error("Error: The --ligate option is intended for VCFs with perfect overlap, the site %s:%"PRId64" breaks the assumption\n", bcf_seqname(bcf_sr_get_header(args->files,ir),bcf_sr_get_line(args->files,ir)), (int64_t) bcf_sr_get_line(args->files,ir)->pos+1); } } // Get a line to learn about current position ir = _get_active_index(args->files); bcf1_t *line = bcf_sr_get_line(args->files,ir); // This can happen after bcf_sr_seek: indel may start before the coordinate which we seek to. if ( seek_chr>=0 && seek_pos>line->pos && seek_chr==bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[ir].header,line)) ) continue; seek_pos = seek_chr = -1; // Check if the position overlaps with the next, yet unopened, reader int must_seek = 0; while ( args->ifname < args->nfnames && args->start_pos[args->ifname]!=-1 && line->pos >= args->start_pos[args->ifname] ) { must_seek = 1; if ( !bcf_sr_add_reader(args->files,args->fnames[args->ifname]) ) error("Failed to open %s: %s\n", args->fnames[args->ifname],bcf_sr_strerror(args->files->errnum)); args->ifname++; } if ( must_seek ) { bcf_sr_seek(args->files, bcf_seqname(args->files->readers[ir].header,line), line->pos); seek_pos = line->pos; seek_chr = bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[ir].header,line)); continue; } // We are assuming that there is a perfect overlap, sites which are not present in both files are dropped if ( args->files->nreaders>1 && !bcf_sr_has_line(args->files,1) && !bcf_sr_region_done(args->files,1) && !args->ligate_force ) { if ( args->ligate_warn && !site_drop_warned ) { ir = _get_active_index(args->files); fprintf(stderr, "Warning: Dropping the site %s:%"PRId64". The --ligate option is intended for VCFs with perfect\n" " overlap, sites in overlapping regions present in one but missing in other are dropped.\n" " This warning is printed only once.\n", bcf_seqname(bcf_sr_get_header(args->files,ir),line), (int64_t) line->pos+1); site_drop_warned = 1; } else if ( !args->ligate_warn ) { ir = _get_active_index(args->files); error("Error: The --ligate option is intended for VCFs with perfect overlap, the site %s:%"PRId64" breaks the assumption\n", bcf_seqname(bcf_sr_get_header(args->files,ir),bcf_sr_get_line(args->files,ir)), (int64_t) bcf_sr_get_line(args->files,ir)->pos+1); } continue; } bcf1_t *line0 = bcf_sr_get_line(args->files,0); bcf1_t *line1 = args->files->nreaders > 1 ? bcf_sr_get_line(args->files,1) : NULL; phased_push(args, line0, line1, is_overlap); } if ( args->files->nreaders ) { phased_flush(args); while ( args->files->nreaders ) bcf_sr_remove_reader(args->files, 0); } } } else if ( args->files ) // combining overlapping files, using synced reader { while ( bcf_sr_next_line(args->files) ) { for (i=0; ifiles->nreaders; i++) { bcf1_t *line = bcf_sr_get_line(args->files,i); if ( !line ) continue; if ( args->sites_only ) bcf_subset(args->out_hdr, line, 0, 0); bcf_translate(args->out_hdr, args->files->readers[i].header, line); if ( bcf_write1(args->out_fh, args->out_hdr, line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( args->remove_dups ) break; } } } else // concatenate as is { struct timeval t0, t1; kstring_t tmp = {0,0,0}; int prev_chr_id = -1, prev_pos; bcf1_t *line = bcf_init(); for (i=0; infnames; i++) { if ( args->verbose ) { fprintf(stderr,"Concatenating %s", args->fnames[i]); gettimeofday(&t0, NULL); } htsFile *fp = hts_open(args->fnames[i], "r"); if ( !fp ) error("\nFailed to open: %s\n", args->fnames[i]); if ( args->n_threads ) hts_set_opt(fp, HTS_OPT_THREAD_POOL, args->tpool); bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("\nFailed to parse header: %s\n", args->fnames[i]); if ( args->sites_only ) { bcf_hdr_t *hdr_ori = hdr; hdr = bcf_hdr_subset(hdr_ori, 0, 0, 0); bcf_hdr_remove(hdr, BCF_HL_FMT, NULL); bcf_hdr_destroy(hdr_ori); } if ( !fp->is_bin && args->output_type&FT_VCF ) { line->max_unpack = BCF_UN_STR; // if VCF is on both input and output, avoid VCF to BCF conversion while ( hts_getline(fp, KS_SEP_LINE, &fp->line) >=0 ) { char *str = fp->line.s; // remove genotypes if ( args->sites_only ) { int ntab = 0; while ( *str ) { if ( *str == '\t' && ++ntab==8 ) { *str = 0; break; } str++; } str = fp->line.s; } while ( *str && *str!='\t' ) str++; tmp.l = 0; kputsn(fp->line.s,str-fp->line.s,&tmp); int chr_id = bcf_hdr_name2id(args->out_hdr, tmp.s); if ( chr_id<0 ) error("\nThe sequence \"%s\" not defined in the header: %s\n(Quick workaround: index the file.)\n", tmp.s, args->fnames[i]); if ( prev_chr_id!=chr_id ) { prev_pos = -1; if ( args->seen_seq[chr_id] ) error("\nThe chromosome block %s is not contiguous, consider running with -a.\n", tmp.s); } char *end; int pos = strtol(str+1,&end,10) - 1; if ( end==str+1 ) error("Could not parse line: %s\n", fp->line.s); if ( prev_pos > pos ) error("\nThe chromosome block %s is not sorted, consider running with -a.\n", tmp.s); args->seen_seq[chr_id] = 1; prev_chr_id = chr_id; if ( vcf_write_line(args->out_fh, &fp->line)!=0 ) error("\nFailed to write %"PRIu64" bytes\n", (uint64_t)fp->line.l); } } else { // BCF conversion is required line->max_unpack = 0; while ( bcf_read(fp, hdr, line)==0 ) { if ( args->sites_only ) bcf_subset(args->out_hdr, line, 0, 0); bcf_translate(args->out_hdr, hdr, line); if ( prev_chr_id!=line->rid ) { prev_pos = -1; if ( args->seen_seq[line->rid] ) error("\nThe chromosome block %s is not contiguous, consider running with -a.\n", bcf_seqname(args->out_hdr, line)); } if ( prev_pos > line->pos ) error("\nThe chromosome block %s is not sorted, consider running with -a.\n", bcf_seqname(args->out_hdr, line)); args->seen_seq[line->rid] = 1; prev_chr_id = line->rid; if ( bcf_write(args->out_fh, args->out_hdr, line)!=0 ) error("\nFailed to write\n"); } } bcf_hdr_destroy(hdr); hts_close(fp); if ( args->verbose ) { gettimeofday(&t1, NULL); double delta = (t1.tv_sec - t0.tv_sec) * 1e6 + (t1.tv_usec - t0.tv_usec); fprintf(stderr,"\t%f seconds\n",delta/1e6); } } bcf_destroy(line); free(tmp.s); } } int print_vcf_gz_header(BGZF *fp, BGZF *bgzf_out, int print_header, kstring_t *tmp) { char *buffer = (char*) fp->uncompressed_block; // Read the header and find the position of the data block if ( buffer[0]!='#' ) error("Could not parse the header, expected '#', found '%c'\n", buffer[0]); int nskip = 1; // end of the header in the current uncompressed block while (1) { if ( buffer[nskip]=='\n' ) { nskip++; if ( nskip>=fp->block_length ) { kputsn(buffer,nskip,tmp); if ( bgzf_read_block(fp) != 0 ) return -1; if ( !fp->block_length ) break; nskip = 0; } // The header has finished if ( buffer[nskip]!='#' ) { kputsn(buffer,nskip,tmp); break; } } nskip++; if ( nskip>=fp->block_length ) { kputsn(buffer,fp->block_length,tmp); if ( bgzf_read_block(fp) != 0 ) return -1; if ( !fp->block_length ) break; nskip = 0; } } if ( print_header ) { if ( bgzf_write(bgzf_out,tmp->s,tmp->l) != tmp->l ) error("Failed to write %"PRIu64" bytes\n", (uint64_t)tmp->l); tmp->l = 0; } return nskip; } static inline int unpackInt16(const uint8_t *buffer) { return buffer[0] | buffer[1] << 8; } static int check_header(const uint8_t *header) { if ( header[0] != 31 || header[1] != 139 || header[2] != 8 ) return -2; return ((header[3] & 4) != 0 && unpackInt16((uint8_t*)&header[10]) == 6 && header[12] == 'B' && header[13] == 'C' && unpackInt16((uint8_t*)&header[14]) == 2) ? 0 : -1; } static void _check_hrecs(const bcf_hdr_t *hdr0, const bcf_hdr_t *hdr, char *fname0, char *fname) { int j; for (j=0; jnhrec; j++) { bcf_hrec_t *hrec0 = hdr0->hrec[j]; if ( hrec0->type!=BCF_HL_FLT && hrec0->type!=BCF_HL_INFO && hrec0->type!=BCF_HL_FMT && hrec0->type!=BCF_HL_CTG ) continue; // skip fields w/o IDX int itag = bcf_hrec_find_key(hrec0, "ID"); bcf_hrec_t *hrec = bcf_hdr_get_hrec(hdr, hrec0->type, "ID", hrec0->vals[itag], NULL); char *type = NULL; if ( hrec0->type==BCF_HL_FLT ) type = "FILTER"; if ( hrec0->type==BCF_HL_INFO ) type = "INFO"; if ( hrec0->type==BCF_HL_FMT ) type = "FORMAT"; if ( hrec0->type==BCF_HL_CTG ) type = "contig"; if ( !hrec ) error("Cannot use --naive, incompatible headers, the tag %s/%s not present in %s\n",type,hrec0->vals[itag],fname); int idx0 = bcf_hrec_find_key(hrec0, "IDX"); int idx = bcf_hrec_find_key(hrec, "IDX"); if ( idx0<0 || idx<0 ) error("fixme: unexpected IDX<0 for %s/%s in %s or %s\n",type,hrec0->vals[itag],fname0,fname); if ( strcmp(hrec0->vals[idx0],hrec->vals[idx]) ) error("Cannot use --naive, use --naive-force instead: different order the tag %s/%s in %s vs %s\n",type,hrec0->vals[itag],fname0,fname); } } static void naive_concat_check_headers(args_t *args) { fprintf(stderr,"Checking the headers of %d files.\n",args->nfnames); bcf_hdr_t *hdr0 = NULL; int i,j; for (i=0; infnames; i++) { htsFile *fp = hts_open(args->fnames[i], "r"); if ( !fp ) error("Failed to open: %s\n", args->fnames[i]); bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("Failed to parse header: %s\n", args->fnames[i]); htsFormat type = *hts_get_format(fp); hts_close(fp); if ( i==0 ) { hdr0 = hdr; continue; } // check the samples if ( bcf_hdr_nsamples(hdr0)!=bcf_hdr_nsamples(hdr) ) error("Cannot concatenate, different number of samples: %d vs %d in %s vs %s\n",bcf_hdr_nsamples(hdr0),bcf_hdr_nsamples(hdr),args->fnames[0],args->fnames[i]); for (j=0; jsamples[j],hdr->samples[j]) ) error("Cannot concatenate, different samples in %s vs %s\n",args->fnames[0],args->fnames[i]); // if BCF, check if tag IDs are consistent in the dictionary of strings if ( type.compression!=bgzf ) error("The --naive option works only for compressed BCFs or VCFs, sorry :-/\n"); _check_hrecs(hdr0,hdr,args->fnames[0],args->fnames[i]); _check_hrecs(hdr,hdr0,args->fnames[i],args->fnames[0]); bcf_hdr_destroy(hdr); } if ( hdr0 ) bcf_hdr_destroy(hdr0); fprintf(stderr,"Done, the headers are compatible.\n"); } static void naive_concat(args_t *args) { if ( !args->naive_concat_trust_headers ) naive_concat_check_headers(args); // only compressed BCF atm BGZF *bgzf_out = bgzf_open(args->output_fname,"w");; htsFormat output_type; output_type.format = (args->output_type & FT_VCF) ? vcf : bcf; output_type.compression = (args->output_type & FT_GZ) ? bgzf : no_compression; struct timeval t0, t1; const size_t page_size = BGZF_MAX_BLOCK_SIZE; uint8_t *buf = (uint8_t*) malloc(page_size); kstring_t tmp = {0,0,0}; int i, file_types = 0; for (i=0; infnames; i++) { if ( args->verbose ) { fprintf(stderr,"Concatenating %s", args->fnames[i]); gettimeofday(&t0, NULL); } htsFile *hts_fp = hts_open(args->fnames[i],"r"); if ( !hts_fp ) error("\nFailed to open: %s\n", args->fnames[i]); htsFormat type = *hts_get_format(hts_fp); if ( type.compression!=bgzf ) error("\nThe --naive option works only for compressed BCFs or VCFs\n"); file_types |= type.format==vcf ? 1 : 2; if ( file_types==3 ) error("\nThe --naive option works only for compressed files of the same type, all BCFs or all VCFs\n"); if ( args->explicit_output_type ) { if ( output_type.format!=type.format ) error("\nThe --naive option works only for the output of the same type, all BCFs or all VCFs\n"); if ( output_type.compression!=type.compression ) error("\nThe --naive option works only for the output of the same compression type\n"); } BGZF *fp = hts_get_bgzfp(hts_fp); if ( !fp || bgzf_read_block(fp) != 0 || !fp->block_length ) error("\nFailed to read %s: %s\n", args->fnames[i], strerror(errno)); int nskip; if ( type.format==bcf ) { const size_t magic_len = 5 + 4; // "Magic" string + header length uint8_t magic[magic_len]; if ( bgzf_read(fp, magic, magic_len) != magic_len ) error("\nFailed to read the BCF header in %s\n", args->fnames[i]); // First five bytes are the "Magic" string if (strncmp((char*)magic, "BCF\2\2", 5) != 0) error("\nInvalid BCF magic string in %s\n", args->fnames[i]); // Next four are the header length (little-endian) tmp.l = le_to_u32(magic + 5); hts_expand(char,tmp.l,tmp.m,tmp.s); if ( bgzf_read(fp, tmp.s, tmp.l) != tmp.l ) error("\nFailed to read the BCF header in %s\n", args->fnames[i]); // write only the first header if ( i==0 ) { if ( bgzf_write(bgzf_out, magic, magic_len) != magic_len ) error("\nFailed to write %zu bytes to %s\n", magic_len,args->output_fname); if ( bgzf_write(bgzf_out, tmp.s, tmp.l) != tmp.l) error("\nFailed to write %"PRId64" bytes to %s\n", (uint64_t)tmp.l,args->output_fname); } nskip = fp->block_offset; } else { nskip = print_vcf_gz_header(fp, bgzf_out, i==0?1:0, &tmp); if ( nskip==-1 ) error("\nError reading %s\n", args->fnames[i]); } // Output all non-header data that were read together with the header block if ( fp->block_length - nskip > 0 ) { if ( bgzf_write(bgzf_out, (char *)fp->uncompressed_block+nskip, fp->block_length-nskip)<0 ) error("\nError: %d\n",fp->errcode); } if ( bgzf_flush(bgzf_out)<0 ) error("\nError: %d\n",bgzf_out->errcode); // Stream the rest of the file as it is, without recompressing, but remove BGZF EOF blocks // The final bgzf eof block will be added by bgzf_close. ssize_t nread, nblock, nwr; const int nheader = 18, neof = 28; const uint8_t *eof = (uint8_t*) "\037\213\010\4\0\0\0\0\0\377\6\0\102\103\2\0\033\0\3\0\0\0\0\0\0\0\0\0"; while (1) { nread = bgzf_raw_read(fp, buf, nheader); if ( !nread ) break; if ( nread != nheader || check_header(buf)!=0 ) error("\nCould not parse the header of a bgzf block: %s\n",args->fnames[i]); nblock = unpackInt16(buf+16) + 1; assert( nblock <= page_size && nblock >= nheader ); nread += bgzf_raw_read(fp, buf+nheader, nblock - nheader); if ( nread!=nblock ) error("\nCould not read %"PRId64" bytes: %s\n",(uint64_t)nblock,args->fnames[i]); if ( nread==neof && !memcmp(buf,eof,neof) ) continue; nwr = bgzf_raw_write(bgzf_out, buf, nread); if ( nwr != nread ) error("\nWrite failed, wrote %"PRId64" instead of %d bytes.\n", (uint64_t)nwr,(int)nread); } if (hts_close(hts_fp)) error("\nClose failed: %s\n",args->fnames[i]); if ( args->verbose ) { gettimeofday(&t1, NULL); double delta = (t1.tv_sec - t0.tv_sec) * 1e6 + (t1.tv_usec - t0.tv_usec); fprintf(stderr,"\t%f seconds\n",delta/1e6); } } free(buf); free(tmp.s); if (bgzf_close(bgzf_out) < 0) error("Error: %d\n",bgzf_out->errcode); } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Concatenate or combine VCF/BCF files. All source files must have the same sample\n"); fprintf(stderr, " columns appearing in the same order. The program can be used, for example, to\n"); fprintf(stderr, " concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel\n"); fprintf(stderr, " VCF into one. The input files must be sorted by chr and position. The files\n"); fprintf(stderr, " must be given in the correct order to produce sorted VCF on output unless\n"); fprintf(stderr, " the -a, --allow-overlaps option is specified. With the --naive option, the files\n"); fprintf(stderr, " are concatenated without being recompressed, which is very fast.\n"); fprintf(stderr, "Usage: bcftools concat [options] [ [...]]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -a, --allow-overlaps First coordinate of the next file can precede last record of the current file.\n"); fprintf(stderr, " -c, --compact-PS Do not output PS tag at each site, only at the start of a new phase set block.\n"); fprintf(stderr, " -d, --rm-dups STRING Output duplicate records present in multiple files only once: \n"); fprintf(stderr, " -D, --remove-duplicates Alias for -d exact\n"); fprintf(stderr, " -f, --file-list FILE Read the list of files from a file.\n"); fprintf(stderr, " -G, --drop-genotypes Drop individual genotype information.\n"); fprintf(stderr, " -l, --ligate Ligate phased VCFs by matching phase at overlapping haplotypes\n"); fprintf(stderr, " --ligate-force Ligate even non-overlapping chunks, keep all sites\n"); fprintf(stderr, " --ligate-warn Drop sites in imperfect overlaps\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -n, --naive Concatenate files without recompression, a header check compatibility is performed\n"); fprintf(stderr, " --naive-force Same as --naive, but header compatibility is not checked. Dangerous, use with caution.\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " -q, --min-PQ INT Break phase set if phasing quality is lower than [30]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " --threads INT Use multithreading with worker threads [0]\n"); fprintf(stderr, " -v, --verbose 0|1 Set verbosity level [1]\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfconcat(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->min_PQ = 30; args->verbose = 1; args->clevel = -1; static struct option loptions[] = { {"verbose",required_argument,NULL,'v'}, {"naive",no_argument,NULL,'n'}, {"naive-force",no_argument,NULL,7}, {"compact-PS",no_argument,NULL,'c'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,12}, {"remove-duplicates",no_argument,NULL,'D'}, {"rm-dups",required_argument,NULL,'d'}, {"allow-overlaps",no_argument,NULL,'a'}, {"ligate",no_argument,NULL,'l'}, {"ligate-force",no_argument,NULL,10}, {"ligate-warn",no_argument,NULL,11}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"file-list",required_argument,NULL,'f'}, {"min-PQ",required_argument,NULL,'q'}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {"drop-genotypes",no_argument,NULL,'G'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "h:?o:O:f:alq:Dd:Gr:R:cnv:W::",loptions,NULL)) >= 0) { switch (c) { case 'c': args->compact_PS = 1; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; case 'd': args->remove_dups = optarg; break; case 'D': args->remove_dups = "exact"; break; case 'q': args->min_PQ = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --min-PQ %s\n", optarg); break; case 'n': args->naive_concat = 1; break; case 'a': args->allow_overlaps = 1; break; case 'l': args->phased_concat = 1; break; case 'f': args->file_list = optarg; break; case 'G': args->sites_only = 1; break; case 'o': args->output_fname = optarg; break; case 'O': args->explicit_output_type = 1; switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 10 : args->ligate_force = 1; break; case 11 : args->ligate_warn = 1; break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 7 : args->naive_concat = 1; args->naive_concat_trust_headers = 1; break; case 12 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 'v': args->verbose = strtol(optarg, &tmp, 0); if ( *tmp || args->verbose<0 || args->verbose>1 ) error("Error: currently only --verbose 0 or --verbose 1 is supported\n"); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } while ( optindnfnames++; args->fnames = (char **)realloc(args->fnames,sizeof(char*)*args->nfnames); args->fnames[args->nfnames-1] = strdup(argv[optind]); optind++; } if ( args->ligate_force && args->ligate_warn ) error("The options cannot be combined: --ligate-force and --ligate-warn\n"); if ( args->allow_overlaps && args->phased_concat ) error("The options -a and -l should not be combined. Please run with -l only.\n"); if ( args->sites_only && args->phased_concat ) error("The options --drop-genotypes and --ligate cannot be combined\n"); if ( args->compact_PS && !args->phased_concat ) error("The -c option is intended only with -l\n"); if ( args->file_list ) { if ( args->nfnames ) error("Cannot combine -l with file names on command line.\n"); args->fnames = hts_readlines(args->file_list, &args->nfnames); if ( !args->fnames ) error("Could not read the file: %s\n", args->file_list); } if ( !args->nfnames ) usage(args); if ( args->remove_dups && !args->allow_overlaps ) error("The -D option is supported only with -a\n"); if ( args->regions_list && !args->allow_overlaps ) error("The -r/-R option is supported only with -a\n"); if ( args->naive_concat ) { if ( args->write_index ) error("Error: cannot --write-index in the %s mode\n",args->naive_concat_trust_headers?"--naive-force":"--naive"); if ( args->allow_overlaps ) error("The option --naive cannot be combined with --allow-overlaps\n"); if ( args->phased_concat ) error("The option --naive cannot be combined with --ligate\n"); if ( args->sites_only ) error("The option --naive cannot be combined with --drop-genotypes\n"); naive_concat(args); destroy_data(args); free(args); return 0; } init_data(args); concat(args); destroy_data(args); free(args); return 0; } bcftools-1.21/vcfconvert.c000066400000000000000000002207631467060157400156170ustar00rootroot00000000000000/* vcfconvert.c -- convert between VCF/BCF and related formats. Copyright (C) 2013-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "convert.h" #include "tsv2vcf.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct _args_t args_t; struct _args_t { faidx_t *ref; filter_t *filter; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE convert_t *convert; bcf_srs_t *files; bcf_hdr_t *header; void (*convert_func)(struct _args_t *); struct { int total, skipped, hom_rr, het_ra, hom_aa, het_aa, missing, written; } n; kstring_t str; int32_t *gts; float *flt; int rev_als, output_vcf_ids, hap2dip, gen_3N6; int nsamples, *samples, sample_is_file, targets_is_file, regions_is_file, output_type; int regions_overlap, targets_overlap; char **argv, *sample_list, *targets_list, *regions_list, *tag, *columns; char *outfname, *infname, *ref_fname, *sex_fname; int argc, n_threads, record_cmd_line, keep_duplicates, clevel; char *index_fn; int write_index; struct { kstring_t ref,alt,refalt; } tsv; }; static void destroy_data(args_t *args) { if ( args->ref ) fai_destroy(args->ref); if ( args->convert) convert_destroy(args->convert); if ( args->filter ) filter_destroy(args->filter); free(args->samples); if ( args->files ) bcf_sr_destroy(args->files); } static void open_vcf(args_t *args, const char *format_str) { args->files = bcf_sr_init(); if ( args->n_threads && bcf_sr_set_threads(args->files, args->n_threads)!=0 ) error("Could not initialize --threads %d\n", args->n_threads); if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( !bcf_sr_add_reader(args->files, args->infname) ) error("Failed to open %s: %s\n", args->infname,bcf_sr_strerror(args->files->errnum)); args->header = args->files->readers[0].header; if ( args->filter_str ) args->filter = filter_init(args->header, args->filter_str); int i, nsamples = 0, *samples = NULL; if ( args->sample_list && strcmp("-",args->sample_list) ) { for (i=0; ifiles->nreaders; i++) { int ret = bcf_hdr_set_samples(args->files->readers[i].header,args->sample_list,args->sample_is_file); if ( ret<0 ) error("Error parsing the sample list\n"); else if ( ret>0 ) error("Sample name mismatch: sample #%d not found in the header\n", ret); } if ( args->sample_list[0]!='^' ) { // the sample ordering may be different if not negated int n; char **smpls = hts_readlist(args->sample_list, args->sample_is_file, &n); if ( !smpls ) error("Could not parse %s\n", args->sample_list); if ( n!=bcf_hdr_nsamples(args->files->readers[0].header) ) error("The number of samples does not match, perhaps some are present multiple times?\n"); nsamples = bcf_hdr_nsamples(args->files->readers[0].header); samples = (int*) malloc(sizeof(int)*nsamples); for (i=0; ifiles->readers[0].header, BCF_DT_SAMPLE,smpls[i]); free(smpls[i]); } free(smpls); } } if ( format_str ) args->convert = convert_init(args->header, samples, nsamples, format_str); free(samples); } static int _set_ref_alt(args_t *args, bcf1_t *rec) { args->tsv.refalt.l = 0; kputs(args->tsv.ref.s, &args->tsv.refalt); if ( strcmp(".",args->tsv.alt.s) && strcmp(args->tsv.ref.s,args->tsv.alt.s) ) { kputc(',', &args->tsv.refalt); kputs(args->tsv.alt.s, &args->tsv.refalt); } bcf_update_alleles_str(args->header, rec, args->tsv.refalt.s); args->tsv.ref.l = 0; args->tsv.alt.l = 0; args->tsv.refalt.l = 0; return 0; } static int tsv_setter_ref(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; kputsn(tsv->ss,tsv->se - tsv->ss,&args->tsv.ref); if ( args->tsv.alt.l ) return _set_ref_alt(args,rec); return 0; } static int tsv_setter_alt(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; kputsn(tsv->ss,tsv->se - tsv->ss,&args->tsv.alt); if ( args->tsv.ref.l ) return _set_ref_alt(args,rec); return 0; } // Try to set CHROM:POS_REF_ALT[_END]. Return 0 on success, -1 on error static int _set_chrom_pos_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; char tmp, *se = tsv->ss, *ss = tsv->ss; while ( se < tsv->se && *se!=':' ) se++; if ( *se!=':' ) return -1; tmp = *se; *se = 0; int rid = bcf_hdr_name2id(args->header,ss); *se = tmp; if ( rid<0 ) return -1; // POS hts_pos_t pos = strtol(se+1,&ss,10); if ( ss==se+1 ) return -1; pos--; // REF,ALT args->str.l = 0; se = ++ss; while ( se < tsv->se && *se!='_' ) se++; if ( *se!='_' ) return -1; kputsn(ss,se-ss,&args->str); ss = ++se; while ( se < tsv->se && *se!='_' && isspace(*tsv->se) ) se++; if ( se < tsv->se && *se!='_' && isspace(*tsv->se) ) return -1; kputc(',',&args->str); kputsn(ss,se-ss,&args->str); // END - optional if (*se && *se=='_') { long end = strtol(se+1,&ss,10); if ( ss==se+1 ) return -1; if (end < 1 || end > INT32_MAX) return -1; int32_t e = end; // bcf_update_info_int32 needs an int32_t pointer bcf_update_info_int32(args->header, rec, "END", &e, 1); } rec->rid = rid; rec->pos = pos; bcf_update_alleles_str(args->header, rec, args->str.s); return 0; } static int tsv_setter_chrom_pos_ref_alt_or_chrom(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*)usr; int ret = _set_chrom_pos_ref_alt(tsv,rec,usr); if ( !ret ) return ret; return tsv_setter_chrom(tsv,rec,args->header); } static int tsv_setter_chrom_pos_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr) { int ret = _set_chrom_pos_ref_alt(tsv,rec,usr); if ( ret!=0 ) error("Could not parse the CHROM:POS_REF_ALT[_END] string: %s\n", tsv->ss); return ret; } // This function must be called first, then tsv_setter_chrom_pos_ref_alt_id_or_die. // One of them is expected to find the CHROM:POS_REF_ALT[_END] string, if not, die. static int tsv_setter_chrom_pos_ref_alt_or_id(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*)usr; if ( _set_chrom_pos_ref_alt(tsv,rec,usr)==0 ) return 0; rec->pos = -1; // mark the record as unset if ( !args->output_vcf_ids) return 0; return tsv_setter_id(tsv,rec,usr); } static int tsv_setter_chrom_pos_ref_alt_id_or_die(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*)usr; if ( rec->pos!=-1 ) { if ( !args->output_vcf_ids ) return 0; return tsv_setter_id(tsv,rec,usr); } return tsv_setter_chrom_pos_ref_alt(tsv,rec,usr); } static int tsv_setter_verify_pos(tsv_t *tsv, bcf1_t *rec, void *usr) { char *se; int pos = strtol(tsv->ss,&se,10); if ( tsv->ss==se ) error("Could not parse POS: %s\n", tsv->ss); if ( rec->pos != pos-1 ) error("POS mismatch: %s\n", tsv->ss); return 0; } static int tsv_setter_verify_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; args->rev_als = 0; char tmp = *tsv->se; *tsv->se = 0; if ( strcmp(tsv->ss,rec->d.allele[0]) ) { if ( strcmp(tsv->ss,rec->d.allele[1]) ) { *tsv->se = tmp; error("REF/ALT mismatch: [%s][%s]\n", tsv->ss,rec->d.allele[1]); } args->rev_als = 1; } *tsv->se = tmp; while ( *tsv->se && isspace(*tsv->se) ) tsv->se++; tsv->ss = tsv->se; while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; tmp = *tsv->se; *tsv->se = 0; if ( !args->rev_als && strcmp(tsv->ss,rec->d.allele[1]) ) { *tsv->se = tmp; error("REF/ALT mismatch: [%s][%s]\n", tsv->ss,rec->d.allele[1]); } else if ( args->rev_als && strcmp(tsv->ss,rec->d.allele[0]) ) { *tsv->se = tmp; error("REF/ALT mismatch: [%s][%s]\n", tsv->ss,rec->d.allele[0]); } *tsv->se = tmp; return 0; } static int tsv_setter_gt_gp(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; int i, nsamples = bcf_hdr_nsamples(args->header); for (i=0; iss, &tsv->se); if ( tsv->ss==tsv->se ) { fprintf(stderr,"Could not parse first value of %d-th sample\n", i+1); return -1; } tsv->ss = tsv->se+1; ab = strtod(tsv->ss, &tsv->se); if ( tsv->ss==tsv->se ) { fprintf(stderr,"Could not parse second value of %d-th sample\n", i+1); return -1; } tsv->ss = tsv->se+1; bb = strtod(tsv->ss, &tsv->se); if ( tsv->ss==tsv->se ) { fprintf(stderr,"Could not parse third value of %d-th sample\n", i+1); return -1; } tsv->ss = tsv->se+1; if ( args->rev_als ) { float tmp = bb; bb = aa; aa = tmp; } args->flt[3*i+0] = aa; args->flt[3*i+1] = ab; args->flt[3*i+2] = bb; if ( aa >= ab ) { if ( aa >= bb ) args->gts[2*i+0] = args->gts[2*i+1] = bcf_gt_unphased(0); else args->gts[2*i+0] = args->gts[2*i+1] = bcf_gt_unphased(1); } else if ( ab >= bb ) { args->gts[2*i+0] = bcf_gt_unphased(0); args->gts[2*i+1] = bcf_gt_unphased(1); } else args->gts[2*i+0] = args->gts[2*i+1] = bcf_gt_unphased(1); } if ( *tsv->se ) error("Could not parse: %s\n", tsv->ss); if ( bcf_update_genotypes(args->header,rec,args->gts,nsamples*2) ) error("Could not update GT field\n"); if ( bcf_update_format_float(args->header,rec,"GP",args->flt,nsamples*3) ) error("Could not update GP field\n"); return 0; } static int tsv_setter_haps(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; int i, nsamples = bcf_hdr_nsamples(args->header); int32_t a0, a1; if ( args->rev_als ) { a0 = bcf_gt_phased(1); a1 = bcf_gt_phased(0); } else { a0 = bcf_gt_phased(0); a1 = bcf_gt_phased(1); } // up is short for "unphased" int nup = 0; for (i=0; iss + 4*i + nup; int up = 0, all; for (all=0; all < 2; all++){ // checking for premature ending if ( !ss[0] || !ss[1] || !ss[2] || (up && (!ss[3] || !ss[4]) ) ) { fprintf(stderr,"Wrong number of fields at %d-th sample ([%c][%c][%c]). ",i+1,ss[0],ss[1],ss[2]); return -1; } switch(ss[all*2+up]){ case '0': args->gts[2*i+all] = a0; break; case '1' : args->gts[2*i+all] = a1; break; case '?' : // there is no macro to express phased missing allele args->gts[2*i+all] = bcf_gt_phased(-1); break; case '-' : args->gts[2*i+all] = bcf_int32_vector_end; break; default : fprintf(stderr,"Could not parse: [%c][%s]\n", ss[all*2+up],tsv->ss); return -1; } if( ss[all*2+up+1]=='*' ) up = up + 1; } if(up && up != 2) { fprintf(stderr,"Missing unphased marker '*': [%c][%s]", ss[2+up], tsv->ss); return -1; } // change alleles to unphased if the alleles are unphased if ( up ) { args->gts[2*i] = bcf_gt_unphased(bcf_gt_allele(args->gts[2*i])); args->gts[2*i+1] = bcf_gt_unphased(bcf_gt_allele(args->gts[2*i+1])); } nup = nup + up; } if ( tsv->ss[(nsamples-1)*4+3+nup] ) { fprintf(stderr,"nup: %d", nup); fprintf(stderr,"Wrong number of fields (%d-th column = [%c]). ", nsamples*2,tsv->ss[(nsamples-1)*4+nup]); return -1; } if ( bcf_update_genotypes(args->header,rec,args->gts,nsamples*2) ) error("Could not update GT field\n"); return 0; } static void gensample_to_vcf(args_t *args) { /* * Inpute: IMPUTE2 output (indentation changed here for clarity): * * 20:62116619_C_T 20:62116619 62116619 C T 0.969 0.031 0 ... * --- 20:62116698_C_A 62116698 C A 1 0 0 ... * * Second column is expected in the form of CHROM:POS_REF_ALT. We use second * column because the first can be empty ("--") when filling sites from reference * panel. When the option --vcf-ids is given, the first column is used to set the * VCF ID. * * Output: VCF with filled GT,GP * */ kstring_t line = {0,0,0}; char *gen_fname = NULL, *sample_fname = NULL; sample_fname = strchr(args->infname,','); if ( !sample_fname ) { args->str.l = 0; ksprintf(&args->str,"%s.gen.gz", args->infname); gen_fname = strdup(args->str.s); args->str.l = 0; ksprintf(&args->str,"%s.samples", args->infname); sample_fname = strdup(args->str.s); } else { *sample_fname = 0; gen_fname = strdup(args->infname); sample_fname = strdup(sample_fname+1); } htsFile *gen_fh = hts_open(gen_fname, "r"); if ( !gen_fh ) error("Could not read: %s\n", gen_fname); if ( hts_getline(gen_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", gen_fname); // Find out the chromosome name, depending on the format variant (--3N6 or plain) and the ordering // of the columns (CHROM:POS_REF_ALT comes first or second) args->str.l = 0; char *sb = line.s, *se = line.s; while ( *se && !isspace(*se) ) se++; if ( !*se ) error("Could not determine CHROM in %s: %s\n", gen_fname,line.s); if ( args->gen_3N6 ) // first column, just CHROM kputsn(sb, se-sb, &args->str); else // first or second column, part of CHROM:POS_REF_ALT { char *sc = strchr(sb,':'); if ( !sc || sc > se ) { while ( *se && !isspace(*se) ) se++; if ( !*se ) error("Could not determine CHROM in %s: %s\n", gen_fname,line.s); sb = ++se; sc = strchr(sb,':'); if ( !sc ) error("Could not determine CHROM in %s: %s\n", gen_fname,line.s); } kputsn(sb, sc-sb, &args->str); } // Initialize and print the VCF header, args->str.s contains the chr name args->header = bcf_hdr_init("w"); bcf_hdr_append(args->header, "##INFO="); bcf_hdr_append(args->header, "##FORMAT="); bcf_hdr_append(args->header, "##FORMAT="); bcf_hdr_printf(args->header, "##contig=", args->str.s,0x7fffffff); // MAX_CSI_COOR if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); tsv_t *tsv; if ( args->gen_3N6 ) { tsv = tsv_init("CHROM,CHROM_POS_REF_ALT,ID,POS,REF_ALT,GT_GP"); tsv_register(tsv, "CHROM", tsv_setter_chrom, args->header); } else tsv = tsv_init("CHROM_POS_REF_ALT,ID,POS,REF_ALT,GT_GP"); tsv_register(tsv, "CHROM_POS_REF_ALT", tsv_setter_chrom_pos_ref_alt_or_id, args); tsv_register(tsv, "ID", tsv_setter_chrom_pos_ref_alt_id_or_die, args); tsv_register(tsv, "POS", tsv_setter_verify_pos, NULL); tsv_register(tsv, "REF_ALT", tsv_setter_verify_ref_alt, args); tsv_register(tsv, "GT_GP", tsv_setter_gt_gp, args); // Find out sample names int i, nsamples; char **samples = hts_readlist(sample_fname, 1, &nsamples); if ( !samples ) error("Could not read %s\n", sample_fname); for (i=2; iheader,samples[i]); } for (i=0; ioutput_type,args->outfname,args->clevel); htsFile *out_fh = hts_open(args->outfname ? args->outfname : "-", wmode); if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); if ( bcf_hdr_write(out_fh,args->header)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->outfname); if ( init_index2(out_fh,args->header,args->outfname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->outfname); bcf1_t *rec = bcf_init(); nsamples -= 2; args->gts = (int32_t *) malloc(sizeof(int32_t)*nsamples*2); args->flt = (float *) malloc(sizeof(float)*nsamples*3); do { bcf_clear(rec); args->n.total++; if ( !tsv_parse(tsv, rec, line.s) ) { if ( bcf_write(out_fh, args->header, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); } else error("Error occurred while parsing: %s\n", line.s); } while ( hts_getline(gen_fh, KS_SEP_LINE, &line)>0 ); if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); if ( hts_close(gen_fh) ) error("Close failed: %s\n", gen_fname); bcf_hdr_destroy(args->header); bcf_destroy(rec); free(sample_fname); free(gen_fname); free(args->str.s); free(line.s); free(args->gts); free(args->flt); tsv_destroy(tsv); fprintf(stderr,"Number of processed rows: \t%d\n", args->n.total); } static void haplegendsample_to_vcf(args_t *args) { /* * Convert from IMPUTE2 hap/legend/sample output files to VCF * * hap: * 0 1 0 1 * legend: * id position a0 a1 * 1:186946386_G_T 186946386 G T * sample: * sample population group sex * sample1 sample1 sample1 2 * sample2 sample2 sample2 2 * * Output: VCF with filled GT */ kstring_t line = {0,0,0}; if ( args->output_vcf_ids ) error( "The option --haplegendsample2vcf cannot be combined with --vcf-ids. This is because the\n" "ID column must be formatted as \"CHROM:POS_REF_ALT\" to check sanity of the operation\n"); char *hap_fname = NULL, *leg_fname = NULL, *sample_fname = NULL; sample_fname = strchr(args->infname,','); if ( !sample_fname ) { args->str.l = 0; ksprintf(&args->str,"%s.hap.gz", args->infname); hap_fname = strdup(args->str.s); args->str.l = 0; ksprintf(&args->str,"%s.samples", args->infname); sample_fname = strdup(args->str.s); args->str.l = 0; ksprintf(&args->str,"%s.legend.gz", args->infname); leg_fname = strdup(args->str.s); } else { char *ss = sample_fname, *se = strchr(ss+1,','); if ( !se ) error("Could not parse hap/legend/sample file names: %s\n", args->infname); *ss = 0; *se = 0; hap_fname = strdup(args->infname); leg_fname = strdup(ss+1); sample_fname = strdup(se+1); } htsFile *hap_fh = hts_open(hap_fname, "r"); if ( !hap_fh ) error("Could not read: %s\n", hap_fname); htsFile *leg_fh = hts_open(leg_fname,"r"); if ( !leg_fh ) error("Could not read: %s\n", leg_fname); // Eat up first legend line, then determine chromosome name if ( hts_getline(leg_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", leg_fname); if ( hts_getline(leg_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", leg_fname); // Find out the chromosome name, sample names, init and print the VCF header args->str.l = 0; char *se = strchr(line.s,':'); if ( !se ) error("Expected CHROM:POS_REF_ALT in first column of %s\n", leg_fname); kputsn(line.s, se-line.s, &args->str); tsv_t *leg_tsv = tsv_init("CHROM_POS_REF_ALT,POS,REF_ALT"); tsv_register(leg_tsv, "CHROM_POS_REF_ALT", tsv_setter_chrom_pos_ref_alt, args); tsv_register(leg_tsv, "POS", tsv_setter_verify_pos, NULL); tsv_register(leg_tsv, "REF_ALT", tsv_setter_verify_ref_alt, args); tsv_t *hap_tsv = tsv_init("HAPS"); tsv_register(hap_tsv, "HAPS", tsv_setter_haps, args); args->header = bcf_hdr_init("w"); bcf_hdr_append(args->header, "##INFO="); bcf_hdr_append(args->header, "##FORMAT="); bcf_hdr_printf(args->header, "##contig=", args->str.s,0x7fffffff); // MAX_CSI_COOR if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); int i, nrows, nsamples; char **samples = hts_readlist(sample_fname, 1, &nrows); if ( !samples ) error("Could not read %s\n", sample_fname); nsamples = nrows - 1; // sample_fname should contain a header line, so need to ignore first row // returned from hts_readlist (i=1, and not i=0) for (i=1; iheader,samples[i]); } bcf_hdr_add_sample(args->header,NULL); for (i=0; ioutput_type,args->outfname,args->clevel); htsFile *out_fh = hts_open(args->outfname ? args->outfname : "-", wmode); if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); if ( bcf_hdr_write(out_fh,args->header)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->outfname); if ( init_index2(out_fh,args->header,args->outfname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->outfname); bcf1_t *rec = bcf_init(); args->gts = (int32_t *) malloc(sizeof(int32_t)*nsamples*2); while (1) { bcf_clear(rec); args->n.total++; if ( tsv_parse(leg_tsv, rec, line.s) ) error("Error occurred while parsing %s: %s\n", leg_fname,line.s); if ( hts_getline(hap_fh, KS_SEP_LINE, &line)<=0 ) error("Different number of records in %s and %s?\n", leg_fname,hap_fname); if ( tsv_parse(hap_tsv, rec, line.s) ) error("Error occurred while parsing %s: %s\n", hap_fname,line.s); if ( bcf_write(out_fh, args->header, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); if ( hts_getline(leg_fh, KS_SEP_LINE, &line)<=0 ) { if ( hts_getline(hap_fh, KS_SEP_LINE, &line)>0 ) error("Different number of records in %s and %s?\n", leg_fname,hap_fname); break; } } if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); if ( hts_close(hap_fh) ) error("Close failed: %s\n", hap_fname); if ( hts_close(leg_fh) ) error("Close failed: %s\n", leg_fname); bcf_hdr_destroy(args->header); bcf_destroy(rec); free(sample_fname); free(hap_fname); free(leg_fname); free(args->str.s); free(line.s); free(args->gts); tsv_destroy(hap_tsv); tsv_destroy(leg_tsv); fprintf(stderr,"Number of processed rows: \t%d\n", args->n.total); } static void hapsample_to_vcf(args_t *args) { /* * Input: SHAPEIT output * * 20:19995888_A_G rsid1 19995888 A G 0 0 0 0 ... * 20 20:19995888_A_G 19995888 A G 0 0 0 0 ... * * First column is expected in the form of CHROM:POS_REF_ALT * * Output: VCF with filled GT * */ kstring_t line = {0,0,0}; char *hap_fname = NULL, *sample_fname = NULL; sample_fname = strchr(args->infname,','); if ( !sample_fname ) { args->str.l = 0; ksprintf(&args->str,"%s.hap.gz", args->infname); hap_fname = strdup(args->str.s); args->str.l = 0; ksprintf(&args->str,"%s.samples", args->infname); sample_fname = strdup(args->str.s); } else { *sample_fname = 0; hap_fname = strdup(args->infname); sample_fname = strdup(sample_fname+1); } htsFile *hap_fh = hts_open(hap_fname, "r"); if ( !hap_fh ) error("Could not read: %s\n", hap_fname); if ( hts_getline(hap_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", hap_fname); // Find out the chromosome name, it can be either in the first or second column args->str.l = 0; char *sb = line.s, *se = line.s; while ( *se && !isspace(*se) ) se++; if ( !*se ) error("Could not determine CHROM in %s: %s\n", hap_fname,line.s); if ( !args->output_vcf_ids ) { // first column should be just CHROM, but the second must be CHROM:POS_REF_ALT, use that sb = ++se; while ( *se && !isspace(*se) ) se++; if ( !*se ) error("Could not determine CHROM in %s: %s\n", hap_fname,line.s); if ( !strchr(sb,':') ) error("Could not determine CHROM in the second column of %s: %s\n", hap_fname,line.s); } // Parse CHROM:POS_REF_ALT char *sc = strchr(sb,':'); if ( !sc || sc > se ) error("Could not determine CHROM in %s: %s\n", hap_fname,line.s); kputsn(sb, sc-sb, &args->str); // Initialize and print the VCF header, args->str.s contains the chr name args->header = bcf_hdr_init("w"); bcf_hdr_append(args->header, "##INFO="); bcf_hdr_append(args->header, "##FORMAT="); bcf_hdr_printf(args->header, "##contig=", args->str.s,0x7fffffff); // MAX_CSI_COOR if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); tsv_t *tsv; if ( args->output_vcf_ids ) { tsv = tsv_init("CHROM_POS_REF_ALT,ID,POS,REF_ALT,HAPS"); tsv_register(tsv, "ID", tsv_setter_id, args); } else { tsv = tsv_init("CHROM,CHROM_POS_REF_ALT,POS,REF_ALT,HAPS"); tsv_register(tsv, "CHROM", tsv_setter_chrom_pos_ref_alt_or_chrom, args); } tsv_register(tsv, "CHROM_POS_REF_ALT", tsv_setter_chrom_pos_ref_alt, args); tsv_register(tsv, "POS", tsv_setter_verify_pos, NULL); tsv_register(tsv, "REF_ALT", tsv_setter_verify_ref_alt, args); tsv_register(tsv, "HAPS", tsv_setter_haps, args); int i, nsamples; char **samples = hts_readlist(sample_fname, 1, &nsamples); if ( !samples ) error("Could not read %s\n", sample_fname); for (i=2; iheader,samples[i]); } bcf_hdr_add_sample(args->header,NULL); for (i=0; ioutput_type,args->outfname,args->clevel); htsFile *out_fh = hts_open(args->outfname ? args->outfname : "-", wmode); if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); if ( bcf_hdr_write(out_fh,args->header)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); if ( init_index2(out_fh,args->header,args->outfname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->outfname); bcf1_t *rec = bcf_init(); nsamples -= 2; args->gts = (int32_t *) malloc(sizeof(int32_t)*nsamples*2); do { bcf_clear(rec); args->n.total++; if ( !tsv_parse(tsv, rec, line.s) ) { if ( bcf_write(out_fh, args->header, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); } else error("Error occurred while parsing: %s\n", line.s); } while ( hts_getline(hap_fh, KS_SEP_LINE, &line)>0 ); if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); if ( hts_close(hap_fh) ) error("Close failed: %s\n", hap_fname); bcf_hdr_destroy(args->header); bcf_destroy(rec); free(sample_fname); free(hap_fname); free(args->str.s); free(line.s); free(args->gts); tsv_destroy(tsv); fprintf(stderr,"Number of processed rows: \t%d\n", args->n.total); } char *init_sample2sex(bcf_hdr_t *hdr, char *sex_fname) { int i, nlines; char *sample2sex = (char*) calloc(bcf_hdr_nsamples(hdr),1); char **lines = hts_readlist(sex_fname, 1, &nlines); if ( !lines ) error("Could not read %s\n", sex_fname); for (i=0; igen_3N6 ) kputs("%CHROM ", &str); kputs("%CHROM:%POS\\_%REF\\_%FIRST_ALT ", &str); // insert rsid as second column if needed if ( args->output_vcf_ids ) kputs("%ID ", &str); else kputs("%CHROM:%POS\\_%REF\\_%FIRST_ALT ", &str); kputs("%POS %REF %FIRST_ALT", &str); if ( !args->tag || !strcmp(args->tag,"GT") ) kputs("%_GT_TO_PROB3",&str); else if ( !strcmp(args->tag,"PL") ) kputs("%_PL_TO_PROB3",&str); else if ( !strcmp(args->tag,"GP") ) kputs("%_GP_TO_PROB3",&str); else error("todo: --tag %s\n", args->tag); kputs("\n", &str); open_vcf(args,str.s); int ret, gen_compressed = 1, sample_compressed = 0; char *gen_fname = NULL, *sample_fname = NULL; str.l = 0; kputs(args->outfname,&str); int n_files = 0, i; char **files = hts_readlist(str.s, 0, &n_files); if ( n_files==1 ) { int l = str.l; kputs(".samples",&str); sample_fname = strdup(str.s); str.l = l; kputs(".gen.gz",&str); gen_fname = strdup(str.s); } else if ( n_files==2 ) { if (strlen(files[0]) && strcmp(files[0],".")!=0) gen_fname = strdup(files[0]); if (strlen(files[1]) && strcmp(files[1],".")!=0) sample_fname = strdup(files[1]); } else { error("Error parsing --gensample filenames: %s\n", args->outfname); } for (i=0; i3 && strcasecmp(".gz",sample_fname+strlen(sample_fname)-3)==0 ) sample_compressed = 0; if (gen_fname) fprintf(stderr, "Gen file: %s\n", gen_fname); if (sample_fname) fprintf(stderr, "Sample file: %s\n", sample_fname); // write samples file if (sample_fname) { char *sample2sex = NULL; if ( args->sex_fname ) sample2sex = init_sample2sex(args->header,args->sex_fname); int i; BGZF *sout = bgzf_open(sample_fname, sample_compressed ? "wg" : "wu"); str.l = 0; kputs(sample2sex ? "ID_1 ID_2 missing sex\n0 0 0 0\n" : "ID_1 ID_2 missing\n0 0 0\n", &str); ret = bgzf_write(sout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); for (i=0; iheader); i++) { str.l = 0; if ( sample2sex ) ksprintf(&str, "%s %s 0 %c\n", args->header->samples[i],args->header->samples[i],sample2sex[i]); else ksprintf(&str, "%s %s 0\n", args->header->samples[i],args->header->samples[i]); ret = bgzf_write(sout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); } if ( bgzf_close(sout)!=0 ) error("Error closing %s: %s\n", sample_fname, strerror(errno)); free(sample_fname); free(sample2sex); } if (!gen_fname) { if ( str.m ) free(str.s); return; } int prev_rid = -1, prev_pos = -1; int no_alt = 0, non_biallelic = 0, filtered = 0, ndup = 0, nok = 0; BGZF *gout = bgzf_open(gen_fname, gen_compressed ? "wg" : "wu"); while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { filtered++; continue; } } // ALT allele is required if ( line->n_allele<2 ) { no_alt++; continue; } // biallelic required if ( line->n_allele>2 ) { if (!non_biallelic) fprintf(stderr, "Warning: non-biallelic records are skipped. Consider splitting multi-allelic records into biallelic records using 'bcftools norm -m-'.\n"); non_biallelic++; continue; } // skip duplicate lines, or otherwise shapeit complains if ( !args->keep_duplicates && prev_rid==line->rid && prev_pos==line->pos ) { ndup++; continue; } prev_rid = line->rid; prev_pos = line->pos; str.l = 0; convert_line(args->convert, line, &str); if ( str.l ) { int ret = bgzf_write(gout, str.s, str.l); if ( ret!= str.l ) error("Error writing %s: %s\n", gen_fname,strerror(errno)); nok++; } } fprintf(stderr, "%d records written, %d skipped: %d/%d/%d/%d no-ALT/non-biallelic/filtered/duplicated\n", nok, no_alt+non_biallelic+filtered+ndup, no_alt, non_biallelic, filtered, ndup); if ( str.m ) free(str.s); if ( bgzf_close(gout)!=0 ) error("Error closing %s: %s\n", gen_fname,strerror(errno)); free(gen_fname); } static void vcf_to_haplegendsample(args_t *args) { kstring_t str = {0,0,0}; if ( args->hap2dip ) kputs("%_GT_TO_HAP2\n", &str); else kputs("%_GT_TO_HAP\n", &str); open_vcf(args,str.s); int ret, hap_compressed = 1, legend_compressed = 1, sample_compressed = 0; char *hap_fname = NULL, *legend_fname = NULL, *sample_fname = NULL; str.l = 0; kputs(args->outfname,&str); int n_files = 0, i; char **files = hts_readlist(str.s, 0, &n_files); if ( n_files==1 ) { int l = str.l; kputs(".samples",&str); sample_fname = strdup(str.s); str.l = l; kputs(".legend.gz",&str); legend_fname = strdup(str.s); str.l = l; kputs(".hap.gz",&str); hap_fname = strdup(str.s); } else if ( n_files==3 ) { if (strlen(files[0]) && strcmp(files[0],".")!=0) hap_fname = strdup(files[0]); if (strlen(files[1]) && strcmp(files[1],".")!=0) legend_fname = strdup(files[1]); if (strlen(files[2]) && strcmp(files[2],".")!=0) sample_fname = strdup(files[2]); } else { error("Error parsing --hapslegendsample filenames: %s\n", args->outfname); } for (i=0; i3 && strcasecmp(".gz",sample_fname+strlen(sample_fname)-3)==0 ) sample_compressed = 0; if (hap_fname) fprintf(stderr, "Hap file: %s\n", hap_fname); if (legend_fname) fprintf(stderr, "Legend file: %s\n", legend_fname); if (sample_fname) fprintf(stderr, "Sample file: %s\n", sample_fname); // write samples file if (sample_fname) { char *sample2sex = NULL; if ( args->sex_fname ) sample2sex = init_sample2sex(args->header,args->sex_fname); int i; BGZF *sout = bgzf_open(sample_fname, sample_compressed ? "wg" : "wu"); str.l = 0; kputs("sample population group sex\n", &str); ret = bgzf_write(sout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); for (i=0; iheader); i++) { str.l = 0; ksprintf(&str, "%s %s %s %c\n", args->header->samples[i], args->header->samples[i], args->header->samples[i], sample2sex ? sample2sex[i] : '2'); ret = bgzf_write(sout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); } if ( bgzf_close(sout)!=0 ) error("Error closing %s: %s\n", sample_fname, strerror(errno)); free(sample_fname); free(sample2sex); } if (!hap_fname && !legend_fname) { if ( str.m ) free(str.s); return; } // open haps and legend outputs BGZF *hout = hap_fname ? bgzf_open(hap_fname, hap_compressed ? "wg" : "wu") : NULL; if ( hap_compressed && args->n_threads ) bgzf_thread_pool(hout, args->files->p->pool, args->files->p->qsize); BGZF *lout = legend_fname ? bgzf_open(legend_fname, legend_compressed ? "wg" : "wu") : NULL; if (legend_fname) { str.l = 0; kputs("id position a0 a1\n", &str); ret = bgzf_write(lout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", legend_fname, strerror(errno)); } int no_alt = 0, non_biallelic = 0, filtered = 0, nok = 0; while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { filtered++; continue; } } // ALT allele is required if ( line->n_allele<2 ) { no_alt++; continue; } // biallelic required if ( line->n_allele>2 ) { if (!non_biallelic) fprintf(stderr, "Warning: non-biallelic records are skipped. Consider splitting multi-allelic records into biallelic records using 'bcftools norm -m-'.\n"); non_biallelic++; continue; } str.l = 0; convert_line(args->convert, line, &str); if ( !str.l ) continue; // write haps file if (hap_fname) { ret = bgzf_write(hout, str.s, str.l); // write hap file if ( ret != str.l ) error("Error writing %s: %s\n", hap_fname, strerror(errno)); } if (legend_fname) { str.l = 0; if ( args->output_vcf_ids && (line->d.id[0]!='.' || line->d.id[1]!=0) ) ksprintf(&str, "%s %"PRId64" %s %s\n", line->d.id, (int64_t) line->pos+1, line->d.allele[0], line->d.allele[1]); else ksprintf(&str, "%s:%"PRId64"_%s_%s %"PRId64" %s %s\n", bcf_seqname(args->header, line), (int64_t) line->pos+1, line->d.allele[0], line->d.allele[1], (int64_t) line->pos+1, line->d.allele[0], line->d.allele[1]); // write legend file ret = bgzf_write(lout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", legend_fname, strerror(errno)); } nok++; } fprintf(stderr, "%d records written, %d skipped: %d/%d/%d no-ALT/non-biallelic/filtered\n", nok,no_alt+non_biallelic+filtered, no_alt, non_biallelic, filtered); if ( str.m ) free(str.s); if ( hout && bgzf_close(hout)!=0 ) error("Error closing %s: %s\n", hap_fname, strerror(errno)); if ( lout && bgzf_close(lout)!=0 ) error("Error closing %s: %s\n", legend_fname, strerror(errno)); if (hap_fname) free(hap_fname); if (legend_fname) free(legend_fname); } static void vcf_to_hapsample(args_t *args) { /* * WTCCC style haplotypes file * see https://mathgen.stats.ox.ac.uk/genetics_software/shapeit/shapeit.html#hapsample * * These are essentially the haplotypes from the impute2 format with some * legend info tacked on to the first 5 columns * */ kstring_t str = {0,0,0}; // print ID instead of CHROM:POS_REF_ALT1 if ( args->output_vcf_ids ) kputs("%CHROM:%POS\\_%REF\\_%FIRST_ALT %ID %POS %REF %FIRST_ALT ", &str); else kputs("%CHROM %CHROM:%POS\\_%REF\\_%FIRST_ALT %POS %REF %FIRST_ALT ", &str); if ( args->hap2dip ) kputs("%_GT_TO_HAP2\n", &str); else kputs("%_GT_TO_HAP\n", &str); open_vcf(args,str.s); int ret, hap_compressed = 1, sample_compressed = 0; char *hap_fname = NULL, *sample_fname = NULL; str.l = 0; kputs(args->outfname,&str); int n_files = 0, i; char **files = hts_readlist(str.s, 0, &n_files); if ( n_files==1 ) { int l = str.l; kputs(".samples",&str); sample_fname = strdup(str.s); str.l = l; kputs(".hap.gz",&str); hap_fname = strdup(str.s); } else if ( n_files==2 ) { if (strlen(files[0]) && strcmp(files[0],".")!=0) hap_fname = strdup(files[0]); if (strlen(files[1]) && strcmp(files[1],".")!=0) sample_fname = strdup(files[1]); } else { error("Error parsing --hapsample filenames: %s\n", args->outfname); } for (i=0; i3 && strcasecmp(".gz",sample_fname+strlen(sample_fname)-3)==0 ) sample_compressed = 0; if (hap_fname) fprintf(stderr, "Hap file: %s\n", hap_fname); if (sample_fname) fprintf(stderr, "Sample file: %s\n", sample_fname); // write samples file if (sample_fname) { char *sample2sex = NULL; if ( args->sex_fname ) sample2sex = init_sample2sex(args->header,args->sex_fname); int i; BGZF *sout = bgzf_open(sample_fname, sample_compressed ? "wg" : "wu"); str.l = 0; kputs(sample2sex ? "ID_1 ID_2 missing sex\n0 0 0 0\n" : "ID_1 ID_2 missing\n0 0 0\n", &str); ret = bgzf_write(sout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); for (i=0; iheader); i++) { str.l = 0; if ( sample2sex ) ksprintf(&str, "%s %s 0 %c\n", args->header->samples[i],args->header->samples[i],sample2sex[i]); else ksprintf(&str, "%s %s 0\n", args->header->samples[i],args->header->samples[i]); ret = bgzf_write(sout, str.s, str.l); if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); } if ( bgzf_close(sout)!=0 ) error("Error closing %s: %s\n", sample_fname, strerror(errno)); free(sample_fname); free(sample2sex); } if (!hap_fname) { if ( str.m ) free(str.s); return; } // open haps output BGZF *hout = hap_fname ? bgzf_open(hap_fname, hap_compressed ? "wg" : "wu") : NULL; if ( hap_compressed && args->n_threads ) bgzf_thread_pool(hout, args->files->p->pool, args->files->p->qsize); int no_alt = 0, non_biallelic = 0, filtered = 0, nok = 0; while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { filtered++; continue; } } // ALT allele is required if ( line->n_allele<2 ) { no_alt++; continue; } // biallelic required if ( line->n_allele>2 ) { if (!non_biallelic) fprintf(stderr, "Warning: non-biallelic records are skipped. Consider splitting multi-allelic records into biallelic records using 'bcftools norm -m-'.\n"); non_biallelic++; continue; } str.l = 0; convert_line(args->convert, line, &str); if ( !str.l ) continue; // write haps file if (hap_fname) { ret = bgzf_write(hout, str.s, str.l); // write hap file if ( ret != str.l ) error("Error writing %s: %s\n", hap_fname, strerror(errno)); } nok++; } fprintf(stderr, "%d records written, %d skipped: %d/%d/%d no-ALT/non-biallelic/filtered\n", nok, no_alt+non_biallelic+filtered, no_alt, non_biallelic, filtered); if ( str.m ) free(str.s); if ( hout && bgzf_close(hout)!=0 ) error("Error closing %s: %s\n", hap_fname, strerror(errno)); if (hap_fname) free(hap_fname); } static void bcf_hdr_set_chrs(bcf_hdr_t *hdr, faidx_t *fai) { int i, n = faidx_nseq(fai); for (i=0; i", seq,len); } } static inline int acgt_to_5(char base) { if ( base=='A' ) return 0; if ( base=='C' ) return 1; if ( base=='G' ) return 2; if ( base=='T' ) return 3; return 4; } static inline int tsv_setter_aa1(args_t *args, char *ss, char *se, int alleles[], int *nals, int ref, int32_t *gts) { if ( se - ss > 2 ) return -1; // currently only SNPs if ( ss[0]=='-' || ss[0]=='.' ) { // missing GT gts[0] = bcf_gt_missing; gts[1] = bcf_gt_missing; args->n.missing++; return 0; } if ( ss[0]=='I' ) return -2; // skip insertions/deletions for now if ( ss[0]=='D' ) return -2; int a0 = acgt_to_5(toupper(ss[0])); int a1 = ss[1] ? acgt_to_5(toupper(ss[1])) : a0; if ( alleles[a0]<0 ) alleles[a0] = (*nals)++; if ( alleles[a1]<0 ) alleles[a1] = (*nals)++; gts[0] = bcf_gt_unphased(alleles[a0]); gts[1] = ss[1] ? bcf_gt_unphased(alleles[a1]) : bcf_int32_vector_end; if ( ref==a0 && ref==a1 ) args->n.hom_rr++; // hom ref: RR else if ( ref==a0 ) args->n.het_ra++; // het: RA else if ( ref==a1 ) args->n.het_ra++; // het: AR else if ( a0==a1 ) args->n.hom_aa++; // hom-alt: AA else args->n.het_aa++; // non-ref het: AA return 0; } static int tsv_setter_aa(tsv_t *tsv, bcf1_t *rec, void *usr) { args_t *args = (args_t*) usr; int len; char *ref = faidx_fetch_seq(args->ref, (char*)bcf_hdr_id2name(args->header,rec->rid), rec->pos, rec->pos, &len); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", bcf_hdr_id2name(args->header,rec->rid),(int64_t) rec->pos+1); int nals = 1, alleles[5] = { -1, -1, -1, -1, -1 }; // a,c,g,t,n ref[0] = toupper(ref[0]); int iref = acgt_to_5(ref[0]); alleles[iref] = 0; rec->n_sample = bcf_hdr_nsamples(args->header); int i, ret; for (i=0; in_sample; i++) { if ( i>0 ) { ret = tsv_next(tsv); if ( ret==-1 ) error("Too few columns for %d samples at %s:%"PRId64"\n", rec->n_sample,bcf_hdr_id2name(args->header,rec->rid),(int64_t) rec->pos+1); } ret = tsv_setter_aa1(args, tsv->ss, tsv->se, alleles, &nals, iref, args->gts+i*2); if ( ret==-1 ) error("Error parsing the site %s:%"PRId64", expected two characters\n", bcf_hdr_id2name(args->header,rec->rid),(int64_t) rec->pos+1); if ( ret==-2 ) { // something else than a SNP free(ref); return -1; } } args->str.l = 0; kputc(ref[0], &args->str); for (i=0; i<5; i++) { if ( alleles[i]>0 ) { kputc(',', &args->str); kputc("ACGTN"[i], &args->str); } } bcf_update_alleles_str(args->header, rec, args->str.s); if ( bcf_update_genotypes(args->header,rec,args->gts,rec->n_sample*2) ) error("Could not update the GT field\n"); free(ref); return 0; } static void tsv_to_vcf(args_t *args) { if ( !args->ref_fname ) error("--tsv2vcf requires the --fasta-ref option\n"); args->ref = fai_load(args->ref_fname); if ( !args->ref ) error("Could not load the reference %s\n", args->ref_fname); args->header = bcf_hdr_init("w"); bcf_hdr_set_chrs(args->header, args->ref); bcf_hdr_append(args->header, "##FORMAT="); if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); int i, nsmpl; char **smpl; if ( args->sample_list ) { smpl = hts_readlist(args->sample_list, args->sample_is_file, &nsmpl); if ( !smpl ) error("Could not parse %s\n", args->sample_list); for (i=0; iheader, smpl[i]); free(smpl[i]); } free(smpl); bcf_hdr_add_sample(args->header, NULL); args->gts = (int32_t *) malloc(sizeof(int32_t)*nsmpl*2); } char wmode[8]; set_wmode(wmode,args->output_type,args->outfname,args->clevel); htsFile *out_fh = hts_open(args->outfname ? args->outfname : "-", wmode); if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); if ( bcf_hdr_write(out_fh,args->header)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); if ( init_index2(out_fh,args->header,args->outfname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->outfname); tsv_t *tsv = tsv_init(args->columns ? args->columns : "ID,CHROM,POS,AA"); if ( tsv_register(tsv, "CHROM", tsv_setter_chrom, args->header) < 0 ) error("Expected CHROM column\n"); if ( tsv_register(tsv, "POS", tsv_setter_pos, NULL) < 0 ) error("Expected POS column\n"); if ( tsv_register(tsv, "ID", tsv_setter_id, args->header) < 0 && !args->columns ) error("Expected ID column\n"); if ( tsv_register(tsv, "AA", tsv_setter_aa, args) < 0 ) { if ( args->sample_list ) error("Expected AA column with -s/-S\n"); if ( tsv_register(tsv, "REF", tsv_setter_ref, args) < 0 || tsv_register(tsv, "ALT", tsv_setter_alt, args) < 0 ) error("Expected REF and ALT columns when AA was not given\n"); } bcf1_t *rec = bcf_init(); bcf_float_set_missing(rec->qual); kstring_t line = {0,0,0}; htsFile *in_fh = hts_open(args->infname, "r"); if ( !in_fh ) error("Could not read: %s\n", args->infname); while ( hts_getline(in_fh, KS_SEP_LINE, &line) > 0 ) { if ( line.s[0]=='#' ) continue; // skip comments bcf_clear(rec); args->n.total++; if ( !tsv_parse(tsv, rec, line.s) ) { if ( bcf_write(out_fh, args->header, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); args->n.written++; } else args->n.skipped++; } if ( hts_close(in_fh) ) error("Close failed: %s\n", args->infname); free(line.s); if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } bcf_hdr_destroy(args->header); if ( hts_close(out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->outfname); tsv_destroy(tsv); bcf_destroy(rec); free(args->str.s); free(args->gts); free(args->tsv.ref.s); free(args->tsv.alt.s); free(args->tsv.refalt.s); fprintf(stderr,"Rows total: \t%d\n", args->n.total); fprintf(stderr,"Rows skipped: \t%d\n", args->n.skipped); fprintf(stderr,"Sites written: \t%d\n", args->n.written); if ( args->sample_list ) { fprintf(stderr,"Missing GTs: \t%d\n", args->n.missing); fprintf(stderr,"Hom RR: \t%d\n", args->n.hom_rr); fprintf(stderr,"Het RA: \t%d\n", args->n.het_ra); fprintf(stderr,"Hom AA: \t%d\n", args->n.hom_aa); fprintf(stderr,"Het AA: \t%d\n", args->n.het_aa); } } static void vcf_to_vcf(args_t *args) { open_vcf(args,NULL); char wmode[8]; set_wmode(wmode,args->output_type,args->outfname,args->clevel); htsFile *out_fh = hts_open(args->outfname ? args->outfname : "-", wmode); if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); bcf_hdr_t *hdr = bcf_sr_get_header(args->files,0); if ( bcf_hdr_write(out_fh,hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); if ( init_index2(out_fh,args->header,args->outfname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->outfname); while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) continue; } if ( bcf_write(out_fh,hdr,line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); } if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->outfname); } static void gvcf_to_vcf(args_t *args) { if ( !args->ref_fname ) error("--gvcf2vcf requires the --fasta-ref option\n"); args->ref = fai_load(args->ref_fname); if ( !args->ref ) error("Could not load the fai index for reference %s\n", args->ref_fname); open_vcf(args,NULL); char wmode[8]; set_wmode(wmode,args->output_type,args->outfname,args->clevel); htsFile *out_fh = hts_open(args->outfname ? args->outfname : "-", wmode); if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); bcf_hdr_t *hdr = bcf_sr_get_header(args->files,0); if (args->record_cmd_line) bcf_hdr_append_version(hdr, args->argc, args->argv, "bcftools_convert"); if ( bcf_hdr_write(out_fh,hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); if ( init_index2(out_fh,hdr,args->outfname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->outfname); int32_t *itmp = NULL, nitmp = 0; while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { if ( bcf_write(out_fh,hdr,line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); continue; } } // check if alleles compatible with being a gVCF record // ALT must be one of ., <*>, , // check for INFO/END is below int i, gallele = -1; if (line->n_allele==1) gallele = 0; // illumina/bcftools-call gvcf (if INFO/END present) else if ( line->d.allele[1][0]=='<' ) { for (i=1; in_allele; i++) { if ( line->d.allele[i][1]=='*' && line->d.allele[i][2]=='>' && line->d.allele[i][3]=='\0' ) { gallele = i; break; } // mpileup/spec compliant gVCF if ( line->d.allele[i][1]=='X' && line->d.allele[i][2]=='>' && line->d.allele[i][3]=='\0' ) { gallele = i; break; } // old mpileup gVCF if ( strcmp(line->d.allele[i],"")==0 ) { gallele = i; break; } // GATK gVCF } } // no gVCF compatible alleles if (gallele<0) { if ( bcf_write(out_fh,hdr,line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); continue; } int nend = bcf_get_info_int32(hdr,line,"END",&itmp,&nitmp); if ( nend!=1 ) { // No INFO/END => not gVCF record if ( bcf_write(out_fh,hdr,line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); continue; } bcf_update_info_int32(hdr,line,"END",NULL,0); int pos, len; for (pos=line->pos; pospos = pos; char *ref = faidx_fetch_seq(args->ref, (char*)bcf_hdr_id2name(hdr,line->rid), line->pos, line->pos, &len); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", bcf_hdr_id2name(hdr,line->rid),(int64_t) line->pos+1); strncpy(line->d.allele[0],ref,len); if ( bcf_write(out_fh,hdr,line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->outfname); free(ref); } } free(itmp); if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->outfname); } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Converts VCF/BCF to other formats and back. See man page for file\n"); fprintf(stderr, " formats details. When specifying output files explicitly instead\n"); fprintf(stderr, " of with PREFIX, one can use '-' for stdout and '.' to suppress.\n"); fprintf(stderr, "Usage: bcftools convert [OPTIONS] INPUT_FILE\n"); fprintf(stderr, "\n"); fprintf(stderr, "VCF input options:\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true\n"); fprintf(stderr, " -i, --include EXPR Select sites for which the expression is true\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples LIST List of samples to include\n"); fprintf(stderr, " -S, --samples-file FILE File of samples to include\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, "\n"); fprintf(stderr, "VCF output options:\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Output file name [stdout]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " --threads INT Use multithreading with INT worker threads [0]\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); fprintf(stderr, "GEN/SAMPLE conversion (input/output from IMPUTE2):\n"); fprintf(stderr, " -G, --gensample2vcf ... |,\n"); fprintf(stderr, " -g, --gensample ... |,\n"); fprintf(stderr, " --3N6 Use 3*N+6 column format instead of the old 3*N+5 column format\n"); fprintf(stderr, " --tag STRING Tag to take values for .gen file: GT,PL,GL,GP [GT]\n"); fprintf(stderr, " --chrom Output chromosome in first column instead of CHROM:POS_REF_ALT\n"); fprintf(stderr, " --keep-duplicates Keep duplicate positions\n"); fprintf(stderr, " --sex FILE Output sex column in the sample-file, input format is: Sample\\t[MF]\n"); fprintf(stderr, " --vcf-ids Output VCF IDs in second column instead of CHROM:POS_REF_ALT\n"); fprintf(stderr, "\n"); fprintf(stderr, "gVCF conversion:\n"); fprintf(stderr, " --gvcf2vcf Expand gVCF reference blocks\n"); fprintf(stderr, " -f, --fasta-ref FILE Reference sequence in fasta format\n"); fprintf(stderr, "\n"); fprintf(stderr, "HAP/SAMPLE conversion (output from SHAPEIT):\n"); fprintf(stderr, " --hapsample2vcf ... |,\n"); fprintf(stderr, " --hapsample ... |,\n"); fprintf(stderr, " --haploid2diploid Convert haploid genotypes to diploid homozygotes\n"); fprintf(stderr, " --sex FILE Output sex column in the sample-file, input format is: Sample\\t[MF]\n"); fprintf(stderr, " --vcf-ids Output VCF IDs instead of CHROM:POS_REF_ALT\n"); fprintf(stderr, "\n"); fprintf(stderr, "HAP/LEGEND/SAMPLE conversion:\n"); fprintf(stderr, " -H, --haplegendsample2vcf ... |,,\n"); fprintf(stderr, " -h, --haplegendsample ... |,,\n"); fprintf(stderr, " --haploid2diploid Convert haploid genotypes to diploid homozygotes\n"); fprintf(stderr, " --sex FILE Output sex column in the sample-file, input format is: Sample\\t[MF]\n"); fprintf(stderr, " --vcf-ids Output VCF IDs instead of CHROM:POS_REF_ALT\n"); fprintf(stderr, "\n"); fprintf(stderr, "TSV conversion:\n"); fprintf(stderr, " --tsv2vcf FILE\n"); fprintf(stderr, " -c, --columns STRING Columns of the input tsv file, see man page for details [ID,CHROM,POS,AA]\n"); fprintf(stderr, " -f, --fasta-ref FILE Reference sequence in fasta format\n"); fprintf(stderr, " -s, --samples LIST List of sample names\n"); fprintf(stderr, " -S, --samples-file FILE File of sample names\n"); fprintf(stderr, "\n"); // fprintf(stderr, "PLINK options:\n"); // fprintf(stderr, " -p, --plink |,,|,,|,\n"); // fprintf(stderr, " --tped make tped file instead\n"); // fprintf(stderr, " --bin make binary bed/fam/bim files\n"); // fprintf(stderr, "\n"); // fprintf(stderr, "PBWT options:\n"); // fprintf(stderr, " -b, --pbwt or ,,,\n"); // fprintf(stderr, "\n"); exit(1); } int main_vcfconvert(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->outfname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->regions_overlap = 1; args->targets_overlap = 0; args->clevel = -1; static struct option loptions[] = { {"include",required_argument,NULL,'i'}, {"exclude",required_argument,NULL,'e'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,13}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,14}, {"samples",required_argument,NULL,'s'}, {"samples-file",required_argument,NULL,'S'}, {"sex",required_argument,NULL,11}, {"gensample",required_argument,NULL,'g'}, {"gensample2vcf",required_argument,NULL,'G'}, {"tag",required_argument,NULL,1}, {"chrom",no_argument,NULL,8}, {"3N6",no_argument,NULL,15}, {"tsv2vcf",required_argument,NULL,2}, {"hapsample",required_argument,NULL,7}, {"hapsample2vcf",required_argument,NULL,3}, {"vcf-ids",no_argument,NULL,4}, {"haploid2diploid",no_argument,NULL,5}, {"gvcf2vcf",no_argument,NULL,6}, {"haplegendsample",required_argument,NULL,'h'}, {"haplegendsample2vcf",required_argument,NULL,'H'}, {"columns",required_argument,NULL,'c'}, {"fasta-ref",required_argument,NULL,'f'}, {"no-version",no_argument,NULL,10}, {"keep-duplicates",no_argument,NULL,12}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "?h:r:R:s:S:t:T:i:e:g:G:o:O:c:f:H:W::",loptions,NULL)) >= 0) { switch (c) { case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; args->targets_is_file = 1; break; case 's': args->sample_list = optarg; break; case 'S': args->sample_list = optarg; args->sample_is_file = 1; break; case 'g': args->convert_func = vcf_to_gensample; args->outfname = optarg; break; case 'G': args->convert_func = gensample_to_vcf; args->infname = optarg; break; case 1 : args->tag = optarg; break; case 2 : args->convert_func = tsv_to_vcf; args->infname = optarg; break; case 3 : args->convert_func = hapsample_to_vcf; args->infname = optarg; break; case 4 : args->output_vcf_ids = 1; break; case 5 : args->hap2dip = 1; break; case 6 : args->convert_func = gvcf_to_vcf; break; case 7 : args->convert_func = vcf_to_hapsample; args->outfname = optarg; break; case 8 : error("The --chrom option has been deprecated, please use --3N6 instead\n"); break; case 15 : args->gen_3N6 = 1; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'H': args->convert_func = haplegendsample_to_vcf; args->infname = optarg; break; case 'f': args->ref_fname = optarg; break; case 'c': args->columns = optarg; break; case 'o': args->outfname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'h': args->convert_func = vcf_to_haplegendsample; args->outfname = optarg; break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 10 : args->record_cmd_line = 0; break; case 11 : args->sex_fname = optarg; break; case 12 : args->keep_duplicates = 1; break; case 13 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 14 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } if ( !args->infname ) { if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->infname = "-"; } else args->infname = argv[optind]; } if ( !args->infname ) usage(); if ( args->convert_func ) args->convert_func(args); else vcf_to_vcf(args); destroy_data(args); free(args); return 0; } bcftools-1.21/vcffilter.c000066400000000000000000000754651467060157400154330ustar00rootroot00000000000000/* vcffilter.c -- Apply fixed-threshold filters. Copyright (C) 2013-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "rbuf.h" #include "regidx.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 // FILTER columns annotation: replace or add to existing FILTERs; set FILTER to PASS at good sites? #define ANNOT_ADD 1 #define ANNOT_RESET 2 // Set genotypes of filtered samples #define SET_GTS_MISSING 1 #define SET_GTS_REF 2 typedef struct _args_t { filter_t *filter; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE const uint8_t *smpl_pass; int set_gts; char *soft_filter; // drop failed sites or annotate FILTER column? int annot_mode; // add to existing FILTER annotation or replace? Otherwise reset FILTER to PASS or leave as it is? int flt_fail, flt_pass; // BCF ids of fail and pass filters int snp_gap, snp_gap_type, indel_gap, IndelGap_id, SnpGap_id; char *snp_gap_str; int32_t ntmpi, *tmpi, ntmp_ac, *tmp_ac; rbuf_t rbuf; bcf1_t **rbuf_lines; bcf_srs_t *files; bcf_hdr_t *hdr; htsFile *out_fh; int output_type, n_threads, clevel; char **argv, *output_fname, *targets_list, *regions_list, *mask_list; int argc, record_cmd_line, mask_is_file, mask_overlap, mask_negate; regidx_t *mask; char *index_fn; int write_index; } args_t; static void init_data(args_t *args) { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); if ( args->mask_list ) { if ( args->mask_list[0]=='^' ) args->mask_negate = 1; if ( args->mask_is_file ) args->mask = regidx_init(args->mask_negate?args->mask_list+1:args->mask_list,NULL,NULL,0,NULL); else { char *rmme = strdup(args->mask_negate?args->mask_list+1:args->mask_list), *tmp = rmme; while ( *tmp ) { if ( *tmp==',' ) *tmp = '\n'; tmp++; } args->mask = regidx_init_string(rmme, regidx_parse_reg, NULL, 0, NULL); free(rmme); } if ( !args->mask ) error("Could not initialize the mask: %s\n",args->mask_list); } args->hdr = args->files->readers[0].header; args->flt_pass = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"PASS"); assert( !args->flt_pass ); // sanity check: required by BCF spec if ( args->soft_filter && (args->filter_logic || args->mask_list) ) { kstring_t flt_name = {0,0,0}; if ( strcmp(args->soft_filter,"+") ) kputs(args->soft_filter, &flt_name); else { // Make up a filter name int i = 0, id = -1; do { ksprintf(&flt_name,"Filter%d", ++i); id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,flt_name.s); } while ( bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FLT,id) ); } kstring_t tmp = {0,0,0}; if ( args->filter_logic ) { // -i or -e: append FILTER line ksprintf(&tmp,"Set if %s: ",args->filter_logic & FLT_INCLUDE ? "not true" : "true"); // escape quotes char *t = args->filter_str; while ( *t ) { if ( *t=='"' ) kputc('\\',&tmp); kputc(*t,&tmp); t++; } } else if ( args->mask_list ) ksprintf(&tmp,"Record masked by region"); int ret = bcf_hdr_printf(args->hdr, "##FILTER=", flt_name.s,tmp.s); if ( ret!=0 ) error("Failed to append header line: ##FILTER=\n", flt_name.s,tmp.s); args->flt_fail = bcf_hdr_id2int(args->hdr,BCF_DT_ID,flt_name.s); assert( args->flt_fail>=0 ); free(flt_name.s); free(tmp.s); } if ( args->snp_gap || args->indel_gap ) { if ( !args->filter_logic && args->soft_filter && strcmp(args->soft_filter,"+") ) { kstring_t tmp = {0,0,0}; if ( args->snp_gap ) kputs("\"SnpGap\"", &tmp); if ( args->indel_gap ) { if ( tmp.s ) kputs(" and ", &tmp); kputs("\"IndelGap\"", &tmp); } if ( strncmp(tmp.s+1,args->soft_filter,tmp.l-2) ) fprintf(stderr,"Warning: using %s filter name instead of \"%s\"\n", tmp.s,args->soft_filter); free(tmp.s); } rbuf_init(&args->rbuf, 64); args->rbuf_lines = (bcf1_t**) calloc(args->rbuf.m, sizeof(bcf1_t*)); if ( args->snp_gap ) { bcf_hdr_printf(args->hdr, "##FILTER=", args->snp_gap,args->snp_gap_str); args->SnpGap_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "SnpGap"); assert( args->SnpGap_id>=0 ); } if ( args->indel_gap ) { bcf_hdr_printf(args->hdr, "##FILTER=", args->indel_gap); args->IndelGap_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "IndelGap"); assert( args->IndelGap_id>=0 ); } } if (args->record_cmd_line) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_filter"); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); } static void destroy_data(args_t *args) { if ( args->rbuf_lines ) { int i; for (i=0; irbuf.m; i++) if ( args->rbuf_lines[i] ) bcf_destroy1(args->rbuf_lines[i]); free(args->rbuf_lines); } if ( args->filter ) filter_destroy(args->filter); free(args->tmpi); free(args->tmp_ac); if ( args->mask ) regidx_destroy(args->mask); } static void flush_buffer(args_t *args, int n) { int i, j; for (i=0; irbuf); bcf1_t *rec = args->rbuf_lines[k]; int pass = 1; if ( !args->soft_filter ) { for (j=0; jd.n_flt; j++) { if ( args->indel_gap && rec->d.flt[j]==args->IndelGap_id ) { pass = 0; break; } if ( args->snp_gap && rec->d.flt[j]==args->SnpGap_id ) { pass = 0; break; } } } if ( pass && bcf_write1(args->out_fh, args->hdr, rec)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } } #define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } static void buffered_filters(args_t *args, bcf1_t *line) { /** * The logic of SnpGap=3. The SNPs at positions 1 and 7 are filtered, * positions 0 and 8 are not: * 0123456789 * ref .G.GT..G.. * del .A.G-..A.. * Here the positions 1 and 6 are filtered, 0 and 7 are not: * 0123-456789 * ref .G.G-..G.. * ins .A.GT..A.. * * The logic of IndelGap=2. The second indel is filtered: * 012345678901 * ref .GT.GT..GT.. * del .G-.G-..G-.. * And similarly here, the second is filtered: * 01 23 456 78 * ref .A-.A-..A-.. * ins .AT.AT..AT.. */ // To avoid additional data structure, we abuse bcf1_t's var and var_type records. const int SnpGap_set = 1 << (8*sizeof(int)/2); const int IndelGap_set = 1 << (8*sizeof(int)/2-1); const int IndelGap_flush = 1 << (8*sizeof(int)/2-2); int var_type = 0, i; if ( line ) { // Still on the same chromosome? int ilast = rbuf_last(&args->rbuf); if ( ilast>=0 && line->rid != args->rbuf_lines[ilast]->rid ) flush_buffer(args, args->rbuf.n); // new chromosome, flush everything rbuf_expand0(&args->rbuf,bcf1_t*,args->rbuf.n,args->rbuf_lines); // Insert the new record in the buffer. The line would be overwritten in // the next bcf_sr_next_line call, therefore we need to swap it with an // unused one ilast = rbuf_append(&args->rbuf); if ( !args->rbuf_lines[ilast] ) args->rbuf_lines[ilast] = bcf_init1(); SWAP(bcf1_t*, args->files->readers[0].buffer[0], args->rbuf_lines[ilast]); var_type = bcf_get_variant_types(line); // Find out the size of an indel. The indel boundaries are based on REF // (POS+1,POS+rlen-1). This is not entirely correct: mpileup likes to // output REF=CAGAGAGAGA, ALT=CAGAGAGAGAGA where REF=C,ALT=CGA could be // used. This filter is therefore more strict and may remove some valid // SNPs. // Set the REF allele's length to max deletion length or to 1 if a SNP or an insertion. line->d.var[0].n = line->rlen; } int k_flush = 1; if ( args->indel_gap ) { k_flush = 0; // Find indels which are too close to each other int last_to = -1; for (i=-1; rbuf_next(&args->rbuf,&i); ) { bcf1_t *rec = args->rbuf_lines[i]; int rec_from = rec->pos; if ( last_to!=-1 && last_to < rec_from ) break; k_flush++; if ( !(rec->d.var_type & VCF_INDEL) ) continue; rec->d.var_type |= IndelGap_set; last_to = args->indel_gap + rec->pos + rec->d.var[0].n - 1; } if ( i==args->rbuf.f && line && last_to!=-1 ) k_flush = 0; if ( k_flush || !line ) { // Select the best indel from the cluster of k_flush indels int k = 0, max_ac = -1, imax_ac = -1, max_qual = -1, imax_qual = -1; for (i=-1; rbuf_next(&args->rbuf,&i) && krbuf_lines[i]; if ( !(rec->d.var_type & IndelGap_set) ) continue; hts_expand(int, rec->n_allele, args->ntmpi, args->tmpi); int ret = bcf_calc_ac(args->hdr, rec, args->tmpi, BCF_UN_ALL); if ( imax_ac==-1 || (ret && max_ac < args->tmpi[1]) ) { max_ac = args->tmpi[1]; imax_ac = i; } if ( imax_qual==-1 || max_qual < rec->qual ) { max_qual = rec->qual; imax_qual = i; } } // Filter all but the best indel (with the best QUAL, bigger AC, or take the first if neither QUAL nor AC are available) k = 0; for (i=-1; rbuf_next(&args->rbuf,&i) && krbuf_lines[i]; if ( !(rec->d.var_type & IndelGap_set) ) continue; rec->d.var_type |= IndelGap_flush; int do_filter = 0; if ( max_qual>0 ) { if ( i!=imax_qual ) do_filter = 1; } else if ( i!=imax_ac ) do_filter = 1; if ( do_filter ) bcf_add_filter(args->hdr, args->rbuf_lines[i], args->IndelGap_id); } } } if ( !line ) { // Finished: flush everything flush_buffer(args, args->rbuf.n); return; } int j_flush = 1; if ( args->snp_gap ) { j_flush = 0; int last_from = line->pos; for (i=-1; rbuf_next(&args->rbuf,&i); ) { bcf1_t *rec = args->rbuf_lines[i]; int rec_to = rec->pos + rec->d.var[0].n - 1; // last position affected by the variant if ( rec_to + args->snp_gap < last_from ) j_flush++; else if ( (var_type & args->snp_gap_type) && (rec->d.var_type & VCF_SNP) && !(rec->d.var_type & SnpGap_set) ) { // this SNP has not been SnpGap-filtered yet rec->d.var_type |= SnpGap_set; bcf_add_filter(args->hdr, rec, args->SnpGap_id); } else if ( (var_type & VCF_SNP) && (rec->d.var_type & args->snp_gap_type) ) { // the line which we are adding is a SNP and needs to be filtered line->d.var_type |= SnpGap_set; bcf_add_filter(args->hdr, line, args->SnpGap_id); break; } } } flush_buffer(args, j_flush < k_flush ? j_flush : k_flush); } static void set_genotypes(args_t *args, bcf1_t *line, int pass_site) { int i,j; if ( !bcf_hdr_nsamples(args->hdr) ) return; if ( args->smpl_pass ) { int npass = 0; for (i=0; ihdr); i++) npass += args->smpl_pass[i]; // return if all samples pass if ( npass==bcf_hdr_nsamples(args->hdr) && (args->filter_logic & FLT_INCLUDE) ) return; if ( npass==0 && (args->filter_logic & FLT_EXCLUDE) ) return; } else if ( pass_site ) return; int an = 0, has_an = bcf_get_info_int32(args->hdr, line, "AN", &args->tmp_ac, &args->ntmp_ac); if ( has_an==1 ) an = args->tmp_ac[0]; else has_an = 0; int has_ac = bcf_get_info_int32(args->hdr, line, "AC", &args->tmp_ac, &args->ntmp_ac); has_ac = has_ac==line->n_allele-1 ? 1 : 0; int new_gt = 0, ngts = bcf_get_format_int32(args->hdr, line, "GT", &args->tmpi, &args->ntmpi); ngts /= bcf_hdr_nsamples(args->hdr); if ( args->set_gts==SET_GTS_MISSING ) new_gt = bcf_gt_missing; else if ( args->set_gts==SET_GTS_REF ) new_gt = bcf_gt_unphased(0); else error("todo: set_gts=%d\n", args->set_gts); for (i=0; ihdr); i++) { if ( args->smpl_pass ) { int pass = args->smpl_pass[i]; if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( pass ) continue; } int32_t *gts = args->tmpi + ngts*i; for (j=0; jset_gts==SET_GTS_MISSING && !bcf_gt_is_missing(gts[j]) ) { int ial = bcf_gt_allele(gts[j]); if ( has_ac && ial>0 && ial<=line->n_allele ) args->tmp_ac[ ial-1 ]--; an--; } else if ( args->set_gts==SET_GTS_REF ) { int ial = bcf_gt_allele(gts[j]); if ( bcf_gt_is_missing(gts[j]) ) an++; else if ( has_ac && ial>0 && ial<=line->n_allele ) args->tmp_ac[ ial-1 ]--; } gts[j] = new_gt; } } bcf_update_genotypes(args->hdr,line,args->tmpi,ngts*bcf_hdr_nsamples(args->hdr)); if ( has_an ) bcf_update_info_int32(args->hdr,line,"AN",&an,1); if ( has_ac ) bcf_update_info_int32(args->hdr,line,"AC",args->tmp_ac,line->n_allele-1); } static void _set_variant_boundaries(bcf1_t *rec, hts_pos_t *beg, hts_pos_t *end) { hts_pos_t off; if ( rec->n_allele ) { off = rec->rlen; bcf_unpack(rec, BCF_UN_STR); int i; for (i=1; in_allele; i++) { // Make symbolic alleles start at POS, although this is not strictly true for // , where POS should be the position BEFORE the deletion/insertion. // However, since arbitrary symbolic alleles can be defined by the user, we // will simplify the interpretation of --targets-overlap and --region-overlap. int j = 0; char *ref = rec->d.allele[0]; char *alt = rec->d.allele[i]; while ( ref[j] && alt[j] && ref[j]==alt[j] ) j++; if ( off > j ) off = j; if ( !off ) break; } } else off = 0; *beg = rec->pos + off; *end = rec->pos + rec->rlen - 1; } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Apply fixed-threshold filters.\n"); fprintf(stderr, "Usage: bcftools filter [options] \n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -g, --SnpGap INT[:TYPE] Filter SNPs within base pairs of an indel (the default) or any combination of indel,mnp,bnd,other,overlap\n"); fprintf(stderr, " -G, --IndelGap INT Filter clusters of indels separated by or fewer base pairs allowing only one to pass\n"); fprintf(stderr, " -i, --include EXPR Include only sites for which the expression is true (see man page for details\n"); fprintf(stderr, " --mask [^]REGION Soft filter regions, \"^\" to negate\n"); fprintf(stderr, " -M, --mask-file [^]FILE Soft filter regions listed in a file, \"^\" to negate\n"); fprintf(stderr, " --mask-overlap 0|1|2 Mask if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -m, --mode [+x] \"+\": do not replace but add to existing FILTER; \"x\": reset filters at sites which pass\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --soft-filter STRING Annotate FILTER column with or unique filter name (\"Filter%%d\") made up by the program (\"+\")\n"); fprintf(stderr, " -S, --set-GTs .|0 Set genotypes of failed samples to missing (.) or ref (0)\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " --threads INT Use multithreading with worker threads [0]\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); exit(1); } int main_vcffilter(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->files = bcf_sr_init(); args->output_fname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->clevel = -1; int regions_is_file = 0, targets_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; args->mask_overlap = 1; static struct option loptions[] = { {"set-GTs",required_argument,NULL,'S'}, {"mode",required_argument,NULL,'m'}, {"mask",required_argument,NULL,10}, {"mask-file",required_argument,NULL,'M'}, {"mask-overlap",required_argument,NULL,11}, {"soft-filter",required_argument,NULL,'s'}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,4}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,3}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"SnpGap",required_argument,NULL,'g'}, {"IndelGap",required_argument,NULL,'G'}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "e:i:t:T:r:R:h?s:m:M:o:O:g:G:S:W::",loptions,NULL)) >= 0) { switch (c) { case 'g': args->snp_gap = strtol(optarg,&tmp,10); if ( *tmp && *tmp!=':' ) error("Could not parse argument: --SnpGap %s\n", optarg); if ( *tmp==':' ) { args->snp_gap_str = tmp+1; int i,n; char **keys = hts_readlist(tmp+1,0,&n); for(i=0; isnp_gap_type |= VCF_INDEL; else if ( !strcasecmp(keys[i],"mnp") ) args->snp_gap_type |= VCF_MNP; else if ( !strcasecmp(keys[i],"bnd") ) args->snp_gap_type |= VCF_BND; else if ( !strcasecmp(keys[i],"other") ) args->snp_gap_type |= VCF_OTHER; else if ( !strcasecmp(keys[i],"overlap") ) args->snp_gap_type |= VCF_OVERLAP; else error("Could not parse \"%s\" in \"--SnpGap %s\"\n", keys[i], optarg); free(keys[i]); } if ( n ) free(keys); } else { args->snp_gap_type = VCF_INDEL; args->snp_gap_str = "indel"; } break; case 'G': args->indel_gap = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --IndelGap %s\n", optarg); break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 's': args->soft_filter = optarg; break; case 'm': if ( strchr(optarg,'x') ) args->annot_mode |= ANNOT_RESET; if ( strchr(optarg,'+') ) args->annot_mode |= ANNOT_ADD; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'S': if ( !strcmp(".",optarg) ) args->set_gts = SET_GTS_MISSING; else if ( !strcmp("0",optarg) ) args->set_gts = SET_GTS_REF; else error("The argument to -S not recognised: %s\n", optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 3 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 10 : args->mask_list = optarg; break; case 'M' : args->mask_list = optarg; args->mask_is_file = 1; break; case 11 : if ( !strcasecmp(optarg,"0") ) args->mask_overlap = 0; else if ( !strcasecmp(optarg,"1") ) args->mask_overlap = 1; else if ( !strcasecmp(optarg,"2") ) args->mask_overlap = 2; else error("Could not parse: --mask-overlap %s\n",optarg); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(args); } else fname = argv[optind]; if ( args->mask_list && !args->soft_filter ) error("The option --soft-filter is required with --mask and --mask-file options\n"); // read in the regions from the command line if ( args->regions_list ) { args->files->require_index = 1; bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } else if ( optind+1 < argc ) { int i; kstring_t tmp = {0,0,0}; kputs(argv[optind+1],&tmp); for (i=optind+2; ifiles->require_index = 1; bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, tmp.s, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); free(tmp.s); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list,targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); init_data(args); if ( bcf_hdr_write(args->out_fh, args->hdr)!=0 ) error("[%s] Error: cannot write the header to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr,args->output_fname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files, 0); int pass = 1; if ( args->filter ) { pass = filter_test(args->filter, line, &args->smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; } if ( args->mask ) { hts_pos_t beg, end; if ( args->mask_overlap==0 ) beg = end = line->pos; else if ( args->mask_overlap==1 ) beg = line->pos, end = line->pos + line->rlen - 1; else _set_variant_boundaries(line,&beg,&end); int mpass = regidx_overlap(args->mask,bcf_seqname(args->hdr,line),beg,end,NULL) ? 0 : 1; if ( args->mask_negate ) mpass = mpass ? 0 : 1; pass &= mpass; } if ( args->soft_filter || args->set_gts || pass ) { if ( pass ) { bcf_unpack(line,BCF_UN_FLT); if ( args->annot_mode & ANNOT_RESET || !line->d.n_flt ) bcf_add_filter(args->hdr, line, args->flt_pass); } else if ( args->soft_filter ) { if ( (args->annot_mode & ANNOT_ADD) ) bcf_add_filter(args->hdr, line, args->flt_fail); else bcf_update_filter(args->hdr, line, &args->flt_fail, 1); } if ( args->set_gts ) set_genotypes(args, line, pass); if ( !args->rbuf_lines ) { if ( bcf_write1(args->out_fh, args->hdr, line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } else buffered_filters(args, line); } } buffered_filters(args, NULL); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); destroy_data(args); bcf_sr_destroy(args->files); free(args); return 0; } bcftools-1.21/vcfgtcheck.c000066400000000000000000001774621467060157400155560ustar00rootroot00000000000000/* vcfgtcheck.c -- Check sample identity. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "extsort.h" //#include "hclust.h" #include "filter.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { int iqry, igt; } pair_t; typedef struct { bcf_srs_t *files; // first reader is the query VCF - single sample normally or multi-sample for cross-check bcf_hdr_t *gt_hdr, *qry_hdr; // VCF with genotypes to compare against and the query VCF char *cwd, **argv, *gt_samples, *qry_samples, *regions, *targets, *qry_fname, *gt_fname, *pair_samples; char *output_fname; int argc, gt_samples_is_file, qry_samples_is_file, regions_is_file, targets_is_file, pair_samples_is_file, output_type;; int regions_overlap, targets_overlap, clevel; int qry_use_GT,gt_use_GT, nqry_smpl,ngt_smpl, *qry_smpl,*gt_smpl; int nused[2][2]; double *pdiff, *qry_prob, *gt_prob; uint32_t *ndiff,*ncnt,*nmatch,ncmp, npairs; int32_t *qry_arr,*gt_arr, nqry_arr,ngt_arr; uint8_t *qry_dsg, *gt_dsg; pair_t *pairs; double *hwe_prob, dsg2prob[8][3], pl2prob[256]; double min_inter_err, max_intra_err; int all_sites, hom_only, ntop, cross_check, calc_hwe_prob, sort_by_hwe, dry_run, gt_err; BGZF *out_fh; unsigned int nskip_no_match, nskip_not_ba, nskip_mono, nskip_no_data, nskip_dip_GT, nskip_dip_PL, nskip_filter; kstring_t kstr; // for --distinctive-sites double distinctive_sites; kbitset_t *kbs_diff; size_t diff_sites_size; extsort_t *es; char *es_tmp_prefix, *es_max_mem; // include or exclude sites which match the filters filter_t *qry_filter, *gt_filter; char *qry_filter_str, *gt_filter_str; int qry_filter_logic, gt_filter_logic; // FLT_INCLUDE or FLT_EXCLUDE } args_t; static void set_cwd(args_t *args) { int i; char *buf; size_t nbuf = 500; args->cwd = (char*) malloc(sizeof(char)*nbuf); for (i=0; i<5; i++) { if ( (buf = getcwd(args->cwd, nbuf)) ) break; nbuf *= 2; args->cwd = (char*) realloc(args->cwd, sizeof(char)*nbuf); } assert(buf); } static void print_header(args_t *args) { args->kstr.l = 0; ksprintf(&args->kstr, "# This file was produced by bcftools (%s+htslib-%s), the command line was:\n", bcftools_version(), hts_version()); ksprintf(&args->kstr, "# \t bcftools %s ", args->argv[0]); int i; for (i=1; iargc; i++) ksprintf(&args->kstr, " %s",args->argv[i]); ksprintf(&args->kstr, "\n# and the working directory was:\n"); ksprintf(&args->kstr, "# \t %s\n#\n", args->cwd); if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); } static int cmp_int(const void *_a, const void *_b) { int a = *((int*)_a); int b = *((int*)_b); if ( a < b ) return -1; if ( a > b ) return 1; return 0; } static int cmp_pair(const void *_a, const void *_b) { pair_t *a = (pair_t*)_a; pair_t *b = (pair_t*)_b; if ( a->iqry < b->iqry ) return -1; if ( a->iqry > b->iqry ) return 1; if ( a->igt < b->igt ) return -1; if ( a->igt > b->igt ) return 1; return 0; } typedef struct { uint32_t ndiff,rid,pos,rand; // rand is to shuffle sites with the same ndiff from across all chromosomes unsigned long kbs_dat[1]; } diff_sites_t; #if DBG static void diff_sites_debug_print(args_t *args, diff_sites_t *ds) { int i; memcpy(args->kbs_diff->b,ds->kbs_dat,args->kbs_diff->n*sizeof(unsigned long)); fprintf(stderr,"%s:%d\t%d\t",bcf_hdr_id2name(args->qry_hdr,ds->rid),ds->pos+1,ds->ndiff); for (i=0; inpairs; i++) fprintf(stderr,"%d",kbs_exists(args->kbs_diff,i)?1:0); fprintf(stderr,"\n"); } #endif static int diff_sites_cmp(const void *aptr, const void *bptr) { diff_sites_t *a = *((diff_sites_t**)aptr); diff_sites_t *b = *((diff_sites_t**)bptr); if ( a->ndiff < b->ndiff ) return 1; // descending order if ( a->ndiff > b->ndiff ) return -1; if ( a->rand < b->rand ) return -1; if ( a->rand > b->rand ) return 1; return 0; } static void diff_sites_init(args_t *args) { int nsites = args->distinctive_sites<=1 ? args->npairs*args->distinctive_sites : args->distinctive_sites; if ( nsites<=0 ) error("The value for --distinctive-sites was set too low: %d\n",nsites); if ( nsites > args->npairs ) { fprintf(stderr,"Warning: The value for --distinctive-sites is bigger than is the number of pairs, all discordant sites be printed.\n"); nsites = args->npairs; args->distinctive_sites = args->npairs + 1; } else args->distinctive_sites = nsites; args->kbs_diff = kbs_init(args->npairs); size_t n = (args->npairs + KBS_ELTBITS-1) / KBS_ELTBITS; assert( n==args->kbs_diff->n ); args->diff_sites_size = sizeof(diff_sites_t) + (n-1)*sizeof(unsigned long); args->es = extsort_alloc(); extsort_set_opt(args->es,size_t,DAT_SIZE,args->diff_sites_size); extsort_set_opt(args->es,const char*,TMP_PREFIX,args->es_tmp_prefix); extsort_set_opt(args->es,const char*,MAX_MEM,args->es_max_mem); extsort_set_opt(args->es,extsort_cmp_f,FUNC_CMP,diff_sites_cmp); extsort_init(args->es); } static void diff_sites_destroy(args_t *args) { kbs_destroy(args->kbs_diff); extsort_destroy(args->es); } static inline void diff_sites_reset(args_t *args) { kbs_clear(args->kbs_diff); } static inline void diff_sites_push(args_t *args, int ndiff, int rid, int pos) { diff_sites_t *dat = (diff_sites_t*) malloc(args->diff_sites_size); memset(dat,0,sizeof(*dat)); // for debugging: prevent warnings about uninitialized memory coming from struct padding (not needed after rand added) dat->ndiff = ndiff; dat->rid = rid; dat->pos = pos; dat->rand = hts_lrand48(); memcpy(dat->kbs_dat,args->kbs_diff->b,args->kbs_diff->n*sizeof(unsigned long)); extsort_push(args->es,dat); } static inline int diff_sites_shift(args_t *args, int *ndiff, int *rid, int *pos) { diff_sites_t *dat = (diff_sites_t*) extsort_shift(args->es); if ( !dat ) return 0; *ndiff = dat->ndiff; *rid = dat->rid; *pos = dat->pos; memcpy(args->kbs_diff->b,dat->kbs_dat,args->kbs_diff->n*sizeof(unsigned long)); return 1; } static void init_samples(char *list, int list_is_file, int **smpl, int *nsmpl, bcf_hdr_t *hdr, char *vcf_fname) { int i; if ( !strcmp(list,"-") ) { *nsmpl = bcf_hdr_nsamples(hdr); *smpl = (int*) malloc(sizeof(**smpl)*(*nsmpl)); for (i=0; i<*nsmpl; i++) (*smpl)[i] = i; return; } char **tmp = hts_readlist(list, list_is_file, nsmpl); if ( !tmp || !*nsmpl ) error("Failed to parse %s\n", list); *smpl = (int*) malloc(sizeof(**smpl)*(*nsmpl)); for (i=0; i<*nsmpl; i++) { int idx = bcf_hdr_id2int(hdr, BCF_DT_SAMPLE, tmp[i]); if ( idx<0 ) error("No such sample in %s: [%s]\n",vcf_fname,tmp[i]); (*smpl)[i] = idx; free(tmp[i]); } free(tmp); qsort(*smpl,*nsmpl,sizeof(**smpl),cmp_int); // check for duplicates for (i=1; i<*nsmpl; i++) if ( (*smpl)[i-1]==(*smpl)[i] ) error("Error: the sample \"%s\" is listed twice in %s\n", hdr->samples[(*smpl)[i]],list); } static void init_data(args_t *args) { hts_srand48(0); args->files = bcf_sr_init(); if ( args->regions ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions, args->regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions); } if ( args->targets ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets, args->targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets); } if ( args->gt_fname ) bcf_sr_set_opt(args->files, BCF_SR_REQUIRE_IDX); if ( !bcf_sr_add_reader(args->files,args->qry_fname) ) error("Failed to open %s: %s\n", args->qry_fname,bcf_sr_strerror(args->files->errnum)); if ( args->gt_fname && !bcf_sr_add_reader(args->files, args->gt_fname) ) error("Failed to read from %s: %s\n", !strcmp("-",args->gt_fname)?"standard input":args->gt_fname,bcf_sr_strerror(args->files->errnum)); args->qry_hdr = bcf_sr_get_header(args->files,0); if ( !bcf_hdr_nsamples(args->qry_hdr) ) error("No samples in %s?\n", args->qry_fname); if ( args->gt_fname ) { args->gt_hdr = bcf_sr_get_header(args->files,1); if ( !bcf_hdr_nsamples(args->gt_hdr) ) error("No samples in %s?\n", args->gt_fname); } if ( args->gt_hdr && args->gt_filter_str ) args->gt_filter = filter_init(args->gt_hdr, args->gt_filter_str); if ( args->qry_hdr && args->qry_filter_str ) args->qry_filter = filter_init(args->qry_hdr, args->qry_filter_str); // Determine whether GT or PL will be used if ( args->qry_use_GT==-1 ) // not set by -u, qry uses PL by default { if ( bcf_hdr_id2int(args->qry_hdr,BCF_DT_ID,"PL")>=0 ) args->qry_use_GT = 0; else if ( bcf_hdr_id2int(args->qry_hdr,BCF_DT_ID,"GT")>=0 ) args->qry_use_GT = 1; else error("[E::%s] Neither PL nor GT tag is present in the header of %s\n", __func__, args->qry_fname); } else if ( args->qry_use_GT==1 ) { if ( bcf_hdr_id2int(args->qry_hdr,BCF_DT_ID,"GT")<0 ) error("[E::%s] The GT tag is not present in the header of %s\n", __func__, args->qry_fname); } else if ( bcf_hdr_id2int(args->qry_hdr,BCF_DT_ID,"PL")<0 ) error("[E::%s] The PL tag is not present in the header of %s\n", __func__, args->qry_fname); if ( args->gt_hdr ) { if ( args->gt_use_GT==-1 ) // not set by -u, gt uses GT by default { if ( bcf_hdr_id2int(args->gt_hdr,BCF_DT_ID,"GT")>=0 ) args->gt_use_GT = 1; else if ( bcf_hdr_id2int(args->gt_hdr,BCF_DT_ID,"PL")>=0 ) args->gt_use_GT = 0; else error("[E::%s] Neither PL nor GT tag is present in the header of %s\n", __func__, args->gt_fname); } else if ( args->gt_use_GT==1 ) { if ( bcf_hdr_id2int(args->gt_hdr,BCF_DT_ID,"GT")<0 ) error("[E::%s] The GT tag is not present in the header of %s\n", __func__, args->gt_fname); } else if ( bcf_hdr_id2int(args->gt_hdr,BCF_DT_ID,"PL")<0 ) error("[E::%s] The PL tag is not present in the header of %s\n", __func__, args->gt_fname); } else args->gt_use_GT = args->qry_use_GT; // Prepare samples int i,j; args->nqry_smpl = bcf_hdr_nsamples(args->qry_hdr); if ( args->qry_samples ) { init_samples(args->qry_samples, args->qry_samples_is_file, &args->qry_smpl, &args->nqry_smpl, args->qry_hdr, args->qry_fname); } if ( args->gt_samples ) { init_samples(args->gt_samples, args->gt_samples_is_file, &args->gt_smpl, &args->ngt_smpl, args->gt_hdr ? args->gt_hdr : args->qry_hdr, args->gt_fname ? args->gt_fname : args->qry_fname); } else if ( args->pair_samples ) { int npairs; char **tmp = hts_readlist(args->pair_samples, args->pair_samples_is_file, &npairs); if ( !tmp || !npairs ) error("Failed to parse %s\n", args->pair_samples); if ( !args->pair_samples_is_file && npairs%2 ) error("Expected even number of comma-delimited samples with -p\n"); args->npairs = args->pair_samples_is_file ? npairs : npairs/2; args->pairs = (pair_t*) calloc(args->npairs,sizeof(*args->pairs)); if ( !args->pair_samples_is_file ) { for (i=0; inpairs; i++) { args->pairs[i].iqry = bcf_hdr_id2int(args->qry_hdr, BCF_DT_SAMPLE, tmp[2*i]); args->pairs[i].igt = bcf_hdr_id2int(args->gt_hdr?args->gt_hdr:args->qry_hdr, BCF_DT_SAMPLE, tmp[2*i+1]); if ( args->pairs[i].iqry < 0 ) error("No such sample in %s: [%s]\n",args->qry_fname,tmp[2*i]); if ( args->pairs[i].igt < 0 ) error("No such sample in %s: [%s]\n",args->gt_fname?args->gt_fname:args->qry_fname,tmp[2*i+1]); free(tmp[2*i]); free(tmp[2*i+1]); } } else { for (i=0; inpairs; i++) { char *ptr = tmp[i]; while ( *ptr && !isspace(*ptr) ) ptr++; if ( !*ptr ) error("Could not parse %s: %s\n",args->pair_samples,tmp[i]); *ptr = 0; args->pairs[i].iqry = bcf_hdr_id2int(args->qry_hdr, BCF_DT_SAMPLE, tmp[i]); if ( args->pairs[i].iqry < 0 ) error("No such sample in %s: [%s]\n",args->qry_fname,tmp[i]); ptr++; while ( *ptr && isspace(*ptr) ) ptr++; args->pairs[i].igt = bcf_hdr_id2int(args->gt_hdr?args->gt_hdr:args->qry_hdr, BCF_DT_SAMPLE, ptr); if ( args->pairs[i].igt < 0 ) error("No such sample in %s: [%s]\n",args->gt_fname?args->gt_fname:args->qry_fname,ptr); free(tmp[i]); } } free(tmp); qsort(args->pairs,args->npairs,sizeof(*args->pairs),cmp_pair); } else if ( args->gt_hdr ) args->ngt_smpl = bcf_hdr_nsamples(args->gt_hdr); if ( !args->ngt_smpl ) { args->ngt_smpl = args->nqry_smpl; args->gt_smpl = args->qry_smpl; args->cross_check = 1; } // The data arrays if ( !args->npairs ) args->npairs = args->cross_check ? args->nqry_smpl*(args->nqry_smpl+1)/2 : args->ngt_smpl*args->nqry_smpl; if ( !args->pair_samples ) { args->qry_dsg = (uint8_t*) malloc(args->nqry_smpl); args->gt_dsg = args->cross_check ? args->qry_dsg : (uint8_t*) malloc(args->ngt_smpl); } if ( args->gt_err ) { args->pdiff = (double*) calloc(args->npairs,sizeof(*args->pdiff)); // log probability of pair samples being the same args->qry_prob = (double*) malloc(3*args->nqry_smpl*sizeof(*args->qry_prob)); args->gt_prob = args->cross_check ? args->qry_prob : (double*) malloc(3*args->ngt_smpl*sizeof(*args->gt_prob)); // Convert genotypes to genotype likelihoods given by -E, the probability of reading one allele incorrectly. In this // simple model we have: // - probability of reading an allele incorrectly, eg. 0 as 1 or 1 as 0 // P(0|1) = P(1|0) = e // - probability of genotype G={00,01,11} being correct given observed dosage {0,1,2} and the // genotyping error probability e: // P(00|0) = 1 P(00|1) = e P(00|2) = e^2 // P(01|0) = e P(01|1) = 1 P(01|2) = e // P(11|0) = e^2 P(11|1) = e P(11|2) = 1 // // dsg2prob: the first index is bitmask of 8 possible dsg combinations (only 1<<0,1<<2,1<<3 are set, accessing // anything else indicated an error, this is just to reuse gt_to_dsg(); the second index are the corresponding // probabilities of 0/0, 0/1, and 1/1 genotypes // for (i=0; i<8; i++) for (j=0; j<3; j++) args->dsg2prob[i][j] = HUGE_VAL; double eprob = pow(10,-0.1*args->gt_err); // convert from phred score to probability args->dsg2prob[1][0] = 0; // P(00|0) = 1 args->dsg2prob[1][1] = -log(eprob); // P(01|0) = e args->dsg2prob[1][2] = -2*log(eprob); // P(11|0) = e^2 args->dsg2prob[2][0] = -log(eprob); // P(00|1) = e args->dsg2prob[2][1] = 0; // P(01|1) = 1 args->dsg2prob[2][2] = -log(eprob); // P(11|1) = e args->dsg2prob[4][0] = -2*log(eprob); // P(00|2) = e^2 args->dsg2prob[4][1] = -log(eprob); // P(01|2) = e args->dsg2prob[4][2] = 0; // P(11|2) = 1 // lookup table to avoid exponentiation for (i=0; i<256; i++) args->pl2prob[i] = pow(10,-0.1*i); } else args->ndiff = (uint32_t*) calloc(args->npairs,sizeof(*args->ndiff)); // number of differing genotypes for each pair of samples args->ncnt = (uint32_t*) calloc(args->npairs,sizeof(*args->ncnt)); // number of comparisons performed (non-missing data) if ( !args->ncnt ) error("Error: failed to allocate %.1f Mb\n", args->npairs*sizeof(*args->ncnt)/1e6); if ( args->calc_hwe_prob ) { // prob of the observed sequence of matches given site AFs and HWE args->hwe_prob = (double*) calloc(args->npairs,sizeof(*args->hwe_prob)); if ( !args->hwe_prob ) error("Error: failed to allocate %.1f Mb. Run with --no-HWE-prob to save some memory.\n", args->npairs*sizeof(*args->hwe_prob)/1e6); args->nmatch = (uint32_t*) calloc(args->npairs,sizeof(*args->ncnt)); // number of matches, used only with calc_hwe_prob if ( !args->nmatch ) error("Error: failed to allocate %.1f Mb.\n", args->npairs*sizeof(*args->ncnt)/1e6); } if ( args->distinctive_sites ) diff_sites_init(args); args->out_fh = bgzf_open(args->output_fname, args->output_type&FT_GZ ? "wg" : "wu"); if ( args->out_fh == NULL ) error("[%s] Error: cannot write to %s: %s\n", __func__,args->output_fname ? args->output_fname : "standard output", strerror(errno)); print_header(args); } static void destroy_data(args_t *args) { free(args->kstr.s); if ( args->gt_filter ) filter_destroy(args->gt_filter); if ( args->qry_filter ) filter_destroy(args->qry_filter); if ( args->gt_dsg!=args->qry_dsg ) free(args->gt_dsg); free(args->qry_dsg); if ( args->gt_prob!=args->qry_prob ) free(args->gt_prob); free(args->qry_prob); free(args->es_max_mem); if ( bgzf_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); if ( args->distinctive_sites ) diff_sites_destroy(args); free(args->hwe_prob); free(args->cwd); free(args->qry_arr); if ( args->gt_hdr ) free(args->gt_arr); free(args->pdiff); free(args->ndiff); free(args->ncnt); free(args->nmatch); free(args->qry_smpl); if ( args->gt_smpl!=args->qry_smpl ) free(args->gt_smpl); free(args->pairs); bcf_sr_destroy(args->files); } static inline uint8_t gt_to_dsg(int32_t *ptr) { if ( bcf_gt_is_missing(ptr[0]) || bcf_gt_is_missing(ptr[1]) || ptr[1]==bcf_int32_vector_end ) return 0; uint8_t dsg = (bcf_gt_allele(ptr[0])?1:0) + (bcf_gt_allele(ptr[1])?1:0); return 1<dsg2prob[dsg][0]; prob[1] = args->dsg2prob[dsg][1]; prob[2] = args->dsg2prob[dsg][2]; } return dsg; } static inline uint8_t pl_to_prob(args_t *args, int32_t *ptr, double *prob) { uint8_t dsg = pl_to_dsg(ptr); if ( dsg ) { prob[0] = (ptr[0]>=0 && ptr[0]<255) ? args->pl2prob[ptr[0]] : args->pl2prob[255]; prob[1] = (ptr[1]>=0 && ptr[1]<255) ? args->pl2prob[ptr[1]] : args->pl2prob[255]; prob[2] = (ptr[2]>=0 && ptr[2]<255) ? args->pl2prob[ptr[2]] : args->pl2prob[255]; double sum = prob[0] + prob[1] + prob[2]; prob[0] /= sum; prob[1] /= sum; prob[2] /= sum; prob[0] = -log(prob[0]); prob[1] = -log(prob[1]); prob[2] = -log(prob[2]); } return dsg; } static int set_data(args_t *args, bcf_hdr_t *hdr, bcf1_t *rec, int32_t **arr, int32_t *narr, int *narr1, int *use_GT) { static int warn_dip_GT = 1; static int warn_dip_PL = 1; int i; for (i=0; i<2; i++) { if ( *use_GT ) { int ret = bcf_get_genotypes(hdr,rec,arr,narr); if ( ret < 0 ) { if ( !i ) { *use_GT = 0; continue; } args->nskip_no_data++; return -1; } if ( ret != 2*bcf_hdr_nsamples(hdr) ) { if ( warn_dip_GT ) { fprintf(stderr,"INFO: skipping %s:%"PRIhts_pos", only diploid FORMAT/GT fields supported. (This is printed only once.)\n", bcf_seqname(hdr,rec),rec->pos+1); warn_dip_GT = 0; } args->nskip_dip_GT++; return -1; } *narr1 = 2; return 0; } int ret = bcf_get_format_int32(hdr,rec,"PL",arr,narr); if ( ret < 0 ) { if ( !i ) { *use_GT = 1; continue; } args->nskip_no_data++; return -1; } if ( ret != 3*bcf_hdr_nsamples(hdr) ) { if ( warn_dip_PL ) { fprintf(stderr,"INFO: skipping %s:%"PRIhts_pos", only diploid FORMAT/PL fields supported. (This is printed only once.)\n", bcf_seqname(hdr,rec),rec->pos+1); warn_dip_PL = 0; } args->nskip_dip_PL++; return -1; } *narr1 = 3; return 0; } return -1; // should never reach } static void process_line(args_t *args) { int i,j,k, nqry1, ngt1, ret; bcf1_t *gt_rec = NULL, *qry_rec = bcf_sr_get_line(args->files,0); // the query file if ( args->qry_filter ) { int pass = filter_test(args->qry_filter, qry_rec, NULL); if ( args->qry_filter_logic==FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { args->nskip_filter++; return; } } int qry_use_GT = args->qry_use_GT; int gt_use_GT = args->gt_use_GT; ret = set_data(args, args->qry_hdr, qry_rec, &args->qry_arr, &args->nqry_arr, &nqry1, &qry_use_GT); if ( ret<0 ) return; if ( args->gt_hdr ) { gt_rec = bcf_sr_get_line(args->files,1); if ( args->gt_filter ) { int pass = filter_test(args->gt_filter, gt_rec, NULL); if ( args->gt_filter_logic==FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { args->nskip_filter++; return; } } ret = set_data(args, args->gt_hdr, gt_rec, &args->gt_arr, &args->ngt_arr, &ngt1, >_use_GT); if ( ret<0 ) return; } else { ngt1 = nqry1; args->gt_arr = args->qry_arr; } // stats: number of compared sites, and used tags args->ncmp++; args->nused[qry_use_GT][gt_use_GT]++; double hwe_dsg[8]; if ( args->calc_hwe_prob ) { int ac[2]; if ( args->gt_hdr ) { if ( bcf_calc_ac(args->gt_hdr, gt_rec, ac, BCF_UN_INFO|BCF_UN_FMT)!=1 ) error("todo: bcf_calc_ac() failed\n"); } else if ( bcf_calc_ac(args->qry_hdr, qry_rec, ac, BCF_UN_INFO|BCF_UN_FMT)!=1 ) error("todo: bcf_calc_ac() failed\n"); // Calculate HWE probability for each possible qry+gt dosage combination. The alternate allele dosage // values returned by gt_to_prob() below are 0,1,2,4 (0=missing, 1<<0, 1<<1, 1<<2). We consider only // biallelic sites, therefore we work with eight genotype combinations. // // The array hwe_dsg is accessed with hwe_dsg[qry_dsg & gt_dsg] and is constructed to account for PL uncertainty // when we encounter less informative PL, such as PL=0,0,10, where multiple dosage values are equally // likely. If we allowed complete uncertainty (PL=0,0,0), we'd have up to eight possible genotype // mask combinations: from e.g. 0=(gt_dsg=1<<0 & qry_dsg=1<<1) to 7=(gt_dsg=1<<0|1<<1|1<<2 & qry_dsg=1<<0|1<<1|1<<2). // Note the extreme case of 1|2|4 is skipped, see pl_to_dsg(). // // When the dosage is uncertain, we take the minimum of their corresponding HWE value, for example // hwe[0] = 0 // hwe[1] = (1-AF)**2 // hwe[2] = 2*AF*(1-AF) // hwe[4] = AF**2 // hwe[3] = min{hwe[1],hwe[2]} double hwe[3]; // while hwe_dsg iterates over dsg bitmasks (0..7), hwe iterates over dsg (0,1,2) double af = ac[0]+ac[1] ? (double)ac[1]/(ac[0]+ac[1]) : 1e-6; hwe[0] = -log((1-af)*(1-af)); hwe[1] = -log(2*af*(1-af)); hwe[2] = -log(af*af); hwe_dsg[0] = 0; for (i=1; i<8; i++) { hwe_dsg[i] = HUGE_VAL; for (k=0; k<3; k++) { if ( ((1< hwe[k] ) hwe_dsg[i] = hwe[k]; } } } // The sample pairs were given explicitly via -p/-P options if ( args->pairs ) { if ( !args->gt_err ) { int ndiff = 0; if ( args->kbs_diff ) diff_sites_reset(args); for (i=0; inpairs; i++) { int32_t *ptr; uint8_t qry_dsg, gt_dsg; ptr = args->gt_arr + args->pairs[i].igt*ngt1; gt_dsg = gt_use_GT ? gt_to_dsg(ptr) : pl_to_dsg(ptr); if ( !gt_dsg ) continue; // missing value if ( args->hom_only && !(gt_dsg&5) ) continue; // not a hom ptr = args->qry_arr + args->pairs[i].iqry*nqry1; qry_dsg = qry_use_GT ? gt_to_dsg(ptr) : pl_to_dsg(ptr); if ( !qry_dsg ) continue; // missing value int match = qry_dsg & gt_dsg; if ( !match ) { args->ndiff[i]++; if ( args->kbs_diff ) { ndiff++; kbs_insert(args->kbs_diff, i); } } else if ( args->calc_hwe_prob ) { args->hwe_prob[i] += hwe_dsg[match]; args->nmatch[i]++; } args->ncnt[i]++; } if ( ndiff ) diff_sites_push(args, ndiff, qry_rec->rid, qry_rec->pos); } else // gt_err set { for (i=0; inpairs; i++) { int32_t *ptr; double qry_prob[3], gt_prob[3]; uint8_t qry_dsg, gt_dsg; ptr = args->gt_arr + args->pairs[i].igt*ngt1; gt_dsg = gt_use_GT ? gt_to_prob(args,ptr,gt_prob) : pl_to_prob(args,ptr,gt_prob); if ( !gt_dsg ) continue; // missing value if ( args->hom_only && !(gt_dsg&5) ) continue; // not a hom ptr = args->qry_arr + args->pairs[i].iqry*nqry1; qry_dsg = qry_use_GT ? gt_to_prob(args,ptr,qry_prob) : pl_to_prob(args,ptr,qry_prob); if ( !qry_dsg ) continue; // missing value double min = qry_prob[0] + gt_prob[0]; qry_prob[1] += gt_prob[1]; if ( min > qry_prob[1] ) min = qry_prob[1]; qry_prob[2] += gt_prob[2]; if ( min > qry_prob[2] ) min = qry_prob[2]; args->pdiff[i] += min; if ( args->calc_hwe_prob ) { int match = qry_dsg & gt_dsg; args->hwe_prob[i] += hwe_dsg[match]; if ( match ) args->nmatch[i]++; } args->ncnt[i]++; } } return; } int idx=0; if ( !args->gt_err ) { for (i=0; inqry_smpl; i++) { int iqry = args->qry_smpl ? args->qry_smpl[i] : i; int32_t *ptr = args->qry_arr + nqry1*iqry; args->qry_dsg[i] = qry_use_GT ? gt_to_dsg(ptr) : pl_to_dsg(ptr); } if ( !args->cross_check ) // in this case gt_dsg points to qry_dsg { for (i=0; ingt_smpl; i++) { int igt = args->gt_smpl ? args->gt_smpl[i] : i; int32_t *ptr = args->gt_arr + ngt1*igt; args->gt_dsg[i] = gt_use_GT ? gt_to_dsg(ptr) : pl_to_dsg(ptr); if ( args->hom_only && !(args->gt_dsg[i]&5) ) args->gt_dsg[i] = 0; // not a hom, set to a missing value } } for (i=0; inqry_smpl; i++) { int ngt = args->cross_check ? i : args->ngt_smpl; // two files or a sub-diagonal cross-check mode? if ( !args->qry_dsg[i] ) { idx += ngt; continue; } // missing value for (j=0; jgt_dsg[j] ) { idx++; continue; } // missing value int match = args->qry_dsg[i] & args->gt_dsg[j]; if ( !match ) args->ndiff[idx]++; else if ( args->calc_hwe_prob ) { args->hwe_prob[idx] += hwe_dsg[match]; args->nmatch[idx]++; } args->ncnt[idx]++; idx++; } } } else // gt_err set { for (i=0; inqry_smpl; i++) { int iqry = args->qry_smpl ? args->qry_smpl[i] : i; int32_t *ptr = args->qry_arr + nqry1*iqry; args->qry_dsg[i] = qry_use_GT ? gt_to_prob(args,ptr,args->qry_prob+i*3) : pl_to_prob(args,ptr,args->qry_prob+i*3); } if ( !args->cross_check ) // in this case gt_dsg points to qry_dsg { for (i=0; ingt_smpl; i++) { int igt = args->gt_smpl ? args->gt_smpl[i] : i; int32_t *ptr = args->gt_arr + ngt1*igt; args->gt_dsg[i] = gt_use_GT ? gt_to_prob(args,ptr,args->gt_prob+i*3) : pl_to_prob(args,ptr,args->gt_prob+i*3); if ( args->hom_only && !(args->gt_dsg[i]&5) ) args->gt_dsg[i] = 0; // not a hom, set to a missing value } } for (i=0; inqry_smpl; i++) { int ngt = args->cross_check ? i : args->ngt_smpl; // two files or a sub-diagonal cross-check mode? if ( !args->qry_dsg[i] ) { idx += ngt; continue; } // missing value for (j=0; jgt_dsg[j] ) { idx++; continue; } // missing value double min = args->qry_prob[i*3] + args->gt_prob[j*3]; if ( min > args->qry_prob[i*3+1] + args->gt_prob[j*3+1] ) min = args->qry_prob[i*3+1] + args->gt_prob[j*3+1]; if ( min > args->qry_prob[i*3+2] + args->gt_prob[j*3+2] ) min = args->qry_prob[i*3+2] + args->gt_prob[j*3+2]; args->pdiff[idx] += min; if ( args->calc_hwe_prob ) { int match = args->qry_dsg[i] & args->gt_dsg[j]; args->hwe_prob[idx] += hwe_dsg[match]; if ( match ) args->nmatch[idx]++; } args->ncnt[idx]++; idx++; } } } } typedef struct { int ism, idx; double val; } idbl_t; static int cmp_idbl(const void *_a, const void *_b) { idbl_t *a = (idbl_t*)_a; idbl_t *b = (idbl_t*)_b; if ( a->val < b->val ) return -1; if ( a->val > b->val ) return 1; return 0; } static void report_distinctive_sites(args_t *args) { extsort_sort(args->es); args->kstr.l = 0; ksprintf(&args->kstr,"# DS, distinctive sites:\n"); ksprintf(&args->kstr,"# - chromosome\n"); ksprintf(&args->kstr,"# - position\n"); ksprintf(&args->kstr,"# - cumulative number of pairs distinguished by this block\n"); ksprintf(&args->kstr,"# - block id\n"); ksprintf(&args->kstr,"#DS\t[2]Chromosome\t[3]Position\t[4]Cumulative number of distinct pairs\t[5]Block id\n"); kbitset_t *kbs_blk = kbs_init(args->npairs); kbitset_iter_t itr; int i,ndiff,rid,pos,ndiff_tot = 0, iblock = 0; int ndiff_min = args->distinctive_sites <= args->npairs ? args->distinctive_sites : args->npairs; while ( diff_sites_shift(args,&ndiff,&rid,&pos) ) { int ndiff_new = 0, ndiff_dbg = 0; kbs_start(&itr); while ( (i=kbs_next(args->kbs_diff, &itr))>=0 ) { ndiff_dbg++; if ( kbs_exists(kbs_blk,i) ) continue; // already set kbs_insert(kbs_blk,i); ndiff_new++; } if ( ndiff_dbg!=ndiff ) error("Corrupted data, fixme: %d vs %d\n",ndiff_dbg,ndiff); if ( !ndiff_new ) continue; // no new pair distinguished by this site ndiff_tot += ndiff_new; args->kstr.l = 0; ksprintf(&args->kstr,"DS\t%s\t%d\t%d\t%d\n",bcf_hdr_id2name(args->qry_hdr,rid),pos+1,ndiff_tot,iblock); if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); if ( ndiff_tot < ndiff_min ) continue; // fewer than the requested number of pairs can be distinguished at this point iblock++; ndiff_tot = 0; kbs_clear(kbs_blk); } kbs_destroy(kbs_blk); } static void report(args_t *args) { args->kstr.l = 0; ksprintf(&args->kstr,"INFO\tsites-compared\t%u\n",args->ncmp); ksprintf(&args->kstr,"INFO\tsites-skipped-no-match\t%u\n",args->nskip_no_match); ksprintf(&args->kstr,"INFO\tsites-skipped-multiallelic\t%u\n",args->nskip_not_ba); ksprintf(&args->kstr,"INFO\tsites-skipped-monoallelic\t%u\n",args->nskip_mono); ksprintf(&args->kstr,"INFO\tsites-skipped-no-data\t%u\n",args->nskip_no_data); ksprintf(&args->kstr,"INFO\tsites-skipped-GT-not-diploid\t%u\n",args->nskip_dip_GT); ksprintf(&args->kstr,"INFO\tsites-skipped-PL-not-diploid\t%u\n",args->nskip_dip_PL); ksprintf(&args->kstr,"INFO\tsites-skipped-filtering-expression\t%u\n",args->nskip_filter); ksprintf(&args->kstr,"INFO\tsites-used-PL-vs-PL\t%u\n",args->nused[0][0]); ksprintf(&args->kstr,"INFO\tsites-used-PL-vs-GT\t%u\n",args->nused[0][1]); ksprintf(&args->kstr,"INFO\tsites-used-GT-vs-PL\t%u\n",args->nused[1][0]); ksprintf(&args->kstr,"INFO\tsites-used-GT-vs-GT\t%u\n",args->nused[1][1]); ksprintf(&args->kstr,"# DCv2, discordance version 2:\n"); ksprintf(&args->kstr,"# - Query sample\n"); ksprintf(&args->kstr,"# - Genotyped sample\n"); ksprintf(&args->kstr,"# - Discordance, given either as an abstract score or number of mismatches, see the options -E/-u\n" "# in man page for details. Note that samples with high missingness have fewer sites compared,\n" "# which results in lower overall discordance. Therefore it is advisable to use the average score\n" "# per site rather than the absolute value, i.e. divide the value by the number of sites compared\n" "# (smaller value = better match)\n"); ksprintf(&args->kstr,"# - Average negative log of HWE probability at matching sites, attempts to quantify the following\n" "# intuition: rare genotype matches are more informative than common genotype matches, hence two\n" "# samples with similar discordance can be further stratified by the HWE score (bigger value = better\n" "# match, the observed concordance was less likely to occur by chance)\n"); ksprintf(&args->kstr,"# - Number of sites compared for this pair of samples (bigger = more informative)\n"); ksprintf(&args->kstr,"# - Number of matching genotypes\n"); ksprintf(&args->kstr,"#DCv2\t[2]Query Sample\t[3]Genotyped Sample\t[4]Discordance\t[5]Average -log P(HWE)\t[6]Number of sites compared\t[7]Number of matching genotypes\n"); if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); int trim = args->ntop; if ( !args->pairs ) { if ( !args->ngt_smpl && args->nqry_smpl <= args->ntop ) trim = 0; if ( args->ngt_smpl && args->ngt_smpl <= args->ntop ) trim = 0; } if ( args->pairs ) { int i; for (i=0; inpairs; i++) { args->kstr.l = 0; int iqry = args->pairs[i].iqry; int igt = args->pairs[i].igt; if ( args->ndiff ) { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%u\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->gt_hdr?args->gt_hdr->samples[igt]:args->qry_hdr->samples[igt], args->ndiff[i], (args->calc_hwe_prob && args->nmatch[i]) ? args->hwe_prob[i]/args->nmatch[i] : 0, args->ncnt[i], args->nmatch[i]); } else { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%e\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->gt_hdr?args->gt_hdr->samples[igt]:args->qry_hdr->samples[igt], args->pdiff[i], (args->calc_hwe_prob && args->nmatch[i]) ? args->hwe_prob[i]/args->nmatch[i] : 0, args->ncnt[i], args->nmatch[i]); } if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); } } else if ( !trim ) { int i,j,idx=0; for (i=0; inqry_smpl; i++) { int iqry = args->qry_smpl ? args->qry_smpl[i] : i; int ngt = args->cross_check ? i : args->ngt_smpl; for (j=0; jkstr.l = 0; int igt = args->gt_smpl ? args->gt_smpl[j] : j; if ( args->ndiff ) { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%u\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->gt_hdr?args->gt_hdr->samples[igt]:args->qry_hdr->samples[igt], args->ndiff[idx], (args->calc_hwe_prob && args->nmatch[idx]) ? args->hwe_prob[idx]/args->nmatch[idx] : 0, args->ncnt[idx], args->calc_hwe_prob ? args->nmatch[idx] : 0); } else { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%e\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->gt_hdr?args->gt_hdr->samples[igt]:args->qry_hdr->samples[igt], args->pdiff[idx], (args->calc_hwe_prob && args->nmatch[idx]) ? args->hwe_prob[idx]/args->nmatch[idx] : 0, args->ncnt[idx], args->calc_hwe_prob ? args->nmatch[idx] : 0); } if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); idx++; } } } else if ( !args->cross_check ) { idbl_t *arr = (idbl_t*)malloc(sizeof(*arr)*args->ngt_smpl); int i,j; for (i=0; inqry_smpl; i++) { int idx = i*args->ngt_smpl; for (j=0; jngt_smpl; j++) { if ( args->sort_by_hwe ) arr[j].val = args->nmatch[idx] ? -args->hwe_prob[idx]/args->nmatch[idx] : 0; // -args->hwe_prob[idx]; else if ( args->ndiff ) arr[j].val = args->ncnt[idx] ? (double)args->ndiff[idx]/args->ncnt[idx] : 0; else arr[j].val = args->ncnt[idx] ? args->pdiff[idx]/args->ncnt[idx] : 0; arr[j].ism = j; arr[j].idx = idx; idx++; } qsort(arr, args->ngt_smpl, sizeof(*arr), cmp_idbl); int iqry = args->qry_smpl ? args->qry_smpl[i] : i; for (j=0; jntop; j++) { args->kstr.l = 0; int idx = arr[j].idx; int igt = args->gt_smpl ? args->gt_smpl[arr[j].ism] : arr[j].ism; if ( args->ndiff ) { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%u\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->gt_hdr?args->gt_hdr->samples[igt]:args->qry_hdr->samples[igt], args->ndiff[idx], (args->calc_hwe_prob && args->nmatch[idx]) ? args->hwe_prob[idx]/args->nmatch[idx] : 0, args->ncnt[idx], args->calc_hwe_prob ? args->nmatch[idx] : 0); } else { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%e\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->gt_hdr?args->gt_hdr->samples[igt]:args->qry_hdr->samples[igt], args->pdiff[idx], (args->calc_hwe_prob && args->nmatch[idx]) ? args->hwe_prob[idx]/args->nmatch[idx] : 0, args->ncnt[idx], args->calc_hwe_prob ? args->nmatch[idx] : 0); } if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); } } free(arr); } else { int narr = args->nqry_smpl-1; idbl_t *arr = (idbl_t*)malloc(sizeof(*arr)*narr); int i,j,k,idx; for (i=0; inqry_smpl; i++) { k = 0, idx = i*(i-1)/2; for (j=0; jsort_by_hwe ) arr[k].val = args->nmatch[idx] ? -args->hwe_prob[idx]/args->nmatch[idx] : 0; else if ( args->ndiff ) arr[k].val = args->ncnt[idx] ? (double)args->ndiff[idx]/args->ncnt[idx] : 0; else arr[k].val = args->ncnt[idx] ? args->pdiff[idx]/args->ncnt[idx] : 0; arr[k].ism = j; arr[k].idx = idx; idx++; k++; } for (; jsort_by_hwe ) arr[k].val = args->nmatch[idx] ? -args->hwe_prob[idx]/args->nmatch[idx] : 0; else if ( args->ndiff ) arr[k].val = args->ncnt[idx] ? (double)args->ndiff[idx]/args->ncnt[idx] : 0; else arr[k].val = args->ncnt[idx] ? args->pdiff[idx]/args->ncnt[idx] : 0; arr[k].ism = j + 1; arr[k].idx = idx; k++; } qsort(arr, narr, sizeof(*arr), cmp_idbl); int iqry = args->qry_smpl ? args->qry_smpl[i] : i; for (j=0; jntop; j++) { args->kstr.l = 0; if ( i <= arr[j].ism ) continue; int idx = arr[j].idx; int igt = args->qry_smpl ? args->qry_smpl[arr[j].ism] : arr[j].ism; if ( args->ndiff ) { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%u\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->qry_hdr->samples[igt], args->ndiff[idx], (args->calc_hwe_prob && args->nmatch[idx]) ? args->hwe_prob[idx]/args->nmatch[idx] : 0, args->ncnt[idx], args->calc_hwe_prob ? args->nmatch[idx] : 0); } else { ksprintf(&args->kstr,"DCv2\t%s\t%s\t%e\t%e\t%u\t%u\n", args->qry_hdr->samples[iqry], args->qry_hdr->samples[igt], args->pdiff[idx], (args->calc_hwe_prob && args->nmatch[idx]) ? args->hwe_prob[idx]/args->nmatch[idx] : 0, args->ncnt[idx], args->calc_hwe_prob ? args->nmatch[idx] : 0); } if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); } } free(arr); } } static int is_input_okay(args_t *args, int nmatch) { int i; const char *msg; bcf_hdr_t *hdr; bcf1_t *rec; if ( args->gt_hdr && nmatch!=2 ) { if ( args->nskip_no_match++ ) return 0; for (i=0; i<2; i++) { rec = bcf_sr_get_line(args->files,i); if ( rec ) break; } hdr = bcf_sr_get_header(args->files,i); fprintf(stderr,"INFO: skipping %s:%"PRIhts_pos", no record with matching POS+ALT. (This is printed only once.)\n", bcf_seqname(hdr,rec),rec->pos+1); return 0; } for (i=0; i<2; i++) { hdr = bcf_sr_get_header(args->files,i); rec = bcf_sr_get_line(args->files,i); if ( rec->n_allele>2 ) { if ( args->nskip_not_ba++ ) return 0; msg = "not a biallelic site, run `bcftools norm -m -` first"; goto not_okay; } if ( bcf_get_variant_types(rec)==VCF_REF ) { if ( args->nskip_mono++ ) return 0; msg = "monoallelic site"; goto not_okay; } if ( !args->gt_hdr ) break; } return 1; not_okay: fprintf(stderr,"INFO: skipping %s:%"PRIhts_pos", %s. (This is printed only once.)\n", bcf_seqname(hdr,rec),rec->pos+1,msg); return 0; } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Check sample identity. With no -g BCF given, multi-sample cross-check is performed.\n"); fprintf(stderr, "Usage: bcftools gtcheck [options] [-g ] \n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); //fprintf(stderr, " -a, --all-sites Output comparison for all sites\n"); //fprintf(stderr, " -c, --cluster MIN,MAX Min inter- and max intra-sample error [0.23,-0.3]\n"); fprintf(stderr, " --distinctive-sites Find sites that can distinguish between at least NUM sample pairs.\n"); fprintf(stderr, " NUM[,MEM[,TMP]] If the number is smaller or equal to 1, it is interpreted as the fraction of pairs.\n"); fprintf(stderr, " The optional MEM string sets the maximum memory used for in-memory sorting [500M]\n"); #ifdef _WIN32 fprintf(stderr, " and TMP is a prefix of temporary files used by external sorting [/bcftools.XXXXXX]\n"); #else fprintf(stderr, " and TMP is a prefix of temporary files used by external sorting [/tmp/bcftools.XXXXXX]\n"); #endif fprintf(stderr, " --dry-run Stop after first record to estimate required time\n"); fprintf(stderr, " -E, --error-probability INT Phred-scaled probability of genotyping error, 0 for faster but less accurate results [40]\n"); fprintf(stderr, " -e, --exclude [qry|gt]:EXPR Exclude sites for which the expression is true\n"); fprintf(stderr, " -g, --genotypes FILE Genotypes to compare against\n"); fprintf(stderr, " -H, --homs-only Homozygous genotypes only, useful with low coverage data (requires -g)\n"); fprintf(stderr, " -i, --include [qry|gt]:EXPR Include sites for which the expression is true\n"); fprintf(stderr, " --n-matches INT Print only top INT matches for each sample (sorted by average score), 0 for unlimited.\n"); fprintf(stderr, " Use negative value to sort by HWE probability rather than by discordance [0]\n"); fprintf(stderr, " --no-HWE-prob Disable calculation of HWE probability\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type t|z t: plain tab-delimited text output, z: compressed [t]\n"); fprintf(stderr, " -p, --pairs LIST Comma-separated sample pairs to compare (qry,gt[,qry,gt..] with -g or qry,qry[,qry,qry..] w/o)\n"); fprintf(stderr, " -P, --pairs-file FILE File with tab-delimited sample pairs to compare (qry,gt with -g or qry,qry w/o)\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples [qry|gt]:LIST List of query or -g samples, \"-\" to select all samples (by default all samples are compared)\n"); fprintf(stderr, " -S, --samples-file [qry|gt]:FILE File with the query or -g samples to compare\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " -u, --use TAG1[,TAG2] Which tag to use in the query file (TAG1) and the -g file (TAG2) [PL,GT]\n"); fprintf(stderr, "Examples:\n"); fprintf(stderr, " # Check discordance of all samples from B against all samples in A\n"); fprintf(stderr, " bcftools gtcheck -g A.bcf B.bcf\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Limit comparisons to the given list of samples\n"); fprintf(stderr, " bcftools gtcheck -s gt:a1,a2,a3 -s qry:b1,b2 -g A.bcf B.bcf\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Compare only two pairs a1,b1 and a1,b2\n"); fprintf(stderr, " bcftools gtcheck -p a1,b1,a1,b2 -g A.bcf B.bcf\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfgtcheck(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; set_cwd(args); args->qry_use_GT = -1; args->gt_use_GT = -1; args->calc_hwe_prob = 1; args->gt_err = 40; args->regions_overlap = 1; args->targets_overlap = 0; args->output_fname = "-"; // external sort for --distinctive-sites #ifdef _WIN32 args->es_tmp_prefix = NULL; #else args->es_tmp_prefix = "/tmp/bcftools-gtcheck"; #endif args->es_max_mem = strdup("500M"); // In simulated sample swaps the minimum error was 0.3 and maximum intra-sample error was 0.23 // - min_inter: pairs with smaller err value will be considered identical // - max_intra: pairs with err value bigger than abs(max_intra_err) will be considered // different. If negative, the cutoff may be heuristically lowered args->min_inter_err = 0.23; args->max_intra_err = -0.3; static struct option loptions[] = { {"error-probability",1,0,'E'}, // note this used to be 'e', but can easily auto-detect to assure backward compatibility {"exclude",required_argument,0,'e'}, {"include",required_argument,0,'i'}, {"output",required_argument,0,'o'}, {"output-type",required_argument,NULL,'O'}, {"use",1,0,'u'}, {"cluster",1,0,'c'}, {"GTs-only",1,0,'G'}, {"all-sites",0,0,'a'}, {"homs-only",0,0,'H'}, {"help",0,0,'h'}, {"genotypes",1,0,'g'}, {"plot",1,0,'p'}, {"samples",1,0,'s'}, {"samples-file",1,0,'S'}, {"n-matches",1,0,2}, {"no-HWE-prob",0,0,3}, {"target-sample",1,0,4}, {"dry-run",0,0,5}, {"distinctive-sites",1,0,6}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,7}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,8}, {"pairs",1,0,'p'}, {"pairs-file",1,0,'P'}, {0,0,0,0} }; char *tmp; while ((c = getopt_long(argc, argv, "hg:p:s:S:p:P:Hr:R:at:T:G:c:u:e:E:i:o:O:",loptions,NULL)) >= 0) { switch (c) { case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 't': args->output_type = FT_TAB_TEXT; break; case 'z': args->output_type = FT_VCF_GZ; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --output-type %s\n", optarg+1); } break; case 'e': if ( !strncasecmp("gt:",optarg,3) ) { if ( args->gt_filter_str ) error("Error: only one -i or -e expression can be given for gt:, and they cannot be combined\n"); args->gt_filter_str = optarg; args->gt_filter_logic |= FLT_EXCLUDE; } else if ( !strncasecmp("qry:",optarg,4) ) { if ( args->qry_filter_str ) error("Error: only one -i or -e expression can be given for qry:, and they cannot be combined\n"); args->qry_filter_str = optarg; args->qry_filter_logic |= FLT_EXCLUDE; } else { // this could be the old -e, --error-probability option args->gt_err = strtol(optarg,&tmp,10); if ( !tmp || *tmp ) { // it is not args->gt_filter_str = optarg; args->qry_filter_str = optarg; args->gt_filter_logic |= FLT_EXCLUDE; args->qry_filter_logic |= FLT_EXCLUDE; } else { fprintf(stderr,"[warning] auto-detected the old format --error-probability option, please switch from -e to -E.\n"); } } break; case 'i': if ( !strncasecmp("gt:",optarg,3) ) { if ( args->gt_filter_str ) error("Error: only one -i or -e expression can be given for gt:, and they cannot be combined\n"); args->gt_filter_str = optarg; args->gt_filter_logic |= FLT_INCLUDE; } else if ( !strncasecmp("qry:",optarg,4) ) { if ( args->qry_filter_str ) error("Error: only one -i or -e expression can be given for qry:, and they cannot be combined\n"); args->qry_filter_str = optarg; args->qry_filter_logic |= FLT_INCLUDE; } else { args->gt_filter_str = optarg; args->qry_filter_str = optarg; args->gt_filter_logic |= FLT_INCLUDE; args->qry_filter_logic |= FLT_INCLUDE; } break; case 'E': args->gt_err = strtol(optarg,&tmp,10); if ( !tmp || *tmp ) error("Could not parse: --error-probability %s\n", optarg); break; case 'u': { int i,nlist; char **list = hts_readlist(optarg, 0, &nlist); if ( !list || nlist<=0 || nlist>2 ) error("Failed to parse --use %s\n", optarg); if ( !strcasecmp("GT",list[0]) ) args->qry_use_GT = 1; else if ( !strcasecmp("PL",list[0]) ) args->qry_use_GT = 0; else error("Failed to parse --use %s; only GT and PL are supported\n", optarg); if ( nlist==2 ) { if ( !strcasecmp("GT",list[1]) ) args->gt_use_GT = 1; else if ( !strcasecmp("PL",list[1]) ) args->gt_use_GT = 0; else error("Failed to parse --use %s; only GT and PL are supported\n", optarg); } else args->gt_use_GT = args->qry_use_GT; for (i=0; intop = strtol(optarg,&tmp,10); if ( !tmp || *tmp ) error("Could not parse: --n-matches %s\n", optarg); if ( args->ntop < 0 ) { args->sort_by_hwe = 1; args->ntop *= -1; } break; case 3 : args->calc_hwe_prob = 0; break; case 4 : error("The option -S, --target-sample has been deprecated\n"); break; case 5 : args->dry_run = 1; break; case 6 : args->distinctive_sites = strtod(optarg,&tmp); if ( *tmp ) { if ( *tmp!=',' ) error("Could not parse: --distinctive-sites %s\n", optarg); tmp++; free(args->es_max_mem); args->es_max_mem = strdup(tmp); while ( *tmp && *tmp!=',' ) tmp++; if ( *tmp ) { *tmp = 0; args->es_tmp_prefix = tmp+1; } } args->gt_err = 0; break; case 'c': error("The -c option is to be implemented, please open an issue on github\n"); args->min_inter_err = strtod(optarg,&tmp); if ( *tmp ) { if ( *tmp!=',') error("Could not parse: -c %s\n", optarg); args->max_intra_err = strtod(tmp+1,&tmp); if ( *tmp ) error("Could not parse: -c %s\n", optarg); } break; case 'G': error("The option -G, --GTs-only has been deprecated\n"); break; case 'a': args->all_sites = 1; error("The -a option is to be implemented, please open an issue on github\n"); break; case 'H': args->hom_only = 1; break; case 'g': args->gt_fname = optarg; break; // case 'p': args->plot = optarg; break; case 's': if ( !strncasecmp("gt:",optarg,3) ) args->gt_samples = optarg+3; else if ( !strncasecmp("qry:",optarg,4) ) args->qry_samples = optarg+4; else error("Which one? Query samples (qry:%s) or genotype samples (gt:%s)?\n",optarg,optarg); break; case 'S': if ( !strncasecmp("gt:",optarg,3) ) args->gt_samples = optarg+3, args->gt_samples_is_file = 1; else if ( !strncasecmp("qry:",optarg,4) ) args->qry_samples = optarg+4, args->qry_samples_is_file = 1; else error("Which one? Query samples (qry:%s) or genotype samples (gt:%s)?\n",optarg,optarg); break; case 'p': args->pair_samples = optarg; break; case 'P': args->pair_samples = optarg; args->pair_samples_is_file = 1; break; case 'r': args->regions = optarg; break; case 'R': args->regions = optarg; args->regions_is_file = 1; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; args->targets_is_file = 1; break; case 7 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 8 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->qry_fname = "-"; // reading from stdin else usage(); // no files given } else args->qry_fname = argv[optind]; if ( argc>optind+1 ) error("Error: too many files given, run with -h for help\n"); // too many files given if ( args->pair_samples ) { if ( args->gt_samples || args->qry_samples ) error("The -p/-P option cannot be combined with -s/-S\n"); if ( args->ntop ) error("The --n-matches option cannot be combined with -p/-P\n"); } if ( args->distinctive_sites && !args->pair_samples ) error("The experimental option --distinctive-sites requires -p/-P\n"); if ( args->hom_only && !args->gt_fname ) error("The option --homs-only requires --genotypes\n"); if ( args->distinctive_sites && args->gt_err ) error("The option --distinctive-sites cannot be combined with --error-probability\n"); init_data(args); int ret; while ( (ret=bcf_sr_next_line(args->files)) ) { if ( !is_input_okay(args,ret) ) continue; // time one record to give the user an estimate with very big files struct timeval t0, t1; if ( !args->ncmp ) gettimeofday(&t0, NULL); process_line(args); if ( args->ncmp==1 ) { gettimeofday(&t1, NULL); double delta = (t1.tv_sec - t0.tv_sec) * 1e6 + (t1.tv_usec - t0.tv_usec); fprintf(stderr,"INFO:\tTime required to process one record .. %f seconds\n",delta/1e6); args->kstr.l = 0; ksprintf(&args->kstr,"INFO\tTime required to process one record .. %f seconds\n",delta/1e6); if ( bgzf_write(args->out_fh, args->kstr.s, args->kstr.l)!=args->kstr.l ) error("Failed to write to %s\n", args->output_fname); if ( args->dry_run ) break; } } if ( !args->dry_run ) { report(args); if ( args->distinctive_sites ) report_distinctive_sites(args); } destroy_data(args); free(args); return 0; } bcftools-1.21/vcfhead.c000066400000000000000000000116311467060157400150300ustar00rootroot00000000000000/* vcfhead.c -- view VCF/BCF file headers. Copyright (C) 2021 University of Glasgow. Copyright (C) 2023 Genome Research Ltd. Author: John Marshall Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include "bcftools.h" int main_vcfhead(int argc, char *argv[]) { static const char usage[] = "\n" "About: Displays VCF/BCF headers and optionally the first few variant records\n" "Usage: bcftools head [OPTION]... [FILE]\n" "\n" "Options:\n" " -h, --headers INT Display INT header lines [all]\n" " -n, --records INT Display INT variant record lines [none]\n" " -s, --samples INT Display INT records starting with the #CHROM header line [none]\n" "\n"; static const struct option loptions[] = { { "headers", required_argument, NULL, 'h' }, { "records", required_argument, NULL, 'n' }, { "samples", required_argument, NULL, 's' }, { NULL, 0, NULL, 0 } }; int all_headers = 1; int samples = 0; uint64_t nheaders = 0; uint64_t nrecords = 0; int c, nargs; while ((c = getopt_long(argc, argv, "h:n:s:", loptions, NULL)) >= 0) switch (c) { case 'h': all_headers = 0; nheaders = strtoull(optarg, NULL, 0); break; case 'n': nrecords = strtoull(optarg, NULL, 0); break; case 's': nrecords = strtoull(optarg, NULL, 0); samples = 1; break; default: fputs(usage, stderr); return EXIT_FAILURE; } if ( samples && all_headers ) all_headers = 0; nargs = argc - optind; if (nargs == 0 && isatty(STDIN_FILENO)) { fputs(usage, stdout); return EXIT_SUCCESS; } else if (nargs > 1) { fputs(usage, stderr); return EXIT_FAILURE; } const char *fname = (nargs == 1)? argv[optind] : "-"; vcfFile *fp = bcf_open(fname, "r"); if (fp == NULL) { if (strcmp(fname, "-") != 0) error_errno("[%s] Can't open \"%s\"", __func__, fname); else error_errno("[%s] Can't open standard input", __func__); } bcf_hdr_t *hdr = bcf_hdr_read(fp); if (hdr == NULL) { bcf_close(fp); if (strcmp(fname, "-") != 0) error("[%s] Can't read headers from \"%s\"\n", __func__, fname); else error("[%s] Can't read headers\n", __func__); } kstring_t str = KS_INITIALIZE; if (all_headers) { bcf_hdr_format(hdr, 0, &str); fputs(ks_str(&str), stdout); } else if (nheaders > 0 || samples ) { bcf_hdr_format(hdr, 0, &str); char *lim = str.s; uint64_t n; int samples_printed = 0; for (n = 0; n < nheaders; n++) { if ( samples && !strncmp(lim,"#CHROM\t",7) ) samples_printed = 1; lim = strchr(lim, '\n'); if (lim) lim++; else break; } if ( nheaders ) { char tmp; if (lim) { tmp = *lim; *lim = '\0'; } fputs(ks_str(&str), stdout); if (lim) *lim = tmp; } if ( lim && samples && !samples_printed ) { while ( lim && *lim ) { if ( !strncmp(lim,"#CHROM\t",7) ) { fputs(lim, stdout); break; } lim = strchr(lim, '\n'); if (lim) lim++; else break; } } } if (nrecords > 0) { bcf1_t *rec = bcf_init(); uint64_t n; for (n = 0; n < nrecords && bcf_read(fp, hdr, rec) >= 0; n++) { ks_clear(&str); if (vcf_format(hdr, rec, &str) >= 0) fputs(ks_str(&str), stdout); else fprintf(stderr, "[%s] Record #%"PRIu64 " is invalid\n", __func__, n+1); } bcf_destroy(rec); } ks_free(&str); bcf_hdr_destroy(hdr); bcf_close(fp); return EXIT_SUCCESS; } bcftools-1.21/vcfindex.c000066400000000000000000000273361467060157400152470ustar00rootroot00000000000000/* vcfindex.c -- Index bgzip compressed VCF/BCF files for random access. Copyright (C) 2014-2024 Genome Research Ltd. Author: Shane McCarthy Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #define __STDC_FORMAT_MACROS #include #include #include #include "bcftools.h" #define BCF_LIDX_SHIFT 14 enum { per_contig = 1, all_contigs = 2, total = 4 }; static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Index bgzip compressed VCF/BCF files for random access.\n"); fprintf(stderr, "Usage: bcftools index [options] |\n"); fprintf(stderr, "\n"); fprintf(stderr, "Indexing options:\n"); fprintf(stderr, " -c, --csi generate CSI-format index for VCF/BCF files [default]\n"); fprintf(stderr, " -f, --force overwrite index if it already exists\n"); fprintf(stderr, " -m, --min-shift INT set minimal interval size for CSI indices to 2^INT [14]\n"); fprintf(stderr, " -o, --output FILE optional output index file name\n"); fprintf(stderr, " -t, --tbi generate TBI-format index for VCF files\n"); fprintf(stderr, " --threads INT use multithreading with INT worker threads [0]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Stats options:\n"); fprintf(stderr, " -a, --all with --stats, print stats for all contigs even when zero\n"); fprintf(stderr, " -n, --nrecords print number of records based on existing index file\n"); fprintf(stderr, " -s, --stats print per contig stats based on existing index file\n"); fprintf(stderr, "\n"); exit(1); } int vcf_index_stats(char *fname, int stats) { const char **seq = NULL; int tid, nseq = 0, ret = 0; tbx_t *tbx = NULL; bcf_hdr_t *hdr = NULL; hts_idx_t *idx = NULL; htsFile *fp = NULL; uint64_t sum = 0; char *fntemp = NULL, *fnidx = NULL; /* * First, has the user provided an index file? If per contig stats * are requested, open the variant file (together with the index file, * if provided), since the contig names can only be retrieved from its * header. Otherwise, use just the corresponding index file to count * the total number of records. */ int len = strlen(fname); int idx_only = 0; if ( (fnidx = strstr(fname, HTS_IDX_DELIM)) != NULL ) { fntemp = strdup(fname); if ( !fntemp ) return 1; fntemp[fnidx-fname] = 0; fname = fntemp; fnidx += strlen(HTS_IDX_DELIM); } else if ( len>4 && (!strcasecmp(".csi",fname+len-4) || !strcasecmp(".tbi",fname+len-4)) ) { fnidx = fname; fntemp = strdup(fname); fname = fntemp; fname[len-4] = 0; idx_only = 1; } if ( stats&per_contig ) { if ( idx_only ) { struct stat buf; if ( stat(fname, &buf)==0 ) idx_only = 0; } enum htsExactFormat fmt; if ( !idx_only ) { fp = hts_open(fname,"r"); if ( !fp ) { fprintf(stderr,"Could not read %s\n", fname); ret = 1; goto cleanup; } hdr = bcf_hdr_read(fp); if ( !hdr ) { fprintf(stderr,"Could not read the header: %s\n", fname); ret = 1; goto cleanup; } fmt = hts_get_format(fp)->format; } else { int len = strlen(fnidx); if ( !strcasecmp(".tbi",fnidx+len-4) ) fmt = vcf; else fmt = bcf; } if ( fmt==vcf ) { tbx = tbx_index_load2(fname, fnidx); if ( !tbx ) { fprintf(stderr,"Could not load index for VCF: %s\n", fname); return 1; } } else if ( fmt==bcf ) { idx = bcf_index_load2(fname, fnidx); if ( !idx ) { fprintf(stderr,"Could not load index for BCF file: %s\n", fname); return 1; } } else { fprintf(stderr,"Could not detect the file type as VCF or BCF: %s\n", fname); return 1; } } else if ( fnidx ) { char *ext = strrchr(fnidx, '.'); if ( ext && strcmp(ext, ".tbi") == 0 ) { tbx = tbx_index_load2(fname, fnidx); } else if ( ext && strcmp(ext, ".csi") == 0 ) { idx = bcf_index_load2(fname, fnidx); } if ( !tbx && !idx ) { fprintf(stderr,"Could not load index file '%s'\n", fnidx); ret = 1; goto cleanup; } } else { char *ext = strrchr(fname, '.'); if ( ext && strcmp(ext, ".bcf") == 0 ) { idx = bcf_index_load(fname); } else if ( ext && (ext-fname) > 4 && strcmp(ext-4, ".vcf.gz") == 0 ) { tbx = tbx_index_load(fname); } } if ( !tbx && !idx ) { fprintf(stderr,"No index file could be found for '%s'. Use 'bcftools index' to create one\n", fname); ret = 1; goto cleanup; } if ( tbx ) { seq = tbx_seqnames(tbx, &nseq); } else { nseq = hts_idx_nseq(idx); } if ( !tbx && !hdr ) fprintf(stderr,"Warning: cannot determine contig names given the .csi index alone\n"); for (tid=0; tididx : idx, tid, &records, &v); sum += records; if ( (stats&total) || (records == 0 && !(stats&all_contigs)) ) continue; const char *ctg_name = tbx ? seq[tid] : hdr ? bcf_hdr_id2name(hdr, tid) : "n/a"; bcf_hrec_t *hrec = hdr ? bcf_hdr_get_hrec(hdr, BCF_HL_CTG, "ID", ctg_name, NULL) : NULL; int hkey = hrec ? bcf_hrec_find_key(hrec, "length") : -1; printf("%s\t%s\t", ctg_name, hkey<0?".":hrec->vals[hkey]); if (ret >= 0) printf("%" PRIu64 "\n", records); else printf(".\n"); } if ( !sum ) { // No counts found. // Is this because index version has no stored count data, or no records? bcf1_t *rec = bcf_init1(); if (fp && hdr && rec && bcf_read1(fp, hdr, rec) >= 0) { fprintf(stderr,"index of %s does not contain any count metadata. Please re-index with a newer version of bcftools or tabix.\n", fname); ret = 1; } bcf_destroy1(rec); } if ( (stats&total) && !ret ) { printf("%" PRIu64 "\n", sum); } cleanup: free(seq); free(fntemp); if ( fp && hts_close(fp)!=0 ) error("[%s] Error: close failed\n", __func__); bcf_hdr_destroy(hdr); if (tbx) tbx_destroy(tbx); if (idx) hts_idx_destroy(idx); return ret; } int main_vcfindex(int argc, char *argv[]) { int c, force = 0, tbi = 0, stats = 0, n_threads = 0; int min_shift = BCF_LIDX_SHIFT; char *outfn = NULL; static struct option loptions[] = { {"all",no_argument,NULL,'a'}, {"csi",no_argument,NULL,'c'}, {"tbi",no_argument,NULL,'t'}, {"force",no_argument,NULL,'f'}, {"min-shift",required_argument,NULL,'m'}, {"stats",no_argument,NULL,'s'}, {"nrecords",no_argument,NULL,'n'}, {"threads",required_argument,NULL,9}, {"output-file",required_argument,NULL,'o'}, {"output",required_argument,NULL,'o'}, {NULL, 0, NULL, 0} }; char *tmp; while ((c = getopt_long(argc, argv, "ctfm:snao:", loptions, NULL)) >= 0) { switch (c) { case 'c': tbi = 0; break; case 't': tbi = 1; min_shift = 0; break; case 'f': force = 1; break; case 'm': min_shift = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --min-shift %s\n", optarg); break; case 's': stats |= per_contig; break; case 'n': stats |= total; break; case 'a': stats |= all_contigs; break; case 9: n_threads = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --threads %s\n", optarg); break; case 'o': outfn = optarg; break; default: usage(); } } if (!min_shift) tbi = 1; if (stats > total) { fprintf(stderr, "[E::%s] expected only one of --stats or --nrecords options\n", __func__); return 1; } if (tbi && min_shift>0) { fprintf(stderr, "[E::%s] min-shift option only expected for CSI indices \n", __func__); return 1; } if (min_shift < 0 || min_shift > 30) { fprintf(stderr, "[E::%s] expected min_shift in range [0,30] (%d)\n", __func__, min_shift); return 1; } char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(); } else fname = argv[optind]; if (stats) return vcf_index_stats(fname, stats); kstring_t idx_fname = {0,0,0}; if (outfn) kputs(outfn,&idx_fname); else { if (!strcmp(fname, "-")) { fprintf(stderr, "[E::%s] must specify an output path for index file when reading VCF/BCF from stdin\n", __func__); return 1; } ksprintf(&idx_fname, "%s.%s", fname, tbi ? "tbi" : "csi"); } if (!force) { // Before complaining about existing index, check if the VCF file isn't newer. struct stat stat_tbi, stat_file; if ( stat(idx_fname.s, &stat_tbi)==0 ) { stat(fname, &stat_file); if ( stat_file.st_mtime <= stat_tbi.st_mtime ) { fprintf(stderr,"[E::%s] the index file exists. Please use '-f' to overwrite %s\n", __func__, idx_fname.s); free(idx_fname.s); return 1; } } // check for truncated files, allow only with -f BGZF *fp = bgzf_open(fname, "r"); if ( !fp ) error("index: failed to open %s\n", fname); if ( bgzf_compression(fp)!=2 ) error("index: the file is not BGZF compressed, cannot index: %s\n", fname); if ( bgzf_check_EOF(fp)!=1 ) error("index: the input is probably truncated, use -f to index anyway: %s\n", fname); if ( bgzf_close(fp)!=0 ) error("index: close failed: %s\n", fname); } int ret = bcf_index_build3(fname, idx_fname.s, min_shift, n_threads); free(idx_fname.s); if (ret != 0) { if (ret == -2) error("index: failed to open \"%s\"\n", fname); else if (ret == -3) error("index: \"%s\" is in a format that cannot be usefully indexed\n", fname); else error("index: failed to create index for \"%s\"\n", fname); } return 0; } bcftools-1.21/vcfisec.c000066400000000000000000000741341467060157400150610ustar00rootroot00000000000000/* vcfisec.c -- Create intersections, unions and complements of VCF files. Copyright (C) 2012-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #define OP_PLUS 1 #define OP_MINUS 2 #define OP_EQUAL 3 #define OP_VENN 4 #define OP_COMPLEMENT 5 #define OP_EXACT 6 // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { int isec_op, isec_n, *write, iwrite, nwrite, output_type, n_threads, clevel; int nflt, *flt_logic; filter_t **flt; char **flt_expr; bcf_srs_t *files; FILE *fh_log, *fh_sites; htsFile **fh_out; char **argv, *prefix, *output_fname, **fnames, *write_files, *targets_list, *regions_list; char *isec_exact, *file_list; int argc, record_cmd_line; char *index_fn; int write_index; } args_t; /** * mkdir_p() - create new directory for a file $fname * @fname: the file name to create the directory for, the part after last "/" is ignored */ void HTS_FORMAT(HTS_PRINTF_FMT, 1, 2) mkdir_p(const char *fmt, ...) { va_list ap; va_start(ap, fmt); int n = vsnprintf(NULL, 0, fmt, ap) + 2; va_end(ap); char *tmp = (char*)malloc(n); if (!tmp) error("Couldn't allocate space for path: %s\n", strerror(errno)); va_start(ap, fmt); vsnprintf(tmp, n, fmt, ap); va_end(ap); char *p = tmp+1; while (*p) { while (*p && *p!='/') p++; if ( !*p ) break; char ctmp = *p; *p = 0; int ret = mkdir(tmp,S_IRWXU | S_IRWXG | S_IROTH | S_IXOTH); if ( ret!=0 && errno!=EEXIST ) error("Error creating directory %s: %s\n", tmp,strerror(errno)); *p = ctmp; while ( *p && *p=='/' ) p++; } free(tmp); } /** * open_file() - open new file creating the file name using vsnprintf * @fname: if not NULL, on output will point to newly allocated fname string * @mode: if NULL, only the file name string will be created * @fmt: vsnprintf format and args * * Returns open file descriptor or NULL if mode is NULL. */ FILE * HTS_FORMAT(HTS_PRINTF_FMT, 3, 4) open_file(char **fname, const char *mode, const char *fmt, ...) { va_list ap; va_start(ap, fmt); int n = vsnprintf(NULL, 0, fmt, ap) + 2; va_end(ap); char *str = (char*)malloc(n); va_start(ap, fmt); vsnprintf(str, n, fmt, ap); va_end(ap); mkdir_p("%s", str); if ( !mode ) { if ( !fname ) error("Uh: expected fname or mode\n"); *fname = str; return NULL; } FILE *fp = fopen(str,mode); if ( fname ) *fname = str; else free(str); return fp; } void isec_vcf(args_t *args) { bcf_srs_t *files = args->files; kstring_t str = {0,0,0}; htsFile *out_fh = NULL; // When only one VCF is output, print VCF to stdout or -o file int out_std = 0; if ( args->nwrite==1 && !args->prefix ) out_std = 1; if ( args->targets_list && files->nreaders==1 ) out_std = 1; if ( out_std ) { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( out_fh == NULL ) error("Can't write to %s: %s\n", args->output_fname? args->output_fname : "standard output", strerror(errno)); if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); if (args->record_cmd_line) bcf_hdr_append_version(files->readers[args->iwrite].header,args->argc,args->argv,"bcftools_isec"); if ( bcf_hdr_write(out_fh, files->readers[args->iwrite].header)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname?args->output_fname:"standard output"); if ( init_index2(out_fh,files->readers[args->iwrite].header, args->output_fname,&args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n", args->output_fname?args->output_fname:"standard output"); } if ( !args->nwrite && !out_std && !args->prefix ) fprintf(stderr,"Note: -w option not given, printing list of sites...\n"); int n; while ( (n=bcf_sr_next_line(files)) ) { bcf_sr_t *reader = NULL; bcf1_t *line = NULL; int i, ret = 0; for (i=0; inreaders; i++) { if ( !bcf_sr_has_line(files,i) ) continue; if ( args->nflt && args->flt[i] ) { bcf1_t *rec = bcf_sr_get_line(files, i); int pass = filter_test(args->flt[i], rec, NULL); if ( args->flt_logic[i] & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { files->has_line[i] = 0; n--; continue; } } if ( !line ) { line = files->readers[i].buffer[0]; reader = &files->readers[i]; } ret |= 1<isec_op) { case OP_COMPLEMENT: if ( n!=1 || !bcf_sr_has_line(files,0) ) continue; break; case OP_EQUAL: if ( n != args->isec_n ) continue; break; case OP_PLUS: if ( n < args->isec_n ) continue; break; case OP_MINUS: if ( n > args->isec_n ) continue; break; case OP_EXACT: for (i=0; inreaders; i++) if ( files->has_line[i] != args->isec_exact[i] ) break; if ( inreaders ) continue; break; } if ( out_std ) { if ( bcf_sr_has_line(files,args->iwrite) && bcf_write1(out_fh, files->readers[args->iwrite].header, files->readers[args->iwrite].buffer[0])!=0 ) error("[%s] Error: cannot write to %s\n", __func__, args->output_fname ? args->output_fname : "standard output"); continue; } else if ( args->fh_sites ) { str.l = 0; kputs(reader->header->id[BCF_DT_CTG][line->rid].key, &str); kputc('\t', &str); kputw(line->pos+1, &str); kputc('\t', &str); if (line->n_allele > 0) kputs(line->d.allele[0], &str); else kputc('.', &str); kputc('\t', &str); if (line->n_allele > 1) kputs(line->d.allele[1], &str); else kputc('.', &str); for (i=2; in_allele; i++) { kputc(',', &str); kputs(line->d.allele[i], &str); } kputc('\t', &str); for (i=0; inreaders; i++) kputc(bcf_sr_has_line(files,i)?'1':'0', &str); kputc('\n', &str); if ( fwrite(str.s,sizeof(char),str.l,args->fh_sites)!=str.l ) error("[%s] Error: failed to write %d bytes to %s\n", __func__,(int)str.l,args->output_fname ? args->output_fname : "standard output"); } if ( args->prefix ) { if ( args->isec_op==OP_VENN && ret==3 ) { if ( !args->nwrite || args->write[0] ) { if ( bcf_write1(args->fh_out[2], bcf_sr_get_header(files,0), bcf_sr_get_line(files,0))!=0 ) error("[%s] Error: cannot write\n", __func__); } if ( !args->nwrite || args->write[1] ) { if ( bcf_write1(args->fh_out[3], bcf_sr_get_header(files,1), bcf_sr_get_line(files,1))!=0 ) error("[%s] Error: cannot write\n", __func__); } } else { for (i=0; inreaders; i++) { if ( !bcf_sr_has_line(files,i) ) continue; if ( args->write && !args->write[i] ) continue; if ( bcf_write1(args->fh_out[i], files->readers[i].header, files->readers[i].buffer[0])!=0 ) error("[%s] Error: cannot write\n", __func__); } } } } if ( str.s ) free(str.s); if ( out_fh ) { if ( args->write_index ) { if ( bcf_idx_save(out_fh)<0 ) { if ( hts_close(out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname? args->output_fname : "-"); } } static void add_filter(args_t *args, char *expr, int logic) { args->nflt++; args->flt_expr = (char**) realloc(args->flt_expr,sizeof(char*)*args->nflt); args->flt_logic = (int*) realloc(args->flt_logic,sizeof(int)*args->nflt); args->flt = (filter_t**) realloc(args->flt,sizeof(filter_t*)*args->nflt); if ( expr[0]=='-' && expr[1]==0 ) { args->flt_expr[args->nflt-1] = NULL; args->flt[args->nflt-1] = NULL; } else args->flt_expr[args->nflt-1] = expr; args->flt_logic[args->nflt-1] = logic; } static void destroy_data(args_t *args); static void init_data(args_t *args) { int i; if ( args->nflt ) { if ( args->nflt > 1 && args->nflt!=args->files->nreaders ) error("Error: expected either one -i/-e option or as many as there are input files\n"); if ( args->nflt < args->files->nreaders ) { if ( !args->flt_expr[0] ) error("Error: useless use of -i/-e\n"); args->nflt = args->files->nreaders; args->flt_expr = (char**) realloc(args->flt_expr,sizeof(char*)*args->nflt); args->flt_logic = (int*) realloc(args->flt_logic,sizeof(int)*args->nflt); args->flt = (filter_t**) realloc(args->flt,sizeof(filter_t*)*args->nflt); for (i=1; inflt; i++) { args->flt_expr[i] = args->flt_expr[0]; args->flt_logic[i] = args->flt_logic[0]; args->flt[i] = filter_init(args->files->readers[i].header,args->flt_expr[i]); } args->flt[0] = filter_init(args->files->readers[0].header,args->flt_expr[0]); } else { for (i=0; ifiles->nreaders; i++) { if ( !args->flt_expr[i] ) continue; args->flt[i] = filter_init(args->files->readers[i].header,args->flt_expr[i]); } } } if ( args->isec_op==OP_EXACT ) { if ( strlen(args->isec_exact)!=args->files->nreaders ) error("The number of files does not match the bitmask: %d vs %s\n", args->files->nreaders,args->isec_exact); for (i=0; ifiles->nreaders; i++) if ( args->isec_exact[i]!='0' && args->isec_exact[i]!='1' ) error("Unexpected bitmask: %s\n",args->isec_exact); for (i=0; ifiles->nreaders; i++) args->isec_exact[i] -= '0'; } // Which files to write: parse the string passed with -w char *p = args->write_files; while (p && *p) { if ( !args->write ) args->write = (int*) calloc(args->files->nreaders,sizeof(int)); if ( sscanf(p,"%d",&i)!=1 ) error("Could not parse --write %s\n", args->write_files); if ( i<=0 || i>args->files->nreaders ) error("The index is out of range: %d (-w %s)\n", i, args->write_files); args->write[i-1] = 1; args->iwrite = i-1; args->nwrite++; while (*p && *p!=',') p++; if ( *p==',' ) p++; } if ( args->nwrite>1 && !args->prefix ) error("Expected -p when multiple output files given: --write %s\n", args->write_files); if ( args->isec_op==OP_COMPLEMENT && args->nwrite ) { if ( args->nwrite>1 ) error("Multiple files to -w make no sense with -C\n"); if ( !args->write[0] ) error("Only -w1 makes sense with -C\n"); } if ( args->prefix ) { // Init output directory and create the readme file args->fh_log = open_file(NULL,"w","%s/README.txt", args->prefix); if ( !args->fh_log ) error("%s/README.txt: %s\n", args->prefix, strerror(errno)); fprintf(args->fh_log,"This file was produced by vcfisec.\n"); fprintf(args->fh_log,"The command line was:\tbcftools %s ", args->argv[0]); int i; for (i=1; iargc; i++) fprintf(args->fh_log," %s",args->argv[i]); fprintf(args->fh_log,"\n\nUsing the following file names:\n"); const char *suffix = "vcf"; if ( args->output_type & FT_BCF ) suffix = "bcf"; else if ( args->output_type & FT_GZ ) suffix = "vcf.gz"; // Open output files and write the legend if ( args->isec_op==OP_VENN ) { args->fh_out = (htsFile**) malloc(sizeof(htsFile*)*4); args->fnames = (char**) calloc(4,sizeof(char*)); #define OPEN_FILE(i,j) { \ open_file(&args->fnames[i], NULL, "%s/%04d.%s", args->prefix, i, suffix); \ char wmode[8]; \ set_wmode(wmode,args->output_type,args->fnames[i],args->clevel); \ args->fh_out[i] = hts_open(args->fnames[i], wmode); \ if ( !args->fh_out[i] ) error("Could not open %s\n", args->fnames[i]); \ if ( args->n_threads ) hts_set_threads(args->fh_out[i], args->n_threads); \ if (args->record_cmd_line) bcf_hdr_append_version(args->files->readers[j].header,args->argc,args->argv,"bcftools_isec"); \ if ( bcf_hdr_write(args->fh_out[i], args->files->readers[j].header)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->fnames[i]); \ } if ( !args->nwrite || args->write[0] ) { OPEN_FILE(0,0); fprintf(args->fh_log,"%s\tfor records private to\t%s\n", args->fnames[0], args->files->readers[0].fname); } if ( !args->nwrite || args->write[1] ) { OPEN_FILE(1,1); fprintf(args->fh_log,"%s\tfor records private to\t%s\n", args->fnames[1], args->files->readers[1].fname); } if ( !args->nwrite || args->write[0] ) { OPEN_FILE(2,0); fprintf(args->fh_log,"%s\tfor records from %s shared by both\t%s %s\n", args->fnames[2], args->files->readers[0].fname, args->files->readers[0].fname, args->files->readers[1].fname); } if ( !args->nwrite || args->write[1] ) { OPEN_FILE(3,1); fprintf(args->fh_log,"%s\tfor records from %s shared by both\t%s %s\n", args->fnames[3], args->files->readers[1].fname, args->files->readers[0].fname, args->files->readers[1].fname); } } else { // Init one output file for each reader args->fh_out = (htsFile**) calloc(args->files->nreaders, sizeof(htsFile*)); args->fnames = (char**) calloc(args->files->nreaders, sizeof(char*)); for (i=0; ifiles->nreaders; i++) { if ( args->write && !args->write[i] ) continue; if ( args->isec_op==OP_COMPLEMENT && i>0 ) break; OPEN_FILE(i,i); fprintf(args->fh_log,"%s\tfor stripped\t%s\n", args->fnames[i], args->files->readers[i].fname); } #undef OPEN_FILE } args->fh_sites = open_file(NULL, "w", "%s/sites.txt", args->prefix); if ( !args->fh_sites ) error("%s/sites.txt: %s\n", args->prefix, strerror(errno)); } else { if (args->output_fname) { args->fh_sites = fopen(args->output_fname, "w"); if ( args->fh_sites == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); } else args->fh_sites = stdout; } } static void destroy_data(args_t *args) { int i; if ( args->nflt ) { for (i=0; inflt; i++) { if ( !args->flt[i] ) continue; filter_destroy(args->flt[i]); } free(args->flt_expr); free(args->flt); free(args->flt_logic); } if ( args->prefix ) { fclose(args->fh_log); int n = args->isec_op==OP_VENN ? 4 : args->files->nreaders; for (i=0; ifnames[i] ) continue; if ( hts_close(args->fh_out[i])!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fnames[i]); int is_tbi = !args->write_index || (args->write_index&127) == HTS_FMT_TBI; if ( args->output_type==FT_VCF_GZ && is_tbi ) { tbx_conf_t conf = tbx_conf_vcf; tbx_index_build(args->fnames[i], -1, &conf); } else if ( args->output_type==FT_BCF_GZ || !is_tbi ) { if ( bcf_index_build(args->fnames[i],14) ) error("Could not index %s\n", args->fnames[i]); } free(args->fnames[i]); } free(args->fh_out); free(args->fnames); if ( args->fh_sites ) fclose(args->fh_sites); if ( args->write ) free(args->write); } } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Create intersections, unions and complements of VCF files.\n"); fprintf(stderr, "Usage: bcftools isec [options] [...]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -c, --collapse STRING Treat as identical records with , see man page for details [none]\n"); fprintf(stderr, " -C, --complement Output positions present only in the first file but missing in the others\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true\n"); fprintf(stderr, " -f, --apply-filters LIST Require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); fprintf(stderr, " -i, --include EXPR Include only sites for which the expression is true\n"); fprintf(stderr, " -l, --file-list FILE Read the input file names from the file\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -n, --nfiles [+-=~]INT Output positions present in this many (=), this many or more (+), this many or fewer (-), the exact (~) files\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " -p, --prefix DIR If given, subset each of the input files accordingly, see also -w\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " --threads INT Use multithreading with worker threads [0]\n"); fprintf(stderr, " -w, --write LIST List of files to write with -p given as 1-based indexes. By default, all files are written\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Examples:\n"); fprintf(stderr, " # Create intersection and complements of two sets saving the output in dir/*\n"); fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz -p dir\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Filter sites in A and B (but not in C) and create intersection\n"); fprintf(stderr, " bcftools isec -e'MAF<0.01' -i'dbSNP=1' -e - A.vcf.gz B.vcf.gz C.vcf.gz -p dir\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Extract and write records from A shared by both A and B using exact allele match\n"); fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz -p dir -n =2 -w 1\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Extract and write records from C found in A and C but not in B\n"); fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz C.vcf.gz -p dir -n~101 -w 3\n"); fprintf(stderr, "\n"); fprintf(stderr, " # Extract records private to A or B comparing by position only\n"); fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz -p dir -n -1 -c all\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfisec(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->files = bcf_sr_init(); args->argc = argc; args->argv = argv; args->output_fname = NULL; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->clevel = -1; int targets_is_file = 0, regions_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; static struct option loptions[] = { {"help",no_argument,NULL,'h'}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"collapse",required_argument,NULL,'c'}, {"complement",no_argument,NULL,'C'}, {"apply-filters",required_argument,NULL,'f'}, {"file-list",required_argument,NULL,'l'}, {"nfiles",required_argument,NULL,'n'}, {"prefix",required_argument,NULL,'p'}, {"write",required_argument,NULL,'w'}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,4}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,3}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "hc:r:R:p:n:w:t:T:Cf:o:O:i:e:l:W::",loptions,NULL)) >= 0) { switch (c) { case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'c': if ( !strcmp(optarg,"snps") ) args->files->collapse |= COLLAPSE_SNPS; else if ( !strcmp(optarg,"indels") ) args->files->collapse |= COLLAPSE_INDELS; else if ( !strcmp(optarg,"both") ) args->files->collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; else if ( !strcmp(optarg,"any") ) args->files->collapse |= COLLAPSE_ANY; else if ( !strcmp(optarg,"all") ) args->files->collapse |= COLLAPSE_ANY; else if ( !strcmp(optarg,"some") ) args->files->collapse |= COLLAPSE_SOME; else if ( !strcmp(optarg,"none") ) args->files->collapse = COLLAPSE_NONE; else error("The --collapse string \"%s\" not recognised.\n", optarg); break; case 'f': args->files->apply_filters = optarg; break; case 'C': if ( args->isec_op!=0 && args->isec_op!=OP_COMPLEMENT ) error("Error: either -C or -n should be given, not both.\n"); args->isec_op = OP_COMPLEMENT; break; case 'l': args->file_list = optarg; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'p': args->prefix = optarg; break; case 'w': if ( args->write_files ) error("The option -w accepts a list of indices and can be given only once\n"); args->write_files = optarg; break; case 'i': add_filter(args, optarg, FLT_INCLUDE); break; case 'e': add_filter(args, optarg, FLT_EXCLUDE); break; case 'n': { if ( args->isec_op!=0 && args->isec_op==OP_COMPLEMENT ) error("Error: either -C or -n should be given, not both.\n"); if ( args->isec_op!=0 ) error("Error: -n should be given only once.\n"); char *p = optarg; if ( *p=='-' ) { args->isec_op = OP_MINUS; p++; } else if ( *p=='+' ) { args->isec_op = OP_PLUS; p++; } else if ( *p=='=' ) { args->isec_op = OP_EQUAL; p++; } else if ( *p=='~' ) { args->isec_op = OP_EXACT; p++; } else if ( isdigit(*p) ) args->isec_op = OP_EQUAL; else error("Could not parse --nfiles %s\n", optarg); if ( args->isec_op == OP_EXACT ) args->isec_exact = p; else if ( sscanf(p,"%d",&args->isec_n)!=1 ) error("Could not parse --nfiles %s\n", optarg); } break; case 3 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } if ( argc-optind<1 && !args->file_list ) usage(); // no file given int nfiles = 0,i; char **files = NULL; if ( args->file_list ) { files = hts_readlines(args->file_list, &nfiles); if ( !files ) error("Failed to read from %s\n", args->file_list); } if ( optind0; i--) files[n+i-1] = files[n+i-2]; for (i=0; itargets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file,0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( nfiles==2 && !args->isec_op ) { args->isec_op = OP_VENN; if ( !args->prefix ) error("Expected the -p option\n"); } if ( !args->isec_op ) { args->isec_op = OP_PLUS; args->isec_n = 1; } args->files->require_index = 1; for (i=0; ifiles, files[i]) ) error("Failed to open %s: %s\n", files[i],bcf_sr_strerror(args->files->errnum)); free(files[i]); } free(files); init_data(args); isec_vcf(args); destroy_data(args); bcf_sr_destroy(args->files); free(args); return 0; } bcftools-1.21/vcfmerge.c000066400000000000000000004503411467060157400152330ustar00rootroot00000000000000/* vcfmerge.c -- Merge multiple VCF/BCF files to create one multi-sample file. Copyright (C) 2012-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "regidx.h" #include "vcmp.h" #define DBG 0 #define COLLAPSE_SNP_INS_DEL (1<<10) #include KHASH_MAP_INIT_STR(strdict, int) typedef khash_t(strdict) strdict_t; #define FLT_LOGIC_ADD 0 #define FLT_LOGIC_REMOVE 1 #define SKIP_DONE 1 // the record was processed #define SKIP_DIFF 2 // not compatible, merge later #define IS_VL_G(hdr,id) (bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_G) #define IS_VL_A(hdr,id) (bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_A) #define IS_VL_R(hdr,id) (bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_R) #define SWAP(type_t,a,b) { type_t tmp = (a); (a) = (b); (b) = tmp; } #define PL2PROB_MAX 1024 // Rules for merging FORMAT Number=A,G,R vectors with missing values #define MERGE_MISSING_DOT 0 // leave as is, i.e. use a missing value "." #define MERGE_MISSING_CONST 1 // use a constant value #define MERGE_MISSING_MAX 2 // use the existing maximum value typedef struct _missing_rule_t { char *hdr_tag; int type; float value; } missing_rule_t; // For merging INFO Number=A,G,R tags typedef struct { const char *hdr_tag; int type, nvals; int nbuf, mbuf; uint8_t *buf; } AGR_info_t; // Rules for merging arbitrary INFO tags typedef struct _info_rule_t { char *hdr_tag; void (*merger)(bcf_hdr_t *hdr, bcf1_t *line, struct _info_rule_t *rule); int type; // one of BCF_HT_* int block_size; // number of values in a block int type_size; // size of the corresponding BCF_HT_* type int nblocks; // number of blocks in nvals (the number of merged files) int nvals, mvals; // used and total size of vals array void *vals; // the info tag values } info_rule_t; typedef struct { bcf1_t *line; int end, active; // end: 0-based INFO/END } gvcf_aux_t; // Auxiliary merge data for selecting the right combination // of buffered records across multiple readers. maux1_t // corresponds to one buffered line. typedef struct { int skip; int *map; // mapping from input alleles to the array of output alleles (set by merge_alleles) int mmap; // size of map array (only buffer[i].n_allele is actually used) int als_differ; int var_types; // variant types in this record, shifted by <<1 to account for VCF_REF } maux1_t; // Buffered lines for a single reader typedef struct { int rid; // current rid int beg,end; // valid ranges in reader's buffer [beg,end). Maintained by maux_reset and gvcf_flush. int unkn_allele;// the index of the unknown allele (<*>, ) int cur; // current line or -1 if none int mrec; // allocated size of buf maux1_t *rec; // buffer to keep reader's lines bcf1_t **lines; // source buffer: either gvcf or readers' buffer int var_types; // reader's variant types in the active [beg,end] window } buffer_t; typedef struct { int n, pos, var_types; // number of readers; current position; variant types at this position across all available records int *als_types, // allele type of each output allele mals_types; char *chr; // current chromosome char **als, **out_als; // merged alleles (temp, may contain empty records) and merged alleles ready for output int nals, mals, nout_als, mout_als; // size of the output array int *cnt, ncnt; // number of records that refer to the alleles int *smpl_ploidy, *smpl_nGsize; // ploidy and derived number of values in Number=G tags, updated for each line (todo: cache for missing cases) const char **fmt_key;// temporary short-lived array to store output tag names bcf_fmt_t **fmt_map; // i-th output FORMAT field corresponds in j-th reader to i*nreader+j, first row is reserved for GT int nfmt_map; // number of rows in the fmt_map array int *agr_map, nagr_map, magr_map; // mapping between Number=AGR element indexes, from src idxs to dst file idxs void *tmp_arr; size_t ntmp_arr; buffer_t *buf; AGR_info_t *AGR_info; int nAGR_info, mAGR_info; bcf_srs_t *files; int gvcf_min, // min buffered gvcf END position (NB: gvcf_min is 1-based) or 0 if no active lines are present gvcf_break; // 0-based position of a next record which breaks a gVCF block gvcf_aux_t *gvcf; // buffer of gVCF lines, for each reader one line int nout_smpl; kstring_t *str; int32_t *laa; // localized alternate alleles given as input-based indexes in per-sample blocks of (args->local_alleles+1) values, 0 is always first int nlaa, laa_dirty; // number of LAA alleles actually used at this site, and was any L* added? int32_t *tmpi, *k2k; double *tmpd, *pl2prob; // mapping from phred-score likelihoods (PL) to probability int ntmpi, ntmpd, nk2k; } maux_t; typedef struct { vcmp_t *vcmp; maux_t *maux; regidx_t *regs; // apply regions only after the blocks are expanded regitr_t *regs_itr; int header_only, collapse, output_type, force_samples, force_single, merge_by_id, do_gvcf, filter_logic, missing_to_ref, no_index; char *header_fname, *output_fname, *regions_list, *info_rules, *file_list; faidx_t *gvcf_fai; info_rule_t *rules; int nrules; char *missing_rules_str; missing_rule_t *missing_rules; // lookup for -M, --missing-rules int nmissing_rules; strdict_t *tmph; kstring_t tmps; bcf_srs_t *files; bcf1_t *out_line; htsFile *out_fh; bcf_hdr_t *out_hdr; char **argv; int argc, n_threads, record_cmd_line, clevel; int local_alleles; // the value of -L option int keep_AC_AN; char *index_fn; int write_index; int trim_star_allele; // 0=don't trim; 1=trim at variant sites; 2=trim at all sites } args_t; static bcf1_t *maux_get_line(args_t *args, int i) { maux_t *ma = args->maux; int ibuf = ma->buf[i].cur; if ( ibuf >= 0 ) return ma->buf[i].lines[ibuf]; return NULL; } static void info_rules_merge_sum(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) { if ( !rule->nvals ) return; int i, j, ndim = rule->block_size; #define BRANCH(type_t,is_missing) { \ type_t *ptr = (type_t*) rule->vals; \ for (i=0; invals; i++) if ( is_missing ) ptr[i] = 0; \ for (i=1; inblocks; i++) \ { \ for (j=0; jtype) { case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing); break; case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i])); break; default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); } #undef BRANCH bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); } static void info_rules_merge_avg(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) { if ( !rule->nvals ) return; int i, j, ndim = rule->block_size; #define BRANCH(type_t,is_missing) { \ type_t *ptr = (type_t*) rule->vals; \ for (i=0; invals; i++) if ( is_missing ) ptr[i] = 0; \ for (j=0; jnblocks; i++) sum += ptr[j+i*ndim]; \ ptr[j] = sum / rule->nblocks; \ } \ } switch (rule->type) { case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing); break; case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i])); break; default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); } #undef BRANCH bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); } static void info_rules_merge_min(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) { if ( !rule->nvals ) return; int i, j, ndim = rule->block_size; #define BRANCH(type_t,is_missing,set_missing,huge_val) { \ type_t *ptr = (type_t*) rule->vals; \ for (i=0; invals; i++) if ( is_missing ) ptr[i] = huge_val; \ for (i=1; inblocks; i++) \ { \ for (j=0; j ptr[j+i*ndim] ) ptr[j] = ptr[j+i*ndim]; \ } \ for (i=0; invals; i++) if ( ptr[i]==huge_val ) set_missing; \ } switch (rule->type) { case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing, ptr[i]=bcf_int32_missing, INT32_MAX); break; case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i]), bcf_float_set_missing(ptr[i]), HUGE_VAL); break; default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); } #undef BRANCH bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); } static void info_rules_merge_max(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) { if ( !rule->nvals ) return; int i, j, ndim = rule->block_size; #define BRANCH(type_t,is_missing,set_missing,huge_val) { \ type_t *ptr = (type_t*) rule->vals; \ for (i=0; invals; i++) if ( is_missing ) ptr[i] = huge_val; \ for (i=1; inblocks; i++) \ { \ for (j=0; jnvals; i++) if ( ptr[i]==huge_val ) set_missing; \ } switch (rule->type) { case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing, ptr[i]=bcf_int32_missing, INT32_MIN); break; case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i]), bcf_float_set_missing(ptr[i]), -HUGE_VAL); break; default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); } #undef BRANCH bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); } static void info_rules_merge_join(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) { if ( !rule->nvals ) return; if ( rule->type==BCF_HT_STR ) { ((char*)rule->vals)[rule->nvals] = 0; bcf_update_info_string(hdr,line,rule->hdr_tag,rule->vals); } else { int isrc, idst = 0; #define BRANCH(type_t,is_missing,is_vector_end) { \ type_t *ptr = (type_t*) rule->vals; \ for (isrc=0; isrcnvals; isrc++) \ { \ if ( is_vector_end ) break; \ if ( is_missing ) continue; \ if ( idst!=isrc ) ptr[idst] = ptr[isrc]; \ idst++; \ } \ } switch (rule->type) { case BCF_HT_INT: BRANCH(int32_t, ptr[isrc]==bcf_int32_missing, ptr[isrc]==bcf_int32_vector_end); break; case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[isrc]), bcf_float_is_vector_end(ptr[isrc])); break; default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); } #undef BRANCH rule->nvals = idst; bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,rule->nvals,rule->type); } } static int missing_rules_comp_key2(const void *a, const void *b) { missing_rule_t *rule1 = (missing_rule_t*) a; missing_rule_t *rule2 = (missing_rule_t*) b; return strcmp(rule1->hdr_tag, rule2->hdr_tag); } static int missing_rules_comp_key(const void *a, const void *b) { char *key = (char*) a; missing_rule_t *rule = (missing_rule_t*) b; return strcmp(key, rule->hdr_tag); } static void missing_rules_init(args_t *args) { kstring_t str = {0,0,0}; if ( args->missing_rules_str ) { if ( !strcmp("-",args->missing_rules_str) ) kputs("PL:.,AD:.",&str); else kputs(args->missing_rules_str,&str); } else if ( args->do_gvcf ) kputs("PL:max,AD:0",&str); else return; args->nmissing_rules = 1; char *ss = str.s, *tmp = ss; int n = 0; while ( *ss ) { if ( *ss==':' ) { *ss = 0; n++; if ( n%2==0 ) error("Could not parse --missing-rules: \"%s\"\n", args->missing_rules_str); } else if ( *ss==',' ) { *ss = 0; args->nmissing_rules++; n++; if ( n%2==1 ) error("Could not parse --missing-rules: \"%s\"\n", args->missing_rules_str); } ss++; } if ( n%2==0 ) error("Could not parse --missing-rules: \"%s\"\n", args->missing_rules_str); args->missing_rules = (missing_rule_t*) calloc(args->nmissing_rules,sizeof(missing_rule_t)); n = args->nmissing_rules; args->nmissing_rules = 0; ss = tmp; while ( args->nmissing_rules < n ) { missing_rule_t *rule = &args->missing_rules[args->nmissing_rules]; rule->hdr_tag = strdup(ss); int id = bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, rule->hdr_tag); if ( !bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_FMT,id) ) { if ( args->missing_rules_str ) error("The FORMAT tag is not defined in the header: \"%s\"\n", rule->hdr_tag); free(rule->hdr_tag); n--; ss = strchr(ss, '\0'); ss++; if ( !*ss ) error("Could not parse --missing-rules, missing logic of \"%s\"\n", rule->hdr_tag); ss = strchr(ss, '\0'); ss++; continue; } ss = strchr(ss, '\0'); ss++; if ( !*ss ) error("Could not parse --missing-rules, missing logic of \"%s\"\n", rule->hdr_tag); if ( !strcasecmp(ss,".") ) rule->type = MERGE_MISSING_DOT; else if ( !strcasecmp(ss,"max") ) rule->type = MERGE_MISSING_MAX; else { char *tmp = ss; rule->value = strtod(ss, &tmp); if ( *tmp ) error("Could not parse --missing-rules: \"%s\"\n", args->missing_rules_str); rule->type = MERGE_MISSING_CONST; } ss = strchr(ss, '\0'); ss++; args->nmissing_rules++; } qsort(args->missing_rules, args->nmissing_rules, sizeof(*args->missing_rules), missing_rules_comp_key2); free(str.s); } static void missing_rules_destroy(args_t *args) { int i; for (i=0; inmissing_rules; i++) { missing_rule_t *rule = &args->missing_rules[i]; free(rule->hdr_tag); } free(args->missing_rules); } static int info_rules_comp_key2(const void *a, const void *b) { info_rule_t *rule1 = (info_rule_t*) a; info_rule_t *rule2 = (info_rule_t*) b; return strcmp(rule1->hdr_tag, rule2->hdr_tag); } static int info_rules_comp_key(const void *a, const void *b) { char *key = (char*) a; info_rule_t *rule = (info_rule_t*) b; return strcmp(key, rule->hdr_tag); } static void info_rules_init(args_t *args) { if ( args->info_rules && !strcmp("-",args->info_rules) ) return; kstring_t str = {0,0,0}; if ( !args->info_rules ) { if ( bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "DP")) ) kputs("DP:sum",&str); if ( bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "DP4")) ) { if ( str.l ) kputc(',',&str); kputs("DP4:sum",&str); } if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "QS")) ) { if ( str.l ) kputc(',',&str); kputs("QS:sum",&str); } if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "MIN_DP")) ) { if ( str.l ) kputc(',',&str); kputs("MIN_DP:min",&str); } if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "MinDP")) ) { if ( str.l ) kputc(',',&str); kputs("MinDP:min",&str); } if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "I16")) ) { if ( str.l ) kputc(',',&str); kputs("I16:sum",&str); } if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "IDV")) ) { if ( str.l ) kputc(',',&str); kputs("IDV:max",&str); } if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "IMF")) ) { if ( str.l ) kputc(',',&str); kputs("IMF:max",&str); } if ( !bcf_hdr_nsamples(args->out_hdr) ) { if ( bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "AN")) ) { if ( str.l ) kputc(',',&str); kputs("AN:sum",&str); } if ( bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "AC")) ) { if ( str.l ) kputc(',',&str); kputs("AC:sum",&str); } } if ( !str.l ) return; args->info_rules = str.s; } args->nrules = 1; char *ss = strdup(args->info_rules), *tmp = ss; int n = 0; while ( *ss ) { if ( *ss==':' ) { *ss = 0; n++; if ( n%2==0 ) error("Could not parse INFO rules: \"%s\"\n", args->info_rules); } else if ( *ss==',' ) { *ss = 0; args->nrules++; n++; if ( n%2==1 ) error("Could not parse INFO rules: \"%s\"\n", args->info_rules); } ss++; } if ( n%2==0 ) error("Could not parse INFO rules: \"%s\"\n", args->info_rules); args->rules = (info_rule_t*) calloc(args->nrules,sizeof(info_rule_t)); n = 0; ss = tmp; while ( n < args->nrules ) { info_rule_t *rule = &args->rules[n]; rule->hdr_tag = strdup(ss); int id = bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, rule->hdr_tag); if ( !bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,id) ) error("The INFO tag is not defined in the header: \"%s\"\n", rule->hdr_tag); rule->type = bcf_hdr_id2type(args->out_hdr,BCF_HL_INFO,id); if ( rule->type==BCF_HT_INT ) rule->type_size = sizeof(int32_t); else if ( rule->type==BCF_HT_REAL ) rule->type_size = sizeof(float); else if ( rule->type==BCF_HT_STR ) rule->type_size = sizeof(char); else error("The INFO rule \"%s\" is not supported; the tag \"%s\" type is %d\n", ss,rule->hdr_tag,rule->type); if ( !strcmp(rule->hdr_tag,"AC") || !strcmp(rule->hdr_tag,"AN") ) args->keep_AC_AN = 1; ss = strchr(ss, '\0'); ss++; if ( !*ss ) error("Could not parse INFO rules, missing logic of \"%s\"\n", rule->hdr_tag); int is_join = 0; if ( !strcasecmp(ss,"sum") ) rule->merger = info_rules_merge_sum; else if ( !strcasecmp(ss,"avg") ) rule->merger = info_rules_merge_avg; else if ( !strcasecmp(ss,"min") ) rule->merger = info_rules_merge_min; else if ( !strcasecmp(ss,"max") ) rule->merger = info_rules_merge_max; else if ( !strcasecmp(ss,"join") ) { rule->merger = info_rules_merge_join; is_join = 1; } else error("The rule logic \"%s\" not recognised\n", ss); if ( !is_join && rule->type==BCF_HT_STR ) error("Numeric operation \"%s\" requested on non-numeric field: %s\n", ss, rule->hdr_tag); if ( bcf_hdr_id2number(args->out_hdr,BCF_HL_INFO,id)==0xfffff ) { int is_agr = ( bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)==BCF_VL_A || bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)==BCF_VL_G || bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)==BCF_VL_R ) ? 1 : 0; if ( is_join && bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)!=BCF_VL_VAR ) { bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->out_hdr, BCF_HL_INFO, "ID", rule->hdr_tag, NULL); hrec = bcf_hrec_dup(hrec); int i = bcf_hrec_find_key(hrec, "Number"); if ( i<0 ) error("Uh, could not find the entry Number in the header record of %s\n",rule->hdr_tag); free(hrec->vals[i]); hrec->vals[i] = strdup("."); bcf_hdr_remove(args->out_hdr,BCF_HL_INFO, rule->hdr_tag); bcf_hdr_add_hrec(args->out_hdr, hrec); } if ( !is_join && !is_agr ) error("Only fixed-length vectors are supported with -i %s:%s\n", ss, rule->hdr_tag); } ss = strchr(ss, '\0'); ss++; n++; } free(str.s); free(tmp); qsort(args->rules, args->nrules, sizeof(*args->rules), info_rules_comp_key2); } static void info_rules_destroy(args_t *args) { int i; for (i=0; inrules; i++) { info_rule_t *rule = &args->rules[i]; free(rule->hdr_tag); free(rule->vals); } free(args->rules); } static void info_rules_reset(args_t *args) { int i; for (i=0; inrules; i++) args->rules[i].nblocks = args->rules[i].nvals = args->rules[i].block_size = 0; } static int info_rules_add_values(args_t *args, bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule, maux1_t *als, int var_len) { int msize = args->maux->ntmp_arr / rule->type_size; int ret = bcf_get_info_values(hdr, line, rule->hdr_tag, &args->maux->tmp_arr, &msize, rule->type); if ( ret<=0 ) error("FIXME: error parsing %s at %s:%"PRId64" .. %d\n", rule->hdr_tag,bcf_seqname(hdr,line),(int64_t) line->pos+1,ret); args->maux->ntmp_arr = msize * rule->type_size; rule->nblocks++; if ( rule->type==BCF_HT_STR ) { int need_comma = rule->nblocks==1 ? 0 : 1; hts_expand(char,rule->nvals+ret+need_comma+1,rule->mvals,rule->vals); // 1 for null-termination char *tmp = (char*) rule->vals + rule->nvals; if ( rule->nvals>0 ) { *tmp = ','; tmp++; } strncpy(tmp,(char*)args->maux->tmp_arr,ret); rule->nvals += ret + need_comma; return 1; } int i, j; if ( var_len==BCF_VL_A ) { if ( ret!=line->n_allele-1 ) error("Wrong number of %s fields at %s:%"PRId64"\n",rule->hdr_tag,bcf_seqname(hdr,line),(int64_t) line->pos+1); args->maux->nagr_map = ret; hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); // create mapping from source file ALT indexes to dst file indexes for (i=0; imaux->agr_map[i] = als->map[i+1] - 1; rule->block_size = args->maux->nout_als - 1; } else if ( var_len==BCF_VL_R ) { if ( ret!=line->n_allele ) error("Wrong number of %s fields at %s:%"PRId64"\n",rule->hdr_tag,bcf_seqname(hdr,line),(int64_t) line->pos+1); args->maux->nagr_map = ret; hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); for (i=0; imaux->agr_map[i] = als->map[i]; rule->block_size = args->maux->nout_als; } else if ( var_len==BCF_VL_G ) { args->maux->nagr_map = bcf_alleles2gt(line->n_allele-1,line->n_allele-1)+1; if ( ret!=line->n_allele && ret!=args->maux->nagr_map ) error("Wrong number of %s fields at %s:%"PRId64"\n",rule->hdr_tag,bcf_seqname(hdr,line),(int64_t) line->pos+1); if ( ret==line->n_allele ) // haploid { args->maux->nagr_map = line->n_allele; hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); for (i=0; imaux->agr_map[i] = als->map[i]; rule->block_size = args->maux->nout_als; } else { hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); int k_src = 0; for (i=0; in_allele; i++) { for (j=0; j<=i; j++) { args->maux->agr_map[k_src] = bcf_alleles2gt(als->map[i],als->map[j]); k_src++; } } rule->block_size = bcf_alleles2gt(args->maux->nout_als-1,args->maux->nout_als-1)+1; } } else { if ( rule->nblocks>1 && ret!=rule->block_size ) error("Mismatch in number of values for INFO/%s at %s:%"PRId64"\n", rule->hdr_tag,bcf_seqname(hdr,line),(int64_t) line->pos+1); rule->block_size = ret; args->maux->nagr_map = 0; } #define BRANCH(src_type_t,dst_type_t,set_missing) { \ src_type_t *src = (src_type_t *) args->maux->tmp_arr; \ hts_expand0(dst_type_t,(rule->nvals+rule->block_size),rule->mvals,rule->vals); \ dst_type_t *dst = (dst_type_t *) rule->vals + rule->nvals; \ rule->nvals += rule->block_size; \ if ( !args->maux->nagr_map ) \ { \ for (i=0; iblock_size; i++) set_missing; \ for (i=0; imaux->agr_map[i]] = src[i]; \ } \ } switch (rule->type) { case BCF_HT_INT: BRANCH(int, int32_t, dst[i] = bcf_int32_missing); break; case BCF_HT_REAL: BRANCH(float, float, bcf_float_set_missing(dst[i])); break; default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); } #undef BRANCH return 1; } int bcf_hdr_sync(bcf_hdr_t *h); void merge_headers(bcf_hdr_t *hw, const bcf_hdr_t *hr, const char *clash_prefix, int force_samples) { // header lines hw = bcf_hdr_merge(hw, hr); // samples int i; for (i=0; isamples[i]; while ( bcf_hdr_id2int(hw, BCF_DT_SAMPLE, name)!=-1 ) { // there is a sample with the same name if ( !force_samples ) error("Error: Duplicate sample names (%s), use --force-samples to proceed anyway.\n", name); // Resolve conflicting samples names. For example, replace: // A + A with A,2:A // A,2:A + A with A,2:A,2:2:A int len = strlen(name) + strlen(clash_prefix) + 1; char *tmp = (char*) malloc(sizeof(char)*(len+1)); sprintf(tmp,"%s:%s",clash_prefix,name); free(rmme); rmme = name = tmp; } bcf_hdr_add_sample(hw,name); free(rmme); } } void debug_als(char **als, int nals) { int k; for (k=0; k=lens[j] ) done = 1; if ( als[j][lens[j]-i] != als[0][lens[0]-i] ) { done = 1; break; } } if ( done ) break; i++; } if ( i>1 ) { i--; als[0][lens[0]-i] = 0; for (j=1; j0, * 1->2, and 2->3. */ char **merge_alleles(char **a, int na, int *map, char **b, int *nb, int *mb) { // reference allele never changes map[0] = 0; int i,j; int rla = !a[0][1] ? 1 : strlen(a[0]); int rlb = !b[0][1] ? 1 : strlen(b[0]); // the most common case: same SNPs if ( na==2 && *nb==2 && rla==1 && rlb==1 && a[1][0]==b[1][0] && !a[1][1] && !b[1][1] ) { map[1] = 1; return b; } // Sanity check: reference prefixes must be identical if ( strncmp(a[0],b[0],rlarlb ) { for (i=0; i<*nb; i++) { if ( b[i][0]=='<' ) continue; // symbolic allele, do not modify if ( b[i][0]=='*' ) continue; // overlapping deletion (*), do not modify int l = strlen(b[i]); b[i] = (char*) realloc(b[i],l+rla-rlb+1); memcpy(b[i]+l,a[0]+rlb,rla-rlb+1); } } // now check if the $a alleles are present and if not add them for (i=1; irla && a[i][0]!='<' && a[i][0]!='*' ) // $a alleles need expanding and not a symbolic allele or * { int l = strlen(a[i]); ai = (char*) malloc(l+rlb-rla+1); memcpy(ai,a[i],l); memcpy(ai+l,b[0]+rla,rlb-rla+1); const_ai = 0; } else ai = a[i]; for (j=1; j<*nb; j++) if ( !strcasecmp(ai,b[j]) ) break; if ( j<*nb ) // $b already has the same allele { map[i] = j; if ( !const_ai ) free(ai); continue; } // new allele map[i] = *nb; b[*nb] = const_ai ? strdup(ai) : ai; (*nb)++; } return b; } maux_t *maux_init(args_t *args) { bcf_srs_t *files = args->files; maux_t *ma = (maux_t*) calloc(1,sizeof(maux_t)); ma->n = files->nreaders; ma->files = files; int i, n_smpl = 0; for (i=0; in; i++) n_smpl += bcf_hdr_nsamples(files->readers[i].header); ma->nout_smpl = n_smpl; assert( n_smpl==bcf_hdr_nsamples(args->out_hdr) ); if ( args->do_gvcf ) { ma->gvcf = (gvcf_aux_t*) calloc(ma->n,sizeof(gvcf_aux_t)); // -Walloc-size-larger-than gives a harmless warning caused by signed integer ma->n for (i=0; in; i++) ma->gvcf[i].line = bcf_init1(); } ma->smpl_ploidy = (int*) calloc(n_smpl,sizeof(int)); ma->smpl_nGsize = (int*) malloc(n_smpl*sizeof(int)); ma->buf = (buffer_t*) calloc(ma->n,sizeof(buffer_t)); for (i=0; in; i++) ma->buf[i].rid = -1; ma->str = (kstring_t*) calloc(n_smpl,sizeof(kstring_t)); if ( args->local_alleles ) { ma->laa = (int32_t*)malloc(sizeof(*ma->laa)*ma->nout_smpl*(1+args->local_alleles)); ma->pl2prob = (double*)malloc(PL2PROB_MAX*sizeof(*ma->pl2prob)); for (i=0; ipl2prob[i] = pow(10,-0.1*i); } return ma; } void maux_destroy(maux_t *ma) { int i,j; for (i=0; inout_smpl; i++) free(ma->str[i].s); free(ma->str); free(ma->als_types); for (i=0; imals; i++) { free(ma->als[i]); ma->als[i] = NULL; } for (i=0; in; i++) // for each reader { for (j=0; jbuf[i].mrec; j++) // for each buffered line free(ma->buf[i].rec[j].map); free(ma->buf[i].rec); } free(ma->buf); if ( ma->gvcf ) { for (i=0; in; i++) bcf_destroy(ma->gvcf[i].line); free(ma->gvcf); } for (i=0; imAGR_info; i++) free(ma->AGR_info[i].buf); free(ma->agr_map); free(ma->AGR_info); if (ma->ntmp_arr) free(ma->tmp_arr); if (ma->nfmt_map) free(ma->fmt_map); free(ma->fmt_key); // ma->inf freed in bcf_destroy1 for (i=0; imals; i++) free(ma->als[i]); if (ma->mout_als) free(ma->out_als); free(ma->als); free(ma->cnt); free(ma->smpl_ploidy); free(ma->smpl_nGsize); free(ma->chr); free(ma->laa); free(ma->tmpi); free(ma->k2k); free(ma->tmpd); free(ma->pl2prob); free(ma); } void maux_expand1(buffer_t *buf, int size) { if ( buf->mrec < size ) { hts_expand0(maux1_t,size,buf->mrec,buf->rec); buf->mrec = size; } } void maux_reset(maux_t *ma, int *rid_tab) { int i,j; for (i=0; in; i++) maux_expand1(&ma->buf[i],ma->files->readers[i].nbuffer+1); for (i=0; imals; i++) { free(ma->als[i]); ma->als[i] = NULL; } const char *chr = NULL; ma->nals = 0; ma->pos = -1; for (i=0; in; i++) { if ( !bcf_sr_has_line(ma->files,i) ) continue; bcf1_t *line = bcf_sr_get_line(ma->files,i); bcf_hdr_t *hdr = bcf_sr_get_header(ma->files,i); chr = bcf_seqname(hdr,line); ma->pos = line->pos; break; } int new_chr = 0; if ( chr && (!ma->chr || strcmp(ma->chr,chr)) ) { free(ma->chr); ma->chr = strdup(chr); new_chr = 1; } for (i=0; in; i++) { bcf_hdr_t *hdr = bcf_sr_get_header(ma->files,i); if (new_chr) rid_tab[i] = bcf_hdr_name2id(hdr,chr); ma->buf[i].rid = rid_tab[i]; ma->buf[i].beg = bcf_sr_has_line(ma->files,i) ? 0 : 1; for (j=ma->buf[i].beg; j<=ma->files->readers[i].nbuffer; j++) { ma->buf[i].rec[j].skip = 0; ma->buf[i].rec[j].var_types = 0; bcf1_t *line = ma->files->readers[i].buffer[j]; if ( line->rid!=ma->buf[i].rid || line->pos!=ma->pos ) break; } ma->buf[i].end = j; ma->buf[i].cur = -1; if ( ma->buf[i].beg < ma->buf[i].end ) { ma->buf[i].lines = ma->files->readers[i].buffer; if ( ma->gvcf ) ma->gvcf[i].active = 0; // gvcf block cannot overlap with the next record } if ( new_chr && ma->gvcf ) ma->gvcf[i].active = 0; // make sure to close active gvcf block on new chr } } void maux_debug(maux_t *ma, int ir, int ib) { printf("[%d,%d]\t", ir,ib); int i; for (i=0; inals; i++) { printf(" %s [%d]", ma->als[i], ma->cnt[i]); } printf("\n"); } void merge_chrom2qual(args_t *args, bcf1_t *out) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; int i, ret; khiter_t kitr; strdict_t *tmph = args->tmph; kh_clear(strdict, tmph); kstring_t *tmps = &args->tmps; tmps->l = 0; maux_t *ma = args->maux; int *al_idxs = (int*) calloc(ma->nals,sizeof(int)); bcf_float_set_missing(out->qual); // CHROM, POS, ID, QUAL out->pos = -1; for (i=0; inreaders; i++) { bcf1_t *line = maux_get_line(args, i); if ( !line ) continue; bcf_unpack(line, BCF_UN_ALL); bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; // not all maux alleles are always used, mark the ones we'll need int j; for (j=1; jn_allele; j++) { int irec = ma->buf[i].cur; al_idxs[ ma->buf[i].rec[irec].map[j] ] = 1; } // position if ( out->pos==-1 ) { const char *chr = hdr->id[BCF_DT_CTG][line->rid].key; out->rid = bcf_hdr_name2id(out_hdr, chr); if ( strcmp(chr,out_hdr->id[BCF_DT_CTG][out->rid].key) ) error("Uh\n"); out->pos = line->pos; } // ID if ( line->d.id[0]!='.' || line->d.id[1] ) { kitr = kh_get(strdict, tmph, line->d.id); if ( kitr == kh_end(tmph) ) { if ( tmps->l ) kputc(';', tmps); kputs(line->d.id, tmps); kh_put(strdict, tmph, line->d.id, &ret); } } // set QUAL to the max qual value. Not exactly correct, but good enough for now if ( !bcf_float_is_missing(line->qual) ) { if ( bcf_float_is_missing(out->qual) || out->qual < line->qual ) out->qual = line->qual; } } // set ID if ( !tmps->l ) kputs(".", tmps); bcf_update_id(out_hdr, out, tmps->s); // set alleles ma->nout_als = 0; for (i=1; inals; i++) { if ( !al_idxs[i] ) continue; ma->nout_als++; // Adjust the indexes, the allele map could be created for multiple collapsed records, // some of which might be unused for this output line int ir, j; for (ir=0; irnreaders; ir++) { ma->buf[ir].unkn_allele = 0; bcf1_t *line = maux_get_line(args,ir); if ( !line ) continue; for (j=1; jn_allele; j++) { int irec = ma->buf[ir].cur; if ( ma->buf[ir].rec[irec].map[j]==i ) ma->buf[ir].rec[irec].map[j] = ma->nout_als; if ( bcf_has_variant_type(line,j,VCF_REF) && line->d.allele[j][0]=='<' ) ma->buf[ir].unkn_allele = j; } } } // Expand the arrays and realloc the alleles string. Note that all alleles are in a single allocated block. ma->nout_als++; hts_expand0(char*, ma->nout_als, ma->mout_als, ma->out_als); int k = 0; for (i=0; inals; i++) if ( i==0 || al_idxs[i] ) ma->out_als[k++] = strdup(ma->als[i]); if ( k!=ma->nout_als ) error("Error: could not merge alleles at %s:%"PRId64", sanity check failed: %d!=%d\n",bcf_seqname(out_hdr,out),out->pos+1,k,ma->nout_als); normalize_alleles(ma->out_als, ma->nout_als); bcf_update_alleles(out_hdr, out, (const char**) ma->out_als, ma->nout_als); free(al_idxs); for (i=0; inout_als; i++) free(ma->out_als[i]); } void merge_filter(args_t *args, bcf1_t *out) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; int i, ret; if ( args->filter_logic == FLT_LOGIC_REMOVE ) { for (i=0; inreaders; i++) { bcf1_t *line = maux_get_line(args, i); if ( !line ) continue; bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; if ( bcf_has_filter(hdr, line, "PASS") ) break; } if ( inreaders ) { int flt_id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, "PASS"); bcf_add_filter(out_hdr, out, flt_id); return; } } khiter_t kitr; strdict_t *tmph = args->tmph; kh_clear(strdict, tmph); out->d.n_flt = 0; for (i=0; inreaders; i++) { bcf1_t *line = maux_get_line(args, i); if ( !line ) continue; bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; int k; for (k=0; kd.n_flt; k++) { const char *flt = hdr->id[BCF_DT_ID][line->d.flt[k]].key; kitr = kh_get(strdict, tmph, flt); if ( kitr == kh_end(tmph) ) { int id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, flt); if ( id==-1 ) error("Error: The filter is not defined in the header: %s\n", flt); hts_expand(int,out->d.n_flt+1,out->d.m_flt,out->d.flt); out->d.flt[out->d.n_flt] = id; out->d.n_flt++; kh_put(strdict, tmph, flt, &ret); } } } // Check if PASS is not mixed with other filters if ( out->d.n_flt>1 ) { int id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, "PASS"); for (i=0; id.n_flt; i++) if ( out->d.flt[i]==id ) break; if ( id.n_flt ) { out->d.n_flt--; for (; id.n_flt; i++) out->d.flt[i] = out->d.flt[i+1]; } } } static void bcf_info_set_id(bcf1_t *line, bcf_info_t *info, int id, kstring_t *tmp_str) { uint8_t *ptr = info->vptr - info->vptr_off; bcf_dec_typed_int1(ptr, &ptr); tmp_str->l = 0; bcf_enc_int1(tmp_str, id); if ( tmp_str->l == ptr - info->vptr + info->vptr_off ) { // the new id is represented with the same number of bytes memcpy(info->vptr - info->vptr_off, tmp_str->s, tmp_str->l); return; } kputsn_(ptr, info->vptr - ptr, tmp_str); info->vptr_off = tmp_str->l; kputsn_(info->vptr, info->len << bcf_type_shift[info->type], tmp_str); info->vptr = (uint8_t*) tmp_str->s + info->vptr_off; tmp_str->s = NULL; tmp_str->m = 0; tmp_str->l = 0; } /* * copy_string_field() - copy a comma-separated field * @param src: source string * @param isrc: index of the field to copy * @param src_len: length of source string (excluding the terminating \0) * @param dst: destination kstring (must be initialized with missing values, e.g. as ".") * @param idst: index of the destination field */ int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst) { int ith_src = 0, start_src = 0; // i-th field in src string while ( ith_srcl ) { if ( dst->s[start_dst]==',' ) { ith_dst++; } start_dst++; } if ( ith_dst!=idst ) return -2; int end_dst = start_dst; while ( end_dstl && dst->s[end_dst]!=',' ) end_dst++; if ( end_dst - start_dst>1 || dst->s[start_dst]!='.' ) return 0; // do not overwrite non-empty values // Now start_dst and end_dst are indexes to the destination memory area // which needs to be replaced with nsrc_cpy // source bytes, end_dst points just after. int ndst_shift = nsrc_cpy - (end_dst - start_dst); int ndst_move = dst->l - end_dst + 1; // how many bytes must be moved (including \0) if ( ndst_shift ) { ks_resize(dst, dst->l + ndst_shift + 1); // plus \0 memmove(dst->s+end_dst+ndst_shift, dst->s+end_dst, ndst_move); } memcpy(dst->s+start_dst, src+start_src, nsrc_cpy); dst->l += ndst_shift; return 0; } static void merge_AGR_info_tag(bcf_hdr_t *hdr, bcf1_t *line, bcf_info_t *info, int len, maux1_t *als, AGR_info_t *agr) { int i; if ( !agr->nbuf ) { if ( info->type==BCF_BT_INT8 || info->type==BCF_BT_INT16 || info->type==BCF_BT_INT32 || info->type==BCF_BT_FLOAT ) { agr->nbuf = 4 * agr->nvals; hts_expand(uint8_t,agr->nbuf,agr->mbuf,agr->buf); if ( info->type!=BCF_BT_FLOAT ) { int32_t *tmp = (int32_t*) agr->buf; for (i=0; invals; i++) tmp[i] = bcf_int32_missing; } else { float *tmp = (float*) agr->buf; for (i=0; invals; i++) bcf_float_set_missing(tmp[i]); } } else if ( info->type==BCF_BT_CHAR ) { kstring_t tmp; tmp.l = 0; tmp.m = agr->mbuf; tmp.s = (char*)agr->buf; kputc('.',&tmp); for (i=1; invals; i++) kputs(",.",&tmp); agr->mbuf = tmp.m; agr->nbuf = tmp.l; agr->buf = (uint8_t*)tmp.s; } else error("Not ready for type [%d]: %s at %"PRId64"\n", info->type,agr->hdr_tag,(int64_t) line->pos+1); } if ( info->type==BCF_BT_INT8 || info->type==BCF_BT_INT16 || info->type==BCF_BT_INT32 || info->type==BCF_BT_FLOAT ) { if ( len==BCF_VL_A || len==BCF_VL_R ) { int ifrom = len==BCF_VL_A ? 1 : 0; #define BRANCH(type_t, convert, is_missing, is_vector_end, out_type_t) { \ uint8_t *src = info->vptr; \ out_type_t *tgt = (out_type_t *) agr->buf; \ int iori, inew; \ for (iori=ifrom; iorin_allele; iori++, src += sizeof(type_t)) \ { \ type_t val = convert(src); \ if ( is_vector_end ) break; \ if ( is_missing ) continue; \ inew = als->map[iori] - ifrom; \ tgt[inew] = val; \ } \ } switch (info->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, int); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, int); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, val==bcf_int32_missing, val==bcf_int32_vector_end, int); break; case BCF_BT_FLOAT: BRANCH(float, le_to_float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), float); break; default: fprintf(stderr,"TODO: %s:%d .. info->type=%d\n", __FILE__,__LINE__, info->type); exit(1); } #undef BRANCH } else { #define BRANCH(type_t, convert, is_missing, is_vector_end, out_type_t) { \ uint8_t *src = info->vptr; \ out_type_t *tgt = (out_type_t *) agr->buf; \ int iori,jori, inew,jnew; \ for (iori=0; iorin_allele; iori++) \ { \ inew = als->map[iori]; \ for (jori=0; jori<=iori; jori++) \ { \ jnew = als->map[jori]; \ int kori = iori*(iori+1)/2 + jori; \ type_t val = convert(&src[kori * sizeof(type_t)]); \ if ( is_vector_end ) break; \ if ( is_missing ) continue; \ int knew = inew>jnew ? inew*(inew+1)/2 + jnew : jnew*(jnew+1)/2 + inew; \ tgt[knew] = val; \ } \ if ( jori<=iori ) break; \ } \ } switch (info->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, int); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, int); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, val==bcf_int32_missing, val==bcf_int32_vector_end, int); break; case BCF_BT_FLOAT: BRANCH(float, le_to_float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), float); break; default: fprintf(stderr,"TODO: %s:%d .. info->type=%d\n", __FILE__,__LINE__, info->type); exit(1); } #undef BRANCH } } else { kstring_t tmp; tmp.l = agr->nbuf; tmp.m = agr->mbuf; tmp.s = (char*)agr->buf; if ( len==BCF_VL_A || len==BCF_VL_R ) { int iori, ifrom = len==BCF_VL_A ? 1 : 0; for (iori=ifrom; iorin_allele; iori++) { int ret = copy_string_field((char*)info->vptr, iori-ifrom, info->len, &tmp, als->map[iori]-ifrom); if ( ret ) error("Error at %s:%"PRId64": wrong number of fields in %s?\n", bcf_seqname(hdr,line),(int64_t) line->pos+1,agr->hdr_tag); } } else { int iori,jori, inew,jnew; for (iori=0; iorin_allele; iori++) { inew = als->map[iori]; for (jori=0; jori<=iori; jori++) { jnew = als->map[jori]; int kori = iori*(iori+1)/2 + jori; int knew = bcf_alleles2gt(inew,jnew); int ret = copy_string_field((char*)info->vptr, kori, info->len, &tmp, knew); if ( ret ) error("Error at %s:%"PRId64": wrong number of fields in %s?\n", bcf_seqname(hdr,line),(int64_t) line->pos+1,agr->hdr_tag); } } } agr->mbuf = tmp.m; agr->nbuf = tmp.l; agr->buf = (uint8_t*)tmp.s; } } void merge_info(args_t *args, bcf1_t *out) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; int i, j, ret; khiter_t kitr; strdict_t *tmph = args->tmph; kh_clear(strdict, tmph); maux_t *ma = args->maux; ma->nAGR_info = 0; out->n_info = 0; info_rules_reset(args); for (i=0; inreaders; i++) { bcf1_t *line = maux_get_line(args,i); if ( !line ) continue; int irec = ma->buf[i].cur; bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; for (j=0; jn_info; j++) { bcf_info_t *inf = &line->d.info[j]; const char *key = hdr->id[BCF_DT_ID][inf->key].key; // AC and AN are done in merge_format() after genotypes are done if (!args->keep_AC_AN && (key[0] == 'A' && (key[1] == 'C' || key[1] == 'N') && key[2] == 0)) continue; int id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, key); if ( id==-1 ) error("Error: The INFO field is not defined in the header: %s\n", key); kitr = kh_get(strdict, tmph, key); // have we seen the tag in one of the readers? int len = bcf_hdr_id2length(hdr,BCF_HL_INFO,inf->key); if ( args->nrules ) { info_rule_t *rule = (info_rule_t*) bsearch(key, args->rules, args->nrules, sizeof(*args->rules), info_rules_comp_key); if ( rule ) { maux1_t *als = ( len==BCF_VL_A || len==BCF_VL_G || len==BCF_VL_R ) ? &ma->buf[i].rec[irec] : NULL; if ( info_rules_add_values(args, hdr, line, rule, als, len) ) continue; } } // Todo: Number=AGR tags should use the newer info_rules_* functions (info_rules_merge_first to be added) // and merge_AGR_info_tag to be made obsolete. if ( len==BCF_VL_A || len==BCF_VL_G || len==BCF_VL_R ) // Number=R,G,A requires special treatment { if ( kitr == kh_end(tmph) ) { // seeing this key for the first time ma->nAGR_info++; hts_expand0(AGR_info_t,ma->nAGR_info,ma->mAGR_info,ma->AGR_info); kitr = kh_put(strdict, tmph, key, &ret); kh_val(tmph,kitr) = ma->nAGR_info - 1; ma->AGR_info[ma->nAGR_info-1].hdr_tag = key; ma->AGR_info[ma->nAGR_info-1].type = bcf_hdr_id2type(hdr,BCF_HL_INFO,inf->key); ma->AGR_info[ma->nAGR_info-1].nbuf = 0; // size of the buffer switch (len) { case BCF_VL_A: ma->AGR_info[ma->nAGR_info-1].nvals = ma->nout_als - 1; break; case BCF_VL_G: ma->AGR_info[ma->nAGR_info-1].nvals = bcf_alleles2gt(ma->nout_als-1,ma->nout_als-1)+1; break; case BCF_VL_R: ma->AGR_info[ma->nAGR_info-1].nvals = ma->nout_als; break; } } kitr = kh_get(strdict, tmph, key); int idx = kh_val(tmph, kitr); if ( idx<0 ) error("Error occurred while processing INFO tag \"%s\" at %s:%"PRId64"\n", key,bcf_seqname(hdr,line),(int64_t) line->pos+1); merge_AGR_info_tag(hdr, line,inf,len,&ma->buf[i].rec[irec],&ma->AGR_info[idx]); continue; } if ( kitr == kh_end(tmph) ) { // Seeing this key for the first time. Although quite hacky, // this is faster than anything else given the data structures.. hts_expand0(bcf_info_t,out->n_info+1,out->d.m_info,out->d.info); out->d.info[out->n_info].key = id; out->d.info[out->n_info].type = inf->type; out->d.info[out->n_info].len = inf->len; out->d.info[out->n_info].v1.i = inf->v1.i; out->d.info[out->n_info].v1.f = inf->v1.f; out->d.info[out->n_info].vptr_off = inf->vptr_off; out->d.info[out->n_info].vptr_len = inf->vptr_len; out->d.info[out->n_info].vptr_free = 1; out->d.info[out->n_info].vptr = (uint8_t*) malloc(inf->vptr_len+inf->vptr_off); memcpy(out->d.info[out->n_info].vptr,inf->vptr-inf->vptr_off, inf->vptr_len+inf->vptr_off); out->d.info[out->n_info].vptr += inf->vptr_off; if ( (args->output_type & FT_BCF) && id!=bcf_hdr_id2int(hdr, BCF_DT_ID, key) ) bcf_info_set_id(out, &out->d.info[out->n_info], id, &args->tmps); out->d.shared_dirty |= BCF1_DIRTY_INF; out->n_info++; kitr = kh_put(strdict, tmph, key, &ret); kh_val(tmph,kitr) = -(out->n_info-1); // arbitrary negative value } } } for (i=0; inrules; i++) args->rules[i].merger(args->out_hdr, out, &args->rules[i]); for (i=0; inAGR_info; i++) { AGR_info_t *agr = &ma->AGR_info[i]; bcf_update_info(out_hdr,out,agr->hdr_tag,agr->buf,agr->nvals,agr->type); } } void update_AN_AC(bcf_hdr_t *hdr, bcf1_t *line) { int32_t an = 0, *tmp = (int32_t*) malloc(sizeof(int)*line->n_allele); int ret = bcf_calc_ac(hdr, line, tmp, BCF_UN_FMT); if ( ret>0 ) { int i; for (i=0; in_allele; i++) an += tmp[i]; bcf_update_info_int32(hdr, line, "AN", &an, 1); bcf_update_info_int32(hdr, line, "AC", tmp+1, line->n_allele-1); } free(tmp); } static inline int max_used_gt_ploidy(bcf_fmt_t *fmt, int nsmpl) { int i,j, max_ploidy = 0; #define BRANCH(type_t, convert, vector_end) { \ uint8_t *ptr = fmt->p; \ for (i=0; in; j++) \ if ( convert(&ptr[j * sizeof(type_t)])==vector_end ) break; \ if ( j==fmt->n ) \ { \ /* all fields were used */ \ if ( max_ploidy < j ) max_ploidy = j; \ break; \ } \ if ( max_ploidy < j ) max_ploidy = j; \ ptr += fmt->n * sizeof(type_t); \ } \ } switch (fmt->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, bcf_int32_vector_end); break; default: error("Unexpected case: %d\n", fmt->type); } #undef BRANCH return max_ploidy; } // Sets ma->laa to local indexes relevant for each sample or missing/vector_end. // The indexes are with respect to the source indexes and must be translated as // the very last step. void init_local_alleles(args_t *args, bcf1_t *out, int ifmt_PL) { bcf_srs_t *files = args->files; maux_t *ma = args->maux; int i,j,k,l, ismpl = 0, nlaa = 0; static int warned = 0; hts_expand(double,out->n_allele,ma->ntmpd,ma->tmpd); // allele probabilities hts_expand(int,out->n_allele,ma->ntmpi,ma->tmpi); // indexes of the sorted probabilities // Let map[] be the mapping from src to output idx. Then k2k[] is mapping from src allele idxs to src allele idxs // reordered so that if in_allele,ma->nk2k,ma->k2k); // Determine local alleles: either take all that are present in the reader or use PL to determine the best // subset for each sample. The alleles must be listed in the order of the alleles in the output file. for (i=0; inreaders; i++) { bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; bcf_fmt_t *fmt_ori = ma->fmt_map[files->nreaders*ifmt_PL+i]; bcf1_t *line = maux_get_line(args, i); int nsmpl = bcf_hdr_nsamples(hdr); if ( line ) { if ( nlaa < line->n_allele - 1 ) nlaa = line->n_allele - 1 <= args->local_alleles ? line->n_allele - 1 : args->local_alleles; for (j=0; jn_allele; j++) ma->k2k[j] = j; if ( line->n_allele <= args->local_alleles + 1 ) { // sort to the output order, insertion sort, ascending int *map = ma->buf[i].rec[ma->buf[i].cur].map; int *k2k = ma->k2k; int tmp; for (k=1; kn_allele; k++) for (l=k; l>0 && map[k2k[l]] < map[k2k[l-1]]; l--) tmp = k2k[l], k2k[l] = k2k[l-1], k2k[l-1] = tmp; // fewer than the allowed number of alleles, use all alleles from this file for (j=0; jlaa + (1+args->local_alleles)*ismpl; for (k=0; kn_allele; k++) ptr[k] = k2k[k]; for (; k<=args->local_alleles; k++) ptr[k] = bcf_int32_vector_end; ismpl++; } continue; } } if ( !line || !fmt_ori ) { // no values, fill in missing values for (j=0; jlaa + (1+args->local_alleles)*ismpl; ptr[0] = bcf_int32_missing; for (k=1; k<=args->local_alleles; k++) ptr[k] = bcf_int32_vector_end; ismpl++; } continue; } // there are more alternate alleles in the input files than is allowed on output, need to subset if ( ifmt_PL==-1 ) { if ( !warned ) fprintf(stderr,"Warning: local alleles are determined from FORMAT/PL but the tag is missing, cannot apply --local-alleles\n"); warned = 1; ma->nlaa = 0; return; } if ( !IS_VL_G(hdr, fmt_ori->id) ) error("FORMAT/PL must be defined as Number=G\n"); if ( 2*fmt_ori->n != line->n_allele*(line->n_allele+1) ) error("Todo: haploid PL to LPL\n"); int *map = ma->buf[i].rec[ma->buf[i].cur].map; double *allele_prob = ma->tmpd; int *idx = ma->tmpi; #define BRANCH(src_type_t, convert, src_is_missing, src_is_vector_end, pl2prob_idx) { \ uint8_t *src = fmt_ori->p; \ for (j=0; jn_allele; k++) allele_prob[k] = 0; \ for (k=0; kn_allele; k++) \ for (l=0; l<=k; l++) \ { \ src_type_t val = convert(src); \ if ( !(src_is_missing) && !(src_is_vector_end) ) \ { \ double prob = ma->pl2prob[pl2prob_idx]; \ allele_prob[k] += prob; \ allele_prob[l] += prob; \ } \ src += sizeof(src_type_t); \ } \ /* insertion sort by allele probability, descending order, with the twist that REF (idx=0) always comes first */ \ allele_prob++; idx[0] = -1; idx++; /* keep REF first */ \ int si,sj,tmp; \ for (si=0; sin_allele-1; si++) idx[si] = si; \ for (si=1; sin_allele-1; si++) \ for (sj=si; sj>0 && allele_prob[idx[sj]] > allele_prob[idx[sj-1]]; sj--) \ tmp = idx[sj], idx[sj] = idx[sj-1], idx[sj-1] = tmp; \ /*for debugging only: test order*/ \ for (si=1; sin_allele-1; si++) \ assert( allele_prob[idx[si-1]] >= allele_prob[idx[si]] ); \ allele_prob--; idx--; /* this was to keep REF first */ \ int32_t *ptr = ma->laa + (1+args->local_alleles)*ismpl; \ ptr[0] = 0; \ for (k=1; k<=args->local_alleles && kn_allele; k++) ptr[k] = idx[k]+1; \ int kmax = k; \ for (; k<=args->local_alleles; k++) ptr[k] = bcf_int32_vector_end; \ /* insertion sort by indexes to the output order, ascending */ \ for (k=1; k0 && map[ptr[l]] < map[ptr[l-1]]; l--) \ tmp = ptr[l], ptr[l] = ptr[l-1], ptr[l-1] = tmp; \ ismpl++; \ } \ } switch (fmt_ori->type) { case BCF_BT_INT8: BRANCH( int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, val); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, val>=0 && val=0 && valtype); } #undef BRANCH } ma->nlaa = nlaa; } void update_local_alleles(args_t *args, bcf1_t *out) { bcf_srs_t *files = args->files; maux_t *ma = args->maux; int i,j,k,ismpl=0,nsamples = bcf_hdr_nsamples(args->out_hdr); for (i=0; inreaders; i++) { int irec = ma->buf[i].cur; bcf_sr_t *reader = &files->readers[i]; int nsmpl = bcf_hdr_nsamples(reader->header); for (k=0; klaa + ismpl*(1+args->local_alleles); int32_t *dst = ma->laa + ismpl*ma->nlaa; j = 0; if ( irec>=0 ) { for (; jnlaa; j++) { if ( src[j+1]==bcf_int32_missing ) dst[j] = bcf_int32_missing; else if ( src[j+1]==bcf_int32_vector_end ) break; else dst[j] = ma->buf[i].rec[irec].map[src[j+1]]; } } if ( j==0 ) dst[j++] = bcf_int32_missing; for (; jnlaa; j++) src[j] = bcf_int32_vector_end; ismpl++; } } bcf_update_format_int32(args->out_hdr, out, "LAA", ma->laa, nsamples*ma->nlaa); } void merge_GT(args_t *args, bcf_fmt_t **fmt_map, bcf1_t *out) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; maux_t *ma = args->maux; int i, ismpl = 0, nsamples = bcf_hdr_nsamples(out_hdr); static int warned = 0; int nsize = 0; for (i=0; inreaders; i++) { bcf_fmt_t *fmt = fmt_map[i]; if ( !fmt ) continue; int pld = max_used_gt_ploidy(fmt_map[i], bcf_hdr_nsamples(bcf_sr_get_header(args->files,i))); if ( nsize < pld ) nsize = pld; } if ( nsize==0 ) nsize = 1; size_t msize = sizeof(int32_t)*nsize*nsamples; if ( msize > 2147483647 ) { if ( !warned ) fprintf(stderr,"Warning: Too many genotypes at %s:%"PRId64", requires %zu bytes, skipping.\n", bcf_seqname(out_hdr,out),(int64_t) out->pos+1,msize); warned = 1; return; } if ( ma->ntmp_arr < msize ) { ma->tmp_arr = realloc(ma->tmp_arr, msize); if ( !ma->tmp_arr ) error("Could not allocate %zu bytes\n",msize); ma->ntmp_arr = msize; } memset(ma->smpl_ploidy,0,nsamples*sizeof(int)); int default_gt = args->missing_to_ref ? bcf_gt_unphased(0) : bcf_gt_missing; for (i=0; inreaders; i++) { bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; bcf_fmt_t *fmt_ori = fmt_map[i]; int32_t *tmp = (int32_t *) ma->tmp_arr + ismpl*nsize; int irec = ma->buf[i].cur; int j,k; if ( !fmt_ori ) { // missing values: assume maximum ploidy for (j=0; jsmpl_ploidy[ismpl+j]++; } tmp += nsize; } ismpl += bcf_hdr_nsamples(hdr); continue; } #define BRANCH(type_t, convert, vector_end) { \ uint8_t *p_ori = fmt_ori->p; \ if ( !ma->buf[i].rec[irec].als_differ ) \ { \ /* the allele numbering is unchanged */ \ for (j=0; jn; k++) \ { \ type_t val = convert(&p_ori[k * sizeof(type_t)]); \ if ( val==vector_end ) break; /* smaller ploidy */ \ ma->smpl_ploidy[ismpl+j]++; \ if ( bcf_gt_is_missing(val) ) tmp[k] = 0; /* missing allele */ \ else tmp[k] = val; \ } \ for (; kn * sizeof(type_t); \ } \ ismpl += bcf_hdr_nsamples(hdr); \ continue; \ } \ /* allele numbering needs to be changed */ \ for (j=0; jn; k++) \ { \ type_t val = convert(&p_ori[k * sizeof(type_t)]); \ if ( val==vector_end ) break; /* smaller ploidy */ \ ma->smpl_ploidy[ismpl+j]++; \ if ( bcf_gt_is_missing(val) ) tmp[k] = 0; /* missing allele */ \ else \ { \ int al = (val>>1) - 1; \ al = al<=0 ? al + 1 : ma->buf[i].rec[irec].map[al] + 1; \ tmp[k] = (al << 1) | ((val)&1); \ } \ } \ for (; kn * sizeof(type_t); \ } \ ismpl += bcf_hdr_nsamples(hdr); \ } switch (fmt_ori->type) { case BCF_BT_INT8: BRANCH(int8_t, le_to_i8, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH(int16_t, le_to_i16, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, le_to_i32, bcf_int32_vector_end); break; default: error("Unexpected case: %d\n", fmt_ori->type); } #undef BRANCH } bcf_update_format_int32(out_hdr, out, "GT", (int32_t*)ma->tmp_arr, nsamples*nsize); } void merge_format_string(args_t *args, const char *key, bcf_fmt_t **fmt_map, bcf1_t *out, int length, int nsize) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; maux_t *ma = args->maux; int i,j, nsamples = bcf_hdr_nsamples(out_hdr); static int warned = 0; // initialize empty strings, a dot for each value, e.g. ".,.,." int nmax = 0; for (i=0; istr[i]; if ( length==BCF_VL_FIXED || length==BCF_VL_VAR ) { str->l = 1; ks_resize(str, str->l+1); str->s[0] = '.'; } else { str->l = nsize*2 - 1; ks_resize(str, str->l+1); str->s[0] = '.'; for (j=1; js[j*2-1] = ',', str->s[j*2] = '.'; } str->s[str->l] = 0; if ( nmax < str->l ) nmax = str->l; } // fill in values for each sample int ismpl = 0; for (i=0; inreaders; i++) { bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; bcf_fmt_t *fmt_ori = fmt_map[i]; if ( !fmt_ori ) { // the field is not present in this file ismpl += bcf_hdr_nsamples(hdr); continue; } bcf1_t *line = maux_get_line(args, i); int irec = ma->buf[i].cur; char *src = (char*) fmt_ori->p; if ( length==BCF_VL_FIXED || length==BCF_VL_VAR || (line->n_allele==out->n_allele && !ma->buf[i].rec[irec].als_differ) ) { // alleles unchanged, copy over for (j=0; jstr[ismpl++]; str->l = 0; kputsn(src, fmt_ori->n, str); if ( nmax < str->l ) nmax = str->l; src += fmt_ori->n; } continue; } // NB, what is below is not the fastest way, copy_string_field() keeps // finding the indexes repeatedly at multiallelic sites if ( length==BCF_VL_A || length==BCF_VL_R ) { int ifrom = length==BCF_VL_A ? 1 : 0; for (j=0; jstr[ismpl++]; int iori,inew; for (iori=ifrom; iorin_allele; iori++) { inew = ma->buf[i].rec[irec].map[iori] - ifrom; int ret = copy_string_field(src, iori - ifrom, fmt_ori->size, str, inew); if ( ret<-1 ) error("[E::%s] fixme: internal error at %s:%"PRId64" .. %d\n",__func__,bcf_seqname(hdr,line),(int64_t) line->pos+1,ret); } if ( nmax < str->l ) nmax = str->l; src += fmt_ori->size; } continue; } assert( length==BCF_VL_G ); error("[E::%s] Merging of Number=G FORMAT strings (in your case FORMAT/%s) is not supported yet, sorry!\n" "Please open an issue on github if this feature is essential for you. However, note that using FORMAT strings is not\n" "a good idea in general - it is slow to parse and does not compress well, it is better to use integer codes instead.\n" "If you don't really need it, use `bcftools annotate -x` to remove the annotation before merging.\n", __func__,key); } // update the record size_t msize = nsamples*nmax; if ( msize > 2147483647 ) { if ( !warned ) fprintf(stderr,"Warning: The row size is too big for FORMAT/%s at %s:%"PRId64", requires %zu bytes, skipping.\n", key,bcf_seqname(out_hdr,out),(int64_t) out->pos+1,msize); warned = 1; return; } if ( ma->ntmp_arr < msize ) { ma->tmp_arr = realloc(ma->tmp_arr, msize); if ( !ma->tmp_arr ) error("Could not allocate %zu bytes\n",msize); ma->ntmp_arr = msize; } char *tgt = (char*) ma->tmp_arr; for (i=0; istr[i].s, ma->str[i].l); if ( ma->str[i].l < nmax ) memset(tgt + ma->str[i].l, 0, nmax - ma->str[i].l); tgt += nmax; } bcf_update_format_char(out_hdr, out, key, (float*)ma->tmp_arr, nsamples*nmax); } // Note: only diploid Number=G tags only for now void merge_localized_numberG_format_field(args_t *args, bcf_fmt_t **fmt_map, bcf1_t *out, int irdr) { int i,j,k, nsamples = bcf_hdr_nsamples(args->out_hdr); bcf_srs_t *files = args->files; maux_t *ma = args->maux; bcf_fmt_t *fmt = fmt_map[irdr]; const char *key = files->readers[irdr].header->id[BCF_DT_ID][fmt_map[irdr]->id].key; size_t nsize = (ma->nlaa+1)*(ma->nlaa+2)/2; // max number of Number=G localized fields size_t msize = sizeof(float)>sizeof(int32_t) ? sizeof(float) : sizeof(int32_t); msize *= nsamples*nsize; if ( msize > 2147483647 ) { static int warned = 0; if ( !warned ) fprintf(stderr,"Warning: The row size is too big for FORMAT/%s at %s:%"PRId64", requires %zu bytes, skipping.\n", key,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,msize); warned = 1; return; } if ( ma->ntmp_arr < msize ) { ma->tmp_arr = realloc(ma->tmp_arr, msize); if ( !ma->tmp_arr ) error("Failed to allocate %zu bytes at %s:%"PRId64" for FORMAT/%s\n", msize,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,key); ma->ntmp_arr = msize; } int ismpl = 0; for (i=0; inreaders; i++) { bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; bcf_fmt_t *fmt_ori = fmt_map[i]; bcf1_t *line = maux_get_line(args, i); int nsmpl = bcf_hdr_nsamples(hdr); if ( !fmt_ori ) { // fill missing values #define BRANCH(tgt_type_t, tgt_set_missing, tgt_set_vector_end) { \ for (j=0; jtmp_arr + ismpl*nsize; \ tgt_set_missing; \ for (k=1; ktype) { case BCF_BT_INT8: BRANCH(int32_t, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_INT16: BRANCH(int32_t, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_FLOAT: BRANCH(float, bcf_float_set_missing(*tgt), bcf_float_set_vector_end(*tgt)); break; default: error("Unexpected case: %d, %s\n", fmt->type, key); } #undef BRANCH continue; } if ( 2*fmt_ori->n!=line->n_allele*(line->n_allele+1) ) error("Todo: localization of missing or haploid Number=G tags\n"); // localize #define BRANCH(tgt_type_t, src_type_t, convert, src_is_missing, src_is_vector_end, tgt_set_missing, tgt_set_vector_end) { \ for (j=0; jp + sizeof(src_type_t)*j*fmt_ori->n; \ tgt_type_t *tgt = (tgt_type_t *) ma->tmp_arr + ismpl*nsize; \ int *laa = ma->laa + (1+args->local_alleles)*ismpl; \ int ii,ij,tgt_idx = 0; \ for (ii=0; ii<=ma->nlaa; ii++) \ { \ if ( laa[ii]==bcf_int32_missing || laa[ii]==bcf_int32_vector_end ) break; \ for (ij=0; ij<=ii; ij++) \ { \ int src_idx = bcf_alleles2gt(laa[ii],laa[ij]); \ src_type_t val = convert(&src[src_idx * sizeof(src_type_t)]); \ if ( src_is_missing ) tgt_set_missing; \ else if ( src_is_vector_end ) break; \ else tgt[tgt_idx] = val; \ tgt_idx++; \ } \ } \ if ( !tgt_idx ) { tgt_set_missing; tgt_idx++; } \ for (; tgt_idxtype) { case BCF_BT_INT8: BRANCH(int32_t, int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, tgt[tgt_idx]=bcf_int32_missing, tgt[tgt_idx]=bcf_int32_vector_end); break; case BCF_BT_INT16: BRANCH(int32_t, int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, tgt[tgt_idx]=bcf_int32_missing, tgt[tgt_idx]=bcf_int32_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, int32_t, le_to_i16, val==bcf_int32_missing, val==bcf_int32_vector_end, tgt[tgt_idx]=bcf_int32_missing, tgt[tgt_idx]=bcf_int32_vector_end); break; case BCF_BT_FLOAT: BRANCH(float, float, le_to_float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), bcf_float_set_missing(tgt[tgt_idx]), bcf_float_set_vector_end(tgt[tgt_idx])); break; default: error("Unexpected case: %d, %s\n", fmt_ori->type, key); } #undef BRANCH } args->tmps.l = 0; kputc('L',&args->tmps); kputs(key,&args->tmps); if ( fmt_map[irdr]->type==BCF_BT_FLOAT ) bcf_update_format_float(args->out_hdr, out, args->tmps.s, (float*)ma->tmp_arr, nsamples*nsize); else bcf_update_format_int32(args->out_hdr, out, args->tmps.s, (int32_t*)ma->tmp_arr, nsamples*nsize); ma->laa_dirty = 1; } void merge_localized_numberAR_format_field(args_t *args, bcf_fmt_t **fmt_map, bcf1_t *out, int irdr) { int i,j,k, nsamples = bcf_hdr_nsamples(args->out_hdr); bcf_srs_t *files = args->files; maux_t *ma = args->maux; bcf_fmt_t *fmt = fmt_map[irdr]; const char *key = files->readers[irdr].header->id[BCF_DT_ID][fmt->id].key; size_t nsize = IS_VL_R(files->readers[irdr].header, fmt->id) ? ma->nlaa + 1 : ma->nlaa; size_t msize = sizeof(float)>sizeof(int32_t) ? sizeof(float) : sizeof(int32_t); msize *= nsamples*nsize; if ( msize > 2147483647 ) { static int warned = 0; if ( !warned ) fprintf(stderr,"Warning: The row size is too big for FORMAT/%s at %s:%"PRId64", requires %zu bytes, skipping.\n", key,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,msize); warned = 1; return; } if ( ma->ntmp_arr < msize ) { ma->tmp_arr = realloc(ma->tmp_arr, msize); if ( !ma->tmp_arr ) error("Failed to allocate %zu bytes at %s:%"PRId64" for FORMAT/%s\n", msize,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,key); ma->ntmp_arr = msize; } int ismpl = 0, ibeg = IS_VL_R(files->readers[irdr].header, fmt->id) ? 0 : 1;; for (i=0; inreaders; i++) { bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; bcf_fmt_t *fmt_ori = fmt_map[i]; int nsmpl = bcf_hdr_nsamples(hdr); if ( !fmt_ori ) { // fill missing values #define BRANCH(tgt_type_t, tgt_set_missing, tgt_set_vector_end) { \ for (j=0; jtmp_arr + ismpl*nsize; \ tgt_set_missing; \ for (k=1; ktype) { case BCF_BT_INT8: BRANCH(int32_t, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_INT16: BRANCH(int32_t, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_FLOAT: BRANCH(float, bcf_float_set_missing(*tgt), bcf_float_set_vector_end(*tgt)); break; default: error("Unexpected case: %d, %s\n", fmt->type, key); } #undef BRANCH continue; } // localize #define BRANCH(tgt_type_t, src_type_t, convert, src_is_missing, src_is_vector_end, tgt_set_missing, tgt_set_vector_end) { \ for (j=0; jp + sizeof(src_type_t)*j*fmt_ori->n; \ tgt_type_t *tgt = (tgt_type_t *) ma->tmp_arr + ismpl*nsize; \ int *laa = ma->laa + (1+args->local_alleles)*ismpl; \ int ii,tgt_idx = 0; \ for (ii=ibeg; ii<=ma->nlaa; ii++) \ { \ if ( laa[ii]==bcf_int32_missing || laa[ii]==bcf_int32_vector_end ) break; \ int src_idx = laa[ii] - ibeg; \ src_type_t val = convert(&src[src_idx * sizeof(src_type_t)]); \ if ( src_is_missing ) tgt_set_missing; \ else if ( src_is_vector_end ) break; \ else tgt[tgt_idx] = val; \ tgt_idx++; \ } \ if ( !tgt_idx ) { tgt_set_missing; tgt_idx++; } \ for (; tgt_idxtype) { case BCF_BT_INT8: BRANCH(int32_t, int8_t, le_to_i8, val==bcf_int8_missing, val==bcf_int8_vector_end, tgt[tgt_idx]=bcf_int32_missing, tgt[tgt_idx]=bcf_int32_vector_end); break; case BCF_BT_INT16: BRANCH(int32_t, int16_t, le_to_i16, val==bcf_int16_missing, val==bcf_int16_vector_end, tgt[tgt_idx]=bcf_int32_missing, tgt[tgt_idx]=bcf_int32_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, int32_t, le_to_i32, val==bcf_int32_missing, val==bcf_int32_vector_end, tgt[tgt_idx]=bcf_int32_missing, tgt[tgt_idx]=bcf_int32_vector_end); break; case BCF_BT_FLOAT: BRANCH(float, float, le_to_float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), bcf_float_set_missing(tgt[tgt_idx]), bcf_float_set_vector_end(tgt[tgt_idx])); break; default: error("Unexpected case: %d, %s\n", fmt_ori->type, key); } #undef BRANCH } args->tmps.l = 0; kputc('L',&args->tmps); kputs(key,&args->tmps); if ( fmt_map[irdr]->type==BCF_BT_FLOAT ) bcf_update_format_float(args->out_hdr, out, args->tmps.s, (float*)ma->tmp_arr, nsamples*nsize); else bcf_update_format_int32(args->out_hdr, out, args->tmps.s, (int32_t*)ma->tmp_arr, nsamples*nsize); ma->laa_dirty = 1; } void merge_format_field(args_t *args, bcf_fmt_t **fmt_map, missing_rule_t *mrule, bcf1_t *out) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; maux_t *ma = args->maux; int i, ismpl = 0, nsamples = bcf_hdr_nsamples(out_hdr); static int warned = 0; const char *key = NULL; size_t nsize = 0, length = BCF_VL_FIXED; int type = -1; for (i=0; inreaders; i++) { if ( !maux_get_line(args,i) ) continue; if ( !fmt_map[i] ) continue; if ( !key ) key = files->readers[i].header->id[BCF_DT_ID][fmt_map[i]->id].key; type = fmt_map[i]->type; if ( IS_VL_G(files->readers[i].header, fmt_map[i]->id) ) { length = BCF_VL_G; nsize = out->n_allele*(out->n_allele + 1)/2; break; } if ( IS_VL_A(files->readers[i].header, fmt_map[i]->id) ) { length = BCF_VL_A; nsize = out->n_allele - 1; break; } if ( IS_VL_R(files->readers[i].header, fmt_map[i]->id) ) { length = BCF_VL_R; nsize = out->n_allele; break; } if ( fmt_map[i]->n > nsize ) nsize = fmt_map[i]->n; } if ( ma->nlaa && length!=BCF_VL_FIXED ) { if ( length==BCF_VL_G ) merge_localized_numberG_format_field(args,fmt_map,out,i); else if ( length==BCF_VL_A || length==BCF_VL_R ) merge_localized_numberAR_format_field(args,fmt_map,out,i); return; } if ( type==BCF_BT_CHAR ) { merge_format_string(args, key, fmt_map, out, length, nsize); return; } size_t msize = sizeof(float)>sizeof(int32_t) ? sizeof(float) : sizeof(int32_t); msize *= nsamples*nsize; if ( msize > 2147483647 ) { if ( !warned ) fprintf(stderr,"Warning: The row size is too big for FORMAT/%s at %s:%"PRId64", requires %zu bytes, skipping.\n", key,bcf_seqname(out_hdr,out),(int64_t) out->pos+1,msize); warned = 1; return; } if ( ma->ntmp_arr < msize ) { ma->tmp_arr = realloc(ma->tmp_arr, msize); if ( !ma->tmp_arr ) error("Failed to allocate %zu bytes at %s:%"PRId64" for FORMAT/%s\n", msize,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,key); ma->ntmp_arr = msize; } // Fill the temp array for all samples by collecting values from all files for (i=0; inreaders; i++) { bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; bcf_fmt_t *fmt_ori = fmt_map[i]; bcf1_t *line = maux_get_line(args, i); int irec = ma->buf[i].cur; if ( fmt_ori ) { type = fmt_ori->type; int nals_ori = line->n_allele; if ( length==BCF_VL_G ) { // if all fields are missing then n==1 is valid if ( fmt_ori->n!=1 && fmt_ori->n != nals_ori*(nals_ori+1)/2 && fmt_map[i]->n != nals_ori ) error("Incorrect number of FORMAT/%s values at %s:%"PRId64", cannot merge. The tag is defined as Number=G, but found\n" "%d values and %d alleles. See also http://samtools.github.io/bcftools/howtos/FAQ.html#incorrect-nfields\n", key,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,fmt_ori->n,nals_ori); } else if ( length==BCF_VL_A ) { if ( fmt_ori->n!=1 && fmt_ori->n != nals_ori-1 ) error("Incorrect number of FORMAT/%s values at %s:%"PRId64", cannot merge. The tag is defined as Number=A, but found\n" "%d values and %d alleles. See also http://samtools.github.io/bcftools/howtos/FAQ.html#incorrect-nfields\n", key,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,fmt_ori->n,nals_ori); } else if ( length==BCF_VL_R ) { if ( fmt_ori->n!=1 && fmt_ori->n != nals_ori ) error("Incorrect number of FORMAT/%s values at %s:%"PRId64", cannot merge. The tag is defined as Number=R, but found\n" "%d values and %d alleles. See also http://samtools.github.io/bcftools/howtos/FAQ.html#incorrect-nfields\n", key,bcf_seqname(args->out_hdr,out),(int64_t) out->pos+1,fmt_ori->n,nals_ori); } } // set the values #define BRANCH(tgt_type_t, src_type_t, convert, src_is_missing, src_is_vector_end, tgt_set_missing, tgt_set_vector_end) { \ int j, l, k; \ tgt_type_t *tgt = (tgt_type_t *) ma->tmp_arr + ismpl*nsize; \ if ( !fmt_ori ) \ { \ /* the field is not present in this file, set missing values */ \ for (j=0; jp; \ if ( (length!=BCF_VL_G && length!=BCF_VL_A && length!=BCF_VL_R) || (line->n_allele==out->n_allele && !ma->buf[i].rec[irec].als_differ) ) \ { \ /* alleles unchanged, copy over */ \ for (j=0; jn; l++) \ { \ if ( src_is_vector_end ) break; \ else if ( src_is_missing ) tgt_set_missing; \ else *tgt = convert(src); \ tgt++; src += sizeof(src_type_t); \ } \ for (k=l; kn - l); \ } \ ismpl += bcf_hdr_nsamples(hdr); \ continue; \ } \ /* allele numbering needs to be changed */ \ if ( length==BCF_VL_G ) \ { \ /* Number=G tags */ \ for (j=0; jtmp_arr + (ismpl+j)*nsize; \ src = fmt_ori->p + sizeof(src_type_t) * j * fmt_ori->n; \ int tag_missing = src_is_missing && fmt_ori->n==1; \ if ( src_is_missing && fmt_ori->n>1 ) { \ src += sizeof(src_type_t); \ tag_missing = src_is_vector_end ; \ } \ if ( tag_missing ) \ { \ /* tag with missing value "." */ \ tgt_set_missing; \ for (l=1; lsmpl_ploidy[ismpl+j]==1 ? 1 : 0; \ int ngsize = haploid ? out->n_allele : out->n_allele*(out->n_allele + 1)/2; \ if ( ma->buf[i].unkn_allele ) /* Use value from the unknown allele when available */ \ { \ src = fmt_ori->p + sizeof(src_type_t)*j*fmt_ori->n; \ int iunkn = haploid ? ma->buf[i].unkn_allele : (ma->buf[i].unkn_allele+1)*(ma->buf[i].unkn_allele + 2)/2 - 1; \ src_type_t val = convert(&src[iunkn * sizeof(src_type_t)]); \ for (l=0; ltype==MERGE_MISSING_CONST ) \ { \ for (l=0; lvalue; tgt++; } \ } \ else if ( mrule && mrule->type==MERGE_MISSING_MAX ) \ { \ src = fmt_ori->p + sizeof(src_type_t)*j*fmt_ori->n; \ src_type_t max = convert(src); \ for (l=1; ln; l++) \ { \ src_type_t val = convert(&src[l * sizeof(src_type_t)]); \ if ( max < val ) max = val; \ } \ for (l=0; ln_allele; iori++) \ { \ inew = ma->buf[i].rec[irec].map[iori]; \ src = fmt_ori->p + (j*fmt_ori->n + iori) * sizeof(src_type_t); \ tgt = (tgt_type_t *) ma->tmp_arr + (ismpl+j)*nsize + inew; \ if ( src_is_vector_end ) break; \ if ( src_is_missing ) tgt_set_missing; \ else *tgt = convert(src); \ } \ } \ else \ { \ /* Diploid */ \ int iori,jori, inew,jnew; \ for (iori=0; iorin_allele; iori++) \ { \ inew = ma->buf[i].rec[irec].map[iori]; \ for (jori=0; jori<=iori; jori++) \ { \ jnew = ma->buf[i].rec[irec].map[jori]; \ int kori = iori*(iori+1)/2 + jori; \ int knew = inew>jnew ? inew*(inew+1)/2 + jnew : jnew*(jnew+1)/2 + inew; \ src = fmt_ori->p + (j*fmt_ori->n + kori) * sizeof(src_type_t); \ tgt = (tgt_type_t *) ma->tmp_arr + (ismpl+j)*nsize + knew; \ if ( src_is_vector_end ) \ { \ iori = line->n_allele; \ break; \ } \ if ( src_is_missing ) tgt_set_missing; \ else *tgt = convert(src); \ } \ } \ } \ } \ } \ else \ { \ /* Number=A or Number=R tags */ \ int ifrom = length==BCF_VL_A ? 1 : 0; \ for (j=0; jtmp_arr + (ismpl+j)*nsize; \ src = fmt_ori->p + j*fmt_ori->size; \ int tag_missing = src_is_missing && fmt_ori->n==1; \ if ( src_is_missing && fmt_ori->n>1 ) { \ src += sizeof(src_type_t); \ tag_missing = src_is_vector_end ; \ } \ if ( tag_missing ) \ { \ /* tag with missing value "." */ \ tgt_set_missing; \ for (l=1; lp + j*fmt_ori->size; \ if ( ma->buf[i].unkn_allele ) /* Use value from the unknown allele when available */ \ { \ int iunkn = ma->buf[i].unkn_allele; \ src_type_t val = convert(&src[iunkn * sizeof(src_type_t)]); \ for (l=0; ltype==MERGE_MISSING_CONST ) \ { \ for (l=0; lvalue; tgt++; } \ } \ else if ( mrule && mrule->type==MERGE_MISSING_MAX ) \ { \ src = fmt_ori->p + sizeof(src_type_t)*j*fmt_ori->n; \ src_type_t max = convert(src); \ for (l=1; ln; l++) \ { \ src_type_t val = convert(&src[l * sizeof(src_type_t)]); \ if ( max < val ) max = val; \ } \ for (l=0; ln_allele; iori++) \ { \ inew = ma->buf[i].rec[irec].map[iori] - ifrom; \ tgt = (tgt_type_t *) ma->tmp_arr + (ismpl+j)*nsize + inew; \ if ( src_is_vector_end ) break; \ if ( src_is_missing ) tgt_set_missing; \ else *tgt = convert(src); \ src += sizeof(src_type_t); \ } \ } \ } \ ismpl += bcf_hdr_nsamples(hdr); \ } switch (type) { case BCF_BT_INT8: BRANCH(int32_t, int8_t, le_to_i8, le_to_i8(src)==bcf_int8_missing, le_to_i8(src)==bcf_int8_vector_end, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_INT16: BRANCH(int32_t, int16_t, le_to_i16, le_to_i16(src)==bcf_int16_missing, le_to_i16(src)==bcf_int16_vector_end, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_INT32: BRANCH(int32_t, int32_t, le_to_i32, le_to_i32(src)==bcf_int32_missing, le_to_i32(src)==bcf_int32_vector_end, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; case BCF_BT_FLOAT: BRANCH(float, float, le_to_float, bcf_float_is_missing(le_to_float(src)), bcf_float_is_vector_end(le_to_float(src)), bcf_float_set_missing(*tgt), bcf_float_set_vector_end(*tgt)); break; default: error("Unexpected case: %d, %s\n", type, key); } #undef BRANCH } if ( type==BCF_BT_FLOAT ) bcf_update_format_float(out_hdr, out, key, (float*)ma->tmp_arr, nsamples*nsize); else bcf_update_format_int32(out_hdr, out, key, (int32_t*)ma->tmp_arr, nsamples*nsize); } void merge_format(args_t *args, bcf1_t *out) { bcf_srs_t *files = args->files; bcf_hdr_t *out_hdr = args->out_hdr; maux_t *ma = args->maux; if ( !ma->nfmt_map ) { ma->nfmt_map = 2; ma->fmt_map = (bcf_fmt_t**) calloc(ma->nfmt_map*files->nreaders, sizeof(bcf_fmt_t*)); ma->fmt_key = (const char**) malloc(ma->nfmt_map*sizeof(*ma->fmt_key)); } else memset(ma->fmt_map, 0, ma->nfmt_map*files->nreaders*sizeof(bcf_fmt_t**)); khiter_t kitr; strdict_t *tmph = args->tmph; kh_clear(strdict, tmph); int i, j, ret, has_GT = 0, has_PL = -1, max_ifmt = 0; // max fmt index for (i=0; inreaders; i++) { bcf1_t *line = maux_get_line(args,i); if ( !line ) continue; bcf_sr_t *reader = &files->readers[i]; bcf_hdr_t *hdr = reader->header; for (j=0; jn_fmt; j++) { // Was this tag already seen? bcf_fmt_t *fmt = &line->d.fmt[j]; const char *key = hdr->id[BCF_DT_ID][fmt->id].key; kitr = kh_get(strdict, tmph, key); int ifmt; if ( kitr != kh_end(tmph) ) ifmt = kh_value(tmph, kitr); // seen else { // new FORMAT tag if ( key[0]=='G' && key[1]=='T' && key[2]==0 ) { has_GT = 1; ifmt = 0; } else { ifmt = ++max_ifmt; if ( max_ifmt >= ma->nfmt_map ) { ma->fmt_map = (bcf_fmt_t**) realloc(ma->fmt_map, sizeof(bcf_fmt_t*)*(max_ifmt+1)*files->nreaders); memset(ma->fmt_map+ma->nfmt_map*files->nreaders, 0, (max_ifmt-ma->nfmt_map+1)*files->nreaders*sizeof(bcf_fmt_t*)); ma->fmt_key = (const char**) realloc(ma->fmt_key, sizeof(*ma->fmt_key)*(max_ifmt+1)); ma->nfmt_map = max_ifmt+1; } if ( key[0]=='P' && key[1]=='L' && key[2]==0 ) { has_PL = ifmt; } ma->fmt_key[max_ifmt] = key; } kitr = kh_put(strdict, tmph, key, &ret); kh_value(tmph, kitr) = ifmt; } ma->fmt_map[ifmt*files->nreaders+i] = fmt; } // Check if the allele numbering must be changed int irec = ma->buf[i].cur; for (j=1; jn_allele; j++) if ( ma->buf[i].rec[irec].map[j]!=j ) break; ma->buf[i].rec[irec].als_differ = j==line->n_allele ? 0 : 1; } if ( args->local_alleles ) { ma->laa_dirty = ma->nlaa = 0; if ( out->n_allele > args->local_alleles + 1 ) init_local_alleles(args, out, has_PL); } out->n_sample = bcf_hdr_nsamples(out_hdr); if ( has_GT ) merge_GT(args, ma->fmt_map, out); if ( !args->keep_AC_AN ) update_AN_AC(out_hdr, out); for (i=1; i<=max_ifmt; i++) { missing_rule_t *rule = (missing_rule_t*) bsearch(ma->fmt_key[i], args->missing_rules, args->nmissing_rules, sizeof(*args->missing_rules), missing_rules_comp_key); merge_format_field(args, &ma->fmt_map[i*files->nreaders], rule, out); } if ( ma->laa_dirty ) update_local_alleles(args, out); out->d.indiv_dirty = 1; } void gvcf_set_alleles(args_t *args) { int i,k; bcf_srs_t *files = args->files; maux_t *maux = args->maux; gvcf_aux_t *gaux = maux->gvcf; for (i=0; inals; i++) { free(maux->als[i]); maux->als[i] = NULL; } maux->nals = 0; for (i=0; inreaders; i++) { if ( !gaux[i].active ) continue; bcf1_t *line = maux_get_line(args, i); if ( !line ) continue; int irec = maux->buf[i].cur; hts_expand(int, line->n_allele, maux->buf[i].rec[irec].mmap, maux->buf[i].rec[irec].map); if ( !maux->nals ) // first record, copy the alleles to the output { maux->nals = line->n_allele; hts_expand0(char*, maux->nals, maux->mals, maux->als); hts_expand0(int, maux->nals, maux->ncnt, maux->cnt); for (k=0; knals; k++) { if ( maux->als[k] ) free(maux->als[k]); maux->als[k] = strdup(line->d.allele[k]); maux->buf[i].rec[irec].map[k] = k; } } else { maux->als = merge_alleles(line->d.allele, line->n_allele, maux->buf[i].rec[irec].map, maux->als, &maux->nals, &maux->mals); if ( !maux->als ) { bcf_hdr_t *hdr = bcf_sr_get_header(args->files,i); error("Failed to merge alleles at %s:%"PRId64"\n",bcf_seqname(hdr,line),(int64_t) line->pos+1); } } } } /* Output staged gVCF blocks, end is the last position of the block. Assuming gaux[i].active flags are set and maux_get_line returns correct lines. Both start,end coordinates are 0-based. */ void gvcf_write_block(args_t *args, int start, int end) { int i; maux_t *maux = args->maux; gvcf_aux_t *gaux = maux->gvcf; assert(gaux); // Update POS int min = INT_MAX; // the minimum active gVCF INFO/END (0-based) char ref = 'N'; for (i=0; ifiles->nreaders; i++) { if ( !gaux[i].active ) continue; if ( ref=='N' && gaux[i].line->pos==start ) ref = gaux[i].line->d.allele[0][0]; gaux[i].line->pos = start; } for (i=0; ifiles->nreaders; i++) { if ( !gaux[i].active ) continue; if ( gaux[i].end < start ) { gaux[i].active = 0; maux->buf[i].cur = -1; continue; } gaux[i].line->d.allele[0][0] = ref; if ( min > gaux[i].end ) min = gaux[i].end; } // Check for valid gVCF blocks in this region if ( min==INT_MAX ) // this probably should not happen { assert(0); maux->gvcf_min = 0; return; } bcf1_t *out = args->out_line; gvcf_set_alleles(args); // Merge the staged lines merge_chrom2qual(args, out); merge_filter(args, out); merge_info(args, out); merge_format(args, out); if ( args->gvcf_fai && out->d.allele[0][0]=='N' ) { int slen = 0; char *seq = faidx_fetch_seq(args->gvcf_fai,maux->chr,out->pos,out->pos,&slen); if (!seq) exit(1); // faidx_fetch_seq has already reported the error. if (slen) { out->d.allele[0][0] = seq[0]; free(seq); } } // Update END boundary if ( end > start ) { end++; bcf_update_info_int32(args->out_hdr, out, "END", &end, 1); } else bcf_update_info_int32(args->out_hdr, out, "END", NULL, 0); int iunseen; if ( args->trim_star_allele && (out->n_allele > 2 || args->trim_star_allele > 1) && (iunseen=get_unseen_allele(out)) && iunseen>0 ) { // the unobserved star allele should be trimmed, either it is variant site or trimming of all sites was requested kbitset_t *rm_set = kbs_init(out->n_allele); kbs_insert(rm_set, iunseen); if ( bcf_remove_allele_set(args->out_hdr,out,rm_set) ) error("[%s] Error: failed to trim the unobserved allele at %s:%"PRIhts_pos"\n",__func__,bcf_seqname(args->out_hdr,out),out->pos+1); kbs_destroy(rm_set); } if ( bcf_write1(args->out_fh, args->out_hdr, out)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); bcf_clear1(out); // Inactivate blocks which do not extend beyond END and find new gvcf_min min = INT_MAX; for (i=0; ifiles->nreaders; i++) { if ( !gaux[i].active ) continue; if ( gaux[i].end < end ) { gaux[i].active = 0; maux->buf[i].cur = -1; continue; } // next min END position bigger than the current one if ( maux->gvcf_min < gaux[i].end+1 && min > gaux[i].end+1 ) min = gaux[i].end + 1; } maux->gvcf_min = min==INT_MAX ? 0 : min; } /* Flush staged gVCF blocks. Flush everything if there are no more lines (done=1) or if there is a new chromosome. If still on the same chromosome, all hanging blocks must be ended by creating new records: A 1 END=10 B 3 END=7 C 3 END=5 out 1 END=2 A . . 3 END=5 A B C 6 END=7 A B . 8 END=10 A . . */ void gvcf_flush(args_t *args, int done) { int i; maux_t *maux = args->maux; if ( !maux->chr ) return; // first time here, nothing to flush int flush_until = INT_MAX; if ( !done ) { // Get current position and chromosome for (i=0; in; i++) if ( bcf_sr_has_line(maux->files,i) ) break; bcf1_t *line = bcf_sr_get_line(maux->files,i); bcf_hdr_t *hdr = bcf_sr_get_header(maux->files,i); if ( !strcmp(maux->chr,bcf_seqname(hdr,line)) ) flush_until = line->pos; // still on the same chr } // When called on a region, trim the blocks accordingly int start = maux->gvcf_break>=0 ? maux->gvcf_break + 1 : maux->pos; // the start of a new gvcf block to output if ( args->regs ) { int rstart = -1, rend = -1; if ( regidx_overlap(args->regs,maux->chr,start,flush_until,args->regs_itr) ) { // In case there are multiple regions, we treat them as one rstart = args->regs_itr->beg; while ( regitr_overlap(args->regs_itr) ) rend = args->regs_itr->end; } if ( rstart > start ) start = rstart; if ( rend < flush_until ) flush_until = rend+1; } // output all finished blocks while ( maux->gvcf_min && start < flush_until ) { // does the block end before the new line or is it interrupted? int tmp = maux->gvcf_min < flush_until ? maux->gvcf_min : flush_until; if ( start > tmp-1 ) break; gvcf_write_block(args,start,tmp-1); // gvcf_min is 1-based, passing 0-based coordinates start = tmp; } } static inline int is_gvcf_block(bcf1_t *line) { if ( line->rlen<=1 ) return 0; if ( strlen(line->d.allele[0])==line->rlen ) return 0; if ( line->n_allele==1 ) return 1; int i; for (i=1; in_allele; i++) { if ( !strcmp(line->d.allele[i],"<*>") ) return 1; if ( !strcmp(line->d.allele[i],"") ) return 1; if ( !strcmp(line->d.allele[i],"") ) return 1; } return 0; } /* Check incoming lines for new gVCF blocks, set pointer to the current source buffer (gvcf or readers). In contrast to gvcf_flush, this function can be called only after maux_reset as it relies on updated maux buffers. The coordinate is 0-based */ void gvcf_stage(args_t *args, int pos) { maux_t *maux = args->maux; gvcf_aux_t *gaux = maux->gvcf; bcf_srs_t *files = args->files; int32_t *end = (int32_t*) maux->tmp_arr; int i, nend = maux->ntmp_arr / sizeof(int32_t); maux->gvcf_break = -1; maux->gvcf_min = INT_MAX; for (i=0; inreaders; i++) { if ( gaux[i].active && gaux[i].end < pos ) gaux[i].active = 0; if ( gaux[i].active ) { // gvcf block should not overlap with another record if ( maux->gvcf_min > gaux[i].end+1 ) maux->gvcf_min = gaux[i].end + 1; maux->buf[i].beg = 0; maux->buf[i].end = 1; maux->buf[i].cur = 0; continue; } // Does any of the lines have END set? It is enough to check only the // first line, there should be no duplicate records with END in gVCF if ( maux->buf[i].beg==maux->buf[i].end ) continue; // no new record int irec = maux->buf[i].beg; bcf_hdr_t *hdr = bcf_sr_get_header(files, i); bcf1_t *line = args->files->readers[i].buffer[irec]; int ret = is_gvcf_block(line) ? bcf_get_info_int32(hdr,line,"END",&end,&nend) : 0; if ( ret==1 ) { if ( end[0] == line->pos + 1 ) // POS and INFO/END are identical, treat as if a normal w/o INFO/END { maux->gvcf_break = line->pos; continue; } if ( end[0] <= line->pos ) error("Error: Incorrect END at %s:%"PRId64" .. END=%d\n", bcf_seqname(hdr,line),(int64_t) line->pos+1,end[0]); // END is set, this is a new gVCF block. Cache this line in gaux[i] and swap with // an empty record: the gaux line must be kept until we reach its END. gaux[i].active = 1; gaux[i].end = end[0] - 1; SWAP(bcf1_t*,args->files->readers[i].buffer[irec],gaux[i].line); gaux[i].line->pos = pos; maux->buf[i].lines = &gaux[i].line; maux->buf[i].beg = 0; maux->buf[i].end = 1; maux->buf[i].cur = 0; // Set the rid,pos of the swapped line in the buffer or else the // synced reader will have a problem with the next line // args->files->readers[i].buffer[irec]->rid = maux->buf[i].rid; args->files->readers[i].buffer[irec]->pos = maux->pos; // Update block offsets if ( maux->gvcf_min > gaux[i].end+1 ) maux->gvcf_min = gaux[i].end + 1; } else maux->gvcf_break = line->pos; // must break the gvcf block } maux->ntmp_arr = nend * sizeof(int32_t); maux->tmp_arr = end; if ( maux->gvcf_min==INT_MAX ) maux->gvcf_min = 0; } void debug_buffers(FILE *fp, bcf_srs_t *files); void debug_buffer(FILE *fp, bcf_srs_t *files, int reader); /* Flush all buffered and processed records with the same coordinate. Note that synced reader discards buffer[0], so that needs to stay untouched. */ void clean_buffer(args_t *args) { maux_t *ma = args->maux; int ir; for (ir=0; irn; ir++) { // Invalidate pointer to reader's buffer or else gvcf_flush will attempt // to use the old lines via maux_get_line() if ( ma->gvcf ) { if ( ma->gvcf[ir].active ) { if ( ma->pos > ma->gvcf[ir].end ) ma->gvcf[ir].active = 0; else if ( ma->buf[ir].cur==-1 ) ma->buf[ir].cur = ma->buf[ir].beg; // re-activate interrupted gVCF block } if ( !ma->gvcf[ir].active ) ma->buf[ir].cur = -1; } bcf_sr_t *reader = bcf_sr_get_reader(args->files,ir); if ( !reader->nbuffer ) continue; // nothing to clean bcf1_t **buf = reader->buffer; if ( buf[1]->rid!=ma->buf[ir].rid || buf[1]->pos!=ma->pos ) continue; // nothing to flush int a = 1, b = 2; while ( b<=reader->nbuffer && buf[b]->rid==ma->buf[ir].rid && buf[b]->pos==ma->pos ) b++; // b now points to the first line we want to preserve while ( b<=reader->nbuffer ) { SWAP(bcf1_t*, buf[a], buf[b]); a++; b++; } reader->nbuffer -= b-a; } } void debug_maux(args_t *args) { bcf_srs_t *files = args->files; maux_t *maux = args->maux; int j,k,l; fprintf(stderr,"Alleles to merge at %d, nals=%d\n", maux->pos+1,maux->nals); for (j=0; jnreaders; j++) { bcf_sr_t *reader = &files->readers[j]; buffer_t *buf = &maux->buf[j]; fprintf(stderr," reader %d (k=%d-%d): ", j,buf->beg,buf->end); for (k=buf->beg; kend; k++) { if ( buf->rec[k].skip & SKIP_DONE ) { fprintf(stderr," DONE"); continue; } bcf1_t *line = reader->buffer[k]; // selected for merging by can_merge fprintf(stderr,"\t"); if ( buf->cur==k ) fprintf(stderr,"!"); // selected for merging by stage_line if ( buf->rec[k].skip ) fprintf(stderr,"["); // this record cannot be merged in this round if ( !line->n_allele && maux->gvcf[j].active ) fprintf(stderr,"<*>"); for (l=0; ln_allele; l++) fprintf(stderr,"%s%s", l==0?"":",", line->d.allele[l]); if ( buf->rec[k].skip ) fprintf(stderr,"]"); } fprintf(stderr,"\n"); } fprintf(stderr," counts: "); for (j=0; jnals; j++) fprintf(stderr,"%s %dx %s", j==0?"":",",maux->cnt[j], maux->als[j]); fprintf(stderr,"\n\n"); } void debug_state(args_t *args) { maux_t *maux = args->maux; int i,j; fprintf(stderr,"State after position=%d done:\n",maux->pos+1); for (i=0; ifiles->nreaders; i++) { fprintf(stderr,"\treader %d:\tcur,beg,end=% d,%d,%d", i,maux->buf[i].cur,maux->buf[i].beg,maux->buf[i].end); if ( maux->buf[i].cur >=0 ) { bcf_hdr_t *hdr = bcf_sr_get_header(args->files,i); const char *chr = bcf_hdr_id2name(hdr, maux->buf[i].rid); fprintf(stderr,"\t"); for (j=maux->buf[i].beg; jbuf[i].end; j++) fprintf(stderr," %s:%"PRId64,chr,(int64_t) maux->buf[i].lines[j]->pos+1); } fprintf(stderr,"\n"); } fprintf(stderr,"\tgvcf_min=%d\n", args->maux->gvcf_min); for (i=0; ifiles->nreaders; i++) { fprintf(stderr,"\t\treader %d:\tgvcf_active=%d", i,maux->gvcf[i].active); if ( maux->gvcf[i].active ) fprintf(stderr,"\tpos,end=%"PRId64",%"PRId64, (int64_t) maux->gvcf[i].line->pos+1,(int64_t) maux->gvcf[i].end+1); fprintf(stderr,"\n"); } fprintf(stderr,"\n"); } // Lines can come with any combination of variant types. We use a subset of types defined in vcf.h // but shift by two bits to account for VCF_REF defined as 0 (design flaw in vcf.h, my fault) static const int snp_mask = (VCF_SNP<<1)|(VCF_MNP<<1), indel_mask = (VCF_INDEL<<1), ins_mask = VCF_INS<<1, del_mask = VCF_DEL<<1, ref_mask = 1; // Can these types be merged given the -m settings? Despite the function's name, its focus is on // excluding incompatible records, there will be a finer matching later in stage_line() static inline int types_compatible(args_t *args, int selected_types, buffer_t *buf, int irec) { int k; maux_t *maux = args->maux; bcf1_t *rec = buf->lines[irec]; int rec_types = buf->rec[irec].var_types; assert( selected_types ); // this is trivially true, set in can_merge() if ( args->collapse & COLLAPSE_ANY ) return 1; // can merge anything with anything // REF and gVCF_REF with no other alleles present can be merged with anything if ( (selected_types&ref_mask) && !(selected_types&(~ref_mask)) ) return 1; if ( (rec_types&ref_mask) && !(rec_types&(~ref_mask)) ) return 1; if ( args->collapse!=COLLAPSE_NONE ) { // If we are here, one the following modes must have been set: both,snps,indels,snp-ins-del // Include the new record if // - rec has SNV, we already have SNV, and -m is both,snps,snp-ins-del // - rec has indel, we already have an indel, and -m both,indels,snp-ins-del if ( args->collapse&(COLLAPSE_SNPS|COLLAPSE_SNP_INS_DEL) ) { if ( (rec_types&snp_mask) && (selected_types&snp_mask) ) return 1; } if ( args->collapse&COLLAPSE_INDELS ) { if ( (rec_types&indel_mask) && (selected_types&indel_mask) ) return 1; } if ( args->collapse&COLLAPSE_SNP_INS_DEL ) { if ( (rec_types&ins_mask) && (selected_types&ins_mask) ) return 1; if ( (rec_types&del_mask) && (selected_types&del_mask) ) return 1; } // Whatever is left, allow to match if the alleles match exactly } // The -m none mode or exact matching requested // Simple test first: are the variants of the same type? int x = selected_types >> 1; // remove REF int y = rec_types >> 1; // remove REF while ( x && y ) { x>>=1; y>>=1; } if ( x || y ) return 0; // the types differ if ( vcmp_set_ref(args->vcmp,maux->als[0],rec->d.allele[0]) < 0 ) return 0; // refs are not compatible for (k=1; kn_allele; k++) { if ( bcf_has_variant_type(rec,k,VCF_REF) ) continue; // this must be gVCF_REF (<*> or ) if ( vcmp_find_allele(args->vcmp,maux->als+1,maux->nals-1,rec->d.allele[k])>=0 ) break; } if ( k==rec->n_allele ) return 0; // this record has a new allele rec->d.allele[k] return 1; // all alleles in rec are also in the records selected thus far, perhaps save for gVCF_REF } static void maux_update_alleles(args_t *args, int ireader, int irec) { int k; bcf_sr_t *reader = &args->files->readers[ireader]; maux_t *maux = args->maux; buffer_t *buf = &maux->buf[ireader]; maux1_t *ma1 = &buf->rec[irec]; bcf1_t *line = buf->lines[irec]; hts_expand(int, line->n_allele, ma1->mmap, ma1->map); if ( !maux->nals ) // first record to be merged, copy the alleles to the output { maux->nals = line->n_allele; hts_expand0(char*, maux->nals, maux->mals, maux->als); hts_expand0(int, maux->nals, maux->ncnt, maux->cnt); hts_expand0(int, maux->nals, maux->mals_types, maux->als_types); for (k=0; knals; k++) { free(maux->als[k]); maux->als[k] = strdup(line->d.allele[k]); ma1->map[k] = k; maux->cnt[k] = 1; int var_type = bcf_has_variant_type(line, k, VCF_ANY); if ( args->collapse==COLLAPSE_SNP_INS_DEL ) var_type &= ~VCF_INDEL; maux->als_types[k] = var_type ? var_type<<1 : ref_mask; } return; } // normalize alleles maux->als = merge_alleles(line->d.allele, line->n_allele, ma1->map, maux->als, &maux->nals, &maux->mals); if ( !maux->als ) error("Failed to merge alleles at %s:%"PRId64" in %s\n",maux->chr,(int64_t) line->pos+1,reader->fname); hts_expand0(int, maux->nals, maux->ncnt, maux->cnt); hts_expand0(int, maux->nals, maux->mals_types, maux->als_types); for (k=1; kn_allele; k++) { int ik = ma1->map[k]; int var_type = bcf_has_variant_type(line, k, VCF_ANY); if ( args->collapse==COLLAPSE_SNP_INS_DEL ) var_type &= ~VCF_INDEL; maux->als_types[ik] = var_type ? var_type<<1 : ref_mask; maux->cnt[ik]++; // how many times an allele appears in the files } maux->cnt[0]++; } /* Determine which lines remain to be merged across readers at the current position and are compatible given the -m criteria. This is indicated by maux1_t.skip: 0=compatible, SKIP_DONE=the record is done, SKIP_DIFF=not compatible and will be included next time. At the same time count how many times is each allele present across the readers and records so that we can prioritize the records with the same alleles to come first. In the end maximum one record at a time can be selected from each reader and that witll be done in stage_line(). The function maux_reset already initialized structures for this position, so here each reader comes with the beg,end indexes that point to records with the same maux_t.pos position. */ int can_merge(args_t *args) { bcf_srs_t *files = args->files; maux_t *maux = args->maux; gvcf_aux_t *gaux = maux->gvcf; char *id = NULL, ref = 'N'; int i,j, ntodo = 0; for (i=0; inals; i++) { free(maux->als[i]); maux->als[i] = NULL; maux->cnt[i] = 0; } maux->var_types = maux->nals = 0; // In this loop we do the following: // - remember the first encountered ID if matching by ID // - count the number of unprocessed records at this position // - collect all variant types at this position. This is to be able to perform -m matching and // print SNVs first, then indels, then gVCF blocks // - init the 'skip' variable to SKIP_DIFF for each record that has not been used yet for (i=0; inreaders; i++) { buffer_t *buf = &maux->buf[i]; buf->var_types = 0; if ( gaux && gaux[i].active ) // active gvcf block { buf->rec[buf->beg].skip = SKIP_DIFF; maux->var_types |= ref_mask; buf->var_types |= ref_mask; buf->rec[buf->beg].var_types = ref_mask; continue; } // for gvcf: find out REF at this position if ( buf->beg < buf->end && ref=='N' ) ref = buf->lines[buf->beg]->d.allele[0][0]; for (j=buf->beg; jend; j++) { if ( buf->rec[j].skip & SKIP_DONE ) continue; buf->rec[j].skip = SKIP_DIFF; ntodo++; bcf1_t *line = buf->lines[j]; if ( args->merge_by_id && !id ) { id = line->d.id; continue; } // set ID when merging by id if ( !buf->rec[j].var_types ) { int var_type = bcf_has_variant_types(line, VCF_ANY, bcf_match_overlap); if ( var_type < 0 ) error("bcf_has_variant_types() failed."); if ( args->collapse==COLLAPSE_SNP_INS_DEL ) { // need to distinguish between ins and del so strip the VCF_INDEL flag var_type &= ~VCF_INDEL; } var_type = var_type ? var_type<<1 : ref_mask; if ( args->do_gvcf && is_gvcf_block(line) ) var_type |= ref_mask; buf->rec[j].var_types = var_type; } maux->var_types |= buf->rec[j].var_types; buf->var_types |= buf->rec[j].var_types; } } if ( !ntodo ) return 0; int selected_types = 0; // In this loop we select from each reader compatible candidate lines. // (i.e. SNPs or indels). Go through all files and all lines at this // position and normalize relevant alleles. // REF-only sites may be associated with both SNPs and indels. for (i=0; inreaders; i++) { buffer_t *buf = &maux->buf[i]; if ( gaux && gaux[i].active ) { // gVCF records inherited from an upstream gVCF block have incorrect or missing allele and position gaux[i].line->d.allele[0][0] = ref; gaux[i].line->pos = maux->pos; maux_update_alleles(args, i, buf->beg); selected_types |= ref_mask; continue; } for (j=buf->beg; jend; j++) { if ( buf->rec[j].skip & SKIP_DONE ) continue; bcf1_t *line = buf->lines[j]; // ptr to reader's buffer or gvcf buffer int line_types = buf->rec[j].var_types; // select relevant lines if ( args->merge_by_id ) { if ( strcmp(id,line->d.id) ) continue; // matching by ID and it does not match the selected record } else if ( selected_types && !types_compatible(args,selected_types,buf,j) ) continue; else { // First time here, choosing the first line: prioritize SNPs when available in the -m snps,both modes if ( (args->collapse&COLLAPSE_SNPS || args->collapse==COLLAPSE_NONE) // asked to merge SNVs into multiallelics && (maux->var_types&snp_mask) // there are SNVs at the current position && !(buf->rec[j].var_types&(snp_mask|ref_mask)) // and this record is not a SNV nor ref ) continue; } selected_types |= line_types; buf->rec[j].skip = 0; // the j-th record from i-th reader can be included. Final decision will be made in stage_line maux_update_alleles(args, i, j); } } return 1; } /* Select records that have the same alleles; the input ordering of indels must not matter. Multiple VCF lines can be emitted from this loop. We expect only very few alleles and not many records with the same position in the buffers, therefore the nested loops should not slow us much. */ void stage_line(args_t *args) { bcf_srs_t *files = args->files; maux_t *maux = args->maux; // Take the most frequent allele present in multiple files, REF and gVCF_REF is skipped. int i,j,k,icnt = -1; for (i=1; inals; i++) { if ( maux->als_types[i] & ref_mask ) continue; if ( icnt==-1 || maux->cnt[icnt] < maux->cnt[i] ) icnt = i; } int selected_type = icnt>0 ? maux->als_types[icnt] : ref_mask; int nout = 0; for (i=0; inreaders; i++) { buffer_t *buf = &maux->buf[i]; buf->cur = -1; if ( buf->beg >= buf->end ) continue; // No lines in the buffer at this site // find lines with the same allele for (j=buf->beg; jend; j++) { if ( buf->rec[j].skip ) { int is_gvcf = maux->gvcf && maux->gvcf[i].active ? 1 : 0; if ( !is_gvcf && is_gvcf_block(buf->lines[j]) ) is_gvcf = 1; if ( !is_gvcf ) continue; // done or not compatible } if ( args->merge_by_id ) break; // if merging by ID and the line is compatible, the this is THE line // skip if the reader has a record that matches the most frequent allele and this record is not it if ( (selected_type & buf->var_types) && !(selected_type & buf->rec[j].var_types) ) continue; // if the reader does not have the most frequent allele type but is a ref, accept if ( !(selected_type & buf->var_types) && (buf->rec[j].var_types & ref_mask) ) break; if ( selected_type==ref_mask ) break; // accept if the record has the most frequent allele for (k=0; klines[j]->n_allele; k++) if ( icnt==buf->rec[j].map[k] ) break; if ( klines[j]->n_allele ) break; } if ( j>=buf->end ) { // no matching allele found in this file if ( args->collapse==COLLAPSE_NONE ) continue; // exact matching requested, skip // choose something compatible to create a multiallelic site given the -m criteria for (j=buf->beg; jend; j++) { if ( buf->rec[j].skip ) continue; // done or not compatible if ( args->collapse&COLLAPSE_ANY ) break; // anything can be merged int line_type = buf->rec[j].var_types; if ( maux->var_types&snp_mask && line_type&snp_mask && (args->collapse&COLLAPSE_SNPS) ) break; if ( maux->var_types&indel_mask && line_type&indel_mask && (args->collapse&COLLAPSE_INDELS) ) break; if ( maux->var_types&ins_mask && line_type&ins_mask && (args->collapse&COLLAPSE_SNP_INS_DEL) ) break; if ( maux->var_types&del_mask && line_type&del_mask && (args->collapse&COLLAPSE_SNP_INS_DEL) ) break; if ( line_type&ref_mask ) { if ( maux->var_types&snp_mask && (args->collapse&COLLAPSE_SNPS) ) break; if ( maux->var_types&indel_mask && (args->collapse&COLLAPSE_INDELS) ) break; if ( maux->var_types&ins_mask && (args->collapse&COLLAPSE_SNP_INS_DEL) ) break; if ( maux->var_types&del_mask && (args->collapse&COLLAPSE_SNP_INS_DEL) ) break; if ( maux->var_types&ref_mask ) break; } else if ( maux->var_types&ref_mask ) { if ( line_type&snp_mask && (args->collapse&COLLAPSE_SNPS) ) break; if ( line_type&indel_mask && (args->collapse&COLLAPSE_INDELS) ) break; if ( line_type&ins_mask && (args->collapse&COLLAPSE_SNP_INS_DEL) ) break; if ( line_type&del_mask && (args->collapse&COLLAPSE_SNP_INS_DEL) ) break; } } } if ( jend ) { // found a suitable line for merging buf->cur = j; } } // debug_maux(args); // Mark lines staged for merging as finished so that they are ignored next time for (i=0; inreaders; i++) { buffer_t *buf = &maux->buf[i]; if ( buf->cur == -1 ) continue; buf->rec[buf->cur].skip = SKIP_DONE; nout++; } assert( nout ); } void merge_line(args_t *args) { bcf1_t *out = args->out_line; merge_chrom2qual(args, out); if ( args->regs && !regidx_overlap(args->regs,args->maux->chr,out->pos,out->pos+out->rlen-1,NULL) ) return; merge_filter(args, out); merge_info(args, out); if ( args->do_gvcf ) bcf_update_info_int32(args->out_hdr, out, "END", NULL, 0); merge_format(args, out); int iunseen; if ( args->trim_star_allele && (out->n_allele > 2 || args->trim_star_allele > 1) && (iunseen=get_unseen_allele(out)) && iunseen>0 ) { // the unobserved star allele should be trimmed, either it is variant site or trimming of all sites was requested kbitset_t *rm_set = kbs_init(out->n_allele); kbs_insert(rm_set, iunseen); if ( bcf_remove_allele_set(args->out_hdr,out,rm_set) ) error("[%s] Error: failed to trim the unobserved allele at %s:%"PRIhts_pos"\n",__func__,bcf_seqname(args->out_hdr,out),out->pos+1); kbs_destroy(rm_set); } if ( bcf_write1(args->out_fh, args->out_hdr, out)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); bcf_clear1(out); } void bcf_hdr_append_version(bcf_hdr_t *hdr, int argc, char **argv, const char *cmd) { kstring_t str = {0,0,0}; int e = 0; if (ksprintf(&str,"##%sVersion=%s+htslib-%s\n", cmd, bcftools_version(), hts_version()) < 0) goto fail; if (bcf_hdr_append(hdr,str.s) < 0) goto fail; str.l = 0; e |= ksprintf(&str,"##%sCommand=%s", cmd, argv[0]) < 0; int i; for (i=1; inhrec; i++) { if ( hdr->hrec[i]->type!=BCF_HL_FMT ) continue; j = bcf_hrec_find_key(hdr->hrec[i],"ID"); if ( j<0 ) continue; char *key = hdr->hrec[i]->vals[j]; int id = bcf_hdr_id2int(hdr, BCF_DT_ID, key); assert( id>=0 ); int localize = 0; if ( bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_G ) localize = 1; if ( bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_A ) localize = 1; if ( bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_R ) localize = 1; if ( !localize ) continue; args->tmps.l = 0; uint32_t e = 0, nout = 0; e |= ksprintf(&args->tmps, "##%s=<", hdr->hrec[i]->key) < 0; for (j=0; jhrec[i]->nkeys; j++) { if ( !strcmp("IDX",hdr->hrec[i]->keys[j]) ) continue; if ( nout ) e |= kputc(',',&args->tmps) < 0; if ( !strcmp("ID",hdr->hrec[i]->keys[j]) ) e |= ksprintf(&args->tmps,"%s=L%s", hdr->hrec[i]->keys[j], hdr->hrec[i]->vals[j]) < 0; else if ( !strcmp("Number",hdr->hrec[i]->keys[j]) ) e |= ksprintf(&args->tmps,"Number=.") < 0; else if ( !strcmp("Description",hdr->hrec[i]->keys[j]) && hdr->hrec[i]->vals[j][0]=='"' ) e |= ksprintf(&args->tmps,"Description=\"Localized field: %s", hdr->hrec[i]->vals[j]+1) < 0; else e |= ksprintf(&args->tmps,"%s=%s", hdr->hrec[i]->keys[j], hdr->hrec[i]->vals[j]) < 0; nout++; } e |= ksprintf(&args->tmps,">\n") < 0; if ( e ) error("Failed to format the header line for %s\n", key); nstr++; hts_expand(char*,nstr,mstr,str); str[nstr-1] = strdup(args->tmps.s); } if ( !nstr ) return; bcf_hdr_append(hdr,"##FORMAT="); for (i=0; ioutput_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->n_threads ) hts_set_opt(args->out_fh, HTS_OPT_THREAD_POOL, args->files->p); //hts_set_threads(args->out_fh, args->n_threads); args->out_hdr = bcf_hdr_init("w"); if ( args->header_fname ) { if ( bcf_hdr_set(args->out_hdr,args->header_fname) ) error("Could not read/parse the header: %s\n", args->header_fname); } else { int i; for (i=0; ifiles->nreaders; i++) { char buf[24]; snprintf(buf,sizeof buf,"%d",i+1); merge_headers(args->out_hdr, args->files->readers[i].header,buf,args->force_samples); } if ( args->local_alleles ) hdr_add_localized_tags(args, args->out_hdr); if (args->record_cmd_line) bcf_hdr_append_version(args->out_hdr, args->argc, args->argv, "bcftools_merge"); if (bcf_hdr_sync(args->out_hdr) < 0) error_errno("[%s] Failed to update header", __func__); } info_rules_init(args); missing_rules_init(args); bcf_hdr_set_version(args->out_hdr, bcf_hdr_get_version(args->files->readers[0].header)); if ( bcf_hdr_write(args->out_fh, args->out_hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( args->header_only ) { bcf_hdr_destroy(args->out_hdr); if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); return; } else if ( init_index2(args->out_fh,args->out_hdr,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); args->vcmp = vcmp_init(); args->maux = maux_init(args); args->out_line = bcf_init1(); args->tmph = kh_init(strdict); int *rid_tab = calloc(args->maux->n, sizeof(*rid_tab)); if (!rid_tab) error("[%s:%d] Could not allocate %zu bytes\n", __FILE__, __LINE__, args->maux->n*sizeof(*rid_tab)); while ( bcf_sr_next_line(args->files) ) { // output cached gVCF blocks which end before the new record if ( args->do_gvcf ) gvcf_flush(args,0); maux_reset(args->maux, rid_tab); // determine which of the new records are gvcf blocks if ( args->do_gvcf ) gvcf_stage(args, args->maux->pos); while ( can_merge(args) ) { stage_line(args); merge_line(args); } clean_buffer(args); // debug_state(args); } free(rid_tab); if ( args->do_gvcf ) gvcf_flush(args,1); info_rules_destroy(args); missing_rules_destroy(args); maux_destroy(args->maux); bcf_hdr_destroy(args->out_hdr); if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname?args->output_fname:"stdout"); bcf_destroy1(args->out_line); kh_destroy(strdict, args->tmph); if ( args->tmps.m ) free(args->tmps.s); if ( args->vcmp ) vcmp_destroy(args->vcmp); } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Merge multiple VCF/BCF files from non-overlapping sample sets to create one multi-sample file.\n"); fprintf(stderr, " Note that only records from different files can be merged, never from the same file. For\n"); fprintf(stderr, " \"vertical\" merge take a look at \"bcftools norm\" instead.\n"); fprintf(stderr, "Usage: bcftools merge [options] [...]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " --force-no-index Merge unindexed files, synonymous to --no-index\n"); fprintf(stderr, " --force-samples Resolve duplicate sample names\n"); fprintf(stderr, " --force-single Run even if there is only one file on input\n"); fprintf(stderr, " --print-header Print only the merged header and exit\n"); fprintf(stderr, " --use-header FILE Use the provided header\n"); fprintf(stderr, " -0 --missing-to-ref Assume genotypes at missing sites are 0/0\n"); fprintf(stderr, " -f, --apply-filters LIST Require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); fprintf(stderr, " -F, --filter-logic x|+ Remove filters if some input is PASS (\"x\"), or apply all filters (\"+\") [+]\n"); fprintf(stderr, " -g, --gvcf -|REF.FA Merge gVCF blocks, INFO/END tag is expected. Implies -i QS:sum,MinDP:min,MIN_DP:min,I16:sum,IDV:max,IMF:max -M PL:max,AD:0\n"); fprintf(stderr, " -i, --info-rules TAG:METHOD,.. Rules for merging INFO fields (method is one of sum,avg,min,max,join) or \"-\" to turn off the default [DP:sum,DP4:sum]\n"); fprintf(stderr, " -l, --file-list FILE Read file names from the file\n"); fprintf(stderr, " -L, --local-alleles INT If more than INT alt alleles are encountered, drop FMT/PL and output LAA+LPL instead; 0=unlimited [0]\n"); fprintf(stderr, " -m, --merge STRING[*|**] Allow multiallelic records for snps,indels,both,snp-ins-del,all,none,id,*,**; see man page for details [both]\n"); fprintf(stderr, " -M, --missing-rules TAG:METHOD Rules for replacing missing values in numeric vectors (.,0,max) when unknown allele <*> is not present [.]\n"); fprintf(stderr, " --no-index Merge unindexed files, the same chromosomal order is required and -r/-R are not allowed\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " --threads INT Use multithreading with INT worker threads [0]\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfmerge(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->files = bcf_sr_init(); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->collapse = COLLAPSE_BOTH; args->clevel = -1; int regions_is_file = 0; int regions_overlap = 1; static struct option loptions[] = { {"help",no_argument,NULL,'h'}, {"merge",required_argument,NULL,'m'}, {"local-alleles",required_argument,NULL,'L'}, {"gvcf",required_argument,NULL,'g'}, {"file-list",required_argument,NULL,'l'}, {"missing-to-ref",no_argument,NULL,'0'}, {"apply-filters",required_argument,NULL,'f'}, {"use-header",required_argument,NULL,1}, {"print-header",no_argument,NULL,2}, {"force-samples",no_argument,NULL,3}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,4}, {"info-rules",required_argument,NULL,'i'}, {"missing-rules",required_argument,NULL,'M'}, {"no-version",no_argument,NULL,8}, {"no-index",no_argument,NULL,10}, {"force-no-index",no_argument,NULL,10}, {"force-single",no_argument,NULL,12}, {"filter-logic",required_argument,NULL,'F'}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "hm:f:r:R:o:O:i:M:l:g:F:0L:W::",loptions,NULL)) >= 0) { switch (c) { case 'L': args->local_alleles = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --local-alleles %s\n", optarg); if ( args->local_alleles < 1 ) error("Error: \"--local-alleles %s\" makes no sense, expected value bigger or equal than 1\n", optarg); break; case 'F': if ( !strcmp(optarg,"+") ) args->filter_logic = FLT_LOGIC_ADD; else if ( !strcmp(optarg,"x") ) args->filter_logic = FLT_LOGIC_REMOVE; else error("Filter logic not recognised: %s\n", optarg); break; case '0': args->missing_to_ref = 1; break; case 'g': args->do_gvcf = 1; if ( strcmp("-",optarg) ) { args->gvcf_fai = fai_load(optarg); if ( !args->gvcf_fai ) error("Failed to load the fai index: %s\n", optarg); } break; case 'l': args->file_list = optarg; break; case 'i': args->info_rules = optarg; break; case 'M': args->missing_rules_str = optarg; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'm': { int len = strlen(optarg); if ( optarg[len-1]=='*' ) { args->trim_star_allele++; len--; } if ( optarg[len-1]=='*' ) { args->trim_star_allele++; len--; } if ( optarg[len-1]==',' ) len--; args->collapse = COLLAPSE_NONE; if ( !strncmp(optarg,"snp-ins-del",len) ) args->collapse = COLLAPSE_SNP_INS_DEL|COLLAPSE_SNPS; else if ( !strncmp(optarg,"snps",len) ) args->collapse |= COLLAPSE_SNPS; else if ( !strncmp(optarg,"indels",len) ) args->collapse |= COLLAPSE_INDELS; else if ( !strncmp(optarg,"id",len) ) { args->collapse = COLLAPSE_NONE; args->merge_by_id = 1; } else if ( !strncmp(optarg,"any",len) ) args->collapse |= COLLAPSE_ANY; else if ( !strncmp(optarg,"all",len) ) args->collapse |= COLLAPSE_ANY; else if ( !strncmp(optarg,"both",len) ) args->collapse |= COLLAPSE_BOTH; else if ( !strncmp(optarg,"none",len) ) args->collapse = COLLAPSE_NONE; else error("The -m type \"%s\" is not recognised.\n", optarg); break; } case 'f': args->files->apply_filters = optarg; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 1 : args->header_fname = optarg; break; case 2 : args->header_only = 1; break; case 3 : args->force_samples = 1; break; case 4 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 10 : args->no_index = 1; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 12 : args->force_single = 1; break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } if ( argc==optind && !args->file_list ) usage(); if ( args->no_index ) { if ( args->regions_list ) error("Error: cannot combine --no-index with -r/-R\n"); bcf_sr_set_opt(args->files,BCF_SR_ALLOW_NO_IDX); } else bcf_sr_set_opt(args->files,BCF_SR_REQUIRE_IDX); if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); if ( regions_is_file ) args->regs = regidx_init(args->regions_list,NULL,NULL,sizeof(char*),NULL); else { args->regs = regidx_init(NULL,regidx_parse_reg,NULL,sizeof(char*),NULL); if ( regidx_insert_list(args->regs,args->regions_list,',') !=0 ) error("Could not parse the regions: %s\n", args->regions_list); regidx_insert(args->regs,NULL); } if ( !args->regs ) error("Could not parse the regions: %s\n", args->regions_list); args->regs_itr = regitr_init(args->regs); } if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); while (optindfiles, argv[optind]) ) error("Failed to open %s: %s\n", argv[optind],bcf_sr_strerror(args->files->errnum)); optind++; } if ( args->file_list ) { int nfiles, i; char **files = hts_readlines(args->file_list, &nfiles); if ( !files ) error("Failed to read from %s\n", args->file_list); for (i=0;ifiles, files[i]) ) error("Failed to open %s: %s\n", files[i],bcf_sr_strerror(args->files->errnum)); for (i=0; ifiles->nreaders ) usage(); if ( args->files->nreaders==1 && !args->force_single ) error("Expected two or more files to merge, got only one. Use --force-single to proceed anyway\n"); merge_vcf(args); bcf_sr_destroy(args->files); if ( args->regs ) regidx_destroy(args->regs); if ( args->regs_itr ) regitr_destroy(args->regs_itr); if ( args->gvcf_fai ) fai_destroy(args->gvcf_fai); free(args); return 0; } bcftools-1.21/vcfnorm.c000066400000000000000000003331221467060157400151040ustar00rootroot00000000000000/* vcfnorm.c -- Left-align and normalize indels. Copyright (C) 2013-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "rbuf.h" #include "abuf.h" #include "gff.h" #include "regidx.h" #include "filter.h" #define CHECK_REF_EXIT 1 #define CHECK_REF_WARN 2 #define CHECK_REF_SKIP 4 #define CHECK_REF_FIX 8 #define MROWS_SPLIT 1 #define MROWS_MERGE 2 // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 // for -m+, mapping from allele indexes of a single input record // to allele indexes of output record typedef struct { int nals, mals, *map; } map_t; // primitive comparison of two records' alleles via hashes; normalized alleles assumed typedef struct { int n; // number of alleles char *ref, *alt; void *hash; // str2int hash } cmpals1_t; typedef struct { cmpals1_t *cmpals; int ncmpals, mcmpals; } cmpals_t; typedef struct { char *tseq, *seq; int mseq; bcf1_t **lines, **tmp_lines, **mrows, *mrow_out; int ntmp_lines, mtmp_lines, nmrows, mmrows, mrows_first; map_t *maps; // mrow map for each buffered record char **als; int mmaps, nals, mals; uint8_t *tmp_arr1, *tmp_arr2, *diploid; int32_t *int32_arr; int ntmp_arr1, ntmp_arr2, nint32_arr; kstring_t *tmp_str; kstring_t *tmp_als, *tmp_sym, tmp_kstr; int ntmp_als, ntmp_sym; rbuf_t rbuf; int buf_win; // maximum distance between two records to consider int aln_win; // the realignment window size (maximum repeat size) bcf_srs_t *files; // using the synced reader only for -r option bcf_hdr_t *hdr, *out_hdr; cmpals_t cmpals_in, cmpals_out; faidx_t *fai; struct { int tot, set, swap; } nref; char **argv, *output_fname, *ref_fname, *vcf_fname, *region, *targets; int argc, rmdup, output_type, n_threads, check_ref, strict_filter, do_indels, clevel; int nchanged, nskipped, nsplit, njoined, ntotal, nfilter, mrows_op, mrows_collapse, parsimonious; int record_cmd_line, force, force_warned, keep_sum_ad; abuf_t *abuf; abuf_opt_t atomize; int use_star_allele, ma_use_ref_allele; char *old_rec_tag; htsFile *out; char *index_fn; int write_index, gff_verbosity; int right_align; char *gff_fname; gff_t *gff; regidx_t *idx_tscript; regitr_t *itr_tscript; int (*cmp_func)(const void *aptr, const void *bptr); char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE int filter_pass; filter_t *filter; } args_t; static inline int replace_iupac_codes(char *seq, int nseq) { // Replace ambiguity codes with N for now, it awaits to be seen what the VCF spec codifies in the end int i, n = 0; for (i=0; id.allele[0]); int i,j, maxlen = reflen, len; for (i=1; in_allele; i++) { int len = strlen(line->d.allele[i]); if ( maxlen < len ) maxlen = len; } char *ref = faidx_fetch_seq(args->fai, (char*)bcf_seqname(args->hdr,line), line->pos, line->pos+maxlen-1, &len); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); replace_iupac_codes(ref,len); args->nref.tot++; // is the REF different? If not, we are done if ( !strncasecmp(line->d.allele[0],ref,reflen) ) { free(ref); return; } // is the REF allele missing? if ( reflen==1 && line->d.allele[0][0]=='.' ) { line->d.allele[0][0] = ref[0]; args->nref.set++; free(ref); bcf_update_alleles(args->out_hdr,line,(const char**)line->d.allele,line->n_allele); return; } // does REF or ALT contain non-standard bases? int has_non_acgtn = 0; for (i=0; in_allele; i++) { if ( line->d.allele[i][0]=='<' ) continue; has_non_acgtn += replace_iupac_codes(line->d.allele[i],strlen(line->d.allele[i])); } if ( has_non_acgtn ) { args->nref.set++; bcf_update_alleles(args->out_hdr,line,(const char**)line->d.allele,line->n_allele); if ( !strncasecmp(line->d.allele[0],ref,reflen) ) { free(ref); return; } } // does the REF allele contain N's ? int fix = 0; for (i=0; id.allele[0][i]!='N' ) continue; if ( ref[i]=='N' ) continue; line->d.allele[0][i] = ref[i]; fix++; for (j=1; jn_allele; j++) { int len = strlen(line->d.allele[j]); if ( len <= i || line->d.allele[j][i]!='N' ) continue; line->d.allele[j][i] = ref[i]; fix++; } } if ( fix ) { args->nref.set++; bcf_update_alleles(args->out_hdr,line,(const char**)line->d.allele,line->n_allele); if ( !strncasecmp(line->d.allele[0],ref,reflen) ) { free(ref); return; } } // is it swapped? for (i=1; in_allele; i++) { int len = strlen(line->d.allele[i]); if ( !strncasecmp(line->d.allele[i],ref,len) ) break; } kstring_t str = {0,0,0}; if ( i==line->n_allele ) // none of the alternate alleles matches the reference { args->nref.set++; kputsn(ref,reflen,&str); for (i=1; in_allele; i++) { kputc(',',&str); kputs(line->d.allele[i],&str); } bcf_update_alleles_str(args->out_hdr,line,str.s); free(ref); free(str.s); return; } // one of the alternate alleles matches the reference, assume it's a simple swap kputs(line->d.allele[i],&str); for (j=1; jn_allele; j++) { kputc(',',&str); if ( j==i ) kputs(line->d.allele[0],&str); else kputs(line->d.allele[j],&str); } bcf_update_alleles_str(args->out_hdr,line,str.s); args->nref.swap++; free(ref); free(str.s); // swap genotypes int ntmp = args->ntmp_arr1 / sizeof(int32_t); // reuse tmp_arr declared as uint8_t int ngts = bcf_get_genotypes(args->hdr, line, &args->tmp_arr1, &ntmp); args->ntmp_arr1 = ntmp * sizeof(int32_t); int32_t *gts = (int32_t*) args->tmp_arr1; int ni = 0; for (j=0; jout_hdr,line,gts,ngts); // update AC int nac = bcf_get_info_int32(args->hdr, line, "AC", &args->tmp_arr1, &ntmp); args->ntmp_arr1 = ntmp * sizeof(int32_t); if ( i <= nac ) { int32_t *ac = (int32_t*)args->tmp_arr1; ac[i-1] = ni; bcf_update_info_int32(args->out_hdr, line, "AC", ac, nac); } } static void fix_dup_alt(args_t *args, bcf1_t *line) { // update alleles, create a mapping between old and new indexes hts_expand(uint8_t,line->n_allele,args->ntmp_arr1,args->tmp_arr1); args->tmp_arr1[0] = 0; // ref always unchanged int i, j, nals = line->n_allele, nals_ori = line->n_allele; for (i=1, j=1; in_allele; i++) { if ( strcasecmp(line->d.allele[0],line->d.allele[i]) ) { args->tmp_arr1[i] = j++; continue; } args->tmp_arr1[i] = 0; nals--; } for (i=1, j=1; in_allele; i++) { if ( !args->tmp_arr1[i] ) continue; line->d.allele[j++] = line->d.allele[i]; } bcf_update_alleles(args->out_hdr, line, (const char**)line->d.allele, nals); // update genotypes int ntmp = args->ntmp_arr2 / sizeof(int32_t); // reuse tmp_arr declared as uint8_t int ngts = bcf_get_genotypes(args->hdr, line, &args->tmp_arr2, &ntmp); args->ntmp_arr2 = ntmp * sizeof(int32_t); int32_t *gts = (int32_t*) args->tmp_arr2; int changed = 0; for (i=0; itmp_arr1[ial] ) continue; int ial_new = ialtmp_arr1[ial] : 0; gts[i] = bcf_gt_is_phased(gts[i]) ? bcf_gt_phased(ial_new) : bcf_gt_unphased(ial_new); changed = 1; } if ( changed ) bcf_update_genotypes(args->out_hdr,line,gts,ngts); } static void set_old_rec_tag(args_t *args, bcf1_t *dst, bcf1_t *src, int ialt) { if ( !args->old_rec_tag ) return; // only update if the tag is not present already, there can be multiple normalization steps int i, id = bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, args->old_rec_tag); bcf_unpack(dst, BCF_UN_INFO); for (i=0; in_info; i++) { bcf_info_t *inf = &dst->d.info[i]; if ( inf && inf->key == id ) return; } args->tmp_kstr.l = 0; ksprintf(&args->tmp_kstr,"%s|%"PRIhts_pos"|%s|",bcf_seqname(args->hdr,src),src->pos+1,src->d.allele[0]); for (i=1; in_allele; i++) { kputs(src->d.allele[i],&args->tmp_kstr); if ( i+1n_allele ) kputc(',',&args->tmp_kstr); } if ( ialt>0 ) { kputc('|',&args->tmp_kstr); kputw(ialt,&args->tmp_kstr); } if ( (bcf_update_info_string(args->out_hdr, dst, args->old_rec_tag, args->tmp_kstr.s))!=0 ) error("An error occurred while updating INFO/%s\n",args->old_rec_tag); } static int is_left_align(args_t *args, bcf1_t *line) { if ( args->right_align ) return 0; if ( !args->gff ) return 1; const char *chr = bcf_seqname(args->hdr,line); if ( !strncasecmp("chr",chr,3) ) chr += 3; // strip 'chr' prefix, that's what we requested the GFF reader to do if ( !regidx_overlap(args->idx_tscript,chr,line->pos,line->pos+line->rlen, args->itr_tscript) ) return 1; // if there are two conflicting overlapping transcripts, go with the default left-alignment int has_fwd = 0; while ( regitr_overlap(args->itr_tscript) ) { gf_tscript_t *tr = regitr_payload(args->itr_tscript, gf_tscript_t*); if ( tr->strand==STRAND_FWD ) has_fwd = 1; if ( tr->strand==STRAND_REV ) return 1; } // either no hit at all (then left-align) or everything was on fwd strand (then right-align) return has_fwd ? 0 : 1; } static hts_pos_t realign_left(args_t *args, bcf1_t *line) { // trim from right char *ref = NULL; int i; hts_pos_t nref=0, new_pos = line->pos; kstring_t *als = args->tmp_als; while (1) { // is the rightmost base identical in all alleles? int min_len = als[0].l; for (i=1; in_allele; i++) { if ( toupper(als[0].s[ als[0].l-1 ]) != toupper(als[i].s[ als[i].l-1 ]) ) break; if ( als[i].l < min_len ) min_len = als[i].l; } if ( i!=line->n_allele ) break; // there are differences, cannot be trimmed if ( min_len<=1 && new_pos==0 ) break; int pad_from_left = 0; for (i=0; in_allele; i++) // trim all alleles { als[i].l--; if ( !als[i].l ) pad_from_left = 1; } if ( pad_from_left ) { // extend all alleles to the left by aln_win bases (unless close to the chr start). // Extra bases will be trimmed from the left after this loop is done int npad = new_pos >= args->aln_win ? args->aln_win : new_pos; free(ref); ref = faidx_fetch_seq64(args->fai, bcf_seqname(args->hdr,line), new_pos-npad, new_pos-1, &nref); if ( !ref ) error("faidx_fetch_seq64 failed at %s:%"PRId64"\n", bcf_seqname(args->hdr,line), (int64_t) new_pos-npad+1); replace_iupac_codes(ref,nref); for (i=0; in_allele; i++) { ks_resize(&als[i], als[i].l + npad); if ( als[i].l ) memmove(als[i].s+npad,als[i].s,als[i].l); memcpy(als[i].s,ref,npad); als[i].l += npad; } new_pos -= npad; } } free(ref); // trim from left int ntrim_left = 0; while (1) { // is the first base identical in all alleles? int min_len = als[0].l - ntrim_left; for (i=1; in_allele; i++) { if ( toupper(als[0].s[ntrim_left]) != toupper(als[i].s[ntrim_left]) ) break; if ( min_len > als[i].l - ntrim_left ) min_len = als[i].l - ntrim_left; } if ( i!=line->n_allele || min_len<=1 ) break; // there are differences, cannot be trimmed ntrim_left++; } if ( ntrim_left ) { for (i=0; in_allele; i++) { memmove(als[i].s,als[i].s+ntrim_left,als[i].l-ntrim_left); als[i].l -= ntrim_left; } new_pos += ntrim_left; } return new_pos; } static hts_pos_t realign_right(args_t *args, bcf1_t *line) { char *ref = NULL; int i; hts_pos_t new_pos = line->pos, nref = 0; kstring_t *als = args->tmp_als; // trim from left int ntrim_left = 0, npad_right = line->rlen, has_indel = 0; while (1) { // is the leftmost base identical in all alleles? int min_len = als[0].l - ntrim_left; for (i=1; in_allele; i++) { if ( als[0].l!=als[i].l ) has_indel = 1; if ( toupper(als[0].s[ntrim_left]) != toupper(als[i].s[ntrim_left]) ) break; if ( min_len > als[i].l - ntrim_left ) min_len = als[i].l - ntrim_left; } if ( i!=line->n_allele ) break; // there are differences, cannot be trimmed further ntrim_left++; if ( min_len<=1 ) // pad from the right { free(ref); ref = faidx_fetch_seq64(args->fai, bcf_seqname(args->hdr,line), line->pos + npad_right, line->pos + npad_right + args->aln_win, &nref); if ( !ref ) error("faidx_fetch_seq64 failed at %s:%"PRIhts_pos"\n",bcf_seqname(args->hdr,line), new_pos + ntrim_left); npad_right += args->aln_win; replace_iupac_codes(ref,nref); for (i=0; in_allele; i++) kputs(ref, &als[i]); } } ntrim_left -= has_indel; if ( ntrim_left > 0 ) { for (i=0; in_allele; i++) { memmove(als[i].s, als[i].s + ntrim_left, als[i].l - ntrim_left); als[i].l -= ntrim_left; } new_pos += ntrim_left; } free(ref); // trim from right while (1) { // is the last base identical in all alleles? int min_len = als[0].l; for (i=1; in_allele; i++) { if ( toupper(als[0].s[ als[0].l-1 ]) != toupper(als[i].s[ als[i].l-1 ]) ) break; if ( min_len > als[i].l ) min_len = als[i].l; } if ( i!=line->n_allele || min_len<=1 ) break; // there are differences, cannot be trimmed more for (i=0; in_allele; i++) { als[i].l--; als[i].s[als[i].l]=0; } } return new_pos; } #define ERR_DUP_ALLELE -2 #define ERR_REF_MISMATCH -1 #define ERR_OK 0 #define ERR_SYMBOLIC 1 #define ERR_SPANNING_DELETION 2 static int realign(args_t *args, bcf1_t *line) { bcf_unpack(line, BCF_UN_STR); // Sanity check REF int i, nref, reflen = strlen(line->d.allele[0]); char *ref = faidx_fetch_seq(args->fai, (char*)args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos, line->pos+reflen-1, &nref); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", args->hdr->id[BCF_DT_CTG][line->rid].key, (int64_t) line->pos+1); seq_to_upper(ref,0); replace_iupac_codes(ref,nref); // any non-ACGT character in fasta ref is replaced with N // does VCF REF contain non-standard bases? if ( has_non_acgtn(line->d.allele[0],reflen) ) { if ( args->check_ref==CHECK_REF_EXIT ) error("Non-ACGTN reference allele at %s:%"PRId64" .. REF_SEQ:'%s' vs VCF:'%s'\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1,ref,line->d.allele[0]); if ( args->check_ref & CHECK_REF_WARN ) fprintf(stderr,"NON_ACGTN_REF\t%s\t%"PRId64"\t%s\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1,line->d.allele[0]); free(ref); return ERR_REF_MISMATCH; } if ( strcasecmp(ref,line->d.allele[0]) ) { if ( args->check_ref==CHECK_REF_EXIT ) error("Reference allele mismatch at %s:%"PRId64" .. REF_SEQ:'%s' vs VCF:'%s'\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1,ref,line->d.allele[0]); if ( args->check_ref & CHECK_REF_WARN ) fprintf(stderr,"REF_MISMATCH\t%s\t%"PRId64"\t%s\t%s\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1,line->d.allele[0],ref); free(ref); return ERR_REF_MISMATCH; } free(ref); ref = NULL; if ( line->n_allele == 1 ) // a REF { if ( line->rlen > 1 ) { line->d.allele[0][1] = 0; bcf_update_alleles(args->out_hdr,line,(const char**)line->d.allele,line->n_allele); } return ERR_OK; } if ( bcf_get_variant_types(line)==VCF_BND ) return ERR_SYMBOLIC; // breakend, not an error // make a copy of each allele for trimming hts_expand0(kstring_t,line->n_allele,args->ntmp_als,args->tmp_als); // the actual sequence to realign hts_expand0(kstring_t,line->n_allele,args->ntmp_sym,args->tmp_sym); // the original symbolic allele strings to output kstring_t *als = args->tmp_als; kstring_t *sym = args->tmp_sym; int symbolic_alts = 1; for (i=0; in_allele; i++) { sym[i].l = 0; if ( line->d.allele[i][0]=='<' ) { // symbolic allele, only and will be realigned // TODO: there should be check for symbolic allele length. If too big, perhaps should not attempt realignment int32_t sv_len = 0; if ( !strncmp("d.allele[i],4) ) sv_len = -line->rlen; else if ( !strncmp("d.allele[i],4) ) { if ( bcf_get_info_int32(args->hdr,line,"SVLEN",&args->int32_arr,&args->nint32_arr)==1 ) sv_len = args->int32_arr[0]; } if ( !sv_len ) return ERR_SYMBOLIC; als[i].l = 0; if ( sv_len<0 ) { // del, expand REF and replace ALT, for example, replace "REF=C ALT=" with "REF=CAT ALT=C" if ( nref < line->rlen ) { free(ref); reflen = line->rlen; ref = faidx_fetch_seq(args->fai, (char*)args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos, line->pos+reflen-1, &nref); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", args->hdr->id[BCF_DT_CTG][line->rid].key, (int64_t) line->pos+1); seq_to_upper(ref,0); replace_iupac_codes(ref,nref); // any non-ACGT character in fasta ref is replaced with N als[0].l = 0; kputs(ref, &als[0]); } kputsn(als[0].s,1,&als[i]); } else // sv_len>0 { // dup, replace "REF=C ALT=" with "REF=C ALT=CAT" free(ref); ref = faidx_fetch_seq(args->fai, (char*)args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos, line->pos+sv_len, &nref); if ( !ref ) error("faidx_fetch_seq failed at %s:%"PRId64"\n", args->hdr->id[BCF_DT_CTG][line->rid].key, (int64_t) line->pos+1); seq_to_upper(ref,0); replace_iupac_codes(ref,nref); // any non-ACGT character in fasta ref is replaced with N kputs(ref,&als[i]); } kputs(line->d.allele[i],&sym[i]); // preserve the symbolic allele string continue; } if ( i>0 ) symbolic_alts = 0; if ( line->d.allele[i][0]=='*' ) return ERR_SPANNING_DELETION; // spanning deletion if ( has_non_acgtn(line->d.allele[i],line->shared.l) ) { if ( args->check_ref==CHECK_REF_EXIT ) error("Non-ACGTN alternate allele at %s:%"PRId64" .. VCF:'%s'\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1,line->d.allele[i]); if ( args->check_ref & CHECK_REF_WARN ) fprintf(stderr,"NON_ACGTN_ALT\t%s\t%"PRId64"\t%s\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1,line->d.allele[i]); return ERR_REF_MISMATCH; } als[i].l = 0; kputs(line->d.allele[i], &als[i]); seq_to_upper(als[i].s,0); if ( i>0 && als[i].l==als[0].l && !strcasecmp(als[0].s,als[i].s) ) return ERR_DUP_ALLELE; } free(ref); ref = NULL; // which direction are we aligning? int left_align = is_left_align(args, line); hts_pos_t new_pos; if ( left_align ) new_pos = realign_left(args, line); else new_pos = realign_right(args, line); // Have the alleles changed? Consider could have expanded the REF allele. In that // case it must be trimmed, however the new REF length must reflect the entire length. als[0].s[ als[0].l ] = 0; // for strcmp to work int new_reflen = strlen(als[0].s); if ( symbolic_alts ) { als[0].l = 1; als[0].s[ als[0].l ] = 0; } if ( new_pos==line->pos && !strcasecmp(line->d.allele[0],als[0].s) ) return ERR_OK; set_old_rec_tag(args, line, line, 0); // Create new block of alleles and update args->tmp_kstr.l = 0; for (i=0; in_allele; i++) { if (i>0) kputc(',',&args->tmp_kstr); if ( sym[i].l ) kputs(sym[i].s,&args->tmp_kstr); else kputsn(als[i].s,als[i].l,&args->tmp_kstr); } args->tmp_kstr.s[ args->tmp_kstr.l ] = 0; bcf_update_alleles_str(args->out_hdr,line,args->tmp_kstr.s); args->nchanged++; // Update INFO/END if necessary if ( (new_pos!=line->pos || reflen!=new_reflen) && bcf_get_info_int32(args->hdr, line, "END", &args->int32_arr, &args->nint32_arr)==1 ) { // bcf_update_alleles_str() messed up rlen because line->pos changed. This will be fixed by bcf_update_info_int32() line->pos = new_pos; args->int32_arr[0] = line->pos + new_reflen; bcf_update_info_int32(args->out_hdr, line, "END", args->int32_arr, 1); } line->pos = new_pos; return ERR_OK; } static void split_info_numeric(args_t *args, bcf1_t *src, bcf_info_t *info, int ialt, bcf1_t *dst) { #define BRANCH_NUMERIC(type,type_t,is_vector_end,is_missing) \ { \ const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); \ int ntmp = args->ntmp_arr1 / sizeof(type_t); \ int ret = bcf_get_info_##type(args->hdr,src,tag,&args->tmp_arr1,&ntmp); \ args->ntmp_arr1 = ntmp * sizeof(type_t); \ assert( ret>0 ); \ type_t *vals = (type_t*) args->tmp_arr1; \ int len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); \ if ( len==BCF_VL_A ) \ { \ if ( ret!=src->n_allele-1 ) \ { \ if ( args->force && !args->force_warned ) \ { \ fprintf(stderr, \ "Warning: wrong number of fields in INFO/%s at %s:%"PRId64", expected %d, found %d\n" \ " (This warning is printed only once.)\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele-1,ret); \ args->force_warned = 1; \ } \ if ( args->force ) \ { \ bcf_update_info_##type(args->out_hdr,dst,tag,NULL,0); \ return; \ } \ error("Error: wrong number of fields in INFO/%s at %s:%"PRId64", expected %d, found %d. Use --force to proceed anyway.\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele-1,ret); \ } \ bcf_update_info_##type(args->out_hdr,dst,tag,vals+ialt,1); \ } \ else if ( len==BCF_VL_R ) \ { \ if ( ret!=src->n_allele ) \ { \ if ( args->force && !args->force_warned ) \ { \ fprintf(stderr, \ "Warning: wrong number of fields in INFO/%s at %s:%"PRId64", expected %d, found %d\n" \ " (This warning is printed only once.)\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele,ret); \ args->force_warned = 1; \ } \ if ( args->force ) \ { \ bcf_update_info_##type(args->out_hdr,dst,tag,NULL,0); \ return; \ } \ error("Error: wrong number of fields in INFO/%s at %s:%"PRId64", expected %d, found %d. Use --force to proceed anyway.\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele,ret); \ } \ if ( args->keep_sum_ad >= 0 && args->keep_sum_ad==info->key ) \ { \ int j; \ for (j=1; jlen; j++) \ if ( j!=ialt+1 && !(is_missing) && !(is_vector_end) ) vals[0] += vals[j]; \ vals[1] = vals[ialt+1]; \ } \ else \ { \ if ( ialt!=0 ) vals[1] = vals[ialt+1]; \ } \ bcf_update_info_##type(args->out_hdr,dst,tag,vals,2); \ } \ else if ( len==BCF_VL_G ) \ { \ if ( ret!=src->n_allele*(src->n_allele+1)/2 ) \ { \ if ( args->force && !args->force_warned ) \ { \ fprintf(stderr, \ "Warning: wrong number of fields in INFO/%s at %s:%"PRId64", expected %d, found %d\n" \ " (This warning is printed only once.)\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele*(src->n_allele+1)/2,ret); \ args->force_warned = 1; \ } \ if ( args->force ) \ { \ bcf_update_info_##type(args->out_hdr,dst,tag,NULL,0); \ return; \ } \ error("Error: wrong number of fields in INFO/%s at %s:%"PRId64", expected %d, found %d. Use --force to proceed anyway.\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele*(src->n_allele+1)/2,ret); \ } \ if ( ialt!=0 ) \ { \ vals[1] = vals[bcf_alleles2gt(0,ialt+1)]; \ vals[2] = vals[bcf_alleles2gt(ialt+1,ialt+1)]; \ } \ bcf_update_info_##type(args->out_hdr,dst,tag,vals,3); \ } \ else \ bcf_update_info_##type(args->out_hdr,dst,tag,vals,ret); \ } switch (bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key)) { case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, vals[j]==bcf_int32_vector_end, vals[j]==bcf_int32_missing); break; case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_is_vector_end(vals[j]), bcf_float_is_missing(vals[j])); break; } #undef BRANCH_NUMERIC } // Find nth field in a comma-separated list in src and move it to dst. // The dst and src memory areas may overlap, end points just after the last valid src // character. // On success returns pointer to the end of the parsed field and increments ndst by the // number of memmoved characters. Returns NULL if the field was not found. static inline char *string_move_nth(char *dst, char *src, char *end, int nth, size_t *ndst) { if ( src>=end ) return NULL; char *ss = src, *se = src; int j = 0; while ( *se && se<(end) ) { if ( *se==',' ) { if ( j==nth ) break; j++; ss = se+1; } se++; } if ( j!=nth ) return NULL; if ( ss>=end ) return NULL; if ( !*ss ) return NULL; int n = se - ss; memmove((dst),ss,n); *ndst += n; return se; } static void split_info_string(args_t *args, bcf1_t *src, bcf_info_t *info, int ialt, bcf1_t *dst) { const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); int ret = bcf_get_info_string(args->hdr,src,tag,&args->tmp_arr1,&args->ntmp_arr1); assert( ret>0 ); kstring_t str; str.m = args->ntmp_arr1; str.l = ret; str.s = (char*) args->tmp_arr1; int len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); if ( len==BCF_VL_A ) { char *end = str.s + str.l; char *tmp = str.s; str.l = 0; tmp = string_move_nth(str.s,tmp,end,ialt,&str.l); if ( !tmp ) str.l = 1, str.s[0] = '.'; kputc_(0,&str); bcf_update_info_string(args->out_hdr,dst,tag,str.s); } else if ( len==BCF_VL_R ) { char *end = str.s + str.l; char *tmp = str.s; str.l = 0; tmp = string_move_nth(str.s,tmp,end,0,&str.l); if ( tmp ) { kputc_(',',&str); tmp = string_move_nth(str.s+str.l,tmp+1,end,ialt,&str.l); // ialt is 0-based index to ALT } if ( !tmp ) str.l = 1, str.s[0] = '.'; kputc_(0,&str); bcf_update_info_string(args->out_hdr,dst,tag,str.s); } else if ( len==BCF_VL_G ) { int i0a = bcf_alleles2gt(0,ialt+1), iaa = bcf_alleles2gt(ialt+1,ialt+1); char *end = str.s + str.l; char *tmp = str.s; str.l = 0; tmp = string_move_nth(str.s,tmp,end,0,&str.l); if ( tmp ) { kputc_(',',&str); tmp = string_move_nth(str.s+str.l,tmp+1,end,i0a-1,&str.l); } if ( tmp ) { kputc_(',',&str); tmp = string_move_nth(str.s+str.l,tmp+1,end,iaa-i0a-1,&str.l); } if ( !tmp ) str.l = 1, str.s[0] = '.'; kputc_(0,&str); bcf_update_info_string(args->out_hdr,dst,tag,str.s); } else bcf_update_info_string(args->out_hdr,dst,tag,str.s); if ( args->ntmp_arr1 < str.m ) { args->ntmp_arr1 = str.m; args->tmp_arr1 = (uint8_t*)str.s; } } static void split_info_flag(args_t *args, bcf1_t *src, bcf_info_t *info, int ialt, bcf1_t *dst) { const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); int ret = bcf_get_info_flag(args->hdr,src,tag,&args->tmp_arr1,&args->ntmp_arr1); bcf_update_info_flag(args->out_hdr,dst,tag,NULL,ret); } static void split_format_genotype(args_t *args, bcf1_t *src, bcf_fmt_t *fmt, int ialt, bcf1_t *dst) { int ntmp = args->ntmp_arr1 / 4; int ngts = bcf_get_genotypes(args->hdr,src,&args->tmp_arr1,&ntmp); args->ntmp_arr1 = ntmp * 4; assert( ngts >0 ); int32_t *gt = (int32_t*) args->tmp_arr1; int i, j, nsmpl = bcf_hdr_nsamples(args->hdr); ngts /= nsmpl; for (i=0; ima_use_ref_allele ) gt[j] = bcf_gt_unphased(0) | bcf_gt_is_phased(gt[j]); // set to REF else gt[j] = bcf_gt_missing | bcf_gt_is_phased(gt[j]); // set to missing } gt += ngts; } bcf_update_genotypes(args->out_hdr,dst,args->tmp_arr1,ngts*nsmpl); } static void split_format_numeric(args_t *args, bcf1_t *src, bcf_fmt_t *fmt, int ialt, bcf1_t *dst) { #define BRANCH_NUMERIC(type,type_t,is_vector_end,is_missing,set_vector_end,set_missing) \ { \ const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id); \ int ntmp = args->ntmp_arr1 / sizeof(type_t); \ int nvals = bcf_get_format_##type(args->hdr,src,tag,&args->tmp_arr1,&ntmp); \ args->ntmp_arr1 = ntmp * sizeof(type_t); \ assert( nvals>0 ); \ type_t *vals = (type_t *) args->tmp_arr1; \ int len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); \ int i,j, nsmpl = bcf_hdr_nsamples(args->hdr); \ if ( nvals==nsmpl ) /* all values are missing */ \ { \ bcf_update_format_##type(args->out_hdr,dst,tag,vals,nsmpl); \ return; \ } \ if ( len==BCF_VL_A ) \ { \ if ( nvals!=(src->n_allele-1)*nsmpl ) \ { \ if ( args->force && !args->force_warned ) \ { \ fprintf(stderr, \ "Warning: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d, found %d. Removing the field.\n" \ " (This warning is printed only once.)\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,(src->n_allele-1)*nsmpl,nvals); \ args->force_warned = 1; \ } \ if ( args->force ) \ { \ bcf_update_format_##type(args->out_hdr,dst,tag,NULL,0); \ return; \ } \ error("Error: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d, found %d. Use --force to proceed anyway.\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,(src->n_allele-1)*nsmpl,nvals); \ } \ nvals /= nsmpl; \ type_t *src_vals = vals, *dst_vals = vals; \ for (i=0; iout_hdr,dst,tag,vals,nsmpl); \ } \ else if ( len==BCF_VL_R ) \ { \ if ( nvals!=src->n_allele*nsmpl ) \ { \ if ( args->force && !args->force_warned ) \ { \ fprintf(stderr, \ "Warning: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d, found %d. Removing the field.\n" \ " (This warning is printed only once.)\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,(src->n_allele-1)*nsmpl,nvals); \ args->force_warned = 1; \ } \ if ( args->force ) \ { \ bcf_update_format_##type(args->out_hdr,dst,tag,NULL,0); \ return; \ } \ error("Error: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d, found %d. Use --force to proceed anyway.\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele*nsmpl,nvals); \ } \ nvals /= nsmpl; \ type_t *src_vals = vals, *dst_vals = vals; \ if ( args->keep_sum_ad >= 0 && args->keep_sum_ad==fmt->id ) \ { \ for (i=0; iout_hdr,dst,tag,vals,nsmpl*2); \ } \ else if ( len==BCF_VL_G ) \ { \ if ( nvals!=src->n_allele*(src->n_allele+1)/2*nsmpl && nvals!=src->n_allele*nsmpl ) \ { \ if ( args->force && !args->force_warned ) \ { \ fprintf(stderr, \ "Warning: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d, found %d. Removing the field.\n" \ " (This warning is printed only once.)\n", \ tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,(src->n_allele-1)*nsmpl,nvals); \ args->force_warned = 1; \ } \ if ( args->force ) \ { \ bcf_update_format_##type(args->out_hdr,dst,tag,NULL,0); \ return; \ } \ error("Error at %s:%"PRId64", the tag %s has wrong number of fields. Use --force to proceed anyway.\n", \ bcf_seqname(args->hdr,src),(int64_t) src->pos+1,bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id)); \ } \ nvals /= nsmpl; \ int all_haploid = nvals==src->n_allele ? 1 : 0; \ type_t *src_vals = vals, *dst_vals = vals; \ for (i=0; iout_hdr,dst,tag,vals,all_haploid ? nsmpl*2 : nsmpl*3); \ } \ else \ bcf_update_format_##type(args->out_hdr,dst,tag,vals,nvals); \ } switch (bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id)) { case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, src_vals[isrc]==bcf_int32_vector_end, src_vals[isrc]==bcf_int32_missing, dst_vals[idst]=bcf_int32_vector_end, dst_vals[idst]=bcf_int32_missing); break; case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_is_vector_end(src_vals[isrc]), bcf_float_is_missing(src_vals[isrc]), bcf_float_set_vector_end(dst_vals[idst]), bcf_float_set_missing(src_vals[idst])); break; } #undef BRANCH_NUMERIC } static void squeeze_format_char(char *str, int src_blen, int dst_blen, int n) { int i, isrc = 0, idst = 0; for (i=0; ihdr,BCF_DT_ID,fmt->id); int ret = bcf_get_format_char(args->hdr,src,tag,&args->tmp_arr1,&args->ntmp_arr1); if ( !ret ) return; // all values can be empty, leave out the tag, no need to panic assert( ret>0 ); int nsmpl = bcf_hdr_nsamples(args->hdr); int blen = ret/nsmpl; // per-sample field length assert( blen>0 ); kstring_t str; str.m = args->ntmp_arr1; str.s = (char*) args->tmp_arr1; str.l = ret; int tag_len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); if ( tag_len==BCF_VL_A ) { int i, maxlen = 0; char *ptr = str.s; for (i=0; iout_hdr,dst,tag,str.s,nsmpl*maxlen); } else if ( tag_len==BCF_VL_R ) { int i, maxlen = 0; char *ptr = str.s; for (i=0; iout_hdr,dst,tag,str.s,nsmpl*maxlen); } else if ( tag_len==BCF_VL_G ) { int i, maxlen = 0, i0a = bcf_alleles2gt(0,ialt+1), iaa = bcf_alleles2gt(ialt+1,ialt+1); char *ptr = str.s; for (i=0; in_allele*(src->n_allele+1)/2 && nfields!=src->n_allele ) { if ( args->force && !args->force_warned ) { fprintf(stderr, "Warning: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d or %d, found %d. Removing the field.\n" " (This warning is printed only once.)\n", tag,bcf_seqname(args->hdr,src),(int64_t)src->pos+1,src->n_allele*(src->n_allele+1)/2,src->n_allele,nfields); args->force_warned = 1; } if ( args->force ) { bcf_update_format_char(args->out_hdr,dst,tag,NULL,0); return; } error("Error: wrong number of fields in FMT/%s at %s:%"PRId64", expected %d or %d, found %d. Use --force to proceed anyway.\n", tag,bcf_seqname(args->hdr,src),(int64_t) src->pos+1,src->n_allele*(src->n_allele+1)/2,src->n_allele,nfields); } char *tmp = ptr; char *end = ptr + blen; size_t len = 0; tmp = string_move_nth(ptr,tmp,end,0,&len); if ( nfields==src->n_allele ) // haploid { if ( tmp ) { ptr[len++] = ','; tmp = string_move_nth(ptr+len,tmp+1,end,ialt,&len); } } else // diploid { if ( tmp ) { ptr[len++] = ','; tmp = string_move_nth(ptr+len,tmp+1,end,i0a-1,&len); } if ( tmp ) { ptr[len++] = ','; tmp = string_move_nth(ptr+len,tmp+1,end,iaa-i0a-1,&len); } } if ( !tmp ) ptr[0] = '.', len = 1; if ( maxlen < len ) maxlen = len; while (lenout_hdr,dst,tag,str.s,nsmpl*maxlen); } else bcf_update_format_char(args->out_hdr,dst,tag,str.s,str.l); } static void split_multiallelic_to_biallelics(args_t *args, bcf1_t *line) { int i; bcf_unpack(line, BCF_UN_ALL); // Init the target biallelic lines args->ntmp_lines = line->n_allele-1; if ( args->mtmp_lines < args->ntmp_lines ) { args->tmp_lines = (bcf1_t **)realloc(args->tmp_lines,sizeof(bcf1_t*)*args->ntmp_lines); for (i=args->mtmp_lines; intmp_lines; i++) args->tmp_lines[i] = NULL; args->mtmp_lines = args->ntmp_lines; } kstring_t tmp = {0,0,0}; kputs(line->d.allele[0], &tmp); kputc(',', &tmp); int rlen = tmp.l; int gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); for (i=0; intmp_lines; i++) // for each ALT allele { if ( !args->tmp_lines[i] ) args->tmp_lines[i] = bcf_init1(); bcf1_t *dst = args->tmp_lines[i]; bcf_clear(dst); dst->rid = line->rid; dst->pos = line->pos; dst->qual = line->qual; // Not quite sure how to handle IDs, they can be assigned to a specific // ALT. For now we leave the ID unchanged for all. bcf_update_id(args->out_hdr, dst, line->d.id ? line->d.id : "."); tmp.l = rlen; kputs(line->d.allele[i+1],&tmp); bcf_update_alleles_str(args->out_hdr,dst,tmp.s); if ( line->d.n_flt ) bcf_update_filter(args->hdr, dst, line->d.flt, line->d.n_flt); int j; for (j=0; jn_info; j++) { bcf_info_t *info = &line->d.info[j]; int type = bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key); if ( type==BCF_HT_INT || type==BCF_HT_REAL ) split_info_numeric(args, line, info, i, dst); else if ( type==BCF_HT_FLAG ) split_info_flag(args, line, info, i, dst); else split_info_string(args, line, info, i, dst); } set_old_rec_tag(args, dst, line, i + 1); // 1-based indexes dst->n_sample = line->n_sample; for (j=0; jn_fmt; j++) { bcf_fmt_t *fmt = &line->d.fmt[j]; int type = bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id); if ( fmt->id==gt_id ) split_format_genotype(args, line, fmt, i, dst); else if ( type==BCF_HT_INT || type==BCF_HT_REAL ) split_format_numeric(args, line, fmt, i, dst); else split_format_string(args, line, fmt, i, dst); } } free(tmp.s); } // Enlarge FORMAT array containing nsmpl samples each with nals_ori values // to accommodate nvals values for each sample, filling the gaps with missing // values. Works also for INFO arrays, with nsmpl set to 1. #define ENLARGE_ARRAY(type_t,set_missing,arr,narr_bytes,nsmpl,nvals_ori,nvals) \ { \ int nbytes_new = (nsmpl)*(nvals)*sizeof(type_t); \ hts_expand(uint8_t,nbytes_new,narr_bytes,arr); \ int ismpl, k; \ for (ismpl=nsmpl-1; ismpl>=0; ismpl--) \ { \ type_t *dst_ptr = ((type_t*)arr) + ismpl*(nvals); \ type_t *src_ptr = ((type_t*)arr) + ismpl*nvals_ori; \ memmove(dst_ptr,src_ptr,sizeof(type_t)*nvals_ori); \ for (k=nvals_ori; khdr,BCF_DT_ID,info->key); \ int ntmp = args->ntmp_arr1 / sizeof(type_t); \ int nvals_ori = bcf_get_info_##type(args->hdr,lines[0],tag,&args->tmp_arr1,&ntmp); \ args->ntmp_arr1 = ntmp * sizeof(type_t); \ assert( nvals_ori>0 ); \ type_t *vals = (type_t*) args->tmp_arr1, *vals2; \ int i,k,len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); \ if ( len==BCF_VL_A ) \ { \ if (nvals_ori!=lines[0]->n_allele - 1) \ error("vcfnorm: number of fields in first record at position %s:%"PRId64" for INFO tag %s not as expected [found: %d vs expected:%d]\n", bcf_seqname(args->hdr,lines[0]),(int64_t) lines[0]->pos+1, tag, nvals_ori, lines[0]->n_allele-1); \ int nvals = dst->n_allele - 1; \ ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,1,nvals_ori,nvals); \ vals = (type_t*) args->tmp_arr1; \ for (i=1; intmp_arr2 / sizeof(type_t); \ int nvals2 = bcf_get_info_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ if (nvals2<0) continue; /* info tag does not exist in this record, skip */ \ args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ if (nvals2!=lines[i]->n_allele-1) \ error("vcfnorm: could not merge INFO tag %s at position %s:%"PRId64"\n", tag, bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1); \ vals2 = (type_t*) args->tmp_arr2; \ for (k=0; kmaps[i].map[k+1] - 1 ] = vals2[k]; \ } \ } \ bcf_update_info_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals); \ } \ else if ( len==BCF_VL_R ) \ { \ if (nvals_ori!=lines[0]->n_allele) \ error("vcfnorm: number of fields in first record at position %s:%"PRId64" for INFO tag %s not as expected [found: %d vs expected:%d]\n", bcf_seqname(args->hdr,lines[0]),(int64_t) lines[0]->pos+1, tag, nvals_ori, lines[0]->n_allele); \ int nvals = dst->n_allele; \ ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,1,nvals_ori,nvals); \ vals = (type_t*) args->tmp_arr1; \ for (i=1; intmp_arr2 / sizeof(type_t); \ int nvals2 = bcf_get_info_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ if (nvals2<0) continue; /* info tag does not exist in this record, skip */ \ args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ if (nvals2!=lines[i]->n_allele) \ error("vcfnorm: could not merge INFO tag %s at position %s:%"PRId64"\n", tag, bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1); \ vals2 = (type_t*) args->tmp_arr2; \ for (k=0; kmaps[i].map[k] ] = vals2[k]; \ } \ } \ bcf_update_info_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals); \ } \ else if ( len==BCF_VL_G ) \ { \ /* expecting diploid gt in INFO */ \ if (nvals_ori!=lines[0]->n_allele*(lines[0]->n_allele+1)/2) { \ fprintf(stderr, "todo: merge Number=G INFO fields for haploid sites\n"); \ error("vcfnorm: number of fields in first record at position %s:%"PRId64" for INFO tag %s not as expected [found: %d vs expected:%d]\n", bcf_seqname(args->hdr,lines[0]),(int64_t) lines[0]->pos+1, tag, nvals_ori, lines[0]->n_allele*(lines[0]->n_allele+1)/2); \ } \ int nvals = dst->n_allele*(dst->n_allele+1)/2; \ ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,1,nvals_ori,nvals); \ vals = (type_t*) args->tmp_arr1; \ for (i=1; intmp_arr2 / sizeof(type_t); \ int nvals2 = bcf_get_info_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ if (nvals2<0) continue; /* info tag does not exist in this record, skip */ \ args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ if (nvals2!=lines[i]->n_allele*(lines[i]->n_allele+1)/2) \ error("vcfnorm: could not merge INFO tag %s at position %s:%"PRId64"\n", tag, bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1); \ vals2 = (type_t*) args->tmp_arr2; \ int ia,ib; \ k = 0; \ for (ia=0; ian_allele; ia++) \ { \ for (ib=0; ib<=ia; ib++) \ { \ if ( is_vector_end ) break; \ int l = bcf_alleles2gt(args->maps[i].map[ia],args->maps[i].map[ib]); \ vals[l] = vals2[k]; \ k++; \ } \ } \ } \ bcf_update_info_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals); \ } \ else \ bcf_update_info_##type(args->out_hdr,dst,tag,vals,nvals_ori); \ } switch (bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key)) { case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, dst_ptr[k]=bcf_int32_missing, vals2[k]==bcf_int32_vector_end); break; case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_set_missing(dst_ptr[k]), bcf_float_is_vector_end(vals2[k])); break; } #undef BRANCH_NUMERIC } static void merge_info_flag(args_t *args, bcf1_t **lines, int nlines, bcf_info_t *info, bcf1_t *dst) { const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); int ret = bcf_get_info_flag(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); bcf_update_info_flag(args->out_hdr,dst,tag,NULL,ret); } int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst); // see vcfmerge.c static void merge_info_string(args_t *args, bcf1_t **lines, int nlines, bcf_info_t *info, bcf1_t *dst) { const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); kstring_t str; str.m = args->ntmp_arr1; str.l = 0; str.s = (char*) args->tmp_arr1; int i, j, len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); if ( len==BCF_VL_A || len==BCF_VL_R ) { int jfrom = len==BCF_VL_A ? 1 : 0; kputc('.',&str); for (i=jfrom+1; in_allele; i++) kputs(",.",&str); for (i=0; ihdr,lines[i],tag); if (!src) continue; for (j=jfrom; jn_allele; j++) copy_string_field((char*)src->vptr, j-jfrom, src->len, &str, args->maps[i].map[j]-jfrom); } str.s[str.l] = 0; args->tmp_arr1 = (uint8_t*) str.s; args->ntmp_arr1 = str.m; bcf_update_info_string(args->out_hdr,dst,tag,str.s); } else if ( len==BCF_VL_G ) { int ngts = dst->n_allele*(dst->n_allele+1)/2; kputc('.',&str); for (i=1; ihdr,lines[i],tag); if (!src) continue; int iori, jori, kori = 0; for (iori=0; iorin_allele; iori++) { int inew = args->maps[i].map[iori]; for (jori=0; jori<=iori; jori++) { int jnew = args->maps[i].map[jori]; int knew = bcf_alleles2gt(inew,jnew); copy_string_field((char*)src->vptr,kori,src->len,&str,knew); kori++; } } } str.s[str.l] = 0; args->tmp_arr1 = (uint8_t*) str.s; args->ntmp_arr1 = str.m; bcf_update_info_string(args->out_hdr,dst,tag,str.s); } else { bcf_get_info_string(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); bcf_update_info_string(args->out_hdr,dst,tag,args->tmp_arr1); } } static int gt_array_grow_ploidy(args_t *args, uint8_t **tmp_arr, int *ntmp_arr, int ngt_ori, int ngt_new, int nsmpl) { *ntmp_arr = 4*ngt_new*nsmpl; int32_t *ptr = (int32_t*)realloc(*tmp_arr,*ntmp_arr); if ( !ptr ) error("Error: failed to allocate %d bytes\n",*ntmp_arr); *tmp_arr = (uint8_t*) ptr; int i,j; for (i=nsmpl-1; i>=0; i--) { int32_t *src = ptr + i*ngt_ori; int32_t *dst = ptr + i*ngt_new; for (j=ngt_new; j>ngt_ori; j--) dst[j-1] = bcf_int32_vector_end; for (j=ngt_ori; j>0; j--) dst[j-1] = src[j-1]; } return ngt_new; } static void merge_format_genotype(args_t *args, bcf1_t **lines, int nlines, bcf_fmt_t *fmt, bcf1_t *dst) { // reusing int8_t arrays as int32_t arrays int ntmp = args->ntmp_arr1 / 4; int ngts = bcf_get_genotypes(args->hdr,lines[0],&args->tmp_arr1,&ntmp); args->ntmp_arr1 = ntmp * 4; assert( ngts >0 ); int nsmpl = bcf_hdr_nsamples(args->hdr); ngts /= nsmpl; int i, j, k,k2; for (i=1; intmp_arr2 / 4; int ngts2 = bcf_get_genotypes(args->hdr,lines[i],&args->tmp_arr2,&ntmp2); args->ntmp_arr2 = ntmp2 * 4; ngts2 /= nsmpl; int ploidy_changed = ngts - ngts2; if ( ngts < ngts2 ) ngts = gt_array_grow_ploidy(args,&args->tmp_arr1,&args->ntmp_arr1,ngts,ngts2,nsmpl); if ( ngts > ngts2 ) ngts2 = gt_array_grow_ploidy(args,&args->tmp_arr2,&args->ntmp_arr2,ngts2,ngts,nsmpl); int32_t *gt = (int32_t*) args->tmp_arr1; // the first, destination line int32_t *gt2 = (int32_t*) args->tmp_arr2; // one of the subsequent lines, i.e. the source line for (j=0; j=args->maps[i].nals ) error("Error at %s:%"PRId64": incorrect allele index %d\n",bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1,ial2); // The destination allele int ial = args->maps[i].map[ial2]; if ( gt[k2]==bcf_int32_vector_end || bcf_gt_is_missing(gt[k2]) || !bcf_gt_allele(gt[k2]) ) gt[k2] = (gt[k2]!=bcf_int32_vector_end && bcf_gt_is_phased(gt[k2])) ? bcf_gt_phased(ial) : bcf_gt_unphased(ial); else { // conflict, the first line has non-zero allele, use the old way, possibly disrupt the phasing for (k=0; kout_hdr,dst,args->tmp_arr1,ngts*nsmpl); } static int diploid_to_haploid(int size, int nsmpl, int nals, uint8_t *vals) { int i, dsrc = size*nals*(nals+1)/2, ddst = size*nals; uint8_t *src_ptr = vals + dsrc, *dst_ptr = vals + ddst; for (i=1; ihdr,BCF_DT_ID,fmt->id); \ int ntmp = args->ntmp_arr1 / sizeof(type_t); \ int nvals_ori = bcf_get_format_##type(args->hdr,lines[0],tag,&args->tmp_arr1,&ntmp); \ args->ntmp_arr1 = ntmp * sizeof(type_t); \ assert( nvals_ori>0 ); \ type_t *vals2, *vals = (type_t *) args->tmp_arr1; \ int len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); \ int i, j, k, nsmpl = bcf_hdr_nsamples(args->hdr); \ nvals_ori /= nsmpl; \ if ( len==BCF_VL_A ) \ { \ int nvals = dst->n_allele - 1; \ ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,nsmpl,nvals_ori,nvals); \ for (i=1; intmp_arr2 / sizeof(type_t); \ int nvals2 = bcf_get_format_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ if (nvals2<0) continue; /* format tag does not exist in this record, skip */ \ args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ nvals2 /= nsmpl; \ if (nvals2!=lines[i]->n_allele-1) \ error("vcfnorm: could not merge FORMAT tag %s at position %s:%"PRId64"\n", tag, bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1); \ vals = (type_t*) args->tmp_arr1; \ vals2 = (type_t*) args->tmp_arr2; \ for (j=0; jmaps[i].map[k+1] - 1 ] = vals2[k]; \ } \ vals += nvals; \ vals2 += nvals2; \ } \ } \ bcf_update_format_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals*nsmpl); \ } \ else if ( len==BCF_VL_R ) \ { \ int nvals = dst->n_allele; \ ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,nsmpl,nvals_ori,nvals); \ for (i=1; intmp_arr2 / sizeof(type_t); \ int nvals2 = bcf_get_format_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ if (nvals2<0) continue; /* format tag does not exist in this record, skip */ \ args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ nvals2 /= nsmpl; \ if (nvals2!=lines[i]->n_allele) \ error("vcfnorm: could not merge FORMAT tag %s at position %s:%"PRId64"\n", tag, bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1); \ vals = (type_t*) args->tmp_arr1; \ vals2 = (type_t*) args->tmp_arr2; \ for (j=0; jmaps[i].map[k] ] = vals2[k]; \ } \ vals += nvals; \ vals2 += nvals2; \ } \ } \ bcf_update_format_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals*nsmpl); \ } \ else if ( len==BCF_VL_G ) \ { \ /* which samples are diploid */ \ memset(args->diploid,0,nsmpl); \ int all_haploid = 1; \ if ( nvals_ori > lines[0]->n_allele ) /* line possibly diploid */ \ { \ vals2 = (type_t*) args->tmp_arr1; \ int ndiploid = lines[0]->n_allele*(lines[0]->n_allele+1)/2; \ for (i=0; idiploid[i] ) \ { \ for (k=0; kdiploid[i] = 1; all_haploid = 0; }\ } \ vals2 += nvals_ori; \ } \ } \ int nvals = dst->n_allele*(dst->n_allele+1)/2; \ ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,nsmpl,nvals_ori,nvals); \ for (i=1; intmp_arr2 / sizeof(type_t); \ int nvals2 = bcf_get_format_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ if (nvals2<0) continue; /* format tag does not exist in this record, skip */ \ args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ nvals2 /= nsmpl; \ int ndiploid = lines[i]->n_allele*(lines[i]->n_allele+1)/2; \ int line_diploid = nvals2==ndiploid ? 1 : 0; \ if (!(nvals2==1 || nvals2==lines[i]->n_allele || nvals2==lines[i]->n_allele*(lines[i]->n_allele+1)/2)) \ error("vcfnorm: could not merge FORMAT tag %s at position %s:%"PRId64"\n", tag, bcf_seqname(args->hdr,lines[i]),(int64_t) lines[i]->pos+1); \ vals = (type_t*) args->tmp_arr1; \ vals2 = (type_t*) args->tmp_arr2; \ for (j=0; jdiploid[j] ) { args->diploid[j] = 1; all_haploid = 0; } \ if ( !smpl_diploid ) \ { \ for (k=0; kn_allele; k++) vals[args->maps[i].map[k]] = vals2[k]; \ } \ else \ { \ k = 0; \ int ia,ib; \ for (ia=0; ian_allele; ia++) \ { \ for (ib=0; ib<=ia; ib++) \ { \ int l = bcf_alleles2gt(args->maps[i].map[ia],args->maps[i].map[ib]); \ vals[l] = vals2[k]; \ k++; \ } \ } \ } \ vals += nvals; \ vals2 += nvals2; \ } \ } \ if ( all_haploid ) \ nvals = diploid_to_haploid(sizeof(type_t),nsmpl,dst->n_allele,args->tmp_arr1); \ else \ {\ k = dst->n_allele;\ vals2 = (type_t*) args->tmp_arr1;\ for (i=0; idiploid[i] ) set_vector_end;\ vals2 += nvals;\ }\ }\ bcf_update_format_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals*nsmpl); \ } \ else \ bcf_update_format_##type(args->out_hdr,dst,tag,args->tmp_arr1,nvals_ori*nsmpl); \ } switch (bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id)) { case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, dst_ptr[k]=bcf_int32_missing, vals2[k]==bcf_int32_vector_end, vals2[k]=bcf_int32_vector_end); break; case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_set_missing(dst_ptr[k]), bcf_float_is_vector_end(vals2[k]), bcf_float_set_vector_end(vals2[k])); break; } #undef BRANCH_NUMERIC } static void merge_format_string(args_t *args, bcf1_t **lines, int nlines, bcf_fmt_t *fmt, bcf1_t *dst) { const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id); int i, j, k, len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); if ( len!=BCF_VL_A && len!=BCF_VL_R && len!=BCF_VL_G ) { int nret = bcf_get_format_char(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); bcf_update_format_char(args->out_hdr,dst,tag,args->tmp_arr1,nret); return; } int nsmpl = bcf_hdr_nsamples(args->hdr); for (i=0; itmp_str[i].l = 0; if ( len==BCF_VL_A || len==BCF_VL_R ) { int jfrom = len==BCF_VL_A ? 1 : 0; for (i=0; itmp_str[i]; kputc('.',tmp); for (k=jfrom+1; kn_allele; k++) kputs(",.",tmp); } for (i=0; ihdr,lines[i],tag,&args->tmp_arr1,&args->ntmp_arr1); if (nret<0) continue; /* format tag does not exist in this record, skip */ nret /= nsmpl; for (k=0; ktmp_str[k]; char *src = (char*)args->tmp_arr1 + k*nret; for (j=jfrom; jn_allele; j++) copy_string_field(src, j-jfrom, nret, tmp, args->maps[i].map[j]-jfrom); } } } else if ( len==BCF_VL_G ) { hts_expand(uint8_t,nsmpl,args->ntmp_arr2,args->tmp_arr2); uint8_t *haploid = args->tmp_arr2; int nret = bcf_get_format_char(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); nret /= nsmpl; for (i=0; itmp_arr1 + i*nret, *se = ss+nret; int nfields = 1; while ( *ss && ssn_allele ) { haploid[i] = 1; nfields = dst->n_allele; } else if ( nfields==lines[0]->n_allele*(lines[0]->n_allele+1)/2 ) { haploid[i] = 0; nfields = dst->n_allele*(dst->n_allele+1)/2; } else error("The field %s at %s:%"PRId64" neither diploid nor haploid?\n", tag,bcf_seqname(args->hdr,dst),(int64_t) dst->pos+1); kstring_t *tmp = &args->tmp_str[i]; kputc('.',tmp); for (j=1; jhdr,lines[i],tag,&args->tmp_arr1,&args->ntmp_arr1); if (nret<0) continue; /* format tag does not exist in this record, skip */ nret /= nsmpl; } for (k=0; ktmp_str[k]; char *src = (char*)args->tmp_arr1 + k*nret; if ( haploid[k] ) { for (j=0; jn_allele; j++) copy_string_field(src,j,nret, tmp, args->maps[i].map[j]); } else { int iori, jori, kori = 0; for (iori=0; iorin_allele; iori++) { int inew = args->maps[i].map[iori]; for (jori=0; jori<=iori; jori++) { int jnew = args->maps[i].map[jori]; int knew = bcf_alleles2gt(inew,jnew); copy_string_field(src,kori,nret,tmp,knew); kori++; } } } } } } kstring_t str; str.m = args->ntmp_arr2; str.l = 0; str.s = (char*) args->tmp_arr2; int max_len = 0; for (i=0; itmp_str[i].l ) max_len = args->tmp_str[i].l; for (i=0; itmp_str[i]; kputsn(tmp->s,tmp->l,&str); for (j=tmp->l; jntmp_arr2 = str.m; args->tmp_arr2 = (uint8_t*)str.s; bcf_update_format_char(args->out_hdr,dst,tag,str.s,str.l); } char **merge_alleles(char **a, int na, int *map, char **b, int *nb, int *mb); // see vcfmerge.c static void merge_biallelics_to_multiallelic(args_t *args, bcf1_t *dst, bcf1_t **lines, int nlines) { int i; for (i=0; irid = lines[0]->rid; dst->pos = lines[0]->pos; // take max for QUAL bcf_float_set_missing(dst->qual); for (i=0; iqual)) continue; if (bcf_float_is_missing(dst->qual) || dst->qualqual) dst->qual = lines[i]->qual; } bcf_update_id(args->out_hdr, dst, lines[0]->d.id); // Merge and set the alleles, create a mapping from source allele indexes to dst idxs hts_expand0(map_t,nlines,args->mmaps,args->maps); // a mapping for each line args->nals = args->maps[0].nals = lines[0]->n_allele; hts_expand(int,args->maps[0].nals,args->maps[0].mals,args->maps[0].map); hts_expand(char*,args->nals,args->mals,args->als); for (i=0; imaps[0].nals; i++) { args->maps[0].map[i] = i; args->als[i] = strdup(lines[0]->d.allele[i]); } for (i=1; id.id[0]!='.' || lines[i]->d.id[1]) bcf_add_id(args->out_hdr, dst, lines[i]->d.id); args->maps[i].nals = lines[i]->n_allele; hts_expand(int,args->maps[i].nals,args->maps[i].mals,args->maps[i].map); args->als = merge_alleles(lines[i]->d.allele, lines[i]->n_allele, args->maps[i].map, args->als, &args->nals, &args->mals); if ( !args->als ) error("Failed to merge alleles at %s:%"PRId64"\n", bcf_seqname(args->hdr,dst),(int64_t) dst->pos+1); } bcf_update_alleles(args->out_hdr, dst, (const char**)args->als, args->nals); for (i=0; inals; i++) { free(args->als[i]); args->als[i] = NULL; } if ( lines[0]->d.n_flt ) bcf_update_filter(args->out_hdr, dst, lines[0]->d.flt, lines[0]->d.n_flt); for (i=1; id.n_flt; j++) { // if strict_filter, set FILTER to PASS if any site PASS // otherwise accumulate FILTERs if (lines[i]->d.flt[j] == bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PASS")) { if (args->strict_filter) { bcf_update_filter(args->out_hdr, dst, lines[i]->d.flt, lines[i]->d.n_flt); break; } else continue; } bcf_add_filter(args->out_hdr, dst, lines[i]->d.flt[j]); } } // merge info for (i=0; in_info; i++) { bcf_info_t *info = &lines[0]->d.info[i]; int type = bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key); if ( type==BCF_HT_INT || type==BCF_HT_REAL ) merge_info_numeric(args, lines, nlines, info, dst); else if ( type==BCF_HT_FLAG ) merge_info_flag(args, lines, nlines, info, dst); else merge_info_string(args, lines, nlines, info, dst); } // merge format int gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); dst->n_sample = lines[0]->n_sample; for (i=0; in_fmt; i++) { bcf_fmt_t *fmt = &lines[0]->d.fmt[i]; int type = bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id); if ( fmt->id==gt_id ) merge_format_genotype(args, lines, nlines, fmt, dst); else if ( type==BCF_HT_INT || type==BCF_HT_REAL ) merge_format_numeric(args, lines, nlines, fmt, dst); else merge_format_string(args, lines, nlines, fmt, dst); } args->njoined++; } #define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } static void mrows_push(args_t *args, bcf1_t **line) { int i,m; if ( !args->nmrows ) args->mrows_first = 0; args->nmrows++; m = args->mmrows; hts_expand(bcf1_t*,args->nmrows,args->mmrows,args->mrows); for (i=m; immrows; i++) args->mrows[i] = bcf_init1(); SWAP(bcf1_t*, args->mrows[args->nmrows-1], *line); if ( args->mrows_collapse==COLLAPSE_ANY ) return; // move the line up the sorted list so that the same variant types end up together int cur_type = bcf_get_variant_types(args->mrows[args->nmrows-1]); i = args->mrows_first + args->nmrows - 1; while (i>0) { int prev_type = bcf_get_variant_types(args->mrows[i-1]); if ( prev_type <= cur_type ) break; bcf1_t *tmp = args->mrows[i-1]; args->mrows[i-1] = args->mrows[i]; args->mrows[i] = tmp; i--; } } static int mrows_can_flush(args_t *args, bcf1_t *line) { if ( !args->nmrows ) return 0; int ibeg = args->mrows_first; if ( args->mrows[ibeg]->rid != line->rid ) return 1; if ( args->mrows[ibeg]->pos != line->pos ) return 1; return 0; } static bcf1_t *mrows_flush(args_t *args) { if ( !args->nmrows ) return NULL; int ibeg = args->mrows_first; //fprintf(stderr,"flush: ibeg=%d n=%d\n",ibeg,args->nmrows); //int i; //for (i=ibeg; inmrows; i++) // fprintf(stderr,"\ti=%d type=%d %s %s\n",i,bcf_get_variant_types(args->mrows[i]),args->mrows[i]->d.allele[0],args->mrows[i]->d.allele[1]); if ( args->nmrows==1 ) { args->nmrows = 0; return args->mrows[ibeg]; } if ( args->mrows_collapse==COLLAPSE_ANY ) { // merge everything with anything bcf_clear(args->mrow_out); merge_biallelics_to_multiallelic(args, args->mrow_out, &args->mrows[ibeg], args->nmrows - ibeg); args->nmrows = 0; return args->mrow_out; } int j; int types[] = { VCF_SNP, VCF_MNP, VCF_INDEL, VCF_OTHER, -1 }; // merge everything within the same category if ( args->mrows_collapse==COLLAPSE_SNPS ) types[1] = -1; // merge SNPs only else if ( args->mrows_collapse==COLLAPSE_INDELS ) types[0] = VCF_INDEL, types[1] = -1; // merge indels only for (j=0; types[j]!=-1; j++) { int i, type = types[j]; // to keep the compiler happy for (i=ibeg; inmrows; i++) { type = bcf_get_variant_types(args->mrows[i]); if ( type!=types[j] && type!=VCF_REF ) break; } if ( i==ibeg+1 && type!=VCF_REF ) { // just one line of this type, no merging, but multiple lines of different type follow args->nmrows--; args->mrows_first++; return args->mrows[ibeg]; } if ( i>ibeg ) { // more than one line, merging is needed int nflush = i - ibeg; bcf_clear(args->mrow_out); merge_biallelics_to_multiallelic(args, args->mrow_out, &args->mrows[ibeg], nflush); args->nmrows -= nflush; args->mrows_first += nflush; return args->mrow_out; } } args->nmrows--; args->mrows_first++; return args->mrows[ibeg]; } static char *strdup_alt_svlen(args_t *args, bcf1_t *rec, int ial) { if ( rec->d.allele[ial][0]!='<' ) return strdup(rec->d.allele[ial]); int ntmp = args->ntmp_arr1 / sizeof(int32_t); int n = bcf_get_info_int32(args->hdr, rec, "SVLEN", &args->tmp_arr1, &ntmp); args->ntmp_arr1 = ntmp * sizeof(int32_t); int32_t *svlen = (int32_t *) args->tmp_arr1; if ( n<=0 ) return strdup(rec->d.allele[ial]); if ( n+1 != rec->n_allele ) { // there should be as many SVLEN numbers as there are ALT alleles static int warned = 0; if ( !warned ) { fprintf(stderr,"TODO: different number of ALT alleles and SVLEN fields %s:%"PRIhts_pos"\n",bcf_seqname(args->hdr,rec),rec->pos+1); warned = 1; } } kstring_t str = {0,0,0}; ksprintf(&str,"%s.%d",rec->d.allele[ial],svlen[ial-1]); return str.s; } static void cmpals_add(args_t *args, cmpals_t *ca, bcf1_t *rec) { ca->ncmpals++; hts_expand0(cmpals1_t, ca->ncmpals, ca->mcmpals, ca->cmpals); cmpals1_t *cmpals = ca->cmpals + ca->ncmpals - 1; free(cmpals->ref); cmpals->ref = strdup(rec->d.allele[0]); cmpals->n = rec->n_allele; if ( rec->n_allele==2 ) { free(cmpals->alt); cmpals->alt = strdup_alt_svlen(args,rec,1); } else { if ( cmpals->hash ) khash_str2int_destroy_free(cmpals->hash); cmpals->hash = khash_str2int_init(); int i; for (i=1; in_allele; i++) khash_str2int_inc(cmpals->hash, strdup(rec->d.allele[i])); } } static int cmpals_match(args_t *args, cmpals_t *ca, bcf1_t *rec) { int i, j; char *alt_svlen = rec->n_allele==2 ? strdup_alt_svlen(args,rec,1) : NULL; for (i=0; incmpals; i++) { cmpals1_t *cmpals = ca->cmpals + i; if ( rec->n_allele != cmpals->n ) continue; // NB. assuming both are normalized if ( strcasecmp(rec->d.allele[0], cmpals->ref) ) continue; // the most frequent case if ( rec->n_allele==2 ) { if ( strcasecmp(alt_svlen, cmpals->alt) ) continue; free(alt_svlen); return 1; } khash_t(str2int) *hash = (khash_t(str2int)*) cmpals->hash; for (j=1; jn_allele; j++) if ( !khash_str2int_has_key(hash, rec->d.allele[j]) ) break; if ( jn_allele ) continue; return 1; } free(alt_svlen); return 0; } static void cmpals_reset(cmpals_t *ca) { ca->ncmpals = 0; } static void cmpals_destroy(cmpals_t *ca) { int i; for (i=0; imcmpals; i++) { cmpals1_t *cmpals = ca->cmpals + i; free(cmpals->ref); free(cmpals->alt); if ( cmpals->hash ) khash_str2int_destroy_free(cmpals->hash); } free(ca->cmpals); } static void flush_buffer(args_t *args, htsFile *file, int n) { bcf1_t *line; int i, k; int prev_rid = -1, prev_pos = -1, prev_type = 0; for (i=0; irbuf); if ( args->mrows_op==MROWS_MERGE ) { if ( mrows_can_flush(args, args->lines[k]) ) { while ( (line=mrows_flush(args)) ) if ( bcf_write1(file, args->out_hdr, line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } mrows_push(args, &args->lines[k]); continue; } else if ( args->rmdup ) { int line_type = bcf_get_variant_types(args->lines[k]); if ( prev_rid>=0 && prev_rid==args->lines[k]->rid && prev_pos==args->lines[k]->pos ) { if ( args->rmdup & BCF_SR_PAIR_ANY ) continue; // rmdup by position only if ( args->rmdup & BCF_SR_PAIR_SNPS && line_type&(VCF_SNP|VCF_MNP) && prev_type&(VCF_SNP|VCF_MNP) ) continue; if ( args->rmdup & BCF_SR_PAIR_INDELS && line_type&(VCF_INDEL) && prev_type&(VCF_INDEL) ) continue; if ( args->rmdup & BCF_SR_PAIR_EXACT && cmpals_match(args, &args->cmpals_out, args->lines[k]) ) continue; } else { prev_rid = args->lines[k]->rid; prev_pos = args->lines[k]->pos; prev_type = 0; if ( args->rmdup & BCF_SR_PAIR_EXACT ) cmpals_reset(&args->cmpals_out); } prev_type |= line_type; if ( args->rmdup & BCF_SR_PAIR_EXACT ) cmpals_add(args,&args->cmpals_out, args->lines[k]); } if ( bcf_write1(file, args->out_hdr, args->lines[k])!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } if ( args->mrows_op==MROWS_MERGE && !args->rbuf.n ) { while ( (line=mrows_flush(args)) ) if ( bcf_write1(file, args->out_hdr, line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } } static void init_data(args_t *args) { args->hdr = args->files->readers[0].header; if ( args->keep_sum_ad ) { args->keep_sum_ad = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"AD"); if ( args->keep_sum_ad < 0 ) error("Error: --keep-sum-ad requested but the tag AD is not present\n"); } else args->keep_sum_ad = -1; args->out_hdr = args->hdr; if ( args->old_rec_tag ) bcf_hdr_printf(args->out_hdr,"##INFO=",args->old_rec_tag); rbuf_init(&args->rbuf, 100); args->lines = (bcf1_t**) calloc(args->rbuf.m, sizeof(bcf1_t*)); if ( args->ref_fname ) { args->fai = fai_load(args->ref_fname); if ( !args->fai ) error("Failed to load the fai index: %s\n", args->ref_fname); } if ( args->mrows_op==MROWS_MERGE ) { args->mrow_out = bcf_init1(); args->tmp_str = (kstring_t*) calloc(bcf_hdr_nsamples(args->hdr),sizeof(kstring_t)); args->diploid = (uint8_t*) malloc(bcf_hdr_nsamples(args->hdr)); } if ( args->atomize==SPLIT ) { args->abuf = abuf_init(args->hdr, SPLIT); abuf_set_opt(args->abuf, bcf_hdr_t*, BCF_HDR, args->out_hdr); if ( args->old_rec_tag ) { abuf_set_opt(args->abuf, const char*, INFO_TAG, args->old_rec_tag); if ( bcf_hdr_sync(args->out_hdr)!=0 ) error("bcf_hdr_sync failed\n"); } abuf_set_opt(args->abuf, int, STAR_ALLELE, args->use_star_allele); } if ( args->gff_fname ) { args->gff = gff_init(args->gff_fname); gff_set(args->gff,verbosity,args->gff_verbosity); gff_set(args->gff,strip_chr_names,1); gff_parse(args->gff); args->idx_tscript = gff_get(args->gff,idx_tscript); args->itr_tscript = regitr_init(NULL); } if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); args->filter_pass = 1; args->out_hdr = bcf_hdr_dup(args->out_hdr); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); if ( args->gff ) { gff_destroy(args->gff); regitr_destroy(args->itr_tscript); } cmpals_destroy(&args->cmpals_in); cmpals_destroy(&args->cmpals_out); int i; for (i=0; irbuf.m; i++) if ( args->lines[i] ) bcf_destroy1(args->lines[i]); free(args->lines); for (i=0; imtmp_lines; i++) if ( args->tmp_lines[i] ) bcf_destroy1(args->tmp_lines[i]); free(args->tmp_lines); for (i=0; immrows; i++) bcf_destroy1(args->mrows[i]); free(args->mrows); for (i=0; immaps; i++) free(args->maps[i].map); for (i=0; intmp_als; i++) free(args->tmp_als[i].s); for (i=0; intmp_sym; i++) free(args->tmp_sym[i].s); free(args->tmp_als); free(args->tmp_sym); free(args->tmp_kstr.s); if ( args->tmp_str ) { for (i=0; ihdr); i++) free(args->tmp_str[i].s); free(args->tmp_str); } free(args->maps); free(args->als); free(args->int32_arr); free(args->tmp_arr1); free(args->tmp_arr2); free(args->diploid); if ( args->abuf ) abuf_destroy(args->abuf); bcf_hdr_destroy(args->out_hdr); if ( args->mrow_out ) bcf_destroy1(args->mrow_out); if ( args->fai ) fai_destroy(args->fai); if ( args->mseq ) free(args->seq); } static void normalize_line(args_t *args, bcf1_t *line) { if ( args->fai ) { if ( args->filter_pass && (args->check_ref & CHECK_REF_FIX) ) fix_ref(args, line); if ( args->do_indels ) { int ret = args->filter_pass ? realign(args, line) : ERR_OK; // exclude broken VCF lines if ( ret==ERR_REF_MISMATCH && args->check_ref & CHECK_REF_SKIP ) { args->nskipped++; return; } if ( ret==ERR_DUP_ALLELE ) { if ( args->check_ref & CHECK_REF_FIX ) fix_dup_alt(args, line); else if ( args->check_ref==CHECK_REF_EXIT ) error("Duplicate alleles at %s:%"PRId64"; run with -cw to turn the error into warning or with -cs to fix.\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); else if ( args->check_ref & CHECK_REF_WARN ) fprintf(stderr,"ALT_DUP\t%s\t%"PRId64"\n", bcf_seqname(args->hdr,line),(int64_t) line->pos+1); } } } if ( args->filter_pass && args->atomize==SPLIT ) abuf_push(args->abuf,line); while (1) { if ( args->filter_pass && args->atomize==SPLIT ) { line = abuf_flush(args->abuf, 0); if ( !line ) break; } // insert into sorted buffer rbuf_expand0(&args->rbuf,bcf1_t*,args->rbuf.n+1,args->lines); int i,j; i = j = rbuf_append(&args->rbuf); if ( args->lines[i] ) bcf_destroy(args->lines[i]); args->lines[i] = bcf_dup(line); while ( rbuf_prev(&args->rbuf,&i) ) { if ( args->lines[i]->rid==args->lines[j]->rid ) { bcf_unpack(args->lines[i], BCF_UN_STR); bcf_unpack(args->lines[j], BCF_UN_STR); if ( args->cmp_func(&args->lines[i], &args->lines[j]) > 0) SWAP(bcf1_t*, args->lines[i], args->lines[j]); } j = i; } if ( !args->filter_pass || args->atomize!=SPLIT ) break; } } // return 0 on success, 1 when done static int split_and_normalize(args_t *args) { if ( !bcf_sr_next_line(args->files) ) return 1; bcf1_t *line = bcf_sr_get_line(args->files,0); args->ntotal++; if ( args->filter ) { args->filter_pass = filter_test(args->filter,line,NULL); if ( args->filter_logic==FLT_EXCLUDE ) args->filter_pass = args->filter_pass ? 0 : 1; if ( !args->filter_pass ) args->nfilter++; } if ( args->mrows_op!=MROWS_SPLIT || line->n_allele<=2 || !args->filter_pass ) { // normal operation, no splitting normalize_line(args, line); return 0; } // any restrictions on variant types to split? if ( args->mrows_collapse!=COLLAPSE_BOTH && args->mrows_collapse!=COLLAPSE_ANY ) { int type = args->mrows_collapse==COLLAPSE_SNPS ? VCF_SNP : VCF_INDEL; if ( !(bcf_get_variant_types(line) & type) ) { normalize_line(args, line); return 0; } } args->nsplit++; split_multiallelic_to_biallelics(args, line); int j; for (j=0; jntmp_lines; j++) normalize_line(args, args->tmp_lines[j]); return 0; } static void normalize_vcf(args_t *args) { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->n_threads ) hts_set_opt(args->out, HTS_OPT_THREAD_POOL, args->files->p); if (args->record_cmd_line) bcf_hdr_append_version(args->out_hdr, args->argc, args->argv, "bcftools_norm"); if ( bcf_hdr_write(args->out, args->out_hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out,args->out_hdr,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); while (1) { // buffer lines until a different position is reached int done = 0; while (1) { done = split_and_normalize(args); if ( done ) break; // no more lines available int i = args->rbuf.f; int j = rbuf_last(&args->rbuf); if ( args->lines[i]->rid != args->lines[j]->rid ) break; if ( args->lines[i]->pos != args->lines[j]->pos ) break; } if ( done ) break; // find out how many sites to flush int ifst = args->rbuf.f; int ilast = rbuf_last(&args->rbuf); int i, j = 0; for (i=-1; rbuf_next(&args->rbuf,&i); ) { if ( args->lines[ifst]->rid != args->lines[ilast]->rid ) { // there are two chromosomes in the buffer, count how many are on the first chromosome if ( args->lines[ifst]->rid != args->lines[i]->rid ) break; j++; continue; } // there is just one chromosome, flush only lines that are unlikely to change order on // realigning (the buf_win constant) if ( args->lines[ilast]->pos - args->lines[i]->pos < args->buf_win ) break; j++; } if ( j>0 ) flush_buffer(args, args->out, j); } flush_buffer(args, args->out, args->rbuf.n); if ( args->write_index ) { if ( bcf_idx_save(args->out)<0 ) { if ( hts_close(args->out)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); fprintf(stderr,"Lines total/split/joined/realigned/removed/skipped:\t%d/%d/%d/%d/%d/%d\n", args->ntotal,args->nsplit,args->njoined,args->nchanged,args->nskipped,args->nfilter); if ( args->check_ref & CHECK_REF_FIX ) fprintf(stderr,"REF/ALT total/modified/added: \t%d/%d/%d\n", args->nref.tot,args->nref.swap,args->nref.set); } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Left-align and normalize indels; check if REF alleles match the reference;\n"); fprintf(stderr, " split multiallelic sites into multiple rows; recover multiallelics from\n"); fprintf(stderr, " multiple rows.\n"); fprintf(stderr, "Usage: bcftools norm [options] \n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -a, --atomize Decompose complex variants (e.g. MNVs become consecutive SNVs)\n"); fprintf(stderr, " --atom-overlaps '*'|. Use the star allele (*) for overlapping alleles or set to missing (.) [*]\n"); fprintf(stderr, " -c, --check-ref e|w|x|s Check REF alleles and exit (e), warn (w), exclude (x), or set (s) bad sites [e]\n"); fprintf(stderr, " -D, --remove-duplicates Remove duplicate lines of the same type.\n"); fprintf(stderr, " -d, --rm-dup TYPE Remove duplicate snps|indels|both|all|exact\n"); fprintf(stderr, " -e, --exclude EXPR Do not normalize records for which the expression is true (see man page for details)\n"); fprintf(stderr, " -f, --fasta-ref FILE Reference sequence\n"); fprintf(stderr, " --force Try to proceed even if malformed tags are encountered. Experimental, use at your own risk\n"); fprintf(stderr, " -g, --gff-annot FILE Follow HGVS 3'rule and right-align variants in transcripts on the forward strand\n"); fprintf(stderr, " -i, --include EXPR Normalize only records for which the expression is true (see man page for details)\n"); fprintf(stderr, " --keep-sum TAG,.. Keep vector sum constant when splitting multiallelics (see github issue #360)\n"); fprintf(stderr, " -m, --multiallelics -|+TYPE Split multiallelics (-) or join biallelics (+), type: snps|indels|both|any [both]\n"); fprintf(stderr, " --multi-overlaps 0|. Fill in the reference (0) or missing (.) allele when splitting multiallelics [0]\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -N, --do-not-normalize Do not normalize indels (with -m or -c s)\n"); fprintf(stderr, " --old-rec-tag STR Annotate modified records with INFO/STR indicating the original variant\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --strict-filter When merging (-m+), merged site is PASS only if all sites being merged PASS\n"); fprintf(stderr, " -S, --sort METHOD Sort order: chr_pos,lex [chr_pos]\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " --threads INT Use multithreading with INT worker threads [0]\n"); fprintf(stderr, " -v, --verbose INT Verbosity level (0-2) of GFF parsing [1]\n"); fprintf(stderr, " -w, --site-win INT Buffer for sorting lines which changed position during realignment [1000]\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Examples:\n"); fprintf(stderr, " # normalize and left-align indels\n"); fprintf(stderr, " bcftools norm -f ref.fa in.vcf\n"); fprintf(stderr, "\n"); fprintf(stderr, " # split multi-allelic sites\n"); fprintf(stderr, " bcftools norm -m- in.vcf\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfnorm(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->files = bcf_sr_init(); args->output_fname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->aln_win = 100; args->buf_win = 1000; args->mrows_collapse = COLLAPSE_BOTH; args->do_indels = 1; args->ma_use_ref_allele = 1; args->clevel = -1; int region_is_file = 0; int targets_is_file = 0; args->use_star_allele = 1; args->gff_verbosity = 1; int regions_overlap = 1; int targets_overlap = 0; args->cmp_func = cmp_bcf_pos; static struct option loptions[] = { {"help",no_argument,NULL,'h'}, {"force",no_argument,NULL,7}, {"atomize",no_argument,NULL,'a'}, {"atom-overlaps",required_argument,NULL,11}, {"include",required_argument,NULL,'i'}, {"exclude",required_argument,NULL,'e'}, {"old-rec-tag",required_argument,NULL,12}, {"keep-sum",required_argument,NULL,10}, {"fasta-ref",required_argument,NULL,'f'}, {"sort",required_argument,NULL,'S'}, {"gff-annot",required_argument,NULL,'g'}, {"right-align",no_argument,NULL,15}, // undocumented, only for debugging {"do-not-normalize",no_argument,NULL,'N'}, {"multiallelics",required_argument,NULL,'m'}, {"multi-overlaps",required_argument,NULL,13}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,1}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,2}, {"site-win",required_argument,NULL,'w'}, {"remove-duplicates",no_argument,NULL,'D'}, {"rm-dup",required_argument,NULL,'d'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"check-ref",required_argument,NULL,'c'}, {"strict-filter",no_argument,NULL,'s'}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {"verbose",required_argument,NULL,'v'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "hr:R:f:w:Dd:o:O:c:m:t:T:sNag:W::v:S:i:e:",loptions,NULL)) >= 0) { switch (c) { case 10: // possibly generalize this also to INFO/AD and other tags if ( strcasecmp("ad",optarg) ) error("Error: only --keep-sum AD is currently supported. See https://github.com/samtools/bcftools/issues/360 for more.\n"); args->keep_sum_ad = 1; // this will be set to the header id or -1 in init_data break; case 'g': args->gff_fname = optarg; break; case 'v': args->gff_verbosity = atoi(optarg); if ( args->gff_verbosity<0 || args->gff_verbosity>2 ) error("Error: expected integer 0-2 with -v, --verbose\n"); break; case 'a': args->atomize = SPLIT; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'S': if ( !strcasecmp(optarg,"pos") ) args->cmp_func = cmp_bcf_pos; else if ( !strcasecmp(optarg,"lex") ) args->cmp_func = cmp_bcf_pos_ref_alt; else error("Error: the sort order --sort %s is not recognised\n",optarg); break; case 11 : if ( optarg[0]=='*' ) args->use_star_allele = 1; else if ( optarg[0]=='.' ) args->use_star_allele = 0; else error("Invalid argument to --atom-overlaps. Perhaps you wanted: \"--atom-overlaps '*'\"?\n"); break; case 12 : args->old_rec_tag = optarg; break; case 13 : if ( optarg[0]=='0' ) args->ma_use_ref_allele = 1; else if ( optarg[0]=='.' ) args->ma_use_ref_allele = 0; else error("Invalid argument to --multi-overlaps\n"); break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 15 : args->right_align = 1; break; case 'N': args->do_indels = 0; break; case 'd': if ( !strcmp("snps",optarg) ) args->rmdup = BCF_SR_PAIR_SNPS; else if ( !strcmp("indels",optarg) ) args->rmdup = BCF_SR_PAIR_INDELS; else if ( !strcmp("both",optarg) ) args->rmdup = BCF_SR_PAIR_BOTH; else if ( !strcmp("all",optarg) ) args->rmdup = BCF_SR_PAIR_ANY; else if ( !strcmp("any",optarg) ) args->rmdup = BCF_SR_PAIR_ANY; else if ( !strcmp("none",optarg) ) args->rmdup = BCF_SR_PAIR_EXACT; else if ( !strcmp("exact",optarg) ) args->rmdup = BCF_SR_PAIR_EXACT; else error("The argument to -d not recognised: %s\n", optarg); break; case 'm': if ( optarg[0]=='-' ) args->mrows_op = MROWS_SPLIT; else if ( optarg[0]=='+' ) args->mrows_op = MROWS_MERGE; else error("Expected '+' or '-' with -m\n"); if ( optarg[1]!=0 ) { if ( !strcmp("snps",optarg+1) ) args->mrows_collapse = COLLAPSE_SNPS; else if ( !strcmp("indels",optarg+1) ) args->mrows_collapse = COLLAPSE_INDELS; else if ( !strcmp("both",optarg+1) ) args->mrows_collapse = COLLAPSE_BOTH; else if ( !strcmp("any",optarg+1) ) args->mrows_collapse = COLLAPSE_ANY; else error("The argument to -m not recognised: %s\n", optarg); } break; case 'c': if ( strchr(optarg,'w') ) args->check_ref |= CHECK_REF_WARN; if ( strchr(optarg,'x') ) args->check_ref |= CHECK_REF_SKIP; if ( strchr(optarg,'s') ) args->check_ref |= CHECK_REF_FIX; if ( strchr(optarg,'e') ) args->check_ref = CHECK_REF_EXIT; // overrides the above break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } } if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'o': args->output_fname = optarg; break; case 'D': fprintf(stderr,"Warning: `-D` is functional but deprecated, replaced by and alias of `-d none`.\n"); args->rmdup = BCF_SR_PAIR_EXACT; break; case 's': args->strict_filter = 1; break; case 'f': args->ref_fname = optarg; break; case 'r': args->region = optarg; break; case 'R': args->region = optarg; region_is_file = 1; break; case 't': args->targets = optarg; break; case 'T': args->targets = optarg; targets_is_file = 1; break; case 'w': args->buf_win = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --site-win %s\n", optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 7 : args->force = 1; break; case 1 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 2 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(); } else fname = argv[optind]; if ( !args->ref_fname && !args->mrows_op && !args->rmdup && args->atomize==NONE ) error("Expected -a, -f, -m, -D or -d option\n"); if ( !args->check_ref && args->ref_fname ) args->check_ref = CHECK_REF_EXIT; if ( args->check_ref && !args->ref_fname ) error("Expected --fasta-ref with --check-ref\n"); if ( args->region ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->region,region_is_file)<0 ) error("Failed to read the regions: %s\n", args->region); } if ( args->targets ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets,targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets); } if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); init_data(args); normalize_vcf(args); destroy_data(args); bcf_sr_destroy(args->files); free(args); return 0; } bcftools-1.21/vcfplugin.c000066400000000000000000000676601467060157400154420ustar00rootroot00000000000000/* vcfplugin.c -- plugin modules for operating on VCF/BCF files. Copyright (C) 2013-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include "config.h" #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #ifdef _WIN32 #include #else #include #endif #include "bcftools.h" #include "vcmp.h" #include "filter.h" #ifdef ENABLE_BCF_PLUGINS typedef struct _plugin_t plugin_t; /** * Plugin API: * ---------- * const char *about(void) * - short description used by 'bcftools plugin -lv' * * const char *usage(void) * - longer description used by 'bcftools +name -h' * * int run(int argc, char **argv) * - if implemented, the control is immediately handed over to the plugin, * none of the init/process/destroy functions is called. Return 0 on * success or non-zero value on error. * * int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr) * - called once at startup, it initializes local variables. * Return 1 to suppress normal VCF/BCF header output, -1 on critical * errors, 0 otherwise. * * bcf1_t *process(bcf1_t *rec) * - called for each VCF record, return NULL for no output * * void destroy(void) * - called after all lines have been processed to clean up */ typedef void (*dl_version_f) (const char **, const char **); typedef int (*dl_run_f) (int, char **); typedef int (*dl_init_f) (int, char **, bcf_hdr_t *, bcf_hdr_t *); typedef char* (*dl_about_f) (void); typedef char* (*dl_usage_f) (void); typedef bcf1_t* (*dl_process_f) (bcf1_t *); typedef void (*dl_destroy_f) (void); struct _plugin_t { int argc; char *name, **argv; dl_version_f version; dl_run_f run; dl_init_f init; dl_about_f about; dl_usage_f usage; dl_process_f process; dl_destroy_f destroy; void *handle; }; struct _args_t; typedef struct _rm_tag_t { char *key; int hdr_id; void (*handler)(struct _args_t *, bcf1_t *, struct _rm_tag_t *); } rm_tag_t; typedef struct { char **cols; int ncols, mcols; char **als; int nals, mals; kstring_t line; int rid, start, end; } annot_line_t; typedef struct _annot_col_t { int icol, replace; char *hdr_key; int (*setter)(struct _args_t *, bcf1_t *, struct _annot_col_t *, void*); } annot_col_t; // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct _args_t { bcf_srs_t *files; bcf_hdr_t *hdr, *hdr_out; htsFile *out_fh; int output_type, n_threads, clevel; filter_t *filter; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE plugin_t plugin; int nplugin_paths; char **plugin_paths; char **argv, *output_fname, *regions_list, *targets_list; int argc, drop_header, verbose, record_cmd_line, plist_only; char *index_fn; int write_index; } args_t; char *msprintf(const char *fmt, ...); static void add_plugin_paths(args_t *args, const char *path) { while (1) { size_t len = strcspn(path, HTS_PATH_SEPARATOR_STR); if ( len == 0 ) { #ifdef PLUGINPATH add_plugin_paths(args, PLUGINPATH); #endif } else { char *dir = (char *) malloc(len + 1); strncpy(dir, path, len); dir[len] = '\0'; struct stat st; if ( stat(dir, &st) == 0 ) { args->plugin_paths = (char**) realloc(args->plugin_paths,sizeof(char*)*(args->nplugin_paths+1)); args->plugin_paths[args->nplugin_paths] = dir; args->nplugin_paths++; if ( args->verbose > 1 && strcmp(".",dir) ) fprintf(stderr, "plugin directory %s .. ok\n", dir); } else { if ( args->verbose > 1 ) fprintf(stderr, "plugin directory %s .. %s\n", dir, strerror(errno)); free(dir); } } path += len; if ( *path == HTS_PATH_SEPARATOR_CHAR ) path++; else break; } } static void init_plugin_paths(args_t *args) { if ( args->nplugin_paths!=-1 ) return; args->nplugin_paths = 0; args->plugin_paths = NULL; char *path = getenv("BCFTOOLS_PLUGINS"); add_plugin_paths(args, path ? path : ""); } static void *dlopen_plugin(args_t *args, const char *fname) { init_plugin_paths(args); void *handle; char *tmp; int is_absolute_path = 0; #ifdef _WIN32 // Windows accepts both forward slash (/) and backslash (\) as folder separator // and can have any path prefixed by the drive letter and a colon (:). if ( fname[0]=='/' || fname[0]=='\\') is_absolute_path = 1; else if ( fname[0] && fname[1]==':' && (fname[2]=='/' || fname[2]=='\\') ) is_absolute_path = 1; #else if ( fname[0]=='/' ) is_absolute_path = 1; #endif kstring_t err = {0,0,0}; if ( !is_absolute_path ) { int i; for (i=0; inplugin_paths; i++) { tmp = msprintf("%s/%s%s", args->plugin_paths[i], fname, PLUGIN_EXT); #ifdef _WIN32 handle = LoadLibraryA(tmp); #else handle = dlopen(tmp, RTLD_NOW); // valgrind complains about unfreed memory, not our problem though #endif if ( !handle ) #ifdef _WIN32 ksprintf(&err,"LoadLibraryA .. %lu\n", GetLastError()); #else ksprintf(&err,"%s:\n\tdlopen .. %s\n", tmp,dlerror()); #endif else if ( args->verbose > 1 ) fprintf(stderr,"%s:\n\tplugin open .. ok\n", tmp); free(tmp); if ( handle ) return handle; } } #ifdef _WIN32 handle = LoadLibraryA(fname); #else handle = dlopen(fname, RTLD_NOW); #endif if ( !handle ) #ifdef _WIN32 ksprintf(&err,"LoadLibraryA .. %lu\n", GetLastError()); #else ksprintf(&err,"%s:\n\tdlopen .. %s\n", fname,dlerror()); #endif else if ( args->verbose > 1 ) fprintf(stderr,"%s:\n\tplugin open .. ok\n", fname); if ( !handle && (!args->plist_only || args->verbose>1) ) fprintf(stderr,"%s",err.s); free(err.s); return handle; } static void print_plugin_usage_hint(const char *name) { if ( name ) fprintf(stderr, "\nThe bcftools plugin \"%s\" was not found or is not functional", name); else fprintf(stderr, "\nNo functional bcftools plugins were found"); if ( !getenv("BCFTOOLS_PLUGINS") ) { fprintf(stderr,". The environment variable BCFTOOLS_PLUGINS is not set"); #ifdef PLUGINPATH fprintf(stderr,"\nand no usable plugins were found in %s", PLUGINPATH); #endif fprintf(stderr,".\n\n"); } else { fprintf(stderr, " in\n\tBCFTOOLS_PLUGINS=\"%s\".\n\n" "- Is the plugin path correct?\n\n" "- Run \"bcftools plugin -l\" or \"bcftools plugin -lvv\" for a list of available plugins.\n" "\n", getenv("BCFTOOLS_PLUGINS") ); } } static int load_plugin(args_t *args, const char *fname, int exit_on_error, plugin_t *plugin) { plugin->name = strdup(fname); plugin->handle = dlopen_plugin(args, fname); if ( !plugin->handle ) { if ( exit_on_error ) { print_plugin_usage_hint(fname); error("Could not load \"%s\".\n\n", fname); } return -1; } #ifdef _WIN32 plugin->init = (dl_init_f) GetProcAddress(plugin->handle, "init"); if ( plugin->init && args->verbose > 1 ) fprintf(stderr,"\tinit .. ok\n"); plugin->run = (dl_run_f) GetProcAddress(plugin->handle, "run"); if ( plugin->run && args->verbose > 1 ) fprintf(stderr,"\trun .. ok\n"); if ( !plugin->init && !plugin->run ) { if ( exit_on_error ) error("Could not initialize %s, neither run or init found \n", plugin->name); else if ( args->verbose > 1 ) fprintf(stderr,"\tinit/run .. not found\n"); return -1; } plugin->version = (dl_version_f) GetProcAddress(plugin->handle, "version"); if ( !plugin->version ) { if ( exit_on_error ) error("Could not initialize %s: version string not found\n", plugin->name); else if ( args->verbose > 1 ) fprintf(stderr,"\tversion .. not found\n"); return -1; } plugin->about = (dl_about_f) GetProcAddress(plugin->handle, "about"); if ( !plugin->about ) { if ( exit_on_error ) error("Could not initialize %s: about string not found\n", plugin->name); return -1; } plugin->usage = (dl_about_f) GetProcAddress(plugin->handle, "usage"); if ( !plugin->usage ) plugin->usage = plugin->about; if ( plugin->run ) return 0; plugin->process = (dl_process_f) GetProcAddress(plugin->handle, "process"); if ( !plugin->process ) { if ( exit_on_error ) error("Could not initialize %s: process method not found\n", plugin->name); return -1; } plugin->destroy = (dl_destroy_f) GetProcAddress(plugin->handle, "destroy"); if ( !plugin->destroy ) { if ( exit_on_error ) error("Could not initialize %s: destroy method not found\n", plugin->name); return -1; } #else dlerror(); plugin->init = (dl_init_f) dlsym(plugin->handle, "init"); char *ret = dlerror(); if ( ret ) plugin->init = NULL; else if ( args->verbose > 1 ) fprintf(stderr,"\tinit .. ok\n"); plugin->run = (dl_run_f) dlsym(plugin->handle, "run"); ret = dlerror(); if ( ret ) plugin->run = NULL; else if ( args->verbose > 1 ) fprintf(stderr,"\trun .. ok\n"); if ( !plugin->init && !plugin->run ) { if ( exit_on_error ) error("Could not initialize %s, neither run or init found \n", plugin->name); else if ( args->verbose > 1 ) fprintf(stderr,"\tinit/run .. not found\n"); return -1; } plugin->version = (dl_version_f) dlsym(plugin->handle, "version"); ret = dlerror(); if ( ret ) { if ( exit_on_error ) error("Could not initialize %s, version string not found\n", plugin->name); else if ( args->verbose > 1 ) fprintf(stderr,"\tversion .. not found\n"); return -1; } plugin->about = (dl_about_f) dlsym(plugin->handle, "about"); ret = dlerror(); if ( ret ) { if ( exit_on_error ) error("Could not initialize %s: %s\n", plugin->name, ret); return -1; } plugin->usage = (dl_about_f) dlsym(plugin->handle, "usage"); ret = dlerror(); if ( ret ) plugin->usage = plugin->about; if ( plugin->run ) return 0; plugin->process = (dl_process_f) dlsym(plugin->handle, "process"); ret = dlerror(); if ( ret ) { if ( exit_on_error ) error("Could not initialize %s: %s\n", plugin->name, ret); return -1; } plugin->destroy = (dl_destroy_f) dlsym(plugin->handle, "destroy"); ret = dlerror(); if ( ret ) { if ( exit_on_error ) error("Could not initialize %s: %s\n", plugin->name, ret); return -1; } #endif return 0; } static void check_version(args_t *args) { static int warned_bcftools = 0, warned_htslib = 0; const char *bver, *hver; args->plugin.version(&bver, &hver); if ( strcmp(bver,bcftools_version()) && !warned_bcftools ) { fprintf(stderr,"WARNING: bcftools version mismatch .. bcftools at %s, the plugin \"%s\" at %s\n", bcftools_version(),args->plugin.name,bver); warned_bcftools = 1; } if ( strcmp(hver,hts_version()) && !warned_htslib ) { fprintf(stderr,"WARNING: htslib version mismatch .. bcftools at %s, the plugin \"%s\" at %s\n", hts_version(),args->plugin.name,hver); warned_htslib = 1; } } static void init_plugin(args_t *args) { int ret = args->plugin.init(args->plugin.argc,args->plugin.argv,args->hdr,args->hdr_out); if ( ret<0 ) error("The plugin exited with an error.\n"); check_version(args); args->drop_header += ret; } static int cmp_plugin_name(const void *p1, const void *p2) { plugin_t *a = (plugin_t*) p1; plugin_t *b = (plugin_t*) p2; return strcmp(a->name,b->name); } // If args=NULL then returns the number of plugins available. Otherwise prints the // plugins on stdout and returns 0 on success. static int list_plugins(args_t *args) { plugin_t *plugins = NULL; int nplugins = 0, mplugins = 0; int count_only = 0; args_t _args; if ( !args ) { memset(&_args,0,sizeof(_args)); args = &_args; args->nplugin_paths = -1; count_only = 1; } init_plugin_paths(args); kstring_t str = {0,0,0}; int plugin_ext_len = strlen(PLUGIN_EXT); int i; for (i=0; inplugin_paths; i++) { DIR *dp = opendir(args->plugin_paths[i]); if ( dp==NULL ) continue; struct dirent *ep; while ( (ep=readdir(dp)) ) { int len = strlen(ep->d_name); if ( strcasecmp(PLUGIN_EXT,ep->d_name+len-plugin_ext_len) ) continue; str.l = 0; ksprintf(&str,"%s/%s", args->plugin_paths[i],ep->d_name); hts_expand(plugin_t, nplugins+1, mplugins, plugins); if ( load_plugin(args, str.s, 0, &plugins[nplugins]) < 0 ) continue; nplugins++; str.l = 0; kputs(ep->d_name, &str); int l = str.l - 1; while ( l>=0 && str.s[l]!='.' ) l--; if ( l>=0 ) str.s[l] = 0; free(plugins[nplugins-1].name); plugins[nplugins-1].name = strdup(str.s); // use a short name } closedir(dp); } if ( count_only ) { free(str.s); return nplugins; } if ( nplugins ) { qsort(plugins, nplugins, sizeof(plugins[0]), cmp_plugin_name); for (i=0; iverbose ) printf("\n-- %s --\n%s", plugins[i].name, plugins[i].about()); else printf("%s\n", plugins[i].name); } if ( args->verbose ) printf("\n"); } else print_plugin_usage_hint(NULL); free(str.s); return nplugins ? 0 : 1; } int count_plugins(void) { return list_plugins(NULL); } static void init_data(args_t *args) { args->hdr = args->files->readers[0].header; args->hdr_out = bcf_hdr_dup(args->hdr); init_plugin(args); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); if (args->record_cmd_line) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_plugin"); if ( !args->drop_header ) { char wmode[8]; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); args->out_fh = hts_open(args->output_fname ? args->output_fname : "-", wmode); if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); if ( bcf_hdr_write(args->out_fh, args->hdr_out)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); if ( init_index2(args->out_fh,args->hdr_out,args->output_fname, &args->index_fn, args->write_index)<0 ) error("Error: failed to initialise index for %s\n",args->output_fname); } } static void destroy_data(args_t *args) { free(args->plugin.name); if ( args->plugin.destroy ) args->plugin.destroy(); #ifdef _WIN32 FreeLibrary(args->plugin.handle); #else dlclose(args->plugin.handle); #endif if ( args->hdr_out ) bcf_hdr_destroy(args->hdr_out); if ( args->nplugin_paths>0 ) { int i; for (i=0; inplugin_paths; i++) free(args->plugin_paths[i]); free(args->plugin_paths); } if ( args->filter ) filter_destroy(args->filter); if (args->out_fh ) { if ( args->write_index ) { if ( bcf_idx_save(args->out_fh)<0 ) { if ( hts_close(args->out_fh)!=0 ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out_fh)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->output_fname); } } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Run user defined plugin\n"); fprintf(stderr, "Usage: bcftools plugin [OPTIONS] [-- PLUGIN_OPTIONS]\n"); fprintf(stderr, " bcftools +name [OPTIONS] [-- PLUGIN_OPTIONS]\n"); fprintf(stderr, "\n"); fprintf(stderr, "VCF input options:\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true\n"); fprintf(stderr, " -i, --include EXPR Select sites for which the expression is true\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, "VCF output options:\n"); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " --threads INTT Use multithreading with worker threads [0]\n"); fprintf(stderr, "Plugin options:\n"); fprintf(stderr, " -h, --help List plugin's options\n"); fprintf(stderr, " -l, --list-plugins List available plugins. See BCFTOOLS_PLUGINS environment variable and man page for details\n"); fprintf(stderr, " -v, --verbose Print verbose information, -vv increases verbosity\n"); fprintf(stderr, " -V, --version Print version string and exit\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); exit(1); } static int is_verbose(int argc, char *argv[]) { int c, verbose = 0, opterr_ori = opterr; static struct option loptions[] = { {"verbose",no_argument,NULL,'v'}, {NULL,0,NULL,0} }; opterr = 0; while ((c = getopt_long(argc, argv, "-v",loptions,NULL)) >= 0) { switch (c) { case 'v': verbose++; break; case 1: default: break; } } opterr = opterr_ori; optind = 0; return verbose; } int main_plugin(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->output_fname = "-"; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->nplugin_paths = -1; args->clevel = -1; int regions_is_file = 0, targets_is_file = 0, usage_only = 0, version_only = 0; int regions_overlap = 1; int targets_overlap = 0; if ( argc==1 ) usage(args); char *plugin_name = NULL; if ( argv[1][0]!='-' ) { args->verbose = is_verbose(argc, argv); plugin_name = argv[1]; argc--; argv++; load_plugin(args, plugin_name, 1, &args->plugin); if ( args->plugin.run ) { check_version(args); int ret = args->plugin.run(argc, argv); destroy_data(args); free(args); return ret; } } static struct option loptions[] = { {"version",no_argument,NULL,'V'}, {"verbose",no_argument,NULL,'v'}, {"help",no_argument,NULL,'h'}, {"list-plugins",no_argument,NULL,'l'}, {"output",required_argument,NULL,'o'}, {"output-type",required_argument,NULL,'O'}, {"threads",required_argument,NULL,9}, {"include",required_argument,NULL,'i'}, {"exclude",required_argument,NULL,'e'}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,1}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,2}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "h?o:O:r:R:t:T:li:e:vVW::",loptions,NULL)) >= 0) { switch (c) { case 'V': version_only = 1; break; case 'v': args->verbose++; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'l': args->plist_only = 1; break; case 1 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 2 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case '?': case 'h': usage_only = 1; break; default: error("Unknown argument: %s\n", optarg); } } if ( args->plist_only ) return list_plugins(args); if ( !plugin_name ) usage(args); if ( version_only ) { const char *bver, *hver; args->plugin.version(&bver, &hver); printf("bcftools %s using htslib %s\n", bcftools_version(), hts_version()); printf("plugin at %s using htslib %s\n\n", bver, hver); return 0; } if ( usage_only ) { if ( args->plugin.usage ) fprintf(stderr,"%s",args->plugin.usage()); else fprintf(stderr,"Usage: bcftools +%s [General Options] -- [Plugin Options]\n",plugin_name); return 0; } char *fname = NULL; if ( optind>=argc || (argv[optind][0]=='-' && argv[optind][1]) ) { args->plugin.argc = argc - optind + 1; args->plugin.argv = argv + optind - 1; if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else if ( optind>=argc ) usage(args); else { optind = 1; init_plugin(args); } } else { fname = argv[optind]; args->plugin.argc = argc - optind; args->plugin.argv = argv + optind; } optind = 0; args->files = bcf_sr_init(); if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); args->files->collapse |= COLLAPSE_SOME; } if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); init_data(args); while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) continue; } line = args->plugin.process(line); if ( line ) { if ( line->errcode ) error("[E::main_plugin] Unchecked error (%d), exiting\n",line->errcode); if ( bcf_write1(args->out_fh, args->hdr_out, line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->output_fname); } } destroy_data(args); bcf_sr_destroy(args->files); free(args); return 0; } #else /* ENABLE_BCF_PLUGINS */ int main_plugin(int argc, char *argv[]) { fprintf(stderr, "bcftools plugins are disabled. To use them, you will need to rebuild\n" "bcftools from the source distribution with plugins enabled.\n"); return 1; } #endif /* ENABLE_BCF_PLUGINS */ bcftools-1.21/vcfquery.c000066400000000000000000000457471467060157400153130ustar00rootroot00000000000000/* vcfquery.c -- Extracts fields from VCF/BCF file. Copyright (C) 2013-2023 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "convert.h" #include "smpl_ilist.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 typedef struct { filter_t *filter; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE uint8_t *smpl_pass; convert_t *convert; bcf_srs_t *files; bcf_hdr_t *header; int sample_is_file; char **argv, *format_str, *sample_list, *targets_list, *regions_list, *vcf_list, *fn_out; char *print_filtered; int argc, list_columns, print_header, allow_undef_tags, force_samples, force_newline; FILE *out; } args_t; static void destroy_list(char **list, int n) { int i; for (i=0; iheader = args->files->readers[0].header; int i, nsamples = 0, *samples = NULL; if ( args->sample_list && strcmp("-",args->sample_list) ) { for (i=0; ifiles->nreaders; i++) { // This tells htslib to subset samples directly when reading. Also the header is modified to // include only the requested samples int ret = bcf_hdr_set_samples(args->files->readers[i].header,args->sample_list,args->sample_is_file); if ( ret<0 ) error("Error parsing the sample list\n"); else if ( ret>0 && !args->force_samples ) error("Error: sample #%d not found in the header, user --force-samples to proceed anyway\n", ret); } int flags = SMPL_REORDER; smpl_ilist_t *ilist = smpl_ilist_init(args->files->readers[0].header, args->sample_list, args->sample_is_file, flags); nsamples = ilist->n; samples = (int*) malloc(sizeof(int)*nsamples); for (i=0; in; i++) samples[i] = ilist->idx[i]; smpl_ilist_destroy(ilist); } args->convert = convert_init(args->header, samples, nsamples, args->format_str); if ( args->force_newline ) convert_set_option(args->convert, force_newline, 1); convert_set_option(args->convert, subset_samples, &args->smpl_pass); if ( args->allow_undef_tags ) convert_set_option(args->convert, allow_undef_tags, 1); if ( args->print_header>1 ) convert_set_option(args->convert, no_hdr_indices, 1); free(samples); int max_unpack = convert_max_unpack(args->convert); if ( args->filter_str ) { args->filter = filter_init(args->header, args->filter_str); max_unpack |= filter_max_unpack(args->filter); } args->files->max_unpack = max_unpack; if ( !args->filter || args->print_filtered || !(filter_max_unpack(args->filter) & BCF_UN_FMT) ) convert_set_option(args->convert, header_samples, 1); if ( args->print_filtered ) convert_set_option(args->convert, print_filtered, args->print_filtered); } static void destroy_data(args_t *args) { convert_destroy(args->convert); if ( args->filter ) filter_destroy(args->filter); } static void query_vcf(args_t *args) { kstring_t str = {0,0,0}; if ( args->print_header ) { convert_header(args->convert,&str); if ( fwrite(str.s, str.l, 1, args->out)!=1 ) error("[%s] Error: cannot write to %s\n", __func__,args->fn_out?args->fn_out:"standard output"); } int i,max_convert_unpack = convert_max_unpack(args->convert); int max_filter_unpack = args->filter ? filter_max_unpack(args->filter) : 0; while ( bcf_sr_next_line(args->files) ) { if ( !bcf_sr_has_line(args->files,0) ) continue; bcf1_t *line = args->files->readers[0].buffer[0]; bcf_unpack(line, args->files->max_unpack); if ( args->filter ) { int pass = filter_test(args->filter, line, (const uint8_t**) &args->smpl_pass); if ( args->filter_logic & FLT_EXCLUDE ) { // This code addresses this problem: // -i can include a site but exclude a sample // -e exclude a site but include a sample if ( pass ) { if ( !args->smpl_pass ) continue; if ( !(max_convert_unpack & BCF_UN_FMT) && !(max_filter_unpack & BCF_UN_FMT) ) continue; pass = 0; for (i=0; in_sample; i++) { if ( args->smpl_pass[i] ) args->smpl_pass[i] = 0; else { args->smpl_pass[i] = 1; pass = 1; } } if ( !pass ) continue; } else if ( args->smpl_pass ) for (i=0; in_sample; i++) args->smpl_pass[i] = 1; } else if ( !pass ) continue; } str.l = 0; convert_line(args->convert, line, &str); if ( str.l && fwrite(str.s, str.l, 1, args->out)!=1 ) error("[%s] Error: cannot write to %s\n", __func__,args->fn_out?args->fn_out:"standard output"); } if ( str.m ) free(str.s); } static void list_columns(args_t *args) { int negate = 0; int i; bcf_sr_t *reader = &args->files->readers[0]; void *has_sample = NULL; if ( args->sample_list ) { if ( args->sample_list[0]=='^' ) negate = 1; has_sample = khash_str2int_init(); int i, nsmpl; char **smpl = hts_readlist(negate ? args->sample_list+1 : args->sample_list, args->sample_is_file, &nsmpl); if ( !smpl ) error("Error: failed to read %s\n", negate ? args->sample_list+1 : args->sample_list); for (i=0; iheader,BCF_DT_SAMPLE,smpl[i])<0 && !args->force_samples ) error("Error: sample #%d not found in the header, user --force-samples to proceed anyway\n", i+1); khash_str2int_inc(has_sample, smpl[i]); } free(smpl); } for (i=0; iheader); i++) { int skip = 0; if ( negate ) { if ( khash_str2int_has_key(has_sample, reader->header->samples[i]) ) skip = 1; } else if ( has_sample && !khash_str2int_has_key(has_sample, reader->header->samples[i]) ) skip = 1; if ( skip ) continue; printf("%s\n", reader->header->samples[i]); } if ( has_sample ) khash_str2int_destroy_free(has_sample); } static char **copy_header(bcf_hdr_t *hdr, char **src, int nsrc) { char **dst = (char**) malloc(sizeof(char*)*nsrc); int i; for (i=0; i [ [...]]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " --force-samples Only warn about unknown subset samples\n"); fprintf(stderr, " -F, --print-filtered STR Output STR for samples failing the -i/-e filtering expression\n"); fprintf(stderr, " -f, --format STRING See man page for details\n"); fprintf(stderr, " -H, --print-header Print header, -HH to omit column indices\n"); fprintf(stderr, " -i, --include EXPR Select sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -l, --list-samples Print the list of samples and exit\n"); fprintf(stderr, " -N, --disable-automatic-newline Disable automatic addition of newline character when not present\n"); fprintf(stderr, " -o, --output FILE Output file name [stdout]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples LIST List of samples to include\n"); fprintf(stderr, " -S, --samples-file FILE File of samples to include\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " -u, --allow-undef-tags Print \".\" for undefined tags\n"); fprintf(stderr, " -v, --vcf-list FILE Process multiple VCFs listed in the file\n"); fprintf(stderr, "\n"); fprintf(stderr, "Examples:\n"); fprintf(stderr, "\tbcftools query -f '%%CHROM\\t%%POS\\t%%REF\\t%%ALT[\\t%%SAMPLE=%%GT]\\n' file.vcf.gz\n"); fprintf(stderr, "\t# For more examples see http://samtools.github.io/bcftools/bcftools.html#query\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfquery(int argc, char *argv[]) { int c, collapse = 0; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->force_newline = 1; int regions_is_file = 0, targets_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; static struct option loptions[] = { {"help",0,0,'h'}, {"list-samples",0,0,'l'}, {"disable-automatic-newline",required_argument,NULL,'N'}, {"include",1,0,'i'}, {"exclude",1,0,'e'}, {"print-filtered",1,0,'F'}, {"format",1,0,'f'}, {"force-samples",0,0,3}, {"output-file",1,0,'o'}, {"output",1,0,'o'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,1}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,2}, {"annots",1,0,'a'}, {"samples",1,0,'s'}, {"samples-file",1,0,'S'}, {"print-header",0,0,'H'}, {"collapse",1,0,'c'}, {"vcf-list",1,0,'v'}, {"allow-undef-tags",0,0,'u'}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "hlr:R:F:f:a:s:S:Ht:T:c:v:i:e:o:uN",loptions,NULL)) >= 0) { switch (c) { case 'o': args->fn_out = optarg; break; case 'F': args->print_filtered = optarg; break; case 'f': args->format_str = strdup(optarg); break; case 'N': args->force_newline = 0; break; case 'H': args->print_header++; break; case 'v': args->vcf_list = optarg; break; case 'c': error("The --collapse option is obsolete, pipe through `bcftools norm -c` instead.\n"); break; case 'a': { kstring_t str = {0,0,0}; kputs("%CHROM\t%POS\t%MASK\t%REF\t%ALT\t%", &str); char *p = optarg; while ( *p ) { if ( *p==',' ) kputs("\t%", &str); else kputc(*p, &str); p++; } kputc('\n', &str); args->format_str = str.s; break; } case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'l': args->list_columns = 1; break; case 'u': args->allow_undef_tags = 1; break; case 's': args->sample_list = optarg; break; case 'S': args->sample_list = optarg; args->sample_is_file = 1; break; case 1 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 2 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 3 : args->force_samples = 1; break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; } else fname = argv[optind]; if ( args->list_columns ) { if ( !fname ) error("Missing the VCF file name\n"); args->files = bcf_sr_init(); if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); list_columns(args); bcf_sr_destroy(args->files); free(args); return 0; } if ( !args->format_str ) { if ( argc==1 && !fname ) usage(); error("Error: Missing the --format option\n"); } args->out = args->fn_out ? fopen(args->fn_out, "w") : stdout; if ( !args->out ) error("%s: %s\n", args->fn_out,strerror(errno)); if ( !args->vcf_list ) { if ( !fname ) usage(); args->files = bcf_sr_init(); if ( optind+1 < argc ) args->files->require_index = 1; if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } while ( fname ) { if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); fname = ++optind < argc ? argv[optind] : NULL; } init_data(args); query_vcf(args); free(args->format_str); destroy_data(args); bcf_sr_destroy(args->files); if ( fclose(args->out)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fn_out); free(args); return 0; } // multiple VCFs int i, k, nfiles, prev_nsamples = 0; char **fnames, **prev_samples = NULL; fnames = hts_readlist(args->vcf_list, 1, &nfiles); if ( !fnames ) error("Error: failed to read %s\n", args->vcf_list); if ( !nfiles ) error("No files in %s?\n", args->vcf_list); for (i=0; ifiles = bcf_sr_init(); args->files->collapse = collapse; if ( args->regions_list && bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); if ( optind < argc ) args->files->require_index = 1; if ( args->targets_list ) { if ( bcf_sr_set_targets(args->files, args->targets_list,targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( !bcf_sr_add_reader(args->files, fnames[i]) ) error("Failed to open %s: %s\n", fnames[i],bcf_sr_strerror(args->files->errnum)); for (k=optind; kfiles, argv[k]) ) error("Failed to open %s: %s\n", argv[k],bcf_sr_strerror(args->files->errnum)); init_data(args); if ( i==0 ) { prev_samples = copy_header(args->header, args->files->readers[0].header->samples, bcf_hdr_nsamples(args->files->readers[0].header)); prev_nsamples = bcf_hdr_nsamples(args->files->readers[0].header); } else { args->print_header = 0; if ( compare_header(args->header, args->files->readers[0].header->samples, bcf_hdr_nsamples(args->files->readers[0].header), prev_samples, prev_nsamples) ) error("Different samples in %s and %s\n", fnames[i-1],fnames[i]); } query_vcf(args); destroy_data(args); bcf_sr_destroy(args->files); } if ( fclose(args->out)!=0 ) error("[%s] Error: close failed .. %s\n", __func__,args->fn_out);; destroy_list(fnames, nfiles); destroy_list(prev_samples, prev_nsamples); free(args->format_str); free(args); return 0; } bcftools-1.21/vcfroh.c000066400000000000000000001436721467060157400147320ustar00rootroot00000000000000/* vcfroh.c -- HMM model for detecting runs of autozygosity. Copyright (C) 2013-2022 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "HMM.h" #include "smpl_ilist.h" #include "filter.h" #define STATE_HW 0 // normal state, follows Hardy-Weinberg allele frequencies #define STATE_AZ 1 // autozygous state #define OUTPUT_ST (1<<1) #define OUTPUT_RG (1<<2) #define OUTPUT_GZ (1<<3) // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 /** Genetic map */ typedef struct { int pos; double rate; } genmap_t; /** HMM data for each sample */ typedef struct { double *eprob; // emission probs [2*nsites,msites] uint32_t *sites; // positions [nsites,msites] int nsites, msites; int igenmap; // current position in genmap int nused; // some stats to detect if things didn't go wrong int nrid, *rid, *rid_off; // for viterbi training, keep all chromosomes void *snapshot; // hmm snapshot struct { uint32_t beg,end,nqual; double qual; int rid, state; } rg; } smpl_t; typedef struct _args_t { bcf_srs_t *files; bcf_hdr_t *hdr; double t2AZ, t2HW; // P(AZ|HW) and P(HW|AZ) parameters double unseen_PL, dflt_AF; char *genmap_fname; genmap_t *genmap; int ngenmap, mgenmap, igenmap; double rec_rate; // constant recombination rate if > 0 hmm_t *hmm; double baum_welch_th; int nrids, *rids, *rid_offs; // multiple chroms with vi_training int nbuf_max, nbuf_olap; float *AFs; int32_t *itmp; int mAFs, nitmp, mitmp, pl_hdr_id, gt_hdr_id; double pl2p[256], *pdg; int32_t skip_rid, prev_rid, prev_pos; int ntot; // some stats to detect if things didn't go wrong int nno_af; // number of sites rejected because AF could not be determined int nfiltered; // .. because of filters int nno_alt, nmultiallelic, ndup; smpl_t *smpl; // HMM data for each sample smpl_ilist_t *af_smpl; // list of samples to estimate AF from (--estimate-AF) smpl_ilist_t *roh_smpl; // list of samples to analyze (--samples, --samples-file) char *estimate_AF; // list of samples for AF estimate and query sample int af_from_PL; // estimate AF from FMT/PL rather than FMT/GT char **argv, *targets_list, *regions_list, *af_fname, *af_tag, *samples, *buffer_size, *output_fname; int argc, fake_PLs, snps_only, vi_training, samples_is_file, output_type, skip_homref, n_threads; int include_noalt_sites; BGZF *out; kstring_t str; int filter_logic; filter_t *filter; char *filter_str; } args_t; void set_tprob_genmap(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob); void set_tprob_rrate(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob); void *smalloc(size_t size) { void *mem = malloc(size); if ( !mem ) error("malloc: Could not allocate %d bytes\n", (int)size); return mem; } static inline int max255(int i) { return i < 256 ? i : 255; } static void init_data(args_t *args) { int i; args->prev_rid = args->skip_rid = -1; args->hdr = args->files->readers[0].header; if ( !bcf_hdr_nsamples(args->hdr) ) error("No samples in the VCF?\n"); if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); if ( !args->fake_PLs ) { args->pl_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL"); if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->pl_hdr_id) ) error("Error: The FORMAT/PL tag not found in the header, consider running with -G\n"); if ( bcf_hdr_id2type(args->hdr,BCF_HL_FMT,args->pl_hdr_id)!=BCF_HT_INT ) error("Error: The FORMAT/PL tag not defined as Integer in the header\n"); } if ( args->estimate_AF ) { if ( !strncmp("GT,",args->estimate_AF,3) ) args->estimate_AF += 3; else if ( !strncmp("PL,",args->estimate_AF,3) ) { args->estimate_AF += 3; args->af_from_PL = 1; } if ( strcmp("-",args->estimate_AF) ) args->af_smpl = smpl_ilist_init(args->hdr, args->estimate_AF, 1, SMPL_NONE|SMPL_VERBOSE); } if ( args->estimate_AF || args->fake_PLs ) { if ( args->af_from_PL ) { args->pl_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL"); if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->pl_hdr_id) ) error("Error: The FORMAT/PL tag not found in the header\n"); } else { args->gt_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT"); if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->gt_hdr_id) ) error("Error: The FORMAT/GT tag not found in the header\n"); } } if ( args->fake_PLs ) { args->gt_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT"); if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->gt_hdr_id) ) error("Error: The FORMAT/GT tag not found in the header\n"); } args->roh_smpl = smpl_ilist_init(args->hdr, args->samples, args->samples_is_file, SMPL_NONE|SMPL_VERBOSE); if ( args->samples ) { // we may be able to subset to a few samples, for a text VCF this can be a major speedup if ( (bcf_sr_get_reader(args->files,0))->file->format.format==vcf ) { kstring_t str = {0,0,0}; smpl_ilist_t *tmp = args->roh_smpl, *rmme = NULL; if ( args->af_smpl ) { for (i=0; iroh_smpl->n; i++) { if ( str.l ) kputc(',', &str); kputs(args->hdr->samples[args->roh_smpl->idx[i]], &str); } for (i=0; iaf_smpl->n; i++) { kputc(',', &str); kputs(args->hdr->samples[args->af_smpl->idx[i]], &str); } rmme = tmp = smpl_ilist_init(args->hdr, str.s, 0, SMPL_NONE); } if ( tmp->n < bcf_hdr_nsamples(args->hdr) ) { str.l = 0; for (i=0; in; i++) { if ( str.l ) kputc(',', &str); kputs(args->hdr->samples[tmp->idx[i]], &str); } int ret = bcf_hdr_set_samples(args->hdr, str.s, 0); if ( ret<0 ) error("Error parsing the list of samples: %s\n", str.s); else if ( ret>0 ) error("The %d-th sample not found in the VCF: %s\n", ret,str.s); // update sample ids smpl_ilist_destroy(args->roh_smpl); args->roh_smpl = smpl_ilist_init(args->hdr, args->samples, args->samples_is_file, SMPL_NONE); if ( args->af_smpl ) { smpl_ilist_destroy(args->af_smpl); args->af_smpl = smpl_ilist_init(args->hdr, args->estimate_AF, 1, SMPL_NONE); } } free(str.s); if ( rmme ) smpl_ilist_destroy(rmme); } } // check whether all samples are in this list. If so, the lookup will not be needed if ( args->af_smpl && args->af_smpl->n == bcf_hdr_nsamples(args->hdr) ) { // all samples are in this list smpl_ilist_destroy(args->af_smpl); args->af_smpl = NULL; } if ( args->buffer_size ) { args->nbuf_olap = -1; char *end; double tmp = strtod(args->buffer_size,&end); if ( *end ) { if ( *end!=',') error("Could not parse: --buffer-size %s\n", args->buffer_size); args->nbuf_olap = strtol(end+1,&end,10); if ( *end || args->nbuf_olap<0 ) error("Could not parse: --buffer-size %s\n", args->buffer_size); } if ( tmp<0 ) args->nbuf_max = fabs(tmp)*1e6/(4+8*2)/args->roh_smpl->n; else args->nbuf_max = tmp; if ( args->nbuf_olap<0 ) args->nbuf_olap = args->nbuf_max*0.01; } fprintf(stderr,"Number of target samples: %d\n", args->roh_smpl->n); fprintf(stderr,"Number of --estimate-AF samples: %d\n", args->af_smpl ? args->af_smpl->n : (args->estimate_AF ? bcf_hdr_nsamples(args->hdr) : 0)); fprintf(stderr,"Number of sites in the buffer/overlap: "); if ( args->nbuf_max ) fprintf(stderr,"%d/%d\n", args->nbuf_max,args->nbuf_olap); else fprintf(stderr,"unlimited\n"); args->smpl = (smpl_t*) calloc(args->roh_smpl->n,sizeof(smpl_t)); for (i=0; i<256; i++) args->pl2p[i] = pow(10., -i/10.); // Init transition matrix and HMM double tprob[4]; MAT(tprob,2,STATE_HW,STATE_HW) = 1 - args->t2AZ; MAT(tprob,2,STATE_HW,STATE_AZ) = args->t2HW; MAT(tprob,2,STATE_AZ,STATE_HW) = args->t2AZ; MAT(tprob,2,STATE_AZ,STATE_AZ) = 1 - args->t2HW; args->hmm = hmm_init(2, tprob, 10000); if ( args->genmap_fname ) hmm_set_tprob_func(args->hmm, set_tprob_genmap, args); else if ( args->rec_rate > 0 ) hmm_set_tprob_func(args->hmm, set_tprob_rrate, args); args->out = bgzf_open(strcmp("stdout",args->output_fname)?args->output_fname:"-", args->output_type&OUTPUT_GZ ? "wg" : "wu"); if ( !args->out ) error("Failed to open %s: %s\n", args->output_fname, strerror(errno)); // print header args->str.l = 0; ksprintf(&args->str, "# This file was produced by: bcftools roh(%s+htslib-%s)\n", bcftools_version(),hts_version()); ksprintf(&args->str, "# The command line was:\tbcftools %s", args->argv[0]); for (i=1; iargc; i++) ksprintf(&args->str, " %s",args->argv[i]); ksprintf(&args->str, "\n#\n"); if ( args->output_type & OUTPUT_RG ) { i = 2; ksprintf(&args->str, "# RG"); ksprintf(&args->str, "\t[%d]Sample", i++); ksprintf(&args->str, "\t[%d]Chromosome", i++); ksprintf(&args->str, "\t[%d]Start", i++); ksprintf(&args->str, "\t[%d]End", i++); ksprintf(&args->str, "\t[%d]Length (bp)", i++); ksprintf(&args->str, "\t[%d]Number of markers", i++); ksprintf(&args->str, "\t[%d]Quality (average fwd-bwd phred score)", i++); ksprintf(&args->str, "\n"); } if ( args->output_type & OUTPUT_ST ) { i = 2; ksprintf(&args->str, "# ST"); ksprintf(&args->str, "\t[%d]Sample", i++); ksprintf(&args->str, "\t[%d]Chromosome", i++); ksprintf(&args->str, "\t[%d]Position", i++); ksprintf(&args->str, "\t[%d]State (0:HW, 1:AZ)", i++); ksprintf(&args->str, "\t[%d]Quality (fwd-bwd phred score)", i++); ksprintf(&args->str, "\n"); } if ( args->vi_training) { i = 2; ksprintf(&args->str, "# VT, Viterbi Training"); ksprintf(&args->str, "\t[%d]Sample", i++); ksprintf(&args->str, "\t[%d]Iteration", i++); ksprintf(&args->str, "\t[%d]dAZ", i++); ksprintf(&args->str, "\t[%d]dHW", i++); ksprintf(&args->str, "\t[%d]1 - P(HW|HW)", i++); ksprintf(&args->str, "\t[%d]P(AZ|HW)", i++); ksprintf(&args->str, "\t[%d]1 - P(AZ|AZ)", i++); ksprintf(&args->str, "\t[%d]P(HW|AZ)", i++); ksprintf(&args->str, "\n"); } if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); } static void destroy_data(args_t *args) { if ( args->filter ) filter_destroy(args->filter); if ( bgzf_close(args->out)!=0 ) error("Error: close failed .. %s\n", args->output_fname); int i; for (i=0; iroh_smpl->n; i++) { free(args->smpl[i].eprob); free(args->smpl[i].sites); free(args->smpl[i].rid); free(args->smpl[i].rid_off); free(args->smpl[i].snapshot); } free(args->str.s); free(args->smpl); if ( args->af_smpl ) smpl_ilist_destroy(args->af_smpl); smpl_ilist_destroy(args->roh_smpl); free(args->rids); free(args->rid_offs); hmm_destroy(args->hmm); bcf_sr_destroy(args->files); free(args->AFs); free(args->pdg); free(args->genmap); free(args->itmp); free(args->samples); } static int load_genmap(args_t *args, const char *chr) { if ( !args->genmap_fname ) { args->ngenmap = 0; return 0; } kstring_t str = {0,0,0}; char *fname = strstr(args->genmap_fname,"{CHROM}"); if ( fname ) { kputsn(args->genmap_fname, fname - args->genmap_fname, &str); kputs(chr, &str); kputs(fname+7,&str); fname = str.s; } else fname = args->genmap_fname; htsFile *fp = hts_open(fname, "rb"); if ( !fp ) { args->ngenmap = 0; return -1; } hts_getline(fp, KS_SEP_LINE, &str); if ( strcmp(str.s,"position COMBINED_rate(cM/Mb) Genetic_Map(cM)") ) error("Unexpected header in %s, found:\n\t[%s], but expected:\n\t[position COMBINED_rate(cM/Mb) Genetic_Map(cM)]\n", fname, str.s); args->ngenmap = args->igenmap = 0; while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 ) { args->ngenmap++; hts_expand(genmap_t,args->ngenmap,args->mgenmap,args->genmap); genmap_t *gm = &args->genmap[args->ngenmap-1]; // position, convert to 0-based char *tmp, *end; gm->pos = strtol(str.s, &tmp, 10); if ( str.s==tmp ) error("Could not parse %s: %s\n", fname, str.s); gm->pos -= 1; // skip second column tmp++; while ( *tmp && !isspace(*tmp) ) tmp++; // read the genetic map in cM, scale from % to likelihood gm->rate = strtod(tmp+1, &end); if ( tmp+1==end ) error("Could not parse %s: %s\n", fname, str.s); gm->rate *= 0.01; } if ( !args->ngenmap ) error("Genetic map empty?\n"); if ( hts_close(fp) ) error("Close failed\n"); free(str.s); return 0; } static double get_genmap_rate(args_t *args, int start, int end) { // position i to be equal to or smaller than start int i = args->igenmap; if ( args->genmap[i].pos > start ) { while ( i>0 && args->genmap[i].pos > start ) i--; } else { while ( i+1ngenmap && args->genmap[i+1].pos < start ) i++; } // position j to be equal or larger than end int j = i; while ( j+1ngenmap && args->genmap[j].pos < end ) j++; if ( i==j ) { args->igenmap = i; return 0; } if ( start < args->genmap[i].pos ) start = args->genmap[i].pos; if ( end > args->genmap[j].pos ) end = args->genmap[j].pos; double rate = (args->genmap[j].rate - args->genmap[i].rate)/(args->genmap[j].pos - args->genmap[i].pos) * (end-start); args->igenmap = j; return rate; } void set_tprob_genmap(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob) { args_t *args = (args_t*) data; double ci = get_genmap_rate(args, prev_pos, pos); if ( args->rec_rate ) ci *= args->rec_rate; if ( ci > 1 ) ci = 1; MAT(tprob,2,STATE_HW,STATE_AZ) *= ci; MAT(tprob,2,STATE_AZ,STATE_HW) *= ci; MAT(tprob,2,STATE_AZ,STATE_AZ) = 1 - MAT(tprob,2,STATE_HW,STATE_AZ); MAT(tprob,2,STATE_HW,STATE_HW) = 1 - MAT(tprob,2,STATE_AZ,STATE_HW); } void set_tprob_rrate(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob) { args_t *args = (args_t*) data; double ci = (pos - prev_pos) * args->rec_rate; if ( ci > 1 ) ci = 1; MAT(tprob,2,STATE_HW,STATE_AZ) *= ci; MAT(tprob,2,STATE_AZ,STATE_HW) *= ci; MAT(tprob,2,STATE_AZ,STATE_AZ) = 1 - MAT(tprob,2,STATE_HW,STATE_AZ); MAT(tprob,2,STATE_HW,STATE_HW) = 1 - MAT(tprob,2,STATE_AZ,STATE_HW); } /** * This function implements the HMM model: * D = Data, AZ = autozygosity, HW = Hardy-Weinberg (non-autozygosity), * f = non-ref allele frequency * * Emission probabilities: * oAZ = P_i(D|AZ) = (1-f)*P(D|RR) + f*P(D|AA) * oHW = P_i(D|HW) = (1-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1-f)*P(D|RA) * * Transition probabilities: * tAZ = P(AZ|HW) .. parameter * tHW = P(HW|AZ) .. parameter * * ci = P_i(C) .. probability of cross-over at site i, from genetic map * * AZi = P_i(AZ) .. probability of site i being AZ/non-AZ, scaled so that AZi+HWi = 1 * HWi = P_i(HW) * * P_i(AZ|HW) = P(AZ|HW) * ci * HW{i-1} = tAZ * ci * (1 - AZ{i-1}) * P_i(HW|AZ) = P(HW|AZ) * ci * AZ{i-1} = tHW * ci * AZ{i-1} * P_i(AZ|AZ) = 1 - P_i(HW|AZ) * P_i(HW|HW) = 1 - P_i(AZ|HW) * */ static void flush_viterbi(args_t *args, int ismpl) { smpl_t *smpl = &args->smpl[ismpl]; if ( !smpl->nsites ) return; const char *name = args->hdr->samples[ args->roh_smpl->idx[ismpl] ]; int i,j,k; if ( !args->vi_training ) // single viterbi pass { hmm_restore(args->hmm, smpl->snapshot); int end = (args->nbuf_max && smpl->nsites >= args->nbuf_max && smpl->nsites > args->nbuf_olap) ? smpl->nsites - args->nbuf_olap : smpl->nsites; if ( end < smpl->nsites ) smpl->snapshot = hmm_snapshot(args->hmm, smpl->snapshot, smpl->sites[smpl->nsites - args->nbuf_olap - 1]); args->igenmap = smpl->igenmap; hmm_run_viterbi(args->hmm, smpl->nsites, smpl->eprob, smpl->sites); hmm_run_fwd_bwd(args->hmm, smpl->nsites, smpl->eprob, smpl->sites); double *fwd = hmm_get_fwd_bwd_prob(args->hmm); const char *chr = bcf_hdr_id2name(args->hdr,args->prev_rid); uint8_t *vpath = hmm_get_viterbi_path(args->hmm); for (i=0; ioutput_type & OUTPUT_ST ) { args->str.l = 0; ksprintf(&args->str, "ST\t%s\t%s\t%d\t%d\t%.1f\n", name,chr,smpl->sites[i]+1, state, qual); if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); } if ( args->output_type & OUTPUT_RG ) { if ( state!=smpl->rg.state ) { if ( !state ) // the region ends, flush { args->str.l = 0; ksprintf(&args->str, "RG\t%s\t%s\t%d\t%d\t%d\t%d\t%.1f\n",name,bcf_hdr_id2name(args->hdr,smpl->rg.rid), smpl->rg.beg+1,smpl->rg.end+1,smpl->rg.end-smpl->rg.beg+1,smpl->rg.nqual,smpl->rg.qual/smpl->rg.nqual); if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); smpl->rg.state = 0; } else { smpl->rg.state = 1; smpl->rg.beg = smpl->sites[i]; smpl->rg.end = smpl->sites[i]; smpl->rg.rid = args->prev_rid; smpl->rg.qual = qual; smpl->rg.nqual = 1; } } else if ( state ) { smpl->rg.nqual++; smpl->rg.qual += qual; smpl->rg.end = smpl->sites[i]; } } } if ( end < smpl->nsites ) { end = smpl->nsites - args->nbuf_olap; memmove(smpl->sites, smpl->sites + end, sizeof(*smpl->sites)*args->nbuf_olap); memmove(smpl->eprob, smpl->eprob + end*2, sizeof(*smpl->eprob)*args->nbuf_olap*2); smpl->nsites = args->nbuf_olap; smpl->igenmap = args->igenmap; } else { smpl->nsites = 0; smpl->igenmap = 0; if ( smpl->rg.state ) { args->str.l = 0; ksprintf(&args->str, "RG\t%s\t%s\t%d\t%d\t%d\t%d\t%.1f\n",name,bcf_hdr_id2name(args->hdr,smpl->rg.rid), smpl->rg.beg+1,smpl->rg.end+1,smpl->rg.end-smpl->rg.beg+1,smpl->rg.nqual,smpl->rg.qual/smpl->rg.nqual); if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); smpl->rg.state = 0; } } return; } // viterbi training, multiple chromosomes double t2az_prev, t2hw_prev; double deltaz, delthw; double *tprob_arr = hmm_get_tprob(args->hmm); MAT(tprob_arr,2,STATE_HW,STATE_HW) = 1 - args->t2AZ; MAT(tprob_arr,2,STATE_HW,STATE_AZ) = args->t2HW; MAT(tprob_arr,2,STATE_AZ,STATE_HW) = args->t2AZ; MAT(tprob_arr,2,STATE_AZ,STATE_AZ) = 1 - args->t2HW; hmm_set_tprob(args->hmm, tprob_arr, 10000); int niter = 0; do { tprob_arr = hmm_get_tprob(args->hmm); t2az_prev = MAT(tprob_arr,2,STATE_AZ,STATE_HW); //args->t2AZ; t2hw_prev = MAT(tprob_arr,2,STATE_HW,STATE_AZ); //args->t2HW; double tprob_new[] = { 0,0,0,0 }; for (i=0; inrid; i++) { int ioff = smpl->rid_off[i]; int nsites = (i+1==smpl->nrid ? smpl->nsites : smpl->rid_off[i+1]) - ioff; args->igenmap = 0; tprob_arr = hmm_run_baum_welch(args->hmm, nsites, smpl->eprob+ioff*2, smpl->sites+ioff); for (j=0; j<2; j++) for (k=0; k<2; k++) MAT(tprob_new,2,j,k) += MAT(tprob_arr,2,j,k); } for (j=0; j<2; j++) for (k=0; k<2; k++) MAT(tprob_new,2,j,k) /= smpl->nrid; hmm_set_tprob(args->hmm, tprob_new, 10000); deltaz = fabs(MAT(tprob_new,2,STATE_AZ,STATE_HW)-t2az_prev); delthw = fabs(MAT(tprob_new,2,STATE_HW,STATE_AZ)-t2hw_prev); niter++; args->str.l = 0; ksprintf(&args->str, "VT\t%s\t%d\t%e\t%e\t%e\t%e\t%e\t%e\n", name,niter,deltaz,delthw, 1-MAT(tprob_new,2,STATE_HW,STATE_HW),MAT(tprob_new,2,STATE_AZ,STATE_HW), 1-MAT(tprob_new,2,STATE_AZ,STATE_AZ),MAT(tprob_new,2,STATE_HW,STATE_AZ)); if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); } while ( deltaz > args->baum_welch_th || delthw > args->baum_welch_th ); // output the results for (i=0; inrid; i++) { int ioff = smpl->rid_off[i]; int nsites = (i+1==smpl->nrid ? smpl->nsites : smpl->rid_off[i+1]) - ioff; args->igenmap = 0; hmm_run_viterbi(args->hmm, nsites, smpl->eprob+ioff*2, smpl->sites+ioff); hmm_run_fwd_bwd(args->hmm, nsites, smpl->eprob+ioff*2, smpl->sites+ioff); uint8_t *vpath = hmm_get_viterbi_path(args->hmm); double *fwd = hmm_get_fwd_bwd_prob(args->hmm); const char *chr = bcf_hdr_id2name(args->hdr,smpl->rid[i]); for (j=0; jstr.l = 0; ksprintf(&args->str, "ROH\t%s\t%s\t%d\t%d\t%.1f\n", name,chr,smpl->sites[ioff+j]+1, state, phred_score(1.0-pval[state])); if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); } } } int read_AF(bcf_sr_regions_t *tgt, bcf1_t *line, double *alt_freq) { if ( tgt->nals < 2 ) error("Expected two comma-separated alleles (REF,ALT) in the third column of %s, found:\n\t%s\n", tgt->fname,tgt->line.s); if ( tgt->nals != line->n_allele ) return -1; // number of alleles does not match int i; for (i=0; inals; i++) if ( strcmp(line->d.allele[i],tgt->als[i]) ) break; // we could be smarter, see vcmp if ( inals ) return -1; char *tmp, *str = tgt->line.s; i = 0; while ( *str && i<3 ) { if ( *str=='\t' ) i++; str++; } *alt_freq = strtod(str, &tmp); if ( *tmp && !isspace(*tmp) ) { if ( str[0]=='.' && (!str[1] || isspace(str[1])) ) return -1; // missing value error("Could not parse: [%s]\n", tgt->line.s); } if ( *alt_freq<0 || *alt_freq>1 ) error("Could not parse AF: [%s]\n", tgt->line.s); return 0; } int8_t *get_GT(args_t *args, bcf1_t *line) { int i; for (i=0; in_fmt; i++) if ( line->d.fmt[i].id==args->gt_hdr_id ) break; if ( i==line->n_fmt ) return NULL; // the tag is not present in this record bcf_fmt_t *fmt = &line->d.fmt[i]; if ( fmt->n!=2 ) return NULL; // not diploid if ( fmt->type!=BCF_BT_INT8 ) error("This is unexpected, GT type is %d\n", fmt->type); return (int8_t*) fmt->p; } int estimate_AF_from_GT(args_t *args, int8_t *gt, double *alt_freq) { int i, nalt = 0, nref = 0; if ( args->af_smpl ) // subset samples for AF estimate { for (i=0; iaf_smpl->n; i++) { int ismpl = args->af_smpl->idx[i]; if ( bcf_gt_is_missing(gt[2*ismpl]) || bcf_gt_is_missing(gt[2*ismpl+1]) ) continue; if ( bcf_gt_allele(gt[2*ismpl]) ) nalt++; else nref++; if ( bcf_gt_allele(gt[2*ismpl+1]) ) nalt++; else nref++; } } else // all samples used in AF estimate { int8_t *end = gt + 2*bcf_hdr_nsamples(args->hdr); while ( gt < end ) { if ( bcf_gt_is_missing(gt[0]) || bcf_gt_is_missing(gt[1]) ) { gt += 2; continue; } if ( bcf_gt_allele(gt[0]) ) nalt++; else nref++; if ( bcf_gt_allele(gt[1]) ) nalt++; else nref++; gt += 2; } } if ( !nalt && !nref ) return -1; *alt_freq = (double)nalt / (nalt + nref); return 0; } int estimate_AF_from_PL(args_t *args, bcf_fmt_t *fmt_pl, int ial, double *alt_freq) { double af = 0; int i, j, naf = 0; int irr = bcf_alleles2gt(0,0), ira = bcf_alleles2gt(0,ial), iaa = bcf_alleles2gt(ial,ial); if ( iaa >= fmt_pl->n ) return -1; // not diploid or wrong number of fields if ( args->af_smpl ) // subset samples for AF estimate { #define BRANCH(type_t) \ { \ for (i=0; iaf_smpl->n; i++) \ { \ int ismpl = args->af_smpl->idx[i]; \ type_t *p = (type_t*)fmt_pl->p + fmt_pl->n*ismpl; \ if ( p[irr]<0 || p[ira]<0 || p[iaa]<0 ) continue; /* missing value */ \ if ( p[irr]==p[ira] && p[irr]==p[iaa] ) continue; /* all values are the same */ \ double prob[3], norm = 0; \ prob[0] = args->pl2p[ max255(p[irr]) ]; \ prob[1] = args->pl2p[ max255(p[ira]) ]; \ prob[2] = args->pl2p[ max255(p[iaa]) ]; \ for (j=0; j<3; j++) norm += prob[j]; \ for (j=0; j<3; j++) prob[j] /= norm; \ af += 0.5*prob[1] + prob[2]; \ naf++; \ } \ } switch (fmt_pl->type) { case BCF_BT_INT8: BRANCH(int8_t); break; case BCF_BT_INT16: BRANCH(int16_t); break; case BCF_BT_INT32: BRANCH(int32_t); break; default: fprintf(stderr,"Unknown format type for PL: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt_pl->type); exit(1); } #undef BRANCH } else // all samples used in AF estimate { int nsmpl = bcf_hdr_nsamples(args->hdr); #define BRANCH(type_t) \ { \ type_t *p = (type_t*)fmt_pl->p; \ p -= fmt_pl->n; \ for (i=0; in; \ if ( p[irr]<0 || p[ira]<0 || p[iaa]<0 ) continue; /* missing value */ \ if ( p[irr]==p[ira] && p[irr]==p[iaa] ) continue; /* all values are the same */ \ double prob[3], norm = 0; \ prob[0] = args->pl2p[ max255(p[irr]) ]; \ prob[1] = args->pl2p[ max255(p[ira]) ]; \ prob[2] = args->pl2p[ max255(p[iaa]) ]; \ for (j=0; j<3; j++) norm += prob[j]; \ for (j=0; j<3; j++) prob[j] /= norm; \ af += 0.5*prob[1] + prob[2]; \ naf++; \ } \ } switch (fmt_pl->type) { case BCF_BT_INT8: BRANCH(int8_t); break; case BCF_BT_INT16: BRANCH(int16_t); break; case BCF_BT_INT32: BRANCH(int32_t); break; default: fprintf(stderr,"Unknown format type for PL: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt_pl->type); exit(1); } #undef BRANCH } if ( !naf ) return -1; *alt_freq = af / naf; return 0; } bcf_fmt_t *get_PL(args_t *args, bcf1_t *line) { int i; for (i=0; in_fmt; i++) if ( line->d.fmt[i].id==args->pl_hdr_id ) return &line->d.fmt[i]; return NULL; } int process_line(args_t *args, bcf1_t *line, int ial) { if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); double alt_freq; int8_t *GTs = NULL; bcf_fmt_t *fmt_pl = NULL; // Set allele frequency int ret = 0, i,j; if ( args->af_tag ) { // Use an INFO tag provided by the user ret = bcf_get_info_float(args->hdr, line, args->af_tag, &args->AFs, &args->mAFs); if ( ret>0 ) alt_freq = args->AFs[ial-1]; if ( ret==-2 ) error("Type mismatch for INFO/%s tag at %s:%"PRId64"\n", args->af_tag, bcf_seqname(args->hdr,line), (int64_t) line->pos+1); } else if ( args->af_fname ) { // Read AF from a file ret = read_AF(args->files->targets, line, &alt_freq); } else if ( args->dflt_AF > 0 ) { alt_freq = args->dflt_AF; } else if ( args->estimate_AF ) { // Estimate AF from GTs or PLs of all samples or samples listed in a file if ( args->af_from_PL ) { fmt_pl = get_PL(args, line); if ( !fmt_pl ) return -1; ret = estimate_AF_from_PL(args, fmt_pl, ial, &alt_freq); } else { GTs = get_GT(args, line); if ( !GTs ) return -1; ret = estimate_AF_from_GT(args, GTs, &alt_freq); } } else { // Use AC/AN int AC = -1, AN = 0; ret = bcf_get_info_int32(args->hdr, line, "AN", &args->itmp, &args->mitmp); if ( ret==1 ) { AN = args->itmp[0]; ret = bcf_get_info_int32(args->hdr, line, "AC", &args->itmp, &args->mitmp); if ( ret>0 ) AC = args->itmp[0]; } if ( AN<=0 || AC<0 ) ret = -1; else alt_freq = (double) AC/AN; } if ( args->dflt_AF>0 && (ret<0 || alt_freq==0.0) ) alt_freq = args->dflt_AF; else if ( ret<0 ) { args->nno_af++; return ret; } else if ( alt_freq==0.0 ) { args->nno_af++; return -1; } int irr = bcf_alleles2gt(0,0), ira = bcf_alleles2gt(0,ial), iaa = bcf_alleles2gt(ial,ial); if ( args->fake_PLs ) { if ( !GTs ) GTs = get_GT(args, line); } else { fmt_pl = get_PL(args, line); if ( !fmt_pl ) return -1; if ( iaa >= fmt_pl->n ) return -1; // not diploid or wrong number of fields } for (i=0; iroh_smpl->n; i++) { int ismpl = args->roh_smpl->idx[i]; // set P(D|G) double pdg[3]; if ( args->fake_PLs ) { int8_t *gt = GTs + 2*ismpl; if ( bcf_gt_is_missing(gt[0]) || bcf_gt_is_missing(gt[1]) ) continue; int a = bcf_gt_allele(gt[0]); int b = bcf_gt_allele(gt[1]); if ( a!=b ) { pdg[0] = pdg[2] = args->unseen_PL; pdg[1] = 1 - 2*args->unseen_PL; } else if ( a==0 ) { pdg[0] = 1 - args->unseen_PL - args->unseen_PL*args->unseen_PL; pdg[1] = args->unseen_PL; pdg[2] = args->unseen_PL*args->unseen_PL; } else { pdg[0] = args->unseen_PL*args->unseen_PL; pdg[1] = args->unseen_PL; pdg[2] = 1 - args->unseen_PL - args->unseen_PL*args->unseen_PL; } } else { #define BRANCH(type_t) \ { \ type_t *p = (type_t*)fmt_pl->p + fmt_pl->n*ismpl; \ if ( p[irr]<0 || p[ira]<0 || p[iaa]<0 ) continue; /* missing value */ \ if ( p[irr]==p[ira] && p[irr]==p[iaa] ) continue; /* all values are the same */ \ pdg[0] = args->pl2p[ max255(p[irr]) ]; \ pdg[1] = args->pl2p[ max255(p[ira]) ]; \ pdg[2] = args->pl2p[ max255(p[iaa]) ]; \ } switch (fmt_pl->type) { case BCF_BT_INT8: BRANCH(int8_t); break; case BCF_BT_INT16: BRANCH(int16_t); break; case BCF_BT_INT32: BRANCH(int32_t); break; default: fprintf(stderr,"Unknown format type for PL: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt_pl->type); exit(1); } #undef BRANCH } double sum = pdg[0] + pdg[1] + pdg[2]; if ( !sum ) continue; for (j=0; j<3; j++) pdg[j] /= sum; if ( args->skip_homref && pdg[0]>0.99 ) continue; smpl_t *smpl = &args->smpl[i]; smpl->nused++; if ( smpl->nsites >= smpl->msites ) { hts_expand(uint32_t,smpl->nsites+1,smpl->msites,smpl->sites); smpl->eprob = (double*) realloc(smpl->eprob,sizeof(*smpl->eprob)*smpl->msites*2); if ( !smpl->eprob ) error("Error: failed to alloc %"PRIu64" bytes\n", (uint64_t)(sizeof(*smpl->eprob)*smpl->msites*2)); } // Calculate emission probabilities P(D|AZ) and P(D|HW) double *eprob = &smpl->eprob[2*smpl->nsites]; eprob[STATE_AZ] = pdg[0]*(1-alt_freq) + pdg[2]*alt_freq; eprob[STATE_HW] = pdg[0]*(1-alt_freq)*(1-alt_freq) + 2*pdg[1]*(1-alt_freq)*alt_freq + pdg[2]*alt_freq*alt_freq; smpl->sites[smpl->nsites] = line->pos; smpl->nsites++; if ( args->vi_training ) { if ( !smpl->nrid || line->rid!=smpl->rid[smpl->nrid-1] ) { smpl->nrid++; smpl->rid = (int*) realloc(smpl->rid,sizeof(*smpl->rid)*smpl->nrid); smpl->rid[smpl->nrid-1] = line->rid; smpl->rid_off = (int*) realloc(smpl->rid_off,sizeof(*smpl->rid_off)*smpl->nrid); smpl->rid_off[smpl->nrid-1] = smpl->nsites - 1; } } else if ( args->nbuf_max && smpl->nsites >= args->nbuf_max ) flush_viterbi(args, i); } return 0; } static void vcfroh(args_t *args, bcf1_t *line) { int i; // Are we done? if ( !line ) { for (i=0; iroh_smpl->n; i++) flush_viterbi(args, i); return; } // Skip unwanted lines, for simplicity we consider only biallelic sites if ( line->rid == args->skip_rid ) return; // This can be raw callable VCF with the symbolic unseen allele <*> int ial = 0, nalt = line->n_allele - 1; for (i=1; in_allele; i++) { if ( !strcmp("<*>",line->d.allele[i]) || !strcmp("",line->d.allele[i]) ) nalt--; else if ( !ial ) ial = i; } if ( !nalt ) // no ALT allele { args->nno_alt++; if ( !args->include_noalt_sites ) return; } else if ( nalt>1 ) { args->nmultiallelic++; return; } if ( args->snps_only && !bcf_is_snp(line) ) return; // Initialize genetic map int skip_rid = 0; if ( args->prev_rid<0 ) skip_rid = load_genmap(args, bcf_seqname(args->hdr,line)); // New chromosome? if ( args->prev_rid!=line->rid ) { if ( !args->vi_training ) { for (i=0; iroh_smpl->n; i++) { flush_viterbi(args, i); hmm_reset(args->hmm, args->smpl[i].snapshot); } } args->prev_rid = line->rid; args->prev_pos = line->pos; skip_rid = load_genmap(args, bcf_seqname(args->hdr,line)); } else if ( args->prev_pos == line->pos ) { args->ndup++; return; // skip duplicate positions } if ( skip_rid ) { fprintf(stderr,"Skipping the sequence, no genmap for %s\n", bcf_seqname(args->hdr,line)); args->skip_rid = line->rid; return; } if ( args->prev_pos > line->pos ) error("The file is not sorted?!\n"); args->prev_rid = line->rid; args->prev_pos = line->pos; // parse the new line process_line(args, line, ial); } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: HMM model for detecting runs of autozygosity.\n"); fprintf(stderr, "Usage: bcftools roh [options] \n"); fprintf(stderr, "\n"); fprintf(stderr, "General Options:\n"); fprintf(stderr, " --AF-dflt if AF is not known, use this allele frequency [skip]\n"); fprintf(stderr, " --AF-tag use TAG for allele frequency\n"); fprintf(stderr, " --AF-file read allele frequencies from file (CHR\\tPOS\\tREF,ALT\\tAF)\n"); fprintf(stderr, " -b --buffer-size buffer size and the number of overlapping sites, 0 for unlimited [0]\n"); fprintf(stderr, " If the first number is negative, it is interpreted as the maximum memory to\n"); fprintf(stderr, " use, in MB. The default overlap is set to roughly 1%% of the buffer size.\n"); fprintf(stderr, " -e, --estimate-AF [TAG], estimate AF from FORMAT/TAG (GT or PL) of all samples (\"-\") or samples listed\n"); fprintf(stderr, " in . If TAG is not given, the frequency is estimated from GT by default\n"); fprintf(stderr, " --exclude exclude sites for which the expression is true\n"); fprintf(stderr, " -G, --GTs-only use GTs and ignore PLs, instead using for PL of the two least likely genotypes.\n"); fprintf(stderr, " Safe value to use is 30 to account for GT errors.\n"); fprintf(stderr, " --include select sites for which the expression is true\n"); fprintf(stderr, " -i, --ignore-homref skip hom-ref genotypes (0/0)\n"); fprintf(stderr, " --include-noalt include sites with no ALT allele (ignored by default)\n"); fprintf(stderr, " -I, --skip-indels skip indels as their genotypes are enriched for errors\n"); fprintf(stderr, " -m, --genetic-map genetic map in IMPUTE2 format, single file or mask, where string \"{CHROM}\"\n"); fprintf(stderr, " is replaced with chromosome name\n"); fprintf(stderr, " -M, --rec-rate constant recombination rate per bp\n"); fprintf(stderr, " -o, --output write output to a file [standard output]\n"); fprintf(stderr, " -O, --output-type [srz] output s:per-site, r:regions, z:compressed [sr]\n"); fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples list of samples to analyze [all samples]\n"); fprintf(stderr, " -S, --samples-file file of samples to analyze [all samples]\n"); fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " --threads use multithreading with worker threads [0]\n"); fprintf(stderr, "\n"); fprintf(stderr, "HMM Options:\n"); fprintf(stderr, " -a, --hw-to-az P(AZ|HW) transition probability from HW (Hardy-Weinberg) to AZ (autozygous) state [6.7e-8]\n"); fprintf(stderr, " -H, --az-to-hw P(HW|AZ) transition probability from AZ to HW state [5e-9]\n"); fprintf(stderr, " -V, --viterbi-training estimate HMM parameters, is the convergence threshold, e.g. 1e-10 (experimental)\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfroh(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->files = bcf_sr_init(); args->t2AZ = 6.7e-8; args->t2HW = 5e-9; args->rec_rate = 0; int regions_is_file = 0, targets_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; static struct option loptions[] = { {"AF-tag",1,0,0}, {"AF-file",1,0,1}, {"AF-dflt",1,0,2}, {"include",1,0,3}, {"exclude",1,0,4}, {"include-noalt",0,0,5}, {"buffer-size",1,0,'b'}, {"ignore-homref",0,0,'i'}, {"estimate-AF",1,0,'e'}, {"output",1,0,'o'}, {"output-type",1,0,'O'}, {"GTs-only",1,0,'G'}, {"samples",1,0,'s'}, {"samples-file",1,0,'S'}, {"hw-to-az",1,0,'a'}, {"az-to-hw",1,0,'H'}, {"viterbi-training",1,0,'V'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,6}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,7}, {"genetic-map",1,0,'m'}, {"rec-rate",1,0,'M'}, {"skip-indels",0,0,'I'}, {"threads",1,0,9}, {0,0,0,0} }; int naf_opts = 0; char *tmp; while ((c = getopt_long(argc, argv, "h?r:R:t:T:H:a:s:S:m:M:G:Ia:e:V:b:O:o:i",loptions,NULL)) >= 0) { switch (c) { case 0: args->af_tag = optarg; naf_opts++; break; case 1: args->af_fname = optarg; naf_opts++; break; case 2: args->dflt_AF = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --AF-dflt %s\n", optarg); break; case 3 : if ( args->filter_str ) error("Error: only one --include or --exclude expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 4 : if ( args->filter_str ) error("Error: only one --include or --exclude expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 5: args->include_noalt_sites = 1; break; case 'o': args->output_fname = optarg; break; case 'O': if ( strchr(optarg,'s') || strchr(optarg,'S') ) args->output_type |= OUTPUT_ST; if ( strchr(optarg,'r') || strchr(optarg,'R') ) args->output_type |= OUTPUT_RG; if ( strchr(optarg,'z') || strchr(optarg,'z') ) args->output_type |= OUTPUT_GZ; break; case 'e': args->estimate_AF = optarg; naf_opts++; break; case 'b': args->buffer_size = optarg; break; case 'i': args->skip_homref = 1; break; case 'I': args->snps_only = 1; break; case 'G': args->fake_PLs = 1; args->unseen_PL = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -G %s\n", optarg); args->unseen_PL = pow(10,-args->unseen_PL/10.); break; case 'm': args->genmap_fname = optarg; break; case 'M': args->rec_rate = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -M %s\n", optarg); break; case 's': args->samples = strdup(optarg); break; case 'S': args->samples = strdup(optarg); args->samples_is_file = 1; break; case 'a': args->t2AZ = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -a %s\n", optarg); break; case 'H': args->t2HW = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: -H %s\n", optarg); break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 6 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 7 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 'V': args->vi_training = 1; args->baum_welch_th = strtod(optarg,&tmp); if ( *tmp ) error("Could not parse: --viterbi-training %s\n", optarg); break; case 'h': case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } if ( !args->output_fname ) args->output_fname = "stdout"; if ( !args->output_type || args->output_type==OUTPUT_GZ ) args->output_type |= OUTPUT_ST|OUTPUT_RG; char *fname = NULL; if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(args); } else fname = argv[optind]; if ( args->vi_training && args->buffer_size ) error("Error: cannot use -b with -V\n"); if ( args->t2AZ<0 || args->t2AZ>1 ) error("Error: The parameter --hw-to-az is not in [0,1] .. %e\n", args->t2AZ); if ( args->t2HW<0 || args->t2HW>1 ) error("Error: The parameter --az-to-hw is not in [0,1] .. %e\n", args->t2HW); if ( naf_opts>1 ) error("Error: The options --AF-tag, --AF-file and -e are mutually exclusive\n"); if ( args->af_fname && args->targets_list ) error("Error: The options --AF-file and -t are mutually exclusive\n"); if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( args->af_fname ) { if ( bcf_sr_set_targets(args->files, args->af_fname, 1, 3)<0 ) error("Failed to read the targets: %s\n", args->af_fname); } if ( args->n_threads && bcf_sr_set_threads(args->files, args->n_threads)<0) error("Failed to create threads\n"); if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); init_data(args); while ( bcf_sr_next_line(args->files) ) { args->ntot++; bcf1_t *line = bcf_sr_get_line(args->files,0); if ( args->filter ) { int pass = filter_test(args->filter, line, NULL); if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; if ( !pass ) { args->nfiltered++; continue; } } vcfroh(args, line); } vcfroh(args, NULL); int i, nmin = 0; for (i=0; iroh_smpl->n; i++) if ( !i || args->smpl[i].nused < nmin ) nmin = args->smpl[i].nused; if ( args->af_fname ) fprintf(stderr,"Number of lines overlapping with --AF-file/processed: %d/%d\n", args->ntot,nmin); else fprintf(stderr,"Number of lines total/processed: %d/%d\n", args->ntot,nmin); fprintf(stderr,"Number of lines filtered/no AF/no alt/multiallelic/dup: %d/%d/%d/%d/%d\n", args->nfiltered,args->nno_af,args->nno_alt,args->nmultiallelic,args->ndup); if ( nmin==0 ) { fprintf(stderr,"No usable sites were found.\n"); if ( !naf_opts && !args->dflt_AF ) fprintf(stderr, " Consider using one of the AF options.\n"); } destroy_data(args); free(args); return 0; } bcftools-1.21/vcfsom.c000066400000000000000000000577131467060157400147400ustar00rootroot00000000000000/* vcfsom.c -- SOM (Self-Organizing Map) filtering. Copyright (C) 2013-2014, 2020 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #define SOM_TRAIN 1 #define SOM_CLASSIFY 2 typedef struct { int ndim; // dimension of the map (2D, 3D, ...) int nbin; // number of bins in th map int size; // pow(nbin,ndim) int kdim; // dimension of the input vectors int nt, t; // total number of learning cycles and the current cycle double *w, *c; // weights and counts (sum of learning influence) double learn; // learning rate double bmu_th; // best-matching unit threshold int *a_idx, *b_idx; // temp arrays for traversing variable number of nested loops double *div; // dtto } som_t; typedef struct { // SOM parameters double bmu_th, learn; int ndim, nbin, ntrain, t; int nfold; // n-fold cross validation = the number of SOMs som_t **som; // annots reader's data htsFile *file; // reader kstring_t str; // temporary string for the reader int dclass, mvals; double *vals; // training data double *train_dat; int *train_class, mtrain_class, mtrain_dat; int rand_seed, good_class, bad_class; char **argv, *fname, *prefix; int argc, action, train_bad, merge; } args_t; static void usage(void); FILE *open_file(char **fname, const char *mode, const char *fmt, ...) HTS_FORMAT(HTS_PRINTF_FMT, 3, 4); char * HTS_FORMAT(HTS_PRINTF_FMT, 1, 2) msprintf(const char *fmt, ...) { va_list ap; va_start(ap, fmt); int n = vsnprintf(NULL, 0, fmt, ap) + 2; va_end(ap); char *str = (char*)malloc(n); va_start(ap, fmt); vsnprintf(str, n, fmt, ap); va_end(ap); return str; } /* * char *t, *p = str; * t = column_next(p, '\t'); * if ( strlen("")==t-p && !strncmp(p,"",t-p) ) printf("found!\n"); * * char *t; * t = column_next(str, '\t'); if ( !*t ) error("expected field\n", str); * t = column_next(t+1, '\t'); if ( !*t ) error("expected field\n", str); */ static inline char *column_next(char *start, char delim) { char *end = start; while (*end && *end!=delim) end++; return end; } /** * annots_reader_next() - reads next line from annots.tab.gz and sets: class, vals * Returns 1 on successful read or 0 if no further record could be read. */ int annots_reader_next(args_t *args) { args->str.l = 0; if ( hts_getline(args->file,'\n',&args->str)<=0 ) return 0; char *t, *line = args->str.s; if ( !args->mvals ) { t = line; while ( *t ) { if ( *t=='\t' ) args->mvals++; t++; } args->vals = (double*) malloc(args->mvals*sizeof(double)); } // class args->dclass = atoi(line); t = column_next(line, '\t'); // values int i; for (i=0; imvals; i++) { if ( !*t ) error("Could not parse %d-th data field: is the line truncated?\nThe line was: [%s]\n",i+2,line); args->vals[i] = atof(++t); t = column_next(t,'\t'); } return 1; } void annots_reader_reset(args_t *args) { if ( args->file ) hts_close(args->file); if ( !args->fname ) error("annots_reader_reset: no fname\n"); args->file = hts_open(args->fname, "r"); } void annots_reader_close(args_t *args) { hts_close(args->file); } static void som_write_map(char *prefix, som_t **som, int nsom) { FILE *fp = open_file(NULL,"w","%s.som",prefix); size_t nw; if ( (nw=fwrite("SOMv1",5,1,fp))!=5 ) error("Failed to write 5 bytes\n"); if ( (nw=fwrite(&nsom,sizeof(int),1,fp))!=sizeof(int) ) error("Failed to write %zu bytes\n",sizeof(int)); int i; for (i=0; isize,sizeof(int),1,fp))!=sizeof(int) ) error("Failed to write %zu bytes\n",sizeof(int)); if ( (nw=fwrite(&som[i]->kdim,sizeof(int),1,fp))!=sizeof(int) ) error("Failed to write %zu bytes\n",sizeof(int)); if ( (nw=fwrite(som[i]->w,sizeof(double),som[i]->size*som[i]->kdim,fp))!=sizeof(double)*som[i]->size*som[i]->kdim ) error("Failed to write %zu bytes\n",sizeof(double)*som[i]->size*som[i]->kdim); if ( (nw=fwrite(som[i]->c,sizeof(double),som[i]->size,fp))!=sizeof(double)*som[i]->size ) error("Failed to write %zu bytes\n",sizeof(double)*som[i]->size); } if ( fclose(fp) ) error("%s.som: fclose failed\n",prefix); } static som_t** som_load_map(char *prefix, int *nsom) { FILE *fp = open_file(NULL,"r","%s.som",prefix); char buf[5]; if ( fread(buf,5,1,fp)!=1 || strncmp(buf,"SOMv1",5) ) error("Could not parse %s.som\n", prefix); if ( fread(nsom,sizeof(int),1,fp)!=1 ) error("Could not read %s.som\n", prefix); som_t **som = (som_t**)malloc(*nsom*sizeof(som_t*)); int i; for (i=0; i<*nsom; i++) { som[i] = (som_t*) calloc(1,sizeof(som_t)); if ( fread(&som[i]->size,sizeof(int),1,fp) != 1 ) error("Could not read %s.som\n", prefix); if ( fread(&som[i]->kdim,sizeof(int),1,fp) != 1 ) error("Could not read %s.som\n", prefix); som[i]->w = (double*) malloc(sizeof(double)*som[i]->size*som[i]->kdim); som[i]->c = (double*) malloc(sizeof(double)*som[i]->size); if ( fread(som[i]->w,sizeof(double),som[i]->size*som[i]->kdim,fp) != som[i]->size*som[i]->kdim ) error("Could not read from %s.som\n", prefix); if ( fread(som[i]->c,sizeof(double),som[i]->size,fp) != som[i]->size ) error("Could not read from %s.som\n", prefix); } if ( fclose(fp) ) error("%s.som: fclose failed\n",prefix); return som; } static void som_create_plot(som_t *som, char *prefix) { if ( som->ndim!=2 ) return; char *fname; FILE *fp = open_file(&fname,"w","%s.py",prefix); fprintf(fp, "import matplotlib as mpl\n" "mpl.use('Agg')\n" "import matplotlib.pyplot as plt\n" "\n" "dat = [\n" ); int i,j; double *val = som->c; for (i=0; inbin; i++) { fprintf(fp,"["); for (j=0; jnbin; j++) { if ( j>0 ) fprintf(fp,","); fprintf(fp,"%e", *val); val++; } fprintf(fp,"],\n"); } fprintf(fp, "]\n" "fig = plt.figure()\n" "ax1 = plt.subplot(111)\n" "im1 = ax1.imshow(dat)\n" "fig.colorbar(im1)\n" "plt.savefig('%s.png')\n" "plt.close()\n" "\n", prefix ); fclose(fp); free(fname); } // Find the best matching unit: the node with minimum distance from the input vector static inline int som_find_bmu(som_t *som, double *vec, double *dist) { double *ptr = som->w; double min_dist = HUGE_VAL; int min_idx = 0; int i, k; for (i=0; isize; i++) { double dist = 0; for (k=0; kkdim; k++) dist += (vec[k] - ptr[k]) * (vec[k] - ptr[k]); if ( dist < min_dist ) { min_dist = dist; min_idx = i; } ptr += som->kdim; } if ( dist ) *dist = min_dist; return min_idx; } static inline double som_get_score(som_t *som, double *vec, double bmu_th) { double *ptr = som->w; double min_dist = HUGE_VAL; int i, k; for (i=0; isize; i++) { if ( som->c[i] >= bmu_th ) { double dist = 0; for (k=0; kkdim; k++) dist += (vec[k] - ptr[k]) * (vec[k] - ptr[k]); if ( dist < min_dist ) min_dist = dist; } ptr += som->kdim; } return sqrt(min_dist); } // Convert flat index to that of a k-dimensional cube static inline void som_idx_to_ndim(som_t *som, int idx, int *ndim) { int i; double sub = 0; ndim[0] = idx/som->div[0]; for (i=1; indim; i++) { sub += ndim[i-1] * som->div[i-1]; ndim[i] = (idx - sub)/som->div[i]; } } static void som_train_site(som_t *som, double *vec, int update_counts) { // update learning rate and learning radius som->t++; double dt = exp(-som->t/som->nt); double learning_rate = som->learn * dt; double radius = som->nbin * dt; radius *= radius; // find the best matching unit and its indexes int min_idx = som_find_bmu(som, vec, NULL); som_idx_to_ndim(som, min_idx, som->a_idx); // update the weights: traverse the map and make all nodes within the // radius more similar to the input vector double *ptr = som->w; double *cnt = som->c; int i, j, k; for (i=0; isize; i++) { som_idx_to_ndim(som, i, som->b_idx); double dist = 0; for (j=0; jndim; j++) dist += (som->a_idx[j] - som->b_idx[j]) * (som->a_idx[j] - som->b_idx[j]); if ( dist <= radius ) { double influence = exp(-dist*dist*0.5/radius) * learning_rate; for (k=0; kkdim; k++) ptr[k] += influence * (vec[k] - ptr[k]); // Bad sites may help to shape the map, but only nodes with big enough // influence will be used for classification. if ( update_counts ) *cnt += influence; } ptr += som->kdim; cnt++; } } static void som_norm_counts(som_t *som) { int i; double max = 0; for (i=0; isize; i++) if ( max < som->c[i] ) max = som->c[i]; for (i=0; isize; i++) som->c[i] /= max; } static som_t *som_init(args_t *args) { som_t *som = (som_t*) calloc(1,sizeof(som_t)); som->ndim = args->ndim; som->nbin = args->nbin; som->kdim = args->mvals; som->nt = args->ntrain; som->learn = args->learn; som->bmu_th = args->bmu_th; som->size = pow(som->nbin,som->ndim); som->w = (double*) malloc(sizeof(double)*som->size*som->kdim); if ( !som->w ) error("Could not alloc %"PRIu64" bytes [nbin=%d ndim=%d kdim=%d]\n", (uint64_t)(sizeof(double)*som->size*som->kdim),som->nbin,som->ndim,som->kdim); som->c = (double*) calloc(som->size,sizeof(double)); if ( !som->w ) error("Could not alloc %"PRIu64" bytes [nbin=%d ndim=%d]\n", (uint64_t)(sizeof(double)*som->size),som->nbin,som->ndim); int i; for (i=0; isize*som->kdim; i++) som->w[i] = random(); som->a_idx = (int*) malloc(sizeof(int)*som->ndim); som->b_idx = (int*) malloc(sizeof(int)*som->ndim); som->div = (double*) malloc(sizeof(double)*som->ndim); for (i=0; indim; i++) som->div[i] = pow(som->nbin,som->ndim-i-1); return som; } static void som_destroy(som_t *som) { free(som->a_idx); free(som->b_idx); free(som->div); free(som->w); free(som->c); free(som); } static void init_data(args_t *args) { // Get first line to learn the vector size annots_reader_reset(args); annots_reader_next(args); if ( args->action==SOM_CLASSIFY ) args->som = som_load_map(args->prefix,&args->nfold); } static void destroy_data(args_t *args) { int i; if ( args->som ) { for (i=0; infold; i++) som_destroy(args->som[i]); } free(args->train_dat); free(args->train_class); free(args->som); free(args->vals); free(args->str.s); } #define MERGE_MIN 0 #define MERGE_MAX 1 #define MERGE_AVG 2 static double get_min_score(args_t *args, int iskip) { int i; double score, min_score = HUGE_VAL; for (i=0; infold; i++) { if ( i==iskip ) continue; score = som_get_score(args->som[i], args->vals, args->bmu_th); if ( i==0 || score < min_score ) min_score = score; } return min_score; } static double get_max_score(args_t *args, int iskip) { int i; double score, max_score = -HUGE_VAL; for (i=0; infold; i++) { if ( i==iskip ) continue; score = som_get_score(args->som[i], args->vals, args->bmu_th); if ( i==0 || max_score < score ) max_score = score; } return max_score; } static double get_avg_score(args_t *args, int iskip) { int i, n = 0; double score = 0; for (i=0; infold; i++) { if ( i==iskip ) continue; score += som_get_score(args->som[i], args->vals, args->bmu_th); n++; } return score/n; } static int cmpfloat_desc(const void *a, const void *b) { float fa = *((float*)a); float fb = *((float*)b); if ( fafb ) return -1; return 0; } static void create_eval_plot(args_t *args) { FILE *fp = open_file(NULL,"w","%s.eval.py", args->prefix); fprintf(fp, "import matplotlib as mpl\n" "mpl.use('Agg')\n" "import matplotlib.pyplot as plt\n" "\n" "import csv\n" "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" "dat = []\n" "with open('%s.eval', 'r') as f:\n" "\treader = csv.reader(f, 'tab')\n" "\tfor row in reader:\n" "\t\tif row[0][0]!='#': dat.append(row)\n" "\n" "fig = plt.figure()\n" "ax1 = plt.subplot(111)\n" "ax1.plot([x[0] for x in dat],[x[1] for x in dat],'g',label='Good')\n" "ax1.plot([x[0] for x in dat],[x[2] for x in dat],'r',label='Bad')\n" "ax1.set_xlabel('SOM score')\n" "ax1.set_ylabel('Number of training sites')\n" "ax1.legend(loc='best',prop={'size':8},frameon=False)\n" "plt.savefig('%s.eval.png')\n" "plt.close()\n" "\n", args->prefix,args->prefix ); fclose(fp); } static void do_train(args_t *args) { // read training sites int i, igood = 0, ibad = 0, ngood = 0, nbad = 0, ntrain = 0; annots_reader_reset(args); while ( annots_reader_next(args) ) { // determine which of the nfold's SOMs to train int isom = 0; if ( args->dclass == args->good_class ) { if ( ++igood >= args->nfold ) igood = 0; isom = igood; ngood++; } else if ( args->dclass == args->bad_class ) { if ( ++ibad >= args->nfold ) ibad = 0; isom = ibad; nbad++; } else error("Could not determine the class: %d (vs %d and %d)\n", args->dclass,args->good_class,args->bad_class); // save the values for evaluation ntrain++; hts_expand(double, ntrain*args->mvals, args->mtrain_dat, args->train_dat); hts_expand(int, ntrain, args->mtrain_class, args->train_class); memcpy(args->train_dat+(ntrain-1)*args->mvals, args->vals, args->mvals*sizeof(double)); args->train_class[ntrain-1] = (args->dclass==args->good_class ? 1 : 0) | isom<<1; // store class + chunk used for training } annots_reader_close(args); // init maps if ( !args->ntrain ) args->ntrain = ngood/args->nfold; srandom(args->rand_seed); args->som = (som_t**) malloc(sizeof(som_t*)*args->nfold); for (i=0; infold; i++) args->som[i] = som_init(args); // train for (i=0; itrain_class[i] & 1; int isom = args->train_class[i] >> 1; if ( is_good || args->train_bad ) som_train_site(args->som[isom], args->train_dat+i*args->mvals, is_good); } // norm and create plots for (i=0; infold; i++) { som_norm_counts(args->som[i]); if ( args->prefix ) { char *bname = msprintf("%s.som.%d", args->prefix,i); som_create_plot(args->som[i], bname); free(bname); } } // evaluate float *good = (float*) malloc(sizeof(float)*ngood); assert(good); float *bad = (float*) malloc(sizeof(float)*nbad); assert(bad); igood = ibad = 0; double max_score = sqrt(args->som[0]->kdim); for (i=0; itrain_class[i] & 1; int isom = args->train_class[i] >> 1; // this vector was used for training isom-th SOM, skip if ( args->nfold==1 ) isom = -1; memcpy(args->vals, args->train_dat+i*args->mvals, args->mvals*sizeof(double)); switch (args->merge) { case MERGE_MIN: score = get_min_score(args, isom); break; case MERGE_MAX: score = get_max_score(args, isom); break; case MERGE_AVG: score = get_avg_score(args, isom); break; } score = 1.0 - score/max_score; if ( is_good ) good[igood++] = score; else bad[ibad++] = score; } qsort(good, ngood, sizeof(float), cmpfloat_desc); qsort(bad, nbad, sizeof(float), cmpfloat_desc); FILE *fp = NULL; if ( args->prefix ) fp = open_file(NULL,"w","%s.eval", args->prefix); igood = 0; ibad = 0; float prev_score = good[0]>bad[0] ? good[0] : bad[0]; int printed = 0; while ( igood 0.9 ) { printf("%.2f\t%.2f\t%e\t# %% of bad [1] and good [2] sites at a cutoff [3]\n", 100.*ibad/nbad,100.*igood/ngood,prev_score); printed = 1; } if ( igoodbad[ibad] ? good[igood] : bad[ibad]; else if ( igoodprefix,strerror(errno)); create_eval_plot(args); som_write_map(args->prefix, args->som, args->nfold); } free(good); free(bad); } static void do_classify(args_t *args) { annots_reader_reset(args); double max_score = sqrt(args->som[0]->kdim); while ( annots_reader_next(args) ) { double score = 0; switch (args->merge) { case MERGE_MIN: score = get_min_score(args, -1); break; case MERGE_MAX: score = get_max_score(args, -1); break; case MERGE_AVG: score = get_avg_score(args, -1); break; } printf("%e\n", 1.0 - score/max_score); } annots_reader_close(args); } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: SOM (Self-Organizing Map) filtering.\n"); fprintf(stderr, "Usage: bcftools som --train [options] \n"); fprintf(stderr, " bcftools som --classify [options]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Model training options:\n"); fprintf(stderr, " -f, --nfold n-fold cross-validation (number of maps) [5]\n"); fprintf(stderr, " -p, --prefix prefix of output files\n"); fprintf(stderr, " -s, --size map size [20]\n"); fprintf(stderr, " -t, --train \n"); fprintf(stderr, "\n"); fprintf(stderr, "Classifying options:\n"); fprintf(stderr, " -c, --classify \n"); fprintf(stderr, "\n"); fprintf(stderr, "Experimental training options (no reason to change):\n"); fprintf(stderr, " -b, --bmu-threshold threshold for selection of best-matching unit [0.9]\n"); fprintf(stderr, " -d, --som-dimension SOM dimension [2]\n"); fprintf(stderr, " -e, --exclude-bad exclude bad sites from training, use for evaluation only\n"); fprintf(stderr, " -l, --learning-rate learning rate [1.0]\n"); fprintf(stderr, " -m, --merge -f merge algorithm [avg]\n"); fprintf(stderr, " -n, --ntrain-sites effective number of training sites [number of good sites]\n"); fprintf(stderr, " -r, --random-seed random seed, 0 for time() [1]\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfsom(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->nbin = 20; args->learn = 1.0; args->bmu_th = 0.9; args->nfold = 5; args->rand_seed = 1; args->ndim = 2; args->bad_class = 1; args->good_class = 2; args->merge = MERGE_AVG; args->train_bad = 1; static struct option loptions[] = { {"help",0,0,'h'}, {"prefix",1,0,'p'}, {"ntrain-sites",1,0,'n'}, {"random-seed",1,0,'r'}, {"bmu-threshold",1,0,'b'}, {"exclude-bad",0,0,'e'}, {"learning-rate",1,0,'l'}, {"size",1,0,'s'}, {"som-dimension",1,0,'d'}, {"nfold",1,0,'f'}, {"merge",1,0,'m'}, {"train",0,0,'t'}, {"classify",0,0,'c'}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "htcp:n:r:b:l:s:f:d:m:e",loptions,NULL)) >= 0) { switch (c) { case 'e': args->train_bad = 0; break; case 'm': if ( !strcmp(optarg,"min") ) args->merge = MERGE_MIN; else if ( !strcmp(optarg,"max") ) args->merge = MERGE_MAX; else if ( !strcmp(optarg,"avg") ) args->merge = MERGE_AVG; else error("The -m method not recognised: %s\n", optarg); break; case 'p': args->prefix = optarg; break; case 'n': args->ntrain = atoi(optarg); break; case 'r': args->rand_seed = atoi(optarg); break; case 'b': args->bmu_th = atof(optarg); break; case 'l': args->learn = atof(optarg); break; case 's': args->nbin = atoi(optarg); break; case 'f': args->nfold = atoi(optarg); break; case 'd': args->ndim = atoi(optarg); if ( args->ndim<2 ) error("Expected -d >=2, got %d\n", args->ndim); if ( args->ndim>3 ) fprintf(stderr,"Warning: This will take a long time and is not going to make the results better: -d %d\n", args->ndim); break; case 't': args->action = SOM_TRAIN; break; case 'c': args->action = SOM_CLASSIFY; break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } if ( !args->rand_seed ) args->rand_seed = time(NULL); if ( argc!=optind+1 ) usage(); args->fname = argv[optind]; init_data(args); if ( args->action == SOM_TRAIN ) do_train(args); else if ( args->action == SOM_CLASSIFY ) do_classify(args); destroy_data(args); free(args); return 0; } bcftools-1.21/vcfsort.c000066400000000000000000000624611467060157400151250ustar00rootroot00000000000000/* vcfsort.c -- sort subcommand Copyright (C) 2017-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #ifdef _WIN32 #include #endif #include #include #include #include #include #include "kheap.h" #include "bcftools.h" #define MAX_TMP_FILES_PER_LAYER 32 #define MERGE_LAYERS 12 #define MAX_TMP_FILES (MAX_TMP_FILES_PER_LAYER * MERGE_LAYERS) typedef struct { char *fname; htsFile *fh; BGZF *bgz; size_t idx; bcf1_t *rec; int is_merged; } blk_t; typedef struct { size_t len; hts_pos_t pos; int rid; float qual; uint8_t data[]; } packed_bcf_t; typedef struct _args_t { bcf_hdr_t *hdr; char **argv, *fname, *output_fname, *tmp_dir; int argc, output_type, clevel; size_t max_mem, mem; packed_bcf_t **buf; uint8_t *mem_block; size_t nbuf, mbuf, nblk, tmp_count; blk_t blk[MAX_TMP_FILES]; uint32_t tmp_layers[MERGE_LAYERS]; int write_index; } args_t; void clean_files(args_t *args) { int i; fprintf(stderr,"Cleaning\n"); for (i=0; iblk[i]; if ( blk->fname ) { unlink(blk->fname); free(blk->fname); } if ( blk->rec ) bcf_destroy(blk->rec); } rmdir(args->tmp_dir); } void HTS_FORMAT(HTS_PRINTF_FMT, 2, 3) HTS_NORETURN clean_files_and_throw(args_t *args, const char *format, ...) { va_list ap; va_start(ap, format); vfprintf(stderr, format, ap); va_end(ap); clean_files(args); exit(-1); } int cmp_bcf_pos(const void *aptr, const void *bptr) { bcf1_t *a = *((bcf1_t**)aptr); bcf1_t *b = *((bcf1_t**)bptr); if ( a->rid < b->rid ) return -1; if ( a->rid > b->rid ) return 1; if ( a->pos < b->pos ) return -1; if ( a->pos > b->pos ) return 1; return 0; } int cmp_bcf_pos_ref_alt(const void *aptr, const void *bptr) { bcf1_t *a = *((bcf1_t**)aptr); bcf1_t *b = *((bcf1_t**)bptr); if ( a->rid < b->rid ) return -1; if ( a->rid > b->rid ) return 1; if ( a->pos < b->pos ) return -1; if ( a->pos > b->pos ) return 1; // Sort the same chr:pos records lexicographically by ref,alt. // This will be called rarely so should not slow the sorting down // noticeably. int i; for (i=0; in_allele; i++) { if ( i >= b->n_allele ) return 1; int ret = strcasecmp(a->d.allele[i],b->d.allele[i]); if ( ret ) return ret; } if ( a->n_allele < b->n_allele ) return -1; return 0; } static int cmp_packed_bcf_pos_ref_alt(const void *aptr, const void *bptr) { packed_bcf_t *a = *(packed_bcf_t **) aptr; packed_bcf_t *b = *(packed_bcf_t **) bptr; if ( a->rid < b->rid ) return -1; if ( a->rid > b->rid ) return 1; if ( a->pos < b->pos ) return -1; if ( a->pos > b->pos ) return 1; // Sort lexicographically by ref,alt. These are stored tab-separated // as the first item in packed_bcf_t::data return strcmp((char *) a->data, (char *) b->data); } static int cmp_packed_bcf_pos_ref_alt_stable(const void *aptr, const void *bptr) { // cmp_bcf_pos_ref_alt() with tie-breaker to make qsort stable int res = cmp_packed_bcf_pos_ref_alt(aptr, bptr); if (res != 0) return res; // Got a tie - use the position in the original input to break it. // As everything is read into a big memory buffer, for most records // we can just compare the pointers directly. The exception is // any record that didn't quite fit in the memory buffer, causing it to be // flushed. Those are flagged by setting packed_bcf_t::len = SIZE_MAX, and // as they were the last record in the segment, they should always sort // after unflagged records. packed_bcf_t *a = *(packed_bcf_t **) aptr; packed_bcf_t *b = *(packed_bcf_t **) bptr; if (a->len == SIZE_MAX) return 1; if (b->len == SIZE_MAX) return -1; return a < b ? -1 : 1; } static uint8_t *pack_unsigned(uint8_t *data, uint64_t val) { do { *data++ = (val & 0x7f) | ((val > 0x7f) ? 0x80 : 0); val >>= 7; } while (val > 0); return data; } static uint8_t *pack_hts_pos(uint8_t *data, hts_pos_t val) { uint64_t sign = val < 0; uint64_t v = val < 0 ? -(val + 1) : val; v = v << 1 | sign; return pack_unsigned(data, v); } static uint8_t *pack_bcf_data(packed_bcf_t *dest, const bcf1_t *src, int outside_buffer) { uint32_t i; uint8_t *data = dest->data; uint8_t *start = dest->data; dest->pos = src->pos; dest->rid = src->rid; dest->qual = src->qual; // Copy in alleles, for the comparison function for (i = 0; i < src->n_allele; i++) { size_t l = strlen(src->d.allele[i]); if (i > 0) *data++ = '\t'; memcpy(data, src->d.allele[i], l); data += l; } *data++ = '\0'; if (outside_buffer) { dest->len = SIZE_MAX; memcpy(data, &src, sizeof(src)); data += sizeof(src); return data; } data = pack_hts_pos(data, src->rlen); data = pack_unsigned(data, src->n_info); data = pack_unsigned(data, src->n_allele); data = pack_unsigned(data, src->n_fmt); data = pack_unsigned(data, src->n_sample); data = pack_unsigned(data, src->shared.l); data = pack_unsigned(data, src->indiv.l); if (src->shared.l) memcpy(data, src->shared.s, src->shared.l); data += src->shared.l; if (src->indiv.l) memcpy(data, src->indiv.s, src->indiv.l); data += src->indiv.l; dest->len = data - start; return data; } static int write_packed_bcf(BGZF *fp, packed_bcf_t *src) { // Write pos, rid, qual size_t len = src->data - (uint8_t *) &src->pos; if (bgzf_write_small(fp, &src->pos, len) < len) return -1; // Skip the copy of the alleles size_t skip = strlen((char *) src->data) + 1; // Write everything else if (src->len < SIZE_MAX) { // In main memory block len = src->len - skip; if (bgzf_write_small(fp, src->data + skip, len) < len) return -1; } else { // Record didn't fit in the main block. To minimize the // overflow, its packed_bcf_t data will be imcomplete. A pointer to // its bcf1_t struct will have been placed after the allele data // so we can finish the packing job and write it in the same format // the rest of the data bcf1_t *rec; uint8_t tmp[100], *data = tmp; memcpy(&rec, src->data + skip, sizeof(rec)); data = pack_hts_pos(data, rec->rlen); data = pack_unsigned(data, rec->n_info); data = pack_unsigned(data, rec->n_allele); data = pack_unsigned(data, rec->n_fmt); data = pack_unsigned(data, rec->n_sample); data = pack_unsigned(data, rec->shared.l); data = pack_unsigned(data, rec->indiv.l); if (bgzf_write_small(fp, tmp, data - tmp) < data - tmp) return -1; if (rec->shared.l > 0 && bgzf_write_small(fp, rec->shared.s, rec->shared.l) < rec->shared.l) return -1; if (rec->indiv.l > 0 && bgzf_write_small(fp, rec->indiv.s, rec->indiv.l) < rec->indiv.l) return -1; } return 0; } static uint64_t unpack_unsigned(BGZF *fp, int *err) { uint8_t data; uint64_t val = 0; uint32_t i = 0; if (bgzf_read_small(fp, &data, sizeof(data)) <= 0) goto short_read; while (data & 0x80) { val |= (uint64_t)(data & 0x7f) << i; i += 7; if (bgzf_read_small(fp, &data, sizeof(data)) <= 0) goto short_read; } val |= (uint64_t)data << i; return val; short_read: *err = 1; return 0; } static hts_pos_t unpack_hts_pos(BGZF *fp, int *err) { uint64_t v = unpack_unsigned(fp, err); if ((v & 1) == 0) return (hts_pos_t)(v >> 1); else return -(hts_pos_t)(v >> 1) - 1; } static int read_packed_bcf(BGZF *fp, bcf1_t *dest) { int err = 0; packed_bcf_t tmp; size_t len = tmp.data - (uint8_t *) &tmp.pos; bcf_clear(dest); ssize_t got = bgzf_read_small(fp, &tmp.pos, len); if (got == 0) return -1; // EOF if (got < len) return -2; // Error or short read dest->pos = tmp.pos; dest->rid = tmp.rid; dest->qual = tmp.qual; dest->rlen = unpack_hts_pos(fp, &err); dest->n_info = unpack_unsigned(fp, &err); dest->n_allele = unpack_unsigned(fp, &err); dest->n_fmt = unpack_unsigned(fp, &err); dest->n_sample = unpack_unsigned(fp, &err); len = unpack_unsigned(fp, &err); if (ks_resize(&dest->shared, len) != 0) return -2; dest->shared.l = len; len = unpack_unsigned(fp, &err); if (ks_resize(&dest->indiv, len) != 0) return -2; dest->indiv.l = len; err |= bgzf_read_small(fp, dest->shared.s, dest->shared.l) < dest->shared.l; err |= bgzf_read_small(fp, dest->indiv.s, dest->indiv.l) < dest->indiv.l; return err == 0 ? 0 : -2; } void open_tmp_file(args_t *args, blk_t *blk, int is_merged) { kstring_t str = {0,0,0}; int tries = 1000; blk->fh = NULL; blk->bgz = NULL; do { if (ksprintf(ks_clear(&str), "%s/%05zd%s", args->tmp_dir, args->tmp_count++, is_merged ? ".bcf" : "") < 0) { clean_files_and_throw(args, "%s", strerror(errno)); } if (is_merged) blk->fh = hts_open(str.s, "wbx1"); else blk->bgz = bgzf_open(str.s, "wx1"); if ( blk->fh == NULL && blk->bgz == NULL && (errno != EEXIST || --tries <= 0)) { clean_files_and_throw(args, "Cannot write %s: %s\n", str.s, strerror(errno)); } } while (blk->fh == NULL && blk->bgz == NULL); blk->fname = ks_release(&str); blk->idx = args->tmp_count - 1; } void do_partial_merge(args_t *args); void buf_flush(args_t *args, bcf1_t *last_rec) { if ( !args->nbuf ) return; qsort(args->buf, args->nbuf, sizeof(*args->buf), cmp_packed_bcf_pos_ref_alt_stable); if (args->tmp_layers[0] >= MAX_TMP_FILES_PER_LAYER) do_partial_merge(args); assert(args->nblk < MAX_TMP_FILES); blk_t *blk = &args->blk[args->nblk]; blk->is_merged = 0; args->nblk++; args->tmp_layers[0]++; assert(blk->fname == NULL && blk->fh == NULL && blk->bgz == NULL); open_tmp_file(args, blk, 0); int i; for (i=0; inbuf; i++) { if ( write_packed_bcf(blk->bgz, args->buf[i])!=0 ) clean_files_and_throw(args, "[%s] Error: cannot write to %s\n", __func__,blk->fname); } if ( bgzf_close(blk->bgz)!=0 ) clean_files_and_throw(args, "[%s] Error: close failed .. %s\n", __func__,blk->fname); blk->bgz = NULL; args->nbuf = 0; args->mem = 0; } static inline uint8_t *_align_up(uint8_t *ptr) { return (uint8_t*)(((size_t)ptr + 8 - 1) & ~((size_t)(8 - 1))); } #define varint_size(X) ((sizeof(X) * 8 + 7) / 7) // worst case void buf_push(args_t *args, bcf1_t *rec) { size_t delta = sizeof(rec->pos) + sizeof(rec->rid) + sizeof(rec->qual) + varint_size(rec->rlen) + varint_size(2) // n_info + varint_size(2) // n_allele + varint_size(1) // n_fmt + varint_size(3) // n_sample + varint_size(rec->shared.l) + varint_size(rec->indiv.l) + rec->shared.l + rec->indiv.l + rec->unpack_size[1] // Alleles + 8; // the number of _align_up() calls if ( delta > args->max_mem - args->mem ) { packed_bcf_t *tmp = malloc(sizeof(*tmp) + rec->unpack_size[1] * sizeof(bcf1_t *)); if (!tmp) clean_files_and_throw(args, "[%s] Out of memory\n", __func__); pack_bcf_data(tmp, rec, 1); args->nbuf++; hts_expand(bcf1_t*, args->nbuf, args->mbuf, args->buf); args->buf[args->nbuf-1] = tmp; buf_flush(args, rec); free(tmp); bcf_destroy(rec); return; } // make sure nothing has changed in htslib assert( rec->unpacked==BCF_UN_STR && !rec->d.flt && !rec->d.info && !rec->d.fmt && !rec->d.var ); uint8_t *ptr_beg = args->mem_block + args->mem; uint8_t *ptr = _align_up(ptr_beg); packed_bcf_t *packed_rec = (packed_bcf_t *) ptr; ptr = pack_bcf_data(packed_rec, rec, 0); args->nbuf++; hts_expand(bcf1_t*, args->nbuf, args->mbuf, args->buf); args->buf[args->nbuf-1] = packed_rec; delta = ptr - ptr_beg; args->mem += delta; assert( args->mem <= args->max_mem ); bcf_destroy(rec); } void sort_blocks(args_t *args) { htsFile *in = hts_open(args->fname, "r"); if ( !in ) clean_files_and_throw(args, "Could not read %s\n", args->fname); args->hdr = bcf_hdr_read(in); if ( !args->hdr) clean_files_and_throw(args, "Could not read VCF/BCF headers from %s\n", args->fname); while ( 1 ) { bcf1_t *rec = bcf_init(); int ret = bcf_read1(in, args->hdr, rec); if ( ret < -1 ) clean_files_and_throw(args,"Error encountered while parsing the input\n"); if ( ret == -1 ) { bcf_destroy(rec); break; } if ( rec->errcode ) clean_files_and_throw(args,"Error encountered while parsing the input at %s:%"PRIhts_pos"\n",bcf_seqname(args->hdr,rec),rec->pos+1); bcf_unpack(rec, BCF_UN_STR); buf_push(args, rec); } buf_flush(args, NULL); free(args->buf); if ( hts_close(in)!=0 ) clean_files_and_throw(args,"Close failed: %s\n", args->fname); } static inline int blk_is_smaller(blk_t **aptr, blk_t **bptr) { blk_t *a = *aptr; blk_t *b = *bptr; int ret = cmp_bcf_pos_ref_alt(&a->rec, &b->rec); if ( ret < 0 ) return 1; if (ret == 0 && a->idx < b->idx) return 1; return 0; } KHEAP_INIT(blk, blk_t*, blk_is_smaller) void blk_read(args_t *args, khp_blk_t *bhp, bcf_hdr_t *hdr, blk_t *blk) { int ret; if (blk->is_merged) { if ( !blk->fh ) return; ret = bcf_read(blk->fh, hdr, blk->rec); } else { if ( !blk->bgz ) return; ret = read_packed_bcf(blk->bgz, blk->rec); } if ( ret < -1 ) clean_files_and_throw(args, "Error reading %s\n", blk->fname); if ( ret == -1 ) { if (blk->is_merged) { if ( hts_close(blk->fh)!=0 ) clean_files_and_throw(args, "Close failed: %s\n", blk->fname); blk->fh = NULL; return; } else { if ( bgzf_close(blk->bgz) != 0) clean_files_and_throw(args, "Close failed: %s\n", blk->fname); blk->bgz = NULL; return; } } bcf_unpack(blk->rec, BCF_UN_STR); khp_insert(blk, bhp, &blk); } void merge_blocks(args_t *args, htsFile *out, const char *output_fname, int idx_fmt, size_t from) { khp_blk_t *bhp = khp_init(blk); char *index_fn = NULL; size_t i; for (i=from; inblk; i++) { blk_t *blk = &args->blk[i]; if (blk->is_merged) { blk->fh = hts_open(blk->fname, "r"); if ( !blk->fh ) clean_files_and_throw(args, "Could not read %s: %s\n", blk->fname, strerror(errno)); bcf_hdr_t *hdr = bcf_hdr_read(blk->fh); bcf_hdr_destroy(hdr); } else { blk->bgz = bgzf_open(blk->fname, "r"); if (!blk->bgz) clean_files_and_throw(args, "Could not read %s: %s\n", blk->fname, strerror(errno)); } blk_read(args, bhp, args->hdr, blk); } if ( bcf_hdr_write(out, args->hdr)!=0 ) clean_files_and_throw(args, "[%s] Error: cannot write to %s\n", __func__, output_fname); if (idx_fmt) { if ( init_index2(out,args->hdr,output_fname,&index_fn,idx_fmt)<0 ) error("Error: failed to initialise index for %s\n",output_fname); } while ( bhp->ndat ) { blk_t *blk = bhp->dat[0]; if ( bcf_write(out, args->hdr, blk->rec)!=0 ) clean_files_and_throw(args, "[%s] Error: cannot write to %s\n", __func__,args->output_fname); khp_delete(blk, bhp); blk_read(args, bhp, args->hdr, blk); } if ( idx_fmt ) { if ( bcf_idx_save(out)<0 ) { if ( hts_close(out)!=0 ) error("Error: close failed .. %s\n", output_fname); error("Error: cannot write to index %s\n", index_fn); } free(index_fn); } for (i = from; i < args->nblk; i++) { blk_t *blk = &args->blk[i]; if (unlink(blk->fname) != 0) clean_files_and_throw(args, "Couldn't remove temporary file %s\n", blk->fname); free(blk->fname); blk->fname = NULL; } khp_destroy(blk, bhp); } void do_partial_merge(args_t *args) { uint32_t to_layer = 0; size_t to_merge = 0; // Temp. files are arranged in layers of at most MAX_TMP_FILES_PER_LAYER. // When a layer is full, it is merged into the next layer up. Each // layer will therefore contain files with exponentially more records // then the previous one, but will be merged exponentially less frequently. // The result is that the overall complexity will remain O(n*log(n)) // even if we need to do lots of partial merges. while (to_layer < MERGE_LAYERS && args->tmp_layers[to_layer] >= MAX_TMP_FILES_PER_LAYER) { to_merge += args->tmp_layers[to_layer]; args->tmp_layers[to_layer] = 0; to_layer++; } assert(to_merge > 0 && to_merge <= args->nblk); if (to_layer == MERGE_LAYERS) { // Edge case - if we've got here, we've completely used the // temp file allocation, so merge absolutely everything and // leave one file at the highest level. Strictly this breaks // the O(n*log(n)) complexity, but unless MERGE_LAYERS and // MAX_TMP_FILES_PER_LAYER are too small it would take so long // to get here it should never actually happen... assert(to_merge == MAX_TMP_FILES_PER_LAYER * MERGE_LAYERS); to_layer = MERGE_LAYERS - 1; } blk_t tmp = { NULL }; open_tmp_file(args, &tmp, 1); merge_blocks(args, tmp.fh, tmp.fname, 0, args->nblk - to_merge); if (hts_close(tmp.fh) != 0) clean_files_and_throw(args, "Close failed: %s\n", tmp.fname); args->nblk -= to_merge; assert(args->blk[args->nblk].fh == NULL); assert(args->blk[args->nblk].fname == NULL); args->blk[args->nblk].is_merged = 1; args->blk[args->nblk].idx = tmp.idx; args->blk[args->nblk++].fname = tmp.fname; args->tmp_layers[to_layer]++; } void merge_to_output(args_t *args) { char wmode[8] = { 0 }; set_wmode(wmode,args->output_type,args->output_fname,args->clevel); const char *output_fname = args->output_fname ? args->output_fname : "-"; htsFile *out = hts_open(output_fname, wmode); if (!out) clean_files_and_throw(args, "[%s] Error: cannot open %s\n", __func__, output_fname); fprintf(stderr,"Merging %zd temporary files\n", args->nblk); merge_blocks(args, out, output_fname, args->write_index, 0); fprintf(stderr,"Done\n"); if ( hts_close(out)!=0 ) clean_files_and_throw(args, "Close failed: %s\n", output_fname); clean_files(args); } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: Sort VCF/BCF file.\n"); fprintf(stderr, "Usage: bcftools sort [OPTIONS] \n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " -m, --max-mem FLOAT[kMG] maximum memory to use [768M]\n"); // using metric units, 1M=1e6 fprintf(stderr, " -o, --output FILE output file name [stdout]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); #ifdef _WIN32 fprintf(stderr, " -T, --temp-dir DIR temporary files [/bcftools.XXXXXX]\n"); #else fprintf(stderr, " -T, --temp-dir DIR temporary files [/tmp/bcftools.XXXXXX]\n"); #endif fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); exit(1); } size_t parse_mem_string(const char *str) { char *tmp; double mem = strtod(str, &tmp); if ( tmp==str ) error("Could not parse the memory string: \"%s\"\n", str); if ( !strcasecmp("k",tmp) ) mem *= 1000; else if ( !strcasecmp("m",tmp) ) mem *= 1000*1000; else if ( !strcasecmp("g",tmp) ) mem *= 1000*1000*1000; return mem; } static void init(args_t *args) { size_t i; args->max_mem *= 0.9; args->mem_block = malloc(args->max_mem); if ( !args->mem_block ) error("Error: could not allocate %zu bytes of memory, try reducing --max-mem\n",args->max_mem); args->mem = 0; for (i = 0; i < MAX_TMP_FILES; i++) { args->blk[i].fname = NULL; args->blk[i].rec = bcf_init(); if (!args->blk[i].rec) clean_files_and_throw(args,"Couldn't allocate bcf record\n"); } args->tmp_dir = init_tmp_prefix(args->tmp_dir); #ifdef _WIN32 int ret = mkdir(mktemp(args->tmp_dir), 0700); if ( ret ) error("mkdir(%s) failed: %s\n", args->tmp_dir,strerror(errno)); #else char *tmp = mkdtemp(args->tmp_dir); if ( !tmp ) error("mkdtemp(%s) failed: %s\n", args->tmp_dir,strerror(errno)); int ret = chmod(tmp, S_IRUSR|S_IWUSR|S_IXUSR); if ( ret ) error("chmod(%s,S_IRUSR|S_IWUSR|S_IXUSR) failed: %s\n", args->tmp_dir,strerror(errno)); #endif fprintf(stderr,"Writing to %s\n", args->tmp_dir); } static void destroy(args_t *args) { bcf_hdr_destroy(args->hdr); free(args->mem_block); free(args->tmp_dir); free(args); } int main_sort(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->max_mem = 768*1000*1000; args->output_fname = "-"; args->clevel = -1; static struct option loptions[] = { {"max-mem",required_argument,NULL,'m'}, {"temp-dir",required_argument,NULL,'T'}, {"output-type",required_argument,NULL,'O'}, {"output-file",required_argument,NULL,'o'}, {"output",required_argument,NULL,'o'}, {"help",no_argument,NULL,'h'}, {"write-index",optional_argument,NULL,'W'}, {0,0,0,0} }; char *tmp; while ((c = getopt_long(argc, argv, "m:T:O:o:W::h?",loptions,NULL)) >= 0) { switch (c) { case 'm': args->max_mem = parse_mem_string(optarg); break; case 'T': args->tmp_dir = optarg; break; case 'o': args->output_fname = optarg; break; case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case 'h': case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin else usage(args); } else args->fname = argv[optind]; init(args); sort_blocks(args); merge_to_output(args); destroy(args); return 0; } bcftools-1.21/vcfstats.c000066400000000000000000002505411467060157400152720ustar00rootroot00000000000000/* vcfstats.c -- Produces stats which can be plotted using plot-vcfstats. Copyright (C) 2012-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ /* Notes and known issues: - SN ts/tv calculation includes all non-ref alleles listed in ALT while per-sample ts/tv takes the first non-ref allele only, something to consider with many non-ref HETs. */ #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "bin.h" #include "dist.h" // Logic of the filters: include or exclude sites which match the filters? #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define HWE_STATS 1 #define QUAL_STATS 1 #define IRC_STATS 1 #define IRC_RLEN 10 #define NA_STRING "0" typedef struct { char *tag; float min, max; uint64_t *vals_ts, *vals_tv; void *val; int nbins, type, m_val, idx; } user_stats_t; typedef struct { int min, max, step, m_vals; uint64_t *vals; } idist_t; // variant allele frequency (fraction of alt allele in pileup as determined from AD) collected into 0.05 bins typedef struct { int snv[21], indel[21]; } vaf_t; typedef struct { uint64_t n_snps, n_indels, n_mnps, n_others, n_mals, n_snp_mals, n_records, n_noalts; int *af_ts, *af_tv, *af_snps; // first bin of af_* stats are singletons #if HWE_STATS int *af_hwe; #endif #if IRC_STATS int n_repeat[IRC_RLEN][4], n_repeat_na; // number of indels which are repeat-consistent, repeat-inconsistent (dels and ins), and not applicable int *af_repeats[3]; #endif int ts_alt1, tv_alt1; #if QUAL_STATS // Values are rounded to one significant digit and 1 is added (Q*10+1); missing and negative values go in the first bin // Only SNPs that are the 1st alternate allele are counted dist_t *qual_ts, *qual_tv, *qual_indels; #endif int *insertions, *deletions, m_indel; // maximum indel length int in_frame, out_frame, na_frame, in_frame_alt1, out_frame_alt1, na_frame_alt1; int subst[15]; int *smpl_hets, *smpl_homRR, *smpl_homAA, *smpl_ts, *smpl_tv, *smpl_indels, *smpl_ndp, *smpl_sngl; int *smpl_hapRef, *smpl_hapAlt, *smpl_missing; int *smpl_ins_hets, *smpl_del_hets, *smpl_ins_homs, *smpl_del_homs; int *smpl_frm_shifts; // not-applicable, in-frame, out-frame vaf_t vaf, *smpl_vaf; // total (INFO/AD) and per-sample (FMT/VAF) VAF distributions unsigned long int *smpl_dp; idist_t dp, dp_sites; int nusr; user_stats_t *usr; double *dvaf; // distribution of the mean indel-allele frequency by length: -m_indel,-(m_indel-1),...-1,0,1,..,m_indel uint32_t *nvaf; } stats_t; typedef struct { uint64_t gt2gt[5][5]; // number of RR->RR, RR->RA, etc. matches/mismatches; see type2stats /* Pearson's R^2 is used for aggregate R^2 y, yy .. sum of dosage and squared dosage in the query VCF (second file) x, xx .. sum of squared dosage in the truth VCF (first file) n .. number of genotypes */ double y, yy, x, xx, yx, n; } gtcmp_t; typedef struct { char *seq; int pos, cnt, len; } _idc1_t; typedef struct { faidx_t *ref; _idc1_t *dat; int ndat, mdat; } indel_ctx_t; typedef struct { // stats stats_t stats[3]; int *tmp_iaf, ntmp_iaf, m_af, m_qual, naf_hwe, mtmp_frm; uint8_t *tmp_frm; int dp_min, dp_max, dp_step; gtcmp_t *smpl_gts_snps, *smpl_gts_indels; gtcmp_t *af_gts_snps, *af_gts_indels; // first bin of af_* stats are singletons bin_t *af_bins; float *farr; int32_t *iarr; int mfarr, miarr; int nref_tot, nhet_tot, nalt_tot, n_nref, i_nref; // indel context indel_ctx_t *indel_ctx; char *ref_fname; // user stats int nusr; user_stats_t *usr; // other bcf_srs_t *files; bcf_sr_regions_t *exons; char **argv, *exons_fname, *regions_list, *samples_list, *targets_list, *af_bins_list, *af_tag; int argc, verbose_sites, first_allele_only, samples_is_file; int split_by_id, nstats; filter_t *filter[2]; char *filter_str; int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE int n_threads; } args_t; static int type2dosage[6], type2ploidy[6], type2stats[7]; static void idist_init(idist_t *d, int min, int max, int step) { d->min = min; d->max = max; d->step = step; d->m_vals = 4 + (d->max - d->min)/d->step; d->vals = (uint64_t*) calloc(d->m_vals,sizeof(uint64_t)); } static void idist_destroy(idist_t *d) { if ( d->vals ) free(d->vals); } static inline uint64_t *idist(idist_t *d, int val) { if ( val < d->min ) return &d->vals[0]; if ( val > d->max ) return &d->vals[d->m_vals-1]; return &d->vals[1 + (val - d->min) / d->step]; } static inline int idist_i2bin(idist_t *d, int i) { if ( i<=0 ) return d->min; if ( i>= d->m_vals ) return d->max; return i-1+d->min; } #define IC_DBG 0 #if IC_DBG static void _indel_ctx_print1(_idc1_t *idc) { int i; fprintf(stdout, "%d\t", idc->cnt); for (i=0; ilen; i++) fputc(idc->seq[i], stdout); fputc('\n', stdout); } static void _indel_ctx_print(indel_ctx_t *ctx) { int i; for (i=0; indat; i++) _indel_ctx_print1(&ctx->dat[i]); fputc('\n',stdout); } #endif static int _indel_ctx_lookup(indel_ctx_t *ctx, char *seq, int seq_len, int *hit) { // binary search int min = 0, max = ctx->ndat - 1; while ( min<=max ) { int i = (min+max)/2; int cmp = strncmp(seq, ctx->dat[i].seq, seq_len); if ( cmp<0 ) max = i - 1; else if ( cmp>0 ) min = i + 1; else { if ( seq_len==ctx->dat[i].len ) { *hit = 1; return i; } else if ( seq_lendat[i].len ) max = i - 1; else min = i + 1; } } *hit = 0; return max; } static void _indel_ctx_insert(indel_ctx_t *ctx, char *seq, int seq_len, int pos) { int idat, hit, i; idat = _indel_ctx_lookup(ctx, seq, seq_len, &hit); if ( !hit ) { if ( pos>0 ) return; idat++; ctx->ndat++; hts_expand(_idc1_t, ctx->ndat+1, ctx->mdat, ctx->dat); if ( idatndat && ctx->ndat>1 ) memmove(&ctx->dat[idat+1], &ctx->dat[idat], (ctx->ndat - idat - 1)*sizeof(_idc1_t)); ctx->dat[idat].len = seq_len; ctx->dat[idat].cnt = 1; ctx->dat[idat].pos = pos; ctx->dat[idat].seq = (char*) malloc(sizeof(char)*(seq_len+1)); for (i=0; idat[idat].seq[i] = seq[i]; ctx->dat[idat].seq[i] = 0; return; } if ( ctx->dat[idat].pos + seq_len == pos ) { ctx->dat[idat].cnt++; ctx->dat[idat].pos = pos; } } indel_ctx_t *indel_ctx_init(char *fa_ref_fname) { indel_ctx_t *ctx = (indel_ctx_t *) calloc(1,sizeof(indel_ctx_t)); ctx->ref = fai_load(fa_ref_fname); if ( !ctx->ref ) { free(ctx); return NULL; } return ctx; } void indel_ctx_destroy(indel_ctx_t *ctx) { fai_destroy(ctx->ref); if ( ctx->mdat ) free(ctx->dat); free(ctx); } /** * indel_ctx_type() - determine indel context type * @ctx: * @chr: chromosome name * @pos: position of the first @ref base, 1-based * @ref: reference allele * @alt: alternate allele. Only first of multiple comma-separated alleles is * considered * @nrep: number of repeated elements (w) * @nlen: length of a single repeat element (w) * * Returns the INDEL length, negative for deletions, positive for insertions */ int indel_ctx_type(indel_ctx_t *ctx, char *chr, int pos, char *ref, char *alt, int *nrep, int *nlen) { const int win_size = 50; // hard-wired for now const int rep_len = IRC_RLEN; // hard-wired for now int ref_len = strlen(ref); int alt_len = 0; while ( alt[alt_len] && alt[alt_len]!=',' ) alt_len++; int i, fai_ref_len; char *fai_ref = faidx_fetch_seq(ctx->ref, chr, pos-1, pos+win_size, &fai_ref_len); for (i=0; i96 ) fai_ref[i] -= 32; // Sanity check: the reference sequence must match the REF allele for (i=0; indat = 0; for (i=0; indat; i++) { if ( max_cnt < ctx->dat[i].cnt || (max_cnt==ctx->dat[i].cnt && max_len < ctx->dat[i].len) ) { max_cnt = ctx->dat[i].cnt; max_len = ctx->dat[i].len; } free(ctx->dat[i].seq); } free(fai_ref); *nrep = max_cnt; *nlen = max_len; return alt_len - ref_len; } static void add_user_stats(args_t *args, char *str) { args->nusr++; args->usr = (user_stats_t*) realloc(args->usr,sizeof(user_stats_t)*args->nusr); user_stats_t *usr = &args->usr[args->nusr-1]; memset(usr,0,sizeof(*usr)); usr->min = 0; usr->max = 1; usr->nbins = 100; usr->idx = 0; char *tmp = str; while ( *tmp && *tmp!=':' ) tmp++; // Tag with an index or just tag? (e.g. PV4[1] vs DP) if ( tmp > str && tmp[-1]==']' ) { char *ptr = tmp; while ( ptr>str && *ptr!='[' ) ptr--; if ( *ptr=='[' ) { char *ptr2; usr->idx = strtol(ptr+1, &ptr2, 10); if ( ptr+1==ptr2 || ptr2 != tmp-1 ) error("Could not parse the index in \"%s\" (ptr=%s;ptr2=%s(%p),tmp=%s(%p),idx=%d)\n", str,ptr,ptr2,ptr2,tmp,tmp,usr->idx); if ( usr->idx<0 ) error("Error: negative index is not allowed: \"%s\"\n", str); *ptr = 0; } } usr->tag = (char*)calloc(tmp-str+2,sizeof(char)); memcpy(usr->tag,str,tmp-str); if ( *tmp ) { char *ptr = ++tmp; usr->min = strtod(tmp, &ptr); if ( tmp==ptr ) error("Could not parse %s\n", str); tmp = ptr+1; } if ( *tmp ) { char *ptr = tmp; usr->max = strtod(tmp, &ptr); if ( tmp==ptr ) error("Could not parse %s\n", str); tmp = ptr+1; } if ( *tmp ) { char *ptr = tmp; usr->nbins = strtol(tmp, &ptr, 10); if ( tmp==ptr ) error("Could not parse %s\n", str); if ( usr->nbins<=0 ) error("Number of bins does not make sense (%d): %s.\n", usr->nbins, str); } } static void init_user_stats(args_t *args, bcf_hdr_t *hdr, stats_t *stats) { stats->nusr = args->nusr; stats->usr = (user_stats_t*)malloc(sizeof(user_stats_t)*args->nusr); if (args->nusr) memcpy(stats->usr,args->usr,args->nusr*sizeof(user_stats_t)); int i; for (i=0; inusr; i++) { user_stats_t *usr = &stats->usr[i]; usr->vals_ts = (uint64_t*)calloc(usr->nbins,sizeof(uint64_t)); usr->vals_tv = (uint64_t*)calloc(usr->nbins,sizeof(uint64_t)); int id = bcf_hdr_id2int(hdr,BCF_DT_ID,usr->tag); if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,id) ) error("The INFO tag \"%s\" is not defined in the header\n", usr->tag); usr->type = bcf_hdr_id2type(hdr,BCF_HL_INFO,id); if ( usr->type!=BCF_HT_REAL && usr->type!=BCF_HT_INT ) error("The INFO tag \"%s\" is not of Float or Integer type (%d)\n", usr->tag, usr->type); } } static void init_stats(args_t *args) { int i; args->nstats = args->files->nreaders==1 ? 1 : 3; if ( args->split_by_id ) args->nstats = 2; if ( args->filter_str ) { args->filter[0] = filter_init(bcf_sr_get_header(args->files,0), args->filter_str); if ( args->files->nreaders==2 ) args->filter[1] = filter_init(bcf_sr_get_header(args->files,1), args->filter_str); args->files->max_unpack |= filter_max_unpack(args->filter[0]); } // AF corresponds to AC but is more robust to mixtures of haploid and diploid GTs if ( !args->af_bins_list ) { args->m_af = 101; for (i=0; ifiles->nreaders; i++) if ( bcf_hdr_nsamples(args->files->readers[i].header) + 1> args->m_af ) args->m_af = bcf_hdr_nsamples(args->files->readers[i].header) + 1; } else { args->af_bins = bin_init(args->af_bins_list,0,1); // m_af is used also for other af arrays, where the first bin is for // singletons. However, since the last element is unused in af_bins // (n boundaries form n-1 intervals), the m_af count is good for both. args->m_af = bin_get_size(args->af_bins); } bcf_hdr_t *hdr = bcf_sr_get_header(args->files,0); if ( args->af_tag && !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,bcf_hdr_id2int(hdr,BCF_DT_ID,args->af_tag)) ) error("No such INFO tag: %s\n", args->af_tag); int id, has_fmt_ad = ((id=bcf_hdr_id2int(hdr,BCF_DT_ID,"AD"))>=0 && bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,id)) ? 1 : 0; #if QUAL_STATS args->m_qual = 999; #endif #if HWE_STATS args->naf_hwe = 100; #endif if ( args->samples_list ) { if ( !bcf_sr_set_samples(args->files,args->samples_list,args->samples_is_file) ) { if ( !bcf_hdr_nsamples(args->files->readers[0].header) ) error("No sample columns in %s\n", args->files->readers[0].fname); error("Unable to parse the samples: \"%s\"\n", args->samples_list); } args->af_gts_snps = (gtcmp_t *) calloc(args->m_af,sizeof(gtcmp_t)); args->af_gts_indels = (gtcmp_t *) calloc(args->m_af,sizeof(gtcmp_t)); args->smpl_gts_snps = (gtcmp_t *) calloc(args->files->n_smpl,sizeof(gtcmp_t)); args->smpl_gts_indels = (gtcmp_t *) calloc(args->files->n_smpl,sizeof(gtcmp_t)); } for (i=0; instats; i++) { stats_t *stats = &args->stats[i]; stats->m_indel = 60; stats->insertions = (int*) calloc(stats->m_indel,sizeof(int)); stats->deletions = (int*) calloc(stats->m_indel,sizeof(int)); stats->af_ts = (int*) calloc(args->m_af,sizeof(int)); stats->af_tv = (int*) calloc(args->m_af,sizeof(int)); stats->af_snps = (int*) calloc(args->m_af,sizeof(int)); int j; for (j=0; j<3; j++) stats->af_repeats[j] = (int*) calloc(args->m_af,sizeof(int)); #if QUAL_STATS stats->qual_ts = dist_init(5); stats->qual_tv = dist_init(5); stats->qual_indels = dist_init(5); #endif if ( args->files->n_smpl ) { stats->smpl_missing = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_hets = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_homAA = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_homRR = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_hapRef = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_hapAlt = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_ins_hets = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_del_hets = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_ins_homs = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_del_homs = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_ts = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_tv = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_indels = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_dp = (unsigned long int *) calloc(args->files->n_smpl,sizeof(unsigned long int)); stats->smpl_ndp = (int *) calloc(args->files->n_smpl,sizeof(int)); stats->smpl_sngl = (int *) calloc(args->files->n_smpl,sizeof(int)); if ( has_fmt_ad ) stats->smpl_vaf = (vaf_t*) calloc(args->files->n_smpl,sizeof(vaf_t)); #if HWE_STATS stats->af_hwe = (int*) calloc(args->m_af*args->naf_hwe,sizeof(int)); #endif if ( args->exons_fname ) stats->smpl_frm_shifts = (int*) calloc(args->files->n_smpl*3,sizeof(int)); stats->nvaf = (uint32_t*) calloc(stats->m_indel*2+1,sizeof(*stats->nvaf)); stats->dvaf = (double*) calloc(stats->m_indel*2+1,sizeof(*stats->dvaf)); } idist_init(&stats->dp, args->dp_min,args->dp_max,args->dp_step); idist_init(&stats->dp_sites, args->dp_min,args->dp_max,args->dp_step); init_user_stats(args, i!=1 ? args->files->readers[0].header : args->files->readers[1].header, stats); } if ( args->exons_fname ) { args->exons = bcf_sr_regions_init(args->exons_fname,1,0,1,2); if ( !args->exons ) error("Error occurred while reading, was the file compressed with bgzip: %s?\n", args->exons_fname); } #if IRC_STATS if ( args->ref_fname ) args->indel_ctx = indel_ctx_init(args->ref_fname); #endif type2dosage[GT_HOM_RR] = 0; type2dosage[GT_HET_RA] = 1; type2dosage[GT_HOM_AA] = 2; type2dosage[GT_HET_AA] = 2; type2dosage[GT_HAPL_R] = 0; type2dosage[GT_HAPL_A] = 1; type2ploidy[GT_HOM_RR] = 1; type2ploidy[GT_HET_RA] = 1; type2ploidy[GT_HOM_AA] = 1; type2ploidy[GT_HET_AA] = 1; type2ploidy[GT_HAPL_R] = -1; type2ploidy[GT_HAPL_A] = -1; type2stats[GT_HOM_RR] = 0; type2stats[GT_HET_RA] = 1; type2stats[GT_HOM_AA] = 2; type2stats[GT_HET_AA] = 3; type2stats[GT_HAPL_R] = 0; type2stats[GT_HAPL_A] = 2; type2stats[GT_UNKN] = 4; } static void destroy_stats(args_t *args) { int id, j; for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; if (stats->af_ts) free(stats->af_ts); if (stats->af_tv) free(stats->af_tv); if (stats->af_snps) free(stats->af_snps); for (j=0; j<3; j++) if (stats->af_repeats[j]) free(stats->af_repeats[j]); #if QUAL_STATS if (stats->qual_ts) dist_destroy(stats->qual_ts); if (stats->qual_tv) dist_destroy(stats->qual_tv); if (stats->qual_indels) dist_destroy(stats->qual_indels); #endif #if HWE_STATS free(stats->af_hwe); #endif free(stats->insertions); free(stats->deletions); free(stats->smpl_missing); free(stats->smpl_hets); free(stats->smpl_homAA); free(stats->smpl_homRR); free(stats->smpl_hapRef); free(stats->smpl_hapAlt); free(stats->smpl_ins_homs); free(stats->smpl_del_homs); free(stats->smpl_ins_hets); free(stats->smpl_del_hets); free(stats->smpl_ts); free(stats->smpl_tv); free(stats->smpl_indels); free(stats->smpl_dp); free(stats->smpl_ndp); free(stats->smpl_sngl); free(stats->smpl_vaf); idist_destroy(&stats->dp); idist_destroy(&stats->dp_sites); for (j=0; jnusr; j++) { free(stats->usr[j].vals_ts); free(stats->usr[j].vals_tv); free(stats->usr[j].val); } free(stats->usr); if ( args->exons ) free(stats->smpl_frm_shifts); free(stats->nvaf); free(stats->dvaf); } for (j=0; jnusr; j++) free(args->usr[j].tag); if ( args->af_bins ) bin_destroy(args->af_bins); free(args->farr); free(args->iarr); free(args->usr); free(args->tmp_frm); free(args->tmp_iaf); if (args->exons) bcf_sr_regions_destroy(args->exons); free(args->af_gts_snps); free(args->af_gts_indels); free(args->smpl_gts_snps); free(args->smpl_gts_indels); if (args->indel_ctx) indel_ctx_destroy(args->indel_ctx); if (args->filter[0]) filter_destroy(args->filter[0]); if (args->filter[1]) filter_destroy(args->filter[1]); } // The arary tmp_iaf keeps the index of AF bin for each allele, the first bin is for singletons. // The number of bins, either m_af (101) or as given by the user in --af-bins static void init_iaf(args_t *args, bcf_sr_t *reader) { bcf1_t *line = reader->buffer[0]; hts_expand(int32_t,line->n_allele,args->ntmp_iaf,args->tmp_iaf); int i, ret; if ( args->af_tag ) { ret = bcf_get_info_float(reader->header, line, args->af_tag, &args->farr, &args->mfarr); if ( ret<=0 || ret!=line->n_allele-1 ) { // the AF tag is not present or wrong number of values, put in the singletons/unknown bin for (i=0; in_allele; i++) args->tmp_iaf[i] = 0; return; } args->tmp_iaf[0] = 0; for (i=1; in_allele; i++) { float af = args->farr[i-1]; if ( af<0 ) af = 0; else if ( af>1 ) af = 1; int iaf = args->af_bins ? bin_get_idx(args->af_bins,af) : af*(args->m_af-2); args->tmp_iaf[i] = iaf + 1; // the first tmp_iaf bin is reserved for singletons } return; } // tmp_iaf is first filled with AC counts in calc_ac and then transformed to // an index to af_gts_snps ret = bcf_calc_ac(reader->header, line, args->tmp_iaf, args->samples_list ? BCF_UN_INFO|BCF_UN_FMT : BCF_UN_INFO); if ( !ret ) { for (i=0; in_allele; i++) args->tmp_iaf[i] = 0; // singletons/unknown bin return; } int an = 0; for (i=0; in_allele; i++) an += args->tmp_iaf[i]; args->tmp_iaf[0] = 0; for (i=1; in_allele; i++) { if ( args->tmp_iaf[i]==1 ) args->tmp_iaf[i] = 0; // singletons into the first bin else if ( !an ) args->tmp_iaf[i] = 1; // no genotype at all, put to the AF=0 bin else { float af = (float) args->tmp_iaf[i] / an; if ( af<0 ) af = 0; else if ( af>1 ) af = 1; int iaf = args->af_bins ? bin_get_idx(args->af_bins,af) : af*(args->m_af-2); args->tmp_iaf[i] = iaf + 1; } } } static inline void do_mnp_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) { stats->n_mnps++; } static inline void do_other_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) { stats->n_others++; } static void do_indel_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) { stats->n_indels++; bcf1_t *line = reader->buffer[0]; #if QUAL_STATS int iqual = (isnan(line->qual) || line->qual<0) ? 0 : 1 + (int)(line->qual*10); dist_insert(stats->qual_indels, iqual); #endif // Check if the indel is near an exon for the frameshift statistics int i, exon_overlap = 0; if ( args->exons ) { if ( !bcf_sr_regions_overlap(args->exons, bcf_seqname(reader->header,line),line->pos,line->pos) ) exon_overlap = 1; hts_expand(uint8_t,line->n_allele,args->mtmp_frm,args->tmp_frm); for (i=0; in_allele; i++) args->tmp_frm[i] = 0; } for (i=1; in_allele; i++) { if ( args->first_allele_only && i>1 ) break; int is_indel = bcf_has_variant_type(line,i,VCF_INDEL); if (is_indel < 0) error("bcf_has_variant_type() failed."); if ( !is_indel ) continue; int len = bcf_variant_length(line, i); #if IRC_STATS // Indel repeat consistency if ( args->indel_ctx ) { int nrep, nlen, ndel; ndel = indel_ctx_type(args->indel_ctx, (char*)reader->header->id[BCF_DT_CTG][line->rid].key, line->pos+1, line->d.allele[0], line->d.allele[i], &nrep, &nlen); if ( nlen<=1 || nrep<=1 ) { // not a repeat or a single base repeat stats->n_repeat_na++; stats->af_repeats[2][ args->tmp_iaf[i] ]++; } else { if ( abs(ndel) % nlen ) { // the length of the inserted/deleted sequence is not consistent with the repeat element stats->n_repeat[nlen-1][ndel<0 ? 1 : 3]++; stats->af_repeats[1][ args->tmp_iaf[i] ]++; } else { // the length consistent with the repeat stats->n_repeat[nlen-1][ndel<0 ? 0 : 2]++; stats->af_repeats[0][ args->tmp_iaf[i] ]++; } } } else stats->af_repeats[2][ args->tmp_iaf[i] ]++; #endif // Check the frameshifts int tlen = 0; if ( args->exons && exon_overlap ) // there is an exon { if ( len>0 ) { // insertion if ( args->exons->start <= line->pos && args->exons->end > line->pos ) tlen = abs(len); } else if ( args->exons->start <= line->pos + abs(len) ) { // deletion tlen = abs(len); if ( line->pos < args->exons->start ) // trim the beginning tlen -= args->exons->start - line->pos + 1; if ( args->exons->end < line->pos + abs(len) ) // trim the end tlen -= line->pos + abs(len) - args->exons->end; } } if ( tlen ) // there are some deleted/inserted bases in the exon { if ( tlen%3 ) { stats->out_frame++; args->tmp_frm[i] = 2; } else { stats->in_frame++; args->tmp_frm[i] = 1; } if ( i==1 ) { if ( tlen%3 ) stats->out_frame_alt1++; else stats->in_frame_alt1++; } } else // no exon affected { if ( i==1 ) stats->na_frame_alt1++; stats->na_frame++; } // Indel length distribution int *ptr = stats->insertions; if ( len<0 ) { len *= -1; ptr = stats->deletions; } if ( --len >= stats->m_indel ) len = stats->m_indel-1; ptr[len]++; } } static void do_user_stats(stats_t *stats, bcf_sr_t *reader, int is_ts) { int i, nval; for (i=0; inusr; i++) { user_stats_t *usr = &stats->usr[i]; uint64_t *vals = is_ts ? usr->vals_ts : usr->vals_tv; float val; if ( usr->type==BCF_HT_REAL ) { if ( (nval=bcf_get_info_float(reader->header,reader->buffer[0],usr->tag,&usr->val,&usr->m_val))<=0 ) continue; if ( usr->idx >= nval ) continue; val = ((float*)usr->val)[usr->idx]; } else { if ( (nval=bcf_get_info_int32(reader->header,reader->buffer[0],usr->tag,&usr->val,&usr->m_val))<=0 ) continue; if ( usr->idx >= nval ) continue; val = ((int32_t*)usr->val)[usr->idx]; } int idx; if ( val<=usr->min ) idx = 0; else if ( val>=usr->max ) idx = usr->nbins - 1; else idx = (val - usr->min)/(usr->max - usr->min) * (usr->nbins-1); vals[idx]++; } } static void do_snp_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) { stats->n_snps++; bcf1_t *line = reader->buffer[0]; int ref = bcf_acgt2int(*line->d.allele[0]); if ( ref<0 ) return; #if QUAL_STATS int iqual = (isnan(line->qual) || line->qual<0) ? 0 : 1 + (int)(line->qual*10); #endif int i; for (i=1; in_allele; i++) { if ( args->first_allele_only && i>1 ) break; if ( !(bcf_get_variant_type(line,i)&VCF_SNP) ) continue; int alt = bcf_acgt2int(*line->d.allele[i]); if ( alt<0 || ref==alt ) continue; stats->subst[ref<<2|alt]++; int iaf = args->tmp_iaf[i]; stats->af_snps[iaf]++; if ( abs(ref-alt)==2 ) { if (i==1) { stats->ts_alt1++; #if QUAL_STATS dist_insert(stats->qual_ts,iqual); #endif do_user_stats(stats, reader, 1); } stats->af_ts[iaf]++; } else { if (i==1) { stats->tv_alt1++; #if QUAL_STATS dist_insert(stats->qual_tv,iqual); #endif do_user_stats(stats, reader, 0); } stats->af_tv[iaf]++; } } } // Returns the max non-ref AD value static inline int get_ad(bcf1_t *line, bcf_fmt_t *ad_fmt_ptr, int ismpl, int *ial) { int iv, ad = 0; *ial = 0; #define BRANCH_INT(type_t,missing,vector_end) { \ type_t *ptr = (type_t *) (ad_fmt_ptr->p + ad_fmt_ptr->size*ismpl); \ for (iv=1; ivn && ivn_allele; iv++) \ { \ if ( ptr[iv]==vector_end ) break; \ if ( ptr[iv]==missing ) continue; \ if ( ad < ptr[iv] ) { ad = ptr[iv]; *ial = iv; }\ } \ } switch (ad_fmt_ptr->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_missing, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_missing, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_missing, bcf_int32_vector_end); break; default: fprintf(stderr, "[E::%s] todo: %d\n", __func__, ad_fmt_ptr->type); exit(1); break; } #undef BRANCH_INT return ad; } static inline int get_iad(bcf1_t *line, bcf_fmt_t *ad_fmt_ptr, int ismpl, int ial) { #define BRANCH_INT(type_t,missing,vector_end) { \ type_t *ptr = (type_t *) (ad_fmt_ptr->p + ad_fmt_ptr->size*ismpl); \ if ( ptr[ial]==vector_end ) return 0; \ if ( ptr[ial]==missing ) return 0; \ return ptr[ial]; \ } switch (ad_fmt_ptr->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_missing, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_missing, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_missing, bcf_int32_vector_end); break; default: fprintf(stderr, "[E::%s] todo: %d\n", __func__, ad_fmt_ptr->type); exit(1); break; } #undef BRANCH_INT } static inline void update_dvaf(stats_t *stats, bcf1_t *line, int ial, float vaf) { int len = line->d.var[ial].n; if ( len < -stats->m_indel ) len = -stats->m_indel; else if ( len > stats->m_indel ) len = stats->m_indel; int bin = stats->m_indel + len; stats->nvaf[bin]++; stats->dvaf[bin] += vaf; } #define vaf2bin(vaf) ((int)nearbyintf((vaf)/0.05)) static inline void update_vaf(vaf_t *smpl_vaf, bcf1_t *line, int ial, float vaf) { if ( vaf>=0 && vaf<=1 ) { int idx = vaf2bin(vaf); if ( bcf_get_variant_type(line,ial)==VCF_SNP ) smpl_vaf->snv[idx]++; else smpl_vaf->indel[idx]++; } } static inline int calc_sample_depth(args_t *args, int ismpl, bcf_fmt_t *ad_fmt_ptr, bcf_fmt_t *dp_fmt_ptr) { if ( dp_fmt_ptr ) { #define BRANCH_INT(type_t,missing,vector_end) { \ type_t *ptr = (type_t *) (dp_fmt_ptr->p + dp_fmt_ptr->size*ismpl); \ if ( *ptr==missing || *ptr==vector_end ) return -1; \ return *ptr; \ } switch (dp_fmt_ptr->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_missing, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_missing, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_missing, bcf_int32_vector_end); break; default: fprintf(stderr, "[E::%s] todo: %d\n", __func__, dp_fmt_ptr->type); exit(1); break; } #undef BRANCH_INT } if ( ad_fmt_ptr ) { int iv, dp = 0, has_value = 0; #define BRANCH_INT(type_t,missing,vector_end) { \ type_t *ptr = (type_t *) (ad_fmt_ptr->p + ad_fmt_ptr->size*ismpl); \ for (iv=0; ivn; iv++) \ { \ if ( ptr[iv]==vector_end ) break; \ if ( ptr[iv]==missing ) continue; \ has_value = 1; \ dp += ptr[iv]; \ } \ } switch (ad_fmt_ptr->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_missing, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_missing, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_missing, bcf_int32_vector_end); break; default: fprintf(stderr, "[E::%s] todo: %d\n", __func__, ad_fmt_ptr->type); exit(1); break; } #undef BRANCH_INT if ( !has_value ) return -1; return dp; } return -1; } static inline void sample_gt_stats(args_t *args, stats_t *stats, bcf1_t *line, int ismpl, int gt, int ial, int jal) { if ( gt==GT_UNKN ) { stats->smpl_missing[ismpl]++; return; } int var_type = 0; if ( ial>0 ) var_type |= bcf_get_variant_type(line,ial); if ( jal>0 ) var_type |= bcf_get_variant_type(line,jal); if ( gt==GT_HAPL_R || gt==GT_HAPL_A ) { if ( var_type&VCF_INDEL && stats->smpl_frm_shifts ) { assert( ialn_allele ); stats->smpl_frm_shifts[ismpl*3 + args->tmp_frm[ial]]++; } if ( gt == GT_HAPL_R ) stats->smpl_hapRef[ismpl]++; if ( gt == GT_HAPL_A ) stats->smpl_hapAlt[ismpl]++; return; } if ( gt != GT_HOM_RR ) { args->n_nref++; args->i_nref = ismpl; } #if HWE_STATS switch (gt) { case GT_HOM_RR: args->nref_tot++; break; case GT_HET_RA: args->nhet_tot++; break; case GT_HET_AA: case GT_HOM_AA: args->nalt_tot++; break; } #endif if ( var_type&VCF_SNP || var_type==VCF_REF ) // count ALT=. as SNP { if ( gt == GT_HET_RA ) stats->smpl_hets[ismpl]++; else if ( gt == GT_HET_AA ) stats->smpl_hets[ismpl]++; else if ( gt == GT_HOM_RR ) stats->smpl_homRR[ismpl]++; else if ( gt == GT_HOM_AA ) stats->smpl_homAA[ismpl]++; if ( gt != GT_HOM_RR && line->d.var[ial].type&VCF_SNP ) // this is safe, bcf_get_variant_types has been already called { int ref = bcf_acgt2int(*line->d.allele[0]); int alt = bcf_acgt2int(*line->d.allele[ial]); if ( alt<0 ) return; if ( abs(ref-alt)==2 ) stats->smpl_ts[ismpl]++; else stats->smpl_tv[ismpl]++; } if ( gt != GT_HOM_RR && line->d.var[jal].type&VCF_SNP && ial!=jal ) { int ref = bcf_acgt2int(*line->d.allele[0]); int alt = bcf_acgt2int(*line->d.allele[jal]); if ( alt<0 ) return; if ( abs(ref-alt)==2 ) stats->smpl_ts[ismpl]++; else stats->smpl_tv[ismpl]++; } } if ( var_type&VCF_INDEL ) { if ( gt != GT_HOM_RR ) { stats->smpl_indels[ismpl]++; if ( gt==GT_HET_RA || gt==GT_HET_AA ) { int is_ins = 0, is_del = 0; if ( bcf_get_variant_type(line,ial)&VCF_INDEL ) { if ( line->d.var[ial].n < 0 ) is_del = 1; else is_ins = 1; } if ( bcf_get_variant_type(line,jal)&VCF_INDEL ) { if ( line->d.var[jal].n < 0 ) is_del = 1; else is_ins = 1; } // Note that alt-het genotypes with both ins and del allele are counted twice!! if ( is_del ) stats->smpl_del_hets[ismpl]++; if ( is_ins ) stats->smpl_ins_hets[ismpl]++; } else if ( gt==GT_HOM_AA ) { if ( line->d.var[ial].n < 0 ) stats->smpl_del_homs[ismpl]++; else stats->smpl_ins_homs[ismpl]++; } } if ( stats->smpl_frm_shifts ) { assert( ialn_allele && jaln_allele ); stats->smpl_frm_shifts[ismpl*3 + args->tmp_frm[ial]]++; stats->smpl_frm_shifts[ismpl*3 + args->tmp_frm[jal]]++; } } } static void do_sample_stats(args_t *args, stats_t *stats, bcf_sr_t *reader, int matched) { bcf_srs_t *files = args->files; bcf1_t *line = reader->buffer[0]; args->nref_tot = 0; args->nhet_tot = 0; args->nalt_tot = 0; args->n_nref = 0; args->i_nref = 0; bcf_fmt_t *gt_fmt_ptr = bcf_get_fmt(reader->header,reader->buffer[0],"GT"); bcf_fmt_t *ad_fmt_ptr = bcf_get_fmt(reader->header,reader->buffer[0],"AD"); bcf_fmt_t *dp_fmt_ptr = bcf_get_fmt(reader->header,reader->buffer[0],"DP"); int is; for (is=0; isfiles->n_smpl; is++) { // Determine depth int dp = calc_sample_depth(args,is,ad_fmt_ptr,dp_fmt_ptr); if ( dp>0 ) { (*idist(&stats->dp, dp))++; stats->smpl_ndp[is]++; stats->smpl_dp[is] += dp; } // Determine genotype int ial, jal, gt=GT_UNKN; if ( gt_fmt_ptr ) { gt = bcf_gt_type(gt_fmt_ptr, reader->samples[is], &ial, &jal); sample_gt_stats(args,stats,line,is,gt,ial,jal); } // Determine variant allele frequency if ( dp>0 && ad_fmt_ptr ) { float iad = 0, jad = 0; if ( gt==GT_UNKN ) // GT not available { iad = get_ad(line,ad_fmt_ptr,is,&ial); } else if ( gt!=GT_UNKN ) { iad = ial==0 ? 0 : get_iad(line,ad_fmt_ptr,is,ial); jad = jal==0 ? 0 : get_iad(line,ad_fmt_ptr,is,jal); } if ( iad ) { update_dvaf(stats,line,ial,(float)iad/dp); update_vaf(&stats->smpl_vaf[is],line,ial,(float)iad/dp); } if ( jad && iad!=jad ) { update_dvaf(stats,line,jal,(float)jad/dp); update_vaf(&stats->smpl_vaf[is],line,jal,(float)jad/dp); } } } if ( args->n_nref==1 ) stats->smpl_sngl[args->i_nref]++; #if HWE_STATS if ( gt_fmt_ptr && line->n_allele > 1 && (args->nref_tot || args->nhet_tot || args->nalt_tot) ) { // Number of heterozygous genotypes observed for any given allele frequency. This is used // by plot-vcfstats to show the observed vs expected number of hets. There the expected number // of hets is calculated from the probability P(het) = 2*AF*(1-AF). // The array af_hwe is organized as follows // m_af .. number of allele frequency bins // naf_hwe .. the number of het genotype frequency bins // iallele_freq*naf_hwe + ihet_freq // float het_frac = (float)args->nhet_tot / (args->nref_tot + args->nhet_tot + args->nalt_tot); int ihet_freq = het_frac * (args->naf_hwe - 1); int idx = ihet_freq + args->tmp_iaf[1] * args->naf_hwe; stats->af_hwe[idx]++; } #endif if ( matched==3 ) { int is; bcf_fmt_t *fmt0, *fmt1; fmt0 = bcf_get_fmt(files->readers[0].header,files->readers[0].buffer[0],"GT"); if ( !fmt0 ) return; fmt1 = bcf_get_fmt(files->readers[1].header,files->readers[1].buffer[0],"GT"); if ( !fmt1 ) return; // only the first ALT allele is considered if (args->ntmp_iaf <= 1) return; // Do not consider invariate sites int iaf = args->tmp_iaf[1]; int line_type = bcf_get_variant_types(files->readers[0].buffer[0]); gtcmp_t *af_stats = line_type&VCF_SNP ? args->af_gts_snps : args->af_gts_indels; gtcmp_t *smpl_stats = line_type&VCF_SNP ? args->smpl_gts_snps : args->smpl_gts_indels; for (is=0; isn_smpl; is++) { // Simplified comparison: only 0/0, 0/1, 1/1 is looked at as the identity of // actual alleles can be enforced by running without the -c option. int gt0 = bcf_gt_type(fmt0, files->readers[0].samples[is], NULL, NULL); int gt1 = bcf_gt_type(fmt1, files->readers[1].samples[is], NULL, NULL); int idx0 = type2stats[gt0]; int idx1 = type2stats[gt1]; af_stats[iaf].gt2gt[idx0][idx1]++; smpl_stats[is].gt2gt[idx0][idx1]++; if ( gt0 == GT_UNKN || gt1 == GT_UNKN ) continue; if ( type2ploidy[gt0]*type2ploidy[gt1] == -1 ) continue; // cannot compare diploid and haploid genotypes float y = type2dosage[gt0]; float x = type2dosage[gt1]; smpl_stats[is].yx += y*x; smpl_stats[is].x += x; smpl_stats[is].xx += x*x; smpl_stats[is].y += y; smpl_stats[is].yy += y*y; smpl_stats[is].n += 1; af_stats[iaf].yx += y*x; af_stats[iaf].x += x; af_stats[iaf].xx += x*x; af_stats[iaf].y += y; af_stats[iaf].yy += y*y; af_stats[iaf].n += 1; } if ( args->verbose_sites ) { int nm = 0, nmm = 0, nrefm = 0; for (is=0; isn_smpl; is++) { int gt = bcf_gt_type(fmt0, files->readers[0].samples[is], NULL, NULL); if ( gt == GT_UNKN ) continue; int gt2 = bcf_gt_type(fmt1, files->readers[1].samples[is], NULL, NULL); if ( gt2 == GT_UNKN ) continue; if ( gt != gt2 ) { nmm++; bcf_sr_t *reader = &files->readers[0]; printf("DBG\t%s\t%"PRId64"\t%s\t%d\t%d\n",reader->header->id[BCF_DT_CTG][reader->buffer[0]->rid].key,(int64_t) reader->buffer[0]->pos+1,files->samples[is],gt,gt2); } else { if ( gt!=GT_HOM_RR ) nrefm++; nm++; } } float nrd = nrefm+nmm ? 100.*nmm/(nrefm+nmm) : 0; printf("PSD\t%s\t%"PRId64"\t%d\t%d\t%f\n", reader->header->id[BCF_DT_CTG][reader->buffer[0]->rid].key,(int64_t) reader->buffer[0]->pos+1,nm,nmm,nrd); } } } static void do_vcf_stats(args_t *args) { bcf_srs_t *files = args->files; assert( sizeof(int)>files->nreaders ); while ( bcf_sr_next_line(files) ) { bcf_sr_t *reader = NULL; bcf1_t *line = NULL; int ret = 0, i, pass = 1; for (i=0; inreaders; i++) { if ( !bcf_sr_has_line(files,i) ) continue; if ( args->filter[i] ) { int is_ok = filter_test(args->filter[i], bcf_sr_get_line(files,i), NULL); if ( args->filter_logic & FLT_EXCLUDE ) is_ok = is_ok ? 0 : 1; if ( !is_ok ) { pass = 0; break; } } ret |= 1<readers[i]; line = bcf_sr_get_line(files,i); } } if ( !pass ) continue; int line_type = bcf_get_variant_types(line); init_iaf(args, reader); stats_t *stats = &args->stats[ret-1]; if ( args->split_by_id && line->d.id[0]=='.' && !line->d.id[1] ) stats = &args->stats[1]; stats->n_records++; if ( line_type==VCF_REF ) stats->n_noalts++; if ( line_type&VCF_SNP ) do_snp_stats(args, stats, reader); if ( line_type&VCF_INDEL ) do_indel_stats(args, stats, reader); if ( line_type&VCF_MNP ) do_mnp_stats(args, stats, reader); if ( line_type&VCF_OTHER ) do_other_stats(args, stats, reader); if ( line->n_allele>2 ) { stats->n_mals++; if ( line_type == VCF_SNP ) stats->n_snp_mals++; // note: this will be fooled by C>C,T } if ( files->n_smpl ) do_sample_stats(args, stats, reader, ret); if ( bcf_get_info_int32(reader->header,line,"DP",&args->iarr,&args->miarr)==1 ) (*idist(&stats->dp_sites, args->iarr[0]))++; } } static void print_header(args_t *args) { int i; printf("# This file was produced by bcftools stats (%s+htslib-%s) and can be plotted using plot-vcfstats.\n", bcftools_version(),hts_version()); printf("# The command line was:\tbcftools %s ", args->argv[0]); for (i=1; iargc; i++) printf(" %s",args->argv[i]); printf("\n#\n"); printf("# Definition of sets:\n# ID\t[2]id\t[3]tab-separated file names\n"); if ( args->files->nreaders==1 ) { const char *fname = strcmp("-",args->files->readers[0].fname) ? args->files->readers[0].fname : ""; if ( args->split_by_id ) { printf("ID\t0\t%s:known (sites with ID different from \".\")\n", fname); printf("ID\t1\t%s:novel (sites where ID column is \".\")\n", fname); } else printf("ID\t0\t%s\n", fname); } else { const char *fname0 = strcmp("-",args->files->readers[0].fname) ? args->files->readers[0].fname : ""; const char *fname1 = strcmp("-",args->files->readers[1].fname) ? args->files->readers[1].fname : ""; printf("ID\t0\t%s\n", fname0); printf("ID\t1\t%s\n", fname1); printf("ID\t2\t%s\t%s\n", fname0,fname1); if ( args->verbose_sites ) { printf( "# Verbose per-site discordance output.\n" "# PSD\t[2]CHROM\t[3]POS\t[4]Number of matches\t[5]Number of mismatches\t[6]NRD\n"); printf( "# Verbose per-site and per-sample output. Genotype codes: %d:HomRefRef, %d:HomAltAlt, %d:HetAltRef, %d:HetAltAlt, %d:haploidRef, %d:haploidAlt\n" "# DBG\t[2]CHROM\t[3]POS\t[4]Sample\t[5]GT in %s\t[6]GT in %s\n", GT_HOM_RR, GT_HOM_AA, GT_HET_RA, GT_HET_AA, GT_HAPL_R, GT_HAPL_A, fname0,fname1); } } } #define T2S(x) type2stats[x] static void print_stats(args_t *args) { int i, j,k, id; printf("# SN, Summary numbers:\n"); printf("# number of records .. number of data rows in the VCF\n"); printf("# number of no-ALTs .. reference-only sites, ALT is either \".\" or identical to REF\n"); printf("# number of SNPs .. number of rows with a SNP\n"); printf("# number of MNPs .. number of rows with a MNP, such as CC>TT\n"); printf("# number of indels .. number of rows with an indel\n"); printf("# number of others .. number of rows with other type, for example a symbolic allele or\n"); printf("# a complex substitution, such as ACT>TCGA\n"); printf("# number of multiallelic sites .. number of rows with multiple alternate alleles\n"); printf("# number of multiallelic SNP sites .. number of rows with multiple alternate alleles, all SNPs\n"); printf("# \n"); printf("# Note that rows containing multiple types will be counted multiple times, in each\n"); printf("# counter. For example, a row with a SNP and an indel increments both the SNP and\n"); printf("# the indel counter.\n"); printf("# \n"); printf("# SN\t[2]id\t[3]key\t[4]value\n"); for (id=0; idfiles->nreaders; id++) printf("SN\t%d\tnumber of samples:\t%d\n", id, bcf_hdr_nsamples(args->files->readers[id].header)); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; printf("SN\t%d\tnumber of records:\t%"PRIu64"\n", id, stats->n_records); printf("SN\t%d\tnumber of no-ALTs:\t%"PRIu64"\n", id, stats->n_noalts); printf("SN\t%d\tnumber of SNPs:\t%"PRIu64"\n", id, stats->n_snps); printf("SN\t%d\tnumber of MNPs:\t%"PRIu64"\n", id, stats->n_mnps); printf("SN\t%d\tnumber of indels:\t%"PRIu64"\n", id, stats->n_indels); printf("SN\t%d\tnumber of others:\t%"PRIu64"\n", id, stats->n_others); printf("SN\t%d\tnumber of multiallelic sites:\t%"PRIu64"\n", id, stats->n_mals); printf("SN\t%d\tnumber of multiallelic SNP sites:\t%"PRIu64"\n", id, stats->n_snp_mals); } printf("# TSTV, transitions/transversions\n" "# - transitions, see https://en.wikipedia.org/wiki/Transition_(genetics)\n" "# - transversions, see https://en.wikipedia.org/wiki/Transversion\n"); printf("# TSTV\t[2]id\t[3]ts\t[4]tv\t[5]ts/tv\t[6]ts (1st ALT)\t[7]tv (1st ALT)\t[8]ts/tv (1st ALT)\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; int ts=0,tv=0; for (i=0; im_af; i++) { ts += stats->af_ts[i]; tv += stats->af_tv[i]; } printf("TSTV\t%d\t%d\t%d\t%.2f\t%d\t%d\t%.2f\n", id,ts,tv,tv?(float)ts/tv:0, stats->ts_alt1,stats->tv_alt1,stats->tv_alt1?(float)stats->ts_alt1/stats->tv_alt1:0); } if ( args->exons_fname ) { printf("# FS, Indel frameshifts:\n# FS\t[2]id\t[3]in-frame\t[4]out-frame\t[5]not applicable\t[6]out/(in+out) ratio\t[7]in-frame (1st ALT)\t[8]out-frame (1st ALT)\t[9]not applicable (1st ALT)\t[10]out/(in+out) ratio (1st ALT)\n"); for (id=0; idnstats; id++) { int in=args->stats[id].in_frame, out=args->stats[id].out_frame, na=args->stats[id].na_frame; int in1=args->stats[id].in_frame_alt1, out1=args->stats[id].out_frame_alt1, na1=args->stats[id].na_frame_alt1; printf("FS\t%d\t%d\t%d\t%d\t%.2f\t%d\t%d\t%d\t%.2f\n", id, in,out,na,out?(float)out/(in+out):0,in1,out1,na1,out1?(float)out1/(in1+out1):0); } } if ( args->indel_ctx ) { printf("# ICS, Indel context:\n" "# - repeat-consistent, inconsistent and n/a: experimental and useless stats [DEPRECATED]\n"); printf("# ICS\t[2]id\t[3]repeat-consistent\t[4]repeat-inconsistent\t[5]not applicable\t[6]c/(c+i) ratio\n"); for (id=0; idnstats; id++) { int nc = 0, ni = 0, na = args->stats[id].n_repeat_na; for (i=0; istats[id].n_repeat[i][0] + args->stats[id].n_repeat[i][2]; ni += args->stats[id].n_repeat[i][1] + args->stats[id].n_repeat[i][3]; } printf("ICS\t%d\t%d\t%d\t%d\t%.4f\n", id, nc,ni,na,nc+ni ? (float)nc/(nc+ni) : 0.0); } printf("# ICL, Indel context by length:\n" "# - repeat-consistent, inconsistent and n/a: experimental and useless stats [DEPRECATED]\n"); printf("# ICL\t[2]id\t[3]length of repeat element\t[4]repeat-consistent deletions)\t[5]repeat-inconsistent deletions\t[6]consistent insertions\t[7]inconsistent insertions\t[8]c/(c+i) ratio\n"); for (id=0; idnstats; id++) { for (i=1; istats[id].n_repeat[i][0]+args->stats[id].n_repeat[i][2], ni = args->stats[id].n_repeat[i][1]+args->stats[id].n_repeat[i][3]; printf("ICL\t%d\t%d\t%d\t%d\t%d\t%d\t%.4f\n", id, i+1, args->stats[id].n_repeat[i][0],args->stats[id].n_repeat[i][1],args->stats[id].n_repeat[i][2],args->stats[id].n_repeat[i][3], nc+ni ? (float)nc/(nc+ni) : 0.0); } } } printf("# SiS, Singleton stats:\n" "# - allele count, i.e. the number of singleton genotypes (AC=1)\n" "# - number of transitions, see above\n" "# - number of transversions, see above\n" "# - repeat-consistent, inconsistent and n/a: experimental and useless stats [DEPRECATED]\n"); printf("# SiS\t[2]id\t[3]allele count\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; printf("SiS\t%d\t%d\t%d\t%d\t%d\t%d\t%d\t%d\t%d\n", id,1,stats->af_snps[0],stats->af_ts[0],stats->af_tv[0], stats->af_repeats[0][0]+stats->af_repeats[1][0]+stats->af_repeats[2][0],stats->af_repeats[0][0],stats->af_repeats[1][0],stats->af_repeats[2][0]); // put the singletons stats into the first AF bin, note that not all of the stats is transferred (i.e. nrd mismatches) stats->af_snps[1] += stats->af_snps[0]; stats->af_ts[1] += stats->af_ts[0]; stats->af_tv[1] += stats->af_tv[0]; stats->af_repeats[0][1] += stats->af_repeats[0][0]; stats->af_repeats[1][1] += stats->af_repeats[1][0]; stats->af_repeats[2][1] += stats->af_repeats[2][0]; } // move the singletons stats into the first AF bin, singleton stats was collected separately because of init_iaf if ( args->af_gts_snps ) { args->af_gts_snps[1].y += args->af_gts_snps[0].y; args->af_gts_snps[1].yy += args->af_gts_snps[0].yy; args->af_gts_snps[1].xx += args->af_gts_snps[0].xx; args->af_gts_snps[1].yx += args->af_gts_snps[0].yx; args->af_gts_snps[1].n += args->af_gts_snps[0].n; } if ( args->af_gts_indels ) { args->af_gts_indels[1].y += args->af_gts_indels[0].y; args->af_gts_indels[1].yy += args->af_gts_indels[0].yy; args->af_gts_indels[1].xx += args->af_gts_indels[0].xx; args->af_gts_indels[1].yx += args->af_gts_indels[0].yx; args->af_gts_indels[1].n += args->af_gts_indels[0].n; } printf("# AF, Stats by non-reference allele frequency:\n# AF\t[2]id\t[3]allele frequency\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; for (i=1; im_af; i++) // note that af[1] now contains also af[0], see SiS stats output above { if ( stats->af_snps[i]+stats->af_ts[i]+stats->af_tv[i]+stats->af_repeats[0][i]+stats->af_repeats[1][i]+stats->af_repeats[2][i] == 0 ) continue; double af = args->af_bins ? (bin_get_value(args->af_bins,i)+bin_get_value(args->af_bins,i-1))*0.5 : (double)(i-1)/(args->m_af-1); printf("AF\t%d\t%f\t%d\t%d\t%d\t%d\t%d\t%d\t%d\n", id,af,stats->af_snps[i],stats->af_ts[i],stats->af_tv[i], stats->af_repeats[0][i]+stats->af_repeats[1][i]+stats->af_repeats[2][i],stats->af_repeats[0][i],stats->af_repeats[1][i],stats->af_repeats[2][i]); } } #if QUAL_STATS printf("# QUAL, Stats by quality\n# QUAL\t[2]id\t[3]Quality\t[4]number of SNPs\t[5]number of transitions (1st ALT)\t[6]number of transversions (1st ALT)\t[7]number of indels\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; int ndist_ts = dist_nbins(stats->qual_ts); int ndist_tv = dist_nbins(stats->qual_tv); int ndist_in = dist_nbins(stats->qual_indels); int ndist_max = ndist_ts; if ( ndist_max < ndist_tv ) ndist_max = ndist_tv; if ( ndist_max < ndist_in ) ndist_max = ndist_in; uint32_t beg, end; uint32_t nts, ntv, nin; for (i=0; iqual_ts, i, &beg, &end); qval = beg>0 ? 0.1*(beg - 1) : -1; } if ( i < ndist_tv ) { ntv = dist_get(stats->qual_tv, i, &beg, &end); if ( qval==-1 ) qval = beg > 0 ? 0.1*(beg - 1) : -1; } if ( i < ndist_in ) { nin = dist_get(stats->qual_indels, i, &beg, &end); if ( qval==-1 ) qval = beg > 0 ? 0.1*(beg - 1) : -1; } if ( nts+ntv+nin==0 ) continue; printf("QUAL\t%d\t",id); if ( qval==-1 ) printf("."); else printf("%.1f",qval); printf("\t%d\t%d\t%d\t%d\n",nts+ntv,nts,ntv,nin); } } #endif for (i=0; inusr; i++) { printf("# USR:%s/%d\t[2]id\t[3]%s/%d\t[4]number of SNPs\t[5]number of transitions (1st ALT)\t[6]number of transversions (1st ALT)\n", args->usr[i].tag,args->usr[i].idx,args->usr[i].tag,args->usr[i].idx); for (id=0; idnstats; id++) { user_stats_t *usr = &args->stats[id].usr[i]; int j; for (j=0; jnbins; j++) { if ( usr->vals_ts[j]+usr->vals_tv[j] == 0 ) continue; // skip empty bins float val = usr->min + (usr->max - usr->min)*j/(usr->nbins-1); const char * const fmt = usr->type==BCF_HT_REAL ? "USR:%s/%d\t%d\t%e\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"\n" : "USR:%s/%d\t%d\t%.0f\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"\n"; printf(fmt,usr->tag,usr->idx,id,val,usr->vals_ts[j]+usr->vals_tv[j],usr->vals_ts[j],usr->vals_tv[j]); } } } printf("# IDD, InDel distribution:\n# IDD\t[2]id\t[3]length (deletions negative)\t[4]number of sites\t[5]number of genotypes\t[6]mean VAF\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; for (i=stats->m_indel-1; i>=0; i--) { if ( !stats->deletions[i] ) continue; // whops, differently organized arrow, dels are together with ins int bin = stats->m_indel - i - 1; printf("IDD\t%d\t%d\t%d\t", id,-i-1,stats->deletions[i]); if ( stats->nvaf && stats->nvaf[bin] ) printf("%u\t%.2f",stats->nvaf[bin],stats->dvaf[bin]/stats->nvaf[bin]); else printf("0\t."); printf("\n"); } for (i=0; im_indel; i++) { if ( !stats->insertions[i] ) continue; int bin = stats->m_indel + i + 1; printf("IDD\t%d\t%d\t%d\t", id,i+1,stats->insertions[i]); if ( stats->nvaf && stats->nvaf[bin] ) printf("%u\t%.2f",stats->nvaf[bin],stats->dvaf[bin]/stats->nvaf[bin]); else printf("0\t."); printf("\n"); } } printf("# ST, Substitution types:\n# ST\t[2]id\t[3]type\t[4]count\n"); for (id=0; idnstats; id++) { int t; for (t=0; t<15; t++) { if ( t>>2 == (t&3) ) continue; printf("ST\t%d\t%c>%c\t%d\n", id, bcf_int2acgt(t>>2),bcf_int2acgt(t&3),args->stats[id].subst[t]); } } if ( args->files->nreaders>1 && args->files->n_smpl ) { printf("SN\t%d\tnumber of samples:\t%d\n", 2, args->files->n_smpl); int x; for (x=0; x<2; x++) // x=0: snps, x=1: indels { gtcmp_t *stats; if ( x==0 ) { printf("# GCsAF, Genotype concordance by non-reference allele frequency (SNPs)\n# GCsAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes\n"); stats = args->af_gts_snps; } else { printf("# GCiAF, Genotype concordance by non-reference allele frequency (indels)\n# GCiAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes\n"); stats = args->af_gts_indels; } uint64_t nrd_m[4] = {0,0,0,0}, nrd_mm[4] = {0,0,0,0}; // across all bins for (i=0; im_af; i++) { int n = 0; uint64_t m[4] = {0,0,0,0}, mm[4] = {0,0,0,0}; // in i-th AF bin for (j=0; j<4; j++) // rr, ra, aa hom, aa het, ./. for (k=0; k<4; k++) { n += stats[i].gt2gt[j][k]; if ( j==k ) { nrd_m[j] += stats[i].gt2gt[j][k]; m[j] += stats[i].gt2gt[j][k]; } else { nrd_mm[j] += stats[i].gt2gt[j][k]; mm[j] += stats[i].gt2gt[j][k]; } } if ( !i || !n ) continue; // skip singleton stats and empty bins // Pearson's r2 double r2 = 0; if ( stats[i].n ) { r2 = (stats[i].yx - stats[i].x*stats[i].y/stats[i].n); r2 /= sqrt((stats[i].xx - stats[i].x*stats[i].x/stats[i].n) * (stats[i].yy - stats[i].y*stats[i].y/stats[i].n)); r2 *= r2; } double af = args->af_bins ? (bin_get_value(args->af_bins,i)+bin_get_value(args->af_bins,i-1))*0.5 : (double)(i-1)/(args->m_af-1); printf("GC%cAF\t2\t%f", x==0 ? 's' : 'i', af); printf("\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"", m[T2S(GT_HOM_RR)],m[T2S(GT_HET_RA)],m[T2S(GT_HOM_AA)]); printf("\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"", mm[T2S(GT_HOM_RR)],mm[T2S(GT_HET_RA)],mm[T2S(GT_HOM_AA)]); if ( stats[i].n && !isnan(r2) ) printf("\t%f", r2); else printf("\t"NA_STRING); printf("\t%.0f\n", stats[i].n); } if ( x==0 ) { printf("# NRD and discordance is calculated as follows:\n"); printf("# m .. number of matches\n"); printf("# x .. number of mismatches\n"); printf("# NRD = 100 * (xRR + xRA + xAA) / (xRR + xRA + xAA + mRA + mAA)\n"); printf("# RR discordance = 100 * xRR / (xRR + mRR)\n"); printf("# RA discordance = 100 * xRA / (xRA + mRA)\n"); printf("# AA discordance = 100 * xAA / (xAA + mAA)\n"); printf("# Non-Reference Discordance (NRD), SNPs\n# NRDs\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance\n"); } else printf("# Non-Reference Discordance (NRD), indels\n# NRDi\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance\n"); uint64_t m = nrd_m[T2S(GT_HET_RA)] + nrd_m[T2S(GT_HOM_AA)] + nrd_m[T2S(GT_HET_AA)]; uint64_t mm = nrd_mm[T2S(GT_HOM_RR)] + nrd_mm[T2S(GT_HET_RA)] + nrd_mm[T2S(GT_HOM_AA)] + nrd_mm[T2S(GT_HET_AA)]; printf("NRD%c\t2\t%f\t%f\t%f\t%f\n", x==0 ? 's' : 'i', m+mm ? mm*100.0/(m+mm) : 0, nrd_m[T2S(GT_HOM_RR)]+nrd_mm[T2S(GT_HOM_RR)] ? nrd_mm[T2S(GT_HOM_RR)]*100.0/(nrd_m[T2S(GT_HOM_RR)]+nrd_mm[T2S(GT_HOM_RR)]) : 0, nrd_m[T2S(GT_HET_RA)]+nrd_mm[T2S(GT_HET_RA)] ? nrd_mm[T2S(GT_HET_RA)]*100.0/(nrd_m[T2S(GT_HET_RA)]+nrd_mm[T2S(GT_HET_RA)]) : 0, nrd_m[T2S(GT_HOM_AA)]+nrd_mm[T2S(GT_HOM_AA)] ? nrd_mm[T2S(GT_HOM_AA)]*100.0/(nrd_m[T2S(GT_HOM_AA)]+nrd_mm[T2S(GT_HOM_AA)]) : 0 ); } for (x=0; x<2; x++) // x=0: snps, x=1: indels { gtcmp_t *stats; if ( x==0 ) { printf("# GCsS, Genotype concordance by sample (SNPs)\n# GCsS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared\n"); stats = args->smpl_gts_snps; } else { printf("# GCiS, Genotype concordance by sample (indels)\n# GCiS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared\n"); stats = args->smpl_gts_indels; } for (i=0; ifiles->n_smpl; i++) { uint64_t mm = 0, m = stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HET_RA)] + stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HOM_AA)]; for (j=0; j<3; j++) for (k=0; k<3; k++) if ( j!=k ) mm += stats[i].gt2gt[j][k]; // Pearson's r2 double r2 = 0; if ( stats[i].n ) { r2 = (stats[i].yx - stats[i].x*stats[i].y/stats[i].n); r2 /= sqrt((stats[i].xx - stats[i].x*stats[i].x/stats[i].n) * (stats[i].yy - stats[i].y*stats[i].y/stats[i].n)); r2 *= r2; } printf("GC%cS\t2\t%s\t%.3f", x==0 ? 's' : 'i', args->files->samples[i], m+mm ? mm*100.0/(m+mm) : 0); printf("\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"", stats[i].gt2gt[T2S(GT_HOM_RR)][T2S(GT_HOM_RR)], stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HET_RA)], stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HOM_AA)]); printf("\t%"PRIu64"\t%"PRIu64"\t%"PRIu64"", stats[i].gt2gt[T2S(GT_HOM_RR)][T2S(GT_HET_RA)] + stats[i].gt2gt[T2S(GT_HOM_RR)][T2S(GT_HOM_AA)], stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HOM_RR)] + stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HOM_AA)], stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HOM_RR)] + stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HET_RA)]); if ( stats[i].n && !isnan(r2) ) printf("\t%f\n", r2); else printf("\t"NA_STRING"\n"); } } for (x=0; x<2; x++) // x=0: snps, x=1: indels { //printf("# GCiS, Genotype concordance by sample (indels)\n# GCiS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared\n"); gtcmp_t *stats; if ( x==0 ) { printf("# GCTs, Genotype concordance table (SNPs)\n# GCTs"); stats = args->smpl_gts_snps; } else { printf("# GCTi, Genotype concordance table (indels)\n# GCTi"); stats = args->smpl_gts_indels; } i = 1; printf("\t[%d]sample", ++i); printf("\t[%d]RR Hom -> RR Hom", ++i); printf("\t[%d]RR Hom -> RA Het", ++i); printf("\t[%d]RR Hom -> AA Hom", ++i); printf("\t[%d]RR Hom -> AA Het", ++i); printf("\t[%d]RR Hom -> missing", ++i); printf("\t[%d]RA Het -> RR Hom", ++i); printf("\t[%d]RA Het -> RA Het", ++i); printf("\t[%d]RA Het -> AA Hom", ++i); printf("\t[%d]RA Het -> AA Het", ++i); printf("\t[%d]RA Het -> missing", ++i); printf("\t[%d]AA Hom -> RR Hom", ++i); printf("\t[%d]AA Hom -> RA Het", ++i); printf("\t[%d]AA Hom -> AA Hom", ++i); printf("\t[%d]AA Hom -> AA Het", ++i); printf("\t[%d]AA Hom -> missing", ++i); printf("\t[%d]AA Het -> RR Hom", ++i); printf("\t[%d]AA Het -> RA Het", ++i); printf("\t[%d]AA Het -> AA Hom", ++i); printf("\t[%d]AA Het -> AA Het", ++i); printf("\t[%d]AA Het -> missing", ++i); printf("\t[%d]missing -> RR Hom", ++i); printf("\t[%d]missing -> RA Het", ++i); printf("\t[%d]missing -> AA Hom", ++i); printf("\t[%d]missing -> AA Het", ++i); printf("\t[%d]missing -> missing\n", ++i); for (i=0; ifiles->n_smpl; i++) { printf("GCT%c\t%s", x==0 ? 's' : 'i', args->files->samples[i]); for (j=0; j<5; j++) for (k=0; k<5; k++) printf("\t%"PRIu64, stats[i].gt2gt[j][k]); printf("\n"); } } } printf("# DP, depth:\n" "# - set id, see above\n" "# - the depth bin, corresponds to the depth (unless --depth was given)\n" "# - number of genotypes with this depth (zero unless -s/-S was given)\n" "# - fraction of genotypes with this depth (zero unless -s/-S was given)\n" "# - number of sites with this depth\n" "# - fraction of sites with this depth\n"); printf("# DP, Depth distribution\n# DP\t[2]id\t[3]bin\t[4]number of genotypes\t[5]fraction of genotypes (%%)\t[6]number of sites\t[7]fraction of sites (%%)\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; long unsigned int sum = 0, sum_sites = 0; for (i=0; idp.m_vals; i++) { sum += stats->dp.vals[i]; sum_sites += stats->dp_sites.vals[i]; } for (i=0; idp.m_vals; i++) { if ( stats->dp.vals[i]==0 && stats->dp_sites.vals[i]==0 ) continue; printf("DP\t%d\t", id); if ( i==0 ) printf("<%d", stats->dp.min); else if ( i+1==stats->dp.m_vals ) printf(">%d", stats->dp.max); else printf("%d", idist_i2bin(&stats->dp,i)); printf("\t%"PRIu64"\t%f", stats->dp.vals[i], sum ? stats->dp.vals[i]*100./sum : 0); printf("\t%"PRIu64"\t%f\n", stats->dp_sites.vals[i], sum_sites ? stats->dp_sites.vals[i]*100./sum_sites : 0); } } if ( args->files->n_smpl ) { printf("# PSC, Per-sample counts. Note that the ref/het/hom counts include only SNPs, for indels see PSI. The rest include both SNPs and indels.\n"); printf("# PSC\t[2]id\t[3]sample\t[4]nRefHom\t[5]nNonRefHom\t[6]nHets\t[7]nTransitions\t[8]nTransversions\t[9]nIndels\t[10]average depth\t[11]nSingletons" "\t[12]nHapRef\t[13]nHapAlt\t[14]nMissing\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; for (i=0; ifiles->n_smpl; i++) { float dp = stats->smpl_ndp[i] ? stats->smpl_dp[i]/(float)stats->smpl_ndp[i] : 0; printf("PSC\t%d\t%s\t%d\t%d\t%d\t%d\t%d\t%d\t%.1f\t%d\t%d\t%d\t%d\n", id,args->files->samples[i], stats->smpl_homRR[i], stats->smpl_homAA[i], stats->smpl_hets[i], stats->smpl_ts[i], stats->smpl_tv[i], stats->smpl_indels[i],dp, stats->smpl_sngl[i], stats->smpl_hapRef[i], stats->smpl_hapAlt[i], stats->smpl_missing[i]); } } printf("# PSI, Per-Sample Indels. Note that alt-het genotypes with both ins and del allele are counted twice, in both nInsHets and nDelHets.\n"); printf("# PSI\t[2]id\t[3]sample\t[4]in-frame\t[5]out-frame\t[6]not applicable\t[7]out/(in+out) ratio\t[8]nInsHets\t[9]nDelHets\t[10]nInsAltHoms\t[11]nDelAltHoms\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; for (i=0; ifiles->n_smpl; i++) { int na = 0, in = 0, out = 0; if ( args->exons ) { na = stats->smpl_frm_shifts[i*3 + 0]; in = stats->smpl_frm_shifts[i*3 + 1]; out = stats->smpl_frm_shifts[i*3 + 2]; } printf("PSI\t%d\t%s\t%d\t%d\t%d\t%.2f\t%d\t%d\t%d\t%d\n", id,args->files->samples[i], in,out,na,in+out?1.0*out/(in+out):0, stats->smpl_ins_hets[i],stats->smpl_del_hets[i],stats->smpl_ins_homs[i],stats->smpl_del_homs[i]); } } #ifdef HWE_STATS printf("# HWE\n# HWE\t[2]id\t[3]1st ALT allele frequency\t[4]Number of observations\t[5]25th percentile\t[6]median\t[7]75th percentile\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; for (i=0; inaf_hwe; i++) stats->af_hwe[i+args->naf_hwe] += stats->af_hwe[i]; // singletons for (i=1; im_af; i++) { unsigned int sum_tot = 0, sum_tmp = 0; int j, *ptr = &stats->af_hwe[i*args->naf_hwe]; for (j=0; jnaf_hwe; j++) sum_tot += ptr[j]; if ( !sum_tot ) continue; double af = args->af_bins ? (bin_get_value(args->af_bins,i)+bin_get_value(args->af_bins,i-1))*0.5 : (double)(i-1)/(args->m_af-1); int nprn = 3; printf("HWE\t%d\t%f\t%d",id,af,sum_tot); for (j=0; jnaf_hwe; j++) { sum_tmp += ptr[j]; float frac = (float)sum_tmp/sum_tot; if ( frac >= 0.75 ) { while (nprn>0) { printf("\t%f", (float)j/args->naf_hwe); nprn--; } break; } if ( frac >= 0.5 ) { while (nprn>1) { printf("\t%f", (float)j/args->naf_hwe); nprn--; } continue; } if ( frac >= 0.25 ) { while (nprn>2) { printf("\t%f", (float)j/args->naf_hwe); nprn--; } } } assert(nprn==0); printf("\n"); } } #endif } if ( args->stats[0].smpl_vaf ) { printf("# VAF, Variant Allele Frequency determined as fraction of alternate reads in FORMAT/AD\n"); printf("# VAF\t[2]id\t[3]sample\t[4]SNV VAF distribution\t[5]indel VAF distribution\n"); for (id=0; idnstats; id++) { stats_t *stats = &args->stats[id]; for (i=0; ifiles->n_smpl; i++) { printf("VAF\t%d\t%s\t", id,args->files->samples[i]); for (j=0; j<21; j++) printf("%s%d",j?",":"",stats->smpl_vaf[i].snv[j]); printf("\t"); for (j=0; j<21; j++) printf("%s%d",j?",":"",stats->smpl_vaf[i].indel[j]); printf("\n"); } } } } static void usage(void) { fprintf(stderr, "\n"); fprintf(stderr, "About: Parses VCF or BCF and produces stats which can be plotted using plot-vcfstats.\n"); fprintf(stderr, " When two files are given, the program generates separate stats for intersection\n"); fprintf(stderr, " and the complements. By default only sites are compared, -s/-S must given to include\n"); fprintf(stderr, " also sample columns.\n"); fprintf(stderr, "Usage: bcftools stats [options] []\n"); fprintf(stderr, "\n"); fprintf(stderr, "Options:\n"); fprintf(stderr, " --af-bins LIST Allele frequency bins, a list (0.1,0.5,1) or a file (0.1\\n0.5\\n1)\n"); fprintf(stderr, " --af-tag STRING Allele frequency tag to use, by default estimated from AN,AC or GT\n"); fprintf(stderr, " -1, --1st-allele-only Include only 1st allele at multiallelic sites\n"); fprintf(stderr, " -c, --collapse STRING Treat as identical records with , see man page for details [none]\n"); fprintf(stderr, " -d, --depth INT,INT,INT Depth distribution: min,max,bin size [0,500,1]\n"); fprintf(stderr, " -e, --exclude EXPR Exclude sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -E, --exons FILE.gz Tab-delimited file with exons for indel frameshifts (chr,beg,end; 1-based, inclusive, bgzip compressed)\n"); fprintf(stderr, " -f, --apply-filters LIST Require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); fprintf(stderr, " -F, --fasta-ref FILE Faidx indexed reference sequence file to determine INDEL context\n"); fprintf(stderr, " -i, --include EXPR Select sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -I, --split-by-ID Collect stats for sites with ID separately (known vs novel)\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in a file\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -s, --samples LIST List of samples for sample stats, \"-\" to include all samples\n"); fprintf(stderr, " -S, --samples-file FILE File of samples to include\n"); fprintf(stderr, " -t, --targets REGION Similar to -r but streams rather than index-jumps\n"); fprintf(stderr, " -T, --targets-file FILE Similar to -R but streams rather than index-jumps\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " -u, --user-tstv TAG[:min:max:n] Collect Ts/Tv stats for any tag using the given binning [0:1:100]\n"); fprintf(stderr, " A subfield can be selected as e.g. 'PV4[0]', here the first value of the PV4 tag\n"); fprintf(stderr, " --threads INT Use multithreading with worker threads [0]\n"); fprintf(stderr, " -v, --verbose Produce verbose per-site and per-sample output\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfstats(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->files = bcf_sr_init(); args->argc = argc; args->argv = argv; args->dp_min = 0; args->dp_max = 500; args->dp_step = 1; int regions_is_file = 0, targets_is_file = 0; int regions_overlap = 1; int targets_overlap = 0; static struct option loptions[] = { {"af-bins",1,0,1}, {"af-tag",1,0,2}, {"1st-allele-only",0,0,'1'}, {"include",1,0,'i'}, {"exclude",1,0,'e'}, {"help",0,0,'h'}, {"collapse",1,0,'c'}, {"regions",1,0,'r'}, {"regions-file",1,0,'R'}, {"regions-overlap",required_argument,NULL,3}, {"verbose",0,0,'v'}, {"depth",1,0,'d'}, {"apply-filters",1,0,'f'}, {"exons",1,0,'E'}, {"samples",1,0,'s'}, {"samples-file",1,0,'S'}, {"split-by-ID",0,0,'I'}, {"targets",1,0,'t'}, {"targets-file",1,0,'T'}, {"targets-overlap",required_argument,NULL,4}, {"fasta-ref",1,0,'F'}, {"user-tstv",1,0,'u'}, {"threads",1,0,9}, {0,0,0,0} }; while ((c = getopt_long(argc, argv, "hc:r:R:e:s:S:d:i:t:T:F:f:1u:vIE:",loptions,NULL)) >= 0) { switch (c) { case 1 : args->af_bins_list = optarg; break; case 2 : args->af_tag = optarg; break; case 'u': add_user_stats(args,optarg); break; case '1': args->first_allele_only = 1; break; case 'F': args->ref_fname = optarg; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'c': if ( !strcmp(optarg,"snps") ) args->files->collapse |= COLLAPSE_SNPS; else if ( !strcmp(optarg,"indels") ) args->files->collapse |= COLLAPSE_INDELS; else if ( !strcmp(optarg,"both") ) args->files->collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; else if ( !strcmp(optarg,"any") ) args->files->collapse |= COLLAPSE_ANY; else if ( !strcmp(optarg,"all") ) args->files->collapse |= COLLAPSE_ANY; else if ( !strcmp(optarg,"some") ) args->files->collapse |= COLLAPSE_SOME; else if ( !strcmp(optarg,"none") ) args->files->collapse = COLLAPSE_NONE; else error("The --collapse string \"%s\" not recognised.\n", optarg); break; case 'v': args->verbose_sites = 1; break; case 'd': if ( sscanf(optarg,"%d,%d,%d",&args->dp_min,&args->dp_max,&args->dp_step)!=3 ) error("Could not parse --depth %s\n", optarg); if ( args->dp_min<0 || args->dp_min >= args->dp_max || args->dp_step > args->dp_max - args->dp_min + 1 ) error("Is this a typo? --depth %s\n", optarg); break; case 'f': args->files->apply_filters = optarg; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 'E': args->exons_fname = optarg; break; case 's': args->samples_list = optarg; break; case 'S': args->samples_list = optarg; args->samples_is_file = 1; break; case 'I': args->split_by_id = 1; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 3 : regions_overlap = parse_overlap_option(optarg); if ( regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 4 : targets_overlap = parse_overlap_option(optarg); if ( targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 'h': case '?': usage(); break; default: error("Unknown argument: %s\n", optarg); } } char *fname = NULL; if ( optind==argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(); } else fname = argv[optind]; if ( argc-optind>2 ) usage(); if ( argc-optind>1 ) { args->files->require_index = 1; if ( args->split_by_id ) error("Only one file can be given with -i.\n"); } if ( !args->samples_list ) args->files->max_unpack = BCF_UN_INFO; else args->files->max_unpack = BCF_UN_FMT; if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( args->regions_list) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } if ( args->n_threads && bcf_sr_set_threads(args->files, args->n_threads)<0) error("Failed to create threads\n"); while (fname) { if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); fname = ++optind < argc ? argv[optind] : NULL; } init_stats(args); print_header(args); do_vcf_stats(args); print_stats(args); destroy_stats(args); bcf_sr_destroy(args->files); free(args); return 0; } bcftools-1.21/vcfview.c000066400000000000000000001167221467060157400151100ustar00rootroot00000000000000/* vcfview.c -- VCF/BCF conversion, view, subset and filter VCF/BCF files. Copyright (C) 2013-2023 Genome Research Ltd. Author: Shane McCarthy Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include #include "bcftools.h" #include "filter.h" #include "htslib/khash_str2int.h" #define FLT_INCLUDE 1 #define FLT_EXCLUDE 2 #define ALLELE_NONREF 1 #define ALLELE_MINOR 2 #define ALLELE_ALT1 3 #define ALLELE_MAJOR 4 #define ALLELE_NONMAJOR 5 #define GT_NEED_HOM 1 #define GT_NEED_HET 2 #define GT_NO_HOM 3 #define GT_NO_HET 4 #define GT_NEED_MISSING 5 #define GT_NO_MISSING 6 typedef struct _args_t { filter_t *filter; char *filter_str; int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) bcf_srs_t *files; bcf_hdr_t *hdr, *hnull, *hsub; // original header, sites-only header, subset header char **argv, *format, *sample_names, *subset_fname, *targets_list, *regions_list; int regions_overlap, targets_overlap; int argc, clevel, n_threads, output_type, print_header, update_info, header_only, n_samples, *imap, calc_ac; int trim_alts, sites_only, known, novel, min_alleles, max_alleles, private_vars, uncalled, phased; int min_ac, min_ac_type, max_ac, max_ac_type, min_af_type, max_af_type, gt_type; int *ac, mac; float min_af, max_af; char *fn_ref, *fn_out, **samples; int sample_is_file, force_samples; char *include_types, *exclude_types; int include, exclude; int record_cmd_line; char *index_fn; int write_index; int trim_star_allele; htsFile *out; } args_t; static void init_data(args_t *args) { int i; args->hdr = args->files->readers[0].header; if (args->calc_ac && args->update_info) { if (bcf_hdr_append(args->hdr,"##INFO=") < 0) error_errno("[%s] Failed to add \"AC\" INFO header", __func__); if (bcf_hdr_append(args->hdr,"##INFO=") < 0) error_errno("[%s] Failed to add \"AN\" INFO header", __func__); } if (args->record_cmd_line) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_view"); else if (bcf_hdr_sync(args->hdr) < 0) error_errno("[%s] Failed to update header", __func__); // setup sample data if (args->sample_names) { void *hdr_samples = khash_str2int_init(); for (i=0; ihdr); i++) khash_str2int_inc(hdr_samples, bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,i)); void *exclude = (args->sample_names[0]=='^') ? khash_str2int_init() : NULL; int nsmpl; char **smpl = NULL; args->samples = NULL; args->n_samples = 0; smpl = hts_readlist(exclude ? &args->sample_names[1] : args->sample_names, args->sample_is_file, &nsmpl); if ( !smpl ) { error("Could not read the list: \"%s\"\n", exclude ? &args->sample_names[1] : args->sample_names); } if ( exclude ) { for (i=0; iforce_samples) { fprintf(stderr, "Warn: exclude called for sample that does not exist in header: \"%s\"... skipping\n", smpl[i]); } else { error("Error: exclude called for sample that does not exist in header: \"%s\". Use \"--force-samples\" to ignore this error.\n", smpl[i]); } } khash_str2int_inc(exclude, smpl[i]); } for (i=0; ihdr); i++) { if ( exclude && khash_str2int_has_key(exclude,bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,i)) ) continue; args->samples = (char**) realloc(args->samples, (args->n_samples+1)*sizeof(const char*)); args->samples[args->n_samples++] = strdup(bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,i)); } khash_str2int_destroy(exclude); } else { for (i=0; iforce_samples) { fprintf(stderr, "Warn: subset called for sample that does not exist in header: \"%s\"... skipping\n", smpl[i]); continue; } else { error("Error: subset called for sample that does not exist in header: \"%s\". Use \"--force-samples\" to ignore this error.\n", smpl[i]); } } args->samples = (char**) realloc(args->samples, (args->n_samples+1)*sizeof(const char*)); args->samples[args->n_samples++] = strdup(smpl[i]); } } for (i=0; in_samples == 0) { fprintf(stderr, "Warn: subsetting has removed all samples\n"); args->sites_only = 1; } } if (args->n_samples) args->imap = (int*)malloc(args->n_samples * sizeof(int)); // determine variant types to include/exclude if (args->include_types || args->exclude_types) { if (args->include_types && args->exclude_types) { fprintf(stderr, "Error: only supply one of --include-types, --exclude-types options\n"); exit(1); } char **type_list = 0; int m = 0, n = 0; const char *q, *p; for (q = p = args->include_types ? args->include_types : args->exclude_types;; ++p) { if (*p == ',' || *p == 0) { if (m == n) { m = m? m<<1 : 16; type_list = (char**)realloc(type_list, m * sizeof(char*)); } type_list[n] = (char*)calloc(p - q + 1, 1); strncpy(type_list[n++], q, p - q); q = p + 1; if (*p == 0) break; } } type_list = (char**)realloc(type_list, n * sizeof(char*)); if (args->include_types) { args->include = 0; for (i = 0; i < n; ++i) { if (strcmp(type_list[i], "snps") == 0) args->include |= VCF_SNP<<1; else if (strcmp(type_list[i], "indels") == 0) args->include |= VCF_INDEL<<1; else if (strcmp(type_list[i], "mnps") == 0) args->include |= VCF_MNP<<1; else if (strcmp(type_list[i], "other") == 0) args->include |= VCF_OTHER<<1; else if (strcmp(type_list[i], "ref") == 0) args->include |= VCF_OTHER<<1; else if (strcmp(type_list[i], "bnd") == 0) args->include |= VCF_BND<<1; else { fprintf(stderr, "[E::%s] unknown type\n", type_list[i]); fprintf(stderr, "Accepted types are snps, indels, mnps, other\n"); exit(1); } } } if (args->exclude_types) { args->exclude = 0; for (i = 0; i < n; ++i) { if (strcmp(type_list[i], "snps") == 0) args->exclude |= VCF_SNP<<1; else if (strcmp(type_list[i], "indels") == 0) args->exclude |= VCF_INDEL<<1; else if (strcmp(type_list[i], "mnps") == 0) args->exclude |= VCF_MNP<<1; else if (strcmp(type_list[i], "other") == 0) args->exclude |= VCF_OTHER<<1; else if (strcmp(type_list[i], "ref") == 0) args->exclude |= VCF_OTHER<<1; else if (strcmp(type_list[i], "bnd") == 0) args->exclude |= VCF_BND<<1; else { fprintf(stderr, "[E::%s] unknown type\n", type_list[i]); fprintf(stderr, "Accepted types are snps, indels, mnps, other\n"); exit(1); } } } for (i = 0; i < n; ++i) free(type_list[i]); free(type_list); } char wmode[8]; set_wmode(wmode,args->output_type,args->fn_out,args->clevel); args->out = hts_open(args->fn_out ? args->fn_out : "-", wmode); if ( !args->out ) error("%s: %s\n", args->fn_out,strerror(errno)); if ( args->n_threads > 0) hts_set_opt(args->out, HTS_OPT_THREAD_POOL, args->files->p); // headers: hdr=full header, hsub=subset header, hnull=sites only header if (args->sites_only){ args->hnull = bcf_hdr_subset(args->hdr, 0, 0, 0); bcf_hdr_remove(args->hnull, BCF_HL_FMT, NULL); } if (args->n_samples > 0) { args->hsub = bcf_hdr_subset(args->hdr, args->n_samples, args->samples, args->imap); if ( !args->hsub ) error("Error occurred while subsetting samples\n"); if ( args->n_samples != bcf_hdr_nsamples(args->hsub) ) { int i; for (i=0; in_samples; i++) if ( args->imap[i]<0 ) error("Error: No such sample: \"%s\"\n", args->samples[i]); } } if ( args->filter_str ) args->filter = filter_init(args->hdr, args->filter_str); } static void destroy_data(args_t *args) { int i; if ( args->imap ) { for (i = 0; i < args->n_samples; ++i) free(args->samples[i]); free(args->samples); free(args->imap); } if (args->hnull) bcf_hdr_destroy(args->hnull); if (args->hsub) bcf_hdr_destroy(args->hsub); if ( args->filter ) filter_destroy(args->filter); free(args->ac); } // true if all samples are phased. // haploid genotypes are considered phased // ./. => not phased, .|. => phased int bcf_all_phased(const bcf_hdr_t *header, bcf1_t *line) { bcf_unpack(line, BCF_UN_FMT); bcf_fmt_t *fmt_ptr = bcf_get_fmt(header, line, "GT"); int all_phased = 1; if ( fmt_ptr ) { int i, isample; for (isample=0; isamplen_sample; isample++) { int sample_phased = 0; #define BRANCH_INT(type_t,vector_end) { \ type_t *p = (type_t*) (fmt_ptr->p + isample*fmt_ptr->size); \ for (i=0; in; i++) \ { \ if (fmt_ptr->n == 1 || (p[i] == vector_end && i == 1)) { sample_phased = 1; break; } /* haploid phased by definition */ \ if ( p[i] == vector_end ) { break; }; /* smaller ploidy */ \ if ( bcf_gt_is_missing(p[i]) ) continue; /* missing allele */ \ if ((p[i])&1) { \ sample_phased = 1; \ break; \ } \ } \ } switch (fmt_ptr->type) { case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break; case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break; case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break; default: fprintf(stderr, "[E::%s] todo: fmt_type %d\n", __func__, fmt_ptr->type); exit(1); break; } #undef BRANCH_INT if (!sample_phased) { all_phased = 0; break; } } } return all_phased; } int subset_vcf(args_t *args, bcf1_t *line) { if ( args->min_alleles && line->n_allele < args->min_alleles ) return 0; // min alleles if ( args->max_alleles && line->n_allele > args->max_alleles ) return 0; // max alleles if (args->novel || args->known) { if ( args->novel && (line->d.id[0]!='.' || line->d.id[1]!=0) ) return 0; // skip sites which are known, ID != '.' if ( args->known && line->d.id[0]=='.' && line->d.id[1]==0 ) return 0; // skip sites which are novel, ID == '.' } if (args->include || args->exclude) { int line_type = bcf_get_variant_types(line); if ( args->include && !((line_type<<1) & args->include) ) return 0; // include only given variant types if ( args->exclude && (line_type<<1) & args->exclude ) return 0; // exclude given variant types } if ( args->filter ) { int ret = filter_test(args->filter, line, NULL); if ( args->filter_logic==FLT_INCLUDE ) { if ( !ret ) return 0; } else if ( ret ) return 0; } hts_expand(int, line->n_allele, args->mac, args->ac); int i, an = 0, non_ref_ac = 0; if (args->calc_ac) { bcf_calc_ac(args->hdr, line, args->ac, BCF_UN_INFO|BCF_UN_FMT); // get original AC and AN values from INFO field if available, otherwise calculate for (i=1; in_allele; i++) non_ref_ac += args->ac[i]; for (i=0; in_allele; i++) an += args->ac[i]; } int update_ac = args->calc_ac; if (args->n_samples) { int non_ref_ac_sub = 0, *ac_sub = (int*) calloc(line->n_allele,sizeof(int)); bcf_subset(args->hdr, line, args->n_samples, args->imap); if ( args->calc_ac && !bcf_get_fmt(args->hdr,line,"GT") ) update_ac = 0; if ( update_ac ) { bcf_calc_ac(args->hsub, line, ac_sub, BCF_UN_FMT); // recalculate AC and AN an = 0; for (i=0; in_allele; i++) { args->ac[i] = ac_sub[i]; an += ac_sub[i]; } for (i=1; in_allele; i++) non_ref_ac_sub += ac_sub[i]; if (args->private_vars) { if (args->private_vars == FLT_INCLUDE && !(non_ref_ac_sub > 0 && non_ref_ac == non_ref_ac_sub)) { free(ac_sub); return 0; } // select private sites if (args->private_vars == FLT_EXCLUDE && non_ref_ac_sub > 0 && non_ref_ac == non_ref_ac_sub) { free(ac_sub); return 0; } // exclude private sites } non_ref_ac = non_ref_ac_sub; } free(ac_sub); } bcf_fmt_t *gt_fmt; if ( args->gt_type && (gt_fmt=bcf_get_fmt(args->hdr,line,"GT")) ) { int nhet = 0, nhom = 0, nmiss = 0; for (i=0; ihdr); i++) { int type = bcf_gt_type(gt_fmt,i,NULL,NULL); if ( type==GT_HET_RA || type==GT_HET_AA ) { if ( args->gt_type==GT_NO_HET ) return 0; nhet = 1; } else if ( type==GT_UNKN ) { if ( args->gt_type==GT_NO_MISSING ) return 0; nmiss = 1; } else { if ( args->gt_type==GT_NO_HOM ) return 0; nhom = 1; } } if ( args->gt_type==GT_NEED_HOM && !nhom ) return 0; else if ( args->gt_type==GT_NEED_HET && !nhet ) return 0; else if ( args->gt_type==GT_NEED_MISSING && !nmiss ) return 0; } int minor_ac = 0; int major_ac = 0; if ( args->calc_ac ) { minor_ac = args->ac[0]; major_ac = args->ac[0]; for (i=1; in_allele; i++){ if (args->ac[i] < minor_ac) { minor_ac = args->ac[i]; } if (args->ac[i] > major_ac) { major_ac = args->ac[i]; } } } if (args->min_ac!=-1) { if (args->min_ac_type == ALLELE_NONREF && args->min_ac>non_ref_ac) return 0; // min AC else if (args->min_ac_type == ALLELE_MINOR && args->min_ac>minor_ac) return 0; // min minor AC else if (args->min_ac_type == ALLELE_ALT1 && args->min_ac>args->ac[1]) return 0; // min 1st alternate AC else if (args->min_ac_type == ALLELE_MAJOR && args->min_ac > major_ac) return 0; // min major AC else if (args->min_ac_type == ALLELE_NONMAJOR && args->min_ac > an-major_ac) return 0; // min non-major AC } if (args->max_ac!=-1) { if (args->max_ac_type == ALLELE_NONREF && args->max_acmax_ac_type == ALLELE_MINOR && args->max_acmax_ac_type == ALLELE_ALT1 && args->max_acac[1]) return 0; // max 1st alternate AC else if (args->max_ac_type == ALLELE_MAJOR && args->max_ac < major_ac) return 0; // max major AC else if (args->max_ac_type == ALLELE_NONMAJOR && args->max_ac < an-major_ac) return 0; // max non-major AC } if (args->min_af!=-1) { if (an == 0) return 0; // freq not defined, skip site if (args->min_af_type == ALLELE_NONREF && args->min_af>non_ref_ac/(double)an) return 0; // min AF else if (args->min_af_type == ALLELE_MINOR && args->min_af>minor_ac/(double)an) return 0; // min minor AF else if (args->min_af_type == ALLELE_ALT1 && args->min_af>args->ac[1]/(double)an) return 0; // min 1st alternate AF else if (args->min_af_type == ALLELE_MAJOR && args->min_af > major_ac/(double)an) return 0; // min major AF else if (args->min_af_type == ALLELE_NONMAJOR && args->min_af > (an-major_ac)/(double)an) return 0; // min non-major AF } if (args->max_af!=-1) { if (an == 0) return 0; // freq not defined, skip site if (args->max_af_type == ALLELE_NONREF && args->max_afmax_af_type == ALLELE_MINOR && args->max_afmax_af_type == ALLELE_ALT1 && args->max_afac[1]/(double)an) return 0; // max 1st alternate AF else if (args->max_af_type == ALLELE_MAJOR && args->max_af < major_ac/(double)an) return 0; // max major AF else if (args->max_af_type == ALLELE_NONMAJOR && args->max_af < (an-major_ac)/(double)an) return 0; // max non-major AF } if (args->uncalled) { if (args->uncalled == FLT_INCLUDE && an > 0) return 0; // select uncalled if (args->uncalled == FLT_EXCLUDE && an == 0) return 0; // skip if uncalled } if (update_ac && args->update_info) { bcf_update_info_int32(args->hdr, line, "AC", &args->ac[1], line->n_allele-1); bcf_update_info_int32(args->hdr, line, "AN", &an, 1); } if (args->trim_alts) { int ret = bcf_trim_alleles(args->hsub ? args->hsub : args->hdr, line); if ( ret<0 ) error("Error: Could not trim alleles at %s:%"PRId64"\n", bcf_seqname(args->hsub ? args->hsub : args->hdr, line), (int64_t) line->pos+1); } if (args->trim_star_allele) { int iunseen; if ( args->trim_star_allele && (line->n_allele > 2 || args->trim_star_allele > 1) && (iunseen=get_unseen_allele(line)) && iunseen>0 ) { // the unobserved star allele should be trimmed, either it is variant site or trimming of all sites was requested kbitset_t *rm_set = kbs_init(line->n_allele); kbs_insert(rm_set, iunseen); if ( bcf_remove_allele_set(args->hdr,line,rm_set) ) error("[%s] Error: failed to trim the unobserved allele at %s:%"PRIhts_pos"\n",__func__,bcf_seqname(args->hdr,line),line->pos+1); kbs_destroy(rm_set); } } if (args->phased) { int phased = bcf_all_phased(args->hdr, line); if (args->phased == FLT_INCLUDE && !phased) { return 0; } // skip unphased if (args->phased == FLT_EXCLUDE && phased) { return 0; } // skip phased } if (args->sites_only) bcf_subset(args->hsub ? args->hsub : args->hdr, line, 0, 0); return 1; } void set_allele_type (int *atype, char *atype_string) { *atype = ALLELE_NONREF; if (strcmp(atype_string, "minor") == 0) { *atype = ALLELE_MINOR; } else if (strcmp(atype_string, "alt1") == 0) { *atype = ALLELE_ALT1; } else if (strcmp(atype_string, "nref") == 0) { *atype = ALLELE_NONREF; } else if (strcmp(atype_string, "major") == 0) { *atype = ALLELE_MAJOR; } else if (strcmp(atype_string, "nonmajor") == 0) { *atype = ALLELE_NONMAJOR; } else { error("Error: allele type not recognised. Expected one of nref|alt1|minor|major|nonmajor, got \"%s\".\n", atype_string); } } static void usage(args_t *args) { fprintf(stderr, "\n"); fprintf(stderr, "About: VCF/BCF conversion, view, subset and filter VCF/BCF files.\n"); fprintf(stderr, "Usage: bcftools view [options] [region1 [...]]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Output options:\n"); fprintf(stderr, " -G, --drop-genotypes Drop individual genotype information (after subsetting if -s option set)\n"); fprintf(stderr, " -h, --header-only Print only the header in VCF output (equivalent to bcftools head)\n"); fprintf(stderr, " -H, --no-header Suppress the header in VCF output\n"); fprintf(stderr, " --with-header Print both header and records in VCF output [default]\n"); fprintf(stderr, " -l, --compression-level [0-9] Compression level: 0 uncompressed, 1 best speed, 9 best compression [%d]\n", args->clevel); fprintf(stderr, " --no-version Do not append version and command line to the header\n"); fprintf(stderr, " -o, --output FILE Output file name [stdout]\n"); fprintf(stderr, " -O, --output-type u|b|v|z[0-9] u/b: un/compressed BCF, v/z: un/compressed VCF, 0-9: compression level [v]\n"); fprintf(stderr, " -r, --regions REGION Restrict to comma-separated list of regions\n"); fprintf(stderr, " -R, --regions-file FILE Restrict to regions listed in FILE\n"); fprintf(stderr, " --regions-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [1]\n"); fprintf(stderr, " -t, --targets [^]REGION Similar to -r but streams rather than index-jumps. Exclude regions with \"^\" prefix\n"); fprintf(stderr, " -T, --targets-file [^]FILE Similar to -R but streams rather than index-jumps. Exclude regions with \"^\" prefix\n"); fprintf(stderr, " --targets-overlap 0|1|2 Include if POS in the region (0), record overlaps (1), variant overlaps (2) [0]\n"); fprintf(stderr, " --threads INT Use multithreading with INT worker threads [0]\n"); fprintf(stderr, "\n"); fprintf(stderr, "Subset options:\n"); fprintf(stderr, " -A, --trim-unseen-allele Remove '<*>' or '' at variant (-A) or at all (-AA) sites\n"); fprintf(stderr, " -a, --trim-alt-alleles Trim ALT alleles not seen in the genotype fields (or their subset with -s/-S)\n"); fprintf(stderr, " -I, --no-update Do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN)\n"); fprintf(stderr, " -s, --samples [^]LIST Comma separated list of samples to include (or exclude with \"^\" prefix). Be careful\n"); fprintf(stderr, " when combining filtering with sample subsetting as filtering comes (usually) first.\n"); fprintf(stderr, " If unsure, split sample subsetting and filtering in two commands, using -Ou when piping.\n"); fprintf(stderr, " -S, --samples-file [^]FILE File of samples to include (or exclude with \"^\" prefix)\n"); fprintf(stderr, " --force-samples Only warn about unknown subset samples\n"); fprintf(stderr, "\n"); fprintf(stderr, "Filter options:\n"); fprintf(stderr, " -c/C, --min-ac/--max-ac INT[:TYPE] Minimum/maximum count for non-reference (nref), 1st alternate (alt1), least frequent\n"); fprintf(stderr, " (minor), most frequent (major) or sum of all but most frequent (nonmajor) alleles [nref]\n"); fprintf(stderr, " -f, --apply-filters LIST Require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); fprintf(stderr, " -g, --genotype [^]hom|het|miss Require one or more hom/het/missing genotype or, if prefixed with \"^\", exclude such sites\n"); fprintf(stderr, " -i/e, --include/--exclude EXPR Select/exclude sites for which the expression is true (see man page for details)\n"); fprintf(stderr, " -k/n, --known/--novel Select known/novel sites only (ID is not/is '.')\n"); fprintf(stderr, " -m/M, --min-alleles/--max-alleles INT Minimum/maximum number of alleles listed in REF and ALT (e.g. -m2 -M2 for biallelic sites)\n"); fprintf(stderr, " -p/P, --phased/--exclude-phased Select/exclude sites where all samples are phased\n"); fprintf(stderr, " -q/Q, --min-af/--max-af FLOAT[:TYPE] Minimum/maximum frequency for non-reference (nref), 1st alternate (alt1), least frequent\n"); fprintf(stderr, " (minor), most frequent (major) or sum of all but most frequent (nonmajor) alleles [nref]\n"); fprintf(stderr, " -u/U, --uncalled/--exclude-uncalled Select/exclude sites without a called genotype\n"); fprintf(stderr, " -v/V, --types/--exclude-types LIST Select/exclude comma-separated list of variant types: snps,indels,mnps,ref,bnd,other [null]\n"); fprintf(stderr, " -x/X, --private/--exclude-private Select/exclude sites where the non-reference alleles are exclusive (private) to the subset samples\n"); fprintf(stderr, " -W, --write-index[=FMT] Automatically index the output files [off]\n"); fprintf(stderr, "\n"); exit(1); } int main_vcfview(int argc, char *argv[]) { int c; args_t *args = (args_t*) calloc(1,sizeof(args_t)); args->argc = argc; args->argv = argv; args->files = bcf_sr_init(); args->clevel = -1; args->print_header = 1; args->update_info = 1; args->output_type = FT_VCF; args->n_threads = 0; args->record_cmd_line = 1; args->write_index = 0; args->min_ac = args->max_ac = args->min_af = args->max_af = -1; args->regions_overlap = 1; args->targets_overlap = 0; int targets_is_file = 0, regions_is_file = 0; static struct option loptions[] = { {"genotype",required_argument,NULL,'g'}, {"compression-level",required_argument,NULL,'l'}, {"threads",required_argument,NULL,9}, {"header-only",no_argument,NULL,'h'}, {"no-header",no_argument,NULL,'H'}, {"with-header",no_argument,NULL,4}, {"exclude",required_argument,NULL,'e'}, {"include",required_argument,NULL,'i'}, {"trim-alt-alleles",no_argument,NULL,'a'}, {"trim-unseen-allele",no_argument,NULL,'A'}, {"no-update",no_argument,NULL,'I'}, {"drop-genotypes",no_argument,NULL,'G'}, {"private",no_argument,NULL,'x'}, {"exclude-private",no_argument,NULL,'X'}, {"uncalled",no_argument,NULL,'u'}, {"exclude-uncalled",no_argument,NULL,'U'}, {"apply-filters",required_argument,NULL,'f'}, {"known",no_argument,NULL,'k'}, {"novel",no_argument,NULL,'n'}, {"min-alleles",required_argument,NULL,'m'}, {"max-alleles",required_argument,NULL,'M'}, {"samples",required_argument,NULL,'s'}, {"samples-file",required_argument,NULL,'S'}, {"force-samples",no_argument,NULL,1}, {"output-type",required_argument,NULL,'O'}, {"output-file",required_argument,NULL,'o'}, {"output",required_argument,NULL,'o'}, {"types",required_argument,NULL,'v'}, {"exclude-types",required_argument,NULL,'V'}, {"targets",required_argument,NULL,'t'}, {"targets-file",required_argument,NULL,'T'}, {"targets-overlap",required_argument,NULL,2}, {"regions",required_argument,NULL,'r'}, {"regions-file",required_argument,NULL,'R'}, {"regions-overlap",required_argument,NULL,3}, {"min-ac",required_argument,NULL,'c'}, {"max-ac",required_argument,NULL,'C'}, {"min-af",required_argument,NULL,'q'}, {"max-af",required_argument,NULL,'Q'}, {"phased",no_argument,NULL,'p'}, {"exclude-phased",no_argument,NULL,'P'}, {"no-version",no_argument,NULL,8}, {"write-index",optional_argument,NULL,'W'}, {NULL,0,NULL,0} }; char *tmp; while ((c = getopt_long(argc, argv, "l:t:T:r:R:o:O:s:S:Gf:knv:V:m:M:aAuUhHc:C:Ii:e:xXpPq:Q:g:W::",loptions,NULL)) >= 0) { char allele_type[9] = "nref"; switch (c) { case 'O': switch (optarg[0]) { case 'b': args->output_type = FT_BCF_GZ; break; case 'u': args->output_type = FT_BCF; break; case 'z': args->output_type = FT_VCF_GZ; break; case 'v': args->output_type = FT_VCF; break; default: { args->clevel = strtol(optarg,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("The output type \"%s\" not recognised\n", optarg); } }; if ( optarg[1] ) { args->clevel = strtol(optarg+1,&tmp,10); if ( *tmp || args->clevel<0 || args->clevel>9 ) error("Could not parse argument: --compression-level %s\n", optarg+1); } break; case 'l': args->clevel = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --compression-level %s\n", optarg); args->output_type |= FT_GZ; break; case 'o': args->fn_out = optarg; break; case 'H': args->print_header = 0; break; case 'h': args->header_only = 1; break; case 4 : args->print_header = 1; args->header_only = 0; break; case 't': args->targets_list = optarg; break; case 'T': args->targets_list = optarg; targets_is_file = 1; break; case 'r': args->regions_list = optarg; break; case 'R': args->regions_list = optarg; regions_is_file = 1; break; case 's': args->sample_names = optarg; break; case 'S': args->sample_names = optarg; args->sample_is_file = 1; break; case 1 : args->force_samples = 1; break; case 'a': args->trim_alts = 1; args->calc_ac = 1; break; case 'A': args->trim_star_allele++; break; case 'I': args->update_info = 0; break; case 'G': args->sites_only = 1; break; case 'f': args->files->apply_filters = optarg; break; case 'k': args->known = 1; break; case 'n': args->novel = 1; break; case 'm': args->min_alleles = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --min-alleles %s\n", optarg); break; case 'M': args->max_alleles = strtol(optarg,&tmp,10); if ( *tmp ) error("Could not parse argument: --max-alleles %s\n", optarg); break; case 'v': args->include_types = optarg; break; case 'V': args->exclude_types = optarg; break; case 'e': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; case 'i': if ( args->filter_str ) error("Error: only one -i or -e expression can be given, and they cannot be combined\n"); args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; case 'c': { args->min_ac_type = ALLELE_NONREF; if ( sscanf(optarg,"%d:%8s",&args->min_ac, allele_type)!=2 && sscanf(optarg,"%d",&args->min_ac)!=1 ) error("Error: Could not parse --min-ac %s\n", optarg); set_allele_type(&args->min_ac_type, allele_type); args->calc_ac = 1; break; } case 'C': { args->max_ac_type = ALLELE_NONREF; if ( sscanf(optarg,"%d:%8s",&args->max_ac, allele_type)!=2 && sscanf(optarg,"%d",&args->max_ac)!=1 ) error("Error: Could not parse --max-ac %s\n", optarg); set_allele_type(&args->max_ac_type, allele_type); args->calc_ac = 1; break; } case 'q': { args->min_af_type = ALLELE_NONREF; if ( sscanf(optarg,"%f:%8s",&args->min_af, allele_type)!=2 && sscanf(optarg,"%f",&args->min_af)!=1 ) error("Error: Could not parse --min-af %s\n", optarg); set_allele_type(&args->min_af_type, allele_type); args->calc_ac = 1; break; } case 'Q': { args->max_af_type = ALLELE_NONREF; if ( sscanf(optarg,"%f:%8s",&args->max_af, allele_type)!=2 && sscanf(optarg,"%f",&args->max_af)!=1 ) error("Error: Could not parse --max-af %s\n", optarg); set_allele_type(&args->max_af_type, allele_type); args->calc_ac = 1; break; } case 'x': args->private_vars |= FLT_INCLUDE; args->calc_ac = 1; break; case 'X': args->private_vars |= FLT_EXCLUDE; args->calc_ac = 1; break; case 'u': args->uncalled |= FLT_INCLUDE; args->calc_ac = 1; break; case 'U': args->uncalled |= FLT_EXCLUDE; args->calc_ac = 1; break; case 'p': args->phased |= FLT_INCLUDE; break; // phased case 'P': args->phased |= FLT_EXCLUDE; break; // exclude-phased case 'g': { if ( !strcasecmp(optarg,"hom") ) args->gt_type = GT_NEED_HOM; else if ( !strcasecmp(optarg,"het") ) args->gt_type = GT_NEED_HET; else if ( !strcasecmp(optarg,"miss") ) args->gt_type = GT_NEED_MISSING; else if ( !strcasecmp(optarg,"^hom") ) args->gt_type = GT_NO_HOM; else if ( !strcasecmp(optarg,"^het") ) args->gt_type = GT_NO_HET; else if ( !strcasecmp(optarg,"^miss") ) args->gt_type = GT_NO_MISSING; else error("The argument to -g not recognised. Expected one of hom/het/miss/^hom/^het/^miss, got \"%s\".\n", optarg); break; } case 2 : args->targets_overlap = parse_overlap_option(optarg); if ( args->targets_overlap < 0 ) error("Could not parse: --targets-overlap %s\n",optarg); break; case 3 : args->regions_overlap = parse_overlap_option(optarg); if ( args->regions_overlap < 0 ) error("Could not parse: --regions-overlap %s\n",optarg); break; case 9 : args->n_threads = strtol(optarg, 0, 0); break; case 8 : args->record_cmd_line = 0; break; case 'W': if (!(args->write_index = write_index_parse(optarg))) error("Unsupported index format '%s'\n", optarg); break; case '?': usage(args); break; default: error("Unknown argument: %s\n", optarg); } } if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); if ( args->private_vars > FLT_EXCLUDE ) error("Only one of -x or -X can be given.\n"); if ( args->uncalled > FLT_EXCLUDE ) error("Only one of -u or -U can be given.\n"); if ( args->phased > FLT_EXCLUDE ) error("Only one of -p or -P can be given.\n"); if ( args->sample_names && args->update_info) args->calc_ac = 1; char *fname = NULL; if ( optind>=argc ) { if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin else usage(args); } else fname = argv[optind]; // read in the regions from the command line if ( args->regions_list ) { bcf_sr_set_opt(args->files,BCF_SR_REGIONS_OVERLAP,args->regions_overlap); if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) error("Failed to read the regions: %s\n", args->regions_list); } else if ( optind+1 < argc ) { int i; kstring_t tmp = {0,0,0}; kputs(argv[optind+1],&tmp); for (i=optind+2; ifiles, tmp.s, 0)<0 ) error("Failed to read the regions: %s\n", tmp.s); free(tmp.s); } if ( args->targets_list ) { bcf_sr_set_opt(args->files,BCF_SR_TARGETS_OVERLAP,args->targets_overlap); if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", args->targets_list); } if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to read from %s: %s\n", !strcmp("-",fname)?"standard input":fname,bcf_sr_strerror(args->files->errnum)); init_data(args); bcf_hdr_t *out_hdr = args->hnull ? args->hnull : (args->hsub ? args->hsub : args->hdr); if (args->print_header) { if ( bcf_hdr_write(args->out, out_hdr)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->fn_out); } else if ( args->output_type & FT_BCF ) error("BCF output requires header, cannot proceed with -H\n"); if ( init_index2(args->out,out_hdr,args->fn_out, &args->index_fn, args->write_index) < 0 ) error("Error: failed to initialise index for %s\n",args->fn_out); int ret = 0; if (!args->header_only) { while ( bcf_sr_next_line(args->files) ) { bcf1_t *line = args->files->readers[0].buffer[0]; if ( line->errcode && out_hdr!=args->hdr ) error("Undefined tags in the header, cannot proceed in the sample subset mode.\n"); if ( subset_vcf(args, line) && bcf_write1(args->out, out_hdr, line)!=0 ) error("[%s] Error: cannot write to %s\n", __func__,args->fn_out); } ret = args->files->errnum; if ( ret ) fprintf(stderr,"Error: %s\n", bcf_sr_strerror(args->files->errnum)); } if (args->write_index) { if (bcf_idx_save(args->out) < 0) { if ( hts_close(args->out)!=0 ) error("Error: close failed %s\n", args->fn_out?args->fn_out:"stdout"); error("Error: cannot write to index %s\n", args->index_fn); } free(args->index_fn); } if ( hts_close(args->out)!=0 ) error("Error: close failed %s\n", args->fn_out?args->fn_out:"stdout"); destroy_data(args); bcf_sr_destroy(args->files); free(args); return ret; } bcftools-1.21/vcmp.c000066400000000000000000000106711467060157400144000ustar00rootroot00000000000000/* vcmp.c -- reference allele utility functions. Copyright (C) 2013-2015, 2018 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "vcmp.h" struct _vcmp_t { char *dref; int ndref, mdref; // ndref: positive when ref1 longer, negative when ref2 is longer int nmatch; int *map, mmap, nmap; int *map_dip, mmap_dip, nmap_dip; }; vcmp_t *vcmp_init() { return (vcmp_t*)calloc(1,sizeof(vcmp_t)); } void vcmp_destroy(vcmp_t *vcmp) { free(vcmp->map_dip); free(vcmp->map); free(vcmp->dref); free(vcmp); } int vcmp_set_ref(vcmp_t *vcmp, char *ref1, char *ref2) { vcmp->ndref = 0; char *a = ref1, *b = ref2; while ( *a && *b && toupper(*a)==toupper(*b) ) { a++; b++; } if ( !*a && !*b ) return 0; if ( *a && *b ) return -1; // refs not compatible int i; if ( *a ) // ref1 is longer { vcmp->nmatch = b-ref2; while ( *a ) a++; vcmp->ndref = (a-ref1) - vcmp->nmatch; hts_expand(char,vcmp->ndref+1,vcmp->mdref,vcmp->dref); for (i=0; indref; i++) vcmp->dref[i] = toupper(ref1[vcmp->nmatch+i]); vcmp->dref[vcmp->ndref] = 0; return 0; } // ref2 is longer vcmp->nmatch = a-ref1; while ( *b ) b++; vcmp->ndref = (b-ref2) - vcmp->nmatch; hts_expand(char,vcmp->ndref+1,vcmp->mdref,vcmp->dref); for (i=0; indref; i++) vcmp->dref[i] = toupper(ref2[vcmp->nmatch+i]); vcmp->dref[vcmp->ndref] = 0; vcmp->ndref *= -1; return 0; } int vcmp_find_allele(vcmp_t *vcmp, char **als1, int nals1, char *al2) { int i, j; for (i=0; indref ) { if ( !*a && !*b ) break; // found continue; } // the prefixes match if ( *a ) { if ( vcmp->ndref<0 ) continue; for (j=0; jndref; j++) if ( !a[j] || toupper(a[j])!=vcmp->dref[j] ) break; if ( j!=vcmp->ndref || a[j] ) continue; break; // found } if ( vcmp->ndref>0 ) continue; for (j=0; j<-vcmp->ndref; j++) if ( !b[j] || toupper(b[j])!=vcmp->dref[j] ) break; if ( j!=-vcmp->ndref || b[j] ) continue; break; // found } if (i==nals1) return -1; return i; } int *vcmp_map_ARvalues(vcmp_t *vcmp, int n, int nals1, char **als1, int nals2, char **als2) { if ( vcmp_set_ref(vcmp,als1[0],als2[0]) < 0 ) return NULL; vcmp->nmap = n; hts_expand(int, vcmp->nmap, vcmp->mmap, vcmp->map); int i, ifrom = n==nals2 ? 0 : 1; for (i=ifrom; imap[i-ifrom] = vcmp_find_allele(vcmp, als1+ifrom, nals1-ifrom, als2[i]); } return vcmp->map; } int *vcmp_map_dipGvalues(vcmp_t *vcmp, int *nmap) { vcmp->nmap_dip = vcmp->nmap*(vcmp->nmap+1)/2; hts_expand(int, vcmp->nmap_dip, vcmp->mmap_dip, vcmp->map_dip); int i, j, k = 0; for (i=0; inmap; i++) { for (j=0; j<=i; j++) { vcmp->map_dip[k] = vcmp->map[i]>=0 && vcmp->map[j]>=0 ? bcf_alleles2gt(vcmp->map[i],vcmp->map[j]) : -1; k++; } } *nmap = k; return vcmp->map_dip; } bcftools-1.21/vcmp.h000066400000000000000000000046061467060157400144060ustar00rootroot00000000000000/* vcmp.h -- reference allele utility functions. Copyright (C) 2013-2015 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #ifndef __VCMP_H__ #define __VCMP_H__ typedef struct _vcmp_t vcmp_t; vcmp_t *vcmp_init(void); void vcmp_destroy(vcmp_t *vcmp); /* * vcmp_set_ref() - sets and compares reference alleles * Returns 0 on success or -1 if alleles not compatible */ int vcmp_set_ref(vcmp_t *vcmp, char *ref1, char *ref2); /* * vcmp_find_allele() * @param als1: alternate alleles to ref1 above * @param al2: alternate allele to ref2 above * Returns -1 if not found or 0-based index to als1 of matching allele */ int vcmp_find_allele(vcmp_t *vcmp, char **als1, int nals1, char *al2); /* * vcmp_map_ARvalues() - Create mapping for Number=A,R tag values * @param number: nals2 for Number=R, nals2-1 for Number=A * @param nals1: number of alleles * @param als1: alleles * * Returns pointer to an array of size nals2 with mapping from als2 * to als1 or NULL if REFs (als1[0] and als2[0]) are not compatible. * If i is the index of an allele in als2, ret[i] is the index of matching * allele in als1 or -1 if als2 does not have a matching allele. * The caller must not free the array. */ int *vcmp_map_ARvalues(vcmp_t *vcmp, int number, int nals1, char **als1, int nals2, char **als2); int *vcmp_map_dipGvalues(vcmp_t *vcmp, int *nmap); #endif bcftools-1.21/version.c000066400000000000000000000136751467060157400151270ustar00rootroot00000000000000/* version.c -- report version numbers for plugins. Copyright (C) 2014-2024 Genome Research Ltd. Author: Petr Danecek Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. */ #include #include #include #include #include #include #include "bcftools.h" #include "version.h" void version(const char **bcftools_version, const char **htslib_version) { *bcftools_version = BCFTOOLS_VERSION; *htslib_version = hts_version(); } void error(const char *format, ...) { va_list ap; va_start(ap, format); vfprintf(stderr, format, ap); va_end(ap); exit(-1); } void error_errno(const char *format, ...) { va_list ap; int e = errno; va_start(ap, format); vfprintf(stderr, format, ap); va_end(ap); if (e) { fprintf(stderr, ": %s\n", strerror(e)); } else { fprintf(stderr, "\n"); } exit(-1); } const char *hts_bcf_wmode(int file_type) { if ( file_type == FT_BCF ) return "wbu"; // uncompressed BCF if ( file_type & FT_BCF ) return "wb"; // compressed BCF if ( file_type & FT_GZ ) return "wz"; // compressed VCF return "w"; // uncompressed VCF } const char *hts_bcf_wmode2(int file_type, const char *fname) { if ( !fname ) return hts_bcf_wmode(file_type); const char *end = fname ? strstr(fname, HTS_IDX_DELIM) : NULL; if ( !end ) end = fname ? fname + strlen(fname) : fname; int len = end - fname; if ( len >= 4 && !strncasecmp(".bcf",fname+len-4,4) ) return hts_bcf_wmode(FT_BCF|FT_GZ); if ( len >= 4 && !strncasecmp(".vcf",fname+len-4,4) ) return hts_bcf_wmode(FT_VCF); if ( len >= 7 && !strncasecmp(".vcf.gz",fname+len-7,7) ) return hts_bcf_wmode(FT_VCF|FT_GZ); if ( len >= 8 && !strncasecmp(".vcf.bgz",fname+len-8,8) ) return hts_bcf_wmode(FT_VCF|FT_GZ); return hts_bcf_wmode(file_type); } void set_wmode(char dst[8], int file_type, const char *fname, int clevel) { const char *ret = NULL; const char *end = fname ? strstr(fname, HTS_IDX_DELIM) : NULL; if ( !end ) end = fname ? fname + strlen(fname) : fname; int len = end - fname; if ( len >= 4 && !strncasecmp(".bcf",fname+len-4,4) ) ret = hts_bcf_wmode(file_type & FT_BCF ? file_type : FT_BCF|FT_GZ); else if ( len >= 4 && !strncasecmp(".vcf",fname+len-4,4) ) ret = hts_bcf_wmode(FT_VCF); else if ( len >= 7 && !strncasecmp(".vcf.gz",fname+len-7,7) ) ret = hts_bcf_wmode(FT_VCF|FT_GZ); else if ( len >= 8 && !strncasecmp(".vcf.bgz",fname+len-8,8) ) ret = hts_bcf_wmode(FT_VCF|FT_GZ); else ret = hts_bcf_wmode(file_type); if ( clevel>=0 && clevel<=9 ) { if ( strchr(ret,'v') || strchr(ret,'u') ) error("Error: compression level (%d) cannot be set on uncompressed streams (%s)\n",clevel,fname); len = strlen(ret); if ( len>6 ) error("Fixme: %s\n", ret); sprintf(dst, "%s%d", ret, clevel); } else strcpy(dst, ret); } int parse_overlap_option(const char *arg) { if ( strcasecmp(arg, "pos") == 0 || strcmp(arg, "0") == 0 ) return 0; else if ( strcasecmp(arg, "record") == 0 || strcmp(arg, "1") == 0 ) return 1; else if ( strcasecmp(arg, "variant") == 0 || strcmp(arg, "2") == 0 ) return 2; else return -1; } // Used to set args->write_index in CLI. // It will be true if set correctly. // Note due to HTS_FMT_CSI being zero we have to use an additional bit. int write_index_parse(char *arg) { int fmt = HTS_FMT_CSI; if (arg) { if (strcmp(arg, "csi") == 0 || strcmp(arg, "=csi") == 0) fmt = HTS_FMT_CSI; else if (strcmp(arg, "tbi") == 0 || strcmp(arg, "=tbi") == 0) fmt = HTS_FMT_TBI; else return 0; } return 128 | fmt; } // See also samtools/sam_utils.c auto_index() int init_index2(htsFile *fh, bcf_hdr_t *hdr, const char *fname, char **idx_fname, int idx_fmt) { // Nothing to do == success. This simplifies the main code simpler. if (!idx_fmt) return 0; int min_shift; char *idx_suffix; if (idx_fmt && (idx_fmt&127) == HTS_FMT_TBI && fh->format.format == vcf) { min_shift = 0; // TBI idx_suffix = "tbi"; } else { min_shift = 14; // CSI idx_suffix = "csi"; } if ( !fname || !*fname || !strcmp(fname, "-") ) return -1; char *delim = strstr(fname, HTS_IDX_DELIM); if (delim) { delim += strlen(HTS_IDX_DELIM); *idx_fname = strdup(delim); if ( !*idx_fname ) return -1; size_t l = strlen(*idx_fname); if ( l >= 4 && strcmp(*idx_fname + l - 4, ".tbi")==0 ) min_shift = 0; } else { if ( !(*idx_fname = malloc(strlen(fname)+6)) ) return -1; sprintf(*idx_fname, "%s.%s", fname, idx_suffix); } if ( bcf_idx_init(fh, hdr, min_shift, *idx_fname) < 0 ) return -1; return 0; } int init_index(htsFile *fh, bcf_hdr_t *hdr, const char *fname, char **idx_fname) { return init_index2(fh,hdr, fname, idx_fname, HTS_FMT_CSI); } bcftools-1.21/version.sh000077500000000000000000000027221467060157400153110ustar00rootroot00000000000000#!/bin/sh # version.sh # # Author : Petr Danecek # # Copyright (C) 2018-2021 Genome Research Ltd. # # Permission is hereby granted, free of charge, to any person obtaining a copy # of this software and associated documentation files (the "Software"), to deal # in the Software without restriction, including without limitation the rights # to use, copy, modify, merge, publish, distribute, sublicense, and/or sell # copies of the Software, and to permit persons to whom the Software is # furnished to do so, subject to the following conditions: # # The above copyright notice and this permission notice shall be included in # all copies or substantial portions of the Software. # # THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR # IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, # FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL # THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER # LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING # FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER # DEALINGS IN THE SOFTWARE. # Master version, for use in tarballs or non-git source copies VERSION=1.21 # If we have a git clone, then check against the current tag if [ -e .git ] then # If we ever get to 10.x this will need to be more liberal VERSION=`git describe --match '[0-9].[0-9]*' --dirty --always` fi echo $VERSION